LOCUS       DAMJWO010000001       126750 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.001, whole genome shotgun sequence.
ACCESSION   DAMJWO010000001 DAMJWO010000000
VERSION     DAMJWO010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 126750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 126750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..126750
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.001"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(15..1364)
                     /locus_tag="PC366_000001"
     CDS             complement(15..1364)
                     /locus_tag="PC366_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2575565.1"
                     /translation="MEKAKKLGLFSMILLGINSIIGSGIFLLPGKVYSLAGQNSMFIY
                     IFATLLVLSILLCFAEVGSMFDKNGGAYLYSKKAFGDFIGFEVGTMSWFIRIISWSTL
                     AVGFATALGSFWPESATEYKGCIAAILVTLLSINSLFGIKSTKIMNNVITIAKLVPLI
                     VFVIVGIFFIKFVNIVPSGNVVNSSMGPAIILVFYAFTGFESFIVASGEMENPKKNLP
                     IALITTIFICAIIYILIQIVCMGILGDRLFENSIPIADASSVFLGNYGKVFISVATLI
                     SIFGINIGSSIVTPKCGSSLAEEGSLPAFIGKTNKYGAPYVAIIISLICCIPLVLTGS
                     FEQLAVMSVIARFAQYIPTCLSVIVLRKRTDVKASFKIPFGPVIPMVAILGSLWLLQQ
                     AWAEDISKPITQNRVLIGLGAMLLIAPLYIFMKKNKEIEHKNKSEDSKLYISREKIQ"
     gene            complement(1401..2621)
                     /locus_tag="PC366_000002"
     CDS             complement(1401..2621)
                     /locus_tag="PC366_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2575566.1"
                     /translation="MQQALKLKYQTKELGKDFVIESCNSIKPWLINIRRELHKIPELA
                     LEENLTKQKVISYLKEIGIDYMEFTKHNGIMAYILKESADKTICIRADMDALPIEEEN
                     NIPYKSIHSGKMHACGHDAHTTMLLGACKVLHSIKDKLNVNVKFLFQPAEEGFGGAKF
                     LVEDGCLENPKADYIFGLHVMPHIETGLIETKYDTLNASVDTIKISIKGKRAHGAYPE
                     NGIDAIVTASQIVTSLQTIISRNLEPNNAAVLTIGKIYGGDAHNVICEDVKLEGTLRT
                     LNSKTRNFMIDKIAKIVGDTASAFGCVGTLHVSDENYPAVINEKELVDTVISSTKELL
                     GEEKFILRPNPSLGGEDFSFYTEHCKGAFFHLGCKNEEKGLISPLHTSSFNIDEDCLP
                     IGVMMHVMNTLYFN"
     gene            complement(2990..5002)
                     /locus_tag="PC366_000003"
     CDS             complement(2990..5002)
                     /locus_tag="PC366_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2575567.1"
                     /translation="MKKSVALVNDSRKDLIDFLENNLKLVFGDSININRYFINEINDN
                     DIINDDVILVMSVERLDKIINNILDKKKVIVVRRTFREDKIYNLLSLPQGTNALIVND
                     SDETTLETISLFYKIGVTNIRPIPYMNDNNYKNIKIAITPGVPEKVPSFISDIFDLGH
                     RYIDISTFIEIINLLQIDSKEIQSNLVKYSEEIISLDTGIKDKYKELFLKIEELDTIL
                     NLSKDGILFTSKDGEINTYNSKVKDILDINEDIYGKYIDDIFVDSLKVLLSEKEILDK
                     VVVFNKKYINVNKKNIYNRDEKMGTYYSLQEITYIKKLEQNLTKKLREKGQIAKYTFK
                     DIKTNSPKMFECIDLAKKVSKSDLSILIRGESGTGKELIAQSIHNNSNRKNQPFIAVN
                     CAAVPENLLESQLFGYDKGTFTGGLKDGKQGLFELANNGTIFLDEIGDMPLELQTKLL
                     RVLQEKQIMPVGSHNVINIDVRIISATNKNLEQMIDNSQFREDLYYRLNTIPINIPPL
                     RERKEDILIIMEDLINKKLVITPEAKKLIQNYMWKGNIRELQNVTSYLNIMCEDIVLE
                     KDLPPNLRSSDNKNTSLKLKYSKNDILNILEILILNKESDVGIGRGLILKALLDKNLQ
                     ITEGKIKKIFEYLKKEELIICSSGRYGSKITQKGEDFYNKLKYKGL"
     gene            5473..6123
                     /locus_tag="PC366_000004"
     CDS             5473..6123
                     /locus_tag="PC366_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HDF2575568.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCISNKQENNVCNIKAI
                     RNFSEIYSISRKSRYHSLLKLTEKEIVKKMGNTYEILNYDELHKLAFEVKEFLEDE"
     gene            complement(6263..7639)
                     /locus_tag="PC366_000005"
     CDS             complement(6263..7639)
                     /locus_tag="PC366_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2575569.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVSNIRKVTGLTCVLA
                     IVLSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAVSTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYLYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAIGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(7655..9568)
                     /locus_tag="PC366_000006"
     CDS             complement(7655..9568)
                     /locus_tag="PC366_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2575570.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIEMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELQPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLEIEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            9704..10336
                     /locus_tag="PC366_000007"
     CDS             9704..10336
                     /locus_tag="PC366_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HDF2575571.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            10475..11014
                     /locus_tag="PC366_000008"
     CDS             10475..11014
                     /locus_tag="PC366_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HDF2575572.1"
                     /translation="MVFVEELWKKAIEFHGHECPGLAIGFKAALAARKYLGCKQSGDE
                     EIVCISENDACGIDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FQMDREGYKKYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFNKYERFYEEY"
     gene            complement(11190..11360)
                     /locus_tag="PC366_000009"
     CDS             complement(11190..11360)
                     /locus_tag="PC366_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004619190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2575573.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDAGSCIDCGSC
                     AGACPVDAPQPE"
     gene            11645..12712
                     /locus_tag="PC366_000010"
     CDS             11645..12712
                     /locus_tag="PC366_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HDF2575574.1"
                     /translation="MKNKLVYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFEKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSIEAVSIANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVMGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPNIIPTSITSSSSRNNYQPKVL
                     DGSEKDRVLNKLEKISKDLNK"
     gene            12882..14783
                     /gene="cooS"
                     /locus_tag="PC366_000011"
     CDS             12882..14783
                     /gene="cooS"
                     /locus_tag="PC366_000011"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HDF2575575.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVVKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFKLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAEYIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
     gene            14776..15249
                     /locus_tag="PC366_000012"
     CDS             14776..15249
                     /locus_tag="PC366_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2575576.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSKHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRG"
     gene            15224..16450
                     /locus_tag="PC366_000013"
     CDS             15224..16450
                     /locus_tag="PC366_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2575577.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENVYSRCMLH
                     HVISEHRTLKQINFVDEDFMEQNNVKWIAGKTVKGIDINKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLRDGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIVLDNSKNVT
                     GVAFSNGEVLDADMVIVATGVKPNADFLDGTGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMVGKDKKIEDEFAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGINDYKKFVFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDVCY
                     ADFFNIKENGEFCYSV"
     gene            complement(16589..17776)
                     /locus_tag="PC366_000014"
     CDS             complement(16589..17776)
                     /locus_tag="PC366_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2575578.1"
                     /translation="MNITKNFLKDYLEKFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNARIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRVVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKSFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
     gene            18049..18873
                     /locus_tag="PC366_000015"
     CDS             18049..18873
                     /locus_tag="PC366_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDF2575579.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIIDDGILIYKNKVLA
                     GISAKQANTTIEAVKRAIFYNLEHRQEVREAIKKENIRKILIIGTSKKMVNQIVERLS
                     IGRVCKFINIQDISTKYEIEIAKQARKEGNHVIPVPAVEIKSMASGLSINSLKRLFRK
                     GNNRNMVVLEKTIIRPTFSYIGKFYISADVIKQIIEYEVYNFGSIDRINKINIENCNN
                     FMNIFVSININDLETIKKIEDIQQTIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            19002..20267
                     /gene="gluD"
                     /locus_tag="PC366_000016"
     CDS             19002..20267
                     /gene="gluD"
                     /locus_tag="PC366_000016"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HDF2575580.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            20460..21116
                     /locus_tag="PC366_000017"
     CDS             20460..21116
                     /locus_tag="PC366_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HDF2575581.1"
                     /translation="MYFLPPHDYKLEELDWIFGHELMYFKSKDLHLKYLVLFLKIVYW
                     FNPFIYIMEKYMDLDCELYCDERVLKNCTVQQKQEYALTIVNSMKRGINFSNKFVTGL
                     NKQSDIRKRVMNMFSEKHKNGILMALIISLFSSITFFKFDSTSLIEENDFLERSRYAF
                     EGRQEDMFVTIDSTYADAPIKLRKEHEENCRVNGIVPKDSDSIEIIPRFYKDCMDLKK
                     "
     gene            21447..22580
                     /locus_tag="PC366_000018"
     CDS             21447..22580
                     /locus_tag="PC366_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HDF2575582.1"
                     /translation="MSNFILNGIFRTVIVSSLSILLILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKHININNINLEGFNNVSTISNNIILYTWIITVVVY
                     LIYTIFKYIKLKNLINDLSYDVDDREIVNLYKNILEEFNITKDIKLKYSYEVETPAFF
                     NSCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHI
                     DLDCELYCDERVLKNRNSEEKKDYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMN
                     MFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLNVLPKGFEDLRTVSSIRFSVIGF
                     TYADAPKNMREEYKINCESLGLIPKDSDKIEVGVEYYDSLLND"
     gene            23507..24529
                     /locus_tag="PC366_000019"
     CDS             23507..24529
                     /locus_tag="PC366_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2575583.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEDNGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQVNPSIDQNVDSTNNNQQNNANTNQQNNNSNVPTANSNA
                     VQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTV
                     SKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVSVTSINSSYYTARFV
                     TAKRIL"
     gene            24825..25745
                     /gene="pyrB"
                     /locus_tag="PC366_000020"
     CDS             24825..25745
                     /gene="pyrB"
                     /locus_tag="PC366_000020"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HDF2575584.1"
                     /translation="MLKSRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMRIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLESHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDS
                     DDRAVYFKQAKYGMYVRMALIIKLLGINED"
     gene            25784..26476
                     /locus_tag="PC366_000021"
     CDS             25784..26476
                     /locus_tag="PC366_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HDF2575585.1"
                     /translation="MYKILENIYIGEDMYRMKVKGNFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDNIKLEGPYGNGYAKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEDEYKQVCNKVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNGGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            26469..27371
                     /locus_tag="PC366_000022"
     CDS             26469..27371
                     /locus_tag="PC366_000022"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HDF2575586.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETPSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            27456..28040
                     /locus_tag="PC366_000023"
     CDS             27456..28040
                     /locus_tag="PC366_000023"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HDF2575587.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            28255..29181
                     /locus_tag="PC366_000024"
     CDS             28255..29181
                     /locus_tag="PC366_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketopantoate reductase family protein"
                     /protein_id="HDF2575588.1"
                     /translation="MKNQLNENHKKVVFFGVGAVGATFAEQFFNSKYDFKILCDNERK
                     KRYLEEGFIINGKRYDFNYVTKDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIGKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYILSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKDISLTEDDVENSLHRILEHSKEGRTSMLQDVEAHRPTEVDMF
                     SKNICKLGKKYSIPTPINQTLFYMIKVIESRF"
     gene            complement(29233..30123)
                     /locus_tag="PC366_000025"
     CDS             complement(29233..30123)
                     /locus_tag="PC366_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2575589.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSQKYPDIYVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYNSHLLKDFSFDKLQDQKWIVREDGSGTRDYLDMFLSVKEIIPKSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            30311..31342
                     /locus_tag="PC366_000026"
     CDS             30311..31342
                     /locus_tag="PC366_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HDF2575590.1"
                     /translation="MLKKKSSLTLKTIREILPGLFISVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGAIVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKIVRVIFLVVVVLVFGHMKNQSNREILEEEKDEIKKKKVTIPWYVIGFFITCALF
                     SMNIIPKEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFVGTVQVVS
                     AVVLIKIFI"
     gene            31636..32511
                     /locus_tag="PC366_000027"
     CDS             31636..32511
                     /locus_tag="PC366_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxoguanine DNA glycosylase"
                     /protein_id="HDF2575591.1"
                     /translation="MNVYEKGNGVILEGVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     RGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYTEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGNEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDEVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            32529..34019
                     /gene="cls"
                     /locus_tag="PC366_000028"
     CDS             32529..34019
                     /gene="cls"
                     /locus_tag="PC366_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDF2575592.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGVGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNVGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTDDFFEDLSHCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            34212..34496
                     /locus_tag="PC366_000029"
     CDS             34212..34496
                     /locus_tag="PC366_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HDF2575593.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            34529..36157
                     /gene="groL"
                     /locus_tag="PC366_000030"
     CDS             34529..36157
                     /gene="groL"
                     /locus_tag="PC366_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HDF2575594.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVIVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTEAAVADLPEKEDAGMPGMGGGMPGMM"
     gene            36419..37159
                     /gene="larB"
                     /locus_tag="PC366_000031"
     CDS             36419..37159
                     /gene="larB"
                     /locus_tag="PC366_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HDF2575595.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYNHAEYEEASK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLASMINKL"
     gene            37243..37977
                     /gene="larC"
                     /locus_tag="PC366_000032"
     CDS             37243..37977
                     /gene="larC"
                     /locus_tag="PC366_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HDF2575596.1"
                     /translation="MSEKILYFDIISGISGDMTLASLLNLGVPKEIFLEEIHKLRMSD
                     EFNINISSKTENGIVGTKVEVITKEKHTHRNLVDIFEVIDKSTLNENVKSKAKKIFMV
                     IGEAEAKVHGTTIDKIHFHEVGAIDSIVDIVGASILVDLLCVDKVCASTVSVGSGFVK
                     CEHGIIPIPAPATIEILKGVPIKLNNVNGECTTPTGAAIIKVLCDEFVDELEFSPKQI
                     GYGIGHKKFEVPNILRTVLGEKKKKN"
     gene            38007..38426
                     /locus_tag="PC366_000033"
     CDS             38007..38426
                     /locus_tag="PC366_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF111 family protein"
                     /protein_id="HDF2575597.1"
                     /translation="MSSEIYSYLYEKILDEKALDIYTESIYMKKNRPATKVSILCNES
                     DLEKFIKILLLETSTFGVRYNAYNREILERKFVKLDTKYGVVTVKLGYYKGKLVKVTP
                     EYNECKTIAKNEDIPIKKVFADINFRIKEEFSENLLT"
     regulatory      38486..38587
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            38808..40343
                     /gene="guaA"
                     /locus_tag="PC366_000034"
     CDS             38808..40343
                     /gene="guaA"
                     /locus_tag="PC366_000034"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDF2575598.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTSITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            40882..42312
                     /locus_tag="PC366_000035"
     CDS             40882..42312
                     /locus_tag="PC366_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2575599.1"
                     /translation="MILNQIFIEDGGIMRNKIIIGITFSLVLLMSGCASKQTAEINVL
                     ATTDLHGVIPYELTSYVKEERKKDKNLTLVDAGDFFDSGEVFGSSMDSYFSARYKDGD
                     NNTESYIETPISKDMKEVGYDVAVLGNHEFISNNKFYLDNMISDFEKQKINILSANTY
                     KKNGDSYTKPYIIKNINTPEGNVKLGILGLTIKEVGERKQWKDGKLVDSKSLELKDQE
                     GYNGELYMNDLVEDAKKWVGIMEKEKPDIIVAVAHTGEKPKKPRNPGNRIQDLAQQVD
                     GIDAIVAGHNHVQIEQHDYKNKSGENVIVTEPGKHGEYISKINFKLEKNNDKWNIVDK
                     SSKLIKFEKNQESDKFGEFISSINKVSKDKKEIRLSEVKTPEWDKIYVFKSGTSADDI
                     YKTIGYKWRNISSPKGDDMVQIVVMNNNKPVSYIYGEAEVMPINIKCDESEYKNNVVT
                     IYPNKNDKFKIEKGKQEYSINLKHIQ"
     gene            complement(42460..43335)
                     /locus_tag="PC366_000036"
     CDS             complement(42460..43335)
                     /locus_tag="PC366_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2575600.1"
                     /translation="MINIRYLEILEAIEQTGTFTGAAKKLHITQSAVSHAIAELEQQA
                     ETSLFDRLPRGVCLTRCGISLLDEARSILTACRNLDKKISRLEECTPINIVSSITIAS
                     FLLPPILSRLKNSFPSLKVNVRVESANSAMDILKSGEADICFWEGIEPQGAFRTILLG
                     SYKLCVACAPTFPLSEQTLSLRQLCTFPLLLREQGSAIRDTLDSVLSLSNQKAYPVWE
                     SVNSFALIKAAEAGLGITILPENLLLDSLLHKKLRLIELDEIDMENKMLAILHKDKNI
                     TQPLEIILDNISNVL"
     gene            43455..44018
                     /locus_tag="PC366_000037"
     CDS             43455..44018
                     /locus_tag="PC366_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF2575601.1"
                     /translation="MNQSRKIYFWLLIINLFISTFTFGGGYVVVPMIRRYFVNQKQFF
                     TEDDLMSMAAVAQSTPGAIAINLSALAGYRVAGTLGVVISCTAAIIPPLVILGLVSAF
                     YTTFISNAIVTAVLKGMQAGVAALIVDLIIDMCSMILKQRSLFLSTMIPIAFFANFVM
                     SINVIFILSVCCFVCVMQVFYKKRENK"
     gene            44015..44581
                     /locus_tag="PC366_000038"
     CDS             44015..44581
                     /locus_tag="PC366_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF2575602.1"
                     /translation="MNTIWNLFFIFLKIGLFSIGGGYAIIPLIQEKVVNQTGWISEKM
                     FTDIITISQMTPGPLAVNTSTFVGLQIGGFWGAVAATLGCVLCGVVISLFLYNFFQKH
                     QNSTYIFEILNGLKSASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFV
                     ILLIVRKWKINPIVIIIISGILGIFFYL"
     gene            complement(44710..44946)
                     /locus_tag="PC366_000039"
     CDS             complement(44710..44946)
                     /locus_tag="PC366_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575603.1"
                     /translation="MLECFIAEDSKIKDGVNIPTLVFKTLHDRYFKTQYFDSYYNSLK
                     CKKKLVEINNVHNSYYIDSEKFCQEAYDWFVENQ"
     gene            complement(45256..48684)
                     /gene="uvrA"
                     /locus_tag="PC366_000040"
     CDS             complement(45256..48684)
                     /gene="uvrA"
                     /locus_tag="PC366_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2575604.1"
                     /translation="MKINNYKNQSIITNPKKFENKYQDLPKTPIELLKVVQSLVIHGD
                     QGKLYGISFNKQQSDEELLRTIPQMLKRIFEINSNPLTIPRNPKQRLVGMCRDYSLLL
                     VSLLRYRGFEARMRAGFANYFENELTYEDHWLVEYYDTLTKRWIRIDAQIDDIQKNYF
                     QINFDTHDVGKTDGFLTGSEAWIRCRQGHAHPDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSSGNIKIEDLNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELGNPLELEKKFKFAKAINKSIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNQITVITGVSGSGKSSLAFDTIYEEGKRRYFENLGNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGSQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKTPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLRGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIDAILYGTDDKI
                     YEFSFESKGRESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELPNQLQKNELSLVNDILTELKIRVSYLLK
                     VGLSYISTDRTAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEELRDKGNTVIVVEHDKDTILSADYIIDVGPNAGTKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKISSQNKIIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSIPNKNYTALTGFDAIDDFILMDQTPIGKSSRSTPATYINIF
                     DEIRSLFTETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYMADQWVTCNEC
                     QGKRYQKEILSIQYKGKTIADILDMEVAEAKTFFSDCSDIYRKLSLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGINGGEIVASGTPDEIKINPNSITGHFI"
     gene            49003..51237
                     /locus_tag="PC366_000041"
     CDS             49003..51237
                     /locus_tag="PC366_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2575605.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGI
                     IDLEGKAEFLSGKKFDLKNTASYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
                     LIGVSNKESMDEILNIDSFNGEGTIEIINSQGKTLFIGKNNELIKDLSYKYKDSADEP
                     WAQKMLNDFKNDKSGNITITSSKGVQCLLTYHPITRGLNDWHFLLIVPEDVVLGELNK
                     LNSFTIIMTFITTCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSMLVKP
                     LISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNILYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLIT
                     IQDHANTARKSFNKTHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSNFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAID
                     IIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFENFAYENNKIK
                     NIHY"
     gene            51493..53523
                     /locus_tag="PC366_000042"
     CDS             51493..53523
                     /locus_tag="PC366_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2575606.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKSFKISGEEDLIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESASLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENEIILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKEWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     IICQELGYSDERILFRQLNLSDLIGIDTIRIIDEDMKWEDAVKISSNILANCDFVSAQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIF
                     CLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV"
     gene            53520..53972
                     /locus_tag="PC366_000043"
     CDS             53520..53972
                     /locus_tag="PC366_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2575607.1"
                     /translation="MNKLVNVKCSFKIHANSKEEAIVSLVDVVSKEGYLIDKNQFLED
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDIPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED"
     gene            53974..55029
                     /locus_tag="PC366_000044"
     CDS             53974..55029
                     /locus_tag="PC366_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HDF2575608.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLIGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSI
                     IGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDE
                     EIEEDLDESIELIFEEL"
     gene            55096..55404
                     /locus_tag="PC366_000045"
     CDS             55096..55404
                     /locus_tag="PC366_000045"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HDF2575609.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
                     "
     gene            55508..56773
                     /locus_tag="PC366_000046"
     CDS             55508..56773
                     /locus_tag="PC366_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase,
                     non-catalytic subunit"
                     /protein_id="HDF2575610.1"
                     /translation="MKKLPIKTVVQRLLDLQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKIADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLSVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPDIGYEVGTEETNGGLTSTETYETFITRLKVELDNRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SQIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVDKTSNIRHVLLVNAIECGRWRK
                     WVVGEQKNLTTEEIFKNEVLSNEILDIAGHYTFNNDDVKKEIEVLYDNLSKNNIDGQR
                     FVVDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            56861..57577
                     /locus_tag="PC366_000047"
     CDS             56861..57577
                     /locus_tag="PC366_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF2575611.1"
                     /translation="MINLIFDVDDTLYNQLTPFYTAYNKVFSSIKDISIEDLYMSSRK
                     YSDEVFHMTENGEMPIKEMHIYRIMKAFEELGNSITEKDAQSFQDEYIYQQSQITLIP
                     EVERILNFSKERNINLGIITNGPSNHQRMKLKQLNIENWVDKSNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYVGDSYRNDVLGAKKAGWKSIWLNHRGHEVEELFYKPDFV
                     ILEHKDLISLFIKICSYKNM"
     gene            complement(57772..58065)
                     /locus_tag="PC366_000048"
     CDS             complement(57772..58065)
                     /locus_tag="PC366_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HDF2575612.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWVKPYDKPIQQLTCSYKESQNVID"
     gene            complement(58071..58286)
                     /locus_tag="PC366_000049"
     CDS             complement(58071..58286)
                     /locus_tag="PC366_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575613.1"
                     /translation="MRTLSETEKISLAAVIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAIQQFIVENEILISEEV"
     gene            complement(58831..59343)
                     /locus_tag="PC366_000050"
     CDS             complement(58831..59343)
                     /locus_tag="PC366_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2575614.1"
                     /translation="MLEVIKNRRSIRTYIDKNIEEDKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKELSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWAGVFPKNKVVNKVKQILDLPVKLVPYALISIGYSEEKNEFIDRFDEN
                     KIHRNVYKNR"
     gene            59793..60269
                     /gene="purE"
                     /locus_tag="PC366_000051"
     CDS             59793..60269
                     /gene="purE"
                     /locus_tag="PC366_000051"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HDF2575615.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     SIFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDKNLRG"
     gene            60275..60973
                     /locus_tag="PC366_000052"
     CDS             60275..60973
                     /locus_tag="PC366_000052"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDF2575616.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            60985..62352
                     /gene="purF"
                     /locus_tag="PC366_000053"
     CDS             60985..62352
                     /gene="purF"
                     /locus_tag="PC366_000053"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HDF2575617.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKENELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            62346..63422
                     /locus_tag="PC366_000054"
     CDS             62346..63422
                     /locus_tag="PC366_000054"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HDF2575618.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMEQYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHDIKAIAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVDERELHKSFNMGIGLVLIVDKENADDVVNFINNRENDNAAYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            63416..64009
                     /locus_tag="PC366_000055"
     CDS             63416..64009
                     /locus_tag="PC366_000055"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HDF2575619.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQGAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKLKLQGRRVFINE"
     gene            64002..65534
                     /gene="purH"
                     /locus_tag="PC366_000056"
     CDS             64002..65534
                     /gene="purH"
                     /locus_tag="PC366_000056"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HDF2575620.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEVLKQKKNLRILKLAKIEDSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKAKP
                     TDAQLKDMEFGMRVVKNMKSNAIAIVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            65545..66795
                     /gene="purD"
                     /locus_tag="PC366_000057"
     CDS             65545..66795
                     /gene="purD"
                     /locus_tag="PC366_000057"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HDF2575621.1"
                     /translation="MKILVVGGGGREHAICWKLSKEKNVEKVYCAPGNAGITNVAECV
                     NIGDTNIEELLKFAKENEIGLTIVGPEVPLVMGIVDEFEKEGLRVFGPNKKCAQLEGS
                     KAFSKEFMIKHNIPTAKYKEYTNLEEAISEIDSFGYPVVIKADGLAAGKGVVIPENRE
                     DAIATLKEMMSDKKFGAAGDKIVIEEFLKGIETSILAFVDNDTIVPMASAKDHKKVNN
                     YEQGPNTGGMGTFSPSEIYTEELANKVKETVLEKTLEGFKKDGLNFKGILFVGLMITE
                     DGEKVLEYNVRFGDPETQSVLFRLETDLHEIMETILDNKLKDIEINYSDDEAVCVMLT
                     SGGYPDSYEKGKIITGLENLDDDIVVFHSGTKMLDGNLVTNGGRVIGITAKSTTVKDA
                     AEKVYENIKKINFEGMHYRTDIGR"
     gene            66820..70626
                     /locus_tag="PC366_000058"
     CDS             66820..70626
                     /locus_tag="PC366_000058"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HDF2575622.1"
                     /translation="MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIEN
                     LRILNRYDVEGISEEVYENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQ
                     RGDWAAQCVQIVNQGIRPAINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKP
                     ETLKMETEIPTTVEVLDGFIDLDENGLRTFVSEKGLAMTLGDLQHVQKYFKDTEKRNP
                     TITEIKVLDTYWSDHCRHTTFMTEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRH
                     KDICLMDIATVAVKELKKNGKLNDLDESEEINACSINVDVEVDGKMEKYLVMFKNETH
                     NHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVTGSADPRTTLEDTLPGKLMQRK
                     ITTEAAHGYSSYGNQIGLTTGQVAEVYDENFVAKRMEIGAVIAAVPKENVVRERPEAG
                     DVIVLLGGKTGRDGCGGATGSSKEHSEESILTCSAEVQKGDAPNERKIQRFFRNKEVA
                     QMIKRCNDFGAGGVCVAIGEIADSLDINLDLVPKKYDGLDGTELAISESQERMAVAIK
                     KENKDKFIQLAVEENLEATHVATVTDTGYLRMFWNGKAIVDINREFLDTNGVKQTTDV
                     HVTKVDEENTFFSSNEIVKDVKCASMKDKFTKVLSDLNVCSQKGLVEMFDNTIGGNTV
                     LMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYNPKVGKWSPFHGALYAVVESV
                     CKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLGAFYAQSKFEIPAIGGKDS
                     MSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVMLCVNKAENDVVDFEELK
                     RNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFSEEAEKTFTDDKLFE
                     ASYGNIVLELANDDLCMLEGYNYVVLGSTTKEASIFIKGEELALDELYKAHCSTLEPI
                     FPTKTEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYDSARAFERVGA
                     NANIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKFIATVFRNP
                     RVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNNIGRHQA
                     KIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQYVDF
                     NNEATYDIEFNPNGSFYAVEGITSADGRVFGKMGHSERIGEEVFKNIIGEKDQKIFES
                     GVKYFR"
     gene            70832..71704
                     /gene="rfbD"
                     /locus_tag="PC366_000059"
     CDS             70832..71704
                     /gene="rfbD"
                     /locus_tag="PC366_000059"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HDF2575623.1"
                     /translation="MKILITGSNGQLGKELVSQLEAINQSINQPKYVILATTRNDLDI
                     SNQTNIDNFILHNKPDVIVNCAAYTKVDACEDNIEIAYKINALGVRNLAIASEKVNAK
                     LVHISTDYVFNGFSKYPYREDNKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENKEVNVVNDQFGTPTSTVDLAKIIIRIMETEHYGVYHATCEGE
                     CSWYDFAKKIFELKNIDIKVNPIKSNEFKCKAQRPLYSVLDNFMLKLIGLNSFRKWEE
                     SIEEYLERYDINEK"
     gene            71813..72694
                     /gene="rfbA"
                     /locus_tag="PC366_000060"
     CDS             71813..72694
                     /gene="rfbA"
                     /locus_tag="PC366_000060"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HDF2575624.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGLKITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLENAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYTKGYISREQLMKLAKPLIKTE
                     YGQYLLKLASEDMQYGR"
     gene            72731..73288
                     /gene="rfbC"
                     /locus_tag="PC366_000061"
     CDS             72731..73288
                     /gene="rfbC"
                     /locus_tag="PC366_000061"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HDF2575625.1"
                     /translation="MGKINVIKTKIEGLYIVEPNVFCDERGYFMESYNKKDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVRYPQGKLVRVTEGEVFDVAVDLRKDSQTFGKWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFNYKCTNYYYPEFEHGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFKDICIRR"
     gene            73326..74309
                     /gene="rfbB"
                     /locus_tag="PC366_000062"
     CDS             73326..74309
                     /gene="rfbB"
                     /locus_tag="PC366_000062"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HDF2575626.1"
                     /translation="MKKILITGGAGFIGSNFVHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDSSNYKFVKGDISNREQMYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSPINPSSPYSASKAS
                     ADLLVSSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEIYNIGGHNERSNLEVVKMILNLLDKSEELISYVND
                     RPGHDLRYAIDATKIENELGWKAKYDFDLGIKETVKWYIENESWWKAVLSV"
     gene            74348..75016
                     /locus_tag="PC366_000063"
     CDS             74348..75016
                     /locus_tag="PC366_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HDF2575627.1"
                     /translation="MNEISSLINILALTQLSGSNTTNQCNCTYNSSSGFDMIMMTLLK
                     ALSQNNQQTSNGYNLSSNSENLFDELGSVVNNTASRFIDVDTKDKSVKSRIENAIEQA
                     SKKYNVDSNLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            75025..75453
                     /locus_tag="PC366_000064"
     CDS             75025..75453
                     /locus_tag="PC366_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HDF2575628.1"
                     /translation="MGINIDKLNISPSINMEVKKLKESNKFSDKLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            75477..75791
                     /locus_tag="PC366_000065"
     CDS             75477..75791
                     /locus_tag="PC366_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HDF2575629.1"
                     /translation="MNSKKEDIYELNFGQLIEEKSGVIEENQNVFNAKVNVAVSIGNT
                     TETIKNILDLKEGSIIKLSKNVDEKLDIYANDRLFAYGESIITNEKLSVRLSKIEDSD
                     VN"
     gene            75943..76218
                     /gene="flgM"
                     /locus_tag="PC366_000066"
     CDS             75943..76218
                     /gene="flgM"
                     /locus_tag="PC366_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HDF2575630.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGVKKVEEVKKINKTDKIELSKFAK
                     EMASVSNMSDENIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            76223..76639
                     /locus_tag="PC366_000067"
     CDS             76223..76639
                     /locus_tag="PC366_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HDF2575631.1"
                     /translation="MITDLKVIIYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGDDISMSEVVENSNDRYLKEIYTDLKHILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPADKQTATYNSYGNIRK"
     gene            76657..77967
                     /gene="flgK"
                     /locus_tag="PC366_000068"
     CDS             76657..77967
                     /gene="flgK"
                     /locus_tag="PC366_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HDF2575632.1"
                     /translation="MAGLFSILNTANSGMNAHQKAIQTISHNISNLDTDGYSRQRTEF
                     ATNSPMYMPSLSNSIARGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGNTVSKYDYY
                     NTIETIINEPSDYGISAGIDDFFKGWESLAKDINSDSKKSLVVENASNLATLISESYK
                     KLNKLKGDIDDNINSEIKQINDMLKSLEDLNKSIDVISGSGSTPNDLLDERDRILDDL
                     SFKLDLENSDVKNMLSDGKLELNELKNADGTWKTGVSGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVTDFFITSNVDGEDIIKVNPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAESVGLDSQKVNQDEVNQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            77986..78918
                     /gene="flgL"
                     /locus_tag="PC366_000069"
     CDS             77986..78918
                     /gene="flgL"
                     /locus_tag="PC366_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HDF2575633.1"
                     /translation="MRVSTGMMSSNYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMETYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKMKEIANALNATHEGKYIFSGSNTGVPPVECIDNADGSVSLKFN
                     SSLNLNKLNDSLSMDIAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGDMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKDILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFNVSILDYI"
     gene            78934..79326
                     /locus_tag="PC366_000070"
     CDS             78934..79326
                     /locus_tag="PC366_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HDF2575634.1"
                     /translation="MMKVTLKKGILGFENLKEYELLDIEDNDSLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVVLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDNGC"
     gene            79320..79532
                     /gene="csrA"
                     /locus_tag="PC366_000071"
     CDS             79320..79532
                     /gene="csrA"
                     /locus_tag="PC366_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HDF2575635.1"
                     /translation="MLVISRKKDEAVLIGESIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNIKILKSLK"
     gene            79554..79949
                     /gene="fliS"
                     /locus_tag="PC366_000072"
     CDS             79554..79949
                     /gene="fliS"
                     /locus_tag="PC366_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HDF2575636.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIARAAILD
                     KNTQKAHRELVRVQDIFTELMVTLDQNAGQWAKDMYKVYDFVRYELSRANIRKDIQVI
                     DNVLPVIEQIKDTWHEADKKSKEERSRYK"
     gene            79949..80305
                     /gene="fliS"
                     /locus_tag="PC366_000073"
     CDS             79949..80305
                     /gene="fliS"
                     /locus_tag="PC366_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HDF2575637.1"
                     /translation="MELNLAELDKLSKEELLLMLVDGTVKYTNISKEALLNNDYLKAH
                     NELIRVQNIFTELMTTLDQDAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNQLKI"
     gene            80326..81849
                     /gene="fliD"
                     /locus_tag="PC366_000074"
     CDS             80326..81849
                     /gene="fliD"
                     /locus_tag="PC366_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HDF2575638.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNVIQESKDLYDKYLSVNSPNSIVSEKAYSSTRITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSSEPIVRQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKASYSEMTGELIISRKQTGSSSDINLKVIGNDNLAQQIANDNGIT
                     FANDASGNKVASVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     VTDTEEAVKNMQAFVDDYNKLMDKVYGLVTTKKPKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRGFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKTLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            81852..82187
                     /gene="fliT"
                     /locus_tag="PC366_000075"
     CDS             81852..82187
                     /gene="fliT"
                     /locus_tag="PC366_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HDF2575639.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYIKISSKLGERQEIINSV
                     SEIDRNDFIQLYNRMELIEIDSRIRDILQGQLLEVKKELHEYKLTKQVNTMYYNLNRE
                     KVNIFNKKV"
     gene            82289..83161
                     /locus_tag="PC366_000076"
     CDS             82289..83161
                     /locus_tag="PC366_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HDF2575640.1"
                     /translation="MRVNTNVSALIANNQMGRNVNAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSVQSSNETN
                     TAEERQKIADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTTN
                     NNNEIKVALVNTSSIMSKAGITSSTIASLNADGTSGTDAAKQMVSSLDVALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            83254..85395
                     /locus_tag="PC366_000077"
     CDS             83254..85395
                     /locus_tag="PC366_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2575641.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRSSIESELIIVDTGSTDD
                     TINISRKYTENVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNIDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFEELKENDNSPYTNYQLGKNFIILGKYHEAL
                     YYLEKSYELYSKLESAPGYLITSLVKTYLYLGKHKKCEKLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLRDEAIITLIKIYY
                     KLEKYESVISEYNNIEDMEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YKNIEEVINNIKDDEKEHVYKILCDIEGNYGILNQIRINKCVSIDKCKEILNEEKEII
                     YAYIIKVAFEDKIDLLDIFYEMEYVWIEKYLKYLLALERSFNLVLYKYIISRPNTSDI
                     KKIRVYKAISKVVLESISLSDEKYKEIFYLYIMYSYKYIRYIYRNLSDFELIKFVCND
                     LDKFTIEFKHLLDIKNKVNDANEKLEYIHSMRKLLNEYPFYNKIIKILISELEENIKE
                     SEEFKDLKDSFIISIENMIETGKINDAKSLVDDYSKTFMDDVKILNIKGILYMFENKL
                     DKADFMLKKALSLDVENEDTIYNIEYLKSLR"
     gene            85419..87296
                     /locus_tag="PC366_000078"
     CDS             85419..87296
                     /locus_tag="PC366_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2575642.1"
                     /translation="MNTPIVVNEKSKDIIKDWQYTYTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKNKYEIIIIDNNSSDGTVEWLKGQSDIKSVYNNKNLGFPKGCNQGIE
                     LATGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSIE
                     DMFMFAHKINTSNINLWKYRLKLVGFCMLIKKSVLDNVGVLDELFTPGNFEDDDLSFR
                     MLESGYKLLLCQDTFIHHFGSVSFKENRNKYTDIMYINRRKFETKWGFNPEYSGMIRT
                     DLISKIDDSLEANINVLEIGCGIGATLLEIKNIYKNASIYGIEISESAGKLAKYSADV
                     LIADIEKVKLDYEKDFFDYIILGDVLEHLTDPWKIVNELKQYLKKDGCLISSIPNIMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSVTATSMPLSEID
                     NRFIDTMCKESCKEMRQQYESYQYIVKATKSIDTKRYSSISMVNLKYALMRIDNELDV
                     DSNLSYIFDNYNITEPCFVDDIEYLVDTFVINKATLLNRLGVEAFNRGLGDFSINMFM
                     TVLEMDRDDIDSIYNITSVLCELEEFDTAYNLIKNSSKKVQSESDIQDILYFIEGKRY
                     E"
     gene            87289..89403
                     /locus_tag="PC366_000079"
     CDS             87289..89403
                     /locus_tag="PC366_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDF2575643.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDAFIINKNFIYDILEIFKKNTDVGMIGVAGVKDI
                     PVNGIWWDSDKKAGKVYDSHTGKMDIYEFSNFEECFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIVPKQNKPWCMHDSGVANINNGYDEYRIKFVKEYI
                     NLDLYRENFYEFDKKKASTILKSNKHVMDCMKEELTEQLRLKNYKDVLDIVSKIAHFS
                     VFNHTGLYSCEKCERALLECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPDWLLKAIDDSGGEVISLDLISDDYLKRAVALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGKIPILHVNHYDSTFWLGTSIADIVIDFSE
                     ASQLITLDKRGIDKSEILPMPLKEKEVFSKSEVRKRYNLEDDVTIILTIASERKYNSV
                     NDINYFKIAKTLIENTDNTIIIVVGVDTENLYWKTLSNVTDNRVICFGTTANIDDFYK
                     ISDIYLESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDKFDYKNIKEVID
                     MIRRYNTSEFDRDKIKEKQSEIKHFVIDKHCIEIKNYIDKIYKEANHHKVKYDLYKND
                     EIEDYQLFVALYGYMVKNKNMS"
     gene            89412..90407
                     /locus_tag="PC366_000080"
     CDS             89412..90407
                     /locus_tag="PC366_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HDF2575644.1"
                     /translation="MNNIHINKFEKSCEKNWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIIYKGEEILAVVPACETYENGERVFFSHLGSTFGGIIIRSGFNDIRHVNAIT
                     NKLETYLQEQSFNKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKK
                     DILANFRYSKRRYFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSVEEL
                     LEFKNNRLKDIVEFYAVYIDDIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKDALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            90499..91731
                     /locus_tag="PC366_000081"
     CDS             90499..91731
                     /locus_tag="PC366_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HDF2575645.1"
                     /translation="MKRLMILGSIKYFENIVMSAKKEGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKSIAIDKKIDGILTGFTDSLMKPYVYIANELNLPCVISCNQLESVT
                     NKAIMKKYFKNNAIPTTDYCIIESLKDLEKIQGLNFPLVIKPVDGYGSRGVYFVSNIE
                     ELIEKFEYSKEASQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLLYPSKYCFQYEEEIKSIYQNITQAFDIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEVNFDEIKKYNMHLSKCVYALPIYIRPGTI
                     KKINNIDKIENLDYVTQFLLLVKEGDTIGLYEDERQDCGRVYGIANNIFDANIKKKCI
                     HEMIEIFDENNENMIENF"
     gene            91751..92695
                     /locus_tag="PC366_000082"
     CDS             91751..92695
                     /locus_tag="PC366_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HDF2575646.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVEE
                     GHVFYNVMPSLNHNHMIGGIKMVTRLPGRNPSLNSDIFLYNMKDAKLKAILDGNYITA
                     FRTAAVAGLAIDTFAKKDFNTISIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ESFIKKYEKNEQFSFEICDTHEELIVDSDVVISTVTYTDEYLSEFKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYNVLSKQAKGRENDDERIISY
                     NIGLSIHDILFANKIYELCETLNCEEIELKEPKEKYWI"
     gene            92789..93196
                     /locus_tag="PC366_000083"
     CDS             92789..93196
                     /locus_tag="PC366_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FdtA/QdtA family cupin domain-containing
                     protein"
                     /protein_id="HDF2575647.1"
                     /translation="MDKYNLIKFLSIGNEYIGNLVALESNKAIPFDIKRVYYIYDVPN
                     NVKRGFHAHKNLEQVLVCLNGSVKIKCYDGVKESIFNLHKNDVGLYIGTGVWHEMFDF
                     DEKTVLISIASEHYNEEDYIRDYKEFLKYLNNM"
     gene            93283..94374
                     /locus_tag="PC366_000084"
     CDS             93283..94374
                     /locus_tag="PC366_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HDF2575648.1"
                     /translation="MLVKFNNLLKQFQTHKEEYEQKIKDVMESGYYILGNEVRHFEEE
                     FASYVGSKYCVGLASGLDALIIAFRALGISEGDEVIVQSNTYIASVMGISINGATPVF
                     VEPNEYYNIDSSKIEEKINSKTKAILVVHLYGQASKMKDIQELCDKYNLYLIEDCAQS
                     HGAKYDGKMTGTFGDIGCFSFYPSKNLGAFGDAGAIVTSNEEIADKVKILRNYGSEKR
                     YYNKFVGYNSRLDEIQAGLLRVKLKYLNEIEIEKSKIVDRYLNEINNPKVILPKIENN
                     CTHVWHLFVLQVEKRDTFMEYLKKNGIESIIHYPIPPHLSEAYAYLGYKKGSFNIAEN
                     YSDKVVSIPLFVGMEDEEVSYIIKIINEY"
     regulatory      94683..94773
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            95180..95497
                     /gene="flgB"
                     /locus_tag="PC366_000085"
     CDS             95180..95497
                     /gene="flgB"
                     /locus_tag="PC366_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HDF2575649.1"
                     /translation="MNTYDIIKMGLDATNLRSQTIANNIANINTEGYKRHYVTFEETL
                     NDAMPKIEEKTDNSKGLRVDGNNVDIEEEKVNQAMATLQYNALISFANGKIAMTKSII
                     SGR"
     gene            95505..95909
                     /gene="flgC"
                     /locus_tag="PC366_000086"
     CDS             95505..95909
                     /gene="flgC"
                     /locus_tag="PC366_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HDF2575650.1"
                     /translation="MSVFSGMRISASGLTAESLKMDIISSNVANINATRGPNGEAYRR
                     KVVSFEENYDNKLGMLGVKVTSVEDDKSPLKEVYDPSHPDAKPNGYVEYPNVNILVEM
                     TDLITASRAYDSNVDTLNAQKSMISKALEIGK"
     gene            95919..96236
                     /gene="fliE"
                     /locus_tag="PC366_000087"
     CDS             95919..96236
                     /gene="fliE"
                     /locus_tag="PC366_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HDF2575651.1"
                     /translation="MPITQINNLMQGAKLDNLIGETKPLTLNNKEEKKNFEDVIIDTI
                     DKVNFQQVTADDMKEKFIKGEDVSMHEVMLIGQEAQLSMQYLIEVRNKIHDAYQEMNK
                     VQI"
     gene            96261..97811
                     /gene="fliF"
                     /locus_tag="PC366_000088"
     CDS             96261..97811
                     /gene="fliF"
                     /locus_tag="PC366_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HDF2575652.1"
                     /translation="MIASFKNKIKEQVAKSRTKISSLKKGTKIALGIGVIAICLALVF
                     TAISASKNKYAVLFSELDVQDAADISAELESKKIDTKVKGSTIYVPRTEVDKLRLELA
                     PSLTGGSKGFALMDDSSSIGLTDEEFQIKKQRMIQGEIEKTIKSFPQVEDTRVHITFG
                     ESSVFEKEAIPGSAAVYLMLKPGTTLEKNQIKSVMALISGSVTNIPEKNVQVIDNKMN
                     LLSEGILEDEDVDENNQPTNSLINVDKNKASEQALNKQLEKSILEMLEPIFGKGKVKA
                     TVNADLSFDTAEKTEIKIDPDKVAIKETRSKNSSKSATNNVQGVDANMNNQGNNNGTN
                     TEDSLDESFEYETGKIETHTIVAPGELNRLTASVAIDGKIAKGVQADVEDIVNNAIGM
                     DGARGDTLSVVSMVFDPEGKAEAKQELEEIKKEGFKKNIIKAVIGVVAVVAIGAIGYL
                     IYKKRSEREDMDYEDEDYISKSDSVDRKDNPLLGDDPELTLEEAVKMYAEEKPDQVTE
                     IIKTWLNE"
     gene            97824..98894
                     /gene="fliG"
                     /locus_tag="PC366_000089"
     CDS             97824..98894
                     /gene="fliG"
                     /locus_tag="PC366_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HDF2575653.1"
                     /translation="MSTEITNVNAFDLSDINESDKKEKIEGEGLKKAAVLLMTLGPNV
                     SSDIIKSLPDKQVQKIGLEIANISSIASKERREILKEFVEINRAKDYVIEGGLEYARE
                     LLSNALGNAKANKLLEGISINTSTKPFKHIIKLDVKKILEILRDESAQTIAVLLAHME
                     PENGAEVLSYLDFDLQNEVAMRISSMGSISPEVIKVIESSLEDKLHSISGDDFKDYGG
                     VSTLVQILINSDRKTEKNILGTIEEQDPALAAQIKSHIFVFEDIVKLDDISIQKVLKE
                     VTMKDLVYALKGVDDEISDAIYRNQSSRAADALKEEMEMVGVIKVTQVEAAQQKIANI
                     VRKLEREGAITIVRNFGGDFVE"
     gene            98887..99618
                     /locus_tag="PC366_000090"
     CDS             98887..99618
                     /locus_tag="PC366_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HDF2575654.1"
                     /translation="MNNKIIKSKKASYKGVLDLTIIDKVRVGESNVNKENDCRFRDEV
                     IKEAIESAEIKKNEILEEAKMNAQNIEKQAYEKGYSQGQKNGYEDGYKESYDEYTQKA
                     KDEADFIKNQADLILLQANEKMTEYIKEKNKEIVRLAINMASSVLKKHFEDEESMSDL
                     LKQIIQDYEGSSSFIVRCNSFYKDNIEKEFELFKEETSLKSSVFVIADDSIDKGNAII
                     QKENGRIIVGIDCAMEKLKEELLGE"
     gene            99622..100941
                     /gene="fliI"
                     /locus_tag="PC366_000091"
     CDS             99622..100941
                     /gene="fliI"
                     /locus_tag="PC366_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HDF2575655.1"
                     /translation="MYKTDISIDFDKINKKIENLELTISEGRVKKIIGLTVEVEGIKA
                     FVGELCVIYNQVNKPVNCEVVGFKDKEVILMALGELTLIAPGCKVISKGIPLSVMCSD
                     NLLGKVLDGLGNPIDNSDAVLGDRYNLNNEPPDPMKRKKIRNIMETGVRAIDAFTTCG
                     EGQRIGIFAGSGVGKSTTLGMIARNAKADVNVIALIGERGREVLDFIDKDLGEEGMKK
                     SVVVCATSDKAPLVRLKGALTATAIAEYFRDQGKKVILMMDSVTRFAMAQREVGIAIG
                     EPPAQKGYTPSVFAILPKLMERTGTSDKGSITAFYTVLVDGDDFNEPIADTTRGILDG
                     HIVLSRDLANKNHYPSIDVLNSLSRLMNEIASKEDIKIASFARDMLAEYREAEDLINI
                     GAYASGTNKKIDEAIYYHEHIINFLKQGINEKSSFNETISSLRRIFE"
     gene            100973..101419
                     /gene="fliJ"
                     /locus_tag="PC366_000092"
     CDS             100973..101419
                     /gene="fliJ"
                     /locus_tag="PC366_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HDF2575656.1"
                     /translation="MELDKNFKFRLQKVLDLKIKDEEEIKMEFAKIQQKKIDIESNLE
                     NLESNYSKYSISKNNDSVQNQKITINYLLALNNSIMDLSEELDKSTNELEKARKQLIS
                     KQIERKSLEKLKEKKYGQYYKEEQLKEQSTNDEFASMSYLRNRQVL"
     gene            101447..102652
                     /locus_tag="PC366_000093"
     CDS             101447..102652
                     /locus_tag="PC366_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HDF2575657.1"
                     /translation="MKIQADSYNIIKDIGNRKSSSKNKNIKNNKFEDNLYKATDHKKV
                     KDRRETSKQNVSSDKRENSDNECHLDEDKSNHLEDENTYEKDCSNNNEALHQLLNLLK
                     DNYKKDKDINTILNNLKKLSISDELKQELKLNKNILNKIANQNLELNRASTNNPNDIE
                     NLDIMKLRELLENNASEDIEVISKTTENDTKSIDLYSFDSNRIDTLNSNKQKDDSSDI
                     LEKLAGVNGNKSGNFGQVINKSVDMNKIKNDNVNLKQIESNVMDDSIKAIKHMKTNDI
                     QELTIKLRPKELGDMNIQLLKDGESMRAVVTVFNKDVFDSINKNIADLKQHLELTNVN
                     IKDVSVQMHSDNTNTSDTFDKAFEQQNRQNNQENMSKQNTNDKRNNVVIEDEIKENII
                     DDDRVDLLA"
     gene            102670..103278
                     /locus_tag="PC366_000094"
     CDS             102670..103278
                     /locus_tag="PC366_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlgD"
                     /protein_id="HDF2575658.1"
                     /translation="MYGIATALAGTQVNYRSNNLSQLERNINDIANKQVRSKGNQTVT
                     DNGTPIIGQGDDADKDLFMKILVAQMGNQDPMNPQDPTEYVSQLAQFATLEKMSAMND
                     KLDILLALSNSTLINSALSMATSLIGKEVEVSGEEEEDENIVGVVKSTYIKDGEVHLE
                     LEVDGSDKTVGVKYEKLLKIGEVDANSGEENDSSEQESPEEV"
     gene            103305..104288
                     /locus_tag="PC366_000095"
     CDS             103305..104288
                     /locus_tag="PC366_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HDF2575659.1"
                     /translation="MIKAMYSGVSGMKANQTKLDVIGNNVANAGTTSFKKSSARITDS
                     FYQTVLYASAPTAALGGTNLGQVGVGSKISSINKDMTQGNVQPTNRPSDLMIDGDGYL
                     PVVRQGTVMYTRDGSFNLDTGFKAADGALKNIKGGRLVNGDGYMLQGVIYDGEYKADT
                     GEFIKKGDAKGKEPIVIPLQSISPKDGTVQNVLEYNISKDGTVEFLLSDGQRTQFVYD
                     IPDGAKVGDTPAGIDKLKGTIQKVQTYAFQNPAGLDAEGGNLFKPSANSGDPQIAGAT
                     GNIIQGAIEASNVDIAEEFTEMIIASRSFQANSKIISTSDEILQEIINLKR"
     gene            104301..104504
                     /locus_tag="PC366_000096"
     CDS             104301..104504
                     /locus_tag="PC366_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FlbD family protein"
                     /protein_id="HDF2575660.1"
                     /translation="MIRVTDLNGRRYILNSDLIVRIDSVPESRILLTTGEKNLVKESV
                     DEIVDKVIKYKRKVNVGYIRSEK"
     gene            104504..105322
                     /locus_tag="PC366_000097"
     CDS             104504..105322
                     /locus_tag="PC366_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HDF2575661.1"
                     /translation="MKKTDSLTFIGLILSTVLVLFGAVKGSSSGLKSFFDFASILITV
                     FGSFGALMITFTIDDIKLIKDALQYSFKTMNISKLDLLNQFKTLSKKARREGLLSIES
                     DVMKIQDPFMKKGLELCIDGLEVNEIRSILELEIDSVEETNNRYSKLFKTWGTFAPAF
                     GMLGTLIGLIQMLSDLTSPDLIASGMGKALITTFYGSLLANIALNPIAYNIDEKTEKE
                     IYVKEMMLEGIISIQSGESSIVVEERLATYLSNNEKLEIMKSNKNTERAMSNGA"
     gene            105312..106007
                     /locus_tag="PC366_000098"
     CDS             105312..106007
                     /locus_tag="PC366_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDF2575662.1"
                     /translation="MARKKNKKKDEINPDAWLATYADTITLILTFFVLLYATSVVDME
                     KFKNIADALKGQFSGISMFSTGSSTSEKSPIESVLVDKNDKSNLEQDLKDKVNNSNLQ
                     NSVTVKDDSRGILLELDDSILFDSGISELKADSKATLNKVYDMIKMMKNKIVIEGHTD
                     NVPVKSSTHESNWDLSSSRAVSVVRYFVEEKGMDPRLFSATGCGEYQPLVSNETAKGR
                     AENRRVNILITID"
     gene            106019..106462
                     /locus_tag="PC366_000099"
     CDS             106019..106462
                     /locus_tag="PC366_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HDF2575663.1"
                     /translation="MFKNKKIIIIILILIIFSAGAGFFILGEGGNKQIDKIAGLFIPT
                     GKGKDEVKTENLDLEEMVLKLADEGVRYLKVSITVSYDSSYKDIEKNTPLIRDNIINC
                     FMAKRADDFTADNLKNIKEEIKNTLNIQLGENVIQNIYFTNIVVQ"
     gene            106477..106851
                     /locus_tag="PC366_000100"
     CDS             106477..106851
                     /locus_tag="PC366_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliO/MopB family protein"
                     /protein_id="HDF2575664.1"
                     /translation="MILYLLKILICIPIILILIVLSLKISQGTLLKKYNDKYIKILDI
                     VNISKNNSIIILKIGEEGCIMASSSSSMNKIKDLTKEEILRIENDIKERNFKIQDFKM
                     ERIKKKYDFSRYIGKFTKKEDK"
     gene            106852..107517
                     /gene="fliP"
                     /locus_tag="PC366_000101"
     CDS             106852..107517
                     /gene="fliP"
                     /locus_tag="PC366_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425215.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HDF2575665.1"
                     /translation="MELLSKLPLADVPYTSSMQLFLFLTALMFLPFVMFMMTSFVRIV
                     ISLSFLKSALGAQQAIPSQILVGLAIVLTIFIMRPVLNEINEKALQPYMKEEVTMEEA
                     MKEAEGPIKEFLLKQTRQTDLDLFVEQAGLKEKKLTRENIPLSVVVPAFAISELKTAF
                     QIGFLIYIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLFVMVDGWNLIVKTLIL
                     GFG"
     gene            107530..107799
                     /gene="fliQ"
                     /locus_tag="PC366_000102"
     CDS             107530..107799
                     /gene="fliQ"
                     /locus_tag="PC366_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HDF2575666.1"
                     /translation="MSEFMIMSVLKNGMFTGAMIAAPVLIVSLVVGLLISVFQATTQI
                     QEQTLTFVPKLIAILLVVAIGGSWMLHTLISFTSEIFNMMSLITK"
     gene            107811..109625
                     /locus_tag="PC366_000103"
     CDS             107811..109625
                     /locus_tag="PC366_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused FliR family export protein/FlhB family
                     type III secretion system protein"
                     /protein_id="HDF2575667.1"
                     /translation="MIFVFIRIVAFFGTLRILFPAGTPALFKSLFAIIISILISSTMQ
                     IEYATNIDNIVLFTLYGINETITGIMLGYITNLCFYSIRMAGSMMDQQMGLSMINMFD
                     PNSMTQTTLIDNLMNWTARMIFFSMDGHHVLIRGIRYSFELIPIGKSFVDNNIDYIIN
                     IFVQCFLTGFKIAIPIVLCLLMADFILGLISRSVPQLNVMIIGMPLKILVGIALFIIS
                     IPLIVNQISHLLSQIPKMYEGTFALAPMFFMGSTDKTEEATPKKKGEQRKKGNIAKSK
                     ELPVAMTLLAFTLLVPTLFSYVVDTLKSSLNYFLSLDFYMNINYSSIEKLVIAGLMDF
                     FKIFLPIAIPFLVLGIVANLFQVGILFTGETLKPNLSKLNPVSGFKNMFSMRSLSTLI
                     KDTAIISILAYIGYTFFQDNYLDILKLGNIYLPTLMYTVKDLVYSILSKICVAMIVIA
                     VADYVYQRYSHKKQLRMTKQEVKDEYKNSEGDPEIKAKIKQKQRQISSQRTMQAVPSA
                     TVIVTNPTHLSIAVRYEKGKDQAPVVVAKGADYLAFKIREIAKGNDIPIIENKPIARL
                     LYKQVEIDQEIPEDMYQAFAEILVAVYKIKNRYKVLKR"
     gene            109634..111709
                     /gene="flhA"
                     /locus_tag="PC366_000104"
     CDS             109634..111709
                     /gene="flhA"
                     /locus_tag="PC366_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HDF2575668.1"
                     /translation="MNKFNLKENMDVIVAFGVVGIVLMMIVPLPTFILDILLAINISL
                     SVLILLMTLFTTNVLDLSIFPTVLLVTTLFRLGLNLSSTRLILTQGYAGEVIEAFGSF
                     VVGGNYVVGIIIFLIILIVQFVVITNGSGRVSEVTARFTLDAMPGKQMSIDADLNAGV
                     IDDKTARKRRKELQQEADFYGSMDGANKFVKGDAIAGLIVTAINIIGGIVIGAVMLNM
                     TLMGAAQTYVRLTIGDGLVSQIPALLISTSAGIIVTRASTDENFGGLVSKQLTAIPKA
                     VMMTGCVLIVLGMMPGLPKPAFFSLGIGAIAAGYFLGREKKDTLEDLEFEKPDMVNPD
                     KNEVEDVTNLINVESIEVEIGYGLISLADESAGGDLLQRIASIRRQCAIDMGIVVQPI
                     RIRDNLQLNPNQYNIKIKGNVVGGYEIMPNMVLCMDPMNQGFSIFGIKTIEPTFGIEA
                     LWIESDKVEDAEIKGYTVVDSSTILITHLLDIIKSNAHELLGRQEVKTIIDAARENYS
                     AVVDELIPDLMTLGEIQKVLKNLLREKVNIKDRVTILETLADQSRNTKDIELLTEYVR
                     IALARSICNNLVDDDKTIVVATLSPETEELVSNNLQRSVNGTYPAVDPENTNKIFESI
                     QEVMNNVYFNHNIPVIVVSPKIRAPFRKLVEIVYPNLTVLSLNEIPNDIKIKAEGVVS
                     IYDDEKVYS"
     gene            111684..112700
                     /gene="flhF"
                     /locus_tag="PC366_000105"
     CDS             111684..112700
                     /gene="flhF"
                     /locus_tag="PC366_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HDF2575669.1"
                     /translation="MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIQGIFS
                     KKDIELTIGWEKRENVEQKDLKREIEQLKLIINNMGFDNKNDNDIDKICKNLLSLELN
                     EEIVESIRIDLQEMKFNGIDTSKNLVEILKKKIKIENQAINGKIALVGPPGVGKTTTI
                     AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEM
                     KDCDVVLIDTTGRGYKNSMQILEIKNLIDKAETDNIHLVVNCTTRESDTKAIIDSYRN
                     VNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLG
                     VESI"
     gene            112697..113575
                     /locus_tag="PC366_000106"
     CDS             112697..113575
                     /locus_tag="PC366_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HDF2575670.1"
                     /translation="MIDQAQILRKMAMEKRGLDEFIVENENVPKIITIASGKGGVGKS
                     NLATNLSICLTKLNKKVLILDADIGMSNIDIIMGVNVKGTIIDVINGEKNIEDIISQT
                     KYGVNIISGGSALNHIEDFTEAQRNKFIHSIEQIHDVDFIIIDTGAGMSKSLLSFIYC
                     STEFFLITTPEPTSLTDAYSLLKAISNFGIKRSANIIINRVIDLEEAKSTYKRIKMVV
                     DKFLNLNLELYGYIIDDKKVSLCVKKQIPFILEYPTSIASKCIIAIAKRMVSQSREDI
                     VDNKSFLRKMFSIFKS"
     gene            113589..114290
                     /locus_tag="PC366_000107"
     CDS             113589..114290
                     /locus_tag="PC366_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliA/WhiG family RNA polymerase sigma factor"
                     /protein_id="HDF2575671.1"
                     /translation="MNREELIKENMPLVKSIARKFFIPGKGFEYQDLVNSGVIGLIDA
                     INKFDAEKGAKFSSYSYIKIKSAILDEIRNQSPISKHNLTKVNKYNRVVEKLQSKLLR
                     EPTSYEIAKELNVSEKELHDIESNIDMLNIVSLNYVIFEDTNETVQDVISDREEEAPE
                     NIIEEEEKLEILSKAISNLNEREKLILSLYYYEDLNLKEIGKVLGVSESRVSQLHRKS
                     IRNLRNKIKELKYSI"
     gene            114306..114728
                     /locus_tag="PC366_000108"
     CDS             114306..114728
                     /locus_tag="PC366_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HDF2575672.1"
                     /translation="MIQIILIVVSILIIVTIVINLHKESKNKDNRYFDKIFEQEYEAN
                     DRLIIAEKRRFFLDKVLAEIRSNNHIKVYENYNLIKANEERKENIFIESKKEVRQENE
                     LSLKVKHLISSGYDDVEICKMLDIGKGELSLIRSCYKI"
     gene            114713..114898
                     /locus_tag="PC366_000109"
     CDS             114713..114898
                     /locus_tag="PC366_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HDF2575673.1"
                     /translation="MLQNIRILLCDKKVFLGIGIGILISTLCIMLFSNNDMSKAEIEK
                     KARALGMKYTSEMKVLE"
     gene            114939..115712
                     /gene="flgG"
                     /locus_tag="PC366_000110"
     CDS             114939..115712
                     /gene="flgG"
                     /locus_tag="PC366_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HDF2575674.1"
                     /translation="MIRGLYTAVSAMITNQQKQNVVVNNLANMDTNGYKSKQLLTKSF
                     DELKLEGYNNYANGTKQKQIIGDISPGISMDETITNFNQGPIKTTDNKMDVAIQGKGF
                     FLVSDAAGNQFYTRNGNFRTDNQGDLITSEGYYVLGTNTATGAVGHINVGNQKFEVAK
                     DNTISLDGNAMYKFNIVDFNDYNNLKKEGDNLYSGGGAMKVNNALTIQSAIESSNVDM
                     VSEINNMMTISREYEANQKIIQAMDSKLAKIASEIGSVR"
     gene            115733..116494
                     /gene="flgG"
                     /locus_tag="PC366_000111"
     CDS             115733..116494
                     /gene="flgG"
                     /locus_tag="PC366_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HDF2575675.1"
                     /translation="MYTMFYTSKTALSANQSKLDIISNNIANSDSTGYKKINMEYSDL
                     VDEVLNRPSYPTNGNDISTGTGAKATAPMRIYEQGALAPTDSKSNLAIDGEGFFRVIR
                     KDGTYAYTRNGGFNIDGLGKIVDDNGNILDVQFDAGYNYNNTNIDSTNLTVSRNGELF
                     VDNKKIGKINLYQPIGTQNFISEGDSLFVATDAAQIKQVEKVDIVQGYRERSNVSLQE
                     EFVDLIATQRAFQMNSKGIKTADEMWQIANNLRAK"
     gene            116517..117398
                     /locus_tag="PC366_000112"
     CDS             116517..117398
                     /locus_tag="PC366_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HDF2575676.1"
                     /translation="MNDMKEYDFGKPQSYSRENLTCLNFLLAEFCKKYKNYIIYELKC
                     NSSMIVDSIDQVNYQTFLDRVTSSCVVVQNAMEPVMKNFSFRIDRSVADMWIDITSGG
                     TGVIKDNDRELTELDKKVLLHLMDDLVRNMHLFEGFENIQVLDTHTHINLPQLCSPTA
                     PVCVVDLKVLNDNEYIGSVSLCFPYNGLEALLESISVIEFFDNDVGDDSEEFTKKIYN
                     SVSNIELSVIAEIGKVSINVEDLLKLEVGDVIVTNKKINDYIDIFVENSKSYTATPGF
                     ISSKKGVKINDAVGKEV"
     gene            117401..117775
                     /locus_tag="PC366_000113"
     CDS             117401..117775
                     /locus_tag="PC366_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HDF2575677.1"
                     /translation="MDNSNLISDEEAKMLLNDKVESEVDGDDELALDVSEVNRNNIQR
                     ILDLKLELSVVIGRTKMTLRDILNLHKGSLIELNTLADQDVEILIDNKVLAYGKVVVV
                     DLNFGVKITSIVSEEDMVKSLV"
     gene            117807..119210
                     /locus_tag="PC366_000114"
     CDS             117807..119210
                     /locus_tag="PC366_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2575678.1"
                     /translation="MVLILNLNDIKKDILKLNKKDSCSLYNESINNINNNCISTGLKF
                     LKQARDLNPDDVDILNLTGLVNLLKCNFDDAVESFYKSSLCEKTALCEKYINMLTSEE
                     FLIFFEKYNQLIRLINKGMYKEAIQGFKLITDQYCDLIEPYELLALLYDKEEEYIKFD
                     ECLEVLKIIDKENYLLNQENNTLDMYNSANIQTKSNVKVDDYKNEFLHKSSSNHKIND
                     YNNVTKEKSSSKNQKSSDSNKKKSIKKNKYLYIAIILGILLVGQSIYSSYKMNNLTDK
                     ISKNNETKNEESIDSNLTKKENNIEENEDMSKASNINKSNKNINKEADVKSKKNTVEN
                     EDDKDSDLFTEDELMSKANTLKSEKKTKSSIQLYKKVADIGENKGNTSEATYQVAILS
                     EKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLGMMYYNNGDLKNSKLTLKKLVNKV
                     PNSMYNNSKVKEILKEE"
     gene            119326..121263
                     /gene="htpG"
                     /locus_tag="PC366_000115"
     CDS             119326..121263
                     /gene="htpG"
                     /locus_tag="PC366_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HDF2575679.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDARNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEIVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITIQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKEAVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLLIEL"
     gene            121651..122781
                     /locus_tag="PC366_000116"
     CDS             121651..122781
                     /locus_tag="PC366_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF2575680.1"
                     /translation="MNFNYNLPVNILFGRGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKSTGCDCVLGLGGGSIMDA
                     AKSIAFSYKNPGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKASIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPLADVQAIYG
                     IELISENLIKVYNDVNDLEAWEKITLASTIGGMTIGTAGTALPHGMEHPVSGLRDVMH
                     GKGLAALTPTIIESSWDIDIERFGNISKVLGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVANIKRHPKYFNKEQIKEMYHKSL"
     gene            123008..124030
                     /gene="splB"
                     /locus_tag="PC366_000117"
     CDS             123008..124030
                     /gene="splB"
                     /locus_tag="PC366_000117"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HDF2575681.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKKIYNKFRDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GREEKGRFRFVTKYSDVDSLLDAEHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIISIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFLKEINGVFKNS
                     LIKYII"
     gene            124212..125123
                     /locus_tag="PC366_000118"
     CDS             124212..125123
                     /locus_tag="PC366_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2575682.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VESGTSVEGYNTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTD
                     FAIEMYYPTTPEAAYLEHWIVPVPIEQ"
     gene            125138..125554
                     /locus_tag="PC366_000119"
     CDS             125138..125554
                     /locus_tag="PC366_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HDF2575683.1"
                     /translation="MNWQDAFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVSESNRVEVDLFINTCCDYIK
                     KIYNEVNFFNGSKWLMIQVDSLLVLNDMLELIKFRA"
     gene            complement(125648..126040)
                     /locus_tag="PC366_000120"
     CDS             complement(125648..126040)
                     /locus_tag="PC366_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2575684.1"
                     /translation="MSINTEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESTGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNTCGLSCKECRKIK"
     gene            126181..126576
                     /locus_tag="PC366_000121"
     CDS             126181..126576
                     /locus_tag="PC366_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDF2575685.1"
                     /translation="MKALEFLNKAGVYYLATVDENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
BASE COUNT        49998 a        13839 c        22197 g        40716 t
ORIGIN      
        1 aatagtataa aatattattg aattttttct ctcgaaatat ataatttaga atcttctgat
       61 ttatttttat gctcgatttc cttatttttt ttcataaata tatatagagg agctattaac
      121 aacattgccc ctaatcctat taagactcta ttttgagtta taggttttga aatatcttct
      181 gcccaagctt gttgtaacaa ccataagcta cctaaaatag ctaccattgg tataacagga
      241 ccaaatggaa tcttaaaaga ggccttaaca tctgttcttt ttcttaaaac tattactgat
      301 aaacaagttg gtatgtactg agcaaatctt gcaattacac tcattactgc aagttgttca
      361 aaacttccag ttagcacaag tggtatacaa caaattaaag atattattat tgctacatat
      421 ggagcaccat atttatttgt ttttcctata aatgcaggaa gagaaccttc ttctgctaga
      481 gaagaaccac atttaggagt tactattgat gaacctatat ttataccaaa tatagatatt
      541 aatgttgcta cagatatgaa aactttacca taattgccta aaaatacact tgaagcatct
      601 gcaattggaa tactgttttc aaatagtcta tctccaagta tacccataca gacaatttga
      661 attaatatat aaattattgc acatataaat attgtggtta ttaatgcgat tggaagattt
      721 tttttaggat tttccatttc tccacttgcc acaataaatg attcaaagcc ggtaaatgcg
      781 taaaatacta atataatggc tggacccata ctagagttaa ctacatttcc tgaaggaaca
      841 atatttacaa attttataaa gaatattcca actatcacaa aaactattaa tggtactaat
      901 ttagctatag ttattacatt attcattatc tttgtgcttt taattccaaa taagctattt
      961 attgaaagta gtgttacgag tattgcagct atacaacctt tgtattcagt ggcagattct
     1021 ggccaaaatg aacctaaagc tgttgcaaat cctactgcta gagtagacca tgatataatt
     1081 ctaataaacc aagacattgt accaacttca aatcctataa aatctccaaa agcttttttg
     1141 gagtatagat atgctcctcc attcttatca aacatgcttc caacttctgc aaaacataaa
     1201 agtattgata gaactaagag tgtagcaaaa atgtatataa acatactgtt ttgacctgct
     1261 agactataaa ctttacctgg tagtaagaat atacctgaac ctattatgct attaatccct
     1321 aataatatca tactaaatag acctaatttc ttagcttttt ccatattaat ttatctccta
     1381 ttcttttatt aattactgta ctaattaaaa tacaaagtat tcattacatg catcataaca
     1441 cctattggta aacaatcttc atctatattg aagctagagg tatgaagagg tgaaattaag
     1501 cccttttcct catttttaca tcctaaatgg aagaatgctc ctttacaatg ttctgtgtaa
     1561 aaagaaaagt cttcaccacc taaagacggg tttggtctca atataaattt ttcctctcca
     1621 agtaattctt tagtacttga tataactgta tctactaatt ctttttcatt tataacagca
     1681 ggatagtttt catcacttac atgtaaagtc ccaacacaac caaatgcaga tgcagtgtct
     1741 ccaacaattt tagctatttt atcaatcata aagtttcttg ttttgctatt taaggttctt
     1801 aaagtgcctt ctagttttac atcttcacat attacattgt gtgcatcacc accatatatt
     1861 ttacctatag tcaaaacggc agcattattt ggttctaagt ttctacttat tatagtttgt
     1921 aatgatgtaa caatttgtga agctgtaact attgcatcaa taccattttc aggatatgca
     1981 ccatgagctc ttttaccttt gatacttatt tttatagtgt ctacactagc atttaatgta
     2041 tcatattttg tttcgataag gcctgtttct atatgtggca taacatgaag tccgaatata
     2101 taatcggcct tggggttttc taaacaccca tcctcaacta aaaattttgc tcctccaaaa
     2161 ccttcttctg ctggttgaaa taagaatttt acatttacat taagtttatc ttttattgaa
     2221 tgtaaaactt tacatgctcc aagtagcatg gttgtatgtg catcgtgacc acaagcatgc
     2281 atttttccag aatgtattga tttataaggt atgttgtttt cttcttcaat aggaagagca
     2341 tccatatctg ctcttataca aatcgtttta tctgcacttt cttttaaaat atatgccata
     2401 attccattgt gttttgtaaa ttccatataa tcaattccga tttcttttaa ataagaaatt
     2461 accttctgtt tagtaagatt ttcttcaaga gctaattctg gaattttatg taattctctt
     2521 cttatgttta taagccatgg ttttatagaa ttacaacttt ctattacaaa atcttttcct
     2581 aattctttgg tttgatattt taatttcaaa gcctgttgca tttttattcc tccaattgct
     2641 ttttattgtt ttattaatat aataagcaat tattatgcca taattttcga tggagaattt
     2701 tgttttttat aagaatattg aataaatata atcatttatc tatatgtata gtataaaaaa
     2761 tgattgcata gtttcaattt tcagtaaaaa atattatttt gaagaaaata tattttatat
     2821 gctagtttat ataaaaaaaa taggaaataa aaaaattatc ctattcctat taattcctat
     2881 tatttatgta caaaataaat tataatttta gggtacttga aaaataaaaa aacctattga
     2941 aggagtactt taatcctgaa tagatttctt tgtttgataa attataattt tatagacctt
     3001 tatattttaa tttattgtaa aaatcttctc ctttttgagt tattttactt ccatatcttc
     3061 ctgaactaca aattataagt tcttcttttt ttagatattc aaatattttt ttaatttttc
     3121 cttctgtaat ttgaaggttc ttatcgagta gtgcttttaa aattaatccc ctaccaatac
     3181 caacatctga ttccttattt aaaattagta tctctaatat attcaatata tcattcttac
     3241 tatattttag ttttaatgat gtatttttgt tatctgaaga ccttaagttt ggaggtaaat
     3301 ctttctctaa tacaatatct tcacacataa tgtttaaata ggatgtaaca ttttggagtt
     3361 ctcttatatt acctttccac atatagtttt gtataagttt ttttgcttct ggtgtgatta
     3421 ctaatttctt attaattaaa tcttccataa taattaatat gtcttctttt ctttctctta
     3481 gaggaggtat atttattgga attgtattta atcgataata taaatcctct ctaaattggc
     3541 tattatcaat catttgttct aaattcttat ttgtagcaga tatgattcta acatctatat
     3601 taattacatt gtgagaccca acaggcatta tctgcttctc ttgaagaact ctaagtagtt
     3661 ttgtttgtaa ttctaaaggc atatcgccta tttcatctaa gaatattgtt ccattattag
     3721 caagttcaaa taatccttgt tttccatctt ttagacctcc agtaaaagtt cccttgtcat
     3781 atccgaatag ctggctttct aataaatttt caggaacggc tgcacaattt actgctataa
     3841 aaggttgatt ttttctattt gagttgttat gtatagactg agctatgagt tctttaccag
     3901 ttccactttc acctctgata agtatgctta agtcagattt agaaaccttc ttagctaaat
     3961 ctatacattc aaacatttta ggactatttg tttttatatc cttaaatgta tattttgcta
     4021 tttgtccttt ttctcttaat tttttagtga gattttgttc taattttttt atgtatgtta
     4081 tttcttgtaa actataatat gtgcccattt tttcatccct attgtatatg ttttttttat
     4141 ttacatttat atatttctta ttgaatacga caactttatc tagtatctct ttctcactca
     4201 ataaaacttt taaactatct acaaatatat catcaatgta ttttccatat atatcctcat
     4261 ttatgtctaa aatatctttt actttactat tatatgtatt tatttcacca tcttttgaag
     4321 taaataatat accatctttt gataaattca atattgtatc taattcttct atttttaaaa
     4381 ataattcctt atatttatct tttataccag tatctaaact tattatttct tctgagtatt
     4441 taactagatt agattgtatt tcctttgaat caatttgtaa taaatttatt atttctataa
     4501 atgtagaaat atctatatat ctgtgaccta aatcaaatat atctgagata aagctaggta
     4561 ctttttctgg aactcctgga gttatagcta tttttatatt tttatagtta ttatcattca
     4621 tatatggaat tggtctaata ttagtcactc caattttata aaataaactt atagtttcta
     4681 gagtagtttc atcagaatca tttacgatta gagcatttgt accctgtggt aaagatagta
     4741 gattataaat tttatcttcc ctaaaagttc ttcttaccac aatcactttt ttcttatcta
     4801 gtatattatt tataattttg tctaatcttt ctactgacat tactaatatc acatcatcat
     4861 ttataatatc attatcattt atttcattta tgaagtatct attaatattt atagaatctc
     4921 caaaaactaa tttcaaatta ttttctaaaa agtctattaa atcttttcta ctatcattta
     4981 ccagagctac tgattttttc atttatttct ccttatataa taaatagttt ccaacaaaat
     5041 agttgtataa agcaatgtaa ttttgataat ttaaatttat caaataaaaa agaaagtgtc
     5101 tataatgact ttataaaagt tgcattaaga cactttcttt cttataatta aaaatcttgt
     5161 caccaaatcc ccctaattgt tgcttaaaac ttaaactgta tgtatatttt tcatttctat
     5221 tcgattaaat tataatatac acccaaaaaa atttatttta ataaattcta ttgataatat
     5281 aattttgtaa atatagaatt atattaaaat aaattatata tgaaaatata tatgtataag
     5341 tttattctgc gtgagtagaa tgaatttgtc aagtttaatt tagttgtaat tgtatctttt
     5401 attaaaaata atataaatta aaacatataa ataaaatatt ttatacaata tattgtaaag
     5461 gaggtaactt tgatgaaagc agaaaaaaca agtatatatc caattattaa aaataattta
     5521 aacaaaatat caattgttga atataaaaag ggtcaaagat ttgtagcatc agataaagac
     5581 ttacaagaag tgttctttat aatagaggga gttgcattag tggagtgtac tactagagga
     5641 ggaaataaat ttcttgttga cattgtacct gaaaatgaat ttataggcaa aatcagttac
     5701 atatatgaac ataatttgaa atgtgatata tttgcaaaga ccaatataaa attatttcga
     5761 tttgaaaaaa atgtatttga agagttttat ctcaaaccag attttattgc actatttcac
     5821 agaaaatgta caagaagaat atatgaatta tataaaacca gaatggtaag agaactattt
     5881 tcttgcacag aagttattgc ctattgtata tcaaataaac aagaaaataa tgtctgcaat
     5941 ataaaagcta ttcgtaattt cagtgaaatc tattcaatta gtagaaaaag tagataccat
     6001 tctctgctaa agttaactga aaaggagata gtaaaaaaaa tgggtaatac atatgaaatt
     6061 ttaaactatg atgaattaca taaattggca tttgaagtaa aagagttttt ggaagatgag
     6121 taaaaattgt tacttaatca aaataaagta taataatttc tgtaaaaaat agaaatagtc
     6181 tcactgaaaa tcaaaaatac tttagttatt ttcaatgaga ctgtttagaa atattgtata
     6241 cttataatgt atagtataat tattaatcaa tttcctttac tatattaata gcccattttt
     6301 tagataatgc tctaggaaca ccaaatataa acttaaccac ttcttcacta taagtgagta
     6361 aaacgagtac aaatataggt gcacctttaa atgcagctat aaaagttaga ggaatagaag
     6421 ctaaccacat acatcctaat tctagaaata gagcatattt agtatctcct ccacttctta
     6481 aaataccaat tataaccaat gtattaaaag atttaagagc cattagtatt cccatgataa
     6541 agaatatctt agttatatca gaagctaagc tatcagaaac actaaacatt tttaataata
     6601 atggtatatt taaaattaaa ataattccaa gtattaaacc agctgaaaat acaagtatag
     6661 aaaacttttt agcatattca atggctcttt taatatggtc agctccaagt tcatttccaa
     6721 gcataataga tgcaccagat gcaatacata cagctgtcat tatgaagaaa ttacctgtac
     6781 tggttgctat ctggctagct gctatagcag aagtaccagc tcttgcatat gcaacagaat
     6841 acaggacagt tccaattgcc catacagagt catttacaaa tataggaaag ctttttgatg
     6901 aaaaagattt tataaaaatt ttatcaatag cttttagatt ttttagacca aactttaata
     6961 tatagtcttt tttataaagg taaacataag taatcattaa aattaattca catattctag
     7021 caataacagt agctagagca gcacctttta cacccaatgc gggaagaccg aagttaccaa
     7081 atataaatcc ataatttaaa ataacatttg ttacaagtgc aaatgcacta caaatcatac
     7141 ctaacttagg atttctaaca cctcttgaac cagtactaaa tacagtactt acagcaatta
     7201 atggataact aaatactgca atactaaagt aatctataca aagttttacc acctcagaat
     7261 catacgaaaa tatgtgtata attggctttg gtgttagtaa agcaggaata acaaatacaa
     7321 aacttaaaac aattgccaat acacaagtaa gacctgtgac ttttcttata ttactcacat
     7381 ccttctttcc ataaaactgt gaaataaaaa ctccagcacc tcctgtgata ccagataagg
     7441 acatattaaa aagaaagaaa aattggtttg caactccaac tgaagctaca gatgtctccc
     7501 ccaaactact tatcataatt gtatctatta catttacaga agtagaaatt aagttctgta
     7561 tgataatagg tatacataaa gatagaagta ttttataaaa tcttttattt tcgtctttta
     7621 aagaaaatag ttcttgcaaa taatcctctc ctttttacat aaattcttcc cactcatcat
     7681 atagagaggc aaggttattt tctaaattaa ttttttcttg gctaacttct ttagctttat
     7741 ctggattaga gtatacttct tcttgacata aaagtatatc taatttttca atttcaatct
     7801 ctaacttttc aatttctttt tctatatttt gtctttttat tctatttttc ttttctattt
     7861 ctctttgttc tctctctttt cttttttcat cttttatttg agttctagtt ttttcttctt
     7921 tttcttctat aatactcatc tcttggattt gccttttttt atctatataa taatcataat
     7981 ttcccagata ttcagtaatt ccattttcat ctaaaactaa aattttatca acaacagtat
     8041 ttagaaagta tctatcatgt gatattgtaa atatagtccc atcataatta gttaatgcct
     8101 cttcaaggac ttccttagaa tcaatatcta ggtgattagt aggctcatct aataacaata
     8161 agtttgcatt tgatagtata agtttaagta tggcaactct agctctttct ccaccactca
     8221 atgtagaaat cttcttaaaa acttcttcat ctacaaataa aaatgcccct aacatatttc
     8281 tcaaagtagt ttgagtaaga tgagtattat tttcccaaat ctcatcaatt attgtgttat
     8341 ctaaattaag agttttttgt tcctgatgga agtaggaaac atgtacatta gttccaaatt
     8401 taatattgcc actaagaggt tgtagttcat tagttattat tttaaataat gtagatttgc
     8461 caacaccatt tgcacctata agtgcaactt tttcccctct atatatatct aaatccaagt
     8521 ctttaaaaag tattctttct ccataaccca tagatacatc tctaatttga agaacatcat
     8581 taccactctg gacagaaggc gtaaattgta tacgagcttt tttcctataa gcttctggtt
     8641 tatctaaaac gtctaccttg tctaatgctt tttctttact tcttgcacgc tttaggtgtt
     8701 tttctctacc ataagctttt agtctttcaa ttgattcttc ttgctttttt atttcttttt
     8761 gttggtcttc aaatttctta agctctagtt ctttttctat tttagataac tcaacaaatt
     8821 tagagtagtt accattatat actttaagtt ttttgttgtg aacttcaaaa attctattta
     8881 cggattggtc taagaaatat ctatcatgag atattaacat gacagttcct ttatattgtt
     8941 ttaaaaatac ttctaaccat tctattgctt cagagtctaa gtggttagta ggttcatcaa
     9001 gtaacaatag agttggtttc ttaagaagta attttcctaa aagaactcta gttttttcac
     9061 caccagaaag tatgcttatt ggcttatcca tatcattgtc actaaatcct aatcctttta
     9121 gaactccttt ggcttcagat ttatatccat atccatttaa atctgaaaat aattctagtt
     9181 tatgtgaata ttcatccatg attttttcta taattggaga gtttgttttt gtactttctt
     9241 cagatatttt aacctccaat tctcttaaat aggattccat ttctatcaaa tttttaaaaa
     9301 cttctagcac ttcttccaaa atagtattat ccgaataaaa attggtattt tgttctaaat
     9361 atccgatttc acaatcttta gaagtataaa tatctccact atcatatcca taaattcctg
     9421 aaattatttt aaataaagta gtttttccag taccattaac accgattata ccaattttat
     9481 cgccttcatt tactgtaaaa ctaatatttt ctaatataga atctatacca aaacttttat
     9541 ttaagttatt acatgacaaa acaatcataa atttctacct ccttgaacta tctaaaatta
     9601 taatgttttg atataatata atcaaggtta tatgtattag ttttgaaaaa gaaatatttt
     9661 attgtgaatc aaacaaaaaa gaggacactt ttaggaggtg aagatgttgg gaaataaaaa
     9721 tatatcaatg gcagttataa gaaggctccc aaaatatcat agatatcttg gagacttatt
     9781 agatagggat atacaaagaa tatcttctaa agaattgagt gatataatag ggtttaccgc
     9841 ttctcaaata agacaagatt taaacaactt tggtggattt ggacaacaag gatatggtta
     9901 taatgtagaa gctcttcata ctgagatagg taaaattctt gggttggatc gaccatacaa
     9961 cgcagttctt gtaggagcag gtaacttagg acaagctata gccaattatg caggatttag
    10021 aaaagctgga ttcgagataa aagctttatt tgatgcaaat cctagaatga taggtttaaa
    10081 gataagagag tttgaagtat tagattcaga tactttagaa gactttataa aaaacaataa
    10141 tatagatatt gctgtattat gtatacctaa aaatggagca caagaagtta ttaatagagt
    10201 tgtaaaagct ggaatcaaag gtgtatggaa ttttgcacct ttagatttag aagttccgaa
    10261 aggtgttata gttgaaaatg taaacttaac agaaagttta tttaccttat cgtatttaat
    10321 gaaagaagga aagtagacaa cttaaacata ttaataatga gcagttgtga agagtattga
    10381 gaaagtcaga agatttaata ttaaatcctc tggctttttg aaatattagg ataaaaattt
    10441 aaataatgta tggaaataaa caatattaag gagagtggtt tttgtggagg aattatggaa
    10501 aaaggcaatt gaatttcatg gtcatgaatg tccagggtta gctataggat ttaaagcagc
    10561 acttgcagca agaaaatatt taggatgtaa acagtcagga gatgaggaaa ttgtatgtat
    10621 ttctgaaaat gatgcttgtg gaatagatgg tatacaagtc gtgctaagtt gcacaatggg
    10681 taaaggaaat ttactactta ggatgactgg gaaatcagta tatcatttct ttaataggga
    10741 aaatggaaaa tctataagaa tatatgtaaa gtcaaagcca tttcaaatgg atagagaagg
    10801 atacaaaaag tacttattag aaagtgattt tgaagaaata tttgagatta cagatactaa
    10861 gttaagactt cctgaaaaag caagaatatt taaatctctt aaatgtgaag tgtgtggtga
    10921 atttgcatct gagcaatata taaggattga agaaggaaag aaagtatgtc ttgattgctt
    10981 taataaatat gaaagatttt atgaggagta ttaaaattat aaattagatt aaagttaaaa
    11041 gtattagata tgtactaaca gtattttaag atgaattagg tagcaacata ataaaatata
    11101 taaataatat tacttgaacc atacataatt aaaaagaggc tgattagtat ttagaaaata
    11161 aaatcagtct ctttatgaat aacgaattat tattctggtt gaggtgcatc tacaggacaa
    11221 gctcctgcac aagaaccaca gtctatacaa gaaccagcat ctataacata tgcgtcgtct
    11281 ccagctgata tacagctaac agggcattca gcctcacaag caccacagct tatacaagcg
    11341 tcagtaattt tatatgccat tttgaaatcc tcccttttat atgtattgta attcaataac
    11401 attataacaa atattattga atataacaat taaattaatt ctacaacaaa aactttatta
    11461 tgatattctt gttttaaagt tttacaataa agtttaatct gcttatattt ttatttattt
    11521 taaagaagtt tattttaaaa ataaaattaa atttaaaaag ttatgtattg attatattta
    11581 aaaatgttat actctaaaaa agtatatttt attttaaaat ttattaatac aaaggagatt
    11641 tactatgaaa aataaattag tttacatatg tattatgagt ctattgctat ttgtagtagg
    11701 atgttctaat aatccaaata aggaaagtac cattaaaaaa gactctaaga ataaccaaag
    11761 ccaagttaaa gaagaaaaaa gagaacctgt gaaaaaagat ataactataa gtttcgctgg
    11821 tgatgtaact atggggaact ataaaggttc atcatattat ggcagttttg accatgaatt
    11881 taaaagacaa ggagaagatt acaattattt tcttaaaaat gtaaaacctg tatttgaaaa
    11941 agatgactta acagtggtta atttagaagg tccacttact acagcgtcaa atgcaaaaga
    12001 aaaaaaattt gcatttaaag gaaagcctgg atatgtaaat attttaaaat ctggaagtat
    12061 agaggcagta agtattgcaa ataatcattc agaagattat tttgaagaag gaatgaaaga
    12121 tacacagttt atattggatg agaataaaat aaattatttt ggattaggga aagatgctgt
    12181 tgtagatgtc aaaggaatta aagtgggtct attagggtat aatggattat caactgaata
    12241 taatgaaaaa aatttaaaac aaatggaaga tgatattaag tccttaaaaa agaaatcgga
    12301 tgttgttgta gtgtactttc attgggggat agaattagat tattatccag ataaaaaaca
    12361 aaaagatttt gctcattatg ctatagacaa gggagcagat ttagttatgg ggtctcaccc
    12421 acatgttatt caaggaatag aaaagtataa aaataagtat atagcttata gtctagggaa
    12481 tttttgcttt ggaggaaata agaatccttc tgatacagat agttatatat atcaacaaac
    12541 ctttactttt tcagataata aattaacttc aattaaagag ccaaatataa taccaacctc
    12601 aataacatct agtagctcca gaaataatta tcaaccaaaa gtattggatg gaagtgagaa
    12661 ggatagagtt ttaaataaac ttgaaaaaat aagcaaagat ttaaataaat aaaatgtaaa
    12721 aaaaaataaa tatatatatt tattttaata atttatattt tgtttagggt atggtaaatc
    12781 gtggtattaa ataagtagat tttaatagtt aaattatagt caattataat aaagctattt
    12841 aatctacttt tttaatataa aaatataagg gggaatttgt aatggcttgt aacacttgta
    12901 aaatgtgcga aagtgcagac aagaaattag aaagttttgt agcttcaaag gatgttgaaa
    12961 cagcatttca tagaacagaa gatcagaaag ttaagtgtgg ttttggactt cagggggttt
    13021 gttgtagact ctgttcaaat ggaccatgta gagtaactcc taaatcacca agaggtatat
    13081 gtggagcaga tgcagacact atagtagcaa gaaacttttt aagagcagta gcatcaggag
    13141 cagcttgtta tttacatgtg gtagaaaata cagctaagaa tttaaaaaat gttggaataa
    13201 ctaaaggtgt tgttaaagga gaaaaaacat taaatcaatt agcagagatg tttggaatag
    13261 aaagtgatga aaagtatgat aaatgtataa aggttgcaga caaagttatc aacgatttgt
    13321 ataaatcaag agatgataaa atggaattag tagaaaaaat agcttatgca cctagagtga
    13381 aaaagtggaa agagttaggt ataatgcctg gtggtgcaaa gtcagaagtt tttgatgcaa
    13441 tagtaaaatc atcaacaaat ttaaatagtg atccagtaga catgctagtt aattgtttga
    13501 acttaggtat atcaacagga ttatatggtc ttacactaac taatctttta aatgatgtta
    13561 tgttgggaga accagttata agaatggctc ctgtaggatt taatgtaata gacccagact
    13621 acataaatat aatgataaca ggccatcaac attcaacatt tgcaaatttc caagatagat
    13681 taaaagatga agatgttata aaattagctc aatctgttgg tgcaaaaggc tttaagctag
    13741 taggatgtac atgtgttggt caagatttac aattaagagg agaacattat caagaagtat
    13801 ttgctggaca tgcaggtaac aattttacaa gtgaggctgt tttatcaact ggagcaatag
    13861 atatagttct ttcagaattt aactgtacta taccagggct tgaaccaata gcagataaat
    13921 ataaagtaaa aatggtttgt ttagatgatg ttgctaaaaa agcgaatgca gaatacatag
    13981 gtttagacag aagtaaatta gatgaactta gtaacacttt aatagaaaaa gcattggagt
    14041 cttataagga gagaagagga agtattgaga tagatatacc aaaagaccat ggatttgaac
    14101 aatctttaac tggtgtaagt gaaaagaacc tgaaagcgtt tttgggagat tcatggaaac
    14161 ctcttattaa tttaattgca gaaggaaaaa ttaaaggtgt tgcagctgtt gtaggatgtt
    14221 caaatatgac agcaggagga catgatgtaa atactgttga acttactaaa gaattgatta
    14281 aaaaagatat aatagtacta tctgcaggat gttctactgg aggattagaa aatgttggtc
    14341 ttatgtcacc tggagcagaa gaattagcag gagaaaactt aaaagaagta tgtaagactt
    14401 taggaatacc accagtatta aactttggac catgtctagc tataggaaga ctagaaatag
    14461 tagcaacaga attagcagct gaacttggaa ttgacctacc acaattacca ttagtgcttt
    14521 cagctccaca atggttggaa gaacaagcat tagctgatgg agcgtttggt cttgcccttg
    14581 gcttacctct tcatttagct ttacctccat ttataacagg aggaaaattg gtgacagaag
    14641 tattaacaga aaaattaaaa gacttaacag gaggacatgt tatagtgaat ccagacccta
    14701 aatcttcagc taatcaatta gaagaaataa taatagatag aagaaaaaat ttagggttaa
    14761 aggatgtgga atgcaatgca tagaattttt ataaataaag atttatgtac aggatgtaag
    14821 agctgtgtac tagcatgtat gctaaaacac aataaagatt atgacatgta cactcttgat
    14881 ttagaaaata tagataatga tagtagaggg catatagaat tagatagtaa acataataat
    14941 ccagttccaa ttctttgtag acactgtgat gaacctgaat gtgtattagc atgtatgagt
    15001 ggtgcaatgc ataaagatag tgaaagtgga atcgtttcat atgatgaaga gaaatgtggt
    15061 tcatgttata tgtgtgtaat gtcttgtcca tatggattat taaagccaga tgatagaagc
    15121 aagcaaaaca tacttaaatg tgatttatgt aaagatgagg agtatcctag atgtgtagct
    15181 aattgcccaa gtggagcaat tgaattacag aaggaggaaa atgatgaatt atgtagtgtt
    15241 aggggctagt gcagctggta taaatgcagt aaaaacatta agagaattag ataaagattc
    15301 aaatatagta gtaatttcta aagatgaaaa cgtatattca agatgtatgt tgcatcacgt
    15361 tatatctgaa cacagaactt taaaacaaat aaattttgtt gatgaagatt ttatggagca
    15421 aaataatgta aaatggattg caggtaagac tgttaaaggt atagacataa ataaaaaggt
    15481 agttcaaaca gaagacatta ctgtaaatta tgataaactt ttaatagcta caggtgcatc
    15541 ttctgctatt cctcctataa aaaatttaag agatggaaat tttgtatatt ctgtgagaaa
    15601 catagatgat atttataaaa taaaagaaaa agcacaaaat tctaaaaatg tagttataat
    15661 aggtgctggt ttagttggta tagatgcatt agtgggatta tttaaatatg agcagttaaa
    15721 tatttctgta gcttttatgg aaaagtacat tttagataga caattggatg aatatacagc
    15781 atcagtgtat gaaaataagt tcaaagaaaa aggtgtaaaa ttttacccaa gtgcatcaat
    15841 acaagaaatt gtattggata acagtaaaaa tgttacaggt gttgcatttt caaatggtga
    15901 agttttagat gcagacatgg taattgtagc tacaggggtt aaaccaaatg ctgacttttt
    15961 agatgggaca ggaatagaat atgatagagg tataataata gatgatatgt gccaaacaac
    16021 acaaaaagac atatatgcag caggagatgt tgtaggtaaa aatgctattt ggcctctggc
    16081 agtaaagcaa ggaattgtag ctgcctataa tatggttgga aaagataaga agatagaaga
    16141 tgaatttgct tttaaaaata gtatgaattt catggatata ccaactattt ctataggaat
    16201 gaatacacct gtagatgata gctataaagt attaaccaga catggaatta atgattataa
    16261 gaagtttgtt tttaaagata atgtaatcta cggagcagtt atacaaggag atatttcata
    16321 tgtaggtgta ttaacttatt taataaaaaa taaagttgaa atatatgatt tagaaaatag
    16381 gatatttgat gtatgttatg cagacttttt taatataaaa gaaaatggag aattttgtta
    16441 tagtgtatag tatatacgtg gagtaaggtt tataaataca gtaaatcaat aaatagagtt
    16501 attctaaaat aagaaaaatg acaaatctta tttagaaata gctctatttt ttgtaattaa
    16561 atttaaatta tattcaattt gtaaaatatt attttgaaca attatacata tactctctag
    16621 ttagaggtaa atcatttttt atacctttag tgaaaagtat ttgatgtata tctataatac
    16681 cagtgttgaa agcagcagca caagaacaaa ggtataaatc ccacattctt ataaacttat
    16741 catcaaacat ttctttaatc tttggaagat tctcagagaa acttttttgc cagtatagta
    16801 aggtttttac ataatgtaat cttaaacttt ctacgtctat agtatgatat ttgtaatcac
    16861 tacaaatatg tatcatttct cttaggctag gaataactcc tcctgggaaa atatattttt
    16921 ttatccaagg gtctccataa gattcctgca atccacttat atagtgaagt aaaaacaatc
    16981 caccatcttt taaaacagca tttacgtttt taatgaaaag ttcatagttt tctctaccaa
    17041 catgttcaag cattccaacg cttacaactc tatcaaacat aaggtctgat ttttttaatt
    17101 ctctatagtc cataagtctt acctcaagat agtcttgaag gttctcttct ttaattcttg
    17161 cgttaaattc cttaaattgc tcttcgctaa gtgtaattcc aacgccgtga attttatatt
    17221 tttttgcagc ttctattagt aaaaatcccc aaccacaacc aatatcgaga aggctcatac
    17281 cttcctctaa atttagttta gttaatatgt ggtgaacttt attgacttga gcatcataaa
    17341 gagtatcatt atcatttcta aagtatgcac aagaataact aagtgtctta tctaaccata
    17401 agctataaaa atcgttgcca atgtcatagt gggcatgtat ttctttcttc tgatgtctca
    17461 ttgaatttga tgagtgcaat agatgtttta cagctgaatt atcaatattg aatttgtcta
    17521 tttgttttaa aagtagattt aaagttaaga ataaatctcc ctcaacttca atgtctctat
    17581 ttatgtaggc ttctccaagt gctaaagatg tactttttaa tagttcagac ttgctaatat
    17641 cattatttac tataactttg aactgagggg agccctctcc aattagaaat tcttcctcat
    17701 ctttaagcct aactagaaat ggtgtttcac caaatttctc taaatagtct tttaaaaaat
    17761 tttttgtaat attcatatta ccagctcctt ctaatgtaaa tccagtaagt ttccctgctt
    17821 aaaatatatt atagtccttt ttttaaaaaa gtaaaatttt ttcaataaat tttttattta
    17881 aaggaaattt attttttata aagaaatttc atgttgtagt atattttttg cttataaatt
    17941 ttggtactgg atataatatt aaactgttaa tgatataata aatttaatct ataaagtaaa
    18001 taaaattttg taataaatag ttaaagctat tttataagga gatatatgat ggaagtatat
    18061 gctttggttg ggtcaagtgg cacagggaag agctttaagg ctttagagtt cgcatatgaa
    18121 aatgatatag aatatataat cgatgatggg attttaatat acaaaaacaa ggttttagct
    18181 gggatatcgg caaaacaagc aaatactact atagaagcag ttaaaagggc tattttttat
    18241 aatctggagc atagacaaga agttagagaa gcaattaaaa aagaaaatat aagaaaaatt
    18301 cttattattg ggacatcaaa aaaaatggtt aatcaaattg tagagagatt gtcaattgga
    18361 agggtctgta agtttataaa tatacaagat ataagtacta aatatgaaat agaaatagca
    18421 aaacaagcta gaaaagaagg aaatcatgta attcctgttc cagccgttga gataaaaagt
    18481 atggcaagtg gtctcagtat aaattctttg aagagacttt ttagaaaagg aaataatagg
    18541 aatatggtag ttttagaaaa aacaattata agaccaactt ttagttatat aggaaagttt
    18601 tatattagtg ctgatgtaat taaacagatt attgaatatg aagtatacaa ctttggaagc
    18661 attgatagaa taaataaaat caatatagag aattgcaata attttatgaa tatttttgta
    18721 agtataaata tcaatgattt agaaactata aaaaaaattg aagacataca acagacaata
    18781 aaaaagtcta ttgagaaaat gactttagtt aatgtacaaa aaatagatat taacattcat
    18841 aaaattaaaa aaataaactt cctccaatgt taaaaaataa actgagaaaa tgatatacta
    18901 atttgcaata aagtgtgcta taattaaact gtaaatttag gaaatggttt tttctaaatg
    18961 gagtatacat aattataacg tatttataag ggggctttca aatgtcagga aaagatgtaa
    19021 atgtcttcga gatggcgcaa tctcaagtaa aaaatgcatg tgataaatta ggtatggaac
    19081 cagcagttta tgaattatta aaagaaccta tgagagttat agaggtttca attccagtaa
    19141 aaatggatga tggttctata aaaactttta aaggatttag atcacaacat aatgatgcag
    19201 tagggccaac aaaaggtgga ataagattcc atcaaaatgt ttcaagagac gaagtaaaag
    19261 ctttatctat atggatgact ttcaagtgtt ctgtaacagg tataccatat ggtggaggta
    19321 aaggtggaat aatagtagat ccatcaactt tatctcaagg tgaattagaa agattaagta
    19381 gaggatacat agatggaata tataaattaa taggtgaaaa agttgacgtt cctgcaccag
    19441 acgtaaatac taatggtcaa ataatgtctt ggatggttga tgagtacaat aaattaactg
    19501 gacaaagttc tataggtgtt ataactggta agccagttga atttggtggt tctttaggaa
    19561 gaacagctgc tactggattt ggtgttgctg ttactgcaag agaagctgct gctaaattag
    19621 gaatagacat gaaaaaagct aaaatagctg ttcaaggtat aggaaacgtt ggttcttata
    19681 cagttcttaa ctgtgaaaaa cttggtggta ctgttgtagc tatggctgaa tggtgtaaat
    19741 cagaaggttc ttatgctata tacaatgaaa atggtttaga tggtcaagct atgttagatt
    19801 atatgaaaga acatggtaac ttattaaact tcccaggagc taagagaata tctttagaag
    19861 agttctgggc ttcagatgtt gatatagtaa taccagctgc attagaaaac tctataacta
    19921 aagaagttgc tgaatctata aaagctaaat tagtttgtga ggctgctaat ggaccaacta
    19981 ctccagaggc tgacgaagta tttgctgaaa gaggaatagt tcttactcca gatatattaa
    20041 ctaatgctgg tggagttaca gtttcttact tcgagtgggt acaaaactta tatggatact
    20101 actggtcaga agaagaagta gagcaaaaag aagaaatagc tatggttaaa gcatttgaat
    20161 ctatttggaa aatcaaagaa gagtacaatg ttacaatgag agaagctgct tacatgcatt
    20221 caattaagaa agttgctgaa gctatgaaat taagaggatg gtactaagat ttactcttaa
    20281 taaataatag gatataatta tttaagatat aaaggggctg tacatagtac agcccttaaa
    20341 ttatgtggct tacaatgaag taagctattt ttgttttaac ttataaataa cttgataaat
    20401 tatgtaattt agaatgcata aataagatgg gtgaaaatta atggttgatt taattttgaa
    20461 tgtatttttt accaccacat gattacaaat tagaggagtt agattggatt tttggacatg
    20521 aacttatgta ttttaaaagc aaagaccttc atttaaagta tctagtatta tttttaaaaa
    20581 tagtatattg gtttaatcca tttatatata taatggaaaa atatatggat ttggattgtg
    20641 aactttattg tgatgagaga gttttaaaaa attgtactgt acaacaaaag caagaatatg
    20701 ctctaactat tgtaaattca atgaaaagag gtataaattt ttcaaataaa tttgtaactg
    20761 gattaaataa acaatctgat attagaaaaa gagtaatgaa catgttcagt gaaaaacata
    20821 aaaatggtat cttaatggct ttgattataa gcttgttttc ttctattaca ttttttaaat
    20881 tcgattcaac tagtcttatt gaagagaatg atttcttaga gaggtcaaga tatgcgtttg
    20941 aaggaaggca agaagacatg tttgtaacaa tagattctac atatgcagat gcacctataa
    21001 aacttagaaa agagcatgaa gaaaactgta gagtcaatgg aatagtacca aaagattcag
    21061 attcaataga aattattcct agattttata aagattgtat ggatttaaaa aaataagtta
    21121 gacttaatat tgatgttgat attatgaatt ttttatattt aagcaattga aaattttatt
    21181 atagattcaa ttttatatgt gtttaagtat gaaatttata gatagttgaa ataattaaat
    21241 atgattgatg cataggaatc attactaagc tataattaat tataggggag tttaaataaa
    21301 ttatgagtta cacaattata aaatgataaa aaatagttat ctgttacaaa aaatgtatct
    21361 ttttaattaa taaagataat atgaaaactt aaaaggcaaa taaacttaaa cataaaatac
    21421 tcttaaataa gataggagaa aaatgtatgt ctaactttat tctaaatggg atttttagaa
    21481 cagttatagt aagtagtcta agcattcttc tgatattgat tttcaagaaa aatgtattta
    21541 aaagatttag caaaaaattt aattattata tatggatgat agttgttatt aaattatttt
    21601 taccatttac atattatact tttacaataa atatcttgag aagtaaaaaa cacattaata
    21661 ttaataacat aaatttagag ggatttaata atgtttcaac tataagtaat aatattatat
    21721 tgtacacttg gattataact gtagtagtgt atttaattta cactatattt aaatatataa
    21781 aacttaaaaa tttaataaat gacttatctt atgatgttga tgatagagag attgtaaatc
    21841 tttataaaaa tatattagaa gaatttaata taacaaaaga tataaaactc aaatactctt
    21901 atgaagttga aacaccagca ttttttaatt catgtgtact tttgccacca catgagtata
    21961 aattgaaaga gttagactgg atttttagac atgagcttat gcattttaag agtagggacc
    22021 tttatttaaa atatgtaatc ctgtttttaa aaacagtata ttggtttaat ccatttatat
    22081 atataatgga taaacatata gatttagatt gtgaacttta ttgtgatgaa agagttttaa
    22141 aaaatcgaaa ttcagaggaa aaaaaggatt atgctttaac aattctaaat gcaatgagaa
    22201 aaggttcaaa tacttcaaat aaatttatag ctggactcca taagcaatct gatattaaaa
    22261 agagagttat gaatatgttt aatgaaaagt acaagaatgg tatattaatg gcattaactt
    22321 tatgtttatt atcttctatt acttttttga aggttaattc aacgagtatt gttaatctta
    22381 atgtattacc taaaggattt gaagacttac gaactgttag cagtatacgt ttttcagtta
    22441 taggatttac atatgcagat gctcctaaaa atatgaggga agaatataaa ataaattgtg
    22501 aatcattagg tttgatacct aaagactctg ataaaataga agttggtgta gaatattatg
    22561 acagtctatt gaatgattaa ataaatatta ttttaacaga tattaattat aaagttttga
    22621 atagtaattt gttgagaaat aaatatatcc ttataaaaat agatacttat ataccaagaa
    22681 taaaaaatag ttaagatagt acacaaggat atacttataa agaacttaaa taagtgaaat
    22741 aaattattaa ttataaggtt tataatttta aaaaattaga taaattcagg tgtaaaatac
    22801 tataaaacac aattcggaaa agtgtatgtt gaacttcatt taaaatagaa ttttcaaagt
    22861 tgttatagta agtagtttaa gcattcttct tatattaatc tttgagaata atgtacttaa
    22921 aaaagttagt aaaaaattta actattgtat attaatgata gttgctattg atatattatc
    22981 taaaaaaatt aagtatgaaa agattactgc taggacaatc ttttcatact taatttttta
    23041 atatttatat tctccaaaat tttcatcttt ttaacttaga attattagaa tttgagaatc
    23101 actattagga aataggtttt gatttatgca gggttaaaaa tttcacagaa tatctaactt
    23161 tatactaaat ccatcaaaaa atatacgcca tataaaagcg cataaaaaaa cacataaaac
    23221 aatatttatg cgcactttaa cctcgaatgg tacaaaattc tttactttta cagacccata
    23281 ttatataatt aagtaaataa tgtatattta ggtgacatat tggataagct aatttattta
    23341 ttttattaat ataatgatac tataaaagtt atataaagtg gtttacaaaa aagttacaga
    23401 tagagctttt attaatgtat tgtgtattag tattttatcc ttaggtacac ttcacctaca
    23461 aaatagaatc ataagataat tatgggaaaa ttttaggagg tttatcgtga agaaaaagat
    23521 attaatacca gtatttgcat cagttatggc attatcagta agttcaattg taaatgcaga
    23581 tgaagtaaat gattcatctc aaaataagga tgataaaaca aatactgaat taaatttagg
    23641 tgaatataaa gaagtaaaat ataaagttgc aaaaataaaa gatggagtag ctataaagat
    23701 aagagaagaa ggtcaagttc aaaacatagc ttattctgga gatgaattta cggttttagg
    23761 aactcaagga gaatgggtta aggttaaagt tgaagatggc gaaggttggt tagctactag
    23821 atatgtagat atatctgaag gtgtaggata tactaacgct gataaagtaa acttaagaaa
    23881 agataagagt gaaagttcag aagtaattga agagctggaa aaaggaagtt ctttattggt
    23941 tttggaggat aatggagatt ggttaaaagt taaagatggg gaaacagaag gatatgtaaa
    24001 atcatcttat atatctgata aagctcctgt aatagaagag ccacaagtaa acccaagtat
    24061 tgaccaaaat gtagattcta caaataataa tcaacaaaac aatgcaaata ctaatcaaca
    24121 aaataataat tcaaatgtgc caacagctaa ctctaatgca gttcaagctg tacttaactt
    24181 ggcatattct aagcaaggtt gtccatatgt ttggggagca gaaggaccaa acacttttga
    24241 ctgttctgga tttacacaat atgtgtatag aaatgcagta ggaaagaata taccaagaac
    24301 atctaaagca caatctaaat atggacaaac tgtaagtaaa gcaaatttac aaccaggaga
    24361 cttagtattc ttcacaacta atggttctgg ttctgttagt catgttggaa tatatgtagg
    24421 tgggggtaat atgatacatt caccatcaac aggaaaaaca gttagtgtaa ctagtataaa
    24481 ttcatcatac tatacagcaa gatttgttac agcaaaaaga atattataat cggtttgtaa
    24541 tatgacaaat tgataaatac ataaatatat ataaacgctc tatattatat ttaatttaat
    24601 catggaaaca aaaaatgatt atattttaaa tgtactatag agcgtttttg tatcacttta
    24661 aatctaatca agattcaagt taatatgact attaaatagg agccttttca tatgatgatt
    24721 atttgcgcaa tcccttgaca ggatagggta aaggtggtaa gctactaaca gtacaaaaat
    24781 acttttaatt ttagttcaga gaggctaaaa aaggaggacg aaagatgtta aaatcaagaa
    24841 atttaatcca accagaagac ttttcaatag aagaaataga tgaaatatta gaattagctc
    24901 aaaaaataat tgacaatccg tcaaaatatt ctcgtatatg tgaaggaaaa ctattagcta
    24961 cattatttta tgaaccatca acaagaacaa gattaagctt tgaatctgct atgaacagat
    25021 taggaggacg tgtagtaggc ttttcagagc caaattcatc ctctgcatca aaaggtgaaa
    25081 ctctaggaga tacaatgagg atagtatctg gttatgttga tataatagct atgagacatc
    25141 ctcaatcagg tgcagcttca gaagcagcta gatatacgga agtgccattt ataaatgcag
    25201 gagacggcaa aaaccagcat ccaactcaaa cacttacaga cttacttact ataaaatcat
    25261 taaaaggaac tttagaaagc catacaatag gattatgtgg tgatttaaaa tatggaagaa
    25321 ctgtgcattc tttggttaag gctatggcaa gatataaaaa tacaaagttt gtatttatag
    25381 cgcctgaaga gttaaaaatg ccagattata taaaagaagc tataaaggga catgcatatt
    25441 atgaaactaa taatttggat gatgttatag gaagcttgga tgttttatat atgactagag
    25501 ttcaacaaga aaggtttgaa gataaatcag agtatgaaag acttaaaaac tattatattt
    25561 taaataaagc taaattagaa aaggcatcta aagatatgtt agtaatgcat ccattaccaa
    25621 gagtaaatga aatagacata gatgtagata gtgatgatag agctgtatat tttaaacaag
    25681 ctaaatatgg aatgtatgtt agaatggctt taataataaa acttttaggt ataaatgaag
    25741 actaatagtt atcatataat agtaaaacaa aggagatttt gggatgtata aaattctgga
    25801 aaatatatat ataggcgaag atatgtatag aatgaaagta aaaggtaatt ttgaaggtaa
    25861 aatgggacaa ttctatatgt taagagcatg ggatacttat ccagtacttt caagacctat
    25921 aagtatacat gatatagatg aagaagggat aacttttctt tataaagtag taggagaagg
    25981 aactcaaatt ttgagtaacc taaaggtaaa tgataatata aaattagaag gcccttatgg
    26041 taatggatat gctaaggttg atggaaaggt agctctagta ggaggaggaa tcggtgtagc
    26101 tccactatat ttggttgcta aaaatataaa aaattgtgat gcatatcttg ggtttagaga
    26161 agatgttata ttagaagatg aatataagca agtatgtaat aaagtctata caacagtagg
    26221 aaatactttt gtaacagata taattgatgt tgagaaatat gattatatat taacatgtgg
    26281 tccaactcca atgatggaaa aattagttaa gatggtagaa ggtactaaaa cgagaattat
    26341 ggtatctctt gaaaaccata tggcttgtgg agtaggtgcc tgtttagtat gtacgtgtaa
    26401 aactaatgga ggaaacaaaa agacttgtaa agatggtcca gtgttctggg gagaggacgt
    26461 gatttttaat gggtaattta agtgtgaaat ttggaagtgt agaatttaaa aatccagtaa
    26521 taatggcgtc tggaactttt ggatttggaa aagaatataa tgagatttat gatatacaaa
    26581 aacttggtgg tataagtagc aagggtctta ctttaaataa aaaacctggt aacaatggta
    26641 tgagagttca tgagacacca tccggtatga tgaatagtgt tgggcttgaa aaccctggag
    26701 ttcaaggatt tatagactat gaattacctt tttttagtaa actagactta gtcagaatag
    26761 ctaatgttgg aggtgggaca ttagaagact acttattagg ggttcaaatg ttaaatgaca
    26821 agcctataga cattattgaa ttaaatatat cttgcccaaa tgtcaaagct ggtggaatgg
    26881 cttttggtat aaaaaatgaa gtggcaagag aagttgttcg tgaggtaaga aacataacga
    26941 aactgccttt agtaataaaa ttatcaccca atgcagaaga tattgtagga atggcaaaag
    27001 tttgtgaaga agaaggtgct gatggagttt cattagttaa tacttttaaa gcaatggcaa
    27061 ttgatataaa aaatagaaga ccagtatttg aaaatgtata tgctggatta tctggaccag
    27121 ctataaaacc tatagctttg agaatggtac atgaagtgtg taaaaatgta aatatacctg
    27181 taatgggaat gggcggaata actaaagcca cagatgctat agagtttata atggcaggag
    27241 ctacttgtat ccaagttgga actgcaaatt ttatgaatcc tagaataggt attgaaataa
    27301 tagatgggat taatgaattt atggatagag aaggaataaa aagtttagac gaaataagag
    27361 gaattatata aggtagaata aatagtattt taaagataaa aaatatagat taaataaaca
    27421 ataattttat aacattaaca tggaggaaaa ataatatgag taaagtagat gtagtggata
    27481 tattaaagaa aagtgatgca ttgttggagg gacatttttt attatcttca ggaaaacaca
    27541 gtaatagata cgtacaatgt gcaaaagtat taagatttcc agaatatgct gctgaggtat
    27601 taagtacagt tgttgaacaa ataaaagact tagatataga cttagtagta ggaccagcta
    27661 tgggtggagt aatagtttct tatgagttag gaagacaatt aggaaaagaa gctgtattta
    27721 ctgagagaaa agacaataca atggagttaa gaagaggatt tgaagttaaa aaaggagcaa
    27781 agataataat tgctgaagac gttgtaacta ctggtaaatc aactatggag acaaaaagag
    27841 tattagaagc cttaggtgga gaagttgtag gtgttgcatg tatagcagat agaactaatc
    27901 atgatatagg tatgcctata tatagtgcta taaaacttga tattcaagtt tatgaatctg
    27961 atgagtgtcc tttatgtaag gaaggaaaat taccagttgt taagcctgga agtagagagt
    28021 tcaaggaatt agggatgtaa taaaaactta attatttata gtgttactta aaaaatgtaa
    28081 attttttaga gtaaaaattt gtaatataac atataactta aaaataaaaa gcagttagcc
    28141 ttataaatga aggttagctg ttttttttgt taaaaatata tttacaaaat aagagatagt
    28201 agcagtacaa tataagtata aggtaaaagt attatatatt agggaggggt aagtatgaaa
    28261 aatcaattaa atgaaaatca taaaaaggtt gtattttttg gagtaggtgc tgtaggagct
    28321 acttttgcag aacaattttt taactctaaa tatgatttta aaattctttg tgataatgaa
    28381 agaaagaaaa gatatttaga agaaggattt ataataaatg gaaaaaggta tgattttaat
    28441 tatgtaacta aagatgagta taaacaagag gctgatttta taattatagg tctaaaatat
    28501 aataatttaa aagaaaatat aaaagaatta gatggattag ttggaaaaaa tacagttata
    28561 atgtctctgc taaatggagt tgatagcgaa gagataatag gagaaagatt tggaattgga
    28621 aaaatggtat attcatatgt taccaatata gatgcaaaga aaatcaataa taatattata
    28681 cacactacta atgggataat tgtatttggt aacaaagata atagtgaaga tagaaaaact
    28741 aatataataa ctgaagtctt tgatgatgta aatatagaat atattttatc aaaagatatt
    28801 caacgagata tgtggtggaa gtacatggtt aatattggtg taaatcaaac ttcagctata
    28861 cttggtgcac cttatggagt ttttcagagt tctgagcatt taagagaatt agcaaaatct
    28921 gcaatgaggg aagttgttgc tatagcacaa gcaaaagaca tatctcttac agaagatgat
    28981 gttgaaaatt cattacatag aatactagaa cattcaaaag aaggaagaac atcaatgctt
    29041 caagacgtgg aagctcatag acctacagaa gtagatatgt tttctaagaa tatctgcaaa
    29101 cttggaaaaa aatatagcat acctactcct ataaatcaga ctttatttta tatgataaaa
    29161 gtaattgaaa gtagatttta aagggtattt gtaagaaata ttgataatta ttgattttaa
    29221 attttattaa tgttatatac tatttaagtt actaaatatt tttaactctt caatgaaaat
    29281 agttgctgct tttgacaaag ttatatcttt tggaaatata tatgagaaat gtctgttgta
    29341 gctgcttcca agctctatga cagacagctc attgtttaaa acaggtaagc ttgtcactag
    29401 attagaaact attgtaattc ctaaattatt tctaacagat tctttgacag cataattact
    29461 tccaaaaacc atcatacttt ttggaataat ttctttaaca cttaaaaaca tatctaaata
    29521 gtctctggtt ccagaaccat cctccctgac tatccatttt tggtcttgaa gtttatcaaa
    29581 actaaaatct tttaataaat gactattgta tggaagtgct aaaaccatct tatcttcaaa
    29641 aaaatattct tgaataaatg aaggggaaga gcaagtgcct tcaataagac caatgtctaa
    29701 aatataatcc ttaacatgag aagatacgat tgatgtattt tttataaaaa cttctacata
    29761 tatgtcagga tacttttgag aaaataatgc taaaaaattt ggtagaatat attctccaat
    29821 agttaaactt gcaccaatct ttaagtgacc agttatagca tctgaaactt ggcttacatc
    29881 atgataagta atatttaaaa gatttaatat ttctttagct cttttgtaca atatttgtcc
    29941 actttctgtt ataaaaatgg ttttttgttt aatagacctg tttataagca caactttaaa
    30001 ataattctct agatttttta tgtgtttact tacacttggt tgtgatagat ttaagtattc
    30061 cccagcttta gtaaagtttt tgtattcaac aacagctaca aatgttttta attcttcaaa
    30121 caattttttg tctccttcac ctaatgaaat tttacatttt ttatatactt tctacagata
    30181 attatactat atataataac cattaaaaac attaatcatt acgatattat atatttattt
    30241 tacttatggt tattacaatt atatactatt gctatgaaga aaactatatt aattataagg
    30301 taggtatatt atgttaaaga aaaaaagcag tttgacatta aaaactataa gggaaatatt
    30361 accaggactg tttatatcag tgttagtagg ttatattagt atatttattt ctattttaat
    30421 tcctaaggta ggggcagcat caatttctat atttttaggt atgtttgtag gaaacctatt
    30481 tttaaatcaa aaggtatttc aaaaaggtta taaattttca gagacagatt tgttatcata
    30541 ttcaatagta ctattagggg caacactcag tgtatctacc ttaatagact taaaagtttc
    30601 aggaatttta tttataatat tgcaaatgac aataacaata atagctgcac tttatatagg
    30661 taaaaaacta ggatttgaag aaaactttag atttctaatg gcaagtggaa atgcagtatg
    30721 tggttcttct gccataggag caatagttcc agtggttaat gcgacagata aagaaaaggg
    30781 aattgcagta actattgtaa atgttactgg tatattcctt atgtttttac ttccaataat
    30841 atctcaattt ttatatagcc atgaacttgt aaaaacttca gcaatgatag gtggaacttt
    30901 gcaatcaatt ggtcaggttg tagcaagtgg agcaattgtt ggagaaaatg taaaagattt
    30961 ggctactatt tttaagatag taagagtaat atttctagtt gttgttgtat tagtatttgg
    31021 acatatgaaa aatcagtcta atagggaaat ccttgaagaa gaaaaggatg agataaaaaa
    31081 gaaaaaagta actataccat ggtatgtaat tggattcttt ataacttgtg cacttttttc
    31141 aatgaacatt ataccaaaag aagtatctgt gttgtgcaaa gaaataagta acaaactaga
    31201 aataatagct ttagcagcaa ttggattaaa agttaatgta aaagatttag tgaaacaagg
    31261 gaaagaagtt tctttatatg gtttatttgt aggtacagta caagttgtat cagctgtagt
    31321 tttaataaaa atatttatat agcacaaaaa tagtatttgt aatattaatt tgattaatta
    31381 aaataatatg atactaataa tttataatat aaataaaaaa tgaatttcga taagtttaag
    31441 tgggtataaa cttatagaaa ttcatttttt atttaaggta aaaatttaaa gtaaaatatt
    31501 attttacata ataataacct tataaatttt gaaattactt atctttgtgt taaaataagt
    31561 aaaatacaca tattaaagtt aagtttttag gcaaataaac aaaatgaaaa tataaatatt
    31621 aaggagattt ggtatatgaa tgtttatgaa aaaggtaatg gagttatact agaaggagta
    31681 acagattttg acccagtaca tatatttgag tgtggtcaat gttttagatg gcacaaacaa
    31741 gaagatggct catacactgg agttgcaagg gggagaatat taaatgtcaa aaaagagaat
    31801 gataaaatat atttaaataa tacgaattta aaggagttta acagcatttg gtataattac
    31861 tttgatttag gaactgatta tacagaaata aagaataagc taaaaaatat ggatgaatat
    31921 ttgaataagg ctactgaatt tggatgggga ataagaatat taagacaaga tggatgggaa
    31981 atgcttatat catttataat ttcctctaat aatagaattc ctatgataca aagagcgata
    32041 gaaaatttat caagaaagtt tggtaagtat ataggtgaat atgaaggtaa tgaatactat
    32101 gcattcccaa caccagaaga actaaataag gcctcacaag aggaaataag agcatgtcaa
    32161 acaggtttta gagataagta cataaaaagt actacacagg cagttataga gaataatgat
    32221 gaggtatctg aatatacaaa tttaagtaca gaggattgta gaaaagagct tttaaaattt
    32281 aatggagtag gaccaaaagt atgtgattgt attgcattat ttggtatgca aaaatatgat
    32341 tcttttccag ttgatgtttg ggttaagaga gttatgcaag aattttatat agatgaagac
    32401 atgagtttac ctaaaatgag aacttatgga atcgataaat ttaaagaaat gtctggattt
    32461 gctcaacagt acttatttta ctatgcaaga gaactcggta taggaaaata aattaagggg
    32521 gagaaattat gggagtaata ggaacaatat ttctgttcta tttaattata tcatatctag
    32581 ctggagccat aatttctgtg attatattgc ttgaaaatag agaccctgca aaaacaatgt
    32641 cttggctatt gatgtttatt atatttccag gtgtaggttt aatgatatat gctatttcag
    32701 gtagaaatat tagaaaaaga aaattattta agactcaaaa actagctaat aatataaaag
    32761 aaaagaaact atttgataca ttagaaaaga taacagaaat agttgaatta gaaaaagaat
    32821 ctataaaaca aaataagctt ttaagagatg aagaggatgg tagttataga aaaagggtaa
    32881 taaatatgtt gttaaagact ggtatgtttc cctttactaa aaataataaa gtggatgtat
    32941 ttgtagatgg aaatgaaaag tttaaaagac ttatagaaga tataagagaa gctaaagacc
    33001 atattcattt agagtacttt atcatcaaag atagtgaaat aggtagggtg ttaaaagaag
    33061 aacttataaa aaaggctaaa gaaggcatta agataagaat tttatatgat gatgtaggat
    33121 gctggagatt ttggtttaat agaaaatttt tccgagaaat gagggaagta ggtatagaaa
    33181 ttgcagcatt tttacctaca aaatttccta taataggagg gaaattaaac tatagaaatc
    33241 acagaaaaat tgttgttatt gatggaataa ttggatatac aggtggaata aatataggag
    33301 atgaatattt aggcaaaaat gataagtttg gatattggag agatactcat attaggatta
    33361 agggtatttc tgtatacatg cttcaaatga catttctgat tgattggtat tatacgacaa
    33421 aagaagtatt agtgactaaa aattatttcc caagtgtagg gaatgttggt gaaagtatga
    33481 tacaagttgt tgcgagtggt ccagacagtg actgggaaga tattcattat gcttattttt
    33541 ctgcaatatg tcaggctaga aaaaatgttt atatagaaac tccatatttt attccagatg
    33601 aaagtctact aaaagctata aagagtgctg ctcttagtgg agttgatgtg agaataatat
    33661 ttcctaaaat tgcagaccac aagatagtaa atatagcatc ttattcatat tttgaagaaa
    33721 tattaagagc aggtggtaaa gtttatttat ataataaagg atttatacat tctaaagtcg
    33781 taataataga tgataaaatt gcttctgcag gtacagctaa tatggattta agaagtttta
    33841 tgcttaactt tgaggtaaat gcatttatct atgatgaaga agttattagg gtaatgacag
    33901 atgatttctt tgaggattta agtcactgtg aagaacttaa tttggaggta tttaagaata
    33961 gaaatatcat acaaaaaatc aaagaatctg tagcaagatt attttcacca atattataaa
    34021 aaattattaa aaaaggtatt gaaaattatg tgtgattggt atattataat aattgttagc
    34081 actctattag atagagtgat aataaataaa aagtatatat ataaatctac atatataagt
    34141 agtattaatt taaaaataac taaaaacata ggcgaactag tctatactta atattttagg
    34201 aggcgtgaat aatgaaaata agaccattag ctgacagagt agtaattaaa aaagtagaag
    34261 cagaagaaaa aactgcaagt ggaatagttt taccaggagc agctaaagag caacctcaaa
    34321 tagctgaagt tgtagaagtt ggaccaggtg gaatagttga agggaaagaa ataaaaatgg
    34381 aattgacagt gggagataag gttatattcc aaaaatattc tggaacagaa gttaagatag
    34441 aaggacaaga atacacaata ctaagacaga gtgatgtatt agctgttatt gaataaatat
    34501 agaataaatt tattaggagg gatttaaaat ggctaaagaa attaaatttt cagaggaaac
    34561 aagaagagct ttagaagctg gtgtaaataa attagcagat acagtaaaag taacattagg
    34621 acctaaagga agaaatgtta tattagataa aaaatttggt tctccactta taactaatga
    34681 tggagtaact atagcaaaag agatagaact agaagataga tttgaaaata tgggtgctca
    34741 attagttaaa gaagtagcaa ctaaaactaa tgatgtagct ggagatggta ctacaactgc
    34801 tacagtttta gcacaagcta taataagaga aggtttaaag aatgtaacag caggggctaa
    34861 cccaatactt ttaagaaaag gaatacaaaa agcagtaata gtagcggtag aagaattaaa
    34921 aaatcaatca agaatagtag aaacacaaga ggctatatct caagttgctt ctatatctgc
    34981 tggtgatgaa gaagttggaa aattaatagc agaagctatg gaaatagtag gtaaagatgg
    35041 agttataact gttgaagagt ctcaaactat gaatactgaa ttagatgctg ttgaaggtat
    35101 gcagtttgat agaggatttg tttctgcata tatggttaca gatgtagata aaatggaagc
    35161 agttttaaat gacccatata tattaattac tgataagaaa atatctaaca tacaagaatt
    35221 attaccagtt cttgaacaaa tagttcaaca aggtaaaaag ttattgataa tagctgaaga
    35281 tgtagaaggt gaagcattat ctacattagt agtaaataaa ttaagaggaa catttgatgt
    35341 agtagcagtt aaagctccag gctttggaga tagaagaaaa gaaatgcttc aagatatagc
    35401 aatacttaca ggtgctcaag taatatcaga agaattaggt tatgatttaa aagaagctga
    35461 tttatctatg ctaggtagag cttcatctgt taaggtaact aaagaaagta ctacaatagt
    35521 agatggttct ggagataaaa aagctataga agatagagta actcaaatta aacatcaagt
    35581 agagcaaact acttcagatt ttgatagaga gaaattaatg gaaagattag ctaaacttgc
    35641 tggaggagta gctgttgtaa aagttggagc tgctacagaa gtagagttaa aagaaagaaa
    35701 attaagaata gaagatgctc ttaatgcaac tagagcagct gtagaagaag gaatagtagc
    35761 tggtggagga actgcttttg ttagtgttat accagcaata ggaacactaa ttgagagttt
    35821 agaaggagaa gttaaactag gtgctcaaat agttaaaaaa gcgttagaag agccattaag
    35881 acaaatagct ataaatgctg gtcttgaagg tgctgtaatt gtgcaaaatg ttgttaattc
    35941 tgaagcagaa actggatttg acgcattgaa tgaaaaatat gtaaatatga tagaagctgg
    36001 tatagttgac ccaactaaag ttagtagaag tgctttacaa aatgctgcat caatagcaag
    36061 tactttctta actactgaag ctgctgttgc tgaccttcct gaaaaagaag atgcaggaat
    36121 gccaggaatg ggtggcggaa tgcctggtat gatgtaattt aaaaaattta aaatataaat
    36181 tttaatataa agaactattt cgacttagat tttaaactct aagttgaaat agttcttttg
    36241 tatatatcta atttttgtat atctataaat tcaatacaca tatttagata atcagtatct
    36301 agtttgtaat aatattttag agtagtattg ttatttttta ggttatgatt ttagatatat
    36361 attaattaag gtataattgt tgatagagaa taaatcaaat ttaaaaggat gcgataatat
    36421 ggacttaaga aaattacttg aagaagttaa aaatgaaaat attgatatag attttgcgtt
    36481 agaaaagtta aaagatttac cttatgaaga ccttggatat gcaaatatag accatcatag
    36541 agaattaaga aatgggtatc cggaagttat ttattgtgaa ggtaagagtg atgagcatat
    36601 tttagggatt attgataaaa tgaatcaaaa aagttctaac atattgggga caaggtgcag
    36661 aaaagaaact tttctgaaaa ttaaagaaat ctataatcat gctgagtacg aagaggcgtc
    36721 taaaattctt aagattcaaa atcatgatat agagaatata ggaaaaggta aaattgtgat
    36781 tgctacaggg ggaacttctg atataccagt agcagacgaa gcttatcata cagctaagtt
    36841 tttaggtaat gatgttgata gaatatatga tgttggagtg gcaggtatac ataggctttt
    36901 aaataaaaga cataaaatag atagtgctag agtaatagta gccgttgcag gtatggaagg
    36961 tgctcttgca agtgtaattg gtggactggt tgatgttcca gtaatagctg ttccaacttc
    37021 tgttggatat ggagcaaatt ttggaggatt agcagcatta ctagctatgt taaatagctg
    37081 tgcatctgga atatctgttg taaatattga taatggattt ggagcaggat atttagcatc
    37141 aatgataaat aaactgtaaa tacattgata taaattaaac aaaactatat aataaaattt
    37201 aatttctatt atatttttac tattaaaatt gaggagacat atatgagtga aaaaatactt
    37261 tattttgata taataagcgg tatatcaggg gatatgaccc ttgcaagttt attaaattta
    37321 ggtgtgccta aggaaatttt tttggaggaa attcataaac taagaatgag cgatgaattt
    37381 aatataaaca tcagctcgaa aactgaaaat ggaatagtag gtacaaaagt agaagtaatt
    37441 acaaaagaaa aacatacaca tagaaattta gtggatatat ttgaggttat agataaaagc
    37501 actctaaacg aaaatgtaaa atctaaagca aaaaaaatat ttatggtaat tggagaagca
    37561 gaagcaaaag ttcatggaac tacaatagac aagatacatt ttcatgaggt aggggctata
    37621 gattcaattg tagatatagt aggagcttct atattagttg acttactttg tgtagataaa
    37681 gtttgtgcta gtacagtgtc tgttggttca ggatttgtaa aatgtgaaca tggaattata
    37741 cctatacctg cacctgcaac tatagaaatt ttaaaaggtg tgccaattaa attaaataat
    37801 gtaaatggag aatgtacaac tccaacagga gctgcaatca taaaagtctt gtgtgatgag
    37861 tttgtagatg agcttgaatt ttctccaaag caaattggat atggtatagg tcataagaag
    37921 tttgaagtac caaatatact cagaactgta ttaggtgaaa aaaaaaagaa gaattaattt
    37981 atgaaattag tgcaaacatt gatgatatgt cttcagaaat ctattcttat ttgtatgaaa
    38041 aaatattaga tgagaaagca ttggatattt atacagagag tatttatatg aagaagaata
    38101 gaccagcaac aaaagtatca attttatgta atgaatcaga tttagaaaag tttattaaaa
    38161 tattactttt agaaactagt acttttggag tgagatataa tgcatataat agagaaattt
    38221 tagagagaaa atttgtaaaa ttagatacaa aatatggagt ggttacagta aaactagggt
    38281 attataaagg aaaactagtc aaggttactc cagaatataa tgaatgtaaa actatagcaa
    38341 aaaatgaaga tattcctata aaaaaagtgt ttgctgatat aaattttaga ataaaagaag
    38401 aatttagtga aaacttattg acataagtaa taaattttga taaattaata ttcagcctta
    38461 ttaaataaaa gtaaacagaa aaaaatatat aaaatataaa ctcactcgta tatgctcaga
    38521 aatatggtct gagagtctct accaagatac cgtaaatatc ttgactatga gtgaaattat
    38581 tataccaaaa gacctagtta agtaaatgtg taggctgagt tatactccct atgtgttggc
    38641 tataagataa aggtattttg gaagcctgta tagtaatttc acttttgcta gaaattatgg
    38701 aagttactat acaggttttt tgtgtaaaaa gatttaatat aatttagact gtattgtgtt
    38761 aaaataaata tataaaaact atattataca aggagagatg tgaatttatg aaacatgaat
    38821 tagtacttgt aatagatttt ggaggacaat ataatcagtt gatagctaga agagttagag
    38881 aaaacaacgt atattgtgaa atacttccat gtactgcaag catagaaaga ataaaagaaa
    38941 aaaatcctaa agggataata tttacaggcg gtccaaatag tgcgtattta gaagattctc
    39001 caacaatatc aaaagaaata tttgaactag gagtaccaat acttggaata tgctatggta
    39061 ttcaaataat gtctcatgta ttgggtggag ttgtaagaaa aggtaataaa caagaaaagg
    39121 aatatggaaa aacatctata acttatggaa aatcatcatt atttgaagga ataactacaa
    39181 atagtgtatg gatgagtcat acagatttaa tagaaaaagt tccagaagga tttactatag
    39241 ttgcaaatac taatgattgt ccagtagcag ctatggaaaa tgtagaacga aacctatatg
    39301 gagttcaatt ccatccagag gtagaacact gtttggaagg ggacaagata cttacaaact
    39361 tcttatataa tatttgtaaa gtaaaaggtg actggactac agattcattc atagaagata
    39421 aaataaaaga attaaaagaa aaaataggcg ataaaaaagc tttatgtgct ttaagtggag
    39481 gagttgattc ttctgttgct gcagttctta ttcataaagc aattggggac aacttaactt
    39541 gtatatttgt tgaccatggt ttacttagaa aaaatgaagg aaatgatgta gaaagaatat
    39601 ttagagagaa atttgatata aatttaataa gagttaatgc agaagataga ttcttatcta
    39661 aattaaaagg agtttccgaa ccagaagcta agagaaaaat aataggtgaa gaatttataa
    39721 gagtatttga agaagaatca aataaattag gaaaaatgga tttcttagta caaggaacaa
    39781 tctatccaga tgttatagaa agtggacatg gaaatgctgc tactataaag tctcatcata
    39841 atgttggtgg aatcccagaa gatgtagact tccaagaaat tgtagaacca ttaagagagt
    39901 tatttaagga tgaagttaga aaaataggat tagagcttgg tatagaagaa ggattaatat
    39961 ttagacatcc tttcccagga ccaggtctag gaataagagt tataggtgat gtaactaaag
    40021 aaaaatgtga tatattaaga gaagctgatg ctgtttatat ggacgagctt agaaaagcag
    40081 gtttatacag agaaatatgg caagcttttg caacattacc agatgttaag actgttggag
    40141 tcatgggtga tgaaagaaca tatgcttatt tagttggttt aagagcagtt acttcttctg
    40201 atggaatgac ttctgactgg tataagatgc cttatgatgt attagaaaga atttctaata
    40261 gaataataaa tgaagttgat ggagtaaata gagtagttta tgatataact tctaaacctc
    40321 ctggaactat tgaatgggaa taaaatatag aatgccagaa atccacatga atacaggatt
    40381 tgaggtctct cttacttcta tattatactg gtttgatact atcaatattt gccagtatct
    40441 tatggattaa taagcaaaaa acatcctgct gaatggtaaa ttcggcgggg tgtttttatt
    40501 ttgttttgaa actcctttgc tctgaaactc gaagtattta acactgatga tgttgttatc
    40561 ttttagttcc ttttgtgtca tgctctgaaa gacaaattga tacaataaaa aagtaatttc
    40621 ttaatcattg atggagatat gtatttatgt tactcttgat ggtaatttga gtaatattgt
    40681 tcatagcttt ttatattcac ttaattagaa aaccatttgg tataatcata aataaacttg
    40741 atgatataat agaaaagatt tataattatt agaagtatat aaaagtattt tatgtctatg
    40801 aaatgtatgt ctataaaaca tatagatgac ttttgtatat taatgtatga atattgatat
    40861 tatagaagaa ttgagttgtc aatgatacta aatcaaatat ttatagaaga tggagggatt
    40921 atgagaaata aaataattat aggaattact ttttcacttg tattactaat gtctggatgt
    40981 gcttcaaaac aaacagcaga aataaacgta ttagcaacta ctgatttaca tggagttata
    41041 ccttatgagt taacttctta tgtaaaagaa gaaagaaaaa aagataaaaa tctaacttta
    41101 gtagatgcag gagatttttt tgatagtgga gaagtgtttg gttctagcat ggatagttat
    41161 tttagtgcta gatataaaga tggtgataat aacactgaaa gttatattga gacgcctatt
    41221 tcaaaagata tgaaagaggt aggttatgat gttgcagttc ttgggaatca tgaatttata
    41281 tccaacaata aattttatct agataatatg atatctgatt ttgagaaaca aaaaataaat
    41341 attttatcgg caaatacgta taaaaaaaat ggagatagtt atacaaaacc atacataata
    41401 aaaaatatta atacacctga aggaaacgta aaactaggaa ttttagggct tactataaaa
    41461 gaagttggtg agaggaaaca gtggaaagat ggaaaacttg ttgactctaa gtctttagaa
    41521 ctaaaagacc aagagggcta caatggtgaa ttgtatatga atgatttagt agaagatgct
    41581 aaaaagtggg ttggtataat ggaaaaagag aagcctgaca ttatagttgc tgtggcacat
    41641 acaggtgaga aacctaagaa acctagaaac ccaggaaata gaatacaaga cttagctcaa
    41701 caagttgatg gaattgatgc tatagttgca ggtcataatc atgttcaaat tgagcaacat
    41761 gattataaaa ataaatcagg agaaaatgtt atagttactg agccaggaaa gcatggggaa
    41821 tatatttcta agattaattt taaattagaa aaaaacaatg ataaatggaa tatagttgac
    41881 aaatctagta aattaattaa atttgaaaaa aatcaagaaa gtgataaatt tggagaattt
    41941 atttcttcaa ttaataaagt aagtaaagat aagaaagaaa taagattatc agaagtaaag
    42001 actcctgaat gggataaaat atatgttttt aaatctggaa catctgcaga tgatatatat
    42061 aaaacaatag gatataaatg gagaaatata tcatctccaa agggtgatga catggtgcag
    42121 attgttgtaa tgaataataa taagcctgtt agctatatat atggtgaagc tgaagttatg
    42181 ccaattaata taaaatgtga tgaatcagag tataaaaata atgttgtaac tatttatcct
    42241 aataaaaatg ataaatttaa aattgaaaaa ggtaagcaag aatatagtat taatttaaaa
    42301 catatacaat agaaactttt atcttattta agtttagatt gtacttaaaa taaagtgtgt
    42361 attattttaa aaagtgatga taattaaaat cacaacatta aggaatagta cacacttttt
    42421 atgctaaaaa atagaatgtt aaaaaattaa acctttaaat taaagtacat tgcttatatt
    42481 atccaatatt atttccaaag gttgtgtaat atttttatcc ttatgtaata ttgctaacat
    42541 tttattttcc atatctatct catctaattc aatcaatcgc aattttttat gtaagagtga
    42601 atctaataat aaattttctg gcaaaatggt tatacctaac cctgcttctg cagctttaat
    42661 aagtgcaaaa gaattaacac tttcccaaac aggataagct ttttggtttg aaagagataa
    42721 tacactgtcc aaagtatcgc gaatagcact tccttgttca cgtaacaata acggaaacgt
    42781 gcataactgt cgtagagata aggtttgttc agataaagga aaagttggag cacatgcaac
    42841 acataactta taggaaccta ataaaattgt acggaatgcc ccctgtggtt ctataccttc
    42901 ccaaaaacat atatcagctt ctccactttt taaaatatcc atagctgaat tagcactttc
    42961 gacacgtaca ttcactttaa gagatggaaa tgaatttttt agtcgactta aaattggtgg
    43021 aagtaaaaaa gaggcaattg taatgctaga aacaatgttt ataggtgtac attcttctaa
    43081 acgactgatt tttttgtcta aattgcgaca agcagttaag atactacgtg cttcatctaa
    43141 aagagaaatg ccacagcgag taagacatac ccctcgtggt aatctgtcaa atagtgatgt
    43201 ttcagcttgt tgttcaagtt cagctatagc atgagataca gcagattgtg tgatatgtaa
    43261 tttttttgca gcacctgtaa aagtgcctgt ttgttcaatt gcttctaaaa tctctaaata
    43321 tcgtatgttt atcataataa atatcctcac tatacatgaa taaaattaat taattccatt
    43381 aaattctatc attttacaga ttgcaaagca acaggtatac tgaataatat gaagtgaaaa
    43441 gaaggaggaa tattttgaat caaagcagaa aaatatattt ttggctttta attattaact
    43501 tgtttattag cacattcact tttggcggag ggtatgtagt tgtacctatg attagacgtt
    43561 attttgtaaa tcaaaagcaa ttctttacag aagatgattt gatgagtatg gcagcagttg
    43621 cacaatcaac tcctggagct attgcaatta atttatctgc tttggcaggt tatcgagtag
    43681 ctggtacttt aggggttgtc attagttgta cagcagctat aatacctcca ctcgttattc
    43741 ttggattagt atcagcattt tacaccactt ttatatctaa tgccattgta actgcagtat
    43801 taaaaggaat gcaagctggt gttgctgcac taattgtgga tttgattatt gacatgtgct
    43861 ctatgatatt aaaacaacgt tctttgtttt tatcaactat gatacctatt gctttctttg
    43921 caaactttgt gatgagtata aatgtaattt ttatattatc tgtttgctgt tttgtatgtg
    43981 taatgcaagt tttctataag aagagggaaa ataaatgaat acaatttgga acttattttt
    44041 tatattttta aaaataggct tgtttagtat tggtggtggt tatgcaatca tacctttaat
    44101 ccaagagaaa gtagtaaatc aaactggatg gataagtgag aaaatgttta cagatattat
    44161 aactatttca caaatgacac cagggccact ggctgttaat acttctactt ttgttggact
    44221 tcaaattgga gggttttggg gagcagttgc agccacttta ggttgtgtat tatgtggtgt
    44281 agtaatatct ctatttttat ataatttttt tcaaaagcat cagaactcta cttatatatt
    44341 tgaaatatta aatggtctaa aatcagcttc attaggttta attatctcag ctgcggctac
    44401 aattataatc cttgcattat ttgggacgaa taaagtgtac ttcaattcta tatttgagat
    44461 gctaaactgg actgcactaa taatcttttt tgttatacta ctgatagtac gtaagtggaa
    44521 aattaatcct attgtgatta taataataag tggtatacta ggaatatttt tttatttata
    44581 agtttttggt aagtaaagga tatctatttt tttatatctt aaatccaaat agccaataaa
    44641 gtaaggctat ttggattttt aataaattct gaaaagataa tcagaaaccc atataacatt
    44701 taaattatat cactggtttt ctacaaacca atcataagct tcttggcaaa atttctcact
    44761 atctatatag taactattat gaacattatt aatttcaaca agtttctttt tacattttag
    44821 tgaattataa tagctatcaa aatattgggt tttaaaatat ctatcatgaa gtgttttaaa
    44881 gacaagagta ggtatgttga ctccatcttt tatcttacta tcttctgcaa taaagcattc
    44941 taacattgta ttaattatct ttgtactatt tttccaaata tgaggatttt tcttttcaaa
    45001 tattttataa aattcattat catagacttc attataacct ttatatttag gtggttttac
    45061 tgttatgtga aaattaggaa gaaacttaaa gaaaaaatat aataattttt atgttctgtt
    45121 ttatatatta ttcatatttt atcacagata atatactaaa gttaattttt ttattgtaca
    45181 actattataa taattcttct ataatataag acattctata attttatatt taagttcatg
    45241 tgtatttaat tgtttttata taaaatgtcc agtaatacta tttggattta tttttatttc
    45301 atcaggagtt ccagaagcaa caatttcccc tccatttatt ccactgtctg gacctatatc
    45361 gataatccaa tcagaagcac gtataacctc tgtattgtgt tcaataatta aaagtgaatg
    45421 ctgttcattt acaagttttc taaaagtaat caacaaattt tctatatctt taaaatgaag
    45481 tccagtagta ggctcatcca atatgtacag cattcgtttt ttagtttttg tccctaattc
    45541 ttttgctaat tttatccttt gagactctcc tccgcttaat cctaatgtat tttgtccaag
    45601 ctttagatat ccaagtccca cttcatctaa taaggagagt tttctatata tatcagagca
    45661 atcactaaaa aatgtttttg cttctgctac ttccatgtca agtatatctg caattgtttt
    45721 tcccttgtat tgtatagaca gtatttcttt ttgatatctc ttaccttgac attcattaca
    45781 agttacccat tggtctgcca tatattgtag aataattttt gttttaccta atccttgaca
    45841 gtttgggcat tgcccctttt tgctattaaa gctaaaatag ctttcatcca ataatttttg
    45901 ttttgcttgt ggagtttcag taaatagaga acgaatttca tcaaaaatat tgatatatgt
    45961 agcaggtgta gaacggctag attttccaat aggtgtttgg tccattaaga taaaatcgtc
    46021 aatagcatca aatccagtaa gtgcagtata atttttattt gggatagatt tttgtttcaa
    46081 tttttcttct agagcaggaa gtaaactgtg aaatacaaga gaactcttac cagaaccact
    46141 aacacctgta atagagcaca tacagtttaa gggaatttct acatcaatat tttttaagtt
    46201 atttgcatgg catcccttta agcttaacca tttacttggt ataattttat tttgtgaact
    46261 tatcttattg tatgtactca aatatttgcc tgttatagaa tttggatttt ttataatttc
    46321 ttgggttgta ccttctgcaa tgatgaagcc cccttttgta ccagcatttg gtcctacatc
    46381 aataatataa tcagcagaca gtattgtatc cttatcatgt tccactacta taacagtatt
    46441 acccttgtct cttaattctt ctatcatttt gatgattaga ttatggtctc ttggatgtaa
    46501 accaatagat ggttcgtcta aaatataggt taatcctact aattcacttc ctagctgact
    46561 tgataatcgt actctctgca gttctcctcc agataaagtt ggagctgttc tatctgttga
    46621 tatatagcta agacctacct ttaatagata actaactcga atttttaatt ctgttaagat
    46681 atcatttacc aaagatagct catttttttg aagttgattt ggtaattcac acaaccaatt
    46741 ccataactgt tctatcgtca tttttgttag ttcagggaag cgataacctt tgattgtagt
    46801 gaatctagcc tcaatgcaca gcaattcgcc accacatgta ttgcaaggaa ttttgttcat
    46861 atattgatgc aaggtattat tttcagaact agattctcta aaaagtcttt gaatgtggtt
    46921 gattgctcct gaagcaggcc ttctaatctt tgattctcgt ccctttgatt caaagctaaa
    46981 ttcatatatc ttatcgtctg taccatataa gattgcatct ataaaatctc ttggcaattc
    47041 attccaaggt atatctaggt ctatattttt atcttttgct attgcatata attcacctac
    47101 catccaatta ccatttggct ttttccccct caattttcca aaatagtaag tagctccatc
    47161 taatattgaa atagttgggt cttttacaat taattgagga ttaacttgat aggtaaaacc
    47221 caatccatta caatcgtgac aagctccagt atgggagtta gcattgaagg ttgaagtatt
    47281 tatcttagaa aaaatagttt ggcaatgtgg acaataattt tttgtattat tctttttttc
    47341 taatggagtt ttgcaatatg gacagtaact ttttccgatt gatacaaata acattcttaa
    47401 gtaatcccaa atgcttgtaa gagtaccaac agtagaacga ggattttggc ttcctttttt
    47461 ctgttcgata gctatagtag gggttaatcc ctgaagtaaa tcaaattccg gtttttgaag
    47521 ctgttctgaa agttttgctc cattacctag attttcaaaa taacgtcttt ttccttcttc
    47581 ataaatcgta tcgaaagcta aagaagattt tccactacca cttacacctg taataacagt
    47641 tatttgattt tttggaattg taacctcaac atcctttaaa ttgttttgcc ttcctccttt
    47701 tagatagata gagcttttat tatgacaaag tgaattttta attgatttat ttattgcttt
    47761 tgcaaatttg aatttctttt ctagttcaag aggattgcct aattctttta tttccgaaat
    47821 acctaatatt tttaactgag aaaagattga tttcaaataa tcttcaggca atttttctat
    47881 taacaaatta aggtcttcta tttttatatt tccgcttgat aatatctctg ccatttcatc
    47941 taataaattt ttttctgctc ttgttaattg attgtatttt ttggaactta attctgtcca
    48001 taaatcccat ggaagcaatt ctaaaccaat catattatta aagtcatgta gaagattacc
    48061 ctttacagaa tgccaacctt tccaattttt attatatcca aagtcatctg gatgagcatg
    48121 tccttgtcga catcttatcc aggcttctga accagttaaa aaaccatctg tttttccgac
    48181 atcatgagtg tcaaaattaa tttgaaaata atttttttgt atgtcatcta tttgtgcatc
    48241 tattcttatc catctctttg ttagagtatc atagtattct acaagccagt ggtcttcata
    48301 agtaagctca ttttcaaaat aattagcaaa acctgctctc attctagcct caaaacctcg
    48361 atatcttagg agcgatacaa gaagtaaaga ataatctctg cacattccaa caagcctttg
    48421 ttttgggttt cttggaatag ttagtgggtt agaatttatt tcaaatattc tttttaacat
    48481 ttgaggaatt gtacgaagca attcctcatc agattgttgc ttattaaagg atataccata
    48541 taattttcct tggtctccat gaattactag gctttgaacc acttttaata actcaattgg
    48601 agtctttggt aaatcttgat atttattttc aaatttttta ggatttgtga tgatgctttg
    48661 atttttatag ttatttattt tcatttatat ttcacctctc taaatggatg atataccctg
    48721 acatggtgtc atatgcaagg acaatttaga ttttttggcc aaaatttaaa aataaataaa
    48781 aaatgataca gtgataaatt gtaatacaaa tatagtttca aattgcatat aatataatta
    48841 tttaataaaa ccattatcta tggaatgtta atgaaatgtt aagatggcat tcttgaatat
    48901 taagaaatag aatactataa tatagtgtga aggattctta gtaaaaaaat ttgtaagtgt
    48961 taatatacat taaaaaatag gtttataatt tggaggaaaa aaatgaaatt atcaaggtat
    49021 aagaaaaata gtttagttct gtctataatt ttatgttcac ttattatttc aatccttgta
    49081 attactgttt ttaataccgt aaaactacac aatatatcta ataaacaatc taaaaactat
    49141 ttaaacgatg tatctacaca gattgtaatg aatgttgatt ctaaaatcaa atttatttta
    49201 tccgacttaa gaataatggc agattttatt aagcaatatg aaggtgatag tcgatatgag
    49261 tatttatcta aaagaaagac tagttataag tattatgatg ttggaataat agatttagaa
    49321 ggtaaagctg agtttttaag tggaaaaaag tttgacttaa agaatactgc ttcctataaa
    49381 aaaggaattg aaggtaaaga atactcagaa gtaatagagt caatgggttt tgttctttat
    49441 agtgtaccta tatttaacga taatcatgaa gtgtctagta ttttaatagg tgtatccaat
    49501 aaagaaagca tggatgagat tcttaatata gatagcttta atggagaagg aactattgaa
    49561 attattaata gtcagggaaa aactcttttc ataggaaaaa ataatgagtt aataaaagac
    49621 cttagctata agtataagga ttctgcagat gaaccttggg cacaaaagat gcttaatgat
    49681 tttaaaaatg ataaatcagg aaatattaca ataacctcat caaaaggtgt acaatgctta
    49741 ttaacttatc atccaattac aagaggttta aatgattggc attttcttct catagtacct
    49801 gaagatgttg tacttggtga acttaataag ttaaattctt ttacaataat aatgacattt
    49861 ataactacat gtattattgg aattataaca ttaattttat atattataag aagaaaatat
    49921 gtaaatcaaa tagaaaatat tgcatattta gatagtataa caaatggtat aaattcaact
    49981 aagtttagta tgctagtcaa acctttaatt tcagaatcac ctgatagtac ttatatgatg
    50041 atagcaatga atataaaaga ttttaagcta ataaatgatt gtttcggtag tgaaaaagga
    50101 aatatgacac taaaacatct ttacaatatt ttgtataaaa acattgatga aaatgaagaa
    50161 tttgtgtgcc gtcatgatgc agaccttttc tatttgctta ttaagaatag accagtgtta
    50221 gaagccctgg agttattata taaaatagaa gctgacacaa attattttaa taaaaatagg
    50281 gaaaatccat actttttaag actatcagta ggtatttaca caattgaaaa tcataatgaa
    50341 gatttaatta caatacaaga ccatgcaaat acagcaagaa aaagctttaa taaaactcat
    50401 caaagtgatt tttcttttta tagtgatata gaaagaaaac gattaatatc tgaaaaagaa
    50461 atttcaaatt taatggaaaa agcccttgaa aataaagaat tttttatgtg cttacaacct
    50521 aaaattgata taaaaagtgg aaaaattagt ggagcagagt ctcttgtgcg ttggaaaaat
    50581 tcagaaaagg gcataattta tccaagtaat tttattcctc ttttcgaaaa aagtggattt
    50641 atatgtaagt tagatttata tatactagaa gaaacatgca aattgatttc taagtggata
    50701 aaagaaggta aagaagtgtt gagaatttct gttaatgtat cacgtcaaca tttgaatgat
    50761 aaattgtttt tagaaaaata taagcatata tgcaataaat acaatgtacc aacatgtctg
    50821 atagatttag aacttaccga atctattttc ttagaaaatc cagaagctat agatataata
    50881 gaggatattc attctaatgg atttaaatgt tctatagacg attttggatt tgggtactca
    50941 tcattaggga tattaaagga ttttaaagtt gatataatta agttagaccg ttcattcttt
    51001 gttagcaaaa ataatataga ccgtggtaag gtagttatta agtctattat tgaacttagc
    51061 aaaaggctag gtatgaaagt aactgctgaa ggaattgaag aattagaaca agttgagttc
    51121 ctaaaaaatg taggatgtga ttatattcaa ggttatgttt tttctaaacc attattaatt
    51181 tctgattttg aaaattttgc atatgaaaat aataaaatta aaaatatcca ttattaaatg
    51241 tacaagataa aaaatttagg caagttatat aattaaaaat ataacttgtc ttttttattt
    51301 atatatttaa taaaaatata tttgcagatt ttgtaaaaat aattttcaaa tgttgtaagt
    51361 tgtggctaaa gctttattgt attattctga atatagaaag atagttactg tcttagataa
    51421 aaactgaaac atacataata atataaaatt tgctatatta ataactctaa ttattttgga
    51481 aggagggaaa atatgataag tgggagaatg ttactcatca tgaattttct aaaaggaaaa
    51541 aataagacaa gttacaagga tattagcaaa caacttagta tagaagaaag aaaagttaga
    51601 tatgatataa ataatttaaa tattgttttg cgttcattaa acaagtcagt aatacaaaag
    51661 atgaacaaag gtgtgttaat tattcctgat gacttccaag tagtatgtat aaataataac
    51721 gaatatgtat tttccttaac tgagcgagta tctattatga aaattatatc aatgtttaaa
    51781 atagataatc taaacttaga aaaattgagt aaagaatttc aggtttctag aagttcaatt
    51841 aaaaatgacc ttaatgtttt gtcaagtgaa ttagaaagaa accaaataac tattacttat
    51901 gataaatctt ttaaaataag tggagaagaa gaccttatat ataagcaaag attgaacata
    51961 ttaaaatcgt attcttatct ttttggtaag gaaaaatctg atttaagtgt atttgagaag
    52021 tatttagtga atgtaattga aaaaatattc aaagggattt atttgattga tatatataat
    52081 tggtctatga atttattatt gcaaatggga tggactttaa atgatgaatc ttttacatgg
    52141 tatgtgtcaa acattttcct ttttacatgg tatatacatt cagatgaaaa acatccttta
    52201 gaatctgctt cattaagtga gccatgtttt gaaaataagt ttgaccaaga atttgaaaca
    52261 attattcaaa aaaagttgac taaggaacaa atttttctgt taaagagttt tgtatttttt
    52321 acaaataaat atgcaagttt aaacgaggat atggatttga ttagtacaga aattatagtt
    52381 caagacctaa tttacaatat gtcagaaata ttagagatta gctttaaaga agatatgatt
    52441 ctttataaag gattactcaa tcatattgcc ccattgatag agagaatcaa gcagaatata
    52501 cagatttatg aggaattact tcatgtaata ccagataaat atcaatatgt acttgaagct
    52561 actaaggttt ctattcaaaa aaacagagtt ttaagtcaaa taaagaatga aaatgaaata
    52621 atacttttgg caatacattt cttaggaagt atacatagaa atgagaggaa taactacaaa
    52681 aatatattgt tagtttgtgg atttggatat ggtgtaattg ctatgttaaa ggatagttta
    52741 gtaaatgatt accagataaa tatagtagag agtattccat catataagtt acaagattat
    52801 aaagaatggg aaagtattga cttcattata acaacatcaa agatagtaat agacttgcct
    52861 aaaacaatta ttgagataaa tccattttta caagaagagg attatttgaa gtttgaagaa
    52921 aaagggataa aaagaaagaa cgtcttaact aattatatgt caataaaaaa aaggttggac
    52981 tttttagaag aagatgctca aaaaagagta ttaagtatta tatgtcaaga acttggatac
    53041 agtgatgaga gaatattatt tagacaactt aatttaagtg atttaatagg gattgatacc
    53101 ataaggataa ttgatgaaga tatgaaatgg gaagatgctg taaaaattag ttcaaacata
    53161 cttgctaatt gtgattttgt atcagcacaa tatgctgaga atattataga tattttaaaa
    53221 aatgtgggtt tttatgctgt aaaagataac gaatttgctt tactacatgg caatgatagt
    53281 tcattagtca aagtaagttc gataagttta ttaatatgta aagaagcagt tagttttgga
    53341 gataaaaagg ttaaaatcat attttgtcta gcaagcagag ataaaaaaga gcaaattcct
    53401 gcaataatta atctaactaa aatggtttat aagactaatt ttattgctat gttagaaagt
    53461 gcaaagacaa aagaagaagc agaagtttta attcataaat atgagaagga ggtcactgta
    53521 tgaataaatt agttaatgta aaatgttcat ttaaaataca tgctaattca aaagaagaag
    53581 ctattgtatc gttagttgat gtagtatcaa aagaaggata tctaatagat aaaaatcaat
    53641 ttttggaaga tgttttaaag agagaagaaa cattgtcaac ttatattgga catggtatag
    53701 gtcttcctca tagtcaaagt gtaggtgtta aaaactcttg tattacaata ggaaagcttg
    53761 atattcctat tgaatggaca gaagaaggag aaaaagtgga tttaatattt ttaatatcag
    53821 taacaaaaga caatgaaaat aatcttcatt taaagatttt atcaaaatta gcacgtttat
    53881 tgatgcatga aagttttaga aatcaaatta gatgttcaga tgaacaaact gtttataatc
    53941 ttataaaaga aaaaatagag gaggaagatt aaaatgagaa ttttaaagtt tttgcaaaaa
    54001 catcttatga cagcaacatc ttatatgatt ccatttgtgg ttgcaggagg aatattattt
    54061 gctttatcag taactctaag tggacaagct gctgttcctg aaacaggctg gttggctaaa
    54121 ctgaatcaaa ttggagctgc tggcttggct ttattcattc ctatattagg tggatatata
    54181 gcatttagta tggcagataa accaggatta gctccaggta tgataggtgc atatttagca
    54241 aaagaagtaa atgcaggttt tataggtggt atcatagcag gatttatagc aggatttgtt
    54301 gttttacaat taaagaaaat taaattagct cctacaatga gaactttagg ttctatattt
    54361 atttatcctt tgattggtac attgattaca ggtggtataa ttgtattttt aattggagaa
    54421 cctatagctt cttttatgac atggatgaca aactggttaa atggaatgtc tggtgtttct
    54481 aaaattcctt taggtggaat cttaggagga atgatagcct cagatatggg tggtcctata
    54541 aataaggttg ctgctacttt tgcccaaact caagttgaca cacttccata tttaatgggt
    54601 ggagttggcg ttgcaatttg tatacctcca attggtttag gattagctac attattgttt
    54661 ccaaaaaaat ttagcaagga agaaagagat tcaggtaaag cttcgctatt aatgggatgt
    54721 gttggaatta cagaaggagc tattccattt gcaacatcag atccagttag agtaatacct
    54781 tgtattatgg ctgggtcgat tataggaaat attatggctt ttttattagg atgtttaaat
    54841 catgcaccct ggggaggtct gatagtatta cctgtagttg acaataggtt ggggtatatt
    54901 gcatcagtat taactggagc agtagttgtt gcagtattaa tgaaattagt aaaaaaagac
    54961 gtgaaagaag atgaagaaat tgaagaggat ttagatgaat caattgaatt aatatttgaa
    55021 gaattataaa tataaatgga aggaatttgt ataaaaaagt aaatataaaa ctataaactt
    55081 aaaggagata agaatatgaa aattgtagca gtaacatctt gtcctagtgg agtagcacat
    55141 acttacatgt cggctgaatc acttgaatta tcggccaaaa aatttggtat agaaataaag
    55201 gttgaaactc aaggaagctc tggaatagat aatgaattgt cacttaaaga tattgatgaa
    55261 gcaacttgtg taatattgac taatgatgtt gagattagaa atatggaacg ttttaaggga
    55321 aagaaggtag taagaatgag tgtatctgag ataattaaga aatctgatgc attaattaag
    55381 aaaataaaag atacttttca ataaaaattg atttatttta catataactc aaagatgttt
    55441 ttaaagaaat ttttattaaa agcatctttg aaaatatctt aaaaatagaa taaaaggaga
    55501 tatagtcatg aaaaaattac caataaagac tgtcgtacaa agattactag acttacaaga
    55561 agaggggaaa agtgcaactc ttttaggaat tggtcctatg tcaccaaact tgttacaagc
    55621 aagttttgaa ctagcaaaag atgatgattt tcctttaatg tttatcgcaa gtagaaatca
    55681 agtagatgca gatgaactag gtggcggtta tgtaaatggt tggaatcagg aaacttttac
    55741 aaaagatatt aagaagattg ccgacaaagt tggatttgat ggtttatatt atttatgtag
    55801 agaccatggt gggccatggc aaagagataa agagagaaat gaccatttgt ctgttgatga
    55861 agcaatggag ttaggaaaaa aatcttattt agcggacatt gaagcaggtt ttgacctatt
    55921 gatgattgac cctacaaaag acccatttga aattggaaaa gtaattccac tagatgtagt
    55981 actagaaaga actgtagaat taattgagta ttgtgaaaac gagagaaaaa gacttaatct
    56041 accagacata ggttatgagg ttggtacaga ggaaaccaat ggaggtctta cttcaactga
    56101 gacgtatgaa acatttataa ctagactaaa ggttgaactt gataataggg gtttgccaat
    56161 gccaacattt atagttggtc aaactggtac tttaactaga aagacagaac aagtaggaac
    56221 ttttaatttt agaaatgctt atgatttagc tcaaatggct aagaaatatg gagttggttt
    56281 aaaagagcat aatggcgatt acttagatga tgtaacttta ttagaacata taccatctca
    56341 aattattgct acaaatgtag ctcctcaata tggtactgaa gaaactaggg catatttaaa
    56401 attagcagaa gttgagtgta aattagaaaa agagggccta gttgataaaa cttctaatat
    56461 cagacatgtt cttcttgtta atgcaattga atgtggacgt tggagaaaat gggtagtagg
    56521 agaacaaaaa aatctaacta ctgaagagat atttaagaat gaagttttat ctaatgaaat
    56581 actagatatt gcaggacatt atacatttaa taatgatgat gttaaaaaag aaatagaagt
    56641 gctttatgat aatttaagta agaataatat tgatggtcaa agatttgttg tagaccatat
    56701 taaacgtcct ttgcgtgatt atgcagaatg ctataactta aaaggtgtta ctacgaggat
    56761 tttaaataaa taataggact tatagtggtg agtattgtta tactaggtat ttatagttat
    56821 aattatactt accactatta aatttaggag gactaatatt ttgattaatt taatttttga
    56881 tgtagatgat actttatata accaattaac gcctttttac actgcatata ataaagtgtt
    56941 ttcttcaata aaggatattt ctattgaaga tttatatatg agtagtagaa agtatagtga
    57001 tgaggtattt catatgactg aaaatggaga aatgccaatc aaagaaatgc atatttatag
    57061 gataatgaaa gcttttgagg agttgggaaa ttctattaca gaaaaagatg cacaaagttt
    57121 tcaagatgag tatatatatc agcaatcaca aattacacta ataccagaag ttgagaggat
    57181 tttaaatttt tctaaagaaa gaaatattaa tctaggaatt ataactaatg gcccatcaaa
    57241 ccatcaaaga atgaagttaa agcagttaaa tattgaaaat tgggttgata aaagtaatat
    57301 ttttatttct agtgaggttg gattttctaa gccagatact aatattttta gagtagctga
    57361 gaatgttatg aatttagata gagaaaatac atattatgtg ggtgattctt atagaaatga
    57421 tgtattaggt gctaaaaaag ctggttggaa gagtatatgg ttgaaccata gaggacatga
    57481 ggtagaagag ttgttttata aacctgattt tgtaattttg gaacataagg atttgatatc
    57541 tttatttata aaaatatgta gttataaaaa tatgtagtaa aaaaatgtta ataatagaat
    57601 tgtataaaat aattaataat aactatataa aattatatgt ttagattgtg agcaatctat
    57661 tttatgttaa aaatagatta tttagaagaa ggggaaatct taaaaaaatt tgaatatccc
    57721 ctttttatta tttaattaaa atgaaatagt tagaaatata ttttatttag tttagtcaat
    57781 aacattttgg gattctttat aactacatgt taactgttga ataggcttat catatggttt
    57841 aacccatcct ttattaatac ttaattctgt aagtgctgtg tgaccttcta ccatttgagt
    57901 tagtgaagct gaatatatag ctcttaattc aggtgtacta cttgttaatg cagaattaag
    57961 atacatattg gcagatgctt tagcagatga aagcatactt aacattatta ctttatcgtc
    58021 tatataagta ttgttcttaa ttagattttc tatcatattt ctcatgttat ctatacctcc
    58081 tcagaaatta gtatttcatt ttcaactata aattgttgta tagctttaat tcttccttct
    58141 gttgctaata tactagattc tgattgtctt tttaggtctt catctgatat taacatattt
    58201 attgctcttt gcataagtaa tccgtcagac tccattttta taactgctgc taaagatatt
    58261 ttttcagttt ctgaaagtgt tctcatttaa tcatctccta tattgtaatt tatgctttaa
    58321 tagtatgtct ttcttttcaa ggaaataacc attacacttt tttacagtat tttatattct
    58381 ctttatatca aagtttagtc aacttaatat attaatataa ttttgtagga tatttatcat
    58441 taaatatcta taaaataaat tatttgaata ttcataaatc aaaatttatt tgtatgtact
    58501 tcttcaagag tcaatatgaa ttttttcaaa aaattaattt tgatgataat cattaagggc
    58561 tatatttttc ctaaagttgt gattatcatt attaatttac taaaatactt taatgaaaaa
    58621 tagctaactt taattgtagg atattcttaa tatatttgaa ataaataaaa atattgaagg
    58681 atataatatt caattggtat ataaataata aatgatagtt aagatttacc ttagaggcta
    58741 attaggtgtt cagtcaaaat taatgccttt agaatacaaa tgtattctaa aggcattttt
    58801 actatgtatt ttcatttata ttactaaaca ttatctattt ttatatacat ttctatgtat
    58861 tttattttca tcaaatcggt ctataaattc atttttttct tcactatatc caatagatat
    58921 aagtgcataa ggaactaatt ttactggtaa gtctaaaatt tgtttaactt tatttactac
    58981 tttattttta ggaaatactc ctgcccaaca agcagctaga ccttgattag taacttctaa
    59041 taataaattt tgtgtgcaag cacctaaatc ttgtatccat ttaccaggtt ttaagaattt
    59101 atctctattt ccaagcacta ctatacataa tggtgcaaat tctatatgct ttgctctatg
    59161 ctgtgacttt gagagctctt tcagcagttc cttatcatct actataataa attcccaagg
    59221 ttgagcattt tttgatgaag gtgcttgcat agctgatttt agtatttcag ttattttatc
    59281 ttcttctata tttttatcta tatatgttct tattgaacgt ctatttttta taacttctaa
    59341 catacagatt ctcctttaaa taaaattatt tctatttata taatatcatt actttaagtt
    59401 ttagctatta cttatataaa gaataaactt tgtgttggtt ttatctaagt aaaagtaaca
    59461 ttcagaacta aaaaacaaga ctataaatcc aagatattaa ttaaaaaaga agtaataaaa
    59521 aataatatac aagatttaaa aaagagtatt gagcttaaaa tttaattaga aaaccaattt
    59581 tgagataatc tgttttttat tttaacaaaa aaacataaat aaagttcgat acgtagcgaa
    59641 tgaaaaaaat acaagaaata ttttttttaa aaaatttcaa aaaagagttg ataatatatg
    59701 tatattaata taaaatttaa ggtgtataat tcgtataata atacgaatga tttgtagtgt
    59761 aaaataactt ataaacggag aggggaagtc taatgaaagt agcagtagtt atgggttcaa
    59821 aatcagatta tccaaaatta gaagaaggga taaaactgct tgaaaaatat ggaatagagg
    59881 ttgtagcaag agcattatca gctcatagaa caccagaaca actttcaata ttcctaaaag
    59941 aaatagaaga tgatactgat gtaataatag cagcagcagg aaaagcagca cacttaccag
    60001 gtgtaatagc ttcacaaaca ttaattcctg taataggatt acctattaaa tcatcaacta
    60061 tggatggact agactcactt ttatcaatag ttcaaatgcc aaaaggaatc ccagttgcaa
    60121 cagttacaat agacttaggt ttaaacgcag ctttattggc attacaaata atgactttaa
    60181 aatacccaaa attaaaagag gatttgaaat catatagaga agagatggca caaaaggtgt
    60241 tagaagacga caagaattta agggggtagc agaaatgtta ttatatgaag gaaaagcaaa
    60301 acaagtatat tctacagata atgaaaatga atatgttgtt tattataaag atgatgcaac
    60361 agcatttaat ggagaaaaaa aagcagaaat atcttcaaaa ggtatactaa ataataagat
    60421 atcaacaata atctttgaaa tgttaaaaga aaataatata aatactcact ttataaaaag
    60481 tttatcagat agagaaatgt tagttaaaaa agtagagatt ttaccattag aagtaatagt
    60541 aagaaatatt gctgctggtt ctatctgtaa aagagttggt cttgaagaag gtgtagtttt
    60601 cgatgagcca atttttgaaa taagttacaa aaatgatgct tatggtgacc caatgctaaa
    60661 tgatgattat gcagtggcaa tgaagttagc aactagagaa gagttaaaat tcttaagaga
    60721 agaaacttta aaaataaacg agttactaaa agcatttttc ttaaaattaa acctaaagtt
    60781 agttgacttt aaaatagaat ttggtaagga ttctgaagga aatataatat tggcagatga
    60841 agtatcacca gacacttgta gactttggga tgtaaataca aatgaaaagt tagataagga
    60901 cagatttaga aaagaccttg gagaccttgt agaaggttat acggaagtac tttcaagaat
    60961 gaataataaa taggaggcaa atgtatgtgt ggagttttag ggatttactc taataaagat
    61021 gtaactaaag aactatatta ttctttatat tctatgcaac acagggggca agaaagctgt
    61081 ggtttagctc ttttagatga tggagaaatt aagtacaaaa aagatatggg attagttgga
    61141 gatgttttta aggaaaatga attatctaag ttaaaaggaa atatagggat tggacatgtt
    61201 agatattcaa cagctggagg aagtcatgtt tctaactgtc aacctttagt tggaagttgt
    61261 agaaaaagac aattagccat agctcataat ggaaatctag ttaatgcaaa ttatttaaaa
    61321 gatatgctag aagaagatgg atatatgttc caaactaatt cagatacaga agtgatttta
    61381 tatatacttg ctagatatta caaaggggat atagtagaaa gtttaaaagt gacaatggat
    61441 tatataaaag gtgcatatgc tcttgtaata atgagtcaag aagaattggt tgcagttaga
    61501 gacccacatg gattcagacc tcttgtactt ggtaaaaagg gtgatgaata tatatttgca
    61561 tcagaaaatt gtgcaataga tatacttggc ggagaagtta taagagatgt agagccagga
    61621 gagataatag tagtcaaaga tggagaacta aaatcatatt tttattcaga aaattataaa
    61681 ccagttaaga aaagttgtat atttgaacac atatactttg caagaaatga tgcaactata
    61741 gacaatgtaa atgcatatga atttagaatt aaatgtggtg agagattagc tcagaatgaa
    61801 actgtaaagg cagatatggt agttccagtt ccagattcag gttggccagg agctattggt
    61861 tatgcaaatg ctagtggatt aaaaataagt gaaggcttag ttaaaaatag atatgtagga
    61921 agaacattta taaaacctac acaagaagaa agagaaatag cagtaaaaat aaaattaaat
    61981 cctctttcaa caataataaa aggaaaatct ataattttag tagacgactc aattgtaaga
    62041 ggaactacat ctaaacaatt agtaaaatct ttaagagaag caggagcaaa agaaattcat
    62101 cttagaataa cttctcctcc agtagcttac tcttgttact atggaataga tactccaaat
    62161 cgctctaaat taattgcatc aagtaacaac gtagaagaaa tgagagaata tattggatgt
    62221 gatagtttaa aattcctaga tatagaagga atgttagatg caacagaaca taagtctact
    62281 ttctgtaaag cttgttttga tggagaatac ccagttaaga aaattgataa ggaggaacta
    62341 ctttcatgtt aacatataaa gaatcaggtg tagatataga tgaaggaaat agagcagtag
    62401 accttataaa aggtaaaata aaaggaactt atgatggaaa tgtagttgga gatttaggta
    62461 acttcagtgg attatacagt ttaaaagatt ttgtaggtat gaaagaacca gttttgcttg
    62521 catctacaga tggtgttggg actaagttaa aaatagctca gatgatggac aagcatgata
    62581 ctgttggaat agatttagtt gcaatgtgcg tgaatgattt aatttgtcaa ggagcaaaac
    62641 cattattttt ccttgactat atagctcttg ggaaattagt gcctgagcat atcgaaaaaa
    62701 tagttggtgg aattgcagat ggttgtaaaa tgtctggttg tgcactaatt ggtggagaaa
    62761 ctgctgaaat gcctggaatg tatggagaag atgactatga tttagcagga ttttctgtag
    62821 gaatagcaga caaagaaaag attgtttctg gaaacaatgt taaatcagga gatgtattgg
    62881 ttggtatatc ttcaagtgga gtacacagca atggattttc ttttataaga aagatatttt
    62941 tagaaactta caattataaa atggaacaat atgttgaaga actaggaatg acagttggag
    63001 aagcactttt aacaccaact aaaatatatg ttaaattagc tttagatgta ttagctaaac
    63061 atgacataaa agctatagct cacataactg gtggagggct tatagaaaat ataacaagag
    63121 ttatacctaa agggttagga ctagatatca ataaaaaatc ttgggagaag cctcctatat
    63181 ttaaaatgat agaaggtttt aatgctgttg atgagagaga acttcataag agttttaaca
    63241 tgggtattgg gctagtttta atagtagata aagaaaatgc tgatgatgtt gtaaacttta
    63301 taaataatag agaaaatgac aatgctgctt atgtagataa aaaatacagt gaattattag
    63361 aagataaagc gtatataatt ggtgaagtag tagatagtca tgaaggtgta gaattatgct
    63421 aaatatagga gttttaatat ctggtggagg aacaaattta caagcagtta tagatggcac
    63481 tgagtctgga gaaataaaag gtcaggttaa agtagttatc tcaagtaagc aaggtgctta
    63541 tgggctagag agagctaaaa atcataacat aaaagcaatt tgtgaaactg atgaagacaa
    63601 gataatagag attcttaagg aaaataaaat agatttagta gttttggctg gttatttaaa
    63661 aataatcagc ccaaagctgg ttaatgagtt tagaaacaaa atgataaaca tacatccatc
    63721 attaattcct tcattttgtg gagctgggtt ctatggagaa aaagttcatc aaggtgttat
    63781 agattacgga gctaaagtaa ctggtgctac agttcatttt gttgatgaag gtgctgatac
    63841 tggaccaatc ataatgcaag atgtagttaa ggtaaatcaa gatgatgatg caaagacact
    63901 tgcaaaaaga gtgttagaag ttgaacatag gattttaaaa gaaagtataa gtcttttttg
    63961 tgaaaataaa ttaaaacttc aaggtaggag agtgtttata aatgagtaag agagctttaa
    64021 taagtgtaac tgacaagact ggtgtagtgg aatttgctaa ggagttaaat aagttagatt
    64081 atgaaattat atctacagga aatacattta aaacattaaa agaaaatggt gttaatgtaa
    64141 tgcaagttga agatgttaca aattttccag aaatattaga tgggagagta aaaacattaa
    64201 atccatatat acatggtggt atactttata aaagagataa agaatctcat gtagaaactg
    64261 tgaatgagca taaaatacat tcaatagatt tagtagctgt aaatctatat gattttgaag
    64321 gaactttaaa agctggaaaa agtcatgatg aaataattga aaatatagat attggtggac
    64381 catctatgat acgttctgct gccaaaaact ataaagatgt aatagtagta gtagatataa
    64441 aagattatga ttctataata gaaaaattaa aaacagatac aatgacatta gaagacagaa
    64501 aaaaattatc atataaagct ttctcaacta caggaagata tgatgcgtta atatctagtt
    64561 attttgctgg agaagttgga gatacatatc ctgacatatt aaatttaact ttccaaaaag
    64621 aacaaacttt aagatatgga gaaaatccac atcaaaatgg tttcttatat tcacaatcaa
    64681 atgcaaaaaa tccaatctta aattatgagc aattaggcgg taaagaactt tcttttaaca
    64741 atttaaatga tttacatgga tgtttagaag taatgagaga atttaaagat agtgaagaag
    64801 tagtttcagt agctataaaa catgctaatt catgtggggt aggtctagga aaagatgctt
    64861 ttgaagcata tacaaaatgt tatgaagcgg ataaggtttc aatatttgga ggaatagtag
    64921 gaataacttc tactatagat aaagctacag cagagaaatt aaatgaaata ttcttagaga
    64981 tagtagtagc atatgatttt gagccagaag ctttagaggt acttaaacaa aagaaaaatt
    65041 taagaatatt aaaattagct aagatagaag atagtttaca accatatgaa atgaaatatt
    65101 tagatggaaa attattaata caagatagaa ataatatatt agcagaaaaa agtgaaaatg
    65161 taacaaaagc aaaaccaaca gatgcacaac ttaaggacat ggaatttggt atgagagtag
    65221 taaaaaatat gaaatcaaat gcaattgcga tagtaaaaaa tggtcaaact ttagctttag
    65281 gttgtggaca aacatcaaga atttgggcat taaaaaatgc tcttgaaaat aacaaagata
    65341 aagattttac aggagctgtt ttagcgtcag atgcattttt cccatttgat gattgtgtaa
    65401 cattagctca tgaatatgga atatcagcag tagttcaacc aggtggctct ataaaggata
    65461 aagattcaat agaagcttgt gataagtatg atatggttat ggtatttaca ggaataagac
    65521 acttcaaaca ctaaggagga tattatgaag atattggttg taggcggtgg cggaagagag
    65581 catgctatat gctggaaact aagcaaagaa aaaaatgtag aaaaagttta ttgcgcgcca
    65641 ggtaatgcag gaattacaaa tgtagcagaa tgtgtaaata taggtgatac taatatagaa
    65701 gaacttttaa aatttgccaa agaaaatgaa ataggtctga caatagtagg accagaagta
    65761 ccactagtta tgggaatagt agatgagttt gaaaaagaag gattaagagt atttggacct
    65821 aataaaaaat gtgctcaact tgaaggaagt aaagcttttt caaaagaatt tatgataaaa
    65881 cataacatac ctactgcaaa atataaagaa tatacaaact tagaagaagc tatatcagaa
    65941 atagatagtt ttggatatcc agtagtaata aaagcggacg gattagctgc tggaaaaggt
    66001 gttgtaatac ctgaaaatag agaagatgct atagcaactt taaaagaaat gatgtcagat
    66061 aagaagtttg gagctgctgg agataaaata gtaattgaag agtttttaaa aggaatagaa
    66121 acttcaattc tagcatttgt agacaatgat acaatagttc ctatggcaag tgcaaaagac
    66181 cataaaaaag taaacaacta tgagcaaggt ccaaacactg ggggaatggg aactttttca
    66241 cctagtgaaa tatatacaga agaattagca aataaagtaa aagagacagt attagaaaaa
    66301 actttagaag gcttcaaaaa agatggactt aattttaaag gtattttatt tgttggtctt
    66361 atgataactg aagatggaga aaaagtactt gaatataatg taagatttgg agaccctgag
    66421 acacaatctg ttttatttag attagaaaca gatttacatg agataatgga aactatacta
    66481 gataataagt taaaagatat agaaataaac tatagtgatg atgaagctgt atgtgttatg
    66541 cttacatcag gagggtatcc agacagttat gaaaaaggga aaattataac tggtcttgaa
    66601 aacttggatg atgatatagt agtattccat agtggcacta agatgcttga tggtaattta
    66661 gttaccaatg gaggaagagt aattggtata actgcaaagt caactacagt taaggatgca
    66721 gcagaaaaag tttatgaaaa cataaagaag ataaactttg aaggaatgca ctatagaaca
    66781 gacataggaa gataattttt ctaaaatgga ggataaggta tgttgaatac tgaaaataaa
    66841 gactcaatgg ttagaagagt attagttgaa aaaagagaag gttttgacct tgaggctaaa
    66901 gctttaaaaa aagacttagt agaaagttta cacatagata atatagaaaa tttaagaata
    66961 ttaaatagat atgatgtaga aggaatatca gaagaagttt atgaaaatgc agcaaagaca
    67021 atattctctg aaccaaattt agatgtagta tattatgaag aaataccaaa attaaatgat
    67081 gaaagagtat ttgcaataga atttcttcct ggtcaatacg accaaagagg tgattgggca
    67141 gctcaatgtg tacaaattgt aaatcaaggg ataagacctg ctattaatac agcaaaagtt
    67201 tatatattat caggcaaaat aactgatgaa gagttttcta aaataaaaga ttactgtata
    67261 aatccagtag atagtagaga agcatcttta gaaaaaccag aaacattaaa aatggaaact
    67321 gaaataccaa caacagttga agtattagat ggatttatag atttagatga aaatggatta
    67381 agaacatttg taagtgaaaa aggattagca atgactttag gagacttaca acacgttcaa
    67441 aaatacttta aagatacaga aaagagaaat ccaactataa cagaaataaa agtattagat
    67501 acttattggt ctgatcattg tagacatact acttttatga ctgaaataga aaatgtaaag
    67561 atagaagatg gtaagtttaa tgatatagta aaagaagcgt atcaaatgta tcttaactca
    67621 agagacaatg tatatgtgaa cagacataaa gatatatgtt taatggatat agccactgtt
    67681 gcagtaaaag aattaaagaa gaatgggaaa ttaaatgacc tagatgaaag tgaagaaata
    67741 aatgcatgta gtataaacgt agatgttgaa gttgatggta agatggaaaa atatctagta
    67801 atgtttaaaa atgaaactca caaccatcca actgaaatag aaccatttgg tggagcagct
    67861 acttgtttag gtggagctat aagagaccca ttatcaggaa gaagttatgt ttatcaagca
    67921 atgcgtgtta caggaagtgc tgacccaaga acgactttag aagatacttt acctggaaaa
    67981 cttatgcaaa gaaaaataac tacagaagct gctcatggat atagttcata tggtaaccaa
    68041 ataggtctta caactggaca agttgcagaa gtatatgatg aaaactttgt tgcaaagaga
    68101 atggaaatag gtgcagttat agcagcagta ccaaaagaga atgtagtaag agaaagacct
    68161 gaagcaggag atgtaatagt tcttcttgga ggaaaaacag gaagagatgg ttgtggaggg
    68221 gcaactggtt catctaaaga acatagtgaa gagtcaatct taacttgtag tgcagaagtt
    68281 caaaaaggag atgctcctaa cgaaagaaaa atacaaagat tctttagaaa taaagaagtt
    68341 gctcaaatga taaaaagatg taatgatttt ggagcaggtg gagtttgtgt tgctatagga
    68401 gagattgctg atagtttaga tataaactta gacttagtac ctaaaaaata cgatggactt
    68461 gatggaactg agcttgcaat ttcagagtca caagagcgta tggcagtagc tataaaaaaa
    68521 gaaaataaag ataaatttat acaattagca gtagaagaaa acttagaagc tacacatgta
    68581 gctacagtaa cagatacagg atatttaaga atgttctgga atggaaaagc aattgtagat
    68641 ataaatagag agttcttaga tacaaacgga gtaaaacaaa ctactgatgt ccatgttact
    68701 aaagtagatg aagaaaatac attctttagc tctaatgaaa tagtaaaaga tgttaagtgt
    68761 gcaagtatga aagacaagtt tacaaaagta ttatctgacc ttaatgtttg ttctcaaaaa
    68821 ggattagtag agatgtttga taatacaatt ggtggtaata cagtacttat gccatttgga
    68881 ggaaagtatc aagcgactcc aacacaaggt atggttgcta agataccagt acttggagga
    68941 gaaactaata cttctacaat aatgacttat ggatataatc caaaggtagg aaaatggagt
    69001 ccattccatg gtgccttgta cgcagtagta gaatctgtgt gtaaattggt tgctattgga
    69061 ggaaattata gtacaacaag acttacattc caagagtatt ttgaaaaact tggtaacaat
    69121 ccagaaaaat ggggtaaacc attctcagca cttttaggag cattttatgc acaaagtaaa
    69181 tttgagatac ctgctatagg tggaaaagac agtatgtctg gtacatttaa agatatcgaa
    69241 gttccaccaa cattagtttc atttgctgtt gatacagtag atgcgaagaa agtagtatct
    69301 ccagaattta aaaaagcaga ctcaaaagta gtaatgttat gtgtaaacaa ggcagaaaat
    69361 gatgttgtag attttgagga attaaagaga aacttagaca aagtaagaga acttatacat
    69421 ggaaataaag ttttatcaac atatgcatta ggatttgcag gtgtaggtga agcaataagt
    69481 aaaatggctt ttggtaataa aataggattt aagtttagtg aagaagctga aaaaacattt
    69541 acagatgata aattatttga ggctagttat ggaaatatag tacttgaatt agcaaatgat
    69601 gatttatgta tgttagaagg atacaattat gttgtgcttg gaagtacaac taaagaagct
    69661 agtatattta tcaaaggtga agaacttgca ttagatgaat tatataaagc acactgtagt
    69721 actttagagc ctatattccc aactaaaaca gaagaagtaa aatcaaagat agagactata
    69781 agttatatat cacaaggaga agctaaaaaa tcatcattaa gtatagctac tccaagagta
    69841 tttataccag catttcctgg aacaaactgt gaatatgact ctgcaagagc atttgaaaga
    69901 gtaggagcta atgcaaacat aagagtattc aagaatttaa cttataaaga catagaagat
    69961 tctatagata caatagtaaa cgaaataaaa tcttctcaaa taataatgtt accaggtgga
    70021 tttagtgctg gtgatgagcc agatggttct ggtaaattta tagctactgt atttagaaat
    70081 cctagagtgc aagaagctat aaatgaattt ttaactcaaa aagatggact aatgttaggt
    70141 atctgtaatg gattccaagt attaattaaa ttaggattag ttccatatgg agaaataaga
    70201 gttccaagtg aaagtgctcc aacacttact tacaataata ttggtcgtca tcaagctaag
    70261 attgctagaa ctagaatttc atctaataaa tctccttggt tagctcaaac taatgttgga
    70321 gatattcata atatagcaat ttctcatgga gaaggtaaat ttgttgctag tgaagatgtt
    70381 atgagagaat taattgctaa tggacaagta gcaactcaat atgttgactt taataatgaa
    70441 gctacttatg atattgagtt taatccaaat ggttcattct atgctgttga aggtataact
    70501 agtgctgatg gtagagtgtt tggtaaaatg ggacattctg agagaattgg tgaggaagta
    70561 tttaagaata ttataggtga aaaagaccaa aagatatttg aatctggagt taaatatttt
    70621 agataaagct ttgatgttta attgatagct agaatatata atttagatat ttagatttaa
    70681 agagatgtaa taatatgatg ataatcattt aatattacat ctctttttta tttatctaag
    70741 aaataataag ttcaacctaa gttaaaatac aagctgtgtt ataattaatt actaagtaaa
    70801 attaaatatt tattggaggg caacataatt aatgaaaata ttaataacag ggtctaatgg
    70861 tcaattagga aaagaattgg ttagccaatt agaagcaatc aatcaaagta taaatcaacc
    70921 aaaatacgtt atattagcta caacaagaaa tgatttggat atatccaatc agactaatat
    70981 agataatttt attttgcata ataaacctga tgtaattgta aactgtgcag catatacaaa
    71041 ggttgatgca tgtgaagata atatcgaaat tgcgtataaa ataaatgcct taggagtgag
    71101 aaatttagca atagcatcag aaaaagttaa tgctaagctt gttcacatat caactgacta
    71161 tgtattcaat ggtttttcta aatatccata tagggaagac aataaaactg aacccaattc
    71221 tgtgtatgga aaaagtaaac ttatgggaga aaagtttgtt gaacaattct cacataagta
    71281 ctttatattg agaacagcat ggttatatgg taatgggaat aattttgtaa agactatgat
    71341 aaaactttct ttagaaaata aagaggttaa tgtggttaat gaccagtttg gaaccccaac
    71401 aagtacagta gacttagcaa aaattataat aagaatcatg gaaacagaac attatggagt
    71461 ttatcatgct acatgtgaag gtgagtgtag ttggtatgat tttgccaaaa agatatttga
    71521 attaaaaaat atagatataa aagtaaatcc aattaagagt aacgaattta aatgtaaggc
    71581 tcaaagacca ctatattctg tattggataa ttttatgttg aagttaattg gtttaaattc
    71641 ttttagaaag tgggaagaat ccattgaaga atatttagaa agatatgata taaatgaaaa
    71701 gtaaatgtat tatttttaga aaagaaaata agatattata aaaaatataa atatttcttt
    71761 tatttatccg ataatcataa tatgacaaaa acaaatttaa ggatggaaaa agatgaaagg
    71821 aattatttta gcaggagggt ctggtacaag actatatcct ataacaaaat gtatatcaaa
    71881 acaaacactt ccaatatacg ataaaccaat gatatattac cctatgtcgg ttcttatgtt
    71941 ggcagggata caagatatat taataatatc tacaccaaga gatataaaag catttgaaga
    72001 attatttgga gatggaagtt cactagggct taaaataaca tatgcaattc aggagaaagc
    72061 aaatggaatt gcagaagcgt ttataatagg agaagaattt ataggaaatg acagagtgtc
    72121 tcttgtattg ggggataata tattttatgg atatggattt agtgaaaggt tggagaatgc
    72181 agttaaaaga aaaggagcaa ctatatttgg gtatcatgta agtaatccaa attcgtttgg
    72241 agttgtagaa tttgataagg attttaatgt attatcaata gaagaaaaac ctacagttcc
    72301 taaatctaat tatgctatac caggattata tttttatgat aatgatgttg tagagatagc
    72361 aaagctagtt gaaccatcag atagaggtga attagaaata acctctataa acagtgaata
    72421 tctaaaacga ggaaaactaa aagtggaact tctaggaaga ggtatggctt ggcttgatac
    72481 tggtacacat aaaggtctat tggatgcttc taactatgtt gaagtggttc aaacaagaca
    72541 gggactgtat atagcatgtt tagaagagat tgcatataca aaaggatata taagtagaga
    72601 acaattaatg aaactagcca agccactgat aaaaactgaa tatggtcaat atctattaaa
    72661 attggctagt gaagatatgc aatatggtag ataaaattta ttataaattt tattaaggga
    72721 gtttgttata atgggaaaaa tcaatgttat aaagactaaa atagaaggat tatatatagt
    72781 cgaaccaaat gtattttgtg atgaaagagg atattttatg gaaagctata ataaaaagga
    72841 ttttatagag cagggtcttg atatgtgttt tattcaagat aatgagtcta gctcaagaaa
    72901 aggtgtttta agaggaatgc attttcaggt tagatatcct caaggaaaat tagtcagagt
    72961 tacagaggga gaagttttcg atgttgcagt tgatttaaga aaagattcac agacatttgg
    73021 gaaatgggaa ggtgtaatat tgtctgataa gaataaaaaa caattttata ttccagaagg
    73081 gtttgcacat ggatttttag ttttatcaga aaaagcagta tttaattaca aatgtacaaa
    73141 ctattattat ccagaatttg agcatgggtt tatatggaat gacaagcaaa tatctattga
    73201 gtggccttta aaaggaattg aagaaatatt tttatcagaa aaggacaaaa aacaaaaaag
    73261 ttttaaagat atttgtataa gacgttaata aaaatttatt agaattaaca tttaggagaa
    73321 aaaatatgaa aaaaatactg ataactggag gagcaggatt tattgggagt aactttgtac
    73381 attatatgct taacaagtat gtagattatt ttattgttaa cctagacttg ttgacttatg
    73441 ctggtaattt agagacatta atagaaatac aagacagttc caattataaa tttgttaaag
    73501 gagatatttc aaatagggaa cagatgtata agctatttga agaagaaagg tttgatatag
    73561 ttgttaactt tgccgctgaa tctcatgtag ataggtcagt tgagaatcct gatttattta
    73621 ttaaaacaaa cattatagga acacaagtac ttttagatgc atctataaaa tatggagtta
    73681 aaaggtatca tcaaatatct acagacgaag tgtatggtga tttaccaatt gatagaaagg
    73741 atttattctt tacagaacaa tctcctatca atccaagttc tccatattca gcttctaaag
    73801 catcagcaga tttgttggta agttcttatt atagaacata tggattgtta acaactatat
    73861 ctaggtgttc caacaattat gggccatatc attttcctga aaaattgata cctcttatga
    73921 ttttaaatgc tttggaaaac aaacaattgc cagtatatgg gaatggggaa aatgtaagag
    73981 attggttaca tgtatatgac cattgtactg ctatagactt aataatacat aaagggaata
    74041 taggggagat ttacaatata ggaggtcata atgaaagaag taatttagaa gtagtaaaaa
    74101 tgatattaaa tcttttagat aaatctgaag agttaatatc ctatgtaaat gatagacctg
    74161 gtcatgattt aagatatgct attgatgcaa ctaaaataga gaatgagtta ggttggaagg
    74221 caaaatatga ctttgatttg ggtataaaag aaactgttaa gtggtatata gaaaatgaat
    74281 cttggtggaa agctgtttta tcagtgtaac tttgaaattt ataaaattta gaaaggggcg
    74341 ttttatattg aatgagataa gttcactaat taatatatta gcattgactc aattatctgg
    74401 tagtaatact acaaatcaat gtaactgtac atataatagt tcatctggat ttgatatgat
    74461 tatgatgacc ttgttaaaag cattatcaca aaataatcaa cagacttcta atggctacaa
    74521 tttatcgtct aattctgaga atttatttga cgaactcggc agtgtagtaa ataatacagc
    74581 tagtagattt atagatgttg atacaaaaga taaaagtgta aaatcaagaa ttgaaaatgc
    74641 tatagagcaa gcatcaaaaa aatataatgt ggattcgaat cttataaaag caataattaa
    74701 agttgaatcg gattttaatc caaatactgt ttcttctgct ggtgctaagg gtcttatgca
    74761 acttatgcca gaaaattgca gagacttggg ggttacagac ccttttaata tagagcagaa
    74821 tatagatgct ggaactagac atattaagga atacattgat atgtttggag ggagcataga
    74881 aatgggattg atggcatata atggtggtcc tggaagaatg aaaagtagag gagtagaatc
    74941 aatctctgac ctgtataaaa tgccaaaaga aacacaaaat tatattccta aggttatgaa
    75001 atattataga gggtaggctt tattatgggg ataaatatag ataagctaaa cataagtcca
    75061 agtataaata tggaggttaa aaaactaaaa gagagtaata aattttctga caaattaaac
    75121 tctttaaaac aatcttcttc attggaagat ataaaacgaa atttggaaag tgtaaaaaag
    75181 gcaggagaaa ggcttgtact tactcaaaac tatggcgaca ttagtatata taaaaatgca
    75241 gtaaaagaat acctaaaatc tgttgtagat aatatgtatt cacttgataa aaatagtagc
    75301 ttttgggagc atcagtatta taagaatgta aagattgttg atagtaaact tgaggatatg
    75361 actagtaagt taattagtga agaaaaagaa aacatagata ttgtttctac tgttgatatg
    75421 atacaaggct tgttgataga tatgtataga taaggttata caaggagaaa agttttatga
    75481 atagtaaaaa agaggatata tatgaattga attttgggca attaatagaa gaaaaatctg
    75541 gtgttataga agaaaatcaa aatgttttta atgcaaaagt aaatgtagct gtttctatag
    75601 gaaatacaac agaaacaata aaaaatatat tagatttaaa agaaggctct ataataaaac
    75661 taagtaagaa tgtggatgaa aaattagata tatatgcaaa tgatagattg tttgcttatg
    75721 gagaaagcat tattacaaat gagaagttat ctgtaagatt atctaaaata gaagattcag
    75781 atgtaaatta gtattttaaa tagtatccct ttaggctatg atgtatgagt ttagctaagg
    75841 ggatattttt ataaaaaatt taaaatatgc gtgaattata taaatgtttt tattttatga
    75901 gcgataatta aattataagt atgtaatttt ggaggtgaaa ctatggatat taaaaatgta
    75961 agttcaaata ttgtagtgaa taattattta aagaatacat ctggtgtaaa aaaagtggaa
    76021 gaagttaaaa aaattaataa aacagacaag atagagctat ctaaatttgc aaaggaaatg
    76081 gcaagtgtgt caaatatgag tgatgagaat attaggaata aaaaagtcga tgaaataaaa
    76141 aatgcattag aaaatggaac ttacaaaata aaaccaaaag aaattgcgaa aaaaatgata
    76201 gaggatatgc gaggataaag tcatgattac agacttaaaa gttataatat atgaagaaaa
    76261 aaatataatt agtaagatga tggaattatt aaaagaacaa tttgattata tagttgaaaa
    76321 agacttagaa aatttaaata tgttaaatcc taaactagaa gatattagca gggagcttgc
    76381 atccatagaa ataaagagaa gacaactttt tggtgatgat atttcaatga gtgaagttgt
    76441 tgaaaatagt aatgatagat atttaaaaga aatatataca gacttgaaac acattcttgc
    76501 tttagctaaa aatcaacaag aatcaaatga ttctctaata aagaaagaac ttatttttac
    76561 gaaaaaaatg attaatttca taaaaccagc tgataagcaa actgcaactt ataattctta
    76621 tggaaatatt agaaaataaa tattaggagg agaaatatgg caggattatt ttccatttta
    76681 aatacagcta attcaggaat gaatgcgcac caaaaagcaa tacagacaat ttctcataat
    76741 ataagtaatc tagatacaga cggttattct aggcaaagga ctgagtttgc tacaaatagt
    76801 ccaatgtata tgcctagttt gagtaattca attgcaagag gacaattagg gactggagta
    76861 cacgtaacgg atgtaacaag agctagaaat agtttttatg attaccaatt tagagcagaa
    76921 gctcataagt atggtaatac agtttcaaag tatgactatt ataatactat agaaactata
    76981 ataaatgaac catcagacta tggaatatct gcaggtatag acgacttttt taaaggatgg
    77041 gaatcattag caaaggatat aaatagtgat agtaaaaaaa gtctagtggt agaaaatgca
    77101 tcaaatctag caactttaat aagtgaaagt tataagaagc ttaataagtt aaagggagat
    77161 atagacgata atataaactc tgaaataaaa cagataaatg acatgttaaa aagtcttgaa
    77221 gatttgaata aatctattga tgttatatct ggttctggct ctactccaaa tgatttactt
    77281 gatgaaagag atagaatatt agatgactta agctttaaat tagaccttga aaatagcgat
    77341 gttaaaaata tgctttcaga tggtaaatta gaacttaatg aattaaaaaa tgcagatgga
    77401 acttggaaaa caggtgtatc aggaacctta caaggcttgt ttgaaatgca tggtaagatt
    77461 gatacatata aaagcgattt aaaagatgta tctgatgggt tagctaagca gataaatgat
    77521 gtttataata catctgctgg aataacagta acagattttt ttataacttc aaatgtagat
    77581 ggtgaagata tcataaaggt aaatccagct ataaagagta acccaaatga attaaaactt
    77641 actgctgatg aggcttcaaa gattgctaag ttaaaggatg aaaaaataga tattggggtg
    77701 gctggtggaa aagtaagtac aataagtgac cactataaag cctttgcaga atcagtaggt
    77761 ttagattctc aaaaagtgaa tcaagatgaa gtgaatcaac gtaaaattat aaataatatt
    77821 gataactcac gaatgagtgt ttcaggcgta tctttggatg aagaaatgac agagcttata
    77881 aaaatacaac gctcctatca agctagtgca aaagttatgt caacagctgt gcaactgttg
    77941 gatgttgtaa taaatggaat aatttaatag aagggggaat ttataatgag agttagtaca
    78001 ggtatgatgt ctagcaacta tctaaactca ctacaagata atctacaaag attagataag
    78061 gttaatagac aagttaatac aacgaaagaa ataaacaagc tatcagataa tccatataag
    78121 gcaataaaaa tattgaactc aaaaagtgaa ataaaaacta tggagactta tgttgagaat
    78181 tgtaaagata cagggaattg gttagaaact actgatactg cattagatca gcttggaaaa
    78241 ttattatcgg acataaagaa aactttggtg gcaagtggtg atggtgcata ttcagatgat
    78301 gagctaaaga ctcttagtaa tgaaactaat gaaaagatga aagaaattgc aaatgcctta
    78361 aatgcaacac atgaaggaaa gtacatattt tcaggttcaa atacaggtgt accacctgtt
    78421 gaatgtatag ataatgctga cggttcagtg agcttaaagt ttaattctag tttaaatctt
    78481 aataaattaa atgactcttt gagtatggat atagctcaag gaataagtgt agattataat
    78541 gttaaattga gtagccttgg atttgaccca acaaagactg acccatttga agagttaaat
    78601 aatatatcaa agaaattagc aaatccagat gctgatgcta taaaagagct gacaacaact
    78661 tgtttaggcg acatggaaca attaatagaa aatacagtaa atgttaggtc tatatatggg
    78721 acaaaagcaa atacagtaga ggctatgaag gaaaaaaatg atgatagttt gatacagtta
    78781 aaggatattt tgtcacaaaa tgaagaaata gattatggag aaaaactcgt tcaattaaag
    78841 gcagcagagt taacttatca agcttcacta caaacaggag gaaagttatt taatgtatct
    78901 atattagatt acatatagta aaataacgca gatatgatga aggttacatt aaaaaaaggt
    78961 atattaggtt ttgaaaattt aaaagaatat gagcttttag atatagaaga taatgattct
    79021 ttaaaagaat ttaattctac tgaagaagaa ggtataggat ttgttgttgt atctccattt
    79081 gagattatca atgaatatga aatagtttta aatcaggaaa caatagaaaa actagaagtg
    79141 aaatctccaa aggatgttgt actatttaat ataattactc ttggtcagac atttgaagaa
    79201 tcaactgtga acatgaaagc tcctatagtg ataaatataa aaactaattt tggaatgcaa
    79261 ataattttac aggatgataa atattcaata aggcatccat tattgagagg tgataatgga
    79321 tgctagtaat ttcaagaaaa aaagatgaag cagtacttat aggagaaagc atagaagtaa
    79381 aaattgtagg ggtagatgga aacaatgtga aactagctat atcggcgcct aacaatataa
    79441 gtatattaag aaaagaaata tacgaaaaag taaagagtga gaatataaaa gctacaaata
    79501 aaaatataaa aattttaaag tcattaaaat aataagcttg gaggaagtaa tatatgtatg
    79561 gagaaaatcc ttataattct tataaacaaa atgctgtttt tatggcatca aaggaacaat
    79621 tgttacttat gcttgttgat ggagcagtaa aatataccaa aatagccaga gcagctatct
    79681 tagataaaaa tacacagaaa gcgcatagag aacttgtaag agttcaggat atatttacag
    79741 aactaatggt tacattagac caaaatgcag gacaatgggc aaaggatatg tacaaagttt
    79801 atgattttgt aagatatgaa ctttcaagag ccaatattag aaaagacatc caggtaatag
    79861 ataatgtgtt gcctgtaata gaacaaatta aagacacatg gcatgaagct gataaaaaaa
    79921 gtaaagaaga aagaagtagg tacaaataat ggaattaaat ttagctgaat tagataagtt
    79981 atcaaaagag gaattactat tgatgcttgt agatggcaca gtaaaatata ccaatatatc
    80041 caaagaagct cttttaaata acgactattt gaaagcacat aatgaactta taagagttca
    80101 aaatatattt acagaactaa tgactacatt agaccaagat gcaggtcaat gggcaaagga
    80161 tatgtataaa gtttatgaat ttataaaatc tgaattagca atagctgatg aaaataaaga
    80221 tattaaaata attgatgata tattgccaat agtaaaacaa attagagata catggcatga
    80281 agtttacaat caactaaaaa tataattaga tggagggata aaggtatgtc aagtataagt
    80341 cctataagag ttacaggtct ttcaggaaat tttgatatgg aaggcataat cgaagctagt
    80401 atgattagag acaaggaaaa agttgataaa gcaaaacaag aacaacaaat cgttaaatgg
    80461 aagcaagaaa tatatagaaa tgttatacaa gaatcaaaag atctttatga taaatatcta
    80521 agcgtaaatt ctcctaatag tatagtaagt gaaaaagcat actcttctac aagaataacc
    80581 agttctgatg aaagtattat agtagcaaaa ggctcagctg gtgcagaaaa aataaattat
    80641 caatttgcag tttctcaaat ggctgaacca gcaaaattta ctattaaatt aaattcaagt
    80701 gaacctattg ttcgacagtt ccctccaaat gccagtggag ctagttcttt aactatagga
    80761 gatgtaaata taccaatatc tgaacaagat actacaagta ctattgtaag taagataaac
    80821 tccctttgcg cagataatga tataaaggct tcttatagtg agatgacagg tgaattgatt
    80881 atttcgagaa aacaaactgg ttcgtcatca gacattaatt taaaagtaat tggaaatgac
    80941 aatttagctc agcaaattgc taatgataat ggtatcacat ttgcaaatga tgctagtgga
    81001 aacaaagtgg caagtgtata tggaaaaaat ctagaagctg atgtaactga tgaacatgga
    81061 agagtaactc atataagtaa agaacaaaat tcatttaata tagataatat tgactataat
    81121 gtaaattcaa aaggaactgc aaagttgact tctgtcactg atactgaaga agctgttaaa
    81181 aatatgcaag catttgtgga tgattataat aaactgatgg acaaggtcta tggtttagtt
    81241 actactaaaa aaccaaaaga ttatccgcct cttacagatg cccaaaaaga agatatgaca
    81301 actgaagaaa tagaaaaatg ggaaaagaaa gctaaagaag gtatacttag aaatgatgat
    81361 gagttaagag gttttgttga agatattcag tctgcatttt ttggagatgg aaaaaatatt
    81421 attgcattaa gaaaactagg tatcaatgaa agcgaaaatt acaataaaaa aggtcaaata
    81481 tcatttaatg cagatacttt ttcaaaggct cttatagatg atagtgataa ggtatacaaa
    81541 acactagcag gttattcttc gaattatgat gataagggaa tgtttgaaaa gctaaaagat
    81601 attgtatatg aatattctgg aagttcaact tctaaacttc ctaaaaaagc aggtatagaa
    81661 aaaactgctt ctgctagtga aaatgtatat tcaaaacaaa ttgcagagca agaaagaaat
    81721 ataagcaggt tagttgaaaa aatgaatgat aaagagaaaa gactttatgc taaatattca
    81781 gccttagaat ctttgttgaa tcagtattct tcccaaatga attatttctc acaagcacag
    81841 ggtaattaat tatggataaa ttaaaagaaa aattaaattt atataaagat atatctttac
    81901 aaattataaa tttgattgaa aaggaagaat atataaagat aagtagtaag ttaggtgaaa
    81961 gacaagagat tataaatagt gtaagtgaaa ttgatagaaa tgattttata cagctttata
    82021 atagaatgga attaattgaa attgatagta ggataagaga tattttacaa ggacaattat
    82081 tagaagtaaa aaaagaatta catgagtata agcttactaa acaagtgaac acaatgtatt
    82141 ataacttaaa tagagaaaaa gtaaatattt ttaataaaaa agtataaagt tatgtaccat
    82201 cttgtccgat tatataaatg aagaattaat aaaaaagatt aaaagtagaa atgacaagga
    82261 tgtcaactat actaaggagg gtaaaataat gagagttaat acaaatgtaa gtgctttgat
    82321 agcaaataac caaatgggaa gaaacgtaaa tgcacaaagt aagtctatgg agaagttatc
    82381 ttctggtgtt agaattaaga gagctgctga tgatgctgct gggcttgcta tatctgagaa
    82441 aatgagagct caaataaaag gtttagacca agcaggaaga aacgttcaag atggtatatc
    82501 tgttgtacaa acagcagaag gtgcattaga agaaactggt aatatactac aaagaatgag
    82561 aactttatca gtacaatctt caaatgaaac taatactgct gaagaaagac aaaagatagc
    82621 tgatgagttg ttacaattaa aggatgaagt tgaaagaata tcaagctcaa ttgagtttaa
    82681 tggtaagaaa ttacttgatg gaagttctac agaaataaga ttacaagttg gagctaattt
    82741 tggaacaaat gttgcaggaa caactaacaa caacaatgaa ataaaagttg ctctagtaaa
    82801 tacttcaagt ataatgagta aagcaggtat aacaagttct acaatagcaa gcttaaatgc
    82861 agatggaact tctggaacag atgcagctaa acaaatggtg tctagcttag atgtagctct
    82921 taaagaatta aatacatcaa gagcaaaatt aggggcacaa caaaatagac tagaatcaac
    82981 tcaaaacaac ttaaataata ctatagaaaa tgttacagca gctgaatcaa gaataagaga
    83041 tacagatgtt gcttcagaaa tggttaactt atctaaaatg aatatattag ttcaagcatc
    83101 acagtcaatg cttgctcaag ctaatcagca accacaagga gttttacaat tattaggata
    83161 aaataatttt gtatattgga tatagaagaa agggtaaggc tttgctttac tcctttcttt
    83221 ttttacaaat atacttttga aaggaaaata tatatgttac ttagtatagt tatgattgtt
    83281 aaaaatgaag aaaaaatact tgaaaaaact ttaaaatcat taaccacatt aagaagttct
    83341 atagagagtg aacttataat agttgataca ggttctacag atgatactat aaatatatct
    83401 aggaaataca cggaaaatgt gtactttcat aattggaata atgatttttc tagtatgaga
    83461 aatatatcaa tatcctatgc taaaggtgaa tggttactta tattagatgc agatgaaata
    83521 ctaattgatt cttcaactat tgtgaaattt tttaaagatg gtcttgataa aaaatttaat
    83581 tcggcctcaa tacaattaaa aaatctttac tcatatgata aaaaattata tggatattgc
    83641 tcagtgctta gactttttaa aaacatcgat tttagatacc atggtaaagt acatgaacaa
    83701 ccaatataca aaaaccctat atttaataat gttgctgatt ttgaacatta tggatatttg
    83761 tttgaagatg aagaaataag attaaataaa gtaaaaagaa atgaaaaact gttatttgaa
    83821 gaattaaaag agaatgataa ttctccatat acaaattatc aattagggaa aaattttatt
    83881 atattaggaa aatatcatga ggctttatac tatcttgaga aatcttatga attatattct
    83941 aaactagaat cggcacctgg ttacttgata acaagtcttg taaaaacata tttatattta
    84001 ggaaagcata agaagtgtga aaaattgtgt ctaaagtata ttaagaaaga catgaataat
    84061 attgatatat attattatat tgcacaagca caagtagatt tagggaagta tgaaaatagt
    84121 atagattcgt ataagagata tatttatttg ttagataatt atgaaataag tacacaagca
    84181 aatagtttat tttcagacac tgatactgta gggcttaggg atgaagctat tattacactg
    84241 ataaagattt attataaact tgaaaaatat gagtctgtaa tttcagagta caataacatt
    84301 gaggatatgg aaaagaagaa gaatgtgtac tttagcttat ttatgtccct atacaaattg
    84361 aacagatttg aagatataaa aaactattat aaagaagttt caaattctaa aattgaaaaa
    84421 aatagttttt ataaaaatat agaagaagtt ataaataata ttaaagatga tgaaaaagag
    84481 catgtatata aaatcctttg tgacattgaa ggtaattatg gcattttaaa tcagataagg
    84541 ataaataaat gtgtatctat agataagtgt aaagaaatac tcaatgaaga aaaagaaata
    84601 atttatgcat atattataaa agtagctttt gaagataaga ttgatttact agatattttt
    84661 tatgaaatgg aatatgtatg gatagagaaa tacctaaaat atcttttagc actagaaaga
    84721 agttttaatt tagtactata taagtacata attagtcgtc cgaatacatc agatataaaa
    84781 aagataagag tatataaagc tatatctaaa gtagttttag aaagtataag tttaagtgat
    84841 gaaaaatata aggagatttt ttatctttat ataatgtatt cttataagta cataagatac
    84901 atatatagaa atttaagcga ttttgaatta ataaaatttg tttgcaatga tttagataag
    84961 tttactatag aatttaagca tctacttgac attaaaaata aagtaaatga tgctaatgaa
    85021 aaattagagt atatacatag tatgaggaaa ttactaaatg agtatccttt ttataataaa
    85081 ataataaaaa tacttataag tgaattagaa gaaaatataa aagaaagtga agaatttaag
    85141 gatttaaaag atagttttat tattagtata gaaaatatga ttgaaactgg caaaataaat
    85201 gatgcgaaat cattggtaga tgactattca aaaacattta tggatgatgt aaaaatttta
    85261 aatataaagg gaattttata tatgtttgaa aataagcttg ataaagctga ttttatgtta
    85321 aaaaaggcat tatcattaga tgtagaaaat gaagatacta tatataatat agaatactta
    85381 aaaagtttaa gataagtcaa aaatgggaga attgaagaat gaatacacca atagtggtta
    85441 atgaaaaatc taaagatata ataaaagatt ggcaatatac gtatacaaac gaagatataa
    85501 aatttacaag cataataata ttgacatata atcaaataga atatactaaa ttatgtattg
    85561 aaagtattag gaagtttacc ccaaagaata aatatgaaat aataataatt gacaataact
    85621 cttctgatgg aacagttgag tggttaaagg gacaatctga cataaaatct gtatataata
    85681 acaaaaacct aggatttcca aaaggatgca atcaaggtat tgagttggct actggtgaaa
    85741 acatattgtt gttaaataat gatgtaatag ttactccaaa ttggctttat aatttgaata
    85801 aagctttatg gtctcaagat aatataggtg ctgtaggtcc tattacaaat gcatgttcgt
    85861 actatcaaca aattgatgtt gattataaat caattgagga tatgtttatg tttgcacaca
    85921 aaataaatac atctaatatt aacctatgga aatatagatt aaagttagtt ggattttgca
    85981 tgttaataaa aaaatctgtg ctggataatg taggggtttt agatgaatta ttcacacctg
    86041 gaaattttga agatgatgat ttatctttta ggatgctaga gtcaggatat aagctattat
    86101 tatgccagga tacttttata caccattttg gaagtgtatc ttttaaagaa aatcgtaata
    86161 aatatacaga tataatgtat attaatagaa gaaaatttga aactaagtgg ggatttaatc
    86221 cagaatatag tggaatgata agaacagatt tgatttctaa aatagatgat agtttggagg
    86281 caaatattaa tgttttagaa ataggctgtg gtataggggc tactctttta gaaataaaaa
    86341 atatatataa aaatgcatca atatatggaa tagaaattag tgagtcagca ggtaaacttg
    86401 caaagtatag tgcagatgta cttatagcag atatagaaaa agtaaagttg gattatgaaa
    86461 aagatttttt tgattatata atattgggag atgtacttga acatttaact gacccatgga
    86521 agatagtcaa tgaactgaaa caatatctaa agaaggatgg ttgtttgata tctagtatac
    86581 caaatattat gcatgtttct gttttaagaa accttgtgtt aggtaatttt acatatgaag
    86641 attcaggaat tttagacaag actcatttaa ggttttttac attaaatgag ataacaaaaa
    86701 tgtttaatga tagtaattac ataataaata gtgttacagc tactagtatg ccactttcgg
    86761 aaattgataa tagattcatt gatacaatgt gtaaggaaag ctgtaaagaa atgagacaac
    86821 agtacgaatc ttatcaatat atagtaaaag ccactaaaag catagatact aaaagatatt
    86881 ctagtattag tatggttaat ttaaaatacg ctttaatgag aattgataat gaattagatg
    86941 tagatagtaa tttaagttat atatttgata attataatat aactgaacca tgttttgttg
    87001 atgatattga atatttagtt gatacgtttg tgataaataa agcaactcta ttaaatagat
    87061 taggagttga ggcatttaac agaggtttag gagattttag tataaacatg tttatgacag
    87121 tattagagat ggatagagat gatattgatt caatatataa tataacaagt gtattatgtg
    87181 aattagaaga atttgatact gcttacaact taattaaaaa tagtagcaaa aaagtacaga
    87241 gtgaaagtga catacaagat atactttatt ttattgaggg gaagagatat gaataatgat
    87301 aagatatgtt ttataacctg tgtaaatgat gaaagacttt atgaggaatg tcttgtatat
    87361 ataaatagcc tagacattcc taaaaacttt agcatagaaa cagtagcttt aagaggagcc
    87421 gattctattg cctctgctta taataaagct atgagagaaa cagattctaa gtataaggta
    87481 tacttacatc aagatgcttt tataattaat aaaaatttca tatatgacat tttagagata
    87541 tttaaaaaaa atacagatgt aggaatgatt ggtgtagctg gagtaaaaga tatacctgtg
    87601 aatggaattt ggtgggattc tgataaaaaa gcagggaaag tatatgatag ccatacaggt
    87661 aaaatggata tttatgaatt tagtaacttt gaagaatgtt ttaatgaagt tatggctata
    87721 gatggattaa ttatgattac tcaatatgat gtattttgga gagaggataa gtttgatggg
    87781 tggcattttt atgatttgtc acagagtatg gaatttagac aaaataaata caaagttatt
    87841 gtaccaaaac aaaataagcc ttggtgtatg catgattctg gagtagcaaa tataaataat
    87901 ggatatgatg aatataggat aaaatttgta aaagagtaca taaatcttga tttatataga
    87961 gaaaattttt atgaatttga taagaagaaa gcaagtacca tacttaagag taataagcat
    88021 gtaatggatt gtatgaaaga ggagcttaca gaacaattaa gattaaagaa ttataaggat
    88081 gttttagata ttgtttctaa aattgctcat ttttctgttt ttaatcatac tggcttgtat
    88141 tcttgtgaaa aatgtgagag agcattgcta gaatgtgcaa ataatttacc agaaatagaa
    88201 aatacgaaat tatttacaaa aaaagattta aaaagaagaa aagtattaca tgttttaagt
    88261 gaaggatatt caacaggagg gcatacaaga ctagttaaaa attggattga gattgacaaa
    88321 gattctgttc attcagttgt aactacatgg caatcagata cactgccaga ctggttatta
    88381 aaagcaatag atgatagtgg tggcgaagtt atatctttgg atttaatttc agatgattat
    88441 ttaaaaagag ctgtagcttt gaggaaaata gcttatgact gggctgatat agttatttta
    88501 tatgttcata tgtgggatac aatacctgtt gttgcttttg gagttgatgg gaaaatacct
    88561 attttacatg ttaatcacta tgatagtact ttttggttag ggacaagtat tgcagatatt
    88621 gtcattgatt ttagcgaagc tagtcaatta attacattag ataaaagagg catagataaa
    88681 tctgaaatat taccaatgcc attaaaagaa aaagaagtat tttcaaaatc tgaagttaga
    88741 aaacgatata atttggagga tgatgtgaca ataatattga ctattgctag tgaaagaaaa
    88801 tacaatagtg taaatgatat taattacttt aaaattgcta aaacattgat tgaaaataca
    88861 gataatacaa ttattattgt tgtaggagtt gatacagaga atctctattg gaaaacttta
    88921 agtaacgtta cagataatag agttatatgt tttggaacaa cagcaaatat agacgatttt
    88981 tataagattt cggatatata cctagagtct ttcatggtag ggagtcatac ttcaaaatta
    89041 gatgcaattt tatatgattt aattcctgtt aagtttaaaa atgaagtttc accaattttt
    89101 acaaatatgt ggaattttat agataagttt gattataaga atataaaaga ggttatagac
    89161 atgataagaa ggtacaatac tagtgaattt gacagggata agataaaaga aaaacaatca
    89221 gaaataaaac attttgttat agataaacac tgtattgaaa taaaaaacta tatagacaaa
    89281 atatataaag aggctaatca tcataaagtt aagtatgatt tatataaaaa tgatgaaatc
    89341 gaagactatc agctttttgt tgcattatat ggttatatgg taaaaaataa aaacatgtca
    89401 taggtgataa aatgaacaat attcatatca ataaatttga aaaaagctgt gaaaaaaact
    89461 gggattattt tgtagaaaat aaatctataa atggtacatt tctgcaaact agaaatttcc
    89521 ttaattatca tgaagaagga aaattcactg accactcatt aataatatat aaaggtgaag
    89581 aaatactagc agtcgtacct gcatgtgaaa cttatgaaaa tggtgaaaga gtattttttt
    89641 ctcatttagg aagcactttt ggaggtatta taataagaag tggttttaat gatattaggc
    89701 atgtaaatgc tattacaaat aagttagaaa catatttaca ggaacaaagt ttcaataaag
    89761 tatatttaaa aaatacatca agaatatttt gtaaagagga tacttcatta ctagaatatt
    89821 ttctatttaa gaataattac atgttttatg atgaattaag tatgttttta gaattaagta
    89881 agtataaaaa agatatatta gctaatttta gatatagtaa aagaagatat tttaaatatt
    89941 ctttgaagaa taatcttacc tttaaaagat tgtatagtga tgaggatata gtttgttttt
    90001 ttaatttact ttctaattgt ttagatagta aaggagctaa agtaatacat tcagtagaag
    90061 aacttttgga gtttaaaaat aatagattaa aagatattgt agaattttat gcagtatata
    90121 ttgatgacat tatgatttgt gggagcatgg tatttaactt tcaagaaaga gtttatcata
    90181 ctcaatatct agcatcaaat tcgacatata ataaatatta tccaatgata tttttatact
    90241 ataatctaat aaaagatgct ttagagagaa attttaagta tctttctttt ggaattagca
    90301 ctctaaatag aggcaaatac ttagacgagg gtttagctac atttaaagaa ggttttggtt
    90361 caagtgcaat ttgcaacaga acatactata aaaatataaa taagtgataa tcatgtttta
    90421 tagagttttt agagtatagt aaatatctag tactctaata ttacataaaa ataattagtt
    90481 tataaagaag gtttgtatat gaaaagatta atgattttag gctcaattaa gtattttgag
    90541 aatattgtta tgtcagctaa aaaagaggga atatacacaa ttgtttgtga taatagaatt
    90601 gatactcctg cgaaaaagat ttgtgatgaa gcaatagatg ttgatgtatt tgattttgat
    90661 aaaataaaaa gtatagctat agataaaaag atagatggaa ttttaactgg atttacagat
    90721 tctttaatga aaccatatgt ttatattgca aatgaactaa atttaccatg tgtgatttct
    90781 tgcaatcaac ttgaatctgt aactaataag gctattatga aaaaatattt taaaaataat
    90841 gcaataccta caactgatta ttgtattatt gaaagtctaa aagatttaga aaaaatacaa
    90901 ggattaaatt ttccacttgt aataaaacct gttgatggtt atggttcaag aggtgtatat
    90961 tttgtatcaa atatagaaga attaatagaa aaatttgaat attctaagga agcctcacaa
    91021 gatggacaag taataattga ggaattttat gaaagtgagg aaatacaagg actagcttgg
    91081 gttcataatg gagagtcaca tgtattttat attggagata gagagcttgt aaatatacat
    91141 acaggaagag ctggaaaacc agatagatta ctttatccat caaagtattg ttttcaatat
    91201 gaggaagaaa taaaatctat atatcaaaat ataacacagg cttttgatat aaaaaatgga
    91261 cctctttatg tacaaatgtt agtgggagca tatggaataa aggtatctga agtaatgcca
    91321 agattacctg gaggttgtga ctatatggct atttctcaaa taacagattt agacatagga
    91381 agtttatttg caaactttag tgtgaataat gaagtaaatt ttgatgaaat aaagaaatat
    91441 aatatgcatt tatcaaaatg tgtatatgca ttaccaatat acataagacc tggaacaata
    91501 aaaaagataa ataatataga taaaatagaa aacttagatt atgtcactca atttctatta
    91561 ttagtaaaag aaggagatac aataggatta tatgaggatg agagacagga ttgtggaaga
    91621 gtttatggaa tagcaaataa tatatttgat gcaaatataa agaagaaatg tattcatgaa
    91681 atgatagaaa tatttgatga aaataatgaa aatatgatag aaaattttta aataagggag
    91741 tatgatagat atgaagctaa taactcatga acaaattatg tcattaaaca tttctcagaa
    91801 acaaggatat gaatggataa aagaatcttt tttaacaaaa aaagattgtc aattaccacc
    91861 aaaaataagc atggtagaag aaggtcatgt attttacaat gtaatgccgt ccttaaatca
    91921 taaccatatg attggtggaa taaaaatggt tacaagattg ccagggagaa atccaagttt
    91981 aaattcagat atatttctat acaatatgaa agatgctaaa ttaaaggcta ttttggatgg
    92041 taattatatt acagctttta gaactgctgc tgttgctggt ttggctattg atacttttgc
    92101 taaaaaagat tttaatacta tttctattat gggtttaggt gtaactgctt ctgctataat
    92161 gaatatgctt tcgtatactc ttaaagataa aaatataaat ataaagttac ttaaatataa
    92221 agaccaagca gagtcattta taaaaaagta tgaaaaaaat gaacaattta gttttgaaat
    92281 atgtgataca catgaagaac ttattgtaga ttcagatgta gttatttcta ctgtgacata
    92341 tacagatgaa tatttatcag aatttaaatg gtttaaaaaa ggtgctttat tattacctgt
    92401 acatgttatg ggatttggaa atgttgatta tctatttgat aaagtatatt tagatgatta
    92461 taatcatttg aaacatctag aaaatataga tagatataaa tattcttgtg aattttataa
    92521 tgttttaagt aaacaagcta aaggaagaga aaatgatgat gagagaataa tatcttacaa
    92581 tataggtttg tcaatacatg atatattatt tgcaaacaaa atttacgaat tgtgtgaaac
    92641 actaaattgt gaagagatag aattaaaaga accaaaagaa aaatattgga tatagtttat
    92701 ttcattcata tttacaataa tttattgtaa atatgaatat gaagtaatat attgttagaa
    92761 aattagcatg aataggatag ataaatttat ggataaatat aatttaatta agttcttatc
    92821 tattggaaac gaatatatag gaaatttagt tgcattagaa tcaaataaag caataccttt
    92881 tgatataaag agagtttatt acatatatga tgtaccaaac aatgtaaaga gaggatttca
    92941 tgcacacaaa aacttggaac aagtactagt ttgcctaaat ggaagtgtga agataaaatg
    93001 ttatgatggt gtaaaagaga gtatatttaa tttacataaa aatgatgttg gattgtatat
    93061 aggaacggga gtgtggcatg agatgtttga ctttgatgaa aaaactgttt taatttctat
    93121 agcatctgaa cattacaatg aagaagatta tattagagac tataaagaat ttttaaagta
    93181 tttaaataat atgtagttat tatacagtta gtgatgtatt ttcttaatta aataaattta
    93241 agatagccat atagagaata aatagattag gatgtgaatt tattgttggt taaatttaat
    93301 aatttattaa aacagttcca aactcataaa gaagaatatg aacagaagat taaggatgta
    93361 atggaaagtg gatattatat ccttggaaat gaagtaaggc attttgaaga agaatttgct
    93421 agctatgtag gtagcaaata ttgtgttggt ttagccagtg gtttagatgc acttataatt
    93481 gcttttagag cattaggaat aagtgaaggt gatgaagtaa tcgtgcaatc aaatacatat
    93541 attgctagtg ttatgggaat cagcataaat ggagcaacac cagtatttgt agaaccaaat
    93601 gaatattata atatagattc atctaagata gaagaaaaga taaatagcaa aacaaaagct
    93661 atattagtag ttcatttata tggtcaagca agtaaaatga aagatataca agaattatgt
    93721 gataagtata acttgtattt aattgaagat tgtgctcaat ctcatggagc taaatatgat
    93781 ggaaaaatga caggaacatt tggtgatata ggttgtttta gtttttatcc aagtaaaaat
    93841 ttgggtgcat ttggagatgc aggagctata gtaactagta atgaggaaat agctgataaa
    93901 gtgaaaattc ttagaaacta tggttcagaa aagcgatatt ataataaatt tgtcggatat
    93961 aattcaagat tggacgaaat tcaggcaggt ttattaagag taaaacttaa atatctaaat
    94021 gaaattgaaa ttgaaaaatc aaaaatcgta gatagatatc ttaatgaaat taataatccc
    94081 aaagtcatac ttccaaagat agaaaataat tgtactcatg tatggcactt atttgtttta
    94141 caagttgaaa aacgagatac atttatggaa tacttaaaga aaaatggtat agagtctata
    94201 atacattatc cgataccacc acatctatct gaagcatatg cttatttggg atataaaaag
    94261 gggagtttta atatagctga gaactattca gataaagttg ttagtatacc tttatttgtc
    94321 ggtatggaag atgaagaagt tagttatata attaaaatta taaatgaata ttaaactaat
    94381 cataataata tcaaaaataa attttctata tatcatttat ttaaatttcg ttaattgaca
    94441 tttttaaata ttgatatatt gtacaaataa aattgaaata tatggaagaa tatagaataa
    94501 agatgagatt tgtctaatat ttttataaat taaaaatatt ttcaaagagt ttattataaa
    94561 attgtagact atagtgttta taatctttgt aattattggt aactaaattt aaaaaataaa
    94621 atatttaatt atacacaaaa aagatattta aaaaatttgt tatttattgt atacttaagt
    94681 taaaactaaa taggcaaatc tagagaaatc tagtgacgca aagctatagg ggctaaggtt
    94741 tgtatacaca aactatgtca gccagttgcc aaaaagagtt ctaggtatat tgtatacgta
    94801 ggaagagtct aggatgactg cctttttggt ggtcattttg ttatggaaaa aatcacatta
    94861 tgtagtaaaa aacacctata ataacatatt ataccaaata taatttaaaa taaagataaa
    94921 ttatctataa aagttactat tttacaaaaa aaggcaactt tataaagaaa tatttaaatt
    94981 tatattaaaa tatttttata tttttattag gatttacgaa aataatatta gttttcttac
    95041 caaagtgata cattattata ttaatgtaat agaaatgtaa ttaatttgga tgaataaaga
    95101 agtcattttt tgtaatatag caacttcatt ttttattaat aagcaaaata aataaaatat
    95161 attttgagga ggagtgagtg tgaatacata tgacattata aaaatgggat tagatgcaac
    95221 taatttaaga agtcagacaa tagcaaataa tatagccaat ataaatactg aaggatataa
    95281 gagacattat gtaacttttg aagaaacatt aaatgatgct atgccaaaaa tagaagaaaa
    95341 aacagacaat tctaaaggat taagagtgga tggcaataat gtagatatag aagaagaaaa
    95401 agtaaatcaa gcaatggcaa cattacaata taatgctttg ataagttttg caaatggaaa
    95461 aatagcaatg actaaatcaa taataagtgg gaggtaatta aaaggtgagt gtgttcagtg
    95521 gaatgagaat atctgctagt ggattaacag cagaaagctt gaaaatggat atcatatcgt
    95581 ccaatgtagc taatataaat gccacaagag gtccaaatgg agaagcatat aggagaaaag
    95641 ttgtttcatt tgaagaaaac tatgataata aattaggtat gctaggagta aaagttacat
    95701 ctgttgaaga tgataaatca cctcttaaag aagtatatga cccatctcat ccagatgcaa
    95761 agccaaatgg atatgtagaa tatccaaatg taaatatatt ggtagaaatg acagatttaa
    95821 taacagcttc acgagcatat gattctaacg tagatacatt gaatgctcag aagtctatga
    95881 tatcaaaagc tttggaaata ggaaagtagg gataaattat gccaattaca caaattaaca
    95941 atttaatgca aggtgcaaag ttagataatt tgattggaga aacaaaacca ttaactctta
    96001 ataataaaga agaaaaaaag aactttgaag atgtaataat agatactata gataaagtta
    96061 attttcaaca agtgacagca gatgatatga aagaaaaatt tataaaaggc gaagatgttt
    96121 ctatgcatga agttatgtta ataggtcaag aagcacagct atctatgcaa tatttaatag
    96181 aagttagaaa taagattcat gatgcatatc aagaaatgaa taaggtacaa atttagcctt
    96241 ttgaacagga gtaataatca atgatagcca gttttaaaaa taagattaaa gagcaagttg
    96301 ctaaatctag gacaaagata agttctctaa aaaagggaac taaaatagca ttaggtatag
    96361 gggttattgc tatatgttta gcgctagtat ttacagcaat atctgcgagc aaaaataagt
    96421 atgcagtctt attttcagaa ctagatgttc aagatgctgc agatatatca gcagaattag
    96481 agtctaaaaa gatagatact aaggtaaagg gaagtacgat ttatgtacct agaacagaag
    96541 ttgataagtt aaggctggag ctagcaccaa gtcttacagg tggttctaaa ggatttgcac
    96601 taatggatga tagttcatca ataggactta ctgatgaaga gtttcagatt aagaagcaaa
    96661 gaatgataca aggtgaaata gaaaaaacaa taaagagttt tccacaagtg gaagatacta
    96721 gagtacatat aacatttgga gagtcatcag tatttgagaa ggaggctatt ccagggagtg
    96781 cagcagttta tttgatgtta aaaccaggga cgactttgga aaaaaaccaa ataaaatctg
    96841 ttatggcact tatatcagga agtgttacaa atataccaga gaaaaatgtt caagtcattg
    96901 ataacaaaat gaatttatta tctgaaggta ttttagagga tgaagatgtt gatgaaaata
    96961 atcaaccaac aaatagtttg attaatgttg ataaaaataa ggcatctgaa caagcattga
    97021 ataaacaatt agaaaagtct attttagaaa tgctagaacc aatatttggt aaaggaaaag
    97081 taaaagccac agtaaatgct gatttaagtt ttgatacagc tgaaaaaact gagataaaaa
    97141 ttgaccctga taaagttgca ataaaggaga caaggtcgaa aaattcatct aaatctgcta
    97201 caaataatgt tcaaggtgta gatgctaaca tgaataacca aggaaataac aatggtacta
    97261 atacagaaga tagtttagat gagagttttg agtatgaaac aggtaagatt gaaactcaca
    97321 ctatagttgc gcctggagaa cttaatagat tgacagcttc tgttgcaata gatggaaaaa
    97381 tagctaaagg tgtacaagct gatgtagagg atattgttaa taatgctata ggtatggatg
    97441 gagcgagggg agatactctt agcgttgttt caatggtatt tgacccagaa gggaaggcag
    97501 aagctaaaca agagctagaa gagattaaaa aagaaggatt taaaaagaac ataataaaag
    97561 cagttattgg agtagtggca gtggtagcaa ttggagctat tggatactta atatataaga
    97621 aaagaagtga acgagaagat atggattatg aagatgaaga ttatatttct aaatctgatt
    97681 ctgttgatag gaaggataat cctctattag gagatgaccc agaactgaca ttagaggaag
    97741 ctgttaaaat gtatgcagaa gaaaagccag accaagtaac agagataata aaaacttggt
    97801 taaatgagta agggggatag aaagtgtcca cggaaattac aaatgttaat gcgtttgact
    97861 taagtgatat aaatgaaagt gataagaaag agaagataga aggtgagggt ttaaaaaaag
    97921 ctgctgtatt attaatgaca ttaggaccaa atgtgtctag tgatataata aaaagcttgc
    97981 ctgataaaca agttcaaaaa ataggtttag aaattgcaaa tatttcttca atagcttcaa
    98041 aagaaagaag agaaatctta aaagagtttg tagagataaa tagggcaaaa gattatgtta
    98101 tagaaggtgg gcttgaatat gcaagagagt tgttaagcaa tgctttagga aatgctaaag
    98161 caaacaaatt acttgaaggt atatcaataa atacaagtac aaagcctttt aaacatatta
    98221 taaaactaga tgtaaagaaa atattagaaa tacttaggga tgaaagtgca caaactatag
    98281 ctgttttact tgcacatatg gagccagaaa atggagcaga agttttatca tacttagatt
    98341 ttgatttaca aaatgaagta gctatgagaa taagctcaat gggttcaata tctccagaag
    98401 taataaaggt aattgaaagt tcattagaag ataaattaca ctcaataagt ggtgatgatt
    98461 ttaaggatta tggaggagtg tctaccttag ttcaaatatt gattaattct gatagaaaaa
    98521 cagaaaagaa tattttggga actattgaag aacaagaccc ggctttagca gctcaaatta
    98581 aatctcatat atttgtcttt gaagatattg tcaagttaga tgatataagt atacaaaaag
    98641 tattaaaaga agtgactatg aaagatttag tatatgcctt aaagggtgtg gatgatgaga
    98701 tttcagatgc tatatataga aatcaatctt ctagagcagc agatgcactt aaagaagaaa
    98761 tggaaatggt tggtgtcata aaagttacac aggttgaggc tgctcaacaa aagatagcaa
    98821 atatagtaag aaaacttgaa agagaaggtg ccataactat tgtaaggaat tttggtggtg
    98881 actttgttga ataataagat tattaaaagt aaaaaagcat catataaagg agtgctagat
    98941 ttaaccataa tagataaagt tagagtggga gaatcaaatg taaataaaga aaatgattgt
    99001 agatttagag atgaggtaat aaaagaagct atagaatctg ctgagataaa aaagaatgag
    99061 atattagaag aagcaaaaat gaatgcacaa aatatagaaa aacaagcata tgaaaaaggg
    99121 tatagtcaag gtcaaaaaaa tggatatgaa gatggatata aagagtcata tgatgaatat
    99181 acccaaaaag ctaaagatga agcagatttt ataaaaaatc aggcagactt aatactatta
    99241 caagctaatg agaagatgac tgagtacata aaagaaaaaa ataaagagat tgtaagactt
    99301 gctattaata tggctagttc tgttctaaaa aagcatttcg aagatgaaga atctatgagt
    99361 gatttgttaa agcaaattat tcaagattat gaaggaagta gttcatttat agtaagatgt
    99421 aattctttct ataaagataa tatagagaaa gagtttgaat tattcaaaga ggaaacatca
    99481 ctaaaatcaa gtgtatttgt tattgcagat gatagtatag ataaaggcaa tgctatcatc
    99541 caaaaggaaa atggaagaat aatagttggt atcgattgtg ctatggaaaa actaaaagaa
    99601 gaattgcttg gtgaataaag tatgtataaa actgatatat ctatagattt tgacaaaata
    99661 aataagaaaa tagaaaattt agaactcact atatcagaag gtagagtaaa gaagataata
    99721 ggacttactg tagaagttga aggaataaaa gcttttgttg gggagttatg tgttatatac
    99781 aatcaagtca ataaaccagt gaattgtgaa gtagtgggtt ttaaagataa agaagtcata
    99841 ttaatggcgt tgggagagct aacattgata gctcctggtt gtaaagttat ttctaaggga
    99901 atacctttaa gtgttatgtg tagcgataat ttactaggta aagtacttga tggtcttgga
    99961 aatcctatag acaactcaga tgctgtttta ggagatagat acaacttgaa caatgaacct
   100021 cctgacccaa tgaagagaaa aaagatacga aatataatgg aaacaggtgt aagagcaata
   100081 gatgcattta ctacttgtgg tgaaggacag agaataggga tatttgcagg aagtggagta
   100141 ggtaagagta cgactctagg tatgattgct aggaatgcaa aagcagatgt aaatgtaatt
   100201 gcccttattg gagaaagagg aagagaggta ctagatttta ttgataaaga tttaggtgaa
   100261 gagggaatga aaaaatctgt tgttgtatgt gcaacatcag ataaagctcc tttggttagg
   100321 ctaaaaggtg ctcttactgc tactgcaata gcagagtatt ttagagacca gggaaaaaaa
   100381 gtaatactta tgatggattc agtaactaga tttgctatgg cacaaagaga agttggtata
   100441 gcaataggag aaccaccagc tcaaaaagga tatacaccat ctgtatttgc tattttacca
   100501 aaacttatgg agagaacagg gacatcagat aaaggttcta taactgcatt ttatacagta
   100561 ttagttgatg gagatgactt taatgagcca atagcagata caacaagagg gatacttgat
   100621 ggtcatatag ttttatctag agacttggca aataagaatc attatccttc tatagatgta
   100681 ttgaacagtt taagcagact tatgaatgag attgcttcaa aagaagacat aaaaatagca
   100741 tcttttgcga gagatatgct tgctgagtat agagaagcag aagatttgat aaatataggt
   100801 gcatatgctt caggtacaaa caaaaaaata gatgaagcaa tctactatca tgagcatatt
   100861 attaattttt taaaacaagg aataaatgaa aagagttctt ttaatgaaac tataagtagt
   100921 ttaagaagaa tctttgaata aacaatttaa aaaaatattt gaataggttg tgatggaatt
   100981 ggataaaaat tttaagttta gattacagaa agttttagac ttaaaaataa aagatgaaga
   101041 agagataaaa atggaatttg ctaagattca acaaaaaaaa atagatatag agagcaattt
   101101 agaaaactta gaaagtaatt acagcaaata ttctataagt aaaaataatg atagtgttca
   101161 aaatcaaaaa ataactatta actatttgtt agctttaaac aactctataa tggatttatc
   101221 agaagagctg gataagtcga caaatgaact tgaaaaagct agaaagcagc ttataagcaa
   101281 acagatagag agaaagtcat tagaaaaatt aaaagaaaaa aaatatggac agtattataa
   101341 agaagaacag ttaaaagaac aaagcactaa tgatgagttt gcaagcatga gttatttgag
   101401 aaatagacaa gttctataaa atagtaggaa gtgaggatat tattgtatga agatacaagc
   101461 agattcttat aatattatta aagatattgg gaatagaaaa agctcatcta agaataaaaa
   101521 tataaaaaat aataaatttg aagataatct atataaggca acagaccata aaaaggttaa
   101581 agatagaaga gaaacaagta agcaaaatgt tagttcagat aaacgggaaa atagtgataa
   101641 tgagtgtcat ttagatgaag ataaaagtaa tcacttagaa gatgaaaata catatgaaaa
   101701 agattgtagt aataataatg aagctttaca tcaattactg aatcttttaa aagataatta
   101761 caaaaaagat aaagatataa acactatatt gaataatcta aaaaaactaa gtatatcaga
   101821 tgaattaaaa caagaactta agcttaataa aaatatatta aataagattg caaatcaaaa
   101881 tttagagtta aatagagcta gtacaaataa ccctaatgat atagaaaatt tagacataat
   101941 gaagttaaga gaacttttag aaaataatgc tagtgaagat attgaagtaa ttagtaaaac
   102001 tacagaaaat gatactaaaa gcatagactt gtacagtttt gacagcaata gaatagatac
   102061 tcttaactca aataaacaga aagatgatag ttctgatatt ttggaaaaac tagcaggggt
   102121 aaatggaaat aagagtggaa attttggaca agtaataaat aaaagcgttg atatgaataa
   102181 aattaaaaat gataatgtta atttaaaaca gatagaatca aatgtaatgg atgattctat
   102241 aaaagctatt aagcatatga aaacaaatga tatacaagaa ttgacaatta aattaagacc
   102301 aaaagaatta ggagatatga acatacaatt gttaaaagat ggtgaaagta tgagagctgt
   102361 tgtgactgtt ttcaacaaag atgtctttga ctctataaat aaaaacatag cagatttaaa
   102421 gcaacatctt gaacttacaa atgtaaatat aaaagatgta tcagtgcaaa tgcatagcga
   102481 taatacaaat acatctgata cctttgataa agcatttgaa caacagaata gacaaaataa
   102541 ccaagaaaac atgagtaagc aaaatacaaa tgataagcgt aacaatgtag tcatagaaga
   102601 tgagattaaa gaaaatatta ttgatgatga tagagtagat ttactagctt agtaaggggg
   102661 aagtattgca tgtacggaat agcaacggct ttggcaggaa ctcaggtaaa ctataggtca
   102721 aataatttaa gccaacttga aagaaatatt aatgatattg ccaataaaca agttagaagt
   102781 aaaggaaatc agacagtaac agacaatggg actccaatta taggacaagg cgatgatgct
   102841 gataaagatt tgtttatgaa gattcttgta gcacagatgg gtaatcaaga cccaatgaat
   102901 ccacaagacc caacagaata tgtatcacaa ttagcacagt ttgcaacttt agaaaagatg
   102961 tcagctatga atgataagct agatatactt ttagccttaa gcaattccac tctaataaat
   103021 tctgctttga gtatggcaac atcattaatt ggtaaagaag tagaagtatc tggggaagag
   103081 gaagaagatg aaaacattgt aggagtagta aaatccacat atataaaaga tggggaagta
   103141 cacttagaat tagaagtaga tggaagtgac aaaactgtag gtgttaaata tgaaaaatta
   103201 cttaaaatag gagaggtaga tgcaaattca ggagaagaaa atgactcttc agaacaagaa
   103261 tctccagaag aagtataata ttaaatgaga aaagaggtaa atttatgata aaagcaatgt
   103321 attcaggtgt aagtggaatg aaagcaaatc aaacaaaact agatgtaata ggtaacaatg
   103381 tagccaacgc tggaactact tcttttaaga aaagttcagc tagaataaca gattcatttt
   103441 atcaaactgt actatatgca agtgctccaa cagcggcatt agggggaaca aacttaggac
   103501 aagtaggtgt aggtagtaag atatcaagta taaataaaga tatgacacaa ggaaatgtac
   103561 aaccaactaa taggccatct gatttaatga tagatggaga tggatatctt ccagtagtaa
   103621 gacaaggaac agttatgtat acgagagatg gttcttttaa tttagataca ggatttaaag
   103681 cagctgatgg tgctttgaag aatattaaag gtggaagact tgtaaatggt gatggatata
   103741 tgttacaagg tgtgatttat gatggggaat ataaagctga tactggagaa ttcattaaaa
   103801 agggtgatgc taaaggaaaa gagcctattg taataccact tcaaagtata agtcctaagg
   103861 atggaacagt tcaaaatgta ctagagtata atatatcaaa ggatggaaca gtagaatttt
   103921 tattgagtga tggtcaaaga actcaatttg tctatgatat acctgatggt gctaaggtag
   103981 gagatacacc tgctggaata gataaattaa aaggtacaat acaaaaagtg caaacatatg
   104041 cattccaaaa tccagcagga ctagatgcag aaggaggaaa cttattcaag ccatcagcaa
   104101 actcaggaga tccacaaata gcaggagcta caggaaacat aatacaaggg gcaatagaag
   104161 cttccaatgt agatatagca gaagaattta cagaaatgat aatagcaagt aggtctttcc
   104221 aagcaaacag taaaataata tcgacatcag acgaaatact tcaagaaata ataaatctta
   104281 agagatagta ggtacatatt atgataagag taacggattt aaacggaaga agatacatat
   104341 taaattcaga ccttatagtg agaattgact ctgtaccaga aagtaggatt ctccttacaa
   104401 caggagaaaa aaatcttgta aaagagtcag tagatgagat agtagataaa gtaataaagt
   104461 ataaaagaaa agtaaatgta ggttatatta ggagtgaaaa ataatgaaaa aaacagattc
   104521 actaacattc attggactaa tattatctac agtattagtt ttatttgggg cagtaaaagg
   104581 aagtagttca ggattgaaaa gttttttcga ttttgcatct atattaatca cagtatttgg
   104641 gtcatttgga gctttgatga ttacatttac tattgatgat ataaaactta taaaagatgc
   104701 gctacaatac tcattcaaga caatgaatat atcgaaatta gacttattaa atcaatttaa
   104761 aacactttct aaaaaagcaa gaagagaagg acttttatct atagaaagtg atgtaatgaa
   104821 aatacaagac ccatttatga aaaaagggtt agagttatgt attgatggcc ttgaagtaaa
   104881 tgaaataagg tctatactag aactcgaaat agattctgtt gaagaaacca ataacagata
   104941 ttctaaacta tttaaaactt gggggacttt cgcacctgca tttggtatgt tgggaactct
   105001 aataggttta atacaaatgt tatctgacct tacatctcca gatttaatag catcgggtat
   105061 gggaaaagca ttaattacga cattttatgg ttctttactt gctaatatcg ctttgaaccc
   105121 aattgcatat aatatagatg agaagactga aaaagagatt tatgtaaagg aaatgatgct
   105181 ggaaggtata ataagcatac aatctgggga gagcagcata gtagttgagg aacgtttagc
   105241 tacatacctt tcaaacaatg agaagctaga aattatgaaa tccaataaaa atacagaaag
   105301 agcaatgagt aatggcgcgt aaaaaaaata agaaaaagga tgagataaat ccagatgcat
   105361 ggttggctac ttatgcagat actataacac tgattcttac attttttgtg ttattgtatg
   105421 ctacatcagt tgtagatatg gaaaaattta aaaacatagc agatgcgtta aaaggtcagt
   105481 tttctgggat aagtatgttc agtacaggtt caagtacaag tgagaagtct ccaatagaga
   105541 gtgttttagt ggataaaaat gataagtcaa atttagaaca ggatttaaaa gataaagtta
   105601 ataattctaa cttacaaaat agtgtaacag tcaaagatga tagtagaggg attttactag
   105661 aactagatga ttcaatttta tttgactctg ggatttctga attaaaagca gatagtaaag
   105721 ccactcttaa taaagtatat gacatgataa agatgatgaa aaataagata gttatagaag
   105781 gccatactga taatgtacct gtaaaatcaa gtacacatga atccaattgg gatttatctt
   105841 ctagtagagc agtaagtgtt gtaagatact ttgtagaaga aaagggcatg gaccctagac
   105901 tattttcggc aacaggatgt ggagagtatc aacctttggt ttcaaatgaa acagcaaagg
   105961 gaagggctga gaatagaaga gttaatatac ttataactat tgactaggag gaagaggttt
   106021 gttcaaaaat aaaaaaatta ttataattat tttgatactg attattttct cagcaggagc
   106081 aggttttttt atattaggag aaggtggaaa taaacaaatt gacaagattg caggtttgtt
   106141 tattccaaca gggaaaggca aagatgaagt aaagaccgaa aatcttgact tagaagagat
   106201 ggtattaaag ctagctgatg aaggtgtaag atatttaaaa gtatcaataa ctgtatctta
   106261 tgattcttca tataaagata tagaaaaaaa tacgccttta attagggata atattataaa
   106321 ttgttttatg gcaaaaaggg cagatgattt tactgctgat aatttaaaga acataaaaga
   106381 agaaattaaa aatacattaa atatacaact aggtgaaaat gtaattcaaa atatatattt
   106441 cacaaatata gtagtgcaat aaaaggatgg taagacatga tactttattt actaaaaata
   106501 ttaatatgta tcccaataat tttaatattg atagtcttat ctttaaaaat tagccaagga
   106561 actttattaa aaaaatataa tgataaatat ataaaaatac tagatattgt aaatataagt
   106621 aaaaacaata gcataataat tttaaaaata ggtgaagaag gatgcattat ggcatcttct
   106681 tcctctagca tgaataaaat aaaagatttg accaaagaag aaatattaag aatagaaaac
   106741 gacattaaag aaagaaattt taaaattcaa gattttaaaa tggaaagaat taaaaagaaa
   106801 tatgatttca gtagatatat tggaaaattt acaaaaaagg aagataagta aatggaacta
   106861 ttatcaaaat tacctttggc tgatgtacca tatacaagtt caatgcaatt gtttttattt
   106921 ctaactgcat taatgttttt accatttgta atgtttatga tgacaagctt tgtcagaata
   106981 gttataagtt tatcattttt gaaatcagca ttaggagcac agcaagcaat tccaagccaa
   107041 attttggtag ggcttgcaat agtattgaca atatttataa tgagaccagt attaaatgag
   107101 ataaacgaaa aggcattaca accatatatg aaagaagaag ttactatgga agaagctatg
   107161 aaggaagcag agggacctat taaagaattt ttattaaagc aaaccagaca gacagattta
   107221 gatttatttg tagaacaggc tggtttgaaa gaaaagaaat taactcgtga aaatatacca
   107281 ctatctgttg tagttccagc atttgctata agtgaactaa aaactgcttt tcaaataggt
   107341 tttttaatat atataccatt tttgataata gaccttgttg tggcaagtgt tttgatgtct
   107401 atgggtatgt ttatgttgcc tccagtcatg atatcattac cgtttaagtt attattattt
   107461 gtaatggtgg atggatggaa cttgatagta aaaacattga tattgggatt tggataggag
   107521 aaaaatagta tgagtgaatt tatgataatg agtgttctta aaaatggcat gtttacagga
   107581 gctatgattg cagctccagt actcattgtt tctcttgtag ttgggctttt aataagtgtg
   107641 tttcaagcta caactcaaat ccaagagcaa actttgactt ttgtaccaaa actaatagca
   107701 attcttttag tagtagctat tggtggaagc tggatgttac atactcttat tagctttact
   107761 tcggagatat tcaatatgat gtctcttata actaaataag taggatatat atgatttttg
   107821 tatttattag aatagtggca ttctttggaa cactaaggat actatttcca gctggtacac
   107881 ctgctttatt taagtcgctc tttgcaatca ttatatcaat attgatttca agtactatgc
   107941 aaattgaata tgcaacaaat atagacaaca ttgtattgtt taccttatat ggtataaatg
   108001 agaccataac tggcattatg cttggatata taaccaatct atgtttttat agtatcagaa
   108061 tggcaggttc tatgatggat caacagatgg gattatcaat gattaatatg tttgacccaa
   108121 attcaatgac tcagacaact ttaattgata atcttatgaa ctggacagca cgtatgatat
   108181 tttttagcat ggatggtcat catgttttaa ttagaggcat aaggtatagt tttgagttaa
   108241 ttccaatagg gaaatcattc gtagataata atatagatta tataataaac atatttgtgc
   108301 agtgcttttt aactggattc aaaatagcaa tacctattgt actttgtctg cttatggcag
   108361 attttatatt agggcttata tcaagaagtg tacctcaact aaatgtaatg ataattggta
   108421 tgccattaaa aatactggtt ggtattgcgt tatttatcat atcaatacct ttaattgtca
   108481 atcaaataag tcatttatta agtcaaatac caaagatgta tgagggaact ttcgcactag
   108541 ctcctatgtt ttttatgggt tcaacagata aaacagaaga ggctactcca aagaaaaagg
   108601 gagaacaaag aaaaaaaggt aatatagcaa agagtaaaga attacccgtt gcaatgactc
   108661 tacttgcatt cactttatta gtacctacat tattttcata tgtagtggat acacttaaat
   108721 cttctcttaa ttattttttg agtctagatt tttatatgaa tataaattat tcaagtatag
   108781 agaaattagt tatagcagga ttaatggatt tttttaagat atttttacca atagctattc
   108841 cattcttagt tttaggtata gtcgcaaacc tatttcaagt gggaatactg tttactggtg
   108901 aaactttaaa acccaattta tcaaaattaa atccagttag tggatttaaa aacatgtttt
   108961 ctatgagaag tttgtcaacc ttaataaagg atacagcgat tatatctatt ttggcttaca
   109021 taggatatac attcttccaa gataattatt tagatatatt aaagctaggt aacatatacc
   109081 tgccaacttt aatgtacaca gttaaagatt tagtatattc aatattaagt aagatttgtg
   109141 tagctatgat agttatagca gttgcagatt atgtttatca aagatacagt cataaaaagc
   109201 aacttagaat gacaaaacaa gaagttaaag atgaatataa aaactcagaa ggagacccag
   109261 aaataaaagc taagataaaa caaaaacaaa gacaaatttc gtctcaaaga accatgcaag
   109321 cagtaccaag tgctactgta atagtaacca atcccaccca cttatctata gcagtgagat
   109381 atgaaaaagg gaaagaccaa gctccagtag tggtggcaaa aggtgcagat tatttagctt
   109441 ttaaaataag ggaaattgca aagggaaatg acatacctat aatagaaaat aaacctattg
   109501 ctaggttgtt atataagcaa gtagaaatag accaagaaat tccagaggac atgtatcaag
   109561 cttttgcaga gatattagta gcagtatata aaatcaaaaa tagatacaaa gtcctcaaaa
   109621 ggtaggataa gtaatgaata agtttaattt aaaggaaaat atggacgtaa tagtggcatt
   109681 tggtgttgta gggattgttc ttatgatgat agtgccgtta cctacattta tattagatat
   109741 tttactggca attaacataa gtttatctgt gctaatttta ctaatgacat tatttacaac
   109801 aaatgtactt gatttatcta tatttccaac agtgttactt gtgacaacac tatttagatt
   109861 gggattaaat ctttcatcaa ctagattgat tttaacacag ggatatgcag gtgaagttat
   109921 agaggcattt ggaagttttg ttgtaggtgg aaattacgta gtaggaataa ttatattctt
   109981 aattatatta attgttcaat ttgttgttat aaccaatggt tctggaagag tatctgaagt
   110041 aacagctaga tttacgttag atgccatgcc aggtaagcag atgagtatag atgcagattt
   110101 aaatgcagga gttatagatg acaaaactgc tagaaaaaga agaaaagagc ttcaacaaga
   110161 agcagatttt tatggctcta tggatggagc aaataagttt gtaaagggag atgccatagc
   110221 aggtcttata gtaacagcaa taaacataat aggtggaatt gtaataggag ctgtaatgct
   110281 gaatatgact cttatgggtg cagcacagac atatgtaaga cttactatag gggatggtct
   110341 tgtaagccag atacctgctc tattaatatc tacatcagcg ggtataatcg taacaagagc
   110401 ttctactgat gaaaactttg gtggattagt aagtaaacag ttaacggcaa taccaaaagc
   110461 agtaatgatg actggttgtg ttctaatcgt acttggtatg atgcctggat tacctaaacc
   110521 agcatttttt tcactaggta taggtgctat agcagcaggt tactttttag gaagagaaaa
   110581 gaaagatact ttagaagact tggagtttga aaaacctgat atggtaaatc cagataaaaa
   110641 tgaagtagaa gatgtaacaa acttaataaa tgtagaatca atagaagtag aaattggata
   110701 tggtttaata tctttagctg atgaatcagc aggaggagat ttacttcaga gaatagcatc
   110761 aataagaaga caatgtgcaa tagacatggg tatagtcgtg caacccataa gaataagaga
   110821 taatttacag ttaaatccaa accaatacaa tataaaaata aagggaaatg tagttggtgg
   110881 gtatgagata atgcctaata tggttttatg tatggaccct atgaatcaag gatttagtat
   110941 atttggaata aagacaattg agcctacttt tggaatagag gcactttgga tagaaagtga
   111001 caaggtagaa gatgcagaga taaagggtta tacagttgta gattcatcca caatacttat
   111061 aactcactta ctagatataa taaaatcaaa tgcacacgaa ttactgggaa gacaagaagt
   111121 taagactatt atagatgcag caagagaaaa ttatagtgct gtagtagatg aattgatacc
   111181 agatttaatg acacttggtg aaattcaaaa agtacttaaa aatctgttaa gagaaaaagt
   111241 aaatataaag gatagggtta caatacttga aacgcttgca gaccagtcta gaaatacaaa
   111301 agatatagag cttcttactg aatatgtaag aatagccttg gctagaagta tttgtaataa
   111361 tttagttgat gatgataaga caattgtagt ggctacattg tctccagaaa ctgaagagtt
   111421 ggtatctaat aatttacaaa ggtctgtaaa tggaacttat ccagcagttg acccagaaaa
   111481 tacaaataaa atatttgaga gtatacaaga agtaatgaac aatgtatatt tcaatcataa
   111541 tataccagta atagtagtat caccaaagat aagagctcca tttagaaaat tagttgaaat
   111601 tgtatatcct aatttgactg tattatcatt aaatgaaata cctaacgata ttaaaatcaa
   111661 agcagaaggt gtggtgagca tatatgatga cgaaaaagta tacagctaac acaattcagg
   111721 atgctatgaa tctagccaaa atggaattgg gtgacaatat tacattaata gataaaaaag
   111781 aagtaagaaa gtctggaata caaggtatct tttcaaagaa agatattgaa ctaactattg
   111841 gatgggaaaa gagagaaaac gtagaacaaa aagatttaaa acgagagata gaacaattaa
   111901 agttaattat taacaatatg gggtttgata ataagaatga taatgatata gataaaatat
   111961 gtaaaaatct actaagttta gaattaaatg aagaaattgt agaatctata agaattgatt
   112021 tgcaagaaat gaagttcaat ggaattgata caagcaaaaa tttagtagaa attttaaaga
   112081 aaaagattaa aatagaaaat caagcaataa atggtaaaat tgctctagtc ggaccaccag
   112141 gagtaggtaa aacgactaca atagcaaagt tagccgcaaa attagttttt gaagaaaata
   112201 aaaaagtagg agtaataact atagatacat acaggattgg tgctgtagaa cagttgaaga
   112261 tatatactga tataatgaat attcctttta aaggggtaat aagtcccgat gaaatggaat
   112321 tggcacttga tgagatgaaa gattgtgatg ttgtattaat agatacaaca ggtagaggct
   112381 ataaaaactc tatgcaaata ctagaaatca aaaatcttat agataaagct gaaactgata
   112441 atatacattt agttgtgaat tgtacaacaa gagaaagtga tacaaaagca attatagatt
   112501 catatagaaa tgtgaatttt aaaagcttaa taattacaaa gctagatgaa acaataacat
   112561 atggctcaat atttaacata atgaattatg cacaaaaacc aatatcatat attacaacag
   112621 gacaaaatgt tcctgatgat attataaaac ctaatgaaga taagattata aggttactat
   112681 taggagttga aagtatatga tagaccaagc tcaaattttg agaaaaatgg caatggaaaa
   112741 aagaggactt gatgagttta tagtagagaa tgagaatgta cctaagataa ttacaatagc
   112801 ttctggtaaa ggcggtgttg gaaagagtaa tctcgctaca aatttgtcta tatgcttgac
   112861 caaacttaat aaaaaagttc ttatattaga tgcagacata ggaatgtcta atatagatat
   112921 aataatgggg gtaaatgtaa aagggactat aattgatgta attaatggcg aaaaaaatat
   112981 agaagatata atttcacaga ctaagtatgg tgtaaatata atatctggag gttctgccct
   113041 taatcatata gaagacttta cagaagctca aagaaataag tttatacata gcatagaaca
   113101 gattcacgat gtggatttta taataattga tacaggagct ggtatgagca aaagcctatt
   113161 gtcatttata tactgtagta ctgaattttt cttaataaca actccagaac cgacatcatt
   113221 gactgacgca tatagtttat taaaagctat aagtaatttt ggcataaaga gaagtgcaaa
   113281 tataataatc aatagggtaa ttgatttaga agaagcaaaa tctacataca aaagaataaa
   113341 aatggttgtg gacaaatttc taaaccttaa tctagaattg tatggatata taatagatga
   113401 caaaaaagta agtttatgtg taaaaaaaca gataccattc attttagaat atcctacaag
   113461 tattgcatca aaatgtatta tagccatagc aaagagaatg gtaagtcagt caagagaaga
   113521 tattgttgat aataaaagtt ttctaagaaa gatgtttagt atatttaaaa gctaaggagg
   113581 cgtagttaat gaatagagaa gaattaataa aagagaatat gcctcttgta aagagtatag
   113641 caagaaaatt ttttatacca gggaaaggtt ttgaatatca agacttagta aatagtggag
   113701 tcattggatt gattgatgca ataaataaat ttgatgctga aaagggggca aagttttcta
   113761 gttactctta tataaaaata aaatctgcta tattagatga aattagaaat caaagtccaa
   113821 tttctaaaca taatctaact aaagtaaata agtataatag agtggtagaa aagttgcaat
   113881 ctaaattatt aagagagcca acttcatatg aaattgcaaa agaattaaat gtttcagaaa
   113941 aagaacttca tgatatcgaa agtaatatag acatgttaaa tattgtatca ttaaactatg
   114001 taatctttga agatacaaat gaaactgtac aagatgtaat aagtgataga gaagaggaag
   114061 ctccagaaaa tataatagaa gaagaagaaa agttagagat tctatctaaa gcaattagta
   114121 atttaaatga aagagaaaaa ttaatacttt cactgtacta ttatgaagat ttaaatctaa
   114181 aggagatagg gaaagtgcta ggtgtttcag aatcaagagt ttcacaactc cacagaaaat
   114241 caataagaaa cttaagaaac aagataaaag aacttaaata ttctatatag atggtgattg
   114301 ataagatgat acaaattata ttaatagtag tgtctatttt aataatagta actatagtta
   114361 taaatttaca taaggaatca aaaaataaag ataacagata ctttgataaa atatttgagc
   114421 aagaatatga agcaaatgat agattaataa ttgcagaaaa aagaagattc tttttagaca
   114481 aagtacttgc tgaaataaga agtaataatc atataaaagt ttatgaaaat tataacctaa
   114541 taaaggctaa tgaagaaaga aaggaaaaca tatttataga atcaaaaaag gaagtaagac
   114601 aagaaaatga gttatctctt aaagtgaaac atcttataag ttcaggttat gatgatgtgg
   114661 aaatatgtaa gatgctagat attggaaagg gggaactgtc attaataagg agttgttaca
   114721 aaatataagg atattattat gtgataaaaa agtattctta ggaataggta ttggtatatt
   114781 aatatcaact ttatgcataa tgctttttag taataatgat atgagtaagg cagagataga
   114841 aaaaaaggcc agagcgttag gcatgaaata tacaagtgag atgaaagttt tagaatagat
   114901 gatactgttt agacatttac aaaaaaggag gtcataatgt gataagagga ttatatacag
   114961 cagtttctgc tatgataact aatcaacaaa agcaaaatgt tgttgtcaat aacctagcta
   115021 atatggatac aaatggatat aaaagtaaac aacttttgac taaaagtttt gatgaattaa
   115081 agttggaggg ttacaataac tacgcaaatg gaactaaaca aaagcagatt ataggcgata
   115141 taagtccagg tatttctatg gatgaaacta tcacaaattt taatcaagga cctataaaaa
   115201 ctactgataa taaaatggat gtagctattc aaggtaaggg attttttcta gttagtgatg
   115261 cagctggaaa tcaattttac actagaaatg ggaacttcag aacagacaat caaggtgacc
   115321 ttataacaag tgaagggtat tatgtacttg ggacgaatac tgctactggt gctgtaggtc
   115381 atataaatgt aggaaatcaa aaatttgaag tggcaaaaga taatacaata tcactagatg
   115441 gaaatgctat gtataaattc aatattgtag attttaatga ctacaataac ttaaaaaaag
   115501 aaggagataa cttgtattct ggaggaggag ctatgaaagt aaataatgca cttacaatac
   115561 aaagtgcgat agagtcttct aatgtagata tggtatctga aattaataat atgatgacca
   115621 tatcaagaga atatgaggca aatcaaaaga taattcaggc tatggattct aaattagcaa
   115681 aaatagcaag tgagattggt tcagtaagat aggtgatagg aggtgaattt ttatgtacac
   115741 aatgttttat actagtaaaa cagctttatc agcaaatcaa agtaaactag atataatatc
   115801 taacaatata gcaaattctg attcaacagg atataaaaaa ataaatatgg aatattctga
   115861 tttagtggat gaagtactaa atagaccatc atatcctaca aatggcaatg atatatcgac
   115921 tggaacagga gctaaggcaa cagctcccat gagaatttat gaacaaggtg cattggcccc
   115981 tacagatagt aagagtaatt tggcgataga tggagaagga ttctttagag tgataagaaa
   116041 agatggtaca tatgcatata caagaaatgg tggatttaat atagatggtt taggtaagat
   116101 tgtagatgat aatggaaata tattagatgt tcaatttgat gcaggatata actataataa
   116161 tacgaatata gatagcacaa acttaacagt ttcaagaaat ggcgagttat tcgtagataa
   116221 taaaaaaata ggaaaaatca atttatatca acctatagga actcaaaatt ttatatctga
   116281 aggagatagt ttattcgtcg caactgatgc agcacagatt aaacaagttg agaaagtaga
   116341 tatagttcaa ggctatagag agaggtcaaa tgtttcttta caagaagaat ttgttgactt
   116401 aatagccact caaagagcat ttcaaatgaa ctcaaaggga ataaagacag cagatgaaat
   116461 gtggcaaata gctaataatt taagagctaa ataattatgt aaggtgagga atattcatga
   116521 atgatatgaa agagtacgat tttggcaaac ctcagagtta ttcaagagaa aatttaactt
   116581 gtttaaattt tttattagct gaattttgta aaaaatataa aaactatata atttatgaac
   116641 ttaagtgtaa ttctagtatg attgttgata gtatagacca agtaaattat cagacttttt
   116701 tagatagagt aacttcttca tgtgtagtag tacaaaatgc aatggaacct gttatgaaaa
   116761 acttttcttt tagaatagat agaagtgtag ctgatatgtg gattgatata acttctggag
   116821 gaactggagt tataaaggat aatgatagag agcttacaga acttgataaa aaagtgcttt
   116881 tacatcttat ggatgattta gtaagaaata tgcacttatt tgaaggtttt gaaaatatac
   116941 aagtattgga tacacataca catattaatt taccacaatt atgttctcca actgcaccag
   117001 tatgcgttgt agatttaaaa gtgctaaatg ataatgagta tattggaagt gtttctcttt
   117061 gttttccgta taatggttta gaggctctat tagaaagtat atctgttata gaattttttg
   117121 ataatgatgt aggagatgat tcagaggaat ttaccaaaaa aatctataat agtgtatcta
   117181 atatagaatt atcagttatt gcagagatag gaaaagtatc aattaatgtt gaagacttac
   117241 ttaaactaga agttggagat gtaatagtaa caaataaaaa aataaatgat tatatagata
   117301 tatttgtaga aaattcaaaa tcatatacag caacaccagg atttatatca agcaaaaaag
   117361 gtgtaaaaat aaatgatgct gttggaaaag aggtgtagtt atggacaata gtaatcttat
   117421 ttcagatgaa gaagcaaaga tgttattaaa tgataaagtt gaaagtgaag ttgatgggga
   117481 tgatgagtta gccttagatg tctctgaagt taatcgaaat aatatacaaa ggatacttga
   117541 ccttaagtta gaattatctg tagttatagg gagaactaag atgactctaa gagatatttt
   117601 aaatttacat aaaggttctc ttattgaact gaatacttta gcagaccaag atgtggaaat
   117661 actaatagat aataaggttt tggcttatgg aaaagtagtg gtggtagatt taaattttgg
   117721 tgtaaagata acaagtatag taagtgaaga agacatggta aaatctcttg tttagagata
   117781 acatcaatta atacttaagg catgaggtgg tacttatttt aaacttaaat gatataaaaa
   117841 aagatatact aaaactcaat aaaaaagact catgttctct atataatgaa tctattaata
   117901 atataaataa taattgtata tcaactggat taaaattttt aaaacaagca agagatttaa
   117961 acccagatga tgttgatata ttaaatctca caggtcttgt aaacttacta aaatgtaatt
   118021 ttgatgatgc tgtagaaagt ttctataaga gttcactttg tgaaaaaact gctctgtgtg
   118081 aaaagtatat aaacatgctt acatctgagg agtttttaat tttctttgaa aagtacaatc
   118141 aacttataag gttaataaat aaaggaatgt ataaagaagc tatacaaggg tttaaactta
   118201 taactgacca atactgtgat ttaatagaac cttatgagtt gcttgcctta ctgtatgaca
   118261 aggaagaaga atatataaaa tttgatgaat gtttagaagt attgaagatt attgataagg
   118321 aaaattattt attaaatcaa gaaaataaca cattagatat gtataatagt gctaatatac
   118381 aaactaaaag taatgtaaaa gtagatgatt ataagaatga gtttttacat aaaagtagta
   118441 gtaaccataa aattaatgat tataataatg taactaaaga aaaaagttca agcaaaaacc
   118501 agaaaagttc agattctaat aagaaaaaaa gtattaaaaa aaataagtac ctatatatag
   118561 ccataatatt aggaatatta ttagtaggac aaagtatata tagttcttat aagatgaata
   118621 atttaactga taaaatatct aaaaataatg aaactaaaaa tgaagagtca atagattcta
   118681 acttgactaa gaaagaaaat aatatagaag aaaatgaaga tatgagtaag gcttctaata
   118741 taaataagag taataaaaac attaataaag aggctgatgt aaaatctaaa aaaaatactg
   118801 tagaaaatga agatgataaa gattctgact tatttacaga ggatgaattg atgtctaagg
   118861 cgaatacttt aaaatcagaa aaaaaaacta aatcttctat acaactatat aagaaagttg
   118921 cagatatagg tgaaaataaa gggaatacat ctgaagcaac ttatcaagtt gctattctca
   118981 gtgaaaagtt aaaagactat aaaactgctg aagaatatta taaaatgtat gtagaaaatt
   119041 actcagaaaa agatgcttat tttgatgaat cttattataa tttagggatg atgtactata
   119101 acaatggtga tttaaaaaat tctaaattga cattaaagaa gttagttaat aaggtaccaa
   119161 atagtatgta taataattca aaagtaaaag aaattttaaa agaagaatag ttaaattaga
   119221 taagaaaaat aaattatttt attttaaaat aatatgatta taatatattg acataccatt
   119281 ttaaaaaatt taaaatatta attataaaat gaggagggat aaaaaatgga atttgaaaaa
   119341 gggagtattt caattcatac agaaaatatt tttcctataa ttaaaaaatg gttatactct
   119401 gataaagaca tatttataag agagcttata agtaatggat gtgatgcagt aagcaaacac
   119461 aaaagacttg tatcactagg agaaatatca gaaaataagt catcagatta taaaattaca
   119521 gtatctgtaa ataaaggaga aggtacactt aaatttattg acaatggaat tggtatgact
   119581 gaagaagaga taaaaaaata cataaatcaa gttgcttttt caggtgctga agatttcttt
   119641 aataaatata aggataagat ggaagagtca aatgacataa taggtcattt tggattagga
   119701 ttttattctg catttatggt gtctaaaaag gtacaaatag atacactttc atatacagaa
   119761 ggagcgactc ctgtaagatg gatatctgaa ggtggtacag aatacgaaat atctgaatca
   119821 gatgctagaa atgatagagg aactactata acactattta ttgatgatga tagtaaagaa
   119881 tttttagatg aatttactgt aagaggaata ataaataaat actgttcttt cttaccagta
   119941 gaaatatatt tagaagatgt tgaaagatta gaaagagaag ctaaagaagc agaagaaaaa
   120001 gctaaaaaac aaaaggaaga tggaaaagaa gagattgtag atgcaaaagt aattgagcct
   120061 ttaaacgaca ctaatcctct atggttaaaa tctccaaaag actgtactga tgaggagtat
   120121 aaagagtttt atagaaaggt attcaatgta tttgatgaac ctttattttg gatacattta
   120181 aatgtagatt atcctttcaa tttaaagggt atactttact tccctaaatt aaaaaatgag
   120241 tttgaactga ctgaaggaaa agtaaaatta tacaacaatc aagtgtttgt ggctgacaat
   120301 ataaaagaag ttataccaga atttttactt ttattaaaag gtgttataga ctgcccagac
   120361 ttaccattaa atgtatcaag aagtttctta caaaatgaca gggatgtaag caaaatttct
   120421 aaacatataa ttaaaaaagt agctgataag ttaaaatctc tttgtaaaaa tgaaagagaa
   120481 gaatacaata agttttggga tgatatacaa atatttatta aatatggttg cttaaaagat
   120541 gaaagtttct atgagaaggt aaaagaatgt atattattca aaactattga tgatgagtat
   120601 ataacaatac aagattattt agaaaaatgt aaggacaaac atgaaaataa ggtattttat
   120661 gtaagtgata aggaacagca atctcaatac attaaactat ttaaagaata cgacttaagt
   120721 gctgttgttt taaactcatc aatagatact cattttattt catttatgga atataaagag
   120781 aatggagtta agtttaatag aatagatgca gacctttctg atgtattaaa agataaaaat
   120841 gaaaataaag atagtgaaga aaacaaagaa gagatagcta agatagaagg tttgtttaaa
   120901 gaagctgttg gagaaagagt gaagaattat tctgtagaag gattgaaaaa tgaagacact
   120961 ccagctatgg tattagtatc agaacaatct attagaatgg cagaaatgca gtcaagattt
   121021 gctggaatgg atttaggaat gaattttgag gaagaaaaaa ctcttgtaat aaatgagaac
   121081 agtccaataa tcaaaaaatt ggtttctctt aaagatgatg aggaaaagaa agataagatt
   121141 acgcttattt gtaaccagat agcagattta gctttacttt ctaataaaga attaaagcca
   121201 gatgagttag attcatttgt acaaagaagt aataagctta tgagtctttt gatagaatta
   121261 taagattgaa tttgaataca ttgaagcaaa tttataaaaa gtattcaata tcagtgatga
   121321 gaaagaagtg tctcaaaatg aacttttcag ttcatgaggc gcttttttta tgtgaaatta
   121381 aatttatttt aatcatttca acaatgaaaa atatatttat ctctattttg agacagaccg
   121441 ttctttattt ttttatcttt ggttaatttt taaatattta agtaggttct aataaaaaac
   121501 tctatttagt taaatatagt taacttgata tataataaga taatacatat aattaagtaa
   121561 aagattgttt tttagtttat gtttaaatac ataattacac tttgttaaaa acataaaatt
   121621 attactaaag tagaaatagg aggttttagc atgaatttta attataattt gccagtaaat
   121681 atcttatttg ggagaggcag aattaatgat gtgggaaaag aagtatctaa atatggcaaa
   121741 aaagtattga tagtaacagg taaaaatagt acaaagaaaa ctggattact tgataaaaca
   121801 atagatttac taaaagactc taaaatagaa tatgaagttt ttgatagagt agaacaaaat
   121861 cctcttataa ctactatata ttcaggcgta gaaattataa aatcaactgg atgtgattgt
   121921 gttttagggc ttggtggtgg aagcattatg gatgctgcca agagtatagc tttttcttat
   121981 aaaaacccag gagatttaaa tgattatata tttggaatta gacaaggtga agaagcttta
   122041 cctataatct tagttccaac aacatcaggt acaggtagtg aaggaaattg ttttgcagta
   122101 cttacaaatt cagaaactaa agataaaaaa tctataaaga agaatagtat gtatgcaaaa
   122161 gcatcaataa ttgacccaga acttatggtt acaatgccaa agcatataat tgcatcagtt
   122221 ggatttgatg cacttgccca taatatggaa gcatatcttt ctaatggaag aaaccctctt
   122281 gcagatgtac aagctattta tgggattgaa cttatatcag aaaacctaat aaaggtatat
   122341 aatgatgtta atgatttaga agcatgggaa aaaataacac ttgcaagtac tattggagga
   122401 atgacgattg gtacagcggg tacagccttg ccacatggaa tggagcatcc tgtaagtggt
   122461 cttagagatg taatgcatgg aaaaggactt gcagcgttga ctcctactat tatagaaagt
   122521 tcatgggata ttgatattga aagatttggt aatatttcaa aggtattagg aggaacttgt
   122581 gcagaagatt gttcagatgc aattagaaat ttccttaaaa aaatagattt agatataaaa
   122641 ctaagtgatt taggtattga aaaatcagat atagattggt taactgataa ttgtatgaaa
   122701 atatcagttg caaatattaa gagacatcca aagtatttta ataaggaaca aataaaggaa
   122761 atgtaccata agtctttata atttgacttt acatatttag ttttatataa aaattataaa
   122821 ttaataataa aaaattataa gtaattaata gtaaaaaaat tgtgtataga agttatatat
   122881 ataataaact tgtcttaagc ttttatttta ctttctaata aataaaggag tttaaaaaag
   122941 ggaagattaa ttaagtaata ttttataaaa ttcttcgatt taaaaacttt aagtagaggt
   123001 gaaataaatg tttaatccca aaagaataat attcgaaaaa ggaactttag acactgatgt
   123061 gggcaaaaaa atatacaata aatttagaga taataaagat gtagagataa ttaatatatc
   123121 atcaaatagg attaaagaac acattccagg tgaaaatcta tatgaacaat atagaagtgg
   123181 gaagcagact atggtagttg ggattagaaa aagtctgaag tttcaaacat gtaaaccttc
   123241 tgctaattat caactaccac ttgtcagtgg atgtatggga agatgtgagt attgttattt
   123301 gaacacacaa ttaggtgata aaccatttat aagggtgttt gtaaatgtag atgaaatact
   123361 tgaacagaca aaaaaatata ttgaagatag aaagccacag gtaaccatat ttgaaggggc
   123421 agctacatca gacccagttc cagtagagcc atatactaat tctttgaaga aaacaataga
   123481 gttttttgga agagaggaaa aaggaagatt tagatttgtt actaaataca gtgatgtgga
   123541 tagcttattg gatgctgaac ataataatca tacagaaata cgatttagta tcaatactcc
   123601 tagaattata aatgaacatg agcattatac agcctctgca aataaaagaa tagagtcagc
   123661 tgtaaaactt gctagggctg gttatcagat tggtttcata atagcacctg tgtttttata
   123721 tgaaggttgg aaagaagagt ataaaaatct gattataagt ataaaagaag ctttaccaaa
   123781 ggattttgat aaaaaaatta tatttgaagt tatatctcat agatatacaa ctaaagcaaa
   123841 aaatagaata ctagagattt atccagatac actattgcca atggaaaatg aggatagaaa
   123901 gtttaaatac ggtcaatttg gatatggtaa gtacgtgtat gataaagaac aattagatga
   123961 tatgaaagag ttctttctta aggaaataaa tggagtattt aaaaatagtt taataaaata
   124021 tataatatag caaatcttac ctaaagattt gctatatttt atttttatat attttatgtt
   124081 tataataaag caatgagatt tagcactatc atataagaaa attaaaaagg gcactatcta
   124141 tcaagaacat tttttctagt tttgatacta taaagggtaa gagtaacaaa aatatcagga
   124201 ggagttatag tatgcatgca tgggagtcta ttcaaattac attggattta atagaagcaa
   124261 atttatcaga agaaatatca attaatgaat tagcaaataa agcaaattta tcaccatttt
   124321 actatcaaag actatttaaa agattggtaa ataagactgt aatggagtat ataaagcttc
   124381 gtcgtcttgc aagagcttct gaatacttag cagaacataa gaatcgtata cttgatgtag
   124441 ctttaaattt tggatttgct agtcatgaga catttacacg ttcctttaaa aaagcatatg
   124501 gattaactcc agaaaaatat agagcaaatc cagtaaaact caatcacttt attaagccag
   124561 aattaatttt aaattatgct atggttgatg aaggtgttcc actgattgca gatgatatag
   124621 tgattgaagt caatcgtaag acattgagta atccaaggac atttgttgga atagaaatag
   124681 aagtacctat ttgccagttg gtgggtggtg aaacaactgg aattgcaata gtagaggaat
   124741 tatggatgaa acttggaagt caaagacata atataccaaa tcaaattcca ggtggaaatg
   124801 aatttgctgc tctttatatg ggaaatgcaa aagaaggaaa ttgtatgtat atggcaggtg
   124861 tagaggtaga gtcaggtaca tcagtagaag gatataatac ttttgagttg ccagctaaag
   124921 aatatttagt atgtggattt gaggcagaaa actttaatga gttagttaat tcagctgttt
   124981 ttaaagcaga taaatttatg gaaagatgga tgaagaaaca taatttaaca actactgatt
   125041 ttgcaattga gatgtattac cccactacac ctgaagcagc atatctggaa cattggattg
   125101 ttccggttcc tattgaacaa tagaaaggat gatgaatatg aattggcaag atgcgttttt
   125161 tcaagatact aaacctacat ttgagcaaat taatgaattt attaataatc cattatggga
   125221 caagttaaat aaaactttgg tttctactta taatgtagaa cctaagcttg aatacagtaa
   125281 atgttcaatg caaagaggtt ggaatgtaaa atataaaaaa agaggtaaat cactatgtac
   125341 tttatatcca caagaaggtt attttaaagc tttggttatt gtaagtgaaa gcaatagagt
   125401 agaggttgat ttatttatta atacttgttg tgattatatc aaaaaaatat ataatgaggt
   125461 aaactttttt aatggaagta aatggctaat gattcaagta gatagtttat tggtattaaa
   125521 cgatatgctt gaactaatta aatttagagc ttaacatata gaacaggatg aatatataag
   125581 tcatcctgtt tttatattca atcagataaa ttaatatata gtctataata tgaataattt
   125641 agtaaattta ctttatcttt ctacattctt tgcaactaag tccacatgtg tttttttctt
   125701 gcatattagt agcaccccaa ttagcaaatt gttgtaaaat aggcacaata cttttacctt
   125761 tacttgttaa tgtatactca acttttggag gaatttcatt atattgttta cgatgaacaa
   125821 taccagtaga ctctaaatct tttaatgatt gagctagcat agtatttgta atgccatcca
   125881 attttctttt tatgctacta tatctaattg gattttcaac tgctaacata catataatag
   125941 gtaatttcca cttaccaccg acaatgtcta atgcataacg gattggacag gttaattctt
   126001 caacgttttt agttatattt ttttcagtat ttatactcat tttaattact ccttagttat
   126061 agtagtatct tttttatact ttatcagaaa aaactgcata cttgtttttt ctgtatttta
   126121 tattaaaatt atatcaaagg ataatcctta atacaagtat ttaaaagggg tgtaagaatt
   126181 atgaaagcat tagaattttt gaacaaggca ggagtttatt atttagcaac agttgatgag
   126241 aacaatcaag cacatgtgcg tcctttagga tttgttatgg aatacaatgg taaacttaca
   126301 ttttgcacat ctaatcaaaa ggatatgttt aagcaactta tttttaatcc aaaggttgaa
   126361 ctttgttgta tagaccaaaa ccttaatact ctacgtattt taggtgaagc agtatttgtt
   126421 acatcaaaag aaacacaagc taaggcactt gaaataatgc caagtttagg tcagatgtac
   126481 tctgtgggag atggtaagtt tgaaatattc tctattgata aggcaaaagt tagttgttgt
   126541 tcaatgagtg gtaaaaagat tgatgtagag ctttaattat aattgaatcg acatccatag
   126601 tgaaaattaa gaaaacgtta ttactgaaat attgatagat ttaatttaag tgcaataaaa
   126661 agatttttaa ataatgaata tgtaaaaatt tttagttatt agatgtgtat ttcaataatg
   126721 atatactatt ttgaataatt acatactaga
//
LOCUS       DAMJWO010000002       108965 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.002, whole genome shotgun sequence.
ACCESSION   DAMJWO010000002 DAMJWO010000000
VERSION     DAMJWO010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 108965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 108965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..108965
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.002"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            107..736
                     /locus_tag="PC366_000122"
     CDS             107..736
                     /locus_tag="PC366_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HDF2575686.1"
                     /translation="MDENITKNNYNVPFDYVRKKLKELDPHTISNLSNIPFNNDLNRF
                     TLNFFDRQYIIDYPSGEVWNSNGSLCNNFELKILIVRYLINAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLNRTLYRLSEVFTSQIDKYKLVMEKIGAEKVNMGDLAYRFTYMGNTSMI
                     FILWFGDDEFPPNSNILFDSNIVYYFNAEDLAVVPDTAINAILNKINQL"
     gene            804..1637
                     /locus_tag="PC366_000123"
     CDS             804..1637
                     /locus_tag="PC366_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HDF2575687.1"
                     /translation="MNVENQSLSDIEIILSHRYDNGADYWTTPDKRLIKGSPFSTLDS
                     VLYLLELGVNPDDTLLKECADLIFSTWREDGRFKLYPNGGIYPCHTANAANVLCHMGY
                     ASDIRMQKTFQHFLDTQYTDGGWRCNKFSFGRGPETEYSNPLPTLNILNAFRFSNYLN
                     KESKLDKAVDFLLDHWTIKKPLGPCHYGIGTLFMQVEYPFRNYNLFLYVYVLSFYNRA
                     KKDKRFLEALKILESKMIGNKIVVERVVPKLSKLSFCKKGESSEIATTHYYEILKNLE
                     K"
     gene            complement(1733..2521)
                     /locus_tag="PC366_000124"
     CDS             complement(1733..2521)
                     /locus_tag="PC366_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575688.1"
                     /translation="MCILELIKFELKKIELKHVLIFVIISILCIFITGILDYNELIFY
                     NDVPIMDTYSIAGWLGIIKISDVFIPIMSAITIIYVFSKDYLGNINEILTLYNKKKYN
                     QFIVFRWCVILAIYTVLLLISITIVYTFTSVKGFNIDKIDFVYSVKPIDVFLKTFPTL
                     LWYTTFPLMILTLTKNRFTTIAILITYTFADIFFILHMYPFVSMINVNGFYIQKMFYM
                     PNNIDVRFNELKNYFFINRGSLVVISIIIVFYIARKSTVLKKSK"
     gene            complement(2522..3394)
                     /locus_tag="PC366_000125"
     CDS             complement(2522..3394)
                     /locus_tag="PC366_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2575689.1"
                     /translation="MINKLEIRNLNFNYKNKKALDNINLTLTDGVVALLGPNGAGKST
                     LMRLLVTLYETSIGEIELNNIKYSKNNEKIKANVGYIPQDFDMYNNINGQEYLEFVAK
                     MRGVSKNDLKKHIQKVVSKVNLDKFINNKIGTYSGGVKRRLGIAQALIGDSKLIVMDE
                     PTVGLDPEQRNEFRRLLPEISKNSIVLISTHIVEDIQFNCDKLIILNQGKILYDGTIN
                     KFIDMVEVYSVVVSNDEFEYLERNIDIIDYRRVKDGVQVKYIGKNTEKLKDSLRIDTT
                     LQDAYINFLHKELK"
     gene            complement(3409..5187)
                     /locus_tag="PC366_000126"
     CDS             complement(3409..5187)
                     /locus_tag="PC366_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575690.1"
                     /translation="MNLLNIVESIVSCIKGLARRGINMSSIKVISDFITKIIRKNILF
                     AITVIIINYHLIQRWTHISNRGISFNDYLSLSVYTCMTISILTMLNVIFYMRKSYDTV
                     KILCRNNFDYFLGISVAVTRNNFIFCCIPIIYAIAYSSLIRTLSIVTIKSTIFILVFE
                     WFLPLTILSIVISFISVIINNLILKITLSSVFLYLTSTKMLDRVIDIKEPFFKALFKS
                     LNIFEDQSYAYYSDFVGKVNNSAYVIDKIIPTLFAITLIIVAYLILNDIRKKQIKSLI
                     VIVVYSILFIGLNYISIDMSTYRDEERSYGEYLKKSNISDIKIKSHDMKIDFKSKSNI
                     KDRIVLLNTSNEELTNINMILDEIFDIKYIKVNSENIKFNKKKDLIEVNLKESLEPND
                     EVTLDIEYEGYINVLTSWNQNKYIATKDDIMLPPGSLAWYPKVNQSSCMAYKINLSSK
                     NNVYSNLPLLNKTSNFLKKDYIFEGKSNDIAIYAGEFKEEVKDDIKIIYPSDSNVNMD
                     IEEKIKFLIETRNEILGDSKASVDAKKYVDEVDNVMESIKRKKINMILVADLPSNEFL
                     YEDSKGEKISITIYHWLSGNILIIDK"
     gene            complement(5264..5845)
                     /locus_tag="PC366_000127"
     CDS             complement(5264..5845)
                     /locus_tag="PC366_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HDF2575691.1"
                     /translation="MFKRLSYKFANILVNNEIVESEDFEIYRYGFETLIYFIVNISVA
                     LFIGIIFDRFIHTVIFLSCYCTLRQFTGGYHARNYKECTLTFAVIYLITIFSANNIDI
                     NKYKYLLVLLMIISILTIYKLAPLEHRNKPLSESEKKHYRKTVQKILFVIICLIILCK
                     ILNIFQQYVIYAIISIYWIAILIYIGMKVNNDQ"
     gene            complement(5904..6044)
                     /locus_tag="PC366_000128"
     CDS             complement(5904..6044)
                     /locus_tag="PC366_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HDF2575692.1"
                     /translation="MKKIALNLLKNISALSFGIAVLSANSASSWVAHQAKEPQALQKL
                     KK"
     gene            complement(6056..7372)
                     /locus_tag="PC366_000129"
     CDS             complement(6056..7372)
                     /locus_tag="PC366_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2575693.1"
                     /translation="MLTNLSIGFWNIINLVSGTIDWIIFFLVIHLVGKRKISNIRYIF
                     TTIIIFIFMAYINVVKVFPNIKILLCMVIGISFYITSYEDKIYKSIIVSLLFWLGLMI
                     AEGSAVGLVVFINKLNNINITQHENLFRIQAIIMSKVFLFIGFILFKYFKLSLDFKPK
                     DMILIGIPILSNIVSLLLIFEYNLRVNTITTENLFIFIFAILLILSSSIILLIVIGKI
                     VQDDKLNLEYELINERIKTNYRNYENINEVHDRLKYVYHDLKNHMICIKNYDTKEEII
                     SYIDNLEFQISEFEHFKNTGNKTLDLILAEKISICKKYDIQIEDNINISKLNFIENND
                     ICSIFANSLDNAIEACMDINNELEKRIEVKATYINKFAIIKFINTKVNDIKLIDKRIQ
                     TSKDDDKIHGIGLASIKYIVNKYGGETIVNYSDNEFILKIMIPIKS"
     gene            complement(7366..8076)
                     /locus_tag="PC366_000130"
     CDS             complement(7366..8076)
                     /locus_tag="PC366_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2575694.1"
                     /translation="MISIGICDDELHYRIKIKDILSEILSSYPINYNIYEFSSGEELL
                     NNYPKDLDILIMDIQMKTINGMDTARKIREFDHKLEIIFVTSFVEFMQEGYEVKAYRY
                     ILKPINKEKISKSVLPCINEMMKKRNNYLTINVKNYVDRIKIDSITYIETDRPNILIY
                     THDDMYITKMSISKIEKILNEYGFFRCHNSYIVNLKLVESMSGSTVIVDGKSIPISKY
                     RVKGLKLAITNILGDIVC"
     gene            complement(8514..9089)
                     /locus_tag="PC366_000131"
     CDS             complement(8514..9089)
                     /locus_tag="PC366_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HDF2575695.1"
                     /translation="MKKITWEVEYISQLPVIRYCKKCGKKTEYICSGLFRVNAQHKYL
                     DIWLIYKCSNCDSTWNSTIYSRVNPKSLNPETLEQFHTNDYNLAKQYAMNTELLHRNG
                     AEVGIPEYKIVGQEININDLTQVHIISKYPCQLKVSTLLREKLGLSRKVFDEMLDCGI
                     IRSNSGVDLKKGKLNYEIMLDIGKEKQKSSN"
     gene            complement(9382..9660)
                     /locus_tag="PC366_000132"
     CDS             complement(9382..9660)
                     /locus_tag="PC366_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575696.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGEYIYIPRKSNNKKEWGSSTS
                     TREDLSIRNMQIYEDYQVGYDLKYLSEKYYLSLKSIQRIVLQEKRKDS"
     gene            complement(9969..10730)
                     /locus_tag="PC366_000133"
     CDS             complement(9969..10730)
                     /locus_tag="PC366_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HDF2575697.1"
                     /translation="MKNKIETSMNNFVKNYHKSNNITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLENGKTIITYFIPFDESVNNSNIGGFECSEIWARAYIETNMLIS
                     NLNDFLCEELEKMGANSYAIPGSYNFDSEKLVSDWSQRHVAFIAGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDGFNRNKCY
                     EMCMINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            complement(10899..12938)
                     /gene="bclA3"
                     /locus_tag="PC366_000134"
     CDS             complement(10899..12938)
                     /gene="bclA3"
                     /locus_tag="PC366_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HDF2575698.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNNGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGGTGPTGPTGPTGPTGNTGNTGATGLR
                     GPTGATGGTGPTGATGAIGFGVTGPTGPTGATGATGADGVTGPTGPTGATGADGITGP
                     TGATGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGATGPTGAIGATGIGIT
                     GPTGATGATGADGATGVTGPTGPTGATGADGVTGPTGATGATGIGITGPTGATGATGI
                     GITGATGLIGPTGATGATGATGPTGVTGATGAAGLIGPTGATGVTGADGATGATGATG
                     ATGPTGADGLVGPTGATGATGADGLVGPTGPTGATGVGITGATGATGATGPTGADGLV
                     GPTGATGATGADGVAGPTGATGATGNTGADGATGPTGATGPTGADGLVGPTGATGATG
                     LAGATGATGPIGATGPTGADGATGATGATGPTGADGLVGPTGATGATGATGPTGPTGA
                     SAIIPFASGIPLSLTTIAGGLVGTPGFVGFGSSAPGLSIVGGVIDLTNAAGTLTNFAF
                     SMPRDGTITSISAYFSTTAALSLVGSTITITATLYQSTAPNNSFTAVPGATVTLAPPL
                     TGILSVGSISSGIVTGLNIAATAETRFLLVFTATASGLSLVNTVAGYASAGIAIN"
     gene            complement(13005..14081)
                     /locus_tag="PC366_000135"
     CDS             complement(13005..14081)
                     /locus_tag="PC366_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2575699.1"
                     /translation="MIAISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGNPTLSYYRERLFKRSSNHKWVDPIHEVVPLFGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKTLEPRHQFYYSRELYYNARYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPSIQLSVCYDRLGESDKAIYYHEK
                     TKEIKPNDSAVLHNENYFSKFKNS"
     gene            complement(14403..14987)
                     /gene="clpP"
                     /locus_tag="PC366_000136"
     CDS             complement(14403..14987)
                     /gene="clpP"
                     /locus_tag="PC366_000136"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDF2575700.1"
                     /translation="MSLVPHVIEQTGQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSATSGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRCALPNSEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDKILSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            complement(14984..15442)
                     /locus_tag="PC366_000137"
     CDS             complement(14984..15442)
                     /locus_tag="PC366_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2575701.1"
                     /translation="MEIIDYIEENLTENLNLDKIAYIANYSKYHLHRMFTNVVGCTIH
                     QYIQRRRLTEAARQLIFTDKYIIDIAITVGYSTHQSFTLAFRNLYKESPQVYRNKDEF
                     YPIQQRFVLNLNHQIQSEKCISYANMNYKQRRDEINSYLNFNINCEVKVA"
     gene            complement(15665..17080)
                     /locus_tag="PC366_000138"
     CDS             complement(15665..17080)
                     /locus_tag="PC366_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2575702.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILDGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNDTFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRVEISKYL
                     FRTRGIRCNSKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGIKVDDKGMNTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKCATENDYYII
                     EDDYDSEFRYEGQPISSLYELSPNKVIYIGSFSKILSPAIRVGFMLLPDNILESYKTL
                     KMYSDVHTETILQYVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIENILEYDHEIILGYAHLS
                     FDEIEKGVKILSKIIHMNQGT"
     gene            17195..17863
                     /locus_tag="PC366_000139"
     CDS             17195..17863
                     /locus_tag="PC366_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575703.1"
                     /translation="MLEISHKVKEIYPNIKFGVMVINITHSKPNKENFLVLKNSTIKN
                     IIEQHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKMELPLKIELANGSEHFYGIGGKEHILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKHYISSAFPDLKVNS
                     IDIF"
     gene            complement(18039..18557)
                     /locus_tag="PC366_000140"
     CDS             complement(18039..18557)
                     /locus_tag="PC366_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2575704.1"
                     /translation="MNFVELTKKRYSCRNYQDRKVEKEKLEKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGINKLSKAANIYDAPLAILVCGDKDKVWTRPFDGRQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKIPESPERHEKTR
                     VPLSEIVSYETL"
     gene            18709..19032
                     /locus_tag="PC366_000141"
     CDS             18709..19032
                     /locus_tag="PC366_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2575705.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLESL"
     gene            complement(19037..19621)
                     /locus_tag="PC366_000142"
     CDS             complement(19037..19621)
                     /locus_tag="PC366_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HDF2575706.1"
                     /translation="MKVLVFLAKGFETMEFSVFVDVMGWARNDYGHDIDVVTCGFKKQ
                     VMSTFNIQVLVDKTIEEVCVDDYDALAIPGGFEEFGFYDEAYDSSFLNLIREFNSKEK
                     IIASICVAALPVGKSGVLKNRKATTYHLKNGKRQRQLSEFDVNVVNEPIVVDKNIITS
                     YCPETAPHVAFKLLEMLTSREQMDEVKLAMGFKL"
     gene            complement(19670..20125)
                     /locus_tag="PC366_000143"
     CDS             complement(19670..20125)
                     /locus_tag="PC366_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HDF2575707.1"
                     /translation="MDEIDLKIINSLKKNSRASTSEISRQINLSVPAVSERIRKIEQS
                     NLIQKYTIQINREKTKYKLLAFIFINTDLSKSMKEFKKTILEYDTVLECHHISGEYDY
                     LIKVLAEDTSNLEEFISVTLKEIGGIQKANTTIVLSTIKEEFNTIKDIF"
     gene            21008..22546
                     /locus_tag="PC366_000144"
     CDS             21008..22546
                     /locus_tag="PC366_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2575708.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVVPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQKSAISENEQYLIKASDYQEQLIASNFYSIDNEINKIANGLGLDSIGMNRVVEEL
                     SGGQRAKVILAKLLLSNHDVLLLDEPTNFLDKEHVEWLSNYLNTFNGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKSHLREDYIRRYQAQQKKIEKEETFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPSFTGKPNIQFSEIEISAQNALTITNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPRISGDFQFSEQVKIGYYEQDL
                     KWENPDKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLSPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            complement(22818..23531)
                     /locus_tag="PC366_000145"
     CDS             complement(22818..23531)
                     /locus_tag="PC366_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2575709.1"
                     /translation="MDTYFNKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAI
                     SLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGD
                     DYITKPFSPREIAFRVKAQLRRQQYQSIVPSDSAVIKIGDITIDIEGNRVYKDRNEIE
                     LTGREYHLLSYMAQNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSN
                     PKILITVKGLGYKLVNRID"
     gene            complement(23986..25365)
                     /locus_tag="PC366_000146"
     CDS             complement(23986..25365)
                     /locus_tag="PC366_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2575710.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCRSYLFIILVFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTVSGMVFFSKNKELLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLIGEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNILNINGIWLAVPSAEILTLFLTIFCIC
                     KYKNRYKYM"
     gene            complement(25650..26444)
                     /locus_tag="PC366_000147"
     CDS             complement(25650..26444)
                     /locus_tag="PC366_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HDF2575711.1"
                     /translation="MMKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLM
                     FNSIYSHVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYIT
                     KPLDPLFRLTFENINIGSSPLILASILIVLYGISKLNSEITLVMIIIYIFMVLLMTLL
                     FYDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGVFKVLFYLILPYGIMS
                     TIPTQILAGTITINGLIYSILIVFLFTLFMWRFWKLGMRHYKSASS"
     gene            complement(26441..27304)
                     /locus_tag="PC366_000148"
     CDS             complement(26441..27304)
                     /locus_tag="PC366_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HDF2575712.1"
                     /translation="MSIMSNYNEASSNYSMFYKFKQSIRRYYEVAKINFKVQLIWRFD
                     VVVNMVFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLAGIDMSKSTSE
                     EICNRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKIDFAFT
                     SNPVQILISILMIFLGFIFMMKLHFFIGILSFKFLEISFFRMIIENIVEFITGTMIPL
                     VLLPETIVTVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYK
                     RMRTLFDGVGI"
     gene            complement(27282..28277)
                     /locus_tag="PC366_000149"
     CDS             complement(27282..28277)
                     /locus_tag="PC366_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2575713.1"
                     /translation="MSIIELNELTKSYRRFEKKAGFMGSVKSLFNRKYTEKTAISSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAVV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSDYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAIAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEKLFNHFQKYKKITVSFSNETNIVFPKDCKVVEQT
                     NHKTSVIVLKERGNETIKWIFDKYDVKDVMIEEEDIGSIVERIYKKGSDEYYEQL"
     gene            28980..29936
                     /locus_tag="PC366_000150"
     CDS             28980..29936
                     /locus_tag="PC366_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2575714.1"
                     /translation="MENNTIQKQLRDLSKKIWHIYILNPEEENLKFIISLLDNNLALI
                     GTGKHEFYETLEEFIIGLEKDQTESEQIDFEIIDEWYSCTKVTDEAFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVTDDMIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSYGYFYIFDLDNFKQVNDIFGHV
                     RGDEILIQFSNILTKVFVNDAIIGRLGGDEFAVFEYSNQSKENVENKAKKVLELCLES
                     NSCSIGISKLENKSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            complement(30337..30885)
                     /locus_tag="PC366_000151"
     CDS             complement(30337..30885)
                     /locus_tag="PC366_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575715.1"
                     /translation="MEGLGFYAAALSGSSYQRIGFGKLDPIEVIADGDWISYKQAQDT
                     LTVIRNFLNSFDWRNASEMERANRAAKLVTEAKYVDSKYCNIVYGNLVDKRGVCGSFA
                     SSFHLLTRLMGMDSLSILNPSLNHAWNYIQIDGKWYRSDGSEISAFGGALDFDYRKLK
                     DATREMTTYYDAKALSILGFNQ"
     gene            complement(30987..31685)
                     /locus_tag="PC366_000152"
     CDS             complement(30987..31685)
                     /locus_tag="PC366_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575716.1"
                     /translation="MKISSQYRSQYSFRHESNINNTRINESMVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKYRQEVYTKKINEAIKNLYKSEIRETTNNFSNIEIGIKNSIIED
                     KNKSTMLDENSTYLNTNDEKESLITKESNEKIEEEILNDEKLEELEQKKDYKEDSNKK
                     EKVSEDLSLVGKTREELENMLKNFINLTQEEIMKLESRIEKLDKDAEEYKQNSKTNIF
                     DKTDEQKKHINVLI"
     gene            complement(32221..33288)
                     /gene="rsgA"
                     /locus_tag="PC366_000153"
     CDS             complement(32221..33288)
                     /gene="rsgA"
                     /locus_tag="PC366_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDF2575717.1"
                     /translation="MNGMKQINLQDYGLNRNFITQSMEYHDLYLARIISQEKNFYQAV
                     CVNGVLFAEVSGKLRFEATIQSDFPTVGDFVMLDRCNNKNGNAIIHHVLHRKSLFVRK
                     AAGKVNEEQVVAANIDIVFLCMSLNKDFNIHRLERYLSLTWESGAIPVVVLTKSDLCD
                     NVHRKLQVVNSIALGVDVVVTSSIEPDGYKQISKYIKSGCTVALLGSSGVGKSSLINC
                     LLGGEFLNTKEIRIDDDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGLDKS
                     FADIEAYFGKCHFRNCTHTSEPGCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKSE
                     YLAKKEKKFKNISKINKTIRR"
     gene            complement(33285..33686)
                     /locus_tag="PC366_000154"
     CDS             complement(33285..33686)
                     /locus_tag="PC366_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HDF2575718.1"
                     /translation="MNYKNRKRAYYQENSCMDNFICKNCGCLVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNS
                     VKLMSIALKPLAQPPFPLERIIEKLEKEETE"
     regulatory      34482..34578
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            34632..34808
                     /locus_tag="PC366_000155"
     CDS             34632..34808
                     /locus_tag="PC366_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575719.1"
                     /translation="MFRDKMDRCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            35218..35856
                     /locus_tag="PC366_000156"
     CDS             35218..35856
                     /locus_tag="PC366_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575720.1"
                     /translation="MSNQIKDFDITNDMFQESIPITTKTILEDMPSNDELNHVFSKGC
                     ERKMKKRKIVLITLLLIGVLLLGSILYNLFLVKAANISMLKESWNFDIPIPNKEIEVF
                     DTQDSINGDGQSYFIQGFSEKNFKKVFNLKGGIVVSKDNINEIEKYIDKFKRDSVNIN
                     KSNKNKIEEDFKKYKLEVKKDDKYIYKRNYENYVVLIIKKDEQKLYSLIWNQ"
     gene            complement(36334..38010)
                     /locus_tag="PC366_000157"
     CDS             complement(36334..38010)
                     /locus_tag="PC366_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2575721.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIDGYSLEAQKSRMKAFALYNDYEIV
                     GEYEDAGKSGKSIEGRVQFTRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDFGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRVQTMEGRIQKAKEGKWNG
                     GFAPYGYQLIDGKLIINEEEAIAIRTIFDQYVNTSIGANGLSKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYRQVEQDDYLVAEGIHEAI
                     IPDELWQAAQVKLKAQAKKYEHVNKGKNMRTHLLSGIVKCPICGAGMFGNKSIKYKKD
                     GTKYKDFYYYGCKHRLMNRGHKCTYNKQIREELLDDAVAEVIIKLVSNPKFASMIQEK
                     INMKVDTSAIENEIDNYQNELRKSHSTKYKLIEEIDNLDVEDKHYKRRKNDLDDRLYR
                     MYDKIEELESQLIEAKAKKETIEVEKLTGDNIYKVLIYFDKLYKVMNDVERRQLIEAL
                     ISEIQIYEEKQPNGQWLKSITFKLPIIDEDLNISLENDEQVETVAKIIKQ"
     gene            complement(38111..38263)
                     /locus_tag="PC366_000158"
     CDS             complement(38111..38263)
                     /locus_tag="PC366_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575722.1"
                     /translation="MDNDWNGLADLIANLITKYAGVLDLENLPNPTPVKNTEDKNKFD
                     IAKSTD"
     gene            complement(38752..39162)
                     /locus_tag="PC366_000159"
     CDS             complement(38752..39162)
                     /locus_tag="PC366_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004634151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2575723.1"
                     /translation="MAKEYYLYIRGQKVKVSEDIYIVYWREKEHEKYLEQVDRKNHLL
                     FFSALDHDGHFTDNIVDESVDVEKIVETQMMIEAVRSAITRLNAEERDIIERLYFNDE
                     TVRSVAKLKSITHPALIKRRNKILEKLKKFIEEL"
     gene            complement(39686..41005)
                     /locus_tag="PC366_000160"
     CDS             complement(39686..41005)
                     /locus_tag="PC366_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2575724.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLVFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLELYSKSSEIKAFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKTRLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKALQDEEFFIFKIKIFS"
     gene            complement(41002..41655)
                     /locus_tag="PC366_000161"
     CDS             complement(41002..41655)
                     /locus_tag="PC366_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2575725.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYNDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            complement(41753..43129)
                     /locus_tag="PC366_000162"
     CDS             complement(41753..43129)
                     /locus_tag="PC366_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2575726.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKIFQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSSKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDVHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFVGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIARQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFIIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(43129..43785)
                     /locus_tag="PC366_000163"
     CDS             complement(43129..43785)
                     /locus_tag="PC366_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2575727.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQKKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(43795..45072)
                     /locus_tag="PC366_000164"
     CDS             complement(43795..45072)
                     /locus_tag="PC366_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2575728.1"
                     /translation="MIKNAIAYITRKRNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIGENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNKSENNKIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKHIIKIMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMLNITTLGQ
                     SYLILISIIVLSVVFASSLILIKKPKEILSKIS"
     gene            complement(45091..45981)
                     /locus_tag="PC366_000165"
     CDS             complement(45091..45981)
                     /locus_tag="PC366_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2575729.1"
                     /translation="MDRIKNIINGSTKKDKYKIRDRFRHLFQSVWFLITNSYFEGFKT
                     GKIYGGNLKKICVPGMNCYSCPGAKGSCPIGSLQAVIGNSKYKISYYIVGILFFIGAL
                     VGRFVCGWLCPFGLIQDLLHKIPFFKKVETFKFDKHLRKLKYIILLVFVIILPLFLVD
                     ILGQGSPYFCKLICPIGMLEGGLPLVLLNKSMRNAIGFLYYWKGIILIVTLLLSIIIY
                     RPFCKYICPLGAIYSIFNPISIFRYRLDKDKCINCGKCKKVCQMNIDPVENCNHLECI
                     RCGRCKNACPVDAISYGVRK"
     gene            complement(45974..46069)
                     /locus_tag="PC366_000166"
     CDS             complement(45974..46069)
                     /locus_tag="PC366_000166"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDF2575730.1"
                     /translation="MAMIYYGHSNGETKVVLDKAIRICMECIGIG"
     gene            complement(46148..47305)
                     /locus_tag="PC366_000167"
     CDS             complement(46148..47305)
                     /locus_tag="PC366_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HDF2575731.1"
                     /translation="MKKIVSRGACLLLTLCLSLSTVGCKKSNESNKIKEGQSISSEEA
                     GMSTNEKDKNETFKPSDYTLKTKKEYVYEYLGLKFKLSDKFKKYMDDKKIAMLDDQSP
                     IDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELERIGTIGIFEKNTSEEKISK
                     ITKCDTHTKIGVSSDGKYDCYLSTNSGAESNLLDELKRTEIQIIDKKERPKNGFVLSE
                     KTDLENTEAFNKESVKDLRKLSTKDINGKDFTSKDFEKYDLTMVNVFATWCTACVKEI
                     PDLVEVQNEMKSKGVNIVGVVTDTVDDNGENKEAIEKSKLIHEKTKASYPFLMPDKTN
                     FNGRLNGIQAMPETFFVDSNGNIVGDTYSGAKSSKEWKQVIEKELEKIKNK"
     gene            47639..47989
                     /gene="mobC"
                     /locus_tag="PC366_000168"
     CDS             47639..47989
                     /gene="mobC"
                     /locus_tag="PC366_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HDF2575732.1"
                     /translation="MANRIRNERLEIKLTEEEKALFEEKRKLARCRNMSHFIRKCVLE
                     KEIYQVDLEPFRDLQGLLSNATSNINQIAKRVNSTGIIYKDDINDMKKQIEYFSKELW
                     QIHSLLLNRTSGGD"
     gene            47995..49326
                     /locus_tag="PC366_000169"
     CDS             47995..49326
                     /locus_tag="PC366_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDF2575733.1"
                     /translation="MAITKIHPIKSTLNLAISYIVNGKKTDEQILVSTHKCHQETAHT
                     QFLRTRNDVGTNGTVLARHLIQSFLPGEASPKMAHQIGLELCKKILKDEYEFVLSTHI
                     DKGHIHNHIIFNNVNMVTGKCYQSNKKSYHKIRYQSDKLCKENNLSVIDEFYESYKRK
                     YKTNGKSWYENEQSKRGTSWKSRLQFDIDRLIKQSKYWEEFLKKMAELGYEIKYGKHI
                     AFKPKDKTRFTRAKTIGEDYTEERLKERITENQSITTPPVKRRIGNIINMNANAKVKE
                     SKGYEYWATKHNLNTMAESVIFIREHGINSIKQLDKYIQKSAEERQDLQDKMKEIDKD
                     MQLLSDTMEQVHTVKKYRAYYKEYKANPSDKAFFEEHKAEITHYEIALSKLKKSYSKL
                     PNSKDILDKLNKLQEKKNTLIQEYSSTKSTMDELYQIRKNYGIYMGKEMER"
     gene            complement(49362..50168)
                     /locus_tag="PC366_000170"
     CDS             complement(49362..50168)
                     /locus_tag="PC366_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009354872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PQQ-like beta-propeller repeat protein"
                     /protein_id="HDF2575734.1"
                     /translation="MEISKKELRKISRKFRILASNVMNSYYGEQNANLEEMINYIEQT
                     LLIKEYLHSLEYDVDGLDDLLNTISNSYGRKVLNLGNDSNKRTYLLYRAFSFITGNNL
                     PTYTFGWYYAGSNKYQDMAKAFGDRMVYPFVLEVENYMKDISTDMGYDENNALYNINV
                     NSSGVQVNIAEHGSTINADQENKFNTEEVIKAINNVEDLIKGMEDDNSKSILNQNLDN
                     IKNEIKQKHPKKEVLTTCLKSMHFITTSVALIPDLALGIKMLASLIGISI"
     gene            complement(50158..50619)
                     /locus_tag="PC366_000171"
     CDS             complement(50158..50619)
                     /locus_tag="PC366_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HDF2575735.1"
                     /translation="MANDIKFEISVPADEEGYVQLKCPSCSEKFMLTVEDIEAESTID
                     IWCPNCGLTHENYLDDDIYELAERIVENQVAEMLNDFSKNLEKSFRNSKSIKFKRGKE
                     IKKEAELPIGRKTGDYEEKKYLCCGKTARISSIKKLEGSYCPFCGEMIDGD"
     gene            complement(50647..51714)
                     /locus_tag="PC366_000172"
     CDS             complement(50647..51714)
                     /locus_tag="PC366_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009354804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HDF2575736.1"
                     /translation="MSGKLYIAAAGSGKTRKIIEDSLNTHKKILILTYTITNEQQIIS
                     RIKNKVGVIPNNITVSTWFSFLLKDGIRPYQGSRFKERIEGIIFVNGQNNTYVKKTSN
                     KYFAKDNRVYTDKLSECVVELNDKCNGKVFERISGMYDCIYVDEVQDMVGYDLEILKC
                     LIASRIEVIMVGDPRQCTYSTHSSKKYKKYSCGKIDEFLKNECRKLDVRIDETTLNCT
                     YRNNDIICKFANSLYPERTSTNFVRRAEDESDGVMIIDKADVEKYLQKFNAMQLRENK
                     RTSVNNEYPYYNFGESKGLEFQRVLIYPTQPMWDWIINNNTSLKEQSKARLYVAVTRA
                     ENSVVIVRKDARPCSLPVVKL"
     gene            complement(51711..53333)
                     /locus_tag="PC366_000173"
     CDS             complement(51711..53333)
                     /locus_tag="PC366_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2575737.1"
                     /translation="MSIRKLKIKNFKCFSDWFIVDFENGINILVGNNGTGKSTILEAI
                     NLVLTGTYHGKNIRNELTQYLFNKNIVENYIREVNEGVNVEPPKIIIEAYFDAEMPSF
                     LGDGNSEKTKDTPGICLSISFDEKYSNEYKMLCKNKITSLPIEYYEVSWMSFARENIT
                     ARSIPIKSAMIDTTSYTPTSGSDIYISRIVKNLLDDNEIINISQAHRLMKEQFSRDEN
                     IANINRKLTETSNNELTISVDFGTKTSWESSLVTQLNEIPYNNIGKGTQCIVKTQLAL
                     SDHKIENKQIVLLEEPECHLSYSNLNILLDKVNESVKEKQIIVTTHSSFVSNKLGLEN
                     LILLNRGKTLRLGDLSNETNLFFKRIAGYDTLRLLLSNKAILVEGDSDELIVQRAYMD
                     SHNGKLPINDGIDIISVGISFLRFLEIAKLLELRVSVITDNDGNIDALNRKYSDYLGD
                     NCCENINIYFDDSTHEYNGSLENYNYNTLEPCIYRSNSMSILNEILNKSYEDPDDLLK
                     YMKGHKTEVALKIFESDKAIEFPQYIKEGILI"
     gene            complement(53536..53766)
                     /locus_tag="PC366_000174"
     CDS             complement(53536..53766)
                     /locus_tag="PC366_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2575738.1"
                     /translation="MRVFSYKRLFKKLIDLDMTNNELMEKAKVSKSTFYKMKNGQNVT
                     TDVLLRICNALDCDIEDIMECVIIEDVRRMGV"
     gene            complement(53906..54565)
                     /locus_tag="PC366_000175"
     CDS             complement(53906..54565)
                     /locus_tag="PC366_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006627214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2575739.1"
                     /translation="MDYKTMRDRVEDMLSDNHKDFVKAIISMEKGINDESALDKLYDA
                     YMDNDSLNLLHEEFDYMIEDLRGQGQIKDLLYVREEKDNLINIVGNIVGEVDVIEREN
                     KNGETFKVANFSVVSKDDEGNKLYHNCSVYGEKSDIPKDFKQGDFVKLFGQIRTSIDD
                     NGKEHSNIRILSSKLLKAKEQMKGQEEKKESILGAIKKYQAEDKEKPKEKKEASKEAE
                     R"
     gene            complement(54608..63337)
                     /locus_tag="PC366_000176"
     CDS             complement(54608..63337)
                     /locus_tag="PC366_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDF2575740.1"
                     /translation="MRINDFHNILELIKQDVLYNEAEYLKLLKVVGNNQRYDFRSQLS
                     IYDKNPEATACAKFDYWRERFNRTVMRGQKGIPILEDYGTYKKVDYIFDISQTVSKNR
                     DVNEVNLWRFDKEAHQDVLKEMIKSEGYEESESTLENIFSLSRLYGDEKIDTLMNELR
                     VADEDRISFTKFVRDSVSYAVASRFKLDYPMDYELLRENFQRFDSISLMSLGESVSDI
                     SGKIIDETIQKSKELELQKEVLIGKEAGYNKIKEELEEVEENVFRRDDQERNENERVL
                     RNGEYGRDNRKNQGEYAKQLGGTDGLYKEVSESDLRSDEAELPFTERGAEPLRDAFGS
                     IQGEEADRTPDGYSETGSRVYESREAKVDSSLEDRGREQSAVWGDDFSSQRNDHQGSS
                     GDLKDNTDKGIIEAEKASFSLPENSYGQISLTIPLTEKDIDTVLINGGNHDGGRLPVI
                     AEFSKGKSIEELGEYLKDTFKGGNGFYIDEREVSSWYSDKGIHLAYGTSAREDNTQIL
                     SWSDAASRINELLDRGEFATNVELLEAQDYERDRISESLWYLTHDLSEEGIEQGYFNS
                     FERGGGFPQETKRLSEALKNPEYLKETIKEYSRFLEGYKESRNVLRYHYHKVDSLYQK
                     LQELELQRKEYSTNLTELPKVKLFITEDEVLESLSRGSGVDRGKERITKFFKENHTLQ
                     EKANFLKDEYGIGGHSHVVSGAMGSDEWHDAKGFKLQKNDCNDVFLTWTSVAKHIDEL
                     LSKKLYFEEKETESTAEIEEVKEPQYYSKNDPGNLMPDEILERVPEIYAQEDVDLADK
                     QVHAAYIIPFRSNWTWYMTEYDRESGDAFGLVLGIEPEWGYFNLEELKELNAQRLILE
                     DFPKTFRELKDIELIKQMDEQELQFVFNGELSFEDKVELEAPEETEEATKRGTVQATL
                     FDYLKEREEVELNEKEDSLLEEFAVKAGDTVYFNHEEYKVREISKNEITGRYDLWLDP
                     VRSGNHQIPIVDFTDNEDLLNKISLERPNFIVGDEVKYKDKNHTITRFDDMRKNLNTV
                     TVKDNTEYFGGMITSFDVIPYRLESDLERVFENLTYKQPEQTTEETQIRKAEAHNFKI
                     TEETLPEKLSPSERLNNNLEAISMLNRVESGQRELDSTAQEVLARYVGWGGLSEVFDE
                     SKEGQWKEARAFLNENLSHAEYEAARESTLTSFYTPKTVIDGIYKTLSDMGFKQGNIL
                     EPSMGIGNFIGNIPDEMNKSKFYGIELDSVSGRIGKLLYPESEVQIKGLEETSFSNNF
                     FDAVIGNIPFGEYKVNDREYNKNNFLIHDYFFAKSIDKVRNGGIIAFITSSGTMDKKD
                     ESVRRYLAARAEFLGAIRLPNDTFKGIAGTEVTSDIIFLKKRDSIRERDEDWIHLAED
                     ENGLTYNKYFVDHPEQVLGTMREVSGRFGNTLACLPKENADLKELLTKASEEISKGST
                     YEEIELLDDEITSIPATDDVKNFSYTVIDDEVYYRENSLFIKKEITDKNKEKIKDYLE
                     LNTALKDVIYKQKEDYSDDEVKKAQEKLNEVYDNFSKKHGFINNLSNTRALKEDSNFP
                     LVSSIEILDEEENVKAKGDIFSKRTITKAKVIDHVDTSLEALVLSVSEKGYVDFEYME
                     SLTGKDRPTLIEELRGEIYLNIREEQNFYRPLSFNLEDGDLPFACANGSNSYKYGYVT
                     KDEYLSGNIRDKIAIVDSYLAKLRQTERELPHLGFVENGKEKELISYEMNRLEYQKAE
                     LTKVLPKELEASEINVRLGATWIPIKDIEKFIFETLKTPGYARWDIKVKFSNITSEWN
                     VEGKSRDKGNDLAEMTFGTSRVNAYKLIEDALNLKETKVFDQIINPDGSKTSVLNKKE
                     TMLAGQKQELLKEEFKNWIFNDQERRNRLVKLYNERFNSIRNREYDGSNLSFEGMNTE
                     IDLRPHQRNAIARSLYGGNTLLAHVVGSGKTFEMVASAMESKRLGMCSKSLFVVPNHL
                     TGQIGREFMQLYPSANIMVADKKDFEPKNRKRFIGKIATGEYDAVVIGHTQFEKIPMS
                     KEYQEKHIQDQINEIVNYVEEYKHDRNQNFTVKQLEKTKKKLETRLEKLNDDFKKDDV
                     ITFEELGVDMLFVDEAHNYKNLYLYTKMRNVAGIGQSEAFKSSDMFMKCRYMDEMTGG
                     KGIVFATGTPVSNSMTELYTMQRYLQYESLKKNHLEHFDSWASTFGETQSSFELSPEG
                     TGYRVKTRFSKFYNLPELMSMFKEVADIQTADMLNLPTPEANYEVIKTEPSEEQKEIL
                     KSLSERADDVRNRVVEPDVDNMLKITNDGKKLALDQRLINPLLPDNPDSKVNVCVKNV
                     FAIWDKTKENRSTQLLFSDMSTPKGDGEFNIYDDIREKLVAMGIPKEEIAFIHEANSD
                     KQKDELFAKVRKGEVRILMGSTQKMGAGTNVQNKLIALHDLDVPWRPADLEQRAGRIV
                     RQGNENEKVNIYRYVTENTFDAYLWQTIENKQKFISQIMTSKTPVRVAEDVDESSLNY
                     AEIKALATGDPKIKEKMDLDNEVTKLKMLEANYKSNRYRLEDKVAKNYPEEIARTEKL
                     IEAVKKDISNVEPKAEGEEKFTSITIAGEKITDKKLAGERLLEAISKVKINESKVIGK
                     YRNMDLEVSYNFFTNSHNFSLNGVAKHLGELGTSADGNITRLDNALEKMPEKLNMLEE
                     KLISTKEQLENAKEELKKPFEKADELKTKVLRLAELNKLLDMGEVEEKKNDNPLVEDV
                     KRAIIDFCNREYEENHSYDEFHTLYPDLKHIGIAYTNTPDERHGIQYELNLEEKTWTQ
                     YIDDTPIKTESFDYENKGENEALRNMKNEIELSTFSDLVYVDSEDLRVATGLDIDDEG
                     NFYDPFAKDLDNDGIPDRYDSDFKDSDYFESTYDVEDNLHSKEETTQKSDDKPSILGQ
                     IRAYQEESKTEEKQKIKEQEFLR"
     gene            complement(63420..64223)
                     /locus_tag="PC366_000177"
     CDS             complement(63420..64223)
                     /locus_tag="PC366_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004804477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KilA-N domain-containing protein"
                     /protein_id="HDF2575741.1"
                     /translation="MSKINVEGSEISIIAIDNRDYISLTDMVRNIENGSALIEKWLRN
                     KNTIEFLGIWEEMYNTNFNSPEFEGIKNEAGFNRFILSVKQWVEKTNSIGIVARAGRY
                     GGTYAHKDIAFEFASWVSPYFKLYLIKEFERLKEEEQKKLGWDIKRNLAKINYRIHTD
                     AIKNKLVPDKLSKEKINFIYASEADILNVSLFGITAKEWRDENPDLKGNIRDYADISQ
                     LVCLSNLENLNAVFINEGMSQSERLEKLNAIAIEQMKILSESESIKKLK"
     gene            complement(64308..66014)
                     /locus_tag="PC366_000178"
     CDS             complement(64308..66014)
                     /locus_tag="PC366_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HDF2575742.1"
                     /translation="MKLVIAEKPSVAISIAKVIGANKKKDGYYEGNGYRVSWCVGHLI
                     QMANPDAYDEKYAKWNMADLPIIPSDYKYEVAKATKKQFNILKKLMNDKEVDTVINAC
                     DAGREGESIFRLVYNQVNCKKKMKRLWISSMEDSAIKEGFDNLTDGKDYDNLFESAQA
                     RAIADWLVGMNISRLYSCLYQQNYSVGRVQTPTLAMIVKRDDEIANYQKEKYYTVELS
                     MNGFTLSTDRIDDEVAAEQLISLVGDKIEITDVIQKEKITKPDLPFDLTTLQRECNKY
                     FGYSAKQTLDYTQSLYEKKLITYPRTDSRCLTEDMIVSTVNNILGKNDFDTERIKVVF
                     NSKKVTDHHAIIPTISSVKEDVSELPLSEAKVYFLISDKFHASVGYPLIENTTKIVAS
                     FDGFEFTSSGKVIKDEGFSKYLKEYKSKKSEDAVLPDVSVGDVLSVENKEVKEKFTQP
                     PKHFTEDTLLKSMEIAGNDALEKGVEVERKGLGTPATRAGIIENLIFKRFVERDKKNL
                     IATHKGISLVTIVADTFKSAETTAKWEMELSDIAQGKSSKKEFLDAIENEIKEAVLTY
                     RK"
     gene            complement(66109..67650)
                     /locus_tag="PC366_000179"
     CDS             complement(66109..67650)
                     /locus_tag="PC366_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HDF2575743.1"
                     /translation="MKTSLKKNNKFWTVALAVIVSISCILGLWTVVYAQEQKSEAPTK
                     NEAVQTEVEVNVRYIFEDEKVFKEEKIKAEKGQLIDSGDLPMLPDDMKFIDEFLFYEV
                     KGDGKDEIIRKVAKMEVKDKETQTEEEKPKQDECTQTEDKGTQTELSKDDISKIEKEA
                     KELQDKLDKLNCELKDKDKLSDKQKNKIKDLEDEIDSLKEKMKKDKGNKDLSEDMKKE
                     IDKLTEKVKELEKKATETNKAPVTSQSVTPISPISGIKTSSGISPQTPQTSVSSTGKG
                     SSDSVSSGNTTKDTGKGKTEVKEKEKEVRYPNKLTAKAPANNSQDSSMGSASKSVNTN
                     KGVASSPSKARASVTENKDNANKEYPIHHGDSSDNKETDQYSADARQFITFQTKNGKT
                     FHLIINHDEDSENVMLLTEVSEDDLLNMVEKKEAPKQEVVKEEPVKEEVKPEKKDEKS
                     NLGTYIILLLVVGGALGAGYYFKVVKKKEDKELEALEEEDDDFFSESESEEEINDADE
                     VEDEE"
     gene            complement(67625..67864)
                     /locus_tag="PC366_000180"
     CDS             complement(67625..67864)
                     /locus_tag="PC366_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2575744.1"
                     /translation="MKKELTTVKNRIKKLKDKKALIDEELEPLFIREEELENEEIIAI
                     CRKNNITISDLIAKVNRQKAEMKKEKTNENQFEKE"
     gene            complement(67876..70008)
                     /locus_tag="PC366_000181"
     CDS             complement(67876..70008)
                     /locus_tag="PC366_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDF2575745.1"
                     /translation="MGKKLKKDFKERHKASLEREMFHSKTDTIPEESKLKHNDDYRGK
                     IVHEKERFQDKVHEKTSKVSADNEKSYGTSKRNEKYRTSDKGDVNSAIETGRSDYITE
                     VKDGKIYDPLGKDLDNDGIIDRYDNDFRDSNYFESTYDVEDNLSHKEKSLENSFKNHK
                     TQKSRYKRKNYSESLYTRKKDDAPKGNKADDKKAGKDAVSGKVYSSLSKDQKKKLKKD
                     MVKVSALSGLAKGSETVRDYLSHGSDENQGVEAGEKTADTSSKLIHGIKKYSDKKRAK
                     RGYDLTNKDYKIRKRKSKLEFRDAKKELKKTDEYKRASAYKRFQKKNQVKAAISRENK
                     SRLRDRIKEGLIGTLKSSKDMIIRKAKGLMLIFIGIIILGTFVINFAGTGMTGFMNST
                     SSVLTTSYLSKPNVLSEINQKFSDMEGELQSEVDYVKENYPGYDEYILNNTEYIGHNV
                     HELLSYITSRCGEVKSVSEVESILKELFESMYDLEYREEIEIRYRTVTETYTDEDGNE
                     YTESHEEPYEYKKLIVTLHKKEMDSIIRKVFANYPDNLKHYEALFLAQGNMREAFGNS
                     DLISANGGIGGGKEYEASTEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGYIGG
                     NACDMYRNYTFTSDRSKLKVGMLVAVESSSSGSSAGLTYGHVGIYIGDGKVIDNIGRI
                     RVTTLDDWIATFCKHHPVGFGFPPNVKK"
     gene            complement(70012..72441)
                     /locus_tag="PC366_000182"
     CDS             complement(70012..72441)
                     /locus_tag="PC366_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2575746.1"
                     /translation="MNKKRKIQQIKLMQNEKALRSQKRDLKKSNCKSKKDKGGILDLI
                     FKKEPKRYTVEDTIPYLRLLKSGICQLDEKHFSKSIAFQDINYQLALDEDRDLIFNQF
                     ANFLNSFDPSISIEFSYINQLGRNEEMKSAIQIPDKKDGFDDIRFEFREMLKSQIVKG
                     NNGLKKSKYVTFTVEADNLEQATSKLERLEIDILSSLKSMGVRAESLNGEERLKILHD
                     VLNPNKTFKFSYKDLKKRESTKTYIVPDEFNFTPSRYFKFGKFIGATSHFQILASELS
                     DRMLSEFLDIDDNINISFHIRAIDQSEAIKMVKRKNTDIDKMKIEENKKAVRSGYDMD
                     ILPSDLITYGEDVKSLLKDLQTRDERMFVVSIVFMNFARTVQKLDNTIAQISSIANKH
                     NCKLKRLDHSQEQGLVSVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSSNSLYY
                     GLNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILVTDDDVIICDPEG
                     EYGNLVRQFKGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGS
                     GLTAEEKSVIDRCLPKIYEKYFEHPTPDNMPILQDLYDMLKGQEEKVGKKLATEMEIY
                     VSGSLNVFNHRSNVDLNKKLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATR
                     YYIDEFHLLLKDEQTASYSVEIWKRFRKWGGIPTGITQNVKDLLMSKEIENIFDNTDF
                     VLMLNQASGDREILARKLKISLPQLRYVTNSNEGEGLLFFGNTIVPFIDKFPKDTILY
                     QKMTTKPEEVR"
     gene            complement(72353..72742)
                     /locus_tag="PC366_000183"
     CDS             complement(72353..72742)
                     /locus_tag="PC366_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HDF2575747.1"
                     /translation="MAYVPIPKDLNRVKTKVAFNLTKRQLIGFTLAGLVGIPVYLFMR
                     KFVPNDIAVIFLIVSTLPIFFITLFEKDGLTFEKYFKYIYLHKFYQPQKRVRKEVYLE
                     QEKKNSANKTHAKRKGIEKSKAGLKEK"
     gene            complement(72746..73006)
                     /locus_tag="PC366_000184"
     CDS             complement(72746..73006)
                     /locus_tag="PC366_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2575748.1"
                     /translation="MNKRKTVFIVVIGAGIMAIIDRIRLHNKVEELEEKTEDIGRCHN
                     DFYLIQQRYNKNTDEQLATIQEEIGSVYEHFEELSKGKEDGR"
     gene            complement(73024..73887)
                     /locus_tag="PC366_000185"
     CDS             complement(73024..73887)
                     /locus_tag="PC366_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575749.1"
                     /translation="MFGIFDKIEEFFKELLLGGIQANLESMFLDINDKVGAVATDVGK
                     TPMGWNGDVFAFIKSINDSVIIPIAGLIITAVLCIELINMVMQKNNMHDTDTFEFFKY
                     IIKMWIAVWLVSHAFEFSMAVFDVAQHMVNKAAGVINTSAVISGDQIVKMVDGLKDKG
                     LGELVMILFETSLIKVAIQVISIVIMLVVYGRMFEIYVYSSISAIPFATMGNKEWGQI
                     GTNYIKGLFAIGLQGLFLMVCLGIYAVLVKTIQITDIHTSTFTILGYAVLLGLMMLKS
                     GTLAKSVLNAH"
     gene            complement(73907..74122)
                     /locus_tag="PC366_000186"
     CDS             complement(73907..74122)
                     /locus_tag="PC366_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HDF2575750.1"
                     /translation="MEFFAQAVNVLKILVMAVGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQLMAGGGIVLIGLKLIPLLANVLK"
     gene            complement(74126..74437)
                     /locus_tag="PC366_000187"
     CDS             complement(74126..74437)
                     /locus_tag="PC366_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2575751.1"
                     /translation="MKQEMININANLVAEPTFSSFEKEGEEVEVVNFTLVKKYGKGKE
                     YINCAAYGEKAEKAEDFEKGDLIHVFGYFKKREKEGKTYKNFVVKSYNKIEKKEENEE
                     E"
     gene            complement(74601..74834)
                     /locus_tag="PC366_000188"
                     /pseudo
     CDS             complement(74601..74834)
                     /locus_tag="PC366_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565771.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraG"
     gene            74976..75149
                     /locus_tag="PC366_000189"
     CDS             74976..75149
                     /locus_tag="PC366_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002576203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2575752.1"
                     /translation="MDYMTLKEASEKWGVSSRQINYYCTDGRIPGAVKMAGVWLIPKE
                     AEKPKDRRYNESR"
     gene            75154..75864
                     /locus_tag="PC366_000190"
     CDS             75154..75864
                     /locus_tag="PC366_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002576202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2575753.1"
                     /translation="MLHIAICDDEKDFVQYLTDLLNQYSKETGRDIKITPYYDGMELI
                     EKYDPTIDLIFLDIQMKVVDGLHAAERIRQMDETVGIIFLTTLTQYGLEGYKYHATNY
                     IIKPMKYARLKSEMDKFLERSQKEDTPSLVITNDTGKYKVPLKSIRYVETYNRNLMFH
                     TEQENIICYKSMKEVERELCDKDFVRCHTSYIVNLFYVKGIKKLDIELITGEIIPISQ
                     PKRKEFMERLTDYWGDML"
     gene            complement(76135..76296)
                     /locus_tag="PC366_000191"
                     /pseudo
     CDS             complement(76135..76296)
                     /locus_tag="PC366_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569186.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            76907..77092
                     /locus_tag="PC366_000192"
     CDS             76907..77092
                     /locus_tag="PC366_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2575754.1"
                     /translation="MLKKYWIKCPICNGKTRVQVFHNTVLKDFPLFCPKCKLTHIIDV
                     EKLEIVIKNTEKQTFII"
     gene            77109..78092
                     /locus_tag="PC366_000193"
     CDS             77109..78092
                     /locus_tag="PC366_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004607971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDF2575755.1"
                     /translation="MKRLPKYTPAEVRNDPYGFTYKEMSEVIGENEAKALYEELYKQL
                     PRKKNLSMLVKNICKSSDTEKYVYELKDNKYIETVFIKRRDGGTVCVSTQVGCPVGCI
                     FCESGRNGFVRNLTSSEIVQQIILLRRKVNRIVFMGMGEPLFNYDNLIKAIHILRDRY
                     GLNFPTDGITISTVGPVDQLKKLREEHLKIQLTISLHAATQSARNRIIPHMRIYAIED
                     VVKQALSYSERHNRKIVFAYLLLPGINDRPSDVRQLAKWFRGKKVMINVLQYNPTSNS
                     RIKAPQKREIVAFKHQLEQAGLEVTMRVSHGREINAACGQLANTYNKFKKK"
     gene            78566..79003
                     /locus_tag="PC366_000194"
     CDS             78566..79003
                     /locus_tag="PC366_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003508282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2575756.1"
                     /translation="MELSSSDKERIQHQYDALAKKTLVGEAKSHRRTLAKRAAREVTF
                     SDLSESELAQLFTTDEYESDYFRFQVSGFDVLVKNELLAEALNALPERKRDIILLSYF
                     LDMSDAEIGELLNVVRTTVFRHRKSALAKIKQYLEGKADDEYR"
     gene            78987..79229
                     /locus_tag="PC366_000195"
     CDS             78987..79229
                     /locus_tag="PC366_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2575757.1"
                     /translation="MMNTVRKSENLLPFPVISAAANGDTTAMCAILKHYEGYIAKLCT
                     RTLKDDAGNTYSYVDEEMRNRLQVRLITRTLAFHVG"
     gene            79688..79861
                     /locus_tag="PC366_000196"
     CDS             79688..79861
                     /locus_tag="PC366_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-encoded TnpW family protein"
                     /protein_id="HDF2575758.1"
                     /translation="MDKKQTITTERKIGKITYLVQALPSEKATDTIHKKIEKLIVKDL
                     QKKPGNPGFLASE"
     gene            79939..81612
                     /locus_tag="PC366_000197"
     CDS             79939..81612
                     /locus_tag="PC366_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016289898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2575759.1"
                     /translation="MLQSNKITALYCRLSQEDMQAGESGSIQHQKMILQRYADEHHFL
                     NTKFFVDDGFSGVSFEREGLQAMLQEVEAGRVATVITKDLSRLGRNYLKTGELIEIVF
                     PENGVRYIAINDGVDTAREDNEFTPLRNWFNEFYARDTSKKIRAVKQAQAQKGERVNG
                     EYPYGYIPDPNNRHHLIPDPETAPIVKQVFAMFVSGVRMCEIQKWLAENKVLTIGALR
                     YQRTGQARYQRAMIAPYTWPDKTLYDILARQEYLGHTITAKTHKVSYKSKKTRKNEEE
                     QRYFFPNTHEPLVDEETFELAQKRIATRHRPTKAAEIDIFSGLLFCAGCRHKMYYQQG
                     VNIEPRKFSYSCGAWRNRARTGSECTSHYIRKNVLLDLVLEDMRRVLRYVKEHEQDFI
                     CKATEYGDMEARKALAQQQKELFKAQARMTELDTLFRKLYEDNALGRLTDERFVFLTS
                     GYVDEKKSLAARIDELQQQIATVTERKRDISRFIQIVGKYSDIQELTYENVHEFIDRI
                     LIHELDRETNTRKIEIHYSFVGQVDTEQEPTQVVNHDRRNMVDVKSIAI"
     gene            81636..82091
                     /locus_tag="PC366_000198"
     CDS             81636..82091
                     /locus_tag="PC366_000198"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575760.1"
                     /translation="MKEYTLIIKGEMDFIILSPQVLSSLITQIHNSPERKVVVSIESI
                     MPPKFTDYLLRVINSNRFSNERFRYRYILENPVTKKGMYEILRQQLSRTNTERFPCFQ
                     TIQLTDTFQGNVELDMECNDLFFWACKDTAAKFVYTFPDGREETLVIEY"
     gene            complement(82139..83791)
                     /locus_tag="PC366_000199"
     CDS             complement(82139..83791)
                     /locus_tag="PC366_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008978103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2575761.1"
                     /translation="MSRKKQVYEKITALYCRISLDDGGDNESMSISNQKLMLRDFAEK
                     HGMFQYEYYVDDGYTGRNFNRPSFQRMIADIEAGKIGCVITKDLSRLGRNYIEAGSYI
                     EIFFPKHNVRYIAVTDGVDSLTRQEMDITPFKNILNDMYSRDISKKVLAGRMTRSRQG
                     KFCGGQPPLGLMRDPEDKGHLILDPETAPVIRKIYDMALDGWGCMRIAKQLMDDKIPI
                     TRVKSNTECDVNYYSWGSARISHILRNPFYKGAHLVCRTHQKGIRSNTYDIIPREDWE
                     VIEGCHEAIVTPEEWEQVQDIIDRRPTIMKGNACPFYNLFHGLVYCATCGKSMQVRYE
                     KVGRTGKNRFTGEMREPIDRAYYICQTYNRLGKNACTSHKIEARDLYNLVLKDIQELA
                     AQAMKDADAFYQRLSSRMERRYLVDASQTEKERKRLEDRNQEIDGMFLSLYTDKAKGV
                     LTEQRFMKLTAALEQEQEANQKRLHDLAVMQSRADAQESEVRTFIKEIRRYAAIAELD
                     ESVLNRLISKILIGEVKKVDGQKVQEVRIVYNFVGEIPEIAA"
     gene            complement(83864..84031)
                     /locus_tag="PC366_000200"
     CDS             complement(83864..84031)
                     /locus_tag="PC366_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008978104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575762.1"
                     /translation="MEKSKNQKNKVRFVVVREFSGEKSMREAFEQLIERQTCEHFEEW
                     RHQREMAEKAA"
     gene            complement(84299..85657)
                     /locus_tag="PC366_000201"
     CDS             complement(84299..85657)
                     /locus_tag="PC366_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015559850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence-associated protein E"
                     /protein_id="HDF2575763.1"
                     /translation="MSAAEALAPEQSVDEVREGLSVTEKGQPANTIGNCRTVFSHDPL
                     LRDAIRLNLLTDRVDIVRDLGWRRNTSALTDTDVKYLLLYFEQNYGLTSEKKMTAALS
                     IVANENCYHPIQDVLNGLVWDGTPRIRSCLHHFLGAEVSDYVEEMLKHFLLGAIRRVF
                     SPGSKYEEMLCLVGGQGAGKSSFFRLLAIRDEWFSDDLKKLDDDRVFLKLQGHWIIEM
                     SEMLATSSAKSIEEIRSFISRQKETYRTPYEAQPKDRLRQCVFGGSSNTLDFLPLDRA
                     GNRRFLPIMIYPEKAEVHILEDEDASRAYLLQVWAEAMTIYRSGKYSMKFSKSIQRQL
                     VEVQKDFMPEDTEAGQIQGFLEHYTGSMVCSKQLFKEALGHTYDEPKRWQLHNINEIM
                     NTVVTGWKPFSNPRMFAGYGRQKGWERDVSGNELPGNEDGFVELSEEECRQLELPKEW
                     IA"
     gene            complement(85617..86303)
                     /locus_tag="PC366_000202"
     CDS             complement(85617..86303)
                     /locus_tag="PC366_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDF2575764.1"
                     /translation="MKTGCLFLCLEVRKSNVFEAVKQAVPTRQAAESYGIQLGRNGMT
                     CCPFHDDKHPSMKVDRRFHCFGCQADGDVIDFTARLFGLNKKDAALKLAEDFSVGFDA
                     KGHDPPRRKPGKRKISEELRYRQAEQKCFRVLCDYLHLLERWEKEYAPQTPEEAWNPL
                     FVEALQKKPYTEYLLDILLSGSMEERACVVAEYGKEVRKIEQRISEFTASHPAGRHER
                     SRSFSAGAER"
     gene            complement(86319..87563)
                     /locus_tag="PC366_000203"
     CDS             complement(86319..87563)
                     /locus_tag="PC366_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/arginine repetitive matrix protein 2"
                     /protein_id="HDF2575765.1"
                     /translation="MKLTRHNGRSGKHGTYNPRHNDRRFDVENSEHIDAERARQNVYW
                     DCYRGFTTHEFRENPEQPDFSFEEIERMYYNEHYGGHVEAQNARNEKTRHTERNRTVE
                     DLLKNNKTCPEESIYQIGTMGESVPPDTLFSIVNEFYEEFERRFGSHIHILDWALHLD
                     EGTPHIHERHVFDCDNRYGELCPQQEKALEELGIPLPNPEKPKGRNNNRKQTFDAVCR
                     TILFDIARRHGLHLDQEPSYGGRDYLEKQDYILMKQKEQLAAQEQKLEELTLKIEDVE
                     TLLDDVSDAAYDKAVEVVTDTVRQETHKEDIRLVEESKKWVLSPERKAPKKEREYAAE
                     RLDGVITKIKNAMQHALAKIQRTLMQPEVKQAGKEQVKKKAKESIMDILAKAKINADR
                     DNRERWEREGRIAPTKKNDIEL"
     gene            complement(87991..88296)
                     /locus_tag="PC366_000204"
     CDS             complement(87991..88296)
                     /locus_tag="PC366_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HDF2575766.1"
                     /translation="MRKLSKYEKETIINWNEAENLASVYTFNASLKRRLADFSRKYPL
                     LCRLERSTPEGSVTYVLDKSRLSIRLVPPYSEERKAAASAYAKEHGFQVVGAEEKIA"
     gene            complement(88280..88573)
                     /locus_tag="PC366_000205"
     CDS             complement(88280..88573)
                     /locus_tag="PC366_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575767.1"
                     /translation="MTLSMKEKKILYAYGCPSHHNTVTRLKWLTALTVDPEAKRRMLG
                     LARKVETEVGENWYEDFYHHLRMEMDEYRRLKRSLRVLKSYTDYEEDLYEEAV"
     gene            88939..89787
                     /locus_tag="PC366_000206"
     CDS             88939..89787
                     /locus_tag="PC366_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004845315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2575768.1"
                     /translation="MYAKLTIPERLKDLRVVDKHLTLEQLAEQTGLSKSALGKYETDD
                     YKDISPFAIATLADFYGVSTDYLMGLTENKNHPNIELQSLHLSDDMVELLSSGKINNR
                     LLCELATHPNFRRLMIDMEICIDQIANMRVEQMNLVLEATRQTVMNKYAPGEDDLYMR
                     TLELGQVQESDFYSHVMHDDLDSIVRDIREAHRKDKTTADPQPTLDDVKEKFEQAIGQ
                     GSDTEMLIHEFCDKLQIPFEKISSEDFSAFLRILSLSKQLKSSNNMRGKASPIPPNRK
                     ARRKRK"
     gene            complement(89909..90190)
                     /locus_tag="PC366_000207"
     CDS             complement(89909..90190)
                     /locus_tag="PC366_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575769.1"
                     /translation="MILEEMYNGRFYPCETVVADSPRFKQAVKASAALMDTLSERLSK
                     EDYALVEELREQVAIAQCEENESHFKYGFSAGLLVQQEAHAQVSQKDKE"
     gene            complement(90204..90581)
                     /locus_tag="PC366_000208"
     CDS             complement(90204..90581)
                     /locus_tag="PC366_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HDF2575770.1"
                     /translation="MEHLPKKIHHNGISYTLVGDYYIPDLKLSEEIRPIGRWGRIHKA
                     FLQEHRPGQYNELLLSGKLWTYLADLNEQADDRLACIISQMQAAEGVTEELKARDQLA
                     WVGGMNSIRSRVEEIILSEMIFV"
     gene            complement(90679..92241)
                     /locus_tag="PC366_000209"
                     /pseudo
     CDS             complement(90679..92241)
                     /locus_tag="PC366_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565768.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
     gene            complement(92238..92723)
                     /locus_tag="PC366_000210"
     CDS             complement(92238..92723)
                     /locus_tag="PC366_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HDF2575771.1"
                     /translation="MINEEIARKTLNMEINAGKVTGKVLLNLLKKLMKEAEKFGGLEK
                     LVNANGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKNKETGKNSVF
                     FQAKDMKVMDKAFKHALSKSEKKAERKESIHKNIEKFKEMAKNSISKEKIKNKQKEQS
                     L"
     gene            complement(92725..93747)
                     /locus_tag="PC366_000211"
     CDS             complement(92725..93747)
                     /locus_tag="PC366_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2575772.1"
                     /translation="MYLFDEQPIVANKTLAREIGLNEALILQQINYWIEINKKSGKNY
                     HDGKYWTYNSIRAWQENDFDYMSFDTVKRTFSKLEKAGYLLVGNYNKDPRDKTKWYTI
                     NNDKLEELYMDMDLKKQKIQTEALKNSMPNALGQNAPMDKGKISQCNNADCTNAQVQN
                     ALMQKDNLHQPLPENTTNNTTNNTTNNSAYISIHPSIKEKNQLFSENMKGGRIDISYK
                     NIYQNCLEELRHQTGYYEHMSIGNKSVAEEFDEILKILADVMVLDDESFITINQTKIS
                     VQVVKERFRKLNSGHLEYLVGVLRENEYRIRNIRAFVLTAAYNAPSGIDAYYSALVSY
                     DMRGGY"
     gene            complement(93833..94114)
                     /locus_tag="PC366_000212"
     CDS             complement(93833..94114)
                     /locus_tag="PC366_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575773.1"
                     /translation="MRWILKIILFPISIALSILIAFLSFLLGIGTAILYLLMMFCIFG
                     AIASFLQKEVTIGIEALILGFLLSPYGIPMVGTAVIAVLTGVKEAIRSI"
     gene            complement(94133..95767)
                     /gene="rlmD"
                     /locus_tag="PC366_000213"
     CDS             complement(94133..95767)
                     /gene="rlmD"
                     /locus_tag="PC366_000213"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDF2575774.1"
                     /translation="MLSKNEMYIVDIVDIGQGGVGVGKYNGITVFVEGGLIHDKVKVR
                     INKVKKNYAEGDIVEIIEKSPFRVKRVCSDNLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGIPIIGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGRENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYANLNDTDTVFDIYCGIGTISLFLAQKAKKVYGIE
                     IIDDAIKDAKINAKLNNIHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMNPERIVYVSCNPSTLARDLDYLNVHGFKCVEAQPVDMFPHSTHVETVALLS
                     KLDVDKHIDVEIKLDELDLTSAESKATYAQIKEYVLEKFGLKVSTLYIAQIKKKCGIE
                     LREHYNKSKKDNQAIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(95942..97702)
                     /gene="pyk"
                     /locus_tag="PC366_000214"
     CDS             complement(95942..97702)
                     /gene="pyk"
                     /locus_tag="PC366_000214"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HDF2575775.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEILTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRIIKNGNACVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSATDITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(97754..98713)
                     /gene="pfkA"
                     /locus_tag="PC366_000215"
     CDS             complement(97754..98713)
                     /gene="pfkA"
                     /locus_tag="PC366_000215"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDF2575776.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFAGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(98922..102491)
                     /locus_tag="PC366_000216"
     CDS             complement(98922..102491)
                     /locus_tag="PC366_000216"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HDF2575777.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     LDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSNEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKVAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFIE
                     LEDLYGAIEIIVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFADRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(102648..103595)
                     /gene="whiA"
                     /locus_tag="PC366_000217"
     CDS             complement(102648..103595)
                     /gene="whiA"
                     /locus_tag="PC366_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HDF2575778.1"
                     /translation="MSFSTETKNELARVISGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILEDKEGFFTINKISENLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKS"
     gene            complement(103612..104037)
                     /locus_tag="PC366_000218"
     CDS             complement(103612..104037)
                     /locus_tag="PC366_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2575779.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(104106..105212)
                     /locus_tag="PC366_000219"
     CDS             complement(104106..105212)
                     /locus_tag="PC366_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HDF2575780.1"
                     /translation="MAKLLIIVGILGWIALIVSLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDENLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(105224..106081)
                     /gene="rapZ"
                     /locus_tag="PC366_000220"
     CDS             complement(105224..106081)
                     /gene="rapZ"
                     /locus_tag="PC366_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HDF2575781.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIDEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(106112..106825)
                     /locus_tag="PC366_000221"
     CDS             complement(106112..106825)
                     /locus_tag="PC366_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HDF2575782.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYNDINILLGMECNILDDKGNIDMDDKFIRDFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVINAISNNDIFIITHPGDKGDV
                     YIEEVAKTAKKTNTRLEINSSHSFLNVNQLNKIKGLENKFIIGSDAHCPERVGDFKLA
                     MKTISDSNLDISLVENIII"
     gene            complement(106829..107743)
                     /gene="murB"
                     /locus_tag="PC366_000222"
     CDS             complement(106829..107743)
                     /gene="murB"
                     /locus_tag="PC366_000222"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HDF2575783.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKEESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDM
                     EGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(108016..108786)
                     /locus_tag="PC366_000223"
     CDS             complement(108016..108786)
                     /locus_tag="PC366_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDF2575784.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKIDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMATASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSIVVGGIYYLCYVKNS"
BASE COUNT        32985 a        21320 c        15036 g        39624 t
ORIGIN      
        1 ttatttaaca atttattatt gtaatatttt gaatatataa taaaattaat aataagaaaa
       61 ctttttataa atacactttt aattgtttaa attggaggaa aaaattatgg atgaaaatat
      121 aacaaaaaat aattataatg ttccatttga ctatgttcga aaaaaactca aagaattaga
      181 ccctcataca attagtaatt taagtaatat acctttcaat aatgatttaa atagattcac
      241 actcaatttt tttgatagac aatatattat agactatcca agtggagaag tttggaatag
      301 taatggtagc ctttgcaata actttgagct taaaatcttg atagttagat atttaatcaa
      361 tgctaaaggt atccctagaa ctaataaata tgtaactttt aaagaaatac caggaggcaa
      421 tgtttattat ccaaattttt taaacaggac tctatatagg ctttcagaag tttttacatc
      481 tcaaatagac aaatataagt tagttatgga gaaaattgga gctgaaaaag taaacatggg
      541 agatttagct tataggttta catatatggg taatacatct atgatattta tactttggtt
      601 tggagatgat gaatttcctc caaattcaaa tatattattt gattctaata tagtttatta
      661 cttcaatgca gaagatttag cagttgttcc tgatacagct ataaatgcaa ttttaaataa
      721 aataaatcaa ttataaatat aaataatatt ataataaagt ttttgataga tttaatagaa
      781 tataatatga aatggggtaa aaaatgaatg tagaaaatca atctttatca gatattgaaa
      841 taatattatc acacaggtat gataatggtg cagactattg gactacacct gataagcgtt
      901 taataaaagg ttctcctttc tctactcttg atagtgtact ttatctatta gagttaggtg
      961 tgaaccctga tgatacttta cttaaagaat gtgctgactt gatatttagc acatggcgag
     1021 aagatggacg tttcaaacta tatccaaatg gaggtattta cccttgtcat actgcaaatg
     1081 ctgctaacgt actctgtcat atgggatatg catctgacat tagaatgcaa aaaacgtttc
     1141 aacatttttt agatacacag tatactgatg gtgggtggcg ttgcaataaa tttagttttg
     1201 gtcgaggtcc agaaactgaa tactcaaatc cactaccaac tcttaatata ttaaatgcat
     1261 tccgttttag taattatcta aataaagaat caaaacttga caaagctgta gattttctac
     1321 ttgaccattg gactattaaa aaaccactcg gcccttgtca ctatggaatt ggcacattat
     1381 ttatgcaagt tgaatatcct ttccgtaatt ataacctatt cctttatgtc tacgttttat
     1441 cattttataa tcgtgcaaaa aaggataaga gatttttaga agcattgaag atacttgaat
     1501 ctaaaatgat aggtaataaa attgtcgttg aacgtgtagt tccaaaacta tctaaattat
     1561 ctttttgtaa aaaaggcgag tcaagtgaaa tagccacaac acactattac gaaatattaa
     1621 aaaacctaga aaaataatag ttatatagat aaaacatatt aaaaaatagt ggctttaaat
     1681 tttttaaagt cactattcta tataaatata acattataaa aaatatatta aactatttac
     1741 tcttttttaa aaccgttgat tttcttgcta tataaaaaac tattattata gaaataacta
     1801 ctagagaacc tctatttata aagaaataat tctttaattc attaaatcta acatctatat
     1861 tattaggcat ataaaacatc ttttgaatat aaaatccatt tacattaatc atactaacaa
     1921 atgggtacat atgtaaaata aaaaatatat cagcaaatgt atatgtaatt aatattgcta
     1981 ttgttgtaaa tctatttttt gttaatgtta atatcattag tggaaatgtt gtataccata
     2041 ataatgtagg aaatgtcttt aaaaacacat ctattggctt tacactataa acaaaatcta
     2101 ttttgtctat gttaaaacct ttcactgacg taaatgtata tactattgta attgaaatta
     2161 ataataatac agtatatata gctaatataa cacaccatct aaatactata aattgattat
     2221 attttttttt attatataaa gtaagtatct catttatatt acccaaataa tcttttgaaa
     2281 acacataaat tattgtgatt gctgacatta ttggtataaa aacatctgat atctttataa
     2341 ttcctaacca tcctgctata gaatatgtat ccattatagg tacatcatta taaaatatta
     2401 actcattata atctaatatg cctgtaataa atatgcataa tatagaaata attacaaata
     2461 ttaacacatg tttaagctct atttttttaa gctcaaattt tattaactcc aatatacaca
     2521 tttattttaa ctccttatgt aaaaagttta tataagcatc ttgtaaagtt gtatctatcc
     2581 ttaagctatc cttaagtttc tctgtatttt tacctatata ctttacttgc acaccatctt
     2641 taactcttct ataatcaata atatcaatat tacgttctaa atattcaaat tcatcattag
     2701 aaactactac tgaatacacc tcaaccatat caataaattt attaattgta ccatcatata
     2761 atattttgcc ttgatttaat ataattaatt tgtcacagtt aaattgtatg tcttctacta
     2821 tgtgagttga aattaatact atagaatttt tacttatttc tggtaacaat cttctaaatt
     2881 cattcctttg ctctggatca agaccaactg taggttcatc cataactatt aacttagaat
     2941 cacctattaa agcctgtgct atacctagtc gtctctttac accacctgag tatgtaccta
     3001 ttttattatt tataaacttg tccagattaa cttttgatac tactttttgt atatgtttct
     3061 ttaaatcatt cttagataca cctctcattt tagctacaaa ctctaagtat tcttgcccat
     3121 ttatattatt atacatatca aaatcttgag gtatatatcc tacatttgcc ttgattttct
     3181 cattgttttt gctatacttt atattattta attctatctc tccaattgaa gtttcataaa
     3241 gagtcactaa taacctcatt aatgttgatt ttccagcacc attaggacct aataatgcaa
     3301 ctactccatc tgttagggtt aaatttatat tatccagagc ttttttattt ttgtaattaa
     3361 aatttagatt tcttatttct aacttgttta tcatattaac ctcctttatt atttatctat
     3421 tataaggata tttcctgaaa gccaatgata aatagttatg ctaattttct ctccctttga
     3481 gtcttcatat aaaaattcat tgctaggtaa gtcagcaact aatatcatat taattttttt
     3541 tctttttatt gattccataa cattatctac ttcatctaca tattttttag catctacaga
     3601 tgctttgcta tcacctaata tttcatttct tgtttcaatt aaaaatttaa ttttttcctc
     3661 tatatccata tttacattac tatctgatgg atagattatt tttatatcat cttttacctc
     3721 ttctttaaac tcacctgcat atattgcaat atcatttgac tttccttcaa atatataatc
     3781 tttttttaaa aaattactag tcttattcag taaaggtaaa tttgaataga cattattttt
     3841 agaacttaaa tttattttat aagccataca acttgattga tttacttttg ggtaccacgc
     3901 taaagaacct ggtggaagca taatatcatc tttagtagct atatatttat tttgattcca
     3961 agatgtcaac acattaatat agccttcata ctctatatct aatgtcacct cgtcattagg
     4021 ctctaaactt tcctttaaat taacttcaat taaatccttt tttttgttaa attttatatt
     4081 ttccgaattt acttttatat attttatatc aaatatttca tctaaaatca tattaatatt
     4141 tgttaactct tcatttgatg tgtttaataa aacaattcta tcttttatat ttgacttgct
     4201 tttaaagtca atcttcatat catgcgattt tattttaata tcactaatat tagatttctt
     4261 taaatactct ccataactac gttcctcatc tctatatgtt gacatatcta ttgatatata
     4321 atttaatcca ataaataaaa tactgtacac tactataact attaatgatt taatctgttt
     4381 ctttctaata tcatttaata tcagatatgc tactattatt aaagtaattg caaatagtgt
     4441 aggtataatc ttatctataa catatgctga attattaact ttccctacaa aatcagaata
     4501 gtaagcatat gattgatctt caaatatatt aagtgattta aataatgctt taaaaaatgg
     4561 ttctttaata tcaataactc tatccaacat cttagttgat gttaaatata aaaatactga
     4621 tgataaggta atctttagta ttaaattatt tataataact gaaataaatg atatcactat
     4681 agataaaata gtaagtggta aaaaccattc aaataccaat ataaatatag ttgatttaat
     4741 cgttacaatt gataatgttc ttattaaact tgagtatgct atagcatata taattggtat
     4801 gcaacaaaat ataaagttgt ttctagttac agcaacagaa atacctaaaa aataatcaaa
     4861 attatttcta cataatattt ttacagtatc ataacttttt ctcatataaa aaattacatt
     4921 taacatggtt aaaatactaa ttgtcataca agtatataca ctcaaggata agtaatcatt
     4981 aaatgaaatt cctctattgg atatatgtgt ccatcgttgt atgagatggt aatttataat
     5041 aataactgtt attgcaaata aaatattttt tctaattatt ttggttataa agtctgatat
     5101 aaccttaata ctactcatat ttatgcccct cctagccaat cctttgatac aacttacaat
     5161 agattcaact atatttaata agttcaaata tttaccttga cattattttt taaaattaat
     5221 attaattagt gaaattaatt aatttagaaa atgttttata atcttactga tcattattaa
     5281 ccttcattcc aatatatatt aatatagcaa tccaatatat agaaattatt gcataaatca
     5341 catattgctg aaaaatatta agtattttac ataaaataat taaacatatt attacgaata
     5401 gtattttttg cacagtcttt ctataatgct ttttctcact ttcactaaga ggtttgtttc
     5461 tatgttctaa aggagctaac ttgtaaattg ttagtatact aataatcatt aataatacta
     5521 ataaatactt atatttattt atatctatat tattagctga aaaaatagtt atcaaataaa
     5581 taactgcaaa tgttaatgta cactctttat aattcctagc atgataacct cctgtgaact
     5641 gtcttaaagt gcaataacaa cttaaaaata taactgtatg tataaatcta tcaaaaataa
     5701 ttcctataaa taatgctacc gaaatattaa ctatgaaata aatcaaagtt tcaaatccat
     5761 atctatatat ttcaaaatct tcactttcta caatctcatt attaactaat atattggcaa
     5821 atttatatga taatctttta aacatatttc ctcctcaaca tgtaaaacct ctcctttaat
     5881 aagaagaggt ccttttatta atgttatttt tttagttttt gtaaagcttg tggctctttt
     5941 gcctgatgtg ctacccaaga acttgcactg tttgctgata atacagctat cccaaaactt
     6001 aatgctgaga tgtttttaag taagtttaac gctatttttt tcattttgta ctctcctaac
     6061 tttttattgg tatcattatt tttaatataa actcattatc tgagtaatta actattgttt
     6121 caccaccata tttatttact atatatttaa tactagcaag tcctattcca tgtatcttat
     6181 catcatcctt actagtttga atacgtttat caataagttt aatatcattt accttagtat
     6241 ttataaattt tattattgca aatttattta tatatgtagc tttaacttct attctttttt
     6301 ctagctcatt atttatatcc atacatgctt caattgcatt atctagtgaa tttgcaaata
     6361 ttgaacatat atcattattt tcaataaagt ttaatttaga tatatttatg ttatcttcaa
     6421 tttgaatatc atacttttta caaatactta ttttttctgc taaaattaaa tctaatgttt
     6481 tatttccagt atttttaaaa tgttcaaatt cacttatctg aaactctaag ttatctatat
     6541 atgatataat ttcttcttta gtgtcataat tttttataca aatcatatgg tttttcaaat
     6601 catgataaac atattttaat ctatcatgaa cttcgtttat attttcataa ttcctgtagt
     6661 ttgtttttat tctttcattt ataagttcat actctagatt taatttatcg tcttgtacaa
     6721 ttttccctat tactattaaa agtattatac ttgatgataa aatcaataaa attgcaaata
     6781 taaatataaa taagttttct gtagtaattg tattgactct taaattatat tcaaatataa
     6841 gtaataagct aactatatta gataatatag gtattcctat tagtatcata tctttaggtt
     6901 taaaatctaa agataattta aaatacttaa acaatataaa acctataaat aaaaatacct
     6961 ttgacataat aatagcttgt attctaaata agttttcatg ttgtgttatg ttaatattat
     7021 ttaatttatt tataaatact actagaccta ctgcagaacc ttcagcaatc attaatccta
     7081 gccaaaacaa taaactaact attatacttt tatatatttt atcttcatat gatgttatat
     7141 aaaatgatat tcctattacc atacatagaa gaatcttaat atttggaaac actttaacta
     7201 catttatgta tgccataaat ataaatataa ttattgttgt aaatatatat cttatattag
     7261 atattttcct ctttccaact aagtggatta ctaaaaaaaa tataatccaa tctatagtac
     7321 ctgaaactaa attaataata ttccaaaatc ctatacttag atttgttagc atactatatc
     7381 ccctaatata ttagttatag caagtttcaa gcctttaact ctatatttac ttattggaat
     7441 acttttgcca tctactataa cagtacttcc actcattgat tctactaatt ttaaattaac
     7501 tatatagcta ttatgacatc taaaaaatcc atattcattt aatatctttt ctattttaga
     7561 tatactcatt ttagtaatat acatatcatc atgtgtataa atcaatatat tcggtctatc
     7621 tgtttctata taagtaatag aatctatttt aattcggtct acataatttt ttacatttat
     7681 agttaagtaa ttatttctct ttttcatcat ctcatttata caaggtaata cacttttaga
     7741 aattttttct ttatttattg gctttagtat atatctgtat gcttttacct cataaccttc
     7801 ttgcataaac tctacaaatg aagtaacaaa tattatttct aacttatgat caaactctct
     7861 tatcttccta gcagtatcca taccatttat tgttttcatt tgtatgtcca taattaatat
     7921 gtctaaatct ttaggatagt tatttagtaa ctcttctcct gatgaaaatt catatatgtt
     7981 ataatttata ggatatgaac ttaatatttc acttaatata tcttttattt ttattcgata
     8041 atgtagttca tcatcacata ttcctatact aatcacaatt cttaaacatc ctttcttata
     8101 tatttttaat aaatatataa aatttctatt cattttacat attttaacat acttctgtag
     8161 caaatagcta tttagatttt aattttagct ttttggacat taagtattac tttttggatt
     8221 tacaatctat tttaattttc attataatac aattttttaa tatatattga atatatttag
     8281 cgattttaat aacatattct tcgagaagtt tttagtatct agtttttgtt aaacaaaaag
     8341 tatgcacctt cctttttata gtaatatttt aattatcgct ataattttga agaatacaca
     8401 ctatatttta aatattcata taaaacatat taaaaaatag tggctttaaa ttttttaaag
     8461 ccactatttt tttaaatgat gttcctgaaa atatattaag ttagttattc taatcaattt
     8521 gaagactttt gcttctcctt gcctatatct aacataattt cataatttaa tttacctttc
     8581 tttaaatcaa ctcctgagtt acttctaata atcccacaat ccaacatttc gtcaaatacc
     8641 ttcctagata aacctagttt ctcacgtaat aatgttgata cctttaactg acatggatat
     8701 ttactaataa tatgaacttg tgtaaggtca ttaatattaa tttcttgtcc tactatttta
     8761 tactctggaa taccaacttc tgctccattt ctatgtaaaa gttccgtatt catagcatat
     8821 tgcttagcaa gattataatc gtttgtatgg aattgttcta gtgtttctgg atttaagctt
     8881 tttggattga cacgagaata tatagttgag ttccatgttg aatcacaatt tgaacacttg
     8941 tatattaacc atatatccaa atatttatgt tgagcattaa ccctaaataa acctgaacaa
     9001 atatattcag tcttttttcc acatttctta caatacctaa ttacaggtaa ctgggagata
     9061 tattccacct cccaagtaat ttttttcata aatgcaactt cctttctata agattactaa
     9121 attaatagaa agttatgaaa aggtggaata taatcaagta tttttttcaa aacaagacct
     9181 cctaatttta ataaatttta atttcaaaca tataaaaagc tactacttct tattagatac
     9241 tttacaactc tattcgttat ctgctgtaca agttattgaa attatttaaa ttatagcatc
     9301 cacttataag aaactatacc tcaaacactt ttatcaaaag aaaatgagcc agtataatta
     9361 taaaactata ctggctcatt cttaactatc ttttcttttt tcttgtaata caattctttg
     9421 aatacttttc aaagacaagt aatatttttc tgataaatat ttcaaatcat atccaacttg
     9481 ataatcttca taaatttgca tatttctaat tgataaatct tcacgagtag acgtactact
     9541 tccccattct tttttattat tagactttct aggaatatag atatattctc catctacata
     9601 ttcctgtatc aattcaagta attcttctgg taatatatgt attgcttttt tatagctcat
     9661 tctgcactcc tattaaataa taatttttta ttaggaatag caaagggcta tttatatatt
     9721 aaattttata tttgcaatag cccttgctat gcaaaaataa agattaaatc aaacataaat
     9781 ctcacccctc cttatatatt gcaacgatac atataagtct atcagcagta taaatagttg
     9841 tcaattaaca taacttcttc atctaacctt tatattatct ttatttattt tcataattca
     9901 tctattttag agactaactt ttttcttctt attagatata tttaaagtta ttaatcaaca
     9961 taagtccttt atcttgaggg atttattacc gaacaaggaa ccccaactat acactttcca
    10021 caaatatcac aaccacctat ataagtgtat tttttttcat ttatcataca catttcataa
    10081 cacttattcc tattaaatcc atcttctttt aaagcttctt tcacgcattt gttgacacat
    10141 tttttgcaac tattattatg tttatacaag cagtattcat tttctggtct tttagttggc
    10201 tctaattcta aacttgtgat tatgcttcct attcttccac aacacccttt ttctgtaata
    10261 agcatattat ttaaaccaaa tgttccaaga cctgctatga atgctacatg tctttgtgac
    10321 cagtcactta ccaatttttc actgtcaaaa ttatacgacc caggaatagc atatgaatta
    10381 gcccccatct tctctagttc ttcacataag aaatcattta aatttgaaat caacatatta
    10441 gtttctatgt acgctcttgc ccatatttca gaacattcaa accctccaat attactatta
    10501 tttacacttt catcaaaagg tataaaatat gtaattatag tttttccatt ttccagaaaa
    10561 tcttttggca tagcatgaga tgttcctaca acacttttta gcttctgaaa catatcatct
    10621 tcagcagatg cataagcaaa caaaagttct tgccactttg tagttatatt atttgattta
    10681 tgataatttt ttacaaagtt gttcattgat gtttcaatct tatttttcat agtatcaccc
    10741 ctagataatt ctatatttcc aatttaatgt tattatttta tattatataa tagtatttta
    10801 taatatgcgc actaattaat attaaaacta tgttcatcaa tcattcttaa aaaagctcct
    10861 aatatcaata cgatattaga agccttttct tatctaatct aatttattgc aattcctgca
    10921 cttgcatatc ctgctacagt attaactaat gaaagacctg aagctgttgc agtaaatact
    10981 agtaagaatc gagtttctgc tgttgctgct atatttaatc ctgttacaat tccactagaa
    11041 attgaaccaa ctgataatat acctgtaagt ggtggagcta gtgtaactgt cgctcctggt
    11101 acagctgtaa atgagttatt tggtgcagta gattggtaaa gtgttgctgt aattgtaatt
    11161 gttgaaccaa caagtgaaag tgctgctgtt gtactgaagt atgctgaaat agatgttatt
    11221 gttccatctc ttggcattga aaatgcaaag ttagtcaatg tccctgctgc gtttgtaagg
    11281 tctattactc caccaactat acttaatcct ggagctgaac taccaaagcc aacaaaacct
    11341 ggtgtaccta ctaatcctcc agctatagtt gtaagtgata gtggtatacc tgatgcaaaa
    11401 ggtattattg cactagcacc tgttgggcct gttggacctg ttgcccctgt tgctcccgtt
    11461 gctccggttg gacctactaa tccatctgcc cctgttggac ctgttgctcc ggttgcccct
    11521 gttgctccat ctgctcctgt tggacctgtt gctcctattg ggcctgttgc tccggttgct
    11581 cctgctaatc ctgttgctcc ggttgctcct gttggaccta ctaatccgtc tgctcctgtt
    11641 ggacctgttg cccctgttgg acctgttgct ccatctgctc ctgtatttcc tgttgcccct
    11701 gttgctccgg ttggacctgc tactccatct gctcctgttg ctcccgtcgc tccggttgga
    11761 cctactaatc catctgctcc tgttggacct gtcgctcctg ttgctccggt tgctccagtt
    11821 attcctactc cggttgcccc tgttggacct gttgggccta ctaatccatc tgctcctgtt
    11881 gcccctgttg ctcctgttgg acctactaat ccatctgctc ctgttggacc tgttgctccg
    11941 gttgcccctg tcgctcctgt tgctccatct gctccggtta ctcctgttgc cccggttggt
    12001 cctattagtc ctgctgctcc tgttgcccct gttactcctg ttgggcctgt tgctccggtt
    12061 gctccggttg ctccggttgg acctattaac cctgttgctc ctgttattcc tattcctgtt
    12121 gctcctgttg cccctgttgg gcctgttatt cctattcctg ttgctcctgt tgctcctgtt
    12181 gggcctgtta ctccatctgc tcctgttgcc cctgttgggc ctgttgggcc tgttactcct
    12241 gttgctccat ctgcccctgt tgctcctgtt gctcctgttg gacctgttat tcctattcct
    12301 gttgctccta ttgcccctgt tggacctgtt gctccaggtg ttcctgtcgc tcctgttgga
    12361 cctattaatc ctgttgctcc tgttactcct actcctgttg ctcctgttgg gcctgttgga
    12421 cctgttactc caaatcctgt tgcccctgtt gctcctgttg gacctgttat tccatctgct
    12481 cctgttgctc ccgttggacc tgttggacct gttactccat ctgctcctgt tgctcctgtc
    12541 gctcctgttg ggcctgttgg gcctgttact ccaaacccta tagctcctgt cgctcctgtt
    12601 gggcctgttc cccctgttgc tcctgttgga cctcttaatc ctgttgctcc tgtattccct
    12661 gtatttcctg ttgggccagt cggaccggtt ggtcctgttg ggcctgttcc ccctactcct
    12721 ggacctgttg gacccgttgg tcctgttggg ccggttctac ctcttggacc cattgggcct
    12781 gttggaccta cacatgatgg tggacagcaa tgatggcaat cacagctatt ataatcatca
    12841 cgaccattat tacaatcatc atatttatca tagccattgt tgtaatcatt atcatcaaat
    12901 ggtccaaaat atttatttct actcattatt aaaagcacct cctgatatat ttgagctttt
    12961 aagctctata tataatatgt caaatttagt atgattgtga cctatcaact atttttaaat
    13021 ttactaaaat aattttcatt gtgcaaaaca gcactatcgt taggtttgat ttcttttgtt
    13081 ttttcatgat aataaatagc tttatctgat tctcctaacc tgtcataaca gacacttaat
    13141 tgtatagatg gtatatatcc ataacaatca tttgacttaa aacctccatt agtatcattc
    13201 ttatctcttg ttaatgctac cttataccaa aaaatggctt ctttatattt ttgtctatca
    13261 aacatatgct ttcctatgtc acaacaaatt tctgctcttg gctcatcaaa ttcgaaactt
    13321 ctaaacaatg aatataaggc acttttttca tcattaatta agtaataaca tgtggctaaa
    13381 tctctgcagg cactgataca atcctcaatc catcctcttg atgagtctaa aaacttagta
    13441 aaaccttcta ttgcttcttt atacctagca ttatagtaca actctctaga gtaatagaat
    13501 tggtgtcttg gctccaatgt ttttccttct gaaatcattt tttcaaaaat tctaagattt
    13561 cttagagggt cctgtctatg aagcttttta tgagatattg caatgtcaga ataaaatacc
    13621 tctccaaaaa gaggtactac ttcatgaata gggtcaaccc atttatgatt agaacttctt
    13681 ttaaacaatc gttctctata atatgagaga gttgggttac cattttcatc aaaggataca
    13741 ttgtattttg ccataacaat atcaatggaa gtatccaagc tttctttaat ctttaataat
    13801 ttttctctat cagcttctaa aattatgtca tctgcatcaa gccacatagt atagtcttta
    13861 gaagctttag aaaatgaaaa atttcttgca gcagagaaat catctatcca ttcgaaatcg
    13921 tacaccatgt ctgtatattt tgagactatt tcttttgtgg aatctgtaga accggtatct
    13981 acaattataa tttcgtctac tatatccttt acacattcta agcatctgcc tataacttct
    14041 tcctcattct taacaatcat gcacaaactt attgcaatca taatgtacaa ctcctttgtc
    14101 ttctatatat tgcagacata agtaatatat ggtattttct cttgttttgt tattaaattt
    14161 ataaaaactt ttgacgacag aaagttacta aagaacctta tcttttatgt attttttata
    14221 gtagaattta ttaaacttga aatttggtaa taattgttga aatgataaaa ccatatttaa
    14281 tttcatacaa aaaagagtgt cccataaact aaaaagttca ttttgagaca ctcttattta
    14341 atattatata tatatttgta aaacagacat tttaatatga tactttgata ctttattcat
    14401 tcctattcat tcctattcat tatataatca atcagcccgt actctttagc ctctagtgca
    14461 gtcataaaat tatctctatc tgtatctctt ctaatatctt ctattgattt acctgtattt
    14521 tcagaaagaa ttttatctaa tcgttctttt attttcaata tattatctac agctattttt
    14581 acatctgttg cttgaccttt agctcctccc attggctgat gaatcataat ctctgaattg
    14641 ggtaaagcac atctttttcc atgtgttcct cctgcaagta aaaaagcact catacttgca
    14701 gccataccaa tacagatagt cgatacatca catctgacat aattcatagt atcatatata
    14761 gcaaatcctg atgtagcaga gccaccaggg ctatttatat atataattat atctgaatct
    14821 gggtcttctg attctaaaaa cagtaattga gctactacta aacttgcaat agcatcatta
    14881 atttcttctc ctataaatat aattctatct tttaataatt ttgaatatat atcataagac
    14941 ctttcccctt gacctgtttg ttcaattaca tgtggcacta aactcatgct actttcacct
    15001 cacaattaat attaaagtta agataagaat tgatttcatc tcttctttgt ttataattca
    15061 tatttgcata agaaatacat ttttcgcttt gaatttgatg atttagattt aaaacaaatc
    15121 tctgttgaat aggataaaat tcatctttat ttctatatac ttgtggagat tctttatata
    15181 aatttctaaa tgctagtgta aaagattgat gtgtagaata tcctactgta atagctatat
    15241 ctataatata tttgtctgta aatataagtt gtctagctgc ttcagtaagt ctcctcctct
    15301 gtatgtattg atggatagta catcctacaa catttgtaaa cattctgtgt aaatggtatt
    15361 ttgaataatt agcaatataa gctattttat ctaaatttag attttctgta agattttctt
    15421 ctatataatc aattatctcc ataataacat ctgtatttgt tttcaactct atcctctcct
    15481 tttaagtatt ataacctatg caaaaagttt tttcttaata taaattgcta tcttaattta
    15541 gtgtatagca ataaagtatc gataaaacaa tatcaagtat ttttatacaa aaatattaat
    15601 atatatttct tttaaagttt aaacttaatt acatctatta tatgtagatt gctacatgtt
    15661 ttatctatgt accttgattc atatgtatta ttttgctgag tatttttaca cctttttcaa
    15721 tttcatcaaa actaagatga gcataaccta gtataatttc atggtcatat tctaatatat
    15781 tctcaattgc atattgttgt ataggataaa cttttatacc tgcttcaaaa attttatgaa
    15841 ttaaactttc cgtaaattta acattataga aatgagcaac tatatgaagc cctgctgctt
    15901 caccttttat tttaaattca tttttaaatt ccgtgtttaa aacttttatg agatatttac
    15961 gttttctatt gtacaacttc ttcattctaa atatgtactt ctctaaacct ccatttccaa
    16021 taaattcagc taatacatat tgcaatattg tttctgtatg aacatcagag tacattttta
    16081 aggttttata gctttctaaa atattgtctg gtaataacat aaatccaaca cgaatagctg
    16141 gagataatat tttactaaaa gaacctatgt aaattacttt atttgggcta agttcataaa
    16201 gagaactaat tggttgaccc tcatatctaa attcactatc ataatcatct tcaattatat
    16261 agtaatcatt ctctgttgca catttaataa gctctagtct tctttgaata ggtaaaatcc
    16321 ctcctaatgg atattgatga gaaggtgtag tataaacaaa agaaatcccc tttattgatt
    16381 ttattaagtt ggtattcatt cccttatcat ctactttaat tccaacaact gaatatccaa
    16441 tagatgaaat aacctttaat aagcctttat gaatagggtc ttctacagca acctttttat
    16501 tacttttgta taaaagctgt gaaattaaag ataaaccttg tgttgaacca gaaacaatca
    16561 taatgttttt ggaattacat ctaattcctc tagtacgaaa taaatactta gatatttcca
    16621 ctcttaaaac ccatacacca gctgtacttc catatctgaa atccgaatct gataaatcat
    16681 acagtatttg tttatatagc tttgaaagtt ctttgcgtgg aaatagtttt aattctggaa
    16741 ctcctgaacg aaaatctata taattttttt gtttattagt atgtaaatct ttttcatctc
    16801 taaaagtatc atttaactta aaatcaactt tatgccctga tattccttta gctacaattg
    16861 ttccatatcc attccttgtt tccaaatatc cttctgcaat taattgatta tatgcatcta
    16921 aaactgtatt acgagataca gatagttctt ttgataaagt cctagatgat ggcagttttt
    16981 gctcaaactt taagcttcca tccagaatca tatcttttat ctcacaataa atttgtcttg
    17041 ataatgatat attactattt ctattaatcg taatccacat tctaatacct ccaaaagtgg
    17101 ttctataaaa ttactataaa aatggaacta caaaatccac ttttaacttg ctaagattat
    17161 atcataaaat ataaaataaa aaggagtcta tattatgtta gaaatatcac ataaagttaa
    17221 agaaatttat cccaatatta aatttggagt tatggttata aatattacac attcaaaacc
    17281 taataaagaa aattttttag ttcttaaaaa ctctacaatt aaaaatatta tagaacaaca
    17341 cccagaatac aatcgtaaag aaaaaattaa aacagagcct gtttcaagtt atataaagta
    17401 ttataaaaaa ttcaagaaaa cttaccctgt attgcttcaa ttagaatcta ttctattaaa
    17461 atcaaaaggt atcccagatg taggtgtaac aattgagtca atgtttttag cagaattgaa
    17521 aaatcttctt ctaacagcag gtcatgacct tgataaaatg gaattacctt tgaaaataga
    17581 attagcaaat ggaagtgaac atttttatgg tataggtggt aaagagcata ttttaacaaa
    17641 agatgattta tttttatcag ataatattgg tatattatct agtattctta atggccctga
    17701 taatcgaaca gctataacaa aagatactaa aaatattatg tattttgtat atggacctga
    17761 taaaatatca gaaaagcaaa ttcaagacca tttaaatgac ataaaacact atatttcaag
    17821 tgcttttcca gatttaaaag ttaattcaat tgatatattt tagttaatat attaaaatcc
    17881 tcataaatat tttgaataaa taaattagtg aagtatacat tctagttaaa ctagatatac
    17941 ttcactaaaa ttaattatat gtagatatta tttattttga attttgttta taataaacac
    18001 tttattacat ttatcctatg aataacttaa ttttataatt aaagagtttc ataagaaaca
    18061 atttcactta aaggaacacg agttttttca tgtctctctg ggctctctgg tatcttagat
    18121 tcatatccca tcaataatat atttattggt tctagattat ctggcaaact aaactcttct
    18181 ctaattatat ctggattaaa atagcacacc caaacacttg ccaatccaag ttcagttgcc
    18241 tgtaacatca tatggtctgt aactatactt gtgtcaatat ctgtaagttg tctcccatca
    18301 aaaggtcttg tccaaacttt gtctttatct ccacatacaa gaattgctaa tggagcatca
    18361 tatatattgg cagccttaga aagtttattt ataccttctt tttcctgaat aacaatcaat
    18421 ctttgaggtt gacgattacc accagttgga gctattcttg caacatctaa aaccttctca
    18481 agtttttctt tttcaacctt tctatcttga taattacggc aagaatatct tttttttgta
    18541 agttcaacga aattcattta tttaccccct attgttttat taggctaagt tgatgattta
    18601 tttaacctat gctataattt tatcactatg gtactatatt acaataatgc acttttttgt
    18661 aatatagtat ctaaaaagat actttaaaat aaataaagga gctcaaaaat gaaaaaatgt
    18721 ttagataatt acagttgccc aatagaagca acacttgcat tgattggtgg taaatataag
    18781 acacttatac tttggcatct taaagacact atattgaggt ttaatgaatt aaaaaaatta
    18841 attcctaaag caacgcctaa gatgttaact caacaattac gtgaattaga atcagatggt
    18901 ttaattataa gagtggttta tcctgttgtt cctccaaaag tagaatactc gctatctgat
    18961 tttggaaaga gtattattcc aattttagat tccatgtgtg actggggttc tgattactta
    19021 gaaagtctat agagcattac agtttaaatc ccattgctaa tttaacttca tccatttgtt
    19081 ctctagatgt caacatttct aaaagcttaa aagctacatg tggagctgtt tctggacaat
    19141 atgaggttat aatattttta tctacaacaa ttggttcatt aactacattt acatcaaact
    19201 cacttaactg tctttgtctt ttaccatttt tcaaatgata tgtagtagct ttacgatttt
    19261 ttaaaacacc actttttcca actggcaatg ctgccacaca aatagaagcg attatttttt
    19321 cttttgaatt aaactccctt attagattta aaaaagatga atcatatgct tcatcataaa
    19381 atccaaattc ttcaaatcct ccaggaatag ctagggcatc ataatcatca acacatactt
    19441 cttctatcgt cttatcaact aatacttgta tattaaatgt actcataact tgttttttaa
    19501 atccacaagt cactacatca atatcatgcc cataatcgtt acgagcccat cccataacat
    19561 ctacaaatac actaaattcc atagtttcaa aaccttttgc taaaaaaact aaaactttca
    19621 tattctattt tcctcctaaa atataattaa cactttacta gtaaattatt taaaaaatat
    19681 cttttattgt attaaattct tctttaattg tagataaaac aatggttgta ttagcttttt
    19741 gaatcccccc aatttccttc aaagtcactg atataaactc ttcaagatta cttgtatctt
    19801 ctgctaatac ttttattaag taatcatact ctcctgaaat atgatgacat tctaatacag
    19861 tatcatattc caatatagtt ttcttaaatt ctttcatact tttagataaa tcagtattga
    19921 taaatataaa agccaaaagc ttatattttg ttttttcccg attaatttga atagtgtact
    19981 tttgaattaa atttgactgc tcaattttcc ttatacgctc tgagactgct ggtactgata
    20041 aattaatttg tctgcttatt tcagaggttg aagccctact attctttttt agagaattaa
    20101 ttatttttaa atctatttca tccagagcta ctcacctcct taattattta atacaatttt
    20161 agctaataat ttacattaag taaataaatt taatcatttc aataaaattt aatacaaata
    20221 tgttattttt ccttaaaatt ttagttttct ttaatcaaaa cacatataat acttaaaatt
    20281 atttaagttg aattaatgtt tttattttgt ataatatatt agaaccttaa tatatcattg
    20341 aaaattcaac aatactagac atatacttct acatgttgta atatttatga aaatagtatc
    20401 cctatatcaa aagtataaaa ctcataatct taattttccc atagactata aaattttatt
    20461 ggtagcgagt cttcaaataa ctttgtaatg atagatttac taaattaata taatatatag
    20521 caaatataac tttcttattg actataacca agtattatga taacataact taagctataa
    20581 ttaataaaac atattttaaa taaataagat aatccacaaa gtacaaaagt acaatttaaa
    20641 tatagataaa ctagaattaa tactaaaatt aggatgtgaa taattatgat ttatatagaa
    20701 ttagttaaac ttgttagaaa acttaactct acacaaatgt atacgatgaa gcgttgtgta
    20761 gaggttaatc tgaaagctta aagctttcta tcttcatcgg caaatatagg tttagtatag
    20821 ttttttggct atgcttattt aaaattacct atttgccgat agatagtata gattttctgg
    20881 tcatagacaa caatgcttgt ctatgacctt ttgtttttcc aaaagcagag gtcggcattt
    20941 tacaatgcca ttcctctgct ttttttattt ccataaattt tttaataaaa gaaaaggagt
    21001 ttgaattatg agtttattaa aagtaactaa tttatcacaa tgttttatgg ataaatcact
    21061 gtatgagaaa gctaactttg atttattcaa aggtgaacat ataggtgtag ttggccaaaa
    21121 tggtacaggt aaaagtacat taattaaaat tttattggga gaagttgttc cagattcagg
    21181 agaaatcaag tggcaaccta atatcaatat aggccattta gaccaatatg cagaaatcaa
    21241 tagagataca acaatatcac tctatttaca cactgcattt gaagaacttt ataaaataga
    21301 aaaggaaatg aatttactct atcaaaaaag tgctatatct gaaaatgagc aatatctaat
    21361 caaagcatca gattatcagg aacaactaat agcaagtaat ttctattcta tagataatga
    21421 aataaataaa atagcaaatg gtcttggatt agattcaata ggaatgaatc gtgttgttga
    21481 agagcttagt ggtgggcaaa gggcaaaggt aattttagca aaattgctac tttctaacca
    21541 tgatgttcta ttattagatg aaccaacaaa ctttttagat aaagaacatg ttgaatggct
    21601 ctcaaattat ttaaatacat ttaatggggc atttattgta gtttcccacg attttgattt
    21661 tttagaaaaa atttctacag gtattcttga tatagaattt ggtatgatta aaaaatatca
    21721 tggaaaatat tcagagttcc ttaaacaaaa atcacattta agagaagatt atattagaag
    21781 gtatcaagca caacaaaaga aaatagaaaa agaagagaca tttatacgta aaaataaagc
    21841 tggagtaaat tcaaaaattg caagaggaag acaaaaacaa ttggataaaa tagaaagaat
    21901 agctcctcct agttttacag gaaaaccaaa tattcaattt tcagaaattg aaatatcggc
    21961 tcaaaatgct cttactataa caaatcttga agttggatac tactattctt tacttccaaa
    22021 attaaatttt tctgttgatg gaggtcaaaa aatagttata actggtttta atggaatcgg
    22081 taaatctacc ttgttaaaga cattagtcaa agatattcct cgtatatctg gagatttcca
    22141 gttttcagaa caagttaaaa ttggttatta tgagcaagat ttaaaatggg aaaatcctga
    22201 taaaacccca cttcaaatag tagcagataa atatccaaaa ttaaatacaa aagagattag
    22261 acgtcatcta gccagatgtg gtgtgaagga agagcatgtt tcaaggagtg tatctacttt
    22321 aagtggtggt gaacaatcta aggttaaatt atgttgtatg atgttatctc cttgtaattt
    22381 tcttattctg gatgaaccaa ccaatcactt tgatgcagag acaaaggatg ctttacaaaa
    22441 tgctttgaaa cagtttagag gaagtataat cctagtttcc catgaagaaa aattttataa
    22501 aggttggatt gataaagtgt ttaatataga aaaacaatta gtataagttt atacacaata
    22561 tacaatatta tttaattgat atttcaatgc aaattttaat gttctagtta atgtttcact
    22621 gcaaataaac taaaaaaatt ttattagaac ataaagtaca ttaccaggat ataaacttaa
    22681 tgaggctatc tcaaaataga gatagacctc ttcttcattg ttgagataac gaaaatacat
    22741 ttgacttcac acataaaaga atgcctcatt aactaaaaat tcaacttgag acatcttcat
    22801 taatattaaa atctattcta atcgattcta ttcacaagtt tatatcctag tcctttaacc
    22861 gttataagta ttttaggatt tgaggggtta tcttcaattt tttctcttat atgtcgtata
    22921 tgcaccataa ttgtattgtc acaaatacta ctatatactc cccatacttg ttcatagagt
    22981 ctttcttttc ctataatttt atttacattt tgagccatgt agcttaaaag atgatactcc
    23041 cttccagtta actcaatctc atttctatct ttatatacac ggtttccttc tatatcaata
    23101 gtaatatctc ctattttaat aactgcacta tctgatggta caatgctttg atactgttgt
    23161 ctacgtaatt gcgctttaac tcgaaaagca atttctcttg gactgaatgg ctttgttata
    23221 tagtcatctc ccccactact aagacctagt attttgtcaa tatcatcatt ttttgatgat
    23281 aaaaaaagaa tagaacagta tgaaaactct cgaatttttt tacacacttc tataccatct
    23341 atatctggta acattatatc aagaatgaca acatctggac atgctatctt acacagcgaa
    23401 atagcatcta aaccattata agctttaata atgtttttaa aaccatcatt tatgagtact
    23461 tcttcaatta aatctactat atctttttca tcatcaacaa gtaatatttt tttattaaaa
    23521 tatgtatcca tattgaaatc tctccataaa aatttattat attctaatct tgcagtatca
    23581 atatcttgtt tttttatatt cactactctt gcttttacat tactaatagt aacatctcta
    23641 atagacaaat tcaatcacta tgaaaattaa gataagtttc tttaaaataa agtgtatgat
    23701 acattaaaac ctatagaaaa ttaatttcat ccaaagttta taatattaga ctaatacact
    23761 tacagataca gatacagatt aatacaatag taaaataaaa ggagttgtct taaaattgac
    23821 tttttctaat caaactttaa gttcaactcc cttttaaact tttatatgtt atttttatta
    23881 attctttata tcaattataa ctttaatttt caatagtata tatctaccac taattgaatt
    23941 acttattaaa acataaaata tctacctaaa ctatttattt aatatctaca tatatttata
    24001 tctattctta tacttacata tacaaaaaat ggttaaaaat aaagttaaaa tctcagcact
    24061 tggtactgct aaccatatcc catttatatt taatatattt ggcagtatca ataaacctat
    24121 agttataaat ccaaatgtac gtagaaaaga taatattgca gagaccttgc catttgacaa
    24181 tgctgtaaac atagacgaag taaaaatatt atacccacaa aaaataaaac taaaagaaaa
    24241 tatataaaat ccagaccttg caatttcata aactcggctt cctctttgag aaaaaatctc
    24301 tacaatgatt ggtgaacatg atatagaaaa gataaatacc aataaagatg ccactgaaat
    24361 aaataatata caaatcttaa aaacatgatt taactgtgta ttattttcac ttccatagtt
    24421 ataacttatt attggtgcaa cacccattga gaaacctata taaagcgaag ttaaaagaaa
    24481 ttgagaataa ataattattg taatagctgc aactccatcc tcaccaatta atttcatcat
    24541 catagcatta aataaaaaag tagtaactgc tgttgatagt tgacctacca tttcagatga
    24601 accattaaaa caagcttcaa ataatattct tttatctagt ctgggtatac aaaacttaag
    24661 taactcttta ttttttgaaa agaaaaccat acctgaaacg gtaggaatta ggtatcctac
    24721 tccagttgca agtgctgctc cactaatacc catttgtaac agaacaatga acacatagtc
    24781 aagaattata ttagcacacc cagcacctaa cactagccat aatccaaatt gaggctttcc
    24841 agctgttaca aataaacatt gaaataatac ttgtagtata tttgcagaag caaaaaccaa
    24901 gataataaaa agatatgaac gacaatattt aattaaaact tcacttgctc ctaaccatat
    24961 aatgatataa tccataaata caatacctat accagtaatt attaccccaa ttacaactcc
    25021 tgataatacg attaaagaaa aagctttatt tgctccctca atatcaccat ttcccatctt
    25081 acgtgctaca atagcacttc ctccagtggc aagcatagtt ccaattccaa ctataagatt
    25141 aataattgga catacaatat taattgctga tagagcattt gtattaataa atcttgatac
    25201 aaatatagta tctacgattg tatacaaccc cataaaaatc atcataaaaa tagtaggaaa
    25261 tgcaaacttc aatagagtaa ataaattaaa tctttgtgcc agtaaattat cttgctcata
    25321 aagattatct tgttcatgat tttctgaata atatacatca ctcattttgt ttatttttct
    25381 gtacattaat tatttttaaa atatattcca aacaattaga catttacaga cctcctttct
    25441 gcataagaat tatatctaat tatttggata tagttttaat taatcttgct tttttacaca
    25501 attatatttc tactaaagaa acttttaaat ccttacttta atcattttat agctttcagt
    25561 gcctttagcg caaatacttg ttcacatagt ttagtgtcat atgaaacgta tttatatata
    25621 gttatacatt gtctattttt actaatttat taactacttg cacttttata atgtctcata
    25681 cctaacttcc aaaatctcca cataaacaat gtaaacaaaa atacaattaa aattgagtat
    25741 attaatccat taattgttat tgtcccagcc aaaatttgag tcggaattgt cgacataatt
    25801 ccatatggta agattaaata gaataatact ttaaaaacac cttcatatat tacaccagga
    25861 attttcatat tcattggcaa taaattatct tctaatctca ttatcgcaga agatgatata
    25921 acaaaaaatg aaactgttct aagtatgata catacatcat aaaaaagtaa tgtcatcaat
    25981 aacaccatga aaatatatat tattatcata actaaagtta tctctgagtt taacttagat
    26041 attccatata aaacaataag tatacttgct agaattaatg gtgatgaacc aatattaata
    26101 ttttcaaatg ttaacctaaa tagtgggtct aatggttttg taatatagta gtctaattct
    26161 ccttcttgga tttttcgtgg aatatcataa ataccaaaaa agaaaatcgt catatttatc
    26221 gcatttatta atgagaaagt tcctataaat attaacatct ctccttgttg ccatccccct
    26281 attgagtcta catgagaata tatactatta aacattagaa gttgtaatat aaataatgaa
    26341 ctatctacaa aaaatgctcc aaaaaaatca aatctaaata ccatcatctt tgataatttc
    26401 atttttaata acataaatat tattttcaaa ttttttttca tcatataccc accccatcaa
    26461 ataatgttct cattctttta tacataactt tatttactac agaaaaaaat aaaacccata
    26521 atgctagaat aattaatcct tgtattgcct cattgctgtt tctacctatt agtaacatag
    26581 atggcaaata tgttgtataa taaaatggaa ataccttcat aactgttact atagtttctg
    26641 gtaagagtac aagtggtatc attgttcctg taataaattc aacaatattt tcaattatca
    26701 ttctaaaaaa actaatctca agaaatttaa atgacaaaat cccaataaag aagtggagtt
    26761 tcatcataaa aataaaccct agaaaaatca tcaaaattga aattaatatt tgaactggat
    26821 ttgatgtaaa ggcaaaatct attttaaata taaaaatcca tacaaatgca gaaatcatat
    26881 taaatacaaa ataaaaacat gtcattccaa aatttttagc aataaaataa ttttgaacat
    26941 taattggaat aatcatgtac tttgaaaatg tgcccaattt tacacgatta catatctctt
    27001 cactggtact ctttgacata tcaatacctg ctaaaaatga gcttattata tagtaagaca
    27061 acatagagtt aaatgtaaaa ccagagacta ttttattttc accaaaaatt gctttccata
    27121 aaatataagc aaataaaatt tttacaatcg taaacaccat attaaccacc acatcaaatc
    27181 tccagataag ttgcacttta aagttaattt tggctacttc ataatacctt ctaatacttt
    27241 gtttaaattt ataaaacatt gaataatttg aacttgcttc attatagttg ctcataatac
    27301 tcatcacttc ctttcttata tattctctct acaatactac ctatatcttc ttcttcaatc
    27361 attacatctt taacatcata tttatcaaaa atccatttaa tcgtttcatt tcctctttct
    27421 tttagcacaa ttactgatgt cttatgattt gtttgttcaa caactttaca atcttttgga
    27481 aatacaatgt tagtttcatt ggaaaaacta actgttattt ttttatattt ttgaaaatga
    27541 ttaaatagtt tctctgtaga accatcatat attttacggc tattttctac aacaatactt
    27601 ctactacaga gactcttaat atcttccatg taatgagaag taagtataat agtagttcct
    27661 tttgtttcat ttacttcttt taggaaatac ctaatttgtt tttgggctat agcatctaag
    27721 cctatagttg gttcatccaa aaataatatt tttggattat gtagaagggc tactattaat
    27781 tccattttca ttctttctcc taaagaaagc gtcctaactt gaacatttaa atagtcagat
    27841 acctcaaata attcgataaa gtaatccaag ttttttttat attcttcatt agatatatca
    27901 tataattctt taaataaaag aaacgtatct gctggtgtca attcaaagaa tagttgactt
    27961 ttttggccca taacaacagc atattgtttt ttaaaattat tttctaattt gttagggtaa
    28021 taacccataa cagatatttc tccagaagac ggtgcaataa taccagttaa catcttaata
    28081 agagtagttt tgccagctcc attttgacct attaatccaa caaattctcc ttcttctatc
    28141 tttaaatcaa atgacgatat agctgttttt tctgtatatt tcctattaaa taaagacttt
    28201 acactcccca taaatcctgc ctttttctca aatcttctat aagatttagt cagttcatta
    28261 agttcaatta tactcatttt aactacctcc atatttcata atttatataa aaaaagtcca
    28321 caggtatata tctgcctttt tctgtgctta tatttaacag cacaaaaaca gaaaactcct
    28381 gtggactaga aaaattaatg ctctctattt caaaatagtt atcaaaataa tactatacaa
    28441 aattaataaa agtgtagcag attaaagcct actacaccat aatttaacaa agtaatatat
    28501 attttaaata ctatttgttg tcatatgtca gttatctata aaggcagaat aagacacaaa
    28561 aattaaatgt attaaaaata cacttaaaat ttctgattat acagaatata tgtgtctcca
    28621 actatttaat tgttggttac cattatataa ctccgacatc aaggcactcc tctcataata
    28681 ttattattga tatcatatca taaaggttat ttatgttcaa gtatggattt atatactaat
    28741 acatttagct tatttcttca gggttgaatt taaatttcat ttataatatt cgtttataaa
    28801 ttaaaaatat aatacgtata ttaaaactgg ttattttact gtaatatttt tattgtaaaa
    28861 gatatacttt tacctataca ggatgtaatt tctttagttc tatattataa taatattgta
    28921 ataagagttc aacttataat acagtaaaat ataaactgta aatcttaagg gggtaatcta
    28981 tggaaaataa tacaatacaa aaacaattaa gagatttatc aaaaaaaatt tggcatattt
    29041 atattttaaa tccagaagaa gaaaacctta aatttattat ttccttatta gataacaacc
    29101 ttgcattaat tggaacagga aaacatgaat tttacgaaac attagaagaa tttattatag
    29161 gtcttgaaaa agaccaaaca gaatcagagc aaatagactt tgagattata gatgagtggt
    29221 attcatgtac caaagttaca gacgaagctt ttatagtata tggtactctt tgggtaatag
    29281 aaaaagatta cctagaaaaa gatatctatg tagaaatgga tactcgattt actatggtat
    29341 acagagttac agatgatatg attaaactta tccatgttca ccattctatt ccaaactttg
    29401 accaaatgaa agatgagtat taccctaaaa caataactga aaaagcacaa gaagcactag
    29461 caatggcaaa tgaatttaaa ctaaaatcag aaaaagacct tatgactgga ctatacaata
    29521 gacatttttt tgaagtacac ataaaagaaa tgcttaaaac tgtttcatat ggatactttt
    29581 acatctttga tttagataat tttaaacagg taaatgatat ctttggtcat gttcgaggag
    29641 atgaaatact aatacagttt tcaaatattt tgactaaagt attcgtaaat gatgctatta
    29701 ttggaagact tggtggagat gaatttgctg tttttgaata tagtaatcaa tcaaaagaga
    29761 atgttgaaaa taaagcaaag aaagttttag aattatgtct agagagtaat tcttgttcta
    29821 taggtatatc taaattagaa aataaatctg atactttcca gtctttatac aaacaatcgg
    29881 attatgcttt gtattattca aaacgaaata ataaaggaaa ctttagttgg ttttagtaca
    29941 aaagatatta aaataggcaa atttattaga gtatcttgtc ctatatacta ataagtaaag
    30001 taaacaacaa gctatctttg catatattta tataaaccaa ctattcttaa taaaactaca
    30061 atagtcaaca tgaccactat tatagaatat aataaactaa aaacattatt aacatgatta
    30121 atattatatt ttaataattt tatttttaaa agtaagtcca aaatgttata ttttttgatt
    30181 aaaactgatg ttgatataaa aaattttact taaaaaaaca cttagaaagg ctttataaag
    30241 agcctttttt gcttttattg attaaatttt catataaaat tccttattaa atttcaaatc
    30301 aataaaaaaa ggctctttat aaagcctccc ctatttttat tgattaaatc ctaatataga
    30361 caatgcctta gcatcatagt aagtagtcat ctctcttgtt gcatccttta atttacggta
    30421 atcaaagtct aatgctccac caaaagctga tatttcagac ccatcagacc tataccattt
    30481 cccatcaatt tgtatatagt tccaagcatg atttaatgat ggatttaata tagatagtga
    30541 atccattccc attaaccttg ttaataaatg aaagctactt gcaaaacttc cacatacacc
    30601 acgtttatca accagattac catagactat gttacaatat ttagagtcta catattttgc
    30661 ttcggttacc aattttgcag ctctattagc tctttccatc tcagatgcat ttctccagtc
    30721 aaaactattt aaaaaattcc tgattactgt aagtgtatct tgagcttgtt tgtaagaaat
    30781 ccaatctcca tcggctatta cttctatagg gtcaagtttt ccaaagccta ttctctgata
    30841 tgagctacct gacaatgctg ctgcataaaa tcctagccct tccataccct tatttatata
    30901 ataatattta ccatctgctc gaagctcaac tccatttgga tttcctccat agagtaaatt
    30961 aaacttattt ttttaaaaca tattgtttaa atcagtacat ttatatgttt tttttgttca
    31021 tctgttttat caaatatatt agtctttgaa ttttgtttgt attcttcagc atctttatct
    31081 aacttttcta ttctcgactc aagtttcatt atttcttctt gtgttaaatt tataaaattt
    31141 ttaagcatat tttcaagctc ttcacgagtt ttacctacta aagataagtc ctcagatact
    31201 ttctcttttt tattagaatc ctctttataa tccttttttt gttctaactc ttctaatttt
    31261 tcatcattta atatttcttc ttcaattttt tcattagact ctttagtgat taaagattct
    31321 ttttcatcat ttgtatttag ataagttgaa ttttcatcta acattgtact tttattttta
    31381 tcttctataa tgctattttt aatacctatt tctatattag aaaagttatt agttgtttct
    31441 cttatttctg atttatataa gttcttaatt gcttcattta tttttttagt ataaacctct
    31501 tgtctatatt ttaaatctct aattctatca ttaagttctt gcttttgttt cataatatta
    31561 gataaataag tgtcttttcc tacagtttca tttttcttaa ccatactttc atttattctt
    31621 gtattattta tattactttc atgtctaaat gaatattgac ttctatattg actagatatt
    31681 ttcatttatt tcacctctct aaaataaatt tatgtttata aaaaccaact taacttaatt
    31741 atattttatc atcaaaagta tacatttaca aatattagtt aatagtttta taggttcgag
    31801 cattgttttc aacaaaaaat ttttattata aattaaaaca ataattttta taaatatctt
    31861 atttgtattt tataattcat atatttttac tttataaatt agcaatattg cagttttgct
    31921 cttaagaaac atctctatca tacataagca tatactctat tatgtattag tataaatatg
    31981 ccttttctta tcttacataa gacctcttta taaaggagac tatcgtaaca aatatgtata
    32041 cattatcaca tatatatatc atcatataaa aaatcaaact ttattaaaaa aattaataaa
    32101 ttgctttaaa taataccaca aaccaaattt gccatcaaaa tcacattaaa gtaacaaatt
    32161 aatggcaaat ttaatacatt aatagtatat agactcatag aatgaacaaa aaaactacac
    32221 ttatcttcta atcgtcttat ttatttttga gatattttta aatttctttt ctttttttgc
    32281 taagtattcg cttttattgt ctgcaaatac tgcttcagtt ttaagcctac gataggattc
    32341 ccatctttta ggcgaaagtt cttgatgagc aatagcttcc cagatagcac agcctggttc
    32401 tgaggtgtga gtacaattac gaaaatgaca ttttccgaaa taagcttcta tatctgcaaa
    32461 acttttatct aaaccttctg aaacatccca cattcccaac tctctcatac ctggtgtgtc
    32521 aataacaata ccaccacctg aaattaaaaa tagctctcgt ctagtcgtgg catgtcttcc
    32581 tttatcatca tctatgcgaa tttcctttgt atttaaaaat tctcctccta gcagacaatt
    32641 aattaatgaa gattttccaa ctcctgaaga gccaagtaat gcaacagtac agcctgattt
    32701 gatatactta gaaatctgtt tataaccatc tggctctata gatgaggtaa ctactacatc
    32761 tacacccaag gctatagaat taactacttg taatttacga tgcacattgt cacataagtc
    32821 tgatttagta agtactacta ctgggatagc tccactttcc catgttaaag acagatacct
    32881 ctccaatcta tgaatgttaa aatccttatt cagtgacatg cacaaaaaaa caatgtcaat
    32941 attagctgca accacctgtt cctcatttac ctttccagca gccttacgca caaacaagct
    33001 ttttctatga agcacatgat gaataatagc attaccattt ttattattgc aacgatccaa
    33061 cataacgaaa tcaccaactg tgggaaaatc agattgtata gtagcctcaa aacgcagttt
    33121 tcctgaaacc tctgcaaaca gtacaccatt tacacataca gcttgataaa agttcttttc
    33181 ctgcgagata attcgagcaa ggtataaatc gtgatattcc atactttgag taataaaatt
    33241 cctatttaga ccatagtctt gtaaattgat ttgtttcata ccattcattc tgtttcctcc
    33301 ttttccaact tttcaatgat tctttctagt gggaaagggg gctgtgccag tggttttaat
    33361 gcaattgaca ttaatttcac tgaattatca tcagctgcaa tacgattaga actaagatgt
    33421 ccacagcgtg tacaacgatg aataattgcc cactcaccat tttttctcac ccacactcca
    33481 ataggttcca tattagcatc acaatctgca gcacggtcac caggaatgat atctacatga
    33541 agactatgta aacaatgtgg acaatgattt ctatgttgtg taccagctcc ttcaggaact
    33601 acaaggcaac cacaattttt gcaaataaag ttatccatac aggaattttc ctgataataa
    33661 gctcgttttc tatttttata attcattttt atttcctccg tatcttgtat tttctacaaa
    33721 aaaagtccac aggtatttat atctgccttt ttatgtggta tacatattta cctacacaaa
    33781 aacagaaaac ccctgtggac tagaaaattt agtatcttct atttcaacat aattatattc
    33841 aaaataatac tgtgtaaaat taataaaagt gtagcagatt aaagcccact acaccacaat
    33901 ttaacaaagt aatatgtaat attattattt gttgtctaat gttagttatc tataaaggca
    33961 gagtaagaca caacaatcaa atgtatcaaa aatacactta aaaattctga ttaaacagaa
    34021 cccatatgcg tctccaacta tttatttgtt ggttaccatt atatataact ctgacatcag
    34081 gcaagacact ccttcactaa taattattat taaaatttta tcataaaata taagtatgtt
    34141 caagtataat ttaatatatt catatattta tgtttgtctc attttcttat tctataaaat
    34201 ctagtggtat tttaaaattt aatgttcacc tagtattaat aataaaaatt aattgctatt
    34261 atttgttttc tcattttatg cctattgctc aatttatctc acttaaatta ataacaactg
    34321 tcttttcata caaaacctac aatcaagttt ttccatatat tctacatgaa tagtctattt
    34381 tttttatata aaataacgtt catatttgta aatttattta attttcaaat aagtatattg
    34441 aataataagc aattctattg tattattgta attgtagaat aaaactaaat cggcaaaact
    34501 agagaaattt agtgacgcaa agctataggg actaacgctt ataaaataaa ctatgagtta
    34561 tgtcagccag ttgccaaaaa gagatattct ttttgttttt atgaaagttt tttaggggga
    34621 taataatata tatgtttaga gataaaatgg atagatgtac acatatgttg actgcttata
    34681 ttggtagttc atatgattat tgtgatttta tagatacaca actagatgat tttatactag
    34741 agtacggaga aaatgtggta gaatcttgtt tgcatcaagt gatggtatta gtaagtaagt
    34801 ataattaaat agatttggtt ttctagagaa ccctttttag ttttatctac tttaaatagc
    34861 cttatgttag aaagctaatt aagatagatt tctagtattc ataattttat tttctattta
    34921 aaatacatat aataaagatg taaatttgta tcaaataata aatatgagaa cttaaattct
    34981 cttatctatg tgaaaataaa catctcttaa aatgaaattc tgtaaacata aatgattttt
    35041 tagtttgaag gattagatta acaaaattat aaatttgcaa ataagctata ttaaaaaata
    35101 taataatttt ttatataact tattctttta taacttttaa ttttaaaaga ggagaatgta
    35161 tataagagta ttcaatgtac tagaaaaaat caaaagaaat attagaagaa atggatattg
    35221 agtaatcaaa taaaagattt tgatattaca aatgatatgt ttcaagaaag cattcctatc
    35281 acaacaaaaa ctattcttga agacatgcct tcaaatgatg aattaaatca tgttttttca
    35341 aaaggttgtg aacgaaaaat gaaaaagaga aaaattgtat taatcacact actattaata
    35401 ggtgttttgt tattaggaag tatcctatat aatctttttt tagtaaaagc agctaatatt
    35461 tcaatgctaa aggaatcttg gaattttgat ataccaatac ctaacaaaga aattgaagta
    35521 tttgatactc aagatagtat taatggagat ggacaaagtt attttattca aggattttct
    35581 gaaaagaatt tcaaaaaagt ttttaattta aaaggtggta tagttgtaag caaagataat
    35641 attaatgaaa tagaaaaata tattgataaa tttaaaagag attctgttaa cattaataaa
    35701 agtaataaaa ataaaattga agaagatttt aaaaaatata agttagaagt taaaaaagat
    35761 gataagtata tatataagag aaattatgaa aactatgtag ttttaattat aaaaaaagat
    35821 gaacaaaaat tatacagttt aatatggaat cagtaggtac atatgtatta ttaagaatta
    35881 taaataataa aaataaattt tagtcaatct acaaaaacct tttaaattgt ctggaaatca
    35941 cctcctcatt tgttataaaa acatacaaca aatgaagagg tgattttatg gtttttaaaa
    36001 aaataattat aagtggatat gtgctttcac atgtttatca acatttgtaa tgcctatatt
    36061 tgctaatgaa ttataatata aaaatattaa ataatattca actatagatt atgtaaatta
    36121 tcctatgaaa aaaataagtt gtataaaatc tggcaactgt agattgacga tttcttttaa
    36181 aattacaatt ataataagtt ttatagaatt aaaaataaaa ctttagagat ttttgataac
    36241 attgtagact aaatttgcca ccgaaattac tttacagtgg caaatcggtg gcaaatacaa
    36301 tatattatta gtatataatc tatataaaca ttactattgc ttgattatct tagctacagt
    36361 ttcaacttgc tcatcatttt ccaaacttat attaagatct tcatcaatga taggtagctt
    36421 aaaagtaatg gattttagcc attgtccatt aggctgcttt tcttcataaa tttgaatttc
    36481 tgaaatgagt gcttctatta actgcctgcg ttcaacatcg ttcatgactt tataaagctt
    36541 gtcaaaataa atcaatactt tatatatgtt atcaccagta agtttctcaa cctctatcgt
    36601 ttcttttttt gctttagctt ctattaactg actttctaat tcctcaattt tatcgtacat
    36661 acgataaagc ctatcatcta aatcattttt tcttctctta taatgtttat cctctacatc
    36721 taaattatct atttcctcaa taagcttata ctttgtagaa tgactttttc ttagttcatt
    36781 ttggtaatta tctatctcat tttcaatagc agatgtatca accttcatgt taattttttc
    36841 ttgtatcata gatgcaaatt tagggttgct tactaacttg attattacct cagcaacggc
    36901 atcatctaac aattcttctc taatttgttt attataggta catttatgtc ctctattcat
    36961 aagtctatgc ttacaaccat agtaatagaa gtctttatac ttcgtcccat cttttttata
    37021 ttttatagat ttattcccaa acattccagc tccacatatc ggacacttta ctattcctga
    37081 taataagtgt gtcctcatgt tcttgccctt atttacatgt tcatactttt tagcttgtgc
    37141 tttcagttta acttgtgcag cctgccacaa ttcatctggg attattgctt catgaatgcc
    37201 ttctgctact aaataatcgt cctgctctac ttgtctgtat tcattccttg taccatgaac
    37261 tttttctaaa gttcttcttc caaatgctat tttcccgtta tacacaggat tctttaatat
    37321 ttttcttata agacctgcgt caaacaatgg atttttccca ttttgtcttg gtattttcct
    37381 tataccatga ttttctaaat atttagaaag accattagct ccaatacttg tatttacata
    37441 ttgatcaaaa atagttctta ttgcaattgc ttcttcctca tttattatca atttcccatc
    37501 aataagttga taaccatacg gagcaaatcc accattccat ttaccctctt ttgccttttg
    37561 aatgcgacct tccattgttt ggacacgaat gttttctctt tctatttcag ccactgccga
    37621 taaaacagaa atcatcaatt tacccgcatc tttagatgaa tcaattccat cttcaacgca
    37681 aataagattt actccaaaat cctgcattat ttgtaaagtc gaaagtacat cagcagcatt
    37741 tcttgcaaat ctcgatagtt taaatacaag aacgaaagac actccatcct ttccggattt
    37801 tatatcttcc atcatacgag taaactgaac tctaccttct atagattttc cagacttacc
    37861 tgcatcttcg tattcaccaa caatctcata atcattatag agagcaaaag ccttcattct
    37921 tgatttttgt gcctctaaag aataaccatc tatctgtatg gatgtagata ctcttgtata
    37981 gagatatact tttatttttt cttttgacat agcattaacc tcaatatcct tattatatat
    38041 ttatatattt ttaccaataa aggtttggac tttaatctca agtatattat agcactttta
    38101 tttctctttc tcaatccgtg cttttagcta tatcaaattt attcttatcc tctgtatttt
    38161 ttactggagt aggatttgga agattctcta aatctaaaac tccagcatat tttgtaatca
    38221 gatttgctat caaatcagcc aatccattcc agtcattatc cactaataca cctcctccac
    38281 tttaaattct ttataaccaa atattatttt tcttactaag ttttatgaca ttggtaggtg
    38341 cattggctgc tacataggaa tctcacctcc gccccttgtt tcagacgagg cagcttaaac
    38401 tattgaagta tcattatcac cacttacatc atcgaaataa gctgccacgc ttatctttta
    38461 tgtattccta tctatcgctc attttcttct aacctcggca ttatgccggt attcatttga
    38521 accgattttc atcagcagaa aagtcttggc gtaggtcata actctcagta agtagataaa
    38581 gtcctacctt ggtctattca gttgtcaaag atcaatattt gaaagggact gttttcttta
    38641 cattttccta tttgccataa gcaggcgtat ctcctactca agaaagtaaa ggaggtcaaa
    38701 ctccccttca ctttacataa ggaaaatttg ccccctttgg ttaccaaagt tttaaagttc
    38761 ttcgataaat tttttcagct tttcaagaat tttgtttctt cttttgatta aagccggatg
    38821 tgtaatactt ttgagctttg ctactgaacg aacagtttca tcattgaaat acaagcgttc
    38881 aataatatct ctttcttctg cattgagcct tgttatagca cttcttactg cttcaatcat
    38941 catctgtgtt tcaacaatct tttctacatc aacactttca tcaacaatat tatctgtaaa
    39001 gtgtccgtca tgatccaatg ctgaaaaaaa gagcaagtgg tttttcctgt ccacctgctc
    39061 taaatacttc tcgtgttctt tttctcgcca gtagactata tatatatctt cactgacttt
    39121 taccttttgt cctctgatat aaagataata ctcttttgcc ataaagtttc ctccatctct
    39181 tttttatctg cttgtttttc agataaaaaa ggaggacttc tgcatcttgg cataagaagt
    39241 cctctgaaat gaaagaataa aaatatttct ttatatgaac ttgattgttt caattcgcac
    39301 ctgaaacaat catctactat acatattata aaaaagagga atgtattgaa ttctaaatat
    39361 ttctaacatt aaacgtttag atgcttccat atttatttcc tccattttat caataatcta
    39421 aataaccatc atattcatct actacttata taattgagtt ttattaaact ttttaagttt
    39481 ctattctatc aaatatttaa acagtctctg catccgaaaa gactaactca tatagtttta
    39541 ctaacaatat tttcattagc gtgttcaaat cctgatttct tgtatcaatt attttctgtt
    39601 cactttcaat aagaaaaaag cctttacttc catggctaat aataagtctc tatttttcaa
    39661 taactattgc aaaattatat cttgtttaag aaaatatttt aattttaaag ataaaaaatt
    39721 cttcatcctg caatgcttta tattctatat tgtaattatt cagaatatta cttacaatat
    39781 ataaacctaa tccattacta ttttccttat ttaaatcaaa tttaacatca aatattttat
    39841 ccatattcga aattttattg ttaccgtatg aattctctat atataaccaa tcattaacta
    39901 tcccaatatt aattacccca tttacatcag tatattttac cgcattacta atcaaattag
    39961 atagaataat ctttaaagct gtttttccta tataaacatt ctcatctaat atataattat
    40021 tgacagttat tttcttttga tttgctaata tttcatactt ttttaatatg tcttctaatg
    40081 tatcatttat tttcaaatat tcttcatcat tattcaaatt ttctatagaa tgaactgata
    40141 atatttgaga aatatttttt gttaaactat caacgatttc aatacattca ttaatataaa
    40201 tatctctttc tttatatttt ccaatattgt atttcatgtt ttccagtatt attttaagac
    40261 tagcaagagg agttttaagt tcatgggatg cacctttaaa aaagtcatat tttaactttt
    40321 ctaattttaa aatttcttta tttttaaatt ccaaatcgtc aattgttctt aataaagtag
    40381 aatacaaatc attaatttgt tgttttaatt ctccaacttc atcattagag ctaactttta
    40441 aacgcgtttt tttatcaagt ttcatcattt tatcagtaac aatttttatt tcttgtatat
    40501 tattttttat tgattttgca taaattaaag aaataatagc agaaaataaa attgatatta
    40561 ataaagaata tggtaaaaat ttaaggctta aatctttcgc atctttttgc atatcagctg
    40621 tagaaacaaa ttgtagattt gtttttttac catcattaag ctttatttct ctttcttcaa
    40681 ttatcaaaga attactatca ctttctaaat taacatttat attatctttg atttgtattt
    40741 cattcttatt atttttttct tttataaatg cttttatttc actactctta gaataaagct
    40801 ccaaagtttg ttctatatat tttatttctt ttccattcat attactagaa atttcatttg
    40861 ccatattatg aatcttttct tttctcgtct ccaaatatgt tttaggaaag ataaaaaaaa
    40921 ctaatgaatg aactaatata attattattc caagaacaga aaatatttgt atgaacattt
    40981 ttggaaatat ctttaatttt ttcattttct ctccaattta tatcctacat ttcttatagt
    41041 agttatacag tctaattgta atttttttct aagttctttt atatatacat ctattactcg
    41101 atcataagga gtttcttcgc tatctttcca tacataatca ataatttgca ttcttgttaa
    41161 cacttgtcca ttattatcca ataaacattt taatacttct agttcttttg catttacatc
    41221 tatttcttca ccatttattt tagctgtata gctattaaaa ttaaccgata gatcattata
    41281 ttcaaacttc tctaaatgtc cataattctt cttaattaaa gaatctattc tagcctttaa
    41341 gaccggcaat gaaaatggct tttctacata tccgtctact aaattagtaa atgcatcaat
    41401 tttatattct tcatcactaa atgcagtcaa gattagaatt ggtaaattgc ttttctttct
    41461 aatttctttc aacacttcta aaccatttat aaaaggtatc tgaatgtcta agataaccaa
    41521 atttatatcg ctattaaatt ttgacaaggc ttctcttcca tctttagctt gaataacagt
    41581 atatccaaat tctgaaagat attcacttat tccctctctt atcatattat catcttcaac
    41641 agttaatatt ttcatatata cctccactta agcctctaca cttatattat acagcatatt
    41701 atttgatatt taaaagccaa aaaatttttg gtgctaaaaa gcaccgaaaa ttttaattat
    41761 tgtcaattaa taattctttt ggattccttc ttaatatatt gaatgaagaa ataatcaatg
    41821 atacaagaag tactaaactc ataaatataa ctacataaat tatgaattta ggtaatacat
    41881 ttatatctaa acttgataat gtcttgttaa atccttcagc ttctgcccca ccacctaatt
    41941 ggctagatgc agattgtcta gctatttgtt tagctatatc accagtaacc ttattcaata
    42001 tattattccc aagcttatca gctgtatatt gagctaagaa ataagaacca acgaatgcgg
    42061 ggattgatat aaataccatc tcaattagga attgaccaaa aatttctaat tttgatatac
    42121 ctaatgatag taatactgct atttctttct ttctagcatt catccataag aataataata
    42181 atgaaactac aactcctgca aatattaatg agccaacaaa taatttattt gaaattgagt
    42241 agatacctga tatagattgt tgtaatgcag ggtaatttga tgaactttta atcaaattat
    42301 attctctcca atttatatct aatttcccaa gatcttttat tacactatca agattcttat
    42361 caccttttac aaagaatgtt gcatcttggt atacagctgt atcttctgta ttaccataaa
    42421 ctttagcagc tgtatgaaca tcagtgatta atgtattttc gtatagttct tgtgctgcac
    42481 ttactccacc gctattatgc ccatcgaata gacctttaat ttctacttct actgtttcat
    42541 ctgcaccttt ctcattatca gcatcaaata aattagattt tatttttatc ttatctccaa
    42601 ctttaagatt atttttttca gctaaatctt tatgcattaa gattttattt ttatcttcat
    42661 tttctaaatg ctttccttct actaatttat atgcttctga tacaaatttt gtttcttttg
    42721 atgagtcgtt aaccccagtt aacataactg ttcttttaaa attcttcgct ctttcaggtg
    42781 attgattcgc aagagtctct tgagtttcaa taatatcata atcaactaaa tctgcaacac
    42841 tgtttattct ttttacatag gagtctatac tatctgtttg aaatatcttt ttaatatctt
    42901 caccttttac atttccccca cctctaggtg ttcctggatt tacttgtcta tttatctcca
    42961 tagaaaaact atttgttata ttagcaaatg tttcttttga agctctgtcc gtagcatctt
    43021 taatagataa actaatgaga cttaaagttg acatagataa aataactaat ataataatta
    43081 atgattttaa gctttttcta gttacataag caaatgcatt ttttatcatt attcaacctc
    43141 caaattcatt ttatttactt ttttcaactt tttaccactt agttctaaaa tgatatccgc
    43201 agaatctgct acttccttac tatgtgttac aactattaca catttatttc tatctttagc
    43261 taatgtcttt aatatattaa ttatttctcc agcagtaaca ctgtctagat taccagtagg
    43321 ctcatcagct agtattattg gagcatctga taccaatgct ctagcaatag ctactctttg
    43381 ttgctgtcca ccagataatt tcataacatt tctttttatt tgttttttat ctaaacctag
    43441 ttcaaacaag atactttcat ctgctgattt atttactaat ctaatatttt caattggtga
    43501 taaataatct attaaattat agttttgaaa tactaaagat atattatttt ttctatgatt
    43561 actatatcct ttcttttgta tatcttcatt cttaaacaat atttttcctg tttgaggttt
    43621 atcaagtcca gcaagtaagg aaagaagtgt agattttcct gttcctgact ttcctactat
    43681 cgcataaaac ttcccaagtt caaatttttg atttactcct gacaaaactt tttctttaga
    43741 atttgcataa ctatatgcta cattctttat ttctaatata tccattattt tctcctaact
    43801 tatttttgat aatatttctt taggcttctt gattaatatt aatgaagaag caaatacaac
    43861 tgataaaaca ataatactta ttaatattaa ataactttgt ccaagtgttg ttatatttaa
    43921 cataaaacta ctattattta ttaaacttcc accggaaatc attgagtcct ctgagttaat
    43981 gaatccatct acaattactt ttagtaatac atttcctaaa aataaggaag atattatact
    44041 tggtatcgat atgaatatta actcgaatat aaattgcatt ataatttgta tcttagatgt
    44101 tccaatagat aaaaatatac ctatttcata aattctttct cttaaccata gaatcaagat
    44161 taatgaaaga acaaccatcc cacctaacat aatagaataa gtcattattt ttattatatg
    44221 ttttattcca ctcactgact ctaaagactc ttcaaacgca ttagaatctt tttcaacaaa
    44281 atactttgac tcatcaattt taagctcttt caatttgttt aaggctaagt ctgtagattc
    44341 tgcactacca gaatacatta aaattttatt tgcgatttta ttattttctg atttatttaa
    44401 tatctcttgg cttgttgaat aatctacaaa caccatattt tcactaaaat cagaagataa
    44461 tcctgtatat gtttcctgtt ttttaccaga aaagatccct ataattttaa atttatgact
    44521 ttttattttt ccactttttt caatatctag taattcaaga tcaacttcat cacctaattt
    44581 tagattgttt tgtttagcaa attcttcatg aacaataatt gaattcttat cattttctcc
    44641 tatatttttg ccttctttaa ttgtaaatac tccactacta aataaaatat ttcttttagt
    44701 attatttgta gcttcgagtg aaacaacatt cttaaattcg tcagataaat cttctctatt
    44761 tattctttgt tctccgctaa ctactttagc atcttttagt tttgctaatc catcatattg
    44821 aattattttt tcttcaattt cttttaattt ttcaatatct ttaaattgat taacattaaa
    44881 atatttacca tctttttttg ttattgatat tgaagaatta gaactttcat ataaagcctt
    44941 ttctatttca ttgcttgatt tcattattgt taaacaagaa tacaagcaag aaagaactat
    45001 agttaatatg ataaaaatta ttaaagttct atttctcttt cttgtaatat atgctatagc
    45061 attttttatc actttcctaa ctactcctct ctattttctt actccataac taattgcatc
    45121 cactggacaa gcatttttac atcgtccaca tctgatacac tccagatgat tgcaattctc
    45181 aactggatct atattcattt ggcaaacttt tttacatttt ccacaattaa tacacttatc
    45241 cttatccaat ctatatctaa atattgaaat agggttaaaa attgagtaaa tagctccaag
    45301 tggacatata tatttacaaa aaggtctata tataattata gaaagtaaca aagtaactat
    45361 tagaatgatt cctttccaat aatacaagaa acctatcgca tttctcatac ttttatttaa
    45421 taaaacaagt ggtaatcctc cttccagcat accaatcgga caaataagtt tacaaaaata
    45481 cggagaaccc tgacctaaaa tatcaaccaa aaataaaggt aatattatta caaatacaag
    45541 taatattatg tatttcaatt ttctcaaatg tttatcaaac ttaaatgttt caactttttt
    45601 aaaaaaggga atcttatgta gcaaatcttg aatcaatcca aatggacaca gccatccaca
    45661 aacaaatctt cccaccaatg ctcctataaa aaacaaaatc ccaactatat aataactaat
    45721 cttatatttt gaatttccaa ttactgcctg tagtgatcct attggacaag aaccttttgc
    45781 tcccgggcat gaataacaat tcatacctgg aacacaaatt ttctttaaat tcccaccgta
    45841 gattttacca gtcttaaacc cttcaaagta agaattagta attaaaaacc aaacggattg
    45901 aaataaatgc ctaaaacgat ctcttatttt atatttatct ttttttgtac taccatttat
    45961 aatattttta attctatcca attccaatac actccataca aattcttatc gccttatcca
    46021 agacaacttt agtttctcca ttactatgac catagtaaat catcgccata ctaataaaga
    46081 taattaataa agacaaggca cggcttttta aaaacttatt aaccatatac caatcaccgc
    46141 tttactttta tttatttttt attttttcca attctttttc aattacctgc ttccattcct
    46201 ttgaactctt tgccccagaa taagtatcac ctacaatatt tccattacta tcaacaaaga
    46261 aagtctctgg catagcctgt ataccattca atctaccatt aaagtttgtc ttatctggca
    46321 ttaagaaagg atatgaagcc tttgtctttt catgtattaa ctttgacttt tcaattgctt
    46381 ccttgttttc accgttatca tcaacagtat ctgtaacaac tccaacgata tttacaccct
    46441 tgcttttcat ttcattctga acctcaacca aatcaggaat ttcctttaca caagctgtac
    46501 accaagttgc aaatacattt accatagtaa gatcatactt ctcaaaatct ttacttgtaa
    46561 aatccttgcc atttatgtcc tttgttgata gtttacgtaa atctttaacc gattctttgt
    46621 taaatgcttc tgtattttct aaatcagttt tttctgatag cacaaaacca tttttaggac
    46681 gttctttttt atctataatt tgaatctcag ttctttttaa ttcatccaga agattacttt
    46741 cagctccgct atttgtgctt aaatagcaat cgtattttcc atcacttgaa actcctattt
    46801 tagtatgagt atcacatttt gtaattttag atattttttc ttctgatgta tttttttcga
    46861 atataccaat agtcccaatt ctttcaagct cattttgcca atttttatat ccatcgccca
    46921 tcttttctat aactgcattc ttttgttctt ctgtcatttt ttcaaatgtc aaaatagcat
    46981 actttagttc tttatctata ggactttgat catctaacat cgctatcttt ttatcatcca
    47041 tatacttttt aaatttgtct gaaagtttaa atttaagacc taaatattca taaacatatt
    47101 ctttttttgt ttttaaagta taatctgatg gcttaaatgt ttcattttta tccttctcat
    47161 tagttgacat acctgcctct tcagaactta tagattgtcc ttctttaatt ttattgcttt
    47221 cattactttt tttacaccca actgtactta agctcaaaca taacgtaagt aataggcatg
    47281 ctcctcttga tactattttt ttcataaatt tttcctcctt tattcctcct ttatttttac
    47341 acaatagcag tttataacta ctttcaataa tattctacac accttttatg aaacgttgat
    47401 gaaatataat tttttatttt tccaaactat ggtataataa tataaatatt atgcttaaag
    47461 ttgttcttac acgattagta tatgatcgat tagtatatga gcaagcacag taagtgtacg
    47521 gacacttacg aaaaaattga tgaagcagcc ctctgggata tgcttctttt tttatcaatt
    47581 tttaacttgt tagggtatac cctaagaccc cgaaatacat tcaaaggagg atttacctat
    47641 ggcaaataga atacgaaatg aaagactgga aattaaacta actgaagaag aaaaggctct
    47701 ttttgaggag aaacgaaagc tcgcaaggtg cagaaatatg agccacttta tccgcaaatg
    47761 cgttttggaa aaggaaatat atcaagtgga tttagaaccg tttagagatt tacagggctt
    47821 actgtccaat gctacaagca acatcaatca gattgcaaag cgtgtaaatt ccaccggcat
    47881 aatctataag gacgatataa acgatatgaa aaagcagatt gaatatttct caaaagagtt
    47941 gtggcaaata cattctctgc ttcttaacag aacttctgga ggtgattaaa tcttatggct
    48001 ataacaaaaa tacatcctat aaaatcaacc cttaatcttg ccatttcata tattgttaat
    48061 ggaaaaaaaa cagatgagca aatcttagta agcactcata aatgccatca agaaactgct
    48121 catacccagt ttttaagaac acgaaatgat gttggaacaa acggaactgt tcttgccaga
    48181 caccttattc aatccttttt acccggagaa gcaagtccta aaatggcaca tcaaatcggt
    48241 cttgaactgt gtaaaaagat attaaaggac gagtacgaat ttgtcttatc tacccacata
    48301 gataaagggc atatccacaa ccatatcatc ttcaataatg tgaatatggt aacaggcaag
    48361 tgctatcaat ccaacaagaa aagctaccac aaaatcaggt atcaaagcga taagctatgc
    48421 aaagaaaaca acctttctgt gattgatgag ttttacgaaa gctataagag aaagtacaaa
    48481 acaaatggca agtcatggta tgaaaatgag caatctaaga gaggtacttc ttggaaaagc
    48541 agacttcaat ttgacattga tcgtcttata aaacagtcta agtattggga agaatttcta
    48601 aaaaaaatgg cggagcttgg ttatgaaata aagtatggga aacacatagc ctttaaacca
    48661 aaagataaga caagatttac aagagctaaa acgattggtg aggactatac agaagaaaga
    48721 ttaaaagagc gtattacaga aaatcaatct attacaactc cacctgtcaa aagacgaatc
    48781 ggaaatatca tcaatatgaa tgccaatgcc aaagtgaaag agagcaaagg ctatgaatat
    48841 tgggcaacca aacataactt aaatacaatg gctgagtcag ttatttttat cagagaacat
    48901 ggcattaact ccattaagca gcttgataaa tacattcaaa aaagtgctga agaaagacaa
    48961 gacttacaag ataaaatgaa agaaattgac aaggatatgc agctactttc cgatacaatg
    49021 gagcaggttc atactgttaa aaaatatcga gcctactaca aagaatataa agcaaaccct
    49081 tccgataaag cattttttga ggagcataag gctgaaatta cacactatga aatagctctt
    49141 tcaaagctaa aaaaatccta ttcaaagctg ccgaattcaa aggatatttt agataaactt
    49201 aataaactgc aagaaaaaaa gaataccctt attcaagagt attcttctac aaaatctact
    49261 atggacgaac tttatcaaat acgaaagaac tatggaattt acatgggtaa ggagatggaa
    49321 cgataactct aatattatat agctttctta tttttataat attaaattga aatgcctatc
    49381 aatgatgcaa gcatttttat acctaaagct aaatcaggaa ttaaagctac ggaagtagtg
    49441 ataaaatgca tactttttaa acaagtagtc aatacttctt tcttcggatg cttctgctta
    49501 atttcatttt ttatattatc taaattctga ttaagtattg atttggagtt atcatcctcc
    49561 atacctttaa ttaagtcttc tacattgtta attgccttga ttacttcttc agtattaaat
    49621 ttattttctt ggtcagcgtt aatcgtgctt ccgtgttccg caatattgac ttgaactcca
    49681 gaactattaa cattgatatt atatagagca ttattttcat cgtaccccat atcggtagaa
    49741 atatctttca tataattttc aacctcaagt acaaacggat agaccattct atcgccaaac
    49801 gcctttgcca tatcttgata tttattactg ccagcataat accagccaaa agtatatgta
    49861 ggtagattat ttcctgttat aaaggaaaat gctctataca gtagatacgt ccttttatta
    49921 ctatcattgc caagattcaa aactttacgt ccataagaat tacttatcgt atttaataag
    49981 tcatctaagc catcaacatc atattctaaa ctatgcaaat actcttttat caacaatgtt
    50041 tgctctatat aatttatcat ttcttccaaa tttgcattct gttctccata atatgaattc
    50101 ataacatttg aagctaatat cctaaatttt ctactgattt ttctaagttc ttttttacta
    50161 atctccatct atcatctctc cacaaaacgg gcaataacta ccttctaatt tttttatact
    50221 acttattcta gcggttttgc cacaacacaa atatttcttt tcttcataat ctccagtttt
    50281 tcttcctatc ggaagttctg cttccttttt aatctctttt ccacgtttaa actttatact
    50341 tttactattc ctaaaacttt tttcaagatt ctttgaaaaa tcatttagca tttcagcaac
    50401 ttgattttca actattcgtt ctgctaattc ataaatatca tcgtctaaat aattctcgtg
    50461 tgttaaacca caattaggac accaaatatc tattgtgctt tcagcctcaa tatcttccac
    50521 cgttaacata aatttttcac tacaacttgg acattttaat tgaacatatc cctcttcatc
    50581 cgctggaaca gaaatttcaa attttatatc attagccatt taaatttcat ctcctcacaa
    50641 taaaagttat aatttcacca ctggtagact acaaggtcgt gcatctttac gtacaataac
    50701 aacactattc tcagcacgtg taacagcaac atataatcta gccttacttt gttcttttag
    50761 agatgtgtta ttgttaataa tccaatccca catcggttga gtcggatata taagtactcg
    50821 ttggaattcc aagccttttg attctccaaa attataatat ggatattcat tattgacgga
    50881 tgtcctttta ttttctctca actgcattgc attaaatttc tgcaaatact tctctacatc
    50941 tgctttatca attatcataa caccatctga ttcatcttca gctctacgca caaaatttgt
    51001 agatgttctc tctggataca gactattcgc aaatttacat ataatatcat tgtttctata
    51061 agtacaatta agtgtcgttt catcaattct tacatctaat tttctgcact cattttttaa
    51121 aaactcatct attttcccac aactatattt tttatatttt tttgatgagt gagttgaata
    51181 tgtgcattgt ctaggatccc cgaccattat cacttcaatt cttgaagcta ttaaacactt
    51241 taatatttcc aaatcatacc ccaccatatc ttggacttca tcaacatata tacagtcata
    51301 cattccactg attctttcaa aaacttttcc attacattta tcatttaact ctacaacaca
    51361 ctctgataat ttatcagtat ataccctgtt atctttggca aaatatttgt tggatgtttt
    51421 ctttacgtac gtattgttct gtccatttac aaatataatt ccttcaattc gttccttaaa
    51481 tctacttcct tgataaggtc taataccatc ttttaacaaa aaagaaaacc atgtagaaac
    51541 tgtaatatta ttaggaatta caccaacttt attcttaatt cggctaatta tttgttgctc
    51601 atttgtaata gtatatgtta ggattagtat ttttttatga gtattaagag aatcctctat
    51661 aatttttctt gtttttccag atccagcagc agctatatat aatttcccac tcatattaga
    51721 ataccctcct ttatatattg tggaaattct atagctttat cactttcaaa aatctttaaa
    51781 gcaacttctg ttttatgccc cttcatatat ttaagtaaat catctggatc ttcatatgat
    51841 ttattcaata tctcgtttaa aatagacatg gaattcgatc tatatataca cggttccaaa
    51901 gtattatagt tgtaattttc caaagaacca ttatattcat gggtactatc atcaaaatat
    51961 atatttatat tctcacaaca attatctcct aaataatcgc tatattttct atttagtgca
    52021 tcaatatttc catcattatc ggttatcact gacacacgta attctagcaa ttttgcgatt
    52081 tccaaaaatc ttaaaaaaga aattccaacc gatattatat ctattccatc attaataggc
    52141 aatttaccat tatgagagtc catatatgct ctttgaacaa ttagttcgtc cgaatcacct
    52201 tcgactaaaa ttgctttatt tgataataat aatcgtaacg tatcataacc tgcaattctt
    52261 ttaaaaaata aatttgtttc atttgataaa tcacctagcc gtagtgtttt tcctcgattt
    52321 agtaaaatta aattttcaag tcctaattta tttgatacaa aactactatg cgtagtaact
    52381 attatctgtt tttcttttac tgactcattt actttatcta ggagaatatt taagtttgaa
    52441 tatgacaaat ggcattcagg ttcttctaaa agcacaatct gcttattttc tattttatga
    52501 tcacttaatg ccaattgtgt tttaacaata cattgtgtac ctttaccaat gttattatat
    52561 ggtatttcat ttaattgggt taccaagctg ctttcccatg aagttttcgt accgaaatct
    52621 acagaaattg tcaattcgtt atttgatgtt tccgttaatt ttctatttat attagcaata
    52681 ttctcatctc tagaaaattg ttctttcata agcctatgcg cttgcgatat attaataatt
    52741 tcattatcat ctaacagatt ctttactatt ctcgatatgt atatatctga cccactggta
    52801 ggagtatagc ttgtcgtatc aatcattgca gacttaattg gaatgctcct tgcagttata
    52861 ttttctctgg caaaagacat ccaacttacc tcataatatt caattggcaa cgatgttatc
    52921 ttgttcttac aaagcatttt atactcattg ctatattttt catcaaaact aattgataaa
    52981 caaatcccag gggtgtcttt agttttttca gaatttccat cacctaaaaa acttggcatt
    53041 tctgcatcaa aatacgcttc aataattatt ttaggaggtt ctacattcac tccttcgttg
    53101 acttctctaa tatagttttc cactatattc ttattgaaaa ggtactgagt aagttcattc
    53161 ctaatatttt tcccatgata agttccagtt aaaaccagat taatagcttc caaaattgta
    53221 gatttacctg ttccattatt gccaactaat atattaatcc cattttcaaa atcaactata
    53281 aaccaatctg aaaagcattt aaaattcttt atttttaatt tcctaattga cattttatcc
    53341 cccttcttta tctaatataa aaatcatgat tttagaatat aaatattgat aactatataa
    53401 atacagttat gagtttcctg tttaatcaca atcataaatt ttttatgcta catcccttaa
    53461 tattttttca agcaataatt taacaataag ttttatgatc ctctagctcc tgaaaataaa
    53521 tctatgactg taaacttaga ctcccattct ccttacatct tcaataatta cgcactccat
    53581 aatatcttca atatcacaat ccaaagcatt acaaattcta agcaaaacat ccgtagttac
    53641 attctgtcca ttcttcattt tgtaaaatgt acttttactc acttttgcct tttccatcaa
    53701 ttcattattt gtcatatcta aatcaatgag ttttttgaac aatcttttat aactaaaaac
    53761 cctcattctt atcctccgtt caagaaaact atatctagta tattatacca caaaatatac
    53821 ttttttcata aatatattct ctttaatcga acttgcataa ataaaaaaga gccggtgcag
    53881 tcctaagacc acaccgaccg taaatttatc tctcagcttc tttgcttgct tctttctttt
    53941 ctttcggttt ttccttatct tcagcctgat attttttgat agctccaagt atagattctt
    54001 tcttttcttc ctgtcctttc atctgttcct ttgcctttaa cagttttgaa gaaagtatcc
    54061 tgatattgct atgctccttg ccgttatcat caatggaagt tctgatctgc ccaaagagtt
    54121 tgacaaaatc tccctgctta aagtcctttg gaatatcact cttttctcca taaacggagc
    54181 agttgtgata taacttattt ccctcatcat ctttagatac tacggagaag tttgctacct
    54241 taaaggtttc tccgttctta ttttcccttt caattacatc aacttctcca acgatatttc
    54301 cgacaatatt gataagatta tccttttctt cccgaacata aagcaggtct tttatctgcc
    54361 cctgtcccct taaatcctca atcatatagt caaactcctc atgcagcaaa ttaaggctat
    54421 cattgtccat ataagcgtca tatagcttat ctaaagcact ttcatcattg ataccctttt
    54481 ccatgcttat aatcgcttta acaaagtctt tatgattatc acttaacata tcttcaactc
    54541 tatctctcat tgttttgtaa tccatgtttt tatctccttt catggtaaaa gggaggttgc
    54601 cctcccttta tcttaaaaat tcctgctctt ttattttttg tttttcttct gttttacttt
    54661 cttcctgata ggctcttatc tgtcctaaga tagacggctt atcatctgat ttttgtgtgg
    54721 tttcttcttt gctatgaaga ttgtcctcca catcataagt tgactcaaaa taatcactgt
    54781 ccttaaaatc actatcatat ctatccggaa taccgtcatt atcaaggtct tttgcaaacg
    54841 gatcatagaa gttaccctca tcgtcaatat caagtcccgt tgctactctt aaatcttcag
    54901 aatcaacata aaccaaatca ctaaatgtag ataactcaat ttcatttttc atatttctta
    54961 gagcttcatt ttctccctta ttttcataat caaagctctc tgttttaata ggcgtatcat
    55021 caatgtactg tgtccaagtt ttctcctcta aattaagctc atattgaata ccatgtcttt
    55081 catccggtgt attggtatag gcgataccga tatgctttaa gtcaggatat agagtatgaa
    55141 actcatcata actgtgattt tcttcatact ctctgttaca gaagtcaatg attgctcttt
    55201 ttacatcttc cacaagagga ttatcatttt tcttttcttc cacctctccc atatcgagca
    55261 gcttatttaa ctctgcaagt cttaatacct tagttttcaa ctcatctgcc ttttcaaaag
    55321 gcttttttaa ttcctctttg gcattttcaa gctgttcttt tgtacttatg agcttttctt
    55381 caagcatatt tagtttctcc ggcattttct caagggcatt atccagtctt gtgatattac
    55441 cgtccgcact tgttccaagc tctcctaaat gctttgcaac accgtttaag ctgaaattat
    55501 gagaattagt aaagaagtta tagcttacct ctaaatccat atttctatac tttcctataa
    55561 ccttgctttc attgattttt acctttgaaa tagcttcaag taatctttct ccggctaatt
    55621 tcttatcggt aattttttct cccgcaatgg taatagaagt aaacttttct tcaccttccg
    55681 ctttaggctc tacattggat atatcttttt tgacagcttc tatgagcttt tctgttcttg
    55741 cgatttcttc aggatagttt tttgccacct tatcctctaa tctgtaacgg ttagacttat
    55801 agtttgcttc aagcatttta agttttgtaa cctcattatc caaatccatc ttttctttaa
    55861 tctttggatc acccgttgcc aacgctttaa tttcggcgta atttaagctg ctttcgtcca
    55921 catcttctgc cacacgaaca ggagtcttac tggtcataat ctgtgaaatg aacttttgct
    55981 tattctctat cgtctgccaa aggtaggcat caaaggtatt ctctgtaaca taacgataga
    56041 tatttacctt ctcattttca tttccctgcc ttacaattct acccgcacgc tgttcaagat
    56101 cagctggtct ccaaggcaca tccaaatcat gaagtgcaat cagtttattt tgcacattcg
    56161 ttccggctcc catcttctgc gttgaaccca ttaagatacg aacttcgcct tttcttacct
    56221 ttgcaaagag ttcatccttt tgcttatcag aattcgcttc atggataaag gcgatttctt
    56281 ctttcggtat tcccattgct acaagttttt ctctaatatc atcatagata ttaaattctc
    56341 catctccttt tggagtagac atatcggaga aaagtagctg tgttgaccta ttttcttttg
    56401 tcttatccca aatagcaaat acatttttta cgcatacatt tactttacta tcagggttat
    56461 caggaagtag gggattgatt aaacgctgat ctaaggcaag tttcttaccg tcattggtaa
    56521 tcttaagcat attatcaaca tccggctcta caaccctatt tctgacatca tccgctcttt
    56581 cagaaaggct ctttaggatt tccttttgtt cttcagaagg ctcagtttta ataacttcat
    56641 aattagcttc aggtgtagga aggttaagca tatccgcagt ctgaatatct gctacttcct
    56701 tgaacatact cattagttca ggcaagttat agaactttga aaatctcgtt tttaccctat
    56761 atcctgttcc ttcaggagat agttcaaagg agctttgtgt ttctccaaaa gtggaagccc
    56821 aagaatcaaa atgctctaag tgatttttct ttaaactctc atactgaaga tacctttgca
    56881 ttgtataaag ctctgtcatt gagttactta caggtgttcc tgtggcaaaa actatgcctt
    56941 ttcctcctgt catttcatcc atatatctgc atttcataaa catatcggag gacttaaagg
    57001 cttctgactg cccgatacct gcaacatttc tcattttggt atagagataa aggttcttgt
    57061 aattatgtgc ctcgtcaaca aagagcatat caactcccag ttcctcaaag gtaattacat
    57121 cgtctttctt aaaatcatca tttaatttct caagccttgt ttccagtttt ttctttgtct
    57181 tttcaagctg ttttactgta aagttctgat ttctgtcatg cttgtattct tctacatagt
    57241 ttacgatttc attaatctga tcttggatgt gcttttcctg atattcctta ctcatcggga
    57301 ttttttcaaa ctgcgtatgc ccgataacaa ccgcatcata ttcccctgtg gcaatctttc
    57361 cgataaatct ctttctgttc ttcggttcaa agtctttttt atcagccacc ataatattag
    57421 ccgacggata tagctgcata aattcacgac cgatttgtcc tgttaagtga tttggaacaa
    57481 caaacaaaga cttactgcac attccaagtc ttttactttc cattgcggaa gctaccatct
    57541 caaaggtctt tccactgcct accacatgag caagcaatgt gtttcctcca taaagacttc
    57601 ttgctatggc atttctttga tgaggtctta aatcaatttc tgtattcatt ccctcaaaag
    57661 aaagattgct tccatcatat tctctgtttc ggattgagtt aaaacgctca ttatacagtt
    57721 ttacaagacg gtttcttctt tcctgatcgt taaatatcca gttcttaaat tcttctttta
    57781 atagctcctg cttttgtcct gcaagcatgg tttctttttt atttaagaca gaagttttag
    57841 aaccgtccgg atttataatc tggtcaaata cctttgtttc tttaagattt agggcatctt
    57901 caatcagctt ataggcattt acccttgatg taccaaaggt catttctgca aggtcatttc
    57961 ctttatccct gctttttccc tctacattcc attcacttgt aatatttgaa aatttaacct
    58021 taatatccca tcttgcatat cccggagttt ttaaagtttc aaagatgaat ttttcaatat
    58081 ctttaatcgg tatccaagtc gcaccaagac gcacattgat ttcacttgct tctaattcct
    58141 ttggaagaac tttggtaagc tctgcttttt gatattccaa acgattcatt tcatagctta
    58201 tcagctcttt ttcttttcca ttctcaacaa agccaagatg aggaagctct cgttccgttt
    58261 gtcttaactt tgcaaggtag ctgtctacaa tggcaatctt atctctaata tttccgctta
    58321 ggtactcatc ctttgttaca tagccgtact tatatgaatt actgccgttt gcacaagcga
    58381 aaggcaaatc tccatcttca aggttaaagg ataatggtct ataaaagttt tgttcttctc
    58441 tgatgtttag ataaatttct cctctaagtt cttctatcaa agttggtctg tctttacctg
    58501 taaggctttc catatactca aaatccacat agcctttttc agataccgat aagacaagag
    58561 cttcaaggga agtgtccaca tggtctatga ctttggcttt tgtaatggtt ctctttgaga
    58621 aaatatcccc ctttgccttg acgttttctt cttcatcaag aatttcaatg gaagatacaa
    58681 gagggaaatt gctatcctct tttaaggctc tggtattgct taaattattt ataaagccat
    58741 gcttctttga aaagttgtca tagacttcat taagcttttc ttgagctttc tttacctcat
    58801 catcggaata gtcctctttc tgcttgtaga taacatcttt aagggcagta ttcagttcaa
    58861 gatagtcctt aatcttttcc ttattcttat ccgttatctc tttcttgatg aaaagggagt
    58921 tttctctgta atagacttca tcatcaataa cggtatagga aaagtttttg acatcatccg
    58981 ttgcaggaat tgaagtgatt tcatcatcta aaagctctat ttcttcataa gttgatcctt
    59041 tggatatttc ttcacttgct tttgtcagaa gctcttttaa gtcggcattt tctttcggca
    59101 ggcacgcaag tgtgtttcca aatcttcctg aaacttcacg cattgtgccg agtacctgct
    59161 caggatgatc tacaaaatat ttgttatagg taagaccatt ttcatcttca gcaaggtgaa
    59221 tccagtcctc atctctttct ctgatactgt cccttttctt taggaatata atatctgagg
    59281 ttacttctgt tccggctatg cccttaaagg tatcatttgg aagtctgatt gcccctaaaa
    59341 actctgctct tgctgcaaga tagcgtctta cactttcatc ctttttatcc attgttccac
    59401 ttgatgtgat aaaggcgata ataccgccgt ttctgacttt atcaatggat ttcgcaaaga
    59461 aataatcatg gataaggaag ttatttttgt tatactccct gtcatttacc ttatattctc
    59521 caaagggtat attgccgata accgcatcaa agaagttatt ggaaaaggag gtttcttcca
    59581 gtcctttaat ctgcacttca ctttcagggt atagtagttt tccaattcga ccgcttaccg
    59641 agtcaagttc tatgccataa aacttggact tattcatttc atcagggata ttgcctataa
    59701 agtttccgat gcccattgat ggttctaaaa tgtttccctg tttaaatccc atatccgaaa
    59761 gcgtcttata tattccgtca attacggttt tcggtgtata aaagctcgtt aaagtagatt
    59821 ctcttgcagc ttcgtattct gcatgtgata agttctcatt tagaaaagcc cttgcttctt
    59881 tccactgacc ttccttgctt tcatcaaaga cttcggaaag tccgccccag cctacatacc
    59941 ttgctaaaac ttcctgagct gtactgtcaa gctctctttg tccgctctcc actctgttaa
    60001 gcatggaaat tgcttcaagg ttattattta acctttcgct tggacttaac ttttcaggga
    60061 gcgtttcttc tgtaatttta aagttatgag cttccgcttt ccttatttga gtttcctcag
    60121 tagtctgctc tggctgttta tatgtcaggt tttcaaatac cctctcaagg tcgctttcca
    60181 gacgataagg aatgacatcg aagcttgtta tcatcccgcc aaaatactcg gtgttgtcct
    60241 tcaccgttac cgtatttagg ttctttctca tatcatcaaa gcgtgttatg gtatggtttt
    60301 tgtccttgta tttaacttca tcaccgacaa taaagttcgg tctttcaaga cttattttat
    60361 tcagcaagtc ctcattatct gtaaagtcta caatcggaat ttgatggttt ccacttctta
    60421 ccggatcaag ccacaaatca tatcttcctg tgatttcatt tttagaaatt tctctgactt
    60481 tatattcttc atgattaaaa tagacggtat cgcctgcttt aactgcaaac tcttctaaaa
    60541 ggctgtcctc tttttcattc agttctactt cttctctttc tttgaggtaa tcaaataagg
    60601 tagcttgaac tgtgccacgc tttgtagctt cttctgtttc ttcaggtgct tcaagctcta
    60661 ctttatcttc aaagctaagt tctccattaa agacaaactg aagctcctgc tcatccattt
    60721 gttttataag ctctatatct ttaagttctc taaaggtctt tggaaaatcc tctaaaatga
    60781 gcctctgggc atttaattct ttcagttcct caaggttaaa atatccccat tcaggctcta
    60841 ttccaagaac aagtccaaag gcatcaccgc tttccctgtc atactccgtc atataccaag
    60901 tccaatttga acgaaaagga ataatatatg ctgcatgaac ctgcttatcc gctaaatcta
    60961 catcctcctg tgcgtaaatc tctggcactc tttcaagaat ttcatcaggc attagatttc
    61021 caggatcatt tttagaataa tattgcggtt cttttacttc ttctatctct gccgtacttt
    61081 ctgtttcctt ttcctcaaaa taaagttttt tagaaagcag ctcatcaata tgctttgcaa
    61141 cacttgtcca agtaaggaac acatcattac aatcattctt ctgtaattta aaaccctttg
    61201 catcgtgcca ttcatcactt cccattgcac ctgacacaac gtgagaatgt cctccgattc
    61261 catattcatc ttttaggaaa ttggcttttt cctgcaaagt atgattttct ttaaaaaact
    61321 tggtgattcg ttcttttcct ctatcaacgc cgcttcctct tgaaaggctt tcaaggactt
    61381 catcttctgt aataaagagc tttaccttcg gaagttctgt cagattggta ctatattcct
    61441 ttcgttgcag ctcaagttct tgcaacttct gataaagact atctaccttg tgataatgat
    61501 accttaatac atttctgctt tctttgtatc cttctaaaaa cctgctatat tctttgattg
    61561 tttctttcag atattcagga ttttttaatg cttcagataa tcttttcgtt tcttgcggaa
    61621 agccaccacc tctttcaaaa gagttgaaat atccttgctc tattccttct tcgcttaaat
    61681 cgtgcgttag ataccataag gattctgaaa ttctatccct ttcatagtcc tgtgcctcta
    61741 aaagttctac atttgtagca aactcacctc tgtcaagaag ttcatttatc ctacttgctg
    61801 catcactcca acttaaaatt tgtgtattat cctctcttgc cgatgttcca taagctaaat
    61861 gaataccttt atccgaatac caggaagata cttctctttc atcaatgtaa aatccgtttc
    61921 cgcctttaaa ggtatctttg aggtattctc ccaattcttc tatgctcttg ccttttgaaa
    61981 actcagcaat aacaggaagc ctaccgccat catgatttcc tccgttaata aggacggtat
    62041 ctatatcctt ctcagttagc ggaatagtaa ggcttatctg tccataagaa ttttcgggta
    62101 aagaaaaaga agccttttca gcttctatta tccctttatc cgtattgtct tttaaatctc
    62161 cactacttcc ttgatggtca tttctttgag agctgaaatc atcgccccat actgcggatt
    62221 gttctcgtcc tctatcttcc aagctgctat caactttggc ttctctgctc tcataaactc
    62281 tactgcctgt ttctgaatat ccatcaggtg tcctgtcagc ttcttctcct tgtatagatc
    62341 caaaagcatc tcgaagtggc tctgctcctc gctctgtgaa aggtaattca gcctcatcac
    62401 tgcgtaggtc ggattcggat acttccttat aaagtccgtc tgttcctcca agctgtttag
    62461 cgtattctcc ctgatttttt ctattatctc gtccgtactc tccatttcgg agaactcgct
    62521 cgttttcatt tctttcctga tcatctcgtc gaaatacatt ttcttctacc tcctctaatt
    62581 cttctttaat tttattatat cccgcttctt ttcctattaa aacttctttt tgaagctcaa
    62641 gctctttgct tttttgaatg gtttcatcaa taatctttcc gctaatatcc gatacacttt
    62701 caccaaggct cattaaggat atgctgtcaa atctttgaaa attttctctt aaaagctcat
    62761 aatccatcgg ataatctaac ttaaatcttg aagctaccgc atagcttacc gagtccctta
    62821 caaacttggt aaatgatatt ctatcctcat ccgctactct aagttcattc attaaggtat
    62881 ctattttttc atcaccgtag agtctgctta aagaaaagat gttttcaagt gtgctttcac
    62941 tttcctcata gccctcgctt tttatcattt cctttaagac atcttgatgg gcttctttat
    63001 caaatctcca aagattgacc tcgttgacat ccctgttttt tgaaactgtc tggcttatat
    63061 caaagatata gtccaccttt ttatatgtgc cgtaatcctc taaaattggt atccctttct
    63121 gccctcgcat aaccgttcgg ttaaagcgtt ccctccagta gtcgaacttg gcacaggctg
    63181 tcgcttcagg atttttatca tatatactta attgacttct aaaatcatac ctttgattgt
    63241 ttccgacaac ttttaggagc tttagatatt ctgcttcatt atacaaaaca tcttgtttta
    63301 ttagctccaa aatgttatga aaatcattta ttcgcatttt tacctccttc ttttttcaaa
    63361 caaaaaaggc ggttagattt tactctaatc accttcgcta tataccaaat attattactc
    63421 tatttcaatt ttttaattga ttcactttca gatagtatct tcatttgttc aatagctatt
    63481 gcatttaatt tttccaatct ttcagattgg ctcatgcctt catttataaa taccgcatta
    63541 agattctcaa gattagaaag gcagacaagc tgtgatatat ccgcataatc tctaatattg
    63601 ccttttaaat ccggattttc atcacgccac tccttagctg ttattccaaa tagagaaaca
    63661 ttaagaatat ccgcttcact tgcataaata aaattgattt tttcttttga aagtttatcc
    63721 ggtacaagtt tgtttttaat ggcatctgtg tgaattctat aattgatttt tgccaaattt
    63781 ctcttaatat cccatcctaa cttcttttgt tcttcttcct ttaggcgttc aaattccttg
    63841 attaaatata atttaaagta tggcgatacc caagaagcaa actcaaacgc tatatcttta
    63901 tgagcataag ttccaccata tcttcctgct ctcgcaacga taccgataga attagttttt
    63961 tccacccatt gcttgaccga taatataaaa cggttaaatc ctgcttcatt tttaattccc
    64021 tcgaattcgg gggaattaaa attcgtgtta tacatttctt cccaaatacc taaaaactct
    64081 attgtattct tgtttctgag ccacttttca atcaaagcag aaccgttctc aatatttcta
    64141 accatatccg ttaaagaaat ataatctcta ttgtctatgg caataatgct gatttctgaa
    64201 ccttcaacat ttattttaga catataatca cctctcaatc attaaattga ttactttgca
    64261 ttatagcatt tttagagcat tttttccacg ctgaaattag tgctgtctta cttgcgatat
    64321 gtcaaaaccg cttcttttat ctcattttca atcgcatcta aaaattcttt cttagaggat
    64381 ttaccctgag caatatcaga taattccatt tcccactttg ctgtcgtttc tgccgactta
    64441 aaggtatctg ctacaatcgt tacaaggctg attcctttat gcgttgcaat tagattcttc
    64501 ttatctcttt cgacaaatct cttaaagatt agattttcaa taattcctgc ccttgttgcc
    64561 ggagtgccaa gaccttttct ttccacctct acaccttttt ctaaggcatc atttcccgca
    64621 atctccatag actttaagag cgtatcttca gtaaagtgtt tcggaggttg ggtaaatttt
    64681 tctttaacct ctttattttc aacgctcaaa acatcaccaa cacttacatc gggcaataca
    64741 gcatcttcac tcttttttga tttgtattct ttaaggtatt tgctaaagcc ttcatcctta
    64801 attaccttac ctgaacttgt aaattcaaaa ccgtcaaatg aagctacaat ctttgttgta
    64861 ttttcaataa gcggatagcc tacacttgca tgaaatttat cggatataag gaagtaaact
    64921 tttgcttcac ttaaaggtaa ttcagaaaca tcttctttta ctgaactgat tgtcggtatg
    64981 attgcatgat ggtccgtaac ctttttagag ttaaatacta ccttgatacg ctctgtatca
    65041 aagtcatttt tacccaaaat gttgttgact gtactcacaa tcatatcctc tgttaaacat
    65101 ctgctgtctg ttctggggta agtaatcagt ttcttttcat acaggctttg agtatagtca
    65161 agtgtctgct tggcactata tccaaaatat ttattgcact ccctttgaag cgtagttagg
    65221 tcaaaaggta aatcaggctt tgtaattttt tctttttgaa taacatcagt aatttcaatc
    65281 ttatcgccta ctaaacttat aagctgttca gcagcaactt catcatcaat tctgtctgtg
    65341 gagagtgtaa atccattcat agaaagctct actgtgtaat atttttcttt ctgataattt
    65401 gctatctcat catctctttt tacaatcatg gcaagggtag gtgtctgcac tctgccaaca
    65461 ctgtaatttt gctgatacag acaagagtag agcctactaa tattcattcc gactaaccaa
    65521 tccgcaatag ctcttgcctg tgccgattca aagagattat catagtcttt tccgtctgtt
    65581 aggttatcaa aaccctcttt aatggcacta tcttccattg aagaaatcca aaggcgtttc
    65641 atcttctttt tacaattcac ttgattatat acaagtctaa aaatactttc tccctcacgc
    65701 cctgcatcgc acgcattgat aaccgtatca acctccttat cattcatcag ctttttaagg
    65761 atgttaaact gcttcttggt tgcctttgct acttcatact tgtagtcgct cggaataatc
    65821 ggtaaatcag ccatattcca cttggcgtac ttttcatcat aagcatccgg atttgccatt
    65881 tgaattaggt gtccaacgca ccagctcacc ctatatccgt ttccttcata atatccgtct
    65941 ttctttttat ttgctccaat aacctttgca atggagattg caacactcgg cttttctgca
    66001 ataactaact tcatctgtgt tttcctcctg ttataaatca aaatagggcg aaagatgtta
    66061 ctctcccgcc ctaactttgc acccaaaata atatgttttt aggtgcgttt attcttcatc
    66121 ttctacttca tctgcatcat ttatttcttc ctcgctttca gattcagaaa agaaatcatc
    66181 atcttcctcc tctaaggctt caagttcttt atcttctttc tttttcacaa ccttaaaata
    66241 gtagcctgct cctaatgcac cacctactac aagaagcaaa ataatatagg ttcctaaatt
    66301 actcttttcg tccttcttct caggctttac ttcttcctta acaggttctt cttttactac
    66361 ttcctgcttt ggtgcttctt ttttctccac catgttaagc aaatcatctt cagatacttc
    66421 cgtaagaagc attacattct cactatcttc atcatgattg atgattaaat gaaaagtctt
    66481 accgtttttc gtttgaaagg taataaactg ccttgcatct gccgaatact gatccgtttc
    66541 tttgttatcg ctgctatctc catgatgaat cggatactcc ttatttgcat tatctttatt
    66601 ctccgtaacg gatgctctcg cctttgacgg agatgaagct actcccttgt tggtgtttac
    66661 actcttactt gcagacccca ttgatgaatc ctgactgtta ttcgcaggag cttttgccgt
    66721 caacttattg ggatagcgaa cttccttttc tttctccttt acttccgttt tgcctttacc
    66781 ggtatccttt gtagtattac ctgagcttac cgaatccgat gagcctttac cggtactact
    66841 tacagaagtc tgtggtgttt gaggagaaat acctgaactt gtcttaattc cggaaatagg
    66901 actaatcggt gtaactgatt gtgatgttac aggagcttta tttgtttcag ttgccttttt
    66961 ctcaagctct ttcacctttt ccgtcagctt atctatttcc tttttcatat cttctgataa
    67021 gtccttattt cccttatctt tcttcatttt ttctttcagg ctatcaattt catcttcaag
    67081 gtctttaatt ttattctttt gcttatcact taatttgtct ttgtccttaa gttcgcaatt
    67141 taacttatca agtttatcct gaagctcttt tgcctctttt tctatttttg aaatatcgtc
    67201 tttagaaagc tctgtctgcg ttcccttatc ttctgtctga gtgcattcat cctgctttgg
    67261 cttttcttct tccgtctgcg tttccttatc cttaacctcc atctttgcta ccttacggat
    67321 aatctcatct tttccatctc cctttacctc ataaaacaga aattcatcaa tgaatttcat
    67381 atcatctggg agcattggaa gatctccgct atcaataagt tgtcctttct cagcctttat
    67441 cttttcttcc ttaaagacct tttcatcttc aaagatatac cttacattta cttcaacttc
    67501 cgtttgaaca gcttcgtttt ttgttggagc ttcagatttt tgctcctgtg cataaacaac
    67561 cgtccaaaga cctaaaatac aactaatact tacaattacc gcaagtgcta ccgtccaaaa
    67621 cttattattc tttttcaaac tggttttcat ttgttttctc ctttttcatt tctgcttttt
    67681 gtctgtttac ctttgctatc aaatcgctga ttgtgatgtt gttctttctg caaatggcaa
    67741 tgatttcttc attttcaagc tcttcttcac gaatgaataa aggctccaat tcttcatcaa
    67801 tcagagcctt tttatccttt aacttcttta ttctgttttt tactgttgta agttcctttt
    67861 tcaaattgtt acctcctatt tctttacatt tggcggaaaa ccgaatccta cgggatggtg
    67921 cttacaaaat gttgctatcc aatcatctaa ggtagttact cttattcgac cgatgttatc
    67981 aatcactttt ccatctccaa tgtaaatacc tacatgacca taggtaagcc ctgcactgct
    68041 tccgctactg ctgctttcaa ctgccacaag cattcccact tttagctttg acctgtctga
    68101 tgtaaaggta tagtttcggt acatatcaca ggcattcccg cctatatatc caagtcctgc
    68161 attttgatag acctgtgata cccacatggc acaccagcct gcacccggag atggcgtaat
    68221 gtatgcagca ttaacaatct tcttttgtac ttccgtagat gcctcatact cttttccacc
    68281 gccgatacct ccatttgcac tgataaggtc agaattacca aaggcttctc tcatattgcc
    68341 ttgtgcaagg aacaaggctt catagtgctt tagattatcg ggatagtttg caaagacctt
    68401 tcggataata ctgtccatct cttttttatg aagcgttacg atgagttttt tatactcata
    68461 aggttcttcg tggctttcgg tatattcatt gccatcttca tcggtatagg tttccgtaac
    68521 cgtcctgtat ctgatttcaa tttcttccct atactcaagg tcatacatgg actcaaataa
    68581 ttcttttaat atggattcta cttccgatac actctttacc tctccgcacc ttgatgtaat
    68641 gtaggataaa agctcatgga cattatgacc gatgtattct gtattattta agatatattc
    68701 atcatatcca ggataatttt ctttcacata gtcaacttca ctttgaagct caccctccat
    68761 atctgaaaat ttctgattga tttcacttag gacatttggc tttgataaat agcttgttgt
    68821 aagcacagag cttgtagagt tcataaagcc tgtcattccc gttcctgcaa agttaatcac
    68881 aaaagtccct aagataatga tacctatgaa aataagcatt agtccttttg cttttcggat
    68941 aatcatatcc tttgagcttt tcagtgttcc gataagtccc tctttaattc gatctctaag
    69001 ccttgactta ttctcacgag aaattgctgc ctttacctga tttttctttt gaaatctttt
    69061 atatgcactt gctcttttat actcatccgt ctttttcagt tcctttttgg catcacgaaa
    69121 ttccaacttt gacttacgct ttctgatttt atagtcctta tttgtaaggt catagcctct
    69181 tttagctctt ttcttatcag agtacttctt tatgccatga atgagcttgg agcttgtatc
    69241 tgctgtcttt tctcctgctt ccactccttg attttcatca cttccatgag acaagtaatc
    69301 tcttacagtt tcacttcctt tagcaagtcc tgaaagggca gataccttta ccatgtcttt
    69361 ttttagcttt ttcttttggt cttttgatag gctgctataa acttttccgc tgacagcatc
    69421 ttttcccgcc tttttatcat cagccttatt tccctttggt gcatcgtcct ttttccttgt
    69481 ataaaggctt tcagaatagt tcttcctctt gtacctgctt ttttgagtct tatgattttt
    69541 aaaggaattt tctaatgatt tttctttatg ggaaagatta tcctccacat cataggtcga
    69601 ttcaaaatag ttgctgtctc taaagtcatt atcgtatctg tctataatcc cgtcattatc
    69661 aaggtctttt cctaaaggat catagatttt tccatcctta acctccgtaa tataatctga
    69721 tcttcccgtt tcaattgcgg aatttacgtc tcccttatct gaagttctat atttttcgtt
    69781 tctcttggat gttccataag acttttcatt atcagcactt accttacttg ttttttcatg
    69841 cactttatcc tgaaaccgtt ctttctcatg aacgatttta cctctgtaat catcgttatg
    69901 ttttagctta ctttcttcag gtatcgtatc tgttttacta tgaaacatct ctctttcaag
    69961 gcttgcctta tgcctttcct taaaatcctt tttcagcttc tttcccatag gctacctcac
    70021 ttcttccggc ttggtagtca tcttctgata taaaattgta tctttcggaa acttatcaat
    70081 gaaaggcaca atggtatttc caaagaataa gagtccctca ccttcatttg aattagtaac
    70141 atatctgagc tgtggaagtg agattttaag ttttcttgca agtatctccc tatctcctga
    70201 tgcttgatta agcattaaga caaagtctgt attgtcaaag atattttcta tctccttact
    70261 cataagtagg tctttgacat tctgcgtaat acctgttgga atacctcccc atttacgaaa
    70321 tcttttccaa atctctacgg aataggatgc tgtctgctca tcttttaaaa gcaaatggaa
    70381 ctcgtcgata tagtaccttg tagccttgtt tcctctgttt tgtgacacct tattccacac
    70441 ctgatcctga ataacaagca taccgatttt ctttaattga cttccaagct ccttaatatc
    70501 aaaacaaagg agcttcttat ttaaatccac atttgacctg tgattaaaga cattgagaga
    70561 ccccgataca tagatttcca tctctgttgc cagcttctta ccgacctttt cttcctgccc
    70621 ttttaacata tcgtataggt cttgaagtat cggcatattg tcaggagtag gatgttcaaa
    70681 atacttttca tagattttag gaaggcacct atctataacg gacttttctt ctgctgtaag
    70741 accactaccg cctactacaa gctcaagcat actcatgata aagtttgcct tgtctttcag
    70801 cggtgcatcc ccatcaccgt agttcatgtt tatatcaaga ggattcaggt aatccttcga
    70861 cttactgctg accttaatga cttctccctt aaactgcctt acgaggtttc catactctcc
    70921 ttccggatcg cagataatca catcatcatc tgttactaaa atcgcatttg ccatttctct
    70981 tttggcacta aaggacttac cgctgcccgg agttccgagg attagaccgt ttgggttctt
    71041 taatttcttt ctatctgcca taatcaggtt atggcttagg gcatttagtc cgtagtaaag
    71101 actattactt gaattgataa aaagctcctc tgtggtaaat ggcataaata ctgccgttga
    71161 tgagcttgtc aatcctctat ctatttcaat cttatttaca ccaagaggca gcacgctcac
    71221 taaaccttgt tcctgagaat ggtcaagtct tttcagctta cagttatgct tatttgcaat
    71281 ggagcttatt tgagcaattg tgttatcgag cttttgcact gtccttgcaa agttcataaa
    71341 gacgatactt accacaaaca ttcgctcatc tcttgtctgc aagtctttta agaggctctt
    71401 tacatcctca ccataggtaa ttaagtccga tggaagaatg tccatatcat aaccgcttct
    71461 taccgccttc ttattttcct caattttcat cttatcaata tcagtgtttt ttcgttttac
    71521 catcttaatg gcttccgatt ggtcgattgc cctaatatga aaggaaatat tgatgttatc
    71581 gtcaatatcc aaaaactcgg ataacatcct atctgaaagc tcactggcaa ggatttgaaa
    71641 atgacttgtt gctccgatga atttgccgaa cttaaagtat ctactcggtg taaagttaaa
    71701 ctcatcaggc acaatatatg tctttgtgct ttcccttttc tttaggtctt tgtaggaaaa
    71761 tttaaatgtt ttatttggat ttaaaacatc atgaagtatc tttagccttt cttctccgtt
    71821 taggctttct gctcttactc ccatactttt aagactcgat aatatatcta tctccagtct
    71881 ttcaagtttt gatgttgcct gttctaaatt atccgcttcc actgtaaagg ttacatactt
    71941 tgattttttc aatccgttat ttccctttac aatctggctt ttaagcatct ctctaaattc
    72001 aaagcgtata tcgtcgaaac cgtccttttt atccggtatc tgaattgccg acttcatttc
    72061 ttcgtttcgt ccgagctgat tgatatatga aaactcaatg ctgatacttg gatcaaaaga
    72121 gtttaggaag tttgcaaatt gattaaaaat caagtcccta tcttcatcta aggcaagctg
    72181 atagttaatg tcctgaaagg ctatactttt actgaagtgc ttttcatcaa gctggcatat
    72241 tccgcttttt aaaagcctta gatagggaat ggtatcttct accgtatatc ttttcggttc
    72301 tttcttaaag ataaggtcaa ggattcctcc cttatctttt tttgacttgc aattactttt
    72361 ctttaagtcc cgcttttgac ttctcaatgc cttttcgttt tgcatgagtt ttatttgctg
    72421 aatttttctt ttcttgttca aggtaaacct cctttctcac tctcttttgc ggttgataaa
    72481 acttatgaag ataaatgtac ttaaagtatt tctcaaatgt cagtccgtct ttttcaaata
    72541 gtgtgatgaa aaagatagga agcgtggata cgataaggaa tatgacagct atgtcatttg
    72601 gcacaaactt cctcataaat aaatagactg gtattccaac cagtcctgca agtgtgaagc
    72661 ctatgagctg ccttttcgtt aggttaaaag caacctttgt ctttacccta tttaagtctt
    72721 tagggattgg tacatatgcc atatcttacc tcccatcttc tttacccttt gacagctcct
    72781 caaagtgttc atatacagag ccgatttctt cctgaatagt cgcaagctgt tcgtctgtgt
    72841 tcttgttata tctttgctgt attaggtaaa aatcgttatg gcagcgacca atgtcctctg
    72901 ttttttcttc caattcttcc accttattat gaagcctgat cctatcaatt atcgccataa
    72961 tacctgctcc aattactact ataaatactg tttttctttt gttcatatta cccttccttt
    73021 cttttagtgt gcatttaata cgcttttggc cagtgttccg ctctttaaca tcattaaccc
    73081 tagcaaaacc gcatatccaa gtatcgtaaa ggtacttgtg tgtatatctg ttatctgtat
    73141 tgtcttaact aatactgcgt atattccaag acaaaccatt aaaaagagtc cttgtaaacc
    73201 tatggcaaac aatcctttga tatagtttgt tccaatctgt ccccactctt tgtttcccat
    73261 tgtggcaaat ggaatggctg aaatggatga gtaaacataa atctcaaaca ttcttccgta
    73321 aaccacaagc ataatcacaa ttgaaatgac ctgtattgcc acctttataa gcgaggtttc
    73381 aaagagtatc atgacaagct ctccaagacc tttatccttt aatccatcta ccatttttac
    73441 tatctgatct ccggagataa cggcagaagt attgattacc cctgccgctt tatttaccat
    73501 gtgctgtgcc acatcaaaga ccgccattga aaactcaaat gcatgtgata ctaaccatac
    73561 agcaatccac atcttgatga tgtacttgaa aaattcaaaa gtatctgtat cgtgcatatt
    73621 gttcttttgc attaccatat tgataagctc gatacaaagg actgctgtga tgattagccc
    73681 tgctatggga ataatgacgg aatcgttaat gcttttaata aaggcaaata catctccgtt
    73741 ccaccccata ggagtttttc ctacatctgt tgcaactgca ccaactttat cgttgatgtc
    73801 aagaaacatg gactctaagt ttgcttgaat accgcccagt agaagctctt taaagaattc
    73861 ttctatcttg tcgaatattc caaacatcta agctctcctt ttcttattac ttgagtacat
    73921 ttgcaagaag cggaatcagc ttaagtccga taaggacaat gcctcctccc gccataagct
    73981 gcttgatgcc ctgagatttc gctcccggat tatcattacc atatccttcc ataaggttaa
    74041 taactcccca tgctccaagt ccagcaccta ctgccataac taaaatcttt aatacattta
    74101 ctgcctgtgc gaaaaattcc ataatttatt cctcctcatt ttcttctttc ttctcaatct
    74161 tgttatatga cttcactaca aagtttttgt aagtctttcc ctctttttca cgcttcttaa
    74221 agtagccgaa tacatgaatc aaatcgcctt tttcaaagtc ctctgctttc tctgcttttt
    74281 ctccgtaggc tgcacaattg atgtactcct tgccctttcc atattttttt acaagcgtaa
    74341 agtttacaac ttctacttct tcaccctctt tttcaaaact tgagaaagta ggttctgcca
    74401 ctaagttggc gttgatgtta atcatttctt gtttcatctt tttaaatttc tccttttcat
    74461 ttcaataaaa aaaacgactg gagtttttct tttccaatcg ctgatactct tactatttag
    74521 ttttcgttta agtgggattt ctgatcctta tcatcttgcc tcctgatttt gaataaaaaa
    74581 acagcaaatc tttttaagac ttactgcatt cttgtaataa ccgtctctct atttaatttt
    74641 gcttttcctt ttcgcttcat atagctttct atgtcaaaca aattcttctt gtcataatcc
    74701 tcaagcagct tataattctt gtgctttgta atatcgtatt tatctgaaag aaaaggtctg
    74761 acacctctaa gctgaaatat acattttcca ccgtccatta cagtaatctc atcttgactc
    74821 atcagttctt tgccacaatg tcaagtgatg aattaaaaaa agctatcaaa gaaatccttc
    74881 ttcgatagca gcgtattcaa catctattca catttcctgc cttgcgttct tcgagctgat
    74941 gaaatataat aagaaatgtt gtcggaggtg cgaatatgga ctacatgacg ctcaaagagg
    75001 caagcgaaaa atggggcgtt tcgtcccgac agataaatta ttactgcacc gatggacgca
    75061 tccccggtgc tgtcaaaatg gccggtgtct ggctgatccc caaggaggca gagaagccaa
    75121 aggacagacg gtataacgaa agcaggtgat acagtgctgc atatagcaat ttgtgatgat
    75181 gaaaaagact ttgttcagta tttgaccgat ttactgaacc aatacagcaa ggaaacagga
    75241 cgggacataa agattacccc gtactatgac ggtatggagc tgattgaaaa atacgatcca
    75301 accatagacc tgattttcct tgatattcaa atgaaggtgg tggacggact tcatgctgcc
    75361 gagcgtatcc ggcaaatgga cgaaaccgtg ggcattattt ttctcactac tcttacacag
    75421 tatgggcttg agggatataa ataccatgcg acgaactaca tcattaagcc catgaaatat
    75481 gcccggctca aatcagaaat ggacaaattc ttggagcgca gccagaaaga agataccccc
    75541 tctctggtga ttaccaacga taccggcaaa tataaggtgc cgctaaaatc aattcgatat
    75601 gttgaaacat ataaccgcaa tctgatgttc cataccgagc aggaaaatat tatctgctat
    75661 aagagcatga aagaagtgga acgggagctt tgcgacaaag actttgtgcg ctgccatacc
    75721 agctacattg tcaatctgtt ctatgtgaaa ggcatcaaga agctggacat tgaattgatt
    75781 acaggcgaga tcattcccat cagccagccg aaacggaaag aatttatgga acggctgacg
    75841 gactattggg gggatatgct gtaatgtggt tatatcaagt gctcgacata acagcaacgc
    75901 tgacagaatc tttgggactg tatttattca gtatttgttt ttgcaaagaa ccacggtatc
    75961 gtgcttctgt aaatagatgg cttataacag gtataagttt tttgtgtgcg tatacattga
    76021 catggttttc tgaacttggc gcactcaaag cgccttttct tcttacgatt tatcttgtcc
    76081 ttttgaaagt ttgttataga gattctgtct atcaatgtgc tgttgctgaa gaactgaatt
    76141 atattgcaac ttgttctcga tattcgcaag gtagcgcggg gaaatatata actcgtcgct
    76201 tacctttttg cggctctcgc cgtattcatt tctcgcggct tttatagctg ccccgaaagc
    76261 cttaaagtcg tacaatggta cgggtctttt tgccattttc attcaccctg ttacatttta
    76321 cagttcacct ttctttttgg atatgtccac acaattcata tcattaggtt aaatacttcc
    76381 tgttgtgtat tgacagtaga ctgattttct gataaaataa aatttatgta aaaggaggcg
    76441 gcgtttatgt tgcatagcat gcgtattaga taagcattga aaaaaaggat tttcccattt
    76501 tcaacatggg cttttttgtc atgcttattt tgcggatgct atacaaaaaa ctaacgacgt
    76561 atagatatag tatagacata gtgcaagcta tgccttagtt ttgttgtact gctctgtgca
    76621 ttttttgggt agggaaacca ccggctgtgc cggtggaggt accccgtaaa aaagctttag
    76681 cttcaagcat cgagcgaagc gagctgctaa cagcaaatta tcagtgaaga aagacttgca
    76741 ttagaacagc ggctgcccgt ttacgggctg cggggcaaat gatgcgggtg aaataaaatt
    76801 cagtgcgtct tgagacgcat gccggtaata ggcccttata gggccaactc aagccaccgg
    76861 cttagccggt ggttatgact tgtgtaaaaa ggacgagtga aatataatgc ttaaaaaata
    76921 ttggataaaa tgtccgattt gtaacggaaa gacgagagtt caagtatttc ataatactgt
    76981 attaaaagat tttcctcttt tctgccctaa atgcaaattg acgcatatca ttgatgtaga
    77041 aaaattagag attgtaatca aaaatacaga aaaacaaact tttattattt agaagaaagg
    77101 atataaaaat gaaacgttta cctaaatata cgcctgcgga agtacggaat gatccatacg
    77161 gatttactta caaagaaatg tcggaagtta ttggcgagaa tgaagcaaaa gccttatatg
    77221 aagaattata taagcaatta ccacgcaaaa aaaatctatc aatgttggta aaaaatattt
    77281 gcaaaagcag tgatactgaa aagtatgttt acgaactgaa agacaacaaa tacattgaaa
    77341 cggtttttat caagcggcga gatggtggaa ctgtttgcgt gagcacacaa gtcggttgtc
    77401 ctgttggttg tattttttgt gagtccgggc gaaatggctt tgttcgtaat ctaacatcgt
    77461 cagaaatcgt acaacagatt atattgttgc gtcgaaaagt aaaccgtatc gtttttatgg
    77521 gtatgggaga gcctttattc aattatgaca acttgataaa agcaatccat attctccgag
    77581 atagatatgg gctcaacttt ccaaccgacg gcattaccat atcaacagtt ggtccggtcg
    77641 atcaattaaa aaaattgcgc gaggaacatc ttaaaattca gttgacaata tctttacacg
    77701 cagcaacaca atctgcaaga aatcgtatta ttcctcacat gcgcatatat gctattgaag
    77761 atgttgttaa gcaagcctta tcctattctg aaaggcataa tcgcaaaatt gtctttgcgt
    77821 atttgctttt accgggtata aatgaccggc cctcagatgt aagacaactt gcaaaatggt
    77881 ttcggggcaa aaaagttatg attaacgtgt tacaatacaa cccaacaagc aattcaagaa
    77941 ttaaagcacc acagaaacgg gaaatagttg cattcaaaca tcaattagag caagcaggac
    78001 ttgaagttac tatgagagtt tctcatggca gagagattaa cgcggcttgt ggacagttag
    78061 ctaacacata taataaattc aaaaaaaaat gattaaaagt gccagacgca tagacgcaga
    78121 gccgataacg cattaggtca aaaaacctat gtgttatcgg cttttttatt taatattgcg
    78181 caaaagccgc tgttccctat tatagaatgg attgcgggta gtgtattaaa gtcgcccttt
    78241 tttaaggata cggcggtatc ggggaggtat cgccgtgtcc atttttattt actgtaaccc
    78301 gcctaatgct ttgcggtcaa aaaaagctat gctccgcaag cgggatattc cggctatgaa
    78361 tgtgaactgt caatacattt agctactgct tacatttcct ttgcgcccgt ccgcgtcttg
    78421 cggacgggcg cattttgctt ttttcaactt ttttctgaaa agcgcactca agagccatct
    78481 cccgaacggg tacggagcga aaggggcaga gaggacaagc ccttaactcc cgtcctctac
    78541 tccacgcggg aaggaggtga actctatgga gctatcttct tccgacaagg aaagaataca
    78601 acatcagtac gacgcattag caaagaaaac tttggtcggc gaagcgaaaa gccaccgccg
    78661 cactcttgcg aaacgcgcag cacgcgaagt tactttttcg gatttgagcg aaagcgaact
    78721 cgcgcagctt ttcacaacgg acgaatacga aagcgattat ttccgttttc aagtgtccgg
    78781 ctttgatgta ctcgtcaaaa atgaactgct tgccgaagcc cttaacgctt tgcccgaaag
    78841 gaaacgcgac attatccttt tgtcctactt cttggatatg agcgacgcgg aaattggcga
    78901 actgctgaat gttgtacgca cgacggtttt ccggcacagg aaatccgcgc ttgcgaaaat
    78961 caaacagtat ttggagggaa aagcagatga tgaataccgt taggaagtct gaaaatctgt
    79021 tgccgttccc tgtcatttcc gcagcggcaa acggcgacac aaccgccatg tgcgcgatct
    79081 tgaagcacta cgagggttac atagcgaaac tttgtacccg cacgctgaaa gacgacgcgg
    79141 gcaataccta ttcctatgtg gacgaggaaa tgcgtaacag gctgcaagtg cgccttatta
    79201 cccgcaccct tgcttttcat gtaggataat cttttagccc atgcggggag cgtgtcccct
    79261 ttccacgctt cccgttatgg gctatttgtc gttccgcaaa agcatatccg ctgttgatgt
    79321 gcttttgcag gccgacaaag cctattgttc tttgacaaag aaagcggcct ttggtgcgca
    79381 gcataacagg caaacgggta cattccgtct gtaccgagcc agtcggcggg tacgccatga
    79441 cagcttttcc ccatagggga aaagccgagc gagaactacc gcgccgtaaa acaggtttag
    79501 cagcttgtgg gcgacgacat acaaggcggc acaatgatac tcccgcgttg aacaccctca
    79561 aagtattgcg cggcgcaccc ataagcatgg gccggggtga aactcccgtg aggttgcagc
    79621 taacaaccgc ccgtttttgc cttttgacga atatagttta tccatacagg aaaaggaggt
    79681 ttttctaatg gataaaaaac agacaattac aaccgaacgc aaaataggga aaatcaccta
    79741 tcttgttcaa gcgttgccga gtgaaaaggc aaccgataca atccataaaa agattgagaa
    79801 actcattgta aaggatttgc agaaaaagcc cggaaatccg ggatttttag cgtccgagta
    79861 gtgcattagg cggcgggata tggtataatg atagcaacac attatacctg tttattcggc
    79921 tgtcggaaag gaggactaat gttacagtcg aataaaatca ccgcccttta ctgccgttta
    79981 agtcaagagg atatgcaagc cggagaaagc ggaagcatac agcaccaaaa aatgatactt
    80041 caacgctatg cggacgaaca ccattttttg aacacaaagt tttttgtgga cgacggattt
    80101 tccggcgtga gttttgagcg cgaggggctg caagcgatgt tgcaggaagt ggaagccgga
    80161 cgagtggcga cggtcattac caaagacctt tcccgtcttg gcagaaacta tctgaaaacg
    80221 ggcgaactca tagagattgt atttcccgaa aacggagtac gctatatcgc gatcaacgac
    80281 ggagttgaca cagcgcggga ggataacgag tttaccccct tgcggaactg gtttaacgag
    80341 ttttacgccc gcgacacaag caagaaaatc cgcgcagtta aacaggcaca ggcgcaaaaa
    80401 ggcgagcgcg tcaacgggga atatccatac ggctatatcc cagacccgaa caaccgccac
    80461 caccttatac ccgacccgga aaccgcgccg attgtcaaac aggttttcgc tatgtttgtt
    80521 agcggcgtgc gtatgtgcga aatccaaaaa tggcttgcgg aaaacaaagt cttgacgatt
    80581 ggagcgttgc gctatcagcg tacaggacag gcgcggtatc agcgggcaat gatcgccccc
    80641 tatacttggc cggacaaaac gctctatgac atattagcaa ggcaggaata tttagggcat
    80701 accataaccg cgaaaactca caaggtatcc tacaagtcga aaaagacccg gaagaacgaa
    80761 gaagaacaac gctatttctt cccaaacacc catgagccgc ttgttgacga ggaaaccttt
    80821 gaacttgcgc aaaagcggat tgctacccgc caccgcccga caaaagcagc ggagattgat
    80881 attttttccg gcttgctgtt ttgcgctggt tgcagacata agatgtatta ccaacagggc
    80941 gtaaatatcg agccgcgcaa gttttcctat tcttgcggcg catggcgcaa cagggcaagg
    81001 acaggcagcg agtgtacctc tcattatatc cgcaaaaacg tacttcttga tttagtgctg
    81061 gaagatatgc ggcgggtttt gcggtatgtt aaggaacacg aacaggactt tatctgtaaa
    81121 gctaccgagt acggcgacat ggaagcgaga aaggcattag cgcagcagca aaaggaactt
    81181 ttcaaagcac aggcgcgtat gaccgaactt gacacgcttt tccgcaagct gtatgaggac
    81241 aacgcattag gcagactgac agatgaacgg tttgtgtttc taacttccgg ctatgtggac
    81301 gaaaagaaat cccttgccgc aaggatagac gagttacaac agcagatcgc aaccgttacc
    81361 gagcgaaaaa gggatatatc aaggtttatt cagattgtcg ggaaatacag cgacatacag
    81421 gaattgacct atgaaaacgt ccatgagttt atcgaccgta ttttgataca tgaattagac
    81481 cgggaaacca acacccggaa aatcgaaatc cattatagct ttgtcggaca ggttgatacc
    81541 gagcaggagc cgacgcaagt tgtcaaccat gaccgccgca acatggtaga tgtaaaaagt
    81601 atcgctatct aaccccagca aaaaaggggc ctgaaatgaa agagtacacg ctaattatca
    81661 agggagaaat ggattttatc atcttatctc cgcaggtgct ttcttccctg attactcaaa
    81721 tccataacag cccggagcga aaagttgtgg taagtattga gagcatcatg ccaccaaagt
    81781 ttaccgacta tctgcttcgg gtaatcaata gcaaccgctt tagcaatgaa cggttccgct
    81841 atcgctacat tttagaaaat cctgttacaa agaaagggat gtatgagatt ttacggcaac
    81901 agctttcccg caccaatacg gagcgatttc cttgttttca gaccatacaa ttgaccgaca
    81961 ctttccaggg taatgtggag ctggacatgg agtgcaacga tctgttcttt tgggcttgca
    82021 aagatacagc agcaaagttt gtttacacgt tcccggatgg acgggaggaa acactggtga
    82081 ttgaatactg aatgagaaaa gccccatccc tcaatggttg agagatgggg caaactattt
    82141 acgctgcaat ctccgggatt tccccgacaa agttataaac aattctgact tcctgcacct
    82201 tctgaccgtc caccttctta acctcgccga tcaggatttt gctgataagc cggttcagta
    82261 cggactcgtc cagttccgca atggcggcat agcgccggat ttccttgata aaggttcgga
    82321 cttcgctttc ctgtgcgtcc gcccggctct gcatcaccgc cagatcgtgc aggcgtttct
    82381 gattggcttc ctgctcctgt tccagcgccg ccgtcagctt cataaaccgc tgctcggtga
    82441 ggacgccttt ggccttatcg gtgtacaggc tcaaaaacat cccgtcaatt tcctgattcc
    82501 ggtcttccag ccgtttccgt tccttctctg tctgggaagc gtccaccaga taccggcgct
    82561 ccatccggct gctgagccgc tggtagaacg catcggcgtc cttcatggcc tgcgccgcca
    82621 attcctgtat atccttcagc accagattgt acaaatccct tgcctcaatc ttgtggctgg
    82681 tacaggcgtt cttgcccagc cggttgtaag tctggcagat atagtatgcc ctgtcaatcg
    82741 gctcccgcat ttcgccggtg aagcggttct tcccggttct gccgaccttt tcataccgca
    82801 cctgcatgga cttcccgcag gtggcgcagt agacaagccc gtggaacagg ttatagaagg
    82861 ggcaggcgtt gcctttcata atggttggcc tgcggtcaat gatgtcctgt acctgttccc
    82921 attcctccgg cgtcacaatc gcttcgtggc agccctcgat gacctcccaa tcctcacggg
    82981 ggataatgtc ataagtgttg gagcggatgc ctttctggtg tgtccggcag acaagatgtg
    83041 cgcctttata aaagggattt ctcaggatat ggctgatcct tgcgctcccc catgaatagt
    83101 agttcacgtc acattctgta ttgcttttta ctctggtgat ggggatttta tcatccatga
    83161 gctgctttgc gatccgcata cagccccagc cgtccagtgc catatcatag atttttcgga
    83221 tcaccggcgc agtctccggg tcaaggatca gatgcccttt gtcctccggg tcacgcatca
    83281 ggccaagagg cggctgcccg ccgcagaact ttccctgccg ggaacgggtc atgcgtcccg
    83341 ccagcacctt tttggaaata tcccggctgt acatatcgtt caggatattc ttaaagggcg
    83401 tgatgtccat ttcctgacgg gtcaggctgt ccacaccgtc cgtgacggcg atatagcgta
    83461 cattgtgttt ggggaaaaag atttcgatat agctgccagc ttcgatataa ttcctaccga
    83521 gcctcgatag gtctttcgtg atgacgcagc cgattttccc cgcctcaatg tcagcgatca
    83581 tgcgctggaa cgaggggcgg ttgaaattgc gacccgtata gccgtcatcc acataatact
    83641 catactggaa catcccatgc ttttctgcga agtcccggag catgagtttc tggttgctga
    83701 tgctcatgct ctcattgtcg ccgccgtcat ccagagaaat acggcagtag agagcggtga
    83761 ttttttcata gacttgtttt ttcctgctca tagcgttctc cttctatgaa cagggacacg
    83821 ataccattat agtaccatgt ccccgtccct gaatcaaccg tttttacgca gctttttctg
    83881 ccatttcccg ctgatgacgc cattcctcga agtgttcgca ggtctggcgc tcaatgagct
    83941 gctcaaaggc ttcccgcatg gacttctccc cggagaactc ccgcaccacc acaaaacgga
    84001 ctttattctt ctgatttttg cttttttcca taggctacct ccatagagag acaggccgaa
    84061 cggcagcacc ggcaacgaag tccggcaacg aacctctaaa aacctgtaaa ctaccgtctg
    84121 gcctgcaaat cttactttgt gaattttctt gaaaaatctc gttgctttcg ttgccggaga
    84181 taatgataaa tattaaaata tcccttattt actggctttt tccgtatcca gacagggaaa
    84241 tccccggcaa cgaacccggc aaccaagtgg caaccatccc ggcaacagac cgccattttc
    84301 aggcgatcca ctccttcgga agctccaact ggcggcattc ttcctcgctc agttccacaa
    84361 atccatcttc gttgccgggc agttcgttgc cggaaacgtc ccgttcccag cccttctgcc
    84421 tgccgtatcc ggcgaacatc cggggattgg agaatggctt ccagcccgtc accactgtat
    84481 tcatgatctc gttgatattg tgaagctgcc accgcttcgg ctcgtcatag gtgtggccca
    84541 atgcctcctt aaaaagctgt ttggaacaga ccatgctgcc ggtataatgt tccagaaagc
    84601 cctgtatttg accggcctcc gtgtcctccg gcatgaaatc cttctgcacc tccacaagct
    84661 gccgctggat ggacttgctg aatttcatgg aatacttccc gctgcggtag atggtcatgg
    84721 cctccgccca gacctgcaac aggtaggctc tggaagcgtc ctcgtcctcc aaaatgtgaa
    84781 cctccgcttt ctccgggtaa atcatgatgg gaaggaaacg ccggttcccg gcccggtcaa
    84841 ggggcaggaa gtccagcgtg ttggatgaac cgccgaacac gcactgccgc agccggtctt
    84901 tgggctgggc ctcatagggt gtgcggtagg tttccttctg gcgactgatg aacgagcgga
    84961 tttcctctat gcttttggcg ctgctggtgg ccagcatctc tgacatctca atgatccagt
    85021 ggccttgcag cttcaaaaat acccggtcat cgtccagctt tttcaggtca tcggagaacc
    85081 actcgtcccg gatcgccagc aggcggaaga agctggactt gccagccccc tgtccgccca
    85141 ccagacagag catttcctcg tatttggagc cgggagaaaa cacccgccgg atggctccca
    85201 gcaggaagtg ttttaacatt tcctctacat aatcgctgac ttctgcacct aagaagtgat
    85261 ggagacagga gcggatgcgg ggcgtcccgt cccacacaag gccgttcagc acgtcctgta
    85321 tgggatggta gcagttctca ttcgccacga tggagagcgc cgccgtcatt ttcttctcgc
    85381 tggtcaggcc gtagttctgc tcaaaataga gaagcagata cttcacatcc gtatccgtca
    85441 gggcgctggt gttcctgcgc cagcccaaat cccgcacgat gtccacccgg tcagtcagga
    85501 ggttcagccg gatggcgtcc cgcaggagag ggtcatggga gaacaccgtc cggcagttgc
    85561 cgatggtgtt ggcgggctgg cccttctccg tgacagaaag gccttcccgc acctcgtcaa
    85621 cgctctgctc cggcgctaaa gcttcggctg cgctcatgac ggcctgccgg gtggctggcg
    85681 gtaaactctg atattcgctg ctcaatcttc ctcacctctt ttccatactc agcgaccacg
    85741 caggcccgtt cctccatact gccggacagc agaatatcca gcagatactc cgtgtacggc
    85801 tttttttgca gggcctccac aaacagcggg ttccatgctt cctccggcgt ctgcggggca
    85861 tattccttct cccagcgttc cagcagatgc agataatcgc acaacacccg gaaacatttc
    85921 tgttccgcct gccggtagcg cagttcctcg ctgatttttc gcttgcccgg cttcctgcgg
    85981 ggcgggtcat ggcctttagc gtcaaagccg accgagaaat cctccgccag cttcaaggcc
    86041 gcatctttct tgttcagccc gaacagacgg gcggtaaaat caatcacatc cccgtccgcc
    86101 tgacagccga agcagtggaa ccggcggtca accttcatgc tgggatgttt gtcatcatgg
    86161 aagggacagc aggtcatccc gttcctgccg agctgtatcc cataagattc cgcagcctgc
    86221 cttgtgggga cagcctgctt caccgcttca aacacattcg attttctcac ctccagacag
    86281 agaaaaaggc atccggtttt cacagaaaat cagatgcctt acaactctat atcgttcttt
    86341 ttggtcgggg cgattcgccc ctcacgttcc caacgctccc ggttatcccg gtcagcatta
    86401 atttttgcct ttgccagaat atccataatg gattctttgg ctttcttctt gacctgctcc
    86461 ttcccggctt gcttgacttc cggctgcatc agcgtccgct ggattttcgc cagagcgtgc
    86521 tgcatggcgt ttttgatttt ggtaatgacc ccatccagac gctcagcggc atactcacgt
    86581 tccttctttg gagctttgcg ctccggcgaa agcacccatt ttttcgattc ctccaccaga
    86641 cgaatatctt ccttgtgcgt ctcctgccgg acggtatcgg tcaccacctc caccgccttg
    86701 tcataggccg catcggaaac atcatctaac agtgtctcca cgtcctcaat tttgagcgtc
    86761 agttcttcca gcttctgctc ctgcgccgcc agttgctcct tctgtttcat caggatataa
    86821 tcctgttttt ccagatagtc ccgcccgccg taggacggct cctgatccag atgtagccca
    86881 tgccgtctgg cgatgtcaaa cagaatcgtc cggcaaaccg catcaaaggt ctgcttgcgg
    86941 ttgttgttcc ggcctttggg cttctcaggg tttgggagag ggatgcccag ttcttccagc
    87001 gccttttcct gctggggaca cagttccccg tagcggttat cacagtcaaa gacgtgccgc
    87061 tcatggatgt ggggcgtccc ctcgtccaga tggagcgccc agtccaggat gtggatatgg
    87121 gaaccgaagc ggcgctcaaa ttcctcataa aactcattga cgatggaaaa aagcgtgtcc
    87181 ggcgggacgg attctcccat cgtgccgatc tggtagatgc tttcctccgg gcaggtcttg
    87241 ttgtttttca gcaagtcctc cacggtgcgg ttgcgctccg tgtgccgggt tttctcattc
    87301 cgggcgttct gggcctccac atggccgccg taatgctcgt tgtagtacat ccgctcgatt
    87361 tcctcaaagc tgaaatccgg ctgctccggg ttctcccgga actcgtgtgt cgtaaagccc
    87421 cggtagcagt cccagtagac attttgcctt gcccgttctg cgtcaatgtg ttcgctgttc
    87481 tccacatcga accggcggtc attgtggcgg ggattatagg tgccatgctt gccggagcgc
    87541 ccattgtgtc gtgtcagttt caaacagatt tcctccttcc tgcgaagatg ttctggggcc
    87601 ggggaagggg cggcgaagcc gcaaatcctg cgaattttgc gtcaggtaat acccagtacg
    87661 agttgacgca ggcatcaact ctccctgggc aaggcgtttc acccttgacc cgataatggc
    87721 tgccgccctt aacctgccaa tgggcgttgc cccttgaccc cagcagtgcg ctgccgcccc
    87781 tgcaccccgg cacaaagggc tggctgccct ctgtactccc gcaccggcga agctggattc
    87841 caccgcagaa gcggtgtttg ccagtttcac cggctccgta tccgcacatt tgcgcccata
    87901 agcggggaat ggatacggaa tacgcctgcg gggattgccg gtcaaaacag cgggtgcaga
    87961 cccggcattt tttccgtaaa cgccccggtt tcaggcgatt ttttcttccg cccctaccac
    88021 ctgaaagcca tgctcttttg cgtaggcgct ggcggcggct ttccgttcct cgctgtacgg
    88081 cggcaccagc cggatcgaca gccgggactt atccagcaca taggtcacgc tgccctccgg
    88141 cgtgctgcgc tccaaccggc acagcagcgg gtacttccgg ctgaaatcag ccagcctgcg
    88201 cttcaagctg gcgttgaagg tgtagacgct ggcaaggttt tccgcctcgt tccagttgat
    88261 aatggtttct ttctcatact tagacagctt cctcatacag atcctcctca taatcagtgt
    88321 aagatttcag cacacgcagg ctgcgcttga ggcggcggta ctcgtccatc tccatccgca
    88381 gatggtggta aaaatcctcg taccagtttt cgcccacctc cgtctccacc ttccgggcca
    88441 gccccagcat ccggcgtttg gcctccgggt caaccgtcag tgccgtcagc catttcagcc
    88501 gtgtcaccgt attgtggtgg ctgggacagc cgtaagcgta gagaatcttc ttttctttca
    88561 tactcagtgt cataatgatt tcctccgttt ctttgctgcg gagccatgcg ccccgcatga
    88621 ttgataaact tgtttctgtc tgccggtctg cctgcaagcc gctcctgccc ggaatttctc
    88681 ccggcgtatc ggcctctttg gtgcgctcga tttctgtcct ggcgtcactt ccccggaggc
    88741 catacccctt gcagccggtc attcgatttt caaggttctg tgcctgtctg caagaaccag
    88801 tttaccgaaa aaagaggccc tttcccgtat atccaaaacg tcggaaaaac gcttgaaatc
    88861 cgcatatttc cacgcttatg gaatcgtgct ataatgggtg taatcactga aaaacgataa
    88921 cgagagaggg ggctttggat gtacgcaaag ctgacaatcc cggagcggct caaagacctg
    88981 cgggtggtag ataagcacct gacgctggaa caactggcgg agcagaccgg cctgtctaaa
    89041 tccgcgctgg gaaaatacga aaccgatgac tacaaggaca tcagcccgtt tgcgattgca
    89101 acgctggcgg acttttacgg cgtgtccacc gactatctga tggggctgac ggaaaataaa
    89161 aatcacccaa acatagaact tcaatctctg catctgagtg atgatatggt ggaacttttg
    89221 agcagcggca aaatcaacaa ccggcttctc tgcgaactgg ctacccaccc gaatttccgg
    89281 cggctgatga tagatatgga aatctgcatc gaccagatcg ccaatatgcg ggtggagcag
    89341 atgaatctgg tgttggaggc cacccggcag accgtcatga acaagtatgc acccggagaa
    89401 gatgacctct atatgcggac gctggaactg gggcaggtgc aggaaagcga tttttacagc
    89461 cacgtcatgc acgatgatct ggacagcatc gtccgggaca tccgggaagc acaccgcaaa
    89521 gacaagacca ccgccgaccc gcagcccacg ctggatgatg tgaaggaaaa atttgagcag
    89581 gccatagggc agggcagcga tacagaaatg ctgatccacg agttctgcga taagttgcag
    89641 ataccctttg agaagatttc ctcggaggac ttctcggcgt tcctgcggat actgagcctg
    89701 tccaagcagc tcaaaagctc caacaatatg aggggaaagg ccagccccat tcctcccaac
    89761 cgcaaggcca gacgtaagcg gaagtaaaat ttccatatcc ggaagcggca aaaaagccat
    89821 ccgccgattg attggcaaat ggctttcgtg aagctgtatt ctgttgtagt ggttgtgccc
    89881 agtttgggaa cagtcactat tgaagatgct attctttgtc tttctgcgat acctgtgcat
    89941 gggcttcctg ctgaacaagc agccccgcag aaaagccata tttgaagtgg ctttcgtttt
    90001 cctcacactg ggcgattgcc acctgctccc gcagttcttc aaccagtgca tagtcctctt
    90061 tgctcagacg ctccgataaa gtgtccatca gggcggcgct ggctttgact gcctgcttga
    90121 acctcggtga atcagcgacc accgtttcac agggataaaa tctgccgtta tacatttctt
    90181 ccagaatcat gcacccacct ccctcagaca aaaatcatct cagacaggat gatttcctct
    90241 acccggctgc ggatgctgtt catgcccccg acccatgcaa gctggtcacg ggctttcagt
    90301 tcctcggtga cgccctccgc agcctgcatc tgcgagatga tacacgccag tcggtcatcg
    90361 gcctgctcgt tcagatcggc aagatacgtc cagagttttc ccgacagaag cagttcattg
    90421 tactggccgg gacggtgttc ttgcagaaac gccttgtgta tccgacccca ccgcccgatg
    90481 gggcggattt cctccgacaa ctttagatcg gggatatagt agtctcccac cagcgtatag
    90541 ctgatgccgt tgtgatggat tttctttggt aaatgctcca tgttcgacct cctgtattca
    90601 gttttttcag aatccagttg atcgtgtccc tgttcatgtg aaattcaagg caactgaact
    90661 cttcacgaac aagtatggca tatccttacc agtcttttga tagtttaaac caaagctctt
    90721 ttgatttgac cttgtttccg acgtgttata caggtcgata gtttcttttc ccagtgtttc
    90781 agacaattct tttagcgtag ttttctcctt gccaccaaga aacaaggtac tatcacagtt
    90841 acctacgatt gtatcagcgt tatccttgta gattgccttt agctgagatt gtgcttgaag
    90901 tatgatactt gctgaaatct ctcttgaacg gattgttgca attaacttct caaacttagg
    90961 aattaagccg atattagcga actcatcaag tagacacctc acatggacag gtaatcgtcc
    91021 gccatataca tcatcggctt tatcacataa aagattaaat aactgtgagt acataatgga
    91081 tactacaaag ttaaatgtat catcggtatc ggagataata acaaatagtg ctgtttttct
    91141 atctcccagt gtatcaagct caagttcatc gtcactcatc aagtccctaa gttcctgaat
    91201 atcaaaggga gcaagtcttg caccacaaga aataagaatc gatttggcag tttttcccgc
    91261 agccaatttg tactttttat attgcttcac tgcaaagtgt gtaggttctt tcttctccag
    91321 tgcttcaaag agcctatcta tcggattcat ataggtttca ttatcttctc tgacttctga
    91381 agcatcaatc atatcaagca gagttgcaaa gttcttttct tctcttggag cttcatagaa
    91441 gatatagcca ataagtgctg tatagtagag tttctcagct ttcacccaaa aatcttcacc
    91501 tgatttttct ccctctccct tggtgtttgc gataattgtc tgtactaatt tgagtatgtc
    91561 cttttcactt ctaagataag caaagggatt gtatttcata gactttttga agttaatggt
    91621 atttaggatt tttatctcat atccgttatc ttcaagcatc ttaccgcact caaggactat
    91681 agttccttta ggatcggtca cacaatatga cgagtgcatc tgcataaggt tcggttttac
    91741 ataaaatctc gtttttccac ttcctgatcc accgattaca agtacattct tatttcttgc
    91801 atactttgga tttgccggtc tgccattcat ggttaatcgt tctgtttgcg taagtaggat
    91861 attgttttga aacttttcat ccatatatgg ctctatatct tttttcgttc cccatcttgc
    91921 tgagccatac tctttcccct gtctaaactt tttagcattt ttccctttgg tatatacgat
    91981 aattttgatt aaaacagcta ctaccactcc cattaaaata tccgtaggat gaatgcttgg
    92041 aagaaagctc atggtgttaa gttccagtat accttgaaat attttgtcta ttacatcgcc
    92101 accagtatat gctcttacat gatgagaaaa gatattgcca acatagaaaa atgcaagata
    92161 gggaatgttc tgctttagaa actttgcctt atcttgcacc ttaaataagc ctttgatgtc
    92221 ttttagtatc ttatctatca taggctttgc tccttttgtt tatttttgat tttctctttt
    92281 gaaatagagt ttttagccat ctctttgaac ttctcaatat tcttgtgaat agattctttc
    92341 ctttctgctt tcttttctga ttttgaaaga gcgtgcttaa aagctttatc catcactttc
    92401 atatctttgg cttgaaagaa tacagagttt ttacctgtct ctttattttt catcactgaa
    92461 aatttaacac cgtatctatt caactctttt ttaagttctt taagctcagc ttcttccact
    92521 gggatttctt caagctgtcc ctttttaacc atatctttta gctttacttc atttccgttg
    92581 gcattgacca gtttttcaag tcctccgaat ttctccgctt ctttcatcaa tttttttaat
    92641 aagtttaata gaacttttcc agtaacttta ccagcattta tctccatatt taaggtcttt
    92701 cttgctattt cttcattgat cacatcaata tcctcctctc atatcatagc ttacaagagc
    92761 cgaataatag gcatctattc cacttggtgc attataagcg gcggtcagga caaaagctct
    92821 tatatttcta atcctatatt cattttctct taatactcct actaagtact ctaaatgtcc
    92881 tgaattaagt ttcctaaatc tttcctttac tacttgtaca gatatctttg tttggttgat
    92941 agtaatgaaa gattcatcat ctaataccat tacatctgcc agtatcttta atatttcatc
    93001 aaactcttca gccacactct tattcccaat actcatatgt tcataatatc ctgtttggtg
    93061 tcgcaattct tctaaacaat tttgatatat atttttatag cttatatcta tcctccctcc
    93121 cttcatattc tctgaaaata attgattctt ttctttgatg gaaggatgga tggaaatata
    93181 tgctgaatta tttgtagtat tatttgtagt attatttgtt gtattctctg gtaatggttg
    93241 gtgcaaatta tccttttgca ttagtgcatt ttgaacctgt gcattagtgc aatctgcatt
    93301 attgcattgg ctgattttgc ccttatccat tggtgcattt tgccctaatg cattgggcat
    93361 agaatttttt aatgcttctg tttgtatttt ttgttttttc aaatccatat ccatatataa
    93421 ttcttcaagt ttatcattat taattgtata ccattttgtt ttatctcttg gatccttatt
    93481 gtaatttcca actaaaagat aacctgcttt ttctaacttt gaaaaagttc tttttactgt
    93541 atcaaagctc atatagtcaa agtcattttc ttgccatgct cgaattgaat tatatgtcca
    93601 gtatttacca tcatgataat tctttcctga ttttttattt atttctatcc aataattaat
    93661 ctgctgtagt atgagtgctt cgtttaatcc tatttctcta gcaagagttt tattcgcaac
    93721 tataggttgt tcatcaaata aatacataac tcatcaaaca ctcctttctt tttttcaaac
    93781 aaaaagacga tagttatttc tatcgtctaa aatcatatat aaatatcatt ttctaaatag
    93841 agcgtattgc ttctttcact cccgttaaaa cggctataac agctgttcca accattggta
    93901 ttccgtatgg gcttaacaaa aatcctaata tcaatgcttc tatccctatg gtaacctctt
    93961 tttgtaaaaa agatgctatt gctccaaata tgcaaaacat catcaacagg taaagtattg
    94021 ctgttcctat gccaagtaaa aatgaaagaa atgcaatgag aatacttaac gctatactaa
    94081 ttggaaataa gataattttt aatatccatc tcatatatac tctccattta tactaaatca
    94141 ttttaaaatg tcttaaagcg tccattatag cttcttcttt ttcaggcgta cactgtggga
    94201 tagcctgatt gtctttttta gatttattat aatgctctct cagttcaatt ccacatttct
    94261 tcttaatctg tgcaatataa agtgtagaaa cctttagccc aaatttttct aatacatact
    94321 ccttaatttg agcatatgtt gctttgctct ctgcacttgt caaatcaagc tcatccagct
    94381 taatttcaac atctatatgc ttatcgacat caagtttgga caataacgct accgtctcca
    94441 catgtgtaga atgagggaac atatctacag gttgtgcctc aacacattta aatccgtgaa
    94501 catttagata gtctaaatcc cttgctaaag tagaaggatt acaagaaaca tagacaattc
    94561 tttccggatt cattgaaaca atagtctcta ataccttttc gtcacatccc tttctaggtg
    94621 ggtctacaac tactacattg gcagtcttac cctctctata catcttaggt acaatttcct
    94681 ctgcctttcc aacataaaat tcagcattat gtatattgtt taatttagca tttatcttag
    94741 catcttttat ggcatcatct ataatttcta ttccataaac ctttttagcc ttttgtgcca
    94801 aaaataaaga tattgtacct atcccacagt aaatatcaaa aacagtatca gtatcattta
    94861 aatttgcata ttcaagagcc ttatcataca atactttagt ttggacaggg tttacttgga
    94921 aaaatgataa tggtgaaatc tcaaacacta agtcacctat ataatcgttt atttttccat
    94981 ctccatatat aactatattt tctcttccta gaatagcatt cgtatctttt tgatttacat
    95041 ttacaaccaa agtcttaaat ccaggtatat tttccttaag cactgaagct aattctttaa
    95101 gatatggaag tttgtttcca tttgctacta atacaaccat tacttcttta gttgtaaaac
    95161 ctatttttgt tactaaatgc ctaatcaacc ccgtgtgagt cttttcatca tatatactta
    95221 ccttataggc ccttatatat gtttttatta ttttaacaat tttatcattt atctcatgtt
    95281 gtattacgca tttttctgtc gatattacat catgagtctt ctttttatag aagccaataa
    95341 ttggaatacc attattcttt tgtattggaa attgtgcttt atttctatat ctatatggat
    95401 tatccattcc tatagtgtca tgaacttcta catcctctaa cttacctatt ctcgaaagta
    95461 cttgtttaac ttcatttgtt ttcatttcaa gttgtttatt ataatctaaa tcttgtatct
    95521 gacaccctcc acaatcccta agattgtcac tacacactct tttcaccctg aatggagact
    95581 tttctattat ctcaacaata tctccctcag cataattttt ctttacttta ttaatcctaa
    95641 ctttaacttt atcatgtatt aatccgccct ctacaaaaac tgtaatacca ttgtactttc
    95701 ctactcctac tccgccttga ccaatgtcta ctatatctac aatatacatc tcgtttttcg
    95761 aaagcataaa tcaccctcca atcaatctat tatatttaaa tctttacaaa cttttttctt
    95821 taaatttata ttaaaatatt gctattaatt aaactatatt ttttactaag ctacaatatt
    95881 ttattttacc aaaaaaaaag gagcttataa agccccttag taaataaatt tattattttt
    95941 cttataaaac tctagttgaa cctctatata ccacgcctct tgatgcatcc acagttacaa
    96001 cttctccatc ttttactaga tttgttatat cagttgcaga cacaataact ggtatatcta
    96061 aatttatacc tacaatagct gtatgtgatg tcattccacc attctcagtt actacagctc
    96121 ctgctttttc tatataattg ttcatttcag catcagtagc agtagaaaca agtatgtcgc
    96181 cttcattaaa gtctacacaa gcatttccat tctttattat acgaacttta ccttctaccg
    96241 tttgagtacc tacacctata ccttgcacga tttcttcgct tattacatga acctttatta
    96301 aattagtagt tccacttact cctactggta ctccagcagt tataactact aattccccat
    96361 tatctatata atcagcttgt ctagctgcct caattgcctt ttctataact tcatctgtat
    96421 ttcctgcaac agaagactta actggatata ctccccatgt aagagctaat ttattcatag
    96481 tcttttcatt atttgtagta gctattattg gagattttgg tctaaattta gataccattc
    96541 tagcagtata tcctgaagaa gtagatgtta ttatagctga tgcatttaaa tctactgctg
    96601 ttgtacaagt tgcatggctt attgcatctg ttacagtaac attgttagta ccattttcct
    96661 ttagtaatct atcataatct aaagtctctt ctgttctttt tgctattgta gccatcattt
    96721 ttactgcctc tacaggatat tttccagcag cagtttctcc agataacatt atcgcatctg
    96781 ttccatcata tatagcattg gcaacgtctg taacttctgc tcttgttggt cttggatttc
    96841 ttatcataga atcaagcatt tgagtggcag taacaactgg ctttgctaat tcattacatt
    96901 tttttatcat cattttttga actattggca tctcttcagt tggtatctca acacctaagt
    96961 cacctctagc caccattata ccatcagaaa cttttaatat ttcatctagg ttctctacac
    97021 cttcttggtt ttctatttta gatattattt gtatatcagt tgcattattg ttctctaata
    97081 cttctcttat tgctagtaca tcagatgcct ttcttacaaa agaagcagct atataatcta
    97141 ttccttgact tattccaaac tctatatcac ttatatcttt aggagttatt gctggtaaat
    97201 ttatcttaac accaggtaca tttactcctt tatgattttt aactattcct gaattttcaa
    97261 caacacaaac tatatcttct ccatttattt cttttactct taagccaact aaaccatcat
    97321 ctattagtat agaatctcct gatttaacgt cttcagcaag acctttatag cttactgtac
    97381 acatttcttt agtccccata atatctttca tagttatagt gaacttttgc ccttcttcta
    97441 aaaatacctc tgggtcttca aagttacctg ttctaatttc tggaccttta gtatctaata
    97501 atatagcaac tggcttattt aatttttctc taactttctt tgccatatca attctttctt
    97561 tatgttcttc atgcgaaccg tgagaaaagt taaatctaca cacatttaga ccattttgca
    97621 taagttgagt taaaatttcc tcactttgtg atgctggacc tagtgtacaa acaatttttg
    97681 tcttctttac attatttaac atatttgctc ctcctgagat attattccac agatttattt
    97741 ttaatactaa aacttatata gataatattt ttgccatctc ataagcttct ttatcaaata
    97801 ctttcttttg agctaaagct tcacttattt ctaaatcaat tattttgttt tcttttattc
    97861 ctacaactct agctgatttt ccatctaata ataattctac tgctcttact ccaagtctac
    97921 ttgctagtat tctatcagat acagttgggc ttcctcctct ttggacatgc cccaatacag
    97981 tgactcttaa atctgctcct gactcttttt taagttcctt ttctaaatca ctagcacttc
    98041 cgactccttc tgctaaaacg attatactat gtctcttacc tcttttttga gtagtcttta
    98101 atcttagagc aacttcatct actgtaattt ctacttctgg tactattata gtttccgctc
    98161 ctcctgcaag acctgcatat aaagctaaat ctccacagtg tcttcccata acttctacta
    98221 tgttaactct ttcatgagat gatgatgtat ctcttatctt acctatagca tctataatag
    98281 tattcattgc agtatcaaat cctatagtat aatctgtata tgctaaatcg ttatctatag
    98341 ttcctggtat gcctatagct gggaatccta agtcactaag tttttgggct cctgcaaatg
    98401 aaccatctcc accaattaca actaagcaat caattttata ctttttaaga atttttactg
    98461 cttttaatct accttcttct gttttaaatt cttcacatct ggaagatttt aatatagttc
    98521 ctcccctgtg tataatatct ccaacagaag ataagttcat ttcagttaaa tcttcttcta
    98581 gtaatccctt atatcctcta ttgattccat atactttgca tccataatat attgctgatc
    98641 ttacaaccgc tctaatcgca gcattcattc ctggagcatc tcctccactt gttagtaatc
    98701 ctatagtttt cattttttac ctccttggat tttatgtcaa ttttttatta taatcattgt
    98761 tattgtattc taatggactt tttttgtccc tatatcactt tttaatccca tcaagactaa
    98821 aaaaattaaa tgtccttaaa tgtccatttt gtgatattat atcacaaaac ggacaatatt
    98881 tttcatatta ttataatata tttagatttt tatataaaaa atcaagcttt tacttttatg
    98941 ttatctttag gaagtaactc ttctaagtta tttataaatt catcacatat acaagtcaat
    99001 gccccggtca ttttatatgc tttacgttta ccatttatat tttcatccat agggtacaag
    99061 tatatactgt cattacctgg atattgtttg gctatttcta caatattatt agttgtatca
    99121 gtatcagaca tactatctat tttcaaatac aattttttac cactttctgg cttaatattt
    99181 tctacatttc tagttcttcc tgaattgtag tttctatctg caaagtcagt atcatcattt
    99241 atatctttta tctctctagc tataagtttt gcattttcgc cttcttttat acttaatgtt
    99301 ccttttacat atattatatt atcttcattc aaaatgacat tatacttttg taataattga
    99361 ggaaaaacta ttatttctat agcaccatac aaatcttcta attcaataaa tgccataatt
    99421 tcatttcgtt ttgttgtttt aatagtttta gttacaatca ttccacccat tataacatct
    99481 gtttcattca tttgtaggta tgactcttct tcctctttta atgaatttaa ttttccatta
    99541 tccatagatg ttttttcttg tagttctttt tcaaattgtg ataaaggatg tccacttaca
    99601 tacattccca agacttcttt ttcaaggtta agtctctctc tttcttcata ctcttgcctt
    99661 ttaggtaaac tgtatatttg ttgaaaatca ctatcttcct cactatctcc aaaagcatca
    99721 aataaagaaa tttgaccttg aacatttttc tttctatcca tagatacact ttctaataaa
    99781 ctttcataac cagccatcag actagctcta ttttcactta tattatcaaa agctccacat
    99841 tttattagac tttctattac tctcttattt gtatcttttt ggtctaatct tttgactaaa
    99901 tctactaaat ctacaaataa tccattagat tctctttcag cgattatatt gtttattata
    99961 tttacaccaa cattttttac agctgctaga ccaaatctta tattgtcgcc ttcaactgaa
   100021 aactttgaaa aacttttgtt tatatctgga ggtaatacat ctatttctag tgctttacat
   100081 tctcttatat actcaactac cttatcagta tttcccatta cactggttat caatgctgcc
   100141 ataaattcaa ctggataata tgtttttaga taagctgtct catatgctaa aaccccatat
   100201 gcagctgcat gtgatttatt aaatgcatat ctagcgaagt ctatcatatc atcaaatatt
   100261 ttattagcta tttcctcttc tacaccattt ctgatacacc ctgcaatttc tatattacca
   100321 tcttcatcaa atttaccatg aataaaatat tgtctttctt cttccatcac gtccatcttt
   100381 ttcttactca tggctcttct aactaggtca cttcgtccgt aactataacc acctaaatct
   100441 ctaacgacct gcataacctg ctcttgatat accaaacaac catatgtaac ttccattata
   100501 ggctttaatt tttcatgtag atatgttaca tcttttgggt tgcttttatt ttttatatat
   100561 gcaggtatag aatccattgg acctggtcta aatagggata ttcccgctac aatatcttca
   100621 aaattgtctg gttttagctg tttcataaaa cttctcatgc cagcactctc caattgaaac
   100681 acccctagtg tatttcctga tgaaagcatt tcatatactt tcgggtcgtc ataatccatc
   100741 tttgaaaagt ctattttttc tgtgtagttt tttataactc tatttttttc tattaaatca
   100801 agagtatctc ttataactgt aagagttctt agcccaagaa aatccatctt taaaagccca
   100861 agttcttcaa gtgttgtcat agtaaactgt gttgtgattg catcttgatg tttgtacaaa
   100921 ggtacatatt catctacggg attttttgat ataacaactc ctgctgcatg agtagaagca
   100981 tgtcttagca ttccctctat ctgttttgat atatttatta tttcttttgt ttccgggtct
   101041 tggtcataca attctttaag attaggattt gtatctaggg ccttatctat tgtcattcct
   101101 aaagcaaatg gtatttcctt ggctaccttg tcaactttat tgtagcctat atccaatacc
   101161 cttccaacat ctcttattgc agcttttgca cccattgttc caaaagttat tatctgggct
   101221 acatggtcat caccatattt tctctttaca taatctataa cttcttctct tctctcataa
   101281 caaaaatcta tatctatatc tggcatggat atacgttctg gatttaaaaa acgctcaaat
   101341 aatagagagt actttattgg gtctatatca gttatcttaa gtgtatatgc tactatcgaa
   101401 ccagccgcac tacctctacc tggtcctact ataatattat tttctttaga aaaatttata
   101461 aaatcccaaa caattaaaaa atactctaca taacccattt tttcaattac atctaattca
   101521 taatttaatc tctctagtat ctcattgcta ggattatcat atctctcttt taatccatta
   101581 aaacacaact cccttaaata agtttctggt gtatatcctt ctggaacatc atacttagga
   101641 agatgtatag tattaaaatc aaactccaca ttacacatat cagctatttt cacagtattg
   101701 tcaatagcct ctaatgcgta tggaaataat tcttccattt cttctcttga ttttaagtaa
   101761 aactcatcac taccaaatct cattctattt gggtcattta atgtttttcc catttgaata
   101821 cacataagaa catcatgtat tttcgaatct tctttattta catagtgaac atcattagta
   101881 gcaactagtg gtataccagt ctcttttgat aattttacta aaccagagtt tacttctttt
   101941 tgctcaggta aattgtgatc ttgaatctcc aaaaagaaat tttcttctcc aaatatgtct
   102001 ctgtagtcaa gagcaaattg ttttgctttt tcataatttc tattcattaa agcacgtgct
   102061 acatctcctg caaggcatgc agaaagtgct ataatccctt tgttatgttt tttaagttct
   102121 tccatgtcaa ctctaggctt atagtaaaaa ccttctacgt atgaagttga aactattttt
   102181 attaaatttt tatatccttc catattctta gctaacagaa ctaaatgtcc ttgatatttg
   102241 tcatagtttg ggtctttatc tctcaatcca cgtgcagctg tatagacttc gcaccctata
   102301 attggcttta ttccttcttt tatagctgtt ttgtagaaat ctataacacc aaacatacaa
   102361 ccatggtcag ttatagctat tgagctcatg tttagttcct tagccctttt tataagtttt
   102421 ttcaccctcg aaaacccatc aagtaaacta tactcagtat gtacatgaag atgagcaaaa
   102481 tctttgttca ttaaatcacc tcctgcttta taattttaat tttaccacaa atatatgtcc
   102541 taaaacaaaa acagagactt ttatctcaaa ataggaatta acttcaacat ataccattat
   102601 atgttataaa ttaatgctta ttctgagatt gtcccctcaa tttattgcta tgattttttt
   102661 ttcaaatctg ttgcaatttc ttctattttt ctaagtctat gattgactcc agattttcct
   102721 attggtggtt ctaacatctc tccaagttct ttgagagtca tatcctcata ctcgattcta
   102781 atcttagcta tctcttgtaa attttctggc aaactgctaa ttcctatagt ctcttgtatg
   102841 agcttaatat tttctacttg tcttactgct gcatttactg ttttagaaag gttagctgtc
   102901 tcacaattta ctatcctgtt tacattattt ctcatttctt ttactatttt agtattttga
   102961 agacttaaaa gagcgtggtg tcctcctata atactcaaca aatctgatat ttgttcactc
   103021 tctttgatat aaacaacgtg attatttttt ctagccacaa ttttactatt aaaacctaaa
   103081 gagtttataa gttcttttag agaatctgca aactcctcat tattagttac aaattccata
   103141 tgatagttct tttctgggtc gcttatagaa cctccaccaa gaaaagctcc tcttatgaaa
   103201 gctctcttac atccttcatg cttaattaag ttctctgaaa ttttgtttat agtaaaaaag
   103261 ccttctttat cttcaagtat acctaacttt tttaataaca tttctgaacc catttcgctt
   103321 gttaccatta atacataact gttatttctc tttagcattt gattcttatt tactgagatt
   103381 gtagtattga tattaaaatt cttttttaat aatttaaata ctttacgggc tattgaattt
   103441 aactctgttg ttatctttag atttagcttc ttatatccaa cgatttgtat acttccccct
   103501 gatttaacta gagctgataa ttcagctata ttacaacatt cattcccaga tataactctt
   103561 gctagttcat ttttggtttc agttgaaaaa gacatatcta tcacctatta actaattttt
   103621 ctttaacctt ttttttattt cttgtaaggc aacctttatt atctcctttt catcatcata
   103681 cctagctagg tctaccactc tatctagatg gataaattta gcatcaataa agccttcctc
   103741 tttttgtgga atagtatcca tattctttgc ttgcatcaaa taccaaaaaa ctgttttatg
   103801 aactgctcta ttttcatccc agttttcttt gaatgtatag tgtatttcac ctaaatattt
   103861 caatatatct gcttttactc cagtttcttc acttacttca cgtaatgctg cctcttggtt
   103921 attttcccct tcttctactt ttcccttggg taacacccaa tctccattga acttccttag
   103981 taaaagaatc gtattgccaa acaggactac accaccagca ctaacctctt ctctcatcga
   104041 tgttcactcc ttaaaactaa cataatgata aggatttcta cacaattttt taaaatcctt
   104101 ttttactaac ttttgttgta attatgattt agggctaact caataactat gttagatata
   104161 tactttgcat catgtcttat ataattattt tttatttcaa ttaaattctt ctctacggtt
   104221 tttataccca tctcttttaa tttatctttt tgctttttat ctaacaagac ttgctctgct
   104281 ccatcttgtt tatataagtc aagcatttct tctggcaata tctcattatt tgcgattaca
   104341 taatctatta aattctcatc agtgtgcttt actatagcat taacatgctc taatacattg
   104401 tacccttctg tctcacctgg ttgagtcatt atatttgcta tatatacttt tggagctaca
   104461 gacgatttaa tagcgtctac aatcccctct acaagtaaat tgggtattat actcgtatat
   104521 aagcttccag ggcccataat tataatgtca gcatcgtaaa tagatgcaat aacatccttt
   104581 aatggtttga catcttttgg atttaaaaaa attttatcaa tagagctttt ttgaattttt
   104641 gactcttcag gtatactaga ttctccattt attatattgc cattttctaa tttggcaact
   104701 aaatttacat cttccaaagt tactggtaaa actcttcctg ttatagcaaa aatttcactt
   104761 aatttatata cagctttttc aaagtttcca tacaacccat tcatagcagc caaaaacaaa
   104821 tttccaaaac tctgaccttt taaaagccct tctgtaaacc tatattgcat aacttcattc
   104881 attgttggct ctatatttgc aagtgctaat agacagtttc ttatgtctcc tggtgggagc
   104941 attcctaagt cttctctcaa tacacctgaa cctccaccat catcagcaac agttacaatt
   105001 gcagttatat tttgcgtagt gtgtttaaga cctcttaaaa atactgattg accagtacct
   105061 ccacctatca caaccacatt tggttctcta ttttcaacaa tagacctttg aaatagtttt
   105121 actttttcat tttttgcttt tttatatata aataacgata caattaatgc aatccaacct
   105181 aaaattccta caataataag taatttagcc atgtttgcct ccattatcgc aacatagagt
   105241 ctctatgttt ctttacaact ctatatccct tattagataa atcctccgct ataagatttg
   105301 ttatagtaac tgacctatgt cttccacctg tgcatccaac accaattact agatgttgtt
   105361 ttccttcatc tatatattga ggtactaaaa aatgaatcat atctaaaagt ttcacataaa
   105421 attcttcact gattttagaa ttcataacat aatctctaac ttctttatca tcaccagttt
   105481 tagctcttaa ctcttcaaca taatagggat ttggaagaaa tcttacatca aatactaaat
   105541 ctgcatcagc aagtatacca tgtttaaatc caaaagatac tacagaaata gttaggtttg
   105601 gattatcttc accagaagaa tatattttct ttatttcttc cttaaggtct ttaggtttca
   105661 tgttagttgt atcaattata catgtagata actcctttaa aggttccatt atctttcttt
   105721 ccatttttat accttctgga atctgcatat cttttgccaa tggatgattt cttcttgtca
   105781 ttttatatct ctttaacaat acatcatcat tacagtccaa atataccatt tcatattcat
   105841 aattttcttt ttctaaataa tttaagcttt catgaagcgc ttcaaaaaac tttctccctc
   105901 ttatatctat ccctagagca actttatcaa tacttgaatt tggttgataa cataattctg
   105961 caaatttagt tatcaaagca ggaggtagat tatctacaca ataaaatccc atatcctcta
   106021 aagctctcat tgtctcactt tttccagatc ctgaaagacc tgtaactata acaaatttca
   106081 ttgctaactc ctccctttta tcttatgttt attatattat aatgttttct actaacgata
   106141 tatccagatt agagtcagat atagtcttca tagctagttt aaaatcacca actctttctg
   106201 gacaatgtgc atctgagcct attataaatt tattttctag cccttttatt ttatttaatt
   106261 gatttacatt caaaaaagaa tggctactat ttatttcaag tctagtattt gtcttttttg
   106321 ctgtctttgc tacttcttct atatacacat cgcctttatc tcctggatga gtaattataa
   106381 aaatatcatt attacttatc gcatttatta cagcttttgt attgtattct tttgcttttt
   106441 cagttttaaa aatatagtta ttacaatgat ttaataagct tcttaatgat gttggagtag
   106501 aaccaaaatg atatccagcc ataatataat caaaatctct aataaattta tcatccatat
   106561 ctatattgcc tttatcatct aatatgttac actccatacc taaaagtata tttatatcat
   106621 tgtacttatc atttaaataa tctacttctt ctctcatttt gagaatatct tttttcttta
   106681 caccatatgc aatatgttta tagctatggt cagatattcc tattgttttt attcctttag
   106741 aaatggctac ctttacatta tcttcaatag tccctttgcc atgactatat aatgtatgtg
   106801 tatgataatc agccagtatt ttcatttgtt aatcctctcc aagtattttg acttcttctt
   106861 ccaacataac cccaaacttg gcatatacag cactttttat aacatatatt aaatccaaaa
   106921 tatctttagc acttgcttct ccttgattga ctacaaatcc acaatgcttc tcagatactt
   106981 gtgctcctct taaagtaaga cctctcaatc cagtttcttc tattaattta cctgcaaaat
   107041 atcctgttgg tctcttaaat gtacttcctg cactcgcaaa atttaatggc tgtttagtta
   107101 ttcttcttgt cgctaaatca tccattaaac tttttatttc atcataattt ccttcttgta
   107161 attctagttc tgctgataaa gctatatatc cgtttttcga tattatactt tttctatacc
   107221 caaattccat ctgttcattt gataattcaa atatattgcc ttccatatcc atcagtctta
   107281 ctgacttcac tatgtccttc atttcaccac catatgctcc agcattcatg gctagtgctc
   107341 ctcccaatgt accaggtatt cctgatgcaa actcaaaccc ttttaattct tgcttttgga
   107401 gagctttacc taaaactgat aataaagctc ctgactgagc agtcatccta gtatcattta
   107461 tctcataaga attgaaatta tcagctaatt ctattaccac tcctcttatt ccaccatctt
   107521 taattaaaat gtttgaacca tttccaatta ttaaatacgg aatagattct tcttttacca
   107581 acttaagtac attttttaat tgttcttcag ttctaggtct aactaatata tctgctggtc
   107641 ctcctaccct aaatgaaata tgttttttca taggttcatc gacttttata tcctctttac
   107701 ttaatatatt taataaattt atatatatat cttgattatt cattgtattt cctcccaaat
   107761 tatactgaac tttagctgtc attattattt aaattacatt agtatatagt attaactata
   107821 ttcaataata tatgattttg cttatcatat ggattttata ttttaagctt cttaattaca
   107881 aactatattc aataaatata taataaagta aaaaaaaaaa aataacaaca tataaaagaa
   107941 tataaataat ttaaaaaaag catcaatatc actgatatca atgctttaaa aggcaattta
   108001 attcgtatta tttatctaac tatttttgac atagcaaaga taataaatcc ctccaactac
   108061 tatggaacct ccaacgatat ttccaagcgt tacaaatacc aaattagtta taaattgaac
   108121 catagttata tttgctccta atgccattcc cattggtata aaaaacatgt ttgcaacact
   108181 atgttggaat ccgcataata caaataacat tattactgtc caacatgaag ccaattttga
   108241 cattatatct tgagatgctg tagccatcca tacagctaaa acgactaaaa tattacaaag
   108301 tattgctttt aaaaacattg atgctatagt tgaattaacc ttagcttctg ccacagctat
   108361 agcttttgta gctgcatctc ctgtcaatgt agaagaataa aacacaagtg caactagcag
   108421 aattgaacct actaaatttg caaaataaac cagtccccag tttcttaaca tttttcctaa
   108481 tgttattttt ttgtccataa gtgcaatagc cattaaggtg tttccagtga ataattctgc
   108541 tcctgccacc actacaagca taagacctac tggaaagacc atagcactta aaaagctagc
   108601 tacccctggg tctatcttgc caaaagtttg actaactatc atactcccca atgccccaaa
   108661 acctataaat gctcctccaa ataaacctaa tagaattgca ttttgtgtcg aaatgtttgc
   108721 ttttttaatg cctgcactta tagttgcttg tgcagtttcc ccaggtgtca agaatccttt
   108781 actcataaat ccttccccct taaaaattat actttccctt gtctttttat ggcaataatt
   108841 atataataac aatatgatat ataataaatt ttattaacat aaaaaatata ctatatactt
   108901 atatatactt gtctcatata attatactat ttattatata acaactttgt taatttcgaa
   108961 ataat
//
LOCUS       DAMJWO010000003       100761 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.004, whole genome shotgun sequence.
ACCESSION   DAMJWO010000003 DAMJWO010000000
VERSION     DAMJWO010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 100761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 100761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..100761
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.004"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(776..1285)
                     /locus_tag="PC366_000224"
     CDS             complement(776..1285)
                     /locus_tag="PC366_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HDF2575785.1"
                     /translation="MVMFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLSPI
                     YSNNTVIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRG
                     GKCEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLSEEFATILDISPNEVS
                     SYISSHIPQ"
     gene            complement(1496..2905)
                     /locus_tag="PC366_000225"
     CDS             complement(1496..2905)
                     /locus_tag="PC366_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575786.1"
                     /translation="MENYFDKQAKELYNKASEIINTHSMLKANRANEKFDMDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMSREIRFDISSPTGVNFKGAKYVIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDVEIDYSP
                     ERTHDIWDESNEIDKNTLREFTEKFINSSQKGKVPAYLESMISSLKNSKGELPWNLYL
                     NRIMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKAEIAVALDVSGSISDEEFKQAI
                     KEVLSIVKNYNHEITIIECDNEIRRVYKVRTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVKTNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            complement(2909..4039)
                     /locus_tag="PC366_000226"
     CDS             complement(2909..4039)
                     /locus_tag="PC366_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2575787.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LIVIDGNLLKEGEIGGLPTIESYVGVNSNGYKTEKKTTVYAVHNKLREIDEEISKSKT
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKEKNNSIPRAVFLNVVKGNVGKVIAEEFISFIESNSEPLISYEDV
                     FLRESIDEPIVERVKNESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIEFLKMY
                     PVDLMIGIMKDIRNSYIEVYKKAIENEGFVKSYFESYSLIRG"
     gene            complement(4051..4854)
                     /locus_tag="PC366_000227"
     CDS             complement(4051..4854)
                     /locus_tag="PC366_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575788.1"
                     /translation="MEKLRVIEMIKNNPNIIATIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEDMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYAKNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYNAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYILKKVSKDELESVLKEVLSKEDV
                     EEKYIRDFLNCSVIDRNSESIPIDKIMFIYKYGSKTAKKIAVDEKLKIM"
     gene            complement(5236..6117)
                     /locus_tag="PC366_000228"
     CDS             complement(5236..6117)
                     /locus_tag="PC366_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase-family hydrolase"
                     /protein_id="HDF2575789.1"
                     /translation="MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIEELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEVDQKALLDAV
                     NTGDYSNKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIKVLTEWLNAND"
     gene            6573..7547
                     /locus_tag="PC366_000229"
     CDS             6573..7547
                     /locus_tag="PC366_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575790.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKIYGFLLCTIFSYLCFNILGYNLTSFSIFIFIIIPLCFLLNIQDVIA
                     MCVVIASHYYLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIHEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYKLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGYTEFEAETGNLLLEELKRLM
                     LSMKNHPLPVDRTEFENRAILFLCLTELKQFLVNRKHAQMLRDNNFYK"
     gene            complement(7663..8694)
                     /locus_tag="PC366_000230"
     CDS             complement(7663..8694)
                     /locus_tag="PC366_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HDF2575791.1"
                     /translation="MKKIRKLATKLLITTIVLVSGMSMTVYGMTAKEVTAKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNNKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLSHPLPFDKTAYPTVGAVAQTQKPALPGKHTMLPHQDGAK
                     VVGKFGDIKDKHVMYEGVRCVVINSSVNTVTFLGSKSNLDPSNLTIAVIGFMNTPYGM
                     FALAPEGEPVEYPFKYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIEITDEKANIGL
                     GQIMYIRYE"
     gene            complement(9306..10157)
                     /locus_tag="PC366_000231"
     CDS             complement(9306..10157)
                     /locus_tag="PC366_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2575792.1"
                     /translation="MSCILKLKQIFEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDIAIAISYSGESKEVIKSIENAKLKGCKVICITKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNINNA"
     gene            complement(10174..11094)
                     /locus_tag="PC366_000232"
     CDS             complement(10174..11094)
                     /locus_tag="PC366_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA reductase"
                     /protein_id="HDF2575793.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDGIQGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLEHHFEQGTKIKVSYSGGVFKSGDLILEPLKKY
                     LNKTRFGIVRPVLTPDLGACLLAKKKYYSK"
     gene            complement(11204..12118)
                     /gene="murQ"
                     /locus_tag="PC366_000233"
     CDS             complement(11204..12118)
                     /gene="murQ"
                     /locus_tag="PC366_000233"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDF2575794.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAIEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVKYDVAEKFLEEADNRVKLAIFMIKS
                     GLDKDSAKSILDRQEGYISEALKSIEKL"
     gene            complement(12217..13314)
                     /locus_tag="PC366_000234"
     CDS             complement(12217..13314)
                     /locus_tag="PC366_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDF2575795.1"
                     /translation="MGRLGISIYPEKTTSKEIYDYIDKAAENGFTRIFSCLLSVKDTK
                     ENIIKKFKSINEYAKFKGFEVILDVNPRVFGELEISYKDLTFFKKTKADGIRLDMGFT
                     GSEKALMTFNPQNLKIEINMSNNTNYIDTIMDYQPNKENLTGCHNFYPHRYSGLNLEH
                     FIKCTERFNKYGLRTAVFVTSQNETTFGPWPVTDGLPTIEMHRNLPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DSLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFDFKPSTK"
     gene            complement(13547..14893)
                     /locus_tag="PC366_000235"
     CDS             complement(13547..14893)
                     /locus_tag="PC366_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2575796.1"
                     /translation="MLDKFTEFLDSKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYLKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPDLLKIVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEAY"
     gene            complement(14982..15290)
                     /locus_tag="PC366_000236"
     CDS             complement(14982..15290)
                     /locus_tag="PC366_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2575797.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGAKNGIDIDVLAVGTQEFENE
                     VKNGWDIAMVAPQVRHRFDYLKAFADEASVPCALIQAQAYSPLGGPKLLKQVQELLSK
                     "
     gene            complement(15551..15940)
                     /locus_tag="PC366_000237"
     CDS             complement(15551..15940)
                     /locus_tag="PC366_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575798.1"
                     /translation="MSNNKKKKRKKNNNYKNAKSNKNTKKEMEKNQRTDYNIPTISFK
                     SGLILIVSSLVSTVVFPLLLSIFGIDNRFGVVIGNSLITSFAVAYTRYFVETKRGFSL
                     GFFRLYILFVLSFAIIGYFWIYKGIHI"
     gene            complement(15942..17102)
                     /locus_tag="PC366_000238"
     CDS             complement(15942..17102)
                     /locus_tag="PC366_000238"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HDF2575799.1"
                     /translation="MITMYSVGLMSGTSLDGVDAVLAEISGNGRNTKVKQIEFITLEI
                     PKDIKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCHKANFHIANLDFIASHG
                     QTIFHIPRSYNNFVSSTLQIGEPAIIAYETNTKVISNFRVMDIAAGGEGAPLVPYSEF
                     LLYSDKNKNLALQNIGGIGNITIIPKSCNIDDVFAFDTGPGNMIIDGVCQRLFNRKYD
                     KNGYFASKGKINEEMLKDLMSHKYLSQAPPKSTGREVFGQVYLDNMLNKYKHVDKYDL
                     IATVTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGVHNLTLIGYIKELLLEVEVLTQD
                     EYGYSSDAKEALAFVILGNETLNNSFSNVISATGAKNKVILGNITPKPFGGK"
     gene            complement(17532..18551)
                     /locus_tag="PC366_000239"
     CDS             complement(17532..18551)
                     /locus_tag="PC366_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2575800.1"
                     /translation="MLVKYLKGRSKYIALPLVVVSIINIYLFAIDILKNRYSELIYLD
                     FLVLFIIMVFFVIDYINFRNSYINLYNCIENSGEIDSYLIDGQSFEENLIKDIIENLK
                     IKNNSDIETYKQSLKELDDYIAKWVHEIKIPISSLSIITDRLSSIEDSLDIKNQVAKI
                     NFLVNSILYSSRSNTMFEDVFINKFNLEKLVKMSIKNNSFLLIKNNVEVSLNELENDV
                     YTDSKCMSYVLDQIINNAIKYSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRV
                     FDKGFTGKNGRNQLYKSTGMGMYFVKKMIDSLGHEIEVCSKIGSYTIFNIYFYDISDY
                     LSLDS"
     gene            complement(18551..19225)
                     /locus_tag="PC366_000240"
     CDS             complement(18551..19225)
                     /locus_tag="PC366_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2575801.1"
                     /translation="MYRILLVEDDIDLSKEIALALEKWGFKVELIDDFEVVLDEFMDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIDILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GIGYII"
     gene            complement(19377..21284)
                     /locus_tag="PC366_000241"
     CDS             complement(19377..21284)
                     /locus_tag="PC366_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2575802.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NVLQEENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVVIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIVSLIVIGYGYY
                     LSTNIRTGDITSVLPVIGIIIVGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMKHIHKNAQEQRNVYTISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYGERLVSGNNVIELKSPQTIASIATKEVKTKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSQVMFNNIEKNLSLKNGYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AILKEVAIFYTLPMLSATISSYFALRLAGDLLMNDLSGIYILSLVICLIIFVIYGAVS
                     VNKFKSVVYKN"
     gene            complement(21285..22037)
                     /locus_tag="PC366_000242"
     CDS             complement(21285..22037)
                     /locus_tag="PC366_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2575803.1"
                     /translation="MKEILKIKNISKDYGIKGFKTNVLKNISLTVNEGDFIAIMGPSG
                     AGKTTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMK
                     LMDNIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLI
                     TNPAVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMIN
                     DGNIKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            complement(22355..23509)
                     /locus_tag="PC366_000243"
     CDS             complement(22355..23509)
                     /locus_tag="PC366_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2575804.1"
                     /translation="MINKAIKFKFIIFYFFSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDNINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTNKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSLLEKPTYLAGSYLLKKYSSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSINIGYNYTLMILSLFGCLAYGLIVLLNYLQE"
     gene            complement(23512..23979)
                     /locus_tag="PC366_000244"
     CDS             complement(23512..23979)
                     /locus_tag="PC366_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2575805.1"
                     /translation="MFFKRKKEASTINSYIDGKIINLGEIPDKVFSTKVMGDGFAMIA
                     KDNILKSPTKGVISFIAQTNHAIGIKLQNDVQILIHIGLDSATTKKENFKLEVKQGQE
                     VNMGEKLVEIDNKLLENTLYIPLVIVENPNTVKYHLSNLNQEGNSGIKVINFD"
     gene            complement(23993..24481)
                     /locus_tag="PC366_000245"
     CDS             complement(23993..24481)
                     /locus_tag="PC366_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575806.1"
                     /translation="MITNKIKNITAVLKDENIFLSVVMVCFLILPVLYIVYLELTSLF
                     TNISFSQLLNNDVNASLNLISNFSAVYSAYVIYNIKKNKEIKENMIAFYLVLLGQIFQ
                     IYTITIVIMFTYIYKFVGIKQIISSIKELQWGKSYKALFSSIAVCLISLFVMIIRIKL
                     IM"
     gene            complement(24495..25826)
                     /locus_tag="PC366_000246"
     CDS             complement(24495..25826)
                     /locus_tag="PC366_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF2575807.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVAKFPIESIKLYDNND
                     ERQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGIAYGLRTIGPIIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARILGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKLQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMIEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            complement(25840..27405)
                     /locus_tag="PC366_000247"
     CDS             complement(25840..27405)
                     /locus_tag="PC366_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003233606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2575808.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYIHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHIQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFGAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFVAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYVVQVVVGII
                     FSFIWFFLFTFLIKKFDMKTPGREEDNEETKLYTKNEYLETKDEKGNKLSKASQQASE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKVVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            complement(27574..28359)
                     /locus_tag="PC366_000248"
     CDS             complement(27574..28359)
                     /locus_tag="PC366_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2575809.1"
                     /translation="MRLEEMIFLNYNKLNDTDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            complement(28526..29725)
                     /locus_tag="PC366_000249"
     CDS             complement(28526..29725)
                     /locus_tag="PC366_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S41"
                     /protein_id="HDF2575810.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLANKDEYTKRIKNTENDEEFIEELSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKKVVDRYDSMNLKIKMPDDIFVKKELILKDVIKG
                     QIGYMYLPSMSSKNGSINNDLKIIGDYINTLEKHKALIIDIRGNLGGSDRYWQGIVSK
                     LIKNDVKINGYRIYRNNNEIVKKYTNARNIKLNPVENLPASVKENAPKEIIKDFNDFE
                     DTSYTIKSTDDSKFKGNIYLLVDRKIYSSSESFAMFCKETKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKNGICDEEFKTIPEFKVKDCKRTADFKDDNCIRKAL
                     ELENINY"
     gene            complement(30247..31584)
                     /gene="xylA"
                     /locus_tag="PC366_000250"
     CDS             complement(30247..31584)
                     /gene="xylA"
                     /locus_tag="PC366_000250"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HDF2575811.1"
                     /translation="MSEIFKGIGQIKFEGVKSDNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNVTDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKVNMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKMNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
     gene            complement(31680..33230)
                     /gene="xylB"
                     /locus_tag="PC366_000251"
     CDS             complement(31680..33230)
                     /gene="xylB"
                     /locus_tag="PC366_000251"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HDF2575812.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNIIKSCTYEYPLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSSNISSECIKGIGLSGQMHGLVMLDNEGKTLRNSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYINTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEITG
                     YVTRDVASLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLGEDVYEIIN
                     NQVSQVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDAIIKTSTKLEPISENVDTYKIYHRLYKRIYKSLKDDFKLLDE
                     VVNTKINN"
     gene            33438..34598
                     /locus_tag="PC366_000252"
     CDS             33438..34598
                     /locus_tag="PC366_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HDF2575813.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDIGYDYIFSSLSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHNSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKQLYYEDNQNAKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            complement(34754..35158)
                     /locus_tag="PC366_000253"
     CDS             complement(34754..35158)
                     /locus_tag="PC366_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2575814.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANDDSRIKIISGLNLGMVIESAF
                     LDTKELAAKLEKIGKDNISMVEQNASLLSDDE"
     gene            complement(35179..35661)
                     /locus_tag="PC366_000254"
     CDS             complement(35179..35661)
                     /locus_tag="PC366_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2575815.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKI
                     HNINVGNMSSRKDTTVLRPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            complement(35681..36490)
                     /locus_tag="PC366_000255"
     CDS             complement(35681..36490)
                     /locus_tag="PC366_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2575816.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIVVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            complement(36483..37262)
                     /locus_tag="PC366_000256"
     CDS             complement(36483..37262)
                     /locus_tag="PC366_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2575817.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQEQQYTVVGGMDEDE"
     gene            complement(37262..39340)
                     /locus_tag="PC366_000257"
     CDS             complement(37262..39340)
                     /locus_tag="PC366_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HDF2575818.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     NFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEVECPLEEIPIFLKQDSSYNFKE
                     LKNILGEVKS"
     gene            complement(40131..40652)
                     /locus_tag="PC366_000258"
     CDS             complement(40131..40652)
                     /locus_tag="PC366_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HDF2575819.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAINLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIPHVRQFNEYLKNDYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCNELMDKINDIQMVDGKGIFIEELEKLLKEYNLE
                     IPIVGFDELREDK"
     gene            40818..41384
                     /locus_tag="PC366_000259"
     CDS             40818..41384
                     /locus_tag="PC366_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2575820.1"
                     /translation="MDTKKVTFSSICIVINIVLGMVISMINIPLLFLDTVGTVLGAVV
                     LGPFWGALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISKKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTSSSY"
     gene            complement(41601..43664)
                     /locus_tag="PC366_000260"
     CDS             complement(41601..43664)
                     /locus_tag="PC366_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HDF2575821.1"
                     /translation="MKAGEIEFLSYLEGSNKSFVVPVYQRNYNWKKEQCKRLFDDLED
                     IIDSGFRTHFLGSVVSIYSMGKEYLIIDGQQRVTTVSILLIAMCQIIKEFGESKGIIT
                     TEEQIKECYLINKHSRDKDGKIKLKPIAEDRKAYYELFEEEMNTDRNSNIVSNYLYFY
                     NRIKEDNISIDDLFDAIQKLTIVEIELKNGEDDPQLIFESLNSTGLDLSEADRVRNFV
                     LMGRSSKLQEEFYNNYWYKIEKNTSSNVSSFIRDYLTIKERSIPNKNKVYFSFKRYVS
                     DNGIDIEILLKDLLKFSNYYREISYSCTDDNDVNKVLKRINKLEIFVSYPFILELFND
                     YNEGIINKKVLVESLNLVECFILRRIVCDVPPNALNKVFMNLGREIKKFSDYKENYSN
                     ILRYIFINKKSSQRFPTDSEFSNAFETKDIYNTKSKNKLYILERLENYNNKEIVDLEN
                     LINNNMLNIEHIMPQTLTNKWKESLGDNYKEIHDKYLHTIGNLTLTGYNSKLSNKTFE
                     EKKEMEDGFKDSRLYLNKYISSIDKWNEEEIKNRTKILLDRAVEIWKYPSVTYEPPSN
                     SENIFTLEDDDVNFTNESIVSFSILGESYKAKNWTEFYEQVALTLYDLDSVRFNSIVD
                     KTYKRDFIDNIKSRDVYKLRKGIKISENIYLETNLNTEAKLNIIRFLLNEFDIELNEV
                     IFSIK"
     gene            complement(44045..47380)
                     /locus_tag="PC366_000261"
     CDS             complement(44045..47380)
                     /locus_tag="PC366_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDF2575822.1"
                     /translation="MGNFDFLQKKKNFNSFNTACLEAEKSILVSPSTCATITRRALEL
                     AVKWLYANDSDLVLPYQDNLSTLIHNNSFIELIDYDMLPLLKYIVKLGNLSVHTSANI
                     ERGEAILSLNNLHQFVSWIDYCYSDEYTAEDFNEDLLLHGEEKRTRPDELKNLYERLS
                     SKDKKLEEVIKENEKLRKSLTEKRKVNTVNYDFKIDEVNEFETRKRYINIELKLAGWE
                     FGKDIGEEIEVQGMPNESGVGYVDYVLYGENGKPLAVVEAKRTSKDPKIGQQQAKLYA
                     DCLEKRYSQRPVIFLTNGFDMYIWDDYSDRKVYGFYKKSELQLMIDRRKSKKSLSSVT
                     INDEISNRYYQKEAIRAVCEALENKQRKTLLVCATGTGKTRIAISIVDVLSRHNWIKN
                     ILFLADRKALVKQAKKSFTKLLPNLALCNLLDSKDSPEDARMIFSTYPTMMNAIDDTK
                     SKDGKRLFTPGHFDLIIIDESHRSIYKKYKSIFDYFDSYLMGLTATPKDEIDKNTYSV
                     FDMENGVPTYAYEYNKAVEDGYLVDYTSIEFKTKIMEDGIKYDELSDEEKEEYENTFN
                     DDESIGDEIGNNAVNEWLFNSDTIDLVLNKLMTEGLKIEGEEKIGKTIIFAKNTKHAR
                     AIVERFNKLYPKYGGNFVKAVDYSINYVDSIIDDFSDKNKLPQIAVSVDMLDTGIDIP
                     EILNLVFFKKVRSKTKFWQMIGRGTRLCPDLLGVDMDKERFLIFDFCNNFEFFKFNPK
                     GFEGNKAETLTEKLFNIKVSMVKELQDIKYIEGKYAELRKELLEELITSVKALNEDSY
                     IVRMNLSYVHKYKNENVWSNIGAVAQNEIREYISPLITSYSDDELAKRFDVVMYNIQL
                     AYLQNNNASKGIRHVMVTAEKLSKLGTIPQIQQQKYTIEKAMTEDFWEDSDIFEVEEV
                     RISLRELIKYLEKSSQKIYYTSFEDMIVAEDRNDSVYNANNLKNYKKKVEYYLNSHKD
                     ELAIFKLRNNKKITKQDVETLEEILLKQLGNCDDYKKEFGDTPVSQLVRKLVGLDREA
                     ANEAFSEFLNNKSFNTKQIHFVKLIVDYVVKNGFIEDNKVLMEDPFRTVGSIIDLFEN
                     HIEERNKLIKTINKIKENASEIG"
     gene            complement(47430..47858)
                     /locus_tag="PC366_000262"
     CDS             complement(47430..47858)
                     /locus_tag="PC366_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575823.1"
                     /translation="MVIRNKLSWNSIEEVNRDFGSCLYDLQNFKILYDKEEMPELWAR
                     YIKEGFKSYMVSFLELTKAMLYYKSIDLNIKSKNFYDYLLACEYHNLLPKNSSIVIET
                     LRKLRNDDSHGYDIPQFEDMYELFTENEEVFVSIRNSCKK"
     gene            complement(47848..48228)
                     /locus_tag="PC366_000263"
     CDS             complement(47848..48228)
                     /locus_tag="PC366_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HDF2575824.1"
                     /translation="MRNIPNEIKNSIINVFPKENTLAIIIFGSYGTDKHTSESDIDIA
                     WIPIKKVPITELATKTEALRNILDIDVDLKIVTDNYTIALKKAILEGEVIYESKDFKD
                     YINKFYFENSDVIDILDWRDMYGN"
     gene            complement(48261..48569)
                     /locus_tag="PC366_000264"
     CDS             complement(48261..48569)
                     /locus_tag="PC366_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575825.1"
                     /translation="MNQIELDLYHDMVNIYKEADLQCNYKPTRFLQLINNKGALLAAK
                     ELINKEGATEGFTRLWECKRLDLSLEVLVLKEKYKELFTDEEREICINRLKDYGYKFN
                     "
     gene            complement(48602..49786)
                     /locus_tag="PC366_000265"
     CDS             complement(48602..49786)
                     /locus_tag="PC366_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HDF2575826.1"
                     /translation="MVDEAKILDVVSISRENVKKFDGERSYLSTGNLDFNKISNLEIV
                     TYENKPSRANQTVNIGEVIFAKMKDTKKTLVINKTNKNIIVSTGFYVLKPSKEILPQY
                     LYHYLNSSYFLNQKNRLSKGATQSALNNEGLANIKIRMYNLKVQEKVVRVLDKAQELI
                     DKRKEQIEVLDELVKSRFIEMFGTPSKNEKNWEISEIGKYLDVLTDYHSNGSYETLRD
                     NVTLLDTKGYALMVRTTDLENNNFEKGVKYIDEHAYNYLEKSKVFGGEVIINKIGSAG
                     KVYLMPFLNKPVSLAMNQFMLRFNEDKVNHIFLYNLLLTSYMESKIKEKVRGAVTKTI
                     TKDAVRKINIIVPPIRLQNQFANFVKQVNSLKFEMETSLKELEDNFNSLMQKAFKGEL
                     FN"
     gene            complement(49790..51253)
                     /locus_tag="PC366_000266"
     CDS             complement(49790..51253)
                     /locus_tag="PC366_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HDF2575827.1"
                     /translation="MITGELRSKVDKIWETFWTGGLTNPLEVIEQFTYLLFIKGLDEV
                     ETKNEAEATLLGVSFEKIFDDEHQHLRWSKFSNEGNSEKMYEIVQNEVFPFIKKLHGN
                     KESAYAKYMGDAIFKIPTPLMLSKIVDGISNLELSKDRDTKGDLYEYLLSKVATAGTN
                     GQFRTPRHIIDMIVRLIKPTPEDIIVDPAAGSAGFLVSSQQYLRDNHSSLFLVQGLKE
                     HFNNGMFYGFDMDRTMLRIGAMNMMLHGVDNPNIEYKDSLSEVNTDKDKFTLVLANPP
                     FKGSLDYEAVSADLLKVTKTKKTELLFLALFLRVLKIGGRCACIVPDGVLFGSTGGHK
                     SIRKEIVDNHKLEAIISMPSGVFKPYAGVSTAIMIFTKTGTGGTDKVWFYDMKADGYS
                     LDDKRNEIKDSDIEDIIKRFDNLDGEVDRKRTEQSFFVDVEEIRENGYDLSINKYKEV
                     VYEEVVYDAPSVIIGRVKVLEKEIVDGLEELERMLEV"
     gene            complement(51763..52632)
                     /locus_tag="PC366_000267"
     CDS             complement(51763..52632)
                     /locus_tag="PC366_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HDF2575828.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRVGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDDLDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIREVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKDVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIGTVKC"
     gene            complement(52652..54568)
                     /locus_tag="PC366_000268"
     CDS             complement(52652..54568)
                     /locus_tag="PC366_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HDF2575829.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKANELIQRCIDG
                     KVAIRKGNLSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNATKDGHKNESAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMIGILDKSGVLLDKKKFKEEILKREEISSTGFGMGIAIPHAKTDAVKVPRVAVGV
                     SKEGFDFESEDGSLAHIIFMISATDNGDNLHLKTLSQLSSKLMNEEFLNELLNSKTSR
                     EIVSKLNNEEIKSV"
     gene            complement(54571..55491)
                     /locus_tag="PC366_000269"
     CDS             complement(54571..55491)
                     /locus_tag="PC366_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HDF2575830.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFDVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLDKIQSLADISYLSISGSLPPGIDDNYYEDIFKICKNKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGKSIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVEDYIKNIRVRKVV"
     gene            complement(55593..56345)
                     /locus_tag="PC366_000270"
     CDS             complement(55593..56345)
                     /locus_tag="PC366_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2575831.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTINKSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            complement(56642..57259)
                     /locus_tag="PC366_000271"
     CDS             complement(56642..57259)
                     /locus_tag="PC366_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575832.1"
                     /translation="MNVIKKFIFVILIINILGCGISLILQSSLGSDAITLLNEGIHIK
                     LGISYTIAGLIYNGTLLLIALLLNKKSLGLGSCVYVLVAGIFIDLYIYLLLDFNISSL
                     GIIIRIMSFIIGHILMCSGFAMLIKFDIGMSPLDAILIYIEGKFKYPYKVLKTIADLI
                     FLILGVYLGGNLGFGTIFSILCTGTTISIVSKMISVNKKRYYSSI"
     gene            complement(57347..58804)
                     /locus_tag="PC366_000272"
     CDS             complement(57347..58804)
                     /locus_tag="PC366_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF2575833.1"
                     /translation="MIKLSKFPKDFLWGGAVAANQLEGAWNEGGKGWCLADVHMYDKD
                     RDISKHYESDMTVDKIKFAMKDNNGYYPKRNGIDFYHTYKEDLKLLKELGLKCFRFSI
                     NWARIFPNGDDLEPNEEGLKFYDNLINEVIDNGMEPIVTLLHYETPLNLVLKYKGWSN
                     RKVVDFFVRYAELILNRYKDKVKYWIVINQINLMYHESFNSVAFCVDQVDDVEEAKYQ
                     AIHHQFMATALTKKLGKEINSDMMIGMMMADCTSYPEDCDPENVVFALKRNRIQYFFT
                     DVSFRGEYPAYIKRFFKENNINIVMEEGDDKVLKENTMDFLALSYYYSTTVSASKNTM
                     NPIDNVKNQYLKANPWGWAIDPKGLYNTLSQYYDRYQKPIMIAENGFGMHDKFEDGKV
                     HDSYRIDYLGKHIEQIGEAIADGTEILAYCMWSPIDIVSCSSQEMEKRYGFIYVDIDN
                     NGNGSKERYKKDSFYWYKNVIRTNGEELKEKVDSF"
     gene            complement(58826..59179)
                     /locus_tag="PC366_000273"
     CDS             complement(58826..59179)
                     /locus_tag="PC366_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2575834.1"
                     /translation="MTTEEHVIDEELVEVAMQIILRAGEARTEIKHALNDLERFDYKN
                     ADLKLAKAKEFMTEAHRAQTNIIQGEASGEKRAHSLLFAHAQDTLMTIFSELNITMSL
                     VGIVKSIEYKVNNSK"
     gene            complement(59208..60455)
                     /locus_tag="PC366_000274"
     CDS             complement(59208..60455)
                     /locus_tag="PC366_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2575835.1"
                     /translation="MGRLFMNKFIDLLSEKFTPVVNKITKNIWVQSVQSTIMKVLPMV
                     FVGSLVTIVSVLKNYISFLPDLSPINQYTFGLLGLFIAFLLPMEIMKNKKFESMSVVA
                     GLAGAGLMLMMIRPEITNEGAIFNFNRFGGEGMLVALVAGLFSGLIMSLFGSFSFFGE
                     DSALPDFVSKWFDSMLPIAVIMFIGWGLIYGLNFDMFEIIVRIFKPVSDIAQTLPGFV
                     LLNFLVVFLYSLGISGWVLSPITYAIQLSAIAANAAAVASGGLATNIYTYEVVQTGWI
                     TLGGWGATLPLVLMMCLSRAGRIKAIGRACIVPSIMNINEPVMFGAPVAWNPFLMLPM
                     WIGTVVISITTYLSMSMGFVTIPSKVFNLWYLPFGISTFMVNQDVRGLIVLAINIVLL
                     FMIWYPFFKAYEKEELKLESQEA"
     gene            complement(60463..60780)
                     /locus_tag="PC366_000275"
     CDS             complement(60463..60780)
                     /locus_tag="PC366_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2575836.1"
                     /translation="MKNIKVLLACGSGASTGFMATSMRKSAKKKGIEADIKARSESEI
                     DKYLPEIDCLLLGPHLDYMKDEIQKKADEYNVPVACISKTAYGRLDGVKALEEALELI
                     LNK"
     gene            61028..62941
                     /locus_tag="PC366_000276"
     CDS             61028..62941
                     /locus_tag="PC366_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2575837.1"
                     /translation="MKTSKKELFLNFIKTQHDWIDSSTLANYLNVSTRSIRKYVNEIN
                     STGEFILSSKKGYKVNLNNNCQTKVDSSENISPDNRLNLILKELIVNSNGINIFDLSE
                     ELFVSPATIEGDIVKANKFIGSYNLKIKQSKFLLKLIGNESAKRKLMSSIIFKETGSD
                     FLSLFDVQKIYQEYNLTKLKENIIYILKKYNLFINEYAINNILLHLMITIDRIKKNNY
                     IESVEVVNYIDNNNDISISRDISNFLESEYNLTLTSAELYYLVFQLTNKTTVLNYHEM
                     DTKSLPNYIDEHFVKLTKKIIKNVYDLYFIDLSDDEFVVKFTLHVKNLISRAKNNQVL
                     RNQIPQKLKDSYPLIYDISVYICNQIQILENIEIDEDEISYISLHVGSFFDRQKLLED
                     KILCALITPNYYDLQFKIVRDLEKRFNESIEIIQIFSDTHNLDFDNKVDMVITTLPIS
                     DRCPIPFVYVNPYLNRKDYDNIQSKFIQIKDRKNILTVQNHLEMYFSESLFMKNIYLD
                     SAKDYIKFMGNILYKNKYVKPNYIDDVLIREKMSSTAFNNNVAIPHSMKMDALKTGVC
                     LIVNDKPVKWGEEKVQIIAMIPINEKEKEKFNYIFESFIEILSEWNNVKELTKADNYS
                     SFMNRIAYLIQNI"
     gene            complement(63064..64218)
                     /locus_tag="PC366_000277"
     CDS             complement(63064..64218)
                     /locus_tag="PC366_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDF2575838.1"
                     /translation="MKILISIDSLKGSLSSIEAGNAIKKGILKVKEDAQVKILPLADG
                     GEGTVDALVQGMNGKKETIEVTGPIAKKVDATYGLLKNTSTAIIEIAQASGLTLVPTE
                     LRNPLYTTTYGVGEIIKEAINKGYRNFIVGIGGSATNDAGIGMLQALGFEFYDENNKL
                     VGLGGKVLNEIRHIKIENRLKELDECKFKIACDVNNPLFGKNGAAYIYGSQKGATSEI
                     IEELDNGLRNFSKVVKNYLSKDVANVEGAGAAGGLGFAFLAFLNSKLESGIKIILEEI
                     KLEEELKDADFVITGEGRLDNQTAMGKAPIGVAKLAKKYGVKVIGLAGATTEDAVKCN
                     EEGIDAYFSIVNRAMTIEEAMDKATASENMTATTTQIFNLITSIQQSKNM"
     gene            complement(64500..67115)
                     /gene="mngB"
                     /locus_tag="PC366_000278"
     CDS             complement(64500..67115)
                     /gene="mngB"
                     /locus_tag="PC366_000278"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HDF2575839.1"
                     /translation="MKKNVHIVPHMHWDREWYFSTEESRILLVNNMEEIMDMLENNHN
                     YPYYVMDGQTAILEDYLAVKPECKERIKKLVQEGRLIIGPWYTQTDEMVVGGESILRN
                     LLYGIKDCDEFGEYMKIGYLPDSFGQSAQMPQILNGFDIKYSMFWRGCSERKGTNKTE
                     FNWKSDDGSSVLVQILPLGYAIGKYLPMNEDELRTRMDKYLPVLDKGATTDHIILPNG
                     HDQMPIQKNIFEVIYKLKECYPERKFFLSRYENIFKELEKNKDIDTIKGEFLDGKYMR
                     VHRSIFSTRMDIKSANARIESKITNILEPLASIAYSLGFEYHHGLIELIWKEIMKNHA
                     HDSIGCCCSDKVHQEIMNRFFLAEEKVDQLITFYKRRIVDAMSCEMALDKLVAFNLMP
                     YNRNEIVNAQVITKMKAFEIFDKDNNKLDFEVVHKEVIDAGLIDRQIVHYGNYDSFMV
                     YTINFKDKIPAMGYKAYMIKEVEHMLEKAYEVCDMVDNDFYTIQVNENGTLKISDKKL
                     NKTFENVLLMENGGDEGDEYDFSPLPNEKLIFNDNIVANSTIKKNRFNNEIKINYRLK
                     VPKDIQARKNNRADSFIDFDIVINVPNDKAIINVVFNINNQARDCRVRTYIPTNIASK
                     FSVSDNQFGHIKRSVYDDAMEVWQQEEWSERPDSIYPMLTFVGLSDKEHGVAVLTNST
                     REFEIVGKKFDTIAITLFRSVGFLGKEEMARRPGRPSGIKLPTPDSQMIGDIKIDLAI
                     VTHEKSTLEANVANMAKEYLTKIQTYNKIPYNAMKLNQSEIEVDYSYSLLKETNKDLV
                     LSVVKKAEKEEALVVRFYNSKEETKSANVVFNKNIKTAKWTNLNEKELESISIDNNSV
                     NVECLMNQVKTILVK"
     gene            complement(67259..69184)
                     /gene="mngA"
                     /locus_tag="PC366_000279"
     CDS             complement(67259..69184)
                     /gene="mngA"
                     /locus_tag="PC366_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HDF2575840.1"
                     /translation="MEFKKITNENLVFLKQKIKTKEDAIKFLARKLYDEGKLTSYEEY
                     LEAVMYRETLSPTGFERGLAIPHGKSKSVKEAAFAAMTLETPIENWESVDSNNKVELI
                     FLIAVPESEGGNTHIQILSELVTRLSNEDYMNMLLNSKTKKELFNNLDIKEKKEQIKE
                     EIRIQNESKKIVLAITACPAGIAHTYMSAEALIKAGKEIGVDVYVEKQGANGMVDPHT
                     PDIIKKADAIIYATDVAPKNTERFEHLPNIKTSVAAPLKRAKEIIYEALEVAQKQGKG
                     DYIEKSSDISYCEKSSWKKDVKSAILTGVSHIIPLIVAGGMILAFAVLASQAFGLQEL
                     YNQEGSWLWQLRKLSGGMLGTLMVPVLSAYMSYSLAEKPGLGPGFAAGLAADLIGSGF
                     LGGMLGGLLAGYIVKFLKKNIPAKGTLAGFVSFWVYPVVGSLVVGLLMLFVIGKPVAA
                     LNNGLINWLNGMTGINAILLGAIIGAMVSFDLGGPINKAAYTFAIGAIASGNFIPYAI
                     FASVKMVSAFGVTIATVLGRDLFSESEKEIGKQTWILGLAGITEGAIPFMIEDPIHVI
                     PSLVAGSAITGSIVAFFNIGLQVPGAGIFSLALLEGSMSGFIIASIWFFAAVLGAIIS
                     AILLIITRKQKNQRKIH"
     gene            complement(69314..70039)
                     /locus_tag="PC366_000280"
     CDS             complement(69314..70039)
                     /locus_tag="PC366_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2575841.1"
                     /translation="MEFYERAKKYEYKFTDTEDMIIEYMRKNKEEIVKLSIQSLADKF
                     FTVPNTIVRLCKKMEYDGFSQLKNNLKEELKNEDKEPKNGFESDIKKTLELIDYEKIN
                     KVADIIQKSRSIIVYGIGQNIPLCEILVKEIRGGHDNITYYSQRHEVLHDIGKLGEQD
                     MFFALSLSGETKEVIEAAKTAVNKGCKVVALTHICENQLQQIADISLYCYSTIKQVNG
                     YNISDKVPIMMIMRAIIEQYWLR"
     gene            complement(70302..71081)
                     /locus_tag="PC366_000281"
     CDS             complement(70302..71081)
                     /locus_tag="PC366_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HDF2575842.1"
                     /translation="MHKMKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPF
                     SRQAIEMVKNDDVCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLTGK
                     EVFNYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEEDVSISAMCDAAKEYGIPSCPY
                     YLDSCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSS
                     LIQERVYEHAMLCDKEVKMWLKRNNIELVDFKDIFKSNNYI"
     gene            complement(71074..72501)
                     /locus_tag="PC366_000282"
     CDS             complement(71074..72501)
                     /locus_tag="PC366_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2575843.1"
                     /translation="MMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVPAISNISN
                     IVFSNVDYLFLLGAVSAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNAGVFGGII
                     VGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLSPVVALILSYIFSLLWIYPQAAMNQ
                     FGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTSTGEVIRGEIPRF
                     MAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKKKQEVKGAMTAGALTSFMATVT
                     EPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGARLGSFNGASIIDYVLSFSYGDKAW
                     LVIPVGVVFFVLYYVTFKYIIIKDNVQTPGHEVEIEIGDKVSEKEKNLKLSHGNFSYM
                     AKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLSNTSVQII
                     IGTDVVKVKDEMEMQLDELRKQADA"
     gene            72892..73614
                     /locus_tag="PC366_000283"
     CDS             72892..73614
                     /locus_tag="PC366_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2575844.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECIGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            73811..75478
                     /locus_tag="PC366_000284"
     CDS             73811..75478
                     /locus_tag="PC366_000284"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HDF2575845.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLYSLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMSDFEKLLKEAHKRDIKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDETTNQYYL
                     HLFEETQADLNLENEKVREECYKVLEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGAKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNAY
                     YHMIKSGIDEKEALLILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSRSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNLLVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDIIENKMEIKPYESIMIYYK"
     gene            complement(75574..76893)
                     /locus_tag="PC366_000285"
     CDS             complement(75574..76893)
                     /locus_tag="PC366_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2575846.1"
                     /translation="MEKGIKLGFWSIVLLGINAIIGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGDFVGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQAAEPLIKNIIIGILVVGLGIINFMGMKQSKHLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSASSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSVIYMLILGISIGVLGNGLAGSATPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRKTNKNGAPYIAIIVSVIGTLL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYADKDVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYSKKYNDVEVK"
     gene            complement(76934..77680)
                     /locus_tag="PC366_000286"
     CDS             complement(76934..77680)
                     /locus_tag="PC366_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HDF2575847.1"
                     /translation="MKKLVKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CKAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDVNPLIWKEEPHNKLGAISPKRDSF
                     DMKLLKHALDMKKPVLGICRGEQIINVTEGGSLYQDLSLIEGAYIKHNQQHLSNVPTH
                     TVQIKEGTKLYEILGEKEVLVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTRDYDNMKKIFMAIVKEASK"
     gene            complement(77924..79933)
                     /locus_tag="PC366_000287"
     CDS             complement(77924..79933)
                     /locus_tag="PC366_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2575848.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEEIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGESSLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGMAMVSDKGNIIICNNSLRDILDIQSNIIGKNIDELENENIKKIFSLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSTKMERTKKLGMKIAESDYTILITGESGTGKELMAQSIHNASPRHSQSFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKGDRFRADLYYRINVLPINIPPLR
                     ERKEDIEVMLKHFMKRKRAISQGVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     NDLPHNLLNITEDFSKEISILKDRTSIEKVKLVMECLKNANNLNKNIGRNGIVNSINE
                     LGYSITEGEVRGILNMLKELDLIICESGRKGSELNRRGKNILNSI"
     gene            complement(80371..81804)
                     /locus_tag="PC366_000288"
     CDS             complement(80371..81804)
                     /locus_tag="PC366_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF2575849.1"
                     /translation="MVLRKDFLWGGATAANQCEGAWNLDGKGPSCSDMCTGGSQKVSK
                     RITRVIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEIPFAITEKYNGWVSREVIDLYMNYCETIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFINQVDIPQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPDDAVKTQRDSRVMNYFCGDVQVRG
                     EYPTYMNRYFGENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSDSKEDNTSGNI
                     LGGVKNPYLKSSEWGWQIDPEGLRYALNEIYDRYRIPMMVVENGLGAYDKKESNGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMTKRYGFIYVDKYDD
                     GSGDLSRIKKKSFDWYKQVIESNGERL"
     gene            complement(81891..83807)
                     /locus_tag="PC366_000289"
     CDS             complement(81891..83807)
                     /locus_tag="PC366_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2575850.1"
                     /translation="MRRYEQLSKEIIENVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSAGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSDSDAPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASIGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVIIIVLLAAKLEKVFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGVLTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGAFVPSFAQTSVVAAMYFKLKDKKIKELCIPAVISGICGVIEPAIYGITL
                     PRKTPFIYSCVGGAVAGAVMGIMNVKSYVMGGLGIFGIPNYINPTTGDMKGVYATIIA
                     IIVAIVVGFVLTLFFWKDDSIVEISKDNNGQGVVEKNKREVVYSPIKGEVKALEQIQD
                     AAFSTGILGKGVAITPKEGKVVAPFDGTIMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKHFKSFVNQGDKIKKGQTLITFDIESISKEGYCLETPVVVTNYSDYVDIIENTQ
                     KHVNNSQELITVLA"
     gene            complement(83881..84741)
                     /locus_tag="PC366_000290"
     CDS             complement(83881..84741)
                     /locus_tag="PC366_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2575851.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGEHISKDKI
                     DKIFKLSDPNISDKFKELIADIPIRYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVSVKNVLLWDIKRFYKSEFKIGLEALDYIEKKFEIRLSEDEAGFIALHI
                     VNAQMDQSIKTIYEITQIIQEISNMVKYHYRIVFDEDSVYYHRFITHLKYFAERIVSN
                     NLHENNEDDLLNVIKVKYKNAYKCIEKLDEFIHKKYNYDLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(85092..86279)
                     /locus_tag="PC366_000291"
     CDS             complement(85092..86279)
                     /locus_tag="PC366_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2575852.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VEKMKEYGFDTVYPYCNMETAFRAELGDNDGPTIAFLAEYDALPGYGDNKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIESGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDISPMVYVHEKEFLNYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(86293..87684)
                     /locus_tag="PC366_000292"
     CDS             complement(86293..87684)
                     /locus_tag="PC366_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HDF2575853.1"
                     /translation="MSSLKKKKFTMPQTLTIIFSLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKKFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQIVPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQESMVNSDTNIKEFTKREAMVIAIFTIGMAIMIYGVLRL
                     EWYITEIAMIFTAIGIISGIASGLKQDEIVNSFISGAGDLITAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFVIPLMVVLTIL
                     VMVFLTIGLYLGF"
     gene            complement(88279..89979)
                     /locus_tag="PC366_000293"
     CDS             complement(88279..89979)
                     /locus_tag="PC366_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2575854.1"
                     /translation="MHYIAWHFNKNGGNNTMKDKLQVLSGAMMIPVILLVVAGVFIGL
                     GSAFANMENVSALGLSGLIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKK
                     EKGWGALGGIVLFIGMHTVISTLLASNGINSDTVTAEAFMASGLGEAEAYSRSSLYGS
                     FLGIFSYDCSIFGAIIAGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLG
                     TAMYFIWPPVGLALSKLGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVG
                     GTMEVGGAIYEGVNNIRLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLAD
                     NANKKKAISILIPAIVTAMLVGVTEPIEYTFLFVAPLLYFVAYVPLAGLTYVFTEMFN
                     VSIMGESFRNMFPNLLQPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSE
                     EVKLYSKKEYRERQSVDAGKTAYNNAVEEEVDDKDTKLVHSIIEGLGGSNNIKNVTNC
                     ATRLRVELNSIDGFYEDGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD
                     "
     gene            complement(89951..91354)
                     /locus_tag="PC366_000294"
     CDS             complement(89951..91354)
                     /locus_tag="PC366_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2575855.1"
                     /translation="MIVNKELIIDYLKSNQENIIKDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIQIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGENGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTDDKKDLVESLAYYTEIEELEEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLEKIKKLNDKGVIIRDILNSYFTDDNHGKKLGIYKEDVDMGVSTICIMS
                     IFLEKNELNMKIDFRYPKGISWEFITNRINEIGKKENLIVDIYKDLKLLYVKPDSELI
                     NKLSSAYKQGFGKEAELFTKGAASYARVLKNGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
     gene            complement(91618..92109)
                     /locus_tag="PC366_000295"
     CDS             complement(91618..92109)
                     /locus_tag="PC366_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2575856.1"
                     /translation="MFNIFKKKENKIEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPNEGKLYSPVDGEIVNVFDTKHAIMIKSNDNTNILIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEVDLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            complement(92135..92947)
                     /locus_tag="PC366_000296"
     CDS             complement(92135..92947)
                     /locus_tag="PC366_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2575857.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEAMEKGIKVALVTG
                     RPYNAMKYFTSVLGDDIYIISTNGTYFKLMGYEYKKVLSKEAIKKIYTIGEKYNLNKH
                     FKGCKIVISNNEIGEEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVDSLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSKEVIC
                     IGDNENDISMIKFAGLGIAMGNATDEVKSMADFVTDTNVNDGVAKALRKILS"
     gene            complement(92960..94111)
                     /locus_tag="PC366_000297"
     CDS             complement(92960..94111)
                     /locus_tag="PC366_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF2575858.1"
                     /translation="MINFYQPSRINFGQGTLSELPRIIGKYGKKCLLVTTPNVEPLDK
                     LYKRVTLNLIEKGIEVVHFDRVEPNPTVELINEGFELAKKESVDVVLAVGGGSSIDTA
                     KVLALTFGLEKIDWDYMFSTYTNPFKIYDKVSEKELPLIAVSTTSGTGSQVTQAAVIS
                     RGSEKNTIFHQNCFSKECIVDPELMLTLPERITASTAFDAFTHAFESYINPNANDFTE
                     IMSEKSMELVINYLPKVMEDKNNIEYRTKLAVADTLGGSSLANAGAAAPHPLSEIIGG
                     VTHIPHGEALAIVFPKFAEKFYKDNIEKFAKVARMLNQELEKVEDDEAAKTLGNEIES
                     FLKRVGLKTKMSEFNVTKEQLEQITSCPVLGFLPFGKKEDLVEILEKSY"
     gene            94381..95022
                     /locus_tag="PC366_000298"
     CDS             94381..95022
                     /locus_tag="PC366_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HDF2575859.1"
                     /translation="MKYLIDSANLDEIQKCLKYGFKGITANPSMYLKEKVNFHEFIET
                     CTNLNPEILTAEVIGNNLYELINSCDKILNINKNTIIKINFSEVGLELINILNSKGVK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICNLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTVDGANTFERDWSKVNK"
     gene            95048..96592
                     /locus_tag="PC366_000299"
     CDS             95048..96592
                     /locus_tag="PC366_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2575860.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEELKVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AVFELATVNKSYTELKEILFSNSNECKDTPSTKIFKELFNYDFEKLSQITLHTLQVEK
                     SNLSDEYYINFLIHIAICIKRISIKRYINLSEGFFRELLEHEYFEKSKILCANLSEAF
                     DVEFIDEEVCYILLHIEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGSILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(96809..97435)
                     /locus_tag="PC366_000300"
     CDS             complement(96809..97435)
                     /locus_tag="PC366_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2575861.1"
                     /translation="MKKEMIKDYLLITISAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPLFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINNACAQ"
     gene            complement(97570..98286)
                     /locus_tag="PC366_000301"
     CDS             complement(97570..98286)
                     /locus_tag="PC366_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentose-5-phosphate 3-epimerase"
                     /protein_id="HDF2575862.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTIGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRADNMEPLIECNPDVVILSSAIFKDKDGIT
                     AGVKNCRKAIDEAATKFGLE"
     gene            98701..99915
                     /locus_tag="PC366_000302"
     CDS             98701..99915
                     /locus_tag="PC366_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDF2575863.1"
                     /translation="MRNCIIAQSGGPTAVINASAVGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYKINSYDYDRVINILDEYEI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFIVETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASDTDLKQAAEVGAYGIELSKKGYTGVMAII
                     NRTCNNPYKYEVSHTDISKIANKTKYFPKEWINEECNYITDEALNYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            100534..>100761
                     /locus_tag="PC366_000303"
     CDS             100534..>100761
                     /locus_tag="PC366_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575864.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIEIYIYRDFSHVGDLY
                     LEIEDRFDGFAVSGPIPKKAITKKAGTIKKPL"
BASE COUNT        32960 a        17810 c        10747 g        39244 t
ORIGIN      
        1 tttttatctt aattttctaa atataagtga atgctatcat tttaagtatc ttataagcaa
       61 tgtaactata tatctctaat aactactttt ttaacatgct taaactattt ataagctatt
      121 atatttatgt attaacctaa taactttttc actaaaaaat aacaatctat tcaaagataa
      181 actatagtac ttcttctact ttgtttcaat aaaatactaa ataaatttcg tacatccaca
      241 atttttcagg ctacactata aatatacaat atttatctta gttataagtt taagaatatt
      301 tttagtctta ttttgtcgaa tatattttta ataaaacttc ataattctaa gcatattttt
      361 acactgtgtt ttcatgtaca aaaataatgc ttacaaataa acaacataaa taaaacttaa
      421 ataagatgga ttctattcaa catagtatcc atcttattca ttcaaaacct aaaaggattt
      481 tttataatat tatatatttt aaaatctaag taactcatta tagtatcaat ttcacttaaa
      541 gcttacaata cacttattaa tcttgcttta tattaaaaac atctacaata acaatttaaa
      601 tctttaagtg atatccatct cacacctaaa ggagtgggct ctccgcacta ttctgtaatt
      661 cttcaataca atcattctta attttttata taatttaatt atatatttta ttttaccaaa
      721 accagcatac ataaataata cttaaaatag attaaataaa ggatactaaa acactttatt
      781 gaggtatatg acttgaaata tatgaactaa cttcattagg agaaatatct aaaatagttg
      841 caaattcttc acttaataac ctttctgctt ctttcattat attatcatct gcttgatgtg
      901 tttttttacc aatagatttt acatactctc tgttattatc tatacttctt actaatttta
      961 ttaactcttc acatttacca cctctgagta tttttttaaa ttgctcactt cttaattttt
     1021 cattatctat ccatgatgta tccatattag gaatatcatt tattaatgaa agcacattaa
     1081 ttttagaaag taactttctc attggtactt tttcattatc tacaggaatt tttattactg
     1141 tattattaga ataaatagga ctcaatacat aatactcttt ttttattcca tttgtaaatc
     1201 gttcatttgt tatatccatg actttgcaga ctcctgtcat accatacatt atataatcat
     1261 caatcttaaa caaaaacatc accatcctta ataaaaaaaa tagttttgac aactaaatcc
     1321 atcttgccaa aactatctgc tatatattat attttaacac attttaagac ttaaatgtaa
     1381 gtaaaactta tattattaaa attaaaaaat acattaacca ttgattaatg tattttttag
     1441 atttttataa caagcatatc aaaataaatt aatacagctt atctcctgtg aatacctata
     1501 aaattggtgc ttggctattc attgagtacc catcatttct tacatcattt atttctaata
     1561 tttcatcatt tgttttaacc ttagtaagtt ttttaactgc tccataaggt tcttttaatg
     1621 aaattttatc tcctcttcca gaaataaccc ataaaatttt ataccctcta ggtattactt
     1681 gtagtttatt ttcaccttta ccatcagtaa agtagactaa caaattaatc tttttattat
     1741 tagcatactc aaagactgga gaaaatctag tacctccacc tatcctaatt ctatctttta
     1801 tatctttttc agttctcact ttatatacac gtctaatttc attatcacat tctataattg
     1861 taatttcatg attatagttt ttcactatac taagaacttc tttaatagct tgtttaaatt
     1921 cttcatcact aatacttcca cttacatcaa gtgcaactgc tatttctgcc ttatgacttc
     1981 taagttctcc cctcaaatct aaacgatttg gttgtcttct atttcttctt gttatagtct
     2041 tctttttatt attttcaact gttcccatta ttctattaag atataaattc catggcaatt
     2101 cacccttact atttttaagt gatgatatca tactttctaa ataagcagga actttacctt
     2161 tttgagaact gttaataaat ttttcagtaa attctctaag ggtattttta tctatctcat
     2221 tggattcatc ccatatatca tgagttcttt cggggctata atcaatttct acatctccat
     2281 atttatcact atcatcttcc tcaccatctt catccacttc catcaaatct aattcagtct
     2341 gaatcttttc tacataatat tcaaaaggtt catatggttc aagttttaag gaatatttta
     2401 aatttaccca ctctaaggta gttgcatatg gtggtaaatt gtttagaaat ttatttacta
     2461 ctatatccat tgccatatta attgccaatg tactatactt tccttttaac tcctttgctc
     2521 tcatcaaatg catagataat atatgatgaa tttcatgttt aattgtagtc tccatttgct
     2581 ttatgtcaag cgttaaaaag attattggat taaaatatat aacatattta gctcccttaa
     2641 aattcacgcc tgtaggacta cttatatcaa atcttatttc tcttgacatc tgaaacaaaa
     2701 aatatccata aaaattatct tcttcttcca taagacttaa attcacttta tctacaagac
     2761 taaaaaactc atacttaaaa tcttgtggta tatccatatc aaatttctca ttagcacgat
     2821 ttgcctttag catagaatga gtatttataa tttcacttgc tttattataa agctcttttg
     2881 cttgtttatc aaaataattt tccatacatt atccccttat taagctataa gattcaaaat
     2941 atgattttac aaaaccttca ttttctatgg cttttttata tacttcaata taactgtttc
     3001 taatatcctt cataatacct atcattaaat ctacaggata catttttaaa aattcaataa
     3061 atctattaat atagtggttt gattcatatt tatcattctt aatatttaat tctaagtctt
     3121 ttagaatgtt catagctgat agataaagtc ttgtatgact ctcatttttt actctttcta
     3181 caatgggctc atcaatagat tctcttaaaa aaacatcttc ataggatatt aatggttcag
     3241 agtttgattc aataaaactt ataaattctt ctgcaataac tttacctaca ttacccttta
     3301 caacatttaa aaatactgct ctaggaatag aattattttt ttctttataa actttataaa
     3361 ttttagatac tctctcataa cttctaggag tagctcttac atcatcttca tttattttat
     3421 gcagatattc tggaaaagtg gaaataaact cgataacttt tctttcaata ccctcatcta
     3481 ttgcccattt tatccattgt gtatggtcac tctccatatt taaccaaaca aacctatttt
     3541 cttgggctgc atccatatct accacttgat aatcaaaatc tgaaccatat ttacttgatg
     3601 gattcattgc tgctaaaatc tttacatcat catgcagttt atatccatta atttctctat
     3661 ttaaaattaa attcataagt tcttgctgta ctgtatgctc acaacgattt atctcatcta
     3721 taaataaaag aactgtctta cttttagata tctcttcatc aatttctctt aatttgttat
     3781 gaacagcata cactgttgtt ttcttttcag tcttatatcc attagaatta actcctacat
     3841 aagattctat agttggaaga ccacctattt caccctcttt aagtaagttt ccatcaataa
     3901 caattaaact ccaatcattt tctttggcaa gcttatttgc taaagctgtt tttcctattc
     3961 cactttcacc tactattaaa ggtacttctc cagtggataa tattaagtca acgcttttta
     4021 atgtgtctat aaaattcatt tttctctctc ctacataatc tttaatttct catctacagc
     4081 tatttttttt gctgtcttac ttccatattt ataaataaac ataattttat ctattggtat
     4141 actttcgcta tttctatcta taacactaca attcaaaaaa tctctaatat acttttcctc
     4201 aacatcttct ttggataata cttcttttaa tacactctct aattcatctt tagatacttt
     4261 tttcagaatg tacttaatca ctaaaatatt cacttttaaa aattccaaca ttttattttt
     4321 atctaaatca gttataaagc taatagctgc ttcattattt tttatagcta taagttctgc
     4381 attataacta ggtgaatcta tatatctcaa ggcatcataa cttattctta ctgcctcctc
     4441 ttgtacactt tcataaggtt gttttataaa ctttatcgaa tcataatttt ttcttactgc
     4501 taacagttgt aattcttcac ttggattttt agcatattta attgcccatc ctgcttgatt
     4561 tatagccatt tcaataactt tatcagttgg gtttttgata taatccagta tactccatcc
     4621 ctcatttact gcttttatca tcatatcttc tgttggatta tctataaatt taattgctct
     4681 aatattatta tctattgcta gttcttgcat ctctctggtt ggattattta tatattctag
     4741 tacaagccca ttttctttaa tagctaacaa tttcatttca tcagttggat tatctattgt
     4801 agctataata ttgggattat tttttatcat ttcaataact ctcaattttt ccataatgtg
     4861 cctttctttc tataattatt tttatatcta tattaattat aataatctat tcctatttat
     4921 ataattgttt cttattataa ttaatatact ttttaatcaa atttaaacag aataattata
     4981 ccaatatata aaaaaatttc taaaaaacaa taaaattaag ttataaacac caatatattt
     5041 ctattatttc aataagtata caattagatt agaatctaac gctagtaata aaaaattact
     5101 ttcccaaaat agatataagc ctcattttat cgttcaaata atgaaaatat atttgatttc
     5161 atgcaaaaag agtgcctaat gaactaaaaa gttcattttg agacactcat ttctttatat
     5221 aaatttatat agtttttaat cgttcgcatt caaccactca gttaagactt ttatatattt
     5281 ctcattttct tcaacgaatg gcatatgtct tgaatactca aataactccc acttactatt
     5341 aggtattcta tcatacatag tctttgcaat atatggcgaa cataaatcta ttgctccact
     5401 agttactaga caaggctctt ttatttcatg taatctatct gtaaattcat atccagaaag
     5461 agttcctgta ggagaaaatt cattttgtcc ccatcctaca atatatgctt cagaacctga
     5521 ttttttaggt cttctcaggc actctggaga atcttctgtc acttcacctg cacaatacat
     5581 ttccataaat ctttctaatg catcattata ttctttatta gagtaatctc cagtatttac
     5641 tgcatcaagc aatgcttttt ggtcaacctc actcatatat gatattcttc ttttttgttc
     5701 tttctcccaa agttttgcag aagaaagagt agatgaaagg atgtaagact taataccttt
     5761 tggtttatat tcaatagcat accaaatagc ctgcatacct ccccaagatt gacctaacag
     5821 atgaatttca tcaagtccta gatgttttct tagttcaata agctcctcta tccaagtatc
     5881 tgcattaaat aactcaggat gcccttctac aaaggaattt ccacaaccaa tttggtcata
     5941 cattattact tgtctaccac tttcagctat cttatccaat acctcaaaat agttgtgtgt
     6001 agaacctgga cctccatgaa gtaatactaa tggcttcttc ccttccgtat tttctcctac
     6061 tatacggtaa tacgttttaa aacctttaaa aggcatatat ccttcagtaa ttttcatatt
     6121 tatctcctcc aatttgtaat tataaacaat aatcaagttc attaacaata ctatttaaaa
     6181 cctctcatac gtatttaatt atgtctttta atctttatac ctacttttat aaatagtata
     6241 acataaaagt taaaaatctc tatactaaac caattataaa attatattaa ctatataatt
     6301 ttatttttta ataatagtat atacatattt gattattttc atttgctatt taaaatcaat
     6361 tttaagtttt cttcttataa taaacttcct ctttgtggtc tcatgttagt ctctaaattt
     6421 aaaattttac aaaaaatttt cataaaataa aattatattg attgtatcta aacaaatagg
     6481 gcaataaaat aattaagtat agttacttac ctttcaagca atattagttt tatgttagaa
     6541 ttttattata ttgatttaca ggaggtttgc atttgaataa tattaattca cttaaagtaa
     6601 taaaattatc tcttggatgt tctcttgcta tattcattgc ttggctatta aaattagaat
     6661 attcaatggt tgctggagtt atagtactac ttacagtaaa ggacactaaa agagaaactc
     6721 ttaaaggctc cattggaaag atttatggtt ttcttttatg tactattttt tcatatttat
     6781 gttttaatat tttaggatat aatttgactt cattttcaat atttatattt ataattatac
     6841 cactttgttt tttgttaaat attcaagatg ttattgctat gtgtgtagtc atagcatccc
     6901 attactacct tcaaggagaa acttctatca aatggatttt aaatgaagct ggaatatttg
     6961 cagtaggaac tggaataggt gtcttaataa atatgtatat tccaacaaat atacataaaa
     7021 tccatgaagt tcaaaaaaag ttacaggaag aagtgagtat tgtacttata gacattgcag
     7081 atattattgt aaatcctaaa aaagaaaatg gatatagtag agatttatat aaattaaatt
     7141 cacttattga cagcagtatt tctgaaactt acgataatat taataatact ttattaagtg
     7201 atactagatt cttcttagaa catatggata ttataaaaag ccaacgggat atcttagaaa
     7261 atttgtatag ttatgtatct caactaaatt ctacaccacc acaagctcac attctatctg
     7321 ctttcataca taaaataggt tatactgaat ttgaagctga aacaggcaat cttcttcttg
     7381 aagaattgaa gagattaatg cttagtatga aaaaccatcc tctacctgtt gacagaacag
     7441 agtttgaaaa cagagctatt ttattcctat gcttgactga gttaaaacaa tttttagtta
     7501 atcgtaaaca tgctcagatg cttagagata ataattttta taaataaaaa ggtgagaaat
     7561 ccagcagttg acctgactac aaaatatcag atataatatt aaatgcgccc ctagtaagag
     7621 ggcgcgatgt ttataactta ttctactgtc atgattaaat cattattcat atcgaatata
     7681 cattatttga ccaagtccaa tattagcttt ttcatcagtg atttctattt taatagtcac
     7741 atcatttttt ttacagtact ttgctaattc tgcaccagaa cgatttttac cactaaaatc
     7801 taaagaaaat ggcttatcat atttaaaagg atattcaaca ggttcacctt ctggtgctaa
     7861 tgcaaacatc ccatatggtg tgttcataaa tcctattaca gcaattgtaa gatttgatgg
     7921 gtctaaattt gatttactac ctagaaatgt aactgtattc actgatgaat taattacaac
     7981 acatctaaca ccttcataca ttacatgttt atcctttata tctccaaatt ttccaacaac
     8041 ctttgccccg tcttgatgtg gtaacatagt gtgcttccca ggtagtgctg gtttttgcgt
     8101 ttgtgctact gctccaactg ttggatatgc tgtcttatca aatggtaatg ggtggctaag
     8161 actcttgtat atgatatcct ttcctgctga tttattagca tcaatatcta catgatacaa
     8221 acgcccatca ccaaaacgta taagattcca ctggtggtca tttgatgtgc tgtgtacata
     8281 ataagattca attcccatag cgtcacacaa agctttcatg ctcctagcca ttcctgaaca
     8341 tgcacctttt ttagtaacca atgtataggc agtattcgct ccttctactg cattccagtc
     8401 aacatatgtt gtgttatttt taatgtgatt ataggcaact aaaatcttag cgtctgtagt
     8461 catgttcttt gtaattttat tgttcataaa atctgctgtt gcttgtgcta ctgagtttag
     8521 ttgggcttgt gacagctttg gaccatatac gctattggtt ccagtgacat agctttttgg
     8581 tgtttttgct gttacctctt tggctgtcat accataaact gtcatactca tacctgagac
     8641 taaaacaatt gttgtaatca ataacttggt agctaacttc ctaattttct tcatacttag
     8701 tattctcctt tataaaatat tgttacttcc tattctctac cattaataaa gttcatttgg
     8761 gatttaaaaa ggtggattgt caatatgtat gtttcttcat ttatacgttc gtgaaatatt
     8821 taaatttcat ggaaaatcta atagatattt tctagataat ttgtatacaa tacaactcgc
     8881 aaatcagggt gtttgctgtt agtttgagaa aatgatgatg attaatatat tcggaatctt
     8941 tgacctataa taaataccat tgtcttcaat cattaataat ggtaagagta aagagaatta
     9001 tcaataatac agttaaaatc aactttgtat acatttcata cattctctcc caacaacatt
     9061 atacttctta taatttgtat attcaatacg ttttctggga aaatatagga tatatctata
     9121 aaaatataaa aaaggagttg aacttaaaat ttgattaaaa aaaatcaatt ttaagacaac
     9181 tcatttgtat tataaaaatg ctatatatta ttattaagta agtcaatatt ttagatattt
     9241 atctatttct tattgactta cgcttatagt ctaacttatt tgtttagttg atatataacc
     9301 tagttttaag cattattaat atttaaataa tcaagtatcc tttttgtttc ttgtagtttc
     9361 tgttctgcct catttaagtt ttcttgaatt atagaaatat atattatatc tatcaacgta
     9421 agcattgcta ttcttgaaga aatagctcct tctctaagcc ttttttctat atttggtact
     9481 actagcttta aatcactaat cttactaaga tgattgtcac tatatttagt tatacaaatg
     9541 accttacatc cttttaattt tgcattttct atagacttta ttacttcttt tgattctcca
     9601 gagtaagata ttgctatagc tatatcttct ttatctacat ttgaagatac cataagttgt
     9661 gtatgactat ctaaagaggt aaatgcctgt ttatttatcc ttaaaagttt catctgtaaa
     9721 tctagtgcaa ctaaagccga accacctact ccaaatatat atacattttt agcctttatt
     9781 atctgttcaa ctgcttcttt tattatatct ttttcattca acaaccttgt ttggttgata
     9841 gtctctatgt ttttgtttgt aattttgttt ataacactat ctatattaca atcatagttt
     9901 tcatctacat atgtgtattc attttctttg cccatcaaat ctttagctat ctcaattttt
     9961 aaatccccaa aacccgaata tcccattttt ctagaaaacc taactatact tgctgtactt
    10021 gtttttgagt ttgacgccaa ttctgataca gaaagcttac ttatagcctc tgtattatta
    10081 agtatgtaat cagctatttt tttatctact tccgttaaat cttcaaatat ctgttttaat
    10141 tttaaaatgc aactcatact ctaccacctc tacctattta ctataatatt tcttcttagc
    10201 aagtaaacat gctcctaaat ctggagtcaa cactggtctc actataccaa atctcgtttt
    10261 attcaaatat tttttaagtg gctctaatat taaatctcct gacttaaaca ctccacctga
    10321 ataagatacc tttatctttg taccttgttc aaaatgatgc tctaatccta ttataagcct
    10381 acttaattca taagctgcat catcaaatat tttactagca gtattatcac cttcaataac
    10441 tgcttttaaa catatcgtag caaactttgc tatttctatt ctatctcctt gtattccatc
    10501 atttacatat tttattatgt cataatcatt ctctatatta agatgtcttt ttattaaatc
    10561 atataatttt gtctttgaac accttccatc agactgcatt gtgaacattt ttaaggtagc
    10621 cattcctata taatacgctg aaccttcatc tcctaataca tagccccatc ctccacatct
    10681 gtgaagattc ccatctttat ctaaagcctg tgctattgaa ccagtacctg caattatatt
    10741 tatacctttt tccccattta aagaacctgc taatgctatt tctacatcat tacctagagt
    10801 ataatttata tgactatatg cattttttgt tgctacttct aatgcataca atacttcttt
    10861 tatttttcca tatccagcaa gtccaacaaa tgcatacgtt atttcttcta catttatctt
    10921 agcatcttta caaacttctt ccaacccagt tattaataat ttcgttagat tatcaaatcc
    10981 tatttgatta taatgacaag ttcctttggt tatggttcct actatattta attcttcatc
    11041 tactaatgta aatgttgttt tcgttcctcc accatctaca cctaaaaaat acatactatc
    11101 ctcctacaat atctttaata attctttcaa tacttaatat ctaaaaataa ccttccaatg
    11161 ctgttttttt aatattgaaa ggttatcagt actattattt attttacaat ttttctattg
    11221 attttaaagc ttcacttata taaccttctt gtctatctag gatactcttt gcactatcct
    11281 tatctaaacc actttttatc ataaatatag ccaatttaac tctattatct gcttcttcta
    11341 agaatttttc tgcaacgtca tattttacat ttgtagctat cattattatt ctttttgctc
    11401 tttcaaccaa cttttcattt gatgtcttaa catctaccat caagtttgag tatacttttc
    11461 ccatcttaac catagaagct gttgttaaca tattacatac cattttttga gctgtaccac
    11521 ttttcattct agttgaaccc attattactt ctgcccctac tataatgttt attggtaaat
    11581 ccgctttttt actcatttca ctattcggat tcatagttat tgatagtact gcacacccca
    11641 attccttagc atactccatt gcacctataa cataaggagt ccttcctgat gcagctatac
    11701 cacatataac atccttagat gtaactcctc tatctattat atcttgcttt ccaagttctt
    11761 tatcatcttc agcaccttct attgctttaa atattgcttg atttccacca gctattatag
    11821 cttgaacaag ctcaaaatcc actccgtaag ttggaggaca ttctgtggca tctagtattc
    11881 ctatcctccc actggtacct gctcctatat agaataatct acctccctgc ttcattctat
    11941 ctactattat attaacagct tttgctatac tctccttttg ttcttcaaca gcataggcta
    12001 cagttttatc ttcgttattt attaattcta ttatgcctaa tgtatcttct ttatctattt
    12061 gcaatgtatt cttatttcta ccttctgtaa ctaaattttc taaagttttt attaacatat
    12121 catttcctca ttttcttaat attaaatttt taaacacatt ttaactccaa ctttcataat
    12181 tatattttta taataaatta atattttcat aataaattat tttgttgagg gtttaaaatc
    12241 aaacttttgc catggtttaa tataatctaa tataaataat tcttcttttc ttatatatcc
    12301 tactacattc gatttaccac tgtttttcat atcagtcaag gctatttgta actcccctgc
    12361 ataatgacca tattcactac tttcaattac tatatctcct ctttttatta ttttaggagt
    12421 attaaatagt tcaaatttgt atcctttata tttaacacga gattgagtag accttatcag
    12481 actgtcagat atatcccctc tattaaaatg tatttcttca aagagtatct tcttctcaac
    12541 ttctcgtata ttttcctcta ttgctacatc aaatgtaacc atatcttttc tcatagaacc
    12601 taataccttt agctcctcat atgttggata acaatttgat attattatat catttatatt
    12661 attcatagct attatatgct ttacttgaat atctataggt agatttctgt gcatctcaat
    12721 tgttggaagc ccatcagtta caggccatgg tccaaatgtg gtttcatttt gacttgttac
    12781 aaaaactgct gttcttaatc catacttatt aaatctttct gtacatttta taaagtgttc
    12841 taaatttaat ccactatatc tatgtggata aaagttatga catcctgtca aattttcttt
    12901 atttggttgg tagtccatta ttgtatctat ataattagta ttattactca tattgatttc
    12961 tattttaaga ttttgaggat taaaagtcat taaggccttt tcagaacctg taaatcccat
    13021 atcaagcctt attccgtctg ccttcgtctt tttaaaaaaa gtcaaatctt tgtagcttat
    13081 ttctaattca ccaaatactc tgggatttac atcaagtatt acctcaaaac ctttaaactt
    13141 agcgtattca tttatacttt taaatttttt aattatattt tctttagtat ctttaactga
    13201 taataaacat gaaaatatac gtgtaaatcc attttcagca gctttatcta tataatcata
    13261 tatttcctta gatgttgttt tttctggata aattgatatt cctaatcttc ccatctgtgt
    13321 catctcctta tatcctatat gtgtttaaat ttatttcgaa ttacacgaaa cttttttaaa
    13381 aatttggtga aaaaaagttt catatatatt tataaaaaaa gaaaagttta ccttttcttt
    13441 ttttataaac aatcaacaaa atatcttcgt tacttatttc ataactgtta tactttgaaa
    13501 tttatactaa tctaatatag tttttaattt ccaatatagt ttctaattaa taagcttctt
    13561 gctcttcaac tttttcttca tgaagcaatc tcttatcgta catcttgaca aatggatagt
    13621 aaattattat tgatatagct atacataata agttaagaac tgaagctctc caatctccac
    13681 cagtggctaa atatgcccct actggtcctg gtaatgtcca aggagcagta actactactc
    13741 tggatactaa attagcactc atagcaaacc atgaaactgt tgccattact attggtgcca
    13801 caacaaatgg tattattaat attgggttta atactattgg tgctccaaat attattggtt
    13861 catttatatt gaatattgct ggtattacag ttgcttttcc taaagacttt ccataagctg
    13921 attttgctct aaatgcaaga agtaaagcta agcctattgt agctccagaa cctccaatcc
    13981 atataaacca ttgaaaaaag ggttcagcag caatacctgg aactgcttga cccgcagcat
    14041 atgaagctgt attagcatct aataattgta tccataaagg tcttgccaat gaacctatta
    14101 ttgatacacc atgtattcca aatgaccaaa aaaacgttat taaaaatatt agtataatta
    14161 ctgatggtaa tgtgtcagtg gctgaaacta atggagttac taatttagct atgaagccat
    14221 gccaatcaaa ccctaggaaa taagtaacaa tagccattaa aattattatt aatgcggctg
    14281 gtgtcagagc ttcaaaagac cttgtgactg atgctggaac tgcttctggc atggttatct
    14341 tgaatttaga tttgtcagta aatctataaa tctcaacacc tattatagat gttacaatag
    14401 caacaaacat tgaacctcca ccaagattag ccattggcat ttgccatcct tgaggaattg
    14461 aattatacca agctaaaagt tctggactct tttcaactat ctttaataaa tcaggggtaa
    14521 gaccctctat tgcagtagga actattgtca aaaggaatgt agctgtagct aataaacctc
    14581 ctgtcaatcc atctaactta tatgactttg ccaaactata acctatgcca aatgtagaat
    14641 atactgatat aataaaaaat gtcattctat atggtagtaa tattgtaact gcattttcct
    14701 ttagatactg agttaccccc catgaatctg gtaatggagg aaatgctaat atcaagaaaa
    14761 atgacccaac tattataagt ggtaatgaag ctacgattcc atctcttaca gctcttaagt
    14821 gacgttgttc tgccaatctg gccatagaag ttgataattt actgtctaaa aattctgtaa
    14881 atttatctag catcttttct ctccttaatt aatatttatt tttattatca ttaaaatttt
    14941 tataaaatta actttcttct aacctaacaa cactgcaact actatttact caacaactct
    15001 tgaacttgtt ttaataactt tggtcctcct aatggactat aagcttgtgc ttgtattaat
    15061 gcacatggta cactagcctc atcagcaaaa gcttttaaat agtcaaatct atgtctgact
    15121 tgtggagcta ccatagcaat atcccatcca tttttaactt cattctcaaa ctcttgagta
    15181 ccaacagcca aaacatctat atctattcca ttttttgctc cttctttttg taatgcatta
    15241 actgctatag cacttgacat ccctgatgaa caaacaaata atactctcat attgattccc
    15301 cctgtttttt tatttctttt caatcattat agcatgtatt tttgattaca ggaatacgtt
    15361 tgtatatatt ttttcatatt ttacattttt aattgtaatt ttatttcatg catttatatc
    15421 ttgctttaat tgctttattt atctaatcat tcttttgtct aaaattacac actacttaaa
    15481 atactcatat cttttcttaa aaaagaaaaa agactatctt ttattaacat aaaatagtct
    15541 caatactttt ttaaatatgt attcctttat atatccagaa gtaacctatt attgcaaatg
    15601 ataaaacaaa taaaatatac agtctaaaaa atcccaaaga aaaacctctc ttagtttcaa
    15661 caaagtatct tgtatatgca actgcaaaag atgtaattaa tgaatttcct ataacaactc
    15721 caaatctatt atctattcca aatatagata ataacaaagg aaaaactaca gtacttacta
    15781 gagatgaaac tattagtatt aatccacttt taaaacttat agttggaata ttataatctg
    15841 ttctttgatt tttctccatt tctttcttag tatttttatt actttttgca tttttataat
    15901 tattattttt ctttcttttc ttttttttat tattagacat gtcatttacc tccaaaaggt
    15961 ttaggtgtta tattccctaa aataacttta tttttagccc ctgttgcaga tattacatta
    16021 gaaaaagaat tatttaatgt ttcattgccc aagattacaa atgccaaagc ctcctttgca
    16081 tcagaagaat acccatattc atcttgagtt aatacttcaa cctctaataa taactctttt
    16141 atatatccta ttaaagttag attatgaact cctccacctc caattaataa agtatctaca
    16201 ttaacctttg gaagtatgaa gtttttataa ttataatata tagcttttgc cgtaaacata
    16261 gttactgttg ctatcaaatc atatttatct acatgtttat atttgttaag catgttatcc
    16321 aaatagactt gtccaaatac ctctcttcca gtgcttttag gtggcgcttg actaagatac
    16381 ttatgactca tcaaatcttt taacatttct tcattaattt taccttttga tgcaaagtat
    16441 ccatttttat catactttct attaaataat ctttgacata ctccatctat tatcatattt
    16501 cctggtcctg tatcaaatgc aaatacatca tctatgttac atgatttagg tattatagta
    16561 atatttccta ttccaccaat attttgaagt gctaaatttt tatttttatc actatataat
    16621 aaaaattcac tatatggtac taatggagca ccttctccac ctgctgctat atccattact
    16681 ctaaaattag atattacctt tgtatttgtt tcatatgcta taattgctgg ttcacctatt
    16741 tgaagcgttg aagatacaaa attattataa cttcttggta tatgaaagat tgtttgacca
    16801 tgagatgcga taaaatccaa atttgctata tgaaagtttg ctttatgaca cactgatttt
    16861 acagctttac taaataaata tccaagctta aaatttaagc tacagattaa atcaacactc
    16921 gattcctctt ctatacagca ctttcttatt tcgtctttta tatctttagg aatttctaga
    16981 gttataaatt ctatttgctt aactttagta tttctaccat tcccactaat ttcagctagt
    17041 actgcatcaa ctccatctaa ggaagttcct gacattaaac ctacactata catagttatc
    17101 atccttttaa gtttatagtt attcctcccc aaatcaaggt attaagttta ataattttag
    17161 aattaatctt atttcatctt taattgcgat aatttactct tacgaaatta atcgagttaa
    17221 tcttatacac gttttttacc ttagctaaat cttacattaa tttattttca gtgtcaatgt
    17281 aatgcatgta attttttttc acaaacaaaa catattctct ctccaaaaac catattaaaa
    17341 tagttactac aaataaaaaa cataccaggt acctatctga tatgtttttc atatataata
    17401 attattattt tataatatag atagaacatc atttaaggca ctaattaaat cttcactatt
    17461 ttcaagaact aaatttattc ttattgtata tgtcgatttg tatatgatga tagattttat
    17521 agtctaataa cctaactatc taggcttaaa taatccgata tatcataaaa gtagatatta
    17581 aaaattgtat atgaaccaat tttcgaacat acctcaatct catgccctaa actatctatc
    17641 attttcttta caaaatacat ccccattcca gtagacttat acaattgatt tcttccattt
    17701 ttccccgtaa atcccttgtc aaaaacccta gatatatctt cctcatttat acctatacca
    17761 aaatctttta tagataatac cactccattt tctaactttt ttgaattaaa ttcaatctta
    17821 ccaacttcct ttgaatactt tatagcatta ttaataattt ggtctaaaac atatgacatg
    17881 catttagaat ctgtgtaaac atcattttct aattcattca aactaacttc tacattattt
    17941 tttataagca aaaatgaatt attttttata gacattttta ccaatttttc taaattaaat
    18001 ttatttataa atacatcttc aaacatagtg ttgcttctac tactatacaa aatagagttt
    18061 actaaaaaat ttatctttgc aacctgattc ttaatatcca aactatcttc tatgctactt
    18121 aacctatctg taattatact taaagaagat attggaattt ttatttcatg aacccattta
    18181 gctatgtaat catctaattc ttttaatgat tgtttataag tctctatgtc actattattt
    18241 tttattttta agttttctat aatatctttt attagatttt cttcaaaaga ttgtccatca
    18301 attaaataac tgtctatttc accactattt tctatacaat tatataaatt tatataacta
    18361 tttctaaaat ttatataatc tataacaaaa aataccatta ttataaacag cactaaaaaa
    18421 tctaagtata ttaattctga atatctattt tttaaaatat ctatagcaaa taaatagata
    18481 tttattatac taactacaac taaaggtaga gcaatatact tagacctacc ttttaaatat
    18541 tttactagca ttatattata tatcctatcc ccttcttagt ttttataaaa tcatcaaaac
    18601 ctagttcttt aactttactt ctcaatctat tcatatttac agtaagtgca ttgtctgtca
    18661 caaactcatc attatcccat agagtcatca taagactttc ccttgataca accctattct
    18721 tattttttaa taataatgtt aaaattttta tttcgttttt agtcaactct atacttttat
    18781 ccttatactt atgttttata atccctttcc ccacatcaaa catcaaatct tcacaataca
    18841 aaatactatt agaatcacta taattataga ctcttcttat tataccattt attttggtaa
    18901 ccaatatgtc tatagaaaat ggtttggtaa tataatcatc tgctccatta tttataccca
    18961 ttattaaatc catatcagaa tctcttgatg ataaaaatat taatggtaca tttgaaatag
    19021 ctcttatttt ttcgcaccag taaaatccat tatataatgg taaatttaca tctaaaagta
    19081 ctacatctgg ttttttatcc ataaattcat ctaatactac ctcaaaatca tcaattaatt
    19141 ctactttaaa tccccatttt tcaagtgcta acgcaatctc ttttgataaa tcaatatcgt
    19201 cctctactaa taaaattcta tacatttgta tattctccat tatcctaata tttcactatg
    19261 ccatgaatta ttaatatcat aacatatttt atataaattt attacccaaa ttatttagtt
    19321 aatcaacaag gagactctta ttacaagaat ctcctttctc tttattaata tatcaactaa
    19381 tttttataca ctacactctt aaacttatta acagatactg ctccatatat tacgaatatt
    19441 atcaaacata tcactaaact tagtatatat ataccagata aatcgttcat caataaatct
    19501 cctgctaatc tcaatgcaaa ataactagat atagttgcac ttaacattgg caaagtataa
    19561 aatatagcta cttctttaag tatagctcta tttatatctt tttctgtagt acctattttt
    19621 aataaaatct tgtatttctc tttatcttca tatgcatcac tatatatttt catatatatt
    19681 atacttccag ctacaattgc aaagactaag aataaaaaca caagcactac atatgcaaac
    19741 ttcatccatt gactctcacc ttgagcttta tatccattct gaatatatcc attttttaaa
    19801 cttaaattct tttcaatatt gttgaacatt acttggctat tttcttcttg aaataccttt
    19861 gcaccataaa aatatacttg ttgaccctta tctcttagtt taaaatatgt atcatcattt
    19921 accactataa tactttgatt aagtcctgtc cctaatactg gaacttttac ttctcccctt
    19981 gaaatattat ataactgacc atcaagtttt gtcttgactt cttttgtagc tattgatgct
    20041 atcgtttgag gactttttag ctctattaca ttatttccac taactaatct ttcaccatac
    20101 tcttttaatt ctttatcatt gccattcact ttaagagtat tacaaaaatc actatatttc
    20161 attatagtat ctgttgtatc ataagcttct tttatatctg ttttctttaa gattgttagt
    20221 tctggattta cggagtactt tatcttatta gtatctttta ttatgttctc tatttgtttt
    20281 ttattcactt catctttatc cattgaaact atgctaatag tgtacacatt tctttgttct
    20341 tgggcattct tatgtatatg cttcatagca actgaagcac caagagttga tattgttgta
    20401 gttataatta tagctattat agcataagtt ttatagtttt tatttaatcg gtagtttata
    20461 ttgtttatcg caattatatt atttccatta aataatattt ttttattttt gattataata
    20521 tcaaatataa caggcataac tgatttgaat aagccataag tacctactat tattatacct
    20581 ataacaggta gtacactagt tatatctcca gttcttatat tcgtagaaag atagtatcca
    20641 tatcctatta ctataagtga tactatagct aatatatata tacctattcc tacctttggt
    20701 attttttctt gttttttaga tatattgatt agatttatta cactacttct acatattgtt
    20761 ataaaacctt ttacagccat tattataaat atagaaataa agattaaagt agcatatagt
    20821 atagcttcta tgctaagtcc attagatacc tttatattaa atccagataa ttttattatc
    20881 actacttgaa aaaatctaga tgttattatc cctataatta ttcctgttat acaagaactt
    20941 attcctataa gcatattttc tacaaaatat atttttccta tagtatataa atctaatccc
    21001 ataaaggaca atattccaat ttctttagac ctattcttaa aaaatatatt tgttgcatac
    21061 catataaaga aaaataaaaa tactgatagt atcattatta cagctactaa cactgatagt
    21121 gtaaattttt tattttcctc ttgtaacaca tttatagcat ctccatatct taataattca
    21181 aaattagtca gcacaactac tgaaaaaacc atagatataa aaaatgctag ataagttctt
    21241 atgttactct taaaattatt ataagcaatt ccaagtatac tcacttacat ctcacctccc
    21301 atagaggcta gcatatccat aatttttcca taaaattctt ttctactatt tcctttgttt
    21361 aatttacact ttatatttcc atcatttatc atatatactt catttgaata acttgccgtt
    21421 agagggtcat gtgtaatcat tataatagta gcgttgtttt ctctgtttat tttttctaat
    21481 gattctaaaa gttcatatgc tgatttagag tccaaagcac ctgttggttc atcagcaaat
    21541 atgactgctg gatttgtaat taatgaccta gctgctgcgc ctctttgttt ttgtcctcct
    21601 gataactgat atggatattt atctaaatga ttttctaatc caaatttttt agctatagaa
    21661 aataccttag cttctatctc cttgcttttc ttttttccta atgctagagg aagtgctata
    21721 ttgtccatta gtttcatatt gtctaataga ttatagtctt gaaatataaa ccctattttt
    21781 tctcttctta attttgatag ttcattattt tttacttttg atatattaat tccatctagt
    21841 attatttctc ctgaagtttg tttgtcaagt gtagacatta aatttagcaa tgttgtcttt
    21901 cctgcaccag atggacccat tattgctata aaatcacctt cattgactgt aagagatata
    21961 ttttttaaca catttgtttt aaatcctttt attccataat cttttgatat attttttatt
    22021 tttaatattt ctttcataat aatagcctcc agttgctaat tttttaatat atatttattt
    22081 taaaggtttt atataaataa atccttaagt aaatattaca ttttaactgt tagcattaca
    22141 cttttgtaac atatggaaga ctattataat tatagtggaa atatcttaaa ataaaagcat
    22201 gattcacttt tttgtataaa caaagaaaag aagcccctaa gaagcctcta atctatacaa
    22261 taattcttct ctataaaaaa ccaaaaatac aaccttgatt gtggcaaata caggtactat
    22321 aaacaagtga tattactact atatattaaa acaattattc ttgaagataa ttcaataaga
    22381 ctatcaagcc ataagctaag catccaaaaa gacttaatat cattaatgta taattatacc
    22441 caatattaat actcaaaaaa ccagcaacag ttggaataat cagagatgaa cctcccataa
    22501 atatacttaa agctattaat tggctactac ttctaagttt tttaggagaa acttcaaata
    22561 ttaatctttt tgaagtaatt aaaattaaag gagtagaaaa cacttgaaaa acacacagta
    22621 taataatgat atttgaatca tttgttaaag caaataatag aaactgaact gttatcataa
    22681 tagcacttaa ttttaataag tttaaactgc tatatttttt taataaataa gaaccagcca
    22741 gatatgttgg tttctctaat aatgactgta aagaccactt taaagatatc tgagaatttg
    22801 tagcatttaa agctatcatt ttatctatta cagtacagtt atttgctacc accattgagt
    22861 ataataagaa taaaatacat actagtaaga tatatttttt atcttttaat aattcaataa
    22921 tatctttatt agttacattt attttcttat taatcttttc aatatcaggt aataatagta
    22981 tatttataat aagtaatact acaattaaac caatcgctac agataatcca aaatatgaga
    23041 atctaagaat caagtaagat gctaccatac ttccaatagc ccatccaatc gacccaaaag
    23101 tcttaataaa tgacaaataa ttattaatat tatctccaca acctattatc catgtatcat
    23161 ataaactaca gcaagtattt aataatcctc ctgataaagc aacaagtaat aagtatatta
    23221 taaaagttgc agattcagta gaaaacataa taactgatgc aattccataa actgataaac
    23281 taattaaaac aatttttttc attgtttgat acttatcagc taatactcca aataataatt
    23341 gaaataatat attggttatt gcatagctcg ataatataat tcctctttca aacgctgagt
    23401 aacctaattt tgataagaaa ggtgtgaatt ttgttgaagc aaaggcaaaa ataatatatg
    23461 agaaaaaata gaatatgata aatttaaatt taatcgcttt attaatcata atcaatcaaa
    23521 attgataact ttaataccac tatttccttc ctgatttaag tttgaaagat gatattttac
    23581 cgtattagga ttctctacaa taactaaagg aatatataaa gtattttcaa gtaacttatt
    23641 atcaatttct actaactttt cccccatatt aacttcttga ccttgtttaa cttctaattt
    23701 aaagttttct ttttttgttg ttgcactatc caatccaata tgaataagaa tttgaacatc
    23761 attttgcaat ttaattccta tagcatggtt agtttgagca ataaaactta ttactccttt
    23821 agtcggtgat ttaagaatat tgtcctttgc tatcatagca aatccatctc ccattacctt
    23881 agttgaaaat actttatcag gaatttctcc aagattaatt atttttccat caatgtatga
    23941 attaattgta cttgcttctt tttttctttt aaagaacatt atagacactc ctctacataa
    24001 ttaactttat tctaattatc attacaaata acgatattaa gcatactgca attgaggaaa
    24061 aaagagcctt atagctcttt ccccattgta gttctttaat actgcttatg atttgtttaa
    24121 ttccaacaaa tttataaata taggtaaaca tgataacaat agttattgtg taaatttgga
    24181 atatctgccc taataagact aaatagaaag caatcatgtt ttcttttatc tctttattct
    24241 tttttatatt gtaaataaca tatgcactgt atactgcact aaagttagag attaaattta
    24301 aacttgcatt aacatcattg tttaaaagtt gtgaaaatga aatgtttgta aataatgatg
    24361 tcaattctaa atacactata tataaaacag gtaatattag aaaacaaacc ataaccactg
    24421 aaagaaatat attttcatct tttaatactg ctgttatatt ttttatttta tttgttatca
    24481 tgtttttgtt ctccttattt aaaagttggc cagaaatcct tattagccac aatcatttca
    24541 tctaagattt cttttgctac ttttgcactt ggaacagttt tactcatagt aaacgactgc
    24601 cataattttt gataactttt ttctatccat gcttctacag ctaatttttc agaagcaact
    24661 tgttgttcca ttaaaccttt ttggaaagtt ggaattttac ctatagacat aggttcaacc
    24721 atatcttttc caacaaggca aggaatttca atcattgcat catctgcaaa attttcaata
    24781 gctccattat taggaacaat cagtaaaaat ctttcctgag tattaaatgc taatgcacaa
    24841 gctaattcaa caataaattg agaatgttca cttgcatcaa accatgtatc ccttgctgtg
    24901 ccatttttta taattctttc acattcttcg aatgtatcct tttctcttct atccataatt
    24961 tcatttgctc ttgtataatt tggattagca tgttcaacag tttcatcagc cattaaataa
    25021 tattttaaat aagtattagg taatgtagtc ggttctattt ctaataagtc ctttgctgct
    25081 ctcatagttt ctaaccaact agattctttg tgttgacctt gaggtgtaaa ttcctcatat
    25141 ccttttttag cacaatattc ctgtaattta ggcattaaat catttccttc tttgtcctta
    25201 atacttgtcc accacccgaa atgattcaat ccataatatc taacatcaaa gtctttacga
    25261 gaatttaaac ctaaaattct agcaaatatt tcctctaaac atactggcat atcacaaata
    25321 ttaataattc ttgaatttgg tcttaataca cgacatgctt ctgcaactat agctgctgga
    25381 tttgaataat taagcatcca agcatttgga gaatattttt ccatataatc aatcatttcg
    25441 attattggac ctattgttct taatccatag gcaattccac ctgccccaca agtttcttga
    25501 ccaacaaccc catattttaa tggaattttt tcatcttgtt cacgtaaagc atataaacca
    25561 acacgaattt gtgccattac aaaatcaata tcagtaaatg cttcttctgg atttgttgta
    25621 taactaaatt taatttctgg atttttctct ctaacaatta ttgcacatgc ttcagcaact
    25681 tttctttgtc tctcatcatt attatcatat aatttaattg attcaatagg aaatttagca
    25741 acactttcaa ttaacattgt tacaattcca gcagtataag tactaccccc accagcaatt
    25801 agtatcctct gtctttttct ttccatcttt ccttctcctt tataataaat tttcaaattc
    25861 ttctcttaca cttggtactg aaagcccaat aataatctga atagcttttc cattatgcac
    25921 taaaccatgt gcacctacta ccttaaaatc ttcttcttta gaaataattg agtcatcctt
    25981 caaggttaat ctcaacctcg tagcacagtt tgtaacatct acaacatttt ctgctccacc
    26041 aactaatttt atgtattcag atgcttgttg agaggcttta ctcaatttat ttcctttttc
    26101 atctttagtt tctaagtatt catttttagt atatagtttt gtttcttcat tatcttcctc
    26161 tctaccagga gttttcatat caaacttctt aattaagaaa gtaaataaaa agaaccagat
    26221 aaatgaaaat ataatcccta caacaacttg aacaacatat accttccagt gatacattcc
    26281 aagaggaagc caatttaata caacccagtt aataattcct ccaccaaaat caccaacaac
    26341 tcctaaggca aacgaaatcg tttgcaagca tgcatctaaa aatgcatgta ctaggaataa
    26401 aagtggtgct acaaataaaa atgtaaattc taacggctca gtaattccag ttaatactgc
    26461 agtaagagta gcaggaatca ttaaacctaa tacttttttc tttttttctg gctttgcagt
    26521 tacatagaaa gcaccaaata cacctaatga accaaacacc ttcgataatc cagataatga
    26581 aaatccgatt ggatacattt cctttagagt cttagctgaa gtttgaaagt cctgaatatg
    26641 agtagcccaa tatactgatg taccacctgg aacaacaaca ctatcataac aaattggtgc
    26701 atatacaaaa tgatgtaatc cagttggtat taaaatcttt tgtaagaatg cataacacca
    26761 aactcctata tttccactat ttataaaaaa cgtttgcaaa tgtctaataa cattttgaat
    26821 atgaggccaa ataaaacaag ttaataatgc aactggtatc ataacaaaga aacaaattgc
    26881 aactacaagt gatgagcctc taaataatcc aataaaatct ggtagttctt tatcataaaa
    26941 tctattatga atataaatga caatacctga tattaacaaa gcaccaacca taccagtatc
    27001 taatgtttta ataccagcaa tgcttacaag tccacttcca gcacttattt cagctgcgaa
    27061 atcaactcca aagctttttc cccaaaaact taacatagaa cctacaaaat aattaaaagt
    27121 caaatacgtt gctaaagcct ccatacaagc tcttgcttgt tgcttttttg caagtgctat
    27181 tggtaaagaa atagcaaata ataatggtaa ttgattaaat accatccaag ctccactaga
    27241 tattacaccc caaaattggt accaaatatt ttctggtgta gcaagtgaac ccataattga
    27301 ctgattttga aatacaattg agaatccaac cattatcccg gcaaaagcaa ataatagtgt
    27361 tggtgtaaac attgcccctc caaaacgctg tattttcttc atcatataaa ttactcccct
    27421 cctcatattt ttagtttatc tttggcctta gatatctatt attttaacag gttaataaat
    27481 atatacaatc tttagggtac atttggagct tattcacagt caaataagtt tttgcacatt
    27541 tttatgttca aattctcata aaaaaaagaa tgactacaat ttgcaatcaa tcccttctgt
    27601 aatcattcta tgccttttat aaatactata tttaataaat aataactcaa tcaatataaa
    27661 atataacatt gtcaatttat aactagggtg catttgtaaa aatgagatat tagtcgctga
    27721 aatataaatt gattcatcac ttaaatcagt caatgtatta tttttaaact ctgtaattga
    27781 aattatttta gttcctatta attttaatct tctagcaata ttaagtgtat tctcattctc
    27841 accacttagg gatataataa tcataacatc atttttactg acaatattgt aaaaagaatc
    27901 atcaaatgtt cttccctcaa aatcatatat tatttcttga catgataaga acattctctt
    27961 tatctgtttt gcaaccacat tttgaatatc acctgaacca taagcgtata ttgttcttga
    28021 ttcataaaga agtttacaca atgcatcata atctttattt ttttgatctt caacatactt
    28081 aattattgaa ttacatgcaa tatcaaatga ctgattttct atgacatgaa ccttttctga
    28141 ttcccagctt aataatactt taaactcact gaaacctttt aaatctaatt ttttaacaaa
    28201 tcttgtaata gttgcacgag acacattaca tttcatagca agttcattta ttgacatctt
    28261 actacaatgt tttttatttg cagttatata tttccatatt aataaatctg tatcattcaa
    28321 tttattataa tttaaaaaaa tcatttcttc taatctcata aactattatc ccctttaatt
    28381 aaaaatcgtc ataaatatta taccaatatt caacattaaa ttacagcgta ttcttatatt
    28441 tactatttag cccataaaat tgactataaa aaatactgct ataattgatg tttaaaaaaa
    28501 tgtagtttta attttattct tttatctaat aattaatatt ttcaagttct agtgcttttc
    28561 ttatgcaatt atcatcttta aaatcagcag tccttttaca atcttttact ttaaattctg
    28621 gaatagtttt aaattcctca tcacatattc cattcttatt taaatacata caacttgcca
    28681 ttctaactat tagaccacta ttttttaaat taaacaatac agggtctata caccctccat
    28741 ctccgccagt agtttcacca actaaagtcg caaatttagt ttctttacaa aacattgcaa
    28801 atgactctga tgatgaatat atttttctat caacaagtaa gtatatatta cccttaaatt
    28861 ttgaatcatc tgtagatttt atagtatagg aagtatcttc aaaatcatta aaatctttta
    28921 taatttcttt aggtgcattt tcctttacac ttgctggtaa attttctaca ggatttaatt
    28981 ttatatttct tgcatttgta tattttttta ctatttcatt attatttcta taaattctat
    29041 aaccatttat tttgacatca ttttttatga gtttagatac gattccctgc caatacctat
    29101 cacttccacc taaattacct cttatatcaa taattaaagc tttatgtttt tctaaagtgt
    29161 taatataatc tccaattatt tttaaatcat tatttataga gccattcttt gatgacattg
    29221 atggtaaata catatatcca atctgaccct taataacatc ctttaaaatt aattcttttt
    29281 ttacaaaaat atcatctggc atttttattt taagattcat agagtcatat ctatccacaa
    29341 cttttttatc attaagaaaa tcataccaat cattattaga gtatgatttc ttaaaaagtt
    29401 catatctttt cttattatct attacttctg tgtgtttatt atttaaatca gataatatag
    29461 atgacagttc ttctataaat tcttcatcat tttcagtgtt ttttattcgt tttgtatatt
    29521 catccttatt tgctaaccaa tcaatattat taagtctctt atttacacct agatatggat
    29581 atcctgtctt tacaacatta tacacataat taaagtcatc caccttttcc tcttcagaca
    29641 actgattctt ttgagaataa gtagaattac ctaataagat tataaatgct aaaataatta
    29701 ctaaaaataa tactttcttt ttcatgtaat tctcatccac tttcagattt tatattttaa
    29761 tacattgtat cattatttta ttatcaccta aacagttaaa agaaattctt gaagatatat
    29821 tccactatta ttctatttaa aaatttttat ttgtattttc aaaattattt catgaaagtt
    29881 ataaaataac aattatattc aaatatctat tttactgcta tatcctgaaa gtaaattctt
    29941 atcagtgata tactaaaaaa gatatgctaa aaaatttatc cattataatg acttaaattt
    30001 agatacttta ctgattttta tttattagtt gagaaaggta ttgataatta aaaatattga
    30061 taactataga aatgattatt ttttatagaa attttaagga tataaactaa ttatacttaa
    30121 gtctatatcc ttaatttatc atgattatga gaatttttac aaatacttat ctttgtccgt
    30181 tttagaataa aaacaagaac atatcctgtt attttattca aacatccaag tttaattact
    30241 acacaattac ttattagaaa ttgtatctac ttcatatata tatctgttaa gtatagcttc
    30301 tagcatttct tgtcttccag acttattctt tataactggc atttgcagtg cataagattc
    30361 taactcttta aatccaacct taccttctac tatatcctta cctatacctt cactaaaact
    30421 tgcatatctt tctttagtaa agttttcaaa tacctcatct tctaataatt tatgagctat
    30481 taataatccc tttgcaaatg tatccattcc tgcaatataa gctaggaata agtcttctac
    30541 ctcaaaagat gctcttctta ctttagagtc aaagttaaat cctcctggtg ctattccacc
    30601 ttgctttaac acttcataca tagcaagtgt tgcatcatat atatttgttg gaaattggtc
    30661 tgtatcccaa cctaataata ggtctccttg atttgcatct atactaccta aaacattgtt
    30721 tattcttgct atatttaatt catgttggaa agtatgtcct gcaagtgttg catggtttgc
    30781 ttctatattc attttgaagt atttatccag attatacttt cttaaaaatc ctaaaacagt
    30841 agcagtatca aaatcgtatt gatgtttagt aggctctttt ggcttaggct ctattaagaa
    30901 ttggccagtg aatcctattt ccttagcata atctacagcc atttgtaaga atcttgcaaa
    30961 gttatccatt tcaagttctg tattagtgtt aagtaaagtt tcataacctt ctcttccacc
    31021 ccagaataca aaattttctc ctcctaagta cttagttatt tccatagctt ttttaacctg
    31081 agctgctgca tatgcatata catctgcatt acatgttgta gatgcaccat gaacaaatct
    31141 tggatttcca aacatattgg cagttcccca taataacttt atacctgtct tttccatatt
    31201 aacttttata tactcaacta tttcatctaa tatcttattt gtctcttcta aatctcttcc
    31261 ttctggagct atatctctgt catgaaaaca gaaatactca attcccatct tagacataaa
    31321 ttcaaatcct gcatcaactt taatctttgc tatctcaatt gggtctgtta cattattcca
    31381 aggtctctct actgtgccta ctccaaatgg gtcattaccc tctccacata aagtatgcca
    31441 atagctcatt gcaaatctta agtgttcttt catagtctta ttacctacca cttgttcagg
    31501 attgtagtat ctaaatgcta attcattgtc agattttact ccttcaaatt ttatctgtcc
    31561 tattccttta aatatttcac tcatttcatg tcctcctaat attttacaca tataatatat
    31621 gtcgtatgtt ttcttaattt aaaactattt tctatcttta tttttctttt taagctaatt
    31681 taattattta tttttgtatt aactacttca tctaataact taaagtcatc tttcaaagat
    31741 ttgtatattc ttttatacaa tctatgatat atcttgtatg tatctacatt ttcacttatt
    31801 ggttctaatt tagttgaagt ttttattata gcatcacaag ctttttgtat attttcatat
    31861 attccagctc ctactaatgc aagaattgca actccaagtg ctggtccttc acttgaattt
    31921 atagtatata catcttgatt aaacatatct gcttgcatct gtctccatac tttacttttt
    31981 ccacctccac ctgaggctct tacttcatta acgtctatat taagattctc tattatatcc
    32041 atacagtctt taagactata tgaaacacct tccattattg accttgcgat ttctttttta
    32101 gaatggattg gagataatcc aaagaacaca cctcttgcat aagggtcaag atgaggagtt
    32161 ctttctccca tcatatatgg taagtaaagc aatccattac atcctgttgg tacttgactt
    32221 acttgattat ttataatctc atatacatct tcacctaaag aatttgaaac ttccacttca
    32281 ctttgacaga aattatcttt aaaccatttt aatgacaatc cagctccttg agtaactccc
    32341 ataacatgcc atgtatttgg tattgcatga cagaaagtat gaactctacc ttctttatca
    32401 atttttggct ctttcgtata agcaaatact acacctgatg tacctatagt agatgaaact
    32461 actccatctt taactattcc atttcctata gctcctgctg cttggtctcc agctcctcct
    32521 accactattg ttccttcttt aagccctgtc aaacttgcta catctctagt cacataacct
    32581 gtaatctctt gtgattcata aactttacct aaaagatttt tatctatatt taacttttct
    32641 agtacttcat cgctccaatc tctttttctt atatcgagca actgcatacc acttgcatct
    32701 gatacctctg tagcatattc acctgtcaat ttgtatctta tataatcttt tggaagaagt
    32761 attttattag tatttatata tatatctggt tcattgtttc taacccataa tatctttgat
    32821 gctgtaaatc ctgtaagcgc tggattagca gttatttcaa tcagtctttc ttcacctact
    32881 aaatcagtta tctcctcaca ctcttttact gttcgttggt cacaccatat tatagagttt
    32941 ctcaatgttt taccttcatt gtccagcata actagaccat gcatctgccc tgataatcca
    33001 attcctttta tacattcact gcttatattt gaactttgaa ctacttctct tatagattcg
    33061 actacagctt tccaccaatc atttgcatcc tgctctgccc aacctgattt ctcttgtata
    33121 agaggatatt catatgtaca actttttata atatttccta gtttatcaaa taaaactgtt
    33181 ttagtacctg atgtaccaat atccacacct aatacatact ccaacttcat ccctccttga
    33241 atgccacttc ataactatcg ttttcctatc ctaatttttt tatattttag gtatatttta
    33301 cttgctttat ttttgttagt atattaaact aacttatgaa ctaataataa aatatttaat
    33361 tatctttgtc aatgcaaaat aaccttttat ttttgtgtaa aaagtattac aatattattt
    33421 taaggaggaa tatcaaattg gttactgata aatacactat tcgagaaatg aatgaaagat
    33481 tggtacttga acaaattata aaaaatggtc ctatttctag ggcaagtata gcttctacta
    33541 taggattgaa taaagcaact atatccgcta ttaccaaaaa acttattgat gaatctctag
    33601 ttcatgaaat aggaattgga aatagtactc atagtggcgg aagaaaaccc atattattag
    33661 tatttaataa atgtgcaggg atttctttaa gtatggacat tggatacgac tatatatttt
    33721 cttctctatc ttacttagat ggaactatta taaattctaa gaaattaaca gatatacaag
    33781 taagtaaaga caatgttata caattgatag atgaaattat aaatagttat aacatatcca
    33841 aaatagacac tccttataag gtaattggtc ttactttggc tatacatggg attacttgtg
    33901 aaaataaagt attgtttact ccatattata atcttaatga gattgactta tatagcatcc
    33961 ttagcaaaaa gtatgacttt cctattcata tagaaaatga agcaaactta acagctttag
    34021 ctgagaatac tttttcaact gtacataact cactacttag tctcagtatt cacagtggat
    34081 ttggttcagg cattataata aataataaat tatatagcgg cagaaatggt atgagtggag
    34141 aaattggtca cactatcatc atgcctaatg gtaaactatg tccttgtgga aatcgtggct
    34201 gtttagaaca gtattgttca gaaaaaaagg tatttgaaca gctttcttct ttagaaaata
    34261 ttcctaaaat agattctgat atagtaaagc aactatatta tgaagataac cagaatgcca
    34321 aaaaagttat tcatgagttt tgtagttact taacaatagc tataaataat gctattacaa
    34381 cttatgctcc tgaaataata tatttaaata gccaaataat tagtgatatc cctgagatat
    34441 tacagattac aaaagatatg ttagttagct cttttaacaa aggaataaat atagaaattt
    34501 catcattagg gtctgaggca tctctatatg gtggctctgc cgtaaatatc aagagctttt
    34561 tgaatataca aaatttaact ttaattaatg aaatataagg gttatgacta tatacagcca
    34621 taacccttta aattatacat tctaaaatta gatttattat atagtttatg caagattagc
    34681 tatatttttt aaaaattgta tatcaattaa gtattaacac aagtattttg ttttaaatat
    34741 taatataatc ttcctactca tcatcagata ataaacttgc attttgttca accatagaaa
    34801 tattatcttt acctattttc tctaattttg ctgccaattc ctttgtatct aaaaaagctg
    34861 attcaataac catacctaaa tttagccctg aaataatttt aattcgactg tcatcattgg
    34921 ctactaataa agcagcattg catggagttc cacctagtaa atctgccatt ataattattt
    34981 ctgaactttc cttgtacact tctaaagctt tttttaattt ttctattgtt ccttctattc
    35041 catcatcttg tttcatattt acagtaggat aatctataga atcccctatt atcatttttg
    35101 cagaatttaa gacttcttca gccatattgc catgactcat caaaataata ctattcactt
    35161 taatacacct ctttaaatct ataagatgtc tacaagataa gttttcttat catcaggcgt
    35221 cattatagtt gtaatttcaa ttccttcatc taaaagtctt ttaaatgctt ctttctcttc
    35281 ttcagtaaca ctgatattag gtcttagaac tgttgtatct tttctacttg acatatttcc
    35341 tacatttata ttatgtattt taaatcctgc ctctacaaat ggaataaggt ccacaggaga
    35401 cttaacaatt aataatacat tttgtccttc atactttcct gcagtaatat tttttatagc
    35461 agtctcttct gtaattatag atgacgctat acctgcaggt gtagccattc ttaaaacttg
    35521 tttttgaaca gaattgttag ctactgcatc atttactacc attaatcttg taacacccaa
    35581 tttattactc cacatagttg caacttgacc atggattaaa cggtcatcta tacgaatatt
    35641 tttaatacct ttcatttcca tatctaatat catcctttcc ttattttaaa atacctaatg
    35701 catataaaat tattgaaaca accattactc ctaaaattaa gtatataggt tttatattct
    35761 ttttaagagc ccaataaaca atcacaacta aaattgcagg aactaaccca ggcataattt
    35821 ggtctaatat ttcttgacct ttcattgtaa aatcaccttg ttgaaagttc aaagcaacat
    35881 tagcttttac aactgaaggt attaatgcac ctacaaccat taaacctaaa atagatgtac
    35941 tctcagttaa aatctttaaa cttttttcaa ttgaagatat tagcttagta cctgatgtat
    36001 agccagcatt aaatagtggt atacttaata atttcaatgc tacactcact acaatccaca
    36061 gtaagattcc aaatggactt ccatctatcg ccatattagc tgctatagct ccaaaaattg
    36121 tccacggaat aacgacaaat aaactatctc ctaaacctgc tactggtccc atcaagcctg
    36181 ttttaattga agcaacagcc tcttcagtct cttcacttga taactcctcc attgctacat
    36241 taatacccaa aatataaggg gcaacccaag gattagtgtt aaaaaattgt aaatgattta
    36301 atacagcact ttgtaacttt tctggattat ctttgtatac tacttttaaa aaaggtagta
    36361 ctgcataaca gtatgccaag gcctgcatct tctcataatt tgaagaaaca gaactagtaa
    36421 aaaaccagcg ccataagaca ctttttttca ccttttcatt tgatttattt aatgatacct
    36481 tatcactcat cttcgtccat acctcctact acagtatatt gttgttcttg attttccaaa
    36541 ttctttttgt aaattataag tgcaattgct ccaccaatta aagctacacc taataatggt
    36601 actttcatat atactgctaa aacaaaacca attactaagt aactaaaata ctccttagca
    36661 ggaagatatc taagtaataa tcctatccct actgctggaa gtagtcctcc agctactgtt
    36721 aaaccacctg ttaaccattc aggtgtatat ttcaaaatgg tattaattaa agaaggtcca
    36781 aatattacag atagagcaac tggaatacct gttgtagctg ctgttaatag tactcctaac
    36841 atttgcatat aggttatatt tttataattt ccttttttag ctccatcttc tgctttatga
    36901 actagccata taccaatagt atttctaaga acatctaatt gtaccatcaa taaagcaact
    36961 ggaataccta tagagattcc tacagatgct tcttgcttag tcgtaatagt tataaatgtg
    37021 gctactatac ttgctgtttg ataatcaggt attgatgctc caccaaagtt actaatacct
    37081 aatgataata gctgtaatgt acctccaata tataaccctg tatttatatc tcctaagata
    37141 agaccagtaa taaaacctgc tgttactggt tgatatgttc caaacattgt tgaatttttt
    37201 tcatagttta taaaaaatcc atatagtacg attaataata attgccataa ttgtggctcc
    37261 attatgattt cacctctccc aaaatatttt ttagttcttt aaaattataa ctggaatctt
    37321 gctttaggaa aataggaatt tcttccagcg ggcattcaac ttcataagtt ttcccacctt
    37381 cataactaac tccactaaat atattttccc atgtatgtcc ttttggtaaa tatacttttc
    37441 tacttctatc tttataattc attattggag ctaccaaaat ttcatctcca agcatatatg
    37501 tattatccac ctcccaagtt ttatcatctt caggaaattc ataaaataaa gttctcataa
    37561 ctggtgttcc atcttcatgc gcttctttca tcagtttttt taaataagtt tttaagctct
    37621 ctctaatttt tatgaatttt gtaagaatta cttcaacttc ttcaccataa gaccatattt
    37681 cattaggagc tccagttacc attgagcctc cacctttatt tgataatggt ttactatgag
    37741 gcaatctatc tccatgcatt ctcaaaattg gtgaaaaagt agcatattgg aaccatctta
    37801 ccataagttc tctaaattct gggtctttag gatttcctcc atggaaacct ccaatatcag
    37861 tagtccacca tggtatacct gccagtccca tatttaaccc tgtatttact tgattattaa
    37921 aagcctcaaa actagaatca atgtcaccag accatactaa agctccatac ttttgagctc
    37981 ctgcccaagc tcctcttaca agagttacaa cagactctat gtcattatgt aaaccatcat
    38041 aaatcatttt taaataatca ataggataaa tattaccaca acttaaaaca tttccttttt
    38101 tatatctata gttatcaaaa tcatacacag aatagccagg ttcagctaca tctaaccaat
    38161 aatagtcaat cccaagttgt ttataatttt tatctattct atcccaaaca tattctcttg
    38221 cattttcatt tgtcatatct acaaagactg tatttccttg aatttgcatt gtcattctaa
    38281 caccacgatt aacattgact aaatagccat tttctaaata atcattgtag ttttctgcat
    38341 cactttgaac tgtaggccat acagatacta ttggttctac tgaatactct tctttcaatt
    38401 ttttaactaa ttctttagga tttttccaat aatctaagtc aaatttatat tcaccttgct
    38461 taggccaatg aaaatagtca attgcaattg atgaaagctt aattcctctt ttagaatatt
    38521 ccttcacaac atctaaaact tcttctgaag ttctatatct tagtttactt tgccatagtc
    38581 ctaaaaggtt ttcaggcatc ataggaacag ttccagtaac ttgagaataa tttttattta
    38641 actcttttgg gctttctcca caagtaatcc aataatctat aaaatttgta gaaaacatct
    38701 tccattctgt catattttta gcaaaagata cttttccaat tcccggatta ttccataaaa
    38761 gtccataacc tagactagaa atataaaaag gaactgatat ttgagaattt ctttgggcta
    38821 actccaaaac agtattcttt aaatctaaaa atttatgttg atattgtccc attccaaaaa
    38881 tcttttcaga aggctcagat tcaaatctag tagttacttc aaattctcca ctatagcttg
    38941 gtcgatattc tcttgatttt aactttagag tagagttaaa gtctttggta atctcaattg
    39001 tccctacatc ttctccacca tcatcatgtt ttacagctct taatcgaata tattctttca
    39061 ataatatttc atttttatca ttataaaaag taattctatc tctatggtct aagacagctt
    39121 ttatctttcc atttttaatg attgcacttc catcttcatt tttattaatt gtaatatcat
    39181 ctttatttaa cttaggtttt tcgttaagag catagttttc atcaacaaaa ttttggtcta
    39241 caaacgacct aatacgtaaa gagttttttc cccatgcttc tattcgcaat agttcattgt
    39301 caaatctttt ttcaatatag tcttcagata tttttatcac ggctacctcc taaatcaatg
    39361 gtataatatt ctatctttgt gtagcttaag ttaaataatg tcgtttagta tcgttattta
    39421 taaattaggt tttatatata attcatttgt acattaaact aacttaccaa taatatactt
    39481 tatttgactt tgtttgtcaa tcgctttccg gattttagta aaattttcta atatgttgct
    39541 tgaaagtcgt tcttaatatc ttttatttat acttttaata tctgtgatga tacctatata
    39601 catctagttt tttttaaaca catacaggaa taaaatttgc ctattatgta gataatattg
    39661 gacttgaaaa tatgtatagt gaccttataa atacagataa taatatatta gatattgttc
    39721 aaaacaatgg attttataat tataaataat ttatgaaatt atttaagaaa atatataatt
    39781 gtataccaag tcaaaaacga caacaaataa ataaaactaa aaaagatgtt gtctcaaaat
    39841 atagataaat ttatttttca ttgctaaaat gattaaaata tatttgattt aatatacttg
    39901 atttaatata aaaaaagagt gtctcataaa ctaaaaagtt cacttttaga cactccttta
    39961 tatatattat caattcattt attacctctc tacattttct ttcagctagt agatacatct
    40021 ttataagtac taattactcc acttaaaaat gattcaggta ctgtccatca gtcatatttt
    40081 tctgccaaat ataatggtgt ttcataatga gacaataaat atttatatct ttacttatct
    40141 tctctaagct cgtcaaatcc aactataggt atctctaaat tatattcttt aagtagcttt
    40201 tctagctctt ctataaaaat acctttccca tccaccattt gtatatcatt tattttatcc
    40261 atcaattcat tgcaaccact tagctcacca aaccaacgtt tagaactaca tgtcttatta
    40321 taaccacaac ttggactacc atctattgca atgatacttt ttatatcata atcatttttt
    40381 aaatattcat taaactgcct tacatgaggt attaacattt gcctacattg ttctctaaaa
    40441 aacaaattgt caaactgttc ttttacatgt ccccacctat ttattccata cataatcatt
    40501 tctgggcatg gtagttgaat tattccatac cctttattta ttaaatttat cgctatattt
    40561 tgtgctccct taaattctga caatccctct actttagaat tacaatttaa tatacaatga
    40621 catactacta caatctctct atttctcttc ataataatct ccttagttat tcttaatttt
    40681 aatgatacta catattttga taattatatt atttatttgt tctatatttc caatattcta
    40741 tatagaaata tacaattagt aatcttttat aatctatact atgataaatg tatatatttt
    40801 tttaggaggt attataattg gatactaaaa aagtcacatt ttcttcaata tgcatagtta
    40861 ttaatattgt cttaggtatg gttatatcta tgataaatat accattatta tttttagata
    40921 cagttggtac tgtacttggg gctgtcgtat taggtccttt ttggggtgct cttattggtg
    40981 ggtgtacaaa cttagtttta ggtgttatat caggtcctac aaatatacct tttgctcttg
    41041 taaatattgt tcttggtctt attgttggat atatttctaa gaaaaaaggt tttggttata
    41101 aagaagctat tattacagga gtaattttat ctattgtttg tcctttaatt ggtactccta
    41161 tttcagtttt attgtttggt ggtttaagtg gaagtggtgc tgatttattg gttggttttt
    41221 tagttcagtc tggtcagaag atatttactg ctgcgttctt tccaaggatt cttagtaata
    41281 tagtagacaa acctttgtct tgtattatgg tggtatattt tataagtaaa atgcctaaag
    41341 gttttataaa acaatatagt aaaaatactt ctagttcata ttaataaatc atttattatg
    41401 taagatttat tactctttaa aatgctatat actcattttt atataacatt tttattaata
    41461 atttaattag atagtatttg tattatttta attaaacgta acctcttgat ataaatttga
    41521 gctataaatc tatatcaaga ggtgctattt tatttttaat ataattaata ttctattacg
    41581 caaaaaatgc atatatttca ttattttatg gaaaatatta cttcatttaa ctctatatca
    41641 aactcattaa gtaaaaatct aattatattt aatttagcct ctgtatttaa atttgtttct
    41701 aaatatatat tttctgatat tttaatacct tttcttaatt tatatacatc tctagactta
    41761 atattatcta taaaatctct tttataagtc ttgtctacaa tactgttaaa ccttacagaa
    41821 tccaaatcat ataaagtaag agcaacttgt tcataaaatt ctgtccaatt tttagcctta
    41881 tatgactctc ctaatatact aaatgatact atactttcat ttgtaaaatt aacatcatca
    41941 tcctctaacg taaatatatt ttcactgtta cttggaggtt catatgtaac acttggatat
    42001 ttccaaattt ctacagctct atctagtaat atcttagttc tattttttat ttcttcttca
    42061 ttccatttat ctatagatga aatatattta tttagataaa gcctactatc tttaaatcca
    42121 tcttccattt ctttcttttc ttcaaatgtt ttattactta gttttgaatt atatcctgtc
    42181 aaagttaaat ttccaattgt atgtaaatat ttatcatgta tctccttata gttatctcct
    42241 agtgattcct tccatttatt tgttaatgtc tgtggcatta tatgctctat atttagcata
    42301 ttattattga ttaaattttc taaatcaaca atttctttat tattataatt ctctaacctc
    42361 tcaagtatat ataacttatt ctttgactta gtattatata tatctttagt ttcaaaagca
    42421 tttgaaaatt cactgtcagt aggaaatctt tgagatgatt tcttatttat aaaaatatat
    42481 cttaatatat tagaatagtt ttctttataa tcactaaatt ttttaatttc ccttcctaag
    42541 ttcataaata ctttattcag tgcattcgga ggtacatcac atactattct tcttaatata
    42601 aaacattcta ctaaattaag ggattctaca agtacttttt tatttattat accttcatta
    42661 taatcattaa ataattctaa tataaacgga tatgatacaa atatttcaag tttgtttatc
    42721 cttttcaaaa ctttgtttac atcattatca tcagtacatg aataagatat ctctctataa
    42781 tagttagaaa atttaagtaa atcttttaat aaaatttcta tatctatacc attatctgat
    42841 acataccttt taaaactaaa atatacttta tttttattcg gtatacttct ctcctttata
    42901 gtcaaatagt ctcttataaa gctacttacg ttgctacttg tatttttttc aattttatac
    42961 caataattat tataaaattc ctcttgtaac ttagagcttc tacccattaa cacaaagttt
    43021 cttactctat cagcttcact taaatctaag ccagttgaat ttagactttc aaagattaat
    43081 tgagggtcat cttcaccatt ttttaactct atttctacta tagttaattt ctgtatagca
    43141 tcaaacaaat catctattga tatattatct tcttttattc tattataaaa atataaataa
    43201 tttgaaacta tattagaatt tctatctgta ttcatttctt cttcaaatag ttcatagtaa
    43261 gcttttctat cttctgctat tggttttaac tttatttttc catctttatc tcttgagtgc
    43321 ttgtttataa gataacactc cttaatctgt tcttctgttg taataattcc ttttgattct
    43381 ccaaactctt ttattatttg acacatggca atcaataata ttgacacagt agtcactctt
    43441 tgttgtccat ctattattaa atattctttt cccatactat atatagatac aactgaccct
    43501 aagaaatgag ttctaaatcc agaatctatt atatcctcta aatcatcaaa caatctttta
    43561 cattgttctt tcttccagtt ataatttctt tgatatacag gcactacaaa acttttgttt
    43621 gacccctcta aataactaag aaattcaatt tctcctgctt tcatattaac tccccctata
    43681 agttaaataa attccattca taactccatg tatctatata ttatatcaaa attttgactc
    43741 ataaatgtat atgaaagcct tattatatac ctttttatac ctatttttat tttattaaag
    43801 taaatacatg attattctat aaaatataca aatacttaat tttaaaaatt attatttaat
    43861 cttcttcatg agtaattcat agttatttat caattaaaaa gagatattgc ataattattc
    43921 aatacctctc tttgtatatt tacattatcc atatctagtt atctatttca acccaatatt
    43981 agactaccta ctaataaatt tattctctac ataattaaca ataattttgc actaaataac
    44041 atcattagcc tatctctgat gcattttctt taattttatt tatagtttta atcaatttat
    44101 ttctctcttc aatatgattt tcaaataaat caattatact tccaacagtt ctaaatgggt
    44161 cttccatcaa cactttgtta tcctctataa atccattctt gactacataa tcgactataa
    44221 gtttaacaaa atgtatttgc ttagtattaa aactcttatt atttaaaaac tctgaaaaag
    44281 cttcatttgc agcttctcta tccaatccca ctagttttct cactaattga cttactggag
    44341 tatctccaaa ctccttttta taatcatcac aattacctaa ctgctttaag agtatttcct
    44401 ccaacgtttc aacatcttgc tttgttatct ttttattatt tcttaattta aatattgcta
    44461 attcatcttt atggctattt aaataatact ctaccttctt tttataattc ttaagattgt
    44521 ttgcattata tacagaatca tttctatctt ctgctacaat catatcttca aaacttgtat
    44581 aatatatctt ttgactagac ttttcaagat acttaataag ctctcttaat gatatacgta
    44641 cttcttctac ctcaaatata tctgaatctt cccaaaaatc ctctgtcatt gctttttcaa
    44701 tagtatattt ttgttgctgg atctgtggta tagtcccaag tttcgaaagt ttttctgctg
    44761 taaccattac atgccttatc cctttacttg cattattatt ttgtaagtat gcaagttgta
    44821 tattatacat aactacatca aatcttttag ccaattcatc atcactatat gaagttatga
    44881 gtggtgatat atattctctt atctcatttt gtgctactgc tccaatattg ctccaaacat
    44941 tttcattttt atacttatgt acataactta aattcatcct aactatataa ctatcctcat
    45001 ttaaagcttt tacagaagtt ataagttctt ctaacaattc ttttctaagt tctgcatact
    45061 taccttctat atatttaata tcttgaagtt ctttaaccat acttaccttt atattaaata
    45121 atttttcagt aagtgtttct gctttatttc cctcaaatcc tttaggatta aatttaaaaa
    45181 attcaaaatt attacaaaaa tcaaatatta agaatctttc cttatccata tcaacaccta
    45241 ataaatctgg acataatcta gttcctctac ctatcatttg ccaaaactta gtcttacttc
    45301 tcactttctt gaaaaaaaca agatttagga tttcaggtat gtcaattcct gtatcaagca
    45361 tgtctactga aactgctatt tgaggtaatt tattcttatc agaaaaatca tctattatag
    45421 aatctacata atttatacta tagtcaactg cttttacaaa gttcccacca tactttggat
    45481 acagtttatt aaatctttca actattgccc tagcatgctt tgtattcttt gcaaaaatta
    45541 tagtcttacc aatcttttct tctccttcta ttttcaaccc ctctgtcatt agcttattta
    45601 aaactaaatc tattgtgtca gaattaaata gccactcatt tactgcatta ttccctattt
    45661 cgtctccaat actctcatca tcattaaatg tattttcata ttcttccttc tcttcatcag
    45721 aaagctcatc atacttaatt ccatcttcca taatcttagt cttaaactca atactagtat
    45781 aatctactaa atatccatcc tcgactgctt tattatactc ataagcatat gtaggtactc
    45841 cattttccat gtcaaaaact gaataagtat ttttatctat ctcatccttt ggtgtagcag
    45901 taagacccat taagtaagaa tcaaaataat caaagattga cttatacttt ttataaatac
    45961 ttctatgcga ttcatctatt ataattaaat caaaatgacc aggtgtaaac aatctctttc
    46021 catccttaga cttcgtatca tcaattgcat tcatcattgt tggatatgta gaaaatatca
    46081 tcctagcatc ttctgggctg tctttgctat ccaataaatt acataacgcc aagttaggta
    46141 atagcttagt aaaacttttt ttagcttgct ttaccaatgc ttttctatct gctagaaata
    46201 atatattttt aatccaatta tgtcttgaaa gtacatcaac tatagatata gcaattcttg
    46261 tttttcctgt accagtagca cataccaaaa gagttttgcg ttgcttattt tcaagagcct
    46321 cacatacagc cctaatagct tctttttgat aatatctatt ggatatttca tcatttattg
    46381 ttacagaact taaagacttc ttactctttc ttctatctat cataagttgt aattctgatt
    46441 ttttataaaa tccataaact tttctatctg aatagtcatc ccaaatatac atatcaaaac
    46501 cattcgtcaa aaatattact ggtctttgac tatatctctt ttccaaacaa tctgcatata
    46561 atttagcttg ttgttgacca attttcgggt ctttgctcgt tcttttcgcc tcaactactg
    46621 ctaatggctt accattttca ccataaagaa cataatctac atatcctaca ccactttcat
    46681 taggcatacc ttgtacttct atttcctccc ctatatcttt tccaaattcc caacctgcaa
    46741 gctttaattc tatatttata tatctttttc ttgtctcaaa ttcgtttact tcgtctatct
    46801 tgaaatcgta gtttacagta ttaacttttc tcttttcagt tagtgacttt cttaatttct
    46861 cattttcttt tattacttct tcaagctttt tatcttttga acttaatctc tcataaagat
    46921 ttttaagctc gtctggtctc gtccttttct cttccccatg aagtaataaa tcttcattaa
    46981 agtcttctgc tgtatattca tctgaataac aatagtctat ccaactaaca aattgatgca
    47041 aattgttaag tgaaagtatt gcttctcctc tctctatgtt cgcactagta tgtacagata
    47101 aattacctaa tttaactata tattttaata aaggtaacat atcatagtct ataagttcta
    47161 taaaactatt attatgaatc aacgtactaa gattatcttg ataaggcaat actaaatcac
    47221 tatcattagc atatagccat tttactgcaa gctctaaagc tcttcttgtt atagttgcac
    47281 aagtagatgg gctaactagt atactttttt ctgcttctaa gcaagcagta ttaaaactat
    47341 tgaaattttt cttcttttgt aaaaagtcaa aattacccaa ggcttttctc ccccttttgt
    47401 cccttagtta aaataaatct ctctaaaaac tatttcttac agctgtttct tatactaaca
    47461 aatacttctt cattttctgt aaacaattcg tacatatctt caaactgtgg tatatcatat
    47521 ccatgagaat catcatttct caattttcta agtgtttcta taactataga agaattttta
    47581 ggtaataaat tgtgatactc acaagctaaa aggtagtcat aaaagttttt agattttatg
    47641 tttaaatcaa ttgatttata atacaacatt gcttttgtta attctaaaaa tgagaccata
    47701 tagcttttaa aaccttcttt tatgtatcta gcccataact caggcatttc ttccttatca
    47761 tataagattt tgaagttttg caggtcatat aagcaagaac caaaatccct atttacttct
    47821 tctattgagt tccaagataa tttgtttcta attaccatac atgtccctcc aatctaagat
    47881 atctattaca tcactgtttt caaaatagaa tttatttata taatccttaa aatctttaga
    47941 ttcataaata acttcacctt ctaaaatagc ttttttaagt gctattgtat aattatctgt
    48001 aacaattttt aggtctacat caatgtctaa tatatttctt agagcttctg tcttagttgc
    48061 aagttctgta attggtactt ttttgatagg aatccaagct atgtctatat cgctttctga
    48121 tgtatgttta tctgttccat aactaccaaa tattatgatt gctagagtat tttcttttgg
    48181 aaatacattt attattgagt ttttaatctc atttggtata tttctcattt aatcacctct
    48241 tgtttattag gtaatattgc ttaattgaat ttatatccat aatcttttaa tctatttata
    48301 catatttctc tttcttcatc agtaaacaac tctttatact tttcttttaa tactaatact
    48361 tctaatgata aatctaatct cttacactcc catagccttg taaatccttc agtagctcct
    48421 tctttattga ttaattcttt agcagctaat aaggctcctt tgttatttat cagttgtaaa
    48481 aatcttgttg gcttatagtt acattgtaaa tcagcttctt tatagatatt taccatgtca
    48541 tgatataaat ctagctctat ttgattcata gattttattc ccccatttta atacttgtat
    48601 ttcagttgaa caattctcct ttaaaagctt tttgcattaa tgagttaaag ttatcttcta
    48661 gttcttttaa gctagtttcc atttcaaact tcaaagagtt tacttgttta acgaagttgg
    48721 caaattgatt ttgaagtcta ataggaggta caataatatt tatttttcta acagcatctt
    48781 tagttatcgt ttttgttaca gctcctctta ctttctcttt tattttactt tccatatagg
    48841 atgttagtaa aaggttatat aagaatatat gattcacttt atcttcatta aatctaagca
    48901 taaattgatt catagctaaa gatactggtt tatttaaaaa tggcattaaa taaactttac
    48961 ctgcactacc tatcttattt attataacct caccaccaaa cacctttgat ttttcaagat
    49021 aattatatgc atgttcatcg atatacttaa cacctttttc aaagttatta ttttctaaat
    49081 ctgtagttct taccattaag gcataacctt ttgtatctaa aagagttaca ttatctctta
    49141 aggtttcata actaccattt gaatgataat cagttaaaac atctaaatat ttccctattt
    49201 ctgaaatttc ccagtttttt tcgttctttg atggggtacc aaacatctca ataaatcttg
    49261 atttaactaa ttcatccaat acttctattt gctcttttct tttatctatt aactcttgag
    49321 ccttgtctaa aacacgcact accttttctt gcacttttaa attatacatg cgtattttta
    49381 tattagctaa tccttcatta tttaaagctg attgtgtagc acctttactt aacctatttt
    49441 tttgatttag aaaataacta ctatttaagt aatggtataa atattgaggc aatatttctt
    49501 ttgatggttt taaaacataa aagccagtcg atactattat atttttatta gttttattaa
    49561 taactagtgt tttctttgtg tccttcattt ttgcaaatat aacttctcct atatttacag
    49621 tttgatttgc tctagaaggt ttattttcat aagtaactat ttctagattg cttatcttgt
    49681 taaaatctaa gtttccagta ctaagatatg agcgttctcc atcaaacttt tttacatttt
    49741 ccctgcttat actaacaaca tctaaaattt ttgcttcatc aaccatactc tacacctcta
    49801 acattctttc tagttcctct aatccatcca ctatctcttt ctctaacacc ttaaccctac
    49861 ctataataac actaggagca tcataaacta cttcctcata cactacctct ttatacttat
    49921 taatagataa atcataccca ttctctctta tctcttccac atcaacaaaa aagctttgct
    49981 ctgttctttt tctatctact tccccatcaa gattatcaaa tctcttaata atatcctcta
    50041 tatcactatc ctttatctca tttctcttat catccaaaga ataaccatca gctttcatat
    50101 catagaacca taccttatca gttccacctg tccctgtttt agtaaatatc attatagctg
    50161 tagatacccc tgcatatggc ttaaatacac cacttggcat tgatattata gcttccaatt
    50221 tatgattatc aactatttct tttcttatcg atttatgtcc acctgttgaa ccaaacaata
    50281 ctccatctgg cactatacat gcgcatcttc caccaatttt taaaactctt aaaaaaagtg
    50341 ccaagaataa taactctgtt ttctttgtct tagtcacttt taataaatct gctgacactg
    50401 cttcataatc taaacttccc ttaaaaggag gatttgctag caccaatgta aacttatctt
    50461 tatctgtatt aacctccgat aaagaatcct tatactctat attaggattg tcaacgccat
    50521 gcaacatcat attcatagca cctattctaa gcatagttct atccatatca aatccataga
    50581 acataccatt attaaaatgc tccttcagcc cttgcactaa gaaaagactt gaatgattat
    50641 cccttaagta ctgttgtgat gatactaaaa aacctgccga acctgctgcc gggtctacta
    50701 taatatcttc tggtgttggt ttaataagtc ttactatcat atctattatg tgtcttggag
    50761 tcctaaattg accattagta cctgctgtag ccactttgga taataaatac tcatacaaat
    50821 ctccctttgt atctctatcc ttacttaatt ctaaattact aataccatca actattttag
    50881 ataacataag aggcgtagga attttaaata ttgcatctcc catgtacttt gcataagctg
    50941 attctttatt tccatgtaat ttttttatga aaggaaacac ttcattttgt actatttcat
    51001 acattttttc tgagtttcct tcattagaaa acttactcca tcttaaatgt tgatgttcat
    51061 catcaaatat cttttcaaaa gaaacaccca aaagagttgc ttctgcttca ttttttgttt
    51121 ctacttcatc caatccttta ataaataaaa gatatgtaaa ttgttctata acttctaatg
    51181 gattagttaa tccaccagtc caaaatgtct cccaaatctt gtctacttta ctccttaatt
    51241 ctcctgtaat catatatgac tttccctcca gtgttcataa aataatttaa atatatattt
    51301 tagtcgtacg ccttaatagt tagtgtctta tgttaaatcc aagtttttac tacacaatta
    51361 ttaaattatt tttcccattt acatatttta gctaaaaaac taatgcaata ctcttatttt
    51421 atgattatta tatataccat acaaaattat tttatcatat atccatcata gaagtcatct
    51481 acctggataa ctcttaccat attataactt tttaatatta atttaaactt agaaagaaat
    51541 tttttattta attatatcat cttccttatt tcaaatttct caactacaat cctaatcaaa
    51601 aaataaaata agatgctgtc tcaaaataga tataatcttc ttttttattg tcagaatgat
    51661 gaaaatatat ttgatttcac acaaaaaaga gtgcctcatg aactaaaaag ttcattttga
    51721 gacacccctt aatttaatct tacttattct ttccctttat tattaacact tcactgtccc
    51781 tattgctttt cctacacatc cacaaacttc catcctactc ttaacaaaat ctttaactga
    51841 ctctaaacct tttttaccat atttcttagg gtcaattacc tctgggtcag aattaagcac
    51901 atccttaacc ccattgctat aagcaatcct taattcagtt gcataattaa ctttgcaaat
    51961 acctcttttt atagattcct taataacctc atctggtatt ccagacccac catgtaatac
    52021 taatggaact gatacaacct ctctaatttc agataatcta tctaaatcaa gctttggctc
    52081 tcccttatat agtccatgtg ccgtacctat tgctactgcc aaagatgata cccctgttct
    52141 ctctacaaac tcttttgctt ctaatgggtc tgtatatgct ccaccatcac caccatctaa
    52201 atcgtcttcc ttacctccaa ctttgcctaa ttcagcctca acaggtatat ctgaaggcat
    52261 acatgcatct acaacagatt tagatattga aatattatct tcgtaacttt catgagaacc
    52321 atcaatcata atagaagtat atccaactct aagtgcctgc atagctagtc caaagcttga
    52381 accatggtct aagtgcattg ccactggaac acttgccttc tctgatgcta cctttacatt
    52441 cgctaaataa taatctagcc ctgcatactt tattgttgaa ggtgttgttt gcaatattac
    52501 tggtgattta agttcttcag cagcctctat tactgccata accatctcca tattttcaac
    52561 attaaatgca cctactgcat aatgcccttc ttgtgcatct aataatattt gtttagttgt
    52621 cactaatgcc ataatttctc ctcctatatg tttatactga tttgatttct tcgttattta
    52681 attttgatac tatttctcta cttgttttgc tatttaataa ctcatttaaa aattcttcat
    52741 tcattaattt tgaagatagt tgagataatg tttttaagtg taaattatca ccattatctg
    52801 tagctgatat cataaatata atatgtgcca agcttccatc ttctgattca aagtcaaacc
    52861 cttcttttga tacacctact gctacacgtg gtacctttac tgcatctgtt tttgcatgtg
    52921 gtatcgctat ccccatacca aaacctgtag atgatatttc ttctctttta aggatttctt
    52981 ctttaaactt ctttttatct aaaagaacac cagatttatc aagtattcca atcatttcat
    53041 caattacatc tgttttattt tttcccttaa catctaaaat tactgtttct tcgctatata
    53101 aagagatatt attagatacg ttttccgatt ctgcactttc atttttatgt ccatcttttg
    53161 ttgcatttgt attttctata gtatttttct catttactac tttaggtgta accatcatat
    53221 aaagtacagc acctactaat gaacctacaa atatacaccc tacccataaa agtggcttat
    53281 tgactaatcc tagaaccaaa aaccctccat gtggagctgg tacttctatt ttcattatat
    53341 aagttaaaat tgatgatatt gatgatgcaa tcataagtac tggcaacact tttaatggat
    53401 tttttgctgc aaaaggtatt gccccctctg ttatatgagt actacctagt atataattga
    53461 ttaatcctgc tgctctatct tcttctgtaa atctattttt aaataaagta gatgctattg
    53521 ctattaccaa tggtggtgtt atacaagctg cagatacacc tgccataaat aaataatttc
    53581 cctgtcctag aagcatagtt ccagttacat atgctgcttt atttactgga cctcccatat
    53641 caaatgctga catacatcct attactattc ccaaaattat aggacttgaa ttttgtaacc
    53701 ccgatagaaa gttcatcata gcattgttaa gtgctgaaca tggtccacca agtaacaaca
    53761 ttgctacacc cacaagacct acgctgacaa taggaattat aaaaatcgat ttaagacctt
    53821 ctaattgtcg tggtaatttt cttaacaaat gtacaaatag tttaactaag taacctgcta
    53881 aaaatcctga tatgattcca cctaaaaacc ccgaacctgt atcaaatgat atcattcctc
    53941 caacaagtcc tgccaacata ccagctcttc ccgatataga ttgagctata aatgctgcca
    54001 atacaggaac catcaagttc atagaatatc caccaacaga ttttaatgta gctgctattt
    54061 gattatattg ttctgaattt gggtcaaatg aataaatccc ccataaaaat gatatagcag
    54121 taagtactcc acctgctact actaaaggta acatgtgaga tacaccattc attaagtctt
    54181 tatacaactt ttgaccaaac gataaatttc cttcttctgc aattttactg cttgataagt
    54241 ttccttttct aatagctact tttccatcaa tacacctttg tataagttca ttagccttat
    54301 gtataccttc tttgacaggt acttctatta ccggctttcc attgaatctg tccatatcaa
    54361 catttttatc acaagcaact attattgcat ctgccatttc gatatctttt gctgttaact
    54421 tattttctac acctatagct ccattcgtct caacttttat gtcacaccct aattcccttg
    54481 ctgaattttt taatgcttct tctgccataa aagtatgagc tattccagtt ggacaacctg
    54541 ttacccctag aatcattttc tttcccatct ttataccacc tttctgactc ttatattttt
    54601 tatataatct tccacattct ccaaattacc tataccatta ctttcagcca cacttgctcc
    54661 tgttgctgct gaccttttta atgcttcttc aatatgttct ggattttcca accatatact
    54721 taaaaaagca gctaatgcag aatcaccagc acatgcagag ctgactactg taactggttg
    54781 agcactagca taataaattg attttccatt ataaaaataa gaaccttttt ctcctaaagt
    54841 tagcaatata ttttgagcac cttttaaatg cagtaattta agtacatcct taatatcttc
    54901 ttcatctctt acaataattc caaatatatc tttgatttct tcatcatttg gttttatcaa
    54961 atatggatta tactgtagta actcctttaa ttttggtgaa cttatatcga gtattgtctt
    55021 tatactttta tttttacaaa ttttaaatat atcctcatag taattatcat caataccagg
    55081 aggtagactt ccacttattg ataagtaact tatatctgct aatgactgta tcttatctag
    55141 catatctagt ttttgttttt cgtttacata tgacccagag tttacaaatt taaattcatc
    55201 acttccatca tttaaaaata tatttatacg agttgtatct tctacccaag taggtaatac
    55261 gtcaaatcct ctcttttcgc tttcttcaac tatatatttt cctgaaaatc ctccaaaaaa
    55321 tcctaatatc ttagattcta taccataatg acctagtaca aaagttacat ttaatccctt
    55381 tccattagga gaatatacag catttgatgt acgatttact aattttctct ttatcccatt
    55441 agtagatata ttcatatcta ttgcaggatt cgtagttaat gtatatatca ttgtcttccc
    55501 ccttgcttgt gctgtgtatg ttttcattat aataaaaaag tctatgaaaa tcttttcaca
    55561 aatagaaaat cgattttcat agacttttca atttaatttt cagaattatt atatctgacc
    55621 atataatcta taattatcct agatataata tacaagggca atctggaaga tacttcatat
    55681 tcagaaattg atatatgttc atgtttgtat cctacaatat ataaatccga atactttata
    55741 agttttgcac tttcactaca acagcaagtt ataaccttag ctccaactaa attggcattc
    55801 tgtgctgatt ctacaagctc tatggtattt ccattcaatg aaaatatgat tataagttcg
    55861 tcttttttta ttgatttaga ttttattttc attatgttgg ggtcatttat aaaaacaaca
    55921 ttaaaatcaa gtaattgcaa tttaagacta aactcttttg ctacatattc agtaagccct
    55981 cttgccaaaa tatatatctt actagattta tttatagttt ttattatatt gattagtgta
    56041 gttaaagata tttgttctat aactctctgt gcttctataa aggatttatt tattatatcc
    56101 cccatatttt gtatatcatc attttcatct tttactgtta atctatacct aagttcattg
    56161 aatccattta aaccacattt tctaattgct cttgaaacgg ttgctggaga tgaatatgtt
    56221 tcatgagcaa tctctactat agataattct ggtaatattg attcattttc atttataaat
    56281 ttaattattt caagttccgt cttcgttaga ttttcagaat tacttttgtt tagctcaatt
    56341 atcatatgtt atctcccctt atataagttt tatttgtcta aatttatcga gtaatataat
    56401 atattacctc ttaactactt atttttatat acaattaaga tttagtcaat gtctatatat
    56461 gtaaatttat aatataataa ttttatgctt caattaatta tgtaattatt agagtatttt
    56521 gtaataaaaa ttggagttac tcaattactg aaactgagta actccaattc ttacagcctc
    56581 aaattaactc gaattattga aaatgattca taaacattat cctatactct cacttatcaa
    56641 tttatatact tgagtaatac ctttttttat taacagaaat catcttacta acaattgaaa
    56701 ttgtagttcc agtacataat attgaaaata tagttccaaa ccctaaattt ccgcctaaat
    56761 atacacctaa aattaaaaat attaaatctg ctatagtttt taaaacttta tatggatact
    56821 taaatttgcc ctcaatatag attaatatag catctaaagg gctcattcca atgtcaaatt
    56881 ttataagcat tgcaaatcca ctacacataa gtatatgtcc aattataaag ctcattattc
    56941 taatgataat ccctaaacta cttatattaa aatctaataa taaatatata tacaaatcta
    57001 taaatattcc tgctactaat acataaacac agcttcctaa tcccaaactt tttttattca
    57061 ataacaatgc tataagtaat agagttccat tatatattag ccctgctatt gtataactta
    57121 tacctaactt tatatgtata ccctcattta aaagtgtaat tgcatcacta ccaaggcttg
    57181 actgaagtat aagagatata ccacatccca gtatatttat aattaaaatt acaaatataa
    57241 atttttttat gacattcata attaataaac caccttattt ataattataa tccctcttat
    57301 aaaactgtat taataacata gtatttataa gagggattat ttatatttaa aaactatcta
    57361 ctttttcttt taattcttct ccattagttc ttattacatt tttataccaa taaaaactat
    57421 cttttttgta acgttctttg cttccatttc cattgttatc tatatctaca tatataaatc
    57481 catatctttt ttccatttct tgagatgaac aacttactat atctattggc gaccacatac
    57541 aataagctaa tatttcggtt ccatcagcta tagcttcacc tatttgttct atatgttttc
    57601 ctaaataatc tattctataa ctatcatgaa cttttccatc ttcaaattta tcatgcattc
    57661 caaatccatt ttcagctatc attattggct tttgatatct atcataatat tgagataaag
    57721 tattgtataa tcctttaggg tcaattgccc acccccaagg atttgctttt aagtattgat
    57781 tttttacatt atcaattgga ttcatggtat ttttacttgc tgatactgtt gtagagtaat
    57841 agtatgatag agctagaaaa tccatagtat tctcttttaa cactttatca tcaccttctt
    57901 ccataactat atttatgtta ttttctttga agaatctctt aatataagct ggatactccc
    57961 ctctaaaact tacatcagta aaaaaatatt gtattctatt tctttttaaa gcaaatacta
    58021 cattttcagg gtcgcaatct tctggataag atgtacaatc tgccatcatc atccctatca
    58081 tcatatctga atttatttct tttccaagct tcttagttaa agctgtagcc atgaattgat
    58141 gatgaatagc ttgatatttg gcctcttcta catcatctac ctggtctaca caaaatgcaa
    58201 ctgaattaaa tgattcatga tacattaaat ttatttggtt tataactatc caatatttaa
    58261 ctttatcttt gtatctattt aatattaatt ctgcatatct aacaaagaaa tccactactt
    58321 ttctattaga ccatccttta tattttaata ctaaattcaa aggagtctca taatggagta
    58381 gtgttacaat aggttccata ccattatcta ttacttcatt tataagatta tcataaaact
    58441 ttaatccctc ttcattaggc tctaaatcat ctccatttgg aaatattcta gcccaattta
    58501 ttgaaaatct aaaacacttt aaccctagtt ctttcaaaag ctttaaatct tctttgtatg
    58561 tatgataaaa gtctattcca ttacgcttag gataataccc attattatct ttcatagcaa
    58621 actttatttt atctacagtc atatcagact cgtaatgttt agatatatct ctatctttat
    58681 catacatatg tacatcagct aagcaccacc ctttgccacc ttcattccaa gcaccttcta
    58741 attgattagc tgctacagct ccaccccaca aaaaatcttt aggaaactta ctcaatttaa
    58801 tcactcctta ttttatttat ttaaatcatt tactattatt taccttatat tctatagact
    58861 ttactattcc tactaaagac atagttatat ttaactcgct gaatattgtc ataagagtat
    58921 cttgagcatg tgcaaataaa agtgaatgtg ctcttttttc tccactagct tccccttgta
    58981 taatgttagt ttgagctcta tgtgcttctg tcataaactc ttttgcttta gctagtttta
    59041 aatcagcatt tttataatca aacctttcta aatcattaag agcatgttta atttctgttc
    59101 tagcctcacc tgcacgaagt attatttgca ttgctacttc tactaattct tcatctatta
    59161 catgttcttc agttgtcata tttataattt cctttcaaca tctaaattta agcttcttga
    59221 ctctctaatt ttagttcttc tttttcataa gctttaaaaa atggatacca tatcatgaat
    59281 agcaatacta tatttattgc taaaacaata agccctctaa catcttgatt taccataaaa
    59341 gtagatatac caaaaggaag ataccataaa ttaaacacct tactcggaat tgtcacaaat
    59401 cccatactca ttgataagta agtagttatt gatattacta ctgttcctat ccacataggt
    59461 aacattaaaa atgggttcca tgctactgga gctccaaaca ttactggttc atttatgttc
    59521 attatagaag gaacgataca ggctcttccg attgctttta ttcttccagc tctagataaa
    59581 cacatcatta gcactagtgg taatgttgct ccccacccac ctaaagttat ccaacctgtt
    59641 tgaacaactt cataagtata tatattagtt gcaagccctc ctgatgctac agctgctgca
    59701 ttagctgcaa ttgcactaag ctgaattgca taagttattg gggataatac ccatccactt
    59761 atacctaaag aatataaaaa tactactaag aagtttaata gtacaaatcc aggcaatgtt
    59821 tgtgctatat ctgatactgg tttaaatatc ctaactatta tttcaaacat atcaaagtta
    59881 agtccataaa ttagtcccca acctataaac attattactg ctataggtaa catactatca
    59941 aaccacttac ttacaaaatc aggaagtgct gaatcttcac caaaaaatga gaaagaccca
    60001 aataaagaca ttattaatcc ggagaataat cctgcaacta gtgctacaag cattccttct
    60061 cctccaaatc tattgaagtt aaatatagct ccttcattcg taatctctgg acgaatcatc
    60121 attaacatta atccagcacc tgcaagacca gctactacac tcatactttc aaatttctta
    60181 ttcttcatta tttccatagg taataaaaat gctataaata gtcctaaaag tccaaatgta
    60241 tattgattta ttggacttaa atcaggtaag aaacttatgt aattcttcaa gacagaaact
    60301 atagttacta aagaacctac aaataccata ggcaaaactt tcattatagt tgattgaact
    60361 gattgtaccc atatattctt agttatctta tttacaacag gagtaaactt ttcacttaac
    60421 aaatctataa atttattcat aaacaatctc cccatagata ttttatttgt ttaatattaa
    60481 ttctaatgct tcttctaaag cctttacacc atctaatctt ccatatgctg ttttagatat
    60541 acatgctact ggaacattat attcatcagc ttttttttgt atttcatctt tcatataatc
    60601 taaatgtggt cctaataata aacaatctat ttctggtaaa tatttatcta tctctgactc
    60661 acttctagct tttatatctg cttctatgcc ttttttcttt gcactctttc tcatactagt
    60721 tgccataaaa cctgtacttg ctcctgagcc acatgccaac aacactttta tattcttcat
    60781 aacaatacct ccagtatttt tattcattaa tttatttctt aatgaatttt tatttgattt
    60841 gattgtattt atattgtact tcctaaataa tttcctttca cataaatata tttcctaata
    60901 ataggaaatc atttactctt aaccagacac ataaatatat agtataatgt acattataat
    60961 acgtacattc aattatataa atatcatatc atacagattt tattttaaaa ctatgagagg
    61021 gaatctaatg aaaacatcta aaaaagagtt atttttaaac ttcataaaaa cgcaacatga
    61081 ttggatagat tcatccacat tagctaatta tcttaatgta tcaacacgtt cgattagaaa
    61141 atatgtaaat gaaattaatt ctactggtga atttatatta tcctctaaaa aaggatataa
    61201 agtaaatctc aataataact gtcaaaccaa ggttgatagt tcagaaaata tatcacctga
    61261 taacaggtta aatttaattt taaaagaact tatagttaat agtaatggaa ttaatatatt
    61321 tgatttaagt gaagaattgt ttgttagtcc agctactatt gaaggggata tagtcaaagc
    61381 taataaattt ataggaagtt ataatttaaa gataaagcaa tcgaaatttt tattgaaact
    61441 aattggaaat gagtctgcaa agcgcaaatt aatgagctct ataatattta aagaaacggg
    61501 aagtgatttt ttaagcttat ttgatgtaca aaaaatatat caagagtata atttgaccaa
    61561 actgaaagaa aatataatat atatattaaa aaaatacaat ttgtttataa atgagtacgc
    61621 tataaataac atacttcttc atttaatgat aactatagac agaataaaaa agaataacta
    61681 catagaatct gtcgaagtag taaactacat agataataat aatgatataa gcatttcaag
    61741 agatatatca aattttttag agtctgaata caatttaact ttaactagtg cagaattata
    61801 ctacttagta tttcagttaa caaacaaaac cacagtctta aattatcatg aaatggatac
    61861 taagtcattg ccaaattata tagatgaaca ttttgttaaa ttaactaaaa aaataattaa
    61921 aaatgtatat gacttatact ttatagattt atctgatgat gaatttgttg taaaatttac
    61981 tcttcatgta aaaaatttaa tcagtagggc taaaaataat caagttttga gaaatcaaat
    62041 acctcagaag ttaaaagatt cctaccctct gatatatgat atatctgttt atatttgtaa
    62101 tcaaattcaa attttagaaa acatagaaat agatgaagat gaaatatcgt atatatctct
    62161 tcatgtaggt tcattttttg atagacaaaa attactagaa gataaaattc tctgtgcatt
    62221 aattactcca aattactatg atttacaatt caaaatagta agagacctcg agaagagatt
    62281 taatgaatcc atagaaatta ttcaaatttt ttcagatact cataatcttg attttgacaa
    62341 taaggtagac atggttatta ctactttacc aattagtgat agatgcccta taccttttgt
    62401 ttatgtaaat ccttacctaa acagaaaaga ttatgataat atccaaagta aatttattca
    62461 gattaaagat agaaaaaata tacttactgt acaaaatcat ttagaaatgt actttagtga
    62521 atctttgttt atgaaaaaca tatatttaga tagtgctaaa gattacataa aatttatggg
    62581 aaatattctg tacaaaaata aatatgtcaa acccaattat atagatgatg ttcttataag
    62641 agaaaaaatg tcttcaactg catttaataa caatgtagca attcctcata gcatgaaaat
    62701 ggatgcttta aaaactggag tatgtttaat tgttaacgat aaaccagtta aatggggtga
    62761 ggaaaaagtt caaattatag ctatgatacc tataaatgaa aaagaaaaag aaaaattcaa
    62821 ttacatattt gaaagcttta ttgaaatatt atctgagtgg aataatgtta aagaacttac
    62881 taaggcagat aactacagta gttttatgaa tagaatagct tatcttattc aaaatatcta
    62941 aatccattaa tttatttcca atatatgttt cttaagttat taacacaaaa tagataagct
    63001 gtcacactaa aaagtctaaa ttaatatgtg acagcttttt acctaatata ctttgcttta
    63061 atactacata ttttttgatt gttgtatact agttataaga ttgaatattt gtgttgttgt
    63121 agctgtcata ttctcactag cagttgcttt atccattgct tcttctattg tcatagctct
    63181 atttactata gaaaaataag catctatacc ctcttcatta catttaactg catcttctgt
    63241 tgtggctcca gccaaaccta ttacttttac cccatatttt tttgccagtt ttgcaactcc
    63301 tattggagcc ttgcccatag cagtttgatt atccaatcta ccttcaccag ttatgacaaa
    63361 atctgcatct tttaactctt cctctaattt aatttcttct aatattattt ttattccaga
    63421 ttctaatttt gaatttaaaa atgctaaaaa agcaaaacct aatcctcctg ctgctcctgc
    63481 tccttctaca ttagctacat ctttacttaa gtaattttta actactttgg aaaaatttct
    63541 aagcccatta tctaactcct caattatttc tgatgttgca cctttttgag acccatatat
    63601 gtatgcagct ccatttttcc caaacagcgg attatttaca tcacaggcta ttttaaactt
    63661 acattcatct aattccttta atctattttc tatttttata tgtcttattt catttaaaac
    63721 ttttccacct aatcctacta acttgttatt ttcatcataa aactcaaacc ctaaggcttg
    63781 aagcatacct atcccagcat cattagtagc acttccacct attccaacta taaaatttct
    63841 atagccttta tttattgctt cctttattat ttccccaaca ccataagttg tagtgtataa
    63901 aggatttcta agttcagtcg gaaccaatgt taatcctgat gcttgagcta tttctattat
    63961 tgctgtactt gtatttttta ataatccata tgttgcatcc acttttttag ctattggtcc
    64021 agtaacttct atagtctctt ttttaccatt catcccttga actaaagcat ctactgtccc
    64081 ttcaccacca tcagcaagtg gcaatatctt tacttgcgca tcttctttaa ccttcaatat
    64141 cccctttttt attgcatttc ctgcctctat tgaagataaa cttcctttca aagaatctat
    64201 agaaattaat attttcatat ttatctactc ctttttattt actctttatt ttaaatatat
    64261 aattttataa gcttaattta tcttttattt tatactctat atttcacttt gtatacaact
    64321 tataccctta atattctttt atcttataaa aaagggagtg tctcaaaatg aactttttag
    64381 ttcatgagac actctttttg tataaaatta aatatatgtt tattatttca acaatgataa
    64441 ggaggattat ctctatttta agataattcc tttttagcac tatctaatca tttttagcac
    64501 tatttaacca atatagtttt aacttggttc attaggcact ctacatttac agagttatta
    64561 tctattgata tagattctaa ttctttttca tttaggttag tccatttagc tgttttaata
    64621 tttttgttaa atactacgtt agctgatttt gtttcttctt tagaattgta aaatctaact
    64681 actaatgcct cttctttttc agcctttttt acaacactta acacaaggtc cttattagtt
    64741 tccttaagta aactatatga ataatctact tctatttctg attgattcaa tttcatagca
    64801 ttatatggta ttttattata agtttgtatt tttgttaaat actctttagc catatttgca
    64861 acatttgctt ctagtgtaga tttttcatga gtgactattg ctaagtctat ttttatatct
    64921 cctatcattt gagaatctgg agtaggcaac tttattcctg atggacgacc tgggcgtctt
    64981 gccatttctt ctttacctag gaatcctaca cttctaaata atgttatagc tattgtgtca
    65041 aattttttcc ctactatttc aaactctctt gtactgtttg taagaacagc tactccatgc
    65101 tctttgtcag acaatccaac gaatgttagc attggatata tagaatctgg tctttcactc
    65161 cattcttcct gttgccaaac ttccatagca tcatcataca cacttctctt tatatgtcca
    65221 aactgattat cagacacaga aaactttgaa gctatatttg ttggtatata agttctaacc
    65281 ctacaatctc ttgcttggtt atttatattg aatactacat ttattatagc tttatcattt
    65341 ggaacattta taactatatc aaagtcaata aatgaatctg ctctattatt ttttctagct
    65401 tgtatatctt ttggtacttt taatctataa tttatcttta tctcattatt aaatctattt
    65461 ttctttatag tggaatttgc tactatatta tcgttaaata ttaatttctc atttggaagt
    65521 ggtgaaaaat catactcatc tccttcatct cctccatttt ccatcaataa tacattttca
    65581 aaagttttat ttaatttttt atcagatatc tttaatgtcc cgttttcatt aacttgaata
    65641 gtataaaagt cattatctac catgtcacat acttcataag ctttttctaa catatgttca
    65701 acttctttta tcatatacgc cttatacccc attgcaggta ttttatcttt aaagtttatt
    65761 gtatatacca taaatgaatc atagtttcca taatgaacaa tttgacggtc tattaatcct
    65821 gcatctatta cttctttatg taccacttca aaatccaact tattattatc tttatcaaat
    65881 atttcaaatg ctttcatttt agttataact tgggcgttca ctatttcatt cctattgtaa
    65941 ggcattaagt taaatgctac taacttatct aaagccattt cacaactcat tgcatcaact
    66001 attcttcttt tgtaaaatgt tattaattgg tctacttttt cctcagctaa gaaaaatcta
    66061 ttcattattt cctggtgaac tttatctgaa caacaacatc caatgctgtc atgagcatga
    66121 tttttcatta tttctttcca aattaactct attaatccat gatgatattc aaatcctaga
    66181 gaatatgcaa tagaagctag tggctccaat atgttggtta tctttgattc tattctagca
    66241 tttgctgatt ttatatccat tcttgttgag aatatacttc tatgaaccct catatatttc
    66301 ccatctaaaa attccccttt tattgtatct atatccttat ttttttctag ctctttaaat
    66361 atgttttcat atctacttaa gaaaaatttt ctctctggat aacattcttt taatttatat
    66421 ataacttcaa atatattctt ttgaattggc atttggtcat gtccatttgg aagtattata
    66481 tggtcagtag ttgcaccctt atcaagaacc ggtaaatatt tatccattct tgttcttagc
    66541 tcatcttcat tcattggtag atattttcct attgcataac ctaatggaag tatttgaacc
    66601 aaaacagaag acccatcatc actcttccaa ttaaactctg ttttattagt tccttttctt
    66661 tcagaacatc ctctccaaaa cattgagtat tttatatcaa acccatttag tatttgcggc
    66721 atttgagcac tttgaccaaa tgaatctggt aaatatccta ttttcatata ttctccaaat
    66781 tcatcacaat cttttattcc atacagtaaa tttctaagta tggattctcc accaactacc
    66841 atttcatcag tttgagtata ccaaggacct attattagcc ttccttcttg aactaatttt
    66901 tttattctct ccttacattc aggcttaact gctaaataat cttctaatat agcagtttga
    66961 ccatccatca cataatatgg atagttatga ttattttcta acatatccat tatttcttcc
    67021 atattattta caagtaatat tctagattcc tcagttgaga agtaccattc tctatcccaa
    67081 tgcatatgag gaactatgtg tacatttttt ttcattgctt atcctccaaa acttatctga
    67141 taatattttc tgtctaatta aaaatccaat aaaaatacta ctgagtttac acaatttttt
    67201 aatatttatt ttatcactat aattaaacct ttgatttaaa tatctaataa cgtatctttt
    67261 aatgtatctt tctttgattt ttttgtttcc tagttattat taataatatt gctgatatta
    67321 tagctccaag tactgccgca aagaaccata ttgatgctat aataaatcct gacatacttc
    67381 cctctaaaag cgccaatgag aatatccccg ctccaggcac ttgaagacct atattgaaga
    67441 atgctactat agacccagtt atggctgaac cagctactaa tgatggtata acatggattg
    67501 ggtcctctat cataaatggt attgcacctt cagttattcc agccaatcct aatatccaag
    67561 tttgctttcc tatttccttt tctgattctg aaaataaatc tctgcctaaa acagtagcta
    67621 ttgtaactcc aaaagctgag accatcttaa ctgatgcaaa tattgcataa ggtataaaat
    67681 ttccacttgc tattgctcct attgcaaatg tataggctgc tttatttatt ggtccaccta
    67741 agtcaaatga aaccatagct cctattattg cacctagtag tattgcattt attccagtca
    67801 tcccatttaa ccaatttata agaccattgt taagtgctgc tacaggcttt cctattacaa
    67861 ataacatcaa taaacctact accaaagaac caactactgg atatacccaa aaacttacga
    67921 atccagctaa tgtgcctttg gctggtatat tcttctttaa aaattttact atataaccag
    67981 caagtaaacc tcctaacata cctccaagaa atccactacc tattaaatca gctgctagac
    68041 ctgctgcaaa tcctggtcca agacctggtt tttcagctag tgagtaagac atatatgctg
    68101 ataatactgg aaccatcaat gtacctaaca tccctccaga aagctttctt aattgccata
    68161 accaagaacc ttcttgattg tatagttctt gtaaaccaaa tgcttgagat gctaatactg
    68221 caaatgcaag tatcatacct cctgccacaa taagtggtat tatatgagat actcctgtaa
    68281 gtattgctga ttttacatct tttttccatg atgatttttc acaatatgat atatcagatg
    68341 atttttctat ataatcacct ttaccttgtt tttgtgctac ttctaaagct tcgtatatta
    68401 tttcttttgc cctttttagt ggagctgcta ctgacgtttt tatgtttggc aaatgttcaa
    68461 atctttctgt atttttaggt gctacatctg ttgcatatat tattgcatct gcctttttta
    68521 ttatatctgg tgtatgaggg tccaccatac cattagctcc ttgcttttct acatacacat
    68581 ccacacctat ttctttgcca gctttaatta atgcttctgc tgacatatat gtatgtgcta
    68641 tacctgcagg gcatgctgtt attgctaata caattttttt tgattcattt tgaatcctaa
    68701 tctcttcttt tatttgttct ttcttttctt ttatatctaa gttattaaat aactctttct
    68761 tagtttttga atttaacaac atattcatat aatcttcatt agacagtcta gtaactaact
    68821 cagaaagtat ttgtatgtgt gtatttccac cttcactttc tggtactgct attaaaaata
    68881 ttagctctac tttattattt gagtctacgc tttcccaatt ttctattggt gtctctaagg
    68941 tcatagctgc aaatgcagct tctttaactg acttagattt tccatgagga attgcaagcc
    69001 ctctttcaaa acctgttgga gataaagttt ctctgtacat tacagcttct aaatattcct
    69061 cataagatgt taacttgcct tcatcatata gctttcttgc taagaacttt attgcgtctt
    69121 cctttgtttt tattttttgt tttaaaaaaa caaggttttc atttgtgatt ttcttaaatt
    69181 ccaaaattac gacctcctta aatcatttaa tgttatgaat atagcataaa ataaatcatg
    69241 aaaatgtttt tttgaaatta tacacacaat ttcttcttaa aaaataagga tttgtgtatt
    69301 tatacacaaa tctctatctt aaccagtatt gttctattat tgctctcata atcatcataa
    69361 ttggaacctt atctgatata ttgtacccat ttacttgttt aattgttgaa tagcaatata
    69421 aacttatatc tgcaatttgt tgcaattgat tttcacatat atgtgttaga gctactacct
    69481 tacaaccctt attaactgct gtctttgctg cttctataac ttctttcgtt tctccactta
    69541 aactaagcgc gaaaaacata tcttgttcac ctaattttcc tatatcatga agtacttcat
    69601 gtctttggct atagtaagtt atattatcat gcccacctct aatttctttt actaatatct
    69661 cacataaagg aatgttttga cctattccat aaactataat actcctagat ttttgaatta
    69721 tatctgctac tttatttatt ttttcataat ctattagctc taatgtcttt tttatatctg
    69781 attcaaaacc attttttggc tctttatcct cattttttaa ctcttctttt aaattgtttt
    69841 ttagttgaga gaaaccatca tactccattt ttttacatag cctaactatg gtatttggga
    69901 cagtaaaaaa tttatctgct aaagattgta ttgataattt tactatttct tctttgtttt
    69961 ttctcatata ctcaattatc atgtcttctg tatctgtaaa tttatactca tatttttttg
    70021 ctctttcata aaattccata gtttctcctc catctatttt attattcata agtaaaattc
    70081 aaaaatatta gctaaaattt tcgttaatat aattataatt taatattttt aatttattaa
    70141 tgcatactac tctttttatt atacataaaa aatgtgtact tcctatattg atagagatga
    70201 ttcaggtttt tattttgata catctctatc aatatttttt tagaaaatac acattttttt
    70261 caaatactta tttttaatta aaactttagg taatctattc tttatatata attattagac
    70321 ttgaaaatat ctttaaaatc aaccaattca atattatttc tttttaacca cattttaact
    70381 tccttatcac atagcattgc atgttcatat actctctctt gaataagaga agatgatttt
    70441 ataagactat aatctataaa tcctggatga gtaaccatca atgttatatc tttatctaaa
    70501 tttatatatt tttcttcaaa taatttaaca aaagatttat ttaacttgta aaaatcattc
    70561 tgaggatatt tacttggcat gctaatacat gaatctaaat aatagggaca acttggtata
    70621 ccgtattctt ttgcagcatc acacattgct gatattgata catcttcttc tataccatgt
    70681 atatcaatat actcaggcaa tttactcata tacaacttgt aagtttcaat ttgagcacaa
    70741 acttcttcat atacttcttc ataattaaaa acctctttac ctgtcagtag ttgcgttctt
    70801 cttattttgc tagaaacaaa ttttccacct tcatctaaca aattctttat cttaatatgt
    70861 tctttacaac aaggttctcc tattactaaa ttaacatgta aaccaaaaca tacatcatca
    70921 ttttttacca tttctatagc ttgtcttgaa aaaggcatat tcaccatgat tccagcactt
    70981 gtaacaatac cgttcttata agaagatatt atccctagtg taacaccttc tgaatatcct
    71041 atatcatctg ccctaactac taatttcttc attttatgca tctgcctgct ttctcaactc
    71101 atcaagttgc atttccatct catcctttac tttaacaaca tccgttccta tgatgatttg
    71161 aactgatgta ttactcaatt taattacccc tttggctcct gtttttttaa tattatcatc
    71221 attcaaaata gtggcatcct tcacttctaa acgtaacctc gtcatacaat tattaagagt
    71281 cactatattt tcataaccac cacaattttt aattatctgc ttagccatat atgaaaaatt
    71341 accatgagaa agttttaaat tcttttcttt ttcactaact ttatcaccta tctctatctc
    71401 aacttcatgt cctggtgttt gtacattatc ttttattatt atatatttaa atgttacata
    71461 atataataca aagaatacaa ctcctacagg tataactaac cacgctttat ctccataact
    71521 aaaacttaag acatagtcaa ttatacttgc tccattaaat gaacccaagc gagcacccag
    71581 taaatatagt acaactccac ctagaccaga ataaaaagaa tgaattatat ataactttgg
    71641 agatgcaaat aaaaacgaaa attctattgg ttcagttact gttgccataa aagaagtcaa
    71701 tgctccagcg gtcattgcac cttttacttc ttgcttcttt ttatcttgtg ctgttttata
    71761 tatagcataa gaaatagcag gtattgaaaa catcataatt atgtaaaatc ctgtccagaa
    71821 gaatcctgca tttgggtctc ctgccataaa tctaggaatt tctcctctta taacttctcc
    71881 tgttgatgtt gtatattcac ccatttcaaa taatatgtaa gcatttaaaa cttgatgtaa
    71941 cccagttggt attagtgcac ggttacagaa taaaaacaag aatattccta ttgcaccagc
    72001 tcctcccaac caaaaaccaa attgattcat tgcagcttgt ggatatatcc ataataaact
    72061 aaatatatat gataaaatta aagcaaccac tggtgatagt gtaattacac atttttctcc
    72121 tgcaaagaag cttaaaaatg ctggaacttt aactttatat gttttattgt aagtccatgc
    72181 tatacaagct ccaacaatta tcccaccaaa tacacctgca tttaatgtat cattcaataa
    72241 ctctaaattt gacttaaata tcatatatgc aactacggct gcaaccatta cacttgtctt
    72301 gtctttagac tttgaataag cactaactgc tcctaataaa aataagtagt ccacatttga
    72361 aaatactata ttagatatat tagatatagc tggcacatta agcatatttg gaccaaataa
    72421 taatcctaat atacctgctg ctggcattac agctattggc accagcatag tctttcctaa
    72481 aagtgacagt tgttgcatca ttttgtttaa gaacctcttc atatccaatc ccctttctat
    72541 ttcggtttaa ttttttgtga aaacgattta ttcacatttt atattttaaa tattatattt
    72601 gtttaaacaa attgtcaata ttttttattc attttatttt tatcatttag tttcatatct
    72661 aaatcctttt aagtatattg ctatatctag cctatttttt aaatttattt tttttatttt
    72721 taaaatatgt ttaaccatgt atttgaaaca acccacaaaa tagttcaaat ttatcctttt
    72781 tatggtttat ataattctat tttcactata catgtctaaa cacatttgat ataatttgtt
    72841 catatcagtt caataatatt actaaagacc tttaaggagg gataggggta tatggctaaa
    72901 aataaatttt cagagatata tgaagtattg aaagaggaaa tacttgatgg taaatataca
    72961 agtaatatga tgctgcctac tgaacttcaa cttattgaaa ggttttcatg tagcagaaac
    73021 actgtacgta gagcaatttc tcaattaaac acagaaggat atgttcaaag tataaaaggc
    73081 aagggtgttg tagtgttaga aaatagttgt tctaatgatt tttttctaaa tatgcacaat
    73141 ttcaaaggtg tagaatcgat tgtagaagat aaaaaggtta atactgctac tagtgttctc
    73201 cacttcagca aaatcttaat tgataataag ttatctaaaa agacaggttt taaagttggt
    73261 agtgaagtat attaccttca cagactaaga tatattgata acatacctaa aattctcgac
    73321 attaactatt ttctatgtag tatagttaaa gaccttgatg tttctatagc acaaggctct
    73381 atttataaat atatagaaga gtgtataggt acaaaaattg tttcatccag aaagatattt
    73441 aaaattgaaa aagctacaga gcttgagtta aaaacgctac ctctaaatga ttataattgt
    73501 gttggtgtta ttaaaaatag tgtatatact gatgatggaa agctctttga atatacagaa
    73561 tcaaagcata cacctgaaac atttgtattc atggatgtta ctcaaagata ttaaaaaaat
    73621 tatgtttaat taaacataat ttttttacgt ttagacactt tatcccatac taacctcact
    73681 attctatata caattatatg tttatacaaa taattattta ttgtatattt tagctttaat
    73741 attagtttaa tacttgacaa tttgtttaaa catattataa ttaacttata aattacagga
    73801 ggtatcaatt atgaaaaatt ggtggaaaaa agcaactgtc tatcaaatat atccaaaaag
    73861 tttcaaagat agcaacaatg atggtatagg tgatataaat ggtattatag aaaaattaga
    73921 ttatctgtat tctttaggtg ttgatttatt atggttgact cctatgtacg tttctcctca
    73981 aagagataat ggatatgata tagaagatta ttataatata gacccaaaat atgggacaat
    74041 gagtgacttt gaaaaactct taaaagaagc tcataaaaga gacataaaaa taatgatgga
    74101 tatggtccta aaccatacat ctactgaaca taaatggttt aaagaatcta aaaaaagcaa
    74161 agacaatcca tatcgtgatt attatttctg gaaagatgct aaacctgatg gttctgttcc
    74221 taataactgg atatccagat ttagtggaac tgcttggaaa tatgatgaaa ctactaacca
    74281 atattattta catttatttg aagaaactca agctgattta aatttggaaa atgaaaaggt
    74341 tcgtgaagaa tgttacaaag tactagaatt ttgggctgat aaaggtattg atggttttcg
    74401 tttagatgta gtcaacctac tctccaaaac acctggatta cctgatgacc ctataacagg
    74461 gccaaaagga gatggaagaa ctcattacgc tgatggtcct cgtatacacg aatatttaca
    74521 taatatgaat caaaaagttt tcaaacctaa aaatatagtt actgtaggtg aaatgtcatc
    74581 tactacacct gaagagtgta tcaactatac tagagaaaat cgagaagaac tatctatggt
    74641 ttttagcttc catcatatga aaacagatta taaaggaggc gcaaaatgga ctaatgaaat
    74701 gttctctctg gataaattaa aaaaagcaca atctgacttt caatataaaa tgtatgaagg
    74761 aaagggatgg aatgctctat tttactctaa tcacgaccaa cctagagctt tatctcgatt
    74821 tggagatgat agattttttc gtcaagaaag tgctaagatg ttagccataa cactatttgg
    74881 tctacaaggt actacataca tatatcaagg tgaagaaata ggtatgacaa atgcctactt
    74941 tactaaaata gatgaatatg atgatgctga aagtaagaat gcatactatc atatgattaa
    75001 atctggtatt gatgaaaagg aggcattgct tatacttcaa caaaaatcca gagataatgc
    75061 ccgtactcct atgcaatggg ataatactat ttataagggg ttttctaatc ataaaccgtg
    75121 gttaaaagtt aataatgaca atattagtgt agaaaatgag cttaatgatt ctcgttcagt
    75181 attttatact tatcaaagat taatcaaata tcgtaaacaa tatgatattt ttacagaagg
    75241 tacttataga ttgttagatg aaaatcataa aaatctattt gtttatgaaa gagagtataa
    75301 aaaccaaaat cttcttgtta taagtaattt tactcatgat aatgtagtat ataaattacc
    75361 tgaaacttat ttgaataaat taaactacac aatacttgaa accaattaca ctagagatat
    75421 aattgaaaat aaaatggaaa taaaacctta cgaaagtata atgatatatt ataaataaag
    75481 ttatttatat aaaaattggt ataacaccag ggtgttatac caattttact aaattcaaaa
    75541 taacatttat agaatatcta tagattacaa taattatttg acttctacat cattatattt
    75601 ctttgaatat actttagtca tatagaaata tataggaact acaattatca tcccacctaa
    75661 tccccaaact atcttcatag gttcatcaat acctgctttt atcagtaata atatacttat
    75721 aataactgca aatattggta taattgctcc tccaggtatt ctaaaattta catctttatc
    75781 agcatacttc tttctcaata ttagtacagc taaacatgta ggaatatatt gaataaatct
    75841 agatacaaca cttatttgag ataatgttgt gaatgaaccc gaccatgcta ttagtaaagt
    75901 tcctatgaca gatactataa ttgctatata aggagctcca tttttattag tttttcttat
    75961 agacttaggc attaatcctt gttcaaccaa agcagcagca gaccttggtg taaatatgga
    76021 tgatgcaata tttatacctc caacagatac tatagttcct attgtaatta tatacccacc
    76081 tataggacct agcatcttaa tggcagcatc tgcaacagga gtagctgacc ctgccaagcc
    76141 attacccaac acccctatac ttattcccag tataagcata tatattactg atactacaaa
    76201 cattaccatt accaatgctt taggtacatt tttcttaggg ttctccatat cttttgctgc
    76261 aacagctaaa gattcaaatc ctgtaaaagc ataaaataaa gttatagata ctgctacaaa
    76321 agctgatgac gcactttgac ccttttgtat tattacaaat ggggtaaaat tagaaccctt
    76381 tataaagaat aatcctacag ctataaataa aactattggt aataattttc ctatagtcat
    76441 gatattattt aagtgcttag attgtttcat tcccataaaa tttataatcc caagtcctac
    76501 aactaatata ccaattatta tatttttaat aagtggttct gctgcttgtg gccatacaga
    76561 tgatagtgtt acagcaaaaa aatttgccat agtagcccaa gcaatcatac taactatcca
    76621 cttcataaat ccaacttcaa atccaacaaa atctccaaat gcctcttttg cataaagata
    76681 aggccctcca tcagtatcaa accaactacc tgcttcagca aaacataaag caatagaaac
    76741 agctaaaagc atacaaaaaa ctaatactaa tatacttgct ggacctatat ctgtataagc
    76801 atcaccaggt aacccgaata tacctgaccc tattattgca ttgattccta atagtacaat
    76861 actccaaaaa cctaacttaa tgcctttttc cattgttatt ccccccaaag ccaacttaat
    76921 atatttatat tttttattta gatgcttctt taactattgc cataaatatt tttttcatat
    76981 tatcataatc tctagtcatc atttctggat gccattgtat ccctattaca aactcacttc
    77041 cttccttttc tatagcttca attaaaccgt ctttagatgt agctgaaaca atatatcctg
    77101 gtgctacttt gttgacaact aagtgatgaa aactattaac taaaacttct ttttctccta
    77161 atatttcata taattttgtc ccctccttta tctgtactgt atgtgtaggt acattagata
    77221 gatgttgctg attgtgttta atataagcac cttcaattaa agataaatct tgatacaaac
    77281 tacctccttc agttacattt ataatttgtt ctcctctaca tatacctaaa actggttttt
    77341 tcatatctaa agcatgtttt aataatttca tatcaaaact atctctcttt ggtgatattg
    77401 cccccaactt attatgaggt tcttctttcc atatgagtgg atttacatct tgtcccccag
    77461 atagtataag cgcatctata ttagatacct gctcctttat aatctcatca tcatatacaa
    77521 tcggtacaat atatggtata gctttacaca taactactga ttgtatataa tcattattta
    77581 cataagccct ttcatagcca ggaaacattc ctccttcatc aattagtaaa ttacctgata
    77641 ttcctattat tggatatttc tttttaacca atttcttcac cccttaactt atttgtgaac
    77701 aataaaaaat gctacttctc ttaaagagca agtagcatac caagatttta tttatttgaa
    77761 cattataatt cattttagaa atactttttt tgaatacaag taatataaat aactttattt
    77821 acttatattt tattttaatc ctgtttagtt tgactttttt aaattgtttt aagtacaact
    77881 aataggtaaa ataggcattt agattttcct ttttatcaac ctattaaata ctgtttaata
    77941 tattttttcc ccttctattt aattcacttc cctttctacc agattcacat attatcaaat
    78001 ccagctcttt taacatatta agtattcccc ttacctcacc ttctgttata ctgtagccta
    78061 attcatttat tgaattaaca ataccatttc tacctatatt tttattaaga ttattggcat
    78121 tttttaaaca ctccattact aactttactt tctctataga tgttctatcc tttaatatgc
    78181 ttatttcttt actaaaatct tcagttatat ttaataagtt atgaggtaaa tcatttatta
    78241 aaataacatc ctcagaactc ataatgttaa tatacatagc agtatttttt aattctctta
    78301 tattacctgg ccattcatat gcattaataa tgtcttgaac accttgacta attgctctct
    78361 tccttttcat aaaatgcttt aacataactt ctatatcttc ttttcgctct cttaaaggtg
    78421 gtatatttat gggcaataca tttatcctat agtataaatc tgctctaaat ctatctcctt
    78481 ttatcatttc taataaattt ttatttgtag ccgcaattac tctaacatct atatctatta
    78541 cattttctcc tccaaccctc attacttgat tctcttgtaa tactctaagt aatttgcttt
    78601 gtaagtatat aggcatgtct cctatttcat ccaaaaatat agttccattg ttagcctgtt
    78661 caaataatcc ttttttacct ccttttaaag ctcctgtaaa agcaccttct tcatatccaa
    78721 aaagttcact ttcaagtaaa ttttctggca tagctgcaca gtttatcgct ataaatgact
    78781 gactatgtct tggtgatgca ttatgaatag actgagccat aagttctttt cctgttccac
    78841 tttctcccgt tataagaatt gtataatcag attcagctat tttcatacct aatttcttag
    78901 ttctttccat cttcgttgaa actgttttta tatcatcaaa agtatatcta gcaacttgtc
    78961 ccttttctct aagcttcttt gataggtttt gctccaattt tcttatataa gttatttctt
    79021 gaatacaaaa ataataccca gtaacccttc caaaactctc tatattatac ttatttacgt
    79081 ttaagtactt attattaaat tttataactt catcatgtgc cttactcaaa ctaaaaatct
    79141 ttttaatatt ctcattctct aattcatcta tatttttccc tataatatta ctttgaatat
    79201 ctagtatatc ccttaaacta ttattgcaaa taattatgtt tcccttatct gataccattg
    79261 ccatacctaa gtttgataaa tttattatag aatttaattc atctgctttt atagtaagtt
    79321 ctttgtattt agtatttatt cctgaatata aactaattat ttcatctgta tacttaatta
    79381 gcctctcagt aatttcttta tcatccagtt tgagttttgc tattatttga ataaacgttg
    79441 aactatcaat atacctatgg cctaaatcaa taacttcttc tatatatttt ggaactaaac
    79501 ttgactctcc tggcgttata gctatcttaa tatttctata ttcttcattg ggattgtatg
    79561 gtataaaatt caaatggttt attcctatat tgtataaatt agatattgtt tccaatacag
    79621 tatgcttatt atcgtttact actaatacat ctatttcttc tggcaatgaa aataacttat
    79681 atatatcctt ttgctttatg ctcctattta tagttattat ctttgagaca tcttctacat
    79741 atttttttat ttttaatact ctatcatcta tcattaccaa tattatgtca tcttttatta
    79801 attccttctc tgttatttta tttaaataat aattttttat cattacttta tctttaaata
    79861 tcatttctag atttttattt aagaaacatt ctaatttaga caacccatca gttactactg
    79921 ctattgtttt catttgatta ctccttttaa aatatactct actcttttat aatatacatc
    79981 tgattttcac tttaatagca caaaaaattg tacatttagt atactaacat attcctttat
    80041 tagttttatg tccctaaata tcatagttgc aatatctatc atatttctta aacttctata
    80101 aagcaaaaat tgtgccaaat taataatttt cttaatttta ttctaaagtt cctcaatagt
    80161 atttacagac ttagcactta tagcttataa gtctttatat tattaatcta tttttatagg
    80221 ttaattgtac aaatcatata tcacttttac ctattaaatg cattataaaa aagatggaat
    80281 aacgattcgt cactccacct tttttgtaat aaaaaattgt atatataaac actatttact
    80341 actcttctaa gtacaaacag tatctacata ctataacctt tcaccattag attctattac
    80401 ttgtttatac cagtcaaaac tctttttctt aatcctagac aagtctccac ttccatcatc
    80461 atacttatcc acgtatataa acccatatct cttggtcatc tcaccagtag atgcacttac
    80521 taaatctata catccccatg gagtatatcc aaataaatca acaccatctt ctacagcttc
    80581 cttcatttgc tctatatgtg cttttaaata ctctatacga tagtcatcat ttatcactcc
    80641 attagattct tttttatcat aagctcctaa accattttca actaccatca taggtattct
    80701 atatctatca taaatttcat ttagtgcata tctaagccct tcagggtcta tttgccatcc
    80761 ccattcacta gacttaagat atggattttt cactccacct aatatgttgc cacttgtatt
    80821 atcttcttta gaatcactac ttacacatgt agacatataa taactaaatg tataaaaatc
    80881 tacacaacct tcttttaaaa tttctaaatc tcctttttcc atttttattt caatattatt
    80941 ttctccaaaa tatctattca tataagttgg atattcgcca cgcacttgta catctccaca
    81001 gaaataattc attactctac tatctctttg agttttaact gcatcatctg gattacaagt
    81061 ataaggatac attgttgcaa atatttgcat acatccaact tgataatttg aatctatttc
    81121 atgagctaat ttaacagcct tagcacttgc tacaaattga tgatgtaacc cttgaaaacg
    81181 aagttgaggt atatctactt ggtttataaa atctgtagtc ccttcattta atattccttg
    81241 tgataagtag cctcccatag gcattgtagc tgaatttatt tcattaaatg tcagccaata
    81301 ttttactttt cctttatatc ttttaaatat tgtttcacag taattcatat acaagtctat
    81361 tacctctctt gaaacccatc cattgtattt ctctgttatt gcaaatggta tttcatagtg
    81421 agatattgtt attaatggtt ctatattata ttttaaacat tcatctatca cattttcata
    81481 aaatttaagt cctgcttcat ttggttcttt ctccattcca gttggaaata ttctagtcca
    81541 tgctattgaa aatctaaata ccttaaatcc catttctgca aataaagcta tatcttcttt
    81601 gtatctgtga taaaaatcta ttgcttcatg acttggatag aatgttcctt tttctataac
    81661 tctcgttatt cttttactta ctttttgaga acccccagta cacatatctg aacaagaagg
    81721 acctttccca tctaaattcc atgctccttc acattgattt gctgctgttg ctccacccca
    81781 taaaaaatct tttctaagta ccattactct acctccaata atttatttat agtaaattta
    81841 ttttaaaata aaaatacata tatctaattt ttaattaata aaactctctt ttaagctaaa
    81901 acagttatca attcctgact attatttaca tgcttttgtg tattttctat aatatccaca
    81961 taatcagaat aattagtaac aactactggt gtttctaagc aatatccttc ttttgatatg
    82021 ctttctatat caaaagttat taatgtctga ccttttttaa tcttatcccc ttgattaaca
    82081 aaagatttga aatgtttacc ttccaactga atagtattta accctatatg tatcaatagt
    82141 tcacaaccat tatcagatat aattcctatt gcatgttttg ttggaaataa agtcattata
    82201 gtcccatcaa atggtgccac tacttttcct tctttaggtg ttattgctac accttttccc
    82261 aatatacctg ttgaaaacgc tgcatcttgt atctgctcca aagcctttac ttcacctttt
    82321 attgggctat atactacttc tcttttgttt ttttctacaa cgccttgccc attattatct
    82381 ttagaaattt ctactataga atcatctttc caaaaaaata atgttaaaac aaatcctact
    82441 acaatagcta ctattattgc tattatagtt gcataaacac ctttcatatc tccagttgtt
    82501 ggatttatat aattaggtat accaaatatt ccaagtccac ccattacata actttttaca
    82561 ttcattatcc ccattacagc tcctgccaca gcaccaccta cacaactata tatgaatggt
    82621 gtttttcttg gtaaagttat tccatatatt gcaggctcta ttacaccaca tatccctgaa
    82681 ataactgcag gtatacacag ctcttttatc ttcttatctt ttaatttaaa gtacattgct
    82741 gctactactg atgtttgtgc aaaagatggt acaaatgctc ccactaatat tgtgtcaaac
    82801 cccatagtca taaggtttga catagctatt ggtactaatc cccaatgtag accaaatatt
    82861 acaagcactt gccacaataa accagttaat acaccacata aaattggtga aaagttaaat
    82921 aaagctaaaa atccatttcc aactatatta gaagcatagg tagctatagg ccctataacc
    82981 ataaatccca atggtaaaga aactaataaa actgccattg gtacaaagaa attctttact
    83041 acatctggta ttattttagc aaacactttc tccaacttag ctgctaataa tactattata
    83101 attactggta ctactgttga agtgtagttc attgctatta ctggtaatcc taagaaagtt
    83161 atatatactg gtgattcaaa tattgttcca gtaaatagat tgtataaagg ttgacctata
    83221 gatgctagag tatctaattg aatacctgaa tagcataaaa ctgcacctat aagcattcca
    83281 ataaatggtt ttaatttgaa tttcttagca gctgtatatc caagaattat tggcatatac
    83341 tggaacattg catctccgat tgcatttaac ataatatatg caccatcagt ttctccatac
    83401 aaacccaatg ctgtaaatac tgcattaaat ccttttatca taccagcagc acacagaact
    83461 cctaatattg gttgaaaaac tcctgatatt atgtctataa acttattaag taatcctttt
    83521 ggcgcatctg aatctgaatt atctattgta tctcctccta atccagccaa atcgcacaca
    83581 acttcataaa catctggaac atgattacca ataactactt ggtattgacc tgcacttttc
    83641 attacagtaa ctataccatc catttttttt agcacatcat catttgctat tgattcatct
    83701 tttaatttaa aacgtagcct cgttatacag tgagataaac tgctaatatt atccttccct
    83761 cctacattct caatgatttc ttttgatagt tgttcatatc ttctcatttt ttctcctcca
    83821 ttttcttttt gaaatatgaa ggtttggcca acttaatgtc accacccaat atatataaac
    83881 ctaattatta ggatttatat ctgacttaat acttttactt accactcttt caacgtgaat
    83941 agttaagtat aatttttcct catctgttaa atcgtagttg tattttttat gtataaattc
    84001 atccaacttt tctatgcatt tataagcatt tttatattta acttttatta catttagtaa
    84061 atcatcttca ttattttcat gtaaattatt actaacaatt cgttctgcaa aatactttaa
    84121 gtgagtaata aatctatgat aataaactga atcttcatca aatactattc tgtaatggta
    84181 tttaaccata tttgaaattt cttgtattat ttgtgtaatc tcatatatag tttttatact
    84241 ttgatccatt tgtgcattaa ctatatgcag tgctataaat ccagcttcat cttctgatag
    84301 tctaatttca aatttttttt ctatataatc caatgcttct aaccctattt taaattcact
    84361 cttataaaat ctttttatat cccaaagtaa tacatttttt acacttactc cttcacgagc
    84421 tctttctatt gcagtataca tatggtctgt taaagaaata taaatactat catttaatct
    84481 tttccctagt ttttctttag catataaaat tatttcatct gataattcca tatatcttat
    84541 aggaatatct gctattagtt ctttaaattt atcagatata tttgggtctg aaagtttgaa
    84601 tatcttatca attttatcct ttgatatatg ctctcctgta cgttttttat aagctaaacc
    84661 tctccccata actactattt ccttatgatt ttcatcagtt gtaataatta cattattatt
    84721 gagtattttt tcaataatca ttgtgatgcc ccctttatta gcattaagtt aaaataaatc
    84781 ttttttaatt atttagaata tttaaaatgt aatttattac ataaaaaaaa acctatttat
    84841 tacacattaa atagactccc atgagtcctg agtaataaat aggtttagct tgtatttaaa
    84901 caatcactat ccgtttgtat tttattttaa ttattattta ttatatgtta gcaaatttat
    84961 tttttagtgt caactttttc tcaatatttt aattctaaat aaattatata aattgcatct
    85021 gcaaagtact atttttataa ataaacaaaa taaaaaaggt attacttgct ttaagtaata
    85081 cccatttatt tttaatttaa gtggtttttc ttaatctcat caagtagtcc atcttctaaa
    85141 taaatttcta atgcacatcc taccattgcc tttactgctt tgtgaagttt atcataagct
    85201 tcctcagaat ttgcataatt tagaaattct ttttcatgaa catataccat tggacttata
    85261 tctaaggcta tttctgtata catagtaggg caaacttgac ttacattacc tatatctgta
    85321 gaacctactg gaccatcttt accttctaat atatctgtta tacctgactc aatcaaatta
    85381 ttctttgtta tcttttgaag tactttgtta tttattatgt tgtcaaaaga attttcaaag
    85441 tatctataag aaagcttagc tcctgtcatt aactctgcac cttttgcaca gtttataact
    85501 tttttagtca cttcatctaa ataacttctt tcagcagctc ttacaaaaaa cttacaagct
    85561 gctttttctg gaactatatt tggagcctct cctccatttg aaactattcc atgtattcta
    85621 acatctgatt ttacatgttg tcttagtgca tttatcccag caaaagtaag ttgtactgca
    85681 tctagtgcat taactcccat atgagggtga ctagctgcat gtgctgatac cccttcaaaa
    85741 ctaaactcta atgaatctat tgccaaagcc ttacagttta tattattaaa agcttctata
    85801 tgcatttgat aacttacatc aacatcatca aaagctcctg ccttaactaa atcacatttt
    85861 cctcctgttg tttcttcagc tggtgttcct attagtacaa tttttccttt aaaattttct
    85921 tttaacttac ttaatactat acaagctcct agtgtagatg ctgcaatcca gttatgccca
    85981 caagcatgag ctggttcttt attgtctcca tatccaggaa gtgcatcata ctcagctaaa
    86041 aatgctatgg taggtccatc attatctcct aattcagctc taaaagcagt ctccatatta
    86101 caatatggat aaactgtatc aaatccatat tccttcattt tctctactaa gtattttgat
    86161 gatatgtatt cttcttcccc taattctgga ttgttaaata taaaattaca aacttcttca
    86221 atttcttttc caagttcatt ctctatctca taagctctct tctttatact ctctatcata
    86281 acttacctcc cactagaatc ctagatataa tcctattgtc aaaaatacca ttacaagaat
    86341 tgttaatact accattaaag gaattacgaa tctaacccac tttgaccaag gaatattggc
    86401 tactgctagt gctcccatta aaacacctga tgtaggtgtt attaagttag ttacacctat
    86461 accaaattga taagctgtaa ctatcatttg tcttgataca tctactaagt cgccaagtgg
    86521 tgcaagtaca ggtattgtaa gtgatgcaag ccctgatgct gatggtatta aaaatgctat
    86581 taatccttct attaagaaag ttaaatttat aaatatagtt tttggtaatc catttaataa
    86641 atttgctgca gaatttaaaa ttgtatctat tataaatcca ttttctgcta ttattacgat
    86701 tccacgtgca aatgctatac ataaccctgc tgtaattaaa tctcctgctc cacttataaa
    86761 tgaattaact atctcatctt gtttaagccc tgatgctatt cctgatatta tacctatagc
    86821 tgtaaatatc attgcaattt cagttatgta ccactctagt cttaaaactc catatatcat
    86881 aatcgccata cctattgtga aaatggctat taccatggct tctctttttg taaattcctt
    86941 tatatttgta tcactattaa ccattgattc ttgatttagt gatatatcgt gtactaaaga
    87001 ttttttaggg tcttttttaa ctttattggc atacatcata acaaatccta tagatatagc
    87061 catatatatt ataaacataa caactctaaa ctctattcca gaacctggta ctatttgtga
    87121 taatgcttgt gctattccta cagagaaagg attcgtagta gctgctccaa atccagctgt
    87181 tgctcctata aatactgtgg ccactgctgt caatgaatca tatcccatac tggtcataag
    87241 tggaataaat atcatataaa aaggtagtgt ctcttcactc attccaaacg tcgtcccacc
    87301 tagtccaaat agaatcattg aaatcggtat tattaaaaat tgaaacttct tcattttatt
    87361 tacagtatga gctataacag cttctatagc ccctgtttta ttaactatcc caaaagctcc
    87421 tccaactatt aaaacaaatc caactacttc agctgcatct ataaatccgt ttataggtgc
    87481 tgtaaataca tcagtaattc cttgtggatt tgatggtgct ttttcataag ttccagctac
    87541 aacaactgac cttccgtcta tatctactct ttcaaaattt ccacttggca ctatccaagt
    87601 aagaattgcc attaacacta ttagcgaaaa tattattgta agtgtctgtg gcatagtaaa
    87661 ctttttcttt tttaaactgc tcatttttaa tctccccact ttttaaatta aatattttat
    87721 tattgcatcc ctttatccta ttttgtatag atgtaaaaaa gctcaacatg gatacatgtt
    87781 gagctaaatg tgctaaatac aacatacctg catcttccct ttatcttgtt taagatagct
    87841 ctccatcaaa attcgggata attttgatga cagtactgta cctattaaat acagtcccag
    87901 cactagcttt ggacactagc acttcggcac ttactccttt tatattgcct cattggtttc
    87961 caacctcttc aatattaatc ttagtaaatg caacctctac ctcaatctgt tcgttagatg
    88021 aggtaattct tattaatttt tattgattca aagtaattgt agcataatat gtcgagattg
    88081 taaatatttt cagtataata attcttactt tatgatgtca ttccattttt cacaaataat
    88141 tttttctcca tataatttaa atactgtagt atattttaaa tacacacaaa ctttccacaa
    88201 atttttaatt attataatac ctttataata aaaaataaaa gccatgtaaa cttatcaatt
    88261 tacacagctt tatatacatt aatctactcc aagtacagct ttaagctttg atgctattgt
    88321 aataactcgt ggaccaaata taacttgaac tgagtttttc tttttaacaa ctccacttgc
    88381 acccaattca tttacccaga aaccatcttc atagaatcca tcaattgaat ttagctctac
    88441 cctaagtcta gttgcacagt ttgtaacatt ttttatatta ttacttcctc ctaaaccttc
    88501 tattatagaa tgtacaagct ttgtatcttt atcatctact tcctcttcta ctgcattgtt
    88561 gtatgctgtt ttaccagcat ctacagattg tctttctcta tattctttct tactataaag
    88621 cttaacttct tctgaacttc ttcctggtgt ttttatatca aacttcttaa ttgcccatgt
    88681 aaatattata taagtaacta taaaaaatat tggtatcaaa aataataatg gtaacgcatc
    88741 cactttttgt ggttgtaata aattaggaaa catatttcta aatgattctc ccattataga
    88801 aacattaaac atttctgtaa atacatacgt caatcctgcc agtggtacat atgctacaaa
    88861 atacaataat ggtgcaacaa ataggaatgt atactctatt ggttccgtta cccctaccaa
    88921 catggctgtt actattgctg gtatcaatat acttattgct tttttcttat tagcattatc
    88981 agccaactta tacatagcta aagctgctgc tggtaatatt gcaaaatgta ttaataaacg
    89041 acctgttgtg aagttacgag ttatataaga tagtgtatct gggtctccca tttgagctaa
    89101 tcttatatta ttaacaccct cgtaaattgc tccacctact tccattgttc cacctactct
    89161 tgtatattct atagggaatg caattaagtg atgtatacca aatggtaata atgctttatc
    89221 cattgctcca aaagtaaatg ttcctaataa tccactagaa cctatccaat taccaagttt
    89281 agataatgcc aaccctactg gtggccatat aaagtacatt gctgtaccca atactattga
    89341 tgctataaac atcataatca ttgaaaatct tggacctgag aaaaaagata atgcactagg
    89401 aagttctatg tcaacaaatt tgttatgtac tgcactagct acaaatccag ctattatagc
    89461 tccaaatata ctacaatcat atgaaaagat tcctaagaaa gaaccatata aagaacttcg
    89521 actatatgct tctgcctctc ctaatccaga tgccataaac gcttctgctg taactgtatc
    89581 tgaatttata ccatttgatg ctaacaatgt acttataact gtgtgcattc ctataaataa
    89641 aacaattcct cctaatgcac cccatccttt ttccttttta gataatccaa aagctatacc
    89701 tgtaacaaag aatattggta agtatctcat taccataaat cctaaatcgt ttattacttt
    89761 aaagaataca tttataaatg acccttcttt tattagtccg ctaagcccta atgcagaaac
    89821 gttttccata tttgcaaaag ctgaccctaa tcctataaat actcctgcta caacaagtaa
    89881 tataacaggt atcatcattg ctccagaaag tacttgtaat ttatccttca tagtattatt
    89941 tcctccattt ttattgaaat gccaggctat ataatgcata tatatatact tctattgctt
    90001 tgtataatgt atctatactt atattttcat ttgcctgatg tgaatttgga ttatctccct
    90061 ctattgtggg tccaaatgca actccatttt ttaacactct tgcataagat gcagctcctt
    90121 ttgtaaaaag ttcggcttct tttccaaaac cttgtttata tgcacttgat aatttattta
    90181 ttaattcact atctggtttt acatacagta attttaaatc cttatatata tcaactatta
    90241 aattttcttt tttcccaatt tcattaattc tattagttat aaactcccaa cttataccct
    90301 taggatatct aaagtctatt ttcatattca attcattttt ctctaagaag atactcatta
    90361 tacatattgt agaaactccc atatctacat cttctttata tatccctaat ttttttccat
    90421 gattatcatc tgtaaagtat gaatttaaaa tatcccttat tataacgcct ttatcattta
    90481 gctttttaat tttctctaaa tcttttgcta aactaaatgc acagttatat gacctgtgtg
    90541 gatttctcga taaagccctt tctcctgtat atcttactaa tactttacct tcttctagtt
    90601 cttctatctc tgtataataa gctaatgatt ctactaaatc tttcttatca tcagttttaa
    90661 aaacagcctc aattttgtca catacaaatc catcttcttt gtttgacttt atatcaacta
    90721 aattgtgatt tctaaattta tctttatcta ttttctttct tagattgaag tataaaatac
    90781 cattttctcc atttactatt gggaagtttc catctggaga aaatgcaaat tttggctgtt
    90841 cattgacact aaagtaatgc tccatacatt cccaagtcgt ctcttcagct ccacccacta
    90901 tcaatctaat ctttctcttc ggcttttcat taagttctct taagaaaagt aatgcatata
    90961 aaatccctat caaaggtcct ttgttatcat taactcctct accataaaga tagttatctt
    91021 tttgacatac tttaaaaggt ttactcttcc aaagttcttt attatatatt ggcaccacat
    91081 ctatatgatt aagcacccct actacttctt ctccttctcc atattctata tgaattgcat
    91141 atccatcaaa gtcttttaca acaaaatctt tgtcttttgc tatttgaata agcttatcga
    91201 aggcatttct tatttctatc ccaaatggtt gatttatatc tgttgtactt tcatctctaa
    91261 ttgaaggtat ttcaactaaa cttctaatat cctttatgat attttcttga ttggatttta
    91321 aataatcaat aattagttct ttgtttacta tcatcttaat tatttatcac ccctttatat
    91381 taattttaca aagcatttca gttcatatct acattataaa ttttgaatat tattttttca
    91441 atatttcaaa tacttctcta aattaccata atgatacggt aaacaatcaa cagattatga
    91501 caaaatcata ctatacctat tactaatatt ttaacttatc tattacgtct tttttaatgt
    91561 aattttattc caaaaataga tataaaaaga tgtagcctta gctacatctt tttatatcta
    91621 ttcaacttcc attattatgc tattaatatc tacatttcca ggttctatcc tatcttttac
    91681 tgttctctta acagaatcag catcatccat tataactaca ggagttatta tatttaaatc
    91741 atttgacgtt ataaaatcta aatctacttc cattattaaa tctttagctt ttaccttatc
    91801 tcctgccttt accttaacat caaacggctt tccttctagt gacattgtct ctaaacctac
    91861 atgtattaat atatttgtat tatcattact cttaatcatt attgcatgct ttgtatcaaa
    91921 tacattgact atttcaccat caacaggaga atataactta ccttcatttg gtattattgc
    91981 tactccatct cccatcatct tttgggcaaa aactgcatct ggaacatctt ctaagttcac
    92041 taaatttccc ttaaaagggc tatatatttt ctcaatctta ttttcttttt tcttaaatat
    92101 attaaacata acacactctc catattataa aattttatga taatattttt cttaaagctt
    92161 ttgctacacc atcatttaca ttagtatcag ttacaaaatc tgccatagat tttacttcat
    92221 ctgtagcatt tcccatagca ataccaagac ctgcaaattt aatcatggat atatcatttt
    92281 cattatcacc tatacaaata acttctttgc tatctatacc taatatatca caaaattttt
    92341 taactgcaat accttttgaa gtacctttac tcataacttc aaaatttatc tttccagaac
    92401 ttactacttc taaatcttct tgttttttaa attcttcctt tgcttctctc aaagaatcta
    92461 cgttttctga gaaaagtata cattttaaaa tttcattatc agctttttct aataaagttt
    92521 cacaacttgc attttctatt atttcaattc tgtcttcttc tttattttta ctatttatta
    92581 atctatatgg atgttcttca cctatttcat tgttggatat aactatttta cagcctttaa
    92641 aatgtttgtt taaattatac ttttcaccta ttgtatagat tttctttata gcttctttgc
    92701 tcaaaacctt cttatactca tatcccatta atttaaaata tgtcccatta gttgatataa
    92761 tatatatatc atcccctaaa acacttgtaa aatatttcat agcattataa ggtcttcccg
    92821 taactaaggc taccttgata cccttttcca tagcttcttt tagtgcttta atattttctt
    92881 ctgatacttc aaatcctttc cccatcaaag taccatccat atcagtacaa attaatttat
    92941 atcgcatttg tatcacatcc tagtaagatt tttctaatat ttcaacaagg tcttctttct
    93001 ttccaaaagg taaaaatcct aaaactggac agcttgttat ttgttctaat tgttcctttg
    93061 ttacattaaa ctcagacatt tttgtcttaa gtcccactct ctttaaaaaa ctttctattt
    93121 catttcctaa agttttagct gcttcatcat cttccacttt ttctaattct tggtttagca
    93181 ttctcgctac tttggcaaat ttctctatat tatccttata gaacttttct gcaaattttg
    93241 ggaacactat agccaaagcc tcaccatgag gaatatgtgt aactcctcct attatttcac
    93301 ttagtggatg tggtgctgct gctccagcat ttgccagtga acttcctcct aatgtatctg
    93361 ctactgctaa ctttgttctg tattctatat tatttttatc ttccattact ttaggtagat
    93421 agttaatgac taattccata gatttttcag acattatctc tgtaaagtca ttagcatttg
    93481 gatttatata actttcaaat gcatgagtaa aagcatcaaa tgctgttgat gcagtaattc
    93541 tctctggcag agttaacata agctctgggt caactataca ttcttttgag aaacaatttt
    93601 gatgaaatat tgtatttttc tcgcttcctc tcgatattac tgctgcttgt gtaacttggc
    93661 ttcctgttcc agaagtagtt gatacagcta ttaatggtaa ttctttttca cttaccttat
    93721 cgtatatttt aaatggattt gtatatgtac taaacatata atcccaatct attttttcta
    93781 aaccaaaagt caatgctaat acttttgcag tatctatact tgaacctcct ccaacagcta
    93841 aaacaacatc tacagattct tttttagcta attcgaaccc ttcatttatt aattctacag
    93901 ttgggtttgg ctctactcta tcaaagtgta caacttctat acctttttct attaaattca
    93961 atgtaactct tttatataac ttgtctaatg gctctacatt tggagtagta actaacaaac
    94021 atttctttcc atattttcct attattctag gtagttcact taaagttcct tgtccaaaat
    94081 ttattcttga tggttgataa aagttaatca tatttttcct cccttaaatt attgacttca
    94141 tattcaaatt atacatatca taggattttt aaggcaatac cttcactgtt aactcttatt
    94201 tactaaagct tatggcaatt attagacaat aaatgtttta ttattaccat atcattatgt
    94261 aaattttatt aagtacccat gttataattt tataatcaat cttattgtat aattgactta
    94321 ataataaaaa tagagtatat acactttttt atgacaaata gcttaaagga gaattaaatt
    94381 atgaaatatt tgatagacag tgctaatctt gatgaaattc aaaagtgttt aaagtatgga
    94441 tttaagggaa taacagctaa tccatctatg tatcttaaag agaaggtaaa cttccatgaa
    94501 tttattgaga catgtactaa tttaaatcca gaaatattaa ctgctgaagt cattggaaat
    94561 aatttatacg aattaattaa ttcatgtgat aagatattaa atataaataa aaacactata
    94621 ataaaaataa atttctctga agttggctta gaacttataa acatattaaa tagtaaaggt
    94681 gtaaaaactg catgtacctt gattttcaat gtaaatcaag catcattagc tataaatgca
    94741 ggtgctgatt acctattccc ttttataggt agaaatgatg aaaatgggaa tgatggtata
    94801 aaaaacctta cagaaatatg taaccttata tcaataaatg gatataatac taaagttgtt
    94861 gcagcttcta ttaaaaatgt attccactta actcaagcat ctctttgtgg atgtgattat
    94921 gcagctgtaa catatgattt atttaaaaaa gcttctttta accagcttac agtagatggt
    94981 gccaatactt ttgaaagaga ttggtccaag gttaataaat agtaactaag atttaggagg
    95041 gtttgcattg aacaaaagat tattagatat tgctgaatta ttactcaaca gctcagacta
    95101 tattactgta gatactattg ccgaagaatt aaaagttagt aataaaacta ttcgtaatga
    95161 ccttgttatt ttagatgaat ggcttttaga gtttaattta tccctagata aaaaaactgg
    95221 ttcaggggtt attattctag gtaatgaaga tataaaactt aaagttatta gagatatcaa
    95281 tgataaatca aattgtatat atgcatactc tcctgaagat agaaaaaggt atattctaag
    95341 taaattattt attaaaaatt ctaagtttag gattcgtgat atttgcaatg aactacatgt
    95401 tagtagagct actgttcata aagacttggt agttattcaa aattttttgc aaaactttaa
    95461 agtgactcta gttagaaaaa ccaataatgg agtatattta gagggaaaag agaaagatat
    95521 tcgaaaagca gtttttgaac ttgctactgt taataaaagt tatactgaac ttaaagaaat
    95581 attattctcg aactctaatg aatgcaaaga taccccatca acaaaaatat ttaaggagct
    95641 atttaactat gattttgaga aattatctca aatcactcta cacaccttac aagtagaaaa
    95701 aagtaacctt agtgatgagt attatataaa cttcttaata catatagcta tatgtattaa
    95761 gagaatttca attaaaagat atattaactt atctgaaggt ttttttagag aattattaga
    95821 acatgaatac tttgaaaaat caaaaatttt atgtgctaac ctaagtgaag cttttgacgt
    95881 agaatttatt gatgaagagg tctgttatat acttcttcat atagaaggat tacttaaatc
    95941 aataaagaaa actactactc ttgaacctct taaaaatgaa gaaattacag agtataatct
    96001 atctgaagca atagctgttc attggggaag tatactaaat ttaaacttaa aggatgattt
    96061 aatattaata aagtctcttg ctaatcacct taaatcagtt ctacacagaa taaactatgg
    96121 atttactatt acaaatccca tattaaatga tataaagaga acatttcctt atacttataa
    96181 ggctgctaaa gagtctaata ctgttatcaa acagttgatg aattatgaag tcaatgatga
    96241 cgaaatagga tatcttgctt tatatttaat atcagcaata gatagaagca aatctcccct
    96301 aaatactatt ttaatatgtc actgtagtga tggtgtatct aatttattag tccaaaagtt
    96361 aagttttgaa tttaatcaga ttaatatagt taaatctata cctctatctt ctatttcatt
    96421 tacgaacttt gatgatgtgg acttaatact aaccactgct cctgtagact ttgaacataa
    96481 tgctgaactg ataaatataa atgctctttt aagtaagaat gatatttcca gacttagtac
    96541 aattataaaa aaactatatt ctgaaaaaaa taaaatatta tcttataaat aaacaaaaat
    96601 aggcttgtct caacatagag ataaacctat ttttcattgt ccaaatgata aaaatatatt
    96661 tgatttcata gaaaaagtgc ctcatgaact aaaaaattca ttttgagaca ccttcatttt
    96721 ttatatttaa tctttttatt taagctttta tattttttaa acttttatat tttttaaact
    96781 tttatattta aagtaaattt tattattttt attgagcgca agcattattt atattattaa
    96841 tttcttcagt attcttacca aactttgtag ttacaaatcc tattgttttt attatgagta
    96901 ataaggatat caatgaatat atagatatca taaaattctt acttattatt ccagatgcta
    96961 ctattataaa tccatctagc ataaataata taactggcaa cttcagaaac ttaattacct
    97021 tattaataag cattgcaact aaatcagttc caccagtact acagcccctt attattgcta
    97081 tccctatagc agttcctacc aataacccac ctatcactcc tgctactaat agattgtcag
    97141 ttatgtgagt ttgtggtatt acttttaaga ataatggacc cataagagtt atatataatg
    97201 tttttattcc aaaacctttc cctaaaaata ataatcccat tactaaaagt ggcatagata
    97261 ttcctaatga tatattctca acaggcattg ataagaatgt gctaagtacg actgataatc
    97321 ctgttatccc tcctggagct aatgtatgtt ctgcaaagaa aaaattaact gctaatgcca
    97381 ttaaaaatgc tgatattgtt atcagtaaat aatcttttat catttctttt ttcatttaat
    97441 aacctcctat gattatattg tttcagtata aaaaatcaat taaattagtc tagcttcctg
    97501 tagtttttca taaaattaat gcttccttaa aacattaaga aagcatctct tttatcatag
    97561 tttattatct tattctaaac caaactttgt agctgcttca tctatagctt ttctacaatt
    97621 cttaacacct gctgttatac catctttatc cttgaatatt gctgaagata atattacaac
    97681 gtctggatta cattctatta atggctccat attgtctgct cttagtccac catctattgc
    97741 taattcacac ttaggattct tttcgtctat catttttcta gctcttttta ctaaatcaac
    97801 agcactcttt ctccatcccc agttatcttt tccatcagtt tcatcaacac catgaacgac
    97861 tatttgcaat ctatctatat catatatagc ttcatcaaca aaacatagtg gtgtgtaaca
    97921 tccaattgtt aatcctactt tcataccaaa ttctctacag taatttatta tgtatgcaag
    97981 aggagcgcct aaaaaatgtt ctgctggtat tatcaacaag ttacatcctg ctgctgctat
    98041 tttttctata aataatctat cacaatctct tgtgtatata tggcattcta ttggtttatc
    98101 tgtcactggt cttattgctt ctattatttg atgaccaccc ataagttgca tattttttaa
    98161 gtcatgcata tctgctgcat ctgaatgtac gtagtctaca cctgcatcca ttgcttcttt
    98221 aactacggct gatatatgac cgtaatttac atgtgctaat cctgctgcta tttttatgtg
    98281 tttcatattt gtatacctcc atattttact ttaattagta ttaaatatta gtttttgata
    98341 ttttttaatc cagtattact tttatttagc attactttta ttgctgtata tatttctttt
    98401 atgaacttat tctgcttttg ttaactgtga acttattttg ctttgtaaat taatattaca
    98461 ctgatatatt ttttttcaca acactttgac tactccttaa aagtaccttt atattgtggt
    98521 aaattataga cattaattgt atataaaaag ttagtttttt accacattct tatggcattt
    98581 attgtctata ctaactcaat tgatatagct agttcattta atatataatc agactataaa
    98641 tataaattta ctcgataaaa agtaccattc ataacaatat taatgaaagg gagatgtaaa
    98701 atgagaaact gtattattgc ccaatctgga ggccctacag ctgttatcaa tgcttctgca
    98761 gttggtattt atgaaaaaaa tttagaaact aaatactttg ataaagtata ttttggtatc
    98821 aatgggattg aaggtatatt aaacaaaaat ataatagatt cagactcctt aaacaaagat
    98881 aatgtattaa atttaaagca aacaccttcg tctggtcttg gttcttgtag atacaaactg
    98941 gctgattata aaataaattc ttatgattat gatagagtta taaatatact agatgaatat
    99001 gaaatagata cattatttta tataggcgga aatgattcta tggacacagt gatgaaattt
    99061 tctcaatact gcaaaaacac tacttgtaaa ataaaattta tagggattcc taaaacaata
    99121 gataatgatt tattaggaac tgacaactgt cctggatttg gttctgctgc aaagcttatt
    99181 tctacactaa taatggaaac atacttagat ttttctatat acaaaaataa tggtatattt
    99241 atagtagaaa ccatgggtag agatactgga tggttagcag cttcttcttc actagctaga
    99301 cttaatgata ctccacttgt tgatttaata taccttccag aaattgattt ctatgaagat
    99361 aagtttatag aagatgttag aaaaatattt aaagaaaaaa ataaggctta tatagttgca
    99421 tcagaaggta taagggataa atacgggaac tttatatgcg aacaaaaaac ttctgctcat
    99481 gataaatttg gtcattccca attaggtgga gtaagcaact atctaaagaa tcttatagta
    99541 tcatcatcaa ttacaacaag agtaaaaacc ttagaacttg gtgtaataca aagatgtgct
    99601 atgcatttag cttcagatac tgatttaaaa caagcagctg aagttggtgc atatgggata
    99661 gaactatcta aaaaaggata tacaggagtt atggctatca ttaatagaac atgcaataat
    99721 ccttataagt atgaagttag tcatactgat atttctaaaa tagctaacaa gacaaaatat
    99781 tttcctaaag agtggataaa tgaagaatgt aattatataa ctgatgaagc cctaaattat
    99841 ctatatccac ttattcaagg taaaccagat atcaaatata aaaatggact accttatttt
    99901 tcaattattt actaggaaat tattataatt tgatatacac tcaattctat cgctcttaaa
    99961 tacctaagtg gctgttaaat aaaattataa attgttatat gacagtcact taatcgttta
   100021 attatttaac tgtttagttt tttaattttt taatcttttt taatactaat acgatttgtt
   100081 gtaataatat ctcacaccca ttttcatttt ggatagatta taattagtta gacaataaat
   100141 attttgtcat gatattatta tatatagtga tacaaataga aatactttta tcatgactag
   100201 aaaaacaaag attacacaaa ggatttaaaa atcaaacaac ttcaattaaa ataaatggtt
   100261 aaaataactt ctaaatcaac tacataaaca ataaaagaac ataaagtagt taaatctaca
   100321 attataaaat tggtaagact ataataactt aaataaaatt aaagttaaca aagactatta
   100381 aagttagcaa atattcctct acctaaataa ttgcttttta taaagagtta tttattttaa
   100441 tttattttaa ttgaaatacg attttaacta gaacaataga ttaatgtaat atttaatata
   100501 aaataattat aataattgaa aaggaagtaa tctatgatga aaatagcagt cataacaacc
   100561 gaatttttaa aagagtttgt agataattct ataaaaaagt taaatattaa tgcagaaatt
   100621 gaaatatata tctatagaga tttttctcat gttggagatt tatatttaga aatagaagat
   100681 aggtttgatg gatttgcagt tagtggcccc atccccaaaa aagctattac aaaaaaggct
   100741 ggaactatta aaaaacctct a
//
LOCUS       DAMJWO010000004        89456 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.005, whole genome shotgun sequence.
ACCESSION   DAMJWO010000004 DAMJWO010000000
VERSION     DAMJWO010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 89456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 89456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..89456
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.005"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            283..738
                     /gene="smpB"
                     /locus_tag="PC366_000304"
     CDS             283..738
                     /gene="smpB"
                     /locus_tag="PC366_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HDF2575865.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
     gene            896..1245
                     /gene="ssrA"
                     /locus_tag="PC366_000305"
     tmRNA           896..1245
                     /gene="ssrA"
                     /locus_tag="PC366_000305"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1919..2824)
                     /locus_tag="PC366_000306"
     CDS             complement(1919..2824)
                     /locus_tag="PC366_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P63C domain-containing protein"
                     /protein_id="HDF2575866.1"
                     /translation="MESKEKSILRATHFGIIKIGEKDLNCAVLENGSRIINKSTVFKA
                     FGRTKRGRKKDEIRVPSKPNLPSFIDAKNLSDYISDELEDMLINTIKYKTKNGRIVEG
                     YPAEIIPLICDVYLQARLDNKLAVQQEGLAIASEILVRSLSKIGIVALVDEATGYQYD
                     RDRDELQKILSMYISKEFLPWTKRFPDEFYRQMFRLKNWTYPRPSSKRPGIVGTYTNK
                     YVYDLLPPGVKEELQRVNPTVKPGQRKHKHHQFLTEDIGNDHLKNHLLKVITLMQASK
                     DWKDFNVLFNRAFNLPVQLEIEYDE"
     gene            3735..3950
                     /locus_tag="PC366_000307"
     CDS             3735..3950
                     /locus_tag="PC366_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3791 domain-containing protein"
                     /protein_id="HDF2575867.1"
                     /translation="MDERKLEFSIFCIEALAEKLNIDSEGVYKLLKHDTDILDNYIIP
                     CYEALHSQSKSYIVEDLIQVLEEKGVM"
     gene            3950..4429
                     /locus_tag="PC366_000308"
     CDS             3950..4429
                     /locus_tag="PC366_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3990 domain-containing protein"
                     /protein_id="HDF2575868.1"
                     /translation="MIVYHDSYCVAKTPNIIFLRDSLDFGKGFYVTSIKTQAINWIER
                     FKKRGKKAYLNSYSLDIDKLKENCKVKIFNSYNLEWLDFILECRNMSDVYMKYDVIIG
                     GIADDKIYNTIELYQDNLIEKDEALKRLKYYKPNEQICITNQNVIDKYLKFRCEEEV"
     gene            4435..4665
                     /locus_tag="PC366_000309"
     CDS             4435..4665
                     /locus_tag="PC366_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575869.1"
                     /translation="MEANKTLLQILYKKIILEFSNQTGKSLEESMDYLYTSETYKLIS
                     EGVSDMHCKGHIYLAQELMLENGLMYHKGYPR"
     gene            complement(4781..5947)
                     /locus_tag="PC366_000310"
     CDS             complement(4781..5947)
                     /locus_tag="PC366_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF2575870.1"
                     /translation="MATKRANGEGSIGKYKDGWRSRIMIGYNEDGKPIRKEFYGKTQK
                     EVKDKLDAYKKQYYLSSDISDDKITLEHWFYNWLFEYRIKDLKPKSFERYESIYRNYI
                     KDTDLGNVKLKDLRVSHMQKYYNRLLDSNKSIPTIRQINTKLKTCLSEAEKQGLIQRN
                     YCTMVNIPVEKKENRLEILTLEQQKNFIKAIEGHKLEVLFLVALGTGLRLGELLGLKW
                     FDIDFKNSNLTVKRTLQRTYFIDKNGNRELKVLEQEPKTSNSYRTVPIPKDVLNKLKE
                     HKVNQNVDILKAGELYRNDNYVFCNELGVPIDDKRPLRNLKSILSSLDIEPIKFHGLR
                     KTYATRLFENDVPPKTVQVLMGHYDISITLNIYTQVMEDKKVEAVEKLDKIFSL"
     gene            complement(5937..6689)
                     /locus_tag="PC366_000311"
     CDS             complement(5937..6689)
                     /locus_tag="PC366_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF2575871.1"
                     /translation="MNKSYIPKYTHKFPTNLPHGDKKYTLTYIRRMISEFVYDMGNLE
                     NNPFTFPEVQTLLDGITVGGHKLSDQNQILNIKSSWDYIIKLSNKENLSLNKDTICSI
                     HKIVAKDEALIVGDFRNGNIGIAGTTQYECIEATLLNNLFISDISIINKITNPLEKAI
                     IINLWLSYCQFFYDGNKRTARLTSNLILISNDIGVLSIPAKHKQEYNTLMLNFYETLE
                     ADEVIKFLLEKCITFFDGYNYKSYKELFKNGN"
     gene            complement(6781..7272)
                     /locus_tag="PC366_000312"
     CDS             complement(6781..7272)
                     /locus_tag="PC366_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2575872.1"
                     /translation="MINNTIGEKIKQYRKSINMSRNELANKIGCSVHAIAKYEQNQRI
                     PSLDMIRKISTALSIAINKLIVEENDLDTLTNNNINLKVFDKELDLVVHILENYGYDI
                     KTDYKKKFEITDNADTIKPISLSFSDFKDFSKNLNWVINGLVENFIQENSNGLIEDED
                     EEY"
     gene            complement(7269..7466)
                     /locus_tag="PC366_000313"
     CDS             complement(7269..7466)
                     /locus_tag="PC366_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575873.1"
                     /translation="MNKAYMLKYTYKYPTNLFYGDKKYTLTYIKRIMSKLVYDIDNLE
                     NNSFICVKIQSLFDDIFKVEL"
     gene            complement(7523..8287)
                     /locus_tag="PC366_000314"
     CDS             complement(7523..8287)
                     /locus_tag="PC366_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2575874.1"
                     /translation="MQIGKNLKKIRKQKELTQIQLAEISGISRNALINYENDKRIPSI
                     DTLSKLAKALKIEKTIFYFDIENEVMTNEDVLYFLQSLFPEEYYSFDEFLNAISNLME
                     DDDIRITSSLLLGAWSDKDQYYKLGEKLELNENQVYNWILSDCVSNTELDFSLHPDDI
                     KEIIKNDVLIKQSIDELLDIGLSEENIEAIYDYFSEATDNGSNIRLKKLISQKENMTI
                     KNNDYFKLLQENNELKEKNKKLENTLKEIKKLLTKI"
     gene            8434..8634
                     /locus_tag="PC366_000315"
     CDS             8434..8634
                     /locus_tag="PC366_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2575875.1"
                     /translation="MGINLKIFRIKKGLKQQELADRVGISRYYLSNLETGKANNPSND
                     LMIKLSRALDTTVEELFFSKEE"
     gene            8638..8952
                     /locus_tag="PC366_000316"
     CDS             8638..8952
                     /locus_tag="PC366_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575876.1"
                     /translation="MKENNNLEVLKTLQATLNIIVKNEEEAQEKKQGYKIIENAKRNK
                     AELITCKEASKLYPIGESKFRQLCHSKNKGFPCIWINNRVYIIKNKLDDWFIENANGI
                     KL"
     gene            8974..9717
                     /locus_tag="PC366_000317"
     CDS             8974..9717
                     /locus_tag="PC366_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575877.1"
                     /translation="MSNKGWIKLYRELLDKSIWKDIKPERKVILITLLLMASHKENHV
                     FIDNKRIKIKSGQFISSYSKIAERCGKGVSYQMVRSCLLVFKNAGFLTYETTNKYIVI
                     TIENWELYQENIENQQPNQQTINNQSTTIKNIKNENNIIYSEIISKFNSTCIELSKVK
                     KLTDTRKRRINSIIREYDKEAVLEVINIVSKTSFLNGNNNTGWKANFDWIMNSSNFTK
                     ILEGNYHSKEIVINKETGIYNPDDSQLKW"
     gene            9730..11064
                     /locus_tag="PC366_000318"
     CDS             9730..11064
                     /locus_tag="PC366_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2575878.1"
                     /translation="MNNSNNLIKNTEAEQSILGSILLDSTIVEELEQMLNEDMFYHEE
                     HKYIFNAIKEINKRNEVIDIITLTEELKRKGHLNNIGGISYITSLSTIVPTVSNFTSY
                     VSIVIEKYKNRNIIDKFNKFNLGEIDDNTLIYQLENDINKANQKLIKKDSSITAISER
                     AFEYINDEMNEGIKTGIKFLDDTIGGLYGGELTTIAAKSGRGKTALALQILRNVIFQG
                     KKVLFISGEMSDIQILFRNIASLTGISVVKMKNRNLNDDEIVKYIQALSIINQENNLY
                     INDSVNTVSGIKREIKSTKPSLVIIDYLQILDYEGKEVGEAKFADLSRQIKKITLDFN
                     IPVIQLAQLNDELKDERPKGDRVMRSSKQIYMDSNSVIYIHRPTEKEALNYCKTMGIE
                     DIRELRRREKGFGANLSEIIVAKNRDGESGFRPYWYIGNLFSFEECKKIQEI"
     gene            11314..11586
                     /locus_tag="PC366_000319"
     CDS             11314..11586
                     /locus_tag="PC366_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575879.1"
                     /translation="MYDEIIEIYFDYWINEHMYRSILEKDEYYIECWKEVKKINELLE
                     INLEDDKKYLLVELNDLFNSLIEFERELSYKLGFKTGAKFIIELLK"
     gene            11859..12986
                     /locus_tag="PC366_000320"
     CDS             11859..12986
                     /locus_tag="PC366_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDF2575880.1"
                     /translation="MIIPKLEPNDRKREFNKYSSEQINKVVYNYLFKNNMSNRKIDDE
                     ILDLSSKQSKGYQSMGIVHHLGINKNHKGIFTGYTIDKAIEVLKEDEIHFKQIINILL
                     EIRNINEYPIIVDSWELLDEKIALKTIDKSTLKHNGTGVPIEIRYFFEINNLGKNEKK
                     NVNFKYNDNYYSAVIEMDKLENPRSRIIWKSKFRDLLRSIFSEYYEKFLENKIEGKTN
                     LPKIRFIKLDSNNFNIEFIFTAEIEDDVLEEISQDNPLNINTINIELETEIRKEGKVK
                     YVYGKQYERNPRNRIEAIKYHGTKCIVCGFDFEKTYGDRGKGYIEIHHIKPLSSVGEE
                     SNINPKTDLVPICSNCHRMIHRKKDNVLSIDDLKQIIKDSK"
     gene            13466..14113
                     /gene="cas5"
                     /locus_tag="PC366_000321"
     CDS             13466..14113
                     /gene="cas5"
                     /locus_tag="PC366_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HDF2575881.1"
                     /translation="MILNKIEIIGDMAHFKIPMHSKIQRTYEIPPISTVVGILKNIYG
                     EEIDDFILGYVIYHDGTFKDLQTIYKEINPNVKTLTDSDRFQTDVCPIEYLINPKLII
                     YTNIDKNIEFNEPLCLGKTNCLAKVLSLSEIEVNLIDKKAIGYNQYTDINIGDGMIKR
                     INTLTEYNEKKGYYDIYSSMVRENDEFEYGKYYDEDEQQNIFLWKWKKGGVIKCI"
     gene            14104..14868
                     /gene="cas6"
                     /locus_tag="PC366_000322"
     CDS             14104..14868
                     /gene="cas6"
                     /locus_tag="PC366_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HDF2575882.1"
                     /translation="MHLVRRHLILTVDNEVVLDYNYQYELMKRIYEAIEINDKRKALS
                     LHNEGYKVDKKVFKLFNYTIMFENAKYLKEGIHLNPQTKIKLILSGYDDILNNIIKGF
                     IKCKVFKLNNIEFKVSDIEEDSKKNFNNITLYKVRSPIVASLYDLKSRKQVYLNPMQE
                     EFYKALHDNLGNKYKLIHNKEYTGELYFDIEDVLAVKKKYITNIKGKGFIIGYTDFEI
                     FVQANKDMQEVIYYCGLGEKNSIGMGLLTYITSRRA"
     gene            14870..16036
                     /locus_tag="PC366_000323"
     CDS             14870..16036
                     /locus_tag="PC366_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575883.1"
                     /translation="MDRSYNVFVDNGLYVLAYYLNKDINDITYQDIENSIDLMSDKIE
                     EFVSCEKYSNLKSMCFSNSTLTQPKGKVTLNEKLKGFVKNQGDEYCSLCGQYKAKVKI
                     EDKEYNIGRSYMPNLVANTFYNFSNNLQGLNVCPYCLVLTMYSILNCRVSRYAFLYNS
                     TSSEFMEDYTFHIQKENLTDVELGAKKEKEKYSIVKLLESLVCKYNLFNGDIEQYMFN
                     NSGQSQDIQVNRIKNKYVNLLIKLQEKALLSNFEKLHLDRYILNGTLESNYLREVYRV
                     KKEEKMDEKEQKNFDELVIFLNREVNVLKKVKIDIIKKLTDKLKTSDLDIDKIYKELK
                     MLGKFYAYEDWLVNLNEMYYEKTGEKLFEAEDYIELDDIRSFRQIKNLILVSLI"
     gene            16057..17127
                     /locus_tag="PC366_000324"
     CDS             16057..17127
                     /locus_tag="PC366_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
                     /protein_id="HDF2575884.1"
                     /translation="MENKNSNRMLNIGYAIEVLCGRLNGSSSEVEKKNNSYKNSTYTK
                     KIGSRSRISSQCQKYNQKLFMEQVCGYEQNVKTKDGKQVKLVPNPFKYATDDIFGFMM
                     AEKLSIEEDVYKELSDEEKEIYKKNKKKYEVNITKKRKSRWQMNSLINVSNRKVEWEW
                     NVCGTTGDSMPYQVEVYSGVHTNIANLNIGKIGEYDISDIASEHRDYTTLEAKSIGVE
                     KLDKEEKFKRIEALLKSLEYLSVEGNKTNHLTDTKPKFVILGEYSWGNNVFQGIIKEN
                     GLDVEMLKESIEQNEEFRKSDIWIGINKFYDDTFNEIEVNNEKEQIKKYLEEEFEEYD
                     FMKISNVHQAFESYLKYLKETL"
     gene            17138..19123
                     /locus_tag="PC366_000325"
     CDS             17138..19123
                     /locus_tag="PC366_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HDF2575885.1"
                     /translation="MNNLYEYKAKSDGTSIDKHNEDMNYIMNQLVSIYNISNDMKNDL
                     YEAIVCHDVGKVVKSFQDNIESSTRRVRHELLSASIKYLNRGQKLAILTHHKDIKFLE
                     GQITNSIYEIELKELKELLDIEVEDIRPFIKEISRARNDDTRKLENILLKGYLQYCDH
                     IASAGIKSIDKGFNSIKDFSIPKGVSYNSIQEKVLNMDKNEDIMIMAMTGLGKTATSL
                     YWSNLVQNEYKSKRVYYILPYTASINSLYENLYNRNISVSMLHSKAPYFLNKISDEED
                     IKQLYQIYKKSVKQINVCTIFQLVKSVFSCKRFEMLLSQLKDSIFIVDEIHCFDTRVL
                     CYTLEFLKYLKENLNVKICIMSASIPTCLKKLIQERLQISTIIEPDSKDLIFRHRLNR
                     LSEGILDSIHKIENDLMQGKRVLICVNSVDLSQELYGRLQKYNPKLIHGRFNTRDREQ
                     AEKGIEESFLLIGTQSIEVSLDISYDVLYTELAPLDSLLQRFGRVNRRGDNAELSNIY
                     IYDYDRKLNIYDEDIINRTDIVISDIIHNDNSIVDESKVPSYLDNVYLDIDMDKYNKH
                     KVALEIIMKNMRLGVWNKSANNDMLNNDTISVVPECLLEEYKLYIDKKMYLEASSLFV
                     NVSVKRYNYNKKMFYECGDIVVTSYSYNDKLGLIFDC"
     repeat_region   19376..19998
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=19376..19404
                     /rpt_unit_seq="gtttaaattacactaagttagttataaat"
     gene            20443..21999
                     /locus_tag="PC366_000326"
                     /pseudo
     CDS             20443..21999
                     /locus_tag="PC366_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003444896.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            23177..24391
                     /locus_tag="PC366_000327"
     CDS             23177..24391
                     /locus_tag="PC366_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FRG domain-containing protein"
                     /protein_id="HDF2575886.1"
                     /translation="MGEKMQSVICKIFDNKLLISNDLSEQDDVLYEVMDKFIDDIEYI
                     SKLGDEQIKSMLMEVNKFEEDSTEFELYMKNLCYLKQSYFIDTNDKSEINSIDIDILK
                     NVKIEDLVDITNIKLERNLNINIEHISKAVNKIYEENEKWKEYNIQNTMSKYIGIPES
                     EVIFISNLSQYVSFLSELDNAGDYVSRGQKDCMYELLPSLHRKYKKDYGIHSDEYEEA
                     FKQKIIYYDKEIKNRSSEELRAEGQHFGLPTEYLDFTEAHLISLLFAIEDYKYTKQHS
                     IVYFIDSISYNTDTIKRSEKLVNYSDTSAIDNCSKFSSRSFFIKVGNSNERIHFQKGC
                     FLKVSSEDKGEFKEKLKKYCKVVVINKDAKKEILKELFNLGITFENIYPDKDNVVKSI
                     KFYYDEIVGGNL"
     gene            24391..25683
                     /locus_tag="PC366_000328"
     CDS             24391..25683
                     /locus_tag="PC366_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HDF2575887.1"
                     /translation="MREQFKNSIKNIKSNRPLVSVQDIVNFIDKGEKYLKLSIDEIDE
                     MEILQGIVMSPDYQRTYKSSNKEESSIIESLLIGIPIPEIFLVKIGVNDMQIRHVMDG
                     QHRLNAIYRYVKNKYPLKNLDILGNDPLYDNKRFSELEKKDKIKILGSHLSILEFDGF
                     DNPEIEIELFKRYNRNTKPLEMQEIEMATYFSETSKYISKFINTLIKDKYKDEIDKSE
                     YKYANYKSDLLRIYNITKSRNDKQKNHQEICIIFSILENGLQENIRDGVTASKKFLEY
                     KSIQYKNNESEKLELLKDKFDEFNRMILKISEKIEYPFSTSLISDDKQRQSKYLIGVS
                     IVLASICYYYDIDLENNYLIQDIKKIISCSPIADIEYKASSTNMKNMILYLFIKNKIQ
                     DNKFESLNLKRDKIKEINTLVMNNDGYLNEQTRLLEIY"
     gene            complement(25910..26095)
                     /locus_tag="PC366_000329"
     CDS             complement(25910..26095)
                     /locus_tag="PC366_000329"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDF2575888.1"
                     /translation="MEGFWRILKVEMYYLRKLDTYEQLVKTIEDYIYYYNNFRYQKRL
                     NSMSPLEFRKYLNTEIA"
     gene            complement(26125..26514)
                     /locus_tag="PC366_000330"
     CDS             complement(26125..26514)
                     /locus_tag="PC366_000330"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HDF2575889.1"
                     /translation="MRAVGLSSVCRKKKFSYVKCTPEVIAENVLSRKFSADKTSQKWL
                     TGVTEFKLTNGMKAYLSAILDLDDRSIVSYVIGKSNNNNLVLETFDKAIELYPNAKPI
                     FHNDKSFQYTSKVFKSKLLTQGMIQSM"
     gene            complement(26526..26986)
                     /locus_tag="PC366_000331"
                     /pseudo
     CDS             complement(26526..26986)
                     /locus_tag="PC366_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888992.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            27415..28425
                     /locus_tag="PC366_000332"
     CDS             27415..28425
                     /locus_tag="PC366_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575890.1"
                     /translation="MITKIKKTYIYLKEIQKIYKINEHKELVHIIKKLINDNKIKPIK
                     TSDLTPQHEQLYTKYRIIKQETEEDKKILEEINYKICDKLSIDYYRKNLVHYKNNRVA
                     IMDLNSYLIKKSDNLSKKISINERSYEIFKDEKFISSKVGKEVLKNLKIDLIKDLNVY
                     KTPEPFIYLSINRISPQKILIIENKDTYITITKMLLEGKEILKNKIDTVIYGEGKKII
                     NSIKGLKEDITIEYLTNKENEFLYWGDIDKTGLSIYTSLKDTNEINNIRLFEVAYEHM
                     IDKTKENTLRNIPKNQKDNFECGLENINNLNLKESIKNILVQGKYIPQEALNRFDLEE
                     YN"
     gene            28425..30044
                     /locus_tag="PC366_000333"
     CDS             28425..30044
                     /locus_tag="PC366_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575891.1"
                     /translation="MEMINILEGYNKRVNCIGSYYLIATLANNRNKFKEFDNIQFYNL
                     LIQVLCYIFDRSLRRKNCLRDDIKDFIEEINRMDYKIMLSEDDLKDLANYIINGLTNS
                     GKVYLFTYYSLEQEKHIDESIKIIEDKNVKINNQERLSYSLTTEGYRLLLSTKEYDEL
                     FQIQISQMIAKLRIEKGDYQGAKEDIYDIINTLEIHQQKIDNYIKIIKVNILYIKEEK
                     YSTVIDTTVETLLEEMDKYEELKKEVKLLIKDKEDYLEKDEDIDKEKIKNIRTQLLQM
                     KELIDGIVLAKSTATNLLSRVQDFREEFKEILKKLLTTPVIKRFNFKEEILDRLEKDS
                     DFLLIIRELYISLFKVELPNRFNIGVAYQEQKLLNTREIENEIVNKDELEIIENKEKE
                     ERINYCENYYFDFFKYLIKYGLEKGQFTLEEFLKNYLKYDKVIYLEITKDSKLMRDII
                     IYFANQRESINIKKIIRMLENSAFSPNTDFQIERLIERLLVEDFELLNSVSHIKSNKI
                     FEDEMKINTEINLETMTAVKLEIANIKFEII"
     gene            30062..30790
                     /locus_tag="PC366_000334"
     CDS             30062..30790
                     /locus_tag="PC366_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575892.1"
                     /translation="MNISLNDYKIANEIFYRLLKKSELKEKEAKELFLAYINNSNVRY
                     ALEAICEVSKIKIILISDTLYLIPNNDNDIFGFDYRRESLLGKDLKDSYLGYLIMTII
                     FSEFTNGVAPASYIQVLNLLDLVQESLERSIARDNLEEIEKSCEFNITILKNYWESKR
                     KWDESSKKGIETTSADFQIGFIRKIINFLKNEGLIVHIEDEDKIKPTRRFLDLMNNYF
                     LDEERKVLIEKLVLRKGESINASN"
     gene            30777..35132
                     /locus_tag="PC366_000335"
     CDS             30777..35132
                     /locus_tag="PC366_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575893.1"
                     /translation="MPVINKYKIINFKFGMGQERILSNRTMELYGENLQVEAENTAGK
                     TMSIQTIIQSICPLSDVAKPFTAIYNKKEPLYSMTEWLLDDGKTLLLTGIGFEKKAGS
                     SKEEGKEKKDDLYKYFMFIIEESKEMEVDIDNIPLLKNNDKGIRIVQPLTASQDYIKM
                     LRDKYGKNKVHFFNNYLRKQHREKLEEYGINQSEWKEIIIKLNSNNKEGGLSDFVKEH
                     NTSEKLIRDKILPLIETSLTTEEFAPILQIKEQVRKCINNIIDMNEKLSDYKNYRDLN
                     IRVESLQNKINRILFIEEDKNNVLGELANLYVHIENKRNELNEEIKQYQKMKASKEEE
                     FKIVEYEEDSYEYFRKEKEIQDTQVEFDKAKNELNDKIEELELDEQYLNISKFKRKKK
                     GLEEGEKDKIEKESEKQRKEVNQEEITAIINRLGSSIHYCLKEESIINNEKLKENTNN
                     NIAIQEKKNQLNDDKSKLTKVLISKNSEIKYIEGKERDFNNQLHEFKLNNTDIKGFIS
                     NNFLGEVIDYTRYINYLNIKVKSIEENLESKVMQIEESNKLKDDINEAINNLKLDNHE
                     SYMKLQVLKTRKKDIDNFKEKYKIIKTRFEIDNELDNSTKLYKEVKQELNKMKLQVQD
                     LENNKKQLEKELEDLQNYKDIIFEEEILTDLERNGIKPIEGMKYLLTLDGDLEYKNNL
                     ISKNPLLPYSIIITNKEYQKLKQINLKNKTKISMPIFVRDNIEDTFITTSSNLVISNG
                     LNILSSFDNKALDPEKREKDMNLIKEQINSIRDKVEQYKAEIEILEEFKLLTNKIDFT
                     AEDLSIDVKIENYKKIIFEINNKIKSNENNEKNLSNKIKELYENKEKLLNNKNILFNK
                     LKDIRNIQDTYSIILENKNEITKLKTSIEKIEEEKKVIKKSIEDIDVNIFNLNSEKDR
                     INRHIDDTESKINKFKIYEPIKLENAKLEELEIKYKKYLEDPTKKEIETLNYEISVCL
                     KRIESITIELEEFRQLISSDNFENIPILFTIEELNKRIVLNKSKVDELRKLKYSIKSD
                     IDKNQGSLNTKREEILKKFNGKEPLSTSLIVNFNFEERKIDIKKDIKDIGEIIEGNRT
                     TCQNLEQELRDLKKYKVERKAITYQPEDIFIESKKLQSKLQNVEYNLIKSINSYKNTI
                     LEIKEFNYKHMEKYKNFIETLNVNKDNYSRQKEQVEIVLLVIREEISKLEKHSEQLRK
                     EKTIISRQIKDYVMDCIDEFKIINKLGKHKGQALFNISLPKSDKIENSLSLVDMLMDE
                     IVEEANLGDVEQKINTFYILNKTLNIGRIPVSVIKYEINRNETIKWNSINNETTGGQR
                     FCISFIVTILLMEYKRYDRNAIVDESKYKGKVLLMDNPFGETSQQDFLKEIFELAKKF
                     NVQIISYTHVTNASIRAMFNKIYLMTVEKTTSNKEFVDINEIKQNKTDELVYMSKFYI
                     GNKEELIQEDIFSLI"
     gene            35234..35443
                     /locus_tag="PC366_000336"
     CDS             35234..35443
                     /locus_tag="PC366_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575894.1"
                     /translation="MKNFVIVSTKAALLRVIIVRLLLKIGLKTYKYLSYFMKKEKLKR
                     IIRPEGCELRVNRSIQVERAIAEQI"
     gene            35839..35979
                     /locus_tag="PC366_000337"
     CDS             35839..35979
                     /locus_tag="PC366_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2575895.1"
                     /translation="MKIKIKKYREKLLMIQNELAKSVGVRRETIVHLENGLMYHKGIQ
                     DK"
     gene            36117..37079
                     /locus_tag="PC366_000338"
     CDS             36117..37079
                     /locus_tag="PC366_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017561613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HDF2575896.1"
                     /translation="MAKIDNMMSILWMLNSDKKVTAKQISEKLEINIRTVYRHIDALS
                     ASGVPIISDTGHNGGYTLLNNFIKAPLFFDTEEQTALLHAAIFAKEEGSFLDDTLDKA
                     TSKLKMYSNQKQEETLTKHLIGFEVIKPTGKISIESVLKKLKNSIANELSVEINYRTA
                     HEEKSKCRIINPYGIVRWNNNWYIVAFCQMRNEIRSFRVDRISSVIETSNTFNRPKEF
                     SASEFFIRGIMDETKDEDNLISLVIEGKMNALDNLCQHWLLGYYLKERTSNKAIFKLQ
                     EEIIFTYVPNILIPYRKSIQIIEPLSLRDKMVEDLLELINHYQI"
     gene            37157..37786
                     /locus_tag="PC366_000339"
     CDS             37157..37786
                     /locus_tag="PC366_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HDF2575897.1"
                     /translation="MKKRKVYMYVFDTMSDWEVGYLTAELNTGRYFKKGLKPLKVITV
                     GVDKNPIITMGGLKVLPEITIDELNIESNDLLILPGGNTWTSIGHEKILEKSKEALEQ
                     RSIVAAICGATLGLAKTGLLDFRNHTSNDLEFLKMVILSYSGEKYYKMESAVNDENLI
                     TASGIAPLEFTVQVLKVLDVFKEEALSSWLNLYKTHDSKYFFELMNCNK"
     gene            38617..39033
                     /locus_tag="PC366_000340"
     CDS             38617..39033
                     /locus_tag="PC366_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575898.1"
                     /translation="MSKSETGVKSKLILELLVITYLFIAVLATKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSKFILSKVNQIAITIMMYSIVIIAIFFATPYISNI
                     NISNLDTGIILIAVLFIQSLSKLILYIYFDKRGICN"
     gene            39034..39246
                     /locus_tag="PC366_000341"
     CDS             39034..39246
                     /locus_tag="PC366_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2575899.1"
                     /translation="MAISMKTKIKEYREKLLMTQNELAKSVGVRRETIVHLENGKYNP
                     SLKLAMDIAKVFGTTVENLFEFIEED"
     gene            39881..40924
                     /locus_tag="PC366_000342"
     CDS             39881..40924
                     /locus_tag="PC366_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDF2575900.1"
                     /translation="MKRKIAVVLLTVAMLLSLVACSNDNTSKSDKLEDTLVVYTTHGE
                     DMLGAISEEFTKETGVNVEFINLKGELADRVRSEKDNPQADIMFGGDTSTYMQLKEEG
                     LYEKTEPSWNNELDKSYKDSDGYWYGTIKTPVMMFYNTKLLSADKAPKDWSDLTKEEY
                     KDLIVTRDSLSSSMRSTISNLINYYSNTKSEEEAWKYLEDLNKNIKNYYNSGSVMYSA
                     IGKGEATISVAVLSDIIENKEKNNMPLEVVDAESGSVVITDCVAALKNAPHPNAAAKF
                     VDFVGSAKVQAMVANDFNRIPTLDSALKDSPKWMSKEYKAMDVDWSVIGKNQSNWIEK
                     WETDIIDNNKTIK"
     gene            41185..42059
                     /locus_tag="PC366_000343"
                     /pseudo
     CDS             41185..42059
                     /locus_tag="PC366_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421888.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            42078..43070
                     /locus_tag="PC366_000344"
     CDS             42078..43070
                     /locus_tag="PC366_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2575901.1"
                     /translation="MKNIELKEINHYYGKEKVLHDINISIKEGEFFTLLGPSGCGKTT
                     ILRIIGGFIKPSSGSIYVGDKNITNLEPENRNMGTVFQNYALFPNMTVEENVSYGLKI
                     KKLSKKIIKEKCDNYLELSGMKDFRKKKIDELSGGQQQRVAVARSLATEPTMLLLDEP
                     MSNLDIALRIKMREEIREIQQKTGITTLFITHDQQEALAISDRIAVMDKGKVLQIGVP
                     IEVYKSPLNDFVANFVGTSNCIGKEDYVNFNIEKETKPYIYKRPEEMILLQNTNQSGF
                     VKVKVESKNFLGAILEYTVSNDGKKYQVTELNRLNNSNKLNVGDMAYLGVLQGD"
     gene            43072..44766
                     /locus_tag="PC366_000345"
     CDS             43072..44766
                     /locus_tag="PC366_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF2575902.1"
                     /translation="MIKKINRSKFTSKNVIFIVLYSILFWILIGYIIIPIGNTFVQAF
                     QGKGGYSFEVFKEYFSNTNNLRVVSNTIILGLGSVFVCGIMGISLALYMTFVCDKHKK
                     IIHILLLSPMMIPGVIMVIACIQIYGESGIVTKSIEILLPFIKKPYDFSGLKGILFVV
                     AYTQYVYFYLNVYVALKYVDYSTVEAAKGMGASKLRVFFDVIWPVITPAVITSTIITF
                     ASGISSFSAPNLIGGGFKVLSTQIVRSKANNHMDIASVQVITLLLMGILFMILLQYYG
                     KKYGVVPSLKSQSYKVHNRKKDLFTFVCKVIIEIQIIMIMLPIVTIVYLSFVSTHSIM
                     TTIFPRDFTLENYQMIFQKSRVLQPILNSFKMSLMAVAVGLIITVPVSYLVIKKDTAY
                     NRLAKFIIMLPWSMPASAIAVNLINTFNQKSIFAFNESLIGGFYIVPIAYTIYALPLL
                     FSSNEVAMKSINLGLEESSRSLGAGRIKTFYNVIVPNMMPGIISGAILVFIRTIGEYT
                     MSALLYGVYNRPISISIVTNMQEFKIGVSMAYGVLVIGICYIALGIIFKLDRKRFT"
     gene            45317..46195
                     /locus_tag="PC366_000346"
     CDS             45317..46195
                     /locus_tag="PC366_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HDF2575903.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQGANEKNAPV
                     ILAIHPNELSFLGDSFVVSCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREIVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FVEKTGVDTLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCRELLEQNPSLYEPDTIYPPCIKAAREVIEFKMN
                     LFNAIDKLKCFYKNKN"
     gene            46231..48126
                     /locus_tag="PC366_000347"
     CDS             46231..48126
                     /locus_tag="PC366_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2575904.1"
                     /translation="MIGKILRSDCIVLDKQLQTKKDVINYMANHLYHGNYINNKEKFI
                     ADINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDREITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMEENFLKHLLSAETPYEILSIFNNKAAESGDFSNNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQLSRFIGKKVLQKKVVDAKNVSLAKNLIINAENGMAKEIKPGGKTLEDSK
                     EMLQGSETKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFPPAMIAGFMAVIGGSGFIGGMVAGFATG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSAPVAYIACILIGTVITALIIGVAKPTIRSENS
                     EVELLGA"
     gene            48394..50301
                     /locus_tag="PC366_000348"
     CDS             48394..50301
                     /locus_tag="PC366_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2575905.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKMIE
                     KYLETFNIKIDIKRGYGILIEDLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISELTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTINQPYYINLITHILICLKRIEEGNQIESQEEREISVDNLDELVYKNVTTLIDKIEN
                     RYRVKITKDEIMYIYIFLVSSGFSSENNSSYNDESDILSESEKVSSIMIENMSQFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSKRNLDDVDFVISTVNLDLKDKLHIVVSVLLMESDINNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDVAQMESLIGVNLGSKYESISLGKDLNIYIHKQSKLN
                     KGIMNINNVTRTIDIYLEISNQSFLKNILMEISNLYRQKNYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            50291..50740
                     /locus_tag="PC366_000349"
     CDS             50291..50740
                     /locus_tag="PC366_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2575906.1"
                     /translation="MEIREILTEESIILDLKSTTKEGIIQELVDKLYDTGSITLKSKF
                     IKALKHREKIGSTSIGYQMAMPHGKTKYVKKASIVIGKSKKGVDWPSIDGLPVKVIIM
                     FAMPQSGGNEDMILISKIAYILGGKNISERLLNVHTKKEILDIFYEV"
     gene            50840..51727
                     /locus_tag="PC366_000350"
     CDS             50840..51727
                     /locus_tag="PC366_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2575907.1"
                     /translation="MAIYLEMPKLIHEFPFRSLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFINDKPMQLKKGEIVIIKGGDIHYILPSPGSERLVFQFDISFFNDLILLNEEKES
                     LINLFSSIKKCSRDWSAKIRKSVFDILIDIYNEDLYKIEGYSYAIKGKMYNLIPILYR
                     QIPREIEENTVEYEINSKEILERLNNIFKYVEKNYKQPIKLEDVSYEVGFSVYYFTKF
                     FKKNTGKTFITFLNEYRLEKAKWILLNNNISIVDLVEEVGFGSTKTFYRVFKEKIGVS
                     PLEFKKRYNSLEKKGGASK"
     gene            52132..53580
                     /locus_tag="PC366_000351"
     CDS             52132..53580
                     /locus_tag="PC366_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDF2575908.1"
                     /translation="MKLGKDFLWGGAISANQSEGFYLDGGKGLSQFDKLPLNDKRLKD
                     VCLDEDNILNENNQYYPSHIGIKFCENYKEDIAMLAEIGFKCFRFSISWSRIFPTGEE
                     SEPNEKGLQLYDNIIKELKKYNIEPLITISHFDIPYSLVEKYSGWADRRVVNLYVKYA
                     EILMKRYKDDVKYWIPFNEMNMIIHIPYIGAGLTFIADENQLQKKYQAAHHQLLANAK
                     TIEIGRYINKEFKFGCMLAAGKTYPYTCKPEDVFATLEHERHNLFFSDVQVRGVYPSF
                     MNYYLKSNQIKLIIKEEDLSTLKDNTVDFVSFSYYSSACSSARAEGLEKSKANGPETI
                     KNPYLPKSNSVWQNDPVGLRITMNQLYERYQLPLFIVENGLGTQDIVNEDGKIIDDYR
                     IDYMKEHIKNMILGVNEDGIELIGYLMWGCIDVTSVSEGKMTKRYGIIHVDSDDYGRG
                     SFKRTKKQSAFWYKKVIETDGEILFNDMETHA"
     gene            53606..55996
                     /locus_tag="PC366_000352"
     CDS             53606..55996
                     /locus_tag="PC366_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDF2575909.1"
                     /translation="MSLIFTTKDQLIEQGFSKDTIKSNETLFTLANGHLGVRGNIEES
                     DFNNEYVDNMGTYVNGFYEESPITYGESAYGYAKQNQTICKLPNAHIVNFSIEGDCFD
                     LSKGITSEHTRILDLNEGIVKRSFIWENSRGRKVKVSIERLVSQDIEELMMISYTITP
                     LNFNGKIKFKNKMENSMEKFNCEKVDDPRVASINKKQFKINVKKYNNKYFMNLVTERS
                     RLGLWCGFDSYITCGNITNETYNVSDECIEREIEVYAKKDERLNLEIVVGYSRVYSDL
                     NLNEERLKSLECLESLKCLESEAHLKSLELVLREACNIGFDKVKNIQRKKMNEFWTTS
                     DVEIEGDKTLQLGIKTNLFHIYQSAGRDGKTNISAKGLTGDGYEGHYFWDTEMYILPF
                     FIYTQPSIARALLDYRYSILDASRERARELGINKGCLYSWRTINGNECSAYYPAGTAQ
                     FHINADIAYGIRTYFEATNDEEFMMQNGLEILIETARFWVEFGDYIELKNNKFCINGV
                     TGPDEYTAIVNNNYYTNLMAKYNLIYAVQMVDKFKHNLFSNEVFRKVKLQEYEVKDWI
                     NAAQNIYLPYDEEKKISKQDDSFLEKSVWDFKNTPKEKYPLLLNYHPLTIYRYQVNKQ
                     ADTVLSALLFPDEFSLEQKKRDFEYYEKITTHDSSLSRSIFGMMASEIGNHEKAYNYF
                     MDTALMDINNLQKNTSDGIHAANMGGTWMSLVYGFAGMKIKKDKLSFEPRIPKHWKNI
                     KFNILFRDNLVSVNIEEYKSYYKLIKGKNISILHDNKEIKLSKNIIEVNNCFKGSN"
     gene            55998..56669
                     /gene="pgmB"
                     /locus_tag="PC366_000353"
     CDS             55998..56669
                     /gene="pgmB"
                     /locus_tag="PC366_000353"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDF2575910.1"
                     /translation="MKAVLFDLDGVITDTAKYHFEAWHEIAKSLDIEIDETFNEKLKG
                     ISREESLDKILLSANKVDSYTKEEKLKVCEEKNNIYIKLINSLTYKDILPGINELIKE
                     LKKNNVKLGIASASKNAPRILESLGIKDEFDCIVNPSLLERGKPYPDIFIEGSKMLNL
                     KQYDCVGIEDSYSGIKAINAANMTSIGVGKKEVLGKCDHIVEDTSLLNYNTLLQAWSK
                     KINLD"
     gene            56708..58108
                     /locus_tag="PC366_000354"
     CDS             56708..58108
                     /locus_tag="PC366_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2575911.1"
                     /translation="MKNKYEEVAQLIIDGLGGKDNIIDLTHCMTRLRFILKDEKKVNA
                     DKLKSIDKVVGVNSTSTQYQVIIGNEVGVVFNAIINKGINTTGDIKSDIKNENKKNSI
                     LNNIIDTITGCMTPMIPALTASGMIKVILSLCTTFNWLSSNSSTYRVLDIIGDVAFYF
                     MPIILAINAAKKFNVNTSIAVIVVGVFLHPNFSAWVSSGDPISFIGVPIQGVIYAASV
                     IPALLTVWMMSYIEKFINKLTPSMLKTILNPTLVLLISAPIALIVIGPIGNFLGEGLA
                     SIINLLQGRLGFIMVCLLAAAMPFIVMTGMHHALTPIFISAFATTGQESLILISQVCA
                     NLAQGGATLAVALRSKDSKMKQLASAAWISAIMGITEPALYGVTLKLKKPAMLASIGA
                     GIAGLFAGITHVTLYVPQNSIMAVLGLSGEKGISNIVNGLIVIFIALVAPFIMTYVFG
                     VEKNVKESTDNVVEEV"
     gene            58425..59267
                     /locus_tag="PC366_000355"
     CDS             58425..59267
                     /locus_tag="PC366_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2575912.1"
                     /translation="MIINKILNNNVVITLDDNDEEVIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEISNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGIKLPEDEAGFIAFHI
                     VNAQLSEGHTLASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLD
                     SAHEGETDKELLSIIKSKYNKEFECVVKIKNFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNM"
     gene            59412..61340
                     /locus_tag="PC366_000356"
     CDS             59412..61340
                     /locus_tag="PC366_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2575913.1"
                     /translation="MGKYKQLAQEIVNNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDDSSTSSETKKSGNILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISAGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKFVPDLVKFFFVPMLTLLITVPVALIV
                     IGPIATFGSTLISQIVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMTIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIA
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVASPIKGEVLKLS
                     DIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDTGVEVLIHIG
                     LNTIQLEGRGFEACIKQGDRITKGQTILNFDVDAIKELGYSTVTPIVITNSSQFLDVV
                     ETESKNIELEDNLITVLF"
     gene            61401..62828
                     /gene="ascB"
                     /locus_tag="PC366_000357"
     CDS             61401..62828
                     /gene="ascB"
                     /locus_tag="PC366_000357"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDF2575914.1"
                     /translation="MSFKDDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDEHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPKGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYRGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEVDSNNLVGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGITPEMEPGDIELLNKYTVDFISFSYYNSRCVRTDENADDMAEGNIFTSA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFIVENGLGAKDIADENGYVEDDYR
                     INYLREHIKAMHDAVSIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRMKKKSFEWYKKVIASNGEDLY"
     gene            63239..64015
                     /locus_tag="PC366_000358"
     CDS             63239..64015
                     /locus_tag="PC366_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2575915.1"
                     /translation="MKYQHIIEVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQDCL
                     MCGHCAAICPTKAITLTGFDEPPIELTNKPKLDSDELLMAIKSRRSIRKFKDKEVSSE
                     IVKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSKEV
                     EIDDNFFFKHAPIAIMIITKDKISGSLAASNMALMAESYGLGVLFSGYFSDVANNSPK
                     LKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEVATVRYL"
     gene            64031..64396
                     /locus_tag="PC366_000359"
     CDS             64031..64396
                     /locus_tag="PC366_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2575916.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILIALLESDFN
                     GIRVGEITKKTHLSRPAVSHHLKILKEAEIVNLRREGTKNYYYLDSKKSQWKSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(64562..65311)
                     /locus_tag="PC366_000360"
     CDS             complement(64562..65311)
                     /locus_tag="PC366_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HDF2575917.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELISA
                     GKPFIFVCPTYAWRLPIVVTDFIKETKFLGDNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFETITPS
                     GLGGTIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNS
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            complement(65756..66313)
                     /locus_tag="PC366_000361"
     CDS             complement(65756..66313)
                     /locus_tag="PC366_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF2575918.1"
                     /translation="MRTLKYAILGLLNRNPMTGYDIVKEFNFQLAEFWNAKHSQIYPE
                     LKKLVNEKLIVYDIKISGDVLEKKLYTITEKGKDEFLKWLEKDEPMERTPKDIFRLRM
                     YFSNNLDIDTRLILLEHQLLQHQERITFLYSQMERYSEVPPLDSNDFGDYIVLDGAII
                     REQGAIKWLTNCINHHKNLDNTTLK"
     gene            66565..67863
                     /locus_tag="PC366_000362"
     CDS             66565..67863
                     /locus_tag="PC366_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HDF2575919.1"
                     /translation="MNLTQKRWIILIASCFINLCIGSIYAWSVFASPMAEHLNSLAGT
                     TFTAASLAIVFTVTNSVGPITMITGGMINDKFGPKKVVFVGGLIFGIGMILAGFSKGL
                     PMLILSYGIITGLGVGMVYGCTISNSIKFFPDKSGLVGGITTAAYGFSSVIMPPVANW
                     IINKYGVTSAFKSIGLVFLIIVCVSSFFIKKCPADFTPEGWVPPEKKGKVRVVINKNW
                     KEMLSTPIFYLMIIILTCGAFYGLMCVSLASSLATNMIGMTSSDSAIVVSILALFNTL
                     GRIVAGYISDKIGRINTLSGALVISIFGLLCLLFSREGDVATFYIGIIIIGICFGSFM
                     GIFPGFTVDKFGPKNNSVNYGIMFIGFAFAGYIGPAVMKNVYSVDGNYQRAFIIAIII
                     ALIGFILTFLYKYINKIQNLKIENLIKGDIKNGKKISKSM"
     gene            67835..69784
                     /locus_tag="PC366_000363"
     CDS             67835..69784
                     /locus_tag="PC366_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015394831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2575920.1"
                     /translation="MERKYPNLCKPIKIGNVTFKNRMFSAPMGGTDITADCTIGSKST
                     AFYELRAKGGAGAVTISECMVHPETDGSHAYHLDLKIVDSLASFTYTADAIRRHGAIP
                     SVELSHSGQYSGTYLVDKDKKRGLSQWGVSPSVRPDGLEIKELTEEIIAEIVESYGNV
                     AALAKRAGFEMIMIHGGHGWLINQFLSPYFNKRTDKYGGSLENRVRFAKEVLDSVRKA
                     VGPGFPIEFRMSGSELFEGGYDLDYGTEIAKLLESRVDLLHVSAGTYQRGFAVTHPSM
                     FLEHGCNVYLAEEIKKHVNIPVATIGALNDPEMMEEIIASGKADVIYMARALLADHEL
                     PRKVMSNQDEKIVKCLRCFTCMAERATTSTRRCTVNPLIGRELDGTEVVSVLKPKKVL
                     IAGGGPGGLQAAITAVKRGHKVILCEKTNELGGILKGEQALPFKYKMYELGNTFGKIA
                     KDLGVEVRLNTTVTKEYVENENVDALIIAVGSEPLVPPIEGLDGENVVIVNDYYVEKE
                     KVTDEVIVLGGGLAGCEAAIHLAQEEKTVHLVEMRAELAPDANIRHRPILLEEIERQG
                     IYVYTEHKGLSVTTEGVVCMNKSGNKINIPGTSVICALGQKPRREVVDTLLDSAPYVA
                     QIGDCVRASTITNAVYQGHHAALDI"
     gene            70221..70358
                     /locus_tag="PC366_000364"
     CDS             70221..70358
                     /locus_tag="PC366_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005610222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2575921.1"
                     /translation="MINENLKSLRKIHQYTQEELAEKLNVSRQSIAKWESGVSQTKGY
                     Y"
     gene            70586..70960
                     /locus_tag="PC366_000365"
     CDS             70586..70960
                     /locus_tag="PC366_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2500 domain-containing protein"
                     /protein_id="HDF2575922.1"
                     /translation="MFNLIEMLFPIMFILIFIIIVFTFVKGIATWFKNNNSPRLTVSA
                     RIVAKRQNTTHNNQPNAGDISGAHGFHTISSTSYYVTFQVDSGDRIELSVSGSEYGVL
                     AEGDKGQLTFQGTRYLTFDREN"
     gene            70976..71623
                     /locus_tag="PC366_000366"
     CDS             70976..71623
                     /locus_tag="PC366_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575923.1"
                     /translation="MNKFLSQIRRIDNEISITRKIINTIFILCFGIVLGTFAKFLDTT
                     ASNTLPFIFEYLDISNFFGRFAIWLLIALYIAIYSHSSIRASLNVLVFFIGMVSSYYL
                     YSYFVAGFFPKNYAMIWLGFTVISPLLAFICWYAKGKSKISFILSVIIIAILFNFTFI
                     YGWIYFDVYSILEVIVFGCALIALKRNTFRETTYMILSAVVIAVILNMLVPFHFG"
     gene            72003..73082
                     /locus_tag="PC366_000367"
     CDS             72003..73082
                     /locus_tag="PC366_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF2575924.1"
                     /translation="MNDMKFIETLKQKRNVCDYSQSRLAQELQINRQNLNEIENGKTK
                     ASKEMKHILLHYLDYCNCTQPFTLTIDYLRVRFPTTDALEIIKNVLAMKSEYFIHEDY
                     GMYAYEEQYIYGDISVNASKDSSMGVLLELRGMGCRDLEYVLQVRGIDWYCFLRCCID
                     YQGVFKRIDLAVNDMGGLLDIEILRERYYANKVWKRSRTHEAVDSGKLSGTHGDTAKT
                     FYIGSKNSSIYFCLYEKEKEQKSKGIKTDIKNRFEIRLKNGKAGQTVEQLVFSRNPEQ
                     TIASFILTQIDFPDYILWDIFLDNVTTSLPFIMTPVAVNMDKIKRWLERQVMPSLLMI
                     KEIEKKTGANYLEEIDRHTRLTEKQ"
     gene            73904..74117
                     /locus_tag="PC366_000368"
                     /pseudo
     CDS             73904..74117
                     /locus_tag="PC366_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
     gene            74229..75842
                     /locus_tag="PC366_000369"
     CDS             74229..75842
                     /locus_tag="PC366_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2575925.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFERPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIVEKIFSLAYQGYGSAKITKVLREEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     ATNTANKTPYSYYACSYYGQFGKGTCSMHYIRYDVLYQAVLKRLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASAFKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITNLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEAITNEDNERIQEIEIYYRFIGKVD"
     gene            75871..76194
                     /locus_tag="PC366_000370"
                     /pseudo
     CDS             75871..76194
                     /locus_tag="PC366_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861830.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
     gene            76226..77413
                     /locus_tag="PC366_000371"
     CDS             76226..77413
                     /locus_tag="PC366_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HDF2575926.1"
                     /translation="MSKIVFFSILAYGHTNPTIEVVRELVDRGNEVLYYSFNEFKDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPGLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQNFIEIIRMIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIK
                     PKERKRKLIYISLGTINNKNVSFYKNCINAFKDSDVDVIMSVGRSTDIKSLGNIPNNF
                     EVKNSVEQIAILQKTDVFITHSGMNSVNESLYYGVPMVLFPQHSEQRMVAKRVVHLGA
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            77605..78009
                     /locus_tag="PC366_000372"
     CDS             77605..78009
                     /locus_tag="PC366_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HDF2575927.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNCIKPWKDAETYIDKYMVK
                     QDISKDNIKSITKEKAKKASYEGILYKVYYKDDPRYEYQYFYSDNYHALYVNKVMLQI
                     YDVENNNKLLRSNEELKSVKYPPIYLKYKPDK"
     gene            78579..79439
                     /locus_tag="PC366_000373"
     CDS             78579..79439
                     /locus_tag="PC366_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2575928.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKALNIKSSDYLSLTLLDHLEF
                     LLKRCEKNQFIKSPLVWNVKRFYPKHFEIGMHALKLIGDSKGINLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVELDETSTNYMRFTTHLQYFIQRIMSD
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
     gene            79429..81300
                     /locus_tag="PC366_000374"
     CDS             79429..81300
                     /locus_tag="PC366_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2575929.1"
                     /translation="MKYKDLNENIIKLIGGKENIKSVAHCVTRLRLTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSIKSERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASILALLNMSGILQSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQATTYANSFIPI
                     LLGVWAMGIIIEGLKKILPKALHYFLVPVLSLIITLSVTLTVFGPIGMWIGDGLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPISLNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGI
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEASNFTFMIISVVVSFVAATAASYLLGIP
                     SDEKEEVKGDNEKELELIINENNSRTISIGNVAKGQVIALGEVNDKAFSSGALGKGVG
                     VIPSESKSTVISPVDGTITIVFPTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFESDKIIEEGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            81320..82774
                     /locus_tag="PC366_000375"
     CDS             81320..82774
                     /locus_tag="PC366_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDF2575930.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDNKGPAIMDFVTKGSYETPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYEGLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLMDLYLKYSETVI
                     RRFDDKVKYWITFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKVGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNITIEVTDEDKKAFKEGKLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPIGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDDY
                     RIEYLSKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKSNGEVLDFSTDIVVG"
     gene            83798..85006
                     /locus_tag="PC366_000376"
     CDS             83798..85006
                     /locus_tag="PC366_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575931.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLL
                     GFWTNVLPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALVGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFRLPSMRIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIVPTIGILVVGSVFIILFTAIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
     gene            85037..86416
                     /locus_tag="PC366_000377"
     CDS             85037..86416
                     /locus_tag="PC366_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2575932.1"
                     /translation="MIGSISINEIDKKRFKLDDLSKKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEVGVGGLATAIRASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELSAY
                     GHGCGHNLLCTAHVGAVVGLKREMLENNLSGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYTRALSREAVESTYERLVKVAKG
                     AAMMTETEVEVEFLGGCYNTLNNHVLANLVSECMNEIKQEPWTREELDFAAELDRQSP
                     QQYKAMISKYNLPEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYASKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            86522..87712
                     /locus_tag="PC366_000378"
     CDS             86522..87712
                     /locus_tag="PC366_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2575933.1"
                     /translation="MKNFFKEAQSIEGEIIRWRRYLHENPEIGCNLPKTVTFVTSTLE
                     KMGYSPKLTSNNGIVAVLDSENGGKTLLLRADMDALPIMEETDLPFKSKNKDASHSCG
                     HDNHTAMLLGAAKILMDNKHLLKGRVKFVFEPDEESTRGAKSMIDDGILENPQVDAAM
                     AFHSMVGKFLNTGQVAYSRGPAMASADIFEITVEGKATHGASPEFGVDPINIMSHIQI
                     ALNTILSREKPQKEPVVLTIGMFNAGNVPNAIPNKASMSGTLRTFDQFVREKLKNRII
                     EISTGIAKSFGGNAKVEFKMGTPAVINDLDVGDEIVSYVKEIIGNENVIDFPSAMGSE
                     DFSEILLRVPGVFLWIGMGSISQGYNFGMHNPKAIFNEEGLVYGSALFAHCAVKWLEN
                     NFSR"
     gene            complement(87840..88904)
                     /locus_tag="PC366_000379"
     CDS             complement(87840..88904)
                     /locus_tag="PC366_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575934.1"
                     /translation="MFLKLIFKYNTLDFSRAYFDLTDWADNPKDISYYLSNGTFGDLM
                     DSIDENASKMSLSDIAKLEKKIAKKHINLWNEGKIDFSTTRFSSIVPMLQNAGVNFHF
                     IYPDIDLLKNTFNNLIKDIHLHRMKGNQPSVIYITVKDTNYDDSTLDQVYKILNSIKK
                     DKLTDFIIEKNSNSFKIFTKCETIKSLTKNFTACYIKESIENSTNIKVCVGYGIGNDI
                     KQAMSSAISANKESKINPLNYSFLVNENYETIGPLLCDKLLTVSNKVTPHINTIAKSS
                     KLSTLTIQKIISVTEILQRDEVTPKELSSCLNVTVRTANRFLSSLLKSGNATILYEKQ
                     NSTKGRPERVYKLFISENKY"
     gene            complement(89052..>89456)
                     /locus_tag="PC366_000380"
     CDS             complement(89052..>89456)
                     /locus_tag="PC366_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2575935.1"
                     /translation="RLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNMIKNRRL
                     SRLISDVSWSEFIRQLEYKANWHGRKIVKVGKFFASSQICNKCGYKNEEVKDLNIREW
                     ICPSCNETHDRDINASINILKEGLRLITIQNK"
BASE COUNT        35540 a         9707 c        14980 g        29229 t
ORIGIN      
        1 atttataata tgtaatattt ttgttttgaa atttagaaat cagtgttact ggttaaagtt
       61 agtttagtat taagtatatt cgaagtagtt ttttagctat tttcatatct ttatattact
      121 taattatata tagcctaact aacttaatat atcagtgaaa tattgactaa aatgcctaaa
      181 tatgttatca tacaagttag tcaaataatt tggcaacatt aaatatttag taaatttcta
      241 acatttatgg aataaatttc taacaaagaa ggtgagattt atatggctgg taaaaaaata
      301 ttagcaacaa acaaaagagc aagacatgaa tattttatag aagaaactta tgaatgtgga
      361 attgaattaa aaggaacaga agtaaaatca ataagacaag gcaaagttaa cctaagtgat
      421 ggatttgcat ctgtagataa tagtgaagta tttttaaaac aagttcatat aagtccatat
      481 gagcaaggaa atatattcaa tgttgattct ttaagagtta gaaaactatt acttcataag
      541 catgaaataa gaaaacttat tggagcaact actataaagg ggtattcact tataccactt
      601 agtttgtatc taaaaaacgg taaagttaaa gtagagattg ccttagcaaa aggtaaaaaa
      661 ctatatgata aacgtcaaga tatggctaag aaagatgcac aaagacgtat agaaagagaa
      721 atgacaggta agtattaaac tagataaaac tgtatttttt agaataaaat tctttattat
      781 ctagaacata acattgattt ttattcttaa aagtattata ttatatatac attaaaaatt
      841 taataaaaat ggtgataaag tttgcgaaaa gtctactgga ctataaacta ctcaaggggg
      901 cgtaaaggtt tcgacgtggg tttggaactt gaggctgcat gtcgtgttac tctgggtcac
      961 gtaaaaactg gggaacttta aaataaacgc agacgataat ttcgcgatag cagcctagtt
     1021 gctgctcgtc cctcttagtc ctcctgccga ctaagactgg acgtcattat gcagggaact
     1081 actttagggg tgtctcgacc tgaagtagat taattgggac tggctaagca tagagcctgc
     1141 cacttggcgc tatgtgaggt gagatattag tgaagttggc taagcatgta gatgcagcaa
     1201 ggaaaagatt tgcggacagg ggttcgactc ccctcgtctc caccaatttt taaaaaagaa
     1261 tgatgaaata cttggaaata ctagtcttta ttgactagtg ttttttgttt tggagatgaa
     1321 atccaccaac cgtgccccaa ccacagaaaa agagattttt ttggggtata ttggggtgca
     1381 tttgattaat ccatggaaca tataaagaat acttttagag atatagtgaa tttgatgata
     1441 atacaataaa tattttatac tgatgaattg tttttatatt atgcttttta tttcaatcta
     1501 ggaaatatat aacttgttta aacttatgat taaaaggata aagaagttta aagcatataa
     1561 gtgctactta atctattaga gtaattacta gttataatga tatacagaat cctataagat
     1621 tatgtataag tatagaacaa atttattatc tatgtgggat gctaatttaa attttttaat
     1681 tgtatttaaa aaaataagat gtaaaaaagg aattgaaaaa tgttaagata ataaacacat
     1741 agaattatta agtttaatac taacaagact attgtatata gacaatatat tatatataaa
     1801 atttaaataa tatatcataa aagtacctat actaataagt acttttatga tataagttaa
     1861 ttctattttt ataatataaa ttaaaagtat ttaaagcgtt gttaaaggct atagtctatt
     1921 attcatcata ttcgatttcg agctgtacag gtagattgaa agctctatta aaaagcacat
     1981 tgaaatcttt ccagtctttt gatgcttgca ttaaggttat aacctttaat aaatgatttt
     2041 ttaaatgatc attacctata tcttctgtta aaaattgatg atgtttatgt tttctttgcc
     2101 caggttttac tgtggggtta actctttgaa gttcttcttt aactccagga ggtaataaat
     2161 cataaacata tttatttgtg tatgttccaa ctattccagg tctcttagaa cttggtctag
     2221 ggtatgtcca gttttttaat ctgaacattt gtctataaaa ttcatcagga aatctttttg
     2281 tccaaggtaa aaactcttta gaaatataca tagacaatat tttttgcagc tcatcacgat
     2341 ctctatcata ttgatatcct gtagcttcat caactaatgc tacaatccct attttggata
     2401 aacttcttac taaaatttcg cttgctatag ctagtccttc ttgctgaaca gctaatttat
     2461 tatcaagcct tgcttgtaaa tatacatcac atataagagg tattatttca gctggataac
     2521 cttccacaat tcttccgttt ttagtcttat attttattgt atttataagc atatcttcta
     2581 attcatctga aatataatca gatagattct ttgcatcaat aaaacttggt agattaggct
     2641 tagaaggtac acgaatttca tctttttttc taccacgctt tgttcttcca aaagctttga
     2701 atactgtact tttatttatg attcttgaac cattttctag tacagcacaa tttaaatctt
     2761 tttcacctat ttttataata ccaaaatgtg ttgctctcaa tatacttttt tcttttgatt
     2821 ccaatttaac accatccttt attttatttt aataagtaag atattactta gtatctcttc
     2881 attagataaa ttagtattta taagactaat aatatcaatt ttaaaatatg tatatagata
     2941 attgagtttt tttatcatct tgtacgcagt atttttatta acaacgatat tttttgataa
     3001 ttttctatag ctaatatttt catcaaatat aaataaatta atagcaagta gccattttct
     3061 gtagtctagt ttagttttat gcataatggt attagttgta attgaaaact tactattgca
     3121 aatattgcaa tgaaataaat cattataagt actaatttta tcagaataac aataggggca
     3181 tattaatgag ttttttaatt taagattata taaaaaaatc ttataagaga catctgttgg
     3241 aaagttttta taaatatcaa agtcttttgt cataatttaa ttatatcatg ttgtagaaat
     3301 taatttactg tatttaagtg ggtcaaattt aatatatatg tttttgatag tgtaaaaatt
     3361 aaaatataat tttaggcatg tttgtattga ataatgagca ctttcaaatt ttattagtgt
     3421 aagaggtttc aaattataaa gtaatgaatg tatattacta tatgatttat aattagaata
     3481 aaatttttat aatagaaatt taatatatca aaatatcagt tgaggatatt gttcaagtgg
     3541 tatatcttcc ctgagttaaa aaataaatga tgaaatattt ggaaatgcta gtctttattt
     3601 gtttatgata ttatgtaaca tagaatttta atatctactt tatgatataa tatttttata
     3661 aacataagat ggtttaagtt attaattaat aaaaatatat atattatata agtggatagg
     3721 agttgaggtt tgtaatggat gaaagaaaac tagaattttc tattttttgc attgaagctt
     3781 tagcagaaaa gttgaatata gattcagaag gagtttataa acttcttaaa catgatactg
     3841 atattttaga taactatata ataccttgct atgaagcact acattctcaa agtaaaagtt
     3901 atatagtgga agatttaata caagtgcttg aagaaaaggg cgtgatgtaa taattgtata
     3961 tcatgattca tactgtgtgg caaaaacgcc taatattatc ttcttaagag attctttaga
     4021 ttttggaaaa ggattctatg taaccagtat aaaaacacag gcaattaact ggatagaacg
     4081 ttttaagaaa aggggtaaaa aagcatattt aaatagctat tctctagata ttgataaatt
     4141 aaaagaaaac tgcaaggtaa aaatcttcaa tagttataat ttagaatggc ttgactttat
     4201 attagaatgt agaaatatga gtgatgtata tatgaaatat gatgttataa taggtggaat
     4261 tgctgatgat aagatttaca atacaataga actgtatcaa gataatctta ttgaaaaaga
     4321 tgaagcttta aaaagattaa aatactataa gccaaatgaa caaatatgta taactaatca
     4381 aaatgtaata gataaatatt taaagtttag atgtgaagag gaggtatagt gcttatggaa
     4441 gcaaataaaa cattattaca gatactatat aaaaaaatta tattagaatt ttctaatcag
     4501 acaggcaaga gtttggaaga aagtatggat tatttatata cttctgaaac atataaactt
     4561 ataagtgagg gtgtatcaga tatgcactgt aagggtcata tatacttggc tcaagaatta
     4621 atgctagaaa atggattaat gtatcataaa ggctatccaa gataaatagt taaaactaga
     4681 tacgaattaa ggatacaaga taatataaaa ttaatttgta tccttatttg ggttttgtaa
     4741 ttaactatat gaaatcatag tatttttatg tatttgattt ttacaatgaa aatattttat
     4801 ccaacttttc tacagcttca accttcttat cttccataac ttgagtatat atatttaaag
     4861 ttattgatat atcataatga cccattaaaa cttgtacagt tttaggagga acatcattct
     4921 caaaaagtct agttgcataa gtttttctaa gaccatgaaa ctttataggt tctatatcta
     4981 agctgcttaa tatagatttt aaattcctta aaggtctttt atcatctata gggacaccta
     5041 attcattgca aaatacataa ttatcatttc tatataattc tccagccttt aatatatcca
     5101 cattttgatt tactttatgc tctttcaatt tatttaaaac atcttttgga ataggtacag
     5161 tcctgtaaga atttgatgtc tttggttctt gctctaatac tttaagctct ctatttccat
     5221 ttttatctat aaaatatgtt ctttgaaggg ttcttttaac tgttaaatta gaatttttaa
     5281 aatcaatatc aaaccattta agtcctaata attctcctaa tctaagtcca gtaccaagag
     5341 caaccaaaaa taatacttct aatttatgcc cctctatagc ttttataaaa ttcttttgtt
     5401 gttcaagagt caatatttca agcctatttt cctttttctc aactggtata tttaccatag
     5461 tacaataatt acgttgtata agaccttgtt tttcagcttc tgataagcag gttttcagtt
     5521 tagtgtttat ttgccttata gtaggtatac ttttattgga atcaagcaat ctattgtaat
     5581 atttttgcat gtgagatact cttaagtcct ttaacttaac attgcctaaa tcagtatctt
     5641 taatataatt acgatagatg ctttcatatc tttcaaatga ctttggtttt aaatctttta
     5701 ttctatattc aaacaaccaa ttgtaaaacc aatgctctaa agttatttta tcatctgaaa
     5761 tatcagaact taaataatat tgttttttat aagcatcaag tttatcttta acttcctttt
     5821 gagttttacc ataaaattct tttcttattg gttttccatc ttcattataa ccaatcatta
     5881 tacgagaacg ccaaccatct ttatattttc cgatagagcc ttctccatta gctcttttag
     5941 ttgccatttt taaacaactc cttatatgat ttatagttat atccatcgaa gaatgtaata
     6001 catttctcta ataagaattt tataacttca tcagcttcta gtgtttcata gaagtttagc
     6061 attaatgtgt tgtattcttg tttatgtttg gctggtattg atagaactcc tatatcatta
     6121 cttataagta ttaggtttga ggtaagtcga gcagttcttt tgttaccatc atagaagaat
     6181 tgacaatagg acaaccataa atttattatt atagcctttt ctaaggggtt agttatttta
     6241 tttatgatac ttatgtcact tataaataaa ttatttaata gagtggcttc tatgcactca
     6301 tattgagtag taccagctat acctatgtta ccgtttctaa aatctccaac aattagagct
     6361 tcatcttttg caactatttt atgtatagag caaattgtat ctttatttaa agataagttt
     6421 tctttgttac ttaattttat tatataatcc catgatgatt ttatatttag tatttgattt
     6481 tggtcactta atttatgtcc acctactgtt ataccatcaa gtaatgtttg tacttctggg
     6541 aatgtgaagg ggttattttc taggttaccc atatcatata caaattcact tatcattctt
     6601 ctaatgtatg ttaaagtata ctttttatct ccatgaggta gattcgtagg gaatttatgt
     6661 gtgtattttg gtatatatga tttattcatg attttagctc ctttcatatc taatttttat
     6721 ttattaacta tgaatgtata aaagttaata ggtaaaccca tattttgaaa atgtgcaata
     6781 ctaatattct tcatcctcat cttcaataag accattagag ttttcttgta taaaattttc
     6841 aacaagacca tttatcaccc aatttagatt tttggagaag tctttgaagt cagagaagct
     6901 taagctaatt ggttttattg tatctgcatt atctgtaatt tcaaactttt ttttatagtc
     6961 tgtttttata tcataaccat aattttctaa tatgtgaact actaaatcca actctttatc
     7021 aaatactttt aaattaatat tattatttgt taaagtatct aaatcatttt cttcaacaat
     7081 gagtttattt atggcaattg ataaagcagt agatattttt cttatcatat ctagactagg
     7141 tattctttga ttttgctcat atttagctat agcatgaact gaacaaccaa tcttgttggc
     7201 tagctcattc cttgacatat ttatcgattt cctatattgt ttaatctttt ctccgattgt
     7261 attatttatc ataattccac cttaaatata tcatcaaaca atgattgtat ttttacacat
     7321 ataaaggagt tattttctag attatctata tcatatacta acttactcat aattctttta
     7381 atgtatgtta gagtatattt tttatctcca taaaataaat tagtagggta tttatatgtg
     7441 tattttagca tatatgcttt attaataatt gtaactccat ttgtagtttt ttatcattgc
     7501 tttagatagt attgatatta ttttatattt tagttagtag tttttttatt tctttaagtg
     7561 tattttcaag ctttttattt ttttccttta attcattatt ttcttgtaat aatttaaagt
     7621 aatcattatt tttaatagtc atattttctt tttgagatat taactttttt agtcgaatgt
     7681 tactcccatt atctgttgcc tcactaaagt aatcatagat tgcttctata ttttcttctg
     7741 atagaccaat atctaataat tcatcaattg attgttttat aagaacatca tttttaataa
     7801 tttcttttat atcatcagga tgtaatgaaa aatctaattc agtattagat acacaatctg
     7861 aaagtatcca attataaact tgattttcat ttagttctaa tttttcacca agtttataat
     7921 attggtcttt atcagaccaa gcacctagca ataaacttga ggtaatccta atatcatcat
     7981 cttccataag atttgaaata gcatttaaaa attcatcaaa agaatagtat tcttctggga
     8041 ataaagactg taaaaaatat aaaacatctt cattagtcat tacttcattt tcaatatcaa
     8101 aataaaagat agtcttttca atttttaaag ctttagcgag ttttgataag gtatctatac
     8161 taggtattct tttatcattt tcataattta ttagagcatt tcttgagatg ccactaattt
     8221 cagcaagttg aatctgtgtt agttcttttt gttttcttat cttttttaag ttttttccaa
     8281 tttgcaatat tatcacctcg tataaagtat atcccaaaag tacacaaatg agaacagaaa
     8341 aataatatat tcttattgac agcacacata tgtcgacatt ataattaaaa tgtaaagttt
     8401 acgaatgtaa actagaaaaa aggaggaaaa agtatgggaa tcaatttaaa aatatttagg
     8461 attaaaaaag gtttaaagca acaagaactg gcagatagag ttggtatatc aagatattat
     8521 ttgtcaaact tggaaacagg taaggctaat aatccaagca atgatttgat gattaaacta
     8581 tctagagctt tagatacaac agtagaagaa ttatttttta gtaaggagga gtaaaatatg
     8641 aaagagaata ataatttaga agttttaaag acattacaag ctactttaaa cattattgta
     8701 aagaatgaag aagaagcaca agaaaaaaag caaggatata aaattattga aaatgcgaaa
     8761 agaaataaag ctgaacttat aacatgtaaa gaagcatcta agctttatcc tataggagaa
     8821 tcaaaattta ggcagttatg tcactctaaa aataaaggtt tcccttgtat atggataaat
     8881 aatcgagtat acataataaa aaacaaattg gatgattggt ttattgaaaa tgcaaatggt
     8941 atcaagttat agtcttaaag taggtgtttg caattgagca ataaagggtg gataaagctt
     9001 tacagggagt tgttggataa atcaatttgg aaagatatta aaccagaaag aaaagtaata
     9061 ttaataactc tattacttat ggctagtcat aaagaaaatc atgtttttat agataataaa
     9121 aggataaaaa taaagtctgg acaatttatt tcttcttata gcaaaatagc tgaaagatgt
     9181 ggtaaaggag ttagttatca aatggttaga agttgtttgt tggtttttaa aaatgctggt
     9241 tttctaacat acgaaacaac aaacaaatat atagtcataa ctattgaaaa ctgggagctt
     9301 taccaagaga acatagaaaa tcaacaacct aatcaacaga cgattaacaa tcaatcaaca
     9361 acaatcaaga atataaagaa tgaaaataat attatatata gtgaaattat aagcaaattt
     9421 aactcaactt gtattgaact ttcaaaggtc aagaaactaa cagacacaag aaagaggaga
     9481 ataaattcaa taataagaga atatgataaa gaagctgtat tagaggttat aaatatagtt
     9541 agtaaaacaa gttttctgaa tggaaataat aatacaggat ggaaagcaaa ttttgattgg
     9601 ataatgaatt caagtaattt taccaagata ctagagggca attatcatag caaggaaatt
     9661 gtcataaata aagagacagg aatatataat ccagatgatt cacaattaaa gtggtaagga
     9721 ggttatatta taaataattc aaacaactta attaaaaata cagaagcaga gcaatcaata
     9781 ttaggaagca ttttattaga ctcaacaata gtagaagagt tagagcaaat gttaaatgaa
     9841 gacatgtttt atcatgagga acataaatac atatttaatg ctataaaaga aataaataag
     9901 agaaatgaag taatagatat aataactctt acagaagaat taaagagaaa aggtcatttg
     9961 aataatattg gaggtataag ctatattacc agtttgtcaa caatagtccc aacagtatca
    10021 aatttcacga gttatgtcag tatagttatt gaaaaatata aaaatagaaa tataattgat
    10081 aaattcaata agttcaatct tggagaaata gatgataata ctcttatata tcagttagaa
    10141 aatgatataa ataaagccaa tcagaaatta ataaaaaagg attcaagtat aacagccata
    10201 tcagagagag cctttgaata tataaatgat gaaatgaatg aaggtattaa gactggaata
    10261 aagttcttag atgatactat aggaggttta tatggaggtg aactaactac aatagcagcc
    10321 aaaagtggaa gggggaaaac agcattagct ttacaaatac ttagaaatgt aatatttcaa
    10381 ggaaagaaag tactttttat aagtggagaa atgagtgata tacagattct gtttagaaat
    10441 atagcctcac taactggaat atcagttgta aaaatgaaaa atagaaatct aaatgatgat
    10501 gaaatagtca aatatataca agctttaagc ataataaatc aagaaaataa cctttatata
    10561 aatgactctg taaatacagt atcagggata aagagagaaa taaagagtac taagcctagc
    10621 ttagtcataa ttgattattt gcaaattttg gattatgaag gtaaagaagt aggagaagct
    10681 aaatttgctg acttatcaag gcaaataaaa aagattactt tagattttaa tataccagtt
    10741 attcagcttg ctcaattaaa tgatgaattg aaggatgaaa gacctaaagg ggatagagta
    10801 atgagaagct caaagcagat atatatggat tctaattcag ttatatatat tcatagacct
    10861 acagaaaaag aggctcttaa ttattgcaag acaatgggaa ttgaggatat aagagagttg
    10921 agacgaagag aaaaaggttt tggtgctaat ttaagtgaga ttattgttgc caaaaataga
    10981 gatggtgagt caggatttag accatattgg tatataggaa atttgttttc ttttgaagaa
    11041 tgtaagaaga tacaagagat ataaaaaaga agcatgattt attaagtaat agataaatta
    11101 tgtttcaaga agtattgaat ggtaaatata taaaacttaa ttagatgtaa tagagattta
    11161 aaatatattg agtttagatt taaatgctta ttagaaaaag gtagttgcca tataaatata
    11221 acaactacct ttataaatta ggtacttaat gtacactaac ctagcaactt aagtatatat
    11281 taagtacctg atgaaagtca aggaggtact aaaatgtatg atgaaattat agaaatatat
    11341 tttgattatt ggataaatga acatatgtat agaagtattt tagaaaaaga tgagtattat
    11401 attgaatgtt ggaaagaggt taaaaaaatt aatgagttat tggaaataaa tttggaagat
    11461 gataagaaat atctgttggt tgaattaaat gatttgttta attcattaat agaatttgaa
    11521 agagaactta gttataaatt aggatttaaa acaggagcaa aatttataat agagttgttg
    11581 aagtaattaa tttgtgtatc tcaatagaat aattaaatag taaatcgaga ttattaataa
    11641 gttgtactag aatattttaa gtgaagtata tattaattat attgtttaaa ataaatatat
    11701 ttaataaaga ggggataagt atgccctctt ttatttttat gcaatcaatg acattgtagg
    11761 atttacgtat tttgataaat agcacaatat attttaataa taaatatatg atacaataat
    11821 tttattaaaa tctaaaataa tcaattgagg aggagaatat gataatacct aagttagagc
    11881 ctaatgatag aaaaagagag tttaataaat actcatcaga gcaaataaac aaagtagttt
    11941 ataattattt atttaaaaat aatatgagta atagaaagat agatgatgag atactagatt
    12001 tatcatcaaa acaaagtaaa ggttatcaat caatgggtat agtgcatcat ttaggaataa
    12061 ataaaaatca taaaggtatt tttacaggat acacaataga taaagcaatt gaagttctta
    12121 aggaagatga gatacatttc aagcagatta ttaatatact tttagaaatt agaaatataa
    12181 atgagtatcc tataatagtt gactcttggg agttattaga tgagaaaata gctttaaaaa
    12241 caattgataa atctacatta aaacataatg ggacaggagt tccaatagaa ataagatatt
    12301 tttttgagat aaataattta ggaaagaatg aaaagaaaaa tgtgaatttt aaatataatg
    12361 ataattatta tagtgcagtt atagagatgg ataaattaga gaatccaaga agtagaataa
    12421 tttggaaatc taagtttaga gatttactaa gaagtatatt ttctgagtat tatgagaaat
    12481 tcttagaaaa taaaatagaa ggaaaaacaa atttacctaa aataagattc ataaaacttg
    12541 atagtaataa ttttaacata gaattcattt ttactgctga aatagaagac gatgtattag
    12601 aggagataag tcaagataat cctttgaaca ttaatactat taatatagaa ttagaaactg
    12661 aaattagaaa agaagggaaa gttaaatatg tttatgggaa acagtatgag cgtaacccca
    12721 gaaatagaat agaagcaata aaatatcatg gcacaaagtg tattgtatgt gggtttgact
    12781 tcgaaaaaac gtatggagat agaggtaagg gatacataga aattcatcat attaaaccat
    12841 taagttctgt tggagaagaa agcaatataa atcccaaaac agatttggtg ccaatatgtt
    12901 caaattgtca tagaatgatt cacaggaaga aagataatgt tttgagtatt gatgatttga
    12961 agcaaattat aaaagatagt aaataatgct tatgtgtggc agagatgtat aaagtatata
    13021 ttctaaacta gttaacaaca aatactaata taaaaaatca aaaaatttat taggaaaagg
    13081 tagttgctaa agtataacag ctacttttat aaattaagta tttgaggtat attagtctaa
    13141 ccgattaggt atatcttaag ttattgatga aaattaatta agactaacat gtatgatgaa
    13201 tccatagaaa tgtattttta ttgttaaata aatgaacata catagaaata ttttagaaaa
    13261 ttacaagtac tatattgaaa gtttgaagga gaaccttgat ttaaggtaag tgtaaagttt
    13321 ttagaaactt cactaaaata atctaattaa gttatatatt tgttactttt aggaaaataa
    13381 tggtaaaaat taaaggtttt tataaatgaa tgtctaattt tataaataaa atggagtatt
    13441 ttaactaaat atttgaggag ataaaatgat attaaataaa atcgaaataa ttggagatat
    13501 ggctcacttt aaaattccta tgcatagcaa gatacaaaga acatatgaaa ttccaccaat
    13561 atcaacagtt gtcggaattt taaaaaatat atatggtgaa gaaatagatg attttatatt
    13621 aggatatgtt atatatcatg atggtacatt taaagattta cagactatat ataaagaaat
    13681 caatccaaat gtaaaaacat tgacagatag cgatagattt caaactgatg tatgtcccat
    13741 tgaataccta attaatccta aacttatcat atatactaac atagataaaa atatagaatt
    13801 taatgagccg ctatgtttag gtaagactaa ttgtttagcg aaggtattat ctttaagtga
    13861 aattgaagta aatctaatag ataaaaaagc tattggatac aatcaatata cagatattaa
    13921 tattggagat ggaatgataa aaagaataaa tacattgaca gagtataatg aaaaaaaagg
    13981 ttattatgat atatattctt caatggtaag agaaaatgat gagtttgaat atggtaaata
    14041 ttatgatgaa gatgagcaac agaatatttt tttatggaaa tggaaaaaag ggggagtaat
    14101 taaatgcatt tagtaagaag acatttgata ctcacagtgg ataatgaagt tgtattagat
    14161 tacaattacc agtatgagct aatgaaaagg atatatgaag ctatagaaat taatgataaa
    14221 agaaaagcac taagtcttca caatgaaggc tataaggtgg ataagaaagt atttaaatta
    14281 tttaattaca caattatgtt tgaaaatgct aagtatttaa aagagggaat acatttaaat
    14341 ccccaaacaa aaatcaaatt aattttaagt ggatatgatg atatattgaa taatattata
    14401 aaaggtttta ttaaatgtaa agtatttaaa ttgaataata tagagtttaa agtttcagat
    14461 atagaagaag attcaaagaa aaattttaat aatataacac tttataaagt aaggtcacct
    14521 attgtagcaa gtttatatga tttaaaaagt aggaaacaag tatacttaaa tccaatgcaa
    14581 gaagagtttt ataaagcatt acatgataat ttaggaaata agtataagct tatacataat
    14641 aaagaatata ctggtgaact atactttgat attgaggatg tattagcagt aaaaaagaaa
    14701 tatataacta atataaaagg aaaaggattt ataattggat atacagattt tgaaatattt
    14761 gtacaagcta ataaagatat gcaagaagta atttattatt gtggattagg tgaaaaaaat
    14821 agtataggaa tggggttact aacttatata acttctagga gggcttaata tggatagaag
    14881 ttacaatgta tttgttgata atggtctata tgtgttggct tattatctga acaaagatat
    14941 taatgatata acttatcaag atatagagaa tagtatagat ttaatgagtg ataaaattga
    15001 agaatttgta agttgcgaaa aatactctaa tttaaaaagt atgtgcttta gcaattctac
    15061 gctaactcaa ccaaaaggaa aagttacttt aaatgagaag ttaaaaggtt ttgttaaaaa
    15121 tcaaggagat gaatattgta gtttatgtgg tcaatataag gccaaagtca aaattgaaga
    15181 taaagaatac aatataggga gaagttatat gcctaatttg gttgcaaata cattttataa
    15241 tttctccaat aatttgcaag gtttgaatgt atgtccatat tgtttagtat tgactatgta
    15301 ttcaattctg aattgtagag taagtaggta tgctttttta tacaattcta catcaagcga
    15361 atttatggaa gattatactt tccatattca aaaagaaaat ttaactgatg tagagttagg
    15421 agcaaagaaa gaaaaagaaa agtattcaat tgtaaaatta ttagaaagtc tagtgtgtaa
    15481 atataactta tttaatggtg atatagagca atatatgttt aataactctg gtcaatctca
    15541 ggatattcag gtaaatagaa taaaaaataa atatgtgaat ttattaataa aattacagga
    15601 aaaagcacta ctatcaaact ttgaaaagtt acatttggat aggtatatct tgaatggtac
    15661 tttagaaagc aattatctca gagaagtata tagggtaaaa aaggaagaaa aaatggatga
    15721 gaaagaacaa aagaattttg atgaacttgt tattttttta aacagggagg taaatgtatt
    15781 gaaaaaagtc aaaatagata taataaaaaa attaacggat aaattaaaaa ctagtgactt
    15841 agatatagac aaaatatata aggagcttaa aatgttagga aaattttatg catatgagga
    15901 ctggttagtt aacttaaatg aaatgtatta tgaaaaaact ggagaaaaac tatttgaagc
    15961 agaggattat attgagttgg atgatataag aagctttaga cagattaaaa atttaatatt
    16021 agtaagttta atttaataat attatggagg gttaaaatgg aaaataaaaa ttcaaataga
    16081 atgttaaata taggctatgc aatagaagtt ttatgtgggc gattaaatgg aagtagtagt
    16141 gaagtagaaa agaaaaataa ttcatataag aattctactt atactaaaaa aatagggagc
    16201 agaagtagaa tctcaagtca atgtcaaaaa tacaatcaaa agctatttat ggaacaagtt
    16261 tgtggttatg aacaaaatgt taaaactaaa gatgggaaac aagtaaaatt ggttccaaac
    16321 ccatttaaat atgcgacaga tgatatattt gggtttatga tggcggaaaa attatctata
    16381 gaagaagatg tatacaaaga attatcagat gaagaaaaag aaatatataa aaaaaataaa
    16441 aagaaatatg aagtaaatat aactaaaaaa agaaagtcaa gatggcaaat gaactcttta
    16501 ataaatgtat caaatagaaa agttgaatgg gagtggaatg tttgtggaac tacaggagat
    16561 agtatgccat atcaagttga ggtatattca ggggtacata caaatatagc aaatcttaat
    16621 ataggaaaga taggagaata tgatatatct gatatagcaa gtgagcatag agattataca
    16681 actttagaag ctaaatcaat tggagttgaa aagttagata aagaagaaaa gtttaaaaga
    16741 atagaagctc tcctaaaatc actagaatac ttaagtgtag aaggtaataa gacaaatcat
    16801 ctaactgata caaaacccaa atttgttata ttgggagagt attcatgggg aaataatgta
    16861 tttcagggta ttatcaaaga aaatggctta gatgtagaga tgttaaaaga atctatagaa
    16921 caaaatgaag aatttagaaa aagcgatata tggattggaa taaataaatt ttatgatgat
    16981 acatttaatg agatagaagt taataatgaa aaggaacaaa taaagaagta tttagaagaa
    17041 gagtttgaag agtatgattt tatgaaaata tcaaatgtac atcaagcttt tgaaagttac
    17101 ttaaaatatt taaaggagac tttataaagg atatatcatg aataatttat atgaatataa
    17161 agctaaatca gatgggacaa gtatagataa gcataatgaa gatatgaatt acataatgaa
    17221 tcaattagtt agcatatata atatatctaa tgatatgaaa aatgatttat atgaggcaat
    17281 tgtatgtcat gatgtaggga aagtagtaaa aagctttcaa gataatattg aaagtagcac
    17341 aagaagagtt agacatgagt tattatcagc aagtattaag tatttaaata gaggtcagaa
    17401 gttagctata ttaacccacc ataaagatat aaagtttcta gagggtcaaa taacaaattc
    17461 tatttatgaa attgaattaa aggaattaaa ggaactatta gatattgaag tagaagatat
    17521 aagaccattt ataaaggaaa tatcaagagc aagaaatgat gatactagaa aacttgaaaa
    17581 tatattatta aaaggttact tgcaatattg tgaccatata gcttctgcgg gaattaaaag
    17641 tatagataaa ggatttaatt ctattaaaga ttttagtata ccaaagggtg taagttataa
    17701 ttcaatacaa gaaaaagttt taaatatgga taaaaatgaa gatataatga taatggctat
    17761 gacaggtctt ggaaaaacag caacatcatt gtattggagt aacctagttc aaaatgaata
    17821 taaaagtaag agagtgtatt atatacttcc ttatacagca agcataaatt ctttatatga
    17881 aaatttatat aatagaaata taagcgtaag tatgttacac agtaaagctc catatttttt
    17941 gaataaaatt agtgatgaag aagatataaa acaactttac cagatataca aaaagagtgt
    18001 aaaacaaatt aatgtatgta ctatatttca attagtaaag tcagtatttt cttgtaagag
    18061 atttgaaatg ctactatcac aattaaaaga tagtatattt atagttgatg aaatacattg
    18121 ttttgataca agagtattgt gttatacatt ggaattttta aaatatttaa aagaaaactt
    18181 aaatgtaaaa atatgtataa tgagtgcaag tataccaact tgcttaaaaa agttaataca
    18241 ggaaagattg caaataagta caattattga accagatagt aaagatttaa tatttagaca
    18301 tagattgaat agattaagtg aaggaatact tgatagcata cataaaatag aaaatgattt
    18361 aatgcaagga aaaagagtat taatatgtgt taattcagta gatttatctc aagagttata
    18421 tggaaggctt caaaaatata atcctaaatt aatacatggt cgatttaata ctagagatag
    18481 agagcaggca gaaaaaggga tagaagaaag cttcttattg ataggtactc aaagtataga
    18541 ggtaagttta gatataagtt atgatgttct ttatacagag ttagctcctt tagattcatt
    18601 gttacaaagg tttggtagag taaatagaag gggagataat gctgagttga gcaatattta
    18661 tatatatgat tatgatagaa agcttaatat atatgatgaa gatataataa ataggactga
    18721 tatagtaata tcagatataa tacataatga taattctata gttgatgaga gtaaagttcc
    18781 atcttattta gataatgtct atttagatat agatatggat aaatataata aacataaagt
    18841 tgctttagag attataatga aaaatatgag gttaggggta tggaataaat ctgctaataa
    18901 tgatatgtta aataatgata ctattagtgt tgtgcctgaa tgtcttttag aagagtacaa
    18961 gttgtatatt gataaaaaaa tgtatttaga agcgagttca ttatttgtaa atgtatctgt
    19021 aaaaagatac aattataata aaaagatgtt ttatgaatgt ggagatatag ttgttacaag
    19081 ttatagttat aatgataaac taggtctaat atttgattgt taagagaatt atagtataac
    19141 taattaaaat attttattga gaatttgtta taatttatat cgactacaaa ttttatatgt
    19201 tacaatagaa taattttgca gtgagcgaaa aatatgtgta aatggctgtg agttagtgat
    19261 ggcaaggttt ataactgaat ttttgttttt agctaaaaac actactggtg cctcactgca
    19321 aattaactat tttaataacc ctacaagtgt tgtaattact atagttttat ttggggttta
    19381 aattacacta agttagttat aaatattccg gaaagtactt ttgctatttg attcattcta
    19441 cccgtttaaa ttacactaag ttagttataa atttcactaa ttttagttac aactattaca
    19501 agtccagccg tttaaattac actaagttag ttataaatta tgtgtaatgt attttaatgt
    19561 tttctagcaa caatgtttaa attacactaa attagttata aattttataa attctatgaa
    19621 taattttaaa gagaggtttc gtttaaatta cactaagtta gttataaatt gtacatttga
    19681 catagaagct tcaaaatcca tcccagttta aattacacta agttagttat aaatgtaaca
    19741 gcacgaatga tggcacagac ctatctgcaa tgtttaaatt acactaagtt agttataaat
    19801 agaagtacac ttacaagtaa gataaaagac ccaggtacag tttaaattac actaagttag
    19861 ttataaattc tgtagctata tgtggaagta attttagtag agaggtttaa attacactaa
    19921 gttagttata aattattgaa ggggtgagag ttgtgactag gcactacaag tttagattac
    19981 actaaattag ttgtaaattt acttattcat taagaaactt aactgagagt ttgatttata
    20041 ttattgaatt agcaagagtt ttagaaagta gaaaattata ccccaataat accccaacca
    20101 caaaaataaa taataaaaaa tatccaaaaa aattagtata acatcataac taaatagcta
    20161 tatacctaca cttacgaaaa ccaacaaaac aatcaaataa ccacttgtag actcccctcg
    20221 tctccaccaa ttttgaaaat gaaaataata gaataaaagg aattacttat gtttggacta
    20281 agtaattcct tttattttgc ttaaaagcac acaattagca cacaactaga aggttatata
    20341 aataaaaagg ctgtcgcact agaaaatagt gctacgctct tttttgtata aaaaaataaa
    20401 tcccaagttc aaaagaacct gggattcttg tataataact gtatgctaaa acaaaatact
    20461 acacaaattg attatactac ttatggtgat aattatcaat ttaagctacc actaaatatt
    20521 gattacatga ttccaaaaga tgattctgta aggttattaa gttaaattat tgaggagatg
    20581 aatttagaaa aattatataa gacttattct cgaattagat gaaatagagt aatccataga
    20641 caatttttga aagttataat atatacagat atgaactgta tttattcttc gagagaaata
    20701 gaaagaacat gcaaaagaga tattaatttt atgtaccttc taggcgaaac ctccactcca
    20761 gaccattcaa caattgcaaa atttcgcagt atacattttt aactaatagg caaaagcttg
    20821 attgcacagt ttacaaactt tcttggagat aataatgaaa tttcaaaaga cacaatattt
    20881 attgatggta caaaaataga gtcatctgct aatagatata cttttgtttg gaaaaaagct
    20941 gtaaataaaa atatggctaa aatggtgaat aatatatctg acttcatatt gaaatgtgag
    21001 attgatgttg gcattaaaat agtttatgaa gataaaatta aaatctatca tttaaagaaa
    21061 ctaaaaaaaa tatcaaaaga agcaaatgta gcatttattc atggaaaagg aaatagaaaa
    21121 tctactaaaa accttcatat aatgggtgaa cgaaatagtt gttctaaaac agataacgat
    21181 gaaactttta tgagaatgaa agaagatcat atgaaaaatg ggcaactgaa accagcatat
    21241 aatatacaat ttggtgtaga ttaagaatat atagtttggc taaattcagg aaatcaaact
    21301 gctgatacta caacattaat accattttta aaatctatag aggaatatac taagtttaaa
    21361 tatcctaaag taatagctga tggtggatat gaaagtgaat aaaactatgc atttttagag
    21421 cataataatc agttatcttt cataaaacct gcaaattatg aaattattaa aactagaaaa
    21481 tataaaactt atattggatg tattgacaat atggattatg aagaagaaaa taattattat
    21541 atttgtacaa atgagaaaaa actatttgct aataaaataa taaataggaa atcaaaaaca
    21601 ggatataaaa gtgaaataac atgttacatt tgtgaagagt gtagtaattg tcaatataaa
    21661 agcaattgta ttaagagaag taatagtaag gttcctctta aaaataggac taaaaactta
    21721 caagtatcta agtcgtttca tgaaaaaaga aaagaaaact taaagagaat tatgagcctc
    21781 gagggggatg aacttagagt gaatagaagt atacaagcag aaggagcttt cgctcaagta
    21841 aaataaaata tgaaacttac aagattttta agccaaggta aagaaaatgt tttataagga
    21901 tatattattg tggcgatagc ttataacgtt tctagactac acaataaaat agtaaaaaat
    21961 aaacgtggaa tatatcttta tcatttaaaa aaatattcta aaattattat ttataatcaa
    22021 atattatctg aaaaaatggt atttttatat ctttatttgt catgcataat tttacttaga
    22081 acagaaactt tatataaaac aattgaaaat atacctatta agataattag aaaagagctc
    22141 tcacagaaca aatttaattt gctcatgcaa cagccccata ttgatataca tttaggttgt
    22201 ataattatac atttcaatat tacatgttca ttaggataat agttagtaaa tgatatgatt
    22261 gagagaatag atataataaa ctaatctagt cctgtattgc aatgtttatt aaagaatata
    22321 tttttaaaga tccaagtact gcatctcttc cagaattgag ttggttaata gttttttgat
    22381 gctatgcaat ttataataaa aagtataatg atttagttga tgaatcatca gaatttatac
    22441 cctcaaagat taatcagatt gcaataaaaa taatgatata ttctatagtt ataatatcta
    22501 ttttctttgc aacccctcat acaatgaata taaatatatc aaacttggat atgggtataa
    22561 ttctcatttc agttttattt atacagtttt tatctaaatt aattttgtat gtatattttg
    22621 ataaaaggga gatatgtaac taagtggtaa tattggtgaa aacaaaaatt aaagaatata
    22681 gaaaaaaact ccttatgaca caaaatgaac ttgctaaatc agttagggta aggtgtgaga
    22741 ctattgtaca cttggaaaat ataatccttc tttaaagtta gtgatagata ttgctaaagt
    22801 attcaatact acagtagaaa atttgtctga atttattgaa gaaggatagt ggatagatta
    22861 taaatagtta taagatggtt aatgaaatat agttacttaa ttattaagtg tgttagaaat
    22921 atttatatgt aacacaatgt gtagttaaga ttaccttatc tcatctaaga ctttaatttt
    22981 tcttcccata aagagggtat atcaattttc tagtgtggta gcccattttt tattgattta
    23041 aatttataat atatattaat agatgatact taaaaatttt ataaaatatc taagttgtca
    23101 taaataaaac gatatatcta accgaatatg gtaaaatttg ttataatata gataagttag
    23161 agtaaaaata attttaatgg gggagaaaat gcagtcagta atatgtaaaa tttttgataa
    23221 taaattacta attagtaatg atttaagtga gcaggatgat gtattatatg aggtaatgga
    23281 taaatttata gatgatattg aatatatttc aaaattagga gatgagcaaa ttaaaagtat
    23341 gcttatggag gtaaataaat ttgaagaaga ttcaactgaa tttgaactat atatgaaaaa
    23401 cttatgctat ttaaagcaat catattttat agatactaat gataaaagtg aaataaattc
    23461 tatagatata gatatattaa aaaatgttaa aatagaggac ttagttgata taactaatat
    23521 taaattagaa cgaaatttaa atataaatat agaacatata tctaaagctg taaataaaat
    23581 atatgaagaa aatgaaaagt ggaaagagta taatatacaa aatactatgt ctaaatatat
    23641 aggtatacct gaatcagaag ttatatttat atcaaatttg agtcagtatg tttcattttt
    23701 atctgaacta gataacgcag gcgactatgt atctagaggg caaaaagatt gtatgtatga
    23761 attattacca tcattacata gaaaatataa aaaagactat ggtatacatt cagatgaata
    23821 cgaggaagca ttcaaacaaa aaataattta ttatgataaa gaaataaaaa atagatcgag
    23881 tgaagaatta agagctgaag ggcaacattt tggactacca acagaatatt tagatttcac
    23941 agaagctcat ttaatatcat tattatttgc aatagaagac tataaatata caaaacagca
    24001 ttcaattgtg tactttatag actctatttc ttataatact gacactataa aaagatctga
    24061 gaagttagta aattattcag atacatctgc aatagataat tgtagtaaat tttcatcaag
    24121 atcatttttt ataaaggtag ggaattcaaa tgaaagaata cattttcaaa aaggatgttt
    24181 cctaaaagta tcatcagaag ataaaggcga atttaaggaa aaattaaaaa agtattgtaa
    24241 agtagtagtt attaataaag atgctaaaaa agaaatatta aaagaattat ttaatttagg
    24301 tattacattt gaaaatattt atccagataa agataatgta gttaaatcta taaaattcta
    24361 ttatgatgag atagtagggg gaaatttata atgagagaac aatttaaaaa ttctataaaa
    24421 aatattaaat caaacagacc tcttgtatca gtccaagata ttgtgaattt tattgataaa
    24481 ggagaaaagt acttgaaatt atcaatagat gaaatagatg aaatggaaat tttacaagga
    24541 atagttatga gtcctgatta tcaacgtaca tataaatcat caaacaagga agaaagttct
    24601 ataattgaat ctcttttaat tggaatacca atacctgaaa tatttcttgt aaaaataggt
    24661 gtaaatgata tgcaaataag acatgtaatg gatgggcagc atcgtttgaa tgctatatat
    24721 aggtatgtta agaataaata tccacttaaa aatttagata tattaggcaa tgacccacta
    24781 tatgataata aaaggttttc agaattagag aaaaaagata aaattaaaat attaggaagt
    24841 catttatcaa ttctagaatt tgatggtttt gataatccag aaatagaaat agaattattt
    24901 aaaagatata acagaaatac aaaaccatta gagatgcaag aaatcgagat ggcaacatat
    24961 ttttcagaaa ctagtaagta tataagtaaa tttataaata ctctaataaa agataaatat
    25021 aaggatgaaa tagataaatc agaatataaa tatgctaatt acaaatcaga tttacttaga
    25081 atatataaca taactaaatc tcgtaatgat aaacaaaaaa atcatcaaga aatatgtata
    25141 atatttagta ttttagaaaa tgggctacaa gaaaatatca gagatggagt tacagcctct
    25201 aagaaatttt tagagtataa gtcaattcag tataaaaata atgaaagtga aaaattagag
    25261 ttattaaaag ataagtttga tgagtttaat aggatgatac tgaaaatatc tgagaagata
    25321 gaatatccat tctcaacaag tttaatatct gatgataagc aaagacaaag taaatacttg
    25381 ataggagtat ctattgtgtt ggcttctatt tgttattatt atgatataga cttggaaaat
    25441 aattatttaa tacaagatat taaaaaaata atatcttgtt cacccatagc agatatagaa
    25501 tataaggcgt cttcaactaa tatgaaaaat atgattctat acttatttat aaagaataaa
    25561 atacaagata ataaatttga atcattaaat ttaaaaagag ataaaattaa agaaataaat
    25621 actttagtaa tgaataatga tggttattta aatgaacaga caaggctatt agaaatatat
    25681 taacaagtta taaaataaat catggtaatg taaaataatt tgtgctttta aggttaataa
    25741 aaatcttctt tatggcaatt atttaaatat aatcaaatgt cgtaaaggag attttttatg
    25801 aacgctttaa gaaaacaatt agccaaagaa attatatcag atatctaaaa aagagcatgt
    25861 caaataaaac cctaggtatt taaatttttt tagagctact taaaataaat tatgctatct
    25921 ctgtatttaa atatttccta aattcaagtg gagacataga atttaatctc ttttgatatc
    25981 taaaattatt atagtaatat atataatcct ctattgtttt gactaattgt tcgtatgtat
    26041 caagttttct taaatagtac atttccactt ttaaaattct ccaaaatcct tccataggag
    26101 cattatcaat acaacgagca actcttacat actttgtatc atgccttgtg ttaaaagttt
    26161 tgatttaaat accttactag tatactggaa acttttatca ttatgaaaaa taggttttgc
    26221 atttggatat agctctattg ctttatcaaa agtttctaac accaagttat tgttatttga
    26281 ctttccaata acatatgaaa ctatacttct atcgtctaaa tctagaattg cgcttaaata
    26341 ggccttcatc ccattggtta atttaaattc agttacacct gttaaccatt tttgagaggt
    26401 tttatctgca ctaaattttc tacttaatac attttccgcg atcacttctg gcgtacattt
    26461 aacataacta aatttctttt ttctgcaaac agaacttaag cctacggctc tcattagtct
    26521 gtacactctc tacaatcttt aacaatttca actctttcat ctaatgctgt ttttctagtc
    26581 tccataaaga tttctccctt cgaggtttct tttatctact tatgaggatt atactcttta
    26641 ccccaagctt ttagtgaata aactgatctc attttatatt tttttgagat tgtgtcataa
    26701 gatccttcac catttagata agattttata gcattcaatt taaattcttc acaatagcat
    26761 aatttacaac tttgttttat taaaccatca tttccaaaag cttcataatt tcgcatccac
    26821 tctctgaatg tacgtttatc caatatttaa ttcttccatt atttttatta ctgtattctc
    26881 accttttaaa tatgattcaa ttgcttcgat ttttttgctc tgaagatatc ttagttttag
    26941 atagtcttac atattttaac tgtctcctaa gatgagtata attcattcat catcagttct
    27001 atagaataca cctagttcct acttactgta ggaactagga ctatatgaaa cccattcata
    27061 gattgtagtt tcttctgttg cattatagcg cagaatagta aattcatgtg aaattttatt
    27121 ttgaatttac tatttatata taaatgaaga gtggtcttat tttcaattaa aatttggaac
    27181 aattttgggt tgacatctac aattaaggat ttaagttttt gttatactaa taaataaaaa
    27241 cagagattca aaatatataa ataatactta aactagtgct gatagatttt ctttaagttc
    27301 tagttttttt attgtcatta tctaatatgt actattttat gtacagtcaa tataatctga
    27361 aattgtaaaa tggtgtataa tatagttata agtaaagaag ggatttaaac atgtatgatt
    27421 acaaaaataa aaaagactta tatatacctt aaggaaatac aaaaaatata caaaatcaat
    27481 gagcataaag aactagtaca cataataaaa aaactaataa atgataataa aataaaacca
    27541 ataaaaacct cagatctaac acctcagcat gagcaattat atacaaagta tagaataata
    27601 aaacaagaaa cagaagaaga taaaaaaata ttagaagaaa taaattacaa aatatgtgat
    27661 aaattaagta tagattatta tagaaaaaac ttagtacact ataaaaataa tagagttgca
    27721 ataatggatt taaatagtta tcttattaaa aaatctgata atctatcaaa gaaaatatcg
    27781 attaacgaaa gatcttatga aatatttaag gatgagaaat tcataagtag taaagtagga
    27841 aaagaagtac taaaaaactt aaaaatagat ctaataaagg atttaaacgt atataagaca
    27901 ccagagccat tcatatattt atcaataaat cgtatatctc cacaaaaaat attaattata
    27961 gaaaataaag acacttacat aacaataaca aaaatgctat tagaaggaaa agaaatactt
    28021 aaaaataaaa tagatactgt tatatacgga gaaggaaaaa aaataatcaa cagtattaaa
    28081 ggattaaagg aagatataac aattgaatat cttacaaata aagaaaatga atttttatat
    28141 tggggagata tagataaaac tggattatca atatacactt ccctaaaaga taccaatgaa
    28201 attaataata taagattatt tgaagttgct tatgagcata tgatagataa aacaaaggaa
    28261 aataccttga ggaatatccc caaaaatcaa aaagataatt ttgaatgtgg attagaaaat
    28321 attaataacc taaacttaaa agaaagtatt aaaaatattt tagtacaagg aaaatacata
    28381 cctcaagaag ctctaaatag attcgacttg gaggaatata actaatggaa atgattaata
    28441 ttttagaagg ctacaataag agagtaaact gtataggatc ttattatctt attgcaactc
    28501 ttgctaacaa tagaaataaa tttaaagaat ttgacaacat tcaattttac aatttattaa
    28561 ttcaagtttt gtgttatata tttgatagat ctcttagaag aaagaactgt ttaagagatg
    28621 atattaagga ttttattgaa gaaataaatc gtatggatta taaaataatg ctttcagagg
    28681 atgacttaaa ggatttagca aactatataa ttaatggatt aaccaatagt ggtaaagtat
    28741 atctatttac ctactattct ttagaacaag aaaaacatat agatgaaagt attaaaatta
    28801 tagaagataa aaatgtaaaa ataaataatc aggaaagact atcctactcc ttaacaacag
    28861 agggttatag attgttgtta tcaacaaaag aatatgatga actattccaa attcaaatat
    28921 cacaaatgat tgcaaagtta aggatagaaa agggtgatta tcaaggcgca aaggaagata
    28981 tttacgatat aataaatacc ttagagattc atcaacagaa aattgataat tatataaaaa
    29041 taataaaagt aaatatacta tatataaaag aagaaaaata ttcaacagta atagatacaa
    29101 ctgtagaaac acttttagaa gaaatggaca aatatgaaga attaaaaaaa gaagtaaaac
    29161 tattaatcaa agataaagag gactacttgg aaaaggatga ggatatagac aaagaaaaga
    29221 taaaaaatat aagaactcaa ctattacaaa tgaaagaatt aatagatgga atagttttag
    29281 caaagtctac agccacaaat ttgttatcta gagttcaaga ttttagagaa gaatttaaag
    29341 aaatacttaa aaaactatta acaactccag taattaaaag attcaatttc aaggaagaaa
    29401 tcttagatag acttgaaaaa gacagtgatt ttttattgat aataagagaa ttatatatat
    29461 ctttatttaa agtagagttg ccaaatcgat ttaatattgg agtggcatat caagaacaga
    29521 aactattaaa tactagagaa attgaaaatg aaatagttaa taaagacgag ttagaaatta
    29581 ttgaaaataa agagaaggag gaacgtataa attattgtga aaattactat tttgattttt
    29641 ttaaatactt aattaaatat ggacttgaaa aaggacaatt tacattagaa gaatttctaa
    29701 aaaattatct gaaatatgac aaagttattt acttagaaat aactaaagac tccaaattga
    29761 tgagagatat aataatttac ttcgctaatc aaagggaaag tatcaatatc aaaaagataa
    29821 tcagaatgtt agaaaatagt gccttctcac caaatacaga ttttcaaatt gaaagattaa
    29881 tagaacgttt attagtagaa gattttgaac tattaaatag cgttagccat attaaaagta
    29941 ataaaatatt tgaagatgaa atgaaaataa atactgaaat aaatttagaa actatgactg
    30001 cagttaagct agaaatagca aatataaaat ttgaaataat ctaaatataa ggggaaatac
    30061 aatgaatata tctttaaatg actataaaat agccaatgaa atattttata gattacttaa
    30121 aaaaagtgag ttaaaagaaa aagaagctaa agaattattt ttagcttata taaataacag
    30181 taatgtaagg tatgctttag aggcaatttg tgaagtatct aaaataaaaa taatattaat
    30241 ttcagatacc ttatacttaa taccaaataa tgacaatgat atttttgggt ttgactatag
    30301 aagagaatct ttattaggga aagatttaaa agatagttat ttaggatatt tgataatgac
    30361 aataatattt tctgaattta caaatggggt agcaccagca tcatatattc aagtattaaa
    30421 cttactggat ttagtacaag aatccttaga acgttcaata gctcgtgata atctagaaga
    30481 aatagaaaaa tcatgtgagt ttaatataac tatcttaaag aactattggg aaagtaaaag
    30541 aaagtgggac gaatctagta agaaaggaat agaaacaaca tcagcagatt tccaaatagg
    30601 gtttattaga aaaataatta atttcttaaa aaatgaaggc ttaattgtac acattgagga
    30661 tgaagataag ataaaaccaa ctagaagatt tcttgatctt atgaataatt attttttaga
    30721 tgaagaaagg aaagtattaa tagaaaaact agttttaaga aaaggggaaa gtattaatgc
    30781 cagtaattaa taaatacaaa attataaatt ttaaatttgg tatgggacaa gaaagaatac
    30841 ttagcaacag aaccatggaa ctgtatggag aaaacttaca agtagaagca gaaaatacag
    30901 caggcaaaac tatgagtatt caaactatca tacaaagtat ttgtccacta tcggatgtag
    30961 ccaaaccgtt tactgcaata tataataaaa aagaaccatt atactcaatg actgaatggt
    31021 tgctagatga tggtaaaacg ttattattaa cgggaatagg atttgagaaa aaggctggat
    31081 catctaaaga agaagggaaa gaaaaaaagg acgatttata caaatacttt atgtttatta
    31141 tagaagaatc taaagaaatg gaggttgata tagataatat acctttatta aaaaacaatg
    31201 acaaaggtat aaggatagta caacctttaa cggcctcaca agactatata aaaatgctaa
    31261 gagataaata tggaaaaaac aaagtacact tctttaataa ttacttaaga aaacaacata
    31321 gagaaaaatt agaagaatat ggaattaacc aaagtgaatg gaaagaaatt attataaaac
    31381 ttaatagtaa taacaaagaa ggtggactat cagactttgt taaagaacat aatacttcag
    31441 aaaaacttat aagagataaa atattacctt taatagagac aagcttaaca acagaagaat
    31501 tcgctccaat attgcaaatt aaggaacaag taagaaagtg tataaataat attatagaca
    31561 tgaatgaaaa attatcagat tataaaaact atagagattt aaacattaga gttgaaagtt
    31621 tacaaaataa aataaatagg atcctattca tagaagaaga taaaaataat gtattaggag
    31681 aattagctaa tctatatgta catatagaaa ataaacgcaa tgaattaaat gaagaaataa
    31741 aacagtatca aaaaatgaaa gcatcaaaag aagaggaatt taagatagta gaatatgaag
    31801 aagatagcta tgagtatttt agaaaagaaa aagagataca agatactcag gtagaatttg
    31861 ataaagccaa aaatgaatta aatgataaaa tagaagaact agaattagat gaacaatatt
    31921 taaatatatc aaagttcaaa agaaaaaaga aggggctaga agaaggggaa aaagataaga
    31981 tagaaaaaga aagtgaaaaa caaagaaaag aggtaaatca agaagaaata acggctatta
    32041 taaatcgtct aggtagcagt attcattatt gtttaaagga agaaagtatt ataaataatg
    32101 aaaaacttaa agaaaataca aacaacaata tagctataca agaaaaaaag aatcaactta
    32161 atgatgacaa aagtaagctc acaaaagtat tgataagtaa aaattcagaa attaaatata
    32221 tagaaggcaa agaacgtgat tttaataatc aactacatga atttaaactt aataacactg
    32281 atattaaagg ctttatttct aataattttt taggcgaagt aatagattat actaggtata
    32341 taaattattt aaatataaaa gtaaaatcaa tagaagaaaa tcttgaatcg aaagtcatgc
    32401 aaatagaaga atcgaataaa cttaaggatg atataaatga agctataaat aatcttaaat
    32461 tagataatca tgaatcttat atgaaactgc aagtattaaa aactagaaag aaagatatag
    32521 ataattttaa agaaaaatat aaaatcatta aaacaagatt tgaaatagac aatgaattag
    32581 ataactctac taaactatat aaagaggtaa aacaagagct taacaaaatg aaacttcaag
    32641 tacaggactt agaaaataat aaaaagcaat tagaaaaaga gctagaagat ttacaaaatt
    32701 ataaagatat aattttcgaa gaagaaatat taacagatct agaaagaaat ggaataaaac
    32761 ctattgaagg catgaaatat ctattaacct tagatggaga tttagaatac aaaaataatc
    32821 tcatatctaa aaatccattg ctaccatatt ctataataat tacaaataaa gagtatcaaa
    32881 aactgaagca aataaactta aaaaataaaa ctaaaatctc aatgcctata tttgtaagag
    32941 ataacataga agatactttt ataactacat ctagtaacct tgtaattagt aatggattaa
    33001 atatactatc ttctttcgat aacaaagctt tagatcctga aaaaagagaa aaggatatga
    33061 atctaatcaa agaacaaata aatagtattc gagataaagt ggagcaatat aaagcagaaa
    33121 ttgaaatatt agaagaattt aaacttctaa ctaataaaat tgattttaca gctgaagact
    33181 tatccataga tgtgaaaatt gaaaattata aaaaaattat atttgaaata aacaataaaa
    33241 ttaagagtaa tgaaaataat gagaagaatt tatctaataa aattaaagaa ctttacgaaa
    33301 ataaagaaaa gctattaaat aacaagaata tattatttaa taaattgaag gacattagaa
    33361 atatacaaga tacatattct ataattttag aaaataaaaa tgaaataact aagttaaaaa
    33421 caagtattga aaaaatcgaa gaagaaaaaa aagttattaa aaaatcaata gaagatattg
    33481 atgttaatat atttaattta aattcagaaa aagataggat aaataggcat atagatgata
    33541 cagaaagcaa gataaataaa tttaagattt atgaacctat taaacttgaa aatgctaaac
    33601 tagaagaatt agaaataaaa tacaagaaat acttagaaga ccctacaaaa aaagagattg
    33661 aaacattaaa ttatgaaatc tcagtttgct taaaaagaat agagagtatt actatagagt
    33721 tagaagaatt tagacaactt attagtagtg ataattttga aaatatacct atattattca
    33781 caatagaaga acttaataaa agaatagttt taaataaaag taaggttgat gaactacgaa
    33841 aacttaaata tagtattaaa agcgacatag ataaaaatca aggttcatta aacactaaga
    33901 gggaggagat acttaaaaaa tttaatggaa aagaaccttt atctactagc ttaatagtga
    33961 actttaattt tgaagaaaga aaaatagata taaaaaaaga tataaaggat attggtgaaa
    34021 ttatagaagg taatagaact acttgtcaaa atctagaaca ggaattaaga gacttaaaga
    34081 aatataaagt agaaagaaaa gctataacct atcaacctga agatattttt attgaaagta
    34141 aaaaactaca atcaaaactg caaaatgttg aatataattt aattaaatct ataaatagct
    34201 ataaaaatac aatattagaa ataaaagaat ttaattataa gcacatggaa aaatacaaaa
    34261 actttataga aactttaaat gtaaataaag ataattactc tcgacaaaaa gaacaagtag
    34321 aaatagtatt actagttata agagaagaaa taagcaaatt agaaaaacat agcgaacaac
    34381 taagaaaaga aaagactata atatcaaggc aaataaaaga ttatgttatg gactgtattg
    34441 atgaatttaa aatcataaat aaacttggta aacataaagg acaagcctta ttcaacatat
    34501 cactacctaa atctgataaa atagaaaata gtttgagctt agtagatatg ctaatggatg
    34561 aaattgtaga agaagcaaac ctaggtgatg ttgaacaaaa aataaatacc ttttatattt
    34621 taaataagac tcttaatata gggagaattc ctgtatcagt tataaaatat gaaataaata
    34681 gaaatgaaac tataaagtgg aactctatta ataacgaaac aacaggagga cagagatttt
    34741 gtatctcatt tattgtgaca atattgttga tggaatataa aagatatgat agaaatgcaa
    34801 tagttgatga aagtaaatat aagggtaagg tactacttat ggataatcct tttggagaaa
    34861 cgtcgcagca agatttcctt aaagaaatat ttgaacttgc taaaaaattc aacgttcaaa
    34921 ttatatccta tactcatgta acaaatgctt ctataagagc aatgtttaat aagatttatt
    34981 taatgacagt tgaaaaaact acttctaata aagaatttgt ggatattaat gagattaagc
    35041 aaaataaaac tgatgaattg gtgtatatga gtaaatttta tataggtaat aaagaagaat
    35101 taattcaaga ggatatattt agtttaatat aaataacaag taaacaaata aagtgattac
    35161 tatcagtgag gcaggtagaa actgaattac tttgtgactc attacgactc ttggggtaaa
    35221 attgtgtata aatgtgaaga atttcgtgat tgtcagtaca aaagcagctt tattaagggt
    35281 aataatagta agactcctct tgaaaatagg actaaaaact tacaagtatc taagttattt
    35341 catgaaaaaa gaaaaattaa agagaattat aagaccagag ggatgtgaac ttagagtgaa
    35401 tagaagtata caagtagaaa gagctatcgc agaacaaatt taattttatc atacgatagc
    35461 ctcttgttat tttagtgatg aaatccatca agcataccat aactacagaa aaagaggctt
    35521 ttctgatggt atattgggtt cttttagagt gtgtgatttg ctacatgttc attaggataa
    35581 taatagtcag taaatgatat tactgataga atagatataa taaactaatc tagttccata
    35641 ttgtaatgtt tattaaagag tatactttta tgattataat agctattttc tttgaagctt
    35701 attgtacaag agatttgaat atatcaaatt tggatatagg tataattctc ttagcagttt
    35761 tatttataca gtctttatct aaattagtgt tgtatatact ttgataaaag ggggatatgt
    35821 aactaagttg taatattgat gaaaataaaa attaaaaaat atagagaaaa actccttatg
    35881 atacaaaatg aacttgctaa atcagttggg gtaagacgag agactattgt acacttagaa
    35941 aatggattaa tgtaccataa aggtatccaa gataaatagt taaaaaacta gataagaata
    36001 aggagccttt acagaacaaa tttagtgtgc tcgtgcgata gccctttttt tataaaaatt
    36061 aatctaataa cctatataat taaatttata aaacatatat gaaagggtaa aactatatgg
    36121 ctaaaattga taatatgatg tccatattat ggatgttaaa ctcagacaaa aaagttaccg
    36181 caaaacaaat atctgaaaaa ctagaaataa atataagaac tgtctacaga cacattgatg
    36241 cattatctgc tagtggagta cctataattt cagatacagg tcataatggt ggatatacac
    36301 ttttgaataa tttcatcaaa gcacctcttt ttttcgatac agaagaacaa actgcgttac
    36361 ttcatgcagc tatatttgct aaagaagagg gaagtttctt agatgacaca ctagacaaag
    36421 caacctcaaa gttaaaaatg tattcaaatc aaaaacaaga agaaacttta acaaaacatt
    36481 taataggttt tgaagtaata aaaccaactg gaaaaatatc catagaatct gtacttaaaa
    36541 agttaaaaaa tagtatagca aatgaattat ctgtagaaat caactatcgt acagctcatg
    36601 aagaaaaatc aaaatgtagg attataaatc catatggaat tgtacgttgg aataataatt
    36661 ggtacatagt agcattttgt caaatgagaa atgagattcg tagttttagg gtagatagaa
    36721 ttagtagtgt catagaaaca tcaaatactt ttaataggcc aaaagaattt tcagcaagtg
    36781 aattttttat aagagggatt atggatgaaa caaaagatga ggataatctt atatcattag
    36841 ttatagaagg aaagatgaat gcattggata acttatgtca gcattggctt ctaggatatt
    36901 atttaaaaga aaggacttca aataaagcaa tatttaaact tcaagaagag ataatattta
    36961 catatgtacc gaatatactt ataccttata gaaaatctat acaaataatt gaaccattaa
    37021 gccttaggga taaaatggtt gaagatttac tcgaattaat taatcattat caaatttaat
    37081 aacttaactg acagagtatg tcagttaagt tattttacaa ttaggtatat taattaatta
    37141 tagaaggagc aaaaaaatga aaaagagaaa agtatatatg tatgtattcg atactatgtc
    37201 agattgggaa gttggatatc taactgctga attaaataca ggaagatatt ttaaaaaagg
    37261 attaaaacca ctaaaagtaa ttacagtagg agttgataaa aatcctatta taacaatggg
    37321 tggattaaaa gttttacctg agattacaat tgacgagctt aatattgaaa gtaatgactt
    37381 attaattttg ccagggggaa atacttggac atctataggt catgagaaaa tattagaaaa
    37441 atctaaagag gctttggaac aaaggtctat agttgcagct atttgtggtg ctactttagg
    37501 gttagctaaa acaggtttac tagattttag aaatcataca agtaatgatt tagaattttt
    37561 aaaaatggtg atactaagtt attctggaga aaaatattat aaaatggaat ctgcggttaa
    37621 tgatgaaaat ttaattactg cttctggaat tgcaccatta gaatttacag tacaagtttt
    37681 aaaagtttta gatgttttta aagaagaagc attaagttct tggttgaacc tttataagac
    37741 gcatgactct aaatattttt tcgaactaat gaattgtaat aaataaattt aagatttaat
    37801 tttaaattca aattttaaat tactttttct atggcaatag ataagtagtt tagaatttta
    37861 tcatatatat aatttgtatt tataccaaca caaatagaaa tgatagttcc aataataaaa
    37921 tttataatta gttccatatg gagtacattt ctttcctact aatataacta agaatatatg
    37981 aaaccaccat agattgtagt tttttctgtt gtattatatc atgggatagt aaagtgacgt
    38041 atatttttga tgaaaaccta ggattgtata tgaaatgaat taatcctgtg tattaatctt
    38101 gagattcgtg tctaatgatt tgtaaaaata aataatgaaa tacttagaaa tacttgtaaa
    38161 tgctagtcaa tattggctag tattttttat tttagtaatg aaatccccaa ctgtacttca
    38221 tccacaaaaa aagagatatt tttgagggtg tattggagtg aacttaggct gtataattat
    38281 acatttcaat atcttatatt aattaggata atagttggta aatgatatga ttgaaacaat
    38341 agatataata aactaatcta gtactgtact gcttactaaa gaatatattt ttatggtata
    38401 agaatttttt agagcgttga ttctatagga gtgaataaaa aagtaatttt ataatattat
    38461 ttgtaaccat tagatgtcta ttatgaaatc ttttatggac tatatttgta aaaatattat
    38521 taagtattta caatattttc ttgcaattta tttggaaagg ttatatattt ataacatgaa
    38581 gtgttataaa tatataacct ttaaggtgga ttttatatgt ctaaatcaga aactggtgta
    38641 aaatcaaaac tcatattgga attacttgta ataacttatc tttttatagc tgtattagct
    38701 actaagtata tttttaaagg tccaagtact gcatctcttc caggactgag ctggttaata
    38761 gtctttggat gctattcaat ttataataaa aaatataatg atttagttga tgaatcatct
    38821 aaatttatac tatcaaaggt taatcagatt gcaataacaa taatgatgta ttctatagtt
    38881 ataatagcta ttttctttgc aacaccttat ataagtaata taaatatatc aaacttggat
    38941 actggtataa ttcttattgc agttttattt atacaatcgt tatctaaatt aattttgtat
    39001 atatactttg ataaaagggg gatatgtaac taagtggcaa tatcgatgaa aacaaaaatt
    39061 aaagaatata gagaaaaact ccttatgaca caaaacgaac ttgctaaatc agttggggta
    39121 agacgtgaga ctattgtaca cttagaaaat ggaaaatata atccttcttt aaagttagcg
    39181 atggatattg ctaaagtatt cgggaccaca gtagaaaatt tgtttgaatt tattgaagaa
    39241 gattagtaga taggatataa atatttataa gattgttaat aaaatatagt tatttaatta
    39301 ttaattttgt taaaaatatt tataaataat ataatgtatg agtaaagtta ggttgtaatt
    39361 attttaagat aagaagacta ctgtaaatga taaaaattag tgaatataca gccaattaat
    39421 aaataataga taaaacttta aagcttagat gtgaggatga gatatggtct tacagtagtt
    39481 cacactttta attaagactt aaaatggaaa ccatacacat acatacacta tttactgaaa
    39541 gtggactaga taaaaaaata ataagtgatt taagaaagta tctcatatac tatataagta
    39601 ttattttagg tgacctattt ataggtcatt ttttatgtat ataaatgata ataatactaa
    39661 tatttaaaat aggttttaaa gaaataaaat atccagattg aaaaatggat taatgttaat
    39721 aaaaaaatta tatgtataaa aataggtata attatagaaa aaaacaataa taaaataagc
    39781 tgttatagaa aaatacaatt atatagattg ttgttgaatc attgactgca agaataataa
    39841 catttaaaat gaacatggag aatatggggg aggaatcaat atgaagagaa aaatagcagt
    39901 tgttttatta actgtagcaa tgttattatc acttgtagct tgtagcaatg ataacacatc
    39961 aaaaagtgat aaattagagg atacattagt agtatatact acacatggag aggatatgct
    40021 aggagcaatt tctgaagaat ttacaaagga aacaggagtt aatgttgaat ttataaactt
    40081 aaaaggtgaa ctagcagacc gtgttagaag tgaaaaagat aatccgcaag cagatataat
    40141 gtttggtgga gatacatcta catacatgca attaaaagaa gaaggattat atgaaaagac
    40201 tgaaccaagc tggaataatg aattagacaa gtcttacaaa gattcagatg gatattggta
    40261 tggaactata aaaacaccag taatgatgtt ttataacaca aaactattat cagctgataa
    40321 agcgccaaaa gattggagtg atttaacaaa agaagaatac aaagacttaa tagttactag
    40381 agattcatta tcatcatcta tgcgttctac tattagtaac ttaatcaatt actactcaaa
    40441 tactaagagt gaagaagaag cttggaagta tcttgaggat ttaaataaga atataaagaa
    40501 ttactacaat agtggaagtg tcatgtattc agcaataggt aaaggtgaag ctacaatatc
    40561 tgttgcagta ttaagtgata taatagagaa taaagaaaaa aataatatgc cattagaagt
    40621 tgtagatgca gagagcggtt ctgtagtaat cacagactgt gtagcagctc taaaaaatgc
    40681 accacatcca aatgcagcag ctaaatttgt agattttgtt ggaagtgcta aggttcaagc
    40741 tatggttgca aatgatttta atcgtattcc aacattagat tctgcactta aagattcacc
    40801 aaagtggatg tcaaaagaat ataaagctat ggatgtagat tggtctgtaa ttggaaaaaa
    40861 tcagtctaac tggattgaaa agtgggaaac agatataata gataacaata aaactataaa
    40921 atagcctaat taaataattt aatattatat acaaaaatag tgaggatttt cctcgctatt
    40981 ttacgtataa ggaaactata gtatctcata attttgtata attcatacaa caaaatgata
    41041 ctaatacata cttattaaat aaaatagttt ttgagtaact gatgaagtaa ttgactatat
    41101 aaagtgattt gtagacatag tctctcaaat aaagtgaatt ttttattatg caaaactttt
    41161 aattatagta aaagtacaat ttatatgggc aaggagataa aaatggaact aaaaattagt
    41221 gattataaat tattatgtaa taaaggtagt ggcgctttta acgaagatat cgtaggttta
    41281 tcaccttatg gggcatgggt acttgatgga gctacaggtt taaataataa aaatttagtc
    41341 tctacagaaa gtgatgccaa atggtatgta agttggtgga atagttatct tcatgagaat
    41401 atggaaagag aagatagctt aaaagtaatt attaaagaag gcattgagga gataacaaaa
    41461 gagtactaca aattaacaga tgataaagaa gtagaagcaa tagatattcc ttcttgttca
    41521 tgttctatat taaagtttta taaagataag atagagtatt tacttttagg agattgtact
    41581 ttattagtta acaataatga atctgtgaaa attttaaaag atgagacttt atgtgaactt
    41641 gataaaaaag tatttgattt tatgaaagaa gccaaagatg ctacaaacct tactttaaag
    41701 gagagaaaag ccgaggtaat gcgattataa tagagaatag acttaagaaa aatactgtgg
    41761 ggggatattg gactttggaa ttttctaaag aggccgttga caattgtgta agtggattta
    41821 ttgatataga atataaaatg aaaattatga tggctagtga tggtttttca tgtggatatg
    41881 atagatataa gatttttgat aaaaatgaaa tgatgaaaat agcagagatt aaaggtatag
    41941 attatatata tagaaaggtt agggaactag aaaaggatga tgaaatggca atagagtttc
    42001 ctagatttaa aatctatgat gattcatcat gtgtatattt agagatttat aaatattaga
    42061 taatttatgg agacgatatg aagaatatag aattaaaaga aattaatcat tattatggaa
    42121 aagaaaaagt attacatgat attaatatat ctattaagga aggagagttt tttactttac
    42181 taggtccttc tggatgtgga aaaacgacta ttttaagaat aattggtgga tttataaaac
    42241 cttcttctgg aagtatttat gttggtgata aaaacattac caatttagaa ccagaaaata
    42301 gaaatatggg aactgttttt caaaactatg cactgtttcc aaatatgaca gttgaagaaa
    42361 atgtatctta tggattgaaa ataaaaaagc tgtctaaaaa aattataaag gaaaaatgtg
    42421 ataattattt agagctgtca ggaatgaaag attttaggaa aaaaaagatt gatgaattat
    42481 ctggtggaca gcaacaaagg gtggcagtag caaggtcatt agcgactgag cctactatgc
    42541 ttttattaga tgagccaatg tctaatctag atatagcttt aagaatcaag atgagagaag
    42601 aaataagaga gatacagcaa aagacaggta ttactacttt atttattacc catgatcaac
    42661 aagaagcctt agctatttct gatagaatcg ctgtaatgga taagggtaaa gttcttcaaa
    42721 ttggtgtgcc aatagaagtt tacaaaagcc cattgaatga ttttgtagca aactttgtag
    42781 gtacttcaaa ctgtattgga aaagaagatt atgttaattt taatattgaa aaagagacaa
    42841 agccttatat ttataaaaga cctgaagaaa tgatattatt gcaaaataca aatcaaagtg
    42901 gttttgtaaa agtaaaagta gaatctaaga attttctagg agcaatttta gaatatacag
    42961 tatcaaatga tgggaaaaaa tatcaagtaa ctgagcttaa tagactgaat aatagcaata
    43021 aattaaacgt aggggatatg gcatatttag gtgtgctaca aggtgactaa tatgattaaa
    43081 aaaataaacc gtagtaaatt tacatctaaa aatgttattt ttattgtttt atacagtata
    43141 ttattttgga ttttgattgg atatattatc ataccaatag gcaatacttt tgtacaagca
    43201 ttccaaggta aaggtggata ttcttttgaa gtttttaaag aatatttttc aaatactaat
    43261 aatttaaggg tagtaagcaa tactataatt ttgggattgg gttctgtgtt cgtatgtgga
    43321 attatgggaa tatcacttgc cttatatatg acatttgttt gtgataaaca taagaaaatc
    43381 atacatattc ttttactaag tccaatgatg attcctggag taattatggt aattgcatgt
    43441 attcagattt atggagaaag tggaatagtt acaaaatcta tagaaatttt actccccttt
    43501 atcaaaaaac cttatgattt tagtggatta aagggaattt tatttgtggt tgcttatact
    43561 cagtatgtat atttttattt aaatgtatat gttgccttaa aatatgtgga ttactcaaca
    43621 gttgaagctg caaaaggaat gggagcatca aagctaagag tattttttga tgtaatatgg
    43681 cctgttatta cacctgctgt tataacttct actattataa cttttgcatc agggattagt
    43741 tctttctcag ctccaaatct tataggtggt ggttttaaag ttttaagcac tcaaattgtt
    43801 aggtctaagg ctaataacca tatggatata gcttcagttc aagtaattac tttattacta
    43861 atggggattt tatttatgat tttattacag tattatggca aaaaatatgg agtagtgcca
    43921 tccttaaaat ctcaaagtta taaagttcat aatagaaaaa aagacttatt tacatttgta
    43981 tgtaaggtta ttattgaaat acaaattatt atgattatgc ttcctatagt tactattgtg
    44041 tatttatcct ttgtaagcac acattcaatt atgacaacca tatttcctag agactttaca
    44101 ctggaaaact atcagatgat tttccaaaaa tcacgtgtat tacagcctat attaaatagt
    44161 ttcaaaatgt ctttaatggc agtagcagta ggattgataa ttactgtacc agtatcatat
    44221 ttagtaatta aaaaggatac tgcatataat cgactagcaa aatttattat aatgttacct
    44281 tggagtatgc ctgcaagcgc cattgcagtt aacctaatta atacatttaa tcaaaaaagt
    44341 atatttgctt ttaatgaatc cttaatagga ggtttttata ttgtacctat agcatataca
    44401 atttatgctc taccattatt attttcatcc aatgaggttg ctatgaagtc aataaattta
    44461 ggactagaag aatcatcaag gagtttaggt gctggaagga taaaaacctt ttataatgta
    44521 atagttccaa atatgatgcc aggaataatt tcaggagcta tattagtatt cattcgtaca
    44581 attggggaat atacaatgtc agccttgctt tatggtgttt ataatagacc tatttcaatt
    44641 tctattgtaa ctaatatgca agaatttaag ataggagtat ctatggctta tggtgtatta
    44701 gtaattggta tatgctatat agcattagga ataattttta aattagatag aaaaagattt
    44761 acataagata acaaaggcta atttataaat tggtgcttag aaaaccaaat cactttatta
    44821 gctaaagatg aatttgaagg gtgacacttt ggtgttttat gtaaagttta tggaagtaaa
    44881 acattaaata atcgtgagta tgattcctat aaatcgtata tactattgaa atccaagaaa
    44941 aggtattggc taaatagcta atatcttttt aattttttga ctcccatata gcattaacta
    45001 ttacatgagt atctttaaat ttatagttaa agtatcttaa ttgtttatta taaaaatata
    45061 ggatggctaa agcacattaa attaaaacac ttaaaaagag aagatgtaca tgagaaatat
    45121 aattaactat gatacagact tctaaaaatt atttagtgaa aaggaactta gagtgtataa
    45181 taaaagttcc ttttcaataa ggaaaacgat tgttattttc tgagcttcat taccctgata
    45241 ttatttaaat ataaacaaca acaaaattaa caagaagtaa attcaaccta aaatttaaaa
    45301 tatcgggagg tacaatatgt taatcaatat gaaggaaatg ctaaaagtgg cacaagaaaa
    45361 tcaatttgct gtaccagcat ttaatatagg aagtgggcaa atacttaaag cagtagtaca
    45421 gggtgctaac gaaaaaaatg caccagtaat acttgcaata cacccaaatg agctaagttt
    45481 tctaggcgat agctttgtag ttagttgcat agaagaagca aataagagta aagtacctat
    45541 ggtaatacac ttagatcatg gggaaaataa agaacaaata ttaagggcaa taagatgtgg
    45601 atttacatca gtaatgattg atggctcaca tttaccatat gaagagaatg tagctatatc
    45661 tagggaaata gtagaaatag caaaaggatt aaatgtgtcc gtagaaggag aacttggaac
    45721 aataggaaca acaggaacat caagtgaagg tggtactgat gaaataatat atacagattc
    45781 aaaattagct aaggattttg ttgaaaaaac aggagtagac acactagcta ttgcaattgg
    45841 tacagcacat ggtatatatc caaaaggttt taaaccagag cttaaactag atttattaaa
    45901 agaaataaga gaagtagtag atataccttt agttcttcat ggtggttcat caaatccaga
    45961 tgaagaaata gcacaagcag ttaaactagg agtttgtaaa ataaatattt cgagtgatgt
    46021 taagtcggca tattataaga agtgcagaga actattagaa caaaacccaa gcttatatga
    46081 gccagatact atatatccac catgtataaa agctgcaaga gaagttatag agtttaaaat
    46141 gaatctattc aatgctatag ataagttaaa gtgcttttat aaaaataaaa attaattatg
    46201 aggtaacaaa ttaaaaggag gggagaattt atgataggta aaatactacg aagcgattgt
    46261 attgtactag ataaacaatt acaaacaaaa aaagatgtaa ttaattatat ggcaaatcat
    46321 ttgtaccatg gaaattatat aaataataaa gaaaagttta tagctgatat taataaacgt
    46381 gaaaaagaat catcaactaa tatgggtaat ttaatagcta tacctcatgc taagtcaaat
    46441 gtagtaaatc aacctgtaat gatgtattta agaacagata gagagattac agataatgat
    46501 ggtcaaaaac ttaggtcatt ttttatgata gcagttccag aatcaggttc agatgaacat
    46561 cttaagatta tatctaaact agctacatat ctaatggaag aaaattttct taagcatcta
    46621 ctaagtgcag aaactccata cgaaatatta agtatattta ataataaagc tgcagaatca
    46681 ggagatttta gtaataatca aaataaaggt cttatagttg ggataacagg atgtccaaca
    46741 ggtatagctc atacttttat ggcaaaaaaa gcattagagg aagcagggca agaacttgga
    46801 tatgaagtta aaatagaaac tcatggagct ataggtgtag aaaataagtt gactaaagaa
    46861 gatataaaaa gagctgaata cgtaataata gcttgtgata aagaagttca actgagtaga
    46921 tttataggaa agaaagtgct acaaaagaaa gtagtagatg ctaagaatgt ttcattagct
    46981 aaaaatttaa ttataaacgc tgaaaatgga atggctaaag aaattaaacc aggtggaaag
    47041 actttagaag attcaaaaga aatgcttcaa gggtcagaga caaagggtgt ttataagcac
    47101 ttaatgagtg gtgtatctga aatgattcca tttgtagtga taggtggaat tggtatagcc
    47161 atagcattta tgtttggtat atttgcatca gacccaactc atgaaacata caaccctata
    47221 gctggattct ttggacaact tggaggcgat tcagcattta agttatttat accgatactt
    47281 gctggtttta tagctaaatc aatagcagga agacaaggat ttcctcctgc tatgatagct
    47341 ggttttatgg cagttattgg aggttcaggg tttataggtg gtatggtagc tggttttgca
    47401 acaggatata tagctttagg agtaatgaag ataacagaaa atttaccaga tgtattaaaa
    47461 ggagtaaatg ctgtattgat atgtccactt ttgattgcat ttacgagtgg agctataatg
    47521 ttctttgtag ttaatacgcc agcatcatgg ttaaatgaag ctttacaatc ttggttacaa
    47581 agtatgtctg gaactaataa agtattatta ggtgcaatat tagcagggat gatggcatca
    47641 gatatgggag gacctattaa taaaacagct tcagcttttg gattggctat gttttcaagt
    47701 aatatatttg agccatcagc agcattaatg gtaggaggaa tggtacctcc attagcgata
    47761 tcattagcta tgttaatatt caaaaataag tttactaaag aagaaagaaa gtcatctcta
    47821 ccaactgcta taatgggggc atctttcata acagaaggcg caataccgtt tgcagctgca
    47881 gacccattaa gaatgattcc agcaaatata attggttctt gtataggtgg ggcaatctgt
    47941 atgagtttag atataacttt aatggcacca catgggggaa tatttgtaat accatttgca
    48001 tgtagtgcac cagttgcata tatagcttgt atattgattg gtacagtaat aacagcattg
    48061 attatagggg tagcaaagcc tactataaga agtgaaaaca gtgaagttga attacttggt
    48121 gcttaaatta taaataatag taaaaataag taatggaata acaacaagta tatagaataa
    48181 taataaggat atttagaatc agttaactac ttctaaatat ccttaatttt tattttgaaa
    48241 ttatattatc tattatatca atttagtaag gtgtatcata aattctttta tgatacagaa
    48301 gtatcttagt aattttacat agttagtaaa tatgttaaaa tagtacttaa tataaacata
    48361 gaaatatata aacataggta gggagggcta agtatgcttg tgtcgaggca aattgaattt
    48421 cttaaattga tactaaacga aaataaatat agacctataa aatactttaa agataaatta
    48481 aatgtatctg ataaaacttt acaaaaagat ttgaagatga ttgagaaata tttagaaact
    48541 tttaatataa aaattgatat aaaaagaggc tatggaatat taatagaaga tttagcaaag
    48601 aagaacatag acttaattaa tagtttaaat atacaatcga aggaaaataa atctttatca
    48661 gtagagcaga gaagaatgga gattttaaag tatttattac taaattcaaa taatataact
    48721 tcaataaatc agttagcaga taaatattat gtaagtaaaa cttctatagt aaatgatttt
    48781 aaatatatag aggcatggat aaaagaatac aatttaaaac ttaataaaac tttagaagga
    48841 actaagatta taggtaaaga agtggatata aggaaatcga ttgccaaaat gatggatgat
    48901 ttattagatg aaaattatga acaacatgat atatctgagt taacaagatt agattctgct
    48961 acatttagtg cattgataaa tttatttgat attgattcta ttatatttgt agaaactata
    49021 attacagaat tagaatacaa tttaggatat actataaatc agccctacta tataaattta
    49081 attacccata tacttatatg tttaaagaga atcgaagaag gtaatcaaat agaatctcag
    49141 gaagaaagag aaatttctgt agataatttg gacgagttag tatataaaaa tgtcactaca
    49201 cttatagata aaatagaaaa tagatacaga gtaaaaataa cgaaagatga aattatgtac
    49261 atatatattt ttttggtatc atctggattt agtagcgaaa ataatagtag ttataatgat
    49321 gaatcagata tattaagtga aagtgaaaaa gtttcatcta taatgataga gaatatgtca
    49381 caatttttaa atataaatct caaaaatgat gacttactac aaaaaagtct agcatctcat
    49441 gtaaggccta tgttaaacag attaagatat gatatccaaa taaaaaaccc gttgttagga
    49501 gagatacaag agcgattttc agatgtgctg ggattatgta tgatgactat aaatattatg
    49561 acagagtatg ataatctgaa gaatattagt atagatgaag tttcgtatct tgccacatat
    49621 tttcaagcgg caatagaaag aaatatgagt agtaaaagag taatagtagt ttgtcataca
    49681 ggatatggaa catctcagct ccttgcagcc agattaaaaa gagaatttcc tgaatggact
    49741 atagttgata tagttcctat gcatcagttg agtaagcgaa atttagatga tgtagacttt
    49801 gtaatatcta ctgtaaactt agatttgaaa gataaattac atatagttgt atcagtacta
    49861 ttaatggaaa gtgatattaa taatataaaa aatgctttac tttctaaacc taaaaaaagt
    49921 atgaacttag atacaaactt attaggaatg tatttagaag ataatatata ttttaatttt
    49981 gatgtagctc agatggaaag tttaataggt gtgaatttag ggagtaaata tgaatctatt
    50041 tcattaggaa aagatttgaa tatatatata cataagcaaa gtaaattaaa taaagggata
    50101 atgaatatca ataatgttac tagaacgatt gatatttatt tagaaattag taatcaaagt
    50161 tttttaaaga atattttaat ggaaatatca aatttatata ggcaaaagaa ctatataaac
    50221 tatataatag attgcaagag caaagaggat attaaaatat tatttaagaa taatctattg
    50281 gagaaaacaa atggaaatta gagaaatatt aacagaagaa agcattattt tagatttgaa
    50341 atcaactaca aaagaaggca taatacagga attagtagat aaattatacg atacaggaag
    50401 tataacttta aaaagtaagt ttataaaggc attaaaacat agagaaaaaa taggctctac
    50461 tagtataggt tatcaaatgg ccatgccaca tggaaaaaca aaatatgtaa agaaggcatc
    50521 catagtaata ggtaaatcta aaaaaggtgt agattggcca agtatagatg gcttacctgt
    50581 aaaggtaata attatgtttg ctatgccaca atctggaggc aatgaagata tgatattaat
    50641 atctaaaata gcttacattt taggtggtaa aaatataagt gaaagacttt taaatgtaca
    50701 tacaaaaaaa gaaatattag atatatttta tgaagtgtag gtattgtata aattataaat
    50761 ttgaggtttt taaaataaaa tgtgtattct tttaaatagt atagattaat ttttagacac
    50821 tagagaggag aggatatcta tggcaatata tttagaaatg cctaaattaa tacatgaatt
    50881 tccttttcgt agtctatcaa atgaaggaga agtattaaca acaccacact ggcataagga
    50941 aatagaaata ttacttataa cagaaggtgt agtaaatcta tttataaatg acaagcctat
    51001 gcaattaaaa aaaggcgaga tagtgataat aaaaggagga gatattcatt atatactgcc
    51061 atcaccggga agtgaaagat tagtatttca atttgatata tcttttttta atgatttaat
    51121 tttattaaat gaggaaaaag aaagcttaat taatttattc agtagtataa aaaaatgtag
    51181 tagagattgg tcagcaaaaa taagaaagtc agttttcgat atattgatag atatctacaa
    51241 tgaagaccta tacaaaatag aaggatatag ttatgcaata aaaggtaaaa tgtataattt
    51301 aattcctata ttatatagac agattcctag agaaattgaa gaaaatacag tagaatatga
    51361 aataaactct aaagagatat tagagagatt gaacaatata ttcaaatatg tagaaaaaaa
    51421 ttataaacaa cctataaaat tagaagatgt gtcttatgaa gtaggattta gtgtatatta
    51481 ttttactaaa tttttcaaaa aaaatacagg aaaaacattt ataacttttt taaatgaata
    51541 tagattagaa aaagcaaagt ggatattact taataacaat atatccattg tagatttggt
    51601 tgaagaagtt ggttttggaa gtacaaaaac tttttacaga gtatttaaag aaaaaattgg
    51661 agtctctcca ttagaattta aaaaaagata taatagcttg gagaaaaaag ggggtgcctc
    51721 aaaatgaact tagttcatga ggcactttct tttatatgaa atcaaatata ttttcagtat
    51781 ttcaacaatg aaaattccat tcatttataa agtctaaatt ttagttctca atacaatctc
    51841 tatttcgaaa taaatccttt tatatatata aatatacagc aatatatgag aataagataa
    51901 caataatgag gatataaaaa tgtatttgct atatatataa ttatatacat agatatctaa
    51961 tattgatatt taatatgaaa gtattgaaaa tagacaatat taattatagt gagtaaaaaa
    52021 tataattgga tttttaaatt gaattattta aaaggtatag tatgaaaaaa atcttataac
    52081 taaatatgag atagaaatta taaaacttta tactgtgaaa gaggtagatg catgaaatta
    52141 gggaaagatt ttttatgggg aggggcaatt tcagccaatc aaagtgaagg attttattta
    52201 gatggaggaa aaggtttatc tcagtttgat aaactcccat taaatgataa gagattaaaa
    52261 gatgtatgtt tagatgagga taatatttta aatgaaaata atcaatacta tccaagtcat
    52321 atagggatta aattttgtga aaattacaaa gaagatatag caatgttagc agaaataggt
    52381 tttaaatgtt ttagattttc tatatcttgg tcaagaatat tcccaacagg agaagaaagt
    52441 gaaccaaatg aaaagggatt acaactttat gataatataa taaaagaatt aaaaaaatat
    52501 aatatagagc cattaataac gataagccac tttgatatac cttattctct agttgaaaaa
    52561 tattctgggt gggctgatag gagagtggtt aatttatatg taaaatatgc tgaaattttg
    52621 atgaaaagat ataaagatga tgtcaaatac tggattcctt ttaacgaaat gaatatgata
    52681 attcatattc catatatagg tgctgggtta acttttatag ctgatgaaaa tcaacttcag
    52741 aaaaaatatc aagcagcaca ccatcaatta ttagctaatg caaaaactat agaaatagga
    52801 aggtatataa ataaagaatt taagtttggg tgtatgttag ctgctggaaa aacatatcca
    52861 tacacatgta aaccagaaga tgtatttgca actttagagc atgaaaggca taatttgttt
    52921 ttttctgatg ttcaagttag gggtgtgtat ccaagcttta tgaattatta tttaaaatca
    52981 aatcaaataa aattaataat aaaagaggaa gatttatcaa cacttaagga taatactgta
    53041 gattttgtat cttttagcta ttattctagt gcttgtagtt cagctagagc tgaaggttta
    53101 gaaaaatcaa aggcaaacgg accagaaacc ataaaaaatc catatcttcc aaaatcaaat
    53161 agtgtatggc aaaacgaccc tgtagggtta agaataacta tgaatcagtt atatgaaagg
    53221 tatcagttac ctttatttat agtagaaaat ggactgggta ctcaagatat tgtaaatgaa
    53281 gatggaaaaa taattgatga ttatcgtata gattacatga aagaacatat taaaaatatg
    53341 attcttggag taaatgaaga tggaatagag cttataggat atcttatgtg gggatgtata
    53401 gatgtaacca gtgtaagtga aggaaagatg acaaaacgat atggcataat tcatgttgat
    53461 tctgatgact atggaagagg ctcatttaaa agaactaaaa aacaaagtgc tttttggtat
    53521 aaaaaagtaa tagaaacaga tggagaaatt ttatttaatg atatggaaac tcatgcataa
    53581 ttcattttaa gaaaggagtg ttattatgag tttaatattt actactaagg accaacttat
    53641 agagcaaggg tttagtaagg atacaataaa atccaatgaa acgttgttta cactagctaa
    53701 tggacattta ggagttagag ggaatattga agagtccgat tttaataatg agtatgtaga
    53761 taatatgggt acatatgtaa atggatttta tgaagaatct ccaattacat atggagaaag
    53821 cgcttatggc tatgcaaaac aaaatcagac tatctgtaag ttacctaatg ctcatatagt
    53881 aaatttctct attgaaggag attgctttga tttatcaaaa ggtattacaa gtgaacatac
    53941 taggatacta gatttaaatg aaggaattgt taaacgttca tttatatggg aaaactctcg
    54001 tggtagaaaa gttaaagtat ctatagaaag attagtatca caagatatag aagaattaat
    54061 gatgatttca tatacaataa caccattgaa ttttaatgga aaaataaaat ttaaaaataa
    54121 aatggaaaat agtatggaga agtttaattg tgaaaaagta gatgacccaa gagtggcatc
    54181 tataaataag aagcaattta aaattaatgt aaaaaaatat aacaataagt attttatgaa
    54241 tttagttaca gaaagaagta gattagggtt atggtgtggg tttgattcat atattacttg
    54301 tggaaatatt acaaatgaga cctataatgt ttcagatgaa tgtattgagc gagaaataga
    54361 agtctatgcc aaaaaagatg aaaggttaaa tttagaaatt gttgtaggct atagtagagt
    54421 atattctgat ttaaatctaa atgaagaacg tttaaaatca ttagaatgtc tggagtcgtt
    54481 aaaatgttta gaatcagaag cacatttaaa atcattagaa ttggttttaa gagaagcatg
    54541 taatattgga tttgataaag tcaaaaatat tcagagaaag aaaatgaatg agttttggac
    54601 aacctctgat gtagagattg aaggcgataa aactcttcaa ctgggtataa aaaccaattt
    54661 atttcatatt tatcaatcag caggaagaga tggaaagact aatatatcag caaaaggtct
    54721 tacaggtgat ggctatgagg ggcattattt ctgggataca gaaatgtata tattaccatt
    54781 ttttatatat actcaaccat ccattgctag agctttatta gattatagat actcaatctt
    54841 agatgcatca agagaaagag ctagggaact tggaataaat aaaggttgct tatattcatg
    54901 gagaactata aatggtaatg aatgcagtgc atattatcca gcaggaacag cacagtttca
    54961 tataaatgca gatatagctt atggtattag aacgtatttt gaagcaacta atgatgaaga
    55021 atttatgatg caaaatggct tagaaattct tatagaaaca gcaagatttt gggttgaatt
    55081 tggagattat atagaattaa aaaataataa attctgtata aatggagtaa caggaccaga
    55141 tgaatataca gcaatagtaa acaataatta ctacactaat ttaatggcta aatataattt
    55201 aatatatgca gtacagatgg tagataaatt taagcataat ttattttcaa atgaagtatt
    55261 tagaaaagtt aaattacaag aatatgaagt aaaagactgg ataaatgccg ctcaaaatat
    55321 ttatttacca tatgatgaag agaagaaaat aagcaaacaa gacgattcat ttttagaaaa
    55381 atcagtatgg gattttaaaa atacaccaaa agaaaaatat ccattacttc tcaattatca
    55441 tccattaaca atatatagat atcaagtaaa taaacaagca gatactgtac tttcagcgtt
    55501 gcttttccct gatgagttta gcttagaaca aaagaagaga gattttgaat actatgaaaa
    55561 aataactact catgattcat ctttgtcaag gtcaatattt ggaatgatgg caagtgaaat
    55621 tggaaatcat gaaaaagctt ataactattt tatggacaca gcattaatgg atattaataa
    55681 cctacaaaaa aatacaagtg atggaataca tgctgctaat atgggtggaa catggatgag
    55741 tttagtatat ggatttgcag gaatgaaaat aaaaaaggat aaattaagtt ttgaaccaag
    55801 gatacctaaa cactggaaaa atattaaatt taatatatta tttagagata atttagtttc
    55861 tgtaaatata gaagaatata aatcttatta taagttaatc aaaggtaaaa acataagcat
    55921 attacatgat aataaagaaa taaaattatc aaagaacata atagaagtta ataattgttt
    55981 taaagggagt aattaatatg aaagcagtct tatttgatct tgatggagtt ataacagata
    56041 ctgctaagta tcattttgaa gcttggcatg agatagcaaa atcgctagat atagaaatag
    56101 atgaaacttt taatgaaaaa ttaaaaggca taagcaggga agaatcatta gataaaatat
    56161 tgttatctgc taataaagta gatagttata ctaaagagga aaagttaaag gtgtgtgaag
    56221 aaaaaaataa catttatata aagttaataa actcattaac atataaagat atattaccag
    56281 ggataaatga gcttataaaa gaacttaaaa aaaataatgt gaaattggga atagcatctg
    56341 ctagtaagaa tgcacctagg atattagaat ctttgggaat aaaagatgaa tttgattgta
    56401 tagtaaatcc atccttatta gaaaggggaa aaccatatcc tgatattttt attgaaggga
    56461 gcaagatgct aaatttaaaa caatatgatt gtgtaggaat agaagattct tattcaggta
    56521 ttaaagctat aaatgctgcc aatatgacat caattggtgt ggggaaaaaa gaagtactag
    56581 gaaaatgtga ccatattgta gaagatacta gcttattaaa ttacaataca ctattacaag
    56641 cttggagtaa aaagattaat ttggattaaa attatattaa aaattatttt aaaagagagg
    56701 ataaggtatg aagaataaat atgaagaagt agctcaattg ataattgatg gacttggagg
    56761 aaaggataat ataattgact taactcattg tatgacacga ttaaggttca tcttaaaaga
    56821 tgaaaagaaa gtcaatgcag ataaattaaa atctatagat aaggtagttg gagtaaactc
    56881 aacttcaact caatatcagg tcataatagg taatgaggta ggtgttgtat ttaatgcaat
    56941 aataaataag gggataaata ccacaggaga tattaaaagc gatataaaaa atgaaaataa
    57001 aaaaaatagt attttaaata atataataga tacaataact ggttgtatga cacctatgat
    57061 accagccctt acagcatctg ggatgataaa agttatatta tctctttgta ccacttttaa
    57121 ttggctatca tcaaattcaa gtacatatag agtattagat ataataggag atgtagcatt
    57181 ttactttatg cctataatac ttgcaataaa tgcagctaaa aaatttaatg ttaatacatc
    57241 aatagcagtt atagtagtag gtgtgttttt acatccaaat ttctctgcat gggtatcaag
    57301 tggggaccct atatcattta taggagtacc aattcaaggt gttatatatg cagcatctgt
    57361 tatccctgca cttttaacag tatggatgat gtcatatata gaaaaattca ttaataaatt
    57421 aacacctagc atgttaaaaa caattttaaa tccaacttta gtattattaa taagtgcgcc
    57481 aatagcatta atagtaattg gaccaatagg aaatttctta ggagagggat tagctagtat
    57541 aataaattta ctacaaggaa ggttaggatt tataatggtt tgtttattag cagctgcaat
    57601 gccatttatc gttatgacag ggatgcatca tgcattgact cctatattca tatcagcatt
    57661 tgcaactaca ggacaagaat cgctaatatt aatatctcaa gtttgtgcta atttagcgca
    57721 aggtggcgcg acattagctg tagcattaag aagcaaagat agtaagatga aacagttagc
    57781 atcagctgca tggatatcag ctatcatggg tataactgaa ccagctcttt atggagttac
    57841 attgaaactt aaaaaacctg ctatgttagc atctatagga gcaggaatcg cagggttatt
    57901 tgcaggaatt actcatgtga ctttatatgt tccacaaaat agtataatgg cagtacttgg
    57961 attatcaggg gaaaagggaa tttcaaatat agtaaatgga cttatagtta tatttatagc
    58021 attggttgct ccatttatta tgacatatgt ttttggagtt gaaaaaaatg ttaaggaaag
    58081 tacagataat gtagtagagg aagtataata ttaactattt acattaatag aatttttatt
    58141 attattgact ataacttgtt ttgtatttat attgatgcaa agaaataagt taatattaat
    58201 gataataatt attataactg acaaaaagca acacaaaaga ttgatgaagt atatggaaat
    58261 aaaaagttga caaaatatgt ctgatgtttt atcatattaa ttggaattag gtagtaattg
    58321 tttaagtaca agctaagctt attcattaat aatagcagta tcctaggaag gagtatgccc
    58381 attattatgg ataagctttt tttatgctta aaaggaggat aatcatgata attaataaga
    58441 tattaaacaa taatgttgta atcacattag atgataatga tgaagaagtt atcgttatgg
    58501 gtaaaggaat tggttatcaa aaatcaaaag gcaatctaat agataaaact aaagtaaata
    58561 aagtatttag aatatcaaat aaagaaatat caaacaaact acaagaatta ctcaataata
    58621 ttcctataga acacatgaaa ttatcaagtg aaattataga atacgcacaa ataaagttaa
    58681 acaagaagct aaatgaaagt atttacatat ccttaagtga ccatacatat tctgcaattc
    58741 aaagaatgaa agaaggaata aatgtaaaaa atgcaattct ttgggaaatt aaaagatttt
    58801 ataaagaaga gtttgaaatt ggaatgaaag cactagatat tattgaaaac aaaacaggta
    58861 taaaattacc agaagatgag gctggattta tagcctttca tatagtgaat gctcagttaa
    58921 gtgaaggtca tactttggca tctgatatta cgaagttaat acaagaagta cttagcatag
    58981 ttaggtatca ttttaggata gaatttcatg aagaatcagt gttttattat agatttataa
    59041 tgcatttaaa gttttttgcg caaagattgc ttttagatag tgcacatgaa ggtgagacag
    59101 acaaagaatt actaagcatt attaaatcta aatataataa agagtttgaa tgtgtagtta
    59161 aaattaaaaa tttcattaaa aaacaatata actacatatt aacagatgat gagcttatat
    59221 atttaacaat acatttagct aaagtagtta aagactcaaa tatgtaagtg aaataatttt
    59281 tcagtagtat attaagaatg attgaaagga gtgatactaa caaaattata cctatggttg
    59341 gatggtaaca ttgagttggc caaaccttca aatttcaaaa aattaattta aacgaaatat
    59401 ggaggagaaa aatgggaaaa tacaaacaat tagcacaaga gatagtaaac aatgttggtg
    59461 gaaaagaaaa tattagtgga ttagtacact gtattacaag attacgtttt actttaaaag
    59521 atgaaagtat agcaaatgac aatgtattaa aaaacatgga aggtattgtt actgtaatga
    59581 aaagtggagg acaatatcaa gtagttatag gaaatcatgt tgaagctgtc tataaagatg
    59641 tagttgaaat aattggttta gatgattcaa gtacaagttc agaaactaaa aaatcaggta
    59701 atatactaga taaaggtata gatataatat caggaatttt tcagccagtg ttaggaataa
    59761 tggcagcttg tggtatgctg aaaggattta atgcattatt tgtagcaatg ggattatata
    59821 gtgatgtatc tggtggttat atggtaataa atgcagcagg agatgcatta tttacattcc
    59881 ttcctttgtt cttaggatat acttcagcta agaagtttgg attaaaacca atgttgggat
    59941 tagcactagg agctgcagta tgttatcctg ctatacaagg tagcagtata tcagcaggag
    60001 cagatgtgat gtacacttta tttaaaggaa caatgtttgc atcaccagta tatattgatt
    60061 tctttggact accaattgta tcaattgatt atactggaac agtcgtacca attatattta
    60121 tagtgtattt tgcttctagg tgtgaaaaat tatttaataa gtttgttcca gatttagtta
    60181 agtttttctt tgtgccaatg cttacattat taataacagt gcctgttgca cttatagtta
    60241 taggtcctat cgcaacattt ggttctacac ttatttcaca aattgtaatt tcaataagag
    60301 attttagtcc actattggca ggtgctatag tagggtttac ttggcaaatt cttgttattt
    60361 ttggtatgca ctggggattt attcctgtat atataaacaa tgttatgact ttaggatatg
    60421 ataatgttat gatgccattc tttgcttgta catttgcaag ttcggcagtt gtgttggcaa
    60481 tatttttcaa gactaaagat aaaaaactaa aagagatgac aataccaaac tttatatctg
    60541 gtatatttgg agttacagag ccagcaattt atggaatatt attgccttta aagaaaccat
    60601 ttataataag ttgtattgct agtgggattg gaggcgcttt ctacggattc tttaatctta
    60661 gaaaatttat aactggaggt atgggaatat ttgaacttcc agcaatgatt gaaccagatg
    60721 ggggaatggg caacttaata gtagctcttt ctggtatagc tatatcaatg gtcgtagctt
    60781 ttgtattaac tatgatttta tataaagatg agaaagtaga agagtctaaa aaagtaagaa
    60841 ataaggggaa agaagaaata aaagaagtca agtctactaa attagaaaga gaaatagtag
    60901 caagtcctat aaaaggtgaa gtattaaaat taagtgatat agaggatgca gcatttgcat
    60961 ctggtgtact aggtcaaggg gtggcaataa tacctagtga tggaaaagta gttgctccag
    61021 tagatggtgt agttacaacc ttatttccta gtctacatgc tatagggatt ctttctgata
    61081 caggtgttga agtgcttatt catattggat taaatactat tcaattagaa gggagaggtt
    61141 ttgaggcatg tataaaacaa ggtgatagaa ttacaaaagg tcaaactata ttaaactttg
    61201 atgttgatgc aataaaagag ttggggtata gtactgtaac tccaattgtt attacaaatt
    61261 catcacaatt tttagatgta gtagaaacag aaagtaaaaa tattgaatta gaagataatc
    61321 taattacagt cttattttag taaaaattga ggcattagca taagctagtg ctttggttat
    61381 aatttaagga ggctttgact atgagtttta aggatgattt tttatgggga ggagctactg
    61441 cagccaatca atgtgaaggt ggatacaatg aagacgaaag aggattggca aatgtagatg
    61501 tatgtccaac aggaaaagat agaacagcag ttattacagg gaaactaaaa atgtttgatt
    61561 ttgatgatga gcattattat ccagctaaaa ctggtattga tatgtatcat aattataaag
    61621 aagatataaa gttatttgct gaaatgggat ttaaagtata tagaatgagc attgcatgga
    61681 gtcgaatatt tccaaaaggt gatgaagaaa caccaaatga aaagggactt caattttatg
    61741 aaaatatatt taaggagtgt aaaaaatata aaatagagcc tttagtcact attacacact
    61801 ttgattgtcc aatgcattta gttaaaaagt atggtgcatg gcgtaatcga aaaatgatag
    61861 gtttctatga gaaattatgc aatgttatct ttagaagata tagaggatta gtgaagtact
    61921 ggctaacctt taatgaaata aatatgattt tacatgctcc atttatgggt gctggtattt
    61981 gctttgaaga aggtgaagat gttgaaaaga taaaatatca agctgctcat catgagcttg
    62041 tagctagtgc aattgcaact aaaatagcac atgaagttga ttcaaataac ttagttggat
    62101 gtatgtttgc agctggaagt gtatatcctt atagttgtaa tcctaatgat gtatgggaag
    62161 ctacaaagtt agatagagaa aattacttct ttgtggatgt acaatctaaa ggtaaatatc
    62221 ctaactatgc gttaaagtat atggagcaaa aaggtattac accagaaatg gaacctggtg
    62281 atattgaatt attgaataaa tatacagtag attttatttc attttcatat tacaatagcc
    62341 gttgtgttag aactgatgaa aatgcagatg atatggctga aggaaacata tttacatctg
    62401 ctaaaaatcc atatctttca tacagtcaat ggggatggcc aattgaccca ttaggtttga
    62461 gaattacact aaatcatgta tatgatagat atgaaaagcc actatttatt gtagaaaatg
    62521 gattaggtgc taaagatata gctgatgaaa atggttatgt agaagatgat tacagaatta
    62581 attatctaag agaacatata aaagctatgc atgatgcagt ttctatagat ggggtcgatt
    62641 tattaggtta tactacatgg gcacctattg atttagtaag tgctggtaca ggtgaaatgg
    62701 aaaagcgtta tggatttata tatgtagata gagataatag tggtaatgga agtctaagaa
    62761 gaatgaaaaa gaaaagtttt gaatggtata agaaagtaat tgcttcaaat ggtgaagatt
    62821 tatattaaac aagaaatcta tgttaaataa gaaatttgta ttaaataaga agagtataaa
    62881 aattaataat aagtataatt tttaactttt ttaactatag aaaatcaata cagaattatt
    62941 ttacattgta tttatgcaat agtatgattc acaaataaaa ttttagaaaa taaaattgtt
    63001 aagaagtatg ggaagtaagt gcaatttact ttgtaataaa agatgaaaaa ggcgagctta
    63061 ggttttaagc ttgtcttttt tattatgtat aaactatgat actttaaaat tctatgaaaa
    63121 atttatttaa tagagaaatt aaaaatttaa tggtaatcaa attctttacc aatgaatata
    63181 aaaaatgtct acgtgttata atagtttaaa ctaataaacg aaaggtagat gaatgaatat
    63241 gaaataccaa catataatag aagttgacaa agaactttgc attggatgtg ggctttgtaa
    63301 aaatgattgt ccagtaaaca atataattat agaaaataaa aagtcagtaa ttaaaaaaca
    63361 agattgtcta atgtgtggac attgtgcagc aatatgtccc acaaaagcta ttaccttgac
    63421 aggatttgat gaacctccta tagaacttac aaataagcca aagctagatt cagatgaatt
    63481 actaatggca attaaatcta gaagaagtat acgtaaattt aaagacaaag aagtttcttc
    63541 agaaattgta aagcaaatta ttgaggcagg taggtatacc cctagtgcta aaaattcaca
    63601 agatgtatca tatattgttt tagacaataa aaagtcaatt tatgaaaacg aagcagtgaa
    63661 attttttaga aaaataaaac ctattgcaaa tatagctatt aaatattcaa aagaagttga
    63721 gattgacgat aactttttct ttaagcatgc tcctattgca ataatgataa ttacaaaaga
    63781 taagattagt ggttcacttg cagcatcaaa tatggcatta atggcagagt cttatggtct
    63841 aggtgtttta tttagtggat atttttcaga tgtagcaaat aattcgccaa aattaaaaaa
    63901 gcttttaggt ctaaaacgca gtaatcatgt tcttacaaca ttagtaattg gatacccaga
    63961 tgttaaatat agacgtactg cacagaaaga agtagcaact gttagatact tataagagag
    64021 ggtggatttt atggaaaaag aatgtcaaca aagaatgcaa gaaataacat ctaaatttaa
    64081 agaatgtcgc aaagctatct ctgctatggg tgatgagact agacaattga ttttaattgc
    64141 tctcttagag agtgatttta atggtatacg agtgggagaa atcacaaaaa aaacacatct
    64201 ttctcgtcct gctgtatctc atcatcttaa gatattaaaa gaagcagaga ttgttaattt
    64261 gcgtagagaa ggaacgaaaa attattatta tcttgattca aaaaaatcac aatggaagtc
    64321 actaacagag ctaataaatc ttatatttgt tggaatacaa catattagtg aaaatgatat
    64381 aagaaaaggt gattaaatta tacttgattt aatacaaaaa gattgattta ggaactaaaa
    64441 agttcacttt gagacactat cttttgaact atacccatct taggagacag ttaaaatatg
    64501 taaaactgta taaaacaatg ggtatagttc attttataat ggtttaaata ttaagaatat
    64561 attattctaa atagtatctt tctctgtttt gagttttatt tttatactca atagcttcag
    64621 tggggcaacc acaaatacat gccatacaat gagtacagct atttttccaa actggctttt
    64681 tgttttttaa attaatatta tttaaaggac atagctctac acattttcca cagccaatgc
    64741 atttatcagt ataatgaaat cctttggcac taataattgt cttataaaaa actgtattta
    64801 ttataccact tttaattgta cctcctaagc cactaggagt aatagtttca aattcatttt
    64861 cattgcgtat atcagaaata atcctatata tttgtttatc tgcttcttta atcatttgtt
    64921 ttgatgtttc tttgtctgtt gtagaaaata aagctatata attctctggc attttaattt
    64981 ctgccatacc ttttaattgc cattccttgt atttacatag tttttgaata tagtttatgg
    65041 attttgctgt atctccccca caagtcatta caaagtaaac tctgttgtct cctagaaatt
    65101 ttgtttcttt tataaaatct gtaaccacta ttggcaatct ccatgcataa gtaggacata
    65161 cgaatatgaa tggtttacct gctgatatta attcatctgt tttttcctct tttataagtt
    65221 gatttagtga tatcagttca tcatttaatt cttgtgcaat tttacgagcc acatatcggc
    65281 tattaccagt accgctaaaa tataaaatca taataatatc tccctaacta ttttttattt
    65341 taactcttaa ttttttattt attatagtac tttattgaaa tattctattc aaatgtatgt
    65401 aaaatttagt agttaagaaa attataacac attagtaatt tttatattca ttggtaaaga
    65461 atttgattac cattaaattt agtaacaaaa tatcaactgg atttttatat aagaagagat
    65521 agtaattttc atgtgaaaga ttgtaaatat aaagatgatt ttgaagggca ataagaagat
    65581 aaaattgata gcttaataaa aaatatttaa cttttatatt aactgtttta aatattataa
    65641 ttatctatct tgaataatca accatagaag actgtataca aagacaaagt tgtgtacagt
    65701 cttttttata aatttaatgt ctataattaa atacactatt aaaatcaata agttattatt
    65761 tcaaagtagt attatccaaa tttttatgat ggttaataca atttgttagc cattttatag
    65821 caccttgttc cctgataata gctccatcaa gaactatata atcaccaaaa tcattactat
    65881 caagaggagg aacttcacta taacgctcca tttgactgta caagaacgta attctttctt
    65941 ggtgttgaag caattgatgc tctagtaaaa taagcctagt atctatatct aaattattag
    66001 aaaaatacat tctaagacga aaaatatcct taggggttct ttccattggc tcatcctttt
    66061 caagccattt caagaactca tctttacctt tttctgtgat tgtgtataac tttttctcta
    66121 atacatcacc actaatttta atatcatata caataagctt ttcatttacc aattttttta
    66181 gttcaggata tatttgacta tgctttgcat tccaaaactc agctaattga aaattgaact
    66241 cctttacgat atcataacca gtcataggat ttctatttaa taatcctaaa attgcatact
    66301 ttaaagttcg cataaataca cctctttctt taattacata cttattataa cacgatatat
    66361 ttagtttgaa ttaattaata tagctatgtt ttaataagaa cttttaaatt atgaggaaca
    66421 aaaaataaat aaaactatat ataaaaatga aattatgtaa atataaacat gtaagtattt
    66481 acatgtttat atttacatat agaaaaaatt gtgataatct taactaagaa attctattta
    66541 ataaatttat cgaggaggag agtaatgaat ttaacacaaa aaagatggat tatattaatt
    66601 gcaagttgtt tcatcaattt atgtattggt tcaatatatg cgtggagtgt atttgcatca
    66661 cctatggcag aacatttaaa tagtcttgct ggaacaactt ttacagctgc tagtttagca
    66721 attgtattta cagttacaaa ctcagttgga cctattacta tgattacagg gggaatgata
    66781 aatgataaat ttggtcctaa aaaagttgta tttgtaggag gattaatttt tggtataggt
    66841 atgatattgg caggtttctc aaaaggattg cctatgttga ttttatcata tgggataata
    66901 acaggtcttg gggttggcat ggtttatgga tgtacaataa gtaattcaat taaatttttt
    66961 ccagataaaa gtggattagt tggtggtata acaacagcag cttatgggtt tagttcagta
    67021 ataatgcctc cagttgctaa ttggataatt aataaatatg gagtaacttc tgcatttaaa
    67081 tcaataggtt tagtatttct tataattgta tgtgtttctt ctttctttat caaaaaatgt
    67141 ccagcagatt tcacaccaga aggatgggta ccaccagaga aaaaaggaaa agtaagagtt
    67201 gttattaata aaaattggaa agaaatgctt tcaacaccta tattttatct aatgattata
    67261 atattaactt gtggagcttt ctatggatta atgtgtgtgt cattagcatc ttctctagca
    67321 acaaatatga ttgggatgac aagttcagat tcagcaatag tggtttcaat tttagccttg
    67381 tttaatacat taggccgtat tgttgcagga tatatatcag ataaaattgg tagaataaat
    67441 actttatcag gtgcattagt tatttcaatt tttggtttat tatgtttgtt attctcaaga
    67501 gaaggagatg tagcaacatt ctatattgga ataataatta taggtatatg ttttggttca
    67561 tttatgggaa ttttcccagg atttacagta gataaatttg gacctaaaaa taatagtgta
    67621 aattatggaa tcatgtttat tggttttgct tttgcaggat atattggacc tgcagtgatg
    67681 aaaaatgtat attctgtaga tggcaattat caaagggctt tcattatagc tataattata
    67741 gctttaatag gttttatatt aacattttta tataaatata taaataaaat acaaaattta
    67801 aagatagaaa atttaataaa gggagatata aaaaatggaa agaaaatatc caaatctatg
    67861 taagccaatt aaaattggaa atgtaacatt caaaaacaga atgttttcag cacctatggg
    67921 gggaacagac ataacagcag attgtacaat tggctcaaaa tcaacagcct tttacgaatt
    67981 aagagcaaaa ggtggagcag gtgcagttac aattagtgaa tgtatggttc atccagaaac
    68041 agatggttca catgcatatc atctagactt aaaaatagtt gattccttag caagttttac
    68101 ttatacagca gatgcaattc gccgtcatgg agcaatacca agtgtagaac tatctcattc
    68161 aggacaatat tcaggaactt atttagttga caaagataag aagcgaggat tatcacaatg
    68221 gggagtaagt cctagtgttc gtcctgatgg attagagata aaagaactta cagaagaaat
    68281 aattgctgaa atagtagagt catatggaaa tgttgcagca ttggctaaga gagcagggtt
    68341 tgagatgatt atgattcatg gtggacatgg ctggctaatc aatcaattct tatcacctta
    68401 ctttaataaa agaactgaca aatatggtgg ttctttagaa aacagagttc gttttgctaa
    68461 agaagtttta gatagtgttc gtaaagcagt aggtccagga tttccaatag agtttaggat
    68521 gagtggttct gaattatttg agggagggta tgatttagat tatggaacag aaattgctaa
    68581 attattggaa tcaagagtag atttacttca tgtatcagca ggtacatacc aaagagggtt
    68641 tgcagtaaca catccttcta tgttcttaga acatggatgt aacgtatatc ttgcagaaga
    68701 aattaaaaaa catgtaaata ttccagttgc tactatagga gcattaaatg acccagaaat
    68761 gatggaagag ataattgcta gtggaaaagc agatgttatt tacatggctc gtgcattact
    68821 agctgaccac gaattaccaa gaaaagttat gagtaatcaa gatgaaaaaa tagtgaaatg
    68881 cctaagatgc ttcacttgta tggcagaacg tgctaccact tctacaagac gctgcactgt
    68941 taatccactt attggacgtg aattagatgg aactgaagtt gtttcagtat taaaacctaa
    69001 aaaagtatta atagcaggtg gtggaccagg aggattgcaa gcagccatta cagctgtaaa
    69061 gcgtggacat aaagtaatac tttgtgaaaa aactaatgaa ttaggtggaa ttttaaaggg
    69121 agaacaagca cttccattta agtataaaat gtatgaatta ggaaatactt ttggaaaaat
    69181 agcaaaagat ttaggtgttg aagtacgttt aaatacaaca gttacaaaag aatatgttga
    69241 aaatgaaaat gtcgatgcat taattatagc agtagggtct gaacctcttg ttccaccaat
    69301 agagggtctt gatggagaaa atgtagtaat agttaatgat tattacgtag aaaaagaaaa
    69361 agtcactgac gaagtaatag ttttaggtgg aggattagca ggatgtgagg ctgcaattca
    69421 cttagctcaa gaagagaaga ctgttcactt agtagagatg agagcagaac ttgccccaga
    69481 tgcaaatata aggcatcgtc caatattatt agaagaaata gaaagacaag gtatatatgt
    69541 atatacagaa cataagggtt taagtgtaac aacagaaggt gtagtatgta tgaataaatc
    69601 tgggaataaa ataaatattc caggaacctc agtaatatgt gcacttggac aaaaaccaag
    69661 aagagaagtg gtagacactt tacttgattc tgctccatat gttgctcaaa ttggagactg
    69721 tgttcgtgca tctacaataa caaatgcagt ataccaaggg catcatgctg cgctagatat
    69781 atagttaaaa agacgtagat agtattgttt tattataaaa aaggagtgtc tcaaaatgaa
    69841 ctttttagtt catgagacac ttttttacat gaaattaaat atatttttat catttcaaca
    69901 atgaaaaaag attatcttta ttttgagaca gcacttttgt tattatgatt ttaattctta
    69961 ttgcaagttt tcatttgatt gatgagtaaa actttttaag atgtagaagt atttaacaat
    70021 gtaaatgacc ctaacttaaa tactttagcg aaggttgaca gatttgtgtt tgcttttatc
    70081 tattataact taaggaaaca tgttacctga acaataaatt tatataataa aagtatataa
    70141 atatatatat gaatgttaag attagttgat agaatttaaa taataaatcc aatattataa
    70201 acataggagg tatgaaaaat atgattaatg agaatttaaa aagtctaaga aaaatccacc
    70261 agtatacaca agaagaatta gctgaaaaac ttaatgtttc tagacaatca atagcaaaat
    70321 gggaaagtgg agtttcccaa acaaaaggat attactgaaa taacctgtgt ttacctgctt
    70381 gtagagaaaa gaatattgct attaagccag agatactaca taaatgtgtt ggtatctctt
    70441 tttcgttaat gcaacacagt aaattatttc attttcctaa ttattttaga ctgataagta
    70501 actttttaaa tgaagaaaag aaatgacaat acttaaagga gcatggtata cttaaaggag
    70561 aatttcatta aggaggaaaa agagattgtt taatctaata gaaatgttat ttcctataat
    70621 gtttatactg atttttataa taattgtttt cacttttgtg aaaggaatag ctacttggtt
    70681 taaaaacaat aattctcctc gcttaactgt gtcagcaaga atagtagcaa aacgtcagaa
    70741 taccactcat aacaatcaac caaacgctgg tgatatatca ggagcacatg gatttcatac
    70801 aatttccagc acctcgtatt atgtgacatt tcaagtagat agtggtgata gaatagagct
    70861 gtctgtatct ggctcagagt atggagtgct tgcagaggga gataaaggac agctgacatt
    70921 ccaaggcaca agatatttaa catttgatag ggaaaattga atttagaggt gcattatgaa
    70981 taagtttttg agtcagataa ggcgtataga taatgaaata tctattacta ggaaaattat
    71041 aaatacaata tttatactgt gttttggaat agttttagga acttttgcaa aatttttaga
    71101 tactacagca agcaatactt taccatttat atttgaatat ttagatatta gtaatttttt
    71161 tggtcgtttt gctatatggt tattgattgc tttgtacatt gcaatttata gtcattcttc
    71221 cataagagca tcattaaatg tgttagtatt tttcattgga atggtttcaa gttattacct
    71281 atattcgtat tttgttgctg gattttttcc aaaaaattat gcaatgattt ggcttggttt
    71341 tactgtcatt tctccattgt tagcttttat ttgttggtat gctaagggga aaagcaaaat
    71401 atcttttata ctttcagtaa taataattgc aattttattt aattttacat ttatttatgg
    71461 ttggatttat tttgatgtgt attcaatttt agaagtgata gtctttggtt gtgcattaat
    71521 agctttaaaa cgtaacacct ttagggagac aacgtatatg atattgagtg cagttgttat
    71581 tgctgttata cttaatatgt tagttccatt tcattttggt taggcagatt ttaagattat
    71641 tatagataga atataaattt cacgaaccgc cgaagcgatc cgccagcggt ggcggtcgta
    71701 agacatatcg ccacgccagc ttgctggcga ggtggcggtt cactttggcg gtttggcgag
    71761 cctgcgagct ttctaagccc ccgttatcta acaggggggg actattacaa aagacaagag
    71821 caaaaacaaa tataaaactg ctgatatgca acgatttata aggttgtaag aacttatttc
    71881 actttacacc ctattctttc tacccgacag gtctaaaaca gcatatcaat agaaaataaa
    71941 tataagatac aaggtgtatg ctcctatgag tatatgcctt tttttgattg gaggaatgaa
    72001 gcatgaatga tatgaaattt attgaaacat taaagcaaaa gagaaatgtc tgtgattatt
    72061 cgcaatcacg actggcacag gaactacaaa tcaacaggca gaacttaaat gaaattgaaa
    72121 acggaaaaac aaaagccagt aaagaaatga aacatatact cttacattat cttgattatt
    72181 gtaattgtac acagcctttc actttaacga ttgactatct gcgtgttcgt tttcctacca
    72241 cagacgcatt ggaaattata aaaaatgtgc tggcaatgaa aagcgaatat tttatacatg
    72301 aagattacgg aatgtatgct tatgaagaac agtatatcta tggggatatt agtgtaaatg
    72361 cttctaaaga tagttctatg ggtgttttat tggaattaag aggtatgggg tgtcgggact
    72421 tagaatatgt tttacaggta agagggatag actggtattg ctttttaaga tgttgtatag
    72481 attatcaagg tgtttttaaa cgcatagatt tagcagtcaa tgatatgggc ggattgctgg
    72541 atatagaaat tctaagggaa cgttattatg ctaacaaggt atggaaacgt tcaagaaccc
    72601 atgaagcagt agacagcgga aaattatcgg gtacacatgg agatactgca aaaacttttt
    72661 atatcggttc aaagaatagt tctatctact tttgcttgta tgaaaaagaa aaggaacaaa
    72721 aaagcaaggg tataaaaaca gatattaaga accgcttcga aattcgttta aaaaatggaa
    72781 aagcaggaca aacggtagag caacttgttt tttcaagaaa tcccgaacag accatagcaa
    72841 gctttattct cacacagata gattttcccg attatatttt atgggatata tttttagata
    72901 atgtaacgac ctcacttccg tttattatga cacctgttgc tgttaatatg gataaaataa
    72961 aacgctggct agaaagacag gtcatgccct ctttattgat gataaaagag attgaaaaga
    73021 aaacaggagc aaattatctg gaagaaatcg acaggcatac aaggctaaca gaaaagcagt
    73081 aattaaagat taaacaaatg acaacagaca tagcagatat gattgagaaa gataccgctg
    73141 ttccacaagg gaatgacggt attttttaat ttcttcaaaa aaactgcaac aaaatgactg
    73201 cttgtgtaca gatatggtgc gaggaaagga aatctaactt tttttgaaaa caggtcatta
    73261 aatcggtggc tgctgtccct atatgatgtg aaagaagaaa cgatttttaa tttcaactta
    73321 acatttgaca gttttcattc cctatatgga gcaaagaaaa tcttttattc catagttggc
    73381 agttacggtg ttgcatgggt agttagggtg tgaaaagaaa aacagatttt tttcatcacc
    73441 aacttagcaa actgatactt gctttcccta tatggtgcag gaaaagagag tttaactatt
    73501 ttcatttcaa cttagcaact ggacgtttgc tgtacagata tgtagtgaaa agagaaaaag
    73561 ttttgaatat tggttacgct tcggctcttt tccaacgcgg tatataggaa agacgatttt
    73621 cttctttcat gttctttgac aactgaataa agcaattcaa tacgtttgac agacagcgat
    73681 ccattgaagc agatacgcca tgaccttttc cctgcaaaag cgagcgaacc ctatttgtgt
    73741 tcctgtaaaa gacttgtcct cttttatcgc catgacctgt tctgtctgat aaatgatact
    73801 cccgtacagc cacagcttga acgttcagag cgtcgcacgc aatgggtacg gctacataag
    73861 aactatgcag aggtggaatt cctgtgggct atgacaaatg ccgttgaatt gcttagaaaa
    73921 aagattatgg aaagggggta tgtgttattg ctgatattgt aaaaacaatg caagaaaaga
    73981 caaataataa gcgtagcatt ggcaacagag gaaaaacaaa gattgttgta aaagagcatt
    74041 tttccgaaaa gggaaagaca atggaggaac ttctgactga tgttatgctg gaaaaagcaa
    74101 agcagacaat cgcataaaat tggtgcagtt gtaagacata gattgaatgg caaaaagtac
    74161 ccgtgttata ctttacttgc aagcaggtat tgtaaacacg ggttagttat aaaggaggat
    74221 aactgacaat gaaacaacag atttacaata ctgcacttta tcttaggtta agccgagatg
    74281 atgaattaca gggcgaaagt tccagcatta ccacacaaag aagtatgttg cgtctatatg
    74341 caaaagaaca tcatttgaat gtgattgatg aatatattga tgacggctgg tcgggaacaa
    74401 attttgaaag accgagtttt caaagaatga ttgaggatat agaggcagga aaaatcaact
    74461 gtgttgtaac gaaagacctt tcccgacttg gcaggaacta tattatgaca ggacaatata
    74521 cagaattgta ttttcccagc cataatgtcc gttacatagc gattgacgac ggtgtagaca
    74581 gcgagaaagg cgaaagtgag attgcaccat ttaagaacat catcaatgaa tgggtggcaa
    74641 gagatacaag ccgtaaagtg aaatcggcat ttaagacgaa atttgcagag ggtgctcatt
    74701 atggtgctta tgctccatta ggatataaga aacaccctga catcaaagga aaactgctgg
    74761 ttgatgatga aacaaaatgg attgttgaaa aaatcttttc cctagcctat caaggttatg
    74821 gtagtgccaa aatcacaaag gtactgcgag aggaaaaagt tccgacagcg tcttggctga
    74881 attttacaag gtacggtact tttgcacata tctttgaggg aaagcccgaa agcaaacgtt
    74941 atgagtggac gattgctcat gtcaaggcaa tcttaaaaag tgaggtttat ataggcaaca
    75001 gcgttcacaa tatgcagtct acggtttcat tcaagagcaa gaagaaagtg cgtaagcccg
    75061 aaagtgaatg gtttcgagtg gaaaataccc atgaaccgat tattgacaaa gaagtgttct
    75121 atcgtgtgca ggaacagata aaatcaagac gtagacagac aaaggaaaaa gcaacaccga
    75181 tatttgcagg gcttgtcaag tgtgcggatt gtggctggtc tatgcggttt gcaacgaata
    75241 cggcaaataa aacgccttac agttattatg cttgcagtta ctacgggcag tttggcaaag
    75301 gtacttgttc tatgcactat atccgttatg atgtgttgta tcaagccgta ttgaaacgat
    75361 tgcagtattg ggctaaggca gtacagcagg acgaagaaaa ggtgctgaac aagatacaga
    75421 aagcaggcaa tgcagagcga atacgggaaa agaagaaaaa ggcaagtgcc tttaagaaag
    75481 ccgagaaccg acaaaatgaa attgaccgtt tgtttgcgaa aatgtatgaa gatagagcct
    75541 gtgagaagat aacagagcga aattttgtga tgttgtctag caagtaccaa aaagaacaaa
    75601 tagaactgga acagcagata accaacctaa gagaagaatt aagtaaaatg gaacaggata
    75661 tgataggtgc tgaaaagtgg attgagttaa tcaaggagta ttccgtacca aaggaactga
    75721 cagcaccgtt attaaatgca atgatagaaa aaatccttat tcatgaagca ataacgaatg
    75781 aggataacga aagaatacag gaaatagaga tatattaccg atttattgga aaagtagact
    75841 gataaagagg gttcatatct ttaactaagg gaaactggag aatctattcc tgatataggt
    75901 agttgcatta aacttgcaaa attgtacaag gtcaaactag atgacttagt taatcattcg
    75961 gaagaaaaaa caggtattat agtacctcct aaaggaaagt ttttctttgg agcagtagta
    76021 gttggtgaac gtggtcagat tgtcattcca aaagaagcaa gagaagtatt taatataaat
    76081 gcaggagata aattattggt acttggagat gaggaaagag gattaggaat tgttcatcaa
    76141 cgtgatttga taaattttat aggtcatatg ggagtagtac gtaaagaaga atgattttaa
    76201 aaaattataa aaggaggtat gaaatgtgag taaaatagta ttttttagca ttcttgcata
    76261 tggtcatact aatcctacta ttgaagtagt tcgtgaatta gtggatagag gaaatgaggt
    76321 attgtattat tcttttaatg aatttaaaga taaaattgaa ggtgctggag caaaatttat
    76381 ttgttgtgat aaataccttc cagaattact ccctggagat gagaaaaaaa ttggtaagga
    76441 ttttcctgga ttaattgaga tgatagtaga tactactatt tctttagatg aaaaagtttg
    76501 tagggaactt aaagatttta atccagattg cattgtatca gattcattaa gtttttgggg
    76561 aaagttattt gcacaaaaac ttaatattcc atatgtatgc tctacaacaa cttttgcatt
    76621 taataaacat acagcaaagt tgatgaaaca aaactttata gaaattatac gtatgatttt
    76681 tggtgtaaga cgcattaata aaaaaataaa gcttttacaa agaaaagggt atgaagtaaa
    76741 aaattttatt tctatagttt ctaatgataa tgatacggat accattgtat atacatcaaa
    76801 agaatttcaa ccaatggtag aaaccttctc tagtaagtat tcatttgtag gtccatcagt
    76861 atcaaagttg attattaaac ctaaagagag aaaaagaaag ttaatatata tttcgcttgg
    76921 tacaattaat aataaaaatg ttagctttta taaaaactgt ataaatgcat ttaaagattc
    76981 tgatgttgat gtgattatgt ctgttggtag aagtactgat attaaaagtt taggaaatat
    77041 accaaataat tttgaggtta aaaatagtgt tgaacagatt gctatacttc aaaaaactga
    77101 tgtgtttatt actcattctg ggatgaatag tgttaatgaa agtttatatt atggagtacc
    77161 catggtatta tttcctcaac attcggagca gagaatggta gctaagagag ttgttcattt
    77221 gggagcagga attatgttaa aagaggataa gtccgaaagt attaaaaaag cagtatttca
    77281 agttataaat gacaatgaat ataaagaaaa tgcaactaaa ctatcaaaaa gcttttataa
    77341 tgcaggaggc tcaaaaaaag cagcagatgt aatattacag attatatgta atagtagaca
    77401 agttgacata taatagattt gttaaaaata tatatacata catgcaattt aatcaaagta
    77461 ctgacagtgg ggtcttttaa cctaccagtt ggggcatata tattgatgct aaatatgagg
    77521 gatgttatat tttaataaaa aagataacat ccttttttta gtgcgttata tcaagtttta
    77581 aataataaat gaaggaggat taatatgaaa aaatataaag ttatttttat agtattaatt
    77641 ataggtatta taagtgtaac agggtttgtt gtatataaaa actgcattaa accatggaaa
    77701 gatgctgaaa catatattga taagtatatg gtaaaacaag atatttcaaa agataatata
    77761 aaaagtatta caaaagaaaa agccaagaag gcaagttacg aaggaatact atacaaagtg
    77821 tattacaaag atgaccctcg atatgagtat caatattttt atagtgataa ttatcatgct
    77881 ctatatgtaa ataaagtaat gttacaaatt tatgatgtgg aaaataataa taaactttta
    77941 agaagtaatg aggaattaaa aagtgtaaag tatccaccaa tatatcttaa atataagcca
    78001 gataaatgat ttatgacaaa atagaatgat ttttattaaa atttatttaa aaatatcact
    78061 agagtgttta aataaaacta aatttaagta tttatatatt agtatatctt aatagcattt
    78121 aaataaaact aaatttgaag ctttacctat taatatatct taatagtgat taaataaaac
    78181 taaacttaag aatttattta ttaacataca gttcattata tttaaaatca ttactatgat
    78241 aattcataat agtaaaatag ataatggttc agacaatatt gtaaatatta gtgacagtaa
    78301 aatagtatca atttagtata taaactttgc cagataatcg cataacagag cttgtagtta
    78361 tagaataaaa aaatatctag gaaaccgttg acagatttat atggatagta taacatatag
    78421 aatatgaaat taaacaaaaa agaattttaa ttatggcgac gtagtcataa ttttgagtat
    78481 gttactgatt agcaggcaga actcaagtat atatgtgaaa aatagaggga tactctatac
    78541 atatatgctt gagttctttt tattgaaagg aggaatatat gaaaataatt cagattttaa
    78601 ataataatgt agccttagta aaaagaggta aaaatgaaat tattgtattt gttaaaggaa
    78661 ttggctttaa aaaaagagtg ggacaagtaa taaatgaaaa tgaaatagag agaacatata
    78721 tactagattc atacgatatg ctagaacact ttagttatct actacaaaac tcagactcca
    78781 ataatatagt tcttattaat gaaataattg aatatggtga gaaagcttta aatataaagt
    78841 caagtgatta tctaagctta accttactag accatttaga gtttttactt aaaagatgtg
    78901 aaaagaatca atttataaaa agtcctttgg tatggaatgt taaaagattt tatccaaagc
    78961 attttgaaat tggaatgcat gcactaaaat taattggtga tagtaaggga attaatcttc
    79021 ctgatgatga ggcagtatca atagcacttc attttgtaaa tatggaggta aataaagagt
    79081 ctcatgatag tacaattgta gagttgagaa ctttagcaga tatagtttct ataataaaat
    79141 atcattttaa tgtagagcta gatgaaactt caacaaatta tatgagattt actactcatc
    79201 tacagtactt tatccaaaga attatgtcag atgaagcttc aatagatgaa gataattcta
    79261 tagatttata taaacaagta agtcaacttt atccaaagtc atttggaagt gttcaaaaga
    79321 taagaaaata tataaaatca caatttaatg tcgatatatc tataagtgaa gaaacttatt
    79381 taatgttgca tataaatagg gtgactcaaa gactggaggc aaaatcagat gaaatataaa
    79441 gatttaaatg aaaatataat aaaacttata gggggaaaag aaaatataaa gtcggtagcg
    79501 cattgtgtta ctcgtttaag acttacttta aatgatagaa gtatcgctca aacagaagaa
    79561 attaaaaaat taaaaggagt aattgatgta gtttctaatg atgttgctta tcaaattata
    79621 ataggtactc atgttgtaga tgtatataac gagtttatgt ctatgatagg tttaagttca
    79681 agtgaatcaa gtataaaaag tgaaagaaaa aagggaatta gaggtatcaa aggtatattt
    79741 aattccatct ttgtggtagt ctcagagact atgacttcag taattgaagt actacttgca
    79801 gctggtatac tcgcaagtat attagcactt ttaaatatgt ctggcatact tcagagtgat
    79861 agccctacat atcaaatatt agatacatta agaagtgcta catttcactt cttaccagta
    79921 ttaattgcaa tagcatcagc aaaaagactt aatgtaaatc cctatatagc agtagtgtta
    79981 gcagttacgt tattatcgtc atcaatagat ggtgtagaag gattaagttt atttggtata
    80041 aatttacagg ctacaactta tgcaaacagt tttattccaa tacttttagg agtatgggca
    80101 atgggaatta taattgaagg tttgaaaaaa atattaccta aagcactaca ctatttttta
    80161 gttccagtgt tatctttaat aataacccta tcagttacat taactgtatt tggacctatt
    80221 ggtatgtgga ttggtgatgg attaaactat gcatgtatgt ttttaattga tacattgggt
    80281 aattggagtg ttgttgcact gtatgcagct ttacaaccac tcttaatagt ttttggtgca
    80341 gcaaacttta ctatgcctat atctttaaat tctgtgacaa cattggggta tgacccaatt
    80401 tttatgggcg ctgcaacaat atctgatatt gcagtttgtg gtgcaatgtt tggatatttc
    80461 ttaaaaacta ggaataaaga acaaaaacaa ttatttggga cagtaagttt tagtgcactt
    80521 atgggagtta cagagccttc agtgtttggt gtgtttatga aatatagaag accatttgta
    80581 gcagtaatga taggtggagg tataggtggt ttaatagcag gtttagctca agttaaaaca
    80641 tatggaatgg tttggggatt agctgcatta ccaacatatc ttgttggagg agaggcatct
    80701 aactttacat ttatgataat aagtgtagta gtatcatttg tagcagcaac agcagcttcc
    80761 tatttactag gaataccttc agatgaaaaa gaagaagtta agggtgataa tgaaaaagaa
    80821 ttagaactaa taatcaacga gaacaattca agaactatta gtattggaaa tgttgcaaaa
    80881 ggtcaggtaa ttgcacttgg ggaagttaat gacaaagcat tttcctctgg agcattaggt
    80941 aaaggggttg gagttatacc tagtgaatca aaatcaactg ttatatctcc tgtagatgga
    81001 actataacta tagtatttcc aactaaacat gcatatggta tagtgactga tgaaggatta
    81061 gaaatattaa ttcatattgg tatagatact gtaaacttag atggaaaatt ctttgaaagt
    81121 cttgtaacac aaaatcaaag ggttaaaaaa ggagatgctt tagcagtatt tgaatctgat
    81181 aaaattatag aggaaggctt tgattctact ataataactg tagttacaaa tactagcgat
    81241 tatttagatg taatctcatc aaatgatgaa tcagaagaat tattaactgt aatagtataa
    81301 attttaggag ggaaaattca tgaatattaa agatacattt ttctggggag gaagtattgc
    81361 agcccatcaa tgtgaaggtt catgggatag tgataacaaa ggacctgcaa ttatggattt
    81421 tgtaactaag ggctcttatg aaacgccaag agtaattact gataaaatag aagaaaaatt
    81481 ggattatcca tctcataatg gaatagattt ttataataga tataaagaag atatagcttt
    81541 atttaaagaa atgggattta gtgcattaag aatatctata gattggtcaa gaatttttcc
    81601 aaatggagat gatgaaaatc ctaatgaatt agggattaaa tactatgaag gtctgataga
    81661 tacattaata gaaaataata tagaacctat tgtaacacta tatcattttg aattacctat
    81721 gaatttagta cataaatatg gttcatggaa taacagaaaa cttatggatt tgtatttaaa
    81781 gtacagtgag actgtaataa gaaggtttga tgataaagta aagtactgga ttacatttaa
    81841 tgagatgaac catattgacc ctcaaacaga gcactcggat atttttactt atatgatagc
    81901 aggtattaag tatagtgaaa tagaaaataa ggttcaaaca ttggcaaatg tagggtataa
    81961 tatgactttg gcgggtgtaa aggttgcaaa gttggctaga gaaatcaatc ccaacaataa
    82021 agttggatgt gtatttggac taaatccaat ttatccatac aattgtaatc ctagtaatgt
    82081 gttaaatgca tttttagata atgatcgtga ttattatcaa attgatgcaa tgtgcaatgg
    82141 gaagtttccc caatataaat taaaagaata tgaaaaaaat aatataacta ttgaagtgac
    82201 tgatgaagac aaaaaagcat ttaaagaagg taagttagat tttataggtc ttaattatta
    82261 tttttcaagt gtatctactc caaaagaaaa tttatcaggt gataaatctt tatttggtgg
    82321 gattcaaaat ccatatttgg aacaaagtaa gtggggatgg gcaatagacc ctataggttt
    82381 aagatttacc ttgaactata tttacagaaa gtatcaatta cctatcttaa ttacagaaaa
    82441 tggtttaggg gcatatgata aaatcgaaga agatggaact ataaatgatg attatagaat
    82501 tgaatattta agtaagcatc tatctcaaat gaagtctgca attgaagagg ataatgttga
    82561 atgttttgga tatttgatgt ggggaccaat tgatttagtc agtgcaacta caggtcagat
    82621 gagtaagaga tatggattta tatatgttga cttagatgat gaaggcaaag gaagttttaa
    82681 gagatataag aaaaaatcat ttgattggta caaagaagta ataaaatcta atggagaagt
    82741 tttagatttt tctacggata tagtagtagg gtagtaataa gataaataga agttaggaac
    82801 taatgttaat tagtgtctag taaagcattt aaaatagagt atagggtctt taaagtaaag
    82861 tgtgtattct tattaaaagt aatggcaact aaaattacta taaaaaggag aatacacatt
    82921 ttttatgttt atacttaagt aaatatttag acatattcat agtataattt actcattata
    82981 taaaaatagt atgatttact cactatataa ctttataaat tttctagaaa aatgtcagaa
    83041 tatattgaca aaaaaaagat ttgaaattat aatctatatt gagaatagtt tgacaatata
    83101 aaaacaagta tttttacaaa tagtgaaatt atttttattg tcaatttaag aataatttag
    83161 gactactata aagatgaagg tatagatgtc attatatgat aaatcatact tgtatagaaa
    83221 gaattttaaa gtatgcttat cattgattta atataataaa taatttttgt ttctagtaat
    83281 agttcatagg aataagatat ctaaattcgc ttagaaatag tctaatttac aaaggagggg
    83341 atgcactagt agataaaatt tttatataaa gaagacttaa agtggagtat attctgataa
    83401 tattggttta atggttatat tattatttcg ttttagatat tttaagaata atttaagacg
    83461 tttgtaaaaa tgtattctat atctaatatt taaataaata taagtcttcc aacatgtata
    83521 ctaagataga aagtagttga agtacaattc taacttgtaa aattatgtag aaagtaaaaa
    83581 tcaaaaagaa atctagtaag ttgataatta tagttaatat ttagagagtt aactctagtt
    83641 atatttattt agatatttta ggaataattt aagacgtata taatatcatc aaaaaatatc
    83701 aagctatacc atatgtagtt aagaataact gcataatata cattttataa ttattgtttt
    83761 attgataaaa aattattata tttaggagga aacaacaatg gaaaattttt ggaatccact
    83821 tacttgcttt actgtatgtg taatgattta tgcttttagt gagtttttat ctaagaaaac
    83881 aaaaggtgca atttcaacat tgttatttgt atgtattata tttttactag gattttggac
    83941 aaatgtttta ccaaaagaca ttacaggagc atcagggata ttagctgcaa tgagcaactt
    84001 tggtatagct ttattaataa ctaacttagg aacacttata aatcttgaag acttatgtca
    84061 tgaatggaaa acggttgtaa ttgcattagt aggtattgta ggaatagggg ttggctgttt
    84121 aacagtgggt agtatgttat ttggtagaga gtatgcttta atagcagcac ctccaatagc
    84181 aggttctact gttgccggta ttatcgtaac aactgttgca gaagctgcaa atagacctga
    84241 acttgctgca tttgtaattc tagtattatc atttcaaaag ttctttggca ttccgataac
    84301 tacatattgt ataaataaag aattaaaatt taaaagagat aacggggatt ttttgaaaga
    84361 tgagtcaaaa agtaatttta gacttccaag tatgagaatt tttaaagaag atttaggtaa
    84421 aaaatcatct actctagtgt atcttgcaaa gctttcattt gttgctatga ttggtaattt
    84481 tgtaggattg gctactttaa taccaggatt tacccctgca aactattatt taaatcctaa
    84541 tatagcatgt ttgttagtag ggttgatttt tacacgaata ggttttttag aaaaaggaat
    84601 tttagataaa tctcaatcta atggaattat aatgtttggt tgtatgttga tgttacctgg
    84661 aggacttgct aaggtaactc caacagcatt gtttgggatg attgttccaa ctataggaat
    84721 acttgttgta ggttctgtat ttataatatt atttactgca attgtaggaa aactattggg
    84781 atattctcca agaatgtcag ctgcaattgg tgtaacttgt atgctagctt atcctgcaac
    84841 acagataatt tccaacgaag gtattgatgc tatggaagga actgaagaag aaaaacaaag
    84901 ggcaacagat tatttattac caaagatgat tataggagga tttgttactg taaccattgc
    84961 atcagtggca tttgctagta taataggtcc aattatattt ggttgatagt aaatatactt
    85021 ataggaggaa taagaaatga taggaagtat atctataaat gagatagata aaaaaagatt
    85081 caaacttgat gatttaagta agaaaatatg ggaaaaccca gaaaaagcat ttaaagaatt
    85141 taaagcatgt gaaaatacag caaactttct aagaagtgaa ggatttgatg tggaagtagg
    85201 tgtaggaggt ttagccacgg ctattagagc tagttttggt tcaggtaaac cagttatagg
    85261 ttttatggga gaatttgatg cattacctgg tttaaatcaa aaagtttcaa caaagcaaga
    85321 agcatttgaa ttgagtgcat atggtcatgg atgtgggcat aatttattat gtacagcaca
    85381 tgtaggggca gtagtaggac ttaaaagaga gatgctagaa aataacttaa gtgggactat
    85441 agtattttat gcatgtccag gagaagaaca attaacaggt aaaggattta tggctagagg
    85501 tggagcattt gaagggttag acttagctat aaattttcat ccaaataaaa ttagtgaagc
    85561 tacaattggt acttcaacag ctgttaactc tgtaaaattt cactttaagg gaaagactgc
    85621 acatgcaggc tcagaccctc aaaatggaag aagtgcacta gatgctgtgg aacttactaa
    85681 tgtgggagct aattatttga gagaacatgt tacttctgat gtaaggattc attatacaat
    85741 tacagatgga ggagtagcac ccaacatagt tcctgataaa gcatcagtat ggtattatac
    85801 aagagcttta agtagagaag ctgtagaaag tacatatgaa agacttgtaa aggtagcaaa
    85861 aggagctgca atgatgactg aaactgaagt tgaagtagag tttttaggag gttgttataa
    85921 tactttaaat aatcatgttt tagcaaatct tgtatcagaa tgtatgaatg agattaaaca
    85981 agagccttgg actcgagagg aattggattt tgcagctgaa ttagatagac aaagcccaca
    86041 acaatataag gctatgataa gtaaatataa tttgccagaa ggaactcatc tatattatgg
    86101 tggaggaaat gttacaaact ttaatagtta tggttctact gatattggag atgtaatgca
    86161 tatagttccg acagcatact tttttacagg gtgtacgaat ctaggtgcac caggtcatag
    86221 ctggcagttt acatcttgtg caggaagttc tataggagaa aaaggtatga tatatgcatc
    86281 aaaaatcatg gctatgtttg gagccaaaat attaaataat ccagagatag ctaaaaaggc
    86341 aaaagaagag tttgataaat ctatgaatgg taaaacatat aaatgtccta ttccagatga
    86401 tattccaact ccttaaaaag acatgaagtt taatatataa aattataatt tttatatcag
    86461 catcatttca ttactaaaag aaagtgagat tttgctgact atctgattag gaggaaggaa
    86521 tatgaaaaat ttttttaaag aagcgcagtc aatagaaggg gaaattatta gatggagaag
    86581 atatttacat gaaaatcccg aaattggttg caatctaccg aaaacagtaa cctttgttac
    86641 cagtacttta gaaaaaatgg gatattctcc gaaattgacg tctaataatg gaatagtagc
    86701 tgttttagac agtgaaaatg gtggaaagac cttattatta agggcagata tggatgcact
    86761 tcctattatg gaggagacgg atttaccttt taaaagtaag aataaagatg catctcatag
    86821 ttgtggacac gataatcaca cagcaatgct cttaggagca gctaaaatac ttatggataa
    86881 taagcactta cttaaaggta gagtaaagtt tgtatttgaa ccagatgaag agagtaccag
    86941 aggtgcaaaa tcaatgattg atgatggtat attagaaaat cctcaggtcg atgcagctat
    87001 ggcatttcac agtatggtgg gtaaatttct taacacaggt caagtagctt attcacgtgg
    87061 tccagctatg gcatctgcgg atatatttga aataacagta gaaggaaaag caactcatgg
    87121 agcaagccct gaatttggag tggacccaat aaacataatg tcgcatatac aaatagcatt
    87181 aaacactata ctttcaagag aaaaacctca gaaagagcct gtagttttaa ctattggtat
    87241 gtttaatgca ggaaacgtac caaatgctat accaaataaa gcatctatgt caggaacttt
    87301 aagaacattt gaccaatttg ttagagaaaa attaaaaaat agaattattg aaatatctac
    87361 aggaatagct aaatcatttg gaggaaatgc taaagtggaa tttaaaatgg ggactcccgc
    87421 agttataaat gatttggatg taggagatga gattgtatct tatgttaaag aaattatagg
    87481 aaatgagaat gtaatagact ttccatctgc aatgggttca gaagattttt cagagatttt
    87541 actaagggtt ccaggagtat ttttatggat tggaatggga agtattagtc agggatataa
    87601 ttttggtatg cataatccta aagcaatttt taatgaagag ggattagttt atggttcagc
    87661 tttatttgct cattgtgcag taaaatggtt agaaaataat tttagtagat aataacataa
    87721 aatattatta aatatcataa aaggtatatc ttaaaaagat gcaaagatat accttttaga
    87781 aagtcatata taattttact taatattaga tgataaaata tttttatgca ttttggattt
    87841 taatatttat tttctgatat aaataatttg tatacccttt caggtctacc ttttgttgag
    87901 ttttgttttt catataatat agtagcgttt ccagacttta agagactact tagaaatcta
    87961 ttagcagttc taactgttac atttaaacat gaagataatt ccttaggagt aacttcatct
    88021 ctttgtagaa tttcagtaac agatataatc ttttgaatag taagagtaga caatttagaa
    88081 cttttggcaa ttgtatttat atgtggagtt actttatttg aaacagtaag taacttatca
    88141 cacagtaaag gtcctattgt ctcataattt tcgttgacta agaaactgta atttaaagga
    88201 tttattttag attccttatt agcacttatg gcactagaca tagcttgctt tatatcatta
    88261 ccaattccat atccaacaca tactttaata tttgtactat tttcaataga ttcttttata
    88321 taacatgcag taaaattttt agttaatgat ttaatcgttt cacatttagt gaaaatttta
    88381 aaagaattac tatttttttc aattataaaa tcggttaatt tatctttttt aatactattt
    88441 aatattttat aaacttggtc tagagtagag tcatcataat ttgtatcttt aactgttata
    88501 tatattacac ttggttgatt tcccttcatt ctatgtaaat gaatatcttt tattaagtta
    88561 ttaaaagtat tttttaataa atctatatca gggtatatga aatgaaagtt tactcctgca
    88621 ttttgtaaca taggaacaat actactaaaa cgagtagtag aaaaatcgat tttcccttca
    88681 ttccatagat taatatgttt ttttgcaatc tttttttcaa gttttgctat gtcagataaa
    88741 ctcattttag atgcattttc atcaatacta tccattaagt ctccaaatgt gccatttgat
    88801 aaataatatg atatatcttt tggattatct gcccagtctg ttaagtcaaa gtatgctcta
    88861 gaaaaatcta atgtattata tttaaagata agctttagaa acatatcata gtaactttgt
    88921 aagtcagtac caaactgaac ctcccatgac taaagtcaca gggttcctgc ttcatagaat
    88981 tttgcatact aaaatatgtc ttactaattc ttcacaggcc atccccgtag ttcctacggt
    89041 tcttacataa gttatttatt ttgaattgtt attagtctta atccttcttt taatatattt
    89101 atacttgcat ttatatctct atcgtgagtt tcattacaac taggacaaat ccattctctt
    89161 atatttaagt ccttcacttc ctcgttttta tacccacatt tattgcatat ttgtgaactt
    89221 gcaaagaatt tacctacttt tacaattttt ctaccatgcc aattagcctt gtattctaat
    89281 tgacgaataa actctgacca tgatacatca gaaattaagc gagatagtct acgattttta
    89341 atcatattct ttacttgtaa atcttctatg caaataatat cattctcttt tattaattta
    89401 gtagataatt tttgtagaaa atcatttctt tgattagcta tatgttcttg aagtct
//
LOCUS       DAMJWO010000005        86204 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.006, whole genome shotgun sequence.
ACCESSION   DAMJWO010000005 DAMJWO010000000
VERSION     DAMJWO010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 86204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 86204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..86204
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.006"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            110..301
                     /locus_tag="PC366_000381"
     CDS             110..301
                     /locus_tag="PC366_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HDF2575936.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            456..1865
                     /locus_tag="PC366_000382"
     CDS             456..1865
                     /locus_tag="PC366_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2575937.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKKGQVYKKLGYKDILKNLYKM
                     DTTEILGTDNLHFPEGIIKNSQKKASRVFKSDYTCYLVNGSSCGIQSAIMSVCSPKSK
                     IITNRDCHQSVINGCILGDIDIEYVPCEISEETNVLKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPAFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGK
                     ELMEELLNNIRIFKDKVDSNINIYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTAEDFSSLETALNNVVKEDFKFEKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKICGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVDLNFIQVIDLEDI"
     gene            1996..2685
                     /locus_tag="PC366_000383"
     CDS             1996..2685
                     /locus_tag="PC366_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HDF2575938.1"
                     /translation="MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIIIADRY
                     TTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPQPDCVIFLDVPIEFSKKLMENRK
                     NKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKPMER"
     gene            2688..3623
                     /locus_tag="PC366_000384"
     CDS             2688..3623
                     /locus_tag="PC366_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HDF2575939.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEK
                     MTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLI
                     NTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIP
                     NNMEKYRGKIIALLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMSGKISYSQLS
                     KIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3620..4513
                     /locus_tag="PC366_000385"
     CDS             3620..4513
                     /locus_tag="PC366_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HDF2575940.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4591..5337
                     /locus_tag="PC366_000386"
     CDS             4591..5337
                     /locus_tag="PC366_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HDF2575941.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSIKLNGLEERVEIINED
                     IKYIDKVLDINGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRASSRLVM
                     PRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNKDIGEL"
     gene            5338..6171
                     /gene="rsmI"
                     /locus_tag="PC366_000387"
     CDS             5338..6171
                     /gene="rsmI"
                     /locus_tag="PC366_000387"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HDF2575942.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRTLKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHRFVFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMLKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEVRGEFVL
                     IVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6194..6898
                     /locus_tag="PC366_000388"
     CDS             6194..6898
                     /locus_tag="PC366_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HDF2575943.1"
                     /translation="MEIGKIIIESLKREDTHKIFIELDNKHELEKIIPKISCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNDKDFFPIHLRKHVSNYLNTYIEEGINKLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGIKLELSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7086..7514)
                     /locus_tag="PC366_000389"
     CDS             complement(7086..7514)
                     /locus_tag="PC366_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HDF2575944.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7551..8981)
                     /locus_tag="PC366_000390"
     CDS             complement(7551..8981)
                     /locus_tag="PC366_000390"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HDF2575945.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9113..9697
                     /locus_tag="PC366_000391"
     CDS             9113..9697
                     /locus_tag="PC366_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein A"
                     /protein_id="HDF2575946.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTAVAIITCKFFQRRYR"
     gene            9713..10234
                     /locus_tag="PC366_000392"
     CDS             9713..10234
                     /locus_tag="PC366_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein"
                     /protein_id="HDF2575947.1"
                     /translation="MEIFSNLLIPIIILYIVVYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10300..10546
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10630..12567
                     /gene="metG"
                     /locus_tag="PC366_000393"
     CDS             10630..12567
                     /gene="metG"
                     /locus_tag="PC366_000393"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HDF2575948.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTDFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDETKKDELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKIISCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12597..13367
                     /locus_tag="PC366_000394"
     CDS             12597..13367
                     /locus_tag="PC366_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HDF2575949.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIETSI
                     TAIELAKKYDFIYSAVGVHPHDVSKLDDTAIETLRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKNPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGICYEEVCRVTKENAKKFFNIK"
     gene            13704..14135
                     /gene="phnG"
                     /locus_tag="PC366_000395"
     CDS             13704..14135
                     /gene="phnG"
                     /locus_tag="PC366_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HDF2575950.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMIKDTSSISIIKEPNLATVMV
                     RANESVKNTTFNLGEILVTECSVKVDESLGYGIVSENNNKKAIYLAVIDAVLHSNNSK
                     FDELKNYINKSVYEENLRYEQEIIDEFSLINKTKVQFNAMD"
     gene            14150..14725
                     /gene="phnH"
                     /locus_tag="PC366_000396"
     CDS             14150..14725
                     /gene="phnH"
                     /locus_tag="PC366_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HDF2575951.1"
                     /translation="MVNYTQEIYRKMLDSASFPGKLNNIDNINIENNTKLLNGAIGIA
                     ITLLDQEVTFYIENYTQKDIKNIRALTVSNQIDYRKSDYIFLDINSEVDILQIKIGSF
                     EYPDESATIVHQVNDLSTYSQTKYIKLDLSGPGIKSKNSIYINGIREEFIERLSTINK
                     DYPIGIDLILVDKKGEIAFIPRSSKLSWEVL"
     gene            14728..15813
                     /locus_tag="PC366_000397"
     CDS             14728..15813
                     /locus_tag="PC366_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit PhnI"
                     /protein_id="HDF2575952.1"
                     /translation="MAYVAVKGGEEAILQAKNILEFYRVKGDSLPIDVKQIEEQMSYA
                     VDKVMSEGSLYNKELSALAIKQAQGDILEASFYVRALRSTMPRITYSEPINTEEMRIK
                     RRISATFKDIPGGQYLGATRDYENRILNVELLEEDEKKNRDFRDSFINELETVDEIPE
                     FTKISNIFRKENLLQEEVCENKLEEVIDDITRNSLRFPVSRSAKLQALTRGESGVVSG
                     FAYAIVRGFGDEHPYISELRTGNVFIKVKHPIYEDEEIIIGDMLVTECEIVSKASQNK
                     TENSKTNSEDKNKMSLGYGLCMGNNENKAISMAILDKSLEPNSEKLAQDEEFVLLHID
                     GIDSLGFISHFKLPHYVDFKADVERIK"
     gene            15833..16702
                     /locus_tag="PC366_000398"
     CDS             15833..16702
                     /locus_tag="PC366_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HDF2575953.1"
                     /translation="MIYNYGFLDENTKKEIRRKILKAISIPGYQVPFGSRELPIAKGW
                     GTGGLQLTLSLIGKNDVVKVIDQGSDDSTNACNIRSFIASVSNVETTKDTLEATLIQT
                     RHRIPEEKLKSNQILIFQVPIPETLRIVEPSEVETRRMHSEEDYSRMWVYLYEDIVRF
                     NDISIAVEYPCKVNDRYLMNPSPIPRFDIKKLNMSDNLFLFGAGREKRIYAIPPYTKV
                     EPLEFEDYKFEEEKFEGKYCSLCNSTNTFLDEVYDSDTNEKYYSCSDTSYCEKVRLKN
                     NSIDVTIGGTWNE"
     gene            16695..17561
                     /locus_tag="PC366_000399"
     CDS             16695..17561
                     /locus_tag="PC366_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2575954.1"
                     /translation="MSKINVSKRLENIDKQVLIGRNINLIYGDGCEKCFESTGYESNN
                     ICKYCGSIVACNNVNLELYEGEVLGIVGESGSGKSTLLKILFFQEHANSGEVYISHYN
                     KDTNILELSDQKKRYIKNHFMGIVYQNPHLGLNLDFSSGGNIAEKLLMANLYNVEKIR
                     DRGKELLIKTNIPVERIDHKPKYFSGGMQQRVQIAKALSNNPPILLLDEVTTGLDVSV
                     QAEVLDLIREIQRELKISMIVVSHDFDVIKMLADRTIVMKNGSVIESGLTDQIMEDPQ
                     HPYTQQLINSLL"
     gene            17602..18315
                     /locus_tag="PC366_000400"
     CDS             17602..18315
                     /locus_tag="PC366_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2575955.1"
                     /translation="MKETILEVNNFSKDFELHALNKTITACSNISFEVSKGEFLGIIG
                     KSGAGKSTILKSIYKTYIPTTGEIIFNSEIYGNVDLAKIGDREMINLRKKEIGYVSQF
                     LKTLPRITAIELVVHSLIESGFEKDCSYDMAKDILNQFEIKENLWDAYPNNFSGGEKL
                     RLNLAQAMVKKPRLLLLDEPTASLDNQSKIYVKEKMLELKSQGTTMIGIFHDIEFMET
                     VIDKTFTMAKGTISESGVA"
     gene            18316..19485
                     /locus_tag="PC366_000401"
     CDS             18316..19485
                     /locus_tag="PC366_000401"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HDF2575956.1"
                     /translation="MIKLIHNANIVLEDMILENGHLIIEGDTIKKVSNDRIDYAFDFN
                     EIDEIIDAKNLYVIPGIIDIHSDAIEKEIEPRPSTLLPFNMAFYELDKKLPANGITTV
                     YHSISLGDGVGVRSIDNSLKMIKNIDSYKNIDSKSINHKVHLRYEVLYYEGLEKVLEL
                     LDENKIDYLSIMDHSPGQGQYTNPTFYKEYATKVWGVTENYVDTWLDDLVNLHDNLDW
                     NKIANIIGIAKTKNINVASHDDDTLEKMDFIKNIGINVSEFPITLEVAKHSKKLGVLT
                     CLGAPNIVRGKSHNNNLKAMDAILEDCCDIVCSDYLPSAMIKSMCIVAERINNLNKAV
                     SLFTSNPAKAVGIYDERGSIKENKKADLVLVDIDSEYPKVLNTIVNGKTVYKREV"
     gene            19489..20325
                     /locus_tag="PC366_000402"
     CDS             19489..20325
                     /locus_tag="PC366_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HDF2575957.1"
                     /translation="MLTELHCHTSISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEALVLGEHYGITIIPGIEISAYDYKNRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSSLYKELFH
                     RGNGKVYVSLKYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            20326..21321
                     /locus_tag="PC366_000403"
     CDS             20326..21321
                     /locus_tag="PC366_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2575958.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKEVLDVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDDGINKIAIRPEDIKVESNRDSKDKDIKVGEILDIE
                     FRGFNYRITVEYRSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            21339..23027
                     /locus_tag="PC366_000404"
     CDS             21339..23027
                     /locus_tag="PC366_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HDF2575959.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLVSLLKNAFM
                     DTSGNFIGISNFSKYVENPSLIASFKNSIFVSTVSSLISLCLAFIYSYAITRTNIKFK
                     DFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIVCSFITLLIFILIFVSVIGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAIFGTIFVFFSAYIIEKVDKFPKLRQTAYLLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNVVHFYSVCFITSNSSLKMLDK
                     EYELVAKSINIPFYKVFFNITVPMSITSILEIVVYYFVNSMVTVSALIFLYIPQTQTA
                     SISILKLDEIGYIGPSAAMAVLVLLTNIIVRLLYEFVTKKLKNNTQKWQQKDVA"
     gene            23039..24106
                     /locus_tag="PC366_000405"
     CDS             23039..24106
                     /locus_tag="PC366_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2575960.1"
                     /translation="MKFKKLVSLGVLSTLLLSVITGCSTDSSGSDSKSDSKTKGDLTV
                     YTAIEEDSIEPYLATFKEKYPDIKLNIVRASTGDITARLLAEKDNPQADVVWGVAATS
                     LLVADDQGMLEPYAPKGSEEIESAFKDDKEVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPSSSGTGYLTVSALIQIMGEEKAWQYMDKLHENIGVYT
                     QSGSAPATSAASGEYPIGISFGYRGIKLKEEGYPVEVVFPKEGSGWDIEANALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNYAVTTISTGNPIPEGFPKKPLEQMIDNDLKSAAK
                     NREDILNKWISKYDGKTEKES"
     gene            24592..24708
                     /locus_tag="PC366_000406"
     CDS             24592..24708
                     /locus_tag="PC366_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter ATP-binding protein"
                     /protein_id="HDF2575961.1"
                     /translation="MDDDINMIAIRPEDIRVEFNRDFKEIIDLKLRPYRYKN"
     gene            24872..25939
                     /locus_tag="PC366_000407"
     CDS             24872..25939
                     /locus_tag="PC366_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2575962.1"
                     /translation="MKFKKLVSLGILSTLLLSVITGCSNVSSGSNLKSNNKTKGELTV
                     YTAIEEDSIDTYLATFKEKYPDIKLNVLRLSVGGITARLLAEKDNPKADVLWGVAATS
                     LIILDDKEMLEPYAPKGFDKVNPAFKDDKKVPSWVGIDAWMTGITVNTKELKAKNISA
                     PNSYEDLIKPEYKDLISMPSPASSGTGYLTVSELIQIMGEEKAWQYMDKLHKNIGVYT
                     QSGSAPAILAASGEYPIGISFGNRGIKLKGEGYPVEVVFPKEGSGWEIESNALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNFAVTTIDTGNPVPEGFPKNPLEQMIDNDLKSAAR
                     NREAILNKWIEKYDGKTEKES"
     gene            26131..26661
                     /gene="rnmV"
                     /locus_tag="PC366_000408"
     CDS             26131..26661
                     /gene="rnmV"
                     /locus_tag="PC366_000408"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HDF2575963.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMQRIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRDEFKQVDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREEFIDALKQI"
     gene            26832..27701
                     /gene="rsmA"
                     /locus_tag="PC366_000409"
     CDS             26832..27701
                     /gene="rsmA"
                     /locus_tag="PC366_000409"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HDF2575964.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITRGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLDNTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EDIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREILKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            27767..29038
                     /locus_tag="PC366_000410"
     CDS             27767..29038
                     /locus_tag="PC366_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575965.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDSDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEEYEEYEELEEDEEIEDNEESDRDEDS
                     EEEYIIEEYDEDEYEDYWEDDEDIEEGELKARTEVEDSGDEEIEEFNNYKEIENYNRV
                     KVQEEYIDIEYDEEEEEEEEVFEVNREEDRFVSSKPTKSKKVQKDQNNIEKIKRANGV
                     SQGESGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTMP
                     YLGYLNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGST
                     GFLRYQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            29189..30304
                     /locus_tag="PC366_000411"
     CDS             29189..30304
                     /locus_tag="PC366_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2575966.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVI
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEANGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIVAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            30490..31386
                     /locus_tag="PC366_000412"
     CDS             30490..31386
                     /locus_tag="PC366_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF2575967.1"
                     /translation="METRYEEANKITIQSILWNVVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASIVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDENLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            31456..32253
                     /locus_tag="PC366_000413"
     CDS             31456..32253
                     /locus_tag="PC366_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575968.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITHGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(32309..33661)
                     /locus_tag="PC366_000414"
     CDS             complement(32309..33661)
                     /locus_tag="PC366_000414"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HDF2575969.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYEGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            33880..34758
                     /gene="purR"
                     /locus_tag="PC366_000415"
     CDS             33880..34758
                     /gene="purR"
                     /locus_tag="PC366_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HDF2575970.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDLIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            34914..35192
                     /gene="spoVG"
                     /locus_tag="PC366_000416"
     CDS             34914..35192
                     /gene="spoVG"
                     /locus_tag="PC366_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HDF2575971.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            35402..36781
                     /gene="glmU"
                     /locus_tag="PC366_000417"
     CDS             35402..36781
                     /gene="glmU"
                     /locus_tag="PC366_000417"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HDF2575972.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEAEVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVMIGNDTIIYPG
                     VMLQGKTRIGSDCIIGMNSSITNSEIGDGTEIKNSTIIDSKVGENSNVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SVVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHDVPDGALAIARERQVIKEGWVEK
                     KNQKDDQSK"
     gene            36876..37826
                     /locus_tag="PC366_000418"
     CDS             36876..37826
                     /locus_tag="PC366_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HDF2575973.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      38666..38751
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            38913..39434
                     /locus_tag="PC366_000419"
     CDS             38913..39434
                     /locus_tag="PC366_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2575974.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSVKSAALSYYSDTNKIPVTPDGQTGLSVLETYMESLPDKADIGGKYKLIKVG
                     NKLVLQIGTNDEGVTLTEAQSAKLLSDIGENKIYTSVTADNLGNPLTSNTKVDNKVLY
                     IVLIDNTVMDSTK"
     gene            39585..41261
                     /locus_tag="PC366_000420"
     CDS             39585..41261
                     /locus_tag="PC366_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HDF2575975.1"
                     /translation="MAKKVRIGDKLVEKGYITEDQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            41273..42481
                     /locus_tag="PC366_000421"
     CDS             41273..42481
                     /locus_tag="PC366_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HDF2575976.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTTFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTSVGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILASAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISRQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            42496..44208
                     /locus_tag="PC366_000422"
     CDS             42496..44208
                     /locus_tag="PC366_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HDF2575977.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHDKDKFYVKNFNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETHDNSDGDESSLNLIIGAIQKEEVNAIVEIMHEFDLVLDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQIKAKQMKNILK
                     IAPIVILILAIPYLCLIFSNNLANKELENVNGEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGTNNKADNSKSNKTTTDK
                     SSNNETKSSTKSDSNGDKTDNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSNYTFSMTLYLKEGV
                     LTNE"
     gene            44201..45109
                     /gene="pilO"
                     /locus_tag="PC366_000423"
     CDS             44201..45109
                     /gene="pilO"
                     /locus_tag="PC366_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HDF2575978.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGILIKVIILLAILSYGYFGLYPQ
                     YQKYIATKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVKEYEHFYGISTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEILKNDKLLDRSTNYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            45136..45702
                     /locus_tag="PC366_000424"
     CDS             45136..45702
                     /locus_tag="PC366_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2575979.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGNNYEYNIEMPDNVVKYEVSIETKKN
                     TEVYSVTRIQNNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTGKSIYTVSIY
                     YNESVQESHKNSNLNNKTYTFDVMSRIG"
     gene            45739..46266
                     /locus_tag="PC366_000425"
     CDS             45739..46266
                     /locus_tag="PC366_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2575980.1"
                     /translation="MSKKNSERGFSLIEVLVAMAIMGIVLFAFFNIINTNNKANTKND
                     TDITSLNYVQSEIENLREKIKSGEFDFDSLDKLEDGTVVYEKLIDKSKKVVYDKVLSE
                     GDVSLYDTPYEKITTIKDEDGNLIDKGNITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            46287..47825
                     /locus_tag="PC366_000426"
     CDS             46287..47825
                     /locus_tag="PC366_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575981.1"
                     /translation="MRKWNKFKSERGAALVLVLIVVALLSIVGLIFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQEKSISRSKLRNISDE
                     DFNNQDEKNIEAERLGYMNNINFYLNKASSDLEKASMELKKLYDLDMLDYRDIEYVDA
                     NIISHRDSILEICKNYTSGDISKINEYILKEDIDSTTLIEAKLVNNDILLKMFLEENK
                     IENEHLNSAFSHTYKALDNISLAMQNMIEYRHTFHIDEPKVEVSNGIPDSQQYYELIQ
                     NPIINSMEYIWNSKWDTLENLLEILPNQTQGFNSLRVHLRNNVRKFEKLSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEIDKTEGITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKDGIKE
                     VEVTDGKKNIIGLGVEENSNSKYKVDAIVNFNLNIDTNVVGNYDIKDKILINHDISSY
                     KKVN"
     gene            47925..49007
                     /locus_tag="PC366_000427"
     CDS             47925..49007
                     /locus_tag="PC366_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HDF2575982.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTS
                     EVTMQMAKDIAGESIFKVIEEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPESIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKVGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            48988..49770
                     /locus_tag="PC366_000428"
     CDS             48988..49770
                     /locus_tag="PC366_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDF2575983.1"
                     /translation="MDIIIVNLYVFIVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLMSGRKCRYCYEKISSRYAIVELITGILFLTVFMLYGISTSTI
                     YYLVLVSLLIIITFIDIDHFIIPDKILIFGAIFSMIFNLLFKEIPVKDSILGVFICGG
                     SVWIIVLLIEFVIKKECMGGGDIKLFAMLGLYMGVKNGLLTALLSVYVGAVYGICVII
                     ISRIKGKEYNSVIPYGPFISIGALITILCGKQLLELYFSMVI"
     gene            49872..50522
                     /locus_tag="PC366_000429"
     CDS             49872..50522
                     /locus_tag="PC366_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDF2575984.1"
                     /translation="MEYIIIISLFFAHLINKSLCVFCDREKKNLYNTFFIYIITVVLS
                     VLIYLKFGISVECVQYMVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLAFFNI
                     AQFDYINHIFGLLIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFI
                     LAFLFFIILYITKIFKDVDIRKQIPFTPFISLSTILIIFTEYNIFNFYYNLLYKFI"
     gene            50536..51096
                     /locus_tag="PC366_000430"
     CDS             50536..51096
                     /locus_tag="PC366_000430"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDF2575985.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINE
                     ALEKAADAIDSIIRENIDMSMNKYNG"
     gene            51113..54499
                     /gene="mfd"
                     /locus_tag="PC366_000431"
     CDS             51113..54499
                     /gene="mfd"
                     /locus_tag="PC366_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HDF2575986.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYMEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDSLDLEKLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGAENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTSNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            54530..55525
                     /locus_tag="PC366_000432"
     CDS             54530..55525
                     /locus_tag="PC366_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2575987.1"
                     /translation="MKKVITLVIAMILVVSVTACSSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFAKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSDKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDTSASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            55649..56188
                     /gene="spoVT"
                     /locus_tag="PC366_000433"
     CDS             55649..56188
                     /gene="spoVT"
                     /locus_tag="PC366_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HDF2575988.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            56308..57921
                     /locus_tag="PC366_000434"
     CDS             56308..57921
                     /locus_tag="PC366_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDF2575989.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNVMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLVFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICVGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            58028..59476
                     /gene="mazG"
                     /locus_tag="PC366_000435"
     CDS             58028..59476
                     /gene="mazG"
                     /locus_tag="PC366_000435"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HDF2575990.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLINSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEILPSMSFVDAMFNYLAIDPSEGFKLVDAFEIENSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEHYDYNQEVCIVNGAGVKDLESKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     DFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            59565..59843
                     /locus_tag="PC366_000436"
     CDS             59565..59843
                     /locus_tag="PC366_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HDF2575991.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            59915..60157
                     /locus_tag="PC366_000437"
     CDS             59915..60157
                     /locus_tag="PC366_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HDF2575992.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYEILE"
     gene            60219..60473
                     /locus_tag="PC366_000438"
     CDS             60219..60473
                     /locus_tag="PC366_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YabP"
                     /protein_id="HDF2575993.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            60474..61007
                     /locus_tag="PC366_000439"
     CDS             60474..61007
                     /locus_tag="PC366_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2575994.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKLKN
                     KKKSKPKKKKNKTKKRV"
     gene            61013..61297
                     /locus_tag="PC366_000440"
     CDS             61013..61297
                     /locus_tag="PC366_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HDF2575995.1"
                     /translation="MNLRKKFSGQIIVISLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINSLKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            61410..62330
                     /locus_tag="PC366_000441"
     CDS             61410..62330
                     /locus_tag="PC366_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HDF2575996.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSDKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQGDDTIIVIDIGGGSTEFIVGDSEGIKFNKSENVGAL
                     RMTERFLKHDIIEDEEFEAMSSFIYDEIDKTLNHIKDRGLKTLIGIGGTITSLSAMNQ
                     ELEIYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            62420..64792
                     /gene="spoIIE"
                     /locus_tag="PC366_000442"
     CDS             62420..64792
                     /gene="spoIIE"
                     /locus_tag="PC366_000442"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HDF2575997.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISMGQAFFSNRYVYGLLIAGVEAIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAVYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNNEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            65143..67035
                     /gene="pepF"
                     /locus_tag="PC366_000443"
     CDS             65143..67035
                     /gene="pepF"
                     /locus_tag="PC366_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDF2575998.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNNDRAIAVMNNN
                     DTEDDAEKKQEVDYEKTCWNLQSLFKSDDQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMSDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESVDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLESDNVDEKVYNNLIRTVNSNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            67149..68114
                     /gene="galU"
                     /locus_tag="PC366_000444"
     CDS             67149..68114
                     /gene="galU"
                     /locus_tag="PC366_000444"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDF2575999.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNEARELEIQK"
     gene            68614..70218
                     /gene="rho"
                     /locus_tag="PC366_000445"
     CDS             68614..70218
                     /gene="rho"
                     /locus_tag="PC366_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HDF2576000.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKVNEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQENRNQRNDYNKTTSVNDSNKSSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            70371..70571
                     /gene="rpmE"
                     /locus_tag="PC366_000446"
     CDS             70371..70571
                     /gene="rpmE"
                     /locus_tag="PC366_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HDF2576001.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            70716..71609
                     /locus_tag="PC366_000447"
     CDS             70716..71609
                     /locus_tag="PC366_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HDF2576002.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            71627..72475
                     /gene="prmC"
                     /locus_tag="PC366_000448"
     CDS             71627..72475
                     /gene="prmC"
                     /locus_tag="PC366_000448"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDF2576003.1"
                     /translation="MTIKDIIIKYSDKLKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTKFMGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISETALEIAKKNAIINEV
                     GEKIKYINSDLFTAISDSNIKFDIIVSNPPYIKKQDIETLHKQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKCGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            72519..73583
                     /gene="prfA"
                     /locus_tag="PC366_000449"
     CDS             72519..73583
                     /gene="prfA"
                     /locus_tag="PC366_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HDF2576004.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            73712..74392
                     /locus_tag="PC366_000450"
     CDS             73712..74392
                     /locus_tag="PC366_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HDF2576005.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGLSGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDVSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            74421..75461
                     /locus_tag="PC366_000451"
     CDS             74421..75461
                     /locus_tag="PC366_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HDF2576006.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNVIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVATKINDMIKSNRDKGLKTGVMC
                     ISRNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKGVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            75478..75927
                     /locus_tag="PC366_000452"
     CDS             75478..75927
                     /locus_tag="PC366_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HDF2576007.1"
                     /translation="MNILIVCTGNTCRSPMAEAILRKAIKESGRSIEEYSISSAGIST
                     ANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILVQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVKKI"
     gene            75944..76396
                     /gene="rpiB"
                     /locus_tag="PC366_000453"
     CDS             75944..76396
                     /gene="rpiB"
                     /locus_tag="PC366_000453"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HDF2576008.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLESKGIECVDYGTNNATDSVDYP
                     VYGEIVANSVINKEVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNDA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            76432..77061
                     /gene="upp"
                     /locus_tag="PC366_000454"
     CDS             76432..77061
                     /gene="upp"
                     /locus_tag="PC366_000454"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HDF2576009.1"
                     /translation="MSKVVETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            77361..78176
                     /locus_tag="PC366_000455"
     CDS             77361..78176
                     /locus_tag="PC366_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HDF2576010.1"
                     /translation="MKNCIAVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEGVECIFCNTEKEIEEVLSQHKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPLTIALGPGFCAGEDVDVVIETMRGHNLGRIITNGRAEKNTGVPG
                     AIKGFSKERVMHSQYDGIMENVCKIGDIVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGAKVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            78402..78839
                     /locus_tag="PC366_000456"
     CDS             78402..78839
                     /locus_tag="PC366_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HDF2576011.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            79024..79251
                     /locus_tag="PC366_000457"
     CDS             79024..79251
                     /locus_tag="PC366_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HDF2576012.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            79256..79642
                     /locus_tag="PC366_000458"
     CDS             79256..79642
                     /locus_tag="PC366_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HDF2576013.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAIRLFIMAVVLIASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            79645..80349
                     /gene="atpB"
                     /locus_tag="PC366_000459"
     CDS             79645..80349
                     /gene="atpB"
                     /locus_tag="PC366_000459"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HDF2576014.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGEILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            80418..80678
                     /gene="atpE"
                     /locus_tag="PC366_000460"
     CDS             80418..80678
                     /gene="atpE"
                     /locus_tag="PC366_000460"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HDF2576015.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            80801..81298
                     /gene="atpF"
                     /locus_tag="PC366_000461"
     CDS             80801..81298
                     /gene="atpF"
                     /locus_tag="PC366_000461"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HDF2576016.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKSDLAEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQERQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            81295..81840
                     /locus_tag="PC366_000462"
     CDS             81295..81840
                     /locus_tag="PC366_000462"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HDF2576017.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIDGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            81857..83359
                     /locus_tag="PC366_000463"
     CDS             81857..83359
                     /locus_tag="PC366_000463"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003405060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HDF2576018.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            83387..84265
                     /gene="atpG"
                     /locus_tag="PC366_000464"
     CDS             83387..84265
                     /gene="atpG"
                     /locus_tag="PC366_000464"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HDF2576019.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIAKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMAVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            84278..85672
                     /gene="atpD"
                     /locus_tag="PC366_000465"
     CDS             84278..85672
                     /gene="atpD"
                     /locus_tag="PC366_000465"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HDF2576020.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVRKAKGSM"
     gene            85675..85935
                     /gene="atpC"
                     /locus_tag="PC366_000466"
     CDS             85675..85935
                     /gene="atpC"
                     /locus_tag="PC366_000466"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HDF2576021.1"
                     /translation="MASEFSLKVVTPSNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFINVTQDKTVILTESAEWI"
BASE COUNT        34746 a         9292 c        15833 g        26333 t
ORIGIN      
        1 attttttgtc aaaaaaaaca aaaaatacgt atttattttt tcatttcggg aaaactaaac
       61 acaggaatta tggactttat aaaaatttaa ttcttgagga gtgatataag tgaaaaaagt
      121 tgctttaatt ttagctataa taggtgcgct taactggggt gcaattggta ttctaggtac
      181 agacttaata ggtagtatct ttggtggaac atatgaaatg gtaagtagaa taatatactt
      241 cattgtaggt ttagctggat tatacttaat accaagttta atgtctgatg atagagaata
      301 atttatgctt ttatgttaaa tacctcattc taaatgttta gaatgaggta tttaatttta
      361 taaaaatatt aatttgtttc ttttttaatg gtaaaataga taagaattga agttttaaaa
      421 agaagtatta tgtaaaaaag gagtactatt aatatatgtt tattattaat gaattaaata
      481 agattgtaaa tgaagaagta atatcttttc atatgcctgg tcataaaaag ggacaggttt
      541 ataaaaagtt aggatataaa gatatactaa aaaatttgta taaaatggat acaactgaga
      601 tattaggaac agataattta cactttccgg aaggaattat aaaaaattca caaaaaaaag
      661 catcaagagt atttaaaagt gattatactt gctatttagt aaatggtagt agctgtggaa
      721 tacaatctgc aataatgtca gtatgtagtc ctaaaagtaa aataataaca aatagagact
      781 gtcatcagtc tgttataaat ggatgtattt taggagatat agatatagag tatgtgcctt
      841 gtgagataag tgaagagaca aatgtcttaa aagggatatc tataagtaat gtgattgata
      901 taatagataa aaacttggat gcaaaagcag tactgcttac ttatcctaca tattatggaa
      961 tgacatatga tttagaatac atatgtaatt atgcacatag caaaaagatg gtagtgatag
     1021 tagatgaagc acatggtgcg catttagggc ttagtgagag gcttcctaaa acagctcttg
     1081 agcaaggtgc agatatagtt gtacagagta cacataaaac tcttccagca tttacacaat
     1141 cgtcaatgat acatatacag ggagaccgag ttgatataga taaaatattg aacatgttaa
     1201 gaattacaga atcttcaagc ccttcatatt tattattatc ttctctggaa ttagcagtag
     1261 atatatatga aaataaagga aaagaattaa tggaagagct tttaaataat attagaattt
     1321 tcaaagataa agttgattca aatattaata tatatgacac aaatgataaa acaaaaatat
     1381 ttatatcatc taaaaacatg ggtttaacag gttatgaact agaaaatatt ttgagaaaca
     1441 aatataacat acaagtggag ttatctaatt attatggagt tcttttaata tgtacaatag
     1501 gaaatactgc tgaggatttc tctagtttag aaacagcatt aaacaatgtt gtaaaggaag
     1561 actttaaatt tgaaaagtta gaaaataaaa aataccctgt tgttattcca aagaaaatat
     1621 taacacctag agaagcattt tataaaacta aaaaaagtgt taaaatatat gacagcatag
     1681 gtaaaatttg tggtgaatgt atagttccat acccacctgg aataagtgta atatctcctg
     1741 gtgaagtaat aagtaaagaa ataatagact atctaatgtt ttgtcattct aaaggcatga
     1801 ttgtgagtgg attgaaagat gtagatttaa attttataca agtaatagat ttagaagaca
     1861 tttaaaaatt atgatataaa agtagataga agtagatagt ttaaaattgt gaagagaaat
     1921 aaatagactg cttatataga gctatctaat aaaagtacta aaaaagtaaa aagtgtttgt
     1981 atggaggata tgaaaatgaa aggtaagtta ataattatag agagtggttc agatgcaagt
     2041 ggaaaggcta ctcagacaga aatattatat gaaagattaa aaaaagaagg ctatatgatt
     2101 aaaaaggtag aatatccaaa ttatgaatct ccatcatctg ccttagtgaa aatgtaccta
     2161 aaaggagact ttggtaaaaa tgcatcagat gtagacccat atatagcatc aacttttttt
     2221 acagctgata ggtatgcatc atttaaaacc gattgggagg agttttacaa tgaaggtgga
     2281 ataattatcg cagatagata tacaacctct aatatggtac atcaggcctc taaaatggat
     2341 atttgtgata gagaagagta tttaaattgg ttagctgatt atgaatttaa tttatttaag
     2401 ataccacaac ctgattgtgt tatattttta gatgtgccta ttgaatttag taaaaagctt
     2461 atggagaata gaaaaaataa aattacaggg gaagaaaaaa aggatattca tgaaagtgac
     2521 atagagtatt tagagaaatc ttacaacaat gctttatata tagcagataa atatgattgg
     2581 aaaaaaataa attgtgtttt agataacaaa ttaagaagta ttgaaagtat acataatgaa
     2641 atttataaaa tagttcttga ttcaataaaa cctatggaga gataaatatg tattttgaaa
     2701 atattatagg gcaagatttt gcaaagaaat atttaacaaa ttctataaag aaaaataaac
     2761 ttaataatgc gtatatgttt gaaggaatgg atggaatagg aaaaaagaaa tttgcagatg
     2821 aattatcaaa actattactt gattatgaaa atctcgaaaa tagtccagac tatgtactca
     2881 taaaaccaga tggaaatagt ataaaaatag ctcaaatcag aaatttacaa tcagatatag
     2941 taataagacc tcataaagac tataaaatat atataatcaa taatgctgaa aaaatgactg
     3001 tggaagctca aaatgcactt ttaaagacgc tagaggaacc tccaaactat gctataataa
     3061 tcttagtcac aaacaacaag gaatctttat tagaaactat aaaatctaga tgtgatataa
     3121 taaagttctc acctatacca attgaagact taaaacgtta tttgataaat acaggtatag
     3181 aagaagaaag agctcaatta ttggctattt tttcgagagg aagtattgag aatgctctaa
     3241 atctatctca gtcttctgag ttttcaatga tgagagaaga tatacaacag tatattcaga
     3301 taatgttaga taaaaacata gtggagattt taaatatacc aaacaatatg gaaaaatata
     3361 gaggtaagat tatagcttta ttagatatga tgataaacta ttttcgagat atcatcctat
     3421 taaaagaaaa tgtaaacaag aacatgttaa taaatgtaga taagctagtt ttcattcaaa
     3481 atatgagtgg aaaaattagt tattctcaat tgtccaagat tattgatata atagaagatg
     3541 caaagagtaa aataaaaagc aattgcaatt tcaatataag catacaagtt atgtctttaa
     3601 atatatacga ggtgattaaa tgataaagat agtaggtata aggtttaaaa gtgctgggaa
     3661 aatatattat tttgaccctg ttgattttaa tatagagcaa gatatggatg tagttgtaga
     3721 aactgcaaga ggcttggagt atgggaaagt agtcgttggt ccaaaagata tggatgaaag
     3781 cgaattagtt tctcctttga agccaattat aagaatagct acagaagaag ataaaaaagt
     3841 atatctagaa aataaggaaa aggcaaaaga aacttttgag ttgtgccaac aaaaaataaa
     3901 agaacatgag ttaacaatgt ttttaataga ttgtgagtat acgtttgata ggaataagtt
     3961 gattttttac tttacagcag aaggaagaat agattttaga gaattggtaa aagacttagc
     4021 tgctatattt aaaactagaa tagaacttag acaaataggt gtcagagatg aagctaaatc
     4081 tataggaggt ctagggcctt gtggtagaaa actttgttgt tcatcttggt taggtgattt
     4141 tcaaccagtt tcaataaaaa tggcaaaaga ccaaagtcta tctctaaatc caacaaaaat
     4201 atctggaata tgtgggagat tattctgttg cttaaaatat gagcatgatg tatatagtga
     4261 agcaatagaa aaaatgcctg ttgtaggtgc attggtgcaa tcagatgatg gaaaaggaaa
     4321 agttgtagaa gtgaatcctt tattagaaca aattaaagtg gaatttcaag acaagacagt
     4381 aaagatatac acaagagaag atataaaaat acttagagag cctaaaaaat gtgatggctg
     4441 tggtggtaaa tgtaaggata atgatggatt agatgaagcc acactaagag agctaaagaa
     4501 attagaagat taaatttaag gtagggcttt tcctaccttt tttaaagcaa ttaatgctta
     4561 aagttattaa tatttgagga gaatttatat atgcaattaa aagattcaga aagaatagat
     4621 gatttacaat taaaaggcct taaaattata caagatacta atggtttttg ttttggtata
     4681 gatgcagttt tattagccaa ttttactaaa ataaaaaaag atgccaaagt agtagatttg
     4741 ggtactggaa ctggaattat acctattttg atagctggaa aaagtgaagc taaaaaaatt
     4801 attggcgtgg aaatacaaga agatgtatat gaaatggcaa ctcgttctat aaaattaaat
     4861 ggattagaag aaagagttga gattataaat gaagatataa aatacataga caaagtctta
     4921 gacataaatg gttaccatgt agtcacatca aatcctccat atatgcatat tgatggaata
     4981 aaaaatccaa atgataaaaa agcaatatca agacatgaag taaggtgcaa tttggaagat
     5041 gtaattagag cttcatccag attggttatg cctagaggaa aattcttcat gatacataga
     5101 ccaacaagat tggttgatat aataacttta gggagaaaat ataaattaga accaaaggtt
     5161 attcaatttg tgcatccaag acctcaaaaa gcaccgaact tagttttggt tcaatttgta
     5221 aaagatggaa gaccagagct taaaatattg gacccattgt atgtttatgg agaagatggg
     5281 aattatacaa aagaattaaa agcaatatat aataataaag atataggaga gttgtaaatg
     5341 agtgggaaat tgtacatatg tccaacacca ataggaaacc tagaagatat aacatataga
     5401 actttaagaa cattaaaaga agtagacttg attgcagcag aagatacaag acatagtata
     5461 aaacttttaa atcattttga aatctcaaaa ccactaacta gttatcatga acataataag
     5521 gattcaaagg gagattattt gataaataaa ctaattgatg gtgaaaatat agctctgata
     5581 agtgatgcag gtatgcctgg tatatctgac ccaggagaag agataataaa acaagctata
     5641 caaaataaca tagagataga agtattgcca ggtgcaacag cctttgtaac ggctttagtt
     5701 ggctctggta tggacacaca tagatttgtt tttgagggct ttttagatag agataaaaaa
     5761 gttaggaaag cacaattgga agaattaaag gaagaaagta gaactataat tttctatgaa
     5821 tcaccacata gattgaagga tacactaaaa gatatgctta aaattcttgg taataggaat
     5881 atttctataa atagagaact tacaaaaaaa tatcaagaaa taataagaga aaatatagaa
     5941 actaccataa aaatatttga ggaaaaagaa gtaagaggag agtttgtatt aatagtagag
     6001 ggttttcatg gtgagaagtc aaagaaagaa aattatgatg ggcttacaga tagggaatat
     6061 gttttaaaac taattgaaag tggtatgaac aaaaaagatg caataaaaat agtttgtaaa
     6121 gatagaaagt taaagaaaga tgtggtttat aaacaagttt tagatttata aaacctgaat
     6181 ctgaggtgat tttatggaaa tagggaaaat tataatagag agtttaaaga gggaagatac
     6241 acataaaata tttatagaat tagataataa gcatgaatta gaaaaaataa ttcctaaaat
     6301 aagctgtatg aagtctgtag gtgaatgtaa atatcatgta gtaaattgtt ttgaacattc
     6361 tataaatgca ttaaaagaat tagaaatagt attaaatgat aaggattttt ttccaataca
     6421 tctaagaaaa catgtgtcaa actatttaaa cacatatatt gaagaaggaa taaataagtt
     6481 acatgtatta aagttgggaa catttttaca tgatataggt aagcctgata gtatgacctt
     6541 agatgaaacc ggaagagttc atttcacaaa tcatgaaaaa ataggtgctc aaataattga
     6601 caatatggga ataaagttag agttatcaac agagacatat agacttataa gtaaatatgt
     6661 aagatatcat atgatacttt tgtctctata taagaaaaat gatttgagta ggaaagaatt
     6721 aattaatgta tttaacttag tagatgagga cactataggt gtaataatgc ttgggtatgc
     6781 agatatagtg tctacagtaa aattattggg caagagtgga gaagtcagtg tgttaaagac
     6841 atatatggaa tatattttaa caaattactt gtataagagt aattatacac atgtataaat
     6901 ttagttaata taattgagtt ttagatgatt aattgaagtt tgaaatatac ggatttcaaa
     6961 aacataaaag aagttgtctt tgttgtaaaa ttatgaaaga caactttttt tatatcaaaa
     7021 attgaaattt tattaaggat acttaatggt ctattaatta ataaaccatt agtatttaat
     7081 ttatattaca atattgattt tgcttgtatt ggcgttgata gtataacaga ggtcttagta
     7141 gaaccaattt tctttatagt atcaatcaca ttttctagct cgtacatatc ttttacaatt
     7201 acttttaaaa gtaagcaatc atcacctgtt atatggtgac attctacaat cctagggtcc
     7261 tttgcagctg actcaataaa ttctgtatat ccattgcttg gaagagaaat atgaataaat
     7321 gcctttataa ctctgcctaa tgaatctggg ttgacaatag ctttatatcc ttctataaca
     7381 ccagactctt ctaatctttt gactctttct gaaactgcag gagaagttaa accaactatt
     7441 tttcctaagt ccttcataga aattctccca tcatcctgta aaatttctat gattctgtaa
     7501 tctgtaacat ccataaataa acagtccccc ttaaataaaa ataattaata ctataaaact
     7561 tttttagaat ctatcatttg tgtttttaaa taccaaagat ttctagataa atcaacctta
     7621 taaatgtgtg gttttgaaag tcttttgtat tgttcccaga tagtacttaa ttcatattgt
     7681 acatgatttt ttatttcaag aacagctttt ttattatatt tgcatctgcc ttttatatac
     7741 aatggtttaa gaagctcttt aactttgtaa tttgtaaata cctttgtttt ccatgtataa
     7801 gtaggatgga agatttctaa aggtttagac tcatctataa cttcatcatg taacataatc
     7861 aaatctgcct ctgccttatt gtcttcgtta tatattctta taactttctt gtaaccagga
     7921 ttatttattt tttctggatt ctcagaaatc tttatcttag gttcaagaac tcctttttca
     7981 caagatgcag ctaatttata aactcctcca agagaaggtg aatcgaaaga tgtaatgagc
     8041 tttgtaccta ctccccatga atttatagta gctccttctg ctttaagtga tgttatggta
     8101 tattcgtcta ggtcattaga tgcagtgatg ctgatatctg aaaagccagc gttatctaat
     8161 tgttttttag cttctttaga taaataagct aaatctccag agtcaagtct tatacccata
     8221 ggtttgtatc ctttttcaga aatatttttg aatactttta ttgcattagg aactccactg
     8281 tttaatacat cataagtatc tacaagtagt aggcatttat ctggataaac atcagcatat
     8341 gcttggaatg cttcaagttc attatcaaat ttttgtaccc aactgtgagc ttgtgtacca
     8401 attataggta tatcaaacat tttccctgct agtacgtttg cagttccagc acaaccacca
     8461 actacagcag ccctagctcc atatatccct gcatctggac cttgtgcacg acgtaatcca
     8521 aattcaaata cagggtctcc ttgagctgca aagcaaactc tagaggcttt agtagcaata
     8581 agagactgaa aattaactat tgttaacaat gctgtttcaa taagttgagc ttgatataaa
     8641 ggtgccttaa cagtaattaa tggctcatta gggaacatga tagttccttc ctcaacagca
     8701 tatatatctc ctgtgaattt aaattctttt aaaaatttta aaaacttgtc agaaaataaa
     8761 tttaagtttt ttaagtactc taaatcttca tctgaaaaat gaagattatc tatgtattca
     8821 acaacctgat caataccaca aactatagta taccctccat cacaagcgtt ttttctaaaa
     8881 aacatatcaa atacaacaat gtcttcatga atattctttt caaaatagcc atttaacata
     8941 gtaagctgat ataaatcagt aagaagtgtt agatttctca ttatttctct ccttaattat
     9001 tattaaatat taaaaattgt aaaaactccc acacttatac taaaacataa tatagtacaa
     9061 ctttcaagta taaagtatta cctaactatc ataaaattat ttaaagagga ggatgattat
     9121 aataggaaaa atatggtttt atatggtatc gataggaata ataggaagct tgatttctaa
     9181 aaatatgggt gaattaaata aagttatatt aagtgaaaca tcaaaaggta tagagtttgc
     9241 aataagtcta gctggtatca tggcactctg gatggggata atgaatatcg caaaagaatc
     9301 aggtttaatt gaaaagatag gtcaaaaact aaatcctata atgagaagat tatttccttc
     9361 tattccaaag ggtcataaag caatgtctta tatagttatg aatattgctt taaatatgtt
     9421 gggtgctgga aatggtgcaa cagcatttgg tttaaaagca atgagtgagc ttcaaacttt
     9481 gaataacaag aaagatacag ccactaatga tatgattatg tttatggtaa tcaatatatc
     9541 atctatacaa ataattccat ttactataat caaattaagg atggatatgg gggctcaaaa
     9601 tccaagtgaa ataattttta cgactttatt tgcaaccata atatctacag cagtagcaat
     9661 aataacatgt aaattttttc aaagaagata tagataaagg ggatgtagat acatggagat
     9721 attttcaaac ttacttatac caataataat tctgtacata gtagtttatg gtaaatataa
     9781 aaaaatagat gtgtatgata gttttgtaaa aggagcaatt gatggattaa aagcagcatg
     9841 ggatatccta ccatatataa taggtatatt tttggcaata ggaatattca aaactggtaa
     9901 aggtcttgat atgttagaat ggctatttac accaatagca aatatgatga gtataccaaa
     9961 agaattaata ggtctaataa gtgtaaaacc tttatctgga agtggtgctt tagggatgta
    10021 cagtgaactt gcaaatagag ttggaatagg aagtttagta gaaaaaatgg gtgctacgat
    10081 tgtaggttct tctgagacta ttttttacac aatggcaata tactatggaa gtctgaagat
    10141 aaaaaatact agacatacat tatcatgtgc tatgattagc catgttgcag gtgtcatagc
    10201 agctgttttt atttgctatg taatatttgt ataatttgtt gacaatatgg gaaaaatttt
    10261 ataatatagt gattatatag aaacaaatag taatacaaat tacaagctat gaaaagaaga
    10321 gtaaataaag gttttttcta tcagagagct aggttaggtg aaagctagtg tcaaaagctt
    10381 tattgaagat ggtcttggag ctttttatct gagcaagtgt gctagggtaa aacggttgga
    10441 cacgttatag tctactaagg tatctataaa atgtttctac atttcatgtg aaacataact
    10501 attatagatg aattagggtg gtaccgtgaa taatctcgcc cctatgttaa ctcataggag
    10561 gcgatttttt attatttaaa tgaaagaatc atatgattac gaacgataaa aaattaggag
    10621 gtaaataaca tgagcaaacc gagtttttat gtaacaacac caatatacta tccaagtgga
    10681 ggattacaca taggacatac ttattcaaca gtagctgcag atacaatagc tagattcaag
    10741 cgtttctgtg gatatgatgt aaagttctta acaggaacag atgagcatgg tgaaaaaatt
    10801 caaaagaaag ccatagaaca aggaatgtca gagatagagt atcttgatgg aatgataaaa
    10861 gatataaagg ccttatggaa tactatggat atatcttatg atgattttat aagaactaca
    10921 gaaaaaagac atacagacat aatacaaaag atatttacta aactatatga gcaaggtgat
    10981 atatataaag gtgaatatga aggtagatac tgtactcctt gtgagagttt ctggacagaa
    11041 tctcaattac tagaaggaaa taaatgccct gactgtggaa gagaaacata tttagtaaaa
    11101 gaagaatctt atttctttag attatctaaa tatgaagaca gattaaaaga gttatttaaa
    11161 gatgatagtt tctgttttcc tgctgctaga aaaaatgaaa tggtggcaaa ctttttagac
    11221 aaaggattag aagatttaag cgtaactaga acgacttttg actggggtat aaaagttcct
    11281 tttgatgaaa aacatgtaat ttatgtgtgg gtagatgctt tatgtaacta tataacagca
    11341 ttaggttata tgactgataa tgatgaagaa tttaaaaaat attggcctgc caatgttcaa
    11401 atagtaggta aagaaatagt gagattccat acaataatat ggccagcgct tttaatggct
    11461 ttaggtctag aagttccaaa acaagtattt ggacatggat ggatactatt tgctgatgat
    11521 aaaatgagta aatcaaaagg taatgtggtt tatccagaac ctataataga aagatatgga
    11581 atagacacac ttaagtactt cttattaaga gagtttgcat ttgggcaaga tggaagttat
    11641 actcatagaa attttgtaac gagaataaat tatgatttag caaatgattt aggaaactta
    11701 ataagtagaa ctgtagctat ggttgaaaaa tacaataatg gtataatacc aacagcaaaa
    11761 gtttcaactg attttgatgc tgacttaaaa gaacaagctg tttcaactag agaaaacttt
    11821 gaagctgaaa tggataaaat gcaattccat gaagcattag agagtgtatg gaaattagtt
    11881 agaagaacta acaaatatat agatgaaact atgccttggg cactagctaa agatgaaacg
    11941 aagaaagatg aattagacac agttttatat aatttatgtg aatctataag aataatcgca
    12001 acactaataa atcctataat gaatgagact gctaataaaa tatatgaaca tataggaata
    12061 aaaggtcaag atgatataac tacatgggaa agtacaaaaa catttggtct tattggagaa
    12121 aatgtaaaag tatttaaagg tgaaccttta ttcccaagat tagatgtaga aaaagagata
    12181 gaagaattaa ctaaaatgtt ctctgggaaa cctccagtag aagaaaaacc tttagagcat
    12241 aaagaagaaa ttactattga tgatttagac aaaatagagc ttagagtagg gaaaataata
    12301 agctgtgaaa aacatccaaa agcaaataaa ttattagtat cacaagttaa gattggacca
    12361 gaaacaagac aaatagtatc aggaatagct gaatactata agccagagga tttagtagga
    12421 aaagaggtta cagtggtatg taacttaaaa ccagttaaat taagaggtgt agaatctcaa
    12481 ggtatgatat tagcagcagg tgatgatgga gacccatatg ttttaccatt tacacaaggg
    12541 gctaaagatg gatgcgaggt tcgttagtag gtaattaaat agtaaggaga ttaaagatgt
    12601 tatttgactc acatgcacat ttaaatgatg aaagttttga tgaagataga gatgaactta
    12661 ttggttcatt aaaagataaa ggtgtagatt tggttgtaaa tccaggagca gatatagaga
    12721 cgtcgataac agcaattgaa cttgcgaaaa aatacgactt tatatattca gcagttgggg
    12781 tacatccaca tgatgtatca aaactagatg atacagcaat agaaactcta agaaaacttg
    12841 caactgagaa tgaaaaagtt gtagctattg gagagattgg attagattat tattatgatt
    12901 attctccaag agaagaacaa aaagagtggt ttaagaagca aattgaatta gctaatgagc
    12961 taaaacttcc aataataata catgatagag atgcacatgg agatactttt gagataataa
    13021 agaatactaa aaatcctgaa ataggatgtg tacttcattg ttatagtgga aatgtagagt
    13081 tagctagaga atatgttaag atgggttgtt atatatcaat tccaggcacg gttactttta
    13141 agaataataa aaaaactaga gaagtagtaa gagaaatacc tctagaaaga ttattcatag
    13201 agactgattc accatatatg tcaccagagc cacatagagg aaagagaaac aatccttctc
    13261 aagtatcttt tgttgctgat aagatagccc aggaaaaagg gatatgttat gaagaagtat
    13321 gtagagttac aaaagaaaat gcaaagaaat tttttaatat aaaatagaca aattaaatct
    13381 tataatgata tatataataa gtcattataa gtataggatg agagtgcctc aaaatgagtt
    13441 ttttagttca tgaggcactc tttttttatg aaatcaaata tattttcatc atttcaacaa
    13501 tgaaaaagaa gtttatcata ttttgagaca gtttgttttt atttgtttaa ttcatatttt
    13561 aaaatatatt ttcttaacat tgttaaaaaa gaatttacaa gatattcatt agaattaact
    13621 caactctaat attcacttaa cttaagtggt ttattatatt attaaagaga agtaaacgaa
    13681 aggtagatta aggaggctaa attttgtata cagttgatag tactaagata ttgataaata
    13741 tgaacttaga gaaactagaa aagatatact caatgataaa agatacatca agtatttcta
    13801 taattaaaga acctaacttg gctacagtaa tggtaagagc taatgaaagt gtaaaaaata
    13861 caacatttaa tttaggagag atattagtta ctgaatgtag tgtaaaggta gatgaaagct
    13921 tgggttacgg aatagtttca gaaaacaata ataagaaagc catttactta gcagttatag
    13981 atgcagtttt acatagcaat aacagtaaat ttgatgagtt aaagaattac ataaataaaa
    14041 gtgtatatga agagaactta aggtatgaac aagagattat tgatgaattt agcttgatta
    14101 ataaaacgaa agttcaattc aatgctatgg attaaatagg aggagaatca tggtaaatta
    14161 tacacaagaa atatatagaa agatgctaga tagtgcttcg tttcctggga aattaaataa
    14221 tatagataat ataaatatag aaaataatac aaaactattg aatggagcaa ttggtatagc
    14281 aatcacttta ttagaccaag aagttacctt ctatatagaa aattatactc aaaaagatat
    14341 aaaaaatata agagcgctta cagtgtcaaa tcaaatagat tatagaaaat cagattatat
    14401 atttttagat attaattcag aagtggatat attacagatt aaaataggtt cttttgaata
    14461 tcctgatgaa agtgcaacta tagtacatca agtaaatgat ttatcaacgt actctcaaac
    14521 taagtatata aagcttgatt tgagtggtcc tggtataaaa tctaaaaata gtatatatat
    14581 aaatggaatt agagaagaat ttatagaaag attatctacc ataaataaag attatccaat
    14641 aggaatagat ttgattttag tagataaaaa aggagaaatt gcatttatac caaggtcatc
    14701 aaaattaagt tgggaggtat tgtagaaatg gcttatgtag cagttaaagg tggagaagaa
    14761 gccatattac aggctaaaaa tatacttgag ttttataggg taaaaggaga tagcttgcct
    14821 atagatgtaa agcagattga ggaacaaatg tcttatgctg tagacaaagt aatgtctgaa
    14881 ggaagtttat acaacaagga actatcagca ttggctataa aacaagctca aggtgatata
    14941 ttagaagcct ctttctatgt aagagcttta aggtcaacaa tgcctagaat tacatattca
    15001 gaacccataa atacagaaga aatgagaata aaaagaagaa tatcagctac ttttaaagat
    15061 ataccaggag gtcagtatct tggggcaact agagactatg aaaatagaat attaaatgta
    15121 gaattattag aagaagatga aaaaaagaat agagatttta gagatagttt tataaatgaa
    15181 ttagaaacag tagatgaaat ccctgaattt acaaaaatat ctaatatatt tagaaaagaa
    15241 aatttattac aagaagaagt ttgtgaaaac aaattggaag aagttattga tgatattaca
    15301 agaaatagtt taagatttcc agtttctagg tcagcaaagt tacaggcatt gactagaggt
    15361 gaaagtggag tagtgtcagg ttttgcttat gctattgtaa gaggttttgg tgatgaacat
    15421 ccatatataa gtgaacttag aactggtaat gtatttataa aagtaaaaca tcccatctat
    15481 gaagatgaag aaataataat aggtgatatg ctggttactg aatgtgaaat agtttcaaaa
    15541 gcatcacaaa ataagactga aaattctaaa actaattcgg aagataaaaa taagatgtct
    15601 ttaggatatg gtctttgtat ggggaataat gagaataagg ctatatctat ggccatacta
    15661 gacaaatctt tggagccaaa tagtgaaaaa ctagcacaag atgaagaatt tgtattgctt
    15721 catatagatg gaatagattc attaggattt atatctcact ttaagcttcc tcactatgta
    15781 gattttaaag cggatgtaga aagaataaaa tagtttgtgg aggtaagttt aggtgatata
    15841 taactatggt tttttagacg aaaacacaaa aaaagaaata agaagaaaga tattaaaagc
    15901 aatatcaata cctggttatc aagttccctt tggttcaaga gagttgccta tagctaaggg
    15961 atggggtact ggaggtttac aattaacact atcattaatt ggtaaaaatg atgtagtaaa
    16021 agtaattgac caaggaagtg atgattctac aaatgcttgt aatataagga gctttattgc
    16081 aagtgtaagt aatgtagaaa ccacaaaaga tacattagaa gctacattga ttcaaacgag
    16141 acatagaata ccagaagaaa aacttaaatc taatcaaata ctaatatttc aagtaccaat
    16201 accagaaacc cttagaatag tagaacctag tgaagtagaa acaagaagaa tgcattcaga
    16261 agaagattat agtaggatgt gggtatatct ttatgaagat atagttagat ttaatgatat
    16321 atctatagca gttgaatatc catgtaaagt aaatgataga tatttaatga atccatcacc
    16381 tatacctaga tttgatataa aaaaattaaa tatgtcagac aatttattct tgtttggtgc
    16441 aggtagagaa aaaagaattt atgctattcc tccatataca aaggtagaac ctttagagtt
    16501 tgaggattat aagtttgaag aggaaaagtt tgaaggaaaa tactgtagtt tatgtaacag
    16561 tacaaataca tttttagatg aagtatatga cagtgacact aatgaaaagt actatagttg
    16621 ctcagataca agttattgtg aaaaagttag attaaaaaat aacagtatag atgtgacaat
    16681 aggaggtact tggaatgagt aaaataaatg tctctaaaag attagaaaat atagacaagc
    16741 aagtattaat aggaagaaat atcaatctta tttatggaga tgggtgtgaa aagtgttttg
    16801 aaagcacagg atatgaaagc aataatatat gtaagtattg tggttctata gttgcatgta
    16861 ataatgtaaa tttagaactt tatgaaggag aagtccttgg aattgtaggt gaatctggtt
    16921 caggaaaaag cactttatta aaaatactgt ttttccaaga acatgcaaat agtggagaag
    16981 tatatatatc ccattacaat aaagacacaa atatactaga gctttcagac caaaaaaaga
    17041 gatacataaa gaatcatttt atgggtattg tgtatcaaaa tccccacctt ggtttaaatt
    17101 tagactttag tagtggtggt aatatagcag aaaaattatt gatggcaaat ttatataatg
    17161 ttgaaaaaat aagagataga ggcaaagaac ttttaataaa aactaatata cctgtagaaa
    17221 gaatagatca taaaccaaaa tactttagtg ggggaatgca acaacgagtt caaatagcaa
    17281 aagctctttc aaataaccct ccaatattgc tattagatga ggttacaaca ggtttagatg
    17341 tttctgtgca agcggaagta ttggatttaa taagagaaat ccaaagagaa cttaagattt
    17401 ctatgatagt tgtatcccat gactttgatg ttataaagat gcttgctgat aggacaattg
    17461 taatgaaaaa tggaagtgtg attgagtctg gtcttacaga ccaaataatg gaggacccac
    17521 aacacccata tactcagcaa cttataaatt cattgctata aatatcgttt gtaaataagc
    17581 aaaatggggg tttttaataa aatgaaagaa actatacttg aagtaaataa ttttagtaaa
    17641 gactttgagt tacatgcatt gaacaagact ataacggcat gtagtaatat aagttttgaa
    17701 gtttcaaaag gtgagttttt aggaataata ggtaaatctg gagcaggtaa gtctaccata
    17761 ttaaaaagta tctataaaac atatatacca acaactggag aaataatttt taattcagaa
    17821 atatatggta atgtagacct ggctaaaatt ggagaccgag aaatgataaa tcttagaaag
    17881 aaagaaatag gatatgtatc acagttttta aagacacttc cacgaataac tgcaattgaa
    17941 ctggtagtac attctttaat tgagagtggg tttgaaaaag attgttcgta tgatatggca
    18001 aaagatatac ttaaccaatt tgaaataaag gaaaatttat gggatgcgta tccaaataat
    18061 ttttctggtg gagaaaaatt aagattaaat ttagctcaag ctatggttaa aaagcctaga
    18121 cttttgttac ttgatgaacc aactgcatca cttgataatc aatctaaaat atatgtaaaa
    18181 gaaaaaatgt tggaacttaa aagtcaagga actacaatga taggaatttt tcatgatata
    18241 gagtttatgg aaactgttat agataagacc tttactatgg caaaagggac tataagtgaa
    18301 agtggggtag cctagatgat aaaactaatt cataatgcaa atattgtatt agaagatatg
    18361 attttagaaa atggtcattt aatcatagag ggagatacaa taaaaaaagt atcaaatgat
    18421 aggattgatt acgcatttga ctttaatgag atagatgaaa taatagatgc aaaaaactta
    18481 tatgtaatac ctggtattat agatattcac agtgatgcca ttgaaaagga aatagagcca
    18541 agaccaagta cattattacc atttaatatg gcattttatg aactagataa aaaactacct
    18601 gcaaatggaa taactacagt ttatcattct atatctttag gggatggagt aggagttaga
    18661 agtattgata actctttaaa gatgattaaa aatattgatt catataaaaa tatagatagt
    18721 aagagtataa atcataaagt tcatttaaga tatgaagtgt tgtattatga aggtttagaa
    18781 aaggttttag aactattaga tgaaaataaa atagactact tatcaataat ggaccattct
    18841 ccaggacaag gtcagtatac aaatccaaca ttttataaag agtatgctac taaagtgtgg
    18901 ggagttacag aaaattatgt agatacatgg ttagatgatt tagtaaatct gcatgataat
    18961 ttagattgga ataaaatagc taatattata ggtatagcca aaactaaaaa tataaatgtt
    19021 gcatcacatg atgatgatac attagaaaaa atggatttca taaaaaatat aggcataaat
    19081 gtatctgaat ttcctataac tcttgaagtt gcaaaacatt caaaaaaatt gggtgttcta
    19141 acttgtttag gtgcaccgaa tattgtaaga ggtaaatctc ataataacaa tttaaaagca
    19201 atggatgcta tattggaaga ttgttgtgac attgtgtgtt cggattatct tccatcagct
    19261 atgataaagt ctatgtgtat agttgcagaa agaataaata atttaaataa agcagtcagt
    19321 ttatttacct caaatcctgc taaagcagtt ggtatatatg atgaaagagg tagtataaaa
    19381 gaaaataaaa aagcagattt agttttagta gatattgata gtgaatatcc aaaggtttta
    19441 aatactattg taaatggaaa aacagtttat aaaagggagg tataaaaatt gctaacagag
    19501 ttacattgtc atacaagtat atcagataat aattttacta ctgaagaaat aataaaaaaa
    19561 gcagcagaaa agaatataaa tatcttagca ataacaaatc atgacacatt atctggattg
    19621 gatgaagctc ttgtgcttgg agagcattat ggaataacaa taataccagg tatagaaatt
    19681 tcagcctatg attataaaaa tagaaaaaga gttcatattc ttggatataa catagattta
    19741 aacagtcaag aaataaaaaa tttgtgcaat ccaatggtat gtgacagaca taaagcatct
    19801 gttaagatgg taaataaaat tatagattta ggatacaaaa tatctttgga agatgtaaag
    19861 aaatattcat caaagactgg aatatttaaa caacatataa tgaaagctct tatagataaa
    19921 ggatatacag ataatatata ttcaagtcta tataaagaat tgtttcatag aggaaacggc
    19981 aaggtatatg tatctttaaa atatgtggat tacagagatg caataaaagc tataaaaaat
    20041 tctggtggaa tttgtgtgtt agctcacccg ggtcaaatgg ataattttag cgctattgaa
    20101 gagatggtaa aagtaggatt agatggaata gaagtatatc atccatctca caacaaagaa
    20161 ctagaaaaag agtcgctttc ttatgctaag aagtataatc tagtggtcac aggaggctca
    20221 gattaccacg gattttattc tcaacataat tatgaacttg gaagcaagag cttaaataaa
    20281 gaagatttat ttaagtttag gttagcttta ggaggggtat tataaatgtc ttttttacaa
    20341 gtaaaaaatg taggtaaaag ttatggacaa gttaaggtgt taaaagacat atctattgat
    20401 attgaaaaag gagagtttat ttgtttacta ggtccaagtg gttgtggaaa aagtacactg
    20461 cttagaataa ttgcagggct tgaggataaa catggtggaa aaataataat aaatgataag
    20521 gatatgacta attcaccacc tgaaagtaga aattttggta tagtttttca atcatatgca
    20581 ttatttccaa atatgaatgt ttacaaaaac atagcctttg gactagaaaa taaaaacata
    20641 agtaaatcta atattgataa aaaagttaaa gaagttctag acgttgtaga attaagtgga
    20701 tatgagaaaa aatatccatc acaattatca ggtggacaac aacaaagggt tgcattagct
    20761 cgtgcgattg ctttagagcc agacttttta cttcttgatg aacctttatc tgcattagat
    20821 gcaaaagtaa gacttaaact tagggagcag attagaagtt tacatagaaa actaggcatt
    20881 acaactataa tggtaacgca tgaccaagaa gaagctcttt gtttagctga taagatggtt
    20941 gttatgaata gaggagaaat aatacaagtt ggaacgccaa aggaggtata taaaaatcca
    21001 gaaacacctt ttgtagctga ttttatagga acaataaatt ttatagatga tggtattaat
    21061 aagatagcta ttagaccaga agatataaaa gtagagtcta atagagattc taaagataag
    21121 gatataaaag tgggagaaat tttagatatc gaatttagag gatttaacta tagaattaca
    21181 gttgagtatc gttctaagca aatgaaatta gatgtagttt ccaaagttgc agaacaaatg
    21241 aaactgtgca taggttctaa aataaacttt aagataccta aagaaggaat tgtacaatat
    21301 aaatcagagg gatgtgctta atagctaggg gtgaataaat gataacatca aaaaataaaa
    21361 gaagaataag tgatagcaca atacaaaaat atttcttgat tttttcggta attgtactaa
    21421 tagtatttat attatttcca ttagtatcat tattaaaaaa tgcatttatg gatacaagtg
    21481 gaaattttat aggaatttca aactttagta aatatgttga aaatccaagt cttatagcat
    21541 catttaaaaa ttcaattttt gtatctacag tctcatcttt aatatcacta tgtttagcat
    21601 ttatatattc atacgcaata acaagaacaa atataaagtt taaagatttt tttaaaacta
    21661 tgggaatgtt tccacttttt gcaccaacta tgttatatgg tatttcactt atataccttt
    21721 ttggaaataa gggaatcttt acaaccatgg gtctggaagt accactatat ggtccattag
    21781 gaataattat ttctcagatt ctatttacat ttccacaagc ttttttaata ttatctgtag
    21841 cactttcgat ggctgattat agactttatg aagcagcaga tagcttgggt gctagtgaat
    21901 ttaagaaatt ttgcaaaata acaattcctg gtataaagta ctcattactt agttcattct
    21961 ttgtatcctt tatacttgca tttacagatt ttggagcagc taaggtagtc ggaggaaact
    22021 acaatgtact ggctactgac atatataaac aagtagttgg acaatttaac ataccaatgg
    22081 gagctactgt ttctatggta atgttaattc ctgtactaat agcatttaca ttagataaga
    22141 tggcaagtaa gaaacaaggt atgaccataa ctgcaaagtc tatgccatat aagattaagg
    22201 aaaataagtt tagagataga gtatttttaa tagtatgtag ttttataaca ttgctaattt
    22261 ttattttaat attcgtttca gttataggtt cagttataaa gttatggcca tataatttaa
    22321 gctttacaat ggaacactat acatttaaag gtattttggg aagtggaata aaaacatact
    22381 taagcagttt gaaaatatca actttaacag caatatttgg aactatattt gtatttttta
    22441 gtgcttatat aatagaaaag gtggataagt ttcctaaatt aagacaaaca gcttaccttt
    22501 tatcaatgat accaatggcc ttacctggct tagttttagg tatatcatat ataacttttt
    22561 ttaactcagc aagtaatcca ttaaattttt tatatggaag tacagcaata ttagttatag
    22621 taaatgtagt tcatttttat tcagtttgtt ttataacctc aaattcatct ttaaaaatgt
    22681 tggataaaga gtatgaatta gttgcaaaat ctataaatat tccattctat aaagtatttt
    22741 ttaatataac agttccgatg tctataacat caatacttga aatagtagta tattattttg
    22801 taaattcaat ggttactgtt tcagcattaa tatttttata tatacctcaa actcagactg
    22861 catcaatatc aatactaaag ttagatgaga taggatatat aggaccatca gctgctatgg
    22921 cagtattagt gctattaaca aatataatag taagactttt gtacgaattt gtaacaaaga
    22981 aattaaaaaa taacacacaa aaatggcagc aaaaagatgt tgcatagggg aggaaaaaat
    23041 gaaatttaaa aagctagttt ctttaggagt attatcaaca cttttattaa gtgtaataac
    23101 aggatgtagt actgattcat caggttcaga ttcaaagtct gatagtaaga caaaagggga
    23161 tttaacagtt tacacagcaa ttgaagaaga tagtatagag ccatatttag ctacatttaa
    23221 agagaaatat ccagatatta aattaaatat tgttagggca tcaacaggag atataacagc
    23281 aagattatta gcagaaaagg ataatcctca agcagatgtt gtatggggag ttgcagccac
    23341 aagcttattg gttgcagatg accaggggat gttagaacca tatgctccaa aaggttctga
    23401 agaaatagag tctgcattta aagatgataa agaagttcct tcttgggttg ggatagatgc
    23461 ttggatgaca ggtataacag taaacactaa agaattaagt gataagaaca tcccagttcc
    23521 tagttcttac gaagatttaa taaagccaga atataaaggt cttatatcta tgcctaatcc
    23581 atcttcttct ggtacagggt acttaacagt atcagccctt atacaaatta tgggggaaga
    23641 aaaagcatgg cagtatatgg ataagttgca tgagaatatt ggtgtataca ctcaatctgg
    23701 ttcagctcca gctacatcag cagcttcagg agaatatcct attggtatat cttttggata
    23761 tagaggtata aaattaaaag aggaaggcta tccagtagaa gtagtatttc caaaagaagg
    23821 ttctggatgg gatatagaag caaatgctct tgtgaaaaaa gataatataa aagaagcatc
    23881 aaaagtattt ttagattggg ctataagtaa agatgcaatg aatgaatact ctaagaacta
    23941 tgcagttact actatttcta caggaaatcc aataccagaa ggattcccta aaaagccatt
    24001 agagcaaatg atagataatg atttaaaatc agcagcaaaa aatagagaag atatactaaa
    24061 taaatggata tcaaaatatg atggtaagac agaaaaagag agttaagtaa aactatacaa
    24121 atggagtaaa aagaaaaaat ttttttaagt agattttatt ataataatat aagttgagaa
    24181 taatataggt caagaaaagt gaatattcta taaaaatgta tagagtaagt ataccattca
    24241 gtttgaatgg tatatttttt atttttagag attaatttag aaatagatat actacagttt
    24301 aaaatagtat attttaattt cattattaaa gtatagatgt tatatataaa gtaaataaga
    24361 tattaaataa ttataaacta aagtaaataa aatattgagc gattattaaa aagatatata
    24421 tatatatttt aatttgagca gtttgttata tattataaaa aaagagaaaa ataaaaggta
    24481 aattgtttct ggataactta aaattggaag taagaatatt taactagaga agaattattt
    24541 aagttcaggt tagctctagg agtagctgat tttataggag caatagattt tatggatgat
    24601 gatataaaca tgatagcaat tagaccagaa gatataaggg tagaatttaa tagagatttc
    24661 aaagaaatta tagacctcaa actcagaccg tatcgatata aaaactaaag ctagatgata
    24721 tagtgttgta tataggacca tcagctgtta tggaagtatt agtgctttta acaaatataa
    24781 tagtaaaact tttgtatgaa ttgataataa aaaaattaaa aaccaagaca taaaaatggc
    24841 aacaaaaaga agttgaataa gggaggtaaa aatgaaattt aagaagttag tctctttggg
    24901 aatattatca acacttttat tgagtgtaat aactggatgt agtaatgttt catcaggttc
    24961 aaacttaaag tctaataata agacaaaagg agagttaaca gtttatacag caattgagga
    25021 agatagtata gatacatact tagctacatt taaagagaaa tatccagata ttaaattgaa
    25081 tgtacttaga ttatcagtag gaggtataac agcaagatta ttagcagaaa aagataatcc
    25141 taaagcagat gtgttatggg gtgttgcagc tacaagtttg ataattttag atgacaaaga
    25201 aatgctagag ccatacgctc cgaaaggctt tgataaggta aatcctgcat ttaaagatga
    25261 taagaaagtt ccttcttggg ttggaataga tgcttggatg actggtataa cagtaaatac
    25321 taaagaatta aaagctaaaa acatatcagc tcctaattct tatgaagatt taataaagcc
    25381 agaatataaa gatcttatat ctatgcctag tccagcttct tcaggaacag gatatttaac
    25441 agtatcagaa ctcatacaaa ttatgggtga agaaaaagca tggcagtata tggataaatt
    25501 gcataaaaat attggtgtat acactcagtc tggttcagcg ccagctatat tagcagcttc
    25561 aggagaatat cccattggta tatcttttgg aaatagaggt ataaagttaa aaggtgaagg
    25621 ttatccagta gaagtagtat ttccaaaaga aggttctgga tgggagatag aatcaaatgc
    25681 acttgtgaaa aaagataata taaaagaagc atcaaaagta tttttagatt gggctataag
    25741 taaagatgca atgaatgagt attctaagaa ttttgcagtt actacaattg acacgggaaa
    25801 tccggtgcca gaaggatttc caaagaatcc attagaacag atgatagata atgatttaaa
    25861 atcagcagca agaaatagag aggctatact aaataaatgg atagaaaaat atgatggaaa
    25921 gacagaaaaa gagagctaag ccttacaata aaatttagta caaaaagcgc ctagaatata
    25981 agttttacat ctaggctctt ttgatatatt tatttaaaat gcatatttct atataaaaat
    26041 aaatagttta gtaccttgat taaattaaat aaaaacctta aaataaagag atgtaaagaa
    26101 aaactaaaaa cgaataaaag gtgaatttat atgataaaag aaataatagt agtagagggt
    26161 agagatgacg ttacagcagt taagagagca atagatgcag aacttataac tacaggtgga
    26221 tttggatttc caaaaggtgt aatgcagcgt ataaaagctg ctaatgaaag acgtggtgtt
    26281 ataatattta cagacccaga ttttgcaggt gaaaaaataa gaaaaaaaat agcatcagaa
    26341 gttccaggat gtaaacatgc atttctacca agagaggaag ctaaaaagga tggagatata
    26401 ggtattgaga atgctactcc tcaaagtata atagcagctc tgaataaagt tagaactgaa
    26461 aatacagaaa aaagagatga atttaagcaa gttgacttaa ttagaaatgg tcttataggt
    26521 aatgaagaag catcacttag aagagatgca cttggaaaaa tacttggaat tggatatgga
    26581 aatgcaaaac aatttttaaa tagattgaat aattatggag ttgaaagaga agaatttata
    26641 gatgcattaa aacaaatcta aacgtaatgt ttaatgtatg aaaaatatgt atataaaata
    26701 aattgtggaa ttacggttaa tttaagataa attatttata atatatacct tattttaaat
    26761 caatgtaaat acatataaat aagtataatt aataaaatta aatatcaaaa taagttaaaa
    26821 aggagtaaat aatggataga ctatcttcac ataatgcaac aaaggaagta gtacaaaaat
    26881 ataattttaa attttcaaag tctttaggtc aaaatttctt gatagatagt aatataattg
    26941 ataaaatctt atctggagct agaatcacaa gaggagataa tatcatagaa gtaggacctg
    27001 gtataggaac tcttactcgt gagatgggta aaatagcaga aaaagtagtg gctatagaaa
    27061 tcgatagaaa tttaattcct atattgaaag ataccttgtc agatttagat aatacagagg
    27121 ttgtaaatca agatatacta aaagtagaca tacaggaatt agtaaaagat aaattaaatg
    27181 gtggaccagt taagcttgta gcaaatcttc catattatat aactactcca atagttatga
    27241 aatttttaga ggaagacata cctgtaacag acatagtagt catggttcaa aaagaagttg
    27301 cagatagaat gaatgctatt ccgggtacta aagattatgg ggcattatct atagctgttc
    27361 aatactattg tgatacagag attgtggcaa aagctccaag acatatgttt ataccacaac
    27421 caaatgtaga ttccacagtt ataggtttac atgtaagaga taaaagaaaa tatgatgttc
    27481 ataatgaaga catatttttt aaaacagtaa aagcatcctt tggacaaaga agaaaaactc
    27541 ttcttaattc gttgggaggt cttggttttc ttaataaaga tgaaataaga gaaatattaa
    27601 aagaagctaa tatagacgaa aaaagaaggg gtgaaactct tagtatagaa gagttttcag
    27661 ttctttcaaa tataataaat acaaaagtat cttctaaata gaaggtactt tttttaattt
    27721 tgttaacata tattgtttag agaaactgtg ttaagggggg attgcagtgg gttctaaaag
    27781 aaagtttaaa agagactata taatactaga agctaaagac ataaacttta gatacaaaga
    27841 acgagtactg ccaaaagctt ttgcaaaagt tgaagtaaat gatgaaaaag caattattgc
    27901 attatatgta gaaaatctaa aatatgttaa agatgggtat aaagcagtag caataaaaga
    27961 tgaccatgga ttaatagact taggaaatat aattttaaat gaacaaggaa gaggtgaatt
    28021 tgttttagat ttagaagatt ctgatgatga gataaaaggt attgcattat tgtatgaaag
    28081 aaatatacct ttaattggat ttaagggaaa taagcttgaa aattatgagg acatattatt
    28141 tcaagaggta gaggaagaag aatatgaaga atatgaagaa tatgaagagt tggaagaaga
    28201 cgaagagata gaggataatg aggaaagtga tagagacgaa gatagtgaag aagaatatat
    28261 tatagaagaa tatgatgaag atgagtatga agactattgg gaagatgatg aagatattga
    28321 agaaggagag ttaaaagcaa gaacggaagt agaagattct ggtgatgagg aaatagaaga
    28381 gttcaataat tataaggaaa tagaaaatta taatagggtt aaagtacagg aagaatatat
    28441 agacatagaa tatgatgagg aagaagagga agaagaagaa gtttttgaag taaatagaga
    28501 agaagatagg tttgtttcct caaaacctac taaatcaaag aaagttcaaa aagatcagaa
    28561 taatattgaa aaaataaaaa gagctaatgg agtaagtcaa ggagagagtg gaaataaaca
    28621 aaccagtaca ttacttatgc caagacaaat aaaaaaaggt ttgaaattat ttaaagaagt
    28681 aaaacctttt gtaacagatt atatagataa gacaagatgg tggaaaatag agataaatcc
    28741 tacaacactg tgtggatata caatgcctta tttaggatat ttaaacgtat tgaattacac
    28801 tatgtatagt gatgcagttt tacattcata taaatacaga cactatttat ttggtgttca
    28861 gtatgatgaa tataataaga gaaaacatta tatttatgct atcccaggaa atagaaatga
    28921 acagccagac aatggaagca caggattttt aagatatcaa gcttgtgata atagaacaaa
    28981 tagtttagga tattggctat gttttataga ttctagacaa agaaatatag ttaggtaaaa
    29041 ataataaaaa tgaaaaaatt tagactcaat tcttatttta ctgaaaaaat taatgaaatg
    29101 tagtacaaaa ctttaaaaac tattgataat atttaaatat tacactacaa tatatcttga
    29161 aatacctatt atattatgga ggaaaattat gataaacgag caaagaattt taaatgagtt
    29221 tcttgaatta gtacagatag atagtttatc tttaaaagag gggaatgttg ctaaagtatt
    29281 agttaaaaaa ttagaagaaa taggttgttc agtagtaata gacaatgctg gtgaaaaagc
    29341 aaatggagaa actggtaata taatagctac attaaaagga aataaagaag gaaagaaaat
    29401 attatttagt tcacatatgg atacagtaac tccaggtata ggggtaaaac ctatagtgga
    29461 tgaagcaaat ggaataataa aaagtgatgg tactacaata ttaggttctg atgataaagc
    29521 aggtatagca gctatattag aaggcttaag atatataaat gaaaataaca tagaacatac
    29581 tgatatacaa gttgtattct ctatatgtga ggaatgtgga ttagttggag ctaaaaattt
    29641 agactatgga aaaatagatt ctgaatatgc atttatatta gatagtggtg gttctccagg
    29701 tgaaataata gtaaaagctc ctgcacaaga tgtaataaat gttaagatat taggaaagac
    29761 tgctcatgca ggtcttgaac ctgaagctgg aataagtgct ataatggtag ctgccagagc
    29821 aatagaaaat atgaatttac ttagaataga cgaagaaaca actgctaaca taggaattat
    29881 aaacggtgga acagctacaa atatagtaac aggagaagtt aatatagttg cagaagccag
    29941 aagtctaaaa gaaaataaat tagatgttca aactaaacac atggtagaga cttttgaaaa
    30001 agctgcaaaa gattttggag ctcaaattga gatagatgtc aatagagcat atacaccaat
    30061 agatgttagt gaggattctg aaataataaa acttgcaaag aaggcttttt caaacttagg
    30121 tatagaaggt catactgaat ctacaggagg aggtagcgat acaaatatat taagtaagaa
    30181 tggtatcgaa gctataactt taggaattgg tatgaaaaat gctcatacac taagtgaaca
    30241 tatagctata aaagacttat atgactctgc taaaatggta gtggagataa taaaggaagc
    30301 ataaatttaa ataatagtgt ataatatata tatcgcctag cttaagctag gtgatttttc
    30361 attttataga agattgataa tctctattga aagcaaagag tatacatttg catataagag
    30421 agtgtttaat ttatgttcag atgtaggttc ttaataatat ttagattgtt tcataaggga
    30481 ggaataaata tggaaacaag gtatgaagaa gcaaataaaa taacaataca atcaatactt
    30541 tggaatgtag tattaacaat aattaaggtt atagctggtg ttattggtaa ttctagcgct
    30601 atgattgcag atggattaca ttcagcatca gatattataa gttctatagg agtactaata
    30661 ggcaattatg tatcttctag acctggagat agagagcaca attatggtca tgagaaagca
    30721 gagacattag tatcatttgt gttatcaata ttgcttattt tcgtttctat aacaataggt
    30781 atagaggcaa ttaaatcttt atttaactta gatgcattaa gtgttccatc aatattacca
    30841 ttagtagtat cagttatttc aatcctgata aaagagtatc aatatagaat aacaataaaa
    30901 gttgctaaaa agataaattc accagcctta aaagctgatg cttggcatca taggtcagat
    30961 gctttatctt cagtagctgc ttttataggt ataggtggtt ctattttagg gtttaagcca
    31021 ctagacccaa ttgcgtcaat tgtagtggct atatttgtag ctaaagtagg aattagtata
    31081 cttataagtt ctgttaatga attgatggat gtttcagttg acgaagaaga gataaaagaa
    31141 ttaaaattta ttgtagcaga tacagaaggt gttaaaaatc ttggtgatat aaagactaga
    31201 aaacatggag ctatggcata tgtagatttg actatatgtg tggatgaaaa tttgacagtt
    31261 aagcaaggtc atgatattgc taccaagctt gaaaaacata taataaaaca tatggaattt
    31321 gtaaaaggca taacagttca cgttgaacca tgtactaatt gccaaggaaa taagtgtaat
    31381 aattaattaa aacttaaaaa aaagtgtaaa aagttatata attgttttat gattataaac
    31441 tctaggggtg gttaaatgag caagaaaaga aaactaaaga aaaaagctgc aatattaata
    31501 ggagtagttg ttttctttat aatatacttt atatccttta gaataggaat aaatatggaa
    31561 aaggataaaa gtgaagtgcc aaagaaggta gaaaaagaag aagaagataa taggtcttta
    31621 aggactcaaa taaaagaaaa gaaaaaggtt tatatatcag acaaaaatat agaaaacata
    31681 aaaattgaag aagatatgtg ggatgaaata aagttatttt tctcagattt taagaaagta
    31741 agaaatacta cttcttctta cgaagcagtt tatgaaggtt attctgatga tggagttaaa
    31801 ttttctactg accttaactt ttttagagta tatactgtaa ataaagaaga atattataaa
    31861 gtaccagtta gttctaagga tgcttttaag aaacttttag atgagagtat atatacttca
    31921 tttgaccttt taagtcatta taaagattgg aaagaggtta ctataactca tggaaaagaa
    31981 attaaaaaag ttcatagatg gaaatttgat gatttagcac ataagatgat ttcaaagagg
    32041 gttgtaggaa aagttcaacc tgagaaaagt aaggaaagaa gtgactataa ttttactata
    32101 aatataaaag gtgataattt tgatgtaaaa gttgatacaa tgggaaaaga ttatgtaaaa
    32161 gttacttcta agaaaaatgt atcttactat gaggttcata caagtttatt tgattacctt
    32221 aaaaatgaga tatttgaaat tggaaagaaa taagacttta agaaggctat caaattagat
    32281 atttgatagc ctaaattatt tttatatatt atttttcaac caacaagtct gcaaccttat
    32341 aaattggacc agcaccagca gttattacta aatcattatc cttaacattt tcacgtaagt
    32401 attttactat atcttcaaat tcttttatat agatggcatc tacattgttt tgatataatt
    32461 tctcaaccaa gtccttagaa tgtatatctc cagggtcttt ttccctagca gcatatatat
    32521 ctgttatgat aactttatca gcagcataga atgcctctga aaattcacct aaaagagatt
    32581 ttgttctagt ataagtatgt ggctggaaga tacaccataa agttgatttt tttaattttt
    32641 tggcagcagc taaagttgct tttaactcag ttggatgatg tgcataatca tctactacta
    32701 aagcattctt ataataccct ttagtttcaa atcttcttcc gacaccttta taaattttta
    32761 tattttttct tatagtctct aagtcaatac cagaaacaag agctgccatt atagcagaag
    32821 aagcattgta tatgttatga agaccatata cagaaagttc aaattctcct aaatctcttc
    32881 cttcatattc tattctaaat attccatgac cactattgtc aaagtgaata tcttttatta
    32941 cagcatcatt gtcagaatct ctaccgtatt ttataatagt agctttaaca tcatacaata
    33001 tgtcatcaat attttcatca tcgccattta ttatgaaata gccttctggg ggtaataatt
    33061 ttccaaattt gttaaaagaa gccttgattt catctattcc agagaaataa tcaagatggt
    33121 cttcttcaac atttaaaact atagatatct ttgggttaaa attaaggaaa ctatctacat
    33181 attcacatgc ttcagttata aagtggttgg aattacctat cttaacatta ccacctatca
    33241 tacttaagtt accaccaact agtatagttg ggtctaagtc tgcatattca aagattgtag
    33301 ataacataga tgttgtagaa gtttttccat gtgttccaga aactgctata gaatttttat
    33361 attccctcat gatttggcct aaaaaagtcg ctctgttcat taccaattta tttttttctt
    33421 tagcagccac aagttcttca ttgtctggat gaactgctgc tgtataaaca accatattta
    33481 catcatctga tatattatct tttttctgac caatataaat agttgcccct tggtccctaa
    33541 gtttgtctaa taggtatgat tcgtttgaat ccgaacctga aacttgataa cctttattga
    33601 tacatatttc agctaatgca ctcatgctga taccgccaat tcctataaag tgtatattca
    33661 taataaaacc acctttcttt ttaattaagt cctacaatat gaactattta tgtggtataa
    33721 taatataatg ttcaatattt tataattaat atgcatataa tattatatgt attttatttt
    33781 tgaatataat aaaacataag taatattata ccacaataag aattgttatg cattagttag
    33841 tttaacgtta tataaaggta cttgtaggag gaaataataa tgaaatttaa aagaacagag
    33901 agaattggag caatagttaa aatactgtct gataatccaa ataaaatata tacattaagt
    33961 tattttacaa atcaatttaa tgcagcaaaa tcaacaataa gtgaagattt attagttgta
    34021 aaaaatgtat ttgagaagct acatttaggt aaagttataa ctatctcagg agcagcagga
    34081 ggagtaaaat atatacctaa aacttctata gcagaaaatg cagagttctt aatggaatta
    34141 tgtgagagaa tatgtgacaa gtctagaata ctatctggtg gttttttata cttgattgac
    34201 ctaatttatg accctacaat agctgctaag ataggaaaga tattcgcatc aaatattgag
    34261 tatgtagatg cagattatgt tgtgacaatg gaaacaaaag gtatacctat ggcacttatg
    34321 actgcaaaag ctatgaattt acctctagtt ataataagaa aagatataaa ggtatcagaa
    34381 ggtcctacac ttagcatgac atatgtgagt ggaaacagct ctaaagttga aagtatgagt
    34441 ttgccaagaa aagctcttaa accagatagt aaagttataa ttatagatga tttcatgagg
    34501 ggtggaggta ctataaaagg aatggtagac cttatgaatg aatttggtgc agaggttata
    34561 ggtactggag tattcatatc tacaacgaat ccttcagaaa aaatggtaaa agattatatt
    34621 tcattgattc aattggatgt taatggagat aaaatagtag tagaaccaaa cttaaagact
    34681 tttaaagatg aatatagaaa tgaagattta gacgaagaag aagattcaga atttgaattt
    34741 gagatagatg aagattaata aaaaaaatat ttagaaaaat atgtaaaaat aaaaagagga
    34801 tatccctagt tgttcataga attatttaaa aaacagttta tattaattta ttccagcgat
    34861 aataatttta atataaatta atttctgtca aaatcaaagg gggatatttt ggtatgaaga
    34921 taactgacgt aagagtaaga aaattaacag aagaaggtaa gatgaaatgt atagtttcaa
    34981 taactttcga taatttgttt gtagtgcatg atataaaagt tatagaaggc cataatgggc
    35041 tatttatagc aatgcctagc agaaaagtag gcgaaggaaa tttcagagat atagctcatc
    35101 caataaatgc agaaatgaga caagttttag aagatgcagt tttacaagca tatcatgaag
    35161 cattagttca atgggaagta gctgctgaat aataaatata taaaatggag agagcccgaa
    35221 catttaggct ctttttaaat gtagaatttc tattaaaata tgtacttttt agtaaaaaag
    35281 tgctatatta ttagtgataa tgtatatgtt gtatacaaat tgttagataa atgtattata
    35341 atgtatattg attaagagaa taatacgaat aaaattaaat tagattgaat ggagtgtatc
    35401 aatgaacttt aaagctataa tccttgctgc tggcaaagga acaagaatga agtctaaata
    35461 cccaaaagtt atacataaag tatgtggaaa agaaatggtt aaccatatta tagatgtttc
    35521 aaaaaaatca ggggtaaaag atactgtcgt gattttagga catgaagctg aggtagttaa
    35581 agaaaagctt gcagaagaaa ttataatagc catgcaaaca gaacaacttg ggacaggaca
    35641 tgctgtaaag atggctaaag aatatattaa tgatgaagat acaatagttg tactttgtgg
    35701 agatactcca cttataaaag aagagacact gaagagatta tttgaatatc atatagaaaa
    35761 taaatatcat gctacagttc ttacaacaag agttggaaat ccaacaggtt atggtagaat
    35821 aataagagat aagaagggtg accttcttaa aatagtggaa caaaaagatg caaattcaga
    35881 agaaaagatg ataagtgaga taaactctgg aatttattgt tttaatggaa agagtcttag
    35941 agaagcacta gatttgctaa ataataacaa ttcacaaggt gaatattatt taactgatac
    36001 tgctaaaata atgagagata aaggattaaa agttggtgca tttgcaggtt caactattga
    36061 agaacttatg ggcgttaatt caagagtaga attatcaaag gcagaagaaa ttatgagacg
    36121 aagaataaat gaatctcata tggtaaatgg agtaactata atagacacta actctaccta
    36181 tatagaatct gatgttatga taggcaatga tactataata tatccaggtg ttatgttaca
    36241 agggaaaaca aggataggtt cagattgtat aattggaatg aactcatcta taacaaattc
    36301 agaaataggt gatggtacag aaataaaaaa ttcaactata attgatagta aggttggaga
    36361 aaattctaat gttgggccat atgcatactt aagaccaaag agtgacttag gaaataatgt
    36421 aaaaataggc gattttgtag aagtaaaaaa tgctattata gaagatggat caaaagcatc
    36481 tcacctttct tatataggag atgcacatgt cggtaaaaat gtaaatattg gatgtggagt
    36541 agtatttgta aactatgatg gtaaaaataa atttaaatca gtagtaaaag acaatgcgtt
    36601 tataggttca aattctaatt tagttgcacc agtagttgta gaagaaaaag gatatatagc
    36661 aacaggttca acaataacac atgatgtccc agatggtgct ttggcaatag caagagaaag
    36721 acaagttatc aaagaaggat gggtagaaaa aaagaatcaa aaagacgacc aaagtaagta
    36781 attatgtagt ttattatttt ggctaaaaaa tttagctcga aattattata aattatattc
    36841 attagtattt taaaattttc aggagggtta cataaatgaa tactagcgga agcgagatta
    36901 aaattattgc aggtaattca tcgaaagagt tagcacaaaa aatagctgac tatataggtg
    36961 tatcagtact agattgtgaa gtaggtacat ttagtgatgg tgaaatatgt gtaaacatga
    37021 atgagacagt aagaggttgt gatgtgtttg tagtgcaatc tactaacagc ccagtaaatg
    37081 ataacttaat ggagttatta atcttaattg atgcgttaaa gagagcatca gcaggtagaa
    37141 taacagcagt cattccttac tatggatatg caagacaaga cagaaaggct aaggcaagag
    37201 atccaatcac tgctaaatta gttgcaaatt taataactgc tgctggagca gacagagtat
    37261 taacaatgga tttacatgca gctcaaatac aaggatattt tgatatacca ttagaccact
    37321 tactaggtgg aacaatatta gcaaattatt ttaatgaaaa gaaaatagaa gatttggtag
    37381 tagtatctcc tgacttagga agtgttacta gatcaagaaa atttgctaat actttaaatg
    37441 gagaagttcc aatagctata atagataaaa gaagaccgaa agctaatgta tgcgaagtta
    37501 tgaacttaat aggtgatgtt aaaggtaaaa atgttatact attagacgat atgatagata
    37561 cagcaggaac aatagttaat gctgcaaatg cacttaaaga gtttggagca aaagatgttt
    37621 atgcttgttg tactcatggt gtgttatcag gtccagctat tgaaagaatt gctaattcag
    37681 aaataagtga gttaatagtt cttgatacta tacaacttcc tgaagagaaa agaatagata
    37741 agataaagat aaaaacagta gctcctttat ttggagatgc tataagaatg atattctcta
    37801 atgaatcagt aagtaaatta ttctaattta ttgtatttat gagagttgtt taaaaggata
    37861 taaacctttt gagcaactct tttttgattt tatacttatg gaatgttatt tttttcttgt
    37921 tagaaaggta tatattattg taaaaagaga ttatagttta aaattatgta tatttaagta
    37981 aaataaactt aataaagggc atattattca aaatattatg aatataaaaa atattacaaa
    38041 aaagtattga aaaaattcag attatgtagt attatgtaaa tataaataaa gaaagaggtg
    38101 tttccaatgg gaaggttaga agatgaaccc ctaataatta aatgattcag tcacaatcta
    38161 aagtgaatat aaaaatctat tgaaagttta tttataagaa ttgaaaatag tatctattct
    38221 atctttagtg tttgtgagag ggttctggat tatataagat tactgtaaag agtaattttg
    38281 cacaataagc atagctgtaa atgaagagtt tcgtttatat aatgattgtg gctgaatcat
    38341 aactataata gatagaatgt ttataataga tgattttata aaatactata ttgtaatagc
    38401 ttttagcttt caaataaata ttagcaaagg atggaaatga caatgataaa actaaatgat
    38461 aatttataaa tatctcctta cgatatataa taattgtagg gagatgtttc ttttttttgt
    38521 agagtataat ttttctagaa attctgtttc aatatgtaaa aagttggtat atataaatag
    38581 tataaacagt gttgctaaaa tatggtagat attatataat ataagtggat atgtatatac
    38641 attatgagtt atataatttt gaatttaata aaatagaaac gttgatttat gttctgtaat
    38701 gtgggcacct tagagcatat tgagttagtg gtgcaaccgg ctatgaaatt gtatttattt
    38761 atagatacta tcattttcat agcttttttt atttaaaaaa tggttatgtg ttagaaataa
    38821 atttggttag tacgtttaaa taattttact tagattttta accagatata ttataagtaa
    38881 gtattaatta aaaaatttaa gggggaataa aaatgaagtt aaaaaagaat aaaaaaggtt
    38941 tcactttagt ggaattattg gtagtaattg caattatagg tatattagca gtagtggcag
    39001 ttccagcttt atttagtaat ataaacaagg ctaaggtagc aagtgttgag tctgattata
    39061 gttcagttaa gagtgcagca ttatcttatt attcagatac taataagata ccagttacac
    39121 cagatggtca aactggttta agtgttttag agacttatat ggagtctctg cctgataaag
    39181 ctgatatagg tggaaaatat aaattgatta aagttggtaa taaattggta ttacagatag
    39241 gtacaaatga tgaaggagtt acattaacag aagcacaatc agcaaaatta ttgagtgata
    39301 taggtgaaaa taaaatatat acaagtgtta cagcagataa tttgggaaat ccattaacaa
    39361 gtaatacaaa agtagataat aaagttctat atatagtact tatagataat actgtgatgg
    39421 actcaacaaa atagttaaaa ctatattttt ataaaaatat tgtaaattta atgaaaaata
    39481 taatataaaa gacaggaaga aaatcttcct gtttttttat actattttct ttaatgttca
    39541 attatgaatg atgatataat tgagatagta aaggagtgaa acctgtggct aaaaaagtta
    39601 gaataggaga caaactggtc gaaaaaggat atataacaga agaccagctt aaatgggcac
    39661 tatcagaaca aaaaaacagt ggaaaaagac taggagaatt tctagtacaa gaagggctta
    39721 tagatagtaa cttactaata agtgtattaa aagaactctt ggatatagaa agtatatttt
    39781 tagaagggac agaaatagac actttagcta caaagatggt tccagaaaat atatgcaaaa
    39841 gatatactgt atttccattt aaaattgatg gaaataaaat atgtctagcc atgtcagacc
    39901 cacaagacag agaagcagtt caagatgtaa ggcgtatgtc tggtaaagac gtagagatat
    39961 ttatatcaag tacagaagat ataaacaaag caataggtca tgcttatgca cattcagaaa
    40021 taaataaggc aatgactgag tacaacaaaa atagaactgg tggagtaaga gaaacagtaa
    40081 tacttgaaga agatgtaaat gctgctccaa tagtacgatt agtaaataac atactagaaa
    40141 atgctgttag aatggaagca agtgatatac atatagaaca aagtgaaaat tacatgcgtg
    40201 ttaggtttag gatagatgga atgttaagag aatatatgag gatgaactca gcaccatata
    40261 aggcagtaat cagccgtatc aagataatgt cagatataaa tatatctgaa aagagaatac
    40321 cacaggatgg tagaatctat ttaaaagtag ataataaacc catagatttt agggtttcta
    40381 caatgccaac taacagggat gaaaagatag ctatgagggt tcttgataag agtaatttta
    40441 tggttagtaa agaagtacta ggaatagacg aacatggctc taagatatat gatgaattga
    40501 taaacactcc ttatggtctt atattggttg ttggtcctac tggaagtggg aaaaccacta
    40561 cattgtattc aatgttaaat caactaaata cagaaaatag aaatctatta acaatagaag
    40621 accctataga gtatgaatta cctggtgtaa atcaatctca aataaatgaa aaggcagggc
    40681 ttactttcgc cagcggactt agagctttta tgcgtcaaga cccagatata ataatggttg
    40741 gagagataag agatactgag acagcagaaa tagcaattag agcttctctt acaggacatt
    40801 tagttttaag tacattacat gcaaatacag cagttggagc aatttcacgt cttttagata
    40861 tggatgtgga aagtttttta ataacttcat ctgttttagg tgtaatatct caaagactta
    40921 cacgaaaaat atgtgagcat tgtaaggttt catatgaagc agatattgga gaaaaaaagg
    40981 ctcttggtat tgatgtaaat gaatcagtaa ctatttatag aggaaaaggt tgtgaaaggt
    41041 gtaataatac tggatataaa ggacgtctag gtatatttga aatgcttgaa attactccag
    41101 aaataaaaga gttaatagat tcatctgcaa atcaaagaga aattttaaag atggctagaa
    41161 aacaaggcat ggttagctta aaagaggata tagttaaaaa ggttttaaat ggaaagacaa
    41221 cagtagaaga aatgattaga ataattttga tgactgatta aaggatgata ttatgaaaag
    41281 ttttaaatac acagtaataa aagaggacgg aaaaaagcaa actgatgtga ttgaagccaa
    41341 cgattttaat gaagctagaa atcttcttag aaagagaaat cttagagtta ttgaaatcaa
    41401 agaaagcaaa aataaaaata taagattatc tagtagaaag agaaaaaaag acttgggagc
    41461 tgaccagata agccactttt gtagacagtt tgctattata gtatcttctg gtataaatag
    41521 tatttcagga ttagaaacat tagctagaag gtcaactaac attacattaa gagaagaaat
    41581 taatcgtata gtggcagaaa taaaagtagg ttctactatt gcagattcaa tgctttcatc
    41641 aaaatcaaag tttccaaagt tacttggtgc tatggtagct acaggtgaag ctacaggtaa
    41701 attagatgaa gtattaaaaa gtatggcttc attttatgca agtgaacaca gggttaaaca
    41761 aaagcttaga aatgctgcaa catatccatt aatagttttg atttcttcat ttataatgat
    41821 ttttatattt acaacattta tggtgcctaa gatgattaat tcaattacaa cagtaggagc
    41881 aactcttcca cttataacaa gaattgttat ggggtttggt atgtttatga agaagttttg
    41941 gataatagta cttttagtta ttatattatt tatctatcag tttaaaaaat atttaaaaac
    42001 gtcagttgga agggctcata aagatagagt tataaacaag atacctgttt taggaaaagg
    42061 aataaattgt atggtagcta cacgattttc aagagcattg tatctatttg tatcaacagg
    42121 atacccatta gttcaagggc ttgattatat tatagatagt gtaaataaca ccatggcaga
    42181 gaagatttta gcatcagcta aagatggaat aacaagagga gaaggcttag cagaaaattt
    42241 agagagatat acgtattttg actctgtgtt ggtacagatg atagctatag gggagcagac
    42301 aggggaatta gagaatataa gtagacagat ggcagaattt tatgagtatg aatccgagat
    42361 ttatttaaat aggatggcct caatgataga gcctgtttta ataattgcag ttggtattat
    42421 agttgcgata ctggttgtat caatatttat gccaatgctt agtatatatg atgccatgta
    42481 ggagggaaag gacaaatgaa taaggtttat gtatcatatt atggcgattc tatttccata
    42541 gttgagggca gatataaaca cgataaggat aagttttatg taaaaaattt taatgtgttt
    42601 tcaatagagg atattgcaca agatttttct aaggaaaagt atgctctatt gagatacgca
    42661 ttagaaaatg ttaagttaaa atcaagacat gtagtttttt gtttaaatac aagagatgta
    42721 attttaaaac cccaaaaact tcctaatatg gacaaaaagg atttagatgg atttatgaag
    42781 ctagagatgg acgaaatgat ggctttggag tcagatgaat atgtattttc gtatgaagta
    42841 tctagtgaaa cacatgataa ttcagatggc gatgaatcaa gcttaaatct tatcattgga
    42901 gctatacaaa aggaagaggt aaatgcaatt gtagagataa tgcatgaatt tgatttagta
    42961 ttagatagaa tagatacatt atcaacagct tacttaagaa tgcttaaaaa tttagactac
    43021 aatgatataa tggtaaccaa tataagtgac aatagtacaa ttataaatat atataagaaa
    43081 gatactttat ttattagtga taatatacct ataaagataa ctgctaaaga tatggacatg
    43141 caattattaa atgtagtaga agaatcaaaa ggtcttatga attactattc gtcaagaaac
    43201 tttggtaagg ttacggatac tatattaata ttaggaaaaa gatattccaa taaattaatt
    43261 tatgaaactt ttagctctgc attttcaagc tatgtttctc aaggccttac tgagataatg
    43321 gatatatctg atatgataac tggagatata gatgaagatg atataaattc aattgtagag
    43381 cttttaggaa gtatgataga acctaaaggg aaaagagatt ttgaaaatat aaacttttta
    43441 ccaatggata tacttagaaa acagataaaa gctaaacaaa tgaaaaacat actgaaaatt
    43501 gctccaatag ttattttgat tcttgctata ccttatttat gtttaatttt ttcaaataat
    43561 ttagcaaata aggaacttga aaatgttaat ggtgaaataa gaaatattga atctgcatat
    43621 tatcagattg gaaatataga aaaaatgata cagagtaaaa gcgaagaaat aaaggtatat
    43681 gatatgttaa ttgggaaaaa ggtaaagtgg gaaaatttat tggatgatat agataaaaat
    43741 actccaagta aagttgaact aacaagttta tcaacaactt atcaaaatct tggaactaat
    43801 aataaagctg ataattcaaa aagtaataag actacaacag ataaatcaag taacaatgaa
    43861 acaaaatcaa gtacgaaaag tgatagtaat ggagataaaa cagataatga tttaaatgaa
    43921 gataagacta caaatgtgtc agaagcatta actggaaata gtgagactaa tagtaataac
    43981 acggataaag atgataaaac tccattgtat gataagatac caaatgttat aaatatagaa
    44041 ggaaatgcta aagattcctc ttatgtaggt caatttttat ataaattaaa gggattatac
    44101 tatttcaagg atgttaaatt acatagcata aaaagtaatg cagaagattc taactataca
    44161 tttagtatga cattatacct gaaagaaggt gtattaacta atgaataaag atatatttaa
    44221 aaaagatata aaagatatat ttaaaatgga agttagtcta aaagggattc ttataaaggt
    44281 tataatttta ttagctattt tatcatatgg ttattttgga ctttaccctc aatatcagaa
    44341 atatattgct acaaaaaatt ctgtaaaaca ggctactgaa aaattaaata tatataaaga
    44401 gaaaactgca cttatgccaa aatatgaaaa acaacttgaa gaagttgaaa gtgaattaaa
    44461 agaaaaaagc aaaaatcttt tatatgatat gcaagatggt ctttttttaa taggtttaga
    44521 taaaaaaatg aaggcttata atattgactt aactagttat gacgttggaa atgttaaaga
    44581 atacgaacat ttttatggta tatcaacaac aataagtgtt agaggtgatt atagaaatgt
    44641 caaaaaatta atggcttatt tagaagaaca aaaaaatgtt actcaaatac tagattatac
    44701 aatgacttca tatatagaac cagaaaaaga agaggaagaa acaacaaaca ataaggattt
    44761 aattaaaaat gtgaacataa ataaagatac aaaaatatac tgggtggaag gcgaaaataa
    44821 gtggcattta tataaggatt gtccattgat aaaagaagga gagattctaa aaaatgacaa
    44881 acttttagat aggtctacta attatctatg taatacttgt gtacttagag ctgcaacaga
    44941 aaaagaagca aaaaaagaag tcgtagctcc aaaggcagaa ggtgtagtag atgctacatt
    45001 taaatttata atgtacacta aagagaatac tacaatgata cttgatacag ataatccatc
    45061 ttcatggaga ccaggaaaat ataatccatt taagtctagt gctaaataaa gctaagtaag
    45121 ctttaaagat aggtgatgag tttgtacaaa aataatgaaa aaggtcttac tttattagaa
    45181 gtaataatag ctgtttttat actgacaata gttttaagta tttcttataa agtgttcaat
    45241 ggtataacat cagcagtaaa aaagcaacag attattacag atgctcaagt aaatattaat
    45301 ctaattaata agtatctaaa tagagatttg gaaaactgta aagagctaac taaaactggt
    45361 tcaggtaata attatgaata caatatagag atgccagata atgttgtaaa atatgaagtt
    45421 tctatagaaa ctaaaaaaaa tacagaggta tattctgtaa cgagaatcca aaacaataca
    45481 attgatacag aaaatgaagt tagagaagag ataatctata atcaaccact agttcaaaac
    45541 aataaagaaa tgaaggaaac accatttaaa atagaaaagc aaactggtaa atctatttat
    45601 actgtaagta tatactataa tgaatcagtg caagaaagtc ataaaaatag caatttaaat
    45661 aacaaaactt atacatttga tgttatgtca agaatagggt aataagaatt tattaaaaaa
    45721 taagtaggtt gataaaatat gagtaaaaag aatagtgaaa gaggattttc cttaattgaa
    45781 gtgttagtag ctatggctat tatgggaatt gtactatttg cattttttaa tattatcaat
    45841 actaataaca aagcaaacac taaaaatgac acagatataa cttccttaaa ctatgtccaa
    45901 agtgaaatag aaaatctaag agaaaagata aaaagtggag aatttgattt tgatagttta
    45961 gataaactag aagatggaac tgtcgtatat gaaaaattaa tagataaatc aaaaaaagtt
    46021 gtatatgata aagttcttag tgaaggtgac gtgagcttat atgatactcc atatgaaaag
    46081 attacaacaa taaaagatga agatggtaat ttaatcgaca aaggaaatat tacaaataag
    46141 ataaagacta ttgtagaaga taaaagtggt cagatatata aaatagctgt aactgggaaa
    46201 agcatgaatg actattcaag taaaaaagag gttaaaattg taactgaaat atttaaagat
    46261 aaataatttt acttgggggt gagattttga ggaagtggaa taaatttaaa agtgaaagag
    46321 gggcagcttt agttttagtt ttgattgtag tagcattgct ttctattgtt ggattgatat
    46381 tttcaaatca gatagctaat agaataaaat ctacaaagac tactaatgaa ggtatacaag
    46441 caaagtattt agcagagaca tgtgtggaaa atagtattga taaagcatat gaaaaattgt
    46501 atgatgagct tgagaaaatg gataatgagt ttaaaagtga aaatcaagaa aaatccatat
    46561 ctaggtcaaa attaagaaat atatcagatg aagattttaa taatcaagat gagaaaaata
    46621 ttgaagcaga aagacttgga tatatgaata atataaattt ctatttaaat aaagcttctt
    46681 cagacttgga aaaagctagt atggaattga aaaagctata tgatttagat atgttggact
    46741 atagagacat tgaatatgta gatgcaaata ttatttcaca tagagattct atcttagaaa
    46801 tttgcaagaa ttatacttct ggagatatta gtaaaataaa tgaatatatt ctgaaagaag
    46861 atatagactc aactacattg attgaggcaa agttagtgaa taatgatatt cttttgaaaa
    46921 tgtttttaga agaaaataaa attgaaaatg aacatttaaa ttcagccttt tcacatactt
    46981 ataaggcatt agataacatt tctttggcga tgcaaaatat gattgagtat agacatacgt
    47041 ttcatataga tgagccaaaa gtagaagtat ctaatgggat tccagattct caacaatatt
    47101 atgaactaat acaaaatcct ataataaata gtatggagta tatctggaat agtaaatggg
    47161 atacattaga aaacctattg gaaattttac caaatcaaac tcaaggattt aattctttaa
    47221 gagttcattt gagaaataat gtaagaaaat ttgagaagtt aagcgataat atatctagtg
    47281 gtaaaaaaaa tacagcaaaa aattttttaa agtataaaga gttattgtat gaaatatcag
    47341 accaatgtaa tcaactaaaa agtatgtctt atgagaaaat acctgttaaa tatgataata
    47401 tggctttgat aacaactttt gactatatac aaaatgagct tttagcagag ataaaatgca
    47461 gattaaaaga attaaaacca caagaaattg ataaaacaga aggtattact ataaaaatac
    47521 ctttttataa ggctgactac gacatgacaa aagaaggatg gcctaaatta aaagaaaatg
    47581 gttcaggggc ggagttaagc ttaatggtaa ctggtgataa agatggaata aaagaagtag
    47641 aagttacaga tggtaaaaaa aatattattg gtttaggtgt tgaagaaaat tcaaattcaa
    47701 agtataaggt tgacgccatt gtaaacttta atctaaatat agatacaaat gtagttggaa
    47761 attatgatat aaaagataaa attttgatta atcatgatat aagttcatac aaaaaagtaa
    47821 actaaatata agaagcaact tagtataaat aaataataaa ataattttat tatttactac
    47881 taaaaaaata agtaaactaa tagaagatat ggagagtaaa tattatgtat atttatgatt
    47941 tattagagca aggtataaga ctaaacgcat cagatataca cataacagtt ggaacaaatc
    48001 ctgtagctag agtaaaaggt ggatttgtaa aactaagtga acaaatattg acatcagaag
    48061 taacaatgca aatggcaaaa gacatagcgg gggaatctat ttttaaagta atagaagaac
    48121 atggagaagc tgatttttca gcttctctaa aaacaggaga aagatttagg gtaaatgcat
    48181 ataggcaaaa aggaaattac gcaatagcaa taaggactat aacagcagaa attccaacat
    48241 ttgaaaaatt aggccttcca gagagtataa aatcttttac tgaaaagcat aaaggattag
    48301 ttttagttac aggtccaaca ggaagtggta aaagtacaac acttgcaagt atgataaata
    48361 taataaatga aaaacaacaa aaacatataa ttacacttga agacccgata gaatatgtac
    48421 atcatcataa acaaagttta gtaaatcaaa gagaagtagg aactgataca gaaagttttc
    48481 attcagccct tagagctatt ttgcgtcagg acccagatgt aatactaata ggagagatga
    48541 gagaccctga aactgtttca atagcattaa cagcagcaga aacaggtcat ttagtatttt
    48601 caacactaca tacagtaggg gcagctaaga caattgatag aatagtagac atgtttcaac
    48661 catcccaaca gcaacaaata aaaacacagt tatctacagt ttgtgaaggt gtggtatcac
    48721 agcagttact tcctacagca gatgggaaag gcagaatagc agcaattgaa ttgatgtttg
    48781 ctactccagc aataaaaaac ttgataaggg aaggcaaaac atatcaaatt ccaaacatga
    48841 tacaaactgg agttaaagta ggtatgaaaa ctatggacca agatttaatg gaactttata
    48901 aaaatggaaa gattacaaaa gatatggcac ttagtaggtg tactgaccaa gagtttatga
    48961 caagaatgat aggtggagta aactacaatg gatattataa tcgttaatct atatgtattt
    49021 atagtgggta tagtgtttgg aagtttcttt aacgtctgta tttttaggat tccagaaggt
    49081 atatctattt ctagacctcc ttcccattgt atgagttgta atactagact aaagccaata
    49141 gacttaatac cagtgctaag ctatttgatg agtggcagaa agtgtagata ttgttatgag
    49201 aaaatttcta gtagatatgc tatagtggaa ttaattacag gaattttatt tttaacagta
    49261 tttatgttat atggaatatc tacatcaact atttattatt tggttcttgt gtctttactg
    49321 attataatta catttataga tattgaccac tttataatac cagataaaat attgattttt
    49381 ggagctatat tttctatgat ttttaacctt ttatttaaag aaattccagt taaggattca
    49441 attctaggtg tttttatttg tggaggaagt gtctggatta tagttctttt gattgaattt
    49501 gtaataaaaa aagagtgtat gggtggagga gatatcaaac tatttgcaat gctaggcctt
    49561 tacatgggtg ttaaaaatgg tcttttgaca gccttactaa gcgtttatgt aggagcagtc
    49621 tatggaatct gtgtaataat tataagtaga ataaaaggaa aggaatataa ttctgttata
    49681 ccatatggac cttttatatc tattggagca ttaataacaa tcttatgtgg aaagcaatta
    49741 cttgaacttt atttttctat ggttatatag atgatagtca agttaaataa agttttaatt
    49801 taaaaaaatg aattaaagta tttaataagg acaatattat tattaaccct attactaaag
    49861 tgctacaaac tatggagtat ataataataa tttccttatt ttttgcacat ttgataaata
    49921 aatctctatg tgttttttgt gatagagaaa agaaaaattt atataatacg ttttttattt
    49981 acataataac tgtagtttta tctgtattaa tatatctaaa atttgggatt agtgtagaat
    50041 gtgtacaata tatggtttta attccatttt taataattat atccattgta gattactaca
    50101 caatatatgt atatgatata acaatagtta gtggtataat agttcaaggt ataatttttt
    50161 tggccttttt caatatagct caatttgatt atataaatca tatatttgga ctattgatag
    50221 gctttattat accttatatt attgctaaac taacaaaagg attaggctat ggagatgtag
    50281 gtctctatag cttatgttgc tttgcattgg gaaataatta tgggttttat gtgatagttt
    50341 tatcatttat tttagcgttt ttgtttttta ttattttata cataactaaa atatttaaag
    50401 atgtagatat aagaaagcaa attcctttta caccttttat ttccttgtca acaattttaa
    50461 taatatttac agagtataat atatttaatt tttattataa tttgttatac aaatttatat
    50521 aacaggaggt aagaaatgta cgtagtagta gggttaggta atccaggaaa gaagtatgag
    50581 aagactagac ataacgttgg atttgatgtt atagatattc ttgctaaaga atacaatatt
    50641 agtgttacta aaataaagca taaagctttg attggtgaag ggagagtagg tactgaaaaa
    50701 gtattattag ttaaaccaca aacttatatg aatttaagtg gagaaacatt aatagatata
    50761 tataaatatt ataaggttga tttaagtaat atagtagtag tatatgatga tatagattta
    50821 gaagttggaa agatacgtat aagaaaaaaa ggaagtggag gaactcataa tggcatgaaa
    50881 tctataacta agtgcctagg ttcaaatgac tttccaagag tgagagtagg tgtatctaaa
    50941 ccagaagctg gtcaagactt agcagacttt gtactttcta gatttagaaa agaagaatct
    51001 gataacataa atgaagcatt agaaaaagcg gcagatgcta ttgactcaat aataagagaa
    51061 aatatagata tgtctatgaa caaatataat ggatagtgag agggagattt aaatgaatga
    51121 tgttttttta tatcctttgc aaaattcaaa agagtataaa gatataataa actgtataaa
    51181 aaatacaaaa ggctcattat tggttaatgg acttttacca gtacaaaaac ctcatatatc
    51241 gtattctata tttaatgatt tatcacgaca aatgattttt ataacgagta gtgatttaga
    51301 agcaaagaaa gtatacgaag atttaagttt ttatatggaa gataaagttg aatatttagg
    51361 ttttcaagat atttattttt atcacttgga tgcaaaggac agaaacgaag aagcaaagaa
    51421 attaaaagta ttgttaaaac tagcaaataa agaaaaaatc attttagtaa cttctattga
    51481 ggcagtttta agaaaataca taccaaaaca agttttgctc gatagtgtat ctcattataa
    51541 ggtgggagat agcttagact tagaaaagtt aactgagaaa ttagtttcat tgggatatga
    51601 aagagtttca aaaatagagg ggtttggtca atttagtata agaggtggaa ttattgatgt
    51661 attttcactt gaatatacaa atccaattcg tatggaatta tttgatgatg agatagattc
    51721 catacgaact tttgacgtat attcacaaaa atcaattgat aaattgcaac aattctctat
    51781 aactccatct agagaattta tttatcccga aaaaactaca gatgcattag ttaaattaaa
    51841 aaaagaaaca actaaaaata ctgatgaagg tacatttcaa aatatagatt atatatcaag
    51901 taagacttat tttgaaggtg cagagaacta tatagattat atttatccag aagaaaacaa
    51961 aagtatattt acttatttag cagatgatgc aatagtattt attaatgata taacgagact
    52021 taaagaaaga tgcgaaaatt atataaatga gtttagagaa aattataaat taaatcttga
    52081 aagaggtctg gctattaaaa accaaggtaa attgttatat cactatacag atttagagta
    52141 cttagtaaaa gacaagtctg tggtattaaa ctcgctattg ccaaagtcta taaataactt
    52201 ttctataaaa tctataataa attttgaaag tagagaagtt cctacattta atggaaaggt
    52261 agatttgctt gtagaagaat taaatcggct gaaatataat ggatacaaaa taattttagc
    52321 aacaaatacc ttagaaagag caaataaatt aggaaaagat ttattggaca aaggcttaga
    52381 aacgaccatt tctaaagata gagatattga aattaaatct tcacaagtta taattgtacc
    52441 tgcacacata aacagtggtt ttcagtataa atctataaag tttgttgtta taacagataa
    52501 cgaaatgata ggtgtttata aaagagcgtc taagactagc aataaaaaag ttaaaaaagg
    52561 aaagaaaata gaatcctttt tagatttaag tgttggagac tatgtagttc atgaaaatag
    52621 tggtgtaggt agatacacag ggattgaaca aattacagtc aatgctatta aaaaagatta
    52681 tatgaaaata gtatatcaag gtggagataa tctatatgtg ccaatagacc agatggacaa
    52741 agtacaaaaa tatattggtg cagaagtaga aaaagttaag ttaaataagc ttggaacaaa
    52801 tgagtggacg aaagcaaaag caaaagttaa aaaagaaatt gaagatatga caaaagactt
    52861 gattgagctt tatgcaaaac gtgaaaaaat acaagggtat aagttttcaa aagatacacc
    52921 ttggcaggca gagtttgaat cgttgtttcc atatcaagaa acagaagacc aattaaaggc
    52981 tatagaagaa actaaaaaag atatggaatc aagtaaggta atggataggc tagtatgtgg
    53041 agatgttggt tatggaaaaa cagaggtagc tattagaagt atttttaaag cttgtatgga
    53101 ccaaaaacaa gttgctgtat tggttccaac aacaatattg gcccaacaac attataatac
    53161 attcaaagag aggtttgaaa attatccttt gagagtagaa gttttaagta ggtttaaaac
    53221 accaaaacaa caaaaacaga ttattgaaga tgctaaaaaa ggattagtag atattttaat
    53281 tggaacacat agaataatat ccaaagatat aaatttacca aacttaggtc ttgtagtcat
    53341 tgatgaagaa caaagatttg gagtaaaaca taaagaagct ttaaagaaaa ttaaatctac
    53401 agtagatgta cttacacttt cagcaactcc tataccaaga acattacata tgtctttaag
    53461 tggaataaga gacatgagtg ttatagaaga acctccacaa gaaagacatc ctgtaataac
    53521 atatgttaca gagagtaagg aaagcgtaat tcaagatgag atagagagag aattaagtag
    53581 aggtggacag gtattttttg tatacaatag agttgaacac attgaagaaa tggcaagtat
    53641 gattcaaaaa ctcgtaccag atgctagagt ggctgttgca catggaagaa tgacttctaa
    53701 atcattagaa aatataatcc taggattttt aaataaagat tatgatgtac tagtctgtac
    53761 tacaataatt gaaactggta tggacatatc aaatgcaaat acaatgatta tatatgatgc
    53821 agataaaatg ggattggctc aactttacca attgagaggt agggttggaa gaagttcaag
    53881 acaaggatat gcatatcttt tgtatgaaaa agataaaact ttaagtgaga tagcggagaa
    53941 gagattaaaa gctatcagag aatttacaga gtttggttct ggttttaaaa tagcaatgag
    54001 agacctcgaa ataagaggag caggaaatat tttaggttct caacaacatg gtcatatggc
    54061 agttataggt tatgatttgt acgttaaaat gcttaatgat gcaattaaaa aagtcaaagg
    54121 tgaacctatt gtggaggaaa ttgatgttga aatagattta agtgtaaatg catacattcc
    54181 agataattat atcaaagatg agttgattaa aattgaaatg tataagaaaa tagcttctat
    54241 tgaaaacaaa gaagacatgt tggatataca agaagaactt gaggatagat tctctgatat
    54301 acctaaacca gtccagacac ttcttacaat agcttatata aaatcgttat gtaagatatt
    54361 aaaaatagaa aagataagac aattaaaaga tgaaatatta ttagttccaa taacaaagta
    54421 tagaactaaa cagaaaatag gttataatat agttacagaa ttagaagaat tattagaaaa
    54481 gatgtgcaag gtaaaataac ttgtaaattt aagaagggat gttttaaatt tgaaaaaagt
    54541 aataacattg gtaatagcta tgattttggt agtatctgtg actgcttgca gttctagtaa
    54601 aggagaaact gtggcaacag ttgaaggtac aaagatatca tcagatgaat ttaaaaaaac
    54661 tatagctctt tataaagatt ctatggaaca aacttatgga aaagatatat gggataagga
    54721 agttgaaaag ggtgtaaaat acaaggacaa gtttaaagat ttaattcttg accaacttat
    54781 aactacagaa gtaatatatt ctcaagctaa aaaagataac ttacttccta aaaaagagga
    54841 tgttgaaaaa agttttaaag aattaaaaga cgctatgggt aaagatgaaa aatataaaga
    54901 acaacttaag aaattaggta tagatgatga gtttttaaga gaccaacaag agaaagattt
    54961 agcaatgcaa aactatcaaa gtaactttgc taaaaagact aaaatatcag atgaagaaat
    55021 gaaaaaatac tatgatacac ataaagatga atttaaaaaa gatgaggtag aagcttctca
    55081 tattttattg aaaacagtag atgataataa caagccactt tcagataagg aaaaagctga
    55141 agctaagaaa aaggctgaag aggctcttaa agaagttaaa tcaggtgagg attttgcaaa
    55201 agtagcaaaa aaatattcac aagatacttc agcaagtgat ggtggtaaat taggattctt
    55261 ttcaaggggg caaatggttg ctgaatttga agatgctgct ttttctatga aaaagggtga
    55321 agtatctgat ttagttgaaa ctcaatatgg ataccacata attaaagtga cagacagaat
    55381 aaatgagcaa acatcatttg aagatgctaa agaaactata aaagaccaac tgttgaaaaa
    55441 taaatatcaa gaacaaatag aaaaattaac taaagaagct aaggtagaaa aagatgaaaa
    55501 agtaataaat aaaatcacaa tctaagactt aaaaaaagag taatatgctt aaaaaagcta
    55561 tatctggata agatatagct ttttttgtat atttttctta acaatggtaa aaataaactt
    55621 aaagtaattt atggagggat taaaaaatat gaaagcaaca ggtatagtta gaagaataga
    55681 tgatcttgga agggtagtta tcccaaaaga gataagaaag acattaagaa ttagagaagg
    55741 agacccttta gagatattca cagcaaaaga tggagaagtc atacttaaaa aatactctcc
    55801 aataggtgaa ttaaatgaat tttcgcaaga atatgctgaa acattagctg aagtactagg
    55861 atatggagtg ttgataacag acttagattc tataatagct gtgtctaagc ttcctaaaaa
    55921 agattataaa gaaaaaagta taagtgatga gttagaagca ataataagtg aaagaacagt
    55981 aaaatattca aaagataaaa acattttacc attattcaag gaagaccaaa aagaatatac
    56041 tagtcaagtt atcatgccta taattagtgc atctggtgac tgtataggtt caattgtagt
    56101 tgtttcaaag gataaagata caattgcaga aagtgaagaa aaatctttaa aaattgctgc
    56161 taacttttta ggaaaacaag ttcaataatt ttatcataaa gaccttttac atgaaggtct
    56221 tttgaagttt ttgtgtaaaa tattgaatat agcattaaaa atatggtata ttaaagtttg
    56281 ttatataaac agtatggagg ttatgttatg aacaataaca aaaataaaga ctcctttcta
    56341 aaaggagccc ttatacttgg gctagcaggt gtaatcgtaa aaataatggg tggatttttt
    56401 aggattcccc ttggaaacat gattggttca gaaggaatgg gatactatca ggctgcttat
    56461 cctgtgtata ctctattttt aacattagct actgctggat ttccaacagc tgtggcaaaa
    56521 ttggtttcgg aaaaagttgc aattggaaat tttaaaggtg caaataagat atttaaggta
    56581 tcacatacag ttttattcat taccggtata atatcatttt gtatattatt ttttggagcc
    56641 gactacatag taacaaacgt aatgaaaaat ccaggtgcgt tatactctat gaaagccatt
    56701 gctccagcat tactatttgt tcctgcaatg tctgcatata gaggatattt tcaagggaga
    56761 caagatatga ctaagattgc tgtgtctcaa gttgcagagc aattttttag agttgtatta
    56821 ggtcttactt tggcctactt gcttatgaag agtctaggtc agacttttgg tgcagcaggt
    56881 gctatatcag gggctacaat aggttcaata gcatctatgc tttatttggt gtttgcttat
    56941 atgctaggga gaaaagagcg tagagcagag atagatgcaa gccaaagatt taaagatgaa
    57001 agagtgtctt atatttttaa aaagctttta actgttgcca ttcctataac aataggagca
    57061 tcagtaatgc cacttgtaaa tatgatagat aatgttattg taataagaag acttatggaa
    57121 gcaggattta catacaaagt ggcaaattca atgtttggtc aattaacagg tatggcaatg
    57181 gccacaataa atttaccagc agtcataaca actgcaatga gtatgagctt agttccagca
    57241 atttctaaag catatgcatt aggaaataag tcaaaagcta gaaaagatac taagagtgca
    57301 gttaaggtaa ctttacttat agtattgcct tgtgcgtttg gtatggcttc tttagcaata
    57361 ccaataatgg gtcttttatt tccacatgaa ccatcttctg taggaactat tttgtttact
    57421 cttactccat gtgtattatt tttaggatta atacagacat tgactggtat aattcaggga
    57481 atgggaaaac caatagtacc tgtaattgct ttatgtgttg gtatgctatg taaaattgta
    57541 ataagttata ctttaacagg tataccagat attaatgtac tgggttcagc atttggtaca
    57601 gttacagcat actttgtggc agccatgatt aacttactat atgttaaaaa acacatgaat
    57661 gtaaactttt ctaaaaaaga atttataata aagccattta taacagttat gacaatgttt
    57721 ataatggtta agttgagtta tggtgcttta gttggattct taggaaacag catatctaca
    57781 ataattgcaa tatgtgttgg tggaattgta tatgtagtag taatacttgg aataggtgga
    57841 attaaaaaag aagagattct aactatgcca aaaggtgata aattatataa attgttaaaa
    57901 aaagttaaac ttataagata atataggaat atatatgcaa ataaaggaaa tactatacaa
    57961 atagtaaatc tccttatttg tataataata taaaaataaa gtgaaatttg ctaataggag
    58021 tgatgttatg ggtaagataa gtattgtagg tcttggacca ggagactatt ctcttataag
    58081 ccaaggtgtg ttagaatctt taataaatag ccctaaagtt ttttttagaa cagagaaaca
    58141 tccaataatt gataaactta aagaaactat acaatacact tctttagact acttttatga
    58201 aaaagaggaa aattttgata atgtttattt gaaaatatct gaatttatca tagaagaatc
    58261 agcaaagggt gacctagtgt atgctgttcc tggtcatcca agagttgcag agaagactgt
    58321 aagtataata gagagattag ccaatgaaaa gcacatagca gtagaaatat tgccttctat
    58381 gagctttgta gacgctatgt ttaactattt ggctatagac ccatctgagg gatttaaact
    58441 ggtagatgct tttgaaatag aaaattcata tatagacttg gatacaagca tgataataac
    58501 tcaggtatat gataaattta tagcatctaa tgtaaagtta aaacttatgg aacattatga
    58561 ctataatcaa gaagtatgta tagtaaatgg agcaggtgtc aaagatttag aaagtaaaaa
    58621 gtttataaag ctttgtgaat tagacagaaa tgaaaacttt tttgactatt taactagctt
    58681 atatataccc aaaagttcta aaaagatgta taatacagta catgacttag aaataatagt
    58741 taatacactt agaagtccat ctggatgtga atgggataaa aaacaaacac atcaatcatt
    58801 aaaaaattct gttatagagg aagcatatga actttgtaat gcaattgata ataatgatat
    58861 agatgaaatg gtagaagagt taggtgatgt tcttttacag gttatattcc attgtcagat
    58921 aggaaatgag gagggctact ttgatttaaa agaagtagta aatggcatat gtaaaaaatt
    58981 aattcataga catcctcata tatttagtgg tgcaaaatta gatatgtcta agtttgagaa
    59041 aacttgggaa gaattaaaga aagaagagaa aggcgaaagt actataacag atggccttag
    59101 aaggatacca aaacatttac cagctcttat gaaggctagt aaagttcaac ataaagcagc
    59161 acttgtcggc tttgattggg acaatgtaga agatgtattt aaaaaaattg aagaagaata
    59221 tcaggaatta cttgacgaac acagggtcgg gaatataaaa tacataaagg aagagctagg
    59281 cgatttatta ttttcgatag taaatctagc tagattttta gacatagact caggagaagc
    59341 cttgaactgt actacagaaa aattcataaa tagatttgac tttatagaaa aaagtgcaat
    59401 gaacttgaat aaaaaattag aagacatgac acttgaagag atggatgagt tttggaatca
    59461 ggctaaaaaa caataaaatt gtggaaggaa atttgtcaaa aatctagaac ttttatcaca
    59521 aagatagaag tctatattat aaacattttt aggaggtaaa tatcgtgaat aaagctgaat
    59581 tagtatcaaa gatggcagaa aaaagtggat taacaaagaa ggaagcagaa gctgcgttaa
    59641 acgcatttat gagttctgtt caagatgcac tagtaaataa tgaaaaagtt caattagttg
    59701 gatttggaac atttgagaca agagaaagag ctgctagaca aggaagaaat ccaagagatc
    59761 cagagcaagt tatagatata ccagcttcta aagcaccagt tttcaaagct ggaaaaggat
    59821 taaaggatat aataaatgga taattagaaa tcttgtgaaa aagtgtggat aaatttgcca
    59881 cactttttct atagaaccaa ggaaggtgat aattatgaga ttagataaat ttttaaaagt
    59941 atctaggatt ataaaaagaa gaactgttgc taaagatgca tgtgataaag ggattgtcac
    60001 tataaatgga aaagttgcta aatcttcttc agaggtgaat attggagata cattagaaat
    60061 acaatttgga gagaagaaga tgaagtttaa gataaatgaa gtaaaagagc atgtattaaa
    60121 aaatgatgca aaagaaatgt acgaaatttt agaataaaat taatagtcct ctagtatatt
    60181 aatagtagta ttattgaaat atttactggg gggatattat ggaacagaac ataactttga
    60241 aagatagatc aaagctggtt atttcgggag tcgagcacat atactctttt aatgacaaaa
    60301 gagtagagct caaaacttct gtaggcgaga tggtaattga aggcgaaaac ctagatatga
    60361 gcaagctaag tatagacgaa aatataatta gcatagatgg aactataaat tctatggtat
    60421 atgcaaagcc taaaaagcca caagagagtt tcttgaaaaa ggtatttaga tagatgatac
    60481 cttttactca agatgtaagc attttttatg ctactattta tggtggaata ctcatagggg
    60541 tgttgtttga tttttataga gggctaagag ggaattttaa attcatcaat tattttgcta
    60601 taatctttga tgtattgttt tggtttctag ctacggttat aatattcgta acaataaacc
    60661 ttacagaatt ttttgattta agatattatc attttgtggc tttgtttatt ggttttattt
    60721 tatactataa caccataagt aaaattgttt tatcaattat caataaaata attcgttttg
    60781 tgagaaattc ttttaaaaaa gttacacatt acatagtcag ttttttaaat aatttgtatt
    60841 acgttataat ctattcacta cacctactat ttgatattat attttatata ccaaacatat
    60901 ttatagcaac aagaaaaagt ataaaaagaa aatcaaataa aaaattaaag aacaagaaaa
    60961 aatcaaaacc taagaagaaa aaaaataaaa ctaaaaaaag ggtgtaggaa aaatgaactt
    61021 aagaaaaaaa ttttcaggac agattattgt tatcagttta tttttaggaa tatcaatttt
    61081 tagtatgatg acaggatttg tatttgagta tacaaaagct aaggaatata aaaaagaaat
    61141 agcaagtcta aataaacaat taaaaaagac tgaaatacaa ataaacagct taaagaaaga
    61201 tgaaaaatca tatgaaggag acttagagga tatagcaaga aaaagattga atatggtaaa
    61261 accaaatgaa acagtttatg tagacataaa tcgttgatta aaacttgcta ataagtttac
    61321 agatgtattg attttaaaat ttaagattta ataaaaaagt cattcagtta aggatggctt
    61381 tttgttttta ttgaggaggg aatttcataa tgaaagtagg agctatagat attgggacaa
    61441 actcaatgag attactgata gcagattata gagatgggaa ttttataaac agaaaaaaat
    61501 ttgttaatac aactagaatc ggttatggtg tggatagtaa aggatatata aaagaagatg
    61561 ctatcaaaag aaatataaaa gcattaaaag aattttctga taagtgtaat gatgaaaagt
    61621 gtgaaaaaat ttattgtatg gggacatctg ctcttagaga cagtaaaaat ggagattact
    61681 ttgttaaatt agctaaagaa gaaactggaa tagatgttga tatagttacg ggaatagaag
    61741 aatcaaattt gggctttaag ggtgttttag aaggaataca aggtgatgat actattattg
    61801 ttatagatat tggaggaggt tcaacagaat ttattgtagg tgattcagaa ggaattaaat
    61861 ttaataaaag tgagaatgta ggtgctctta ggatgacaga gaggtttttg aagcacgata
    61921 ttattgaaga tgaagagttt gaagctatga gttcatttat atatgatgag attgacaaaa
    61981 cgttaaatca tataaaagac agaggattaa aaactcttat aggtatagga ggtacgatta
    62041 catcattatc agcaatgaat caagaattag agatttactc tatggaaaaa atacataata
    62101 gtaaaataca caaaaaagaa atagaagaaa ttctacaaaa attaataaag atgacattaa
    62161 gtgataaaaa gaacttaaaa gggctacaag aaaaacgtgc ggatattata actgctggtg
    62221 taaaaatatt gaatataata atggaaaaat tagaaataga agaaataacc gtaagtgaat
    62281 acgataattt ggaaggctta atatgtcaaa agtcaaaaaa aatgtattaa tattttttga
    62341 tttttaaaac cgattatgac aaaaaaaatt actcctcttt gttacaattc ttaatataaa
    62401 caaaagagga ggttttttta tgcaaagaag tgtagcagtt gtgaagaata agactgtaaa
    62461 accaaatgtc ataaaattaa taagcggata tattgatttt actacggcgg cattcgctgt
    62521 gatgggattt ttacttagta ggtctattat agtagactct gtagctcctt taggaattgc
    62581 cttttttata tgtgcatcaa agattgataa gtacaagata cctgtattca tatcaacatt
    62641 attaggaata ttgttatcat ctaatgattt tggaaatgta gcaaaatatg ctgtgtgcct
    62701 tacaatattt atggctatga ataaaaaatt aaaattatca gattcaattg ctaaggttgc
    62761 atttataggt gcaataatac tacttccaat ctccatggga caagctttct tttcaaatag
    62821 gtatgtatat ggtcttctta tagcaggagt agaagcaata ataatgttta tatctatata
    62881 tgtgttttct tatgggatag gtttaatggc caatgtcaac aataggatgt ctgtacggac
    62941 agaagaagct atatcaataa gtttactgct aacctttagc ataatgggaa taggagatat
    63001 atctctgttt ggaatatcaa taaggaccat tttatcgacc gtattgatat tgctgacctc
    63061 aatagtaggt ggagctacca tgggagcatc tagtggtgta attattggtg tagcatccat
    63121 tttaaataat atgacatcag ctgtttatat ggggatatat tctttttcag gattaataag
    63181 tggagcattt aataaaataa ataaatattt ctgtatacta ggatatattc taagttggac
    63241 aataatatac ctatatactt ctggtattac ttctaatatg atgcaattaa gagatatact
    63301 attaggttgt ttgatagtac tagtattgcc agagagatta tttaataaga ttgaaaaatt
    63361 aataaaaagt aatgtggctt caaatgaaat cgtatacgat tatattatga gaagcaaaaa
    63421 cctaactaat agcagattga acagtattta taaaacttat gatgaccttg cagatacatt
    63481 tgataagata agagaaaaag acaaagtgct agaccaaaga gatatagcta atgtaataga
    63541 tatgattcat aatgatgaat gtaaaagttg tagtatgaga agaatgtgct gggagtcaag
    63601 atttaatcat acatacacta tgatatataa cattcttgaa aaaattgagg agaaagggga
    63661 gttaagtcta aacgatatac ctaaaaattt tagaaaggaa tgtatgaaac cagagtcgat
    63721 agtgaaaata tcaaatcact attacaaaat gtttgtatta gattatgatt ggagtgtgaa
    63781 gttttcagaa agtagaaagt taatagcaaa tcagataaga agtatttcaa aatccattaa
    63841 atccttatct caagatttag aaggtgacat aatgctagat atagaaaagg aaaaaaatat
    63901 atatgaacag ttagaaagat atgatataac agttgataaa gtaagttact taacaaaaag
    63961 taacaatgag tttgaaatat caatagaaaa gaaaacttgt catgatggat gtatgtgtga
    64021 agataaaatt gtaaatataa tttcagacct agtaggtgaa aatatgtctg ttagaaaaat
    64081 aggatgtcac tgtttaggag gtaaatgcaa ggcaacattc gttaaatctc aaaaatataa
    64141 ggctgttaca gaagtttcag caatgtcaag ggatgggcat atcctttgtg gagacaatta
    64201 cacatacatg gagataaatg atggtaaata catgatggct ataagtgatg gtatgggaaa
    64261 gggtaaaaaa gcatatgaag aatcttctgc cactattgat atactggaaa aaatgataga
    64321 tgcaaaaatt aaagatgaga tagtcattga tactataaat aatatgttgt tgttaaaatc
    64381 ttcagaagag atgttttcaa ctctggattt gggaatttta gatttaaaac gaggttgttt
    64441 agaaactata aagatgggag cgtgttctac ttatataaaa agagaggatg gagaagttga
    64501 cttaatatca tcatcatcat tacctgtggg tatattatca gatgtaaaaa ttgatagaaa
    64561 aaatgtaaaa gttaaggaag gagactatgt tataatggtt tctgatggaa ttgtagatgc
    64621 aggaagaaat aacaatttag gagacaattg gttaatatac ttcttaaaga atatagagac
    64681 tacaaatcca aaggaaattt caaatttaat attggataga gcattagagt tacaagcgtt
    64741 acaaatcgaa gatgacatga ctgttttagt tacgaaaata tgtacaaaat aaggtttaca
    64801 agattatgtg tataagatgt ggataacttg tgtataatat gttaatagac ttttgaaaaa
    64861 agtatagtta ttaacaaaaa taacatataa atcaacaaaa tttgttgata agtatggcag
    64921 aaatgttaat aaaatgtaaa aaaagaaaaa acaaaagcta ttatcaaaag agattcatgt
    64981 tgaaataact aaatttctaa gtaaagaaaa cctgtgaata tgttgattat tatgtggata
    65041 actattaatt cgatatttat ttatatagta tgaataattg aataatatat ctaaaaaaag
    65101 ccatcctatt attaagtaaa tttattgaaa ggatggcttt ttatgaatag aaaattgtgc
    65161 aaagcaataa tacctttatt tatttctatt ttttgcatgt taataataag tataaaagct
    65221 gaccaaggat atcaaaagaa taatgacaga gcaattgctg tcatgaataa taatgatact
    65281 gaagatgatg ctgaaaaaaa acaagaagta gactatgaaa aaacatgttg gaatttgcaa
    65341 tctttgttca aaagtgatga ccaatggaaa aaagaactta agagttttga taaagatact
    65401 aaagagttga aaaattacat aggtaaagta acaaaatcgc caacacattt gtcttttgcc
    65461 ttaaacatta aggaaaaact tgatataaga ctaaataaac tttctgccta tgtaaaatta
    65521 aaacaagata ctaataaaaa ttcatataag tacttagata tgagtgatag tatgagtaaa
    65581 tcatatggga attatatggg gatttgttca gatttagaat tagaaatact aaaattatca
    65641 aacaaagatt acaagaaaat tatttcaaat aaaaatataa ataggaaata tggtgcatat
    65701 ttaagagata taagaaggaa taaagtacat tatttggatg ataaatcaga agatattcta
    65761 agcaaagtat cttcaataag tagtcttcca agccaagtat atgaattatt tagaaatatg
    65821 gatagaaaaa ctaatttgac accagcgcaa tatgcaagtg aattagagtc agtagataga
    65881 gaaaatagaa aaaaagctta tcaagatgaa cttataactt acaatgataa tataaataca
    65941 attgcaggtt taattactgg tcaagttaaa aagaatattt tttattctca ggaaagaggt
    66001 tatgagtctt ctttagaaat gtacttggaa tctgataatg tagatgaaaa agtatacaat
    66061 aatttgataa ggactgtaaa tagtaatatg gacagtctac acaaatatat agatttaaga
    66121 aaaaaagtat taaaattaga taaggttcat tcatatgata tgtttgtgcc tatggttaag
    66181 gctgttgata ataatattaa ttatgaaaag gcacaaagta tagtatattc agcgttgtca
    66241 cctttaggaa aagaatacaa tgatgtagta tataaagctt tcaatgaaaa atggatagat
    66301 gtttattcac atgaaaataa agtaagtggt ggatactgct tatctgttta tgaaaatcat
    66361 ccatatatac ttttaaatta taataattca ttaggttcag tttcgacttt atcacatgag
    66421 cttggacatg ctgtatatga atacttaagt tctaagaatc agaattattt taattcaaat
    66481 ccgtctatat ttactcacga agttgcatct acaacgaatg aagcattact ttacgagatg
    66541 cttataaaag aagctaaagg caatgatgaa aaagcttatt atataacaca gtatttagac
    66601 ttgataaaag atactcttta tacacaaact atgtatgctg aatttgaaaa aactatacac
    66661 gagttagtag aaaaaggaaa aagtgtaaac gcattagtat taaatgatgt ttggggacaa
    66721 cttcttaaaa aatattatgg acaaagctat gaattagacc aattatctaa ggtcggatgg
    66781 gctagaatcc cacattttta taatagtttc tatgtctata aatatgctac aggttgtagt
    66841 gcaggagtaa gttttgccca agacatccta aagaatggtt cagataacta tatgagcttt
    66901 cttaaaaagg gaagttcaga ttatccaata aacttgttaa aatcaagtgg cataaattta
    66961 actaatacaa aacccataga aaatacaatc aaaaaatttg atagtttagt agcagaactt
    67021 gaaaagctat tataaacatt attgtaatcc acatggtaaa tatatcgaat taatgataaa
    67081 atatactaaa agtttaaagt cctatcaaga taggactttt tatttattaa ttagtgggag
    67141 atgattctat gcaagttaaa gttaaaaagg ctgtaatacc agcagcaggt ttaggaacta
    67201 gatttttgcc agctacaaag gcacaaccaa aagagatgtt accaatagtt gataagccaa
    67261 ctctacaata cataatagaa gaagctgtgg cctcaggaat agaggaaata ctaataataa
    67321 caggtagaaa taaaaaatct attgaagacc actttgataa atctgtagaa ttggaacttg
    67381 atttagagaa aaaaggtaag aaagaattgt tggaggtagt acaaaacata tctaacatga
    67441 ttaacataca ttatataaga caaaaagagc caaaaggatt gggagatgca atttattgtg
    67501 cgaggcattt tataggtgat gagccgtttg cagtaatgtt aggggatgat attgtagata
    67561 atgatgtacc ttgtctaaaa caactaacag atgcatatga ggaatataga actacaatat
    67621 tgggtgttca aaaggtaaat caagaagata ctaataaata tgggataata gaagcaaaaa
    67681 atatagaagg tagagtttac aaggtaaaag acatggtaga aaagccagag tcaggaaaag
    67741 ctccttcaaa tattgctatt ttaggtagat atataataac tcctgaaatc tttgatattc
    67801 ttaaggattt accaccaggt aaaggtggag aggtacaact tacagatgct ttaaaaatat
    67861 tatctaagaa agaagctatg tatgcataca attttgaagg caagagatat gatgttgggg
    67921 acaagctagg atttttagaa gctactgttg actttgctct aaagaaagaa gaccttaagg
    67981 aagattttat aaaatatttg aaacatgtat gtagtgaatt tgataaaaat aacaatgtgt
    68041 tatacaataa tacagatgaa aaaatagatt taattgaagt caatgaagct agagaacttg
    68101 aaattcaaaa ataattaatg aaaggtgatg tatggtggca aaatcaagtc agaaaagaat
    68161 taatagaata atagctgttg ggattgtggg aatcctcgta ataacgagta taacagctgt
    68221 tttgagtatg attgcaacta tgtaataaga taaatgacag cagttgatat acataaatat
    68281 aaaaaccata tataacttga tgtagtcaaa aacttacaat attttagtta tatatggttt
    68341 ttagaattta taaatgtaaa aaaaaatttt tataatagtt gcatatttta aaggaaaata
    68401 ttattataag atataaatat agtgataaat ttataaaaac gtgctaagat tggacttgaa
    68461 atacagtaat atagtaggta ataatgtttt aaattttatt tattgaccat aatatataaa
    68521 taatgatatt attagactta actgtttaaa taaaactttt ctttttcatg ccttcaattt
    68581 ccaaaataag tatgtatata aatgaatata tagatgagga ggattttttt gattttagat
    68641 gataaagtat tagaaggatt aggtagtaag accttagttg agctacgaga gatagctaaa
    68701 gaattaaaaa taaaatcaat tactacatat aagaaaaatg agttaattga gattataaat
    68761 tccaaaagta aaaatgagga aaaagtaaac gaagagacta aagaaaaaaa tgaagatatt
    68821 aaagaagaca taaagaatag aaaagaaaat atagagcgtg aaagtataga aaaagaagtt
    68881 gaatataaga gccctaccaa atcatacaac aagaaagaaa tagataccca aaatatttcc
    68941 caaaaccaag aaaatagaaa tcaaagaaat gactataata agacaacgag tgtaaatgat
    69001 agtaataagt catcaaatat atctaataga atggtcagaa ataataataa aaactattat
    69061 atgcctaaac aagttgatga atctaagata gtagatgaat ttaacacatc aaaagaggat
    69121 gaagtagtag gtgtacttga aattctgcca gatggatttg gttttttaag aggttcaaat
    69181 tatttgtcta ctgaaggaga tgtttatgtt tcaccatctc aaataagaag atttaatatg
    69241 aaaacaggag acaagattaa gggaataact agacatccaa aaagtggaga gaaatttaga
    69301 gcacttttat atgttcaaaa aataaatgat gaaaaccctg acacagctat acaaagaaat
    69361 gcgtttgaga cattaacacc aatatttcca gaagaacgac ttacactgga aactaataga
    69421 aatgaaatag ctacaagaat tatagattta atttcaccta taggaaaggg acaaagagga
    69481 ttgatagtag cacctccaaa ggctgggaaa acagttcttt taaaaagcgt tgcaaatagc
    69541 atagctaaaa atcatccaaa tgttgaactt atagtactcc ttatagatga aagaccagag
    69601 gaagttactg atatgaaaga atctattgaa ggagacgtta tatattcaac ttttgaccaa
    69661 gtatcaagtc atcatgtcaa ggttgcagag atggtgttaa atagagctca aagattagtt
    69721 gaacatggta aagatgtagt aattttacta gatagtataa ctagattggc aagggcatat
    69781 aaccttacaa tatctcctac aggtagaact ttatctggag gtattgaccc tggtgcactt
    69841 catggaccta aaaagttctt tggtgcagca aggaatatta gacagggtgg ttctttgaca
    69901 atattaggaa cagcattggt tgaaactggt tctaggatgg atgatgtaat atttgaggaa
    69961 tttaaaggta caggaaatat ggagctacat ttagatagaa aattagcaga aaaaagaata
    70021 ttccctgcaa tagatattta caagtctggt acaagaagag atgatttatt gcttgatgat
    70081 gaagaaaaga ctgctctttg gagattaaga agagaaatga gtaataattc agtaatggaa
    70141 attacagata aagtcattga acttataaag agaactaagg acaataaaga gtttgtaaaa
    70201 tcaataaaga atttgtaaaa tcaataatac aaatgcaaat atggattata taaactaata
    70261 gaaaaatcac ttgaatggca taataagttg tgctataata atgtagttga taatgtaaaa
    70321 agaaagttaa tataattaat ttttttaaat aaagagaaga ggtgactata atgcaaaagg
    70381 aaatacaacc aaaatacaat ccagttgaag tgcgttgtgc ttgtgggaac acatttgttg
    70441 ctggttcaac taaggacgaa ataaaagttg aaatatgttc agagtgccat ccattctata
    70501 caggaaaaca aaagaacata gaaaaaggtg gaagaatcga caaattcaag aaaagattca
    70561 aaatggacta atttttataa aagtggagtt ggaggaagcc aactcctatt ttattacaaa
    70621 aaaacattca tattctactt taaattgtct ttttgtatta taataataaa tatgtaaaat
    70681 tgagtattct aaatacaata aaatgaggtg agtggatggc aaaacaagct gtaggtgggc
    70741 aagctgttat tgaaggtgta atgatgcagt caaaagacaa aagagcggta gctgttagaa
    70801 aaagtgacgg agaaatagca ctaaaagaag atagaataaa aagttgggta agagataaga
    70861 atatagataa gatacctttt gttagaggtt cttttgttat gatagataca atgattcaag
    70921 ggataaaaag tttaaacttt tcttcagagt tttttatgga agaagctgaa gaggataaat
    70981 ttgatttatt tataaagaaa atttttaaag ataaggcaaa tgatataatt ataatatttt
    71041 cattggtcat agcaatgtta ctttctgctg gattattcat ttttatacct acattggtag
    71101 gaggagcttt ttctaaagta atgcctaatg attttatgct taatttaata gaaggaatca
    71161 taaggatagc tatattattt gcatatatag tattgatttc acgaagtaag gatatagaaa
    71221 gagtctttca atatcatgga gcagaacata aatctatata ttgctatgaa aatgatttag
    71281 aacttacagt agagaatgct agaaaattta aaagattaca tcctagatgt ggtacaaatt
    71341 tcctatttat agttatggct gtatcaataa tattgtttgc attttttggt tggccaaatc
    71401 caattcttag aatatttatg agaattatat gtgtgcctat agtagcaggt ttatcttatg
    71461 aggtaattag agttcttggg aaatatgata atggatttac taaaattatt gcatatccag
    71521 gaatgatgtt gcaatatttt acaacaaaag agcctgatga tgagcaatta gaggttgctt
    71581 tggaagcatt gaaagcagta gtagattaga gaaaaggata tttgttatga cgataaaaga
    71641 tataattatt aaatattcag ataaactaaa agatataagt gatactccaa gattagatac
    71701 agagttattg ttacaaaaaa cattgggtgt tgatagatta tatattcact taaatctgaa
    71761 taaagagcta actgaagaac aaaaaacaaa atttatgggt tttgcagaag aaagattaaa
    71821 tggaagacca atagcatata tagttgaaaa tagggagttt atgggattag atttttttgt
    71881 taaggaaggc gtattgattc caagaccaga tacagaaact ttagtagaag aaataattga
    71941 aatatgtaga gaaaaaaaag atgtaagtat attagatata ggaactggtt ctggagctat
    72001 tacaataagt ttagcaaagt acattgaaaa ttctaaaatc atgtcttttg atatatcaga
    72061 gacagcatta gaaatagcta aaaaaaatgc tattataaat gaagttggtg aaaaaataaa
    72121 gtatattaat tctgatttat ttacagcaat aagtgatagt aacataaaat tcgatatcat
    72181 agtttcaaat ccaccatata ttaaaaaaca agatatagaa actctgcaca aacaagttaa
    72241 agattatgaa ccatataatg ctcttgaagg tggagaagat ggattagact tttatagaag
    72301 aataacagaa caaggtaaga aatatttaaa taagtgtgga atattagcat atgaagttgg
    72361 tcataatcaa gctgaagatg taataaatat tatgaaaagt aatggatata aaaaaatata
    72421 cacaaagaag gatattcaag gcattgatag agttgttata ggttacaata tatgatataa
    72481 tcaacaattg atatgttaca tttaatcgag gtgaaagtat gttaaaaaaa ttagaggtat
    72541 tggaagatac atataaagac ttaagtgaaa aaataggtga tccggatgta ataaatgatc
    72601 aaaaagtttg gcagaaatat ataaaagaac atgctgactt ggaacctatt gttatgaaat
    72661 acagagagta taaaagcgtt ttagatagta taaaagaatc aaaagaaatt ttacaagaag
    72721 agtcagatga agaattaaga gaattagcta aaatggagtt agctgagatg gaagaaaaag
    72781 tagcacctct ggaggaagaa ataaaaatac tattattgcc taaagaccct aatgatgata
    72841 agaacgttat agttgaaatt agaggtggag ctggaggaga tgaagcagct ctatttgcgg
    72901 gtgatttatt tagaatgtac tcaaggtatg ctgaaagaag aagatggaaa atagaattat
    72961 tgagtgcaag tgatactgga gttggtggat ataaagaagt atcttttatg ataaaaggta
    73021 aaggtgctta ttcaagatta aagtatgaat ctggagttca tagagttcaa agaataccat
    73081 caactgaatc tggtggaaga atacacacat caacttctac tgttgcagta ttaccagaag
    73141 ttgaagatgt agaggttgaa ataaatccaa atgatttaag aatagatgtt ttccgttctt
    73201 cgggtaatgg aggacaaagt gtcaatacta ctgactctgc tgttagggta acacatatac
    73261 ctacaggtga agtagtatct tgtcaagatg gaaaatcaca attaaaaaat aaagagcaag
    73321 ctttaaaaat attaaaagct agactttacg ataaagcatt ggcagaacaa cacaaagata
    73381 tagcagcaga aagaaaaagc caagtcggaa caggagacag gtcagaaaga ataagaacat
    73441 ataatttccc tcaaggtaga ataagtgacc atagaataaa tttaacttta tataagttag
    73501 atgcattttt agatggagat atagatgaaa tgatagatgc tttaattact gttgaccaaa
    73561 cagaaaaaat gactgcaata taagtaatgt tttaaagaag ctgtttcttc ctagaaatta
    73621 ttttctattt tgaaacagct attttgcatt ttaggtcatg ttatcatatt ctattgtata
    73681 taattgttat atacaagtat aggagggtta tatgatacta aaagtaacaa taattgggct
    73741 tttggcaggt gttataggga caggattagg aggagtaata tcagccattt ttaaaagaga
    73801 ggtcgataaa tatctaagtt tttttatggg attatctggt ggaataatgt tggctgtagt
    73861 ggtgtttgat ttaatgaaag aatccatgga caaaatgggg ataatcaata cagttatatt
    73921 tacgtttgtt ggagctctca taactatgta cataaaaaca aaattagatg tgtctggaaa
    73981 tatggcatct ggatatctta tattcataag tatattacta cataatttac cagaaggact
    74041 agccattggt tcttctttta tgtcaactga aagtttaggt attacacttg ctatagttat
    74101 aggtctacat aatataccag aagggttagc tatggcatta ggcttagttt gcaataaaat
    74161 gaaactaagt aaagttattt tgtttactgt aatagctgga ttacctatgg gtctaggaag
    74221 ttttttaggt gtttattttg gaggagtatt tacttctctt ataggagtat ttcttgctac
    74281 agcaggaggt actatgatgt atgttgtatt ggaagaaatt tttccacatt caaaaagtgt
    74341 gtattgtata attggtttct tgttaggtac aatgattgta aattatatat aaaattaaaa
    74401 tgaaagcagg catacaaaag atgaaaacta ttataagtaa tattgatata aataatattg
    74461 attatgagga aataaaaata caagcaaaac ttcttagaga aggtaaaaca gttatttttc
    74521 caactgagac agtatatggg ttgggtgcaa atgcattaga tgaaaatgca gtaaagaaga
    74581 tttatgaagc taaaggaaga cctagtgaca atccattgat agtccatata tatgaaaaag
    74641 aagaagtata tgacttagcc aaagatataa gtgataaagc taaacttgtt atagaaaagc
    74701 tttggccagg acctataaca attatattaa ataaaaaaga tataattcca tacaaaacta
    74761 gtggagggct tgatacagtt gcaataagga tgccttctaa tgttattgcc agggcaataa
    74821 taaaagaagc tggtatacct attgcagctc cttctgcaaa tatctcaggt cgcccatctc
    74881 caacaaaagc aaaacatgta tatgaagaga tgaatggaag agtggatgga atagttttag
    74941 gaggagacag taattttgga ttggagtcaa ctgtattgga tttaacagaa gagactccta
    75001 tgatactgag accaggaagt ataactaaag aagttttaga ggaacttctt ggagaagtaa
    75061 agcttgaccc atcattaagt aaaaaagaag ataatcaaaa agctaaagct cctggaatga
    75121 aatataaaca ttattctcca aatgcagatg tatatataat atctggaaaa agagaaaatg
    75181 tagcaacaaa gattaatgat atgataaaat ctaatagaga caaaggtcta aagacaggtg
    75241 taatgtgtat cagtagaaac cgagagtttt atgatggaga agtaatcgat ttaggaaact
    75301 ctcttgaaga agttgcaagt aatctgtttg atgctcttat agaaatggac aaaaagggcg
    75361 ttgatgtcat atattcagaa gagttcccta agactggagt tggacaagca attatgaata
    75421 gactactgaa gtcagcagga tacaaagtga taaaggctta agagggagtt gtaaaatatg
    75481 aatatactta ttgtgtgtac aggtaatact tgtagaagcc ctatggctga ggctatacta
    75541 aggaaagcaa ttaaagaatc tggaagaagt attgaagaat attcgatatc atcagcaggt
    75601 atatctacag caaatggaat gggtgcttct gaaaattcta tagaagtact aaaagaaatc
    75661 ggtatagact tatcaaatca tagaagtaaa gtaattacta aaaaattaat tgatgaatca
    75721 gatataatac taacaatgac taaatctcat aaagaaattt tagtacaagc agttccaaaa
    75781 tgcaaagaaa aagtgtatac ttttaaaggg tttgcaaata aaaatgagga agatatatct
    75841 gacccatttg gtggaaattt ggatatttat agaagcacta tgagagaaat aatgtattct
    75901 gtcaacgaaa tagtaaaaaa aatatgaaac ggaggataaa caaatgaaga taggattagg
    75961 ctgtgaccat ggaggatata atttaaaaaa agaaataata agctatttag aaagtaaagg
    76021 tatagaatgt gtagattatg gaactaataa tgctacagat tctgttgatt atcctgttta
    76081 tggagaaata gttgcaaatt cagttataaa taaagaagta gattatggaa tattatgttg
    76141 tggtacaggg ataggaatat ctttagctgc taataaggtt cctgggataa gatgtgcagt
    76201 tgtatcagat gtattttctg caaaaatgtc aaaagcacat aatgatgcaa atatgttatc
    76261 attaggcgaa agagttttag gaaaaggtct agcacttgag atagttgaag catggattaa
    76321 tacggatttt gaaggtgata gacatgctag aagagtaaac atgattaaat caatagaaga
    76381 aaaacataat aaataataaa aattacagtt ttatcaggag gaattatcaa aatgagcaaa
    76441 gtggtagaga caaaccatcc attaatacaa cataaattaa ctttaatgag agataaaaat
    76501 actggttcta aagactttag agagctttta actgaaattg caatgttaat ggggtatgaa
    76561 ataacaaaag atataccatt aaaagatgta gaaatagaaa ctcctattca aaaaacatca
    76621 tctaaagtag ttgcaggtaa aaaattagca ataattccaa ttttaagagc aggtcttgga
    76681 atggtagatg gattagtaag cttaatgcca gcagcaaaag ttggacatgt aggactatat
    76741 agagacccag aaacattaaa accagttgaa tattattgca agcttcctca agacatagga
    76801 gaaagagata taatagtagt tgaccctatg cttgcaacag ggggttctgc tgtagcagct
    76861 atagatttac ttaagtctaa aggagctaaa agtataaaat tagctaattt agtagctgca
    76921 ccagaaggta tagcagaagt gcaaaaatat catgatgatg ttgatatata tgttgcatca
    76981 gttgacgaaa gattaaatga acatggatat ataattcctg gtcttggtga tgctggagat
    77041 agattgtttg gaactaaata aaaataaata actataaata tttattaggg actttcttat
    77101 atagtgtata taattttatg taagaaggtt cttttttata tattttttct caaaatagga
    77161 attatgaatt gataaatttc tcgaattgag aataaaaagt ttttaccaat taaaaaagat
    77221 tgcttatttt acaaggtttt atagaatagt agtctatttt aatgtggcat gttagttgct
    77281 tacgattaag attataggta ttaagtgtat tagttaaatt gagaattgaa tattaataat
    77341 attattggga gtggtaatac atgaagaatt gtatagcagt aagaggggct ggagatttag
    77401 caacagcagt tattcataaa ttacacaaca gtggttttaa agtagttgcg ttagaaatag
    77461 aagagccatt agctataaga aggcaaattt ctttttgtga ggctgtttat gaaaaaaaag
    77521 taactgttga aggtgtagaa tgtatatttt gcaatactga aaaagaaata gaagaagttt
    77581 tatctcaaca taaagtagcc ttgattatag acccaaaagg agaaaaatta tctaagttaa
    77641 atccaatcgt tttggttgat ggaatactcg ctaagaaaaa cttaggtaca actaaagata
    77701 tggcaccact tacaatagct ttaggtcctg gattttgtgc aggagaagat gtagatgttg
    77761 ttatagagac aatgagaggt cataatctag gaagaataat aactaatggt agagcagaaa
    77821 aaaatacagg agtaccagga gcaataaaag gtttttctaa agagagagtt atgcattcac
    77881 agtatgatgg tataatggaa aatgtatgta agataggtga tatagttgaa aagggagacc
    77941 tactttgtta tattaataat tatgaaaaaa aacatgaagt tagagcaaca atatctggag
    78001 tccttagagg tttattaaag gatggagcaa aggtgaacaa aaatttaaaa atactagaca
    78061 tagaccctag aaaagaagaa gttaagaatg cttttacaat atcagataaa gctagatgta
    78121 tagctggagg ggttttagaa gccatactaa acaatgggat ttatccccaa aattaattta
    78181 tattagataa agctattaat attttattaa gatgatataa taaatttaat agattaaaga
    78241 gagcatatga cgggtattta aaatttaaat ggtaaaaatg ctcttttttt attggacatt
    78301 caattaacat gtgtatataa tataaaaata agtatttatt taggttgaaa tctaataaat
    78361 atataatacc agtacataag caaagaggag aaaagtaaat tatgagacca tcatgggatg
    78421 aatacttcat ggaaattgca gaagtagtga aaaagcgttc aacttgtatt agaagacaag
    78481 taggagctgt aattgtaaga gacaaacaaa tattaacaac tggatataat ggttctccga
    78541 gaaatcttga acactgtgaa aatattggat gtaagaggca ggaattaaat attccctcag
    78601 gagaaaggca tgaattatgc agagcattac atgctgaaca aaatgcgata atacaagctg
    78661 ctcataatgg tattagtgta gatggggcaa ctttgtatgt tactacaaga ccttgtgttt
    78721 tgtgtgcaaa aatgtgcata aatgcaggta tattgaaaat tgtttatgaa ggtgattatc
    78781 cagatgatat gtctacagaa ttattaaaag aagcaggaat agaactcata aaattttagt
    78841 ggataaaatt tatatgacaa taaatgtcaa attatgacac tgaaatacaa tggtatcaaa
    78901 tgattaaaag aaagtatttg aaaaatcatc agattagtag taagatatat tttataatta
    78961 aataaattta tgagatagat taattacatg ttatttattt tataataatg agggatacta
    79021 tttatgagta aaagaaatac acatacagaa attgcaaagt tgtttagttt aataagtcaa
    79081 ataggattga tgattgtaat atcaatatta ggatgtactt tcttaggaaa atttttagat
    79141 agtaaattga atactactcc agttctgaca ataatatttt tattgttggg tgttggaggt
    79201 gcttttagtg gtgtttataa aactctaata gtatatacac gaaggaagtg atatattgga
    79261 tataaaatta cttaaccagg taaggtcagt aacaaaaggt atagtaatat ttgatgtagt
    79321 tttaattgtg ctaatgttga taacatcaac attaagtaaa ccagtattat taggacttat
    79381 atttggctct ataatagcta tgttaaattt tagattattg gcgatatcac tggaaaaatc
    79441 agtgacattt cctgctggga aggcacaagc ttatgcatca gcacaatatg ctattagatt
    79501 atttataatg gcagttgttc taattgcatc agctacagta ccacatttaa atataatcgg
    79561 aacagcattg ggattattga gcacaaagtt tgtcatatta tcaaaaaact ttataaataa
    79621 attaaagagg aaggaggcat aagtatgaat caagcgcatt attatctcat aggaaacttt
    79681 aagattagtg aaacaatact agtaagttgg ggaataatgg cctttttagc gatagcatct
    79741 tattttttga ctagaaactt aaaaaaagtt ccaactagta aagttcaaat attcttagaa
    79801 tttgcagtag gtggtcttgc taaaatggtt acagatgtta tgggtaaaaa tacagtaaaa
    79861 agaatgccat atatgatacc atacatagga agcttgtttt tatttttcgc atgttcaaat
    79921 ttaagcccat tacttggatt aaggtcacca acaaccgact tagacacaac tgctgcatgg
    79981 gcaatgatta cattttttat gatttatttt gcaggagtta aatttaaggg gttatcatac
    80041 tttaaagaat tggctcaacc acttgccata atgttaccaa tcaatattat aggtgagtta
    80101 gctagaccaa tatcattaag tttccgtcca tttgggaata ttttaggtgg aacaataata
    80161 atgggtctgt tttatcaact tttaggtttt atatctagtt taataccagg attatcaata
    80221 ccaattggag aaatattaat accagtccca ttacacttgt actttgactt atttgcagga
    80281 ttgttacaag catatatatt tataatgtta acaatggtat ttatatcaag tgcaggagag
    80341 ttagattaag aaatcaactt atattaagat aaaaataaaa taatttaaaa aattaaagtt
    80401 ttaaggagga aataattatg gaaacagcaa tagtagcggc agcatcagca ataggagcag
    80461 ggatagcagt tgcaacaggt ataggtgcag gtataggtca aggtatagca gcagctaaag
    80521 ctgcagaagc agtaggaaac caaccagaag ctaaaggtga tataacatca actttattac
    80581 taggagttgc tatagcagag tcttcagcaa tatatggttt ggttatatca ataatacttc
    80641 tattcgtaaa tccattcttt aaatacttag gaatgtagat ttagtcctta aatattttga
    80701 gataggttta taggtaaatc atctcaaact tataatcatg agatgaactt tatcatctcg
    80761 tgattataag tagttatgat ttatggaaag gaggataatt atggaaaaag cactagtagg
    80821 tataacgtgg gaatttgtgt tccaaattgt taatactttt ataatatttt tacttctgag
    80881 aaagctttta ttcaagccag tattaaatat aattgaatca agagaaaatg atattaaaag
    80941 tgatttggca gaaggcgaaa aagcaaaaaa tgaaggttta gctctgaaaa aagaatatga
    81001 gtcaaaaatc aattttgcca aggatgaagg tcaagaaatc ataaaacaag caactataag
    81061 agcagagcag aaatcagatg atatagtaaa tactgcaaag aaagatgctc ttgatataaa
    81121 agaaaaagca aacaaagata tagaacaaga aagacaaaag gttataaatg aaatcaaaaa
    81181 tgatatatct aacatagcac tacttgcagc atctaaagtt attgaaaaag atttagataa
    81241 atctaaacat gaagaattga tagaaaactt tataaaagag gtaggggaag ctaaatgata
    81301 aatgtaatag caaatagata tgccgaagcc ctatttcaat taggagaaga agaaaattca
    81361 actgatgtct tattcaaaga actagaaaaa gtagtagata tgatgactaa agttagtaaa
    81421 gatttctaca aagttttaaa atcaccatta gtttcaaaat cagaaaagaa aaacttggta
    81481 gaaattattt ttagtaagga agtaagttct aacataaaaa actttttaaa agttttagta
    81541 gataaagata gaatatcata tttagaagat atcgaattag cttataaaga attattaaat
    81601 aagaaaaaca atgtaattga tggagtagca ataagtgcta ttccaatgag tgaaacagat
    81661 attaaagaac ttgaagtcaa actttcaaat aaatacaaca aaaatgttac tatagaaaat
    81721 gttgttgaca agactatact agggggagtt ctagttagaa ttggaaatga acaaatagat
    81781 ggcactgtga aaactcgtct tgataagatg aaagaaaagc tatctgaagt aatatcttaa
    81841 gaatggcggt gaacccatga acttaaaacc tgaagaaata agttctataa ttaaacagca
    81901 aataaaaaat tatgagaata aagttgagtt gacagataca ggtagtgttt taacagttgg
    81961 ggatggtata gcgagtgtat atggattaga aaaagctatg tctggtgagt tgctagagtt
    82021 cccaggtgaa atatatggta tggcacttaa cttggaagaa gaagtagttg gagctgttat
    82081 ccttggagat gacagtgaaa taaaagaagg cgatatagtt aagagaactg gaagaatagt
    82141 tgaagttcca gttggagaag ctttaatagg tagagttgta aactcactag gtcagccaat
    82201 agatggaaaa ggacctatag cgtacacaaa aactagacca gttgaatctg aggcacctgg
    82261 tataatagat agaaggtctg tttatgaacc attacaaaca ggaatcaaat caatagattc
    82321 aatgatacca attggtagag gtcaaagaga gttaataata ggtgacagac aaactggtaa
    82381 aacatctata gttattgaca ctatactaaa tcaaaaagga aaagatgtta tctgtatata
    82441 tgtagcaatt ggacaaaaac gttctactat agctcaatta gttagctctt tagaaaaagg
    82501 tggagctttg gattatacaa tagtagtttc agcaacagca tctgaatcag caccacttca
    82561 atatatagca ccatatgctg gagcagctat gggtgaagaa tttatgtaca atgggaaaca
    82621 tgtacttata gtgtatgatg atttaagtaa acaagctgtt gcatatagag aaatgtcatt
    82681 gttacttaga agaccaccag gacgtgaggc atatcctgga gatgtattct atttacattc
    82741 aagattactt gaaagagcag ctaagttatc tgatgaattg ggtggaggtt caatgactgc
    82801 cttgcctata atagaaactc aagctggtga cgtttctgca tatataccaa caaatgttat
    82861 atctataaca gatggtcaaa tatacttaca accagagtta ttctattcag gtgtaagacc
    82921 agcagttgac cctggtatat cagtatcaag ggttggtggt tctgcgcaaa ttaaagcaat
    82981 gaaaaaagtt gcaggaacat taaaacttgc atattcacaa tatagagaac ttgcagcatt
    83041 ctcacagttt ggttctgact tagatgaaga tactaaaaag agacttgctc aaggtgaaag
    83101 aatcgttgag atattaaaac aaggtgagca tcaaccaata aaagttgaaa atcaagttat
    83161 gataatatat gctgttataa ataatcattt agaggatatt ccgatagata atatagctag
    83221 atttgaatca gaattgtatg catttgtaga taataattat ccggaaatat caagaaaaat
    83281 attaggtgga gaagacttca ctcatgattt aacagatgca ataaatgaat ttaaagaaaa
    83341 gtttgttgtt gaagtataat cctttttaaa aaaggaggta aattaattgg caggagctgg
    83401 aatcaaagca atcaaaacac gtatgggaac tgttgaaagt acaaagcaaa taactaaagc
    83461 aatggaatta gttgcatctt ctaagcttag aaaagcaaaa gaaaaggctg aagattcaag
    83521 agaatatttt aatactttat acaatacagt aaaagatatt gcccaaacaa cacgtggaat
    83581 tagaaatgaa tttttaaaag aaagagaagt aaaaaataaa tgttatgtag tagtagctgg
    83641 agacagagga cttgcaggtg gatacaattc caatgtatta aaggaatctg tctctcatat
    83701 gaaaggtaaa aaggaaacag tgattactgt tggaaagaaa gcacatgaat ttttttctaa
    83761 aagaaactac aatatagcaa aagatataaa tagtgttgaa gcttgtggat atgaagatgc
    83821 gacagaaatt tcacaaacta ttattgacct gtataaaaaa ggtgaagtag atgaagttta
    83881 tattgcttat acaaaattta aatctgcttt atcacaagaa gttgaaattt tgaaattgct
    83941 tccattagtc tttgaaaaag atacagacga acaaggaatg gcagtaaaag aagaaaaaca
    84001 aaatagatca aaagtacaat atataccatc agcagaagca gttttaagtt atattgtacc
    84061 tcagtttata tcaggtacag tatatggtgg aattttggaa tcttttgcat cagagcaagg
    84121 tgctagaaga actgcaatgg aatcagccac agacaatgcg aatgaaatgc tatctaattt
    84181 agagttaagt tataacagag caagacagtc agctgtaact caagaaataa cagagatagt
    84241 tggtggagtt gaagctctaa aatagggagg ttaggaaatg gcaaatgtag gtaaagtagt
    84301 acagattgta ggagctgtac tagatgttaa gtttgatagt gaacaaagcc tacctaactt
    84361 attaaatgcg ttagtaataa agttaggaga taaagaaata gttgcagaag ttgctcaaca
    84421 tataggtgat gatactgtaa gatgtatagc tatgagtgca acggacggac ttgtaagagg
    84481 tatggaagtt gtagatacag gagggccaat aagtgtccct gttggagatg agactttagg
    84541 tagaatattc aatgttcttg gaaaaccagt tgatgggaaa ccagctccaa aatctgcacc
    84601 taaattacct atacatagac cagcaccggc gtatgatgaa ctagaaacta cagcagagat
    84661 actagaaact ggtattaagg tagttgactt actagctcca tatctaaaag gtggaaaaat
    84721 aggtctattt ggaggagcag gagtaggaaa gacagttcta atacaagagc ttataaacaa
    84781 tattgctaag caacatggtg gtatttctgt attttcagga gtaggagaaa gaacaagaga
    84841 aggtaacgac ctttatggcg aaatgagtga gtctggagtt ataaataaaa cagctctagt
    84901 atttggtcaa atgaatgaac cacctggagc gagaatgaga gttgctttaa ctggacttac
    84961 aatggcagaa cattttagag atgagcaagg acaagacgtt ttacttttcg ttgataatat
    85021 attccgtttc acacaagctg gttcagaagt ttcagcactt ctaggacgta tgccatcagc
    85081 tgttggttat cagccaacat tagctactga aatgggtgca cttcaagaga gaataacatc
    85141 aactaagaaa ggttcaataa catctgttca agcagtatat gtaccagcag atgacttaac
    85201 tgacccagca ccagctacaa cattctctca cttagatgca aaaacagttt tatcaagaca
    85261 aatatcatca ctgggtatat atccagcagt tgaccctctt gaatctacat caaggattct
    85321 tgaccctagt atagtaggaa aagaacatta tgaagtagct agaggtgtac aatcaatact
    85381 tcaaagatat aaagaacttc aagatataat tgctatactt ggtatggatg aattatctga
    85441 tgaagataag ttaatagttg cacgtgctag aaagatacaa agattcttat ctcaatcatt
    85501 cacagttgct gagcaattta caggaaatcc aggtcaatat gttcctgtta aagagactgt
    85561 aagaggattt aaagaaattc ttgaagggaa acatgatgac ttaccagagt cagcattctt
    85621 atttgtagga acaatagaag acgctgttag aaaagcgaag ggaagtatgt agtcatggcc
    85681 agtgaatttt cattgaaagt tgtaactcca agtaatactt tttatgatgg agatgttgaa
    85741 atgatagtag ttagaactac aaaaggagac aaaggggtgt tgaaaggtca tataccattt
    85801 gtttcaggta tacctgtagg aactttaaag ataaaaaaag agggaagttt taaagaggcg
    85861 aaaatagcag aaggattcat taatgtaact caagataaaa ctgtcatatt gacagaatct
    85921 gctgagtgga tttaataaat taatttagag tataaaaagt cattttgacc aaaaaaactt
    85981 ttgggtaaaa tggctttttt gtgttttggt gttaataaaa taacgataaa attgtaagtt
    86041 tttagtgata ataaattcac aaaatgttta aatttactgc caaattatgt tgtaattaat
    86101 aagataaaga agatttagat agcttttatg taagtgaaaa agtcttcata taagaaatac
    86161 atataaaatt tttataaaat ttaaaaaatt tgcttagttg tgta
//
LOCUS       DAMJWO010000006        72240 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.007, whole genome shotgun sequence.
ACCESSION   DAMJWO010000006 DAMJWO010000000
VERSION     DAMJWO010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 72240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72240
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.007"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(121..894)
                     /locus_tag="PC366_000467"
     CDS             complement(121..894)
                     /locus_tag="PC366_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HDF2576022.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
     gene            complement(894..1280)
                     /locus_tag="PC366_000468"
     CDS             complement(894..1280)
                     /locus_tag="PC366_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2576023.1"
                     /translation="MEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVAVSEACTN
                     AIKHSKDDVFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLGLFIIKTL
                     MDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            complement(1305..1622)
                     /locus_tag="PC366_000469"
     CDS             complement(1305..1622)
                     /locus_tag="PC366_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HDF2576024.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVKKIFTITGLDKIFK
                     VEG"
     gene            complement(1634..1894)
                     /locus_tag="PC366_000470"
     CDS             complement(1634..1894)
                     /locus_tag="PC366_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HDF2576025.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            complement(1894..2190)
                     /locus_tag="PC366_000471"
     CDS             complement(1894..2190)
                     /locus_tag="PC366_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF2576026.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            complement(2259..4685)
                     /gene="gyrA"
                     /locus_tag="PC366_000472"
     CDS             complement(2259..4685)
                     /gene="gyrA"
                     /locus_tag="PC366_000472"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HDF2576027.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDIAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKIGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKNEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            complement(4705..6606)
                     /gene="gyrB"
                     /locus_tag="PC366_000473"
     CDS             complement(4705..6606)
                     /gene="gyrB"
                     /locus_tag="PC366_000473"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003226808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HDF2576028.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKIYKQTYEKGLPTSKLEVVGESQ
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            complement(6607..7722)
                     /gene="recF"
                     /locus_tag="PC366_000474"
     CDS             complement(6607..7722)
                     /gene="recF"
                     /locus_tag="PC366_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HDF2576029.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            complement(7740..7946)
                     /gene="yaaA"
                     /locus_tag="PC366_000475"
     CDS             complement(7740..7946)
                     /gene="yaaA"
                     /locus_tag="PC366_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HDF2576030.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVKIEGTKIKVL"
     gene            complement(8083..9189)
                     /locus_tag="PC366_000476"
     CDS             complement(8083..9189)
                     /locus_tag="PC366_000476"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HDF2576031.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            complement(9431..10753)
                     /gene="dnaA"
                     /locus_tag="PC366_000477"
     CDS             complement(9431..10753)
                     /gene="dnaA"
                     /locus_tag="PC366_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HDF2576032.1"
                     /translation="MMDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILL
                     APSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYP
                     NLNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHH
                     IVSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERT
                     QEEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIA
                     ILRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEA
                     LKDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTD
                     LSLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            11409..11546
                     /gene="rpmH"
                     /locus_tag="PC366_000478"
     CDS             11409..11546
                     /gene="rpmH"
                     /locus_tag="PC366_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HDF2576033.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            11624..11968
                     /gene="rnpA"
                     /locus_tag="PC366_000479"
     CDS             11624..11968
                     /gene="rnpA"
                     /locus_tag="PC366_000479"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HDF2576034.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            12000..12251
                     /gene="yidD"
                     /locus_tag="PC366_000480"
     CDS             12000..12251
                     /gene="yidD"
                     /locus_tag="PC366_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HDF2576035.1"
                     /translation="MNKIIYILKEISRYLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFVKGMYLTIRRLLKCHPFHPGGYDPLK"
     gene            12283..12990
                     /locus_tag="PC366_000481"
     CDS             12283..12990
                     /locus_tag="PC366_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDF2576036.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYVLAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            12959..13588
                     /locus_tag="PC366_000482"
     CDS             12959..13588
                     /locus_tag="PC366_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HDF2576037.1"
                     /translation="MRKSLKLIKSKSKEEAISKAIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKTKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            13700..15079
                     /gene="mnmE"
                     /locus_tag="PC366_000483"
     CDS             13700..15079
                     /gene="mnmE"
                     /locus_tag="PC366_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HDF2576038.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGERALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNILDNENIIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKEKTDELKKEIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVEKSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            15174..17069
                     /gene="mnmG"
                     /locus_tag="PC366_000484"
     CDS             15174..17069
                     /gene="mnmG"
                     /locus_tag="PC366_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HDF2576039.1"
                     /translation="MIKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSI
                     ALMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQAD
                     KFKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVY
                     LNSKIYMGEVAFYEGPNALGYAKYLTDSLVELGLRMRRFKTGTPARVHRDSIDFSVMS
                     LQEGDEKVTPFSFMNENIEKKQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPR
                     YCPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLEN
                     CKIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINA
                     VRKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLT
                     QKGYDIGLVKKDRYERFLNKKAAVDKEFERLKNERVTPKEVNSLLEEKGATPIKVGIS
                     LYEFLKRPEVTYELLEELGKGAGEDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLE
                     NKKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQVRR
                     TRGGKGE"
     gene            17062..17781
                     /gene="rsmG"
                     /locus_tag="PC366_000485"
     CDS             17062..17781
                     /gene="rsmG"
                     /locus_tag="PC366_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HDF2576040.1"
                     /translation="MNNIELLKNGIEGFNIDTNDSMLEKFKIYREILVEWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDSLELTLLDS
                     LNKRINFLEEVSRVLELDNITFIHGRAEDFGKNEDYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEVDLNHNILVFKK
                     VMETPVKYPRKAGRPAKNPIK"
     gene            17956..18741
                     /gene="noc"
                     /locus_tag="PC366_000486"
     CDS             17956..18741
                     /gene="noc"
                     /locus_tag="PC366_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HDF2576041.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKVQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            18876..19649
                     /locus_tag="PC366_000487"
     CDS             18876..19649
                     /locus_tag="PC366_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDF2576042.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENVDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            19651..20514
                     /locus_tag="PC366_000488"
     CDS             19651..20514
                     /locus_tag="PC366_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HDF2576043.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETSEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLSDSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            20547..21689
                     /locus_tag="PC366_000489"
     CDS             20547..21689
                     /locus_tag="PC366_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDF2576044.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKALEKRGIENTVVKCDYEGFLDYEDLEKSIKSNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYDIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVSDIKIYGPKDSKKRASVIALNIGDMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(21823..22398)
                     /locus_tag="PC366_000490"
     CDS             complement(21823..22398)
                     /locus_tag="PC366_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HDF2576045.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGSDTSKKETKSNTNVEQ
                     PKEENNTEKEVPNNKAKPTPKEETKTQSATIYSFDVDKTDLIENKVDLNKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAETLMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            22658..23950
                     /locus_tag="PC366_000491"
     CDS             22658..23950
                     /locus_tag="PC366_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2576046.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSENKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEVTLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            24055..24657
                     /gene="yedF"
                     /locus_tag="PC366_000492"
     CDS             24055..24657
                     /gene="yedF"
                     /locus_tag="PC366_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HDF2576047.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDNLEEGVVVTIVDNETAKENI
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNVVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            24730..24993
                     /locus_tag="PC366_000493"
     CDS             24730..24993
                     /locus_tag="PC366_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HDF2576048.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILVENNVDIKGIYCISKLENGSKEVEKLD"
     gene            25008..25193
                     /locus_tag="PC366_000494"
     CDS             25008..25193
                     /locus_tag="PC366_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HDF2576049.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTKCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            25296..26492
                     /locus_tag="PC366_000495"
     CDS             25296..26492
                     /locus_tag="PC366_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2576050.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDSDGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLEKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            26706..26984
                     /locus_tag="PC366_000496"
     CDS             26706..26984
                     /locus_tag="PC366_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HDF2576051.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            27021..27455
                     /gene="ssb"
                     /locus_tag="PC366_000497"
     CDS             27021..27455
                     /gene="ssb"
                     /locus_tag="PC366_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2576052.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            27474..27701
                     /locus_tag="PC366_000498"
     CDS             27474..27701
                     /locus_tag="PC366_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HDF2576053.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            27844..28164
                     /locus_tag="PC366_000499"
     CDS             27844..28164
                     /locus_tag="PC366_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HDF2576054.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            28172..29128
                     /locus_tag="PC366_000500"
     CDS             28172..29128
                     /locus_tag="PC366_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HDF2576055.1"
                     /translation="MNNKIRLSKAMSIIVLAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFADISYALNICIMYSLPGIVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNSFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSKLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            29139..31133
                     /locus_tag="PC366_000501"
     CDS             29139..31133
                     /locus_tag="PC366_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HDF2576056.1"
                     /translation="MSNKQTFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRRHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            31134..31583
                     /locus_tag="PC366_000502"
     CDS             31134..31583
                     /locus_tag="PC366_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HDF2576057.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRSLGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            31602..32930
                     /gene="dnaB"
                     /locus_tag="PC366_000503"
     CDS             31602..32930
                     /gene="dnaB"
                     /locus_tag="PC366_000503"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HDF2576058.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            33135..33443
                     /locus_tag="PC366_000504"
     CDS             33135..33443
                     /locus_tag="PC366_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576059.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKYEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            33525..34814
                     /locus_tag="PC366_000505"
     CDS             33525..34814
                     /locus_tag="PC366_000505"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HDF2576060.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKTDNISTENIKISDRA
                     HVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNKIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
     gene            35140..35215
                     /locus_tag="PC366_000506"
     tRNA            35140..35215
                     /locus_tag="PC366_000506"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35173..35175,aa:Lys,seq:ttt)
     gene            35222..35296
                     /locus_tag="PC366_000507"
     tRNA            35222..35296
                     /locus_tag="PC366_000507"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35255..35257,aa:Glu,seq:ttc)
     gene            35301..35376
                     /locus_tag="PC366_000508"
     tRNA            35301..35376
                     /locus_tag="PC366_000508"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35334..35336,aa:Val,seq:tac)
     gene            35410..35484
                     /locus_tag="PC366_000509"
     tRNA            35410..35484
                     /locus_tag="PC366_000509"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35442..35444,aa:Thr,seq:tgt)
     gene            complement(35867..36859)
                     /locus_tag="PC366_000510"
     CDS             complement(35867..36859)
                     /locus_tag="PC366_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2576061.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKEKLLSESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(36868..37926)
                     /locus_tag="PC366_000511"
     CDS             complement(36868..37926)
                     /locus_tag="PC366_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HDF2576062.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNGEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            38051..39514
                     /locus_tag="PC366_000512"
     CDS             38051..39514
                     /locus_tag="PC366_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HDF2576063.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNIDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIDDKHDNKKMLYEIEAENVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            39616..40413
                     /locus_tag="PC366_000513"
     CDS             39616..40413
                     /locus_tag="PC366_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2576064.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            40426..42528
                     /locus_tag="PC366_000514"
     CDS             40426..42528
                     /locus_tag="PC366_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC/EAL
                     domain-containing protein"
                     /protein_id="HDF2576065.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSVLFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVIMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTITSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKIGSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEKEI"
     gene            42596..43075
                     /gene="rlmH"
                     /locus_tag="PC366_000515"
     CDS             42596..43075
                     /gene="rlmH"
                     /locus_tag="PC366_000515"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HDF2576066.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKDKEGKKILGKIKHNSYVIVLAIDGKGLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSKMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            43224..43535
                     /locus_tag="PC366_000516"
     CDS             43224..43535
                     /locus_tag="PC366_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2576067.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            43583..43900
                     /locus_tag="PC366_000517"
     CDS             43583..43900
                     /locus_tag="PC366_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2576068.1"
                     /translation="MDEKIIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SKEVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
     gene            44113..44814
                     /locus_tag="PC366_000518"
     CDS             44113..44814
                     /locus_tag="PC366_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2576069.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKKTIS
                     IEKIINDTNSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            45038..46339
                     /locus_tag="PC366_000519"
     CDS             45038..46339
                     /locus_tag="PC366_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2576070.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKATLDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            46476..47570
                     /locus_tag="PC366_000520"
     CDS             46476..47570
                     /locus_tag="PC366_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDF2576071.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMVSKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNEYQVVFNVVAKEKTSEVEKIIMVNEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNKNIFKRGDVVIGNDDFGKYKGELQLILQDCTDERK
                     NKVGRIKEDEIILLDFIEPWSKFKIILEGE"
     gene            47572..48705
                     /locus_tag="PC366_000521"
     CDS             47572..48705
                     /locus_tag="PC366_000521"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HDF2576072.1"
                     /translation="MKIDILIKCGKTVDKSIIDIAILDDKIIEVKNHIDDSKYQAKQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGEFY
                     EDTKKYKTNVYALINIAKQGITSQDELSNMMNIDEYELKNAVRKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKRIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEAKERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIIDKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGNSIEENE"
     gene            48723..49832
                     /locus_tag="PC366_000522"
     CDS             48723..49832
                     /locus_tag="PC366_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HDF2576073.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFL
                     IIEELVNKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTIKGVSASITRDSAGREILRGEINFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDNIYNRIKNIVES"
     gene            49897..50637
                     /locus_tag="PC366_000523"
     CDS             49897..50637
                     /locus_tag="PC366_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HDF2576074.1"
                     /translation="MNCIPQYYKNRVCLNVLAGSIKNAKEVYDACDGHVLVGVLSKNY
                     STVEAAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQNDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGDTKVEDIGVLYKIMKELLG"
     gene            50642..51634
                     /locus_tag="PC366_000524"
     CDS             50642..51634
                     /locus_tag="PC366_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDF2576075.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYIITGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEEMDIVHICGIAMQLTDSVKKIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNDYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIDIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGAGDGYVA
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNSLVSTGHVLRLMNNEKIDILR"
     gene            complement(51821..52702)
                     /locus_tag="PC366_000525"
     CDS             complement(51821..52702)
                     /locus_tag="PC366_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2576076.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVSSNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            52975..54363
                     /locus_tag="PC366_000526"
     CDS             52975..54363
                     /locus_tag="PC366_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576077.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPNNPVEIGKWWRPDQYADGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFMPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKAGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            54391..55344
                     /locus_tag="PC366_000527"
     CDS             54391..55344
                     /locus_tag="PC366_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDF2576078.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEAIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLESGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIEPLTKEKQAGVSLG"
     gene            55404..55628
                     /locus_tag="PC366_000528"
     CDS             55404..55628
                     /locus_tag="PC366_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576079.1"
                     /translation="MNEKPSFKQIEIILAVIFLVLTYYKIGLTPAFIVIFIPLYLSYF
                     AVSMIVNQIAIKLLEIRQAREATNYNIGNG"
     gene            55621..56133
                     /locus_tag="PC366_000529"
     CDS             55621..56133
                     /locus_tag="PC366_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HDF2576080.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQKDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTIMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     ILSKDKKKGN"
     gene            56165..57019
                     /locus_tag="PC366_000530"
     CDS             56165..57019
                     /locus_tag="PC366_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HDF2576081.1"
                     /translation="MAMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDVENKRVHENAESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVS
                     ELWFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            57586..59673
                     /locus_tag="PC366_000531"
     CDS             57586..59673
                     /locus_tag="PC366_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2576082.1"
                     /translation="MVVDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKIN
                     DMLKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLF
                     INMEDISINHFINSIKVSRSTVNLDFKDLIPELEKKNIKVKNNRINGYYIVGNEMEIR
                     RVLIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLIEF
                     IYIFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPYNIM
                     YISAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFR
                     PAYYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHF
                     ATLFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENIS
                     EPVDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIYLRQPKIDEV
                     MDIIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNW
                     EEAIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAI
                     GIATLDSPIEFGNNENDPVKYVFCLSAIDNNSHLRAMSELVELLEEDEFFKVLDSAKE
                     AKEIIDFIKTHEL"
     gene            59688..59975
                     /locus_tag="PC366_000532"
     CDS             59688..59975
                     /locus_tag="PC366_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2576083.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            60002..61273
                     /locus_tag="PC366_000533"
     CDS             60002..61273
                     /locus_tag="PC366_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HDF2576084.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            61331..61930
                     /locus_tag="PC366_000534"
     CDS             61331..61930
                     /locus_tag="PC366_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2576085.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKTLKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIVLQSLSVVLQYAKGLNTQQYLKWHPAGSLGKSIREGI"
     gene            61935..62840
                     /gene="dapA"
                     /locus_tag="PC366_000535"
     CDS             61935..62840
                     /gene="dapA"
                     /locus_tag="PC366_000535"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDF2576086.1"
                     /translation="MKYKGIICAMITPFDEKQNINSQATCKLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVIDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPGKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKAYIEVTQNENFSVFSGSDSLILDSLKAGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKAQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            62946..63578
                     /locus_tag="PC366_000536"
     CDS             62946..63578
                     /locus_tag="PC366_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HDF2576087.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGEILCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGINLENLHIWLENGVDVCGFGGLLTKGTIEDITENAKKIREIIKNIREI"
     gene            63993..66164
                     /locus_tag="PC366_000537"
     CDS             63993..66164
                     /locus_tag="PC366_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HDF2576088.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNDTTSISVMF
                     KDYKKLNKNYSKWIKDIADENNVAISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFPN
                     TNSNEFISNINTNNSNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNED
                     TINKILRELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVS
                     REASILRLNGYSKLDIIARVIKNIFRIMILSSVTALLIYIIYILKLNIGVRACLYFAM
                     FSIICILINILISILIVGFNSRSSKYVLSLNGKKSYGFVNIMHFTLKIVFVSFLILSI
                     NNCILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLV
                     EEKDAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGK
                     EIFNLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRELNKT
                     KKSDLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIIDIDNIDDSFYLSYISRCV
                     YFNSKKLDALADISNIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIA
                     ISNLMITYNIVASYYERNKYKLYIKKIFGYSTTARSMLLIVSLILTNIIPIGIISTRV
                     DLSNNIILFGLLILVIEVIVSIVLDKIISNSSFNKIIKGEH"
     gene            66169..66786
                     /locus_tag="PC366_000538"
     CDS             66169..66786
                     /locus_tag="PC366_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2576089.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNEKINYALESVGLRKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKNLNKNGKTIVFVTHDLELSEQADRVIKL"
     gene            66975..67319
                     /locus_tag="PC366_000539"
     CDS             66975..67319
                     /locus_tag="PC366_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HDF2576090.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGAEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            67889..68755
                     /locus_tag="PC366_000540"
     CDS             67889..68755
                     /locus_tag="PC366_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDF2576091.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPIDK
                     ESGKPCINLQPDFKCSVHNSLMKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSPELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMSPEQIINLD
                     IISHRTKVNLLLSQASESVMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRSTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            68868..69272
                     /locus_tag="PC366_000541"
     CDS             68868..69272
                     /locus_tag="PC366_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HDF2576092.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEAIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            69450..69899
                     /locus_tag="PC366_000542"
     CDS             69450..69899
                     /locus_tag="PC366_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2576093.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(70055..70432)
                     /locus_tag="PC366_000543"
     CDS             complement(70055..70432)
                     /locus_tag="PC366_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2576094.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLDSNPNNPIMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            70694..71611
                     /locus_tag="PC366_000544"
     CDS             70694..71611
                     /locus_tag="PC366_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HDF2576095.1"
                     /translation="MVNMNIIEIRSDKIYKKIMDAPINKKEDIYRYELMKPFEFKWKC
                     MNVPIVARQKGGYDVIIASEMLGVLSPKDIDEKQKKNINVLSADKIWGTCKETIENSI
                     NAFIKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINR
                     LPVLIAHECNHNIRFQFIEWNNNITLEEMMINEGLAENFATWMFGEEMLGPWVSRTDI
                     ETLNTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKY
                     YLEKTNKSIIEATLLPYSEIIETVKEFWE"
     gene            72094..>72240
                     /locus_tag="PC366_000545"
     CDS             72094..>72240
                     /locus_tag="PC366_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HDF2576096.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGIY"
BASE COUNT        27527 a         8632 c        12007 g        24074 t
ORIGIN      
        1 atataaatta acctactgtt taattttcaa tgttcgtgtt tatttcttgt tccttttttc
       61 aaggacaagt aatactatac catctttaaa acagtaggtc aatacttttt ttatattttt
      121 ttataaattt ttttcatatt cttttttcag cttctctact acctttttct ctagtctaga
      181 aacagtcatc tgtgatatcc ctagttcttt agctatacta gattgtgttt tatcaaagaa
      241 aaatctatct ttaaaaattt taacttctaa ttcatttaaa gtttcaataa acttattaat
      301 aaaatcttca tactctatac ttccaaagtt accttcttct tttccaatct tatcaataag
      361 agttatatct ttatcctctg aatcatcatt acttgatgaa tccaaagaca ttggttgata
      421 tccataagaa gcctccatag cctctaaaac atcttcttca ctaacgccta tataatcagc
      481 tatatctttt acctttggat gcttcttatt ttcttgttct aatttaatct tcgcatcact
      541 tatctttttg cttaattcct gtattcttct tgggactcta agtgtccata ccttatctct
      601 aaaatacttt tttatttctc ctactatagt tggtgtcgca aagctggaga actcaaatcc
      661 tttctcaaca tcatatctat caatagcata aattaatgcc aatgaagcaa cttgatatat
      721 atcttcaaaa tcaacacctt tgtttatata cttcttagct aacaatcttg ctaaatacag
      781 atgtctttca ataagaatat ttctaatgtc tacattttta tttttattat ataaattaaa
      841 tagctctttt gtatccatat ttaggtaatg tgtagcatta gctacatttt tcattaaata
      901 tcaactccta aatatttagt catttttatt tttgtccctt gattatgttc tgattcaata
      961 tctacatcat ccattaaagt tttaattata aacaatccaa gaccactctc ttttggattc
     1021 tctaaatctg gtgtacttat tgagctaaca tcatatcctt ttccattatc ttgaatttct
     1081 atattaattg cattatctaa aatattaaat actatattaa acacatcatc tttactgtgt
     1141 tttattgcat ttgtacatgc ttcagatact gctaccttta tatcttctat atcatctatt
     1201 ggaaaaccca tcttattggc aattccagat gctgttaatc ttattatact aacataatct
     1261 ggatttgtag taatttccat ctttatagtc tcacaagcca aagtttatcc ctccacttta
     1321 aatattttat ctagacctgt tatagtaaaa atctttttta cgttactctt aggatttact
     1381 atgtatatct ctttttcatt tatttttaat ttttttaata cacctatcat agctcctaag
     1441 cctgttgagt ctatataatc taaatcttta agattaatct ttacatctaa catatttttt
     1501 tctattaaag catgtaaatg ttcctttagt ttatctgctg tagaaacatc aagttctcca
     1561 tcaagacaaa cattccaaaa tttattttgt gaatctaaat ttgaatcaat attcatagac
     1621 atgtaaaaac ctcctatttc cttttaataa ttttaaatat atttcctata ctcaatattt
     1681 tattaattac ataaactata tcatctattc cctttgatat tgatgatgca ttttcaacaa
     1741 tatcttgtat atgtctttca ttataatcta caatcttata tgccttttca acaaccttat
     1801 ttatgctgtt tagagtttta gctaaataaa ttgctactat aagagcagag cttcctacta
     1861 acactgctcc aatttgccac ccccatgcat tcattagtta acatctccct catcatcaaa
     1921 gcttttactt attactatat cttcttctga aatctttata tcttcttcat tattatcatc
     1981 gtccactaaa tttattattc tctctttaac atcattaaat gtttcatgta gaacttcttt
     2041 tggattttct ttgacatcat taaacttctc ttttgtttct tttcttagtt cagaaccttt
     2101 tttaggtgca aaaaacatac caaatataaa ccctaaaata gctcctaata ataaaaatcc
     2161 acctttttta caacttcttt tattgcacat aacaattact cctttcaatt ttaaattttt
     2221 atctaactac attatacaaa aagaatagga tatttatcct attcttcttc aatatttatt
     2281 ttggcaatcg aaactacatt gacttcatca ttcgtcttca ttaatttaac accacttgta
     2341 actcttccaa acagtgatat ttcattgact cttattctaa taagaactcc atcagaattt
     2401 ataatcatta tctcatcatc ttcgttgacc atatctgcac ctacaattgt accagttttt
     2461 tcagatatat tataagtttt aattccttta ccagctctta tttgacttct atactcttct
     2521 atatttgttc tctttccaaa accattctta cttacaacta acacatctgt acctttactg
     2581 caaaggttca tagacacaac aaaatcttct ttacttaaag ttataccttt tacacccatt
     2641 gctgttctac ccatatatct tatatcattt tcatcaaatc ttatagacat accttcttta
     2701 gttactaaaa gtacttcttg ttttccatct gtaagttcta ctccaataag ctcatcatca
     2761 tctcttaaac ctatagcaat aagaccagat ttatttatat ttttgaactc ttctctctta
     2821 gtctttttaa caataccttt tttcgttgca agtaataaat attcattttc atcattacca
     2881 tcaataggta ttagagtagc aattttctca tctgctgaca attgaagtaa attcactata
     2941 gcagtacctt tagcctgtct cttaccttct ggtatttcat atgcatttaa tttaaatact
     3001 ctacctttat ttgtaaagaa taatagtcta ctatgagtag ttgtagttac caagtgcctt
     3061 acaaaatctt cttctctagt tgtaagtgct gaaatacctc ttccacccct tttttgactc
     3121 ttataagtat cagatggaag cctttttata tatccaaagt gagtaagagt tattgctatt
     3181 tcttcatcac ttataagatc tctcatatct atttcgcctt cagcatgtct tatttctgtt
     3241 cttctctcat cagagtaatt ttcttttatt attgtaattt cattctttat tacatttaaa
     3301 agtaatcttt catcagctaa aatttctttt aatctattta tcttcttgat taaatcttca
     3361 tattcagctt ctatcttatc tctttctaaa cctgtaagtc tttgaagtct catatctaat
     3421 atagcttgtg cttggatttc agttaatttg aatttttcta ttaaacctat cttagcttct
     3481 tgcccagtct ttgaagctct tatcaagctt ataacagcat ctatattatc taaagcaatc
     3541 tttaatcctt ctaaaatatg tgctcttgct tcagctttat ttagttcaaa tttagttctt
     3601 cttgtaacaa catcttcttg atgtttaata taatgatata atatttgttt aagatttaaa
     3661 actcttggct gaccatctac aagtgcaagc attattatac taaaagtatc ttccatttga
     3721 gaatgtttat acaaattatt taatactata ttagcattag catccctctt taattctata
     3781 acaattctca taccatttct attactttcg tctcttaggt ctgatatacc ttctattctc
     3841 ttttctttaa ctaactctgc tattctttca accagtttag ccttatttac ttgataaggt
     3901 atttctgtaa ctattatttg ctgttttcct tttggtagtt cttctataaa agctctagac
     3961 ctaactttaa cttttcctct tccagttctg tatgcttctg ctatactttc ttttcccatt
     4021 ataattgcag ctgtagggaa atctggtcct tgaacaaatt ttattaaatc atctacacta
     4081 cactctggat tatctatcaa atatacagtt gcatcaatta cttctgctaa attatgtgga
     4141 ggtattgaag ttgccatacc aacagctata ccatttgagc catttactaa taaattagga
     4201 tatctagctg gcaatactga aggctctttt aacgactcat caaagtttgg tttaaagtct
     4261 acagtttcct tttcaatatc tctcagtagt tctaatgata atttactcat tttagcttct
     4321 gtataacgca tagcagctgg tgaatcccca tcaacagaac caaagttacc atgaccatct
     4381 actaaaagtg ctctagttga aaaatcttgt gccattctta ccatagcata ataaacagca
     4441 atatctccat gaggatggta cttacctaaa acgtccccaa caatacgagc tgacttcctg
     4501 tatggtttat ctggagttaa atttaactca ctcattgaat ataatattct tctatgaact
     4561 ggctttaaac catctctaac atcaggaaga gcacgtccag ctataacact cattgaataa
     4621 tcaatatacg attttttcat ttcttccgct atttcaatag ggagtatttt gttattttct
     4681 tccatgtata ctaatcccct ctctctatat atctaaattt ctaacaaatc ttgcattttc
     4741 ttctataaat tcttttcttg gagcaacctt atcacccata agcattgaaa atacttcatc
     4801 tgcaattgca gcatcttcta cagtaacttg taataaagtt cttgtctcag gattcatagt
     4861 tgtttcccat aattgctctg cattcatctc tccaagacct ttgtaccttt gaagttcaac
     4921 accatttctt ccaatttcat ctaataagat atttaactct ttatctgagt aaacataatg
     4981 ttccttcttt tgctttgtca ctttatataa aggtggctgt gctgcataaa catacccctc
     5041 atctataaga ggtctcatat atctaaagaa gaatgttaat aataaagttc ttatatgggc
     5101 tccatctaca tcagcatcgg tcataattat aattttatga tacctagcct tatctatatc
     5161 aaaatcttct ccaataccac aaccataagc tgttatcata ttttttattt catctgaaga
     5221 tagtatccta tctagtcttg atttctcaac attaagtatt ttccctctta atggaagtat
     5281 agcttgacta tttctatctc taccttgttt agctgaacct cccgctgaat ccccttcgac
     5341 taagaatatt tcacttttag atggatcttt ttctgcacaa tctgcaagtt ttccaggtaa
     5401 agatgtactt tctaatacac tttttctcct tgttaattct cttgcttttt ttgcagcttc
     5461 tctagctctt tgtgctctta aagctttatc aactatgatt cttgctgttg atgggttttc
     5521 ttctaggaaa gaccccagtt catcaactgt tacactatca actatacctc tcataaagct
     5581 attacctagc tttgttttag tttgaccttc aaattgaggt tctggtaatt taactgatac
     5641 tactgctgta agaccttctc ttatgtcttc accaagtagg ttaacatcat tttcctttaa
     5701 aaatttattt ctcttagcat aatcatttac agttttagta agagctgctt taaatccact
     5761 taaatgagaa ccaccttcgt gtgtatttat attgtttgca aaagaatata tgttctctgt
     5821 ataaccatct gtatattgca tagctagttc aacaaaacaa tcatcaacct ttttatctat
     5881 ataaactatg tcatcatgta taccagttct agatttattt aaatacttaa tatattctac
     5941 caaaccacct gtatagtgaa attcttttct tttttcttgt ccttctcttt tatcttcaaa
     6001 tactattttt attcctttat tcaagaaaga aagttctcta agcctatact ccaatgtttc
     6061 atatttaaac tctatttcat caaatattgt ctcatctggc ataaattgaa tcattgttcc
     6121 tttatcttga gattctccaa ctacttcaag cttagatgtt ggtaatcctt tctcatatgt
     6181 ctgcttatat atctttccgt ttaaataaac ctctgctacc atccattttg acaatgcatt
     6241 aactacagaa acaccaactc catgaagacc tccagatact ttatatcctc cgcctccaaa
     6301 ctttcctcct gcatgaagat tagttaatac tgtttctaaa gttgatttac cagttttagg
     6361 atgtatttca acaggtatac ctcttccgtt atcttttact aaaacactgc catcttcatt
     6421 aatagataca tatatgtctg aacaatatcc ttgtaaagcc tcatctatac tattatctac
     6481 aacttcataa actaagtgat gtaaacctct agggcttgta ctaccaatat acatacctgg
     6541 tctttttcta acggcttcta atccctctaa tacttgtatc tgacttgcac cgtattcttg
     6601 tttcatttaa tttcctccat tctctatgct aataacatcg ccattttcaa tattaaatat
     6661 tgtaacattt ttttcatcaa atattttttt atgtgaaact tcagcacttg ttataaacat
     6721 ttgaacattg cttaaattat ttactaaaag tttttgtctt gcttcatcta actcactaaa
     6781 aacatcatct aaaattaata ctggatattc ttcaacttca ttttttatta attctatctc
     6841 tgataacttt aatgatattg aagcagttct ttgttgacct tgtgaaccaa aaagtcttgc
     6901 atctaaatca tttatgaata tatttaagtc atctttgtgt ataccatatc tggtagtctt
     6961 agattctata tcattaggtc tattcgatga caacttggct aaaaatttat tatatactgt
     7021 atctatagta tcttcatcag ttatatttat ttgattttta tatcgaattg ataatctttc
     7081 aactccatta gtcaaattca tatgcatatt ttcagatata ttagctatct tttttataaa
     7141 gtctctacgc aaaatataaa tataacttcc atactttgct aacgtatcat catatacatc
     7201 taataaagct tcatcaacat gtatattttt aagcacccta ctcctttgag aaagtgtttt
     7261 attataattg gtaagatatt tataatattt aggtataatc tgactaatct ctttgtctat
     7321 aaatgccctt ctttctttag gaccctcttt aaccaacctt aaatcttcag gagaaaatat
     7381 aacaacattt aagttgccaa gtagttcttg tatcttttgt aaaggaactt tatttattct
     7441 tatccccttt ttatcttttc caataattag ctctattaga ctatatttat tatattttga
     7501 aaaacttcct ccaatgtata agttttcact attaaatcta accatttctt tatctttgtt
     7561 agtcctaaat gattttccaa aagaaagcat ataaatagat tctactatat ttgtctttcc
     7621 ttgaccattt ttaccaacaa gtagatttac tttcccatta aattccagat gcaacttttt
     7681 ataatttcta aaattaacaa gttgcaaact tttaagtttc acaaaaagtt ctcctttttt
     7741 tacaatactt ttattttagt tccttctatt ttaactatat ctcctgattt tatctttttt
     7801 cctcttctta attctatttc atcatttact gtcactaaac cttcttgaat taaaaatttt
     7861 gcatgacctc ctgttgatgc aatctctgct aatttaagaa attgatccaa ctttatatat
     7921 tctgattcta tagttatttc agtcataata gttcctcctt gtcactattt taaacaaatt
     7981 cctattgata cactaaaagt atattatacc ataaatatgc ttataaaagg agttgtctaa
     8041 gattagaaaa attttctaca aaagacaact ccttcatgtc tgctatatat ttgatgatat
     8101 tcttactgga agcagtaagt aaatataatt aacatcatct gttggtttaa ttatacaagg
     8161 atttacattt gtagtaaatt ctataaatat ttcctcatta tctatatttt tcaaaccttc
     8221 gataaaatat ctagaattga aagctatatc taggtaatct ccatctaaat ctatttcaac
     8281 ttcttcatac acatttcctt tttctgtgtt agaagtaatt gccattactt tatctcttat
     8341 agataacttt ataagattat ttttttctga ttgagacaat aaagacgctc tctctatact
     8401 atttaaaagt tccttagtgt ttaatttaac tctgctgtta tgttctcttg gcaataattt
     8461 tttataatca ataaaatctc cttcaagcaa tcttgtaata attttcgtat cattaattat
     8521 aaaaatagca tttttttcgt taaacccaac tttaacatta tcctctccag aaagcaaact
     8581 atttacatct ataagtgtct ttccaggaat tatgactttt atattttcag ttaaactatc
     8641 aactgaacaa ctttttacag ctaatctata tccatcaatt gctactaaat ttaagtttct
     8701 atctacaatt tctaaaagtt ctcccattaa aacaggtttt gtttggtcct gtgagatagc
     8761 aaatacagtt tgtttaatca tattttttag aatttcttga ggtatgctat ataaatcttc
     8821 ttcatttaat tctggtaatt taggaaattc ttttgctgca taacctttaa ttttaaatct
     8881 tgaatttaca caatttatgt aaatattatt ttctgaatca gtttctatct caacaaagga
     8941 atctggtaat tttctaatta tatctccaaa tagccttgca tctacaacaa catcaccttt
     9001 ttctatgatt tctgcttgta cataagtttc tattcctatt tcagcatcat atccagtaag
     9061 ttttaattga ccttcttctg tagatataag tatacctttt aataattcta ttgttgtttt
     9121 tccattaata gctttttgag caattccaat tctatttgct aggatttttt gattacaaat
     9181 tattttcaat gtggataacc tcctctggct ttttatatat aaaaataagt taaaatcata
     9241 gtagtaatag tagtaggtgt tgttgataat gttaataagt atgtataaca ttataaatac
     9301 aaagatatta acatgtgtat aagatgttaa tatctttgtt attttagact tgataatttg
     9361 ttaataattt ttgttcaaaa aaagtattaa caggttattc aagagatata aacatacaat
     9421 tgtgtataaa ttatcccttc aaatctgata taattttgtc tattttagtc ttaatttctt
     9481 cactttcttc tatatcctta gatactttgt catgagcatg aattactgtt gtatggtctc
     9541 tacccccaaa ctcttcacct attttaggaa gggataaatc agtaagctcg cgcgttaaat
     9601 acatagctat ctgtcttgga taagctattg aacgtgttct ttttttagaa ttaaaatctt
     9661 ccatctttaa attgaataca gaagatactt tttcttttat tctaagaaca tttatttctt
     9721 catttttaga agttgttata atatctttta aagcttctgt agcaagatca aaagatatta
     9781 ccctattgct aagagaagaa taagcaacca ctctagttaa tgcaccttct agttccctta
     9841 tgtttgactt aatatttttt gctatatatg acataacctc atttggcaca tctatacgtt
     9901 ctagttgagc cttttttcta agtatagcaa ttcttgtctc aaagtcaggt gcttgaatat
     9961 cagttataag tcccatttca aatctcgatc ttagcctatc ttctagtgta ggtatgtctt
    10021 ttggcggtct atcactagat ataattattt gtttgtttgc ttcatgaaga gtattgaatg
    10081 tatggaaaaa ctcttcttga gttctttctt ttcctgctat aaattgaata tcgtcgatta
    10141 gtaatacatc tacgtttcta tatttattcc taaattcttc gtttttatcg tcttttatag
    10201 agtttataag ttcattagta aatttttctg aagaaacgta aactactttt gagtcttttt
    10261 tttgactaac aatatgatga cctatagcat gcattaggtg agtcttacct aatccaactc
    10321 ctccatacaa aaaaagtggg ttataagctt tagctggaga ttctgcaact gcaacgcatg
    10381 cagcatgtgc aaatctattg ctattaccaa taacgaatgt atcaaatgtg tattttggat
    10441 ttagattggg gtaaagaact ctataattta aatctgtgct atcagaattt aaatcagcaa
    10501 cctctttttc gctcaataca aatttaatat tatatttttt taatgacagt tgactaatag
    10561 catcttcaat taaatgtaaa tatctattct ctaagatatc tttattaaaa tcactaggag
    10621 ccagtaagat taaatcatta agatgtattt ttaatggtac gatgttttta aaaaaggtat
    10681 taaaacttac tgaagttaag tcacctttta ttaattgtag ggttttgtcc cataaagaaa
    10741 ctatatccat aatataaacc tccgaacaga ataattaata ttttccacaa agttattaac
    10801 agaaaagcaa aaatatatat aaattttaca gaataactaa atttatggat aatggtgttg
    10861 ataaattaat aatagtataa attattaaaa aaatatgaaa agatataaac aatatgtaga
    10921 taaagttata aataacataa acatacaata aatggtgatt ataactagag tattgtcagt
    10981 aatcttaaaa gttatacaca aaagtatcca caagctgtga ataatttcta ataagttgat
    11041 aacatttatg cacattatca acaagtatat ttataatatc aaaatatatg tcaaacttca
    11101 atgatttgta actaatttat ccacaatatt aactaattgt tgataaaaat ataaacatgt
    11161 taaaattact ttatttgtgt atataattga aaaaaataat ttagaataaa attaaataga
    11221 tttttgctag tattttcaat aaaaaaaata cataatatat atatggtaga ttttgtgata
    11281 taagcgtccc aaaaactcgt tgacaacagt agtaaaagta tttataatta tatgtgttat
    11341 gtttactttg agggtaaagt tattattttt ataaacggaa aataaaatct gaaaggcggt
    11401 gcaaaataat gagtaaaaga acttatcaac caaaaaagag acaaagaagt aaagaacatg
    11461 gtttcagaaa aagaatgaag acgtctaacg gaagaaacgt gttaaagaga agaagagcta
    11521 aaggaagaaa tagattaact cattaattac aaaagggccg ctgcaaaggt ggcctttttg
    11581 tgtaaataat tacaattcat agctgtgttt atggaggtta actatggact ttaataggac
    11641 taaagggttg aaaaaagact ctgattttag aaaagtatat aaacacggca aatcttttgc
    11701 aaacaaatat ttagtaatat atatacttaa aaataaatca gattatagta gagtaggtat
    11761 ttctgtttca aaaaaagtag gaaaagctat tactaggaat agagtaagaa gattaataaa
    11821 agaagcctac agattaaata ttgatgaaaa aattaagcct ggatatgata tagtatttat
    11881 agcaagggta tctagtaagg atgctacttt taaagacata gacaagtcta taaaaaattt
    11941 agttaaaaga acggatattt ctatttaatt gtatgctata aatatggagg ttaatgactt
    12001 tgaataaaat aatttatata ttaaaggaaa taagtaggta tttatcgaat ttatgtattt
    12061 atttagtgag attttatcaa aagtatatat ctcccttaaa gggacctacc tgtagatttt
    12121 atccaacttg ctcacaatat tcaatagagg cgtttaaaaa atatggattt gtaaaaggta
    12181 tgtatttaac gataagaaga cttttaaaat gtcatccttt tcatccagga ggttacgacc
    12241 ctctaaaata aaagagagta actattagga ggtataaaaa aattgaatat aataggaaat
    12301 ttcttaggat tgattcttaa ggtaatattt gaatttgtta atcattatgg tatttctata
    12361 atacttttta cgatacttgt aaagattatt ttattaccat taacaattaa gcagactaag
    12421 tcaacaaagg caatgcaaga tatacaacct cgtataaaag agatacaaga aaaatataaa
    12481 aataagccag aaaaacaaaa tgaagaaatt gttaagttat atggagaagc taaaattaat
    12541 ccactatctg gttgtttacc tttattaata cagtttccta tattaatagg attatttagc
    12601 gttttgagag aaccagttgc tcatggcgtt tttgcaaaca aagctgcatt tttagcagct
    12661 gacaatgggt ttttatggat aaaaagctta acatcaccag attatgtatt agcagtattt
    12721 tcaggagcaa gtgcatatgt catgcaaaaa gtaatgacac ccaaagatca gttacaaggc
    12781 tctatgaaag taatgacata tgtaatggca ggtatgtctt tctattgggg atttatattc
    12841 ccagcaggac ttacattgta ctggacagta agtaacttat tctcaatagc tcaatattac
    12901 ttaataatga atcctttaaa agctaaactg gctgctaact ctaaggagga aaaagttaat
    12961 gagaaaaagc ctaaaattaa taaaaagtaa gagtaaagag gaagctataa gtaaagctat
    13021 agcagagttg aatttaaaag cagaggatat agaagtagaa atacttgaaa atccaagtaa
    13081 agggttttta ggttttatag gtgctaaaga tggtacttat gaaatttttg ttatcgagag
    13141 ggaagtagat gtagctaaaa attttataga ggtaatgttg aaaaatgcaa atgttgatgc
    13201 caaagtcaat gtatctcaaa aagataattt aatcatggtt gatattgaag gcaaagaagc
    13261 tgcaagttta attggtagaa gaggggaaac tttagattct attcaatttt tgactggatt
    13321 agctcttaat aaaataaata aagattctca tacaagagta cttgtagata tagaaaatta
    13381 tagatcaaaa cgagaagaat ctttaataag atatgctaat aaagttgcta gagaagtagc
    13441 gaaaacaaga aaaactaaaa aattagatta tatgaatcca tatgagagaa gaataataca
    13501 ttcagctctt caaaatgaca aatatgtaat tacatatagt gaaggaaccg atccatatag
    13561 aagattagta attgagtgta aaagataaag tcaacctcct aaacattagg gggttttatt
    13621 ttttaatatt attaaatcat taatgattgg ttaaatgtaa acctatatgt aaaaaattat
    13681 gaattaagag gtgataaatt tgtttataga tgatacaatt gcagcaatag ctacagcacc
    13741 tggagaaggt ggtataggta tacttagaat aagtggagaa agagctttga aggttgcaga
    13801 agaaatcttt aaatctatgt cgggaaagag tattgaagaa tacaataaga gaacattaat
    13861 atatggaaat atattggata atgaaaatat aattgatgaa gttttattgg catatatgaa
    13921 aggaccaaac tcctatacag gagaagatgt tatagaaatt aattgtcatg gtggatttat
    13981 ttcggtaaag aagatattag aattaatact atcaaaagat gttagattag cagaggctgg
    14041 tgagtttact aaaagagcat tcttaaatgg aagaatagat ttatctcaag cagaggctgt
    14101 aattgatgtt ataaaagcca aaactgatat agctcatgaa gttgctcaaa atcaattaga
    14161 gggttcttta tcaaagaaga taagagaatt gagagataaa gtcactgaga tattagctca
    14221 tgtagaagtt gctatagatt atcctgagga agatattgag catataacat atcaaactct
    14281 taaagaaaaa actgatgaac ttaaaaaaga gattaaaaaa ttatatgata cagctgaaag
    14341 tggaaaaata cttagagaag gcttaaagac ggtaattgtt gggaaaccaa atgtaggtaa
    14401 atcttcacta cttaattcta ttttaggaga gaatagagca atagttactg atataccagg
    14461 aactactaga gatgttatag aagagtttgt aaacataaaa ggtatacctt taaaaattgt
    14521 tgacacagca ggtataaggg atactgatga tatcgttgaa aaaataggtg ttgaaaagtc
    14581 taaagaatca tttactagtg cagatttgat agtaatggtt ttagatgcat ctagaaagtt
    14641 gtcagaggaa gatatagaga tattagaaaa acttaaggat aaacaaacaa tagtgctgtt
    14701 aaataagaat gatttgaaac aagagattga agaagaaaaa atacttaaat atgtagaaaa
    14761 taatagtata ataaaaatat cagctttaca acaagaagga atagaagaat tgcaagataa
    14821 aatagagtct atggtatata aaggtagtat caaaaataat tctagtttag tagtaacaaa
    14881 ttcaagacat aaagatgcac ttagtaaagc atataaatct gcaacagatg ctttaattgc
    14941 tttggaacaa agtatgccat ttgactttgt agaagtcgat ttaaaaaata tatgggacta
    15001 tcttggatat attaatggtg atacagtaac agaggattta ctagataata tattccataa
    15061 tttctgtatt ggtaagtaat gtacaaaagt aaatttgttt ttattataga gatttttaaa
    15121 aaatttgaag tgtttctcat gaaacattaa ttttgaaaag aaaggaatta taaatgataa
    15181 agtttgaagc aggaaaatat gatgttatag tagtcggagc aggacatgct ggatgtgaag
    15241 ctgctttggc tactgcaaga atgggatata aaactttgat aataacaatg tctttggatt
    15301 ccatagcatt aatgccttgt aatccatcaa ttggagggac tggtaaaggt caattagtta
    15361 aagaaataga tgccttaggt ggtcagatgg gattaaatat agacaagaca tatatacaaa
    15421 gtagaatgtt aaatactgcc aaaggtccag cggtacactc tttaagagca caagcagata
    15481 aatttaaata tcatgaagaa atgaaaaaga cattagaaga tgaaccaaat cttgatatag
    15541 ctatggatga agttgtagaa atacttcatg aaggaaatgt tgtaatagga gttggaacta
    15601 aactaggatg ttcatttaaa tctaaagctg taatattggc cactggagtt tatctgaact
    15661 caaagatata tatgggtgaa gttgcatttt atgaaggtcc taatgcattg gggtatgcaa
    15721 aatatcttac agatagctta gttgagcttg gtcttagaat gagaagattt aagacgggaa
    15781 ctccagcaag agttcataga gatagtatag acttctctgt aatgtcttta caagagggcg
    15841 atgaaaaagt aactccattc tcatttatga atgaaaatat agaaaaaaaa caagaacctt
    15901 gttatttaac aagaactaca gaagaaactc aaaaagttat actggataat ttaaaaaggt
    15961 ctgctatgta tagtggagta atagaaagta ctggtccaag atactgtcct tctatagaag
    16021 ataaagtagt aagatttagt gataaaacct cacatcaatt atttatagaa ccagaagggt
    16081 taaatactaa agaaatgtat atacaaggaa tttcaactag tttacctttt gaagttcaat
    16141 tagatatgta caaaactata aagggacttg aaaattgtaa gataatgaga cctgcatatg
    16201 ctattgaata tgattgtgtt gacccaactc aactaaaaat aagtttggaa ataaagggtg
    16261 tcgagaactt atttagtgca gggcaattta atggaacttc tggatatgag gaagcagcag
    16321 ctcaagggct tatggctggt ataaatgcag ttagaaagat agaaggaaaa gagccgtttg
    16381 tattagaccg ttcagaagct tatataggtg tcttattaga tgaccttgtt actaaaggaa
    16441 ctaacgagcc ttacagaatg atgacatcaa gagcagaata tcgactatat ttaagacaag
    16501 ataatgcaga tatgagatta actcaaaaag gttatgatat aggattagtt aaaaaagata
    16561 gatatgaaag gttcctaaat aaaaaggctg ctgtagataa agaatttgaa agattaaaaa
    16621 atgaaagagt tacaccaaaa gaagtaaata gtttgttaga agaaaaagga gcaacaccaa
    16681 taaaggttgg aatatctcta tatgaatttt taaagagacc agaggttact tacgaattgc
    16741 ttgaagaatt agggaagggc gctggagaag atgtttcaag agaagttaaa gaacagtgtg
    16801 taataataac taaatatgaa ggttatatag agaaacaatt gaaacaaata gaccaattta
    16861 aaaaacttga gaataaaaag ctggatgaga aaataaatta ttcatctata gaaggtctta
    16921 gattagaggc tagacagaaa ttagatgata taaaacctat ttcaataggg caagcatctc
    16981 gtatatcggg tgtttctcca gctgatatat cagttttact tatataccta gaacaagtca
    17041 gaagaactag aggtggcaaa ggtgaataat atagaacttc tgaaaaacgg gattgaaggt
    17101 tttaatatag atacgaatga cagtatgtta gaaaaattta aaatctatag agagatatta
    17161 gttgaatgga ataaaaagat gaatcttact ggaatagaag atgaaaaaga agtgtatata
    17221 aaacattttt tagactctat ttcagctgta aagaatggat atataaaaaa tgggatgtct
    17281 ataatagatg ttggtacagg tgctggtttt cctggaatac cattgaaaat atgtttagat
    17341 agcttagaac ttactttgtt agattcgtta aataaaagaa taaacttttt agaggaagtt
    17401 agtagagtac tagagttaga taatattaca tttatacatg gaagagctga agattttggt
    17461 aaaaatgaag actatagaga aaaatatgat gttgctacgg caagagctgt tgctggatta
    17521 ccgattctta tggaattttg tgtaccattt gtaaaagttg gagggtattt tatttgctta
    17581 aaaggtccga atgctaattt agagctagaa gaatcacaaa aggctattga tgttttagga
    17641 ttggagtata ttgaaaaaat agatgtagag ttaccagagg tagatttaaa tcataatata
    17701 ttagttttta aaaaggtgat ggaaacacca gttaagtacc ctagaaaagc tggtagacca
    17761 gctaaaaatc ctattaagta atgaaaaaag taatgaaaaa attattattg gtaagcttaa
    17821 ttatttctta ggaaataatt aagcttaccg taaaaaaaca aaaataaagg aattattaaa
    17881 gtagatgcag aaataaattt gtatgtacat atagagaaca aaaataattt atatctaaaa
    17941 taagagaggt atgttatgga agataaaaga gttatggaga tacctataga agatgtagtt
    18001 ccaaatccat atcaaccaag aaaaatattt tcacaagttt cattggagga attgagcaat
    18061 tctataaagg tatatggtat aattcaacct ataacagtta gagcaaaaga tggcaaatat
    18121 gaactaattg caggagaaag aagattaaga gcagctaaat tagcagagct taaaaccata
    18181 ccagcaatta taaataatat gaatgatgaa tcttctgctg ttctagcgtt attagaaaat
    18241 ttgcaacgag aagacttaaa tttcattgaa gaagcaattg gttatgaaaa cttaataaaa
    18301 gaacatgctt ttactcaaca gcaattagca gaaaaattgg gcaaaaatca atctactgta
    18361 gcaaataagc ttagaatatt aaagcttcca aacgatataa aaatgaagct aatagagaat
    18421 aatttaacag aaagacatgc tagagcattt cttaaactac caagtgaaga tttaatgcaa
    18481 agtgtgttag acaaagtcat aaaaaatgaa ttgactgtta aaaaaacaga aaaattgata
    18541 caagatgtat tagaagaaac taaagttcaa gaagagcctg ataaaaaaca gaatataaag
    18601 ggtgctatga gtataagaat ttacataaat actataaagc aggcctttga tgctatatca
    18661 aatacaggaa ttgatgctaa gtataatgaa atagataagg gagattatat ggaagttgtt
    18721 gtgaaaatcc ctaaaaaata gagattactg cttaccagta atcttttttt gtaatataag
    18781 ccttgtaata taaattgatt tatagacatt atttatactt aaaaaacacc tattcaacat
    18841 ttaaaattaa tttaattctt aaagggggga acatcatggg caaagttata gctgtattca
    18901 atcaaaaggg tggagtcggg aaaactacaa caaatgtaaa tttaagtgct agcttaggaa
    18961 ctttgggaaa gaaaatatta gtattagatt tagacccaca aggaaataca actagtggat
    19021 atggtattaa taaaaacgaa gtagaaaata caatctatga aattatgtta gatgggttac
    19081 atattaaaga agcaataata agtactgaat ttgagaatgt agatgtagtt ccatcagcta
    19141 ctgaactatc aggtgcagag atagagctta catctaaaac taatagagag tatattttaa
    19201 aaaattccat aaaagcggta atagatgaat atgattatat atttttagat tgtccaccct
    19261 cactggggat gcttacaata aattgtttaa ctgctgtaga tagtgtttta attccaatac
    19321 aatgtgaata ttatgcttta gaaggtgtta gtcaattaat ggagactata aaattagtaa
    19381 aatcaagatt aaatgctgat atagaaattc aaggtgttgt tttaagtatg tttgatggaa
    19441 gagctaattt atcaatacaa gtagttgaag aagttaagaa atactttaaa ggtagtgtat
    19501 atacaacttt aattccaaga aatgtaagac ttgcagaagc tccaagtcat ggaaaacctg
    19561 taatttatta tgataaaaga tgtagagggt ctgtagctta tttggagcta gcagaagaat
    19621 ttatagattt agaagaggag gaatggtagt atggagaata agtctaaaag aagtaataga
    19681 ttaggtagag gtcttagtgc attgatacca gaaattaaag gagaaacttc agaaaaagaa
    19741 atagtcaaca tagatataga caaaatatat ccaaacgaag ttcaacctag aaagcaattt
    19801 gatgaagaaa agataaaagt attgtcggac tctataaaaa attatggtgt tttacagcca
    19861 atagtggtta aaatggatga aaataataaa tatatgataa tagctggaga aagaagattt
    19921 agagcatcaa aacttgcaaa taaaaatcaa atacctgcta taattaaaga tatagatatg
    19981 aaagatataa tggagatagc cttaattgaa aacttacaga gggaagattt aaattcaata
    20041 gaagaggctc tagcatataa gagtttaata gagcattaca atgtaactca ggaagaaata
    20101 tcagaagctg ttgggaagag tagacctcat ataactaata cactaagact tttaaatctt
    20161 ggacaagatg ttatagaaat gatagacagt ggtagaatta cagcaggcca tggtaaggct
    20221 ttattgagaa ttgcagataa agatttgcaa cttcaaatag cgaaaaagat agaagaagaa
    20281 gaactttctg taagagaagt cgaaaatata gctaaaaaaa tatctgaaaa taaacaagaa
    20341 gaacctaaaa aatctaaacc taaggatgta tttattttag atgttgaaga taaacttaga
    20401 aatatatttg gaacaaaggt gaatatttct aaaggaaaga agaaaggtaa aatagagata
    20461 gaatactata atgatgatga tttaaatagt attgtatcaa tgcttcttga atagaacaaa
    20521 aatataaaac agagaggaag attgttatga tttatttaga taatgctgca actacatatc
    20581 caaaaccaga aagagtgtat aatgctgttt tagattgtat gaaaaattat tgtgcaaatc
    20641 caggtagagc aggccataaa cttgctatga gagctgctag ggagatatat gatacaagag
    20701 agaatatagc taagttgttc aatgtaagta atcctatgaa tatagtattt acatctaatg
    20761 caacagattc tttaaattta gcgataaaag gtgtattaca agaaggagac catgtaataa
    20821 caacgtctat ggagcataat tcagtaataa gacctataaa agcattggaa aaaaggggta
    20881 ttgaaaatac tgtagtaaaa tgcgattatg agggattttt agattatgaa gatttagaaa
    20941 aatcaataaa gagtaatact aaactgattg taacaacaca cgcatctaat gtatgtggaa
    21001 ctttaataga tataaaaaaa gttggagaaa tagctaaaaa acataatata ctatttttag
    21061 tagatgcatc acaaacagca ggtgtttatg atatagacgt aaatgaatgt aatatagata
    21121 tgttggcaat gccaggtcat aaatgcttat ttgggcctca aggaacaggt atattatatg
    21181 taagagaagg gttgaactta aatatattaa aagaaggtgg aacaggtagt aaatcagaag
    21241 aaatagttca accagagtta ttcccagata agtatgaatc aggaactcat aatactccag
    21301 gtatagcagg tcttaaccaa ggtatactat ttatatttga aagaggaatc aacaatataa
    21361 gacaacatga agaagaatta tgtcaatata tgatagacaa actagaggaa gtatcagata
    21421 taaagatata tggaccaaag gatagtaaaa aaagagcatc agtaatcgct ctaaatatag
    21481 gagatatgga ttctggagag gttactttct tattagatag tgattataat atagcaacta
    21541 gatcaggaat acattgttca ccactagcac ataccacttt aggtacttta aaacaaggtg
    21601 cagtaaggtt cagtatagga tatttcaaca caaaagatga gatagataaa gcagtggaag
    21661 ctttgaaaaa aatttcaaaa aataaatagc atgagattta ataatataga aataaaaaaa
    21721 ggggatattt caaaataaaa atttgaatca tctccttttt tgtacaaaaa agaaaagggg
    21781 ctcctaagaa cctctaatct atttgataat tgtttcaaga aattacttta agtaatctcc
    21841 ttcttcaaga actatatgac cactttcgta attagaacca tcaacagtaa tttttatttg
    21901 ttcaacattc atatttttta tgtaagtacg agcaactgaa tcaagcatta aagtttctgc
    21961 atcactacct aagtttgact ttgtaaagtc agagctaaca tctaatatac cagtttttac
    22021 accatcaatg tcttttgtag taaatgaatt taattttgca gattctggaa caactttaag
    22081 tttttgaagt tcttcaaata aagtgttctc atcaatttta tttaaatcaa ctttattttc
    22141 aattaaatct gtcttatcta catcaaaaga gtaaatagta gctgattgag ttttagtttc
    22201 ttcttttgga gtaggtttag ctttgttatt aggaacctct ttttcagtat tgttttcttc
    22261 ttttggttgt tcaacatttg tattgctctt agtttctttt ttagatgtat cacttccatt
    22321 ttgagcatta gtacaaccaa ctgcgaatat agatatagat aatatactta acactaacat
    22381 tattttctta tttttcataa aaatttctcc tctcttaaaa actattctta tatataatta
    22441 tagtcgttat gagcaaatat atgaatacaa aatagtaaca aatttaaaaa atgatttatt
    22501 taaattaata aaactcaaaa taaactaaat tttagtcatt tttatgggaa atcatttaat
    22561 gtacagtgaa aatattgtaa aataaaagta gtgtttttaa aataaatata agttataatt
    22621 atattataaa aaaatgtctt caaaaggtgg gaatagtatg gaaattttga gcttaggaga
    22681 aaagattaaa aaattaagaa aagaaaaaaa catgacatta aaagaattag ctggagatag
    22741 gataacagca gcacaaataa gccatataga gagggataaa tctcatacta gttatgaact
    22801 gttggaatat ctaggcgata agctagatgt aagtgtagaa tacttattag agaccaagga
    22861 aatgcaatca aaaaagataa ctgataattt aatactacag agcgaaattt atataaaaga
    22921 aaatgaatta aacaaggctg aggatcaaat aaaagaagtt ttagatatat gtaagagata
    22981 cgatttaatg gagaactatg gcagatgtaa ttttttaatg gctaatatta atttgaaaaa
    23041 atctaattat aatgatgcta tagaaaactt tgaaaaggca ttgtacttct ttataaaaaa
    23101 tagtgatagt gaaaatatac ttaagtgtta tttaaacata gggaaaatat atatgcagga
    23161 agacttttat aaaggtgcta taagccactt taattttgca gaggaaattt tgtcagagaa
    23221 taaatttgag gatgttaaca tacacaagga actatatagt aagatggcat attgttacat
    23281 aaaactagat aatccaaata tgtcattgaa gtacatagaa aagataaatg aaatagataa
    23341 tagaaatgat agaaaagaag atgtcgatat tttggtgtta aaagcaaata atatgcttga
    23401 gattggaaaa tatgaagaat caagagatta ctttaaaaaa gcactaaaaa tacttgagag
    23461 tgaggataat aaaactggat tagcaaatgt gtatttaaca atttgtgatg tttacagaaa
    23521 aataggtgaa acagatagag tacttgaata ttcacaaaag gtatatgaca taaagaaaaa
    23581 tgatgaagat gaatacatga tgtcaggatt atttaagata atagaagcat atatagataa
    23641 agaagattat gatttagcta gaaaatattg taagatagcc ttagcttcat caataaaaaa
    23701 taaaaataaa ttcaatgaat ataaagcatt gagattctat gctaatatgt ataaaaatca
    23761 gaatgaagta actcttgcaa ttgaatatct gattaaatgc ataaaaatag tatcagattt
    23821 aggcaacaat agaatattgg ccaatttata tatagactta ggtcaattat attcaaatat
    23881 atcaaaagaa aaagagttag aatattatca aaaaggtgta tttatgtaca aaaatttaga
    23941 aataatgtag ggtaaataaa cctataaggg tatagaaaca atctataaca agcaagataa
    24001 tatctatgat aaaatataaa ttgtatgaat atttttaagg agatgaatca gacaatgagt
    24061 ataaaaatag atgcgagagg gcttgcttgt cctaaaccag ttataaatac aaaaagagaa
    24121 ttggataacc tagaagaagg tgttgtagtt acaatagttg ataatgaaac agctaaggag
    24181 aatatattaa aacttgctaa atctttaagt tgtgaagcaa atattgttga cgaaaaagag
    24241 aattttatat ctatagaaat tagaaaaggt aaaaatatac tagataaaca aaatgttgta
    24301 gataataaag aaagtgaatt agacaataca tgtatattta tatcttcaga taagatggga
    24361 cttggaaatg acgaattagg aaaagtgtta ataaaaggat ttatatatac attaacagaa
    24421 tctaaacctt atcctaagta tgtactttta gttaatggag gagtaaaatt aagtgctgaa
    24481 aatgaagaaa ccatagaaaa tctaaaaata cttgagaata tgggtgtaga agttttatct
    24541 tgtggtactt gtttagatta ttataattta aaagacaaat tacaagtagg tacagttaca
    24601 aatatgtata ctatagttga gacattaaag aatgcatcaa ataccatttc tatataatgt
    24661 atgtttgttt aataatataa aactaataat aaagattaac tcaaatagat agtcagaaag
    24721 gattaagtaa tgaatcaaat gtatatagtg tcatttaatt cgacacatca tgcgataaga
    24781 tcagaaaagt tatttggtga aaatagtcta aaagtaatgg ctcttccaac accaagagaa
    24841 ataacagcaa gttgtggaat atcaattaaa ttttcttttg aagatatgga aaagataaaa
    24901 actattttgg ttgaaaataa tgtagatata aaaggaattt attgtataag taaattagaa
    24961 aatggttcaa aagaagtaga gaagttagat taggaggcta attatttatg ccaatggatt
    25021 taaaaatagg tgatattgtt gaattaaaaa agcaacatgc atgtgggtgt aaagagtttg
    25081 aaatcataag aacgggaatg gatataaaga taaaatgtac taaatgttca aggctaataa
    25141 tgcttgatag agagacctta gaaaagagag taaaaaagct aataaaaaag tgataaaaat
    25201 ttaacactta aaaaatgtca aataccgtat attaatatcc aaaattttgg tataataaga
    25261 attgaagaaa acattttcat gggggtgctt taattatggc agttaaatat gcaaaaagaa
    25321 tgcaaggatt acaaggatca gaaatacgtg agcttttaaa acttactcaa caaccacaaa
    25381 taatatcttt tgctggtgga atgccggctc cagagttatt tccagttgag gaaatgaaaa
    25441 aagtatcagt tgcagtgctt gaagaaaatg gaagatcagc tatgcaatat actacaacag
    25501 aaggatatga accattaaga gaaaaaatag cagctagaat gaatgataaa aacaaaacta
    25561 atgtaaacaa agatgatata ttagttacaa gtggttctca acaaggtcta gattttgcag
    25621 gaaaagtatt tattgatgag ggtgatgtaa ttttatgtga aagtccatct tacataggag
    25681 ctataaacgc atttaaatct tatcaaccta aattcataga tgttccaaca gattctgatg
    25741 gaatgataat ggaagaatta gaaaagatac tagaaacaac tgatagaata aaaatgattt
    25801 acgtaatacc tgacttccaa aatccaacag gaagaacttg gccacttgaa agacgtaaaa
    25861 aattcatgga aatagtaaat aaatttgaaa taccagtaat agaagataat ccatatggag
    25921 atttaagatt tgaaggagag actttaccat ctttaaaatc aatggataca aaaggattag
    25981 taatattctt aggaactttc tctaaaatat tctgcccagg atacagatta ggatggactt
    26041 gtgcttctcc agaaatttta tctaaattta actttgcaaa acaaggtgca gacttacaag
    26101 catcaactat atctcaaatg gaagtaagca aatttatgga tatgtatgac ctagatgcac
    26161 atgttgacaa aataaaagca gtttatgtta aacgtagaga tgtaatgctt aagactatgg
    26221 aagaagagtt cccagaagga ttagtattta ctcatccaga aggtggatta tttacatggg
    26281 tagagcttcc aagtaattta aatgctaaag aattaatgcc aaaatgttta gagaagaatg
    26341 ttgcttatgt tgctggagga ggattcttcc ctaatggtgg tagagaaaat actttcagac
    26401 ttaactattc aaatatgcca gaagaaaaaa taatagaagg tataaaaaat atagcagctg
    26461 tattaaaaga agctatgggt gtagaagctt aattaaaaat aataacttat atataataca
    26521 agggatggtt gttgccatcc cttgtttgtt tgaaaagtat ataattcacc ttatactaaa
    26581 ctttgtccaa aatttaaatt gacagaaata agaataaatg ataaaatgtg taggtatgag
    26641 attttagtct catttctctg ctctaagagt gtagagccgt taagtccaaa gggaggtgaa
    26701 ttatagtgag aaattatgaa ttagtttatg tggtaaagcc aaattctgat gaagaagtaa
    26761 gagaggctat actaaacaaa gttaaggaag ttgttgcaac tgacggagaa atagttaaag
    26821 ttgatacttg gggaactaaa aaattagctt atccaatagc taagtttaca gaaggtttct
    26881 atgtattagt taacttcaaa tcagcagtag acgttcctaa agagatagac agaaacttaa
    26941 agataaatga aaacgtaata agacacatga tagttgttgc ttaataactg gttttattat
    27001 aaaaaatagg tggtgttttt atgaatcaag ttgtattagt gggaaggttg actagagacc
    27061 ctgaattaag atacatccca ggtacaggaa caccagtggc atcctttaca atagccattg
    27121 atagagacta tgtaaaaaaa gatggatcta aagaaactga ttttatacct gttgaagtaa
    27181 tggggaaatc tgctgaattt tgtgctaact acataactaa aggtagatta gtagcacttc
    27241 aaggatctat aagagtagac aattatcaga cacaatcagg tgaaaagaga acttttacaa
    27301 aagtaagtac tagatcagta caagctttgg atagtaaaaa taaatcggaa aattcatata
    27361 gagagagtgc tccagctttt gagccaagct ttgaacctca aggtttagac ccacaaggtt
    27421 ttcaagctat agatgatgac gatataccat tttaaaaagg agggaaaaaa gtcatgatga
    27481 ataagaaaag acgtaagaaa aaaagagttt gtcaattttg tgctgacaaa aacgctaaaa
    27541 tagattacaa aagtactcaa agattacaaa agtatataac tgaaagagga aagatattac
    27601 caagaagaat atctggaact tgtgctaagc atcaaagaga attaacagtt gctataaaaa
    27661 gagcgagaaa tatagcactt ttaccatata cattagacta aaaaaatgag ccttgtgctc
    27721 attttttatt atatgtattt atatatctaa atgaggcgag ctataaagct cgtttttttg
    27781 tttatatact taaatatatt attatttatg atataatatt atatattaag gagggttgta
    27841 aacgtgaaaa tagataaagg ttctgagata acgagaaaca taaagataat agaatggatg
    27901 aaaacagaaa tattaatgag tgtaagtgat ttgtttaatt tattgtttaa aggggtaaaa
    27961 ccattagatg aagcaattca agatacttta gcaaatataa taatgataac atatctctta
    28021 gcaaagagat taggaattag ttttagagat gtggattata aagtcaagga aaaaataaaa
    28081 attggtatag atgaggacca tagcgttgaa agatggtatg gagatttatc taatttaaaa
    28141 aaacatatgg ataataggga gtgatattaa attgaataat aaaattagac tatctaaggc
    28201 aatgtctata atagttttag ctataataat cgctttagta atagcctata ttccaatgct
    28261 aggaatattt agtatgttag cagctgttcc atatgtaatt ataggtgcta ttactgatag
    28321 aaagtattct cttatatcta ttttggttac attttgtgta ctgattctat ttgcagacat
    28381 ttcttatgca ttaaatatat gtataatgta ttctttacca ggtatagtaa taggaaagat
    28441 gctaaagaga agctttgaac aagaggacag taataaattc gaaccgatat atggtggaac
    28501 cataatattt gtactttcaa tgcttgtata tttttttgta ttaaagacat ttttaaatgt
    28561 gaatctatta gatgaagttt ctaagatgat atcagaaatt gtaaatattc aaaaaaatag
    28621 tttttctgca actgaactta aagtgtttga taaaatgaag ccagatgaga ttgtaagtta
    28681 ttttacaaat atgctaccaa tgatgttatt tttacaaggg ttgttatcag cgtttgtcac
    28741 atattatttg agtgtatttt ttataaaaag gattacaaag atgaatataa gatttcctaa
    28801 atttgctgat ttttatttac caggaaatgc tatactcaca actttcttac tttatttatt
    28861 agtcttattt attcaaatta ttggttcaaa attatataca gaattaataa tgactaattt
    28921 acagctagtt tttaatttaa tgtttgtaat tcaaggtata gcagtttgca tttatttctt
    28981 aaagaaatgg ataagacagg gaccaaataa aattatgttt ttttcaggga taattttatg
    29041 tttatttgga tttatgggaa tatcttttgt tggtatggta gatagtataa ttgactttag
    29101 aaaggtaaga agctataaat ccacttagga ggatagaaat gagtaacaaa caaaccttta
    29161 aattaaatat gccagaaata aatttatata taattgttat tggtatttct agtataattt
    29221 tgctttatta caacttgtat gtagggtgtt tatttttctg tatttttgta tatatggttt
    29281 ttcacaattg gagaactact aatattagac gtcatgaatg gacagagtat attcaaaatt
    29341 tatctttaga tatagatgaa acaactaaaa aagccataat aaatcttcca ataccattat
    29401 gtattttaga atttgatgga aatatatcct ggtataatgg aaagttttat gatatgattg
    29461 gtcaaaaaga tttacttgat aaaaatatag aggatatagt taaaaatctt aatttaagaa
    29521 aagtattaaa tgaaaataaa gagatgtaca cagaaataaa ctataaagaa aaagaatata
    29581 caataattta taatgttata aaaaatgatc aagaaaaaaa tcctaaatat ttgatgatat
    29641 tatactggat agacaagact gaatatttaa aagtaaaaca aaattatgat gatgaaaaaa
    29701 atgcaatgat gctaatacaa gtagatggat atgatgaagt attaaaaagt gcagcagaag
    29761 ataagagagc tttaattaat gttgaagtag agaaaatact ttctgcttta gaattaaatt
    29821 caaatggtgc attgagaaga acttcaaaag acaaattctt cttggtaatg cataaaaaag
    29881 agctaaaaaa attggaagct gagaagtttt ctattttaga tacaataaga catattgatt
    29941 atggaaataa tcttcctgtt actataagta taggaattgg tatagatgga gatacattaa
    30001 atgagaacct aaaacttgct acgggtgctc tcgatttagc acttggtaga ggtggtgatc
    30061 aggctgttgt aaaaacaaaa gataaatttg tgttttatgg aggaaaatct aaagctgtag
    30121 aaaagaaaac caaagtaaaa tccagattaa taggtcatgc tttaagagag gttatacaac
    30181 aaagtgacca agtttatata atggggcata aatatcctga tatggatgct atgggagcag
    30241 cagttggtgt ttatgatata tgtaaatcct gtaacaaaac tgcaaacata gttttacaat
    30301 ctgtaaatga atctatagaa atatttataa ataaaataaa tgaaaataat tactataaaa
    30361 agctgtttat tggaaaagag gaagctattg acaactgtac taaaaataca ttagttgtag
    30421 tagttgatac tcatagacca aattatactg aatgtgaaga actgttaaag ctatcagaga
    30481 aggtagtagt tatagaccat catagaagag gtgtggagtt tataaatgat gcagtgcttt
    30541 tattccatga gatatatgta tcctcaacgt gtgaaatggt tacagagtta gttcagtata
    30601 tggatgaaga tgtaacaata aataaactta cagctgaagg gcttttagca ggtataagtc
    30661 tagatactaa aaactttgca ttcaaaacag gtgttaggac ttttgaagct gcttcttacc
    30721 ttagaaaagt tggagcagat actatagagg taaagaaatt cttcaattct gatgtaaaag
    30781 atttcataat aaaagctgaa ataattcaaa gtactaaaat aattaataat agaatatgtt
    30841 tagcatattc aagtactgag atagatagta taaatgttat aatagctcaa actgctgatg
    30901 agttattaaa tatcaaagaa gtagaagctt cctttgtatt aggtgaaaaa gatgatacta
    30961 tatttataag tgcgaggtct ttagggcaaa taaatgtaca tgtacttatg gaaaaattag
    31021 gaggcggggg acacatagat atagctggag cacagttaaa aaatgtttct ctaaaagaag
    31081 cttataagat ggtaaataaa ataatagagg agtatttgga ggaggaagaa tagatgaaag
    31141 ttatattatt aaaagacgta aaaggaactg gtaaaaaggg agaaatgaaa gaagtaagtg
    31201 atggatatgc aagaaatttc ttatttccta aaaagatggc tgtgcaagca gatagtgtag
    31261 caataaaaga attaaatgaa aagaataaat ctaaagaaat aaaagcacaa aaagagtatg
    31321 aagaagcagt tttattaggt aagcaaatgg aagaaattaa tatagaaata tattcaaaag
    31381 caggagaagg tggaagatta tttggttcaa taacttctaa agaaattgct gagcaattaa
    31441 agaaacaaaa agacatagac gtagataaaa gaaaaatatt attagatgaa ccaataagat
    31501 ctttaggttc aactttcgta gaaataaaaa tacatcaaaa agtaactact aaaataagag
    31561 tggatgtaaa agaaaaacag taataactag aggtgattaa gatggaagat atgacgagaa
    31621 ttcctcctca tagtgtagaa tcagaacaat caatattggg ttctatactt ctagataaag
    31681 atgctataat aacggttaca gaaactataa agcctgatga tttctataaa gaggctcaca
    31741 aaataatata tgaatgtatg ataactttaa gtaataaagg tgagcctata gacttgataa
    31801 cattaacaga agaactaaga aaacaagggc atcttaatga tattggagga atcagttata
    31861 ttacaagtct ttctactata gtaccgacga cttcaaatgt aaaatactat gctgatatag
    31921 taaaagaaaa gtctgtactt agaaagctta taaaagcttc taatgaaata ataaatctag
    31981 gatatagtgg agcaactaag attgaagatg ttttagaaca agctgaaaag agtatatttg
    32041 atatatcaca ggagaaaact agtgatgatt ttaaatctat aaacttagtt ttgatggatg
    32101 cctatgatat gatagaaaaa ttatatacta acaagagtga tgtcactggt ataactactg
    32161 gttttaaaga tttaaacaaa aaaataaatg gtcttcaaag gactgattta atattaattg
    32221 cagctagacc agcaatgggt aaaactgcct tttctttaaa cttggttcaa aatgcagcct
    32281 taaaaggtga tgcctctgta gctgtattta gcttagagat gtctaaggaa caattagtac
    32341 aacgtatgtt atcttcacaa tctagtgtag aattaaaaaa aataaagact ggaacactta
    32401 atgataatga ttggcctaga attatagatg ctatggcagt attatcagat gccaaaatac
    32461 acatagatga tactcctggt ataaaaatat cagaactaag gtcaaagtgt agaaagttaa
    32521 aaatagaaaa aggactagat ttagtgctta ttgattatct tcaacttatg gaaggtgaag
    32581 gtaataatga aagcagacaa caagagatat ctaagatatc aaggtcacta aaaatattag
    32641 caaaagaatt aaactgtcct gtagttgcac tatctcagtt atcacgtgca ccagaacaaa
    32701 gagcagacca tagacctatg ttatctgatt taagagagtc tggagcaata gaacaggatg
    32761 cagatatagt tatgttctta tacagggacg aatattatca tgctgattct gagagtaaaa
    32821 atataggaga agtaataata gcaaaaaata gacacggtga aactggttct gtggaacttg
    32881 tttggcttgg tgaagttcaa agatttgggg ataagttgag agacctataa tctaacgaat
    32941 atccacagaa cgtcctttct ttctacagga aaaatgtgga tacatgtcac taaatatgtc
    33001 caaacattga aatttagcta aaaaactatc cacactatcc acagatagcc tgttgataag
    33061 tgtgaataag tagataaagc aagcttttgg cttgctttat ctgtgtataa atattaatta
    33121 ttaggaggaa taatatggaa aaaataagct taaaatatat atatcccaat ataattaaag
    33181 tacttgatga aataaactta tttagagtaa ttgacaataa tttaagagag tctattgttg
    33241 tttatgctaa taatgtggat aatcagtatc atataaacat gactaataca aactttggaa
    33301 acataattaa catatgtaaa ttagaaaaac ttttagatgt ggataaattt atggaaaaag
    33361 ttataaaata tgaaaaagaa ataatagaga aagaagagtt ttcaaaaata gaagaatata
    33421 tgttaaatat tggagaatac taaaaaagtt gaaaaaaata cgaatgtttg atagaataag
    33481 taagtaaagt gttcgagagt atataaaata tagaggtgaa ttacatgaaa acagttgcaa
    33541 ttgttggttc tcaatgggga gatgaaggta aaggtaaagt tatagattat cttgctactc
    33601 aagcagatgt agtagtaaga gggcaaggtg gaaataatgc aggacataca ttagttgtag
    33661 aaggtaaaaa atacgcatta catctaattc catctggagt tttaaatcca aatacagtga
    33721 atataatcgg aaatggaata gtgtttgacc ctaaaggatt tttagaagaa ttggaaatgt
    33781 ttaaaacgga taatataagt acagaaaata taaaaataag tgatagagca catgtcatat
    33841 tcccatatca taaagaacta gatgcattgt cagaagaagc cagaggcgat ttaaagatag
    33901 gtacaacaaa aaaaggtatt ggaccttgtt atatggataa aacagagaga tctggtatta
    33961 gaatatgtga cttaatggat aaagataaat ttgctataaa attaaaagct caaatagatg
    34021 ctaaaaataa aatagttaaa aatatatatg gaaaagaaga attatttgat tttgaaacta
    34081 tatataacga atatctagga tatgcagaac aaataagaaa atatgtggca gatacgtctg
    34141 ttattgtata tgatgcagta agagcaggta aaaaagtatt gtttgaagga gcacaaggga
    34201 ctttattaga tttagattta ggaacttatc catttgttac atcttctcat ccaacatctg
    34261 gtggatttgc aattggtgca ggtataggac caaatatgat aaaagacgtt gttggtatag
    34321 taaaagcata tactacaaga gttggagaag gaccgtttgt tacagagcaa ataaatgaaa
    34381 ctggagataa gataagagaa caaggacatg aatttggggt aactactggt agaccaagaa
    34441 gatgtgggtg gtttgatgca gttatagtta agtatgcagc tagagttaat ggattgacta
    34501 gtatttcatt tatgttactt gatgtattaa ctggatttga taagataaaa gtttgtacgt
    34561 cttataaaat gggcgataag ataataacgg atttcccagc ttcattagat gatttagcaa
    34621 aatgtgaacc tgtatatgaa gaattagatg gatggaatga agatataact caaatagata
    34681 actttgatga ccttccagaa aatgcaaaga aatatgtagc aaaaatagaa gaactagttg
    34741 gagtaagtgt agatatggtt tctgttggtc caaatagagc tcaaactata ataagaagaa
    34801 atatatttgc ttaatatttt atcaattaaa taatttaaaa tagttgaaga agagtatctc
    34861 aagataatgt ttatagttat tagagatgct cttttatatt tgacttacat tgatttttta
    34921 ttaagttaaa gctacttata catattctag ctgaaattaa agttgaattt atgtagatac
    34981 atataggttt tttaaaaaga attttgttga aaataaatgg ctaaagatga ttttaattat
    35041 attctaaaaa aagtaaaaaa aactattgac taaaaattgt atagacgcta taatataact
    35101 tgtgagtgaa agaaacgacg aaaaaagtcg aaaaaatgtg gtctattagc tcagtcggta
    35161 gagcacctga cttttaatca gggtgtcccg cgttcgagtc gcggatagat caccaaaata
    35221 tggctcgttg gtcaagaggt taagacaccg ccctttcacg gcggtaacag gggttcaatt
    35281 cccctacgag tcaccagtat gggactatag ctcagctggg agagcacctg ccttacaagc
    35341 agggggtcac aggttcgagc cctgttagtc ccaccaaatt ttgaattaga gataaatact
    35401 agattatatg ctggtgtggc tcaacggtag agcagctgac ttgtaatcag caggttgtag
    35461 gttcgattcc tatcaccagc tccacaaagt acataaattc aaattaatat aattttctat
    35521 gttacaggat acttttaagt atcttttttt aatttcattt ttattgtatt aaaaatgaaa
    35581 ttaaacatac aacaaaattt tgaattactt gcaatgtgat agttttaaat ataaaattta
    35641 gaatcattct agcatagtat tatgtaatat agcaaattta atttatagta tcaataaata
    35701 tagactacta agaatgtaaa tgatttgtta gattaagata cattagatat gtaaatagaa
    35761 aaataaaaaa tatgttttaa tttatgtggc ataagtttta aacagagaag caagtttgct
    35821 cttacctctc tatttaaaaa taaaaaaatg ttttttaagg gctattttat ttaaatcttt
    35881 cccatctcaa atcatctcca gtaaattcta aaatcctaaa cttatctaag attctagaga
    35941 gagttctttg agtgtaagta tttcctattt gagatggtgt taagttggtt gaaataatga
    36001 tttttttacc agcaacaagt cttgtattta caatattgaa gatttcccca ctagtaaaag
    36061 aattattaag ttcagttcca aggtcatcta ttattaataa atcacaatca aacaagtttt
    36121 tataattatc ttcacttatt tggttatttg tgtctcttct aaatttataa tcttcaagaa
    36181 tatctaaaat tctaaaagaa gtttgataga ttacaacatt tcctttatct aacaattcct
    36241 ttgcaataca attgcacata taggtctttc ctagtccagt agaaccataa aacagtagat
    36301 tttcactatt atccttctta aaatcatgaa caaaattttc gcagatactt aaattattta
    36361 gcatattttc tctaggagat atttccccat cagagccttt cttaggagaa aatatattca
    36421 agttaaaatt cgaaaaattt tcctgactta aaatcctatc taaattagac attttataag
    36481 cttcatttac aatttcttgt ttgaggcaag aacatttttc tccattaggt aaaaatcctt
    36541 tatctttaca agaaatacat tgaaacttta tttccaagta atcaagaggt atgttacttt
    36601 cagataaaag tttttctttc tttactttta aagactctat attctcttta gtcttcttta
    36661 caatttcatc tttagatttg ggatttaaaa gtactatctt agctaaactg agacctattt
    36721 tagaaatttc atcatctata gattttatct cagggattct attatatacc tcattttttc
    36781 tatgttctaa taagagttca ttatcatctc ttctcttagc atatttagca agtatttttc
    36841 ttattttatc ctcattcatt taatcaccta cttaaacttt tctttttgac tttttttaat
    36901 aatctcatcg agctcatcag aggtatactg agtgaatgtt tcgttgaaat tatgaaactt
    36961 agtttttttg taagtattgt tgttttgagt agtattaatc tgcttcttat taatattctc
    37021 cttaactata cgttcttcct ctttttgctt taaatcattt aaatttttta tatttttttc
    37081 attccaattt ttaattatac catttatata agatatactt gggtttgaaa tattcttaga
    37141 cttagaacat gcatttatta tcaaatctat atccatatta aatttatcaa accaggtgtc
    37201 cataagttct ttttctgatt ttgatggttg tcttgaaaat cccaattcat tgaaaatcgt
    37261 tttatataaa atatatcgtt cacttcttac caaaaagctt tcttcaacat cttttggcgt
    37321 atataaattt gaatcatacc aatttctaat aatgccttca atgtatttaa ctggctttga
    37381 tgtaccagtt ttatctttga cgtattcata tgcgcaaagt atcatatcgg ggctcatatt
    37441 gtatttattc attatatcca taatactcat cttttcactt gggtcgagat atcgcccaac
    37501 tattttattt atagaattaa acatttttct aatacttgga ttttcagaag tagatacaac
    37561 cttatctgta ttagatttta tagatgaatt attgcttaat atattctcaa tatagaaatt
    37621 ttttaaatct aaaaattcta ttgaataatt aaaattatca tattctccat tgtcatgtat
    37681 ttttataatc ttcttttctt cccagaattt ccaagcagat aacacatcag acaatggtat
    37741 atttaggttt ttggctattg aattattgtc gaacttagga ttagaagtaa tatcacatgc
    37801 ttgtctatat cctaaaagat aaacttttac gtataacccg tccgccattg gcataaatat
    37861 atctataaag atattgggaa tagtgatttc acctaaatct atttcattgc tttctttaaa
    37921 aaacatttta tcacctcaga ttaaattata tcatttttta tattatattt gtctgtaaac
    37981 aaataaaagg tcacaagatt agcatgtaaa tattttctaa aagtattcat tttgaaaagg
    38041 aggagatatt ttggttataa aattcaacca aaaagtaaga agaacattat cagtagcgat
    38101 tctatttatg gtattaataa taggttgctt tatagaaaag gatgacagtt tagaaacata
    38161 caaagaaaaa actaattcaa aaataaatca gtataatatg gatgttatat ttgatgatga
    38221 gactaagagg ttaatgtgca atcagaatgt tgactacata aataatacaa aatcaaacat
    38281 agataaaata tatttccata tatatccgaa tgctttttcc aagaaagatt ttgctccttt
    38341 tgaaaaaagt gaaatgacaa gggcttatcc taatggattt aacgaaggat atatagatat
    38401 aaagaatata ttaaataata atagtaaaat ggagtataaa attaaaggag acaaaaatga
    38461 catattagaa atagaattag ggaaagagtt aaaaccaaat gaaagaatgt cattagatat
    38521 aaaatataac gtaaaaatac caaattcaat tggaagattt ggatatggag aaaatactat
    38581 aaatgttact aattggtttc ctatagcttg tgtaaatgat gaaaggggat ggaatttaaa
    38641 gagttatgaa actattggcg acccatttta tagtgagact agcgattttc atgtgaaact
    38701 attgattcca aataaatata aaattgctca tacaggaaaa cttattgatg ataaacatga
    38761 taataagaaa atgctatatg aaatagaagc tgaaaacgtt agagattttg catttatact
    38821 aagtagtaaa tttgatgtaa acaaagtaga ttcaaaggga gtagctatca atacatataa
    38881 tttaaataaa aagctttcta aaaaagcaac tgaagtggca aaagattcaa taaatatatt
    38941 tagtgaatta tttggaaagt atccttacaa agaattttct gttgtagcaa gtgacttttt
    39001 tatagggggg atggaatacc ctatgcttgt tatgatagac caaagtttat ataatgaaaa
    39061 aaatgaattt ttactagaat atgttattgc ccatgagaca gcacatcaat ggtggtattc
    39121 tgctgttgga aatgatgaaa taagtgaacc ctggttagat gaagcactta ctgaatattc
    39181 tacaatagtt tattttgaac aaaagtatgg taaagatatg gcaaacaagc ttataaaaac
    39241 tatggagata cagacaaaaa gttatttgag tgaaaatata tttaagccag caaatgagta
    39301 taaaaattct actgaataca gcttgaatgt ttatacaaaa ggcgcaatag catttaatga
    39361 aataagaaaa gaagttggag ataaagtatt ctttgagact ttaaatgaat actataataa
    39421 atataagcat aaaaatgcta atggaagagc ttttgtggaa ctatggaata gtaaaggtgt
    39481 agatataaat aagattataa gtgaatgtaa gtaaatagtg aatgtaagta aattttgtgc
    39541 agagtattaa attttattta atactctgtt tttttggtat aatataattt ataaggcaga
    39601 aaaagaggtg aaggaatgct aaagtattgt tcagtaggga gtggtagtag tgggaattgc
    39661 cactatatag ggtataaaaa tactaatata ctagtagatg caggattaag tggcaagaga
    39721 ataactacag gtcttaaaga cattggtgta gatgcagata aattaaaagg aatatttata
    39781 acacatgagc atgttgacca tataaaagga gcaggtatat tatccagaaa gttcgatata
    39841 ccagtatttg ctaatataaa aacatggtgt tctatgaagg acaaattagg tgacatcaaa
    39901 gataaaaata tgaaagtatt tgaaaatgat aaaacctact cattaggtga tatcatagtg
    39961 agaccttttt caatagaaca tgatgcgtct gatccagttg gatataattt ttatacagag
    40021 agtgatgaaa aaatgtctat agctactgat ataggatgta taactcaaaa tataaaaaaa
    40081 catctatata aatctaaatt agtagtattg gaatcaaatt atgaccctaa tatgcttatg
    40141 atgggttcat atacatatgc tttaaagaaa agagtaatgt caagtactgg tcatttatcc
    40201 aatgaagatg cagctaattt ctgcgttgaa cttattaatg aaggtacaga atctatatta
    40261 ttagcacatt taagtaaaga aaataatttt cctgagttag catatgagac ttcaaaagga
    40321 gtattagcat caaatgatat agtagttgga caagatgtaa aactagatgt actatcacga
    40381 aatgatgttt ctaatgttta tgagatgaag tagaggtgaa taactttgct aaagagaaat
    40441 tttgaaaatg ttgaggataa taaaatttta tactctataa agcagggtat gattttagca
    40501 atacctgcta ttatgactgg ttcaacggct cttgtaattt tgaatcttcc aataaaggct
    40561 tatcaagaat atttatcagg cttgtttaat ggagaggtta caaatattct taactttata
    40621 aatgattcta ctttaggaat tatttcatta ataatattat taacaataag ctatagttat
    40681 ggaaaaatat atgggagcaa gtatacagta cttgttccta tagttgcaat gtgctctttt
    40741 ttagtatttt cacatggtaa tgagcttaat tcttatatag aaatatttaa gacaaagtgg
    40801 ttatttacat ctataattgt ttctatgaca tcttctgtat tgtttgtaaa acttacagaa
    40861 tcttttgtta caagtgtaaa gtttcataca gaaggggctg atgcagactt taatatggta
    40921 gtttcggcta tagttccttt cataatagta gtatttttgt tttctatttt tagagtgata
    40981 atgataagtc taattggcag ttcaaacttt caagatatat tttataattt attttcaaat
    41041 gtttttaata aaatgggaac aaaccttatg agtgctctgt tgtttatttt tttaatgcac
    41101 tttatgtggt tttttgggat tcatggtagt aatgtattag ataccgtcgc aaaaaattta
    41161 tttgaaaata gtatggcaat taacataaat ttagttaata ataatcaatt accaacagaa
    41221 atttttacta agaccttttt tgatacaatg gttttattgg gaggatgtgg ctctttacta
    41281 tgtttagtaa ttgcaatttt tcttagtgaa aaacgtataa atgtaagaaa gctagctaaa
    41341 attgcttcaa taccagctct ttttaatatc aatgagatgc tagttttcgg gataccaatt
    41401 gtttttaact atattatgtt tgtacctttt gtaattactc ctataatctt aaccattaca
    41461 agttatgtgg ctatgtctac aggtattgta ccatgtacag tttcagctgt agaatggacc
    41521 tcacctatat ttttaagtgg atatatgtct acaggttcaa taagaggtag tttgttgcaa
    41581 gtatttaatt tatgtgttgg tgttatgatt tatattccgt ttataaaaat gtcgcaaaat
    41641 agatatacat atatgtttaa gaataatata gaaaatttaa caaacttatt aaaaaggtat
    41701 gaattaacag gtgaacagcc taatcttcta aaccataatg gtaaaatagg ttcaatttca
    41761 aaaatgttgg catcagactt gaagtttgct atgaaaagag gagaaataga acttttttat
    41821 caaccacaag tcaattataa tggaaatgtt gtgggagcag agggattact tagatggaaa
    41881 cattcaatag gagggttcat ttatccacca ctagttataa ttttggctaa agaagaaggg
    41941 ttcttagatg agcttggaga gtatattatt aataaagcat gtattgattt aaagaagagt
    42001 gaaaagctat tgagaaatcc tgttaagttc tctgtaaata tatctccaga ccaacttgat
    42061 gaccctaagt taccggagca aataaaaaat atcattagta gtaatgatat aaatcctaat
    42121 atgttaggta tagaaataac agagcaaatt gcattatcag gttcacaaat aattattgaa
    42181 cgtatcaatg cgatacataa cttgggaata aagttaatta tggatgattt tgggatgggg
    42241 catagctctc ttatatatct tcaaaataat aactttgata tagttaaatt ggatggttca
    42301 ttagttaaag agatacttac aaataaaaga agtagtgaaa ttataatgac tattgtaaat
    42361 ctttcaaaaa atttagattt tgatatagtt gttgagtatg ttgaaaatat agaccaaagg
    42421 gataagttat atggtttagg atgtgaaata tatcaaggat attattatag caaagcaata
    42481 ccttttgaag agtttgtaga atatgcaaat caagaaaaag agatataatt ttataagagc
    42541 ttgtaaattc tagtaatgca tagatttgta ataaaattaa gtttaggaga aatatatgaa
    42601 tataagtata gtagtagtag gtaaaattaa agaaaaatat ttaaaattag gtattgatga
    42661 gttcaaaaaa aggctttcta agtattgtaa gttagaaatt atagagttgg atgatgaaaa
    42721 agctccagag aatttgagtg ttaaggaaat ggaaattata aaagacaaag aaggaaagaa
    42781 aattttaggg aagataaagc ataatagtta tgttatagtc ttggctattg atggtaaggg
    42841 tttatcctct gaagaacttg ctaagactat gagtgattta gcagttagag gtaatagtag
    42901 tctctgtttt ataataggag gttctttagg gctttctgat gaggttttag gaagggctga
    42961 ttataggtta tccttttcta agatgacttt tcctcatcag atgatgagat tgatattgtt
    43021 agaacagatt tatagggctt ataggataaa taatggagaa ccgtatcata aataaatgat
    43081 acggtttttg ctaatttgac acttaataat attaaaataa caaaaaagta ttgaaagtat
    43141 attgcattta aggtagaatt aaataaaata ttataacatt ataatgttta tatagttgtt
    43201 aataaaaatt tggaggaaaa tatatgataa aaataatgtt ggcctgttca gcaggaatgt
    43261 ctacaagttt attagttact aaaatggaaa gtgcagctaa agaaaatggt atagagtcgc
    43321 aaatttgggc aataccagaa tcaactatac aaaatgaaat agaaaaatgt gatgtattat
    43381 tactaggacc acaagttaga tatgtattac ctaaggctca agaaattgct aagccatata
    43441 atataccagt agaggttata aatatgatgc actatggaac agttaatgga gaagctgttt
    43501 taaatagagc gatagaactt aacaacacta agtaatataa attataatgt atttttaata
    43561 tataaattgg gagaatcaaa ggatggatga aaagattata gaaatatctt ttaatataat
    43621 aggttatgca ggtgaaggta aagggttagc ttttgaagca ataaaagagg ctaagaatgg
    43681 aaatatagaa aaagcaaaag aattattaaa agagtctaag gaagttataa ataaagcaca
    43741 tagatatcaa acagaattaa tacaaaacga agctagtgga aacaggactg aaataagtgt
    43801 catacttata catgcacagg accacctaat gaatggtatg aattttcaac agttagctga
    43861 agaaatcgtt gatttacatt tgaaattaca agataaataa aaattaaaga gaataaatta
    43921 agagagttct taaaagatac attatgtgta gcacactaat tgttagatta ttgattcaat
    43981 atttagtgag taatacatta ggattatttt gaggactctt tttatattta gtttaaagtt
    44041 aataaatatt tattattaat aatataagat tatatgttat aatattataa catataattt
    44101 aagaggtgaa tcatgttaag aaatcaacca ttatatatac aagttgtaga tatattaaag
    44161 caaaaaatat taaataacga atataaaatt gatgaaaata ttccaacaga aagagaatta
    44221 gagcaagaat ttggagtcag taaaattact attagaaaag ctattgagat attagaatca
    44281 gaagggtatg tagagaaaaa aagtggaaaa gggacaaaag taataagtaa tagtcttttt
    44341 aataagctat caaaagcaga gtctttttca agtatacttt tatctaaagg tcataagtta
    44401 tctaaaaaga ctatttcaat tgaaaaaata ataaatgata caaattcaca agtatttagt
    44461 atatttggag aaaaatgtag caagattact agaatgtatt acttagatag taagccatat
    44521 atatttttta ctcattatat tccttttgat gaaaatctaa ctgttgaaag ttttaataat
    44581 gaaagttctt tatatatgta cttatatagg agaaatataa atataactag atttgaagat
    44641 gaatttttta tagaagaatc agaactagag gtatcaaagg ctctaaatct agctaaagac
    44701 atattattag gaagaaaaag aaagacctat gatgagaatg ataatatagt tgagctatca
    44761 tttgcaagat ataatacaga agtacaaaac tacgtaatta aatacgaaat ataataagaa
    44821 tcctgagttt attgaaatga taatatgctc aggatttttg tttagttgta aaaacgaaaa
    44881 atattataac attataatgt ttacaaccaa acattataat gttataatat ttttaataaa
    44941 taagtgatat tatcaattac ataaaaatta gtttatgtta tgaaatcgtt attgcattat
    45001 aaataaagga taatatcaat aatacagggg gataactatg gaaaaattcg caagtttttt
    45061 agagcgcaag attatgcctg tagcagcgaa gataagtaat cagagacata tgagagctgt
    45121 aagagcaggt ataatagcaa cattaccact aacaatagtg gggtcatttt tcacaatatt
    45181 attaaacata cctattgatg cttatatgga ttttatagct ccatttaaag caacattaga
    45241 tataccattt agatatactg taggattttt atctctatat gctacttttg ggatagcatc
    45301 atcacttgct aaaagctacg atttagatac aacaggtgtt ggtatgcttg cagttatggc
    45361 atttttagtt tctacaatag ttccaactca agtagttgaa ccagtaggtg gagttataga
    45421 agctggtaga tggatggata tggcaaaact taattcgcca tcattatttg gagctatcgt
    45481 aacatcatta attacagttg aaatatatcg ttttatgaag gaaaagaata ttacaattaa
    45541 gatgccagca ggagttccag tagaggtttc aaattcattt actgcattat taccgacagc
    45601 agtaatttta atgttattct gggtaataag acatatttta ggatttgata taagtgttgc
    45661 actaagcgct atgttatcac ctttaaaagg attcttatca ggaaatagtt taggtggtgg
    45721 gctactgaca gtattcctaa taactttatt ctgggtactt gggatacatg gtccagctat
    45781 aatggggcca gtaataagac ctatatggga catgtctata gcagaaaata taactgcatt
    45841 cacagaagga gtatcagctc atgcaatgcc aaacatattt acagaacaat ttttacagtg
    45901 gtatgtatgg atagggggag caggggctac tcttgcatta gttgtaatgt ttatgttttc
    45961 taagtcacaa tatctaaaaa gtttaggtag attaggattt ttaccagggt tattcaacat
    46021 aaatgaacct ataatatttg gagcaccaat agttatgaat ccaatactag ggataccatt
    46081 tataattgga cctataataa tgacaattct atcatatgtt cttactatta caggggttat
    46141 acctatgatg gtagcaagat taccatttgc aatgccagca ccaatagcag cagtaatgag
    46201 tactaactgg agtatactag caggtatctt agtattaatc aactttgtga tatcatttgc
    46261 tgtttattat ccattcttca aagtttttga aaaacaacaa ttacaaagag aacaagaaga
    46321 aatgagtgaa aatttataaa aatacataga tatagaggtt ttgtactata taaaatatag
    46381 aaaaagctta taagttatta agggtgaagg taggaggaat gacctttgcc tttaatttta
    46441 tatattttaa ataatgtaat ttgaggagga gaaagatgga aagaagatta ggaatatcag
    46501 tatatccaga gcatagtaac atggaagatg ataaggcata tataaaaatg gtttcaaaat
    46561 acggatttaa aagaatattt atgtgcatgc tttcaattac aagacctaag gaagaagtta
    46621 aaaaacattt taaagagatt ataacctatg caagagaatt aggatttgaa gtaatccttg
    46681 atatagctcc aaacatattt gatatattac aaatatctta tgatgattta acattcttta
    46741 gtgagttaaa tgctagtgga ataaggcttg actatggata tgatggaagt aaagaagcta
    46801 tgatttcttt caatccatat gatttaaaag tggaactaaa tatgagtaat gatgtagcat
    46861 acttggataa tataattact tacaagccaa atgtaaataa tatatatggt tgtcacaatt
    46921 tttatcctca aaggggtaca ggcttgccat atgatttttt tgtaagatgc tcaaatagat
    46981 ttaaaaagta tggaataaga actgctgctt ttgtcaattc aaaatacgca acaatcggac
    47041 cttggaatat aaatgatgga ctgtgtacgc ttgaaatgca tagaaactta gatattgcta
    47101 cagcaactaa gcacttattc gcaacaggat tgattgatga tgtaattgta ggaaatgcat
    47161 atgcaagtga agatgaatta aaaagaatgt ctgaagtaaa tgaataccaa gttgtattta
    47221 atgtagtagc taaagaaaaa acttctgaag tagaaaagat aataatggta aatgagcaac
    47281 actttagaag aggagatata actaatcagg tagcaagatc tacagaagta agaaaaaaat
    47341 atgctaaaga aaatttccct aaacatgata ataagaacat ctttaaaaga ggagatgtag
    47401 tgattggtaa tgatgacttt ggaaagtata aaggggaatt acagttgata cttcaagatt
    47461 gtacagatga aagaaaaaat aaggtgggta gaataaagga agacgaaata atacttttag
    47521 actttattga accttggagt aaatttaaga ttattttaga gggagagtaa agtgaagata
    47581 gacatattaa taaaatgtgg aaaaacagta gataaaagta taattgatat agctatatta
    47641 gacgataaaa taatagaagt aaaaaatcat atagatgatt ctaagtatca ggcaaaacaa
    47701 attataaact tagatggaga gaaatttatt agtgcgggtt ggatagatat acatacacac
    47761 tgctacgaaa gactagacct ttataaggat tatccagatg aggttggaat aaaaagtgga
    47821 gttactactg tagtagatgc aggaacaaca ggagctttag atataggtga attttatgaa
    47881 gatactaaaa agtataagac caatgtatat gctttaataa atattgctaa gcagggaata
    47941 acatctcaag atgaactttc aaatatgatg aatattgatg aatatgaact taaaaatgca
    48001 gttagaaaat acaaagattt tgttgttgga atcaaagcta gaatgagtaa aagtgttgta
    48061 atttcaaatg atgttgaacc tttaaaagta gctaaaagaa taaaaaatga acttaatcta
    48121 cctatgatgg ttcactttgg gagttctcct ccaacgatag aggatatatt tgattatatg
    48181 gaaaaaggag atatattaac ccatatatat aatggaaagc caaatggaat acttagaggc
    48241 aatgaggtta aaaaggaaat catagaagct aaagaaagag gtataattct tgatgtaggt
    48301 catggaaccg aaagttttag tatggatatt gcaatgaaat ctaaggatgc aggaattttt
    48361 ccagacacta taagtacaga tatatatatt aaaaatagaa taaatggtcc agtgtataat
    48421 ctatctacaa caatggaaaa gtttatatat atgggctatt cacttgaaga tataatagat
    48481 aaagttacta aaaatgcagc agatgcaata agtttaaaaa ataaaggttt aataaaagaa
    48541 ggatatgatg ctgatttaac tatatttgat gtggttaatg aagaaaaaga acttcaagat
    48601 tctttgaata agtcagtaat cacaagtacg tctataaagc caagagcagt agtagtcaat
    48661 ggagaatatt taaatatagg caactctata gaagagaatg agtagaaggg agaaactatt
    48721 gtatgagtag tatatttgaa aaatactctg taagacgtgt tataaatgct tcaggcaaaa
    48781 tgactatact aggagtatca acagtagata aggaagttat tgaagcaata ggtgaagggt
    48841 gtaaaaattt ccttataata gaagaacttg taaataaaac aggtgaatat atagcaaatt
    48901 tattagggtg tgaaagtgca ctaatagttt ctagtgcatc tgctgggatt gcacagagtg
    48961 tgggagcaat gatagcaaaa gatgatatga gtctagttta caatgtaaat aatcctaaga
    49021 aacaagttaa aagggaaata ataattccaa aggggcataa tgttgattat ggagttccag
    49081 tagaagtaat gataagactt ggaggaggag aagttgttga ggccggctat gctaatatgt
    49141 gtaacaagga acatataata agagagataa atgaaaatac agcagcaatt atgtatatta
    49201 aatctcatca ttgtgttcaa aagagtatgc taagtgtatt agatgcagta caagttgcta
    49261 aagaatataa tttacctttg atagtagatg cagcagcaga agaagattta aatgtatatt
    49321 atgaattggg agcagaccta gtgatataca gtggtgctaa ggctatagaa ggtcctagct
    49381 cggggttagt aataggtaag aaaaaataca tagataatgt aaagcttcaa tcaaagggta
    49441 taggaagagc tatgaaaata ggaaaagaaa atattgtagg tctaacatgt gcaattgaga
    49501 gatatataag taatgataaa gtaactttaa aagaaatgga ggacaagcta aatccattta
    49561 tagacaagat aaatactata aagggagtga gtgctagtat aactagagat tcagcaggta
    49621 gagaaatact tcgtggagaa attaacttta atgaagatat aataaataag tcaacacaac
    49681 aaattataaa tgaacttaga agtggagaga tagctatata cactagagac tataaggcta
    49741 atgaaggcaa gattgagatt gatataagaa gtgtaactgg aagtgattta gataatattt
    49801 ataataggat aaaaaatata gtagaaagtt agagtgtaga gtaagtgaca ttataatgat
    49861 ttaataaatt gaattttacc aatggagggg ataaatatga attgtatacc acaatattat
    49921 aaaaatagag tttgtttaaa tgttcttgca ggaagcataa aaaatgctaa agaagtatat
    49981 gatgcctgtg atggacatgt actagtagga gtactatcaa agaattatag cactgtagaa
    50041 gcagctattg aagatatgaa aaaatactca aaggaaatag ataatgcaat atctgtgggt
    50101 cttggagctg gagacccaaa tcagtcaaat atggtatctc agatttctaa agaacttcag
    50161 ccacaacata taaatcaagt gtttacaggt gtcgctacat ctagagcatt gcttggtcaa
    50221 aatgatagta taataaatgg attagtttct ccaactggta aaccaggatt tgtaaaaata
    50281 tccacaggtc cattaagttc aaaagaaaaa gatggtatag ttcctataga aacagcaata
    50341 gctatgatga aagatatggg aggaagctca attaagtttt ttccaatggg agggcttaaa
    50401 acaaaggatg aatatataga agttgcaaaa gcttgtgcaa agcataattt ttatttagaa
    50461 ccaacagggg gtatagactt agataacttc aaagagatag ttcaaattgc acttgatgct
    50521 ggtgtagaaa aagttatacc tcatgtttat acatcaataa ttgataaaga aacaggtgat
    50581 acgaaagtgg aagatatagg agtactttat aaaataatga aagaattatt gggatagatt
    50641 tatgaatata ttagcttttg gtgaaataat gatgagactt tcagtacctg actacaagtt
    50701 cttaacacaa accaatgaac taaattatat aattacaggc acgggattaa atatattatc
    50761 tggacttaaa aactttggat acaataccta tatgttgaca aagttgccta ataataatgt
    50821 aggtaaagca tcaagtgcaa atataagaaa gcttggagta aaagatgact ttatcacata
    50881 tggagggaat catataggag tgtattttct tgaaaatggg tatggagaaa gaccttctga
    50941 agtgacttat ttgaataggt taaatagttc attttgtgag agtaaattac aagattatga
    51001 tattgataaa tgtttagaag aaatggatat agtccatatt tgtggtattg ctatgcaact
    51061 tacagattca gttaaaaaga ttgctttaga actagctaga aaatcttatg aaaaggggat
    51121 aaaagtattc tttgatttta attttagaca atcattaaat ccagaaagga cttatgatga
    51181 tttagtaaat gattataaga aaatactacc atattgtcat gggctgtttg ctagttatag
    51241 agatataaat aagatactta atatagatag tctaaatata aaatctagtt cagaattgat
    51301 taaaaaagag tatgatatag atattgtagc tggaactatg agaagatttg atgatatgaa
    51361 taatagattt ataaagggat atatatcaaa tgatgatggt tattttgaaa gtagggagta
    51421 taagttagaa atatatgaca gagttggtgc tggggatgga tatgtggcag gaattatata
    51481 ttcatatttg gaaaatatga agagtgaaga tatagttgag tttggggttg ctagttcggt
    51541 gttagctcat acaacttatg gggataattc tttagtaagc acaggtcatg tacttagact
    51601 gatgaacaat gaaaaaatag atatattgag ataatacatt tgtatataat aaaattttta
    51661 tcttttttag acacactttt gacttgctta tatttgttaa acagagttat ttttaacgat
    51721 tataaatatt aaattaaaag ttagataata aaatagtaga aaatagcatt aaccatataa
    51781 aaatggttaa tgctattttt atagttaata ttgattaatt ttatattata gaaatgaact
    51841 tttctaatgc tggatttgta ttttttttat tccatacaac cacaacttca attctatttt
    51901 ctacttcttt tataggtact attgcaatat cacgttctat cattgtatct gtaacacaaa
    51961 atgaaggtaa aatggatatt cccatgttag aagataccaa tgattcaata gtattaagat
    52021 tatttgaacg ttgtaccaca ttaggtacaa accccgcttc acgatatcta ttttgtatca
    52081 ttgacttttg tccatactca tcccctgttt cttttacaaa aataaattta tcatgttgta
    52141 attcaattaa atcgatagaa tcctcattgt aaagtggatg accaggaggt aaaagagcta
    52201 ccaaagaata tctttctaca gttttatatt caaaatcttt taatggttga ttttctggat
    52261 taataacaaa agcgaggtcc atagaattat tttttactaa gtttaaaagt tcggttattt
    52321 cattagtaca aatatccata gatatattag ggtatgtatt agaaaattct tttaagtatt
    52381 gttgaagttt gtttttttca tatcctatta aggttccaat gctcaaagtt ccaaaaaaac
    52441 catgtgcaaa ttgttgtgtt tttgcaatag catcattgat attttttatt atagtacgtg
    52501 cctcagataa aaaaactttt ccggctggtg ttagttcaac atgacgttta cttcttgtaa
    52561 atagagttac atttatttgt tcttctaaag cttttatttg ctgtgtaaca gcagtttgag
    52621 aaatataaaa tttttctgct gttttggtaa aacttagatt ttctgctaca gatataaaat
    52681 attctaattg tttagtattc aaataatcac ccctatttaa acttgattgt ttgtaaacct
    52741 tatttatcta taattaaagc ttattatagt ataagaaaat ttacttttaa agaatattag
    52801 aaaatatttg tataaaaata tatgttttaa gtatatcttt acattagatt ttataaattt
    52861 attaataaga ataacttata tattccaatg aaaacgatat tggatttaag taagtttgtc
    52921 tcataaaatg aaagtatatc aattgataat actttaaata agaagggaga aaaaatggaa
    52981 gataaatttt atgcaaaagg caacggaaat aacggatata ttaaaaatct tgaagtttgt
    53041 tcctttaata acttagatgg aacttgtgga atgtttcaaa tggctctgta caaaagagat
    53101 gaaaaatact atttatatgg atgctgtttt ggaggaaata aaaaaaatgg agtaatgatt
    53161 agcgatatta cagaccctta taatccacaa tttataaaac attttcaaat gttagaccct
    53221 aaagagtatc ctacaacaac aactccaaaa attcaaatag cagatgattt aatgatagta
    53281 gcaatgagtt gtggaagtgg accaggagca cttgttgacc aagctaaatt agcaaatatt
    53341 aagtgtgaag caggaattag aatatacagt ttaaaagaag accctttaaa tcctaagttt
    53401 ttaggatatt gggattgtgg cttaaagcat gtaatgggtg ttcatagatt catgtacaat
    53461 ggtggaagat atgtacattt atcaagtgat tgtgttggct ttgaaggtct gatttatagg
    53521 gtcatagata taataaatcc taataatcca gtggaaatag gtaaatggtg gagaccagac
    53581 caatatgcag atggatatcc aaatagaact tttgatgcag gagcacctca ttgcccagaa
    53641 tttatggata aaggatggct tcatggacct ccatttgtaa gagacggaaa agcatattgt
    53701 ggttatggag gagctggttt agttgtatta gatgttgaag atttaacaag accaagatgc
    53761 ttaggtgaat tgccatttat gcctgcattt tctagtagac ttgcaggtgc aagaactcat
    53821 acagcattac cattgccagg aagagattta gtcgttgttc aaaatgaggg agaaagattc
    53881 cagttcttta aaccagataa cattacagat gttcaagcta tgaataatat acatatggtt
    53941 gatgttagtg acccaacaaa accaacatta attgctcaat tcccatatcc tgaagttcca
    54001 aaagatttcc cttatcctaa ctttaatgtt gcaggattag gaaaagcagg gccatttggt
    54061 ccacataatc ttcatgaacc aatggataat aagccatggt tagagcaaag aggagataga
    54121 gtatattgct gttatttcca tgcagggcta agggtttatg atgtatcaga cccatattat
    54181 atcaaagagc tagcatattt tataccacca aatccaaata aaacaccaga agaatcttat
    54241 ttcccaggat tcccaggacc acgcttggca gtaacagaag atcttatcgt tgatgataga
    54301 ggctacatca tcatagatgc tttagatgat ggattctata tattaaaaat gaaagaagat
    54361 taaataaata ctaaagaggg agagttgaaa atgaaaatac taggtatttc ttttggaaca
    54421 aaaaatggaa ataatgacac aatgtgtaaa gttgcactta aaggtgccaa agaagcaggg
    54481 gctgaagtag aatttattca aatgtcatct attaacatta aacattgtac tggatgttgt
    54541 gcgtgcgtta aaactttatt atccgggaaa ggtagtatgt gtgtattaaa agatgatttt
    54601 gaatggttgc ttgacaaaat gaaagatgca gatggtatag tagtttcaga ccctattttt
    54661 gaagaagggg catcaggatt attccatact ataatggacc gttttggacc cagagcagat
    54721 agaggaaata acattatagg aacaaaagtt gcagaagcta taggaggaaa aattccagac
    54781 tcaagaatgc ttaatgataa agtaatatca tttatgggaa taggaggttc tgactggggt
    54841 acaagagttc aatgtgaaca tgctatgcta gctctcatac caatgtggaa agttatagat
    54901 aatgcttggt tcccatgggc aaaggaatta gtaatggatg atacaaggct tgttcaagtt
    54961 catcaaattg gtttaaatat agttgaagca gcaaaagatt ttgaaaaagc ttcatatcaa
    55021 ggagaagaag gtgtatgtcc acattgccac aatagattat tctaccttga gtcaggtact
    55081 aaaaaggcaa tttgtgctct atgtggtata gttggagagt tagatactat aagtggaaaa
    55141 actatattta gttttccaga agagcaatta ggtcatgctc atgatacttt accaggtaag
    55201 tttatacatg gtgatgatat taagaaaatg gaaggtcatt atgcagaagt tcgtaaaaca
    55261 caagaattta aagaaagaaa aacatcttat aattttatag agccattaac taaagaaaag
    55321 caagctggag tttcattagg ataataatta aaatactaag actctttttt aagggatgtt
    55381 agatgttata ggaggcttat tgtatgaatg aaaagccaag ttttaaacaa attgaaatta
    55441 ttttagcagt tatttttttg gtacttacat attacaagat tggattaact ccagcattta
    55501 ttgttatatt tataccatta tacttaagtt attttgcagt atctatgatt gtaaatcaaa
    55561 tagcaattaa gctattggag ataaggcaag ctagggaagc tactaattac aatataggaa
    55621 atggatagaa agaaaaaaga aatattaaca ctgtctatgg ggattgcttt actacctcct
    55681 ttatgggcag tattagcacc ttatatagga ataaaaactg gagctgtagc actaatctgt
    55741 gcaggattat atgtaactaa tggtaataaa caaaaagatg gattaaaaat aatgtttggt
    55801 ttttggtgtg gagatttatg ggcagtgtta gccattttaa ttatgggata tatgaatttc
    55861 aatcaaaacc tagaattatt tttaacactt agtatattag gtttttttgc agttgtaatt
    55921 gcatccttat ttgaaaaaat aattttccta ccatcatggc tttgtggttg ggctataggt
    55981 ctaactatta tgacaggtga aaatattatt aatttacaag atatttgtat tcaaattgct
    56041 gtagctatgg cagtaggagt atggtacgtg ggtgcaggtg tagatttgtt tacaatatat
    56101 attttgagta aagataagaa aaagggaaat tgaaagcatg tgaatatact ttgattatag
    56161 gagaatggct atgggttttg aatttaaaat aatgagaagt ttaatatatg taggacttgc
    56221 caaggaagaa tatagaccta agttaatgga ctggttatat cgtcaccata ttccagatag
    56281 tattagcact tttggaccat attgtactaa atatgccttt tatcaagcat atcctacacc
    56341 aaatgaaggt gagcgttttg gtgcacgtaa gatgcaacta acagaacatt attggcttgt
    56401 agatgaacat atgcctgaga tggcaaatag aattatgaca gaatatatgc ctatggatgt
    56461 tctacgttgg caagggtgta taccagatgt agaaaataaa agggttcatg aaaatgcaga
    56521 aagtggagat gcaggacgtg cagtaggtgg agataatgga tgcccaccat ttatatttgc
    56581 ttttgttcca ataaactggg aagaagactt tagaggaaaa ggacgtactg tacaagatgg
    56641 accaaactat cgttggcaat ttatgattaa gtatccagat ggtatctcta aagaagaagg
    56701 agaaaaatgg ttctatgatg aggtagtgcc atactttaca aactgttgct atgttaatcg
    56761 ttttgtcagt agtaaaataa tgattaatta tggagcaact gcttttgacc gtgtatcaga
    56821 actatggttt gaaggggaag aggaatggta taaagctgtg gttgaagaga caaagtcgtt
    56881 tattaaaaaa ccagaatggg cacaagaaga ggagttccca tatttaaaac cacaattcaa
    56941 tatcgcatca gtattcttag gtgatatagc aactatggat gcatactcac agtatcgtgg
    57001 atatatacca atgagataaa aattatagtt tgtgataagt agaggaagta cttactctta
    57061 ctgctagaag aagacttatt gtacacttaa aagaatgaaa tagataagtg tcaatttatt
    57121 atatgagaga aactttaact ttcttggttt aaaatattaa agtcataagg aacatttatt
    57181 attaaatact ttatttatat gaattaattg aagaaaaagg atattaaact acaagttaaa
    57241 aaataaattt aatatattag aattataaat aaggcacatt aattttattt taaattaatg
    57301 tgccttttat ttatggtaat ttatgcataa ttagtatcgc tttgattctt taaataaatt
    57361 ttttttggtt tctttacata aggaaccctt ttttatttat aaaatctata agtgtaatat
    57421 agtagctatt ttagataagt ttaatttttg tctcaatcta aaacaaaagt tatacttaaa
    57481 tgaaattgaa aacgataaaa ttctcaaata aaataagtat tgtggaggtg atgaaagaat
    57541 ccaatgataa tatgaagact aatcttaata agaaagtagg ggttaatggt agtggacaaa
    57601 gaaattgtat caattctcca gattttatta aatagcacat tgattacaac taatggatta
    57661 caagaggagt ctaattcatc aaagagacaa attacttata gaataaataa aatcaatgac
    57721 atgcttaaag taaaaaatgt accacttata tgtttaagag ctgataaaga tattatcgtt
    57781 agaaaagaaa caaaaaaagc aattaaagaa attttagaaa aaaactattc taagaatact
    57841 tattatttta gtaagacaga aagactttta tatatgtatt taatgctttt tattaacatg
    57901 gaggatattt caattaatca ttttataaat tctataaaag taagtaggtc tactgtaaat
    57961 cttgatttca aggatttgat accagagctt gaaaagaaga acattaaagt taagaacaat
    58021 cgtataaatg gatattacat agttggcaat gagatggaaa ttaggagagt gcttattaaa
    58081 aacattatag aaactttgtc taatgagaaa agttcaagag tatttgatat ttttattaaa
    58141 gaatataatt tagatagttt tgaagaggct aaaaaaatta tattaaagct aataaaaaaa
    58201 tatgaaatta cttttgttga agatagatta atagaattta tatatatatt tatctttcta
    58261 aaagcaagga tgtattcaac tagaatagtt actcaggaaa atgtagatat tcctaatatt
    58321 tcagttatga gttcaatgaa ggagtataaa tttgctaagg aattattaga agtatatggg
    58381 agtgaggata agataaagcc ttataatata atgtatatta gtgcttggat tttaggtata
    58441 tcggtaggaa attatgaaga agatacagaa gataaggatg taatttcaaa aattgtaaat
    58501 aaaatgatga caaagtttgg atatttaagc ggagtttact atataagcca agaaaaaata
    58561 tttaaacaat tatattctca ttttagacct gcctactata gacttttatt taaattacct
    58621 atctataatc cgatttgtga aaaagtaaaa gaagaatata aattagttta tagaattgta
    58681 agtaatgcaa tgaaagagtt ttgcggatta tttggagaag aaattcagga agaagagtta
    58741 gcatatctta caatgcactt tgcaacactt ttttcaaata aaaaagaatt tgatggtttt
    58801 agaaaaagaa tagcattaat agtttgttca aatggcgttg gtagttcagc tattttacat
    58861 gcagaactta caaacttatt tcctgactta cactttatac caatgtcgga atcagttgga
    58921 ttagaaaata taagtgaacc tgtagatatc gtatttacta ctaattataa cgcagagggt
    58981 ttaaaaacag atgtaccagt aattaaagta agccctgtta tgaccacaaa agaaaaatat
    59041 aagattacac gtgaagtgta tattcaatta ggtgatattt atttaagaca acctaaaata
    59101 gatgaggtta tggatataat aaaaaaatat gcaaatgtaa cctctgaaag tattctttca
    59161 agtgagctat tagcttattt tacacagata gagaatttta catctaagga aggagagggg
    59221 cctatgctaa gtgagattac taatgaaaca ctagtaaaaa taaaggtaaa agctaagaat
    59281 tgggaggaag ctattagaca gtcagcttct gtattagttg aaaataacaa agtaactgaa
    59341 gggtatgtag atgctatgat taactcagca aaagcatctg gaccatacat agtaattaca
    59401 aaacatgttg cacttccaca tgctagacca gaagctgggt caaaagagat tgcaataggc
    59461 attgctactt tagatagtcc tattgagttt gggaataacg aaaacgaccc tgtaaaatat
    59521 gtattttgtc taagtgcaat agacaataat agccatttac gtgctatgtc tgagctagtt
    59581 gaactattgg aagaagatga gttttttaag gttttagata gtgctaaaga ggctaaagaa
    59641 attattgatt ttataaaaac acacgaatta taaaggagga tttaattatg tataaaattt
    59701 taatcgcatg tagagcagga gttggctcaa gtttaatgtt aaaaataaag actcaacaaa
    59761 ttattaagga aaataacttt ccaattgaag tagaacatgg ttcattggat tcactaaatg
    59821 gattcaatgg agatgctgta gaaacattaa ttgatgttgc tgaagaatta aaaaataaaa
    59881 atttgaagtt tgatataatt gggattcaca atattgttga ccgtaatgaa ataaagacag
    59941 cactagaaaa attccttgct tcaaaagagg gataaattta atatgataag gaggaatatt
    60001 tatggagttt attattagtt tgctgagtac acctgctgtt ttgcttggcg tagttgcatg
    60061 tataggattg attcttcaaa agaaatcagc cgttgaagta tttacagggt cttcaaaaac
    60121 acttatcggt tttttgatat ttggtattgg tgcctctgct atgacaggag cacttcaaaa
    60181 tttcaataaa ctgttccaac atggctttgg aattactggt gttatagctt caccagaagc
    60241 agctacagca cttgcacaag gtacatatgg ttttgcagtt tcatgtacat taattcttgg
    60301 attcatatta aatttagtat ttgcacgtat tacaaagttt aagaatattt tctttacaac
    60361 aggtcatagt ttattctttt cttgtgtatt agttttaatc atgaaagcac atggatttga
    60421 taatacaatc actattttaa taggtggaac tatcttaggg tttatgtctg ctgcactacc
    60481 tcaattctgt caaccattta tgcgtgaatt aacaggtggc gacgaacaag ctattggtca
    60541 ctttaacatg attggttatg gtttatcagg ttatattggg cgtttatttt caaaacataa
    60601 agatgataca acagagacta tagaatttcc taagtggtta tcaatattca gagacttctt
    60661 aatgggtcta tccatagtta tgttaatctt attctatatt gcaacattaa aagctggtca
    60721 agcatttact caagaaattg ctggttcaac acattggttg gtttttccgc ttatagaggc
    60781 atttacattt gtggcaggta tgtcaatatt gatgtcaggt gttcgtatgt tcttagctga
    60841 aataactgca gcatttgtaa tcatttcaga aaagtatatt ccaggttcac gtcctgcgct
    60901 agatgttcca acagtatttc catatgcacc aaatgcagtt attattgggt ttatatcagc
    60961 atatgctgct ggtctattag caattgctat tatggcatca tttcctagta tatttcctgt
    61021 agtaattatt ccagctgctc acatatgttt cttctcagga ggtacagctg caatatttgg
    61081 caatacttca ggaggatgga gaggggctat tgctgggtca tttgttgttg ggttattact
    61141 tgcattttta ccagttatac tatatccagt ttatgggact cttggtatag aaggagcaac
    61201 tttccctaat attgattaca acgtagttgg ttcgatatta cataatattt tacaatttat
    61261 aaaacctatt taaactaaat tatataaaag tatagtcata gttactatga tttcaaggag
    61321 gatacatctt atggaaaata cattatctga atttttagat aatatatcta atgaattgtc
    61381 agaatttatt gcctcaatag atgagacatc tataaataaa gcatgcgaat taattcttga
    61441 agctgaaaaa aatcacggac gtgtacatgt gactggtatt ggtaaaccag gacatgtatc
    61501 aggatatatt tcatcattgc tttcatctac tggaacatca gcatatatat tgcatggtac
    61561 agaagcagta catgggtcaa gtggtcaagt agttgaagga gatgttgtta ttgcaatatc
    61621 aaatagtggt gaaactcaag agttaaaagc aactcttaag actctaaaag taaatggagc
    61681 aaaaataatt ggtgtaagtg gtaatgagag ttcattttta aaaaatattt ctgatatatt
    61741 cctgttcgca ggcgttaaac aggaaggaga ttgtcttaat aaagctcctc gtgcttcaat
    61801 tttagctgaa acaatagtat tacaatcatt aagtgttgta ttacaatatg ctaaaggtct
    61861 taatacacag cagtatttga aatggcatcc agcaggaagt cttggaaagt ctattagaga
    61921 gggaatataa ttttatgaaa tataaaggga ttatatgtgc aatgataaca ccatttgatg
    61981 aaaagcaaaa tattaattca caagcaacat gtaaattaat tgattatttg attgaaaagg
    62041 ggatttatgg attatttatt ttgggtacta atggtgaatg tcatgtgtta acagatgatg
    62101 aaaaagttga atttgcaaag attgttatta atcatacaaa taatcgtgta cctgtttttg
    62161 ttggaacagg tggtaattca actcgtgaag ttatagattt atccaagaga atggaagcga
    62221 ttggagcaag tgcattatct attattacac catactttgt tacaccaaca caacaggaat
    62281 taatcttaca ttacaaaact attgctaatt cagttaattt acctattata atgtataata
    62341 tgccaggtaa gactggaatt aatattgaac cagagtcagt acgtgaatta tcaaagataa
    62401 agaatattgt tggaattaag gatagtagtg gtaaacttga caacatgaaa gcttatattg
    62461 aagtaacgca gaatgagaat tttagtgtgt tttcaggctc agattcactt attctggata
    62521 gtctaaaagc tggtagtcaa ggagctgttg cagcaacaac aaacttcctc acagagattg
    62581 gtatttctat ctatgaaaac tttatgaaag gggatttgga agaagctcaa aaagctcaaa
    62641 gtagtataga agaacttcga cgtatactaa aacttggaac aattccatct gttatgaaga
    62701 aaactattgt cttgaatgga attaatgttg gaactgcacg acttcctgta actgaaccaa
    62761 ctggggaagt acttgaagaa attaaacgag tagttgaaaa ttataggaca atacttaata
    62821 aaagtagtga gaatagataa tataaatagg gaaattacac tggtatataa ttaatatata
    62881 tattataaaa catgactaaa attaatgaat aagtaaagtg gtttgatgag tatagaggtg
    62941 ataatatgaa aaagatgaat ataaccaaaa gaatgtcaga atgtggggct cttgcaattg
    63001 taagagaaga aaatcttaac cgtgcatgtg aaattgctga aggatgtata aaaggtggta
    63061 taacagttat agaaatgagt tataccctaa ataatgctgg agaaataatt caagggctta
    63121 ataaaaagta tggtgaaata ctttgtgtgg gagcaggaac agttttggat agtgaaacag
    63181 ctcgtcatgc tatattacat ggagctcaat ttattattgc accaaattac aatgaaggtg
    63241 tagcgaagat ttgcaataga tatcagattc cttatgctcc aggatgtaca tcattgactg
    63301 aggcagtaga tgcactaagt ttaggagcga cttttataaa agctttccca atatcagatt
    63361 tctatggacc taaactagta aaggtattta agacaccaat acctgatatg ccagttttag
    63421 caagtggagg aattaatctt gaaaacctac atatatggtt agaaaatgga gttgatgtat
    63481 gtggatttgg tggtttatta actaaaggaa ctattgagga tattactgaa aatgccaaaa
    63541 agattcgtga aatcattaaa aatataagag aaatttaaca tggaggatga attagttttc
    63601 tattgacgag atatccacac attaattcct aagttagaag aaatattttc tagttgaggt
    63661 aaagtttata ttgaacttaa attaaatttt gttttaaata agatattatt ttagttgatt
    63721 gctaaaaata ctagaatcta tattaatgaa ttatactaat tttgtaccac tattaaaata
    63781 ttgtttgcta aaaataaaaa ataaccttaa aacagttgat tataaaaaat taactgtttt
    63841 aaggttattt ttatctttgt gacgaaatag acacttgcca tttagaatgt gacaatatag
    63901 tagttgttta gaaaaggtac aaagcattat actttaacta aagtaaaata tattttgctt
    63961 ttagaataaa aacaattagg agggagctat aattgaaaaa gataatatat gtattattta
    64021 caattgaact attaatagta tctttattag gtctaaatat agttaaagat aatgaaatta
    64081 ataatatttt atataacgat acaacaagta tatctgtaat gtttaaagat tataaaaagt
    64141 taaataaaaa ttatagtaag tggattaaag atattgcaga tgaaaataat gtggctatat
    64201 caaagtatgt ttttaataat aatgaaaaat tatctatata tacgactgat acaagtttga
    64261 ataacaatat aaagttaaaa tcaggaaaat ttcctaatac taattcaaat gaatttatta
    64321 gtaatataaa cactaataat agtaataata gtaatcaagt aggtaaattc tcaactatga
    64381 gtaaagacat atcaatttta attagggatt ttggtaaaat aagtgaagtt ggagaatcag
    64441 gaatcttata tatttcaact caaaatgaag atacaataaa taaaatatta agagaactaa
    64501 atgtagacag aagtattttt gtagcaagat tacatgatag atatgttaac tcaaatttat
    64561 acttaaatcc ttcaataatt agagatttaa tactaattat cctttgtttc ttggctacaa
    64621 taatacatta ttcaattagt gtgagtagag aggcttctat tttaagatta aatggatact
    64681 ctaagctaga tataattgct agggttataa aaaatatatt tagaattatg attttatcat
    64741 ctgtcacagc attattaata tatataatct atattttaaa attaaatata ggtgttagag
    64801 catgcttata ctttgctatg ttttcgatta tatgtatttt gataaatatt ttgatatcta
    64861 tattaatagt tggttttaat agtagaagtt ctaaatatgt gctatctcta aatggaaaaa
    64921 aatcttatgg ttttgtaaat ataatgcatt tcacattgaa aattgtattt gtatcatttc
    64981 ttatattatc cataaataac tgtattttaa attataatat gctacaaact cagttaggaa
    65041 atctatctga gtgggataaa gcaaaaaatg tttataatct tactcttaaa gatacaggcg
    65101 aacaatcttt aggaaaggaa gaagtaatta aaaatgccaa gattaaaggt ttctataaaa
    65161 atttggtaga agaaaaagat gctttcttaa tagattcaac taattttgaa aaacttgaag
    65221 atggaagtta catgtatgaa ataaattcaa agggtaaaaa cccagaagta agtcaatatg
    65281 gtaaaaatat aaaaataaat aaaaactatc ttaaagttaa ccctatttac tcaaatggca
    65341 aagaaatatt taatctaatc gattatgacg ataagactat aaatttatta gttcctaaaa
    65401 agttacaagt acatgaaaat gagattaaaa aagagtttag agaattattt tattttgaaa
    65461 aaatagaagt agaaaatatg tacaataaag agttaaatag agagttaaat aaaacaaaga
    65521 agtcagattt aaatgttaat ataatatatg tagataataa tcaaagctat tttacttata
    65581 actcccttgt tatggatgac aataggaatc tcattgatga cccaatagca ataattgaca
    65641 tagataatat tgatgattct ttttatcttt cttatatatc tagatgtgta tattttaatt
    65701 ctaagaaatt agatgccctt gcagatataa gtaacattat tgaagctcaa ggtgtagaag
    65761 cgcatatcca aagtttacat gctgtttata atgagtatgg tttagaaata aataaactag
    65821 aaaaatattt gaatagtgaa atttttacta taataataat agcaatatca aacttaatga
    65881 ttacctacaa tatagtagct agctactatg aaagaaataa atataagtta tatattaaaa
    65941 aaatatttgg ttattcaact acagctagaa gtatgttgtt aatagtctca ttaatattaa
    66001 caaacattat tccaataggc attatatcaa caagagtaga tttaagtaat aatattatct
    66061 tatttggact tctgatatta gttatagaag taattgtatc tattgtatta gacaagatta
    66121 tctcaaatag ttcatttaat aaaattataa aaggagaaca ttaaaaagat gatttcatta
    66181 ataaatatat ctaaaaaatt taaagataaa tctataatag acaaatttaa cctagaaatt
    66241 tctaagggcg agtttgtagc gataacagga aatagtggtt caggtaagac aactttactt
    66301 aatataatgg gattattaga aaaacctaat tctggtgata ttataataaa taatataaaa
    66361 aatccaaata gtaaacagat aagaatttta caaagggatt tttatggcta tctatttcaa
    66421 aattatgctt taattgagaa tgaaaatgtt gaaaataact tgaaaattgc tttaaagtat
    66481 caaaaaaata tcaaccataa tgaaaaaata aattacgcac ttgagtctgt aggtcttaga
    66541 aaatacaata aaaaaaagat atacgaattg agtggaggag aacaacaaag ggtagcatta
    66601 gcaagagtaa tattaaaaga atgtgaagta atatttgcag atgaacctac aggtaattta
    66661 gataaaaaaa atagagacat agtatttgat atacttaaaa atctaaataa gaatggtaaa
    66721 actatcgtat ttgtaactca tgatttagag ttatcggagc aggcagatag agttataaaa
    66781 ttgtaataat atcaactata ataaatataa gaaagagatt acagctaaat caagtttaat
    66841 aataatacga atagaattta aacattaagt aaattagtag tttgtaaata taagtataat
    66901 atgatatcat aaaggctcaa aagaaatttt atataataag aaatttaaaa ataacaaatg
    66961 gaggacatat aaagatggaa aatttaccaa attgcccgaa atgtaattca gaatatactt
    67021 atgaagatgg aactctttta gtttgtccag aatgctctca tgagtgggca ttaggattgg
    67081 gagctgaaga agattcaaat attatcaaag atgtaaatgg aaatgtatta aatgatggag
    67141 attctgttac agtaattaga gaccttaaag taaaaggaag ttcatcatct ataaagattg
    67201 gaacaaaagt gaaaaatatc cgtttaatcc atgactcatc agatggacat gatatagaat
    67261 gtaagataga tggttttgga gctatgaagc taaagtcttc tgttgttaaa aaagcgtaat
    67321 attataaata agctgtagtg tttattgttt ttcagtacag tataaaacca taagaatcta
    67381 ttaagtaata aaagtttgtt tatttatctt tatattttct tatggtttta ttaaatataa
    67441 attttattga acaccaaaat attctctcct ctacaaataa gccaatctta tttaaattaa
    67501 tatactttgt actatttata ctgaaattgt gaatttaaat gctatgttat ttaggtttgt
    67561 atagttaatt tatatatttc tgattttata aattgtattt attattatat cttgattcta
    67621 aaatcattaa aaatttcaac ttctataaag atttacaatt tatcaaatac attatgagta
    67681 tataaacaat ttattattac agtgctacat ttaaaataag tcttagtata aaggtattgt
    67741 tacaagtata aagaaactta tgtatgctat tggaataaat aataccttaa attataatta
    67801 agaataagaa ctgttaaata agggacttga ttatcattta gttatagata atataatatt
    67861 aaaaataaag cttaagagga gaaaaaatat gatagatata cataaaaata tatatgataa
    67921 taagttattt gaggagctaa agattgattg taagaagtgt tttggacttt gttgtgtagc
    67981 tctttatttt tctgcttcag atggatttcc tatcgataag gaatcaggaa aaccctgtat
    68041 taatttacaa ccagatttta aatgttctgt acataatagt cttatgaagc gaggttttaa
    68101 agggtgtact gcatatgatt gttttggttc aggtcaaaaa gtagcacaag taacatataa
    68161 ggggatagac tggatgcaat caccagaatt aacaaatcaa atgtctgaag tgtttttaat
    68221 tatgagacaa ttacatgaaa tgttatggta tcttaaagaa gcatctgtat taaatatatc
    68281 agatacaatc aaatcaaaaa ttgatttgat aattgaagaa actgaaaaga taactaatat
    68341 gagcccagaa cagataatta atttggatat catatcacat agaacaaagg ttaatttatt
    68401 attatcacaa gcgagtgagt ctgtgatggg aaaggttaaa tcatttatca agacttctac
    68461 tcttaaaaat atgaaaaaat taagtaaaaa tatagattta ataggagcag accttagaaa
    68521 aataaatcta ataggagcag atttaagagg tagatttcta atagcagcaa atttaagaag
    68581 tacagatttg agtggggcaa atttaatagg agcagactta agagattgtg atattagagg
    68641 tgctaatctt gaaaatagta tatttttaac acaattgcaa gtaaatactg caaaaggaga
    68701 ttctagtacg aagttaccag cttcactaat acgccctaaa tactgggaga aataattaaa
    68761 ttaatacata attttacaaa atatgaactt ttttgacttt aattcatatt atacattaga
    68821 gattctttac aagaatttct taatataata tagggagaga tataaaaatg agttatcaaa
    68881 attataaatg tgaaagagat tatgtgtatg atgattataa atacaataag tgcaacaagt
    68941 gctataatga ttatgaggaa atgacacatg ttcatgaata ttcagaaagt gttaagttag
    69001 cagaagaatg tgaggataga cataaccacc gtgcagcagg ggttactggt gaagctatac
    69061 caataaatgg aggtacaaat catgttcata aaataaatga taatgtagat ttccttgacc
    69121 atttccataa gatatgtgtt acaacagggc cagcaattag aatacctgga actgataaac
    69181 acattcactt aatatgtgga gaaactactg ttaatgatgg tcattgtcat aaattccttt
    69241 ttactactca aatagaagca cctttagtat aaactgatat ggattattgt agtaaatttg
    69301 ctagattata gtatataata aatgttaaaa atatataata gataatattt aaacttaatt
    69361 aggactatga tacttaacct tcgtagtcct ttctaagttt tgtataaaaa agtgttatac
    69421 aattaaaagt gatataggga ggaaatttta tgaaatctgg aataattctt gaaatgaaac
    69481 aaataaattc aacagaatat gacgaaatgt tgcaagtctg ggaatcatca gtaagagcaa
    69541 cgcatgattt tttaacagaa aaagatattg aatctttgat accattagtt gaaattggac
    69601 ttaaagaagt agaaaatata gtttgtataa aagataatga tataataaag ggctttatag
    69661 gaatagataa agataaaatt gagatgctct ttatagaaga taaatataga ggaaatggta
    69721 ttggtaaaaa attaataaaa tatgctatag ataaatacaa tgtaaaatat gttgatgtaa
    69781 atgagcagaa taaaaaagct gtaggatttt atattcactt aggatttaaa gtgtttgata
    69841 ggtctgaaat agatggacaa ggtaacccat ttccaatact acatatgaaa ttaatttaaa
    69901 gttatacttc tcacttattc gcaaaaatat ttacttaaat ttttatacaa ataaaagtcg
    69961 tgacagtctt aggacacgac ttttttacta cactattaaa ttgaaattta tctgttctat
    70021 attatgatta ttagatgtag tttttttatt tttactatgt acttaaatac caagtatacc
    70081 catacctatc aagtacttca gcagcgccat cattttgatg tggtggtggg tgtggtaaaa
    70141 attcttgtac aagtgtacca ccctcggcaa gttttacaga tatttcttct atcgcttctc
    70201 gagatggtag aacaacacaa atcgccatgc cagaaattac aacaggcttg tctgtatccg
    70261 cacccattat acaaccttcg tattttgtga aagtaacact tgcgtgcata ataggattgt
    70321 ttggattgct gtctaatcgc gcaaatatag tttttcctcc tccgaaagcc tcagcataaa
    70381 aattaaatgc tttttcacaa gtaccattaa atattaaata tggagttagc atgaccaata
    70441 tatcctcctt gatatagaat aatttatagt tgcacctgat aatctaaatt atgatttagt
    70501 aaattgtatc atagggaaac cttgaagtat ataatttttt attattatat tatacaaatt
    70561 tattaattta aaaaaatgtt atatgtacgg aaggtttaca ggataaaata taataaaaag
    70621 attaaggtga cattataaaa aatgtatatt gacattgacg ctacgtaatt gtatatactt
    70681 tgtcttaaag gagatggtaa atatgaatat tatagaaatt cgctcagata aaatatacaa
    70741 gaagataatg gatgcaccaa taaacaaaaa agaagatata tacagatatg aattgatgaa
    70801 gccttttgaa tttaagtgga agtgtatgaa tgttccaata gttgctagac agaaaggtgg
    70861 atatgatgta attatagcaa gtgaaatgtt aggggtttta tcgcctaagg atattgatga
    70921 aaagcaaaaa aagaatataa atgtgttatc tgctgataaa atttggggca cttgcaaaga
    70981 aaccatagaa aactctataa atgcttttat aaaagaaggg tatgatttaa acattaagga
    71041 ctataaatat tcaatattat tggcgaatcc aaatagtcct tatacaatat taagtgatgg
    71101 atactggggt gatggtggga ttcctggata tatatttcta tcattggttc ctaatgaata
    71161 tactatcaat agattaccag tattaatagc acatgaatgt aatcacaata ttagatttca
    71221 gtttatagag tggaataata atataacatt agaagaaatg atgataaatg aaggtcttgc
    71281 agaaaatttt gcaacatgga tgtttggaga ggaaatgtta ggaccttggg tcagtagaac
    71341 agatatcgaa acattaaata cttatataaa gccaataata aaaagtgctt taaaagaaac
    71401 tggatttcaa aatataacat cttatcttta tggtgatgat atagctaaaa tgcaaggata
    71461 ttttccagta gggttgcctt attgtgcagg atatgcttgt ggatattata tgattaagta
    71521 ttatttagaa aagacaaata aatcaataat cgaagcgact ttattgcctt atagtgagat
    71581 aatcgaaaca gtaaaagagt tttgggaata aattttataa attgcataat ttgaaataaa
    71641 ttatgcaatt attttatttt taagaaaaaa taaattgaca ataatttata agaaatatac
    71701 aataatatat ataaagaaat atttcaatat ttaaaagttt taagatttca tatctagagt
    71761 acctaacatt acatgttagt ttcttgttac ttatctaatt actttatatt tcgtagttat
    71821 atataaaatt actataaaaa atgaaatata ttaaacaatc aactaaaaaa tgaaatatta
    71881 ataaaaaaaa ttcaaattat aaatattaaa tgaatataat taaaacaaat atataaattt
    71941 aagtataaca ctcacatttt aatgtattgt gaaatttttg ttgaacttta tgtaccataa
    72001 cttataaaat ttatgtcatg ttatatttga ataagtaata aaattgtaga tgcaaattaa
    72061 tctacaaaat ttatatgaaa tggagttgat gctatgacag aattaatgat tataagtggg
    72121 ttagtactat tgatttgtat aacttctagc aaggtattgt ataaatttgg agtaccaata
    72181 ttattgattt ttatcttact agggatgtta tttgggtctg atggaatggt aggaatctat
//
LOCUS       DAMJWO010000007        61883 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.008, whole genome shotgun sequence.
ACCESSION   DAMJWO010000007 DAMJWO010000000
VERSION     DAMJWO010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 61883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61883
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.008"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(138..1739)
                     /locus_tag="PC366_000546"
     CDS             complement(138..1739)
                     /locus_tag="PC366_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2576097.1"
                     /translation="MIYDLILKNGFIIDGTGNPGFYGDIAIKDNLIAKIDSKINSNTN
                     KEIDCCGKVITPGFIDPHVHEEIVAILDGKFEKFLKQGVTTTINGNCGHSITPYSSEN
                     VYEYMYKNGLLLEEEKKYLIDKNKCWNNFTEYCDLISKSGISVNMGFLLGHGTIRWSV
                     MGGSKDRPPTEKEKNEITDIINDGMKSGAFGISTGLAYIPSKYADIDELVDIARQIKE
                     HDGIYTSHIRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDEILKARYNGVE
                     IMVDTVPRSSGHCMKKKRVIQFIMAISSSLFELGIDGVMDDLRNEEGRTLILKEAFIL
                     GDRGSIILLNTKDINMEKKSIREIATQKGIDEDKLLLDLLLDGDEELIFCLGGMYRAD
                     FPDKLHDNKIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFPIFFNMYRKSGVRLEEI
                     VRRVTSLPARQFKIKNRGIIKEGLIADIAVIDMDNYSYSRSEDIDFSKPQLLANGVEY
                     VIVNGKIALENGEITENKCGEVLKR"
     gene            complement(1850..2527)
                     /locus_tag="PC366_000547"
     CDS             complement(1850..2527)
                     /locus_tag="PC366_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576098.1"
                     /translation="MSKVKSIYNEEYLPFMIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNISILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTILIARAM
                     YKDKLSD"
     gene            complement(2540..3235)
                     /locus_tag="PC366_000548"
     CDS             complement(2540..3235)
                     /locus_tag="PC366_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HDF2576099.1"
                     /translation="MDYLKLANHPLLWIASTVAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCMLEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            complement(3287..4486)
                     /locus_tag="PC366_000549"
     CDS             complement(3287..4486)
                     /locus_tag="PC366_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HDF2576100.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     AKVKSIVDEKIFISLHEHPVLFPEHLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDICRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARNLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSVL
                     AAKFDIKKITGTKEHPKVEYVKGLENPTETSKNIVRYLVKHGYSDEEIEKVLGGNILR
                     VLKQVWK"
     gene            complement(4747..6792)
                     /locus_tag="PC366_000550"
     CDS             complement(4747..6792)
                     /locus_tag="PC366_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2576101.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFCNIDNLVYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNILIVIVHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KVIDINTVIEIFTKLNISIDKLHIIKEKYNEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASVDKLGKFIYCNKVFSNLVGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKNISAIQVLEDKIQNKLQSKGFVSKYTFESVVG
                     ESKIIKEKINIARKIATTDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYDEGSFTGAIKGGKMGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKIIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDIPLISKYFLDEINSNKCFTEESMQALTLYEWPGNVRELKNLIYYIDTIVEEDRVDY
                     EHLPEQFRFEKNNTLVNENFDSIILDFKQSNFFEESICILNSIETWNNKNILLGRNKL
                     QEILKEKDIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYVKIKGVI"
     gene            complement(7203..8012)
                     /locus_tag="PC366_000551"
     CDS             complement(7203..8012)
                     /locus_tag="PC366_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2576102.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTFVGFSMGGAIV
                     LRYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVTD
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFNDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFEYSGHAIFYDELKLFNQEFLQFLEE"
     gene            complement(8096..8629)
                     /locus_tag="PC366_000552"
     CDS             complement(8096..8629)
                     /locus_tag="PC366_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF2576103.1"
                     /translation="MSDAHYDMHKRNGYSSDEPYPEIKVLGLNKYYAELLMDDYAGVS
                     SEFTSVNQYLYHNFDLDETHRELSEMWINISITEMLHMEILAKTIRLLGGNPVYRGST
                     SSCGAYWNGGFVCYGNSICNRLKLDLHLEHVAINNYYKDISLIEDPYIKAILNRIILD
                     EKLHVSLFEKAIEKYCK"
     gene            complement(8756..10831)
                     /locus_tag="PC366_000553"
     CDS             complement(8756..10831)
                     /locus_tag="PC366_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2576104.1"
                     /translation="MLKGLSFRNARRQAGKYLIYWCSLIGSVALIYAFNALIFSDVMQ
                     ELSSILNNGGSDEFSYMIIIFSFIITFILGWFVSYMMNFILKKRSREISTYMILGVDK
                     KQIVKMLFIENLLLGASALIVGWILGIFVSKVLESIVINMFHGKYSLSPDFSLKAAGM
                     TFLYFCIIYLIAQLKSNKKLVKMKLINLLNYDRYNENVLIHQTKTKSIMFCVSVLCGG
                     MGIFFFSIPSGRLTDVFLGLLLIVFCLIVLFMGFGSIAQNMFEKGMNWKYKKSHLFLY
                     RLLASKINGISIIMGIIATLFTVSIACIGIANSFYSVMNKSVDLQQFDVSIFHPNESY
                     DFSSYEGYLSETKGVKKDYSYTLYTEEKTSFMKVRNNILSKYLKDIGRDLQYKDYTFA
                     ENQFDTFMKYSDYNILRNMLGLNPIKMDKNQFIIHCMPYLADAYKNYIGEKYKLTISD
                     KDLSIAGIYIENFSQYGGYGNGQEYIIVIPDYLIDNMKPLYSLYVAITSEPLDSAYFT
                     EFQKKFDTLENLNSGVVVAGNQGFVSKLRYDNKDYISGKYAMQSTGQAIILILPLFYL
                     ALIICIIGTVILSIQLLSENNIIIKHYGMLRTLGMIDSEVIKILKKHVCLYFSIPLIP
                     AVIFGGILVSVFSYNMFNISFDAPVFFNIQIPILHAVAITLINFVVIYCIYVFITYVA
                     LRKEILHIK"
     gene            complement(10834..11580)
                     /locus_tag="PC366_000554"
     CDS             complement(10834..11580)
                     /locus_tag="PC366_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2576105.1"
                     /translation="MLLRVENIEKYYGNQKILTKALNDVSFQINTGEFVSIMGTSGSG
                     KTTLLNCIATIDTVSAGKIYLENQDITELSEENLTVFRRDNLGFVFQDSNLLDTLTLE
                     ENIALPLTIKKVSPVEITNSVYNIATQLKIEEILSKFPYEVSGGQRQRCAVARAVVTE
                     PKLILADEPTGALDSNSSKTLMELLETINTILEATILLVTHDAISASYTERILFLRDG
                     KIFNELRKGEKSRLTFYHEILDALSLMGGD"
     gene            complement(11594..11989)
                     /locus_tag="PC366_000555"
     CDS             complement(11594..11989)
                     /locus_tag="PC366_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HDF2576106.1"
                     /translation="MKKRILTILCVVLVLFISITGLDSMGFFSRSIIPLRSEYASFIR
                     KNGTITEVKFTGPFNHNNIDLNKNVEDTNKNGDDNELTIKYDIEVKKSLISSNEPTIQ
                     IQDSKESIYVYILNFSDKTIIIKNGKIVD"
     gene            complement(12102..13124)
                     /locus_tag="PC366_000556"
     CDS             complement(12102..13124)
                     /locus_tag="PC366_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2576107.1"
                     /translation="MRFCNFLQDKVLVILLNICCAISLVLYLHLIGIGQGELTLLIAA
                     WVAILFCWICFCYQKQKKEIIKLRRIVDELDKKYLFIEMIEKPTSNIEREYYNIIRLS
                     LKSMTDHVSQIHREMYEYRQFIEQWVHEIKHPVTTSELICENYKNEHTRKIRFQMEEI
                     ERHIERALYYARLGHVEKDYLISEITLKSIVEEVLAKNKLLLIQNNIHINIQDLEYSV
                     YTDKKWIVFILNQIIINSVQYKSDSAEISFFAIKEDKSVKFTIKDNGIGIKESEIYRI
                     FELGFTGSNGRTTNNSTGIGLYLCYELSKKMGIDIDVSSSLGEYTAITLNFPINTAIN
                     MQKQCN"
     gene            complement(13121..13792)
                     /locus_tag="PC366_000557"
     CDS             complement(13121..13792)
                     /locus_tag="PC366_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005924879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2576108.1"
                     /translation="MILTNILIIEDDVFICKELMQFFENNGYSTQTLDTNNCDVLQVI
                     QESTPDLILLDINLPNIDGFSLCRQIRNCSTIPIIFITARDSAIDELNGLTMGGDDYI
                     TKPYNLPLLLARVKNLLKRVDSSDKQKIKYREIILNLISATVEYQNAVIELSRTELKI
                     MYYLFQNVGSIVPRIDLVEYLWDNHIHIDDNALSVNITRLREKLRGIGITDLIITKRG
                     MGYRI"
     gene            complement(13878..15227)
                     /locus_tag="PC366_000558"
     CDS             complement(13878..15227)
                     /locus_tag="PC366_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HDF2576109.1"
                     /translation="MELKNFKDILFKKALSEGFEECEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     HYNDVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMLIGFVVPIIEDNGQKYDGIGYNRANSIEEIKPCEISKLGVDNALSKV
                     GGKSIPSGKYKTILLNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIDKGDKSLDEIIKDIDEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEVIGEDLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            complement(15239..16621)
                     /locus_tag="PC366_000559"
     CDS             complement(15239..16621)
                     /locus_tag="PC366_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HDF2576110.1"
                     /translation="MLSKNIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNRDKVSVMKVAYKSAKEFSNDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRIRTRLGISSIASKGNENQTGFEGPGGCKGFEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPTQKNILIENGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDRPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFAVSEG
                     YLIKNGEIQEPVRGASLIGKGSDILMNIDMVGNNVKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            16865..18079
                     /locus_tag="PC366_000560"
     CDS             16865..18079
                     /locus_tag="PC366_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDF2576111.1"
                     /translation="MNQEYVKGNPIFTNINKVPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CTSALEELDTFIKLYGNKCDYAKRDTLLYTANKLEIKAIKEEYNLRKENGFDVEYIDE
                     STNPFSFDLKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNDKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVSFDDIENETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNNNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            18256..20169
                     /locus_tag="PC366_000561"
     CDS             18256..20169
                     /locus_tag="PC366_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2576112.1"
                     /translation="MKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYTNIDVVFGNLK
                     EGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEP
                     FGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAH
                     IVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVD
                     KNFKITLFNKSAEKIFGIKKENALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTK
                     IITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGLSAKYTFDNIIHASEK
                     TKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSL
                     IESEFFGYEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQV
                     MRIGGDKVIPIDVKIICASNKDLKNMMRNGLFRQDLYFRINILTLYLPSLKERKEDII
                     KLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIVESFDSIL
                     LEKVSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRS
                     TLWRKLKEIEDDV"
     gene            20440..21414
                     /locus_tag="PC366_000562"
     CDS             20440..21414
                     /locus_tag="PC366_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HDF2576113.1"
                     /translation="MHILKSVKKIPGGLMVCPLLLGALFNTVCPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGKPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIVALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVVLGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKSIFKTNKNIEVN"
     gene            21435..21710
                     /locus_tag="PC366_000563"
     CDS             21435..21710
                     /locus_tag="PC366_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF2576114.1"
                     /translation="MNAIIHANEKDNLVTCVRPLVKGEKVSIDGKSYIVNDNIPVFHK
                     MATEDVKKGDVVYKYGEIIGIATVDIKTGDYVHVHNIESTRGRGDKK"
     gene            21723..22886
                     /locus_tag="PC366_000564"
     CDS             21723..22886
                     /locus_tag="PC366_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF2576115.1"
                     /translation="MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKK
                     VDYVVIQECGGTLKTVSKGTEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
                     ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKR
                     AIAMGEDLRSGQPTPGNKAGGLSTIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGL
                     YFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF"
     gene            23223..25503
                     /locus_tag="PC366_000565"
                     /pseudo
     CDS             23223..25503
                     /locus_tag="PC366_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439637.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
     gene            complement(25598..26938)
                     /locus_tag="PC366_000566"
     CDS             complement(25598..26938)
                     /locus_tag="PC366_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2576116.1"
                     /translation="MENQEALRHEKIWILLFRYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAEKILGNALTL
                     SIIISLIITILGLVFLEDILFILGASKDSIFYAKDYMSVILIGSIFNLVAFSLNNAIR
                     AEGNPKLAARTMIVGCVLNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVTYYFIR
                     GKSTLKLKKCNLKLNKDIVKKVFAIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKQYERAKKTLILSIIVSVVILSFGFL
                     IVQVFPEVFVGIFNKDSDLMDIAVRGISINLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPVADFIAMIIVLLFLKREFKTSRV"
     gene            complement(26950..27732)
                     /locus_tag="PC366_000567"
     CDS             complement(26950..27732)
                     /locus_tag="PC366_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004460318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2576117.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDMV"
     gene            complement(27747..28769)
                     /locus_tag="PC366_000568"
     CDS             complement(27747..28769)
                     /locus_tag="PC366_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF2576118.1"
                     /translation="MKNIIKINSKTLLVISILMVLIFITFLLSLNMGSFSIEPMDVIK
                     TFLGQGQRNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALIGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSIWGTSWKYVIAVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDVEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            complement(28775..29788)
                     /locus_tag="PC366_000569"
     CDS             complement(28775..29788)
                     /locus_tag="PC366_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF2576119.1"
                     /translation="MTKLSKKNITYLLILVSIVVLVFGIVLSITIGAKDMNLSTVIDS
                     LIKMEDGINMRIVKDVRLPRAIAAALVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFAISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVKWEGIKLLFVAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTNFVRFICIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            complement(29916..30854)
                     /locus_tag="PC366_000570"
     CDS             complement(29916..30854)
                     /locus_tag="PC366_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2576120.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNTEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPVATANVDSYETDKLPSYIREELKGVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSKL
                     FDKEEEAKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLARPKNMPKQDGITLPMVSMEGLTDIDADHIVVIATEADKKDLENSAIWSQIRAV
                     KDGNVTILDAAPFFSQSYNPIGKELLLESVKNELTK"
     gene            31124..31588
                     /locus_tag="PC366_000571"
     CDS             31124..31588
                     /locus_tag="PC366_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576121.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILAGTKTMVIRGAAGRKIPHSRVF
                     EDELLYFMEKGTGKISAKATVKKVENYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITPLDFDHQGNMDDWLIVEKIEDVVVGTSIPYNYEKSKF"
     gene            complement(31700..32017)
                     /locus_tag="PC366_000572"
     CDS             complement(31700..32017)
                     /locus_tag="PC366_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2576122.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
     gene            complement(32030..32761)
                     /gene="chbG"
                     /locus_tag="PC366_000573"
     CDS             complement(32030..32761)
                     /gene="chbG"
                     /locus_tag="PC366_000573"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HDF2576123.1"
                     /translation="MTKIIINADDFGYCEAVNYGIISAHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKTLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDCDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLVSLKPVVEKIVTKYNLPIRGGFEYNLEYSK
                     VVPLIDSFYKENVSEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLEKNGLVISSYRDI"
     gene            complement(32787..34097)
                     /locus_tag="PC366_000574"
     CDS             complement(32787..34097)
                     /locus_tag="PC366_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDF2576124.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEAG
                     KEKLEIVGNLAKRMVKKAGVDMKINLTLDRREALRDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVESDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNNGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLVAKAA
                     VYGDYESALLALCINPLIPSDDLAKTILDEMLEAHKDYLPRFNR"
     gene            complement(34174..35487)
                     /locus_tag="PC366_000575"
     CDS             complement(34174..35487)
                     /locus_tag="PC366_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2576125.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEAYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQSGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMEANKLKINN"
     gene            complement(35509..35820)
                     /locus_tag="PC366_000576"
     CDS             complement(35509..35820)
                     /locus_tag="PC366_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2576126.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKN
                     EIENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSS
                     K"
     gene            complement(36020..36724)
                     /locus_tag="PC366_000577"
     CDS             complement(36020..36724)
                     /locus_tag="PC366_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2576127.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYITRQRGVGSIVIANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADENLSSKLNISLEENVWEIKRVRLANDARVSYMITYMPVKLFPNLNKTHCENSL
                     YNFVEEVCGYKIAMSEREVQAVISNEECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            complement(36819..38180)
                     /locus_tag="PC366_000578"
     CDS             complement(36819..38180)
                     /locus_tag="PC366_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2576128.1"
                     /translation="MKDRINLTEGRITEKLLKLSLPIMGTSFIQMGYNMIDMIWVGKA
                     GSKAVAAVGTAGFFPWLAMAFIMISKVGGEIKVAQSIGANNISTTKSYMKSAIEINII
                     LAIIYTISLIVLNKQLIGFFRLGDLEVITMSRQYLIIVALGMVFYFINPVFTAIFNGL
                     GNSKTPFRINTVGLITNIILDPILIFGWGFAPKLGVAGAAIATVFAQIVVTTCFIYII
                     VKSKEEYFKLRLFKEIETKYYKVLYKLGLPIAIQSGMFTVFSMLLGVIVASWGPVAVA
                     VQKVGSQIEAISWMTAEGLSVALGSFVGQNYGAKKYSRINKGCKIAITVSSVLGIITT
                     LVLVFAGESIFSIFIDESEAIEKGAIYLKILGYSQFFMCLEIITTGAFKGLGRTYIPS
                     IIITILTGARVPLAYFISRPEMLGLNGVWWSITLSSILKGILMISLFISLLKLGKLYK
                     MSE"
     gene            38679..39824
                     /locus_tag="PC366_000579"
     CDS             38679..39824
                     /locus_tag="PC366_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2576129.1"
                     /translation="MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYS
                     LSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAK
                     KTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
                     FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFK
                     RISNPTYTDFANTDYLTGLKNRNAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKF
                     GHQTGDLYIKQASKIIQDVINKKYIVYRIGGDEYIIILKNLSHKEINSIINNINLKIV
                     EENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKKKINK"
     gene            complement(39914..41632)
                     /locus_tag="PC366_000580"
     CDS             complement(39914..41632)
                     /locus_tag="PC366_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HDF2576130.1"
                     /translation="MNNNAISSKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASESLLNSLKNTVFVSVISTVISLTLALVYAYALTR
                     TKIKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGVHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLSSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGVVGIIAFGIIAVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLLTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFNFMDTIYIKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAAALAVLILVTNILVKVIYEFIKNRLE
                     KRTNFN"
     gene            complement(41637..42626)
                     /locus_tag="PC366_000581"
     CDS             complement(41637..42626)
                     /locus_tag="PC366_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2576131.1"
                     /translation="MSYLKINNVFKSYDQKRVLNNISLDIEEGEFLCLLGPSGCGKTT
                     LLRIIAGLEDVNSGTIILQDKDITNLEPSKRGFGIVFQSYALFPNMTAYNNIAFPLKE
                     RKVSKEKIDNKVKEVLETVGLTNEAHKYPKALSGGQQQRIAIARALALEPKFLLLDEP
                     MSALDAKVRHKLRMDIKRLQKELNITTIMVTHDQEEAITMADKIAILNGGDIMQIGTP
                     EEIYQNPQNLFTAQFIGDTNCFDNGDSILTVRPEYVQIEKSTKENYQGIISNIEFRGN
                     LLRVEIKDKLNENFIISDVSIKEWVNLNLVEGDLVKISIDEKYYLKYPKVKGA"
     gene            complement(42722..43771)
                     /locus_tag="PC366_000582"
     CDS             complement(42722..43771)
                     /locus_tag="PC366_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2576132.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADIIWGLSAMNMIELKK
                     DGALEAYKPKNYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGEKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPIEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYAHEVAVTSIKTYNPVPKGYSKQPFEQLIKEVDLNSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            complement(44048..44716)
                     /locus_tag="PC366_000583"
     CDS             complement(44048..44716)
                     /locus_tag="PC366_000583"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HDF2576133.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDTAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSDAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            complement(44722..46095)
                     /locus_tag="PC366_000584"
     CDS             complement(44722..46095)
                     /locus_tag="PC366_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HDF2576134.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            complement(46092..47870)
                     /locus_tag="PC366_000585"
     CDS             complement(46092..47870)
                     /locus_tag="PC366_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HDF2576135.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTTKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            complement(47987..48310)
                     /locus_tag="PC366_000586"
     CDS             complement(47987..48310)
                     /locus_tag="PC366_000586"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HDF2576136.1"
                     /translation="MLMYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVED
                     EYAIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGAD
                     ILFKE"
     gene            complement(48297..49274)
                     /locus_tag="PC366_000587"
     CDS             complement(48297..49274)
                     /locus_tag="PC366_000587"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HDF2576137.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKIMSSAILEAFDVYNKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            complement(49289..49852)
                     /locus_tag="PC366_000588"
     CDS             complement(49289..49852)
                     /locus_tag="PC366_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HDF2576138.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            complement(49904..50395)
                     /locus_tag="PC366_000589"
     CDS             complement(49904..50395)
                     /locus_tag="PC366_000589"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HDF2576139.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            complement(50398..52323)
                     /locus_tag="PC366_000590"
     CDS             complement(50398..52323)
                     /locus_tag="PC366_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HDF2576140.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEGQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPLENMETKYTKTILGTVP
                     ISANIDALRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKDKTEEIKRHADSIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFDCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVVFFGMMLSDAAYGLIIAVVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGILGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            complement(52325..52636)
                     /locus_tag="PC366_000591"
     CDS             complement(52325..52636)
                     /locus_tag="PC366_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576141.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VRKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAEERKSKAIEAVIGKVV
                     R"
     gene            complement(53266..53541)
                     /locus_tag="PC366_000592"
     CDS             complement(53266..53541)
                     /locus_tag="PC366_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif11-like leader peptide family natural product
                     precursor"
                     /protein_id="HDF2576142.1"
                     /translation="MNEKLTKILEEAKNDDEFRKELIKTREQRDVMDSFCKVVTSRGY
                     DITVGELFSMGEEYTSNLLKSVNGGAAYPIEDWSDWYEDFFIMLSNI"
     gene            complement(53656..55065)
                     /locus_tag="PC366_000593"
     CDS             complement(53656..55065)
                     /locus_tag="PC366_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HDF2576143.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGVLFVAYIGMAIFFRNHFYF
                     GTTINGVKASGKTVEQVNDLLTSSTNSYTLNLEERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMITLSYNKDLLEKRFNALSCFDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEAPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     SLSKKYSTFGDSRPFKTATGKDITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNKDDIGNTYVEISLSGQHMWFFKNGEMLVSTDVVTGDLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGGIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            complement(55435..56097)
                     /locus_tag="PC366_000594"
     CDS             complement(55435..56097)
                     /locus_tag="PC366_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576144.1"
                     /translation="MIDVSIDDKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TINQSLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSQESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            complement(56351..58570)
                     /locus_tag="PC366_000595"
     CDS             complement(56351..58570)
                     /locus_tag="PC366_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2576145.1"
                     /translation="MTGRNKSFTLITILFLTSLFLTMGYIYIEDTKHLLMSEAKIHIK
                     EVAVQGSQLAQRQIEKDLDVLNIFSNYYALNQDIPNEEKMKNLLDEMENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYVDEVNKSIKKITISVPLLNNDK
                     VVGVLYCTYNINTLMKLINVSFYENNSISYVVRNDGTIILHPQEDSLSKNIYKLLKQD
                     NDIREINRLKKELQENKTGATVLNMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSEQIINRAIYAVLFIILIFIAIIFYIIYIKKSNEKEILSLAYEDKVTHIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTE
                     GEVYARLSSDYFAIFCDYKNGKNKRIRKIDSIRNNIESNLSIVFEISLCVGIYFVEEG
                     EVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVY
                     YQPKFSLVTGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFERVCND
                     LSEWKKQGKKIVPVSINLSRVELYQPDIVKFINKTIQMYNLSSDLIEIEITETVAINE
                     LNILKNVLNELRKYGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLNGIEHDERSR
                     NIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL"
     gene            complement(58846..61500)
                     /gene="adhE"
                     /locus_tag="PC366_000596"
                     /gene_synonym="adhC"
     CDS             complement(58846..61500)
                     /gene="adhE"
                     /locus_tag="PC366_000596"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDF2576146.1"
                     /translation="MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIREAQKI
                     FATYTQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDESADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDNAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRSPGKVYFKKGCLGVALKELKDVMNKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKHTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     IASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEEPKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
BASE COUNT        20688 a        10762 c         7438 g        22995 t
ORIGIN      
        1 atattatctg attattaaaa taaatattaa tactataaat aaaaacgaag catgattttt
       61 atttaaataa atcccaaact tcgtctttac ttacttagat atttatttac tttctaaatc
      121 ctattatttt taaaacctta tctttttaat acttcaccac atttattctc agtaatctct
      181 ccattttcta acgcaatttt tccatttaca attacatatt caacaccatt ggctagtaat
      241 tgtggctttg aaaaatcaat atcttctgac ctagaataac tatagttatc catgtcaata
      301 actgctatat cagctatcaa cccttcttta ataatacctc tattttttat tttaaattgc
      361 ctagctggta atgaagtaac tcttcttaca atctcttcca atctaacacc agactttctg
      421 tacatattga agaaaattgg aaaagctcct cttctttgta gttcaaacca tgacatatcc
      481 ccacccacac taaacaaaca atctgaacca accataacaa atggattatc aattatttta
      541 ttatcatgta gtttatctgg gaaatcagct ctatacattc ctcctaaaca aaagataagt
      601 tcttcgtctc catctaaaag taaatcgagt aataacttgt cctcatctat tcctttttgt
      661 gtagctattt cacgtattga tttcttttcc atattaatat ctttagtgtt tagaagtatt
      721 atactccccc tatctccaag tataaatgct tcttttaata taagtgttct tccctcttca
      781 tttctaagat catccattac cccatctata cctaattcaa atagactaga tgatattgcc
      841 ataataaatt gaattactct ttttttcttc atacaatgcc cagaacttct tggtactgtg
      901 tcaaccatta tttcaacacc attataccta gcctttaata tctcatcaaa tgcttctatt
      961 tcaactggac ttaagtgaga tacttgaacc ctagcaccac ttttttgccc aacctctatg
     1021 gcttctttta ctgcattata tcttcctatg taatctctaa tatgagatgt atatatacca
     1081 tcatgctctt taatctgcct tgcaatatca acaagttcat caatatcagc atacttactt
     1141 ggtatatatg ccaatccagt agatattcca aaagcaccac ttttcattcc atcatttatt
     1201 atatctgtaa tttcattttt ttccttttct gtaggaggtc tatccttaga acctcccata
     1261 acactccatc ttatagtccc atgccccaac aagaatccca tattgacaga aataccactt
     1321 ttagatataa ggtcacaata ttctgtaaaa ttattccaac atttattttt atctataaga
     1381 tacttttttt cttcttcaag taatagacca tttttataca tatattcata tacattttca
     1441 gaagaatatg gtgttataga atgtccacaa ttaccattta tagttgttgt aactccttgt
     1501 tttagaaact tttcaaattt accatctagt attgctacta tttcttcatg aacatgaggg
     1561 tcaataaatc caggtgttat aacttttcca caacaatcaa tctctttatt tgtattgcta
     1621 tttatcttag aatctatttt tgctattaag ttgtctttaa ttgctatatc tccataaaaa
     1681 ccaggattac ctgtaccatc tattataaat ccatttttta agattaaatc atatatcaaa
     1741 atattccctc cttaaaaacc aatttttaaa taatcttaat gtaattttta tatttgaaaa
     1801 tcaaattatt atatttcata tttgaaaatt cactattatt tcattgtaat tagtcactaa
     1861 gcttatcttt atacatagct cttgcaatta atatagtacc aaatacacat ataagaacta
     1921 ctagagactg tggtattata ccttgctttg ataatataat agtcaataca gatattacaa
     1981 ttgctactag acctaatttt ttatcttgta aaaatacttg tccaaaaact gacccaaata
     2041 gagctggtaa aattaagttt aatttttcta ctacttcagc tggaatttta gataatacgc
     2101 ttcctcctaa aattacccct atagttagta tacttatatt cactaaaata gatacagcta
     2161 ttcctattgt agatattatc gagccttctt ctgtacctga ttcaacttct gctgcctttt
     2221 gagctgctat tgaacatggt agcctcatat tagatatatt accagaaaga aaactcatat
     2281 aagttcctgg gatacctaag attggtgaat aagaaactgg ttctattatg taatttggag
     2341 cactcatact gacaattgcc attgtacttg ctaataatgc tgatattgga ggcataatac
     2401 caaatccaaa gctcaaaatt attccaggaa ctaatgctgc tataatacct aaagatagtg
     2461 ttagtcttcc ataccttatc ataaaaggta aatattcttc attgtatata gattttactt
     2521 tactcataaa actcccccct tatattactg aagctattat cattccgcta aacattgata
     2581 ttgtaagccc ccactctctt aaccatttta tatttttctt cttttcaagc atacacaata
     2641 ttaccattat agccattcca cttatacatg caattgttcc attatcaaaa cgcaacaccc
     2701 tatcagcatt tagatatgca aatgaaccca acattgctcc tagagatatt attggtataa
     2761 atgatttctt gccactagat ataacattgg ttatcttatc tagtttatgt ccaaatagta
     2821 atgtgaatat tatccatcct aaagaaccta atatcatagt ccaaactgca tttgtaaatg
     2881 caagttttgt catttcagga gaacctaaag ttatacctaa tgcatctgtt ccaaatccag
     2941 ctgacattga ttcaaaaatt acagaaccta taaatgataa tctcatccat gctataggcc
     3001 cacccatagt tactataagc gataccattc cagcaaatat agtcattgaa ggcccaatag
     3061 ctgaaatagc actactctta acagctgact ttatttgttt atctgttatt cccattgttt
     3121 taccaacttt gcaagatttt atagcaaata taagggattg taccactact attgatactg
     3181 ctactgtact cgctatccac aaaagtggat gattagctaa ttttaaataa tccatttata
     3241 aaacctccct ataaatcctc aaattttatt aatatttcta atatatctat ttccaaacct
     3301 gttttagtac tctaagtata tttccaccta gtaccttctc tatttcctca tcactatatc
     3361 catgctttac taaatatctg acaatgtttt ttgaagtttc tgttgggttc tcaagacctt
     3421 ttacatattc tactttggga tgttcttttg tacctgttat tttttttata tcaaatttag
     3481 cagctagtac tgagtgtaat tttacatggt cgccatatac tgtatctggt ccaaaagcta
     3541 catggtctat tcctactaaa tttttaatat actcaaaatg ttccataaat gactctattg
     3601 aatgttcttt attcttctct gttattgtag tatgaggtgc tgcttctaca cctataaccc
     3661 ctcctttttt agcacatgct attaatactt catctggagt tagtctcttt gtgttccata
     3721 aatttcttgc cccaacatgg cttaatatta ttgggtcctt gctatattct attacatcaa
     3781 gtgtagtttg aactccaacg tgagagcaat ctattgccat tccaatttta ttcattcttt
     3841 caacagcttt ttttccgaaa tttgtaagac ctccatcttt ctcttctttt agtcctgaac
     3901 ctaatgcatt ggattcgctg tatgttatac ccattaacct tataccaaat ccatacagta
     3961 tatctattct atcaagttca ttttctattg gtgctgcacc ttctaatgtt ggtatcaatg
     4021 ctactttacc ttcactttta gctctgcata tatcttctac tttttcacac tttatgacaa
     4081 aatcttgatg agctaaatca catagtctca tgcctaaatc tattaatata tcatcccatt
     4141 tccaccctga atttgatgtt atcgtacata caccatccat taaattatca aatatagcat
     4201 cataatatcc tcttgataat gcttcataag cgcatctttg tttaccttcc ctattatatt
     4261 caaatatatc tctttctagg tgttctggaa ataatactgg atgttcatgt aatgatataa
     4321 atattttttc atccactata cttttaacct tagcttcttg aatatcatct aattcaataa
     4381 ggtactcttt aactctttta tctcctttac acatctcaat agatgaaata tcttttcctt
     4441 tttctaaata actataggct tcatatcctt tgtaagctga cttcataaca acatcctcca
     4501 agttctacaa ttttttatat ttttcctatg tagcaattga tatgccaaaa tataaatttt
     4561 aattgtataa taaatcttgc aaaaaataaa aacagtagta aggttgatat ttactactgt
     4621 tttattaaaa ataatcttct tagattattt attcaatatt tttgaattat cttaatctta
     4681 aagataattt tatttatttc tatccattat agggattttt ttagggtgtt ttgccttttt
     4741 agtcccctat atcactccct taatttttac atatgatata aagttctttc cttcatcagt
     4801 tataaaacta ccttgttttt ttactccaga taaaagtaaa ccatggctct ttaacttatc
     4861 tattcttttt ctaatttggt ctacacttaa aactatatct ttttctttta aaatctcttg
     4921 cagtttattt cttcctaata atatattttt attattccaa gtttctatac tgttcaatat
     4981 acatatactt tcctcaaaga aattagattg tttgaaatct aagataattg aatcgaaatt
     5041 ttcattaact aaagtattgt ttttttcaaa tctaaattgt tctggcaaat gctcgtaatc
     5101 tactctatct tcctcaacta tagtatcaat ataataaatt aaatttttaa gctctcttac
     5161 atttcctggc cattcataca atgttaaagc ttgcattgat tcctctgtaa aacatttgtt
     5221 gctatttatt tcatctaaaa aatacttact tataagaggt atatcttcct tacgttctct
     5281 aagtctaggt atctctatat gtaatacatt aatcctataa tacaaatctt ctctaaaaga
     5341 accttcttta atttttttct ttaaatcttt atttgttgca gctataattc taacatctat
     5401 tggtataatt ttacttccgc ccattctcat aacttctttt tcctgtaata ctcttagcaa
     5461 tctctgctgt acatctaaag atatatcacc tatctcatct aaaaaaattg ttcctgtatg
     5521 cgctctttca aatataccca tttttccacc ttttattgct cctgtaaaac ttccttcatc
     5581 atagccaaaa agttcacttt caataagtgt atctgacaaa gaagatagat taactgcaac
     5641 aaatggcttg ttttttctta gagattcatt atgtattgcc tgggcaaata tttcttttcc
     5701 tgttccattt tctccaagta tcaacacaga aaagtctgta gttgctattt ttcttgcaat
     5761 attaattttt tcttttatta ttttactctc acctacaaca ctctcaaatg tatactttga
     5821 tacaaaacct tttgactgaa gtttattttg aatcttgtcc tcaagcactt gaattgcact
     5881 tatattttta atgcttataa tactctttat tcgttcatta ttttcataaa catttacttt
     5941 attaattatc agttttttgt tatttaaatt tactacttca tcattaactt catcttcttg
     6001 aaaaaatatt tttttgacaa ccttatcact aaataagtcc ataaagttat tagatataat
     6061 ttcattttgg tctattccaa ctagattaga aaatactttg ttgcaatata taaattttcc
     6121 taatttatca acagaggcaa taccttcatc tataatctcc aaaaaactct tcatggtttt
     6181 attcatagtt gtataatacc tatatccact tactgtatct tcattgtatt tttccttaat
     6241 aatatgtaat ttatctatag atatatttag ttttgtaaag atttctataa ctgtatttat
     6301 atcaattacc ttatcaccta tgtcaattat ttgctttatg ttttgtggta tgctgtttct
     6361 gcttcccgta ataattccaa tctcacattt agacttatca caacctggat aatatggtat
     6421 tagattaata tgaattaatc ctagttttct aattatcttg gcagtttcat ctgctgactc
     6481 tttataagca tctataacca taacatcaga atcattttct atacttatta tctgatttat
     6541 attttcaata tttatagtac gatgtactat tacaataagt atatttttat caatattatt
     6601 atgtatatat tcctttatat cattgtctga acatactaca agctcatagc ttgacagttc
     6661 aatatttatc ctatttacat ataccaagtt atctatatta caaaattctc caaatatatt
     6721 ttccaattgt tttgatatat ctatatttat tttgtcatca gttgatacaa ataaaatatt
     6781 atgttttttc atagtcccac ctcctgttta acgagtatag aaagtaataa tttggtctat
     6841 tgtagcactt tttaaaaaag ttttaaatct taaaaatcaa attttgtacc atttactatt
     6901 attttccata ataaaataat gtaagctatc ttttttcaca tataatttaa tttctaaaac
     6961 ggttagtttg acattattgg aatataaaca aaaatttaat ataaattcgt taatatatta
     7021 atacattttt aagaatgaca aggaataaat tataacaaat tttaggaata tataataata
     7081 gggtctcaga acttagttac aagttctaaa accctatttg tttagtgtaa aaaacatcat
     7141 aaaatttagc ttaaatcttt tcacataata ttactctttt tctaagtgat aataaaatat
     7201 atctattcct ctaaaaactg taaaaattcc tgattaaata gtttaagctc atcatagaat
     7261 atagcatgac cactatactc aaaagtatat aaaattgaat cttctatttt ttcattcata
     7321 aaaactgcaa attcatacgg acatatttca tctaatttcc catgaaatat accagtaggc
     7381 actcttacac attttaaatc attaaataat tcttcatctc ttaaagatac agcagttcca
     7441 atagtgccaa tacctgatgc actaaaacca atatcattaa accatcttct aaagctttct
     7501 ggtggatttg atgcaaatac tttttctcca aaatcggtta ccatttctgg tctatcagta
     7561 catgcttgtg ctatcaattt atttacatct tcacgtgtca taccatatgg aaattctgga
     7621 ggtctttgta caaatgatgg tgcagcagct gcagctaata ccaattttga cactccatat
     7681 ccattaaata aactcatata cctaagtacg attgctcctc ccattgaaaa accaacaaag
     7741 gtaaagtctt ttaatccaat agcatgtacc accttataaa tatcgtctgc taattggcta
     7801 taagtatatc ctcctgatgt tgcatcagat ttaccaaaac ctcttaaatc aattgaaact
     7861 gttctatatc cgagttttgg caatatattt gtttgatatt caaatatctt atgtcctaag
     7921 ggccaaccat gtataaaaag tacagttttt ttagcactcg gattcaaatc atatactgct
     7981 atgtttatat cattcacata tacataatac atatcaacag caactccctt caagaaaatg
     8041 tatgatggtt attttatata tatgaataaa atgatgaata actaaatttt taaatttatt
     8101 tacaatactt ctctattgcc ttttcaaata aacttacatg aagtttttca tctaggatta
     8161 ttctatttaa tatagctttt atataagggt cttcaataag acttatatct ttataataat
     8221 tattaatagc cacatgctcc aaatgcaaat ctagttttaa tctgttacaa atagaatttc
     8281 cataacatac aaaaccacca ttccaatatg caccacaaga acttgtagaa cctctatata
     8341 caggatttcc acccaataat cttatagtct ttgctaatat ctccatatgt aacatttctg
     8401 ttatagatat atttatccac atttcactta actctctatg cgtttcatct aaatcaaaat
     8461 tatggtatag atattgattt acactcgtaa attcacttga tactccggca tagtcatcca
     8521 tcaataattc tgcataatac ttatttagac ctaaaacttt tatctctgga tatggctcat
     8581 cacttgaata tccatttcgc ttgtgcatgt cgtaatgtgc atcactcata atatctcctc
     8641 ctttaaattt aatacttgat attaattgta tgcatcacga ctttttcata taacttagat
     8701 aataaaatct attatattat tttctattat aatttatgtg tcaattcacc caaatttatt
     8761 tgatatgcaa tatttctttc cttagtgcta catatgtaat aaaaacatat atacaatata
     8821 ttactacaaa attaataagc gtaatggcta cagcatgtaa gataggaatc tgaatattaa
     8881 aaaatactgg agcatcaaaa gaaatattaa acatgttgta tgaaaaaact gataccaata
     8941 ttccaccaaa tattactgca ggaattaatg gaatcgaaaa atataaacaa acatgtttct
     9001 ttaagatttt tattacttca ctatcaatca tccccaaagt tcgaagcatt ccatagtgtt
     9061 ttatgataat gttattttcg ctcaataatt gaatagagag aatgactgta ccaataatgc
     9121 atataatgag tgccaaataa aaaagtggta atatcaagat aatggcttga ccagtagatt
     9181 gcatagcata ctttccactt atataatcct tattatcata tcgtaattta gaaacaaagc
     9241 cttgattacc tgctactact actccagaat taagattttc taaagtatca aactttttct
     9301 gaaactcagt aaaataagca ctatccaaag gctcacttgt aatagcaaca taaagactat
     9361 acagaggttt catattatca attaaataat ctggaatgac aataatatat tcttgtccat
     9421 ttccatatcc tccatactgt gaaaagttct ctatataaat acctgcaata cttaagtcct
     9481 tatctgatat tgtcagttta tatttttctc caatataatt cttatatgca tcagcaagat
     9541 aaggcataca atggatgata aattgatttt tgtccatctt tattgggttt aaacccaaca
     9601 tatttcttag tatattgtaa tcactatatt tcataaatgt gtcaaactgg ttttctgcaa
     9661 aagtataatc cttatattgt aaatctcgcc ctatatcttt caagtattta gaaaggatat
     9721 tattacgaac cttcataaag gatgtttttt cttctgtgta aagagtataa gaataatcct
     9781 ttttcacacc tttcgtttct gataaatatc cttcatatga agaaaaatca tatgattcat
     9841 tcgggtgaaa aatactcaca tcaaattgtt gtaaatccac tgatttattc atcacagaat
     9901 aaaatgagtt agctattcca atacaagcaa ttgatactgt aaaaagagtt gcgataatac
     9961 ccattataat gcttattcca tttatctttg aagccagtag acgatacaaa aataagtgag
    10021 atttcttata tttccaattc atcccttttt caaacatatt ctgtgcaata gatccaaatc
    10081 ccataaataa tacgattaga caaaatacaa tcaacaataa accaagaaat acatctgtta
    10141 atctaccact aggtattgaa aagaaaaaaa tacccatacc tccacacaaa acagacacac
    10201 aaaacataat agacttcgtt tttgtttggt gaattaatac attttcatta tatcgatcat
    10261 aattaagcaa attaattaat ttcattttaa caagtttttt attacttttt aattgagcaa
    10321 ttaaatatat tatgcagaag tataaaaaag tcatcccagc agcttttaat gaaaaatccg
    10381 gagataaaga atactttcca tgaaacatat taataacaat agattccaaa accttagaaa
    10441 caaatatccc tagaatccat ccaacaataa gagcagaagc acctaataaa agattctcta
    10501 taaaaagcat tttaacaatt tgttttttat ctactcctaa tatcatataa gtacttattt
    10561 ctctgcttct ttttttcaat ataaaattca tcatataact aacaaaccag cctaaaataa
    10621 aagtaataat gaacgaaaat atgataatca tataagaaaa ctcatcgctt cctccattat
    10681 taagtatact agaaagttct tgcattacgt cggaaaatat caaagcgtta aaagcataaa
    10741 tcaaagctac agagcctatt aaggaacacc aataaataag gtactttcct gcttgtcgtc
    10801 ttgcattacg aaaagataat cctttcaaca taatcaatct cctcccatca aagaaagtgc
    10861 atccaaaatt tcgtgataga aagtaagtct ggatttttct ccttttctaa gttcgttaaa
    10921 aattttccca tcccttagaa ataaaattct ctcagtataa ctagctgaaa tagcgtcgtg
    10981 tgtgacaaga agaatcgtag cctctaatat ggtgtttata gtttccaaaa gttccattaa
    11041 agttttagat gaattagaat ccaatgcacc agttggttca tctgccaaaa taagtttggg
    11101 ctctgttaca actgcacgag ctactgcaca acgttgcctc tgaccaccag atacttcata
    11161 aggaaacttc gaaagtatct cttcaatttt caattgtgtg gcaatattat acacactatt
    11221 agtaatttca acaggagaaa ctttttttat tgtaagtgga agtgctatat tttcttctaa
    11281 tgtcagagta tctaataaat tagaatcctg aaaaacaaaa cctaaattat cacgacgaaa
    11341 aacagttaag ttttcttcgg atagttcagt aatatcttga ttttcaagat aaatttttcc
    11401 agcacttact gtatcaattg tagcaataca atttaacaaa gtagttttac cagagccaga
    11461 agttcccata atactgacaa actctcctgt attaatttga aatgacacat cattcaaggc
    11521 ctttgtaagt attttctgat tgccataata tttctcaatg ttctctactc gtaatagcat
    11581 gttaaagtcc tccttagtca acaatttttc catttttaat tattattgtc ttatctgaaa
    11641 aattcaagat atatacatat atgctttctt tagagtcttg aatttgaata gtaggttcat
    11701 tagatgaaat tagagatttt tttacttcaa tatcgtattt tattgttaat tcattatcat
    11761 ctccattttt attagtatct tctacatttt tatttaaatc aatgttatta tgattaaagg
    11821 gaccagtaaa ctttacttct gtaatagttc cattttttct aataaaagaa gcatattcag
    11881 accttagtgg tatgatactt cgtgagaaaa aacccatcga atccaatcct gtaattgaaa
    11941 taaacaaaac gagtacaaca cataatatag ttaatatcct ttttttcata tgtttctccc
    12001 tcctttctat tgatattgta gcgtaaatag taatctgaat atatagaagt tacttaactt
    12061 tatcttacag ttttgaaaga taaagaaata gcagcgcatt tttagttgca ctgcttctgc
    12121 atattgatag ctgtatttat tgggaaattc aatgttattg ctgtgtattc accaaggctg
    12181 gaggacacat ctatatcaat tcccattttc ttagacagtt cataacaaag gtaaagacca
    12241 atccctgtag aattgtttgt agtccttcca ttactgccag taaaacctaa ttcaaaaatt
    12301 cgataaattt cactttcttt gatgccaata ccattatctt ttatagtaaa cttaacactc
    12361 ttgtcttctt ttattgcaaa aaatgaaatt tcagctgaat cacttttgta ctgaacacta
    12421 ttgataataa tttgatttaa aataaaaact atccactttt tatcagtata tacactatac
    12481 tccaaatcct gtatattaat atgaatatta ttttgtataa gaagcaattt attctttgct
    12541 aatacttctt ctacaattga ctttaatgtt atttcagaaa ttaaataatc tttttcaaca
    12601 tggccaaggc gagcatagta caatgcacgc tcaatatgac gttctatttc ttccatttga
    12661 aaacgaattt ttcgtgtatg ttcattttta taattttcac atataagttc tgatgttgta
    12721 acaggatgtt ttatctcatg tacccattgt tcaatgaatt gtctatattc gtacatttca
    12781 cgatgtattt gagaaacatg atctgtcata gatttcaatg ataatctaat aatattgtag
    12841 tattcacgtt ctatgttaga agtaggtttt tcaatcattt caataaacag atatttttta
    12901 tccaattcgt ctacaatgcg acgtaactta ataatttctt ttttctgttt ttgataacaa
    12961 aaacatatcc aacaaaataa aattgcgacc caagcggcta taagaagagt caactctcct
    13021 tgaccaatcc ctataagatg aagatatagc actaatgaaa ttgcacaaca aatatttaag
    13081 agtataacta atactttatc ttgaagaaaa ttacaaaacc tcatatccta tatcccatcc
    13141 cccgttttgt aatgattaag tcagtaatac ctatacccct taacttttct ctaagccttg
    13201 taatgtttac acttaaagca ttatcatcaa tatgaatatg attgtcccat aaatattcta
    13261 ccaaatctat acgaggcaca atactcccta cattctgaaa caaataatac atgattttta
    13321 gttcagttct tgaaagttct ataacagcat tttggtattc tactgtagct gaaataaggt
    13381 tgagtataat ctctctatat ttaattttct gtttatctga tgaatctact cttttaagta
    13441 ggttctttac ccttgctaaa agcaaaggta agttatatgg ttttgtaata tagtcatctc
    13501 cccccatagt caaaccattt agttcatcaa ttgcactatc tcttgctgta ataaaaataa
    13561 taggtatagt agaacaattc ctaatctgtc tacataaaga aaaaccatct atattaggca
    13621 aattgatatc caagagaatt aagtcaggtg ttgattcttg gattacttga agtacatcac
    13681 aattatttgt atccaatgtt tgtgtactat agccattatt ttcaaagaat tgcattaatt
    13741 ccttacagat gaacacatca tcttcaatta tcaaaatatt ggttaaaata ataaatacct
    13801 catttcttta gtttatattg ctttaatttt gtaagtaata tatttttcca tatattactt
    13861 acaaaattac tttttaatta ttcatctttt ccagctactg atagctcttt aataacaact
    13921 gaaggtgaac ctatactact cattggaaat tctaaatctt cccctataac ttcaatatct
    13981 ttcaacaggt caaaatagtt tcctgctact gtaatttgct ccactggaaa tacttttttt
    14041 ccttctttga tataaaagcc tttggcagct aaagaaaagt ctcctgttac tgaatttgca
    14101 cctgaatgaa gccctgcaaa gctagtaacc atcaatcctt catctatatc ctttataatt
    14161 tcatctaaag atttatctcc tttatctata taaaaattag ttggatatat gcttataggt
    14221 gatgaatatg aagattttat tccatttcct gtagtcttta cacctgcctt attagccgtt
    14281 tttaagttat gaagtaaagt tataagcttt ccatttaaaa caacttcttt tttaaatgta
    14341 gctactcctt catcatcaaa aggagtagat gccataccat tttctaaaag tgggtcatca
    14401 actattgtaa ctataggaga tgctatcatg tctccttctc tatttttcaa taaagataat
    14461 cctttttgag ctgaatctgc attaaatatc ccagaaaatg tgctaagcaa agataccata
    14521 gcttcattaa gcaatatagt tttatattta cctgatggaa tactcttacc acctacttta
    14581 gataaagcat tatcaacacc aagttttgat atctcacaag gttttatttc ttcaatagaa
    14641 tttgctctat tatatcctat tccatcatat ttttgtccat tgtcttctat gataggaact
    14701 acaaacccta taagcatatt agttttattg cttaaattaa gacctttagt attagatata
    14761 ccattacttg atacagaata agatatagta catttagata aatttaccac cttatctgaa
    14821 taagctttag tctctctttc catttctaaa gctaaatcaa tcaacttatc tgcctctaaa
    14881 ttttctagct ctttagaata agtctttaca tcattatagt gcttatctcc ttcatatata
    14941 aattgtacat cttcattttc aatagtgttt actccatctt ttacattttt tatcaacata
    15001 tcaacagctt tatcatctaa aatttctgta taagaataac ctatctttcc atttacctta
    15061 cctctaaaag ataaaccaaa agatttatca agattgtatt tctcaacttc tccttcatat
    15121 atatttatac ttaaattttc tcctgtataa taatatattt cacactcttc aaaaccttca
    15181 cttagagcct ttttaaataa tatatcttta aaatttttaa gttccacaat tatccctcct
    15241 atcttccacc tacagtaatt tcttttaccc ttatcatagg ttggcctaca ttagttggta
    15301 tacttcctga tgatgagcca cacatcccct gagcttgttt tacgttattc ccaaccatat
    15361 ctatattcat aagtatatcg ctaccttttc caattaaact agcacctctc actggctctt
    15421 gtatttctcc attttttatt aagtaacctt ctgaaactgc aaaattaaac tctcctgtta
    15481 caggatttac agaaccacca cccatttttt tagcataaag tccatctggt attgacttta
    15541 taatgtcttc tggtctatct tctccagcag caatataagt gttagtcatc cttgaagttg
    15601 gtgcaaattt gtagttctgt ctacgagaac ttcctgtagg attcattccc attcgtctac
    15661 cattaagttt atctatcata taagacttca aaattccatt ttcaatcagt atattctttt
    15721 gagttggatt tccttcatca tctatattca tagaacccca gtagtttggt attgtaccat
    15781 catctatagc tgtaatcttt gtggaagcaa tctgttgacc taatttatct gcaaatacag
    15841 agttcccctt tgcaactgat gtagcttcca aagaatgtcc acaagcttca tgaaatatta
    15901 ctccaccaaa tccattatct attgctacca tcatattacc tgcaggacaa tttttagcat
    15961 gcaacatagt atgcgctact ctagctgatt cttttgcata atattctggg tctatttctt
    16021 caaatatttc aaacccttta caacctccag gaccttcaaa tccagtttga ttttcattac
    16081 ccttagatgc aattgaactt atccctagtc tggttcttat tcttctatcc tcaacatata
    16141 taccttcagt gtttgcaatt aatatttttt ggtctttatc caaatagcta acacttactt
    16201 gagatatatc attactaaat tcttttgcac tcttatatgc aaccttcata acacttactt
    16261 tatctctatt tcctattgaa tttggataaa tttttatatt atgtatgtta tttattttaa
    16321 tactgtcatt taatattaca ctttttccat cttccaattt acctaaagca acagcagctt
    16381 tgtatgctac atccaacaga ctatttaatg aattgtcact tgtataagca tatatactct
    16441 tcaatccttt aaatattctt attcctatac cataatttct tccacctatt gcattttcta
    16501 ctttattatc aattaaacta atagaattat ttatagtgtc ttcttcaaaa atctcagcaa
    16561 aatctcctcc agtaattaga cacttttcta ataccttaga agctatattt tttgaaagca
    16621 taaatttacc tcctacttta aatttttaat taacttttat tcaatctttt tacttgttaa
    16681 caaacattat atactatatt acttaaaata aggtaattat gaatatatta tacatatgtt
    16741 ttatactaaa atgttatcac attttatcta tacataccca tataactaga taattaaaat
    16801 gtataatatt atttgctata gaaaataata cactcataca taataaattt taggagtgaa
    16861 gtatatgaat caagaatatg taaaaggaaa tcctattttt actaatatta ataaagttcc
    16921 aagacaattt ccatacctta ctgatgatat tgatactgat gttataattg ttggtggtgg
    16981 cgtaactgga tgtatttgtg cttactatct agctaaaaac aatataaagt ctgtcattct
    17041 tgaaaaagga aggattgcac atggaagcac tagcgtgaca acttctctat tacagtatga
    17101 attagatgac aatttgatag atttaacaga ggttatgact ctaaaagatg ctctaaaagc
    17161 atataacctt tgtacttcag cacttgaaga attagataca tttataaagc tatatggaaa
    17221 taagtgtgat tatgccaaaa gagatactct actttatact gccaacaaac ttgaaattaa
    17281 ggctatcaaa gaagaatata acttaagaaa agaaaatgga tttgatgttg aatatattga
    17341 tgaatccaca aaccctttta gctttgattt aaaatcagga ttgatagcaa agaatggagg
    17401 acgagaatta gacccatata aatatagtca ccatttgatt gatgtaagtt taaaaaatgg
    17461 tcttcaagta tatgaaaata cagaagtaaa aaaagtagat ttatcaaatg ataaggttac
    17521 tgctgaagta tcgtatggat acaaagttca tggtaaaaaa ttaattgtag ctacagggta
    17581 caatacaagt ttatttacaa aaagaaattt tgcaactaag tcaaatactt ttaatatagc
    17641 aactaaacca cttaaaaaca tagcttcttg gaaaaacaac attttaatta gagataactg
    17701 tgacccatat aattatctaa gaactactaa agacaatcga ttaattatag gtggtgaaga
    17761 tgtaagtttt gatgatatag aaaatgaaac tttagccaat gaaaagtatg atattttaga
    17821 acaaagattg aaaagtatgt ttaaggatat aaaagacatt gaagttgaat ataaatattg
    17881 tggttgtttt gcttcaactt tagataattt aggttttatt ggtccagata ataaaaataa
    17941 caatctatgg tattgcttag gttatggagc aaatggtata ctctttgcaa tattaggagg
    18001 tataatgtta agtgaattat atcttggcaa acaaaataaa aatatgaaat tatttaaagt
    18061 agatagattt gataaataga tattgtatat taaaagacta taaaaagatg aaactttata
    18121 attctaaaag ttaactttga tacagtcttt tataatgttc cttttaaaaa tactttattt
    18181 ataattaaat ataaagtaaa atgttaaaat ataactgata aaatttagtc ataagataat
    18241 atttaagttt atttgatgaa atatggagga attattatga aagaaatact cgttattgct
    18301 cccactaaag gaacctatga aaaatcaatt cacatagtta aaaaaaacaa atatacaaat
    18361 attgatgttg tatttggcaa tctaaaagaa ggtatacctc ttgctgaaaa aagtattaat
    18421 catggtacta gaattatcat aagcagaggt ggaacttaca atatgttaaa agctacttac
    18481 aatataccta tagttgaaat taaagtagat gcttatgata ttataaaaag ttacaaagag
    18541 gtaaaaaatt ccaacgaacc atttggaata attggattta ataatgtcat ctacggtttc
    18601 gatattatag aagaaatatt gaataagaaa ataactatga ttgaaattga aaaagaagaa
    18661 gaaatttatg atgctataga aaagtacaga aagaaaggta taaacacata tataggagat
    18721 accactgttg cacatattgt taagagactt aattgtaagg gaatattaat cgaatctaga
    18781 gaagaaaaca tacttagagc cattcaacaa gcagaacaaa tactcgaagc aaccaaggat
    18841 gaacaaaaaa gaagattaca gatagaagct atgacagatt ttgtacatga tggaataata
    18901 acagttgata aaaattttaa aataacatta tttaataaga gtgctgaaaa aatatttggt
    18961 ataaaaaaag aaaatgcact ttatcataat gttgtagatg ttatcccaaa cacagttctt
    19021 ccacaagtag ttgagactat ggaacctcaa attggtgaaa tacaaaatat agggagtaca
    19081 aaaattatta caaatagagt tccaataatt gttgatggcc agattcaagg ggctgtttca
    19141 acatttcaag atagcaagga gataagttct tttgaacata caataagaag gagcttatta
    19201 agcaaaggtc tatctgctaa atacactttt gataatataa ttcatgctag tgaaaagaca
    19261 aaagattgta tagaacttgc aaaaaaatat gcttgttatg atactcctat gattattact
    19321 ggagaatctg gagttggtaa agaattattt tgtcaaagta tacataacta tagtaagcgt
    19381 aaaaatgcac cttttgttgc tgtaaattgt gctgccatac ctccatctct aatagagagt
    19441 gagttttttg gttatgagga aggttcattt acaggtgcta gaaaaaaagg taaagcaggt
    19501 gtattcgaac tagcacatga aggtacaatc ttcctagacg aaataagtga aatccctctt
    19561 gaacttcaag gtcgattatt gagggtattg caggaaaaac aagttatgag aattggtggt
    19621 gataaagtta ttcctataga tgtaaaaatt atctgtgctt caaataaaga cttaaaaaat
    19681 atgatgcgca atggtttatt tagacaagac ctttatttta gaataaatat actaacatta
    19741 tatcttcctt cattaaaaga aagaaaagaa gatattataa aattatcaga attttttata
    19801 cataaatatt caagcaaata caataaaacg cctttaatta tcactccaaa tattaaaaag
    19861 gcacttcttg aacgagaata tgaaggtaat ataagggaat tggaaggtat gatggaaagg
    19921 gctgttattg tggaatcatt tgactcgatt ttattagaaa aggttagcaa tgaatataca
    19981 aataatatag ttgataaaga taatagtgat tttgaatgca gtaatttaga tttaaaaact
    20041 ttagaaaaaa aatatatcta taaaatttat aacgaaaata atagaaatac tacaaaaacc
    20101 tgtgaaattc taaagataac tcgctccact ctatggcgta agttaaaaga aatagaagat
    20161 gatgtttaaa aataatacat acctatatat atcaaaacgt tttatgttta attttaatac
    20221 ataaggcgtt tatttgtttt caataaaaaa tacaattata tgataaaaag aatctttgta
    20281 agtgaaattc tcatcaatca tacctttaat tataagtaat ctacagcatt tcaatcgatt
    20341 attaaaaata atcatgataa ctaaaaatac aaactctata tattggcata gtaattgctt
    20401 ttataatacc tatataaaaa tgaaagggag tgatactaga tgcacatctt aaaatcagtg
    20461 aaaaagatac caggaggact tatggtctgt cccttgttat tgggagcact atttaataca
    20521 gtatgtccac aagctcttga aattggagga ttcacaacat ccttatttaa aactggtgca
    20581 atgagtatac ttgctctatt ttgtctatgc aatggagctc aaatcaatat caggcaagct
    20641 ggtaagccat tgactaaagg tatagtactt acagcaacaa aatttataat tggtgcagta
    20701 ttaggtatta ttgttagtaa atttattgga cctaaaggta taattggtat tacacctctt
    20761 gccatagttg ctaccatgac taattcaaat ggaggtctat ttgctgctct tgcaggtgaa
    20821 tatggtgact ccacagatgt tggagcaata tctatcttat ctctaaatga tggtcctttt
    20881 tttacaatgc ttgcttttgg agtaactgga cttgcaaatg tacctatagt agcactattt
    20941 gcagcactta taccaatact acttggattt atacttggta accttgatga agatatacga
    21001 gaatttcttg cacctggtac aacattatta attcctttct tcgcttttcc tttaggagca
    21061 gcattaaact ttaatcaaat tataactgct ggactacctg gagttgtact tggtttagga
    21121 gttactataa taacaggtat gggtggctac tttgtaatga aacttatacg tgcagaacat
    21181 ccagcagtag gtgcagctac aggtacaaca gccggaaatg cagctggtac tcctgaagct
    21241 ttagcagcta tagaccctac tctagctaca atagcagctg tttcaacagt acaggttgct
    21301 gctgctatta ttgttacagc aatatgttgt ccaatgttag tttcctatct agataaaaga
    21361 gaaaaaaaga aaaaatctat ttttaaaaca aataaaaata ttgaagtaaa ttaatactta
    21421 aggaggtaaa attaatgaat gcaattattc atgcaaatga aaaagataat ctagttacat
    21481 gtgtcagacc tttagttaaa ggtgaaaaag tttcaattga tggaaagtct tacatagtaa
    21541 atgataatat acctgtcttt cataagatgg ctacagaaga tgtaaaaaaa ggtgatgttg
    21601 tatacaaata cggtgaaatt ataggaattg caacagttga cataaaaact ggtgactatg
    21661 ttcatgtaca taacattgaa agtacacgtg gtcgtggaga taaaaaatag gaggaagtta
    21721 aaatgaaatt aatgggttat ttaagagaaa atggtcagtt tggtattcgt aatcatgttt
    21781 taattattcc aacatctgta tgttcaagtg agacagctac aagaatagca tcacttgtgc
    21841 ctggagcaat agcaatccct catcaacatg gatgttgtca aattggttct gatatagagc
    21901 ttacagcaaa gacattaata ggatttggaa aaaatcctaa tgttgccgca gttttagtag
    21961 ttggtcttgg atgtgatggt attcaagcaa aagaattagc atctgaaata gctacaacag
    22021 gaaaaaaggt agattacgtt gttatacaag aatgtggtgg aacattaaaa acagtttcta
    22081 agggaactga aatagtaagt aaaatggctc gtgaagtatc aaaagaagta agagttgaat
    22141 ttggtatgag tgaaattaca ttagcacttg aatgtggtgg ttctgaccca acaagtggaa
    22201 tagcttcaaa cccttcaata ggcgttgcat caaaccttct tgtagatgaa ggtggaagta
    22261 gcatactaag tgagactaca gaagtaattg gtgcagaaca tttgttggct acccgttttg
    22321 aagatgaaga aatgaaagat aagtttctta aatttgtaag tgatgtagaa aaaagagcaa
    22381 ttgctatggg agaagattta cgtagtggtc aacctactcc aggtaataaa gctggtggac
    22441 tttcaacaat tgaagaaaaa tcacttgggt gtatgtataa ggcaggcaat aagccattca
    22501 aaggtgctct tgaatatgct gatattgtac ctcctgataa aaaaggatta tattttatgg
    22561 atactccagg tcaagatata gattctatca ctggtatggt agcaggtggt gcacaaattg
    22621 taatcttttc aactggtaga ggtactccaa caggaagccc tatttcacca gttattaaaa
    22681 tcactgggaa tagtgataca tacaacaaaa tgccagacaa tatcgatata aatgcaggta
    22741 gaattataac agatggtgct aaaatagcag atataggtca agaaatattt aatgaaataa
    22801 tagaagtctg taatggtaaa cataccaaag ctgaaagtct tggtcataga gaatttggca
    22861 tttacagaat ttcatctaca ttttagattg taacaaaata tcttttataa atataatact
    22921 tatgtagata cataagctaa aagttctttc taatcctata aaaattttct atactgaaaa
    22981 ggaactgtat caaaattatt ttgaaaacag ttcctttttt aacctctttt actcaaaata
    23041 ttataaaata agatttaaac aataaacgtg tcttgattaa tctctaagaa gacataaata
    23101 aagctaaatg taaagtgaga taaataaaat ttaatatctt tgtatgaaaa gatatttggt
    23161 ataatatgtc tgagagaatt cttatttgta aacaaataaa ggatggagga tgaaacaaaa
    23221 gaatgaactt tgaaaacaca aaaaataaaa aaataatagc tactttacta ttgacactcc
    23281 ttttaatcgt gtcattaaca tgtgtcaatt ttattatgaa tctaaataaa gtaacacata
    23341 atgaaacaga acgatatctt gtagaagttt cacaaagtat ttccactaca attaatgtga
    23401 aatgtaaaag tatatttagg acactatatt ctatgggaga tacttatttt gagattaatg
    23461 atagtgaaaa agaagtcaat agatacttat caaaaaaatt aaaattattt gaatttgatt
    23521 ggttaggtat tatagattct aatggaaatt ttgtaagtgc ccttaaagat acaggtaatg
    23581 ttaaaggaca agacttttat agaaaagccc ttcaaggtaa agaaacaatt actcctgtta
    23641 aatcacaatc tggtacatat ggaattttat attctgtacc actatacaat ggcgataaaa
    23701 ttgttggagc tgttgctgct tggaatacta ttgatactat gagaaattta ttaagtgtag
    23761 aaagctttca tggtgaagga ttttcccaaa ttatcgacca agatggaaat tttattgtaa
    23821 gttcagcaaa caaaaatgct ccaaaaaatg tggtaaattt ttttgacatg attaaacacc
    23881 aaggaaaaca ggttgataaa aataaacttg aagaaatgaa aataaactta aaaaagaaca
    23941 aaactggttc tatgtattat acattaaatg atggtatttc taaggcaatg cattatcttc
    24001 cattacaaga agaaaactta tacctccttt cagttgttcc aacaaaaaca gcaagtgcac
    24061 agtttgattt acttctaaaa aaagcaatct tcatcaatat tttaattgtt atactatttt
    24121 tattgcttat tatattgatt atgtttataa atcaaaagaa cagggcacaa cttataaaaa
    24181 tcgcctatgt agactctgta actaaaggtt acagtaaagc acgttttgat attgaagcta
    24241 aaaaaattat acagtcatct tcatcagaaa gctattcatt ggtatctata aatattcaga
    24301 aattcaaact tattaatgat tcttttggta gtgaagcagg agataaaaca ttaaagtaca
    24361 tacatgatgt cattagtaat tatctagaac caggagaatt gctttgtcga gtttctaatg
    24421 accagtttaa tgtacttatt aaaactattc ctcaaaaaga aattcttaag tacatagaaa
    24481 atatcaccaa tgatattaat agtttcaata aaaatgaaga atgtaaatat tttatagctc
    24541 tatctatagg tgtatataaa attgatgacc caaatctacc tttagtttca attcaagacc
    24601 gtgcaaatgt tgcacgaaaa aataataaag gaaacattgg aaatcatcca ctttatacat
    24661 gtgtttttta tagtgattta gagcgtttaa aaatgattaa agaaaaagaa atggaaaata
    24721 gaatggagga agcattaaat aataacgaat ttatagtata tcttcagcct aaaataagcc
    24781 tcaaagataa tactattgta ggtgcagaag cattagtaag atggcaagac ccaaataaag
    24841 gccttatacc accagacgag tttattcctt tctttgaaaa aaatggtttt attacaaaac
    24901 tcgaccacta tgtttttgaa aaagtatgta gtatgataag aaaatggata gataatggag
    24961 aaactccaat gcctgtttca gttaattttt cacgtgctaa tttaaataat atagattttt
    25021 tagaaaaata cagaatgctt cgtaataaat acaacattcc tgctaagctc ttagaaattg
    25081 aattaactga aacacttgta tttgaaaatc tccaaaaatt aattaatata atagaccaaa
    25141 tccatgaaga aggttttcaa tgttcactag atgactttgg aagtggatac tcttcactca
    25201 atatgttaaa agaaataaaa gttgacacat ataaaacttg accgtgcttt ttttagctca
    25261 cctaatgcag ataatattgc tgaaaatcat gtaatagaat ctatagttaa tttggcaaaa
    25321 aaattaaata tgaatagtat atcagaaggt gttgaaacaa tcttgcaaat ggattatctt
    25381 aaaaaaatta attgtgatat gatacaagga tatgtttttt caaaacctct gcctcaagaa
    25441 atatttgaga aaatgacttt tggaaaaaaa ctagaagaaa ccagtatgga tagttccgtt
    25501 taaataaaat aaaaaacttg tctctataaa ataattttaa tcattttata aagacaagtc
    25561 tttttatttt ccaatttaat tttattttct aaatttctta tactcggctt gttttaaatt
    25621 ccctttttaa gaataataat acgattatca tagcaataaa atctgcaact ggctgtgcca
    25681 accaaacacc atctaaatta aattgaattg gaagtacaat gattaatggt ataaataaaa
    25741 taaattgtct taaaagagtt aaaaacattg aatgtttaac tttacttata cactgaaaat
    25801 acacaggtcc tacaatagaa atccccatta taggcaatgt aattagattt atgcttatac
    25861 ctcttactgc tatatccatc aaatctgaat ctttattaaa tatacctaca aatacttctg
    25921 ggaaaacttg tactattaaa aatccaaatg acaatatgac aactgacact atgatagata
    25981 atattaaagt tttctttgca cgttcatatt gttttgcacc ataattgtat gatattatag
    26041 tttgcatacc ttgattcaat ccaaacacag gcatcataaa catcaataaa atagatgtaa
    26101 gtgctgtcat agccccaata gctaaatctc caccataaac ctttagagaa ttgtttgtaa
    26161 acatgtgagt tatacttata gctacttcca tagcaaaagg tgtcattcct attgcaaata
    26221 ccttctttac tatatcttta ttcaatttta agttacattt ttttagtttt aaagtggact
    26281 tccctcttat aaaataatat gttacccaaa agaatactac tatttgacat agtactgttg
    26341 ctatagctgc tccttttata cctaaattaa acacaaatat aaatataggg tccaatatca
    26401 ggtttaatac acatcctaca atcattgtcc ttgctgctaa ttttggatta ccttctgctc
    26461 taattgcatt attaagagaa aatgcaacta aattaaatat acttccaatc aatatgacac
    26521 tcatatagtc ttttgcataa aatattgaat ctttacttgc acccaaaata aaaagtatat
    26581 cttctaagaa aactaatcct aatatagtta taattaaaga gataattata gataatgtca
    26641 aagcattacc taatatcttc tctgcttctt ctctatttct ttcccctaat tttatagaca
    26701 atcttgtgct agcacctact gataccaaca ttccaaaagc tattattaga gtaaatactg
    26761 gcatagttac accaagacct gcaatagcta tagagccaat accttccata gaaccaataa
    26821 aagctctatc tactacatta taaagtgaag ttaccatcat tgctattatt gccggtatcg
    26881 aatacctaaa taataaaatc catatttttt catgtcttaa tgcttcttga ttctccatgt
    26941 tgtcaccatt tacaccatgt cataagttat acaaattggt ttatttgttc ttgggtctgt
    27001 tgctatttct gcatcaatat taaataattc ttttagatta tccttcgtca taacatcata
    27061 tgcatcacct tcacaaacta ttttaccttt cttaatacct atcatgtggt cagcaaatct
    27121 tgctgcatta ttaagttcat gtattaccat gacaatagtt cttccttgtt ttttatttag
    27181 ttcatctaat aattttagta tctctaattg atgtgccaaa tctaaatatg ttgtaggctc
    27241 atccagtaat aatatatcag tttcttgtgc caaagccata gctatccatg ccctttgtct
    27301 ttgtcctcct gataaatctt ccatatttct atccttaaat tctgcaattc cagtaacttc
    27361 taaactccaa tttacaatct ctctgtcttc tttactagaa ttaccaaatc cacttttatg
    27421 aggaaatctt ccataagaaa ttaattctga aacggtaaga ccactaggag cttgagggct
    27481 ttgtggaagt acagccatat cctttgctat ttctttagac ttctttttgt agatgtcctc
    27541 tccatttata tatattttcc cactattagg gctaataatt ctacctatag ttttaagtat
    27601 tgtcgatttt ccacaaccat tagcccctat gatggtagtt atttttcctt ttggtatatt
    27661 taaatttaaa ttttttataa tatctgtgtt tccatatgat acatttagat tcttagtatt
    27721 tatacagttc ataacaacac cctttcctaa tcatttacca acattaaata aataaagtac
    27781 ggcactccta ttatagaaac tactatacct actggtattt ctataggtgc tagaagattt
    27841 cttgatatag tatctgctat taaaagtaat aatgttccta tcaatgctga tactggtatt
    27901 aatcttttat gctttggtcc tattattttt ctacctatat gtggagctat taaacctaaa
    27961 aatgaaatac tacctgctac tgctgtcgat acaccagata aaattactgc atatattata
    28021 agtcttcttc tttgtttttc tacatctaca ccaagactta tagatacttc atcacccaaa
    28081 tttaaaacat ctatatattt agatttataa atagttatac ccataaaaat cactataaat
    28141 ggaagcacag ctattacata tttccaactg gttccccaaa tgcttcctga tgtccatgcc
    28201 ataaccctat taaattcttg tgttgtaaat ttcaattgga atatcgtcaa aattgaagta
    28261 aaagctatgt ttacacctat accaataagt agtaatcttg acgaatttat accacctttc
    28321 catgcaagag aatatataag aaatgctcca aataaagctc ctataagtgc aacaataggc
    28381 attgtaaata cagtcaagtt actcatacct tcatatacat taccattcat aaggtatata
    28441 taaactacta caaacaatgc agcacctgaa tttattccca aaattccaga atcagctaaa
    28501 tcattctttg taactccttg aagtattaca cctgctgttg ataatgcaga accaaccaaa
    28561 agtgctatta ctattcttgg taatcttaat ttaaatattg caatttcatg attacgctga
    28621 ccctgcccta aaaaagtctt tataacatcc attggttcta tagaaaatga gcccatattt
    28681 aaactcaata aaaaagtgat aaaaataagc accattaaaa ttgatataac aagtaatgtt
    28741 ttagaattta tttttataat atttttcata gtacctattt ctcccccttt ctaacaaggt
    28801 atataaatat tggcactcct ataagtgctg ttatagaacc tactggtgtc tcatatggag
    28861 gatttatcat cctacttaat atatctgtat atacaagcaa tacagctcct aatactaaag
    28921 agctcggtat tatatactta taatctgaac ctactattcc tttagctatt tgaggaacta
    28981 taagacctat aaaaataata ttaccagaca ctgacacaga tgctccagtc attaatatta
    29041 caagtactat acatataaat ctaacaaagt tagttttttg tcctaatcct attgccactt
    29101 cttctccaag acttaatata gttattcttg gagccataat aatagctaaa ataaatccaa
    29161 taccaccagc tacaaatagc aattttatac cttcccactt cactcctaca agccctcctg
    29221 atatccagaa acttaattgt tgagataggt taaaatacat agatattgct gatgccaaag
    29281 aaattagcaa tgtaccaaga gcgactcctg caagagctaa ttttacatta ttaactcttc
    29341 ctcttgattt agaacttata aaatatataa ataatccact tatacttgct ccaataaatg
    29401 caaacatcat tacactaaaa cttccatgta taagttgagg aagttttttt tgaagtacca
    29461 gtgatatcga aattgcgaat gtagctcctt gtgtaattcc tataacagat ggttcagcta
    29521 taggatttct cgttattcct tgcattattg ccccagaaac tgctaaaaac cctccaacaa
    29581 gtgcagctgc tattgctctt ggaagtctaa catcctttac tattctcata tttattccat
    29641 cttccatttt tatcaaacta tctatgacag ttgatagatt catatctttt gccccaatag
    29701 ttatggataa tacaattcca aatacaagta caactatact tactaatatc aacaaataag
    29761 ttatattttt tttactcagc ttagtcaatt atcctacctc cttttccctt ttaatcgtca
    29821 gtataatatc atctattaag tattttaatt ttaagattta ttaaaaatag gtgtgaaaaa
    29881 tgaatatcat tatctcacac ctactaagtt aagaattact ttgttaattc atttttaact
    29941 gattctaata ataactcttt tccaattgga ttgtatgatt gactgaaaaa tggagcagca
    30001 tcaagtattg ttacattacc atcttttact gctcttattt gagaccagat agcactattt
    30061 tctaaatctt ttttatctgc ttctgtagca attacaacta tatggtctgc atctatatct
    30121 gttaaacctt ccatacttac cattggtagt gttattccat cctgttttgg catattctta
    30181 ggtctagcta atttcatatc atcattgatt agagtaccta ttccaccatc actaaatacc
    30241 ataaattgac ctgaacttgc caacactggt aaataagttt tttctccatt cttttctata
    30301 acttccttac ctaactttgt agctttttca tcatacttct gtagccaact tttagcttct
    30361 tcttctttgt caaataactt tgaaacatca gttaacttgc ttctccagtc atttgcataa
    30421 tctttcatca taactacagg agctatttct tttaattggt catatatttt ttcttgtctt
    30481 tgactcatta ttattaaatc aggatttact tctaatatag cttccatatc catagtatcc
    30541 atcattgagt gcccaactat ctttacacct ttaagctctt ctcttatgta acttggtaat
    30601 ttatcagttt catatgagtc tacatttgct gttgcaacag gcttataacc tgctaataat
    30661 agttcttcac tacttcctga tatatcaact atttttttag gatttgatgg tatcttaacc
    30721 tctcctttaa cagattgtac aactcttgtc tctgatttat ctttatcctc tgtattctta
    30781 tctgaacatg ctgtaacaag tactaacgta gttataatag atataaatat tgcaagtgat
    30841 tttatttttt tcatgattac ttctcctact tgtttattat acttacatga tattgattat
    30901 cataagcaca tatttattat agcatttttc tatttttagt caatattatt ttgtaaaagg
    30961 ataaaaattc ctaattaatc ttaattatat atagcttaga taaggttttc ttatattaaa
    31021 cagtattttt tttaagaatt ggacacaaac acaatgactt ttaggttaaa caatgataaa
    31081 atgcaattta tagataatga atttagtaag gaggattcaa aacatggtac atttagtata
    31141 ttgtgataat gcaggaaaaa aaggagaaaa ggtcttagat aaaatcttgg ctggaacaaa
    31201 aacaatggtt attagaggtg ctgctggtag aaaaatacca catagtagag tatttgaaga
    31261 tgagttactt tattttatgg aaaaaggaac tggaaaaata tctgcaaaag ccactgttaa
    31321 aaaagtagaa aactatgtta aattaacaga agatgaaatt tctaaaattt taaatgaaaa
    31381 tcaaccaaaa ttaaatttat ctgaaaagca aaaagttcgt tggcataaaa aatgtttatg
    31441 cttagttgaa tttgaaaatg ttgaagaaat aacacctctt gattttgacc atcaaggaaa
    31501 tatggatgat tggcttattg ttgaaaaaat tgaagatgta gttgttggta ctagtatacc
    31561 ttacaattat gagaagtcta aattttaaag tatcaataac ataatactat attgctaaac
    31621 tctacttaaa taaaaaaaga gtgcatttaa taattataaa aattattttt atacactctt
    31681 ttttaataat aaatttaaat tacttacttt ctaatctttc atatacatct ataaattctt
    31741 ctgctaattg ttgaaaattc atagctgtca ttaaatggtc ttgtgcatga ataagtataa
    31801 cacttatttc agttttatta ccattagctt cattttgtat caattctgtt tggaatttat
    31861 gagctttatg aattgattct ttcgactttt caatacattc tctagcttta tctatattcc
    31921 cgctctttgc ttcttttatt gcttcaaatg ctagcccttt cgcatcacct gcaaatccaa
    31981 ttattccaaa agatatctct atcatcttct catccattta ttcgacctcc taaatatctc
    32041 tatagcttga tatgactaat ccattctttt ctaaaaattc tttgactttt ttagatgtaa
    32101 gtatcttgtg ctctttcgtt ctatcaatag cataagatgt agaatttaaa atataatcat
    32161 ctaaaaaagc tgggtgagac ataatatcca ctacatcata cttcattatt tcgtctatat
    32221 tttttataaa atattcttca cttacatttt ccttataaaa actatctatt aaaggaacta
    32281 ctttagaata ctctaaatta tattcaaatc cacctcttat tggaagatta tacttggtta
    32341 caatcttctc tactactggc tttaaactta ctaaagtatg gatatgatgg tgactatcta
    32401 aatgagatat atctattcca agccctttta ccctatctat ttgagcacaa agttctctat
    32461 aaatctcatc acaatccatt ttttcaataa tttcgtctgt aatcctccta ataaaaaaac
    32521 cgtctttatc aacaatagtt tttaagttag ataataatgg tctaccacaa cttaaagtca
    32581 tatgaactcc acaatttaaa gttttatttt ctttaagtaa gcctactcca tgttctaccc
    32641 caggcatatt tgccatcata gaagtagacc taactatacc attattatga gctgaaatta
    32701 ttccatagtt cacagcttca caatatccaa aatcatctgc atttattata attttagtca
    32761 taccataacc tactttctat agacaactat ctattaaatc taggaagata atctttatga
    32821 gcttccaaca tttcgtctaa tatagttttt gctaagtcat cagatggaat caatgggttt
    32881 atacaaagtg ccaaaagagc agattcataa tcgccatata cagctgcttt agctaccaat
    32941 acttcaaatg atttgatttg gcttactaat ccatgcacag aatctggtaa atatcctata
    33001 cttattggtt ttggaccatt tttggttatt acactactca cttctaccgc ttgttcatct
    33061 ttaaaatctc ttatagaacc attgtttaat gtattaacta cttggatatc ttttttgtca
    33121 ttgtatatag aacttattaa attacaagca gcatcactat agtaagcccc tcctcttttt
    33181 tcaagttgag gtggttttac atctaatttt tcatccttat ataattcaaa taattgttct
    33241 tccaattctt taactacttg acctctagct tttccctctt taaactctct caactcatcc
    33301 tcaagcattt ctttagtttt atagtagtat ctatgatatg gacaaggtat tgcacccaaa
    33361 gattttacaa attcagcatt aaaatcaatt gcctttatat tttgcatact tatatctgct
    33421 ttgacaaact tatcaattgc ttcttttgta acatcttctc catctaaaga tacatttaga
    33481 ccataaacca tatgattaag acctgcaaaa tccatactta ttctgtcact ttctacatta
    33541 aatagtttgg caacatcatt ttttaaatga attggcacat tgcatagacc tatatatctt
    33601 ctaaaattag tatatttgaa tacagcctct gttattattc ctgttggatt tgtaaaattc
    33661 accatccatg catttggaca taattcttcc acatctttta ttatatcaaa tataactggt
    33721 attgtgcgaa gggctttaaa taaacctcca gcaccattag tttcctgccc cataactcca
    33781 tgagataaag gaatagtttc atcttttatt ctcgcatcta aaagacctac tctaagttgt
    33841 gttgtcacaa agtctgcatc tcttagagct tctcttctat ctaaagtaag atttattttc
    33901 atatctactc cagctttttt taccatcctc ttagctagat ttccaactat ctctaatttt
    33961 tcttttccag cttctatatc tacaagccat aattccttta caggtaactc ttcatatcta
    34021 tttataaaac cctctacaag ctcaggagta taacttgaac ctcctccaat tgtaactatt
    34081 tttagtccct ttttcatctc attataccat ccttacctat aatttaatat actctacaaa
    34141 accctataca tttatttacc gaaataaaac tacctagttg ttaattttca atttattagc
    34201 ttccattttt tcagacgcta tgacaaatgg aatatatatt aatattgata atattaaatt
    34261 aaatagtgct aaagctccac cagtccagtc acctgtagcc atcgctccac ctaatatagg
    34321 aggtgttacc caaggtattt taggtaaaat tactggtgct actaatccaa aatctattgc
    34381 taagtatgat acagcactac atatcactgg tgcaagtaca aatggaatca taaatatagg
    34441 atttaaaact attggaagtc cgaatatcaa tggttctcct atattaaata ttgcaggtgg
    34501 cccacctaat actatcattt ctttacgtct tctcccagct attaataaag ctactattaa
    34561 tcccaatacc attccagaac cacctaaata tacaaatgca tcaaagaatg cacctgcaag
    34621 tacatggtat ccttccgttg ctcctgcttg agccaaggca gcattttctc cacctaattt
    34681 cataagtata gtttctgtaa aaggaagtgc tatatttgca ccatgaagtc caacagtcca
    34741 aagtatatga attataaatg caataagcat tgtagaacct agactatcag ctacatttga
    34801 tagcggtgct cctaaataag tatttaaaat atctgttaag aaacttccat tagaaagcat
    34861 ttttataaat attcctatta cagtaaatat cattatagtt aacattcctg gtattaactt
    34921 tgcaaatgat cttgaaactg ctggtggaac tccatctggc atttttatag ttaatttctt
    34981 taccttagat aatcttacaa atatctcagt tgataataat cctattaata tagaagagaa
    35041 taaagctgct gtacctaagt aggtttgttg tatcattccc catccttcaa ctactgtagt
    35101 tcctccctca ggaactattt taccaatttg tggagccatt ataaaaaaga tagataaagc
    35161 tataagccca gattgtaacc catcactctc ataagatttt gctagaaaat aagcaacacc
    35221 tattactaag aatactgcca ttgtacctat tgctccccac caaaggtcgc ctccaaatgt
    35281 ggtccaattt tctccaaata tacttgccat caaatttttg tatgcttcca atggtaagtt
    35341 atttatcaat gttcccaagg cacctaccat agttataggt atcattacta taaatgcatc
    35401 tcttactgct actaagtgcc tttgagctcc tattttagca gctacaggca ctatatattt
    35461 atccataaat gacatgaatt tttccatttt acatcctcca gtacaacttt attttgaact
    35521 atttaactct acagctctat ctaacacagc ttttccatta catcttccat aatccatcat
    35581 atttataact tctactggaa tattatatgg ttttgccatt tcagttgctt ttcctaatac
    35641 atatctaact tgaggcccta aaagtaagac atcacaattt tctatttcat tttttaagtt
    35701 cacttctgat atagcccata tttttgcttc tataccgttt tcctttgctg catcctccat
    35761 ttttgtaact aataaactag ttgacattcc tgctgaacaa gctaacatta tttttatcat
    35821 tttttcccct ccaaattaga ttcattaaat attttttaag tcataaattt tttaaactat
    35881 acatttaaaa tatgcttttc tattaatttt ttcttaatgt atatatctta tttttaaatg
    35941 tatatacatt taattcttga tattattata taccaaatgt atatacattt caagaaaact
    36001 ttttcatttt atttaaattt tattcgacaa cagcattcaa agttaatgta tatccatagt
    36061 gatatgtgtg tgagtactca aaaatctcac tattttgtaa cttacaaatt tggcttatat
    36121 ataaaagtgg ctctggttct tctaatttta gattatccat acattcttca ttcgatatta
    36181 cagcttgtac ttctctctct gacatggcta tcttgtatcc acacacttct tcaacaaaat
    36241 tataaagaga attttcacaa tgagtcttat ttaaatttgg aaataactta actggcatat
    36301 aagtaatcat atatgaaact cttgcatcat tggctaatct tactcttttt atttcccaaa
    36361 cattttcttc taaacttata ttcaacttac ttgataaatt ttcatctgcc tgaactattt
    36421 caagagatac caatatatta gatactttat agcctttact ttccatctct ttagtaaatc
    36481 cacttacaga cgatatatta tcatatatat tatttgcaat aactatacta cctacacctc
    36541 tttgtctagt tatatagcct tctttaacta gattattaag tgcagacctt acagtcattc
    36601 tagttacatt aaattcttca ctcagctgtt tttcagaagg gattaaatcc ccttctttca
    36661 aactgtctga atttattaac tctctaacat gattttctat aactttataa attggctctt
    36721 tcatttaatt cactccttat taattaaatc ttttatataa taagataatt ttatatacaa
    36781 ataaagaaaa tgtctataca tttaagataa tttaaatttt attcagacat cttgtacaac
    36841 tttccgagtt ttaataaaga tataaataga cttatcatta atataccttt taatatactt
    36901 gataaggtta tactccacca tacaccattt agacccaaca tttctggtct agatataaag
    36961 taagccaatg gtactcttgc accagtcagt atagtaatta taatagaagg tatataggtt
    37021 ctgcctaatc ctttgaaagc tcctgttgtt attatttcta aacacataaa aaattgagaa
    37081 tagcctaata ttttaagata aattgctcct ttttctattg cctcactttc atctataaaa
    37141 atagaaaata tactctctcc tgcaaatact aataccaaag tagttattat cccaagtaca
    37201 gaagatacag ttatagctat tttgcaacct ttatttattc tagaatactt cttggcacca
    37261 taattttgtc caacaaaact gcctaatgca actgatagcc cttcagccgt catccaggaa
    37321 attgcttcta tttgtgagcc tactttttgt actgcaacag ccacaggccc ccatgatgct
    37381 actattactc ctaatagcat tgagaatact gtaaacatac cactttgtat tgctataggt
    37441 aatcccaatt tatacagaac tttataatat ttagtctcta tttctttaaa tagtcttaat
    37501 ttaaaatatt cttctttact tttaactatt atatatataa aacatgtagt aactactatc
    37561 tgagcaaata cagttgcaat agcagctcct gcaacaccaa gttttggagc aaatccccat
    37621 ccaaaaatta atataggatc aagtataata ttagttatta atcctactgt attaatacga
    37681 aaaggagttt tactatttcc aagaccgttg aaaattgcag taaatactgg attaataaaa
    37741 taaaatacca tacctagagc tactattatc aaatactgtc tagacatggt tataacttct
    37801 aagtctccta atctaaaaaa acctatcaat tgtttattaa gtactattaa agaaattgta
    37861 tatattattg ctagtataat atttatttct attgctgact tcatatatga tttagtagtg
    37921 cttatattat ttgcaccaat actttgtgct acttttatct ctccacctac ttttgaaatc
    37981 ataataaatg ccattgcaag ccatggaaaa aaaccagctg ttccaactgc agctactgct
    38041 ttacttccgg ctttaccaac ccatatcata tctatcatgt tataccccat ctgtataaat
    38101 gaagtcccca ttattggaag tgatagctta agtaattttt ctgtaattct tccttctgtt
    38161 aaattaattc tgtctttcat tttccacctc ttttatatta aatttatttg cttatatagc
    38221 tagattaatc attttatttg attgagttca ctatccttca atttatatta tcatatctca
    38281 agattgcatc tcaaccatac ttatgtttaa gataaagtat tttacctatc tctgataaaa
    38341 ttaatactta tgaatataaa tatagtcatt tcatcaatac atattataac ccttaactta
    38401 acttcaatta agtatacata ctgtaatcaa ttagaatatt ttataatgta tcttccatta
    38461 agaaataaca aatataagtg atttatctat aattttattt atacataaaa tagtatactg
    38521 caataataaa aaaactatat ttgaatactt taagcatgtt tactaattgt aatttccaca
    38581 caaatttgat aatatatgaa tatattatgg tgaaatttat agatatatat taattatggg
    38641 gagattgtgg gaggttcttt tcacaagaca tttaagctat gaaaataaat aaaaaattta
    38701 atagagttga tatgcaggtt tcaatactta ctgcaattat tgtaataata tcttcctcat
    38761 gtgtatattt ttttaattat acattaactt ataagagcat gatatactct ttaagtgaga
    38821 ggtcaaaaca tatctatgaa tatgtagaga gaaatattga taaaaatacc tttactgaaa
    38881 ttaattctaa agaagaccaa tcaaaaaagt cttataaaag ttctaaaatc ctattagaat
    38941 ctgtaaaaaa tactactgga gtcatgtatc tatatactgc taaaaaaaca aaagatggat
    39001 cactagtata tgttgttgat ggtttaaatt catctagaag tgattttaga aatgctggtg
    39061 atttgataga aaaagagatt tggggagatc ttaacaaagc attagataat catatattgt
    39121 tacctaaaaa gattaaatca acatcttggg gatacatatt tatatcgtat tttcctattc
    39181 acaatgatgt tggtaaggtt gttggagtaa taggaattga atttgaagca aaacatcaat
    39241 acaatacatt taaatttata agtatagtta caccaataat agcattatta acttgtctaa
    39301 tatcagcatt gattgcagtg attctattta aaagaatatc taatcctaca tatactgatt
    39361 ttgctaatac agattattta acaggcctaa aaaatagaaa tgcttttgaa atagatatga
    39421 ataacttaaa caattcaaat ctaaagaatc taatatctat catatcaata gatttagacg
    39481 gtttaaaaaa gattaatgat aaatttggcc atcagacagg agacttatat attaagcaag
    39541 caagtaaaat tatacaagat gtaataaata aaaaatatat agtttatcgt attggaggtg
    39601 atgaatacat aattattcta aaaaatttat ctcacaaaga aataaatagt attataaata
    39661 atattaattt aaaaatagtt gaagaaaact caactaatga attaaaatta tcaatgtcta
    39721 ttggatatgc tatttttgat gaaaaagtag atgtttcttt atttgataca tatcgtcgtg
    39781 cagattctca aatgtatgat aacaaaaaga aaattaataa ataatatcaa taataaattt
    39841 aaaaagtcta ttctttaaat aataaatcat aagaatagac tttttaaatt tgtgttttta
    39901 taagataaat tatttaatta aagtttgttc ttttttctaa acgattcttt ataaattcat
    39961 atattacttt cactaatata tttgtgacta atattaacac agctagtgct gctgcctgtg
    40021 cagtactccc cttatcatct agttgtacaa ttgatattgc agctactttt gaacttgcag
    40081 tatatataaa aactagtgct gatattgtca ccatagagtt tagaaaaaag tacataaagt
    40141 tctctaaaac tgctggcaaa caaagtggta tagttacgtt cttaagaatt gatgcgctgt
    40201 ttattcccat tgatttagct accatgtcca attctttatc tactttctta atagcagtag
    40261 tagctgttat aaatgctact gaaaagaaat gaactatatt acatataacc attataagta
    40321 atgttccata taatccatta aacaaatttt taatgtatat tgtatccata aaattaaact
    40381 ctaatttatt aaaaaataat acataagcta tacctaaaac taatcctggc aatgccatag
    40441 gcaatgtact taaaaaatac ccaaatgatt ttaaatatgg agctttttct gttttttcat
    40501 ttaaatatgc aaataagaaa acaaagctcg tccctagaat agctgtcaat agtgacattt
    40561 ttattgaatt tataaatggt ttaattccat caatactgtt tttcatagaa aagtgttcca
    40621 gtgtaagtct taaatcatat ggccaaactg atattaatga ggataagatt acagttaaca
    40681 ttacagctat tataccaaat gcaataattc ctacaacccc tcctaaaata ctatctctta
    40741 acttattagt tttaacctta tatggaattg actttgaagt tatatatgag ttttgatttt
    40801 tttcaatttt tttagttact ataaacgata ttattgcagg tattaaaagt aatattgata
    40861 cagttgctcc cattggcata ttctgttgcc ctataatttg cttatataca tctattgata
    40921 atacattaaa ctctcctcct atcacctttg gagctccaaa atctgtaaaa cataatgtaa
    40981 atgatacgaa tgcagaactt attaaagagt attttatact tgggattgtt atgcttataa
    41041 attctcttat cttgcttatc cccatagtat tactagcttc atatagtcta taatcggttg
    41101 aacttagaga tatataaagt atttgaaagg attgaggaaa tacatatata atttgtgcca
    41161 atattattcc cactgctcca tatattggaa catgcactcc aagtaaatta gttaccaaac
    41221 cttgatttcc aaataaatat actagaccta ttgcatgcat cattgttgga gcaaacatag
    41281 gaaacatagc taatgattta aaaaaacctt taaatttaat ctttgttcta gttaatgcat
    41341 atgcatatac taatgcaagt gttagtgata ttacagttga tataactgat acaaatactg
    41401 tattttttag agaatttaat agagattcag aagccaagta ttcttgaaag ttttgtaatc
    41461 ctacaaagac tccatcttta tctaaaaaag cctgtacaaa tagatatatt ataggtgcta
    41521 ataaaaatat tactaaagac ataactaata ctgtaagcat acattttttt atatctaaat
    41581 tcatttttga tttaagactt atacttttag aacttatagc attattattc atacacttat
    41641 gctcctttaa cttttggata ctttaaatag tatttttcgt ctatacttat ttttacaagg
    41701 tcaccttcta ctaaatttaa attaacccac tcttttatag aaacatcact tattatgaaa
    41761 ttttcattta atttatcttt tatttcaact ctcaataaat tccctctaaa ctctatattt
    41821 gatattatac cttggtagtt ttcttttgtc gatttctcta tttgaacata ttctggtctt
    41881 acagttaata tagaatctcc attatcaaaa cagtttgtat ctcctataaa ttgagctgta
    41941 aataggtttt gaggattttg gtatatttct tctggagtcc ctatttgcat tatatctcct
    42001 ccatttagaa tagctatttt atctgccata gttatagctt cttcttggtc atgtgttacc
    42061 attattgtcg ttatattaag ttctttttgt aatcttttaa tgtccattct aagcttgtgt
    42121 ctaacctttg catctaatgc ggacattggt tcatctaaaa gtaaaaactt tggttcaaga
    42181 gctaatgctc ttgctattgc aatcctctgt tgttgcccac ctgataatgc tttaggatat
    42241 ttatgagctt cattagtcaa tccaactgtt tcaagtactt ccttaacttt attatctatt
    42301 ttttcttttg aaacttttct ctcttttagt ggaaaagcta tattgttata agcagtcata
    42361 ttcggaaata atgcatatga ttgaaatact ataccaaaac ctctctttga tggctctaaa
    42421 tttgtaatat ctttatcctg gagaattata gttccactat ttacatcttc aagacctgct
    42481 attattctaa gtaatgtagt tttaccacat ccactaggtc cgagtaaaca tagaaattcc
    42541 ccttcttcaa tatccaaact aatattattt aaaacccttt tttggtcata acttttaaac
    42601 acattattta tttttaagta actcatatct tatctctcct tatatagtta tttttttatt
    42661 ttaaatttta tatcctactt tttcttctaa aattctttca tctaaattat taatttaaac
    42721 cttacttact ttcagatttt gaaccgtatt ttgattccca agttttaagt actgtacttc
    42781 tgtttttggc agcagagttt aaatcaactt cttttataag ctgttcaaat ggttgtttag
    42841 aataaccttt tggaactgga ttatatgtct ttatggaagt aactgctact tcatgtgcat
    42901 atctatccat agctgaatca cttattgccc aatctaaaaa tagctttgct tcttttttta
    42961 tattatcttt tttaactaag gcatttgctt ctaagtccca acctgaacct tcctttggaa
    43021 atacaacctc tataggttct ccactagata attgttgtgt agctctatat ccaagtgtaa
    43081 tacctattgg atactctcca gagccagcta acttcgcagg ttttgaacct gagtgtgtat
    43141 atgtagctat atttttatgt aatttatcca tgtaattgta agcatctttt tcacccatca
    43201 tttgaataag ccctgatact gtaagatacc ccgttccaga tgatgctgga tttggcattg
    43261 ttataagtcc tttatattct ggttttatta aatcttcata actttttgga atatctatac
    43321 ctagtttctt aagttcctta taattaacta ctattgctgt ctctgggaca ctcattccta
    43381 cccaagatac atcatcttca gtatctttaa attttttatc aactttatca taatttttag
    43441 gcttatatgc ttcaagtgca ccatcttttt ttagctctat catgttcatt gctgataatc
    43501 cccatataat atctgcttgt ggattatctt tttctgctaa tagttttgaa gctattacac
    43561 catgagaatc cataactatc tctacatcta tattgggata ctcttctcta aaaccttcca
    43621 tataataagc tatctgctct tcctctagtg ctgcatatat tgtaagttta ttatttcctt
    43681 ttccttgagt agtttgtggt gttgttgata tgcaacttgt cataaatgta atcactacaa
    43741 tgcacagaca agtaaatata aattctttca tatcttcccc ctttgtgttt tttccttttt
    43801 ttatttgttt tttattgttt ttgcttatgt ttatataata cacctaattt gttaatataa
    43861 agttaagtgt aaattaacag ttcgttaatt tttagaaatt tttgttaaat atattatttt
    43921 tagttaaata cagtctgttt ttaaacaata tattaatttt tatagtatct acattttaat
    43981 ttaaacataa aaaataagtc taacctctat aaagtagaat gttagactta tttttataag
    44041 tatttaatta tacaaccaaa tcattttttt tcttttcttc aagtgctttt ttaagcacca
    44101 tatccttaac cttcataagt ctagtagtac ttgctctctc attttcttca agcttcatag
    44161 ctatatactt aatagtctca atgtaatttg gtatcattac attttcaaga gcattaacac
    44221 gtctacgtgt cttttctatc tcttgtgcaa gaagctgtgc acttttttca ctttctgcaa
    44281 gtcttaaaag tggttgcata gcatctgaga aagcttccat agcagaatct aattcacctg
    44341 atgtaaaagc aagaccataa ggataaatat cactttgatt gttttcagtt ttaaagtcaa
    44401 acacaggaac atcaacactc attatatttc tcgtagaaac atctactgaa actgattgct
    44461 ttggcatcat aagtgctgaa cccagatact cctgactcat aactgctctt gcgattataa
    44521 agtttttata agcagtatca agagcatttt ctgcttcttc acgcaatcgc ttattttctc
    44581 ttacaatctc aagaaattgt ttcataagtt catcaagttt atctttaaga agcttatgac
    44641 ctcttgtagc agttttaagg agtttcttaa gtctagtcat ttccatacgt gttggattta
    44701 tatttaatct agccacagat atcactcctt aggcatatat ttttcaaaat attcatcacg
    44761 gatacgttta agttcacttt ttggtaacat actaagaagc ttccatccga tttctaatgt
    44821 ctgctcaata gttctatcag ttctaaatcc ttgtgaaaca tattctttct caaattcatc
    44881 tgcaaactta gcatacatta aatcaatctc agaaagtgca gattcaccaa gtatagccat
    44941 aagttctttt gcatccttac ctcttgaata agctgcaaaa agctggttca ttgtatctgc
    45001 atggtcttca cgagtcttac ctttaccaat acctttatct tttagacgag aaagtgatgg
    45061 taaaacatct ataggaggct gtatatcttt tttataaagt tcacggctaa gtataatttg
    45121 cccttctgta atgtatcctg taaggtcagg aattggatgt gtcttatcat cctcaggcat
    45181 tgtaagtatt ggaatcatag ttatagaccc ttcatgccct ttcatttttc ctgctctttc
    45241 atacatagta gcaaggtcag tataaagata tcctggatat ccacgacgtc ctggaacttc
    45301 ttttttagct gctgaaactt cacgcaatgc ctctgcatag tttgtaatat ccgttattat
    45361 aacaagtaca tgcatatctt gctcaaaagc aaggtattct gctgctgtaa gtgccattct
    45421 aggtgtagat acacgctcta cagctgggtc atttgcaagg tttacaaaca ctacagaacg
    45481 gtcgattgca ccagttgctt taaaatcgct tataaaaaat tcagcatctt caaaagttat
    45541 accaactgca gcaaatacaa cggcgaactt agaatcagtt ccacgtactt ttgcctgtct
    45601 tgcaatctga actgcaagat tggcatgtgg caaaccagac cctgagaata taggaagttt
    45661 ttgccctcta accaatgtat taagtccatc tatagcagag actccagttt gtataaattc
    45721 ggccggataa tcacgtgctg ctggatttat tggagctcca tttatatcaa gtcttttatc
    45781 tggtataatt tctggacctc catcaatagg tctacccatt ccactaaaaa cacggcctaa
    45841 tatatctggt gaaactccaa agtcaagact ctttcctaaa aaacgaactt tactttcagc
    45901 aaggtttata cctgttgagc tttcgaaaag ctgaacaagt gcagtatctc catttacctc
    45961 tagaactttg caacggcgaa tttctccatt tgaaagttca atttctccaa gttcatcaaa
    46021 ttttacacct tctacgccgt ttattaacat aagaggaccg gctacctctt gtattgactt
    46081 atattccttt atcatagttc ttcagccccc ctctttttaa taaggtctgc aagctcgttg
    46141 tctatttcat cttcaattga atcataagct gcatctatat cgccttcttc tacatactta
    46201 gcacgaccaa tcttttcaag aactgaaagc ttgataatat cgtttatagt aacattttgc
    46261 ttgatagcat cttgtgctga cttatagaat tttaatataa gtcccatcat tctatattgt
    46321 ttatgaagtg atgtataagt atcaacttca tggaaagagt tttgatgaag gaagtcttct
    46381 cttatagaac gagtaacctc tagtatcaat ctatctccat ctgaaagtga atcaacccca
    46441 accaattgaa ctatttcttg aagttcagat tcaacttgta aaagtttcat agcttgagct
    46501 ctttgagctg agaaattatc atttacattt ttatctgccc atacatcaac tttttcctga
    46561 tagagtgaat aactagtcaa ccagttaatt gctgggaaat gacgtttata tgctaaagat
    46621 gcatcaagac cccagaatac ttttactata cgaagcgttg cttggctgac aggttctgat
    46681 gtatcaccac caggaggaga aactgcacca attgctgtaa gtgttccttc tctttcatcc
    46741 atacctagac aatttacctt tcctgctctc tcatagaatt gagcaagacg tgaacctaag
    46801 tatgcaggat aaccttcttc accaggcatc tcctctaaac gaccactcat ctctctaaga
    46861 gcctcagccc atcttgatgt agagtctgcc ataagtgcaa cactatatcc catatctcta
    46921 aaatattcag ctattgtaat accagtgtat atagaagctt cacgtgcagc aactggcata
    46981 tctgatgtat ttgctataag cacagttctt tgcataagtg actcgcctgt tcttgggtct
    47041 tttaattcag gaaattcaag aagaacatct gtcatttcat ttccacgctc gccacagcct
    47101 atatatacaa ctatatctgc atctgcccat ttagcaagct gatgctgtgt aacagttttt
    47161 ccacttccaa aaggtcccgg tatagctgct accccacctt ttgtgattgg gaaaaatgta
    47221 tctataactc tttgacctgt aacaagaagt gaatctggtg ttttcttttc tctatatggt
    47281 ctttcttttc taactggcca tttttgcatc atagttacag gtatatcatt acctttttca
    47341 tctgtaataa cacaaactgt atcttcaaca gtaaattcac cagaatatat ttcttttata
    47401 gtacccttaa ctccataagg aaccataatt ttacattcta ctactgctgt ttcttgaacg
    47461 ccaccaatta tatctcctgc tacaacctta tcaccaacag attttttagg tttaaattcc
    47521 cacttagttg ttctatcaag tgaagatact tcaacacctt tagttatatt agtacctgaa
    47581 atatcataca ttttttcaag tggacgttga ataccatcat aaatagttga aataagacct
    47641 ggtccaagtt caacactcat aggcattcca agagaaacta cttcttcccc tggtcctaga
    47701 ccggaagttt cctcataaac ctgtatagaa gctttatctc catgcatttc tataatctcg
    47761 cctataagat gtttatctga aactcttacg acgtcaaaca tattcgcatc tctcatgccc
    47821 tccgctacaa caagcggtcc tgacaccttt acaattgtgc ctgttttcat attctctcac
    47881 ctgcaatcat atactttatc aaaatttaaa tattccctcc tatattttat tagcacatat
    47941 ctttagcacc aataaaattt gagattgtct tttattcaac tttcatctat tctttaaata
    48001 atatatctgc acctatagca cgtttactag attctcttac ttcattcata cctaatccca
    48061 tacttcctcc aatacctgga ataactataa tggcaggaag ttggtaatct ttgtattttg
    48121 ctattgattc ttttgcaagc aatgatgcct gttctgtaat ataaattatc gcatattcat
    48181 cttcaaccaa cttatgtata ctttttttaa tttcgtcact atcataggct gggaagatat
    48241 ctattccaag agctaaaaat cccatgatgc tatctttatc tccaactact cctaccttat
    48301 acataagcat cccttagcct ttcttttata gtatctgcgt ctatattatt aagcttacta
    48361 gtcaaaataa ttctaattgt ttttatctct gattctttag catataaata tgcaattagt
    48421 ggttctaatg taagaggctt aaattttgct cctctaacat attccataag atagtcatca
    48481 caaagttttt caaagacagt aaaaccacta tccatgccat ttttacagac atcagagtaa
    48541 gaagtagatt taaaacatga tgctggagta tctgaggaaa aagcttctaa gaatttttcc
    48601 ttatcaagtg agccacctga aacaaacaca ttcataaaca tatcaaaatc tttcttcata
    48661 tttttgactc ttataaaact ctttagattt gttaaatcgc aaactttcat aacataatct
    48721 attacaaatt tgttttggct ttctttagca gtttctttca tactggtaaa ggttgcttta
    48781 tctagaacaa tatcaaccat ctggccattt tgtgtcttat tataaacatc aaatgcctct
    48841 aatatagctg atgacattat cttaggtaaa tcactaaaac tacgatttgc taaagattct
    48901 ctaagcttaa taagaggaat tgtacctcca tcaattaaat atttctcacc atctacacca
    48961 gaaatttctt ctttaatcag cacttttaaa ttgtgatagt catttttata aagaaataca
    49021 tcaacaaatt tttcttcagg agctagactt ttaagaattt catatgtctt tgataattct
    49081 tgagtcaaaa tattctcaaa attatgtata ttattatttg atgtatcagc ataacctgcc
    49141 tcagctataa ttcttaaaga gtcttcaggg cttttggctt ctgccatttg aataaacatt
    49201 tgtctgttaa gaagctgttt ttcaagcact cttattcgtg caacggcata gggataagtt
    49261 ttttcttctg ccatttttta acccctcctt aattaaacaa aatttctgct gcaatttgtt
    49321 caatatattc atgctctact gcaattatgg cttcaaatga ataattgtac tcaatgtcac
    49381 cttttttaac tatgaaacct ccagtaatat ctctagtttc atcagacact ttaatgcctt
    49441 tttttgatag cacatctttt aatgtttttt tatctttttt agataatact atctctgaat
    49501 catctgtaca atttgatttt tcaatcatgt ttagtataat ctcttcatat tcattatctt
    49561 taagatttaa aagtttgttt ttagcttcta aaattacctc ttctaaaatc tcttgttttt
    49621 ttgataatat ttgcttttta gcctccatat aagctcctga tatttcctta gaagccgctt
    49681 tttctgcttc tgcctctgca agctttgtat aggaagccat ttccttttca gctttttcat
    49741 tagctgaatt tacttttaaa tctgcttcac ttttagcttt atccaatatt tcttgtgctt
    49801 cttgtttggc atcagctata attctgtcaa tcattttttg ttcattaccc ataggagtgc
    49861 ttcctccttt tcattttttt tacttatgaa ttataattta taattaacca attgcaattc
    49921 cattgtaagc taagaaagaa acaagtagtc ctaaaagagc atatgtttca actattgctg
    49981 caaatgttat agctttacca agttcttcag gtctttttgc aactattcca actcctgctg
    50041 ctgctgcttt accttgtgct atacctgata ctaaaccaac taaaccaatt ggaagtcctg
    50101 ccataagaag ttgtaaacct tgagctgatg ttggtattgc atctccacca ataatccctg
    50161 cttttgataa aataaggaaa gctatgataa atccatacag accttgtgta ccaggaagaa
    50221 gttgtaaaac tagaagttga ccgaatttac tagggtcttc tgttacaaca cctgctgcgg
    50281 cttgacctgc tattgaagta cctttagcag aacccatacc tgcaaataat gctgctatag
    50341 cagctcctga tattgccaaa aattgaccat ttcctaacgc gtttaaaaat tccatattta
    50401 catctccttt ttattaatgc ttgtatattt tgttttatac ttaaacggaa caaaaggaac
    50461 tcctccgcct tcataaaact tattgaaaaa ttctacatac tgtaacctac ttgtatgaac
    50521 atatgcacct agtgcattta taagaaggtt tattgtgtgt cctacaacac cgattacaac
    50581 tgcaagtatc ggaccagcta tagcccctaa aaggttgata acttgtgcta taactcctgt
    50641 tgttaaacaa agcgccataa ttcttgtata agataatata tcagcaaaat aacttgttat
    50701 gccatagaga cttgaaaatc ctttaaaaag cttaacagga atacctttaa agcttcttcc
    50761 ttgagtaagt acaagaccta tagcacctat aattgctaaa tattttccta cttctgaaaa
    50821 tacacctatg tcccctgcaa caaaaggtat tataagtaga catacacctg ttatacacaa
    50881 ataccaaaaa cctatgtcaa agattgcatc tattaccttt ccacttctta ttaatgtata
    50941 tgcttttatt cccaaaccta catatatatg gataataccg aacagtaacg acattcccat
    51001 aagtgtcata acatcctcta aaggattaat taatgctttt ataggaatta aatcccccaa
    51061 aatacccccg aatataagac cccatacagt agttgaaact ccacagatac caataagttt
    51121 aattaaattt ccttcacctt tttgtatctt taatttatat acaacaaatc cacagactac
    51181 tgcaattatt aacccatatg cggcgtcact tagcatcatt ccaaagaata caacaaagaa
    51241 gaaagttaaa attgtatttg ggtcaatatc ttttgtactt ggatagctgt acatgttagt
    51301 tacactttca aaaggtgtta ctaatttatt gttttcaagc agaattggga agccttcttc
    51361 tttacttcct tcttcagtct gaacacaaca atcaaacttt tctgtaattt ctttaattaa
    51421 ttcatctgcc cttttgcttg gtaaccaacc attaagacag aatgttgttt ttgttttgac
    51481 aagtctctct ataatctttt tttggtctct ttctatagtg taaaaatcat ataggttttc
    51541 aagcatgtgt atactatctg catgtctttt aatttcctct gttttgtcct tagaaacgtt
    51601 ttcctgccta attatcattt cattgtattt cttgatagct tgtaacggtg taccttcttc
    51661 atttggtaat gaaaccactg aaaaattaaa ttcttttaaa acttctaaaa catcatcaaa
    51721 agtttctttt aaagtaatta aataaacata gttcattaac ttgtcagaat tgacaatccc
    51781 aataacactt tctggtattt catcttctaa ttttactctt aaagcatcaa tatttgcgct
    51841 tatgggcaca gttccaagta tagtttttgt atacttagtt tccatatttt caagaggaat
    51901 atcaaagttc acccatggtt ctaacatact tttattgttg ttaagtaagt ttatgttaga
    51961 ccttattgta cctatctcct tgtgcaaatt gtttaactcc agagcttcag cataaacttg
    52021 cccttctttt tcactatcaa ttttgttaaa ctctcttttt ggtgcaagta gggatttttt
    52081 ttgtttcact agtgaagaaa caatattaat tgcttggttt acatgagaca ttttctgctc
    52141 tagcattata acttcagatt cttcactatc ttttacaaga taatttttta attcctcctc
    52201 ctcagtaaga aaggcactat catcaatctg aacaaaccca cggttcataa gtagctttaa
    52261 aatctggctt ttttgagctt ctaagccaac aatagatatt ttgttcatat taactattgc
    52321 catattatct cactaccttt ccaataaccg cttcaatagc cttacttttt ctttcttcag
    52381 cagttttttc aattttcaga cattcacttt tagcattagc taagatttta tcaacctctg
    52441 ctctactgtc ggtgactgcc ttctcaataa gagtttcttc cataagcttt gcttgttttc
    52501 ttacatcagc aaatatgctt tcacatttgt ttacagcatc agctctgata gactctgcat
    52561 cagtaacagc ttttactttg atactgtctg ctgtctgctc tgcctcaaca atgcttttta
    52621 ttatttcaaa agccatccaa atcacctctc ttaccttttt actatgtata taaccaatta
    52681 gattttttta ttctaattag attactacct cattgttaaa gtataaacag catttttata
    52741 taataattaa tatttttcaa cgtttatttc ttaataaaac atattttaga atagtacttg
    52801 cctagattta catccttttt tgacttactt ttagactatg acatgagtat ggtttttaaa
    52861 taccattatt ttcaataatt ataatttaaa gcgatatagt ttgtcaatag cgttattttg
    52921 ttttaaaatt aacgctatgt cgacatttta aatttttatt ttattttttt tataatttta
    52981 atttaattta ttacatataa aagtttttta tattcttttt caacctctaa cccttgaagt
    53041 ttattgtttt ttttgaattt ttagaaatat ctcgcactat tttatctaac ttttataaat
    53101 catcaagcta tatcgatttt tgtcacctta ttttcaatct aaatttttta tatatagtta
    53161 gaaataaatc aatattttta aagattgata aaacttacac ttagttctaa tagttttatt
    53221 ttaaggcaat gtattaatct taagtagata atatcattag ttactctata tattcgacaa
    53281 cattataaaa aaatcctcgt accaatcact ccaatcttca ataggatatg ctgctcctcc
    53341 atttacactt ttcagtaggt ttgatgtata ttcttctccc atggaaaaaa gttcccctac
    53401 tgttatatca taacctctag atgtaacaac cttacaaaat gaatccataa catcacgttg
    53461 ttctcttgtt tttataagtt cctttctaaa ttcatcatca ttcttagctt cttctaaaat
    53521 tttagttaat ttttcattca ttatgtattt ctccttttaa gtagtctttc tgtaaacttc
    53581 aataagcttt atataaaaag gaagccatcc taaataaact aagatgactt cgcttaactg
    53641 ttagcaacac atttactagt ataaaataat tggtgtacct ggttctatat tttcatatat
    53701 tttctttgcc ttagaaaaag gtgtatttac acatccatgt gaacctgaag acttatatat
    53761 acctccacca aaagaatttc tccaagtagc atcatgaatg cctatgttcc cattaaatgg
    53821 aagccaataa cttacaggtg aactgtaacc ttgaccagtt aatgaaacat ttctagcctt
    53881 ataattaaga ggatatatac ctgatggtgt agcaaatcct ctagctaaat cgcctgttac
    53941 aacatctgtt gatacaagca tttctccatt tttaaagaac cacatatgtt ggccagaaag
    54001 actaatctct acatatgtat ttccaatatc atctttatta cgagatacag ctttttgtat
    54061 gtaaataggt tctcttgtaa catttttacc agcttttaca acatcaacta atgcttcagc
    54121 ttctttcttt ttatctatca accaaccata aattccacct gaaattgtaa tatctttacc
    54181 tgtggcagtt ttaaatggtc ttgagtcacc aaaagtactg tattttttac ttaaacttct
    54241 tgtatattct accatagcat cattatcaaa agttatgtca taattctttt ctgagtctac
    54301 ttttaaccat ttattaattt cagaaccatc taaagtttcc ttacggtcac taaaatcata
    54361 tgtaacgact acaccaacat acttatctaa tgtcttaata gcttgtttca acttttctga
    54421 atcctttgtg ttgtttggtg cttcataaac tttactttca tccagagaaa tagaagtatt
    54481 cccagaatta attgagtttt gtactaactt ataaaaatca tcttttttca ctttgtttcc
    54541 aagtacctct ggtactataa cataagcgtt tttagtgcta tcatacttag gataagcact
    54601 cttaggttct acaacatttt tactatcaaa acaagataaa gcattaaacc ttttttctag
    54661 taaatcttta ttatatgaaa gagttatcat attattatac tctttagatt taaatattcc
    54721 accaatccat ccaatagcgc tttgactatc ttttatcttt tgaactttat catctggtgt
    54781 aaattttaaa tcaatatctt ttgcttttat ttgttctttc ttattgtttc tttcctctaa
    54841 gtttaaagta taggaattag tactagatgt taacaaatca tttacttgct caactgtttt
    54901 tcctgaagcc tttacgccat taatagtcgt tccaaagtaa aaatgatttc taaaaaagat
    54961 tgccattcct atataagcta caaacaaaac acctacaact atagctatct taaattttag
    55021 atttttttgt ccactttctt gttttacctc ttttccatca atcataatta aatccttcct
    55081 tacattgtaa ttacctatgt actttattgg tttttaaaca aaaccatgta tgccttattt
    55141 tatataccca aattactgta tcattgttta tatttttaaa tatatagtta tttccataaa
    55201 accattttat cttttagaca aaatgactat tataaatcac ccctttcaaa atcccttaaa
    55261 tacaatctct gctatattaa tatattacca tacttttaat aatcgtgggt tatctatctg
    55321 tttttgtaac actaaactac tcttttaaaa aagaaactaa ttttatgtta gtttctttat
    55381 cttaacttat ttttatattg aattttagct taacataacg ttgttatata gattctattt
    55441 aattatttta gtttctatat cttttccatc agcatattct ttaagtaact ccttagcata
    55501 tccaaaatat tcttcaatat cagattcttg actaaaagaa aatatacaaa ttaatatttc
    55561 atttgcatct tctgttatca ttgctctttc agaatcacta gttggactcc caaatttacc
    55621 cactgaatca gacaatatag gaagattttc tatatttatt aattctttcc caataccctt
    55681 atactgttct ccttcatctc ctacagtaaa acatactggt gaatgtaatt tgcttacatt
    55741 atatgtacct actggatata atgattttat tgatattaaa ttgtttattt ctactatatt
    55801 atttattgta taaagaccct tcccttgaat aattcttcta accaatgctt ctgaagatgt
    55861 tctatatcta cttggatttt ttccaagctc tttataagca tttcttgcat ctttaatttt
    55921 atctagtttc gtaatgtctt caacttttag actttgattt atagtatcac aaaactcatt
    55981 tatttcatta attaattttt ctgagctttt atttactgct acttttgctt gaatgcaacc
    56041 caacttagca ttaggccatc tttccttaag tttgtcatca atactcacat ctatcatact
    56101 taaacaactc ctatacacta aatttttatt aaagttttta tcatctatac attatagtac
    56161 tattcttttg ttaataacat gtttattagc aaaataaatt tatttttaat ataattttta
    56221 taaaatacaa ttattttttg ctttatatta aacaatacat tgataaaata aaaaaacact
    56281 aattatttag cagtgattta ttaaaatcaa acattcataa tagtgcttta tataaaaatt
    56341 aaattttgtt ttaaagtaaa tctaaaaaat tcttagctgg cattggtcgt gcaaaataaa
    56401 atccttgaac taaatcacat ccaaattgtt tcattaactc agcttgttct ttactctcaa
    56461 caccttctat aattacaact aaatctagtg attttgctag agacactatt gattttgcta
    56521 tattgcgact tctctcatca tgttcaatac cattaagaaa agacttatct agtttcaata
    56581 tatcaattgg catatctctt aaacaactaa tagaagaata tcctgtacca aagtcatcca
    56641 tagaaataga aaatccatac ttcctcaact catttaaaac attctttaaa atatttaact
    56701 cattaatagc cacagtttct gttatctcta tttcaattaa atctgaactt agattataca
    56761 tttgtattgt tttattgata aattttacaa tatctggttg atacaactca actctagata
    56821 aatttattga aactggaact atctttttac cttgcttttt ccattcagat aaatcattgc
    56881 aaaccctttc aaatacaaat ctcccaattt ttaaaatcaa cttacttttc tctgctattg
    56941 gaataaatac tgcgggactt ataaaaccat gttctggatg attccatctt attagtgctt
    57001 cactccctat catttctcca gttacaagtg aaaacttagg ttgataatac acttcaaatt
    57061 gattttttac caatgctatt tttatatcat ctaaaatcat tgattcttca ctaagcttat
    57121 tcctaacatc ttcattataa atagcataat ttatattttt acctttagca acagacctag
    57181 ccatatttgc tttatttaca gccttttgga tatctacttc accttcttca acaaaataaa
    57241 tacccacaca cagagaaatt tcaaatacta tactcaaatt actttcaata ttatttcgta
    57301 tactatcaat ttttcttata cgtttatttt ttccattttt ataatcacag aaaattgcaa
    57361 aataatcact tgaaagtcgt gcatatactt caccttctgt taattcttct tttaaagctt
    57421 ttgctatcgt aattaataaa ttgtcaccaa attcatatcc aaaagtatca ttaatcatct
    57481 taaagttatt aatatcaaaa tatactataa tataatttaa agatggttta tctaaaagat
    57541 acttactaca ctctctataa aatttatttt gatttcctat atgggtaact ttatcttcat
    57601 aagccaaact taatatttct ttttcattgg atttttttat ataaattata taaaaaataa
    57661 ttgcaataaa tattaatata ataaataaca ctgcatatat agctctgttg attatttgtt
    57721 ctgaattact aaatacaaca gtttctggaa ttgaaaaaat caaattccaa tcttttatat
    57781 aattattttc actattccca ttatccatag tagcatatcc taaatatctt ctttcttcca
    57841 acatatttaa tacagttgca cctgttttat tttcttgcaa ttcttttttt aatctattta
    57901 tttctcgaat atcattatcc tgttttaaca atttataaat attttttgat aggctatcct
    57961 cttgcggatg aaggataatt gtaccatcat ttcttacaac ataagatata ctattatttt
    58021 cataaaaaga tacattaata agtttcatca gagtattgat attgtaagta caatataaaa
    58081 ctccaactac tttatcatta tttaataatg gtactgaaat agtaatcttc tttatagact
    58141 tatttacttc atcaacatat ggacttgaaa catacttctt acctttaatt gagtttttga
    58201 aaaattctct atctttcact gaaaacttat cacctttggt attttcagca ttaccattta
    58261 tatcaactat tgccatagtg taaaattttt gattttccat ttcatctaaa agatttttca
    58321 ttttttcctc attaggtata tcttgattta aagcataata gttagaaaaa atatttaaaa
    58381 catctaaatc tttttcaatt tgtctttgtg ctagttgaga gccttgtact gcaacttctt
    58441 ttatatgtat ttttgcctct gacataagaa gatgttttgt atcttctata tagatatacc
    58501 ccattgtcaa aaataatgat gttaaaaaaa gaattgtaat taatgtaaaa cttttatttc
    58561 tccctgtcat tcgactcctc ccctaattag tcaatacttc atatagataa tatatccttt
    58621 ttataccgat tcatcattta tattgtatat aactattctt aaatgttaca cataaaatca
    58681 acctaataac cataaaaaca ttcttttatt atcataataa cactatttag ttgaatttta
    58741 aattaaagaa taaaaactat caatttttct aaacaaaaaa actcttatac aataaaactt
    58801 tgttttatgt ataagagttt ttattttatc tattttatag taaatttatc ttccataata
    58861 tgaatttaaa tacatatctt ttatttcatt cataagtgga tatcttggat ttgctcctgt
    58921 acattggtca tcaaatgctt gaatcaccat ttcatctatt gaatccataa acttaggttc
    58981 ttcaactcca aactctttta tagatttagg aataccaact ttaagtttta aatcttcaat
    59041 agctaccaat aaactttgga atttctcttc atcagaattt ccctttaatc ctaaaaatga
    59101 agctatttca gcatatcttt ttaatgcttc tggatattta tattgagaga atgctcccat
    59161 tttctttggt gcatctgaag aattaaattt cataacttct gttatcaaaa gagcatttgc
    59221 aacaccatgt ggtacatggt ggaaagcacc taatttatga gccatagagt gacaaacacc
    59281 caaaaatgca tttgcaaaag ccatacctgc cattgtagaa gcatttgcca ttttttctct
    59341 agcttctggg tcttttgcac cattatcata tgcacgtgga agatattcaa atatactctt
    59401 aatggcttgt aaagctaatc catttgtata atcagttgca agcatagata catatgcttc
    59461 taatgcatga gttaatgcat ctataccaga agcagatgtt aagctttttg gcatattcat
    59521 catcatatca gaatcaacta tagccatatt tggcatcagt tcataatctg ctaatggata
    59581 ttttacccct gtatcttggt cagttataac agcaaatggt gttacttctg aaccagtacc
    59641 tgctgatgtt ggtatagcta caaaattagc tttttcaccc attttaggga atgtatatac
    59701 cctttttctt atatccataa atctcatagc taggtcttgg aaatctacat ctggatgctc
    59761 atacaatgtc cacattatct ttcctgcatc cattgcactt cctccaccta tagatattat
    59821 tacatctgga ttaaattctc tcatagcttt agcgcctatc ttagcacatt ccaaagttgg
    59881 gtctggttct acttcaaaga atgtagtgtg cttaatattc atttcatcta ataaatcagt
    59941 aactgcttta gtatatccat tattgtaaag gaatgtatct gttacaataa aagctctctt
    60001 cttattcatt acatctttaa gttcttttaa tgctacccct aaacaacctt ttttgaaata
    60061 aacttttcct ggtgatctaa accaaagcat attttctctc ctctcagcta ctgttttaat
    60121 attaagtaaa tgcttaactc ctacattttc agatactgaa tttccacccc aagacccaca
    60181 tcctaaagta agagaaggag ctagtttaaa attatataag tcccctatac caccttgaga
    60241 agaaggagta ttaattaaaa ttctacaagt tttcatggct gaagtaaact tatcaagttt
    60301 ttctctttga tttacatcat caatatataa tgaagatgta tgcccaaatc caccatcttc
    60361 tactaatttt tctgcttttc taactgcatt atcaaaatca ctggccttgt acattgcaag
    60421 tactggtgaa agtttctcat gagcaaaagc ttcttctatt tcaactgatt ctacttcacc
    60481 tattaaaacc ttagtatcta ctgggacttc aaagcctgca agttttgcta tagtacaagc
    60541 tgtttgccca actattttag aatttaatcc tccatttact aaaattatat ttcttatttt
    60601 ttctgtttca tctttatcta ataaataagc accacgctct ttaaattctt ttttgacttc
    60661 attgtatata ttttctaata ctataaccga ttgttcagaa gcacatatca taccattgtc
    60721 aaaagtctta gatacaagaa ttgagtttac agcagttttt atatctgcac tctcatcaat
    60781 tattgctgga gtattacctg caccaactcc aatagctggt tttccagatg aatatgctga
    60841 tttaaccatt ccaggacctc ctgtagcaag ggtcaaatcc acttctttca taacagttgt
    60901 agttaattct aaagatggct catctatcca tcctattatg ccttcaggag ctccagctaa
    60961 aacagcagcc tcaagaacaa cttttgcagc ctctatagta gaattttttg ctcttggatg
    61021 cggagagaaa attattccat ttctagtttt taaagctaaa agtgctttaa agatagcagt
    61081 agaagttgga ttagttgtag gtacaactgc tgcaataaca cctattggct cagcaatttt
    61141 agtcatacca aatgcttcgt ctttctctat aacaccacaa gttttagttt ctttatatgc
    61201 attatatata tactctgagg cataatgatt ctttataacc ttatcttcag caattcccat
    61261 accagtttcc ttttgtgcca ttatagctag aggaactctt tgcttattag ctgccaaaga
    61321 tgctgctaaa aaaattttat ctacctgctc ttgagtatat gtagcaaata ttttttgagc
    61381 ttctctgatt tttgctagtt ttttaactaa gctttcaacg ttatttacag tatctaaacc
    61441 aactgacata acttcatttt cttttttatt ttctattatt acttgttctt tatgagccat
    61501 tttaacaacc tcctgagata gttttttatt tattatgtta atttattaac attatagcat
    61561 ttactttttc tattttcaag ttattttttt aacattttat tttttatcta atataacatc
    61621 atttctacta ataatatcta gctttacaaa tacttaattt aactagatat cactttattt
    61681 tttacgcaaa tcactaataa aatcatctaa aaacttaagg ataacgttat ttttttaacg
    61741 tttatatttt tgtatttttt gcaaataaaa ctttataaaa agaattttta atatgatatt
    61801 ctatcaagtt taaaaataaa aatacttgaa aatgaaaata ataacttgat taacaagtta
    61861 aagtaaatat agttaaatgt aca
//
LOCUS       DAMJWO010000008        59169 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.009, whole genome shotgun sequence.
ACCESSION   DAMJWO010000008 DAMJWO010000000
VERSION     DAMJWO010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 59169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59169
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.009"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            67..2178
                     /locus_tag="PC366_000597"
     CDS             67..2178
                     /locus_tag="PC366_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HDF2576147.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANHPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGKGQN
                     KDNWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVAWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSTSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWATNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNNSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKTNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTAL
                     VYEAGDGINQNTLNTFLNLVK"
     gene            complement(2376..3341)
                     /locus_tag="PC366_000598"
     CDS             complement(2376..3341)
                     /locus_tag="PC366_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDF2576148.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLD
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTVEK
                     GEIRELNKFIPETYKWNKSDDKGSIQYIRNSGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(3626..4582)
                     /locus_tag="PC366_000599"
     CDS             complement(3626..4582)
                     /locus_tag="PC366_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDF2576149.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVDIP
                     GRGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPNLVNTILPYVKTNMNPNEIISLGKELLSIGNLNLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            4950..5738
                     /locus_tag="PC366_000600"
     CDS             4950..5738
                     /locus_tag="PC366_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2576150.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEDIKDDMMFISENGTLVVYKGKEILSNPLNKELVNEIIETTRSIKGKKI
                     VMSGKKYAYIESKDEAFIQEVSTYYAKFKIVDDLTKVEGDILKIAVFDFKGAEHNNNI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEHLKQIARFRAKRNTENGVVDKIKEVIKIG"
     gene            complement(5861..6331)
                     /locus_tag="PC366_000601"
     CDS             complement(5861..6331)
                     /locus_tag="PC366_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HDF2576151.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEDIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENATQIENKILNIIKK"
     gene            6470..7114
                     /gene="uppS"
                     /locus_tag="PC366_000602"
     CDS             6470..7114
                     /gene="uppS"
                     /locus_tag="PC366_000602"
                     /EC_number="2.5.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="di-trans,poly-cis-decaprenylcistransferase"
                     /protein_id="HDF2576152.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            7157..8062
                     /locus_tag="PC366_000603"
     CDS             7157..8062
                     /locus_tag="PC366_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2576153.1"
                     /translation="MKKKLLDGKITLIICKSVKIYTKKGEEMSKGNNNNNSRNKSKKT
                     SHLNRKKRKLNKKKLAVLICFTVLFLFIAFKATQGVVALVKSMDKSNKTSQQQKVNSE
                     QFDLGNEEENKKKKYTVFIDPGHGGNDKGTESKTSNRYEKDLNLQIAKKLANKLSKQK
                     DIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATD
                     GSKELAQTVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSEEQKIIN
                     EKYQDQLAEGIVQGVLSYLDSKGNK"
     gene            8377..9924
                     /locus_tag="PC366_000604"
     CDS             8377..9924
                     /locus_tag="PC366_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2576154.1"
                     /translation="MNKNSMTKIYSLNKIIFIIIGILGIVLLTRHIEVDIKVLILILL
                     TLFSINVFISYLKIKLYEDKINLGLINNSDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINDIYGYELGDEVLNNILSNLKNYFGKEAIYGKLKSDVFVLIIKLEN
                     REQKIPYLVNLIKNKIMILSQIDSFKMDINIEASIGIYKFNNNEIDIKKAIDNADMAR
                     LKSKGLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMVGPNKFIPIAEKNGLINNIGRWLIQEVFITINKWISEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMNISLDDFGVGNSNFINLKGIPLDIIKIDRSLILDIVTNTKTKFMVKAIINLSHDLN
                     VTVICEGVEDMHQVKVLSELGCNFIQGYVFFKPLDEMNYKKLLTDGSYINLKDTLLDK
                     CMTVEEE"
     gene            9927..10325
                     /locus_tag="PC366_000605"
     CDS             9927..10325
                     /locus_tag="PC366_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDF2576155.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDKPIDAKMILKSEDIPILTLYRL
                     LRKLCANNILTFNKEDGKTYMLNVSLDTISLRTIVEVIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            10365..12098
                     /locus_tag="PC366_000606"
     CDS             10365..12098
                     /locus_tag="PC366_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HDF2576156.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     RHILNYCIYGADIDEKAISILKDSLTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGVGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
                     VFKIKNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVDKSEY
                     RLIYSNDIDNENTNKKILDEIIGLYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSYEYLVGILNSSVYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
     gene            12330..13541
                     /locus_tag="PC366_000607"
     CDS             12330..13541
                     /locus_tag="PC366_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF2576157.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIIQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDASLRTVMESVIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRNLASNFEVRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            13733..13993
                     /locus_tag="PC366_000608"
     CDS             13733..13993
                     /locus_tag="PC366_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HDF2576158.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
     gene            14346..16058
                     /gene="ptsP"
                     /locus_tag="PC366_000609"
     CDS             14346..16058
                     /gene="ptsP"
                     /locus_tag="PC366_000609"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDF2576159.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLED
                     AVAVSKEELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTESVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDEETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEIQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLSMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASIHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADDVLNMGTAEEIKSYIEK
                     TFNI"
     gene            complement(16850..17515)
                     /locus_tag="PC366_000610"
     CDS             complement(16850..17515)
                     /locus_tag="PC366_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576160.1"
                     /translation="MKGNIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKINNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDD
                     NDNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDDDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAG
                     NLN"
     gene            17859..19289
                     /locus_tag="PC366_000611"
     CDS             17859..19289
                     /locus_tag="PC366_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF2576161.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDLKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEMCLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKALKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEDQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEEICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            19657..20235
                     /locus_tag="PC366_000612"
     CDS             19657..20235
                     /locus_tag="PC366_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HDF2576162.1"
                     /translation="MFKRYAEKMTSVLICNNMIDNNESKVYSYGFEILIAFIVNITTM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENINI
                     DLFKNIIMIIASVSWVGICVLCPIEHRSNPISDREKFVYKKTAIFISTVVLLITILSL
                     SLSIFVDYFTYSAFAMFWIFVMLVLGKLKAKV"
     gene            20265..20411
                     /locus_tag="PC366_000613"
     CDS             20265..20411
                     /locus_tag="PC366_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HDF2576163.1"
                     /translation="MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNL
                     KKTN"
     gene            20716..22095
                     /gene="scfB"
                     /locus_tag="PC366_000614"
     CDS             20716..22095
                     /gene="scfB"
                     /locus_tag="PC366_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HDF2576164.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVDYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSVTPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            22124..22621
                     /locus_tag="PC366_000615"
     CDS             22124..22621
                     /locus_tag="PC366_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HDF2576165.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKKYIDESYEWYLEAA
                     QNQKY"
     gene            22919..24583
                     /locus_tag="PC366_000616"
     CDS             22919..24583
                     /locus_tag="PC366_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HDF2576166.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERMKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIDIFKEEVGLSIEEIFLEFKEEPIAAASIGQVYEGVLKTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKVYSEYNTKKILVMEKVNGTKLSDVEKIRRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLIEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNVEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            24596..27046
                     /gene="recJ"
                     /locus_tag="PC366_000617"
     CDS             24596..27046
                     /gene="recJ"
                     /locus_tag="PC366_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HDF2576167.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKLAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYNVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQSEIPSAFAVINPKQEDCNYPFDSLCGCGVAFKMIQALTPKEEFKTSMYN
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILEEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLGIENGEATGSARS
                     IKGFNIFEALIKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NVNVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     SIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDVSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMVNIRETFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            27059..27571
                     /locus_tag="PC366_000618"
     CDS             27059..27571
                     /locus_tag="PC366_000618"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HDF2576168.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKDVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            27645..29852
                     /locus_tag="PC366_000619"
     CDS             27645..29852
                     /locus_tag="PC366_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003229747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HDF2576169.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            29877..30326
                     /locus_tag="PC366_000620"
     CDS             29877..30326
                     /locus_tag="PC366_000620"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HDF2576170.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNASRPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            30341..30955
                     /locus_tag="PC366_000621"
     CDS             30341..30955
                     /locus_tag="PC366_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2576171.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHVDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVSDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGDFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            31046..32602
                     /locus_tag="PC366_000622"
     CDS             31046..32602
                     /locus_tag="PC366_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HDF2576172.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFKDSNANNNIESKHLIN
                     RLIYENGVLFSSTEYYENGNLKYESIQNIENMNLEFLDGFDSSKTIEEFLNRLDSESK
                     RNFKKLCKENIKKSMFVVLKQVFNSYVPWGILTGIRPVKIVHNLMDKKLDDNSIRTIL
                     KDNYFIIDKKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKVIKETKKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIKEFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEELNMVKNTLEEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            32592..33854
                     /locus_tag="PC366_000623"
     CDS             32592..33854
                     /locus_tag="PC366_000623"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HDF2576173.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            33928..35715
                     /gene="aspS"
                     /locus_tag="PC366_000624"
     CDS             33928..35715
                     /gene="aspS"
                     /locus_tag="PC366_000624"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HDF2576174.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKEAFEKAEKLGAEFVIAVKGKVCERQSKNPNMPTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEAIFKEVLDVELALPL
                     PKMTYAEAMSKYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFNEEEMNAILTKMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKSSLRAKAYDIVLNGYEIGGGSVRISNSDIQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGTDNIREVIAFPKNQNA
                     VCPMTNAPTLAEDEQLEELSIKVDIKDNE"
     gene            36174..37406
                     /locus_tag="PC366_000625"
     CDS             36174..37406
                     /locus_tag="PC366_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HDF2576175.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYILMKCFGIKDK"
     gene            37420..38226
                     /locus_tag="PC366_000626"
     CDS             37420..38226
                     /locus_tag="PC366_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="HDF2576176.1"
                     /translation="MGRKVKIGIIQQHSVLGDVKKNIEKAVEMIDDLGKHGADIICLP
                     ELFATGYNLESLGGVKTLELIREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFDRKGKIMGEYCKNHLWSLEAVYFKGGEKVEVYDADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSSYNI"
     gene            complement(38338..39207)
                     /locus_tag="PC366_000627"
     CDS             complement(38338..39207)
                     /locus_tag="PC366_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2576177.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAAN
                     VLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            39578..41005
                     /locus_tag="PC366_000628"
     CDS             39578..41005
                     /locus_tag="PC366_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HDF2576178.1"
                     /translation="MKLTKSISSMLCLALVLSLSPVAYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNNLNSQTEKELK
                     RLGVKKVYIIGLSSSVSNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEGLKDISE
                     IAVVNGYTGLADAVSIASVAATNGMVILPVSDASGISSFKDFIESKNINKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKNQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFLNKNATSITQVGSGGNENAFKELKDLQANS
                     NNKRVMYVTNTDKVNIRNDATIEASVIGYLNNGDEVEVLDVLKTGWVKIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETIEIFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            complement(41081..41350)
                     /locus_tag="PC366_000629"
     CDS             complement(41081..41350)
                     /locus_tag="PC366_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576179.1"
                     /translation="MKFEYYYLIQDIAGILLAFIGLRMSIIGFRILSMKGISINTLLI
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMLIISIIINPRIKVSK"
     gene            complement(41353..42795)
                     /gene="nhaC"
                     /locus_tag="PC366_000630"
     CDS             complement(41353..42795)
                     /gene="nhaC"
                     /locus_tag="PC366_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDF2576180.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAATKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICIVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDILNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLITKIGKSRTKLVGSTFIVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLEFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDDEIEELEIFDTAQRRVD"
     gene            complement(42820..43986)
                     /locus_tag="PC366_000631"
     CDS             complement(42820..43986)
                     /locus_tag="PC366_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2576181.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRLEQEIYGYTTRPDSYNESIVNWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKANDKIMIQEPVYSPFNSVVKNNNRELIISPLQKLENGNYIMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVILPDEKDYKLLDDAFTRIDIKRNNCFSLV
                     ATEASYNNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDEELESVLVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIK"
     gene            complement(44211..46331)
                     /locus_tag="PC366_000632"
     CDS             complement(44211..46331)
                     /locus_tag="PC366_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2576182.1"
                     /translation="MKQMELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHYDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPTDAVILTPGEKILPKFKNCEVVDLKY
                     RIIDLSCIVEIATKTKLKHLIKDDLIKKYVEKIIPTSYSTGELLLDANKFERQFDLLL
                     SIIDDGIICTNNDGIIQFYNHIARKILSINANEMIDSFVGDCIKDINFQNILTNKTPF
                     FEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQAKLRAQLVNSGNISKYT
                     FDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELFAQSIHSASRRKDGPFVA
                     VNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNGTIFLDEIGEMDLNSQSK
                     LLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNMFRRDLYFRLNVLPLKIH
                     PLRERAADIFEIFGSLKYDIPCNFILSEEVKEIFKMYRWEGNVRELRNLGEYFCYLGK
                     DIIEICDLPEYILDTIDSNYSRTVCNKVSDNIKKYQFNIGKDKNIMKYDYNFKRSLDE
                     YIFILDNLKKAYDLKERIGRKSLCKIALEENRFLTEQQIRNMLLELQDFGLVDILVGR
                     GGSIITSKGVEFLKNINRSNKLNS"
     gene            46564..46965
                     /locus_tag="PC366_000633"
     CDS             46564..46965
                     /locus_tag="PC366_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576183.1"
                     /translation="MKKCLYCNRDIKSPNNKLAIKYDDNMNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILAFIVIITVLYFKQVGK"
     gene            47008..47301
                     /locus_tag="PC366_000634"
     CDS             47008..47301
                     /locus_tag="PC366_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HDF2576184.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            47316..47756
                     /locus_tag="PC366_000635"
     CDS             47316..47756
                     /locus_tag="PC366_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HDF2576185.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGMTTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(47848..48321)
                     /locus_tag="PC366_000636"
     CDS             complement(47848..48321)
                     /locus_tag="PC366_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF2576186.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGVTGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(48321..49109)
                     /locus_tag="PC366_000637"
     CDS             complement(48321..49109)
                     /locus_tag="PC366_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF2576187.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            49437..50681
                     /locus_tag="PC366_000638"
     CDS             49437..50681
                     /locus_tag="PC366_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDF2576188.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGIHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLINKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALVTSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            51004..52101
                     /locus_tag="PC366_000639"
     CDS             51004..52101
                     /locus_tag="PC366_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-diphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDF2576189.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEITIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDTLLHEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHVNHSTKKNILIMGGGLGLLPKSEQFYKELNSL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKDSDLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDATLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGACRECM"
     gene            52092..52790
                     /locus_tag="PC366_000640"
     CDS             52092..52790
                     /locus_tag="PC366_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2576190.1"
                     /translation="MYVVGLIIVVALIFLVHSIIPTYYNKLLNKEVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIVGLHSLEH
                     RNAWLYSYSYVKKDFIESTNIMKNLGVDVNYYRPPWGHTNIFSNSFVKKYNLKMTLWD
                     VMAEDWEKDSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKIAIPK
                     LKASGLKFVTPERM"
     gene            52793..53857
                     /locus_tag="PC366_000641"
     CDS             52793..53857
                     /locus_tag="PC366_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF2576191.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFAMMFIYVACEGINIYLGMKALNQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGIMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVIGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVIISQI
                     EEYVKGAQYIKQNPKLVVQILVITIVQITAMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     VVHVKSSEKVKAVKKVAYVR"
     gene            54040..54744
                     /locus_tag="PC366_000642"
     CDS             54040..54744
                     /locus_tag="PC366_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2576192.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LVDSTIDLIILDVVMPVKTGFVACNEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEREPNILKTKELCVNLDTQDVTLNGEPVF
                     LTTIEYSILILMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            54737..56059
                     /locus_tag="PC366_000643"
     CDS             54737..56059
                     /locus_tag="PC366_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2576193.1"
                     /translation="MINKIKPSKLGVILLIYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNQLMDNFQTYVNNNGIRADDGDDIAKWNSDNWFVSMKIYKGNKVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIVVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSH
                     TLENQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            56246..57619
                     /locus_tag="PC366_000644"
     CDS             56246..57619
                     /locus_tag="PC366_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576194.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISMAFYTLKRDINKGMFREE
                     LKGFESEEVEEFNGKSKIATILVALGFLADIIVMYIFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISAAAICGVSPIELAKRNFVPVITGLVVTT
                     IVAMFII"
     gene            complement(57992..58930)
                     /gene="pdaA"
                     /locus_tag="PC366_000645"
     CDS             complement(57992..58930)
                     /gene="pdaA"
                     /locus_tag="PC366_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HDF2576195.1"
                     /translation="MFRKVLHYLTLLSISIFFIVGCSNSQNNQNENQNKETQLQEDKE
                     KIDGGKDTSNVIVSDGTDKPSKATTNNDNNKLDVSSLDNTTLDWFYIPNNKHKTPEVN
                     TDIEFKFSDYDALYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTA
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKD
                     MVKFFRPPMGKYSEKSLAMTKNLGYKTVFWSFAYRDWDTDKQPSHEEATQKIMDNLHD
                     GSILLLHAVSKTSTEILNDFISNARKLGYEFELLEY"
BASE COUNT        23058 a         6582 c         9932 g        19597 t
ORIGIN      
        1 ttttagatat acttaataag aagtatattg tagaaaaaat aaatttaaaa aattaagggg
       61 gatgaaatga aaaaaataag tatattagta ttatcattga taatgacact tactatgtgt
      121 agtgtaagtt catttgccga ttcatcaaat gataaggaaa tgagagctgc ttggatatct
      181 acagtttata atttagactg gcctaagact aagaataatg aagccaagca aaaaaaggaa
      241 tacacagatt tattggacaa actaaaaagt gtaggaataa atacagcagt ggttcaagta
      301 agaccaaaat cagatgcttt atataaatca aatataaacc catggtctga atatcttacc
      361 ggtacacaag gtaaagaccc tggatatgac ccattaccat ttttaataga agaagcacat
      421 aaaagaggaa tggaatttca tgcatggttt aatccatata gaataactat ggcagatgag
      481 agcatagata aattgccagc aaaccatcca gcaaagaaaa atccaagctg ggtagttaaa
      541 catggaaata agtattacta cgacccaggt ttaccagaag ttagaaagta catagtggat
      601 agtatagcag aagtagttca aaattacgat atagatggag ttcattttga tgattacttc
      661 tatccaggag taagtttcaa tgatactgca acataccaaa aatatggaaa aggacaaaat
      721 aaggataatt ggagaagaga aaatgtaaat actctactta gagatgtaaa agcgtctata
      781 aagagtataa agcctaatgt tgtatttggt gtaagcccag caggtatatg gagaaataag
      841 agtagtgacc caacaggttc agatacatca ggtaatgaaa gttatgtagg tacatatgca
      901 gatacaagag catggataaa acaaggattg attgactatg tagttccaca actttactgg
      961 ccaattggtc ttaaagcagc agattattct aaattagtgg catggtgggc taatgaagta
     1021 aaaggaacaa atgtagactt atacatagga caaggtatat ataagcaagg tcaatctagt
     1081 tatggtggac aaaatatagc aaaagaaata gtacaacaag taacattaaa tagaaagtat
     1141 agtgaaataa aaggtagtat gtatttctca gctaaagata tagcaaatag tacttctata
     1201 caaaaggatt taaagagttt atattctagt agtgaagaac cagttactcc accatctaat
     1261 gttaaagtgg agaaattaag aggcgacgaa agatatgaca cagcagtagc aataagtaaa
     1321 aaaggttggg ctacaaattc agatacagta gtattagtaa atgggtactc tatagttgat
     1381 ggcataacat caacaccact tgctacatca aatgatgctc ctatactatt ggtaaataag
     1441 gataatatac ctacatccac taagaatgag ttaaaaagac ttaatccaag taaagttatt
     1501 ttaattggag gaaataactc tattggagat aaagttgaga gtgagataaa agatacattg
     1561 tcaaatgtat caataaatag agttggtggt tcagatagat atagtacatc tttaatgata
     1621 gcaaaagaat tagtaaaaac taatccagta gaaaaactat atataacaag tggtacaggt
     1681 gaagcagatt ctctttctat agcttcaaaa gcaggagaag aaaagcaacc aatagtacta
     1741 gtatcaaaag ataatgtaag tgatgaagtt tacaattgga tatcagattt aaaagtaaaa
     1801 gatgcttatt ttataggtgg taatctaagt atatctgatt cagtaataaa taagctggat
     1861 aaggtcatta caaatgatgt atctaaaaat agaatagctg gagaaaatag agaagaaaca
     1921 aatggaaaag taatacaaaa attctatcca aatgctgaat attcatcaat gtttgtaagt
     1981 aaaagtaatc aattggtaga tgcattaaca tcaggtcctt tagcagctaa attaaaatca
     2041 ccagtagtta tgcttggaaa tagtgtaaca tctgctcaga aaactgcttt agagcctaag
     2101 aaaactgctc tagtatacga agctggagat ggtataaatc aaaacacatt aaacactttc
     2161 ttaaacttag ttaagtaata aaaaagttaa tttaaaatac agagtatttt ataaatgtag
     2221 attaaaatga aaattatcat cataaattag aaaataaaaa agaactatat gcattttgta
     2281 atcaagtgta cacagcaact tgaaaataat tatgcgatat agttcttttt tagtaattaa
     2341 tcttatactt tttaataaac tttatgttga attttttatt gtttaaactc tatgtcatta
     2401 aatataaaat cgtgtaatat gtctaaagta tctgggtcaa atctaagaac ccatccagct
     2461 tttccatata taccacctgt actatgaatt tcatcatcaa taggaaattc aaattgctta
     2521 atatttaagt cacccatttt taaaacttga gctcctaaag aaagtattgc attaggcttc
     2581 atgttagttt taacatatgg aagaactgca tctaataaac ctggatattt agtaacaggt
     2641 aaagtttccg ttttcttgat tatagcttgt ataatctgtc tctgtctgcc atctctagca
     2701 aaggctgtat cgttgtgtct gatacgtgca aaagatagtg cctgatatcc atttagagtc
     2761 tgctttccag agtttctaat gtattgtatg ctacctttat catcactttt attccattta
     2821 taagtttcag gaataaattt atttagttct cgtatttctc ctttttcaac agtaacctca
     2881 acgccaccaa tagcatcaat tatatacata aatgattcga aattaacaca agcataattt
     2941 tgaatatcaa tattaaaatt ctcttcaatt gtttgtatta ataaatcagc ttgtccataa
     3001 gcataagcat gagtaagttt ttgtttacca tgaccaggga tgtctacata gctatcacga
     3061 gctaatgatg taagtttgat atcattgtgt ttgttatcaa tagtaagtat catcatagca
     3121 tctgaccttg aagaatcttc atttggtcta gcatctgttc ccataagtag tatgttaatt
     3181 atcccatctt catttttatg gtcattgtta tccaataaat cactacttat gctcgagtca
     3241 tgaatagcag ataatttata ataaaaatat ccatagacac ttatagggaa tattactacc
     3301 aagaaagcca gtagtataac aaatttcttt aattttgaca aaagtacccc ttctttcttc
     3361 tttttcctgt atatttttta atagcataca cttaattata ttaaagtatt gagatatatt
     3421 caatacttgt ttcagttaca aaaaaaagac aatgatataa tttataagaa aatttatcga
     3481 cctatatgta tagttaaaag tatatataat atatttttta aaagtaattt atattttaaa
     3541 ataaaaacac accccataaa tacaaagcaa tttgcattta agaggtatgt atttatcatc
     3601 aaattattgg tttgttttgg aatttctaat cttcaaccat aatatcttta aatatgaaat
     3661 catgcattgc atctagttca tattcctcaa aaggtattac atagcctgca ttacctattt
     3721 ttctaccatt ttcagtagaa agaggaaact ccatagattt caaatttaaa tttcctatac
     3781 ttaaaagttc ttttcctaaa gatattattt cattaggatt catattagtt tttacatacg
     3841 gaagtattgt gttaactaga ttaggatatt tagtgactgg taaatcctta acaccattta
     3901 ttaaactctg tataacactt ctttgtcttc tatctctttc atctgtacta tcattttttc
     3961 ttatacgaga aaatgcaagt gtctgatatc catttaattt ttgctcacca gaatttctta
     4021 tatatttaag agaaccttta ttgtcatttt tattccattt ataagtttca ggaataaatt
     4081 tatttaattc tcttatttca ctcttatcaa cagtaacagt aactccacct aaagcatcaa
     4141 ctatatccat aaaagagaaa aagtcaacta cggcgtagtt ttgtatatca agttggaagt
     4201 tttcttctat agtttctatt aataagttag cttgtccata tacgtaggca tgtgttaatt
     4261 tttgttctcc acgtcctggt atatcaacat aagtatctct atttaatgaa gttagcttaa
     4321 gacttttatt tttattatca atagtaagta tcatcatggc atcagaacga gaaacttctt
     4381 ctcctggtct tgcatctgta cctaacaata atatgtttgt gatattttct tcgtttttat
     4441 agtcattact actaagcgcc tctgtattta tactatcatc ttgtatagtt tttaatttag
     4501 taaaaacata tccatatata ctaacaggaa atgctataac taaaagggct agaaatataa
     4561 cgaacttttt gagtcctgac aataatatcc cctactttct aaatttttta attacacata
     4621 gttaattata ttaaaaattt gttacataag caataaaaaa cacaataaat tagcataagt
     4681 ttgtcataat ataattattt ttatagtatt ttatagaaga aagtgtgtag ttattattga
     4741 ttttattgga atataattgt atgaagactt aaatttttat aaactgatgt gtatattgaa
     4801 aaaaatattt tcctgaatgt agttatagca tcttatgaaa ggtgtaaatt gtaatttaaa
     4861 atttttagtg tataataaga attgaaaatt caaaccgata aaaattaata aaaaataatt
     4921 ataaattaat aatttggggg aggaaatgta tgataaaatt aatagcaaca gatttagatg
     4981 gaactttgtt agatgaaaag agcgaaataa atccagagtt ttataaagta tttaaaaaat
     5041 taagagagag agggataatg ttttctgctg ctagtggcag gcagtatcaa aatcttataa
     5101 aaaaatttga agatataaaa gatgatatga tgtttatatc agaaaatgga acactagtag
     5161 tatataaagg aaaagaaata ttatcaaatc ctttaaataa agaattagta aatgaaatca
     5221 tagagacaac aagaagtata aaagggaaaa aaattgtaat gagtgggaaa aaatacgctt
     5281 atatagaaag caaagatgaa gcgtttatac aagaggttag tacttattat gcaaagttta
     5341 aaattgtaga cgatttgacg aaagtagaag gcgatatatt gaagatagct gtatttgact
     5401 tcaaaggtgc agaacataat aataatatct actttgaaaa gttttctgat agagctcaag
     5461 tatgtatttc tggagtggag tggcttgatt taactgcaaa aggtgcaaat aaagggagtg
     5521 ccataaaaaa agtacaaaaa atgttagata taaaatatga agaaactatg gtatttggtg
     5581 accagttaaa tgatgtggaa atgatgaaaa gtgcctatca tagttatgcc atggaaaatg
     5641 caaatgaaca tttgaaacaa attgctagat ttagagcaaa aagaaatact gaaaatggcg
     5701 ttgtagataa gataaaagag gtcataaaaa ttggatagtc atatgtatag atgaaaaaga
     5761 ttattttgaa gaaatcaaaa aaatatcaat gtaattttga taaataagtt tatttatgcg
     5821 aaaattacat tgatatttaa taaacatcaa taatagatat ttattttttt atgatattca
     5881 gtattttgtt ttctatttga gttgcatttt cagcagaaat taaataaaca tatctacctg
     5941 ctttctcaat tatagtatta tttgctattt cagaattgat tttttctcca tgtccttctc
     6001 caaaaggtgc ttgtatcata tcttttttat aattttctag agttttatat attttatcta
     6061 cctcgtcagt ttttataacg ataatatctt ctagagataa tttttcagaa gaattaatta
     6121 caaaaccttg aattatgtct tcctctacat cattaaaata gttaaagtcc tttgcatcaa
     6181 agatttttga ttcttttata agtaaatcag aagattttaa tgcttttttt atttttgatg
     6241 tagaaacgtt tttgtaatca ccacttgaag aacaactaac cattcctaat gataagatta
     6301 tcgaaaaaaa caatattaaa atttttttca tgataaacct ccaagttttt taaactctgt
     6361 cttaaattag tttactacat aattatataa aaataaatgt atttaatgtt acagttttga
     6421 ttaataatgt aatattttga taataatacc tattgagagg tgattagaaa tgagaatacc
     6481 aaaacatgta ggaattatac cggatggaaa tagaaggtgg gcaagtcaaa atggtatgac
     6541 aaaagataaa ggatatgaaa gtggaataga ccctggatta gagtcttata gattatgtag
     6601 agatttaggc tgtgaagagg tgacttttta tggatttaca actgataata caagacgtcc
     6661 atcagtgcag acaaaagctt ttacaaaagc atgtattgat gctgcaaata tattaataga
     6721 tgaaggtgct gctttattag ttgtaggaaa tacaaaatct ccaatgtttc cagaagaatt
     6781 attaccatat actaatagaa ttaaagccaa agaaggtcaa ataaaagcaa atcttctggt
     6841 aaattatggg tggtattggg acttaaataa tatatcagga gtagaaaatg taaataaaaa
     6901 taatatacag gattacatac agtcatttga tgtatccaga ctagatttaa taatcagatg
     6961 gggtggaaga aggagattaa gtggtttcct tcctgtacaa tcaatttatg cagattttta
     7021 tgttatagat aattattggc cagattttaa gagtgacgat ataaaggacg catttagttg
     7081 gtatgataca caagatgtca ctttaggtgg ataattaaaa atattctgat ttaaggttgt
     7141 agagtgtttt aaattattga aaaaaaaact tcttgatggt aaaataacac taataatatg
     7201 taaaagtgta aaaatttata ccaagaaggg tgaagaaatg tcaaaaggca ataataacaa
     7261 taattcaaga aacaaatcta aaaagaccag tcatctgaat agaaaaaagc gaaaattaaa
     7321 taagaaaaag ttagcagtgt tgatttgctt tacagtttta tttttattta ttgcatttaa
     7381 ggctactcaa ggtgtagtag ctttggtaaa aagtatggat aaaagtaata aaactagtca
     7441 acaacaaaaa gttaactcag aacaatttga ccttggtaat gaagaggaaa ataaaaagaa
     7501 aaaatatact gtatttatag acccaggtca tggaggcaat gataaaggaa ctgaaagcaa
     7561 gaccagtaat agatatgaaa aagacctaaa tctacaaatt gcaaaaaaat tagcaaataa
     7621 attatctaaa caaaaggata ttcaagtagt agtatccaga actgatgata catatatatc
     7681 attaaaggat agagctatct tagcaaataa tagttctgct gatgtgcttg tttctattca
     7741 tttaaatgca gagaaaaatg gtaatacagc aacaggtata gaaacttggt ataggaataa
     7801 agctacagat ggttcaaaag aacttgcaca gacagtacaa agtactatag tatcctatgt
     7861 taaagttaga gataggggaa tagttgaaaa taactttgaa gtacttagag aatcaaatat
     7921 gcctgctata ttaatagagt gtggtttttt aacaacacct tcagaggaac aaaaaataat
     7981 aaatgaaaaa tatcaagacc aacttgcgga aggaattgtt caaggtgtac tttcatacct
     8041 agattctaaa gggaataagt aagttaactt tactttaatg tgaggataaa tttaaaagtt
     8101 taactgtgta aattgtatta actttatttc gtaatgttgg aaacattgtt tgaatttaga
     8161 aactatgaaa ttagaaatta ttttatctat atctaatttc atagtttttt ttgcaaaaaa
     8221 tttatagtta taaaatttaa aaaaataaat ttagtataat gtaatgtagt tatttatatg
     8281 tgattttaac ttgcattgat ttgctatcaa ttgtgcttta taattagtat atataaagtt
     8341 taactgtaag ataatttaaa aaatagggga atttatatga ataaaaatag catgacaaaa
     8401 atttacagtt taaataaaat aatttttatt ataattggaa ttttaggaat agttttactt
     8461 acaagacata ttgaggtaga tattaaagtt ttaattttaa ttttattaac tttgtttagt
     8521 ataaatgtat ttatttcata tcttaaaatt aagttgtatg aggataaaat taatttagga
     8581 ttgataaata attcagataa gtttataaat attactaaag atgagaactt cctaaaacat
     8641 gttcaaaatt atattatcag taatgaaaaa gaaaactgtg taatggcttg ttttgattta
     8701 tgtagactca aacttataaa tgatatatat ggttatgagc taggggatga agtgttaaat
     8761 aatattttaa gtaacttaaa aaattatttt ggaaaagaag ctatttatgg aaagttaaaa
     8821 agtgatgttt ttgtattaat aataaagctt gaaaataggg aacagaagat tccttattta
     8881 gtaaatctta tcaagaataa aattatgata ttaagtcaga ttgacagttt taaaatggat
     8941 ataaatattg aggcttctat tggaatttat aaatttaaca ataatgaaat tgatataaaa
     9001 aaagctatag ataatgctga tatggcaagg cttaaatcaa aaggactaaa gcacatagag
     9061 tatgtagaat ttgataatgc tatggaagaa gaaatacaat caattatgaa aatagagaga
     9121 gatttattct tggctattaa aaataaagag tttgtaattc actatcaacc taaagttgat
     9181 tcaagtacag gtaacattat aggttcagag gcattgataa gatggttgca cccatcatta
     9241 ggcatggttg gaccaaataa gtttatacct atagctgaaa aaaatggtct gataaacaat
     9301 attggtagat ggctaattca agaagttttt attaccatta acaagtggat ttcagaaggt
     9361 ataaatgtct taccagtctc aataaatctt tctagagtag aactatataa aaatgattta
     9421 gttgattttt ttaaactgat gtttaataca tataatattc caaaagaact tatagaatta
     9481 gaaattacag aaacgacagc gctaagagat gtaaaattta taagtgaaag gctttatgag
     9541 attaaatctt taggtatgaa tatatcatta gatgattttg gagtaggtaa ttcaaatttt
     9601 atcaatctta aggggatacc actagatatt ataaaaattg ataggtcact tatattggat
     9661 atagttacaa atacaaaaac aaagtttatg gtgaaagcaa ttattaacct ttcacatgat
     9721 ttaaacgtaa ctgttatatg tgaaggggta gaggatatgc atcaggtcaa agtcttaagt
     9781 gaactgggat gtaatttcat acaaggttat gtatttttta aacctttgga tgagatgaat
     9841 tataaaaaac ttcttactga cggaagttat ataaatctga aagatactct tttagataaa
     9901 tgcatgacag ttgaggagga gtaaggatga tttcagaaga tgtagattat tcaataagaa
     9961 tcataagagc tatatttaat aatggagaag ataaaccaat agatgctaaa atgatattaa
    10021 aaagtgaaga tataccaata ctaacactat acagactgct tagaaagctt tgtgcaaaca
    10081 atattcttac ttttaacaaa gaagatggca agacatacat gttaaatgtg tcattggata
    10141 caataagtct aagaactatt gtagaagtaa ttgatggaaa aatatatata aataaatgta
    10201 cgagatatgt atctaattgc agtaattgct taaaaggttg taaagtaaat cgtgaattgc
    10261 tagaaataga aaaagaaatt tataaacttt tatcgagaaa atctataaga caaatactag
    10321 aataaaaaat tttcagctat gataataatt ggaggttttc ggttatggat gatatatctc
    10381 aagataattt tctactgtct aaagagtatg agaatagctt agatgtagat actaaaaaag
    10441 caagtggaat atattatact cctaaaataa ttgtagatta tattgtaaaa aaaactttaa
    10501 aaaatcacga tataattaaa aatccatatc cacgaatact tgatatttcc tgtgggtgtg
    10561 gaaattttct tttagaagta tatgatattt tatatgactt atttgaggaa aatatatatg
    10621 aattgaaaaa gaagtatgat gaaaattatt ggactgttga taacatacac cgtcatatat
    10681 taaactattg tatatatggt gctgatattg atgaaaaagc tataagtata ttaaaagata
    10741 gcttaacaaa taaaaaggta gtaaatgatt tagatgaatc tgatataaag attaatctat
    10801 tttgttgtga tagtcttaaa aagaaatggc gatataagtt tgattacata gtgggtaatc
    10861 caccctatat tggtcataaa aaacttgaaa agaaatataa aaaatttctc ctagaaaaat
    10921 atagtgaagt ttataaggat aaagctgact tatatttttg tttttataaa aaaattatag
    10981 atattttaaa gcaaggaggg gttggcagtg ttataactcc aagatatttc ttagaaagtc
    11041 tatcaggtaa agatttaaga gaatatatta aatcaaatgt caatgttcaa gaaatagtgg
    11101 attttttagg tgcaaatata tttaaaaaca taggggtatc tagttgtatt ctaacttttg
    11161 ataagaaaaa aacaaaagag acatatatag atgtatttaa aatcaaaaat gaggatatat
    11221 gtataaataa atttgaaaca ttggaagaac ttctaaagag tagcaaattt gaacatttta
    11281 atataaatca gagattgcta tctgacgaat ggatacttgt aaataaagat gatgaaactt
    11341 tttataataa gatacaagaa aaatgtaaat atagcttgga agatatagca ataagttttc
    11401 aaggaataat tacagggtgt gataaagcgt ttattttaag taaagatgat gtaaagttga
    11461 accttgtaga tgataaattt ttaaaatgtt ggataaaaag taagaatata aataaatata
    11521 tagtagataa aagtgaatat aggctaatat actcaaatga tatagataat gagaatacaa
    11581 ataaaaagat actagatgaa attatagggc tatataaaac aaaattagaa aacagaagag
    11641 aatgtaaaag tggaataagg aaatggtatg aacttcaatg gggtagagaa aagcttttct
    11701 ttgaaagaaa aaagataatg tatccttata aatcaaatga aaatagattt gctatagatt
    11761 atgataacaa tttttcaagt gcagatgtat attctttttt tataaaagaa gagtatttag
    11821 ataaattttc atatgaatat ctagttggaa ttttaaattc cagtgtttat gataaatact
    11881 ttaaaataac tgctaaaaaa atgagtaaaa atatatatga ttactatcct aataaggtta
    11941 tgaagataag gatttttagg gataataatt atgaagagat agagaattta tcaaagcaaa
    12001 taatatcaat tttattaaat aagtctatag ataaaggaaa agtagaaaaa ttgcagataa
    12061 aaatggataa cttgataatg gattctttag gtatataagc agttgtaagt attaaaaaat
    12121 tataatcctt taattgttta tttaaattta gaaataaaaa gttagccata taaaaaatat
    12181 taaaaatata tacttttcaa tatttttttg ataaaataag aatgaatttg tgcaatttta
    12241 tttttctcca ataactaaaa atagtttttt gaattaatat ttgcttaaga ataaaaatca
    12301 gaaacgtttt tgatatagta ggtgataata tgaaaggatt agttttagaa ggtggaggaa
    12361 caaaaggagc ctaccaaata ggtgcatata aagctttaag agagcttggt atagagtttc
    12421 aaggagtaac tggcacatca attggtgctt taaatggagc atatataatt caaaatgata
    12481 ttgaagtaat ggaagatatt tggttaaatt atgactatac tcattttatg aatattgata
    12541 gagaaaccta tgagaggttt aaaaatgtag atttcactac taaaaatctc aatgcagtgt
    12601 ttgagcttat aaataaagct agaaaaaatg aaggtataga tataagccca ttaagacaac
    12661 taatggagac aacattaaat gaagacataa taaggaaatc aaaaaaagac tttggacttg
    12721 ttacggtctg gtgggataaa aaaattaatc catatccatt gtatatcgaa gatataccta
    12781 aaggaagatt gattgattat ttaattgcta gttccagttt gcctattttt caaacgaaca
    12841 tgatggatga taagttgtat cttgatggaa tgttttgtga taacatgcca ataggactct
    12901 tggaagacaa aggttatgaa gatgttgttg taattaggtt gattgatgat tttattggga
    12961 aaatgaatct aaatcgacat caaaatataa atataaaaac tataatacca tcagaatatc
    13021 taggaggttc tcttaataaa gatagagata atgtagaaaa aaacatccga ctaggttact
    13081 tagatactat gaaagcatat gaaagatgca ctggaattaa gtattatttt gatgtagagt
    13141 ataaatataa tgaagaatat tgttttgata aatttagaag tatgagcaat gaaacaatac
    13201 aatatatctg taatttattg aatataaaaa gagatgcttc acttagaact gttatggaaa
    13261 gtgtaatacc aaagcttggt gaggtgcttg gattgccaaa ggacttttca tataaagatt
    13321 tgttttactg tatatatgaa aagaaacttg aagaaaataa tataaacagg ataaaattat
    13381 atgattttaa caaggttata gatgttgtaa atacaaatat tgattctaat agaaatttag
    13441 cttctaattt tgaagttaga cctaaaatta gtattaaaaa gaacaaaaac acaaaattat
    13501 tgacaaattg tattataaaa gacataaaaa atcaaagtta aataaaaaac aaaaaaaaat
    13561 ttgtaattat actcgaaaaa agtgtatatt agtagtataa tatttttgta gcactagtgg
    13621 gaacaaaaaa tgaccatagg acaaaaaagt accacttagt accattaaag taaaaaacag
    13681 gaaaacaatt ttaaaaaata taaaatgtaa agtttatagg aggatttaaa aaatggaaaa
    13741 agtagttagt atcaaaaatg caagtggatt acatgctaga ccagcaggaa tgtttgttaa
    13801 gaaggcagct gaatttaaat caacagtaga ggttgtagca aaagacaaaa ctgtaaatgc
    13861 aaaatcaata atgggaataa tgagtttagg tttagctcaa ggagaagaat taaagttagt
    13921 tgtaaatgga gaagatgaag aagtagcttt agctgcaatg gttgaattag ttgaaagtgg
    13981 atttggagaa tagatataat aattttttaa aatttgatat ttagaatcta atattactta
    14041 aagtaaagta acagagaagt attaaacata tacagaccaa catttgtaga tatttaattt
    14101 ctttgttact ttcatgttta tttaatcaga agattaagac tattgttaat tgggtataaa
    14161 aatataaata ttttagaaaa tgaaataaga tatttttaat cataaattca gagtaaaaat
    14221 acagtaacaa acagtttata aaatttaata aaaaattata agtaaataaa actataaaaa
    14281 tgtaaattat ttatataaat ttatagagtt tatgtgctag atgatatttt ttaggaggta
    14341 gggttatggc ttacaaagga ataggtgctt ctcctggtgt tgctttaggg aaagcgttag
    14401 tagttgaaca tagtgaatta gtaattgaaa aaaaatctat agataatgtt gaagctgaaa
    14461 ttgctaaatt agaagatgca gttgcagttt ctaaagaaga attagtaaaa gttaaggaaa
    14521 aggcttctga agaattagga gcagaggaag cagaaatatt tgaagcacat ttattagttt
    14581 tagaagaccc agagttaatt ggttctgcaa tagataaaat taaaactgaa agtgtaaatg
    14641 cagagtatgc tttaaatgaa ataaaagaga tgtttgttag catgtttgag tctatggaca
    14701 atgagtacat gaaagaaaga gcggcagata taaaagatgt tacaaataga atacttagac
    14761 atatattagg aattaaagtt gttgatttat ctgctttaag cgaagaagtt gtattaatag
    14821 cacatgattt aactccatca gacacagcaa ctatgaataa aaaaatggtt ttaggatttt
    14881 taactgatat aggtggaaga acttctcata ctgctatcat gtctagaact ttagaaatag
    14941 ctgcaatcgt tggattaaat gatataactt caaaagttaa ggatggagat tttgtagttt
    15001 tcaatggaga cacaggtgaa gtaattgtga atcctgatga agagactata aataaatata
    15061 ctgaattaaa agctaagtat gaagatgaga gaaaagcatt acagctatta aaaggaaaac
    15121 catctgtaac tttagatgga aaacatgtgg aattagctgg taacatagga acacctaacg
    15181 atatagaagg tctaataaag aatgatgctg aaggtgttgg tctttataga acagaatttt
    15241 tatacatgga tagagattct ttcccaacag aagaaataca atatgaagca tacaaagctg
    15301 tattagaagg aatggatgga aagccgatag ttataagaac attggatata ggtggagata
    15361 aagaattaag ttatttaagt atggaacctg aaatgaatcc attcttaggt tacagagcaa
    15421 taagactttg cctagataga aaagatatat ttaagactca attgagagct ttatatagag
    15481 ctagtattca tggaagatta agaatcatgt tcccaatgat ttcatcttta gaagaattgt
    15541 tacaagctaa agaagttgta aaagaagttt tagcagaact tgattctgaa ggtgtggctt
    15601 atgctaaaga tgtagaaatt ggtatgatga tagaagttcc atctgctgct gtaatatctg
    15661 atgtattggc taaacacgta gatttcttct ctataggaac taatgattta attcaataca
    15721 cttgtgcagt tgatagaatg aatcaaaaga taagttatct ttacaatcaa tttaatccag
    15781 ctgttttaag acttataaag actgttatag acaatgcaca taaagaagga aaatgggcag
    15841 gtatgtgtgg agaatctgcc ggagaccaaa aaatgatacc aatactttta ggtatgggat
    15901 tagacgagtt ctctatgtct ccaatatcaa tacttcctgc tagaaagtta ataacttcag
    15961 ttaaagagtc agatatgaaa aaattagctg atgatgtact taatatgggt actgctgaag
    16021 aaataaaaag ctatatagaa aagactttta atatataatt aatgttatat agttactaaa
    16081 attcattttt ctaaataaca aaattatatt ttacgaatta aaaaggagat gtttcaaaat
    16141 aaaaatttga agcatctctt ttttataaaa gattactaag aattacttaa tctttgtaat
    16201 agtcattttg tgaaaaagca aaactgcatt gtgactatag tatatatgga tgttattatc
    16261 aataaaagta ctattaaaat gaagattcat tctcaaatga tatcaaaagt agttgtgatg
    16321 gagtaagata atattttgtg atttaatagt aaaaattaaa aaaatatggt attgaaaaat
    16381 aattaaaagt atttaataat agaattaggg aagaataagt ttataagtaa aaataattga
    16441 ttactagtta ataaaataaa tgtgatatcc aaataaatcc taaatctaat ttgagtttta
    16501 atatagatag tctaaagttt gattattaaa gatttaattg taagttgtta cagttgatga
    16561 tattgattag agattaaagt ttagagtaga aagttacctt aaatttaaaa atgcaagata
    16621 acccaatcta aaaattataa tcactcgata ggtttaagga tttatttgtt tattataaat
    16681 aggagggtgt ctcaaaatga actttttagt ttatgaggca ctctctttta tatagaatta
    16741 aatatatttt attatttcaa caatgaaaaa gaagcttatc tctattttga gacagcctct
    16801 ttgtatacta ttattaattt aattaataat ataatttaaa attataatat tagttaagat
    16861 ttcctgcttt attagtaaat aattctttaa tagcattgtt tctggaaact aaatcgttat
    16921 cagagttgtt tgtttttttc ataatcactg aataacgttt tttatttata aaaaatatta
    16981 aaatcttatc atcatcaaaa ttgtattctt tatatctgtc aatagactca taacctagat
    17041 ttagaatgtt tttgtctttt atactatcta catctaaaat atatgatggg tcagccttta
    17101 gtaatatatt aattaaacat ttttcttcac cagcacagaa taactccatc ttacttgata
    17161 tagatttaga ttgctctgaa gttatttttg caggaataag gttgtcatta tcatctctta
    17221 gaagataacc atgtgtgtct tgttgatata ctaaattaac ctttttctta ggaacactaa
    17281 tcattttatc taaatgtaca taatgatgat tttcaacaaa accttcattt aatatttcaa
    17341 caaagttatt aattttacct aggcaaaaag attctataga ttctttacag aatttatttg
    17401 taaatggtat tatgtttacg ttttcctcat ctgtattcca tgctatagca taatccaacg
    17461 aatatacttc ttcctctata tctgcaaaat tatattgtac tatgtttcct ttcaaaatta
    17521 ctcgacctcc atcttataat atatttaata tactttataa aacttatatt atatttaaat
    17581 aatatcataa attggataaa tatgatatag taaataagaa aaaatttgaa aaaaatcact
    17641 ataaatgagt aataaatata aatagtgtat actaatggga tggaaaatgt ccactattaa
    17701 ctttattacc ccacatatat aagataaaat tattaatata aaatataatc tatcgacaat
    17761 gaatagactt ttaaataaac ttaatataaa attaattaaa taagtgctta aaaacgattt
    17821 actttaatga tagaatcata ttaaaggagg ataattttat ggatataaag aataaaatta
    17881 aatctatatt tttaccagaa aaaaatgact atttagatga tgaagaattt gagtatgata
    17941 tagaaaataa tgaagaagat ttaaaggaag ataacaaagt acatttaaat gatttaagca
    18001 gagtaaaata tgattacaga gagttaaaag acatagaaaa ccaaacagaa gagatgtgtc
    18061 tgctagcagt aaagcaggat ggtactataa ttgagtttgt aaaggacaag acttataaag
    18121 tatgtatgga agcagtaaaa cagacatata aagctcttaa gtatataaca aatcaaaatg
    18181 aggatatttg tatagaagca gtaaaacaga actacagagc tttgtactac ataaataata
    18241 agacagaaaa tgtactaatt gaggctataa aaaatgcatc aacttatgat gtcatggaag
    18301 tatttaaatt tgtggaagat caaacagaag atgtatgtct agcatttata gaaagggcat
    18361 ctaaaaatga tgttgcagag atattaaaag gaataaaaga gcaaactcca gccatatgtt
    18421 tagaagctgt aaaaaaagat ggaaaatctt tagcttatgt aaaggaacaa agtaatagta
    18481 tatgtttaga agctgtaaaa gaaaactaca gtgcactatc ttgtgtaaaa gagcaaacag
    18541 aagaaatatg tatagaagca gtaaaacaga atgactttgc attgtattat gtaaatgaac
    18601 agacagaaaa aatatgtatg gaagcagtaa aaagaagtta tatggctcta cagtatgtaa
    18661 ataagcaaac agaagagatt tgtttggaag cagtaagaat tgatggaaga gcattacagt
    18721 acgtaaaaga gcaaacagaa gaaatttgct tggagtcagt tagacaaaat ggaaaagtat
    18781 tgcaatatgt aaaaaaacag actgaaaata tatgtataga agcagtaaga ggttcatttg
    18841 aagaacttga aataaaagaa atattaagtt atgtaaagat accaacagaa agaatatttg
    18901 tagaagcagt aaagcaaaat ggaaaaattc ttaaatatgt agaaaatcag acagaattaa
    18961 tatgtttaga ggcagtaaga gaaaactata atgctttagc ttatgtaaag gaacaaacag
    19021 aagagatttg tttagaagca gttaatcaaa gttatgaagc gcttaaatat gtgaaagaac
    19081 aaacagaaga agtttgtcta aaagcagtaa aacaagatta tagaatgttg aaatatgtaa
    19141 ataatcaaac agaaaaaata tgtttagaag cagtaaagca aaattataga gctttagaat
    19201 ttgttgataa tcaaacagaa aaagtttgtc ttgaagcagt aaaacagaat agaaaagcac
    19261 tacagtatgt aaaacaaaaa caaagttaaa aggctaaaat atatagaaaa tatatgcaaa
    19321 taaataaaat ttgatatttt gtaataaata aaatgggtat ctcaaaatga actttttagt
    19381 ttgtgaggta ctctttttat atgaaataaa atatattttt agccttttaa caatggggaa
    19441 aaggtttatt tctattttga cataggcttt ttatgcatat aaagcttgat aaaattgttt
    19501 tattataatt gttttgttat ataaataata ataagaaaat tatataggtc tttttttgac
    19561 cagttttgca tttttaacaa ctagttttgt aaagtatatt gaattttctc aaaaaagaat
    19621 gtactctata tatgtaaaat ttttttggag gtaaaaatgt ttaaaagata tgctgaaaaa
    19681 atgacatctg ttttaatttg taataatatg atagataata atgaatctaa agtctattct
    19741 tatggatttg aaatattaat agctttcata gttaatataa ccaccatgct gtttataggt
    19801 tttttatttg gtaaatttac atatgtatta ttttttttaa tgtgttattg tccaataaga
    19861 caattttcag gagggtatca tgcagacaat tattttagat gcttattaac ctttattttt
    19921 ataattttat ctacaatctt aattatagaa aatataaata tagacttatt taaaaatatt
    19981 attatgatta ttgcaagtgt tagttgggtt ggaatttgtg ttctgtgtcc aatagaacat
    20041 aggagtaacc ctataagtga tagggaaaag tttgtttata agaaaactgc tatatttata
    20101 tctacagtag tgttattgat aacaatttta agtctttctt tgagtatatt tgtagattat
    20161 ttcacatata gcgcatttgc catgttttgg atttttgtga tgttagtatt aggtaagtta
    20221 aaagctaaag tataagtaaa atatgtatga gggagagtta agttatgaaa aagtttattg
    20281 taagatttat gaagtttgct agctcattgg cacttagcac tgctattttg tcagctaata
    20341 gtacctgtcc ttggattatt catcagccta aagtacccaa agaaatcagc aatctaaaga
    20401 agacaaatta aatacaagca cttatttata caaaattatc aggaaaaaag aaattattat
    20461 attttaataa gattaaaaca atataaaatc agatacaaaa tttattttat ttattttata
    20521 ggagcctaat acctatttgg taatatatta gtgcgccaat ttagggggat atagtgtatt
    20581 taatgaaatg acttacggag agtaagtcat ttttgtattg tatgtatttt atgtaaactt
    20641 atgatataat gaagggtaaa gtttaattaa aataataaaa aactttagta tagatagtaa
    20701 tttaggaggt agggtatgag tatgatacat aaattttcta tgaatggata taatatcgtt
    20761 ttagatgtga atggtggagc tgttcatgtg ttagatgatg ttgcatacga tttgttagat
    20821 ttttataaag aaaaaagtaa agaagaaata ttagagatat taaaatcaaa atatcaagaa
    20881 gaaaaaataa atgaagcata tgaagaaata ttaaatttgg aaaaagaagg tcttttatac
    20941 acagaagata catatcaata tcatccaagc tttgtacata gagagcctgt agtaaaagct
    21001 ttatgtttaa atgtagctca tgattgtaac ttaaaatgta aatactgttt tgcagctcaa
    21061 ggtgattttg gaggagaaaa agaacttatg agttttgaag ttggtaaggc agcaattgac
    21121 tatttgattg ctaattcagg aagtagaaag aacctagaga tagatttctt tggtggagag
    21181 cctttgatga actttgaagt tgtaaaacaa ctggttgact atggaagaag tgtagaaaaa
    21241 gattataata aaaatataag atttacaata actacaaatg gtgtactgtt aaatgatgag
    21301 attatagatt atataaatga aaatatgcat aatgtagttt taagtttaga tggaagaaaa
    21361 gaagttaatg ataatatgag accaacttta aatgataaag gaagttatga tattacatta
    21421 ccacgattta agaaacttgt ggaaaaaaga gcaaaagata agtattatta tataagaggt
    21481 acttttacaa gagataattt agatttttca aaagatgtta tgcattttgc agatttagga
    21541 tttaaattaa cctctgtaga gccagtcgtt ggagatgaga gtaatccata tgcacttaga
    21601 gaagaagatt tacctaagat atttgaagag tacgaaaaat ttgctgtaga gtatgcagat
    21661 agacaattac aaggagatgg atttaaattt ttccatttta tgatagacct aaatcaaggt
    21721 ccatgtgtaa taaagagaat aactggatgt ggagctggaa atgagtatct ttctgtaact
    21781 ccaaatggag atatctatcc atgtcatcaa tttgttggaa atgaagaatt taaaatggca
    21841 aatatatttg atgaagaaat agtacttcca gaaaatttaa aaaatatgtt tagagaagct
    21901 catgtatata ctaaagaaga gtgtaaacaa tgttggaata agttttactg ttcaggtgga
    21961 tgtcatgcaa atgcgataaa ctttaataat gacatatcaa aaccatatga attaggatgt
    22021 gaaatgcaaa gaaaacgtac agagtgctct ataatgatac aagctaagtt aatgttagaa
    22081 ggagcaacca actaaattta tattttaaag gagttgttta tatatgatta gagattattt
    22141 agaagataaa cctttaattg acgaaagtgt atttgtggca aaatcagcag atgtaattgg
    22201 aaatgttaaa ataggcaaag attcaagtat atggtacaat gcagtagtta ggggtgatga
    22261 aggaccaata actattggag aaaacactaa tatacaagat tgttctatag tgcatggaga
    22321 tacagaaact ataattggta acaatgtaac agttgggcat aggtctatag ttcatggttg
    22381 taaaattagt gataatgtgt taattggtat gggttcaata atattggata atgctgaaat
    22441 aggagaatat actctgatag gagcaggtac actaattaca tctaataaga agtttccacc
    22501 aggtgttttg ataatgggtt ctcctggtaa ggttgttaga gagcttacag aagaagataa
    22561 aaaatatatt gatgaatctt atgaatggta tttagaggca gcacaaaatc aaaaatatta
    22621 gtttaaagag tggttgtttc aaaacatatt taaatctgtt ttgaggcaac cactaattta
    22681 ttttattaga ttttgttgat attttagttt tcaaaaagta tttgattaaa ccagatataa
    22741 aatgtcaaaa ataaaaatta actgagttaa ataattttaa taaaattggt agtatatgtg
    22801 ataaaattaa atattaaaga ggatatagga tattagaata tcaattggtg aaataatgtc
    22861 atatacgata aattaaggtg taagtttttg ggtataccta tcttaggagt gaaaagattt
    22921 gagaataagt tatagaaatt taaagcgata tagagaaatt ggatatgttt taataaagta
    22981 tggttttagt tttattgtag aaagactaaa tatagaagga attgcctata aaataccact
    23041 atttgaccca ccagaagaaa taaaaaatat gacaactggt gagagaatga aaagagtttt
    23101 agaagaacta ggacctacat atataaaaat aggacagata ttgagtacaa gaaaagactt
    23161 gttagaccag gatataattg atgaaatatc aaaactcaga gatgatgtag agaaatttga
    23221 ttcaaatata gctattgata tatttaaaga agaagtgggt ttaagtatag aagaaatatt
    23281 cttagaattt aaagaagaac caatagcagc agcttcaatt ggtcaagttt atgaaggtgt
    23341 acttaaaacg ggagaagaag taatcgtaaa aattcaaaga ccaaatatag agaaaataat
    23401 aaaatctgat ttagagattc ttagaactat tgcaaatact ttaaaagatt taaaaaagga
    23461 ttttaattta gatttagtac agatgattga agaatttcaa actcaattaa tgagggaact
    23521 tgattataca tttgaagcca taaatgcaac taaattctct aggatattta aaaatagtga
    23581 tgaagtatat atacctaaag tatactcaga atataatact aagaaaattt tagtaatgga
    23641 gaaagttaat ggtacaaagt taagtgatgt agaaaaaata aggagactag gttataacac
    23701 aaaaactatt gttgaaatag gagttaggtc attttttaca caggtattat ctcatggatt
    23761 ttttcatgca gacccacatc caggtaatat atttgtagtt gctaaaaata agatagcata
    23821 tatagatttt ggaatgattg gaattattga taataaaact ttaaaccaat taaatgaaat
    23881 tgcattagca ggtgtagaaa agaatgttga caagataata tatctattga tagaaatgga
    23941 tgcattaaat ggagaggctg atattaaggg acttagacag gatttacttt atctaataca
    24001 ttattactat gatatttcta tagaaaaaat aaatgtaaca gatatattaa atgaactatt
    24061 taggtttttt agacagtata aaatagtcat gcctgcacaa tttgtaactc ttgcaaagac
    24121 agttataaca ttagaaggaa caagtagaac tttaaacaca gatttttctt ttggttctat
    24181 gggaaaagag tttatgaaac atcattataa gagtaaattt aaccctaaaa atgttgtttt
    24241 aagttcaaga caaaatgtag aagaaatatt actggacata aaaactattc caaagcaatt
    24301 aaaagcaatt ttaaaaaata tagaaagaaa taatataaaa atgcaaattg aagatgttaa
    24361 aatgacgagg ttagaaaatt gtataataga gctaacatct caaatatctt tgagtttagt
    24421 gttggcatct attatagtag gttcttctct tataattgca tctccaaata tagaaaataa
    24481 tatatggata aaatttactg caatagcggg tttctttata tcctttataa taggcctttg
    24541 cttagttata agaagtatta ggtcaaaata caaaaaagat tagggggaat taaatttgaa
    24601 aaaatggata ttgaagtata aaggtaagat agaggaaagt gaatttagca aaaaacttaa
    24661 tatttccccg gaaatctgcc aaattttaaa aaatagaggg atatgtactg aaaaagattc
    24721 agaaatattt atgaatccat ctttagatta tttaagagac ccttttttaa tgaaagatat
    24781 gcaaaaagct gttgatagaa taaagttagc agttgagaag aacgaaaaaa tttggattta
    24841 cggagattat gatgttgatg gtgtatcatc tacatccatc ttgtgtttat attttaagag
    24901 tataggttac aatgttgatt actatattcc taatagatta gaagaagggt atggtataaa
    24961 tgaggatgct attaagctta taagctctag gggatgtgac ttgattataa gtgttgactg
    25021 tggaattaca tcagtgtctg aggtcaatac agcgaatgat ttgggcatag atgttataat
    25081 tacagaccat catgaatgtc aaagtgaaat tccatcagcc tttgcagtaa taaatccaaa
    25141 acaagaagat tgtaattatc catttgattc actatgtgga tgtggtgtag catttaaaat
    25201 gattcaagcc ttgactccaa aagaagaatt taaaactagt atgtataatt atttggaaat
    25261 agtaacacta gcaactattt gtgatattgt tccacttata gatgaaaata gaataattgt
    25321 aaaaaatggt ttaaaatcaa tgaaagaagg caaaaatatt ggattaaggg agcttataaa
    25381 agtttgtggt gtagaaagtg ataagatagg ttcttctcat ataggttttg caataggtcc
    25441 taggataaat gcttcaggtc gattgggata ttcttactta ggagtagagc tatttactac
    25501 tcagtcacaa gaagaggcag tagaaatagc tagtatattg gaagaaaaaa ataatgaaag
    25561 acagatgata gaagctaaga tgtatcatga agctgaagaa atgctaaagt ctaatagcag
    25621 atacaatgat gacaaagtgt tggttttagc caaagagggt tggcaacatg gaataatagg
    25681 aattgtagca tcaaagttaa ctgaaaaata ctacaaacca acaattcttc taggtataga
    25741 aaatggggag gctactggtt cagcgaggtc aataaaagga tttaatatat ttgaagctct
    25801 cataaagtgc aaagacttga tgactaagtt tggtggtcat gaacaagcag cagggttatc
    25861 cttggattca gacaatgtag aaattttagc aaatgaaata aataaatttg cagattataa
    25921 tttaactgaa gatgatatga tagagaatgt aaatgtcgag tttgaattac aagaaaatgt
    25981 aataaattta aatcttgtag aagaattaca taagttagaa ccctttggat taaataatcc
    26041 taatcctaga tttatagtta gaaattatat tttaaaagat ttgaaagtta taggtaagaa
    26101 tcaacaacat ctgaaattaa gtatagaaaa agagaaaagc tatgaatgta taggatttaa
    26161 tatgagtcat ttaaaatcaa tgtataaagt aggagacaaa gtagatgtac tattccaatt
    26221 agatgaaaat aactatatgg gaaataggaa agtacaattt ttacttaaag atatacgatt
    26281 ggctcgacct aaaagtgcaa gtaatgacaa actttcattg aaattaatgt caaaaataat
    26341 accaaaagat actcaaagcc tgtataatat atctgtgtct gattttgaat tatttgatgg
    26401 aaatacagat ataaatatat ttgattattt tgaaaaagat acactaataa tatctaattc
    26461 tataaatgga ttttatagag caatgtcaga tatatcactt atagatttgg attttaacat
    26521 aaattacaat attattgaag atgttagcaa aaatactgat aaattagagc ttatattttc
    26581 tcctaatatt gataaaatag acttaaaaag atataataat attattcttt atgattattt
    26641 atacaataaa ggcgaatatt cgtatatata tgagaataaa agagaagaaa gtgaaattat
    26701 aaaatattat aataaaacag acctattata tttaaagaat gtagttagta atatagttcc
    26761 atcaagagat gaatttataa caatttataa acaagcactt ataaaaaaag aaattgattt
    26821 ggatatggta aatataaggg aaacttttaa tgtaattcca ttaaagtttt ttacgatatt
    26881 aaatgtattt agagaattaa atttacttga ctttaattta aattatgaaa aaaattctgt
    26941 actcataaga atattgccaa aaccacagaa aaaattagac ttaaatgaga gtttaatact
    27001 caataatcta aaaaatttag aaaaacaata caatagcagt tattaggagg cgtttcccat
    27061 ggatttaaaa aactttataa ggaatattga tgatttccca aaaccaggca tagattttaa
    27121 agatgtgaca actctattta aagatggaga tgcatttaaa tatgcagtgg attctatagt
    27181 tgaagaattg aaagataaag atgtagattt agtaataggg ccagaagcaa gaggattttt
    27241 gatgggtaca cctgtagcat atgctttagg agtaggattt gttccaatta gaaaacctgg
    27301 aaagttacca ggtgaagttg agagttatga gtatggatta gagtatggta cagatacttt
    27361 agagatacat aaggatgcaa ttaaaaaggg tcaaaaagta gcaatagtag atgatttatt
    27421 ggctactggt gggactatgg aagccgctgc caagcttgta gaaaaattag gtggagaagt
    27481 agtttctatg caatttttga ttgagctaaa attcttaaat gggagagaaa agttgtctaa
    27541 ctatgatgtt aattctctta taaaatacta gtacttttat aatagttggt ataacaccaa
    27601 ctattttcat atatattaaa attttataca aaataggtgg ttatatgcat gataaagaat
    27661 tacaagaaat aattgaaaaa ataaaagttt atgcacctaa tgcaaatttt gaaatggttg
    27721 aaaaagccta taatcttgca aaaaaagcgc atgaaggaca atatagaaaa tctggggaac
    27781 catactttat tcatccatta gcagttgcaa atattttaat agagatggaa ttagatattg
    27841 aaactataac agcaggttta cttcatgatg ttgtagaaga tacagaatat acctatgaag
    27901 acataaaaaa agaatttggc aaagaagtag cggatttggt tgatggagta actaaacttg
    27961 gtcaaataaa atatcgttcg aaagaagaaa ctcaatctga aaatttaaga aaaatgtttt
    28021 tggcaatggc gaaggatata agggttatac ttataaaact tgctgataga ttgcacaaca
    28081 tgagaacatt aaaatacatg cctccagaaa aagcaaagta taaagcaaaa gagacacttg
    28141 aaatttatgg tggtatagct catagattag gaatttccaa gataaagtgg gaactagaag
    28201 acagagcatt aagatttatg gacccagaag ggtattatga tttagttagt agagtatcaa
    28261 tgaagagaag tcaaagagag gattatattc aaggaattgt tgaacttctt aaagataagt
    28321 ttaaagattt aagtatacca tgtgatgtat atggtagacc aaagcatttt tacagtatat
    28381 atagaaagat gcaaaaaaaa cataagactt ttgaagagat ttttgattta acagcagtaa
    28441 ggatattggt tgataatgta aaggattgct atgcagtact tggtatagtt catacattat
    28501 ggagacctat tccaggaaga tttaaagatt atatagcaat gccaaaaccc aatatgtatc
    28561 aatcattaca caccactgtt gtaggtcctg atggagaacc tttagagata caaataagaa
    28621 ctcatgagat gcataatata gctgaaaatg gtatagcagc ccattggaaa tataaagaag
    28681 gtatctctag caaagagtca aaggttgaag aaaaacttca atggttgaga cagatgatgg
    28741 agtgggaaaa agatttaaaa gacccacaag agtttatgga tgcacttaaa gaagatgtat
    28801 ttaatagtca agtttatgta tttacgccaa aaggagacgt aattgaatta ccagcagaat
    28861 caacacctat agattttgcc tatagagttc atacaaatgt aggtaataaa tgtgtaggag
    28921 ctaaaattga tggaagaata gttcctattg attataagct tcaaaatggt aatattgtcg
    28981 aggtacttac atcatctaat tctaatggac caagtaggga ttggcttaat atagtgaaga
    29041 ccccaaatgc aaaaagtaga attagacaat ttttcaagaa ggaaagaaga gaagaaaatg
    29101 ttgaccgtgg aaatacaata ttagaaagag aatttaagaa gcatgatata ccacaaaaag
    29161 accctcttgt tgaaaaatat atggcattag ttgctaagaa atttaatcag ccaagtgttg
    29221 aggacttaat tgccactgta ggttatggcg gtataatgtc atctcaagtg gtatctaagg
    29281 taaaagacct atatttaaaa gaggttaaaa aagctaaaaa ggaacaacag atacaagaag
    29341 aagatttaaa taaacacaat ataagtgaaa cagaatacag taaaaagaga aagaaaaacg
    29401 catcacaagg aattatagta aaagggcttg acaatatctt agtaagattt gctaagtgtt
    29461 gtaatcctct tccaggagat gaaattgtag gatatattac taagggtagg ggagtagcca
    29521 tacacagagc tgattgccca aatgcaaaca ataatggtga tttcttccaa aatagattgg
    29581 tggaggtttc atggagttca gcaggaaaag gtaagtttga agcggaaatt caaataaaag
    29641 ctattgacag aagaggaatt gttaatgaaa taactcatat tgttgcaatg gataaactta
    29701 gtttaaacgg aataaatgca agaaaaggta aggatagtat tgtaagtata aacttacttg
    29761 tagaggttaa tgacacagag gaattaaaaa ttctaatgaa aaaattaaaa gcaattcctg
    29821 gtgtagaaag tatttataga atgacaaatt agagttaaaa taatagggag gaaactatga
    29881 gagcagtagt gcaaagagta tcttcatcta aagttacagt agatgaaaac actataggtc
    29941 aaataaataa ggggttacta gtattgttag gagtgactca tgatgataaa tcaagtgatg
    30001 tagattatat gattgataaa atattgaatc tgagaatttt tgaagatgaa aatgacaaga
    30061 tgaatttatc tctaatggat ataggtggag agcttttagt agtatctcaa tttactttat
    30121 atggagattg cagaaaagga agaagacctg gatttagtaa tgcatctaga ccagaacttg
    30181 caaataacct ttatgaagaa tttgtaaaaa aagcaaaaga taaaggtgtg acagttggta
    30241 caggtcaatt tgcagctcat atgatggtag agttaactaa tgatggtcca gtaacaatac
    30301 tattagactc aagtaaatct ttttaagggg gaaaacttta atgattataa aaaaatttgt
    30361 agatagttat tttggagtaa atacttatgt attaggtgat gaaaagacta aaaaatgtgc
    30421 agttatagac ccaggtggaa gtttagtaga gacattaagt tttgtaaaag aaaatgaatt
    30481 aaatattgaa tatattatcc ttactcatgg gcatggagac catataggat atgttaagga
    30541 tattaaagaa aaaactggtg ctaaagtagt tgcacatgtt gatgaaaaag aattattaaa
    30601 tgataaaaat aaaaatctaa gttatacaat gagatgtgga gcgcaagagt ttgatgcaga
    30661 tatctatgtg agtgataaag acaagcttga acttggtgaa ttaaaaatga ctttcttgca
    30721 tactccagga catactcaag gatgtatgtg tataagagtt gaagatgaaa tgttcacagg
    30781 agatactttg tttgctggaa gtattggtag aactgattta tatagtggag actttaacca
    30841 aatggaaaaa tcacttaaga aattatgcaa atatgaagat gctgttagag tatatcctgg
    30901 acatggacca accagtactc taggggttga aaagaagaca aatccttaca tgtaatttta
    30961 tattagtatt taaaaaagta taaaatattt aataactata ttagtgaggg ggttcttcta
    31021 ctgttaaata gaaggagtta agttgatgtt gtatgttttt ttaaaaggac atgattataa
    31081 gtatgaagta gcagaactta taaaattgtt taccagtgaa tttaagttta aagactctaa
    31141 tgctaacaat aatatagagt caaagcattt aataaataga ttgatttatg agaatggtgt
    31201 attattctca agtactgaat actatgaaaa tggaaattta aagtacgagt caatacagaa
    31261 tatagaaaat atgaatcttg aatttttaga tggatttgat agtagcaaaa cgattgaaga
    31321 atttcttaat agactagata gtgaaagtaa gaggaacttt aaaaagctgt gtaaagaaaa
    31381 tatcaaaaaa agcatgtttg tagtgcttaa acaagtattt aattcttatg taccatgggg
    31441 aattttgact ggtattagac cagtcaaaat tgtccacaat ttaatggata aaaagctaga
    31501 tgataatagc ataagaacca ttctaaaaga taattatttt ataatagata agaaaataga
    31561 tttagctctt gaaatagcta aaagagagcg attatttatg tatcctatag ataaaaataa
    31621 aatttctctt tatgtaagta ttccattttg tccaactaga tgtgtatatt gttcatttcc
    31681 ttcaaattca ttaaaacaat ttggacattt aaaaagagaa tatgtttata aattgattga
    31741 agaaattaag gggtttgcca aagttattaa ggagactaag aaagaagttg aaactctata
    31801 tattggtggt ggaactccaa ctacacttga tgaggaagaa ttagatttgc ttataaattc
    31861 attgttcaat gaattagatt taagtaaaat taaagaattt actgtagaag caggtagacc
    31921 tgacactatt acagaacaaa aactaagagt gttaaaaaaa cacaatgtta gtagaattag
    31981 tataaatcct caaactatga atgatgatac cttggtaaag attggaagag agcatagagt
    32041 atctgattta gtagattgct ttaatatggc tcgtagaatg ggatttgata atataaatat
    32101 ggatataatt ttaggtctta tagatgaaga attaaatatg gtaaagaaca cattggagga
    32161 gataaaaaaa ctttctcctg aaagccttac agttcataca ttagccataa agagagcatc
    32221 caacttaaat ataaatatgg ataggtataa agaacatcta acacaatatg aagaaatggt
    32281 aaaaatgata gatttatcaa tgaaatatgc aaaagatatg ggattaaatc catattatat
    32341 gtacagacaa aaacatatgt tgggaaattt agaaaatata ggttatgcta aagaaggata
    32401 tgagtgcatt tataatatac agattatgga agaaaaacaa agtaactatg cattaggtgc
    32461 aggtgctata tcgaaatttg tttatgtaga tgaagataga attgaaagag tagaaaatgt
    32521 aaaaaatgtt gaacaataca ttgaaagagt agatgaaatg ataaaaagga agaaagaaga
    32581 ggtatataaa aatgttgact aaagctccta gaggaactaa agacataact ccaaaagagg
    32641 cttacaaatg gcgttatgta gaaaataaat ttagagaaat atgtgcttta tatggatatg
    32701 aagaaatggt aacacctata tttgaacata cagaactttt caagagaagt gttggagata
    32761 ctacagatat agttcaaaaa gaaatgtatt cttttaaaga taaaggtgat agagaaatta
    32821 ccttaaagcc agaaggtaca gcaggtgtag taagagcatt tatagaaaat aaattatatg
    32881 cagatactca accaacaaaa ttattttatg tgacaccttg ttttagatat gaaagaccac
    32941 aagctggtag acaaagacaa tttcaccaat ttggaataga agcacttgga agtgatactc
    33001 cttcaatgga tgctgaaata atcgcactag ctgttcaatt ttttaatgaa gttggattaa
    33061 atgatttggt agtgagtata aattcagttg gctgtccagt ttgtagaaaa gagtacaatg
    33121 ctttattaaa agagtatctt gactcaaaag ctgatatatt gtgtgatact tgcaatgaga
    33181 gaagagaaaa aaatccaatg agggttatag actgtaaaaa tcctacatgt aaagaaaata
    33241 tcaaagatat accatttatt gcagaccatt tgtgtgatga ttgtaaatct cactttgata
    33301 aacttcaaga atacttaaag gaaatgaata taaactttgt aattgataaa acaatagtta
    33361 gaggcttaga ttactataga aaaactgctt ttgaaattat atctaatgat ataggagctc
    33421 aaagtactgt atgtggtgga ggaagatatg atggtcttgt tgaacaatta ggaggaccaa
    33481 aaggtataag tggaattggg tttggactag gaattgaaag acttttactt acacttgaag
    33541 gtaatggaat tgaaatagaa aaccctcaat ctacggatat atttatagta actataggtg
    33601 aagaagcaaa tacaagaagc tttaaattat taaaagactt gagacaaaat catataagtg
    33661 cagataaaga ccatatagag agaagtgtta aagcacaatt taaatattca gataaaataa
    33721 attcaaaatt tacaatagtg attggagatg atgagcttaa aaatgacact gcgacattaa
    33781 aaaatatgaa aacatcagag caaactactg taaaattaag tacattagtt gaagaattaa
    33841 agcaaaagct gtaaaataag aaagtatgat gttttgtgta ttagataaat atatagcatt
    33901 aaaattaaat aaaatggagg tagtatcttg gaaactttaa agggtttaaa gagaactcac
    33961 tactgtggag agttgagaga aaaaaacata aatgaagaag tcgtacttat gggatgggta
    34021 cagaaaaaaa gaaatttagg tggtcttgta tttgttgatt taagagatac aagtggatta
    34081 tgtcaaatag tttttgatac agatgtagat aaagaagctt ttgaaaaagc tgaaaaatta
    34141 ggggctgaat ttgtaatagc tgtaaaagga aaagtatgcg aaagacaatc taaaaaccct
    34201 aatatgccaa ctggtgatat agaaatattt gcaactgaac ttagactttt aaacaagtca
    34261 gaaactccgc ctatttatat aaaagatgat gatgatgttt ctgaagcact aagattaaaa
    34321 tatagatact tagatttaag aaaaccatct atgcaaagaa atttaaaatt aagacataaa
    34381 gtaatgaata ttacaagaaa ttacttatca aacaatagat tttgcgaaat agaaacacca
    34441 tttttaatag ctccaacacc agaaggagca agagattatc tagtaccaag tagagttaat
    34501 ccaggaaaat tttacgcatt accacaatca ccacaattat ataaacaatt attgatggta
    34561 agtggtatgg ataggtattt ccaaatagtt aaatgcttta gagatgaaga tttaagagca
    34621 gatagacaac cagagtttac acaaatagac tgtgaaatgt cttttgtcga gcaagaagat
    34681 gttatgagta tgattgaagg tttgcttgaa gcgatattta aagaagtttt agatgtagaa
    34741 ttggcacttc cacttcctaa gatgacttat gcagaagcta tgtctaaata tggttcagat
    34801 aaaccagata ctagatttgg atatgagtta acagatatat ctgatgttgt ttgtaactgt
    34861 ggatttaaag tgtttgctga tgctacacaa ccaggaaaaa gtgttagagg tataaacgta
    34921 aaaggcaaag ctgacgactt tactagaaaa caaatatcat cactagaaga acatgctaag
    34981 acatatagag caaaaggtct tgcttggatg aaagtaggac aagaaggagt aacttctcca
    35041 atagcaaaat tctttaatga agaagaaatg aacgctatac ttacaaaaat gaatgctgaa
    35101 gtaggagatt tacttttatt tgtagctgat aaaaactcaa tagtatttga tgctttagga
    35161 caagttagac ttgaagtagc aaataggctt aatctattgg ataaaaatgt atataactta
    35221 ctatgggtaa ctgagttccc agtttttgaa gaagatgaag aaacaggcac attttcagca
    35281 atgcatcacc catttacatc acctatggat gaagatttag acaagttaga agaaggtgat
    35341 aagtcatctt taagagcgaa agcttatgat attgtattga atggttatga aataggtgga
    35401 ggaagtgtta gaatatcaaa ttctgatatt caatcaagaa tgtttaaagc acttggtttc
    35461 acagaggaaa gagctaatga aaagtttggt tatttattag aagcatttaa atatggtact
    35521 cctcctcatg ctggtctagc ttttggtctt gatagacttg ttatgttact tgcaggaact
    35581 gataatataa gagaagttat tgcattccct aaaaatcaaa atgctgtttg ccctatgaca
    35641 aatgctccta cattggcgga agatgagcaa ttagaagaat taagtataaa agttgatata
    35701 aaagataatg aataatatgt agttgcaaga aactaaaatg taaaaagtct ggatataaag
    35761 tatatttata ttcagacttt ttttattaga attattttat attttttctc tatatatttt
    35821 cataaattat ccttgtattc tcagccaata taattaaaat actatgttta aaaattttac
    35881 ataaacttga ttgttttaga aattacttct gtaatgagta cacgatttta attaaagaat
    35941 atataacaaa tttgaaataa gtctaatata tgacttaata gattaaatta aaataataaa
    36001 tttggactat ttatctattt ataacttaaa ttatatcaaa ttgataacaa actagatatt
    36061 atactttttt gtagaataga attacaatta tataaagaaa aattctatta atagtgaaaa
    36121 aaaagtagaa aaaagtagaa attattcttt tataaagaaa gggagggata atattgcaag
    36181 agagagaaga attagtttta aatccagttc caaaagagga aagagttgga tggttagctc
    36241 cattgtttaa tatgcttggt tctaacatag ctatatctga actaatggtt ggaggaactt
    36301 taattttagg aatgactctt tctaatatga ttattacatc aattataggg aacttaatat
    36361 tagttgcaat cattatgata caaggttata taggttacaa agaagggtta aatacgtatg
    36421 tattagctaa gggggcattt ggagagatag gaggaaagta tcttatatct ctattacttg
    36481 gtataactag ttttggatgg tttggtgtac aagcaggggt tgcaggacta tcagtacaaa
    36541 agatattccc aagtgtaaac ctaacattag ttacagttat acttggatta tttatggttg
    36601 tttttgcact gtatggcttt aaagctatgg ctaaatttaa ttacttagtt ataccaccac
    36661 ttatgatatt aatggtgtgg ggagttttta aagctttttc tacttatgga gttgaagcta
    36721 tttataatta tactcctcaa acaactatga gtatggttga aggtcttaat attgtagtag
    36781 gtcttgttat agttggtgca attatatcac ctgaccagtt aagatatacg agacgagtaa
    36841 aagatatttg gattatcagt tttttaggtc tagggattat ttcattattc caacaagttg
    36901 cagctggtgt aatgtctatg ggagcaccta cttgggatat aacagaagta ttggctaatt
    36961 taggttttgg atgggtagcg tttgttattt taatacttgc atcttggtca acaaacgtat
    37021 caaatgctta ttctggtgga ttagcattaa aaactatttt tccaaatgta aaaagaaatg
    37081 ttttgacttt agttgcaggt ctaataggta caataatagc agctactggt ataatattta
    37141 aatttcagtc atttttatct ttcttgggaa tcgcagttcc tgcaatagca ggaattatgt
    37201 ggtgtgagta ttattttata caaggaagaa cttataagca tagagaagga ataaattgga
    37261 ttgcagtaat aagctggtta ataggttttg cagcgtcgta ttatagttca aaaataaatt
    37321 tcttaatacc tccgataaat ggaattgtag tgagtatggt tatttattat atattaatga
    37381 aatgttttgg aatcaaagat aaataaaggg ggcaattaca tgggtcgtaa ggtgaaaata
    37441 ggtataattc aacaacacag tgtacttgga gatgttaaaa aaaatataga aaaagcagta
    37501 gagatgatag atgacttagg aaaacatggg gcagatataa tttgtttacc agaactattt
    37561 gctacaggat ataatttaga gtctttaggt ggagttaaaa cattagaatt aataagagaa
    37621 cataataagt acatagagga atcaatgtca gaagctgcta aaagaaataa tgtatacctg
    37681 atatctccat atggaacctt agaaaaaggg tctacacatg tttataattc agcagttata
    37741 tttgatagaa aaggtaagat tatgggagaa tactgtaaaa atcatctgtg gtcattagaa
    37801 gcagtatact ttaaaggagg ggaaaaagta gaggtatatg atgctgattt tggtagattt
    37861 ggtgtaatga tatgttatga tgcaggtttt ccagaagtat ccagagaatt gacattaaaa
    37921 ggttctgaaa taatatttat accatctgca tggagaatac aagatgaaga tatgtgggat
    37981 ttaaatgtat ctcaaagagc tttagagaac actgtatata cagtaggtgt aaatttagta
    38041 agtaatgact ctaatttaat actatttgga aagagtaaaa tatgcaatcc tagaggtact
    38101 gtaataactc aattagatac atacagggaa aaatatgtat tatcagagat tgatttagat
    38161 gaaataaaaa agtataggga agatataccc tatttgaaag acagaaaaag tagctataac
    38221 atataattct atactataat acaagttcaa tataaaatga taaaaagagg atgtatcaat
    38281 attaagatta aatttattat attttgatat atcctcttta atattatcaa ctttgattta
    38341 aatattttta aaatagttga taagaaagtt tttgaacaac aacacagctt tagattcata
    38401 gttttcgcta aaccatgaaa gatttaaata tcttttaaat tcaatatctt tgatatgtaa
    38461 caacttaatc tcagggtctt gagataatcc ccatgatttt ccacatataa atccaactcc
    38521 ttgaagtgat tttataagag cataaattgt atatggtgaa tcagactcaa atgctatttt
    38581 gggtttgaaa ttagctgatt cgcacaggat atcaattacc tctctataat tctcaccctt
    38641 cgttataact ataaagtttt catctgaaac ttcgcttaga tatacttcat cctttaatga
    38701 taaaggatgg tttattgaaa ctcctaatag tatttcttcg catgttaaag ttatgctatt
    38761 ttctgagttt agctttgtaa atgaagaaga tatgtacaaa tcaaaatcac tttttttata
    38821 agatgatggc aaagtatgtg acacattaaa agtaatattg ggatatagtt ttctgaaatt
    38881 actcaaaagt gatggtaaca cattagccgc tgcaggagat aatatcttta cttctcctga
    38941 attttctaaa gaagtgtctt gtaactcctt ttttgaactt tctactaaat ctaaaatgct
    39001 atctactctt tttagaaaca atcttccata ctcatttaaa acaatatatc ttccttttct
    39061 gtcaaataac tgaactccaa gttctttttc taaggaagat atagttttgc ttaaagctgg
    39121 ctgtgctata tttaacttgt gtgatgcttt tgttatgtgc tccattctag caacagtttg
    39181 aaaatactta agatgcaata aatccatagt ataaaataca cctcttttaa tatgacttga
    39241 gttatatcaa ttttataatc aactccacat tatacattat aatataaagt ttatataatc
    39301 aactacaata tattaaaaag ttatttaaat tgttatttat attttgtaca taatctaatt
    39361 aaaaaaagta gctttaaatg attaactaag gaaatgttgt tacaaacttt agttatataa
    39421 aaaattcatt tgatgagtaa agtattaatg tcaagtaaga ataaaagctt attagataga
    39481 aaaataatat tttataataa tgatgttact taaattatta tgttatacta ttttaaatag
    39541 gaaacattta gatactataa ttttaggggg agtcaagatg aaattaacta aatcaatatc
    39601 atcaatgcta tgcttagctc tagttttaag cttatcacca gtagcatatg caaatgaaat
    39661 aagtagaaca acagtggaga atactttagt aggtcaggac agataccaaa ctgctgttga
    39721 agtaagcaaa aaaggatgga gtagtgcgaa tgaggctgta gttgtaaata gtgaatctat
    39781 tgtagatgca ttagctgtaa caccatttgc taaattaaaa aatgctccta tattattgac
    39841 agaaaaaaat aatctaaatt cacaaactga gaaagaatta aaaagattag gagttaaaaa
    39901 agtttatata attggtctat ctagttctgt atcaaatgat gtgcaaaaac agttagaatc
    39961 taataattta actactgata gagttggtgg tagtgataga taccaaacag ctttgagtat
    40021 agctaaaaaa atagaaggat taaaagatat atcagaaata gctgtagtaa atgggtacac
    40081 aggtcttgca gatgcagtta gtatagcttc tgtagctgct actaatggaa tggttatact
    40141 tccagtatct gatgcatctg gtatatctag ctttaaagat tttatagaat ctaagaatat
    40201 aaataaatca tacataatag gctctactaa tgctgtatca gataaaataa aacaaagttt
    40261 acctaattca gaaagaatag gtggagcaga tagaaatgaa actaatggta aagtaataga
    40321 aaagttttat acatctaata aattaaacaa tgtatttgtg gctaaggatg gaatgaaaaa
    40381 tcaaaatcaa cttatagacg ctctagcagt aggagtactg gcatcaaaag aaaattctcc
    40441 tgtactaatc gtaggagaac aattaagtgc aacacaaaag agtgtatttt tgaataaaaa
    40501 tgctacctct ataactcaag ttggtagtgg aggaaatgaa aatgcattta aagaattaaa
    40561 agatttacag gcaaatagta acaataagag agtaatgtat gtaactaata cagataaggt
    40621 aaatataaga aatgatgcta caatagaagc ttctgttata ggatatctaa ataatggtga
    40681 tgaagtagaa gttttagatg tgttaaaaac tggatgggta aaaataaaat acaatgaagg
    40741 tattggatat gttagtgggt cttatttgac aaataataag cctgataata gtaatgaaaa
    40801 tataaaaata aagtatgtaa aagaaaaaga tggtctaaat gttaggaaag gaccaagtac
    40861 agaagatgaa aaaataggtc acctttcata tggaagcaaa gtagaaacaa tagaaatatt
    40921 tgctactgga tgggtaaaaa taaagtataa tggtggatat ggttatgtaa gtaatgatta
    40981 cttatctgat acaccagtta tttaattata agtaacaata aaaaactgct ttaatttgta
    41041 aagcagtttt tttataaaaa tttaagtcta ataactattt ctattttgat accttaatcc
    41101 tgggatttat tattatggat attatcaaca tacaaacact ccaaatccag tgtctaattc
    41161 caaacttaga tattaataaa ttcagtcctg ctatggtaaa taagcagtat ttaattacaa
    41221 ttaaaagtgt atttatagaa atccccttca tagaaagtat cctaaatcca ataatagaca
    41281 ttctaagtcc tataaatgcc aataatatac ctgcaatatc ctgaattaag taatagtatt
    41341 caaatttcat attcaatcaa ctcttctctg agcagtatca aatatttcta actcttcaat
    41401 ttcatcatct gtgtatgtaa gcatagtaaa accagttaca ccataaataa atgaaattat
    41461 aggtgtaatc caacttaaga aacaatatgg aataaattct agtgggctta caccaagagt
    41521 ctgagcacag aaaacagcat ttgaattcca tggtattaat ggaccaccaa gtgtagctgt
    41581 atcttctata attctagata gattttgtgg ttttaattta aactctttgt atattggaga
    41641 cattagagtt ccgacaaata cagaagtaaa catcattgat gaactaaatg catttgcaaa
    41701 gtagcttact ataaaagtag acccaaccaa tttagttctt gattttccta ttttagttat
    41761 aagaggttga agcagtactt ctaagaatcc agttttttgg agaataccgg caataacgaa
    41821 aactacaaat actagtaaaa cggtttcagc catactcatt attccaccac gatttaatag
    41881 tttgtcggca tagacaaatc cagtatctat agtaaatcct gatagcatgt aatttaaaat
    41941 atcacctatt ttttctcctt cttgaaatac tgctataata agtcccatga tagctgaact
    42001 tagtatagat ataatgggtg gcttttgtag caataaaagt aataataaaa atattattgg
    42061 aatcattgct actaaaccaa tatgaaagtt tgaatttaat acatccttga tttgatttat
    42121 ttgaacatag tctatagtat tatttgaata cttaaatcca attactgtat acagaactat
    42181 acatattacg tatgcaggtc ctgtggtata aaacatatgc ttcatatgtg taattacatc
    42241 tgtcttacaa actgctgcag ctaagtttgt agaatctgat agaggtgaca tcttatctcc
    42301 aaagaaagca ccagaaatga ctgcaccagc tgttaaacca agaggaatac ccatactagt
    42361 accaatactc atcattgcta taccagaagt tccaagagtc ccccaagatg taccagtagc
    42421 aacagaagtt aatgaacata cgattaatgt tgtaagcaga aaatatttag gggttattat
    42481 tgttagtcca ctatatacta ctgttggtat tgtaccagca gctatccaag ctgctattag
    42541 tacaccaaca gaaagtataa ttaagtttga ttgaaaggca tctttaccaa cttcaaatcc
    42601 aaaagcttct atttcatcat tagtataacc aagtttcgtg gctgcaggaa ctactataag
    42661 ccatgaaagt aaaaacattg tagttataga agcattaaat acaactatac caactgatgt
    42721 tagagctatt attgcaagca ttactaacaa ggaatatcta aatgaaggta tttttctttc
    42781 tgtattcatt ttcatagtgc aaattctcct taaatatttt tatttaattg cattttttat
    42841 tcttataaga gcttcttcaa gcatacttct tggacaagct aagtttattc tttgataccc
    42901 acttcctcca atgccaaagc tgtttccttg atttagagca actttacctt tttgtacaag
    42961 tacactttct agttcctcat cacttaatcc aagtgcacta aagtctaccc ataataaata
    43021 agtaccttct ggttttctaa ctttaagttt tggcatattt tcatttatat attttatagc
    43081 aaaatctata ttagattcta aatattctaa aaatgattct agccaagatt caccattatt
    43141 atatgaagct tcagttgcaa ctaagctaaa gcaattattt ctctttatat caattctggt
    43201 aaaagcatca tctaacaatt tatagtcttt ttcatcaggt agtattacat atgatgattg
    43261 aagaccagct atattaaaag ttttagttgg agccatacaa gtaattgtat ttttttcaaa
    43321 ttctttagaa atagatgcca taggaatatg cttatgtttt tttaatataa tgtcactatg
    43381 tatttcatca gatatgattt ttacattatg cttaagacaa atatctccta gtttttttaa
    43441 ttcatctttt gtccatactc taccaactgg attatgagga ttacaaagta tgaataattt
    43501 tacatcttta atcttgtttt caatgtcttc ataatccatt atatagtttc cattttctag
    43561 tttctgtaat gggcttataa ttagttctct attgttattt tttacaacac tattaaaagg
    43621 gctgtaaact ggttcttgta tcattatttt atcatttgct tttgtgagtt catttattaa
    43681 aagacttata gctgggataa cacctggact ataaattaac cactcacttt ttattttcca
    43741 gttatgtctc ctatctagcc agtttactat agattcattg taagaatctg gtcttgttgt
    43801 gtagccataa atctcttgtt ctagtctatt ttttaaggaa tcaattatac aaggtgcagc
    43861 cttaaaatcc atgtcagcca cccacatagg aagtaaatca ttagttccat actttttttc
    43921 catttctgac catttagatg aaaaattatt gcttctatca acaatctcat taaaattata
    43981 attcattgta aatacctcca gtaattttaa ttttatgtta ataatattaa gcaaacaacg
    44041 tgccaatatt gataataaaa aatatttatt cacaagttaa tatttaatat taagtaattt
    44101 cagagcatag ataagataaa aatattaatt atacttaaaa ctttgtggaa aaggttattt
    44161 ctaataaatt tttaaatata tgaaaatgta attaaatagg ttaaataggt ttaactgttt
    44221 aacttgttag acctatttat attttttaga aattctactc cttttgatgt tataattgaa
    44281 cctccacgac caacaagtat gtctacaagc ccaaagtctt gtagttctaa aagcatattt
    44341 ctaatctgtt gttctgtcaa aaatctattt tcctctaaag ctattttaca taagcttttt
    44401 ctacctattc tttcttttaa atcataagcc ttttttaaat tatccaatat aaatatgtat
    44461 tcatctagtg accttttaaa attatagtcg tatttcatga tgtttttgtc tttgccaatg
    44521 ttgaattgat acttttttat attatcactt actttattac aaacggttct actataattt
    44581 gaatctatag tgtccaatat atattcaggt aaatcacata tttctataat atcttttccc
    44641 aagtaacaga agtattctcc taagtttctt aattctctta catttccttc ccatctatac
    44701 attttaaaga tttcttttac ttcctcactt agaataaaat tacatggaat atcatatttt
    44761 aatgaaccaa aaatttcaaa tatatcagca gctctttccc taagtggatg tattttaagg
    44821 ggaagaacat tcaacctaaa atataaatct cttctaaaca tatttttaga tacaagttct
    44881 tttaaatttc tattagtagc tgcaattatt cttacatcaa tatcaatgac attattagaa
    44941 ccaatacgtc gtacttgttt ttcttgtatg actctaagta atttagattg agaatttaaa
    45001 tccatttctc caatttcgtc taaaaatata gttccattgt tggctaattc aaataaacca
    45061 attttcccac cttttttagc accagtaaaa gccccttcat catagccaaa taattcactt
    45121 tgcagtagat tttcttgaaa agtactacaa tttactgcga caaagggacc atcttttctc
    45181 ctagaagcac tatgaatgga ttgagcaaat aattctttac cagtaccact ttcaccaatt
    45241 ataaggatag atgaatttga ttgagccatt ttattagcaa ttttttttgt attaatagtt
    45301 tgtatactag aacctaatat atcatcaaat gtgtatttac tgatattacc agagtttact
    45361 agttgtgctc ttaatttagc ttgctttttt tctaattgag aaaactttgt catctttagt
    45421 ataaatccat caaatacatt taattgtata tgtttaatct ctaaatttat atcaatatga
    45481 tttattttaa tcaatttctc aaaaaatgga gttttattgg tcaatatgtt ttgaaaattg
    45541 atgtctttta tacaatcacc aacaaatgag tcaatcattt catttgcatt tatagacaaa
    45601 atttttctag ctatatgatt atagaattga attattccat cattatttgt gcatataatt
    45661 ccatcatcaa ttatagatag taacaaatca aattgtcttt caaacttatt tgcatctaac
    45721 aataactcac ctgtactata acttgtagga attatttttt ctacgtattt ttttattagg
    45781 tcatctttta ttagatgttt taatttggtt tttgtagcaa tttcaacaat acaacttaaa
    45841 tctattattc tgtattttaa atctacaact tcacaatttt taaacttagg caggattttt
    45901 tcgccaggag ttaggattac agcatctgtg ggagtaaact caatctctgg atagcagggc
    45961 aggatattta tattgtctat tcctaatcta tgtattaaag aaattgtttc tattgccata
    46021 tctttactta agttatatac ataaataatt ttatcttttt ctaatttgga tatcatatca
    46081 atactgttct tttcaaatgt caacttggga acaatgattt gagcatcata gtgagataat
    46141 tttactattt catcgtattt taaataagca gataggagta taagtttttc tttaaaaaac
    46201 tttaaatttc cctcttcaaa tgagtataaa tttatcttta gattatcacc taagaattgc
    46261 cttatttgat tttcataaat ttctccagcg tcttttttta aacttacaat agctaattcc
    46321 atttgtttca ttttaacctc tcatacaaat ttgacttatt ttagattaca taataattaa
    46381 attagattaa ataatattat ttaattatta ttataaattt attatagact acacattgaa
    46441 gtaaaagaag tagctaaaat tattcctttt atttttgttt tttgtatcta tttggtataa
    46501 tagtattaga gcgtataata atttaggcaa aattttttaa ggaagactag aggagaatat
    46561 aaaatgaaaa aatgtcttta ctgtaatagg gatataaagt caccaaataa taaattagct
    46621 ataaaatatg atgacaatat gaatatatat ccatgtcgtg cagaatgtaa ggaaaaaatt
    46681 gaagaatata tagcaaaaaa acctacatat aagtttataa atatattaga ggttctttta
    46741 ggtgtgggcg gaatattctg ctttttgagt aaatggacta ttgcagccca agttgtactt
    46801 ggaattgatg cactggttat atttttattc ccattggcag gatttaagat gaatggaaag
    46861 ttaagtatgg aacaaactaa gaatcaaagt aggtctattg caatatcaat tttggcattt
    46921 atagtaataa taaccgtatt atattttaaa caagttggta agtagagcat aattgtataa
    46981 gacatcatta gagtatgagg tgagtttatg gaagaaagaa aattagcacc aaacaatgag
    47041 agggaagctc tcataaaaag attaaaaaga atagaaggtc aagttaaggg gatacaaaag
    47101 atggtggaac aagaacgtta ttgtgttgat atattggttc aaatatctgc tataaggtct
    47161 gctataaata gagtaggcac aattatctta gagaatcata taaaaggatg tgtagcagaa
    47221 agcattaaac atgatgatgc tgataaaact gaagagatga taaaagagct tatggatact
    47281 ataaataaat ttacaaaata aggaggcggt tagttatgaa tcaacaagga tttattatgg
    47341 aaattgttga tgatagaact gcaaagttaa aaatgcaaag acattcagct tgtgctgctt
    47401 gtggaaaatg tgctactaca aattcagcag agtcaaaaga aatattagta gaagtagaca
    47461 acacaattgg tgcaaaagtt ggtgaccatg tagaagtgag tatggataat atgaatgtat
    47521 taaaagcagc tgtaatggct tatataatac ctcttatagc acttcttgta ggaacaatag
    47581 ggacttatta tatattgggg gcaattggaa tgacaactgg agttgaagcc ataagtggat
    47641 tagttggaat ttgtcttaca ataatctgtt atttatactt aaagaagaat gacaaaaaat
    47701 ttagagacag tagagaattt ataccagtaa taacaagaat attaattgac ctttaagata
    47761 attataatta aaaaatagca atgtgctttt taaataaata ctcaatacgt atttgtagag
    47821 tttaagtaca ttgctatttt tatattttta ttttgatttt ctgtaaggaa taaagttttt
    47881 tctgattttc aaaagattca atgttcttac aaaagaagtt acaactaata caccaagtgc
    47941 tattgcagca cttagaaata gcgcatctgt accttttgac atagccaaag aataattttt
    48001 ctgaatcaaa gacaacattg tattatatag cccaattcct ggtattagag gaagaatacc
    48061 tggaattacg aacacaatag ctggttgctt tagttttctt gctaaagtct cactacacgc
    48121 tgagaccaaa gcagcagcaa taaaacctgc aaaaactgca tttgtagtaa aattaaataa
    48181 ataaacatat acaatccaac caattccgcc agttactcca gctggaagaa gtagatatag
    48241 tggagcatta aagaaaacag caaatccagc agttgcaaca cctgaaaata aaaaatgcaa
    48301 aatcatagac atatcagtca ttagaaagga cctcctattc tataccatgt atcaaggaca
    48361 aaaccaactc cagaagcaat tgcaataata atcatagcag catcaaaagc acgagaaatt
    48421 cctgatatta aattccctga tattaaatct ctaatagctt ttataaaagc aactcctggg
    48481 agtagtggca ttatagcgcc gactataagc attttagggt catctaaaat gcctatttca
    48541 actagtagaa ctcctgaaag tgcaattaaa aaagaagata ctaaacagga aaatgcagat
    48601 attgcactta tcttcatcgt tttatcataa gtaattgcag caaagattgc tattataaac
    48661 gtaagtataa aatttaatac ataattccct ccaagcaaac aagcaaaaca agcagatgca
    48721 attcctgtac aagagtaaaa taaccataaa ggataaggtt ttacatcttg gatttcataa
    48781 agacgtgcaa tggcattatc aatatcatac tctttgtcac taacaaattc tcgagaaaaa
    48841 ctgtttaata aagaaatctt gtttaagttt atacctcttg attgaatcgt tttcataaac
    48901 gaaaagccat caaatttctc atctgaaata attattactg taggagttgt aaaaatattt
    48961 acatgataaa accctcttga cctgcatatt ctaaggacac tgtcttcaac cctagatgtt
    49021 tcagctccat tttttatcat cagttcccct acaaatagag ctagttttag aatatttttc
    49081 ttatattcaa gttcctcatt ttgattcata aatacacctc caaattaaaa aacgtaatat
    49141 tgaaattata tcaaattttt aagtaatatt ccttaatatc tatataaata tattatcttt
    49201 tttttgtttc aaaatagtca catttaaatt atatccaatt aaaagaatta gacaatatta
    49261 tttattatat tttaacttaa aaataaagaa agtaactatg ttaaatatgg aaaaatggca
    49321 aaacacttga ctattaattg gtaaaggact ataataataa attatcatat tgataaaaac
    49381 gaaaattatg aaatgtctgt aaaaataaaa tttaaataat aactaggagg agtaatatgt
    49441 ttgagaactt gaaaaaagcg gatcctgaga tttatgaaag tatgaaaaga gagttaaaaa
    49501 gacaacaaag aaatattgaa ttaatagcat ctgaaaacat agtatcagtt ccagtaatgg
    49561 aaactatggg aagtcatctt acaaataagt atgcagaagg ttactcaggc aaaagatatt
    49621 atggtggatg tgaatacata gatgaagttg aaactcttgc aatagataga atcaaaaaaa
    49681 tatttggagc agaacatgct aatgttcaac ctcactctgg agcaaatgca aatattggtg
    49741 tatattttgc tatgttaaaa ccaggtgatg ttgttatggg aatgaattta tctcaaggtg
    49801 gacatttaac tcatggtgct ccagttaata tttctggtca atattataaa ttttatgaat
    49861 atggtataga taaagacagt ggacttatag attttgatga agttagaaag atagcacatg
    49921 aagtaaaacc taaaatgata gttgcaggag caagtgcata tcctagagaa atagatttta
    49981 aaaagtttag agagatagct gatgaggttg gagcattgct tatggtagat atggctcata
    50041 tagcaggtct tgtggctgct ggtattcacc aaaatccatg tgaagtggct gattttgtta
    50101 caacaacaac tcacaaaact ttaagaggac ctcgtggggg tgttattctt tgtaaagaaa
    50161 aatatgctaa agacatagac aaagcaatat tccctggtat tcaaggtgga cctcttgaac
    50221 atataattgc ttctaaggca gtttgcttta aagaagcttt aagtgatgag tttaaagaat
    50281 atcaggtaca agttgctaaa aatgcaaaag ccttagctga agaacttatt aaaagagatt
    50341 ttaaattgat ttctggaggt acagataatc atttaatact attagatttg attaataaaa
    50401 atataactgg taaagcagca gaaaagagat tggatgatgc ttatataaca gctaataaaa
    50461 atacaattcc atttgatcca aatggtgctc ttgttacaag tggaataaga cttggtactc
    50521 cagctgtaac tactagaggt atgaaagaag aagatatggc aataatcgct gaggctatag
    50581 acctatgttt aacttatgat gaagaatcta aggctagaac attggttgtt ggtttaactg
    50641 aaaaatatcc tttatatgaa gaatataata ttatggatta attataaaga acaactaaat
    50701 aaaatacatt taaataatta caatgattgt gtatgtattt gaatatattt agatataaaa
    50761 aaggtgtctc aaaatgaact ttttagttta tgaggcactt ttttgtatgg aatcgaacat
    50821 atttgtgtta tttaaataat aaaaaatatg gttatctcta tttttagatg gtctctttgt
    50881 attttttaat taaaacttta agatttctta agaattatac taggtttttc taaagattta
    50941 aagtctatac ttataagtat agtaatcata tgaaaagaaa agctttaacg aggagggaat
    51001 cttatgaagg tattaattct tacaggaaaa tttggtatgg gtcattactc agcatcaaat
    51061 tctttaagtg aagatataaa agcaaaattt gataattcag aaataacaat taaagatata
    51121 tttgaataca ttatgcctaa ctattcagat aaaatgtaca agactttttc tattcttgta
    51181 aatcggggaa gtagtcttta taatttgttt tataaatgtg ctgaaaatgg aaagaaagat
    51241 ataaaattta ctttttcaga ttatttttta aataaattag atacattact tcatgaagta
    51301 caaccaacag tagttatttc aacttttcca ttttgttctc aattagtatc aagatataag
    51361 gaaaaatata actcaaatct tcctttaata acatgcataa ctgatataag tagtcactca
    51421 gaatggatta gtaaaaatac agactgttat ttagtagcta gtaaatctac taaggaagaa
    51481 cttgttttta aaggaataga tgaatctaag attaaagtta atggtattcc agtaaaaaaa
    51541 gaatttaaaa gaatagaaca tgtaaatcat tcaactaaaa aaaatattct tataatgggt
    51601 ggaggattag gattactgcc taaatcagaa caattttaca aagaattaaa tagtttagaa
    51661 ggagtaaaaa ctactgtaat aactggtaat aataaaaaaa tgtactataa actatatggt
    51721 agatatgaaa atatagaggt agtaggttac accaatgaag tatataaata tatgaaagat
    51781 tctgacctta ttatttctaa accaggtgga ataacactat ttgaaacaat ttattcagaa
    51841 cttccaatat tggcatttaa tccattttta caacaagaga tagataatgc tagttttata
    51901 ttaaataatg aaattgggag aatacttggt aaaaataaaa aatactatgt agatgagata
    51961 aaagatttaa tttatgatga tgctactctt aaagaaatga gcagtaacat gaaagaatta
    52021 aaaaaacaat ttgacaataa taccttagag aatattttat tttcacttga tgaacaagga
    52081 gcgtgtagag aatgtatgta gtaggtttaa ttatcgttgt tgcattgatt tttttagtcc
    52141 attcaattat acctacatac tataataaac tattaaataa agaggtatta aaaaatatgg
    52201 ctggagaaaa tgaaattgca cttacatttg atgatggtcc agataagaga tatacagaaa
    52261 aattactaga tgtgttaaaa gaaaatgata tacaagctat gttttttgta gtagcaaaga
    52321 atgctgaaaa agagcctgaa attataaaaa gaatgttgag agaaaatcat atagttggtt
    52381 tacattcatt ggaacacaga aatgcatggc tttatagtta tagttatgtt aaaaaagatt
    52441 ttattgaaag tacaaatata atgaaaaatt taggtgtaga tgtaaactac tatcgtccac
    52501 catggggtca tactaatata ttttcaaatt catttgttaa aaaatataat ctaaaaatga
    52561 ctttgtggga tgtaatggca gaagattggg agaaagatag tacagtagac attattataa
    52621 acaagttaat gagtagaaca aaagaaaatt ctataatttg tttacatgat gcaggtgaaa
    52681 attcaggtgg tgcagtaggt gcacctgagc gtactattga agctttaaag atagctattc
    52741 caaaacttaa agccagtggt ttaaagttcg taacaccaga aaggatgtag ttatgataag
    52801 taaaactgaa aagaaaaata aatgcctagg tagtgtagct tttttagttt tactaatggg
    52861 cataacagga tattttgttt ttagagggca gtcagttgaa tcattgataa aatcattaaa
    52921 aggtgcaagc cctatgttta tactaattgg atttgcaatg atgtttatat atgttgcctg
    52981 tgaaggtata aatatatact taggtatgaa agctttaaac caaaaaacta ctcttttaaa
    53041 atgtatggga tatgctttta ttggatttta ttttagttct attacgcctt cagcatcagg
    53101 tggtcaacca gcacaagttt attatatgaa aaaagacgat ataaatatat catattcttc
    53161 acttatacta ttagtcattg ttgttattca ccaagtagtt atactggcat atagtggaat
    53221 aatgttcatt atggaacgtg agtttatatt aaataatgta agtggtatga acattttact
    53281 aatatatggt gtaataacaa atgttgctct tgtcattgga gtaattgcaa ttatattttc
    53341 aaaaaaactt gtaaacaatt ttataatatc aataacaaat ttattaggta agttaagaat
    53401 aataaaagat gttgaaagtt caagaaaagt tataatatct caaattgaag agtatgttaa
    53461 aggtgctcaa tatataaagc agaatccaaa acttgtagtc caaattttag tcataactat
    53521 tgtacaaata acagctatgt ttttagttcc tttctttgta tacaaagctt ttcatctatc
    53581 aacatatact gtatttgaga tattagcgat acaatccttg cttaatattg ctgtttcttc
    53641 attaccattg ccaggggctg ttggagcttc tgaaaatagt tttatgacat tatttaagat
    53701 atttttccct ggtcacttat tagttccggc aatgttactt agtaggggaa taagttttta
    53761 tgcatttgta gctataagtg gattgatatg tatagtagta catgtaaaat cttctgaaaa
    53821 agtaaaagca gtgaaaaaag ttgcttatgt aagataatat tatatagatt atttttatta
    53881 atatgtcaat ttgtgtgtac attttaatta agttttaaac atgtttacag gagtataaac
    53941 tattaaaacg tgtgacattg ctaagctttt gctaataaag tataatattt tatatagttt
    54001 gaaatattta agaaatatag caaaaaaagg agcttggtga tgaataaaga gattccaaaa
    54061 aaaattttag tagctgatga taatcctgag attagggaaa tcgtagaaat acttttaact
    54121 ggtgaaggtt atgaagttat tatggcaacg aatggagaag aagctgtaaa cttagtagat
    54181 agtacgattg atttgattat tttggatgtt gtaatgcctg taaaaacagg atttgttgca
    54241 tgtaatgaaa ttagagaaaa aacgacagca ccaatattat ttttaactgc aaaaactcaa
    54301 gactctgata aagttattgg attttcagca ggaggagatg actatttatc aaagcctttt
    54361 tcatattctg aactaatttc aagggttaag tcgctactta gacgttatta tatataccag
    54421 ggaaaggaaa aggaaagaga gccaaatata ttaaaaacaa aagagttatg tgtcaattta
    54481 gatactcaag atgttacact aaatggagaa cctgtgtttt tgacaactat agaatatagt
    54541 atattaattc ttatgttgaa aaatagaaaa aaagtttttt cgtctgaaaa tttatatgaa
    54601 actatttggg atgagcagta tttttatacg gcaaataata caataatggt tcatattaga
    54661 aatttaagaa aaaagttaga aaaagaccaa aaaaatccac aatatataaa aaccgcatgg
    54721 ggaaaggggt attatattga ttaacaaaat taagccatct aagttgggag ttatactatt
    54781 gatatatgta gtaatctcag ctgcagtggc tttcatttta aatataccat tttactctgc
    54841 tgttgaatct atagtaaaag atgtatcaga agggaaagta tattttaaaa gagaagtaaa
    54901 tcaacttatg gataattttc aaacttatgt gaataacaat ggtataagag cagatgatgg
    54961 agatgatata gcaaaatgga atagtgataa ttggtttgtt tctatgaaga tatataaagg
    55021 aaataaggtt ttttatgata cattatacta tcctaatgaa gtacctgata agagtgagga
    55081 aaatgagttt tatagcagtc ccatggctag aaactatgag atacaatttt ctgatattaa
    55141 agctaatata gttgtagtag ctttatttag atttagattt caaaatttta tagaagcaat
    55201 ttctattaca tttatggcac ttacatttat tataacattt ttactgttgt ttagtagaaa
    55261 gataaagtac ctaaggaaaa tagaaatggg tataaagata gtagagagtg gcagtttaaa
    55321 gtatagaatc ccagtaaaag gtaatgatga attatcatca cttgcatcta gtattaatga
    55381 gatgagtcat acattggaga atcaacttat aaaagaaagg gagatgaaga ataaaaataa
    55441 agatatagta acttcgatat cacatgatgt tagaactcca ttaacatcag taatttgtta
    55501 tttagatttg atcaaagacc ataaatacaa tagtcctgag caattggaac aatacataaa
    55561 aaatgtaagg tctaaagcat atcaaataaa agatttaaca gatgaccttt ttacgcattt
    55621 tgttaattct ggagaggaag tttcaaaagg gtatgaaaaa ataaatgcta atgaatttat
    55681 ttttcaatta cttttagata gttcatatac attggaggag aaaggatttc atataacaat
    55741 agaaaatgaa ctttataacc aatatcatat ttatgtagat gttacacaat ttagaaggat
    55801 atttgataat ttatgttcta atataataaa atatgctagg aaagataagc ctatagtatt
    55861 tttaattaaa gtagaggatt ctaaattact aattatacaa aaaaatagag taagtaattt
    55921 ttctaagaat gtagaaagtt ttggaattgg tataaagaat tgtgagaaaa tagttgcata
    55981 tcataatgga agcataaatg taaattcaga tgataaagaa tttgctattg aaatatctat
    56041 tccagcaaaa gaatcataaa aatttaaatt atatattgtg taattgctat tatatattgt
    56101 gtaattgctt atgtaaaatt ctatgaagca ggaagcatgt gactttagtt atgggatgtt
    56161 caatattgtg tacctctagg caagtaacaa gtttacttac aagaccatat aatattatta
    56221 tcttaaaaaa aggggacata ataatatggt tttgacagga gcacattata tttacattct
    56281 atttatggta attatattaa ttactatgat tatgaaaaag gatacaatag taccatgtat
    56341 attaggtgtt ttttttatgg gattgttctt tgaaaaaaac atctttggtg ctataacagc
    56401 agtgtttaac tcttttatta tatctttaaa tgagttgggt ccaattatct tgattatagc
    56461 tattatggtt gcattatcta aagccctaga agccaataat gctatacagt atatggtgag
    56521 accattttcg agagttataa aaaattctaa tacagcattt tttgtaactg gatttgttat
    56581 gttagttctt tcttggtttt tctggccaac tccagctgtt gccttagttg gagctgtatt
    56641 tttacctgtt gctatgagag ctgggctacc agcaattggt gttgcagtag cattaaattt
    56701 atttggtcat ggtcttgcct tgtctacaga ctttgttatt caaggagctc caagtataac
    56761 agctggtgca gcaggtgttg cagtatcata tgttataaat gatggtatga ttttgttttg
    56821 ggtgatggga atcgtaacca tatctatggc attttataca ttaaaaagag atattaacaa
    56881 aggaatgttt agagaagaac taaaaggttt tgaaagtgaa gaagtagaag agttcaatgg
    56941 aaaatctaaa atagcaacta ttttagtagc tctgggattt cttgctgata taattgttat
    57001 gtatatattt gacctaaaag gaggagatgc atcagctctt ttgggtggaa cagcagtatt
    57061 tttaataata attataaatg ttataaattt tggcaaagat agtcttgaaa atgtatgtga
    57121 gaatataatt gatggttttg tgtttgggat aaaaatattt ggagcaatta taccaatagc
    57181 agcatttttc tatatgggtg aagttgcgcc cttgacaggt gtatttggaa aagtattagc
    57241 accaggttca caaggtttat tatcagatat aggcatagct ctttctcaaa caataccact
    57301 taataaattt gccgtatcag gtatagaaac tgtagtgggg gcaataactg ggcttgatgg
    57361 ttctggattt tctgggattt cattagttgg ttcacttgcc tctgtatttg gaactgctat
    57421 aaatgcaagt gttggtgcat tagctgcatt aggacaaatc agtggtatat gggtaggtgg
    57481 aggctgtcta gttccttggg gtcttatttc agcagcggca atttgtgggg ttagtccaat
    57541 agagttggca aagcgaaact ttgtcccagt tataaccgga ttggttgtaa caaccatagt
    57601 agcaatgttt attatttaat aaatcgaata aatctttaat tgtacaaatt aaaaatagat
    57661 gtgtagctat aatttattat aattgtttta ctaattttaa gccatacatc tatttttatt
    57721 gatattttta ttagtattct ttaataaaat aatatttttc attatactat acataacatc
    57781 taaatataac atctaaaata ctgttatcta tgtttaatat cttgccaaat tttttgatgt
    57841 tttattaccc tgtcccacca acatatataa gctatcgcaa gttttttacc tatactatca
    57901 ccaaacaaaa attttaattt taatttatta ttttataatc tatattatat taactatatt
    57961 agtttgtaga ctttagatgt aattctaaat attaatactc caagagttca aattcatatc
    58021 ctagttttct tgcatttgat ataaaatcat ttaaaatttc tgtactagtt ttggaaactg
    58081 catgtagtaa caagatagaa ccatcatgta gattatccat tattttttgc gttgcttctt
    58141 catgtgatgg ttgtttatca gtatcccagt ctctgtatgc aaaactccaa aatacagtct
    58201 tgtatcctaa atttttagtc attgccaagc ttttttctga gtattttccc ataggaggtc
    58261 taaaaaattt aaccatatct ttcccagtta catctttata taacttttca acatcatata
    58321 attcgtcatt aaagtttttt agattgcttg tttttgttgg catagatgga tgggttttac
    58381 tatgatttcc aactatatgt ccctcagaaa ccattctttt tactaaatct ttattttctt
    58441 ttatatatgg agctgtaaca aaaaaaactg ctttaacctg gttttgtttt agagtgtcga
    58501 gtatctttgt agtgtatcca ttttcataac cttcatcaaa tgtaagatat agtgtttttt
    58561 gaccatcttt tgtaggtcca ttgtataggg catcatagtc agaaaattta aattcaatgt
    58621 ccgtatttac ttctggtgtt ttatgcttat tgttaggtat ataaaaccaa tcaagagtag
    58681 tgttatctaa agaagataca tctaatttat tattatcatt attagtagtg gcttttgatg
    58741 gtttatctgt tccgtctgaa actattacat tggaagtatc cttaccacca tctatttttt
    58801 ccttatcttc ttgtaactgt gtttccttat tttgattttc gttttgattg ttttgtgaat
    58861 ttgaacatcc aacaataaaa aaaatagaaa tagaaagtag tgttaaataa tgcaatactt
    58921 ttctaaacat tttgaagctc ctttctaaat taataataat tgcatatagt attattataa
    58981 ttggaaatta ctattaataa tagttatatc tttaaaaata aagtcacaat agtatgacaa
    59041 agggtgaata atcaataaat ttaaaaaaaa atgaaaaaaa tagttgacca tattatgaga
    59101 agatgttatt ataataaatg tgctcaacaa gaagtaacaa aataacaagc acaaagaagt
    59161 taattgaat
//
LOCUS       DAMJWO010000009        58690 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.010, whole genome shotgun sequence.
ACCESSION   DAMJWO010000009 DAMJWO010000000
VERSION     DAMJWO010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58690
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.010"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            114..1310
                     /locus_tag="PC366_000646"
     CDS             114..1310
                     /locus_tag="PC366_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HDF2576196.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
     gene            1403..1927
                     /locus_tag="PC366_000647"
     CDS             1403..1927
                     /locus_tag="PC366_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HDF2576197.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDTCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            1952..2128
                     /gene="rpmF"
                     /locus_tag="PC366_000648"
     CDS             1952..2128
                     /gene="rpmF"
                     /locus_tag="PC366_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDF2576198.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            2335..2892
                     /gene="fapR"
                     /locus_tag="PC366_000649"
     CDS             2335..2892
                     /gene="fapR"
                     /locus_tag="PC366_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HDF2576199.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            2903..3925
                     /gene="plsX"
                     /locus_tag="PC366_000650"
     CDS             2903..3925
                     /gene="plsX"
                     /locus_tag="PC366_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HDF2576200.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVALNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDINQFISKYNEEN
                     KNNEDE"
     gene            3951..4937
                     /locus_tag="PC366_000651"
     CDS             3951..4937
                     /locus_tag="PC366_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HDF2576201.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            5046..5975
                     /gene="fabK"
                     /locus_tag="PC366_000652"
     CDS             5046..5975
                     /gene="fabK"
                     /locus_tag="PC366_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HDF2576202.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            5991..6941
                     /gene="fabD"
                     /locus_tag="PC366_000653"
     CDS             5991..6941
                     /gene="fabD"
                     /locus_tag="PC366_000653"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDF2576203.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNAVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQIDLKYNACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQETVPAGVGAMAAILGLDRNVLENVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLKEAGVKLASELEKV
                     NITKPKVDVVANVNADYYKNEGKDLLIKQVSSSVLWEDSIEILLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            6941..7690
                     /gene="fabG"
                     /locus_tag="PC366_000654"
     CDS             6941..7690
                     /gene="fabG"
                     /locus_tag="PC366_000654"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HDF2576204.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIESMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTRVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMSSYITGQVINVDGGMVMQ"
     gene            7744..7968
                     /gene="acpP"
                     /locus_tag="PC366_000655"
     CDS             7744..7968
                     /gene="acpP"
                     /locus_tag="PC366_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDF2576205.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            7997..9235
                     /gene="fabF"
                     /locus_tag="PC366_000656"
     CDS             7997..9235
                     /gene="fabF"
                     /locus_tag="PC366_000656"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HDF2576206.1"
                     /translation="MNKRVVITGLGCVTPLGTGKEEFWSNIKSGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAIVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADIMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            9461..11179
                     /locus_tag="PC366_000657"
     CDS             9461..11179
                     /locus_tag="PC366_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2576207.1"
                     /translation="MNFRLPKKRLPKKIIFICIILISIILFIKYDQNGLKEREIINKG
                     KYMSESLVADKEYDEAKKVVKTSFESIPEKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDVKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASIFLNIGSYETGEKLIKDSFKIDIDEGEKNGMVRLYAIINLAEIYVEEGEY
                     DKAIEISSRIKDYKKFVNTDNYNDFDIMASIMKSNAYVGKNNIQKAKTFLEKADYLIK
                     SDRTVYILDKDMYYYMAMGNLEYKSENYNSAIDNYKKSLEISTKRKLTQEKIKNLNKI
                     LNIYEKQGNIESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESKLFEKTKKEIK
                     YYKILFTVILIAILGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYREKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDTVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGEEVADIIDNIRVAIANKKWNDDVTVTISAGVAHISDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            11210..13210
                     /locus_tag="PC366_000658"
     CDS             11210..13210
                     /locus_tag="PC366_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2576208.1"
                     /translation="MKQSIAIVTDKITKLSSFLEENIRLVLGNYIDINHYYLEVLKEN
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKEKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGIINTFNKEALKILGINENPQGKNIEDIISEDLNILLEDKEIIDE
                     VVFTNKKYINVNKKSIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMVKCVELAKKISKSDLSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLLKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNVRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYIRVECANNYEDGFGYTKKEFEEILRILYERRESSSGVGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            13558..13803
                     /locus_tag="PC366_000659"
     CDS             13558..13803
                     /locus_tag="PC366_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HDF2576209.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGLKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            13838..14563
                     /locus_tag="PC366_000660"
     CDS             13838..14563
                     /locus_tag="PC366_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HDF2576210.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDINPQLYGEETREETTFIYPEVDEFDLIAISI
                     ALELKKPILGVCRGLQILNVSLGGTLYQDNNLIEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGIIEAIEKEEENFVVGVQWHPE
                     MMVDYCDKMEKLFKYFINICSNL"
     gene            14585..15898
                     /locus_tag="PC366_000661"
     CDS             14585..15898
                     /locus_tag="PC366_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2576211.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKSFGVASIFVY
                     IFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVAMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTSSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARICFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKVCGENLKKIV"
     gene            16197..16643
                     /locus_tag="PC366_000662"
     CDS             16197..16643
                     /locus_tag="PC366_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2576212.1"
                     /translation="MGGETHFLSFGKDEYKISLEEQENAIESAKASDNSVKLIAFIDD
                     EIVGIATIDSNQKAKGKHVGVLGIVVKEKYWGIGLGKRLMLDLIEWCKSNGITKKITL
                     VTNEENYNAIGLYKKVGFEVESILKKECYYNGVYTDLIGMSLLLGI"
     gene            16732..18717
                     /locus_tag="PC366_000663"
     CDS             16732..18717
                     /locus_tag="PC366_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HDF2576213.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTITLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIEEKET
                     HKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGVKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            18941..19909
                     /gene="spoIIIAA"
                     /locus_tag="PC366_000664"
     CDS             18941..19909
                     /gene="spoIIIAA"
                     /locus_tag="PC366_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HDF2576214.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKVSNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMTLDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKAIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGAYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIDD
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            19899..20420
                     /locus_tag="PC366_000665"
     CDS             19899..20420
                     /locus_tag="PC366_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HDF2576215.1"
                     /translation="MQIKIIIIALLVGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGGNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            20437..20634
                     /gene="spoIIIAC"
                     /locus_tag="PC366_000666"
     CDS             20437..20634
                     /gene="spoIIIAC"
                     /locus_tag="PC366_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HDF2576216.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            20650..21036
                     /gene="spoIIIAD"
                     /locus_tag="PC366_000667"
     CDS             20650..21036
                     /gene="spoIIIAD"
                     /locus_tag="PC366_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HDF2576217.1"
                     /translation="MEIMQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVM
                     FKLNFIVDSIQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEF
                     GGKIIVMSMSFPILLSIVEMVVNIIP"
     gene            21121..22326
                     /gene="spoIIIAE"
                     /locus_tag="PC366_000668"
     CDS             21121..22326
                     /gene="spoIIIAE"
                     /locus_tag="PC366_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HDF2576218.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSEDKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLIGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTVYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            22386..23003
                     /locus_tag="PC366_000669"
     CDS             22386..23003
                     /locus_tag="PC366_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HDF2576219.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGNYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNSAKSNNSSNEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLNLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            23015..23569
                     /locus_tag="PC366_000670"
     CDS             23015..23569
                     /locus_tag="PC366_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HDF2576220.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKSDKQVGK
                     TETNKNAEKQVTKKQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            23596..24285
                     /locus_tag="PC366_000671"
     CDS             23596..24285
                     /locus_tag="PC366_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HDF2576221.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDDSDSSKTEDSSNVDKQGGKESADIDIVDSKASKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNSNK"
     gene            24395..24757
                     /locus_tag="PC366_000672"
     CDS             24395..24757
                     /locus_tag="PC366_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDF2576222.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            24842..25348
                     /gene="nusB"
                     /locus_tag="PC366_000673"
     CDS             24842..25348
                     /gene="nusB"
                     /locus_tag="PC366_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HDF2576223.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDKVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            25332..26402
                     /locus_tag="PC366_000674"
     CDS             25332..26402
                     /locus_tag="PC366_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HDF2576224.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVIFNEKIMLEVRDNSK
                     GLRQSEAVFQHINNLGILSDRIKSFKDKFNVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     KLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNKFISVHMSGGTTEILLTSKQDSHH
                     NVCDTNLGKIAKISIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGIKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIINDNGDNTNQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVNEVVFAGGVSASKYILRELSMKLRKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            26399..27604
                     /locus_tag="PC366_000675"
     CDS             26399..27604
                     /locus_tag="PC366_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HDF2576225.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
                     YPKVNIKLYPVMVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLE
                     DEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECM
                     IDKIENKEG"
     gene            27606..27821
                     /gene="xseB"
                     /locus_tag="PC366_000676"
     CDS             27606..27821
                     /gene="xseB"
                     /locus_tag="PC366_000676"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HDF2576226.1"
                     /translation="MNLTYEEAYKRLESILSELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            27824..28711
                     /locus_tag="PC366_000677"
     CDS             27824..28711
                     /locus_tag="PC366_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HDF2576227.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIEKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDEAKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLKGLAEYIIDREY"
     gene            28741..29178
                     /locus_tag="PC366_000678"
     CDS             28741..29178
                     /locus_tag="PC366_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HDF2576228.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGIVTALILM"
     gene            29212..31077
                     /locus_tag="PC366_000679"
     CDS             29212..31077
                     /locus_tag="PC366_000679"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HDF2576229.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KENESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYIDTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKELIDILRKAKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSAKVKSMSISVGEKLVDMANNNED
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     REMELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDDGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEGMLKALLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNIDELYDFVGLSPKSIADKIRKLVIE"
     gene            31210..32022
                     /locus_tag="PC366_000680"
     CDS             31210..32022
                     /locus_tag="PC366_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HDF2576230.1"
                     /translation="MKKRIDLLLVEQGYFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCSIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEYTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEVVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNEGYEFDGETYNNKIVEVVEASHNLDK"
     gene            32042..33721
                     /gene="recN"
                     /locus_tag="PC366_000681"
     CDS             32042..33721
                     /gene="recN"
                     /locus_tag="PC366_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HDF2576231.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNRYLKKILEENDISMEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKNVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYGKIK
                     DRLDEILNRDERVEQLKSKLMNIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGSFTLDGVDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            33936..34802
                     /locus_tag="PC366_000682"
     CDS             33936..34802
                     /locus_tag="PC366_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576232.1"
                     /translation="MNKKDTMHLIFIIVIFILLWYIVVAVSEINKNIESCSNKLDYLS
                     QELMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECTIDVDVQLSKLGKNGKVFF
                     MYKEDSDKWNETEMTKHGELSYACEIKINTGSEYDYKVVTSGDISESSDVQKLTKSDY
                     MPEQPIFNSGIRDNREYFIEIVENSNLFNHESEKSKNKAYDNIRLEKVDIIVNEGKKD
                     TIYKAQLAEGLDDGKTNNSNRNQVNYEVSFPKRDIDDIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEK"
     gene            complement(34893..35384)
                     /locus_tag="PC366_000683"
     CDS             complement(34893..35384)
                     /locus_tag="PC366_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2576233.1"
                     /translation="MADKMAQNITLQFVEEKDLENLENVKLLFTEYSNSLNIDLCFQD
                     FNNELKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKI
                     GKILLEEIIVEAKKIGYTHMRLDTLPSMKSAQGLYEKFGFYDIELYTYNPIEGARYME
                     LKL"
     gene            complement(35445..35885)
                     /locus_tag="PC366_000684"
     CDS             complement(35445..35885)
                     /locus_tag="PC366_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2576234.1"
                     /translation="MKLNVRIADINNWHDLVSLSVDKSQLDYIESNALSIAESKFITA
                     WVPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGKGCGKASLDFLVNHLKNEY
                     NCDELYLSIFEDNKMAIKLYKDFGFKFNGELDYGGEKVMVLKSN"
     gene            36046..37104
                     /locus_tag="PC366_000685"
     CDS             36046..37104
                     /locus_tag="PC366_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HDF2576235.1"
                     /translation="MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTI
                     KNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVGYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            37246..38070
                     /gene="spo0A"
                     /locus_tag="PC366_000686"
     CDS             37246..38070
                     /gene="spo0A"
                     /locus_tag="PC366_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HDF2576236.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            38483..39604
                     /locus_tag="PC366_000687"
     CDS             38483..39604
                     /locus_tag="PC366_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576237.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSHQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            39622..40497
                     /locus_tag="PC366_000688"
     CDS             39622..40497
                     /locus_tag="PC366_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HDF2576238.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFNILKEKNDKLDSDLASVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIVLKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNSLGNTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            40521..41213
                     /locus_tag="PC366_000689"
     CDS             40521..41213
                     /locus_tag="PC366_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2576239.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDIKQINEIIVVDDGSIDN
                     TAKVVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADIIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            41221..42045
                     /locus_tag="PC366_000690"
     CDS             41221..42045
                     /locus_tag="PC366_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDF2576240.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKDLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIIFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            42050..43117
                     /locus_tag="PC366_000691"
     CDS             42050..43117
                     /locus_tag="PC366_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HDF2576241.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGKIQRAYNYPKISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFAASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADAVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLDKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            43119..43655
                     /locus_tag="PC366_000692"
     CDS             43119..43655
                     /locus_tag="PC366_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2576242.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     IKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVYEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            43723..44328
                     /locus_tag="PC366_000693"
     CDS             43723..44328
                     /locus_tag="PC366_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HDF2576243.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVVGSYINKILPGSSNN
                     ILNNINPAVEYYNLNISIKDTVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILALISLSYFKEMVYEFKKKNR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTVSIGIIKFLAK"
     gene            44340..45254
                     /locus_tag="PC366_000694"
     CDS             44340..45254
                     /locus_tag="PC366_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2576244.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLV
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICTNNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKNQRVIPLCDITKLYLEKYLKEARPKMAVEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDVELQKAEAK"
     gene            45296..46468
                     /locus_tag="PC366_000695"
     CDS             45296..46468
                     /locus_tag="PC366_000695"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDF2576245.1"
                     /translation="MSRVIWIVIDSVGIGALPDAEKFGDSKDVSTLGNIFKEYPDIQI
                     PNMRNLGIGNIDGIDFFESIKEPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIEEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKEDLF"
     gene            46515..47327
                     /locus_tag="PC366_000696"
     CDS             46515..47327
                     /locus_tag="PC366_000696"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDF2576246.1"
                     /translation="MFEKIAQSSKFINSKSNIKPKIGLILGSGLGDLANDIEDPVTIK
                     YSEIPNFPVSTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEILIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRFGARFPDMSDAYSS
                     KYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQPLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            47531..48856
                     /locus_tag="PC366_000697"
     CDS             47531..48856
                     /locus_tag="PC366_000697"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HDF2576247.1"
                     /translation="MRMYDIIKKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEVDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFIDSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLISSSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFELA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAHDFEDGVEKIRESIKSGTAIQKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSIKSGYISKIKAEDVGVSAMILGAGRETKDDILDLSAGIILEKKVGDYVNEGE
                     VLAYMYYNDEQKLSLAKGRFIDSYSIVDSKIEKNKLIYGIVTKEEIKKF"
     gene            49069..50148
                     /gene="mltG"
                     /locus_tag="PC366_000698"
     CDS             49069..50148
                     /gene="mltG"
                     /locus_tag="PC366_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HDF2576248.1"
                     /translation="MNFKENRLKIAVLIIVILIILAGIFVFIQIGPYDKNNKKDVIID
                     VPSGASVGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFPYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKELNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPEKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            50320..50994
                     /locus_tag="PC366_000699"
     CDS             50320..50994
                     /locus_tag="PC366_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HDF2576249.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKVQKPKRILEVGCAIGYSSIFFASIIGKDADIITVERNEKMIEKAKENIKL
                     AGFDNNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRNYLDYICNCDYLSTSLVPIGDGVALSYKESKRG
                     DVDGIK"
     gene            50981..52228
                     /locus_tag="PC366_000700"
     CDS             50981..52228
                     /locus_tag="PC366_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDF2576250.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEISEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YRAPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEEMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            52300..53964
                     /locus_tag="PC366_000701"
     CDS             52300..53964
                     /locus_tag="PC366_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HDF2576251.1"
                     /translation="MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYAKDGLLS
                     HTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTVD
                     NKDKDRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQNDIS
                     KSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNTNE
                     ILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDE
                     EKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNMNT
                     IKTYKSSKKEELISPYVCTQVKEYMKSVSRIGTAKDLKDIEGGCGVKTGTAQSSLNKK
                     AIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK"
     gene            complement(54061..54345)
                     /locus_tag="PC366_000702"
     CDS             complement(54061..54345)
                     /locus_tag="PC366_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2576252.1"
                     /translation="MCNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTPRER
                     EIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            complement(54368..55885)
                     /locus_tag="PC366_000703"
     CDS             complement(54368..55885)
                     /locus_tag="PC366_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2576253.1"
                     /translation="MSVAIYLRKSRADEEAEKQGEFETLSRHKSTLLKLAKEQNLDVI
                     EIKEELVSGESIIHRPKMLELLKEVEENKYDAVLVMDLDRLGRGDMKDQGIILETFKE
                     SKTKIITPRKTYDLTDEFDEEYSEFEAFMARKELKLISRRMQRGRIKSVEEGNFIGTS
                     APFGYDAVTTGRKERILVPNKDADVVRTIFDLYINEDMGCSKISKYLNNLGIKTATGA
                     NWYNSAITNIIKNKVYCGYIQWQKKDYKKSKNPNKIKTVKLRPKDEWIEAKGKHEPLI
                     SEITWKKAQNILKKNGHVSYGNQIKNPLAGIVICKNCGRPLVYRPYADHDYIICYHPG
                     CNKSSRFEFIEAAILKSLEDTVKKYQLKACDLDLDKNNKDSNIEFQKRVLKGLETELK
                     ELGKQKNKLYDLLERGIYDEDTFIERSNNISSRTEEIKDSIKTVKNRLSTVKKDNSKI
                     IEDIKTVLSLYHDSDSLGKNKLLKSVIDKAIYYKSKEQKLDSFELMVHLKLHEDQ"
     gene            complement(56010..56831)
                     /locus_tag="PC366_000704"
     CDS             complement(56010..56831)
                     /locus_tag="PC366_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2576254.1"
                     /translation="MIISKKITAILVSFLIMISMVGCAPKESATEVAKKYLDSIEIKD
                     YEVAYNLLSKDSKESVSLEKFEEYQDTLFKLQTLKDYKLGEENKVEKYKYSNKEYTNL
                     VKIKETDTIKYITENKEDTANFDRYFIIEDNEYKLLWHKDFKRALSSNYVKIARSETK
                     KDEDKDYNKAAIDIKKAIEIDDKNPLAYYTQSYIYIELQRYDEALKSIDKSLEYLDKN
                     NEAYKIDASDAYNLRGVIFMSKSEFNKARESYNKALELNPDNEYAKTNLNDIKGL"
     gene            57022..58449
                     /locus_tag="PC366_000705"
     CDS             57022..58449
                     /locus_tag="PC366_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp26"
                     /protein_id="HDF2576255.1"
                     /translation="MKIKKLLTIGLSLSIFIASCPISANALDKIESIKGADKYETAGI
                     IADKQNYTTAILINADSTMADGLSASGLAGAINAPILLTKKNNIPNATLKRLEKAKKV
                     YIIGGENSINKYTETVLKGKGIEIKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAF
                     KGEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMNDKLVKDTNSTR
                     LGGTDRYDTNKKIINKFYSGVKEFYIASGTDLVYALVGSTIAKNNAIVLVGNDSNKSV
                     LKSTIKLTAIGNLSDSILQQCLNVTKNIGDSNTGREYTVEDAANAVKKLLGVKKFYYE
                     PNYSEDEDLIFLLDKNFDFSGKEYYVFAYIKQGAEGDVRYCVAKNDMSKVYTYDVNGN
                     MKVCNPDDYKNKGSITEEQAKQIALKECAKRHKVSINNLVVDMIDFRDDIYSGNVYAV
                     KINSKNSNGTFGWFFIDIETGKIYN"
BASE COUNT        23505 a         6098 c        10728 g        18359 t
ORIGIN      
        1 tacaataata tatctataac aaaataataa aagatagagt tttatttaga catttattac
       61 aaatcaaaat ttattacata ttatttataa aaaaatctaa ggaggaaata ataatgaaaa
      121 tattagtatt aaactgtggg agttcttcat taaaatatca attaatagat atgaataatg
      181 aagaagtttt atgtatagga ttggttgaaa gaataggaat agaaggttct atattaaaac
      241 atgaaaaagc aggtagagat gataaatacg ttgttgaaca accaatgaag gaccacaaag
      301 atgcaatagc attagtttta gaagctgttg ctcatccaga atttggtgca gttaaagaaa
      361 tgaaagaaat agatgcagta ggacatagag ttgtacatgc tggagaaaaa tttgcaactt
      421 cagtagtaat aactccagaa gtagaagaag ctttaaaaga atgtatagat ttagctccac
      481 ttcataatcc agcaaacata atgggaatag atgcttgtaa agctatactt ccagatgtac
      541 caatggtagg tgtatttgat actgctttcc atcaaacaat gcctaaatct tcatacttat
      601 atggtttacc tcatgagcta tatactaaat atggggtaag aagatatgga ttccacggaa
      661 cttctcataa ttatgtatct cagagagcag cagagatatt aggaaaagat ataaaagatt
      721 taaaaatagt aacttgtcac ttaggaaatg gtgcttctat agctgctgtt gatggtggaa
      781 aatgtgtaga tacatctatg ggattcactc cattagaagg attaataatg ggaactagat
      841 gtggagatat agacccagct atattaccat tcttaatgag aaaagaaggt ttagatgctg
      901 atggattgga taaattaatg aataaagaat ctggagtata tggaatgact ggaatttcta
      961 gtgacttcag agatatagaa gatgcagcta aaaatggaga cgaaagagct caggctacat
     1021 tagaagcgta tgttaaaaaa gtacaaaaat atataggcgc ttatgctgct gaaatgaatg
     1081 gattggatgt tgtagtattt actgcaggcg ttggtgaaaa tggaaaggct ataagagcag
     1141 atattgcttc taacatggag tttttaggaa tgaaattaga taaagaagct aatgatgtta
     1201 gaggaaaaga aacagtaata tctactgctg attctaaagt aaaaatgctt ttaataccaa
     1261 ctaatgaaga attaatgata gctagagata cattaagatt ggtaaaataa ttaaattaaa
     1321 cctatgccta tcaagtaaaa atacttgaca aacaaatgct agatttgtat aataaatttg
     1381 gtgatatgtt gaggtgaact taatgaaagt tagcatagaa aaaataaata gaaaagaaac
     1441 tgacaaaata gacttgaatt tttgtgaaaa aattgatact attagttatt gtgatgagat
     1501 ttacaaatta gtatcacctg taaatttaaa agggaaagtg tcaaagacta ataaaggttt
     1561 gtatctagat atagatgtca attttacaat tgttgacact tgttcaagat gtcttaaaga
     1621 agtagaaata ccactagagt attctataca aggtttttta gtaaaagaag aagattatga
     1681 tgaagatgag tttgaggaat ttgatccttt tatattcgat ggtgaagaaa tcgaccttat
     1741 tgatataata gaacagacat tagattttaa tgtacctcat aaagttcttt gtagtgaaaa
     1801 ctgtaaaggt ctttgtcaag tatgcggggc aaacttaaat gaagaagagt gttcttgcag
     1861 tgaaattaca aacgatgagg aatacataga tcctcgtttt gctaaattaa aagatttatt
     1921 taattaaatt ttgactaagg aggtggcgta aatggcagta ccaaagcgta aaacgtctaa
     1981 atcaaacaca aaaatgagaa gagcagctaa ctcaaagatg gaagcaacag gatttgtaag
     2041 ttgcccacaa tgtcatgagc caaaattacc acatagagtg tgtccagact gtggatatta
     2101 taaaggtaaa gaagttgtgt ctaagtaata gcttctaaaa agcatgtaga gtatactcta
     2161 catgtttttt ttgtacatat aaaaaaataa gatgatttac tagagaaaat aagtggattt
     2221 tatgcatatt aaaaaataga aaaataataa tataagtatt gaaaattttt gtgtgttact
     2281 atatactact attagtagct ggtactaatt acagctataa aatttggagg gaacatgaaa
     2341 aagaaaagta aagcccaaag acaaaaagag cttatagata tgctaaagac agatcctttt
     2401 tatactgatg aagaattatc aagtctgttt gatgtaagta tacagaccat aagattagat
     2461 agaatgagtc taaacatacc agagctaaga gaaagagtca aatcaatagc agaaactcag
     2521 agttcaaaag taaagacttt aggagtaaag gaaattacag gagaaatcat tgatttatct
     2581 gtagggcgat taggtatatc tatgttagaa gttacacagg acatgattta ctctaagact
     2641 aatactttaa aagatacgta tattttttct ctagcagatt cattggcaat ggctataata
     2701 gatgcaccta aggttattat gagagttgca aatgtaaaaa gttttaagtt gatagaacaa
     2761 caagatagac ttatagcaaa agcagaagtg tatagaaata tagataaaaa gcattatgta
     2821 aaagttgtta tcaacaataa agcccaagag caaatattta gaggaaagtt tatctttgaa
     2881 gaattagatt aggagggaaa ttatgaaaat agtaattgat ggaatgggtg gagataatgc
     2941 acctaaatct aatgtagaag gcgcagtaaa tgctataaaa gaatatcagg ttgatttaat
     3001 aatcacagga gataaagatt tacttgaaaa ggaattttca aattatgaat ttgatagaaa
     3061 taaattagag atagttcata ctactgagat tatagaaaac gaagataaac cagtaaaggc
     3121 tataagaagt aaaaaagatt catctatggt agtagcatta aatcttgtaa aagaaggaaa
     3181 ggcagatgct ataatatcag ctggaaatac aggagcctta cttgctggtg gattatttgt
     3241 tgttggtaga ataaaaggaa tcgatagacc ttgcttatgt tcagcaatac caaatgtaaa
     3301 gcgaggaatg acacttatag cagactgtgg cgcaaatgca gattgtaaac ctaagaatct
     3361 agttgaattt gcagctatga gtaatattta ttcaagaaaa gttttaggtc ttgaaaatcc
     3421 taaggtagca ttagcaaatg ttggactaga agaaggcaaa ggcaatgatt tagtcaaaag
     3481 gtcatatgaa gaaattaaaa aattagattt aaattttata gggaatgtag aagctagaga
     3541 agttataaat gcatacacag atataatcat atgtgatgga tttacaggta atatattact
     3601 taaatctgct gaaggtgtag cactttcagt tatgagtctt ataaaggaaa cttttatggc
     3661 cagtacaaaa agtaaaatag gagcattact tataaaggat gatttaagaa aattaaaaag
     3721 ttttatagat tattctgagt atgggggagc tccactttta ggtctaaatg gaggagttat
     3781 aaaagctcat ggtagttctg atgctaaagc tataaaaaat gctataaatc aaggaataaa
     3841 attttcaaag ggaaaagtcg ttgaagatat taaccaattt ataagcaaat acaatgaaga
     3901 aaataaaaat aacgaagatg aataaactcg ttttggaggt ttaatatata atgaatacaa
     3961 aggctggaat attaggagta ggaagttatc tacctgagca atcatatgat aattttcact
     4021 tcgaaaaaat aatggataca tcagatgagt ggataagtac tagaactggt attaaggaaa
     4081 gaagatttgc caaagagtct gaagcaactt ctgacttagc atctaaagct gccttaaaag
     4141 ctatagaatg tgcaaagtta aacgtagagg atatagagct gattatatta gctacaatta
     4201 ctcctgatat gtctttgcct tcaactgcat gtatagtaca agatgcaata ggagcagtga
     4261 atgctactgc atttgatata tcagcagctt gttctggatt tgtatatgga gtaactattg
     4321 caaagcaatt tgtggaaaca ggttgctata aaaatgtgct tgtaatagga gcagaaactt
     4381 gttctaagtt tttaaattat gatgatagaa caacagcagt attgtttgga gatggagctg
     4441 gagcagctgt tattggtcct gtaaatgagg gtggaatact gtctacacat atgggctctg
     4501 atggtaaagg aaaagattgt ttaaaagtac ctgctggagg ttcaagactt aaggcaagta
     4561 aagagactgt agaagctaat ctacatacaa tagaaatggc aggtagtgat gtgtttaaat
     4621 ttgcagttag aaagatggca gaaacttctt taagagctct tgaaaaagca aacctaaata
     4681 caactgatat agactactta gtgccacatc aagctaatat aagaatcata caagcttctt
     4741 ctaagagatt agagcttgat atgaaaaaag tttatgtaaa tatagacaaa tatggaaata
     4801 tgtctgctgc atctatacca gtagcattag atgaagctta tagagaaggt aaaattaaaa
     4861 agggtgataa tgtagtttta gttggctttg gtggaggtct aacttggggg gcttcagttg
     4921 tcaagtggac tttatagtat aaaatatcta aaatgattta attaacaaaa ttaaacttat
     4981 acacaaaata aagttgatta ataataaaaa gtttactttt atgatttcaa gtgaaggaga
     5041 attgtatgaa taaaatttgc aaaatattaa atataaaata cccagttatc caagggggaa
     5101 tggcatgggt agctactgca tcattagcaa gtgctgtatc taatgcagga ggacttggca
     5161 taatagcagc aggaaacgca ccaaaagaag ctataaagaa agaaattgtt gagtgtaaaa
     5221 aattaacaga taaacctttt ggagtaaatg taatgcttat gtcgccattt gttgatgata
     5281 taattgattt gattatagaa gaaaaagttc aagttattac tactggtgct ggaaatcctg
     5341 caaaatatat ggatagatta aaggaagctg gaacaaaggt tattcctgta gtacctacaa
     5401 tagctttggc acaaagaatg gaaaagttag gagctacagc agtaatagca gaaggtactg
     5461 aaggtggagg acatatagga gaacttacta ctatggtctt agttccacaa gttgctgatg
     5521 ctgtaaacat acctgtaata gctgctggag gaattgtaga tggtagagga attgcagcat
     5581 catttgcatt aggtgccagt gcagttcaag taggaactag atttatttgc agtgaagagt
     5641 gttctgtgca ttcaaactat aaaaacttag tactaaaagc aaaagataga gatgcaattg
     5701 taacaggaag aagtactggt catccagtaa gaacattaaa aaataaacta tcaaaagaat
     5761 ttttaaagat ggaacaaaat ggagctactc ctgaagaatt ggataaaaaa ggtacaggag
     5821 ctttaagatt tgcaacagta gatggagaca tagaaaaagg ttcatttatg gcaggtcaaa
     5881 gtgctgctat ggtaaaagaa ataacacctt gtaaggaaat tatagaggct atggtaaatc
     5941 aagcaagaga gattatgcca gcaatagaac tgtaaatcag gaggagcaag atgggaaaag
     6001 ttgcactagt attccctggt caaggagctc aatatgtagg tatggccaag gatttatatg
     6061 aaaataatgc tgttgctaaa agtgtaatag atgaggctag tgatgcctta aatatggatt
     6121 taaaaaacct tatgtttaat ggaaatgaag aagaactttc taaaactgaa aacactcaac
     6181 ctgctatggt tacacatagt gtagcagtat taaaagcggt acaagctcaa atagatttaa
     6241 aatataatgc atgcttagga ttatccttag gagagtatag tgcgttggtt gcagcagatg
     6301 caattgactt taaagatgct gtatgtttag ttaaaaaaag aggtaagttt atgcaggaaa
     6361 cagttccagc aggtgttgga gctatggcag caattttagg tttagataga aatgtacttg
     6421 aaaatgtggt taaagatata caaggaggta ttgtagaagt agcaaattac aattctcctg
     6481 gacaaatagt tatatctggt gaaaatgaaa agatagaaga agcaatggta aaatgcaaag
     6541 aagcaggagc aaaaagggca gttaaattaa atgtaagtgg accttttcac tcatcaatgt
     6601 taaaagaagc tggtgtaaaa ttggccagtg aattagaaaa agttaacata actaaaccta
     6661 aagttgatgt ggtggcaaat gtaaatgcag attactataa aaacgaaggt aaagacctgc
     6721 ttataaaaca agtaagttca tctgttcttt gggaagattc tatagaaata cttttaaatg
     6781 atggatatga tacttttata gaaatgggac ctggaaaaac tttaaaagca tttattaaga
     6841 agatagcttc caataaaaaa gcaaatgtca atatttataa tatagatggt atagattctc
     6901 ttaatgaatt tgtacaaaat tatagaaatg gagagatata atgataaatc ttacaggaca
     6961 agtagcagtt gttactggtg gctctagggg tataggaaaa gaaatagcaa aaaaactagc
     7021 atcttttgga gctgatgtag taatcaatta tacttctaaa gaagatgaag cactaaaaac
     7081 taaaaatgaa atagaaagta tgggggtaaa gtgtacctct ataaaatgtg atgtgtctaa
     7141 atttgatgaa gtgaatcaaa tgatagattc tgttgtaagc gaatttggaa aaattgatat
     7201 attggttaat aatgcaggca taactaaaga tggtctgctt atgagaatga aagaagaaga
     7261 ttttgataga gttatagata taaacttaaa aggtgtcttt aattgtacaa aagcagttac
     7321 taaacctatg atgaaaaaga agtatggaag aataataaat atgacttcag tagttggaat
     7381 tatgggtaat gcagggcaaa ctaattattg tgcatcaaaa gcaggtgtaa ttggatttac
     7441 aaaagcttct gcaagagagt tagcatcaag aaacataaat ataaatgcag tagcacctgg
     7501 atttatagaa acagatatga ctagagtact aagtgatgat gtaaaagaat caacactagc
     7561 aaacatacca aagaaatctt atggtaaacc agaagatgta gccaatgccg tagcattttt
     7621 agttagtgac atgtcaagtt atataacagg acaagtaata aatgtagatg gtggaatggt
     7681 aatgcaataa taatttaaaa agtagagaaa tctattaaaa taaaaaattt taggaggtac
     7741 acaatgttta ataaagttgt agaaataata atagagcaat taggagtaga agataaagaa
     7801 ataactatgg agacatcatt aatgaaggat ttagaagcag attcattaga tgcagtagaa
     7861 ataataatgg cacttgaaga tgaatttggt atagaaatac cagatacaga agcagaaaac
     7921 ttcaaatcta taggagatat agttaagtat atagaagcta ataaatagtc gagctttaaa
     7981 aaagtggagg tatccgatga ataaaagagt agtaataaca ggacttggat gtgttacgcc
     8041 gttgggaacg ggaaaagaag agttctggag taatataaaa tctggagtat ctggtataga
     8101 taaaataact aattttgatg ctagcacata tcaaactcag atagcaggag aagttaagaa
     8161 ttttcatcca gaagaatata taagtaaaaa agaattgaag agattagata aatttgctca
     8221 atttgcaata gtatctgcta aattagcagt tgaagatgca aatcttgatt tagataaagt
     8281 tgatagagaa cgttttggtg ttataatagg ttctggaata ggtggagttg aagctataga
     8341 aactcaacat aaaattcttt tggaaaaagg aaataaaaga gtaagttcac tttttgtacc
     8401 tatgatgata ggaaatatgg cagctggtca agtttcaata tttttaggag caaaagggcc
     8461 taacactaat gtatgtacag cttgtgcatc aggaactcat tcaataggtg atgcttttaa
     8521 ggtaattcaa agaggtgatg cagacatcat ggtagcaggg ggctctgaag ctgctgtaac
     8581 aggtcttgct tttgctggat tctgtaacat gaaggctatg tcaactagaa atgatgaccc
     8641 taaaactgca tcaagaccgt ttgataaaga cagagatggt tttgtaatgg gagaaggagc
     8701 aggtattgtt atcttagaag acttagaaca tgctttagca agaggggcta aaatatatgc
     8761 agaagtagtt ggatatggtt taactgctga tgcataccat atgacaactc cagctgaaaa
     8821 tggagaggga gcagctaggt ctatgaatat ggctttgaaa gatggaaatg ttccattaga
     8881 agaagtagat tatataaatg ctcatggaac ttcaacttat tacaatgatt tatatgaaac
     8941 tatggctata aaaactgtat ttggagaaaa ggcatatgac ttatgtgtgt catcaacaaa
     9001 atctatgact ggtcacttat taggagcatc aggtgctata gaggctgttg tttgtgctat
     9061 gagtatagaa gatagttttg tgcctccaac tataaacata caagaagttg gtgaagattt
     9121 ggatttagat tatgttccaa atcaaggtaa agaaaaaaat attagatatg cactatcaaa
     9181 ttctttagga tttggtgggc ataatgctac aatagtacta aaaaaatatg tataaataaa
     9241 tattaaatat aaaactaaaa aacaagcact tgttttaact gtataaattt atattagctt
     9301 aaatttaaag tctcctaaat tattttagga gactttttta ttaagattta agtctagcat
     9361 atgttgtaaa tcattttgat atattgtatt attaattatt aagaggttat ttatatatgc
     9421 aagttttcat tctacaatat acaaaaggag gactaaaatt ttgaatttta gactaccaaa
     9481 gaaaaggtta cccaaaaaga taatttttat atgtataata cttattagta ttattttgtt
     9541 tataaagtat gaccaaaatg gattgaaaga aagagaaatt ataaataagg gaaaatatat
     9601 gtctgaaagc cttgtggcag ataaggagta tgatgaagca aaaaaagtgg ttaagacttc
     9661 tttcgaatct attccagaaa aaaaatacaa taaagtatat aatgaagttt gggatatgtt
     9721 aaagactatt tcatatgttc cagatggaac gaagatagtc attgattctt tagaaaagat
     9781 gagagaatca gatgtgaaat tatctgatga atgtagattt aatatagaaa aaagattagc
     9841 atcagtgtat ataatggata ataattattc taaggcagta gatttaactg taaagtctat
     9901 aaaattggct gagaaattgg ggaataatta tgaaaaagca agactagatg ttgatttggc
     9961 gagcatattt ttaaatatag gtagctatga aacaggagag aaattaataa aggattcttt
    10021 taaaatagat attgatgaag gtgaaaaaaa tggaatggtt agattatatg ctattataaa
    10081 tctagcagaa atatatgtag aagagggaga atatgataaa gctattgaaa taagtagcag
    10141 gataaaagat tataaaaagt ttgtaaatac ggataattac aatgattttg atataatggc
    10201 ctctataatg aagtcaaatg cgtatgtggg caaaaataat atacaaaagg caaagacttt
    10261 tttagaaaaa gctgattatc ttataaaatc agatagaaca gtttatatat tagataaaga
    10321 tatgtactat tatatggcaa tgggaaactt agaatataaa agcgaaaatt ataattctgc
    10381 aatagataat tataaaaaaa gtttagagat atctaccaaa agaaagttaa ctcaggagaa
    10441 aataaaaaat ttaaataaga tattaaatat atatgaaaaa caaggaaata tagaatcttt
    10501 aaatgagtat caaaagatgt taataaatga atataaagag aacaaaagta taagagattc
    10561 agagactagt ttctatataa ttgataaagt atcaaacgaa agtaagctat ttgaaaaaac
    10621 taaaaaagaa ataaaatatt ataaaatatt atttacagta attttaattg ctatattagg
    10681 gtctactttt ttatacaacc gattgaagta ttttaaagca caaaatttac atgatggtct
    10741 tacaaatgtt tataatagaa aaagttttga tattatgtat gaaaagtaca gagagaaaga
    10801 tgataatttt gcacttgtga tgatagatat tgataatttc aagctcataa atgataatta
    10861 tggacataaa tttggtgaca ctgttataaa gggaataaca aataccattt gtgttatgtt
    10921 agaacaagat gataaagtct ttaggtacgg aggagaagaa ttttctgtat taataagaaa
    10981 taaatctggt gaggaagtag cagatataat tgacaatata agggttgcaa ttgcaaataa
    11041 aaagtggaat gatgatgtga ctgtgactat aagtgcaggt gtagctcata tttcagatag
    11101 caaagatgta ctagaagaag ctgataaaaa tttatataaa gcaaaacaac ttggtagaaa
    11161 taaagtagta tataagtaat tatatactat ataaataaga ggtataaata tgaaacaatc
    11221 aatagctata gtaactgata aaataactaa actatcatct ttcttagaag aaaatatacg
    11281 tttggtttta ggtaattata ttgatataaa ccactattat ctggaagttt taaaagagaa
    11341 tgataaaata caaggtgatt ttgtactagt aatgaatgat gatagattaa acagtatgag
    11401 aaagcattta gtacaagata gtaagattat agtgataagg agaacactta aagaaaatga
    11461 aatatatgga ttattttcaa taccaaatgg aactgaagta ttggttgtaa atgatacaaa
    11521 agaaactacc ttagaaacga taagcttatt ttacaaaata ggagtaaaaa atttaaagtt
    11581 tactccatat attgaaggaa aaatttataa aaatatagac atagctataa cgcctggagt
    11641 aaaggaaaaa gtaccaagtt atataaataa agtaatcgac cttggtaata gatatattga
    11701 tatatctact tttatagaaa taataaatgg tcttagaatt gatgttaaag aaatacgtaa
    11761 aaatttaatg gcatattctg agagtttaat aagtttagat aatggagtta aagataatta
    11821 taggcaactg tttttaaaaa tagaagaaca agatgttata ttgaatctat caaaagatgg
    11881 aataatattt acttcagcag atggtataat aaacacattt aataaagaag ctttaaaaat
    11941 tttaggtata aatgaaaatc cacaaggcaa aaacatagaa gatatcattt ctgaagattt
    12001 aaatatttta cttgaagaca aagaaataat tgatgaagtg gtatttacaa ataaaaaata
    12061 tataaatgta aataaaaaaa gtattttttc tatggggaat aaagctggga tatattataa
    12121 cttacaagaa ataacgtata taaaaaaatt agaacaaaat cttactaata aattaagaga
    12181 acaaggtcag atagcaagat atacatttaa agatataaaa actaaaaata aaaatatggt
    12241 aaagtgtgta gaattggcta aaaaaatatc taaatcagac ctttctgtat taataatagg
    12301 agaaagtggt actggtaaag aattattatc acaatcaatt cataatgctt ccaatagaag
    12361 taatcaacca tttatagcgg ttaattgtgc agcagttcca gatagtctat tagaaagtca
    12421 actgtttgga tatgaaaaag gctcttttac aggagcttta agagaaggaa aaaagggtct
    12481 atttgaactt gctaataatg gaactatatt tctggatgaa attggagata tgcctccatt
    12541 gctacagaca aagttactaa gggtattaca agaaaagcag gttatgccta taggttccca
    12601 taatgttata aacatagatg ttagggtcat agcagcaaca aacaaaaact tactaaagat
    12661 gattagagaa ggaaaattta gagaggacct gtattataga ctaaatgtat tgccaataga
    12721 tgtaccatca ttgaggaata gaaaagaaga tataataaca cttatgaatt tctttttgaa
    12781 aaacaatgta agactttcgc cagaagttat aactatttta gaaaaatata attggccagg
    12841 aaatataaga gagttacaaa atgttgcttc ttatgtaagt ctaatgtgtg atagtatggt
    12901 ttttagagat gacttaccac catatataag ggtagaatgt gctaacaatt atgaagatgg
    12961 atttggttat acaaaaaaag aatttgagga aatactgagg attctatatg aaagaagaga
    13021 gtcatcctct ggagttggaa gagggtttat aatcgaaaag cttatacagg aagggattga
    13081 gatttctgaa agcaaagtta gaaaggtgct atcttattta agtgaatgtg gatatatatc
    13141 atctaaatct ggtagaggag gaagtcaaat aacctcagag gggataaaac tttataataa
    13201 tataaattaa gctaagtatt tgatattgaa atcacatatt ttgaatttag atatttaaat
    13261 aataaacttt tatatttata gagattaatt tatactatgt cagaaagaat attgtaattt
    13321 ataattaaat attaataggt ttttaaaata ggattagata ggtaataggt taagttagaa
    13381 taacccatta cctattttta tttgtaagaa aagtgtacat agagttaaaa gtaaaaaata
    13441 caactaataa aactattgaa aacactagat aaataataaa taaaaataat tataaatttt
    13501 ggcatatata ttgctaatca tagagataag acgacaaaat aattgggagg tttaatgatg
    13561 aaatacaaaa caacagggac ttgtgctaca gaaattgaat ttgaagtaaa agaaaataaa
    13621 gttacaaatg taaactttat aggtggatgt gatggaaatt taaaagggct aaaagtatta
    13681 gttgaaggca tgaatataga agatgtaata caaaagttaa aaggaataga gtgtaaaaca
    13741 aagccaacat cttgcccaga ccaactgtct ctagcattgg aaaattatat gaatataaag
    13801 taatacataa aacaatcgat tagttaggag tttaattatg aaaccaataa tagggatttt
    13861 aggaaattta ataataatgg aaaatggtat gtttccaggt cttgaaaggt catatgtaaa
    13921 taatgattat ataaatgcag tgctaaaagg tggcggtagt ccagtaataa ttcctgtaaa
    13981 tacagataaa gaagttataa aaaaacagat tgaaatggtt gatggagtct taatatctgg
    14041 gggatgggat atcaatcctc aactgtatgg agaagaaaca agagaagaaa cgacatttat
    14101 atatccagaa gtggatgaat ttgatttaat tgcaataagt atagcattag aacttaaaaa
    14161 gcctatatta ggtgtatgta ggggactaca aattttaaat gtaagtttag gaggaacttt
    14221 atatcaagat aataatctta tagaaggaag ttatataaaa catacacaat cttctaaaag
    14281 acatgtagct actcataaag tcgatgttaa agaaggaagt attttagagg gaattttagg
    14341 aaaacaatta cttacaaata gttatcatca tcaaagtgtc aatcagcttg gaaaaggatt
    14401 aaaagccata gcatactcaa aagatggtat aatagaagct attgagaaag aggaggaaaa
    14461 ttttgtagta ggagtacagt ggcatccaga aatgatggta gattactgtg ataaaatgga
    14521 aaaactattt aaatatttta taaatatttg ttcaaattta taatatacct tggggggatt
    14581 gaacatgaac gaaaagaaca aaatgggatt aataagtatt atacttttag gtattaatgc
    14641 agtagtagga gctggagttt ttctattacc aggagatgca atgaaatcat ttggtgtagc
    14701 aagtatattt gtatatatat ttgatatgtt gttagtttta tctatggcat tctgttttgc
    14761 tgaggttgca ggtaaattca ataaaaatgg cgctgcctat gtatatacca aagaagcttt
    14821 tggagatttt tgtggttttg aagtaggtct tatgaaatgg gtaataggat gtatttcttg
    14881 gggagcttta atagtaggtt ttcctacatc attatcagca gtatgggctc cagcaggtga
    14941 accacatata caaaaaatta taattgtagc catgatagtt gggcttacaa ttataaactt
    15001 attaggtgta tctctatcaa aaattgtaca aaatgttata actgtaggta aactaattcc
    15061 attaatacta tttataggaa taggtatatt ttttataaaa ggagttaatt ttacttcttc
    15121 aacaatggta cctccaggag ctggagcaac agagtttgga gcagcagcac ttttaatgtt
    15181 ttattcattt acaggatttg aatctatagc agttgcagca gaagatatgg aaaatccaca
    15241 aaaaaatata ccaatagcaa ttataagtgt aatagtaatt gcatcaataa tatatatatt
    15301 aaatcaagtt gtatgtgttg gtatactagg agattcgtta tctagtacat ctacaccagt
    15361 ggcagatgct gcaagaatat gctttggaaa tatgggagct ggattggtta cctttggaac
    15421 attggtttct gttggtggaa tttgtatgtg tggtgctttt gtaaatccaa gaagttgtgt
    15481 agctttagct gatgataaaa tgttaccaag aatatttgca agaaaagata aaaaaggtac
    15541 accatatgta gcgataatag ctactatgtt aatcactata ccaatagctc tatctggaag
    15601 ttttgctgaa ttagcagcaa taagtgcagt tgctagattc atacaataca taccaacatc
    15661 tttatccgta ttagtgttta gaaagaaaag accagaatta gtaggtactt ttaaaactcc
    15721 ttttggagca gtgattcctc taattgctgt atgtgttgga acatggttgt tattccaagc
    15781 atctatgcat caattaatta tgggattagg agctttggca attggagtac cattatactt
    15841 tataatgaag tcttataata gaaaagtctg tggtgaaaat ttaaagaaaa tagtttaatt
    15901 atgttataag aatttattga gttaaaatta gacattggca gaaaattaaa tacaaataag
    15961 tatctataag gctatattaa aatattatta attttttatt ttaatatagc cttatattgt
    16021 tatcaataaa tgaaaaatat tgtaacaaca gaagaacaat agtattatgt ttatagataa
    16081 aaaacttatt aggaggtaaa tttatgccaa caataacatt aaaaaatggt gtagacgtac
    16141 ttattagaga aggtgtaaga gaagatgctt aaagcattat agatttttat aatgaagtgg
    16201 gtggagaaac tcattttctg tcatttggaa aggatgaata taaaatatct ttggaggaac
    16261 aagaaaatgc tatagaatca gcaaaagcat ctgataattc tgttaaactg attgcattta
    16321 tagatgatga aatagttggg attgcaacga ttgattctaa tcaaaaagca aaaggaaagc
    16381 atgttggagt attaggaatt gttgtaaaag aaaaatattg gggaattgga ttgggtaaaa
    16441 ggcttatgtt agaccttata gaatggtgta aatcaaatgg aataaccaag aagataactc
    16501 ttgtcactaa tgaagaaaat tataatgcta taggattata caaaaaagtt ggatttgaag
    16561 tagaaagcat actaaaaaaa gaatgttatt ataatggtgt ttatactgat ttaataggaa
    16621 tgtcactttt attgggaata taattagtgt acattttatc tcgaaaaaag tatattaagt
    16681 atggtataat taaaaaagaa tataacttaa tataattttg gaggacgaat tatgaaaaat
    16741 ctgtgtaaaa tatcagatga ttatttaaac agcaagctta agtatttaaa gttattatca
    16801 aaacaatatc caagtatatc aaaagcaagt acagaaataa taaatttaga ggctatatta
    16861 aatcttccaa agggaacaga gcattttata acagatgtac atggtgaata tgaaccattt
    16921 gtacatgtat taaaaaatgg ttctggtgta ataaagagaa aaatagaaga attgttttca
    16981 aatacaataa gagacagcga aaaaaaaatg ttagcaactc ttgtatatta tcctgaacaa
    17041 aagttagacc taataattaa gcaagaggaa aatatagatg atttttatag aataaatatt
    17101 tatagactta tagaactttg taaatatgct tctagcaaat atactaggtc taaagttaga
    17161 aaactgttac cagaaaattt taaatacata atagaagaac ttttgcatga gcatgttaaa
    17221 agtgaacata aagaagagta ttataaaagt atagttgaaa caatagttga cataggaata
    17281 gctaaggagt ttataattgc tatttctaca gttatacaaa aattggttgt agatagactt
    17341 catgtaatag gagatattta tgatagaggt ccaagaccag atataattgt cgataagctt
    17401 attgaacatc attgtgtgga tattcaatgg ggaaatcatg atatattgtg gatgggtgca
    17461 gcctcaggtg aaaaaacttg tatagcaaat gcactgagga tatcagctag atatgcgaat
    17521 ttagacattg tagaagacat atatggaata aatctgttgc ctttagccac ttttgctata
    17581 gaaatgtata aagatgaccc ttgtaaagaa tttattccaa aggttaatga ccaaagtgta
    17641 acaacaacag aaaagtcttt aatggcaaaa atgcacaaag caataagtat aattcaattt
    17701 aagcttgaag gtgaggttat aagacgaaga cctgaatttg aaatggaaca tagacttttg
    17761 cttaatatga taaactatga tgaaggtacg attactttaa aaggtaaaac atataaatta
    17821 aaagatactt atttacctac aatagacaaa aaagacccat ataaattaac tatggaagaa
    17881 agaaatgtta ttgataaatt agtatcttca tttagaggta gtgaaaaatt acaaaaacat
    17941 gtttcatttt tgttttctaa aggaagtata tatttaaagg ctaactcaaa tttactgatt
    18001 catggatgtg taccattaaa tgaagatgga agctttatgt ctatgaatat aatgggaaaa
    18061 gagtataaag gtaaggctct tatggataag atggagtctc tagcaagaga aggatttttc
    18121 tttaaagata aggcagaaga aaaactatat ggtatggata ttatgtggta tttatggact
    18181 gggaaatgtt catcattatt tggtaaagat gatatgacta catttgaaag atactttata
    18241 gaagaaaaag agactcataa agaaaataag aatccatatt ttaaacttag agaaaatgag
    18301 atggcttgta aaagattatt tgaagaattt gatttagagc ttgatgaatc ccatataata
    18361 aatggtcatg ttcctgtgga gagtaaaaat ggagagagcc caataaaagc taatggtaaa
    18421 attctcgtta tagatggtgg tttttctagg gcttaccaaa aaactactgg tatagctgga
    18481 tacactttga tatacaattc tagaactttg caattagtat cgcatgaacc atttaattct
    18541 gctgaagaag ccattgcaaa tgaaagtgat atcttatcga caactgttgt agtagagcat
    18601 aaggcaaaga gaaaaatggt gagagatact gatgaaggag taaaaataca agaggaaata
    18661 gaagatttaa aactactttt aatggcttat aagaaagggc taataaaaga aatgtagata
    18721 ttatagaggc acttcataat tgaagtgtct tcttgttaat acttattaaa tatattataa
    18781 agattaataa tagtagttta tattatactt actaagtgaa tccaagataa atgggttcac
    18841 tttttttatt tataaacatt attaaaaaaa tatagatgtt ttggttatat tccttgtcct
    18901 ttataaatag aattatataa acaaaggagg aggacaagag atgaataaac tttctgatga
    18961 aataataaac tctctttcta caactataag agaaaaggta gaaaaagtct caaacaataa
    19021 tctgaacata gaagaaatta ggttacgctc acaaaaacca ttgatactaa atgcaaactc
    19081 taaagattat ttttacaatc aaaaaactat gacacttgat ttaaatcaac aaaactcata
    19141 tgtagtaaca agagaagatg tagagcaaac ttttcaaata atatgtaaat attcaataca
    19201 ttcatttatg gatgacataa aaaaaggatt cataactttg agaggaggtc atagagtagg
    19261 gttagttgga aaagcaatag tagaagatgg acaagtcaaa aatataaagc atatatcatc
    19321 tttaaatata agggtatcaa gggaaattat tggatgctcg gataagattt taagtcatat
    19381 tataaaggga aaaaatcaga ttaataatac tttgataata tcaccacctc aatgtggaaa
    19441 aacaacttta ataagagata tagtaagaaa tttaagtaat ggtaatgaag attatggatt
    19501 taaaggttta aaagtagctt tggtagatga gcgtaatgag atagcaggag cttatctagg
    19561 tgttccacaa atggatgtgg gaataagaac tgatataata gaaacttgcc caaaagattt
    19621 gggtattacg atgcttttaa ggtctatgtc accaaatgtt attgtgacag atgaaattgg
    19681 gagtgaaaaa gaaataaagg cattatacac agcattaaat ggaggtatag gattaataac
    19741 tactgtgcat ggagattcaa tagatgatat acaaaataga aaagaattaa atagacttct
    19801 ggataaagag ttatttaaaa aggttataat tctttctgca aaaagaggag caggaacgat
    19861 tgaaaaaatt tatgatttag aagaaaagag atggtatttt gcaaattaaa ataattatta
    19921 tagctctctt ggtaggaagt agttatttga taggtgaaca aatatacaaa acttatactc
    19981 gtagacataa acaattaaac gatttaataa gagttttaga aattttgagg atggatttat
    20041 ctttcggact ttatacatta gaagaaatct ttaataggat aggtggaaat aaagagtttt
    20101 gtttttggaa atttttctat caaatatcag aaggacttca caatgaacaa agtaaaactt
    20161 tggaaataat aatatcagaa aatattgatg tcttaagtaa agaaacttat ctaggcaata
    20221 aagaaattga ggaactgaaa aatctaatac ttactttagg gaaaagcgat atagagtcac
    20281 aacaaagaat gatagattta tctatagaaa atttgaaaaa acaaacctat gagacaaagg
    20341 aagatataaa caaaaaaggc gtattgtata aaaaattagt gacattcata ggtataggta
    20401 tatgtattat attgatttaa tatggggagg tttattatgg aaatatcatt gatattaaag
    20461 gttgcaggtg tcggtattct aatatcagta ttgaatatga tattggaaaa aacagataga
    20521 aaagattggg caggtcttac tacattagca ggtgtaataa tcgtattggg tatggtaata
    20581 acagaaataa gtgacttgtt taatactgta agaacaatgt ttcaacttta ctaaaaagga
    20641 gggagtaatt tggaaataat gcaattaata ggaattgcaa tcatttcaac tacactctgt
    20701 ttagtaatta aaaaagatag accagagata gcaaatttca tagcaataat aactggagta
    20761 ataatactat tgtcagttat gtttaagcta aattttatag tagatagtat acaagatttg
    20821 gctaacaagg ctaacatacc gactatgtat atatcattaa taataaaatt aattgggata
    20881 gcatacttaa tggaatttgc gatacaactt tgtaaagatt gtggggaagg aaacattgct
    20941 tcaaaactag aatttggagg taaaataata gttatgtcaa tgtctttccc tatacttttg
    21001 tccattgtag aaatggtggt gaatataatt ccatagatgt gtatcttgga atgaatataa
    21061 gtatattaga gaactttcgt tgtattgagg tttatagagt gaagagaggc atggttgctt
    21121 atgaaaaaaa gatttttacc aatgattata ggttttttat ttactttctt ttttgtaaat
    21181 atctttgcta ttatgatatt tgctaatgaa gtaccaagta gtgaagataa agaatatggt
    21241 gaaacaaaaa atagcataga taaatatata gatggtcaat tagacaagct agatataaat
    21301 gagattcaag actatataaa taaagaaata gttattaatg atgttaattt aaaatcattt
    21361 gtaaaagatt taattagtgg agaaaaaaat atcttagatt tattcaataa agatggattg
    21421 aagatattga tgtttgatga atttaaagca agtttaaagg tagtagcagt aattttggta
    21481 ctggctctgt tatcatctat tttaaagagt ctggaaaact ctttttcatc aggtgcagta
    21541 agtcaaatag caacatatat aatatttatc acaatggtat cacttacact tattggtttt
    21601 aaagatgtat tacagatttg ttatgatgca atagaccata ctgtaggtct tatgcaagtt
    21661 ataatgccaa tattaataac atttttactt ttaattgggt tcccaataac gtcgactact
    21721 ttgaatccta tcttcatagg aggagtaaca tttataaatg tattttttaa aaattttcta
    21781 tttgtatcta ttactgttgc atttggaatt ttaataataa acaatttatc aaaaaatata
    21841 aggctaaaga gatttttctc ctttgtaaaa caaataaatt atgtttctat tggagctatg
    21901 tttactgttt acttaggtct tgtatccata caaggattgt atgtaaccag ttttgataaa
    21961 ttcagtgtaa agactgctaa atttgctata ggtaatttta ttcctgttgt aggtggattt
    22021 gtatctgact ctgtggatat tttattatct tcatctcagc ttataaaaaa tatatttgga
    22081 ggaatagggc ttatcttact tgttggaatt tgtttacttc cagtaataaa aattttatca
    22141 gtaatagtag tgtacaaatt agcagcaata attgtagagc ctgttggaga ggatggaata
    22201 tctaattttt taaatgaagt ggcaaattta atgataataa tgctagcatc agtaattgct
    22261 ataacagtaa tgttctttgt aactgtagct atcttgacct cgataagtgt cgtaagtcaa
    22321 gggtaattta tatatcagtg aaaaataatt acatttaatc taatgttttt agagaggagg
    22381 atgctatgtt agagggcata aaggcatgga tagttagtgt tttgatagga gcatttatag
    22441 taaatatagt agatatgatt ttaccaagtt ctaagataaa accttatgtc aacctagttt
    22501 taaactttat gtttgtattt attgtaataa ctccagtagt aggatttttt tcaaaagata
    22561 tgagtttaga agatagaata ttaaaatcta tgggaaacta caacaagcag tatgtagata
    22621 gtacaaatgc tttggcaaaa gagactggaa ataatagtct atccaaggga tatgaggatg
    22681 ggttaaaaga agtacttaaa ttaaaacttg atgaatatgg ttatgattta gaagatatag
    22741 agcttaatgg ggcaaatata aataatataa aaataaaaga aaagaataat agtgcaaaaa
    22801 gtaataacag ttccaatgaa gaaaataaaa ataatagtac taaaagagag gaagaaaaca
    22861 taaactctaa tgacaaagaa aattctaaac aagtcttcaa aaaaggtaca gagtatgggt
    22921 tgaacctaaa tgaagaaaaa ttaaaaaacg acttaataaa ggtgctggat gtttctatag
    22981 aagatataca aattgataaa taggagttgg gagaatgttg aaaaacttaa atgacaaaga
    23041 taagagaaag gtatattcac taataactat agcaggaata tgtgtggttt cattagtatt
    23101 attatcttgt tttcctagta gcaaaagtga taaacaagtt ggaaaaacag agactaataa
    23161 aaatgctgaa aagcaagtca ctaaaaaaca agaaaaagat gatttagagt caaaattaac
    23221 agcaatacta tctaaaattg atggtgcagg agacgttgat gtaatggtta catttgaatc
    23281 aagtgaagaa atacaacctg cttttaattc aaataataca acagaaacaa cagaggaaaa
    23341 agatgcacaa ggtggagaaa gaacagttac gacttctagt gaaaataaaa caatgataac
    23401 ttcaaattca agtgaccctg tagttataaa aactacagag ccaaagataa agggagtgat
    23461 agtggtagca agtggagcaa gtgacccaag tgttaaagag acactttata gtgcagtaca
    23521 aacatcatta caagtagctg gtcatcaagt agaaatatat tctaaataaa tacatataac
    23581 cggggggata aatgaatgaa gtttaattat aagggaagag gatttgtaat aataacttta
    23641 actgcaatgt tagtggtagt aggaacagtg aattatcaac taagtaagaa atctttatta
    23701 gaaacatcaa aagagtttaa ggcatatgaa gaagcacagt tgcaaaaaaa tactgatgat
    23761 agtgatagta gtaagacaga ggattctagt aatgtagata aacaaggtgg taaggaaagt
    23821 gctgatattg atatagtcga tagcaaagct agtaaagtaa aagaaaaggc aactgagaca
    23881 agtaaggaaa taaaagctca attatcatca gagaaaaata tgaaaaaggc atcttatatt
    23941 ttagatatga aaatgaatag agaaaaacaa agaaatgagt tagttcaaga tttaaatgaa
    24001 atgataaata atccatctac aacagaagaa tctagaaaag aagcttctaa tatgaaatta
    24061 aatatagtta aaattcaaga aaaagaactt caaatagaaa accttttgag tacaaaagga
    24121 tatgaagaag cgttagttta tataagcgat aacaaagtta atgtagttgt aaatgaagct
    24181 aaattagaaa agaaagatgc agcaaaaata tttgatttag ttgcagaaca agccaatgtg
    24241 aagtatgaaa atattaaact tacaaataat aatagtaata agtaaagtat aaacctcaga
    24301 attaactgag gttattttct tgcaaagtag acttgtattt ggtattatta tacttataaa
    24361 aatagttcct taaaatcagg aggtaagttt taatatggaa gataataaat ttggacaagt
    24421 aaaaatatct aatgatgtaa tagctacaat agctggttta gcagcattag aagttgaagg
    24481 catagaaact acagcaacat taacagataa gttgttaaaa aataatggag taaaaataca
    24541 aatcgaagaa gaggatgtta atttagatgt aatggttacg ataaagtatg gaatgtcaat
    24601 accagataca gcttttaaag ttcaagaaaa tgtaaaaaat actgttgaga caatgacagg
    24661 actgaaggtt tctcaagtaa atatacacat tcaaggaatc agctttaaga aggataaagt
    24721 tgataaagaa gaagcaaaag caactaagaa aaattaatat tagccctctg aaaagtcaga
    24781 gggttttttg ctggtaattg attttatatg gataattaaa cttaaaggag aattttgatt
    24841 gatgaaaaaa gatagggcac aaaagagtac aacaagagaa tatataatga aacttatata
    24901 ccaaataaat attaataaag aagattttga aactttagaa gataaagtag ataatttttt
    24961 aaaagataat tcagaacata ttataaatag atataaagaa cttgcacttc aatactcaaa
    25021 aaatacaaat ttaaagttag aagatactga aattgaagat gttatagaca agaaatatat
    25081 aaatacagta tgcaaagcat taaaagaaaa tcatgacaaa atagatgagt taataaataa
    25141 gcatgctaaa aactggacag tagatagaat gccaaaggta gatgtttcta tacttagatt
    25201 gtctgtgtgt gaaatacttt atttagacac tcctaataaa gtatcaataa atgaagcggt
    25261 agaacttgca aaaatatatt gtgatgataa gtctcctaaa tttataaatg gtatattggg
    25321 aagtgttgtt gatgaaattg ggaaataata taataattgg aattgatact agctgctata
    25381 ctacttctat agcagctatc tctttagata agaaagttat attcaatgaa aaaataatgt
    25441 tagaagtaag ggataattca aaaggtttaa ggcaaagtga agctgtattt caacatatca
    25501 ataatttagg gattcttagt gataggataa aatcttttaa agataagttt aatgtagaag
    25561 gagtttgctc atcaaaaaaa ccgagacctg ttgaaaactc atatatgcct gtattcaatg
    25621 taggtcataa ttttggaaaa ttattgtcta gtatatatgg ttgtaggttt tatgagacta
    25681 ctcatcaaga gaatcatatt gaagcaagtt tattaaatag taaattaaaa aataataata
    25741 aatttatttc tgttcatatg tctggtggta ctacagagat acttttaaca agcaaacaag
    25801 atagtcatca caatgtatgt gatactaatt taggtaaaat tgccaaaata agtattaaaa
    25861 aagatgataa aagtaagtta tacaataatt ttggatataa tatagatata attggaggaa
    25921 gtaaagatat tagctttggt caactcatag atagagtagg aattaagctt ggatataaat
    25981 ttccttcagg aaagtatttg gatgaaaatg ctttaaattg taatcttaaa atagaaagtg
    26041 gtctgaaaac ttctgtaaga gatgggtata tgaatttatc tggattagaa aatcaggtaa
    26101 ataagattat aaatgataat ggagataata ctaatcaaaa agaatacata tctaaattag
    26161 tattagattc agtagttaga aatatgttta aatctttagt atatttatgt gaaacttata
    26221 atgtaaatga agtagtattt gctggtggag tttctgcaag taagtatatt cttagagaat
    26281 taagcatgaa gttaagaaaa aagcatatag aagcttattt tacagaacca caatattcaa
    26341 ctgataatgc tgtcgggtgt gctataatag gattgaataa ctttttagga gaaagagtat
    26401 gaaactaaga gctttagata taagtgaagc aaactcatat attaaaagaa ttttaataaa
    26461 cgacccaata ctttctaatc ttaaagttaa aggagaaatt tctaatttta aggttcatag
    26521 tagtgggaat gtatatttat cacttaaaga tgaaacatca aagttaaact gtgtaatttt
    26581 taaaagtaat tttaatcgca atttaaaatt agataatggt gtaaaaatta tagctaatgg
    26641 atatatatca gtctatgaaa gagatggtgc gtatcaatta tacattaatg aaattgaaat
    26701 agagggaata ggaaatttac acatagagtt taatagatta aaggaaaaac ttaataaaga
    26761 aggattattt gaccctaaat acaagatacc tatacctaaa atgccaaact caattggcgt
    26821 tataacatct ccaacaggtg ctgttataag ggatataata aatgtaataa aaagaagata
    26881 tccgaaagtt aatataaagc tttatccagt aatggttcaa ggagataaat cagctgaaga
    26941 aatctgtgaa gcaattagat ttttcaatca tatgaagaat gttgatacac ttatagttgg
    27001 tagaggtggg ggttcaatag aagaactttg gtcttttaat gatgaaatgg tagcaagaga
    27061 ggtttttaat tctcaaattc cgataatatc agcagttggg catgaaacgg attttactat
    27121 ttgtgacttt gtgtctgata tgagagcccc aacgccatca gcagcagctg agattgctac
    27181 tccatcattg gatgatataa actataaact tggaaacata aaaagtagga tgagtaagtc
    27241 tcttacaaat caaatagagc tagaccaata taggttagaa acagtattta ataagataaa
    27301 taactattta gattcgtaca caataaaaga taaagttata caattagaca aaatatatga
    27361 taaaataatt tttggaatag aaaataattt aaaattagaa gatgaaaaat tagtaaaaat
    27421 tggagcatta ctccataatt taagtccatt agctactatg gatagaggtt atagtataac
    27481 tcaaaaaaat ggaaaagtaa taaatagtat aaaaggatta aaaataaagg atagtataga
    27541 tatagtatta aaagatggaa atttagaatg tatgatagat aaaattgaaa ataaagaggg
    27601 atagtatgaa tttaacctac gaagaagctt ataaaagatt agaaagtatt ttaagtgaat
    27661 tagaatctaa aaatgctagc ttggatgaat ctttaagcct atatgaagaa ggtataagcc
    27721 tttataaaca ttgtaataag cttttagatg atgctaaatt gaaaataagt aaatttaatc
    27781 aattaggaat agaagaagac tttaaaatag aggaggaata aaattggaat ttaaacaatg
    27841 tctaaaagaa aaagcaagtt ttgtagaaaa agtacttaaa gaatatatgc ctaaagaaga
    27901 agggtatcaa aaaactgtta ttgaagctat gaactatagt ttaagtgctg gaggtaaaag
    27961 attaagacca atacttacat tggaggcttg taaaatagtt ggaggaaatg aagatgaagc
    28021 tattcctttt gctattgcaa ttgaaatgat acatacatat tcactaatac atgatgattt
    28081 gccagctctt gacaatgatg atttaagaag aggaagacca acaaatcata aagtatatgg
    28141 agaagctatg gggattttag caggagatgc tttgttaaac tatgcttttg aagtaatgct
    28201 tgcaggctca atcaataaag aaaatccaga aaagtatcta aaagctataa atgaaattgc
    28261 caaaggtgct ggtatatatg gaatgatagg tggtcaagta gtagatgtag aaagcgaaaa
    28321 taaacaaatt gaaaaagaaa aattagatta tatacatatg aataaaactg ctgcaatgat
    28381 ggtaggctgt atgagagcag gagctactat aggtggagca aattctgaac aaatggaaga
    28441 aataactaaa tatgcaaaaa atatcggatt atcattccag atagtagatg atatactaga
    28501 catagtagga gatgaagcta agttaggtaa aaaggttgga agtgatatag aaaatcataa
    28561 gtcaacatac ccatctcttt taggtttaga taaatctaaa gaaattgcac ataatttgat
    28621 tgatgaagca aagaaaagta tagaaaaatt atctgatgat gtagattttt taaagggatt
    28681 ggctgaatat ataatagata gagaatacta aaatatacag ctaaaatcga ggagggaaaa
    28741 atggattttt tttcggagat ttttaacaat ggggctttgg gaataagtct gattgcttgt
    28801 ttcttagcac aatttataaa aatatttact ggtaaggaaa aaagaattga gttatcaaga
    28861 atacttattt caggaggtat gcctagttcc catagttctt ttgttacaag tttagctaca
    28921 gtggtaggta ttgaaaaagg gtttaattct actgattttg ctataattac cgtacttgcc
    28981 ttaattataa tgtatgatgc agcaggtgtt agacgagctg ttggtaaaca agctactata
    29041 ttaaatcaaa tggtggcaga tatacagcat ggaaagcata tagagcagaa gaaattaaaa
    29101 gaattaatag gtcatacacc actagaagtt tggtttggag ctttacttgg aatagtaaca
    29161 gctttaatat tgatgtaaat tgaaaattta cagaataaag gtgaggataa tatgtataaa
    29221 tatttagata aagtaaattc tccaaaggat ataaaaaata tgagtataga agaaatggat
    29281 ttacttgcaa aggatataag aaagttctta gtaaaatctg tttcaaagac aggaggacac
    29341 ttagcttcta atctaggagt ggttgagtta acattagcac ttcataaagt atttgatagc
    29401 cctaaagata agattgtatg ggatgtaggg catcaatctt atgttcataa aatagttact
    29461 ggaagaaaag attgttttgt atctttgaga cagtttaatg gactaagtgg ttttccaaag
    29521 gagaatgaaa gtcctcatga tatttttgat acaggacata gcagtacatc tatttctata
    29581 gctacaggta ttgcctgcgc tagggatata aaaaaagaaa actatagtgt tatatctgtg
    29641 ataggagatg gttctataac aggaggtatg gcacttgaag ctttaaatca attaggatat
    29701 atagatacca atatgatagt aatccttaat gataatgaga tgtccataga taaaaatgtt
    29761 ggaggaatgt ctaaatatct gtcaagtatt ataagaaact caacagttga gaaaatgaca
    29821 gatgaagttg ataaaatttt aaatgttaca caaacaggtg aaattttatc taagactgca
    29881 catagattta aagataaact aatgtatagc ttttctcctc aggactgttc attttttgat
    29941 tcattaggta taagatatta tggacctata gatggccata atactaaaga actaatagat
    30001 atattgagaa aagctaaaca caaaaaaggg cctgttcttt tacatgtaat tacgaaaaaa
    30061 ggaaaagggt acagatttgc agaagaacaa cctgataaat atcatggagt atcaaagttt
    30121 gatataaaga caggtgttac atctgcaaaa gttaagtcta tgtcaattag tgttggagaa
    30181 aaacttgttg atatggctaa taataatgaa gatatagtag caataacagc tgcaatgcca
    30241 tctggtacag ggttaaacct gtttgaaagt gcatatccaa aaagatatta tgatgttggt
    30301 atagctgaac aacatgccac aggatttgca gcaggtcttg caaaaaatgg tatgaaacct
    30361 tactttgctg tgtactcatc atttttgcaa agggcatatg accaagttat tcatgatgta
    30421 tgcataacaa aaaagccagt tacttttctt atagatagag ctggattagt tggaaatgat
    30481 ggagaaactc atcatggtat gtttgattta agttacttaa attctattcc aaatattgta
    30541 gtaatggctc caaaagacac aagagagatg gagcttatga tggatttgtc attaaaatta
    30601 gattgtccac tagcaattag atacccaaga ggaagtagtt attacctaga taagggagaa
    30661 tatggagaga ttgtactggg taaatatgag gtattagatg acggtcaaga tacagtcata
    30721 ctttgtattg gaagtatggt aaaacatgct ttagaggcta aagaaatatt atcaagagaa
    30781 ggaataaatc cgacaatagt taatgctaga ttcttaaagc caattgatga aggtatgtta
    30841 aaagcattat taaaaaatca taaaaatgta gttactatag aggataatat tgtaactgga
    30901 ggatttggaa gtagaataaa caagtttatt atagataatg aatataacgt aaatatactt
    30961 aatatagcaa taccagaaga atttgtaaaa catggcaata tagatgaatt atatgatttt
    31021 gtaggattat cgccaaaaag tattgctgat aaaataagga aattagttat tgagtaaaaa
    31081 tctaatgtag atattgtaaa ttaaaattta tataaaatat agaatttatc aattagaata
    31141 aatatcaagt gtgttacttc aagctacttt agttatcatt aaagtagctt ttaacagaaa
    31201 ggtaattgta tgaaaaaaag aatagattta ttattagtag aacaagggta ctttgaaagt
    31261 agagaaagag ccaaaaaagc aataatggct ggattggttt ttgttgataa tcaaaggtgt
    31321 gataaggctg gtacagaagt aaaagaagat tgtagtatag aagtaaaagg aaatccaata
    31381 ccatatgtca gtagaggtgg tttaaagctt gaaaaagcaa tgaaaaactt tgatttgact
    31441 attgatggaa aggtatgtat ggatataggg gcatccacag gtggttttac agattgtatg
    31501 ctcaaaaatg gagcaataaa agtattttct atagatgttg gttatggtca acttgcatgg
    31561 aaattgagac aagatgatag ggttgtgtgt atggaaagaa ctaatataag aaatgttaca
    31621 atagaatata caaagcagtt tgctgatttt gcgtcaattg atgtgtcttt tatatcgtta
    31681 aagttagtac ttccaaaggc aaaggagtta gtacgtcatg atggggaagt tgtcgcttta
    31741 attaaacctc aatttgaagc aggaagagaa aaagtaggta aaaaaggagt agttagagaa
    31801 aaatctacac atatagaagt tataaaaatg atttctgatt tctcagtcga aaatggattt
    31861 gagattttag ggttagattt ttctcctatt aaaggtcctg aaggtaatat agaatatcta
    31921 attcatttga gaaatggaaa tgaaggatat gaatttgatg gtgagacata caataacaaa
    31981 atagtagaag ttgttgaagc ttctcataat ttagacaaat aggttaaaag ggggcttaga
    32041 tttgatcctc gaattatata tgaaaaattg tgccttagtt gaagaactaa ggttgaatat
    32101 tgataaaaac ttaaatatac ttacaggtga aactggttca ggaaaatcta taataataga
    32161 tgcacttgga ctttgtttag gtgataaata tgataggtct tttttaagaa aaggaacaga
    32221 taagggactt gttgaggctg tatttttttc agacaataga tatcttaaaa aaatattaga
    32281 agaaaatgat ataagtatgg aagatgataa tttattggta ataactaggt tgatatactc
    32341 agatggtaag agtactgcta gagtaaatgg aaggactgtt aaagtgtctc ttcttaaaga
    32401 aattgcatct acacttatag atatacatgg tcaacatcaa aatcaagctt tgttcaataa
    32461 agatactcat ttaaaatttc tagacctttt tggagaaaat gaattggaag agtttaaaat
    32521 tgcttataaa aatgtgtacc ataagtatag tgaagtaaaa aaagctttaa attgcttgac
    32581 agaaaataaa gatgagatgc aaattcaacg agaaatagat ttattaagat ttcaaataaa
    32641 tgaaattgaa gctgcaaatc taaataagaa tgaatatgaa gatttattaa aacaaagaga
    32701 agtttataga aatagtgaaa agatatataa taatctaaat tcgagttata gcaagttaca
    32761 taatggtgag tataatgtta ttgacctaat aggtcttgca tctaaggaac ttaatgacat
    32821 atctaaatat gacagtgttt taagtgaata tagtgatact gtagaaagaa ttatgtatga
    32881 gttacaagac atatctggtg agataagaaa ttacaaagat aatatagact ttgaacctta
    32941 tgagctagag cagattgagc ttagaatcga cgaaattaat aatttaagaa gaaaatatgg
    33001 agacagtata gatgatatat ttgagtatta tggaaaaatt aaagatagat tagatgaaat
    33061 attaaataga gatgaaagag ttgaacagtt aaaaagcaaa ctgatgaata tagaagaaga
    33121 tttaaaaata aaagccagta aattgactaa agcaagaata gaagtagcaa ctactttaga
    33181 aaaaatactt cttgatgaat taaaaagctt aaatatgaaa aatgtaatgt tcaaggttaa
    33241 ttttgaaaaa ggttcattta ctttagatgg agtagatgat attgaattta tgatatcttt
    33301 taacttagga gaagatatta agcctatata taaagttgca tcaggtggtg agatgtccag
    33361 atttatgtta gcgtttaaaa ccatattggc tgatatagat gatattgata cattagtgtt
    33421 tgatgagata gatactggaa taagtgggat agcagcacag atagttggtg agaaattgag
    33481 tgatatagca aagaaaaaac agataatatg tataactcat ttacctcaaa ttgctgcaaa
    33541 tgcagacact cattattgta tagagaaaga tacttcaaat aataggacgt ttaccaatgt
    33601 tagtaagtta aatgaatctc aacgaaaaaa tgaaattgcc agacttatag caggtaacaa
    33661 tataacagaa aaaactattg aacatgcaag tgaaatcatt gaattggcta aaaaatgtta
    33721 gtgaaaaaca agcattttaa taggtgtaaa gaatttttat agaaatgctt tacacctatt
    33781 ttttatgatg aaattatttt aaaatatcta gtgcctatat tgaagaaaag taggtttgaa
    33841 aatggaatga actttgtata aatttgtaac tttgaaattt ctaaatgctt aagtataata
    33901 ttatttatta aggtagtagt gaggggaggc ataaaatgaa taaaaaagat actatgcact
    33961 taatttttat aattgtaatt tttattttat tatggtatat tgtggtagca gtaagtgaga
    34021 ttaataaaaa tattgaaagt tgtagtaaca aattagatta tttgtcacaa gagcttatga
    34081 gtactaagtc ggatattagt aatactataa atgaagaaat gtcaaaaagt tatataacaa
    34141 aaagtattga cttaaaagta aaaaaaatcg agaaaaaaga atgtactatt gatgtagatg
    34201 ttcaattaag taaacttgga aaaaatggaa aagtattttt tatgtataaa gaagatagtg
    34261 ataaatggaa tgaaactgag atgacaaaac atggggaatt atcatatgca tgtgaaataa
    34321 agataaatac aggaagtgaa tatgattata aagtagttac aagtggagat atatctgaaa
    34381 gttctgatgt acaaaaactg actaaatctg attatatgcc tgaacaacct atatttaatt
    34441 ctgggataag agataataga gaatacttta ttgaaatagt agaaaatagt aatcttttta
    34501 atcatgagag tgaaaagtca aaaaataaag cttacgataa tatcaggtta gaaaaagtag
    34561 atattattgt aaatgaagga aaaaaagaca ctatatacaa agcccaatta gctgaaggct
    34621 tagatgatgg caaaactaat aattcaaata gaaatcaagt gaattatgaa gtaagttttc
    34681 ctaaaaggga tattgatgac ataatttata ttaaagctaa acttacatac aataatggag
    34741 tagaatatac aaaggatata actgaagata taactatggg attacaagat ttagaaaaat
    34801 aaatacatat ttaaataaat attcaaatag atttgttcac aaatagagta taaataaaac
    34861 tgtagtagtt ttacttatac tctattaaaa aattataatt ttaattccat atatctagcc
    34921 ccttcaattg gattataagt ataaagttct atatcataaa aaccaaactt ttcatataat
    34981 ccttgtgcac ttttcatgct tggaagagta tctaatctca tgtgtgtata tccaattttt
    35041 ttagcttcta caatgatttc ttccaatagt atttttccta tttttaatcc tctaaattga
    35101 tttcttacat ataatctttt taattcacat attttacctt caagtttttt taaagcaaca
    35161 caacctgcca aattttcatc aacaaatgcc aatatcaatg agcctgaagg ttttttatat
    35221 tttcctggaa gtgtttttaa ttcattatta aagtcttgaa aacataagtc tatatttaga
    35281 gaatttgaat attcagtaaa tagaagtttt acgttttcaa gattttctaa atctttttct
    35341 tcaacaaatt gtaaagttat attttgagcc attttatccg ccattatata aacatgttta
    35401 tataatgact tcacctcctt gatatatgta tatttttctt aatatcaatt agattttaat
    35461 accattactt tttcaccacc atagtcaagc tctccattaa acttaaatcc aaaatcttta
    35521 taaagcttaa tagccatttt attgtcttcg aatatactaa gatatagttc atcacagtta
    35581 tattcatttt taagatgatt tacaagaaaa tctaatgatg cttttccaca tcctttacct
    35641 tgatattttg aatcaatcat aaatctatca agccaaactc tatcatcttc taaacgacca
    35701 tacatagcaa atcctattaa agaattttca tcatatattc caacaggtac ccaagctgtt
    35761 ataaatttag attcagcaat agaaagtgca ttgctttcta tgtaatctaa ctgactttta
    35821 tctacagaca aactaactaa atcgtgccaa ttatttatgt ctgcaattct tacatttaat
    35881 ttcaagatat taccgtcctt caaacttttt gttacaatct aatactatca tattatgtat
    35941 taaaaatcac ttattaagat tttaaataaa ctttttgaat gaataaattc tcaggaaaaa
    36001 ggaattataa atacataata atacagcata ggagtagatg gatatatgaa caaaataaat
    36061 aaaaatttca aaaatatttg gataatatta ggagctgtat cgatttttac catggttata
    36121 atttttaata aaaattgtaa tgttaataaa gagactcaaa tagaagcttt tacaattaag
    36181 aatcatgata aaaaatttgt atatcctatg ggaaatataa ttggagtaaa agcaaataca
    36241 gatggtgtat tggtcttagg atatgaggaa gaggatgtag gctatattgg aggcatacaa
    36301 ataggtgata atatagtaaa aatagataat aaaaggataa aaaatagtca agatgtatca
    36361 gagattttga ataagattaa aaaaagtaaa gttgaagtga cttttgagag aaaaaataag
    36421 tataaaacag aagtaataga gactaaaaaa gaaaatggca agtataaact tggattatgg
    36481 gtaagagata aaatatctgg aattggaact atgacttttt acgaccctag tatggaaaag
    36541 ttcaaagcaa tcggtcatgc cataaaagat tcggatacta atgaactatt aaagataaag
    36601 caaggctata tatataagcc agaacaatta aaaatagtaa aagctagtaa tgaaaaagta
    36661 ggtaaaataa aaggagattt taatgacagc aatttaatgg gtaatttctc aaataattca
    36721 gagctaggta taagtggtaa tattacagaa aaccataata aagagtttaa tgtagcaaat
    36781 aaagaaaagc aattaataga agttggaaga ccgcaagatg taaaaatagg agatgcagta
    36841 attctttttg aggataaaaa caaaaatata acaagctatg atataaaaat agaaagtata
    36901 gtatatgata aaggaaatta tagagatatg gtaataaaag tagtagatga caagttattg
    36961 gaatacacag gaggtatcgt acaggggatg agtggagctc caataataca aaataataaa
    37021 attattggtg caataactca tgtttttaga gataatccga aaaaaggata tggtattttt
    37081 atagatgaaa tgataaaatt gtaggtgagg cattaaaaaa ttttattatt ttatcaatta
    37141 tctaggagga atataatttt ggagtgtcga atatgcttta gagtagataa ttaggaagca
    37201 attgtgtaaa aagtttagtt ttctgtaata agaagatgtt ttttaatggg gggattttta
    37261 gtggaaaaaa tcaaaatagt tttagcagat gacaataagg atttttgtca ggtattaaaa
    37321 gagtatttgt ctaatgaaga tgatatcgat atattaggca tagctaagga tggaattgaa
    37381 gcattagact tagtaaaaaa gacacaaccg gacttattaa tactagatgt aataatgcca
    37441 catctagatg gattaggtgt aattgaaaaa ttgaatacta tggatatacc taaaatgcca
    37501 aaaataatag tactatcagc agtaggtcaa gataagataa ctcaaagcgc aataaatcta
    37561 ggagcagatt actacatagt aaagccattt gattttgttg tgtttataaa cagaattaga
    37621 gagctagttt ctaatagagt tacacaagtt gagccaaaac ctagaccagt tcaagagact
    37681 caaatgacta gaagtgattt tgttaagaat gtaggaaata tagagacaga aatcacaaat
    37741 ataatacatg aaataggagt accagctcat ataaaaggat atttatattt aagagaagca
    37801 ataaaaatgg ttattgataa tgttgagctt ttaggtgcag taacaaaaga gttatatcca
    37861 agtatagcta aaaaattcaa tacaacacca agtagagttg aaagagcaat aagacatgca
    37921 atagaggttg catggagtag aggaaaagtt gacacaataa atcaattatt tggatatacg
    37981 gtacacaata ctaaaggaaa accaactaat tcagaattta tagcaatgat tgctgataaa
    38041 ttaagactag aacatagtat ggttaaataa acaagacata aaaagtaagg ctttttaatt
    38101 aaggcattgg ctataaatgc gtattacaag cagcgaaacg gtataaccac tagggttata
    38161 ccgtttcgct attttaataa atataaaaat tttctttatt atttgcttac tatatcaata
    38221 taataatttt attatactat ggatatagta tgtgtcttta caagttgtaa actgacagtg
    38281 gtttattttt taatataaat attgactttg atgcaggtaa actttgtatt tttaagcgta
    38341 ttatggaata tgttaaataa aaaaatgatg aaatatagta ttgtaaatgc caaagatgca
    38401 aaacaaactt aaaacattta ttttattgtt aagtaatgct ataatataat gtgattttaa
    38461 taatgatagt ggaggtttaa atatgagagt cgaggcccct ataaaagtag atcgaaaaac
    38521 caaaaaactt gctaaaagag ttgaaagtgg ggaaatagca gttataaatc atatagacat
    38581 agatgaagtt gctgcaaact ctttagtaga agctaaaata aaacttgtca taaatgcggc
    38641 tccttctata agtggtaggt atcccaataa aggtccaggg atattaactg aaaataatat
    38701 actaataatt gataatgttg gagaagagtt atttgaagaa ttaaaagaag gagaaactat
    38761 agaagttgta gatggaaaga tatatagaaa aggaaaattt ttaggtgcag gagaagtttt
    38821 agacaagtat gaggtttcac accaaataaa ggctgcctat gagaatttag ctgtagaatt
    38881 ggatagattt atagataata ctatagatta tgctaaaaaa gaaaaaggat ttatacttgg
    38941 agaagtagaa attccaaaag tgaaaactaa ttatgctaat aaacatgtat tgatagttgt
    39001 aagaggtcag gactacaaag aagatttaag tactatgctt tcttatatag aagaggtaaa
    39061 gccagtattg gttggtgttg atggaggagc agacgcttta attgagtttg gatatactcc
    39121 agatgtgatt gtaggtgata tggatagtgt aagtgatgaa gctttaaaaa aggctagtga
    39181 aatagtagta catgcttata cagatggaag agcaccaggt cttaagaggg ttgaggaatt
    39241 aggcttagat gcagttgtat ttcctgcgcc aggaactagt gaagatatag ctatgcttat
    39301 cgcctatgag tataaggctg agttaatagt agcagttggt acacattcaa atatgattga
    39361 ttttcttgaa aaaggaagaa aaggtatggc aagtactttt ttagttagac taaaaatagg
    39421 ttcaaagctt atagatgcta aaggcgttaa tttgttatac agaagtaaat taaaaataaa
    39481 gtacatatgg gcattaatag caacagcatt atttcctgtg ttggtagttg catcattgtc
    39541 accaggagtt caacagttca tacaactaat gcaattaaag tttagagtat tattacagat
    39601 gtaaatttta ggaggataaa tatgcatatt aatatgaaat attatatagt cactataggg
    39661 gctatattta tagctttggg tataggcatg ttagtaggat ttaatttaaa taataatcaa
    39721 caattaagtg aacaacaagc aaacataata aatgatttgg atgataagtt taatatctta
    39781 aaagaaaaaa atgataaact tgacagtgac ttagcaagtg taaatagaga ttatgaagag
    39841 gcagttaatt ttataaataa aaatgtagat aagattttag ctggttcgct gaatggtaaa
    39901 agtataggaa taatatcggc taatgaaaat gacgattata caaaaaatat agaagacata
    39961 ataaataaat ctaatggaag tattgcattt aatatagtat taaaagaaaa tataacaaat
    40021 ccagaaaagt taaaggaaat gtcaactaaa ctaggtacag atgtaaaaaa tgcaaatgat
    40081 gcagttaatt atataattga cacccttaaa aaggaagatg caagtgacat tttaacatat
    40141 cttcaagaac tagatgtaat aaagtttaac tctcttggaa atacatatct aaaatatgat
    40201 tctgttgtaa tagctggtgg aaatgatgca aaagacagta caaaacagtt tgaaaaaata
    40261 gaaaaatttg tagtttcaaa acttaaatca gagaataaat atttagtaga agttcaaaat
    40321 acaggagtta aaacttctta tgtagaacta tattctaaaa acaaagttgc aactatagac
    40381 aatattgatg aaggtatagg aagtatatct ctagctattc ttctacaaca aggtaatata
    40441 gttggtaatt ttggtagatt ggatactgca acttcattgt tgccatctat taaatagaaa
    40501 taattttaag gagagaaaaa atggattctt atataagtat aataatacca gcttataatg
    40561 aagaaagtag aataaaatat acattagaaa gcatattgga cattaagcaa ataaatgaaa
    40621 taatagttgt ggatgatggt tcaattgaca atactgctaa ggttgtatct gagctagaaa
    40681 atgaaaagat taaatttttt aagttagata aaaatagagg taaaggatat gctttaaatt
    40741 atggtatcaa attagcaatg aaaaatgcag atattatagg ttttctggat ggagatttag
    40801 gaagctctgc taaagaagtt gaaaaattaa tagtacctat attaaatggt gaggcggatg
    40861 ttacaatagc caagtttcct cctgcaaaga gaaaaggagg tttgggattt gtaaaaggtt
    40921 tagctaaaaa ttctgtgttt gagatgactg gtgttgagtt agatgcaact ttatcaggtc
    40981 aaagaatatt taaaagagaa gttttagaaa agtttgatga aatacctttt ggatatggag
    41041 tagaagttgg aatgaccatt gatatattaa agtatggatt taaaattaaa gaagtattag
    41101 taaatatgac tcataatgaa acaggaagaa atttaaaagg ttttattcat agagggaaac
    41161 agtattatca cataaaaaag gttttaggac aaaaaaagaa agaatggagg taatatctta
    41221 gtgaaagatt atatacttta taccatttta ttattaactg gattatttgg aacctatgct
    41281 gtaattccac tatttaaaaa tttattgata aatggaaatg tacttagacc aaactataaa
    41341 aaagatatga taccagtaag tatgggaatt gtatttttgc ctatgattgt aatcaatgga
    41401 ataatacttg ctttctttac tacagaattt aaggatttag cgtatatatt tatgtttatg
    41461 tttggtatga tatccatgtt ttttgcaggg atactagatg atgtcattgg aaatagagat
    41521 gtaagtggtt taaaggggca ttttaaaagt ttatttaaag gaagtcttac aacaggaggt
    41581 tttaaagctt tatttggtgg atttgtaggg cttatagttt ctgttgctat atcaaaagac
    41641 ataattgata taatagtaaa tacactaata atagctctat caactaattt aatgaatctt
    41701 ttggatttaa gaccaggaag ggcaataaaa gcatatttat tcataatggt aattatattt
    41761 ttaacattga caggatttgt tcaagttctt ccattactta tagtaccaaa tgtacttgca
    41821 tactttaatt atgatttaaa agcaagggct atgatgggag atactggttc aaacgtcctt
    41881 ggaatatcta ttggaatgct catttctttt gggtatccat ttaacattag attaggatgg
    41941 ttaatatttg tagttattat gcatatattc actgagaaat actcattaac taagataata
    42001 gaaaaaaata aactattaaa ttttatagat aaattgggaa ggtagtatta tgataagcaa
    42061 aagagtgggg attgttgaat caatagtaag tcaaactgaa actctagatg atataagagt
    42121 aaatataaat ggaaaaatac aaagggcata taattatccc aaaatatctg gaactataaa
    42181 tataggtgat gaagtggttt taaatacaac agcagtagaa ctgagcttag gtacaggtgg
    42241 ataccatttt gtaataacta atttaaataa tatagaatct actttaactg aaggtgggca
    42301 tataatgaaa cttagatata cacctcttca aataaaagtg gattctgttg aggaacaaga
    42361 aagtatttat catgataaat ttgcgaattt taaaggatta gaaggtcttt ctgttgtagt
    42421 agggactctt catagtatgt taactccatt tgcagcttca tttaaaagaa ataatccaaa
    42481 taaaaaatta gtatatataa tgactgatgg agcatctctt ccaatttatt taagtaaaaa
    42541 tgtggacact ttaaaagaaa aaaaattaat agatagtacg ataactatag gaaatgcgtt
    42601 tggtggagat tatgaatgta taaatatata tactgcatta attacagcaa aagaaatact
    42661 aaaagcggat gcagtatttg tcagtatggg acctggaatt gctgggacag gaacaaaata
    42721 tggatttaca gggattgaac aaggctctat tcttgatgcc gtaaaaaaac ttgaaggaag
    42781 agcaattgca attccaagaa ttagttttgc tgacaaacga gaaagacatc aaggtatttc
    42841 acatcatagt atgactgtat ttaaagaaat tgtaaatgta aatgtagaca taccaataac
    42901 tatatatgat gatgaaaaat tgaactttat aaaagagcaa atcaatttaa atggtttaga
    42961 caaaaagcat aatataattt atatagataa taataaaacg aaagaggatt tagactattt
    43021 taatctaaaa gtaaagagta tgggaagaaa ttatgaacaa gatgaggcat ttttcaaagc
    43081 tgcaagcaca gcagcatatt acttaatgga ggtttaagat ggtattagaa gaaaaaacta
    43141 ttagtagtga tagggtttat acaggtaaag taattacttt aaaggttgat actgttgaaa
    43201 ttccagggca aggatatcaa aaaagggagt tagtagaagt tggtggagca gtaggaatag
    43261 ttgcaatcac agatgataat aaagttgtac tagttaagca atttagaaaa cctatagaaa
    43321 agccaatctt tgaaattcca gctggtaaac tagaaaaaaa tgaaagtcca aaagaatgtg
    43381 ctgaaagaga attaaaagaa gaaactgggt atagtgcaaa aaatattaag ctaatacata
    43441 aatttttcac ttcagcaggt ttttctaatg agataatgtt tgtatattta gcaacaggtc
    43501 ttactccagg agagaataat ttagatgcag atgagttttt agatgtctat gaaattgagc
    43561 ttgaagaagc atataacatg gtattaaaaa atgacgttga agatgcaaaa acatctattg
    43621 gattattatt agtaaaagat atgtttaaaa attaatattt ataaaatgaa taaccctttg
    43681 tcctaaagca tattatttta taaaggacaa gggggaatta aattgagaag aacatataga
    43741 aaaaatgatt ttagagaatt aaatagacaa ataattatta taggattgtt gtttatgatg
    43801 tctattgttg ttgggtctta cataaataaa atattgccag gttctagtaa caatatatta
    43861 aacaatataa atcctgctgt agagtattat aatctaaata taagcataaa agatacagtg
    43921 atacaaaatt taaaatcaga tgcaatcttt atgggctcaa tagctctatt aagtctattt
    43981 gtagtaacaa ttccagcagt gttggtagct tttgtattaa aagggatgtc aattggttat
    44041 acaataaata gttgtatatt ggcattaaaa tttaaaagta taaaaatgat tttaataata
    44101 ttatttaaaa atttgattat tattccatgt gcaatcatat tagcattaat tagtttaagt
    44161 tattttaaag aaatggttta tgaatttaaa aagaaaaata gaaaaaatat gcaattttta
    44221 attaagaggt atatactaaa tattataatt ataatagcac tatcattggg gttgcaatta
    44281 atattaaata ctgtaagtat tggtattatt aagttcctag ctaaataaag gagtttataa
    44341 tggatattat agagggatat atagattaca taaaagataa aaaaaaatta tcagagaaca
    44401 cagtggcatc atactttatg gatataaaaa aatatatgga atatataaat caaaaaagca
    44461 ttaaactagt agatatagta gaaaatgata ttataagtta cttaataaag ttggaaaaag
    44521 ataatgtatc aatagctaca atagcgagga tgatatcctc tataaaatct tttcatgatt
    44581 atttattttt aaatcatata tgtacaaata atcctgcaaa ggatataaaa aaacctaaaa
    44641 taaaaaaaga aaatataaat atacttacag aagaagaaat tgaaagacta ttaaattttc
    44701 caaagttaac aacacctaaa ttgattaggg acaaggctat ttttgaagta ttatatggta
    44761 ctggtataaa agtatctgaa ttagtagaga tgaatataga ggatattgac ctagatattg
    44821 attatatata ttgtaattca tgttgtaaaa atcaaagagt gataccactt tgtgatatta
    44881 caaaacttta cttagaaaag tatctaaaag aagcaagacc taaaatggct gtagaaggtg
    44941 aaaaatcatt attcgtaagt tcattaggtc aaaggtttac acgacaaggt ctttggaaag
    45001 tcataaaaaa atattctaat ctagccaata tagataaaaa tataaatcct acaatgctta
    45061 gacattcatt tgctattcat ttgttaaatg aaggtgctaa cattgctgtt gtaagtaaaa
    45121 ttttaggaaa tgttaattta tctagtttgc aagtatattt aaatcatata gataaaaacg
    45181 tgagaagaga aataaaggaa aaacatccta gaaatgatgt tgatgtagaa ttacaaaaag
    45241 cagaagctaa atagactata tagcaaattt tataatttaa aaggagtata tttatatgag
    45301 cagagtaatt tggattgtaa ttgatagtgt tgggatagga gcattacctg atgctgaaaa
    45361 atttggtgat agtaaggatg taagtaccct tggaaatata tttaaggaat atccagatat
    45421 tcagattcct aatatgagaa atttaggtat aggaaacata gatggtatag atttttttga
    45481 aagtataaaa gaaccaatag gttgttttgg aaagtgtaag gaaatgtctc agggaaaaga
    45541 tactactaca ggtcattggg aaatgactgg tataatagtt gacaaaccat ttaagacatt
    45601 tgaacatgga ttctctaagg agataataga agagtttgag aaaaaaactg gaagaaaagt
    45661 agtaggaaat aaaccagctt caggaactgt aataatagat gagtatggag agcatcaaat
    45721 aaaaactgga gatgtaatag tatatacatc agctgatagt gtatttcaga ttgctgctaa
    45781 tgaagaagta attcccctag aagaactcta taatatgtgc aaaatcgcta gggaaataat
    45841 gatgggggat aatgcagtag ctagagtaat tgctagacca ttcataggta agaaaaaagg
    45901 tgagtttgtg aggacttcaa atagaagaga ttattcacta gacccatttg aaccaacagt
    45961 tcttgataat ataaaagaat caggacttga tgttttagca gttggaaaaa tagaagatat
    46021 ttttaatgga aaaggaatta cagatgctat ccacactaaa agcaatatgg atggagtgga
    46081 tgaaacttta aattatatga aacaagataa taaaggtcta atatattcaa atctcgttga
    46141 ttttgattct aaatatggtc atagaagaga cccagaagga tataagaaag ctcttgaaga
    46201 gtttgatagt agacttcctg aaataatggc taatatgaga gaagatgata ttttaataat
    46261 caatgcagac catggaaatg acccaacata taaaggtaca gaccatacaa gagaatatat
    46321 acctgttatg atttatggca ataagattaa aaaaggtttt aatttaggag taaaagatac
    46381 ttttgctgat attggagcaa ctgttgcaga tatactaaat gtaaagttgc ctaaacatgg
    46441 gtcaagcttt aaagaagatt tattttaaac tataaaatga taaaaactta gcttaatagg
    46501 atggagagat tggaatgttt gaaaagatag cacaaagtag taaatttata aattctaaaa
    46561 gtaatataaa acctaagatt ggtttgatat taggttctgg actaggtgat ttagcaaatg
    46621 atatagaaga ccctgtcaca attaaatata gtgaaattcc aaacttccct gtatcaacag
    46681 tagcaggaca tgctggacaa cttgtaattg gaaaacttga aggaaaagaa gttattgcta
    46741 tgcaaggtag atttcattac tatgaaggat attctcagaa agaagctact tttccagtaa
    46801 gggttatgaa agaattagga gtcgagattc ttatagtaac taacgctgct ggaggcgtaa
    46861 ataaagaatt taaagcagga gatttgatgc ttataagaga ccatataaac tttagtggaa
    46921 gtaatccatt agtaggaaaa aatgatgaca gatttggtgc tagatttcca gatatgtcag
    46981 atgcatattc ttctaaatat gtagatgtag ttaaaaactg cgctaaagaa tgtaatatag
    47041 atgtcaaaga aggcgtttat atgtttttta gtggtccaaa ctatgaaaca ccagcagaag
    47101 tgagaatggc acaaattttg ggagctgatg ctgtaggtat gtctactgtt ccagaagtca
    47161 tagtagcttc tcactccaat ataggagtta ttggtatatc ttgtataaca aatatggctg
    47221 ctggcatctt aaatcaacca ctaagtcatg aggaagtaat agaaactact caaaaagtta
    47281 aatcagaatt tatgaattta gttaaaacaa cggttaaaaa tttataagtt aaagcttatt
    47341 atatattttt tgaggaagtt tataataaaa tagttaatgt ttaatttgaa aagaattaat
    47401 aaaaagctgt cttgatatag aaagttattt ctaataaagg acagtttttt tataatacta
    47461 caacatttga aagtgtttta aagtttaata tttatttaaa ttattataga ttagaatgga
    47521 gatttcaatt atgagaatgt atgatattat aaaaaaaaag agagataact tagagcttag
    47581 taaaaaagag ataaactact ttatagaaaa ctattcaaag ggagatatac ctgactatca
    47641 agcttctgca ctattaatgt cgatttattt aaataagatg aataaacagg aaactgtaca
    47701 tcttacagaa gcaatgatga actctggaga catgataaac ctgtctgagg tagatggaat
    47761 aaaggtagat aagcatagta ctggtggtgt tggagataag actaccatag ctcttatacc
    47821 tttggttgct tcatgtggag caccagttgc aaagatgtca ggtagaggtc ttggtcatac
    47881 tggtggtact attgataaat tggagtctat accaggtttt tcgacagaaa tggagataag
    47941 taaatttatt gattctgtaa ataagtctaa aatagcagtt tgtggtcaaa gtgcaaaggt
    48001 agcaattgca gataagaaaa tatatgctct tagagatgtt acagcaactg ttgataatat
    48061 atcattgata tcatcaagtg taatgtctaa aaagttagct tcaggagctg atgcaattgt
    48121 gttagatgta aaaactggtg atggagcatt tatgaagaca ttagaagagt cttttgagtt
    48181 agctaaatct atggttgata taggtactgg tatgaataga gatacaatag ggattgtaac
    48241 agatatggat gaacctttag gttttgcagt gggaaactct ttagaagtta tagaagcaat
    48301 tgagacatta aaaggaaatg gccctaaaga ccttgttgag ctatgtgaag tattaggagc
    48361 atatatgttg gttttatcaa aggtagcaca tgattttgaa gatggtgttg aaaagataag
    48421 agaatcaata aaatctggta ctgctataca aaaactcaaa gagtttatag agaatcaagg
    48481 tggtaataaa gatgtagtag atgattattc tttattcaaa aaatcaaagt ataaatatcc
    48541 agttaaatca attaaatcag gttatataag taaaattaaa gctgaagatg ttggtgtatc
    48601 agctatgatt cttggagcag gtagagaaac taaagatgat attttagatt tatcagcagg
    48661 gataatttta gaaaagaaag taggagatta tgtaaatgaa ggtgaagttt tagcttacat
    48721 gtattataat gatgaacaaa agctttcatt ggcaaaggga agatttattg attcctactc
    48781 tattgtagat tcaaaaatag aaaaaaataa attaatatat ggtattgtaa ctaaagaaga
    48841 gattaaaaag ttttagaaaa ttttagaaaa gtgattataa aaggcctaac atgtcaaaaa
    48901 taatgttagg ttttttattt tttgataaac tataaattat accaaaaata tatattttaa
    48961 aacatttttt acaatataaa taagtttatt ctacaagatg attgaaaatt aaagtatcta
    49021 gttttataat agaaaatgga taaatataca taaggagtag attatattat gaactttaaa
    49081 gaaaatagat tgaaaatagc agtattaata attgttattt tgattatctt agcaggtata
    49141 tttgtgttta tacaaatagg tccttatgat aaaaataaca aaaaagatgt aattattgac
    49201 gttccaagtg gagcatctgt tggaaaaata tctgacatat tatatgaaaa taaattaata
    49261 aagaatgaac tattatttaa acttttggta aaggttagca ataaagctcc gtctataaaa
    49321 tcaggaacat acttacttaa tcaatcgtat tcaaacaatg atataataag tcttttagtt
    49381 tcaggtaaaa tatatcagga tggtataaaa gtgactattc cagagggagc tacatctaaa
    49441 gaaattatag caatgttagt aagtaaaaat ttaggagata aagctacttt tgaaaattta
    49501 ataaaaaaac ctcaagaatt ttatgataaa tttccatatt tgaaggaaga tggaataacc
    49561 tctttagaag ggttcttgta tccagaaact tattatttta attcaaagaa acaatcagaa
    49621 gaagatattt taagcgaaat gttaaaagta tttgacagta aatacacgga caagtttaaa
    49681 aagaaacaaa aagaattaaa tatgactctt caagaagtaa tggaaatggc atcaataatt
    49741 gagaaagaag ctgttcttga caaagacaga cctataatag caagtgtgtt ttataataga
    49801 cttaaggtag gtatgcctct tcaatcagat gctacaatac aatatatatt tgaagagaga
    49861 aagaaaattg taacatatga tgatttaaaa attgattcac catataatag ttataaaaat
    49921 aagggattac ctcctacacc aatatcaaat cctggtataa aatctattga agcagcatta
    49981 tatccagaga aaacagacta tttatatttt gtagctaaga ttgatggtgg aaataattat
    50041 agtacaaact atcaagacca tttaaaatac gttaaagaat ataaagaagc aagggataaa
    50101 caatcaaaag atacaaaagc aacaaataaa gaaaatacaa aaaaataaac catgattata
    50161 aaaagtctaa cagggtaaga ataatgttgg gcttttttat tgaaaattgt tattcttaga
    50221 tttataataa agaaagtgta aatatatata acaatatgaa tttaaaaaat aataaattaa
    50281 tataaaactt gaatatttat tattttaggg agtgttttta tgagtaatat agttaatgat
    50341 ttggttgaag attatataag agtgacatta aaagaaaaag aaggattttt aaaagattta
    50401 gaaatttatg cagaggaaaa tagtgttcct ataatacata aagaagtttc agatttatta
    50461 aaagtcttgt taaaggttca aaaaccaaag agaattttag aagtaggatg tgcaattggt
    50521 tattcttcta ttttttttgc aagtattata ggaaaagatg cagatataat aactgttgag
    50581 agaaatgaaa aaatgataga aaaagcaaaa gaaaacataa aattagctgg atttgacaat
    50641 aacataacta tactagaagg agatgcagaa gaaaaactta gtcaagtcca aggtgaattt
    50701 gaccttatat ttatagatgc agccaaaggt caatataagc tattttttga tttagttata
    50761 gataaattaa aagatggggg acttttagta tctgataata ttttgtataa aggtatggtt
    50821 gctcatgatg attttgttgt aagaagaaaa aagactatag ttaaaagaat gagaaattat
    50881 ttagattata tatgtaattg tgactattta agcacatcat tggtaccaat aggtgatggt
    50941 gtagcactaa gttataaaga aagtaaaaga ggtgatgtag atggaattaa ataaagtaga
    51001 acttttagct ccagcaggtg atttggagag attgaaaata gctataacat atggagcaga
    51061 tgccgtttat ataggtggag aaatttttgg aatgaggtct gcagcgaaga attttagtaa
    51121 ggaagatatg gcagagggag tagcttttgc acatgaaaga ggcaagaaag tattcgtaac
    51181 agtaaatata atacctcata atgaagattt tctacaatta gaagactatt tgttggaact
    51241 agaagagata ggaatagatg cagttataat agctgaccca ggagtgctta gtgtcattaa
    51301 aaaagtaatt ccgaatatgg aaatacattt aagtacacaa gcaaatacaa ccaattatct
    51361 aagtgcaaac ttctggtacg agcatggaat aaaaagagtt gtagtggcaa gagaattatc
    51421 ttttgatgaa atatctgaga taagagcaaa aacaccttta gatatggata tagaagcgtt
    51481 tatgcatggt gctatgtgta tttcttattc tggtagatgt ttaataagca actatatgac
    51541 tggaagagat gcaaacaaag gttcttgtgc tcaatcttgt agatggcaat atcatttggt
    51601 ggaagaaaaa agacctggtg agtattttcc aatatacgaa gatgaaaggg gtacattctt
    51661 ctttaactca aaagatttat gtatgataga gtatatacca gagttaatca aatctggtat
    51721 aacaagttta aaaatagaag gtagaatgaa gactgcatac tatgtagcta ctgttgtaag
    51781 agcatacaga atggcaatag atgaatttta cagagcccca gaaaactgga agttcaatcc
    51841 aatgtggatg gaagaactaa aaaaaggtag tcatagacat tttacatcag gtttttactt
    51901 gaataaacca acaacagaag accaaaatta tcaatcagca tcatatgtta gaaactatga
    51961 ttttataggt atagttagag aaacagaaga tgaagatggt cttattgttg ttgagcaaag
    52021 aaataaaatg tgtgttggtg atgaaataga agttatggga ccatataaag aaactatgtt
    52081 tactaaaatt gaagaaatgt acaatgaaga aggagaagct atagaatcag ctcctcatcc
    52141 tagacaaata gtgaagttaa agctatcagt aaaagttggt aaagattata tgcttagaaa
    52201 agttatagaa gaaaaggttg aagaataata aaaaattgat aaaaatagta ttagcccctt
    52261 agaaattgtc aataatgaaa ttatctaagg ggtgatttca tgtcaaaaaa gaagactcca
    52321 tttttgaaaa aagtgggaaa gagaagctgg tgtatattta ctataatttt aataatttat
    52381 agtgttttaa tttataggct agttgatata caagtattaa aaggtgataa atacaaacaa
    52441 agtgttgaat cacaaagcgt tgagaaagtc gagttaaata gtggaagagg aataatctat
    52501 gatagaaaca acaagaagct tacagataca agtaaatctc aggtattaat tgttgaaaaa
    52561 gaaaaattaa ataataacta taaaattttg gaacttatta agaaagctac taagatgaat
    52621 gatttagata tatataaagc tgtacaagag caattgacac gccctataat acagattcag
    52681 actaaaaata tcgataagag tatgaaaaaa gaacttgaga aaaatggaat aatggtagaa
    52741 gaaaaaacta tgaggtacgc aaaagatggt ttattatcac atacaatagg atatataaaa
    52801 gaagatgata aatcaggtca atcaggaatt gaaaagagta tggatagtgt acttagaaat
    52861 tcaaatgaaa agtatataag tgcttttaaa gctggagatg caggaaatga aaaatctcta
    52921 aacatactaa agggaagtgt aaaaactgtt gataataagg ataaagatag acatctaaaa
    52981 actactattg attataacat tcaaaaaaaa ttagaacaaa tactaaataa agaagaaaat
    53041 cctacagcag caataatctc ggaagcatct acaggtgaaa ttcttgcaat gtgctctaga
    53101 cctaattttg accaaaatga catatcaaaa agtttaaaag gaaaaaatgg ggaatttgaa
    53161 aatagagtta taaaagcgac atatccacca gggtctgtat ttaagatggt agttttattt
    53221 tctgcacttg aaaatggtgt tatagatgag aactatactt acaactgtac aggtaagact
    53281 aaagttggga atactaatga aatactgcga tgtaataaaa gagatggtca tggtttccaa
    53341 aacttaagac aagctttttc taattcatgc aatcctgcat ttttagatat agctatgaaa
    53401 cttggaaaag aaaagatact caaatctgct gaaaaattac atttatttga aaaggttgat
    53461 attggtcttg atgaagaaaa aattagagaa gctccaaaaa acatatcaat aagaaattta
    53521 gctataggtc aagaaaatat agaatttaca ccacttcaaa taaatcaaat gactcaaata
    53581 atagctaata atggaacatt caaaccacta tacttatata aaagtcttgt ggacaataat
    53641 atgaatacaa taaaaactta taagtcttca aaaaaagaag aacttatttc tccttatgtg
    53701 tgtacacaag ttaaagaata tatgaagtct gtatctagga ttggtacagc taaagaccta
    53761 aaagatattg aaggtggttg tggagttaaa actggtacag ctcaaagtag tttaaataaa
    53821 aaagctatag accacggatg gataacagga ttttatcctg aagaaagacc taagtatgta
    53881 ataactgtgt tagtagaagg aactcaaaaa ggaaataaat ctgcaacacc tatatttaag
    53941 gaaatatgtg aaagtataaa ataaattatg tactataaaa tttaaggata tatcgtaact
    54001 ttgattttag atagaaaact ttgtctaatg atgtacgata tatcctttta aaatatagta
    54061 ttaactttct tgaacaagct ctttttctag ttttttaaga gctttttttt cgattctaga
    54121 tacatatgac cttgatatat cgagtttttg tgcaatttct ctttgtgtct tatagccata
    54181 aggagttaac ccatatctta actggacaat ttctctttct ctaggagtaa gaattttgtt
    54241 tagttgttcg taaagttttc caacttgaac ttttagttca acttcatcaa gaacatagtt
    54301 agcctctgtg ccaagtatat ctaaaagact tatttcatta cacactactc tttatatgtt
    54361 attggtatta ctggtcttca tgtaatttca aatgaaccat taattcaaaa gaatctagtt
    54421 tttgttcttt agacttataa taaattgctt tatcaattac agattttagg agtttatttt
    54481 ttccaaggga atctgaatca tgataaagtg ataacacagt tttaatatct tctattattt
    54541 tagaattgtc ttttttaaca gtactcaatc tattttttac tgtcttaatt gaatctttaa
    54601 tttcttcagt tcttgaactt atattgttgg acctttcaat aaatgtatct tcatcatata
    54661 ttccacgttc taataaatca tataacttat ttttttgttt acctaattct tttaattcag
    54721 tttctaagcc ctttaagact cgtttttgaa attctatatt actatcttta ttatttttat
    54781 ctaagtctaa atcacatgct tttaattgat atttttttac cgtgtcttcc aaagatttta
    54841 aaatggcagc ttcaataaat tcaaatcgag aacttttatt gcaaccagga tggtaacaaa
    54901 ttatatagtc gtggtctgca tatggtctat atactaatgg tctaccacaa tttttgcaaa
    54961 tcactattcc tgcaagtgga ttttttattt gattaccata gctgacatga ccgttttttt
    55021 taagtatatt ttgagctttt ttccatgtta tttcacttat taaaggttca tgctttcctt
    55081 ttgcttcaat ccattcatct ttaggtctta gcttaacagt ttttatttta tttggatttt
    55141 tagatttttt atagtccttt ttttgccact gaatgtagcc acaatatacc ttatttttta
    55201 ttatatttgt aattgcagaa ttgtaccaat tagcacctgt agcagtttta atgcctaagt
    55261 tatttaggta ttttgatatt ttactacaac ccatatcttc attaatatat aagtcaaaga
    55321 tagtcctaac tacatcagca tccttatttg gtacaagtat tctttctttt ctacctgttg
    55381 ttacagcatc atatccaaat ggagcagaag ttcctatgaa attcccttct tcaactgatt
    55441 ttattctacc tctttgcatt cttcttgata taagttttaa ttcttttctt gccataaatg
    55501 cttcaaattc tgaatactcc tcatcaaatt catctgttag gtcgtatgtt tttctaggtg
    55561 tgatgatttt ggttttactt tctttgaatg tttctaatat gataccttgg tctttcatgt
    55621 ctccacgacc aagtctgtct aagtccatta ctaagactgc atcatattta ttttcttcaa
    55681 cttcttttag aagttcaagc attttgggtc tatgtattat actttcacca gaaactaatt
    55741 cttcttttat ctcaattaca tctaagtttt gttcttttgc tagttttagt agggttgatt
    55801 tatgtctact taaagtttca aattcgcctt gtttttctgc ctcttcatca gcacgggatt
    55861 ttcttaagta tatggcaaca ctcataataa gtaatcacac tccttatgca ctattatata
    55921 gtaaatcaat agagtttaaa atatagaaaa taagcatgtc aaaagttaat ttaactttca
    55981 acatacttat tttctataat attaatgcct tataatcctt taatatcatt tagattagtt
    56041 tttgcatatt cattatccgg gttaagttca agcgccttat tgtaagattc tctagcttta
    56101 ttaaattctg atttactcat aaaaataaca cctcttaaat tgtaagcatc actagcgtct
    56161 attttataag cttcattatt tttatctaga tattctaagg atttatcaat tgactttaaa
    56221 gcctcatcat atcgttgtaa ctctatataa atatatgatt gtgtataata tgcaagtgga
    56281 tttttatcat caatttctat agcttttttg atatcaatag cagctttatt ataatcctta
    56341 tcttcatctt tttttgtttc tgacctagcg attttgacat aattagagct aagagctctt
    56401 ttaaagtctt tatgccataa taatttatat tcattatctt cgattataaa atatctatca
    56461 aaatttgcag tatcttcttt attttcagtg atatacttta tagtatcagt ttcttttatt
    56521 ttaacaagat ttgtgtactc tttattagaa tatttgtatt tctctacttt attttcttca
    56581 ccaagtttat aatcttttag ggtttgaagt ttaaataaag tatcttgata ttcttcaaat
    56641 ttttctagac tgacactttc cttactgtct ttacttaata aattatatgc tacttcgtag
    56701 tctttgattt ctatactatc aaggtacttt ttagctactt ctgtagcact ttcttttgga
    56761 gcacatccaa ccattgatat cataattaaa aatgatacta atattgctgt tattttttta
    56821 ctgattatca taatataatc ccccttatat tgtctctcac taattttatt ttatcaccat
    56881 attctaccaa agtcattaat ttaagaatga tatttttcat taatattata ttaagtaata
    56941 ataattttta aaatttatgg taacattttc ctgaaaagta ttatataatt taggtgaaaa
    57001 tatttaagag aaggagatat tatgaaaatt aaaaaattat taacaatagg gttatcttta
    57061 tctatattta ttgctagttg ccctatatct gcaaatgctc ttgataaaat tgaatcaatt
    57121 aaaggtgcag ataaatacga aactgctggt ataattgcag acaaacaaaa ctatactaca
    57181 gctatattaa ttaatgcaga cagtacaatg gctgatggat taagtgcaag tggacttgca
    57241 ggagctataa acgctccaat tcttttgact aagaaaaata acataccaaa tgctacactt
    57301 aaaagattag aaaaggcaaa aaaagtatat ataattggag gagaaaactc tattaataaa
    57361 tatactgaaa ctgttctaaa aggcaaagga atagagatta aaagacttca aggtagtgat
    57421 agaattaaga caagctataa tgttgcaaaa gaaataaatt caattaacaa agtaaataaa
    57481 gtcatattga ctaatgcttt taaaggagag cctgatgcaa tgagtgctgc acctgtagca
    57541 gttagagata aagcagctat agtattaact gatggaaaaa gtgttccatt taatacaact
    57601 ggtgtagaaa gttatgtaat aggtggtact tcatcaatga atgacaaact agttaaggat
    57661 actaattcaa ctagattagg tgggacagat agatatgata ctaacaaaaa gataataaat
    57721 aaattttata gtggagtaaa agaattttat atagcaagtg gtactgattt agtgtatgct
    57781 cttgttggtt ctaccattgc taaaaataat gctattgtgt tagttggtaa tgatagtaat
    57841 aaaagtgtat tgaaaagtac aattaaatta actgctatag gaaatttgag tgatagtata
    57901 ttacagcagt gtttaaatgt aacaaaaaat ataggcgatt ctaatactgg aagagaatat
    57961 acagtagaag atgctgctaa tgcagtgaaa aaactattag gtgtgaagaa attttattac
    58021 gaacctaatt attcagaaga tgaagattta atatttctac tagataaaaa ttttgatttt
    58081 tcaggaaaag agtactatgt atttgcttac attaaacagg gtgcagaggg tgatgttaga
    58141 tactgtgtag ctaaaaatga tatgagcaaa gtttatacat atgatgttaa tggtaatatg
    58201 aaagtatgta atccagatga ttataaaaat aaaggaagta taacagagga acaagcaaaa
    58261 cagatagcat taaaagaatg tgctaagaga cataaagtca gtatcaataa cttagtagtt
    58321 gatatgatag attttagaga tgatatatat agtggtaatg tctatgctgt taaaatcaat
    58381 tcaaaaaata gtaatggtac ttttggttgg ttttttatag atatagaaac tgggaaaatt
    58441 tataattaaa attagaactt ttaaacaata attatataat ttaccataat atgttataat
    58501 atttttagca agaagattta acttacaatc tatagagtgg agttcatgta caaaagatta
    58561 tcctcccaac gattcgaagg gaggtgagtt catggataac tttttgttta atgttttagc
    58621 tagtttaaca gctagtgtgg tagtttactt aatcagtaaa ctattcaaaa aagcaaaaag
    58681 ccactctcgc
//
LOCUS       DAMJWO010000010        55963 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.011, whole genome shotgun sequence.
ACCESSION   DAMJWO010000010 DAMJWO010000000
VERSION     DAMJWO010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 55963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55963
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.011"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            78..194
                     /gene="rrf"
                     /locus_tag="PC366_000706"
     rRNA            78..194
                     /gene="rrf"
                     /locus_tag="PC366_000706"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            202..276
                     /locus_tag="PC366_000707"
     tRNA            202..276
                     /locus_tag="PC366_000707"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:234..236,aa:Asn,seq:gtt)
     gene            282..367
                     /locus_tag="PC366_000708"
     tRNA            282..367
                     /locus_tag="PC366_000708"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:316..318,aa:Leu,seq:taa)
     gene            383..458
                     /locus_tag="PC366_000709"
     tRNA            383..458
                     /locus_tag="PC366_000709"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:416..418,aa:Met,seq:cat)
     gene            466..540
                     /locus_tag="PC366_000710"
     tRNA            466..540
                     /locus_tag="PC366_000710"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:499..501,aa:Glu,seq:ttc)
     gene            555..628
                     /locus_tag="PC366_000711"
     tRNA            555..628
                     /locus_tag="PC366_000711"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:587..589,aa:Gly,seq:tcc)
     gene            634..709
                     /locus_tag="PC366_000712"
     tRNA            634..709
                     /locus_tag="PC366_000712"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:667..669,aa:Val,seq:tac)
     gene            715..791
                     /locus_tag="PC366_000713"
     tRNA            715..791
                     /locus_tag="PC366_000713"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:749..751,aa:Asp,seq:gtc)
     gene            802..876
                     /locus_tag="PC366_000714"
     tRNA            802..876
                     /locus_tag="PC366_000714"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:834..836,aa:Gly,seq:gcc)
     gene            886..959
                     /locus_tag="PC366_000715"
     tRNA            886..959
                     /locus_tag="PC366_000715"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:920..922,aa:Arg,seq:tct)
     gene            1935..2774
                     /locus_tag="PC366_000716"
     CDS             1935..2774
                     /locus_tag="PC366_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HDF2576256.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            2771..3952
                     /locus_tag="PC366_000717"
     CDS             2771..3952
                     /locus_tag="PC366_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576257.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVY
                     LKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKEDIDKISYIKTKPIDLADLANGE
                     EKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNIDNPNVISDV
                     DIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            4256..5158
                     /gene="ptb"
                     /locus_tag="PC366_000718"
     CDS             4256..5158
                     /gene="ptb"
                     /locus_tag="PC366_000718"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HDF2576258.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            5180..6259
                     /gene="buk"
                     /locus_tag="PC366_000719"
     CDS             5180..6259
                     /gene="buk"
                     /locus_tag="PC366_000719"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HDF2576259.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLV
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            6249..6926
                     /locus_tag="PC366_000720"
     CDS             6249..6926
                     /locus_tag="PC366_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2576260.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            6969..7184
                     /locus_tag="PC366_000721"
     CDS             6969..7184
                     /locus_tag="PC366_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2576261.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            7213..8292
                     /locus_tag="PC366_000722"
     CDS             7213..8292
                     /locus_tag="PC366_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HDF2576262.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            8292..9044
                     /locus_tag="PC366_000723"
     CDS             8292..9044
                     /locus_tag="PC366_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HDF2576263.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            9045..9602
                     /locus_tag="PC366_000724"
     CDS             9045..9602
                     /locus_tag="PC366_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HDF2576264.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            9772..11118
                     /locus_tag="PC366_000725"
     CDS             9772..11118
                     /locus_tag="PC366_000725"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HDF2576265.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGS
                     THPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILNGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS"
     gene            11385..13217
                     /gene="glmS"
                     /locus_tag="PC366_000726"
     CDS             11385..13217
                     /gene="glmS"
                     /locus_tag="PC366_000726"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003401499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HDF2576266.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEEEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELISEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIILDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKEIPSKIQEIL
                     DNEEYIKEVAKTVVSSEHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFAAGELKHGT
                     IALIEKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVEKAADKIIYI
                     PNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            13670..14965
                     /locus_tag="PC366_000727"
     CDS             13670..14965
                     /locus_tag="PC366_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase"
                     /protein_id="HDF2576267.1"
                     /translation="MTNDFKKEKKEDYFVNLKAISTEVLQEKMQDNAWVIVDTRLNDA
                     YNGWKLDGVKRGGHIKRAVDFSANWLNVYSDRKDEVLEQALKTKRIDLDKNIVLYDAN
                     GKDALVVADYLSKKGYKYLYKYDIKQWADDENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFEDSKNIKMIEASWGEESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLTKFALD
                     YGLTKDDTVIVSSITPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFISNPK
                     HSCTNFGADIPVNSQLVVTTSELRQKLKEKNKFILVDNRTWDEHIGKVSGYTYYDKKG
                     RIPGALYGHSGSNSVSLEEYRNIDNTMRNKSEILEMWDKENIDVNKQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
     gene            15449..16186
                     /locus_tag="PC366_000728"
     CDS             15449..16186
                     /locus_tag="PC366_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HDF2576268.1"
                     /translation="MKKVKLAISFFILMIIGMTISYADTSINTRYNRLSKALEISEAN
                     FKFYNVKINSVINHNLSNKEFHNIFIEIINNLKLDKKGINWNQKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGKTLIYIATPIIKLDY"
     gene            16207..17460
                     /gene="murA"
                     /locus_tag="PC366_000729"
     CDS             16207..17460
                     /gene="murA"
                     /locus_tag="PC366_000729"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDF2576269.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            17547..18611
                     /gene="spoIID"
                     /locus_tag="PC366_000730"
     CDS             17547..18611
                     /gene="spoIID"
                     /locus_tag="PC366_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HDF2576270.1"
                     /translation="MKNPLVVLLGFVTCSVLVPSLITLVSYKNVELTEKPESPVSINK
                     TIKKSDIEDKGNKEEKSTVSYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            18677..19345
                     /locus_tag="PC366_000731"
     CDS             18677..19345
                     /locus_tag="PC366_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HDF2576271.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFNDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVSVKKEQKVTEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            19443..19703
                     /gene="spoIIID"
                     /locus_tag="PC366_000732"
     CDS             19443..19703
                     /gene="spoIIID"
                     /locus_tag="PC366_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HDF2576272.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKEHKKM"
     gene            19900..20919
                     /locus_tag="PC366_000733"
     CDS             19900..20919
                     /locus_tag="PC366_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HDF2576273.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDKRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            20935..21363
                     /gene="fabZ"
                     /locus_tag="PC366_000734"
     CDS             20935..21363
                     /gene="fabZ"
                     /locus_tag="PC366_000734"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDF2576274.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEIEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(21474..21983)
                     /gene="yyaC"
                     /locus_tag="PC366_000735"
     CDS             complement(21474..21983)
                     /gene="yyaC"
                     /locus_tag="PC366_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HDF2576275.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     regulatory      22172..22275
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            22412..23605
                     /locus_tag="PC366_000736"
     CDS             22412..23605
                     /locus_tag="PC366_000736"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HDF2576276.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEETKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     gene            23921..25018
                     /locus_tag="PC366_000737"
     CDS             23921..25018
                     /locus_tag="PC366_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576277.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     IGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGTFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMAIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSNIGNIYTKEIPALYLADKISPIIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCMLYRRITKTEGYKENKSEIS"
     gene            25282..27501
                     /locus_tag="PC366_000738"
     CDS             25282..27501
                     /locus_tag="PC366_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HDF2576278.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKIYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIEVINKNPYQLAEDIRGIGFKVADSIASKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELNGEIIKECVMMLVYNQKIHIEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEEDKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMINSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVDKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEESFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYILFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPIAWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            27504..28286
                     /locus_tag="PC366_000739"
     CDS             27504..28286
                     /locus_tag="PC366_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HDF2576279.1"
                     /translation="MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYS
                     ICKSCFKEMNFIQDGCMKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDV
                     TKKMVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQK
                     IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKENVKLINNKNILL
                     IDDIFTTGLTTNEISKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            28618..30531
                     /locus_tag="PC366_000740"
     CDS             28618..30531
                     /locus_tag="PC366_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2576280.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKY
                     IDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNVSTKKGSGIYIEGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSNNIKKSLYLNEELASYTKKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            30672..30980
                     /locus_tag="PC366_000741"
     CDS             30672..30980
                     /locus_tag="PC366_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2576281.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            31005..31331
                     /locus_tag="PC366_000742"
     CDS             31005..31331
                     /locus_tag="PC366_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2576282.1"
                     /translation="MKRKVYLFCSFGMSTSLLADKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            31370..32704
                     /gene="celB"
                     /locus_tag="PC366_000743"
     CDS             31370..32704
                     /gene="celB"
                     /locus_tag="PC366_000743"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HDF2576283.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLISSPLLIIGSLFLLV
                     ANFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIVTPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSIHEFIFKFL
                     QMPLLKLGNSLGAMAIAYIFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGS
                     KIPNIITGQFQDMFATFGGAGSTLSLVIAMLLICKSKRIKSMGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFAIVPTINIIIAYFCMSAGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQLVLLILGIFMYIPFIKMLDKQYLREENETVEEEDDDISFDDLVL"
     gene            32715..33233
                     /locus_tag="PC366_000744"
     CDS             32715..33233
                     /locus_tag="PC366_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HDF2576284.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMEQFLNE
                     SKVIATLFCGDEFFVNNEKEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
                     EDITLMKEEFCY"
     gene            33329..34288
                     /locus_tag="PC366_000745"
     CDS             33329..34288
                     /locus_tag="PC366_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HDF2576285.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEDYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCAATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIKRRGKAGDLSLVAMNNKGEWGVATNIVDFTFSVV
                     TKEESPAVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            34336..35388
                     /locus_tag="PC366_000746"
     CDS             34336..35388
                     /locus_tag="PC366_000746"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HDF2576286.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISKKLGFKVRNLDNYIGYAEHGDSDDYVCVIGHVDVVHEGDGWKHQPYKGE
                     ETNGRIYGRGVLDNKGPIMSALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKTPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVYLGFIENMSENVLVTYKE
                     LNIENSNTILDIKVKYDFSYKLKDVLDEIKASFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            35391..36065
                     /locus_tag="PC366_000747"
     CDS             35391..36065
                     /locus_tag="PC366_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HDF2576287.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIESV
                     VNSVKIPVNVMIRHHAKSFVYSKEDISIMQKDIGVVKEIGANGVVFGVLDKNNNIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKILKDYDKITNILTSGGKGSIVDNIQMIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRINNSPFEDIDRQKLKQL
                     VNIISR"
     gene            36618..37169
                     /gene="raiA"
                     /locus_tag="PC366_000748"
     CDS             36618..37169
                     /gene="raiA"
                     /locus_tag="PC366_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDF2576288.1"
                     /translation="MNIIISGKQIELTDAIKNKIETKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDSEINLADEQEDYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            37301..39976
                     /gene="secA"
                     /locus_tag="PC366_000749"
     CDS             37301..39976
                     /gene="secA"
                     /locus_tag="PC366_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDF2576289.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMVREDLPDSVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            39991..41098
                     /gene="prfB"
                     /locus_tag="PC366_000750"
     CDS             join(39991..40065,40067..41098)
                     /gene="prfB"
                     /locus_tag="PC366_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HDF2576290.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNQQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEDDDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            41242..43383
                     /locus_tag="PC366_000751"
     CDS             41242..43383
                     /locus_tag="PC366_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HDF2576291.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLENLALSILENNLDNIEIEAKNYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYNEAVKSMAPHRVL
                     AINRGEKESFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVSSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DSEVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHVAGISKAIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNIGEIDEKIKEIGLRELSEKLEVGQVTLKDIIAEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMTLKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            43531..44697
                     /locus_tag="PC366_000752"
     CDS             43531..44697
                     /locus_tag="PC366_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2576292.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIDEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPIDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTCGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIVDELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKTLGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVLYTIINGKVVYEKK"
     regulatory      44757..44874
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            44999..45604
                     /locus_tag="PC366_000753"
     CDS             44999..45604
                     /locus_tag="PC366_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2576293.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPLVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVIISLVTLPLYKKMGNIIKK"
     gene            45933..46973
                     /locus_tag="PC366_000754"
     CDS             45933..46973
                     /locus_tag="PC366_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF2576294.1"
                     /translation="MHLSKKIKKLFLDDKGYYFNSNWEDIHIGIYDTKLGDSLKYITN
                     EYIENMERVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKNQTEELCLEAIKYNYK
                     ALEYVKEQTEYLCLEAIKKDCNALKYVRNKTEGLIIKAISHSSNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVKNQTEKMCIESVRQNGMA
                     LQYVNKQTDKICIEAVKQDGRSLQFVNNKTEEICINAIRYLNKKYNIKDVLSYIDKYT
                     EDICIEIVRQNGKMLMYIKNQTEKMCIEAVKENYKSLKYVKEQSERICKEALKQNHKA
                     KEYVKIAIDDCI"
     gene            47112..47564
                     /gene="tsaE"
                     /locus_tag="PC366_000755"
     CDS             47112..47564
                     /gene="tsaE"
                     /locus_tag="PC366_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HDF2576295.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIEDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDEGREMILTPKGEFYKEIVEELIK"
     gene            47564..48280
                     /gene="tsaB"
                     /locus_tag="PC366_000756"
     CDS             47564..48280
                     /gene="tsaB"
                     /locus_tag="PC366_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HDF2576296.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTVNNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     INFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVVEFDALVDEIVSTNEEFII
                     VGEAVYKYKDKLENIKNIKIPSPANNVSNAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            48270..48746
                     /gene="rimI"
                     /locus_tag="PC366_000757"
     CDS             48270..48746
                     /gene="rimI"
                     /locus_tag="PC366_000757"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDF2576297.1"
                     /translation="MEDNTKLIVDDIKIEEMTTEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLNGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKCIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            48752..49768
                     /gene="tsaD"
                     /locus_tag="PC366_000758"
     CDS             48752..49768
                     /gene="tsaD"
                     /locus_tag="PC366_000758"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HDF2576298.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREVLSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANIGFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAKNGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSNKALKAVKDKGYNIITLSGGVAS
                     NSGLRAKITELAKDNGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            50065..52773
                     /gene="hpdB"
                     /locus_tag="PC366_000759"
     CDS             50065..52773
                     /gene="hpdB"
                     /locus_tag="PC366_000759"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HDF2576299.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQ
                     KTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDHRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            52777..53034
                     /gene="hpdC"
                     /locus_tag="PC366_000760"
     CDS             52777..53034
                     /gene="hpdC"
                     /locus_tag="PC366_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HDF2576300.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDSACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            53027..53977
                     /gene="hpdA"
                     /locus_tag="PC366_000761"
     CDS             53027..53977
                     /gene="hpdA"
                     /locus_tag="PC366_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HDF2576301.1"
                     /translation="MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNIHTAIETSACVSNEVFNKIFKDIDFAFIDIKHMDREKHKEQTGVYNDLILENIS
                     NLANSDWNGRLVLRVPVISGFNDSAENISDIISFMHKNNLIEINLLPFHRLGESKWIQ
                     LGKEYEYSDKGDIDEEHLEELQDIFLDNGIACYVGHETAF"
     gene            54297..55259
                     /locus_tag="PC366_000762"
     CDS             54297..55259
                     /locus_tag="PC366_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2576302.1"
                     /translation="MNKSWSNLIIKNKDKKVRSGWIIITVMAAFYIFEYYLSTILMEI
                     IRKILIATGDINLKTNYFSEYANWLNDVGLQVVFQILTDSLMIIIPIIVWRFIMKNPI
                     SEMGLHSYRIKKKEGYVGMLLGIFNCTVIFIITITIGGGHVTSWVPKISPLTVSWILV
                     FILVAFAEEILNRGFFMAVLRRCKNIYFIMIVPSVIFGLIHIWNPDVTFLSVINIIII
                     GILFSYMFIKSSNIWMCIGYHFTWNVFQGIIYGMPVSGLQVPGIITTQITHGNLLNGG
                     MFGIEGGILTTFVNLLSFIFVWYYYRDSKYDFVSDKVNVTNIKN"
     gene            complement(55358..>55963)
                     /locus_tag="PC366_000763"
     CDS             complement(55358..>55963)
                     /locus_tag="PC366_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2576303.1"
                     /translation="LSIIIYSSNKKNLYPVKNIKLGSLLIIYFMISVIVPTSFILILQ
                     GAQPNYSGIIKFIFTPITSLTTIYIFFSEEYAWRGFLQNIFFDKFGKKLGVIILGMCW
                     SLWHLPLIFTLYTPEAPILGVILRSIHIVGISIFLGYLYIKTKNIWFCAIIHVLNNSA
                     FLITNSKESTITYHDILIVSMVVLIFYVPFLFTKEYKNNLE"
BASE COUNT        22408 a         6054 c        10638 g        16863 t
ORIGIN      
        1 taactctaaa gaaactagta ttgctaggtt ctataaactt attaaaaact taatagaaat
       61 attaagcata aagattatgt ggttacaata gcagagagga tacacctgtt cccattccga
      121 acacagaagt taagctctct agcgctgatg gtacttggtg ggaaactgcc tgggagagta
      181 ggacgtagcc acgttaaatg ttccaaggta gctcaacggt ggagcaaccg gctgttaacc
      241 ggtaggctgt gggttcgagc cccacccttg gagccaaaaa agccgaagtg gcggaactgg
      301 cagacgcaca ggacttaaaa tcctgcggga cttacctctc gtaccggttc gattccggtc
      361 ttcggcactt ataaaacaat atcgcggggt ggagcagttg gcagctcgtc gggctcataa
      421 cccgaaggtc gtaggttcaa gtcctgcctc cgcaaccatt aaaacggctc gttggtcaag
      481 aggttaagac accgcccttt cacggcggta acaggggttc aattccccta cgagtcacca
      541 attcaattaa atatgcgggt gtagctcaat ggtagagttc tggccttcca agccagctgt
      601 gagggttcga tccccttcac ccgctccaaa aatgggacca tagctcagct gggagagcac
      661 ctgccttaca agcagggggt cacaggttcg agccctgttg gtcccaccat tcgcggcctg
      721 gtagttcagt tggttagaat gccagcctgt cacgctggag gtcgagggtt cgagcccctt
      781 ccaggtcgcc aaattaaata agcgggaata gttcagtggt agagcgcaac cttgccaagg
      841 ttgaagtcgc gagttcgaat ctcgtttccc gctccataat aacttgggtg catagctcag
      901 ctggatagag caacgccctt ctaaggcgtg tgtccggggt tcgaatccct gtgcgctcat
      961 taagaaaagt ttactataaa ttatagtaaa cttttatatt gtttaaaaag acacaggaaa
     1021 catgtatatt acctgtgtct ttttatttat aaactttaaa ctatgtaaaa attacagtat
     1081 attctaatag agttacagta tattcattaa tattgtaaac atacggaggg taatgtataa
     1141 tagtctacaa gatgtttatg aaggcatcag ttaaatataa ctaattagat aagagttata
     1201 tacattatat tgtatacttt atggtattta tatattgaaa taacttatga aattatttat
     1261 aaagagattt atgagcatat ttttgtctaa acaataagta taagaaatta taaaaaatta
     1321 gagactatag tgaattgaca atttaatgta atatttataa gttatactaa gtaaattatt
     1381 atactgtgaa atggatatat aactttaggt attgtgtatt attttcactg taggagatta
     1441 tatctagtta tacataataa gttttaatga tagtttatag taagatatta aaataaattt
     1501 atctaatcta gatatgaaat aagttattac tttaatataa aaatgaatct aatggaataa
     1561 tattgatgat aagtaatatt tagattttgt atttgtttat agttaataag tggattatag
     1621 aatttataat aattaatata tattaaacaa agatatatta agatatttta gaacataaaa
     1681 ctgcattaag gcgcgagtac tattttgtat tcgcgccttg atggtttgag ttatttgagt
     1741 aaaaactaac tttaataaga aatatgtatt tattaagttg atatttttaa tgtgtttaga
     1801 gattatttaa caatctccaa atataaaact agaattattt acataaaagt taaatagttt
     1861 gtatagagtt agatttatat agtataatac ttagtgtaaa taattaagaa gttatcaaac
     1921 aggaggataa aactgtgtta gatataaatt cttttttaaa tggatttttt aatataatat
     1981 taagaatgag tatatatgat ttaattgaca tatctatagt agcgtatatt ttttacaaaa
     2041 tatttatgtt tataaaagat acaagagcag aacaagtgtt taaaggtata atatttcttt
     2101 tattagcaac tcaacttagt aacaccttta aattgcatac cgtttattgg atatctctta
     2161 aagctttaga ttatggagtt atagctgctc ttataatttt tcaaccagaa tttagagcag
     2221 gacttgaaca tataggaaga gcaaagttta atttatttgg aaagaatgta aatacttctg
     2281 aagaaactct caatagaaat atagaagaaa ttgtagaagc tttatattca ctttctagac
     2341 aaaaaatagg agctcttatc ataatggaga gagaaactag aataagtgat ataataaata
     2401 caggaactat tattgatgct gaaatttcta ggcaactatt aataaatata tttataccaa
     2461 atacaccatt acacgatgga gctgttgtaa ttagagattc taaggtaaaa gcagctgcat
     2521 gttttttgcc attgacggaa agtaaggatt taagtaaaga tttgggtact agacatagag
     2581 caggaatagg ggtaagtgag gtgtctgact gtataactct gattgtatca gaggaaacag
     2641 gtggcgtatc aattgctaaa gcaggtaagt tatatagaga tatttctaga gaaagaatga
     2701 tgaatatatt acgtagtaat ttaaaaacaa atacagaaac aagaagtttt ttcaaaggtg
     2761 gtatatttaa atgataaata gactaaaaaa taataccaaa ataaaaataa tatcattttt
     2821 aagtgcaatt gcattatgga tgtatgttat ggctgtagtt gaccctgaag aaactaaagg
     2881 gtttgaagat atacctgtat ctataagtaa tatgagtgat ttaaaggata aaaatcttgt
     2941 tatatatcca gacgaaaaat taacagcaga tgtatatata aaaggtagtt tatcaaaggt
     3001 acaaagtgtt aagaaagaag atatacatgt atatggaacc attgaagacc caatacaagg
     3061 acagaaggaa gtatatttaa aagcaaatat tcctcaaggt gttactctag aatttaagca
     3121 tgatgtttta gtagtaaatc ttgaaaaaaa cataaaagaa aaaagagata taaaggtaga
     3181 agtaagtgga aattcaaaaa gaaatataaa taaaattgaa cttagtaagg aatttgtcga
     3241 tgtatcaggt ccaagaactc tagttaaaga agtcaaaagt gtaagagcta atctagatgt
     3301 tggtaatgag acagatgatt tttctaaaaa attgcaatta ataccattaa atagtgatgg
     3361 aactaaggtt gaaggagtaa cattaagttc atcctttgtg actgcaaaga tagaactatt
     3421 gaaggaaaaa attgtcccaa taagagtaag tctaaatgat aataaagata atgatgtact
     3481 gaaaaactat aaattaagta aggaacaagt tacaataaaa ggaaagaaag aagatataga
     3541 caaaataagt tatattaaga caaaacctat tgacttagct gatttggcta atggtgaaga
     3601 aaaagaagtt agcttagaaa ttccagaggg tataactctt gaggatagct ctataacaat
     3661 taaattaaat gatacaaaac aattgagtgc agaattttta tataatgcgg gagatattga
     3721 attaagaaat atcccaacaa atatagataa tccaaatgta atttctgatg tagatataaa
     3781 agttgttgta gagtcaacgg aggatttgag taagttaaat aaaaaagata tttcattata
     3841 tattgattta tcacaaggcc ctgaggaaga tagtaaatat aaaataaaat atgaaacaac
     3901 atatcaattt aaaaaaataa atatagaacc taatattgtt gaagtggaat gaacaaatat
     3961 ttcgaatatt tagttgttac aagatgcgac aaaaaaacct ataaaattaa gtttgttaat
     4021 tttatgtttt tgttgcatct tgtttatttt agttatatta taaaataagg acaatgagat
     4081 atttgttaaa tctaaaaagc gctagatata tgaaaaaaga ctgataaata gatttaaata
     4141 aatattttga attaaatatt tcaattatct ctaggaaaac gttgctgaac gagttataat
     4201 ttaattgaga tataaaaagt tctatttcaa aaaattcaag atgaggtgga aatgcatgag
     4261 aagttttgaa gaagtaatta agtttgcaaa agaaagagga cctaaaacta tatcagtagc
     4321 atgttgccaa gataaagaag ttttaatggc agttgaaatg gctagaaaag aaaaaatagc
     4381 aaatgccatt ttagtaggag atatagaaaa gactaaagaa attgcaaaaa gcatagacat
     4441 ggatatcgaa aattatgaac tgatagatat aaaagattta gcagaagcat ctctaaaatc
     4501 tgttgaatta gtttcacaag gaaaagccga catggtaatg aaaggcttag tagacacatc
     4561 aataatacta aaagcagttt taaataaaga agtaggtctt agaactggaa atgtattaag
     4621 tcacgtagca gtatttgatg tagagggata tgatagatta tttttcgtaa ctgacgcagc
     4681 tatgaactta gctcctgata caaatactaa aaagcaaatc atagaaaatg cttgcacagt
     4741 agcacattca ttagatataa gtgaaccaaa agttgctgca atatgcgcaa aagaaaaagt
     4801 aaatccaaaa atgaaagata cagttgaagc taaagaacta gaagaaatgt atgaaagagg
     4861 agaaatcaaa ggttgtatgg ttggtggacc ttttgcaatt gataatgcag tatctttaga
     4921 agcagctaaa cataaaggta taaatcatcc tgtagcagga agagctgata tattattagc
     4981 cccagatatt gaaggtggta acatattata taaagcttta gtattcttct caaaatcaaa
     5041 aaatgcagga gttatagttg gggctaaagc accaataata ttaacttcta gagcagacag
     5101 tgaagaaact aaactaaact caatagcttt aggtgtttta atggcagcaa aggcataatt
     5161 ttaaggggga aataggcaaa tgagcaaaat atttaaaatc ttaacaataa atcctggttc
     5221 gacatcaact aaaatagctg tatttgataa tgaggattta gtatttgaaa aaactttaag
     5281 acattcttca gaagaaatag gaaaatatga gaaggtgtct gaccaatttg aatttcgtaa
     5341 acaagtaata gaagaagctc taaaagaagg tggagtaaaa acatctgaat tagatgctgt
     5401 agtaggtaga ggaggacttc ttaaacctat aaaaggtggt acttattcag taagtgctgc
     5461 tatgattgaa gatttaaaag tgggagtttt aggagaacac gcttcaaatc taggtggaat
     5521 aatagcaaaa caaataggtg aagaagtaaa tgttccttca tacatagtag accctgttgt
     5581 tgtagatgaa ttagaagatg ttgctagaat ttctggtatg cctgaaataa gtagagcaag
     5641 tgtagtacat gctttaaatc aaaaggcaat agcaagaaga tatgctagag aaataaacaa
     5701 gaaatatgaa gatataaatc ttatagttgc acacatgggt ggaggagttt ctgttggagc
     5761 tcataaaaat ggtaaaatag tagatgttgc aaacgcatta gatggagaag gacctttctc
     5821 tccagaaaga agtggtggac taccagtagg tgcattagta aaaatgtgct ttagtggaaa
     5881 atatactcaa gatgaaatta aaaagaaaat aaaaggtaat ggcggattag ttgcatactt
     5941 aaacactaat gatgctagag aagttgaaga aagaattgaa gctggcgatg aaaaagctaa
     6001 attagtatat gaagctatgg catatcaaat ctctaaagaa ataggagcta gtgctgcagt
     6061 tcttaaggga gatgtaaaag caatattatt aactggtgga atcgcatatt caaaaatgtt
     6121 tacagaaatg attgcagata gagttaaatt tatagcagat gtaaaagttt atccaggtga
     6181 agatgaaatg attgcattag ctcaaggtgg acttagagtt ttaactggtg aagaagaggc
     6241 tcaagtttat gataactaat gataaaagaa taagaatcat aactggtcac tatggaagtg
     6301 gtaaaagtga atttgcgatg aactatgttg ttaagttaag agatatggtt tctggcaaag
     6361 ttgctatagc cgatttagat gtggtaaatg tatactttag aactagagaa aagaaagagt
     6421 taatgaaatc cttaggtata caaccaatag atagctcaat taatgctcca acattagatt
     6481 taccagcagt atcagcagag gtaatgtctc ctatggtaga ccattcatac aattctgtta
     6541 tagatttagg tggagataat gtaggtgcta gggttatagg aagatttagt catttgttaa
     6601 aagaaggcga ttatgatatg ctttttgtaa taaatgcaaa tagggagaaa actcaaactt
     6661 ctgaagaagt tatccaatat ataaaagaaa tagaaaaatc ttctaaatta aaggtaacag
     6721 gtctaattaa taatactcat cttattaggt ttactactat tgatgatgtt ttaagaggtc
     6781 agaaagttgc aaaagaagtt tctgaaaaat gtaatatacc gataagatat gttgcatgtt
     6841 tagaaaatct tgttgaacag ttaccaaaag atttagaagg agaaattttt cctataaaat
     6901 tatatatgag agaagactgg atgtagtttg agctcaaata tatagaaagt ttaaggaggc
     6961 ttaggtaaat ggctaaagga aaagtatctt ttaatcaaga acgttgtaaa ggttgtggat
     7021 tgtgtgttga agcatgtcca gtaaaaatca tacaattaga ctcaaatgta ataaacaaaa
     7081 aagggtataa cccagcaact gtttttgaaa tggaaaaatg cataggatgt gcaagttgtg
     7141 caactatgtg tccagatgta gttataacag tagaaagaga ttaatttaat taatatttaa
     7201 gggggaattt taatggctaa gatacttatg aaaggtaacg aagcatttgg aaaagcagct
     7261 atagaagctg gttgcaaata tttcttcggt tacccaataa ctccacaaag tgaattacca
     7321 gaatatttat caagagagtt acctaaaata ggtggagcgt tcgttcaagc tgaatcagaa
     7381 gtttctgcga taaacatggt ttatggtgga gcaggtgcag gagcaagagt tatgacttct
     7441 tcatcttcac caggagttgc tttaaagcaa gaaggtataa catatgcagt aggagcagaa
     7501 gttccttgtg ttgtacttaa tgtaatgaga ggtggtccag gacttggaag tatacaacct
     7561 tcacaagctg actactttat gtctacaaga ggtggaggaa atggagacta cagaactcca
     7621 gtattcgcac cagctacagt tcaagaagct gttgatatga taatggaagc ttttgacgtt
     7681 gcagattatt acagatcacc agttatggta gttgcagatg gtatgatagg tcaaatgatg
     7741 gagccagttg aatttagagc tcctgagaag aaaagagaat tgcctcctaa agattgggca
     7801 actgttggaa ctaaaggaaa aagaaaacct aatgtaataa actctctata cttagaacca
     7861 gaagtactag aagaccattg ttggcattta caagaaaaat ttgatgcaat ggaaaagaat
     7921 gaagtacaat acgaaatgta caaaacagaa gatgctgaat ttgtatttgc agcttatgga
     7981 actacttcaa gagtagtaaa aagcgcaatt gatatattaa gagaagaagg aataaaagca
     8041 ggtcttataa gacctaaagt attatggcca ttcccattcg aagcattcaa ccaaattcct
     8101 aatgctagaa acatattgac tgttgaaatg agtatgggac aaatggtgga agatgttaaa
     8161 atggcagtag aaggtaaatt accagtttac ttccatggaa gaccaggagg aatgactcca
     8221 acaccagcag aaatagttga aaaagctaaa aaaattattg ccggagaatt ggttgcagga
     8281 ggtgctagat aatggctgtt gtatttaaga aaactgaagg attacaagat actcaaactc
     8341 actactgtcc aggatgtaca catggtataa tccatagatt agttggtgaa gtattagaag
     8401 aactaggagt attaggtgat gctgtaggtg ttgttccagt tggatgttca gttttaggat
     8461 ataaatattt taactgtgac actcaagaag ctgctcatgg tagagcgcca gctgctgcta
     8521 caggaataaa aagagttcat cctgaaaata cagtattcac ttatcaaggt gatggagact
     8581 tagcttcaat tggtactgct gaaatagttc atgcagctgc tagaggagaa aaaataacta
     8641 ctatatttgt aaacaataca acttatggta tgactggtgg acaaatggct ccaactacat
     8701 tagttggaca aagagctact actgctcaat caggaagaaa tgctgaaact caaggttatc
     8761 caataagagt aagtgaaatg ttagctacat taacaggagc tgtatttgta gaaagagtag
     8821 cagttgatac tccagctcat gttagacaag ctaaaaaagc tataaagaaa gcattccaag
     8881 ttcaacaagc aggattagga tttggaatag tagaagtatt atctacttgt cctacaaact
     8941 ggggactagc tccaaacgat gctttacaat ggttaagaga caacatgata ccatactatc
     9001 cattaggaaa tttcaaaaat gttgaagttg aggaggtgaa gtaaatgtct acagctagag
     9061 taatatgtgc aggcttcgga ggccaaggtg ttatgtctat gggacaatta cttacttatg
     9121 caggaatgct agaaggaaaa gaagtttctt ggttaccatc ttatggacca gaaatgcgtg
     9181 gaggtacagc aaactgtgca gtaactgtat ctaatgagcc agttggttct ccacttataa
     9241 cagatgatgc aactgcagct atattattaa atataccagc atttgaaaaa ttcaaagatg
     9301 atgttattcc tggtggaaaa ataatagtaa atagttcttt aataaaagaa aaagttgata
     9361 gaacagatgt agatgtttat tatataccag caaatgaatt agcagctgaa ttaggaaatg
     9421 ataaagttgc taatatgata atgttaggcg cttacttaaa agtatctgat actgtagata
     9481 tagaatctgt actagaagca ttcaaaaaag ttttcggacc tagaaaagaa aaattcgttc
     9541 cattaaacag agaagcttta caaaaaggta tggatgctac atgttctaaa gcaactaact
     9601 aataaagaaa aagatgtcaa aaaaaagaca atagaattat ttctattgtc ttttttgctg
     9661 ataagtatta aaatgttttt atgactgaaa ttaagcctat aatgatattt tatgaactat
     9721 aaaaatataa tacaaattac aagcttttca attatgaaag gagaatcttt agtgagaaag
     9781 tattttggaa cagatggagt tagaggagta gcaaatacag aactaacatg tgatttagca
     9841 tataaacttg gtagagctgg tggatttgtc ttagctcaag gagaccacag agtaaaagta
     9901 gtagtaggta aggatactag aatatcaggt gatatgttgg aagcatcttt aatagcagga
     9961 cttatgtctg ttggatgtga tgttattact gttggaataa taccaacacc tgcagtggca
    10021 tatttaacta gaaaatatgg tgctgattgt ggtgtggtta tatctgcatc tcacaatcct
    10081 gttgaatata atggaatcaa attctttaat aagaatggat ataaattaga tgatgaaatt
    10141 gaattgaaaa tagaagaata tatagacgat atagacaaaa ttgattgtct tccaattggt
    10201 gaaaatgtag gaagaaaatt acatgaacat tgtgcacaaa gagactatgt agactaccta
    10261 aaatcaataa taagcactga ctttaaggga ttaaaagtag ttttggactg tgctaatggt
    10321 gcgtcatata aagtggcacc aatagtgttt gatgaactag gagcaagtgt aatttcaata
    10381 aatagttcac cagatggaaa taatataaac tataaatgtg gctctacaca tccagaacaa
    10441 cttcaaaggg ctgttttgga acataatgct gacttaggtc ttgcatatga tggagatgct
    10501 gatagattaa ttgcagtaaa tgaaaagggt caaattgttg atggagacca tataatgata
    10561 ttgagtgcct taaatttaaa gaaaaataat aaattggcgc aagatacttt ggtagttaca
    10621 gttatgagta atatagggtt gacaatagct gctaaggaaa atggaataaa tttatctact
    10681 acagcagttg gagacagata tgttttagaa gatatggtta aaaatggata taatcttggt
    10741 ggagagcaat ctggacatat gatattttta gattacaaca ctactggaga tggagtgctt
    10801 agttctctaa tacttgcaaa tataatcttg caagaaaaga aacctttatc agaaattgca
    10861 tcaataatga gccaataccc acaagtatta gtaaatgcaa caataaaaaa tgaaaataag
    10921 aacaaatata tggaatatcc agaaataaaa actgagatag aaagaataga atctatttta
    10981 aacggaaatg gtagagtttt gataagacca tcaggaactg agccattagt tagagttatg
    11041 ttagagggta aagaggaagg tcaaataaaa gaattagcaa caaacttagc taatcttata
    11101 caagaaaaat tatcgtaatt taaagggtat tctcagatac aaatactgag gacacctttc
    11161 taagcgccag aacttagtta tagacataat tattgagtaa tataggaact aagttgacga
    11221 ggtcagagtt aatcgaattg tcggcggatg ctctgcggtg tgtttaccat cgaaagactt
    11281 ctttaaataa taggagcaat cctatggaca aagggaagcc aaagtaaact tatatgacct
    11341 aactcttaaa atatataaat aatattttta ggaggacaca aataatgtgt ggaatagttg
    11401 gatatttagg aagtagaaag gcagcagaag ttatagtaga agggctttct aagctagagt
    11461 acagaggtta tgactcagca ggagtagcag ttaatagttc taatgaagaa gaacttaata
    11521 ttagaaagtt taaaggtaga ctttctgtac ttgcagaaga cttagaaaag aatcctattg
    11581 atggaaattt aggtataggg catacgagat gggcaactca tggagaacca tctgatgtaa
    11641 actcacatcc tcattttaat caagccaaaa caatagcagt tgttcataat gggataatag
    11701 aaaactatat ggaaataaaa gaagaattaa tttctgaagg tgttaagttt gaatctcaaa
    11761 cagatacaga ggtaatagca catttagtag ataaatacta tgagggtaat ttattagatg
    11821 ctgtatacaa aactatatca aaattaagag gagcttatgc attaggtgtt atatgtaaag
    11881 aacatggaaa tgaattagtt gcagtaagaa aagatagtcc tcttgtagtt ggtgttggtg
    11941 aaggtgaaaa ctttatagca tcagatatac ctgcattatt aaaatatact agagatgttt
    12001 atttcttaga aaatggagaa gtagttcatc taaaagacga aaatgtaaca gtttatgact
    12061 ctaatagaaa tcttgttgaa aaagaagtat ttcatgtaac ttgggatgta gaagctgcgt
    12121 ctaaaggtgg atatgactac tttatgtcaa aagaaattca tgagcaacca acaggagtta
    12181 gagaaacttt agaaagaaga cttgatgata atggaaatat aattctagac agtataaata
    12241 tttctaaaga agacttagaa aaaataaata aagtttatat agtggcttgt ggaacagcat
    12301 ataatgctgg attacttggt aagtatgcca tagaaaaatt tgtaaatata ccagtaataa
    12361 ctgatatagc atcagaattt agatatagcg acccatttgt agatgaaaat tcattagtaa
    12421 tattagttag ccaatctggt gagacagcag atactctagc agtattaaga gattcaaagg
    12481 ctaaaggagc aagaatactt tcaataacta acgttgtagg ttcatctata gcaagagaat
    12541 cagatgatgt attctatact tgggcaggac ctgaagtagc agttgcatca actaaggcat
    12601 atactactca aataacttct ttatacatga tagctttaga ctttgctatc aaaaaaggaa
    12661 caataactag agaattttat gatagtatga tttctaagat gaaagaaata ccatcaaaaa
    12721 tacaagaaat attagacaat gaagaatata taaaagaagt tgctaaaaca gttgttagtt
    12781 ctgaacatgc attctattta ggaagaggta tagactatag cttagcaatg gaaggttcat
    12841 tgaaattaaa agagatttca tatatacatg cagaagcttt tgcagcagga gagctaaagc
    12901 atggaacaat agctttaata gaaaaaggaa ctcctgtaat tgccatagct actcaagaaa
    12961 agttatttga aaaaatggtt tctaatatgg aagaagtaag agcaagagga gcttatgtag
    13021 tagcaatagc tcaaagccat aataaggatg ttgagaaagc tgctgataaa ataatctata
    13081 taccaaattc agatgatatt ttatcaccaa tattagcagt tgtaccaatg caattacttg
    13141 cgtatcatgt ctctgtacta agaggatgcg atgtagataa gccaagaaat ctagctaaat
    13201 cagtaacagt tgaataaaaa cagattaaaa attaaataga taatatttat tgaaaaaaac
    13261 tcatcctgtt atttgtattt tataggatga gttttttaga taaatattaa atttgttttg
    13321 tttttgctat aataaatttt ataaaaagat tgatattaaa tcatctgtaa aatgataaat
    13381 atatagacca taccaggtat agggaacgat aaatatagtt catataaaat atagtgagta
    13441 cttaataaac atatagtcaa tatcagacat aaaaaaataa tagcttatga gaaaaattaa
    13501 aatacaaggt attagtaacc ttgtgataag ataaagtgag tagtttaaaa taagaatata
    13561 aggaactatt tataaaagaa tataatgaag ctaatagagt ataagaaaat tactttattt
    13621 tagtaaaata atttcaaata aaaatttttt taaattggga gtataaatta tgacaaatga
    13681 ttttaaaaaa gaaaagaaag aagattattt tgttaatctt aaggcaatat ctactgaagt
    13741 tttacaagaa aaaatgcaag ataacgcttg ggttatagtt gatactcgct taaatgatgc
    13801 ttataatggc tggaagttag atggagtaaa aagaggtggg catataaaaa gagcagtaga
    13861 tttttctgct aattggttaa atgtatactc agatagaaaa gatgaagtgc tagaacaagc
    13921 attgaaaact aaaagaattg atttagataa aaatatagta ttgtatgatg caaatggaaa
    13981 agatgctttg gttgtagcag attatttatc taaaaaagga tataaatatc tatataaata
    14041 tgatattaaa caatgggcag acgatgaaaa tcttccaatg gaaagatata aaaattatca
    14101 aatgatagtt cctgctttta taataaaaga tatattagat ggaaaaattc ctgagacatt
    14161 tgaagattca aagaatataa aaatgattga agcgagttgg ggagaagaat cgtatacaaa
    14221 agggcatata cctacaagtg ttcatgtaaa tactgatatt atagaacctc ctccaacatg
    14281 gatgcttgat aatgatgata acttaactaa gtttgcttta gactatggac taacaaagga
    14341 tgatactgta atagtttcaa gtattacacc tatggcatct tatagactag ctgttatatt
    14401 gagatatata ggagtaaaag atgtaagagt tttgaatggt ggaacaaact catggttatc
    14461 agcaggatat gaattagaat ttattagtaa tccaaaacat tcatgtacta attttggagc
    14521 agatatacca gttaactcac aattagttgt tactacatct gaattaagac aaaaactaaa
    14581 agaaaaaaat aagtttatac tagtagataa tcgtacttgg gatgaacata taggaaaagt
    14641 atctggatat acatattatg ataaaaaagg gcgtatacca ggagctttat atggacattc
    14701 aggtagtaat agtgtttcac tagaagaata tcgtaatatt gataatacaa tgagaaataa
    14761 atctgagatt ttagaaatgt gggacaagga aaatatagat gtgaataaac agcttatatt
    14821 tatgtgtgga agtggatggc gtgctgctga agtattaaca tatgcaaatg tcataggagt
    14881 ggaaaatacc tccctttata gtgatggatg gatgggctgg agtcttgata attcaaattt
    14941 aattgaagtg ggagaacaca aataaagttt ttgaaagtac aatagagttg tttaaaacaa
    15001 aggtgttttt gatttattag gaagagtgtg taaattgtgt attgggaagt gtacttaggt
    15061 atgttcattt ggagctatgg aaattgataa aaaagtatta tctgtttatt ttgctggtaa
    15121 aatatgaata gattatagat tatagattat agattataga ttatagatta tagattatag
    15181 attatagatt atagatttaa gtatagacta agtaatttat attacagaag ataatatata
    15241 agaattaatg caagatgtat ttgatacata taaggaattg gcaagtccag gagaaggata
    15301 gagaaaattg agattgaaga gtttgaaaga gattattaga tgaaaaatac aaaaatgtat
    15361 aaaaatacat attgagaaag tatatctctc ttaaatttgt taataattct attatacaga
    15421 aaaacatatt taagggggat tttttactat gaaaaaagta aaattagcta taagcttttt
    15481 tatattaatg attataggaa tgacaatatc ttatgcagat acaagtataa atactagata
    15541 caatagatta agtaaagctc ttgaaatatc agaagcaaat tttaaatttt ataatgttaa
    15601 aattaattct gttataaatc ataatttatc aaataaagaa tttcataata tttttataga
    15661 aataattaac aatctaaagt tggataaaaa aggaataaat tggaatcaaa aagggtctgg
    15721 cgataaaata caattatgtg ctactataaa aggtagcgat aaagaaattt ctataaaagg
    15781 aataaataaa aataacaaag aaagttacat agtagttgac atattggata acaaagtata
    15841 taaacataaa gaggttattt atagtaacgt agaaaatgtg ttaaataaat attcatctca
    15901 agtagatgtg tctgcttgta ttgttggaga atacacaaaa aggttacaaa acaacaaata
    15961 tgatgatatt ttacaaaaaa tattatataa tatgagtgct aagcaaatag atgaagttaa
    16021 agacgtaaac tttttatcta taacagcata tagtaaagta ttaaatgatt atgaattaga
    16081 atatttaggg gaaaaaatta atttaaatat aggaattaaa tataatgagg atgacggaaa
    16141 aacactcata tatattgcca caccaattat aaaattagat tattaattat gaggagatca
    16201 aaaaatatgg ctaagataat agtaaaaaag agtaatccac ttaaaggtag tgttaaaata
    16261 gatggtgcaa aaaatgcagt tttaccaata atagcagcga ctttattagc aaacggaaaa
    16321 tcaacattaa atggagtacc aaatttaaga gatgttcatg ttatatcaga tttattaaga
    16381 catgtaggag cagaagttga atataaagaa aatacactta ctgttgatgc aagcaatata
    16441 aaaacttgtg aagctccata tgagcttgta agaaagatga gagcttcttt tttggttatg
    16501 ggaccattgc ttgctagatt taatagtacg aaaatttcta tgccaggagg atgtgctata
    16561 ggaacaagac ctatagattt acatttaaaa ggatttaaag ccttaggtgc aaagatagaa
    16621 atggaccatg gttttgttga agcagcaaca gaaaagttag taggaaataa attatattta
    16681 gatttcccat ctgttggagc aactgaaaac ataatgatgg cagcttcttt agcagaaggg
    16741 actacaataa tagagaatgc agcagaagag ccagaaatag tagatttagc aaacttcttg
    16801 aacgaaatgg gagcagatgt taaaggtgca ggtactaata ctataaaaat aaaaggtgtt
    16861 aaagagttaa aaggagcaga acataatgta attccagaca gaatagaagc agcaacttat
    16921 atggttgcag cagctatgac aaaaggtgat ataactgttg aaaatgtttt aatggagcat
    16981 ttaaaaccag ttgtagctaa attaagagaa gctggttgcg aaataacaga aatggacaat
    17041 tctgtaagag ttgtaggtcc aaaagtatta aaaccaatag atataaaaac tttaccacat
    17101 ccaggatttc ctacagatgt tcaagcacaa tttatggcta tgcttactgt agccaatgga
    17161 actggtgtag ttatagaaac tgtttttgaa aatagattta tgcatgttgc tgaatttaat
    17221 agaatgggtg ctaatataaa aatagatgga agaagtgcgg ttgttaatgg tgtagatgag
    17281 ctacacggtg cagcagtaaa cgctactgat ttaagagcgg gggcagccct tattttatgc
    17341 ggtcttatag cagaaggaga aactcaaata ggagaaatat accatatcca aagaggttat
    17401 gttgatatag ataagaagat aacagcacta ggtggtcaaa tcgaaatagt agaagattaa
    17461 taattggttt atagaagaaa gttataaatt aatagggttg ttcatatact taaatacaag
    17521 gttttaaaag ctaaggagga gagtatatga agaacccatt ggttgttttg ttaggatttg
    17581 tgacttgctc tgtgttagtt ccatcactta taactttagt ttcttataaa aatgtagaat
    17641 taactgaaaa accagagagc ccagtatcta taaacaaaac tattaaaaaa agtgatattg
    17701 aagacaaagg taataaagaa gaaaaaagta cagtgagcta tgaaactgta aataaaaaag
    17761 caccaattat caatgtatat aatcatataa cagggaaaac cgaaaagatg gacatggaga
    17821 actatttatg tggagtacta gctggtgaga tgtcttcaga gtttgatata gaagctttaa
    17881 aagctcaatc tgtagcagct agaacatatg tagtatataa acaggaacat ggtaaatcta
    17941 gtaaacataa aaatgcagta gtatgtactg attataaaca ttgtcaagaa tataagagtt
    18001 atgatactct taaaaaatta aatggtgaag aatggattaa gaataaatat tccaaaatcc
    18061 aagaagcagt tagaggaact aaaggtcaaa taataactta taatgataag gcgatacttc
    18121 ctctttattt ttctacatct tcaggaaaaa cagaaaatag tgaagaagta ttttctgcaa
    18181 aatatcctta tttaaagtct gtggaaagtc cttatgataa gtattcccct aaatttgcgt
    18241 caacacttaa aataagtaac acagattttg ttaaaagtct tagaagggca tatagcacta
    18301 ttgtgataga tgtgaataat ttaagtaaac aagtttcaat aactaaaaga agtgatgccg
    18361 gaactgtaga aaaaataaaa ttaggaaata aagaattgac tggaaaagac attagaactg
    18421 tttttaaatt gaactctgca aactttgaca taaaatttgg agaaggatac atagatttcg
    18481 tggtaaaagg atatggtcat ggtgttggta tgagccagtg gggagcagaa ggaatggcag
    18541 aagagggcta taaatattat gatatattat cacattacta cacagataca aaaataaaag
    18601 atatatacta ataattgtat aaaatgccaa aaacacgtca ataatccaaa tgtagaaata
    18661 tatttggagg tgcaaaatga agaaaaagct gttagaaaaa gatggttttt atttatcttt
    18721 gtttgtatgt gtttgtttat tagcagtagg tggagtttgg tttacaaata ataatgtaga
    18781 taaattggct tctaataaag gaattatgga aaatgctaat aaagatagtg aagaggaaat
    18841 acatttaatt gaaaaagaca agaaagatgc tatccctact gcaacggatt caaaacaaaa
    18901 cttagaaaaa gctaagtcaa aagaggaaaa taaatcgagt acaacaaaat taaattacat
    18961 tggagataaa gtaataagag gatattcaga aaaagaacct agttattcta aaactcttga
    19021 tgtttgggaa actcataaag gtgtagatat tagttgtact aaaggcaaag aagtaaaatc
    19081 tctattaaac ggaatagtag tagatgtatt taatgatgaa gaatatgggc aatcagtcaa
    19141 aataaaaagt gacaataaca ttgtagtagt atattcaaat ctagataaaa atgttagtgt
    19201 taagaaagaa cagaaggtaa cagaaggaca atctctaggt actgtaggta gtacttctca
    19261 aatagaaagt gaagaaggta tacatgttca tttagaggcg tatagtggag aaaaatctat
    19321 agacccaatg agtctaatta agtaaaagta taacaagttt aatcatattt ggttaagctt
    19381 gttatatttt ttggtgtttt tacatatata tcattaaagc tattatgtga ggggggtaat
    19441 ctttgagatc tcatatagag gaaagggcca tagtggtagc aaaatatata cttgaaaaaa
    19501 acactacagt aagacaaacc gccaagacat ttggagtaag taaaagtaca attcataagg
    19561 atgttacaga aagattgaag gaaataaatc catcccttgc caaagaagtt aaaaatgtgc
    19621 tggacaaaaa taaatcagag agacatatta gagggggatt agcaacgaaa ttaaaatatg
    19681 agaaggaaca taaaaaaatg taggttaaaa acctactttt tttattgaat taaattataa
    19741 aaagaaatat attaagtaat tataaatagc aaaataataa tactctcaaa agatttattt
    19801 tctcttgatt aaagcgagat ttttgtatat gctttattat aggagtatta aaataggctt
    19861 ataatataat ctaatattat aaataaagga gttgaaaaaa tggctggagc tgatataggc
    19921 atagatttag gtactgcaaa tgtgcttgtt tatgttagtg gtaagggaat cgttttagaa
    19981 gaaccatctg ttgtggcgat agacaaaaga acagattctg ttttagctgt gggagaagaa
    20041 gctaaaaaga tgatagggag aacaccaggt aatatagtcg ctataagacc tttaagagat
    20101 ggtgtaattt cagattatga tgtaactgag aagatgttaa aatcttttat agataagata
    20161 gttgataaaa agggatttgg aagatttttt atgccaagaa ttatggtatg tgtaccaaca
    20221 ggtgtcacag aagtggaaaa aagagcagta gaagatgcta cgagacaagc tggagctaga
    20281 gaagtatata tcatagaaga accaatagca gctgccatag gagctggtgt agacatatca
    20341 cagcctaatg gtaatatgat tatagatatt ggtggaggta ctgtagatat agctgtaata
    20401 tctctaggag gagctgttgt aagtgaatct ataaaggttg gtggagatag atttgatgat
    20461 gctatagtta aatatatgaa aaaacaacac aatcttctta taggagaaag aacagcagag
    20521 aaaatcaagt ttgaaatagg ttctgcattt aagagagaag aagaaaaata tatgaagata
    20581 acaggaagaa atttaattac aggacttcct agttctataa ctataaattc aacagaaatg
    20641 ttggaagcac ttagagaatg tgttgagcaa atagtagttg ctactcatgc tgttttggaa
    20701 aaaacgcctc ctgagttagc agcagatata ggagatgtcg gtataataat gactggagga
    20761 ggttcattat tatatggatt agataaaata atagaacaga ggacaggaat aactgttaca
    20821 atagcagatg aaccattatc ttgtgttgca aaaggtacag gaatagcttt aggttcaata
    20881 gacttacttg aaactggtgg gtctttcaaa agaaaataat taggagagtt tagaatgtta
    20941 aatatagatg aaataaaaaa attaatacca catagatatc catttttatt agtagacaag
    21001 attacagagc tagaagttgg gaaaagagct gttggtataa agaatgtaac agttaatgaa
    21061 ccatttttcc aaggtcactt tccagaatat cctttgatgc caggagtact aatagtagaa
    21121 gctctagcac aagtatgtgg agtggcaatg atgtctgtag aggaaaacaa aggaaaacta
    21181 ggtgtatttg caggtataga taaagttaga atcaagagag aagtaagacc aggagataca
    21241 ttaactatgg aaattgaaat gacaactctt agaaaaaata tagctaaggc agatgctaag
    21301 gcatatgtag gtgaagaact tgtctgtaaa ggtgaattaa tgtttgcttt agtagaaaaa
    21361 taaaaacttg aaatataaaa gtaaaaaggt agataatttg gagtatttaa tcagatactc
    21421 taaaatatct acctttttat ataaagaatt ttatcattta gtttatattt agattaggtg
    21481 gatactaata aagccaaggc tattgtttca gctaaatcta atataaagct aaggcgtata
    21541 ttattaaatg aaagtttatt attttcatca attttatcta caattcctac tatagaataa
    21601 tttcctattt gaggtagttt tttaccaaca ccttttccgg gcaggatagg tccttctcta
    21661 atctgtatat tacctatgtt actctgcgac cccaagcaag catctatagc caagaagtta
    21721 ccttgtatat gtgtattttt tatagtatct aaagactcat atatatttaa ggcgtgaata
    21781 gggttatcta gtgtaccgta aacggggtat ttaaagttac tgttcttaag tattgttcca
    21841 actaaagggc ctaaagtatc acctatagcc ctgtctgttc ctatgcaaac aacaatcgta
    21901 ttttcattaa ttatagtttt tagaactgaa cttagcatct gtataacatc atcatcgctg
    21961 tagtttactt tagctaaata caataggaac acccccttca aaaaaatata tgaataaaaa
    22021 gcattaaaaa gacctaactt taaatttcag atagatagaa aattttattt gtcttacaaa
    22081 aaaaggaata gaaaaaatat gactaaaaat attgacaaaa ttttaaaaaa atagtaagct
    22141 agtaaagtaa aacaaaactt aaatcttgat taccttatca agagaggctg agggataggc
    22201 cctgtgaagc ccagcaacca cccaaatggg aaaaggtgct aattcctaca agacaaaagt
    22261 cttgaaagat gaggtcagtt aattagtatg taattacgat tattaacctc ttcttataaa
    22321 ggagaggttt ttttattttg agtaaatttc taaaattaaa aataaggtaa aacctataat
    22381 aaaaattaag aataaataag ggggaataaa aatggcaaga catttattta cgtcagaatc
    22441 agttacagaa ggacatcctg ataagatatg tgaccaaata tcagattcaa tattagatgc
    22501 attattagaa aaagacccac aatctagagt agcttgtgaa actacagtta ctactggttt
    22561 agttttagta gcaggagaaa taagtacatc tgcttatgta gacattccta aattagtaag
    22621 agaaacagta agagaaattg gatatacaag agcaaaatat ggatttgatt gtgatacttg
    22681 cgcagttata acttctattg atgaacaatc tggagatata gctatgggag ttgatgaagg
    22741 tctagaaagt aagactggag aagagataga agaagaaata gaaaaagttg gagctggaga
    22801 ccaaggtata atgtttggat ttgcatgtaa tgagactcca gaattaatgc cacttccgat
    22861 atctttggca cataaattat caagaaggct tacagaagtt agaaaaacag gtttagttga
    22921 ttatttaaga ccagatggaa aaactcaagt tactgttgaa tatgaaggaa gtaaagctgt
    22981 aagagtacat acagttctta tatcagctca acattgtgaa acagtatcaa atgataaaat
    23041 aagagaagat ttaattaatc atgttattaa ggaagttata ccagcagaat tacttgatga
    23101 agagactaaa atttatataa atccaacagg aagattcgtt ataggaggac cacaaggaga
    23161 tacaggtctt acaggaagaa aaataataat agatacttat ggtggatatt ctagacatgg
    23221 tggaggagct ttctcaggaa aagaccctac aaaagttgat agatctgctg cttatgcagc
    23281 tagatatgtt gcaaaaaata ttgttgcggc tggtcttgca gacaaatgtg agatagaact
    23341 tgcatatgct ataggtatag ctagaccatt atctatattt atagatactt ttgggacagg
    23401 caaggtttca gaagaaaaac ttgttgaatt agtaaataaa cactttgatt taagaccggg
    23461 agcgataata agagacttag atttaagaaa gcctctttat aaaaaggttg ctgcttatgg
    23521 tcactttggt agaactgata tagatttacc ttgggaaaga actgacaagg ttgagcagtt
    23581 aagaaaagat gctttaggtg aataattttt aactaaaaag ctgttagaat gtaattttac
    23641 gattactttc taacagtttt tttattatga gttaaatatt tttaataaat gttaatttat
    23701 catcatataa tgaataaaca gtatttaatc tggtcaatac attttatata atactctact
    23761 aaatttatac atattatggg atatatgtta aaggatggtt aagaatgtgt taactaatgt
    23821 taaataatta aaaatatatt gaaatatcac aataatgagt ctaatataat cttaataaac
    23881 ttacacttta aaaataattt taattggggg ggagtagtgt atgtcaggca aagtaaatat
    23941 taaaacggtt ataagttttg ctggagctta tgttgctact gtaataggtt ctggatttgc
    24001 aactggtcaa gaaatactgc aattttttac gttttatgga tatgcgggta ttataggtgg
    24061 aataatctct atggtactat tttcatggtt tggagcagaa gttatagata agggaagaga
    24121 attgaaactt aaggagccaa taaaaattta tcaagtatat tgtggaaaat atcttggaac
    24181 attttttgaa tggtttggtc cattgttttt atttggaaca ttagtaataa tgattgcagg
    24241 agcaggagct acactatcag agtactatgg attaaatcca tatgtaggta ggattggtat
    24301 ggcaatcgtt tccctaataa ctgtttcatt aggtttgaca aggctttcta aaatactagg
    24361 taatatagga cctataataa taatatttac acttttagta ggagcaatta gtttatttag
    24421 caatattgat gctttatcaa atgctggaaa tatggttgat agtttaaata ttaaaactgc
    24481 tacatcaaat ggatatttct cgggagtact ttatacttgt tacaatgtaa taatagtaat
    24541 aacattcttg acaggaatgg gagcttctgc agtaaataag aaagatgctg tatggggtgg
    24601 tatagtaggt ggagtagcac ttatggcagc agctataatg atgaatttgg cattactttc
    24661 aaacatagga aatatataca caaaagagat accagcactt tacttagctg ataagatatc
    24721 tccaataata ggtattttat tctcagtagt acttttacta ggaatataca ctacagctgt
    24781 accattgtta tggtcagtaa ctaaccgatt tgtagaagat gaccacccta aatttaaaat
    24841 tataacaata gtggtaagta tattagcttg tataggaggt ttactgccat ttgataagtt
    24901 agtaggtaca ctatatccat atacaggtta catgggaatt ttaattttac tatgtatgct
    24961 ttatagaaga attactaaaa ctgaggggta caaggagaat aaatctgaaa taagttagta
    25021 ctgtaatata cttatggaat ttaatttata ctctaaatat agagtaatta aaataaaata
    25081 gctatttaaa tatggtacct gtatttcatg gtaccatatt ttatggatgc agattttttt
    25141 tgtttctgat aaaatgtata atagttggaa attacgttaa gtataaaaat ataaaacttt
    25201 tctacgatta tcatagtttt aatatataaa attatactaa catttaaatg gagcgattat
    25261 tagtattttt aggagataaa aatggaaaaa ttagaaggaa tgataagtga aatagtcttt
    25321 aaaaacgaag ataatggtta tacaatagct cacctggtaa atgaaaatga tgaaattgtg
    25381 gttgtaggat gtatgcctac tttggcaatt ggagaaagca tagaagttga aggaaagtgg
    25441 gtaaatcata agatttatgg gactcaattt gaagtgaata gttttatgcc agtaacgcca
    25501 tcatccttag aaggaattta tgtttactta tcttctggaa tgatacatgg tattggtgaa
    25561 aaaatggcaa aaagaataat tgataagttt ggtgtagata cgttagaggt gatacaaaat
    25621 tcaccagaaa aattacaaga agtagaaggt atagggagta aaaaagtaaa acaaatagta
    25681 aaaagttatg aagaagacag agaattgaga aatataataa tacagctatc tccttttgga
    25741 ataacaccaa attactgcct aaaaatatat aaaaaatata aaagcagtgc aatagaagtt
    25801 ataaataaaa acccatacca acttgctgaa gatataagag gaattggatt taaagtagct
    25861 gatagtatag caagtaaaat tggtatagat aaaaactcta aagatagaat ttgtcaggga
    25921 atcttataca ctttaaataa atctttaagt aatgggcata catatttacc agagcatgtt
    25981 ctaatacaag attcggaaaa attattggag ctaaatggag aaataataaa agagtgtgta
    26041 atgatgctag tttataatca aaaaatacat atagagaaag taaacaatga aaatcttata
    26101 taccttatgc catactattt agctgaaaat ggagtatgta gtcaaatagt aaaattatca
    26161 cagtatgaat ttgaagactt aaaaatagat atagataacg agattaatgt tttagaagaa
    26221 gataagaaaa ttaagttagc agaaaaacaa attttagcag tcaaagaatc tgttaatagt
    26281 ggagtattaa ttataactgg tggaccagga actggtaaaa caactaccat taatgctatc
    26341 atagatatat ttgaaaataa tggtaaaagt gtgactttgg cagctccaac gggaagagca
    26401 gcaaagagaa tgagtgaaac ttctaataaa gaagcaaaaa ctatacatag gttgctagaa
    26461 atgggatttt caacagatga tgatttaact ttttttaagg atgaagaaga cccaataaat
    26521 tcagatgtaa taattgttga tgaggtatca atggtagaca ttatcttaat gtacaattta
    26581 cttagagcta taaagttagg aacaagagta attttagttg gagatagtga ccaattacct
    26641 tctgtaggtg ctggaaatgt acttaaggat atgattaatt ctaatattat aaatgtagtt
    26701 aaattaaatg aaatatttag acaagcgcaa gaaagtatga taattgtaaa tgcccataag
    26761 ataaacaatg gagaaccact ttatctaaat acaaaaggta aagatttctt ttttataaga
    26821 aaatcaacta atgaagaaat tttaaatgaa ataataggat tggttaatga aagattacct
    26881 aaattttata aagttgataa attaaaagat atacaagttt tatcttcaat gagaaaaggt
    26941 gaattgggag ttactaatct caatatagag ttacagaagt atcttaacaa aaaagaaaaa
    27001 tttaaagttg aagaaagttt ttctaaaaga ttatttagag ttggcgataa ggtaatgcaa
    27061 gtaaaaaata attatacaaa aaaatgggaa acagaagacc aaaaagaaag tggagaaggt
    27121 atctataatg gagatatagg atatgtttat cacatagata aagataagaa aactatttat
    27181 atattatttg accagactaa aattgtatca tacctatatg atgaattaga tgaaattgac
    27241 catagttttt gtacaacaat acataaaagc cagggaagtg aatttccagt tgtagtattg
    27301 ccaatagcgt gggctcctcc tatgttactt agccgtaatt tattatatac agcagtaaca
    27361 agagcaaaaa aattagttgt attagttgga gatgtgaaat atcttgaata tatgataaaa
    27421 aataatagag ttaatcaaag gtattcaaat ttaggatata agctaaataa atttaaacaa
    27481 gaagggttgt tgatagaata aatatgaaaa tatgcaatga taattttatt aagaatttta
    27541 aaaatatgat taataaatgt ttggatttta tatatcctga gaatataagt tgcataattt
    27601 gtgataaatc cataaagaaa acaaatactt attcaatatg taaaagttgt tttaaagaaa
    27661 tgaattttat acaagatggt tgcatgaagt gtggaaaacc aataatacgt cattcaattg
    27721 aaaaagaatt tattgaagag tgtagttatt gttttaataa agacttttat tttgataaat
    27781 caatatcttg tattgaatat aatgatgtga caaaaaagat ggtgttaggg ctgaagtata
    27841 accaaaaaac ctttatggct aagtatatag ctcaaataat gaaagaaaaa ttatatttag
    27901 aaaacataaa atttgattat atattatttg ttccacttca taaaaaaagg ctaaataaaa
    27961 gaggttttaa tcaggcacaa aaaatagcat ttaatttaag taaaatagta aatattccat
    28021 tattagattg cataagtaga aaaaaatata caagaatgct atataaattg aataagaaag
    28081 aacgaaaaga agaattaaaa aatgtatttg ttgttaaaga aaatgttaaa ttaataaata
    28141 ataaaaatat acttttaata gatgacatat ttactactgg tctaacaaca aacgaaatct
    28201 ctaaactttt aaagttatca ggtgctaata aggtttttgt attgactcta cttacaaaag
    28261 caaatgataa ttatattatg gaataatctt atatattgac aattttagtt taaaatatta
    28321 aaatgaataa gtgatattta ggtctgtggt tgaaagtcca agccagtcgc aggcaaaggg
    28381 atccacgtaa gttaacacta aaaattgggt taatgatcat ggtgcggctt agaagtaaga
    28441 cctaccgata ataaaatcga gagagagtag tagtgcggcg aacccaagcg aaccctccag
    28501 taggcgagtg tggggtcaaa aaccaggtca gctaaatatc atattaaaag agagctagca
    28561 tacctttatg tatagctctt ttttatatat aataaattta ggttgagtca taaagaggtg
    28621 atatgtttga ataaaagaca agaaaattta ttaacaacat tgctattaaa agaagagttt
    28681 ataaatgtta ataagattgc caatgatttt gagtgttcag aaaggacaat aaggaatgat
    28741 tgcaaatata ttgatgaatg gttatctact ttttgtaatg cttatatcaa aagaaaacct
    28801 aatattggaa ttaaatttag tggagatgga acagacaaaa tactggtaaa tcagaagttg
    28861 cgaggtgaag ttaaaagagt aaatagtgag cttcataagc aagttgagat attaaattta
    28921 ctactttgta ataataaaaa agttacttta aatgatttat ctaataagtt gtacataaat
    28981 aaaaatattg tcagagaaga aataagtaaa ttatcagtag cattaaataa ttataattta
    29041 aatgtctcga ctaaaaaagg cagtggtata tatattgaag gggatgagaa agacataaga
    29101 ataatgttag tatcattctt atttaaatac atagataaat acagattaaa catagatgaa
    29161 atagagtact tccatatagt agatataata attgtaaaaa acataatgct tactatagag
    29221 gaggatatgg atataagact tacagatata tcattcaagc aattgatgct atttttgctt
    29281 ataaatataa tacgaataag gctgggaaat tctttaaaag tatcaaatac taagaaagag
    29341 cttaagctaa aaatgcttat attggatata gaagatgaat tgaaatctaa tttatccata
    29401 gtattaaatt atgaagaaaa attgtttata gaatctttaa tattgggtat gaacaaacaa
    29461 ataaatagta ataatattaa gaaatcttta tatctaaatg aagaattagc aagttataca
    29521 aaaaaaatta taaatttagt atcagaagaa tcaggaataa attttaataa tgatatatta
    29581 ctttatgaac aattaatatg tcatttgaat gttacaatgc atcaaatgaa aagcaatgtt
    29641 tacttagaaa atccactttt agataacata aaaactaaat tttgtttttt atttacagta
    29701 atatcaagtt caatagaaat tgaattaaaa ggaaaacaaa taacggaaga tgaaattggt
    29761 tatcttacac ttcactttca aacctctcta gaaagaaaat acagcaaaag ggaatcaaat
    29821 aaaaaggcaa gtattgtatg tccatttagt tttggagtaa gtatgctatt aaaagtaaag
    29881 atagaaaaga gatttgataa cataaaaatt attgaaacat taagagagga agatttaaaa
    29941 agagataact ttaataagac tatagatttt ataattgcat ttcaagagta tgaaaatatc
    30001 caaaaaccaa tttttataac aacaccatta tttactgatg aggatgagaa taaacttaaa
    30061 gagtttacaa acaaaataaa agaaaaagac acctcatata aacttatgaa cagattaatg
    30121 atgtctgatt atttaataag agagttagaa catgatgata tttatgaagc tataacatat
    30181 ttaactaatt tattaattga aaaacattat gcagaaaaag agtatttaca atctattata
    30241 acaagagaaa agtcatatcc aaccaatgtt ggaaaaggaa tattattccc tcatggagac
    30301 atgaaatata taaaacaatc tgttttatgt tttgcaaggt taaaaacacc aataaaaatt
    30361 agaaatggaa aggatataaa gattatactt ttattagcat ataaaaaaga tgatgataga
    30421 aaagtattta gagaattatt taaagaaata tctaatttaa cagaggatga aaatatgcta
    30481 gatattctaa gtaaatgtga cattgaaaag gtaaaagata ttcttatata aaattcataa
    30541 tgaactatgg ataagcacaa aattttccat gtgatggaaa aagttgtgca tgtttttttg
    30601 tttttataag atattatatg tttgtaaggt ataaataatc taaaagtaga gaagcaattt
    30661 aggaggaaaa aatggaagaa atagttttaa agattataat tcatgctgga aatgcaaaat
    30721 ctatgcttta tgaagcactt gactatgcaa aggaaaacga ttttaaaaaa gcagatgaat
    30781 taattgaaaa tgcaaatgaa gaaattttaa aagcacataa agtacaaact gaacttatac
    30841 aaaaggaagc tgggggagat aaatcagata tatctatttt attgattcac tctcaagacc
    30901 atttaatgac ttgtatgagt gagagaaacc ttataaaaga aatgattatg ttaagaaaag
    30961 aaattcaaaa attaaaataa aaaaattaag ggggatttaa aagaatgaaa agaaaagtat
    31021 atttattttg tagctttggt atgtcaacaa gtttacttgc agataaaatg cagaaggtag
    31081 cagatgaaca caatttacca atagaagtag aggcatttcc gatagcagaa attgacaaaa
    31141 tagttgaaga aaaaaatcca gattgtatat tattaggacc acaagttaaa tacatgctaa
    31201 aggagttaaa accaaagttt gaagctcaag gaaaacttat agatataatc aatgaagttg
    31261 attatggaac tatgaatggg gaaaaagtat taaaacttgc tataaagcta ataaaatcta
    31321 aacaagcgta gaattatagt aaaaaataat aggaaatgag ggtggataga tgaatagatt
    31381 ggaaagaata cttatgccat tggctgaaaa aataggtaaa aataaattat taattgcaat
    31441 tagagatggt tttttaatat catcaccatt attaataata ggttcattat ttttattagt
    31501 agcaaatttt cctataaaag gatggaatga atttgtaggt caaatttttg gtccagattg
    31561 ggctgtaaaa ttgcaacaac caactgtagc aacatttgaa gtaatgactt tacttgcagt
    31621 tttaggaatt ggatattctt atgcaaagca aatagatgta gatccaatag catcagctgc
    31681 agttgcaata gttgcctttt ttatagtaac accgtttgta ataccatata caccagaagg
    31741 aacagaatca gtctacatgg taacaggtat accactaggt tggatgggct ctaagggaat
    31801 gtttgtaggt atgataacag caataacctc tgtaaaatta tttgctgcag ttgtaaaaaa
    31861 aggatggaca ttgaaaatgc cagatggagt tcctccaacc gtatcaaaat catttgcagc
    31921 attaatacca agtgcaatag ttatggtagt tttcttttta gttaagatag cttttgaagc
    31981 tacaccatat ggaagtatac atgaatttat atttaagttt ttacaaatgc cattattaaa
    32041 attaggaaat agtttaggtg ctatggcaat cgcttatata ttcttacatt tattctggtt
    32101 ctttggaata aatggaagta gtgttgttgg ggctgtgtat aatccaatat taaaaattct
    32161 atcagctgaa aacttagctg cttttcaggc tggttcaaaa ataccaaaca taataacagg
    32221 tcaattccaa gatatgtttg cgacatttgg tggagcaggt agtacactat cattagtcat
    32281 agctatgtta ttaatatgta aaagtaaacg tataaagtca atgggaaaac tatcaatttt
    32341 accaggaata tttggtataa atgagccatt gatatttggt ctaccaataa tgcttaaccc
    32401 aatactattg ataccatttg caatagttcc aacaataaat ataataatag cttacttctg
    32461 tatgtcagca ggattagtgc ctcttacaaa tggagttcag ttaccgtgga caactccaat
    32521 tatattctct ggttttttaa caacaggatg gcaaggtgca gtcttacaat tagtgcttct
    32581 tatactagga atatttatgt atataccatt tataaaaatg ctagataagc aatacttgag
    32641 agaagaaaat gaaactgttg aagaggaaga tgatgatata tcttttgatg atttagtatt
    32701 ataggaggaa gattatgaag aaaatagtta tgatattgga tcaaatacaa gctggagctg
    32761 gaggaaaaga gaaaagtaat atacctcctg ctggaaaatc aagcccatta ggaccaggtg
    32821 taatgatgga gcaattttta aatgaatcta aggtaatagc taccttattt tgtggggatg
    32881 aattttttgt aaataatgaa aaagaagtaa cgagtaagat gatagctatg gtaaaaaaat
    32941 taaaccctga tgtagtaatc tgtggaccaa gctttaatta cgaaaacttt tctaagatgt
    33001 cagcaatact gtctaaaaat ataaatgata aaacagatat accagctttt gcagctatgt
    33061 cagaagaaaa tatagatgtg ataaacgaat ataaaaatga catatgtata gttaagactc
    33121 ccaaaaaagg tggaattggt cttaatgatt cattaaataa catatgtaaa ttggcaaaag
    33181 caatagcgaa taaagaagat ataactttga tgaaagaaga attttgttat taataagagt
    33241 attaattatt agcaagttta aatattatac tatttataat aagcatacat tagtaaaatc
    33301 tatataattt aaggagggga attttaacat gtggggaatg atagcgacat ggagaatggc
    33361 cctagaagga ataactgagg catcagaaca tttagaaaaa ggcatggaag caggtgatgc
    33421 tgtagagctt gctgtaagaa gagttgaaga ctatccattc tataaatcgg ttggatatgg
    33481 tggacttcca aatgaaaatt gtgaggtaga acttgacgct gcatttatgg atggtaacac
    33541 attagatatt ggcgcagttg ctggtataag agattattct aatcctgtca gcatagctag
    33601 gaagttaagt tatgagaagg taaataattt tttagttgga ataggtgctg aagattatgc
    33661 tcataaaaat ggatttgaaa gaaaaaatat gttgactgat agagcgaagt tacattataa
    33721 aaagagaaaa aaagagactt tagacaaagg attaagccca tatgctggtc atgatactgt
    33781 tggtatgata tctttagaca aaactggaaa aatgtgtgca gctacatcaa caagtggatt
    33841 gtttatgaag aaaagaggta gaataggaga ttctgcacta tctggttcag gattctatgt
    33901 tgatagtagt ataggaggag ctacagctac tggtttggga gaagatttaa tgaagggatg
    33961 tatatcttat gagatagtta ggcttatgaa agaaggaaag catccacaag aagcatgtga
    34021 tattgcagta aatgaacttg ataaacagct tatcaaaaga agaggaaaag ctggtgattt
    34081 atcattagtt gccatgaata ataaaggtga atggggagta gctacaaata tagttgattt
    34141 cactttttca gtagtaacta aagaagaatc tcctgctgta tatatttcaa atagagtaga
    34201 tggaaagact atacataagg ttatatcaaa tgagtggatg gaagcatatg aggctagaat
    34261 aaaagcaccg atagaagtaa gtgagtaaag tagtgttaca taattaaaat agagttttat
    34321 aataaggaga tttttatgaa tatcataagt aataaaatag atgagttaaa agaagattta
    34381 ttaagtgata ttatagatat tgtaaaaata cctagtgtca aaggggagtc agaaaatggc
    34441 ttcccttttg gcgaaaaagt aggggaggca cttaataaag cattagaaat atcaaaaaaa
    34501 ttgggattta aggttagaaa cttggataat tatattggtt atgcagagca tggagatagt
    34561 gatgattatg tttgtgtaat tggacatgta gatgttgtac atgaaggaga tggttggaag
    34621 catcagcctt ataagggaga agaaactaat ggaagaattt atggacgagg agtactagac
    34681 aataaaggac ctataatgtc tgccttatat ggattatatg ctattaaaga attaaactta
    34741 aaattagata agagagttag aataatattt ggtacaaatg aagaaagtgg atttgaagat
    34801 ataccatatt atttagaaaa agaaaaaaca cctattatgg gatttacacc agattgtaaa
    34861 tatcctgttg tatatggtga aaaaggcatg gcaaagatta gaataaaaag taaaatcaat
    34921 tatgaagaag atgtatacct aggttttata gaaaatatgt ctgaaaatgt gcttgttaca
    34981 tataaagagc tgaatataga aaatagtaat actatattag atataaaggt aaaatacgat
    35041 tttagttata aattgaaaga tgtattagat gaaataaaag ctagttttcc aaatagtatc
    35101 gatatagagg taatttctaa ttttaatcct gtatattttg ataaagagag taatcttgtt
    35161 aaaaagcttc agctagctta tgaaagggtt acatcattag atggaactcc cgtgacaact
    35221 aatggaggta cgtatgcaaa agtaatgcca aatatagttc cgtttggacc ttcatttcca
    35281 ggacaaaaag gaatagctca taatcctgat gaatacatgg atatagaaga tataatatta
    35341 aatgcaaaga tatttgcaaa tgcaatatat gaattagcaa aggagtagtt atgttagaaa
    35401 taataggaat gtcagtagaa gacgctaaaa ttatagaaga ttgtggtgca gatagaatag
    35461 agttagttag tgctttaact gaaggtggat tgacaccaag ttttggtctt atagaaagtg
    35521 ttgttaacag tgtaaagata cctgtgaacg taatgataag acatcatgcg aaaagttttg
    35581 tatacagtaa agaagatata agtataatgc aaaaagatat aggtgtggtt aaagagattg
    35641 gtgctaatgg agttgtattt ggtgtattgg ataaaaacaa taatatagat gagaaaaatc
    35701 taaatgtttt attgaaatgt tgtgataatc ttgatgttac atttcataga gccatagatg
    35761 aatcaaatac aatagatagt gttaaaattt tgaaggatta tgataaaatt acgaatatat
    35821 taacatcagg agggaaagga agtatagttg ataacataca aatgataaag aatatgatgc
    35881 ttagttctaa tcacataaaa attcttttag gaggaggtct taattttaat aatatagaaa
    35941 agataaagga attaactaaa gcaagtaatt ttcattttgg tacagcgatt agaataaata
    36001 acagtccttt tgaagatata gatagacaaa agcttaaaca actcgtaaat ataatttcaa
    36061 gatagtatat gaatataaaa tacttagttt aaataaagag agtaagttaa ttataatttg
    36121 ggtatatgaa tgttaatagg tattaaatat gaaattattg ttgagtatgc tttataactt
    36181 ttaagtagtt ttaaatataa ataatgaaag aaaagataga ttatggaggt tttagagggt
    36241 ttatagttat taaaaaatta taaaggtata ttggcatata atacacataa tttcctaaaa
    36301 ttaccatctt atgacatgaa ttcacatatt aataaacaat taatggagat ttttgtggat
    36361 agaaatagga gtaaaaatag ctttaaataa acaaaaacaa gagttattaa cagttttatc
    36421 cacattatcc acaggtgttt gtaataatat taatccacat aagtatcaat gtaactaaaa
    36481 atgataaata attctatcaa ttgaatagaa aaaatcataa aagtaaataa taaaaagagg
    36541 attatgagag ttcgtgtaga atatattatt aaagtataaa ttttcttata ctgacataat
    36601 tgaagggaga tgtatttatg aacataatta tatctggaaa acaaatcgaa ttaactgatg
    36661 caataaaaaa taaaatcgaa actaaactaa gtaagttaga taattacatt catccagaca
    36721 ctgatgtaaa agttacagta agtgcgagaa aagcaagaca aaaaatagaa gtaacaatag
    36781 ctactgtaaa tggtcctata attagagcag aagatatgca ggaaaattta tacacagcta
    36841 tagatgttgt atatgataaa ttaagtaaac aattaaaaaa atataaaaag agattacaag
    36901 ataaacataa agacaacaag agtataagat tccaagattc agagataaat ctagctgatg
    36961 aacaagagga ttatggggat gaaaatcaag aattagtaat tcaaagacgt aagaaattta
    37021 gtgttaagcc aatgagtgaa gaagaagctg tattacagat ggaattaata ggacatgatt
    37081 tttatatgtt caagaacata gattcagatg aaatagcagt agtttataag cgtaataatg
    37141 gtggatatgg tataatagaa catgaataaa gcaatttaga tttaatcata ttagctatcg
    37201 ataaataaat tatcgatagc tttttaaatt aatattaaaa gtatagtttt tatggtaaaa
    37261 tgaataatag tacaataaag aacgaggaga gatgtaaaat atgagcttta tggataattt
    37321 attcaacatg gcagataaaa aagaattaaa aaagttcaat aaaactgttg atataataga
    37381 ttcattagaa cctaaatttg aatctatggc agactcggaa cttaaaaata tgacaaatat
    37441 atttaaagaa agattagcaa atggtgaaag tatagatgat atacttccag aagcttttgc
    37501 agtagttaga gaagtttcta agagagtgtt aggacttaga cactacagag ttcaaatgat
    37561 tggaggtata gtactacatc aaggaagaat agcagaaatg aaaacaggtg aaggtaaaac
    37621 tttggttgca actgctcctg tttatttgaa tgcgcttact ggaaaaggtg tacatgttgt
    37681 aacagtaaat gattaccttg caaaacgtga tagagaccaa atggcaaaaa tctatgagtt
    37741 tttaggaatg agtgtaggcg ttattataca cggtcaaaat ccaaaagtta gaaaagaaca
    37801 atatgattgt gatataactt atggtacaaa taatgaatat ggatttgact atctaaagga
    37861 caatatggta atacacaaag agcaaagagt tcaaagagga ttaaattatg ctatagtgga
    37921 tgaggttgac tctatactaa tagatgaggc tagaacacca cttatcatat ctggacctgg
    37981 agacaaatca actcacttat attcagatgc aaacacattt gttttaacct taaaaccaga
    38041 tgattatgaa ttagaagaaa aagataaggc tgtatctcta acagcatcgg gtatacaaaa
    38101 agcagaagtg tattttaatg ttgataatat aacagatata tctcatacag aattatacca
    38161 tcatataaat caagctttaa gagcacatgt aataatgaag aaagatgttg attatgttgc
    38221 taaagatgga gaaatagtaa tagtagatga gtttacaggt agacttatgt ttggtagaag
    38281 atattcagaa ggtttacatc aagcaataga ggctaaagaa ggtcttaaaa tacaaagaga
    38341 atctaaaaca ctagctactg taacattcca aaactacttt agaatgtata aaaaactttc
    38401 tggtatgact ggtacagcaa aaacagaaga agaagagttt aaagcaattt ataaaatgga
    38461 cgttttccaa gtacctacca ataagcttat ggtaagagaa gatttaccag attctgtata
    38521 caaaagtgaa ataggtaaat ttaatgctgt agcacaagaa ataattgaaa gacataaagt
    38581 taatcagcca atacttgtag gtacagtatc gatagaaaaa tcagaattat tatcacaaat
    38641 attaaagaaa aaaggcatta aacatgaagt attaaatgct aagcatcatg ataaagaggc
    38701 agagataata gcacaggctg gtagattagg cgctgttaca atagctacaa atatggctgg
    38761 ccgtggtaca gatatagttt taggtggaaa cccagatttc ttaactaaga gagaaatgag
    38821 aagaaatgga tttaaagagg aaatagtaaa tagggtagat actccaatag aaggtatacc
    38881 tgtaaaaggt aatgaaattc tatttgaagc tagagaagag tatgaaaaac tatttgaaaa
    38941 gtttaagcaa caaacacaag aagaacaaaa acaagttgta gaagcaggtg gacttgctat
    39001 aataggtaca gaaagacacg aatctcgaag aatagataac cagttgagag gtcgtgctgg
    39061 tcgtcaaggt gacccaggga gttcaagatt ctatataggt cttgatgatg accttatgag
    39121 attgtttggt agtgatagaa tatctggtat tgtagataaa ataggtcttg aagaagacat
    39181 gccgatagaa catagaatat tatctaagtc tattgaagga gcacaaaaga aagtcgaagg
    39241 taaaaacttt ggaataagaa agcatgtact tcaatatgat gatgttatga ataaacaaag
    39301 agaaataata tatgcagaga gaaaacgtgt attagaaggt gaagatttac aagaacaaat
    39361 acaatcaatg actcattcta taatagaaga agcagttact ctttatacac aagataaagg
    39421 atttgatgaa gaaggattca aagaacatat gtataatctg ttcttgccaa aaggtagcat
    39481 agaaatacca gaaatagaaa aacttaatcc agttgaaata acagaaaaag tttatgaaat
    39541 agctatgaag atatatactt caaaagaaga acaagttggc tatgagagaa tgagagaagt
    39601 tgagagagta atcttacttc aagctgttga taaccattgg atagaccata tagatgctat
    39661 ggaccaatta cgccaaggta ttggtcttcg tgctgtaggt cagcaagacc cagttattgc
    39721 ttataaaatg gaaggttttg atatgtttga tgaaatgaat aaacatatca aagaagacac
    39781 tgtaagatat ttatttaata taacaataga aactccagtg gaaagaaaag cagttgtaga
    39841 tgttgaaaat ctatcttctc catcagatgg aacacttcca acaagtaaaa ctgttaaaaa
    39901 agatgaaaag gttggaagaa atgacttatg cccttgtgga agtggtaaaa aatataaaaa
    39961 ctgttgtgga agataatctc ggaggattaa atgttaaagt tacaagagta tagacatagt
    40021 atggagcaga tggcttcaaa tttagaagaa ttgagggttt ctctttgaca tagcttcatt
    40081 gatgaaaaat atacaaatta atgaagaaaa gatgaatcaa caagactttt ggaatgataa
    40141 tgaagtcgct caaagagtac ttcaagaaaa taaatcttta aaagagacat tagaagaata
    40201 tgaaagctta aaaagcttat tagaagatat agaagtatta attgaaatag gtttagaaga
    40261 agatgatgat tctgtagaaa gagatataga aaagtccata gaatcaatgg aagaaaaatt
    40321 atctgaaatg aaaataaaga ctcttctaaa tggagagtat gataaaaata atgctatatt
    40381 atctataaat gctggtactg gtggcttaga tgctcaagat tgggctcaaa tgcttttgag
    40441 aatgtatata agatggtcag aaagtaaggg ttataaagtt aagcttttag atataatatc
    40501 agaccctgaa gcagggataa agacagctac aattcttgta gaaggaacaa atgcttatgg
    40561 gtatttaaag agtgaaaaag gagttcatag attagtgaga atatctccat ttgacccatc
    40621 agggaaaaga catacttcat ttgcatctat agatgtaaca ccagagttag atgaaaatat
    40681 agaagtagaa attaatccgt cagatttaaa gatagacaca tatagagctt ctggagctgg
    40741 agggcaacat gtaaatacta ctgattcagc agttagaata acacatatcc ctactggtgt
    40801 agtagttcag tgccaaaatg aaaggtctca gcatctaaat aaggacagag ctatgagact
    40861 tttaatggcg aaattgatag aattaaaaga gttagagcaa aaggaaaaaa tagaagatat
    40921 acaaggcaaa tactcacaaa taacttgggg tagtcaaatt aggtcatatg tttttcaacc
    40981 atataaattg gttaaggacc atagaacaaa tgctgagttt ggaaatgtag atagtgtaat
    41041 gaatggaaat atagacttgt ttattaatga atacttaaaa atgaataaaa tagtttaata
    41101 aatatgcact gtaattaaga tatatgtata agaaggttag tgcttaatat gcacttacag
    41161 cacttaggct gaggacgata accctcagcc ttcgttctgt tttgttatac ttatgaaaaa
    41221 ctaacattag gagtgaataa attggatata aatcaaatct taaaaaaaga gtttaatctt
    41281 agagatgaac aaataaataa tacattaaaa cttattgatg aaggaaatac aataccattt
    41341 atagctagat atagaaaaga aatgactggc gaaatgagtg atgttacact aagagaattt
    41401 tatgaaaaat taatgtattt gagaaatctt caaagtagaa aagatgatgt agttagacta
    41461 atagatgaac aagggaaatt aacagatgaa ataacacaaa atatagaaaa agcaaaaaca
    41521 ttacaagaag tagaagatat atatgctcca tataaacaaa agaaaagaac tagagcaaca
    41581 atagcaaaag aaaaaggatt agaaaattta gcattgtcaa tactagagaa taatttagat
    41641 aatatagaaa tagaggcaaa gaattatctt gatgaagaga aagaagttct ttctattgaa
    41701 gatgctctaa aaggtgctag agatataatt gcagaactag tctcagatga tgctaagatt
    41761 agaaagtata taagagaatt agctttaaga gaaggtatga tagttagcaa aagtgctact
    41821 gatgagaaat cggtttatga tatgtattat gattataacg aagcagtaaa aagtatggct
    41881 ccacatagag ttttggcaat aaacagagga gaaaaagaaa gcttcctaaa ggttaagtta
    41941 gaaataaata atgataaagt tttaaattac ataataaacg aatatgtaaa tgataaaaat
    42001 ttcaaaaata aagaagaaat cgtaagttca atagaagatt cttataaaag attaattttc
    42061 ccatcaatag aaagagaaat aagaaatcat ttaacagaaa tagctcaaga aagagctata
    42121 agtgtatttg gaaagaatgt taaaagttta ttgcttcaac caccagttaa agacaaagta
    42181 gttatgggat ttgaccctgc atttagaact ggatgtaaaa tagctgtagt agataaaaat
    42241 ggtaaactac tagattatac aacagtatat ccaacagacc ctcaaaatga tgtagaggga
    42301 gcaaagaaag ttttaaaagg attgattgaa aaatacgata tagatataat ttcaattgga
    42361 aatggtactg catctagaga atcagaaact tttgtatcag aaatgataaa agaaatagat
    42421 agcgaagtgc agtatgtgat agttagtgaa gcaggagcat ctgtttattc agcatctgaa
    42481 cttgcaaatg aggaacatcc agatataaat gtatcaataa gaggagctat atctatagct
    42541 agaagattac aagacccatt agcagagctt gtaaaaatag accctaaaag tattggtgtt
    42601 ggtcaatatc agcatgattt aaacaaaaag agattagaag aagtgctaga tggagttgtt
    42661 gaagattctg taaatagtgt tggagtagat ttaaataccg catcatactc cctactagaa
    42721 catgttgcag gaataagtaa agctatagca aaaaatataa tagcatatag agaagaaaat
    42781 ggagatttta catcaagagc acaattgaaa aaagtaaaaa gactaggacc tcaagcattt
    42841 actcaatgtg ctggatttat gagaatctta gagggtaaaa atccactaga taatacaggt
    42901 gtgcatcctg aaagttatga tatatgtaaa aaaatgattg agataattgg atattcttta
    42961 gatgatgtaa agaataagaa tataggtgaa atagatgaaa aaataaaaga aattggcttg
    43021 agggaattaa gtgaaaaact ggaagtagga caagttacgt taaaagatat catagctgaa
    43081 atcaaaaaac caggaagaga cccaagagaa gaaggtataa aacctatact tagaactgat
    43141 gtcttaaaaa ttgaagatat acaagagggt atgactttaa aaggtacaat aagaaatgtt
    43201 gtagactttg gtgcatttgt agatattgga ataaaaaatg acggattagt tcataaatca
    43261 gaaatgagta atagttttgt gaaagaccct atgagtattg ttacagtagg tgatatagta
    43321 gatgtaaaag tcattggaat tgacttaaac aaaaaaagag ttgccttatc aatgaaaaaa
    43381 tagataagtt tatgtatggt tatagtactt aaattctata tttgtaaatg agattactcg
    43441 agtgtataaa tgttaaaaat ttgtaaaagt atatagtaag aaaatatatt aaaataagaa
    43501 cgatagtctt gaaaatcagg aggaaaatga atgattttta taaaaaatgg taaaataaat
    43561 accataacaa atgggataat tcatggagat atacttatag atgaaggaaa aataatagaa
    43621 attggagaag atttgatagc tcctttagat gtagaggtaa tagatgctag taataaactt
    43681 gtgtttcctg gatttataga tgctcatact cacttaggtt tatgggaaga tggtataggg
    43741 tttgaaggag cagatggaaa tgaagagact gacccaataa caccacaatt aaatcctata
    43801 gatggaatta atccaatgga tagaactttt aaagaagctt ttgaaggtgg aataacttct
    43861 gtttgtacaa cccctggaag tgcaaatgtt atgggtggtc aatgtatagc tataaagaca
    43921 tgtggaaaaa gaattgataa aatggtaata aaaaatccag ttgcatctaa aattgctttt
    43981 ggagaaaatc caaagagctg ttatggtcag gatgataaat ctcctcaaac tagaatggct
    44041 atagctgctt tacttagaga aaacctaaaa aaagcagaag aatatttaga ggatattgat
    44101 atgtatgaga gtcatgatga tgaagactgt gaaaaacctg aatatgatat aaaaatggaa
    44161 agtttaatac cagttttaag aagagaaatt ccttttaagg cacatgctca tagagcagat
    44221 gatatgttta cagcaataag aattgcaaaa gaatttaatt taaagcttac attagaccat
    44281 tgtacagaag gtcatcttat tgtagatgaa ttagtggaag aagggtttcc tgtaatagta
    44341 gggccatctt tgtcagaaag gtctaaattt gagcttagaa atttgacatt taatacagca
    44401 ggaatacttt caaatgcagg tcttgatgta tgtataatga cagaccatcc agtaatacca
    44461 gttcaatatc ttccaatatg tgcaggtatt gcagtaaaac atggtatgaa agaagaaaaa
    44521 gcaatagaat caattacgat aaatccagct aagactttag gaatagaaga tagagtaggc
    44581 tctatagaag ttggtaaaga tgcagaccta gtaatttggg ataattctcc actagagatt
    44641 caaagtaatg tactttacac tataataaat ggcaaagtag tgtatgagaa aaaataactt
    44701 gacaattatt aaaaaattaa ctaatataag agtgtaagga aaattaaaaa atcaaagaag
    44761 atcttcgggg cagggtgaaa ttccctaccg gcggtatagc ccgcgaacta cttaggtggt
    44821 tgatttggtg agattccaaa gccgacagta aagtctggat gagagaagat atttatggaa
    44881 gataaataag tttattttag tttgtttaaa ctatatccat aaaaactcga agatagggtc
    44941 ttcgagtttt ttgtttttcc taaaaaatat aaacatattg attaggggga aaataattat
    45001 gcaaaacaca gcaaaaagag gcaatatgat ttcaacaaga actttagtag taatgtcaat
    45061 tttatctgca atatcttatt tattaatgtt tattcaagca ccaataccag gtatatttcc
    45121 agatttctta aaaattgact tatcagatat tccagcaata ttcggaggaa tgtctctagg
    45181 accattagtt ggatttggaa tagttgtagt aaaaaatgtg ttacaagcaa taacagcaac
    45241 aacaactgga ggaataggag aatttgcaaa tatattaatt ggtggttctt atgtaatgat
    45301 actttgttat tcatataaga gaagtggaga tttaaaaggt gtactgattg gttttgtatt
    45361 aggaacaata tctatgacta taattggttc attagtaaat tattttgtaa tgttgccact
    45421 ttatggtcaa cttatgggac tagatgctat aataggttta ggttcagcta taaatcctca
    45481 agttcatgat ttattcactt ttgtaatttg gatgatagct ccatttaatg tgctgaaggc
    45541 tgttataata tctttagtaa cattgccact ttataaaaaa atgggaaata taataaagaa
    45601 ataattagac aagaaaatat aaaattaaat gtattgaata gccataattt atttataact
    45661 tcagtcctat attgtgattg atatattaaa tatattatgg ctttattaat ttatcaaaaa
    45721 atgtatataa aataagaaat atttagacaa atttaaattt taaaataaag gaagaattaa
    45781 aacgattaac tattaaaata tgaaaaaggt atctacaata tacagagcga atttataata
    45841 aacaaaaaat aaagttatta ttaaaaaact ataaagacta ataatcaaac ttttaataat
    45901 aactaattta ataatgatag gggtgtatat tcatgcattt atctaaaaaa ataaaaaaat
    45961 tatttttaga tgataaaggg tattatttta atagtaattg ggaagatatt catattggta
    46021 tttatgatac aaaattagga gattctttaa agtatatcac taatgaatat attgaaaata
    46081 tggaaagggt aaaatacgat tatcgtgaat taaaaaatat agaaaatcaa actgatggta
    46141 tgtgtatttt agcaataagg cagaattaca aggcattaga gtatgtaaaa aatcaaaccg
    46201 aagaattatg tttagaggca ataaagtata attataaagc acttgaatat gtaaaagaac
    46261 aaacagaata cttgtgtctt gaagctataa aaaaagattg taatgcactt aagtatgtac
    46321 gaaataaaac agaagggctt attataaaag caataagtca ttcttccaat atagatgttg
    46381 taagtatact aaaggcttta gagactcaaa caagaaggat atgtttagaa gcaattaaaa
    46441 aagatggcag gtgtcttgca tacgttagag aacagagtga agaattatgt atagaggcca
    46501 ttaagcaaaa ttataaagca ttaaaatatg taaaaaatca aacggaaaaa atgtgtatag
    46561 aatccgtaag acaaaatggt atggcattac aatatgtaaa taaacaaact gataaaatat
    46621 gtatagaagc tgtcaaacaa gatggaagaa gtctacaatt tgtcaacaat aagacagaag
    46681 aaatatgtat aaatgctata agatatttaa ataaaaaata taatattaaa gatgtactaa
    46741 gttacataga taagtataca gaagatatat gtatagagat tgtaagacaa aatggaaaaa
    46801 tgcttatgta tataaaaaat caaacagaaa aaatgtgtat tgaagcagta aaagagaact
    46861 ataagtctct taagtatgta aaagagcaat ctgagagaat atgtaaagaa gcattgaagc
    46921 aaaaccataa agcaaaagag tatgtaaaaa ttgctattga tgattgtata taaggtgtag
    46981 atacagccat caatagtgaa agataaaaaa agataaagac aagtacttta taataatcta
    47041 ggcttatact ataattaatt aagcagtgat ataaattcac atgacgatta tatcaaaatg
    47101 gagatgaatt gatggcaaaa atatatttag aaaatgaaaa taaaactaga gaaataggat
    47161 ataaattagg taaactttta aaagaaggca gtgttatctg tttagtagga gatttaggag
    47221 ctggtaaaac tacaatgaca caaagcttgg cagattcatt agggatagaa gattatataa
    47281 caagtcctac ttttactata ataaatgaat atgaaggaaa aatacctttg tatcattttg
    47341 atgtttatag aataggtagt agtgatgaaa tgtatgatat tggttatgat gaatatgtaa
    47401 attcaaatgg aatctgtata atagaatggg ctaatctaat agaagatata cttccaaaag
    47461 aatatttgaa tatagaattg agatataaag atgaaggaag agaaatgata ttaactccaa
    47521 aaggagagtt ttataaagag atagttgagg agttgattaa ataatgaaaa tactaggtat
    47581 ggatacgtct tctatggcag caagtgtagc agttgttgaa gatgataact taatatgtga
    47641 gtttacagta aacaacaaaa aaactcattc acaaaagctt atgccaatga tagaaaatat
    47701 gttgagtatg agtgatttaa gtataaaaga tatggattta ttagctgtat gtataggtcc
    47761 aggttcgttt acaggactta gaataggtat ggctacagta aaagctatgg cccatgtaaa
    47821 taatatacca ataatagcag taaattcttt ggaatctcta gcaaataaca taaatttctg
    47881 tgatagaaag atatgttgta tattagatgc gcagaaaaat caagtttatt cagctaaata
    47941 caagtttgaa aatggagaga tgatagaatt agatggtgtt gatgttgtag agtttgatgc
    48001 tttagtagat gaaattgtat caactaatga agaatttata atagttggag aagctgtata
    48061 caaatataaa gacaagttag agaatataaa aaatataaaa ataccttcac cagctaataa
    48121 tgtatctaac gcaggaagct tatgctcttt agcattaaat aaatataata aaaatataga
    48181 tgtacatact tgttatacga taaatcctat gtatatcaga aaatctcaag ctgaagtaca
    48241 atatgatgaa aaaatgaaga ggctaaataa tggaagataa tacaaaacta atagtagatg
    48301 atataaaaat agaagaaatg actacagaag atatagatga agtttttgaa gtagaaaaaa
    48361 attgttttga agattattgg tcaaaagagt cttttagaaa agagttgtct aatgaagtag
    48421 caaggtatat agtagctaag ttaaatggaa aaattgtcgg atatgtggga atttggctta
    48481 tacttgatga agggcatata aataatgtgg ctgttcatag tgactataga gggaaaaaaa
    48541 taggggacaa gttgataaaa tgcatagttg atttatgtaa agataataat attgcatcta
    48601 tgacattaga agttagagca tcaaataaaa tagcacaaaa tttatataga aaatatggat
    48661 ttaaaatggg tggaataaga aaagaatact acagtgataa taaagaagat gcaattataa
    48721 tgtggaacca attaaaagag gtgtagagtt tatgagtgat ataataacat tagctataga
    48781 gagtagttgt gacgaaacag ctgcatcagt tttaaaaaat ggtagagaag tactttcaaa
    48841 cataatctct actcaaatcg agacacataa aaaatttggt ggtgtagttc cagaagtggc
    48901 ctcaagaaaa catgtggaaa atattgatat agttgttcaa gaagctttag acaaagcaaa
    48961 tataggtttt aatgatatag accatatcgc agttacatat ggacctgggc tagtaggtgc
    49021 tttattggtt ggtctatctt atgctaaagc acttgcatat actttgaata ttccacttgt
    49081 aggagtaaat catatagaag ggcatctaag tgcaaactat atagagcata aggatttaaa
    49141 acctcctttt ataacattaa tagtatctgg aggtcatact cacttggttg aagtaaaaga
    49201 ttatggcaag tatgaaattt taggaaaaac aagagatgat gcatctggag aagcatttga
    49261 taagatttca agagctatga atttaggcta tccaggaggt cctattattg ataatctggc
    49321 caagaatgga aataaacatg ctatagaatt tccaagagcc tatttagaag aagatagcta
    49381 tgattttagt tttagtggat taaaatcttc tgtattaaat tatctaaatg gaaaaagaat
    49441 gaaaaatgaa gaaatagtag ttgaagatgt agcagcatct ttccaagagg ctgtagtaga
    49501 ggttttatct aataaagcac taaaagcagt aaaagacaaa ggatacaata tcataactct
    49561 ttctggtggg gttgcttcta attcggggct tagagctaaa ataacagagc ttgctaaaga
    49621 caatggtatt actgttaagt atcctcctct aattttatgc acagataatg cagctatgat
    49681 agggtgtgca ggatattata attttataaa tgggaaaacg catgatatga gtttaaatgc
    49741 agttccaaat ttaaagataa atcagtagag ttagatgaat ttgtaaatat aaaagtattg
    49801 tttcaaaaaa gtaagtagaa gtgaaattaa atataataaa aataaatata gtatatatta
    49861 aaacttgaag taaaactatt tataatcttt atattccaat gaattgcaac aaattttagg
    49921 atatacagat tgtctttggc ttagatttgc ttcaagttta attttttcta tagaaagatt
    49981 attttaaaaa gtgggtaata tacccttttt tttcattctt aaaaagtttt atactaatta
    50041 tagaaagatt aaggagggga agaaatgagt caaagtaaag aagacaaaat aagaagtatt
    50101 ttggaagcaa aaaatattaa atcaaatttt caaaataaag aaaatttaag tgaatttaat
    50161 gaaaaaaaag caagtaaaag agcagaagac ttattagatg tatattataa tacattatct
    50221 actgctgata tggaatttcc atattggtat aatagagaat atagaaaatc agatggtgat
    50281 ataccagtag ttagaagagc taaagctctt aaagctgctt tttcacatat gacaccaaat
    50341 ataatacctg gtgagaaaat agtaatgcaa aagacacgcc attatagagg ttcttttcca
    50401 atgccatggg taagtgaaag tttctttgtt gctcaaggag aacaaatgag agaagaggca
    50461 aagaaattag ccagtaacac agctgatgaa cttacaaaat ttgggtctgg tggaggaaat
    50521 gttactgaaa gttttggaaa tgtcgtttca atagctggta aattcggaat gagaaaagaa
    50581 gaagtacctg tacttgtaaa aatggcaaag gaatgggttg gaaagtctgt tgaagattta
    50641 ggttttcact atgaaaaaat gatgccagat tatgatttaa aagaaaacct aatgagtaca
    50701 cttatatgca tgtttgattc agggtataca cttcctcaag gtagagaagt tataaattat
    50761 ttttatcctt taaattatgg attagatgga attatagaaa tggcaaaaga atgtaaaaag
    50821 gcagttgcag gaaatgcatc tggagatggg cttattggta tggaccgtct atatttttat
    50881 gaggctgtta ttcaagttat tgaaggatta caaacttgga ttttaaatta tgcaaaacat
    50941 gcaaaatatt tagaaagtat agagacagat ttagaagcta aaaaagaata ctcagattta
    51001 gtggagatat tagaacatat tgcacataaa caacctcgta catttaggga agctcttcag
    51061 ttgacttata caattcatat agcatcagta aatgaggatg ctatatctgg tatgtctata
    51121 ggacgttttg gtcaaatttt atatccttgg tatgaacaag atatagaaaa aggactaatt
    51181 acaaaagaag aggttatcga attattagag ctttatagaa taaaaatcac ttgtattgac
    51241 tgttttgctt cagcgggcgt aaatggagga gtactatcag gtaatacatt taatacttta
    51301 tctataggtg gattaaaaga agatggttct acaggagcta atgaactaga agagttatta
    51361 ttagaagcaa gtatgagatg tagaactcct caacctagtt taactatgct atatgatgaa
    51421 aagcttccag aagatttctt aatgaaagct gctgaatgta caaagcttgg ttctggttat
    51481 ccagcctggg taaacaactc aaatggaaca acatttatga tgaaacaatt tgctgatgaa
    51541 ggtatgactg ttgaagaagc aagagcattt gcattaggtg gatgtttgga aacgtctcca
    51601 gggtgttgga aacagttaac tttaaacgga aaaacgtact ctattgcagg tggagcaggt
    51661 caatctgctg gctctggagt tcactttata gctaatccca aaattttaga acttgttctt
    51721 atgaatggta aagaccatcg tatgaatata caagtatttg agcctcataa taagccatta
    51781 gatacttatg aagaagtcat agaagtattt aaagattatt ataaacaagc aataaatgtt
    51841 ttagaaagag caaataacat tgagttagat atatggagaa aatttgatac ttctataata
    51901 aattcactac taaagccaga ctgtttagac aaaggtcaac atataggaaa tatgggatat
    51961 cgttataatg caacattaaa cgtagaaact tgtggtactg ttactatggt caattcattt
    52021 gcagcactta agaaacttgt atatgatgac aaagcattta caatagagga aatgaaggat
    52081 gcaatattaa ataattttgg atttaaagat gcattagaag taggaaatta ttctatggca
    52141 gaccaagtaa aagtagataa gactggtaaa tatgatgcta tttacaaggc ctgtcttgat
    52201 gcacctaaat atggaaataa tgatttgtat gcagataata ttcttaaaaa ctatgaggta
    52261 tggttatcaa aagtatgtga agaagcacaa tctttatatg ctaagaagat gtacccttgc
    52321 caaatatctg tttctacaca tggaccacag ggagctgcta ccttggctac tccagatggt
    52381 agactaagtg gaacaacata ttcagatggt tcagtctctg catatgcagg aacagataaa
    52441 aatggagtat atgcattatt tgaatctgca actatttggg accaagcagt agttcaaaat
    52501 tctcagatga atttaaaact tcatccaact actataaaag gacaacaagg aactaaaaaa
    52561 ttattagatt taacaagaag ttatttaaga aaaggtgggt tccatattca atataatgtt
    52621 gtagattcag aaacattaaa agatgcacaa aaaaatcctg acaattatcg tcaattaatg
    52681 gtacgtgttg ctgggtttac tcaatattgg tgtgaattag gtaaaccaat acaagatgaa
    52741 gtaattgcta gaacagagta tgaaggggtg taaaatatga gaaagcatag tgattgtatg
    52801 aatttttgtg cagtagatgc aaccaaagga atttgtagat tatcaaaaca aatgattaat
    52861 ttagatgatt cagcatgtcc agagataaaa gtaatgccaa aatgtaaaaa ttgtaaaaat
    52921 tttgttgaag ctaatgatga aggtataggc aaatgtgttg gcctagagaa agaagactgg
    52981 gtatattcaa cattgaatgc aattacttgt gaaggacatg tgtttaatga gtagtcaaaa
    53041 gcaattagaa ggcatgattt tcgatgtaca aagcttttca gttcatgatg gtccaggttg
    53101 tagaacaact gtatttttaa atggatgtcc actgagttgt aaatggtgtg caaatccaga
    53161 aagttggact gtaagaccac atatgatgtt tagtgaatta tcttgtcaat atgaaaatgg
    53221 atgtactgta tgtcatggta agtgtaaaaa tggtgcattg agctttaatc ttgataataa
    53281 gccagttata gattggaaca tctgtaagga ctgtgaaagt tttgaatgcg tcaactcatg
    53341 ttattataat gcgtttaaat tatgtgcaaa accttatact gtagatgaac ttgtgcaggt
    53401 aattaaacgt gattctaaca attggagaag taatggagga gtaacattta gtggaggtga
    53461 gccactactt cagcatgaat ttttacatga agtattatta aagtgtcatg aggtaaatat
    53521 acacactgcc attgaaacaa gtgcatgtgt atcaaatgaa gtttttaata aaatatttaa
    53581 agatattgat tttgcattta ttgatataaa gcatatggat agagaaaaac acaaagaaca
    53641 aacaggtgta tataatgatt taatattaga aaatatatca aaccttgcaa attctgactg
    53701 gaatggaagg ttagtactta gagtaccagt tatctctggg tttaatgata gtgctgaaaa
    53761 tataagtgat attatatctt ttatgcacaa aaataattta atagagatta acttattacc
    53821 atttcatagg ctaggagaat caaagtggat tcaattaggt aaggagtatg agtattctga
    53881 taagggagat attgatgaag agcatcttga agaattacaa gatatatttt tggataatgg
    53941 tatagcttgc tatgttggtc atgagacagc tttttaaaat caaatacaag tttttttaat
    54001 taaaaaagga tgttacacta aaagctagag ttacatcctt ttttatgtgg tttttatgta
    54061 gaaataatta agtaaagttt tatatgtttt atatattgtt catattgctt tatgtccata
    54121 aatattactt taaatttata ctttatatat tttttatagt ttaaattaca gttagagaat
    54181 atattacgtt tactttattg aagcagaagt tttgtggtaa aatactacta tgaagaaatt
    54241 taatagaata tattttagaa acaactaaaa ataatagtta ggaggaagac atctatatga
    54301 acaaatcatg gagtaacttg attattaaga ataaagacaa aaaagtacgt tcagggtgga
    54361 ttattataac tgttatggct gccttttaca tatttgagta ttatttaagc actatactta
    54421 tggaaataat aagaaaaatt ctgattgcta caggtgacat taatttaaaa acaaactatt
    54481 tttcggaata tgctaattgg ttaaatgacg ttgggttaca ggttgtattt caaattctaa
    54541 cagattcact tatgattatt attcctataa ttgtatggag atttattatg aaaaatccta
    54601 ttagtgaaat gggattacat tcttatagaa ttaagaaaaa agaaggatat gtaggaatgt
    54661 tattaggaat atttaattgt acagtaatct ttattataac aataacaatt ggtggtggtc
    54721 atgttacttc atgggtacca aaaatttcac ctttaacagt ttcttggata cttgtcttta
    54781 ttttagttgc ttttgcagaa gaaattttaa atcgtggttt ttttatggca gttttacgaa
    54841 gatgtaaaaa tatttatttt ataatgattg ttccatctgt tatttttggg ttgattcata
    54901 tatggaatcc tgatgttact tttttgtctg taattaatat tataattatt gggattcttt
    54961 tttcatatat gtttataaag tcgtcgaata tatggatgtg tataggttat cattttacat
    55021 ggaatgtatt tcaggggatt atatatggta tgcctgtaag tggacttcag gttccaggga
    55081 ttataactac acaaatcact catggtaatc tattaaatgg agggatgttt ggtattgaag
    55141 gtggaatttt gactactttt gttaatctac ttagctttat atttgtatgg tattactata
    55201 gagattctaa gtatgatttt gttagtgata aagtaaatgt gactaatatc aagaattagt
    55261 tgattataat aaattttaat aatatcttct aaacttaaag tattctgtag gattgttgga
    55321 aatttacaaa aatataaaaa taacttggat attctattta ctccaagtta tttttatatt
    55381 cttttgtaaa tagaaatgga acataaaaaa ttaaaacaac catagatact attagtatat
    55441 catggtaagt gatagttgat tctttagaat ttgtgataag aaaagcacta ttatttaaaa
    55501 catgaattat agcacaaaac cagatattct tagtttttat ataaagatat cctaaaaata
    55561 ttgaaattcc aactatatgt attgaacgta atattactcc taatattggc gcttcaggtg
    55621 tatataatgt aaatattagt ggtaagtgcc acaagctcca acacatacct aatattatga
    55681 ctcctaattt tttaccaaat ttatcaaaaa aaatattctg taaaaaacct ctccaggcat
    55741 attcttcact aaaaaaaata taaatagtag ttaatgatgt tattggagta aatataaatt
    55801 ttatgatacc actataatta ggttgagccc cttgtagtat tagtataaat gatgttggaa
    55861 caattacaga aatcataaag taaataatta ataaagaacc tagtttaata ttttttacag
    55921 gatataaatt ttttttattt gatgaatata ttataattga taa
//
LOCUS       DAMJWO010000011        55783 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.012, whole genome shotgun sequence.
ACCESSION   DAMJWO010000011 DAMJWO010000000
VERSION     DAMJWO010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 55783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55783
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.012"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            58..867
                     /locus_tag="PC366_000764"
     CDS             58..867
                     /locus_tag="PC366_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2576304.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKEN
                     IIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKMYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITK"
     gene            1012..1251
                     /locus_tag="PC366_000765"
     CDS             1012..1251
                     /locus_tag="PC366_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576305.1"
                     /translation="MKCSNCGSVNIEKGILTTGGIYAETIGLKYRGDGKLDKVINKTF
                     PVQSTIYSDLCLDCGEIVRTYIKDNTDRNWCKDKK"
     gene            complement(1439..1615)
                     /locus_tag="PC366_000766"
     CDS             complement(1439..1615)
                     /locus_tag="PC366_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576306.1"
                     /translation="MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(1669..1765)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(2120..2794)
                     /locus_tag="PC366_000767"
     CDS             complement(2120..2794)
                     /locus_tag="PC366_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDF2576307.1"
                     /translation="MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     STDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     gene            complement(3014..3568)
                     /locus_tag="PC366_000768"
     CDS             complement(3014..3568)
                     /locus_tag="PC366_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDF2576308.1"
                     /translation="MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNL
                     PVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIIIKHTPDSFFETDLQSILEK
                     KNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQV
                     FMASLQNSFADVKNTDKFLSNYHK"
     gene            complement(3646..4011)
                     /locus_tag="PC366_000769"
     CDS             complement(3646..4011)
                     /locus_tag="PC366_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2576309.1"
                     /translation="MKIRAEYTCPLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNI
                     YGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEY
                     MLEHGQQEILDNKGICYNK"
     gene            4476..5261
                     /locus_tag="PC366_000770"
     CDS             4476..5261
                     /locus_tag="PC366_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2576310.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVEDGNITSIILKNKSTLIIYSFKNNFDIGEMKNHIKDLDVESISGKKCVIDRLISK
                     YKDFYEKLDNKFCVLKEIKEIDFSNMKEYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKEHLKEGNVRAYFIRNDDTMISTVSTGMETSFLAMVVSVSTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDVAGKIYHNIGYKEINEWTILFK"
     gene            complement(5632..6810)
                     /locus_tag="PC366_000771"
     CDS             complement(5632..6810)
                     /locus_tag="PC366_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDF2576311.1"
                     /translation="MKTNKISFNKGLYYLNTNANFNFQLNRIIMWDGGRLEDIQKVSS
                     KIVDSESWKTELMYLAQEAEQDGRTENAIAYYRMSEFFMYDGDPDKISVYKKATTLFY
                     NYYSEYFSNGTVQIFHVPYENITLPVMYAKAQGEVKDVILLHGGNDSYFEEFFFPMLY
                     LASQGFDIYLFEGPGQGGVMRLQGKHFTYQWERPVKTILDYFHLENITIVGASLGGFL
                     APRAAAFEKRIERVVAWSVFPNFLDIIVGSQPIKMQNLLRLLLKLKTKWLVNFIIKQK
                     MKSGDSMVVWGLKHGMYAYEASTPYEYFQKIKYYQIDSIAKNINQDILILGATQDHFI
                     DYRTVGKEIDLLNNVRSLTFRLMTEAEQASNHCNCGNSKLVLDTISNWIMMMKIHDRV
                     "
     gene            complement(6913..7677)
                     /locus_tag="PC366_000772"
     CDS             complement(6913..7677)
                     /locus_tag="PC366_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2576312.1"
                     /translation="MTTICVMIDHIFLDTEYRQPTIHKHLAKHIIISQSGNLSVTFDK
                     GESLQCKGIIIDSNVSHTVSSKDNKMLVFLIDDTSILAQNISQHQLLNHSFFVIDNLI
                     VERIQNIYTACQVKGLSQSYIDFSKQAFRLLNLNYHISSITDSRIQWALNHILKSTHI
                     HNEIFFEICAEVKLSKSRFSHLFKEQMGVSLNSYLALSKLRKAYELLLKSGDITSAAM
                     DAGFSSPSHFSASSKKYLGITASELIGKCKIYFIRQ"
     gene            complement(7866..8690)
                     /gene="pdaA"
                     /locus_tag="PC366_000773"
     CDS             complement(7866..8690)
                     /gene="pdaA"
                     /locus_tag="PC366_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HDF2576313.1"
                     /translation="MKKDSLKKYIMIGAFALILFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYGAYYVGNPNEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPELIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEKEGYKLKTLDYLNNKK"
     gene            8911..12030
                     /locus_tag="PC366_000774"
     CDS             8911..12030
                     /locus_tag="PC366_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDF2576314.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIYTY
                     ESLIKNKFEVPIEVFSVCKNLDKNDLEIANEIELVEDRLVNFVEDSFIICHDLSLKKK
                     FFEYHMPKLKNKFIDLIELAVILEPYHKDYSLEYLKNTLTNCNSKVENRALSDAIDII
                     NIVNCLLVKFNNYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINIKK
                     EYNIFDSKEEKKKERETLKILNEEEKNYEELLKYKTIWENKEGFTYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLK
                     RLVEGGKYGDIEEINYLVFDNFKEISTHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIGREDKQKIARSINLIIEEIDSIL
                     KFGNCNEYNNVSNYNLRWELNLQIDEIVGKLKKDGIDTEISYRAYSEKIKLSCEKIIK
                     NLVSIIIIIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIV
                     EIDKNYNDFEFRVVPLKIADLFEENILSQLEKGIFLSATLSLSESMSYFKNTLGIDRV
                     KNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSKIISNISKITEGHTLALFNS
                     KDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGL
                     VCVTLDKLPNLNPKDPLYFTIMKKYGIDYYTINYPQMTIKVKQAMGRILRSKYDYGCF
                     VIFDVGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRRHLNKSRSLILKSVIFDTIKA
                     LNVDAKMDNNDVDKDIIKKDINENIRQRAVKGEVYHIDIIKKDMKVKYFDRNYLINLD
                     IFMREEDKN"
     gene            12048..12647
                     /locus_tag="PC366_000775"
     CDS             12048..12647
                     /locus_tag="PC366_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H family protein"
                     /protein_id="HDF2576315.1"
                     /translation="MAKQKFYAVKKGKNIGVYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIDGSEKLSFQEDKEFIEAYVDGSYEHSVKMYGSGVVILKNNEVIKTYSEKGKEK
                     TLVSMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(12904..15033)
                     /locus_tag="PC366_000776"
     CDS             complement(12904..15033)
                     /locus_tag="PC366_000776"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HDF2576316.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGPIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNDEE
                     VSKKIDNTCSWKKEHTKNIENECNCEHEHHDYLNKALDCKQEHKTDIKDDCNHEKKHT
                     KNTNKVHNSKQDKFKDKSCDEMNFNYDKDESCDKINSSYNKEDSSYEDFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKGEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGITSRPQDRENFTLLLTAIR
                     DVIGDDKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNGRKHQAN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPYLVKDGDFAMSYDDALSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            15299..15547
                     /locus_tag="PC366_000777"
     CDS             15299..15547
                     /locus_tag="PC366_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576317.1"
                     /translation="MMICFAMTFALVLINSVMGVHIGLDYYFLMGSVLTVCLTIGIVL
                     CNARKIFDSKAIHKTRTKTVSTNKKQKSHSRDIKRKIS"
     gene            15713..17104
                     /locus_tag="PC366_000778"
     CDS             15713..17104
                     /locus_tag="PC366_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HDF2576318.1"
                     /translation="MNFRDLFEKAVDFIDEKRKSIVAISLSTLGVIALIIVFFLSSNE
                     FSVGNEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELNKISIDVDDLLAQADRVREMYKEENTTYDIAINYIS
                     TVSILNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKAYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKEDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNTLDEKE
                     NKYKKIEILDIEKADRYVKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAISENGLNEY"
     gene            17219..18688
                     /locus_tag="PC366_000779"
     CDS             17219..18688
                     /locus_tag="PC366_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HDF2576319.1"
                     /translation="MSNVNKKLVIAIGAVALVAIIFIGIMCMQFKGEKIAKNTYVNGV
                     DIGKLTKSQAKQELAKKYKLENVEFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SSFFGNLSKTISTNFGKKSNLVVVINYDKNKLKAEMEKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDISKSMENFDNQTKKGNYKNELVVKATPAKVKKEQLTNIDTNLGTY
                     STIFKTSQINRSINIKLATDNISNVLLMPGETFSFNKHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIVNVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPN
                     TDENKNNQNTNNQNPNNQQKPETPPTDNKPNETQPQPQA"
     gene            18753..19346
                     /locus_tag="PC366_000780"
     CDS             18753..19346
                     /locus_tag="PC366_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HDF2576320.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            19528..20874
                     /locus_tag="PC366_000781"
     CDS             19528..20874
                     /locus_tag="PC366_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2576321.1"
                     /translation="MPRKILDISLIEDNKSDLTFFNIEEEDGDETLKALKQSYVTTNY
                     KEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKNYITSAINMVNKALEINP
                     KDIDILNLRGLLKLLKCDFAKSFESFYTALCYENNHISRKYVNLISSEDFKTFLGRYN
                     HSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDKLGNVKKREGYLDKLKEL
                     DKDNPVFEKNEEEKEDTSKKEEIRKVKRKKSILPYIIVGCVLIGMGIYLIQSKKRIEN
                     LNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEPEREITVADEEDLYYQAL
                     NLKKNKEYEKAIDNFKSVVSSGKTKKYISESIYQLAITNKLLGNKDEAIKYYKKYINT
                     YTKNDQYYDDSYYELGMLYYDNGDLKNAQQTFYSLRSEVPDSMYNNSKIKEILSEK"
     gene            21056..21427
                     /locus_tag="PC366_000782"
     CDS             21056..21427
                     /locus_tag="PC366_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HDF2576322.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            21420..22109
                     /locus_tag="PC366_000783"
     CDS             21420..22109
                     /locus_tag="PC366_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HDF2576323.1"
                     /translation="MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGIESITVVAIIFTGIF
                     GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            22629..23495
                     /locus_tag="PC366_000784"
     CDS             22629..23495
                     /locus_tag="PC366_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2576324.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISNIIPIHDILLQSVYGGILSGLGVGVVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSNEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            23737..24546
                     /locus_tag="PC366_000785"
     CDS             23737..24546
                     /locus_tag="PC366_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576325.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVNKEIRSIKNMKKRVLKKGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYVGKFLEGKMEGQGSYTFFVDEGT
                     AMEYIGEFKEDKKNGKGNFVFSNGNEYIGHFEEDMMNGIGNMLYNSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEVLYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            24689..25753
                     /locus_tag="PC366_000786"
     CDS             24689..25753
                     /locus_tag="PC366_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDF2576326.1"
                     /translation="MKRLIALVLVILIVLFYSPELIEEGYDLKEKFFQSEIWNEFLDK
                     ININNNSKKDKKEQNQNLQSNNTEGENLGESDIKNFEKISLGDNLSYVLSSIGKPGRI
                     DISEYGFDWYVYNQYGKEFAMVGLENDEVVALYSNSINSCENQDIKLNQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEENRVCSYLIIDKSTEDEFK
                     KLYPDDREELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSRKHSEDMRDNNFFD
                     HINKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            25781..26500
                     /locus_tag="PC366_000787"
     CDS             25781..26500
                     /locus_tag="PC366_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2576327.1"
                     /translation="MTSWKKKTVYKCLIAVVLFCGIVLISNFSKVSALMMDTNGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKDLI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVKNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            26524..27108
                     /locus_tag="PC366_000788"
     CDS             26524..27108
                     /locus_tag="PC366_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HDF2576328.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGEAVVVKRNNEIKISDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICLGHQTIGYVFGGDIIKAQQPVHG
                     KVYSINHTNKGVFRGLKNPLNVTRYHSLIIDSNTVPKELEITAITDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLENFITEARERVHM"
     gene            27110..28459
                     /gene="pabB"
                     /locus_tag="PC366_000789"
     CDS             27110..28459
                     /gene="pabB"
                     /locus_tag="PC366_000789"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HDF2576329.1"
                     /translation="MIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRT
                     AVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDDIEQRILKEEKKG
                     IDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDTHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKE
                     EDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            28449..29192
                     /locus_tag="PC366_000790"
     CDS             28449..29192
                     /locus_tag="PC366_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HDF2576330.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIRVKNGIAVDLDIHIERMLSSIN
                     CLDLDINYKKDFLINEIVTYIKKENVINKALRITVFDEGYNISIRDIPYNQETYEKGF
                     KLAISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FIKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIVKLLE"
     gene            29226..29927
                     /locus_tag="PC366_000791"
     CDS             29226..29927
                     /locus_tag="PC366_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576331.1"
                     /translation="MIGCIYEVYNEEMTKIIENQNTLAVYLVGSSKDVDFTLYDVEIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDVNYFSKDGVKKLLSNREYFFVKEMKDAKVLF
                     DRENISNIIKDISRDIYLEGPSKMSLEEKSFIKQDIGAKISNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELASKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            29953..30525
                     /gene="folE"
                     /locus_tag="PC366_000792"
     CDS             29953..30525
                     /gene="folE"
                     /locus_tag="PC366_000792"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HDF2576332.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLSEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            30591..31382
                     /gene="folP"
                     /locus_tag="PC366_000793"
     CDS             30591..31382
                     /gene="folP"
                     /locus_tag="PC366_000793"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HDF2576333.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELEIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKVSIEMA
                     MSCGVKKEKIVLDPGVGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            31393..31758
                     /gene="folB"
                     /locus_tag="PC366_000794"
     CDS             31393..31758
                     /gene="folB"
                     /locus_tag="PC366_000794"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HDF2576334.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYNVVKDITENKQFNLLEALAENIAEEVLNKFILINGVMVRVRKPEA
                     PVNGIYDYFGVEIRRTRDE"
     gene            31751..32257
                     /gene="folK"
                     /locus_tag="PC366_000795"
     CDS             31751..32257
                     /gene="folK"
                     /locus_tag="PC366_000795"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HDF2576335.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERELHRERIVHWGPRTIDVDILFFN
                     DVASTDERLTIPHPRIQDRAFVLIPLMDLNEELIINEKTVKEHLNLLSAEEREEVKEL
                     VGYERKPI"
     gene            32238..33023
                     /gene="aroF"
                     /locus_tag="PC366_000796"
     CDS             32238..33023
                     /gene="aroF"
                     /locus_tag="PC366_000796"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HDF2576336.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLKILKAVKDEVGMAVITELMDVRD
                     IDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            33278..35068
                     /locus_tag="PC366_000797"
     CDS             33278..35068
                     /locus_tag="PC366_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDF2576337.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMNIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDVINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLDCGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGILIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            35086..36252
                     /gene="rpoD"
                     /locus_tag="PC366_000798"
     CDS             35086..36252
                     /gene="rpoD"
                     /locus_tag="PC366_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HDF2576338.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            36417..37106
                     /locus_tag="PC366_000799"
     CDS             36417..37106
                     /locus_tag="PC366_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF2576339.1"
                     /translation="MKLTDRLLKIASLVSDGKKIADIGTDHGYIPVYLLKEGKVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFNDFIEKKIKTYSSIVNKLEGKNGEAIDKKRKESE
                     VAIKKLENLIK"
     gene            37120..38217
                     /locus_tag="PC366_000800"
     CDS             37120..38217
                     /locus_tag="PC366_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HDF2576340.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSGDLKGRLIQKLIKNDISLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDITKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSIEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSRKIKEKLNMKHIRVVGNLS
                     TDITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEFSEIEVIKSNVYLNPFSTI"
     gene            38279..38851
                     /locus_tag="PC366_000801"
     CDS             38279..38851
                     /locus_tag="PC366_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDF2576341.1"
                     /translation="MKVAVIFHSVCGSTYLLAREYKEVLEEMNIEVDIFRVSDEVAKT
                     LPQYYLINYKEYKDEFESINVIKSGKEILDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGAPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSVRGGYPAYG
                     ILHIAGDNSDIRPNDDAKIGIRDYLKRLNI"
     gene            complement(38911..39378)
                     /locus_tag="PC366_000802"
     CDS             complement(38911..39378)
                     /locus_tag="PC366_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDF2576342.1"
                     /translation="MFKEMRLKKREMTKEDTVEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFNDSIYFHCARNGHKLDNISKNNKVSFLVVANESVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDMNLTTVVKIEIDHISGKASRI"
     gene            complement(39764..40240)
                     /locus_tag="PC366_000803"
     CDS             complement(39764..40240)
                     /locus_tag="PC366_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDF2576343.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLRVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            complement(40360..41451)
                     /locus_tag="PC366_000804"
     CDS             complement(40360..41451)
                     /locus_tag="PC366_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HDF2576344.1"
                     /translation="MSKIECLFTIFPVLILMYATFYFMPYFVGKKHIYGVSIDQEHKN
                     YNYFIKLDKEFKKLLSLGFIIDFILVFILVFTFNKLELSYFIGIIGFLLYESILYIHT
                     HKKAKKLKSEIYSKLGHIDVDSKLIVDMDFINKKNKIIKKFKIIYLIPILFTLGMSIF
                     IAFNYNKLPDSIATHWNINGSPDVFIDKSFLNVFKLIGTDFCLMVLLYITSIGSIKSR
                     IKIDTNRIEESRVENIKYLNKIGYLFLILMIIMTTQFFTTLLSIKTKLSTAMNITTLL
                     VIIYLIATYINSPNLKFNSSYSPEEDEKYWIAGIMYNNPNDPSLMVNKRFGIGWTINF
                     GNPLGKILYIAIALLLIFSLFSLIKSLLL"
     gene            complement(41444..41833)
                     /locus_tag="PC366_000805"
     CDS             complement(41444..41833)
                     /locus_tag="PC366_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2576345.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDKYEVKYYE"
     gene            42025..42471
                     /locus_tag="PC366_000806"
     CDS             42025..42471
                     /locus_tag="PC366_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576346.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMITGAVITGVGAYAVYKMVKSHK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKEDIDLHEDAKKDNIYKEDEYKKYEEE"
     gene            42735..43460
                     /locus_tag="PC366_000807"
     CDS             42735..43460
                     /locus_tag="PC366_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2576347.1"
                     /translation="MKRKEIVMLKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSG
                     KEMISSNEYSMILLDVTLPDGTGYELCKYIRGFSQVPIIFLTACDEEVNIVMGLDIGG
                     DDYITKPFRIRELISRIKAVLRRKGNTSEENKKILKFGDLSIYTLEARVYKNDKEIFL
                     TSVEYKLLLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCE
                     PIYIETVRGIGYKWIGSENSVSI"
     gene            43447..44691
                     /locus_tag="PC366_000808"
     CDS             43447..44691
                     /locus_tag="PC366_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2576348.1"
                     /translation="MFLYNPEVKKFLSKYVTLMFIVIIISIGFSIINVSLTKEMVVRN
                     NQAIIGTLSSKYPNLESQIVDIITQGKSMKNIDYGQKILSKYNYDKSIKINSEPIISK
                     LVLETIKINIILVCIIFILIFVLVVRYFTSIYNDLSDMTKYVYYSSEGKPFDMKNKNQ
                     EGQIGLLKTELLKMTTILNEKVELLKREKIFLNNTISDISHQLKTPMTSLIMLNDLLY
                     NDVPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHRAML
                     SMKIPMEIKNQKLTIEGNDNVSYIGDIDWSVEALVNIIKNCVEHTPEFGNIIITYKEN
                     PLFSELIIKDEGEGIDKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNGDIY
                     VNSEKGKGTEFHIIFHKMYDSD"
     gene            44771..45448
                     /locus_tag="PC366_000809"
     CDS             44771..45448
                     /locus_tag="PC366_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2576349.1"
                     /translation="MEILRVENLTKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLGLIDREKHLPNQLSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            45449..48010
                     /locus_tag="PC366_000810"
     CDS             45449..48010
                     /locus_tag="PC366_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2576350.1"
                     /translation="MNLYTSLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQMRETIKNDGSFHVTFYDVNRKNVEYVTKSAEIEKHAFTKQLGYSKLENSENAILS
                     IKQYDQNAINGYKVSIKEGRFPAKEGEIVLSESIINLIDDKLKIGDKITLKVGDMFDS
                     SKKKIDSMTFHEGDYIANEKDRTFKVVGIIKKPGFERYNGIATAIAYFNPMNNYNDTI
                     NVSVAVRNPKDVYKISNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYSNINSSI
                     KSIIIAVTILVIICTIATVYNSFSISINERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTKMSLQIVYNPIIIIVSIIIVLLTIF
                     ISILLPAISASNISPLNVIKNTGEYKVGKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IITLFSLMVSIIIFISFSGFTLLLLRGEEIRNSQRKYDLYLTAKNTARSVEDTISELE
                     DIDGIKNFELATGQYVSIRVSENKINKSKEDLIRKYYQKYKIGESYEYDFSNNELIFP
                     GDFAVKNKINNLVQGSFNKERAIEENGVILVRKSAIEENGKKGVVELTNYKVGDTVNC
                     EYLDENALSKKVKVKILAITDEERLGFGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNDFNFYDEISSSESEKQDLKVIKIFVYGFIVVISLVSVTNI
                     LNTVSTSINLRKRELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGIILIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPMSKLNKENIIDNIRRESI"
     gene            48231..49505
                     /locus_tag="PC366_000811"
     CDS             48231..49505
                     /locus_tag="PC366_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2576351.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKIECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHENCVKCGKCITACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILASKQLKSVYLDKLLSMNDK"
     gene            complement(49666..52707)
                     /locus_tag="PC366_000812"
     CDS             complement(49666..52707)
                     /locus_tag="PC366_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HDF2576352.1"
                     /translation="MFKQRISKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNAESYTKTKALAKEKIQTLLSKYGAVSAQYALIDNGKIEISGNGGVYSKQD
                     NKNLNKDNMYSIASISKMFTTTAVMKLVDDGKLNLDTPVVKYIPEFKMADDRYKEITP
                     RMLLNHSSGLMGSSFKNTILLADNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTTENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGSSQLNEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSSLKENSGLYASSNMIKVDVNDNG
                     TLTVSSPYIENGPEDKYVYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKVDDNNISNSVKEVWKKRSGKGYYLVDEKYTSQSYMFGSVKASFSLSD
                     ETPGYIVNTKIMDENNSNAFIEIPGVIGRDLSDIKLHKENGTEYLSFGTLTYVSEDSI
                     TNLPAEKSFTCELESNGYAKWYKIGDDIANKKIEVNLPQNSAFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGEA
                     SINEKSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNLFKNKKIDKSYVIGGEYTVSKNIESKLQNPQ
                     RISGNTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVM
                     LVGNSLDYNQKELFKTMRFKSVTQIGGNGNENSFKQIKEIA"
     gene            52914..53213
                     /locus_tag="PC366_000813"
     CDS             52914..53213
                     /locus_tag="PC366_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDF2576353.1"
                     /translation="MYKNINKKQLKEMMKNEKDVLLLDVRTKDEFKEYKIENAINISL
                     QDLINNIDEIYDYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMS"
     gene            complement(53451..55679)
                     /locus_tag="PC366_000814"
     CDS             complement(53451..55679)
                     /locus_tag="PC366_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HDF2576354.1"
                     /translation="MRHLKKTNSLKEILNWNNIKNLRPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITDDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNDTLVDFLTKLNQLTSNNRLDDVIDNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSISALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAEAKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIDTLSKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIVLLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRVIKPFNDKFGDSNLT
                     GH"
BASE COUNT        21997 a         6156 c         9137 g        18493 t
ORIGIN      
        1 agagtaataa tgttgattta aaataaaaat aggatttcgg aggagtttat tatataaatg
       61 aaagattact ataaaatagg agagatatct aaaatatatg gaataggtag agattcatta
      121 atgtattatg aagaaatagg cattctaaga ccagttagag atataaatgg atatagaatg
      181 tataatatat cagatatatg gaaattaaat ttaataaaag aatttagaag cttgaacttt
      241 ccaatgaaga aaataaaaga atacctagat gacagaagta tagagtctac gaaaaatatt
      301 ttaaatgaag aactcgattt aattgataaa aaaatagctg aatttataag ccataaggaa
      361 aatattataa aaagattgag ttcgattgaa agtgtaattc aaaatacaaa aatagatgag
      421 atagaggttg tatatataga aaaaagaaaa gctttagaat taaatgctga tataaagagg
      481 gatgaagact tcgatttttt aattcagaaa cttcagaaag aatatgaaga tagatttaat
      541 atacttggaa acaacaatat tggttctgcc ttttctactg aagcaattaa taaaggtata
      601 tttaatgagt ttaaatctgt attttgtttt ctggaaagta atgagaaagt atataatata
      661 gtttttgatg aaggatatta tgtaacttta aattatactg ggagtaattc taataataag
      721 atgtatatgg agaaggtgtt taaatttata gaagaaaata attataagat aattgctgac
      781 cctatagaaa tctataagat agatatacat gagactggaa ttgtagaaga gtttgtaacg
      841 gaaattcaag ttcctataac taaatagcca tatttcaatg gattagatgg taaatagaat
      901 gaaaaaatgt tgatttgcca ccgatttgct actgtgttat aaaatcggta gcaaattata
      961 ttttaaatta taagatagca tgaaaaaata attgtttagg gggttataaa tgtgaaatgt
     1021 tctaattgtg gaagtgtaaa tattgaaaag ggtattttaa caactggtgg catatatgct
     1081 gaaactattg gattaaaata tagaggagat ggaaaattag ataaagttat aaataaaact
     1141 tttccagtac aatctactat atattcagat ttatgtttag attgtggcga aatagttaga
     1201 acctatataa aggataatac tgataggaat tggtgtaaag ataagaaata gaataatttt
     1261 tgaagtatat taatatttga agttgaattt tattaaagat acaagtgaaa aagtataaat
     1321 gggaagaaat tgttatatgg aagaaaactt tgcatatagg ggagattagt tttttaatat
     1381 aataacattt ttaaatgtag ataaaactaa aaagggttct ctagaaaaca atttctattt
     1441 aattatactt acttaccaat accatcactt gatgtaaaca agattctact acattttctc
     1501 cgtactctag tataaaatca tctagctgtg tatctataaa atcacaataa tcatataaac
     1561 tactaatata agcagttaac atgtgtgtac atttatccat ttcatctcta aacatatata
     1621 ttactatccc cctaaaaaac tttcataaaa caaaaagaac aatatctttt tggcaactgg
     1681 ctgacataac tcatagttta ttttataagc gttagtccct atagctttgc gtcactaaat
     1741 ttctctagtt ttgccgattt agttttattc tacaactaaa ataatacact aggataagtt
     1801 attgttcaac atacttgtca gaaaattgaa atatttaaca gtatcttaac aatatgaaat
     1861 ctatttttca ctcaagaaac aaactataca tgtagaatat ttaataaaaa ttatatttag
     1921 ttttgtattg aagtttttgt attaaaaagt ttagttcaca agagttactt ggctagataa
     1981 tagatgagca aaaatatctt gaaaaaatat atatgaatgg caaaaaacaa gggatgaatt
     2041 ttatatagac tcatcccgta attatttata tattgacctt gattaaatat attattattt
     2101 ttaagcttca atttttatat tatatttcta aagtttctat aagaggatta tcgctaaata
     2161 attttaataa atttgttttt ttatatcctt taggtaactt agtatatata actacttcta
     2221 accaatcccc atcaaggcgt ttaatattca tgtttataat ttcaatatta gattttttaa
     2281 atttaccttc aatatattct atggaatcag tgctgttaga aattttaaga gaaacttgct
     2341 ctgctgtagg gagtttcatc cacttcctat ctctatgaag tgttatctgt acaataacaa
     2401 taatgatact tgaaacaata ccaactaagt ataatccaga gccaatggca agacctgtac
     2461 cggctgttgc ccatatacca gcagctgtag taagaccact tactgattga tttctaataa
     2521 atattaatcc agcacctaaa aaacctatac cactgacaac ttgtgctgca acgcgggctg
     2581 ggtctagacc aatacctgga gtacccacta tatcattaaa tccatacttg gaaacaatga
     2641 ttataagtgc tgaagctaat gccactataa aatgagtgcg tattccagct tcttttagtc
     2701 tattctttct ctcatatcca attaaagccc cacagaaacc agcagtaatg attcttgcta
     2761 tatattcaaa ttgaatcaat atatgatggt tcatttatct agcaccccct tctatataat
     2821 attatatata ctataatact acatttttta tgtgaatata gtaaagttta aaatttatat
     2881 aatagttata tatgaatata aaatgtataa acgtatatta tgtatataaa aatgatagaa
     2941 agcatctaat tttaaatgat taaagagcaa gcttaaataa atcaaacttg ctcttttaac
     3001 atagtgtatg tttttatttg tgatagttag ataaaaattt atctgtgttt tttacatctg
     3061 caaaactgtt ctgtagtgat gccatgaata cttgatgtac agtatttgca ttaatttcta
     3121 tattattcca agataaattc ttcgttgtac atgcatcgct tattagagtt atgtcgtatc
     3181 gaagtttctt tgctgttctt acacttgtat caatacacat atggctcatc attccacaga
     3241 ttactagatt agtaatattt tttttctcaa ggatactttg caaatctgtt tcaaagaaac
     3301 tatctggtgt gtgtttaatt ataatttctt cattatctag tggaaaaaca attttattta
     3361 tttctgaacc atgagtatta ggaagaaaaa aagaagctgt tttatctgtt gatatatgct
     3421 gtatatgaat aactggtaaa ttgttttttc taaaaaacag tagtattttt ttagcatttt
     3481 cagcagtttc ttctgattga aataattcac attttccatt tttaaaataa tcattttgaa
     3541 tatcaatcaa tattaaagct atagacatga ttataccttc tatttacttt tattataata
     3601 ctattgtaaa aaatgtaaat tacttacttt ttggtatgta taggattact tattgtagca
     3661 aattccttta ttatctagaa tttcttgttg accatgttca agcatatatt cgattcctat
     3721 ttcttgcatt atttccactg cttttaacat ttttttacca cgattagtaa gaaaatattc
     3781 aacatgtaat ggatatccag cagaacttat tttatcaata atcccaaaat cacgtaactc
     3841 ttttaattgt tgaatcaaca ttttttgatt tattccataa atattatgtt gcaattcaga
     3901 aaatgtttta ttagattgtc ttaattcaaa tataaggata gttttccatt ttcctttgat
     3961 tatgtcatgt acaatttcaa gaggacatgt atattcagct cttattttca tagcatatca
     4021 cccccagtaa aatgataata aattatatca cttgtcttgt gatatgacaa atatatatga
     4081 actgtatata aattttatgt tttattaagt tctaaatttc ttctattgta gttcatattt
     4141 agtacataaa taattagtaa gatataagta aataaatata taacatgact atagaaattt
     4201 aactttaaaa taacttatga taatttagag gaggaatata tatgaatata tcaagaaaag
     4261 ctatgaaaat aatagaatta gcacaaaaaa ttgcaaataa gagaggtatt tcagtagaag
     4321 aagcttggag tgaagcagta acagaatata aaaataaata cgaacatatt gcatagatat
     4381 ttaaaaattt agaatatttg gtagaatata atgattttaa atgatactat aaattataag
     4441 gtatatcatt attaacatag aaggaggata tctgcttgat tgtaaaaata gataatactt
     4501 tagaaaaaga attttggcaa tatgtatcac atgaagaaag tttaaattta ttcataattg
     4561 gatacgttga gaattatgga tttagctctc aatatcaaga tatatggtct caggtagaag
     4621 atggaaatat aacctctata atattaaaaa ataagtcaac acttataatt tatagtttta
     4681 aaaataattt tgatatagga gaaatgaaga atcatataaa agatttagat gtagaaagca
     4741 taagtggaaa aaaatgtgta atagatagac taataagtaa atacaaagat ttttatgaaa
     4801 aactagataa taaattttgt gtattaaaag aaataaaaga aatagatttt tccaacatga
     4861 aggagtataa aatagaaaat gctcaggaaa aagatattga tgaaatagga aaacttttaa
     4921 ataggtcaga ctataaagta agtaaaaatt acatagaaga aaggaaagaa catttaaaag
     4981 agggaaatgt aagagcatat tttattagaa atgatgatac tatgattagc actgtgtcaa
     5041 ctggtatgga aactagtttt ttggcaatgg tggtctctgt aagtacagat aaaagatata
     5101 ggggaaaagg acttgcaagt tatatggttt acaatttgag taaagaatta ttgttggaag
     5161 gaaaagttcc atgtcttttt tataataatg atgtagcagg taaaatatat cataatatag
     5221 gatacaaaga gataaatgaa tggacaattc tttttaaata gctataaaaa taataaattt
     5281 tcgtgtaatt cttaacgtgt attgtataat cgctcaaata cttgaaaggt gtctagtaga
     5341 tgggtttgtt agcatttatg gtctccttat ctaagtaaag ttccctttgg aaatcggtga
     5401 aatactcttt tacatttcat gagtcctata aaatctatga cataagaaag acccagttac
     5461 attgagtaat tgggtcttat tatcatatat attgtgtgct tacatgatat agttcatttc
     5521 tataaacgta gtatttcgta agtgggaacc aattttttaa caagtgatta tttgaacaaa
     5581 gcaataagga tatgctagca gatggatttt gtataattta aaaatcaata tttagactct
     5641 atcatgtatt ttcatcatca taatccaatt tgaaattgta tctaaaacca gtttgctatt
     5701 tccacagtta cagtggttac tagcttgttc tgcttctgtc ataagcctaa atgtaaggga
     5761 tcggacattg ttgagtaaat caatctcttt accaacagtt ctataatcaa taaaatgatc
     5821 ttgtgttgca cctaaaatca aaatgtcttg gtttatattt tttgcaatag aatctatttg
     5881 ataatacttg attttctgaa aatattcata gggtgtagac gcttcatatg cgtacattcc
     5941 atgttttaaa ccccatacca ccatactatc gccacttttc attttttgct ttattataaa
     6001 attgactagc cattttgttt tgagttttag cagtagtcta agtagatttt gcatttttat
     6061 tggttgtgaa ccaactatta tgtctaagaa attggggaat acagaccaag ctaccacgcg
     6121 ttcaattcgt ttttcgaagg ctgctgctcg tggagcaaga aaacctccca aggaagcacc
     6181 tacaatagtt atattctcta aatgaaaata atctaaaatt gtcttaacgg gacgttccca
     6241 ttgataagta aagtgttttc cctgcaaacg catcactcca ccttgaccag gtccctcaaa
     6301 aagataaata tcaaatccct gtgacgcaag ataaagcatt gggaaaaaga attcttcaaa
     6361 gtaagaatca tttccaccgt ggagcaatat aacatctttt acctcgcctt gcgcttttgc
     6421 atacattaca ggtagggtga tattttcata tggtacatga aaaatttgta cagttccatt
     6481 tgagaaatat tcagagtagt agttgtagaa tagagtagtt gcttttttgt agactgatat
     6541 tttatcaggg tcaccatcat acataaaaaa ttcactcata cgatagtaag caattgcatt
     6601 ttctgtgcgt ccatcttgtt cagcttcttg tgccagatac ataagttctg ttttccaact
     6661 ttcgctatcg acaattttag aggaaacttt ttgtatatct tccaagcgcc ccccatccca
     6721 cataataatc ctgtttaact gaaaattaaa attggcattt gtattaaggt aatatagacc
     6781 tttattaaaa gaaattttat ttgttttcaa tgtcatcact cctaaaaaga taatgcatag
     6841 caataaagag taatctttaa tgctatgcat ttattgtaac aaatattaga agtactgact
     6901 ttcaaataga cgctattggc ggataaaata tattttacat tttcctataa gctcacttgc
     6961 agtaatgcca agatattttt tgctggaagc tgagaaatga gacggtgaac taaaccctgc
     7021 gtccatagca gctgaggtaa tatctccact ttttaacaat aactcataag ccttgcgaag
     7081 ttttgataaa gccaaatagc tgtttagtga tactcccatt tgttctttga aaagatgaga
     7141 aaaccggctt ttggacaatt ttacttcggc acatatctca aaaaagattt cattgtgaat
     7201 gtgtgtggac tttagaatat gattcaatgc ccattgtatt ctactgtctg taatagacga
     7261 aatatgataa tttaaattca atagacggaa agcttgtttt gaaaaatcaa tatagctttg
     7321 ggacaatcct tttacctgac aagctgtata aatattttgt attcgttcaa ctataagatt
     7381 atctataacg aaaaaagagt gatttagtaa ttggtgttga ctaatatttt gggcgagtat
     7441 gcttgtatca tctatcaaga aaaccaacat tttattatct ttacttgaca ccgtatgcga
     7501 tacattggaa tcaataataa ttcctttaca ttgtaatgat tcgcccttat caaacgtcac
     7561 agataagtta ccagactgtg atataataat atgttttgca agatgtttat ggatagttgg
     7621 ttgtctatac tctgtatcta aaaatatatg gtcaatcatt acacaaatgg tagtcatagc
     7681 tgtcaactcc ttgttcatag cttagcatat tatacagttt ttaacaagaa agcttagtga
     7741 ttacaagtat ttaaaaatcc tattttaggc aatgaaaaat aaaaaactct atcgagaatt
     7801 aaagtattta taaataacta tatttttact atgattcatg atagagtttt ttaaaattta
     7861 tgatactatt ttttattatt taaataatca agtgttttaa gtttataacc ttctttttcc
     7921 caatgtgtaa gaacctcatc taatatctca gtatttgttg atgaatttgg atgcagtaaa
     7981 actattgcac caggatgagt tcttgaataa attttgtttt tggcaaattc atgagtaggt
     8041 tgtttctttt cataccaatc tacataagca aaactccaaa atattgattt atatcctaaa
     8101 tcttgtgtat attttaaaga ttgttcgcta aatttaccca ttggaggtct aaaatactta
     8161 ggcatttctt ttccagtaac atctttgtat gctttttcta cacttgtaat ttcttctttg
     8221 aatttttcaa aatctgtaat acctgccatt gatggatggc tttttgaatg attacaaact
     8281 aaatgtcctt ctttttccat acgctttatt aactctggat tgctttttat ataactttca
     8341 actacgaaaa attgagcttt agcattgtgt tttttaagcg tatctaataa ttttggagtg
     8401 tttccacttt catatccagc atcaaatgat agatatataa ctttttcatt gggatttcct
     8461 acataataag ctccgtattt tttaaaaaaa tcagcttctt ttataggtga tggctgttta
     8521 ccatcctccc tagggttaaa ataccaatca tattcatgtg tgtcgagtgt tggactagaa
     8581 atttgagttt ttgttttatc taatgattta aaatttatac tagcaattcc aaaaagtatt
     8641 agagcaaatg ctcctatcat aatgtatttt tttaggctat cttttttcac aatttcacct
     8701 cttatttaaa atttaaagta tatttcttat aatatagttt gaatatttat agttaaaaat
     8761 attcacatat acaaataata aatgaaagaa gtttactgta agatataaag ttgatattaa
     8821 ttatcttaaa taaagtgtat ataaatgata aaatataaag agaaatgatt gtaaataagt
     8881 taggctggtt taacttgaag ggatataaaa atggataata taataagtgt attgaatgat
     8941 gttgtttttt tagatataga agttagtgga ttagattgtt taaattcaga aattttagaa
     9001 gttggagctg tcaaggttaa agactggaaa atatatacct atgaatcatt aataaaaaac
     9061 aaatttgagg tacctataga agtattctca gtatgtaaaa atttagataa aaatgattta
     9121 gaaatagcta atgaaataga actggtggaa gatagacttg taaattttgt agaagatagt
     9181 ttcattatat gtcatgattt aagtctgaaa aaaaagtttt ttgagtatca tatgccaaag
     9241 ttaaaaaaca aatttattga tttaattgaa ttagcagtta ttttagaacc atatcataaa
     9301 gattatagct tagaatactt aaaaaatact ttaacaaatt gtaattctaa agtggaaaat
     9361 agagctttat cagatgctat tgatataata aatattgtaa attgcctttt agtaaaattt
     9421 aataactatg aaaaaactac tttggagcca ttgagtttta aaataaattc atatcttaaa
     9481 aaatttaatc ttccaacatg ggaatggagc aaatttttag aagaggcaaa ttatgattta
     9541 tcaaataata taaatataaa aaaagaatat aatatatttg actcaaaaga agaaaagaag
     9601 aaggaaagag aaaccttaaa aattttaaat gaagaagaaa aaaattatga agaattatta
     9661 aaatacaaaa ctatttggga gaataaagaa ggatttacat atgaatatag acctggtcaa
     9721 tatgagctta ctaaaacaat aagagagttg tttagaaata gcgaagatga agaaaaaatt
     9781 gcatgtatag aggcaccaac tggtataggt aaaagtgtag gatatttatt gcctgcaata
     9841 ttagaggcta gaattaataa aaaaagatta ttaatttcta ctgacacaaa ggaattgcag
     9901 atacaattaa taaataaaga tattccaaat gtgttagatt ctttgggtct aaatggaaaa
     9961 gtaagttacg gatatataaa gggaaaaaat aactatattt gtatagatag actggaagca
    10021 tatatagatg attatgagtc tcaaaaccct actaaaggag aaattttatc tttaatattt
    10081 ttgaagagat tagttgaagg tggcaagtat ggagatatag aagaaataaa ttatttagtg
    10141 tttgacaact tcaaggaaat aagtacccac ttaagaaatg taagttgtga cccaaatatg
    10201 tgcagaccta aaaaatgcaa aaaagattgt ttatataaaa acagaataga agaattaaaa
    10261 gaagaacata taacagtagt aaatcattca ctattagcta aatggccgta taaggatgaa
    10321 aaacctttag aaaatataat agtagatgaa gcacataatt tgactgaaaa aggatatgat
    10381 ttcttttcaa gcattataaa ttcaaagtct ttaaggtatt tattacaaga aatttatcct
    10441 tacgagttta ttcaaaatag tagctttata tataaaaaat atagtagaaa tatgagaaaa
    10501 ataaaggctt ttgataaatt ttataatgta ttaaaaattg gaagagaaga taaacaaaaa
    10561 attgctagaa gtataaatct cattattgaa gagatagatt caatattaaa gtttggtaat
    10621 tgtaatgaat ataataatgt aagtaattat aatttaagat gggaactgaa tttgcaaata
    10681 gatgaaattg tgggaaaact aaaaaaggat ggtatagata ctgaaataag ttatagagcc
    10741 tatagtgaaa agataaagtt gagttgtgag aaaataataa aaaatttagt ttcaataata
    10801 ataataattt ataggaatat tgatgatgat agtatagata aagaagcaga tatatataaa
    10861 tttggaaagg caaagacaag agatttagag gatataaaga ttatatttga aatcttttta
    10921 gagtatgatg aaaaggatga ttatgcaagg atagttgaaa ttgataagaa ttataatgac
    10981 tttgaatttc gagtagtacc attaaaaata gcagatttat ttgaagaaaa tattttatct
    11041 caattagaaa aaggaatatt tttatcagca actttgagtt tatctgaaag tatgtcttat
    11101 tttaaaaata cattaggaat agacagagtt aagaatgtgg aaaagattat agaaccaatt
    11161 tttgattata aaaatagagt ctctgtagtt ggattttctg atatttgtga gtacagaaat
    11221 tctgaatttc caaatgagat gagtaaaatt atatctaata tatcaaagat tacagaaggt
    11281 catacattag ctctttttaa tagtaaagat agacaagaaa aaacttatga aatattgaaa
    11341 aaatacttac atagttttaa cttagaaatt tatgctgata aaaaggggat tagacacctt
    11401 aacgatttaa atagaaaatg tgtagtactt ggctcaaaag gatgttttga aggcgtagac
    11461 attccagggg atggtttggt ttgtgtaact ttagacaagc ttccgaatct aaatccaaaa
    11521 gaccctttgt attttactat aatgaagaag tatggtatag actactatac tataaattat
    11581 cctcaaatga ccataaaggt aaagcaagct atggggagaa ttttaagaag caaatatgac
    11641 tatggatgtt ttgtgatttt tgatgtagga actaatataa gtgttttaaa gagattagag
    11701 aaagatttac acgattgtaa aatttcaaag gttaatagca atgagtttta tacttatata
    11761 aggcgacatt taaataaatc tagaagttta atactaaaat ctgttatatt tgatactata
    11821 aaagcgttga atgttgatgc taaaatggat aacaatgatg ttgataaaga tattataaaa
    11881 aaagatataa atgaaaatat aagacaaaga gctgtaaaag gagaagtgta ccatattgat
    11941 attataaaaa aagatatgaa agtaaaatat tttgatagaa actatcttat aaatttagat
    12001 atatttatga gagaagaaga taaaaattaa gagtgggagt gagatatttg gcaaaacaaa
    12061 agttttatgc tgtgaaaaaa ggtaaaaata taggtgtata taatacatgg gatgagtgca
    12121 aaaaacaagt aaatggattc tcaggagctg aatataagag tttttctact tttcaagaag
    12181 ctaaagaata tattgatggg tcagaaaaat tgagttttca agaagataag gagtttatag
    12241 aagcatatgt agatggaagt tatgaacatt cagtaaaaat gtatggttcg ggtgttgtga
    12301 ttttaaaaaa taatgaagtt ataaaaactt atagtgaaaa aggaaaagag aaaactttag
    12361 taagtatgag aaatgtagct ggagagatag aggcttctaa aattgcaatg cagtactgta
    12421 ttgacaataa tgttcaaaac ttgattttat actttgacta tgaagggatt gaaaagtggt
    12481 gtactggagt ttggaaaaca aataaagaag gaactatagc atataaaaat ttctatgaca
    12541 gtattaagaa taagcttaat gtaaaattta caaaggttaa agctcattct ggaaataagt
    12601 ataatgagga agctgataaa ttagctaaaa aagctattgg tgtataataa aaaaatattt
    12661 atacataatt acatggtata agagtatatc taaattccta ctttataatt aaacaacttg
    12721 taattaaaca acttgtaatt aaacaactta taattaaata aattttgatt aaaaaagcag
    12781 attgtattat gaaaaaataa gtatctaatt tataaacaat taataatagt attaattaga
    12841 tacaacttat ttaatataat aaaatctgct ttttatataa ctataaaatc ttcctacatt
    12901 ctattagaat tgcccataaa taccttcaag ttcttctttt aatacttcag ggtcatttat
    12961 accaatagac atggttctag ccagtatatt tgcttggtca taagttgatg tccatgagaa
    13021 tacaccacct agacaatttc taagaacata ttgagttttt aagaatattg ataaagcatc
    13081 atcatatgac attgcaaaat ctccatcctt aactaaatac ggaacttgag cagtattatc
    13141 aaatctatat tcatatccat ttttatttat ataatccctt ctaagctcat cataagttct
    13201 tgttatagtg gcacctaatc ttccataaaa tggtataccg agaaggattt tttcagaagg
    13261 cattccagca ttctcaagat ttctcaccat tgcatcaaca ctatatcctg gcaaagataa
    13321 gtctgaatca aaaagatttg cttgatgttt tctaccattt gggcctgttt cacctgctgt
    13381 aaaatcataa ctcataagat taaaataatc tattatagga gctattttat ctatttcagc
    13441 acttgaattt atatatcctc tatctcctgt tccagctaca ctaagccatt tatcatctcc
    13501 tataacatct cttatggcag ttagtaagag tgtaaagttt tctctatctt gaggtcttga
    13561 tgttattcca gatgcactac ttccaggata ttcccagtct atatctattc catctaaagc
    13621 atattcattt atcatctgat tgacctgtct tgcaaaatta tatctagatg taggtgttaa
    13681 tgctgcatca gagaatcctt cagctcccca acctccaata gctacaatta cttttaagct
    13741 aggtttttca cctttaagag caagtaattg atttaaaaat ctaggataag gaataaacaa
    13801 atttccagac tggtctatct cagcaaaagc aaatataact gcatctaata gttgagcatc
    13861 tacattagtt ggatttccaa gaacatattc tgctacaatt ggatttatat ctggacagtt
    13921 tgcattttca actattggat tgtatgggtc tgttatttgt ggtctaacta atttttttga
    13981 atcttttaaa gttttcatag ctattttttt agtatttttt tcgctagtat aatcgtagtt
    14041 tttataatta tgtttataga aatcttcata actactatct tctttgttat agctagaatt
    14101 tattttgtcg caagattcat ctttatcata gttaaaattc atttcatcac aagacttatc
    14161 tttaaactta tcttgtttgg agttgtgaac tttgttagta tttttagtat gttttttctc
    14221 atggttgcaa tcatctttaa tatcagtctt gtgttcttgt ttacagtcaa gagctttgtt
    14281 caggtagtca tgatgttcat gttcacagtt acattcattt tcaatgtttt tagtatgttc
    14341 ttttttccag ctacaagtat tatcaatttt cttgctcact tcttcatcat tataattatc
    14401 tggtacaaaa cataagtacc agtccataca tgaatatttc ttattacaac tgttaactct
    14461 attttttaat tccttatagt ttttaggata aggtaaaatc actggcattc caggaaacca
    14521 gtttgcagga gtaactatat tatctctatc actagtctga agtgcatcta ctattctaag
    14581 tatttctgga atatttcttc ctgtagttag tggataataa agaatcgttc ttagaatttg
    14641 attattatct ataataaata cagagcgaac agttgatgta tcactcattg gttttgatat
    14701 catgccgtat aacttggcaa ttctcatatc tctatcttct ataataggaa atggaatttc
    14761 tacacctgta agtaaagaaa tattatacat ccaagctaaa tgtgaactgt tactatcaac
    14821 acttagacca attagttctg tatttctttt tttaaattcg tcataatatt tagcaaaaca
    14881 taaaaattct gtagtacaaa ctggtgtaaa atcaccagga tgtgaaaata aaacaatcca
    14941 attaccctta tagtcagaga gtctaatagg accatttgtt gtattggctt taaaatcagg
    15001 agcctttgac cctaaacttg gcaaatttgg catgtaaatc acccctcaat aaattatcat
    15061 ttattttatt ctattaatta atacatatta gtgttactat tttattaaaa gttaagtaat
    15121 ccttatgtca aaaaaagata tttattaaaa agatttaata ttttcctaat ataaatgaca
    15181 atagtaattg ctattttttt actaatttgg tatagtaatg gataaggggt agtgtcaatt
    15241 ttagtgatta tacgaggtga ttggattgaa aaaaattcta agaattttag ttatctccat
    15301 gatgatatgt tttgcaatga cttttgcatt agtgttaata aattcagtta tgggagtaca
    15361 tataggattg gattattact ttttgatggg aagtgtgctt acagtttgtt taacaattgg
    15421 aattgtttta tgcaatgcta gaaaaatatt tgatagcaaa gctatacaca agacaagaac
    15481 gaaaactgtc agtactaata aaaaacaaaa gagtcattct agggatataa aaagaaagat
    15541 atcataattt atgtaaagga aatatttatg tataaaataa tgattgatag gtaaaataaa
    15601 aacacgattt aacttgtgtt tttatttttt ttcaagaatt atgatataat aaccaataag
    15661 aaatttagtt taccataaaa tataaagatt attaaatgga gagggaacta taatgaattt
    15721 tagagattta tttgagaagg ctgtagattt tattgatgaa aaaaggaaat ctatagttgc
    15781 gatttcatta tcaacattag gtgtaattgc tttgataata gtatttttct taagtagtaa
    15841 cgagtttagt gtaggaaatg aagctaatga gttgttaaag attatagaga aaagacagta
    15901 ttctatagct gttgattact acacaagtat agaaaaaaag ttttctgatt caaaaatgga
    15961 aaggtttaat aagtctgttt ctaaaaaaat aaataaattg ctattaaata gtggtgataa
    16021 atatttagat ggagacataa gtcaagaaag ttttattgga ttaataaata ctgtgaaaga
    16081 attaaacaaa ataagtatag atgtggatga cttattagct caagctgata gagttagaga
    16141 aatgtataaa gaagaaaata ctacttatga tattgccatt aactacataa gtactgtttc
    16201 aatattaaat ggtatgggta gtaacctaga tgtatacaaa cagaatatag aaacaatcaa
    16261 agagtctaga gatgtttatg actcagcagt aaaagaccaa aaagcatata agtattatga
    16321 agctattgaa aagtataata aagtattaaa agaagatgaa aagtattaca gtatggctca
    16381 aaatgggaaa gaacaatgta ttgaagaaat gtatgattac tatataagta gagctgaaga
    16441 ggcaaatact tctggagatt atgaaagagc attacaatat attgagtatt taaaagaaga
    16501 ttattcagat gatgaaaagg tacagagttt agaaaaaaaa tataaaaaga atttatcatt
    16561 gtatacctta acatctgatg acattataaa tgtaatagct aaaaaaagtg gcaaagacaa
    16621 ggcaaatcta tctataaatt cacttccaca aatgataaaa aataataaat actattatgc
    16681 tgaagtatat gagtatgata aattaataaa tgaagttttg gtaagtgcaa aaactaaaga
    16741 tttatattcg tataaagatg gtaaaaaaga ttacaaagta gattatggtg atggatactt
    16801 tagaatatta gaagatggaa gttatcaatt tggtattaca aaagataaag ctaagtttgt
    16861 gttaactaat actcttgatg aaaaagaaaa taagtataaa aagattgaga tattagatat
    16921 agagaaagca gatagatatg taaaaagtaa aaagagttta gaagaattgt ttggaaaata
    16981 taaaaatatt tattattatg ctgtagtaaa taaaggctta tttagaggca aagaagttta
    17041 tgctattaat atttacaatg aaaaaatata tgccatatca gaaaatggac taaatgaata
    17101 ttaattaata atattaaatt aatatataat taaaaagttt ttggggtttt aaggcgcatt
    17161 atgtagtaat ataataatag ggatatataa ataattttat tgtaaggaga agtatgggat
    17221 gagtaatgtg aacaaaaagc tagttatagc tattggagct gtagcattag tagcaataat
    17281 ttttataggc ataatgtgca tgcaatttaa aggggagaaa atagcaaaaa acacatatgt
    17341 taatggagta gatattggaa aattaactaa atcgcaagca aaacaggaat tagctaaaaa
    17401 atacaaatta gagaatgttg agtttaatta caatgataaa agttggaaag taaagagcaa
    17461 agatttaaat ttatctactg atctggataa aacagtagaa aacgcatata atttaaatag
    17521 aaagagtagt ttctttggca atctatcaaa aactatttca acaaattttg gcaaaaaaag
    17581 caacttagta gttgtgataa attatgataa aaataaatta aaagcagaaa tggaaaaaat
    17641 agctaaagaa atagatgtag atgtaaaaga tgctacactt gatataagtg gtgaaaaagt
    17701 caaggttata ccagattctg atggtcttaa aatggatatt tctaagagta tggagaattt
    17761 tgataatcaa actaaaaaag gtaactataa aaatgagtta gtagtaaaag ctactccagc
    17821 aaaagtaaaa aaagagcaac ttactaatat agatacaaat ttaggtacgt attcaacaat
    17881 atttaaaact tctcaaataa atagaagtat aaacataaaa ttagcaacag ataatataag
    17941 taatgtatta cttatgccag gagaaacttt ctcatttaat aaacatacag ggaaaagaag
    18001 taaggaaaat ggatataaaa gtgcacctgt aataatggaa ggtgagatgg aagaagatta
    18061 tggtggagga gtttgtcaag tttcatctac gttatacaat tctgtgttat acgcaggttt
    18121 agaaattgtt aatgtaaaaa atcatactat accatcaagt tatgttccaa aaggaagaga
    18181 tgcaactgtt gcagatagtg gaatagattt cttatttaaa aataatctaa agcatccagt
    18241 ttacataaaa aattacgttt caggaaatca aattgtttgc aatatatatg gaagtgcaga
    18301 agataaacaa aatataacga tatcaacaaa attagatggc gtttcacaaa ctacaatgaa
    18361 aagagttaat gaccctacaa tgcctaaagg taaagaaaaa gtagacaaaa gtggaagaaa
    18421 tgcatattct gtatcaacat atagaacatt taatgatgca aatggtaaaa aaattaaaac
    18481 tgaaaaaata gctaattcat attatcctaa gaaggaaggt attatattag ttgggactat
    18541 ggaaccaaaa ccagaggaaa aaccaaatac agacgaaaat aagaataatc aaaatacaaa
    18601 caatcaaaat ccaaataatc aacaaaaacc agaaacacca ccaactgata ataagcctaa
    18661 tgagacacaa ccacaaccgc aagcttaaag ttctcaagaa taggatttat gtagagtaat
    18721 aaaaaatata aatctaaata ggagggatta ctttgaattt aaataatata acgaattacg
    18781 ttcaaagtat ttgcgagaat atttctaatg tattggatgt agatgttact ttagttacaa
    18841 aagatttaac taggatagca ggtacaggaa tattcagagg taaaatagga gagacaatat
    18901 cagagaagtc agtgtactct cttgttttaa aagatggaaa atcctatgtt ataaataagg
    18961 aaatagaaga gaactgtaat aaatgtgcaa atagagaaaa ttgtaaagaa ttagctgata
    19021 tatgtactcc tgttaaaatg ggagaacata tacttggaat cttgggtata gctgcgttta
    19081 atgaagagca aaaagaaaag atactttcaa aagataagga gttaactgct tttgtaagga
    19141 gtatgtctga tttaatatct tttaaactag atgaacttta taaacaagaa gttaagacta
    19201 tagatgacct tgagagggaa gctatagaaa atgccataaa gaaatatgga agtaatacag
    19261 aaggtatgaa aaaagtagct gaggcattaa atataggtat agctacactc tatagaaaag
    19321 taaaaaaatt caacattaaa agttaatagt attgaaaaag aggtaacctt tttatgaaaa
    19381 gaagaggatt acctttttta ttatgagaat ggtggaaaaa tatgtatagt tttgacttga
    19441 catattaaat atgttatctt aaatatatat tttagagtgg aggtgagtat tattttagtt
    19501 aaagatataa aacaagacat agaaagcatg cctagaaaaa ttttagatat atctttgata
    19561 gaagataata aaagtgattt gacttttttt aatatagaag aagaagacgg tgatgaaaca
    19621 ttaaaagcat taaaacagag ttatgtgact acaaattata aagaagaaac tctattaaac
    19681 ttgcaaggag ctttaaattc aaagtcagac acaacgtcta aggagttaaa attagaatca
    19741 tataaaagat ataacaatgc attggattta gcatataaaa attatataac tagtgccatt
    19801 aatatggtta ataaagctct ggagataaat cctaaagata ttgatatact aaatcttaga
    19861 ggtcttttaa agttattaaa atgtgatttt gctaaatcat ttgagagttt ttatactgct
    19921 ttatgttatg agaataatca tatatctaga aaatatgtaa atctaatttc atctgaagat
    19981 tttaaaactt ttttaggaag atacaatcat tctataagat ttataaatga agaattaaat
    20041 tatgagtcaa tacatatttt agagaacata attgaagaag agcctgagct aatagagcca
    20101 tatgtaatct tatctttgtt atatgataaa ctaggtaatg taaaaaagag agaaggatat
    20161 ttagacaaac ttaaagagct agataaagat aatcctgtat ttgaaaaaaa tgaagaagaa
    20221 aaagaagata caagtaaaaa ggaagaaata agaaaagtaa aaagaaagaa aagtatttta
    20281 ccatatatta tagttggctg tgttttaata ggtatgggga tatatttgat tcaaagcaaa
    20341 aagagaatag aaaacttgaa taaccaaata agtagtaaag aggaaaagtt aagtgaaact
    20401 gataaaaagt taggagaaac gagtaaaaaa ttagaaaaaa cgaataagga attaaatgag
    20461 gttaaaaata aagaaccaga aagagagata actgtagctg atgaggaaga tttatattat
    20521 caagctctaa atttaaagaa aaacaaagaa tatgaaaaag ccatagataa ttttaaaagt
    20581 gtagtttctt ctggtaaaac taaaaaatat atttctgagt caatatatca attagcaata
    20641 acaaataaat tattaggaaa taaggatgaa gctataaaat attacaaaaa atatataaat
    20701 acttatacta aaaatgacca gtattatgat gattcatatt acgagttggg tatgctttat
    20761 tatgataatg gcgatttaaa aaatgcacaa cagacttttt atagtttgag aagtgaagtt
    20821 ccagacagta tgtataacaa ttcaaaaata aaagaaatct taagtgaaaa ataggtttat
    20881 atagttaagt tttttgaaac aaccaagtat gtattttatt aaattaaaat aaaaataaat
    20941 ttaaaaagag attgtgtcaa attataactt tctattttaa agaaagatat ttgcttgttg
    21001 ataaaactac aaatatatga tttgaagcaa tctctttaat ttttggaggt ggaaaatgaa
    21061 agttttcaat caattagtaa taattttatc tatctgggta ataggagagt atataagttc
    21121 ctttatacaa ggaattatac ttattcctgg gagtatagtt ggtatgctat tattatttct
    21181 actactacaa tttaaagttt tagacttgag tagtatagaa aatgtaagtg gatttttcct
    21241 cgataatatg gctatatttt ttattccagc aggtgtatca cttataaagt cattagacct
    21301 aataagggaa aatgtattag tgcttttatt agtcatatgt ttaagtacac taatagtaat
    21361 gtatactact ggaattattg tggagaaaat gataaaaaag aaggaagaag gacaaaaaaa
    21421 tgtataatgt attacagaca ccagtatttg gtataatagt aacaatagtt tttttcaatt
    21481 taggaagata cattcaacga aaaacaagta atcctatatg taacccttta ttaattgcaa
    21541 tcgtaggaat aatattgttt ttaagcatat ctaaaatccc ttatgagaat tacaagatag
    21601 gagctgatag tctaaatttc tttttaggtc ctgtcacagt agtacttgca gttccacttt
    21661 ataaacaatt tgaattattt aaaaagcata tgtttgagat tattgtagga ataggttgtg
    21721 gtatagtgat ttcttttgta tctgtattga taattggcaa aatagctaat tcagatgtaa
    21781 gtataataaa ttcactaatt ccaaaatcta taacaacacc aatgggaata tctttagcaa
    21841 attctttaaa tggtatagaa tcaataacag ttgtagccat aatttttaca ggtatttttg
    21901 gtggtatggt tgcttctaca gtattcaaac tggggaatat aaatcatcca gttgctaaag
    21961 gaattgctct tggaacatct gcacatgctt taggaactac aaaagctttt gaacttggag
    22021 aaatagaagg agctatgagt ggtgtttcta ttggagtttc tggtacaatt acagtaatac
    22081 taattccaat tataatgaat tttatataaa aaataaaatt aagacgagta ccttgaatac
    22141 ttaaaacaaa ataaaataaa aaaaatttaa aataaaaact gaacgaaaaa aatgcaaata
    22201 atgaaataaa aaaatcatgt actgaaatta taaaaagaaa aatttcattt aggaattaat
    22261 tataaagaga taattactaa acttgaattt gctaaaataa aataaattac tgcgaaaata
    22321 gatatttaga aaaaaatact ataaatttac tatattgcaa gttaaataat aagcagtatc
    22381 atattatgct agaaaaagtt tcatttaagg cataaatgag atgatttgaa cgtttttaaa
    22441 gattagaata taaaagattg cactagacat atatgaaaaa gataatataa tagatgatgt
    22501 aatagatgac agttcaagaa attataaaaa aaatttattt gaaatattat ctattacatc
    22561 aggaataata tatgtaagag taagctttta aaattctaaa gatttagaaa gattgaaggg
    22621 agaaagaaat gagtgaagtt aagaataccc tacaaaaaca tccagtttta agatattcaa
    22681 caatgctatt tgggatgttg atgacatcta taggaataaa tgggttctta agaccagcac
    22741 atctgcttag tggaggtgct acaggtatag caacatctat aaactatttg acaaatataa
    22801 atgtaggttt attaacattt ttaatcaata ttccaatatt tatcttaggg ttcatatacc
    22861 ttgaaaaaga gttttgtatt tcaagtttgg taaatatgat tgtattttca ttattattag
    22921 gagcaactca ggaaataagt aatattatac ctatacatga tatattgctt caaagtgtat
    22981 atggtggtat attatctggt ttaggagtcg gagttgtatt tagaactagg tcttctcaag
    23041 gtggtacaga tataatagct gcaatactaa aaattaagaa gaatatagaa atgaaagaca
    23101 ctgctttagc aataaatggc ttgatagtac ttacaggaag ttttttattt gggttggatt
    23161 tagcattata cactcttata ggtctatttc taaatgcgta ttcaatgagt tttattaaag
    23221 atgcaatgaa ttaccaaaaa tctgttatgg taatgtcaaa tgaagtcgat ttaatagcag
    23281 aagatataat gaagagttta gttagaggtg taactttttt agatgcagaa ggtgcataca
    23341 ctcatcaaaa aaagaagatt atatatacaa tagtttcatc aaatgagata ccaaagataa
    23401 aagatatagc tttgaagtat gataaaaagg cctttatatc tgtaaatgat gttacagaag
    23461 taaaaggaag agggtttaaa gcaaaagatt tatagaaaat tttacaagct gggagtttat
    23521 aatgtaaatt tgtatattat atctctcagc ttatttaaat ttagtatatg aaaataaagg
    23581 ttttatcaat gatttgtgta tcactttaaa agatatcatt ttaaaattaa aattgaaaaa
    23641 attactcaat atgtagaaaa cataaccact attaggatat aataaattta atagatttag
    23701 taaaatatct aggaataacg ttggaggaat agcattatga atttatctaa agaatatgtt
    23761 aatttgtatg ataattattt gaaatatata aatgaagtaa acaaagagat tagaagtata
    23821 aagaacatga agaaacgtgt tttaaaaaag ggcgattttg ctccagaaaa tgaagtatta
    23881 gaattggaag gaaaaacaat acgcgatata gatgatgtcg atacaaaaaa accaaaaaat
    23941 aaaatatata aattttcaaa tggggatgtg tatgtaggaa aatttttaga aggaaagatg
    24001 gaagggcaag gatcatatac tttttttgtt gatgaaggaa cggctatgga gtacatagga
    24061 gagtttaaag aagacaaaaa aaacggaaaa ggaaactttg tattttcaaa tggaaatgaa
    24121 tatataggcc attttgagga agatatgatg aacggtattg gaaatatgtt atataatagc
    24181 aaagatgaat atattggaac ttggaaaaat ggaaaaaaag atggaaaagg tatttataag
    24241 tggagtgatg gatgtatata tgcaggtgaa tttaaaggtg gaaagatgga agggtatggt
    24301 atttgctata atagtaaagg ggaagtactt tatgaaggag aatggaagaa taatttgatt
    24361 catggtaaag gaacttatat atgggaaaaa ggtaaaaagt atataggtga atttatgcat
    24421 ggtaaaaaac atggacaagg aactttttat ctaaataatg aattggttta tgaagggact
    24481 tggaaatttg ataagccatc catcttcgac agaacattag atgaaatatt ttcattaaga
    24541 ctatagcttt atctattaat agataaagct tttttctaat acttactgta aataagtatg
    24601 aatgatattg attagtatac actatcaata ttaactcaat aaatgtgata ttaaaaattt
    24661 ttgattgatt ttaagaagga gggatatatt gaagagatta attgctttag tgttagtaat
    24721 acttattgtt ttattttata gccctgaatt gatagaagaa ggatatgatt taaaagaaaa
    24781 attttttcaa agtgaaatat ggaatgaatt tttagacaaa ataaatataa ataataattc
    24841 taagaaagat aaaaaagaac aaaatcaaaa tttacaatca aataatactg aaggggagaa
    24901 cttaggagag tcagatataa agaattttga aaaaataagc ttaggagata atttaagcta
    24961 tgttttatca agtattggta aacctggtag aattgatatt agtgaatatg gttttgattg
    25021 gtatgtatat aatcaatatg gaaaagaatt tgcaatggtc ggacttgaaa atgatgaagt
    25081 agtagcactt tatagtaatt ctattaattc atgtgaaaat caagatataa aactaaatca
    25141 agatagacaa acagtgagaa ctaagattac accattaaaa tataagagaa aaggaaatac
    25201 cagatatata ataaactcag aaaatcaata tgatataata agtaaagaag gtaagtatat
    25261 tacaattttc tacgatattc atgaagaaaa tagagtttgc tcatatttaa taattgataa
    25321 aagtactgaa gatgagttta aaaaattata tccagatgat agagaagaac ttaaaaaatg
    25381 ttttgaactt gaagttatag accttgtaaa tagtgttaga aatcaaagag gattaaactc
    25441 attgagatac agtgaacagg caactttgag ttcaagaaaa catagtgaag atatgagaga
    25501 taataatttt tttgaccata taaataagaa gaatgaaact ccatttgaca gaatgaaaag
    25561 agaaggtata gtatatactt cagctggaga aaacatagca gcaggacaga ttaatgcaat
    25621 atatgcgcat gaagcttgga tgaactctga aggacataga aaaaatattt tggggaacta
    25681 taataatatt ggagttggag taatatttgg aggaagctat aaaacatatt acactcaaaa
    25741 tttttataaa taactaaaat atttgaaagg aagttaaaaa atgacatcat ggaaaaaaaa
    25801 gacagtatat aagtgcttaa tagcagtagt cttgttttgt ggaatagtgt taatatctaa
    25861 ttttagtaaa gtttctgctt tgatgatgga tactaatgga aatgttttga ttaaacatgg
    25921 ttcaagggaa aaaaagctaa tagcaattac ctttgatgat ggtcctcatc ctaaagaaac
    25981 tagtcaagtt ttagatgtat taaagaaata caatgtaaaa gctacttttt ttatagctgg
    26041 aaaacatgca aaatggtata aagaaccatt agtaagagca agtaaagaag gtcacgagat
    26101 aggaaatcat actttcaatc atcctgatat aagtaattta agttctagtc agatagaaga
    26161 ggagattgtt aagtgtgaag acattttgaa agaagtaact ggaaaaaaac ctacattatt
    26221 tagaccacca tttggaagtt atagagaaaa agacttaata gaaattgcaa aaaagcatga
    26281 ctataaagtt gttttatgga caggtgtaga tgtgaaagat tggaaaaatc caggagctaa
    26341 tagcattgca gataaaataa ttaataaagt aaaaaatgga gatataatac ttttgcatga
    26401 ttatgcaact aatgatacag ttgaagcttt agatatgttt attccaaaaa tgattgaaaa
    26461 aggttttaaa tttgtaacag tttctgagtt gataaaataa tttttagggg ggagatttac
    26521 agtatgattc ttatgataga caattatgat tcttttgtat acaacctagt ccaatatata
    26581 gaagaattag gggaagcagt tgtagtaaaa agaaataatg aaatcaaaat aagtgacatt
    26641 gaagaactaa atccagaggt aattgtgtta tctccaggac cgtgttctcc aaaagaagct
    26701 ggtatttgca tagatattgt tgagcatttt aaggggaaaa aacctatact aggaatttgt
    26761 ttaggtcacc aaactattgg atatgttttt ggaggagata ttataaaagc acaacagcct
    26821 gtgcatggaa aagtatatag tatcaaccat actaataaag gagtttttag gggacttaaa
    26881 aatcctttaa atgtcactag gtatcattca ctaataattg attccaatac agttccaaaa
    26941 gaattagaaa ttacagcaat tactgataaa ggggaaataa tggggattag gcataagaaa
    27001 tatttaatag aaggagtaca gtttcatcca gaagctattt tgtcagagta tggtcatgaa
    27061 atgcttgaaa attttataac agaagctaga gaaagggtac atatgtaata tgataagaga
    27121 gataaatact aaattaaatt cttttgagat atttactatt tttagaaatg aacatgacag
    27181 ttttatatta gacagtgcta tggataaaga aaaattggga agatattctt ttataagtag
    27241 ccaaccattt aaggtattaa agtataagga tactgatgaa aatcctttag aagttttaaa
    27301 agaagaacta cataagtata gggttgtaaa tgatactaat cttccatttg taggaggtgc
    27361 tgtgggatat ttatcttatg atttaggtaa ttacatagaa aatttaccta gaactgctgt
    27421 agatgatatt gagatgcctg atatgtattt tggattttat aatcatgtaa tagttataga
    27481 ccatcttgtg caaaaaactt atatagctac tccaaacata gatatcgaat tagaagaaaa
    27541 gataatagat gatatagaac aaagaatatt aaaagaagag aaaaaaggta tagatagcat
    27601 atgttatgaa gaaaaagaag taacacctat aagacttaaa tctaatttta caaaggaaga
    27661 atttaaaaat gcagttcaaa gtgttagaga gtacataaga caaggagata tatatcaagc
    27721 taatttaaca caaaggttca gtggagaaac agaacttaca agctttgaat tgtataggga
    27781 cttaagaaga tttagcccag caccatttgg ggcattctta aactttgaag atacacatat
    27841 attatcaaat tctccagaaa gatttataag atgtgttaat aagagaatag aaactagacc
    27901 aataaaaggt actcgtccaa gagggaaaga taaagaagaa gatttaagac ttcaacaaga
    27961 acttagaaat agtgaaaaag atagagctga actacttatg atagtagatt tagaaagaaa
    28021 tgatattggc agaatatcta aaactggaag tgttaaagtt ccagagctat ttgtaattga
    28081 accatatgca aatgtaaatc acttagtttc cacagttgta ggtgagttaa aagatgataa
    28141 agatgctact gatgtaataa aagcaacttt tccagggggg tctataacag gagcacctaa
    28201 gattagagca atggaaatta tagacgaatt agagccaacg caaagaaatg tatatactgg
    28261 ttcaataggt tatataggtt ttaatggtga tatggatttt aatatagcaa ttagaacaat
    28321 aatcaaaaat gacaaaaaag tctattttca agttggagga ggaatgactt gggattctga
    28381 cccagatgaa gaatatcaag aaacacttga taaagctaaa tccataatga aggctttgag
    28441 gggatattat gaagaataat gtaggttttg atagtagttt aagtaaattt ggaattggtt
    28501 tgtttgaaac tattagagtt aaaaatggaa tagcagtaga tttagatatc catatagaaa
    28561 gaatgctaag ttcaataaat tgtttggatt tagatataaa ctataaaaaa gatttcttga
    28621 taaatgaaat tgttacatat ataaaaaaag aaaatgtcat taataaagca cttagaatta
    28681 ctgtttttga tgaaggttat aatatatcta ttagggatat tccatataat caagagacgt
    28741 atgagaaggg gtttaaatta gctatatcgc caatagttag ggggaatagt ttaattcata
    28801 gacataagac tactaattat tttgaaaaca tatataccaa aaatatcgca aataagactg
    28861 gttataatga tggtatattt ttaaattcag aaggtgtaat attagaatgt tctatgagca
    28921 atattttctt tataaaagga gaaagagtgt acactcctag tgatagatta ccgatattaa
    28981 atggaataat aaaaaaaagg attatagaga tttgtgacga attacatata gagttgatag
    29041 aaaatgaaat taatatatca gaaattagta gttttgattt tgtttttgtc acaaatagtc
    29101 ttatgggcgc tataaaggtt acagaaattg acaaaataaa atttaataaa gaaaatgttg
    29161 tttttgataa aatagtgaag ttattagaat aaattaaaat attaacaatt tgttggagac
    29221 aaaagatgat aggttgtatt tatgaagtat acaatgaaga gatgactaaa ataatagaaa
    29281 accaaaacac tttggctgta tatttagtag gttctagtaa agacgtagat tttactcttt
    29341 atgatgtaga gataaacgat attgatgtgt tcgtttttgt aaaagaaggg gaaaaacaag
    29401 agagaatact gtttaaaaaa aagggaatag aatttgatgt aaattacttt tcaaaagatg
    29461 gtgtaaaaaa attattatca aatagggaat atttctttgt gaaagaaatg aaagatgcta
    29521 aagtactgtt tgatagggag aatatatcaa atattataaa agatataagt agagatattt
    29581 acttagaagg acccagtaaa atgtcattag aggaaaagtc ttttataaag caagatattg
    29641 gagcaaaaat atcgaattta aaaaataaag aaaaatttga tgtttttgaa tatcattttt
    29701 tgacgaattt atatttaaaa gatataataa ttgggtactt taatataaat gataaatggg
    29761 taccaaaaga caaaaaattg ctaaaagttt taaaaaaaga aaataatgag ctttttgaac
    29821 tagcgtcaaa agtaagtgaa aattatgact atcaaagact tttagatgtt tataattata
    29881 tttttaaaga aattgagaca aaagaggtta taaaactaat cttctagtca caaatcaatg
    29941 gggggagttt aaatgaataa agttgataaa gaaaagatac aacatgcagt aagagaaata
    30001 ctagaggcaa ttggagaaga cccagataga gaaggtctaa tcgagactcc aaatagagtt
    30061 gctaggatgt atgaagagat attctctggt cttagtgaag aaccaagaga ccatttaaaa
    30121 gttctttttg cagatgaaaa acatgaagaa ttagtattgg taaaagatat tccattttat
    30181 tcatgttgtg agcatcatct agttcctttc tttggaaaag ctcatattgc ttatttacca
    30241 aaaggaggaa gacttacagg gctttctaaa cttgctagag taatagatac attggcaaaa
    30301 agaccacaat tacaagaaag aatcactaaa aatgctgcag atataataat ggaagaatta
    30361 caaccttatg gtgtcttagt agtagtagaa gctgaacata tgtgtatgac aatgagaggt
    30421 gtaaaaaaac caggttcaaa aactgttaca tcagcagtga gaggaatatt tgaaaaggac
    30481 attgcgtcta gagccgaggc tatgagtttg attactatga agtagcaatt tattatagat
    30541 ataatcattt attgagatat aaaatttaat ttaagggagt gtcattaatt gtgtttgatt
    30601 atggtaaaag aacttatata atgggaatat taaatgtaac tccagatagt ttttctgatg
    30661 gaggagattt taataacttg gacatagcaa tacaacatgc aaaagatatg gttgaccaag
    30721 gtgcagatat aatagactta ggaggagagt ctacacgccc aggtcatagc tatgtagact
    30781 cagacgaaga gctaagaaga gtaatccctg taataaaaaa acttaaacag gaattggaga
    30841 taccaatatc aatagacact tataaggcag atgttgcaga agaagcatta aaattaggtg
    30901 tcactatggt aaatgatgtt tggggtctta gaaaagataa aaatatggct tctgtaatag
    30961 gaaaatatga tgcagaagtg tgtataatgc ataatcaaga tgggacaaac tatgacaaag
    31021 atataatgga gtcaataaaa gactttttta aggtaagtat agaaatggca atgagttgtg
    31081 gtgtaaaaaa agaaaaaata gtacttgacc caggcgtagg atttggcaag gattttgaac
    31141 aaaatattga agtattgaga agattaaatg aattaaaaga tttagggtat cctattttgc
    31201 ttgggacatc cagaaaatca gtaataggaa aagtacttcc agttgagcct aaaaaaagat
    31261 tagaaggtac aatagctact actgttcttg gtataagaga tggcgtagat atagttagag
    31321 tacatgatgt ttatgaaaat ttaatggcag ctagaatgac tgatgcaata tatagaaagt
    31381 aggtataata taatggataa aatattactt agtaatctag gattctatgg atatcatggt
    31441 gttcttaaag aagaaaattt tctaggtcag aaattctttg tcgacatgga actttatatt
    31501 gattcaagag aagcaggtct tagtgacgat ataaataaat ctgtaagcta tgccgaggtt
    31561 tacaatgttg ttaaagatat tactgaaaat aaacaattta atcttttgga ggctttagcg
    31621 gaaaatattg ctgaagaagt cttgaataaa tttatactta taaatggagt tatggtcaga
    31681 gttagaaagc ctgaggctcc tgtaaatggt atttatgact attttggtgt tgagataagg
    31741 agaacaagag atgaataagg cttatttggg aataggtact aacatgggtg atagatttga
    31801 taatttatca agagcatgtg aacttttgaa aaatagtgat tctatatata aagtaaagga
    31861 atcaagttta tatgaaacaa aaccatgggg atatacagaa caagcagatt ttctaaatat
    31921 gtgtgtagaa atagaaacag aatttgaacc ttatgagttg ttagaatatt gtcaagaaat
    31981 agagagagaa ctacacagag agagaatagt tcattgggga ccaagaacta tagatgtaga
    32041 catactattt tttaatgatg tagcttccac tgatgaaaga ctaacaatac ctcatccgag
    32101 gattcaagat agagctttcg ttttgatacc acttatggat ttaaatgaag aacttataat
    32161 aaatgaaaaa acagtaaaag aacatttaaa cctcctatct gctgaagaaa gagaagaagt
    32221 aaaggagctt gtaggttatg aaagaaaacc tatttaataa taattcaaag atagagataa
    32281 atacaaataa caaaaagata actgtaaaaa aagataaact tataatagct ggaccatgtg
    32341 caatagagag ttatgagcaa cttttggaga ctgctaaatt tgtaaaaagt cagggagcaa
    32401 atattttaag aggaggagcg tacaagccaa gaacatcgcc aaattcattt caaggattaa
    32461 aaaaagaagg tcttaaaata ttaaaagcag ttaaagacga agttggtatg gctgttatta
    32521 cagaacttat ggatgtaaga gatatcgacg aactgtatag tataagtgat ataattcaaa
    32581 ttggttcaag aaatatgcaa aactttactc ttttaagtga agtgggaaaa caaaataaac
    32641 ctgttatgtt aaaaagagga atagcatcca caattactga atggataggt gcttctgaat
    32701 atatagcaat agaaggaaat agtaacatta taatgtgtga gagaggtata agaacgtaca
    32761 atgattatac tagaaataca ttagatttag ctgcggtacc cattattcaa aaggaaacag
    32821 gtcttcctgt tgtggtagac ccaagtcatg ccactggagt tagatatttg gtaaaaccta
    32881 tgtcactggc atcttttgca tgtggagcag atggaataat ggtagaagta catcctgacc
    32941 cagaaaatgc tttgtcagat ggtgctcaat ctctttgttt taatgaattt gaagatttaa
    33001 tgaaatcaat taataattat taaaagaggc aagagcctct tttttattcg taatcattgc
    33061 taaggtaaat ttataagtta taatttgata gttagattat ttaatataaa taaagattta
    33121 atattgatag aattaatata aaaaataaaa attttttgat taataagaag gatatcaata
    33181 aaaaaagtcg aattgtgtat attgagtgat tgacaaattt agaatatagt gtagaataga
    33241 aatgttaaca caaaaaatta caccagaagg tgataatatg aatgatataa aagacattat
    33301 tgaagaaata aaagctagat gcgatatagc aagtataata tctgaatata tgaatataaa
    33361 acaatctgga gctaattaca aagggttatg tccatttcat ggtgaaaaga caccttcttt
    33421 ttatataaat acatcaaaac agatttataa gtgttttggt tgtggtgaag gtggagacgt
    33481 aataaatttt gtcatgaaaa tggaaaattt ggattttatg gatgctgtaa aaattttagc
    33541 aaataaatgc ggtatagaaa ttaacactaa catgaatgaa gaaactagga ttaaaataga
    33601 aaaatctaag aaatttcaag atatccatac ggaagcagct agattttatc tttcaaactt
    33661 attgggaagc aaaaatcttg ggtatgaata tttaagaata agaggactag atgataaaat
    33721 tattaagaaa tttggtttag gattttcttt ggattcatgg aattcactta tgaatactct
    33781 aataagtaaa ggatacaaaa aacaagactt attggattgc ggtctaattg caaaaaatag
    33841 agatggaact aattgctatg ataaatttag aaatagagtt atgtttccta tatttgacta
    33901 tagaggaaac ataataggat ttgggggaag agtattagat gattctttgc caaaatactt
    33961 aaattctcca gacacattaa tttttaataa aaaacagaac ttatacggat taaattttgc
    34021 tagaaaaaat ttagaaagta aaactatagt cttagttgaa ggatatatgg atttaatttc
    34081 gctttatcag tatggtataa aaaatgtagt agcaaccctt ggaacagcct tgactgaaca
    34141 acaaggcatt ttaataaaga gatatgcgga cactgctatt atatcttatg attctgatga
    34201 agcaggaata aaagcgactt taagagctat agatatactt actaaattag gtatcaatgt
    34261 aaaagtgtta gacttaaaag atgctaaaga cccagatgaa tttgtaagaa aatacggact
    34321 tagtgattat aaaaaagcta tggatgtttc tactcactac ataaaatata aaatagatca
    34381 tcttaaaaaa gaatttaaca ttcaaaaaga tgaagaacga gtgaagttcg caaaagaagc
    34441 ttctaaaatt ataaaacaat tgacaagtcc tgttgaaatt gatttttata caaagtattt
    34501 aagcaatcaa atagatatta atgtcgagtc tataaagaga gaagtttatg gcaaaaatta
    34561 caataagcca tataataaca aaaatcaaaa gaaaatagaa gaaaaagtaa ttgaaaaagt
    34621 cgaagtcaga caagacggaa aacaattagt tgaagaaact ctaataaaaa taatgttaga
    34681 agacaaaaaa attagagaaa tagcgttact taaagtagaa gaaagtgatt ttttattgaa
    34741 agaaagtaaa gaaattttaa attacatgat taaaaatcaa gaattggaca aaataactat
    34801 tgacaaattg aaaagtttaa acatatccga agaatactta aaagaattaa attcaatttc
    34861 tttgaatagt ataaacttag agaacacaaa agaaatagaa ggaataataa caaatatcag
    34921 aaaaaactca ttagaagagc aaattaatag cttgttgaga gaacaacaag aattagaaaa
    34981 taataatgat atgaaagagg tagatggtag agttatggaa attgctttaa aaatagttga
    35041 gataaataaa attttaaaga gcttgtagag aaaggaggtt tgagtgtgga aaataaatcg
    35101 aataaaaaag agttaaaaaa ggttactgct aagacattaa tagaaaaagg aaaaaagcaa
    35161 ggttctctga cacttgcaga gataatggaa gctttttcgg agactgaact tgataaggat
    35221 caagtagaaa atctttatga gactttagga aatttgggaa tagaaataac agaaacaaaa
    35281 aattataaag ctgatataga tttttcggtt gctgatgacg atttaagtat aggccactta
    35341 gatgaagatg cagaggcaat ttcacatgat gactcttctg caatagaaat agaaactgtg
    35401 gatttatctt taccaaaagg gataagtata gatgaccctg taagaatgta cttaaaagaa
    35461 ataggaaaaa ttcctctact taaaccacat gaagaagtag aatttgctag aaggatgcac
    35521 gaaggtgatg agatagcaaa acaaaggtta gttgaagcaa acttaagact agttgtaagt
    35581 atagcaaaaa gatatgtagg aagaggtatg cttttcttgg atttaataca agagggaaat
    35641 ttaggtctta taaaagcagt cgaaaaattt gactatacaa aaggatataa gtttagtact
    35701 tatgcaacat ggtggataag acaagctata acacgtgcta ttgcagacca agctagaact
    35761 ataagaatac cagttcatat ggtagagact ataaataagc taataagagt atcaagacaa
    35821 ctacttcaag aacttggaag agatccaaaa ccagaagaaa ttgcaaaaga aatggaaatg
    35881 acagaagata aagtaagaga aataatgaaa atagctcaag accctgtgtc tttagaaaca
    35941 ccaataggag aagaagaaga tagccattta ggtgatttta ttccagatga tgatgctcca
    36001 gccccagcag aggcagcagc atattcttta ttaaaagaac aaatagaaga tgtacttggt
    36061 tcgttaaatg atagagaaca aaaagtatta aagcttagat ttggtcttga ggatggtaga
    36121 gccagaactc ttgaggaagt tggaaaagag tttgatgtaa ctagagagag aataagacag
    36181 atagaagcaa aagcactaag aaaactaaga catccaagta gatcaaaaaa acttagagat
    36241 tatttagact aaaaagatac atcattgatg tttttgtgat aaatgccatg agataagtga
    36301 tatctcatgg ctattttgta gtaaagattt aattttattt ttgtagttat ttcagtctaa
    36361 tatctataac ttggattaaa tcctataaat aaagggaatt gaaaggagaa ttatatttga
    36421 aattaacaga tagattattg aaaatagcat cattagtgtc agatggtaaa aaaatagctg
    36481 atatagggac ggaccacgga tacataccag tatatttgtt aaaagaggga aaagtaccat
    36541 ttgcagtgct agcagatgtt aataaaggac ctcttgacaa tgcacataaa gaagtcatac
    36601 agaacaatct tttagataaa gttgatttac gattgggttc tggtatagag atacttgaaa
    36661 taggggaagt agaagaagtg ataattgctg gtatgggtgg aatcttgata agtgagcttc
    36721 tcgaggctaa aaaagaagta gcacataatg tagaaaaatt aatattacag ccaatgcaag
    36781 cacaagaaga acttagatat taccttttaa acaacggata tgaaatttta gaagaagttt
    36841 tagtgagaga agattttaga atatatgaga taattgttgc caaatataca ggtaaaaata
    36901 ctataataga agatgagata tattatgagg ttggaataaa gcttttagaa aacaaagatt
    36961 ctctttttaa tgattttata gaaaaaaaga taaagacata tagttctata gttaataaat
    37021 tagaagggaa aaatggggaa gctatagata agaagagaaa ggaaagcgaa gttgcaataa
    37081 aaaaacttga aaatttaata aaataaatag gaggtatata tgctattaaa gagtctaact
    37141 agaaaaattg aaaaaaagta tcctctaaac ttagcagagg attgggataa tgtaggtctt
    37201 atagttggag attttgatat ggatgtaaaa aaggtattgg tatctttaga agctaatgaa
    37261 gatgttattg atgaagctat atccaaaaat atagatttaa ttgtgacaca tcatcctttt
    37321 atatttggga aaattaataa aattaatagt ggagatttaa aaggcagact tatccaaaaa
    37381 cttattaaaa atgatatatc actttattct atgcatacga attttgatat agcatttgat
    37441 ggtctaaatg actattttat ggaaattatg gaatttggta attcaaaggt tttagatata
    37501 actaaaagcg aaaatttgta taaattagca gtatacgttc cacataacta ttcagatgaa
    37561 cttagaaagg ttttaagtaa ttcaggagca ggtcatatag ggaattatag tgattgtacg
    37621 ttttcaatag aaggtgaagg acaatttaag ccattagaag gctctaatcc gtttcttgga
    37681 agtgtaaatg atatagaaac tgtaaatgaa gttaaaattg aaactgtagt accacagaag
    37741 cttttaggtg gggtaataag ttctatgtta gatgcacatc cttatgaaga agttgcatat
    37801 gatttgtaca agttagaaaa taaaggtgag atatttggac taggtagaat aagtaaactt
    37861 gataaaagta tgacattaga aagtctttca aggaaaataa aagagaaatt aaatatgaaa
    37921 cacataagag tagttggaaa ccttagtaca gacataacga aagtagccgt tgtaacagga
    37981 gctggttcag aatttgtaaa aaaagctaag agacaaggtg cagaagtact aattacgggt
    38041 gatgtaaagt atcatgaggc acaagatgca cttgatattg gaatgtgtat agtggattgt
    38101 ggtcattttg atacagaaga tatattcaaa aatgttatga agagattttt agatgaattt
    38161 agtgaaattg aagtaataaa gagtaatgta tatttgaatc catttagtac tatttagaag
    38221 tgtttgatta aaaaatacta tataaaaaat aaatttgagt ttaattaggg ggataatgat
    38281 gaaagtagca gtaatttttc atagtgtttg tgggagtaca tatttattag ctagagaata
    38341 taaagaagtg cttgaagaaa tgaatatcga ggtagatata tttagagtaa gtgacgaagt
    38401 tgcaaaaaca cttcctcaat attatttgat aaattacaaa gaatacaaag acgaatttga
    38461 aagtataaat gtaattaaat ctggaaaaga aatattagat tatgatgcta tatttatggg
    38521 ttcaccaaca tattatggaa atgtatctgg accaatgaag atgtttatgg atagtttttc
    38581 tgatatttgg gtaggtgctc ctttgagtgg taaaatattt ggttgttttg ctacagcagg
    38641 ttcacaacat ggaggaggag aattagcttt gcaagctatg aatatatttg ctcaacatat
    38701 gggaatgact cttttgtcag ttccatgttc agtaagagga ggttatccag cgtatggaat
    38761 acttcatata gcaggagata attctgatat aagaccaaat gatgatgcca agataggtat
    38821 aagagattac ctaaaaagac ttaacatata agaatatcat ataaaaatac ctaaaagtag
    38881 ctgtatatac ttttaggtat ttttacttaa ttatatacgt gaagctttac cagaaatatg
    38941 gtcaatttct attttaacaa cagttgttaa gttcatatcc ttctctatgt acttcatgcc
    39001 ttcttcaaag aatcctttag aatatttttt tattatttct acaagagcat ttttcttttc
    39061 ttcattttct acagtgcaag cttttccaaa aactatagca ctagaataag tagtactaaa
    39121 tttatctgga ataacacttt cattagcaac tactaaaaaa gaaactttgt tgtttttcga
    39181 tatattatct aacttatgtc catttcttgc acaatgaaag taaatagaat cattaaagta
    39241 tacataattt acagcaactc cataaggata accattttca gatatagtgg aaaaagtacc
    39301 aaattcacca ttttttaata cttcaacagt atcttctttt gtcatttctc tttttttcaa
    39361 tctcatttct ttaaacataa tatcatcctt tctaattttg atgcttaaat taaattttag
    39421 cacatttata aagattatgc tatgtttttt acaaatttta agaaaaaaat atagtttaag
    39481 ataaaaggta gtgaaagaga agctatttgg aggtttattt atgatattat tgttagagta
    39541 gtacaaacaa tactaataaa tttaatagct ggtttcttgt tatttaaggt agtaagcatg
    39601 tctataagaa ggggaagtta tcgagggtag aagttgttat ttataacgat attataaaga
    39661 aaatattatt atataaaata ataaatagta aagaggtatc aagttgaata taatacttaa
    39721 tacctcttca aaattaaatt ataaaagtgt tgtgggaatt gtcctataca tggtaaggag
    39781 ataataaaga atgtatcttt aaagtctcaa ctaaacagca aaatttatcc aacaaacata
    39841 caataaatgc ttctttgtat ctaggtggct taacagtaag tggccacatg tgttttaaaa
    39901 ttatgtccgt ttctttttca tttatttgaa aaaataaagt tgcatttttt aatgcttctc
    39961 tagggtgagt aaatccatgt aatccttttc tatcaccttt gtaatgccaa tcataaagaa
    40021 aaaagtcgtg tagtaaagct cctctaataa cactttgaat atcaacacgt aagtgcaatt
    40081 ttttacataa tagataacta taatatgcta ctgacaaact atgttcaaga catgaaacat
    40141 tgccatgatg aggaaatgtt ctcataagtt gaactttttc agaagaaagt atctcagaag
    40201 cacattcatt aaaatatttg atttcagctt ttgacaacat tatgaaaatc tccattctta
    40261 gtaatatata aatactatac ttcaacgata atatgaaata tttcttatcc tacaaaatat
    40321 aatacccaat aatacaagta agataccttt tatggtattt taaagtaaga gagattttat
    40381 taggctaaac aatgaaaaaa ttaaaagtaa agctatagca atatatagta tttttccaag
    40441 aggattgcca aaatttatag tccatccaat accaaacctt ttattaacca ttaatgatgg
    40501 gtcatttgga ttattataca tgatgcctgc tatccaatac ttctcatctt cttctggaga
    40561 ataagatgag ttgaatttta aatttgggga attaatatat gttgctatta aataaattat
    40621 aactaaaagc gttgtaatat tcatagcagt tgatagtttt gtttttattg ataaaagagt
    40681 agtaaaaaac tgtgttgtca ttataatcat caatattaaa aacaaataac caattttatt
    40741 taaatattta atgttttcaa ctctactttc ttcaattcta tttgtatcta tcttaatcct
    40801 tgactttatg gatccaatgg aagttatata taataaaacc attaaacaaa agtcagtacc
    40861 gattaattta aatacattaa gaaatgattt atctataaaa acatcaggag acccatttat
    40921 gttccaatga gtggcaattg agtctggcaa tttattataa ttaaatgcta taaaaatact
    40981 catccccaaa gtaaatagta tcggtattaa atagattatt ttaaattttt ttattatttt
    41041 atttttctta tttataaaat ccatatctac tattaatttt gaatctacat ctatatgacc
    41101 taatttagaa taaatttctg atttaagctt cttagctttt ttatgtgtat gaatatatag
    41161 tatactctca tataataaaa aacctataat accaataaaa tatgaaagtt ccaatttatt
    41221 aaatgtaaaa accagaataa aaactaatat aaagtctata ataaaaccta aagataatag
    41281 ttttttaaat tctttatcta attttataaa gtaattataa tttttatgct cttggtctat
    41341 agaaactcca tagatgtgtt ttttacctac aaaatagggc ataaaataaa atgtagcata
    41401 catcaaaatt agaactggaa atattgtaaa tagacattca atcttactca taatatttca
    41461 cctcatactt gtcaaataaa cttgaactta gtgacaaaaa ttcttcttta ctaatacctg
    41521 ataaataaga ttttgccacc aataattcca agtcaagttt atttttttga cgagttgtat
    41581 tatctatttt cattggtagt tgagctacaa tagcaccttt tcttctatca atatttaaga
    41641 atccctcttc ttttaactca ttgtaggatt tgttcactgt atgtaaattt acaccaatat
    41701 tttctgccat acttcttaca gatggaagtg attcatttat tttcaattct cctgaagcta
    41761 tagccttagt tatttcttct ttaatttgta cataaataga tttatcacta ttaaaatcta
    41821 aatttaaaac cataaaaaac ctccattatg ctttataaat gaaaacgatt gttatataca
    41881 tagtataaca taaaaaataa taacaaacac aaaatataag tttatatttt gtaaaaattg
    41941 taatttaaaa aataacataa tttttattaa aataatacag atactattta tagatagaaa
    42001 taaaaattag aaaggagaaa aaatatgtta acatatttaa tgaaaagaca aatgcataaa
    42061 aaagatgatg gaatgagtaa accaatgatg attacaggag ctgtaattac aggtgtagga
    42121 gcatatgctg tatacaaaat ggtaaaaagc cataaatcta attctcaaat ggtcaataca
    42181 aattattatg gaaatagcga ttatgatgat tataaatatg acgaatttga ttatgactgt
    42241 gattgtagag acacaaaaca agattatgaa tatgaagaat taaaaaaaaa agtaaaagaa
    42301 tttaattcaa gaagaataaa ttgtgaaaat tgtccacatg tttctcaaga agaaatgatg
    42361 caatatgtaa atagtgttaa agatgtaaag gaagatattg atttacatga agatgctaaa
    42421 aaagataata tttacaaaga agatgaatac aaaaaatatg aagaagaata agtaatattt
    42481 tgtataactg aacaaatagt aatgtcaaat tatttaatat ctagttttaa tatgtaagtt
    42541 gtaacttaac ttgaaagaat cagtatcatt ctttagatag ttaagttaca acttacattt
    42601 tgtttttata aattttaata gttctttgtg actattttgt aattttagaa atattttagt
    42661 atccagggta attgtgtata ataaaacttg tatagataga tagtatgaaa ttaagcagat
    42721 agtttaaaat taaaatgaaa agaaaggaaa tagttatgtt aaagttgttg atagttgaag
    42781 atgatagtac tatatctttt ggaataaagt atgctttaga acaagaagga tttagtatag
    42841 atatatcaaa ggatttatct agtggaaaag aaatgatttc ttctaatgaa tatagcatga
    42901 tactgttgga tgttacattg ccagatggaa ctggttatga gctttgtaaa tatataagag
    42961 gattctctca ggttcctata atattcttga ctgcttgtga tgaagaagta aatattgtaa
    43021 tgggtctcga tataggtgga gatgattata taacaaaacc ttttagaatt agagaattaa
    43081 tatccagaat aaaagctgtt ttaagaagaa aaggtaatac ttcagaagaa aataagaaaa
    43141 tacttaaatt tggagattta agtatatata cattagaagc tagagtatat aaaaatgata
    43201 aagaaatatt tctgacatca gttgaatata aacttctttt aattcttata cagaataaaa
    43261 atactgtttt aagtagaact caaatattgg aaaaactttg ggatgtaact tatgattttg
    43321 taaacgacaa tactctaact gtttatataa aaaggcttag agaaaaaata ggtgatgatt
    43381 tatgtgaacc aatctacata gaaactgtaa gggggattgg ttataaatgg ataggaagtg
    43441 aaaatagtgt ttctatataa tccagaagtg aagaagtttt taagtaagta tgttactttg
    43501 atgtttattg ttatcataat atctattgga tttagcataa tcaacgtgtc tttaactaaa
    43561 gagatggttg taagaaataa tcaagctata atagggactt tatcgagtaa gtatccaaac
    43621 ttagaaagtc agatagtaga cataataact caagggaagt ctatgaagaa catagattat
    43681 ggtcagaaaa tattaagtaa gtataattat gataaatcta ttaagataaa ctctgagcct
    43741 attatttcta aattagtttt agagactatc aaaataaata taatattagt atgtataata
    43801 tttattttga tatttgtgtt ggttgttaga tattttacgt caatttacaa tgatttatca
    43861 gatatgacta agtatgttta ctatagttca gagggtaagc catttgatat gaaaaacaag
    43921 aatcaagaag ggcagatagg tcttctaaaa actgaactct taaagatgac gacaattctt
    43981 aatgaaaagg ttgaactttt aaaaagagaa aagatatttt taaacaatac aatttccgat
    44041 atatcacatc aattaaaaac tcctatgact tctttaataa tgttgaatga tttattatat
    44101 aatgatgtac catacgaagt aaaaatcgat tttttaaata agataaaaaa tcaattaaat
    44161 agaatggatt ggttgattaa aagcatgctt aaattatcaa aggtagaagc aaaagtgata
    44221 aattttaaaa aagataaggt aaaatttagt gaactcatac atagagcaat gctatctatg
    44281 aaaataccta tggagattaa aaatcaaaaa ctgactatag agggaaatga taatgtatct
    44341 tatattggtg atattgattg gtctgtggaa gcactagtga atataatcaa aaattgtgta
    44401 gaacatactc ctgaatttgg aaatataatt ataacctata aagaaaatcc attattttct
    44461 gaactaataa taaaagatga gggtgaaggt atagataaaa aagatatacc acatgtattt
    44521 aaacgattct atagaggaag aagtagttca aaagaagata gtgtaggaat aggtcttgca
    44581 atgtcaaaat ctataataga aagccaaaat ggcgatatat atgtaaacag cgaaaaaggt
    44641 aagggtacag aatttcatat aatatttcat aaaatgtatg atagtgacta atctgtaata
    44701 tttaattcac tttatagtaa tagccaaaac ctaatatatg aagtatagaa tataaatatt
    44761 ggaggtagtt atggaaattt taagagtaga aaatctaact aaaagttatg gtaaaaatga
    44821 aacaaaagtt gatgctataa aaaatgtaag tttatcagtt gaaaaaggaa cgtttatagc
    44881 aataacaggt ccaagtggaa gtggtaaaag taccttatta catttattag gaggagttga
    44941 cagaccaact agtggtaagg tttatataaa tgatgttgat atatataatt taaaaactaa
    45001 ggatttggcg atatttagaa gaagaaatat aggtcttata tatcaatttt acaacttaat
    45061 tccagtctta aatgtgaagg aaaacatatt gcttccagca gagcttgaca atagagatat
    45121 tgatagagaa tattttgatg atttaatgaa aacattaggt ctaattgata gagaaaagca
    45181 ccttccaaac caattatcag gaggtcaaca acagagaacc tctataggac gtgcattaat
    45241 taatagacct tctataatat tagcagatga gccaacaggt aatttagata gtaaaaattc
    45301 aaaggaaata ttagaattgt taaaattgtc agtaaaaaaa tacaatcaga cactaataat
    45361 gataactcat gacaaaaata tggcacttca agctgataga attataagca tagaagatgg
    45421 aatcataaaa agtgatgagg tgatgtagat gaatttatat acatcactaa ccattagata
    45481 cttaaaacaa aataaaagaa gaaccattgt aaccataatc ggtataatac tttcaacagc
    45541 tttaatttgt ggtataggaa atatatttga aagttttatg gattatcaaa tgagagaaac
    45601 tataaagaat gatggaagtt tccatgttac attttatgat gtaaatagaa aaaatgtgga
    45661 atatgtaacg aaatcagctg aaatagaaaa acatgcattt accaaacaac ttggatattc
    45721 taaattagaa aatagtgaaa atgctatatt aagtataaag caatatgatc aaaatgcaat
    45781 aaacggatat aaagtttcta taaaagaagg tagatttcca gctaaggaag gagaaattgt
    45841 tttaagtgaa agtattatta atcttataga tgataagtta aaaataggag ataagataac
    45901 tttaaaagta ggggatatgt ttgactcaag caagaaaaag attgatagta tgacatttca
    45961 tgaaggtgat tatatagcaa atgaaaaaga tagaactttt aaagttgttg gtataattaa
    46021 aaaacctggg tttgaacgtt ataatggaat tgcaacagct atagcctact ttaatcctat
    46081 gaataattac aatgatacaa ttaatgtatc agtagcagta agaaatccta aagatgtgta
    46141 taagataagt aataaaataa gtaaaaatat atattcaaat aaagataaag aagcagtttc
    46201 tgatatgata aaatacaatg aacatttatt gaggttacaa ggtgctagta agtattcaaa
    46261 tataaatagc tctataaagt ctataattat agcagtaact attttagtaa tcatatgtac
    46321 aattgctaca gtgtacaatt cctttagtat ttctataaat gaacgaaaaa aacagtttgg
    46381 gatattaaat tctataggtg ctacatctag tcaaattaaa agattagttt ttatagaagg
    46441 tattataatt agtttaattg gtataccaat aggactaata tctggaacag tagctataga
    46501 cctattgttt aaaattataa ataagtattt tactgaatcg gttgttacta agatgagttt
    46561 gcagatagtg tataatccaa taataattat tgttagtata ataatagttt tgcttacaat
    46621 ctttatatca attctactac ctgcaatatc ggcttctaat atttctcccc ttaatgtgat
    46681 taaaaatact ggagagtata aagtgggcaa aatcaaaagc tcaagactta ttaaaatgat
    46741 ttttaaaact gaaggagtac ttgcatataa aaatattagg agaaatagaa aaaaatttat
    46801 aataactctt ttttctttaa tggtaagtat aataatattt atatctttta gtggctttac
    46861 attactttta ctaagaggtg aagaaattag aaattctcaa agaaaatatg atttgtattt
    46921 aactgcaaag aacacagcta ggtctgtaga ggatactata agtgaactag aagatattga
    46981 tgggataaaa aactttgaat tggcaacagg acaatatgtg tctataagag taagtgaaaa
    47041 taaaataaat aaatccaagg aagatttaat caggaaatat tatcaaaaat ataagattgg
    47101 agaaagttat gaatatgatt tcagtaataa tgaattgatt tttccgggag attttgcagt
    47161 aaaaaacaaa ataaataact tagtacaggg ctcttttaat aaagagagag caattgaaga
    47221 aaatggtgtt atattagtta gaaaaagtgc aattgaagaa aatgggaaga aaggtgtagt
    47281 agaacttacc aactataaag taggagatac agtaaattgt gaatatcttg atgaaaatgc
    47341 cttaagtaaa aaagtaaagg tcaagattct tgctataact gatgaagaac gtctaggttt
    47401 tggttatcaa aatatggggt tacaatttat aacttatgat gaagttgcta aaaatttaaa
    47461 tttaaaatta agtaaaagcc ttatatttat tgattcagga ggaagcatta agactaagaa
    47521 ggaaatagaa gctttggcaa ataaaaatga ttttaacttt tatgatgaaa tttcaagcag
    47581 tgaaagtgaa aaacaagatt taaaggttat taaaatattt gtatatggtt ttatagtagt
    47641 gatatcttta gtgagtgtta caaatattct aaatacagta agtacaagta taaatctaag
    47701 aaaaagagaa cttgcagtaa tacaatctat aggggttact cctaaaggat ttaggaaaat
    47761 gatatattta gaaagtttta tatatggtat actgtcattg ttgtttggaa taccaattag
    47821 tattggtata attctaatta tgaataaact tatttcaggt gtaattgaat tttctccgat
    47881 tataccgtgg acagccatag ttatctgtat agtaagtgtt tttataataa cttttatagc
    47941 agggtatata ccaatgagta aattaaataa agaaaatata atagataata taagaagaga
    48001 aagtatatag atataaaaat aattcttaac tatataaaat attattaaaa tcatttaagt
    48061 ggtataaaat attattatat cacttaaatg attttttatt tatataagaa atctaataat
    48121 aaattactag aggtatttaa ctatttagaa agaattggta ttatataaag taagagaata
    48181 tataataaga aagaatattt gattttattt gaaaacaaaa gaaaaagaag gtgattacta
    48241 tttctcatat aactgcgaag aatatgtata aaagtttaga ggaaagaata aacaagtttc
    48301 cacaaggtgc tccaccatct gatacattat acaaaatact aaatgtacta tatacagaac
    48361 aagaggcgaa gttagttgct cagcttccaa taaagccttt cagagtaaaa acagcagcta
    48421 aaatttggag tgtaagtgaa agtgaagcat atagagtatt ggataaactt gctagtaagg
    48481 ctctgatact agatatagaa gataataaag ggaagaaata tataatgcct cctccaatgg
    48541 ctggtttttt tgagtttgcc atgatgagaa cgagacacga tatagaccaa aaacttttgg
    48601 cagaacttta ctatcaatat atgaatgtag aagaagattt tatcaaagat ttattttatt
    48661 caacagaaac gaagcttgga agagtatacg ttcaagagga agttttaact aatgataatg
    48721 aggttagtat tttagattat gaaagggcta ctcatataat tgatgaatca actcatatag
    48781 gtataagtat gtgttactgt agacatagaa tgcaacatgt tggaaaagct tgtgatgctc
    48841 ccatggatat atgtatgacg tttgacaatg tagcaaattc tttaataaat aataaatttg
    48901 caagacgtgt ggataaaata gaatgtaaag aactacttca tcaagcatat gaacataact
    48961 tagttcaatg tggagaaaat gttaggaaag gggttacgtt tatatgtaat tgctgtggat
    49021 gttgctgtga agcaatggta gcagctaaaa gatttggaaa tcttcatcca gtacagacaa
    49081 caagttttat accaaatata aaccatgaaa attgtgtaaa gtgtggtaaa tgtataactg
    49141 catgtccaat agatgcgata agcaaggtta aggaagatgg taaagaatat ataaaaattg
    49201 atgaggatag atgtttaggt tgtggagttt gtgttagaaa ttgccataaa aatagcatta
    49261 tgttattaaa gagagatgaa aaaataataa ctccagcaaa ttcagtacat agagcagttc
    49321 tcatggcaat tgaaaaaggg cagttacaaa atttaatttt tgataataat gctctggcta
    49381 gtcatagagc tatgggagct atactgtcag ctatattaaa gcttgaacca gctaaaaaga
    49441 ttttagccag taaacaatta aagtcagtat atttagataa attgttaagt atgaatgata
    49501 aatagaaact aacttaaaaa aggcaaagtt ttagacttat ctatatctta ataaacttat
    49561 catttaatat ttaaatttaa tttttacaca tataaaactt ataacttaaa taaaaaaagg
    49621 ctatattcaa ttaatattac ttgaatacag ccttttttag ttatgttaag ctatttcttt
    49681 tatttgctta aatgagtttt catttccatt tccaccaatt tgtgttacag atttaaatct
    49741 catagtttta aatagttctt tttgattata atctagtgag tttcctacta gcattacagg
    49801 agatttagtt tttccagcca aaactccaac agataatccg tctattaaat catcttgttt
    49861 attcattcca tttttagcaa catataaatt gtctatctta gaatccttgt aaaattcttt
    49921 tattactttt gcattagttt catttctagt gttacctgat attctctgtg gattttgaag
    49981 tttactttct atatttttag aaactgtata ttctccaccg attacataag atttatcaat
    50041 ctttttgttt ttaaataagt tatttatttc agttatatta ctattttcat tagtaagtat
    50101 tataggcata tcattttgag ctgatacagc tccaatgctt actgcatcgg ctaatccttt
    50161 ttcgccatta actactgaaa tctttgatat attgctaata ttgttcaatt ctttagcaat
    50221 gttcatagaa gtttgatatc tatcacttcc tgaaattcta gatacagaga tattgtttga
    50281 ttttatagta tctaaagatt tttcatttat agaagcctct ccaccaacta catatacatt
    50341 tttaactttt aatctcttta attcagccaa agttttttca tttatttgag agcttccagt
    50401 caataatata ggagcgtttt tcttgtatgc aaatggtgtt gcggccaaag catctgcaat
    50461 tgctgaatcg tttattaaaa ctgcattttc agcattttcc caacctgctt gacttatctt
    50521 aatagaagtt tcatatctat cagttcctgt aagtgcactt gcatttactt catcttgata
    50581 tgtaacctca aatctagcat ttggacttcc taagaaaaca attacgcctc cttttggcaa
    50641 tctaactcta ttgttctttg taactaaaga atagtttaca ggaacacctt tatcatcata
    50701 aacagcaaaa gctgaatttt gaggaagatt aacttctatt tttttatttg cgatatcgtc
    50761 accaatctta taccattttg cataaccatt ggattctagt tcacaagtaa aagatttttc
    50821 tgctggcaaa ttagttatag aatcttcact aacatacgtt agtgttccaa aagataaata
    50881 ctctgtacca ttttctttat gaagtttaat gtcggataaa tcacgaccta ttacaccagg
    50941 tatttctata aaagcatttg agttattctc atccattatt ttagtgttaa ctatataacc
    51001 tggagtttca tcagaaagac taaaacttgc ttttacagag ccaaacatat agctttgaga
    51061 agtatatttt tcatccacta gatagtaacc tttgccactt ctttttttcc acacttcttt
    51121 gacactattt gatatattgt tgtcatctac tttttgagct acatagtata aacttgctgt
    51181 ctgacctaat ccagggacat catcataaga gctcatattt aaatatgtga tattattttt
    51241 ttcttttaca aattttaaac aactgttacc cttttcagat acaaatctat cttgacctat
    51301 gtatacgtat ttatcttcag gtccattttc tatataagga gaagatactg ttaaagtacc
    51361 attatcatta acatctactt ttatcatatt tgaagaagca taaagaccac tattttcttt
    51421 tagagagcta ggcattttaa cttgttgtgg cttactaaat gttttatcag gttttatttc
    51481 tttaatttta cctttttctt ttaatgcaga tagtaagatt tcttgtccaa ttatttcgtt
    51541 aagttgacta cttccaccag aagaaagaac tgcaactgcc atattttcat ctggaagaac
    51601 tataagatta ctgtggaata ataaagagtc tccacctttt gtaagagctt ttaaattata
    51661 ctgattaaat ggataagtgt tgacacaatc ccaccctaaa ccatatccaa gtatagaatc
    51721 ttctccttca ggccatagac catttaaata ttctttgttt tccatagctt ttactgaagc
    51781 aggagaaaga ataccatttg aatttttcat aaatgtttgt gcaaatgtac atagattttc
    51841 tgcacttgaa tataaaccac ctgcacctat agcattaagg ttatcttgtg gaactgcatc
    51901 ttcccaataa ggtacatatg cttttgctag ttttgaacta tcaaaactat tttctgtagt
    51961 ttttgtattt tgtaagttaa gtggattatt tatgtattta tcaagaaaat tagtaaatga
    52021 cataccagat actctttcta ctaaaatttc agctaaagta aatccatcat tacaataaac
    52081 ggaaaaagct cctggtttag cttttaatct ttgtttttgt aattctttta agaaattatc
    52141 atgaccataa gaatcattgt ctgctaataa aatagtgttt ttaaaactac ttcccatcaa
    52201 ccctgatgaa tgatttaata acattcttgg agtgatttcc ttgtatctat catcagccat
    52261 tttaaattca ggtatatact ttacaacagg agtatctaaa tttaattttc catcatcaac
    52321 caacttcata acagctgttg tagtaaacat tttactgata gatgcgatac tatacatatt
    52381 atccttattt aagtttttgt tatcctgttt gctgtaaact ccaccattac cagaaatctc
    52441 aattttgcca ttatcaatca aagcatattg agcacttaca gcaccatact ttgatagcaa
    52501 agtttggatt ttctctttag caagagcttt agtttttgtg taagattccg cgtttttact
    52561 ataatcatgt aattctatat cagaactttg atatttttcg gaattatctt ttgtattatc
    52621 agcaaaagta atatttggag cagcagtaaa taacatactc aatactaatg tactagataa
    52681 taatttagag atcctttgct taaacatatt acattacctc tttccctttt taataattta
    52741 taattagcat aacattctta attattttaa tcaacagatt attatcaata aaaaaagctt
    52801 ttataagtat agctttttat ataacagaga aaaatataaa aataatattt gttgttgtat
    52861 aaagaataaa gggtataggt aatatataaa taaaatggag gaattttaga catatgtata
    52921 agaatataaa taagaagcaa cttaaagaaa tgatgaaaaa tgaaaaggat gttttattat
    52981 tagatgtaag aactaaagat gaatttaagg aatataaaat agaaaatgct ataaatatat
    53041 ctttacaaga tttaatcaat aatatagatg aaatttacga ttataaagat aagaaagtag
    53101 tagtttattg cagaagtggt catagaagtg ttactgcatg taatttgtta gctgaagaag
    53161 gttttgagca tttatataat ttaaattcag gaataattga ttatatgagt taaataaggt
    53221 aagttataca ttaaatacta tgtatagctc tgtttattaa gtaggaatat atctaaatat
    53281 ttataagata aatttaggaa agaacgaatt ttttcgcttt tttctatgac agtttttgta
    53341 gtaaatatta gtttttaagt tggaaaaagg tagtagcttt ttagctacta ccttttaata
    53401 tgaacttaga atattattaa aaaaatatat ttaaagacag aattaatttt ttaatgacca
    53461 gttaaattac tatcgccaaa tttatcatta aatggtttta taactctatt tataggtcct
    53521 tttagaagta cgtttaaaca aatagacaga atcataaata gtaatagaac tagtatatct
    53581 ttagttagat ttggagcata tataccacca actgcttccc ttgtagcacc tattgcatag
    53641 gtaaatggca ttatagggtt tattctttgg aagaatgtag gtgtaacttg tatagggaat
    53701 gtaccaccag aagaaccaat ctgaacgact aatagtacta ttgcaattgc ttttcctaca
    53761 tttccaaata cagaaactaa agaatacact ataaagttaa ataccatact agtaaacata
    53821 agcagaacta tcaataaaat tggatgtttt gctgttactc ctaacaataa tatatctcca
    53881 gttcctatta taaaaccttg gacaagagct atacttaaaa aagtaagacc tcttccaaag
    53941 taaatttcat aaggtttata gtttccatgt acagatgtag acaatagtgc tgaaataagt
    54001 aatataccaa cccatgtaga aagaacacta taaaatggtg tcattgcaga accataattt
    54061 tcaattggat ataatttctc tgttttcacc tcaacaggtt cttttaagaa attagacttt
    54121 gtcaatatat cactttcaag caagctgact aattttttca tatcttcacc attactaatt
    54181 ttgcttaaag tatcaatcaa atcatccaac attccttttg ctaaaggaag tctttctctt
    54241 atcaatgata tactttcctg tgcatttcct gaaagtttta gagaagtagt aagtatttct
    54301 tcaacctttg gaagttttgc ttctgcctta tctaaaacag taattatatc atttgctact
    54361 tttatactgt ttgcaaatat actatttata ggttttgata tttttgagtc aaaattattt
    54421 aaaatattta aattaattct tccaatacca tttgatagac ttaaaacatt attcaaagca
    54481 cttatagatg gttgttgtcc agatataact ttgtttttaa tatcatttaa tgttgatata
    54541 gatgaatcta ttttattgct agagtcttca agattatcta ttacatcatc caatctatta
    54601 tttgatgtaa gttggtttaa tttagttaaa aagtccacca aagtatcgtt taaagattgc
    54661 aaattagaaa gtttttctga taaattatct atcaacttag gtacatcttc actgccacta
    54721 tttactgcat caattaaatt taatgtaaga gaagaagcag aagatgaaag gtcaaccatt
    54781 aaatttaagt cagacttaat aagaggagaa agttcgtcta aattatcatt tgtatcctct
    54841 aagaattttt ttaagtcact tgataatagt tttgtatcat tcagagtctt tttaattgta
    54901 ggtaaatcag atttaatatc tttaactgta tcagataatt ttgaagtagc atcagaagct
    54961 aaatccacag tcttatttat atggtcaaat ctcttttgaa ggtcaataag ggaattttca
    55021 acttttgtca attttggaag actgtgttca attcctgcac caactccgtt tgatatacca
    55081 agaacgattt cactaactgt ttttactata gtctgattaa cctgtagttg tattgtagaa
    55141 gcacctttat ctgtaatctt tggtgcaact gcatttattt tttcattaac agtatagata
    55201 atttcgcctt ttttaacatc atctgtaatt aaagatgtca aatcttttgt aaaatttttt
    55261 ggaatcttaa gtgatgcata ataagtacct tttttaacac cttcaagagc agttttttca
    55321 tctacaaact gccaacctaa actcttgtta tctttgagtt gttcaattaa ttggtctcct
    55381 acattaatct tttgtcctgc tatttcattt cctttatctt catttgttac tgctacaagc
    55441 atattagcag tgcttccata agggtcccaa gatgccttta tattgaacca agcatacaga
    55501 gatggtaaaa aagcaagacc taaaactatt acaagtacgg cataattgcc acgtatatct
    55561 tttaggtcac ttttaaaaat ttctaatata ttttttaaac cctttgaagg tcttaaattc
    55621 ttgatattat tccagtttaa aatttctttt aaactattag tttttttcaa atgtctcacc
    55681 tcctaaaata ttttgataaa gaaaaaagtt agatttataa tcaattttaa attatattac
    55741 tttttacaca aatagtaaag ttaaaatttt gtcttaattt taa
//
LOCUS       DAMJWO010000012        55351 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.013, whole genome shotgun sequence.
ACCESSION   DAMJWO010000012 DAMJWO010000000
VERSION     DAMJWO010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 55351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55351
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.013"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            34..1314
                     /locus_tag="PC366_000815"
     CDS             34..1314
                     /locus_tag="PC366_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HDF2576355.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNIAEILANEPNEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKTLNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIESDICSA
                     TAIRTSLKENTDLFHLKNVIPEKTYNILNEKVDNGFLPMFDDFFFDILKTIILRDMDT
                     LKEYFEVNEGIENRIYKDIFTSEFLHELQLAIKSKRYTLTKIKRTLNNILLGIKKSDM
                     QLIKNIDTIPYIRILAFNDKGREILKEIKNKSEIKIINKFSNISFSLDDTIFKTLISY
                     DIKATNIYNSIYYKNNKDLVKGPMDFYTHPIYVK"
     gene            complement(1577..2968)
                     /locus_tag="PC366_000816"
     CDS             complement(1577..2968)
                     /locus_tag="PC366_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDF2576356.1"
                     /translation="MYKLIDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKYP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEIINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLIPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKIY"
     gene            complement(2979..4199)
                     /locus_tag="PC366_000817"
     CDS             complement(2979..4199)
                     /locus_tag="PC366_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HDF2576357.1"
                     /translation="MSKIVVNQDKITDLKRILEICPFGAIEEKSGIVEISAGCKMCKL
                     CVKSGPKGAFEFIESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCSNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFIDKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSAPEKIENTTGKITLCKVEKKELKSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMIYKLADKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDNNQKYMASAAK"
     gene            complement(4213..5001)
                     /locus_tag="PC366_000818"
     CDS             complement(4213..5001)
                     /locus_tag="PC366_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003457975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF2576358.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKEDKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEVKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLNTKDREIPVYSLDDFEDKDENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRGNADELSFALVNKLEELKLV"
     gene            complement(5018..6292)
                     /gene="larA"
                     /locus_tag="PC366_000819"
     CDS             complement(5018..6292)
                     /gene="larA"
                     /locus_tag="PC366_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HDF2576359.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRNVNPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHISTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSVLPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSKVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMISACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTIPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEMANSIVGKESKVVVIPDGVSVIVK"
     gene            complement(6410..7123)
                     /locus_tag="PC366_000820"
     CDS             complement(6410..7123)
                     /locus_tag="PC366_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDF2576360.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLEDILEL
                     RIILEIEIAKLASKRITSSEVIELKHIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     EKAKEHMDFISKNYRKNEN"
     gene            7248..8507
                     /locus_tag="PC366_000821"
     CDS             7248..8507
                     /locus_tag="PC366_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HDF2576361.1"
                     /translation="MKKNKIIAFFAPAIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNGQISKHEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNENLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSSPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGVLAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTILQIVVIIYLISAVFIAKK
                     HMKTLSTNGKLMRYKNTFFIKKFSRKK"
     gene            8775..9341
                     /locus_tag="PC366_000822"
     CDS             8775..9341
                     /locus_tag="PC366_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2576362.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKHLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(9542..10747)
                     /locus_tag="PC366_000823"
     CDS             complement(9542..10747)
                     /locus_tag="PC366_000823"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HDF2576363.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNTSKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNNVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDNNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRSSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILECLDKYVDSYDIIDDEELAIFVSAKSEHEIDRVLEIVKRNNYSE
                     SAKKLLKID"
     regulatory      complement(10850..10956)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(11048..11416)
                     /locus_tag="PC366_000824"
     CDS             complement(11048..11416)
                     /locus_tag="PC366_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HDF2576364.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDTKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     gene            complement(11468..12745)
                     /gene="obgE"
                     /locus_tag="PC366_000825"
     CDS             complement(11468..12745)
                     /gene="obgE"
                     /locus_tag="PC366_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HDF2576365.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            complement(12856..13146)
                     /gene="rpmA"
                     /locus_tag="PC366_000826"
     CDS             complement(12856..13146)
                     /gene="rpmA"
                     /locus_tag="PC366_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HDF2576366.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            complement(13160..13477)
                     /locus_tag="PC366_000827"
     CDS             complement(13160..13477)
                     /locus_tag="PC366_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HDF2576367.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECIVKDTHVKDAQLLLNHFQLAVKEIKREYPKNIKI
                     LKK"
     gene            complement(13492..13803)
                     /gene="rplU"
                     /locus_tag="PC366_000828"
     CDS             complement(13492..13803)
                     /gene="rplU"
                     /locus_tag="PC366_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HDF2576368.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            complement(13904..15325)
                     /locus_tag="PC366_000829"
     CDS             complement(13904..15325)
                     /locus_tag="PC366_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HDF2576369.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNIYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSTIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCTHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYKTNLEAAKEIVRQLIIRDIAGIIIIDFIDMHKKKHQ
                     KEILHILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDSIEKEIMRISEHTVYKNIMVEFNDFIFEQIKEYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            complement(15343..16044)
                     /locus_tag="PC366_000830"
     CDS             complement(15343..16044)
                     /locus_tag="PC366_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2344 domain-containing protein"
                     /protein_id="HDF2576370.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGTESQGEYVDIEIEEDDLSVEEFLNKVSIQLPDGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKTNLNTNILIPKILEMFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            complement(16046..17890)
                     /locus_tag="PC366_000831"
     CDS             complement(16046..17890)
                     /locus_tag="PC366_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HDF2576371.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFI
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            18209..19402
                     /locus_tag="PC366_000832"
     CDS             18209..19402
                     /locus_tag="PC366_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HDF2576372.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDAEVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            complement(19614..20696)
                     /locus_tag="PC366_000833"
     CDS             complement(19614..20696)
                     /locus_tag="PC366_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HDF2576373.1"
                     /translation="MKKIRKLATKLLIATMVLTSCMSVTVYGMTAKDVTAKTPKSYVA
                     GTNSIYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKIRVAYNHIKNNTTYVNWNA
                     AEGANTAYTLVTKKGACSGMCRSLKALCDAMGIECYYVHSTTNDHQWNLIRFEDGRLY
                     HVDIDANKSAGADIIYKSLTHPLPFDKKAYPAVGESVKTQNPTPTVKKPTPAKPSAPV
                     GPGNHTMIADQEEAILDEVYGNNLRPKIERYEGVPCSLINSSINTIKFTSKNSNLDPS
                     RHTVSVIGFMNTPYGMVALAPDGVPVEYPFEYDKPFSLDFTGKNLSAAELSKKCKNNN
                     VIIKIEIGEIEPNSGRGQVRYARYVN"
     gene            complement(21260..22051)
                     /locus_tag="PC366_000834"
     CDS             complement(21260..22051)
                     /locus_tag="PC366_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576374.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLDRHKSIVMGFKKVLGYISIIAFLIS
                     GFMWYYNNSLQHNMYNLGKELDGEIKQLAERHDMTNIGEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYEREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFAFGLLCIIAYFILRFKISLIKNNN"
     gene            complement(22055..22384)
                     /locus_tag="PC366_000835"
     CDS             complement(22055..22384)
                     /locus_tag="PC366_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2576375.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
     gene            complement(22869..23282)
                     /locus_tag="PC366_000836"
     CDS             complement(22869..23282)
                     /locus_tag="PC366_000836"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HDF2576376.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRI"
     gene            complement(23323..24453)
                     /gene="rodA"
                     /locus_tag="PC366_000837"
     CDS             complement(23323..24453)
                     /gene="rodA"
                     /locus_tag="PC366_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HDF2576377.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGT
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            complement(24538..24822)
                     /gene="minE"
                     /locus_tag="PC366_000838"
     CDS             complement(24538..24822)
                     /gene="minE"
                     /locus_tag="PC366_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HDF2576378.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            complement(24840..25637)
                     /gene="minD"
                     /locus_tag="PC366_000839"
     CDS             complement(24840..25637)
                     /gene="minD"
                     /locus_tag="PC366_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HDF2576379.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            complement(25661..26344)
                     /locus_tag="PC366_000840"
     CDS             complement(25661..26344)
                     /locus_tag="PC366_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HDF2576380.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKIEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYENESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            complement(26442..29420)
                     /locus_tag="PC366_000841"
     CDS             complement(26442..29420)
                     /locus_tag="PC366_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDF2576381.1"
                     /translation="MEENKQVDRLKIIKIVMSVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMLTSMAALENGLD
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKMNVKEDRIEEV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVARQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            complement(29432..29920)
                     /gene="mreD"
                     /locus_tag="PC366_000842"
     CDS             complement(29432..29920)
                     /gene="mreD"
                     /locus_tag="PC366_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HDF2576382.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAAIIGLIKDITVGGIFGVNALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFVKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            complement(29935..30828)
                     /gene="mreC"
                     /locus_tag="PC366_000843"
     CDS             complement(29935..30828)
                     /gene="mreC"
                     /locus_tag="PC366_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HDF2576383.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDVANFKDNSKKVKKLEEENEKLKKDMIA
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISASVVGKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            complement(30838..31848)
                     /locus_tag="PC366_000844"
     CDS             complement(30838..31848)
                     /locus_tag="PC366_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HDF2576384.1"
                     /translation="MTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAVG
                     EEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVP
                     FGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVEEPEGNMVVDIGGGTSEI
                     AVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEE
                     INMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMEN
                     GIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTGKSVEDQEIFEKVLMMNT
                     KN"
     gene            complement(31969..32628)
                     /gene="radC"
                     /locus_tag="PC366_000845"
     CDS             complement(31969..32628)
                     /gene="radC"
                     /locus_tag="PC366_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HDF2576385.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGNKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIRNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            complement(32673..33257)
                     /gene="maf"
                     /locus_tag="PC366_000846"
     CDS             complement(32673..33257)
                     /gene="maf"
                     /locus_tag="PC366_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HDF2576386.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV"
     gene            complement(33477..34448)
                     /locus_tag="PC366_000847"
     CDS             complement(33477..34448)
                     /locus_tag="PC366_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HDF2576387.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     IAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            complement(34464..35039)
                     /gene="rsxA"
                     /locus_tag="PC366_000848"
     CDS             complement(34464..35039)
                     /gene="rsxA"
                     /locus_tag="PC366_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HDF2576388.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            complement(35054..35647)
                     /locus_tag="PC366_000849"
     CDS             complement(35054..35647)
                     /locus_tag="PC366_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HDF2576389.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            complement(35660..36229)
                     /locus_tag="PC366_000850"
     CDS             complement(35660..36229)
                     /locus_tag="PC366_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HDF2576390.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQENNEL
                     RKAVLPEAKEFKEMDKSTYKDLGDGLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            complement(36229..37206)
                     /locus_tag="PC366_000851"
     CDS             complement(36229..37206)
                     /locus_tag="PC366_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HDF2576391.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFTKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADLSSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            complement(37229..38566)
                     /gene="rsxC"
                     /locus_tag="PC366_000852"
     CDS             complement(37229..38566)
                     /gene="rsxC"
                     /locus_tag="PC366_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HDF2576392.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKPIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTITGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDIQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            complement(38782..39726)
                     /locus_tag="PC366_000853"
     CDS             complement(38782..39726)
                     /locus_tag="PC366_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576393.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKKGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIESISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            complement(39837..41111)
                     /locus_tag="PC366_000854"
     CDS             complement(39837..41111)
                     /locus_tag="PC366_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF2576394.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSNQNNPTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGDVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGTNNSSNSNSTNNSDKKPSSEESIEGKNGKVTSAVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKSKNNGWYKVKLSSGTIGWVSASYISETNEGTKEKPNSSSN
                     QNSQSNSNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            complement(41243..41614)
                     /locus_tag="PC366_000855"
     CDS             complement(41243..41614)
                     /locus_tag="PC366_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2576395.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            complement(41842..42441)
                     /locus_tag="PC366_000856"
     CDS             complement(41842..42441)
                     /locus_tag="PC366_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576396.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            complement(42642..42854)
                     /locus_tag="PC366_000857"
     CDS             complement(42642..42854)
                     /locus_tag="PC366_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HDF2576397.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDDISIEKLKEVIAELGFELKGIE"
     gene            complement(42927..44642)
                     /locus_tag="PC366_000858"
     CDS             complement(42927..44642)
                     /locus_tag="PC366_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2576398.1"
                     /translation="MKRIKVLTVVLAITLMVAGCSNTKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKNVTSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQNHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEEARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKAIECLAKVEYANINSVNQNDNKVKNQKKSAKKNSKKLTPEEEAKAKKAEE
                     DRIKKEAEKKKNREKEEVKKSLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKNYDLALVGWKLSIIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSNSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            complement(44642..45196)
                     /locus_tag="PC366_000859"
     CDS             complement(44642..45196)
                     /locus_tag="PC366_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HDF2576399.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEHYNKIYGKKGKN"
     gene            complement(45189..45791)
                     /locus_tag="PC366_000860"
     CDS             complement(45189..45791)
                     /locus_tag="PC366_000860"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HDF2576400.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNISIVDADIISRKIFEDKLL
                     LEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKELNSLTHPRIREKIISEIEELR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSKQEALSRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            complement(45800..48448)
                     /gene="polA"
                     /locus_tag="PC366_000861"
     CDS             complement(45800..48448)
                     /gene="polA"
                     /locus_tag="PC366_000861"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HDF2576401.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKEYKAGRKGMPDELAEQLQPLKDLLDKFKINR
                     LEIDGYEADDIIGTVSKKAENNGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPAQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLDSMVFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSDDTEHVEEKIEILKLKDTEKFIDEVNKKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITIAEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETIPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNMDVHLDVDLNVGSSWYETK"
     gene            48767..48849
                     /locus_tag="PC366_000862"
     tRNA            48767..48849
                     /locus_tag="PC366_000862"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48801..48803,aa:Leu,seq:caa)
     gene            50224..51633
                     /locus_tag="PC366_000863"
     CDS             50224..51633
                     /locus_tag="PC366_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HDF2576402.1"
                     /translation="MIFSSLIFLFLFFPVTLICYYLANPKYKNVMLLLASIAFYAWGE
                     PKYIFLMILSIIVNYIFGIKVSGSKNKKMWVVLSVIYNISILAVFKYSNFFIDNINFL
                     FNTDITIPEVKLPLGISFFTFQIMSYVIDVYRNDAKVQRKLANLALYISLFPQLVAGP
                     IVRYQTVADSIEYREHNWDKFTQGVNRFVVGLGKKVILANQLGVIADGVFNKSAGDLS
                     RLEVWLGIVCYTLQIFYDFSGYSDMAIGLGKMFGFEFLENFNYPYISQTVSEFWRRWH
                     ISLGTWFKDYVYFPLGGSRVSKAKLYRNLFVVWFLTGMWHGASWTFIIWGLYYGILIS
                     VEKAFLEKFLYKMPRIVRHIYLLLIVMIGWVFFRVDDLPAAIKFIGIMFGAGNYPVIS
                     DAFNVFIIEYWYIIVGAILLSTPIVKVVKSLLIKKNKNTLNSTLYQVTNVVFIVSCMF
                     IVIIMLSSSTYNPFLYFRF"
     gene            51649..52851
                     /locus_tag="PC366_000864"
     CDS             51649..52851
                     /locus_tag="PC366_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576403.1"
                     /translation="MSKKKPRIVAISFLIIVFGFFILNFTLPKKKLSITENRNLAKFP
                     TVENLKKCDFIAKFEEYFNDHFAFRDEMISINTRTQANLNKTKVGNYYLGKDNWILGM
                     FPEILDQKQLSRYEKSINYLSNLSKDMGKNVYFTMMPHKTNMLKHLYPKYVDNMDNID
                     INLKNFKNRLNPDLIKYIDMDEYFLSNYSDKERENLYFKTDHHWTGYGAFEGFKMMAS
                     NMDLGLSKQDLDKHFSSYKKSIITDKKFIGSYNQNIDMLIKENEYVVYMTKDNQDYSF
                     DINGEEKEEKEEKEVYATERDNKEWDYGGAYIRGAKTNILTIKNPKALVDKKILIFRD
                     SYQAPTTLLFADMFKEVEIADPRNINSIYKTYKEIIEESNADIVMFMYNSSGFDSMID
                     SMIDKGIK"
     gene            53052..54035
                     /locus_tag="PC366_000865"
     CDS             53052..54035
                     /locus_tag="PC366_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576404.1"
                     /translation="MKEVFNVHIMQSQNKKIKQKYYLTKDGWLLGNFAKLLSDYHIKS
                     YSKAINNLSKLNRKKDFYFVSLPHKTNMLKHLYPSGIEGKNNIDINKENLEKQLTDIN
                     FLDIDDYFYRSFTEKEREKFFLKTDHHGNSLGAFEEYKFILDKLDLGLSKSEIDSHLK
                     RYSTRYVNDKVFIGSYNKKMGYPLKKKESISYVEISDANYKYFISNGTKNTEINENII
                     KAKLKDKREWDYGGAYMRGCDCHILKIRNSSSLTNKKALIFRDSYQAPMTWMLADTFK
                     ELEILDPRYIKNIDMTYDEIIKNSNANVVLFMYNSFGFAGMIQEMIDKGIA"
     gene            complement(54485..54928)
                     /locus_tag="PC366_000866"
     CDS             complement(54485..54928)
                     /locus_tag="PC366_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576405.1"
                     /translation="MKKNMLYLGIVYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GICMIFQYMYWSKPERAVDYEEKIKNQRIEMNDERRVMLRDKAGRITNQIMSYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKKL"
     gene            complement(55087..>55351)
                     /locus_tag="PC366_000867"
     CDS             complement(55087..>55351)
                     /locus_tag="PC366_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2576406.1"
                     /translation="ISDVSWSEFIHQLKYKANWYGRQIVKVGKFFASSQICNKCGYKN
                     EEVKDLNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
BASE COUNT        17712 a         9885 c         6284 g        21470 t
ORIGIN      
        1 atataaaata attaaagata aaaggagtat tttatgaaca tacttggatt aatagttgaa
       61 tataacccat ttcataatgg acacatatat catttatcta aatctataga aaaaacaaat
      121 gcaacacata ctgtagcaat aatgagtgga aattttctac aaagaggcga accagcttta
      181 tttgataaat atactagagc aaaaattgct gtcgaaaatg gtgtagactt agttatagaa
      241 ttaccaactt tatttgcttg tcaaagtgct gaaatttttt ctcatggtgc tataacaatt
      301 ttaaattcac taaactgcat aaattctata tgttttggta gtgaagaagg aaatacagaa
      361 attctttata atatagctga aattttagca aatgaaccaa atgaatttaa gttactttta
      421 aaaaaatatt tagatgatgg cctgttattt ccaacagcta gagctaatgc actttttgat
      481 tatatacatc aagacaaaaa aaataatttt atacaaaatt attcaaagga acaattatca
      541 aaaacattaa attcatcaaa caacatactg ggtatagaat acataaaaaa cctcatccat
      601 ttaaacagta gtataaaacc atttactatc tccagggtcc aatcagaata taattccgaa
      661 gaaattgaga gtgatatttg ttctgctact gctataagga cttcacttaa agaaaataca
      721 gacctttttc atttaaaaaa tgttattcca gaaaaaactt ataacatcct aaatgaaaaa
      781 gtagataatg gttttttacc tatgtttgat gacttcttct ttgatatttt aaaaacaatt
      841 atacttagag atatggacac tttaaaagag tattttgaag taaatgaagg catagaaaac
      901 agaatctata aagatatctt tacatctgaa tttctacatg agctacaatt agcaattaaa
      961 tccaagcgat acactttaac caaaatcaaa cgaactctaa acaatatatt gttaggtatt
     1021 aaaaaaagcg acatgcaact tataaaaaac atagatacta taccttatat aagaatactt
     1081 gcttttaatg ataaaggtag agaaattcta aaagagataa aaaataaatc tgaaataaaa
     1141 ataataaaca agttttcaaa tatatcattt tcattagatg atacgatttt taaaacactc
     1201 ataagttatg atataaaagc tacaaatata tataattcaa tatattataa aaacaataaa
     1261 gatttagtaa aaggccctat ggatttttat actcatccaa tatatgtaaa gtagtttttt
     1321 aaaataacta tatttataaa aatcatttta ttaactcttt attatataag atacaatagt
     1381 cttactttat ttatgtacac atgcttttag gatgacaaca tcaacttaaa tattatgtta
     1441 ctttctaaat ttaagtaaat attgccatcc taaaaatttt acaatttagc ttcagattta
     1501 aaagtaaagt ttaaaatatt atatttaaat ctaatttaat attttttgtt ttgtaaatat
     1561 tattaaatta atatttctaa tatattttcc ctggatttaa aatattttta gggtcaaaag
     1621 ctaactttat atttttaatt aacatcatat aagcatctga atttgattca tgtaagtact
     1681 cttttttagc atatcctatg ccatgttcac cagaaacttg accactaagt tctctagatt
     1741 ttttatacat atagtcaaaa gtttctttta atcttatttt ccatgtatta tcatccatac
     1801 catcttttaa aatatatatg tgtagatttc catctcctgc atgaccaaaa ctttttattc
     1861 ttatttttaa tttgtcttga agctcgtgag tgtatcttat aaactctgct atcttatctc
     1921 ttggaacaac gacatcacat tcatccattt gtgtcgtaga tgcctttata gcttctaaaa
     1981 atgcacctct ggctgaccat atagaatcgt ttctttcttg tgtatctgat ataaatacat
     2041 ctaatgcacc attttctaaa cataaattag ctactttttc atattccttt tctatatctt
     2101 cagtgctatt tccatcaaat gtaagtaaaa gataagcatc tgatgtatta tctggaaact
     2161 ttttacctaa aaattcttct gctgccaata ttacatctct ttccataaat tctatagccg
     2221 ttggtattga ttttgatttt attattttag gaacagtttc tattgccatt gataaatctg
     2281 gaaatggtat aagcaaactt atacttttct ttggtaaagg aagcaatttt aatatagctt
     2341 tagtaactat tcctaaagta ccttctgaac ctactaataa atcctttata ctatatccag
     2401 aactattttt aaccaccttt ccacctacat ttataatttc tccatttggt agtacaactt
     2461 caagtcctct tacataatcc cttgtaacgc catattttac tgctctcata ccacctgcat
     2521 tagtgtttat attacctgca attgtagcac ttttttcacc tgggtcaggt gggtaaaata
     2581 aatctctatc ttgaacatat tgacctattg tcatcaataa aacacctggt tctactgtca
     2641 atgttaaatt ttcataatca acttcaagta ttttattcat tttacataga ttaatcatta
     2701 ttccaccatt tatggcaaca gcagcaccta caagaccagt accttgacct cttggtgtga
     2761 ctggtatatt atttttatat gcgtatttca ttattttaga tacttgttca gtttcaagta
     2821 catttactaa aacttcaggg tacttctcaa tccctccaag ttcatcatgt gaaaaatctt
     2881 catttatatc acttccaact aatacatttt cttctccaca agtatctatt aaaaaatcta
     2941 tatctttttt atcgattaat ttatacattt ctatccccct atttagctgc tgatgccata
     3001 tatttttgat tattatcttt gttattttct attttttcaa tcaatttagg aataatatca
     3061 taaatatcac ctattaaagc taaatgtgct acatcaagta taggcgcttt atcatcttta
     3121 tttattgcta ctatatagtc agcaccctgc atccctgcaa caaattgaac tgctccagat
     3181 acaccacaag ttattatcaa tttaggtttt acagttctac cactaagacc tatttgtttt
     3241 ttagcatcta tccaacctgc ttctattaca ggtcttgttc ctgccacttg agcgtttagc
     3301 ttatcagcta atttatatat catctccata tcttcttgtt tttttattgc tctgcttgcc
     3361 acaactatca cttcagcttc ttccagacca acttctttat ttttttcttt tacactcagt
     3421 accttaattt tagattttag ttcttttttt tctactttac ataaagttat ctttcctgta
     3481 gtattctcta ttttttctgg tgctgaaaat attttatatc ttacagtggc aaattgtggt
     3541 ctattattag gtgtgtttat atgagccatt atatttccac caaatgctgg tcttatttgg
     3601 tctaaatcag tatttgattg aatatcaagt attgtacaat ctgctgtaag acctgttcta
     3661 aatctagcgg caagtcttgg agctaatgac ctacctaatg tagttccacc aactaatact
     3721 atcgttggtt ttattttatc tataaagttt tctattgctt ttgaatatgg ttctatccta
     3781 aaatctttaa attcatcttc atcatataca aatacttcat ccaccccata agaaatcaaa
     3841 ttactgcact tatcttttat gtcttttcct acaaatacac aatacacagg ttgttttatt
     3901 tttgatgcca tctcacgagc tttacctata agctcgtacg ttacaggatg tatatttcca
     3961 ttatgatgtt caacatatac tgcaattccc ctccattcat ctttattaat ttgtacttta
     4021 ctactctcta taaattcaaa tgcgcctttt ggtccacttt tgacacacaa cttgcacatc
     4081 ttacagccag cacttatttc tactatacct gacttttctt ctatagcccc aaaaggacat
     4141 atttctaaaa ttctctttaa gtcagttatt ttatcttgat ttacaactat ctttgacatt
     4201 tattactccc ccttacacca actttaattc ctctaattta tttacaagtg caaaacttag
     4261 ttcatctgca tttcctctta caatattttt atctgtattt ggctttggag gaaatattct
     4321 tacaacttga gtaggagaac cgttaagtcc atagttattt tcatctttat cttcaaagtc
     4381 atctaagcta tatacaggta tttctctatc tttagtatta agttttaatt taaatgaagg
     4441 tagtcttggt tgaaaaatgt ctttttctac agttattaaa catggatatt caatctcaca
     4501 tacttgtaaa tcatttggca tatctatttc aacaactata ctttcatctt taacttcaat
     4561 taattttgta acgttagtaa catgaggtat atctaaaaat tcagctactt caggtcccac
     4621 ctgtgctgta tcaccatcag tagtttgttt tccacaaatt attaggtcta cctttcccat
     4681 cttcttaata ccttgtgata tggtatagga agtagccaat acatctgctc ctccaaatct
     4741 cctatcactt attaatgctc cttcatcagc tcccatcata aaactttctt caattacctt
     4801 ctttgcctga ggaggaccca tgctaagtac ttttagattc gctttcttat cttcctttat
     4861 tctaagagct gtttctaaag catataggtc atagggattc atttttgaat ctactccatc
     4921 tctttttagt actcctgtag tttcatcaac ttctactgaa gtcgttccag gaacttgttt
     4981 aatacatgtc aaaatttcca taaagtacac tcctttttta tttaactata actgatactc
     5041 catcaggtat aactactact ttgctctcct taccaactat actattcgcc atttctaaag
     5101 cttctttaaa gttaaatgca tgtttcatat gcattttttt tatcatttca ggattacact
     5161 tatctgttac cattatcaca gtatatttag ataatattct cgctagtatc tgaaattccc
     5221 attggtctgg aatcgtatct actctatcga cacttctaat tttatctaaa agttgttttg
     5281 gagaatctgc atttgctaca ttttcataaa aagattgacc tccatgacca tcattacatg
     5341 ctgaaatcat tattattact ccaccgtctt tacaagtagc ttcagctgct gtcattcctt
     5401 taacagattg ataaatattt tggtctagtg gatatccacc atttgtagtt acaacaatat
     5461 cagattttat agaatttact tttgataact ctgttacaaa tctacatcct ttagtatgtg
     5521 ctttttcgac atcaccagca aaggaagcaa ttattttttt atctttatct attacaacat
     5581 tcaatatgaa tgctaacttt gcaactttag ctgcatatac catatcctca tgaataggat
     5641 tattattcaa tttcccagtt cttgaattat cactatctat aaagtcacta cagtgattgt
     5701 acattatagt ctttgcagat gcgattcctg gaagtacgct ttttctgcca cctgaaaaac
     5761 ctgcaaagaa atgaggttct ataaaacctt ctgctatcaa aagttctgcc tcatatgcta
     5821 gtttgtttat atataaatct ccacctgaag gcaatatccc tactttacac atagatttat
     5881 catcagtaga tatatgcata actatatctt cattatctac tatttcttct cccattttat
     5941 aaattagctc ttcccttgta cttggcctat gaaatccagt tgccactata atcttcacat
     6001 caatttctgg attaacattc ctaatccttc ttaatataat tggcatagtt attctacttg
     6061 gtacaggtct tgtatggtca cttgtaatta tgactacatt ctttttcccc ttaaccagtt
     6121 cttccagaga attagagcct ataggattat tcatagattc ttcaactatc tcttcttgag
     6181 tcttatgttc tatataatta tccgattttg actccaaaac accgagaaaa cgttcatcag
     6241 gtatttctaa aatcattcct tgttttgaat acggtacttt taactttacc atttttaatc
     6301 tcccattata ataaactata aaattggtat gtggtcatac cagtttcaca tttatatgat
     6361 agtaccatta tctaccattt gcaagaataa tttattttat aacaaacttt taattttcat
     6421 tttttctata atttttactt ataaaatcca tatgttcctt tgctttctca catgcaagtt
     6481 ctacatcatt ttctacaact gcattgtata tagcttcatg ctgtttaagc aatatatttt
     6541 cattaaaagg ttctgcgatt attttttctc ttgcatcttc tataaatcca tcaaataatt
     6601 ttgatgctgt cataaaaaga ctttgaatta aataattttt acttaatgtt gctagtttac
     6661 tgtgaaattt ttggtctaat aacaccagta ctcgattatt atctttttta ttagtttcta
     6721 ctctcatttc atctattata tgtttcaatt ctataacttc agaagaagtt attctctttg
     6781 aagcaagttt tgcaatctca atttctagga ttattctaag ctctaatata tcttcaagtg
     6841 tgccattatt aagtttaaaa atcatagata aaggttctat taaagttttt tctatatttg
     6901 tacatataaa atttccttca ccctgtctgc tttctatcac tcccatagtc tctaataccc
     6961 taatagcttc ccttatggaa gttctactca cattcatttg ttcagacaat tctctttctg
     7021 atagtaattt atcccccttt tttaactctc catttagtat tttatattgt atttgctcaa
     7081 ttacttgttc ataaactttt ttactagcta tactattaaa cattttttcc tccaatatga
     7141 taatcgttgt tgtaatatat atctattata tatcttaaac cattacattc atatattttt
     7201 attactttta atataatatc ttataactca aatttacagg tgatattatg aaaaaaaata
     7261 aaattattgc tttttttgct ccagctatta tagttggagt tctagtttta gggattatcc
     7321 tatacccaaa tgaagctata aaatctgcaa gagaaggctt ctctatatgg tctaatgttt
     7381 tagttccatc actactacca tttataattg gagcaaactt aattgttgat ttaaaaatag
     7441 tggatattat agggtttatc atcaatccca taactagatt tgtatttaat gtttcaggaa
     7501 agagcgcttt agcttttgct atatctacag tatctggtta tccagtagga gtaagtttag
     7561 cttctgaatt taggagtaat gggcaaattt ctaagcatga agcacaaaga cttgtgtctt
     7621 tttgttctac atcaggacct ttattcataa taggttcggt tggtacaggt atgttccaaa
     7681 attcaaactt aggttattta atgattctct gccattatct aggaactata ttggttggtc
     7741 ttttctttag aaattatggt aatgaaaatc ttccaaagac aaaattggat ttaaaaacaa
     7801 atataaaaaa tgtaatcaac attagaaatt caagtgggaa tggttttttt gttttatttg
     7861 gaaatgctgt atttaatgga gtaaatacat tacttacagt tggtggattt gtaattgttt
     7921 tttcagtagt atttaaaata ctatctcttt ttaatgtaat ctcattaata gcatcagtta
     7981 tatatttgcc tctttcattt ttaggtgtta gtaaagaact ctgtcaagca tttgtaagtg
     8041 gtctatttga aattactata ggatgcaata aagtatctag tataacaagt tctccagaaa
     8101 ttttaagagc atctttagct agctttttga taggatttag tggattatcc atcctagctc
     8161 aatgttgtac atttctatca aaaacggaca tagatttaaa attatacata ctaagtaaat
     8221 ttgcgcatgg agttttagct gctatcttta tatttatact ttatccaatt gcaaactctg
     8281 ctgtgttggt ttctagcttt gctgatacat acaacgttat atataataat ttaatctggt
     8341 tttattatct tagctattat gatacaattc ttcaaattgt agtaataatt tatctaatct
     8401 cagcagtatt tattgcaaaa aaacatatga aaactttatc tacaaatggg aaactaatgc
     8461 gatataaaaa tacttttttt attaagaaat tttcacgaaa aaaataaaac taataaaact
     8521 taactaaata cttccatttt tttattatat ttgtcataat tttaataacc tttttaatta
     8581 gtttaacagc atagttattt catcacaatt taataatttt attagaaata tttttcaaaa
     8641 aattctcctt aatcacatat atcacacttg tataagttta ctgggaaatt tttccattat
     8701 ataatgtttc atttatatta tataataaat accgacctaa acttaccaaa tcaaactaag
     8761 aggagtggtt gaaaatggca acaagaccta tagaaataga cgaatataaa aagataatgg
     8821 aactattaca tactggcttt acttatagtg aaaatggcgt tgaaaaaaga tttagaaaaa
     8881 atcctaaagt tgcattggca ctaatgttag aagctaattt aggtctaaga atatcagata
     8941 ttttaagatt aaagataggt aattttaaag gtaatatgtt ggaaataaat gaaaaaaaga
     9001 cgggcaaatt acagtataga ccagttaata aaaatataat tgagtccata aatgaacatg
     9061 caagaaagta taatcttaaa tcaaatgact acttagtaaa tataaagaca aaggctattc
     9121 aaaaacagtt gaggataatt tgtaaacact taaatctgta taatataagt acacatagct
     9181 ttagaaagct ctatgctact actcaatttg aaaagagtaa caataattta gagttggtta
     9241 aagaactttt aaatcacagt tctgtagcca ctacacagcg atatataaga gtaactcagc
     9301 aagctattaa tgaagctagt gaaaatttct ttattggtta attataacgt atacattttt
     9361 ctattatctt attaattcac cagatattaa aaaagagtgt ctcaaaatga actttttagt
     9421 tcatgagaca ctcttttttt ataaaatcaa atatattttt attatttcaa tactggaaaa
     9481 aaggcttgtc tctctatttt gagacaccct attaaatttt cataattctt gcataaacat
     9541 attaatctat cttcaataat tttttagctg attcactgta attatttctt tttacaattt
     9601 ccaaaactct atcaatctca tgttctgact ttgcacttac aaaaatcgcc aattcttcat
     9661 catctataat atcataacta tctacatatt tatctaaaca ttctaaaatt ccatctttat
     9721 tattataccc accaaatcta actactgcac tacactcatc ttctataagt ccacttaaat
     9781 ccaatttccc ttttgaaaaa gactttatat ttgaacttct attatctatt atatctataa
     9841 tatctgcata aacagcactt cctgttgcac ctcttccagc tcccttacct acaaaagaaa
     9901 gttcacctac tgaatcacct actaaaataa ctacgttgaa ctcattatct atctttgaaa
     9961 gcatattatt attgtccact aatgctggtc taacaaatcc acttacttct cctgattcat
    10021 acttacttct agcaaccaat tttatcttac aatttaattt ttttgcatat tctatatctt
    10081 tttcatctat tgaagttatt ccttctaata ataaatcttt ccaatatact atttttccat
    10141 aagataaagt agacaatata gataactttc tagcactatc atatcctaaa acatctgcat
    10201 ctggattaac ttctgcaaat cccaactctt gtgcctgttt taaagcaaca tcatatggta
    10261 aattttcatc atacatcttt gataatataa aattacaagt cccatttaaa atagcgttta
    10321 tgctctttat attgttgcct tccagtgatt ctatcaatgg ttttaaaact ggaataccac
    10381 ctgccacaga tgcttcaaac ttgatgctaa cattatttaa gttagctaat tctataaggt
    10441 cactaccttt ttcagccagt aaatctttat tagctgtcac tacatgtatt tttttattta
    10501 acgctcttgt tacataatca aaagctggat ttaatcctcc aattacttca actagtatat
    10561 caatatcctt gtcaaatata tcttctatat cagtagttat cttatcaaaa tacttcttat
    10621 acttgtgttt ttctttattt ttaactaaaa ttccaacaac ttctatatct ctttttgaag
    10681 tattattttc tattaaatca attaatccac ttcctactgt tccataccct aatattgcta
    10741 tcttcactgt aacatacccc catcattttg attatattaa attatttata tatataaata
    10801 taccaataaa aaaagcttga gtataaactc aagccatatg acgggtttat actcatcttt
    10861 cagcataaat gctgcaggat ttagcaccaa tgtataatta aatatactgg ttgccgggct
    10921 tcacagggcc agtccctctg ccactcttga taagattgct aattaaaatt tatgtttaat
    10981 agtataatac aatttcttcc aattgtcact atttttttaa cttatttccc taaaaggata
    11041 taaactatta tctaacagct cttttagttg gtttaccctt ttttgtaaca ttattatttt
    11101 tagtctttgc tttcgcctgt tcatgtcctg gaaaaagtat tttaggctct tcaatattcc
    11161 tcttgtaaat agtaaattta aaaccaatag cctgcacaaa ttcagctctt aaagcttcac
    11221 atactgcatt agcagtttct ttagtatcaa gacctgcatt ttctaatata gtaactttta
    11281 ctaattctct agttcttaac ataccatcta attgctctaa gaaactctct gtaacacctt
    11341 ctttaccaat ttgtgtagta ggctttaaag tatttgctaa agatcttaaa tacgcccttt
    11401 gttttccttt taacatattc tcacctctat aattctatac ttaaattatc tataatctat
    11461 atttaaatta attgtaaaac tcaaattcta attcataaat tttaaccaca tctccatctt
    11521 ctattcccat ttctctaagc ctatcaaaaa caccttgact ctccatagct ttttggaaat
    11581 attgaaggga ttccatatca tcaaaattta cagaatacat tattcttcta agtgctttac
    11641 ctgtaactac atacacacca tcttcaatat ctatacttaa ctcttcttca gtaccaatat
    11701 caagttctgg tctatacatt tcttcttctg aaactagctc cacatcttct acttctttta
    11761 gcattttaga aacataggct attacttcat ctatgccttg acgagttgct gctgacattt
    11821 taaatactgt atatcctctg ccttctaatt cactcttaaa cttctcaaac ttactctcat
    11881 cttctaatat atcaaattta tttgcaacta caacttgtgg cctctttgaa agcttttcat
    11941 tgtacaattt aagctcatca tttatcttgt caaaatcttc aatagggtct cttccctcta
    12001 atccagatat atctacaata tgtatcaata cctttgttct ctcaacatgt cttaagaact
    12061 catgacctaa tcctatgcct tcagaagcac cctctataat tccaggtata tctgcaagta
    12121 caaaactatc tccaaactta gtttgaacaa cacctagatt tggtgtaagt gttgtaaaat
    12181 gatagtttgc aattttgggt ttagctttag ttacaactga tagaaatgtt gatttaccta
    12241 catttggaaa tcctaaaaga ccaacatctg ctatcatttt aagttcaaga gttatccatc
    12301 tttcttctcc atctgtacca gattttgcaa aagctggagc ttgtcttact gcatttgcaa
    12361 agtgttggtt acctttacca cctataccac cttttgcaac tatagctgta tctccttctt
    12421 tttttaaatc tgctaataca agacctgtag cctcatctct tattactgta cctgctggta
    12481 cttttaatac taaattttct ccatttttac cagctctttt tcctttgctt ccgtcgccac
    12541 cattttgagc ttgatatttt ttctggtact taaagtccat tagagttcta agccccaaat
    12601 caacttcaaa tatgatgctt gctccacgac caccatctcc accgtctgga ccaccagctg
    12661 gaacgtattt ttctcttcta aatgctaccg aaccatttcc accatttcca gccttaacaa
    12721 atattcttgc cttatctata aacaaattct tcacctactt aattaaaaac ttttaattag
    12781 cattaccaaa aataccatta taaattcatc agtattataa gaaaaaggag tgcctcaaca
    12841 ctccttttat gtatattact cagctattgc tactggatat atactaactt tttttctctt
    12901 cttgtctttt ctttcgaatt taacagtacc atcaactaat gcaaataaag tatcatcact
    12961 accttttcca acattagttc ctggatgtat tttagttcct ctttgtctaa ctattatact
    13021 tccagcagtt actaattgac catcgaatct cttaacacct aatcttttag atatagaatc
    13081 tctaccattt ttagaagaac ctaccccttt tttagatgct aataattgta aattcatgtt
    13141 taacatatgg agtcaccccc tactttttta aaatttttat attttttggg tattcccgtt
    13201 taatttcttt aaccgctaat tgaaagtgat ttagtaataa ttgtgcgtct tttacatgcg
    13261 tatctttgac tatacactct atatgacctt cttctcctac tactttttca aattcaatct
    13321 tttgtaattt gtctaaagaa tttataactg caatagcatt agatgtaact gcagcacata
    13381 ctatatcata gcctatttca gcaaaatcag catgtccctt taaacaaaaa ccttgcaaca
    13441 agaaatcatc attataataa tatttaactt ttatcataac ttaaccaata actaagcgtt
    13501 tattttttct acaactatct tagtgtatga ttgacgatgt ccttgttttc ttctgtaatc
    13561 tttttttgct ttatacttga aaactataac tttcttagct ttaccttgtt caacaacttt
    13621 agcttgaaca gatgctcctt ctactactgg agaacctaat tttaattctc catctttaga
    13681 gcaagctaat acttcgttta aagtaacaac atcacctgcg ttagcttcta atttttcaac
    13741 gaataataca tcaccttcag aaactttata ttgctttcca ccagtcttta ctatagcgta
    13801 cattaaatac acctcctcgg cctcaaactc gccagtacaa ggtacttcat ttgaagattt
    13861 aaacctttac tgtgcggcat tacaattatt aattataaaa tatttacatt ttattgtcaa
    13921 ctattttatc gaaaataaca ttggttttat tgtgctttaa tgtactattt gcgtttaaag
    13981 aaatctttat attatatttt tcaccaattt tatcaattat atccatataa tattctttta
    14041 tttgttcaaa aataaaatca ttaaattcta ccattatgtt tttgtaaaca gtatgttcac
    14101 ttattctcat aatttctttt tcaatactat ctagtatata atgtacagat tttattgttt
    14161 gttcaccatc acaacatgga caagacatta aataatactt atcaatggat tctttttctc
    14221 tacgcctagc aacttctact aaaccaagtt ttgtcatacc taatacttca gcttttcttt
    14281 tatctttatt aaattcttct tctaggatgt gtaaaatctc cttttgatgc ttctttttat
    14341 gcatatcaat aaaatcgatt attattatcc cagctatgtc tctaattata agctgtctta
    14401 caatttcttt tgcagcttca agattagttt tataaacggt ttcatcaagt ttaccagttc
    14461 caataaactt acccgtattt acatctataa ccgtaagagc ttctgttttt tcaattatta
    14521 aataacctcc actctttaac catacttttt tatttaataa tttttctatt ttagattcta
    14581 ttctgtataa atcaaataca tctctatttt cctcaagaca cagtttatca acataagtct
    14641 tatctatacc tcttaaaata gacttaagtt cagagtactt atcataacta ttggtaatta
    14701 tagattcaat atcatcattc acattatctt ttacatattt agttgcaaaa tctaaagact
    14761 tatataataa tttcggacct ataccaagtt tatattcttt taaaatattt tcatacttta
    14821 atttcaactc ttctatatct ttctttattt catcatgagt gcaaccttga gcctcagtcc
    14881 ttattattaa tcctagattt tccttattta ctgccttagt aatttttttt aatctaaatc
    14941 gttctttttc atcagtaatt ttatttgata ttgtagttct atcattggaa ggtatataga
    15001 caatatacct tccagaaata ctaatctcag tgtttaattt tgcgccttta gttcctattt
    15061 cttctttatt tatctgaacc aaaatatcct gaccagattt tatagtactt ccctttttta
    15121 attgtaaata agcaagtttc ttaaatccaa tatctacaaa acaagcttct attcctggta
    15181 taactttttt tacgattcca cgatatatat tggatacagt cttcttattt aaattgtctt
    15241 caacaaaaag ttctgttaat ctttcatctt caagtactgc tgttttctgg gaccctatta
    15301 gggactcaat aactatcttt ttcacaactt cacctctcga gcttacatag gagtcactaa
    15361 ttccccatct tctaatacat ataaatctct tctcaatata tcaacatcta atgggtcaat
    15421 atcaagttca aacatctcta atatctttgg tataagtata ttagtattta aattagtttt
    15481 tgagcctgta gctatagtag cagtaagagt aatatgttca tcttctaaat ttaaaacatc
    15541 aaaggttctt atcataggtc ttatatctac ttcaaccatc ttaccttttt tattcttttt
    15601 tgttatgatt atttctttat tattcataaa gtcaattact tttcttttta caaactcttt
    15661 cgtcataggt cttttcaaat ctatattaaa caaatattct ccatagtcta tcacagaaga
    15721 aagagaaggt gtttgtctat caatttcttt tgctttgata aaatctatcc catctggaag
    15781 ttgaattgat actttattta aaaattcctc tactgataaa tcatcttctt ctatttcaat
    15841 atctacatac tcaccttgac tttctgtccc taaagccaaa gcattgccat aactcatttt
    15901 agggtgagga ttaaatcctt gagaatgtga taagtttatt tcagctcttc taaacgctct
    15961 ttgtaacaat ctctgaaggt caagatgtga tatatatatc atgtcgcctt cctttttaaa
    16021 ttttactctt attatcttac tcatattagc aaagccccct tcctatatca tgtatattta
    16081 ttccacaacc attgcagtta tgtctacaat cagaagtgat tttttctttt ttagcatttt
    16141 cgtcttctct aattaagaat tttttactaa tacctacatc tatatggtcc caaggaaata
    16201 cctcttcata gtttctattt ctatgtgcat aaaaatctat agaaagatta ttcttttcca
    16261 tagcttcttt ccatatatct aaattaaaat gttctgccca tccatcaaat ttagcaccta
    16321 gtctaaatgc atcatatata acttttccta ttcttctatc gcctctagct actactgctt
    16381 ccatcaaact agtctttgaa tcatgataat tgtattttat attgttattt cttaatttat
    16441 ttactaaatg tctctgctta ttaataactt cttctgtagt atcttgacca tgccattgga
    16501 aaggtgtaaa tggctttggt acaaatgtag aagtactcac tgtaacacta aaacttctct
    16561 ttagctttcc tccatttact tttctataaa tatcaataac tttataagct aatttagcta
    16621 taccatctaa atcttcataa gtctcagttg gtaaaccaat cataaaatac aacttaacac
    16681 tattccaccc catctcaaaa gctctttctg ttgcattttc caaatcttct tctgtaacac
    16741 ctttatttat aacatctcta agtctttgag ttcctgcttc tggagcaaaa gtaagtccag
    16801 attttcttac ttgttgtatt ttatcagcaa tttccattga aaaattatct aatctaaggg
    16861 atggaagcga aatcccaata ttattagatg catattcatc taccaaataa tcagtcaact
    16921 ctgataactt actataatca ctcgtactaa gtgatgataa tgatatttca tcatatccag
    16981 tattcttaac taatttatct aatatttctt taagtctttt aacactcttt tctcttattg
    17041 gcctgtatat catacctgct tgacagaatc tacatcctct agtacatcct ctaaataatt
    17101 ctagtactat tctatcatga acagtatcta tataaggtac tattagtttt tctggataat
    17161 ctacagtctc aacatctttt attatccttt tagtaggatt tttagtaatc ccttctctat
    17221 taggagttac actttgaact gtaccatctt cattgtactt gacatcataa aaacttggta
    17281 tgtatactcc ttctatgcta gatattttat ataaaaaatc ttctctagtc gttttatttt
    17341 tcttccattc tttatactca tttactactt ctaaattaac ctcttcacct tcacctaata
    17401 ttactacatc tataaaatct gctaatggtt cggaattata agcacaagga ccaccaacca
    17461 ttataaatgg gtcttccaaa gttctttctt cttttaatat tggtatattg gctaaatcta
    17521 atatatttaa gatattagtg tatgaaagtt catattgaag tgtaaaagtg acaaaatcaa
    17581 agtttgttat aggctctctt gactctaatg caaataatgg tatacttttt tctctcatta
    17641 tattttccat atcaactgca ggagaataca ctctctcaca aaatacatct tcatccttat
    17701 ttattacatc atataatata tgactcccta agtgactcat accaacttca tataaatctg
    17761 gaaagcaatg tgcatatctt atcaattcac tattactagt atctttatga attgaattta
    17821 tttcatttcc aagatatcta gcaggctttt ctactttttt taagattttt ttcaagtcta
    17881 ctttattcat ttattaaaat tcctccaaac aagctcttta tttttattct tatttataag
    17941 tagtattata cacgataaaa tattttctat caaaaatata actaaaatat tgaatttaaa
    18001 atacatatta ttcacaaaat agaatagcta aaaatattta agaatatttt ctattaaatt
    18061 tttattgaaa tacaattttt ttacaaagta tgatatatta taaacataaa actattgttt
    18121 tacatgactt atcatgacat cttttgtttc attcacctca aaattgggta tgttacttat
    18181 ataatgataa attttaggag ggttaaaaat gagtaaagtt tttgaagtaa aaaaagatat
    18241 ctactttact ggcgtagtag atgaaggttt aaaagtattc gacataataa tggaaactga
    18301 gtttgggaca acttacaact cttatttaat caaggacgaa aaaacggttt tatttgacac
    18361 tgtaaaggca aattttaaag atgagttttt aagtaattta tcagaggtta ctgatatagc
    18421 taaaattgac tatgttgtaa ttcatcacac agaaccagac catgcaggta gtttaaaata
    18481 cttattagat ataaatccta atatagaagt ttattgtact aaagctgcta aactatactt
    18541 agatggtcaa ataaatagac cttttaactg tcatgtaata aaagatggtg aaattttaaa
    18601 tatcggtaaa agaaatctta gatttataac tgctccattc ttacattggg ttgatacaat
    18661 gtttacttac attgaggagg acaagactct tttaacttgt gatgcatttg gttgtcactt
    18721 tgcaagtgtt gatgcagagg tagtgaatag tgaagattat ctaaaatcag ctaaacacta
    18781 ctatgattgt atagttaagc catttgctaa acatgtttta agtgctgtag ataaggtggt
    18841 aggactaaac atagaatttg atactatatt gacttctcat ggtccaatgc ttactaaaga
    18901 cccaatggct gctgttaaaa gatatgttga gtggtctaca gaagctgtta atacaactaa
    18961 tcaaaatcaa gtttctatat tctacttatc agcttatagt aatactttag agatggctaa
    19021 aaagataaaa gaaggacttg ataaagaagg tgcaaaggct gaattatatg atttagaaga
    19081 tatgacatta acagaaatgc acgatacatt agtagtgtca aaagtaatat tactaggttc
    19141 tccaactata aacaaaacta tggttaaacc tatgtgggat ttattctctg ttatagaccc
    19201 aatggctaac caaggcaaga tagcaggagt atttggttca tttggttgga gtggtgaagg
    19261 tataactatg gctgagactt tacttaaatc tatgtcattc aaaatgcctg tagaatctct
    19321 taagaaaaaa ttcttcccta gtgaagagac attaaaagag tgtatggcat ttggtgcaga
    19381 atttgcaaaa ttagttaaat agccattaat cacacataat attatttaaa ataaatgatt
    19441 ttatatttaa aaataaatta aaatggagtt gtctcaaaat taatttttct aatctaattt
    19501 taagttcaac tcctttttta tttcccaaaa tgactaatat aatgataaat gcaccctcac
    19561 caagagggta cattatttat aatcttttct atttgtatac ttgtatattt atattaattc
    19621 acatatctag catatcttac ttgccctctt ccagaattag gttctatttc accaatttct
    19681 attttaataa ttacattatt gtttttacac ttttttgata attctgctgc agaaaggttt
    19741 ttaccagtaa aatctaaaga aaatggctta tcatattcaa aaggatactc aacaggtaca
    19801 ccatctggag ctaatgcaac cataccatat ggtgtattca taaaccctat tacagaaact
    19861 gtatgccttg atgggtctaa atttgaattt ttgcttgtaa acttaattgt atttattgat
    19921 gagttgatta aactacacgg aactccctca tacctttcaa ttttgggacg tagattattt
    19981 ccataaactt catcaagtat tgcttcttct tgatctgcta tcatagtgtg attcccaggt
    20041 ccaactggcg cagaaggctt agctggcgta ggtttcttaa cagttggcgt tggattctgt
    20101 gtctttactg attcaccaac agctggatag gctttcttgt caaatggtaa tgggtgagta
    20161 agactcttgt atatgatgtc tgctcctgct gatttgttgg catcaatatc tacatgatac
    20221 aaacgtccat cctcaaaacg aataagattc cactgatggt catttgttgt actatgtaca
    20281 taataacatt caattcccat agcatcacat aaagctttca agctcctaca cattccagaa
    20341 caagcacctt ttttagtaac caatgtataa gcagtattgg ctccctctgc tgcgttccag
    20401 ttaacatatg ttgtgttgtt tttaatgtga ttataagcaa ccctaatctt agcatctgtg
    20461 gtcatgttct ttgtaatttt cttgttcata aagtctgctg ttgcttgtgc taccgaatta
    20521 agttgagctt gtgataactt tggaccatat atactgttgg ttccagctac atagcttttc
    20581 ggtgtctttg cagtaacatc tttagctgtc ataccataaa ctgttacact catacatgag
    20641 gttaaaacca tcgttgcaat caatagttta gtagctaatt tcctgatttt tttcatatta
    20701 gcattctcct ttataatata ttttactttc aattccctac cattaattaa gttcatttta
    20761 gatttaaaat atggattatc aacatgtgtg catagcaatt cacgtggtca tagaatattt
    20821 agatttcttg gaaaatctgt tctatatttc ctatatagtt cgtacacaat ccaactcaca
    20881 aacctgcatt tttgatatca tcacaataaa atgataataa ttaatatatt caaaaatgtt
    20941 ggtctgtaac aggtttgtca attttctaat tattggtaat gacgagagtg aggagaattg
    21001 tcaataatac atttaaaatt aaaattgtat acacttcata cattctcccc taacaacatt
    21061 atacagatta taatttgtat attcaataca ttttttggaa ggtataatta tatcaaaata
    21121 tgtgattatg tatagataca atccactatg gagaaatata aaagaaaaga gtataacaaa
    21181 caataaaaaa taagatgatt caaattttat tttgaaacat cttatttact ctacaaatta
    21241 aaattatttg gtgaattatt taattattat tttttattaa agaaatttta aatcttaata
    21301 taaaatacgc tattatacat aataatccaa atgcaaatgc tactggaatt aacatctccg
    21361 attcaaaata aaagaaatat tctaagaaaa tatctggatt tactatattc ccattcttgt
    21421 ctaaaaaatc ttttccatta tatcctaaat gctgtataaa attacttatg ttattataat
    21481 ctgcttccct ctcatatacc atattagcat tcaatccaga agaacttaaa ttagtgtttc
    21541 catctttcat atctattaca tatagtctaa gagctttgac tttactatac ttatctttat
    21601 caagtatttt ttcaagttct aacttatatt caccaatatt tgtcatatca tgtctttctg
    21661 ccaattgctt tatttctcca tcaagttctt ttcctaaatt atacatatta tgttgtaaac
    21721 tattattgta ataccacata aatccagaaa ttaaaaatgc aattatactt atgtaaccta
    21781 atactttttt aaaccccatt acaattgatt tatgcctatc caatgataaa gatagttctt
    21841 ttattatatt acataattca tactgcattt catcaccatc atcaaatctt tcaattgctt
    21901 ttttacatgc ttcttcttca tctaatcctt ctaatttaaa ttcatttgca gattctataa
    21961 gatggcatct catttcctgt tttaattcta tagtactttt attgtcacat tttttatata
    22021 gtttatctaa atattcatct attagtttca taaattaatc cacctctccc aaaaattgat
    22081 tcataacctt tttaataaat ctccattctt gtttctttat ttctaaaaaa tctttacctt
    22141 cattagttaa attataatat tttcttcttc cacctgaact ttgttcattg ctataataag
    22201 atttaattaa atttttagat tccattcttt taagtgcaag atacattgtt ccttctttta
    22261 attcaaactc acttctttct cttacttgct ttgcaatttc atatccataa caatctttct
    22321 tttctaatat agaaacaatt aatatatcga tataaccttt taacacttct ttatttaact
    22381 gcattatgta ccaccgcctt ttcacctact actctataat gtatagtact tatatttact
    22441 ataataatac atagtactct ataatacaag gtttatattc tacaatagac ttaaaaataa
    22501 taaatagctg tatattagta tttatagatt aaatactaat atacagctat ttatcaaatt
    22561 ttaaaaataa atttttgttt tattaatgtt gtcgtaacaa catttacttg gttgaaatag
    22621 tattacctat aagtttaaat atatataata atagacttaa ttctatttca tattattaaa
    22681 atagagtaat agtttaaatt ctactactct atctataatc tatttcctaa ttatttaatc
    22741 tcaaatttag ctcctcatca tttaaatctt tcataagatt tctacaggta ctaggtttat
    22801 tgcaacagaa aaactagggc attaaacact tatatatctg tttctttaga ctgtaatatt
    22861 aatatttttt aaatacgttg acttttgctt tttctaactt ctctccatga tagttctcct
    22921 ctatcaagag cttttataaa tatttctgct gaagctagat ttgtagctat tggaacatga
    22981 taaacatcac aaagtcttat taacgcttgt atatctgttt catgagcctg agatgtcaat
    23041 gggtctctta aaaaaataac taaatctatt tcttgtgtta ctattaaaga acctatttgt
    23101 tggtctccac ctaaaggacc agatgctaat ctatttatat ttaattcagt ttcatccatt
    23161 attctttttc ctgtagttcc agttgcatat agtccatact tttttaaaat tgattcataa
    23221 cctatacaaa atccgaccat agtgtttttc atttggtcat gtgctactaa tgctatattc
    23281 atatatctaa tctcctcaat ttatgtttag atgtatttaa atttagaaat ttattttctt
    23341 tcttctcata cacacattta gtactaatcc taagtttgct aaagatgtca ataacgaact
    23401 tcctccataa cttacaaaag gtaatgttac tccagttact ggtattaacg caaccgtcat
    23461 acctatattt tggattatct ggtaaccaaa cattcccata acaccaacca ctatgagggt
    23521 tccataaaaa tcttttgcat ctcttgcaat tgctaaaagc cttaatagga atatcataaa
    23581 taagattatc aacactgcca ttcctattac accaagttct tcacctacaa cagcaaatat
    23641 aaaatcacta tcttgtacag gtaaaaaatc ttcttgattt tgacttccat tgtaaagtcc
    23701 tttaccagtt acgcccccag aaccaattgc aatcagagat tgcataactt gatagtttcc
    23761 ttttagagtt acatcttctg gatttagaaa agcttctatt cttacctttt gatggtctgc
    23821 catcattaaa tacatcagtg gcattgacac taatagtatg attattcctc tttttatcaa
    23881 ctttgagcta agacctgctg tgaacagcat tgcaaatatc atacaacaaa atacaattcc
    23941 tgttcccaag tctggttgtg caatcaataa tccgataaat ggaagagaat aaactacaac
    24001 aggcataact tcctttaacg tatttaattt atcctttttg gattcaagta tctttgcata
    24061 acttagtaca aatgttaatt tgactatttc agatgtctgc aagtcaagtg gtcctaagtt
    24121 aatccacgac ctagctccac cttttactgt cccaattcca ggtaataaaa ctatggctaa
    24181 caaaataaga cttattatat aaagcgcttt ataatacctg cctagaagat tatagtcaaa
    24241 aaataatatg actataatca ttcctatacc aagtacaaaa gctaatcctt gtttaatcaa
    24301 ttgattatat gaacctgttg aattagcatg tgttgcacta ctaagtataa caagcccaaa
    24361 aataaagata gctaatactg taactataag tttccagtct aactgtttta tcaacttaat
    24421 tgtcgactta taattaatat tgattttttt caaagaatca ccgtctttct atctttaaac
    24481 atataattaa ataaaagggg catataccaa taaggatatc ccccttttaa gcactaatta
    24541 catacatcta tcttttatat tctttagtgg tatattagca actaatgcag atacaggttt
    24601 gtcatcatgc tcacctctgc atttagacat ttttatttca agaccatcat cttctatttc
    24661 tgcataatta gctattactt ttaaaatgtc tgtttttatc atctctaaaa gttgtggtga
    24721 acaatctact ctatcatgaa ctaaaactag ctttaacctc tctttagcaa cagatttact
    24781 agttttagcc tcgttagaaa aaactctaaa taaatctaac acagatgtat cctcctttgc
    24841 tacttagcca tgctaaacat ttttttaagt ctaccaaaga atccatcttc aacttcaaga
    24901 tcaagtagag gaacttcttc atttagtatc ctttttgcga tatttttgta tgcttgacca
    24961 gcaagtgact tagaatcaag tatagctggc tctcctttat ttgttgatat aattatgctt
    25021 tcatcatcag gaacaagacc taacaaatct attgctaata tttctattat atcttgttta
    25081 tccatcatgt ctccacgctt aaccatatca tttctaattc tatttataac taatcttatc
    25141 tcttttattt catttgcttc taatagacct attattctat cagcatctct tactgctgat
    25201 atttctggat tagtaactac aatagctcta tctgccccag ctactgcatt tttaaagcct
    25261 tgctcaatac ctgctggaca gtctattatt atatactcga aagattcttt tagtttctca
    25321 cacagatcaa tcatctgctc aactgagaca gcatttttat ctctagtttg tgctgctggt
    25381 aataaatata gattatcaaa tcttttgtct tttattagag cttgcttaag cctacaagtt
    25441 ccttcaacta catctactat gtcataaact attcgatttt caagacccat tactacatct
    25501 aagtttctaa gtccaatatc tgcatccaca actactgttt ttttattttc taggcttagc
    25561 gcagttccta agtttgctgc ggtagtagtt tttccaaccc cacctttacc agatgttata
    25621 actataactt cgctcataat actaccccct atttttcttt ctatttgtct aactttgaca
    25681 aatagctttc gattacaatt cttccattac ttacaaaggc tatttctggg ctaatttctg
    25741 attcattttc ataattttct tcatcatctg gagcttctgc aatattatct gctatttgta
    25801 atattttagg attaagattt ccagcaacaa catatgcaaa ttcattgcct tctgcacctg
    25861 catgtacaaa accttctatt ttacccatta caaaaacatt acctcctgct acaaccttag
    25921 caccagcatt tatatctccc ataacaactg tatttgattt tgaaaggact tttgaaccag
    25981 gtttcatatc attcaatata actacatcac cttcaaattc aatattttca ccagatctta
    26041 gggtattgac atattttgtt ggaaaattac tattttcttc aattttttga tcttcaacaa
    26101 attccacatc aaatctagaa gtaattcctt ctttaagttc tagaatctcc atgtcagtta
    26161 aacaatcact attaatttta ctaattttag ccccattaaa aaagccaaca tatgcttcca
    26221 atttgtttat tattttttcc tgtatttcct caaatggagc ttctcttttt atatttacta
    26281 ttatccctct tttattaccc ttgaactcta ctagttcttg actacaaatt tctcttaaag
    26341 acataacaac ctccagagtg atatatcatt tatattcttc aaatacgctt taaacccttt
    26401 tattttttct atataaagct aaagtttata catagattaa gctatctatt aatttgtgac
    26461 tcgaaattta tattttcgtc agaagaattg ttaacatcat tcgtcttgtt gtcattttta
    26521 ctattagttg gctctaatcc catataagtt ccaataactt ctctagttgg taaaagtgag
    26581 aatacacttg aatcaccttg aggaattaca catacaacag ctatttctgg gtcatctgct
    26641 ggagcaaaag caacagtcca tgtaaaagaa ccataatctt gtttaaatct atctatttgg
    26701 tcatctgtta tttttggatt taattctttt atagcttttc ttagatatga agaattcacc
    26761 ttatcagtgt cctctaatct aacttttact ccatcttcta attcttcctc taatttcttt
    26821 ctttcttcgt ctttcaaatc tttattttct aatttctttt ttatttcctt ttccttagct
    26881 aatgaaagct ctttttcttt ttctgctttc atcttatcag ctagtttaat cgcatcattt
    26941 aggttgacat tataagatga catatgactt tttaaatatt catactcgtt atctgtaggt
    27001 attttcccac ttttctcagc tgtaccagtt tttgctgcta catctattgg aaaatcagca
    27061 aaagcactct tcgctgtacc ttgtcttgca accaatttca taccttttgt taattctttt
    27121 aagttatctg gatttttaaa aggtattttt tcgactttct tctggtcatt aattttaact
    27181 gatgaataat cacttgaaac agctctatca actacagata attctactaa attacctcca
    27241 tttgctatag cagctacata tcttgatatt tgagctggtg tataagcatt ttcaccttga
    27301 cctatagcta agttaaatgt atctgcagta ctccattttg caaagttaaa ataactgaat
    27361 actgctaaat ctgctacttc ttctattcta tcttctttaa cattcatttt ctttagccta
    27421 ttcattgttt cgactctacc aggagttttc ttttctgctg cccagcttac aatctcattg
    27481 attcttttct catattcttt aggatttttt tctctagtta tatcaacaaa atcatttgcc
    27541 atttctcttt ctaaatttga ctttagaaga gcttgtgttg atttcaattt atcttctgtg
    27601 ctaggaactt tacctgctct ttcttctact tcatcttgaa gccctgtatt ttggtcaagc
    27661 ccaaataatt ttgcatactc aagtatttta tttgcattca tatctatacc aatgcttttt
    27721 ccatctggcc atgttttacc tgtaccaatt gttgccatat atatattaca agactcttgt
    27781 atcgctttat ataagtttgt cataccatgg tttcctctac catggttcca tacatagtca
    27841 ccaaaagatt ttttacctaa cattataacc ccagggtcat ttatagtaaa gtttggatcc
    27901 aaaccatttt ctaatgctgc cattgaagtt agcatcttaa atgaagaacc tggctgaaat
    27961 tccccttgtg taaccaagtt taaaagtgga cttcctgcta gtaagtcatt tggatttttt
    28021 ggttgaagtg ctttataatc ctctgtagaa ataccttttg caaatttatt tgggtcataa
    28081 ttaggataac ttgatgaagc taatacttct ccatttttaa catcaatagc tataagagct
    28141 gctgactgtg cttttcctgc atatgcacta attggtttgt ccccaaattt acttttaaaa
    28201 gtacctcctt tagaagcaac ttcgattatc tgttttaatg cattatctga aacttcttgt
    28261 aaatctttat ctagtgtaag atacacagta tctcctgatt taggtttttt agattcaatt
    28321 tctttactga ttctacccaa tgcatcaact ttaaccattt tataaccatc agttcctctt
    28381 aatctacttt cattactctt ttctactcct gcaagaccta ccatatctcc agtttcataa
    28441 cctttttgaa ggtatgattc tatttgagtg gatggcattt ttcctacata tcctaacata
    28501 tgagaagcta atgacccatt aggataatat cttactggtt ctactgctat tgaaacacca
    28561 acaaggtcca tagcactttc ttcaatttga gcaatcgtag tttctcctac atccttagca
    28621 atagttactg gattatattg agaatatcct tttgatttta tcaaatccct tacgaccatt
    28681 atttttcttg catcttcatc actcaaactt ttatcaattt ctaatgcatc actatttctt
    28741 actttttcaa acgcttcttt ggcactcagt ttagtttctt ttatcttata actagccaac
    28801 caatctctct tatctctttc tgctgtgaac atccatttac taactaaaat aggtggataa
    28861 tatccatttt catttagttt tgcctgtaat cttgtcgcat ccaatctttt atcttcttga
    28921 gataatattc cagctgatat aagtttgtct actaagtaat aaaaactttc cttagcatta
    28981 taatcatttg gaataccatt ttctgattta tattccctaa tatctctgtc atatgtataa
    29041 tagtactttc cattttctac atatatagga aactcatcta catattcttc accatttctc
    29101 tccagcaaat ttataagttt taatgatatt tcatttgctc ttgaatgctt atttgcatct
    29161 ttcttattaa tatcgttacc tgaaacttga acagtaaata agtttttatt tcctgccaac
    29221 agtcttccat atctatcttt tatttctcct cttggagctt ctattgccaa ctttttatat
    29281 gttttattct cagctaactc attgtaatat tcatatttaa atgtagtcat atagattatt
    29341 tttactaaaa tagctaaaaa tatcacgctc atgactatct taattatttt tagtctatca
    29401 acttgtttat tttcttccat gaaatcacca actaatcttc tttaagtttt aaaactgctc
    29461 ttttagataa gcgatatatt actaaaccaa ttaaactatt cactattggt gctactagta
    29521 gaccttttac aaaaagtgtt gatatgttgt agctttgata aattatacta gatgtaccta
    29581 tattgacaat tgaatcaatt aaactgccta taaaaattaa aacgaaagta ataatataac
    29641 tacctttata tagctgatct ctcatgtatc caattgcata tgcaataata aacaaaatta
    29701 atgcatttac accaaaaatt ccaccaacgg ttatgtcttt aataagccct attattgctg
    29761 ctataatccc accttctaat tcatctaaat aaagagagat tatggttaca tatataagaa
    29821 ctaaattaaa gcttatgcca aaaatatcta tataatttgt tatactattt tctatagtca
    29881 taagcacaat ccccaacaga caaagtaaaa cttttttcat tgtttttatc ccctttatcc
    29941 tatatttctt ggttctatga ctacaacgtc atttatattc ttaaaatcaa cataaggttt
    30001 tacaactaca tattttaatg acttatcttt atcatcaacc accttttcaa cttcgccaat
    30061 tggtatacca tctgggaaga atccaagacc tgatgttgtt attatatctc cttgaattac
    30121 attatatgat gagtcaaaca tatatccttg caaatatcct ttactattat aactatcttt
    30181 attatctaaa gtagtatttt gagtaattgt acctttagca ttggcatcct ttgctagttt
    30241 aaagcttaca gatgccttag aatccaatag tgaaattgcc ttactataat tgttggaaac
    30301 ttcataaact atgccaacta acccactacc attcataact atactttctt tttttacacc
    30361 tgaatttttt cctgcaccta tgacaaaact ctcataccag tttccatcat ttttaccaac
    30421 aacacttgct gaaatacttg tcgccttata ctcttcttgt acaaagttca gtgtcttttt
    30481 taactcttct agcgattctg ttttatctag tttggcattt aaagctatca tatctttttt
    30541 aagtttttca ttttcttctt ccaatttttt taccttttta gaattatctt taaaatttgc
    30601 tacatcttta aaaccatttt tgataaaaga aaatccatca tttattccct tacctacact
    30661 tgtaatagca tctgaagcta ctcctaaatt tactggacta ccactagaaa atttaccaat
    30721 tgatataccc acaattccaa ttaaagtgat agcaactacg cccgttgcta tcactttaac
    30781 attaatcctt tttttctcat ttttgttctt gtcaaatctc aaggccatca ccaacttcta
    30841 attcttagta ttcatcatta atactttttc aaagatttct tggtcttcaa cagatttacc
    30901 tgttccaagt gcaacacaat caagaggtgt ttctgctatt tgtacagaca taccagtttc
    30961 ctgtgtaata agcttatcaa gacctctaag caaagcgcct cctcctgtta gcattattcc
    31021 gttttccatt atatctgagg ctaattctgg tggagttctt tctagtgtag attttattgc
    31081 atctactatt gaacttacag gttcttttaa tgcttctcta acttctgtag agcatatttc
    31141 tattgtttta ggtaatcctg agattaaatc tctacctctt atttgcatat ttatttcttc
    31201 atcatcttta aatgtagaac ctatgttaat ttttacattt tcagcagttc tttcacctat
    31261 cataagatta tattcttttt ttacataagc cactatagac tcgtcaaatt cgtctccacc
    31321 tattcttata gatttagcag taacgattcc tcctaaggat attacagcta tttctgaagt
    31381 acctccacca atatcaacta ccatattacc ttctggttct tcaactttta atccagcccc
    31441 tatagccgct gccattggct cttctataag gaatgcatct ttagctccag cttgtcttgc
    31501 agcctcttct atagctctct tttctacttc tgtaactcca aaaggaacac atatagctat
    31561 tcttggactt acaacacctt ttttatcagc cgctttttgt ataaaatagc taatcattga
    31621 ttgagttatg tcaaaatcag ctattactcc atctttcata ggtcttatag ctactatatt
    31681 tcctggtgtt ctacctatca tttttttggc ttcttcacct actgctaata cctctttact
    31741 atcatctctt attgcgacaa ctgatggttc tctaacaaca ataccttgtc cttttatgta
    31801 aactaatgta tttgcagtcc ctaaatctat tcccatatcc tttgtcatct tattaaaact
    31861 aaaaaaacct tttttttctt tctttttttc cttagccatg attttactcc ttcctactat
    31921 taagaatcat gtttaaaaca ttctcctatt attttatcac atataaagtc aaattatcat
    31981 attttcttta aagctaaagt ataatccatc tccaataatt atatggtcta ttatttctat
    32041 tccaattatt tctccacatt taataagtct tgatgtgata tttttatctt ctcttgatgg
    32101 ttctacactt cctgaggggt gattatgcat cactattatc ttacttgcac ttcttcttat
    32161 agcttcttta aaaacctctc ttggatggac taatgacgag cttaaagtcc ctatagatac
    32221 atctacatca gatattatct cattttttgt gtttaaaaga actgctttaa aaacctcttt
    32281 ttttaaatac cttaggctat ccatataata cctctgtata tcccaaggat tccttatttt
    32341 atactttata ggtttaaaac tagctactct agagcctagt tctaaagctg ctttaatttg
    32401 ggttgatttt gataacccaa ttccatctat attacacagc tcctctattg tcatatcttc
    32461 taaatgtcta ataccctgaa tatctctatt tattatatag ttggctaatt caatagcatt
    32521 tttattcttg ttgccagttc ttaaaagtat agccaacaac tcagcatttg ataagctttt
    32581 tacgcctttg gcaagcatct tttctctggg tctttcctct ggtgccattt cttttacctt
    32641 aatggttgaa ttaaatgact ttttcagata aatcacactc cataaaaaag atttatacta
    32701 aaatattttt ttaataggtc gcctaacctt gaaattggaa gaccaactat attaaaataa
    32761 tctcctctaa tttcttcaac taacaaagct ccataaccct gtataccata ggctcctgct
    32821 ttgtcaaatg actcattagt tttcagataa tcctcaatat cctgctctga taacgtttta
    32881 aatttcacat tgctgattac atagtcaatt acctttttat cttcgcacaa gtttattaag
    32941 ctaatacctg ttatgacttg atgctctctt ccagatagtc tttttaacat atctcttgca
    33001 caagactcat cttttggttt tcctaaaata gcattgtcta aaacaacaac tgtatcagct
    33061 ccaataacaa catcttcatt atgttcagat gctacagaca tacttttttc aaaagctaat
    33121 ctcataacta aatgttttgg tgtttcacct tccaatataa tctcatcaat ttcattttta
    33181 attatatcaa atcttacatt cgtattctct agaatttctt tccttcttgg agaggctgat
    33241 gccaagatta tattcattta ttcacctcat ttgtacgtaa tttgtaccta tttagtctat
    33301 cactatattg taaaaaattc aacagaaatg tcgaaccttt tttgttacac tattgttata
    33361 tttattacca ttagaataaa tatacataaa atagaggtat ggaaattatt ccatacctct
    33421 gttttatgta ctcattagag atatggaaat tattccatat ccttattttg tccatattac
    33481 aaaattttaa tagctttctt tggacatttt tccatacata aatggcatcc tacacattta
    33541 tctgcatcta ccttatgttt ttcttttaat tctccctcta ttgcatcaaa cttacattgt
    33601 tttttgcaca ctgtacatcc aacacaaagt tcttggtcaa tagtaacttt ctttttctta
    33661 gttatgtcac ctgatattac ttttgtaggg cattttgcta cacattgcat acaccctaca
    33721 cacttattag ggtctatctt agctattttg tcttcaaata ttattgcatc aaatttacaa
    33781 gcttttacac acattccaca gccaatacat ccagcagtac atttttcctt aacagcttta
    33841 ccaaactctt tgctattaca ctctacaact acttcttgac tttctggttt tgtgattatt
    33901 atacccttag gacaaacttc tttacatttt ccacaattta cacacttttc ttcatctatt
    33961 actgctattc catcaactat agaaatagca tcaaatttac aagcatcctt acatgttcca
    34021 agacctaaac atccaaattt acacatctta gcacctgagt ttaaaacatt tgctgctcta
    34081 caatctgata ttccttcata ctcatattta tcttttgcac ttgaacaagt tcctttacaa
    34141 ataacttttg ctacttgttt ctcacctgct tcagcactta ttcccattat ttctccaact
    34201 tttgcaccaa catctgctcc acctacaggg caaccattaa ctggtgcatt gccttcaact
    34261 atcgcatttg caagacctcc acaacctgga aatccacaac ctccacagtt ggctcctgga
    34321 agtactccta gtatagcttc cactctctcg tctacttcta cagcaaactt tttagatgcg
    34381 aaatctagta ctatcccgaa gattaagccc ataattccta aaactaatac agctgtaagt
    34441 atcaccattt tcacccctct tttttatagc tttataagtc ctgtaaatcc taagaaagct
    34501 attgacatta aacctgctga tataagcgtt atagggaaac ctttaaatgc ttctggtata
    34561 tcagctaact ctagtctttc tcttatacct gcgaatatta ctattgctaa agtaaatcca
    34621 gctccggctc caaatccatt tattattgtt tctactaaat tataactttt ttgaacatta
    34681 actagagcta taccaagaac tgcacagttt gtagttataa gaggtaaata aactcctaat
    34741 gcttgatata aagatggact catcttttga attaccattt caacgaactg aactatagaa
    34801 gctataacca atataaaagc tattgtttgt aagaatccag ttccagtttt tactaataaa
    34861 atctgtataa aataagttat aattgaagct agagttaaaa cgaacgtaac cgcaactccc
    34921 atccctactg ctgtatcaac cttcttagaa actcccaaga aaggacatat acccaagaat
    34981 tgagatgtta taacgttatt aacaagaacg atacttaaaa ataaaagtat taaattcatt
    35041 tattacacct ccactatgct tttttacttc ttaatttatt aaatcctgca aataagaatc
    35101 ctaatgttaa gaatgcacct ggtggtaata taaatattaa tactggttgg aaagatgctc
    35161 caaataatgt cattccaaat aaactaccat ttccaagtaa ttctcttact gcacctatta
    35221 ttgtaagtgc aacagtaaat ccaagacctt gacctacacc atcaactatt gaaggcatag
    35281 ctcctgtttt gaaagcaaaa ctttctgcac gagctaatat taaacagtta acaactatta
    35341 atggtatata tataccaaga gccttatcaa gagcaggaac atatgctttt aaaagcatac
    35401 ctactattgt aacaaatgta gctataacta ctataaatat aggtattctt atcttatctg
    35461 gtgtaatttt tcttattaaa gatataacta aatttgcaca tattaaaact gctgctgttg
    35521 aaagacccat accaattcca tttattgctg aagttgtaac ggctagtgtt ggacacatac
    35581 ctataacttg aacaaatgtt gggttctcat ctattagccc atttttaaat actttagcta
    35641 aattcataat taaccctcct tatttattaa gagcactatt gaaaacatct atagcagcat
    35701 ttactcctgt agtaactgct gtagatgtaa tagttgcacc tgatattgct aatatttgat
    35761 tatctgctgt tgtacttcct tttgctactt caagaggctc agcagttttt cctttgtatt
    35821 gacccttaaa tgcatcatcc ttagcttttg ctccaagacc tgctgtttct gacatattac
    35881 caatgtcaac acctgtaact tgaccttcag atgatatacc taccataact tcaatttctc
    35941 caccatatcc acttggttta gcttttaaag tatatccaac cacttcagaa ccatctaaac
    36001 cttcatacac ttcagctata agaccatctc caaggtcttt atatgtactt ttatccattt
    36061 ctttaaattc ttttgcttct ggaaggactg cttttctaag ttcattattt tcttgtatat
    36121 ttctttgttc tattactgga gctgtaacct gattagtagc tccaagagct aatgcagcta
    36181 ttgcacttat agcaagtaaa gtaccaccta atctcaccat actgttcatt atttagccac
    36241 ctccccaaat actctatttc taacaaactt atctataagt ggagcaagac agttcactaa
    36301 tagtattgag taagatacac cttctggata tccaccatac attcttataa cagttgttat
    36361 aagaccagct aatacagcgt atattatttg acctttttta gtcataggcg aagttgtata
    36421 atccgtaagc atgaagaatc cacctaacat aagtcctcca gcaaacagtt gatatattgc
    36481 gaaagttata ttaaatccac ctaaaaggaa tgttaatata aatacagttg ctatgtaaaa
    36541 tactggtata acataattta ttatgccttt atacattagg tatactccac ctaataataa
    36601 taatattgct gatgtctcac ctatacatcc accaatattc cctatcatca tgtcagcaag
    36661 actaattcca ttgctagaaa ggtctgccag tcctgctgct ccatttttca aaaagcttaa
    36721 tggagttgct gtagtaactg catctaaatt tttacctatc cagttaacac ctggttgagt
    36781 ccaagcagtc attgctactg ggaatgatgc taataaaaat gctcttgcag caagtgctgg
    36841 attgacaaag ttacatccaa ttccaccaaa taccatttta actactaata ttgcaaatat
    36901 tcctcctact agacacatcc accaaggaag tgatgctggt acgttaaatg ctaataataa
    36961 tcctgttaca acagctgaaa aatctcctat agtacttttt tgcttcgtaa atttttgata
    37021 taaaaattca gtacctactg taccaagtat acaaaaaaac atagcactca aagcattaag
    37081 tctaaagaag tatactcctg ctactgctgc tggaaggagt gctataataa cttgtttcat
    37141 tatatatgaa gtatcttcat tacttctcac atgaggagaa gatgatacta tcaacttatt
    37201 ttccatcgtt tttccccctt aactttcttt atttctgagc agcttgcttt cttctctttg
    37261 ctcctatttc tctctttgct gatcttatag attgaagtaa tggtcttctt gctggacaaa
    37321 taaatgaaca agacccacat tctatacaat ccattgctct atgatattca gctgtgtcat
    37381 agtcatcttt taaagaatat gcacttatga aaagtggttg taagaatgat ggacatacat
    37441 ctgtacatct tccacatctt aaacagtttt gaatatctgg agtacgtgat tcttcctcat
    37501 ccaagcataa aattcctgaa gaacctttgt tagtcgctat ttcagtagta tattgagcta
    37561 ttcccatcat aggtccaccc attataacct taccaatctt cttatcttct ttaaatccac
    37621 cacattgttc tattatttct gaaactaatg ttccaacttt tgttattagg ttctttggct
    37681 ctttgatgca actacctgtt attgtagtga ttctttcaac caaaggcata cctgttttaa
    37741 tagacttagc tatttgtgct gctgtggcaa cattgtcaac aactgcacct gctgctattg
    37801 gtaatccacc agatggaact tctttgcctg tacacgcata aataagttgt ttctctgctc
    37861 cttgtggata tttcacttga aggccaacaa cttcgatttc actatagtct ttagctacat
    37921 tttgaattgc ttctatagca tctggtttat tcgtttcaat tcctataaat ccttttttga
    37981 catctaatac cttcattaat gctcttaaac caaacacaac atcttctgga ttttcaacca
    38041 ttaatctgtg gtctgcagtt aagtatggtt cacattctgc accatttaat ataactactt
    38101 ctgccttgct atctggtgga ggagatactt ttacatggtt agggaatgta gctccaccca
    38161 tacctactat tcctgcctct tttatgatac ctactatatc ttctttgctc aaatcctcta
    38221 actgaccttt tggttgaaca ctctcatgta attcttcctt aaagtcattt tcgataacta
    38281 cacattgagc tgaacctcct ggtacttcat gttgttcaat agcaataact ttacctgata
    38341 ctgaagaatg aacgttacat gaaacaaaac cttgttgttc acctattttt tgcccaaact
    38401 ttacttcatc accaacttca acaataggtt tagctggtgc ccctatatgt tgctgaagag
    38461 gaatgtaaac tatctttgga gcttgagctt tttcaagtgc ctttgtgtta gagtactctt
    38521 ttctatatgg aggatgtatc cctcccttaa aagttaagag tttcattgtt ttaccccctt
    38581 atctataaaa aaacattttt tctgccttct ataagtatac tatatatatt aaaaaatctt
    38641 aacaattgtt aaaaaaatat ccgtattttt ataatttatt ttataaatca atacctctat
    38701 attaagtcaa actgaggaaa aggattgctt aattaaacaa tccttttcat atagctttct
    38761 aaagtccaaa ttttctgtat tttattttat agaatttata aacatagagt actcctgcat
    38821 ggatgataaa agcagacttt tacttacact atatttttct tcatttgctg cttttgaagc
    38881 tgtatcaatt ttttcattca cattctttac atactctatt aaattatctt taaataaacg
    38941 catttcagaa tagtcaatct tttcagcttc ttttgatata ttttgtgata ttgcctttct
    39001 atttgtcaaa atagtattat atttttccat atctacatta ttttcagcat tcgaccaaaa
    39061 acttgattct tctttaaagt ttgttattaa tttatttaat tctttagata tactctctat
    39121 ataagcgtag ttacttgtat actctaaaga caacataggt gcatctaagt gtgataaaaa
    39181 tgcatctgga aacacctttc ttacactgct tatctgcttt ctaacatcat tttcatcaaa
    39241 agaggaatag gtctgtattt tttttactcc atccttctcc ataactgaaa aaggtatgtc
    39301 attattaact aatgatgtct gtattttttt caaatcatca ttattatcta ttgcagcaac
    39361 ttgaatagtg tacatatccc agccttctat agtagctaat ttgacttctt ctggctcttt
    39421 agtgttattt accgcttttt ctggattagt ttcttgttta tcatctgaat tggtttgtga
    39481 tttagatttt ttcccttttt ttattgaatt taattcatca gatatatctt tataagttat
    39541 atctgatgaa ttatttagaa atggtatttt agccgataca tactccaata tcttgctatc
    39601 ttttattttt gtataagaat aatagccaat tagacacaag caagcaatcg ttataacata
    39661 tttacgtaaa tcaatcttat gtctattatt attaaatcct ctgtatatcg tttttcttct
    39721 attcattagt ttgtccctcc caaaattata ttattaataa agtatatttt taagagtcac
    39781 aatttatgaa tataaataat tatttcttct aattttttaa taagaaattg tacttactaa
    39841 acaaatcttc ttgcaccaag taatacttta gaccaatatg aactagttaa attatccact
    39901 ttaaccttat taggattagt ctgagtacca ctacaatgga taaatttact atttcctaca
    39961 tatataccta catgattagt tgttccatca ccatcagtgt caaaataaac taaatctcct
    40021 ggtgcataat tccccataga aattgcactt ccaaaattag cctgttctct agaaactcta
    40081 ggaatagaaa cgcctacaga atgtttaaaa acatactgtg taaatccaga acagtcaaat
    40141 ttatcaggtc ctgaagctcc ccattgatat ggtattccaa taagagtata tgcaaaatct
    40201 acgattgttg aaccttttgc tgtagattta tctgaatttc cagtaaatga tggctttgag
    40261 ttactattag attgagaatt ttggttagat gatgaatttg gtttttcttt tgtaccttca
    40321 ttagtctcag aaatataact ggcactcacc catccaattg ttccactcga taactttacc
    40381 ttataccaac cattattttt ggattttaat tcaacaacat ctccaccatt taattttcct
    40441 attatagaat agcttgtccc aggaccactt cttacattta aactcacagc agatgttacc
    40501 ttaccattct tgccttcaat tgattcttcg ctagatggtt ttttatcaga attattagta
    40561 ctatttgaat tactagaatt attcgttcca acatcctctg atgttttaga gatatattgg
    40621 ctactagccc atccagtaac tccatttgat agttttattt tataccatcc attgctttgt
    40681 tctagtaact ttactacatc tccattattt gctttaccaa ctaatgaata gttagtacct
    40741 gcaccacttc ttacattcag tctagaactc acatttactt taccatttcc actaatagtt
    40801 gtcccacttg aagttggatt attttgattt gatgtacctt cagatgaacc acttgttgat
    40861 atgtattttg cgcttcccca tccaacaaca gaactcgata cccttacttt ataccatcca
    40921 ttagactttt ctaaaatctc tacagttttt cccttgtata attttgctac cttatcacaa
    40981 tcagaacttg gtccacttct tatattcaag gcacttgctg ttactgttcc cttttcaaga
    41041 gcacttgcat ttatggagct aacagatact gctactgccc caattcctaa agctgctata
    41101 gctttcttca ctactatcac tccccccaac aaatttttat agtcataaat tcataacatt
    41161 attatccatt tttagtccct acaatttaat gataacttat tctcttatta attgtaaaga
    41221 aattataaac atatccttaa aattaatgat ttttaggaag tatttcaatc caataattat
    41281 ctgggtccgc tataaaataa attcccatac tttcattttc aaaacatatg caatctaaat
    41341 ctttatgaag tttttttgcc tcatcaaact cctcaacttc taaagccaga tgaaattcat
    41401 tgtctcctaa attatatggt ctgtcccaat ctctaagcca agttaattct aatgtatgac
    41461 tagtaatacc atctcctaaa taaactaata taaaacttcc atcttctgct tccttacgct
    41521 ttacctcttt aagccctaaa gcttttttat aaaaatctaa acttttttct aagttagtaa
    41581 cattgaaatt gttatggcaa aaattaaact tcattttgaa atcactctcc aatttttatt
    41641 ttttttatat tatatcatta ttataaattt atttaaatca tattaagtta aaaatttgaa
    41701 tgatgatgac caattaccaa atggtggtaa attatttaaa agaatatgtc aaaaaaagaa
    41761 taagctcttt caaatgcaca aaaaatttat acccaagtta tacttaatca tgcaaattgg
    41821 cagaacttat tctttaaaac tctaactttt aagtttttct ttgataatat aatttattac
    41881 tttttttcta atatcttcag cattataatc atcttctact tctatatcca aaagttttgc
    41941 tattgacctc atatcttctc tagtctttga cctatagctt gatattaatt catcttttat
    42001 tttctctggt tctaaaagat attcttcatc tcctcttttg aaaacaacgt atttttgagc
    42061 atatgaactt ctattatagt atatatatct tgatattttt cttaaaattt gattatatga
    42121 aagtcgcttg ttaatatcaa gttttaagta ctctgaaaaa gcaaatagct ctttttttga
    42181 tttaaataat gcttctttct ttatagtcct tgatattgaa gttacacttt cttgatatgc
    42241 acactttttt aacattttta aatatactct attaagacca atactttgat tgaatttttt
    42301 tatattatta ttaataatct tatccaagtt accttcaaag tatttttttg ctcctttttg
    42361 tgatacataa ctctcaagtt ctttgtgggc catatcaagt atcatttttt ttaaatcctc
    42421 tttatatccc ctagattcca tgatactccc tcccttagct atttatagta tattcaaaaa
    42481 gctcaagaaa tgtgagtcat tacaaaattt ttttactttt tatgtatata ttaatttaaa
    42541 aggggagata atagtaatgt aaaatcaaac atactcaatc tcccccattt ttagacctct
    42601 attactcccc caatagaggc ctttttttag tttatcaatt tctattcaat tccctttagt
    42661 tcaaatccta attctgctat cacttctttt aatttttcaa tagatatatc atctttcata
    42721 tctacagatg cacacttatt ttctaaatcc acatctaaaa cttcaatacc atctatatct
    42781 tctgttaatg cagttttaag atggtttaca caatgaccac aactcatacc ttctactaat
    42841 agtttcttct tcatttaatt acctccttat accccataag ggtattctat catatagttt
    42901 atacttttta aatagaaatt aatcatttaa tttgattcat tcgattttat atctaaatta
    42961 gatattccct catatacatc aaaatcattt ggagtaattt taccttttaa tctactatta
    43021 cttacaatat agttgtttct cacagctaaa cttataaatg ttgcattatc ttttatatat
    43081 gtctgtacat ctttgtatgc tttttttgtt tcaatttcag acgtagaact tgtaagtgca
    43141 gacatatatc catttagctt atcatcagta tatccactac ttgctataat actacttgca
    43201 tctggtataa ttgatagttt ccatccaact aatgctaaat cataattttt agaattaaga
    43261 gcattttcca tatccttatc tgacagctga tttactgtac tatttattcc tatagctttt
    43321 aagttttcat ttattatgtt tgcagttttt attctctcac tattatctct gtttactatt
    43381 atctttaagt tcatttcaga aagacttttc tttacttcct ctttttctct attttttttc
    43441 ttttcagctt cttttttgat tctatcttct tctgcttttt tagcttttgc ttcttcttct
    43501 ggcgtaagct tctttgagtt ctttttagct gattttttct gattttttac tttattgtca
    43561 ttttgattta ctgagtttat atttgcatat tctaccttag caagacactc tatcgcctta
    43621 tctttattaa actctaaatc cttcatttca ctattatagt attttgattt tgaattaagt
    43681 ggaaaattaa ctggagtagc atcatccata taaccttcac taataattct atctttatct
    43741 atagagtgag caattgcttt tctaaaatta acatctttaa aaaatggatt attataatta
    43801 aataatacac actcataatc tcttccttga tattttgtta tattaaactc tttttcttga
    43861 aacttgctta aatcatttaa tgtaacattg gttatatcac tatcaagagc cataaccata
    43921 gatgtccttg cctcttcatt aggcaccata cctactttta tgttcttcat ggtctttgga
    43981 acttcttcat agtaatcttt gtttacagat aaaaccattc cttctctttc tgtatatgat
    44041 tctattttat atttcccatt tcctatcata ttattattct tgtcatttac atcctttgaa
    44101 tctaaatgat tttgagatac gattggaaaa attaaactat caattgaaaa agcatatcta
    44161 gctttaaatt ttattgtaaa atctttatct gatttaatat tcacagaagc tatattttta
    44221 gtaaattcat tatatggact atctgcactt ttttgaatta aaccaatagt atagtttaca
    44281 tcatttgaag taacattttt tccatcatgc cactttgcat cttttagctt tatatctata
    44341 ctcattccat cctgagctat attatactcc ttaactaatt gaggaattac attgtagttc
    44401 tcatctatag taaataaact atcataaact aaattcatta tataaccaac agacttatca
    44461 gtattagtta taggatttat agtttttgga gttaccattg ttaagtttat atacttagca
    44521 tctatagaac tttgactttg taaacttgaa tcactactac tttgttttgt tttagtatta
    44581 ctacaaccag ctaccataag agttatagct aaaacgactg ttaagacttt tattctcttc
    44641 attagttttt tcctttcttg ccatatatct tattataatg ttcgtaatta ttttttactt
    44701 tttctacata ttttgaagtt tgcttaaaag gtatatcatg tagattttcg ccatctttac
    44761 tatattcatt attttctaac cattttttca cattacctga accaccatta tatgcagcta
    44821 tcactaaatc taatttacca aattctttgt ataacttact taaataccaa cagccaagtc
    44881 ttatattagt ctctgggtcg aaaatatcca cattttttaa atttagttcc tctgctcccc
    44941 aatctctagt tatatctaat atttgcatta atccttttgc ttcctttttt gaaacagcag
    45001 aactattaaa cttactttcg gctttaataa cactgtaaac tatattttca tctaaattaa
    45061 attcttttga atacttttct acatactctg aatatttttt aggatataaa aatttatgta
    45121 ttactttgct ttccattaat agtgccccaa ataagattat aaaaatagat agaatcaata
    45181 ctttcttact attcacgcca attctccttc atgtactcaa taaatttatg tgctttactt
    45241 tctaattcag ttattgttcc cgaattatct attatataat caccatattt ggatttttct
    45301 tcctgactca tctgtgaatt tatcctacta agtgcttcct gcttactaca attatctctc
    45361 ttttgtattc tactaatttg tacttcttgt ttgcaagtaa ctactaatag cttgtcaacc
    45421 atatctaaaa aaccactttc taccaatatt gctgcatcta atactactat attttcgcct
    45481 ttttttctca attcttctat ttcacttatt attttttctc ttattcgcgg atgagtcaag
    45541 ctatttaatt ccttaagttt ttcttcatcg ctaaaaacta ttttcccaag agcttttcta
    45601 tttagagttc catcatcatt ttttatactt tgcccaaaat ggacaaatac tttttccaat
    45661 aacaacttat cctcaaatat cttcctggat ataatatcag catccactat agaaatatta
    45721 agatttctaa atatatttga taggctgctt tttccacagc ctattcctcc tgtaagtcct
    45781 aatatcaaca taaaatcacc tactttgtct cataccaaga actacctaca tttaaatcta
    45841 catctaagtg aacatccata tttacagcat tttccatttc ttcttttact attttcttaa
    45901 ctatatctat ttcatcatca attgcttcaa ctatcaactc gtcgtgaact tgtagtataa
    45961 gttttgattt caaattgttc tcttccaatt ttttatgaac atttatcata gcaattttta
    46021 ttatatctgc tgcacttcct tgtattggtg cattcattgc aaatctcttt cctctatttc
    46081 tttccataaa attgcttgac tttatttctg gtatatatct tcttctgttt aaaattgtta
    46141 cagcatatcc atcctcacta gccttttcta ctgttgtgtc cataaactct tttattttat
    46201 ggtatttagc aaaataactt tcgatatatt ctttcgcctt tggaacaggt atatttaaat
    46261 catcagctag accaaagtca cttttaccat atataatacc aaagtttaca gctttagctg
    46321 cacctctcaa ttcactagta acatcttcca taggaacatt aaaaacttgt gaagctgttt
    46381 tggtatgaat atcttcatga tgtttaaatg cttctatcat attttcatcc tgactcatat
    46441 gtgcaagaac tcttagctct acttgtgagt aatcggcatc aaccaactta cagttatcat
    46501 ctgcaataaa cacttttctt atttttctac ccatttccat ttttataggt atattttgaa
    46561 gatttggttc tgtagatgaa attcttcctg tagtcgttat agtttgatta aatgatgaat
    46621 gtattctatt actttctgga tttattatat ttaaaagtcc ttcaacgtaa gtagaattta
    46681 actttactat ttgtctatac tcagttatct tatctattat tggatgctta tctcttaatt
    46741 tttctaaaac atctgcatta gttgaatatc cagttttagt ttttttaatt attggaagct
    46801 ctaatttttc aaataatata acacccaatt gttttggtga atttatattg aatggctctc
    46861 ctgataattc ataaatttcc ttttctagtg tagctattat ttctttaaac tctacactca
    46921 attcatccaa tatacttttg tctactttta taccttcata ctccatatga cctaagactt
    46981 ctactaaagg catctctaca tgataaaaaa gaccatccat actcatatcc attagacttc
    47041 tttccatcat aggaattgtt tctttaactg tgcatattat ttgacccata tactctgcta
    47101 aatcctcaaa ttctaaatcc tcatagtttt tagatttaac accctttcct aataattctt
    47161 cttttgattt aacctttttt gataaatact tcatagctat tgcactacaa tcatatgagg
    47221 tagatgaagt tgaatctatt aagtactcag ctattgttat atcaaaatac atattttcta
    47281 agtttatatt atatggtttt aaagatatat aatcatcttt taaattatat ccatactttt
    47341 taatttcatt atttgaaaat atactatcta actttgacac ttcatttgaa tctacataat
    47401 atattttttc tccatctaca cttataaaaa tatatattat atttttttca agtatattac
    47461 cttgtcctct aacagttttt aaaataactt gtcctttttt gtttacttca tctataaatt
    47521 tttctgtatc ttttaatttt aatatttcta ttttttcttc tacgtgttct gtgtcatctg
    47581 aatcgaccaa atcaactaat cttgataaga gacttgtaaa tccaaagtat ctaaatttat
    47641 ctaaaagttc atctttatca taatcgccaa aaaccatact atctaaatcc acttctattg
    47701 gcacatctct tataattgtt gcaagtcttt tactttgaat agctatttct ttattttcct
    47761 ctattttctt ttttacacta cctttaagct tatctgtatt ctctattaaa ttctctatac
    47821 tagaaaactc ttttataagc tttatacctg ttttttcacc gattccaggt actccaggta
    47881 tattatctga cttatctccc ataagacctt ttaaatcaat aaattgtgct ggagtcatct
    47941 cgtatttttc aattacagaa ttaaagttgt attcttcaac ttctccaact cctttttttg
    48001 ttataagagt agttgtatta tctgaagcaa gttgaatagc atctttgtct ccagttacta
    48061 tgtatacctt atacccatta ttttctgctt ttttagaaac agttcctata atgtcgtctg
    48121 cctcataccc atctatttcc aatctattta ttttgaattt atctaaaagg tcttttaatg
    48181 gctgtaattg ttctgccagt tcatctggca ttccctttct tccagcctta tactctttat
    48241 attctaaatg tctaaatgta ggtgcttttc tgtcaaaggc tacacttata tgtgttggtt
    48301 tatatatatc tatcatttta aatagcattg ttgtaaatcc atatattgca ttggtcttta
    48361 acccttcttt attattcatt tctggcagag cataaaaggc tctgtttatt attgaatttc
    48421 catctattat aattaatttt ttttccaaat tatatcactc ctaaaaatta tctatttttg
    48481 taacatatat attatatacc aatatagtgt tatttaatat tcccataata ataatagtat
    48541 attaaaatta aatatgttgc aaacaatata tttttttgct ataataatat acatgacatg
    48601 cccgaatggt tgaattggta aatacaatgg attcaaaatc aactgtgttg attcataagt
    48661 ttttataatg ttttacagtt tgatgagtat tttgtattca atattcctct tgcatattct
    48721 tggaaaatct ggtaggatat acaagtagtt tggatttaaa atataagccg ctgtggcgga
    48781 actggcatac gcatacgact caaaatcgta cgggaaacca tatgggttcg agtcccatca
    48841 gcggcaccaa taaaaaaaac tctttagtat atactaaaga gtttttttat tgtaatattc
    48901 tttcatcttt atttctagcc ttgtataagt ataaatacca tagtcataac ttcttgaact
    48961 cctaaaatat atctaaacaa agtaggattt tttatgtatt cacttaataa atccatactt
    49021 cttatcatat tgattttttc ccaatctcta aaaattttga tacaaataaa aaatacagag
    49081 aactacttga tatactagaa ggttattctg taccatttgg tattgctgta ggtgttccag
    49141 atggaaattt accaaatgct agagatgtag tttataaagt ttctagagtt taggataaag
    49201 tgttgcaaca atcaattagt tacttgaaga gttaaatcag taatatacaa ataaattaat
    49261 ggaagaggaa gctatttaaa aagtagttta gatttttcat tgtaaaataa ttaaataaag
    49321 aataaggtga taagtatttt atttattatc ttattctttt ttatttgtgg aatgataaaa
    49381 ataagaatta agtgtaatac aatgtaaata aaatgtgtta attttaagta tattttgtaa
    49441 agtttataaa atctgaaaag ctcaagatat attttcacta taatggataa aatatcaaaa
    49501 tattgaaata aacaaaaaat aatgatataa taagaaaaaa taaagaaaaa aagtaaccct
    49561 tagttgtaaa agggttattt ttttgtgata aaatatccat aaaaatattc ataccaaagt
    49621 aaattaagat gtatttcatt tctcaaaaat atcctaatat aaaaaataaa gaaatattta
    49681 taaatttaat tattagacat agataatatc taaaaaatat accaatttca acaaatagta
    49741 acttttttac aacaaatgga aactatggaa gcaataatta aaataaaatt tataatcaat
    49801 cataattatt tagtataatg attcgatatt attttaaagt atttgtcatt taaaacaaac
    49861 ttgcgataaa agcatatctg aaagtattct gattctaata cttaataaag agttcttttt
    49921 acagttatag atataaacaa catctatctt aatagactgt atagaggcac aatcaaaggt
    49981 aaacacatat agttaagtaa tatgtccttg atttttcttt attataatag ctttattaat
    50041 tcattttaat attacatcat tttaaaaaaa ttatatgaaa agtcaaaatt tacatataga
    50101 ttaattaaac ttgtaaaaac acatataaat tcatacaatt aagtacttaa aacttgaaaa
    50161 tacttacttt gctatatatt ttagataaag atataattga tttggttaag aaaggagtct
    50221 aatatgatat tcagtagttt aatattttta tttttattct ttccagtcac actcatttgc
    50281 tattacttgg caaatcctaa gtataaaaat gttatgttac ttctagcaag tattgcattc
    50341 tacgcatggg gagaaccaaa atatattttt ttgatgatac tatcaataat agtaaactat
    50401 atatttggta ttaaagtttc tggcagtaaa aataaaaaaa tgtgggttgt gctttctgtt
    50461 atttacaata tatctattct tgctgtattt aagtatagca atttttttat agataatatt
    50521 aattttttat tcaatacaga tataactata cctgaggtta aattaccttt aggtatctca
    50581 tttttcacat tccaaataat gagctatgta atagatgtat atagaaatga tgctaaagtt
    50641 caaagaaaat tagctaattt agcattatac ataagtttat tccctcagct tgtagcaggt
    50701 cctattgtta gatatcagac tgttgcagat agcattgagt atagagaaca caattgggac
    50761 aaatttactc aaggtgtaaa cagatttgtt gttggtcttg gaaaaaaagt aattctagca
    50821 aatcaattag gtgtaatcgc agatggtgta tttaataagt cagctggaga tttatcaaga
    50881 cttgaggtat ggctaggtat agtttgctat acacttcaaa tattctatga ctttagtggc
    50941 tatagtgata tggccattgg tttaggtaag atgtttggat ttgagttttt agaaaatttc
    51001 aactatccat atatctctca aacagtatct gagttttgga gaagatggca tatatcttta
    51061 ggtacttggt ttaaagacta tgtgtacttc ccattaggtg gaagtagagt ctctaaggca
    51121 aaactatata gaaatctatt tgtagtatgg tttttaaccg ggatgtggca tggagctagt
    51181 tggactttta ttatatgggg tctatattat ggaatattaa tatcagtaga aaaagcattc
    51241 ttagaaaaat ttctatataa gatgccaaga attgtaagac acatatatct acttcttata
    51301 gtcatgattg gatgggtatt ttttagagtt gatgatttac cagcagctat taaatttata
    51361 ggtattatgt ttggtgctgg aaattatccg gttatcagtg atgcattcaa tgtatttata
    51421 attgaatatt ggtatataat tgttggggca atccttctat caactcctat tgtaaaagtt
    51481 gtaaaatcat tattaattaa gaaaaataaa aatacattaa atagcacatt atatcaagtt
    51541 actaatgtgg ttttcattgt ttcttgtatg tttattgtaa taataatgtt aagtagctca
    51601 acctataatc cattcttata ttttagattc taattgggag gtataaacat gagtaaaaaa
    51661 aaaccaagga ttgttgccat ttcattttta attatagtat ttggattttt catactaaac
    51721 ttcacacttc caaagaaaaa attaagtata actgaaaata gaaatcttgc aaaatttccg
    51781 actgtagaaa atttaaaaaa atgtgacttt atagccaagt ttgaagaata ttttaatgac
    51841 cattttgcat ttagagatga aatgatatca ataaatacaa ggactcaggc taatttaaat
    51901 aaaactaagg taggtaacta ttatctagga aaagataact ggatattagg tatgtttcca
    51961 gaaattttag accaaaaaca attaagtcga tacgaaaaat ccattaatta tttatctaat
    52021 ctaagtaaag atatgggaaa aaatgtgtat tttacaatga tgccacataa aactaatatg
    52081 ttaaaacatt tgtatcctaa atatgttgat aatatggata atatagacat aaatttaaag
    52141 aattttaaaa atagattaaa tccagattta attaaatata tagatatgga tgagtatttt
    52201 ttaagtaact attcagataa agaaagagaa aatttatatt ttaaaactga ccatcattgg
    52261 actggatatg gagcatttga aggctttaaa atgatggcat caaatatgga cttaggtcta
    52321 tctaagcaag atttagacaa gcattttagt agctataaaa agtctataat tactgataag
    52381 aaatttatag gaagttataa tcaaaatata gatatgctaa ttaaagaaaa tgaatatgta
    52441 gtttatatga caaaagataa ccaagattat agctttgata taaatggaga agaaaaagaa
    52501 gaaaaagaag aaaaagaagt ttatgcaact gaaagagata ataaagagtg ggattatggt
    52561 ggtgcataca ttagaggagc taaaactaat atattaacta taaaaaaccc taaagcatta
    52621 gtagataaaa aaatactaat atttagagat tcatatcagg ctcctacaac acttttattt
    52681 gctgatatgt ttaaagaagt agagatagca gaccctagaa atataaactc aatatataaa
    52741 acatacaaag agataatcga ggaaagtaat gcagatattg taatgtttat gtataatagt
    52801 tctgggtttg attcaatgat agattcaatg atagataaag gaataaagta gtaaataaaa
    52861 agcctctatt aaattcaaaa tttaatagag gctttttatt gtttattttt tattgctttg
    52921 gtaaaaataa actaatcaaa ataaaagtaa ggagatgtag catattgaac aaaagacata
    52981 gtctacctat agtatcagtg atattattga tggtcttaat tatctttaat aataaccaaa
    53041 attatattac aatgaaagaa gtttttaatg tccatattat gcagagtcaa aataaaaaga
    53101 ttaaacaaaa gtattatcta actaaagatg gatggctatt aggcaacttt gctaaattat
    53161 tatctgatta tcatataaaa tcttactcca aagccattaa taacttgagt aagttaaata
    53221 gaaaaaaaga tttttacttt gtttcacttc ctcataagac aaatatgctt aagcacttgt
    53281 atccaagtgg tatagaaggt aaaaataata tagatattaa caaagaaaac ttagaaaagc
    53341 agttaacaga cataaatttc ttagatatag atgattactt ttatagaagt tttaccgaaa
    53401 aagagagaga aaaattcttt ttaaaaacag accatcacgg aaattcatta ggagcatttg
    53461 aagaatataa gtttattctt gataaattag accttggctt atctaaatca gaaatagata
    53521 gtcatttaaa aagatacagt actcgatatg taaatgacaa ggtctttata ggtagttata
    53581 ataaaaagat gggatatcca cttaagaaaa aagagtctat aagctatgtt gaaataagtg
    53641 atgcaaatta caaatatttt attagtaatg gtactaaaaa tactgagatt aatgaaaata
    53701 tcataaaagc aaaattaaaa gataaaagag aatgggacta tggtggagct tatatgagag
    53761 gttgtgattg tcacatactt aagattagaa attcaagctc tttaactaat aaaaaggccc
    53821 ttatatttag agattcgtac caagcaccta tgacttggat gttggctgat acttttaagg
    53881 aactcgaaat actagatcct agatatataa aaaatataga tatgacctat gatgagataa
    53941 ttaaaaacag taatgcgaat gtagttttat ttatgtataa tagctttgga tttgctggaa
    54001 tgatacaaga aatgattgac aagggaatag cataacaatt tgaatcagct cctttttata
    54061 caaaaaatag ttctcaataa ttcctaatct atatgataat ttagtacatc tctttaacaa
    54121 taaaaataaa atcacaaaaa ttcttatacc atcacttatc tttatgataa attggttgag
    54181 aaaaaatttt ataatttata tgatatgcaa tcttaattaa ttctttatct actgcaacct
    54241 ttaataaaag aaaccatcca agactattaa tatgaattta tataaaaatt actttcaaat
    54301 aaagtactgc agtattttta tttaaagtat ctataatctt taaccacaaa aagccacaaa
    54361 atacaatgta tacttatggc tttttataaa tttatataat tgtatataaa gatatattct
    54421 aaaactgtct taagaatcta aagtttaaaa atccaatatt tttattgtga atttaaactt
    54481 tttattacaa ctttttatct aatttattgt atacaacaac actacaaata aattgaaata
    54541 aaataagcaa tccaagaaca actaaaaccc acttgcttat taccattaca gaaaatacac
    54601 tcaatataga aacaataaat ataagaatta caagaacata ggacatgatt tgattagtga
    54661 tacgtccagc tttatcacgt aacataactc ttctttcatc attcatctct atcctttggt
    54721 tttttatctt ttcttcataa tctactgctc tttcaggctt actccaatac atatattgaa
    54781 aaatcataca tatacctgga cctaaagcag ctccagataa tccccaaata aaagcctcaa
    54841 atgaaaactc agtaaacgta gccaataaaa caagtaaaat tccacaaata aaatatacta
    54901 ttccaagata taacatattc tttttcattt ttactcctcc tcataaataa atatttcttc
    54961 aatactcatc tgaacctccc atgactaaag tcacagggtt cctgcttcac agaattttgc
    55021 atactaaaat atgtcttact aattctccac aggccatccc cgtagttcct acggttctta
    55081 catacgttat ttattttgaa ttgttattaa tcttaatcct tcttttaata tatttatact
    55141 tgcatttata tctctatcat gagtttcatt acaactagga caaatccatt ctcttatatt
    55201 taagtcctta acttcctcgt ttttataccc acatttattg catatttgtg aacttgcaaa
    55261 gaatttgcct acttttacaa tttgtctacc ataccaatta gccttgtatt ttaattgatg
    55321 aataaattct gaccatgata catcagaaat t
//
LOCUS       DAMJWO010000013        54506 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.014, whole genome shotgun sequence.
ACCESSION   DAMJWO010000013 DAMJWO010000000
VERSION     DAMJWO010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54506
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.014"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(355..3462)
                     /locus_tag="PC366_000868"
     CDS             complement(355..3462)
                     /locus_tag="PC366_000868"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HDF2576407.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEVYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAEKAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGSKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVIKK"
     misc_binding    complement(3555..3787)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(3962..4489)
                     /locus_tag="PC366_000869"
     CDS             complement(3962..4489)
                     /locus_tag="PC366_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HDF2576408.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCRENTA
                     LKEKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(4524..5309)
                     /locus_tag="PC366_000870"
     CDS             complement(4524..5309)
                     /locus_tag="PC366_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HDF2576409.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYEQAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITKKGKIKVQARLIV"
     gene            complement(5319..5576)
                     /locus_tag="PC366_000871"
     CDS             complement(5319..5576)
                     /locus_tag="PC366_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HDF2576410.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFNILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(5595..6053)
                     /locus_tag="PC366_000872"
     CDS             complement(5595..6053)
                     /locus_tag="PC366_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HDF2576411.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     AKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(6093..6797)
                     /locus_tag="PC366_000873"
     CDS             complement(6093..6797)
                     /locus_tag="PC366_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HDF2576412.1"
                     /translation="MGSIKDNLSEIRNKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGDKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYNKK"
     gene            complement(6807..7442)
                     /locus_tag="PC366_000874"
     CDS             complement(6807..7442)
                     /locus_tag="PC366_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576413.1"
                     /translation="MKKVKYTRLVILGILIYLVFNILVMIISKNVDTLVLKNEKVDAK
                     IPVKGTIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYHEQKLDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVIDEQSQSV
                     KFVILEGITYENESSVFVDYYKNDINGVTSVNLYDKIILRPNSINTNIRIK"
     gene            7823..8863
                     /locus_tag="PC366_000875"
     CDS             7823..8863
                     /locus_tag="PC366_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2576414.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGIITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
     gene            complement(9326..10681)
                     /locus_tag="PC366_000876"
     CDS             complement(9326..10681)
                     /locus_tag="PC366_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009170073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HDF2576415.1"
                     /translation="MNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREKI
                     YNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDENDYVKFAQTLDKA
                     AEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMDA
                     VKEMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGVS
                     GPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLDVPFGIIDLSLA
                     PTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIPV
                     SEDAGMIDAVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGMI
                     NNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPISTNSSELFTQRGGRIPAPIHSFK
                     N"
     gene            complement(10707..10976)
                     /locus_tag="PC366_000877"
     CDS             complement(10707..10976)
                     /locus_tag="PC366_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDF2576416.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
     gene            complement(11266..13206)
                     /locus_tag="PC366_000878"
     CDS             complement(11266..13206)
                     /locus_tag="PC366_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576417.1"
                     /translation="MKKYEIFIFMSIIVLCFISFPHKVFGQEENCLEDFERWVQENKN
                     NKEEIVYTLSCNMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHIENGGSISIGINNIIATDGTALYVEEGGDLHIKSSYESVEKIKANGKDAI
                     GIYTENDIRILNKDIEVNGEHAIGVYSKGDVEIEETSIKAYSSNNESGLLRDNNKLAQ
                     SIISESKKVYIIDDYNELIPSIAKDSGYNIVKCCHRGIGVFSDEIKVSKDDKIENIKF
                     PKYMVLETSSGNQLDIDVEWDFTDYYEKLEKGENFDITGKFKTEMLNKEKIIINDDVV
                     PILNVSVIEKKTIDNLELEFQNTKNGYVAVLFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRVKVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEREND
                     DIDGDRGGGGRDDPDRDEDDNNQDGNNGNENNDSNNNQNNNNENNNSDEKQPNTPKDD
                     VESSTDSNENKNPHDIPKDGNKENNSDKEKGFYNKNPITENDDNYDLSSKSVFGTNEH
                     SFPYRESISNKNQDTNKNKSNISDYDGIINNNYKLESKEYNLKKDIIFLFCILTPIMI
                     GSILIVNPDTRKSIIKFIKLKK"
     gene            complement(13390..14865)
                     /gene="spoIVA"
                     /locus_tag="PC366_000879"
     CDS             complement(13390..14865)
                     /gene="spoIVA"
                     /locus_tag="PC366_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HDF2576418.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIIQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(15037..16332)
                     /locus_tag="PC366_000880"
     CDS             complement(15037..16332)
                     /locus_tag="PC366_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2576419.1"
                     /translation="MSVEVNKPSIWKNFKVLIILFVAGAFIYALPYLKNYYYDTFAQA
                     FNLTNTQMGSLGSIYGLLAMVSYLFGGFLADRISARKLLSGSLIITGISGLVLTLYPP
                     YIVVFLIHALWGITTILTFWPALVKAVRMLASENEQGKAFGFMESGRGITNAIHLSLV
                     LILFGYISSKVSDKSGLTAIIVLYSAINVIVGVLVFFKLKDNEKEVSAKFDKEAFFAV
                     IKMPHTWIITIIMFCSYSANMSFYYFTPYSTEAFGATVVFASAISILAQYCRPVASAA
                     SGLLGDKVGSSKIISYGFILMIAGLLGVIFTPTKSSMIYILLIGCVAIYVSMYAIQGL
                     HYSLLEEGNYSLSISGTAIGIVATLGYLPEVLCPLAAGKILDAFPGVTGYRYYFIVLT
                     IVAIIGLVFTFIWMNMTKERRKELIEMNNKSNENTTKVS"
     gene            complement(16516..17925)
                     /locus_tag="PC366_000881"
     CDS             complement(16516..17925)
                     /locus_tag="PC366_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2576420.1"
                     /translation="MKKKIGFWDLVFMNISALFGIRWIAKSTASSFGLGLGSIPVWLL
                     FAFIFFVPASLICAELAATYPKDGGLGEWVKQAYGEKWGFMVSWLNWTSKIFWYSSFL
                     TFLAINIAYMLGNPDLSNNKMFILALSLIIFWLLSLVSTRGMAFGKFFTNTGALGSTI
                     PAILLIVMAFMSVVILKKAPSASIYTIQNIIPKIDANSLVSISAIIFALSGAETTANF
                     ITEMDNAKKNFPKAILTVAVLIGGIYILGSVAITMILPPDKIAASTGILDALAKVAQD
                     LGIGSWFIRIVAFGITLSVLGALILYIAGPVKMLFGNVREGVFPKQLTVTNKYNIPSN
                     AVIVQAIIVSLLLVGTNLLPSVDNIYNVLVTMTALTALFPYVLLFTSYIRLRKTRPNE
                     ERPYSIAKSDSVCINIARMVLVVTVVGILFSTAPVMETLKDNIIYEIEMIGGGLFVII
                     TGLMLWKNYEKKISNNSGR"
     gene            complement(17977..19116)
                     /locus_tag="PC366_000882"
     CDS             complement(17977..19116)
                     /locus_tag="PC366_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2576421.1"
                     /translation="MSNNMRLERLRKYMNEKSIEIALIFEPDNQFYISGFKAITYSRP
                     IVTVVTQDKIELIVPGLEELHAKEVAKVDNVYVYYEIPEMKEHGISHKHYLDIILNKY
                     PKGTTVGIEKDIVSASFSEYITDKSFAIKDVGSKIFEMRYVKDAKEIEFLKIAGYLSD
                     IGIKGSLENVRVGMSELEFDVAGDNALLKYVSENYPDTYIGFANWTCSGIDRTAQPHL
                     DSNTRILQRGDIVIHSRQVWYENYRAENERTFIIGKPTERQKEVFKIAVEAQQAGLDT
                     IKAGIPARMVDEAARAVVAKYGLELYSNHRIGHGLGLSEHEEPYLRFDNELILEEGMV
                     FSMEPGIYIPGVGGFRHSDTAIVGKNGATIITNYPRSVEELILDI"
     gene            19435..20085
                     /locus_tag="PC366_000883"
     CDS             19435..20085
                     /locus_tag="PC366_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2576422.1"
                     /translation="MTNKELQKKRILMYFIEAAQNIMENEGIENITLRKVADMAGYNS
                     STLYKYFKNLDHLISFASIKYFKDYNLNISRCIENVNDEYKKYIIMWKLFCKHSFDNA
                     QAFYQVFFNLSSDELSYITKQYYDMFPEDLGIHDSDISLMITGESIKERNKILLNNLV
                     DTGYIPAKDLDIINDIIISFYQNLLFLKKNTGKNSGDDELTMKMISSIEYIIKHAK"
     gene            complement(20242..21261)
                     /locus_tag="PC366_000884"
     CDS             complement(20242..21261)
                     /locus_tag="PC366_000884"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDF2576423.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIVLAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTGLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVAEKLDIDMPITNAIYSVINKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(21292..21906)
                     /gene="plsY"
                     /locus_tag="PC366_000885"
     CDS             complement(21292..21906)
                     /gene="plsY"
                     /locus_tag="PC366_000885"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HDF2576424.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(21941..23260)
                     /gene="der"
                     /locus_tag="PC366_000886"
     CDS             complement(21941..23260)
                     /gene="der"
                     /locus_tag="PC366_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HDF2576425.1"
                     /translation="MSRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRIFA
                     EVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAADK
                     EIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLDEI
                     VENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAIDTY
                     FEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTEQD
                     TKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAKTN
                     QRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTDIR
                     PPKITLFINDKDLTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(23294..24622)
                     /locus_tag="PC366_000887"
     CDS             complement(23294..24622)
                     /locus_tag="PC366_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HDF2576426.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEIGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLDVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADAHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNDKSASKTIEQIHQIQQKYLEKLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPENILKREKKVSIATG
                     HSAYEFIQSMADAMMDKFKNLQVNVYEIKNKFFGETITVSGLLTAKDLKEQLEDKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMRIKIIPCLNEGKDFVDKILK"
     gene            complement(24860..25060)
                     /locus_tag="PC366_000888"
     CDS             complement(24860..25060)
                     /locus_tag="PC366_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576427.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(25062..25994)
                     /locus_tag="PC366_000889"
     CDS             complement(25062..25994)
                     /locus_tag="PC366_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HDF2576428.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLLSQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLVLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNM
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(26039..26971)
                     /locus_tag="PC366_000890"
     CDS             complement(26039..26971)
                     /locus_tag="PC366_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HDF2576429.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYDLSFFHCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNDVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKSTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(27026..28315)
                     /locus_tag="PC366_000891"
     CDS             complement(27026..28315)
                     /locus_tag="PC366_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2576430.1"
                     /translation="MEDLNSIYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLRSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILQFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(28344..29036)
                     /locus_tag="PC366_000892"
     CDS             complement(28344..29036)
                     /locus_tag="PC366_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2576431.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(29051..29812)
                     /gene="pgeF"
                     /locus_tag="PC366_000893"
     CDS             complement(29051..29812)
                     /gene="pgeF"
                     /locus_tag="PC366_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HDF2576432.1"
                     /translation="MMKDYINIKNVQDIKEYVNLSGNCEELDEKLNSVNLVITCKNID
                     AKNREDMLKVCKECDLTFENITSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPL
                     LLFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIG
                     PSIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLRCSGVKKEN
                     IINLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(29809..30270)
                     /gene="nrdR"
                     /locus_tag="PC366_000894"
     CDS             complement(29809..30270)
                     /gene="nrdR"
                     /locus_tag="PC366_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HDF2576433.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIEEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(30292..30555)
                     /locus_tag="PC366_000895"
     CDS             complement(30292..30555)
                     /locus_tag="PC366_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HDF2576434.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(30659..31432)
                     /gene="sigG"
                     /locus_tag="PC366_000896"
     CDS             complement(30659..31432)
                     /gene="sigG"
                     /locus_tag="PC366_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HDF2576435.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(31524..32246)
                     /gene="sigE"
                     /locus_tag="PC366_000897"
     CDS             complement(31524..32246)
                     /gene="sigE"
                     /locus_tag="PC366_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HDF2576436.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(32271..33143)
                     /locus_tag="PC366_000898"
     CDS             complement(32271..33143)
                     /locus_tag="PC366_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HDF2576437.1"
                     /translation="MFKGFKGGYMVYIEYYVIENLVINYIIISCTSILTKRYNPKKNK
                     LLGASLGSAYSVAYLYPSMNILFTVPFKIIIMSIITLISFRSKSKKDYVHVALVFYLV
                     NIFISGSTYFIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTINI
                     NLLEKSFCCKALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQ
                     EIIGSLDDKTSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDR
                     EYGAIMNPNILPGF"
     gene            complement(33434..34708)
                     /locus_tag="PC366_000899"
     CDS             complement(33434..34708)
                     /locus_tag="PC366_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDF2576438.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGDIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEIPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(34992..36149)
                     /gene="ftsZ"
                     /locus_tag="PC366_000900"
     CDS             complement(34992..36149)
                     /gene="ftsZ"
                     /locus_tag="PC366_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HDF2576439.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLDTKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(36339..36692)
                     /locus_tag="PC366_000901"
     CDS             complement(36339..36692)
                     /locus_tag="PC366_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HDF2576440.1"
                     /translation="MLWVLGGLAFGVVVGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGVSLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(36791..37465)
                     /locus_tag="PC366_000902"
     CDS             complement(36791..37465)
                     /locus_tag="PC366_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF2576441.1"
                     /translation="MKKKIVILGAFILGIFISTYIKSLDPNRVYITLGQTESIESEVE
                     NTKKEIKNLKETLKNNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSTVTGPG
                     ITITMRDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VNLFAK"
     gene            complement(37470..38168)
                     /locus_tag="PC366_000903"
     CDS             complement(37470..38168)
                     /locus_tag="PC366_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF2576442.1"
                     /translation="MKKRFINKSIIIGSVVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKTEKENLQSEVNSVKKDIETYRGKNNKGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEINSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVFNTYMY
                     LKEDKLCMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(38191..38931)
                     /locus_tag="PC366_000904"
     CDS             complement(38191..38931)
                     /locus_tag="PC366_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HDF2576443.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNINLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSVDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
     gene            complement(39201..40427)
                     /gene="murG"
                     /locus_tag="PC366_000905"
     CDS             complement(39201..40427)
                     /gene="murG"
                     /locus_tag="PC366_000905"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDF2576444.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDIVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEDKL
                     VFTGNPVRKEILLSRKNIARKNLSISDEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMGSISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSTSKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            complement(40445..41575)
                     /gene="spoVE"
                     /locus_tag="PC366_000906"
     CDS             complement(40445..41575)
                     /gene="spoVE"
                     /locus_tag="PC366_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HDF2576445.1"
                     /translation="MPKENLKKQIDIRMKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIEKNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGAALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            complement(41627..42982)
                     /locus_tag="PC366_000907"
     CDS             complement(41627..42982)
                     /locus_tag="PC366_000907"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HDF2576446.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASIIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSNNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKANIFMNQTVEDFCV
                     LNYDDEVVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            complement(43001..43969)
                     /locus_tag="PC366_000908"
     CDS             complement(43001..43969)
                     /locus_tag="PC366_000908"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HDF2576447.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIITVVLAWISIIAVF"
     gene            complement(44010..45383)
                     /locus_tag="PC366_000909"
     CDS             complement(44010..45383)
                     /locus_tag="PC366_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HDF2576448.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREASAQNAFVA
                     IVGENLDGHTFMKPAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGDISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     TNTLIVNGDDKFLSTLKEKEHVYKLKTFGFNKNNDIYCESYTMEEDSLTFICVINGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            complement(45550..47529)
                     /locus_tag="PC366_000910"
     CDS             complement(45550..47529)
                     /locus_tag="PC366_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HDF2576449.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASQIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGVEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIESFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDAKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            complement(47541..47888)
                     /locus_tag="PC366_000911"
     CDS             complement(47541..47888)
                     /locus_tag="PC366_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576450.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGAKCILLIAIFSVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            complement(48374..49309)
                     /gene="rsmH"
                     /locus_tag="PC366_000912"
     CDS             complement(48374..49309)
                     /gene="rsmH"
                     /locus_tag="PC366_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HDF2576451.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAISTAKERLSEYESRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKPIETTGKLVDIIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNKGGRICIITFHSLEDRIVKNAFKHLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEIEVNPRSRSAKLRVAEKI"
     gene            complement(49339..50085)
                     /locus_tag="PC366_000913"
     CDS             complement(49339..50085)
                     /locus_tag="PC366_000913"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HDF2576452.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKEAKRVGIKDDD
                     VLNIAIIAIPVGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGIIAHVYLSKKNKHNISEE"
     gene            complement(50482..51768)
                     /locus_tag="PC366_000914"
     CDS             complement(50482..51768)
                     /locus_tag="PC366_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDF2576453.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPIGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDKLSKSIERFYPEEPESVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINENFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKEIILDYIEKSKKEGLSKEEFERTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LDYLDVIKDITFEEVEERLKEHFKEEYCVISIVEPK"
     gene            complement(51783..53048)
                     /locus_tag="PC366_000915"
     CDS             complement(51783..53048)
                     /locus_tag="PC366_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDF2576454.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSAKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSVSEFGYEDEIDSITSRELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIINIPRADFIKNVDEVKVIDEQMEITQGKLVMGYRANVDYADIDKYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSIMFISSGIETKDYDKAVEL
                     IKKQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFVFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            53364..54461
                     /gene="ychF"
                     /locus_tag="PC366_000916"
     CDS             53364..54461
                     /gene="ychF"
                     /locus_tag="PC366_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HDF2576455.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
BASE COUNT        16900 a         9980 c         5784 g        21842 t
ORIGIN      
        1 tcacgagtgt gcgtagctat tttttaatca atacttaact ttttgttttc accatacatc
       61 aaaacgcacc cctttgcata ataaataaac caccctgcag aacacacgat aaatttataa
      121 ataaatttat cagaagtagc ttactaaaaa tattattcat cctcacttaa acgtttattc
      181 attaatattc tatcacatga cataaataat ttatatgatt tatatagatt tatttattgt
      241 aaattttgga atattaaaac attttattga atagataatt atattacata aaaaatccct
      301 atagaaatct ataaactaat ttctataggg attttggtta actaactatt ctttttattt
      361 ttttataact tttatacctg tcatatggtc atttaagttt tgttcctcta aagatttatc
      421 atctactctg tttatttcta aagctaaagt ttcagacttg atatattcat taaaatggtc
      481 aacagcctta gcaatttcat catcaccaca gtattctatt actatattat ctaatacttc
      541 aaagttatta gattttctta attgctgtac tttagatata aattctctag cataaccttc
      601 attaatcaac tcttcagtta gcttagtatc tagtataaca aaaagattgt tttcaacaga
      661 tacattaaat ccttccttag cagttatacc tattaatact aaatccttat taaattcaaa
      721 agcttcgcca tctaaatcaa ctgttaaagt ctcacctttt tcaagtttat tagcagtttc
      781 atgagcattt aatttactta atgctccaac gaataaattc atcttagaac ctaataatgg
      841 ccctgcttcc ttaaagtttg gttttaaact aaagttcata tactcatcta aatccttagc
      901 aaatattacc tctttaacat taagctcttc ttttattaaa tcaactacat cacttattgt
      961 atcttcaaac ttaccatcta ctaacacttt ttgtaatggt tgacgaactt ttattctttc
     1021 tacttctctt gaagctctac ctaaagtaac taagttttta gctaaatcca ttttttcttc
     1081 taatttagta tctactaact cttcattaca tttaggatat tcagctaaat gaacagatac
     1141 ttctcctgtt aagtttctat acatttcttc tgacatatat ggtgcaaatg gagctatagc
     1201 tctacaaaga ccatgtaaca attcataagt tgtattgtac actgcttttt tatcttctgt
     1261 taattcagtt gcccagaatc ttcttcttga acgtcttata taccagttag ataaatcatc
     1321 atttataaaa tcttgtatca tccttaaagt tttatttaac tcaaatatag ctaaattttc
     1381 ttctacatct ttcattaaat tattgaactt agataatatc catctatcaa gttctggtct
     1441 atctttatat tctacaaaaa attcagttgg atttatatca tctgtgtttg catataaagt
     1501 aaagaagtta tatacattct tcatagtacc tataaattta ctttggattt cttttaatcc
     1561 atccatatca aatttagttg gagtccatgg tggagaaaca tatagtaaat accatcttaa
     1621 tgcatctgct ccatattggt caaacaattc cattggattt actgtatttc ctcttgattt
     1681 actcattttc ttaccatctt tatcaagtac aaggtctgga actaaaacac tcttatatgg
     1741 tgcttttcct aatacaaatg ttgatactgc aagtaatgag tagaaccaac ctctagtctg
     1801 gtctatacct tctgatatat agtcagctgg gaacaattgg tcaaaatttt ccttattttc
     1861 aaatggatag tggtgttgag caaatggcat agccccacta tcaaaccaac agtctataac
     1921 ctctgttact cttgtcattg gttttccaca tttttcacat tttaagtgta tatcatctac
     1981 atatggtcta tgaagttcaa ctgtttctgg atttacatct tctatagctt tttcagctaa
     2041 ttcagctctt gaaccaactg aatctgtatg accacattca catctccata taggaagtgg
     2101 agttccccaa tatctagttc ttgatattgc ccagtcattt agattttcta accagtttcc
     2161 aaatctcttc tctcctacaa aacttgggaa ccattttaca ccattattat tttctattaa
     2221 tttatcttta agtttagtca tctctatata ccagcttggt tttgcatagt atactaatgg
     2281 agtttgacat ctccagcagt gtgggtaatt atgaactact ttttctttgc tatataattt
     2341 attttcagaa gctagccatt ttattatttc aacatctagc ccatcttcca ttacaaatct
     2401 accttcccaa ggagtagatg taaatttacc agtttcatct actggttgaa taactggtaa
     2461 atcatatctt ttacctgtgt tgtagtcatc ttcaccaaat gctggtgctg tatgaactat
     2521 accagttcca tcttcagtag ttacataatc tcctactgta ataaaaaatg cttttttgtc
     2581 aacttctaca aaaggcatta attgttcata ttctaaacct tctaggtctt tacctttcat
     2641 ttcttctaaa acttcataat cttcacctag tactttatca gctaaaggtt tagatacata
     2701 atatacctca tcaccttttt taacttttaa ataatctaca tcagcattta ctgttaatga
     2761 aacatttgat ggtaaagtcc atggagttgt tgtccatgct aagaagtatt catcagcatc
     2821 ttttttctta aatttagcta taactgtatt agtttttact tctttatatc cttgtgcaac
     2881 ctcatgacta gcaagaccag ttccacatct tgggcaataa ggaagtattt tatgcccttc
     2941 atatatatat ccttctttgt tgaatttgtt tagtatccac catacagact ctatatagtt
     3001 attatctaaa gttatatatg gattatctaa atcaacttca taagccattc tctcagtcat
     3061 tattctccat tgtttttcaa atgagaaaac tgactctcta catttttggt taaattcagc
     3121 tattccatat tcttctattt gttgcttgct agtaagacct aactctttct ctacttgtat
     3181 ttcaactggt aatccatgtg tatcccaacc agcttttctc tttacttgat aaccagacat
     3241 tgttttatat ctacaaactg aatctttaag cgttctagat aaaacatggt gtactccagg
     3301 atttccatta gctgttggag gtccttcata gaatacgaaa cttgggtcat ctttcccttt
     3361 ttctaaagtt ttttcaagta tatttatgtc tttccaataa tcaaaaactt gtgcttctgc
     3421 ttgttttaca gaactgtcta ccaatggctt aaatttcgcc atgtaaatca ccctttccta
     3481 ctaaatatta taattccaaa attttttatt ctttcacata aatttaaata ctaaaaaact
     3541 cgcccccttt aaaccaaagg gacgagttat aaatcgcgtt accaccctaa ttctatatgt
     3601 aaactaaata ctagctacat ataacactct aatagtataa cggtactaac cggcacagct
     3661 tagtagaatt taatcgttca gcctgcagct caagagtgat ttttatcttt ataaattcat
     3721 tggttctcag catacccaat tctctgtaaa attatctaaa gataaatgtc tctatcaacg
     3781 cttttaaaaa tttatctgtg tttatatgaa attttataac aaataatttg aatagtcaat
     3841 atatttttga aaaatataat aatttctatt tttcttacat ttttatccta tttttaatct
     3901 ttgttataga tttctcaaac tcacacagtt attctacata aaaaataaac aaattacaag
     3961 cttattctaa agttgtagca gcttcatcat tactataatt atacactgtt gttccttcaa
     4021 atgcatttac acatttttca tctacatcat aaaaaatctc atcaacactt cttatttcat
     4081 cttctaacag tgatttaaat ttatttctaa atatcttaaa ttctttgact aaagcatcat
     4141 actcttttct tatctctatg acacggttat tagcttgttc tataatttgt ctagctttta
     4201 aatcagcttc ttcaacaatt atcttagcct ttttattagc cgcgctacaa gtgtcttctg
     4261 ctgcactttg agcagttatt aaagtagctt ttagtgtttc ttcaatattt tcatacttgt
     4321 ttacttggtc ttgatataac cctaattttt ctttaagagc tgtattttcc ctacatagag
     4381 attcataatc ttccttgatg atatctaaaa attcatcaac ctcttcatct ctataccctc
     4441 ttaaaccttt tttaaactct ttattttcta tctcaattgg agttagcatt acatttcctc
     4501 ccagctataa tttaaattag tccttataca attaatcttg cttgaacttt tatttttcct
     4561 tttttggtaa tatctcctat ttgtgttacc ttagctcttc ctttgcctct aatagaaatc
     4621 aaatcatcat tttttactat tttagaagtt gaagttatct tttcataatt gacatggact
     4681 ttttctccat ttatgtattt tgcactatct tgtctagata tattgtaaat accacttatc
     4741 acacaatcta acctatctga agatactgta aatgatactt ctttatattt tgaagaacta
     4801 ttaacaatat tttctctgga aatttccttt acaattacat tatttcttga aaccttttct
     4861 aagtttacaa ttataaaatc gcaaatatca ctacttacaa ctacttgaca aaagctatca
     4921 tgtataatta tatctccaat tttttctctt tttataccta gacccagtat tgaccctaag
     4981 taatctttat gagatatatt tttaaacttg aaattccctt ctatttgtaa aaatctaaga
     5041 gtatcttcta tatcttcata ttccatgtaa aatggataaa taaatacagt gcttctttca
     5101 gcttgttcat aacctccatc cacactgtat tttatttcat ttgtagaatt taatattgct
     5161 acagcatttt tcacttcata tggattaaga aactccgtag acttaacatc atagtttttt
     5221 atacaactat tagccttgtc tatcacttta aacattttat ttttcaagtc tatatccttt
     5281 atgtgatttg ttagttttaa tttatccatc ctatcacctt agaatataac caatactaat
     5341 tgtcttagga acatcaataa tactattgca attaaaggag aaaaatctat aggtccattt
     5401 gtatatttat acattataga ccttattggc ccttctattg gctctgtaag attttccaaa
     5461 atattaaaaa ttttactttg tcttccattt ggaaaccaag tcatcaagct ttttataact
     5521 atcatccatg ctattatatc taaaagataa taaagtgcaa ttcttattgt tcccatatat
     5581 taaccgcctt tttactattt attttgccaa gggaagaatg ctttactttc taattctttt
     5641 ttcatatttg catctatatc cacattatta ggagctagta taaatattga tttagaaacc
     5701 ttttgtatac ttccatctaa tacataaact gccccattca taaagttaaa tatagattta
     5761 cgaacttcag aattagtcaa tccttccaaa ttcactataa ctgcccttct ttgttttaga
     5821 tggtctgcta tagttgcagc ttcatcataa accttaggtt caactattac aactttcatt
     5881 tggctagttg tatgtaaatt tacaatttta tttgcttttg cagtactaaa gccactgttc
     5941 atttcttctt cttgaactat atcgtccatg ccactttcat attcatcttc aatataatct
     6001 tcttcttcat caactatcca attcttaaat ttagatatta ttccatttga cattattaac
     6061 ttcctcctta aaatttattc aaatttgagt aattattttt tattgtagtt tctttctcca
     6121 aagattgatg ttccaactct aacaatggta gccccttcct ctatagcaat ttcataatcg
     6181 tgactcattc ccattgacaa aacatccatc cctacattag ggatgtttag ttcttttatt
     6241 tgttttgata aatctttaag acctttaaat acacctctta tctcatcttc atcttctata
     6301 aaaggtgcca ttgtcattag accctttatt tttatatttt tatatttttc tgacacttct
     6361 ttgacaaaat ctacaacttc ttctctatca agtccatgct tagactcttc tttagatata
     6421 ttcacttgta ctaagcaatc tatttctctg tttatttgtt ctgcacgttt ttgaatttct
     6481 tcgcataatg caattctatc taaagagtgt atcatacaaa ctttatcgat tatgtactta
     6541 actttattgg tttgcaaagt tcctatcagg tgccagttta atttgtcacc tataatatca
     6601 tactttctag ctaattcttg gggtttattt tcaccaacag aagtgattcc ttccctcatt
     6661 gcctcattaa ctaagtctac atcaacagtc tttgtgactg ccaaaagggt aatctctttg
     6721 ctgtctctat ctactttttt tgcagcttta tcaattttgt ttcttatctc agacaaatta
     6781 tctttaatag aacccattat tatcacctac tttatcctta tatttgtgtt tatactgtta
     6841 ggtcttaaaa ttattttgtc atatagatta acacttgtaa ctccatttat gtcattttta
     6901 taataatcca caaatacaga agattcattc tcataagtta ttccttctaa tatgacaaat
     6961 tttacacttt gtgattgttc atcaattaca tatacaccac gtttattgtc ttttgttttt
     7021 atagaagttt taggtatttt taaacattcc atctgattat atattatatc aaattcttcg
     7081 acacttgtat cctgatttgc aacaatttgg ttacttattt ttaattttac cattatttta
     7141 ttattatttt catatatttt gtaaactttt gcatctaatt tttgctcatg atattcaatt
     7201 attacatttt gatttttttc aaagttatta gaatcttctt tactgatgta tgtagataga
     7261 taattacttt ggtcattggc atctttttct atagttcctt ttacaggaat ctttgcatca
     7321 actttttcat tttttaacac caacgtatct acatttttgc taattatcat tactaatata
     7381 ttaaatacta aatatataag aataccaagt atcactaatc tggtatattt tacctttttc
     7441 aaagactctc cccctataaa attactttca ttataagtac ttcttctaaa aaatgtttat
     7501 tcctttttta taagctaata ttttacgttc taataattat tttttccata ttaaatttat
     7561 tttttatcaa tcttcctata caagactgca ttatttatat ataattgtat tataaagtat
     7621 aagtttaatt tacattttat acattaagct tactttatat gtttttatag ttatttttat
     7681 ttttagatgc aatataaaac caattaagat ttaaaataac ttttgttatg ttgacattta
     7741 tttaggtaat catttacgaa tcgggataac gttatcataa caaaagttta tgtcctaaaa
     7801 aaaatacaag gaggattttc ttatgtcaga aattttatta ggaacaggtt tacttttatt
     7861 ggttctatgt tgtttcacaa tttttagtta caaggcccca tatggtatga aggctatggg
     7921 agctctagca aacgctgcat gtgctacttt cttagtagag gcattcaacc tttctttact
     7981 tggtgatgtt ttaggtatgg aattttttag aagtgttgga gctgctaatg gtagtcttgg
     8041 tggagttgct gctgctatac ttgtgccttt agccttaggt gtatctccag tttatgcagt
     8101 tttaatagga ttatcttgtt tagatttttc tatattatct ggattcgttg ctggatactt
     8161 tgtttctttc ttaattaagt ttatagagaa aaaagtgcca cctggagtgg atttagtggt
     8221 tgtaattctt ctatgtgcac cgctatctcg tcttatagca tcaaatgtag acccattagt
     8281 taatagtaca ctactacaaa ttggacaagt tttgatagaa gctaccaaca ttagccctat
     8341 aataatggga attatactag gaggcataat aacagtagtt ggaacgtctc cacttagttc
     8401 aatggctctt acatctataa ttggtcttac tggtcttcct atggcaatag gagcattagg
     8461 tgcttttggt tcagctttta tgaactcaac actatttgca aaattgaaat taggttctaa
     8521 aaaagatatt atatctgttg ctattgaacc attaacccaa tcagacataa tttcagctaa
     8581 tccaatacct atatattcta ctaatttctt tggaggagcc ttttctggta tcattgtagc
     8641 cttgatgggt cttgtaaaca tgacaccagg tacagctaca cctgtggctg gttttgctat
     8701 aatgtttgct tataatccag ttcaacaagt tcttataaca gctggtttat gtgctttatt
     8761 caatgtaatt gcaggatttt taggttcaaa aatattcagt acctttaaag ttcttactgc
     8821 tggtgaaata cgtggtactg atgtagaaga agaaattgct taaaaaacaa taagatttat
     8881 aaatttatat ctcaagtagt agagttttat attgtaggca attttattaa ttgcaaacgt
     8941 tttatttttt atttatgttt atgattatta tgtgtgttga atatttagat aaatttttat
     9001 ttattatttt tatttagatt tttgtttagt tttttatttg gttgatatat taggaataaa
     9061 aattagtata gtttattatt agttagatag cataactttt tagatacata aaaaatttta
     9121 tattaattag atattattaa aataaaagcg atacatgaat ttttaaatgt ccatgtatcg
     9181 ctttattttt gccataatct taacaactga tttttaaagt ttattatctt aacgaagttc
     9241 attatcttat ataatattta aatgcataga cttctttaat ttaaccatct aaatatttaa
     9301 ttaaatatta ttatatgtaa tataactaat ttttaaatga atgtatagga gctggaatcc
     9361 ttcctcctct ttgagtaaat aattcagatg aatttgtact tataggcatt actggtgctc
     9421 gtcctaaaag tcctccaaat tctaccatat cacctacatc acatcctggg gctggtataa
     9481 ttctaacggc tgtagtctta ttattaatca tacctattgc tgcctcatca gctatcatag
     9541 ctccaagcgt acctgctgta gtatttcctg gcacagctat catatcaaga cctacagaac
     9601 aaatagcagt cattgcttca agcttatcta tacttaaagc acctttaata acagcatcaa
     9661 tcatacctgc atcttcagat actggtataa acgctccact aagtcctcca acatgtgaac
     9721 atgccattac tccacctttt ttaacagcat catttaaaag tgctaatgct gctgtagtcc
     9781 catgagtacc aacaacttca agacccattt cctctaatat atttgctact gaatcaccaa
     9841 tagcaggtgt aggagctagt gataagtcta ttatcccaaa tggaacatcc aatctactag
     9901 aagcttcctt tgccacaagt tgtccaactc ttgtaatttt aaatgcagtc tttttaactg
     9961 tttctgaaac aacatcaaaa ggctctccct ttactttctc taaagctctc ttaacaacac
    10021 cagggccact tacaccaaca tttataattc tatcagcctc accaacacca tggaaagctc
    10081 ctgccataaa tggattatct tctactgcat tacaaaatac tactaatttt gcacaaccaa
    10141 aaccttttgc atcttttgtt aattctgcag tttcttttat gatttctccc atttctttca
    10201 ctgcatccat atttatacca catcttgtag aacctacatt tactgaagca catactttat
    10261 tagtacttgc tagagctttt ggaattgact taattagtat cttatcacct tttgtatatc
    10321 ccttttgaac taatgctgag aatccaccaa taaaatctat acctaaatcc tctgcagcct
    10381 tatccaatgt ctgtgcaaac tttacatagt cattttcatc tgttgcacct gcaataatgg
    10441 aaattggagt tactgatacc cttttattta caattgggat accaaattca cgctctatat
    10501 cttttccaac cttcaccaaa tctttagcag aactcataat cttattgtat attttttctc
    10561 tagctttatc tccatcaggg tctatacaat ctaataaaga aatccccata gttatagttc
    10621 ttatatccaa ctgttcttca tctatcatct ttattgtttc aagtatattt cctacattca
    10681 ctattatcac ctccccttac tgtctactac agattatgca ttgaattaaa tatttcttct
    10741 cgctgaattt ttacatccac tgataatttc ttacctcttt caaccaagtc ctcaaccgtt
    10801 ttctcaaaag aatttaatga tttctctaaa tcaactatca taatcatagt aaaataatcc
    10861 tgtaatattt tttgtgatat atctactatg ttgatatttt gcttgtataa ttcatcacta
    10921 attcctgcca ctatacctgg tttatccttt ccaattactg ttaaaattgc tttcataata
    10981 atatcctccc ttattttttt ataaatctta tatttttaca aattgaacta tgtattaaca
    11041 tatatttcat ttatttgtta gtaaaccact ttttatgtat atatttaata tattttaata
    11101 cctatacatt catttgtcaa ttttttttca atattccatt atttttatac tatttagaaa
    11161 attcatattt tatatatgtt ttctcaacaa taaatacagt tttcataata atgaaaggta
    11221 ttacttagca atctcgtgat tttctaaata atacctctct aaaaattatt tttttaattt
    11281 tatgaattta attatacttt ttctagtatc aggatttaca attaatatag aaccaatcat
    11341 aattggtgtt agtatacaaa ataaaaaaat aatatctttt tttagattat attctttaga
    11401 ttctaattta taattattat ttattattcc atcataatca cttatatttg acttattttt
    11461 atttgtatct tgatttttgt tagaaatact ttccctataa ggaaaagaat gttcattggt
    11521 accaaatact gattttgagc ttaaatcata attatcatca ttttctgtaa ttggattttt
    11581 attgtaaaat cctttttctt tatcagaatt attttcttta ttaccgtctt taggtatatc
    11641 atgaggattt ttattttcat tgctatcagt acttgattct acatcatctt taggagtatt
    11701 tggttgtttc tcatcagaat tattattttc attattattg ttttgattgt tattactatc
    11761 attattttca tttccattat tcccatcttg attgttatca tcctcatctc tatccgggtc
    11821 gtctctacct cctcctccac ggtcaccatc aatatcatca ttttcccgtt catcatctgg
    11881 cgtctcttgg ttgtctccgc ctcccattat aaatcctggt ttaaaaacta tatttgaata
    11941 cccttctttt aatcctccta ccacttttac tctaaaacaa cgcaacttaa aatcttcaaa
    12001 aaaaagtata gcttgatctc taatatcctc ctgttcttca gatatccaat tgattccatc
    12061 gcttgaatat tcaacaaaaa ccttacttgc actatacggc atatcataaa ataaaacagc
    12121 tacatatcca ttttttgtat tttgaaattc cagttccaaa ttgtctattg tttttttctc
    12181 tataacagat acattcaaaa taggaactac atcatcattt attataattt tttctttatt
    12241 taacatttct gttttaaact ttcctgttat atcaaaattt tctccctttt ccaacttttc
    12301 ataataatca gtaaaatccc attctacatc tatatcaagt tgattaccac tagatgtttc
    12361 taataccata tatttgggaa attttatatt ttctatttta tcatctttac ttacttttat
    12421 ttcatcacta aatacaccaa ttcccctatg acaacatttc acaatattat agccagaatc
    12481 tttagctata gagggtataa gctcattata atcatcaatt atataaactt tcttactttc
    12541 tgatataatt gattgtgcca acttattatt atctcttagt aacccacttt cattgttgct
    12601 actatatgct tttattgaag tttcttctat ctcaacatca cctttagaat aaacacctat
    12661 agcatgttct ccattcactt caatatcctt atttagtatt ctaatatcat tttcagtata
    12721 aattcctatt gcatcttttc catttgcctt tattttttca acagattcgt aggatgattt
    12781 aatatgtaag tctcctcctt cttcaacgta taaggctgtc ccatcagtag caattatgtt
    12841 gtttatacca atacttatac ttccaccatt ttctatatgt attactcctt cttttcctcc
    12901 ttcacctatt atattcaatt cattatcatc aataataaat ctcccatgat tttttatcaa
    12961 tattttatat ttgttggtat ctattgtaaa attactgtca taaggaatat aaaatctaaa
    13021 ctcttcatct attaccatat tacaagaaag agtataaact atttcttctt tattattttt
    13081 attttcttga acccaccttt caaaatcttc aagacaattt tcctcttgtc caaaaacttt
    13141 atgtggaaaa cttataaaac acaaaactat tatactcata aaaataaata tctcatactt
    13201 tttcatctta cactcctaga aattttttag ctttgaaaca atcctgtcga aacatatact
    13261 tcacccacta taatttttcc acaattatca attattgtca atttatataa gtatctttat
    13321 taattgttat aaataaaaag ctacttacta aagtaaacag acgtttcact ttaataagta
    13381 gctatatttt tataacaaaa tagttataat attagaactt ccttcattta caattttttg
    13441 taaagtcttt tgcattttaa ctcttatctc ttctggcata gtatataatt tactttgtaa
    13501 ttgctctttt actaagtcat gtagtgactt accaaacata tttgattccc ataaatctgc
    13561 tggttgctct tcaaatactt ccataagata ttttatcatc tcttcacctt gattttgatt
    13621 tccaactatt ggagagacct ctgtagatat atctgctttt ataatatgaa gtgatggtgc
    13681 attggctttt aacttgatac catattgttt tccttgtttc attatttctg gttcttccag
    13741 actaagttct tctaaagaag gagctactac tccatatcct tttatcttgg catctattaa
    13801 agcactttct attttatcat actcattttt aactttagat agtctagtta tcagactaag
    13861 cagttgataa tctccttcaa ttttaaatcc acttttttct tcaaggacat tatagaataa
    13921 atcttgcttt gtctgtaaat caatatttat aacaccttct cctagctcta cattatcaac
    13981 acctgtatct tccaaaaact ctaactcaga aaatccttgt ataatacctt ctatatctct
    14041 tattttacct atatctataa tactttgttt taatgttgtt attatgctac tttttatcca
    14101 atgatttctt tcaagacctt caacccattt tggtaagttg attcttattt ctgtaagtgg
    14161 aaaatcatat aatacagctt ccataacctc ctctatatct tcttcttcca tttcaaccac
    14221 attcattgga agaactggaa cttcatactt ttcttccaat tcacttctaa gcatactcgt
    14281 ttcctcactt tttggactta acgtatttaa aaccactgca aatggttttt taagattttt
    14341 caattcttgt ataactctct cttctggttc tacatagctt tttctgtcaa ttccagtaac
    14401 tgaaccatct gtcaagacaa ctatccctat tgtagaatgg tcttttataa cttttttagt
    14461 tcctatctct gctgcctttt caaatgtcat agcttcttgt gaccaaggag tggatactaa
    14521 tctttgtttt ccaccttcct catgccctaa agctccttca actatgtatc caacacaatc
    14581 taccattctt acttttaaag atactgtgtc ttttattttt atttctacac catctgctgg
    14641 tacaaatttt ggttctactg tcattatcgt tttacctgaa ccactttggg gtatctcatc
    14701 tcttgttcta tcctttttaa attcattgtc tatattaggt ataaccaact tttccataaa
    14761 ttttcttata aaagttgatt ttcctgttct tacaggtcca actactccaa tatatatatc
    14821 cccctgagtc cttttggata tatcttcgta tatgttatta ttcatattat tcctcctata
    14881 catctaatct tattaaatta tatttagagt taagggttaa tattcttaaa atagaaaaat
    14941 aaagaccagc aatattaatt taatttacat atagaaattt gtaaatttca atgtaaatta
    15001 aattaatatt gctggtccaa atagtagtgt attatattaa ctgactttag tagtattttc
    15061 atttgactta ttattcatct caataagttc tttacgtctt tcttttgtca tgttcatcca
    15121 tataaatgta aacaccaatc caattatggc tactatagta agaactatga agtagtacct
    15181 atatccagtt acacccggaa atgcatccaa tatcttccct gctgctaaag gacaaagtac
    15241 ttctggaaga tatcctaatg tagcaactat tcctatagca gttcctgata ttgataatga
    15301 ataattacct tcttcaagta acgaatagtg taaaccttga attgcataca tagatacata
    15361 tattgcaaca catccaatca atagtatata aatcatagat gattttgttg gtgtaaatat
    15421 tacacctaaa agacctgcaa tcataagtat aaatccataa gatataatct ttgatgaacc
    15481 tactttatct ccaagtaatc cagaagcagc tgatgctact ggtctacaat actgagctaa
    15541 tattgagatt gcagatgcaa acaccacagt agctccaaat gcttcagttg aataaggcgt
    15601 aaaataataa aatgacatat tagctgaata tgaacaaaac attattattg ttattatcca
    15661 tgtatgaggc atttttatta ctgcaaaaaa ggcttcttta tcaaattttg ctgatacctc
    15721 tttttcatta tcctttaatt tgaaaaatac taatactcca actattacat ttattgccga
    15781 gtataatact ataatagctg taagaccaga tttatcactt acttttgatg aaatataccc
    15841 aaatagtatc aatactagag atagatgaat tgcattggta attccacgac cactttccat
    15901 aaatccaaaa gcttttcctt gttcattttc agatgctaac attctaacag cttttacaag
    15961 agctggccaa aaagtaagta ttgttgttat tccccataag gcatggatta aaaacacaac
    16021 aatatatgga ggataaagtg ttaatacaag accagatatt cctgtaataa ttaaagaacc
    16081 tgaaagcaat tttctggctg aaatacggtc tgctaaaaaa ccaccaaaaa ggtatgatac
    16141 cattgcaagt agaccataaa tgcttcctaa gcttcccatt tgtgtatttg taagattaaa
    16201 tgcttgtgca aaagtatcat aataataatt ctttaaatat ggtaaagcat atataaatgc
    16261 tcctgctaca aagagtatta tcaagacttt gaaatttttc caaatgcttg gtttatttac
    16321 ttcaactgac atacttcctc cttatgtaaa tacctgtaaa ttttcatgat aattaattat
    16381 tgcttatttt attgtttatt caatatttcg gaatatttat taatatatta ggttaatcta
    16441 tcaataattt atggtgagtt atgagctaaa agtaaactct tttagctcac cataataatt
    16501 atatttttat ttatactaac gtccagagtt attagatatc tttttttcat agttcttcca
    16561 tagcattaaa cctgttatta taacaaaaag acctcctcct atcatttcaa tctcatagat
    16621 tatattatct tttaaagtct ccataactgg tgccgttgag aaaagtatgc caactacagt
    16681 tactacaagt accattctgg caatattgat acaaactgaa tcactttttg caattgaata
    16741 tggtctttct tcatttggtc ttgtctttct aagtctaata taagatgtaa aaagcaagac
    16801 atatggaaat aatgctgtta atgctgtcat agtaacaaga acattgtata tattatctac
    16861 tgatggtaat aagtttgttc ctacaagaag tagactcact attatagcct gaactattac
    16921 tgcatttgat ggtatattgt atttatttgt aacagtcaat tgcttaggaa atacaccttc
    16981 tcttacattt ccaaaaagca tctttactgg acctgctata taaagtatta atgctcctag
    17041 tactgataaa gttattccaa atgctactat tcttataaac caacttccta tacctaaatc
    17101 ttgtgcaact ttagctaatg catctagtat ccctgtagac gctgcaattt tatctggagg
    17161 aagtatcatt gttattgcta ctgaacctaa gatatagatt cctcctatta aaacagccac
    17221 agttaatata gctttaggaa agtttttctt agcattatcc atttcggtta tgaaattagc
    17281 agtcgtttca gctcctgata atgcaaatat tatagcagat atagaaacta atgaattggc
    17341 atctattttt ggtattatat tttggattgt atatatcgat gctgatggag cttttttgag
    17401 aataactaca gacataaatg ccatcactat aagtaatata gcaggaattg tagaacctaa
    17461 tgctcctgta ttcgtaaaaa attttccaaa tgccatccca cgagtactta ctaaggacaa
    17521 cagccaaaat attatgagtg aaagtgctaa aataaacatc ttattgtttg ataaatctgg
    17581 atttccaagc atatatgcaa tatttatagc taaaaatgtc aagaaagaag aataccaaaa
    17641 tatctttgat gtccaattta gccatgacac cataaatccc cacttctctc cataggcttg
    17701 tttaacccat tctccaagtc caccatcttt tggatatgtt gcagccaact ctgcacatat
    17761 aagtgatgca ggaacaaaga atataaaagc aaacaataac caaactggta tagaaccaag
    17821 acccaatcca aaactagagg cagtagattt agctatccat ctaatcccaa atagtgctga
    17881 tatattcata aatactaaat cccaaaatcc aattttcttt ttcactgtaa ttcctccaat
    17941 ttcaaattta ttcaaactca tacacaatgt attgatttaa atatcaagta taagttcttc
    18001 aacacttctt ggataattag ttataattgt agcaccattc ttacctacta ttgctgtatc
    18061 tgagtgtcta aatcctccaa ctccaggtat atatatccct ggctccatag aaaataccat
    18121 tccttcttct aatattaatt cattgtcaaa tcttaaatat ggctcttcat gttctgataa
    18181 acctaaacca tgaccaattc tatgatttga atataactct agaccatact ttgcaacaac
    18241 agctcttgct gcttcatcca ccattcttgc tggtatacca gcttttattg tatctaatcc
    18301 agcttgttga gcctctactg caatcttaaa cacttctttt tgtctttctg ttggtttacc
    18361 tataataaaa gttctttcat tttctgctct atagttttca taccaaacct gtctactatg
    18421 tattactata tctcctcttt gaagtatcct agtattggaa tctaaatgag gttgtgctgt
    18481 tctatcaatc cctgaacaag tccagtttgc aaatcctata tatgtatcag gataattttc
    18541 agaaacatat tttagtaaag cattatcccc cgcaacgtca aactccaatt cactcatccc
    18601 aactctaaca ttttctaaag acccttttat tcctatatca gataggtaac ctgctatctt
    18661 caaaaattct atttcttttg catcttttac atatctcatt tcaaatattt tacttccaac
    18721 atctttgata gcaaatgact tatcagttat atactctgaa aaacttgcag atactatatc
    18781 tttttctatt ccaacagttg ttcctttagg gtatttattt aaaattatat ctaagtaatg
    18841 tttatgtgat attccatgtt ctttcatttc tggtatttca taatacacat atacattatc
    18901 aacttttgca acttctttag catgtaattc ttctaatcca ggtactatta attctatttt
    18961 atcttgagtt actactgtta caattggtct agaataagtt attgctttaa atccactaat
    19021 ataaaattga ttgtctggtt caaatattaa agcaatttca atgctttttt cattcatgta
    19081 ctttctcaat ctttctagtc tcatattatt tgacataatg cacctctttc ttaatattca
    19141 gataatttat tcaatacaac aaggataaat atattatttt aaaattctta atatttttag
    19201 tacttgtcgt atttgcatgt aaattaattt tatttgtgat tattttatca taatcatgat
    19261 tattttgtca atcacgattt tatttttaaa atttttttat attctagtga ttttaaatta
    19321 tctaaaatat aacgagtata cattgtattt tggaatatta ttcttgattt atggtaagtt
    19381 taatgataaa atcacgatta tataaactat attgattatt tgtaggtgaa taaaatgaca
    19441 aataaagaat tacaaaagaa aaggatattg atgtatttca tagaagctgc tcaaaatatt
    19501 atggaaaacg aaggtataga aaatattaca cttcgtaagg ttgcagatat ggctggatat
    19561 aatagttcaa ctctatataa atactttaaa aatttagacc atttaatatc atttgcatct
    19621 ataaaatatt ttaaagatta taacttgaat atttcaagat gtatagaaaa tgtcaatgat
    19681 gaatataaga aatatataat tatgtggaaa ttattttgta agcattcttt tgacaatgct
    19741 caagcttttt atcaggtatt ttttaacttg tctagtgatg aacttagcta tataacaaaa
    19801 caatattatg atatgtttcc agaagattta ggtattcatg atagtgacat atctttaatg
    19861 attacaggag aaagtataaa ggaaagaaat aagatactat taaacaatct tgtagatact
    19921 ggatatatac cagctaaaga tttagacata atcaatgata taattatttc tttttatcaa
    19981 aatctattat tcttaaaaaa gaacacagga aaaaattctg gtgatgatga attaactatg
    20041 aaaatgattt cttctattga atacataata aaacatgcta aataaaatta aaatatggct
    20101 gtctcaaaat agagataagc cttttttatt gttgaaataa taaaaatata tttaatttca
    20161 tataaaaaaa agtgcctcgt aaactaaaaa gttcattttg agacacccct aaaacaaatt
    20221 tattatttat tatacaatag tttatatatc atcacctaaa actacttctt ccatttcatg
    20281 ctttttactt ctcatcatta gttctattcc aacttcttta ggatttgaac ctttatttat
    20341 tacagaatat atagcattag ttataggcat atctatatct aatttttcag caacatcatg
    20401 tgctacttca gtagcagtta tgccttctac aaccatcttt acttctttta aagtatcttc
    20461 taaactcata cctttaccta tgagtatacc agctcttcta tttctactat gcatacttgt
    20521 acaagtaact attaaatctc caatacctga aagacctgca aaggtagaca tattagctcc
    20581 catagcaatt ccaagtctgc tcatttcact aatacctctt gtcataaggg cagcttttgc
    20641 attatcacca taccctaatc cgtcacatat cccagctcca aatgctataa tattttttaa
    20701 tgctcctcca agttctactc caactatgtc tggattcgta taaactctaa gtttagggct
    20761 cataaataaa tcttgtatca tctgtgctat ttttaaatct ttagaagcaa ctactacggt
    20821 agtaggaata tcccttgcta cttcttcagc atgagatggc ccagatagta ttacatatgg
    20881 attttgtggt aattcttctt cacagacttg agataatcta agcccagtcc ctttttcaag
    20941 acctttagct acattaacaa taacttgtcc ttcttttata aatggtttta ttttttggca
    21001 agtacttctt acagcctgtg atggaactgc taaaactatt accttacaat cttttatagt
    21061 tttttctata tcagtactta tagttatatt gtttggaaat aatactcctg gtaaatagtc
    21121 tgtattttct ttagttctgt ttattttttt agcttgttcc tcttttcgag tccacatgct
    21181 cacatcatta cctttttttg caagccctaa agctaatgca cttccccagc ttccagtacc
    21241 taatacacat actttctcca tgtttaacac cacctgagta taatatattt actattcttt
    21301 cttttgacca atttttctct ctgtcccatt taataatcgc tttatatttg ctctgtgatt
    21361 atatattact gatgcagtta agaacagagc tactattaaa ccagctttat tttttaccat
    21421 aatcataaat attggtgaac atcctattcc tacaacagaa cccaatgaaa catactttgt
    21481 tatagctacc accaatataa atactgctag acacattagt gttattactg gatttacagc
    21541 tagcattgca cctagtgaag ttgcaacacc tttacctcct ctaaatccta aaactgctgg
    21601 ccaattatga cctgctacaa cacatataac tgccagatat ccagctaaaa gagtatctat
    21661 tccaaccaat cttgctgcaa attctgatat taaaacagcc attacacctt taagaacatc
    21721 acctaaaaat gtcattgctc ctgctctttt tccaagtgtc ctaagtacat ttgtcgaacc
    21781 tgcattacca gaaccttgag tccttatatc aaccccagca attcgctttg caactatgta
    21841 tgaggtagat atatttccta aaagatatgc aactacagca ataattatat aactaaatat
    21901 ctccactgaa tttcccccct ttagttatat tttaagatat ttatttttta tttttttgtc
    21961 tatactcaaa ctttatggaa gttccttcaa atccaaaatt ttctcttatc ttattctcaa
    22021 ggtatctttg atatgagaag tgagttaaat ccttatcatt tataaacaat gtaattttag
    22081 gaggtctaat gtcagtttga gtcccatagt aaatttttag tcttctacct ttgtcagatg
    22141 gtggttgatt taacattaca gcttctccaa ttacttcatt cagtgctgaa gttgatattc
    22201 tcttagaatg ttcatttgac acatattcaa ctgtatctag tatcttgttc attctttgat
    22261 tagtttttgc agaaacaaat acgattggag catacatcat aaatggaaat ttttctttta
    22321 tatcttttgt gtaattactc atagtcttat tatctttctc tattaaatcc catttattga
    22381 ttacaaatat gcatcctttt ccttcatcat gtgctatacc tgcaaccttt gtatcttgtt
    22441 ctgttacacc ttctaaggca tctattacta tcaatactac atctgctcta tctacagcac
    22501 tcatagctct tattacactg tatttttcta ttgtctcata tattttactt tttcttctaa
    22561 gccctgctgt atctattaga agaaatttct gtccattttt ttcaaaataa gtatcaattg
    22621 cgtctctagt agttcctgca attggactta caattactct ttcttctcca agtatcttat
    22681 tgagtataga actttttcct gcatttggtt tacctgttat agctactctt attatatctt
    22741 cttcatactc tgtatctaat cctgctggaa aattttcaac tatctcatct aataaatctc
    22801 caaatcccat actattggct cctgaaactg caaaaggcgt tccaaatccc aactcataaa
    22861 aatcatatat attatcaaat tgactttgac tatcaatctt attaaccact aagattactg
    22921 gtttttttgt ctttctaagc aattgtgcaa tttctttatc agcagctgtt attccagctt
    22981 taccatcaac tataaaaagt attacatgtg acatgtccat tgcaagcatg gcttgatttc
    23041 tcatttgaga taatattata tcttcgctat caggttcaat tcctcctgta tccactaatg
    23101 taaaatattt atctaaccac tctacttcag caaatattct atctcttgta actccaggtg
    23161 tattttcaac tattgatatc ctttttcctg caaatttatt aaatattgta gacttaccaa
    23221 cgtttggtct cccaactaca gctacaactg gcctacttat actcatttta tttctccttc
    23281 catcttttgt tttctatttt aaaattttat ccacaaagtc ttttccttca ttcaaacaag
    23341 ggataatttt tattctcata agttcttcta attgatttaa ttcaatatta tctaagaaaa
    23401 tttcttcatc tgcttttagc atacttcttg ttatataaag agcttctcct aattctttat
    23461 cttcaagttg ttcttttaaa tccttagctg ttaaaagacc tgatacagtt attgtctctc
    23521 caaaaaactt gtttttgatt tcatatacat ttacttgaag atttttaaac ttgtccatca
    23581 tagcatctgc catactctgt ataaattcat atgcagaatg accagtagct attgatactt
    23641 tcttctctct ttttagaata ttctcaggca atatatttag atactcttca atctctgttt
    23701 ttaacttacg tatcatacct acaccatctt caaactgtaa aaaaccttca tattcttcat
    23761 atccaggcaa ttcactatta gatagtatat aaaattcatc tgataaaaat gcaaatcgag
    23821 tacctaattt ttcaagatat ttctgttgta tttgatgtat ttgctctata gttttacttg
    23881 cgctcttatc attaaatata tttaattcta ctagattttc tctatgcttt gtaatcccaa
    23941 ctggaactat cgcaacactg tttacatatg gataaagttg agctagttct tttattgttc
    24001 tatccaattc ctttccatca tttatacctg gacataaaac aatttgacag ttcatttcta
    24061 tatgagcatc tgccaatctc ttcattatac catataattt tcctgcaaat ttattgctta
    24121 tcattttttg tcttaactct ggattagttg tatgcacaga tatatttata ggacttattc
    24181 tatattttat aatattattt atatcttctt cactcatatt tgtaagtgtg acaaaatttc
    24241 cttgtaaaaa agataatctc gaatcatcat ctttaaaata aagagtttct ctcatacctt
    24301 ctggcaattg gtctataaaa caaaacatac acttatttct acagctttta gcttggtcaa
    24361 ttatcggatt tgtaaattca acacccaaat cttcatcata gtctttttct atctcgtata
    24421 tgtagacttc gccatctttt ttttgtattt ctacatctaa atattcatca cttagtaaga
    24481 atctatactc tattatatca tgtattggct gttcattcac agatataagt aaatctccta
    24541 cctctatacc tatttcttct gcaatactat ctttataaac cttacttata atattattta
    24601 ctttttttac atttacttcc aatattttca ccactctttt gtattcatca atgcttatta
    24661 taatatattt taatatgcaa tttatttatt tattatattt tatgatagca tttttaagca
    24721 tttcatgtca taataacaca ttttaattct aatagtcaat ataagtaaat agctataaaa
    24781 tagattagaa caaataatat tcaaatttaa gtttcttaaa aatttgaata ttatttgttc
    24841 ttaaaaaaat tttataaatt taatgtttta ctatgattaa cgtcccattt gtcatatcat
    24901 gaaccattcc acctacacac tttgacatca acaatgcctt attttgtaag tctttctcat
    24961 catttgcata aaatattgga caacctccac catttttcat attcttatca agtgtaacta
    25021 tagctagggt atattcattt aaacctatat ccattcccat cttatgcact tcctttcttt
    25081 cctattttat aattttttag tgataagttt tttcctttag agcttgaaag tattgggcat
    25141 gactttacag cttccattac tttttccata ttcttatcta ctggtaaata agcaatcatt
    25201 atactttcat cctctttatt tcttctaggt aatggtacga atgaaggttc tccataatct
    25261 ccatataaac ctaaccttga atatatattg tatactattg cttgtctttg accggagtca
    25321 aataatattc ctgcattagc ataatcctta tttttaggaa ttatttgtat tcctacacct
    25381 ctattaatat atacttctct atcacttttt agacctatat ttgttatacc ttttaaatct
    25441 cccaccttta gtatagattc gtccacaaaa ctaatttcag caggcattac atcagctatg
    25501 tctccaatac tttttctagt aagaagtttt tttaatataa aggctaacac taatccacaa
    25561 attgaactta ttaccaaact catcccttca cttattttcg tttctgcaag tattacataa
    25621 tacaatccta ttgttaaaaa agatgtaact atacacatat aatttcttac ttcataggtt
    25681 ctagctatct cttctatgaa tgcagcacct ctctttacaa gttgaacttc ctctaaattt
    25741 tgcaatgtat ttcttctatt tgctctcact tgtctaaatt gttctgctgc tagagataaa
    25801 aatgttatgg atgtataaga acgatttata agagctggaa ccaataatgc tcctaatgaa
    25861 gaagcgacga atgctaatat aagttgagat agtaaaacat ttggttgcgt tggatactgt
    25921 ttttggtcta aattcaacat tataattcta gatgttatac caataataac agcaacaaaa
    25981 aatactctat ccattaaatc actcctaaaa tatttaattt gaaattttac atgtaaatct
    26041 acaaagtctt tctagaaaaa tcactctgct ttccttttga tgtttctatg ataggtgtac
    26101 ttttcactac atctatcatg acatctatat ctttgagtat tggcatatat ggtataacca
    26161 cagtactttt ttctaaattg gtcttagata tagcaacaat atcaacctca tctacatctc
    26221 tatctatccc catatgaata aatagattat gtattatagc ttgtctttgc cctatatcat
    26281 ttactattcc aaatgcacct aaatctcttg gtataacttc tatggccaga cattcatttc
    26341 tatacttttc tcttgtactt tctagaccta tattagttat tattacatca tttaccatta
    26401 aaataggtcc ttcaaaactt atttttgcag gaactatatc tgctatatct gctatactgt
    26461 ttcttcttaa aaatcttcta aaaatcaagc caacaatagc tcctgacaca atagctaaaa
    26521 ttgtgcaatg aaaaaagcta aggtcatact ttcttgcaaa aacgatataa actatcgaag
    26581 atactagtgc agaaaaaaga cttatataac ttctagattc atacgtagat gctatttctt
    26641 caacataagc atctcctttt ggtactaatt cttcattatc aatattcttt agtgttattc
    26701 tttcttgttc cgcaagacct tgaaactgtt gtattgctac tgcaaaaaat gtcaaggctg
    26761 caaactcctt atctataagt gcaggtaatg ctatagcacc taacgaagct gaaagcccag
    26821 atataattat ctgttctaaa taatcttgtg gtcttgatgg gtattgtttg tctgtaactc
    26881 ttaaaactaa tcctctacat aatattccta caactaatgc aactataaaa gagtgtctaa
    26941 ataaatttgc attcaataaa ctttcttcca ttttctcagc tccttctctt atatagtttg
    27001 tgcaaaaaac aaaaaaaatt cccttctatt taaggaaatt tttttgtaat attgtaacta
    27061 taaattcgct accaatgcca agttcacttt ttacttttat acatccattt agtgatttga
    27121 ctatatgctt tgttatagcc aatcctaaac ccgttcctcc tacatcccta cttcttgctt
    27181 tatctaccct ataaaatcgt tcaaatattc gttctacatc ttcttttggt atccctacac
    27241 cattgtctat aactttaatt acgatttttt cttcatcttt taacactaca acttgtacaa
    27301 tcccattatc ttgggtatac tttatagcat tatcaactag gtttaagaac acttgcttta
    27361 tatagtcttt attggatagt atacttattg atttatcatc acatttatat aaaacttcta
    27421 tatttttttc actagctgaa tgttgagtta tttcatatac ctctttaaat acatcatata
    27481 ctacaacatt ttccataaga agagtatctt tattttctac aaatgataac agcaatatat
    27541 catcaatcaa cctttttaat ctatctgatt cgctttctat tatttctaag aatctatttc
    27601 tagtattcac atctatattt tcatttgact ttagtgtttc aacaaaccca cttatagatg
    27661 taagtggtgt tttaagttca tgacttacat ttgcaacaaa atcacttctc atattttcaa
    27721 gtttaacttt tttagtaata tcttctatat ttactatcga acctattatt acgttgttag
    27781 tattctgaag ataaactggg tctaccttta tcttatatac gatatcatct ttagtagtaa
    27841 tattagcagt ttcattatct ttagaaccaa taaattgaag tatttgtttt aatatttctt
    27901 cttcttttat tacaacatta atattatgac cttcaactaa ttgatttggt tcactcttta
    27961 tcatttcttt tgcttcatca tttatcagaa gtatatttcc atttacatct atagccaaaa
    28021 ttccatgaga tatactcttt aatatagatc ttaactgtaa atgtttatac tgtacttctt
    28081 ctaaggtttt atccatattc tttatcatat gattaaaatt tctagctaat tcaccaagtt
    28141 ctcctttggc tgatatgtta agcctagcat gatattcatt attacttact ttttttgaga
    28201 cgtatataaa ctcttttaaa tatttcctta atgttattgt atatcttaca gctaatataa
    28261 caatggctat ggacaacata acaataaaaa aatatatact atttaaatct tccacaagat
    28321 aacactccta aaatataacc tttttaatct attttatacc ctacacctct tatagtctct
    28381 atatattttt ccgatttatc ttcatcttct attttttttc ttaaatatct tatatgaaca
    28441 tctactgttc tagtttctcc atagtattca tacccccata ttttatccaa aagataattt
    28501 cttgaaagta cttttccttt attttgaatt aataatttta acaattcaaa ttccttaaga
    28561 gttaactcta tcttttcaga gcctttggta acttcatgtt ttgataaatc tagttttaaa
    28621 ttgcctgtag taagtatatt gttttcttca cctaagctag tcaaattata tctccttaaa
    28681 acagaactaa tcctagctaa caactctttt atactaaatg gcttagttat atagtcatca
    28741 gcacctattt caagcccttc aaccttgtca ttttccatat ttttagcagt aagcattata
    28801 acaggaatat tttttaagtc cttatcactt cttatttttc tcaaaacttc tattccactt
    28861 atatttggta acatccaatc taaaagtatt aaatctggtt taatttcctt agcctttata
    28921 aatccgtcaa atccatcata tgaataacta acttcgtaat ttgacacctc caaattgaat
    28981 tttaatagct caactatatg catttcatcg tctataacaa gcactttagt attcattaaa
    29041 aagctcctct ctattttatc tgtagtaccg ttcctattcg ttctgatgcc ttattatgtt
    29101 ttctataaga gtggaattta tctgctctac aactagtgca taaatttaaa tttattatat
    29161 tttctttttt aactccacta catctaagca tatactcatt aattttccat aaatctaaat
    29221 agtaacttcc ctcttttatt atatagaact tttcatcatt atttgtaaga attgtgttaa
    29281 atttttctac taaatcttca gacacttcat agcaacatgg tccaattgat ggcccaatta
    29341 tacatactaa atcttcagga actgttttat agcattcaga cattaatttt attgttttat
    29401 gacctatatt actaaaagtc cctctccaac ctgcatgagc cagtcctatg gctttatttt
    29461 tagcatctat aattgatata ggtacacagt ctgctgtaaa cagtaaaagt ggtacttttt
    29521 ccaagtttgt tataagtgca tctccatctc ttcttttccc tatagtatct ttattgacta
    29581 tattaactat atctgaatgt atttgagaat tactagttat attttcaaat gtcaaatcac
    29641 attctttaca tacttttaac atatcttctc tattttttgc atctatattc ttacatgtta
    29701 taactagatt tacagaattt aatttttcat caagttcttc acaattacca cttaaattaa
    29761 catactcttt aatatcttgt acatttttta tatttatata atctttcatc atttgtctcc
    29821 tttttctatc agtatacttt taagttcatt tacaaaagta tttatatctt taaattgtct
    29881 atacacagaa gcaaatctta cataggcaac ctcatctaac tctttcaatt tatccattac
    29941 catctcaccg atttttttgg tttcaatttc ttctataaaa catttattta tttcattttc
    30001 aatatgtaca acaatacttt caatctcttc aatagaaaca ggtctttttt cacatgcttt
    30061 tagcaatcca tattttatct tttctctatc aaaatattct ctactattat cctttttaat
    30121 gaccattaaa ggagttgttt ctattttctc atacgtagta aacctctttt tacatgattc
    30181 acactcacgt cttcttctga tagattttaa atctgtatgt ctagaatcta ttacctttga
    30241 ttctttataa ttacaataag gacattgcat ctatattcct cctttgttta actatatctc
    30301 aaactcatct aagcttaatt ctgaacctat atttactatt attgtatcac aacctatttt
    30361 aagtatatca ttccaaaata taacttcttc atcccctcct cttgaaaaaa aacttctact
    30421 tccatctcca aaaatggtaa atgagactac cttaccttcg tgaatatcca tgtctatgtc
    30481 tattataaac cccatccttt ttccattttt tacatttata atttcttttt ccattatatc
    30541 agaaactcta atcatattgt actcaccctt tctttaaaaa taaatatgta tcgaagtaaa
    30601 aaaaaatgac ctatataggt catttaaatt aaaataatgt ttacagtcca tggattactt
    30661 atacatattt tctcatattt tttaaagcat ttttttcaat tcttgatact tgtgcttgag
    30721 atataccgat ttcatcagca acttctatct gagttcttcc tttgtaaaac cttaaatcta
    30781 ataccaactt ttctctacta tttaatttct taatagcttc tttaagtgat atttcttgca
    30841 accaattttc atcagtatct tttttatctt gaacctgatc cataacaaat attgcatctc
    30901 cattgtcttg atatactggg tcaaacagag atattgggtc ttgtatggca tcaagtgcca
    30961 ttacaactga ttctacttct aattctaatt cctttgctat ttctgatact gtaggttctt
    31021 tagaatttgt tctaattaat ctttctctaa cttgtagtgc cttatatgct atatctttta
    31081 atgacctact tactctaatt gggttattgt ctcttagata tcttctaatt tctcctataa
    31141 tcataggaac agcataagtt gaaaacctta cattttggct taaatcaaag ttatctatag
    31201 cttttataag accaatacaa cctatttgaa ataaatcgtc tatattttct cctctgttgt
    31261 taaacttttt tattacactc aagactaatc ttaaatttcc tcttacaaac tgttgtctgg
    31321 cttcttcatc accatttttt atttgtaata aaagttcctt catttgctta tttttaagaa
    31381 ctggaagttc tgatgtatta acaccacata tttcaacctt attaacttgc atatattttc
    31441 agtcctctct caaaagtatt catctattga aattatttac atttccaatt tttttatact
    31501 ttttaagaag aattaattta acattataca aattttttca tttctttttg caaccttgag
    31561 attattttct tttcaagtct agatatgtag gactgtgata ttccaagcat tccagcaact
    31621 tctttttgtg ttttttcaat acctttatca ataagaccaa atcttaattc cataatttgc
    31681 ttttctctgt cacttaatct gtcaagtgcc ataaccaaca aatctctatc tatttcttct
    31741 tcaattattt tgtatatttc atcattttct gtacccaata catcagataa taaaagttca
    31801 tttccatcta aatctatatt taaaggttca tcaaatgata cttctgtttt ctttttatta
    31861 ttttttctta agtacattaa tatttcattt tctatacatc tcgaagcata agttgccaat
    31921 tttatatttt tattcagttt aaaagtatta actgctttta tcaaacctat agttcctatt
    31981 gaaatcaaat cttctacatc tatacctgta ttttcaaatt ttctcgatat gtagactact
    32041 aatctaagat ttctttctat taaaattgac tttacacttt catctgtttc tagcttttgt
    32101 aaaagctcca tttcttcttc tggtttcaat ggaggaggaa gtatatttgc ccctcccata
    32161 tagtatattc cctttggctt tattattttt aatttaatac ctaacatagt aataaagctt
    32221 attattcttt ctttcaatcg taacattcct tgtccccctt aaattttcac ctaaaatcca
    32281 ggcaatatat ttggattcat tattgctcca tattctctat cattaaaatt tgaaatacca
    32341 agtattatat ttcctatctt ttgctcatct acttctatat agtcagcttt taagcctatt
    32401 attatgcttg tcttattact tccagcatgt ttataaggta ttattctaac tctacctgaa
    32461 gttttatcat ctaaacttcc tataatttct tgtgctttct tcatatctat atcttcataa
    32521 ttaatattta atagtttttc tggaataaat ccttctaaca cactagactt aactattatt
    32581 acatcacttt gacttattgg gtcttttaac aaattaccac tatctactaa agctttacag
    32641 caaaaacttt tttctagtaa gtttatattt atagtctttg taagctcctt aatgtactta
    32701 agcattttca aatctttata aatgtatttt aataattcac aactcacata agtacatgca
    32761 attaagaaag atatttttaa gtgacttatt cctgtaaaat aaattataaa ataagtgctt
    32821 ccagaaataa aaatgtttac tagataaaaa actaacgcta catgaacata atcttttttg
    32881 ctcttgcttc taaatgaaat taaagttatt atgctcatga ttattatttt aaatggtaca
    32941 gtaaatagta tattcattga tggatacaaa taagcaacag aataggcact tcctaaacta
    33001 gcccccaata acttattttt tttaggatta tatcttttag taagaataga agtacaactt
    33061 ataataatat aatttattac taggttttct ataacatagt actcaatata caccatgtat
    33121 ccccccttaa aacctttaaa catattataa gatagtatgt acaaaatttt atgtcacttt
    33181 tgatggtcga atccaaaaca aattctattt aaaaagaaca atgatatatg tcttatactt
    33241 tatgtcgtca aaagatattt ttttaatgcc aaacagatag acttttttgt agaatccaat
    33301 atatctaggt agaagttatt cgctttactt ttggtatatt tataaaaaaa agactacata
    33361 atttaataat atatcaagta aatcttttac ttatataaaa tcaaattata tagtctgtaa
    33421 attcaaatat aaattattgt gctagtaatc catttgcata ttttgcagat tcatttagtg
    33481 cttgttctgg agttatgtct ccagctatca tcatttgaag ttgtttccat aaatattcat
    33541 atatctctac tccatgaggt ccaactgtca atggtctata catatgttta tctcttgtca
    33601 ccatttcttc aaatcttggg tctccttggt atttttcacc tttagcaact ggagctctag
    33661 gtatttcttt gtggaaagct tccattgatt ctttgcttaa catatactca agaagtttaa
    33721 atccaagttc tttattttta catgctgaca ttaatgttaa atcatctact gaagcaaaac
    33781 ttccaactgt cttatcttct aatgatgtta catatcccca gtttaaatcc gggaatgatt
    33841 tatcaaatgt acttgtagca gcagaggata gcattatagt aaatgcagct tttcctggtc
    33901 caaatacact ttcaatcatt tcattactat cttttgataa agcatcttct ggaatatact
    33961 ttttcatatc atttataaag tttgcagctt tcaagccttc tgcattatta aatttaactg
    34021 attttaaatc atcattatat atatctccac cagcttgcca taaatacgga taccagttcc
    34081 agtttaagct tccaaatact ttagaacccc aaccttgtgc aagaccccac tggtcgattt
    34141 ttccatctcc atcagtatct tttgttgctt tttcacagat tcttttaaaa tcatcccatg
    34201 tttttggagg tttttctcct aatttttcta gtatatcttt attgtagtac aatacgcctg
    34261 gattagcagc ttctataggt aaaccataaa taccacccat catttttgca tcatctaagt
    34321 atagataatt atctgaagtt cctgattttt ctaaataagg tgttaaatct tctactgcac
    34381 ccatttctat aaattgaggg aacatctctg catacatgta tcctatatct ggaccttcac
    34441 ctgcacttat tgctgttgca tatttttctg cgtagttatc ccatggtact atctgaaatt
    34501 caatttcaca gttattttct ttttcaaatt tttcaaatat cggcttccat gcatctgcat
    34561 catggtctgt taatggtgca gaccatacaa ctaatttttc tttaccctct ttgcctttag
    34621 aatcttcttt ttttgaacat cctgcaagaa ttgatactga tagaatccct accataacta
    34681 aagaaagaac cttttttagt ttaatcatgc ttaatcccct ttcagacttt aatttgtctt
    34741 tttcctcaaa tgtttacatt taattcagat ttaatattaa caaataagac tactcttgtc
    34801 taatcataaa aaactatact aactcctata actatatttt ttttctatac ctattagatt
    34861 taattcatac taaaaactta ctttttaaat tttatcaata tttaaaaata tttttaagtc
    34921 tagccacaaa ctaactatct aaattgaaca aaataaaaag aagtctattg acttctttat
    34981 aagcttacat attatcttct tcttcttagg aatgtaggta tctccatgct ctcatcatca
    35041 tcttcttcaa ttatacttgc ctttttagga ggctctattt tttcctcagc aattacttct
    35101 tcttcaattt cttttacagc ttgttttact gttgtattta atgaagaacg tatgcttgat
    35161 ttaggtttag tatctaaatc taaggcacca ttttgtaatc cttcaaatcc tgttgcgatt
    35221 actgtaatca ttatttcatc acctaaatct tcttttatag aagctccaaa tataacattt
    35281 gcttctgggt cacaggattc cataactaaa gttgatgcct cattaacttc aaataatcct
    35341 aagttaggac cacctgtaac attaagaagt actcctttag ctccttgtat tgatgtttct
    35401 agaagtggag attgaatagc ttgtcttgca gcatcaattg ctctagtttc accactagca
    35461 ctacctatac ccatatgagc aagtcccttg tctttcatta tagtagtaac atctgcaaag
    35521 tccaagttta ttaacccttc aactgctata aggtctgaaa ttgattgtat accttgtttt
    35581 aatacatcat ctgcaactgc aaaagcatct aacattgatg tatttttttg tactatctgt
    35641 aaaagtctat catttggtat cgttataaga gtatctactt ttgatttaag ttctgctatt
    35701 ccaccttcag cgttcttcat tcttatctta ccttcaaatg caaaaggttt ggtaactaca
    35761 cctactgtaa gtatccccat ttcttttgcc aagcctgcaa ccactggagc agctcctgta
    35821 ccagtaccac cgcccattcc ggctgttaca aagaccatat cagctccttg aagtaacttt
    35881 actatttcat ctttactctc ctcagcagct cttttcccta cttctggatt tgctcctgct
    35941 ccaagtcctc tagttaattt ttctcctatt tgaactttat attcagcttt tgatgtatat
    36001 aaagcttgtt tatctgtatt tactgatata aattcaacgc cttttagttg agcttctacc
    36061 attctattga cagcattgtt tccaccgcca cctacaccta ttactttaat ttgtgcacat
    36121 tcttctaatt ctacgtcaaa gtttagcatc ataaaccccc ttctctcatg attcaaagtt
    36181 atcgtatgta ttaattatat cattttcttc ttttattttg ttaaccttta agtaacatat
    36241 tccacaaaaa cgtaaatttt cctttttaaa tttcttactt atattgtcaa atattactct
    36301 ttaagtataa aataatttac gtatatatta aatgctcttt aatttttacg ttttttgttc
    36361 ataatattac taataatata tcgtctaatt atagataagt tattaaacaa tctcatacca
    36421 aaaactagta cagcaacata gtaaagagaa actcctaact tttctcctat ataagtcaat
    36481 aatatagcca atatagcatt acctatgaaa ccagtaataa aaattacatt atcatagtta
    36541 tcttcaaaat tggattttat cgctccaaaa atagaatcca ttattgcaag aatagctact
    36601 gacatatata tggaataatc catagaatat gtaaatggaa tatagtaacc tactactaca
    36661 ccaaatgcta atcctcctaa aacccacaac ataaatcttc acctctttat tttactttga
    36721 aacacaacta cattacaatc ctttttatta atttttttta ctttttcttt atttttttgt
    36781 atttttcgtt ttattttgca aataaattca ctttattccc attattttcc tgaactttta
    36841 tattaattcc atatatatcc ttaagagatt tagcatatga ttctggagag tttatagctg
    36901 cactcaataa atctatatct cctatagctt ttattataaa tggttgtcca tatgtagtat
    36961 catttactgt aatagtagct cctgaacatt ttatcttact tgttgctagt actctttccc
    37021 catttataga aattgctctt gctccagcct tttttaaatc atttaaaact ctcaaaatat
    37081 ctatatcatg tataatcaaa tcatttggat tctgtccgtc ttttaactct ctctcactat
    37141 ccctcatagt aatagttatg cctggccctg taacagttga ataaccactt aattctttaa
    37201 cttcttcaag ctctttttgc ataagtgttt ggatagattc atttccattc ttttttgctt
    37261 ctttatattc attcaaagtt tttttgttgt ttttaagagt ttcttttaaa ttttttattt
    37321 ctttttttgt attttctacc tcactttcaa tactttcagt ttgacctaat gttatgtata
    37381 ctctatttgg gtctagtgat tttatataag ttgatatgaa aatgcctaat atgaatgctc
    37441 ctaatataac tattttcttt ttcatactat tatttcccct ctgctttgtt tatatcacta
    37501 tgaccattta tttctatatt gtcttctttg gtcactttta ctttggcatt ataatatgtt
    37561 tctatttccc agacaatacc atactttata ttaagtgccg aagccaatgt atcagaatca
    37621 ccaattgctt ttattataat tggttctttt atgacagtgt cattcataca aagcttgtct
    37681 tcttttaaat acatatatgt attaaaaact attctctggt cgtttataga tatggcactt
    37741 gcttgtgctg aatttaattt atttatcatt gacaataata aatcataatt atatagtata
    37801 ctatcatttt tatcagagtt tcctaagtct tttgtagaat ttatctcaat ttttatgcct
    37861 gttccttcaa catctgtata tccagctaat gtttcatatt tttctatttc tgacttaagt
    37921 atgtcttgtt ctcctttatt gtttttgcct ctataagtct ctatatcttt cttcacacta
    37981 ttaacttctg attgtagatt ctctttttct gtttttaaag atttaagttc ttctgtaagt
    38041 tgctctcctc ttttaaaagt tgtcatccct ctattttcta tattaataat tttaagttgt
    38101 aaactaacaa gaacacccaa tacaacactt cctatgatta tacttttatt tataaatctt
    38161 tttttcaata tatcacttcc ttacaattgt ctatccttct ggactataca ctgccaactt
    38221 tccatagtta agatttatag tccctccatt agtattttta ttttgcaggt caatcagaat
    38281 tttacttacc ctagatatat tataatctaa gttatcatca ttagaaagta agatttttat
    38341 attacttctt gtaagcattt ctatattgct ttcttttttt aagtttacat aatttatttt
    38401 tctataaatt ccttcttctt ttaaataatt taaagtttta aatacattct ccttagtttt
    38461 ataattttta aattttatag atttattatc atcaacgcta taatctacat ctactatcaa
    38521 gtctttttta ctttcattag aacctcttag ttcttccaat aaatttcctt ttttatctat
    38581 ataacaataa ttatcttcat cttttaatac tgcaaatatt tctttttctt ttaaacttat
    38641 aattatctta ttgggaagtt ttctttttat ttccacattt tctatatatg gattttttat
    38701 aagtttattt ttcatatctt taaaattgta tgcaaaaata ttttcattta gatttatatt
    38761 tagttctttc attatatttg atttggtcac cctcttattt ccaattacat ctattttctt
    38821 tacatcaaat aaatcacttt ttacaattat acatatacaa aaagataaca taagtataaa
    38881 aactaaaact atcatgacat tattcgtatt taactttctt ctttttttca aatataatca
    38941 acccctttgg ttaataaata cacctttaga gcttgttttt cctacaaaaa aattataata
    39001 tttaaagtca aatttttgca ttttattaca taacatccaa ataaggtatt aaattttata
    39061 aataaatcaa tatttcatca aaataaacat agtatactac atactattta tatatttaaa
    39121 tctgtataca tacaaataaa cccctaattt ataataattt agaaaatcta atatattata
    39181 aattaggggt aaatatttac ttatcttttc tttattccta ttaccttagc ttgaccttct
    39241 atacttggag tcgtttcttt ttttatttct tttacttcct taataacttt ttcctttttt
    39301 gtttttttag aagttgactt ttgtgttgaa ttgtatactt tcattatctc atcatatata
    39361 aggtctatgg cttcaggctt acctatagtt ttacttgcat ttgccatatc aactaaaagt
    39421 tctctatctc ctaaaagttt aaatactgct gtatttaggc tctctggagt tagatttttt
    39481 tctaaaatag caattcctgc cccttgtttt tctatactct tggcattata ctcttgatga
    39541 ttttcagcag tataagcttt aggtattatt atagatggct ttccaagagc cgttatctca
    39601 gctaatgaaa ttgctcctgc gctacctata accaaatcac ttgctgcaag tgcatttgcc
    39661 atatcttcta agtaaggcac aactttttgg tatggtttaa gatttatatc gctaatactt
    39721 cccataaatt catcataata gcttttgcct gtagcaaata taaaagctat atcttcattt
    39781 accatattct ttattacaag tctcattgca tcatttattt ttcttgaacc tccactacca
    39841 ccatagcaaa gtaccattct tttttcgtca cttattgata gattctttct tgcaatattt
    39901 tttcttgata ataaaatttc ttttctaact ggatttcctg taaaaactaa tttatcttct
    39961 gctgcctctg gaaatctttt atgcgaatct tcaaaacttg taagtacctt tgtaactgtt
    40021 ttagataaaa tcttattagt tacaccagga aaagaatttt gctcatgtat tatggctggt
    40081 attttcccca tagatgcatt aaataaaaca ggtccactaa catatccacc agttcctata
    40141 actatatctg gtttaaattt cttaacaatc tttcttgatt gctccaaacc tttaaaaagc
    40201 ttaaaaactc tttttacatt atcgaaatct atttttcgct taaaaccttg aactgttaca
    40261 gtctttaatt caaatccata cttaggaact atttctgact ctattccctt ttccgtccca
    40321 acaaaaatta tctcagcgtc tggatgctca tctcttattt tgtttgcaat agctatagct
    40381 ggatacacgt gccctccagt tccaccgcct gataataaaa ctttcatcaa atcatcatct
    40441 cctgttaatt aattttgaca tgctttgaga tgtttaacac tattcctaca gctcccataa
    40501 agatggtgag tgaagttcct ccataactta taaatggtag tgctacacct gtagctggca
    40561 ttgatgatgt cgcaactgct atatttaaag ctgcttgtat tccaatttgt gcacctatac
    40621 ctataacaac catacaagca aatacattag aagtcttcaa agctattctt acacatctgt
    40681 agactaaaac tacaaatagc ataataacta ttatacaacc aatcaatcct aactcttctc
    40741 ctattatagc aaatataaag tcattttgtg gctctggtat ataaaaatac ttttgtttac
    40801 tctttcctaa gcctagacca aacaatccac ctgaacctag tgcatataga ccttgtatta
    40861 cctgataccc cttaccaaga gggtcttgaa aaggatctaa aaatgatgta acacgactaa
    40921 gtctataggg ttcagcaatt actaatgcag caaataaagc agccccactc cctatcatag
    40981 caaatacaat tttcatatcc attccagcaa caaatatcat tacaaaagta actagaatta
    41041 cagtacctgc tgttgacaaa tttggctgaa gtattatcaa cgcaaaaaat atccctggaa
    41101 ctacgagaag tggtacaaca ccttttgtca aagattttat tttatcataa tttttttcaa
    41161 ttaattttgc agttaatatt attgtagcaa actttgcgat ttctgcaggt tgaaatgtta
    41221 aagctcctat tcccaaccat ctttttgctc cgtttgcttc tatccctaaa ggggtcaaaa
    41281 ctaacaataa taatactact gctatagctc caattgctgt agcatttttc ttccaaaaac
    41341 tataatctat tcttgatgta ataatcataa ctataaatcc aagtacagca tatattacat
    41401 tcttttttag aaaatagtac gcatcattgt gtttaaatga agattgtata aaacttgcac
    41461 taaacaccat aactattcct acaaatacta aaagcatagt agtgtaaaac actactccat
    41521 caaattcagt cttcatcctt atgtcaattt gttttttcaa attttcttta ggcatccaac
    41581 taatctacct ccattcttcc atttaagtaa gtttagaggt aagagattat tttaaattgt
    41641 ttacattatc tttgaagtct tttcctctta cttcaaaact ttcatacata tcccaacttg
    41701 cacaagctgg tgaaagaagc actatatctc cactttttga aatttcataa gaagtcttaa
    41761 ctgcttcttc catatctttt actatatgta tgtcattaaa tcctttattt ttagcacaat
    41821 tttctatatt tgatgcagtt tctcctaata agaccaatga tttaacatat gactttgcag
    41881 tttcaagaag ttcatcaaaa ttacttccct tatccatccc ccctgctata agtattatag
    41941 gtctatcata agactgtata gcttttatag tggaatctgg attagttccc tttgaatcat
    42001 ttacatatat tacattgtct aaatttctta caaactcttg tctgtgttcc actcctttaa
    42061 atgtcataag tacatccttt ataacttcta aatcaatttt gcagacatat gctattgcta
    42121 tagctgccat acaattttct aagttatgac ctccaggtaa acttacatca tctttattta
    42181 gaaatttgat tttatcatct atatctatta ttatgtcatt attttctaaa tatactcctc
    42241 catttacttt tttagttctt gaaaagtaaa ttactttggc attgcattta tcagctaaag
    42301 attttactac ctcatcatca tagtttaaca cacagaaatc ctcaacagtt tggttcataa
    42361 atatatttgc ctttgcttct atgtattttt ccatagtatg gtgtctattt aagtggtcct
    42421 ctgtaatatt taatattgcg cttactttag gtctaaattc atctatactc tcaagctgaa
    42481 aactgcttag ttcagttact aacacagact cttcacttga agtttctata gtatctatta
    42541 caggatttcc tatattacca actacatatg tatctcgttt tgctcttgaa aaaatttctc
    42601 ctaccaaact agttgtagtt gtctttccat ttgtacctgt aatccctata aaaattggat
    42661 tattcgatag tttaaaagct aattctacct caccaattat atacttgcct gaatttttta
    42721 atttcaatat gaatggtagg tctagtggta cacctggaga cactacaacc atatctatat
    42781 catctacatc ttctgggtga tgtcctaata tgtattttat gtcatttata gatttcaatt
    42841 catcaagtat atttctcaat ttattttcat cttttatatc atttacgatt atacttgcac
    42901 ccaatttatc taaatgttta attgtagata taccagtttt tgcaagtcct actaataaaa
    42961 ctttttttcc ttttaagtcc atttttcatt ccccctagcc ctaaaatact gctattatac
    43021 ttatccaagc taaaacaact gttataatcc aaaaaataaa tacaactctt gtttctggcc
    43081 aaccacactg ttcaaagtgg tggtgtattg gagccatctt aaagaatctc tttcttgttg
    43141 ccttaaaata tccaacttga atcaaaactg atagagcctc cgcaaaataa attcctccaa
    43201 ttataggtat tataagcact gagttagtta gaactgaaaa tgctacaact gcacctccta
    43261 atgccattga acctgtgtcg cccataaaca ctctagccgg atatgaatta aatcctaaga
    43321 aacctaaaca tgctccaaca gttgctgctg ctaaaactgc gacttctgta tttccagcaa
    43381 tagaacttgc aaatagcata aagaatacag aaactattaa tgttactcct gatgctaatc
    43441 catctaatcc atcagtcaag tttacagcat ttactattgc tacgattata aacatcatta
    43501 ttggtatata taatattcca acatttatca caaaatctgt aaatggtatc ataagttgtg
    43561 aagcacttga tgatgatgta tactgataaa aagcaacata aaaagataat gcaacttgaa
    43621 ggattatttt ttgatatgct tttagtccaa gtgatctttt tagctttatt tttataaaat
    43681 catctaaaaa gccaataaaa ccaaaacctg caatacatat aagacctact gccatatcat
    43741 gactaacttt tactcttgta agtccagtta ttagaattgc aacaatcatt ataattccac
    43801 ccatagtagg tgttccgttt ttagctagat gtgtttgggg tccatcatct ctaactgtct
    43861 gaccaaattt aaattttcta agcattggta taaatattgg tcctattata attactatta
    43921 aaaacgcaat caatgcggtg tacgtaagct ctgttattcc taacatcata aaactcctct
    43981 cccttgtcaa ttaactcatt agtttaagct tatttattta gatattcgac tattttttct
    44041 aatctcatgc ctcttgagcc ttttactaaa atagtgtctc ctgtttttac taattcattt
    44101 aacttgttaa acacatcttc tctattctca aagtgatata tattggctga attgaatcct
    44161 aattgttttg cttcttctcc aataaacact gaattttcac ctatagttat tataatatca
    44221 gtattattca tagatgattt tccaactaat ctatgaccat actctgaaat ttcacccatt
    44281 tctagtatat ctccaagtat cgctaccctt ctacctttat atcttccaag tatctttaaa
    44341 gcagcatcca tagaatctgg actagcatta tatgaatcat taattattgt taatttttca
    44401 ttttttatta tgtctagtct catttttgtc cctttaaaat tttttaaacc tttttttata
    44461 taatctaaag aaatatttag acacaaacca actaatatag cagacattgc attatatata
    44521 ttatgttctc ctattgttgg tataaatatt tcctcttttt tcccatttat tacacatata
    44581 aatgttaaac tatcctcttc catagtataa ctttcacaat aaatatcatt gtttttatta
    44641 aagccaaatg tttttaactt atatacatgt tctttttctt ttaatgtaga taaaaactta
    44701 tcatctccat ttacaattaa agtatttgtt tcatcaaagt ttgaagtaat ctccatcttt
    44761 gctttcaaaa taccctcttg tgaacccagt ttttctacat gtgataatcc tatattcgat
    44821 atgactgcaa ttttaggatt tactatatcc actaaatatt ttatttcatt gaatccagac
    44881 atacccatct ctattacagc acactcatgt tctttattta gattaaataa agtcaatgga
    44941 actccaaaat gattatttaa gtttttttca ttttttagta tatttaactt tgcagatatg
    45001 gcagagtaaa tcatatctct agtagtagtt tttcccacac tacctgtaac acctataaat
    45061 ggaatatcaa atttttcttt atagtatttt gaaatatctc ctagagccaa agatgtatct
    45121 tttacctcta ttaaatttat atccgaactt tctaatttta ttccattact ttcatttttt
    45181 ataaaagttt tacatccact atcatatgca ggcttcataa atgtatgccc atctaaattt
    45241 tctccaacta tggctacaaa tgcattttgg gcacttgcct ccctgctatc tataactata
    45301 tcacttacac agtcattata atctccatat attaacttcc cattagttgc aagtactaac
    45361 tcttttattg ttaagcactc cattattaaa ctcctccttt aaaaccttag ctatattctc
    45421 ttagcaacaa aaggcaatgt ataccgttat atatacattg cctacgataa ctcttaactt
    45481 tataattata tactatattt ctgttttttt gaagatgttt atgggtatat gttaattatc
    45541 tgttactttt tagttttcaa aatatagggt tatacttgag tcttcattaa cttttactcc
    45601 aggttttggg aatatatcct ttacctttgt atcttctgga agttctatat ctgcatctaa
    45661 gtctggtttt aacttcgcat cctccaatgc ctttacagca tctcctattt ttagatttct
    45721 tacatctggc actttaactt gcttcttttc atactcagct ttttcttctt ctttatatac
    45781 tggtttaact cccaaatatt ttaaagagtc attcattatt tctttcacta ttggtcctgc
    45841 tgtagtacta ccaaatgcac ttactcctgt tggttcgtca acaatagcaa gaactactat
    45901 ttgcgggtca tcacaaggtg ctattccaac aaatgaacat atatactttc ctggagcata
    45961 cttaccatct ataacttttt gagctgtacc tgttttacca ccaagtctat accctggtat
    46021 atatgctatc tttcctccac cttcagttac aactgattct gcaatttcta acattttttt
    46081 agatgtttct ttagatataa cacttcttac tttttttggt tttactgttt cagttatatt
    46141 tcctttattg tcagtataag attttaccac tcttggttgc attaaatctc caccattagc
    46201 tattgatgat atagctgtta taagttgtat tggagttact gatatagatt gaccaaatga
    46261 tattgtagcc aattcaactg gtcctacatt tttttcgtta tacagtattc ccttagcttc
    46321 tcctggtaaa tctatacctg tcttatccat aaggccaaat gattctatat aatcatacat
    46381 ttttccaaca cctaatctgc ttcctaattc aacaaatact gggttgcaag agttttgtac
    46441 tgcttgttta aattcttgtg ttccatgagg tctgtaatgt ctccaacatt taatctttct
    46501 tcctccaaca gttacactac ctgtacatgt gaatttttct ccatctttaa ttactccctc
    46561 ttcaagagca ctggaagatg taataagctt aaatgtagaa cctggttcat atgtatcact
    46621 tactgctgga tttctccaca tttgataata gccttttatt ttatctttat cattatattt
    46681 ttcaagttct tcttgataat atggatatat tggcgttctt gagtcattag ggtcataatc
    46741 tggttttgat gctaaagcaa gtatatcacc tgttttaggg ttcatagcta ttgcagtaac
    46801 cttttttgca ttatttaact cataagcttt ctgtactgct ttttcagtat agtgttgaat
    46861 tacttcatct atagacaaca caagaccatt accttgtaca ggctcataat atttttccat
    46921 tccttgtggt atttctcttc ctgaggcatc agtacttact ataagttttc caggctttcc
    46981 ttttaacttt ttatcatatt gcatttctac accagatata cctgttgcat ctgaagaagt
    47041 atgtcctaac acatatggcg caaaattccc atatgggtaa tatctttgat tatcttctgc
    47101 tacccatatt ccacttaatt tagcatctct tatttgactt gccttatcat catctatcca
    47161 tctttttact tttacaagag ccatattttt tttgcttatt aaagcgtaaa tatctttata
    47221 atcttcatcc aaaatctcag ctaccttttc agctgcttct tttttatctt ctacttccac
    47281 aggtttacac caaacagtat acttagttac acttactgct aattctttca tatttctatc
    47341 atatatagtt cctcttttgg gttctattgg tatatctctt gtttgttgtt ctagtgcttt
    47401 tgtactcaac caatttccct tcataagttg taggtaccca gtcctaataa caaggcaaaa
    47461 aaacaatgca catgctagaa taagaacgag taccagcctt ttcttactta tcctctttac
    47521 ttttctcaaa tctattcccc ctagttatcc acatctatat actttatttg tccatctttt
    47581 ggatagtcca tattgagcaa ttccttagcc tttagctcaa tttcttttat tgatgttttt
    47641 tcagtttctt ttgcctttag ttcctctaat actatctctt tttttcttaa atctttttgt
    47701 aaataataga tatcgtactt catttccgag atttttgaat aaccacatag attcaatatt
    47761 attactgaaa aaattgcaat cagtaaaatg catttagctc ctattttttt cttatttctc
    47821 tttttataat tattcttttt tttattttta tattcattta gattatgtat tttataattt
    47881 tttttcaaat tctcaccccg atagtatata gtttaaattt tcctctatac tatatttgtt
    47941 attaatcata tttcttcctc taaaatttca tcgctaaatt aatacactat tacacaatct
    48001 aattgtattt ttttctatac acaacaaaaa cctataaatt cacttatact tttatatgaa
    48061 tctataggtt agatattaat ttctatttat ttttatcact tctagtattt ttagataatt
    48121 tcttccataa atataatatg taactaacta tctactctct gattcctaag ttctccatta
    48181 tattacttaa taccatctat atctatattt ttatatctaa attttcatta tatatctcaa
    48241 taacaaagaa catttcttat agtgttaatt gttttttaat tgctttacca gttcaacaaa
    48301 atatataata ctttttaatt aattatagta atcttatttt atatataaga ttattcttta
    48361 gccttataac tacttatatt ttttctgcta ctcttagctt agcacttctt gaacgtggat
    48421 ttacttctat ttcttcctca ctaggtaata taggttttct agttattatt ttcacctcag
    48481 attctttatc acattggcat ataggtaaat gttgtggaca tatacaatct gatgctaaat
    48541 gcttaaatgc atttttcact attctatctt ctaatgaatg gaatgttatt atacatattc
    48601 ttccaccttt attcattata gaagaagcat catttatcat ctttgtaatt actccaagtt
    48661 cattatttac ttctattcgt attgcctgaa aagttctttt agctgggtga ggtccatcta
    48721 ttctagcttt cttagggata gcttttttaa ttatatctac taattttcct gtagtttcta
    48781 ttggtttgtt tgctctttct tcaactataa atttagctat acgcttagcc cagttatctt
    48841 ctccataatc ttttattatc ttagttaatt catcttctgt ataagtattt acaacatcat
    48901 atgcagaaaa ctcacaccta acatccattc tcatatcaag tggtgcatct tgcatataag
    48961 aaaatcctct atcagcttca tcaagttgat gagatgaaac tcctaaatca gctaatacac
    49021 catcaatttt gtaaactcct attttttcta attcctcttt tatattttca aaattgctgt
    49081 gaacaaactt cactctactt tcatattcac tcaatctctc ttttgctgtg cttatagcat
    49141 ttttatcttg gtcaaaccct ataaataatc ccttatctga cagttttttt actatttctt
    49201 tagaatgtcc tgctcctccc atagtacagt caacatacac gccatctggc tttatattta
    49261 aattctctat acactcattt aaaagaactg atacatgatg aaattccata gttacctccc
    49321 ttaaattcac tttttaaact attcttcact aatattatgt ttatttttct ttgataaata
    49381 aacatgtgca attatgccac caataactcc aattagactt ataacttgtg ccattctaag
    49441 tggtcctaac attaaactat ctgttcttaa tccctctata aaaaatcttc ctattgaata
    49501 taaagttata taagtaacta taacttgacc ttcatatttt ttattttttc taaatagtaa
    49561 taaaactata aatattccaa aatcccatat ggactcatat aaaaaagttg gatgtacctt
    49621 tactccatca accattattc cccaaggtaa attggtagca cctccatgtg cttctccatt
    49681 aataaaattt ccccatcttc caatagcttg tgctaaaggc attccaagta taactgtatc
    49741 agccattttt aagaagttaa tatttttaat cttagtgtat atataaccag ctaatattcc
    49801 accaattaac cctccatgta tagcaagtcc accacctcta aaattaaaaa tttgagacat
    49861 attttgagca tagtaactcc aattaaatac aacataatag attcttgcac agattagtcc
    49921 aactggaatt gctattatag ctatatttaa tacatcatca tctttaattc ccactctttt
    49981 tgcttctttt attgctatta aagttcctaa aatcattcca catgccataa gtattccata
    50041 ccacatgatg tctatgccaa acagtgtaaa tgctactcta tccataacgt cacctctttg
    50101 tattaattga aaatatttcc aaagcaatat gctataatta caattaattg taattatact
    50161 aaattatgat aacacattaa tgttaattct acaaaaaata ttaaaattta ttctacaaat
    50221 ccctacacta tattatacta atataattac tataaaattt tttaaactga atctctcatg
    50281 actaaagtta caagtgtaca tagatatttt ttaatcaaaa agattgatgc atatatacat
    50341 caacctcttc tattccttat ctatagctct taaattttta cctcaattta tataaatata
    50401 ttttataaat ttgttttacc aaaataaaca tttaaaaaca taaataatac ttaattagtt
    50461 attcttatta tgattaagtt tctatttagg ttctacaata gaaataacac aatactcttc
    50521 tttaaaatgc tcttttaatc tttcttcaac ttcctcaaaa gtaatatctt taataacatc
    50581 taaataatcc aatagattta tatccttaaa aacataagat ataaaactat tacctataaa
    50641 gtttatagaa tcaaagcact taataaatga ccctattttt ttctttttag ttctctcaaa
    50701 ctcttctttt gataatcctt ctttttttga tttttctata taatcaagaa ttatttcttt
    50761 tactttttta ggctctttag aatctccagc tattatgcta aaagcataat ccacttgaga
    50821 cgaaaatcca gctccaaaat tttcatttat taaaccttgc atatacaaat cttcatagag
    50881 cttacttcct tttttaaata acatccctac aagtatatca gttacaatct ctttacgtaa
    50941 aagttctttc ccttttaaac caacattact atctttaaaa cctatgttga acataggcat
    51001 agatataggg aatttttcta taacctcttt ttcttttaca ctttctggtt cttctggata
    51061 aaatctttct atactcttag agagtttgtc tactttgtaa ttgtttgact ttttagttac
    51121 atctataact ttttctacat ctaagtcacc aacaacaaat aaagccatat ttcctggatt
    51181 atagaaagta ttataacatt tatatagctc ttccttagtt atcttatata tactatcaac
    51241 agtacctgct atatcaattc tagcaggata atttacatac attgccttca agcaattaaa
    51301 gtatacattc caatcagggt catcattgta catttttatc tcttgtgcta ttataccttt
    51361 ttccttttca acattttcat ctgtaaaata aggtgtttga acatagtcaa ttagatgttc
    51421 taaactctca taaaaatttt cagtagcaga aaataagtag gctgtcattg taaaattagt
    51481 aaatgcattt gcatttactc ctaattttga aaatttatca aatgcatctc ctccatcagg
    51541 ttgctcaaac atcttatgct ctagaaaatg tgcaatacct tcattcactc taattttctt
    51601 atcttctcca attggtacaa attctaagtc atttgaacca taattagtag ccaaaatagc
    51661 atactttttc ataaaacccc ttttaggcat aaaatataca tctaatccat tttgcaattt
    51721 ctcataataa acttcttctt tcaatatatc attaactatt ttttccatag acatctcctc
    51781 cattaatttc tcaagaagta tacagtatca agctctatat tttttatagc ttcaactata
    51841 tctttttttg taaccttttc tatactagat attatgtctt gtacttcaga atttgtcttt
    51901 gccatagact gagagaaaac aaaatcagac ataccaccta tattatcagt tatagatttc
    51961 atagaattaa ctaaagcaag tttactgttt tctaattctt catcagatat atcacctgct
    52021 tttacacttt ctacttgttt ttttatcaat tctacagctt tatcataatc tttagtttct
    52081 ataccagatg atataaacat gatactttta tacttctcta ttgaagagaa tatatagtaa
    52141 cataaacttt ctttttctct tacattaaca aataatttag agtgtggacc accacctaag
    52201 acattgctcc caactactaa agcataatat ttatctatgt ctgcataatc cacatttgct
    52261 ctataaccca taactaactt accttgagtt atttccattt gttcatctat aacttttacc
    52321 tcatccacat tttttataaa atctgctctt ggtatattta taatttcttc tctttcaaat
    52381 tttagatttt tacttattat atctacaact ttatcttcat caaaattacc ttctacaact
    52441 atatctatag gtgatgtttt aagtatgttt ttataatgtt catataactc tcttgaagtt
    52501 atactatcta tttcatcttc ataaccaaat tcacttacac tatatctctc tcctttacac
    52561 atagcctcaa tacatttatc ttgcgcatat tcctttttat catttattat tgattgtatc
    52621 ttttctctta aattctcttt ttcaatattt aaatattctt ctttaaaccc accatctaca
    52681 acaagcgtat tatttattac ttcattaaaa aattctacta cttcttcaaa tatactctca
    52741 tctaaatact tttcacttat gttaattact ttaaaactca atacttgacg ttctccacgt
    52801 tttacagcat cagctcccat agatgaacca tataaatcat ctaatttatt ggatattgct
    52861 ctagcactag gatatttagc gcttccactt gctattattg atggtattag agcatttttt
    52921 gtagtttctt tttcatccaa tagtctctga acatataaac ttataagatt cgatttaaac
    52981 ttttctgttt ttatcaaagt aagattaata ttattaccta aatttattat ttttttagta
    53041 ttaaccatat gtacctccta tttttattta aacatcaatt ttaaaattga aatttattta
    53101 ttttttaatt atatatactc acatataaaa accttctatt taattatatc ctttttatta
    53161 ttttctaaaa gcaatatttt tatttaaatt aaatgcaaat attatttaaa tcaatatgct
    53221 ttaaagtcta gtttacaagc ttgatatata tgatgtataa tcaatatgta tgtctataat
    53281 taaaacaatt ttgcaatcct atagattgat tgtttaaagt tatataaaga atataaaaaa
    53341 gaataagaga gaggacgatt aatatgaaat taggtatagt tggtttgcca aatgtaggta
    53401 aaagcacact atttaacgca ataactcaag caggtgcaga atctgcaaat tacccttttt
    53461 gtacaataga cccaaatgtg ggagttgtat ctgttccaga tgaaagatta aacaaactac
    53521 aagaattata taattctgaa aaaatagttc ctactgctat agaattttgt gatatagcag
    53581 gtttagttag aggtgcttct aaaggagaag gtttaggaaa taaattctta tcacatataa
    53641 gagaagttga tgcaatagtt catgttgtta gatgttttga ggatgaaaat gttgtacatg
    53701 tagatggctc tgtagaccca cttcgcgata tagaaactat aaacttagaa ttaattttct
    53761 cagatataga gattcttgaa agaagaatta ataaaactca aaaagctgct aaggctgata
    53821 aaactttagg ttctgaactt gatttattaa aatcaataat gtctacttta gaagaaagta
    53881 agtgtgtaag aactatggaa tttacagaag atgaacaaac attcgtaaat tcattggatt
    53941 tacttacatc taagcctgta atatatgctt caaatgtatc agaagatgat ttagctgata
    54001 atggagaaaa taataaatat gttcaacaag ttaaagcatt tgcagaaaca gaagatgccg
    54061 aagttgttgt agtatgtgca caaatagaag cagaaatttc tgaacttgat tctgctgaag
    54121 aaaagaaaga gtttttagaa acattaggtc ttgaacaatc agggcttgat aagcttataa
    54181 aatcttctta tgctttactt ggtttaattt cattcttaac tgctggtcca aaagaagtta
    54241 gagcatggac tataaaagtt ggaagtaaag ctcctcaggc aggaggaaaa atacattctg
    54301 atatagaaag aggatttatc agagcagaaa caatagcctt taatgatttg gttgagcatg
    54361 gtactatggc tgctgctaaa gaaaaagggt tggttaaatt agaaggtaaa gaatacatag
    54421 ttaaagatgg agatgtaata ttatttagat ttaatgttta aaatgattaa tcatatacac
    54481 tttgactatt atatataata actaaa
//
LOCUS       DAMJWO010000014        53555 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.015, whole genome shotgun sequence.
ACCESSION   DAMJWO010000014 DAMJWO010000000
VERSION     DAMJWO010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53555
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.015"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            349..747
                     /locus_tag="PC366_000917"
     CDS             349..747
                     /locus_tag="PC366_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2576456.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     ILMSIADYFNVTTDWLLYGKEKVNVNSSVKEDKEDYLHVTNDEMMILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
     gene            complement(964..1173)
                     /locus_tag="PC366_000918"
     CDS             complement(964..1173)
                     /locus_tag="PC366_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576457.1"
                     /translation="MCKLDSDGVIECCRAIDDFITALSNIKSLNMERLNTLTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(1205..1414)
                     /locus_tag="PC366_000919"
     CDS             complement(1205..1414)
                     /locus_tag="PC366_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2576458.1"
                     /translation="MDARKKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            1713..2132
                     /locus_tag="PC366_000920"
     CDS             1713..2132
                     /locus_tag="PC366_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2576459.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSIAEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKEKDLGKIEYNKNKDEKIDK"
     gene            2360..2815
                     /locus_tag="PC366_000921"
     CDS             2360..2815
                     /locus_tag="PC366_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576460.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(3040..3300)
                     /locus_tag="PC366_000922"
     CDS             complement(3040..3300)
                     /locus_tag="PC366_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576461.1"
                     /translation="MDKLITELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVQMGIMKTDVEEIKEDVTDIKGMLQNGV"
     gene            complement(3563..3916)
                     /locus_tag="PC366_000923"
     CDS             complement(3563..3916)
                     /locus_tag="PC366_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576462.1"
                     /translation="MFKFDKNKIEQIKQGRKVEMQYKDISDISIGQAKQDDDITNNFI
                     ANAEIYEMLLSQSSVNEASNISTFSVRKSGGESGMVEVYVALILRGRKTIEEVPAVIR
                     EQVRIRCKELEIPVE"
     gene            complement(3933..9110)
                     /locus_tag="PC366_000924"
     CDS             complement(3933..9110)
                     /locus_tag="PC366_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome condensation regulator"
                     /protein_id="HDF2576463.1"
                     /translation="MKQNKLLQRGAYFNDKNILIDDFDKRYNDYDFVEFFTGISNSTF
                     GLKSDGNLYACGDNTGFQLGLGKDSSERRMFSKVKIDNVKYVSCGSKHSVAVTKDGFA
                     YGAGTSNVGQLGVIESTVYYEFTKLPIDDVKTVACGYDFTFVLKNDGTLYSAGLNSSG
                     QLGLGDTNNRATFTKVNIDSVKDVVTYNQSVFIIKMDGTAHACGLNSNGQLGINSTLN
                     KSVFNKIEGMDNVKQIACGSSHTILIKNDGTMYTTGYNGVGQLGTGNNNNSIVFTLSS
                     INNVKYASCGNNHTMILKYDNTLFSTGQNNYGQLANANKDVASRNTFAKVNVENIKDI
                     KCGSQFNFLINGSKEIFVSGCNLAGQLGSFFHTTFLYEFSNVQSSNLDNYSGLLVNDD
                     YLYVTKDNSEFLNVKLSDNFQDYKKIELTDSNMFIVMNDGTLYACGLNNYGQLGLGDT
                     VNRSVMTKVDIDNVLDIKGNGNSTFVLKNNGTLYSCGLNSNGQLGLRDEVNRNIFTKI
                     EIENVKDFCVGSNYVIALNHSKEVYGWGNNPYNNIEKTSNYPYKQGISNIEKIAAYDY
                     SVYMINSEGKLYVSGYNYNYQLGKGNNSNQSKALVSQCRTNSTSSTSNGLRTLPKITN
                     VFPFYDGCAIIDEGGYVYLTGYHGYLRTLNSSPSISDYSRYGTFIEATNSNHNTYFIQ
                     ETDFSGIEKVIGMSNNILFFKKGSSYITGYPKTFGSTITGHRSYTSINSESSNLGSNF
                     IIYHSNSKLYGKGIANSGQFGNSTNIDGTSNYDTGLKDIKDIIVKGNTVVVVDKNNNI
                     YVTGMNQNNKLGIGEYNNEPVKKFTNITEQSNSFIFMDDIKEITTSRNTMFIVKNDGT
                     AYATGNNSSGQLGLGDTINRNKFTQINLDNIKKISTSIDGNTTFAIRNDGTLYSTGLN
                     TKGQLGLGDIVNRNTFTKVNIQNVRDVVLGTTHSHAIKDDNTLYSCGENTHGQLGLGS
                     ESNHPDVLTFTVNNITNVRDVYCSDTTTFIVKDTNIAYCCGYNNNSQLGMGNTTDQYS
                     FIKCMENVKEVIPNEINTYIITIYNTAYSTGLNTDYCLGLNSNSNQSSFSEIPISNVV
                     KVAPNRNNAVLLLTSEGDVYTAGKCSNGSGTGSETPEKIKKIASKAKDIGMNYRCGHY
                     VSDNGDLYGTGFNNNGQLGVGDVTKRDTFIKTNTRVKKILPLEYANIAIKDTNDIYIC
                     GLNNYGQLGVGNRYDSRNNDNRIFNYKHMNFVMGDLTSIKNRHNFILLNNKIVIPTTK
                     DIDYGLVLGNLYKGDLYTELPYEDIKEVSISKTHIIILLNDGTMYGCGTNYHGELLQD
                     LSINQVDEFVQINVSDVKHVSCGDNFTYFIKSDDSLWSIGKNSEYQLGIGHNNPVTEL
                     QRITTISSCKEVHCGKNYTLVVTTGNELFVQGYNDKGALGLGSDSENTIIKFFTKALT
                     DIREIKSYGSDHILVLKNDNSVWVTGKNRDVYKIEQPVEFLKEFTIVPISEDVNTVKD
                     VLATDNTLYIISEVGTTNAAIEITEKSISSIKIKIQDPNKDISRIEMLINGESVKSVS
                     DLTTEKISFEVPPDKIKIGENKILFRAYCKGDDLYASLFIFKESTGNSIIKDSYVMIG
                     NRMYKVVNTTSNEQDITITLDRGLEEDLNLGDPIYQLINKTKVQVKINKSDLFKDMKL
                     VEIKKSDSSYQEIYELEEANIKSAQPKIIVEKGDKWTAIKRPSMIFRYDAENNEPQA"
     gene            complement(9132..10118)
                     /locus_tag="PC366_000925"
     CDS             complement(9132..10118)
                     /locus_tag="PC366_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDF2576464.1"
                     /translation="MEEKFYIILTKIGREKIANATALGELVGLTKFQVGDSNGEYYEP
                     TEEQTALKNVVWEGNINSLRIDEKNPNWIVIETILPGTVGGFMIREAAVLDNENNIIA
                     IGKYPETYKPRAEDGSIKDLVVKMILQLSNTSNVTLEVDPTLVFVTQKDIQDLDDKFD
                     KNIKEIKVKIGDTDILTTDSKDLSGAINEVVKKIENISFDDVISGQIQTDISVLKNSY
                     NKLSEKVLDILIYLELESEVTVDEAGYWYDTLANGNNIVAIEGLKLDLNRKCITGEIG
                     NVIFRDVVLPFSANRVRYIHDMDNNFVETKSSNTYLKEQKDITLSKYSYEIR"
     gene            complement(10119..10817)
                     /locus_tag="PC366_000926"
     CDS             complement(10119..10817)
                     /locus_tag="PC366_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HDF2576465.1"
                     /translation="MKLIDKLPSFDRNYIVEEIQGAYDTELNILKEDIDDTFNQLFVD
                     TATWGLDMWEDILCIEKKELDFDTRRSNIKAKMRSRGTSTIEVIKSICEAYTKSETDI
                     KVYSDEFTFVLSFIANNCDYKTLLDCSEMIERVKPAHLLHYLEPIILDKSMVYCGGGM
                     VCSEEVKVHPYFEPIIKCSAVVNCGAGMLSREEIKVYPLSIKCIENNCKINIAIANDT
                     GVENVVVYPKSEVV"
     gene            complement(10814..11866)
                     /locus_tag="PC366_000927"
     CDS             complement(10814..11866)
                     /locus_tag="PC366_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDF2576466.1"
                     /translation="MYSDQTYEVIKNRTLENINLDIYKGEGSFLNNMVSGNNLELSKI
                     YLELSKIHKMAFIQDTYNQFLDKRVNEFGVYRKLGTESNGEVEFIGEKGTVINNGTII
                     SYRDLLFVVIKDVTIGSEEGDNSPVQALEVGKKYNLPTNCEFKLVDNISGVTKITNTR
                     SFEGGTDIETDEELKERFYKIQRNQATSGNKAHYEEWALEVDGVYNVKVYPRWDGPGT
                     VKVLIFGENNQAVDTETIERCQQHIDEEKPIGPTITVVTPLPIEISISAVMKLEDGYT
                     LDNVKESFLESINTYFRDIRGEIIYTKVMGILINTTGVHDLSNLLINGSTDNITINED
                     KIPSVTTVNFSEVENQ"
     gene            complement(11859..12287)
                     /locus_tag="PC366_000928"
     CDS             complement(11859..12287)
                     /locus_tag="PC366_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HDF2576467.1"
                     /translation="MSTIFPFIGVPEDYILPKTEELPIFREVAWDFEKDEPILEKGDF
                     KIIEKKEALKVWIYKCIKTNRYEHEIYSLEYGTELSELIGQKYTKGLTESEASRFIKE
                     ALLINPYILEVNVKSANFNRDVLSANVKVSTIYGEVEINV"
     gene            complement(12287..12613)
                     /locus_tag="PC366_000929"
     CDS             complement(12287..12613)
                     /locus_tag="PC366_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HDF2576468.1"
                     /translation="MANPINEFIGIIREEGKYHNQPSFFIGKIKSKLPDLKIETNNII
                     LEKEDILIDSWMIDRQLETFDTETNQEHQHEVKNPFIDNFESGDMVIMFRIGEKFAVV
                     SKLVSL"
     gene            complement(12629..14158)
                     /locus_tag="PC366_000930"
     CDS             complement(12629..14158)
                     /locus_tag="PC366_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2576469.1"
                     /translation="MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAK
                     QVFAENRLSVGTIAKTNVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFN
                     VIEKGTVTLSVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVN
                     VIMQKVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFY
                     IDTDKHTWQNGEYQIELELNFQNLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTA
                     YCPRKEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVI
                     TGVSGRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNV
                     SDKAKIVISEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGK
                     KVEQKNLQAGDLVFFHNPVSHVGLYIGNGEFLHAPQKGDVVKISKLSSRRDFNTARRV
                     L"
     gene            complement(14440..14862)
                     /locus_tag="PC366_000931"
     CDS             complement(14440..14862)
                     /locus_tag="PC366_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576470.1"
                     /translation="MEMWLRQAEDRFRFPVFPSSFSINGKAAVNSSSILKIGEVATFG
                     GVALKSISISSFFPNKDYTFCDYTGFPSPYDCVNKIEKWMKEGFILRFTITETNINME
                     VIIEGFSYEERDGTRDVYFTLDLKEYKRIKIPKVTPKQ"
     gene            complement(14862..17315)
                     /locus_tag="PC366_000932"
     CDS             complement(14862..17315)
                     /locus_tag="PC366_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576471.1"
                     /translation="MGNVREEGINMYLTDNYTPKMNQIISVTDNFRRATVAVSLSTNV
                     MASSIKNSIGSASSRVNSLNSSLRKVQTTASSVSSTMAKLSSSINAVSGVIGSLNGSI
                     MRLAITIAMIIDYFNKLIQKKNEFNSNIMIILIFKAKSDEVEKTKNKLLGNLKKIGGK
                     IWNIVIKAKDMTKRVISSILGKLKRVEKRPYQGSINLKDMVSSAMARILPKLMLFKNT
                     FWSGVIAIKDMASSIISKVFPKLRLFAGKVWSGAIAVKDMASGILGSIKGKISDLTNG
                     ATIGVAVKKGVDLLGQEQNQKVVLESVMKRNTGKTSQKDVDKYYDSLVNMANDTPFDP
                     EDVVAMGTKAKMISNITGGKKEKDITQAMVDVRALNMNTSSEQDVSAAFLSAAKGNME
                     SLNTLVGENYKTFDEALEGISVKQMGLAKEMSNTIPGIISGAQTSINNGLKSIVKPFD
                     DILGQGLKKIKTFIESGLGNLAGLSEKMAGKIGNVMNGKIIIGNKYDQMQSRSVKNGK
                     EFSDSTQYRISNEAEKRKMMVENKQERFENHAATMIGNAPKAIVNAGSTLLQNIDFTA
                     LIDSLLPVVNLVNNLLDSINNKSPIAQGLISIFGTIVTTAFQLIGPVVEAVSPIITRI
                     FTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIEPILGAFFNILDKVCKIV
                     KDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAGTKAGDSGKAYSSKKGNN
                     AFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNINIAKLADTIVIREEADIE
                     KITSKLVASIQLAQLGGVL"
     gene            complement(17315..17482)
                     /locus_tag="PC366_000933"
     CDS             complement(17315..17482)
                     /locus_tag="PC366_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576472.1"
                     /translation="MYYYWKKKGIRPSLFYAMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGM"
     gene            complement(17509..17955)
                     /locus_tag="PC366_000934"
     CDS             complement(17509..17955)
                     /locus_tag="PC366_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2576473.1"
                     /translation="MNENGLSKNINIVDLLLNADTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            complement(18069..18497)
                     /locus_tag="PC366_000935"
     CDS             complement(18069..18497)
                     /locus_tag="PC366_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HDF2576474.1"
                     /translation="MANMEARNVMSGTWGELWLDGNKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYMGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            complement(18511..19575)
                     /locus_tag="PC366_000936"
     CDS             complement(18511..19575)
                     /locus_tag="PC366_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HDF2576475.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAVLGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESRVNKGELILIKEAGAIR
                     IARGVNSLTELTEEKGEMFQKIKIVDTLDIIHSDIRKVIIDDYIGKVTNSYDNKCLLI
                     VAIKSYLEELEKSALIESDSTVEIDFEAQKSYLKSKGVDLSYMTLQEIKEANTGSKVF
                     LKAKIKVLDAMEDIDLSIEI"
     gene            complement(19580..20023)
                     /locus_tag="PC366_000937"
     CDS             complement(19580..20023)
                     /locus_tag="PC366_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576476.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEGSCFFVSILS
                     VICTPIMLNTNNKDIVISIKYLPKPQSKSIRMYEISDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYVLNFTITLNYLDSVYEEDVVYENMEEINLNLGE"
     gene            complement(20272..20712)
                     /locus_tag="PC366_000938"
     CDS             complement(20272..20712)
                     /locus_tag="PC366_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576477.1"
                     /translation="MENKKDILFKETDERLHNYKYLDIKIKNINLDIKRCENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKMEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIFKLSEIL"
     gene            complement(20817..21014)
                     /locus_tag="PC366_000939"
     CDS             complement(20817..21014)
                     /locus_tag="PC366_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2576478.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQL"
     gene            21183..21503
                     /locus_tag="PC366_000940"
     CDS             21183..21503
                     /locus_tag="PC366_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF2576479.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFNVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            21585..22091
                     /locus_tag="PC366_000941"
     CDS             21585..22091
                     /locus_tag="PC366_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576480.1"
                     /translation="MNNLDKLFELASQEEIIIHYTTYIAGDLEGLYINKHGIKIISLL
                     SNLKQNSKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIINIINSGITCVYEMADILNVDITFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            22792..23547
                     /locus_tag="PC366_000942"
     CDS             22792..23547
                     /locus_tag="PC366_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2576481.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(23690..24118)
                     /locus_tag="PC366_000943"
     CDS             complement(23690..24118)
                     /locus_tag="PC366_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDF2576482.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(24539..24739)
                     /locus_tag="PC366_000944"
     CDS             complement(24539..24739)
                     /locus_tag="PC366_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF2576483.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            complement(24922..26091)
                     /locus_tag="PC366_000945"
     CDS             complement(24922..26091)
                     /locus_tag="PC366_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HDF2576484.1"
                     /translation="MGGVALKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNM
                     EEKVMESANVEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYE
                     NEVKKMKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQK
                     DKENAFRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSEDIRNYIGQQDGV
                     ELQLTDEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGR
                     FKKNSIWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFV
                     GYEKKGRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            26327..27148
                     /locus_tag="PC366_000946"
     CDS             26327..27148
                     /locus_tag="PC366_000946"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HDF2576485.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVNFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRQEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIYIAKSVSDLGPSKVVITGILEDDNILNLAYDRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            complement(27224..28612)
                     /locus_tag="PC366_000947"
     CDS             complement(27224..28612)
                     /locus_tag="PC366_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase"
                     /protein_id="HDF2576486.1"
                     /translation="MLRSKKSNNKKVEKLRTIFIKYLSLFFVMTISFALLLMLSFSVL
                     LSSGVILPANYSEKQFDKYKEKIISSEKAIEDIIPNLYEYGVYTLDGNLISGTFNKKE
                     SKQVWNLMRDIEERHAYSESYIKFFKKDEVFIIKYKLVSEYSSPVLRAYLPKPEMLGM
                     IIFSIIFFIEIVILSKVFGKKFNIEMELLKNTTEKIEQQDLDFVVESSKIYEINNILF
                     SMDKMKLALKNSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPELL
                     EYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAINMSEFIKDVLLQIEALASTKN
                     LDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVSNKYLKFVV
                     TDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGILYIENSVKT
                     GGAMVTIEIPIV"
     gene            complement(28756..29514)
                     /locus_tag="PC366_000948"
     CDS             complement(28756..29514)
                     /locus_tag="PC366_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HDF2576487.1"
                     /translation="MRQLIRIFCSDLIKLKRNFIILMHICIALMGMGLFLWYYKVSGA
                     DNILKIVAYLQVIAIAFPLLSGVVCSMFVEQEYYAGNYKHMLTTSNPKYLTLISKYII
                     LVCLGFVATLVSVLGFKFGISKAYFTSSFYMISILILIGCNLFEYILHLFLSLRFGKG
                     TSIGVGIVEMLLSALLLTGLGSGIWQYFPCAWGVRFITIWSSFSSSKTVEYIKVESIK
                     AYQSTGLMCGFVTILAFVILCIWFSKWEGKKSEE"
     gene            complement(29516..30232)
                     /locus_tag="PC366_000949"
     CDS             complement(29516..30232)
                     /locus_tag="PC366_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HDF2576488.1"
                     /translation="MERFIRVEFQKMKGTFGMKLIWIVPVFCILLCGLGGGQNAAFNW
                     WYTTFLPGALTLISSLIVLKDEKSKYRGILPLPIEMKDVWAGKMIYCIICCSIASIIS
                     AIGVVFVGIIYKETISIGQNIIATILIILLFMWQIPLCMFLASKFGIFVTVLTNMFFT
                     IVGVAVFSTTEMWYVFPYSIPSRLMVVVLHILPNGLPVPEGSELLNNAVILPGVLISV
                     ILFVLFALVTRAWFNNREVK"
     gene            complement(30234..30941)
                     /locus_tag="PC366_000950"
     CDS             complement(30234..30941)
                     /locus_tag="PC366_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF2576489.1"
                     /translation="MNNYILQVKGVSKKFKEQMAVDNISLAIKSNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLETVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRKLIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVIGYQGEVSKEQN
                     LEKLFMKVVAENRKRGE"
     gene            complement(31058..31594)
                     /locus_tag="PC366_000951"
     CDS             complement(31058..31594)
                     /locus_tag="PC366_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2576490.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDED
                     AKEETTSKMINSKKTTKIPIEIISKDEKIVKYLQIDEESSLKDKLRLILDTLSNEYFN
                     GLDMEVEVKEKDNLVKINLIEPDKKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            complement(31696..32766)
                     /locus_tag="PC366_000952"
     CDS             complement(31696..32766)
                     /locus_tag="PC366_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HDF2576491.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAEFKK
                     ENKLYQEKVNIDKLDISVDNINVTIKKSSSEDVRVTTRGNNEFYKYNVTLKDKTLVVK
                     GERKYENKIKKIKNFDQLLNTSINSMFSHDYREIIIYVPNNVDINASSTSSYLFVYDN
                     VASNTITYKTSYGGFSRAITENKVNRLENLNLISNSNLHLSTKSILGVKNVNIESESL
                     DISSENEDVFINNIEEYIPENVNIKEKIGRNSNYESEFYLYSNMPIAKFLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEAIEEFNNDEEYDNDSYDYEHSEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNSLEL"
     gene            complement(32759..33817)
                     /locus_tag="PC366_000953"
     CDS             complement(32759..33817)
                     /locus_tag="PC366_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HDF2576492.1"
                     /translation="MNLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIIASLGSPKSIAKELILQTKEKNIEEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMNTDILNGKFSRFKSNIKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSVTIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGLEILAWQILLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINEDSYNNDYYNREEESIKETDEYNDDSINFEA
                     IYKDLEDIENKKGEDKHE"
     gene            complement(33804..34136)
                     /locus_tag="PC366_000954"
     CDS             complement(33804..34136)
                     /locus_tag="PC366_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF2576493.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DEGGNELE"
     gene            34335..35456
                     /locus_tag="PC366_000955"
     CDS             34335..35456
                     /locus_tag="PC366_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosyldiacylglycerol synthase"
                     /protein_id="HDF2576494.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKECIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDLSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKELCCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSNSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYKLVS
                     NEFDSIINFMKKNLEEFKTVIHPEKIADYISELIDNHYS"
     gene            complement(35584..37482)
                     /locus_tag="PC366_000956"
     CDS             complement(35584..37482)
                     /locus_tag="PC366_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HDF2576495.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLEDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVNPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEAGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAIENKDYQTASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
     gene            37797..38573
                     /locus_tag="PC366_000957"
     CDS             37797..38573
                     /locus_tag="PC366_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HDF2576496.1"
                     /translation="MEYIIFDLEFNQGFDKKLNKTVSNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKDIHPFISRMTNIKNSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGVGDLKELYRNINYHKLPSSSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMGKTNQFTLENVKQRKNK"
     gene            complement(38665..39417)
                     /gene="xth"
                     /locus_tag="PC366_000958"
     CDS             complement(38665..39417)
                     /gene="xth"
                     /locus_tag="PC366_000958"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HDF2576497.1"
                     /translation="MKFISWNVNGIRACVGKGFLDFFKEVDADIFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLVSADIHTEILGSDHCPVELEIK"
     gene            complement(39578..40528)
                     /gene="galT"
                     /locus_tag="PC366_000959"
     CDS             complement(39578..40528)
                     /gene="galT"
                     /locus_tag="PC366_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HDF2576498.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDEEC
                     PFCKGNEAHATDALFEIESEEGWLVKSVYNKFPIIDDMARDVYGVHEVMIESDKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLDRRVVYNGEAFLVLIPYATKYSGE
                     VRIIFKDKIEFGELNDNNIQELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEDLTKKLKID"
     gene            40913..42109
                     /locus_tag="PC366_000960"
     CDS             40913..42109
                     /locus_tag="PC366_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2576499.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYDMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            complement(42221..43567)
                     /locus_tag="PC366_000961"
     CDS             complement(42221..43567)
                     /locus_tag="PC366_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF2576500.1"
                     /translation="MTMKKRYNIAIVGGGSTWTPGLLKSLCKMSDRFPLNKVTMLDVV
                     EERQRLIGEFGKILFKEEYPKATLEYTTNPDEAFIDVDFVFVQMRTGGLKMRELDEKI
                     PLQFGLVGQETCGAGGFAYGLRSIGDMIEMVKTVRKYSPKAWILNYTNPAAIVAEALK
                     RVFPDDKRLLNMCDQPVNLLRSYGRLLDMDSRTFEPVYFGLNHFGWFTHLYDKNGEDL
                     VPKIKDLVANSGFQPVDAEQRDKSWLDTYGMVKDMLEDVPDYLPNTYVQYYLYPDKKV
                     AKSNINCTRAREVMNGREKRVFEECKSVIEKGTSIGSNLVHNDAHGEFIVEVAEAIAH
                     NKHQIAIVITENNGAINNLPDDAMVEVAAILTKNGPRPLHVGNIPTFYKGLLEGQLAY
                     EKLAVDAYFEQSYEKAILSLTLNRTIISPTKARQVLDALIKVNKDYWPTLYKENEK"
     gene            complement(43700..44452)
                     /locus_tag="PC366_000962"
     CDS             complement(43700..44452)
                     /locus_tag="PC366_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2576501.1"
                     /translation="MNLIDKLDINQKKLSTNEISLLNYFLKNSEKINQKKIKDIANET
                     FNSTAYIVRFCQKLGFSGYSEFKNFLVFSYSNRNERNKEFTKSQSDIFTDVMDTQNLI
                     NVENIDMCLNEIHNSKHIYFFGVGSSRLVCTEMSQRFSAIGVNVKYYDDSTLMYLAAS
                     NITKDDLVIAVSMSGETAQVIKACNIAKTNQVKVISLTNISVNSLSNIADIKLFVSSP
                     QYNFNSVNYTSRVPALSLMEYMFHKYIEKYNR"
     gene            complement(44611..46188)
                     /locus_tag="PC366_000963"
     CDS             complement(44611..46188)
                     /locus_tag="PC366_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2576502.1"
                     /translation="MKQKMKEFFLQLGKSFLLPIALISAAGIFLGISSAFSNPNIVSD
                     IPFLENNFIQGILGFTKAITGVLFGNLAIFFAISISVGLAKEEKAVSAFSGFVGYLVL
                     HTSVNYMLGCRGILAEPDMMREMGQAVTLGIQTLELGVFGGIVVGIITASLHNKYYNI
                     KLPDYLGFFGGTRFVPIITTVVFSILGIIIPYIWPYVNTIIQSVGIGIASLGYLGTFV
                     FGFLERLLIPFGLHHILNAMFRFTEVGGSLVVGGQEVFGALNIFLAQLSDPETISFST
                     EATRFLAQGKIPIMVFGLPAAAYAMYKTAKPENRSKVKGILLAGALATFVTGITEPLE
                     FSFLFVSPILFVIHAFLSGISFMMMHIFGVAIGNTQGGIIDLVVFGVMQPNTKWIYSI
                     ILGLVYALVYYNVFKVLILRFNLQTPGREEITDINFDLEPLSNKVEIAQSGETTKRAL
                     SIIKYLGGKENIEDITNCITRLRVVVKDMSKVDENAFKKYTGAMGVIKVSDKDIQIIY
                     GPSVSQVRDEVSFAMSI"
     gene            complement(46601..47053)
                     /locus_tag="PC366_000964"
     CDS             complement(46601..47053)
                     /locus_tag="PC366_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2576503.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            complement(47364..48809)
                     /locus_tag="PC366_000965"
     CDS             complement(47364..48809)
                     /locus_tag="PC366_000965"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HDF2576504.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWAQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYHSSYAVSGQTYTRKLDYQVISILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINKRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIMNDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            complement(48953..49861)
                     /locus_tag="PC366_000966"
     CDS             complement(48953..49861)
                     /locus_tag="PC366_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2576505.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKK"
     gene            50118..50942
                     /locus_tag="PC366_000967"
     CDS             50118..50942
                     /locus_tag="PC366_000967"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDF2576506.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILINEFIKLNF
                     SNTFINTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRVFFNSTVVAIALIVYGIIMIGLEKRNKRPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            50982..51512
                     /gene="lepB"
                     /locus_tag="PC366_000968"
     CDS             50982..51512
                     /gene="lepB"
                     /locus_tag="PC366_000968"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDF2576507.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSVVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRVIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKLFAMGDNRENSNDSRFPDVGMVDEDEILG
                     KVMVRLLPLDNIGKVD"
     gene            complement(51594..53375)
                     /locus_tag="PC366_000969"
     CDS             complement(51594..53375)
                     /locus_tag="PC366_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HDF2576508.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINEDVKVVPKVTPFKGIN
                     TDLLYVKDGRILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLEEYLNDENDEINLNLFLLDIC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEDVQIKDVVSIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLVIFTHTKQLCNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKTFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
BASE COUNT        17536 a         8836 c         5945 g        21238 t
ORIGIN      
        1 aatctttgta attgattaat ataaattaca atataatact atttttatct taatcttttt
       61 ctcttttaca gacaatcaaa aagcaatctt agtttatcga aataaattta tacaatctat
      121 tcatacaccc ctttacattt ttataacaat taaatctatt gttatatata caaatcaaaa
      181 taaaccatat attttcaact ataatatgtt aaaatcatat tatgagcata ttaatttaag
      241 caaaatgtca tttagacttt aatttagtag ttttatatta taaatttata tatttttaat
      301 ttcaaatgtc atttagacat tactcataaa aagaaaggag tgtattttgt ggatacttta
      361 ggaaaaagaa ttgcttattt gagaaactcc aaaaaactta ctcagcgcaa acttatggat
      421 attttaaaat ttgaaaactt aggcaagtat gaaacaggag atagaaaacc taattgtgat
      481 atactaatgt caatagctga ttattttaat gttacgactg actggcttct ctatggtaaa
      541 gagaaggtaa atgtcaatag tagtgtaaaa gaagataaag aagattactt acatgttact
      601 aatgatgaaa tgatgatatt aaatctatac agacaactaa acgaacgtga taaaataaaa
      661 atagaaggaa tacttgaact taagatatct gaatataaag acttaaaaaa gcattcctct
      721 aataataatg aagataaaat ggtttaaaca tacataattt gatacgattt tacatcatct
      781 attaaccttc tttttttgta gtatattact aaaatatgga tattggatta tttaaaaaca
      841 agtatagtct aatttcaagc acatttataa tatttagatt atcttatcca tattttagtt
      901 taagtacttt gaaaaatata atacatttct atgtataatt tatattccta agaaatgcat
      961 tactcatgtt tttaattctt ccaacatctt tctatacaca attgtacatc cttcataatt
     1021 cccctcttta agaaggattg aacatgtact agaatattta gttaaagtat ttaatctttc
     1081 catatttaag ctttttatat tactaagtgc tgtaataaaa tcatcaattg ctctacaaca
     1141 ctctataacc ccatctgaat ccaatttgca cacaagaata ttcacctact ttatatacta
     1201 tttattaatc atcttctgaa tattctatat taagtaattg ataaattgat gatttatatt
     1261 ttttacctgt tcttcttcca tttaaaatag ctgacaaata gttttcatta acacctattt
     1321 tcttcgctaa ttccctttga gtcatattta attcaataag tctttgcttg acttgcactc
     1381 ccaaaaaagg tatccatttt tttcgagcat ccatttatca acttcctttc taagtgattt
     1441 atatttactt ttatattact ttagcttacg caccccctct atttagtata tatttttaat
     1501 atgtacacat attaagtata taaatttatt taatactaaa taagattttt tgattacttt
     1561 gtgctaaaat taggatgtaa attcgtatca ttaagttaat tataaagtca ttttgacctt
     1621 aagtcaatgg tttttatgtc attttgacct ttaatttgaa actatttaca tcttaaaaag
     1681 tctttttgac attaattgaa tggagagtgt ttatggatac tttaggagaa agaattgttt
     1741 atttgagaaa agcaaaaaac cttaaacaat atgaactaga agaaatgtta ggctgtgaca
     1801 acttaagtaa atttgagaga aacattagaa aaccaaatta tgaaatatta aaatctatag
     1861 ctgagatatt taatgtttca gtagactggc tattaaatgg agataatcta tcacataaat
     1921 cagatttaat ttgcgattcc tcctcaaact atccacttaa tagcataaac tctaatgaaa
     1981 taaagctttt aaacaacttt agaaagttaa atgattatga taaagccaaa atagaaggta
     2041 tgattgaatt aaaacttcat gaatatgaaa aagagaagga tttaggaaaa attgagtata
     2101 acaaaaataa agatgagaaa atagataaat aatttttatg ttgcttttga tacgatttta
     2161 catcatttct ttgttctaat atttttattt catttatttt cttttttata attttatgat
     2221 aaaataatta gtatattttg ctttacttga atgtaattat ttatacaaaa gtcaaacata
     2281 atataaatgt agtaaatttt tagtttcaag taatatctcg ttattataac taaatattta
     2341 ttaaaattag gaggataaaa tgggcttaag agacaaattc gcgcaatcat ttgctagatc
     2401 aaaaactatg agtggccctg agaaaaaggc taatgaaata atgggtaaat tgcttcttaa
     2461 gaaagctata ttacctatcg ttttaatgtt cgtgataata atcgctggag ctatgcttaa
     2521 aatcaattct tgggttacac ttggcataaa tttagttatt gctgttggtg ctttcttcta
     2581 cataagaaat tctagtaaaa agtatcagaa ctttaaacct tatgttggca atttgattag
     2641 tttagagaaa aaaggtaaaa aagagtacgt tgctattata aaacaaggta agttaccagt
     2701 taagttacaa atagcttatg gtggtgaaga ccttgaacat gttaagaaaa atcaaatggt
     2761 tcagataagt tataatccag atgctaaaat agctattttg gttaatagac aataatttaa
     2821 taaaaaaaag gagttgtctt aaaattgatt ttttctaatc aaatttaagc ttaactcctt
     2881 tttgaatttt tatatgttat ttttatatat tatttttatt acttttttta attaatattt
     2941 taaaatataa aatccttctc aataaaatag ggcactatct acaatactac tttatctttt
     3001 cctaataata tataatctgg tgctactgct actttcatgt tatacaccgt tttgtaacat
     3061 accttttata tcagtaacat cttccttaat ttcctctaca tctgttttca ttattcccat
     3121 ttgaacaagt atatttttgt ttatttcttg ttgttgtgta gataattcta taaaattttc
     3181 tacagttttt ttatacatgt ctctatcttc ttttttctcc tgcatagtat ttttaaataa
     3241 tagagcacat agtataccta ttgcccccag actactcaat tcggttatta atttatccat
     3301 tatagcctcc tattgtctaa attttttata cttatagctt taatttttgt tatattctta
     3361 catcatgcaa tattatattt tcaggattat caatttaatc ttctgtactt taaattgtag
     3421 gtttaattta tagattgaat aaataataaa tatatataca atttctaata taacaaaaaa
     3481 taagtacaag gcttacttat taaagttaag accttgtact ttacataaaa aaaataacta
     3541 atacatagtt attctaaatt tactattcaa ctggtatttc taattcttta catctaattc
     3601 taacttgctc tctaattact gctggtactt cttctattgt ttttctgcct cttaaaatta
     3661 aagctacata tacttctacc attccactct cacctccaga ttttcttaca ctaaaagtgc
     3721 ttatattact tgcttcattg acagaacttt gacttaacaa catctcatat atttctgcat
     3781 ttgctataaa attatttgtt atatcatcat cttgctttgc ttgacctata cttatgtctg
     3841 aaatgtcttt atactgcatt tctacttttc taccttgttt gatttgttct attttatttt
     3901 tatcgaattt aaacaatttt tacacctcca ttttaagctt gtggctcgtt gttttcagca
     3961 tcatatctaa aaatcataga tggacgtttt atagctgtcc atttatctcc tttttctact
     4021 atgattttag gctgagcact ttttatgttg gcttcttcta attcatagat ttcttgataa
     4081 cttgagtctg attttttgat ttcaactagt ttcatgtctt tgaataagtc agatttattt
     4141 atttttactt gaactttagt tttatttatt aattgatata tagggtctcc aagatttaaa
     4201 tcttcttcaa gtcctctatc tagtgtaatt gtaatatctt gttcattaga tgttgtatta
     4261 actaccttgt acattctatt acctatcata acataagaat ctttaattat agaatttcca
     4321 gtactctctt taaaaataaa taaagatgca tataaatcat cacctttaca ataagctcta
     4381 aatagtatct tattctctcc tattttaatt ttatctggtg gtacttcaaa ggatattttt
     4441 tcagtagtta aatcacttac agattttaca ctttcaccat ttataagcat ttctattcta
     4501 cttatatctt tattagggtc ttgtattttt atcttaattg atgaaattga tttttcagta
     4561 atttctatag cagcatttgt cgttcctact tctgatataa tatataatgt attgtctgtt
     4621 gcaagtacat cctttactgt atttacatct tcagaaatag gtactatagt aaattctttt
     4681 aaaaattcta ctggttgttc aattttatat acatccctat tttttccagt aacccatact
     4741 gaattatcat ttttaagtac taatatatgg tcacttccat aagattttat ttctcttatg
     4801 tctgttagtg cttttgtaaa gaacttaatt atagtatttt cactatcgct tcctaatcct
     4861 aaagctccct tatcattata tccttgtaca aataattcat tacctgtagt tactactaat
     4921 gtatagtttt taccacaatg tacttcttta cagctagata tagttgtaat tctttgtaat
     4981 tcagtaactg gattattgtg acctatacct aattgatatt cggaattttt accaatagac
     5041 caaagactat catcagattt tataaaataa gtaaagttat ctccacatga aacatgcttt
     5101 acatctgata cattaatctg cacaaattca tccacttgat ttatagacaa gtcttgcaat
     5161 aattctccat ggtagtttgt accacatcca tacattgttc catcattaag taatataata
     5221 atatgagtct tagaaataga tacttctttt atatcttcat atggaagctc agtataaagg
     5281 tctcctttgt ataaatttcc taatactaaa ccataatcta tgtcttttgt ggtaggtatc
     5341 actatcttat tgtttagaag tataaagtta tgtctgtttt taatagatgt caaatcaccc
     5401 attacaaaat tcatatgctt ataattaaat attctattat cattatttct actatcgtat
     5461 ctatttccaa cacctaattg tccatagtta tttaatccac aaatatatat atcattagta
     5521 tcttttattg ctatatttgc atattctaaa ggaagtattt tctttactct tgtattggtt
     5581 tttataaatg tatctctttt tgttacatca ccaacaccta attgtccatt attattaaaa
     5641 cctgtaccat ataggtctcc attatcactt acataatgtc cacatctata attcattcca
     5701 atatcctttg cctttgatgc tattttttta atcttctctg gagtctcact tcctgtacct
     5761 gaaccattac tacatttgcc tgcagtatat acatcccctt cacttgtaag taaaagtact
     5821 gcattatttc tgtttggagc tacttttact acatttgaaa ttggaatttc agaaaatgaa
     5881 ctttgattgc tattactatt tagacctaag caataatcag tatttaaacc tgtactatat
     5941 gcagtattat agattgttat tatataggta tttatttcat ttggtataac ttcttttaca
     6001 ttttccatac actttataaa actatactgg tcagtagtat ttcccatacc tagttgtgaa
     6061 ttattattgt atccacaaca atatgcaatg tttgtgtcct ttacaataaa tgttgttgta
     6121 tctgagcagt acacatctct tacattagtt atattgttta cagtaaatgt caatacgtct
     6181 ggatggttgc tttcgcttcc taagcccagt tgcccatgag tgttttctcc acatgaatat
     6241 aatgtgttat catctttgat tgcatgcgag tgagtagtcc ctaaaacaac atctcttaca
     6301 ttttggatgt ttactttggt aaatgtattt ctatttacta tatcacctaa tcccagttgt
     6361 cctttggtat ttaatcctgt ggagtatagt gttccatcat ttctaattgc aaatgttgtg
     6421 ttaccatcta tacttgttga tattttcttt atattatcaa ggtttatctg agtgaactta
     6481 tttctattta ttgtgtcacc taatcctaat tgtccagaac tattatttcc tgtggcatag
     6541 gctgttccat cattttttac tataaacatt gtatttcttg atgttgtaat ttcttttata
     6601 tcatccataa atataaatga gtttgattgt tcagttatat ttgtgaattt ttttactggt
     6661 tcgttgttat attcccctat cccaagtttg ttattctgat tcattcctgt tacatatata
     6721 ttgttatttt tatctactac tactacagta tttcctttta caattatatc ttttatgtct
     6781 tttaatcctg tatcatagtt acttgtgcca tctatatttg ttgaattccc aaattgccca
     6841 ctattagcaa tcccttttcc atataacttg gaattactat gatatattat aaaattactt
     6901 cctaaattag aactctcaga attaatacta gtataacttc tatgtccagt aatggttgag
     6961 ccaaatgttt ttggatatcc agtaatatat gaacttcctt tcttaaaaaa taatatatta
     7021 tttgacatcc ctattacttt ttcaattcca ctaaaatcag tctcttgtat aaaataagta
     7081 ttatgatttg aatttgtagc ctcaataaaa gttccatatc ttgaataatc agatatactt
     7141 ggactgctat ttaatgttct taaatatcca tgatatcctg ttaaataaac ataacctcct
     7201 tcgtcaatta ttgcacaacc atcataaaaa ggaaaaacat tagttatttt aggtaacgtt
     7261 ctaagtccat ttgatgtaga agatgttgaa tttgttctac attgagatac taatgctttg
     7321 ctttggttac tattatttcc tttacctaat tgataattat aattgtatcc agaaacatat
     7381 agtttccctt cactgtttat catatataca gaataatcat atgctgctat cttttcaata
     7441 ttacttattc cctgcttata tggataatta gaagtttttt ctatattatt ataaggatta
     7501 tttccccatc catatacttc ttttgagtga tttaaagcta tgacataatt gcttcctaca
     7561 caaaaatcct ttacattctc tatttctatt tttgtaaata tatttctatt aacttcatct
     7621 cttaaaccca attgtccatt actatttaaa ccacatgaat ataatgttcc attattctta
     7681 agcacaaaag ttgagtttcc gtttcctttt atatccaaaa cattatctat atccacctta
     7741 gtcataactg acctgttaac agtatctccc aatcctaact gtccataatt atttaaacca
     7801 caagcataca atgtaccatc attcataaca ataaacatat tgctatctgt taactctatc
     7861 ttcttataat cttgaaaatt atcacttaac tttacattta aaaattcact attgtccttt
     7921 gtaacatata aataatcatc attaaccaat aaacctgaat aattatctaa atttgaagat
     7981 tgcacatttg aaaactcata cagaaaagtt gtatgaaaaa atgaaccaag ttgacctgct
     8041 aaattacagc cagatacaaa tatctctttt gaaccattta ttaaaaaatt aaattgagaa
     8101 ccacatttaa tatcttttat attttctaca ttaaccttag caaaagtatt tcttgatgct
     8161 acatctttat tggcattggc tagttgacca taattgtttt gtcctgtact aaacagtgta
     8221 ttatcgtatt ttaatatcat agtatgatta tttccacaag aagcatactt aacattattt
     8281 atactagaaa gagtaaatac aattgaatta ttattatttc ctgtaccaag ctgaccaact
     8341 ccattatagc ctgtagtata catagttcca tcattcttaa taagaattgt atgactacta
     8401 ccacacgcta tctgttttac attatccata ccttctattt tattaaatac acttttattt
     8461 aaagtactat taattcccaa ctgcccattt gaatttaatc cacatgcatg tgctgtccca
     8521 tccattttta tgataaatac agattgatta taagtcacta catctttcac actatctata
     8581 tttactttag taaaagtagc tctattgtta gtatcaccta gtccaagttg accacttgag
     8641 tttaaacctg ctgaatataa tgttccatca tttttaagca caaatgtaaa gtcataacca
     8701 catgcaacag tttttacatc atctattggt agcttagtaa attcataata tactgtagac
     8761 tcaattacac ctaattgacc tacattactt gttcctgctc catatgcaaa tccatcttta
     8821 gttactgcta cactgtgttt tgaaccacaa gatacatatt ttacattatc aatttttact
     8881 ttactaaaca tccttctctc tgacgaatct tttccaagtc ctagttgaaa acctgtatta
     8941 tcgccacaag catataaatt accatctgat tttaaaccaa aggtactatt acttatacca
     9001 gtaaaaaatt ctacaaaatc ataatcatta tatcttttat caaaatcatc aatcaatatg
     9061 ttcttatcat taaaataagc accacgctgt aaaagtttat tttgcttcat tattagtact
     9121 acctccttta tttatcttat ttcatatgaa tatttactta gagttatatc tttttgttct
     9181 tttaaataag tgttactaga ttttgtctca acaaagttat tatccatatc atgtatatat
     9241 ctaactctat ttgcactaaa tggtaatact acatctctaa aaatcacatt accaatttca
     9301 cctgttatac attttctatt taaatctaac ttaagccctt ctatagctac tatgttattt
     9361 ccatttgcta atgtatcata ccaataacca gcctcatcta cagttacttc tgactctaat
     9421 tctaggtata ttaatatatc tagcactttt tcagataatt tgttatagct attttttaat
     9481 actgatatat cagtttgtat ttgaccactt ataacatcat caaaagatat attttctatt
     9541 tttttaacta cctcatttat agctcctgat aaatctttag aatctgtagt taatatatct
     9601 gtatctccaa tttttacttt tatttctttt atatttttat caaacttatc atctaaatct
     9661 tgaatatcct tttgagttac aaaaaccaac gtcgggtcta cttctaatgt aacatttgaa
     9721 gtattggaca attgtaaaat catttttaca accaaatctt taatactgcc atcttcagca
     9781 cgtggcttat acgtctctgg atacttacct atagctatta tattattctc attatccaga
     9841 acagcagctt ctcttatcat aaatccacca actgttcctg gtaaaatagt ctctataact
     9901 atccaattag gatttttttc atcaattctt agagaattta tatttccttc ccaaactaca
     9961 ttctttaaag cagtttgttc ctctgttggc tcataatatt ctccattact atctccaact
    10021 tgaaacttgg ttaatccaac aagctctcct agtgcagttg catttgctat tttttctcta
    10081 ccaattttgg ttaatattat ataaaatttt tcttccaatt ataccacctc cgatttagga
    10141 taaactacta cattttctac gcctgtatca tttgcaatag ctatattaat cttacaatta
    10201 ttttcaatgc atttaatgct taaaggataa acctttattt cttctctact taacattcca
    10261 gctccacagt ttacaacagc actacatttt ataattggtt caaagtatgg atgaactttt
    10321 acctcttcac tacataccat acctccacca caatagacca tacttttatc tagtattatt
    10381 ggttctaaat agtgtaataa gtgagcaggt tttactcttt caatcatctc gctacaatct
    10441 aaaagagttt tatagtcaca gttatttgct ataaaactca atacgaatgt aaattcatca
    10501 ctataaactt ttatatctgt ttctgatttt gtatatgcct cacatatact ttttataact
    10561 tcaatagtac tagtacctct gcttctcatt ttagctttta tattgctacg tcttgtgtca
    10621 aaatcaagtt cttttttttc aatgcagagt atgtcttccc acatatctaa tccccatgtc
    10681 gctgtatcaa caaataattg gttaaaggta tcatcaatat cttctttaag aatatttaat
    10741 tctgtatcgt atgcaccttg tatctcctct acaatgtaat ttctatcaaa tgatggtagt
    10801 ttatcaatta gcttcattga ttttccacct cactaaaatt aacagttgtt acactaggta
    10861 ttttatcttc attaatagtt atattatctg tacttccatt tataagtaga ttacttaaat
    10921 cgtgtacacc agtagtattt ataagtattc ccatgacttt tgtatagatt atctctcctc
    10981 taatatctct aaagtatgta tttatacttt ctaggaaaga ttcttttaca ttgtctaatg
    11041 tatatccatc ttctagtttc attactgcac ttatacttat ttctattggt aatggtgtca
    11101 caactgttat agttggtcca ataggcttct cttcatctat atgttgctga cacctttcaa
    11161 tcgtttctgt atcaacagct tgattatttt ccccaaatat caagacctta actgttcctg
    11221 gaccatccca tcttggataa accttaacat tatagactcc atctacttcc aaagcccatt
    11281 cttcatagtg agctttattt ccacttgtag cttgatttct ttggatttta taaaatcttt
    11341 cttttagttc ttcatctgtc tctatatctg taccaccttc aaaacttctt gtgttagtaa
    11401 tctttgttac tccagatata ttatcaacta gtttaaattc acaatttgta ggtaaattat
    11461 atttcttacc aacttccaga gcttgaactg ggctattgtc accttcttca ctaccaatag
    11521 ttacatcttt tattactaca aatagtaaat ctctatatga tattattgtg ccattattta
    11581 ttacagttcc tttctctcca ataaattcaa cttctccatt tgactctgta cctaactttc
    11641 tatatacacc aaattcattg actcttttat caagaaactg gttatatgtg tcttgtataa
    11701 aagccatttt atgtatcttt gaaagttcta gatatatctt cgaaagttct agattatttc
    11761 cagataccat gttgtttaga aaagaacctt ctcctttata aatatcaaga ttaatatttt
    11821 caagagttct attttttatt acttcatatg tctggtcact atacatttat ttccacctcc
    11881 ccatagatag tggatacttt tacatttgca ctcaatacgt ctctgttaaa gttagcactt
    11941 tttacgttta cttctaatat atatggattt attagaaggg cctcttttat gaatctacta
    12001 gcttcacttt ctgtaagacc ttttgtatat ttttgtccta ttagttctga aagctctgtc
    12061 ccatattcta aagagtatat ctcatgttca tatctatttg tctttataca cttgtatatc
    12121 caaactttta aggcttcttt tttttcaatt attttaaagt cacctttttc taaaataggt
    12181 tcatcttttt caaaatccca tgccacttca cgaaagattg gcaattcttc tgttttaggt
    12241 aagatataat cctctgggac acctataaaa ggaaatattg tactcattat aagctcacca
    12301 acttacttac aacagcaaat ttttcgccta ttctaaacat tattaccata tccccagatt
    12361 caaagttatc tataaaagga ttttttactt catgctggtg ttcttgattt gtttctgtgt
    12421 caaatgtttc tagctgtcta tcaatcatcc aactatctat caaaatatct tctttttcta
    12481 atatgatgtt atttgtctct atttttaaat ctggtaattt acttttaatt tttccaataa
    12541 aaaaagaagg ttgattatga tactttcctt cttctcttat tattcctata aattcattta
    12601 ttggattagc cattatatca ccatcctttt ataatactct cctagctgta ttaaaatctc
    12661 ttctactact taacttactt attttaacta catcaccttt ttgtggagca tgtaaaaatt
    12721 ctccattacc tatatataat ccaacatggc tgactggatt atgaaaaaat actaaatctc
    12781 ctgcttgaag atttttttgt tctactttct tgcctttttt agattgttga tttgacgttc
    12841 ttggcaaact aacattaact tttttaaaac agtagaccat taaaccagaa cagtcaaaac
    12901 tacttggtcc atttccaccc catttataag gtttacctag atgttttttt gcctctgata
    12961 ttactatttt agctttatca gatacattac cagaataacc accaataata atttttcctt
    13021 ttcttcttcc aaatttacta gcttcttcaa catttccaaa taaaatatct atatggtatg
    13081 ttccattttt ttctatagtt attgcaggtc ctacgtcatt tactttatag actccatcac
    13141 gaccagaaac tcctgtaatt acctgtattt catctccata gttcaataaa ggatgtttat
    13201 ttaaaaactc ttttgtataa taagtttgct catatttacc aaccatagga gcagcgcaag
    13261 tttttttaga tgggtcaagt tttttctttc tacaatctgt atctccacct tcttcttttc
    13321 taggacagta agctgtaaat tctgctgtaa actcttttcc tcctgcataa tcttctcccc
    13381 ctaaattact ttcttcctta ggttcatcct gtcctgctga cttttcatcc ataagatttt
    13441 gaaaattaag ttcaagctca atttgatatt ctccattttg ccaagtatgt ttgtctgtat
    13501 ctatataaaa tagtcctaca agctttgtat aagaatcttt aacttttact cctctaccag
    13561 ttatacaact tacatctcca taacctttaa gagaacagct tttttctatc ccattaaact
    13621 cgctatcaat atctacatct tgattttctt gttgctgaat tactttttgc attattacat
    13681 ttacttcctt aaaaatttca ttatctattt tttcgctaat cttgcttcca tactggtcta
    13741 ccactattac tttatttttt acattttcca tgctctccga aaaggtggta tttataatat
    13801 taaatccctc ttcaaacata acacttaatg taacagttcc tttttcaata acattaaact
    13861 tatctaaatt agcctctatc atatactttt tctttgtctt tttacttgcc tctgtatatg
    13921 cactcattat tgtgtcataa ccatttactc ctataaacat ctttgtatac ttgacattgg
    13981 tctttgctat tgttccaact gaaagcctat tttcagcaaa tacttgcttt gctatgtctt
    14041 caactaactt atctttaaaa ttgtatgaca cttcactttg tgtaagtaaa aatcccatat
    14101 ctttagatac aaaactaatt tcattactgc ttgaatcttt agacctatta attatcattc
    14161 ctctaaagag ttctttctca tctacataga aacagactgt actagctatt ggtatatcga
    14221 tttgttggaa atttacatca aatgatgatt gtattattga aaactctagt gtccttgatg
    14281 gagatttata atcacctgac catgatacct tgtctactat gtcagttatg tcatatatac
    14341 ttccgttttt tatgtgtacc caaatcttaa taataaaaaa tcacctgcct tttcatttaa
    14401 ttctatcagc agttacttac aacttattat ctataatagt tattgttttg gagttacttt
    14461 tggtatcttt attcttttat actcttttaa atctaatgta aaatatacat ctcgagtccc
    14521 atctctttct tcataactaa acccttcaat tatgacttcc atatttatat ttgtttccgt
    14581 aattgtaaat cttaatataa aaccttcctt catccatttt tctatcttat ttacacaatc
    14641 atatggtgat ggaaaacctg tatagtcaca gaaagtgtag tctttatttg gaaaaaaact
    14701 tgatattgaa atgcttttaa gagctacacc accaaaagtt gctacttcac ctattttgag
    14761 tatactagaa gagtttacag cagcttttcc attaatacta aaggaagatg gaaatactgg
    14821 aaatctaaat ctatcttctg cttgtctaag ccacatttcc attataagac accccctaac
    14881 tgtgccaatt ggatacttgc aactaatttt gatgttatct tttctatatc agcttcttct
    14941 ctaatcacta ttgtatcagc taacttagct atgtttatat ttccaccatt ttttctgctt
    15001 ctatattgat ttgcttcttg tttagttaaa accatttcac cttcatggag tctggtttga
    15061 tagtcattat aaggaacata gttcaatcca aatgcattat tacctttctt acttgaataa
    15121 gctttaccag aatcaccagc ctttgttcca gcatatggat tatctttgta atttttttta
    15181 ctcttttcca ctagatttaa aactgttcct gtgatgcttc cattttttat cttattaatc
    15241 atagtttgcc accatttgca tatatcttta actattttac atactttatc taatatgtta
    15301 aaaaaagctc ccaatattgg ctctataatt ttccatccag tttccaacag aggtcctaag
    15361 gtctcccata cagttttcca aataacaccc agtgtctcta taaaattgtt tatttgaggt
    15421 gcatattcac ctaaaaaagt aaaaattctt gtgataatag gactaacagc ttcaactaca
    15481 ggtccgatta gttggaatgc tgtagttact attgtaccaa atatacttat taatccttgt
    15541 gcaattggtg atttattgtt tatactatct agtaaattat ttactaagtt tactactgga
    15601 agtagtgaat ctattaatgc tgtaaaatca atattttgta atagtgtact tcctgcgtta
    15661 acaattgctt ttggtgcatt ccctatcatt gttgctgcat gattttcaaa acgttcttgc
    15721 ttattttcaa ccatcatttt acgcttttca gcctcattag aaattcgata ttgagtagaa
    15781 tcagaaaact cttttccatt ttttacactt ctagattgca tctggtcata tttgttgcca
    15841 ataattatct taccattcat tacattgcct attttaccag ccattttttc agataagcca
    15901 gctaaattcc ctaatccact ttctataaaa gtttttattt tctttagtcc ttgacctaaa
    15961 atatcatcaa aaggtttaac aatactcttc aaaccattgt taatgcttgt ttgagctcct
    16021 gatattatac ctggtattgt attactcatt tctttagcta accccatctg ctttacactt
    16081 atgccttcca atgcttcatc aaaagtttta taattttctc ctaccagagt attaagagat
    16141 tccatatttc cttttgctgc acttaagaaa gctgctgata catcttgttc actacttgta
    16201 ttcatattta aagctctaac atctaccata gcttgagtta tatctttttc ttttttgcca
    16261 ccagtaatat tactaatcat tttagcttta gttcccattg caacaacatc ttcagggtca
    16321 aaaggcgtat catttgccat atttactaaa ctgtcataat acttatcaac atctttttgg
    16381 ctagtttttc cagtatttct tttcattaca ctttctagaa caactttctg attttgttcc
    16441 tgaccaagta agtcaacacc ctttttcaca gcgacaccta tagtagcacc atttgtcaaa
    16501 tcagatatct tcccttttat cgaaccaagt attccacttg ccatatcctt tacagctatt
    16561 gcaccactcc ataccttacc tgcaaacaat ctcaatttgg gaaatacttt acttataatg
    16621 ctacttgcca tatcttttat agctattaca ccactccaaa aagtattttt aaacaacatt
    16681 aacttaggca aaattctagc catagcacta cttaccatat ctttaagatt aatacttcct
    16741 tgataaggac gtttctctac tcgttttaat tttcccaaga tactacttat cactctctta
    16801 gtcatatctt ttgcttttat tacgatattc caaatcttgc caccaatctt ttttaaattt
    16861 ccaagtaatt tatttttagt tttttctact tcatcacttt tagctttaaa tattaatata
    16921 atcataatat ttgaattaaa ctcatttttc ttttgaatca acttattaaa ataatcaata
    16981 atcatagcta tagttattgc tagtctcata atacttccat ttaaacttcc aataactcct
    17041 gaaacagcat ttatgctaga acttaatttt gccatagttg aacttacact actagcagta
    17101 gtttgaactt ttcttaacga ggaatttaaa ctgtttactc tactacttgc acttccaata
    17161 gaatttttta tgctactagc cattacatta gtggaaagtg aaacagccac agttgctctc
    17221 ctaaaattat cagttactga tataatttgg ttcatttttg gtgtgtaatt atctgtaaga
    17281 tacatattta taccttcttc tctcacattt cccattacat accacctcct gtcaaaggac
    17341 acactccata tccatgtttc attttttcaa cttcttcctc aatttctaag gcgaaaaaag
    17401 cttcaataag ctttaattcg cctttatcca ttgcataaaa aagggacggt cttatacctt
    17461 ttttcttcca ataatagtac attattgtag tcttggtatc cgtccctatt agttttttac
    17521 ctcttctatc actgcatttt taccataacc cataacatct tgaagtattc tatataggtt
    17581 ggtaatttca cctggtaata atagttttct tgccaattct tttggtgttg gagccttaaa
    17641 tttatccatt agttccttat ttttaaataa aagctttcca tccaaatcac aaacaccttc
    17701 tataattgta agcatctgca tctccggtaa gtctatatcc gttttcatat tttcatcaat
    17761 tttaagacaa gtattttgta tctcttcatc tttacttatt gttaaagctc tacacattac
    17821 tttaaattcc tgcccaaata tagttgataa tctcttaagt tcaactatag tacttggtct
    17881 ttctaagttt tctgtatctg catttaaaag taaatctact atgtttatat tttttgataa
    17941 tccattttca ttcattatta tttgctcctt tatcaatcaa attcaatcaa ctaacttttt
    18001 tacttattaa ctacctaaat ttattaagta tatatctact aaatatcagt ataaaaccaa
    18061 atataaaact aaattatatc aagaaaatca tactcagtaa atgtgaaagg tgcttctatc
    18121 tctcctttta ctccaacctc ccaatcagct aaagttaaat catcaaatgc tatatttttt
    18181 actgctattc tttctgctcc ataagaatct gggtcattta atttagatat agcaacaaat
    18241 ctaggttcag aacctctctt tatcttttct ccaattaact tgtgcattct tgaactaaca
    18301 tggtatagag ttattgaacc ttttccttta tatcccatat actttgtatc agtacccatt
    18361 tgacctgcta ttataatatc ctcttttgta aattccatct ttgcttgaaa cttctttact
    18421 tctgctactt tgtttccatc aagccaaagt tctccccaag taccactcat tacatttcta
    18481 gcttccatat ttgccatatt aataatcctc ctatatttct attgataaat ctatatcttc
    18541 catagcatca agtactttta tttttgcttt taaaaatact ttagaacctg tgttagcttc
    18601 ttttatttct tgtaatgtca tataagataa atctactcct tttgatttta aatacgattt
    18661 ttgtgcttca aaatctattt caacagtaga atcagattct ataagtgctg acttttctaa
    18721 ttcttctaaa taacttttta tagctactat caataaacat ttgttgtcat aactgttagt
    18781 aacctttcct atatagtcat ctattatcac ctttcttatg tcactatgta taatatctaa
    18841 agtgtcaact atttttattt tctggaacat ttctcctttt tcttctgtta actcagttaa
    18901 agaatttact cctcttgcaa ttcttatagc ccctgcttcc ttaataagta taagctctcc
    18961 tttattaacc cttgattctg catcaacttt cgtcatctta ggtatatcaa ctacatcact
    19021 aagcttagta taagttactg attgacttaa aggtgttcct gctataagtc cagccaccct
    19081 acttgtaaac tcatcaacac tgtatttctt ttctccaact aacacatctt ctgtagtaaa
    19141 attaattatc ccttcatgat ttcctacaac ttttcctaat acagctttaa ccttaacctt
    19201 atctatatct ctaagtttaa ttatccaatt ttttatagca gtcttatcag cttctactgc
    19261 ttttggcata catagataat taaattcctt agtctctaaa aaatctaatg cagtttgaat
    19321 atctgcttct ccttctatta cataaactaa taatttattt ggagtgttaa catttcccat
    19381 caaagctaaa tttatatact ctttattttc agcagataaa tcaactggta tatcctcttt
    19441 ttcatgtatt tcattaagac ctagtgcctt agcatcttta agcaccattg caattattcc
    19501 tctagctgaa cgttctttaa cagttgtagc tagctcctta aatgatatgt tgatacttgg
    19561 taatcctata gccatactat cactctccta aatttaaatt gatttcttcc atattttcat
    19621 atactacatc ttcttcatat acactatcca gataatttag tgtaattgta aagttcaata
    19681 cataaattga ctcttctttt ttaatacttt gttctagctt tgttatattt aattttctgt
    19741 ctgttacctt tatatttctg ttgaataact tatttaattc atctgaaatt tcatacattc
    19801 taatactctt tgactgtggt tttggtaagt attttataga gataacaata tctttattat
    19861 tcgtatttaa cattataggt gtacaaataa ctgatagtat acttacaaaa aaacaagacc
    19921 cttcagagcc ttgcacactt tcatcatcaa taaaaatact ttcagtaaag ttttttttga
    19981 gaatctcaat aattgtttct aatatttcct tgtatttaag caaataatca ccacactatc
    20041 actaaatatt cttgcttaat ctgataatct tactataaat gatataagtc atttttaaat
    20101 atacatctca tttattcctg tcaaatatct tctatatttt taggtaatat tattcttttc
    20161 aatttatcac ctccttcaat atggatttct ttcacaataa cattatctca catattttat
    20221 tgcctagtgt tgcaatagtg tatataaagt gttgtaaagt tgtcatattt tttataatat
    20281 ctcactcaat ttaaatatca tttttttctt taaattgtag caagatgttc tatctaagtg
    20341 tagtttcata gaaatatatg tcatattgtt ttttgtctta ctattataaa aaagattaaa
    20401 aaattccatt tctatatcat ttagacatgt tagagcattt tctatcttct ctttttctat
    20461 ttctatatct tctttttcca tttttaattt tcttaatctt tcctctcttt ttaacacctc
    20521 attttccaca gaagaactta tgttatatgt gttactagtc ttttctgtat ataccattgc
    20581 tccacatcca gagtattcat tctcacatct ttttatgtcc aaattaatat tctttatctt
    20641 tatatccaaa tacttataat tatgtaatct ttcatctgtt tctttaaata atatatcttt
    20701 tttgttttcc atagtacttc tcctttttta tatacttatt attagcttca aatttacaat
    20761 aatctcttta gtgcacagtt ttttactaat ctcacaactt tcaagaacat attgttctat
    20821 aactgtataa aaaaaacttc ttctatattt tgttctaaaa tactagaaat cttcttagcc
    20881 ataagaagac caggattttt tatacctctt tctatttgag atatatagtc atttgtaatt
    20941 ccagcctttc tggcaagttg aatttgtgtc atacctttgc attttctata atatttcaag
    21001 ttatttttaa acattgtttt atacctccat taccattaag aatattttgt tcttccacac
    21061 ttagattata tagaatcatt tgttctttat caatagattt tagaaaaaaa tattctttta
    21121 tattttatta gttttatttt ttagaacaat ttgttataat ctatacataa ggtggtgtta
    21181 taatgtttgc caaaagatta agagaactta gaaaggaatt tggattgact caaagagaac
    21241 ttggagaaaa agtaggcgtt tcccaaagag tcttagggta ctatgaaaca gaaaacagat
    21301 ttcctgatga acacatttta aacaaattgg ctgatgtatt taatgtatca gttgattacc
    21361 ttcttggaag aaccttagtt aaggaaaata ttgatacagt agctgcacat agaaaaaatc
    21421 cacatgaaga gttacctgaa gaagcacaag aacaacttaa tgattatata gaatttttac
    21481 taaataaata taaaaaaaaa taaaccatat gatgagcagt ctatttttct gctcttttaa
    21541 tataatttaa aggcaaacat acattctatt ttagggggat ttttatgaat aatttggata
    21601 agctttttga attagcttct caagaagaga taataattca ttataccact tatattgcag
    21661 gtgatttaga agggctatat ataaacaaac atggtattaa aattatatca ttactcagta
    21721 atttaaaaca aaactcaaaa aaattgacat ccatcttagc tgaagaactt ggacatcatt
    21781 tcactagcct tggatactat gtatcctctt ataacgatta ttatacaaaa attattatag
    21841 ataagtgcga aaataaagcc ttaaaatggg cttgtgagtt cttaattact gaagaagata
    21901 taataaacat aattaattct ggcatcactt gcgtttatga aatggcagac atacttaatg
    21961 tggatattac tttctttcaa aaaagattag aatttttatc attaaaaaaa cagtctttac
    22021 aacttggaaa taataaatat ttaatattaa ctaatttgcc gtatttctac atatttgatc
    22081 caatttcata ataaaaatag tagtaatttt aactggctta acagtaaaat ctatatattt
    22141 attttaacaa attttggttt ctataaattc aatattaata tataataatg atatcatatt
    22201 atttaaaatt ctaaaaacaa atatatgctt ttgttaagaa aggttgtttg atgaatgtat
    22261 aaagaaaagt tgtttgataa ttattttaag ttcttagcac tattattttg gccaattatg
    22321 tggtataagt ggatagtaat ttcaaatggt actcttgaaa atatgttatt taccatatat
    22381 gcaatcgtcg caattatttt catcatttta tattcggtgt ttatgataaa atataaagac
    22441 attacacaaa tagatttctt ttacaggata agtactctac ttgcttttat atttacactt
    22501 tttagctttt taatataccc aaagagttta tttttcttgt atttaaagat tatttttact
    22561 ggaatatacc tttattattc aatagtaaaa actcttaaat ttaaagatga tgaaggtgta
    22621 gtgggtatta tgagctcact tttattaatt gtaataactt tgttctacta aatttaattc
    22681 tatttgactt aatatggctt taaatattag acatctacat tattttctga tattatttaa
    22741 gatggtagtc ttatattaat aatgaaatac actatgaagg agttaactat tatggaaaaa
    22801 aaagttttag caacagttgg agaaaaagag ataactaata ttgatattga aaatgcatta
    22861 aaatcattag acccttatca agctatgcaa tttaaaactg aagaaggaaa aaaacactta
    22921 ttaaatgatt tagtgaatca agaattattc ttcttagatg ctaaagaaga aaaattagat
    22981 gaagaagaaa tatttaaatt agaaatgaaa aagatagaag aaaatgtatt aaagcaattt
    23041 gctataaata aagttttatc tagtgttaat gtaacagaag atgaaaaagt aaaattcttt
    23101 gaagctaata agagctcttt ctctaaacca gaaagtgcaa ctgctaaaca tatattagta
    23161 gatagtgatg aaaaagctaa agaaatactt gctcaaataa aatcagaaga aatatctttt
    23221 gaagatgcag ctcttaaaca ttcttcttgc ccatctaaag atatgggtgg tgatttagga
    23281 acattcggta gaggacaaat ggttcctgaa tttgaagaag ctgtgttctc tatggctaaa
    23341 ggtgaagtaa gtgaaccagt taaaactcaa tttggatacc atataataaa attagaagac
    23401 cttcaagaaa gtacagagtc tacatttgat gaagttaagg ctgaagttga aaaaagttta
    23461 ttatatcaaa aacaaaatga agtttatgga aataagataa atgctcttaa tgctaagtac
    23521 ggaaaccttg taaaatacaa cgattaatca taaggtcata tataaaaaag ctgtcttttc
    23581 acaatattta ttagaaaaga cagcttttta tattaaagtt taaatattca gtttcatatt
    23641 atcattcttt tattgtaaag aactcagctt aaaagtttaa ataagatttt taattatcat
    23701 tagctaaatt tttatatcca cgtattatct cataacagta acctattaca tctcttcttt
    23761 ttattatccc aataaatgtg tcttggtcat ctataacagg aatgaaattt tgatttaaag
    23821 attttataac taaatcttca atatctgcgt tgatggaaac aggagaatta tccatttttc
    23881 tatttatatc tgtcactgga acatcttcca atccctttaa gtccagattt aaatcgtttt
    23941 ttaatgtcca taaaaaatca ccttctgtta tagttccaac atatttacca tccttactta
    24001 ttattggaat tgcagagtat ttgtgatatt ccattttttc tagtgcttgc cttatagtgt
    24061 agtcttcata tatatatgct acttcacttt ttggtgttag aaagaataat atgttcatta
    24121 cactacccac cgttactgaa aacttataaa tattactcaa tatttataat gttacttttt
    24181 tgcagtaact ttctcctttc ttattttcta agtattctta atactatacg ctgtaacaag
    24241 cgtttttcct ttgctcattt taatcttatt atgctttatt aatattttta tatggtctat
    24301 cagtatcact tattctcttt ttagaaaatt tactaaaaat taattgactt aaacttagcc
    24361 ataataattt tactctacac tattaatttt aacatattta tctcattatt aatgatttta
    24421 ttttaataat tttaatttat tttgctatta attttattta caaaaactga aaaaaccgct
    24481 aaatgattag cggcttatct ctcatattac tagaacacta atatatatga atttttaatt
    24541 ataatctaac tacgttagca gcttgaggac ctttagctcc atctactact tcgaactcaa
    24601 cgctttgtcc ttcttctaat gttttgtatc catctccagt tatagctgag aaatgtacga
    24661 aaacatctcc ttcaccttct acagatatga atccaaatcc tttttcgttg ttaaaccatt
    24721 taactacacc agttttcatt aataaatcct cctaaaaaaa cacaaatatt tagctactct
    24781 tttctgtaac cttattacta ctctatcata tatagctatg tttgtcaatt attattattt
    24841 ttatacatta ataatcaatt tttttacttt ataattttaa atgattatta tcttttacac
    24901 tttatttttc tttataattt tttaataatt tatttttatt atatggaatc ttatggactt
    24961 atcactccag cctaaatccc atggcaccaa cattctatca gtattatggc aagttaccaa
    25021 aggatatcct cttgagtcta atcctgtcac tgtcgaaaca tgtgttattc tgcctttctt
    25081 ctcataacca acaaaatccc ccggacgtaa attataagct tctttgtata cttcttcata
    25141 ggaaccttta gcaattaatg aacctcttcc actatacagt gcataatttt taaaagcttg
    25201 tgcatttacc catgcttttg tacctgctct ctcgctataa ttccaaattg agttcttttt
    25261 gaaccttcca ctttcaaaca ttatctgtga tgcaaagttt gcacaatctc caccttctgg
    25321 attataatcc ctatagtttg gattaaattt cataccatgt tcttcatcag ctgcggctcc
    25381 acagtattta tgtgcataat ctatagcctt tttttgttca tctgtaagct gtaactctac
    25441 accatcttgt tgcccaatat agtttcttat atcctcagat tttatatttt ctaaatttaa
    25501 agagtctgca aaagggtctg tgtaccactc tttagttatg acatattgat tatctataat
    25561 ttttacattt agataatgat atgtacctat tctaaaggca ttttctttgt ccttttgatt
    25621 ttcatatgaa tacttatatt cagtcgatac tgaacagatt ataccataga ggtctttttc
    25681 tttttctttt atttttttaa tcttaaccct tgtctttatg tctttaaatt ttacaccttg
    25741 cttactagac cagttttcta aatacttcat cttttttact tcattttcat aagcccacag
    25801 accaaatttt ttatccgtct cataaagacc ttttaaaatg ttttcatttt tctctaatat
    25861 tgccttattt ctgtagtcaa ataagttttc aagcaatagt ttatattggt cttttacatc
    25921 atcaccttca acatttgcag attccatgac tttttcttcc atatttttca tacttaaatc
    25981 attgattaaa aatacacctg ctgtagtagc taaagacaaa aatacaaatg ccattatacc
    26041 tttgatgtac ttattcttat ttttcagtat tttcaaagct acacctccca aatagtacac
    26101 cttataaatg aaattacaaa gaagattctg tcatatacaa taattttcat atttaataat
    26161 tctctatttt attatgtcca atattaaaaa ttaattgtat caatacactg ttttttttac
    26221 aattttttat tttataatct acttttttct tttttttata gtaatatata tgtatataaa
    26281 tattttggta tcattataat taatacatac taatggaggg ttttttatgc aaaaaaaagt
    26341 cgcagcaatt aatgacttat ctggaatagg aaaatgctca ttatcggttg ctatacctat
    26401 actttcagca ttaaaggttc aatgttgtcc atttccaacg gccatacttt caagtcaaac
    26461 tggttatcct gaatttactt tcttagactt tactgatgaa atggtaaaat attcaaatgt
    26521 ttggaaaaat ttaaaagtca attttgatag tatatatagt ggttttttgg gttcaaagca
    26581 tcaaattgag atagtggcta attttataaa tgattatccc aatgctttta tcgtagttga
    26641 ccctgtgatg ggtgataatg gagttatgta tccaatattc acagaagaaa tgagacagga
    26701 aattaaagaa ttagttaaac attcagattt aactactcct aatttaacag aagcttgttt
    26761 cttaactgga aatgattata ctaaaagcga ttataataga gatgagctta tatatattgc
    26821 aaaatctgta tctgatttgg gacctagcaa agtcgttatt actggtatat tagaagatga
    26881 taatatatta aatttggctt atgatagaga taatgaccat gtattcttta catcagtcaa
    26941 atacaataat tgttcttaca gtggaactgg agatatattc acatctatac tttgtggtat
    27001 gttagtaaat aaacatgatt tgggagtagc ggttaatact gcaacagatt ttatatataa
    27061 aactataaat tacacatctc aatttgatac tgatagaaat gatggagtta tgtttgaaaa
    27121 ctttttatca gatttaacta atatataaaa tcaaaaaaac tatccatttt ataaatacct
    27181 ataaatcata aaatttaggt atttacaaaa tggatattat ttactaaact attggtattt
    27241 caattgttac catagcacca ccagttttca cagaattttc aatatataaa attccattat
    27301 gtttttgtac aatattattt acaatataaa gtcccattcc gtaatgagat ttagaatttc
    27361 tactcaaatc tcctgtataa aactgttctg tagcttttga caaatctgct ttagaaaaac
    27421 cacttccaca atctgtaact acaaatttta agtatttatt acttactgat acacttatgt
    27481 atagtttact ctggcttggt gaataatcta tagcatttga aattatattc ataatagctc
    27541 tgaataacag ttctctatct atagttatat ttttaggcaa attatcttgt ttataaaact
    27601 ccacatctaa gtttttagta ctagctaatg cttctatttg cagtaagaca tcttttataa
    27661 actcactcat attaattgct tctttattta atatatagcc attctctgtt tttgatatat
    27721 ctattaaagt attaatatat ttttctattt gagtgacacc ctttgagata tattccatgt
    27781 attctaataa ctcaggattt tcatttattt caattaataa gtcagtattt ccatgtataa
    27841 ttgttaatgg tgtttttata tcatgtgcca gtgcagatat ctgttccttt ctattttctt
    27901 ctagcatcca ttgtttttct aaagaattct ttaacgccaa cttcatttta tccatagaaa
    27961 aaaggatatt gttaatttca taaattttac tagattctac aacaaaatct aaatcctgtt
    28021 gttctatttt ttctgtagta ttttttaaaa gctccatttc aatattaaat ttcttgccaa
    28081 atacttttga taatataaca atttcaataa aaaatattat actaaaaata atcataccta
    28141 acatctctgg ttttggtaaa tatgctctta aaactggaga actatactct gatactagtt
    28201 tgtattttat tataaaaact tcatctttct taaaaaactt tatataactt tctgaatatg
    28261 catgcctttc ttcaatatct ctcattaaat tccatacttg ttttgattct tttttattaa
    28321 aagtgcctga gatcaaattc ccatctaaag tataaacacc atactcgtat aaatttggaa
    28381 ttatatcttc aattgctttt tcacttgaaa taatcttttc tttatattta tcaaattgtt
    28441 tttctgaata attagctggt aatattacac ctgatgataa taatacagaa aatgataaca
    28501 ttaaaagaag tgcaaatgaa attgtcataa caaagaataa agataaatat tttataaaaa
    28561 tagttcttaa cttttcaact tttttgttgt tagatttttt acttctaagc atttgtgcca
    28621 tatcctccaa atattttaat taattcataa ttaataccta accagttttt atttgattat
    28681 tttatatttt tcattgctaa gttatatttt aacataataa tataaatata atgtaaataa
    28741 acagtcaatt tttatttatt cttctgactt tttaccttcc catttagaaa accaaataca
    28801 taaaattaca aatgctaaaa ttgttacaaa accacacatt aaacctgttg attgatatgc
    28861 ttttattgat tcaaccttta tatattcaac cgttttagaa cttgaaaaag acgaccaaat
    28921 agttataaat ctaacacccc atgcacaagg aaaatactgc caaatgccag aacccaatcc
    28981 agttaataat aatgctgaaa gtaacatttc aactatacct actccaattg atgttccttt
    29041 tccgaacctt aaacttaaga ataaatgtaa tatgtattca aataaattac acccaattaa
    29101 aattagaatt gaaatcatat aaaagcttga tgtaaagtaa gccttagata taccaaattt
    29161 aaaacctaat acagacacta atgttgctac aaaaccaaga catactaaga ttatatattt
    29221 acttataaga gtaagatatt ttggattaga tgttgttaac atatgtttat aattccctgc
    29281 ataatattct tgttcaacaa acattgaaca cacaacacct gacaataaag gaaaagctat
    29341 tgctataact tgtaaatatg ctactatctt taatatatta tcagctcctg aaaccttata
    29401 ataccataaa aacaatccca tccccattaa agcaatgcaa atgtgcatta gtattataaa
    29461 atttctcttt aattttatta aatcagaaca aaatattctt attagttgtc tcatattact
    29521 tcacctctct attattgaac caagctcttg taactaaagc aaataataca aataaaataa
    29581 cagatattaa tactcctggt aaaataacag cattatttaa aagttcactc ccctctggta
    29641 caggaagccc atttggtaga atatgcaata caacaaccat taatcttgaa ggaatcgaat
    29701 atggaaatac ataccacatt tctgtagttg agaaaacagc aactccaaca atagtaaaga
    29761 acatatttgt tagaactgta acaaatatac caaattttga agctaaaaac atacaaagag
    29821 gaatctgcca cataaatagt aaaataatta atatagttgc aatgatattt tgacctattg
    29881 aaatagtttc tttatagatt atcccaacaa aaactacacc tattgcagaa ataatcgatg
    29941 ctatagaaca acaaataata cagtaaatca tttttccagc ccaaacgtct ttcatttcaa
    30001 ttggcaatgg taaaatacca cgatatttac ttttttcatc ttttaatact attaaagaag
    30061 atattaatgt taatgctcct ggaagaaatg tcgtatacca ccagttgaaa gcagcatttt
    30121 gccctccacc tagtccacac aaaagtatac aaaacactgg aactatccat atcaacttca
    30181 ttccaaaagt tcctttcatc ttttgaaatt ccactctaat aaatctttcc atattactcc
    30241 cctctctttc tattttcagc tacaactttc ataaaaagtt tttctaagtt ttgttctttt
    30301 gatacttctc cttgataacc aattactcca ttagaaatta ttccgatttc atctacgact
    30361 tgttcaactt cagacaagat atggcttgat aaaataactg taattccttg ttttggaaaa
    30421 gaacgaatca attttctaag ttcttcaata ccaatagggt caagaccatt tgtaggctcg
    30481 tctaagatta aaagttttgg gtgatttaat aatgcaatag caataccaag acgttgcttc
    30541 atacctagag agaattgacc tgaacgcttt ttaaaagtat ctcttaagtc gacagtctct
    30601 aaaacttctt caattcgaga gtcaggaaga ccaagtaaag tagtatggac ttttaaattt
    30661 tctcgtgctg ttaaattctc atatatagca ggagactcaa taagagaacc aatatttgat
    30721 aaatcctttc tagtccatct atgtccctca aacattattt ttcctgaagt tggatttaaa
    30781 atcccagtta tcatttttaa taaagtagat ttcccagctc catttggtcc taataatcca
    30841 tatatagaat tagatttaat tgctagtgaa atattatcaa ctgccatctg ctccttaaat
    30901 tttttagaaa ctccttttac ctgcaaaata taattattca taattttcat cctttctttt
    30961 gtcaaactta tttacaagaa tcattctaaa tcataaatat aaggatttta taagaattaa
    31021 aaaacaaaaa aaagatgtgt taaaaacaca tcttttttta tcttaattct attaattttc
    31081 cattgtagta tatctctact tcttcaatcc aaatgctatt atcttcttct tggatgacat
    31141 ttttaataat attatttata gtatatatta tattttgttc attcaaataa tcatctttcc
    31201 aagaaactct acttttttta tctggttcta tcaagtttat tttaacaaga ttatcttttt
    31261 ccttaacttc tacttccatg tctaaaccat taaaatactc atttgataat gtatctaaga
    31321 ttaatcgcag tttatcctta agtgaacttt cttcatcaat ctgtaagtac tttactattt
    31381 tctcatcctt tgaaattatc tctataggta ttttagtagt ttttttagaa ttaatcattt
    31441 tactagttgt ttcttctttt gcatcttcat ccttctttac aactgctgat tctttagaat
    31501 caactagctc aactgcactg atgctataat ccatacatgc tgtactcaat aaagtagtag
    31561 caattattaa aaaacttact gctattttat tcataagtat ccctctccta attctctttc
    31621 gatacttatt ataccatagt atagattata tttttatact tttaaatcaa tttataaatt
    31681 attatagtaa attatttaca attctaagct atttgaattt atttttatag tatattcttt
    31741 ctctaaattc gacagatttt tattcaaaag cccttttatt tccctcgtat ttctatactt
    31801 gttgctatgt tcttcactat gttcataatc atatgaatca ttgtcatatt cttcatcatt
    31861 attaaattct tcaattgctt cttttgactt tatatcacaa ttaaatttat acttatttac
    31921 tggtatatca agtcttacct tagaatttgg aacttctatg tccaggaact tagcaattgg
    31981 catattagag tacaagtaaa attcactttc ataatttgaa tttctaccta ttttctcttt
    32041 tatatttaca ttttcaggta tatactcttc tatattattg ataaatacat cttcattctc
    32101 tgaagatata tccaatgact ctgattctat gtttacattt ttaacgccta aaattgattt
    32161 tgttgacaag tgaagattgc tattagatat taagtttagg ttttctaatc tatttacttt
    32221 gttctctgtt atagctctac taaaacctcc ataagaagtt ttatatgtta tagtatttga
    32281 agctacatta tcatatacaa ataagtatga acttgtactt gatgcattta tgtctacatt
    32341 atttggtaca tatattataa tttctctata atcatgtgaa aacatactat ttatagatgt
    32401 atttaataat tggtcgaaat ttttaatctt tttaatttta ttttcatatt ttctttcacc
    32461 ttttacaact aaagtcttat cttttaaagt tacattgtat ttgtaaaact cattatttcc
    32521 tcttgttgtt acacgcacat cttcacttga acttttcttt attgtaacgt ttatattgtc
    32581 aacagatata tctaacttgt caatatttac tttttcttga taaagtttat tttctttttt
    32641 aaattcagct tccttttcta aaccaaagtt tattaggctt ggcataacta aaatccctga
    32701 ccatgttgtc cctattatac ctattaccaa taaaactgca gcaaatatag caagtttttt
    32761 attcatgttt atcttctcct ttcttatttt ctatatcttc aaggtcctta tatatcgcct
    32821 caaaatttat actatcatca ttatattcat cagtttcttt tatgctttct tcttctctat
    32881 tgtagtaatc attattatat gaatcttcat taatgtcttt attcaaatct tcatcattta
    32941 aagtagcttt ttttcttttt tccatctttt catttgcctt tatataaata ttttttctct
    33001 ttatccaatg tatataatta tttagtaatt gtttacctag ttttatagca aataataaaa
    33061 tttgccatgc aagtatctca agccctacaa atgctatggt tgcgaaaata caaaacatca
    33121 taacatctgg aaccattgct ataaatttaa tcacaaatgg aattaatata acaaaagcaa
    33181 ttaatgaaca tactaatgca atagtaacag atacaatagc acatacaaac gcaaatgctg
    33241 gaacaattag aaataaagat aacactacta ataatccctt tataacttgt ctagataatc
    33301 cccctacacc ttcttctata cttggtgtaa gtttatcatt tatattttct tttgatttat
    33361 tgtacttttc cttagcttca tctttcaaga tagagtaatc cttttttata tttgatttaa
    33421 acctactaaa tttaccattt aatatatctg tattcattat ttttccatct atattttctt
    33481 ttgatttact atacttttct tttgcttcat cttttaagat agagtaacct tttttcatat
    33541 ctgatttaaa tttactaaac ttatcattca aaacatctgt atttattatt ttttcctctt
    33601 caatattttt ttctttagtc tgcaagataa gttctttggc tatagatttt ggtgaaccaa
    33661 gtgatgctat tatctccata tcactctttc cctctataag accatctacg aaatactctt
    33721 cataatctct caatatatca ttaacttcgc tctcagaaaa atcttttttt agataatcct
    33781 ttaaaatttc aagaaactca gttttattca agttcattac ctccctcatc ttcacttatt
    33841 aaaatctcaa cagcctttac aaattctctc cactcttcca tcagattgga taaattctct
    33901 tttcctagtg aagttattct atagtatttt ctagcaggac cttcattaga ttctagtata
    33961 tatgtttcga aatacaaatc ttttgtaagt cttcttagaa taggatatat tgttccttca
    34021 tttacatcta ttactttaga gatgttatgt actatctcat atccatacat atctttctta
    34081 gatatgagag caagtacaca aatttctaaa acaccctttc taaattgtgt gttcatatac
    34141 tccatccttt ctttaaatac acagtattgt gttttacaag gtactatgtt aaaacttctt
    34201 atatcctcat aataacacag tactatgttc tgcacaatag ttatttttaa atattcttgt
    34261 tgattaaatc cttctataaa tgtataatac tctaatcaga tatattttat gaaagtggtg
    34321 ataaattggc taaaatgaaa gatgataaaa caatattaat cttaactgct caatttggtg
    34381 ctggacatat aagtgctgca aaagcagtca aagaatgtat tattgaaaaa tatagtaact
    34441 ataatgttgt tatacaaaac tttataaatg caagtattcc catgatgaat aaacctatgg
    34501 taaaacttta tgaaaacaat acaaaatata ctcctggatt atataattac tattattact
    34561 ttaagaaatc gtttgattca agacatgatt tatctcataa attatataca cctaaacttt
    34621 ctgagtatat tgctgatata aatccagatt tgattatctc tacatttcca ctagcggctg
    34681 cttgtgtaaa taactttaag ataaaaaatc ctgatataaa tatacctaca cttacagtta
    34741 taacagatgt tgtagatagt atggaatggg tttttgaaaa tacagatttg tattttgttc
    34801 cttctcctga aataaaaaat agattttttc agaaaggaat aaatccagac tccataaagg
    34861 ttactggagt tcctgttgat aagagatttc aaattgaaag taaagaacta tgttgtgata
    34921 aatatagact attacttcta ggtggaggaa gaggcctatt tgatatagat gaggatttta
    34981 tgcattggat agatgaattt attgaagaac atagtaattc tatagaaatt acaatagtta
    35041 ctggtaaaaa caaaaaatta tatgacaatc taactcataa aaaacctcta aaaaatatta
    35101 aagtacttgg atttgtaaac gacatgtata atctaataag agaatgtgac ctaatgctaa
    35161 ctaagcctgg aggagcaact atatttgaag ctattcaatc acaaactcca gtactcgtga
    35221 aaatgccaaa agttggacaa gaaattgaaa acgctaaatt tataatagat aagggtcttg
    35281 gcatgattta tagtgatgac ctagacctta aaaacatatt ttataaatta gtatcaaatg
    35341 aatttgattc tataataaac tttatgaaaa aaaatttaga agaatttaaa acagttattc
    35401 atccagagaa aattgctgat tatatatcag aattaataga taatcattac agttaaattg
    35461 tactattaaa aaatttcaaa cataaaatta aaggcaatca agtatgcttt tacacttgag
    35521 aatttactca tagtgtttaa taatacttga ttgcctttat catatcaaaa tcaaattgtt
    35581 atattagtat atatttttct tgtactgcat atacagttgt tgtatttctt ccatacttct
    35641 ctttaattct atttgtaaat ctgaagcagt ctggtaatcc ttattttcta tagcttctct
    35701 cactctagtg aatagtgatt ctctagttaa agtatccttc ataatattga actttaaatc
    35761 cgatattgag ttccaaacta cctcatcaag cgcatccata ttttcttttg tgtgtatctt
    35821 gacaatactt cttatttttt gaatcccagc ctctattatt ctagttttta attttttttg
    35881 ccacttatct atagctccaa tcttaaatga ttctattata ctatcagtaa atacatcacc
    35941 ttgttttaaa gattttaatt ttgaagcata tatttctaag tttttcatat tttcataaac
    36001 tgtagccggt ggtattccaa atcttgcatt tctttcttcc aaactataat gttcaaatac
    36061 atcattttca tctctatatg ctctatcttt ttctaaatag aaactttctt cacctacatt
    36121 tttagataac tctttttcaa gttcttttgt actaagacca ctcttagctg ctgcttttat
    36181 accatccaac attgtttgat aacatcctgc tattactaaa tacgtgttag atagagggct
    36241 tggtgacctt aactcaaatc ttacagtctt tggatttttc atatctctta ttaatccaac
    36301 aagcactgac ctatttcttg atggaatctc ataactatgc cctaaagatg taactatgca
    36361 tacaggagct tcaaatccag gaactaatct attaaatcca tcattagaag ctgttacaat
    36421 tgggtttaat acttcataat tgtaaagaag tcccataaga gccccatatc ctagttcact
    36481 tagataatct tcttttaaat cttttggagc aaatagattt tttatacttc catcctttaa
    36541 cttcgcactt actcctacat gtgtatgtcc accacttcct gctactccat gaattggctt
    36601 tgctttaaat gtaacttcta gtccatgtga tgtaaataca tcctctataa catctcttac
    36661 taataattca ttgtctgctg cttgtaatgg tgtagaaaac ttccaagaaa cctctaattg
    36721 ctccatagca tggtttgttc ttccatctat actaatagaa ctttgtattc ctccgacctc
    36781 tttgtgagcc atttcagggt ttacacctag cttttgaagt ataattaaac ttttctctaa
    36841 acaagttctt ataataccat gagttctttt ccagtattgc tcttttaggc tttgtgatac
    36901 atataatttc tctaagtcag ctttatcctc aggagtatta acccagaact caagttctgt
    36961 agctgctgtt aacattattt cctctatatc atctactgaa tctattccta tgttatttat
    37021 tacatgtgga tattctctaa atatttcata cattgacttt ttaaagtact tatctgcttt
    37081 ttgaagtact cctctagaac atactttttt attatcatgt attaaaaatg caggtatctt
    37141 taatgttcca acaggtagac ctacttcttc gtctatatat tccatattgt aatctacata
    37201 ccaatgacaa cttttatctg gcattaaatc tactttcgca ttatttaatg tagctatatt
    37261 ataaagctca acacttgaac catcagtctg tatagctgat tccaaaaatt tatctatatc
    37321 ctccaaaaat aattctacag gaatcttttc atctgttgca tttcctccta aatcaacccc
    37381 cattaaggaa acaaatctta tatttttatt gctttttagg atttctctta attcttcatt
    37441 agtgtgttta tctttctcta ttacgtataa tagactatcc atttttccac tctcccataa
    37501 tttttatgta tattttattt tgttaaatac aagataaatt tcattttcct tacattcatg
    37561 aatttttctt gcaaattatt cgtgttttat tcgtgttttt atttatatta ttatatatca
    37621 agtataaaaa gttcgcaata ttttttattg gaaaaaatat tatacataca atagtttaac
    37681 atttttacaa atatggggta tactaaaata aaagtatttt tatttgaaaa tttaatttta
    37741 tttataatat aatctatagt aaaagaaata ataaaaaaat ttaggagata aactttatgg
    37801 aatacataat tttcgatttg gaatttaacc aaggatttga taaaaaactc aataaaactg
    37861 tatccaatga aaagtgtcct tttgaaatta tacaaatagg agcaattaaa ttggattcta
    37921 aattcaatat aatagatacg tttaatagct atgtaaaacc tacaatttat aaagacatac
    37981 atccctttat tagtcgtatg actaatatta aaaattctga ttttaatgat tcgcctactt
    38041 tccctgaggt ctacaacaat tttataaaat ttatatcatc acaagaccct atattatgtg
    38101 tttggggagt tggagattta aaggaattat acaggaatat caactatcac aagctaccat
    38161 caagttcctt acctaaatct tatattaata tacaacaaca tgcatctaaa tatttcaata
    38221 atccagcagg aaaaagcatt ggcctacaaa atgctatttc tatattggaa cttgatgaaa
    38281 aaatgtctta tcacaatgct ttaaatgatg catattatac tgctaaagtt tttattaaga
    38341 tatacaatcc aagtatagtc ccagatatat atctttatac gagtataaaa cctaaaacta
    38401 taagatattc taataaaaaa agagttgatt atgataagtt atttgatgaa tttaggaaaa
    38461 ttttaaatcg tgaattaact aaagacgaga aaaaaatcat taacttagct tataatatgg
    38521 ggaaaacaaa tcaatttaca ttagaaaatg ttaagcaaag aaaaaacaaa tagagtttat
    38581 ttagataaaa aataggcatg tagattaaaa aactagttaa ctttaaattt atatctacag
    38641 cccaattttt atcgtaatta atttttattt tatctctaat tcaactggac aatggtctga
    38701 acctaatatt tcagtgtgta tatccgcact tactaatcta tcttctaatt ttttggatgc
    38761 acaaaaataa tctattctcc accctgcatt attttttctt gcattaaatc tatatgacca
    38821 ccaactataa acgccttctt tatcaggatt aaaatatcta tatgtgtcta taaacccact
    38881 gtctaataat ttagaaaact tctctctttc ttctttagta aaacctgcat ttttcatatt
    38941 atttttagga ttttttaaat ctatttcttt atgtgcaacg ttcatatctc cacacacaat
    39001 tacaggctta tgattatcta gtttggttaa ataatctata aagtcgtctt cccatctagt
    39061 tctatattct agtctcttta attcagattg agaatttggc gtatatactg taacaaagta
    39121 aaaatcttca aactctagag ttatcactct accctctttg tcatgttctt ctatatttat
    39181 tccatacatt acttttaaag gctctttttt tgtaaatata gcagtacctg aataaccctt
    39241 tctctcagca taattccaat attgaaaata tcctggtaaa tctaactcta tttgcccttc
    39301 ttgcaattta gtttcttgta aacaaaatat atctgcatct acttctttga aaaagtctaa
    39361 aaatcctttc ccaacacaag ctcttattcc attaacattc catgatataa atttcatact
    39421 tatactcctc atctaaacat tgacacactc cccatagcta aagatggggg cttttcaaca
    39481 attttattgt aaattcttaa tttactttta ttttaacaat actatactat aatttcatct
    39541 ataattacta tttacttaat acctaaaaat atatgtttta atcaattttt aacttttttg
    39601 ttaaatcttc agggctcatt gaagaaacat acatatttgt tccaagttca aatcctccaa
    39661 aattatattt tcttgggatt atgtgcatat gaacattaaa atacgatttt gtttcaatct
    39721 ttgttggatg agtgtgaata cataagttaa atggcatata tccattgata ttgtataact
    39781 tcttaaacaa cttttcaaat attgtagaaa gctcctgtat attattatca tttaactcac
    39841 caaactctat tttatcttta aatattattc ttacttctcc actatacttg gttgcatatg
    39901 gtataagtac caaaaaagct tctccattat aaacaactct tctatctaaa cttatttcat
    39961 tttctattaa atcatcatac aaagagcttt tattgctgtc ataatactcc tttgaaacta
    40021 acagttcatt cgtaatttca ggtggaataa aagacataga caatatttga gcatgtggat
    40081 gcatcaaaga tgctcctgcc tttctcaaga agtttttgaa gatactaaca tactctactt
    40141 tatcatcttt cgacaaatct ctaaatctat ttctatacat aaaaaaaaca tcttcaaatt
    40201 ctttttgact catgttataa aaactacgat tatgtttatc gctctctatc attacttcat
    40261 gaacaccata tacatctctt gccatatcat caattatagg aaatttattg tagacagatt
    40321 ttacaagcca tccttcttca ctttctattt caaataatgc atcagttgca tgagcttcat
    40381 ttcctttgca aaatgggcat tcttcatcat attcattagt ttcttcatct tcatttggga
    40441 tatctgctgt atctaaaggt ctttttaacc tatctgtagc aaatataaca acatcattag
    40501 taattggatc tattcttaat tctttcataa ttaacacctc ttagttaata gcctttaata
    40561 taattatatg atatttatcg tatctgttaa ataaatttat aatatttttt ataattttgc
    40621 atatttatta ttatatattt tgtctatagc tgaaagatta taactaaaaa atcactatca
    40681 gtgtatcaga atattatctt actataaatt aatttatgaa tacataattt agtggcataa
    40741 acatgggtat tttactataa tttgttaaaa gtttatttta aagctatatt aatttttttt
    40801 gatgattttt acccataagt atgttattat tatcttgtaa agatgtcttg tattcaaaca
    40861 tacaatttac ataatacaat atacgtattt aaattaaata gggggtatta aaatgaatta
    40921 ttcaaacaga gttagtgcaa tgcaagcctc tccaatcaga aaacttgttc catttgcaca
    40981 agcagcaaaa gataaaggaa tcaaagtata tcacttaaac ataggacaac cagacataaa
    41041 aactcctaaa ggattttttg atgctgttaa aaactttgat agcgaagtct tagaatatgc
    41101 tacatcagaa ggtattccag aattattaga agcacttcaa aattactata aaacttacga
    41161 tatgaatttt gaaaaagatg aattattagt aactaatggt ggtagtgaag ctttactttt
    41221 cactatgatg gcagtttgtg acccaggaga taatctatta gttccagaac cattctatac
    41281 aaactacaat ggatttggtc aatctgtaaa tgtagaagtt aatgctgtta caacaaaggc
    41341 agaaaacggt ttccaccttc catctaaaga agaaatattg tctaaagtag atgataaaac
    41401 taaggctata attctttcta acccaggaaa tccaactggt gcaatttata caaaagaaga
    41461 acttaatatc ctagctgaaa tagctaaaga aaaagattta tggataatag cagacgaagt
    41521 ttatagagaa tttgtttatg atgggcttga gtatacaagc tgtggtaact tagagggtgt
    41581 acaggataga gttataataa tagacagtgt ttctaagaga tacagtgctt gtggtgctag
    41641 aattggttct atcgcttgca aaaataaagg tcttatcgct caaatactta aattatgtca
    41701 aggaagactt tgtgttccta cattagagca aataggagct gttgagttat acaaaactcc
    41761 tgtttcttac ttcaaagaag ttaatgaaga gtacaaaaaa agaagagatg tattatacaa
    41821 tgaattaatg aaggttgaag gtgttatatg taaaaaacca actggtgctt tctatatagt
    41881 tgctaaatta ccagttgaaa atgcagaaga tttcacaatt tggatgttaa aagaatttaa
    41941 caaagataat gaaacagtta tggtttgccc tgctgaagga ttctatgcta ctccaggttt
    42001 aggacgtgat gaaataagat tagcttacat cttaaatgaa aaagaccttc atagagctgc
    42061 tacattatta aaagaaggtt tagagcaata tgtagcttta caaaaataat tttttaaact
    42121 taatttatat aaatttaatg atataaaatg tccccttttc agatattatt tgaaaagggg
    42181 acatttctta attaatatat taattaagac ttagacctga ctatttttca ttttctttat
    42241 atagtgttgg ccagtaatct ttattcactt taattaaagc atctaaaact tgtcttgcct
    42301 tagttggaga gattatagtt ctatttaatg ttaaagataa aatagctttt tcataagatt
    42361 gttcaaagta tgcatcaact gctaactttt cataagctag ttgaccttct aacagtccct
    42421 tataaaatgt tggtatatta cctacatgta aaggtctcgg tccattcttt gtaagaatcg
    42481 cagctacttc taccattgca tcatcaggta agttgttaat agccccatta ttttctgtta
    42541 taactatggc tatttggtgt ttgttatgag ctattgcttc tgcaacttca actataaatt
    42601 ccccatgagc atcattatgc actaaattag aacctataga tgttcctttt tctataacag
    42661 atttacattc ttcaaataca cgcttttctc ttccattcat aacttctctt gctctagtac
    42721 aatttatatt tgatttagct acttttttat caggatatag ataatactgt acatatgtat
    42781 taggtaagta atctggtaca tcttccaaca tatctttaac cattccataa gtgtctaacc
    42841 aagatttatc tctttgttct gcatcaacag gttggaatcc agagtttgct actaaatctt
    42901 ttatcttagg taccaaatct tcaccatttt tatcatacaa atgtgtaaac catccaaagt
    42961 gatttaatcc aaagtataca ggctcaaatg ttcttgaatc catgtctaac aatcttccat
    43021 aagaccttaa caagttaact ggttggtcac acatattaag taatctttta tcatctggaa
    43081 atactctttt taatgcttct gcaacaatag cagcaggatt tgtataattt aatatccatg
    43141 ctttaggaga gtattttctt acagtcttaa ccatttctat catatcacct atagacctta
    43201 acccataagc aaatccacca gctccacaag tttcttgacc aaccagtcca aattgtagag
    43261 gaatcttttc atctaattct cgcatcttaa gaccaccagt tctcatttga acaaatacaa
    43321 aatctacatc tataaatgct tcatctgggt ttgtagtata ttcaagtgtt gctttaggat
    43381 attcttcttt aaataatatt tttccaaatt cccctattaa tctttgacgt tcttctacta
    43441 catctaacat agttacttta tttagaggaa atctatcact cattttacat aaagacttta
    43501 aaagtcctgg agtccaagta ctgcctcctc caactatagc tatattgtat ctttttttca
    43561 ttgtcatatt aatcacccct gttttttatt aactaacttg taagatgatt ataatatata
    43621 aagttttcta catgaatact tttaggtaat cattaaaaat agttcaattt tagtattttt
    43681 ttcaaaattg taattttttt catctattgt atttttcaat gtatttatga aacatatatt
    43741 ccataagaga aagtgctggc actctagacg tatagttaac actattaaaa ttatattgtg
    43801 gagaagatac aaataatttt atatcagcta tatttgataa tgaattgaca cttatatttg
    43861 tcagagaaat tactttaact tgatttgttt ttgctatatt acatgcctta ataacttgag
    43921 cagtctctcc agacatagat acagcaatta caaggtcatc tttagtaata tttgatgcag
    43981 ccaaatacat gagagttgaa tcatcatagt attttacatt tacacctata gctgaaaaac
    44041 gttgagacat ttcagtacat actaatctag aagacccaac accaaaaaaa tatatatgct
    44101 tagaattatg tatttcattt aaacacatat ctatattctc tacatttatt aaattttgtg
    44161 tatccataac atcagtaaaa atatcacttt gacttttagt aaactcctta tttctttcat
    44221 ttctatttga atatgaaaaa actaaaaagt ttttaaattc actatatcca gaaaagccga
    44281 gcttctgaca aaaccttact atgtatgcag tcgaattaaa agtttcattt gctatatctt
    44341 taatcttttt ttgatttatt ttttcagaat tttttagaaa atagtttaaa agagatattt
    44401 catttgtaga taattttttt tgatttatat ctaatttgtc tattaggttc atttatacct
    44461 ccataataat gatttgtagt taaacaactt tctcatattt attatataaa tatacactat
    44521 acaacattta tcttatgttt attatactac aaaaaagaca atacaaatta taaattagta
    44581 ttgcctttta atatttacat tagatagaca ttaaatagac attgcaaaag aaacttcgtc
    44641 tcttacttga gatacagatg gcccataaat tatttggata tctttatcag atacttttat
    44701 aacgcccatt gcacctgtat attttttaaa agcattttca tctactttac tcatatcttt
    44761 aactactact cttaagcgag ttatacagtt tgttatatct tctatattct ccttaccacc
    44821 taaatattta attatggata atgctctctt agtagtttct ccactttgag ctatttctac
    44881 tttatttgat aaaggttcta aatcaaaatt tatatctgtt atttcttctc gtcctggagt
    44941 ttgtaagtta aatctaagta tcaaaacctt aaatacatta taataaacca gtgcatacac
    45001 taaaccaagt attatagaat aaatccactt tgtatttggt tgcataactc caaatactac
    45061 taaatctatt atgccacctt gagtatttcc tattgctact ccaaatatat gcatcatcat
    45121 aaatgatata cctgataaaa atgcatgtat aacaaataat attggtgata caaataagaa
    45181 tgaaaattcc aatggttccg taattcctgt tacaaatgtt gctaaagcac cagctagtaa
    45241 tataccttta accttcgacc tattttcagg ctttgcagtt ttatacatgg catatgctgc
    45301 agcaggaaga ccaaatacca ttataggtat tttcccttga gctaaaaatc tagttgcttc
    45361 tgttgaaaaa ctgattgttt cagggtcact tagttgagct aaaaatatgt tcaatgctcc
    45421 aaatacttct tgtcctccta caactaaaga acctcctact tcagtaaatc taaacatagc
    45481 atttaatata tgatgtaatc caaatggtat taaaagcctt tcaagaaatc caaatacaaa
    45541 ggttcctaaa tatcctaaac tagctatacc aatacctaca ctctgaataa ttgtatttac
    45601 atatggccat atatatggta ttattatccc caaaatagag aatactactg ttgttattat
    45661 tggaacaaac ctagttccac caaagaaccc taaataatct ggcagtttta tattatagta
    45721 tttattatgt aatgatgctg ttattatacc aactacaatt ccaccaaata ctcctaactc
    45781 taatgtttgt atgcctaaag ttacagcttg acccatttct ctcatcatgt caggttcagc
    45841 aagaatacct ctacacccta acatataatt tacactagtg tgtaatacta aataaccaac
    45901 aaaaccagaa aatgcagaaa ctgctttttc ttctttagca agaccaacag atattgatat
    45961 agcaaagaat attgctaagt ttccaaaaag tactcctgtt atagcttttg taaaacccaa
    46021 tattccttga ataaaattat tttctaaaaa aggtatatca ctaactatat taggatttga
    46081 aaatgctgaa cttattccta aaaatatacc tgcagcagat attaatgcta ttggcaataa
    46141 aaatgatttt cctaactgta aaaaaaactc tttcattttt tgtttcattt ctatccctcc
    46201 atttttaaat ttttaaaacg ttttctatgt cataattata tatttttatt ttgtttttga
    46261 aactttataa tttgttttaa aatattttta cataaatagt aattttttca aaactgtaaa
    46321 ttttttcaaa caaagacata gtaacattgt gatatataga aatttaaaaa gagattagaa
    46381 aataaaatta ttgaatataa aatggaaaaa tataaattac acaaagaggt atgagtaggt
    46441 actaacaaat aagaaaatgt ataagaaatt ataaaaaagt acatcaagaa aatttaagat
    46501 gtacttttta gattgtattt agacttataa ttatatagtt aaatgaataa caaagaatta
    46561 atcttagtac tattaaatat aaaaattttt tatatttttt ctatctaaat tcttctttgt
    46621 ttaatatata ttgaagagta tttattgctt ctaaatattt ttttctgtct tcttcagtta
    46681 atttagaaag tttttctcct aaaccatcac ttaatttatc cataaaatca gttgctatct
    46741 tatctccctc ttcagtaatg tcaattagat attttcttct atcaactaaa tctcttttcc
    46801 ttgttacata cttcttatca gttaaatcat caaccatact agttaaactg cctttttcta
    46861 tatttaactt agagcataaa tcagtcatac ttattactcc ataatttttt atgaaaacta
    46921 atgctcttaa ttgtgtttta tttacattat aatctggtgc aaattttttt aggtcttcta
    46981 agtacagact agaataaatc ttaggaaatg tttttactaa aaaacttatg gtatctttta
    47041 ctatatagtt catataatca cctcggttgt tttaaaattt attaaattat ctaaataact
    47101 ttatttcagt ttacattaaa aatattgcaa gtacaatagt ttttgctgaa tgtttaaatt
    47161 taattagtaa tcttatcatt tttttatttt tatttatatt atttctatta aatattattt
    47221 atatagctat tttattaaat tcatggtata gtaagtaaag aagaactctt cacagcgctg
    47281 aagagaagac gctagcccat taaaatggct atcttattta taaataagat agccgttttt
    47341 aattatattt tatctgtaca attctatact cttaggtcca catctacttt tcctaagtct
    47401 tccttataat cttttatagc aggttctaca acttcattta caaattctac aacttgttct
    47461 ggagctctac ctataaagtt ttttgggtcc attatagata gtatttcttc cttgctcatt
    47521 ttaaatgaat catcattcat tataagttca attaagttat tatccttacc ttcgtgcttt
    47581 actctatagg cagctttcat agaatattct cttattattt catgtaattc ctgtctatct
    47641 ccacctcttt ttacagcttc cataagtatt gtttctgtag ccataaaagg aagttcttca
    47701 tttacacgtt tatttatcat attttcatat actactaaac catcagttac atttatccct
    47761 atttcaagta tagcatctgc tgccataaat gcttgaggta ttgccaatct cttattggct
    47821 gagtcatcta atgttctctc taaccattga gtggcttgta ccattgcagg gcttatagat
    47881 tcagagatta tatacttaga taaagatgct attctctcac ttctcattgg gtttctctta
    47941 taagccattg ctgatgaacc tatttgattt ttttcaaatg gctcttctaa ttcttttaaa
    48001 ctttgtaaaa gtcttatatc gttagtcatc ttatgcatac tttgagctat ccctgatagt
    48061 atgcttatta cttgataatc taactttcta gtatatgtct gtccacttac tgcataggaa
    48121 gaatggtatc ccatcttttt acaaattttc ttatctaact cttttacttt ttcgtggtct
    48181 ccttcaaata agcttaaaaa acttgcttga gtaccagtag tacctttaac tcctcttaac
    48241 ttcatgttat ctattctata gtttaaatct tccaaatcaa gaattaaatc ttgagcccat
    48301 aaacaagctc tttttcctac tgttgtaagt tgagcagctt ggaagtgtgt aaatccaaga
    48361 gctggcatat ctttgtactt aagtgcaaat tcttttaaat tgtttattaa atttacaagc
    48421 tttactctta gaagttttaa agcttcattc atttgtataa catctgtatt atctccaaca
    48481 tatgcagatg ttgctcctaa atgtattatt cctttggctt tttcacattg taaaccataa
    48541 gcttttacgt gagacattac atcatgtctt acttcttttt ctatttttct agcttcatca
    48601 aaatttatat tatctatatt agctcttagc tcatctaatt gttcttcagt tatattgatt
    48661 cctaactcat gttcaccttc tgcaagtgca acccataacc ttctccatgt agagaattta
    48721 aattgtggag aaaatatata actcatgtcc ttgctacaat atctgtctgt aagtgggttt
    48781 gagtaagtag tatatttatt atctatcatt atattagcac cttccttaaa tcttttgtcg
    48841 tgtgattact gtgtacacat tagtacataa ataattatat ataattttac gaactataac
    48901 aagacttttt tattttttgt tcacatctat atatagtatt ttttatttat tactattttt
    48961 tatttatatc caaattatct ttttcaatta agtaatccac tatttcacta tcaacaaaat
    49021 ttaatacata cttatatcta attgcatagt atttatcact ccatccaagc tgatttttta
    49081 catcactttc atctgcccca agccttaaac ttattgctgc aaatgaatgt ctaaaatctc
    49141 ttgctgaata ttgagaaagt ccagctaaat ctaatgcttt tttgactata agtctgacat
    49201 ttctatctgt tatagaatta ctcttttgag ttgtaaaaat aaaatcatca ctaggtatta
    49261 ttacctctgg aagcccagaa taattcctgt aatcttctaa aagtttaaaa aagtatggat
    49321 gtaatttaac tactctttct tttcttccct tacctaacct tacatatgag ttatcgtttt
    49381 catctaccat aaggtctttc cactttaagc taactaattc atttaataaa cacccagtag
    49441 taactagaca gactattatt actctatctc ttatatttaa ttttggtagg atacctataa
    49501 gtttatttat ttcttgtata cttagaacat catcttttgt ttttattctt gttactgtgg
    49561 gtttttctac atatctaaat ggatttatat ctatgtatcc ttcttttttt aagaagttat
    49621 aaaaactatg taaataacta tatatctttt cacaagttga tttcgcatat ttagtctgta
    49681 tatagtctac aaaattttta caatcttctt ttgtagcata aatcaattct ttccctttta
    49741 aaaattcttt aaacagtata acctttgata aataatcgtg tttcgtgttt ggatttaatt
    49801 ttgtagaaaa aacattaaaa gtttcatact cataatcatc tagtattttt gtactataca
    49861 taataactcc tttccttttc ataaaataaa atagctatac ttttactata ccatatattt
    49921 ccccctcaaa tatacccctt attcaataga taacttttaa gtttattttg ttatattatg
    49981 aaggttttat gaaaatatca atcttccatt gtgcactaca cagtactatg gtattataag
    50041 ttagtaaaag gtggcatttt tttattaatc tatgaataaa atatgctact ataaatttgt
    50101 attggaggta ttttgatttg gaaacattta gtttgcttga aatttttaag gcagtcattt
    50161 tgggcatagt tcagggaata acagaatggc taccagtaag tagtacaggg catatgatat
    50221 taattaatga gtttataaaa ttgaattttt caaatacatt tataaataca tttttagttg
    50281 taattcaatt tggttcaata ctagctgtac ttgttatatt ttttagaaag ttaaatcctt
    50341 ttgatagtgc aaagaatatt aaacagaaaa aagaaacagt tcgtttatgg cttaaggtta
    50401 taattgcagt tataccatct ggagttattg gaatactgtt tgaagatgac atagacagag
    50461 tattctttaa ttcaacagta gttgctattg ctcttattgt ctatggtata ataatgatag
    50521 ggcttgaaaa gagaaataaa agacctaagt ataaagattt ttctcaagtt acatataaat
    50581 tagctctttg tataggatta ttccagtgtc tagctctcat accaggtaca tctaggtctg
    50641 gttctactat aataggtgca gtattacttg gtacttctag atatgtagca gcagagtttt
    50701 cattcttctt agccattcct acaatgcttg gagctagtgc attaaaactt ctaaaagctg
    50761 gatttggatt tactggattt gaatggctta ttttaggtgt tggttctgta gtagcatttg
    50821 ttgtttcaat tgtagttatt aaatttttta tggactatat caaaaaacat gacttcaaag
    50881 tatttggtta ttatagaata gtcttgggta tagtggttct tgcttatttc tttctattat
    50941 aatgtattct aatttaataa caaatgataa ggagaaaagt tatgagtgtt aaaaaagaaa
    51001 tatttgattg gattaagtca atagctatgg ctattgtact tgcatttgta attctacaat
    51061 ttataagacc ttctgttgta agtggagaat caatgtatcc tactttagat gataaagatt
    51121 atctgatttt aaataggata tcatacaagg ttggtaaacc tgaaaaaggc gatattgtag
    51181 tttttaaaac caatttagtt gatggagaaa caggaaagaa aaaagactta ataaaaagag
    51241 ttatagctac tgaaggtgac agaataaaaa tatcaaattc taaagtgtat gtaaatggaa
    51301 aattattaaa tgaaccatat atacacaata actatacttc tggagatata gatactgttg
    51361 ttccaaaagg taaactattt gcaatgggag ataatagaga aaatagtaat gatagtagat
    51421 tccctgatgt aggtatggtt gatgaagatg aaattcttgg taaggttatg gtgagactat
    51481 tacctcttga taatattggg aaagtggact aaaaaataag agactgaatt ggtaaagttt
    51541 attttacaaa tctcagtctc tttttatttt cttaaattac aaatattttt ttactaaata
    51601 tcttttgatt ctgtaataag tcttattata tcacttgctt cttcattaaa agttgttact
    51661 atacttaggt agtctgttgc tctactcata gctaaataaa ccttatttaa atctcctaca
    51721 aagtcattta cttgataatc ttgttcaata tcatttatag tttgattgta taacatctct
    51781 aattcacata ctattaccgc tttatactct aaattcttta ttgcatatat atttgctatt
    51841 gtagttccta ccttcttact tatatttgtc aaattatctt ctgcacatat ataaggaatt
    51901 tttgcctctt ccaatgcttt ttttaacata tattgaaagt aaatggtttt tccacttttt
    51961 aatttcttct tattataagg ataaacgata gcaacttcag aataatcaag acctttttta
    52021 cttattaaat actcaatttc ccagattaca gaacttattt ggtcatcaag gtcacttact
    52081 tttattatat caacagactt atttccacct ctaagtgctt tagtataaaa gaaagtacta
    52141 aattctgtat ttggtcttaa ttcgttgata tatgagttag aattatttga aaatttattt
    52201 gtaaaatcta caatctcttt agcttgtcta taatttttac ttaagataat cttatcatca
    52261 aattctatac cattatataa ttttttaaat atattcaatc tattagagat attcaaggag
    52321 ttacaagaac acacattaaa tatgaatttt gttttatata aaaactccct tataaaatct
    52381 atttcatact ctaaaaagct ttctgcttca tcaataaaaa tagccttgaa catattttta
    52441 ttttttataa tgttctgtgc ttgttttaca agattattaa aggtcttttc gtaatcattt
    52501 tttaacatgt tataatctac aattaaattg aattttttag ctagtttaaa tataaaagaa
    52561 ctaaatgtgt gaacttctaa attgttatta tctttgtata ataactctat cctctctcga
    52621 agctcattgc acaattgttt tgtatgtgta aatatgacta atttatgatg tggatatact
    52681 tttgctaatt ttatagccct agaaagcata attgctgttt tgcctatacc agaaccacct
    52741 tcaataagtg tattcccata tttaatagaa acaacatctt taatttgaac gtcttccatc
    52801 atagttgctg tatacttata gtcatcattg tagaatgaaa tttttttaaa tttttcattt
    52861 agatgaagtt tatcatttat tatatagtat tctgaacata tgtctagtaa aaataaattt
    52921 aagtttattt catcattctc atcattaaga tactcctcca gcgaaccctt attcattata
    52981 tcttgaagct tatttttatc tattatatta ttattaacaa attcttcaaa ttcatatgtt
    53041 tcctcaactt caacgtatgg cataatgtaa acgtagttat aacttatatt tctattcttt
    53101 tgtcccattt ttagtttcaa aagttcatat tcctcattca taacttcaag taactcttct
    53161 tctaaaataa aaaatatatc ttctgttgta tccataaatt ttataaataa aattcttcca
    53221 tctttaacat acaacaaatc ggtatttatt cctttaaaag gagtaacttt tggcactact
    53281 ttaacgtcct cattgatatt ttcgtaaaat attttctcga actccttcaa ttttagggcg
    53341 tctaactgag aatttatatt tatgtattgg ctcacttaca ttacctcctt ctgttatact
    53401 taattatacc attttgaact atatttttat atatactttt tataggcaaa tttagtaaat
    53461 aaattcaaaa taaatacaaa taaatacaaa actgctaaaa taattttgca ataaatatag
    53521 atatttattg ttatagaata ctttctgtaa ataat
//
LOCUS       DAMJWO010000015        53299 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.016, whole genome shotgun sequence.
ACCESSION   DAMJWO010000015 DAMJWO010000000
VERSION     DAMJWO010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53299
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.016"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..153)
                     /locus_tag="PC366_000970"
     CDS             complement(<1..153)
                     /locus_tag="PC366_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2576509.1"
                     /translation="MKNRLEEIRKERGIKQEELASILQVSRQTIGSLENGRYNPSIIL
                     AFKIARY"
     gene            complement(327..1193)
                     /locus_tag="PC366_000971"
     CDS             complement(327..1193)
                     /locus_tag="PC366_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2576510.1"
                     /translation="MEWINKLNQAITYIEENLESGVDYAEAAKIACCSTFHFQRMFSY
                     IAEVPLSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNVEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPVLEDTREYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYANLPDIELYPNGDINAPDY
                     TTEVWIPIQKPS"
     gene            complement(1419..2288)
                     /locus_tag="PC366_000972"
     CDS             complement(1419..2288)
                     /locus_tag="PC366_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2576511.1"
                     /translation="MDYKTIILNRKSVREYKNIDIKEEYLSEIKKYSESCKKLVPEID
                     VDVRIMNKSEVFNNLDKVAGYKGNMIDSPSYIIILSDIKDNYIENSGYIGESIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGINSDKEVTGIIAIGYGENVSNAKVLNATKTGQNYSK
                     SDMQVVTDKGSTRLGVEDVVYMNEWGNVASIEILEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVVLAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFDLKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            complement(2794..3015)
                     /locus_tag="PC366_000973"
     CDS             complement(2794..3015)
                     /locus_tag="PC366_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576512.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEENEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
     gene            complement(3516..4496)
                     /locus_tag="PC366_000974"
     CDS             complement(3516..4496)
                     /locus_tag="PC366_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576513.1"
                     /translation="MGDTSRFYESVKNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDSLSWKQIVILAECDGKNTTDDIINILSNRYRNIHNMKEKVMEFFMFYENV
                     YLTFEDDIQTLSSVFEITGNKSYITPLYFTIEIDGDNNTNDYFSEITSLLNCMYEKGC
                     RFIEVIGEDILKNKSMREIFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSKNDDTRIKLKEDIKITSLIKRGHTVVRGDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSDGSVKSYSFQKDKRVYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            complement(4660..5532)
                     /locus_tag="PC366_000975"
     CDS             complement(4660..5532)
                     /locus_tag="PC366_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2576514.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYTIFNKKIPKEFDN
                     FKIVQVSDLHNKVFDKNNKVLIDKIESLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINMENESVRIYRGNSHLNLYG
                     LIIPLECYPYLFANNKKLELSDNFVEDNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRIPFVGGVLSPNREFFPKYDWGKYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITLKYEK"
     gene            complement(5696..6247)
                     /locus_tag="PC366_000976"
     CDS             complement(5696..6247)
                     /locus_tag="PC366_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2576515.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQKGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSYVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            complement(6267..7169)
                     /locus_tag="PC366_000977"
     CDS             complement(6267..7169)
                     /locus_tag="PC366_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HDF2576516.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCVSCNRCIDVCPQNISSLFDRTQINNKCDLCGECIKVCLKDAICIMT
                     EKMSVEEIVEEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYDKGINIAIET
                     CGYFDWNKVNDVFEKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPGGKMELLPYHKFGIDKYKALGLEDYIYEFDE
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            complement(7184..9556)
                     /locus_tag="PC366_000978"
     CDS             complement(7184..9556)
                     /locus_tag="PC366_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HDF2576517.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISVSENIEKIDFYKSVSIVAEGIMTLAQR
                     YSNLAKEMSKQETDEKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLKQLAYLVKSSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMIKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            complement(9775..10464)
                     /locus_tag="PC366_000979"
     CDS             complement(9775..10464)
                     /locus_tag="PC366_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576518.1"
                     /translation="MKVKRNINRVAIIVALNLSLALMAGCMSPVSDKNLSSSEQISKD
                     SLKEQVEDKKDESIELFNNYSQKINDAKGREEVKKDLSQRFSKAIIDSGYSITDSKSD
                     GSFVVSINGAEKPPEKNIRSLFYSMSEDDKEGKVTIDILCAKEYPEDDKLSESDKYIK
                     FIYNLFKSLTNTNLTEKEIFSMVEEEFNKGVGVVELPYMKDIHVEVNKVKQSTKVLKL
                     SLVYKFDISNH"
     gene            complement(10705..12084)
                     /locus_tag="PC366_000980"
     CDS             complement(10705..12084)
                     /locus_tag="PC366_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2576519.1"
                     /translation="MLNFMNELLVVLSIFIQFSIMNGILIYKKDSKKNEKIVFYIVLF
                     LIYIIIQISRLFNGGSYFSNINYLFYILAFIAWGGYYNYFYKMDYIKYSIFFYLFSVY
                     YKCLDAVIYRILFFAITGNVISSKESLLVPHLESIKIQIYSNLIIILIYLVFSFFRKS
                     IKLISQDKRNYVYLLFALLANTMNMLVNYVLKKLERFGSLHSEGYYFDNFVNPKLVGA
                     SSIFLILLFKEIIKENRLKSQAELIKNKLDMQYAHYLSIQESHMRVKKLYHDINNHIY
                     CIDNLRNNSKEINEYVNNLKDEIKTFKYIYNTGNMILDIIINEKSEICLKKGIKFTCS
                     INFSKVNFVKPIDVSSIFSNILDNAIEACDKIVDENINKYIRIKGTITKSFFVLKCEN
                     SKLNQLTFNKNILLTNKMDKFVHGIGIQSIKSSLQKYNGELLFENSIDKFILNIYIPL
                     EQDTDSWGD"
     gene            complement(12078..12791)
                     /gene="rgbR"
                     /locus_tag="PC366_000981"
     CDS             complement(12078..12791)
                     /gene="rgbR"
                     /locus_tag="PC366_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HDF2576520.1"
                     /translation="MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELL
                     ESNLKDIDILLLDIKMEKLNGMDTARKIREVDDEMEIIFVTSLIDYVQEGYEVRAYRY
                     LLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
                     TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNAAILESGEEVPISR
                     YRYKEVKEKFLKFLGDTIC"
     gene            complement(13042..13602)
                     /locus_tag="PC366_000982"
     CDS             complement(13042..13602)
                     /locus_tag="PC366_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HDF2576521.1"
                     /translation="MSAMEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYKINKFGGI
                     FYFHKGSPRKIKYTVDYYYDVENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYK
                     DIPPKLYSDSDKKNKVKSILFMNMFIFFMLVVIFIYLLNIEIRNLYSGYGASVTAIVL
                     QIILLILYAVQLYRRLMYYLRLKKFK"
     gene            complement(13698..14501)
                     /gene="zupT"
                     /locus_tag="PC366_000983"
     CDS             complement(13698..14501)
                     /gene="zupT"
                     /locus_tag="PC366_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HDF2576522.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            complement(14652..15815)
                     /locus_tag="PC366_000984"
     CDS             complement(14652..15815)
                     /locus_tag="PC366_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2576523.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     IEIPYVSAGGTGVIATIKGANPGKTVALRGDMDALQVVECTDVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAVLEGTIRLFNPELRKQIPGILERIAKS
                     TAEAYRADAELEYGYLTPAVINDKECSKIATDAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDALEIGTALYVQYAVDFLNK"
     gene            complement(15875..17062)
                     /locus_tag="PC366_000985"
     CDS             complement(15875..17062)
                     /locus_tag="PC366_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576524.1"
                     /translation="MEAITAFCLVLISLTIGDIVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTIVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTDEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVICLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIVGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            complement(17425..19125)
                     /locus_tag="PC366_000986"
     CDS             complement(17425..19125)
                     /locus_tag="PC366_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2576525.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIKDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPDGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            complement(19381..19656)
                     /locus_tag="PC366_000987"
     CDS             complement(19381..19656)
                     /locus_tag="PC366_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2576526.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIHAEVEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
     gene            complement(19775..20326)
                     /gene="mobB"
                     /locus_tag="PC366_000988"
     CDS             complement(19775..20326)
                     /gene="mobB"
                     /locus_tag="PC366_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HDF2576527.1"
                     /translation="MKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGYRVGVIKH
                     TCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKEKNPLYKMIQLYEDMDLI
                     IIEGYKNYRFKRLEVTRKGKYEDILSNKSDLIGIVSDIEYKLNIEQFNLNDYKNISKY
                     IESCIKNEILSISNVEIKNILKE"
     gene            complement(20331..21512)
                     /locus_tag="PC366_000989"
     CDS             complement(20331..21512)
                     /locus_tag="PC366_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HDF2576528.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKIVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGEVFNKVLNKNEAVKIMTGGKIPQGANC
                     VIKKEDVTVIGDMIILNVKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASLG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILELEKKVKNMLQSVDFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVGILGEKLLFGLSGNPHAAIVVFDNVIVPVIEYLTYKKGIHHIKAIFKGEFNKLSN
                     KDRFVSGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVEIVI
                     R"
     gene            complement(21723..22457)
                     /locus_tag="PC366_000990"
     CDS             complement(21723..22457)
                     /locus_tag="PC366_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576529.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINENKVVNVETNSFSSQGISVIDAESSVVIEKSDHEKSAVSLENFR
                     RIDLGEYVGVEESRINEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
     gene            22819..23724
                     /locus_tag="PC366_000991"
     CDS             22819..23724
                     /locus_tag="PC366_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2576530.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVSK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKGVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
     gene            complement(23884..24726)
                     /locus_tag="PC366_000992"
     CDS             complement(23884..24726)
                     /locus_tag="PC366_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2576531.1"
                     /translation="MTTSSKKLDTISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSSSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGIV"
     gene            complement(24710..25468)
                     /locus_tag="PC366_000993"
     CDS             complement(24710..25468)
                     /locus_tag="PC366_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2576532.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            complement(25485..25955)
                     /locus_tag="PC366_000994"
     CDS             complement(25485..25955)
                     /locus_tag="PC366_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2576533.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDELLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDIKMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            complement(25955..26698)
                     /locus_tag="PC366_000995"
     CDS             complement(25955..26698)
                     /locus_tag="PC366_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane biogenesis protein"
                     /protein_id="HDF2576534.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEITIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENDVEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLELGDMAIIGSYF
                     KDNYKDFGNVSVEHVKTFMDEIKKIREEL"
     gene            complement(26702..27115)
                     /locus_tag="PC366_000996"
     CDS             complement(26702..27115)
                     /locus_tag="PC366_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HDF2576535.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDIECEYIILSDLYGASVCTAMLRLTNLHNVKLFSGMNLNMVLELLTR
                     FSDELTVEDIEQLVEESRRGIQSVTLQIKEEEEVF"
     gene            complement(27141..27893)
                     /locus_tag="PC366_000997"
     CDS             complement(27141..27893)
                     /locus_tag="PC366_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2576536.1"
                     /translation="MDEKRQKKEMDLEVNSFVPLYQQLYDNIKKQIASGIYKPGDKLP
                     SEGDLCKEFNISRITVRNALNELVKEDILCKKRGKGTYVTIPERIEATCAGNSFTNSC
                     HRINAKPSTKIISVLIKKADKQVAEALSIELEEKVICIKRLRLIDEVPVIFEVDYFRI
                     DYMFLLKEELEDKSLMEVISNNISTLPKRVENIFEVKHSNKEYSDYLKCASNMPLLKV
                     RQSVYTENNDVLYYNEQFIRSDKYKYAVSAEI"
     gene            complement(28133..29527)
                     /locus_tag="PC366_000998"
     CDS             complement(28133..29527)
                     /locus_tag="PC366_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDF2576537.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSRNYMEFLSKSKTERLSV
                     KEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTALPLALHGIVILNDGTKVDIS
                     IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNIPLEDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGFDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKRI
                     FNKGNVVWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            complement(29547..29756)
                     /locus_tag="PC366_000999"
     CDS             complement(29547..29756)
                     /locus_tag="PC366_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HDF2576538.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            complement(29785..31230)
                     /locus_tag="PC366_001000"
     CDS             complement(29785..31230)
                     /locus_tag="PC366_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2576539.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSSNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESKDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTNKYKLSKNLINDKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISVISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            31340..32134
                     /locus_tag="PC366_001001"
     CDS             31340..32134
                     /locus_tag="PC366_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HDF2576540.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQSKYKDKISIKKGIEFGVQTQLMDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQYEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLKQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            32185..33507
                     /locus_tag="PC366_001002"
     CDS             32185..33507
                     /locus_tag="PC366_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDF2576541.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALIISIV
                     ASFNSSFLSLKFLKDAKLNLFILAVCPAIVIITLSNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGIVSG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPGLNIYAYIYTMTIVSIFTCLLHTIVLFKSLKSIR"
     gene            complement(33608..34825)
                     /gene="cdeC"
                     /locus_tag="PC366_001003"
     CDS             complement(33608..34825)
                     /gene="cdeC"
                     /locus_tag="PC366_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HDF2576542.1"
                     /translation="MQDYKKNKRRMMNQPMSTMNEEEVYTDEINSEDMRGFKKSHHHN
                     GCNTDNKCECHDECNPCNPCNPCKPNPCNPCKPNPCDDKCECHDKCKCDCEPCEMDSD
                     ECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGEPLTFE
                     TEVVEVFGSIPSAGQASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGRNCETT
                     FEFAVCGERNAECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALAFPAVR
                     AGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILKLECNE
                     CCEPFYELIIPNDIDLVLCLQETVSTLISEQIVVLASPNPIQPRLVDTFSKVCDFSQC
                     GPNHGSGKPSCHR"
     gene            complement(35008..35188)
                     /gene="ssrS"
                     /locus_tag="PC366_001004"
     ncRNA           complement(35008..35188)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="PC366_001004"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(35303..36208)
                     /locus_tag="PC366_001005"
     CDS             complement(35303..36208)
                     /locus_tag="PC366_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576543.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHGNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSRDERKILIKIESVL
                     DLVRGIKKLNNIDMVDTEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNDDEDNN
                     DELNYEDEELDCEDKELDDDELTDEGEMEDNEDELVEDKNTGYENIENDEDIVYDEEL
                     YNINEQESEYNYNEKNTKTRAKKKR"
     gene            36420..36818
                     /locus_tag="PC366_001006"
     CDS             36420..36818
                     /locus_tag="PC366_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576544.1"
                     /translation="MKKLDTESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDNIMEKISDAENQRDTKPAKTKKAKPTKGKS
                     NSPAPKNTPGGQQKKSKGLFKKTKKSNPHE"
     gene            complement(36941..37957)
                     /gene="ccpA"
                     /locus_tag="PC366_001007"
     CDS             complement(36941..37957)
                     /gene="ccpA"
                     /locus_tag="PC366_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HDF2576545.1"
                     /translation="MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIK
                     ETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANTYS
                     DKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
                     TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLI
                     KYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGF
                     NDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRESVT
                     ERKK"
     gene            complement(38210..38410)
                     /locus_tag="PC366_001008"
     CDS             complement(38210..38410)
                     /locus_tag="PC366_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576546.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFEDCWRDIDIMSWIPF
                     LILLLITCSCGGFFDGEVGCGC"
     gene            complement(38444..38623)
                     /locus_tag="PC366_001009"
     CDS             complement(38444..38623)
                     /locus_tag="PC366_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576547.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFGDSWAEFDIMAWIPF
                     LIVLLILCCCGGCLE"
     gene            complement(38805..39011)
                     /locus_tag="PC366_001010"
     CDS             complement(38805..39011)
                     /locus_tag="PC366_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576548.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            complement(39059..39484)
                     /locus_tag="PC366_001011"
     CDS             complement(39059..39484)
                     /locus_tag="PC366_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576549.1"
                     /translation="MKYVGLLLTSVGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            39656..39883
                     /gene="acpP"
                     /locus_tag="PC366_001012"
     CDS             39656..39883
                     /gene="acpP"
                     /locus_tag="PC366_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDF2576550.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            complement(40027..41031)
                     /locus_tag="PC366_001013"
     CDS             complement(40027..41031)
                     /locus_tag="PC366_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HDF2576551.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVSNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(41045..41947)
                     /locus_tag="PC366_001014"
     CDS             complement(41045..41947)
                     /locus_tag="PC366_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDF2576552.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKKEK
                     SVLVNGVYKKPSLKVYSGDLIEVKIDEEKANFEPQDLNLQIIYDDFDIIMVNKPPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEELINRQALHAYKLEFEQP
                     RTKEKLKFKADIPEDMKELISKLR"
     gene            complement(42142..43317)
                     /locus_tag="PC366_001015"
     CDS             complement(42142..43317)
                     /locus_tag="PC366_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HDF2576553.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR"
     gene            complement(43404..44249)
                     /locus_tag="PC366_001016"
     CDS             complement(43404..44249)
                     /locus_tag="PC366_001016"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HDF2576554.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            complement(44347..45144)
                     /locus_tag="PC366_001017"
     CDS             complement(44347..45144)
                     /locus_tag="PC366_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HDF2576555.1"
                     /translation="MSTSDVKVYENVAVEVDGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            complement(45163..46173)
                     /locus_tag="PC366_001018"
     CDS             complement(45163..46173)
                     /locus_tag="PC366_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF2576556.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVQVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            complement(46192..46974)
                     /locus_tag="PC366_001019"
     CDS             complement(46192..46974)
                     /locus_tag="PC366_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF2576557.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            complement(47033..48169)
                     /locus_tag="PC366_001020"
     CDS             complement(47033..48169)
                     /locus_tag="PC366_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HDF2576558.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLKPLASGDKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            complement(48877..49344)
                     /locus_tag="PC366_001021"
     CDS             complement(48877..49344)
                     /locus_tag="PC366_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HDF2576559.1"
                     /translation="MSISNVREYFKQFGKEDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLTPEEVLEFTGHAIGGVCPFG
                     LKNSIKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKSEKWVDVCKNW"
     gene            complement(49423..49965)
                     /locus_tag="PC366_001022"
     CDS             complement(49423..49965)
                     /locus_tag="PC366_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576560.1"
                     /translation="MKKFIKVSFFILGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDIGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGMNKCSAYVNVDLF
                     NEKNSITESTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYIVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            complement(50017..50703)
                     /locus_tag="PC366_001023"
     CDS             complement(50017..50703)
                     /locus_tag="PC366_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDF2576561.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLLSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGFIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDIANTKYINLYSMTFLTIIIFIISMYFSI
                     KISKKNKFNY"
     gene            complement(50691..51563)
                     /locus_tag="PC366_001024"
     CDS             complement(50691..51563)
                     /locus_tag="PC366_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2576562.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     NFDREKFDEYLNKFDIEENMHIENLSKGQSEKLMLSSALSHNAKLLILDEPTAGIDPI
                     VRTEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVRGCSI"
     gene            51698..52498
                     /locus_tag="PC366_001025"
     CDS             51698..52498
                     /locus_tag="PC366_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HDF2576563.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            52523..53092
                     /gene="yfcE"
                     /locus_tag="PC366_001026"
     CDS             52523..53092
                     /gene="yfcE"
                     /locus_tag="PC366_001026"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HDF2576564.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIETLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFGEIRIILNHG
                     YIESEEEIIDKAKKMGGDILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
BASE COUNT        17310 a         9418 c         5580 g        20991 t
ORIGIN      
        1 gtatctagct atcttaaagg ctaagatgat agaaggatta tacctaccat tttctaatga
       61 acctatagtt tgtcttgata cttgcaaaat agaagcaagt tcttcttgtt ttatgcctct
      121 ttcttttctt atttcttcta atctattttt cacatctatc cccctttaat atctcaacta
      181 cggaaagtct actttccata attatacaac tatatttcat ttatgtaaag cttgctttcc
      241 atatttacaa aaaaataaca gactattttc agcctgtaat tttaaaattt catgttgttt
      301 attaaattta atgttattca ttaactttaa cttggtttct gaattggaat ccaaacttct
      361 gtagtataat caggagcatt gatatcgcca ttgggataaa gttcaatatc tggtaagtta
      421 gcatacacat acccagaact tggtaaccac tcagtaataa ttcttttttg caattcctgt
      481 attgccagag catttggcat tggagaaaca cattcaaata ctgcccatgt acctgatggt
      541 attaagtatt cacgagtatc ttctaataca ggcttatctg ttggtgcagc aatataataa
      601 tctaaaccct tactatttgt acacacacta actccaagca atccacaagg ttcgttattt
      661 attaactctg aaagtttatc aattgttcca ttttttatgc atttagccca taacttagga
      721 actttctcaa agcactcttc tacaatcatg ttcatacttt cttttatacc aacaatacga
      781 aaccctttct tttctacaat acgatattgc atttctacat ttccttttac ataaatgctt
      841 aatgtcatct taggatatgc ttttaaaaca acaccctttg ctctagctgc agatggagaa
      901 atgttatgta tattttgaaa agctctatta aaagatgttg gtgaatcgta accatacttc
      961 tcagatagtt ctaaaatttt gatgttactg ttctgaagtt caaatgcagc cttagtcata
     1021 cgtcttcgtc taatatattc agataatggt acttctgcaa tatatgaaaa cattctttga
     1081 aaatgaaagg ttgaacaaca tgcaattttt gctgcttctg cataatccac tccactttcg
     1141 agattttctt caatataagt aatagcttga tttaatttat ttatccattc catttgatat
     1201 tacctccaag caaattatac agtttaataa aataatatac ctctctattc atgcacaaaa
     1261 ttgtaagcat ttaaattcat aagtattttt caatcaatac aataaatata aaaattgtat
     1321 tatacaataa aaaagttcaa taacatttta ttataaaata ttattgaact ttttataaaa
     1381 attaatttaa gtgtagttaa attaagtatt aaactatctt atatattaca atatcctact
     1441 atcttatagt cttctggcac tttataatct ttgtctggag tacctaaatt ccattttaaa
     1501 tcaaacatag ttgcacttat tattgttgca aaataaagca taactatacc aatgtctatt
     1561 ttttcttcat ataaattagt atgaccatct tttctaacag ctaaaactac agtgcctcca
     1621 tcaactataa atctccatgg ttgtctattt aatgtagatg gagctaatct tgcatagtga
     1681 aatgcatcaa gaagtgctct ttcttctaag atttctatac ttgcaacatt tccccattcg
     1741 ttcatataaa caacatcttc tacacctagt ctagtagacc ccttatctgt tacaacttgc
     1801 atatcagatt ttgaataatt ttgcccagtt tttgtagcat ttaatacttt agcattactt
     1861 acattttctc catatccaat agctataatt cctgttacct ctttatctga attaattcca
     1921 agtttttctt ttaccttttt tccatcttca aaagtaaccc aacaagaacc aattccaagt
     1981 tctgttactt taaagattat actttctcct atgtaccctg aattttcaat gtaattatct
     2041 tttatgtcag ataatattat aatataactt ggagaatcta tcatatttcc tttgtaccct
     2101 gctactttat ctaaattatt aaaaacttca cttttattca taattcttac atcaacatct
     2161 atttctggaa ctagtttctt acaagattct gagtatttct taatttcact aagatattct
     2221 tctttaatat ctatgttctt atattctcta acagactttc tatttaatat gattgtttta
     2281 taatccataa ttttatcctc cccaaactag tattgtctta attatatacc cattaatata
     2341 ttattttact catttattta ataaataaag attacaattt tgtaattatt atttattaat
     2401 aatattccac ttttacatta ataatgacca gttgtgcaaa atccattgcc aaccaccaaa
     2461 taaaaacata ttataaaagt aatataaaat aacaaacaaa tcttaacaaa aaattaaact
     2521 ttttttacac gaaagaaggc ttcccgttgc cttctttatt tttataaaaa aataagctgt
     2581 ttctaaaatg atttcacatt tttgaaacag ccaagttatt ctataatgac aactataatt
     2641 tgaggatgtg agggagagtt gtcattataa atttagggta attatattat gttttaagct
     2701 agttcttcct atatttatat aatacatttt atatatgaat tttatatgag attggtataa
     2761 atgatatatg aaattacata tgtttatatt atattaaatt ttattattac attttccaca
     2821 acaatactca tatgtctcca cattatttgg aatatttaca aatacaaatt ctttacagtt
     2881 ctcacaatac tttaatatag atatagttcc acaagtgtaa cattcaaata ttacacaatc
     2941 ctcattttcc tctactattt caaacttttt actatgttca ccacactctg ggcacttgtg
     3001 attatttaca ttcataaata ctcctcctta ttagtatagt tacatttcaa aaacttaatt
     3061 aatgtattct atattactta ttatatattc tataataaat catattctaa tataataaaa
     3121 caaattaaat aaaaaaaaac cataaatttt aaatttatgg attaattctt gtaatgataa
     3181 ctctatttga ggatgtgagg gagggttatc attacaatag ggtattatat tatggttttt
     3241 aagctagtct ttctacacct catatgatac atatgctata tgaattttat atgattttta
     3301 cataaatatt ttatgaaatt taaatttttt agtcattttg aaatttgtaa aaagttctct
     3361 aaaaatccac agcatcataa acagccaaaa tttaagtaaa acatcataaa aaaatttgtc
     3421 caataatttt aacaagtcat ttcacctcat tataattatt gacacaaact taaataaaca
     3481 atctataaat cttatataaa tcttaaactt tacccttatt gatacacaat ttctagtttg
     3541 tcaattttat tttgcatctc taagaaaatt tcttcaacag aattgttaaa tatattgcct
     3601 aaatagactc ttttatcttt ttgaaatgaa taagatttta cactaccatc agaagaaata
     3661 tataaatgac tccactctgc tccatatttt gaaaacctct cctttgtatc tttaaacctc
     3721 atatcttcta tttttattgc tttttctctg tctcctctta ctacagtgtg accccttttt
     3781 attaaactgg ttatttttat atcttctttt aatttaatac gtgtatcatc attttttgaa
     3841 tatactttcc atatcacttt atgacgataa ttatctaatt cttttattaa gcttctatca
     3901 atagtaaagc tatctttagt taccacaatt aaatcaaaat ggtctaacat atattgaaat
     3961 atttctctca tacttttatt ttttaaaata tcctcaccaa taacctctat aaatctacag
     4021 cctttctcat acatgcagtt caataaactt gtgatttcag aaaaataatc atttgtatta
     4081 ttatctccat ctatttctat agtaaagtac aaaggagtaa tgtatgattt atttcctgtt
     4141 atctcaaata cacttgatag tgtctgtata tcatcttcaa acgttaagta tacattctca
     4201 taaaacataa aaaattccat aactttttct ttcatattat ggatatttct atatctattg
     4261 gataatatat ttattatatc gtcagtagta tttttcccat cacattcagc cagtataaca
     4321 atttgcttcc aacttaagct atccacattt ccgatacttt ttttatatcc atcttcttca
     4381 tcataaatag gaccaattat aatgttttct tttggccaca gatgaaccct agttccatct
     4441 tttaatttcg gatatttatt ttttacagac tcataaaatc tacttgtatc acccatgatt
     4501 ctttactccc ccccatagtt taaatattct atgctaaaaa tagcacttta tttttattaa
     4561 ttcaacaatt attcaaaatt ggtcattata tatgtttaaa tggatttaac atcaacctta
     4621 tttatatgtt attgatgttt atatatgtta tataaaatct tatttctcat acttcaatgt
     4681 aatcttaact atctctggtt tacaattaag cctaattaaa acttttgagc ctcctaagcc
     4741 tttatttaaa atcatagtgc tattatcttt ttcatatttt ccccagtcat acttaggaaa
     4801 gaactctcta tttggagata atacacctcc aacaaaaggt attcttatta tacctccatg
     4861 aacatgtcct gctaaaacca aatctgctcc ccattttgca tatttttcaa agaaaaatgg
     4921 tgtatgtgct aaaagaatgt tatattcatt ttcattaact ttacctagat tgtcttctac
     4981 aaaattgtca cttagttcta attttttgtt attagcaaat aaatatggat agcattccaa
     5041 tggtataatt aaaccatata aattaagatg gctattacct ctatatattc ttacagattc
     5101 attttccata tttattattt tctttgaata tagttcctta aaataatcct tatatagatg
     5161 tttatacttt tttattaaag atttttgttc atgatttcca attatatgat atacttcata
     5221 tttttcaacc aaattatcta ttaaatctaa tgcaacttga aaatttttat tttctccatc
     5281 tactaaatct cctgttataa atataacatc tgggtttaat gattcaattt tatctatcaa
     5341 taccttatta tttttatcaa acaccttatt atgtaaatca ctcacttgaa ctattttaaa
     5401 gttatcaaat tcctttggaa tttttttgtt gaaaatagta tattctgtcg tttctatatg
     5461 ctgagtttca tacttataca gaatatacaa taatattaat actaatactg tcattgaaac
     5521 ctttataatc atattctctt cctctttatt ctattttgtt aatattatta taatgctttt
     5581 atgttttttt taaaacaata acatcatcac atacatataa atcttttcga cattataaaa
     5641 ataagttatc cttttctaaa attttcattt attttagaaa aggataacta taaaattatc
     5701 tataaacctc tatattgtga aatatagttt ttcctttatt taaattttta tatatatgct
     5761 ctaaagttcc atcaaaccta atagaatgtc cagactctaa aatataagtt ttcccatcca
     5821 cattaaggtc aagtttacct tctattacga gtacatactc ttctaaaaca taactatgtg
     5881 tagatgaaac atgagtacag ttttcctcaa gctcaattat aaaaagttca aaccttcttt
     5941 gagggctaaa agggtatatt ggatataact tcatgttccc tttttgctca acaataggct
     6001 ctacttcttc tttctttata acctcatagg tatttgtatt ttcatttaat agtgtagtaa
     6061 aatttatttt aaatccagat gaaattttcc ataaagtaga tactgtcgga cttgattcac
     6121 ctctctcaat ctgtccaagc attgctttac tgacacctgt catctttgaa gctttgtcta
     6181 aacttatgcc catttcttgt ctcaataacc ttaaattttc tcccacatta ggaaatttat
     6241 tatccatgtt aaaatcctcc tgatagctat ttgtattcta tgatttttac tcctgtaagt
     6301 tctactatct cttttaattt taacatatga ttgttacaaa tttcatcaaa ttcatatata
     6361 taatcttcaa gccctaatgc cttatattta tcgattccaa atttatgata tggaagtaac
     6421 tccatcttgc ctcctggaac attttgtttg acaaataatg cagtatttct tatattttct
     6481 tcactatcat ttactccata aataattggc actcttataa ccatagattt attcaacttt
     6541 gaaagcctac atatattatc taatataatt ttattactta ctcctgtata ttctttatga
     6601 atattatcat ccatagattt tatatctaca aatatgtggt ctattttctc aaatacatca
     6661 tttaccttat tccaatcaaa atatccacaa gtttcaattg caatatttat gcctttatca
     6721 taaaaaatat caactaattc tcttaaaaaa tcaatctgaa gtgtaggttc acctccagaa
     6781 aaagttatcc ctccattaga ttcaaagaaa aatataaaat ccttttcaac ttcctctact
     6841 atttcttcaa cactcatttt ttcggtcatt atacaaatgg catctttaag acataccttg
     6901 atacactctc cacataaatc acatttatta tttatttgcg ttctatcaaa tagtgaactt
     6961 atattttgag gacaaacatc tatacatcta ttacaggata cacatttatc tttcataaca
     7021 cctaatttta ctatgttact ccaggaatct ggattagaac accacttaca ttttaattta
     7081 catccttcta aaaatatagt agtccttatt ccatctccat catttactga aaaatgttgt
     7141 acttttacaa ctctaccttt tttactcata atctacctca taattaaaaa ttgctatgtg
     7201 aatttctagc tattatagca tcttgcattt ctcttgataa attaacaaat tgagtactat
     7261 atccagcaac tctcactaat aaatctttat attcttctgg attttcttga gcttttaata
     7321 gagtatcatt tgatatcgta ttaaattgta catggaatcc tcctaaagca aaatatgatt
     7381 taatcataga tgttagattt ctaagtcctc tttcagtttc caccaaatct tgattcagtc
     7441 ttaaatttag aagtgttcca ccagtatgaa catcatgatt tatttttgat gcagatttca
     7501 tggctgctag tggacttgtt gtatcagtac caacaaacgg agaaactccc tctgtcaaag
     7561 gttttgtcgc ttttcttcca caaggagttg cacctacgat ttttccagtt ggtacatagt
     7621 ttgatatacc cataaatgca ctattaaatt tagagccaaa aatatccttg tattttctag
     7681 tttcagtata ataaaaatca gaaacttcaa ttgctaatga atctacataa tcattatcat
     7741 ttccatactt aggaacatcc aacgcaagtt ttcttaattc ttcataacct tcccaatcat
     7801 tatttagtgc ttttgttaat tcttctagcg tagtcacctt atcctcaaat actaattttt
     7861 ttatagctgc caatgaattt gaaactacac ctaaccctat accagttaat acaggaccta
     7921 tattatattt tgctcctcct ttacttaaat caactccctt atccaaacat ccatctacac
     7981 aagtagataa aaatggtctt ggtaccattt ctttatgaat ttgttgagca acagtagttc
     8041 ctataacaga actttttaca agatatgcta attgctttaa aaactcatcc ttaagttctt
     8101 caaaagaagt aaattctgtg atattttttg tatctaaccc cattttttct ccagttaatc
     8161 tactcttacc ttcattcata gcatattcta aagctgctgc aaaattgata tttacggctg
     8221 aagtccactg tcctgttttt ctaaaatgag gaactacaca accacagtta ctccaatctc
     8281 tagcatcttc tgcatcatat ccatcttgta ataacatttg tgcccctgca ctatcgctgt
     8341 gtatagcagg gaaaccagtt ccttgtttta ccaatttagc aactgccatt acgaaattat
     8401 ctggtgctcc ttgactcact ctaacactta atcctggctg gtgagttttt acactttctg
     8461 tagcctttaa acacatatat gagatatcat tcgttccatc agtaccattt ctctttttac
     8521 caccaacagt aagattttgg aattgattat atcctgcaaa gtaatttgct gtatttgctg
     8581 atatagtcca tacccattct gataacttaa tccaaagtgc ttctatcaat tcttgagctt
     8641 ctgattcagt tattttacct tctctagcat cattttcata atatggatac atatattggt
     8701 caaatctacc taaatttaat gccaatggat tttctgatag aataccacct aattgaacaa
     8761 accatacaaa ttgtattgct tcataaaaat tagttggagg gtttgctggt acattcatac
     8821 atatctctga aatttttata agttctaact ttctcttttc atctgtttct tgcttactca
     8881 tctcttttgc aagatttgaa tatctttgtg ccaatgtcat aataccctct gcaactatag
     8941 aaacagattt gtaaaaatct atcttttcaa tattttctga aactgatata tctaattctt
     9001 taattttttt atctgcatct tccttaatcc ctttatatcc ttttacaaac aatatatctt
     9061 gataatctgg tgttacttca ccaactgcct gtctccactt agaatcatta tctattattc
     9121 ctgtatctac taatatctta gctgtatctt ctgggattct tgctaagaaa acttcttcca
     9181 aagattttcc cttccaatat ggaaatattt cttttcttat aaattctatt tgttcttttg
     9241 atattacata tgggtcttga gttcttttat caaaagtatc catttctttg tctacccatt
     9301 gccaagaaaa ctctggtgtc aatatccctg ttcttctaaa ttttcctgct gtacctacta
     9361 ttaattcatt ttcaaagatt tttataggaa gttctttaca tgtctccaaa aaagctttag
     9421 ctcttcttat acagatagct tctccctcag tttttttatg tgattctgta aaaattctag
     9481 ccctttcaca acatatcata ggtttagaat taatatattc ttgtctaaat gcttctattc
     9541 tattagtttg actcatttaa aatccccctt tggataatat atactacatt tttgtatgtt
     9601 ataacatact ttaattatat tatactgtcc tttagcataa aatggaagca aaataacttt
     9661 ttttttcatc taccttgaac acctatatat taatactttt tttgttaaat ttataaaatc
     9721 taaaaaaatt ttctatgata tattttctat attgttatag ttatttctaa tatactaatg
     9781 atttgaaata tcaaatttgt atactagact tagttttaaa accttagttg attgtttaac
     9841 tttgttaact tcaacatgta tatccttcat ataaggaagc tccacaacac ctactccctt
     9901 attaaattct tcttcaacca tagaaaaaat ttctttctca gttaagttcg tattagtcaa
     9961 tgatttaaat aaattgtata taaatttaat atatttatca ctctcagata acttatcatc
    10021 ttctggatac tctttagcac agagaatatc tattgttact tttccttctt tatcgtcttc
    10081 agacatagaa tagaataaac ttcgaatatt tttttcaggt ggtttttcag caccatttat
    10141 agatactaca aagctaccat ctgattttga gtcagtaata ctataaccac tgtctattat
    10201 agctttcgaa aatctttgag ataaatcttt ttttacttct tctctacctt tcgcatcatt
    10261 aatcttttgt gagtaattat taaatagctc gatagattca tcttttttat cttcaacttg
    10321 ttctttcaat gaatctttac taatttgttc tgagctactt aagttcttat cagatacagg
    10381 agacatacat cctgccatca atgctaagct aagatttaaa gccacaatta ttgccactct
    10441 atttatattc ctttttactt tcatacacaa tcctcccatc acactaaccg ctctaaagta
    10501 ttattcattg cattagaata tatttatatt ttctttatat taaagattta ttattcaata
    10561 catatcacct tcctatccaa ttcttataac ttactattag taaaattata agctccttaa
    10621 tacagaaata aggatgttat cttttgttat taaaagataa catccttatt tttttgtatc
    10681 aatacatatg tcccaactgg taacttaatc gccccaactg tcagtatctt gctccaatgg
    10741 tatatatata tttagtataa atttatcgat actattttca aataataatt ctccattata
    10801 tttttgtaaa gaagatttaa tactctgaat acctattcca tgtacgaact tatccatttt
    10861 gtttgttaac aatatatttt tattaaaagt aagctgattt agtttactat tttcacattt
    10921 aagtacaaaa aatgactttg ttatagttcc tttaattcta atatatttat taatattttc
    10981 atccactatt ttatcacatg cttctattgc attatccaaa atattagaaa atatgcttga
    11041 cacatctata ggttttacaa aatttacttt tgaaaaattt atagagcaag taaatttaat
    11101 tccttttttt aaacatattt cactcttttc gttgattata atgtctaata tcatatttcc
    11161 tgtattatag atatatttaa atgtttttat ttcatctttt aaattgttaa catattcatt
    11221 aatttctttg ctattgtttc taaggttgtc tatacaataa atgtggttat ttatatcgtg
    11281 atatagtttc ttaactcgca tatgagattc ttgaatactt aaataatgcg catattgcat
    11341 atctaactta ttttttatta attcagcttg agattttaat ctattctctt ttattatttc
    11401 tttaaacaat aatataagaa atatactact agctcctacc aactttggat taacaaaatt
    11461 atcaaaatag tatccttctg aatgtaatga cccaaaccgt tctaattttt ttaatacata
    11521 atttacaagc atattcattg tattagctaa taaggcaaat aataaatata cataatttct
    11581 cttatcttgg ctaattaatt ttatagactt cctaaaaaag ctaaatacaa gatatataag
    11641 aataattatt aaattactat atatctgaat ttttatagat tctaagtgag gtactaataa
    11701 ggattcttta gatgaaataa cattacctgt aattgcaaaa aatagtattc tatatataac
    11761 agcatccaaa catttataat atacactaaa tagataaaag aaaatggaat acttaatata
    11821 atccatctta taaaaataat tatagtatcc tccccaagca ataaatgcta atatataaaa
    11881 taaatagttt atattactaa agtaacttcc tccattaaat aatctactta tctgaattat
    11941 aatataaata agaaacaaga caatatagaa tactattttt tcattttttt tactatcctt
    12001 tttataaatt aaaattccgt tcattataga aaactgtata aatatagata aaactactaa
    12061 tagctcattc ataaaattta gcatattgta tcaccaagaa attttaaaaa tttctcctta
    12121 acttctttat atctatatct actaataggt acctcttctc cactttccag tattgcagca
    12181 ttaggcttta tattttcaac atatcttaaa tttactataa aacttttatg gcatcttata
    12241 aatttatatg gatttaattc tttttctatt ttacctaaac tatattttat atcaaaattc
    12301 ttgtttattg tgtgtattag catatctttt ttttgaactt ctatatattt tatttcattt
    12361 aaataaatct tatatgtatt agacttattt tttattgtaa tatgactttc cttatttatt
    12421 tcaatatctt tgatacaagt tagcacatgt ttttttagtt cttccaactc tattggcttt
    12481 agtaaatacc tataagctct tacctcataa ccttcttgca cataatctat taatgaagtt
    12541 acaaatatta tttccatttc atcgtctact tctctaatct ttcttgcagt atccattcca
    12601 tttaattttt ccatttttat atcaagaagt aatatatcta tatcttttaa attactttcc
    12661 agtaactctt ctccagatat atacttttgt atctcatatt ctatacttat atcttttaat
    12721 atattctcaa ggtaatcttc tattaaaagt tgtgtttctt tttcatcttc acaaactgct
    12781 atcttaatca taaaatgcct ccttacataa tttctagtta atacaattaa aatatttata
    12841 atatatttaa agataatttt gtatatctga tactttagga taacattttt aaattatttt
    12901 tatcaatact caatccaata caactattat ttgatatttc aatttaaaga cagaaattac
    12961 tataattaaa aacagtactt tactaacaaa agaagatgtc ttaaaatatt aaaaaaataa
    13021 ttttaggaca ccttctttta tttatttaaa ctttttaagc cttaaataat acattaatct
    13081 cctatataat tgtactgcat ataaaatcaa caatataatc tgtagtacaa tagcagttac
    13141 agatgctcca taaccactat ataaatttct tatttcaata ttcaataaat atataaatat
    13201 tactactaac ataaagaata taaacatatt cataaataaa attgacttta ctttgttttt
    13261 tttatcagaa tcactatata atttaggagg tatgtctttg tattctttcg accatatata
    13321 ccatgcagat gtacccataa aactaccaat actcctaaat acaagattcc agccatttga
    13381 tttatgttca tcaaaataat tattctctac atcatagtag taatcaacag tgtattttat
    13441 ttttcttgga cttcccttat gaaaataaaa tattcctcca aatttattta tcttatataa
    13501 attatatcct ttagcttcaa tatcttctaa ccatttctct atcttatcag gtgaactata
    13561 ccagtcaaat ttgaatttta ttttcttttc catagcactc attctccaaa atgatatttt
    13621 taaatagctt aaaaatctat ttaaataatt atatcatttt gatactaatt ttaggttaca
    13681 atcatatatt taaaaagcta tttaaatagt aataaactaa tagccataac acccattcct
    13741 gcaatcaatc cataaataga taaatgatgt tccccgtact ctctagctga tggcaataat
    13801 tcatctagtg atatgaatac cataattcct cctacaattg caaatacaat tccaagagtt
    13861 atatcattta aaaaatttct aagaagtaca tatccaataa tcgctcctaa aggctcagac
    13921 ataccagata aaaaggaata ataaaaagct ttctttttat ctcctgtggc ataataaact
    13981 ggtacagata cagatatacc ttctggtata ttgtgtattg caattgcaat tgctatcggg
    14041 atagctattg taacatcatc aagagctgat ataaatgtag ctaatccttc aggaaaattg
    14101 tgaattgcta tagccattgc tgtaaatata cctgttctca aaagagactt attttttttg
    14161 atattctttt cttctatatt ctccattttc tttatttcat gtggattttc ttcttgtgga
    14221 attaacttat caataacagc aatgatagcc atacctataa aaaaagctat tacagttgac
    14281 caacttccta atttctctcc catagatttt gtcaaagcat cttgtgcttt aggaaaaatt
    14341 tctatcatag aaacataaat cataacacca gcagaaaatc ctaagcttat agaaagaaac
    14401 ttagtatttg tttttttagc aaaaaatgct atacaacttc ctataccagt agataaacca
    14461 gccaataatg ttatcaaaaa tgcaaatatt acattattca aataaatcac cttcttttta
    14521 attgatattg attatcattt tctttatgct atcatatata ttttatatag tcaatattta
    14581 taaaaaatat acacaataaa aaagcagaga tataaactta gtctctgctt tttctttata
    14641 gtatattaaa attatttatt taagaaatcc actgcatatt gcacatataa agcagttcca
    14701 atttctagag catcttcgtc tatattaaag catccatgat gatgaggata gcaagcacct
    14761 tttgactcat ttctagctcc tacaaatgct agtgcaccag gtgctatatt cataaactca
    14821 gctaaatctt ctgctcctgt tactttttca aatagtgtta tacagtcttc tccaaatagc
    14881 ttaattgctg catctgtagc tatctttgaa cattctttgt catttataac tgctggtgtt
    14941 aagtacccat actctaattc agcatctgct ctatatgctt ctgctgtaga ttttgctata
    15001 cgttctaaaa ttccaggaat ttgctttcta agctctggat taaatagcct tattgtacct
    15061 tctaagacag cttcactcgc aattacgtta aatctagttc cagaatttaa aactccaaca
    15121 ctcacaacta atggttccag aggacttact tctctactaa ccatagattg tagattcata
    15181 actattgctg aacttgcaag cactgcatca acaccttgat gaggaagtga accatgacca
    15241 cctctacctt ttacagtaat tttaaagaaa tcggcagaag ccattcttgg tccttcttct
    15301 accgatatag tcccagattc tacatcagtc caaagatgta ttccaaacac actatctaca
    15361 ccttccatag caccatcttg aatcatagct cttgcacctt taccaacttc ttctcctggc
    15421 tgaaaaaata attttacagt tccattgata ctatccttaa tatcatttaa cacttttgct
    15481 gcccctagaa gcattgatgt gtgaccatca tgaccacaag catgcataag tccttcattt
    15541 ttagatttgt attctacatc agtgcattca acaacttgta gagcatccat atcaccccta
    15601 agtgctacag tctttcctgg attagctcct tttatagttg caattacacc tgtacctcca
    15661 gctgatacat atggtatctc tattttatca agttcttctt taactctctt tgatgttcta
    15721 acttcttcca tacttttctc aggattttca tgaaattccc ttctaagctt aattacatag
    15781 tctttataac tctttgttat ttctttaata tccattccat acctccaagt agtacacatt
    15841 cttcttattt aaaatacttt ttatcactta aatactatat tagatttaca aagatacctg
    15901 ctattactac agaagctatt gtaactgtag taaatcctcc aacaagcatc tttggaagca
    15961 tcttatccat taaaaattct ttttcttctg gtgtttcagc caaagccttt actgcctctt
    16021 cagttaatat atagtttggt ggaaaaccat aaagtgatgt aagcgaaact gaaaaagcca
    16081 tttctttact ttcacctaaa agcttaccta ctataataga gaatattccc atacctatta
    16141 caccaaatat tatgattcct acaagaggaa ctgccatttc aacaagcatt gctggtgtag
    16201 cttttgctaa tcctgcaaat ataaaagcca tcaatgatgt cattaaccat ccaaatgaac
    16261 cagatttatt aagtggtttt ctatcaacta ttccaagttc tgatgctatt acaccaaata
    16321 ttaaacatat aacatatctt gatacaactt catttgtaag atttgtaaat tgtactgcta
    16381 accatgctac aaatcctaat ctaagtatta tcatatatgt cgtatcatat ttttctggta
    16441 agtctggaat tatcttaaat ctgctttttt gttcaggtaa atccttaact ttttcttcat
    16501 ctgtatttac agttactttt ccacttctaa agtctgataa aagtcttttt ccttcttttt
    16561 taagcattaa tgctgtaata ggataacccg caaatccttg tgcaacatac atcaaaattg
    16621 caagtactga taaacttgca agaccttttg ctgtagcagc atctgccatc attatagatg
    16681 caactagccc tccagtaaga ggaggtgtag ctattactgc tgtatcccat ccaaatacta
    16741 ttgtccctaa tgccaaagca cctacacata ttcctactat tcctgccaag gctattacta
    16801 ttgttttcca ttgacctgct aattccttaa tactcatcat agttcccata tgagttatta
    16861 acaaaagcat acctaattga gctaatggtg ttcctaaagc ggctaagtcc acaatatttt
    16921 ctgggaaaaa agtccagaat cctactataa atataattgc tgatacaaaa accgacggaa
    16981 caaaagcttt agtttttgct gaaactatat ctcctatcgt cagtgatatt aaaactagac
    17041 aaaaagctgt tattgcctcc atacaaaatc ccccctcata ataaatgtat ttttataaaa
    17101 tgtatgtata gttatccatt attttactac ttttgaaaaa catttcaagt caaaattcga
    17161 tttttttcat aaaattcgat aaattccata aattaaagtt agttttctaa attattcttt
    17221 ttgtaaaaac gttatcctga ccattggcta tttaactcta ttcttacaaa gagaattaaa
    17281 tgtaatttgc aaaaaataaa acataggata cattttattc ataaaacatc tcataaatat
    17341 aaaatgaatt gtctttatga atcttaatat atcctatgtt tgtaagttta atgcgtatgt
    17401 tagctatggt gtaaaatttg tatactagtt attgtgtaac ctactatata ctccattttt
    17461 gtttactaac tcttcatgag tacctctttc ttcaattcct ttatccgtca atactatgat
    17521 ttcatcagca ttttttatag tagtcaatct atgtgcaaca actaaatttg ttctatcttt
    17581 acttaattcc tctaaagact cttgaatttc tctttctgtt acattgtcta aagcagatgt
    17641 agcctcatcc aatattatta ttggaggatt ctttaaaaag attcttgaaa ttgaaattct
    17701 ttgtttttgc ccacctgata attttacgcc tctttctcct atataagtat catatccatc
    17761 tggcaaagtc tctacaaagt catgtattct agctttttta gcagcagcta tcatttcttc
    17821 atctgtagca ttagggttcc cacaaagaat attatctctt atagttcctg taaataaaaa
    17881 tacatcttgt tgaactatac ctatattttt tctcaatgat tttaaactaa catcttttat
    17941 actctttcca tcaattttta tatcaccctt atcaaattca taaaatcttg gcaatagatt
    18001 acataatgta gtctttcctc ctccagaagg tccaactaat gctatagtct taccagcttt
    18061 tatagataaa cttaaattat ccaaaacttg agtcttatct tcatatgtga aagatatatt
    18121 ttctatctca atgtcacctt ttacattttc aagttcaata ggatttttag cttctttttg
    18181 atggtcttgt tccattatct ctatgaatct tttaaaacct gtcataccat tttgatattg
    18241 ctctgtaaaa tttattaatt ttttcatagg ttgtataaac atttttacat atagtatata
    18301 agcagcaaaa tcacccaaag taatttttcc tatataagta aaataaccac cagctattac
    18361 aactacccac tctaagatat ccatgtataa attcatacca gagtaatatt ctgccattac
    18421 cttataagaa tcttgtcttg ctcttctaaa taatttattg cttcttacaa acttatttaa
    18481 ctcttctttc tcagtacaaa aagacttagt tactttcata cctgctatac tattttctaa
    18541 agtagcattt acatcaccta tagtaactct actcttcata aaagcaatat tcatcttatc
    18601 ttttttagct attgcaaacc aaattataaa cggtaatata gcaaatatta taagcgtaag
    18661 aggaatattt atatctataa gtataaagaa tgaaccaacc aacattacta tagaaatgaa
    18721 taaatcttca ggaccatgat gtgcaagttc tgttatatcc attaaatcat ttactattct
    18781 agacatagtt actccagatt tgttattatc aaaatacgta tttggaagtc tttgtaagtg
    18841 tgtaaatacc tcatttctca tatcagcttg catatctaca ccaataacat gtccccaata
    18901 ctgcataaaa tagttaagcc ctgcttttgc tataaatata agtataagtg ctactgcaaa
    18961 aactactaac attcttaagt ttttatttgg aacaacgtca tccattatat ttctagttat
    19021 cataggataa actaaatcac ataaggaaaa tagaaaagct gctataaggt ctagtgtaaa
    19081 aattttctta tatggcttat aatatttgac aaattgtttt atcataagta ttaaatccct
    19141 cctttattag tacttctata tagtacttct aaaaaatacc cataaattag tataacataa
    19201 caataacttt aaatctttta taaacttaca aagtaataac aatctttttc ataaaattga
    19261 agatttatat catatagttg tatacttgaa acagcataaa aagagctata tctctatatt
    19321 taaaatttta taaagataca actctatatt taatactaaa ttttttttat aaacacaaaa
    19381 ctacttcaat gcatttaata tctttttatc taatgctgtt gtatttatac ctgttatata
    19441 tcctgttgcc tttattgtag gtatatcata agttgttggt agtatagtag tagatacgat
    19501 taaatcagca ccttcttgtt ttgttgaaca ttcagcaatt ttacattgct caacttctgc
    19561 gtgtatatta ttttctttaa ccaatctttc tactctgtca caaactattg ttgatgttgc
    19621 gattcctgct ccacatgcta ctaatatttt tttcatatat tgtcctccta caatttcttt
    19681 aatattttat aactcaaaat aaaattgata aatttcttat atctttattt atataaataa
    19741 ttatatcatt ttatataaga agaacatctt aaaattattc ttttaatatg ttttttattt
    19801 caacattgct tatacttaaa atttcatttt ttatacaaga ctctatgtac tttgatatat
    19861 ttttataatc atttaaatta aactgttcaa tattcaattt atattctata tcactgacaa
    19921 tacctatcaa atcagactta ttagataaaa tatcctcata cttacctttt ctagttactt
    19981 ccaatctttt aaatctataa tttttatatc cttctatgat aatcaagtcc atatcttcat
    20041 ataattgaat cattttatat aatggattct tctcttttag ttcttcaata tatgctactc
    20101 gtttatctga tattatacag acttttctcg ccccagattt tctatgttta taagtatctt
    20161 ttccttcctc atccatatca aaatcatggc aggtatgttt aataactcca acacgatacc
    20221 cttttttatt taattctttt attatgcctt caatcaacgt agttttacct actcctgaat
    20281 atgagacaac tgacaatata ttatacataa aattgtgtcc tttcataaaa ctatctaata
    20341 acaatctcca ctaattgatt ttcttttatt gtctcattct ttttaatctt aatcatacaa
    20401 ttacttctta gagttgcaga taatctagct tttgcatctt tcttatcatt tagctctaca
    20461 tacaatttac cttcacttgt atatagtttt ccacttacaa atctatcttt atttgaaagt
    20521 ttattaaatt ctcctttaaa tatagctttt atatgatgta ttcccttctt atatgttaaa
    20581 tactcaataa caggaactat cacattatca aataccacta ttgctgcatg tggattacca
    20641 gaaagaccaa ataatagctt ttctcccaat atacctacat aacaagctcc accaggttta
    20701 atgtttatct tccaaaataa ttctgttgcc cctatttttt tgaatacatc tggaattaaa
    20761 tctttatctc caacagaaac accacctgtt gtaattaaaa aatctacact ctgtaacata
    20821 ttctttacct ttttttctaa ctccaatata tcatcagaac aattgcatat tgtatctgcc
    20881 tgtattccaa gttttaataa tcttgaatat aaggtatatc tattactatc gtatatttta
    20941 ccattctcta aagtctcatt tatatcttgt agttctgtac ctgtattcaa aattccaact
    21001 tttaaatcat cataaacagt tactttggat attccaagac ttgctaatac tccaatacca
    21061 tcatatccta tattctgatt tttattaata atcaattgcc ccttttttat atcctcaccc
    21121 ttaaatatgt aattatcgta ttcctttaat tttacattta aaattatcat atcacctata
    21181 accgttacat cttctttttt tattacacag tttgcaccct gtggtatctt tccaccagtc
    21241 attatcttca ctgcttcatt tttatttaat accttattaa atacttctcc tgcatacaaa
    21301 gtccctataa cctttaaatt tctattttca gaatttgcat tatatgcata accatcatag
    21361 ggtgacctat caaatggagg actatcaatt gttgaatata tatcttctgc aactacttta
    21421 tttactgcat ctataagatt tactatcttg accctgttta ttggtaaaac atttttttca
    21481 ataattttta tggcatcttc taattctatc attttaaata ctccccaata tattttttat
    21541 ttaagatatt tctatgtaat atattataga ttataaaagt tggaaatact tttatcttat
    21601 atttaattat aactaatagt tatctataag tgcagttcaa attttataaa tctaataaaa
    21661 aaactgttcc cagctagaaa tttccttcta tcttgaaaca gcatcatatg ctttagaata
    21721 ttttattcta ataaagttcc ttttattatt tttacaattt tatcactttc aatagttttt
    21781 atagatttta ttttgttatc cacaatactt attgtaagta cctctttttt taatattttg
    21841 ttatcttctt tcaatctata actcttaact actttactac cttcatgatt atatgctgtt
    21901 aaatcataat tcgcatctcc tacaatttca tttattctag actcttcaac accaacatac
    21961 tctcccaggt caatacgtct aaaattttct agtgatacag ccgatttttc atggtcactt
    22021 ttttcaatca caacactaga ttcagcatca atgactgata taccttgtga tgagaaagaa
    22081 ttggtttcaa cattgacaac tttattttcg ttaatatcaa catataaagc acttccatct
    22141 agttcatcat ttccagtata ttttggataa actaatgtca tataacttga tgtatttata
    22201 tcttgcattg tattcgattc ttttaaaact ttaggtttta tataataaaa tgtattataa
    22261 ggtataccca tattctttat aatgtactta taatctttat tcataatttc attaacatca
    22321 ttttgaactt ttgtcatagt tttttgctgt gttgctttac ttgctacttg atttttctct
    22381 ttagtatttt ctttatgaca tccaacaagt ataataccta aaatagttac acaaactaat
    22441 gaccttttta acttcataaa tcaatcctcc tttcttaaat tttatagtat ttatctatat
    22501 ctcaatttac agttatctct tttttcaata attatattta ttatattata aaataattat
    22561 ataatattta tttgaattta ataagattaa gaagctaatt gtaatttttc tgtaataaaa
    22621 aacactttaa agttgaattt tgaaaattca atttacgata tttttattgt aagtacctta
    22681 caatattata ccaaattatt cctaaacaat caaaaactcc atgaatattt aaaggttttc
    22741 tattttaaaa atcacctttg actattaatt tatcaaatat gttataatag ttttagataa
    22801 tttaaggagg attaaataat ggattttaaa caacttgaag tatttgttgc tgttgcaaaa
    22861 catcagagtt tttcaaaggc cgcaagagaa ctttttttaa ctcaacctac tgtaagtgca
    22921 cacatacaga atttagagag agagttggaa actgttctta taaatagaag caacaaagtt
    22981 attacactca caaaatctgg tgaaattctt tatgaacatg ctatatatat attgaataat
    23041 tgcaaacgtg caatttatga tataaaagaa tattcaggaa aaatagaagg tattatagat
    23101 atagcatgta gttccatacc tgaaacttat attttacctg attttatgaa gagtttttct
    23161 atgagttatc cagatgtaaa attttccata agccattatg attctcaata tgctatatca
    23221 gaaattttaa atgaacgaat aagctttgga ttagttggtt ctaaaatcaa taatcctcaa
    23281 atagagtacc tagacttatt agatgatgaa cttgttctta tcactccttc agattttaaa
    23341 attgataata aaaataattg tatcgatata ggagaattgg cttatctaaa ttttattatg
    23401 agaaaagaag ggtcaggtac aagaaactta atactaaaca cacttagtaa aaataacttt
    23461 ccagtaagta aattaaatgt aatagctcat gtagaatcaa atgaggctat taaggaaatg
    23521 gttagattag gtcttggagt ctcctttata tcgtacattt cagctattga ttatctcaat
    23581 gcaggtaaaa taaaatgtta taaaataaag ggtgttgatt ttactagaaa atttttcttt
    23641 atttactcta aaaagaaaac tttttcccca ttagaagata aatttctaaa cagattatgt
    23701 gagtatttcg aaattataat ataataactt taataaagta gtgcttaatt ttgggtttat
    23761 aactaattaa taagctaatt ataactatca cataaatgct tataaattat tatgaaccat
    23821 ctttcttttt tatttaattt agtcaaaaaa tccctcgttc aaatgaactt gggatttttt
    23881 tatttatact attccaatag cagctaatac tatacaaata atcataactg aaattaatat
    23941 cgtagttgtc tttacctttt ttcctaataa ccaatacata ataccgaata tcatagctgg
    24001 aagcatacat ggcattattt ggtctaagta agtttgaata ggctctgccc attctccact
    24061 acctacatta acactaagtt ttaacattac attagatgca gtcatacctc caattaccat
    24121 aagccctaac attgaagctg cttccataac ttttgaaact atacttgaac tactcacatc
    24181 tttaaagaat tgagttccat acttaaatcc tttatctaga catatatagc gtataataaa
    24241 atgaggaaca tttattatta aaaggaataa aatcggtccc attatgttac cctgagaagc
    24301 taaagctata ccaactccag ctgctataag ctttaatgtt ccccagaaaa atgaatctcc
    24361 tatcccagaa actggaccca ttaaacttga tttaacagca tttatactat tagcatcaaa
    24421 ttctttattc tttgcatttt cttcttccat agctccagat atacctacca aaagagtact
    24481 tatatgagga gtaactgaca taaattctaa atgtcttttt aaagccttag atttcttttc
    24541 cttatcatct ttatacaatc tacggattat tggtgccatc atgtatgcat atgctatatt
    24601 ttgcatacgt tcgtagttcc aagatgaatc taatgtcaat gaccttctaa agcatttcca
    24661 aaagtctttc ctcgttattt tactatcggg tgaaattgta tctaacttct tagaactcgt
    24721 tgtcatctac tattacctcc ttctctccta caaagttaac atatattaaa gctattgcta
    24781 atccaaacaa tgcaactcct gttactgtta tgtttaggta agcaaccaat ataaatccta
    24841 ataataaaaa tgctactgtt ttcttattaa gcatcatcct agctaacatg gcaaaaccta
    24901 ttgctggaat cacgcctgct gcaacatcca ttccatgagt tacatatgat ggtataaatg
    24961 aaagtatttt ttctattact ggaacaccta atgaaaatcc tatacctact attattgcta
    25021 atattaattt atttcctata ccaaataata attgcacacg ttctacgcct tcaatattcc
    25081 cctcttctgc ataacggtca gcaatatgag ctccccatgt aagtactact gtcattaaga
    25141 agttatctat aagcaatact agagttgcta taggaactgc aagtacaact gctgctgata
    25201 catcttgacc cgttaatatt acaaacgctg tggcaataat agaaccagac acaaaatcag
    25261 gaggattact tgccccaaca ggaaatgcac ccataaatac taattctaat gttgaaccta
    25321 ttactatacc tgtatgaaga ttacctagtg ctaaaccaac aagtggtgca acaactatag
    25381 gtctattatg cattgtagaa cctacaaaac tatgcatata tgcaaagaat gcaattagag
    25441 ttatcaaaat aacttgtgta aattccattt tcatccccct aaaattatat taatttcatt
    25501 acatttgtag catcatcatc aggaactaat tgtacaaata catttacgcc ttctgaatct
    25561 aactctttaa tcatctttat atcatctttt gatacatgca ctgctttaga tatattttca
    25621 cgattatcat ctgattttgt tccaccaagg tttatagatt taatagcttt tacctcttta
    25681 gcaagtctat aaacatcttc tacagattca caaagtatca ataagttata tttatcagta
    25741 acacctgagt taagtgcttt tatagaatct gctatgcttt tcattactaa cttaacatta
    25801 gatggtttag ccattttaag ccctgccatt cttaattcat cttttaataa ttcatcactt
    25861 gctatcaata tacagtctgt gcttaaaaac tttgtccatg taaatgctac ttgtccatgt
    25921 ataagtctgt ggtctactct tactaattta atcattataa ttcctcccta atttttttga
    25981 tttcatccat gaatgttttt acgtgttcta cactaacatt cccaaaatct ttgtaattat
    26041 ctttaaagta acttcctatt attgccatat ctcctaattc aagctgtttt tttgcatttt
    26101 ctaatgtaac tccagcagct ataaccaatg gaaagtctcc taaattttta cgaaacagtt
    26161 ctattttttc cattgatgtt tcttgacctg tagcattttc tgtaactgct atagcatcac
    26221 atcttgtcat tcctattttt aaatcttctt caacgtcatt ttctgataat actggctgat
    26281 atttaaaacg tacgcctcca attaaatacg ctgggcattt tgaacgttgt aatttaaaaa
    26341 attcttctaa agtagcttcg tctctaggtt taacatgacc tactacagaa tcaacctgta
    26401 tataactagc attatatttt gttgccagtt caaatcccat agtatcaaca tttaaacaat
    26461 ttactccata tggtattgac aaattagctt ttgatacata ttcaagtatt ctttctaaat
    26521 cataataatt accatagtaa ttttctaaca ttattccatc tacaccattt tcttcaaaga
    26581 ttgtaatctc ttttttagct ctttcaaaga tatcttctgg agtatctcct tttaagtgta
    26641 tcattgctat aattggtttt ttacttttaa atactgataa tattcccttt tttttcataa
    26701 actaaaatac ctcttcttct tctttaattt gtaatgtcac gctttgtatt cctcttctag
    26761 attcttccac taattgttct atatcttcaa ctgttaattc atcagaaaac cttgtaagaa
    26821 gttctaatac catattcaaa ttcattccag aaaataactt aacattatgt agattagtta
    26881 atcttaacat tgctgtacat acacttgctc catataagtc agataaaatt atatattcac
    26941 attctatatc ttctgatatt gttttttcta attctaaagc aaaatctgaa gcactttgtc
    27001 cagggtacaa accatacgaa ctaacacaat ctgctaaatc tcctactatc atttttactg
    27061 catttaaaag cccttttgaa aaatctccat gagatgctaa tattatcttt ttcatacttc
    27121 atcctcctac taaatataga ttatatttct gctgatactg catatttgta cttatcactt
    27181 cttataaatt gctcattgta atataagaca tcattatttt ctgtatacac cgattgtctt
    27241 actttcaata gtggcatatt acttgcacat ttaagatagt cagaatattc tttgtttgaa
    27301 tgttttactt caaatatatt ttctactcgt ttaggtaatg tgcttatatt attagatata
    27361 acctccatta aagatttatc ttctaattct tcttttaata aaaacatgta atctattcta
    27421 aaatagtcaa cttcaaaaat aacaggtact tcatctatta atctaagtct tttaatacat
    27481 attaccttct cttctagttc aatacttaaa gcttcagcta cttgcttatc tgcttttttt
    27541 attaaaacag agattatttt ggtacttggt tttgcattaa tacgatgaca agaattagta
    27601 aaactatttc ctgcacatgt tgcttctatt ctctctggta ttgttacata agtcccttta
    27661 ccacgttttt tacataatat atcttctttt acaagttcat taagtgcatt tctcacagtt
    27721 atacgactta tattaaattc tttacataag tctccttcag atggaagttt atctcctggt
    27781 ttatatatgc cagatgctat ttgttttttt atgttgtcat atagttgttg atataaagga
    27841 acaaaggaat ttacttctaa atccatttct tttttttgtc tcttttcatc cattttgctc
    27901 acctccctat gtaacatttt tataacatta tataacaagt tctttattac atattataac
    27961 aagatgaaat cgttgtcaat ttttttttaa ataattttta atttgacagt attttctttt
    28021 attttctcta gtgtgacaaa ttgctatttt tacataaaaa taagactgtt gtacaacaga
    28081 ttaaattgtt tatacaacag cctttattca cttattacat ttatattttt acttataaat
    28141 ttatattaaa aaatgcctta tatcccttat acatttcata tatgtctact ttagagacaa
    28201 tctcatgtgg tgcatgcata tttaaaactc caacaccaca gtctataacc tctgcacctt
    28261 gatttgccaa tatatgggct atagttccgc ctcctccttg gtctactttt ccaagttcag
    28321 cagtttgcca tactacattt cctttattaa aaattctctt tacttctgac ataaattcag
    28381 cattagcatc attacatcca ctctttcctc ttgaacctgt atacttagtt aaaactactc
    28441 catttcccat atatgctgaa tttctctttt catatgcttc tccaaaattt gggtcatatc
    28501 cagcagaaac atcagctgat aataccttac tatttgctaa agctcttctt actttaatat
    28561 cacaataatc tccttctaaa gcaatcagtt cagccacagt attttcaaaa aactttgagt
    28621 gcatacctgt attcccttta gaaccaattt cttctttatc tacacataat gcaactgaag
    28681 taaattctgg ttgttcagtt tctagtatag cttttacagc agcatatgaa cataccctat
    28741 catcatgccc atatcccaac accatagacc tatcaaaccc taaatctcta gccttaccag
    28801 ctggaactac ttcaatttca gcacttaata agtcttcttc aactatattg tatttctcat
    28861 ttaaaatctt taatatattt gctgttatag gttctttttc ttcatcttct aaaggaatat
    28921 tcccaattaa tatatttaaa gcttctccac taattccttc tgatagtttc ttttgcattt
    28981 ggtctccagc caaatgaatc aataaatcag ttacacaaaa tactgggtca ctatcttctt
    29041 ccccaataga tatgtccact tttgttccat catttaatat aactatacca tgtaaagcaa
    29101 gtggaagagc tgtccactgg tattttttta ttccaccata ataatgagtc ttaaaaaaac
    29161 ctagattact ctcttgatac agtggatttg gttttaaatc taatcttggt gaatctatat
    29221 ggcttcctat aatcttcata cctttttcta tataattttt acctattaca aaaagtgcta
    29281 ctgccttctc tttatttata acataaatct tatcaccaca acttatgctt cctttttcca
    29341 tagcttcatc tattgaaata tagttatttt ctttagccaa ttttataatt tcttttactg
    29401 aaagtctttc agtctttgac ttacttaaaa actccatata attgcgagaa tattgcataa
    29461 tttgttcaat agtattttct tttctttcaa aatcccaagc attcttaaat tcgtacttta
    29521 agttcatatt ttcctcctac taagttctaa tttttattgt ttttcatgta ttgctcatat
    29581 tcttctggtg aaactacttt gacactatct agtcttgatc taaagtgagc tctaaagttt
    29641 tctaaatatt ctttccttaa aatttctctt tctttgattt catcagcaga aaggattccc
    29701 tctttatttt tctttgctaa ttcattaatc ctatctaatt tcttcttgtc aaacattttt
    29761 tcctcctaaa aaacctctat ttatttaata aaataattta ttgcttttta tatctaactt
    29821 gtttttatat tcacaaaaaa actcatctat attatcactt attacagata ttcccttttc
    29881 tagttcttcc atgcttgggc gagctatatt tatcctaaag aatctatcat ccactagatt
    29941 gtcaaaaaaa taagttcctg gaagcattga cactcctttg tttaacataa aatttgtaaa
    30001 tgcttgagat gtatatcctc ttggtaattc taaaaaaaag tttattcctc cacaagattt
    30061 tctaactttt aatttaccac tcaatttgtc attaatcaag ttttttgaca atttatactt
    30121 attagtatat atcttctcta tatgactcaa ataattcttc caatcaaaat tattcatata
    30181 gtaatacatt gatttttgaa ttaaacctgg tgttgatata tctgatgaat atttagccca
    30241 taaaactttt tttaacaact catttggcat ttctacaatt cctatcctaa gacctggcat
    30301 aagtattttt gaaaagcttt ttatatatac tactctattt ttatcatcat aacttctaat
    30361 tgttctattg tcctttgatt caaaaacaaa atcacttata aaatcatctt ctattatata
    30421 aaaatcatgt tcttctgcca attctatcaa tttctttttt ttatatgttg agtaagatat
    30481 tccagttgga ttttgaaaat taggcataat gtatataagt cttggtttta ttttttccaa
    30541 ctttaatttt aaaataccta tatcaattcc atcatctaac ataggtatag atattatttt
    30601 tgcacctcta cttttaaaca cttcaattgc tccattgtaa gaaggttctt ccataaaaac
    30661 aacatctgaa taacttataa gtcctttaca aactatatct ataccttgtt gagcacctga
    30721 tattatttga atattttcct tagtagtttt tatatttcca tcacttagat actctaccat
    30781 tttttctctt aattcttcag agccaagacc ttcatcatat tcaaatattg aactaccatc
    30841 tttagataat gccatattta cagcattttt aaatgaatcg ataggaaaca tatcattaga
    30901 tggattccca ttgtcaaaat gaattaaatc ttctctttgc acaataatct tatttttcct
    30961 gttatctata ccgcttttat aagaatttga acttgataca aaagtaccac tccctataat
    31021 tttatataca tatccttcat tttctaaaag ctcgtatacc ttaactatag tagtgttatt
    31081 tacttgtaaa aaatttgata gttttcttat tggaggcaat ttttcatgtt ctactaactc
    31141 tttatttatt atcaattctt ttatatgatt aaatatctgt atatatttag ttgatttttt
    31201 ctcatttaaa tctattctgt atttttccaa atttatcacc gctcattgta tttatatttt
    31261 attgatgctt ttatatatat ttgatattat ttagtatgta tatataatac caaaattttt
    31321 ataaaaaggg gaaatattta tgttttacga ctatcacatg cactcaagtt tctctacaga
    31381 cggaaaatct acaatggaag aaatggtaaa aaaatctatt gaactcggtt tggaggaaat
    31441 ttgtttcaca gaccatgttg actatgatgt atatgctgat gattcttttt caattgtcta
    31501 cgaagattat tttaagagtt tagagactct tcaaagcaaa tacaaagata aaatatcaat
    31561 aaaaaaagga attgaatttg gagttcaaac tcaattaatg gatacataca aaaaggaagc
    31621 acatcaatat ccattggact ttataatatg ttctatccat gctatagata caatggactt
    31681 ataccttggt aattatttta aagataaaac tcaatatgaa gtttatgaaa attactatct
    31741 ttatttatat aatattgtta agaattataa agattactct gtcttaggtc atttagattt
    31801 gattaaaagg tatgcacctt atgacactat tttagatgat agactatttt ctgatataat
    31861 tgaagaaact cttaaacaag ctatttatga tggcaaaggt atcgagataa atacctcttg
    31921 ttatagatat aatcttccag acctaacccc atctaagtat atacttcaaa tgtacaaaga
    31981 cttgggaggg gaaatcataa ccacaggttc agattcacat catataagtc aagttgcatg
    32041 tgagtttgac tacatatatt cattactaaa aaatatggga tttaaatatg tatctaaatt
    32101 taataaattg aaaccagaat ttataaaatt ataaattttt acacctcctt gtgaatatat
    32161 ttaaaagata aggaggtgat ttttttgaaa gtaccttatt tagtactatc aacagttatt
    32221 ttatttatat ccaattttat tgtaagaata tttggttttt tatataaaat attcttatca
    32281 agagcactag gtgaaacagg tttaggtatc tatcatatga tttttaactt tttgatgatt
    32341 tgcttagctg ttacaacaac aggtatacct actgcactta gttgtctagt tgcaaagaga
    32401 aaagctttaa acgatagaca caatactaat gctctattta tatcaacttt atatatatca
    32461 tttttcgtag cactaattat atctatagtt gcatctttca atagttcttt tttatcactt
    32521 aaatttttaa aagatgctaa attaaatcta tttatactag ctgtttgtcc tgctatagtt
    32581 ataataactc tttcaaacgt actaagagga tattactatg gcataaagaa tgtaaaaatc
    32641 cctgctattg gacaaatcat tgaacaaatt ggtaaaatat tatttgtttt tttacttgtt
    32701 atgtacataa ataataaatc tatgaattgt tatatagctc tattaggtat atctattggt
    32761 gagttgagca atattatatt tatgcttatt tgcttatggc gagattcatc atttgacaat
    32821 aggtatatta taagcataaa agatttttat aattcttcta tggaaacatt aaaaatgtct
    32881 attcccataa cttgtaatag aatgtcaaac atacttttgc aatctataag ttctatgatg
    32941 ataccatcaa gattagcatt atcaggaatg acttatcaac aatctttaag tatgtatggt
    33001 attgtcagtg ggatggtaat gccctttata tttttacctt ttactgttgg ttcagcgctt
    33061 attgtaaatt taataccaac tatttcacag gaaatggctc taagaaagcg taagagtgta
    33121 attaaaaaaa tcaaatactc catacttctt actttatttg taggcatact atcatcaata
    33181 tttttttatt tctttggaaa agatttatgt atattagtat ttaaaaatac acttgcagga
    33241 gaatatctaa aagctatgtt tttagttcca ctatttatgt ccctaaatca aactctatct
    33301 ggcattttac attcaataag aaaagaatta gcttcaagta taaatactat tactggcatg
    33361 ttaattcaac taatagcttt atatgtattt cttccaattc caggacttaa tatttatgca
    33421 tacatataca caatgacgat agtatcaatc tttacttgtc tattacatac tatagtgctt
    33481 tttaaatcac taaaatctat acgctagtta taaaaacgtg aaggctacca atgtaaatta
    33541 tacactttgg tagccttcct tagatgattt ttatttataa tttaaactgt ctatatatct
    33601 tacctatcta tctgtggcaa cttggctttc cacttccatg attaggtcca cattgcgaaa
    33661 aatcacatac tttagagaaa gtatcaacaa gtcttggttg gattggattt ggtgatgcta
    33721 aaactactat ttgttcactt attaatgtgc taactgtttc ttgtaagcaa agtactaaat
    33781 ctatatcatt tggtataatt aattcataga aaggttcaca acattcgttg cattctaatt
    33841 ttaatataga ttttcctata caatctacag ttaagttagt ttgatattct tgtcttaaag
    33901 taacagctct tccgtcagct ggcaagcata ttggtgctga aagtgtgtta aaagtaaatt
    33961 ctacataatc aactcttctc ttacatccac ctcctgctct aactgctggg aaagctaatg
    34021 caacgaactc tgtacatcca catctacctc ttagctctag tactaaatta cgaactgcta
    34081 cagttaatcc tctttgttta taagctactg atttgccttt tccttgtcta cagcactcag
    34141 cgtttctttc tccacaaact gcaaattcaa aagttgtttc acagtttctt cctactatat
    34201 ctcctaatgg gtctaaatcg aaatcttcta aagttgtcat tcctgtgtct ataactattc
    34261 catcattact taagcatatt ttttctatag ttacacttgc ttgacctgca cttggaattg
    34321 aaccaaatac ttctactact tctgtttcaa aagttaatgg ttctccattt ggacctgttg
    34381 catctgtaaa tgtttggaat tgcatagtat caaatattct attagcctct attgcaaatg
    34441 gcactgcatt tgatacagag aagtttcttg gagatatcgg attacaacat tctggtccac
    34501 atttgttttc aaaacattca tctgaatcca tttcacatgg ttcacaatca catttacact
    34561 tgtcatggca ttcacatttg tcatcacatg gattaggttt gcatggattg catgggttag
    34621 gtttacatgg attacatggg ttacatggat tacactcatc atggcactca cacttattat
    34681 cagtattaca tccattatga tggtgtgatt ttttaaaccc tctcatgtct tctgaattta
    34741 tttcatctgt atacacttct tcttcattca ttgtagacat tggctgattc atcattcttc
    34801 ttttattttt tttataatct tgcatttttc attgccctcc ctgtaagcga ttcttattaa
    34861 gtctttggct ttttgaagcc taattaatac tatgctttta taatcttaat tgttacttgc
    34921 tttttgaatt tatcaataat taggcgtatt tagtagaaaa atgcatatta ataaaaaaag
    34981 tactactatt tgaaatagta gcactttttt tgtcccgaaa caccggtggc taagtaaatt
    35041 cacaccctag gcactcccag gtgggtgact tgccagtaac ctttaacgtc caaactaact
    35101 aggcatgtta taatttacca gacacggtct cccgtatttc atttgtaggt tgaatttaaa
    35161 aaagccttat cgtatgtttc aggatttcat attattatta tataataaat tttgaatttt
    35221 ttaaagtggt tttatatagt aattgagata atcttattct atcattactt tttcttcctt
    35281 ttttctttat gtatttagtt aattatcgtt ttttcttagc tctagtttta gtattttttt
    35341 cattataatt gtattcggat tcttgctcat taatgttgta tagttcctca tcgtatacta
    35401 tatcttcatc attttctata ttttcatagc ctgtgttctt atcttctact aattcatctt
    35461 cattatcctc catttcacct tcatctgtta actcatcatc atccaattct ttgtcttcac
    35521 aatctaattc ttcgtcttca taatttaact catcattatt gtcttcatca tcattattac
    35581 tatcatcacc tcttaaaaga cttcctaaca atttgagatt attcatacta ccaagattgt
    35641 ttatatttgc caaagagctc aaactaaatc caccttcacc aaagtcatct ggtaaaaata
    35701 attctgcaaa taaatctatc ttctttttca ttcctatagc tttttcaact gaattttttc
    35761 ttttttctgg gaatacatct ataatttcct ttatcatcat attcttttta tcatcactat
    35821 ccatttttct gaaaaaatcc gtttcatctt ctgtatctac catatctata ttatttaatt
    35881 tttttattcc tctaactaaa tctaaaacac tttctatttt tattagtatt tttctttcat
    35941 ctcttgacat gtatttttta gttcttgtta ttatttccat tcccatttct aaatcttctt
    36001 cacttaaatc catgagcctt aaacctcttt ttatatcatt tgcatcaaac cttaaattgc
    36061 catgtgtaga ctgtgaaagt ttatcatttg catttttttt gttttttcta actctattat
    36121 ttccttttga tttattttta tcatcaaata tagagatatt accattactc aatgcaatca
    36181 ctccaatcaa aaatagtaag ttattcaaga caattccccc ttatattata taattgccct
    36241 atattaaagt atgtttttca tattttaatg ttccattttt aaagctcagt gcatatatat
    36301 tatctataag aatttttatt tatattatat atcactcaca attcaccact tcaatattat
    36361 ttctatatat aaatagtatg aatataattc aatatatatt tatagaaagg ggttttttta
    36421 tgaaaaaatt agatacagag tcattagaaa aaatggctaa acaaaaaaat attgacaagg
    36481 ataaaataga aaagatggct gatagttaca aaggaaaatc agaaaatgaa cttatggagg
    36541 aacttataaa aataggtaag aacttagatg gaagagatga agtagtatca aaattcaaag
    36601 catttttaga tgaaaatcaa cgcaaaaaac tagataatat aatggaaaaa atctcagatg
    36661 cagaaaatca aagagatact aaaccagcta aaactaagaa ggctaaacct actaaaggta
    36721 aatcaaattc acctgcacca aaaaatacac caggtggtca acaaaaaaaa tctaaaggtt
    36781 tatttaagaa aactaaaaag tctaaccctc atgagtagat aaaaataaac tatttaagta
    36841 attagataat tatttttagt taatctatta ttaaatttga tattattgac ataaaaaatc
    36901 aggtagtgcc ttaggcacta cctgattgat tttaatagtt ttattttttt ctttctgtaa
    36961 cactttctct atcaacaatt ctataaggta attctatttt cttattttca attaattcct
    37021 tatttattaa ttttataacc attcttattg ctactgctcc catatcgtat agaggttgat
    37081 atactgtagt aagtttaggt ctatacattc tagctatctt aacatcatta aatcctgcaa
    37141 cagatatgtc ttctggaacc ttatatccag catcacatat agcatttata gcacctatgg
    37201 cagcctcatc acctgttaca aaagccgcat gaggtattat tccatcatct aatagttctt
    37261 tcatactatt gtatccactc tcataatcag ttccaccata cttaatcaaa ctcttgtcta
    37321 attctatatt gttatttgaa agtgctttct cataaccagc aagtctttcc atttctaaaa
    37381 cagtatcatc tttactcgtc attataaaag ctatcttttc atgacctttc tttataagat
    37441 gctctgtcat atcaaaagta gcttcttcgt tgctagtact tactgtatat atatcataat
    37501 ttctagcagt tttacttata tatgtcgctg gtattccaca attttgtata tagttgatat
    37561 gttcttgttc aactatccat gaaatcataa ctataccttc cacttgtttt gctctcaata
    37621 gatttatact cttaagttct tgttccttat cagagtatgt attcgctaaa agaatatcat
    37681 agtcatacat tttagcaact tcttctatcc catttaacac ctcattaaca aaagaatctg
    37741 aaacttctgg aactattacc cctattaatt gactcttctt tgttactaag cttctagcaa
    37801 gtggatttgg tatatatcca gtctctttta taacctctaa aactttttgt ttgacttcat
    37861 cagttacagg ttttgaatca tttataactc tagatacagt agatattgac actcctgctt
    37921 gtttagcaac atcttttatc gttatattgc ctttcatctt catcctcctt attttactaa
    37981 atttatctaa aactgaacca aatttttgaa ggttcctatt ttaactacat ttatataagt
    38041 ttttatttta ccataaaagc aagtacattt aaatacatta tattttatat tataccctat
    38101 attcaacaaa tttaataata ttcattctta atttaaatca tattaaaaaa taaaataaaa
    38161 aaatactggt ataaaatacc agcatttttt tattctaatg atttaagtat tagcagccgc
    38221 aacctacttc accatcaaag aatccaccac atgaacaagt tattagcaat aatattaaga
    38281 aaggtatcca tgacattatg tcaatgtctc tccagcaatc ttcaaaagct aagaatagga
    38341 agaatagtac tattatccac catcctcctc caccaaagca tccttcttct ccaaaaaatc
    38401 tatctaacat aacaaagccc tccttttttt aataactgtg ttcttattct aagcatccac
    38461 cacagcagca aagtattaat aaaactatta ggaatggtat ccatgccatt atgtcaaatt
    38521 ctgcccagct atctccaaaa gctaagaata ggaagaatag tactattatc caccatcctc
    38581 ctccaccaaa acatccttct tctccaaaga atctatctaa cattgtacgt tacctcctgt
    38641 tgatattttg ttgagctttt cgctcctaac atatactatg catttggttt ccattttgct
    38701 aatgtatttt tactattttt ttaaattttt taatttgaac taaaaaaggt aaaaccataa
    38761 cttgtataag ttactggttt tacctattta ataatcaata ttttttagca acaacaacca
    38821 tcatcgaagt taaataataa caatactatt aatataaccc atatccatat attgtcatcg
    38881 cataataagt cttctaaaat gtctgtgcat aatagtaaga atactataac tattattatc
    38941 aacattttat taccaaaaaa tccttcgcat cctccaaaga aacgttccat attgtcttct
    39001 aattttgtca taactaatcc tccttgaatc attaagagac taagttttgt ctctttaatt
    39061 aaatatatgt agtaatagac agataagtta cttctaaaaa gtttttattg attagtttat
    39121 ttatttcttt ttcaccaagt ttattgtatc tatcaacttc atccagataa tcttttttct
    39181 cctctgatat agtgtagatt aaactttcta ttgattttat tttgtactcc ttatatcttt
    39241 ctatcaagaa ggatgttttt gaattttcta ttcctttctt tacatgcatt aaccttgata
    39301 tgtagtcttc tttttcatta gatacataac tctccttttc agctacatct tcaaggatta
    39361 aattggtctc cattacataa tcctctatac gttgcatatc taaagttatt gaattataat
    39421 aaaaatttac tgctataagt aaaaacattc ctactgaagt tagtaatagt cctacatatt
    39481 tcatagcatt tcctcctaag ttatatttgt tatcaataaa gtttattcat caaataatac
    39541 tttattacta catttataaa attttattat tttttataga ttccatattg aaaaattctt
    39601 gatattatat taaactaaca ttaaaattaa ttaaaactgc tttaggaggc ttaaaatgtt
    39661 tgagaaaata aaagaaataa tagcagaaca attaggggta gacaatttag atgagataac
    39721 tatggaagca tctttaatgg acgacttaga agctgattca ttagatgctg ttgaaattat
    39781 aatggccctt gaagatgaat ttggaataga aataccagac gaggaagctg agaactttaa
    39841 atgtattggt gatatatgta aatatatcga agaaaacaaa tagtatcgtt ttgtctacaa
    39901 atataaatag tctgtgtaaa cttctacata ataaattata ttagagttcg cacagactag
    39961 attacattta tttacaatat ataaaataca cgctcttata tttaatttat atactaagta
    40021 tataaattac ttttcttcat aaaatgtaac attctttatt attatatcta tagttccatc
    40081 ttgattttgc tttacagtat acttcattgg gtcttcaaaa tcagttagat tcccttttat
    40141 gtcaaaacca ttatccgttt ttatacttct ttttttaagc tttttctcaa cccatttttt
    40201 atctatacta aaactttcat caagaccttt ttcttccata tgctctttaa agctatcctt
    40261 taactcatca tctttaattg aattatcaac aaagtcattt atatcaactt catgtttttc
    40321 cttcagtgta taatttaata tacttcttac atcttcagct tgctttatat cattactaag
    40381 agcattagtt atccaatttt cagctgtatt tttaaatacc ttggtcttgt acttatcatc
    40441 atctattttt ttagcattta aaaattctgt tacaaactta gattctgacc cttctttttc
    40501 agcatcctta tctaaaagcc ttagatgaaa ctcatcattt ataccactta aactaatcaa
    40561 agctccttgc ttttgtctta aagtctctgg gataccaatt tcatttgaaa ccatttgaat
    40621 attaaattta tcatccacaa attcaattga atgagtgtac aactttttat aatctaattt
    40681 cagtattgct acactctttt catctttaat agtgtataag caaattgcca aatcacaaga
    40741 ttctagtgca gcattaattt tcataacgtc aaacaagtaa gatgcaattt ctttagaatt
    40801 tttcaaaaaa gtactttcat catatattat ttgttcacaa cagtttttaa ttaaattgtc
    40861 attataatct ttaaaaacac cttttcttaa atcctcatct tttgcaattc tttttatagc
    40921 tttctggaaa aaaccatcta cttcttgatt aactttgcct tcaaagtcat ttaatattgg
    40981 aacatcacta tttttgtcca aaacatgtat tataaattta tgtattatca tatatatcac
    41041 cccattatct taatttcgat attaactctt tcatatcctc tggtatatct gctttaaatt
    41101 tcaatttttc ttttgttctt ggttgttcaa actctagctt gtatgcatga agtgcttgcc
    41161 tatttattag ctcttcatct acataaccat acaactcatc acctattatt ccatgaccta
    41221 tatgagccat atgtactctt atttgatgtg ttctaccagt ttctaagctt acttctaata
    41281 cagttgcatt ttctagtctt tctattactt tatagtgagt aacagatgac tgtcctcttt
    41341 catctattat cctctttatt gaatcttctg taggtctata aattggctca tctatagttc
    41401 cctcattttc ttttataatt ccatcaacta ctgttatata ctttttttca actttatttt
    41461 cactcattgc tgtagataaa gtatgatgtg cataagcatt ttttgctact ataactaacc
    41521 ctgaagtatt catatctaac ctatttacaa atcttatttt tacgttttct ttttgattat
    41581 ctatatagta actaatacca tttgctattg ttttatcata gtggcttttt gttgggtgaa
    41641 ctaccataaa tggaggttta ttcaccataa ttatatcaaa atcatcataa attatctgta
    41701 aatttaaatc ttgaggttca aaatttgctt tttcctcgtc tatttttact tctattaaat
    41761 caccactata cacctttaaa cttggttttt tatatactcc atttactaaa acactctttt
    41821 ccttcttcat ttttgataat gacctaactg agaaatttag cttgtccaat aaaacttctt
    41881 ttaaagtcat ttcttcttca tttgtatacg atataagatt atatctttga ttctcttttt
    41941 taaacaaact tttacctact ttcttttata tcttcctgct ttttatatct tcaaaatcat
    42001 gatattatat attttacact atttttgttt aatagataat aattattttt aactataaaa
    42061 acctgtaaga ataacaaata gttattcata caggttaaat tcataattaa atatttaatt
    42121 tgtaaatatt ataatctaaa actatctctt aactattaaa gtagttccca ttccaccacc
    42181 tatacaaagt gtagcaagac cagttttagc atctcttctc ttcatttcat ataaaagtgt
    42241 agtaagtatt cttgctcctg agcatcctat tggatgtcct atagctattg ctccaccatt
    42301 aacattaact ttattcatat ctatatttaa gtctcttatt acagctacag attgggcagc
    42361 aaatgcctca ttagcttcaa ctaaatctat atcttcaata gtcatattag cagcttctaa
    42421 agctttttta gttgctggaa ctggtccata tcccattatt ttagggtcaa caccagctgt
    42481 tccataagaa actatagttg caagaggctc tattcctagt tcttcagctt tttctttagc
    42541 cattactact agcatagcag caccatcatt tattcctgat gcattaccag cagtaactgt
    42601 tccatctttt ttaaatgcag gtcttaactt agcaagtttt tccattgtag tgccaggctt
    42661 aatatattca tctttatcta ctacagtgtc accttttctt ccttttataa caacaggaac
    42721 tatttcttca tcaaattttc cttcagcttg agctttttca gctttatttt gacttgcaag
    42781 agctaattca tcttgttctt ctctagttat attccattgc tctgctatgt tttcagcagt
    42841 aatacccatg tgatagttat taaatatgtc tgataatcca tcttttatca ttgaatcaac
    42901 aaaagcagca tcacccattc ttgcaccata tctcgcactt ggtactaaat aaggagacat
    42961 actcatattt tcagctccac caactaacat tatatcagca tcacctaatg ctataagttg
    43021 agatgccatt gaaacagatc ttaatccaga accacaaact atatttatag tcatagctgg
    43081 tttttctact ggtattcctg ctcctaatgc tatttgtctt gctatatttt gtccaagacc
    43141 tgctgtaagt actcccccta aaagagattc atctatcata tctggagtta tgttagctct
    43201 ttttatagct tctttagctg ctgttacccc taactctacc gctgaaactg atttaaatgc
    43261 tcctccaaaa cttcctactg ctgttctagc tgcactggca attactactt ctctcatatt
    43321 cattaccccc attaaattag atttttcata tatccgaaat tgttttttaa acaattttat
    43381 ttaaactttt aattcccaaa ttcttattta ttataatcat agaatcctat cttagttttt
    43441 cttcctaatt gattagctct aaccatttta gctaaaagtg gatgaggtct atatttagta
    43501 tctccaaatt cagtatataa aacgttcatt atagctaaaa caacatctaa tccgattaaa
    43561 tcacctaatg ctagtggtcc cattggatgg tttgctccta atttcatagc ttcatctatt
    43621 tcttctttac ttgcaacacc atctgcatat ataccaacag cttcatttat cataggtata
    43681 agtattctat ttactacaaa tccaggagat tcagatacat ctactggtac tttattgata
    43741 ctcttagata attcaaatac tgtatcaaaa gtaacttttg atgttaactg accacttata
    43801 acttcaacta atttcatcat aggaactgga ttaaagaaat gcattcctat aactttatct
    43861 ggtctcttag tagaagaagc tatttctgtt atagataatg atgaagtatt tgttgccaag
    43921 atagtatctt ctttacataa ttcatctagt aacttgaaaa catctttctt tatattcatg
    43981 tcttctacag atgcttctat tattaaatcc atatctttta aatcttcata attagtagtt
    44041 gaactaacat gacttaatat ttctgctttt gtagcttcat ccatttttcc cttagtaact
    44101 aacttagtta aatttttatc taataaagct aaacatttat ctatagcacc ttgagttcta
    44161 ctctttaaac atacatcatg tccacaactt gcaaaagttt gtacaatacc acttcccata
    44221 gttccactac ctattacagc taatttcata gttataacct cctgttattt tagtatttat
    44281 attctgttaa ctagattaaa atactattta atctagttaa cagcaaatat atttttaatt
    44341 agatttttac ccttttataa agttagcttc tctcttttca acgaaagctg acattccttc
    44401 tttttggtct ttagttgaaa aacaaagacc aaataaatta gattctatat ctattccagt
    44461 atttatatca gtttgagcac caagttgtat tgcttcttta gagtatctaa ctgcaagctg
    44521 agcattttta gctattatct tagctaattt ctcaacttct tctattaaaa tgtctggctc
    44581 aacgactcta tttactagcc ctattttttc agcttcatca gcttttataa cttgacctgt
    44641 aaagattaat tcttttgctt ttgccattcc aaccaatctt gtaagtcttt gagttcctcc
    44701 atatcctgga gttattccaa gagttacttc tggctgacca aatttagctt tagcagatgc
    44761 aattcttata tcacatgcca ttgcaagttc acatcctcca cctaaagcaa atccgtttac
    44821 agcagctatc actacttttt tactattttc tatttctcca aaagcttttg ctcctaagat
    44881 actaaaatct ttagcagcta cagcatctaa atctttcatg tatgcaatat ctgctccagc
    44941 tacaaatgcc tttccttccc ctgtcaatat tacaacatca atagtttcat cattattaat
    45001 atctacaaat acttcataaa gttcttctaa agtctttgaa tttattgcat taagggcttt
    45061 aggtctattc attttcactg tacatatatt tccatctact tcaacagcta cattctcata
    45121 aactttaaca tcacttgtac tcataatacc ctccccaaga aattagttag ctaaaacttc
    45181 acctttttct tttgcaacac ttaactgact gataagttct ggaagcactt tatgaacatc
    45241 tccaactata ccaacatcag catatttaaa tattggagct tctggatttt tatttatagc
    45301 aactataaac tcagcatctt ccataccagc tatatgttgt attgctccag atataccaca
    45361 tgctatataa aggtctggtc ttacagtttt accagtttga ccaacttgtc ttgctttatc
    45421 taaccaacct gcatctatag tggcacgaga accagaaact tctccaccta taatttcagc
    45481 taattcataa agtatgtcta agttttcttt tccacccatt ccacgtccag cagaaactaa
    45541 tatcttagca tcttctattt taacttgttt tttagcttct tttattactt gtacaacttg
    45601 aactaattta tcagcatcat taaattctac cttgaaacgg ttaattacag cttctttagt
    45661 ttcatcaggt tcatttttct tcataacccc tggtctaact gtagacattt gaggtctgaa
    45721 atctttacaa actattgttg ccattatatt tccaccaaag gcaggtcttg tcattaataa
    45781 taattttgta tcttcagcta ctgcaagacc tgtacagtca gcagtaagac ctgtatgtat
    45841 tctagcagaa actctaggcg ctaaatctct acctattgaa gttgcaccaa ataatacaac
    45901 tatagggtca gctgctttta ttgcttcata agctgctttt gtatatggtt cagttgtata
    45961 cactgctaaa gcttcatcat ctactactat tacctcatct gcaccatagt gtgctaatgt
    46021 atctattaaa ccttctacct tactacctaa aagtaatgca gaaacttttg tatcataatc
    46081 ttttgctatt tctgtagcct ttcctagtaa ttctaaagaa acagtttgaa ttacattttc
    46141 tctttgttct attactacta aaacgttacc cattctttat ccccccttaa attatatgat
    46201 atacttctct tttaatttat ctatgataat tccagctgat gttttcgcat cttcattgta
    46261 tattgtacca gctggtttaa ctgattttgt aaatgattta aatacactag ttggagaacc
    46321 tttaagacct aaattagaag ggtcaacttc tatatctttt acagtccatg tttctactac
    46381 atcattttcg aaagcatcat atattcttcc aactttcatg tatcttggtg tgttcatatc
    46441 tttaagagtt gttataaggc atggcatttt aacttttaag tcatggcaac aatcttcaaa
    46501 ttgtcttttt actaatacat attcaccttc agtttttatt tcttcagcat atgttattga
    46561 tggaagattt aaatgttcag ctatttgagg tccaacttgt gcagtatctc catctatcgc
    46621 ctgtcttcca gctattataa tatcaaaatc tatatttttt aatgctcctg ctaatgctga
    46681 tgaagttgcc caagtatcag cacctgcaaa tgctctatct gttaataata tacctctatc
    46741 tgcacccatt gctaaagctt cttttaaagc catatctgct tgaggaggtc ccattgttat
    46801 aacagttaca tgagcaccca tttcttcttt taattttata gcttcttcta aacctgcttt
    46861 atcatcaggg tttattatac ttggtactcc atctctaatt aaagtacctg tattaggatc
    46921 tagtttaact tctgttgtat ctggaacttg ttttatacaa acgactatat tcataaatcc
    46981 ttcctccata tctattttaa tatcgaccta ttgtgtatat tttaatattt atctatttta
    47041 ataattttcc tgaaataacc attctttgaa cttcactagt tccttcatat atttcagtta
    47101 tcttagcatc tctcatcatt ctttctactg gatagtcacg agtgtatcca tatcctccat
    47161 gaagttgtac agctttcgta gtaacttcca tagctgtttc agctgcaaat aattttgcca
    47221 ttgctgcttc tactccataa ggttttccta agtctttatt tatagctgct tgatatacaa
    47281 ggtgtctagc cgcttgtact ttaacttcca tatcagctaa ttggaattgg gtattttgga
    47341 attttgataa tggtctacca aattgtactc tttcttttac atatttaaca gtttcatcaa
    47401 gagcaccttg tgctaaacct aaagcttgtg ctgctatacc aattctacca ccatcaagag
    47461 tagacattgc tatcttaaat ccttgacctt cttttccaag taaattttct ttaggtattc
    47521 tgcaatcctc aaatattaat tcactagtag ctgaacctct tatacccatt ttcttttctt
    47581 taactccaaa gctaaaccca ggagttcctt tttcaactat aaatgctgat attcctttgt
    47641 tccccttaga tttatcagtc attgccatta ctacatatat gtcaccagct attgcatttg
    47701 ttataaatat ttttgagcca ttaagtatgt attcatcccc gtctaaaaca gcagttgttt
    47761 gttggccaga cgcatctgta ccagcattag gctcagtaag accaaatgct cctaatttat
    47821 ctccacttgc tagtggtttt aagaattttt gtttttgttc ttcattacca tattgatata
    47881 taggccatga gccaagagat gtatgagctg ataatataac tcctgtagta ccacaaactc
    47941 tagacaattc ttcaactgcc attatatatc ctacagtgtc tccaccttct ccaccatatt
    48001 cttttggata tggtataccc atcattcctg cttttgccat tttttccact gtttcataag
    48061 gaaatctttc ttcttcatca agttctgttg ctaaaggttt aacttcattt tcagcgaagc
    48121 ttacatatag ctctttaagc atctgatatt ttttagaatt taaatccata atagcctcct
    48181 cagtatttta taaatatttt attttcattt attaattaaa atctcggcaa catctataat
    48241 aaggtatttg aatatacgtc gagaaattta taaccttaat caaactacgc tctatattta
    48301 tatgtgatta tactaaccaa ttatgacatt aatttaatca taaattgtta atttaaaatc
    48361 aactatactt aaaaaaaatc tcgctttttg gaattttgtg aaatttcaag ttagaataag
    48421 atttctttca cactggtcac agataaaata atttgtttac gatatttata ttagggtata
    48481 ttaaacatta aatattgtct gtacatctgt tttttagcca tgtacagaag atttttatcg
    48541 tataaaaatt attttaatag agctaaataa tcgtattttt atctgactat tttttatttt
    48601 taaatatctt acatctataa tagtaacact caaaggataa tttttcaata atttctaatt
    48661 atttttttaa caatatttat tacatttttt ccactttttt gtcatttttt tattgtttcg
    48721 aaaaaaaatc agaatttttt aactttattt tggattatta gtttaaatta gattttcctc
    48781 ttagatttat aaatatttac acaaaaaact acctctgtat agattgtata cagaggtagt
    48841 tttttactaa ttcctactat agtttactat atttttttac caattcttac aaacatctac
    48901 ccatttttca ctcttagaaa acttctccat ttcttcacat gtaagttcta ttgcagagtt
    48961 actactgcca catgcaggaa atactgtatc aaatctcttc attgaatcat ctaaatagac
    49021 ttttatagaa ttttttaaac caaatggaca gactccacca atagcatgtc cagtaaactc
    49081 caagacttct tctggtgtca acattttagc cttacaatta aattcagcct tatacttctt
    49141 attatcaatc ttagcatcac cagctgtcac aattaaaatt gcatcatctc ctattttaaa
    49201 tgagagtgtc ttagctattc ttgctggaat aaccccagct gcttcagctg caagttccac
    49261 agtagcacta gattgttcaa attctaatat actgtcttcc ttgccaaatt gtttaaaata
    49321 ctctcttaca ttacttattg acattaaata cccctcctag tctgaatttt tataaatttc
    49381 atattattct taattatatc tataattgat ttatttttca aattattcca taatattagc
    49441 attccatgta tcattatttt ttccaactac tagataaagt ccttttgcca ttggaatatt
    49501 gacaatatat tctcctttat attctacact cataccagat tcattaaagt acctataatc
    49561 aaaatttagt ccttttggaa ttacaaaatc aacataacct tgattatttg gttttattcc
    49621 atatttcaga gtactttcag ttatagaatt tttttcatta aataaatcta catttacata
    49681 tgcagaacac ttattcattc cctttttatt ttccacacaa ttttcaaact tcattttagc
    49741 actgtttaat ttataactat atttactatt attgcttatt ttaaatctta caatagtacc
    49801 gatatctcta cttctcctgc tatcaaaatc aaaaacaatt tcctctaaat gatttatttc
    49861 ataatctttg acacttacca tatctctata tactaattta tttatagcta tgaatagtgt
    49921 aaaaatcccc aaaataaaaa atgaaacttt tataaacttc ttcattttta gtctccttat
    49981 attttgtgct attgtgctat aatattaatt aaaattttaa taattaaact tattcttttt
    50041 tgaaatctta atagaaaaat acattgatat tataaaaatt attattgtta aaaatgtcat
    50101 actatataaa tttatatact tagtattagc tatatcagtt acataatttg aaagatatac
    50161 tcctccaact ttactataat taaaatgctt tacttgatat acaatcatac taatcatctt
    50221 caaaagactt ccatatacaa agtaaattaa aatacttact ataaaaccac aaactttcat
    50281 ttttccatat ccaaacttaa aaattaaagg cagtaaaatc gtcaaaattg ctaaaaatat
    50341 atttacagaa aaaaatacat catttaaaac catatttcta aagaacacta gtgatgtcaa
    50401 tttacttagt aaggacacaa ttattgttac agaaattatt agtcctacac ctaataaata
    50461 ttttgagtaa actatatctt ctatactaac tggcatactc cttataaaaa tccttgaatc
    50521 attttcataa tcacactcaa atgtatttat aaatatcaaa taactaacaa caatacttac
    50581 tgtataatat gaaattgaat taaggaaaaa ataaaacaca aaaaatagca atatgtactt
    50641 taaattacgg ataccatctg aactaattcc tattattaaa tcttttctta ttaaattgaa
    50701 catcctctca cctcatttac ataataatac attagttctt ctatagtagg atttttgacc
    50761 ttatgcttat caatttctat caataggctt tttactttca agctatctcc aactttaaca
    50821 agtgcctcat tataatattt atactcttta acaccaacta tactttcttt aattgcttct
    50881 aactctgctt tatttgccct aattatctta tattcttgtt ctattaattc tttcttaaca
    50941 gtaaaaatct gatttcctct atttataaaa acaagataat cagcaatttt aattaaatta
    51001 tcagtattat gagtagaaat tattacacta ctacttccat ttttcacaaa atcttgtaag
    51061 tactgcatta tttcagttct tacaatcggg tctataccag cagttggttc atccaaaatc
    51121 aataacttag cattatgact aagtgcgctt gataacataa gcttctcaga ttgaccttta
    51181 gataaatttt caatatgcat attttcttct atgtcaaact tattaaggta ttcatcaaat
    51241 ttttctctat caaaattctt ataaaataaa gaaactattt ttctaaattc cttaaccttt
    51301 aaatgtggat aaaattgtaa agaatcatat acaaaaccaa tattgttttt aaagcttatt
    51361 ggagaatttt caatagtttc attacaaagt tcaatttcac cttcatctgc atcaataatc
    51421 cccattataa tttttattaa agtcgttttt cccgaaccat ttggtcctat aatcccaaca
    51481 atatcccctt cctttaactc taagtttata ttatttaact tgaattttcc taattttttt
    51541 gtgatattcc ttatgctaaa cacatcttca cctcttatgc atttttttat acccacctat
    51601 acatatttta acacattcac tacaaaggtc atttataaat ttataaatta agaattataa
    51661 aactatgtta taatacaaag tatgaagagg tgaatatatg aaaagaatta taactataaa
    51721 tacaaaccaa ttaaataagt cccttgagac taaagaactc ttaactagaa aacttatcaa
    51781 tgctggcttt gaagtgtatt cagatattta tccagacaca gagcttatta tatcaattgg
    51841 tggtgatggc tcttttttaa gaacagttag agatttcgat tttcctgaga ttcccataat
    51901 gggaataaat acaggtcatc tggggttttt tcctgatatt ttaccagata agattgatag
    51961 ctttattgaa gcttatacaa aaaaagatta tattattcaa gaaatgtcac ttcttaatgc
    52021 ggaagtatat acaactacta gtggttctaa tatgcttgct gtaaatgagg ttgttataag
    52081 aggagacaag tctaggacta tacacctaaa tttaagcctt gataataaac atatacaaaa
    52141 ttttagtgga gatggtatga ttatttctac ttccacaggt tcaacagcct ataactattc
    52201 tgctggaggt agtattgttg atataaatct tgaacttatg cagattacac ctttacatcc
    52261 gataaatacc aatgcatata ggtgctttac atcaagtata atatgttcaa atgaatctgt
    52321 tataaagatt gcaccagaat atagatttga agattctgta ttgattgtcg ttgatggagt
    52381 tgagcacaga tttagacaaa tcgaaaatat aaaagttagt atatctgatg caaaaataaa
    52441 attacttaga atgtcaaact atgagttttg gcatagagta tctgaaaaat ttttatagac
    52501 tgtacttagg aggattttta atatgaaaat aggaataatg agtgatactc atggtagctt
    52561 actttacttt gaaaaagcgt taaatgtatt atctgattgt gatgttttat tacatggtgg
    52621 agatgtctta tatcatggac ctagaaatga tattccagaa ggatataatc ctaaaaaatt
    52681 tattgagaca ttaaataaat tagaaaacat tgtgattgta aaagggaact gtgatgcaga
    52741 tgttgaccag atggttatag aacatcctat tcagagtcct tatgtcatga gccaatttgg
    52801 tgaaattaga attatattga atcatggtta tatagaatca gaagaagaaa ttattgacaa
    52861 agcaaagaaa atgggtggtg acatattagt tttaggacat actcatgtaa aaaaactata
    52921 catggatgat aatttaatag taataaatcc aggaagtact tctatcccaa aagatggaag
    52981 ccattctgtc gcaattatag atatcataaa aactgatgat gaggatgagc ttgaacttga
    53041 tataaactta attgacatca atactggaaa tataataaat atcaatgatt agtaaatttt
    53101 taataaaaat aaaataagct ttaatttatt aaactcataa taaaaacaag taaaccattt
    53161 tatttctatc tcaattagaa gtttaagtac aataccttaa acttctaatt aaatagaatc
    53221 tggtttactt gttttattat atgctatatt gaaatataac ttagtttact tgtttctatt
    53281 atatattata ttggagtat
//
LOCUS       DAMJWO010000016        51764 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.017, whole genome shotgun sequence.
ACCESSION   DAMJWO010000016 DAMJWO010000000
VERSION     DAMJWO010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51764
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.017"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            143..493
                     /locus_tag="PC366_001027"
     CDS             143..493
                     /locus_tag="PC366_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDF2576565.1"
                     /translation="MSAKVTNQYGNIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            512..2155
                     /locus_tag="PC366_001028"
     CDS             512..2155
                     /locus_tag="PC366_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HDF2576566.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKELVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVENDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGEFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGDNIEIKNVDLDTNI
                     STSMDFAKSTTSTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKHINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALNSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            2236..4293
                     /gene="recG"
                     /locus_tag="PC366_001029"
     CDS             2236..4293
                     /gene="recG"
                     /locus_tag="PC366_001029"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HDF2576567.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDGEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKELIIQEYMPQRIIEKYRLCSIDFAVRNIHSPSSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIISALPFKLTKAQNRALDEIIQDMNLEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQIRNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGANPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETIAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMERFKNKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            4352..4906
                     /gene="rsmD"
                     /locus_tag="PC366_001030"
     CDS             4352..4906
                     /gene="rsmD"
                     /locus_tag="PC366_001030"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HDF2576568.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKSCTFVDISKESIDIVKSNVKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            4908..5405
                     /gene="coaD"
                     /locus_tag="PC366_001031"
     CDS             4908..5405
                     /gene="coaD"
                     /locus_tag="PC366_001031"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HDF2576569.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            5409..5933
                     /locus_tag="PC366_001032"
     CDS             5409..5933
                     /locus_tag="PC366_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576570.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLREIL
                     EEVKRDKAELRPKK"
     gene            6277..8196
                     /locus_tag="PC366_001033"
     CDS             6277..8196
                     /locus_tag="PC366_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2576571.1"
                     /translation="MKERAKKILDFIIKNNNVTSQELQERFNVSKRTIYYDILAINEQ
                     LGKSGNIKNVKHKFIFEGNLCDARKIISTEEDKFLDSDYRKTFILNKILLGEKISIEK
                     LTNEMLLSKNTVVQTITDVKKYLQTMGLRLEYKGKYKIIGDEYVIRELFLIIVQENVL
                     EINSISKEVSSFDTKGHIKLTDYSLLNLTKFVEFLNKRIRDGKTLYSYKYLNEAKKIS
                     YFSNCKELLCEEANENEQAYICTYISSLPSLNSEVKEDVVEEYVDKLIDKFEVNTAIK
                     LESKHEFKKNILRHLHSSYNRIRFKFPIRNPMLDETKYKHESLYKIIKSIIENEEEFP
                     VFEGIREEEIGFIAAYFGGYLRGSRDNGLRRNKVLLVCPNGLMVSKSLEIQLYKYIPT
                     IEIVGIVSIKQLKEVNVYYDYIITTIDIQNVNNVIVVNPLLTSSDVQLLMNKLISVKE
                     NEKYFNLELIIQAIRKNGVINNEEALKADLLNIIHKIDEGEMYQPMLKELINAERVNI
                     IKSVRDWKEAIKIASKPLLEDNSIEELYIENMIKSVEKYGPYIVLADRFALPHASSKE
                     GVNKLAMSLLIVEDEVDLLGKPVNIFMVLAAVDNTTHIRALASLSEMMYEEENVKLII
                     NGDKSSILELINKQN"
     gene            8209..8496
                     /locus_tag="PC366_001034"
     CDS             8209..8496
                     /locus_tag="PC366_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2576572.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIQKALKQLGIECEVENTDINSARG
                     ADCDCIFTSQELLNELKGTCNVDVYPVKKYMDLAEVTEVVQTFLSDKNDKK"
     gene            8629..9888
                     /locus_tag="PC366_001035"
     CDS             8629..9888
                     /locus_tag="PC366_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDF2576573.1"
                     /translation="MLDFISNNILRNPSMLIGLIAAFGLVLQKKKASDVIKGSLLAAF
                     GIIIMETGTGMLVSSIAPINGAFQSISGGAVTKGLSDVTFTASYGGIIGLAMFAGLAI
                     HLMIARFTPIKTIFLTGHMLYWFPFIFVASGVEAGLNGGVLIAFAAVLSALYWSIMPW
                     LLRKYVFDVIGDDSFTLGHPSGCLALISGFVAKLVGNKEKSTEDINIPQSLSFFREIS
                     ISGGMAVFLMFIVVGIVIPGAFKDSNEFIGTYAIKQGLSFGAGLIIMLHGVRMLINQI
                     MPAFQGISEKVVPNALPAFDCPILFNYKPNAVLIGFLVAMLTSTAMILICNYFNVFNL
                     LLIPLVITSFFECGAAAVIGESQGGIRGAIIGTAIAAIFMVVLVGISAVIYSGTIQNW
                     ILIFGGNDLSLFGIISKFIGSLFGGIL"
     gene            9891..10631
                     /locus_tag="PC366_001036"
     CDS             9891..10631
                     /locus_tag="PC366_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2576574.1"
                     /translation="MKFKYIDEIRRLIDIIENEEKVNMEKAVQILVEAIESKNAIFSF
                     GASHAGILTEELFYRAGGCVLINPVFAKSLMLDTAPITHTSKMERLEGYGTALADKTP
                     IKKGDVVIVHSVSGRNPVSIEFAMKAKENKAIVICITNLSYSKSVSSRHSSGKKLYEV
                     CDLVIDNHGQKGDACVEIDGLNQKVSPTSTVIATTVMNSIIAQATQELVNKGLKNPPI
                     FYSANIDGGDELNKKIFDEYKSVIHYEY"
     gene            10954..12264
                     /locus_tag="PC366_001037"
     CDS             10954..12264
                     /locus_tag="PC366_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDF2576575.1"
                     /translation="MKKENKMEGIKVGMLKKLCSLAMVAIMTTTLITGCSSGNGKDSK
                     KDGEKEKLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISA
                     GEGPDVGYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAA
                     NPGVLYYNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFG
                     NLNWNWYPYLWQAGGDIFNDDLKSVKFNDKSGLEAANFLKELQAYVPEDSLSKDSNEM
                     IESVFGPGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLMSS
                     AKNKELAYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKNVYRPL
                     VVGPHGVEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            12362..13279
                     /locus_tag="PC366_001038"
     CDS             12362..13279
                     /locus_tag="PC366_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDF2576576.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVAFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTVVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGSIWSLQVFDLIYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVKRDNSDF"
     gene            13295..14104
                     /locus_tag="PC366_001039"
     CDS             13295..14104
                     /locus_tag="PC366_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDF2576577.1"
                     /translation="MKTARRLLSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFFNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDAMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            14161..15909
                     /locus_tag="PC366_001040"
     CDS             14161..15909
                     /locus_tag="PC366_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HDF2576578.1"
                     /translation="MEISYVLKDCTFKHNKYSVIEAETWKEKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTIDKSSTISWKGLENRVRLALNVPNSLENNFSINILGYVQDDTKAFVN
                     DAILRDKDVLVEQYLPQTFWIEGQVPEDFEENNLNIGIDIFKSFGYEDEEKVCTIDVP
                     VKVRNVVLKPLDKSKFFLDLWQHPSCLARMYKVELWSDIHFEIVDNYLKELASLGEKV
                     ATVIVSDYPWAGQSCYKVYKNPSNLYEYNMVSVSKGLDGKIKCNFESMDRYISIADKY
                     KMSKEIDLFGLLGNWCAGEFGNPVEGYKDPIRVRYFDENDKVFKFINNTNDLKEYIGL
                     VLNHLIECGLWDRVRIIADEPNNPEVVKECIEFINSTVGTHQVKYKSATHDQNFLDRA
                     KDEIDDMSINLKLTIQNYKDIENLKKKINDKGGILTWFVCCFPEKPNSFLSSPFVENR
                     IIGWYTYYFGLDGFLRWDYNLWTEDPWKDSSYKFPIWKAGDMFFVYPGKDLKPVRSVR
                     MENLRFGIQDFELFTMLEKEKGREYIEVELMQELLNKKENAEIKGFGDIELGYSLDNW
                     GYDKVKKYVLELLDRV"
     gene            16172..17194
                     /locus_tag="PC366_001041"
     CDS             16172..17194
                     /locus_tag="PC366_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HDF2576579.1"
                     /translation="MFGGINIKRIGIIIMFFLSIAFIGFYLAIRGNSDTVKMQRGINI
                     GNALESPKDFPWDVKMSNKFFDDIKDAGFDTVRIPVRFSDYTSDSDNFKIDEEFFKKI
                     DKYVDYALDKDLIVVLDLHHFEEIMKEPRVHKEEFLKIWQQIANRYQKYDKKLVFELL
                     NEPKENLSSQLLNEYIEEAIKIIRKTNPKRTIIVGPYNFYQIDYLNELNVPKDSNIVV
                     SFHYYEPNDFAFQGNIYHNGFEHLSNITWEGTNEQMDYLKKRFDIVENWANKNKVKIF
                     LGEFGVTKEAPEASRRAWIKAVREEAEKRNFSWAYWELASGFGIYNQIEGTWDRDILS
                     ALIEKR"
     gene            17199..19505
                     /locus_tag="PC366_001042"
     CDS             17199..19505
                     /locus_tag="PC366_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2576580.1"
                     /translation="MKKNSKKILITLTIITNIVYILWRIFYTVPKEEGMFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPVISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDKKKVHIYICDDGNREEMRILAEKMGVNYITRTEREGAKAGNLNNAMQHTNS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSEGRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPEVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLVFWLPMYILS
                     SLSLKIFSQNIRNTRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKNKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSMTYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYIAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEVEFRE
                     KSGNEMYIANMKAKIVNVVEVNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKIRTLSRRSPRINMNFQMDIKNTGKLRIVNFNYQYVLLNF
                     ENKNIYPKEIALEINENIVLECDLCEGKIDERGLLYKVNNIDSIMQNFFLRDEMMDWI
                     LQNKTIPVSNPSEKKEKSIDEFEPMEYI"
     gene            19477..20592
                     /locus_tag="PC366_001043"
     CDS             19477..20592
                     /locus_tag="PC366_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576581.1"
                     /translation="MSLNPWNIFRRDEMKTLKVFFCSAKYLILVFIFFINTTFISSAT
                     SDKILDLSFKKIETDLSSRITYEDTGVKIETDSSKSDKERYLYIYQNIKENWSMYNNF
                     YIEIQNKNKSSQKINLSIQSKNMLEFRLKEGSEIFLEDKNIIYSDKIKEGCIEVPGEF
                     EGKIYVNFNSLINEKSNVVLDSSMLSNIVSWGITFIPSDEEHNIVIIKKISLLSEEKL
                     SFLHNIKITGNEEVQIPVLGQSISQYEVLGLKRDSKIKYSLMGKQDNVSISQNGKLTL
                     SNKAEPGQIILQVNVDDKFKIGRKIALTESWSINKKDKDGVPYTLVSPEQSPTVQYMK
                     KINFMNNIITFVRILFVSLVIICFGIYLYWKKCSKTK"
     gene            20610..22028
                     /locus_tag="PC366_001044"
     CDS             20610..22028
                     /locus_tag="PC366_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HDF2576582.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYVFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMIVSIIMNYIFGLLVDRYRESKIKVKVFLVLMCVYNIGVLFIFKYLAFAL
                     RNISELINTELTIPSIVLPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTMQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRSPNLKEAYNYFKAMLGG
                     NGVIWSDYTYMFLKEYWVFFIFAFIFSVPIAKKINKFVVEQAKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            22043..23251
                     /locus_tag="PC366_001045"
     CDS             22043..23251
                     /locus_tag="PC366_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576583.1"
                     /translation="MNRFFKVRLITAIMFLIILFAFSIFNICYSGKDMIQEIKNSVAE
                     KSSLKDTISSIDNTVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSVVKDTSGKMHYTY
                     FAKAPNPVGVIADRVRKFSEEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNETA
                     DNFLNQLKKYNVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELVEQLNKK
                     YNMNLDENHYYRDKENYNSIVYPKSFLGSMGRKTGILYGGIDDFTLIYPKFKTNYTYY
                     TDSKSQKFELKGRFEESLILSYPFNADLDLMDGQSDKYFTYLLGNRPLVKIKNIENPD
                     GLKVLFVKDSLIVPTAAFFSSVCSSIDMIDPRYYDGDILEYAKSHDYDFVFISVYPQN
                     LTKEFFPFCK"
     gene            complement(23332..24720)
                     /locus_tag="PC366_001046"
     CDS             complement(23332..24720)
                     /locus_tag="PC366_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HDF2576584.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVTWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKDNNLGTLTFKSLGMLLATTAIAAIVGIIVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IDFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFTIHLIFITLNGLNPITYIRNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSLYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     IDKEVFGKKNIS"
     gene            25062..26396
                     /locus_tag="PC366_001047"
     CDS             25062..26396
                     /locus_tag="PC366_001047"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HDF2576585.1"
                     /translation="MRVVIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFDDADELLARTPEKLREAGIDLNIFREVVEVDSESKKIKVKNIKTDEIYED
                     YYDKLMIATGARSIMPPIKNIKLKNVSTLKSLYDGEYLKKLLSNEDNKRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEMTDVLEEEINRHNVNLHLDEMVVELC
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSNTNIKMLKNGAIVVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREVSYQGSLSSSCIKIMD
                     MEAASTGITEKQAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVILGGQV
                     AGFKDAVQRANVLAAAIFGKMTTSQLGMLDLCYAPPFARTWDVLNVAGNVSK"
     gene            complement(26525..27442)
                     /locus_tag="PC366_001048"
     CDS             complement(26525..27442)
                     /locus_tag="PC366_001048"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011969064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HDF2576586.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMR
                     NLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLNSKQYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIP
                     SMYLENATNVFENTILGEDRLSLRLNFDE"
     gene            27650..28534
                     /locus_tag="PC366_001049"
     CDS             27650..28534
                     /locus_tag="PC366_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HDF2576587.1"
                     /translation="MKVLKKITILSLITLTLVGCSNGEDKKVVEGSKKIQNSKKDEQP
                     IIVHKDANILKDRYEPPKGFKRVDVEKGSFESFLRNTKLKNYGEKVKYYDGRIKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWAQGY
                     RISVKDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGKKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
     gene            28747..30588
                     /locus_tag="PC366_001050"
     CDS             28747..30588
                     /locus_tag="PC366_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HDF2576588.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLERFEEITIFHTNDIHGRY
                     AEGDDHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMDRGKSAIELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGKKVFDSNDIKEIDGIKIGFF
                     GLSTQETKNKTGFKNVEGLEFKNPIESATEQVNELKGKGANVIVAICHIGTNSLSKPN
                     SIDIANEVQGIDLIIDGHSHTKFENGKQVGDTLIVSAGQYLENIGEIKLTLDTNDVEN
                     IKIENKSVRLIGKEEALKYKLDYVVSKKVDEIKEQQEKILDKVIGATTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITRRDIVDVFPFSNTIVTK
                     ELTGAQIKDVLEHGVKLYPEKSSAFLQVGGISYYFNPKQKEGERITSIQKEGKPLDLN
                     KKYVVATNDYIASGGDEFPCFSKEPILKEFGNLESAVIEYIEYKKEISKNVDGRIGIK
                     SKDELISKNHESDLILSENEKNINDNEENLSNNIKSSDSDKNKSLDKTSARESSNQGI
                     SKREAKEKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKDKKSK"
     gene            30892..31599
                     /locus_tag="PC366_001051"
     CDS             30892..31599
                     /locus_tag="PC366_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2576589.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFGIEEAKNIFAKE
                     EICLIISDIGLPDGSGFDFCEEIRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIIRTDDKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSEPKYIK
                     TVRGVGYMWGERSIKKC"
     gene            31593..32903
                     /locus_tag="PC366_001052"
     CDS             31593..32903
                     /locus_tag="PC366_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2576590.1"
                     /translation="MLKNMNLKDGLSVKDDYIMRRVIVYSVLSVLIVTLVFILFEYSR
                     LHKLYEHQIKNTQNIAGILIEKYPNDEIDIVNSIYNSDYSKVSTGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIRYINKRLSKIYFIVDKMAQE
                     NYLKDTTESEETGYLVEYNEYFKEGTFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEKLEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILNAVKSVTPKAKSKSITLNLNEFNSRIIPHDKKWTEESI
                     FNVLDNAVKYTQVNGEINISVEETANFFKIIIEDNGIGIEKNEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            33020..33703
                     /locus_tag="PC366_001053"
     CDS             33020..33703
                     /locus_tag="PC366_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2576591.1"
                     /translation="MKILYTENLSKHYGKGENLVRALDNVNLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDESFIKELLKSLGLENKHDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGR
                     VSKVGDKND"
     gene            33696..36083
                     /locus_tag="PC366_001054"
     CDS             33696..36083
                     /locus_tag="PC366_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2576592.1"
                     /translation="MINTTKIAKSNLKQNKSKSILIIITIILSTLMLSSIGIYIVDAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGEMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFELIKGKLPTKENEIVLDSGALKALGYKNKDLGEKIKISYNDYKNDK
                     KIEKEFVISGILKTSEISEAGKYYYAIISELYMRNTRDMSQEDFNIYVKFNDKSNLSI
                     EQAKEKLDKIANDIGLDTINTAVNENYINALKPDMETIMGGGFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQIKNIVFKEGFILAGIAIPIGIILGYVLANIIIK
                     SFMDIDVKSSRLPVILSVVVISFISVVLSLLKPMKVASKVSIVDAVRYTGNKISNKSK
                     RKGYKNINLKRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKNNLNILQMDNPLSKDFFNQIKNMEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLNKNLIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTEEG
                     KYQEIKDSIKKIAKNNGFLETDFIDSRIESNKAVISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAMYYTSGMMIGSILFGGILGYIAV
                     IFLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            36362..37504
                     /locus_tag="PC366_001055"
     CDS             36362..37504
                     /locus_tag="PC366_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HDF2576593.1"
                     /translation="MNKKINYAPGPTETRENVRLARAEKTTNPDIDIDFVEFYKKTCE
                     KFGNIVGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDEDSNFKYATVVHCDTPTGVLNDVSKICPLLKEYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEGYYEKKYFPYTMPISDIMGLDKALDNILEEGIENVLDRHEKIAYSV
                     RKSIEEYGLELFLEEGYSNTVTAIKIPESIGALKLTDYMLKNYNTLVATSLNQYMDTI
                     LRIGHMGENANLNKIEHVLNVLDKSLSALGFKGNENLLNLFNKYYF"
     gene            37523..38047
                     /locus_tag="PC366_001056"
     CDS             37523..38047
                     /locus_tag="PC366_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2576594.1"
                     /translation="MEVTAKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIVFGSKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIA
                     WANGNNGNNFLINVIGICVSSIWMLFGYYITEVILYGNFIVPLTSIPGNLMQVLIGLI
                     IALPISKVLKKCIK"
     gene            38147..38965
                     /locus_tag="PC366_001057"
     CDS             38147..38965
                     /locus_tag="PC366_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2576595.1"
                     /translation="MLSVTRYSIKNVRLKPWVKFIWYFETKSNILLNNKLLPTDSIDI
                     ILNLSDVMEYKIENQDYTASNMHFNGIRDKHGFIIQHGNIRVIGISFYPFGLYPFLKI
                     PISEFNRQIVDLEAVSELFAKKLEESLNPTQSVEKIVLYLEEMLLSILEEDLISNKSV
                     KLLNSFIYDNRYSNIKAFCDNTNINIKTLERICLKYTGYTPKILKRIYRFKMASSQLI
                     YNYKDNELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFIGENKTIKENIKYNYL"
     gene            39043..39354
                     /locus_tag="PC366_001058"
     CDS             39043..39354
                     /locus_tag="PC366_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDF2576596.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSASSKMFKDSSTEKFRKALKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(39657..41660)
                     /locus_tag="PC366_001059"
     CDS             complement(39657..41660)
                     /locus_tag="PC366_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase C-terminal domain-containing
                     protein"
                     /protein_id="HDF2576597.1"
                     /translation="MKSQKRFKILDIDVYLQPFESDIKKRMKHYEDMKSKTLKNYKDF
                     SSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDN
                     NFDLKNITSPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELIKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAISLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLNFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDM
                     VEFGGNTKKENLRDYDVYFSSTPPSSKMPIASRTAIVLLDNGI"
     gene            complement(41813..42451)
                     /gene="recX"
                     /locus_tag="PC366_001060"
     CDS             complement(41813..42451)
                     /gene="recX"
                     /locus_tag="PC366_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HDF2576598.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKS
                     YNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTINEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            42727..43416
                     /locus_tag="PC366_001061"
     CDS             42727..43416
                     /locus_tag="PC366_001061"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HDF2576599.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            43417..43989
                     /gene="yqeK"
                     /locus_tag="PC366_001062"
     CDS             43417..43989
                     /gene="yqeK"
                     /locus_tag="PC366_001062"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HDF2576600.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSRNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            44106..44456
                     /gene="rsfS"
                     /locus_tag="PC366_001063"
     CDS             44106..44456
                     /gene="rsfS"
                     /locus_tag="PC366_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HDF2576601.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            44810..47230
                     /locus_tag="PC366_001064"
     CDS             44810..47230
                     /locus_tag="PC366_001064"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HDF2576602.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     gene            47657..47969
                     /locus_tag="PC366_001065"
                     /pseudo
     CDS             47657..47969
                     /locus_tag="PC366_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431045.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            48068..48736
                     /locus_tag="PC366_001066"
     CDS             48068..48736
                     /locus_tag="PC366_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF2576603.1"
                     /translation="METVSNNQSSVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVV
                     IFKKNSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFSEYIRLSQLGETFFNPNINLI
                     PFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHR
                     ATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALIL
                     GFFS"
     gene            complement(48894..49889)
                     /locus_tag="PC366_001067"
     CDS             complement(48894..49889)
                     /locus_tag="PC366_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HDF2576604.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGIGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC"
     gene            complement(50010..51638)
                     /gene="aspD"
                     /locus_tag="PC366_001068"
     CDS             complement(50010..51638)
                     /gene="aspD"
                     /locus_tag="PC366_001068"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HDF2576605.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDEI
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEDLFKFISKTASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
BASE COUNT        20068 a         5779 c         8912 g        17005 t
ORIGIN      
        1 tttatccaaa aacttttcta ggtttaaatt ataccatatt tatagtatga tatgattata
       61 attttatata ataaataagt aaaaatagta aaaaataaat taagaaatgt ttttaataaa
      121 aataagctta agggggtcaa ccatgagtgc aaaggtaacg aatcaatatg gaaatataga
      181 aatagataat caagtaatag ctcaagtcgt atatagagct gcaatggaaa gttatggctt
      241 agtaggttta gcatataagt ctaaaggaat agtagagcta ttaaaaggcg agaacgcaac
      301 taaaggtgta agagttgagg aagtagaaga agatgccata gcaatcgaac tttatgttat
      361 aatacaatat ggtacaaata tatctactgt tgccaataat ataatagata gagtaaagta
      421 tgtagttgaa aaaatgactg gcgtaagagt tactagaatt gatattaatg tacaaggaat
      481 aagagttaag taatttcata ggaggaaaca aatgattcaa tatatagatg gtaaaaggtt
      541 aagggagatg tttatttcag gtgcaaacaa tctccaaaac aataaagagt tagttgacaa
      601 gttaaatgta ttccctgtac cagatggaga tacaggaact aatatgtcat taacaatatc
      661 ttatgcctta aaagaattag caaaagttga aaatgataat atatcagata tcggaaaagc
      721 attatctaaa ggttctttaa tgggagctag aggaaactca ggagttatac tttcacaaat
      781 aatcagaggt atagctaaat ctatagaagg aaaaagtaaa ttatcaacag aagatttagc
      841 aaaagctttt aaaaatggtt cagacacagc atataaagct gtaataaaac caattgaagg
      901 aactatactt actgtagtta gagaaagtgg agagtttgca ataaaaactg cgaaaaaaga
      961 gaaagatgta gtaaagtttt taagtatgct tgtgaaggaa tcaaattctt cattagaaag
     1021 aactccagac cttctaaaga atctaaaaga agctggtgta gttgactctg gtggaaaggg
     1081 tcttgtactt atatatgaag gaatgttagc ttctataaaa ggcgataaca tagaaataaa
     1141 aaatgttgac ctagatacta atatttcaac aagtatggat tttgcaaaga gtactactag
     1201 cacagatgat ataaaatatt gctattgtac agaatttatt ttagaaagtt ctaaggtaga
     1261 agatactaaa ataagagaca taatgatggc ttatggtgat agtctagcag tagttggaga
     1321 tgatggagtc ataaaggtac atgtacacac taatgaccca ggaaatgtac ttcaagaagc
     1381 tctaaagtac ggtcaattat taactataaa aatagaaaat atgaagttac aacatgaaaa
     1441 tacattactg gatgtagaag aaaagaaaga aaatgatagt gaacctttag aagaagagaa
     1501 agagtttggg tttatagcta cttctatggg tgaaggtttg gcaaatatat ttaaagattt
     1561 cggagttgac catataatag aaggtggtca aactatgaat ccaagtactg aagattttat
     1621 gaatgctata aagcatataa atgctaaaaa tatatttatt ttcccaaata acagcaatat
     1681 aataatggct gctaatcagg caaaagaatt gagtgataaa aatataatag ttatacctac
     1741 aaaaaatacg cctcaaggat ttgctgcatt agtaactttt aatggagaat taagcgaaga
     1801 tgaaaataaa gaagctatga tgaatgcttt aaactcagtt aaatcaggtc aagtaacttt
     1861 tgctgttagg gatacagtga tgaatgaaat tgatgttaaa gaaggtaata taattggaat
     1921 tgcagaagga aatttattat cagcaggaga ttatgtggat gaagtaacat caaaccttat
     1981 tgaaaagttg gttgatgaag atactgctat aataacatta ttctttggtg aagatgttac
     2041 agaatctcaa gcaaatgaac tacgtacttc tttagaagaa aagtttgaag atgtagatgt
     2101 agagttatat tatggaggac aacctcttta ttattactta atttcagttg aataatgatt
     2161 ataagaacct gtatgaccaa gtagctttta taaaattggt tgtacaggat ttttgtgtag
     2221 taggtgatat atttgttgga tttatataaa gatgttcaat atgttaaggg aataggacct
     2281 aaaaaagcag ataaattaaa taaactgggt atatttacac taaaagacct attgtattat
     2341 tttccaagac aatttgaaga tagaaataat ctaaagaaaa tagcacaatt agaagatggt
     2401 gagaaagtta cgataaaagc agtaatatca agtataaata catttagccc aaaagaaggt
     2461 atgactttaa caaagattga tgtaaaagat gagacaggct cggctaaatt agtgtttttt
     2521 aataaaagtt atataaaaaa tacttttcgt ccaggagatt caatattagt ttttgggaag
     2581 gttaagaaaa aatttaataa cttagaactt acatcatgtg aattagaata tcttactaat
     2641 tcacctaaga atacatgtag atttatgcct gtgtaccagc ttacatacgg tgttacaaat
     2701 aaagaaatta tgagtataat tagaacagta cttgaagata aagaattaat tatacaagaa
     2761 tatatgccac aaagaattat agaaaaatat aggctatgta gtatagattt tgcagttaga
     2821 aacatacatt caccaagtag taaggaatca ttaaaaatag ctttatatag aattgtattt
     2881 gaagaattac ttatactaca actagggttg tttgtattta aaagtggcag aaataaagaa
     2941 gatggaataa agtttgaaac aagtaaagac ttaaaaaaaa taataagtgc tttaccattt
     3001 aaactgacta aagctcaaaa cagggcatta gatgaaatta tacaagatat gaatttagag
     3061 aaaataatga atagattggt acaaggtgat gtagggagtg gtaaaacagt agtagctctc
     3121 ttagcacttg caaattgtgt tttaaatggt tatcagggcg ctttgatggc acctacagag
     3181 atattagcag ggcaacatta catttcactt actgagtctc taaaagattt tggaataaat
     3241 gtaggtctat taataggtag tcttacaaaa aaacaaaagg atacagtatt ggaacaaata
     3301 aggaataatg agattgatat attaataggt acacatgcac taattgaaga taaggttgaa
     3361 tttaataata ttggtttagt tataacagat gaacagcata gatttggtgt tatgcaaagg
     3421 agcaaacttt cattgaaagg agcaaatcct gatatattag taatgacagc aacaccaata
     3481 ccaagaactt tagcacttat actctatgga gatttagata tttctattat agatgaactt
     3541 cctccaggaa gacagccaat agaaacaatt gctattgaaa aaagtaagcg agatagagca
     3601 tataataacc ttgtaagaag agaggttgaa tcaggaagac aagtgtacat tgtatgtcct
     3661 ttggtagaag aaagtgaagc tatagaagct aaatcagcag ttgaacttgt agaggaatta
     3721 agagctgaat atttccacga tttaaggctt ggattgcttc atggtaaaat gaaatcgagt
     3781 gaaaaagacg aagtaatgga acgttttaaa aataaagaaa tagatatttt agtttcaaca
     3841 acagttatag aagttggtgt caatgtccca aatgcaacat taatgataat agaaaatgca
     3901 gaaagatttg gacttgcaca attacatcag cttagagggc gagttggaag aggtagtcat
     3961 aaatcgtatt gtgtactaat ttatgattct aaaacagatg tatgtagaca aagaatggct
     4021 ataatggaag agaccaatga tggttttaag atttcagaga aggatttaga aataagagga
     4081 cctggagaat tttttgggac aaggcaacat ggtcttccag aacttaaagt agcaaactta
     4141 tttaaacata taaaaatatt gaagttagca caacaagaag ctcgatatat attgggtgaa
     4201 gataataatc tacaattgaa agaaaacatg gcactcaaaa aagaaattat agataaattt
     4261 aaagatacat tgaaagaaat ttcattaaat taattttaaa ttatgttaaa atattactaa
     4321 tgtaataatg tgctgaaggg agattgtcat attgagagta atttcaggaa aagcgagagg
     4381 attaaaacta aatactccaa aaaatgaaga tgtaaggcca actacagata gagtaaaaga
     4441 gtctctattt aatatgataa attcatatat aatggaaagt gaagttctgg atttatttgc
     4501 tgggactggt tctttaggaa tagagtgctt atctaggggt gccaagtcat gtacttttgt
     4561 agatatcagt aaggaaagca tagatattgt taagtccaat gtaaaaaagg caagagttga
     4621 aagtgaaagt attattttaa accttgattt taagactgca atagataaac ttaaattaca
     4681 aaatagtaaa tttgacataa tttttatgga ccctccgtat tataaaaata tgtttataga
     4741 agctattgaa aaaattgata attctaatct attgaacgaa gatggaataa tagttgtaga
     4801 acatgatacg aatgatttat ttccagataa gatatgtaaa ttggagaaaa ctagagataa
     4861 gaaatatgga aatactacat taacttttta taagatggag gcataatatg gaaaataaac
     4921 ctagaaaagc tatatttgca ggaagttttg acccaattac taatggacat ttagatatta
     4981 tttgcagggc ttcgaagtta tttgacgaat tacaaatagg agtattaaat aatcctaata
     5041 aaaagggtct atttagcttt gatgaaagag taaaacttat agaaaaaagt acaagccatt
     5101 taaataatat aaaagttgtg acttttgatg gtttattaat aaattactgt caggaaaatg
     5161 ggattggagc attagttaga ggtgtgagaa gtggtgctga tgttgattat gaacttcaga
     5221 tggcacatat gaatagagag cttaatccag atatagagac tataatttta ccaagttgta
     5281 caaaatattc atttataagt tcatctttaa taaaagaggt tttgctcttt gatgctgata
     5341 taaaaaattt ggttccaaag attgttttgg aagaattaaa gaaaaaaact agtgggggta
     5401 attgatatat gaagatagat ttagaaatga ttgaactatt tgagcagtta gaggagatat
     5461 ttagaagtgc ttctacaatc cctttctcac ataaatgcac agtggataaa gatgaggttt
     5521 tagcaataat taatgatata agaactttaa taccagaaga agtaacacag gcagtatgga
     5581 ttaataaaga aagaaataaa ataataagtc aagctaagca agatgctaca aatatagttg
     5641 aacaagcgaa aaaagaagct gagagaatac aacaagaata tcaagataat atagaggaat
     5701 taaagaaaaa ttctgaagat gtagtaaagg catatgtaga atccagcgaa cctgttgttc
     5761 aagcagacca aagagcaaaa gatatagttg atagagctga gagaatagcc aatgagataa
     5821 gaattgggtc aattgaatat gcagaggatg tgctttctag tgttgagtat aatttaagag
     5881 aaatattaga agaagtaaaa agagataaag ctgaacttag acctaaaaaa taaattttaa
     5941 ataaataaaa atggagctat cacacaaaaa attccaattg atgtgtgata gctctctttt
     6001 aatatagcaa ttttttgtta tataattgtg ctttttagat tacttatatc ttattttgat
     6061 attataatgt agcttaatct tttatttgtt gaaatcaact tatttatttg tataaataat
     6121 ataggttatt ttcaaatttt tttaataatt ttaccactgt cttcttttag attagggtta
     6181 gactgtgcaa aattataaaa taatactaaa tcatgtgcaa ttatttggta tggcactaca
     6241 tgtagaaaat atagataata aaattaagga ggtagtatga aggaaagggc taaaaaaata
     6301 ttagatttta ttattaaaaa taacaatgta acatcacaag aactacaaga aaggtttaat
     6361 gtttcaaaga gaactattta ttacgatatt ctagctataa atgaacaact aggaaaaagt
     6421 ggtaatataa aaaatgtaaa acacaaattt atatttgaag gtaatttatg tgatgcaagg
     6481 aaaataattt caactgaaga agataaattt ttagatagtg attacagaaa aacttttata
     6541 ttaaacaaga tattacttgg cgaaaaaata tcaatagaaa aactaacaaa tgaaatgtta
     6601 ctttcaaaaa acacagtagt acaaacaata actgatgtaa aaaaatacct tcaaacaatg
     6661 gggttaagat tagagtataa gggaaagtac aaaattatag gtgatgaata cgttattaga
     6721 gagctgtttc tgataattgt tcaagaaaat gtactggaaa ttaattctat aagtaaggaa
     6781 gtaagtagtt tcgatacaaa aggacatata aaacttactg attattcttt attaaatcta
     6841 actaagtttg tggaatttct aaataaaagg ataagagatg ggaaaacatt atactcatat
     6901 aaatatctaa atgaagctaa aaaaattagt tactttagta attgtaaaga acttttatgt
     6961 gaagaagcca atgaaaatga acaagcctat atatgcactt acataagttc acttcctagc
     7021 ttaaatagtg aagttaagga agatgttgtt gaagaatatg tagataaact tatagataag
     7081 tttgaagtaa atacagcaat aaaattagaa agtaagcatg agtttaagaa aaatatttta
     7141 aggcacctcc actcttctta caacagaata cgatttaagt ttcctattag aaatccaatg
     7201 ttagatgaga ctaagtataa acatgagtca ctttataaaa ttataaaatc aattatagaa
     7261 aatgaagaag agtttcctgt atttgagggg ataagagaag aagagatagg atttatagca
     7321 gcgtattttg gagggtattt aagagggtct agggataatg gcctaagaag aaataaagtc
     7381 ttactagttt gtcctaatgg tcttatggta tcaaagagtt tggaaataca actatataaa
     7441 tacataccaa ccatagaaat agtaggtata gtgtccatta agcaactaaa agaagtaaat
     7501 gtatactacg attacataat tacaactata gatatacaaa atgtaaacaa tgtaattgtt
     7561 gtaaatcctc ttttaacatc atcagatgtt caattactta tgaacaaact aataagtgta
     7621 aaagaaaacg agaagtattt caatcttgaa ttaataatac aagctataag aaaaaatgga
     7681 gttatcaata atgaagaagc actaaaagct gatttattaa acataataca caagatagat
     7741 gaaggagaga tgtatcaacc aatgttaaag gaattaatta atgcagaaag ggtcaatata
     7801 ataaaaagtg ttagagattg gaaagaagca ataaaaatag cctcaaagcc attgttagaa
     7861 gataactcta tagaagagtt atatatagaa aatatgataa agtcagttga aaaatatgga
     7921 ccatatattg ttttagctga tagatttgct ctaccacatg caagttctaa agaaggagta
     7981 aacaagcttg ctatgtcttt actaatagta gaagatgaag ttgatttatt aggaaaacca
     8041 gtaaatatat ttatggtatt agctgctgta gataacacta ctcacattag agcattagca
     8101 tcactatcag agatgatgta cgaggaagaa aatgtaaaac taataattaa tggtgataaa
     8161 agttcaatac tagaacttat aaataagcaa aattaggagg aatgaaaaat gaagatatta
     8221 gcagtatgtg gttttggtgt aggttcatca atggtattaa aaatgacaat acaaaaggct
     8281 ctaaagcagt taggtataga atgtgaagta gaaaatacag atataaattc agctagaggt
     8341 gctgattgtg actgtatatt cacaagtcaa gaattgttaa atgaattaaa aggaacttgt
     8401 aatgtagatg tatatccagt taaaaagtac atggatttag cagaagtcac agaagttgtt
     8461 caaacttttt taagtgataa aaatgataag aaatagtata agttttaaaa agtaaattta
     8521 agttaatcag aataaaataa aaacttacta aattcaaaaa tagtaagaaa gagaggaggg
     8581 atttagtggt agaaaactta aacagttgac ctatcactaa aaaatataat gcttgatttt
     8641 atttcaaata atattttacg taatccatct atgttaattg gattaatagc agcatttggt
     8701 cttgtactac agaaaaagaa agcatctgat gttataaagg ggtcactact tgcagctttc
     8761 ggaattataa ttatggagac tggaacaggt atgttagtta gttcaatagc accaattaat
     8821 ggagctttcc aaagtataag tggtggtgca gtaacaaaag gtttaagtga tgttactttt
     8881 actgcaagtt atggtggaat tataggttta gcaatgtttg cgggtttagc tattcaccta
     8941 atgatagcaa gatttactcc tattaagaca atcttcttaa caggtcacat gctttattgg
     9001 ttcccattca tatttgtagc ttcaggagtt gaagctggat taaatggtgg agtattaata
     9061 gcttttgcag cagtattatc agcactctat tggtcaataa tgccttggtt attaagaaaa
     9121 tatgtgtttg atgttatagg agatgattct tttacattag gtcatccatc tggttgttta
     9181 gcacttatat caggatttgt tgctaaatta gtaggaaata aagaaaaatc tacagaagat
     9241 ataaacatac ctcaaagttt atcatttttt agagaaatat ctataagtgg tggaatggca
     9301 gtgtttttaa tgtttatagt tgttgggata gtaataccag gtgcgtttaa agatagtaat
     9361 gagtttattg gaacgtatgc aataaagcaa ggtctttctt ttggagcagg tcttataata
     9421 atgcttcatg gggtaagaat gctaataaat caaataatgc cagcatttca aggtatatct
     9481 gaaaaagttg tgccaaatgc actacctgct tttgactgtc caatattatt taattataaa
     9541 ccaaatgctg tattaatagg attcttagtt gctatgctaa catctacagc tatgatttta
     9601 atatgtaact actttaatgt atttaatttg ctacttatac cacttgttat aacttcattc
     9661 tttgagtgtg gagcagcagc agtaatagga gaatcacaag gtggtatacg tggagctata
     9721 ataggtacag ctatagctgc aatatttatg gtagttttag taggaatatc tgctgtaatt
     9781 tactcaggaa ctattcaaaa ttggatacta atatttggag gtaacgacct ttcattattt
     9841 ggtataatta gtaagtttat aggttcacta tttggaggaa tattatagat atgaaattta
     9901 aatacataga tgagataaga agattaattg atataataga aaacgaagaa aaagtcaata
     9961 tggaaaaagc agtacaaatc cttgttgaag caatagaaag taaaaatgct atattttcat
    10021 ttggagcttc acatgcagga atattaacag aagaattatt ctatagagca ggtggctgtg
    10081 ttcttataaa tccagtattt gcaaaatctc taatgttaga tacagcgcct ataactcaca
    10141 caagtaagat ggaaagatta gaaggatatg gtacagctct agctgataaa actccaatta
    10201 aaaaaggaga tgtagttata gttcattcag tatctggtag aaatccagta agtatagagt
    10261 ttgctatgaa agctaaggaa aataaggcaa tagtaatatg tataactaat ttaagttact
    10321 caaaaagtgt atcttcaaga cattcttcag gaaaaaaact ttatgaagta tgcgatttag
    10381 tgatagataa tcatggtcaa aagggagatg cctgtgtaga gatagatgga ttaaaccaaa
    10441 aagttagtcc aacttctact gtaatagcaa ctactgtgat gaactctatt atagctcaag
    10501 ctactcagga attagttaat aaagggctaa agaatcctcc gattttctat agtgccaata
    10561 ttgatggtgg agatgagtta aataagaaga tttttgatga atataaaagt gtaattcatt
    10621 atgaatatta aggttaaaaa aatatgttaa tgaactttga agtttatcaa caaagaatat
    10681 taataatata taataaatgc tatcatttaa aagctgtagg taaaaatcta cagcttttta
    10741 ttattgtaga ttaaaaagat gcgtaattaa attttaaatt ggagaaaata aattggaagg
    10801 tatcaattat aaatattaga aacgttgtca tagaaaaaaa ctatattaaa aaaaagtaca
    10861 tagaaaaaac tgattagaca ataaatacat gctttgataa tattttaaat ggagtgaaaa
    10921 tgtgtagaat tataatgaaa aaagaaaata aaaatgaaaa aagaaaataa aatggaggga
    10981 ataaaagtgg gtatgttaaa aaaattatgt tcactagcta tggtagcaat tatgactaca
    11041 acacttataa cagggtgttc aagtggaaat ggaaaagatt caaaaaagga tggcgaaaaa
    11101 gaaaaactag ttctttggat gccaccagta gaaaataata tgaaggaagt ttgggaccct
    11161 attttagata aatttgagga aaaaaataac tgtgaagtag atttacagat aattccttgg
    11221 gataattatt ctgaaaaatt tgcaacagct ataagtgctg gcgaaggtcc agatgtagga
    11281 tatatgtatg cagaaatgta tccacagttt atagaaagtg gagcagtaga agatttgact
    11341 aactatgcaa ctaaagagga taaagagcaa tctatttata taaaaacatc tgaaatgatg
    11401 ggtggaatgt atggtatgcc attccaagca gcaaatccag gggtattata ctataacaag
    11461 gatattttag agaaattagg agagaaacct cctaagacat gggaagattt taaaagaatt
    11521 tgtaaaaaag caacacaaga tactgatggt gatggaaaga tagaccaatg gggattagct
    11581 cagggatggg gagctaaaac ttttggtaac ttaaactgga actggtatcc ttatttatgg
    11641 caagctggtg gagatatttt taatgatgat ttaaaatcgg ttaaatttaa tgataagagt
    11701 ggtttagaag cagctaattt cttaaaagaa ttacaagcat atgtgcctga agattcttta
    11761 tctaaagata gtaatgaaat gatagaaagc gtatttggac cagggaaagc agcatttaca
    11821 ataatgttat cttctgctgc aacaagtgta tttgatgaat cattcccgga tttaaattgg
    11881 gggtttgtaa ctggactaga agataagaaa gcagcaactt ttggagcagt agaccattta
    11941 tctttaatgt catctgctaa aaataaagaa cttgcataca agttaataca acatatgtta
    12001 agtgttgaat caatgacaga atttcataaa gcaataccaa gagcaccaat aacaaaaggt
    12061 gaaccatatc aaggtgatga aagattcaaa gaaatggtgg aaaatgacaa aaatgtatat
    12121 agaccattag tagtaggacc tcatggagtt gaaatatatg aatatttatg gaaagaactt
    12181 caaactatga tttcaggaga taaaactcca aaacaagcat tagatgatgc tgcaaaatat
    12241 tcaaatgatt tattagcaca ataaaagttt aaagctgtaa tatgttgtaa aggactttac
    12301 agattaaaat tagcattgta tttataaata caatgctaat atttatattg gagaggataa
    12361 aatggaaaac ttagttagag agtttgaaga aaattcaaaa agaaaaaaaa caaaattaaa
    12421 tattaaacca tatatgtata tattgccatt gggaataatt ttagtggcgt tttatgtgat
    12481 accaataata atgtcaatat actttagttt tacaaagtat aatattatta gtccagccac
    12541 ttttataggt ttagaaaatt ataaaaaatt atttacagat gaaacattaa aagtatctat
    12601 tataaatact attaaattta ctgttgttgt agtaccttgc caaactatat tatcattgat
    12661 tttggcagtt tggattacag gaaaaggaaa tagtaaaata gcttcatttg ctaaaggtgc
    12721 tatatttata ccagtattat catctatggt tttgataggt atggtatgga gggctttatt
    12781 gaatggagaa ggttctatta tatatcaggt attaggtgcc tttggaatag aatcatctaa
    12841 acttttagga gatagtaaga cagcattacc tacacttatg tttatatcta tgtggaaaaa
    12901 tatagggtat ttcatggtaa tttatatttc agctataatg aatttaccaa aacactgcta
    12961 tgaagtagcg aaggttgatg gggctacaaa acttcaagaa tttataaaaa taactgtacc
    13021 tttattgaaa ccaactacaa taatggttgt atttttaggg tcgatatggt cattacaagt
    13081 atttgactta atttatactg tgacaggtgg aggtccaggt atatctacta tgagtatagt
    13141 tatgcatgca tttaacttaa actttaaaaa ctttaattct ggatatgcaa tgactgtagc
    13201 aaacgtatta tttttgttaa tagcagtagt ttcgatttta caaaataagc ttgtaaaacg
    13261 agacaattca gatttttaga aaggtaggta taatatgaaa acagcaagaa gattattaag
    13321 tgatggttta cttttattta tagcgtgtgc aagtttggta ccttttatat acatgttgat
    13381 aatatcattg aagataacat ataactcata tagtttggat atatcttttt caacagtaac
    13441 tcttcaaaac tatatagata tctttactaa aaaaggattt gcacaatatt tttttaatac
    13501 agcaatagta tctttttcag gtgtattatt aaatttagta tttagtacat tagcaggata
    13561 ttcttttgcg aagatggatt ttaaaggtag tgataagtta tttttattta tgataatgac
    13621 tttaattata ccttcccaag ttacaatgat accactatat ataataatga aacacttagg
    13681 atggataaat agttatcttg cacttattat gccaatacca actgcatttg gcgtatttat
    13741 aatgagacaa gctattttag gagtaccaaa agagttatta gaatcagcaa agatagatgg
    13801 ttgctcggat tttagaattt taatacaaat agtattgcct ttaatcaaac cagcattaat
    13861 tacactagca atatttactt ttatgggagc atggaacgag tttatgtggc ctcttatagc
    13921 tacaactaaa gatgcaatga gaacattaac agttggatta tctactctta agacattcca
    13981 gataactaat tatggacaga tgatggcagg ggctacaata acatttttac ctccatttat
    14041 tttctatttg attttacaaa gtaaatttgt tgaaggtgtg tctttgtctg gtataaaagg
    14101 ttaaatagtc taatttaata acataaaaga aacttatata aatatggagg aatttaaact
    14161 atggaaattt catatgtact gaaagattgc acattcaaac acaataaata ctcagttata
    14221 gaagctgaaa cttggaaaga gaaggatttg gatattgtag tagctaaagg tgaaaaattt
    14281 gcatttcaaa ttatgctaaa agcaacagaa gaatttaatt gtacaattga taaaagcagt
    14341 actatatcat ggaaaggact ggaaaataga gtaagattag cattaaatgt gcctaatagt
    14401 ttagaaaata attttagtat aaatatatta ggatatgttc aagatgatac aaaggcattt
    14461 gtgaatgatg ctattttaag ggataaagat gtgttagtag agcaatattt gcctcaaaca
    14521 ttttggattg aaggtcaagt accagaagat tttgaagaaa ataaccttaa tataggtatt
    14581 gatatattta aaagctttgg atatgaagat gaagaaaaag tttgtacaat tgatgttcct
    14641 gtaaaagtaa gaaatgtcgt gctaaagcct ttagataaaa gcaagttctt tttagattta
    14701 tggcaacatc caagttgttt agctagaatg tataaagttg agttatggtc tgatatacat
    14761 tttgaaatag tcgataacta tttaaaagaa ttagcatctt taggagaaaa agttgcaaca
    14821 gttatagttt cagattatcc atgggcaggg caaagttgtt ataaagttta taaaaatcca
    14881 tcaaacctat atgaatataa catggtaagt gtatcaaaag gattggatgg aaagattaaa
    14941 tgtaactttg agagtatgga taggtatata agcatagctg ataagtataa aatgtctaag
    15001 gagatagatt tatttggtct attaggtaat tggtgtgctg gtgagtttgg aaatcctgta
    15061 gaaggttata aggaccctat aagagtaaga tattttgatg aaaatgataa agtatttaaa
    15121 tttataaaca atacaaatga tttaaaagaa tatataggat tagtattaaa tcatttaata
    15181 gagtgtggat tatgggatag agtaaggatt atagctgatg aaccaaataa tccagaagta
    15241 gtcaaagagt gtatagaatt tataaattct actgtaggta ctcatcaagt taaatataaa
    15301 tcagcaactc acgaccaaaa ctttttagat agagctaaag atgaaattga tgatatgtca
    15361 ataaatttaa aacttactat acaaaattat aaagatatag aaaatcttaa gaaaaaaatc
    15421 aatgacaagg gtgggatatt gacttggttt gtatgctgtt ttccagagaa accaaatagt
    15481 tttttaagtt ctccttttgt agaaaataga ataataggat ggtatactta ttactttggt
    15541 cttgatggat ttttaagatg ggactataat ttatggacag aagacccttg gaaagattca
    15601 agttacaaat tccctatttg gaaagctgga gatatgttct ttgtttatcc tggaaaagat
    15661 ttaaagccag ttagaagtgt cagaatggag aatttaagat ttggaataca ggactttgag
    15721 ttatttacaa tgttagaaaa agaaaagggc agagagtata tagaagttga gcttatgcaa
    15781 gaattattaa ataaaaaaga aaatgctgaa attaaaggtt ttggtgacat agaattagga
    15841 tattcacttg ataattgggg atatgataaa gttaaaaaat atgtattaga gttgttagac
    15901 agagtataaa aaaatataag agtgtctcaa aatgaacttt ttagttcatg aggcactctt
    15961 tttgtatgaa atcaatatag tttcattgtt tcaacaatga aaaataggat tacttatatt
    16021 ctaagatagc cctttagttt tttagttgta ttcaatgttt taaaactaac tataaacgct
    16081 ataaagttta taaatgacaa taattatatg taacatgatg tactttaatt tgctataata
    16141 gggattgaat aatattatat ggaagataac attgtttggg gggattaata taaaaagaat
    16201 aggtattatt ataatgtttt ttttaagtat agcttttatt ggattttatc ttgcaataag
    16261 aggtaacagt gatacagtta agatgcaacg agggataaat ataggtaatg cactagaatc
    16321 acctaaggat tttccgtggg atgtaaaaat gtcaaataag ttttttgatg atataaaaga
    16381 tgcaggtttt gacacagtac gtataccagt aaggttttct gattatacgt cagattctga
    16441 taattttaaa attgatgaag aattttttaa aaagattgat aaatatgtag attatgcatt
    16501 ggataaagac ttaatagttg tgttggattt acatcatttt gaagaaatta tgaaagaacc
    16561 aagagttcat aaagaagagt ttttaaaaat atggcaacag atagctaata ggtatcaaaa
    16621 atatgataaa aaattggtat ttgaattatt aaatgaacct aaagaaaatt tatcttcaca
    16681 attactaaac gaatacattg aagaagcaat aaagataatt agaaaaacta accctaaaag
    16741 aactattata gtgggaccat ataatttcta tcaaattgat tatttgaatg aattaaatgt
    16801 tccaaaagat tctaatatag tagtttcttt tcactattac gaaccaaatg attttgcatt
    16861 tcaaggaaac atttatcata atggatttga gcacttgagc aatattactt gggaaggaac
    16921 aaatgaacaa atggattatt taaaaaaaag gtttgatatt gtagaaaatt gggcaaataa
    16981 aaataaggta aaaatattct tgggtgaatt tggagtaaca aaagaagcac cagaagcttc
    17041 aagaagagct tggataaaag ctgtaagaga agaagctgaa aaacgaaact tttcatgggc
    17101 ttattgggag cttgcttctg gatttggtat atacaatcaa attgaaggga cttgggatag
    17161 agacatatta agtgcattaa tagaaaagag gtgattttat gaagaaaaat tcaaaaaaga
    17221 tacttataac tttaactatt attactaata tcgtatatat attgtggaga attttttaca
    17281 cagtacctaa agaagaaggg atgtttgcct taatctgtgc tataatactt ctttttgtag
    17341 agataatggg tatgatggaa atgtttgtac attattatgg tatgtcaaat attgagtatc
    17401 ctgaaaaacc agtcataagt gaagaacttt atccacatgt agatgtattc attgcaacat
    17461 ataatgagtc tgttgatttg gtgagaaaaa ctgtaaatgg atgtattcat atgcagtatc
    17521 cagataagaa aaaggtacat atatacatat gtgatgatgg aaatcgtgaa gaaatgcgta
    17581 ttctagcaga aaaaatgggt gtaaattaca taactagaac tgaaagagaa ggagcaaaag
    17641 ctgggaattt aaataatgca atgcaacata caaactctcc tttgattgct acgtttgatg
    17701 cagatatgat accaatgcat gactttttaa ttgctacagt accatacttt ttgaaaaatg
    17761 agcaagctaa aaaagatgga gaaaaagagg agtatgaaaa ggttggtttt gtgcaaactc
    17821 cacagagttt ttataatcca gacttgttcc aatttaatct gcactctgag ggaaggattc
    17881 caaatgagca agattatttt tacagagata ttcaattggc tagaaatagg acaaattctg
    17941 taatttatgg tggtagtaat acagttattt caagggaagc acttgaagaa gttgatggat
    18001 tttatactta ttctattaca gaagattttg caacaggtat cttaattcaa agtaaggggt
    18061 atagatgtta tgctattcca gaagtacatg catcaggttt atctcctaca gatttaaaaa
    18121 gtcttattaa gcaacgtgaa agatgggcac gtggatgtat acaaactggt agacgtctaa
    18181 atattttgtt taggagaggt ttaggttttt ggcagaaaat aagttatatt tcttcaatta
    18241 cttattggta tgcaagtata aaacgctttg tatatataat ggcacctatt ttattttctg
    18301 tgtttaatgt gattgtagta aaatgtacat tacttcaagt attggtattt tggttgccaa
    18361 tgtatatttt aagtagttta tctcttaaaa tattttctca aaatataaga aatactagat
    18421 ggaccaatat atatgaaact ataatgtttc agtctttaat gccagcagta atacttgaaa
    18481 cgtttgcaat atctaaaaat aaattttcag taacaaataa gaataaatta gaagaaaata
    18541 gaatgtataa gtttttacag ggaatacctt attttattta catggtctta tctatcatag
    18601 gaattttaaa aatgtttgta gcaatattta aaatgagttc aatgacatat tcagttgtat
    18661 tattttggtt gattggaaac ctttttaacc ttgttatggc tacattattt atatcaggga
    18721 gacaacagtt aagaaagtct gagcgttata ttgctgaaat tgattttaag ttaaagcaaa
    18781 actcttatgt tctttcttca aaaacgattg atatatcaga aaatgggttt gcatttttgc
    18841 tagaaaatcc agaatatatt tccccagaag aagagttcga ggtagagttt agagaaaaat
    18901 caggaaatga aatgtatata gctaatatga aagcaaagat tgttaatgtt gtggaagtaa
    18961 attcaaagtg gaaatatgca gcttatatta cacatattga agatagtgaa atagataatt
    19021 ggatgtgtat tgttcacgat agaataccta ctttaccgat gacaatatct aatcaactag
    19081 gtttctttga tgatttgcaa attaatgtaa aaaaacgtat tgaaaagatt agaacattat
    19141 cacgaagaag tccaagaatc aatatgaatt ttcagatgga tataaaaaat acaggtaaat
    19201 taagaatagt aaattttaat tatcaatatg tattattaaa ttttgagaat aaaaatattt
    19261 atcctaaaga aatagcattg gaaattaatg aaaatattgt gttagaatgt gatttatgtg
    19321 agggtaaaat cgatgaaaga ggtctcttat ataaagtaaa taacattgac agcataatgc
    19381 aaaatttctt tttaagagat gaaatgatgg attggatatt acaaaataag acaattcctg
    19441 tttcaaatcc tagtgaaaag aaggaaaaaa gtatagatga gtttgaaccc atggaatata
    19501 tttaggagag atgaaatgaa gactttaaaa gtgttttttt gttctgcaaa atatcttatt
    19561 ttggtgttta ttttttttat aaatactact tttataagtt cagcgacaag tgataaaatt
    19621 ttagatttat cctttaaaaa gatagagact gatttaagtt ctaggattac atatgaagat
    19681 acaggtgtaa aaatagaaac agatagttct aaaagtgata aggaacgtta tttatatatt
    19741 taccaaaata taaaagaaaa ttggagtatg tataataatt tttatattga aattcaaaat
    19801 aaaaataaaa gttcccagaa aataaattta agtatacaaa gtaagaatat gcttgaattt
    19861 aggttaaaag aaggtagtga aatatttttg gaagataaaa atataatata ttcagataaa
    19921 ataaaagaag gatgcataga agtaccaggt gaatttgaag gcaaaattta tgtgaacttt
    19981 aatagcctta taaatgagaa aagtaatgtt gtgctggact caagtatgct ttcaaacatt
    20041 gttagttggg gaattacatt tattccatct gatgaagaac ataatattgt tattataaaa
    20101 aagatatctt tattgtctga agagaaatta agttttttac ataatattaa aataactggc
    20161 aatgaagaag tacaaatacc agtattgggt caaagtataa gtcagtatga ggtattaggt
    20221 cttaaacgtg attctaaaat taagtattct cttatgggaa aacaagataa tgtgagcata
    20281 tctcaaaatg gtaaattaac attaagtaat aaagccgaac ctggacaaat tattttacaa
    20341 gttaatgttg atgataagtt taaaattgga aggaaaatag cattaactga atcttggagt
    20401 attaataaaa aagataagga tggtgttcca tatacattgg tatctcctga gcaatcacca
    20461 acagtacaat atatgaaaaa aataaacttt atgaataaca tcataacgtt tgttcgaatt
    20521 ttatttgtat ctctagtaat aatatgcttt ggaatatatt tatattggaa aaaatgttca
    20581 aaaactaagt aaagagagga ggttagattg tgttattttc aagtttaatt tttttatttt
    20641 attttttacc tataactttg gttttatatt atgtatttag gtttaaccga acgatacaga
    20701 acatgatatt gcttgctgtt agtttatttt tttatgcttg gggagagcca aaatttgttg
    20761 ttatcatgat agtttccata ataatgaact atatatttgg tttactagta gatagatata
    20821 gggaaagtaa aataaaagta aaagtttttt tagttttgat gtgtgtatat aatataggtg
    20881 ttttatttat atttaaatat ctagcttttg cgctaagaaa tattagtgaa cttattaata
    20941 ctgaactaac tatacctagt attgttttac ctataggaat ttcatttttt acatttcagg
    21001 gaatgtctta tgttatagat gtatatcgta gacatggaga agtccaaaag aatccttttt
    21061 atgtgggact gtatatagca tttttcccac aattaatagc aggtcctata gttagatatg
    21121 agagtgtggc agaacaaatt ctcaatagaa aagaaacttg gaataaattt tctattggga
    21181 cttgcaggtt tataacaggt ctaggcaaaa aagtattaat ttcaaataac atggctatag
    21241 tagcagacta tatttacact atgaatagtc aaggagaaat agctgcatca cttgcatggc
    21301 ttggttcaat agcctatact atgcaaatat tctttgattt ttctgcttat tcagatatgg
    21361 ctataggttt aggtcttatg tttggtttta aatttgaaga gaactttaat tatccatata
    21421 tatcaaaatc aattagtgag ttttggagaa gatggcacat ttctttggga atgtggttta
    21481 agagctatat atactttccg cttggaggtt ctagagtagc aaataaagat attatgatta
    21541 gaaatatgtt tatagtgtgg ttatttactg gaatatggca tggagcagaa tggacatttg
    21601 taatttgggg gattttaaac tttgttttct tgattataga gcgatttata atgtttgaaa
    21661 agattgaaaa tcacaatttt ataaaacata tttatgcgtt attagtagtt aactttgggt
    21721 gggtattgtt taggtcacct aatttaaaag aagcatataa ttatttcaaa gctatgcttg
    21781 gaggcaatgg agttatatgg agtgattata catatatgtt tttaaaagaa tactgggttt
    21841 tctttatatt tgcatttatt tttagtgtac ctattgcaaa gaaaatcaat aagtttgttg
    21901 ttgaacaagc taaatatagt atgatattta acgtatttta tccaatctca gctattttat
    21961 tgttctttat ttctgtgaca tatttagtaa ctggaagcta taatccattt atttatttta
    22021 atttttagtt gggaggaaaa gtatgaatag attttttaaa gtaagattaa taactgcaat
    22081 tatgttctta attattttat tcgctttctc tatctttaat atttgttatt ctggaaaaga
    22141 tatgatacag gagataaaaa attcagttgc tgaaaaaagt agtttaaaag atacaatatc
    22201 atctattgat aacacagtaa atgacaaagt aatatataaa aatacgttca ttgaaactta
    22261 tggctactta caaaagttaa tgggtaaaaa tgagttttca aaatttagtg ttgtaaaaga
    22321 tacttctgga aagatgcatt atacatattt tgctaaagct ccaaatccag ttggtgtgat
    22381 agcagatagg gtaagaaaat tttctgagga aatggaaaag caaaacacta aattagttta
    22441 cttaatgact ccagataagt atataaaagg agtgacaaaa tttccaaaag gaatacctta
    22501 ttcttatagc aatgagacag cagataattt tttaaatcaa ctaaaaaagt ataatgtgga
    22561 ctatattgat tttagagaaa atattttaaa gagtggtatt ccaaaagatg atttattttt
    22621 taaaacagac catcactgga aagtagaaac ttctttttgg gcatttggag aattagttga
    22681 gcaacttaat aaaaaataca atatgaattt agatgaaaat cattactata gagataaaga
    22741 aaattataac tcaattgtat atcctaagtc atttcttggt tctatgggaa gaaagactgg
    22801 tatcttatat ggtggtatag atgattttac attaatttat cctaaattta agactaatta
    22861 tacttattat acagattcta aatctcaaaa atttgaatta aaaggaaggt ttgaagagag
    22921 tttaatatta tcatatcctt ttaatgcaga ccttgattta atggatggtc aatcagataa
    22981 gtattttaca tatttattgg ggaatagacc attagttaaa ataaaaaata tagaaaatcc
    23041 agatggatta aaagtgctgt ttgttaaaga ttctctaatt gtaccaacag cagcattttt
    23101 ttcctctgtt tgttcatcta tagatatgat agaccctaga tattatgatg gagatatact
    23161 agaatatgca aaatcccatg actatgactt tgtttttata tctgtatatc cccaaaatct
    23221 tacaaaagaa ttttttccgt tttgtaagta aatttctaaa gaaattttct tataaaataa
    23281 aaaataaatg gctaactagt taaaagttag ccatttatct taagtgttac tctaagaaat
    23341 gtttttttta ccaaatactt ctttatctat ttttccaagt gattttccta cagtaattga
    23401 tgataccata gcaccattaa catttatcat ggtacgtccc atatctagta tagggtctat
    23461 tgcaagtata ccaccaacta atggaaaata agaaccaaga ccaactccag agataacaac
    23521 tgaaacggcc attgtagcag ttcctggaag accagctatt ccaaacgaac taattgttat
    23581 aacaattaac aacataacat aaaggctcat atccatgttt actccagcca tattggcaag
    23641 tgttacagcc attaaagcag gatatatacc tgcacaacca ttcataccca tatttgcacc
    23701 taaacttgct gtaaagcttg atacaccctc atcaactccg tgattttgta ctagactttc
    23761 tatcgttaca ggcaatgttc ctaaactaga acgtgaagta aatgccagaa gtaaagcttc
    23821 agttgaattt cttatataag taatgggatt tagaccattt aaagttataa aaattaaatg
    23881 tatggtaaat aatattgcca ctgatatata aagagctaat ataaactgta aaacagatac
    23941 tattgagcta ataccttgtg aagttattgt atttgcaagc agagcaacca cagcataagg
    24001 cataaattta ataacagtca tagacacact tacaattatt ttgtaagatg cttctataaa
    24061 atctataaat ggttttattg tttcaaagtg ttttttactt aatctcttta ttgaggtagc
    24121 tataaatgta gcaaatatta ttgtagctac aatatttcca tttgccatag ccattacagg
    24181 attagatggt agtaatcctc ttaaagtatc cacaagagag tttatttctt taagttcttg
    24241 attttcaact aaagtaggca tattagctcc tacacctaac ttcattatat ttgcaacgat
    24301 aattccaaca attgcagcta tagcagtagt agcaagaagc atacctaaag atttaaatgt
    24361 cagagttcca agattgttat ctttcatatt tataattact tttataatgg ataagaaaac
    24421 taaaggtact actaacattt ttaataagtc cataaatcca gaaccaaata ggctatacca
    24481 cttgcttact tcttgtagcc aagtgacttg agtggtatca ttaggaaaac cagcaaaagc
    24541 ttgtattatg attcccaata tgagtcctag tactgtagca tatattgttc tcaatgaaaa
    24601 ttttattttt ttcttttcaa attgtctaac aataaagaat gtacctagaa gtaatattat
    24661 gaaaaaaatc gttttaaaat ctgtaatcat aagaaattgt gataaaaatg aactttccaa
    24721 tattttttct ccttttattt aaaaataaat ttttctaagt ttaaatgata ccaatatatt
    24781 aaaaaaatgt caatattata tcacaattta cttaaataga gtaaaataaa ttgattttga
    24841 aaaatgtgat taagtataga aaaatagggt ataataaatg tttaaagaat ttgaattgtg
    24901 gtaagaaaat aaaaaatagc ttttataata tttgatttca aattaaaata tgttaaataa
    24961 ataactaaaa attgttatga aaaatgttta catagaatat atatcaaatg aaaagcttaa
    25021 aataagtgaa gaaattaact agacatcaaa ggagagataa aatgagagta gtaataattg
    25081 gtggtgttgc agctggtatg agtgctgcag caaaattaaa aagaataaaa cctgagtatg
    25141 aagttgttgt ttatgaaaaa actgaaatag tatcttttgg tgcttgtgga ttaccatact
    25201 ttgttggtgg tttttttgat gatgctgatg aattattagc aagaacacca gagaaactta
    25261 gagaagctgg aattgattta aatatattta gagaagtcgt tgaggttgat agtgaatcta
    25321 agaaaataaa agtaaaaaat ataaaaacag atgaaatata tgaagattac tatgataaat
    25381 tgatgatagc aactggagca agaagtatta tgcctcctat aaaaaacata aaattgaaga
    25441 atgtttctac attaaaaagt ttatatgatg gagaatatct aaaaaaactt ttaagtaatg
    25501 aagataataa aagagtgaca ataataggag ctggttttat agggttagaa gcagttgagg
    25561 catgtaagaa attaggtaaa gatgtagatg taattcagtt agaagataga atattgccac
    25621 aagtatttga taaggagatg acggatgtat tagaagaaga aataaataga cataatgtta
    25681 atttgcactt ggatgaaatg gttgtagaac tttgtggaga agataaagta gaaaaagtta
    25741 taacaaacaa aggggaaata gatacagatg tagtaataat tgctactggt gtgagaccta
    25801 ataccgagtt tttgtcaaat actaatataa aaatgctaaa aaatggagct atagtagttg
    25861 atgaatatgg aagaacttct gtagaagata tatactctgc tggagattgt gcaactataa
    25921 agaatatagt aagtaatgaa aatgtatatg ttcctttagc tactggagct aataaattag
    25981 gtaggatagt aggagaaaac ctagcaggaa gagaagtatc ttatcaaggt tcactatctt
    26041 caagttgtat aaaaattatg gatatggagg cagcatcaac tggaattaca gaaaagcaag
    26101 ctaaagattt aggcataaat gtcaaatcta aatttatttc tgattataat caaactcatt
    26161 attatccagg aagaaataaa atatatgtaa aacttattta tgatgcagat acaaaagtta
    26221 ttttaggcgg acaagtggct gggtttaagg atgctgtcca aagagcaaat gtattggcag
    26281 ctgctatctt tggaaaaatg accacaagtc aacttggaat gttagattta tgttatgccc
    26341 caccatttgc aagaacatgg gatgttttaa atgtagctgg aaatgtgtct aaataatatt
    26401 tagattatag ctaatatagt tgacaagcaa ttaagggaat gaatttacct aaactatttt
    26461 tatcatggta aaattcatcc ctaaattttt attccaaatt tttagaaata aggattccat
    26521 taaattattc atcaaaattt aaacgcaagc ttaatctatc ttctccaaga atagtatttt
    26581 caaaaacatt agtagcattt tctaaataca tactaggtat gtctaaagaa ggactaaaat
    26641 gggtcagtaa aagttgtttg acatttccaa gttttgcaag attagcagct tctctaaaag
    26701 tcatatgttt gtttctaaca gcttttgata tatctaaatc atcaccatac atggcttcac
    26761 atataaataa atcactatct tttatgaaat ctggtattga ttctataggt cttgtatcgg
    26821 ttgtaagact tatcttaact ccctttctca attctcctaa gaccatatct ggagtgtatt
    26881 gttttgaatt taaaactata ttttgacctt cttggagttt gttccataat attttaggaa
    26941 cttcgttttt agttgcctta tctatatcaa atttagggtt tcttctaaaa ttaaaactgt
    27001 atcctaaaca ctctatagag tgttctaaac tgattgttga aatttctaaa tttcttaaaa
    27061 ctttattatc taaagaaaaa ttgccttgag ggttttctat aatttttaaa gtgtatggta
    27121 catattctac taaatttctc atagaacgta tacaatcgac tattccaact ggaccaacta
    27181 tagttaaatc acttgtacga ccactattcc caattgttga taaaagtcct aaaagtccaa
    27241 atatatggtc accatgtaaa tgggttatac aaatcaagtc tatatcttta aagccacatt
    27301 tttttagctt catagatacc tgagtacctt caccacagtc aattagtatt tttctacctt
    27361 tatagtttat aaatacagag gatagaaatc tgtttggcat aggtacattt ccaccacatc
    27421 caagtaaagt taaatctatc attttttccc ctttctaaaa ttaacacaaa tctgttgttt
    27481 gtttttatta tgatatccta ttataattat tttaacatta aatataacaa taaatgtgta
    27541 tttgagtcaa gaaatattat caaataaagt ttttatatag caatgtataa aaatttggag
    27601 aacgaaaagt gaaaattata tttaggagta tttaaaggag gaaaatttaa tgaaagtatt
    27661 aaagaaaatt actattttgt cattgattac attaacctta gttggttgta gtaacggaga
    27721 agataaaaaa gtggttgaag gttctaagaa aattcaaaat tctaaaaaag atgaacagcc
    27781 tataatagta cataaagatg caaatatatt gaaagatagg tatgagccac caaaaggatt
    27841 taaaagagtt gatgtagaaa aaggtagttt tgaatcattt cttaggaata ctaagctaaa
    27901 aaattatgga gagaaagtaa agtattatga tggaagaatt aaggaatcaa aaggtattta
    27961 tgatagtgta tttgatgttg atattggcaa tagagatttg catcaatgtg cagatgcgat
    28021 tatgcttatg agagcagaat acttgtatca gaataaacta tatgatgaaa taagttttga
    28081 ttttgttgat ggttttaagg cgaagtattc aaaatgggca caaggatata gaatttcagt
    28141 aaaagatagt ggttcaagct ggtataaagc aactgaatat tcaacatctt atgagagttt
    28201 cagaaagttt atggatatag tgtttgcata ttcaggaacg ttatctcttg aaaaagaatt
    28261 ggagcctgta aaagttgagg atatgaaaat aggagatgtg tttatagttg gtggaagtcc
    28321 aggacatgca agtataatta tggatatggc agaaaatgaa aagactggta aaaaggtatt
    28381 tatgatagcc caaagctata tgcctgcaca acaaacgcaa cttcttatta atcgtaaaaa
    28441 tccaaatttg agtccttggt atagtttaga ttttgaaggt gatttgacaa tacctcaatg
    28501 gacttttaaa agagaccagt tgaaaagatt ttaaaataat aattttatat aataaaagaa
    28561 aaatatagat gtgaaaaaat gtaattagat taaaactaat tggatatgga caaaattaaa
    28621 ttgatagata aatattaaaa attacactaa tcaatcttac tatagtttaa tatttatcta
    28681 aaaagtttta tgtaaaatat aaattttata ttaaagctaa aactaatttg aggaggctaa
    28741 tttatattga agattagaag gtatttaatt ttggtaatta taattctaat tacaacaagt
    28801 cagagtttta tttcttatgg gctagagcga tttgaagaaa taaccatttt tcacactaat
    28861 gatatacatg gaagatatgc tgaaggtgat gaccatatac aaataggaaa tctagccaca
    28921 ttgaaaaaag aaactccaaa ctcaatttta gtagatgcag gagattgttt gcatggactt
    28981 ccaatagtaa atatggatag agggaaaagt gcaattgaat taattaaatg tgctggatat
    29041 gactatatta ctcctggaaa tcatgacttt aattatggaa aagatagact gtttgagtta
    29101 tctaaaagtg ctaatttagg agagaatact ttaaaatttt tatcatcaaa tatttttgaa
    29161 aatggaaaaa aagtttttga tagtaatgat ataaaagaaa tagatggaat aaaaatagga
    29221 ttttttggac tctcaaccca ggaaacaaag aacaaaactg gatttaaaaa tgtggaagga
    29281 ttagagttta aaaatcctat agaaagtgca acagaacaag taaatgaatt aaaaggaaaa
    29341 ggtgccaatg taatagttgc aatatgtcat attggtacaa atagtttaag taagccaaat
    29401 agtatagata tagcaaatga ggttcaagga attgatttga ttattgatgg acacagccac
    29461 actaagtttg aaaatggtaa acaagtgggt gatacattga ttgtaagtgc aggacaatat
    29521 ttagaaaata ttggcgagat aaaactaact ttggatacta atgatgtaga aaatataaaa
    29581 atagaaaata aatcagttag attaattgga aaagaagaag cattaaagta taagcttgac
    29641 tacgttgtaa gtaaaaaggt tgatgaaata aaagaacaac aagaaaaaat attagataaa
    29701 gttataggtg caactacaaa tactctagat ggttcatatg aaaatgtaag gacaaaagaa
    29761 actaatttgg gtaatttaat aagtgacatt ttactagata aaactaaggc tgatatttct
    29821 ttatttaatg gagggaatat tcgagatacg atagaaaaag gcaatataac aagaagagat
    29881 attgtagatg tatttccttt tagcaatact atagttacca aagaacttac aggagcacag
    29941 attaaagatg tattggagca tggagtaaaa ctttatccag aaaaaagttc agcctttttg
    30001 caagtgggag gaatttcata ctactttaat cctaaacaaa aagaaggcga aagaataaca
    30061 agtattcaaa aagaaggaaa gccattagat ttaaataaaa agtatgtagt tgcaacgaat
    30121 gattatatag cctcaggtgg agatgaattt ccttgttttt caaaagagcc aatactaaag
    30181 gaatttggaa atttagagag tgcagtcatt gaatatatag agtacaaaaa agaaatatca
    30241 aaaaatgtag atggaagaat tggtattaaa tctaaagatg agttaataag caagaatcat
    30301 gagagtgatt tgatattaag tgaaaatgaa aaaaatatca atgataatga agagaatcta
    30361 tctaataata taaaaagctc tgatagtgac aaaaataaaa gcttagataa aacaagtgct
    30421 agagaaagtt ctaatcaagg aatatctaaa agagaagcta aagaaaaatc tcctaaaaca
    30481 ggagatttag gtttttcaaa tagtataatt atatttatag tttcaagtac attgatatgt
    30541 ttattgaatt ttaatcaaaa agagttaaag gataaaaagt caaaataaaa attaatgagc
    30601 aaaattagta gatagtaatt taattttaga taatagtaaa cagcaaagga aattagttat
    30661 ataaatacta atttcctttg ttttatgctt taacatgatt atttttaaat aaaattgtat
    30721 tttatgaaaa ataattacac taaatggcat agtattatgg ggatttttag tttttattca
    30781 agtaaatgaa atcatattaa caacttctga tatatttaca aattgataaa aaaatgattt
    30841 tattagtatg atataattta gctagtatat atgatgatgg aggatatagg gatgaataat
    30901 atattacttt tggaagatga caaatcttta aatagaggaa ttagttttaa attaaaaaaa
    30961 gaaggataca atgtttttag tgcatttggt atagaagaag caaaaaatat tttcgcaaaa
    31021 gaagagatat gcttaattat ttccgatata ggtctacctg atggtagtgg ttttgacttt
    31081 tgtgaggaga ttagaaagaa aagtgatgtt tacataataa tgttgacagc tcttgatgaa
    31141 gaggtggata ttgtcacagg atatgattta ggtgcagatg attatatcac aaagcctttt
    31201 agcttgatgg tattaatatc aaaagtgaat gcgcttatga aaagagtaaa tacagtaaaa
    31261 aattatactc tattagtttg tgatgattta ttcttttatt atatagaaaa taaattaatt
    31321 ataagaacag atgataagga agaagagata attttaagta agacagagac aaaactatta
    31381 aaatatttga tggaaaattc tatgcagaca ttgactaaag aacaactgtt agaatcttta
    31441 tgggatagta gtggtaattt tgtagatgat aatacgattg cagtaaatat aagaagactt
    31501 agacaaaagg ttgaaaaaaa tccatctgaa cctaaatata taaaaacagt aagaggggtt
    31561 ggatatatgt ggggagaaag gagtataaaa aaatgctaaa aaatatgaac ctcaaagatg
    31621 gtttaagtgt gaaagatgat tatataatga gaagagttat tgtatattct gttttatctg
    31681 tactaatagt aacccttgta tttatacttt ttgaatatag cagattacat aaattgtatg
    31741 aacatcaaat aaaaaatact caaaatattg ctggaatatt gattgaaaaa tatcctaatg
    31801 atgaaataga tatagtaaat tctatttata attccgatta tagtaaggtg tctactggag
    31861 aaaaggcatt taagaaattt ggctatggat tggaaaataa aatgtcaaat gataaaaatt
    31921 ttagtttata cttaaaatct ttttttaagg aatcattttt tattttttta atgatgttta
    31981 tagtagttat aggtataata tattatttta taagatacat aaataaaaga ttgagtaaaa
    32041 tttattttat agtagataag atggcacaag aaaactactt gaaggacact actgagtcag
    32101 aagaaactgg ttatctagta gaatataatg agtattttaa agaaggtaca tttagtaaga
    32161 taaataactg tctatatgag cttaatagaa gtttaaagat aaagtttatt aaattagaaa
    32221 aagaaaaaga aagtgtaaaa tcattagtaa cagatatttc tcatcaatta aaaactcctt
    32281 tagcatcctt aaaattatac aatacattac ttatagaaga aaaattagaa gaagatgaag
    32341 ccaacgagtt cttattaacc aataaggctt ctataaataa attagaaaat ttaataaatt
    32401 ctttagtgaa catatcaagg ttagaaatta gcatgataaa cataaaaaaa gaagataatg
    32461 atataaaaaa tactattcta aatgcagtaa aaagtgttac ccctaaggct aagagcaaaa
    32521 gtataacatt aaatttaaat gaatttaaca gtagaattat accacatgat aaaaagtgga
    32581 ctgaggagag tatttttaat gtattagata atgctgtaaa gtacacacag gtaaatggag
    32641 aaataaatat atctgtagaa gaaactgcta atttctttaa aattataata gaggataatg
    32701 gcatagggat tgaaaaaaat gagtttaata atatatttaa acgtttttat agaggttctg
    32761 ctgatgaaat tgaatctgta gaaggtagtg gggtaggatt gtatttaagt agaaagattt
    32821 tagaagaaca aggtggaaat attatagttt cttcaaaagt agggataggg agtaagtttt
    32881 ctttgtttct tacaactatg taatattaaa tgaaaggaaa atgtaagcct ctacatttat
    32941 tatataagta taaacagctc cagaaataaa aaattaataa aatatggggt aatataactt
    33001 agaatgaggg gataatttta tgaaaatact atatactgaa aatttatcaa agcattatgg
    33061 aaaaggagaa aacttagtaa gagctttgga caatgttaac ttagaaataa atgaaggtga
    33121 atttgttgca ataataggaa aatcaggttc tggaaaaagt acacttttac atatgattgg
    33181 aggtcttgat atacctacat ctgggaaggt gtatatagat aataaaaata tatttacatt
    33241 aaaagaagaa gaactagctg tgtttagaag aagaaaaata gggtttatat ttcaaagcta
    33301 taatttaatt ccatctctta atgtatggga aaatgtagtg ttgccaatcg gtctagatgg
    33361 tagagaagta gatgaatctt ttataaaaga acttttgaaa tcattaggac ttgaaaataa
    33421 acatgacgtt ttaccaaata cattatcagg tggtcaacaa caaagggtgg caatagcaag
    33481 agcattagct acaagaccag ctataatact tgctgatgaa ccaactggaa acctagattc
    33541 taaaacatct gatgaggtta tgagtatatt aaaatctatg tctaagaagt acagtcaaac
    33601 tctagttatg ataactcatg atgacagtat agcccaaatg gctgatagag ttatattcat
    33661 agaagatggc agggtgtcaa aggttggtga taaaaatgat taatactact aaaatagcaa
    33721 aaagtaattt aaaacaaaat aaatcaaaaa gtattctaat aataatcact ataatacttt
    33781 ctactttaat gctttcttct attggaattt atattgttga tgcaggagca tatcaaaaag
    33841 aaaatactat aaagtattca ggtaattatc aaggtatatt agcaaatgta gatgaaaaac
    33901 aggctgatat attgagtaat catgcagatg ttgaattaac tggtgaaatg aatggagtag
    33961 gtgttgaaaa actggaagat gattcaaata tttctctagc atacatgaat gaagatgctt
    34021 tgaaattaaa tagttttgaa cttatcaaag gaaaattgcc aacaaaagag aatgaaattg
    34081 tgttagatag tggagcttta aaggcacttg gttataaaaa taaagactta ggtgaaaaga
    34141 taaaaatatc ttataatgac tataaaaatg ataaaaaaat tgaaaaagag ttcgttataa
    34201 gtggaatctt aaaaactagc gaaatatctg aagcaggtaa atattattat gctattatat
    34261 cagaattata tatgagaaat actagagata tgtcacaaga agattttaat atttatgtaa
    34321 aatttaatga taaaagtaat ttatcaatag agcaagcaaa agaaaaatta gataaaattg
    34381 ctaatgatat aggacttgat actattaata ctgctgtaaa tgaaaattat ataaatgctt
    34441 taaaaccaga tatggaaacg attatgggtg gaggttttgt aggattagta attgtattat
    34501 ctagtatttt agtaatatac aatatatttt atatttcaat agttacaaaa gttcaagaat
    34561 ttggaaaact tagagcaatt ggtgcaacta agaaacaaat aaaaaatata gtgtttaagg
    34621 aagggtttat attagccgga atagcaatac caataggaat aattttaggc tatgtacttg
    34681 caaatattat aataaaatca tttatggata tagatgtaaa atcatcacga ttaccagtta
    34741 tattatcggt tgtggtaata agctttatat ctgttgtttt atcactttta aaaccaatga
    34801 aagtagcatc aaaagtatcc attgttgacg cagtaagata tacaggaaat aaaataagta
    34861 ataagagtaa gagaaaagga tataaaaata taaatctaaa gagattatca catgccaatt
    34921 tagaaagaaa taaaaaacgt acttacatga cattggcatc acttatactt agtggaacta
    34981 tatttataac agtatcaact gctttagaaa gttttgatgc tgagaaaatg gcaagagaac
    35041 actttcctta tgatatagaa gttagactat ctggttatga aatgaacagt gataaaaatc
    35101 ctaaaaataa tttgaatatt ttacaaatgg ataatcctct aagtaaagat ttttttaatc
    35161 aaataaagaa catggaagga attaaaagaa tagaatctgc aagaagtgta aaaattggta
    35221 tggaggacta tgatgttgaa tttaagtatg accttttaca aagtataaat gaaaatgatg
    35281 taaaatcatt aaacaagaat ctaatagatg gaaaaataaa tcttgaaaga ctgcaaactg
    35341 gagatgaaat agtaattact catgttgata cagcaaaaga aatgggagta aaagcaggag
    35401 ataaaataag attaacttta tatgatggag ataaaaagat aaaaaaagaa tttaaagttc
    35461 aagcaatagc tatgggggtt ccaagttttg gtatagggaa ggattttatt gatagaactt
    35521 taaaatacga ttcaactagt agcttgggaa tatatacaga agaaggaaag tatcaagaaa
    35581 tcaaagatag tatcaagaag attgctaaaa ataatggatt tttagagact gattttatag
    35641 atagtagaat tgagtcaaat aaggctgtta tttcatttat aaagataatg ggatacacgc
    35701 taacaggcat aataggtgtg attggattta tgaatcttgt caacacaatg ataactagca
    35761 tagttactag aaaaaaagaa cttggtatgc ttcaagctat tggtcttact aataaacaat
    35821 tagtgaaaat gcttaattca gaggcaatgt attacacttc tggaatgatg ataggaagta
    35881 ttttatttgg aggtatatta gggtatattg ctgttatatt tctaaaaaag actggattat
    35941 cttatgcaac atattctttg ccaatagtac caatcttgtt gatgattgtg tgtattctta
    36001 tagctcaatt tataacaact tatttgatag gacgaagttt taataaagaa tctcttattg
    36061 atagagtaag atacagtgaa taaaatgcaa atatttgtgg ttagtttaac tagcaaaaag
    36121 catataaaaa atatagttaa agagattcat aattaaatag gttaaagcat agtacagagc
    36181 aaacaattta aacggatgtt tgctctgtat tttattatgt aatcaataat atatctaata
    36241 tactgatatt attcatgtta gaaaatgtat cggtacaatt ctaaaaaagt ataaaattgt
    36301 accatataaa atgaaaattt tgtataataa tcgtatagaa aataaatagg agctgatata
    36361 tatgaataag aagattaatt atgcaccagg accaactgaa actagggaaa atgtaagatt
    36421 agcaagagca gaaaaaacaa caaatccaga tatagatatt gattttgttg aattttataa
    36481 aaagacatgc gagaagtttg gcaatatagt tggaacaaaa aacgatgttt acatattgag
    36541 tggtgaagga atattagggc ttgaagcagc atgtgcatca cttaccgaaa aaggagatag
    36601 agtacttgta attgacaatg gtatatatgg agaaggtttt aaagattttg taacaatgta
    36661 tggtggggag tatgtgcttt tttcaagtga atatactaaa agtatagata ttgatgaatt
    36721 gaaagcattt ttagatgagg atagtaattt taaatatgca acagtagtgc attgtgatac
    36781 tccaactggc gtattaaatg atgtaagcaa aatatgtcca ttacttaaag aatatggaat
    36841 attaactgta gttgattctg tagcaggtat ggtaggagaa agattaagtg tggatgaatc
    36901 taaaatagat ataatattag gtggttcaca aaaagctatt tctgcaccag caggacttac
    36961 tatagttgga ataagtcaag atgcaaaaaa ttgtataaaa aatagaaaaa ctgatgtaat
    37021 aggtttttat tgtaatttaa atatatggga aggctattat gaaaaaaaat acttccctta
    37081 tacaatgcca ataagtgaca taatggggct tgataaagca cttgataata tattagaaga
    37141 aggaatagaa aatgtattag atagacatga aaagatagct tatagtgtta gaaaatctat
    37201 tgaggaatat ggtctagaac tatttttaga agaaggatat tctaatacag tcacagctat
    37261 aaaaattcct gaaagtatag gagctttaaa acttactgat tatatgctta aaaattataa
    37321 tacacttgtt gcaacatcac taaatcaata tatggatact attttaagaa taggtcatat
    37381 gggagagaat gcaaatctaa ataaaataga gcatgtacta aatgtcttgg ataaaagttt
    37441 aagtgcatta ggattcaaag gaaatgaaaa tttgttgaat ttatttaata agtattattt
    37501 ttaatagata gggggatata gtatggaagt tacagctaag caaaaattta caacgaaaga
    37561 catggtggaa acctcactat taatagcatt agtatttatt gcaactaaat ttataaatat
    37621 aagattacca atatctataa atggtgggct tgtgcattta ggaacagcaa tgttgttcat
    37681 atcagcaata gtatttggaa gtaaaaaagg tgctttatca ggagctattg gtatgtcact
    37741 ttttgattta atatctgggt ggactttatg ggcaccgttt acctttatag ttagaggagt
    37801 tatgggttat ttacttggaa agattgcatg ggcaaatggt aataatggga ataatttttt
    37861 aatcaatgta ataggaatat gtgtctcatc aatttggatg ttatttggat attatataac
    37921 agaagttata ctttatggta attttatagt acctcttact tcaataccag gtaacttaat
    37981 gcaagtattg ataggtctta taatagcgct tcctatttct aaggtattga aaaaatgtat
    38041 aaaataaata taaagtgaac taaaatttat gatagcataa attatactgt ataatattaa
    38101 gatggagtac ataattaaaa aattttagta tagaggttag ttcacaatgt tatcagttac
    38161 aagatattca atcaaaaatg ttcgtttaaa gccgtgggta aagtttattt ggtattttga
    38221 aacaaaatca aatatactgt taaataataa gttacttcct acagacagta tagatattat
    38281 tcttaatctt tctgatgtta tggaatataa aattgaaaat caagactata ctgctagtaa
    38341 tatgcatttt aatggaataa gggataaaca tggatttatt attcaacatg gaaatatacg
    38401 tgttataggg atttcttttt atccatttgg tctctatcca tttttaaaga taccaatttc
    38461 agagtttaac agacaaattg ttgacttaga agcagtatca gaactatttg ccaaaaaatt
    38521 ggaagagtca ttaaatccaa cacaatcagt agaaaaaatt gttttatatt tagaagaaat
    38581 gttattatcc atattagaag aagatttaat ttcaaataaa tctgtaaagc ttctaaattc
    38641 atttatatat gataatagat atagcaatat aaaagcattt tgtgataata caaatataaa
    38701 tattaaaaca ttggaaagaa tctgtttaaa atatacaggg tatacaccta agattttaaa
    38761 gagaatttac agatttaaaa tggcaagtag tcaacttatt tataattata aagataatga
    38821 actttttgat tttatttatg aaaatgagta ctatgaccaa gcacacttta taaaagaatt
    38881 taaaaaattt tcagggacgt caccaattaa atttattggt gagaataaga cgattaaaga
    38941 aaatataaag tacaactatt tataattata ctgtcgattt tttacaatac ctccaattta
    39001 ttttttgata tgatatagga aaataaattg gaggttttac atatgaaaat tattacagaa
    39061 atagttgagt ttaatgtgga agaaaattta tcaaaagaag agtttataga aattgtaaat
    39121 gacttagaat taaaatttca ttctattcaa tctggtttta ttgatactga gcttttatat
    39181 gatgaaaagt ctcaaaagtg gattatgata caacattggg aatctataga agacctcaag
    39241 agtgcttcta gtaaaatgtt taaagattct tcaactgaga aatttagaaa agctttaaag
    39301 aatcaaactg ttaagatgaa tataatacca caaattaaaa gttggaaatt atagaactga
    39361 atgtaaaaga tagttaaata gtatcaaact aaattagcca aataacattt tgtatttaaa
    39421 ttgttatttg gcttttagtg tttactttaa tatgagtgtt atatactaga aaaaccaaca
    39481 aactgttaga gtgtggatta taataatgtc atatttggga gctaaaaggc ttaatactga
    39541 tttgtcaata tgtcttttta gcatgttgaa caggtatatt gccatgcttt cattatttta
    39601 tttttttgcc ttatactgga ctacatttgc agtttcctaa tatatttggc tcatatttaa
    39661 atgccattat ctaaaagtac tattgctgta cgagaggcaa taggcatttt agaagaagga
    39721 ggagttgagc taaagtatac atcataatct cttaagtttt ctttttttgt gtttcctcca
    39781 aactctacca tatcagtatt taatatcgtt ttgtagtttg tattttgaaa ctttgaaata
    39841 tcaactgatt gtattagatt agggtggaaa ttaaatataa ataaatattt gcccttactg
    39901 tacaccaaaa tctttttatc attatccata tgtataagtt catgactatt ttggataaaa
    39961 atatcactgt attttgtaag ttcgagcata gatttatcaa aatttaataa ttgtttatac
    40021 tttaagttgt tatcttctga aaggctccat tgtcttctgg catacttata gctccaattg
    40081 ttgccttctc gtggaaaatc aatccactca ggatgtccaa attcatttcc cataaaattt
    40141 agatatcctt cacctgctag agaaaaagtt attaatttaa ttaatttaat aagagatatt
    40201 gctctattga taacatggtt atttgagttt atttccatat tccagtacat ttccttgtca
    40261 gctagccaaa aaataattgt tttatcgcca actaatgctt ggtcatggga ttcacaatat
    40321 cctatatttt tttctccagg tcgtctagta gtaagttcat accacatttt tcccaaatcc
    40381 cagtcttcat cagataagtt agagatagtt tttatccaaa aatcaggtac tcccattgcg
    40441 agtctatagt caaatccaat tccgccgtct tttataggga tacacatacc aggcattcca
    40501 ctcatatctt ctgcaatact tatcgaatta ggtttaattt cttttattaa ttcatttgca
    40561 aattggagat atgttatagc ttcaatatct gtattcatac taaaatattt ttcataacta
    40621 tcaaatgaaa ctccaagacc atggttatga tataacattg aagtcacacc atcaaaccta
    40681 aagccatcaa aatggtactc atttaaccaa aattttatat ttgaaagcaa aaaatgtatt
    40741 acttcaggtt taccatagtt aaaaagtttt gtaccccaag caggatgatt tccctttgaa
    40801 cctgagtgga aaaattgatg ttcacttcca tcaaactcat ttattccttc taaagtattc
    40861 tttacagcat gagaatgaac taaatccaat aaaacagcaa tccccattga atgagcagtg
    40921 tttatgaggt tttttaagtc ttcaggagta ccaaacctag atgagattgc ataaaagttt
    40981 gaaacttggt atccaaaaga tgcataatat ggatgttcca taatagccat aagctgaatg
    41041 gtattgtatc cagctttttt tatcttagga agtatttttt cagtaaattc attataagtt
    41101 ccaatagatt cgctttcagt agacatacct atatgacatt catagattag tggagaagtt
    41161 atgtttttta agtcaaaatt attgtcagtc cagataaatg gagtttttgg ttgccatatt
    41221 tgtccattaa atccaccaaa atctttttga attactcttt ttatatataa tggtatacgg
    41281 tcaaatgttt ttccatttgc agtaacttgt acctttacct ctgatttgtg aggtaagcta
    41341 ttttgaccag gaataaatat ttcccaatta ccagacccaa tttttcttag aggatgagat
    41401 tttctattcc aattattaaa gtcaccaatt agtgacaaac tatctgcatt tggagcccat
    41461 tccctataga agaatccatc atttgtctga tgaaatccat agtaaagatg agcatttgca
    41521 aaagaactaa aatctttata gtttttcaat gtttttgatt tcatatcctc ataatgtttc
    41581 attcgctttt ttatatcaga ttcaaatggt tgtaggtata catcaatatc taaaatttta
    41641 aatctttttt gacttttcat tgtatttctc ctccataata aatattacat ttaaaaaata
    41701 atatttatct catactatct tctctgtata attgatatat attatataat cctaataaaa
    41761 agcttaagcc accaatgatt aatttcataa tttacctccc tagtatttat acttatatat
    41821 cgtattcatc aaaatttaaa agtttgttta aaactctttt aataatatca taatcaaagc
    41881 ctttatagga aagatgttga gaaatttttt gatatatttt ctttttatct tctttcttta
    41941 ctctttcata cctttttttt gctagataca tagcattttc aaattcagtg tccttgtcta
    42001 attcagatac tgcttcattg attgtacttc tattgatacc tttattatat aaattctgct
    42061 taattctgtt tttgccacat ttatttaggt taacatttgt gttaacaatt ttttgagcta
    42121 atacactgtc atttacgaga ttataacttt taagaaaatc tatgaccctc tcaattatat
    42181 tttcatcaaa ttctgatgat agtttttctt ttaatttttt ttcagattgg tcagcatgag
    42241 ataaaatatt taatgcttta tttttagctt ttatatacat ttcatcatct aaaataggtt
    42301 ttaattcttc ttcatttatt tcattccctt tttttaaatt aaatgtataa acaagttctt
    42361 taaatatagc aataaaaaat ttatcatcta cataaatatt aactctatca tcatttcttt
    42421 tttgttgttc tatttttgta attataccca taagtcctcc ttttttatat gtaattatat
    42481 taacaaaagc aactaataaa atttaacaaa aaacttatat ttgtatgtta tattttatca
    42541 aaattaagac aaaatagtaa aaagttattt ttattaaaaa gtaaagcaga atcatgttaa
    42601 ataattattt tttaaagtgt tttttagcat ataaatataa ttatataccc aaaaaaacaa
    42661 attataagct ttaagaaata aaaaataatg gtacaatagt attataacat taaaaggaga
    42721 caaaatatga gaagtgaaaa tctagttaag atggcagagt tgaaaaatac tgaaaaacta
    42781 gagaaattta atcgccataa aggcaaaatc aaaataggta tattgggagg tacttttgac
    42841 cctatacact atgctcattt agcaacagca gaatttatta gagacaagta tgacattgac
    42901 aaaataatct ttataccatc aggaaatcca ccacataaat tatgtatcac tacagataag
    42961 tatgatagat ataatatgac acttctagca actgaaagca acgaagattt tttagtttca
    43021 aaagtagaaa tcgaaagaaa gaaaaggact tatacaatag atacattaaa atacttaaag
    43081 aaaaaataca aaaatgcaga catttatttt ataacaggtg cagatgcaat ttgtagtgtt
    43141 gaagagtgga aagatgtaaa gaaaaacttt gagttagcta cttttatagc cgcaactaga
    43201 ccaggaatta gtttgttaag gtcacaagag actatagaaa aactaactaa gaagtataat
    43261 gctgacatta taacagttta tgttccatca ctggatatat cgtccacata tataagggaa
    43321 cagctaaatg aaggcaagtc aatacgttac ttagtacccg aaaatgtaga aaattattta
    43381 tatgaaaata aactatatca atatggagat gattaaatga acttagaaaa tattaaccaa
    43441 agactaaatc aaatgctacc agtggggagg cttagccatt caagaaatgt tgcaaaatgt
    43501 gctgaaaaat tatgtgagat ttatggatgt gacaaagaaa aagcttactt agcaggaatg
    43561 attcatgatt gtgcaaagta tttaagtgac aaggaaatag aggattatgt aaataagtat
    43621 gaaatatatt tagacccaat agaggatgga aatcgttcct tgtctcatag tgtaattggg
    43681 gcgtacatat gcgagtatga atttgaagta gaagatgaag atattataaa tgcaatcaaa
    43741 tatcatacaa cagggagaga ggacatgtct cttttagaaa aaataattta catagctgat
    43801 ttaattgaag aaggaagaaa atttccagtt gtagatacat taagagaatt agcatatgga
    43861 gggaagcttg atgaagcact tttaacttct tttaataata ctttaatgtt tgtcatcaat
    43921 aaaaaagaag agatacatcc aagaacagtt atggcaagaa actatctaat taaagaaaag
    43981 ttattataaa aaagctatat aaaggcaaac atattaataa atttaaattt gactatgtta
    44041 caaaatcgta ttaatatgtt acaataacta agtgtatttt aattaggaaa gtgaggaatt
    44101 tttatatgac agtggaacaa atgacaaaaa tagcatatga tgccatagaa gataaactgg
    44161 gtcaagatac agttataata aatataggaa aagtttctag tttgtgtgat tattttatta
    44221 ttactacagc atcttctcag agacaggtaa aagctattgc tgacaatgtg gaagatgaat
    44281 tagcaaaact aggattagag ccaagaggta aagaaggaca aggaactcaa acttgggtac
    44341 tccttgatta tggagacata atggttcatg tatttaatga ggaaaataga gggttttata
    44401 atttagaaaa attatggaaa gatgcacctt atatagatat tgacacatta gcataaacat
    44461 gataatatat gttattataa ttagaaaatt tcaaaaatta tattaaattg aatagactag
    44521 agcagtaaaa gattatattt tttcagagag ttagtggaag gtgagaacta atattatata
    44581 actttgaact tactagatta aaatctattc tccatggctg gattaaaagc tatctaagag
    44641 agtctatata tgtagtaggc taattagggt ggtaccgcga agatttatcc tcgtccctaa
    44701 acgtaagttt agtgacgagg attttttatt ttcaaagaat tatttggaaa ttataagtaa
    44761 ataatactaa ataaggtagt tatacacaat taaaaatagg aggcaaaata tgagcgtata
    44821 taattttaaa gaagtagaat cgaaatggca aaaaatttgg aaagataata atcagtataa
    44881 aatggatact gcacaaactg aaaaacctaa ttattacaca ttagaaatgt tcccttatcc
    44941 atctggaaaa atacacatgg gacatgttag aaattattct ataggtgatg ttgtcgcaag
    45001 attcaaaaaa atggaaggat ataatgtact tcatccaatg ggatgggatt cttttggatt
    45061 accagctgaa aatgcagcta taaaacatgg aatacatccg cataaatgga caatggaaaa
    45121 tatagaagaa atgaaagagc aattaaattt attaggtatt agttatgatt gggataaaga
    45181 agttgcaact tcaactccag aatactatag atttacacaa gaaatatttt tgaagttttt
    45241 agagcatggg cttgcatata agaaaaaatc atatgttaac tggtgtcctt cttgtgagac
    45301 tgttcttgca aatgagcaag ttgttcaagg agcatgtgag agatgtaaag caacagtatt
    45361 aaagaaagat ttagaacaat ggtattttaa gactactgaa tttgcagaag aattacttaa
    45421 tgacttagat acattagatg gatggccaga aaaagttaaa acaatgcaaa aaaattggat
    45481 aggtaaaagt acaggagcag atttagtttt tgatatagat ggaactgata aatctatgac
    45541 agtatttaca actagaccag acacaactta tggagttact tatatggtac ttgctccaga
    45601 gcatgaatta gttaaagaat tggttgcagg gactgaatat gaagcagatg ttgaagcttt
    45661 tgttcaaaaa atgcatacta tgacagaaat agaaagaaca gcagctgatg tagaaaaaga
    45721 aggaatgttt ataggtagat atgttataaa tcctttaaat ggcaagaaag ttcctctatg
    45781 gatagctaac tatgtattag ttgagtatgg aacgggtgct ataatggcag ttccagcaca
    45841 tgatgaaaga gatagagatt ttgctgaaaa atataattta gacataattg atgtaataac
    45901 agaagataac aaaatgataa attcagaaga atttaatgga ttagatgctt cagaaggatt
    45961 tgaaggaata atcgataagt tagaaaaaga aggtagagga aagagaacaa ttaattatag
    46021 acttagagac tggttagttt caagacaaag atactggggt tgtcctatac ctgtggttta
    46081 ttgtgatgaa tgtggaatag ttccagttaa aaaggaagat ttaccagttc ttttaccaac
    46141 agatgttgaa tttactggaa agggagaatc tccacttacg acttcaaagc aatttatgtc
    46201 aacaacttgt cctcactgtg gaaaaccagc tagaagggaa gttgatacta tggatacatt
    46261 cgttgattct tcttggtatt tcttaagata tgtggatagc aataatgaaa atgaaccatt
    46321 tagtaaggaa ttagttaata gatggcatcc agtagaccaa tatataggtg gagtagaaca
    46381 tgctataatg catttgcttt atgcaagatg gtttgtaaag gcatttaaga gtatgggaat
    46441 ggtagacttc aatgagccat ttaaaaactt acttactcaa ggaatggtac ttatggatgg
    46501 ttctaaaatg agtaagtcta aagggaatac agtatctcct atggatataa tagatgagta
    46561 tggagcagat actgcaagac ttttcgtatt atttgcagca ccaccagaaa gagatttaga
    46621 ctggtcagag caaggtgttg atggatgctt tagattctta aatagggttt atagattggt
    46681 tgacgagtta gcagatgtgg ttaaaaagga tgtagagttt ggagaattaa attcccaaga
    46741 taaggatatg agatatacta tacactctac acttaaaaaa gttactgctg atttaagtga
    46801 aaaattcgga tttaatactg ctatatcagc tcttatggaa ttaataaatg atatgtataa
    46861 atataaagag ttagataata taaacgaagc agttataaaa gaaggtgtac aaactatagt
    46921 aactataatt gcaccatttg cccctcattt aggtgaagaa ctatggacta tgataggtaa
    46981 agaaggaagt gtatttgata tagactggcc taaatatgac gaaaaagctt tagtaaaaga
    47041 tgaaatagaa gttgttgtac aagttaatgg aaaagttaga ggaaaattaa ctgttaactc
    47101 aaatatatct aaagatgaga tggaaaaggt agctttagaa gatgaaaaaa taaaaggatt
    47161 agttgaaggt aaaactatag ttaaagttgt agctgtacct aaaaaattag taaatatagt
    47221 tgttaaataa ctcaaaaata tgaacaaaaa tataaattta taaaataaat gaggctgtct
    47281 caaaatagag ataagccttt tttcattgtt gaaattacaa aaatagattt gattttatac
    47341 aaaaaaatga ttaaagaact aaaaagttca ttcttataca ctctaattgt tgttttaaat
    47401 attattataa ttaatgttaa atcgtgttaa tgtattaagt ggtatgtaaa ttattcagtt
    47461 tctaaagtgt tgttcatcaa ggaactgctc taagcttaaa cgaaaaaaat ataattattg
    47521 tatttttaaa atttttttta tataatgaaa acaggcaaaa aaggtgcgta tctatgcttt
    47581 atcttaaaca cccagacaac gagattcaga ttcatataat aactaccatg tttctaaaaa
    47641 ggaacttgca aaaaagatag gcgtttcaac ttcccagttg attaaaatta tcaccaggaa
    47701 aacaaggatg gtcagcagta gtattctaat gggtgttgct gatatatcca agttgggatt
    47761 gtttgaggat gttatcaaat gacttgtgat aggtgcagta gatgtggaga ttcctgatac
    47821 ggatttattc tcaggggatg tttgcttcag gagatatgga gcgtaaccag tttattgata
    47881 tggtaaccat ttttttgtct aatttgatga aagaatccca agaataccat acagaagtaa
    47941 gacaggaatt aactggtggt ataaactgat aaaggcaaat ttaaaaattt tgataggatg
    48001 attttaagat ttatcttcta ttttgttttt tagaaataat tgaaatgtta tgagggggtg
    48061 tgtacaaatg gagactgtat caaataatca atcaagtgta gaaattcaac tcagtctgtt
    48121 tgaagctatc aaagatttat tgttaattaa tcctattttc ttgttgggaa ttatcttgat
    48181 tggtattttc ttagttgtaa tattcaagaa aaatagtgat attccaaagg taaaaacatc
    48241 tattttatca ctggcaatgt attactactt atgtttaaca ctatcgcata ttgttggtat
    48301 ccctacattc agtgaatata taagactgtc acagttaggg gaaacgttct ttaatccaaa
    48361 cataaatctt attcctttta gtgatggatt tagtttgagt tttattttga atattttact
    48421 ttttgttcca ttaggttttt tatgtccgct tatcagcaaa acctttgaac ggttgagaaa
    48481 tacattcttg attggttttg gattatctct ctttatcgaa actattcagc tttttacgtt
    48541 acacagagca accgatatag acgacttact cacgaatgta attggaacaa taataggcta
    48601 tttctgcttc aaactgattg ctaaattgcg aattgtaaaa ctacattcag atgatgactc
    48661 tatggaacag gattacacag tatgtattcc gattgccatt ataatagttg cccttatatt
    48721 aggatttttt agttaagttc caaatagcta atttgggaat ccagacaata taacagatag
    48781 tatgttacct tttacaggag catactgtct gttatgttgt caacatctca ttttatggtt
    48841 tgtgtgtatt ttcttgtaaa ctgaactaaa taattaaata gaagttatta gaattagcaa
    48901 tagattcctt tttcaaagaa atctttgatt tcatcaaggt tatcagtttt tccaagtgct
    48961 aagataagtt ttattctagc tttttgacct ggcaagtccc caccaaatat acaaccaaga
    49021 ttttttaaat ctctaccaga accaaagtaa ccataactat cgaatactct acctgaatga
    49081 catctagaaa ctataactac aggaagtcct ttttctctag catattcaac tccagaaagc
    49141 atttgaggag gaatattacc tatacccatt gcctcaataa ctataccttt ataaccacta
    49201 tcaacagcaa atcttataaa gtcagcattt tctcctacat atgctttaaa taaggcaact
    49261 ttagattcta ccttatcagt atctataatt gttctattta caatatctct tgtaaggaca
    49321 agttcgttgc agtcaattat tcctaatgga ccactagtta gagatttaaa tgtatttaga
    49381 gaaagagtat ttgttttagt agcttcagaa gctaataata cttcattgtt taaaactaca
    49441 aggactcctt ttcccatagc atctttggat actgcagtac aaactgatgc agataaatta
    49501 cttgaaccat catatccaag ttcagaacta cttctcatag cacctgtgac tattacaggt
    49561 ttgatgttgt caattgtaag gtctagaaaa taagctgttt cctctaaact atctgtacca
    49621 tgtgttatta caacacctgt aatatctttt cttgctaata aatcatttac ataatttttc
    49681 aattccatca ttctataagg tgttatgtga ggtcctggaa tttcatcaaa attaaaaact
    49741 tcaacatctg caactttatc aatgttggta accattgata gtatttgttc acctgataaa
    49801 gttggtatag ctgctccgac tttatcatct actgtcatag atatagttcc accagtaaaa
    49861 actatggcaa cttttttctt aatactcata cgattctctg cctttcataa ataaaattta
    49921 taattccgat aggattatat caaaaaaagt agttaaggtc tacataaact cttttattca
    49981 tataatttag atatttcagt gtaatataat tatttcttaa ttttttgcca ttcaacgata
    50041 taaccattta atatctctct tatggctttt cctatcttag tataagcttc atcatataga
    50101 tttgctagag atattctaat tgaccattca gggccataga atccatttcc actaagtaaa
    50161 actactgaat agtcattagc taatttataa agaacatcta ctggagatgc agttttactt
    50221 ataaatttaa ataagtcttc tccgtagttt aatttagccc attcttcaat atcaaattga
    50281 gtgtaatatg cagcattgtt tttgttttca ttaattggaa gctctaaagc ttcaaataat
    50341 agtttttgac gtctatggca gatactcata ttgagttttt tgtaggcatc tactttgtca
    50401 atcaatgcaa aagcagagaa aaacgccatt tgtacttgct gtggagtaga aagaccagca
    50461 gtatggttga gagcaacaag tctgctatca gcaacaactc tttccataaa tgaaagacta
    50521 gaagggttaa gactcatatc actgtaacgc ttatctactg atttttttaa ttctccagtt
    50581 aaatcattta ttttcttatc aaaaacattt ttcttatgaa gggcaaatgt accaagtctc
    50641 catcctgtaa ctccaaaata ttttgaataa gaatatactc caacagtgtt gtaaggtagt
    50701 tttgacatta aggatgaaaa atcttctaca aaagttccat atacatcatc tgatattatc
    50761 attaaatctt tattataatt ttcaattaca tctattagat tattacaaga tatttcatcc
    50821 atagctatag aagcaggatt attaggatta acaacgaata aagctttaat agatttgtca
    50881 cgaagtttct ctaattcttt ttttgtatat tgccatgtat gagcaccttt ttcatcaact
    50941 tcattagcat ttatatttac cactttaaag tcgtaacgag gaaggttagg tatttcaaga
    51001 taaggtgtaa atattggagt cattaaggct attgtatctc ctttttttag aagttcattt
    51061 gccattaatg aatcaaatat atagcacata gcagctgtag caccttcaac agcaaaaatt
    51121 tctacatcac catatttacc tgatatatca tatttcattt cttgaactag gtaatcgtgt
    51181 actatttttt ccatatgagg taacattcta tctggaagtg gatagttatc accaataatt
    51241 ccatcagcta gttcatgaac aaattcatct ccatcaaatc caagttcatt tataccaaag
    51301 tttataatat ctctagctaa atatgctcca ggcatatcta tattttcatt tataaattta
    51361 aaaaatcttt ctttaatacc ctttttttga ggcattccag ccaaatgacc taaatcccaa
    51421 ttagaacgag tttcagtaat agcgaaatga ccaaaagtaa aaaaggcttc tctagcagtt
    51481 gaacaagtcc agtttggatt tccacgacct gcatcaagta attctctgtt attttctttt
    51541 gcagtgtatt ttgcaatatc tattaatttg tccttaaatt caaaagggct tatttttcca
    51601 tatatgtttt tgatttcttt ataagtatga tttttcatgt taaattcctc cttatgtaat
    51661 aagtttcaca tttttataat aaaataaaca agttgcaaaa atgattatac tttaattata
    51721 ataggtttat agaaaaagta aagtatgaaa ttaaaataat aact
//
LOCUS       DAMJWO010000017        50738 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.018, whole genome shotgun sequence.
ACCESSION   DAMJWO010000017 DAMJWO010000000
VERSION     DAMJWO010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 50738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50738
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.018"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            95..298
                     /locus_tag="PC366_001069"
     CDS             95..298
                     /locus_tag="PC366_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2576606.1"
                     /translation="MISYAPLWKLLIDRKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKGI"
     gene            462..1616
                     /locus_tag="PC366_001070"
     CDS             462..1616
                     /locus_tag="PC366_001070"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HDF2576607.1"
                     /translation="MKKISILGSTGSIGKQTLDVVREHRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELVNITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFRVEQENIDVVVHPQSIIHSMVQYADSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
     gene            1629..2633
                     /gene="rseP"
                     /locus_tag="PC366_001071"
     CDS             1629..2633
                     /gene="rseP"
                     /locus_tag="PC366_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HDF2576608.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGELKLSITRDGSNKVVNVTPKNNNGKYEIGIQPQREKDFLASIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            2816..3871
                     /gene="ispG"
                     /locus_tag="PC366_001072"
                     /gene_synonym="gcpE"
     CDS             2816..3871
                     /gene="ispG"
                     /locus_tag="PC366_001072"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HDF2576609.1"
                     /translation="MSYERRKTREVSVGTVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSRERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKHGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKKVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            4219..5043
                     /locus_tag="PC366_001073"
     CDS             4219..5043
                     /locus_tag="PC366_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576610.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTNVYLASTVS
                     TVTKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSIWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(5516..6639)
                     /locus_tag="PC366_001074"
                     /pseudo
     CDS             complement(5516..6639)
                     /locus_tag="PC366_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
     gene            6836..7060
                     /locus_tag="PC366_001075"
     CDS             6836..7060
                     /locus_tag="PC366_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576611.1"
                     /translation="MIIKLTKDNFNFRFKQYEGMFFHAEVVEGMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQVEAYIDLNSIK"
     gene            7113..7637
                     /locus_tag="PC366_001076"
     CDS             7113..7637
                     /locus_tag="PC366_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2576612.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     EAMLASLGENDYMFVAETNNNGEKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLTRVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(7742..7888)
                     /locus_tag="PC366_001077"
     CDS             complement(7742..7888)
                     /locus_tag="PC366_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576613.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(8027..8953)
                     /locus_tag="PC366_001078"
     CDS             complement(8027..8953)
                     /locus_tag="PC366_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HDF2576614.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDDHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTSRGFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLVLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            9144..11015
                     /locus_tag="PC366_001079"
     CDS             9144..11015
                     /locus_tag="PC366_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HDF2576615.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKMESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFVRCEKWLKTAADKNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNASCQIKLGNIYEDLNNIEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     SKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYISLANEEYDNCEEIVEGFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDS"
     gene            complement(11107..12042)
                     /locus_tag="PC366_001080"
     CDS             complement(11107..12042)
                     /locus_tag="PC366_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDF2576616.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSNNPNGFWIILLITSIICIVITFFMSRNKLL"
     gene            12562..13074
                     /locus_tag="PC366_001081"
     CDS             12562..13074
                     /locus_tag="PC366_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HDF2576617.1"
                     /translation="MSDFKEILAEEIKNNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QIGFNIEHLNDTPYFKEAKMAIICKKIYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKED"
     gene            complement(13229..14290)
                     /locus_tag="PC366_001082"
     CDS             complement(13229..14290)
                     /locus_tag="PC366_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HDF2576618.1"
                     /translation="MIIKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVI
                     SGVQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEA
                     VKAGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIV
                     VEGPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGRNIPVVAAGGITSS
                     SDVKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAI
                     RNKFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAY
                     KIDKLSTVEDVINELISEL"
     gene            complement(14414..15307)
                     /locus_tag="PC366_001083"
     CDS             complement(14414..15307)
                     /locus_tag="PC366_001083"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HDF2576619.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIESGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPAGIKIKIHSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILGNMIVSVTDNENIHYDIIKIPEELK
                     FCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSRVALLISALLNKNFDLLKVACQDKL
                     HQNYRGTLIENYNDIVEKSEQLNSIGVFLSGAGPTIMSLIKENDDSFVDNMKNYLQKL
                     KSDWEIKELCCDSNGAVLNII"
     gene            complement(15317..16798)
                     /locus_tag="PC366_001084"
     CDS             complement(15317..16798)
                     /locus_tag="PC366_001084"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HDF2576620.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISSDGGLYVPSEFPNVKNELIN
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKKFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVSNSEINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLSDKGVYKISDDMEKNLASFYGEYSNEEEVKSTINNVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     misc_binding    complement(16906..17137)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17939..18847
                     /gene="trxB"
                     /locus_tag="PC366_001085"
     CDS             17939..18847
                     /gene="trxB"
                     /locus_tag="PC366_001085"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDF2576621.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKVKVVKTSSGEHKAKA
                     VILANGVERRKLGCAGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARENIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCTTSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     gene            complement(18937..20760)
                     /gene="typA"
                     /locus_tag="PC366_001086"
     CDS             complement(18937..20760)
                     /gene="typA"
                     /locus_tag="PC366_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HDF2576622.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            20972..21214
                     /locus_tag="PC366_001087"
     CDS             20972..21214
                     /locus_tag="PC366_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576623.1"
                     /translation="MLEVTKIIIKYFASESDTFIKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            21362..21553
                     /locus_tag="PC366_001088"
     CDS             21362..21553
                     /locus_tag="PC366_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HDF2576624.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            21844..24345
                     /locus_tag="PC366_001089"
     CDS             21844..24345
                     /locus_tag="PC366_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HDF2576625.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQSVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYDPSKVKLSQIKAAIEKAGYKPIEEVRNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMTNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKSLFSLSPNMDSLVAIGTLAAFLYSLYTTLQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAIVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINDESILLGNRKLMNDNNIKLGDLEEKSNVLAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNAKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAAAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            24505..25173
                     /locus_tag="PC366_001090"
     CDS             24505..25173
                     /locus_tag="PC366_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2576626.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            25157..26434
                     /locus_tag="PC366_001091"
     CDS             25157..26434
                     /locus_tag="PC366_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HDF2576627.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEIKADQERITKAINNIINNAIKYSPEKSELI
                     IRLYDKNKRISKKTSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVVFTVEFKN"
     gene            26835..27056
                     /locus_tag="PC366_001092"
     CDS             26835..27056
                     /locus_tag="PC366_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576628.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EMKKDEMMERYEQKKFSKELEKQMKNEMK"
     gene            complement(27345..28109)
                     /locus_tag="PC366_001093"
     CDS             complement(27345..28109)
                     /locus_tag="PC366_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDF2576629.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIITEKAPTPDIVDILSEFNVNVL"
     gene            28383..29057
                     /gene="fsa"
                     /locus_tag="PC366_001094"
     CDS             28383..29057
                     /gene="fsa"
                     /locus_tag="PC366_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDF2576630.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKEKKNFKQLIN
                     EIGEIIGEDMPIHAQVLSTKYEEILDEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHGVHSVTVPYDICKSMMNHPLTDWSVDKFIEDWENTFGKG
                     SKTNNI"
     gene            complement(29179..30573)
                     /locus_tag="PC366_001095"
     CDS             complement(29179..30573)
                     /locus_tag="PC366_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HDF2576631.1"
                     /translation="MGIILKPKQFYMTVIVTIILYFSLNYSFNIKFSICLSFLTILIW
                     AVDSVEKTFVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFIFVFKKELHSIKFISNENLEGNKLHFSYSNLKKEFNLLNKEQKHVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     KENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITFPWWKFIGLEI"
     gene            complement(30651..31997)
                     /locus_tag="PC366_001096"
     CDS             complement(30651..31997)
                     /locus_tag="PC366_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2576632.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLKLMNTPESVFAQSKLYLTIIFSGILFSAGYNSVSAILRGLGDS
                     VTPLYFLIIATILNIVLDLTFIVVLRMGVEGVALATIMAQAVSFIISIIYLNKKHEVL
                     KFKIKGIVYDNKIFKDGLRLGLPSGIQQMLFSIGNMTLQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVTVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSKFFGTDGIWMGIPFGWTLGLIVTVIYYKKGYWKTKAIVNHRINE"
     regulatory      32247..32349
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            32443..33819
                     /locus_tag="PC366_001097"
     CDS             32443..33819
                     /locus_tag="PC366_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDF2576633.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEIIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCLGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFM
                     NPEYAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPTNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSVVMIVLAIL
                     FIIKLWLL"
     gene            complement(33933..35078)
                     /locus_tag="PC366_001098"
     CDS             complement(33933..35078)
                     /locus_tag="PC366_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2576634.1"
                     /translation="MNTFEQLKISSTLIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAELSVT
                     SLALIGEVNIQKQIKNIKAVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIVLDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKALAATNPKKAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MEKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     SRGNRSGNTISIITKKELDIIKDLQKEFSIVITPKTLQNGELIDIIK"
     gene            35330..36037
                     /locus_tag="PC366_001099"
     CDS             35330..36037
                     /locus_tag="PC366_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2576635.1"
                     /translation="MLKVINVSKSYKNKKVVSSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFEEGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            36084..37679
                     /locus_tag="PC366_001100"
     CDS             36084..37679
                     /locus_tag="PC366_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2576636.1"
                     /translation="MSNLSILIKTNIINEFKLNALKKADSREKQKIMGMILSVVIITG
                     LLIFYVTSISLSLVDILKQINQMEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDL
                     LTSLPIKESTVLASKILMLVGANYLFSSICMIIPAVVYFFNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFMFIGQISSRIKYKNLILIIGSIILMLLYTLLMTRLNSMSVEMLKN
                     SVSISETIRKIYPPIYYFVDALKTGSVVSFLAFIAISIIPFFMFVTLFAKKFKDINAK
                     MSEGYKSKTYKFKSQKTSRPSKALLKKEFKRYTSSFIYFLNSSAGLLFLIIGTILILL
                     FGADKVGELLKLNIDFNFIKIQLLGVFFFIIVMNCTTYCSISLEGKNLWILKSSPIDE
                     REIFWSKILMNFLLNAPLSILCLILVSIRLGFEIQFIIVSICLIASFSMFVALMGLLS
                     NLLYPNLDWKNEMAVVKRSASMIITMLVSLAYVIILGGIYVLLGISFLNIYIILASIL
                     TFILDFMIWRIISTKGVRIFKNL"
     gene            37782..38864
                     /locus_tag="PC366_001101"
     CDS             37782..38864
                     /locus_tag="PC366_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF2576637.1"
                     /translation="MRKLSKREKDFIQYGFLLFLICITTYLVLTTLDIKLIPKIIRLV
                     NKTYIFLGILTIIVYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLMEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKIFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYVHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSNIIPKELLGYSVLLYSGFVYYFILIVSGLFTFG
                     THYTLNSWKKEDKVNSNLDKVIEKLN"
     gene            39013..39174
                     /locus_tag="PC366_001102"
     CDS             39013..39174
                     /locus_tag="PC366_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HDF2576638.1"
                     /translation="MKQDKQNEKQSEISKIKQSNDNKLEIAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            39515..40783
                     /locus_tag="PC366_001103"
     CDS             39515..40783
                     /locus_tag="PC366_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDF2576639.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            40978..41766
                     /locus_tag="PC366_001104"
     CDS             40978..41766
                     /locus_tag="PC366_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HDF2576640.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSKLNLDYIKEYEDYVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSLRNAKSDYPILNVSVSKHMEQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASREYRKAMSKVLLKRAIMEVI"
     gene            41766..42215
                     /locus_tag="PC366_001105"
     CDS             41766..42215
                     /locus_tag="PC366_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HDF2576641.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKVGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRALDKEITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVLAMKDELENPTDDEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            42219..44483
                     /locus_tag="PC366_001106"
     CDS             42219..44483
                     /locus_tag="PC366_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2576642.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKNALVVKILRSPHAY
                     AKIKDIDTSKAEMVDGVECVLTYKDVPKSRFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAIDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNKTMVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDVVIEETYYTQAQAHAMMETYRAYNYLDHMGRLVVV
                     SSTQIPFHVKRHLSRALEIPASKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKMDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKHLDNGKIRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLDTSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGATKLGVEKDEVE
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDTE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGSMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMEMNK"
     gene            44623..44934
                     /locus_tag="PC366_001107"
     CDS             44623..44934
                     /locus_tag="PC366_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576643.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKVRVFFKEK
                     QNQIEIDFAEEEISKLVENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGSRV
                     H"
     gene            45220..45720
                     /locus_tag="PC366_001108"
     CDS             45220..45720
                     /locus_tag="PC366_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HDF2576644.1"
                     /translation="MRKNSINIALTAAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIISGTLATFISASMIYITRKLGKQNKSTLV
                     IASLWPTVINSIVVGLMLNVFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     VINIKF"
     gene            45777..46763
                     /locus_tag="PC366_001109"
     CDS             45777..46763
                     /locus_tag="PC366_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF2576645.1"
                     /translation="MSKVKRLTDVWIYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMIILFALKSLQIYNYKLMEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANDTNDGDFKSSNVTEFFRASSESLILNIKY
                     KCGNQILEKNVCPIGIYLNKGAWFSPAYDCKSDKIILVHIDNIIDIKRTGESKKIHIN
                     LEEWLHEVYNNLYGNSSTTKKFGEIIYLNVLLTKEGVSKIKDSSWNLDMELNEDGSGI
                     ISTFIKVEDIDCYASILFFIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            46813..47535
                     /locus_tag="PC366_001110"
     CDS             46813..47535
                     /locus_tag="PC366_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HDF2576646.1"
                     /translation="MENFNKNAKIIGIGVEGINIINEVEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIRDIIKAVSYMSNERRVLSIGMDCSEKENKEDLE
                     LGREFKINNDSIFKFVDLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFEEFED
                     TKSYSEIADILFDRMEYIGEEFISKKGIVFVEGSPEFSIMELNDLISNIQSKVEESYE
                     VIFSLYIKENLNGNIRVGLLYN"
     gene            47564..49498
                     /locus_tag="PC366_001111"
     CDS             47564..49498
                     /locus_tag="PC366_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2576647.1"
                     /translation="MSENIRGTEYWLMEEFFYQETDTPQIFIEESIIALGFDIKINLK
                     KVFSMGKKSEKYINENCNDKDFIKKFMSIKKGDYFLYKAYQNIEEKVKCNVSIGIVEE
                     DFENGYELSHILGHTLPVKWMHNFDTVSNCKVYTSEFYKLNNNDISSYLEIIKSQDKK
                     LLRKRIEESENNKWYLKNYYYKNVDKCVDDEELFIQPINLEQLESLKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFDKEKVSALDGGYFFPVRWIEYGKENIDGNAWV
                     IFENNSIVEKYVKRFTNKMPLNTILYGPPGTGKTYNTKQMVYNLVSETSLRNKYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKPEDGILKDISIEACYNALKFEKKM
                     SFELEKDSLTLETIKDRKKKLVLENIEYSESFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFSLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPDYDLLSIVDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEKLIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            49491..>50738
                     /locus_tag="PC366_001112"
     CDS             49491..>50738
                     /locus_tag="PC366_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HDF2576648.1"
                     /translation="MSKNIYVKETYEWIRVGNGENELTEIEYEKLLKYLENNNDVLKS
                     NIIDIKYKKIRFINYVGIICFENVILEILPKLSLSDNLVKDREILLQMLSICNKIPIT
                     MNEKIRLSLKNYNLLNFFVMYFIESMQTQMKKGIYFEYINKIENLNVMRGKILLSTYA
                     KEKGISPMKIRCEYDECSENNFLNQVLKKACISILCRINDNSIQGKIKKILSYFQNVD
                     LIYIDRKKLLGYKFYKNNDRFKDCYLLARLLLLNLSMDNSQNNQEAFSILFEINTLYE
                     EYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLKNEYEIIID
                     TKWKAIEVDSNVFYRSSDIYQMYAYITAYENAKRCILLYPCIQKDKNYSSWKLSESFK
                     GKFIEAKTVRLDDIKNTKNDLKKI"
BASE COUNT        19611 a         5688 c         8159 g        17280 t
ORIGIN      
        1 gaaatctatt tagataaata attatttatc taaatagatg aaaattttcc aaaatagata
       61 aaatgtgata gaatatattt tgcgaggtga taacatgatt tcatacgctc cattatggaa
      121 attgttaatt gacagaaaaa taaagaaaat ggaatttgta aatatatcag gtataagtat
      181 ttctgtttta ggcagactag gaaatgataa atctgtttct atggatacaa tggagaagat
      241 atgtttagca ctagactgta aaatagaaga tgttgtggaa ataaaaaagg gcatttaata
      301 atactagaat attttataat attccacaag atacaaaaaa taatagatta attttaatct
      361 gtggaataat atatgaaatt tctatgaata gtaaaaataa ttgttttagt agtgttataa
      421 tgttttgaca gggtatattt attattagaa aggattatta tatgaaaaag atatcaattt
      481 taggttctac aggctctata ggtaaacaaa ctttggatgt ggttagagaa catagagata
      541 agtttgagat agttgcaata tcagctaaca gtaatattga attattgcta gaacaaatag
      601 tagagtttaa acctaaatat gtaacagttt ttgaggaaaa taaggcattg aaattaaaag
      661 aaatgttgcc taaaaatata gaaatagaag ttttagcagg aatggaagga ttaaaaataa
      721 tatcatcact tgatgaagtg gatgtccttt taactgctgt agtaggtatg ataggattag
      781 tcccaactct ttgtgctata aagaagggaa tagacatagc attagcgaat aaagaaacgt
      841 tggtaactgc tggtgaactt gtaatgaaag aagcagaaaa atacaatgta aatattcttc
      901 ctgttgatag tgaacatagt gctatatttc aatgtctaaa tggagaaaat aaaaaaaata
      961 tagaaaagat aatacttaca gcatctggtg gtccatttag aggaaagaaa aagggagaac
     1021 ttgtaaatat aactaaaaat gaagctttga agcatccaaa ttggagtatg ggaagaaaaa
     1081 taagtattga ttcttcaacg cttatgaata aaggacttga agtgatagaa gctagatggt
     1141 tgtttagggt agaacaagaa aatatagatg tagtagttca cccacaaagc ataattcatt
     1201 caatggtgca gtatgcagat agctcaataa ttgctcaatt agggtgtcca gatatgagac
     1261 taccaataca gtatgctctt acatatccag atagaatgga aagtagcttt gaaagaatga
     1321 atttttcaaa atttagtact ttaacttttg aagaaccaga tttagaaact tttccatgtt
     1381 taaaattggc ctatgagtgt ttaaaaatgg gaggaactta ttcttctgtt ttaaattcag
     1441 caaatgaagt tttagtaagt gaatttttag aggataaaat tggtttttat gacataccat
     1501 attacataga gaagacttta gaagttcata gtagcataag cgaaccaaca ttagaagaaa
     1561 tcttagaaac agatagatgg agtagagctt atgttgcaaa tctgataaaa aaataggaag
     1621 gtgaatttat gactataata gccgcattaa tactatttag tataattgta ttaatacatg
     1681 agttaggaca ttttatattt gcaaaaagaa gtggtatcaa agtaaatgag ttttctatag
     1741 gtatggggcc taagatatat agtgtaaaaa aagatacaga gtattctata agagcacttc
     1801 caattggtgg atatgtcagc atggaaggtg aagatgaaga acaaataagt ccaaattctt
     1861 ttggaaacaa gtctatatta caaagattta gtactattgt agcaggacca atattcaata
     1921 taatattagc agcaatactt ttagttccag tatttttgta tataggttct ccaacgacta
     1981 aattaggaaa gataatgcca gatactcctg cacaggctgt agggcttcaa gtaggagata
     2041 agataaataa aattaatggt aattctgtta agacttggga tgaagttgca aatataataa
     2101 acacttcttc tggtggagaa ttaaaactta gtataactag agatggaagt aataaagttg
     2161 taaatgtaac acctaaaaat aacaatggaa agtatgaaat agggattcaa ccacaaagag
     2221 aaaaagactt tttggcgtca atagtaaatg catgtaaaac tactgtagat atgacaaaac
     2281 agatgttaac atttctaggt caaatgatta caggacgtgt accaggaggg attggcaatg
     2341 ctgtagcagg accagtaggt gttattggta tggtatcaga tgctgctcgt acaggcatca
     2401 taaatgtagt gtatttagca gctgtcataa gcttaaattt aggtatagta aatctattac
     2461 caataccagc acttgatgga tggagaatac ttatgctatt actagaagct gttagaggtg
     2521 gtaaaaaact cgacccaaac aaagaaggca tgataaatgt tgttggtttt ggagctttaa
     2581 tgttatttat gctttttatc acatataaag atatattaag attatttcaa tgatttagtt
     2641 ttttagagat tttaagaaaa taggctatgt agttttaaat aagaataaat taatttttat
     2701 gtatgaaatt tattcttatt taactagata gctttttaat ttataatata catgtaggtt
     2761 ataatatttt actatttaaa gagattcaat ataaaataat atatagaggt ggaatatgag
     2821 ttacgagaga agaaagacga gagaagtaag tgtaggaact gtaaaaatag gaggagaaaa
     2881 tcctataagt atacaatcta tgacaaatac tgatacaaga gatgcagatg ctacaatagc
     2941 tcaaataaag agactagagg aagctggttg tgatatagtt agagttgctg ttcctgatat
     3001 taaagctgct aagaatatag caaagataaa gtctagtgta aatataccaa ttattgcaga
     3061 tatacatttc gattataagc tagcccttga agctatagaa caaggtgtgg atggaataag
     3121 aataaatcct ggtaatattg gaagtagaga gagagttaag atggtagttg agaaatgtaa
     3181 ggaaagaaat ttaaaaatta gaattggagt caatggaggt tctttagaga aagaactttt
     3241 aaaaaagcat ggctctgcaa ctgctgaagc attagttgaa agtgcaatgg gacatattaa
     3301 gattcttgaa gacttagatt ttcataatat agttatatct ctaaaatcat ccgatattta
     3361 taaaactgtt gatgcatatg aattaatatc aaaaaaagtt gattatcctc ttcatattgg
     3421 aattacagaa tctggaagtg ttcacaaagg aacaataaag tcttctatag gggtaggagc
     3481 acttcttctt aaaggaattg gagatactgt tagaatatct ttaacaggcg accctgttga
     3541 agaggttatt gttggtaaac agattttaag aagtttggga cttttaaatg ataagattaa
     3601 agttatatca tgccctacat gtggtagatg taatatagac ttaattagtg ttgtaaatga
     3661 ggttgaagaa aagattggta gtatggaaaa aaatatcact gttgcaatta tgggctgtgc
     3721 tgtaaatgga cctggtgaag ccagagaagc agatataggt attgctgggg gtaaaggtga
     3781 aggtctttta tttaaaaagg gtgaaatagt tagaatgatt gatggtaaca aattagttga
     3841 tgagttgcta gaagagattg aaaaattata gtatacaatt catatatata ttaattgact
     3901 agatttttaa atacttttgt aataagtttt tatttacagt atttaattat ctagtcattt
     3961 tttattttat aaacttcatt aaatgtaaga aacttatatt ctaatttgac tatatatgta
     4021 tgagttaaat catattgtaa atttataaaa ttaaaaaaag atttaatata gtgaaaattt
     4081 ccatcaatag tattgaaact tgatagtaac tatgatagga tatagttact agaacagttg
     4141 gtaaattatg ttaacataga ttttaatgtt ttggtaaatt gttttattat aagttaatag
     4201 aaaaagaggt gaagaactgt gagatataaa aaaatatcta gcttacctat tttagttgtt
     4261 gctttgctga ttactggaac gacaacaaca ttttctctta gtacgaccaa ttcagaaaaa
     4321 acaaatgtat acttagcaag tacggtaagt actgtcacaa agaaagtatc cgatattcaa
     4381 agtagtaaag gtcttgttta taatgagaat attccattat ttataaataa tagcaaaata
     4441 cagtatgatg atactccata tcattggcct agcaatgtta taagcttaac aaatagcagt
     4501 gaaaaggcaa ttatggatta tgagattaca tgcttagcat atgataaaaa tggaaaacca
     4561 cttgagctat attgggatgc tcaaaatgtg gcagcagatg gcgaagtagg aagtgttgga
     4621 tttagcccag ctggtgtaga ctatggtatt gttacaggca tatctcctgt gtctccaaaa
     4681 tcatattcac atacttatag aaaaatgcaa caatcaccac cacaggatat aataagtatg
     4741 tttgaaaaac aacaaggcaa ggcatgggta gaaaattggt tgaaagaatg gaaacaaatg
     4801 gagaaagaat atgcaaagca aaatgcaata gcaccaggta agaatcaaaa tgatgccttt
     4861 ctattgtttg ataaatggaa acaatcaact ggagagcatg gtgtaaagta cattatatct
     4921 tgtgtaaaac aagtaacatt taatgatggt agtatatgga aaaattcagc atatgagaat
     4981 tggttgaaaa gttttcaagg gaaggaagtt tcaaatagtg tattagaaaa ttactataag
     5041 taatgtttaa tgatagcaaa atgagtacga atttaattaa tgttaattta attaaataag
     5101 gactattttg tttaaaaata tcagtgttac aaggaaattt ttattgtgac aaaatggtat
     5161 atattcaaaa taaaaaagca tgtgtcaagt tttgatacat gcttttttat tttgaatata
     5221 tgttttctat aaatttatga ttttttagtt atgtaatttt atatgtgaat ttttagattt
     5281 ttatatagat agtgaaataa tgtggaagtt ttatgtttta aaaattttag ttaaaacatt
     5341 tattaaaaaa gataatagaa atgttttaac taaaatagtt agaattgaaa tgttatacag
     5401 atagtataag tactatcaaa ttatataaga ttgcttgaag ttaaataatt tatttaaata
     5461 gaaaacagct gatttaatat cagctgtata tgaataaaat tttgaattgt agtgtttagt
     5521 tatatggata taattcataa taagttagca ataaatcaac cattttacca taactctgag
     5581 taccttcagt aacgccatta gcttttaagt aagaattgtt aaactcatta gaaatttcat
     5641 taattttacc ttcatatttt tgccaaaatt cactttcatt ttttaaatct ctacggacag
     5701 aatctgaaat gccagcagaa atatcaacat atgcattata atcaacctta cttaaagcag
     5761 aagcagtata atttaaagct aaaatatatc cagaatagtt aaaatcaata tgggggtgtt
     5821 ttatagaagt aagatacgct ataaaattag cctcatcttc actagcaaat cccctttgat
     5881 gtgctatttc atgttcaact gtacaaggaa tatataagtc aggtattgct atatttacat
     5941 ttgcctcacc tgtaaaagga aagtatatac cagttattcc tgtatagcac attagatttg
     6001 atgaaataat atacttaggc ttagaataac taccactaac actaggtaat atatccaaga
     6061 tattatcgta tcctagttga gctctattta tgacaccatt ataatctgta ttagatttta
     6121 caataccatt tttatcttgt aatgtgagtt ttctagtttc atttgcttta attacaagga
     6181 atttatataa tttagtaagc tctttaacac tatattgttt tgattggata gaggtattgt
     6241 tttttaaatt atagttattt ataagtgtgg tttctagtgg aatcctatta tagtttattc
     6301 cccaaagcac tacaaaaaga aagtagacta ttgatacaat ggataatata tttaaaatgg
     6361 aattttttaa aaatatgttt aatttttttt cttattaaaa attgtagata aagtacaaca
     6421 taaaaataag aagatagata taactattat gtacattgta atctcataga gagaaaatgg
     6481 gaaaattcca gaaactttac tcaatatttg tacaattatt ttatctatga attgggagta
     6541 atatttttca acaatatttg gaactttgct ggctataaaa tttaaaagta aagcaatagg
     6601 aaagagaatt aaagaaaaat attttgtttt tttgctcata tttcacctca catacattag
     6661 tttatataaa catattatat atcaattgaa gaaagattgt aaaataagta taaatatatc
     6721 tatttataac tttatactaa ataaatgata agttataata tattaatatg aataagcagt
     6781 atatatacaa ctaataataa gaaaaatatc aattatataa ggagtagata aaaatatgat
     6841 aataaaactt actaaagaca attttaattt tagatttaaa caatatgaag gtatgttttt
     6901 tcatgctgaa gtagttgaag gtatggaatc cattagatat aaaataacta aggataaaga
     6961 aggtacagaa ttaaaagaat ttggaagtac acatataaaa gataatatga tatatgtacc
     7021 tcaggtagaa gcatacatag atttgaacag tataaaataa agatgtaaaa ttttaattaa
     7081 aaataaagat tatgtttgag ggggaatcca atatgagtaa gcctatagat ataacaataa
     7141 gacctataag aagagaagat gcacaagctt ttaatgaaat tagaagaaca tacagtgtta
     7201 tgagaaatac tttggcatta atgagtgaca gagtcgataa aactgaagct atgttagctt
     7261 ctttgggaga aaatgattat atgtttgtag ctgaaactaa taataatgga gaaaaagatg
     7321 taataggttt tgctgggtta catgtaaatt cttctccacg attgagacat agtgcagaaa
     7381 taggaataag tgttgcagag aattatcagg gaagaggagt aggtaagaag cttatggaac
     7441 aacttttaga tatagcagat aattggatta tgttaactag agtaggatta gaagtaattg
     7501 tagataatga aaagggatta aatttatata aaaaactagg ttttgaaata gagggaacta
     7561 aaaaatatgc tgtaatcaga gatggaaaat ttgaagatgt ttatattatg ggaagatata
     7621 ataaaaattt aatttaaaga agctaataga gaagtaaaat agagtgtctt taataaaaaa
     7681 tttacattaa aaataatcta ttttacttct ctattgtatt aaaaaactta tttttaaatg
     7741 tttacaaaaa cattctatat acaaataaaa ttattagcaa tatcaacgct attttaaaag
     7801 ctaaactagc aacagtttta atgattttta cagaaacacc tatagcaact atagcaaata
     7861 ctattttaaa gagtaaatcc atatccatat ttaagcctcc tattctataa tacatataga
     7921 tattattgac aaatatctag gaaaaaattc catcaatata ctacaataaa atgtttatat
     7981 ttgtaattta ttgaatatgt tattatataa tacataaaaa aataaatcaa gataagagta
     8041 aaatacttat aaaaggtata gatataactg aaaatagtgt tgtaaaaaac acacattgtg
     8101 aagctagtgt tatattggag tcatattgat tagccattat agcagtattt gcagcagcag
     8161 gcattgaaga aattactact ggtatagcta aaatcatctt atcatttatc catcctttta
     8221 gaataaaata cacaatcaca ggaagtacca ataatcttat aaaagtgact atatataatt
     8281 ttttgttgac aaaacaatcg agagctgaag aattagcaag taagcttcca atgataatca
     8341 tggatattgg tgtagttata cttcccaaca tctcaagtgg ctcgtttata aattggggta
     8401 acctaagtcc tgttacaaat aaaaaaagtc caataacaat agctattgta gcagggctta
     8461 taagtgattt tattgaaaaa cctctacttg tactgccttt agataaaaga taaattccta
     8521 aagtgaaaga aaataagtta aaaggcaaat tgaatattgc agtatagaat attgcttcat
     8581 gacctaaaac tgcttcaatt acaggataac ccataaaagc aacatttgaa aaaacaacta
     8641 tatactgata tattcccaaa tcttttttat cattacattt taaaatgtat ttcaataaaa
     8701 atgcaattat aattgaaact atatacataa tcaaagatgt aaataataac aatagtattt
     8761 tttgtatcat tttactatca aagttaattt gcatggagct aattatcatt gatggtaaaa
     8821 aaactgtcat tgtcaaagtt gaaagcttag atgtgcagtg gtcatctaat aagttgaatt
     8881 ttctgacaaa atatccaact aaaataatta taaataaaac tgcaacttgg ataaaaatat
     8941 tgctgaaatt cataaaatgt ccccccctat atatacatta tataccaatt acataataaa
     9001 atctaatgat tataaaattt aaaatttaat gttacaatat agtgacaaaa ggtaaaaatt
     9061 caatattata gcattaatta tagattataa tgtataataa tgtttgagag aatatatttt
     9121 ataaaatggg taggtagcga ataatgaaaa atacaaaatt ttctataaaa aaaataaaaa
     9181 atatatctaa tgacccgaaa gtcgtacata ctaagggtgc cctccttgaa aagatgggta
     9241 agatggaaag cgcaatagag ttgtataaga gtgctgcatt ggataattac gtaaaatctc
     9301 aatatacttt aggaaatata tatgaaagta aaaaacaatt taaagaagca gaaaagtggt
     9361 attcaatggc atataaaagt ggaagtgaag atgctgcttt tgatttaggt aatatgtact
     9421 ataagttaga tggctatgaa tatgctatat attggtatga aaagatagca aatttaggtt
     9481 atttacaagc acaaaataat ttaggtgtat gccattttaa aatgaaagat tttgtaaggt
     9541 gtgaaaaatg gttaaaaaca gcagcagaca agaatttagg taaagcttgt tttaatttag
     9601 gggtattata tacttttttg gagaaagatg atgaagcata tgaatactat aaaaaaggtt
     9661 ctgtgctttt agatgatgat gcaaaatata atttagcaat attaaatgga aaaaagaaag
     9721 ataataaatc aacagtaagt ttatataaac agttgtacaa gtcaggtcat atgaaaggtt
     9781 gctttaactt gggtatgatt atggaaataa atgataattt agaagatgca gagaagtatt
     9841 ataaaaagag tgctgataga gatgatgtga agtctgagta taggcttgca tatgtatatg
     9901 atagaaaaga agagctggga gatgcaattt attattatga gaaagcaata gaaaaaaatc
     9961 atacactttc taagtataga cttgctaatt tatataatag agaaaatgag atagagaagg
    10021 caaaaactta ttataaaatg gctgctgaag atgatataac agaagcaaaa aataatctgg
    10081 caggtatata ttttgaagaa aaagattatg aaaatgctat taaatattat gaggatgcta
    10141 tagctgttgg atgcaaaagt tcccttgaaa atcttgggga tttatattat cagaatcaag
    10201 atatagaaaa agcgatttcg tattattcga ggattccaaa taatgcatct tgtcaaatca
    10261 aattaggaaa tatctatgaa gatttaaata atattgaaga agccataagt tggtataaga
    10321 aagcatctga aaatggagat acgaggtcta gttatagatt ggggtgtata tatgagagct
    10381 taggaaatac aaaaaatgct agaaagtatt ttgaaatggc aagtagcaaa aatcatatga
    10441 atgctcgtat acatctaggt agaatttatt ttagagaagg taaattggaa gagtctaaaa
    10501 tgatgtttga tacacctgcc aatgaaaata atgtgtacgc tcaacatatg gtaggattaa
    10561 tttatgatat gttctataaa gattatgtaa attctaaatt ttggtatgaa aaggctagag
    10621 cacaaggttg tgttgaatca atatataatt taggccaaat ttatttaaaa ttaaatgatg
    10681 acgcagaagc tgagaaatat tataaagaag gtattaaata tggaagtaag aagtgtgagt
    10741 atatgcttgc aggtctttat tataaaaaga gcctagatat gtacatttct ttagcaaatg
    10801 aagagtacga taattgtgaa gagatagtag aaggctttcc caatttaaat atagactttg
    10861 atgaagtatt aattcctcca tttaagttgc aagaagaggt aatagatgaa gaagagtatg
    10921 taccaattta tatactaaat ataaaagaaa gtttagattc aatgctagaa gggcttgaaa
    10981 ctgaaatgat tatagatgaa gaacatgata gttaaaaagt attataagat tatatagatt
    11041 taaatatata aaagccatta ggataaatgt aaatcaatta attctaatgg cttttttatt
    11101 aatattttat aatagcttat ttcttgacat gaaaaatgta atcactatac atattataga
    11161 ggtaataaga agtattatcc aaaatccgtt tgggttatta gaaaatggca tgttgatgac
    11221 attcatacca aagaatcctg atattattgt aggtattgag aaaattagtg taactactgt
    11281 taaaatttgc ataacattat tctgattatt acttataatt gcactgaaag catccataat
    11341 tctactcaat atatctccat atattttagc catatcaaga gcctgtctat tttcaactat
    11401 aacatcttct aataggtctt catcatctgg atacttcttt ataccagcag ttctaaccat
    11461 tttgtttaaa acaagttcat tagattttag tgaggtagag aagtatacca aagatttttc
    11521 taattccaat aattgaacca attctttgtt tttcattgat ttgtaaattt ctcgctctat
    11581 tatgattgtc attttattta tttttcttaa gtaatgcaag taataagctg catttttgtg
    11641 aagaatttga agcaaaaagc gagtcttttt aaacgtaaaa aaatctttaa tatgaccaac
    11701 tataaagtca tttaaaatct tagtctgtgc atcacaaact gttacaatag cttcttcagt
    11761 tagtataata cctaagggta ttgtagtata atgagaagaa ttagagtcac tttcgtctac
    11821 tggtatatct ataagtataa gagtatgatt gtcttcaaca tctattcttg agcgttcttc
    11881 ttcatctagt gcagattcta tgctttctac atctatattt aataaattag aaatttcgtt
    11941 gatttcacta tgattaggtt caacaagatt tatccaacag ccatcttcaa aaaaactaag
    12001 tttctctaat tttgaatcta tagttttgta atatcttatc atggcaacac atcctttatt
    12061 cagttttata taaatctcat catttaatag tatctattaa ttaactaatt tatataactg
    12121 aatatatgta ttagttttga ttttagatat tattaagtga tgaaaatgta aaaaattctc
    12181 tccgcaacgg actagtatcc attgcccatc actctcctta tttattattt tatatatagc
    12241 tatttatgaa atgcgtattt taagcactct ttaatataat accttttcca ggtatataaa
    12301 tcaagttttg atttgattaa ataatatttt taccataatt tacacataaa gtatataagt
    12361 tatatttaat ttgagtaaag aatatatata ttctgagtga aattattaaa tatattaaaa
    12421 aataagagtg tatatatata tttacttatt tgcaataata tatttaaaaa agtattttat
    12481 tttcaaaact agacttcatt tataatttat cacgaaaata aaaggaatat aaatataaga
    12541 gaatgagagg ttattagaga tatgagtgat tttaaagaaa ttttggcaga agagattaaa
    12601 aataatccat ttggattgat aggtaaagat tggacactta taacagcaga aaatgaaggt
    12661 aaagtgaata caatgactgc tagctgggga ggacttggag ttatgtgggg aaaagatgtt
    12721 gcttttgtag taataagacc acagcgttat actaaggaat ttatagataa tacagataaa
    12781 ttttctctta cattttttga tgaagatttt cgtaaagagc tttcatattg tggaaaggta
    12841 tctggtagag aagaggataa gatatcacag attggattta atatagaaca cttaaatgat
    12901 acaccttatt ttaaggaagc taaaatggct attatatgca aaaaaattta tagtcagaaa
    12961 cttgaacccc aatgttttat tgctgaaggt atagatggaa gatggtatcc acaaaaagat
    13021 tatcatactt tatatatagc tgaaataacc aatgtacttg taaaagaaga ttagttataa
    13081 gggttaatac tatctctaat taaattaaaa tttcaataaa aggaaattga cacaaaaaag
    13141 ctaaggacat aaatatgttt ataaagatta ataaataacg tattaaaact ccttagcttg
    13201 ataaaatttt aatttagttt tctttaaatt ataattcaga aatcaattca ttgataacat
    13261 cttcaacagt acttaattta tcaattttat aggcatcatt tccacaaaat aaaagtgaat
    13321 tttcaacatc tcctttaact gcattgatta gagcttgaga aatacagtaa ggagtttctt
    13381 ttggattaca aggaatcaaa caattatagc acttctttat ttctggacga tttattttaa
    13441 cttcttctat aaatttgttt cttatggcgc gtccaggaag acctacagga cttttaacta
    13501 tatgaacatc ttcttcacta gcatttatgt atgccatttt aaagttctca tgggcatcac
    13561 attcgtaagt agcaacaaat cttgtaccaa cttgtacacc acttgcaccc atatctatat
    13621 attttttaac atcactacta gaagttatac caccagcagc aactactggt atgtttctac
    13681 caaatttttc tccataagta tttgcaacct ttaaaatttc aacaaattcc ttatcatagt
    13741 ctatagaatc tatgttatca agttcctcgt tagagtatcc aaggtgacca ccagcttttg
    13801 gaccttcaac aactattaag tcagcagtag ttttctcttt tctatcccac atttttaaaa
    13861 ttacattagc agcttttgca gttgaaacta tgggtgctat ttttacatta cttcccttta
    13921 ctaatgatgg tagcttatta ggtaatccag ctccagatat tataaggtct acaccagctt
    13981 taacagcttc ctttacgtat gtttcatatt ctttcatagc taccataaaa ttaataccaa
    14041 taataccacc atttgagatt tctttggcct tagaaatatg tttttttata gctcttaaat
    14101 ttgcatttat agtattagtt tcaaaatctt cctcatcata tccaatttga actccagaaa
    14161 ttacaccaac accaccaagc ttagcaactg caccagctag tgatgaccta gatataccaa
    14221 cgcccattcc accttgaatt ataggaactt ttgcaactaa atctctaatt attaactctt
    14281 ttatgataat ccctcctcaa tgtaaacatg tttaaagaac tagattataa tacttaatat
    14341 tattacctag tcctaattat tatactacaa attataataa aagagtagtt atattttgta
    14401 tagaagacga taattatatt atatttaaaa cagctccatt agaatcgcaa cataactctt
    14461 ttatttccca atcagatttt agtttttgta ggtaattttt catattatcc acaaaactat
    14521 catcattttc ttttattaaa gacattatag taggtccagc tccacttaaa aatactccaa
    14581 tactatttaa ttgttcagat ttttcaacaa tatcattgta gttctcaatt agagttcctc
    14641 tataattttg atgcaatttg tcttgacaag ctactttaag taggtcaaag tttttgttta
    14701 gtaaggcaga tattagtaaa gcaactctac taacattgaa taccccatca gaatatggta
    14761 tttcctttgg taaaacacct ctagcttttt ctgttgataa cttaaaatta ggtatcattg
    14821 cacaaaattt aagttcttca ggaattttta taatatcata atgtatattc tcattatcag
    14881 taacagatac gatcatattt cctaaaatag caggagcaac attatctggg tgaccttcta
    14941 tttctgaagc tatatttaat aattgatttt tatctaaatt agcacctgat agagcatttg
    15001 cagctataac tccagctact atacaagagg cactactgcc aagacctcta catataggta
    15061 cttcactgtg gatttttatt ttgataccag caggtatttt ttctggttta actctatcaa
    15121 aaaagtactt catagatgta taaactaagt tattttcgtt tttgtaagca tcttcacaac
    15181 cttctatttc aagaccactt tcaatttctt caacataaaa tttattgtat atatttaacg
    15241 caattccaag acaatcaaat cctggaccta tattagcact tgttgcagga actataatct
    15301 ctaacataat aatcacctat acctttaaga atttttttat agctagtttt aattcatctt
    15361 tttcataaat atctttatgt agtatttctg catttttaag atttttaata ggttttggaa
    15421 tatctatttt agaaatactt gataatctat caattatagc aaagtcatca aggtctttaa
    15481 aatcacaatc tatagacttt agaacatctt cagaaaactt gaatggactt gcagtactta
    15541 caataacagt ttttgtgtta tcagaagttt cttttttata tttttcataa caattgtatg
    15601 caacagcagt atgagtatct atcaaataat tataattttt aaacacattg tttatcgtgc
    15661 ttttaacttc ttcttcattt gaatattctc catagaatga ggctaaattt ttttccatat
    15721 catcacttat tttgtagact cctttatcac taaggtctga taacagctta tttacaatat
    15781 cagtatttct atttgatatt tcaaacagta atcgttctaa attacttgaa attaatatat
    15841 ccatagaagg agaagtagtt aatttcaatg ttctattttt atcatataca ccagttttaa
    15901 agaaatcata aagaacatta ttatcatttg atgcacatat caatttgttt attggaagac
    15961 ccatttgttt ggcataatat ccagctagaa tattaccaaa attaccagtt gggacaacaa
    16021 aatttatttt atcatttaaa tttatctcac tattgctaac taatttcata tatgaataaa
    16081 aatagtatgc aacttgtgga agaagtcttc ctatattaat tgaatttgca gaagataata
    16141 tataattatt atccaatagt ttttgattaa attttttatc agaaaaaatc ttctttacac
    16201 ctgattgtgc atcatcaaaa tttcctttta taccaactac atatgtattt tttccagttt
    16261 gagttttcat ttgaagtttt tgtactgggc ttacaccatc ttctgggaag aatacaatta
    16321 tctttatttt atctatatct ttaaatccct caagtgcagc tttgcctgta tctccagatg
    16381 tagcagtaag aatcacaaca tctttctcta aattatcttt ctttatagat gttttaagaa
    16441 gatgaggcat tatagtaagt gccatatctt taaatgctaa agttggaccg tgatatagtt
    16501 ctaagaaata agtatcattt actttattta atggagctat actactacaa tcaaactttt
    16561 catcatatgc attttctata caatttttaa tttcatcttc agtaaaatca cataaaaatt
    16621 tactaagtac aaaaaatgct atctgagaat acgttaaatt tactaaattt ataagttcat
    16681 tttttacatt gggaaattca cttggaacat aaagaccacc atcacttgat attcctttta
    16741 ttattgcttg tgatgcagtt actttttctt cggtgcctct cgtacttgaa taatacattt
    16801 tttataatcc tccatatatt ttaaattttt aattagctaa ttaaattaga tacagaatat
    16861 tttaaaaacc gaatttaggt aataaaaaaa gaccctcatc cctaaaaaag ggacgagaat
    16921 ctgtttcccg cggttccacc caaattgatt ttaaaaaatc cacttgatac tttaacgcaa
    16981 gtaataaaaa cgtctattcc tactaaaatc attaagataa cttcggatag aagctcctag
    17041 gtagttttca atccttctaa ttagggaaac atttcagcta gtagtttcct tctctggtaa
    17101 tcgattcaga tttactcttc ctaatcaatg cctttcaata ttcttaatat tattaattat
    17161 tctagtttat aaaacagaca aagtcaagta ttaatataaa aatttggaaa aaatattttt
    17221 taaattgtaa aaaaattgta atcaaattga gtattagaaa aatatttttt taactttttt
    17281 aaaagtttaa aaacctagat tttcatagtg atgaagctgt ttttaatgaa agtaatcaaa
    17341 agataactat taaatatctg taatattaca attttatact acactatatt acaaaaaaag
    17401 tttacaaaac tttaatttga aaaatgtaat tatatggtat atcatataaa tataagtaaa
    17461 tagtgctaat atttaaacta ttaatcataa ttggttcaac aaaagtatat agttaataat
    17521 gtttaatttg aagaaattgt tagtgtgaaa ttacatatat attcaaatta aattcataaa
    17581 tatttcacat aataatagta tactgtaaac aaaaggaggt attaaatatg ggaatagtac
    17641 ttataacagc agcattagtt ttggttatgt atggactttc aattctatca tatatatcag
    17701 aaagcaatat attagaagac actgtaaatg ataaccaata aggttttgaa ttatataaat
    17761 aagtgagaac tgtaaataaa agttaatttt tatttgcagt ttttttatat atatgtaaaa
    17821 taaagttaat taataaaaaa taatgttttg tttgtagtat atatggataa taatagtaaa
    17881 gtataagaat gatgagaata atatataaga aataataata taaagagagg taaacattat
    17941 ggtagatatc attgtaattg gtgctggacc agcaggttta acttcagcaa tttatgctat
    18001 gagagcaggg ttaagcgtta cagtatttga aaaaaatatt tatggaggtc aagttgcaag
    18061 tacctctgag gtagaaaatt atccagcagt tcaaaagatt tctggggtag aattttctaa
    18121 taatatatac aatcaagcag ttgctcaagg tgttgatatt cagtttgatg aggttgaaga
    18181 gataaattta gagggaaaag taaaggttgt aaaaacttct tcaggtgaac ataaagcaaa
    18241 ggctgttatt cttgcaaatg gagttgaaag acgtaaatta ggttgtgcag gggaacaaga
    18301 atttacaggt agaggagtat cttactgtgc aacatgtgat ggagcctttt ttaaagataa
    18361 agaagttgct atagtaggtg gaggaaatac tgcactagaa gatgctttat ttttagctaa
    18421 taattgtaca aaagtgtatt taattcacag aagagatagt tttagaggtg aagaagtgtt
    18481 ggagaaatct gtgaaagcaa gagagaatat tgagatactt tacagtcatg gtgtagaaaa
    18541 aatagaagga gaaaagactg tatcgaaaat agaagtaaaa aacttaaaga ctgaagaaaa
    18601 aagaactata gatgttagtg gtatttttat tgctataggt cttaaaccta ataataaaat
    18661 gtttgaaaat gttcttgatt tggatgaagg tggatatata atttcagatg agtcttgtac
    18721 aacatcagta gaaggtgtat atgtagcagg agatagtaga actaagtttt tacgtcaaat
    18781 aataacagca gcatcagatg gagctattgc agccgttcaa gcagctaatt atataaatgt
    18841 tgaataatat aaatttcaaa taaaaatagc catataaact gaaataattt ttcagtacta
    18901 tatggctatt ttgttaatta gaggtaaatg tacgttttat ttaccttgtc tagatttgtt
    18961 atatcttaat ctatcatgtt catttaagaa tctttttcta agtcttatag aatcaggtgt
    19021 aatttcaact aattcatcat cttctataaa ctctagtgct tcttcaagag taaatattct
    19081 aggaggagat aattttatag catcatctga accagaagca cgtacgttac tcattttctt
    19141 gtttttacaa gggttgacta ccatatcatc ttttctggaa ttcataccaa ttatcatacc
    19201 ttcgtaaact tctacaccag ggtctacaaa cattacagct ctatcactta aggcattaag
    19261 agaatacccc atagtaacac caggtccttg tgctattaaa acaccatttc ctcttgaagg
    19321 tatttctcct ttaaattctt caaatttttc aaatgaacga actaaagtac cttctccacg
    19381 agtagcgttt ataaattcac ttcgatatcc taaaagacca cgagtaggtg ctaagaactc
    19441 tatttttaca tagtctcctt ctattgacat agactccatc ataccttttc tcatgtttaa
    19501 ttcatttata atagtaccag agtaaacttc aggacagttt acaacaactc tttctattgg
    19561 ttccattagt tttccatctt ctttatgcat taaaacttca ggtttagaaa caccaacttc
    19621 ataaccttca cgtctcatat tttcaagtag tatagataag tgaagctctc cacgtccaga
    19681 aactttgtat ccatcagtag tatcaagagg ttcaacttta agaccaacat ttacttcaag
    19741 ttccttttca agtctatctt tcaaatgtct agttgtaacg aattttccac tttttccaac
    19801 gaatggagag tcgtttacta agaagttcat agaaagagta ggctcttcta tttttatcat
    19861 ttccataggt agtggactat ctaaatcgca tatagtttca cctatagata tatcaggaat
    19921 accagctata acaactattt ctccactagt agcttcatca acttcaactt gttttaaacc
    19981 ttcatacaca gaaagttttg atacttttcc tttagataca acagaatctt ctctacatat
    20041 agcaacttgt gtattgtttt taagagtacc tttgtaaatt ctacctatac caagtctacc
    20101 tacataatca tcatatgcaa gagctgatat ttggaattgt agaggttcat tatcgtaatt
    20161 aggataagct tcaacgtgat ttacaatagt tttaaataga ggagaaaggt cttcactatc
    20221 atcatccatt tcaagtttag caataccttg tttagcaata ccatatatta taggaaattc
    20281 gcattgctca tctgttgcat ttaagtctac aaataaatcg aaaacttcat taactacttc
    20341 ttccgctctc tggtcttttt tatcaatctt gtttataaat aatattggtt ttaaaccgaa
    20401 ctctaaagat ttttgtaaaa cgaatctagt ttgaggcatt gggccttcac tagcatcaac
    20461 taatagaata actgtgtcaa cagttttcat aacacgttca acttcagaag aaaagtcact
    20521 gtgtcctgga gtatcaacta tgtttatttt gtaatcttca tagtttattg cacagttttt
    20581 tgaatatata gttatgcctc tttctttttc aaggtcgtta ctgtccataa cgcagtcttt
    20641 aactacttcg ttctttctaa aaacaccgct ttgagaaagg aaagcatcaa ccaatgttga
    20701 ttttccagcg tcaacgtggg ctataactgc gatatttata attttatgtt tttgtgacat
    20761 ttttgttgct cccttcgatt aaaataactt attaattata gcacaatata ttattaggta
    20821 caaggaggaa tatattaaat tgtattaata tagtttaaat tggataaaac tgttagtttt
    20881 gcatctgaaa attattctgt ttaaaaaaat tttttagaca aataataatc ttaatagata
    20941 aaaagattaa taaaagagta aaggatgata tatgttggaa gtaaccaaaa taataattaa
    21001 atattttgca agtgaaagtg atacttttat aaaagaagaa gtttgtaatt ttgaagaact
    21061 tcttaagtgg tctcataaat ttattgaagg taaaaagata gaagatgttt tgtatataaa
    21121 gtctaaagaa aactataaag taaatgtgat taagtcttta gaaattaagg aattggaaat
    21181 agtgagaaaa caacagatac caccgtacat gtagtattaa taatatataa aattaatatg
    21241 taatactcac aataggatat aaatggtata tatggtaata atttatatta aaaaaacttt
    21301 tataaagttt atatttgggt ataaaagtat taattagaca ttaattagga ggaacttaaa
    21361 tatgataaga gtatgtccaa actgttcaaa tgtggatgta aataagctaa aaactttggt
    21421 tggagaagaa aatgtaaaga ctggttgtat aggtcagtgt agagcattta aaaaagaagc
    21481 tgttggaata atagacaatg agcttgaaat aaaggaaaca gaagcagagt tttttgaagc
    21541 atgtaaagaa taaattttaa ataaaatata aattataata aatagagcat ctaaattgta
    21601 taagcattaa acaatttaga tgctctattt ttatatatac atttaattat gagtatactt
    21661 ttctattaaa tacaaataaa tataactaat acatttattt attaaaaaaa tattgattta
    21721 atatacctat agggggtata ataaaaatat agatttctaa ataagtaatt tatcaatatt
    21781 acatatcaaa ataaaacgtt acaaattagc tgaaaatata ttgaaagaaa ggaagatttt
    21841 attatgagtt caaataaagt ggtagaaagt tataaaatta caggtatgac atgtgcagct
    21901 tgtgcaaagg cagtagaaag agtaactaag aagatggatg gagtatatga ccaaagtgta
    21961 aatatagcta ctgaaaaact taaaatagaa tatgataatt ctaaggttaa ttttgatgat
    22021 ataaagcagg ttgtagaaaa agcaggatat ggaattataa aggaagaaag taataaaaaa
    22081 attgatatga aaattgatgg aatgacatgt gcagcttgtg caaaagctgt agagagagtg
    22141 gtaaaaaaat tggatggagt agaaagtatt agtgtgaata ttgcaacaga taaagctaat
    22201 atagactatg acccatcaaa agtaaaatta tctcaaataa aagcagctat tgaaaaagct
    22261 ggatataaac caatagaaga ggtaagaaat aaggttgatg tggatgaaga taaattgaga
    22321 aaagaaagag aaatgaagtc tttatttgtt aaatttatag ttgcaatagt atttgcagta
    22381 cctctgtttt atatagcaat gggacctatg ataataaagc ctatagggcc atggcctttg
    22441 ccagaaatta taaatcctat gacaaatact tttaattatg cattaattca gttaatttta
    22501 gtaataccag taatgatagc tggttataaa ttttatataa atgggtttaa atcacttttt
    22561 tctttaagcc ctaatatgga ttctttagtt gcaataggaa cattagccgc atttttatat
    22621 agtctatata cgacactaca aatagccaat ggacaaattc aaggtatgca ccatcatcag
    22681 ttgtattatg aaagtgcagg aataataata gcacttatct tacttggtaa atatttagaa
    22741 tcaaaatcaa aaggaaaaac atcagaagca attaaaaagc ttatggggct acaacctaaa
    22801 actgcaatag tgttagttga tggtaaagaa gttgaaactc ctatagaaga agtagagata
    22861 ggagatatac tattagtaaa accaggaact aaaatacccg tggatggagt tgtaatagaa
    22921 ggatatacat cagttgatga atcaatgctt acaggtgaaa gtataccagt agaaaaaaat
    22981 gttggaagta aggtgacagg agctagtatt aataaaaatg gtgttattaa gtttaaggct
    23041 gaaaaaattg gtggagatac tgctcttgcc caaataataa agttagttga agatgcacaa
    23101 ggtacaaaag cacctattgc taaacttgcc gatactgtat ctggatattt tgtaccaata
    23161 gtaattgcaa tagctgtagt tgcatcatta ttgtggtttt taataggagg aaaagatata
    23221 gtatttgtac ttactatatt tatatcagta cttgtaattg cttgtccttg tgcattagga
    23281 ttagcaacac caactgctat aatggttggg actggaaagg gcgcagaaaa tggaatcttg
    23341 ataaaaggtg gagaggcact agaatctgca cataaagtaa atacagtgat atttgataag
    23401 acaggtacta taacagaagg aaagccaaaa gtaacagata tagtattaaa taataatgta
    23461 aaagaagaat atcttatcaa gattgcttca agtgcagaaa aaggttcaga gcatcctctt
    23521 ggagaagcaa tagttaagta tggagaagag aagaatataa aatttgaaaa agttgataat
    23581 tttaaagcca taccaggtgc tggtatacaa gttactatta atgatgaaag tatattactt
    23641 ggaaatagaa agcttatgaa tgacaataat ataaagcttg gggatttaga agaaaaatca
    23701 aatgtattgg caagccaagg taaaacacct atgtatatag ctgtagatgg aaatttatca
    23761 ggtataatag cagttgcaga tgtagtcaaa gaaagtagta aaaaagcaat agaaatactt
    23821 catgatatgg gaataaaagt tgcaatggta actggagata atgcgaaaac tgcaaatgct
    23881 atagcaaatc aagtaggtat agatatggtt ttggcagagg ttttaccaga agataagtca
    23941 aaagaagttg aaaaactaca aaatcaagga aagtttgttg caatggtagg ggatggaata
    24001 aatgatgccc cagctcttgc aaaagcagat atagggatag caataggaag tggaacggat
    24061 gtagccattg aatctgcgga tatagtactt atgaagagtg atttaattga tgttccaaca
    24121 gcaattaaac ttagtcatga aactataaaa aatataaaac aaaacctatt ttgggcattt
    24181 ggatataata cgattggtat acctgtagca gcaggaatat tatatgtatt tggaggacct
    24241 ttattaaacc caatgattgc agcagcagca atgagcttaa gttcagtttc agtcgtatca
    24301 aatgcactta gacttaaaaa cttcaaggca tataagagag attagattaa taaattaaat
    24361 aaaatgtatc caaaagagct atctttaaat taaaaggatt aatttacaaa ttaagatagc
    24421 tcttttttca tgtaaaattc acaacaataa gataaaatat aagtaatata cgaaatttta
    24481 aataaaatag aaaggattga tagaatgaat tcgtcaatac ttgtaattga agatgattca
    24541 aatatacaag agttaatatc agaattttta agtgcagaag gttatcaagt tgatacagca
    24601 aatgatgggt tggaaggtat acaaaagttt aagcaaggaa gttatgattt agtaatatta
    24661 gatataatga tgccaaactt agatggttat ggagtttgta aaatgataag aaagtcatca
    24721 agcgttccaa ttatattttt aactgcttta aatgatgaag gagaccaact taaagggttt
    24781 gacttagaat gtgatgatta tataacaaaa ccattttcat ttaatcttct tataaaaaga
    24841 gtagaagcaa ttttaaggcg aagtaacaag actataaatg acaaatttat agtttttgaa
    24901 aaattaaaat tagatttaaa cacatatatt gcagagatag atggagaacc tatagaactt
    24961 acactaaaag agtttaatat attaaaagct ttgatagaaa agtatccaca agttataact
    25021 agggaaggtc ttttggatag tatatggggt tatgactatt atggagatac taggattgtt
    25081 gatgcacata taaaaaatat aagaaaaaaa atatcgttac catatattaa aactgtaaaa
    25141 ggaataggat atacacttga gaaggatatt tgataagtgg gaaaagttaa gtataaagta
    25201 taagttattt tcaataacga catcattatt aatagcgtta gctttaataa tatatctaat
    25261 tttatatttt ttattgccat catattatca tgagtataaa attgagtctc ttcaagaaag
    25321 tttaaaatct ttagtagata gttcaattca tttcgataca tatactttag aagaaagact
    25381 ttattatatg gctaaagacc aaaatttggc tattttatta aaagataacc aagggaaaat
    25441 tgtatatggt aagaatgaag tagttatttt aagatatagt aagtacatga ttaatagtct
    25501 tgaggatgag tatagaactt ctatacctat atatactaaa gatgcaaaag atggtccata
    25561 tactttagaa ctcgttatgc cattacaacc aattgacgaa gcaaacgaag ttataagaaa
    25621 actaatgcca tacatcatat caatagcaat attgatagcg attattggag catatatata
    25681 ttcaattgta ataacaaagc ctcttataaa tataatagag agtgagagag aacaggaata
    25741 tagaaggaag gattttgttg ctacaatatc acatgaacta aaaactccaa taaccataat
    25801 aagtggtcaa attgaaggta tgatttatag tgtaggtaag tataaggata gggatactta
    25861 tctgaaaaaa tcatatgaat gtacacaaga attaaaagat ttagtaaatg aaatgataga
    25921 ggtttcaaaa tcagaaatac ttgaaaaaga tttgaaattg gtatcaataa atataagtga
    25981 attattaaat agacttgtaa agagacaagt atttttaata gaagaaaaac atatgaaaac
    26041 tattttaaaa atagaagaaa atttggaaat taaagcagac caagagagaa taactaaggc
    26101 aatcaataat ataataaata atgccataaa atattctcct gaaaaatcag agcttataat
    26161 tagactctat gataaaaata aacgaataag taaaaagact tctaatcaaa gagtggtttt
    26221 agaaattgaa aatactggtg taactatcga gaaacgttat ttagaagaga tatttaatcc
    26281 attttataga atagaaaaat cccgttcaag aaaaactgga ggaagtggac ttggacttta
    26341 tatagtcagt caaattttta aaagtcatgg gtttgattat agcataaaaa acaaagaaaa
    26401 ctctgtagta ttcacagtag aatttaaaaa ttaattactt attataaaga atatataact
    26461 ttcaataata gttcatttta aaatcacaaa aaattcataa tgaaactgta ttatataaat
    26521 ataaagaagc ttaaaaccat aaaatacacc aactataatg atgagatttc cttacatcct
    26581 ccatataagt catcattata gtaacccaac aattaagtta ctatgaattt aaaaaataac
    26641 accgagcata taatctatgc ttagtgttat ttttattttg aaataaaaaa tatttaattt
    26701 attgaaatgt atagatttag acagtttaaa ctatatttaa gacttaaaaa ttataattga
    26761 tattacaaat aaatatatgt actttgggaa aaataaatat aggaagtatt atatttacag
    26821 aggaggtagt tttgatggat agattaaaaa gagatatgaa aaatatgaaa gaagatttaa
    26881 aagaaggtgt taaaaagaca gcttatgtta tgaaaaatac agctgaagat ttgaaagatg
    26941 atgcacaagg tgctatggta aacttagaaa tgaaaaaaga tgagatgatg gaaagatatg
    27001 aacaaaagaa attttctaaa gaattagaga agcaaatgaa gaatgaaatg aaataagctt
    27061 ttatttatga ataacaaatt attgtattca tataaaaagt agccagtaat attaaatagt
    27121 ttatttaagg aaatagactt tctaaaaata actgtattag atttagaaag tctatttcaa
    27181 attagtttta taaatagaca taaggataaa gtagatgtta tagaactaga ttttaaaaaa
    27241 tagatactaa ggataaaata aatattatag aaatatgttt ttaagaatag ttatcaaata
    27301 aaaatttata tttataagaa atcctataaa atatataatt aaacttataa aacatttaca
    27361 ttaaattctg ataaaatatc tactatatca ggagtaggcg ctttttctgt aattatagaa
    27421 ctaatatctt ctaaatgagc aaacttgaaa tttccatcaa atttaaactt tttatcttcc
    27481 ataactataa atactttttt acttgaattt attatagcct tcttcgtgag accatcttca
    27541 atttcaaaag ttgtaagtga agagttgaat acatctactc cacaacttcc cataaaagtc
    27601 ttatcaaact tatatttcga tataaactct atagttggag taccgacaaa accgtctaaa
    27661 ctgagattta ataaacctcc agtggaaatt atatttaaat tatttggttt tgaagtaact
    27721 acatttagta tatccaacat atttgtaaca agtgttactt ttttattact ttcagctaac
    27781 aactttgcaa gcaagatgtt aattgtagag atatctaaaa atatagtttc tctatcttca
    27841 attaaattaa atgctttttc tgctattatt ttctttgttg gaatattaat ttcttttctg
    27901 tcttttgtat cctgattctc tagtgtttct ctagctagta cagctccccc ataaattctt
    27961 cttattgaag aaatcttttc tatatttttt aaatcttttc ttatacaatc ttctgtaaca
    28021 ttaaatttag aactgagctc tttgacagta actctacctt ctttttttag gatatttaat
    28081 atagcttgga ttctttcttc tgcaaacatt ttctacctct tttcgcaata tagtattata
    28141 gtaaatatta taagataaaa tacaatatat caactatttt aacatgaaat acaaaattaa
    28201 tttaatataa aaagtatgtt ttttctaact atatatttag aatttagtaa ataaaaaaat
    28261 tataaaacta agaaggaaaa gcaaaacaat aataaaaaat aaaaaacaat aagcaaaatg
    28321 ttgaaaataa taccaaatca atatataata agaataaaga aagattaaag ggggatattt
    28381 taatgcaact aatcttagat acaggtaatg tggaggagat taaggagtta tgtacttgtt
    28441 taccaataga tggtgtaact acaaatccaa gtattgtttc aaaagaaaaa aagaatttta
    28501 agcaacttat aaatgaaatt ggtgagatta taggtgagga tatgcctata catgctcaag
    28561 tgttaagtac aaagtatgaa gaaatattag acgaagcatt atatataagt agtttgagaa
    28621 aaaatatata tgtaaaaata cctgtaacac aagatggttt aagagctata aaagaccttc
    28681 acagaaaagg tgtaaaaata actgctactg caatattcac tgctcatcaa ggttttttag
    28741 ctgcaaaggc tggagcaaat tatattgcac cttatgtaaa taggcttgat aatatatctg
    28801 gtgatggagt agctatggtt tcagaactta taaaaataat agatacttat aaaatggata
    28861 caaaagtact tgcagccagt tttaaaaatg cacaacaagt tatagaatta atgcaacatg
    28921 gggtgcatag tgttacagta ccatatgata tttgtaaatc tatgatgaat catccattaa
    28981 ctgattggag tgtagataag tttatagagg attgggagaa tacttttgga aaaggaagta
    29041 aaacaaataa tatttagtat tatggtaaaa gagtagtttt gtccaatttc acaagaactt
    29101 atataaaaag atgaaaatat gaattttctt tttaataatt tcgttattat cttaagttaa
    29161 ttcatatttt catctttttt agatttctag tcctataaat ttccaccaag ggaatgttat
    29221 acatattatt ataaagtagg ttaaaggaat caaagttaaa ccgtatttga aaataacctt
    29281 gctattatac agattttcac catgaccaac cattattgta gcatgatgaa atggtaatat
    29341 gtactgtatg cttactataa tgtagacaaa tagacataaa gtaacactat tttcctttag
    29401 tatatgtaaa cttccaagta atggtattac tacagatgat gtagtgacag cacttccaag
    29461 acatatattc aagattattg tgagagttat caaaaacaat attgaaataa tttctgaaga
    29521 gtttggtata aactttatca aataatttcc cattatatct acaactccag agtactttaa
    29581 cactcctcca attgaaaatg ctgctataaa aaaaataagg accttccaat ttatttcttt
    29641 taaagtacta aatccaacta tttttcttag taataaaaga agtacacaaa ttgacattat
    29701 aattaatgtg tttatgttat gtatgaactg agttaaaaac ataaaaaaca ttattcctag
    29761 gcataaaaat acgtgttttt gctctttgtt tagcaaatta aattcttttt ttaaattaga
    29821 atatgaaaaa tgaagtttat taccctcaag attttcatta gaaataaatt ttattgaatg
    29881 caattctttt ttaaagacaa agataaataa aaaataagtt ataaaacaag taattatagt
    29941 tggaacagac atataaaaag cccattgacc ccaatttata ttacaatttc caagttctag
    30001 tacaacataa tttagaaggg tgtctccatt tacaaaaaac attgatgtaa aggtagatgc
    30061 tgtaaatata ctaaataaaa gtatagattt tgaatcttca gttatctgtt gttcttttaa
    30121 aaactccttg taaaaagcag atacaagaat aacccttgga aatggttgtg ggataaaaaa
    30181 tattaaaaga atacctaaaa tatacgataa aagaatcatc tttttagggg tatttacagt
    30241 atttaaaatt aacttctcag aaataatttt tgcgacacct gtttttgtaa ctgcattagt
    30301 aattatgtat gcaagaatta ttatgtaaaa attttctgta aataaaaact gtaaaataac
    30361 ctttattggt gcaatgttaa atataaacgc tagaattaca aaaaacaatg caacaaaagt
    30421 tttttcaact gagtctacag cccatatcaa gatagttaaa aaagataagc atatagaaaa
    30481 ttttatgttg aaactgtaat taagagagaa gtagagaatt atggtaacta taacagtcat
    30541 ataaaattgt tttggcttaa gaataatacc catttttata ttcacctcca taatttatta
    30601 tatcataatg gaggtgaata caatgaatgt gaatacattt tataaaaaga ttattcattg
    30661 attctatgat ttacaatagc tttagttttc caataccctt tcttatagta gataactgta
    30721 acaataagac ctaaagtcca accaaaagga atacccatcc aaattccgtc tgttccaaaa
    30781 aatttagaaa gcatataaga agctggaagt cttccaagcc ataaagatac tattgagctt
    30841 ataagtgcaa acatggaatc accagcacct ttcattgcac ttgaaagtac aaaagaagtt
    30901 ccaataaata aaaagaatgg tcctattata aataagtaag aagagccaat tttaatgaca
    30961 tctttatcag tattgaatag agcaattaga ttttccctaa atagcaaaat taaagcaata
    31021 actgtaactg ctaaaactaa ggtcattttt atagattctc gaatgccttt tttaaccctt
    31081 tcattttctc cagcacctat gttttgagca acaaaagtag aaacagcaga accaagattc
    31141 ataataggta agcttataaa attttctatc ctaagaccag caccaaaagc tgccatagca
    31201 gatgtaccat aactattaac taaaaattga agagtcatat ttccaattga aaacaacatt
    31261 tgttgaattc cacttggaag tcctaatcta agtccatctt taaatatttt gttatcgtat
    31321 acaattcctt tgattttaaa tttaagcact tcatgttttt tatttaaata aattatactt
    31381 attataaatg atactgcctg agccattata gtggcaagtg caacgccctc aacacccatt
    31441 cttagcacta caataaaagt taagtctaaa actatattta gaattgtggc tattatcaga
    31501 aaataaagtg gagttactga atctccaagt cctctaagta ttgcacttac tgaattatat
    31561 ccagcagaaa ataatattcc actaaatatt atagtaagat acaattttga ttgagcaaaa
    31621 acggattctg gtgtattcat aagcttaagc attgggccac caaatactat tccaagaata
    31681 cttattaata tagaaccaat aaataaaagt atatatgtag tatcaatagt agcttttacc
    31741 ttttttaaat ctcctgagcc ataaaattgt gacactaaaa tagaaaatcc aaggctaaca
    31801 cccataagcg ctgccaccaa taaaaacatt atagggttag ctccagagac tgccgccatt
    31861 gcttcttttc cgataaatct accaactatt atactgtcag ctgtattgta tagttgttga
    31921 aataaactac caataagcat aggcatggca aaaaagaata tggattttcc ctcatgacct
    31981 gtagttaaat ctttcacctt attcctccaa ataaaaaaat tattaattta ttatagtata
    32041 atcttaacat aaactttata tccaaactat aaataaattg tatcaaaata tcatatattt
    32101 ttttaaaatg taaagaatat aattataatt tgaatttaat aaatcaatat ttaatataat
    32161 cgaatattaa tacaaaatca atacaatata tacgtatata ttgacaaaat taattatata
    32221 aattaaaata atattcgtaa agaaaaattc atgttttgta ctgtataaca tataattttg
    32281 acaatatggg tcataagttt ctaccggaat accgtaaata ttctgactat gtatactatt
    32341 atttagttaa ttaaatattt aattaactga attatgaagg atacggctca gcttatcaac
    32401 tactgtgtcg tttttttgta aaatttaata ggaggtgttg ttatgcaaac aacaaacagt
    32461 agtactatgc agaaactttt tccaattttg actaataaaa atgtcgacat gaagaaggaa
    32521 ataattgcag gagtaactac ttttttaact atggcttata taatagctgt aaatccaaat
    32581 attttatctg agacaggcat gcctgcaggt gcacttgtta caggtacttg tttagcagca
    32641 gcatttggat gtattttaat gggtgtagtt gctaaccttc cttttgcttt agcatcaggt
    32701 atgggtctta atgcattttt tgcatataca gtagttttac aaatgggtgt tccttgggaa
    32761 gtagctctta cagcagtatt tgtagaaggt attattttta tagtattatc agtaagtgga
    32821 gttcgtgagg ctgttgtaaa tgcgatacca aaaaatatga aattagctgt tacaggtggt
    32881 ataggaatat ttattgcact tataggtcta gttaacagtg gaattgttat tggagaccaa
    32941 gccactctta tcaaaatggg tagatttaca ccagcagtaa taataacttg tttaggatta
    33001 ataattattg ctgtattaga taaaaaaaga gttaaaggtt ctatactttt tggaatagta
    33061 gtgagttcat tacttgcttg ggcatttgct tttatgaatc cagagtatgc acaaaaatta
    33121 ggtatatatt tacctggtgg attatttaaa ttcgaaagtt tagcaccaat agcaggtaaa
    33181 atagatttag gatatgtact acatccaaca aatataggtg gttttttagt agtagtttgt
    33241 acatttttat ttgttgattt ttttgataca gtaggtacat tagttggtgt ttgttctaaa
    33301 gcaaacatgt tagatgaaaa agggaatgtt cctaatgtag gtagagcctt acttacagat
    33361 gcggttgcaa ctacagttgg tgcaggactt ggagtatcta cagttacaac ttatgttgag
    33421 agttcaacag gagttatcgc aggtggaaga actggatgga cagcaataac agttggaatt
    33481 ttattcttag ctgcaatgtt tttctctcct gtatttatag caattccatc atgtgctaca
    33541 gcaccagctt taatatatgt tggatattta atgcttggta cagttaagga tatagagttt
    33601 gataatataa ctgaaggtgt tccagctttt gttactattg cttgtatggc attaacatat
    33661 agtataggtg atggtttaac tttaggtata ttaacttatg ttttcgtaaa tatattttat
    33721 aatatatttg gagctaaaaa ggcagaagac aaaaaacatg tttctgtagt aatgattgtt
    33781 ctggcaatat tatttataat aaaactttgg ctattataat aggtattatt taaaatttta
    33841 atttaatata aaataaaggg ctataattta ttatcaattg tgatgataaa ctacagctct
    33901 tttgtatttg ttgtattttc gtatttattg tattatttaa taatgtctat tagttctcca
    33961 ttttgtaaag ttttaggtgt aattactata ctgaactctt tttgcaaatc ttttataata
    34021 tctaattctt tttttgttat tattgagatt gtgttaccac ttcgatttcc tctagaagtt
    34081 cgaccacatc tatgcaggta ttcattttta ctttttggaa aatccaagtt aaaaacatga
    34141 cttacatcca caatatctag tccacgagca gataaatcag ttgtaattaa aatctttgct
    34201 ttaccaagtt taaatttatt tattgcattc tttctatctt ctttttccat atttccaaaa
    34261 attcctattg ctttgtaatt atgataattt agttttgata ctaggacttc tatatttttt
    34321 tcattattta caaatacaat agcttttttt ggatttgtag ctgctaatgc ctttctaaga
    34381 aaagtaaatt tatcccttat ctcacctaat aaatatgagt gattgatgtt aggatttatt
    34441 tgtgattttt cctttgtttt tattatttca aactccttca taagtttatc acaaattttt
    34501 atagtgctat cagtaagact tgcagagcat cctataattt gtctatctct taacgttgtt
    34561 cttattatgt cttctataca agttatattt tttccattca atagattgtc cacttcatct
    34621 aagactatag tttttatatt atgtgatttt agcttctttt gttttatcaa gtctaaaact
    34681 cttccacaag agccaattac tatgtgtggt tttactgctt ttatattttt tatttgtttt
    34741 tgtatattga cctccccaat taaagctaaa gaagtaacgg agagttctgc atttttagcc
    34801 aataattcaa cctggtttgt aatctgcatt actaattcat gcgtaggtgc aagtataaga
    34861 gcttgtgttt ctctttttga tgtatcaatt ttttcaaata taggtaaaag gtacgctagt
    34921 gtttttcctg ttccagtctg tgaattaatc aataaatcct tattttgaat tatattccct
    34981 ataacaagtg actgaacttc tgttggagaa gttatgtctt gttttttaag tccatctatt
    35041 agagtggaac ttatttttaa ttgttcaaat gtattcatat tttgctcctt atatttaata
    35101 attatagtca actatttttt attatacatt gtttattcaa atcgaactat atattctttt
    35161 ataattatgt gtaatttgaa agtaaatatc aattatattt atacctttat atttctgata
    35221 cctttgcatt ttatagattt ctaaaataaa caaataaaag ttgtaattgt ttgatatttg
    35281 ttatatatta tatataacaa atatcaaaac tataatatgg agggaaatta tgttaaaagt
    35341 aatcaatgta tctaaatcat ataaaaataa aaaagtagta agtagtgtct catttgatgt
    35401 aaatgatgga gagctttttg ggtttatagg acataatgga gcaggtaaaa ctactactat
    35461 taaagcaatt gttggaatac acgattttga agagggagaa gtactaataa attctaaatc
    35521 tataaaaaaa cagcctgttg aatgtaaaaa ggaaatggca tatatacctg ataatccaga
    35581 tttatacgag tcattaacgg gtatacaata ccttaatttt atagctgaca tatttgaagt
    35641 tgccaaagac aaaagagaag agttaataaa atattattca aataagtttg aactcaataa
    35701 agcattagga gatttaatat cttcatattc gcatggtatg aaacaaaaat tagctataat
    35761 ttcggctttg atacacagcc caaaaatctt aattcttgat gaaccttttg taggtcttga
    35821 cccaaaagct tcctttatat tgaaggaaat tatgagggag ttttgtgaca aaggtggttg
    35881 tatatttttc tcaacacacg ttttagaagt tgctgaaaaa atttgtgata agattgccat
    35941 aataaaagat ggaaatataa ttgcttatgg aactacagaa gaagttaagg gaagtaattc
    36001 acttgaaagt atctttatgg aattaataga gaaataaaat gttttttata caatatagtg
    36061 tctaaagtga ggaatgataa aatatgagca atctaagtat attaataaaa actaatataa
    36121 taaatgaatt taaattaaat gcgttaaaaa aagctgatag tagagaaaaa caaaaaataa
    36181 tggggatgat actttcagtt gttattataa cagggttatt gattttttat gtaactagta
    36241 taagtctttc tttagttgat attttaaagc aaataaatca gatggaaatg ctacttatat
    36301 ttggatttgg attatcaaca ttaacaacta ttgttacatc attatataaa acgtcatcat
    36361 atctgtttca agcaaaagat ttagaccttt tgactagttt acctataaaa gaatctactg
    36421 tactagcaag taagatatta atgttggttg gagcaaacta tttattttct tcaatatgta
    36481 tgattatacc agcagtggtt tattttttta attctgatgt aagtataacg tatttccctt
    36541 atttgatact gctattttta gctttaccat tattaccaat agttgcttca tcaataattt
    36601 ttatgtttat aggacagata tcatcaagaa taaaatacaa aaatttaata ttaattatag
    36661 gtagtattat attgatgttg ctttatactc tacttatgac aagacttaac tctatgtcgg
    36721 ttgagatgtt aaagaatagt gtatctattt cagagacgat tagaaaaata tatccaccta
    36781 tatattattt tgttgacgct cttaaaacag gaagtgtagt ttccttttta gcatttatag
    36841 caatttcaat aataccattt tttatgtttg taacattatt tgcaaaaaaa tttaaagata
    36901 taaatgctaa gatgagtgaa ggatataagt caaaaactta taaatttaag agccaaaaaa
    36961 cttcaagacc ttcaaaagct ctattaaaaa aagaatttaa gagatatact tcttcattta
    37021 tatacttttt aaattcatct gcaggtttgt tattcctaat aataggtaca attttaatat
    37081 tattatttgg agcagataaa gtgggtgagt tactgaaatt gaatatagat tttaatttta
    37141 taaaaataca attattggga gtattcttct ttataatagt aatgaattgt acaacatact
    37201 gttcaatttc tcttgaagga aaaaatttat ggatactgaa atcttctcca atagatgaaa
    37261 gagaaatatt ctggtcaaaa atattgatga attttttatt gaatgcacca ttatctattt
    37321 tatgtttaat attagtatct ataagattag gttttgaaat tcagtttatt attgtatcaa
    37381 tctgtttgat tgcaagtttt tcaatgtttg tggcattgat gggattatta tcaaatttat
    37441 tatatccaaa ccttgattgg aaaaatgaga tggctgtagt aaaaagaagt gcaagtatga
    37501 taattacaat gttagtatca ttagcttacg taattatact tggaggtata tatgtattac
    37561 ttggaatttc gtttttaaat atatatatta ttttggcaag tatacttact tttatattag
    37621 attttatgat atggagaatt atttctacta aaggagtaag aatatttaaa aatttatagg
    37681 tgtatttatg tcaaataaag acttatcttt tttagtcttg caaataatag gttaagtagt
    37741 atactatgta tagtgatatg aaaaaattta ggagaaaata aatgagaaaa ttatccaaaa
    37801 gagaaaaaga ttttattcaa tatggatttt tattattttt gatatgtatt actacttatt
    37861 tagtattaac tactttagat ataaaactaa tacctaaaat tataaggcta gtaaataaga
    37921 cttatatatt tcttggcata ttgacaatta tagtatatat gataattgaa tctattgtaa
    37981 ctcatttgat aataaatgca gttcaaaaaa caaaagtaaa atttattggt attaaaatgg
    38041 ctacaatggg attttactat aacttagtta ctccatttgc atctgggagt caaccaatgc
    38101 aaatatatgc acttacaaaa tatgatgtaa gccttagtaa atcagtggct atagttacta
    38161 ataaaactgt agtatttcaa agtacagtta ctgtattttg tggaatttta attttgctaa
    38221 ataagtcatt actgatggag caagtacatt ctgtgaaagt cttgataact tttggaatga
    38281 ttatgaatgt aagtatgttg ttaggtggac tattaatagt atttagtcca aaacaagtaa
    38341 aaatgatagc agaagttttg attaattttt tatctaaatt taaaacattt aaatttttag
    38401 attcaaaacg tgatagaata aatcattata ttgatgatta taattattct ataaaaatat
    38461 ttattaaaaa tgtaagaatc ttagttttaa gtatattact tactgtgtta caattaatcg
    38521 catatttcag tatagtttat tgtgtgtata aagcctcaaa tttaagagga gtttcatatg
    38581 tacatataat gacattacag gtctttttat atatggctat atcaccaatt ccaacaccag
    38641 gaaatgttgg agctaatgag gttacatttt ttactatgtt ctccaatata attccaaaag
    38701 aattattggg gtactctgta ctcttatata gtgggtttgt atactatttt atattaatag
    38761 tttcaggttt atttacattt ggaacgcatt atacattaaa ttcttggaaa aaggaagata
    38821 aagtaaattc taatttagat aaggttattg aaaaattaaa ttaataaaat aattagggaa
    38881 attctatata taaatatggt gttgagtaag ctatattata ttgagatatt tccctttttt
    38941 gattaaaatt atagaaattt gaaataataa gtaataaaca gaaaaagtga tattgttttg
    39001 aaaggagaaa ctatgaaaca agataaacaa aatgaaaaac aaagtgagat ttctaagata
    39061 aaacaaagca atgataataa acttgaaata gctcaagaat tacatgtaag taaaaatata
    39121 gggaatatgc ttggatatag aatagataag aaaaaaatga atagaccaag ttaatgaaaa
    39181 tgttgaaaat ggtacatttt aaaaaatata tataatgaaa tgttttattg ttaaatttaa
    39241 acttatttta atggaggaaa aagtcgaaaa atatctaaaa agatatggat ataaaaaata
    39301 ttaatatata tatactataa acttgacaaa atcaaccttt taataactag caaaaaatag
    39361 caaaattata taagcgttat ttaattatca aaaatgaaag ctaaattgca tgtcctaaaa
    39421 aaaatgattg ataacattta tttgtgtgct ataattatat agtaaaacaa taagtatatt
    39481 gcataatgta tgcaaatcgg gaggagagac ggacatggaa gcatctatac acacaattgc
    39541 cagcaataat ttattgataa tttttgctat tgtaagtata actggaataa tttgtagtaa
    39601 gcttagtgaa ataataaagg ttccagatgt agtgttatat ttacttgtag gtattttaat
    39661 aggaccatca tttttaaaat ttatagatat tcgtggattt caaatagaaa atcaactaat
    39721 acttacattt ggttctgcat ttattttata tttaggtgga aaagaaataa gtttaaaagt
    39781 attgagaaat gtgaagatat ctgtattctt attagctact ttaggagttg tgatatctgc
    39841 ttttataatg caacaagtaa taggatttac ttttgggata agtgcaatga ctgctttact
    39901 agcaggaact ataatagcat caacagaccc agccactctt gtacctatat ttaatcaggt
    39961 aaagataaag gatagggtaa aacaaactgt aataagtgaa tcagctttta atgatgcaac
    40021 aggagctata ctaacatcag cagtgttggc tgtaattttg tcaaataaat tttcattagg
    40081 tgaaaatatt tatgaactgg ggacaatggt tattgtcgga gttttagttg gtttaattac
    40141 aggaatactg cttttgaaat tagttaatga taaaccttat ggaatattta aagattttgc
    40201 accaataata tctgttattt cagttgtagt tgcatatgaa ttatctacaa aattaggtgg
    40261 aagtggatat atgtcttgct ttattgtagg tataataact ggtaacaaga aaaactttaa
    40321 aatttggtta agtcaaaaat cttatgatgc agatttttat gttgctgaaa ctttaggtac
    40381 tatttgtcgt atggcaatat ttataatatt gggtagccaa gttaatttgg ctcagttaag
    40441 taaatatttt atgccatctg taattacagt attagtatta atgtttatag caagaccact
    40501 ttgcgtttta gtttgtacac ttgtagacag ggaagcaaaa tggagtaaaa gtgaaatatt
    40561 atttatgatg tgggtaaggg aaacaggcgt aataccagca gcactttgtg gtattatttc
    40621 agcaatgaaa gttcctggat acgaagtgat ttcatctgta gtatttatga ctatattaat
    40681 tacattagta atacaaggaa gtactacaaa attagtagct aaaaaacttg gattattaga
    40741 agaagaagtg ataaatataa gtgaaaaagt atcaactttt taaagttttg ctttaaaata
    40801 gtacctgtta atggctattt taatattgtc taatgatgat tattgaaata gtcatttttt
    40861 tatgtataag taatttacag aatttacata ttagacatat ttattatcaa aatttgttga
    40921 agctatgata taattagttg tatttaaaat aagaatagca aataagggag gaaatttatg
    40981 tttacggtta tggatattgt acagccagat acagtagaag aagcgtactc aattttaaat
    41041 aaaagaaaaa ctaaccaagt aattggtgga agtgcttttt taagaatggg gaaaaaaaga
    41101 ataggaacag gaatagaatt atctaaatta aatttagatt atataaaaga gtatgaagat
    41161 tacgttgaga ttggttctat gactactttt agaacattag aaacaagttc cataataaaa
    41221 aataattttg gaagaataat agaagattca gttaaaaata taataggagt tcagtttaga
    41281 aatgtagtaa cagttggtgc aacagtattt tctaaatatg gtttttctga cttgatagta
    41341 gcattacttt cattagatac ggaagtagaa ttatataata ttgggagaat tagtcttgaa
    41401 gagtttctaa atagagatta tgagaaagat ttacttatta agatatacat aaagaagaca
    41461 aataagaatg cttcttataa atcacttaga aatgcaaaga gtgattatcc aattctaaat
    41521 gtatctgtat caaaacatat ggaacaattt aagttatgtg taggagcaag accgcagaaa
    41581 gctacgattg caaaacaagc tagtgaattt ctatctaaca atgaaatcaa tgaaattaat
    41641 atagataaag cagtagaaat agcatcagaa gaactaactt ttggttctaa catgagagca
    41701 tctagggagt atagaaaagc tatgagtaaa gtacttttaa aaagagctat aatggaggtt
    41761 atttaatgtt agtaaagatt aatataaatg ggaagaaaaa aagtgttgat atagaaccag
    41821 aagaatatct ggttgatact ttaagaaaag ttggtaattt aagtgtgaaa agaggttgtg
    41881 acacaggctg ttgtggttta tgtacagttt taattgacaa gaaacctaca ttatcctgtg
    41941 caacactgac attgagagct ttagataaag aaataactac aattgaaggt ttagaaaatg
    42001 aagttaaaga atttagtgaa gttttggtaa aagaaggagc tgagcaatgt ggtttctgtt
    42061 ctcctggctt tatacttact gtacttgcaa tgaaggatga gcttgaaaat cctacagatg
    42121 atgaaataaa gcattatctt acaggaaatc tatgtagatg tacagggtat atgggacagt
    42181 taagagctat caaaacttat ctggaggtaa aatagaacat gaatatagtt ggaaaaggaa
    42241 tcaagaaaat agatggaatg agtatcacaa caggaaagcc tgtatataca gatgatttat
    42301 cagcaaaaaa tgctttggtg gtaaagatac ttagaagtcc tcacgcttat gcaaaaataa
    42361 aagatataga tacatcaaag gcagaaatgg ttgatggtgt tgaatgtgtt ttaacatata
    42421 aagatgtacc aaaatctcga tttacacttg ctggtcaaac atatccagag ccatctccat
    42481 atgatagatt aattcttgaa gatgttgtaa gatatgtagg tgacgaagta gctatagtgg
    42541 cagctataga tgaaaaaact gcaattaaag caatgaatct tatcaaagta aagtatgaag
    42601 tacttacacc tgttttggat tttgaagagg caataggaaa taaaactatg gtacatgatg
    42661 aagatagaca ttgtaacttt gatataggta tgcaaagaga aaaaaatata gtatcccatc
    42721 atgattatac aaaaggtgat gtagaaaaag tattaagtaa ttgtgatgta gtgattgaag
    42781 aaacttatta tactcaagct caagcacatg caatgatgga gacgtatagg gcatacaatt
    42841 atttagacca tatgggaaga ttggttgtag taagttcaac tcaaatacca tttcatgtaa
    42901 aaagacattt atctcgtgca ctagaaatac cagctagcaa aattagggtt ataaaaccta
    42961 gaattggtgg cggatttggt ggtaaacaaa ctgcgtgtgt tgagattttt tctgcaattg
    43021 ttactttaaa aacagggaaa ccagctaaaa taatttatga tagaaaagaa acttttaatt
    43081 gttcaacaag tagacatgca atgagattaa aagttagact aggtgctaca aatgatggca
    43141 taataaaggc aatagatata aaagcacttt ctgatacagg agcatatgga gagcatgctt
    43201 ctacaactat tggtttggtt ggagaaaaaa ctttaccaat gtataataaa gttgaagcaa
    43261 caagatttat tgcagatgtg gtatatacta ataagatgcc agcaggagca cttagagggt
    43321 atggagcatc acaaggatgt tttgctgttg aatcaactat aaatatgctt gctaataaat
    43381 taaaaatgga cccaacagat ttaaggttaa aaaatgtggt aacagaaggt gaaactacat
    43441 ttgcatatgg taaaacttta aatagtgtcg atttaataaa atgtataaat aaaggcaaag
    43501 aacttattgg atggaatgaa aaatatcctt gtaaacatct tgataatgga aaaattagaa
    43561 gtgtgggtat ggcaattact atgcaaggtt ctggtataca aggtcttgat aagtcttcag
    43621 ctgaaataaa attgaatgac tgtggagatt atactcttat gataggttct actgatatgg
    43681 gtacaggaag tgatacgatt ttagctcaaa tggctgctga ggttcttgat acaagcattg
    43741 aaaatataac agttatatca gctgatactg acttagttcc atatgaccca ggttcatatg
    43801 cttcaagtac tacttatgta acaggtatgg cagtagttaa ggcagctcaa gacttaagag
    43861 aaaaaataat ttctgctgga gcaactaaac taggtgttga gaaggatgaa gtagaatttg
    43921 atggtataaa attaactagt aaaaaaggta gcactttatt attcgatata gcagttgatt
    43981 ctacaattgg tccagatact aatcaattaa taggtcttgc ttctcatggt agcccagtat
    44041 ctcctccacc ttttatagca ggttttgcag aaactgaaat tgacacagaa actggaaaag
    44101 ttgatttagt aaattatgta gctgtagtag attgtggaac ggttataaat aaaaatctag
    44161 ctaagataca agttgaaggt ggaattgttc aagggattgg aatggcatta tttgaagaag
    44221 ttagatacac agaaaaagga agcatggaca caaatacatt tatgcaatac aagattccag
    44281 ctagatgtga tattggaaat gttaaagtag attttgttga aacttatgaa ccaactggac
    44341 catttggtgc taaatctgtt ggagaagttg ttataaatac acctttacca gcaatacaag
    44401 aagctgtgtt taatggaatt ggtgtaagaa taaatacact ccctattaca cctgaaaaag
    44461 tttttatgga aatgaataaa taattattta tgaaaattta gactagtttt acatgttaaa
    44521 caaccagtta tgtcatacct gttgaaagat atttaataag tagttattat aatattatga
    44581 attttactta taaaatacaa aattaaataa ggggatgatg ttttggctgg taatctaaat
    44641 aatatgagag cagtaaataa ttttagagga gataagaaca ttttagaatg tttagtcagc
    44701 tttgagggtc gttcaataag tcagagaaaa gtaagggtat tttttaaaga aaaacaaaat
    44761 caaatagaaa ttgattttgc agaagaggaa atttctaaat tggttgaaaa tgttgtttta
    44821 aatacatcat atcaagaaat gttatatgat gaaatagaga aacaactgga aattgattgt
    44881 ataggtactt ggatgatatt atctaaatta aaagatggta gtagagttca ctgattttaa
    44941 aataaattat tagagcctaa ttttaaggct cttttttgct gtttttaatt aacaatagaa
    45001 aatttatctt tagtttgtat ataattttaa tatcatatat tctatatata taaaattgaa
    45061 tttgtatgta ttatattgta taatataaaa tgaatttgga aaatagttcg ctaaaataat
    45121 ttgtttttat aaaattactg tttaagttta tagattttgt ataaaataaa gttatgttat
    45181 taattttttt agaaataaaa cttttactag gagacagata tgagaaaaaa tagtattaat
    45241 atagcactaa ctgcagcaat tacagcaatc tatgcagttt taacattatc attgggattt
    45301 ataagttatg gaccaataca atttagggta gcagagatta tgatgctttt ggcattttta
    45361 gataaaggat atatagtagg tcttacatta ggttgttttt tagcaaatgt aataggacca
    45421 tatggtgtac ctgatataat ttctggaaca ttagccacat ttataagtgc aagtatgatt
    45481 tatattacta gaaagttagg taaacaaaat aaaagtactt tagttatagc ttctttatgg
    45541 ccaactgtta taaattcgat tgtggttggt ctaatgttaa atgtattctt tgggcttcca
    45601 ttaattctat ctatgataca ggtaggtttt ggagaatttg tagtagtaac aattgtagga
    45661 gtaccatttt tctgcttttt aatgaaaaaa tataaaaatg tcattaatat taaattttaa
    45721 atagtgtata gtaatttaat taattgagag tattattagt gaaaagaggt gtttatttgt
    45781 cgaaggtaaa aagattgact gatgtttgga tatatattaa tgataagcaa aagtttacaa
    45841 taaaagagtt gtcagaggaa tttaatcttt cagctaaaac aatacaacga tatttaaaag
    45901 aattaaataa aatgggactt ccaattcaag cagaacaagg tagaaatgga ggttataggg
    45961 tgctaaataa tagctatata cctcctgtta tatttacaga aaaagaagtt atgattatac
    46021 tatttgcact taagtcactt cagatttata attataagtt aatggaaata gaaattaatt
    46081 ctataatgag aaaagtaagt tatgaacgta aaagcagtat aaaagtaggt atagaaaata
    46141 ttaaaagata cattggcttt gtagctaatg atactaatga tggagatttt aagagtagta
    46201 atgtaactga gttttttaga gcttcttcag aatctctaat tttaaatatt aagtataagt
    46261 gtggtaatca gattttggaa aaaaacgtat gccctatagg tatatattta aataagggag
    46321 catggttttc accagcatat gattgtaaaa gtgataaaat aatattagtt catatagata
    46381 atataattga tataaaaaga acaggagaaa gtaaaaaaat acatataaac ttggaagaat
    46441 ggttacatga agtatataac aatttatatg gaaatagttc aactactaaa aaatttggtg
    46501 aaattattta tctaaatgta ttattaacta aagaaggtgt ttctaaaata aaggacagtt
    46561 cttggaattt agatatggag ctaaatgaag atggtagtgg aataattagt acattcataa
    46621 aggttgaaga tatagattgt tatgcttcga ttttattttt tattggaaat aatgctaagg
    46681 ttatagagcc aaaatttttg aataagctac tttatgataa ggccaatgag ttaagatatt
    46741 tttatgaaga aaatatggta taatatttag aaatgttgaa attaaataat tattaaggag
    46801 atatacgtta taatggaaaa ttttaataag aatgctaaaa taattggtat tggagttgaa
    46861 ggtattaata taataaatga agtagaagaa aaaataaaag caaatatgga tatagaaaaa
    46921 ataaacataa atcaagagat tgaaaaagaa tatgttagaa gtcttttaga tggtgtagat
    46981 atattatttt tgatatattc atctgaagat aaacatatta gagatattat aaaagctgtt
    47041 tcatatatgt caaacgaaag aagagttcta tctataggaa tggattgttc agagaaagaa
    47101 aataaagaag atttagagct tgggagagag tttaaaatca ataatgatag tatatttaaa
    47161 tttgttgatt taatgaatat catggtagag tctatttctg attcttgcat gataaatata
    47221 gatattactg atttaaaaga agctattgta ggagataaag gaattaagta ttcttttgaa
    47281 gagtttgaag atacaaagtc atatagcgag atagctgaca ttttatttga caggatggaa
    47341 tatattggtg aggaatttat aagtaagaaa ggaattgtat ttgttgaagg aagtccagaa
    47401 ttttctataa tggaattgaa tgatttaata agtaatattc agagcaaggt agaagaaagc
    47461 tatgaagtaa tattttcttt atatataaag gaaaatttaa atggaaatat tagagtaggc
    47521 ttattgtata attagtatat tttagatatt aaggagagtg tatatgtctg aaaatataag
    47581 aggtacagag tattggttaa tggaagaatt tttttatcag gaaacagaca caccacagat
    47641 ttttatagaa gaaagcataa ttgcacttgg atttgatata aaaataaatt taaaaaaagt
    47701 attcagtatg gggaaaaaat cagaaaagta tattaatgag aattgtaatg ataaagattt
    47761 tataaaaaag tttatgtcga ttaaaaaagg agattatttt ttatataaag catatcaaaa
    47821 tatagaagaa aaagttaaat gtaatgtgtc tattggcata gttgaagaag attttgaaaa
    47881 tggatatgaa ttaagtcata ttttagggca tacactacca gtaaaatgga tgcataattt
    47941 tgatacagtt tcaaattgta aagtatatac aagtgaattt tataaattaa ataataatga
    48001 tattagttca tatttagaaa ttattaagtc acaagataag aaattattga gaaaaagaat
    48061 agaagaaagt gaaaataata aatggtattt aaaaaactat tattataaaa atgtagataa
    48121 gtgtgtagat gatgaagaat tatttattca gcccattaat ctagaacaat tagaaagcct
    48181 aaaaaatata aagacagatg attatatttt attgtataat agcgagaaag taatttgtga
    48241 aaatgaccat acaatgaaga gtctatttgg cgtatgtcaa gttatggaag ggttcgataa
    48301 agagaaagta agtgctttgg atggtggata tttttttcct gttagatgga tagagtatgg
    48361 aaaggagaat atagacggaa atgcatgggt tatatttgaa aataatagta tagttgaaaa
    48421 gtatgtaaaa agatttacta ataaaatgcc attaaatact atactttatg gaccaccagg
    48481 aactggtaaa acatacaata caaaacagat ggtttacaat ctagtaagtg aaaccagtct
    48541 aagaaacaaa tactatacag gttacttaga ttataaaaac aatgtagaat tttgtacatt
    48601 tcatcaatca tatggatatg aggaatttat agagggtctt aagtctgatg gtgaaggcaa
    48661 ttttaagcca gaagatggga tattaaagga tatatctata gaagcatgtt ataatgcatt
    48721 gaaatttgaa aaaaagatga gctttgagtt ggaaaaagat agcttgactt tagaaactat
    48781 aaaagacagg aaaaagaaat tagtattaga aaatatagaa tatagtgaga gttttaattt
    48841 tgaagaatca gaaaactatg ttttaataat agatgaaatt aatagaggga atgtatctaa
    48901 aatatttggt gagctaataa cattattgga agatgataaa agacttacta aatcaaatca
    48961 aactattgtc aaactaccat attcaaagga aaaattttct ctacctccaa atttgtatat
    49021 agttggaact atgaacacat cagataaatc aatagcactt ttagatatag ctttaagaag
    49081 aaggtttaat tttgaagaaa ttatgccaga ttatgattta ttgtctattg tagatggtat
    49141 agatattaga aaaatgctat atacaatcaa taaaaggata gagtttttat atgatagaga
    49201 ccatgttatt ggacaagctt atctacttgc tgtagaaaat attaatgata tagtagtagt
    49261 atttagaagt aaaataatac cacttcttca agagtatttt tattatgatt cagaaaaagt
    49321 aggtttgatt ttaggaggaa ttggaagaaa tgaaaaagat aaatacattg tttataaaga
    49381 aaaacttata gcttctgagt tatttaaaaa taataatgcc tcaataatgg agagtaaagt
    49441 taactattgt ataaaacaaa acatatctag tgaggagcta aaaaatatat atgagtaaaa
    49501 atatatatgt taaggaaacc tatgaatgga taagggtagg taatggtgaa aatgagctta
    49561 cagaaattga atatgaaaaa ttgcttaaat atctagagaa caataatgat gtattaaaaa
    49621 gtaatataat agatattaaa tacaaaaaaa ttagatttat aaactatgta ggcatcatat
    49681 gttttgaaaa tgtaatactt gaaatacttc ctaaattgtc attaagtgat aatcttgtaa
    49741 aagatagaga gatactatta cagatgcttt ctatatgtaa taaaattcca attacaatga
    49801 atgaaaaaat aagattgagt ttgaaaaatt ataatctctt aaattttttt gttatgtatt
    49861 tcattgagag tatgcaaaca cagatgaaaa aaggtattta ttttgaatat ataaataaaa
    49921 tagagaactt aaatgttatg aggggtaaaa tattattaag tacatatgca aaagaaaaag
    49981 gcatttctcc aatgaaaata agatgtgaat atgatgagtg tagtgaaaat aatttcttga
    50041 atcaagttct taaaaaagca tgtatatcta ttttatgtag aataaatgac aattcaattc
    50101 aaggcaagat taaaaaaatt ttaagctatt ttcaaaatgt agatttaatt tatatagata
    50161 gaaaaaaact gttgggttat aaattttata aaaacaatga tagatttaaa gattgttatt
    50221 tactagctag acttctactt ttaaatctat ctatggataa tagtcaaaat aatcaagagg
    50281 cattttctat attatttgaa ataaatactt tgtatgaaga atatatagga attttaatca
    50341 aaagtatatg ggacaattca tttagagaaa catatataca agataagagt aaatttcttt
    50401 tgaaaaatga acaaacaggt aagaaaaact ttaatttaag accggatata gttttatatg
    50461 acttaaaaaa tgaatatgaa attataattg acactaaatg gaaagctatt gaagtagatt
    50521 caaatgtttt ttataggtca agtgatatat accagatgta tgcatatata acagcatatg
    50581 aaaatgcaaa aagatgtata ttattatatc cttgtattca aaaagataag aattatagtt
    50641 cctggaaatt atcagaatca tttaagggta agtttataga agcaaaaact gtgaggttag
    50701 atgatataaa aaacacaaaa aatgatttaa aaaagata
//
LOCUS       DAMJWO010000018        48843 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.019, whole genome shotgun sequence.
ACCESSION   DAMJWO010000018 DAMJWO010000000
VERSION     DAMJWO010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48843
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.019"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            138..1355
                     /locus_tag="PC366_001113"
     CDS             138..1355
                     /locus_tag="PC366_001113"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HDF2576649.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDKYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            1450..1830
                     /locus_tag="PC366_001114"
     CDS             1450..1830
                     /locus_tag="PC366_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDF2576650.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            2114..2596
                     /locus_tag="PC366_001115"
     CDS             2114..2596
                     /locus_tag="PC366_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2576651.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNSINIEKVNDSVFSKKLMGDGVAII
                     PNSNVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVNLQGEGFKNEVSQGD
                     TVKKGSPIISFEREKINSQGIDCTTIIIVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            2617..3432
                     /locus_tag="PC366_001116"
     CDS             2617..3432
                     /locus_tag="PC366_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2576652.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            3483..5033
                     /locus_tag="PC366_001117"
     CDS             3483..5033
                     /locus_tag="PC366_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2576653.1"
                     /translation="MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     LPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGCIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPLLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSIIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEAY"
     gene            5130..6482
                     /locus_tag="PC366_001118"
     CDS             5130..6482
                     /locus_tag="PC366_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF2576654.1"
                     /translation="MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKERQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAESLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKVFYAGSHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            6613..7371
                     /locus_tag="PC366_001119"
     CDS             6613..7371
                     /locus_tag="PC366_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2576655.1"
                     /translation="MNIINKIFWQEDRIGMITNNLEADTHSHCMLQLFLGIEDSIEIT
                     VNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDND
                     GLEKLRQQGTFLIYNSSKEQYLRFMEMLNNYLNIPITLKHYDDRITELLNLLRTCNCD
                     NHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRELLSGKNVTEASMT
                     AGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY"
     gene            7418..8137
                     /locus_tag="PC366_001120"
     CDS             7418..8137
                     /locus_tag="PC366_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HDF2576656.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKNWLELDDFHKIKSIYEFV
                     QNDILFGYNASDMLSATQVLNDGMGQCNTKATLLMALLRAVNIPCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFFNHGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(8261..9661)
                     /locus_tag="PC366_001121"
     CDS             complement(8261..9661)
                     /locus_tag="PC366_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDF2576657.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADIGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLIARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLFLSPIAILDVILSFILLRNVGETQKLKLDIPSIVLSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPILIGIMSLILFTLRQLKSKEPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPIAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLIHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINNTLRQISGAIGSAILITIMTSATKKAHMSSNMLSNIHGIDVAFSIAATLAFTG
                     LIVSICFIKRHQIIRS"
     gene            complement(9665..10573)
                     /locus_tag="PC366_001122"
     CDS             complement(9665..10573)
                     /locus_tag="PC366_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2576658.1"
                     /translation="MKGDNKVTEKQRLIINIAQKIFDQKGFQNTSISDVVKECKMSKA
                     TFYKHFETKESFICEIINYYDEKFLEIIHSINENNDIPSSEKLNRKIIAVWKNIFSRT
                     TINTYIRENFSEEQRKATSKLQTKSRANLLNEYKLSLFDNYGDKIEKIIFDLVFLLDA
                     LIHQFIYIIHVQKREINVYFIAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEVYF
                     SLHNKSLFFKTIQDIEELIKTDTSLLENPKLLEAIKKLYVEGKNQQYDSLIMDAMIAY
                     LEKEDTLRPKVLLLNSIKNQLKKETL"
     gene            10834..11481
                     /locus_tag="PC366_001123"
     CDS             10834..11481
                     /locus_tag="PC366_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2576659.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARDAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGDDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKENITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            11806..14445
                     /locus_tag="PC366_001124"
     CDS             11806..14445
                     /locus_tag="PC366_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDF2576660.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQSLKVVE
                     GMLTGESEPVLKHTEKISEDVSLGDQKNMVFSGAVVVYGRGSFVVTGTGMDTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMAGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEEDFIPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     EGDLALTGKELDALSEEQLYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSIVFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLKAVAIRGCIIGVVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(14503..15606)
                     /locus_tag="PC366_001125"
     CDS             complement(14503..15606)
                     /locus_tag="PC366_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="HDF2576661.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSSK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFIALDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIPLSSIENIVKEAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVSPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQIIDNIE"
     gene            15967..16788
                     /locus_tag="PC366_001126"
     CDS             15967..16788
                     /locus_tag="PC366_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2576662.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    16867..17078
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17165..18481
                     /gene="argH"
                     /locus_tag="PC366_001127"
     CDS             17165..18481
                     /gene="argH"
                     /locus_tag="PC366_001127"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HDF2576663.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCVLYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLVLDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVGLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELHKFSDAFKEDIYDFIDYESILNKGIKKNLK"
     gene            18730..19068
                     /locus_tag="PC366_001128"
     CDS             18730..19068
                     /locus_tag="PC366_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HDF2576664.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGRP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(19195..20484)
                     /locus_tag="PC366_001129"
     CDS             complement(19195..20484)
                     /locus_tag="PC366_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF2576665.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPAIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKDLPQIDGSSMYLKNGE
                     SFTVKQLLDALLVHSANDAAFVLARYVGGGNVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELIYEPKNSYRIFLEKDESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNVYNNGKLENSIDLIAKNNLDSSLPFFTGNNILMT
                     FVKIIAGILVLLVLFIIASNIKKKKRKKARSKKNMKK"
     gene            20564..21268
                     /locus_tag="PC366_001130"
     CDS             20564..21268
                     /locus_tag="PC366_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="HDF2576666.1"
                     /translation="MKKKVKFISFFVLFILIISSIIVYKSLIFKDDIYVVSKKNLPNE
                     KTHVVENEIKGEDNNHNKVTKDIDKNFQNNKITIYISGAVNRPGIVTIESDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEATSVTSNDDSNKPNQKNESRGEPK
                     NKSNKNISNESKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            21360..22406
                     /gene="selD"
                     /locus_tag="PC366_001131"
     CDS             21360..22406
                     /gene="selD"
                     /locus_tag="PC366_001131"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:21408..21410,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HDF2576667.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDNPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHTVDDKEPKYGLSVSGIVSPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFEK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEVVGNIEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            22424..23836
                     /locus_tag="PC366_001132"
     CDS             22424..23836
                     /locus_tag="PC366_001132"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HDF2576668.1"
                     /translation="MIVLSKRELFAMLPSVDEVLSDNRIVEIINEYPRSLVLESVREV
                     IDLKRQFILRLKEDASNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLG
                     RSLLSEDIKDELWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNA
                     AAVLLVLSTMAKGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYK
                     EAITEDTNVLMKVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKY
                     GLSYEPTVLDSIRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDK
                     LTICALEATLRMYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINI
                     EDGFSQVGGGSMPLETISTKVISITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDV
                     RTIFDDEFDVIVAELRKAFN"
     gene            23950..25833
                     /gene="selB"
                     /locus_tag="PC366_001133"
     CDS             23950..25833
                     /gene="selB"
                     /locus_tag="PC366_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HDF2576669.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNENSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIESGESGYVQLRLEESIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKRALEALISEDKVFIIGNMYMHINQYNKLKENTIKLLS
                     EYHKKYRLRKGILKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNDKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNILINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            25938..28676
                     /locus_tag="PC366_001134"
     CDS             25938..28676
                     /locus_tag="PC366_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HDF2576670.1"
                     /translation="MKNIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDIEKYETLL
                     HAIYTIFLVATGVIIFNTTKFKVDSFSTFLGLIFIATGVLECIYLFNSLGIKTKSIME
                     INITISAITDLFPILGVYLSFKFVKDNKQIYSSIILFIATATLTITSLFIISGICDYL
                     GNGKSQYALGVIISIFIIIISIISGIELNSSSNKGKWEYDEKKIFNRIIVIIILSRVP
                     NLLHIVIDNRNVERILSQIIINVALYYLYNYIVSKNIKKTALELHDTNEELTKKTESL
                     KEKNKKLIYETEKIEELKGILMKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESIHYVFVHEKNAEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSKDFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTNKTIIVIRDTTSRK
                     ISQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEYELINSYDDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRNEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTDLEEINVYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVVSEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(28795..29739)
                     /gene="manA"
                     /locus_tag="PC366_001135"
     CDS             complement(28795..29739)
                     /gene="manA"
                     /locus_tag="PC366_001135"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HDF2576671.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGKYKGKKLSELWNKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVNMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNSGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFKCTTFVSNEFFSVYKLDVFGKCNFTHNTPFSLYSVLDGNGK
                     LIHNSVEYNLKKGMHFILPNDFGDFSFEGNLEIICSHI"
     gene            29912..31273
                     /locus_tag="PC366_001136"
     CDS             29912..31273
                     /locus_tag="PC366_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2576672.1"
                     /translation="MELFKAESKKYEKEFLKLLEQWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLISNIDDKSLYISGGIEFNTIPDKVYI
                     KNVEKLGKDNICFDINNISINYDNGNYIVYGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSIVPTIINIVDGKLEVVLSVRYPEIL
                     TIEDIIKKFNLYMEQNNINKFELIGENLKQANYIDRNSKLVRSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHSANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            31361..33250
                     /locus_tag="PC366_001137"
     CDS             31361..33250
                     /locus_tag="PC366_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2576673.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIASSRGIGYKLSGSKNNIARAVKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIYCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIENLMKEISDKIGFKLIEDEVIYISNYSGV
                     IAYKGTQGRKNTSEIEERISSVISSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFSIKASTK
                     EEVIISLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            33265..33720
                     /locus_tag="PC366_001138"
     CDS             33265..33720
                     /locus_tag="PC366_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2576674.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKDLNLAEDESLVY
                     EGLMAREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKEFKDSLLKSDNVEEISNLINEALGL"
     gene            33779..34096
                     /locus_tag="PC366_001139"
     CDS             33779..34096
                     /locus_tag="PC366_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF2576675.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            34121..35383
                     /locus_tag="PC366_001140"
     CDS             34121..35383
                     /locus_tag="PC366_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF2576676.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFIDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKRLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAIWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            35488..36552
                     /locus_tag="PC366_001141"
     CDS             35488..36552
                     /locus_tag="PC366_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2576677.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     ESQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIVDFIKIGMTE
                     KQVENEIVRIIKDLGGQKESFDTIVASGLRGALPHGKASEKIIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YANNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITQDGCMRLTTSTKDLIVVS"
     gene            36606..37784
                     /locus_tag="PC366_001142"
     CDS             36606..37784
                     /locus_tag="PC366_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HDF2576678.1"
                     /translation="MYNFDDKPDRVSEKCRKWDLNIIRDKFGDIREDFVPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVNVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEVQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTRVATICKENNVILVADEVHAEHIHYGKFNS
                     ILKIGKELLENVILLTSPNKGFNLGGLKTSYSIVINKNIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLSGVNEYIKSNYELLETWVNKYNKIKLMKMESSYLAWMDISGL
                     GISASEFTDKLAIDTGVLLEDGSHFVKDGEKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            complement(37975..39033)
                     /locus_tag="PC366_001143"
     CDS             complement(37975..39033)
                     /locus_tag="PC366_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HDF2576679.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNE
                     VTIFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDE
                     KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLEDGKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKDGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMDLINEIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKSFSIEKLNKQ"
     gene            39100..39471
                     /locus_tag="PC366_001144"
     CDS             39100..39471
                     /locus_tag="PC366_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HDF2576680.1"
                     /translation="MKKKDILLILGILVVIIACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIENRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            39508..40182
                     /locus_tag="PC366_001145"
     CDS             39508..40182
                     /locus_tag="PC366_001145"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDF2576681.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            40431..41270
                     /locus_tag="PC366_001146"
     CDS             40431..41270
                     /locus_tag="PC366_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HDF2576682.1"
                     /translation="MNFKKLSNAKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDANDIVTLDENTKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            41513..41609
                     /locus_tag="PC366_001147"
     tRNA            41513..41609
                     /locus_tag="PC366_001147"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41547..41549,aa:Sec,seq:tca)
     gene            41760..42467
                     /locus_tag="PC366_001148"
     CDS             41760..42467
                     /locus_tag="PC366_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HDF2576683.1"
                     /translation="MENNFTTRTSFLVGDDGIEKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NKDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIVNELLGQ"
     gene            complement(42609..43445)
                     /locus_tag="PC366_001149"
     CDS             complement(42609..43445)
                     /locus_tag="PC366_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2576684.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHIIDVGQGDSILVQTPT
                     NKNILIDGGDEDSENIIISYLRQKRIKTIDIIIATHPDSDHIGSLDNVIKKFNVNSIY
                     MPEQSTDSEAYQNLINSCTDKNLSIQHLYKNDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNDNSFLFMGDAEEENEKEILHSFKLNNINFIKIGHHGSNSSSSLEFIKKIS
                     PDIAAISCGYKNQYGHPHREVINNLKQNHVSIYRTDRIGDIVFYSDGEIIFTKYNYEI
                     DT"
     gene            43633..44538
                     /locus_tag="PC366_001150"
     CDS             43633..44538
                     /locus_tag="PC366_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
                     /protein_id="HDF2576685.1"
                     /translation="MFFKDIELNSKKELDPYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPGRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYEAKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            44547..45731
                     /locus_tag="PC366_001151"
     CDS             44547..45731
                     /locus_tag="PC366_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2576686.1"
                     /translation="MEIRYAKEEEIESIKEIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNSKVYNTSYVVGVSTLPEGRGAGYMNKVMKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     RIDRTFLNEVNGNVLKDEHYYENLFKEIQSEDGFLYIHEGNEKDGYIVYFLQEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPTIDKIRFILDNPKDSDIKIKPFMMG
                     RVINVKKFIEDIDIEKDINSSFNLLIEDKFIDENNGLFKISIQNKKVSVEQLDKKGAE
                     KPQEDFDIKLDINTLTQLSFSYIDVNEAIFLNDIKDVSEETLETLNCIFSKKNTYINE
                     YI"
     gene            45846..47147
                     /locus_tag="PC366_001152"
     CDS             45846..47147
                     /locus_tag="PC366_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HDF2576687.1"
                     /translation="MGVIIIQIRRPLLIILMFVVAISFIITNNTKNDEELNDKIITIQ
                     GVVKGKIEKKRYNQYKVGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGR
                     YIKSTGYKGIVYINNYKIIDKNKLYSLIGEIKFYISKTYRYLYKKNSDFINSILLAEV
                     ENLTEEQKEIFTRTGTSHVISISGLHTGILCVIISFLLRGINKLYKLLILSIFITLYC
                     IMVGASPSIIRSIAFVMIFYLSIFIDRKKDGISALSLIGIILIMNNPYVIYNVSFQLS
                     FLATLSILIFYNKINSIIKLSMVSLTISSNILTLPIIYYTFKGIPLLSIIGNLIIVPF
                     VGVIMYLSIASLIVFKVSVVIAKIISFFNSTLIESIFFLLEKISNLSFAYINIESPKF
                     YIVVIYYIGVFFYIFYIEGKEIKEQENELQGYYKECKREKL"
     gene            47101..48144
                     /gene="holA"
                     /locus_tag="PC366_001153"
     CDS             47101..48144
                     /gene="holA"
                     /locus_tag="PC366_001153"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HDF2576688.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGNNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(48331..48597)
                     /gene="rpsT"
                     /locus_tag="PC366_001154"
     CDS             complement(48331..48597)
                     /gene="rpsT"
                     /locus_tag="PC366_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HDF2576689.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
BASE COUNT        19157 a         5274 c         8345 g        16067 t
ORIGIN      
        1 aattgttgta tttttaggtt ttttgtgatt aattaaaaaa ttataaaaat cgtttacatg
       61 ttgattttta aaaaaaaaag atatagaatt atatagaaag taataaacaa aaattggatt
      121 tacgggagtg gaatgaaatg atgaatgtta ccttaacaga tgtgaaagag gctagagaga
      181 ccattaagaa catagtaaaa agaactgact tacttgaaag tgttaaactt agcgaaaaaa
      241 caggagcaaa tgtgttctat aaatgtgaga atcttcaaaa aacaggttct tttaaattaa
      301 gaggagcttg taacaaaata gcgagtttaa cagatgaaga aaaggcaaat ggagttatag
      361 cttcaagtgc agggaatcat gctcaaggag ttgcattggg agcaaaaatg actggtataa
      421 aatctacaat agtaatgcca gcaactgcgc ctttagcaaa agttagtgca actaaaggtt
      481 atggagcaga agtagtttta aatggtgcgg tttatgatga tgcatatgca aaagctgttg
      541 aaatacaaaa agaaacagga gcaactttct tacatccatt caatgataag tatgttatag
      601 caggacaagg aactatatct cttgaaattt tcgaacaatt agacaataaa gttgatacta
      661 tactatgccc agttggtgga ggaggaatca tctctggtgt tgctgttgca gcaaaagcat
      721 taaatcctaa tgtaaaaata gtcggtgttc aaactgcaaa tataccttca atgaaagagt
      781 caataaaaaa tggaaaagta acaacagcat ttaatgatac tacaatagct gatggtatag
      841 ctgttaaaac tccaggagat ttaacttttg aaataataaa tgaattggtt gatgaaatag
      901 tagtggttga agagacagaa attgcagaat caatattatt tatgatggaa agtcaaaaaa
      961 tagtttcaga aggtgctggt gctgtatgta cagctgctat attaagtggt aagtatgtac
     1021 cagcaaaaga tgaaaatgta gtttgtataa tatctggtgg taatatagac ataaatacgt
     1081 tatatagaat aataggtgtt gctttagcta aagaaggaag aagatattca tttagtacaa
     1141 ttatggaaga taagccagga aactttgctg agttaactag aataataagt gagaatggtg
     1201 gaaacatttt aagtgctaat caaggtaaat tatcagcagg ggaagctcta ggaaaacaaa
     1261 gtgcggaatt tatattagag acaatagatt atgaccatat agctagaata aagaaagcta
     1321 tagaagaaaa aggttttaaa attatagaat tataataaaa agtgtatata atatacaaga
     1381 aaaatagtat aatagtgtat gaagatacat tttatgtgta ttagattaac gaattaggag
     1441 gattttaaaa tgaaacatga agtaatacat actaatgatg caccagcagc tttaggacca
     1501 tattctcaag ctataaaagc tggaaactta ttatttgtat ctggacaagt tcctcttgta
     1561 ccagagacta tggaagtagt tgaaggagat gtacaagctc aaactgctca atctttaaaa
     1621 aatcttaaag ctatattagc tgaaagtgga gctgattttt caaatgtagt taagactaca
     1681 gtatttataa aagatatgaa tgaatttggg gctataaacg aagtttatgc tgaatatttt
     1741 ggagaaaata aaccagcaag agcttgtgta gaagttgcta gattaccaaa agacgttaaa
     1801 gttgaaatag aagtaatagc tgtattataa aaatacaata tttttaattt gaaaaggctg
     1861 aaaaactata ttctagtgat tcagtctttt tataaaaaaa taaatcacaa taaagaacat
     1921 gataaatatt gtcgaattaa aaaataaaat taaaataaat attgcaatat ttttgagaag
     1981 gttttataat gagtatataa tttgaaacgt gtaactatta aattaggcat gagttcttgg
     2041 atatttttat cctgaggatt catgcctttt ttgtattgaa attcaaaaat ctatttaata
     2101 aggaggaagt attgtgttaa attttttcaa gaaaaataaa agctataagt tacatgcagt
     2161 agtgagtggt aacagcatta atattgagaa agtaaacgat tctgtgtttt caaaaaagtt
     2221 aatgggagat ggagttgcaa ttattcctaa tagtaatgtt gttgtagccc cttgtaatgg
     2281 taaagtaact gtgcttacag aatcaaagca tgcctttggt atggtctcag atgagggtgt
     2341 tgaaatatta gtccacatag gaattgatac agttaattta cagggtgagg ggtttaaaaa
     2401 tgaagtgtct caaggagata ctgttaaaaa aggtagtcca ataataagtt ttgaaagaga
     2461 aaaaataaat tctcagggaa ttgattgtac aacaataata attgtattaa atcatagcga
     2521 attttcagaa ataaattgca tggtagaaaa tgaagttgtt gcagggcaag atactgttat
     2581 tgaaattatg aaataatagg aagggattaa ttcaatatga gagtagtaaa aatctttaat
     2641 aataatgcat tatctacagt aactaatgat aggaaagaag ctattttact aggtcttggt
     2701 ataggtttta ataaacgtcc aggagataaa gttaatgaag ataaaataga aaagatttat
     2761 tatgttcaag accacatgca aacaaaattt ttagaattat taaaaaatgt tagtccagaa
     2821 gtgatggatg cttcacaaca aattataagt cttataccag gaaatgaggg aaaatttaat
     2881 aataaaggga tattatcttt agtggaacat attagttttg caatagatag aatgaaaaat
     2941 aatgtttttt tacctaattt aatgcttttg gatataaaga tgatgtattc aaaagagttt
     3001 gaattaggag taaaagcttt agaaattata tatagagtat gtcatatcca tttgcctgaa
     3061 gatgaagcag gttacatagc tttacatttt gtcaatttac aatcaaatga taatttggca
     3121 tatgatactt taaaatttgt aaaaggtagt attgatttga ttaaagaatg ttatggatta
     3181 gaattagacg aatcgagttt aagtacatta cgttttagaa ctcatcttaa atttcttgct
     3241 caaagaattt ttaagaatga aatttgtcag gatgataaaa tgattgaaat gtatgattat
     3301 ttaattaaca atcatcctaa aaataaagaa tatttagaaa agttaaatgt atatattgaa
     3361 aaggagttta ggtataaatt agataaacct gaaaaaattt atctactact acacctaaca
     3421 aaaatcttat aagaatgaga tgaattagta atagaaatat ataattttag ggggggataa
     3481 gattgaaaga aaaactactt ggaggactgg aaacatttgc aaaggcaatg gttcagccat
     3541 taatgtattt atcgagtgca ggaatattaa tggtggtagg tgtactactt acaaatgata
     3601 tgttattagg agtacttcca ttttttaaat gggagccaat tcaaatattt ggaagcctaa
     3661 tttataactg tataatggct attattaata atcttgctgt tatatttgct ataggtattc
     3721 ctgctgcact agcaaaaaaa gagaagcaca aagcagcgtt aataggattt atgagttata
     3781 taatatacct tacagcttcc aacactatgt taacatcact aggtcaacta gcaaaagaaa
     3841 gcaagatgct tggactgata gggactggac aagctactat tttaggtatt caagttgtag
     3901 atacaagtgt atttggtgga attattttag ggtgtatagc tggatatgta tttaatcgta
     3961 caagcaacaa aacatttaaa ggagctttac agatatactc gggagcaaat tttagtttta
     4021 tatgcatgtt ctttgtatcc attttaattg gagttgtgag taactttata tggccattag
     4081 ctcaacaagg aatagcttct cttgcaaatg tcatcaaaga tacaggtaca tttggtttat
     4141 tcttatatgg ttttttagag agaatattag taccaactgg acttcatcat ttaatctata
     4201 caccatttca gttttctgat ttaggaggag tgcttaaagt tggtgcagat acagtttcag
     4261 gagcctatgc tatagttatg acagaaatga atttaccagt tgagcgtttc tcagatagta
     4321 tatactacat ggcaactgga tttacaaaga tgtttggtta tataggtata ggagctgcct
     4381 ttatttatac tgcatataag caaaataaga agaaagttaa ggcaacgatt attccactaa
     4441 taattacggc agtattagcc tctgtaacag aaccattaga ctttatgttt gtattctgtg
     4501 caccactttt attctttgta catgcagtta tagctggtct ttttatagct ttattaaaaa
     4561 tatttgatgt tactgcatta tgtggaggga acttattagt atcaattata atgaatacta
     4621 cagtaggtgt agaaaaaaca cactggccag taatgatgat attaggactt gcacaaatta
     4681 ttgtatattt tgtagtattt agttttttaa ttaagaaatt taattataaa actccaggtc
     4741 gtgaagatga gagtacagct acaggcgaag aacaatcaaa acaacttaat ttagatgcag
     4801 gtatagaaaa tataattgat gggttaggcg gaaaagaaaa tattaataca gtagaaaatt
     4861 gcatcactag attacgtgtt aatgtaaaag atgaaagtaa gattaatgaa gatataatta
     4921 atttaacgcc aaatagcggg attgtaagga aaggaaaaga tatacaaata atttttggac
     4981 ttcatgtgca tgaggtaaga cgtgcagtag aagatttttt agaagcttat taaagatata
     5041 tatttatata gcaagggtaa ataacagctt taagtgctgt ttactattta ttaaagatac
     5101 atataattta tagaggagga ataattatta tgattattac tattgttggt ggaggaagca
     5161 catttactcc aggtattgtt aagtcaattg cgttaagaga aaaagagtta gagcttgagg
     5221 aaattcgctt atttgacatt gataaagaac gccaagataa agtagctgta gttgtcaact
     5281 ggatactaaa agaagatgtt aaaacagatg ttaaactaac tgtaactaat tgtgaaaaag
     5341 aagcgtatac agatgctaca tttatatttg cacaaatgcg tgttggtaaa tatgaaatgc
     5401 gtgagcagga tgaaaaaatt ccattgaaat atggttgtgt aggtcaagaa acttgtggtt
     5461 gtggagggat ggcatacgga ctgcgtacaa tacaaccaat gataaaggtt attgatgatg
     5521 tagagaaata tgctaaaaaa gattattgga tattaaatta ctctaatcct gctgcaatcg
     5581 tttctgaagc ttgtcgtaag ttaagaccaa atgcaaggat tataaatatc tgtgatatgc
     5641 caatagctat tatagatatg atagcggagt cattaaatat caatgacgtt cataatatac
     5701 gctatgatta ttttggtcta aatcattttg gctggtttac ttcaatagat tataaacata
     5761 gagacttaat ggaagagatt aaggaataca taaaagaaaa taaaatatta ttaccaaaat
     5821 cttatataga aaacttaaat aaaagtcgta gtacaggaaa tcgccatgct gtaagtagct
     5881 ggatacatgt ttgggaatct gtttatacaa tgttagaaag cttcccaaaa tatctgccaa
     5941 acacttattt aacatactat cttttaagta aagaaacagt ggaacattca aacataaatc
     6001 gtactcgtgc aaatgaggtt atggaaagcc gtgaaaaaga cttatttgaa ggtgtgagac
     6061 attacttaga aactggagaa atttctgaaa aagtatttta tgcaggttca catggagatt
     6121 ggattagtga tttggcagtt tcaattaaaa atgatacacg tagtcgtttt ttagttataa
     6181 ctgaaaatcg tggagctata ccaaacatgc catatgatgc aatggtagaa attccagcat
     6241 atattggtaa agatggtcca gaagttattg ctcgaggtcc aatacctcta ttccaacaag
     6301 gattaatgat gcaacaactt aacagtgaaa aattgatagt agaagcttat atagaaaata
     6361 gttatgaaaa agctttacaa gcattcacat taaataaaac tattccaagt atgaatgttg
     6421 ctaaagaaat tttggatgaa atgatagaag ttaataagga atactggcca gaattaagat
     6481 agtaggataa aagaaagggt ttttatttaa taattagata tgttttcaga gtcttttatc
     6541 aaaatgtatt cacaaacata tggcaatata ttaaaataaa gagtgatatt tttagaagaa
     6601 tggggtgatg caatgaacat tataaataaa attttttggc aagaagatag gattggcatg
     6661 attacaaata atttagaggc agatacacat agccactgca tgttacaact gttcttaggg
     6721 atagaagaca gcattgaaat aacagtcaat gaaaaattag ttaaatgtaa ttgtatcata
     6781 gtagataaaa atatctctca ttcattttca gcaagaaaaa aagtttatta ctctgctatt
     6841 attgaaccta catctatata tgcagaacag cttacctcaa aaatgaatga ttttggctac
     6901 tggatatgtg acaatgatgg attagagaaa ttacgtcaac aaggaacttt tttgatatat
     6961 aactctagta aagaacaata tttaagattt atggaaatgc ttaataacta tttgaatata
     7021 cctataactc tcaaacatta tgatgacaga attactgaat tgctcaattt attacgtact
     7081 tgtaattgtg ataatcatac tatttcaagt tttgcagata aagtgtccct atcagcaagt
     7141 agattatcac atctgtttaa agaacaaata gggatacctt taaaaagcta tatcttattt
     7201 catcaaatgg agtgtgcttt tagagaatta ctttctggga aaaatgttac cgaagcttct
     7261 atgactgctg gattcgatac tccatcacac tttgcaggga cagttaagcg aatgatggga
     7321 atgcctgttt ctttatcttt gaaagatagc gaatttttga aagtatatta aatattctcg
     7381 ttatataatg aagttgtact aagaaagggg ctttgttatg aataaagaat atttagagga
     7441 aacaaaaatg ttaaattata atgaaccaca acttaagctt ttggtatcat caaagaattg
     7501 gttggaatta gatgattttc ataaaataaa atctatttat gagtttgtac agaatgatat
     7561 tttatttgga tataatgctt ctgatatgtt aagcgcaaca caggtattaa atgatggtat
     7621 gggacaatgc aatacaaaag ctactctttt aatggcatta ttacgtgcag tgaatatccc
     7681 ttgtaggctt catgcttttg atgtaacaaa agattttcaa cgaggtgcta catccaaatt
     7741 gatttcacta ttagcaccaa aatatattct tcatacttgg gtagaggtat tttatcaaga
     7801 taggtggatt gctctggagg gtgtcataac tgataaaaaa tatttagaag caattcagaa
     7861 gaagtttttt aatcatggtg gaacgtttaa aaagtatgca atagctacaa atgatttgaa
     7921 aaatacatct attgattggg atggtaaaga tacttttatc caaaaagaag ctatcgtgta
     7981 tgattatggt atttttccat caccagatgt atttttttct actcattcac aacatatgtc
     8041 aaaattaaaa aatttcatat atgtacatct tatcagaaaa ataatgacaa aaaatgtatg
     8101 taaggctaga aacaattata ttgataaaaa cgaatgagtg tttaagaggt aactatatag
     8161 gaaatatata gaataattaa aactgtactg gttaaaatga ataaaaagga gttatcatag
     8221 agcaaactta aattgttcat aggataactc cttttctgta ttaacttcta ataatttgat
     8281 gtctttttat aaaacatata gatacaatta aaccagtaaa tgcaagagta gctgctattg
     8341 aaaatgcaac atctattcca tgaatgttag acagcatgtt tgaactcata tgagctttct
     8401 tagtagcact tgtcattata gtaataagta tagcagaacc tatagctcca gatatctgac
     8461 ggagtgtgtt attaattgct gtggcatgag atataagttc tctatctaat gttttaattc
     8521 cccatgtagt taatggcatt aaaaccattg aaataccaat catacgaata caatacatca
     8581 atgacacatg aattaaagat gtatctctgc ctaaaaaagc gaaggataaa gttcctaaaa
     8641 acaaacatcc tgttcctaat attgatagag catgaggtcc atatttatct aaatgacgtc
     8701 ctgcaattgg attgagtaca accatcaata tagcaccagg taacattaat gaacctgaag
     8761 ataatgcaga aaatcctctt acagattgaa cgtacagagg aatcattaat gtagcagaca
     8821 tcattgaggc atatacaatc ataattaata ttgtagaaat aagaaatggt ttatttttaa
     8881 aaaccctcaa ttctaaaaaa ggttctttag attttaattg acgcaatgta aataaaatta
     8941 atgacataat tcctattaat attggtaaat atgtggcaat attagtccac ccataattac
     9001 cttgattagt aaatccaatt aataaaccac caaaacctag agatgatagt actattgaag
     9061 gtatatctaa ctttagtttt tgagtttccc caacatttct taatagaata aatgatagta
     9121 taacatctaa tatagcaata ggggaaagaa acagaaataa actatgccaa ccaaatgaat
     9181 ctactaacca tcctgataaa gttggaccta ttgctggagc aaatcctact gtaataccaa
     9241 ctaaactcat agctgcacca cgtttttcct cagggcataa atagagtata ataacttgta
     9301 aaagtggcat tagagaacca gaacccattg cctgcaacac acgagcaatc aacatagttg
     9361 aaaaattatt agaaaaaagt gcaataatac atcctataga aaagatagac attgatgtaa
     9421 taaataactt tctagtacta aatcgattta ttaaataagc tgttgtgggt acaataatac
     9481 ctgcaataag tagataaatt gttgttaacc actgaccaat atcagcagta attttaaaat
     9541 ctgacattat attaggtaat gctgttgaca atagtgtttg actgagagaa cttataaaag
     9601 caccagtcat tacaattgct attattaaat ttcctttttt attgttactt tgggtttcca
     9661 taatttataa cgtctccttt tttaattgat ttttaatgct gttcaataaa agtacttttg
     9721 gtcttaaagt gtcttctttt tctaaatatg caatcattgc atccataatt aaagaatcat
     9781 attgttgatt ttttccctcg acgtataatt tttttattgc ttctagtaat ttaggatttt
     9841 caaggagaga agtatcagtt ttgattagtt cttctatatc ttgtatcgtt ttaaaaaata
     9901 gcgatttatt atgaagggaa aagtaaactt catcttcttg tttatgtaaa aacattgatt
     9961 tttcaattaa aggatttaga ttatccatat tttctacaac taaatctaga atttgtatag
    10021 taaatttggc aataaagtat acatttattt ctcttttttg tacatgaata atgtatataa
    10081 actgatgaat tagagcatcc aataagaaaa ctaaatcaaa tataattttt tctattttat
    10141 caccatagtt atcaaataag cttaatttgt attcattcaa taagttagct cgtgattttg
    10201 tttgcaattt acttgtagcc ttacgttgct cttcagaaaa attttctctt atataggtat
    10261 ttatggtagt tctagaaaaa atatttttcc atacagcaat tatctttctg tttaactttt
    10321 ctgatgatgg aatgtcatta ttttcgttta tggaatgtat aatttctaaa aacttttcat
    10381 cataataatt gattatttcg cagataaaac tttccttagt ttcaaaatgc ttgtaaaaag
    10441 tagctttaga cattttacac tcttttacaa catccgatat tgaagtattt tgaaaacctt
    10501 tttggtcaaa aattttttgt gcaatattta taatgagcct ttgtttttct gtcactttat
    10561 tatctccttt cacgcaaaaa cgtttagtac tatatagtac ctacaagttt taataaatat
    10621 attatacatc atttggaaaa aaaatcaata tatagactgt aatatgaaat ttttgaaaaa
    10681 tttgttgtta tttttagtcg tataaaaaag aaacttaaga gtttcttaag aattgtttaa
    10741 agaagttgca ataaattagt ggtatgatta tagtatgaaa gagaatgtct tgaaattttt
    10801 ctgtatcaaa ttccaattat ggaggtgtag tatatgaaaa agaaaatttg tgtagcaata
    10861 atttttgctc tatttatagt ttttgtagaa atgtttattg atagctctag cgaaggaagt
    10921 aaaattatga cagctgaatt aagtaaatac aggaaaggcg taaatgtatt atcaataaac
    10981 aatattatag tagcgaataa aaaatatagt ttgcccaaag attattctcc tcaggaaagc
    11041 agtgaagcga gagatgcttt ttataaaatg aataaagatg ctcaaaagtc aggattaaat
    11101 ttaaaagctt ttagtacata tagaagttat gaatatcaag atagattatt taaatcatat
    11161 gtaaaagaac atggagaaaa agaagcaaat agattttcag ctaaacctgg agagagtgag
    11221 catcaaactg gacttgcttt tgatattgga ggagatgacc agtcttgttg ggcaaataaa
    11281 aagttcaaca atacaaaaga agctaagtgg ttgtatgaaa atgcatataa atatggtttt
    11341 atacttagat atccagaagg taaagagaat ataacaggat atatgtatga atcttggcac
    11401 tatagatatg ttggaactga acatagcaaa aactttgcaa tgaataattt gactttagaa
    11461 gaatatttac atataaatta agagatggtt tgttaaaatt aggttaaaat aaaaaataac
    11521 ctagactatt agctgtgtaa agtgatataa tgtaaataca atttaagata actactcgaa
    11581 ggggagtagc ttacacgaaa gtggtaatta atcgtcaaga cagtagaaat actcggttaa
    11641 ttagcaaggg attccttgat agcaagacct tcaaaataag cattaggtat gtttgttttg
    11701 gggtcttttt ttattcaagg aatttttatt taaaaaaatt taaatttcaa gtatacataa
    11761 gagcccccaa acataaaata aatttattga agaggagggc aacaaatgtc ttacaaaagt
    11821 acttatcaag aagtaattaa aaatttagac tcaagtttat ctggtttgag taaagaaaga
    11881 gcagaagagt tgttggaaaa aaatggagct aatgaattaa aagaagcaga taaggttcct
    11941 acttataagc ttttcctaga aagttttaaa gacccattag taataattct attgatagct
    12001 gctttagtac aaatattttt aggtgaaaca gtggagtcta taataatttt tgcagttatt
    12061 attataaact ctgttctggg tgttgtacaa acaaaaaaag cagaaagttc attagaaagt
    12121 ttgaaaaatt tatctgcacc aaacgcaaag gtaataagag acaataaaaa aatgacaatt
    12181 ccagcaaaaa atctagtagt tggagatatt gtattcttag aagctggcga ttacatacca
    12241 gcagatggaa ggcttataga agcacaatct ctcaaggttg tagaagggat gttaactgga
    12301 gaatcagaac cagttttaaa gcatacagaa aaaataagtg aagatgtaag tttaggtgac
    12361 cagaaaaata tggtatttag tggtgctgta gttgtttatg gtagaggttc ttttgtagtg
    12421 actggaacag gtatggatac tgagatgggt aaaatagctg ggcttttaga aagtgctgaa
    12481 aataaactta caccattgca acaaaaaata gaggatttta gtaaaaaact tggtgtaggt
    12541 attgtaatac ttgctctttt aatatttata attcaagtag caagaaatta ctttatggct
    12601 ggaaatggag aaatgacaca aattatttta gattcattca tgttctctgt agcagtagca
    12661 gtagcagcta taccagaagc tctatcatca atagtcacta tagtattggc tgttggaaca
    12721 aatagtatgg caaaaaaaca agccataata agaaaattac cagcagtaga aactttaggt
    12781 tcaacaagtg taatatgtac tgataaaaca ggtactctta cacaaaataa aatgacagta
    12841 gttgattatt atatgtatgg aactaataat gatgagttag ataaagaaaa agtaaactat
    12901 tcttatcatg ctaaattatt gactatggtt tctacattgt gtaatgactc tcatataact
    12961 agtgatggta aagaagttgg tgacccaaca gaagtggctt taataaatta ttcaagtaaa
    13021 aatgatttag attatgataa attaagaagt aagtatatca gaataaatga aataccattt
    13081 gattcagaca gaaagcttat gtctactgta aatagtatat atggagatta tataatgttt
    13141 acaaaaggtg ctccagatat tgtgtttagt agatgtaaat atgctttgaa aaatggttca
    13201 aaagtagata taacagatga gataatagaa gaatataaac ataaaaatga agagttttca
    13261 aatagagcac ttagagtatt agcttttgca ataaaagatg tcccagaaga agattttata
    13321 ccttcaattg atgacgaaca tgacatgaca ttggttggaa taatggcaat gatagaccca
    13381 ccaagagaag aagtaatgga tgcagtaaaa gaggcaaaga gtgctggtat aaaaactgtt
    13441 atgataactg gtgaccataa aacaacagca gcagcaattg caaaagagat tggtataatg
    13501 gaagaaggag acttggctct tactggaaaa gagcttgatg ctttgagtga agaacaacta
    13561 tatgaaaaac tagaaaatat aagtgtatat gccagagtct cgccagaaaa taaaattcgt
    13621 atagtaaaag catggcaaca taagaataat ataacagcaa tgactggtga tggtgttaat
    13681 gatgcacctg cattaaaaca agcagatata ggaattggta tgggaagtgg tactgatgta
    13741 gcaaaagatg cttctgctat ggtattggtt gatgataact ttgcaagtat agtaaatgct
    13801 gttgaagttg gtagaacagt atacagtaat ataataaaat caattactta tctatttgca
    13861 ggaaacttag gagctatagt atccatagta tttgcagtgt ttgcaggttg gtcaaatcca
    13921 tttacagctt tacaactttt gtttataaac ttagtaaatg actctttacc agcaattgca
    13981 ttagggtttg aaaagtcaga aaaaaatata atgaataaac ctcctagaca cccggatgaa
    14041 agtatactag caggaggaac attgaaggca gttgctataa gaggttgtat aataggtgta
    14101 gttacaataa ttgcacaata tataggatta caagtatctc cagaacttgg agtagcaatg
    14161 gcattttcaa cattgatatt agctagaata atgcaaacat tacctgcacg ttctaataat
    14221 caaacagtaa taaaattagg ttttttcagc aataaatacg ttataggagc agttttagtc
    14281 tgtcttgggc tttactcttt aacactaata ccagtgctaa gaggaatatt ctctatacca
    14341 acaacgtttg gattgtacca gttggggatt tgcctagggt tagcattaat ttcatcaata
    14401 ttaatggaac ttaacaaatt aataaataga agtgaagtaa aataatcaaa aaattaaagg
    14461 gcatattgat tttaacaata tgccttttat aaatagtcta atttattcta tattatcgat
    14521 tatttggaat gcttttataa cttcaggtaa ttctttttct tcaggcattc taaatcttat
    14581 gaaattttta tcaagtccag taaaatcact tccagatata actcttattt ttaatttagc
    14641 aaactcttgt tgtaaatcta tgtccttgtt tttatgttca actgtcataa ttgatacagt
    14701 atcactagtt tcagctatat taaggttttt ccatggaatt agtaattgat tttttatatc
    14761 ttttgttttt tcttttaatt cttctataaa ttgaacatca tctaataaat ttgctgcaat
    14821 actacgagat atttcagaca cttcgtaagg agtagaaatc tttttaatag ggctaacaag
    14881 ttgttctgga agaactgcat atcctgctct tagtcctgct aaaccaaatc cttttgaaaa
    14941 tgtttttaaa gcaattacat tatcataatt atttagaagc ttgacagctg aattttcttt
    15001 tggcatgtat tcaccataag cttcatctac cataactgct atatcatatt tagctgcttc
    15061 ctttactata ttttcaattg atgataaagg tataatttgt cctgtaggat tgtttggatt
    15121 gtctatgtaa attactttat attctggatt tattttttca ataaattctt tttcattaaa
    15181 cttgaaatta tcctctttct ttaaaagaac ataatcataa gttgcaccat gcatttttat
    15241 atctgtctca tattctgaga actgaggtga atatcctaaa actttatctc ccttttcaat
    15301 aaatagtcta tttaaaaggt aaataacatg tatagaacca tctgccaaac aaattctgtc
    15361 agtatctaat gctataaaat ctttccaata atcgactata ttatctttta aagcaattga
    15421 atgaggatat cctcttatca tatcaaattt taaagcatta aaagcttcta cagctttgct
    15481 tgagtaagac acggtattta taccttcacc acagtctatc tcgaatacat cttctgaatg
    15541 tccagattct attgcataac tttttttcaa ctgcatttca atagctttgt taatttttag
    15601 tttcatactt tatcactcct tatttagtca ataataaatg ttataaaagt tgctagattt
    15661 aaaatattat gaaaatatat aatagtaaaa aatgaatata aatattataa tagctcactt
    15721 tatttaatat gattatatat catatattgt aaaatttcta gcattataag actataaatt
    15781 gaaaatattc agaaaaatac tacaagaaac gatttatttt gctcttaaaa taagttaaat
    15841 gaatgttatt aattttgtaa attgaaatag tttaagtata aagttatgat ataatctaat
    15901 aagggtaatt ctttagatta tattaaggaa atataggtat acaataaaaa gttatggagt
    15961 tggattatgg gatataaatt aattgtaaca gatatggatg gaactttatt aggcaataat
    16021 cataaagtta cagatgaaaa taaaactgca ctacaaaaag ttataaaaag cggtattaat
    16081 gtaactttag caacaggaag agccttcgat tcagctaaat gcaatgtaga ttttcttaaa
    16141 gaggacatgc caataatagc ttgtaatggt tcattaataa gagagcaaaa tggaaatata
    16201 atatattcaa ataagattga tacaagaaca tgtttaaaca ttttagatgt attagataaa
    16261 tacgatattt actaccaatg taatagtata gattctatgc tttcgaaaaa aatagaagga
    16321 cgtgaagata gattaagtgt atttttaggc tctgaaacag aagtaattgt aaaagatgat
    16381 ttgagagaag aaatctttaa aaaagatata ctaaaatttg taatcataga agaaaaaaat
    16441 ccatctattt tggatgaaat aagaaaagaa ttgagaaaag ttcaaggaat aaagataact
    16501 tcttcatggc caaacaatat tgaagtcatg aatgaaggtg ttgataaagg taatgcagtt
    16561 aaaattttag ctgaaaaaat gaatatagac agagaagata taattgcatt tggagacaat
    16621 tacaatgaca tagaaatgat aaagtttgct ggtcttgggg tagctatggg aaatgcagaa
    16681 gaattgatta aacaagaagc tgattatgtt acagatacaa atcaagacag tggagttgca
    16741 aaggcaattt ataaattcct agagttaaaa gaatcactta gctcttaaaa cagtatataa
    16801 taggaaaaaa taggttgact attttgtaga tagtaattat aatacaaata gataaaacat
    16861 aaaaatttag attcagtgaa aaagagagta gatatagaga aaatctcagc gaattggggg
    16921 atggtgtgag cctaatgata acactttata ttgaaaagaa ctttggagaa tactacttga
    16981 aattcagtat ggtagtaggt aatctcgcct taagagaata gagtgggtaa acattgttta
    17041 ccaactagag tggtaacacg gaatatttcg tctcttggtc tttttgacca agagattttt
    17101 tagtttcatt gagttacaag acttataatt aaaatacaaa aaattaaaat atgaggtgaa
    17161 agttatgaaa ttatggggcg gacgctttag aaaagcggaa aatcaactta tggaagaatt
    17221 taataaatct tttggctatg attgtgtact gtacaaaaaa gatatcgaag gaagtgtagc
    17281 acatgttcat atgcaagtaa aatgtggact tttaacagaa gaagaaggaa agtctataac
    17341 agaaggttta aaagggatac ttgaagatgt agaaaatgga aagttagtat tggatggaga
    17401 gtatgaagat atacatagtt ttactgagat aaatttaatt caaagaattg gagatgttgg
    17461 caagaagctt catacagcac gtagtagaaa tgaccaagtt gcagttgata tgagattgta
    17521 tgctaaagaa aaagcaaatg atttggtggg tttaatatct gaatttaaag ctactataaa
    17581 agatgttgct gacaaaaacc cagtgatgat gccaggctat actcatcttc aaagagctca
    17641 agtagtgaca tttaagcatc acttaatggc atattatagt atgtttgata gagatgagaa
    17701 aagaataaaa aatgctatag aaatattaga tgaatcacct ttaggctgtg gagctttagc
    17761 aggaactacg catgatatag atagaagtat aacttgtgaa caattaggat ttaaaaaagt
    17821 agtagataat tttatggatg gagtaagtga tagagattat ttactagagc taatgagtga
    17881 tttttcaatt ataatgatgc acttaagtag attaagtgaa gagttgatac tttggagttc
    17941 tcaagaattt ggatttgttg agatagatga tttatataca actggaagta gtataatgcc
    18001 tcagaagaaa aatccagatg gtgcagagct tataagaggt aagactggca gagtatatgg
    18061 aaacttattt ggtcttttta cagtaatgaa aggaatacca ttagcatata ataaagacat
    18121 gcaagaagat aaagaaggtt ttttcgatag tgtacatact cttgaaatgt gtatacaaat
    18181 aatggataga atgatagcca cactaaaggt aaatgaggat aaaatgaaac aagcagtaaa
    18241 aaatggtttt ttaaatgcaa cagaagttgc ggattatttg gttaaaaata atgttgcttt
    18301 tagagatgca catggtatag taggaagtat cgttatatat tgtgaagata ataaaaaagc
    18361 aatagaagat ttaacattag aagaattaca taagttttca gatgctttta aggaagatat
    18421 ttatgatttt atcgactatg agagtatatt aaataaggga ataaaaaaga atttaaaata
    18481 atgtatttat ttttaaaagc tgtaaatttg aatgttatca tttaaattta cagcttttta
    18541 ttgtgtaaga ttttattata taaaagtaag aaacttaaaa ggagtagtat ttaaaataaa
    18601 tacaaataaa aaattattat taaaatgata attaatatca ataagtattg acaaaattat
    18661 ttctaaatac tattatatat aatataaata ataatgaaaa tcaatatcaa ataaatggga
    18721 ggaaatctaa tgaacttatt agtgattggt ggtcatgaaa gaatggaaaa agattatatg
    18781 gttatggcca agaaaaaagg ttataagaca aaggtatata ctaccatgtc atctaaatta
    18841 aataattcta taggaagacc agatgcagtt gtcatactta catcaactgt ttcacataag
    18901 atgtctagaa cggttgagtc tcaagctaaa aaacaagata tattaatcgt aaggcataaa
    18961 aatagtagta aggtagcatt taatgaatgt ctagatatgg ttgatgaatg tctgggaaat
    19021 tgttcaaaat gtaagcttaa agacaaacaa aaacaaaaaa atatataggt ataaaaaata
    19081 cataaacata aaattaaaag tactgagata atagttataa ttattatctc agtactttta
    19141 gatttataag gataagtata ttataaattt tttattataa tttccaacta cttgttactt
    19201 tttcatattt tttttacttc tagctttttt tctttttttc ttctttatat ttgaagctat
    19261 tataaataaa actaaaagca ctagaatacc tgcaataatc ttaacaaaag tcattaaaat
    19321 attatttcca gtaaaaaatg gaagactgct atcaagatta ttttttgcaa ttaagtctat
    19381 actgttttct agtttaccat tattatatac atttaaagta ccaaccttag ctcctttttt
    19441 tataggcaaa tcaattttat ttaactctgt tttggtatca taattgcctt gagattcatc
    19501 tttttctaag aatatcctat aactattttt tggttcataa atcaattcat gttgttttgt
    19561 aaacaatact tttttagtat ctgtgtattt ttctttatca acaatagtag cacacttaaa
    19621 gttatcaaat ccataatcaa tcagaatacg tgagtctaaa tataaatcag cattagttga
    19681 attaaataca gcaacgataa ctcttctgcc atcttttaca gcactcgata aaagacattt
    19741 accagcagca tcagtatatc cagtttttat accatcaact atatcatatt ttatatttat
    19801 aggttgacct ttgtatgtaa tcttatcatg tgatgtcaaa aacttattag tgtttacaaa
    19861 gtatctctca taaggatatg cttttgtagc ttcaaattta agtgacttag tttttacaat
    19921 ttgtctaaaa gtatcattat tcatagcttc tctagctatg agagccatat catgagctgt
    19981 tgtgtagtga tttgggtctg gtaatccatg aggattatta aaatgagtat tagtagctcc
    20041 aatttttttt gcctcagagt tcatgaggtc aataaatttt tgtacattgc caccaccaac
    20101 atatctagcc aatacaaaag cagcatcatt agcagaatga accaaaagag catctagtaa
    20161 ctgctttaca gtaaaagatt ccccattttt tagatacata ctagagccat ctatttgagg
    20221 taaatcttta atttctatta cttgatttaa atctttaacc tcctttagaa ctaaacaagc
    20281 tgtccatact ttagttgttg aagctggata aagcttagaa tttccatcct tattatatag
    20341 tattttgcca gactcatagt ccattaaaac tgcatgttta gcaactatag ctggttcatt
    20401 atctgcaaaa gagatattag agcttcctaa aaatgaagta aatatcaata aacagattaa
    20461 taaaagtgat aaatttcttt tcattgtgag cctccaaatt ttaaattcat cttttagtat
    20521 agcatatatt tgtcaataat taaaagaaag gagtgattaa tatatgaaaa aaaaggtaaa
    20581 atttatttcg ttttttgttt tatttatttt aataatatca tcaataatcg tttataaatc
    20641 gcttattttc aaagatgata tttatgttgt aagtaaaaaa aatttaccta atgaaaaaac
    20701 acatgttgta gagaatgaaa ttaaaggtga agataataat cacaataaag taactaaaga
    20761 catagataaa aattttcaaa ataataaaat aactatatac ataagtggag cagtaaatag
    20821 acctggaatt gtaactatag agtcagacaa gagactttat gatgctgtag aattactagg
    20881 aggaacgaca aaagaagcag atttaaatgg agtcaatcta tcagtaagat tagaagatga
    20941 acaacattac ataataccta aaataggtga agcaacatct gttacaagta atgatgattc
    21001 caataaacca aatcagaaga atgagtcaag aggtgagcct aaaaataaat ccaataaaaa
    21061 tatatctaac gaatcaaaag taaatataaa tgtagcgact atagaagagt tagattctct
    21121 acctggggtt ggagaagcta cagccaataa aattttacaa cacagagaag aaaatggaca
    21181 gtttagttca attgaggaaa taaaaaatgt aaatggtatt ggagataaaa agtatgaaaa
    21241 tataaaagat ttaatttgtg tagactaaaa tataatacaa aacttacata tagatatgtt
    21301 attataaata tgtatgtata tgtgtgtaca tgtggaaatt tagtaaagga ggcactttta
    21361 tgaaaaaaga acaaaaaaaa cttacagaga tgacaacagc aggtggttga gccgctaaaa
    21421 tagggccaga ggttctggca tcagttttat ctcaattgcc taaaaatgat aatatagaaa
    21481 atttattagt aggactagat acagcagatg atgctgcagt ttataaatta aatgatgata
    21541 tggcacttat ccaaacttta gacttcttta caccaatggt agataaccca tacgtatttg
    21601 gtcaaattgc tgcatcaaat tcactatcag atgtatatgc tatgggaggc aaacctttgg
    21661 ttgctatgaa tattgtttgt tttccatcat gccatgatat ggatgtactt gcggaaatat
    21721 taaaaggtgg gtttgataaa gtgaaagaaa gtggagcact tttggttgga gggcatactg
    21781 tagatgacaa agagcctaaa tatggtcttt cagtttctgg gattgtaagt ccaaataaag
    21841 ttttatcaaa tgctactgca aaacctggtg ataagttaat tataacaaaa ccaattggag
    21901 tgggtgtatt aaatacagcc atgaaagaag gtatggtaga acaacatata gcagataaag
    21961 taatagaaat aatgatacat ttaaataaat atgcagcaat gagttttgag aaatttgatg
    22021 taaattcggt tacagatata actggttttg gtctacttgg tcatacttta gaaatggcca
    22081 aagcttctga agtaagtatt gaaattgaat caaaacatgt accaattatt gaaggtgcaa
    22141 tagaaatggc acaaatggga attatacctg ctggtatgta taaaaatatg cattatgtat
    22201 ctaaagatgt agaagttgta ggaaatatag aagttgcagt tcaagatatt ttatacgacc
    22261 cacaaacatc aggagggttg ttaatttcag taaaagaaga acttgcagag gaacttgtaa
    22321 aagatatgaa attaaatgga gcaatagaag ctaaaattat aggttctgta gttccaaaag
    22381 gggaaaaata tattacagtt ttataaaata ttatagagaa agagtgattg ttttgagcaa
    22441 aagagaattg tttgcaatgt tgccttcagt tgatgaagta ttaagtgata atagaattgt
    22501 agaaataata aatgaatatc ctagaagttt agttttagaa tctgtgagag aagtaataga
    22561 tttaaaaaga caatttatat taagattaaa agaagatgca tcaaactctg taacaataga
    22621 gtttggtgaa ataatagaat ctgcaataga gagagttaag ttaaattact cattatcttt
    22681 aaaaaaagtt ataaatgcaa ctggtacagt tattcataca aatttaggga ggtctttact
    22741 tagtgaagat ataaaagatg aattatggtg tgctgcttca aggtattcaa acttagaata
    22801 cgatttggat aatggagaaa gaggttcaag atactctcat ttaactagta caataaaaag
    22861 acttactgga gcagaagatg tactagttgt aaataataat gcagcggcag tacttcttgt
    22921 acttagcaca atggctaaag gaggagaagc aattgtatct cgtggagaat tagttgaagt
    22981 aggtggttca tttaggattc caagtataat ggctcttagt ggtgcagaat tagttgaagt
    23041 tggttcaact aataaaactc atttgaaaga ttacaaggag gccattacag aagatacaaa
    23101 tgtattgatg aaggttcata caagtaatta tagaataatg ggattcacag agagtgtttc
    23161 tatagaagaa ttggttaatt taggtaaaaa atataaacta cctgtaatag aagacttagg
    23221 aagtggagtt tttatagatt tatcaaaata cggtttatct tatgaaccaa ctgtattgga
    23281 ttctattcga caaggtgcag atgtagtaac ttttagtgga gataagatgc ttggaggtcc
    23341 acaagcaggt attatagttg ggaaaaaaga gtatatagaa aaaatgaaga aaaatcaact
    23401 tactagagca cttagagttg ataagcttac aatatgtgct cttgaagcaa cattgagaat
    23461 gtatttagat gagacaaaag ctatagaaaa tatacctact ttaaaaatgt tgacatataa
    23521 aattgaagaa ttagaagtaa aagcaaataa actatttgaa aaaataactg ctttaaactt
    23581 aaatgcaaac ataaatatag aagatggatt ttcacaagtg ggaggagggt ctatgcctct
    23641 tgaaactata agtacaaagg taatatcaat aactcctgaa catatgaatg tttcatcttt
    23701 agaaaaaaaa ctaagactta gtgaagcaca tataatagcc agagtgtatg ataataaata
    23761 tgtactagat gtaagaacta tatttgatga tgaatttgat gtaatagttg cggaattgag
    23821 aaaagcattt aattaaataa atttgagcta ataaatatta aatttagaag tataagtatg
    23881 aagttttgat taaaaaatag ctacacacac ttgtgacttt agtcatagca ggtttagagg
    23941 gggcaaaaaa tgaaaaatgt agtaattgga acagcaggtc atattgacca cggaaaaact
    24001 actcttataa aagcattgac tggaagagag actgatacat tagatgaaga aaaaaagaga
    24061 ggtatttcaa taaacttagg atttacttat tttgatttac caaacaatag aagagctgga
    24121 attgttgatg tcccaggaca cgaaaaattc ataaaaaaca tgttagctgg agcatcagga
    24181 attgatatag ttttacttgt tgtagcagca gatgaagggg ttatgccaca gacagttgag
    24241 catttagata ttctaagctt tttaaatatc aaaaatggaa tagtggttct aactaagtct
    24301 gatactgtag atgatgaatt tagagagcta gtaaaagaag atatttgtga aaaaataaaa
    24361 ggaacttttc ttgaagatgc tgaaataatt gaagttgatt ctatatctaa aagaggtata
    24421 gacactctta ttgaaaaaat agataaaatg agtgatgata tagaagataa aaatgaaaac
    24481 tctccagcaa gacttaatat agacagagta ttttcaataa aagggtttgg tactgtaata
    24541 acaggcactt taatagaagg aaagataagt atagaagatg atttagttat atatccacag
    24601 gtattaaaaa caaaaataag aagtatacaa gttcatggag aaaataaaga tacagcttat
    24661 gcaggtcaaa gaacagcaat caatatatca aatgtaaaag tggatgatat aaaaagagga
    24721 gatgttttag ctgcaccaaa ctcattagag gaatcaatga tgttagatgt aaaattatca
    24781 ttggtaaatc atttagataa aggattaaag cactgggata gattaagatt gtatcatgga
    24841 actagagaga tactttgtag agcagttcca ctagataaag aattaattga aagtggagaa
    24901 agtggctatg ttcagttgag acttgaagaa agcatagtat ctaagaaagg tgatacgttt
    24961 gtagtgagac gttattctcc aatggaaact ataggtggag gtgtaataat tgacccatct
    25021 cctaaaaaac ataagaaatt tgatgaaaaa gttatagaag cattaaaaat aaaagaaaaa
    25081 ggcgaactaa aagatataat agaagagtac ttaaaaagga atttaaaaaa ttatccaaat
    25141 ataaaagaaa taatgagcta tagtggtgct catgaagaag atgtaaaaag agcgcttgaa
    25201 gcacttatat cagaagataa agtatttatt ataggaaata tgtatatgca tataaatcaa
    25261 tacaataaat taaaagaaaa tacaataaag cttttaagtg agtaccataa gaagtatagg
    25321 cttagaaaag ggatactaaa agaagaagta aggtctaaga tagagagtaa ttttaagact
    25381 agggagatgg atattttatt agaaaaattg tctacagaaa atgctataaa aatagaaaat
    25441 aatatagtat ctctattaga ttttgaggtt attttaaatg ataagcaaaa agaaatagca
    25501 aaaaaaatag aaaaaagatt aaaatcatgt ggagtttctt ctatactgac aatagatgaa
    25561 gtttctgaag gaaatcataa ctatgctgaa gtattggagt caatgatagg taataaagta
    25621 gagaaattag atgatttgta tataatggac aaagatattt atgaaaatgc aaagaacatt
    25681 ttgataaatt atataaaaga aaataaagaa ataacattag gagaatacag agatttgatt
    25741 gattctagca gaaagaattg catgattata ttggaaaact tcgatagaaa caaaataact
    25801 aaaagagtag aaaacaaaag aattttgttt tagcagaaaa tgtctgtttt tgctttaagg
    25861 tataaagaag gaattataat gtcgagtatc gtataattaa ttagtataaa atattaatta
    25921 agaggaagtg taaagtattg aagaatataa tacctgatgt aaaaccagat ataaaagaaa
    25981 gagaagacat gagcctttta tttataataa tgggctcagt acttttatta tttattataa
    26041 aagatataga gaaatatgaa actttattac atgccatata tacgatattt ttagtagcta
    26101 caggagtaat tatatttaat actacaaaat ttaaagtaga ttcattttct acatttttag
    26161 gattaatttt tatagctact ggagtattgg agtgtatata tttatttaat tccttgggga
    26221 ttaaaactaa gtctataatg gagattaaca tcacaatatc agcaataaca gatttatttc
    26281 ctatactggg tgtatactta agttttaaat ttgttaagga taacaaacaa atttattcaa
    26341 gtataatttt atttatagca actgctacat taacaataac atctttattc ataatatcag
    26401 gaatttgtga ctatctggga aatggtaaat cacaatatgc tttaggagtt ataatatcta
    26461 tattcataat aattatttct atcattagtg gaattgaatt aaattcaagt tcaaataaag
    26521 gtaaatggga atatgatgaa aaaaagattt ttaacagaat aatagtaata ataattttat
    26581 caagagttcc aaatctattg catatagtta ttgataatag aaatgtagag cggatattat
    26641 cacagataat aataaatgta gccttatatt atttatataa ttacatagta tctaagaata
    26701 ttaagaaaac agcactggaa ttgcatgata cgaatgaaga attaacaaaa aaaacggaaa
    26761 gtttaaaaga aaagaataaa aaattaatct atgagacaga aaagatagag gaacttaagg
    26821 gaatacttat gaaaagagaa tctaggctac aatctacatt agatgtagca gtaaatagca
    26881 tagtagtgtt tagcaaagat ggagaaatta catatgcaaa taagagcttt agaaatactt
    26941 ttggagacta taaagaacaa gataaattga ctgataaaat aaaaaacttc aatgatttga
    27001 tagaaagcat tcattatgtg tttgttcatg agaagaatgc agagaaactt attagtacaa
    27061 gcgataataa agtttatcaa gctatatttg cacctttaat tattgcttca caaacagaag
    27121 gagtattgtg tgtactagaa gataagacta agaaaaagga gtacgaacgc aaacttattg
    27181 aagcaaataa gagaagtaaa gattttttag aaagtattgg agatggcata gtagtgcttg
    27241 aaggtaataa caaaatatat gttaataatg catgtaggga aatttttaaa aataatttag
    27301 agagtattga tttttcatta gtatgtaaaa gtgaagaaag tatagaaaaa agatatgtaa
    27361 tagatggtga agtaaagtat gtagagatga gtttttctca gtatactaat gctggtacta
    27421 ataaaactat tattgtaata cgtgatacaa cctctcgaaa aatatctcaa ataaaacttg
    27481 aggaaagtca atcatcatat tcaagattta tagatatatt acctgatggc atatgcttat
    27541 taaaagaaga tttaagtata aactatgcaa ataagtcgtt tttagatatg ctagctttta
    27601 caaacataga tgatataaaa gattctaata ttaaactatt aatgaatgcg aatactgaag
    27661 aaaaaatgaa atttacggat aatatggcta aagttttaaa tgaaaataga agtatacttt
    27721 tactggaata tgaattgata aatagttatg atgatatagt agaagtagaa ttaagtgcat
    27781 taccttttgc tatatacaat actagataca taatgcttat tataaaagat ttagtacata
    27841 agaaatattc cgagcaagca gaaaaagaac tgcttgaaag atttaaaaca gataaaatca
    27901 aaacggagtt ttttgcaaat atgtctcatg aattaaaaac tccactaaat gttatatcta
    27961 gttcaaatca actggtagat tctttctata gaaatgaaaa gataaaagat tacaataaca
    28021 atattaaatc tcatgtggat ttagttagac aaagttctta taggcttcaa agattaataa
    28081 ataacattat agatttaaca aagatggagt ctgggttcta tacactaaaa cttgcgaaat
    28141 acaatattgt atctgtaata gaagacttat ttatgaatat agaagagtat gcacttagaa
    28201 aagacataaa aattcttttt gatacagacc ttgaagaaat taatgtttat atagacaagg
    28261 ttgaaattga gagaattatg ttgaatctat tgtcaaactg tattaagttt actgataatg
    28321 gaggctggat atatgtaagt attcattata aaatagataa agtaatcata agtgtaaaag
    28381 acactggagt tggaatacca caagataaat tagaattgat ttttgaagaa ttttcacaag
    28441 ttgataagac tttatccaga aatactgaag gaagtggaat agggcttgct atagttaaga
    28501 atctagtaag tcttcatggt ggagatatag aagtagtaag tgaagtgaat aaaggcacag
    28561 agttcttaat ttcacttcca atgaagggat ttagtagtga acattacaca gaagataaga
    28621 gaatatataa tattcaagaa aaaataaaaa tagaattttc tgatatatac tattaaaaat
    28681 gattatgagc aaaaataaaa taaaaatact atttgtttaa atatttaagt tgtaagaaat
    28741 aggctatcat aaggtaaatt attatgatag cctattttta gctaggtttt atatctatat
    28801 gtgagaacat ataatctcta aattaccttc aaaactaaaa tctccaaagt cgtttggcag
    28861 tataaaatgc ataccctttt ttaaattata ttctacagaa ttgtgtataa gttttccatt
    28921 tccatccaac acactgtata aagaaaaagg tgtattgtgt gtaaaattac attttccaaa
    28981 aacatctaat ttataaacac taaaaaattc gtttgacaca aatgttgtgc atttaaagtc
    29041 tgatgttgat acgattttat agtcagtatc gaaatttata tgaggaacat tcgtaacatc
    29101 tattgatttt tgaacatgaa gttcacgctt attacctgaa ttgtcagttc tatcataatc
    29161 atagactcta taagtagtat ctgagttttg ttgagtttct aaaatcaatg ttcctttgca
    29221 tatagcatgt atagtaccac ttggaacata gaaaaagtct ccctttttta tattaacctt
    29281 tctaagtagt ttgtcccatt cattattatt taccatattt acaaattctt tatgagattt
    29341 tgcattatga cctattataa tttctgcatc atcagaacaa tctattacat accaacactc
    29401 tgtcttacct aactctccat tttcattttt cttagcatat tcatcatttg gatggacttg
    29461 aactgataaa ttatcatttg catccaatat ttttgtaagt aaaggaaact tatcaccagg
    29521 tgtgtttcca aataattctc tatttttatt ccacaattca gatagttttt tacctttata
    29581 ttttccattt tctattaagc aatctccatt tttatgagag cttatagccc aacattcacc
    29641 agttgttggc gaatctattt cataattaaa tttatcttta agtgcagtac caccccatat
    29701 tctatccata aaaataggtt ttaaaaataa tggttccata atcctgttcc tcctatgata
    29761 ttaaatttat cctacaaata attatatata aatagattat aaaatcaata gtaaaaaagt
    29821 tttgtccctt gaaatgacat aaagtataag gagttattaa ataagataaa ctatgatata
    29881 taatataaag ttctaaattg gagtgataat tatggagttg tttaaggcag aaagcaaaaa
    29941 atatgaaaaa gaatttttaa aattattgga gcaatgggtt agtatacctt cattttatga
    30001 tagaaaaact gtatctaaag atatgccttt tggaaaagga gtatatgatg cattaaactg
    30061 gtttgaaaat ctaggtagag aaaacaattt caaagtaaaa aatatagata atcatgctgt
    30121 tcaaattgaa tatggaaatg gtaaagaata tgtagatata tttggacatt gtgatgttgt
    30181 aaatccaggt gaaggatggg atagtgaacc atttaaacta aatattatag gtgataaatt
    30241 agttgctaga ggtgtatctg ataataaagg acctatgata gtgaattttt tagcactaaa
    30301 aatgataaag gatttagata ttaatttaaa aagaaaggtt agattaatag ctggaggaaa
    30361 tgaagagagt ggatttaaat gtataaagca ttattatagc aaagagccat atggtgtatg
    30421 tggatttact ccagatgcta aatttcctgt attaaatgga gaaaaaggtg gagcaataat
    30481 aaagttaatt tcaaatatag acgataaatc tttatatata agtggtggaa tagagtttaa
    30541 tacaatacca gataaagttt atataaagaa tgtagaaaaa ttgggtaaag ataatatatg
    30601 ttttgatatt aacaatatat cgataaatta tgataatggc aattatattg tgtatggaaa
    30661 aggtggtcat tcatctaaac ccgaaaaatc aataaatcct atattagcta caattaaact
    30721 tttgtcagaa aatattgatg aaaaatggac aaaagattta tataagttga taaatcaaga
    30781 taatataaat ggaaacttat ttggtttaaa tattgagggg aaatgtggga ttttatcaat
    30841 agtgccaaca ataataaata tagtagatgg aaaattagaa gtagttttaa gcgttagata
    30901 tccagaaata ttaaccattg aagatataat aaaaaaattt aatttgtata tggagcaaaa
    30961 taatattaat aaatttgagc ttattgggga aaatttaaag caagcaaatt atatagatag
    31021 aaattcaaaa cttgtaagaa gtttgcatga tatatatata aagtattctg gagatttgaa
    31081 aaatgatgtt agagtaacta gtgcaggaag ttatgcttct gaaatgaata attcagtaat
    31141 atttggttgt gaatttcctg atggtagctt tggcaatgtc catagtgcga atgaatttgc
    31201 tagcttagat agatttataa ctgcaatagg tatatatgca gaggcaataa ttacattatg
    31261 taataaaata taaatacaaa atgtccctta tatagacata ttatatatac aattaaaatt
    31321 ttacttgata tataattgaa atcaaagaga aggtgataca atgataacta agaaacatgc
    31381 aataatagta aagagtttaa gcaataaaga tggatatatg acatcaaacg aattagctat
    31441 caaattggat gtgtctacta aaactattaa aagatatata gcagatttaa atagtgtttt
    31501 aagcaaatat gatttggtaa tagcttcttc tagaggtata ggatacaagt taagcggttc
    31561 taaaaacaat atagccagag ctgttaaaga agcaaataaa tatattgatg gttttttaga
    31621 tgactctgaa gagtcaagaa tgtcaaatat aatatgtatg cttattaata gaaattatat
    31681 gagtatagaa gcaatggcag aagaattaaa tctaagtata gccgctataa ataaattgtc
    31741 tagtaagctt aaaagaaaac ttgaaaagta tgacttagtt ataaaatcta aaccttacta
    31801 tggaagctat atacatggtg aagaaattaa tataaggcaa ttaattactg actatgcaat
    31861 aaaattagat gaaaaaagta aagtgaaggt gtttttagat gacattagtg aaaacgatat
    31921 atactgtata gaaagtattt tagaaaagca cttaagagaa aaagatacaa taatttcaga
    31981 taaagatttt aatcttttgc tttcaaaaat aattgtttct gtatttagga gtaagagagg
    32041 tcatagtaac aatataaact taatggatac aagttataga tttcataact actactttat
    32101 agaaaatcta atgaaagaaa tatctgataa aattggattt aaacttattg aagatgaagt
    32161 aatttatatt tcaaattatt ctggtgtaat agcttataaa ggtacacaag gaagaaaaaa
    32221 cacaagtgaa attgaggaac gaataagtag tgttataagt agtgcacttc aagatatatt
    32281 ccttatttca ggtagtgatt atacaaaaga tgatgagttt atggttgcaa tctctgacca
    32341 tataaagaga tttttaaata gagctagagc taatgtaaaa tcaaataatc ctttacttca
    32401 tcaaataaaa gagaagtttc ctatagcttt taatttagcc gtgtttttat caaataaact
    32461 agaaactgag tttaatttaa aacttgatga agatgagctt ggatatatag ctatccactt
    32521 tgctgcttca aatgaaagaa tgaaaaaaaa tactagtaag aaaatttgta tagtttgtca
    32581 ttatgggata ggaacaggac aacttatttc tgaaaagcta aaacagaata taagtgattt
    32641 aagtgttgta ggtgtttatc cagttagata tcttgatatg gctataagtc aagatgttga
    32701 tttgatagta tctaccgttg aattaaaagg atatgaaaaa cctgtcttat atatagaaaa
    32761 tatatttgat gatagcttaa ttgaaaacgt aaacaaagcc ttttatgaaa aggaagaaag
    32821 aagaaagata ataagtaaca tgtttgatga aaaagctttt ttcagtataa aggctagtac
    32881 taaagaagag gtcataattt cactttcaaa taaactaaaa gaaagagatt ttatagagga
    32941 aagttctata aaaagtataa tagatagaga aaatatttca tcaactgaaa taggaaatct
    33001 agtagcaata cctcacacaa tagtgaaggg agataaaaaa tctataatag gagttggaat
    33061 acttgaaaat ccaataattt gggataagca agaggttcag ctagtattta tggtattttt
    33121 taatactaaa gaaaagcata atttctcgat atttaaatac ctttataatt ttataaaaga
    33181 tgaaggagga gtaagaggaa ttattaaaat atgtgacttt aataaattaa tggcactgat
    33241 aggtaattaa ggaggaaatt aataatggga acaaacatat ttaacaaaga atatgtattt
    33301 ttaaatgttg atgctaagtc aaaggttgaa gttttaaaat ttatatcaaa aaaagctaaa
    33361 gacttaaatt tggcagaaga tgagagctta gtatatgaag gtttaatggc tagagaagaa
    33421 caatttacta caaatttagg agaatctata gcaatacctc acactaaaaa tgatgcaatt
    33481 gaaaatccag cagtagtagt attgaagttt aatgaagatg ttgtttggaa tgaaggtgag
    33541 gataaggtta aattagcaat aagcttactt atgccaggaa aaagtaaaga gaatattcat
    33601 cttaaattat tatcatctct ttcaagaaaa ttaataaata aagaatttaa agattctctt
    33661 ttaaaaagtg ataatgttga agaaatatct aacttaataa atgaagcttt aggtttataa
    33721 ttaaatacta aggttataaa ataaaaaaat aattaactaa aaataggagg aatttgaaat
    33781 gaataaaaaa ttagtagcat tatgtgcttg cccaatggga ctagctcaca ctttcatggc
    33841 agcagaagca atagagcaag cagcaaaggc attaggttat gaagcaaaag ttgaaactca
    33901 aggtgctgat ggtgtacaaa atgagttaac aagagatgat atattaggag caactatgat
    33961 aatacatgca gtagcaataa caccagaagg tatggaaaga tttgatggtt gtgaagttta
    34021 tgaagttgaa ttacaagaag ctataaaaaa tgcagaaggt gttataaaag aaatagaaga
    34081 agatttagga atataataaa tttattgtgg aggaaataga atggcaatta agaaaaaagt
    34141 tataaacagt tcaggtgctt ctacaacagg aggaaataat gtaggaaaat ctactccatc
    34201 tagtccaact caatcaaagg gaaatggaaa atggaaagaa ataagtaaac atataatgac
    34261 aggtatatca tatatgatac cagttttagt aatgggtgga cttatagggg ccttatctca
    34321 attaatacca tatgctatat taggacttga cccatctgta ggtatagttg atgctatgaa
    34381 ctcaggagaa tttacagggt tcaagcttag tcttttaaat atagcacaat taatgtcaaa
    34441 tttcggattt actttgtttg gatttgcgat accactgttt gcagcatttt gtgcaaactc
    34501 tataggtgga aaaacagctt taattgcagg atttataggt ggatatatag ctaataaacc
    34561 tgtaggtgta ccacaattca ttgatggaca atggactgaa gttgttccag ttgcatcagg
    34621 atttttaggt gcaatactaa tagcattcat aataggatat tttgtaaaat ggttaaataa
    34681 atctataaaa gtttctcata actggttagc ttttaaaaca acatttttaa taccattaat
    34741 agcgtcatta gcttgtatgg tattgatgat atttataata actccatttg gtggattaat
    34801 taatgaaagt atgaaaaact tcttaacagc agcaggagca gctggagaat atgtatatgc
    34861 aacagctttg gcagcagcta cagcattcga cttaggagga ccaataaata aagcagcagg
    34921 attcgttgca cttggtttaa ctacagagaa tgtacttcca ataacagcaa gaacaatagc
    34981 tatagttgtt cctccaattg gattaggatt aacaacatta ttagataaaa gattagtagg
    35041 aagaagagta tatgatagac aattctatca agcaggaaaa acttctatat tcttatcatt
    35101 tatgggtata tctgaaggag caataccatt tgcacttgag agaccaggtt ttgttatacc
    35161 tttaaacata gttggaagtg taataggagc tattacaggt ataattctag gagcaattca
    35221 atggttccca gagtcagcta tatgggcatg gcctctagta gataacttat ttggatatat
    35281 aataggtata gcagttggtg ctatattcat agcagtagga aatatattct atagaaataa
    35341 attaataaaa gatggtaaac ttgttgtaga ttatatcgac tagtatttaa tttttactat
    35401 ctataaataa ctttggctgg taatatggtt ttaatcaata ttaccagcct tacctatatg
    35461 attaattaaa ggcggtggag ataagatatg gataagatag aaaaagtaag agagtatttt
    35521 agagaatatg atatagatgg atttcttata aatagtccta caaacaagtt ttatgttgga
    35581 aatttattta gctcttcagg ttatgttttt ataacgaaag aatcacaata tataatagta
    35641 gattttagat attttgaaga aattaaaaga aaatctagtt tgtttaatgt agtattaatg
    35701 gacaaaacta gaactcattt tgatataatt aatgatattt gtagagagca gaatataaag
    35761 gaaattggat ttgagggaaa tgaagtatct tttgatttat atagaagtat gagtaataag
    35821 ttaagtgcaa ccttaaaatc agttgattta tctacattaa gggaaacaaa aaatgaagac
    35881 gaaataaaat atataaaaaa agcttgtgaa atagttgatg ctacatttta tcatatagta
    35941 gactttataa agattggtat gactgaaaag caagttgaaa atgaaattgt tagaattata
    36001 aaagatttag gtggtcaaaa agaatctttc gatacaatag ttgcatctgg gcttagagga
    36061 gcattacctc atggaaaagc aagtgaaaaa attatagagt atggagattt tgttactttt
    36121 gactttggtg ctaagtataa taattattgt tcagatatta ccagaaccat ttgtatgggt
    36181 actataaata aagagttaga agaaatatat aatatagtaa gaaaagctaa tgaagagtgt
    36241 ataagagttt taagaccggg aatgactact ggagagatag ataaagttgc aagagacata
    36301 attggttcat atggatatgc caataatttt ggtcataatc tgggtcatgg tgtaggaatt
    36361 atggttcatg aatatcctgc cttagctcct gaatcaaatg aagtattaaa agaaggaatg
    36421 attgtaacta tagagcctgg tatatatgtt ccaagtcttg gaggcgtaag aatagaagat
    36481 gatgtactca taacacaaga tggatgtatg agattgacta catctactaa ggatttaata
    36541 gttgtaagct aaaaataaat tagataaata ttttataaca ataagaaaag aagaggtaaa
    36601 tttaaatgta taattttgat gataaaccag atagagtaag tgaaaagtgt agaaaatggg
    36661 atttaaatat tataagagat aaatttggag atattagaga agattttgta ccaatgtgga
    36721 ttgctgatat ggattttaaa ataccaacag aaatagaaaa caaatttatt gaagctgtaa
    36781 gaagaggtgt atttggatat acatactgtt atgatgaatt ttatgattca gttattggtt
    36841 ggcaaaaaaa tatgcatgag gtaaatgtag aaaaagaatg gattacatta acttatggaa
    36901 ctgtatcaac acttcattat gtagtacaag ctttttgtaa gaaaggtgat agtataatat
    36961 taaacacacc agtttatgac ccctttgaat catcagcaaa aaaacaaggt gtaaatgtaa
    37021 tttgtaatac attagatgtt gtaaatgata gatattatat aaattttgat aaattagaag
    37081 ttcaaattaa agaaaataag cctaaattaa tgatgttttg tacaccacat aatccatctg
    37141 gaaggatatg gacaattgaa gaaatgacaa gggtagcaac tatatgtaaa gaaaataatg
    37201 ttattttggt tgcagatgaa gtacatgcag agcatattca ttatggtaaa tttaattcaa
    37261 tacttaagat tggaaaagag cttttagaaa atgttattct actgacatca ccaaataagg
    37321 gctttaatct tggtggatta aagacttctt attcaatagt tataaataag aatataaggg
    37381 ataaatttag aaataaatta aagcaaaatt ctataacttc tccaaatgtg tttggaataa
    37441 taggattgat aaccgcttat aatgaatgtc atgagtggtt aagtggtgta aatgaatata
    37501 taaaatcaaa ttatgaactt ttagaaactt gggtaaataa atataataag ataaaattga
    37561 tgaaaatgga atcatcttac ttagcttgga tggatataag tggattaggt ataagtgcaa
    37621 gtgagtttac agataaattg gctatagata caggagtatt attagaagat gggagtcatt
    37681 ttgtaaaaga tggtgagaag tatgttagaa taaatttagg aactcaaaag gaaaatgtaa
    37741 ttgaagcttt aaatagaatg gatttatttt taaagtcttt ataaaaattt ggttgaatta
    37801 gtattttata taaatttaag ctattaatat ggtatataca taagtagaat ttgttttaga
    37861 ttacttaagt atataccata ttttatataa aaattaaatt tgcattagtc atgtgataac
    37921 tatttaaatt catatgtatt ttgtatgtat aatagatata attattattt aaacttattg
    37981 tttatttaat ttttcaatag aaaaagattt atctgtaagt ttaaaattat cttttatacc
    38041 cttagttaaa tatactttct tatccttagt tatgaatata gcatctacat tatcaatttc
    38101 attaattaaa tccatacctt tttcaagacc aagtccaaat gtagaagtgg ataaggcatc
    38161 acaattaata gatttatcag aaattattgt aacactactt agattgtttt caaaaggata
    38221 ccctgtaaat ggatttaaca tatgatgata tatttttccg tctttttcga taaatctttc
    38281 ataaattcca gaagtaacaa cagatttatt tgtggtttct atgtttccta tggattcacc
    38341 atttttacta gtggggtctt gaatgcctat tttaaaaggt ttatcatttt taccatcttc
    38401 taaagtaaat atatttcctc ctaagtttac taaacctttt tttacgtcct ctgattttaa
    38461 ataggctaca attttatcag cagcatatcc tttagctatg gcacctaaat caattttcat
    38521 attttctttg gttaatttta tagatttatt tttttcatcc aatatgatgt tcttataatc
    38581 aataagaggc agaagttttt gtatctcaga atcacttgga actttagctt tatctgttcc
    38641 aatagcccat aaatttgata atggaccaat tgttatgtca aaatatccat ctgataattt
    38701 ggaatattgt atagcttctt ttacgacgaa aaatgtatca tcagaaactc tgacaaattt
    38761 tttaccagca ttatcattta ttttagaaac atcacttcct ggtatatgag tgctcatttt
    38821 gttgtcaata tatcttaaaa ttgaatcaca ttcatttaag attttatcac ttttggattc
    38881 ttttacatta aatatagtaa cttcgtttac tgtaccaagg tagtagctag ttttactata
    38941 tttagtattc tggcttgaac tcctaaaaaa tgaaaataaa attaatgcta aaatcaatat
    39001 cacaaaaata aatgtgattt ttttcttatt catggtatat tcctcctatg aaattgtgtt
    39061 attattttat tataacataa tttcatagga ggacaaaaaa tgaagaaaaa agacattctt
    39121 cttattttag gcattttggt tgttattata gcatgttatg ggataataaa tgttataaat
    39181 tctaaaaatg ctggaaatat tgagatttat gtagataata aattgtataa aactgtttca
    39241 ataaatgcca aagaagaatt taaaatagag aatagagggg ggtataacat agtaaagatt
    39301 catgataaag gggttgagat agtagatgct tcatgccctg ataaggtttg cgtacatact
    39361 ggatttataa acaagccaag tcaaagcata gtttgtatac ctaatagagt gagcataaaa
    39421 ataaatacaa atgaaaagaa tgataatcaa gaagatataa tttctaaata aaataataaa
    39481 aataattgaa aggaattggt gataattatg gttaacttag gaaacgattg ggatgaatta
    39541 ttgaaagaag aatttgaaaa agattactac ttaaacttaa gaaaatttct tatagaagaa
    39601 tataaaacac gccaaatttt cccaaatatg cacaatatat atgaagcttt aaaacacact
    39661 tcatacaaag acacaaaagt cttaatatta ggacaagacc cttatcatgg agataatcaa
    39721 gctcatggtt tagctttttc agttcaacca caagtgaaaa ctccaccatc tctattaaat
    39781 atgtataaag aattaaaaga tgatttaggt tgttttatac ctaataatgg atatttaatg
    39841 ccttgggcag accaaggagt gttactttta aatactgctc ttactgttag agcgcatgaa
    39901 gctaattctc ataagaacaa aggatgggaa attttcactg atagagtaat atctatttta
    39961 agtgagcgtg aagacccagt tatttttgta ctatggggaa gtaatgcacg taaaaaagta
    40021 gagttgattg atacaagtaa acattatatt ttggaagcac ctcatccaag cccattgtca
    40081 gcaagtaaag gcttttttgg atgtaaacac ttctctaaga taaatgaaat tttgaaaaag
    40141 ctaggaaaag aacctattaa ttggcagata gaaaatatat aaaagtaaaa ggtaacaaaa
    40201 tgataacaaa acaacaataa acaatgacat tgttgtaact aatagaaata tgcttaaata
    40261 gttgaaaata ctatgtatgc atatttctat ttttttgtca agttgacaac tcttgaaaaa
    40321 atagttacaa tttagttaca caaaaaacac aaataaaaaa agaaacttac aaagcagaat
    40381 tttatgaagc aaaatatata gtgtaaaaaa ttttagggag gaaattttat atgaatttta
    40441 aaaaattgag taatgctaaa gtctcggtaa tggcagttgt tttatcagtt ggaatattat
    40501 cgggatactc tgcgcttaat aaacaagtaa cattagtagt aaggggagaa gaaagaacta
    40561 tatcaacatt tagttctaat gtaggagacc ttttagaatc tcaaaacatt agctatgatg
    40621 caaatgatat agtaacttta gatgaaaata caaagttatc taatggagat aaaatagaag
    40681 taattgatgt aaaggaaaaa acagttgtag aaactaaaga cattccattt gaagttacag
    40741 ttgttgaaga tggctcttta ttaaagggtg attctaaggt taaagaagaa ggaaagtctg
    40801 gtaaaagtga attaatatat aaagaaactt atcacaatgg aaagaaagtt gaaaaggaat
    40861 ttgtgaaaaa ggttgttaaa gctgagccag taaataaggt tgtaagcaaa gggacaaagg
    40921 tagaaatgca agtagcctca tcaaggggag aaagttcaag aagaatggct tcatcatcat
    40981 ctagtagcag tagtagtaac aatggtaaaa atatgagagt ggtagcaact gcatatactg
    41041 gtcatagtat aactgcaaca ggaacaaaac ctaagtgggg aacaatagct gtagacccta
    41101 aggttatacc atatggaact aaagtttata tacctcaatt tgacatggtg tttactgcag
    41161 aagactgtgg tggagcaata aaaggaaata aaattgatat ctacatgaat gattcaaaaa
    41221 cggtttataa ctggggaaga aaaactatag atatacgtat attaaaatag ttaaataatt
    41281 tatattttta ctggaaatta tattttgatt atatagagaa gaaactcttt atagattctt
    41341 aaaatataat ttccagtttt tattttggat atgtaataaa acaggtaaat tttaaccatg
    41401 tatagataaa agctatttaa attataattt actatcagat aaatctataa aaattgttgc
    41461 aaagagtcaa aatatatgat attatagatt tcgttgagaa ggatttcatt atgggagtgg
    41521 atgggtgccg gtgtgccctc tagtcttcaa aactagtatg aggggttaag agcctcttag
    41581 gtgggttcga ttcccacgca ttcccgccaa tatgcaaaag gtatctttta attaaaagat
    41641 acctttttaa atttatttta agataattta tttttaataa tatataatgt tttgtattat
    41701 ataatgtaaa ttttctaata ctattatata tttagataaa aatctaggag tgtggaaaga
    41761 tggaaaataa ttttacaacg agaactagtt ttctagttgg agatgatggg atagaaaaac
    41821 ttaataattc aaatataata gtatttggag ttggaggagt tggtagtttt actgttgaag
    41881 ctttagcaag agctggagta ggcaatatta ctattgtaga ttttgatgat gtagatataa
    41941 ccaatataaa tagacaaata ccagccctac attcaactgt aggaaggtac aaagttgatg
    42001 tcatggaaga aagaatatta gatataaatc ctaatatcaa tataaaaaaa ataagaagtc
    42061 tttataataa agatactagt gacgaaatac taactgaaag atatgattat gttgtggatg
    42121 cgatagacat ggtaagttcc aaaatacatc taattgaaac ttgtgaaaaa aaagggttga
    42181 aaataataag ttctatgggt atgggaaata aattagaccc aactaaaata gtcgttacag
    42241 atatacacaa aacaagtact tgtcctctag ctaaagttat gaggaaagaa cttagggata
    42301 gaggtatcaa aaagttaaaa gtagtatatt ctactgaaca accaatagaa cttaagaaga
    42361 aagtaatgaa tggtagaaaa gtaacacctg gtagtgtatc atttgtccca tctgtaggag
    42421 gtttaataat cgcatctgta atagtaaatg aactattagg acaataagtt ttaaatattt
    42481 taatttataa attttatata caaatttgaa ggctagaagc atgaatataa agcaatttta
    42541 tattcatact tttagcctaa ttattttata ttaccttatt ttatgtagtt gtagttttat
    42601 tttttagatt atgtatctat ttcataatta tattttgtaa atataatttc tccatcacta
    42661 taaaaaacaa tatctcctat tctatctgtt ctataaattg atacatggtt ttgttttaga
    42721 ttattaataa cctccctatg tggatgacca tattgatttt tatatccaca tgatattgca
    42781 gctatatctg gactaatttt ttttataaat tctaaagatg aagaagaatt acttccatga
    42841 tgacctattt ttataaaatt aatattattt aatttaaaag aatgtaaaat ttctttttca
    42901 ttttcttctt cagcatcacc cataaataaa aaagaattat cgttaaaagt taatttgaaa
    42961 actatagaat ttaaattaga ttcttcttgt atatatgatg gacttaatac atatatattt
    43021 atattgttat ctatgtttaa aacatcattt ttatagagat gctgaataga taagttttta
    43081 tccgtacaag aatttattag attttgataa gcctcactat cagttgattg ttcaggcata
    43141 tatatggagt ttacattaaa tttttttata acattatcaa gacttcctat gtggtctgaa
    43201 tctggatgag ttgctattat aatatcaata gtttttattc ttttttgtct aagataacta
    43261 ataattatat tttcgctatc ttcatcacct ccatcaatta atatattctt atttgtgggt
    43321 gtttgaacta aaatactatc accttgtcca acatcaatta tatgtataga tagtagagat
    43381 tttttgtcac agccgattaa aagtgatatt ataataagta ttgataaaaa aattttattt
    43441 ctcaataaaa aatcactcca ttcattacat gtttatataa atttatgatg ggtaatataa
    43501 gatatatatg acttattata ttttatattt taaacaatat aaatgaaatt aataccataa
    43561 taaatttgga gttttttata tatacaaaat aaaattttta aaattaagca ataaaaaagg
    43621 taggaggatt ttatgttttt caaagatatt gaactaaatt caaaaaaaga gttagaccca
    43681 tattttgatt tagtagatta tgaagcttgt gagtactgtt ttagtacttt atatatgtgg
    43741 caacatgttt ataagacagg atattatata ggtgaagatt ttgccgtttt agttggggaa
    43801 tacgaaggag atagtttctc aatattacca cttgctaaaa aagataaact tccagaagtt
    43861 gtagattttg tccttgaata tttttctaaa aataataaaa aaatatactt aagaggtatt
    43921 actactgaag tagtagagtt tttaaaagaa aaatatccag gtagatttga gtatatagaa
    43981 gaaagagatt tatttgacta tatttatgat gcagaaagtt taagaactct agctggtaaa
    44041 aagaatcaaa agaagagaaa ccatataaac tatttcttaa aagagtatgc aggtagatat
    44101 gaagctaaat tattagataa agaaaacttt gacgagtgtt tagtactaat gaaggaatgg
    44161 gaaagtaata aggaagaaaa taatgaattt gatgaaagta tggatgacga attaataggt
    44221 atcaaaaaga tatttaacca ttatgacata ttaaaagata aggtaaaagt gtttggtgtt
    44281 tatgtggatg gaaaattaga ggcttttagt ataggagaac ttttaaatcc aaatatggca
    44341 ttgattcata tagaaaaagc taatcccgat ataagaggtc tgtatccatt tataaatcaa
    44401 caatttttgg taagtgaatt taaggacgtt gagtttgtaa atagagaaga agatttaggt
    44461 attgaaggat taagaaaagc taaactttct tatcatcctt gcagatttgt tgaaaagtac
    44521 agtgttaggg aggcttaata gactatatgg agattaggta tgctaaagaa gaagagatag
    44581 aaagtataaa agagatttgg agttattgtt ttaacgatac ggagagtttt atgaagtact
    44641 attttaatga taaatataaa tctgaaaata ctgtagtagc tttagatgaa ggaaaaatta
    44701 tttcttctct tcagctaaat cagtataagt tattactaaa tagcaaggta tataatacat
    44761 catatgtagt aggagtttct acacttccag agggaagagg agctggatat atgaacaaag
    44821 taatgaaatt tactttaaac gaattgtata aaaaagggca attagtttct atattgatgc
    44881 ctattgacta tagactttat agaagatttg gatatgagca ttgttacgac cagattgaat
    44941 atactattaa cacagatgat ttaaaaaatt ttaagtcaag tggaaaaatg ataaagtcta
    45001 atttatcaca aattgatgat ttgatacgaa tagatagaac ttttttaaat gaggttaatg
    45061 gtaatgtgtt aaaagatgaa cattattatg aaaacttatt taaagagatt caaagtgaag
    45121 atggattttt atacattcat gaaggaaatg aaaaagatgg atatatagtt tattttcttc
    45181 aggaagataa aatgtttgtc agagagttat tttataaaaa tatagatgcc cttaaatcaa
    45241 tgcttaaatt tatatataat cacaatactc aatgtaagat agttactata tctactccta
    45301 caatagataa gataagattt atattagaca accctaaaga tagtgatata aaaataaaac
    45361 cttttatgat gggaagagtt ataaatgtaa agaagtttat tgaagatata gatattgaga
    45421 aggatattaa tagctcattt aatttattaa tagaagacaa gtttatagat gaaaataatg
    45481 gtctatttaa aatttctata cagaataaga aggtatctgt agagcagtta gataaaaaag
    45541 gtgcagaaaa gcctcaagaa gattttgata ttaaattaga tataaatacc ttaacacagt
    45601 tatcattttc ttatatagat gtaaatgaag ctattttctt aaatgatata aaagatgttt
    45661 cagaagaaac actagaaaca cttaattgta ttttttctaa aaaaaatacc tatataaatg
    45721 aatatatata ggtagaatac gttaaaagat tttaaaaatc ttttgacgta tttttttgtt
    45781 tagataacaa tttatcttgt ttaaaaattt tctatttgaa aataatctaa ataatatact
    45841 tttatatggg agtgattata attcaaataa gaagaccatt attaattata ttaatgtttg
    45901 tggtagctat atcatttatc attacaaata acacaaaaaa cgacgaagaa cttaatgata
    45961 agataataac tatacaaggg gttgtcaaag gaaaaattga aaagaaaaga tacaatcagt
    46021 acaaggtagg ggtttttcta ataaatgatt atacaaaaaa taaaaatttg aagattggtc
    46081 agaaagttaa tattacaggt aaattcaaaa gtttagataa aatgaagtat gatgattttg
    46141 attatggaag gtatataaaa agtactggat ataaaggtat agtgtatata aataactata
    46201 aaattattga taaaaataaa ctttactctt taatagggga aataaagttt tatattagta
    46261 aaacttatag gtacttatat aagaaaaact cagattttat aaattctata ctattagcag
    46321 aagttgaaaa tttgactgag gaacaaaaag aaatttttac tagaactgga actagtcatg
    46381 taatatctat atcaggtctt catacaggaa tattatgtgt aattatatcc tttctattaa
    46441 gaggtataaa taaattgtat aaattattaa tactgtcgat ttttataact ttatattgta
    46501 taatggtagg tgcgtctcca tccataatta ggtctatagc atttgttatg attttttatt
    46561 tatcaatatt tattgataga aagaaagatg gaatatcagc attgtctcta attgggataa
    46621 ttttaattat gaataacccc tatgttatat ataatgtaag ttttcaattg tcttttttag
    46681 ctacactttc tatattaata ttctataata aaataaatag tattataaaa ttaagtatgg
    46741 tatcattgac aatatcatca aatatattaa ctttacctat aatttattat acatttaaag
    46801 gtataccatt gctttcaatt ataggaaatt taattatagt accatttgtg ggagtaataa
    46861 tgtatttaag tattgcaagt ttaatcgtat ttaaagtaag tgtagtaata gctaaaatta
    46921 tatctttttt taatagtaca ttgatagaaa gcatattttt tttactagaa aaaatcagca
    46981 atttaagttt tgcatacatt aatatagaaa gtcctaaatt ttatattgtt gttatttatt
    47041 acataggagt gtttttttac atattttaca tagaaggaaa agagataaag gagcaagaga
    47101 atgaattaca aggatattat aaggaatgta aaagagaaaa actttgaaaa aatgtatctt
    47161 ttttatggaa gagagtatta tttaattgag aatgcaataa aagcatttaa agatagtcta
    47221 aacgaaggaa tgcttgattt taatttagat ataatagatg ggaaggaaat agtcttaaat
    47281 cagcttataa gctctataga aacacttcca tttatggatg atagaaagat agtaataata
    47341 aaagacttcg aactattaaa aggaaagaaa aagaatttta cagatagtga tgagaaatac
    47401 ttaatagagc atttagataa tattccagac actacaacta tagtttttgt tgtatatgga
    47461 gatgtagaca aaagaaaatc attagttaag aaaataggaa acaatggaat tgtttttgat
    47521 tgtgataagc tttctgatat ggatttattt aaatggataa aaaaatcttt tgctttaaat
    47581 gatgttataa tagataattc tcaaatcatg tattttattg aacaagaagg atacagagat
    47641 aagagcagtg aaaagacatt atctgattta gaaaatgaaa taaataaaat aagttccttt
    47701 gttggtaaag ggaataatgt aaccaatgac gtaattgata aattatctca aaaaaaagtt
    47761 gagaatgata tatttaaatt aatcgattat attggagaac aaaatgcttc taatgcaatg
    47821 aaaatattaa atgatatgat acaagaaggc gaatctgtat taggtatatt ttctatgata
    47881 gcaagacaat ttaaaataat tatgcaagta agacagttac aacttgatgg atattcaaca
    47941 aaacttatag ctgataaatt aaaaatgcat caatttgttg taggaaaagc attaaagcaa
    48001 actaaaaatt tttctgatga tataattgtg gaaatattaa actatatatt agaaagtgat
    48061 tataaaataa aaacaggtct tataagagat actttagcag ttgaaatgtt ggttagtaga
    48121 tactgtaaaa gagaagcaat ttaaaaaatc tatatattaa taaaaaataa atagcaagat
    48181 atgttatagt tcagagtaga tgtaagctaa attaagtttg atatacaatc aactataata
    48241 tgtctaacta tttatttttt attgtataaa tttacaaaat aaaaaacccc tacatagggg
    48301 ttattatata taagaaatat aaactggtaa ttaagcgttc ataccgttta atttttgagc
    48361 taatttagct acttttctag ctgcagcatt cttatgtata gttcctttag aagctacttg
    48421 gtatattctt ttttgagcgt attggaactt tgcaacagca tcctctctgt ttccagctgc
    48481 aacagcatct tcgaatcttc ttattgcagt ttttatttga gattttctaa ctctatttaa
    48541 agcagttttc ttttcgataa cacttattct tttcttagct gattttatat ttgccaccgt
    48601 gttcacctcc ctgtattttt ttatcatatt catcgtcaac atattagatt ttaacagaaa
    48661 taaatctaaa aatcaaggat tattatttat atattttaat aatgtttttt attttgattt
    48721 tttagactgt aaattgtgta taaataattt gcaatatctt gtttttaaat tggtatattt
    48781 tgtgttttaa atattttgac atatataaat taatatttta tttttgtaac aaatattttg
    48841 aga
//
LOCUS       DAMJWO010000019        46446 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.020, whole genome shotgun sequence.
ACCESSION   DAMJWO010000019 DAMJWO010000000
VERSION     DAMJWO010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46446
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.020"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            523..1851
                     /locus_tag="PC366_001155"
     CDS             523..1851
                     /locus_tag="PC366_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2576690.1"
                     /translation="MGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGDKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIVIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGIKR"
     gene            2606..3439
                     /locus_tag="PC366_001156"
     CDS             2606..3439
                     /locus_tag="PC366_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HDF2576691.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFIVVGVRVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTSIEVSKGPSKSSGKIAYITIDDGPSKFTDEMIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIVQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            3532..4464
                     /locus_tag="PC366_001157"
     CDS             3532..4464
                     /locus_tag="PC366_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2576692.1"
                     /translation="MVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVLSATNNYIN
                     GQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVDSKYQELED
                     KMNLNTSYKEKMDKAGVDKEYLKQEISRDLAIDKNKKAFEDRINISDNDMEAYYTSHK
                     KDFNVEEVSASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESFESLAKKYS
                     DDKATGKNGGQLGYFTKDDKNAEFTKEVFKLKKNEVSNVFETSYGYHIVKVTDKRERQ
                     KSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            4516..4998
                     /locus_tag="PC366_001158"
     CDS             4516..4998
                     /locus_tag="PC366_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2576693.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQEAMY
                     KALYSVENIKEVNYIKTWFYKILVRTSIDFIRKNRKYNNMTDIDLIDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            5010..5879
                     /locus_tag="PC366_001159"
     CDS             5010..5879
                     /locus_tag="PC366_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDF2576694.1"
                     /translation="MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIGVIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKAHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
     gene            5922..6677
                     /locus_tag="PC366_001160"
     CDS             5922..6677
                     /locus_tag="PC366_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDF2576695.1"
                     /translation="MTTYKKLKKSIFKISIFSICLLVSLVDINPIFAGSSSNETSNSD
                     TIKVLNAKSLNFKQGNYEVNVSIPKIKGLKDKTLENKLNNEFLQDGKKIYSEFQNKMK
                     KENNKGHRYLNVIHNVKNNSKDFLSIEMTKEEIEDSSSITKKHYTVDKNRGILLNLPI
                     FFKDSRYIRAISDNIKEQMRNQIKKDDTKSYFIDQDKDFPVKDFESINKYQDFYFNKN
                     GNLVISFEEYEVVPGYMGAVEFVIPNKVIKRLR"
     gene            6719..7540
                     /locus_tag="PC366_001161"
     CDS             6719..7540
                     /locus_tag="PC366_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XdhC family protein"
                     /protein_id="HDF2576696.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANYER
                     FPESEVVVLDSFENIPDFPTDENSYIIILTRGHLYDSSALEWALKRETGYIGMIGSRT
                     KIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            7545..8306
                     /locus_tag="PC366_001162"
     CDS             7545..8306
                     /locus_tag="PC366_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HDF2576697.1"
                     /translation="MNTGSKDIDTLNVNFRGIEIKAVLVYKNRKNISIKIDPFGKIIV
                     MSPPKISKKIIKDIIIEKGDWILKKSEKYKGREEVYKQRMFITGEKFLYLGEEYHLVI
                     KELLKDSVKKSNCRITINEYQIVVQTNDTSTDFIKKSLKSWYKMESERTVLERIDFLK
                     LNCEIMKQLVPASVKVKEQNKRWGSCTAQKNIYINSKISMARLDVIDYVIIHEFSHLV
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKIII"
     misc_binding    8467..8724
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8837..9076
                     /locus_tag="PC366_001163"
     CDS             8837..9076
                     /locus_tag="PC366_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDF2576698.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH"
     gene            9346..10341
                     /gene="ilvC"
                     /locus_tag="PC366_001164"
     CDS             9346..10341
                     /gene="ilvC"
                     /locus_tag="PC366_001164"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HDF2576699.1"
                     /translation="MKMARMYYEKDVDLEVLKNKKVAVLGYGSQGHAHAQNLRDNGVH
                     VVIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPDEKQKKVYEESVKDNLKE
                     GQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVFTKGSGVPALFAVYQDYT
                     KKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVLCGGISELIKLGYKTLVD
                     AGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEYGDYVSGKRVITDAAKQG
                     MQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIAEVGRNLRSMMSFLK"
     gene            10394..12082
                     /gene="ilvB"
                     /locus_tag="PC366_001165"
     CDS             10394..12082
                     /gene="ilvB"
                     /locus_tag="PC366_001165"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HDF2576700.1"
                     /translation="MNGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVP
                     KDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPVIYA
                     GGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLS
                     LLIERVESKNNSNWKEEIKTFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDV
                     GQHQMWSAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKAGNVDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLVNAY
                     NIDGYKVSNMEELGKVLDVIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            complement(12440..13570)
                     /locus_tag="PC366_001166"
     CDS             complement(12440..13570)
                     /locus_tag="PC366_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF2576701.1"
                     /translation="MKGGVRKRSNKWYYYFDLGIVEGKRKKVERVGGNTKKEAEKALR
                     EALNEYENSGIVFEESNISLSDYLDFWYKEYVLLNCKYNTQESYRINIEKHIKPKLGA
                     YKVKALTPAILQNFINKKYKEDYSQNTLQVLKAILHRSLKSAVHPYKHIRENPMQYVS
                     IPKTKSKTETNKVKTITLEEFNQILNIFPQDSFQRIVLLIGFHTGMRRGEIIALKWDN
                     IDLDNKTITVKHTLIKKPNGMFELGQPKTESSCRTIFTGDTLIKALKEHKLYQKKMKL
                     KYGEFYFDSDWVCTKENGQQVNTHTLDTIVRQIRVALNNDFHFHSLRHAHATLLLENG
                     ANIKDIQNRLGHSQLSTTMDTYSHVTDKMKNETVDIFEKITN"
     gene            complement(13649..14356)
                     /locus_tag="PC366_001167"
     CDS             complement(13649..14356)
                     /locus_tag="PC366_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HDF2576702.1"
                     /translation="MSIKNGKDFLYVIWKDPKSRRQFIIGKLAKNGLYEFSYEYEIDE
                     AIKAGFNALISFDDISKTYYSEDLFSPFASRLPDKKRKDINKILDKYDMSEYDTYELL
                     KRSGARLPIDTLEFVDPIPLDIDKNIIRYFYIAGVRHYAGCEGHECDNSIELESNEAL
                     VLELEPENKFDPHAIKVFDKKENHIGYIPRYYSGELTSIINRGLKYNCIIKFVNKENN
                     CDECIKVKLEILFDEYN"
     gene            complement(14369..15238)
                     /locus_tag="PC366_001168"
     CDS             complement(14369..15238)
                     /locus_tag="PC366_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HipA domain-containing protein"
                     /protein_id="HDF2576703.1"
                     /translation="MIKNFDEWKEYDGFSYGSGRSEKIWLINEKTKDIGLFKFPKTKE
                     TGEYWAEKLACEIASLLKIPCANVEIGTYNKRIGSMSYLINKNDEKLIEGVWLINKYY
                     PCYNTDKLYDYKNNEYYSLKMIFKSIEEYNIKNDFLKMLIFDYLIGNRDRHQNNWALL
                     ESQNKITLSPLYDNGSSLCCYVNIENIDSFFTDHQRFEALINTRSRSRIRIDGKNKKE
                     PTHLEVLKYLNSNYYEQTIDFVEKIINLMNEVNINTLIDNYSENIISPKLKKLLKIYL
                     KEKVLRIKNIYNL"
     gene            complement(15858..16364)
                     /locus_tag="PC366_001169"
     CDS             complement(15858..16364)
                     /locus_tag="PC366_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HDF2576704.1"
                     /translation="MNKLDALLDLANNEEIEIYYTDKIADDIKGLYINRQGLKIISLL
                     NSLKQNNAKLIEILAEELGHHFTSVGNYVSSKNSYKNKILIDKTENKALKWACEFLIT
                     EEEIIHVINSHATSVYEIAEELQVSINFLLKRLEFLSKKKSMLDLGNNRFLVLTNLPN
                     FYIYEDIF"
     gene            complement(16440..16988)
                     /locus_tag="PC366_001170"
     CDS             complement(16440..16988)
                     /locus_tag="PC366_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2576705.1"
                     /translation="MLILKKLRTEKGISLDKLSTDLNINKSTLSRIENGLREPKESFI
                     KDCSDYFGVSTDYLIGKINIDDSNKLTKCLNSTFPIRLKELRKKKELTQAELSKLLNC
                     SLSKIAMLETSKREPVKEDLLRISEFFNVSVDYLLGKTSIENYITTDEISKIIKSYES
                     LPKEAQEHINSYIEFLVDRYKK"
     gene            complement(17000..17341)
                     /locus_tag="PC366_001171"
     CDS             complement(17000..17341)
                     /locus_tag="PC366_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDF2576706.1"
                     /translation="MATFGERFKQLREEKKLTQDELVSKFNKVYFTSFNKSTISQYEN
                     NKRKPEINILENWADFFDVSIDYLLGRTLVRNHIDTVAAHRVNPHKDLPEEAQEQLND
                     YIEFLMNKYKK"
     gene            17518..17721
                     /locus_tag="PC366_001172"
     CDS             17518..17721
                     /locus_tag="PC366_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2576707.1"
                     /translation="MKKRSLKAGRIEAGYTQEELAYKIGIAKSTYNLKENGKRNFTEK
                     EMIMISYILNKTMDELFLEKRLT"
     gene            17769..18578
                     /locus_tag="PC366_001173"
     CDS             17769..18578
                     /locus_tag="PC366_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HDF2576708.1"
                     /translation="MNNLQIFKNKTFGEIRVIELNGEFWFVGKDIAEQLGYKDTSDAL
                     KRHVDDEDKGVGEIPTPGGNQNMKVINESGLYSLILSSKLPSAKLFKRWVTNEILPSI
                     RSTGTYNMIDLQTKLPTTYKEALQHLIEQVEVNEQLQLESKMKDQVIKELKPKADYTD
                     MILKNKGLVTITQIAKDYGMSGKEMNKILHERGIQYKQSGQWLLYKQHQGKGYTHSET
                     IDITRSNGMPDVKMTTKWTQKGRLFLYDLLKTNNILPDIEKGYSYQTSILG"
     gene            18625..18834
                     /locus_tag="PC366_001174"
     CDS             18625..18834
                     /locus_tag="PC366_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576709.1"
                     /translation="MENKKIEEIEKRITMLENQLQAQLFSQITAQSNSDFIDYMYQCI
                     VLYLHEMNKSEKRKISEITKERIRK"
     gene            complement(18844..19218)
                     /locus_tag="PC366_001175"
     CDS             complement(18844..19218)
                     /locus_tag="PC366_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576710.1"
                     /translation="MQFSNNISKELQESIRKTVSDTSNTEYFYYAEFQYKIILKSIEE
                     FEKELDDEHEIALKLTNFGKDVLMIVEEVGYHNPCLIHYYGIVNGVYSEILQHTSQIN
                     FMITSVKKTDPSKPARRIGFIL"
     gene            19294..19491
                     /locus_tag="PC366_001176"
     CDS             19294..19491
                     /locus_tag="PC366_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2576711.1"
                     /translation="MLIGDNIKQMLRKRDIKPYKLAKELNIDVSGLYKLLRNKSSNPT
                     IDTLIKLADYLDITLDELVGR"
     gene            19522..19914
                     /locus_tag="PC366_001177"
     CDS             19522..19914
                     /locus_tag="PC366_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2576712.1"
                     /translation="MDISESIAKQFSDSLKSLIEIEISKQETDRVKSQTIEQKVKVLE
                     PKDIVVLIKRGYPNYLITVEEARGILKLDTAFMRRLVSTGLIKSLVRGDGRKISRYEV
                     DDFIERNQGKNLDELLKAVEWGDEIAES"
     gene            19895..20044
                     /locus_tag="PC366_001178"
     CDS             19895..20044
                     /locus_tag="PC366_001178"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576713.1"
                     /translation="MKLLSLDTNNKNVVTLKKDGKVIADIVFKDIKTGKKISVGILNK
                     KVLVK"
     gene            20115..20552
                     /locus_tag="PC366_001179"
     CDS             20115..20552
                     /locus_tag="PC366_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576714.1"
                     /translation="MVEVNVNVKVKVEAPEFTNALLVVANALGGLNLGKAMQIEPINI
                     TDMKEEKKVEVKKAEKIKKVEVKEDVKEEIAEAKEEIEKNNENTTSEVKYTKEEVRTK
                     AAQVSKAGKKDKLKELFGEFGASKLSEVKEEDYSAFMNKLESL"
     gene            20564..21730
                     /locus_tag="PC366_001180"
     CDS             20564..21730
                     /locus_tag="PC366_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HDF2576715.1"
                     /translation="MPLQHARLSASGAHRWLHCTPSIKLEENYPPLTSIYAEEGTVAH
                     ELAEVKLMLEYEKISKKAYNARIKKIQKSEYYNSEMEDYIQSYVENVVELVNDSKAIC
                     DDVIVMLEERLDFSEWVPEGFGTGDVVVISDGILQVIDLKYGKGLEVSAIENPQLRLY
                     GLGAYNQFEMLYDIDLIKTTIIQPRLDNISSEEIEVTKLLTWADNVKKKAQMAFNGEG
                     EFVSGSHCGFCRAKNDCRKRAEDNLKLARKYDFADTFALNKYEIADILGFAKNIQDWL
                     KDVQSYALEQAEKHGVKYPGYKLVEGRSNRKYVDEQEVAKVLLNSDYDEEKIYKPRTL
                     KGISDMEKAIGKKSFAKLLSDLIIKPVGKATLVVESDKRSEINSIDSAKKDFEI"
     gene            21745..22080
                     /locus_tag="PC366_001181"
     CDS             21745..22080
                     /locus_tag="PC366_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576716.1"
                     /translation="MPLDAGIKDKLDESISIILDLKDRKKSIEKDLDYEKDNLLDMLK
                     RLNITEYNSTEENAKVIVMDFKRESLIKDKVMSTFLEVNDNHLDRVYIPEHIKVSPVC
                     FVSVRAKDN"
     gene            22133..22705
                     /locus_tag="PC366_001182"
     CDS             22133..22705
                     /locus_tag="PC366_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase subunit sigma-70"
                     /protein_id="HDF2576717.1"
                     /translation="MSNQEITKLVENNLNLVHFSINRFFKSYVEQHPYLYEEFYQEGC
                     IGLYKAALNYDSNRGKFSTVAVSYIRIEMFKALRYGEKHYRNSIEGLDVSVFEDSKRP
                     LKDIHGFYEIQFNYDVDYIRKIARKSYLKDIDKIVDWILQDKKISDIGELLNVSSTVI
                     CGRIKLFSKQVRDLDKFGEITSNIKSIYQI"
     gene            22728..23300
                     /locus_tag="PC366_001183"
     CDS             22728..23300
                     /locus_tag="PC366_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HDF2576718.1"
                     /translation="MSNSVQSTKVVTGKVRLSYCNIFKSRAMVEGAEPKYSVCILIPK
                     SDKVTLGRIKKAIDAAKEQGKTSKWGGKLPGNLKTPLRDGDAERADEAEEYVGMYFLN
                     ANSTQKPGIVDKDLNEILDNTEVYSGCYGRVSINFFPYNSAGNKGIGCGLQNVQKLAD
                     GEVLGGARASAEADFSDDFEYEDEEEDFLS"
     gene            23300..25258
                     /locus_tag="PC366_001184"
     CDS             23300..25258
                     /locus_tag="PC366_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
                     /protein_id="HDF2576719.1"
                     /translation="MRTLSIDIETYSDLDIKKVGVYRYVDSANFEILLFAYAFDNEEV
                     KVIDLVNDEELPKEVIEALNDNKVIKSAFNANFERTAISKFLNINLKPNEWSCTMIKA
                     LTLGLPGSLDSVSKALKFNEDKQKMKEGKALIQYFCKPCKATKVNKGRTRNLPIHDME
                     KWNKFKEYCKQDVVVEREIRNKLSKYKTTEREIKLWYLDQRINDTGIKVDTELIENAI
                     ECDKRYTEKLTKEAIKITGLNNPNSPAQLKKWLSDKVGFEITSLTKESIPEILKQVDD
                     ENVVRILELRKLMSKTSIKKYEAMKLAKGNDNRVRGLLQFYGANRTGRWAGRLVQVQN
                     LPQNHIEDLDLARNLLKEGDFDLIELLYDSVPDVLSQLIRTAFIPSEGHRFIVSDFSA
                     IEARVIAWFAGEKWRLDVFNSHGKIYEASASHMFKVPIESIKKGDPLRQKGKISELAL
                     GYGGSIGALTSMGAIKMGLDEEELQPLVTTWRNANPNITKFWWDVDKAAKKAIKDRTI
                     VKLQHGIKFIYNPGVLFIELPSGRRLSYLRPKIEPHTTFSGDKITYEGMEQTSKQWKR
                     IDTYGPKLVENIVQATARDCLREAMFNVTDAGYSIVMHVHDELVIDVDKKGGSLEEVN
                     SIMGKEISWAKGLPLKADGYECDYYKKD"
     gene            25270..27687
                     /locus_tag="PC366_001185"
     CDS             25270..27687
                     /locus_tag="PC366_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576720.1"
                     /translation="MDIKASEIEHINVRHDGQLMLAIGKNKLETHWKNKSILWSELVN
                     RLSKTLRTQETYTEYRKMSKTEKDRVKDVGGFVGGSLKNGRRKAENIANRSIITLDID
                     YANKDIWEDITLLNDYACLMYSTHSHTENNPRYRLVIPLTRPVLPEEYQAISRMIADT
                     IGIDMFDDTTYQPHRLMYFPSTSIDGDYIFKFQDGEFLNPNEILDLYLDWTDVSYWPE
                     SSRERQKFNTQLKKQQDPIEKAGIIGAFCRSYSIKETIENFLNEVYIPGIDETRYTYS
                     EGSTSGGVVIYDDKFSYSHHGTDPASGILCNAFDLVRIHKFGELDEDAKPETPVNRLP
                     SFTRMSEFASSDTKVRKTIGRENLDKAKDDFGDIDFEDDEWLTRLDYDNKGSYKKTTN
                     NILMFIENDPYLKGKIAYNEFSNRAVVLGKLPWRKDDKLNDWNDSDDSGLRHHIETIY
                     NISSPSKVNDALIIAFENNTFHPIKDYLNSLKWDGIKRVDTLLIDYLGAEDNHYTRTI
                     IRKVLVAAVARVFNPGIKFDNMMVLSGPQGMGKSTFIKKLGGDWYSDSLTTVQGKEAY
                     EQLQGVWLLEMGEMMATKKADIEAVKHFLSKSEDIYRVAYGKRTSRFLRQCVVIGTTN
                     DKEFLRDKTGNRRFWPIDTGVKKVNKSIFNGQLDNERNQIWAEAVELCKANEQLYLSD
                     EEKKEAERQQRTHSEENAKSGIIEEYLNKPITENWYDLSISEKREYIHGSDFGDLKEG
                     TILREKTCVMEIWVELFNGEPKQLTPILSREINDILKGLDDWISYNGNLRFGKIYGRQ
                     RAYVRKS"
     gene            27969..28295
                     /locus_tag="PC366_001186"
     CDS             27969..28295
                     /locus_tag="PC366_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HDF2576721.1"
                     /translation="MLESKIEKRLKKEIELLGGKAMKFISPGEAGVPDRIVLLPEGHV
                     IFVELKAPGKKLRKLQQYKMRELRELGFKVKCVSTLKEIDDFIKEVKGWNLNHIHTKN
                     TQLEKL"
     gene            28244..29614
                     /locus_tag="PC366_001187"
     CDS             28244..29614
                     /locus_tag="PC366_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2576722.1"
                     /translation="MEFKPHPYQEYTIRKTIDNNNIGLLLDMGLGKTVCTLTAISELM
                     YDYFDISKVLVIAPLRVARDTWSSEVKKWEHLKHLKVSKVLGSKLDRVRALSTDSDIY
                     IINREMVPWIVDFYKRKWPFDMVVIDELSSFKSNKAQRFKSLKKVLPLTKRVVGLTGT
                     PTPNSLIDLWAQMYLLDRGERLGKTITGYKERYFEPGQKNYQTGAIYNWQPKNGAENA
                     IHNKIKDICISLKAEDYLNMPRKIDNKIEIHLDSKILKYYKELEKEKILELDRDIITA
                     SSAAVAANKLLQLANGAIYDNDKNVKELHREKLEALKEIIDVSNGKPIIVFYNYKHDY
                     NRLMKEFKSLKPRTIENSKDIYDWNNGRIQLLLCHPASTGHGLNLQSGGSIIVWFGLT
                     WSLELYQQANARLYRQGQRETVIIHHLICKGTIDEQVMEAIENKDKGQSALLEAVKAK
                     LKEYRE"
     gene            29638..29775
                     /locus_tag="PC366_001188"
     CDS             29638..29775
                     /locus_tag="PC366_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576723.1"
                     /translation="MELISPGKIVRCAWCGRRFYKLDKSKVEYCSRSCSKRARRSDLS
                     G"
     gene            29768..30247
                     /locus_tag="PC366_001189"
     CDS             29768..30247
                     /locus_tag="PC366_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 region 4 domain-containing protein"
                     /protein_id="HDF2576724.1"
                     /translation="MDKESIKEIVRELRKEEREDRKKGVLYNTRLLMKHYNDFKRHID
                     SAVSEAKDVDYLEDDLGKLDNEELYILSIKKSKARTIIMIAHIDSAMKTLKLRQERLH
                     SYEKYRALELYYCDEKTYEEIAEILNCGVVTSRRWINEMVKELGVYLFGIDGLKLTV"
     gene            30530..31079
                     /locus_tag="PC366_001190"
                     /pseudo
     CDS             30530..31079
                     /locus_tag="PC366_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994390.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
     gene            31274..32248
                     /locus_tag="PC366_001191"
     CDS             31274..32248
                     /locus_tag="PC366_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576725.1"
                     /translation="MSNFKKRYIDVYRIDIINKINGSVYSDEEILKEVIKTFFKDKEY
                     CKENKNGINITKDKKFWITEVKCSEDDLIIKVKLEYTKYNQNTNIINAHTKEVEGNKK
                     MDQGDSNKQHLFIKFMKENNIAVVLFERVFVGVPMIELSKNLHLYYEDMIENNKFDNN
                     MSKTSINITQIASKDFIEQILDLDGVSKITLNVDREKFGTDEDNLFSNLNNSRRHNDL
                     IYKPTFRTRYLPSEVKRCCEKYIKGEEFRNKKINRIIIEGEKNKRKLKLDTEGIKLCR
                     EIEVSLDIDNHIDSEDIFEKMNNLIDDLIENNSVFFNLMYQEVAMSEA"
     gene            32269..32778
                     /locus_tag="PC366_001192"
     CDS             32269..32778
                     /locus_tag="PC366_001192"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576726.1"
                     /translation="MYKKVLNILLNYYKAINSKEVVELVLTPVLICIISYMFFNSSIN
                     KEVVISLNKDVLTLSGLLVAFGVCIITLLFTTYNKSISEAKDIKTERKVNGFNISYFQ
                     FIQLKAYYTVIMEILVVVICFINTIMLTRYYSNIIFYVLIFFTVHIILSLTTLIISMF
                     HLSWKDRGD"
     gene            32848..33540
                     /locus_tag="PC366_001193"
     CDS             32848..33540
                     /locus_tag="PC366_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2576727.1"
                     /translation="MQDVKEKVKQDYLKGMKQKEISAKYDISLNTLKSWIKRYNWSSE
                     KKKGAPINKRGAPFSNKNSVGYGAPKENKNAEKFGFFSKYLPEETRELIQEISIKDKF
                     DILWEQITIQYAAIIRAQKIMYVKDKEEMIKELKKHEITENSEKIEYEFQFAWDRQAS
                     FLNAQSRAMSELRSLIKQYDEMIHKDWNLATEEQKTRVEKLKCEVANLNKDDIGDDEL
                     KISVDYGDRNDS"
     gene            33518..34771
                     /locus_tag="PC366_001194"
     CDS             33518..34771
                     /locus_tag="PC366_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HDF2576728.1"
                     /translation="MVIEMIVRINFNPDFKEANFTKKRYRAMKGSAGSGKSVNVAQDY
                     ILKLGDKKYQGANLLVVRKSEATHKYSTYAELTGAINRIYGKQADKYWKTTLNPLEIK
                     SKVTGNSIIFRGVNDAKQREKLKSINFSKGKLTWVWCEEATELMESDIDILDDRLRGI
                     LTNPNLYYQMTFTFNPVSATHWIKRKYFDYKNDDIFTHHSTYLQNRFIDEAYYRRMQM
                     RKEQDPEGYKVYGLGEWGETGGAILKNYVIHEFPTEFEYFDNMRLSQDFGFNHANAIL
                     RIGFKDGELYICNEIYVHEMDTSEIIKIANSRGLEKTLFMYCDSAEPDRIKMWKSAGY
                     KAKGVKKGPGSVKAQIDYLKQLRIHVHPSCTNTIKEIQQWKWKQDERTGLYLDEPVEF
                     MDDAMAALRYSIDNKLKNNGISFLK"
     gene            34777..36219
                     /locus_tag="PC366_001195"
     CDS             34777..36219
                     /locus_tag="PC366_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2576729.1"
                     /translation="MLNIYISETDLIKVQLKKESTFNLVKVIEHYILKHRPEKYKQGE
                     EYYYGNTDVNNKRRYYLLDGAKVDDFTKVNNKAINNYHKLLVDQKVGYSVGNPIVFNA
                     DDDNLTKLLNDLLGEEFDDTITELYLNASNKGVEWLHPYINRKGEFKYVIIPAEEAIP
                     IWDSKRQRELVAFIRFYYIEDIDGNKIKRVEYYTENDVTYFIERGNSFIQEFLYDEYG
                     KMTDIQEGHFRINNKEQGWGKVPFIPFKNNEKCVSDLTFYKSLIDIYDNNISTLADNL
                     DEMQEVIYVLKEYPGTSLQEFIDNIRYYKSIKVDGGGGVDKLEINIPVEAKKELLDRL
                     EKNIIIFGQGVNPESQNTGDKSGVALKFLYSLLDLKCSKTEKKFKKAIRELLWFVCEY
                     LKISGSKSYDYKSVQITFNHSMIINESEKIDMASKSIGIISDETIVSNHPWVEDVNDE
                     LERLKKQEETQKEYDDLIPTNNQEGVIDET"
     gene            36209..37744
                     /locus_tag="PC366_001196"
     CDS             36209..37744
                     /locus_tag="PC366_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HDF2576730.1"
                     /translation="MKHKDYWRKRFEQLEEVQNNKSVKYYLELEKKYKLAMNSIEKDI
                     LSWYNRFAENEGISLLEAKKLLNTRELEEFKWNVEEYIKYGKENAINQKWMKELENAS
                     ARLHITRLEALKLQIQQHVEVLYGNELDGIDKLMRDIYTSGYYHTAFNVQQGVNVGWS
                     LMSLDTNRINKIISKPWATDGLNFSERIWGKHRPTLINELHTKLTQSIIRGENPKNLV
                     NDFAKRFNVSKSQAKNLIMTESAFFASASRKDCFSDLDVEKYEIIATLDLRTSNICRE
                     LDGKIFDMKDYQVGITAPPFHCRCRTTTAPWFEDEEGYRAARGEDGKTYYVPSSMKYN
                     EWYEKHIEGRLGKEKADTLRKMQLNESKDRKQFEEYKKVLGNEIPSKFDEYQHMKYND
                     TIRYEEAKKLYKDVNWQVKNQRNLTSGSVHSVPFESKPNSVFDNYKDGKLIQRRYYGN
                     TGKPRLDLDLTDHRNPKQHKIVPHKHDWLADENNHDKVKREKDMELTKAHKIANKDIL
                     NGE"
     gene            37746..37994
                     /locus_tag="PC366_001197"
     CDS             37746..37994
                     /locus_tag="PC366_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576731.1"
                     /translation="MDNKFKNLQHLIDSIDLGLDIEFDLYNKPYNISIGDDDTRFITL
                     CPNGDTKYYKNGKDMVDNYNIDGKLLKDLWKDIQIVNM"
     gene            38062..38625
                     /locus_tag="PC366_001198"
     CDS             38062..38625
                     /locus_tag="PC366_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HDF2576732.1"
                     /translation="MDWLKELLEGIKVEDNKIDVASLQKSIEKKIKETTVTQEDYVNL
                     ETQLNTANETIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLGDAF
                     KSVKCRDEIALKAHLDMEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGEEPKIDT
                     ITPGQEPKINDFGFNFTGVRPHENNNK"
     gene            38637..39527
                     /locus_tag="PC366_001199"
     CDS             38637..39527
                     /locus_tag="PC366_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HDF2576733.1"
                     /translation="MAALNYAKEYSNVLAQAYPYTLNFGDLYATENNGRYRWTGSKTI
                     EIPTISTTGRVDSNRDTIAVAQRNYDNAWEPKVLTNQRKWSTLVHPADINQTNYVASI
                     GNITKVYNEEQKFPEMDAYCISKIYADWTALGNTADTTVLTTANVLEVFDKLMEKMTE
                     ARVPENGRILYVTPVVNTLIKNAKEIQRTVNIKDGGTSLNRQTTDIDTVKIIKVPSNL
                     MKTAYDFTTGWKVGAGAKQIFMSLVHPSAIITPVSYQFSKLDEPTAVTEGKYFYFEES
                     FEDVFILNKKADAIQFVVEA"
     gene            39546..39779
                     /locus_tag="PC366_001200"
     CDS             39546..39779
                     /locus_tag="PC366_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576734.1"
                     /translation="MPQVKKLNRILTIEECKIDDFLEMGYDLIDETGKAVKYGKSLSV
                     KDLIAENNILRSKVESLEEENKQLKEKNKLTKK"
     gene            39789..40190
                     /locus_tag="PC366_001201"
     CDS             39789..40190
                     /locus_tag="PC366_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576735.1"
                     /translation="MENNIIDEIEKRLESFGYILKDGDKWLIGFVREKIENIIKLDCN
                     IKTMPIELKEIEVDMIVGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLIAYLTTYGKNKILTFRCLRW"
     gene            40184..40531
                     /locus_tag="PC366_001202"
     CDS             40184..40531
                     /locus_tag="PC366_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576736.1"
                     /translation="MVSKTRKAIEMLYRDKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKLAKLEQTIKLFISPDIEIKAGSKLIINDKEYVRSGESAIYPN
                     HQEIILELFKDKA"
     gene            40531..40821
                     /locus_tag="PC366_001203"
     CDS             40531..40821
                     /locus_tag="PC366_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HDF2576737.1"
                     /translation="MARWGSVDFREFKRVCKKMEKFTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLREGWSGVAYARSLPVYKQGNNYIIEVVNPTEYALTQWGI"
     gene            40931..41737
                     /locus_tag="PC366_001204"
     CDS             40931..41737
                     /locus_tag="PC366_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576738.1"
                     /translation="MAKFLDITGKKFGRLRVIKFSKEIKSGKRNRKYWLCKCDCGNFK
                     EIRTDSLTSGLVQSCGCLKKEQDKLNLTDKYQFKKKYKVQNKRLYSIWKGIISRCTDK
                     NNKRYNRYGERNIIVCDEWFCYDNFANWALSNGYSEKLTIDRINNEGNYESSNCRWVD
                     IKTQCRNRSTNILVKHEEKEITLIELSEKTGISYSCLRSRYSKGLVGNKLIEKVKIIE
                     ESRAKLSIEDVKEIRKKYSDGYTIKQLSEIYPVTYSSISNIVHRRTWKNI"
     gene            42086..42523
                     /locus_tag="PC366_001205"
     CDS             42086..42523
                     /locus_tag="PC366_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576739.1"
                     /translation="MLNNIIDGISVKLDKSFGEKYTIYSEDVEQGINEPCFFIVPLNP
                     SKTPYPSGRELKKNSFDVHYFPRSEDKNFEINEIAEMLLEELEYIEIDGDLVRGTNMN
                     FEIIDNVLHFFVDYNYFTIKNNDTNKMDTVELFGGLKRGDNFE"
     gene            42516..42692
                     /locus_tag="PC366_001206"
     CDS             42516..42692
                     /locus_tag="PC366_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576740.1"
                     /translation="MSKALSKEDNYKFTKEQIVNSKKYVNRKDLLNAILKENELYSFS
                     EVEDRINKFMKGVS"
     gene            42693..44003
                     /locus_tag="PC366_001207"
     CDS             42693..44003
                     /locus_tag="PC366_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HDF2576741.1"
                     /translation="MALGGGTFVTQNKILPGAYINFISAKRATSSLSDRGIVAMPLEL
                     DWGIDEEAFQVTSDDFEKYSVKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CTIATAKYSGIRGNDLKVTVTTNIDDNAKFDVVILLDNKKVDTQIAKVITDLQDNDYI
                     TWKKDATLEASAGLVFTGGTNGEAVTGAEYQAFLDKIESYSFNALGCLATTTEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKSDADYEGVVSIENKIKDKDLVESSLIYWATGAIAGC
                     DINKSNTNKKYDGEFDVDVNYTQIQLEEALKTGKFIFHKVGDEVHVLEDINTFVSFTD
                     DKNDDFSSNQSVRVLDQIANDIATLFNEKYLGKVPNDKAGRISFWNDVVKHHKELENI
                     RAIEDFKTDDVSVELGNDKKTVIVSDAIKVINAMSKLYMTVSVN"
     gene            44020..44490
                     /locus_tag="PC366_001208"
     CDS             44020..44490
                     /locus_tag="PC366_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HDF2576742.1"
                     /translation="MAQTINAKDTVSAKKAECFITIEGKRYNFMQAIDLEAKMEKNKS
                     EVPILGRTTKGNKTTGSTNTGSATFHYNTSIFRELLYRYKETGEDIYFDIQVTNEDPT
                     SAVGRQTVVLKDCNMDSGIITKFDADGEYLDEDMDFTFEDWELVESFALLNGML"
     gene            44549..45376
                     /locus_tag="PC366_001209"
     CDS             44549..45376
                     /locus_tag="PC366_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576743.1"
                     /translation="MEFESGIKLGKLTLIKYLGRNKHSKKVWLCQCECGNKVERVENN
                     LKQSIKNEKPPHCGCSPNWKGQNKRFKDITGKTFGKLTVLKMSGKDKYSHNLWLCQCE
                     CGNRTITSTSALEQGKAQSCGCIRKEILLERSTTHNKSNDSLYRVYHRMIKRCTNKSN
                     KDYNYYGGRGIEVCNEWLEDFINFYNWSIENGYRKGLTIDRINVNGNYEPSNCRWVTW
                     EVQRNNKRNSIRVNYKGEMITLKQCAENLNVKYLFLYNQLVTKKIPLEEVIKNIGME"
     gene            45448..45888
                     /locus_tag="PC366_001210"
     CDS             45448..45888
                     /locus_tag="PC366_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDF2576744.1"
                     /translation="MSNLSAFLSQNAIKVDNVKYVASNRFLDKEGKPVEWELKVLSSE
                     EDEALRRKCTKRVKVIGNNGKHTGQYTSEIDYNSYVAELCVASTVFPDLKDAELQNSY
                     GVMGEAQLLKTMLTAGEYVNYTVKVNEVNGFDTSFEDKVEEAKN"
     gene            46229..46390
                     /locus_tag="PC366_001211"
     CDS             46229..46390
                     /locus_tag="PC366_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576745.1"
                     /translation="MNNFLLNVIAGVIASLIFCLICKVFLKVKSHSTRGKSKSGWEFD
                     FKIKFHKFK"
BASE COUNT        18758 a         4805 c         8330 g        14553 t
ORIGIN      
        1 catctaaaag gaattttcaa acctaatatt tcatttttaa ataaaaaaat aaaatattag
       61 ttttgattta tggtttaaat tgggttataa taaattgtca aattatttat taatataaaa
      121 tagactataa aacaagcaaa aatcatacta ttatataaaa gaccttaaag atagaaaatt
      181 acagaaagaa gccaaaatgt ttttgaaaaa aatgaaattt tattgcaaaa aaatcaaaat
      241 caatttaact taatagttat aatctatttt tagtgttaca aatatacaat gtatattata
      301 caatataaaa aatacgttta tttataaata ttattatatt tggatttttg gtttttataa
      361 tttttttata tttaaacata actaaaagta aaagattacg aaagctaagt agagtttatt
      421 ttattttaat aaataaaaaa gctatttttc tatatattgg cataatatat gcttatttaa
      481 ctatgaaatt aaaattaaat aggattaatg aggaggaaaa gaatgggaag taatgaactg
      541 aaaaagactc ttggcgtatc agcagcatta tcaactgttg ttggttctgt tataggagcg
      601 ggcgtatttt ttaaaccaca agcagtctat acattaactg gaggagctcc aggtcttggt
      661 atattggcat ggttaatagc tggaatcata actataacag ctggtcttac agctgcagaa
      721 gtatcagttg cgataccaaa aactggtgga atgatggtat atataaaaga aatttatgga
      781 gacaaattag gttttttaac tggatggatg caaattgtat tattttatcc agggatgatg
      841 gcagcattag gtgttatatt tggagaacaa gcatcagcac taattggtag cccatcactt
      901 ttacttccaa tagcaattgg aattatagta atagttgcag ggcttaatat gttaggttca
      961 aaaactggag gagtcataca aactgtctct acaatttgta agttaatacc acttatttta
     1021 ataatggttg ttggatttat taaaggtggt ggaaataatc caatacttac acctatggtt
     1081 ggtgaaggat taagcctggg tagtgtacta ggtcaagttt taattgctat attatttgct
     1141 tttgatggat ggatgaatgt tggtacttta gctggagaaa tgaagaatcc tggaaaagac
     1201 cttccaaaag ctataatagg tggattgtca gttgttatgg ctgtttattt tataataaat
     1261 ttagcgtatc tttgggtatt accagctaat gaattagcaa attatgcttc tcctgcatca
     1321 gcagttgctg aagttatatt tggttcaatg ggtggaaaaa taatatctgt aggtatatta
     1381 atttcagtgt ttggagcatt aaatggattt ttactaactg gttcaagggt ggcatatact
     1441 ttagctacag ataagacttt accaaagtat ggtatatttt ctaaattaaa ttctgctcaa
     1501 gttccagcaa atgcaatagc attagtatct gttattgcat ctatatatgc tttgtcaggt
     1561 caatttaatt tattaactga cttagctgta tttgctactt ggatattcta tgtattaact
     1621 tttatagggg ttatgaaact tagaaagact catccaaata taccaagaga gtataaagtt
     1681 ccattatatc ctattgttcc tataatagct atagcaagtg gtatatttgt tgtagttaat
     1741 caattgtgtt ttgcagggat gaaaactact atgatatcta taggaggtct tgtaataaca
     1801 gctataggct taccagtgta tgcttatatg actagaggaa taaaaagata aaccaagtag
     1861 tttacaaatg ctttataatt aaaataaaag agactgtctc aaaatagaga taagtctctt
     1921 ttttattgtt aaaagggtaa agagatgttt tattttataa aaaaagagtg ttctatgaac
     1981 taaaaagttt attttaaggt attcacttta tttttagttt ttgaattata aaattaaaca
     2041 tctaaaaaat tatttgcttt aagatacttt attttaaagt gttttttttt caaactaagt
     2101 gatatctata taacaaatat tatacatagg ttttatgaaa attaaatctt tctgttatat
     2161 aaaatagaat attgtattat atagaaaata ttacctgatc aatatcgtga tttataaata
     2221 agattagaaa attttatttg ataacaaaaa ttagacaata tgaatatata atgtatgtat
     2281 taaaaatgtg gcaaatagtt gttttggtat ttattatttg tttaatattt ctaatttata
     2341 aaaaaaaaat tataaatttt aaaaattata aatgacattt taactagaat taattgtaaa
     2401 aaacactata taatactcaa ttttcaacat tctatacaat tatacagaaa ttatacagca
     2461 taataatcac cgaaataaca aattttaaaa attaagcaaa actttttgtc gaagttcaac
     2521 gtctatatat atgtagtgta aatttttggg ataaaatact acaaaaatat aaatgtaaaa
     2581 atatagtaat attggaggtc gaacgatgag aaataaaaag aaaaaaataa atagaaagaa
     2641 gttgtatttg cttttaagtg ctattgtagt gtgtctggct tttatagtag ttggtgttcg
     2701 cgtcagctct ttaaatatga aggaaaatga aattagtaga aatgcaaaac tgtcaagttc
     2761 tactattaca gatatagtat ctaatacatc aatagaagtt agtaaagggc caagtaaaag
     2821 ttctggaaaa atagcataca taactataga tgatggccca tctaaattta ctgacgagat
     2881 gataaaaact ttaaataaat acaatgttaa agcaactttt tttatgatag atgggaatat
     2941 gaaggaatat ccacagcaag ttaaaaatat aattaaaaat gggaacacag caggttttca
     3001 tagtgtatca catgatattc acaagcttta tgttactagt acatcagcaa aagaggaatt
     3061 tgatacaaat gatcaaactt tttataagat aactggtaaa cattcaaaag taataagaat
     3121 accttatgga agcaaaccat atacaccaca agcctcttat caggctttag ttgatgctgg
     3181 atataaaatt tgggactggg acttagatac agaagattgg agatctaatt cttctcaaat
     3241 tgtacaaaat gtaaaaaatc atattaagaa tagaaaaggt gaagataaag accaacttgt
     3301 agttttaatg catgagaaaa aacagagtgc agaagcttta gattcagttt taaaattctt
     3361 atcagatgaa ggttatgaat ttgcgccagt agatcaaaac caaataccaa aaaattattg
     3421 gttacgtaat ttagagtagt taaaatataa gaatattgat tgatattttt agaaattgag
     3481 aataaaaatg agtgaggtgt aggtatattg aataaaaaac tttatatagg aatggtcgga
     3541 atattgtctt tgatgatggt tggttgtaat aaaagtttag caaaagtaaa tgatgtggaa
     3601 atcacaaaag aacagtacaa aaaaacaaaa gcagttttat ctgctactaa taattatata
     3661 aatgggcagt ctttagatga attagaaaaa actttggata aaaaaggtag aaataaatta
     3721 gaaaatgtta taatatcgtt tatggtggat aatgaacttt tatatcaaga ggctaaggat
     3781 aaaggactaa ctccaagtaa aagtgaagta gactcaaaat atcaagaact agaagataag
     3841 atgaatttga atacaagcta taaggaaaaa atggacaaag caggtgttga taaagaatat
     3901 ttaaaacaag aaatatctag agatttagca atagataaaa ataaaaaggc ctttgaagat
     3961 agaataaaca taagtgataa tgatatggaa gcctactata caagtcataa aaaagatttt
     4021 aatgtagaag aagtaagtgc ttctcagata cttatatcga ctttagataa aaataaaaaa
     4081 gaagtaagca aagataaaaa agaagctttg aagaagaagg cagataatat attgactaaa
     4141 atcaaaaatg gagaaagttt tgaaagttta gctaaaaaat attcggatga taaagcaact
     4201 ggaaaaaatg gaggacagct aggatatttt acaaaggatg ataaaaatgc tgagtttaca
     4261 aaggaagtgt tcaaattaaa gaaaaatgaa gtttcaaatg tgtttgaaac tagttatgga
     4321 tatcatatag tcaaagttac tgataaaaga gaaagacaaa aaagttttaa tgagtgtcag
     4381 agtttaataa gagaatctat tttaaatgaa aagtatattg agcatataaa aaaactgaat
     4441 gaagatgcta aaatagacag atagaatttc taacagctca atcctagcct gtaatcggag
     4501 ggagatttta caggaatgtt taagagttta aagagaacga aagttgagaa atacattatc
     4561 gataataaag actcttttta tagaatagca tatagttata cgaagaatga agaagatgcc
     4621 ttagatgtgg ttcaagaagc catgtataag gcactatact cagtggaaaa tattaaagaa
     4681 gtaaattata taaagacatg gttttataaa attttagtta gaacgagtat agattttatt
     4741 agaaaaaacc gtaaatataa taatatgaca gatattgacc ttatagatga gactggagag
     4801 tatgataaat atactgattt ggatttaaga agagctttgg aagaattacc tattgaatac
     4861 aaatctatta taatattaag attttttgaa gatttaaaga ttgaagaagt agcaataata
     4921 ttggatgaaa atgtgaatac tgttaaaact aggttatata ctgctttaaa aaaactaaaa
     4981 ttaaaaattg aagagtaggg ataaaaagaa tgacaagcaa agaaaggtta aataagttaa
     5041 aagatgagta tcataaaatt ccaataccca agaaattaga tactataata aatcatgaaa
     5101 aaatagaaaa catatatcga gagaaaaata aaaaagtaaa tagattaaga tttaaagttg
     5161 caatagcctt tgcatgtata tttacagtat tagtaaatat aagtcctgta tttgcagaca
     5221 atttttctaa gatacctgta attggagtaa tagtagaagt aataactata aaaaattata
     5281 gtttaaaaag tgaaaattat gaagctgaga ttgatattcc taaaatacga ggtttaaaag
     5341 ataaaaactt agaacaaaga ttaaacagta gttttatgga agatggaaaa aggctttatc
     5401 atcaattcca agagagaatg gagaagatac aatcatcaaa gaataaagga tataaatctt
     5461 taagtttgag ttatagtgta aaaaataatt ctaaaaaatt tctatcaata gagatgacaa
     5521 aaaatgagat agaggcttca tcatatgtga gtaaggcaca ttatactatt gataaaaaaa
     5581 gacaaatagt tttgactttg ccaatgcttt ttaaagatga taagtatata aaagttataa
     5641 gtgataatat aaaagaacaa atgagagaac aaatgaaaaa ggatagtaca aaatcctatt
     5701 ttatagatca aaaaaaagac ttgcctgttg aagattttaa aacaattaat aagtatcagg
     5761 atttttattt taataaaaat gaagaccttg taatttgttt tgatgaatat gaagtagcac
     5821 ctggttatat gggtgcagtt gagtttgtaa taccatataa agtaataaaa gatttgtaaa
     5881 ttgaatagta gtttatatat acatatttta agaaggacaa tatgactaca tataaaaagc
     5941 ttaaaaaatc tatatttaaa atttctatat tttcaatatg cttattagtc tcattagtag
     6001 atataaaccc tatatttgca ggtagttcct ctaatgagac ttcaaatagt gatacgataa
     6061 aggtgttaaa tgctaagagt ctcaacttta aacaaggcaa ttatgaagtg aatgtgagta
     6121 ttcctaaaat aaaaggttta aaagataaaa ctttagagaa taaattaaac aatgagtttt
     6181 tgcaagatgg gaaaaaaatt tacagtgaat ttcaaaataa aatgaaaaag gaaaataata
     6241 agggtcatag atacctaaat gtaatccata atgtcaaaaa taattctaag gactttttat
     6301 caatagaaat gacaaaagaa gagatagaag attcctcgtc tataactaag aagcattaca
     6361 ctgttgataa aaatagagga atactattaa atttaccaat attttttaaa gatagtagat
     6421 atattagagc tataagtgat aatataaaag agcagatgag aaatcaaatt aagaaagatg
     6481 atacaaaatc ttattttata gaccaagata aagacttccc agtgaaagat tttgaatcta
     6541 taaataagta tcaagatttt tattttaata aaaatggaaa tcttgtgatt agttttgaag
     6601 aatatgaagt agtacctggt tatatgggag cagtagaatt tgtgatacca aataaagtaa
     6661 taaaaagact aagatagata tatagaagat ttttagatag actggtaagg agaattatat
     6721 gaatatatat gaacaagcaa taagattaat agaaaataat gaagatttcg catttgctac
     6781 aataacgtct cattcaggtt caacaccacg tgaaactgga gcaatgatga ttgtgaaaaa
     6841 tgattctact atatttggtt cagtaggagg aggtagtgta gaagcagaat gtataaaaca
     6901 tgcaattaat gttataaaaa atagagaatc aatgttgtat aaatttactc taaacaaatc
     6961 tgatgtggca aaactaggaa tgatatgtgg aggtactgga gaaatacaaa tagattttat
     7021 agatagtaaa ttaaaaagta atatagaaaa attcaataag agactaaagg aaaatacaag
     7081 taaagcatat atatttggtg caggtcatat ttcaagagat gttgctgtga tactatctct
     7141 tttagaattt agaacagtag taatagatga tagagaagaa tttgctaatt atgaaaggtt
     7201 cccagaatca gaagtagtag ttttagattc ttttgaaaat ataccagatt ttccaactga
     7261 cgaaaatagc tatataatta ttttaacaag aggtcatcta tatgattcaa gtgctttaga
     7321 atgggctctt aaaagagaaa ctggttatat aggtatgatt ggaagtagaa caaaaattgg
     7381 attgacgtac gaaaaactca tgaaaaaagg ttttaagaag gaagaattat caaaagtaca
     7441 tgcaccaata ggcataaaat tgaatgctca aacaccagct gaaatagctg tatgtatagc
     7501 tgctgaactt ataaattgta gagctaataa ggaaaaataa actaatgaac acagggagta
     7561 aagatattga tactttaaat gttaatttta gagggattga aataaaagca gttttagtat
     7621 ataaaaatag aaaaaatatt tctataaaaa tagatccatt tggcaaaata attgtaatga
     7681 gtcctcctaa aatatccaaa aaaataataa aagatataat tattgaaaaa ggagactgga
     7741 tacttaaaaa gtcagaaaaa tataaaggaa gagaagaagt atacaaacaa agaatgttta
     7801 taactggcga aaaatttctt tatttaggtg aagagtacca tctagttata aaagaactgt
     7861 tgaaagattc tgtcaaaaaa agtaactgta gaataactat taacgaatat caaatagttg
     7921 ttcagacaaa tgatacaagt acagatttta ttaaaaaatc tttaaaatct tggtataaga
     7981 tggaaagtga aagaacagta ttagagagaa tagattttct taaattaaat tgtgaaataa
     8041 tgaagcaatt agttccagca agtgttaagg taaaagaaca aaataagaga tggggaagtt
     8101 gtacagctca aaaaaatatt tatataaact caaaaatatc tatggcaaga ttagatgtaa
     8161 ttgattatgt aataatacat gagtttagcc atttagtaca tatgaatcac tctaaaaaat
     8221 tctatgattt agtaaaatcc attatgcccg attataaaga taaagaaaat tggctaaaaa
     8281 taaatggata taaaataata atctgaaaac gattattcca aaatacaggc gtaaagtata
     8341 aaagaagtat tattgtgaaa aaaataaata atctgaaaat tttaaaaaaa gtcattgaca
     8401 ttgtaaatga tagggaatat aatctatatt aacaacaaaa cagaattaaa atataaaatt
     8461 aaaaaattaa aagcaatgac agagacaaca atactaatag tgttatccac agagaaccaa
     8521 tgttgctgag aattggtgtt aacagtagta taatgatcac tctggagctt ttgtactgaa
     8581 tatttttagt aagtacaaac gtatgtcaac gttacatgac taaggttaag gtaattaatt
     8641 acccgacctg aaaaaagagg ggtagatgta ttttttatat ctacaaataa ggtggtaccg
     8701 cggaatataa ctttcgtcct tataagtaat atttatattg cttataaaga tgaaagtttt
     8761 tttattttaa gcgatataaa taaatttaat ccatataaaa ttaataaaaa aataataaaa
     8821 ataaggaggg atttttatgg aaaatactgt atatgctaaa ttaaaccaag gaatagattc
     8881 ttttttaaga gtggctatga ctctaagaag aagagaggtt gatatacaat caataagtat
     8941 gactgtagat aatatgaata attcaggtat aaaattaata gtaaatgaag aaaagacatc
     9001 tttagattct gtcttaaacc atatgaaaaa actacatgat ataagagaga taactgttga
     9061 aagaatgaga cattaattaa atatatttta taaagctaaa gataaatatt aaataagaaa
     9121 aatcttagat taaaatataa gtgtcattga atttatcagt ttatcacagt taataaattt
     9181 attagtttgt tgtagctaat aaaaactgaa aattctaaaa ttataattgt aagattatat
     9241 aaatttagaa tttaaatctg ttgaataata ttaaaacaat gataatgagt atgaatttct
     9301 aataaaaata aatatcataa aaataagaaa aagtattggg aggaaatgaa aatggcaaga
     9361 atgtattatg aaaaagatgt ggatttagag gttttaaaaa ataaaaaggt tgcagtttta
     9421 ggttatggaa gtcaaggaca tgcacatgca caaaatctta gagataacgg tgtacatgta
     9481 gtgataggtc tttatgacgg aagtaaatca gcacaaaaag caaaagaaga tggatttgaa
     9541 gttaagagtg tagcagaagc tacaaaagaa agtgatttga caatgatgtt aatgcctgat
     9601 gaaaaacaaa agaaagttta tgaagagagt gtaaaggata acttaaaaga aggtcagaca
     9661 ttagcttttg ctcatggatt caatatacat tataatcaag tacaaccacc agaatttgtt
     9721 gatgttgtaa tggtagctcc taaaggacct ggtcacttag ttagaaatgt atttacaaag
     9781 ggaagtggag ttcctgcact atttgcagta tatcaagact acactaaaaa agctacagag
     9841 acagttttag catatgcaaa agggatagga gcaacaagag caggtgtttt agaaactact
     9901 tttaaagaag aaacagaaac agatttattt ggagaacaat cagtactttg tggtggaata
     9961 agtgaactta taaaattggg atataaaacg cttgtagatg caggttatca aaaagaagta
    10021 gcatactttg aatgtttaca tgaaatgaaa ctaatagtcg accttatata tgaaggtgga
    10081 tttgaaagaa tgagatatag tataagtgac acagcagaat atggagatta tgtatctggt
    10141 aaaagggtaa taactgatgc tgcaaaacaa ggtatgcaaa atgttttaga ggatatacaa
    10201 aatggaaaat ttgcaaaagc gtggattaaa gaaaatgaag aaggacgtga aaacttccta
    10261 aaaactagag aagaagaata taatacagaa attgccgaag ttggtagaaa tctaagaagt
    10321 atgatgtcat tcttaaaata aatatatatt aaatggatta gtttgaggga aagagtggtg
    10381 tatagtagtg cgtatgaatg gagcaaaggt aattttagaa tgtttaaaga aagagggaat
    10441 tgacacaata tttggatatc ctggtggagc cgtgatacct ctttatgatg ctctatacga
    10501 ttattcagat gattttaaac atataaggac atcccatgaa caaggtttag ttcatgctgc
    10561 agatgggtac gcaagaagta ctaatacagt aggagtttgt tttacaacat ctggtccagg
    10621 agcaacaaat gccataactg gaatagcaac agcttttatg gattcttcac ctatggttgt
    10681 aatttcaggg caggtgccaa ctagtttatt aggaaaagat tcttttcaag aaattgacat
    10741 aactggagca acattatcta tgacaaaaca taattattta gttagaaaca ctaaagaatt
    10801 agttcctaca ataaaagaag cttttagagt tgcaaattca ggtagaaaag gacctgtact
    10861 tgtagatgtt ccaaaagatt tatttttagc agaaatggat tttagtggtg aggactatga
    10921 tttatgtcaa atagatgatt atatggatta taagagtgat tttgatctag atgatgaaac
    10981 taatattaag cttttaaatg aagcaataga tatcataaaa gaatctaaaa agcctgtaat
    11041 atatgcaggt ggaggtgtta aatcttcaga cagtgaggaa attcttgaaa aatttgcaac
    11101 taagatagat acacccgtac taaatacact tatggggctt ggaaatatag atagaaagaa
    11161 tgaactatct cttggaatgg ttggaatgca tggaagtaga gaaagtaatt tagcactttc
    11221 taattcagat ttagtaatag cgataggtgc gagatttagt gatagagtga taagtaaaag
    11281 ttctgaattt gctaaaaatg caaaaataat acacatagac atagacccat ctgaaataag
    11341 taaaaatata gaatctaatg tatctttggt tggagatgta aagctagtcc ttagtttatt
    11401 aattgaaagg gttgaaagta agaataatag caattggaaa gaagagataa agacatttag
    11461 aaagagtgag ggtgtacaaa catatgaatt tcatccacaa aatatactta aaaaaataaa
    11521 tgaaaaatat gaaacattaa agaaacccac tgtggtagta actgatgtcg gtcaacatca
    11581 aatgtggtct gctaaatact ggaattttaa aggtaataaa agttttataa catcagcagg
    11641 gttaggaact atgggatttg gtttaggtgc agctattgga actaaagctg gtaatgtaga
    11701 taaaaatgtg gttttagtaa ctggtgatgg aagttttaga atgaactgta atgaactagc
    11761 tacagttgca aattataatg tacctatgct tattttacta ctcaataata gaacattagg
    11821 aatggtaaga caatggcaga agttattttc caatcaaaga tactctcaaa ctgatattaa
    11881 tgaaaatgtg gattatgtta aactcgtaaa tgcatataat attgatggat ataaggtatc
    11941 caatatggaa gaattaggaa aggttctaga tgtgatagat tttaataaac ctgtattttt
    12001 acaatgtgat atagataagg attatgatgt ttatcctatt gtagcaccta atgatgcatt
    12061 ggaaaatttg atatgtaact aaaacttata ctgaatattg ataaaatttt ttattaaatt
    12121 tttattggta ttcagttttt gtttagagat agattggcat tttttatttt tgcaaataaa
    12181 tcaatgaata tataattaag aacttattaa attttaatta tacaatttag aatagtatta
    12241 caacttaagt aaatattaag ttttattcgt tagatttatt attaatacct tatattagtt
    12301 atggttgtta tatactctaa agccttgaaa ttacaagcgt atagctgact atataaattt
    12361 gataatttta gcttttaaaa tagataaatt agattttgcc acccatttgc caccgtatta
    12421 tatttttggg tggcaaactc taatttgtaa ttttttcaaa tatatctaca gtttcatttt
    12481 tcattttatc agttacatgt gaataggtat ccattgtagt tgataattgg ctatgaccca
    12541 aacggttttg tatgtcttta atgttagcac cattttctaa taatagagta gcatgtgcat
    12601 gtcttaaaga atgaaaatgg aagtcattgt ttaaagctac tcgaatttgt cttactatag
    12661 tgtctaaagt gtgagtattc acttgttgac cattttcttt ggtacatacc caatcactat
    12721 caaagtaaaa ttctccgtat tttaatttca ttttcttttg atataattta tgttctttta
    12781 atgcctttat taaagtgtca cctgtaaata tagttctgca agagctttct gtttttggtt
    12841 gccctaattc aaacattcca tttggttttt taatcaaagt atgctttact gtgatagttt
    12901 tattatcaag gtctatatta tcccatttta gtgcaataat ttcacctctt cgcataccag
    12961 tatgaaatcc aattagtaaa actatacgtt gaaatgaatc ttgaggaaat atatttagta
    13021 tttgattaaa ttcttctaat gtaatagttt taactttatt agtttctgtt ttagatttag
    13081 tttttggtat gcttacatat tgcatagggt tttctcgtat gtgtttgtaa ggatggactg
    13141 ctgattttaa tgacctatgt aatatggctt ttaatacttg taatgtattt tgagaataat
    13201 cctctttgta ctttttattt atgaagtttt gtagtattgc aggagttaaa gcttttactt
    13261 tgtaagctcc tagttttggc tttatatgtt tttctatgtt tattcggtag ctttcttgag
    13321 tgttgtattt acagttgagt aaaacatatt ctttgtacca aaagtctagg tagtctgata
    13381 agctgatgtt actttcttca aagactatgc cagagttttc atattcattt agtgcttctc
    13441 ttagtgcttt ttctgcttct ttttttgtat tgccaccaac tctttctact ttttttcttt
    13501 ttccttctac tatgcctagg tcaaagtagt aataccattt gttgcttctt tttcttactc
    13561 cacctttcat aatagtatcc ctccctttta gaatgtatgt ttgtttggtg tttatataaa
    13621 aaatgtctcc tatatttaca agaagacatt aattatattc gtcaaataat atttctaatt
    13681 taacttttat acattcatca caattatttt ctttgttaac aaatttaata atgcaattat
    13741 actttaatcc tctatttatt atacttgtta attctccact ataatatcta ggaatgtaac
    13801 ctatatgatt ctctttttta tcaaatacct tgattgcatg aggatcaaat ttattttctg
    13861 gttctaactc tagaactaga gcttcatttg attctaattc tattgaatta tcacattcat
    13921 gtccttcaca cccagcataa tgtcttactc ctgcaatata aaaatatcta attatatttt
    13981 tatcaatgtc caaaggaatt ggatctacaa attctagtgt atctataggt aatcttgcac
    14041 cacttctttt taaaagttca tatgtatcat actcagacat atcatactta tccaaaattt
    14101 tattgatgtc ctttcttttt ttatcaggta atctacttgc aaatgggcta aataaatctt
    14161 cactataata tgttttacta atatcatcaa atgatattaa agcattaaaa cctgctttaa
    14221 tagcttcatc aatttcatat tcataagaaa attcatacaa tccattttta gctaactttc
    14281 caattataaa ttgtcttcta ctttttggat ctttccaaat aacatataaa aaatcttttc
    14341 catttttaat tgacatttta tccctctttc acaaattata tatatttttt attcttaaca
    14401 ctttttcttt tagatatatt tttagcaatt tttttaactt tgggcttata atattttctg
    14461 aatagttatc tattaatgta tttatgttta cttcattcat aagatttatt atcttttcta
    14521 caaaatctat agtttgttca taataatttg aatttaaata ttttagcact tctaagtgtg
    14581 ttggttcttt tttatttttt ccatctatcc ttattcttga tcttgaacgt gtatttataa
    14641 gagcttcaaa tctttgatga tcagtgaaga aagaatctat gttctcaata ttaacataac
    14701 aacataatga tgatccgtta tcatatagag gactaagagt aattttattt tgactttcta
    14761 gtagagccca attattttga tgcctatctc tatttccaat caagtaatca aaaattaaca
    14821 tttttagaaa atcatttttt atgttatatt cttctataga tttaaaaatc attttcaatg
    14881 aatagtattc attattttta taatcatata acttatctgt attataacaa ggataatatt
    14941 tgtttattaa ccacacgcct tcaatcaatt tctcatcatt tttattgatt aaataactca
    15001 ttgaaccaat tcttttatta tatgtaccta tctcaacatt agcacaagga atctttaaca
    15061 aactagctat ttcacaggct aatttttctg cccaatattc tccagtttct tttgttttag
    15121 ggaatttaaa caagcctata tctttagttt tttcattaat tagccagatt ttctcgcttc
    15181 ttccactacc ataagaaaaa ccatcatact ctttccattc atcaaaattt ttaatcacga
    15241 aaataatcct ctcaaacaag tattttatat tcttattgta tcatttgatt ctaaatttgc
    15301 aagaatttta ttatccataa taagcttaac ttaaaataaa aattttttct agattttatt
    15361 tattccactt ttaacttcaa gctttattac atatggaata tgtgtttact catcaaaatt
    15421 actactgtgt ataatggttt tactttataa atacttaatt ttagttttct atatttattt
    15481 ggtaattttt ttgagtgttg ttaagtaaga aatatttttt gtaccaaaag gtaagctgat
    15541 attgctttat tcagatacta tgcctaggtc aaagtagtaa taccatttgt tgcttctttt
    15601 tcttactcca cctttcataa tagtatctct cccttttaga atgtatgtat gtttggtgtt
    15661 tatataaaag agcagattaa ctgctcttta tatacttttg ttatgtacaa tattatctta
    15721 attttgttta tctggttttt acttaattat tttcttaata ttcttacaat tttttagctt
    15781 ttatgtgtag tttattataa taatattgaa atatatattt attaagtaaa aaatctataa
    15841 aagtagaata aatgagttta aaaaatatcc tcatatatgt agaaatttgg caaattagtt
    15901 aatactaaaa atctattatt tcctaagtcc aacatgcttt tcttttttga tagaaattct
    15961 aatcttttta gtaagaagtt gatgctaact tgtaattctt cagctatttc gtatacactt
    16021 gtagcgtgtg aattaataac atgtattatt tcttcttctg ttataagaaa ttcacatgcc
    16081 cattttagtg ctttgttttc agttttgtct atcaagattt tatttttgta actgtttttt
    16141 gaagatacat agtttccaac actggtaaaa tgatgtccta attcttctgc taagatttct
    16201 attagtttag cattgttttg ttttaatgaa ttaagtaatg atataatttt tagtccttgt
    16261 ctgtttatat acaatccttt tatgtcatct gctattttgt cagtgtagta aatttctatc
    16321 tcttcattat ttgctaagtc taaaagtgcg tctagtttgt tcattgaaat ccccctataa
    16381 aaagaatgta tgtgttactt ttttatatat aaagagcagg agtgaactgc tctaaatatt
    16441 cattttttat atctatcaac taaaaactct atgtagctat taatatgttc ttgcgcttct
    16501 ttaggtaaac tttcataaga tttaattatt ttggatattt catcagtagt tatgtaattt
    16561 tcaattgagg ttttaccaag tagataatca actgacacat taaaaaattc tgaaattctt
    16621 aacaagtctt ctttaacagg ttctcttttg ctagtttcta acatagcaat tttgcttagt
    16681 gaacaattaa gtaattttga taattctgct tgagttaatt cttttttctt tcttaattct
    16741 tttaacctta ttggaaaagt tgaatttaag cattttgtta atttatttga atcatctatg
    16801 ttaatttttc caattaagta atctgtagat actccaaaat agtctgagca atctttaata
    16861 aatgattctt ttggttctct taacccattt tcaattctgg ataaagtgga tttatttata
    16921 tttaagtctg tgcttaattt atctaaagaa attccttttt cagttctcaa tttttttaat
    16981 attaacatag attcaatcct tattttttat atttattcat taaaaattca atataatcgt
    17041 tgagttgttc ttgagcttcc tctggtaaat ctttgtgagg attaactctg tgtgcggcta
    17101 cagtatcgat gtgatttcta acaagagttc tacccaaaag ataatcaatt gatacatcaa
    17161 aaaaatctgc ccaattttct agaatattta tttctggttt tcttttatta ttttcatatt
    17221 gcgatattgt tgatttatta aaacttgtaa agtaaacttt attgaatttt gaaactagtt
    17281 catcttgagt aagttttttc tcttctcgta attgtttgaa acgttctcca aaagttgcca
    17341 caaacaacac ctcccaataa ttaaatgata ctataagttt acagaaacgt aaacttatgt
    17401 ttagaaaaaa ataaaaaagt taacaaaaaa ataaacttat gtattgacaa gttttgtttg
    17461 tgtgaatata ataaaagtat gaagttcaca aaaataaaac attggaaggt gaagaacatg
    17521 aagaaaagaa gtttaaaagc tggtcgaata gaagcaggat atacccaaga agaactagca
    17581 tataagatag gaatagcaaa atcaacatat aatctaaaag aaaatggaaa aagaaatttt
    17641 acggaaaaag aaatgataat gattagctat attttaaata aaacaatgga tgaacttttt
    17701 ttagaaaaaa ggttaacata aattaaaatt tattgttcac aaaaacaatc ataaggagga
    17761 aagaaattat gaataattta caaatattca aaaataagac ttttggagaa ataagagtaa
    17821 tcgaactaaa tggagaattt tggtttgttg gaaaagatat tgcagaacaa ttaggatata
    17881 aagatacatc tgatgctttg aaaagacatg ttgatgatga agataaagga gtaggtgaaa
    17941 taccgactcc tggtggtaat caaaatatga aagtaattaa tgaaagtggt ctttattctt
    18001 taatattaag ttctaagttg ccaagtgcaa aattatttaa acgttgggta actaatgaga
    18061 tattaccaag tatacgtagt actgggacat ataatatgat agatttgcaa actaaactac
    18121 caactacata taaagaagcg ttacaacatc ttatagagca agtagaagta aatgagcagt
    18181 tacaactaga aagtaaaatg aaagaccaag taataaaaga actaaaacca aaggcagatt
    18241 atacagatat gatattaaaa aataaaggac ttgtcacaat aactcaaata gcaaaagact
    18301 atggaatgag tggaaaagaa atgaataaaa tacttcatga aagagggatt caatataaac
    18361 aaagtggaca atggctttta tataaacaac atcaagggaa gggatacact cattcagaaa
    18421 caatagacat aactagaagt aatggaatgc ctgatgtaaa aatgacaact aagtggactc
    18481 aaaagggaag attgttttta tatgatttat tgaaaacaaa taacatatta ccagatatag
    18541 aaaaaggata tagttatcaa acttcaatat taggttagta ctttgaaaac taaatacaga
    18601 atattttaga aaggagagat tgaattggaa aataagaaaa tagaagaaat agagaaaaga
    18661 ataaccatgc ttgaaaatca attgcaagca cagttattta gtcagataac agctcaatca
    18721 aatagtgatt ttatagatta tatgtaccaa tgtatagttt tgtatttaca tgagatgaat
    18781 aaaagtgaaa aaagaaaaat tagtgaaatt actaaagaaa gaatcagaaa ataagaatga
    18841 taattacaat ataaaaccta ttcttctagc aggttttgaa gggtcagttt tctttactga
    18901 agttatcata aagtttatct gtgatgtgtg ttgaagaatt tcagaataaa ctccatttac
    18961 tatgccgtag tagtgaatta gacaagggtt atgataacct acttcttcaa caatcattaa
    19021 gacatctttt ccaaagttag tcaattttag tgcaatttca tgttcatcat caagttcttt
    19081 ttcaaattcc tctatagatt taagaataat tttatattga aattcagcat agtaaaaata
    19141 ctctgtgtta gaagtatcag agactgtctt tcttatactt tcttgtaatt ctttagatat
    19201 attgtttgaa aactgcataa tacaccatcc ttttgaaaat tttggaattt attccatgtt
    19261 tatattatac catgtagaac tgaggtgaat acaatgttaa taggcgacaa tataaagcaa
    19321 atgctaagaa aaagagatat aaaaccttat aaattggcaa aagaattgaa tatagatgta
    19381 agtggtttat ataaattact gagaaataaa agttctaatc caactataga tactctaata
    19441 aaattagctg attatttaga tattacatta gacgaattag ttggaagata aataattaaa
    19501 aagaggggag agaattttca catggatatt tctgagagta tagcaaaaca atttagtgat
    19561 agtttaaaaa gtttaataga aatagagata agtaaacaag agacagatag agttaagagt
    19621 caaactattg aacaaaaggt aaaggtactg gagcctaaag atatagttgt tttaataaaa
    19681 agaggttatc caaattatct aataacagta gaagaagcaa ggggaatttt aaagttagat
    19741 acagctttta tgcgtaggtt agtaagcaca ggtttgataa aatcactagt tagaggtgat
    19801 ggtagaaaaa tttcaagata tgaagttgat gattttattg aaagaaatca aggtaaaaat
    19861 ttggatgaac ttttaaaagc agtagagtgg ggggatgaaa ttgctgagtc ttgatactaa
    19921 taataagaat gtagtaactc ttaaaaaaga tggaaaagtt atagcagata tagtatttaa
    19981 agatattaaa actggtaaga aaatatcggt tggaatatta aataaaaaag tgttggtaaa
    20041 ataaccaaca cacaaaaaaa taaaaaataa aatataacac aagtaaagta taacacaaaa
    20101 aggagatatt taaaatggtt gaagttaatg taaatgtaaa agttaaagta gaagcaccag
    20161 aatttacaaa tgcactatta gtagtggcga atgctttagg aggtcttaat ctaggaaaag
    20221 caatgcagat agaacctata aatataacag atatgaaaga agagaagaaa gttgaagtta
    20281 aaaaagctga aaagattaaa aaggtagaag taaaagaaga cgttaaagaa gaaatagcag
    20341 aagcaaagga agaaatagaa aagaataatg aaaatacaac tagtgaagtt aaatacacaa
    20401 aagaagaggt aagaactaag gcagcacaag taagtaaggc aggtaagaag gataagctta
    20461 aggagttatt tggtgaattt ggagctagta agttaagtga agtaaaagaa gaagattatt
    20521 cagcttttat gaacaaatta gaaagtttat agggggtaca taaatgccat tacaacatgc
    20581 aagacttagt gcgagtggag cccatagatg gcttcactgc actcctagta taaaattaga
    20641 agaaaactat ccaccattaa ctagtatata tgcagaagaa ggaacagttg cacatgaatt
    20701 agcagaagtt aaattaatgc tagagtatga aaaaataagt aaaaaggcat ataatgcaag
    20761 aattaaaaag atacagaaaa gtgagtatta taactctgaa atggaggact atatacaatc
    20821 ttatgttgag aatgtagttg aattagtaaa tgatagtaaa gctatatgtg atgatgtaat
    20881 agtgatgtta gaagaaagac tcgattttag tgagtgggtt ccagaaggat ttggaacagg
    20941 agacgttgtt gtaatatctg atggtatact tcaagttata gacctaaagt atggaaaagg
    21001 tttagaagtt tcagctatag agaatcctca acttagacta tatggtttag gggcatataa
    21061 tcagtttgaa atgctatacg atattgattt aattaaaaca acaataattc aacctagact
    21121 tgataacata tcaagtgaag aaatagaagt tactaaatta cttacatggg cagataatgt
    21181 taagaagaag gctcaaatgg cttttaatgg tgaaggagag tttgtaagtg gcagtcattg
    21241 tggattttgt agagctaaaa atgattgcag aaaaagagct gaggataacc ttaaactagc
    21301 tagaaaatat gattttgctg acacatttgc tcttaataaa tatgagatag cagatatttt
    21361 aggttttgct aagaatatac aagattggtt aaaggatgtt caaagttatg cactagaaca
    21421 agctgaaaag catggtgtta aatatccagg atataagctt gtagaaggca gaagtaatag
    21481 aaagtatgta gatgagcaag aagttgctaa ggttttatta aattcagatt atgatgaaga
    21541 aaaaatttat aagccaagga ccttaaaagg aattagtgat atggagaaag ctataggtaa
    21601 aaagagtttt gctaaactac taagtgattt aattataaaa ccagttggaa aagctacttt
    21661 agtagtagaa agtgataaaa ggtcagaaat taatagtata gattcagcga aaaaagattt
    21721 tgaaatataa atgggggata ttacatgcca ttagatgcag gtataaaaga taaattagat
    21781 gaaagcataa gtataatttt agatttaaag gatagaaaaa agagtatcga aaaagattta
    21841 gattatgaaa aagataattt actagatatg ttaaagagac taaatattac agaatataac
    21901 tcaactgaag aaaatgcaaa agttatagtg atggatttta aaagagaaag tttaataaag
    21961 gataaagtga tgtcaacttt cctcgaagta aatgacaatc atcttgatag agtgtatata
    22021 ccagaacata taaaagttag tccagtatgc tttgtatcag taagagcaaa ggataattaa
    22081 aaatatttaa ttcctagtag ctataaaaag atttaaaagg ggatataatt ttatgagtaa
    22141 tcaagaaata actaaactag ttgaaaataa tttgaatctt gtacatttta gtataaatag
    22201 attttttaag tcttatgtag agcaacatcc atacttatat gaagagtttt atcaagaagg
    22261 atgtattggg ttatataaag cagcattaaa ttatgatagt aacagaggca agttttctac
    22321 agtggctgtt tcttacataa gaatagaaat gtttaaagct ttgcgttatg gcgaaaaaca
    22381 ttatagaaac tctatagaag gtttagatgt aagtgtattt gaagatagta aaagaccatt
    22441 aaaagatata catggatttt atgaaattca atttaactat gatgttgatt atataagaaa
    22501 aattgcaaga aagtcatatt taaaagatat tgataaaata gtagattgga ttttacaaga
    22561 taaaaagata tctgatatag gagagttatt aaatgtttct tcaacagtta tttgtggaag
    22621 aattaaattg tttagtaagc aagttagaga tttagataaa tttggagaaa taacttcaaa
    22681 tataaaatca atataccaaa tataaaaata ttaggaggaa gaaaattatg agtaattcag
    22741 tacaatcaac aaaggtagta acaggaaagg taagattaag ttattgcaat atctttaaaa
    22801 gcagagcaat ggtagaaggt gcagagccca agtattcagt ttgtatttta ataccaaaat
    22861 cagataaggt gactttagga agaataaaga aggctattga tgcagctaaa gaacaaggta
    22921 aaacttctaa atggggtgga aaattaccag gtaatttaaa aacacctctt cgtgatggag
    22981 atgcagaaag agctgatgaa gcagaggaat atgtaggaat gtatttttta aatgcaaata
    23041 gtacacaaaa gccaggaata gttgataaag acttaaatga aatattagat aatacagagg
    23101 tatatagtgg ttgttatgga agagttagta taaacttttt cccatataat agtgcaggaa
    23161 ataaaggaat aggttgtggc ttacaaaatg ttcaaaagtt agcagatgga gaagtacttg
    23221 gaggagctag agctagtgca gaagcagatt tctcagatga ctttgaatat gaagatgaag
    23281 aagaggactt cttaagttaa tgaggacctt atcaattgat atagaaacat atagtgattt
    23341 agatataaaa aaagttggag tctacagata tgtagactct gctaattttg agatactgtt
    23401 atttgcctat gcttttgata atgaagaggt aaaagttatt gatttagtaa atgatgaaga
    23461 gttaccaaaa gaagtaatag aagctttaaa tgataataaa gttataaaat cagcatttaa
    23521 tgctaatttt gaaagaacag caataagtaa atttttaaat attaatttaa aaccaaatga
    23581 gtggtcatgt acaatgataa aggcgttaac actaggactt ccaggaagtt tagatagtgt
    23641 gtctaaggct ttaaagttta atgaagataa acagaaaatg aaagaaggta aagcattaat
    23701 acaatatttc tgtaaacctt gtaaggctac aaaagttaac aagggaagaa ctagaaattt
    23761 accaatacat gatatggaaa aatggaataa atttaaagaa tattgtaaac aagatgttgt
    23821 agttgaaaga gaaataagaa acaaacttag taagtataag actaccgaaa gagaaattaa
    23881 attatggtat ttagaccaga gaattaatga tactggtatt aaagttgata cagagttaat
    23941 agagaatgca atagaatgtg ataaaagata tactgaaaaa cttacaaaag aagcaattaa
    24001 aataactggt ctaaataatc caaatagtcc agctcaatta aaaaaatggt taagtgataa
    24061 agttggcttt gagattacaa gcctaacaaa agaaagtatt ccagaaatat taaaacaagt
    24121 tgatgatgaa aatgtagtta gaattttaga acttagaaaa ttaatgtcca aaacttctat
    24181 aaagaaatat gaggctatga aattagctaa aggtaatgac aatagagtaa gaggtctact
    24241 acagttttat ggggctaata ggactggtag atgggcagga agattagtac aagtacagaa
    24301 tttaccacaa aatcatatag aggatttaga cctagctaga aacctattaa aagaaggaga
    24361 ttttgattta atagagcttt tatatgatag tgtaccagat gtcttaagtc aattgataag
    24421 gacagctttt ataccaagtg aaggtcatag atttatagta tcagatttta gtgcaataga
    24481 agctagggtt atagcttggt tcgctggtga gaagtggaga ttagatgtat ttaattctca
    24541 cgggaaaata tatgaagcta gtgctagtca tatgtttaaa gttccaatag aaagtattaa
    24601 aaaaggtgac ccacttagac aaaaaggtaa gatttcagag ctagctcttg gatatggggg
    24661 aagcatagga gctttaacat caatgggggc tataaaaatg ggtcttgatg aagaggagct
    24721 tcaacctctt gtaacaacat ggagaaatgc taatccaaat ataactaaat tttggtggga
    24781 tgtagataag gcagctaaaa aagccataaa agataggact atagtaaaac tccaacatgg
    24841 gattaaattt atttataatc caggagtttt atttatagaa ctaccaagtg gtagaagatt
    24901 atcatatcta agacctaaga tagagcctca tactacattt agtggggata agataacata
    24961 tgaaggtatg gaacagacaa gtaaacaatg gaaaagaata gatacttatg gacctaagtt
    25021 agttgagaat attgttcaag ctacagctag agattgctta agagaggcta tgtttaatgt
    25081 gacagatgca ggttatagca ttgtaatgca tgtacatgat gagcttgtaa ttgatgtaga
    25141 taaaaaagga ggttctttag aagaagttaa cagtattatg ggaaaagaaa tatcttgggc
    25201 taaaggtctt cctcttaaag cagatggata tgaatgtgat tattataaga aagactaggt
    25261 gattgattta tggatataaa ggccagtgaa attgaacaca taaatgtaag acatgatggc
    25321 caactcatgc tggccatagg aaaaaataaa ttagaaacac attggaaaaa taaaagtatt
    25381 ttatggtccg aacttgtaaa tagattaagt aaaacattaa gaactcaaga aacatataca
    25441 gaatatagga agatgtcaaa gactgaaaaa gatagagtta aagatgttgg tggatttgta
    25501 ggtggaagct taaaaaatgg aagacgaaaa gcagagaata ttgcaaatag aagtattata
    25561 actttagata tagattatgc gaataaagat atatgggagg atataacatt attaaatgat
    25621 tatgcttgtc ttatgtattc tacgcactca catactgaga ataatcccag atatagactt
    25681 gtaatacctt taactagacc agtactacca gaagaatatc aagcaatttc caggatgata
    25741 gcagatacta taggaataga tatgtttgat gatactacat atcaacctca tagacttatg
    25801 tattttccaa gtacttcaat tgatggagac tatatattta aatttcaaga tggagagttt
    25861 ttaaacccaa atgaaatact agatttatat ttagactgga cagatgtaag ctattggcca
    25921 gaaagttcga gggagaggca aaagtttaat acacaattaa aaaaacaaca agaccctatt
    25981 gaaaaggctg gaattatagg tgcattttgc aggtcctata gtataaaaga aactatagaa
    26041 aatttcttaa atgaagtata tattcctggt attgatgaaa ccaggtatac atattcagaa
    26101 ggtagtacaa gtggtggagt agttatttat gatgacaagt tttcatatag tcatcatggt
    26161 acagacccag caagcggaat tttatgcaat gcttttgatt tagttaggat acataaattt
    26221 ggtgaacttg atgaagatgc taaacccgaa acgcctgtaa atagattacc ttcatttact
    26281 cgaatgagcg aatttgcaag cagtgacact aaagtacgaa agactatagg aagagaaaac
    26341 cttgataaag ctaaggatga ttttggtgat atagattttg aagatgatga atggttaact
    26401 aggttagatt atgacaataa gggaagttat aagaaaacaa caaacaatat cttaatgttt
    26461 atagaaaatg acccatattt gaaaggaaaa atagcttata atgaattttc aaatagagct
    26521 gtcgttttag gtaagttacc ttggagaaaa gatgataaat taaatgattg gaatgatagt
    26581 gatgattctg ggcttagaca tcatatagaa acaatttaca atatctcatc accatcaaaa
    26641 gtaaatgatg ctctaataat tgcttttgaa aataatactt ttcatcctat aaaagattat
    26701 ttaaattctt taaagtggga tggcattaag agagtggata cacttttaat tgactattta
    26761 ggtgcagaag ataaccacta tacaaggact ataataagaa aagttttagt agcagcagta
    26821 gcaagagtat ttaatccagg aataaagttt gataatatga tggttttatc tggtcctcaa
    26881 ggaatgggaa aaagtacttt tattaaaaaa cttggtggag actggtattc tgatagttta
    26941 actactgtac aaggtaaaga agcgtatgaa caattacaag gagtatggtt gctggaaatg
    27001 ggtgaaatga tggctactaa aaaagcagat attgaggcag ttaagcattt tctaagcaaa
    27061 tcagaggata tatatagggt cgcatatggg aagagaacat caaggttttt acgtcaatgt
    27121 gtagttatag gaacaactaa tgataaagaa tttttaagag ataagaccgg gaatagaagg
    27181 ttttggccaa tagatacagg agtaaagaag gttaacaaga gtatatttaa tggtcaactt
    27241 gataatgaaa gaaatcaaat ttgggcagaa gcagtagaat tatgtaaagc caatgaacag
    27301 ctatatctat cagatgagga gaaaaaagaa gctgaaagac aacaaagaac tcactcagaa
    27361 gaaaatgcta aatctggaat tatcgaagag tatctaaata aacctattac tgagaattgg
    27421 tatgatttaa gtatttcaga aaagagagaa tatattcatg gttcagattt tggtgattta
    27481 aaagaaggaa caatattaag agaaaaaacg tgtgttatgg agatatgggt tgagctattt
    27541 aatggagaac ctaaacaact cacgcctatc ttatcaagag aaattaatga tatattaaaa
    27601 ggattagatg attggatatc atataatgga aatttaaggt ttgggaaaat atatggtagg
    27661 cagagagctt atgtacgtaa aagttagtgt caacagaatt aaaaacagag taaatttgaa
    27721 aattttaaaa gtgtcaacaa tgtcaacaaa aaaaatggct ttgttgacgc ttatgttgac
    27781 acctaagatg cagtaattac aatgtttgag gtattaatgt caacaatgtc aacaaaaatt
    27841 aagtataaag tagtataagt aatattaggc atatacgtat atacatatgt atgcctaata
    27901 tgtatatata catatatata gaaaatctgt tgacattgtt gacacttaaa ttttaaggaa
    27961 gtgatatttt gttagaatca aaaatagaaa aaagacttaa aaaagagatt gagttgttag
    28021 gtggaaaggc tatgaagttt atttcaccag gtgaggcagg tgtgccagat aggattgtct
    28081 tattaccaga aggacatgtt atatttgtag aacttaaagc accaggtaaa aaactaagga
    28141 agcttcaaca atataaaatg cgagaattaa gagaattagg atttaaagtt aagtgtgtaa
    28201 gcacattaaa agagatagat gattttatca aggaggttaa gggatggaat ttaaaccaca
    28261 tccataccaa gaatacacaa ttagaaaaac tatagataat aataatatag gtttactatt
    28321 agatatggga ttaggtaaaa cagtctgtac tctaacagct ataagtgaat taatgtatga
    28381 ttactttgat atatcaaaag ttttagttat agcaccttta agagttgcaa gagatacctg
    28441 gagtagtgaa gtaaaaaaat gggaacatct aaagcatcta aaagtatcta aagttcttgg
    28501 tagtaaatta gatagagtga gagctttaag tacagactca gatatttata taataaatag
    28561 agaaatggta ccctggatag tggattttta taaaagaaaa tggccatttg atatggttgt
    28621 gatagatgaa cttagttctt ttaaatcaaa taaagcacaa cgatttaaaa gtttaaagaa
    28681 agtattgcct ttaactaaaa gagtagttgg gcttactggt acaccaacac caaatagttt
    28741 aatagactta tgggcacaga tgtacttact tgatagaggt gaaagactag gtaaaactat
    28801 tacaggatat aaagaacgat actttgagcc aggacaaaaa aattatcaaa caggagctat
    28861 atataattgg caacctaaaa atggagcaga aaatgcaata cataataaaa taaaagatat
    28921 ttgtataagc ttaaaagcag aagattattt gaatatgcct agaaaaatag ataataaaat
    28981 tgaaatacac cttgatagta aaatacttaa atattacaaa gaattagaaa aagagaagat
    29041 attagaatta gatagagata taataacagc ttcatcagca gctgtagcag caaataaact
    29101 tttacaatta gctaatggag caatttatga taatgataaa aatgtaaagg aactccatag
    29161 agaaaaatta gaagctttaa aagaaattat agatgtttca aatggtaagc ctattatagt
    29221 tttttataac tataaacatg attataatcg tttaatgaaa gagtttaaga gtttgaaacc
    29281 aagaacaata gaaaactcaa aagatatata tgattggaat aatggaagaa tacaattatt
    29341 actttgtcat ccagcaagta caggacatgg acttaattta caatcaggtg gaagtataat
    29401 tgtttggttt ggattaactt ggagcttaga actgtatcaa caagctaatg caaggcttta
    29461 tagacagggt caaagggaaa ctgttattat ccatcatcta atctgtaaag gtacaataga
    29521 tgaacaagta atggaagcta tagagaataa ggataaaggg caaagtgcat tacttgaagc
    29581 agtaaaagca aaattaaaag aatataggga gtgaaggtat gaaagtaaaa agaaaagatg
    29641 gaacttataa gcccaggtaa aatagtaaga tgtgcttggt gtggtagaag attttataag
    29701 ttggataaat ctaaagttga gtattgcagt agaagttgtt cgaagagagc aagaaggagt
    29761 gatttaagtg gataaagaaa gtataaaaga aattgtaaga gagttaagaa aagaagaaag
    29821 agaagatagg aaaaaaggcg ttttatataa tactagatta ttgatgaagc attataatga
    29881 ttttaagaga catatagact cagcggtaag tgaagctaaa gatgtagatt acttagagga
    29941 tgatttaggt aagcttgata atgaagagtt gtatatttta agtataaaga aaagtaaagc
    30001 aagaactatt attatgatag cacatataga ttcagcaatg aaaactttga aattaagaca
    30061 agagcgttta cattcttatg aaaagtatag agctttagag ctttactatt gtgatgaaaa
    30121 aacatatgaa gaaatagcag agatattaaa ttgtggagta gttacatcaa gacgttggat
    30181 taatgaaatg gtaaaagaac ttggagtgta tttatttggt atagatggct tgaaattaac
    30241 tgtttgataa atacatgata aaaagatgat attttaatga tatttaaccc ctgttataat
    30301 ggtagtatga aacaagtgta taatatattc ccccttgaaa aaggctaagt taccccaact
    30361 tagtcttttt tattttgtaa ataaggagaa tgataaatga gtaattcatg acttagagtg
    30421 atttctaggt ctttttttat acaattttaa tctctcatat tgaagggtcg aaaataaggg
    30481 tgttcaaatt gaatattctt tattaataac taatttagga ggtagtagta tgttgaaaat
    30541 tttacaagag aaaaatgtaa ggatgatatg gtcaaaaaat ggagaagaag tttggtttaa
    30601 tgcaaatgac gtaggagagg aactaggcat agtaaatatt cgtgatacat taagaaatat
    30661 agatagagaa tataaaaaga aatttaatga gtctactgtc ggagattcct acactagaaa
    30721 ctttaaagat aaattgccta actttggtac tacttttgtt acagaagaag ctgtgtacaa
    30781 tatgtcattt agaagtaata aagcagaagc aaaactattt acgaagtggg ttacaaaagc
    30841 acttaaacaa attagaatac atggttacta tattgccaca gaaaaagatc aagaatggct
    30901 ggatataaga acagaaggta aaaggtcaga aaagatttta cagatgaaat acaagagttt
    30961 ttttattaat acaagtactt gaaagagtta tatctatgaa attacctagg ttgatagata
    31021 aaggtatgaa ttataaagag gtatataaaa agattaaaga attaatcgaa atgatttaaa
    31081 tgactgtatt aatagagggt cttttttttt atgtaatgaa ttaaaaatga aatatatttg
    31141 tacattatag acaggaataa ggtaaaagta ttatttagac ttattttgtg gttgtcgaat
    31201 gattattgaa ggatattgac tgattatata gaattatatc attataaata tttgtgaaag
    31261 gaataatggt ataatgagta attttaaaaa aagatatatt gatgtttata gaatagatat
    31321 tataaataaa attaatggga gtgtctattc agatgaagaa attttaaaag aggtaataaa
    31381 gaccttcttt aaggataaag aatattgtaa agaaaacaaa aatggaatta atattactaa
    31441 agataaaaag ttttggatta cagaagtaaa atgtagcgag gatgatttaa taatcaaggt
    31501 gaaacttgaa tatactaaat acaatcagaa tacaaatatt ataaatgctc atactaaaga
    31561 agtagagggt aataaaaaaa tggatcaagg agatagcaat aagcagcacc tatttattaa
    31621 atttatgaag gaaaataata tagcagtagt attatttgaa agagtttttg tgggggttcc
    31681 catgattgaa ctaagtaaaa acttacatct atattatgag gatatgattg aaaataataa
    31741 atttgataat aatatgtcaa aaacatcaat taatattaca caaatagcaa gtaaagattt
    31801 tatagaacaa atattagatt tagatggtgt ttcaaaaata actttaaatg ttgatagaga
    31861 gaagtttgga actgatgaag ataatttgtt ttctaattta aataattcaa gacgacataa
    31921 cgatttgata tataagccca catttagaac tagatattta cctagtgaag ttaaaagatg
    31981 ttgcgaaaaa tatattaaag gagaggaatt tagaaataaa aaaataaata ggataataat
    32041 tgagggagag aaaaataaga gaaaattaaa gttggatact gagggtataa agttgtgtag
    32101 agaaatagag gtttctcttg atatagataa tcatatagat agtgaagaca tttttgagaa
    32161 gatgaataat ttgatagatg atttaattga gaataattca gtttttttta atttaatgta
    32221 tcaagaagtt gctatgagtg aagcatagat tgctaaggag gtgttaaaat gtataaaaag
    32281 gtattaaata tcttactcaa ttattacaag gctataaatt ctaaagaagt agtagagtta
    32341 gttttaacac cagtattaat atgtattatt tcatacatgt tttttaattc gtcaattaat
    32401 aaagaagttg taatttcttt aaacaaagat gtactaactt tgtcaggact attagtagct
    32461 tttggagttt gcattattac attattgttt actacatata acaaatcaat atcagaagca
    32521 aaagatataa aaacagaaag aaaggtaaat ggatttaata tatcatactt tcaattcata
    32581 cagttaaaag catattatac tgtaataatg gagattttgg ttgttgtaat atgttttatc
    32641 aatacaataa tgcttactcg atattattct aatataattt tctatgtttt aatatttttt
    32701 acagttcata taattttatc tctaactaca ttaataataa gtatgtttca tttatcctgg
    32761 aaggatagag gagactagat ttgaaacaat cctattaaat aggattgttt ttttattccc
    32821 aaaacaaaca aataaagagg tggtgatgtg caagatgtca aagaaaaggt aaaacaagat
    32881 tacttaaaag gaatgaaaca aaaggaaata tcagcaaagt atgacattag tttaaatact
    32941 ttaaagtcat ggataaaaag atacaattgg tctagtgaaa aaaagaaggg tgcacctata
    33001 aataaaaggg gtgcaccctt ttctaataaa aattcagttg gttatggtgc tccaaaagag
    33061 aataaaaatg ctgaaaagtt tggtttcttc tcaaaatact tacctgaaga aactagggaa
    33121 ttaatacaag aaatatctat aaaagataaa tttgatattc tttgggaaca gataacaatt
    33181 caatacgcag caataataag agcacagaag ataatgtatg ttaaagataa agaggaaatg
    33241 attaaggaat taaagaaaca tgaaatcaca gaaaatagtg agaagataga gtatgaattt
    33301 caatttgcat gggataggca agcatctttt cttaatgcac agagtagagc tatgagtgag
    33361 ttaaggagtt taattaagca gtatgatgaa atgattcata aggattggaa tttggctaca
    33421 gaggagcaga aaacaagagt tgagaagttg aaatgtgagg ttgctaacct aaataaagat
    33481 gatattggag atgatgagtt gaaaataagt gtagattatg gtgatagaaa tgatagttag
    33541 aataaatttt aatccagatt tcaaggaagc taattttact aaaaaaagat acagagcaat
    33601 gaaaggttca gcagggagtg gaaaatctgt taatgtagca caagactata tactaaagtt
    33661 aggagataag aagtatcaag gagctaatct attagtagtt agaaagtcag aagctacaca
    33721 taagtattca acgtatgcag agcttacagg agctataaat cgtatttatg gtaaacaagc
    33781 tgataagtat tggaaaacta ctttaaatcc tttagaaatt aagagtaaag ttactggtaa
    33841 ctctataatt ttcagaggag ttaatgatgc aaaacaaaga gaaaaattaa aatcaattaa
    33901 cttctcgaaa ggaaaattaa catgggtttg gtgtgaagaa gctacagaac ttatggaaag
    33961 tgacatagat atactagatg accgtttaag aggtatttta actaatccta acttgtatta
    34021 tcaaatgaca tttacattta atccagtctc agctactcat tggataaaaa gaaagtattt
    34081 tgactataaa aatgatgata tatttactca tcatagtact tatctacaaa atagattcat
    34141 agatgaagct tactacagaa gaatgcaaat gagaaaagag caagacccag aagggtacaa
    34201 agtatatggt cttggagaat ggggagaaac tggtggagca atacttaaaa attatgttat
    34261 acatgaattt cccacagaat ttgaatactt tgacaatatg agactgtcac aagactttgg
    34321 ctttaatcat gcaaatgcaa tacttagaat tggctttaag gatggagagt tatatatatg
    34381 taatgaaata tatgtacatg aaatggatac ctcagaaatc ataaaaattg caaatagtag
    34441 aggtttagaa aagactctat ttatgtactg tgatagtgct gaaccagata gaattaagat
    34501 gtggaagagt gcaggatata aagctaaagg agttaaaaaa ggaccaggaa gtgttaaagc
    34561 tcaaatagat tatttgaaac aattaagaat acatgtacat cctagttgca ctaataccat
    34621 aaaagaaata caacaatgga aatggaaaca agacgaaaga actggattat atcttgatga
    34681 accagttgag tttatggatg atgcaatggc tgctcttaga tattctatag ataataagct
    34741 taaaaataat ggaataagct tcttaaagta aaggaggtgt taaatattta tataagtgaa
    34801 acagatttaa taaaagttca gttaaaaaaa gagagcacct ttaacctagt aaaagtcata
    34861 gaacactaca tcttaaagca taggccagaa aaatataaac aaggagaaga atactattat
    34921 ggtaatactg atgtaaacaa taagagaaga tattatctct tagatggagc taaggttgat
    34981 gattttacta aagttaataa taaagcaatt aacaactacc ataagctttt agttgaccaa
    35041 aaggtaggct atagtgtcgg aaatcccata gtatttaatg cagatgatga taatctcact
    35101 aagcttttaa atgacttact aggagaagag tttgacgata caataacaga actatatctc
    35161 aatgctagta ataaaggggt tgaatggtta catccatata ttaatagaaa aggtgagttt
    35221 aaatatgtaa taattccagc tgaagaagca attcctattt gggatagtaa aagacagagg
    35281 gaattagttg catttattag gttttattat attgaagata tagatggaaa taaaataaaa
    35341 agagttgagt actacacaga aaatgacgta acttacttta ttgaaagagg taatagtttt
    35401 attcaagaat ttttatatga tgaatatgga aaaatgactg atatacaaga aggtcatttt
    35461 agaataaata acaaagaaca gggatggggt aaagttccat ttataccttt taaaaataat
    35521 gaaaagtgtg tctcagattt aactttctat aagtctttaa ttgatatata tgataataac
    35581 atttctacac ttgcagacaa tttagatgaa atgcaagagg tcatttatgt attaaaagag
    35641 tatccaggaa caagtctaca agagtttata gataatataa gatactataa atcaattaaa
    35701 gtagatggtg gaggtggagt tgataaacta gagataaata taccagttga agccaaaaag
    35761 gagcttcttg atagattaga aaagaatata attatttttg gtcaaggagt taatcccgaa
    35821 tctcaaaaca caggtgacaa atcgggtgta gctcttaaat ttttatattc actacttgat
    35881 ttaaaatgtt ccaagactga aaagaagttt aaaaaagcaa ttagagagct tttatggttt
    35941 gtgtgtgagt atttaaagat aagtggtagt aagagctatg attataagtc agttcaaata
    36001 acatttaatc attctatgat aataaatgag tctgaaaaaa tagatatggc ttctaaatca
    36061 attggaatta tatcagatga aactattgtt agtaatcatc cttgggttga agatgttaat
    36121 gacgaacttg aaagacttaa aaaacaggaa gaaacccaaa aagaatatga tgatttaatt
    36181 cctactaata atcaagaggg tgttatagat gaaacataaa gattattgga ggaaaagatt
    36241 tgaacaatta gaagaagttc aaaacaataa aagtgtaaaa tattatcttg aattggaaaa
    36301 gaaatacaaa ttagctatga atagtataga aaaagatata ttatcatggt ataacagatt
    36361 tgctgaaaat gaaggaatat ctttattaga agctaagaaa ctgttaaata caagagaatt
    36421 agaagaattt aagtggaatg tagaagagta tattaaatat ggcaaagaaa atgctataaa
    36481 tcaaaagtgg atgaaggagt tagaaaatgc tagtgcaaga cttcatataa caaggcttga
    36541 agctttaaag ttacaaatac agcaacacgt agaagtttta tatggaaatg aacttgatgg
    36601 tattgataaa ctaatgagag atatttatac aagtggatac tatcatacag cttttaatgt
    36661 tcaacaagga gtaaacgttg gttggagttt aatgagtctt gatactaata gaataaataa
    36721 aattatctct aaaccatggg caacagatgg attaaacttt agtgaaagaa tttggggtaa
    36781 gcatagacct actttaataa atgaactaca tactaagcta actcaatcaa ttattagagg
    36841 tgaaaatcca aaaaatctag taaatgactt tgctaagaga tttaatgtat ctaaatcaca
    36901 agctaagaat ttgataatga ctgaatcagc tttctttgca tcagcaagta gaaaagattg
    36961 ttttagtgat ttagatgtag agaaatatga gattattgct acattagatt taagaacttc
    37021 aaatatatgc agagagttag atggaaaaat atttgatatg aaagattatc aagttggaat
    37081 aacagctcca ccatttcatt gtcgttgtag gacaacaaca gctccttggt tcgaggatga
    37141 agaaggctat agagcagcaa gaggagaaga tggaaaaaca tattatgtac catctagtat
    37201 gaagtataat gagtggtatg agaaacatat agagggtaga cttggaaaag aaaaagctga
    37261 cacccttaga aaaatgcaac taaatgagag taaagataga aaacaatttg aagaatataa
    37321 aaaggtatta ggaaatgaaa taccttctaa atttgatgaa tatcaacata tgaagtataa
    37381 tgatactata aggtatgagg aagctaaaaa gctttataag gatgtaaatt ggcaagttaa
    37441 gaatcagaga aatttaacta gtggaagtgt tcattcagtg ccatttgaat caaaaccaaa
    37501 tagtgtattt gataattaca aagatggtaa attaattcaa agaagatact atggtaatac
    37561 aggaaaacct agattagatt tagacttaac tgaccataga aacccaaagc aacataaaat
    37621 tgtacctcat aaacatgatt ggttagctga tgaaaataac catgataagg taaaaagaga
    37681 gaaggatatg gagcttacaa aagctcataa aatagctaac aaagatattt tgaatggaga
    37741 ataaaatgga taataaattt aagaatttac aacatttaat tgattctatt gatttaggat
    37801 tagatataga atttgactta tataataaac catataatat atctattgga gatgatgata
    37861 caaggtttat tactctttgc cctaatggag atacaaagta ttataaaaat ggtaaggata
    37921 tggttgataa ttacaacatt gatggtaaat tactaaagga tttatggaaa gatatacaaa
    37981 tagtaaatat gtaaaagcac ttgctaaata ataaattagt aggtgctttt attttgtaaa
    38041 aaatgaaagg agaaatttaa aatggattgg ttaaaagaat tgctagaagg aataaaagta
    38101 gaggataaca aaattgatgt agcttctctt caaaaatcta tagaaaagaa aataaaggag
    38161 actacagtta ctcaagaaga ttatgtaaat cttgaaacac aacttaatac agctaatgaa
    38221 actattaaaa agtttgaagg aggtatgaca aaagaagatg tagagaatct aaaaacaact
    38281 tatgaaactg ataagaaaac tttggaagaa acctacaaaa aagaaattga agaaaaagat
    38341 tttaattact ggttaggtga tgcttttaaa tctgttaaat gtagagatga aatagcgtta
    38401 aaagctcatt tagacatgga agccctaaga aatagtaaag atagacaaaa agcttttgaa
    38461 gagcaaataa accctttgaa acaggataaa gattatttgt ttaatgcaac actagaaggt
    38521 gaagaaccta aaatagatac tataacacca gggcaagagc ctaagataaa tgattttggt
    38581 tttaatttta ctggggtaag acctcatgaa aataataata aataggagga aataaaatgg
    38641 cagcactaaa ttatgcaaaa gaatattcaa atgttttagc acaagcatat ccttatactt
    38701 taaacttcgg ggatttgtat gcaacagaaa ataatggaag atatagatgg acgggttcta
    38761 aaacaataga aataccaact atatctacaa ctggaagggt agattcaaac agagatacaa
    38821 tagcagtagc tcaaagaaac tatgataatg cttgggaacc taaggtatta actaatcaaa
    38881 ggaaatggtc aacattggtt catccagcag atataaacca aactaattat gtggcttcaa
    38941 taggtaatat aacaaaagta tataatgagg aacaaaagtt tccagagatg gatgcttact
    39001 gtatatctaa aatatatgct gattggaccg cattaggtaa cacagcagat acaactgttc
    39061 ttacaacagc aaacgtatta gaagtatttg ataagttaat ggaaaaaatg acagaagcta
    39121 gagtacctga aaatggaaga atattgtatg ttactccagt agtaaataca cttatcaaaa
    39181 atgcaaaaga gatacaaaga acagtaaaca taaaagatgg tggaacttct ttaaatagac
    39241 aaaccacaga tattgacaca gttaaaataa ttaaagtacc atctaatcta atgaaaactg
    39301 catatgattt tacaactgga tggaaagtag gagcaggagc taaacaaatc tttatgtcct
    39361 tagttcaccc aagtgcaata attacacctg tttcttatca gttctctaag ttagacgaac
    39421 caacagcagt tacagaggga aaatacttct actttgaaga aagttttgag gatgtattta
    39481 tattaaataa aaaagctgat gcaatacaat ttgttgttga agcatagaaa aaggagtgat
    39541 atatagtgcc acaagtaaaa aaactaaata gaatactaac catagaagaa tgtaaaatag
    39601 atgatttctt agagatggga tatgatttga tagatgaaac tggtaaggca gtaaagtatg
    39661 gcaagtcatt aagtgtaaaa gatttaatag ctgaaaataa tattttaagg tcaaaagttg
    39721 agtctttaga agaagaaaat aagcagctta aagagaaaaa taaacttact aaaaagtagg
    39781 tgaaaattat ggaaaataat ataattgatg aaatagaaaa aagacttgaa agttttggat
    39841 atatattaaa agatggagat aagtggttaa taggttttgt aagagaaaaa atagaaaata
    39901 ttattaaact agattgtaat ataaaaacta tgccaattga attgaaagaa attgaagttg
    39961 atatgatagt tggagagttc ttatttacca agaaaaatat gggtcaatta gatatagaaa
    40021 gcattaactt tgaagctgta gaaaagtcta tatcagaagg tgatacaaag gtagattttg
    40081 ctataggaag tggttctcaa acaccagaac aacgctttga tagcttaata gcttatctta
    40141 ctacttatgg taagaataag atattaacct ttaggtgctt aagatggtaa gtaaaactag
    40201 aaaagcaata gaaatgttat atagagataa atgtactata gttgagtatc agccaattaa
    40261 agaccctgta acaaaacgaa ctaacaataa agaagtgatt gtattagaaa atcaaccatg
    40321 taaactttca tataaaaata tagtttctgc tacagaaggg aaattagcta agctagagca
    40381 aactattaaa ctctttatat ctccagatat agaaattaaa gcaggttcaa aacttattat
    40441 aaatgataaa gagtatgtaa gaagtggaga atcagctata tatccaaatc atcaagaaat
    40501 aatacttgag ttatttaagg ataaagcata atggctagat ggggcagtgt tgattttaga
    40561 gagtttaaaa gagtttgtaa aaagatggag aaatttacaa agattgattt agataagttt
    40621 tgcaaggatg cagcaagaga attagcagca agactcttag gaaaagtaat tagaaggaca
    40681 ccagttgata caggattttt gagagagggt tggagtggag tagcttatgc taggtcgctt
    40741 cctgtttaca aacaaggtaa taattatatt atagaagttg ttaatccaac tgaatatgcc
    40801 ttaacacaat ggggcatata aaacccagca aaatcggtaa acgctaagtg taatagtgtt
    40861 acattataaa gtaggtagaa tatggacata gaataactct tgatttataa tgtataaaag
    40921 aggtgatttt atggcaaaat ttttagatat tacaggaaaa aaatttggaa ggctaagagt
    40981 cattaaattt tctaaagaga taaaaagcgg taaaagaaat aggaaatatt ggttatgtaa
    41041 gtgtgattgt ggaaatttca aagaaataag aactgactct ttaactagtg gcttagtgca
    41101 atcttgtgga tgtttaaaaa aagaacaaga taaattaaat ttaacagaca aataccaatt
    41161 taaaaagaaa tataaggttc aaaataaaag actttacagt atatggaagg gtataatatc
    41221 tagatgtaca gataaaaata ataaaagata caatagatat ggtgaaagga atataattgt
    41281 gtgtgatgaa tggttttgct atgataattt tgcaaattgg gcattgagta atggatattc
    41341 agagaaactt acaattgata gaataaataa tgaaggaaat tatgaatcaa gcaattgtag
    41401 atgggtggat ataaagacac aatgtagaaa taggtcaaca aatatattag taaaacatga
    41461 agaaaaagaa attacattga tagagctttc tgaaaaaaca ggtatttcat actcttgctt
    41521 aagaagtaga tattctaagg gattagtagg aaataagctt atagaaaaag ttaagattat
    41581 tgaagaaagc agagctaagt tatctattga ggatgtaaaa gaaattagaa aaaagtattc
    41641 tgatggatat acaataaaac aactaagtga aatatatcct gtaacatatt catctatatc
    41701 aaatatagtc catagaagaa catggaaaaa tatttaatta attatatatg ccaataccga
    41761 ggaaaaccta tagattgcgg ataggctata ggtttccgta gagcgtagag agtgaataaa
    41821 tataatctct ccaagagtgc tgggcaacta aataaagttt attttgttga tgatgtacgc
    41881 cgaacttata ggaaactata agagctagag gataaaaagc ctttaggata acaaaatgca
    41941 tatgttgaat ttggtcatag aactaaaaat ggcaagggtt gggttaaagg acaacatttc
    42001 ttaactattt cagaaatgga actacaaagt caagttgata agataataga gaaaaaacta
    42061 ttaatattgc ttaaaggagt gtttgatgct taataatatt atagatggaa tatcagtaaa
    42121 gttagataaa tcgtttggag aaaaatatac aatttatagc gaagatgtgg agcaaggtat
    42181 taatgaacct tgttttttta ttgttccttt aaatccaagc aagacaccat atccaagcgg
    42241 gagagaatta aagaaaaatt cttttgatgt acattatttc cctcgttcag aagataagaa
    42301 ttttgaaata aatgagatag ctgagatgct actggaggaa ttagagtata tagaaattga
    42361 tggagattta gtaagaggta caaatatgaa ttttgaaatt atagacaatg ttcttcactt
    42421 ctttgttgat tataactatt ttactataaa aaataatgat accaataaga tggatacagt
    42481 agagttattc ggtggtttga agagaggtga taattttgag taaagcatta agcaaagaag
    42541 ataactacaa gtttactaag gagcagatag ttaactctaa gaagtatgta aatagaaaag
    42601 atttattaaa tgcaatttta aaagaaaatg agttatattc cttctcagag gtagaggata
    42661 gaataaataa atttatgaaa ggagtgagtt agatggcttt aggtggagga acattcgtaa
    42721 cgcaaaataa aatacttcct ggtgcatata taaattttat ctcagctaag agggcaacca
    42781 gttcattatc agatagaggt attgttgcaa tgcctttaga gttagattgg ggcatagatg
    42841 aagaagcatt ccaagtaacc agtgatgatt ttgagaagta ttcagtgaag tattttggat
    42901 atgattatac tcatgagaag ctgaaaggtt tgagagattt attcaaaaat ataaggttgg
    42961 gatattttta taaattaaat aaaggcgtta aagccagttg tactatagcc acagcaaaat
    43021 atagtggtat aagaggaaat gacttaaaag taacagttac aacaaatata gatgataatg
    43081 ctaagtttga tgttgtaata cttttagata ataagaaggt agatactcaa atagcaaagg
    43141 ttattacaga cttacaagac aatgactata tcacttggaa gaaggatgca acactagaag
    43201 caagtgcagg acttgtattt actggtggaa ccaatggcga agctgtgaca ggagcagagt
    43261 accaagcttt cttggataaa atagaaagtt attcatttaa tgcactaggg tgtttggcta
    43321 caacaacaga aattaaaagt ttatttgtag aatttacaaa gagaatgaga gataaggtag
    43381 gagctaagtt tcaaacagta ctatataaga aaagtgatgc agattatgaa ggtgtagtgt
    43441 ctatagaaaa taagattaaa gataaagatt tagttgaatc tagcttgatt tattgggcta
    43501 ctggagctat agcaggatgc gatataaata aatctaatac taataaaaag tatgatggtg
    43561 agtttgatgt tgatgttaat tatacacaaa tacaacttga agaagcttta aaaactggta
    43621 aatttatatt ccacaaggtg ggagatgaag ttcatgtgtt agaggatata aatacttttg
    43681 tatcatttac agatgataaa aatgacgatt tttcaagtaa ccaaagtgtt agagtacttg
    43741 accaaattgc taatgatatt gcaactttat ttaatgaaaa gtatttaggt aaagttccga
    43801 atgataaggc aggaagaata agtttctgga atgatgttgt taaacaccat aaagaattag
    43861 agaatataag ggcaatagaa gattttaaaa ctgatgatgt tagtgtagag cttggaaatg
    43921 ataagaaaac tgtcatagta tctgatgcta ttaaggtaat aaatgctatg agtaagcttt
    43981 atatgactgt ttcagttaat tagagaggag agtgataata tggctcaaac aataaatgct
    44041 aaagatacag ttagtgcaaa gaaagctgaa tgttttataa ctatagaagg taaaagatat
    44101 aattttatgc aagctataga tttagaggct aaaatggaaa aaaataaaag tgaagttcca
    44161 attctaggaa gaacaacaaa gggaaataaa acaactggga gtacaaatac tggaagtgca
    44221 acatttcatt ataatacttc tatttttaga gaattacttt acagatataa agaaactggt
    44281 gaggatattt attttgacat acaagttaca aatgaagacc ctacatctgc tgtaggaaga
    44341 cagacagtag tacttaaaga ttgtaatatg gacagtggaa taattactaa atttgatgct
    44401 gatggtgagt atttagatga agatatggat ttcacttttg aggattggga attagttgaa
    44461 tcctttgcat tacttaatgg aatgttataa aattgaatta tacttgaaaa atattatgat
    44521 gtaagtataa attatttgga ggtatttcat ggaatttgaa agtggaatta aattaggcaa
    44581 acttacttta attaaatatt tagggagaaa taaacatagt aaaaaagtct ggctatgtca
    44641 atgtgagtgt gggaataaag ttgagagagt agaaaataat ttaaagcaat caattaaaaa
    44701 tgagaagcct ccacattgtg gttgttctcc aaactggaaa ggacaaaata agagatttaa
    44761 agatataact gggaaaactt ttgggaagct tacagtattg aaaatgtctg ggaaagataa
    44821 atatagtcac aatttatggt tatgtcaatg tgaatgtgga aatagaacaa taactagtac
    44881 aagtgcatta gaacaaggaa aagcacaaag ttgtggctgt ataagaaagg aaatattact
    44941 agagcgctct acaacgcata ataaatctaa tgatagctta tatagagttt atcaccgtat
    45001 gattaaaagg tgcacaaata agagtaataa agattataat tattatggag gtagaggcat
    45061 agaagtatgc aatgaatggc tagaggattt tataaatttt tataactggt ctatagaaaa
    45121 tggatataga aaaggtttaa caatagatag aattaatgtg aatggaaatt acgaaccatc
    45181 aaattgtaga tgggttactt gggaagttca acgaaataat aaaagaaata gtattagagt
    45241 taattataaa ggtgaaatga ttactttaaa acaatgtgca gaaaatttga atgttaagta
    45301 tctatttctt tataatcaat tagttactaa aaaaattcca ttggaagaag taataaaaaa
    45361 tataggtatg gagtaaaata cacatttata agttataaat gtgtattttt tatatgaaaa
    45421 attaaaataa aaggagatta gaataatatg agtaatttaa gtgctttttt aagtcaaaat
    45481 gcaataaagg ttgataatgt aaaatatgta gcgagtaaca gatttttaga taaagaaggg
    45541 aaaccagttg aatgggaatt aaaagtttta tcatctgaag aagacgaagc actaagaaga
    45601 aagtgtacta aaagagtaaa agtgattggt aacaatggta agcatactgg acaatataca
    45661 agtgaaattg actacaatag ttatgtagct gaattatgtg tagcatctac agtatttcca
    45721 gatttaaagg atgccgaact ccaaaatagt tatggagtaa tgggagaagc tcagttatta
    45781 aagacaatgc ttacagcagg tgagtatgtc aattatacag taaaagtgaa tgaagtcaat
    45841 ggatttgata catcttttga ggataaagta gaagaagcaa aaaactaatc agaggtggcg
    45901 attttgatgc tagcatcact cattattgta ttcaaaaatt aaagtggaag ccaagtgaat
    45961 atatgaattt agaagttaat gagagagcgt tagcagccgc ctcaatactt ataaagatag
    46021 aagatgaaga ggaagcaatg aaagaagctg aaagagagag aaagagggga cgaagaagat
    46081 agcaaaataa aaaaataaat atagaatagg taaaatatgt aataattata tgttataata
    46141 tttttagcaa gaagatgtaa tctacaattt atagagtgga gttcatactg ggataaaacc
    46201 tacttcctaa tgaaaggagg tgggaagtat gaataacttt ttacttaatg taatagctgg
    46261 cgttattgct agtttaatat tttgcttaat ttgtaaagta tttctaaaag taaaaagcca
    46321 ctcaactcgt ggcaagagta aaagtggctg ggaatttgat tttaaaatca agttccacaa
    46381 atttaaataa ttactaattg tttaaattat gaacttcact ctactgtcaa atagattgta
    46441 gttctt
//
LOCUS       DAMJWO010000020        46423 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.021, whole genome shotgun sequence.
ACCESSION   DAMJWO010000020 DAMJWO010000000
VERSION     DAMJWO010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46423
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.021"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..2504)
                     /locus_tag="PC366_001212"
     CDS             complement(<1..2504)
                     /locus_tag="PC366_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HDF2576746.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQST
                     ALSDSRGGYKFEENNKWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANQG
                     VYVEPSIFTTITTFDGQLLVKNAPEEHKVVDPEVAYVVTDMLESVITEGTGGVATLPK
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQPEENNNNNNNTGDNGGGSTPPD"
     gene            2718..3416
                     /gene="yunB"
                     /locus_tag="PC366_001213"
     CDS             2718..3416
                     /gene="yunB"
                     /locus_tag="PC366_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HDF2576747.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
     gene            complement(3628..4635)
                     /locus_tag="PC366_001214"
     CDS             complement(3628..4635)
                     /locus_tag="PC366_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HDF2576748.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLLYFFSNNLIYA
                     QNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNSEVDGYSDF
                     ANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTSEF
                     GAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENTDF
                     GIRGQINNFDISNLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIENQKHPE
                     SKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIKWM
                     L"
     gene            4863..5747
                     /locus_tag="PC366_001215"
     CDS             4863..5747
                     /locus_tag="PC366_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2576749.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ADKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDKKNKIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDAYFK"
     gene            5949..7499
                     /locus_tag="PC366_001216"
     CDS             5949..7499
                     /locus_tag="PC366_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2576750.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKEKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETENLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            7528..8163
                     /locus_tag="PC366_001217"
     CDS             7528..8163
                     /locus_tag="PC366_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HDF2576751.1"
                     /translation="MKKFLNVLFSVCISIVIIVGVINFTVGFKQLYYFDIDYLNISEL
                     SGLSEDDIKLNYDYLIDYNLNKNVSEFKLPTLKSSPQGKIHFEEVRNIFQNINKLAKL
                     LLVVFLVGIILSVKNKNIKILKTTSITLIIMPLLLTVPILLNFEKSFIIFHKLLFRND
                     YWIFNPNLDPVINILPEEFFFHSGMMILILILLASILLFVMYRLYKSFKIK"
     gene            complement(8274..8534)
                     /locus_tag="PC366_001218"
     CDS             complement(8274..8534)
                     /locus_tag="PC366_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HDF2576752.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFKYTDKGIKDCSSCMLPHKKDNYNYIMGKFQDLVKITSKK"
     gene            8751..10034
                     /gene="hflX"
                     /locus_tag="PC366_001219"
     CDS             8751..10034
                     /gene="hflX"
                     /locus_tag="PC366_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDF2576753.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTSESMEELKELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYADLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGENGITLDVNFDEEDFNIYREYILEK"
     gene            10042..10719
                     /locus_tag="PC366_001220"
     CDS             10042..10719
                     /locus_tag="PC366_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HDF2576754.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEAGEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDEAIKSLE
                     NAKNLKK"
     gene            10805..11248
                     /locus_tag="PC366_001221"
     CDS             10805..11248
                     /locus_tag="PC366_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2576755.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTNCVLAPEFQE
                     GGFYKVKDALDMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            11554..12198
                     /locus_tag="PC366_001222"
     CDS             11554..12198
                     /locus_tag="PC366_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HDF2576756.1"
                     /translation="MSNYRTLHEFGTDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVVVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITNGTGKIILGEEFYLSEQNGEILI"
     gene            complement(12284..12661)
                     /locus_tag="PC366_001223"
     CDS             complement(12284..12661)
                     /locus_tag="PC366_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDF2576757.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(12661..13047)
                     /locus_tag="PC366_001224"
     CDS             complement(12661..13047)
                     /locus_tag="PC366_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDF2576758.1"
                     /translation="MKKTDDLKKKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            13226..13981
                     /gene="nadE"
                     /locus_tag="PC366_001225"
     CDS             13226..13981
                     /gene="nadE"
                     /locus_tag="PC366_001225"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HDF2576759.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYRAEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            14064..14783
                     /locus_tag="PC366_001226"
     CDS             14064..14783
                     /locus_tag="PC366_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2576760.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(14951..15955)
                     /locus_tag="PC366_001227"
     CDS             complement(14951..15955)
                     /locus_tag="PC366_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDF2576761.1"
                     /translation="MATIKDIAKDCGLSSATVSYVLSGKGNERRIPLHTQELILNSAD
                     KLGYKRSTPIKHNNIKIAFYWQDEGFELASTNILQAINHIISLEHLNINIIIRPYKVG
                     HLCDDEYFFANNYYDGIVLTGINADDIEYLVKNKPKIPVVVVNREIPGFSSVSIDNEE
                     TGRIAALHAIQNGKNDIAVVFNPTSFTCMTLRGKSFLKTCKEHGIHLSDSIYYCSNKI
                     DSGYDIAQKMLAKNSLKKVIFCNHDVVALGMMNAFHESGIVIGEDIQIFAASNGPSRL
                     MARSIPPLTVIDLKMEETAERSLRMIIDTVTGRINGIQQQVIYPSIIYRQSSPAQNLL
                     "
     gene            16221..17117
                     /locus_tag="PC366_001228"
     CDS             16221..17117
                     /locus_tag="PC366_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HDF2576762.1"
                     /translation="MSKVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEI
                     SSFVSPKAIPQMKDAKEVATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISL
                     SETHNKKNINRTHEESIDELKKIMNTYPDMNICIGMATVFGCPFEGLPKIEDAIRFAK
                     RLWENGIREINLADTIGIADPKQVRETISALVEALPECRWQVHIHDTRNMGMVNTLVA
                     IESGITTVQSTLGGLGGCPFAPGASGNTATEDLVYMLERMGYDTGVDFVKLLELSKYQ
                     KSFVNGVYSGHHVNIKSDSCNC"
     gene            17255..18517
                     /locus_tag="PC366_001229"
     CDS             17255..18517
                     /locus_tag="PC366_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576763.1"
                     /translation="MDIIALLLFLGVIIIAFVRKNNAGILALAIGVIAVRIFGMDDKE
                     LYGAISNSMFTTLVGITLLFAIVNSTGALKLVAEKIVAASGKRVWLIPIAVFIAGFVV
                     AGVGPGAIPALAIIPAMAVPVAITVGYNPVMLALIGECGLMAGRMTPITPEGQIITTV
                     AEGVGIENVMPTILACQTLSTIVFSIVLFIIFKGYKLKKPINVIDSKQIEKFNIKQII
                     SLISIVVMIAFIIIFDMNVGLAAFAVSAVLIFFNIADEGECIKSIPWSTIVMVLGVGA
                     MMTIVDAAGGIDLMSNALSSLMNSKTATPIMSISAGLMSMVSSALAVVYPTMMPMCVD
                     IAKAVGGVDPLALIAAVGVGGSLAGVSPLSTGGALILAAMGSSKKDFNKEEQNKVFVQ
                     LFIMSAVGLLVIAVVSILSFNAITHLMN"
     gene            18593..19786
                     /locus_tag="PC366_001230"
     CDS             18593..19786
                     /locus_tag="PC366_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HDF2576764.1"
                     /translation="MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGD
                     DTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVM
                     EKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
                     TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDS
                     GQPELMGNRYASAYPYDSFKASDGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTN
                     LKRCEHYKALKPEIEKWSVKHTIKEAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREM
                     IVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLK
                     ENGVI"
     gene            20415..21209
                     /locus_tag="PC366_001231"
     CDS             20415..21209
                     /locus_tag="PC366_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HDF2576765.1"
                     /translation="MESVMENLNNLKVEVKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGIFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDIAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            21303..22643
                     /locus_tag="PC366_001232"
     CDS             21303..22643
                     /locus_tag="PC366_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF2576766.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNTKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            22780..24012
                     /locus_tag="PC366_001233"
     CDS             22780..24012
                     /locus_tag="PC366_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HDF2576767.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKNGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     ALIESGIVTMNKEACEIC"
     gene            24052..25194
                     /locus_tag="PC366_001234"
     CDS             24052..25194
                     /locus_tag="PC366_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HDF2576768.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGTDIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGIGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASSTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            25205..25999
                     /locus_tag="PC366_001235"
     CDS             25205..25999
                     /locus_tag="PC366_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF2576769.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFAPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            26010..27032
                     /locus_tag="PC366_001236"
     CDS             26010..27032
                     /locus_tag="PC366_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF2576770.1"
                     /translation="MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLA
                     DQLGKELEVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERK
                     KPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
                     IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEVLPQEKKSV
                     NLTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGT
                     TVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEM
                     IESLNR"
     gene            27131..28507
                     /locus_tag="PC366_001237"
     CDS             27131..28507
                     /locus_tag="PC366_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HDF2576771.1"
                     /translation="MKEQWYKDIFARILSMTDDGFIVVNTSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKDKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(28839..29183)
                     /locus_tag="PC366_001238"
     CDS             complement(28839..29183)
                     /locus_tag="PC366_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576772.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
     gene            29671..30681
                     /locus_tag="PC366_001239"
     CDS             29671..30681
                     /locus_tag="PC366_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HDF2576773.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEESTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            30817..31305
                     /locus_tag="PC366_001240"
     CDS             30817..31305
                     /locus_tag="PC366_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2576774.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEDGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
     gene            31481..33409
                     /locus_tag="PC366_001241"
     CDS             31481..33409
                     /locus_tag="PC366_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2576775.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFILSNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFENLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
     gene            33584..33994
                     /locus_tag="PC366_001242"
     CDS             33584..33994
                     /locus_tag="PC366_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDF2576776.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            34016..34318
                     /locus_tag="PC366_001243"
     CDS             34016..34318
                     /locus_tag="PC366_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HDF2576777.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(34534..35226)
                     /locus_tag="PC366_001244"
     CDS             complement(34534..35226)
                     /locus_tag="PC366_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDF2576778.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMMAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(35252..36439)
                     /locus_tag="PC366_001245"
     CDS             complement(35252..36439)
                     /locus_tag="PC366_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2576779.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRIPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSISYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            36775..38652
                     /locus_tag="PC366_001246"
     CDS             36775..38652
                     /locus_tag="PC366_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2576780.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKTVYDEVIKIVPQSNDVGKKNESQEKQSIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSFIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            38964..40370
                     /locus_tag="PC366_001247"
     CDS             38964..40370
                     /locus_tag="PC366_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF2576781.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLDFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNTVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            40398..41246
                     /locus_tag="PC366_001248"
     CDS             40398..41246
                     /locus_tag="PC366_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2576782.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            41907..42599
                     /locus_tag="PC366_001249"
     CDS             41907..42599
                     /locus_tag="PC366_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2576783.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            42596..43531
                     /locus_tag="PC366_001250"
     CDS             42596..43531
                     /locus_tag="PC366_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2576784.1"
                     /translation="MKMDEQTIILFLFLLSIGLLFLSIFAFSKLGHIHKRLKDIEEIL
                     ADVQIGNENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIGQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVDDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQISVESEIGKYTVFTVSLPLI"
     gene            43679..44602
                     /locus_tag="PC366_001251"
     CDS             43679..44602
                     /locus_tag="PC366_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2576785.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRKFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAHAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            44586..45356
                     /locus_tag="PC366_001252"
     CDS             44586..45356
                     /locus_tag="PC366_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2576786.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVPKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVTVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPLLSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            45366..46148
                     /locus_tag="PC366_001253"
     CDS             45366..46148
                     /locus_tag="PC366_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2576787.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGIAVLLSLFSFLCTFILGLLFCNINISVTLIVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
BASE COUNT        17136 a         5655 c         8434 g        15198 t
ORIGIN      
        1 ttatcaggag gagtagaacc gccaccatta tcacctgtgt tattattgtt attattattt
       61 tcttctggtt ggttattgtc tggttttttt gtatcttcag atgatggttg agaacttact
      121 ttagtaggag cagtaccttc aataaatgct gctttagagc cagaagattg ctttcctcca
      181 tcctctaaat taatttttgt aaaatataca tttttaggaa cttcaaattc agtaaccgtt
      241 aaattagcat gtattttttc cataattttt tcccatagtt ttgcagtact agtacttcca
      301 tgtggtactt ctctacgttt tatagtgtta ccagaatcat cttttctacc agcatcatct
      361 ccaatataag ttgcaccaac ataataagga gtgtaaccga caaaccaagc atcatatgca
      421 ctatttgtag tacctgtttt acctgctaca ggcattccct ttggaagtgt agcaacacca
      481 ccagtacctt cagtaattac gctttctaac atatctgtaa caacataagc tacttcaggg
      541 tctacaactt tatgttcttc aggagcattt ttaactaata attgaccatc aaaggtagtt
      601 atagtagtaa aaatagaagg ttctacataa acaccttgat ttgccaatgt accataagca
      661 gcagccattt gaagtggagt aataccattc gccataccac ctagtgtcaa tgatgggaat
      721 tttctatcac ttgcttcaga tgaacctgag tgattattct ttaaagttgt tataccaaag
      781 ttctttaagt aatccatcat tatatctaca cattcatcat aagagtctcc aagcatttca
      841 gcagttttga cagctatcgt gtttgaagat ttagcaagtg ctttacgtaa actcatagaa
      901 ccatgaccag cagtagtagt tcttggattc catttattat tttcttcaaa cttatatcct
      961 cctcgagaat cacttagagc agttgattgt gttattttta gggtatcaat agcaggtgta
     1021 tatattgcta aaggttttat agaagaacct ggctgatgag ggttagtagc acgattcaaa
     1081 gtttttctac cacttatatt tcttcctcca gctagtgctc ttatttcacc atttttataa
     1141 tctaagatta ccattgcagc ttgtggttgg ctaactccat cagggccgac catatgtcct
     1201 gggaaattgc tatttctatc aaattcttct tctaaagcat cttgcatttt agggtctata
     1261 gttgtgttta caattagacc accattgtag aataagtttt gagcttcatc atttgtatgt
     1321 ccttgttcca ttaaagcatt tataacttca ctttcgataa ggtcttctac agatgaagaa
     1381 actttatctg atgattgagg caattttatt tctattttag ctttgattgc ttcatcatat
     1441 tcactttgtt ttatatattt caattctaac attttcttta aaacaatttc ttgtcttttt
     1501 ttagcttcag ggttacttac agcctttcta acaactaatg tacctgcttt taattgtcta
     1561 taagtatcat tagatataag ctcccaagat tttatttttt caatcatatc aaagtccact
     1621 tgagtagggt catctaaatc atcatcagtt gtgttaacaa aaaataataa tttattttct
     1681 aaatcctcct tagtttcatt tccctctaac ttagaagttt tataggctga aaatcttgat
     1741 ggatttttag ttgaaccagc aagaagtgct gactctgcta gagtgaggtc agctgcagac
     1801 ttatcaaaat aaccacgtgc accagcctca gcacctgcta gacctctacc aacgaagaag
     1861 ttatttaaat aagtttctag tattttatct ttacttactg ttttactcat ctcatgtgca
     1921 tagtaaatat cctttatttt acgaggtata gtttgctgtt cagttgttaa cagcattttg
     1981 gatacctgca taggaatagt actaccacct tgcttagtac ctgtaagggt ctttaatact
     2041 gacctaaata aacctttaat atcgacaccc ttatgctcat aaaaacgctc atcttctatt
     2101 gcaattacag catgttgaag ataaggggaa atcttatcta atggaacggg tgtcttttta
     2161 tttacacttg gagctgtaga caatgttttt ccattagcgt atttaatagt agttgtttgg
     2221 ttcgtctgtt tatctaaaac agcttctgta actggagtta catctcttag tgacgcaaat
     2281 actagaccag cagtacctgc tgtaccaaca actagtaaaa ctaaaaatac tatcccaaat
     2341 actcttagtt ttttaaattt atcgcttttt ttagattttt tcttgttttt tgttgaacga
     2401 gtcttgttag ctgaagttct attaattggt ttatttgtat taccagatga gctaactttt
     2461 tttctcctga ttttatttcc atttttatca ttatcgttat tcataagatt ttaacctcct
     2521 tacttaatgc aatattataa cacaaatagg agtagttttg taattaatag aaaaaatgaa
     2581 tttgctataa tattctgtac attgtatatg tataaacgta atatattaaa aagtctatat
     2641 ttttatttta tttatttttg acaaatatta taaaaattat gccaaagcta catataaata
     2701 aataggaggg gataattttg aatagaatag tagatagaaa aacaaaaaat gaatttagaa
     2761 aaatcatagc tattttttta gtaattcttt tcttgtctgt atttataggc agttttatat
     2821 atatagataa aactttaaga ccgacaataa cagttttagc agagactaaa gctcttgaac
     2881 tagcaaatag gtcgataaat aaagctgttg ctgagatggt agaaggaaaa ataaattatg
     2941 aagatttaat ggatatacaa cttgataata atggtaaaat aactatgata caagcaaaca
     3001 ctataatgat gaatgaaatt gcatctgcaa tagctttaga aatacaagat gaattaaaaa
     3061 aggataagac agcaagttct tacataccta taggaacagc attaggaagt cctatattag
     3121 ctaaatacgg tcctaaactt gaagtgtcta ttgaacctat aggaacagta tcagtaaact
     3181 ttaaaacgga atttgagtct tcaggtataa atcaaactag acatagaata tatttagaag
     3241 ctcaaacaca agttaaagta gtaataccac ttataacttc aacaaaacaa attaaagctc
     3301 aaatacctat ttgtgaaact ataatagtag gtgatgttcc agaaagttat gtaaatattc
     3361 cagaaaaaaa tctaggaaat gttttaccta acactggaaa gaataccaac aagtaatata
     3421 aagttgtata tttttaaata aattcaaaat aatagtttat aaataaaatt tttggaaata
     3481 atattaatat aattttaata aaaatttata ttttatacta tgtaaaatat ctaatatatt
     3541 tggtctgtag gttaaataaa agtaccttta gaccaaatat attattaata acttaataac
     3601 atcttaaaac ttatttattt atattattta caacatccat ttaataaata caccataacc
     3661 tacagctggg tcattttcaa ttgcatgtga cactgctccg attattttat tatcttgaac
     3721 tattggagta ccactcatac cttgtacaat accaccagtt tgagctaaaa gctttttatc
     3781 tgtaatttta attttaaaac ttttactttc tggatgtttt tggttttcta tatctataat
     3841 ttcaatatta tattttttac acttattaaa gttatcttgt aaaattattt gagcttttcc
     3901 taatttaact tcatctaaag atgctacttt atattttttt aaattggaaa tatcaaagtt
     3961 attaatttga cctcttattc caaaatcagt attttctgta aagctaccaa taatattttc
     4021 tcgttttgca tttatacatc caacactacc tttataagat ttttctatat taaggtgctt
     4081 agttgtagaa attgaacctg ttttaatagg tatttttctt gcattaccaa cacttattgg
     4141 atgacctaca gctccaaact ctgatgtatc tggattgata tacgttaaag tagcaaatcc
     4201 agaaagtaaa ttgttaaaac taattttttc taatatgtgt ttggtagttt tcattgttat
     4261 aagttgtcca cctctattta ataaaataga tacttgtttt tcttctggta aagcatttaa
     4321 ggtattggca aagtcactat atccatcaac ttcagaatta tttaccttta ctatagcatc
     4381 acccaatcta aatggagatg cttctccagg atttctaact atgatatttt ttaattctgc
     4441 gtcaatttga agtacgtttc caattggtat taaatattca ggttcatttt tttgtaaatt
     4501 ttgtgcataa attaaattat ttgagaaaaa atataataaa aataaaaatg ttaaaacaat
     4561 tgtaaatttt gacttagcta agttggtttt tttacttaaa gtattatttt taaaatgaaa
     4621 atttttaagt tgcataaaac acctctttct tattaaatta ttttaataat agaattgaag
     4681 ttttcttgct gcttctatat tatgttgtgc aagaattatg ttttgatgct tggaaaactg
     4741 actcaataac accttagttt tcataaaaat aaataaaata aatagtgtat atgataaaat
     4801 aaatacatat tcatataaat aaaaataaac aataactgtc tagcataaga aaggagcaaa
     4861 aaatgaaaaa atatagattg ttagttactt gtataattgc catgggaatc ataattatag
     4921 gaacatcaaa tccagttagc aatttttaca agactacaaa tttgattagt tcaggaaata
     4981 tcacaaatga aaaagcagat aaagatgaaa attcaaacaa aaataataaa gataaaaatg
     5041 aagacaaatc taattctaaa agtaataaag ataagtcatc agaggacaaa tcgtcagata
     5101 aaaaaaataa aattcaaaaa aataaaaaac ttttaatttg tatagaccca gggcatcaag
     5161 gaaaaggaga tagcaattta gaaccagtag ctccaggttc ttcctctaaa aaagcgagag
     5221 tatcttcagg aacagagggt attgctacaa aaaaaccaga atatgttcta aacttagaag
     5281 catctcttgt tttaaagagt atattagaat ctaaaggtta taatgtaata atgactagag
     5341 agacacatga tgtaaatata agtaattcag agagagcaat acttgctaat gataaaaaag
     5401 cagatatggt tgtaagaata catgcagata gtttaaataa ttcttcaaaa actggagcat
     5461 ctatattgat tcctgaaaaa gatggaaaat atacagctcc tatatatgaa gagagtaata
     5521 aatgtgctga atttatcaaa cagaatatgg aacaatcagg tatacaaatc aatggaatcg
     5581 ttcaaagagg tgatttgact ggatttaact ggtcaaaagt accagccgta ttagtagaaa
     5641 tgggatttat gagtaactat aatgaagacc aaatgatgtc aaatccagac taccaaagaa
     5701 aaatgatgca gtgtatagct gatggattgg atgcgtattt taaataagat atgaatagag
     5761 aaaaagttag gttggtatta ttttcctaat ttttatctct attttttatt gtacataatg
     5821 caaagaagaa gtttatttta ggttaaattg tcgtaaatat aactaaaaat attgggaata
     5881 cttgatttaa gtttaaaaag aatatattat agtatagaat gtgtaaaatt tttttgagag
     5941 gtgttgaaat gctagtagta gaaaatgtga gtcatggatt tggtgcgaga acaatattag
     6001 aaaatgtatc ctttagactt agaaaaggtg aacatattgc actagttggt gctaatggag
     6061 aaggaaaatc gagtttttta aatataataa caaagaagct tatgccagat gctggaaata
     6121 taaaatggtc ttcaagagct acagtaggtt acttagacca acatacggta ttaagcaagg
     6181 aaaaaactat aagagaagtg cttagagagg cttttaagca tatgtttgac ttagagcaag
     6241 aaatgattgc tatgtatgac aaaatgggag aagctagtga tgatgaaatg agtaagcttc
     6301 ttgaagaaac agcagagata caaactatac ttgaaaatag tggtttttat atgatagatg
     6361 caaagataca agaagttgca aatggtcttg gtcttggaga aattggtctt gataaagatg
     6421 taactgactt aagtggaggg caaagaacaa aagtacttct tactaaactt ctacttgaaa
     6481 atccaactat tcttatattg gatgagccta caaactattt agacgaagag catataacat
     6541 ggcttactaa gtaccttcaa gagtatgaga atagttttgt cttagtttct catgatattg
     6601 aatttataaa taatacatgt aatgtaatat atcatatgga aaatggagag ttaaatagat
     6661 ataaaggaaa ttatgatgaa tttgtaagac ttaatgatat aaagaaacgt caagaagaac
     6721 aagcttatga taaacaagtt gaagaaagaa aaagactaga ggattttgta gctagaaata
     6781 aagctagagt agcaactaga ggaatggcta acagtagaca aaagcaactt gataagatgg
     6841 aaatattaga aagaccaaaa gaaaaaataa aacctacttt tgcttttaaa gatgctagag
     6901 cagctagtaa aataattttt gaaacagaga atttagtttt agggtatgat gaagcattga
     6961 caaaaccact taatttccat ttagaaagag gaaaaaagat tgccttaaaa ggaatgaatg
     7021 gtattgggaa atctactcta ttaaaaactt tacttggaat aataaaacca tttgaaggaa
     7081 atgttaaatt aggtgactat ttggaagttg gatattttga acaagagagt tcaagggaaa
     7141 atagtaatac acctatggat gaagtttgga gtgaatttcc agggcttaca aactttgaag
     7201 ttagacaggc tcttgcaaaa tgtggactta caaatgaaca tataacgagt caaatgagag
     7261 tattaagtgg tggagaagct gctaaggtta gactttgcaa agtaatgtta aaaaatataa
     7321 atttcttagt attagatgag cctacaaatc atttagatgt tgaggcaaaa gatgaattga
     7381 agaaggctat caaagagttt aagggaacag ttcttttagt atgccatgag ccagaatttt
     7441 attcagaaat tgttgatgat gtatggaata tagaagattt taccactaaa atcgtgtagt
     7501 gatttaactt attgctgggg ggatttcatg aaaaagtttc taaatgtact tttttcagtt
     7561 tgtattagta ttgttataat agtaggtgtt attaatttta ctgttggatt taaacaactt
     7621 tattattttg acattgatta cttaaatata tcagagttat ctggtttatc tgaagatgat
     7681 ataaaattga actacgatta tctaattgat tataacttaa ataagaatgt gtctgagttc
     7741 aagttaccaa cattaaaatc ttctccacaa gggaagatac attttgaaga agtcaggaat
     7801 atatttcaaa atataaataa attagctaaa ttattattgg tagttttttt agtaggaatt
     7861 atattgagtg taaaaaataa aaatataaaa atcttgaaaa ctacatcaat aacacttata
     7921 attatgccat tattattaac agttccaatt ttattaaatt ttgaaaaatc atttattatt
     7981 tttcataaat tattatttag aaatgattat tggatattta atccaaattt agacccagtt
     8041 ataaatatat tgccagagga attttttttt cactcaggaa tgatgatttt aatattaatt
     8101 ttgttagcaa gtatcttact atttgtaatg tatagattat ataaatcttt caaaataaaa
     8161 taagatagca aaaacgaatt atattaaagg ttatacaata aaaatagcta tgtaataata
     8221 tttaaactaa gagtagtcga taaatattta tgcatagcta tttctaatag aaattacttt
     8281 ttactagtga ttttaactaa atcttgaaat ttgcccataa tgtaattgta attatctttt
     8341 ttgtgaggta acatgcaact actgcaatct ttgatacctt tatctgtata cttaaagttt
     8401 ccaccacagt tttctcctaa agcatacaaa ggacaatagc aaaatagaca gttaaactct
     8461 tctggtttat tagttttatg acaagggaaa aattcgcaat ctttgtgatt aaaaaactta
     8521 taattttcgc ccatattttc ctcctaatta aataaaattt aaatttttta tactatataa
     8581 gattttggtg ataatataat tatactaaat aattttatga atagtcgata atatagtatt
     8641 attaatcata gtattaatgg tataattagt caacagaaaa ataatgtaaa aattatgtaa
     8701 gtgtattttg taattagaat atgttttata acaaaaaatg aggtgattaa gtgaaagaaa
     8761 ttcaagaaaa agcacttctt gtaggtctga atttgactac aatagtgaaa aaaaatgatg
     8821 atatagacac tagtgaatct atggaagaat taaaagagct aacaaaagct gctggggcag
     8881 aagttgtagg tagcttaatt caaaataaac attctgtaga tgcagcttat tatataggaa
     8941 aaggtaaagt agaagaaata agagcctata gtgactcttt agatgctact ttagtaattt
     9001 ttaatgatga attatctggt gctcaaatca gaaatataga gaatgttgtt ggaagaaaag
     9061 taatagatag aactacttta attttagata tatttgctca aagagcactt agtaaagaag
     9121 gtaaattaca agttgaatta gcacaattaa aatatagatt gccacgactt tatggaatgg
     9181 gtggtgagat gagtagaaca ggtgcaggga ttggtactag aggtcctgga gaacaaaaac
     9241 tagaaataga taagagacat atacttaata aagcagcaga cataaggcgt gaacttaaag
     9301 aagtaaaaaa gaatagggag acacagagag ttaagcgttt aaagtcaaat ataccgattg
     9361 tagcacttgt tgggtataca aatgcaggaa aatctactct tttgaacgaa ttaataaaga
     9421 cacacaagga ttatgaacaa gaaaaagaag tttttgtaaa agatatgctt tttgcaactt
     9481 tggatgtaac tctaagaaag gctcttttgc cgaataaaaa agaattttta gtagtagata
     9541 ctgttggatt tgtaagtaaa cttccccatg atttagtaga ggcgtttaaa gcaacattgg
     9601 aagaagtaca gtatgcagat ttaattttac atgtaattga tgcgacaaat actagttatg
     9661 aattgcaaaa aagtacgact gaaggtgtat taaaagaact tggtgtaaat gataaaaaac
     9721 atatacttgt atataataaa gtggataagc tagaattgga tatatatcct aaaagtcaag
     9781 aagatattgt gtatatttct gcaaaacaag gcataaatat ggataagcta ttaaatatga
     9841 tagaaattgc tttaatggaa aatacttatt cagtaagctt gatgttacct tatgagagag
     9901 gtgatatatt tagtagaata aaagataaat ataatgtgga gaattttgag tatggggaaa
     9961 atggcataac gctagatgta aacttcgatg aagaagattt taatatctat agagagtaca
    10021 tactagaaaa ataggttgaa tatggatata aattgggaaa atatagataa tcttgaagat
    10081 tattttataa cctatcttct ttataaagaa tctaaaacag tatctcaaat tagtaaaatt
    10141 agaaatattt caagtactga agcaggtgag caacttatac aagcaaaatt aaaaataaag
    10201 gaaatgcaaa aagatgattt tgaggcatct aaggatattt tagataaatt tttagaacta
    10261 gataaaatta agagacttga ttttatggat agcttagatg acgaaaaaat ggtatacttt
    10321 aagagaaagg ttttcaaaag aatccttgtg gaaaaaaatg ctgaagattt aattgtttta
    10381 atttgggcga caggtgagct aaaagatgat agattcttaa agttgcttca tcagctcaca
    10441 aaccacagac actcagatat tagaagaata acttattcag caatcagaaa gattgaatca
    10501 ccaagtagta gagaagtact gcaaaaaggt ctctacgata aaaatgcaca aactagacag
    10561 tattgtgcaa aggctctttc aaaactaggg gatgaaaaca gtttaaagat tttacagcag
    10621 ttgaaagaca agaataagaa ttttgaaaaa gaatatgtgc ttagagctta tgacgaagcc
    10681 attaagtcat tggaaaatgc aaaaaatttg aaaaagtaat tttttattaa agcaatttgt
    10741 ttacttaatg atgtatttct agagtttaac aaggtaataa ataaattaat gggaggggtt
    10801 tcaaatgata gtaagacgtt gtgcaggtgg agtagtgttt tatgctaata aagtacttat
    10861 tgtaaaaaat gataggggag aatggacact tccaaaagga aagatacttg gaggaggact
    10921 tccatatgag agtgctgttc aaagagttaa agtagaaact ggcatagatg ctaaaatgat
    10981 agatgtggct ggcgatacta tgtatgaatt tttctcaaga agtagacaac aagaagtttg
    11041 taatgcaata atgtggtatg ttatggaagc ttgtaacact aattgtgtac ttgctcctga
    11101 atttcaagaa ggtggatttt ataaagtaaa ggatgcttta gatatgttat cacatcataa
    11161 agagcaagct ttagtagaag tatcttataa aaagtttaag gaattaaaga aattagtttc
    11221 agagggcgat gatgttccag caaattaatt gtgaatttag aggattctga ggaagggata
    11281 gccccttcct tttttaattg aagcagtttt aagcgtaaat tatatagtct ctttaaatta
    11341 tgatttatca atttagagct ttagtagttt atatttaaaa tcagtaagat atatttaaaa
    11401 taaaaattaa aaagtataca attttattat ataattgtct tatgatattg attaaagaag
    11461 tattaaaagt ccatttattt ttaaatagaa taattttata gatatataat ttgatgtgta
    11521 tattagaaaa tgattaaaat aggaggaaat acaatgagca attacaggac attacatgaa
    11581 tttggaacag atgaaataac tattgaaaag tctgttttta ttggatatgc taagcctata
    11641 aagagtgaag aagaagcatt agagtttata aatgaaataa agaaaaagca taaagatgca
    11701 actcacaatg tgtgggctta tactgtaggt aaaaatatga atatacaaag atatagtgat
    11761 gatggagaac cacaaggaac agctggaata cctacattag aggttataaa aaaagaagat
    11821 ttgagagatg tagtggttgt tgttactagg tattttggag gaacaaaatt aggtgcaggc
    11881 ggtctagtta gagcttatac aaaaggtgct aaattgggac ttgaagcagg taagataatt
    11941 tataaggtaa tgtatcaaga agttaaggtt aagatagact atactcaact tggaaaagtg
    12001 caaaatgagt taatgaattt ggggtatttt ataaaagata ctgtatatga ggataatgtt
    12061 gagatagtag tgtattcaag attagaagat gtagagaaat tatcagaaaa aatgattgat
    12121 ataacaaatg gaacaggaaa aataatttta ggagaggaat tttatttgtc tgaacaaaat
    12181 ggagaaattt taatataatc taaaaggtta ttagaatagt taatacctca aatagccaat
    12241 tagtattttt aagtgaaaag ccattaaatt gatttaatct aaatcaattt aatggctttt
    12301 tatcggattt tgcacagaat ccttttttta cttcaaataa accgactaaa agtaaaaata
    12361 tcccaaatat tttttttaat atatctgaag acagataatt agctaatagt gaaccaaata
    12421 cagctcctaa aaccccaaac acagctatag gtataaccaa tttaaaaatt acatttttat
    12481 tttttatatg tatagcaagt gctataagtg tcatagggat agatgaaagt aaatttacgc
    12541 tttgtgctat tttagtgtct atgccagcaa gtaaaacgag tgcaggtata aggattgttc
    12601 ctccacccat tcccattcct ccaataattc ctgcaaaaaa tccaattaga gcaaataaca
    12661 ttaaaacacc atccttaatg ctgcaattat cataattatt ccaaaagaaa ttctaagaaa
    12721 ctttccagta accttattta gtaatttagc tcctataata ccaccaagaa tacttccaac
    12781 tgcaacttta attgttaagt taacatcata agtaccttta gatacatata aaacagaact
    12841 tgctgtcgtt aagaatatta ttatagaaag agcagttgca tgagatttat gttcttctac
    12901 cttaacgatg tcatttaata ttggaactaa aagagtacct cctccagaac caaaaactcc
    12961 atttataaat cctgtaaaaa ctccaattat cgtatttttt aagttaaaat caaagtattt
    13021 tttctttaaa tcatcagttt ttttcataaa aatcaccttc tgaaatagtt ttaccaaaat
    13081 aggcaaatta tatttatata aaataagatt aaatataatc tttcatgttt gtttaatttt
    13141 gcataaaaaa aaacatatta aaacaacata ttaatatatg gtataatata ttaaaacaaa
    13201 gtagcaaatt tgagaggaga taacaatgtc aaatataaaa atacaaatag acaaaactgt
    13261 agaatggctt ataaataagg ttaatgaggc aaatgcaaaa ggattaattg ttggtgtatc
    13321 tggaggaatt gattcggcag tagttgctaa tttaattaaa aaggcatttc cagaaaactc
    13381 tatgggagtt ataatgagca taaaaagtaa tcctcaagat agagaagatg cacttaaggt
    13441 tatagaggga tgtgatatag aataccttga tttagacctt atagaaccac aaagtgctat
    13501 attagacatg gtagtaggaa atttaaaaga taaacattta tatagagcag aatatttaaa
    13561 gatgacagat gcgaacttaa gagcaagagt aagaatgagt acaatttata caattgctaa
    13621 caatctagga tatttagttg ttggtacaga caatgctgca gaaatacaca caggatattt
    13681 tactaaattt ggtgatggtg gagttgatat tttacctatt gcaaatttaa ctaaaggaga
    13741 agtatatgaa tgggcaaaag agcttggtgt tcatgaagat ttaataaaca aagctccttc
    13801 agcaggtctt tgggaaggtc aaacagatga agatgaaatg ggaactactt acaatatgat
    13861 agatgctgtg ttagaaggta gattggatga agttcctaaa agagaccaag agataataga
    13921 aagacttcat agattaagtg aacacaagag aaaaacgcct gcacaacctc ctaagttcta
    13981 atttactatt tataagattt gtgataaaat ttacaagtga tgaaaattag aataattaat
    14041 tgtacgtatt aaggagtgga aatatgggac gtataggtaa tataattaat agaaaaggta
    14101 aacaagatgc tcaaagagca aagatattta ctaaacatgc tagagcaata gcagttgcag
    14161 ctaaagaagg tggagcagac ccagagtaca atgcagcgtt aaaaacagct atagaaaaag
    14221 ctaaggcaga taatatgcca aatgataata tagatagagc tatcgctaaa ggtgctggag
    14281 caggcgctgg agaagactat gaaactatag tttatgaagg atatggacct ggtggagttg
    14341 ctgttatagt agaaacttta actgacaaca aaaacagaac tgctggtaac gtaagatact
    14401 attttgacaa aaacggagga aacttaggaa ctagtggatg tgtgtctttt atgtttgata
    14461 aaaaaggaca aatattagtt ggtttaggag atggagtttc agaagaagaa ttgatggatg
    14521 ttgcattaga agcaggagct gaagatttca taacagaaga agatggttat gaaataataa
    14581 ctacaccaga agatttttct agtgttcgtg atgagttaaa agctaaagga tatgagttta
    14641 tatctgctga tgtgaagatg atacctcaaa ctacgactgt attgactgaa gaatctcatt
    14701 taaaaatgat gaataaatta gttgatatgc ttgaagaaga tgatgatgtt caagatatat
    14761 atcataactg ggaagtagaa taaatagtat aagcatattg aaatttataa gcattgaatc
    14821 aattttaaca tgtgataaat tttatagaat aagaaattac taaaatagac atacgcacct
    14881 ctaacctata tttgcataat aatatgtaag tataggtaag gggtgttttt atatttatag
    14941 gttaagaaat ttaaagtaaa ttttgagctg gacttgattg tctataaata attgatgggt
    15001 atataacttg ttgctgaata ccatttatac gcccagttac tgtatcaata atcatcctaa
    15061 gactacgttc tgctgtctct tccattttta aatctataac tgtcaaagga ggaatacttc
    15121 ttgccattag tcgtgaaggt ccattacttg ctgcaaatat ttgaatatcc tctccaatta
    15181 caattccaga ttcatgaaat gcattcatca taccaagagc tacaacatca tgattacaaa
    15241 aaattacttt ttttagtgaa ttttttgcaa gcattttttg agcaatatca tatccactat
    15301 ctattttatt agaacaataa tatatagaat ctgatagatg tattccatgt tctttacatg
    15361 tttttaaaaa agatttaccc cttaaagtca tacatgtaaa ggaagttggg ttgaatacaa
    15421 cagcaatatc atttttacca ttttgaatag catgtaaagc tgctatacga ccagtttcct
    15481 cattatcaat agatacactt gaaaaaccag gtatttcacg atttacaaca actacaggaa
    15541 ttttaggttt attttttact agatattcta tatcatcagc attgatacct gttaaaacaa
    15601 ttccatcata ataattattt gcaaaaaagt attcatcatc acatagatga ccaactttgt
    15661 aaggtcgtat gatgatattt atgtttaaat gttctaaaga aattatgtgg tttattgctt
    15721 gaagtatatt ggttgatgcc aactcaaatc cctcatcctg ccaataaaaa gctattttaa
    15781 tattattatg tttaatagga gtagagcgtt tatatccaag cttatcagct gaatttaata
    15841 taagctcttg tgtatgtagc ggaatcctgc gttcatttcc tttaccactt aagacgtacg
    15901 agacagttgc tgaagaaaga ccacagtctt ttgcaatatc tttgattgtt gccatgataa
    15961 aatcctcctt aaatagttgc ttaaatttgc ttataccaat aatcttaaca tatattcaac
    16021 taaagaacaa tattctacaa ggtgcatatt ttacaggatt agaataaata aatttaaaaa
    16081 aacttcttac ttatgttgac ataatttagt ttataggatt ataatatgct taaataagct
    16141 tattattaac tcaaattaag caaagttaag caggaacatg caatgctagc ttgcaatgtg
    16201 actgtaaagg gggaaaaggt atgagtaagg taaatatatt tgaagttggt cctagagatg
    16261 gatttcaaaa cctgaaagag tttttagaaa ctgataaaaa gcttaagatt attgatggtc
    16321 ttattgcttc agggattaaa caacttgaaa ttagttcatt tgtaagccca aaagcaatac
    16381 ctcagatgaa agatgcaaaa gaagtagcaa cttattgtgt agaaaaatat cctgatgtga
    16441 aactttatgc attagttcca aatttatatg gtgctaaagt tgcatgggag tgtggtataa
    16501 gagatatatc ctatgttata tctttgagtg aaactcataa taaaaaaaat ataaatcgta
    16561 cccatgaaga gtctattgat gagcttaaaa aaataatgaa tacttatcca gacatgaata
    16621 tatgtattgg aatggctact gtatttgggt gtccttttga aggtttacca aaaattgaag
    16681 atgccataag atttgctaaa cgcctttggg aaaacggtat cagggagata aatctagcag
    16741 atacaatagg gattgctgac cctaagcaag taagagaaac tattagtgca ttagttgaag
    16801 ctttaccaga gtgcagatgg caggtacata ttcatgatac tagaaatatg ggaatggtta
    16861 atactcttgt ggctattgaa tctggaatta ctactgttca gtctacactt ggaggattag
    16921 gaggatgccc atttgctcct ggagcatctg gcaatactgc aactgaagat ttagtatata
    16981 tgcttgaacg tatggggtat gatacaggag ttgattttgt taaacttctt gaattatcaa
    17041 agtatcagaa gagttttgta aatggagtat atagtggtca tcatgtaaat ataaagtctg
    17101 atagttgtaa ttgttagttc tattgattaa tcgattaaaa aaatatgttg attaaaaaaa
    17161 tatgctgatt ggtaaaatag atttattgat aaaaaagata aattataaaa tacattatct
    17221 aataaaacaa ataaaaaaat tgagggggat tagtatggat attatagctt tacttttatt
    17281 tttaggagtt attattattg catttgtacg taagaataat gcaggtattt tggctctagc
    17341 tattggtgtc atagctgtta gaatttttgg aatggatgat aaagaacttt atggagctat
    17401 aagcaactca atgtttacta cacttgttgg tataacacta ctctttgcaa tagtgaactc
    17461 aacaggagca ttaaagcttg ttgcagaaaa aattgtagct gcttctggta aacgtgtttg
    17521 gcttatacct atagcagttt ttatagcagg atttgttgtt gctggtgttg gacctggggc
    17581 aattccagca cttgcaatta tcccagcaat ggctgttcct gtagccataa cggttggtta
    17641 taatcctgta atgcttgcac ttataggtga atgtggatta atggcaggtc gtatgactcc
    17701 tattactcca gaaggtcaaa ttataacaac cgttgcagaa ggggttggaa ttgaaaatgt
    17761 tatgcctact atcttagcct gtcaaactct ttctacaatt gtattttcaa tagtattgtt
    17821 tataattttc aaaggatata aacttaaaaa acctataaat gttatagata gtaagcaaat
    17881 agaaaaattt aatataaagc agataatttc tctaataagc atagtagtta tgattgcttt
    17941 tatcataatt tttgatatga atgttgggct tgcagctttt gcagtttcag ctgtacttat
    18001 ttttttcaat attgctgatg aaggagaatg tatcaaatca attccatgga gcacgatagt
    18061 aatggttctt ggagtaggtg caatgatgac aatcgtagat gcagcaggag gtattgactt
    18121 gatgagtaat gcattatcat cactgatgaa tagtaaaaca gctactccaa ttatgagtat
    18181 ttcagcagga cttatgtcta tggttagttc tgctttagca gtagtttatc caactatgat
    18241 gcctatgtgt gttgatatag ctaaggcagt tggaggagta gacccactag cacttattgc
    18301 tgcagtcggt gttggaggtt ctcttgctgg tgtaagccca ctttctactg gtggggcatt
    18361 gattttagca gctatgggtt caagtaagaa agactttaat aaggaagaac aaaataaggt
    18421 ttttgtacag cttttcatta tgagtgcagt tggcttattg gttattgcag tagtatcaat
    18481 attatcattt aatgcaataa cacatttaat gaactaatta taataactga aaataattca
    18541 ttaaatttaa tttttaatat taatcaatat aatataattt ggaggggaag ttatgaaaaa
    18601 aggagcatta agcaatataa aggtacttga ccttacaaga gttcttgcag gtccatattg
    18661 tacaatgatg ttggcggatt ttggagctga tgttataaaa atagagatgc caagaaaagg
    18721 tgatgataca agaggttttg gaccttttgt aaatggagag agtttatact atgcaaatat
    18781 aaatagaaat aaaaaaggta tcactctaaa ccttaaatca gaagaaggaa aaaatatatt
    18841 tttagaaatg gtaaaacatg ctgatgttgt agtagaaaat tacagaccag gtgtaatgga
    18901 aaagttaggt ctgggttatg atgagttggc taaagttaac aatcaaataa tttatggagc
    18961 tgtatcagga tttggatgtt atggaccata ttcagaacgt ccaggttatg atattattgc
    19021 acaggcaatg ggtggtctta tgagtataac agggcaagaa ggaggagaac caacgagagt
    19081 tggtaatgct atgggtgatg tactaggtgg aatgaattta actattggta tactcacagc
    19141 actcaacgct agaaaaataa taggaaaagg acaaagagta gatgtttccc tcgttgattc
    19201 tgttgtatcg tctctcgaaa ctggtataca gagatacttt gattcaggac aacctgaact
    19261 tatgggtaat agatatgctt cagcctatcc ttatgactct tttaaggcaa gtgatggaag
    19321 ttttgtaata ggctgtggta atgacaaact ttttgaaaag ttatgtaaaa aagttctttt
    19381 tagagaagac cttttaatag atgagagatt taaaacaaat cttaagcgtt gtgaacatta
    19441 caaggctctt aaaccagaaa tagaaaaatg gtctgttaag catacaataa aagaagcagt
    19501 tgacttaata tcagaggctg gagttcctgc tgctcctatc tataatcttg attgtgttac
    19561 aacagatgaa catatagcaa aagcaagaga aatgattgta gatattagtc atcctattat
    19621 aggaaatatg aaagtcaatg gaaatccagt taagttgatg acaacaaaag ctaaaattga
    19681 tatgccagca ccatctctag gggaaagtaa cgaggagatt tataatggtt ggcttggttt
    19741 tgatagtgat aaaataaaag atttaaaaga aaatggagtt atttgattaa aaaatagcta
    19801 aacacacttg tgactttagt catgggaggt tcagttagaa taatatcaaa aaatattaaa
    19861 tcaatactgt aaatcaaata tagaattgtc agaagcattt aagatgggaa aagctactta
    19921 gacattgagt ctttgtggct tttcctattt tcattaagaa ctttatatta tcagaataga
    19981 tatgtactaa actaaagtat taacaattta aattaataga aaataaacta cctaattatg
    20041 ttgaataaag actactttag tgaaaataaa cttatagaga tgctatttaa attattttaa
    20101 tggaaatatc aaaaatgaga ctgcattctc aaaaatgaga ctgcgttttt taagtatttt
    20161 ctcgaaaatg agacaaaaat attgttttat gagttttatt gaagaaaaat tcttctgtga
    20221 attacaattt aatcaatttt aaagttgaaa attattaaaa atttagtgaa atttatgtat
    20281 atttcgttta ttttattaaa aataacaatt ttttactaaa aataaagaac ttcaatggtg
    20341 attggcatag tacttgctat tttatattaa caagaaatgt agaaaaaata acaatgtata
    20401 atggggggaa tatgatggaa tctgtaatgg aaaatttgaa caatcttaag gtggaggtta
    20461 aggacaaagt ctgtgttatt actataaata gacctaaagc tttaaatgct cttaatagtg
    20521 acactcttag ggaactatca caagttattg atgtagtatc agaaaatgag gcaatattag
    20581 gagttattat tactggagaa ggtaaagttt ttgtagccgg tgctgatata cgccagatgc
    20641 aaaactataa aagtgaggaa ggcagaaaat atgcaggtta tgctcaggga atttttgata
    20701 aaattgaagc tcttgagaaa acagtaatag cagcagttaa tggatatgca ttaggtggtg
    20761 gatgtgaact tgctatgagt tgtgatatta gaattgcatc agaaaaggct atatttggac
    20821 aacctgaagt taatttagga gttattccat gttttggtgg aactcaaaga ttatcaagac
    20881 ttgttggaac tggaatagct aaagagttaa tttttacggg gagacaagta aatgcagaag
    20941 aagctaaatc tattgggctt attaataaag tggttccaag tgatttactt ttagaagagt
    21001 ctatgaagat gatgaaccaa atagttgaaa aagcgccaat agcaataaga tatgcaaaag
    21061 ttgttattaa caaagggata gatatggatt taaagaatgc tcttgaacta gagaaagata
    21121 ttgcaggttt aacttttgct acaagagata agcaagaagg aatgaatgca tttatagaaa
    21181 agagaaagcc agtttttgaa aataagtagc tattataact aaattggaac aatgtagaat
    21241 atattcaaaa tctaaatttc gtgaaaaaat acatatagtt taattttaaa aggagttaat
    21301 ttatgaatac gggagtaatt ataagtttag tagggattat catagctcta tctcttctag
    21361 ttgtaatggt tatgaaggga ataaatattt ttattatagc aattgtatgt tcatcattag
    21421 ttgctataac aggaagccta aatgtgtatg atgcacttaa agtggattat atgacaggat
    21481 ttgttggatt tcttcaggca aatttcttta ttttcctaac agggacatta atgggaaaaa
    21541 taatggagat tactggtgga gcaaaatcta ttgctaagat gattgtaaga tggattggta
    21601 aggataaagc actactttct attccaatag cttgtggaat attagcctat ggtggagtaa
    21661 gtgttttcgt tgtaagtttt gcagtgtttc cgatagcttt agaaattttt aaagaagctg
    21721 atttgccacg aagatttata ccagcagctt tgacttttgg atgctcaact tttgctatgg
    21781 ttgcaccagg ggcaccacaa attcagaata ttgttccagc atcaacatta gggacagata
    21841 ttatggccgg agcagtaaat ggttttatat catgtgcagt aatgtttata gttggaagta
    21901 ccattttgta caaaatggtt tcaaaagaaa aagccaatgg tggtcatttt atagcacatg
    21961 aatcagatat atttgatgaa gcagaagcaa ctaattctaa gagagaaaat ggtcctaatg
    22021 gtgtaattgc cttaattcca ttgatagtgt caattttaat aattaatgta aaagttaatg
    22081 gaaaagcgat agtaccaatt gaggtgggag tatttattgg agctttatta gtatatttat
    22141 tgttaaataa atatcaagat aatactaaaa tagttggaca tgttggtgat gcatgtaaaa
    22201 ctacagtagt agcaatatgt aatacttgtg ctgtagttgc atttggttca gtagtaaaat
    22261 cagcagttgg ttttgacttc atagttaatg ccatgactaa tattcctggt cctcctattg
    22321 caggggctgc agttggaact acagttattg caggtatttg tgggtcagct tcaggtggac
    22381 taggaattgc agctccactt cttggaccag tatttttagc caagggtgtt tccgctgcag
    22441 cattaactag gactatggca atttcatcag cagcattaga ttcacttcca cacaatggat
    22501 atattgttac tgtaacaaat ggtctgtgta aagaaacaca taaggatgcc tatatgccaa
    22561 tattctgggt aactgtttta actccgttta ttggaaccat agtagcagtc ctactgttta
    22621 caatgttccc gggattgcca taagagaaaa gataaaaggt ataaattata ttttgatatt
    22681 ataaaatcaa ttttcaaaat atatacaata aatttcatgt tttaatacta taaatatgta
    22741 tttaaaataa caaattgacc atataaggag gaattgaaag tgttaaataa accattagag
    22801 ggagttaagg ttattgacct aacgtatttt gtagcaggtc cagggacttc taaaatatta
    22861 gctgattggg gtgctgacgt tattaaggta gagccaagct ttggagaccc aggaagaaag
    22921 acaggggcaa caatgacaat gccaatagat gattataata atccttttta cagcacatat
    22981 aattcaaata aaagaggttt gtctataaat cttaagagtg aaactggaat tgaaattatg
    23041 gataagcttt taagtgaagc aaacgtattt gtttcaagtt atagaacagg agcattaaaa
    23101 agactaggtc ttgattatga atcattaagt aaaaagcatc cacaccttat ctggggtcag
    23161 ataaatggtt ttggcgattt tggacctgct aaggataatg caggatttga tacagttgcc
    23221 ttttgggcaa gaagtggggc tatgcttgat atagcagaaa aagatacaag tccaataaat
    23281 ccacctatag cctttggaga tgcaacaact tcttgtagtt tatctggagg aatatgtgca
    23341 gctttgtacc agcaagctaa gactggaaaa ggacaaaaag taatggcatc tttatttggg
    23401 caagcaatat ggaatgcatc atctttatta gcatctacac agtttagtga tgagtatcca
    23461 aaaactagaa aaaatgctat ttcaccagta ataaattctt atcgttgtaa ggatggaaag
    23521 tggatattct taagtatttt agagcatgaa agatattttg aggcactttg tagattattt
    23581 ggaagagaag acttaataaa agaagagaaa tttgcatctt cagtagaaag taagaaaaat
    23641 gctacagaac ttattaatat tttggatggt gaatttgcaa agtttactca aaatgagatg
    23701 gttgaaaaac ttactgctgc tgatatagct catgaaaaaa ttcaacatgt taatgatgta
    23761 gtgactgatg aacaggctat tgctaataac tatatatatg agcatacaag taaaaatgga
    23821 aataagacaa tgcttgcatc cactccagtt aaatttggaa atattgaagt taacatgact
    23881 tgtgatgctc cacttatagg agaacattca gatgagatat tgagagaact tggatacagt
    23941 gattctgata tagaagctct aattgaatct ggaattgtaa caatgaataa agaagcatgt
    24001 gaaatatgtt aataaacatg tgaagtatgt taataaatag gagggaattt tatggatttt
    24061 agattaacag aagcacaatt aatgcttcaa agagtagcaa aagaatttgc agagaatgaa
    24121 atagcaccaa tagctgctga aacagataaa acaggtattt ttccaaggga gctttttagc
    24181 aaaatggcta aaataggatt taatggcatt ggaacacctg tagagtatag tggttctgga
    24241 gggacagata tagaaaaggt aattgttgtt actgagattg ccaaaaaatg tgcagcatct
    24301 gcagcaatat tatcaataca cacaatatat gctcaagcta ttttgaaatt tggtactgag
    24361 gaacaaaaga aaaaatacct tccaatgatg gctgaaggtg ggtgtgtagg tgctttcgcc
    24421 ttaactgaac ctaatgctgg ttcagatgct gcaagagctg caacaactgc aattattgat
    24481 gaagaaacgg atgaatatgt tttaaatgga actaagtgtt ttatttctgg tggaggtcaa
    24541 gcagaatcat taataatatt tgcactgaca gacccatcaa agggaataaa gggaatgtct
    24601 gctatcattg tcgacaaagg tactccaggt ttttcaatag gaaaaattga agaaaaaatg
    24661 ggtattcatg gttcagaaac tgcagagtta atatttgata actgtagagt tccaaagtct
    24721 aacttattag gaaaagaagg caaaggattt aatatagcta tgacttgttt agatggagca
    24781 agaattggaa ttggagctca agctgtagga attgctgaag gggctttaga agaaagtatc
    24841 aaatattcta aagaaagagt ccagtttggc aagccaattt cagcgttgca aggtattcaa
    24901 tggtatatag cagatatggc gacaatggtg gaatcagcaa aattattagt atattatgct
    24961 gcagatttga aagctagagg agaaaaacac actaaagaag ctgctatggc aaaatacaat
    25021 gcgtcaagta ctgcaagaga ggttacaaat ctagcccttc aaatccatgg tggatatgga
    25081 tatatgaagg attatccatt agagagaatg tacagagatg ccaaaataac agaaatttac
    25141 gaaggtactt cagaaataca caaagttgtt atttcaagag cagtactagg ataggaggaa
    25201 aagaatgaat atagttgttt gcttaaagca agttccagat actaatgaag ttaaaataaa
    25261 taaagagaca ggtactctaa taagagatgg tgtaccaagt ataatcaatc cagatgatag
    25321 aaatgcttta gaagaagctc taaaaatgaa agatgaacta ggagcagtga ttaaggttat
    25381 aagcatggga cctcctcaag ctaaaagtgc tttaaaagaa gctttggcaa tgggagctga
    25441 tgaagcttat ttaatctcag atagagcttt tggtggttca gatacttggg ctacatctac
    25501 aattattgct gctgctatag aaaaggttgg aaagtatgat gtaatattct gcggaagaca
    25561 agctatagat ggagatacag ctcaggttgg accagaggtt gcagaatttt tagggatacc
    25621 acaagttact tatgcaaaag aagtaaaggt tcaagatgac aaattactag taactcgtta
    25681 tacagagaca ggggattatt taatagaagc aaagatgcca gttttattaa ctgctataaa
    25741 agagttaaac aatccaagat atccaagtgt aaaaggaatc ttagaagctt ataataatgg
    25801 agatgcgaag attactgtat taacacttgc agatttagat gttgatacaa ctcaaattgg
    25861 attaaagggt tcacctacaa atgtttataa gtcttttgca ccagttaaag acaagcataa
    25921 tgaaataata gaaggtataa ataaaaaaga aaaagctgag aaactaatag aaatactatt
    25981 cgatttgaaa ctagtatagg agtgttaaga tgatgagagc aaaagttaat caaggtataa
    26041 atttaaatga ttataatggt gtttgggtaa taggggagca aagggaaggc aaaattaatc
    26101 ctgttacgat agaacttatt ggtgaaggaa gaaagcttgc tgaccaatta ggaaaagagc
    26161 ttgaagttgt gatagctgga tatgaagtag agaaagaagt gaaggaatta cttcactata
    26221 gtgttgataa agtatattac atcaatgacc ctcttcttaa agatttcact actgatggat
    26281 atgcaatttc aattgcaaat ttaatcgaaa gaaaaaagcc agaggttgta ttggttggtg
    26341 ctacttctat aggaagagat atagcgccta gaattgcagg taaggttgga acaggtctaa
    26401 ctgctgactg tacaaaactt gaaatagatt caacagataa taagttatta caaacaagac
    26461 cagcatttgg tggaaattta atggccacta ttgtttgtcc aaaaaataga ccacagatgt
    26521 caacagttcg tccaggagtt atggcaaaag ctgtaagaaa cgaatcagag actggaattt
    26581 tagaagttgt tactccagaa cttactgaaa aaatgattag aactagatta gtagaggtac
    26641 ttccacaaga aaagaaatct gtaaatctaa ctgatgctag aataatagta tcaggaggaa
    26701 gaggattaaa aagagcagaa ggatttgagc ttataaaaga attggctgat aaattggggg
    26761 cagagattgg tgcttcaaga gcagcagtag attcagggtg gatagaacat tctcatcaag
    26821 tgggacaaac aggaactact gttagaccag aactatacat tgcatgtgga atatctggag
    26881 caatacaaca cttagcaggt atgagtgatt ctaaatatat agttgctata aataaagatg
    26941 caaaagcccc tatttttagt atatgtgact atggaatagt aggagattta tatgaaatta
    27001 tacctgaaat gatagaatca ttaaataggt aacttttaga aaacattgaa tatgtagaat
    27061 gataagtctt ataatattgt attgtaagac ttattatttt tgctgaaggt tatagtgggg
    27121 agatgaaaca atgaaagagc agtggtataa ggatatattt gcaagaatat tatctatgac
    27181 tgatgatggt tttattgttg taaatacaag tggagtaata atagatatta atgataaata
    27241 ttgtgacttt ttaggaaaag aaagaaaaga tataatagga caaaatatac aaagtattat
    27301 accaaataca aaaatgctag atgttatgaa agataagtac tgtgaagaag gagctataca
    27361 tcattattca ggtggaaata caaaagaaaa aagtgtaata gtaagtaggt cttatgtaga
    27421 aaatgacaat ggagaagtag ttgcaggagt agctcaagtt aaatttagat tgcaatcatt
    27481 tgatgtagct aaaaaattaa tgtcagaata tatggagctc caatattata aagagcagtt
    27541 taaggataac tgcggttttg acaagctcat aggtgaaaat agagacttca tagaacttaa
    27601 gaaaacaggt gtgaaagctt ctaaaacaaa ctttccagta cttttaacgg gtgaaacagg
    27661 cacaggtaaa gaagtctttg ctagagcaat tcacaataat agcagtaggt cagataaacc
    27721 tatggttagt ataaactgcg ctgcaatacc agaagaatta ttagagtcag agctatttgg
    27781 ttatgacgaa ggagctttta caggagcaaa aaagggtggt aaaaaaggta agtttttagt
    27841 tgcaaataat ggtacaatct ttttagacga gataggtgac atgcctttga ccatgcaagc
    27901 aaaactttta agggttcttc aggaaagtga gatagaacca gtgggaggtc ttaaaactat
    27961 aaagatagat gtaagagtaa tctctgccac aagaaagaat ttaagtaaaa tggttgaaga
    28021 gggattattt agagaagacc tatactatag attaaatgta ataaacattc atatgatgga
    28081 attgaaggac aggcaagatg atattttatt gctagcaaat tatatattaa acaaattaaa
    28141 tgttgaatac aaggaattga aggttttaag tgataaggtt aaaaattgtt ttattaacta
    28201 tacttggccg ggaaatataa gagaactaca aaatgtaata aaaagtgcct atgctgtaag
    28261 tgatgatatg gtcattatga tgtgtgacct tccatctaag atggataata tcagcagagt
    28321 agctcaatgt aatgtggata gcaattgttc aattcatgaa atggttgaga attatgaaaa
    28381 aagcttaatt attgatgtgt taaggaagta taattggaaa tgttctaagg cagcagaggt
    28441 tatgggaata cacaagagtc ttttatataa gaaaataaaa aagtatgaaa ttgaattaaa
    28501 taattaagat aacttgaatt aaggcaatgc taaaaaaagc gcccttattc aaagcgaact
    28561 gtataaactg ttttatgcag ttaaaacgtg taaaagtaga tgtgaagtac taatgtcaat
    28621 cattagtact ttttattgta tttataatta ctatctatat ttcagtatct tttgatatct
    28681 aagattatta tgtttaattt aggatataac aaaaccctct tagttattga cagtttttta
    28741 tattttaact gtctactaag aggggatagt ttagtttaaa tttagagtaa attttatcta
    28801 gcatttataa aaaatatttt gaatagcttt tttgttattt agtcataatt ttctacttct
    28861 ttatcaagtt ctttgccaca agaatcacac ttatatatag cattgtatcc ataatcatat
    28921 tcatcaacta ttttcttttg tctaaataca ccaccacact cacataggaa accaattttt
    28981 ataagtgtaa cgataaattg tgattttata aattttatat cattacattt atcgttagtg
    29041 taaaatgtat aaatataaga gttatcgcac tcatctctta attcaaatct ttcaatatat
    29101 gtgttatttt ttaattcctc aaattcttct ttagttaaat atgatttttg ttgcaattca
    29161 tgtaaacgct taatttggtc cattatttat atcctcccaa taattttagt attttaagct
    29221 tagataagga atctaagttt tattaaattt atcccaagga attatttaaa tcatatttag
    29281 ttttattaat tacaacatat ataaattaca cgaaaataaa actaattgta aaaataatat
    29341 cctgtgaaaa cctaaactac taacccctta ctaacccgaa aactaaaaaa agaaaatata
    29401 tccaaatata agtgatatat aaataaagat gttttatata aatttaactt taaatattct
    29461 gacaataata tatataaata tattatagtt aaaatatacc acatattttg ggcattgtat
    29521 actggaatta gagtaattaa tttatttttt aacatacaaa tgattttatg aaaaaaaaca
    29581 agactcaaaa atttttatat tctttgatag aataaaattg agagtaaatt tattgaattt
    29641 tataaaattt ataaggggtg agtctaagat atgcatgaag ataaaaatga tatatttgaa
    29701 tcaatagata ctgaggattt tgataataaa acagaagaag aatgtttaga gctagtaaga
    29761 aaaaatggat tgaatttaat atacataaaa aatcaaacag aagagatatg tctagaggct
    29821 gttagacaaa attgtaatgc aataaaatgt gttcagaatc agacagaaaa aatatgtata
    29881 gaagcagtta aacaagattg gagaatgtta gaatttgtgg aagagtcaac agaagaaatt
    29941 tgcatgttgg ctattaacca agatggaaca gcattaaaat atatagaaaa tcagacagag
    30001 gagttatgct taagagccgt tgaaaaaaat ggtgcggctt tggagtatgt aaaagaacaa
    30061 acagaagaaa tatgtataga agcagttaga aacagcgaat ttggattggc aagagtgaaa
    30121 aatcaaacag aaaaaatatg tatggaagca gttaagcatt gtagctataa tctaaaatgg
    30181 gtagaaaatc aaacagaaga aatatgtatg gaagcagtga gacaaaatgg gcttgatttg
    30241 aaatttgtaa aaaatcaaac agaaacaatc tgtttaagag cagtaagaca aaatggaatg
    30301 gcattagaat ttgtaaagga acagactgtt ggtatatgct taaaggcagt aagacaatat
    30361 ggaatggcat taaaatttgt aaaagaacaa acagaagaaa tttgtacaga agctataaaa
    30421 caagataaaa gagcacttag ttttgtaaaa ggagataagg aaaaatacaa ggctctatat
    30481 gataataatg aaccatttgc aaagagatat gttagaaatg taatagaaaa agaaaacaga
    30541 gcattgatta aaaaaggaga agaaaatgca aaaatcaaaa ttgcaggaaa actttatgat
    30601 agaggcatgt cttttgaaga tatatcagat atagttgaga ttgaaataag caagttaaaa
    30661 gtgagtttag gtgtttttta aagtaataaa tgtaggtgtt ttttatggga aatagttaat
    30721 aaaaaaataa tcgactagct ctttgtagga cagcaaaatt agtgatataa tttgatgtat
    30781 aataaattat ttttattaga taagggggaa ttaaagttga agattacagt attataccaa
    30841 acaagaagtg gaaacacaga aagggtcgct aagctgatag aagatggagc taaaaaggtg
    30901 gatggagtag atgtaaagct tatgagactt gataatattg atttagatta tttaaatgaa
    30961 agtaaagcag taatatttgg aacacctact tatttagcaa atacaacttg ggaagtaaaa
    31021 aaatggtttg atgaagattc aaaaaaagtt aatttagctg gaaaattagg agctgttttt
    31081 gctacatgtg attatatatg tggaggtcca gatgttgcga tacttactat agtaggacat
    31141 ttgatggtta aagggatgct tgtgtattct ggaggtggtt ctttaggaaa gccatttata
    31201 catttaggac atgtacattc aattgaaggt ccagagttac aagatgagaa ggctataata
    31261 tttggtgaaa gaattgctac taaggcaaaa gaactatttg cttaatttct atatgcataa
    31321 taatgattag agtaaattta gggttttaat ggagatttga agtaaaagtt ataaaataaa
    31381 aaattttcca taaaattact caagatgaat tataatataa ttataaataa attatattat
    31441 taaaatattt aaaatcaaac gtcaatagcg agggaagttt atggtatggc atatagaata
    31501 tgagattttt tctgcaatta tagttatttt tttaatggta tactttttta gaagtaaatt
    31561 tatacctact ttacaaaaca aaatatattg tgcactttta atattctcat ttttatttat
    31621 actttcaaat attttaggtt cattttgtct aaataatata gacaaaattc caatttttat
    31681 tactttttta ttgaatcaga tatacttatt gttattgcca ataccagcag ctcttgtatc
    31741 attttatgtt atggctatta tttatcaaga tataaggtat atgaaaaaaa gattattatt
    31801 tttatctata ccacttataa tttgtataat cttatctatt acaaatcctt ttacgcatat
    31861 tctatttgga ttgtcaaaag aaacaggtta tatacggggt tgtggatatg ttgcaacttt
    31921 tgcatctttt ttcttttatg caatatattc agcattttta tcttttaaat atagaaaagc
    31981 aatgcatgaa tcaaaaatat gggctattag aggttttctt atagtttcaa ttgtggcaat
    32041 tatcttacag gcaatttttt tacagtatct tcttacagga actgcatgtg catgtagttt
    32101 acttttgaca tatctttcta tgcagaatcg aggtcttatt attgatgacc ttactggtgt
    32161 actcaataga caatctttta ttcaagagct agatttgaat atcaatactg aacaatcagg
    32221 atttattatt acaattgcgc ttgatgattt taagtttatg aatgaaactt ttggaacaaa
    32281 aaatggagat attgcactaa aagaagttgg aaaatatttg attcagatac atgatgtaaa
    32341 ccatgtatat agaatagggg gagatatatt ttctattgtt gtcaatagtc aattaggtat
    32401 agaaccagat gatattatca gaaagataga agaaagattt aaaaagcctt ggctagtaga
    32461 agagataagt tttaatttag caactagtat tgctgttgtt tattacccag aaaatgcaga
    32521 aacgacagaa gatgtaattg ttgctataga tttctctata catgaagcaa aacgttctga
    32581 gtcaaggcga gttgtttatg cagatgcgtc tataagtgaa aagataaaga agaaacatgt
    32641 tattaaaaat tgtttaaaag aagcattaaa aaatgatggg tttgaagtgt actaccaacc
    32701 tatattttct aatagcaggg gcaggtttac ttcagcagag gcattactta ggctagaaca
    32761 caaagagtta ggttttatac ctcctgatga atttattcca attgcagaac aaacaggatt
    32821 gattaactca attggattag tagtctttga gaaggtatgt agatttatag ctagtgatga
    32881 gtttgaaaat ttaaaattgg ataatatagc tgtgaatctt tctgtagtac aatgtatgca
    32941 aaaaaactta gctgatgatt tactttatct tatgaataaa tataatgtat caccaactaa
    33001 atttaaactt gaaattactg agactgtggc tatgggctct tttaatataa ttaaagaaac
    33061 aatggaaaga ttaattgatt taggtgttaa gtttgcactt gatgattttg gaattgctta
    33121 ttctggagtt actaatatgc tttctttacc attttcagta attaagttag ataagagttt
    33181 gatttggtct atgaatgaag atagtaggca taagcttaca gttgagacga ttatagctct
    33241 tataaataaa ttgaatatga aggctgtagc agaaggtgtt gaaaccatta agtgtgctga
    33301 agatttaata gctatggagt gtgaatattt gcaagggtat tatttttcta aaccagttcc
    33361 agaagatgtt tttaaaaatt tgttgaaaga aaatactttt acaagttaac accctttatt
    33421 tttttaatta caactttgtt cattgacact gccagcgata tattataaaa ttaacacaat
    33481 aataaatatt aaatttatta tacatattat taatattaat taatggagta aagatttatt
    33541 atattttatt taattatcct aaagtgagaa aggaagatgt gacatgaata aaaagaaaat
    33601 attagtgcca attgatggga cagaaagaag tatgcattct ttggaattta taaaaggaat
    33661 atttaaaaaa gatgaagttg aagtagaaat aatgaatgta aaagaactag tatttattga
    33721 tggcatatcc ctggctgaag agataaaaaa ttctgaaaat ttaggaagaa gaatcttgga
    33781 taaagcagca gagataatgg gagagtatga tgttaaagta cattttactt ttggatatcc
    33841 aggagatgag ataattagaa aagcaaaaga agataatgta gattttatag ttatgacaaa
    33901 atctactaaa aaaggtctta caagaatgat aggttcagta acagcaagtg tagttaaaca
    33961 agcaaaatgt atagtgatga ttgtaccgga gtagaattag aaaggtattt gaaatatgaa
    34021 taaaaagata gtagcagttt gtgaaagtga aagaagttta aattctctta agacagctgc
    34081 aaatgattta ggatttgatt tagtttatga aattcaagaa aatgataata taaaaaatga
    34141 actttctatt tatgatatag aagatgcatc tatagtgtta tttgttacaa gtgattctat
    34201 agaaagcata gagaagattg atagatttat agatagagaa ttttatgaag ttgatccaaa
    34261 gtatataata gaggatgcaa aatctatagt aagtgaaatt ttaatagact taaattaatc
    34321 gtgggtgtcg cactaagaat agagcgacgc ctttttacat attttacata agaaataaag
    34381 ggctgtctca aactatagat aagactcttt ttcattgttg aaatgatgaa aatatatttg
    34441 atttcataca aaaaagagtg cctcataact aaaaagttca ctttgagaca ctccattttt
    34501 atatgttagt tgcatttaag gtaaaataga agtttaatca tgttgaaata actgaattac
    34561 atcttctaaa tgattgtaca ttgatgtata acctaagtaa gagtctttac tatcaaatgc
    34621 catcattatc ttgttatggt ggctaatcat atccttaaga gaatttctat atttaaaacc
    34681 gaagtattgg ttagaagaaa ctgttttagg tattaactca taatatttta taaaaattgg
    34741 attatgagaa gctaaaatta tctctttgtg aaattgtaag tcagcatcat aacattcttc
    34801 tatcaaacca tgagaaacct tatccaattc ctctattgac tttaggtaag tatattttat
    34861 tttttgaagt tctttagatg tagcatttaa aattgctagt ttagtagctt cactttcgat
    34921 aagttgtctt gctcttaaag attctacata aaattcttgt atgttatgat ttttatagat
    34981 ttcaccatca tcaaataggt caactttttt aaatccttca actataggac ttgagtaagg
    35041 cacagctcta agtattcctt ccttacagag tatatttatg gcatttctta caggtattct
    35101 acttatgtta aataggtcag caatctttct ctcacttggt aatttactat taattttaaa
    35161 agttccattt agaatgttta atttaatata atcaataatt ttttcagtgg catttaagct
    35221 tttcataaaa actcctaaac atataatttt tttatgattg tattatatca tagttaagag
    35281 ttaaatctac ttttttataa tatgtataag acaggataga ggccaaaata gctataatag
    35341 ccaagataaa gtatccatat tgtattgaag tatattccga tattttacca actatcattg
    35401 gaaatacaga cattcctata gcataaattg cttgaaaaaa acccattgca gtagatttct
    35461 gatgttttgg tacatttttc atagactcgc tagtaaggta agaaaggagt atacctgtag
    35521 atatacctgg tagcacttgt agtacaaata ttatattaat attttttatt gttggaacta
    35581 aaaagcaata ggctgaaact aaaataaaaa ctaaaggaat ccaaaatttt ggcccatact
    35641 tagtacaaaa tttagtagaa gcaaagccag aagaagcaac agcacacacc atgtaagata
    35701 tagaagatag acctatgagg gtagaactag aacctaagtt tttaagaatt tgagtagtaa
    35761 atgacattgt tgtagacatt tgaataccct gttgaattaa tgccataaag gaaaaaaata
    35821 caagtctttt atctttgcag atagataaat attttttaat tgatattttt tcaggtattt
    35881 tttttgaatt atgatttttt atatttaagg ctagaatcgt tccaataact gaagacaata
    35941 cactcatgat acataaggct gtcattccta atttttcata aaataaagta ctcataacaa
    36001 atccaatcaa cattcctaga ttgtttacca atattatcgt actcgtagct ttttgttgat
    36061 gttctgtaga aaaaaagttg gtatagtgaa ccatgtaaga aatccaagtt gatgatgata
    36121 ttccagataa aatgttagct ataagaaaac cattgcctcc aggagaaaag actcttataa
    36181 gagatgctaa accagcaaag aaaattccag acagtataaa tattttatgt ttatttatag
    36241 aatcagcaaa tactccaaca ggaatcctta ataaacattg tgagattcca tatgcaccta
    36301 ttattatacc aatcatattt gtagatacat tacatgcact taaatatgga ttttggaaag
    36361 gtatatatac atattgtgaa aaccagaaaa atgtaacaat agaaagtaaa agtaattttt
    36421 gattagatat ttttttcata ttatcctcca tatggtattt ttataatgca aataatatac
    36481 catttagatt ttttaatcaa gtactttctc tattaaaaaa aatttaaata tataattatt
    36541 atttacaaaa aaattatact ttatagttga attaagaaaa cgcttatgat actataaagt
    36601 taacaaattt gaatatataa cagtagacgt gttactggta atgcaggcaa gatcgaatca
    36661 atttttatag attatctata gagtactatg ggtataatct atttatttgg ttcgattttt
    36721 ttgtttaatt ggccataaaa caaaaagcct atagttgaaa atggaggatt ttttatggat
    36781 tataaaaata tagctcaaga aattctacta aatgtaggag gaaaagagaa tgtaaatgaa
    36841 gtgactcatt gtatgacaag acttagattt aaagtcaaaa gcgcttctaa agtgaataag
    36901 gataaattat ctaaaactga aggagtaata actgttgttg agagtatggg tcaaatacaa
    36961 gttgtaattg gaaataaagt aaaaacagta tatgatgagg ttataaaaat tgtacctcaa
    37021 tcaaatgacg taggtaaaaa gaatgaaagt caagaaaagc aaagtataat taattctata
    37081 ttatcagcag tagctggtat atttacacct acaatacctg ctatagcagg ggttggtatg
    37141 attaaaggta ttttatcagt tcttgctatg tattatatga ataaaaatgg agtagatata
    37201 aaagaaacgc aaagttatat tatcttaaat gccatggccg attctatatt ctattttatg
    37261 cctattatac taggatatac tgcggctaaa gtatttaatg caaataaaat aatatctatg
    37321 gtattaggag ctacactttg ttatccaact tttactgctt tgatggcagg tgaagaatct
    37381 gttagatttt taggattggc agtaacaaaa gctacgtata catcatctgt tattccaata
    37441 attattgcta tatgggctct ttcatacgtt gaaaaagtat tagaaaagta tatacctgag
    37501 gtaattaaaa taataatggt tccaacttta tcattggttg taatgttacc tgcaacatta
    37561 tttttatttg gaccaatcgg aatttatata ggaaatgtca taaacttttc ttataagtat
    37621 atttatgaat taagcccagc gttgtgtgga gcatttgtag gtgggttatg gtgtgtgttg
    37681 gttatatttg gtgctcatag agcattatta ccaataggta taagtgatgt tgctcaaaca
    37741 ggaagacaga atttattggc atttgcagga gctgcaaact tttcacaagc aggggctgct
    37801 ctaggagtat tctttaaaac taaaaatcaa ggactaaaaa caatttctat gtctgcaact
    37861 ataacagctt tatttggtat aactgaacct gcaatatacg gtgccaatct tagattaaaa
    37921 aaacctatgg tatgtgccgt aatatgtggt gcatttggag gtgcgataat gggaatgggt
    37981 ggagcttatg gtaatgcatt tgcaaaccaa ggtgttttaa ctatacctgt atatgctgaa
    38041 gcaggtgcat taggtttctt aagttatcta ggtggttgtg ctatagcatt ttttggttca
    38101 gctatttcaa cttatctagt tggatttgaa gatttggaag agtcttctaa taaggaaaat
    38161 tcatttataa aagtagaaac gaaggatggt gttattgata taacttcacc tgtagagggc
    38221 gaatgtatag aattgtcaga agtaaaggat gatgtatttg cttcaaaagc tatgggagaa
    38281 ggtatagctg tgttacctac aaaaggagta ataacagccc ctactgattg tgaagtagct
    38341 tctttatttc caacattaca tgcaatagga ttaaaattag ataatggagc agaaatgtta
    38401 atacatgttg gaatcaatac agtagagtta aatggtaaat actttacaaa acatgttaat
    38461 caaggagatt tagtgaaaaa aggtgataaa cttatatcgt ttgatataga taaaataaaa
    38521 aaggctggtt atgatgtaac tacgccagtt atagtaaaca atacatttga ttttgggcaa
    38581 gtagtttctt gtaaatctag ttatgtttca accaatgata atataatttc attagtatta
    38641 gctggtaatt aagttaattt gactagagat aagtaaattg atttaaaagg aaataagtaa
    38701 atcaacaatt aaatacatct aaaagtaagt ttattgcaat gaattgttaa agaaaataat
    38761 taatatggag taaagctatt gcaatgaagt aacaaagaaa ataattaata tagagtaagt
    38821 ttattgtaat gaattgttaa agaaaataat taatataggg taaatctatc tcaatgaaat
    38881 aacaaagaaa agagttaata tagagtgaac ttattgcaat gaatcaacaa aaaaaataat
    38941 caatataaaa aggagaaata tttatgaata caggatttcc aaaagacttt ttatggggag
    39001 catcatcttc tgcatttcaa gtggaaggag cttgggataa agacaataaa ggaaaaaccg
    39061 tagccgacta taattctttt aaaaagtctc atttacaggc agatactaaa gttgcatcag
    39121 acttttacca taattatgaa gaagatattg aattaatgaa agaattaggg atgaaaacat
    39181 atcgtttttc aatttcatgg gcaaggataa taccagatgg tgaaggagag ataaaccaga
    39241 aaggtttaga cttttataat aagataatag acaaactaat agagtgtgat attgagccat
    39301 tcgtaacttt ataccatttt gaccttccat ttaaattagt agagaaatat aatggttggg
    39361 aaagtagaga aactgtctat gcttttgaaa gatttgctaa aatatgcttt aagcattttg
    39421 gagatagggt aaagtattgg caacctcata atgaacagaa tttaattgtt agagtggagg
    39481 agagaattaa tatatatgat gaaacagatt catggaagat agataaaatg cgtgctcaga
    39541 tggattataa tctttgctta gcacatgcat tagcagtcaa tgcatgtcat gagatgataa
    39601 aagaaagtaa aattggagca gcagtatcat catctgtaac atatcctctt acttctaagc
    39661 cagaagatgt atatgcagct agaatgaatg ataattttaa agtgtactat atgcttgata
    39721 tgcatcatta tggagaatat ccagggtatt atatgaagta tcttgaaaaa agaaatacag
    39781 ttcctcacat ggaagatggg gataaagaga tacttaaaaa agctaaaatg gattttatag
    39841 ctgtaaatta ttataggaca aattgtgcag aagctttacc tgaagattca caacatccat
    39901 ttggattaag agaaggaact gttgatttta gtatgtatgg actatttaaa atgtcaatga
    39961 atcctaactt agaggcttct gagtatggag cagcaataga cccatcaggt cttagagttg
    40021 ccttaaatga atattggcaa agatatcact tacctgttat aataacagaa aatggtctag
    40081 gagctaaaga tatattagaa gatggaaaaa ttcatgatga ctatcgtata gactatttaa
    40141 gaagtcatat aaatgcatgt aaactagcta ttgaagatgg tgtagagatg attggatatt
    40201 gtccatggtc atttacagac cttttaagtt cttctcaagg ttttaataag cgttatggac
    40261 ttgtttatat aaatagaact gaccatgaag ttttagattt aaaaagaatc aagaaagata
    40321 gtttttactg gtataaagaa gttatagaga acaatggaat agtaaaataa acataaatat
    40381 atattgaggg ttttagtatg tacattacaa aggtattaaa taattcgttg ctacttgcaa
    40441 aggatgataa tgatgaagaa ataatattga tggggaaagg cattggccat aattataagg
    40501 ccgggtctga gttaaataaa aaagatatag aaaagatttt tgttcttcat gatgaaaata
    40561 taaaaaagag tattatacaa ttggcaacag aaatagatgc agaatatttt ggtatagctc
    40621 aaatgataat tgcatatgga atagaaaaat ataacttaaa acttatgaac catatatatt
    40681 tggccttaac tgaccacatt gcctttgcag tgagacgctt taaagaaggt ataatgattg
    40741 aaaatcacta tttgttcgaa atcaaggaat ttaatccaaa agagtatgat ataggaaaat
    40801 atgctattac tgtttttaag gaggttcttg gtttagacct accagaagaa gagattggta
    40861 atatagcagg ccattttata aatgcacaac aagataatcc ttatagtgat agaaataaga
    40921 gaagtgctaa aattgtaaat gctattttgc aaatagttca ttatcacttt tctattgtat
    40981 ataataaaga gtcattttat tataggagat ttgtaatgca tctaaaggcc ttttcacaaa
    41041 gatttctggc taatgaacca tcaagagaaa aaatagattt tatatatgag caagttcaaa
    41101 aaaattgtaa ggaagagtat gaatgtgtga aaaaggtagg agcttatatg tataaggaat
    41161 actccagaga attaccaaga caagaggagt tatatttgat gattcatatt cataagattt
    41221 taggagaatt atgcgaaaat agttagaata tcttaatatg ctagtaatat tataaaaaat
    41281 taaaaattaa ctacacttta aatatgaaca attgcattac ttaagggggt tgtcttaaaa
    41341 ttgatttttt taattaaatt tgaagctcaa ctcctttttt aaacctttat atcattacaa
    41401 ctttaatgtt tatacgcctg tactttagat gtatatctac tttttacatt tctcaacatg
    41461 caaacctacc attttttgca gtatgttaat tgaaataaac cattgagtta accctaaatt
    41521 tattctggac ttataggaat agttccaaag atactttaaa atattttctg gaataattgc
    41581 ttatttcaca tatgttttat tgtgatgttt tgatttaata aattcttcaa ctctgtatat
    41641 agtaaatgta ttatcatgtt tgttttattc aagcacactt ataatacgct tgattttttc
    41701 acaatgatga aatatactaa tgggtgttat aggtataaga atcgaattac acttgaagaa
    41761 gtaagtgata aatgagatat aaatcctcat atgataaact actatttcat tgaggaacat
    41821 attctaagtg atgtcaagat actacaatat gactaaattc ctagtgataa aaaagtctac
    41881 gaatgagtgt agaaagggga actaagatga ataaagtttt aattatagat gatgataaag
    41941 atctttgtat tttgttaaaa aagagtattt caattgaaca gattgaagca aactattgcc
    42001 attctgggag agatggactg gttgaacttt caaaacaaga ttatcagtta gtagttctag
    42061 acgtgatgat gccaggtatg gatggttttg aaactatgga acaaatacga aaatatagca
    42121 gtattcccat cttaatgctg acatcaaaaa gcgataatta cagcaaagtg catggattgc
    42181 gagctggtgc agatgactat ctaaccaaac catttgaaat tacagaattt actgctcgtg
    42241 tactgtcttt aatccgacgt tacacccgtt ttaatccaaa aaatgaggaa ccacagcaac
    42301 tttctttcaa aggtttgttg attgaccttg accagcatac agtgactacc aatggcgaac
    42361 ctatgttgct tccacccaag gaatttggtg tgcttcttta ctgtgcaagg catcagggta
    42421 agattttgac aaaacagcag atttatgaag ctgtgtgggg tgagccatat gtatatgatg
    42481 acagcaatat catggctatt atcagtcgcc taagaaaaaa aattgaacta gacccatcat
    42541 ctcccatcta tttgcaaaca ataaaaggaa ttgggtatca attcaacacg gaggtatgaa
    42601 aatggatgaa caaacgataa ttcttttctt attcttgctg tcgattggtc tactttttct
    42661 ttccatattt gctttttcca agcttgggca tattcacaaa cgcctaaaag atatagagga
    42721 gatactggct gatgtacaaa ttggaaacga aaatcgcaaa atactaatta agccatgtga
    42781 tgttatggct ccattggttt atcagcttaa tgagattgtc tacgattatg aaaataagtt
    42841 actttctctg aaaaagtcgg ataaagctag caaacaactt atgacaagtc tatctcatga
    42901 tgttcgtaca ccattaacaa ctctgattgg ttatctggat gctgtacaca gtggtatagt
    42961 tatcggacaa gaacgggagg aataccttga aatcgctagg cgtagagcct acgacctcaa
    43021 ggattacatt gatgttcttt ttgactggtt tcggttgaac tctgatgaat ttacgctgtc
    43081 aatagaatct gtggaaattg cagagttgtc acgcaatatt ttgaaagact ggattcctat
    43141 attccatgaa aagaaactga attttgaaat tgatattcca gaaaatcgac taatggtaaa
    43201 tctcgaccca gatggatatt cccgtgtggt taataatctg gttcaaaatg ttcttgctca
    43261 cagtaaggct cggcaaatca agattaccat gagtgaggat tccagaatgg tattactccg
    43321 tgttgatgat gatggtgttg ggattgccag agaaaattta ccacatattt ttgagcgact
    43381 gtataagtgt gataaaggac gttcagaaaa aggaagtggt cttggtctat ctattgtcag
    43441 tcaaatggtg gagcgaatgg gtggtcagat ttccgtagaa agtgagattg gaaagtatac
    43501 cgtatttaca gtgagcttac cattaatata aaattgtttt tcccccatgt gacatgtata
    43561 cacaggggga ttttttgtaa gttataaagt tgcaaggtta atacaaggtt gttgcaaggt
    43621 taatgtaaga ttgaggtggt atgatagctt taataaacaa aggaggattt tattatttat
    43681 gaataattta attattgaaa caaaaaatct cactaagcaa tatggtgctc aaaagagcgt
    43741 ttctaatttg aatattcacg ttcagaaagg tcgcatttac ggattgctag gaagaaacgg
    43801 tgcgggtaag acgacaacta tgaaaatgtt attgggtcta acaaaaccaa ctactggaga
    43861 aattaaaata tttggtcagg acattcacaa taacgagaag aagcttcttc ctcgaattgg
    43921 atgtttgatt gaatcaccag ggttttatcc taatctgaca ggaacagaaa atctcaaaat
    43981 ctttgcaagg cttagaggaa taccaaaaaa aaatgcagta gaatcagcac tggatgtagt
    44041 cggtttgcca aacaatgaca aaaagttatt ttctcaatac tctcttggta tgaaacagag
    44101 gttggcgatt gctcttgcca ttatgcatga cccacaactg ttgattttgg acgagcctat
    44161 caatggactt gatcctattg gtattgcaga agtaagaaag tttattcgtg atctctgcac
    44221 agaacgaggt aaaactattt tgatttccag tcacattctt tctgaaattg ccttgttggc
    44281 agatgacatt ggtattattg accatggtat tttgttggag gaagaaagtc ttgcccaatt
    44341 agaagaaaaa aacagtaaat acatacattt tgctgtatct gatgcagcac atgcagcaag
    44401 gcttctggaa acccaactta acctgaaaaa tttcaaagta gcagataatt acaatattat
    44461 gctatatgat acagatgttt ctgttgcaga aataaatcgt gctttcattc taaacaacat
    44521 tgaggtatca gaatctcatt tatgcgaaga tactcttgaa gattacttca agaaagtaac
    44581 agggggtgaa ggaattgctt gatataattt catgtgaatt ttcaaaactc aagcggttaa
    44641 aatttatact gatttctatt ttaggtgctt gcttatttcc aattcccgca acaattttga
    44701 ttgcaaagga caacttgccc tttgagcaat tgttcaaatt agttgtcaat tttggatatt
    44761 ttttgctatt accaattgta ttaagtattg ttgctagcca actatttttt atagaaagag
    44821 ataacgatgt attaaaaaat cttgcaacag tgccagtgcc aaaaggaaaa ctggctctgg
    44881 caaaattggc tgtgttgctg tttatatcat tgttctactc cgttgcaggg ttaggagcta
    44941 ctatcattgg aggtttcatt gttggaatag tagagggggt tactgtaaaa ttaggaatga
    45001 gcattgcttt tggaattatg ttttttgtta ctgtacttcc tgttgtggta ctcattgtat
    45061 atttcaatcg cagctatatt ttttctatta tactttcttt tgtatatgct attttcaatt
    45121 ttagtatatc cttaaatatt atcaattttg aaccaaataa cccactatta agcgtattac
    45181 ctgctcctgt tataatgcgt tggtggatgg cattttgggg agatcccact ggcgaataca
    45241 cggcacttag acagccatat ttgctctcaa ctcctgcttg tgtaggtatt ttatgtttga
    45301 taaccattat agcagtcctg ctgatttgta tgatatacaa aaagcaggag aattaggagg
    45361 tatctatgct tgatataatt actacagaat ttcaaaaaat aaaaagatat aatattctat
    45421 ggattggtgt tgttgctgtt ctgttttcag cactattggc agtttttcag gttgtaagtt
    45481 cacacggcag tgaccctcta acgtatgaga gctttgcaaa cggagttatc tggaataatt
    45541 tcagtcttag ttttccattt gggattacac ttattggagg atatcttatt aaccgtgaat
    45601 atacagacca aaccttaaaa aacatcctaa ctgttcctat ttcattacgc aaattgctag
    45661 tgggaaaatt aattgcggtt ggaggaattg ctgtattgtt aagtcttttc agcttcttat
    45721 gcacatttat tttggggttg ttattttgca atatcaatat atctgttaca ctcattgtaa
    45781 aatccttagt tcagattttg tctgttaatc tgtattgtta tgttgctgtt ttgccgatta
    45841 ttgcttattt tggtcgtaaa caaaatgcat ttctgacggg tgtagggatt gcatttgtat
    45901 acgggttttg tggtgtgttt gttgctggaa gaaatctgac agacttttat ccaatcacag
    45961 caggtcttgg tctagttgga tacaacaatg gtgctggtac tgtttatcag ccacttatcg
    46021 gtgctatgac tttgattgta attctaatct tgacaactat tctacttgta tttacaccta
    46081 attatgataa agttatgacc atatctaaga aaaaagggat aaagcataaa aagtattctc
    46141 ataaataaca taaatattgt ttctattatt taagttgcta gacagtgaaa agaaaaaatc
    46201 tgtcgtacag tggctatatg ctcatgtatt caagaagcta cagttttgat ttttcataac
    46261 tgtagcttct ttttgtattt attaaatcac ggctatcata atacttgcaa taggtatagc
    46321 gacaagagag agtactgtca tgtgtgtttt atatattaca ttaagtatat tctaaaatat
    46381 atgttttaaa taatatattt gaaaatagga atatttaaat aaa
//
LOCUS       DAMJWO010000021        46205 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.022, whole genome shotgun sequence.
ACCESSION   DAMJWO010000021 DAMJWO010000000
VERSION     DAMJWO010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46205
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.022"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(168..593)
                     /locus_tag="PC366_001254"
     CDS             complement(168..593)
                     /locus_tag="PC366_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012201185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2576788.1"
                     /translation="MHDELKIKMYSFTMDCKDPHELAKFYAALLNWEIAFYNEEYACV
                     GAPGTNQGTYPGITFQRNSEYKPPVWPEKPESQQQMAHMDFAVNDLEEAVQYEIHCGA
                     TIAEEQFTDDWRVMIDPAGHPFCLCQMKSIMESSHFSLL"
     gene            complement(746..1207)
                     /locus_tag="PC366_001255"
     CDS             complement(746..1207)
                     /locus_tag="PC366_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HDF2576789.1"
                     /translation="MKFGGVLLIVKDINKSKKFYEDVMEQKITLDLGEHVSFENGFGL
                     QSNYKAIIGYDLPIYQQSNNFQLYFEVNDIKQWESKINRIGNIEFLHYIKEYPWGQRT
                     FRFYDFDKNIIEISESMESVIKRLLKQGLALEEISKRTMYPVEFITQFQQL"
     gene            complement(1245..2078)
                     /locus_tag="PC366_001256"
     CDS             complement(1245..2078)
                     /locus_tag="PC366_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2576790.1"
                     /translation="MLKKESIHFINKNRSLIVCEDNFVYLLPCMQLKNWISNFTISFP
                     NQTIISDNYTIIPHGSVTLVFFYDATGLHSLLFGPTTKPKTVGNIANRCDVILIIEFQ
                     PAGFFPLIGIQQSELIDKVVPFSIINTSLDLEIKKIFNESLSIDKLILKLEELLISNI
                     KIEYSYEFILAIQLIIQNSGNISSQEISKKVFYSSRHLNRLFNQYLGLSMKSFSRLVR
                     INKSIKLLNNNKTSLMYICNELGFYDIPHFIKDFKIVCGITPQKYRANMSDFYSEIAK
                     F"
     gene            complement(2351..3037)
                     /locus_tag="PC366_001257"
     CDS             complement(2351..3037)
                     /locus_tag="PC366_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2576791.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILDIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALVGKPEILFADEPTGNLDSKTGIEIIDLLNKINRDNGQTIIMVTHSPEAAKSSSR
                     TITVSDGLIV"
     gene            complement(3052..5529)
                     /locus_tag="PC366_001258"
     CDS             complement(3052..5529)
                     /locus_tag="PC366_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2576792.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMYGTATISVQSKNPDVLTNLEDIPDLNAIKSKVGVLESSAIYNKGGYYE
                     EFSLISADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRNTRGVNALLPKETLSKIINKGSGYTRVLIESEEEMTENL
                     VNKLSEELSTEKYMVSNTINETKIISDARQKTMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTRILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPVVISPIGVIISVIVAIIVSSFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSILLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGKMNEEFIENVRHMDGIKKILPLYVMNNEISGNGVTLSRLEGTDNIKLYNSM
                     FGINYTNFEIKKQVIEAFNDKRSVILNEDTLKKVGLSIGDTITLSNDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDVVMIQIRDLFGDTYNWSRTVE
                     EFNNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKKRSIAMYKSIGLSDK
                     QNIKVTLIEGFTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            complement(5749..7152)
                     /locus_tag="PC366_001259"
     CDS             complement(5749..7152)
                     /locus_tag="PC366_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2576793.1"
                     /translation="MHKPSYKTVFHSYIIFFMIFICLILTVIGIFLSLITIQKPNGEF
                     IRSDWPKKFTENFNEQIIFIDNKPQVKQSGLEKLRENQLWLQILDSSGNRVYGFLEPK
                     EHKDYYSNSELLTLANQNNSSNGTVYFNTIKNNKNDYIYIIYFPLNISKVNMFFDGSK
                     FVGGKSIVFSIIGIIFLIILISGIAYGYWVTKCISNITSAVSDISKRSYLPVNIKGVF
                     ADIYNSLNILNEEIHRSDEIQNKTDIMREEWISNITHDLKTPLSPIKGYAELLTDSST
                     NYSPEKVYKYASIMLKNIEYTNTLINDLKLTYQLKNGIIPLNKNKYDLVRFLKELSID
                     ILNYPEYESNIVEFKSNIDNINFDFDCTLLKRAFSNLIVNAFTYGDKNTKVCVHITLN
                     ERIEIIISDNGKGMSREEASNLFNRYYRGSNTKQKIEGTGLGLAITKQIIEVHGGNIS
                     VESIPGLGSSFYITFPI"
     gene            7651..8511
                     /locus_tag="PC366_001260"
     CDS             7651..8511
                     /locus_tag="PC366_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2576794.1"
                     /translation="MKKQKSPILLEMLGLFLGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            complement(8751..9308)
                     /locus_tag="PC366_001261"
     CDS             complement(8751..9308)
                     /locus_tag="PC366_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2576795.1"
                     /translation="MSDSEYPQMKTLETRSCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKRDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(9498..10385)
                     /locus_tag="PC366_001262"
     CDS             complement(9498..10385)
                     /locus_tag="PC366_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2576796.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENEKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            10504..11703
                     /locus_tag="PC366_001263"
     CDS             10504..11703
                     /locus_tag="PC366_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HDF2576797.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            complement(11897..14452)
                     /locus_tag="PC366_001264"
     CDS             complement(11897..14452)
                     /locus_tag="PC366_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2576798.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKKNKKSKEYIVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETAMEGFVNDYLQPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     TYINWPLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIGVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILIAVRVVHQLNKYSSIESMKNFKITNKKK
                     RILESVKHSNMTKVLSHKYMTQKRGMFIGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNVEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKTMKPTGEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFDIENYNSVSIKKTEDSNS
                     EELSENIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFLLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINTPLYIGMIILNITISIVAVIIPVRQILKSDIISEINKS"
     gene            complement(14449..15135)
                     /locus_tag="PC366_001265"
     CDS             complement(14449..15135)
                     /locus_tag="PC366_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2576799.1"
                     /translation="MSILVTNNLVKHYGKGETKVKALNGVSIEIERDTFTAIVGTSGS
                     GKSTLLNIIGGLDNPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     VVVNTGGEVL"
     gene            complement(15212..16120)
                     /locus_tag="PC366_001266"
     CDS             complement(15212..16120)
                     /locus_tag="PC366_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2576800.1"
                     /translation="MFILAFIICTVVIFIVSTKINQRRYDELNLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKSEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKSEAKNIRINLEPFSDIKLVHNKKWTIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVENQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            complement(16122..16793)
                     /locus_tag="PC366_001267"
     CDS             complement(16122..16793)
                     /locus_tag="PC366_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2576801.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGDGFDVCQIIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKACLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDDNIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            17055..18119
                     /locus_tag="PC366_001268"
     CDS             17055..18119
                     /locus_tag="PC366_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S ferredoxin"
                     /protein_id="HDF2576802.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEINLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            18277..18963
                     /locus_tag="PC366_001269"
     CDS             18277..18963
                     /locus_tag="PC366_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2576803.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKENYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINLFKQKVKAFLNHLTTKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMG
                     YMWLGERNEF"
     gene            18953..19984
                     /locus_tag="PC366_001270"
     CDS             18953..19984
                     /locus_tag="PC366_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2576804.1"
                     /translation="MNFKKFSFSSIYLIIAVGIIFTAILFNISIYLITDDLKLIALLL
                     IYTIVLCGFIALIIFLLHKKIVIFCSKICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDLSHQIKTPIANLKMINTTLLNQTFKTEIQK
                     DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTNSNGKIRVATECWVMYTKIDII
                     DNGKGISESHQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGS
                     TFSIFLPNK"
     gene            20066..20731
                     /locus_tag="PC366_001271"
     CDS             20066..20731
                     /locus_tag="PC366_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2576805.1"
                     /translation="MSILQVINLKKYYGQSSNITKALDGVTLSIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMTDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKDFINEIINMLSLEEKLYDMPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGSLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            20744..23161
                     /locus_tag="PC366_001272"
     CDS             20744..23161
                     /locus_tag="PC366_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2576806.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKAKNILYKDKNLSGVGTYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGKLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIVGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESRPDTVDVLV
                     KLSEENTEKDSASIKTQLKKIGLSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLKKTISLQGNILSIIFIPLGAI
                     ASCIIAYIIQPLAWQMIADLFIILILSLVMFLTVRISLFKPARIISKISAIEAMQYTE
                     TKFRKQAKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYEHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIEPYIKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     SYGLNLKVGDTVTFNIFSGNDIIKKKMKIIGIIDNSNTGGMFFASDKTLESLTPYNTN
                     LDFSILIDKKHSKEVEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLRNMLYREGLNISIKAICTSSI
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLIRNIEKKSL
                     TERLRSQ"
     gene            complement(23342..24133)
                     /locus_tag="PC366_001273"
     CDS             complement(23342..24133)
                     /locus_tag="PC366_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2576807.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYIDKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFHKNTQSNENISITQGNAMDLSV
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFAAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSAFNVTRLHYVASDGL
                     ALYMREAVDSMDDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(24166..24753)
                     /locus_tag="PC366_001274"
     CDS             complement(24166..24753)
                     /locus_tag="PC366_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2576808.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNQYVVNYRNSKSVSPYLLLPLSYIEFAQEETYLFKL
                     LFINDLDLMMKEANDFYKEIDNEKKARLFSESIGIELECAKVIFLDLFLYTHGIAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKPDWNLSI"
     gene            complement(24930..26321)
                     /locus_tag="PC366_001275"
     CDS             complement(24930..26321)
                     /locus_tag="PC366_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HDF2576809.1"
                     /translation="MERLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFN
                     PKGRFDSYPISITVGILVACFVMFSERFDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSKEIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSVMLFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIFSPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSVFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCNTGVEKGLIGLMGGVIAAKGGTWGLAVGFILYFILIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            complement(26511..27809)
                     /locus_tag="PC366_001276"
     CDS             complement(26511..27809)
                     /locus_tag="PC366_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase/BAAT N-terminal
                     domain-containing protein"
                     /protein_id="HDF2576810.1"
                     /translation="MKVNVYNVESFVDERLKIMVSDLIPNTKLKISVKMEFPWCKGEE
                     FSSYGVFCSNEKGEVDLDLVEPIEGTYKADNCMGLIYSLEKSKTEGKNFAENISIDKP
                     IIMNMIFETSTERKEVELKRIFKSEDITTKYISDEFIGKLFYKQNSNNKTILMLGGSD
                     GNLDALDLLAAPLASRGFNVLTVAYFALEGLPDKLEEVPLEYFEKVFEWISENEITST
                     KEIFVHGTSKGGELAFLLASRYEQIKKVVVSQPHIYCFQALNGLMSGNDTSSWSYKGE
                     PFPYIKVDNDIFFEEQKKNISKGIPFGFNSTYKKSLKRAENRKEARIKIENSKADILM
                     IAGKEDNIWNSYEACLEALEIFEENNYPYNVELLTYNNMGHPLPIPYIMPLKETLCMS
                     MSGGIFSSGGTVEGNSKGQFESWNRTIEFYKKLLSSDLNN"
     gene            complement(28170..29045)
                     /locus_tag="PC366_001277"
     CDS             complement(28170..29045)
                     /locus_tag="PC366_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HDF2576811.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLN
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDIDTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTIKKMSNYLYNDCFKIHYAVVDALIENRITA
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIKEYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
     gene            complement(29238..29924)
                     /locus_tag="PC366_001278"
     CDS             complement(29238..29924)
                     /locus_tag="PC366_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HDF2576812.1"
                     /translation="MFGVIANSLAIAGGCIVGLIIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(29973..30506)
                     /locus_tag="PC366_001279"
     CDS             complement(29973..30506)
                     /locus_tag="PC366_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HDF2576813.1"
                     /translation="MSDLNNKKEQDENESSMNETKIYDILDKLNVEYDVVEHEAVYTA
                     EQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFASP
                     ERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVIKEDYLNFHPNINTKTVNISRKG
                     FEEFLEYLKYPIQSIDA"
     gene            complement(30550..31182)
                     /locus_tag="PC366_001280"
     CDS             complement(30550..31182)
                     /locus_tag="PC366_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HDF2576814.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNENIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYNTSVFE
                     VHHILFEKGKIIIENLTNLENVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            complement(31272..32351)
                     /locus_tag="PC366_001281"
     CDS             complement(31272..32351)
                     /locus_tag="PC366_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HDF2576815.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLENDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSNVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLRFIKNI"
     gene            complement(32484..33830)
                     /gene="pepV"
                     /locus_tag="PC366_001282"
     CDS             complement(32484..33830)
                     /gene="pepV"
                     /locus_tag="PC366_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HDF2576816.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGQGEKMIGILGHVDVVPEGDLESWNYPPF
                     EAVLEDGKLYGRGTQDDKGPTISAIYAVKALMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELDKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDNEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTLLVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKATQIYALSIYELLKI"
     gene            complement(33899..35179)
                     /locus_tag="PC366_001283"
     CDS             complement(33899..35179)
                     /locus_tag="PC366_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine gamma-lyase family protein"
                     /protein_id="HDF2576817.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEEIKDKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(35306..35566)
                     /gene="hfq"
                     /locus_tag="PC366_001284"
     CDS             complement(35306..35566)
                     /gene="hfq"
                     /locus_tag="PC366_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HDF2576818.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR"
     gene            complement(35680..36615)
                     /gene="miaA"
                     /locus_tag="PC366_001285"
     CDS             complement(35680..36615)
                     /gene="miaA"
                     /locus_tag="PC366_001285"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HDF2576819.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDIDAEIISADSMQIYEYM
                     DIGSAKVTEEEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIHEINEKGKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQKQLAEKGIDYMHNKLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSSDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMIKNG
                     LVEEVKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTARWFDLDQYENIDELKNEIILYIKDSIK"
     gene            complement(36653..38620)
                     /gene="mutL"
                     /locus_tag="PC366_001286"
     CDS             complement(36653..38620)
                     /gene="mutL"
                     /locus_tag="PC366_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HDF2576820.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGIGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIKDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNNDLLESTPKNSNITKDKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASVEDDVKNINYLSEDSANDNIQEEFQVDGIKNEGNYYLGDSIK
                     DSEEEYLCSSKRKFSLYGYSVIGVVFNTYIILSKDDSMYLLDQHAAHERILYERYMEK
                     FYRQDINMQILLDPVVIEVSNVDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIF
                     GVPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLE
                     KCENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(38631..41474)
                     /gene="mutS"
                     /locus_tag="PC366_001287"
     CDS             complement(38631..41474)
                     /gene="mutS"
                     /locus_tag="PC366_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDF2576821.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIEKLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSEMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAESADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKALNDEVALMKQNDDKEKINQEDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(41637..42371)
                     /locus_tag="PC366_001288"
     CDS             complement(41637..42371)
                     /locus_tag="PC366_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2576822.1"
                     /translation="MLTQMNFYHNKKVKVSIENVSKTYKDIEVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLIL
                     KKEKKSKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRKLNEDNLENIIKLKKEIISLL"
     gene            complement(42340..43353)
                     /locus_tag="PC366_001289"
     CDS             complement(42340..43353)
                     /locus_tag="PC366_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2576823.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKDTSSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKDNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPQ"
     gene            complement(43375..44145)
                     /locus_tag="PC366_001290"
     CDS             complement(43375..44145)
                     /locus_tag="PC366_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2576824.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSMVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSMHAVVTIGEAILGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MDSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQAVKKVVIRHRLID"
     gene            complement(44120..44410)
                     /locus_tag="PC366_001291"
     CDS             complement(44120..44410)
                     /locus_tag="PC366_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HDF2576825.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(44541..44640)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     regulatory      45260..45349
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            45402..45578
                     /locus_tag="PC366_001292"
     CDS             45402..45578
                     /locus_tag="PC366_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576826.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(45693..46049)
                     /locus_tag="PC366_001293"
     CDS             complement(45693..46049)
                     /locus_tag="PC366_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2576827.1"
                     /translation="MDIDNNFEEFPNIEERQKDFNCSIGFTMTVIGSKWRAIILWHIL
                     KQEPIRYSQLKKDVVHISHKILSQELKYLERDGLIKRISYPTIPPKVEYLSTKRGKSL
                     ESILLELCNWGKQYMR"
BASE COUNT        15726 a         7233 c         5301 g        17945 t
ORIGIN      
        1 ttaaaatatc taagaaatta ttcaataaaa aaatactatt ttttaaaaat tatcattatt
       61 gataaagctc tactatttat attttttagt gtattcatgt ataataagta aaagcacaac
      121 ggtatatact gttgtgcttt tttgtaatta ataaacaata ttttggtcta taacaatgaa
      181 aaatggctac tttccataat tgatttcatc tgacataagc aaaaagggtg tccagctggg
      241 tcaatcataa ctctccagtc atcagtaaat tgctcctctg cgattgtagc tccacaatga
      301 atttcatatt gaactgcttc ttctaaatca ttaacagcga aatccatatg agccatttgc
      361 tgttgagatt caggtttttc tggccacaca ggcggtttat actcagaatt tcgttgaaat
      421 gttataccag gatatgttcc ctgatttgtt cctggagcac caacacatgc atattcttca
      481 ttataaaatg ctatttccca attgagtaac gctgcataaa attttgctaa ttcatgtggg
      541 tctttgcaat ccatcgtaaa tgagtacatt ttgattttca gttcatcatg cataacgtaa
      601 ttacctccaa gtataaattt cttcgtcttt tcatttttaa gctaaattca aacattaagt
      661 atgtaattta tttcaagtat ttttctatta tgccccaagc ctttgttttt tgcaatataa
      721 agaaaaaatt atatatttta atattttata attgttgaaa ttgtgtaata aattcaactg
      781 gatacatagt gcgttttgaa atttcttcta aagctaaacc ttgttttaaa agcctcttta
      841 tgacgctttc catactttct gaaatttcta taatattttt atcaaaatca taaaacctaa
      901 aagttctttg accccatggg tattctttta tataatgcaa aaattcaata tttcctattc
      961 tatttatctt actttcccat tgtttgatat cattaacctc aaaatacaac tgaaagttat
     1021 ttgattgttg atatattggt aaatcatatc caattatagc tttataatta ctttgtaatc
     1081 caaatccatt ttcaaatgat acatgttctc ctaaatctaa tgtaattttt tgctccataa
     1141 catcttcata aaactttttt gatttattta tgtctttgac aattagcaat actcctccaa
     1201 atttcatctt atcactatcc tttctttgtt ataagtatta taacttaaaa ttttgcaatt
     1261 tcactgtaaa aatcagacat attagctcgg tatttttgag gagttattcc acagacaatt
     1321 ttaaaatctt taataaaatg tggtatatca tagaatccta attcattaca tatatacatc
     1381 aatgaagttt tattattgtt tagaagtttt atagatttat taatacgtac caaacgagaa
     1441 aatgacttca tactcaaccc taggtactga ttaaagagtc tgtttaaatg cctagaacta
     1501 taaaatactt ttttagaaat ttcttgtgaa gatatgtttc cagagttttg aataatcaac
     1561 tgaattgcca aaataaactc atatgagtat tcaattttaa tattagaaat caataattct
     1621 tccaacttta aaatcaattt atctatagat aaagattcat taaatatttt tttaatttct
     1681 aaatctaatg aagtattaat tatagaaaat ggaacaactt tatcaataag ttcactttgc
     1741 tgtataccta taagcgggaa aaaaccagca ggttgaaatt ctataattag tataacatca
     1801 catctattag caatatttcc tactgttttt ggtttagtag ttggaccaaa taatagacta
     1861 tgtaaccctg tggcatcata aaaaaacacc aaagttacac ttccatgagg aataatcgtg
     1921 taattatcag aaattattgt ttgatttgga aacgatatag taaaattcga tatccaattt
     1981 tttaattgca tacaaggcaa gagataaaca aaattgtctt cacaaactat aagtgaccta
     2041 tttttattta taaaatgaat actttctttt tttaacatat attatatcct gtcctatcgt
     2101 gaatatttat taaagtaaga agaatccata ttatctctat atatcattaa ctgcttttaa
     2161 taatagagat agtatgaata ctcattagat atttaataaa caaataaatt aaaataatca
     2221 ataaaaaata tagtactttt atctgttatt ttaatattat agcacattta tagtatttaa
     2281 cttatatcca ctttacatat gtctaattta tatagttaaa aatgcttatc tcaaatacaa
     2341 taattagtcc ttatacaatt aaaccatctg aaactgtaat agtacgacta ctacttttgg
     2401 ctgcttctgg tgagtgagtt accataatta tagtttgtcc attgtctctg tttattttat
     2461 tcagtaaatc tattatttct atccctgttt tactatctaa atttccagta ggctcatcag
     2521 caaataaaat ctctggtttt ccaactaaag ctcgagctat agcaacacgt tgttgctgac
     2581 caccagataa ctctcgtggt gtatgtttac gtctatcagt taaaccaact atatctaaga
     2641 tttcatctaa ttgattttta taatctttta aatttttacc atctaataac aaaggaagca
     2701 ttatattttc ctccacattt aaatttggta ttaagttata aaattgaaat acgaatccta
     2761 tatttctacg acgtattatg ctcattttct catcattaaa atgtgatata tcagctccat
     2821 tcatatacac ttttccactc gttggagtat ctaaaccacc taaaatatat aaaagagtac
     2881 ttttaccaga accagattga cccatgatag aaacaaattc acctttcatt acttgtaaag
     2941 atacctcttt taacactcga gttgttgtat ttccaatttt atattctttg ataatatttt
     3001 ttgcttctac agctaaacta ttatgtgtaa ttttcatatt aacctccata attattcaaa
     3061 cttaatttct tctatcagtt tcattttctt cccttttata ataggcacta tcgaacctat
     3121 taaagttact ataattccca ataacccaac aataataaat gttttaaaat ctaaatctgg
     3181 tttcattgaa atttttggtc ctgcaactat aaagatagtt tgaatctcaa gtatagatat
     3241 cacaatacca ataacagctc caagtaaacc tgaagtaaac ccttcaatca atgtcacttt
     3301 tatattttgt ttatcactta gtcctataga tttatacata gctatagaac gttttttttg
     3361 aatataatta atcagtagat tattaataat acctactgta gcaagaagaa aaatgaaata
     3421 ggtcatctta ttcataggag acaaaaaact acttatagta tttaaagaat cattattaaa
     3481 ttcttcaact gtacgactcc aattatatgt atctccaaat aaatctctta tctgaatcat
     3541 aacaacatct ggattgactg ctgtatatac taaaaaacca taattagttt tatcaaaatc
     3601 attaactgca taatgtgatg gtataacagc ttctacatca tttgcacggg atttaaaact
     3661 acctactatt ttataagaaa aatcatactt atcattagat agagttattg tatctcctat
     3721 agataagcct acttttttta gagtatcttc attcaaaata acagaacgtt tatcattaaa
     3781 agcttctatt acttgttttt ttatctcaaa atttgtataa ttgattccaa acatagagtt
     3841 atatagtttt atattatctg taccctctag tcttgataat gttacaccat taccagaaat
     3901 ctcattattc ataacataaa gaggtaatat ttttttaatt ccatccatat gtctaacatt
     3961 ttcaataaac tcttcattca tctttccatc tgcaaaacct tgtaattctg cgtcacgaaa
     4021 cacatctgtt atataagttt tgacaaagtt accaacaaca cttattgcaa taactgcaga
     4081 aatacttata aatagtaaag tgatattctg tattatattt ttgttatttt tcatatttct
     4141 agcagctaat ttaccctcat tccctaaaat atttttataa acaaactcaa aaactataga
     4201 catgatatca gtaataagag gaatcaacac aatagtagct acaattaatc ctagtaatga
     4261 aaatccacca gctagataca atgtattttc aggggatatt cttggaagta aaatagataa
     4321 aataaacatt atacttccta taaaaagtat agaacgattt gaaacattct tttcttctac
     4381 tgttcctagt acaatatttt ttattggcaa atggctagct tttttaacag gtatatatgc
     4441 actaaatgaa gaaacgatta ttgctactat aacagatata atcactccaa tgggtgatat
     4501 tactactgga attgatattc cttgttcgag agaatttcct aacccatgaa gcattaaatt
     4561 taaaacaact acaccaatag gaatagcaat taatcctcct atacttccgt ataatatact
     4621 ttcaagcatc aatatacgag ttacagtttt ttcattggca ccaatacttc taaatgttcc
     4681 aataaaagga agacgttcta atgtaataac cttatagctg ctgtatatga taaatatact
     4741 aagggttaat gcaaaaaaac ttattaaaaa gaaaggcatt gtcttttgtc tagcatctga
     4801 aattatctta gtttcattta tagtatttga taccatatat ttttcagtgg aaagttcttc
     4861 ggataattta tttactagat tttctgtcat ttcttcttct gactctataa gaactcttgt
     4921 atatccactg cctttattta taatttttga tagagtctct ttgggtagca gtgcatttac
     4981 acctcttgta ttcctcaaaa atactgtatc ataagatgca atatcactaa cttgaaaagt
     5041 ataagacttt ccataaatct gtaaagtaat agaatcacct ttttttattt tatattttga
     5101 tgtaaagcga tttggaagaa taattttatc accagaaaaa tcagtaatac tatcgccatt
     5161 ttctaatcgt ggcttgttga ttttatttag ttgacttaag tctgctgata taagactaaa
     5221 ttcttcatag tatccccctt tattataaat agcagagctt tccaatacac caacctttga
     5281 ttttatagca tttaaatcag gtatgtcttc taaattggtt aatacatctg gatttttact
     5341 ttggacagat atagtcgctg taccatacat accttttgcc atttttcttt gtgcactttc
     5401 ataagataat ccaattgaga atgaaacaaa aagtaaaact gttgataaaa ctatggacag
     5461 taacataact gctgttctaa tttttcgttc tttaatattt gtgaaaatat actttaatat
     5521 aattttcaaa tttacacctt cttcctttat ctaagatatt tcagtataat atttttatac
     5581 tttaatccaa attgaatctc taatagactc ctccatactt ttatcattct atttataata
     5641 tttttaatca aatcacctcc ttaaataaaa aagattgata aactactata taaatataat
     5701 aatctatcaa ccttaatata ttttttattt gaccttaatt aaccttaatt aaataggaaa
     5761 ggtgatataa aatgagctac ctaatccagg tatactttca acagatatat tccctccatg
     5821 aacttcaata atttgcttcg ttattgctag tcctaaacca gttccttcta ttttttgttt
     5881 tgtattgctt cctctataat aacgattaaa caaatttgat gcttcttctc ttgacatccc
     5941 ttttccatta tcagatataa tgatttcaat tctttcattt aatgttatat gtacacaaac
     6001 tttagtattt ttatctccat atgtaaaagc attgacaata agattactaa aagctcgttt
     6061 taatagtgta caatcaaaat caaagttaat attatctata ttactcttaa attcaactat
     6121 atttgattca tattctggat aatttaaaat atcaatggat aattctttca agaatcttac
     6181 taaatcatat ttatttttat ttaaaggaat tattccattt tttaattgat aggttaattt
     6241 taaatcgttt ataagtgtat ttgtatattc tatattcttt aacatgattg aagcatattt
     6301 atatactttt tcaggtgaat aattagtact actatctgta agaagctctg catacccttt
     6361 tattggtgaa agtggagttt ttaaatcatg agttatattt gaaatccact cttctctcat
     6421 aatatcagtt ttattttgta tctcatcact tctatgaatt tcttcattta aaatatttaa
     6481 actattatat atatcagcaa aaacaccttt aatattaact ggaagatagc ttcgttttga
     6541 aatatcacta acagcagatg taatatttga tatgcacttt gttacccagt aaccataagc
     6601 aattccagaa atcaaaatta ttaaaaatat aatccctatg attgaaaata caattgactt
     6661 accacctaca aatttacttc catcaaaaaa catattcact ttagatatat ttaatggaaa
     6721 atatataata taaatatagt catttttatt atttttaatt gtattaaagt atacagttcc
     6781 attacttgaa ttattttggt tagctaatgt taataattca gaattagaat aataatcttt
     6841 atgctctttt ggttctaaaa acccataaac tctatttcca ctagaatcta aaatttgcaa
     6901 ccacaattga ttttctcgaa gcttttctaa tccagactgt tttacttgtg gcttattatc
     6961 tataaatatg atttgttcat taaagttttc tgtaaatttt ttcggccagt cactacgaat
     7021 aaattcccca tttggtttct gaatagtaat aagtgataag aaaataccta ttactgtcag
     7081 gattaagcaa ataaaaatca tgaaaaaaat aatgtatgaa tgaaatactg ttttataact
     7141 aggtttatgc atttaatcaa ctcttttctt aaacttttat tttagtttga ttgttgctta
     7201 tataaaatag ataataatta ttgatatgta aaaatttatt taaaaataca actatctaca
     7261 taaattatat ttatataatt atatgttatc aagctgtctg ttgtatttaa taaatccttt
     7321 tgataacata taaaagcaag ataatttttt ccattaaata ccttataatt atacacaaaa
     7381 tctctatata cgttaaacag tatagagaaa attttcatag aaccatcttt ataggggata
     7441 ctttataaaa gaataaaaaa attataatat ataaaaaact tcataggagt gtaacaacat
     7501 cagtaaagat atgaaaacac tatataaaaa ttcaaaaata ttaagaataa tgaaatactt
     7561 gaaattgctt atatcaagaa attttatata atataaactg gtcaaatatg ttataatatt
     7621 aaattgtgac aagttcatgg aggtgtttat atgaaaaaac aaaagtcgcc aattttactt
     7681 gaaatgcttg gactattttt gggttgtata tcaatgagta ttggtataaa tatgttttta
     7741 aaaccacata caattgctcc tggaggactt agtggtctat cattagtact aaacaaggtt
     7801 acaggacttc cagtatcagc tatcatgtta attataggtg tcccattagt aatacttgct
     7861 tttagaatta tgggtacaaa aaattcatta aaaactttat ttggaacagt tgtattttca
     7921 gctatagttc aattaacaga cccattatca aaactaagat ttactaatga cttattattg
     7981 tcttctattg caggaggaat cctagttggt ataggtttag gaataatgtt taaatcagat
     8041 gcttctactg gaggaacaga cttaattgca ctcatactta gtaagaaatt cccaggaata
     8101 aaagctacaa aattcatgtc atgcctagat ggaatggttg ttatatcttc tggtatagta
     8161 aatcgtagtt tagaaactgc tctttactct ggtatagcac tttgtgtatt aataaaaata
     8221 gcagatatga taatggaagg atttgaccat tcaaaagcat tttttattat ctctgatgag
     8281 cctgaaagtt taagacaagc tataactgaa gaacttgata gaggtcttac tattcttgat
     8341 ggtaaaggtg gatacactag agaaaataaa gaagttctat tagtcgtagt ttctaaaaaa
     8401 caagaacttt atctaaagag attagttaaa agaactgacc ctactgcatt tgttattgtt
     8461 acagatgtgc atgaggttct tggagaagga tttaaaaatt tagagaacta ataaaaatta
     8521 atattttaag tatatatact attttaatta aaatacgatt tattcaaaaa gagtgtctca
     8581 taaacttttt agttcatgag acactctttt ttgtataaaa tcaaatgcat tttcagtatt
     8641 ttaacaataa aaaacaggat tatctatatt ttgagtcaac tactttattg aaattttatt
     8701 tagaaaacaa tcattactaa ataaccagga tagatattaa atgattatat ctattgtttt
     8761 ttcaattcat attgataaca aggaacattt tttacagtat ttccagtatg aatttttttg
     8821 atatactttc ctgtacattt aaatcctaat aaatctaatg attttgtaga attttggttt
     8881 tcttcatagg ttattgcaat tattttattt aagtttagtt ctctaaatcc atactgtatt
     8941 actctttttg ttatctcagt agcaaaatca tgtccccaat agcttggatt tatacatata
     9001 cctatttctg cttctaatgc tttaggattt atattattaa accccatatt cccaataact
     9061 ttattgtctc ttttatatac tatagcaaag tggccaattt tccctttttt atagggattt
     9121 agaaaaaatg attttataaa ctttcttgta tcttctaaag atttatgctc actaaatggt
     9181 aaatgtttta ctactatttt atttttataa cagtcaaaaa aatcttcaac atcatctaat
     9241 gatgcaggtc ttagtataca acttctagtt tctaaggttt tcatttgagg atattcagaa
     9301 tcagacattt ctaatccccc tttatacatt aatctaaata tactgttcat atttaaaata
     9361 cgatattaat tatataaatg ttctcaaatt aaccttatct ttatttttaa taaaaactaa
     9421 ttactatatg aatctttcaa atttacgaat ttatctctat ttttatatta aattacttgt
     9481 gaaatatgta ttctaaatta tatgttatta gatatcatgc ttaaaaattc tttggttgct
     9541 aaggataaag atatatcttt taaatggcag taacctatat ttctcttagg tattggctct
     9601 tttatatcta atttaaacaa tttctcattt tccaaataat ctatgctaaa ttcttctata
     9661 acacaagaca ctccaagatt tatatacgca aattctaaaa gtaattcatg agaacccaat
     9721 tctatatccg ggtttagttt tatacctttt gataaaaaat attcatttac ataaagtctt
     9781 gaatttgctt tattttctag cattattaaa ggcaatgtgt ttaattcttc caatgatatt
     9841 ttcctacctt tgtattctat gtaatcattt gcacatacaa atatatcatg tatttcaata
     9901 cactcaacaa tatttagtgt atcatcttct attggcatgt ttataattgc tatatctata
     9961 ttcccatctt tgagtaaaga tataagttct ctactcgttc tatttattgt agatacatgt
    10021 atatgtggat acttcttatg aaaaatttct aaatatttta acaagaaaaa acgtgcagct
    10081 gtatctccta ctcctatttt cagagaaccg tattctaatt ttttaaattt atttattcta
    10141 tcttctcctg atgatatcaa ctttaatgca gtagtgacat gttcacttag aattttcccc
    10201 tctggagtta attttactcc cttattgttt ctataaaata ataaagtatc taattgttct
    10261 tctaattgct ttattgactg gcttacagct ggctgtgaca taaacaattc cttagcagca
    10321 agagaaaaac tcttattatt tacaactgca ttaaaaacct tataaagttc aagttttata
    10381 ttcatatata attactcctt atgtcaaata ttagtattat ttattttact tataattata
    10441 tttgaattat aatatacatg gtactaatat gacaatatta attctttagg aggattttag
    10501 ataatggata gattagttgg aactgtttca agaggggtta gagcacctat tataagacaa
    10561 ggagatgact tagttaaaat agttgttgat tctgttttaa atgcgtcaaa aagtgaaaac
    10621 tttgaagtta gggacaaaga tgtaattgcc gttacagaag ctgttgtagc tagagcacag
    10681 ggaaattatg ctcacgttga caatattgca aaagatgtaa aagataaatt tggagatgat
    10741 actgttgggg ttatattccc aattttaagt agaaatcgtt ttgctatatg tttaaaagga
    10801 attgcaaaag gatgtagaaa agtcgtatta atgttaagct acccttctga tgaagttgga
    10861 aatcacttaa taagtattga tgaacttgat gataagggaa taaatccttg gtcagatgtt
    10921 ttaacagaag aaaaatacag agaactattt ggatataaca agcatacatt tactggtgta
    10981 gattatgttg attattataa gaatttaatc aaggattgtg gtgcagaggt agaaatagta
    11041 tttgcaaaca atccaaaaac tattcttaac tatacaacaa gtattttaac ttgtgatata
    11101 catacaagac aaagaacaaa gagaatttta agacaaaatg gagctaaaaa agtatattca
    11161 cttgatgata taatgacagc aagtgtagat ggtagtggtt acaatgacca gtatggactt
    11221 ttaggttcaa acaaagctac agaagaaaca gtaaaattat tccctataaa ttgcgatgaa
    11281 gttgtaaaca aaatccaagg taatataaaa gaaataacag ggaaagatgt agaagtaatg
    11341 gtttatggag atggagcttt taaagaccct gtaggtaaaa tatgggaatt agctgaccca
    11401 gtagtatctc ctgcttatac aaaagggcta gagggaactc caaacgaagt aaaattaaaa
    11461 tacttagcag ataatgattt tgctgactta tctggtgatg agttaaaaga agcaatttca
    11521 aaatacatag ttgaaaaaga taataaatct gatgatttaa caggaaacat ggtttctcaa
    11581 ggtactactc caagaagatt aacagacctt ataggttctt tagcagattt aacatctgga
    11641 agtggagata agggtactcc tattatttac atacaaggat atttcgataa ctatacaaaa
    11701 tagtatgttt taataagatt taattttttt ggattatata tattaacatg aaaatttatt
    11761 aaaacctctt aatagatatg acttttcaag agttatatct attaagaggt ttatttaatg
    11821 ttcacagata agatatattt aaataattta aacaagattg tcataaagtt atataatctt
    11881 aaaaatttat ataactctaa ctcttattta tttctgaaat aatatcactc ttcaaaattt
    11941 gtcttactgg aataattaca gcaactatac taatagtgat atttaaaata atcataccta
    12001 tgtatagagg tgtatttatt ttaagaattg gatttatata taaatataca cgttttacca
    12061 taaaataaat cataaattgt ccaataacac ttccaattac cattataata cttgcataga
    12121 atccatataa aaaaccttct cttatcatca taagtaaaaa cttattatcc gtaataccca
    12181 tagctcttaa aattccaaac tcatgtcttc ttgaaaaaat taagtagctt actgtattga
    12241 ttatatggaa caaacttatt gcaagaagta caaatacaat accatatata aataagagtt
    12301 tttgatttaa gtaggtatta tttttttcaa tagcaatggt ataatctgtt acgatacatc
    12361 tttttacatc acttacaaca ctttttatgt tctcagacaa ttcctcactg ttactatctt
    12421 ctgtcttttt tatacttact gaattataat tttcgatatc aaagttattt ttcatttgcc
    12481 cattcgtcat aactatatcc ataccataat caccaatgaa atatatgtta tttgccatca
    12541 cacgttttac agtagcagca actacaaatt cttttgttgt ataatcattc ttattttctt
    12601 ctttaaattt aacaatttca cctgttggtt tcattgtctt tggcacttta acttttattg
    12661 tatctcctgg atttatatca actgcatcat acatcccagt tccatccata ggtagtctaa
    12721 ctataacctt attattttta accatatcat gggtattaat ctccccatct ataatataag
    12781 aatttaatcc ttctaacata ccattgttat aaccataaat atttgttttt aaaagatagc
    12841 caccttcatt ttgctttgta caaataccat caaaaaaagt ctttatcctg taatcttttt
    12901 caagaggttt aaagaaattt ttccaaaata gttgttcttc tttaatttgc atagctccaa
    12961 ataaatatct tactggatag acttttgata ttccctcaac attgtttaat cttgaaattt
    13021 tatcttttgg tatacctaca tcaaaatctg ttgtttgcat agttatttgg tagtcagaat
    13081 ttaaaccatc atcagctttc attgtaagtt cattattgtt tttagtaagc tgtatagagt
    13141 aactagaaca tagaaatata attccaccaa gtgataatga aaacaaaatt ccaataaaca
    13201 ttcccctttt ttgagtcatg tatttatgag ataatacttt tgtcatgtta gagtgtttta
    13261 cactttctaa tattctcttt ttcttattag taatcttaaa gtttttcata gattctatac
    13321 tagagtattt attcaactga tgtacaacac gtacagcaat taaaattaac aacaataaga
    13381 taaataaaaa gcctaaataa atagattttt cacttataaa aaatgctcct ggaacaatat
    13441 cactactcaa aaatatatgt ggaaattgtt catatattgt agacgctact ccaataccta
    13501 agaagcaacc tataggaaat ccaacaataa aaagtaaaaa taactctaaa aatagtagaa
    13561 ataaaagttg tttattatta gcgcctaata cttctaaaac cccatattgt gatattctct
    13621 gaagtattga aacatggaaa atactatata ctgctgctgc accaaacact ccaacaagca
    13681 atataattgc atttgtattt agttctaaat tttttaagaa ctcaaatata ttatattttt
    13741 ctatattctt tggtggtttt actccaaatt caactgaaag aggccagttt atataagttt
    13801 tttcttttga tatgttgaat tttttcataa atttataatt ttgcttttta atatttttat
    13861 tttcatcata ttttacataa actatataag aatccttttc tttaggctgc aaataatcgt
    13921 ttacaaatcc ctccatagca gtttctgggt ttgaaagact tgataaaata ccacataact
    13981 tatagatttt accatctaaa ttgatttctg ttccaatttc tttgtttaca tttaaattgt
    14041 ttagagaata tgtgtcaagt actatctctc catctttact aggaagagtt ccttttaata
    14101 attttctacc tgtcatgtct aaatatgaag aatcagcatt taaaaattct ataataaaag
    14161 gttcatctat ctgattttta ggttttgtaa cgccaagtct atctacaatg tattcctttg
    14221 attttttatt ttttttaatt ttattaagtt gttccttatc tactttatag aaataatgat
    14281 aatctccact atcttccctt atcttttcaa ttctactttt gtctgcacta tgaactaaag
    14341 aaccaattcc cgtcaataat gctactgata gtactatgct taaaactata gatatagatt
    14401 gttttttata atgctttata tattgaattg aaaattttac tagagacatc atagtacttc
    14461 accaccagta ttcaccacaa ctccatcttc aatatggata attgagtcgc atacttgtgc
    14521 tatattttca ttgtgtgtta ccataagtat cgtttgatgg aattttgcac tactttcttt
    14581 taataaacat accacttcca ttgtagtttt actatcgaga tttcctgttg gttcatctgc
    14641 taatataagt gcaggtttat ttgccaaagc tctagcaatt gctaccctct gttgttgacc
    14701 accagatagt tcgcttggaa attttaaacg cttatcccaa attcccaatg tcttcatcag
    14761 catttcaata tattcatggt ctatatggtt tcctttatct aatgtaacag gaagagctat
    14821 attatcataa gtgtttaata cgggcattaa actgtagttt tgaaatataa atcctatatt
    14881 tcttcttcta aatactgtca aatctttttt tcctatttta gatatgttct ttcctttaat
    14941 tattacatca cctgaggttg gattatctaa tccacctata atatttaaca atgtgctttt
    15001 tccagaacca gaagttccaa ctatagcagt aaatgtatct cgttcaattt ctatacttac
    15061 tccatttaag gcttttactt tagtctcacc ttttccatag tgtttcacta aattattcgt
    15121 cactaatata ctcatttaat ttctcctttc aatacagata tatgttctat aaaatattgt
    15181 aagtgacgat aattacactc atcctacaaa gttagtttaa actcttacaa ttctgtaaga
    15241 atatactaaa acaacatcca cttcctagtt tagattctac tataatgttt ccattttctt
    15301 tttctaaaat taatcttgta agatatagac caatccctgt gccattttgg ttttccacat
    15361 ttttacttct gtaaaatctt ttaaaaatat catttagttc tctactatca atacctattc
    15421 cttcatcttt aatagtaatc ttcgtatata gctccatttt tattacagaa atagtaatcg
    15481 tgctatctga tggtgagtat tttattgcat tttctaaaac atttacaatt gcttctatgg
    15541 tccacttttt attatgaact aactttatat ctgaaaatgg ttcgagattt atccttatat
    15601 ttttagcttc tgatttatta aagatagtac tgatgctttg aataagagta tctttaatta
    15661 gtagttcttc tacttcaaat tctataactc catcctctaa tttagtcatt ttaaataagg
    15721 attgtaacaa ccagtcaatc ttaaaagttt catttttcat cttttgtaaa aactccttct
    15781 tctgtaatgt ggaaatattt atattctcca gaagttcaca ataaatggtt atatttgaaa
    15841 gtggagtttt taattgatgt gacatatttg atattaaacc tttaatcgct tctttttctg
    15901 actttgactg ttctacctct atttctatca tatccttaat tttttttact tggtgagaaa
    15961 tttttgacgc tcttgtatcc ttcgtatctg gataagtaac ttctttacct tccaatattt
    16021 gatttaacat caaatttaat tcatcatatc ttctttgatt tattttagta gatactataa
    16081 atataacaac tgtacatatt ataaaggcta atataaacat attattctac ctcattccat
    16141 aaataaccca ttccataagc tgtttttata tattttggat tagatgggtc atcctctact
    16201 tttactctaa gtcttcttat atttacagat acaatattat catcaacata attttcttcg
    16261 ctgtcccaaa tatggtgtaa aatttgttcc tttaataata tctgaccttt attttcaatt
    16321 agataactta gaagcttata ttctacagag ctaagttcca aacatgcttt atttttatat
    16381 acttttagta acttttggtc caattttatt ccattggaat atattacttt attattcgat
    16441 ttttttctta ttgctacttt gactcttgcc tttaatacag ataaagaaaa tggttttgta
    16501 atataatcat caagccctat ttctaatcct tttacttcat caatttctga gtctcttgca
    16561 gtaagcatta taattggtat atctgacttt tcccttatta tttgacatac atcaaatcca
    16621 tctccatctg gaagattgca gtctaagatt ataaaatcta tatttttact attaaatata
    16681 tttaatcctt cttgttttgt ataagcctta aatacattaa atccatcatt ctcaaatgca
    16741 taaaaaagac cttcatttaa gtttatatca tcttcaataa ttaataagtt caattttact
    16801 ctcctttaga ttttttagat aaataattat tttcttgcat tatcatacta aaaatatttt
    16861 aattttattt atttcactaa aaagattgta tttaaatttg ttttcaaaat aaaaacatca
    16921 taatcaagca tatagttata tatttcccaa tttaattacg cttaaattga aaatataacg
    16981 ttattcttat ataattaaat tatacaacaa taaagttata ttttttaaat atatttttac
    17041 tagggggaat agaattgaaa agggttgatg agagaaatac tatgtttgca agagcaaatt
    17101 acaaaaaaga tagtactgct tataatgatt attataagaa aaatcctgac aaaaaagaaa
    17161 ttgatgatag tataagaaat agaccaaatt tatgtagtga aggaacaatg acttacaatg
    17221 agttaaactc tccaatggca agtagtgcat tcgatttttt atctgatatc aaatctttat
    17281 gcgaaggaaa agtttctgat actaaagtag atgtagatgc aaagtcaatg acaaaaaaaa
    17341 ttaagggtct tgcaaagcag tatggagctt ctgtagttgg tataactaaa ttaaaagact
    17401 atcatattta tacaaatagg ggtagacatg aagaaaatta cggtgaagaa attaatctaa
    17461 ctcataagta tgcaattgta tttggatgtg agatggataa agaaatgata aatagagctc
    17521 caatgatatg tgaagttata gaaacatcaa agtgctatgt ggatgcatct atcgtcggca
    17581 tgattttaag ttactatata agaaatttag gatatgatgc tagaaatcat atggatgcta
    17641 attatttagt aatgcctgtt tttatagctc gtgatgcagg tttaggagat ataggaagaa
    17701 atgctatact tacaaataaa gattatggct ctagacttag attaggtgtt gttactacag
    17761 atattcctct tttagaagat gaatatgttg attttggact agaagatttt tgtaaggtct
    17821 gtaaaaaatg ctcttttaac tgcccttctc attcgctttc taatgatatt aaaattggtg
    17881 atgatggaaa atataattgg gtaattgaac atgagacatg ctatattaaa tggagatatt
    17941 taggtacaga ttgtggtatg tgtatatctg cttgcccatt tagccaaaat ctcgaaacta
    18001 taaagaatac tacttcattt aagggtaata atgagcttat tcaaaaagct ttagatgagt
    18061 atacttcaaa atttggtaaa agaatattta tacctggaaa tccatcttgg ttgaaataat
    18121 tttatttaat aaagaatctg tactagaatt tatcatagga caggttcttt attaaatata
    18181 taaattttta aatacttttt ctcgtttata acaattcagc aatgttttta gtctataatt
    18241 gacattataa aatattaaac taaaaggagt aactgtatgg aaaaaatatt agtagtagaa
    18301 gatgattcta tattaaataa aactctatca tataacctaa ttgaagatgg atatataatt
    18361 acttcaaaat ttacagctaa atctgcacta aagtctattt ttgaatgtga atttgattta
    18421 ataattttgg atattaattt accagataaa agtgggtttg aattatgtaa tgaaataaag
    18481 gaaaattaca atataccaat aattttttta actgctaatg atatggaatg tgatatgatt
    18541 aaaggctatg aacttggagc tttggattat ataacaaaac catttaatat caatttattt
    18601 aaacagaaag ttaaagcttt tttaaatcat cttacaacaa aaacaaaaca agattactat
    18661 agggatggat atcttgaaat taacttttct gagttatctg ccaatataaa tggaaatcaa
    18721 attatattta caccattaga atatcgtact ttaaaactgc ttactgaaaa tcctaaaagt
    18781 attttaacaa ggaaagtact tttagaaaaa ctctgggata tagatgctaa ctttgtagat
    18841 gaacatactt taacatctgt tataagtagg attagaagca aaattgaaaa agacaatctt
    18901 aagtatatca aaacggtata tggtatggga tatatgtggt taggtgaaag aaatgaattt
    18961 taaaaaattt tcttttagtt ctatttattt aataattgct gttggtataa tttttacagc
    19021 tattttattt aatatttcaa tttatctaat aactgatgat ttaaaactaa ttgctctatt
    19081 attaatatat acaatagtac tttgtggatt tatagcatta ataatatttt tacttcataa
    19141 aaaaatagtt atattttgtt ctaaaatatg tcacacttta gatagtatga tgaatagtga
    19201 agacaatatt gaaattgaat tagaagaaga aactatttta tcacgtatca atcacagatt
    19261 aattagaatg tatgaagtta ttcaagaaaa tcgcaatagt attgctatag agaaagctga
    19321 tttacaagaa ctagtttctg atctatctca tcaaattaaa actcctattg caaatttaaa
    19381 aatgattaat actactctac taaatcaaac atttaaaaca gaaattcaaa aggatttttt
    19441 aatggatatg gaaaaccaat tagataaatt agatttttta atgcaatcta tggtaaaaac
    19501 ctccagacta gagacaggta taatcacact atctaaaaag aaaaattcaa tttatgaaac
    19561 aattgctaca gcacttagtg gaattttgtt tgatgctgaa aaaaagaata ttgaagttac
    19621 agttgattgt gacccaaatt tatatataat tcatgacaag aaatggactt ctgaagctat
    19681 ttttaatata ttagataatg ctgtaaaata cacaaattct aatggtaaga tacgtgtagc
    19741 tacagaatgt tgggttatgt atacaaaaat agatattatt gataatggaa aaggaatatc
    19801 agaaagtcat caagcagaaa tctttaaaag attttatcgt gaagaagatg tacatgacat
    19861 agaaggtatt ggaataggtc tatatctttc aagaaaaatt atatctcttc aaggtggcta
    19921 tattaaagtt acatcagata ttggaaaagg gtcgactttt tctatcttct tacctaataa
    19981 ataaattttt aaatatttta tttgtaatga ttctgcaaca ttttgatttt atactgtatt
    20041 tacaagatgt taaggaggta ttattatgag tattttacaa gtaattaatt taaagaaata
    20101 ttatggacaa agttcaaaca ttacaaaagc tcttgatggt gtaactctat ctattgaaaa
    20161 aggcgaattt atttctattg taggtacatc tggtagtggc aaatccacat tattaaatat
    20221 gatgggagga ttagataatc ctacatctgg aaaggttatt ataaagggta aggaattatc
    20281 tactatgact gatgaacagc ttacaatctt tagacgcaga aatataggtt ttatatttca
    20341 aaattataat cttgttcctt tacttaatgt atatgaaaat attatcttac caataggatt
    20401 ggatggagag accatagata aggattttat aaatgaaatt ataaatatgc tttctcttga
    20461 agaaaaatta tatgatatgc caagtaatct ttctggtggt caacagcaac gtgttgctat
    20521 agctagagca cttgtaacaa aaccagctat tatactagct gatgaaccca caggtagcct
    20581 tgatagtaga actagttcag atgtactgag tttacttaaa gtgacaagta aaaaattcaa
    20641 ccaaacaatt gtaatgatta cacacaataa tgaaattgca caactaactg atagaattat
    20701 tcgtattgaa gatggaaaaa ttgttaacta ggaggtgtag tatatgttta gaaataataa
    20761 tcgcacattt ataagaaaaa tagctttaaa tgatttaaaa attaataaac ttaaaacata
    20821 tctttcaggt atcattataa tgatttctac atgtttatta ttaacagtga ccttagtttc
    20881 atataatgct tctgtagatt tagttaatgc atctccatat catgctatat ataaatctgt
    20941 agatgaaaaa gcaaaaaata tactatataa agataaaaac cttagtggcg taggaaccta
    21001 caaattaatt ggaagtaata aaaagacaga ctgtattatg tcgattgttt atgcagatga
    21061 tacagcaatt aaacttatga attttcaacc attgaaaggc aaactaccta caaataaaaa
    21121 tgaaattgct atttcagaaa aatatttaca ggaatttggt ttagataaag atattggaga
    21181 tagcattaaa ttaaattatt atgatgatat tacgaataaa gaagttcaat gtgattttat
    21241 tattgttgga tttctagaaa attattatca agataatgcc aagcaatact atacagtcgt
    21301 ttcaaatgat tattttaaga atatagcttc tacaccttta caaaataaaa gtaatacttt
    21361 tgacgagtca agacctgata ctgtagatgt attagttaaa ctatcagaag aaaatacaga
    21421 gaaagattca gcttcaatta agacacagtt aaagaaaatt ggtttatctt taggtattaa
    21481 gaaatataat atatacttaa atgataacta tattgaatca aatttaattg atggtgagca
    21541 gattattaca gttttagtag ttggaatagt tgttcttttt tctagcgttt ttgttatata
    21601 tagtattttt tatatttcag ttgttaattc agttcagatg tatgctaagt tgaaatcgtt
    21661 aggtatgact tcttttcagt taaaaaagac tatttctcta caaggaaata ttttgtcaat
    21721 tatttttatt ccattagggg ctatagcttc ttgtataatt gcttacataa ttcaaccatt
    21781 agcatggcaa atgatagctg atttatttat aattttaatt ttatcactgg taatgttttt
    21841 aactgttaga atttctttat ttaaaccagc tagaattatt tctaaaatat ctgctattga
    21901 agccatgcaa tatacagaaa ctaaatttag aaaacaagca aaaaatttta gttatataaa
    21961 tataaaaaat ctagcattaa agaatatcga gtcaaataga aagaaaaatt tgattgcatt
    22021 aatatcgcta agcattagtg gagttttatt tatttcaatc gctaatcttg ctaattcaat
    22081 agatttcaaa aaacaactat ctcaacaatt tgtctataac gaagattata taattagcat
    22141 taagagtgat aacttatatg agcatattac agaaatccaa caaaataatc cactaacaga
    22201 ttctcttaag aatgaaatta aatctattca tggagtaaaa aaattaattg aatccaaatc
    22261 aattaaaagt aatattatag aaccttacat caaagataga gacgaaaaac aatttattac
    22321 tctaattaaa ggtattacgc ctgaactttc aaaatcactt gaagaatata ttgtcagtgg
    22381 aaaaatagac tatacacatt tagattcaga tagtttaatt ataaataaat atagaacaaa
    22441 atcttatgga ttaaatttaa aagttggaga tacagttaca tttaatatct ttagtggaaa
    22501 tgatattatt aaaaagaaaa tgaaaattat aggaatcatt gacaattcca atacaggagg
    22561 tatgtttttt gcttcagaca aaactttaga atctctaaca ccatataata caaatttaga
    22621 tttttctatt ttaatagata aaaagcattc taaagaagtt gaagaaaagt tgttaagtat
    22681 aattcagaaa aattcaaatt taatgcttta ttcatatgaa gatgattata gaatgattac
    22741 tagagcattt caatatataa ttatagcttc atacattttt gttggtttaa tttcttgctt
    22801 tggtatacta aatatgacca ataccctaat aaacagcgtt ttaattagaa aaaaagagtt
    22861 tgccttactt caagccgttg gaatgacaag aaagcaactg cgaaatatgc tttatagaga
    22921 aggtctaaac ataagtatca aagctatatg tacttcaagt atactaggtt attttggttc
    22981 aaatctactt tgcactttta taaaagatgt aattagatta gactttatta attttaaatt
    23041 ttctatattt actattttaa ttttttcatt cgtattaatt ggtatacaag ttttagtgac
    23101 tgaattactt ataagaaata tagaaaaaaa atcacttaca gaacgcttac gttctcagta
    23161 agaatgtata taaaaaataa ccatttttta tacaagtttt aacataattt tttaaaagct
    23221 aaaaggatag aaaattttga ctttacataa ttttctgtcc ctctacttgt ttttatttta
    23281 tacagataca cttccttata tctccaagca acatcaccag agacataaac aagcatattc
    23341 cttattttct aaatatgtca attgcatgac ttgtaactcc tactaaatct tcacgttcac
    23401 aagtagcaag gtgatatttt aaatataacg caaatgcatc atcatccata gagtctactg
    23461 cttcacgcat atacaaagcc aaaccatctg atgcgacata atgcagtcta gttacattaa
    23521 atgcagacat caaatcatca atgttttctt tacgtacaag ctcaaacaaa tcctttggtt
    23581 cagacttagc agcaaatgtc tgtggatcaa tcaaaccttt ttcaatatat tcagatacat
    23641 taatatttcc tctatggaac ccctcgtcaa tgagacagcc atcagatata acgtatgcag
    23701 caaaaaccac accaccaggt tttgttacac gaattgcctc atgtaaagct tgttgtttat
    23761 cttctttgtt ataaagatga tatagtggtc ctaacagtaa cgtaatatca tatttattat
    23821 ctgggaaaac agataaatcc atagcattac cctgagtaat gcttatattt tcatttgatt
    23881 gagtattttt atggaaaacc tctatattat gttcgactaa ttccactgcg tcaacatcat
    23941 atccctgacg tgccagtgtg tgagaataac gaccagttgc agcgccaatt tcaagcacac
    24001 aatcacctga ttttatgtac ttatcaatgt aatgcatagt agtgagaaat tccaccattc
    24061 catgttttaa tgcaagtcga ctatcttcat cataagtatt ataaaagtca attaagtatt
    24121 gttttgtttc cataatctca cctcttctat attagttaat aaacatcaaa tagacaaatt
    24181 ccaatctggt ttttcttgtc ttataaaagc tgttaatata tttttcaaca ttttttcagc
    24241 actatatcta tctaatgtta atttttttgt tgctgttaag acagctatgc catgagtata
    24301 aagaaataaa tctaaaaata ttacttttgc acattccaac tctattccaa tgctttccga
    24361 aaaaagtctt gccttttttt cattgtcaat ttctttataa aaatcattcg cctctttcat
    24421 catcaaatct aaatcattta taaataacaa cttaaataaa tacgtttctt cttgagcaaa
    24481 ttcaatgtat gaaagcggaa gcagtaaata agggcttaca cttttagaat tacgataatt
    24541 aacaacatac tgattataat attcatatgc aaaagcaaga aattcatttt ttaattcatt
    24601 catgttttcg taacaagtaa aaattggtcg agtggaacac tgtaatttac ttgcaatact
    24661 cctcgcattt acagcttcaa atcccacttc tcttgtaata tccaagactg tattcaaaat
    24721 catttctttt gttatcttta ctttaggtgg catatatgtt cacctctcca ttaaattttt
    24781 ataaaacaca tatgttatat aactatagta acatatcaag aaattatgtc aagaaaaagc
    24841 tttgcatttt tttgcaattc ctaaaactta taaataaaac atgagttgca attaatctat
    24901 taatagataa cagcaactca tattttcctt taaatactct tctttttgtc taatatttca
    24961 tatacacaat cttctattga attaatatct ttttcttttc tttttttaga atcaattaaa
    25021 atgaaataca gtataaaacc tacagcaagt ccccatgttc cgcctttagc agcaattaca
    25081 cctcccataa gtccaatcaa tcccttctca acacctgtat tacatagctc cattgatagc
    25141 tttgtacata aatatccttg aactaaaagt gttactgaca atgctaatgg tataagaggt
    25201 gtagcaatct gcgcaattgg ataaaaacag ataaaaattg ctgaaaccca tactaatgta
    25261 cccatgccac taaaaacaga ctgcatggct tcctttccaa ccttgtacct ttgagcaaca
    25321 cttcctgtaa gtgtcgcagc taatggaccg cacattggta tatatggaga aaagattgcc
    25381 ataaaaatat ttcttatccc acttataaca ttagacctat ttgaattgaa atctatatat
    25441 tcatcttttc tattttcact ttcagaaagt actaagtttt cacctgttat aaaatcacca
    25501 aaggcaatta tgtatatcat aaaagccatt ggtatccctt gtataaataa cattacactt
    25561 ggaaaaccta ttccaaaagg agatactgta tttatcagat ttttaaaatc tactatgtaa
    25621 actaaattgt caaaactaaa tctaggaatt tctatttctt tactaaatat acctactatt
    25681 aaactcacta aaatagctga tactacacca tattctccta aatgaaataa aaatttattc
    25741 ttaactttta gagtatcaaa tctttcagaa aacattacaa aacaagcaac caaaattcct
    25801 actgttatag atataggata agaatcaaat ctccctttag gattaaactc tgatattata
    25861 gtcgatatac cgacacccat tagtattcca cctttaatag aatttggtat cttactaact
    25921 aactttccag ctacaccagt tatacccatt aaaataaata ttattcctaa atctatttgt
    25981 aaagctgtta atgcttgtat tctttcaatg cccatgctga actttaacaa atatgcagtt
    26041 gtaagagtta tagaagctgt aatccagcca ggtacaactg ggtctcccat aaaaacatgc
    26101 aaacagtata atattgagtt aataatagcc atactccatg ccacttcata gggtaatccc
    26161 aaaatttgtg tactaaggcc aattgtgcct aaacttgtca tacttgatat tataccttga
    26221 atagcttctg gtttctcaaa tctgtaatgt ataaatggaa ttcttatctt aaacattcca
    26281 aattttatat gaggttgttc ccttctagcg agtctttcca taacttcact ccacctttca
    26341 ataactctta taagtttaca actttataat tgtttataaa ttgtcaatgt cattaaaatt
    26401 agtatataac atgcaaatta tataaacaat aaattaaatc tataaaattg atagattttg
    26461 tgcatatata gaaaaaccgc ttcattttta gttacttaaa tcacttaata ttagttattt
    26521 aaatcacttg ataaaagttt tttataaaat tcaatagttc tattccatga ttcaaactgt
    26581 ccttttgaat ttccttctac agttccacct gaagaaaaaa tccctccact catactcata
    26641 cataaagtct cctttagagg cataatatat ggaattggta acggatgacc catattattg
    26701 tatgttaata attctacgtt atatggataa ttattttctt caaagatttc taatgcctct
    26761 aaacaagctt cataactatt ccatatgtta tcttcttttc cagcaatcat aagtatatct
    26821 gctttggaat tttctatttt tattctagcc tcttttctat tctctgctct tttaagactt
    26881 ttcttataag tactattaaa tccaaatgga ataccttttg atatattttt tttctgttct
    26941 tcaaagaata tatcattgtc tactttgata tatggaaatg gctctccttt atatgaccat
    27001 gatgaagtat catttccact catcaatcca ttaagagctt ggaaacaata aatgtgaggt
    27061 tgtgatacta caaccttttt aatttgttca tatcttgaag caagtaaaaa ggccaattct
    27121 ccaccctttg atgtcccatg tacaaatatt tctttagtac tggtaatttc attttcacta
    27181 atccactcaa atactttttc aaaatattct aatggaacct cttctaattt atctggtaac
    27241 ccttctaaag caaagtatgc aactgttagt acattgaatc ctctagatgc aagtggagct
    27301 gctaaaaggt ctagagcgtc taaatttcca tcagaaccac ctagcattaa aattgtttta
    27361 ttattagaat tttgtttata aaataatttt cctataaact catcagatat gtattttgtg
    27421 gtaatatctt ctgatttaaa tattctcttt aattcaactt cttttctttc agtagaagtt
    27481 tcaaatatca tattcataat tattggttta tcaatagata tattttctgc aaaattttta
    27541 ccttcagttt tagatttttc cagcgaataa attaacccca tacaattatc agccttataa
    27601 gtaccttcta taggttcaac taaatctaaa tctacttctc ctttttcatt tgaacaaaac
    27661 actccataag atgaaaattc ttctcccttg caccatggaa attccatttt cacacttatt
    27721 ttaagtttag tatttggaat taagtctgaa accataatct taagtctttc atccacaaat
    27781 gattctacat tgtatacatt tactttcata atctatttct ccttataata attatttatg
    27841 ctttatatat aaaacaactt tatctaatac aacataaata aatttttaaa ttaagacacc
    27901 atattgacta tttcatttta tcaacatatt tcatttttgt caatatattg tcttttttag
    27961 taatttaaaa ttatgtagtc tatatgaaat ccagttgatt tttggctaat taaagatagg
    28021 aatgctatta ggtttaaaat atatctattc aaaataaaaa accactcatt ttaagaatgg
    28081 tttttaatat aaactatttg ttattaataa ggatattttt ttatttaaat ttatataatt
    28141 gaacatctaa tatttaatgt ttaataaaat tatgcatttg caaaagtata tatggcatta
    28201 actcttgcta catataaatt ctcatcacta catccaatat atctagcata tttttcaatc
    28261 ttttcttttg cattttcaac atcattttca tcgctctcca ttaactcatt tatataaata
    28321 tccattaatg acgctttata ttcttttata tcatagccta aaaattcagt caatctctca
    28381 atttccttac taaaatctcc atcttctttt accaaaaatt cgtatacatc ttccctatat
    28441 ggatttaaag ttattatttg ttttactact ttgcattcgt cagccttccc aataaaacca
    28501 tctttataat tattaaataa ggcattagat ttttttatag attcttcatc aatataagaa
    28561 tgtaccgcag ttatacgatt ttctataagg gcatctacaa cagcataatg aattttaaaa
    28621 caatcattgt ataaataatt gctcattttc tttattgtcg attctatttc taagaagcta
    28681 gcgtgcccat tttttttatt tttatttggt ataataaaag ttttattcaa gttattaaaa
    28741 agtctcttaa aatctaaata tttttcacaa taaacgcttt taaaggtatc gatatctata
    28801 gttataattc caaaacttac tatagtctca attcctttct taaaagactc ttctatatat
    28861 ttttctccta aacttaaacc tctatcagat atttgcttta gattttgaaa actatttaaa
    28921 caatctctct caaagttttt agatatttct aaagcatata atttaaagat tttccttatc
    28981 ttattataat tattttttgt atcatcaaat ctgataatag ctccatttac atcaaaagta
    29041 atcattgagt tttaacctcc ccattagttt catcaataaa ataaatttaa tataaacttt
    29101 ataatcataa tattaaactt atttatacta taattattaa tttgatgata aaagctattt
    29161 tccttctaaa taaaaaattt gtctaaagtt tctaaaaaat ttagacaaat cttaggttat
    29221 tattctttaa attattttta aattattcca aatacaccaa ataatattgg tataaatata
    29281 gctggtaaca aattagctac ttttatattc gttaatttaa gtacatttag accaagtcct
    29341 ataattaata aacttccagc tgctgtcatt tctgtgacta caggatcact taaaaatcca
    29401 tttaaaaatg atgctcccac acatataata ccttcataca aaaatacaga tattgcagaa
    29461 aacattacac ctatacctaa agaagcagta aatataattg aagctattcc atctataaca
    29521 gattttacaa ataaagtatc atgacttcct gtaagaccac tttctaatga accaactact
    29581 gccatggctc ctatacagaa taataaacta gatgatataa aaccctctgc tatagaatct
    29641 tttttatttc ctttagaaaa tttactttgt aaaaaagcac ccaacttatt tacccatttg
    29701 tcaatatcta ttaattctcc tatcagagca cctacagcta cggatattat tgtcactaat
    29761 gtgttttttc cttctagtgc tcctgatata ccaatgtaca atacacataa ggcaattcca
    29821 ttcattatag tatcacttac tctttgaggt aatcctcctt ttattataag acctactata
    29881 catccacctg caattgctag actatttgct attactccaa acattttttc tcccctcgat
    29941 tagctaattg aaatttatcc tattattaaa acctaagcat ctatactttg tattggatat
    30001 tttaaatatt ccaaaaattc ttcaaaacct tttctagata tatttacagt tttagtattt
    30061 atgttaggat gaaaatttaa gtaatcttct ttaattacat ctttatctat gtaaagctca
    30121 acttttcttt ctgtatcatt tattaatgaa aaaggattta cacttccagg aagaagttta
    30181 agtacattgt atagtctttc aggtgaagca aacgataatc tagaacttcc tatcttatct
    30241 ttaagtgagt ttaaatcaac ttgtttttct cctttaacta caataagata atacttattt
    30301 cctttggcat ttcttaaaaa taaattttta cattgacacc cctttgttat tccatctaaa
    30361 atgactaatt gctctgctgt atatacagct tcatgctcta ctacatcata ttcaacattt
    30421 aatttatcca aaatatcata tattttagtt tcattcatgc tagattcatt ttcatcttgt
    30481 tcttttttat tatttaaatc actcatactt ttctccttaa acacttcatc ataatatcat
    30541 tgtgaggtat tattctacta tagctattgc tcttactgga gctccatcag catcattata
    30601 cttaaatggt gctgctataa atagaaattt ttctggaaca ttttctaaat ttgtaagatt
    30661 ttctatgatt atttttcctt tttcaaataa aatatgatgc acttcaaata ctgatgtgtt
    30721 atatctatcc actgatagca tatctattcc tatgcctttt atattagtat tagctatata
    30781 gtttgcagct tcttttgtta atgtaggata acctacatag tactgctttt tatcccaaaa
    30841 ttttgaccaa cctgatttaa atattataaa atcactattt tttatttcat cttcatattt
    30901 ttttagatat tctaattcta tattctcatt tcccttttca agttccaata cataagcttt
    30961 cccaacaaaa ttttctatat ccaacttatc tagggtctca cctttagtat acatatgtct
    31021 tggtgaatcc atatgagttc cattgtgaga aaatacacta attaatgttt cttgataacc
    31081 attttcttca ataatagcta ctttcttgat atctggtcta ttaggctctg catatacagg
    31141 catgtcatta tgtgtcacat gagttaaatc aaaaaccttc atctttatat accccctatg
    31201 tttttatttt ctattatata cctaaattca ttttatttct atcagatttt attccattat
    31261 ataccatact actatatatt ttttataaac ctcaagggat ttaccgaaaa atcttggaaa
    31321 gaattatcag taaatataac atcttcaccc aaaaaacgtt tataccttcc ttcttctttc
    31381 tttaaagtaa ttctctgttt ttgtgaatga ttattaaaaa ccattatctt aagaggaggt
    31441 ttttttctat tagtctgcac tctttttaac atgtatttta tgtgcatatc agcttcagga
    31501 aatgaatatc cacaaaatat taaaaggtca gtatctctta aagttttttc tgtttcattc
    31561 caaacattac ttaaaaatat gtttgacata ttcttaaaat atgttggtgg cactataata
    31621 ggttctgtta actcaccaca ctctaaacat tttgtctctg aactattttc aataagcttc
    31681 atgacaccac cttcatgtgg tgtaagagtt acactattac aaatggggca ataaagccaa
    31741 ttcaatgacc catgtatctt atataatttg attaatggtt cttttggttt tctccaattt
    31801 aactcctctt taaaatttgt aaactccaca ccataatcaa gcataattgg caaatcattc
    31861 ttatctctta atccagtaac tgtattgtct atatgtatat cataatttgc actaataaaa
    31921 gtagtatcaa gaagcaaatc attttccaaa agattttcaa ctaaaagttt atgatattta
    31981 ttatctgttc taggtgtatt atgaattgct tcagccatta gcagtattaa atattgtctt
    32041 aaaaaacgta tactatcact tctgttattt agattttcta gtccaaaatt tctaaatgct
    32101 tcttttcttt gttctgctaa gtctaaaaga cctaaaactt cttcaaaggt aggaaaattt
    32161 gcattatcta tattatcttt tactatatca atattgaaca tctgtttaaa gaaaatatac
    32221 aattctctat tcattttggt attataattt gtgggattta gttttttaaa atattcgcta
    32281 aaaagttcat tttgaatagg tagattctct gctgctgaag ctcctgctcc taaaaatatt
    32341 gctattttca tatagttcct cctaatataa atattactcc tatttttata tccattaaat
    32401 atccatatca tttattttat gatacaacaa taaagctgtc ttttactaga aaaaatccta
    32461 ttacaagaca gccttatatt atattaaatc tttaataatt cgtaaataga aagagcatat
    32521 atttgagtag cttttataat atcctctact attaagtatt cattagcttg gtgttctgtt
    32581 tctggttttc ctggaaaaat agctccaaat gcaacacaat tatctaaagc tcttgcgtat
    32641 gttgctcctc cagatgaaag tggtgttcca tcaagaccag tttcttcttc atatactttt
    32701 ctaagtgtct taacaagaag agtatcttct ggaacataga ttgaatccaa gaaatcatat
    32761 tcttcataat ttaaattgta tttatctgtc attttcttta actcttttac aaaatcatcc
    32821 tttttgtatg ttactggaat ccttacatct attcctgcaa attctttttc gttatcaata
    32881 gttactctac ctatatttac tgttagttta cctgatacat catccttgca attaggaatt
    32941 atattgtttc cattagcatc ttcaccaata acttctgcta aaaacttaat tatattagaa
    33001 tctataccta tattattaag agctatacaa agtctagcca ctgcatttat accagtatca
    33061 cttgctgctg aatggacact ttttccaatt atacagattt tattaccttc aacagtatac
    33121 tcaaaattta atttatcaag ttcttttttt aatttatcag agtattttcc aatatagatt
    33181 gctttacctg gaactgcatt taaagccttt ccaactgaca actctatatc acttttgcta
    33241 tcacaagtca aatgaacttg taaaagacct ttctctgcat ttgttattgg gaatctagaa
    33301 tctggagtaa atccatagtt tggtatttct tcattatttt ctttatattt atttatacat
    33361 ctccaaagat tttcttcatc agccccaaaa atgaatctta tcctcttatt aaagtctaca
    33421 tttaaatcca taagagcttt cactgcataa attgctgata ttgtaggtcc tttatcatct
    33481 tgtgttcctc ttccatacaa tttaccatct tctaaaacag cttcaaatgg agggtaattc
    33541 cagctttcta aatcaccttc tggaaccaca tcaacgtgac caagtatacc tatcattttt
    33601 tcaccttgtc ctatttctgc atatccataa tatccatctt tgtatactgt cttaaatcct
    33661 aaagatttac ataagtctaa tatacctctt aaagctttat ctacattttc accaaatggg
    33721 caattttcag ttgcttcaga tataacacta ggtattttta cactttcttg tattgaagaa
    33781 atcatttcat cttgtagaga atttactttt tctttaattt gctctttcat attatcaccc
    33841 ttcaattttc atcataatat actaataaat attttgacct ttttaaaaaa aaatatgctt
    33901 attttttcag tttttttata aattcaatcg cttttaaagt ccccattttt gaatggtcaa
    33961 atgtaagtcc accttgaaaa taaacattat aaggaggtct tattggagca tctgcactta
    34021 attctataga agaaccttgt ataaatgctc ctgctgccat tatgacttca ctttcgtatc
    34081 caggcatgtc ccaaggaaca ggttttacat aagaatcgac tggtgcagct tcttgtatac
    34141 cttcacaaaa acttattact tcatcagcat tattaagtct aatacattga ataatatcac
    34201 ttcttaagtc atcatatttt ggtaatacat catatcctaa tttttcaaaa gctcttgagc
    34261 aaaagatagc tcccattaca gcctgagata ctatataagg cgccaagaaa aaaccctgaa
    34321 gtacatttct agttgttcca aaagtaagac cacattcttt tcctattcca ggagaagtca
    34381 ttctataaga tataagctca atcaaatctt ttctaccagc tatatatcca cctgtcaatg
    34441 caagcccacc accaggattt tttattaaag agccagccat aacatctgct ccaacatcag
    34501 taggctcttt ggtatctaaa aactcaccat aacaattatc aaccattact atagcttctg
    34561 gtttaacaga ctttattact tctatagctt cttttatatc actaattgaa agtgattttc
    34621 tccaagaata tccttttgac ctttgtatca taacgagttt agttctatca tttattttgt
    34681 ttttaattcc ttctaaatct aagtttccat cctctaaaaa atctacatca tcatatgtaa
    34741 caccatactc tttcaatgaa cctttttctt ctcttatgcc tataactccc tctaaagtat
    34801 catatggtct accagtaaca gataaaattt catctcctgg tctaactata ccttgtatac
    34861 ataaagtaag tgcatgtgta ccatttacaa ttattggtct tacaagagca tcttctgtat
    34921 taaatacttt agaataaatt tcctctattt tttcacgacc aatatcatta tatccatatc
    34981 ctgtagtcca gttaaagtgc atatcactta gtttagattc ttgcatagct tttaaaactt
    35041 tatattgatt atattctctt atttctttta tttcttcaaa cttatctttt atttcttcca
    35101 ttatttcttg cgatagttta aaagtatcat catctattcc atagtagtct tttaataatt
    35161 cttttgtctc attaagcatt ttatcacctg tctctttatt attttattta aacatgtaaa
    35221 ggagactatt ttactaaaac aaataaatta tagtttataa gttagtataa gtctcctctc
    35281 aatcatctta aattaaatta attatctatc tgttgttatt attattgttg ttttggtttt
    35341 gatttgttag attaatatac tttccaggtt gtatagttga tacagcatgt ttataaatca
    35401 tgttttgttg tctattatcc ccttctatta atattatata actatcaaac ccctttacaa
    35461 gccctttaac ttgcactcca ttaactaaat atatagtaac aggtatcctt tctttccttg
    35521 cattatttaa aaacaaatct tgtaaattta aaactgtatt tttcattaga tttgtaccct
    35581 cccaagatta aattgaactt ctaaaatatt cctaccttat attctatata agttatgaca
    35641 aattttcaat attaagttgt atacttaaaa atttatatat tattttatag aatctttaat
    35701 atataagatt atttcatttt ttaattcgtc tatattttca tattggtcta aatcaaacca
    35761 tcttgctgtt ttatatcttt taaaccatgt tatctgacgt tttgcatacc ttctagaatc
    35821 tcttttaatt atttcaatag cttcttcgta tgtatattct ccatccagat acttcaatat
    35881 ctctttataa cctatacctt gcattgatat catatctttt ttaaatccca tacttaaaag
    35941 tttttttacc tcttcaacca atccattttt aatcataata tcaactctca tatttattct
    36001 ttgatacaaa tgttctctat ctctatttag aactattatt attggttgat attcttcatt
    36061 aaattttaaa tcacttgaaa aatcattcat tttcttacca cttagacaaa cttcaagagc
    36121 tcttatgacc cttttagtat tgtttttatg gattctatta gcagattctt catcaagttc
    36181 ttttaactta ttatgcatgt aatctattcc cttttcagca agctgttttt gaagttcttc
    36241 tcttaattca ttattggcat cagattgtgc aaaatccata ttatatatta aagagtttaa
    36301 ataaagtcct gtgcctccag ttactaaaac acattttccc ttttcattta tttcatgtat
    36361 atattttttt gctctttgtt gaaactctga aactgaaaat ggatagtcag gcttaacttc
    36421 atctataagg taatgcttca ctccttgcat ttcttcctct gtaacttttg cacttccaat
    36481 atccatatat tcatatattt gcatagaatc agctgaaatt atctctgcat ctatatcttt
    36541 tgctaatttt attgacaaat ctgtttttcc aacagcagtt ggacctgtaa gtattataag
    36601 tggtattttt ttcataacat tcctttccat atattttaaa tatccaaata ttttacataa
    36661 ttcttttaaa cattttttct atttctgtct tagatatttc gaccattata ggtcttccat
    36721 gagggcatgt aaatggattc tcacactttt ctagctgttc caataaactt tttatttcaa
    36781 tatcgtatat tttatcattt gcttttatag cagacctaca tgccatagat gcaaatctct
    36841 ctccttttaa atcataatta cttgtaattt cttctatatt atcaattatt tgaagtataa
    36901 atttctcagt ttcaggtact ccaaatatag taggaacaca tcttaccatt atatgattat
    36961 tgccaaaaat ttctagttca aaaccaaatt tcataaataa ctccaagtta ttttcaattt
    37021 gaagcatatc tacatttgat acttcaataa ccactgggtc taaaagtatt tgcatattga
    37081 tatcttgtct atagaacttc tccatatatc tttcatatag tattctttca tgtgcagcat
    37141 gttggtccaa caaatacata gaatcgtctt tgctcaaaat tatataagta ttaaatacaa
    37201 ctccaattac agaatatcca tataaggaaa acttgcgttt tgaactacac aagtattctt
    37261 cttcactgtc cttaatacta tctcctaagt aataatttcc ttcattttta attccatcaa
    37321 cttgaaactc ttcttgtata ttatcatttg cactatcttc acttagataa ttaatgtttt
    37381 ttacatcatc ttctacactt gcatttagga cttcacttac tgattgaaat tcatttattg
    37441 gtttttcact tgataaagtc acaacttcaa tgacttcatc cttatcttta gtaatattac
    37501 tatttttagg agtagattct aataaatcat tatttcttaa tttataatct gtactttttt
    37561 ctctactgtt aatagcgatt ctaggttgtg tttttttatc actataagta gcatattttc
    37621 caataagatt tgagtgtatt aatttaacct ttaaaaaatc tctaagttct atatacactt
    37681 cttgttcttt ttcaaattta atttcaagtt tattggggtg tatatttaca tctatacatg
    37741 atgggtctac ttctatattt aagaagcaca ctgcatgttt acctattgga attatagact
    37801 tataactttc tgttattgca tctatgatta ttttactttt tacaaatctt ttatttatat
    37861 agatatgttg taagttttta tttgaacggt atatattgtt attacctata tatccattca
    37921 ttttaaagtg attgcactta aactctacat ctattatatt ttccgttatt tcttttccat
    37981 atatacttct aatagtgttt acaagttttc catcccctgg agtatttaac atctgtttat
    38041 tgttatttgt atatttaaat tgaatgtttg gattacctat tgcaagttta tttatcaaat
    38101 cacttatgtt tatagtttct gcatgagtag attttaaaaa tttctgtctt gctggtgtat
    38161 taaagaaaat atcttttata atgatggtag ttccattagt agaacctatt ggttcttttg
    38221 atattatttt tccgccttca acatatattt tagttcctat tatttcatct ttagttttag
    38281 tcgtcatttc taattttgat acagctgaaa tagatgccaa tgcttctcct ctaaaaccaa
    38341 gagagtataa atcatacaaa tcatcaattt ttttaatttt actagtagca tgtctcaaaa
    38401 atgatttttc aacttcactt gaaggtattc ctattccatt atctgtaatc ttaattagac
    38461 tttttcctcc atcaattata tctatggaaa ttttatttgc acctgcatca atggagtttt
    38521 caataagttc ttttactaca gaagaaggtc tttctacaac ttcacctgct gctatcttat
    38581 ttatagtcaa atcatctagg atgttaatta tatttttcat ttttacacct ctaagatttt
    38641 atttcttttg cttttctttg aagattataa agagagttta tagcatctaa tggagtcata
    38701 tttaaaatat ccagatttaa aatttcttct gatagtatat ctctatttac actatcaaaa
    38761 gagatttgag ttaaggctac ttcttttaca gaatcttctt gattaatttt ctctttatca
    38821 tcattttgct tcattaaagc aacttcatca tttaatgctt taaatttaga atttaattta
    38881 tcataatcct tttttatatg tttgtagtct tttactataa gttcatgttc tatttttaga
    38941 gattcatatt tattcttaaa attactttga tttaccttaa ctaattcttc gtccaaatta
    39001 ctattaatta tattattgtt ttctttatct ccatttattg caacactgtt gtaaacatga
    39061 tttttttcca agtctttaag tatatatttt gctctttcta tgacttcgtc tggtaattta
    39121 gctaatttag caacatatat tccataactc ttgtctgctc cctgaggaat tatttttctt
    39181 aaaaatatta ttccttcccc atcttctttg actgctattg aataattttt aacctcttta
    39241 aactcttctt ctaaatcagt aagttcatga taatgtgttg caaataatgt cttacatcta
    39301 atattttttt gaatatattc cactattgac catgctaaac ttatcccatc ataggtacta
    39361 gttccacgac ctatttcatc taatataact aaacttctct ctgttgcatt ttttaatata
    39421 agggatactt cattcatctc taccataaaa gtagattgac cttgagataa atcgtcacta
    39481 gctccaactc ttgtaaatat tctatctaat attggaatat cagcagactc tgctggtaca
    39541 aatgagccta tatgtgccat aagagctatt atagcagttt gtctcatata tgttgattta
    39601 cctgacatat taggaccagt tattatgtta ataatgtttt ctccacgatt taaataagta
    39661 tcatttggaa cgaaattctc ctctcctact atattttcga caacaggatg tctaccattt
    39721 cttatatcaa gtttattatt ttcatttatt gctggtttta catagttatt tatatgtgca
    39781 actgttgcaa gggacacaaa aacatctata ttagctatag tcttagccac tttttgtatt
    39841 ctatctatgt ttttatatat tgtatctctt atctctacaa atatctcgta ttctaaagat
    39901 ttaatctttt cctctgcatg tagtatcttt tcttctattt cctttaattc tggagttata
    39961 tatctttctg cattactaag tgtttgcttt cttatatatg tctcatctag ctttgcctgt
    40021 ttaaagttgg cttttgttat ttctatataa tatccaaaaa ctttattaaa tcctattttt
    40081 aatgatttaa ctcctgtttt ttctctttcc ctgttttcta tttcctttac aagaaaggct
    40141 ccattcttag aaatctctct tagttcctta agttcatcac taaaatctga tttaattatg
    40201 tttccatctt ttatggttat cgtaggttct tctagaatag cttcatctat taaattgtat
    40261 atatcatcta atttatccat ttctgaaaca tactctttta ggatttttgc atttgataaa
    40321 tttatagtat cttttaaatt aggtaacttt tctatcgaat tttttaagtg aattaactct
    40381 tttggtgtta ctctctcaaa tgctatcttt ccacatattc tttctatatc gtatatattt
    40441 ttaagtatat catttaggtc ttctcttaat ataaagtcat cttttatttc ttctattaca
    40501 tctaatctat tttcaatttt agatttattt atcaaaggtt cttctacata ttttcttaaa
    40561 agtctacctc ccattgctgt agaagtttta tcaagtacat gtaataatga accttttttc
    40621 ttattccctc ttatagtttg agtaagttct aaattagttc tagtaaacat atctaaaacc
    40681 atatattctg atgaattgta tatatttata ttattaatgt tagatgttat ttgtttttga
    40741 gtattgtata tataattcag aagaattgat aagcttgact ttattagacc tttatcatca
    40801 aactttagtt tttgtagata aacatctgga aaatattctt ttaatatatt tatatccaaa
    40861 tagttatcac taaaactttc atttatgtat atattactta cagtagctat atctctaagc
    40921 ttttctataa agtctaaatc atttataatt atttcagttg gatggatttt tgcaatttct
    40981 tcaattacct tatcttcatt taaacatgtt gcattagttt ctcctgtact tatatcaaca
    41041 taagttagac ctatattagt accatcctta tacaaagata ataaataatt attcttttta
    41101 ttttcaagta aatttccatc taaaactgta ccaggagtga tgactcttat aacctctctt
    41161 ctaacaattc cttttgctgt agatgggtct tccatttgtt cacctattgc tactttatat
    41221 ccattttcaa ctaattttga tatatatgaa ttggctgagt ggaaaggaac accacacata
    41281 ggagcacgtt cttctaaacc acaagctttt cctgtcaatg ctatttcaag agcttttgaa
    41341 gctactaatg catcttcaaa aaacatttca taaaaatctc caagtctaaa aaacagtata
    41401 cagtctttat atctattttt tacttcaaga tactgtttca tcataggagt taatttattc
    41461 atatctattt gcattatcaa acctccttct tttctaatta aatattatat catagtagat
    41521 gattattatt aacacaatat ataaaatttt gacatataac taaaaacaat ccaaaatgta
    41581 tactcacatt ttggattgct aagtttaatg cttattaaat aaaaatatat atatttttac
    41641 aataaagata ttatttcttt tttaagttta atgatatttt caaggttatc ttcatttaac
    41701 tttctactat ctataacaaa ttctttcttt actattgatg gtttttttga aataacataa
    41761 attctgtttg atagcattat agcttcgtca atatcatgag ttataagaag tattgttgaa
    41821 tttacttttt tcttaacatc taaaagccat ttttgcatgg atgttttagt taatgaatca
    41881 agtgccccaa aaggctcatc taaaagcatt atgtcattag aatttataaa agttctcaag
    41941 aagttagctc tctgtctcat tcctccagaa agttctgaag gatatttatc ttcatatccg
    42001 cttaatccaa acacctcaaa ataaggtttt accattgacc tagctttact ctttttttct
    42061 ttttttaaaa ttagtggtag tgacacatta tctattatag ttttatatgg caagagtaaa
    42121 tctttttgat acatataact atatttacca tttatattca ctttgccact atcataatct
    42181 gtaagtttag ttataatatt aaaaatagta ctttttccac atccacttgg ccctaatata
    42241 gaaacaaact caccttcata aacatcaata cttatatctt ttaaaacttc aatatcttta
    42301 taagtttttg atacattttc tatagatact tttacttttt tattgtggta aaaattcatt
    42361 tgtgtaagca tcacttgcct tcatatcctt atctattaat ttatattctt ttaagaatga
    42421 tgtatagttg ttccatacac tatctttcat ttctccccat cgtggtgcat catctttgta
    42481 cttgcttgct aaatattctt gactctttaa agctagtttt tcatctactt caggtgcatg
    42541 ttttactaaa atttttgctg attcttctgg attttttatt gcatattcat aaccttttgt
    42601 tgtagctttt aagaattttt tagcaagctc tggattatct ttaagcacag tttcattaga
    42661 aattataagt ggtgtataat aatccaatct ctcatctaaa tcttttactg gtataaagtt
    42721 taagtcatat ccaattaaat cagctttaac tgcatcccaa ccttcaaata tccatgcaaa
    42781 atctacagtt ttcatagctg caaagaaatc atcttgacca gtattaacta tctttaactt
    42841 attaaaatca gctccatttt tcttcataac tgctttaaaa acagcttctt ctgatggaga
    42901 gccccaacca ccataagttt ttccttcaaa atctttagct gttgttatat tcttttcttt
    42961 tggtgatgca aacccagaag tattatgttg tataacagtt gctacagctt ttattggaag
    43021 tggatcttca ctagtctttg cataagtaac ttgttcttga tagcttatac caaagtcagc
    43081 ttttcctgtt gctactaaag tttctgctcc actttcaggt ggttgtacta tttcaacatc
    43141 caaaccttct tctttatagt aacccttatc aagtgctaca aataatccag tatgatttgt
    43201 atttggtgtc caatcaagca ccatagttac ttttttagaa gaagtatctt tatcattgtt
    43261 tttgtcttta ttgttatttg aagaacatcc agttattgtt gccaatgtaa aaacacttac
    43321 taaacctaat attcctaact ttttaaaatt cataattgcc tccctcaaat acctttaatc
    43381 aattaatcta tgtcttataa caactttttt tacagcctgt acaattccta caaacattaa
    43441 actaaatata actactaata tagtagatgc aaatacttta tcaagtgcat atgcactttt
    43501 tgacctaagc atataaacac caagtccttt cgttccacct agccattctg caacagttgc
    43561 tgccattaca gcatacgttg cagatatttt aagtccagaa aaaaatttat ccattgccat
    43621 aggaaattta aggtgaatga atgtattaac tttatttgag tccatagtct taaataaatt
    43681 taaataatct ttatcaatat tctcaatgcc atctacaaaa cttattaata taggaaaaaa
    43741 acaagtaagc attaccatca atacttttgg cattgttcca aatccaaacc atatcataaa
    43801 aagtggtgct ataattattg taggtatcat ctgtgtaacc aacataatag gataaagaca
    43861 tttttttatt attgatacaa aatccatcaa tattccaatt accaatgata ttataattgc
    43921 gactataaaa ccaagtattg cttctcctat agtaaccaca gcatgcatgg ataaattttg
    43981 ataatcttta aaaaacacat taattatatc tactggtgtg ggtagtatat actgaggaac
    44041 ttctaaaact cctaccatag attgccaaag aataagtata aacaaaaatg ttgctattgg
    44101 atatatacta tctttgactt tatctatgat ttctaagttt ttcatctata gtcagacctc
    44161 cagctttttc atctactcta gctactgtta tgactctttc acatccaaga ttaaaaggga
    44221 ttttatgtac cttttttaat aattcaaaaa cttcatcaaa atcaccttca acagtagtgc
    44281 tcattgctcc tatttcacat ttaagaccac ttttttcaat ttcagcaata caagcatcta
    44341 ctactttata catttcttct tcacctttgt aaggtcttag tggcattact gctatgtctg
    44401 cgattaccat ttaaatcact cctttaaaaa taattaatac ctactaggta tattttgttt
    44461 tttattaaaa aattttatta ctaaaaagat attatattta aataaaagaa aagtcttatc
    44521 caaaatagga taagacttat ttttatctta actggtctcc ctacactggc attatccaaa
    44581 caggttcaaa gggtcgagat aaaatctcct ctcagcacat tagctccccg aaatatatta
    44641 tatcttttct acttgattat actacactta tcatatttta acaaattttt tatttatatt
    44701 agatatttta tccgttcaaa aatatctaat atacattgta cattattaca ccaaataaat
    44761 tatcttaaaa tggtaattta tcaacatctt ccaaaactag attaactgaa ttttctagtt
    44821 tttattttgc tatttcaagc atatttggat gtatatcaat tccatacaaa tattgttcta
    44881 aatttctgtt ttcactaatc taatttgcaa tcgttacaga ttacagatta gaaatagctt
    44941 ttagactcta cttatcttta tctacaaaaa atccttcaat aaattcagta ataatattca
    45001 gtaatctaaa aataaacctc tatctggatt tttaagatac aagcctttta ggaagtatct
    45061 tttgtgataa tataaaaatt actcgtcatt atcatcaaaa tcctcagcaa ccaacatttt
    45121 agataagaat caaactctat aatataatta ttttatccaa tttatttttg agaaataaaa
    45181 tattttttta atttttaaat tttttaatat gcaccttgaa aaaagaaacg ttttcctata
    45241 ttatggtaat agtagaataa aactaaatag gcaaaactag agaaatttag tgacgcaaag
    45301 ctatagggac taagacttat gaaatgagtt atgtcagcca gttgccaaag agatattttc
    45361 tttttgtttt tatgaatgtt ttttaggggg atatatgata tatgtttatg gataaaatgg
    45421 atagatgtac acatatacta actgcatata tatgcagttc acgcgattac tgcaatttta
    45481 tagatacaca attaaatgat tttatactag aatatggaga gaatgtggta gaatcttgtt
    45541 tgcatcaagt gatggtattg gtaagcagat ataattaaag aaattttatt ttctagaaaa
    45601 ccctttttag ttttatctac gttttataat tcattaaaga actaatcaaa ataagcttca
    45661 ttatatattt ttcatgaagt aaacagttga gtttatctca tatactgttt accccaatta
    45721 cataattcta ataatataga ttccaatgat ttaccacgtt tagtagacaa atattcaact
    45781 tttggaggaa tagtcggata agaaattctc ttaataagtc catctctttc aagatacttt
    45841 aattcttgtg acagtatctt atgacttata tgaacaacat ctttttttaa ttgactgtaa
    45901 cgtattggct cttgttttaa aatatgccat aaaataattg ccctccattt acttcctatc
    45961 acagtcatgg taaaaccaat tgaacaatta aaatcttttt gtctttcttc aatatttgga
    46021 aattcttcaa aattattatc tatatccatc tcaatcctct ctttcaaaat agtaagtatc
    46081 taactaaaaa gtgcattctt gtttagcgta ctaattcgta atataatctt gattaaaaaa
    46141 tagctacgca cactcgtgac tttagtcatg agttagtagc taaaatagtc aacatatagg
    46201 gaaac
//
LOCUS       DAMJWO010000022        46154 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.023, whole genome shotgun sequence.
ACCESSION   DAMJWO010000022 DAMJWO010000000
VERSION     DAMJWO010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46154
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.023"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            127..1008
                     /locus_tag="PC366_001294"
     CDS             127..1008
                     /locus_tag="PC366_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HDF2576828.1"
                     /translation="MKKRLIIMILSVVLVLSSILTIFAYSNIKYNNNKLIYSNMIDKK
                     TQNSVKEILKENKINEKDIDTFIKAVNNYNKLQVKILQNNINISKSGYSSINAKQVPY
                     NLEKLQDNWVKKFPDYMDVNCRITAFRLFKDFINSNKKFTGDSIDLNVDLDTIMNNKD
                     AKFSTKDVEKFINFFSAIPAKDTDDTIKIAEQIKNEWKKRKISFKNNKNISIINGFLR
                     YPETKNVFIGHTGICIKTKNGILFLEKYGVTSPYQVTKFKNKKGVKNYMFNRLKMSEG
                     EIELPDPIIMENDKLMK"
     gene            complement(1321..2100)
                     /gene="hisJ"
                     /locus_tag="PC366_001295"
     CDS             complement(1321..2100)
                     /gene="hisJ"
                     /locus_tag="PC366_001295"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HDF2576829.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDVGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKENL
                     NKYGKELEDSLLSVHIIKIDDDYYCVDYSVEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNTILEDLIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLELVKKYDIPLVLGSDSHCAEEINKYDII"
     gene            complement(2640..2990)
                     /locus_tag="PC366_001296"
     CDS             complement(2640..2990)
                     /locus_tag="PC366_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HDF2576830.1"
                     /translation="MIFDKEIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            complement(3006..3422)
                     /locus_tag="PC366_001297"
     CDS             complement(3006..3422)
                     /locus_tag="PC366_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HDF2576831.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            complement(3441..3632)
                     /locus_tag="PC366_001298"
     CDS             complement(3441..3632)
                     /locus_tag="PC366_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HDF2576832.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            complement(3783..4598)
                     /locus_tag="PC366_001299"
     CDS             complement(3783..4598)
                     /locus_tag="PC366_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HDF2576833.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLVKELYEKYKNEEYNKKR"
     gene            complement(4645..5583)
                     /locus_tag="PC366_001300"
     CDS             complement(4645..5583)
                     /locus_tag="PC366_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2576834.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVIWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGKIDMPISLSAKLENDEQIKKFFSVGVDKIGIAIDASNKELYEKIKGNNYDEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYIYLKENDVTISLFAFTPVRGTKMEKIN
                     QPSIESYRRVQLMSYMINKGYPKEYFKFKNGYLNSIKLDNDILKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            complement(5580..6452)
                     /locus_tag="PC366_001301"
     CDS             complement(5580..6452)
                     /locus_tag="PC366_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2576835.1"
                     /translation="MNKNLSEKMKIAFDIKLKNFGNKIEFAYPNQTLALSTTSNQCSL
                     KCAHCNGHYLNNMVPIEEYEEKVQSRNITSFLLSGGCSYEGDVPINTHINTIKNLKEK
                     GYRLNAHLGLMDKDSIVELCKYLDIVSFDLVFDDETIREVYKMKKSKEDYIEVYNTIQ
                     EHTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIVLIPTKGTEYENVEPPELE
                     GVADILCEARINLPDTEINLGCMRPRGVYRKELDQLSIMCGVNRIVLPSRSAKNKAIE
                     MNMTINECKECCVL"
     gene            complement(6477..8405)
                     /locus_tag="PC366_001302"
     CDS             complement(6477..8405)
                     /locus_tag="PC366_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4445 domain-containing protein"
                     /protein_id="HDF2576836.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNSL
                     GYNEIDFRLDILRKMPTVFRKSDFKVTITYVQKQKKLTIINIEQGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKETLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            complement(8517..8894)
                     /gene="gcvH"
                     /locus_tag="PC366_001303"
     CDS             complement(8517..8894)
                     /gene="gcvH"
                     /locus_tag="PC366_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HDF2576837.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            complement(8981..11107)
                     /gene="cdhC"
                     /locus_tag="PC366_001304"
     CDS             complement(8981..11107)
                     /gene="cdhC"
                     /locus_tag="PC366_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CO dehydrogenase/CO-methylating acetyl-CoA
                     synthase complex subunit beta"
                     /protein_id="HDF2576838.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            complement(11164..11970)
                     /locus_tag="PC366_001305"
     CDS             complement(11164..11970)
                     /locus_tag="PC366_001305"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HDF2576839.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            complement(12020..13387)
                     /locus_tag="PC366_001306"
     CDS             complement(12020..13387)
                     /locus_tag="PC366_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HDF2576840.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDAKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRTALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            complement(13418..14362)
                     /locus_tag="PC366_001307"
     CDS             complement(13418..14362)
                     /locus_tag="PC366_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HDF2576841.1"
                     /translation="MAFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NSPKIGIQISDVYPESWTDSYKELYKDVANCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYAHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            complement(14382..15152)
                     /locus_tag="PC366_001308"
     CDS             complement(14382..15152)
                     /locus_tag="PC366_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2576842.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            complement(15208..16593)
                     /gene="lpdA"
                     /locus_tag="PC366_001309"
     CDS             complement(15208..16593)
                     /gene="lpdA"
                     /locus_tag="PC366_001309"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDF2576843.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVIEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTVKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            complement(16637..17518)
                     /locus_tag="PC366_001310"
     CDS             complement(16637..17518)
                     /locus_tag="PC366_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HDF2576844.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMQKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            complement(17554..18228)
                     /locus_tag="PC366_001311"
     CDS             complement(17554..18228)
                     /locus_tag="PC366_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HDF2576845.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKILGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNSENDCAWIKIYERLEAIGQLDNLAEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            complement(18265..19137)
                     /locus_tag="PC366_001312"
     CDS             complement(18265..19137)
                     /locus_tag="PC366_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/5,10-methylene-tetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HDF2576846.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLVKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQEEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSGVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLDKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            complement(19229..19861)
                     /locus_tag="PC366_001313"
     CDS             complement(19229..19861)
                     /locus_tag="PC366_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HDF2576847.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVNKVKIEVDKLVEDGVKICDEVYAKVEKALGK"
     gene            complement(19966..21642)
                     /locus_tag="PC366_001314"
     CDS             complement(19966..21642)
                     /locus_tag="PC366_001314"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HDF2576848.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNNENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKELGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFRFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLEKLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            complement(21891..22670)
                     /locus_tag="PC366_001315"
     CDS             complement(21891..22670)
                     /locus_tag="PC366_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2576849.1"
                     /translation="MKIAITGKGGVGKTTFSSMLSRMFAEDGYRVVAVDADPDANLAL
                     ALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKVDDIPENFCKEYNGVR
                     LLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAGIEHLGRGTAQGVDA
                     FIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEEFIIQNLEDGESLGF
                     IYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
     gene            complement(22980..24899)
                     /gene="cooS"
                     /locus_tag="PC366_001316"
     CDS             complement(22980..24899)
                     /gene="cooS"
                     /locus_tag="PC366_001316"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HDF2576850.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKAGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMESDAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            complement(25506..26417)
                     /locus_tag="PC366_001317"
     CDS             complement(25506..26417)
                     /locus_tag="PC366_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HDF2576851.1"
                     /translation="MIKKLDDILEQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKAKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGENVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            complement(26533..26655)
                     /locus_tag="PC366_001318"
                     /pseudo
     CDS             complement(26533..26655)
                     /locus_tag="PC366_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
     gene            complement(26738..27880)
                     /locus_tag="PC366_001319"
     CDS             complement(26738..27880)
                     /locus_tag="PC366_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDF2576852.1"
                     /translation="MDFKIEKYLLKKAEELAFITIKHGGEFKLKSYKVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     SYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEKVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALRLGLDAD
                     LVAEVQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMGEIEQAKMYLEKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELGINK"
     gene            complement(27898..29652)
                     /locus_tag="PC366_001320"
     CDS             complement(27898..29652)
                     /locus_tag="PC366_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HDF2576853.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVNMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYEAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMKINDVNGLVYRQGNEIIVNKPMELLQDLDE
                     IPSPYENLNPKEYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLDRIKSDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKQSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREVENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            29788..29994
                     /locus_tag="PC366_001321"
     CDS             29788..29994
                     /locus_tag="PC366_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576854.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            complement(29999..30922)
                     /locus_tag="PC366_001322"
     CDS             complement(29999..30922)
                     /locus_tag="PC366_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576855.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLTIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVIYFKKE
                     ELLFDYLLGSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKSEDYDEESILLNVLNVLYDVYMEDRTVENEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKSIDPRSLIRLEEGNTIIDPIFNQ
                     ITVMSKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(31176..32876)
                     /locus_tag="PC366_001323"
     CDS             complement(31176..32876)
                     /locus_tag="PC366_001323"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HDF2576856.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFNK
                     LENGDEEAQELWQWFRNESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKN
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLKLLGMHAPERM
                     "
     gene            complement(33287..33700)
                     /locus_tag="PC366_001324"
     CDS             complement(33287..33700)
                     /locus_tag="PC366_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HDF2576857.1"
                     /translation="MILVSACLIGINCKYSGDNNENEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGIKIKSEKDL"
     gene            complement(33768..36146)
                     /locus_tag="PC366_001325"
     CDS             complement(33768..36146)
                     /locus_tag="PC366_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDF2576858.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKSEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSEISAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTADSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKPGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIEKLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRNLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTRKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            36463..37914
                     /locus_tag="PC366_001326"
     CDS             36463..37914
                     /locus_tag="PC366_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HDF2576859.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLVTVNEEDGMNGADALDPSL
                     IKGQYILNMDSEEEGYLLVSCAGGKTCVVSLPVEYKEVKGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLNVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKGSKLEKICSETYEKLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANVWDYVIEILKSMNQY"
     gene            complement(38118..40631)
                     /locus_tag="PC366_001327"
     CDS             complement(38118..40631)
                     /locus_tag="PC366_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF2576860.1"
                     /translation="MEDCVVNLKKLLLLIIVITSIFTSCIFSFGINAIGNDNRTIRVA
                     YPIQKGLTEIDEQGNYFGYTYEYLLEIAQYTGWNYEFVQVPGEINESITKLMKMLENG
                     EIDIMGGMLYNEPMQKIYNYAGNSYGVANTVLQALYENTDIDNIMSSQDVKKIRIAVI
                     ENSDTRLKELDEYCKMNLMSPELVYCKTSDEQLEVLKSGKADVLLNVSMNPIEGVRTV
                     AKFSSKPFYFITPKGSTDLTQKLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDE
                     ETNYIKDTEKLKVGVLLNKPPFQNADKDTGELRGISIDLLNHICDKTGLEFELVPVKS
                     QEDLEDMAKKHEIDIVAGMIYDYEYSREHNIAMSRPFLSTQYTMMINNKLNENSLNGK
                     RIALAKGIDYYGQFEENIVWYDNLEECIEAVNKGYADYTYGEGYSMQYYMNQPKYKNV
                     RLVPQTYEAKSICFGIIKKDKQELLNIFNKAIISISSEKMQSIVYQNTTYRQDFSLLY
                     IMQQNPIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFE
                     YDYKQDKLIISMPEKGIETYYGLDKSDKESENGNIENERDKIRREYNKKFFDVIKSQE
                     NGTTEMYSIMLDDTFHWIRITSKIIYNDRKIPMYVIGKIANIDSEKEEKNRLLDKVQR
                     DSLTNIYNAAYIRKLTTQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLVGDKVLIDV
                     AKVLDESFAKDDIVGRLGGDEFSVYINDIINKEELINKCNDVYNHIHLIKLPNGESLS
                     ISMGVVITKRGQEYDELYQIADNALYDSKRQGRNRFKIV"
     gene            complement(40854..41675)
                     /locus_tag="PC366_001328"
     CDS             complement(40854..41675)
                     /locus_tag="PC366_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2576861.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVIEYNRESFELEPEKLLNFIKFRRSIRQYKDIEVEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIQGLYNLALDTDDNDPVRSIYKNT
                     FKKMYKRYKENGNDSLFYDAPLLMIVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEMR"
     gene            complement(42194..42670)
                     /locus_tag="PC366_001329"
     CDS             complement(42194..42670)
                     /locus_tag="PC366_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HDF2576862.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVGNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYDNGKLKDYNVSFLD"
     gene            complement(42704..43282)
                     /locus_tag="PC366_001330"
     CDS             complement(42704..43282)
                     /locus_tag="PC366_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDF2576863.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRELAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGDEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            complement(43386..46004)
                     /locus_tag="PC366_001331"
     CDS             complement(43386..46004)
                     /locus_tag="PC366_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDF2576864.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELNVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIETGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MNRVQATFQQDKEFIKTNIRAKVSIKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDEERIKIKD
                     RKFKKNRLKYQPNRVNKQKKLDTVPKIRVKVKNLEQLEAVLNYNVDLIYYEDINTLSK
                     ALQMASSISIDSSISIDSSISIDSSISMDLDTSSSLGIPKELMGSNTNNIDTLSNTSK
                     IDTLNKNHYNTAVTDKKLIYSAPRIVRNKEYKQFEILDNIKGINKVQIGNWGSMEYFK
                     KKDLNIDCYLNAFNSESINHFKEEGASTVCLSQELNLNEIKQTLKYTDVEIEAVIYGY
                     APMMVTEYCPMGVVVRDCKKDKRVAKCKESSYALRDFTDASYRITQDIFCRSTIYNSK
                     VTCMLDNLYELEEIGIDVFRIDFTVEDSEMVKKVIEAHIEVLSNNYKLGKKATDLYKK
                     LDEIGTVAGHYYKGVE"
BASE COUNT        14061 a         8907 c         5116 g        18070 t
ORIGIN      
        1 aaaagtttta aataaagtta tattttttac aacagttttg taattaaaaa catattgaag
       61 gtaaatttaa aggtactata tactataaat atgtcgacac aataaattta aaaaggagaa
      121 ctaaatatga aaaaaagatt aataataatg atattgtctg ttgtcttagt actatcaagt
      181 atacttacga tatttgcata ttcaaatatt aaatataata ataataaatt gatatattct
      241 aatatgatag ataaaaaaac tcaaaatagt gtaaaggaaa tcctaaaaga aaataaaatt
      301 aatgaaaaag acatagatac atttattaaa gcagtcaaca attataataa attgcaagtt
      361 aaaatacttc aaaataatat aaatatatct aaatctggat attcttcaat caatgcaaaa
      421 caagttccat ataacctaga aaaattgcaa gataattggg tgaaaaaatt ccctgattat
      481 atggatgtaa attgtagaat aactgctttt agacttttta aagattttat aaattcaaat
      541 aagaaattta ctggagactc tattgatttg aatgtcgact tagacactat aatgaataat
      601 aaagatgcta aatttagcac caaagatgta gaaaaattta tcaacttctt ttctgcaata
      661 ccagctaaag atacagatga tacaatcaaa attgcagaac aaataaaaaa tgaatggaaa
      721 aaaagaaaaa tatcttttaa aaataataaa aatatatcta ttataaatgg atttcttcgt
      781 tatccagaaa ctaaaaacgt atttataggt catacaggca tatgtattaa aactaaaaat
      841 ggcattctat ttttagaaaa atatggtgtt acatcacctt atcaagttac taaatttaaa
      901 aataaaaaag gtgtaaaaaa ttatatgttt aatagattga agatgtcaga aggtgaaatt
      961 gaattgcctg accctataat aatggaaaac gataaactta tgaaataata actttaaacg
     1021 caaaatagta tttataatta ctaagtcaat ataatagaga aggtctatag atttgtgtaa
     1081 atacaatctt atctacaatc ttatataaga atgtttatat aaataagata gattaattct
     1141 aagtcctatt attctattga attttattat tattttactt agattctatt gttattttac
     1201 ttagaactta ttgttatttt atttaagttc tattactatt ttcaatcata taaatttaca
     1261 aaagactgta cataaattta ttttatacaa acttatctac agtcttttgt gtgaatatat
     1321 ctaaataata tcgtatttat ttatttcctc tgcacagtga gaatcagaac ctaaaactaa
     1381 tggaatatcg tattttttta ccaactctaa taagtatcca tctatataag gctctttgca
     1441 atactctttt ctatttccag aaacattata atcaagttca taaccttttt ctttaattaa
     1501 ctttattaag tcttcaagaa ttgtatttcc tttataatcg tatggaaata cctgattaaa
     1561 ctttctaact aaatttaaat gacctattct ttttggttta tgtataccta aatctgaatt
     1621 tacagctttt atcaatgttt cataatactt attataaaca gcttcaatac ttcctaattt
     1681 gtcgattaaa ttttgaaact cctctacact gtaatctaca caataataat catcatcaat
     1741 tttaattata tgtactgata aaagagagtc ttctaattcc tttccatatt tatttaaatt
     1801 ctcctttatc ccttcttcgt atccttctat aaaatccact tccgacccaa catttatctt
     1861 gattttaccc tcatactttt ctttcaactt cttgacatca ttaaaatact ttggtaaatc
     1921 ttcaatactc atacaactat cattttcagg agcagggtct ctaaatccat ttgcatacgg
     1981 aaaatgttct gtaaatgtca tttctgttat tccaacatcc attgctcttt gtacatattt
     2041 ttcaaaatca tccttacttc catgaggaca ataaggtgaa tgtatatgac catctttcat
     2101 aaataattca ctcctttttt aaagaaaaaa tctaatataa atgcataaat tttttaactt
     2161 caaaataata tttttaatca tgctaatttt tattatatct aatattagag taattttaaa
     2221 ctgcctttta agtatcttat ctttagtact attttcaact taacattaat attatttttt
     2281 aacttaacat taatactatc tttaaatagt aatactcaat atataattaa tcaaataact
     2341 caaattgttt gatgaagctt ttgcagtatt taaagaatat ataattattt aacattaaat
     2401 aatccaatct tgtaataaaa tttactcatt aaagtatatt acagaaaata tctcaaaata
     2461 aactttttag ttcatgatat actctttttt gcatgaaatt agatatattt ttatcatttc
     2521 aacaatgaaa gggaggctta catccatctt gagataaccc cttagataaa atttttaata
     2581 attaaacatc ataaaatata aaaatcgctt atatcaaacg tataagcgat taattatatt
     2641 tacatatgtt ttttagcctc taacaacatt ttattagctt cttccatata ctctatagcc
     2701 ttttcaatac tctttgctgt ttcttctttt ccaatagctc tagccttttc aacccactct
     2761 ctaaatcctt cttcatgagt ttcattgtga tttatccaat gtactaaaag tatttttaaa
     2821 gttttttcat ccttagactc tgatgattcc tcatgactat gttcatggtc gtggtcgtga
     2881 gcatggtcat gtggatgttc atgacatata tctccatgag tatgttcgtg gcagtggtca
     2941 tggtcatgat gtccatgatg atatcttaca atctctttat caaaaatcat tagttattcc
     3001 ccctgttatt ttatattaaa ctcttttttt ataaggttta cagaatcttt tacaagtagt
     3061 gctaatggtt taccttctaa tccaactaac tccacatttt ctggcataat aggtaaaagt
     3121 atcttaagtg cctcactgtc tgcaatagct tcacttatat tacaagtaac ttctcccatc
     3181 atagaattag gtattattac agaaataggt gcaactatta tatttgcttt tttagctgat
     3241 actactatag cattttcccc tgtagctcct ttattagcat gagctttcat catagaacta
     3301 gttgctatag aattagtccc tagtgcataa atttctacat atgtaggtaa ctcttctctc
     3361 aaagaagaaa ctatctgggc tccaatacct ccacccattc catctatcac tgctattatc
     3421 atatgaaatt cccctattaa ttaattttct tgtattatta tcttatggtc catcaatctt
     3481 atttctttaa ttatcccatc tattatcttt tgctctccta ataaatccgt taaataaatc
     3541 tttccatcac aagggtctat attaaccaca ttttccataa ccttttctaa ctcattatta
     3601 cttttacaaa tgaaagctga tgattcacac atataaatct cctcctaata tgatttttat
     3661 taaaaatcaa aaaaagattc ccttaggtat ttcaatactc caaagaaacc ttcatgattt
     3721 cagtttttgt atattattat accttaagta tatcacttta atttatgtaa agtcaattaa
     3781 agttaacgct ttttattata ctcttcattc ttgtattttt catatagttc tttaactaat
     3841 tgcttctcat aatcagtcaa atcgccctcc acaaactcaa cattaaattg ttcagctaat
     3901 ccctttacta tgtttttctg tagaatatct atgtctattt ttctgccaat ttcattttct
     3961 attccacttg cttttttagc tgtaaatttc atagctcttt ctttcaattc tggtgtctta
     4021 gtttttatta atttaaacaa tttttctaca tcaaaatcca gtattattga accatgttgt
     4081 aataaaacac catcttttct gctttgagca cttccaatta ccttcttatt attaatagta
     4141 acttcatatg atgcatgtgc attaaaacat gcagctgata aattttccct acttattctc
     4201 tcgcctctat ttaaattatc tgtttctata ccacttagat tcaatccttt aactagacct
     4261 tcacttatat atctataaga taggttgatg ctcttatcga ttaaaggatt atcttctcct
     4321 ataattatac tataagttag ctcattatca tgtaatacag ctcttccacc tgtaattctt
     4381 ctagtatagt ctatattcat acatctacac ttatctaaat ctatctcatc ttccaatttc
     4441 tgaaaatatc ctatactcaa acaagctggt tcccatgtat aaaatctaag agttggctta
     4501 ttatgtcctt tcttatatgc agtaaatata gcttcgtcaa ttgccatatt cattgctcct
     4561 tcatatgatt tattatgtat aactctccac tgattcatga ttattacgcc cccattttta
     4621 gtataaatat atcctagaaa tcctctatag atttatttct cttattgcta aatctatctc
     4681 actttgattt aaaggtcttg aatagttgta tatagtactt ccgggtcttt cattatagta
     4741 tggtctatta caatccttac aacctcttat ttcaaaagga tagcctttgt ttatgtcttt
     4801 taaaatatca ttgtcaagct ttatactatt taagtatcca tttttaaact taaaatactc
     4861 ttttggataa cctttattta tcatataaga cattaactgt acccttctat aactttctat
     4921 gcttggttga tttatctttt ccattttagt tcctctaact ggagtaaatg caaataaact
     4981 aatcgttaca tcattttcct ttaaataaat atataaattg tatatatctt catgactttc
     5041 acccatacca actattatat gtgtacttat tttattggga tatgattttg acatttcagt
     5101 tataaatttt aacttttcat catagttatt tccttttatt ttttcatata gttctttatt
     5161 tgatgcatct attgctattc ctattttatc aactcctact gaaaaaaact tctttatctg
     5221 ttcatcattt tctaattttg cagatagtga aattggcatg tctatcttac cacttatata
     5281 gtttataaag tctaaaacag agttatgtgc ttcttcactt gccattgatt gaatacatat
     5341 tctctttata ttttttcctt tataagcttt taaagcatct aatatttctt cttttgaaaa
     5401 ctctggccaa attactcttg ataatttatc ttttctagta ctactttcta ttgattgaga
     5461 acaaaaactg catttattta tacatttttc tccaatcatt atatatgctg tggtaggagg
     5521 tatatcgctt tttttgttta atatcccaag ctctattgct gtcccaactg atagtctaat
     5581 cataaaacgc aacactcctt acactcattt attgtcatat tcatttctat agccttattc
     5641 tttgcagacc ttgatggtaa tactattcta ttgactccac acattataga taattggtct
     5701 agctcttttc tatacactcc tcttggtctc atacaaccta gattaatttc agtatctggt
     5761 aaattaattc tagcttcaca taaaatatct gctacccctt ctaactcagg aggttctaca
     5821 ttttcatact cagtcccttt tgttggaata aggactataa atgtaagctt attaggagga
     5881 tttttctgta ggtattctat aatttcatat tcacccttta tttgtcctcc ttttaaacca
     5941 atacatatat gtggtgctac ttctgtatgt tcttgtattg tattataaac ttcaatataa
     6001 tcttctttac tctttttcat cttataaact tctcttattg tctcatcatc aaacactaaa
     6061 tcaaaagaaa ctatatctaa atacttacac aactctacaa tgctatcttt atccataaga
     6121 cctaaatgag cattcaatct atatcctttc tcttttaagt ttttaatggt attaatatga
     6181 gtatttatag ggacatctcc ctcataacta caaccgccac tcaatagaaa gctagttata
     6241 ttccttgatt gtactttttc ctcatattct tctattggca ccatattgtt taagtagtga
     6301 ccgttgcaat gggcacattt caaactacat tgattgcttg tagtactaag agctagtgtc
     6361 tggttaggat aagcaaactc tattttattt ccaaaattct ttaatttaat atcaaatgct
     6421 attttcattt tttcagatag attcttattc atagtttatt ccttcttaag tacattttac
     6481 tcttctagta atttctttgc tgttgggaac tgctctatat tcgtatgtgg taagaaacat
     6541 gcagaaataa attcatccat ataacttgga tatacactaa gttcaacata agttatttga
     6601 ttacctattt cttcaagttt attttttgca tctttactta tgagagctaa gtaagaacca
     6661 acaagtgaac tattccctat ataagtaaat ttttctctat caatgtcagg aagtaaccct
     6721 ataattattg agttttctat gtctaggttg tttcctatac cacctgctat ataaacccta
     6781 tctaatatac taaaatccat acctaaacta tctacaagag tgtatgcacc tgaatatata
     6841 gctcctttag ctctgatgaa attatctata tcaacttcat tgactactat atcattttct
     6901 aaatcaaatt cttctttaaa tgctaataca tactctccta tctcatgctc attaaatcta
     6961 actctcttat tatctaaatc cctgtatatt ttacctcttc tatctattac acctttagta
     7021 atcatttgac agattaaatc aattatacca gaaccacata taccaactgg tgcacattca
     7081 tcaataatct ttaatgttgg ctctaaagtt tctttatcaa taattacttt ctctattgct
     7141 cctgctgatg ccctcattcc acagcttatc cctccacctt caaaagcagg tcctgctgaa
     7201 catgcacagc tcatcatata atctttattt ccaaatacaa tctctccatt agttcctaaa
     7261 tctataaata aaacattttc ttcacttgac catatccctg ctgataatac acctgctgtt
     7321 atatctcctc ctacataact tgcaacagat ggagctaagt acacatatgc actgtcattt
     7381 acaaaaagac caacattttc acccataagt tttggagatt ttaaaaatgg tggtatgtaa
     7441 ggttcttgtc ttaagaagtc tgtatacaca cccaagaata aacttgtcat agttgtattc
     7501 ccggcagcca ctaatgtaac tacatcttcc ttatctattc catttctttc atatattgtt
     7561 tttaatagtg gatttatagt ttcctcaact atagctttat gaagtgtctc taatccattt
     7621 ttcttagttg aatatataat tctatttata acatctgctc catattttat ctgtgcattt
     7681 ccagaagatg ctttatctac tacctctttt gaatataggt ctactaaaca aacaactact
     7741 gaagttgtac caatatctat tgcaactccg tataaggaat tttctttatt accttgttct
     7801 atatttatga ttgtaagttt cttttgtttt tgaacatatg ttattgtaac cttaaaatca
     7861 ctctttctaa atacagttgg catttttcta agtatatcca atctaaaatc tatttcatta
     7921 tatcctaggc tatttctaac atatctttcc aatctatcta catcacttat attatcatct
     7981 aaatttggtt cttccatttc tatgtatttc ttttttatat ttgttttaaa ttgaaggtta
     8041 tgttcttcaa ttattttttt agctctttca aaaatttccc tatcctcttt tttattacta
     8101 ccttctatct tcataccatg catagaagat gatactttag aaggaacttc aatttctata
     8161 tctgatatta cctttgtaca acaagctagt atataacctt gctcccactc atcatctgtt
     8221 atatgtcttg ttttttctgt atcaactttt ccattcaata attttacttt acacttccca
     8281 caagacacgt ttccattaca aggagcatct atgaatatat ctgcatttct tgcaacctct
     8341 agtaatatat caccctcatt acaataaacc tctttattgt ttggtgtaaa actcactttt
     8401 atcatgttat ccctcccaat ttgttctata tatgataaaa ggaaagtata gctaaatttg
     8461 cgtgcactca aattttacta tactttcccc aattataata atatcttaat ctttaattat
     8521 tctaatccag cctcgtattc tttatcactt aataacgtat caagttcagc cacatcagct
     8581 agttttactt ttaatatcca gttttcatat gggtcttcat ttatacattc tggctcatct
     8641 tctaattttt cattaacttc caatacctca ccattaacag gagatattaa atcagaagct
     8701 actttagaag actcaactac tccaaaatct actcccttag ttacagtatc ttctacttct
     8761 ggtgtttcaa caaacaatat ttctcctaat tgatcttgag catagtctgt tatacctata
     8821 tatacaacat ctccatcaat tacttttacc cactcatgat ctttagagta ttttaattct
     8881 ggtaataatt tcatttcgat agacccccaa tattatatta ttgattaaat tacttaaatc
     8941 atattaatat tatatcatat tattttaaat tttccatcaa ttacattaca ctttccatag
     9001 ctaatgctgg atgacctttt tcttctaaga aagctaatac tccttcagaa tcgtcagcta
     9061 tagtttcatc acaaaccata tcacagaagt tttctattcc agtcatttct ttaactgtag
     9121 catttaattt atcagctaca taatctttta attcttttgg catccaaact attctttctg
     9181 gtccaccttc tgcataagcg aattttttag aagatatgaa atgtcttccg tgtcccataa
     9241 atcctggagt ttgaactcct ccacctgtca tagaagcaag ttctccgaaa gtcataccaa
     9301 ctggagtaac acttgcaaat tctctgttaa ctacaacaaa tccgtttgct tctggcatta
     9361 taccacagat acattcgaag catccacaag aagtcattgg gtcttctagt atagaatata
     9421 atgtaacaga ttcaactgca ccttgagata tttggtttac agtttcattt actgaattcc
     9481 atacacctgt tctatcatct aagcactcgc ctttttctat tggttgacaa ggacctgttg
     9541 ggtctaattc tttagtagcc ttagcatcta accagctaac tgctccacaa agaccaagtc
     9601 tttcaggagt aacaacacaa acgtgagctg gtgcaaatga ttgacataag ttacaagaat
     9661 agaaagtatc aacactttca tcaactaatg aagctaatct ttcatctcta gcattgtact
     9721 tagctattgc ttctcctttt aattcagaca ctttttcagc atctgtaatt atagttattt
     9781 cacacttatc aactactgat tcaaattcat ctaacatctt agcatataaa acttctccta
     9841 tatgctcaag tctaaatcct ttatcaaatg catctttaga gattcttacc caagccatat
     9901 ctctttgtcc aacgtgcatt acaccttcta tatagttcaa gaagtagtgg aaacgtcttt
     9961 caagaactgg ctcgaaatct tcttgcatat ttttaccagc tattttaact attacagcaa
    10021 gcggtaatct taatacacca tctgcatcaa cttcatctat atttggtcct attatttcta
    10081 tcttatggtc ttcaacttct gttgcttctt tcttaacaac aagctcccaa gcttcagttc
    10141 tgtttccacc aaactcagca aacatatcgc tctttctaat tctctcacct tcaaatgctg
    10201 ctgcaaatga aactgggata ggtatttcag taacttttat ttttattcct ctagcttcta
    10261 atgaagtagc tactatctta tcgtaatctt tttgagttaa taggttcatt ggaacttcaa
    10321 gaactgtttg gtcagttata actgggaatc ctaaagctat tgctccagca cctgcagata
    10381 caactaattc acttaatggt ccaaatgcat taacaaatgc aggaactcta ttagctgtgt
    10441 actctaataa tccgtttaaa tcaccaggag ttaatccacc gaatattaat gctgctctta
    10501 ctgcaacaga tacaacgtgt ataacagaag ttacatcata tcctagaggt ataactctta
    10561 gctcaagacc catttttact ccagcttcta tagcttggtc tataacttta ccaactaaga
    10621 aagttagtaa acctttagat tggtaatctt ttataacttt tgctgctgat tctgcatctg
    10681 gacactcacc aagaacaact gcaacaccag gtatatctcc tgtaactaat ggtacaccaa
    10741 gtgatctgat tatagggtca gttatatgac ctgcacatgg ctcactatat ggagcatcca
    10801 tagttgaata ttttaatgct tcaattactt ctgcagctaa agccgtagct aaaccagcat
    10861 taaaagcatg ttctagtaaa tgagttctat ttattaaaga ttttactact tctaaagcac
    10921 cttctaagtc ccctaaagtg ttcatctttt gtcctgttgc agcatatata caaggtaatg
    10981 aatatgctgt atcagggaaa gcaactttat gctcttttcc attcttttct atagcttcag
    11041 ctaacatagc ttgagccgca cctaaagctt gttctgaccc tgtaaagatt atattatata
    11101 gattcattct atttccccct ttaatattta cacctatttt ttattaacta taccctaaaa
    11161 accctagaaa gcaaatccac cttcatttaa ctctaagaaa gagtctgcat ataaagatgc
    11221 cccgttgatt atgtcacaag attttacagt tttcattaat tctgggtcac atggattcat
    11281 tatagctgaa ctaaatccat tagccattgc cattgctaag aatgcactat ctaaaacagg
    11341 tctaacatgc ttaggacatc cattagatac gttagataat cctcctgtag ttaaaagtcc
    11401 catctcagtc atcattttta tagcttctaa aacttctact tgtttttctt gcataccttt
    11461 tataactaag cataatgggt caaatagtat atcagttggc tccattccta acattaagcc
    11521 tttttctaat atttcttggc agtaagccat acgctcatca ttatctcttg ggataccttc
    11581 ttttgcacat aaacctataa ccattgcttc gtattcagct gctatatcta ttaaatcaaa
    11641 tcttgagcca gcatcagcag agtttattat tggttttgca ttagttctat cataaacttt
    11701 aagtccagct tcgatagctt ttttattagc tgtatctaat gctataggaa cattgttgaa
    11761 ctcagattga agtaatttga ttccccatgt cattatttct tcgccatctc tttcggcagg
    11821 tcctatatta aaatctatat agtgtgctcc tgcttctaat tgctcttttg ctctttttaa
    11881 gattggagct gggtctcttt ctgctaatgc ttttcttatt gaaggtgata tacaatgtat
    11941 tctctcacct ataatcataa atttttccat ttataatgtc cccctttaaa tttaatatta
    12001 atagttagtt aatattttat tagtttgttt ggcatgcttt ttcttggtat ccttttaaga
    12061 acttaggtaa ttccatagat tcctctggtc ctataactac attccatcct ggtaagttat
    12121 cttctatatc acctttaagt actgcaactt ttcctggaat gataaggtct ttacaattag
    12181 ttacttcttc taccttactt tctttaatga aagcagagat tgagtttcca ccaaatttac
    12241 cagcagccca agatgtaaga actgaatatc cacctgcatc tggtattact aaccatactg
    12301 gaacttttga tctttctata tcaccagcaa ctatgaagta agttaatgca aagtcaacag
    12361 taactaatac tggagaattt tcatctgggt tgttgattgg ataaatcttt ggttcaactc
    12421 tcattggtct ttgtgggtca gtgtatatgt tttgtcttag tgcaaataat ggtaatgcct
    12481 tagcataact aatatcatct attactatta tagaaccgta ttttatagtg aatattgatg
    12541 ataaagcaac ttccatcata gggtttgaat tagataatct atttgcaaat actattgaag
    12601 gatatccaaa tgttctatct tgctctttta aagctgttct tctaacttgt atagcattag
    12661 tgtaagtatc ttttatgttt tctcctgtta catctaatac taattcttta tatccagcgg
    12721 cttgaattaa ttcaactgtt tcatataatt cttctaagct accagctttt acacctaatg
    12781 gtaaacttgc tcctttaact acttctatca tatctttgta gttctcttta gttgctccat
    12841 ataccattgg tctagcatct tttaatactt caacagcttc tttaactact tgtgcatcat
    12901 cacaagctaa aatataagct acttctaatc cactgccttt tattttatct attaatttta
    12961 aatacgcatc tttatctcca caatactcta aaacagccat ttcaactttc atttgttcac
    13021 caattcttac atagtcaact tttttcatgt tagctatttt agcatctact gcttcatcac
    13081 tcatacaagt acagaatgaa actgcatatc tatttctact tactaatgtt ttttcatgtc
    13141 taaataatac tgtttctcca cctagttcat actcagatgc accagcacca acttttaaag
    13201 ctttcattaa aggtgcagta gcctctgata attttgctat agcgtcatca gacatatgtg
    13261 ggcatttacc tacttctaca gctcctgaag caaccttcat agagaaagcc atacaagttg
    13321 ggaatccaca atccttacag tttttctttg gtgttaattt aaatatatct aaagctttta
    13381 atgccattat tttttccccc taaccttaac aatttaatta agctaatgcg ttaaccaatt
    13441 cttttatagt ttctattgat tttggatgac gaagtataac tgcgtttgaa ccacctacta
    13501 aaacacttgc tgcagttgaa acttccattg ctatagttct ttcttctgga caaccccaat
    13561 ctggctcatc ttctattgga gctatagctt ctttaacatg acctacttca aaagctactg
    13621 gtgttatgat aggcatttgt aatgtcttat cattttgacc aaatgctgca agtctaattc
    13681 tatccatagt agatgcaacg tactcatatc cataaccaac tgctgaacat ccaacattca
    13741 taactatatt ttcaccttta acgcctagtt gagttaacaa tacgtttaat tgtttagcta
    13801 ggtttatatc aacagaagat tcagctccta ctttatgtgc ataagccata ccagctgatg
    13861 ctcctactcc tttgtagtta tcttctactg ctgacataaa taagcagtta tgtccatcca
    13921 atgtttgagc taatttttca aataatttac catctttttc atgatttcct gaaccagcta
    13981 caactaaagg taattttatt gcttcaatta ctgccttagc tacatcagca cattcatcaa
    14041 ctgacttatc taatccattt gggtcagaac catcaaattt taaacaaata aaatctgctt
    14101 gtgtattagc ttcaacatat ttagcccact ctactggaca attagctaca tctttgtata
    14161 attccttata tgaatcagtc cagctttcag gataaacgtc tgatatttgt atacctattt
    14221 ttggagaatt acctacttct ccatcaaaac tataaaaagg taatacattt tccccaccta
    14281 atttaattgc tttttcccct attcctactt caacttctga tatttttcca gaatattttt
    14341 gagtagacat tttaaatgcc atattttttt cccccttaag cctattttaa ttctaattta
    14401 gcaaaaattt ctttcatagc cactttagat tttgaatctt caggtaaatt aactaaagga
    14461 atacctgtag aatcatattc atatatcaat tcatccatag gtacaacacc gattagctct
    14521 aggttatgct tttcaatttc ttctttaaca ccatcattca taaccccatt tggaacttta
    14581 tttacaatca aaagtattct tccaacactt aactttagtt cctcagctaa atctcttatt
    14641 ctagcaacag cttgtatgct acgtcttgag caatcactaa ccaataaaag tgtatcaaca
    14701 tgtctagtga cttttctact tagatgttcc ataccagctt cgttgtccat gactaagtat
    14761 ttgtaatgac cagatatttt gtttacttgt tctctaagta tcccatttac aaaacagtaa
    14821 catccttcac cttctgacct acccattact aataagtcat atccttcgcc ttcttcgatt
    14881 atagaattta atctaaattg aagatattgt gcctttgtca taccaccagg gaatgcattg
    14941 cctaactttt ctctttgatt tacttcttct cttatttctc ctattgttgc ttcaacttcg
    15001 atacctaaca cttcatttat gttagcattg gcatcagcat ctacaactaa tactggtccc
    15061 tttttgtcct taaccaaata atcaattaaa agccctgtga gacttgtttt accagttcca
    15121 ccttttcctg caacagctat attgtatccc attttaagac ttccccctta aatctagcca
    15181 cagagcctta tgtactctgt ctgtctatta taatttaggt acagaatgaa cacattctcc
    15241 atgtacatca tgaagtgctt ccattagccc ttcagataaa cttggatgtg gatgtattgc
    15301 atcccctact tgttctactg ttaatcctag atgaacagca agtgacaact ctgtcaataa
    15361 atctgtagca tgaggtccta ctactgctgc acctattatc ttatcagttt ctttgtcagc
    15421 tataactttt acaaatcctt ggaaatgtcc tatagcttgt gcttttccaa gacctctaaa
    15481 atcaaattga cctacattgt attctacacc ttcagcttca agttgctttt cagtcttacc
    15541 aacaccagca acttcaggtt cagtataaac acatcttgga attgctctat aatctactac
    15601 cttagtctta cctaaagcat tttcaactgc tacgatacct tctttagaag caacatgtgc
    15661 taggaaagga gtatctatta tatcgcctat tgcgtatata ccttctacat tagtttcaag
    15721 atgttcatta actactactt ttcctctttc catttcaatt cctatatctt ctactccaga
    15781 attgtcaagg ttaggtcttc taccaacaca tactaatgca tattgtgctt ctataacctt
    15841 tccattagaa agagttgcaa ccgccttacc atcaactact tcacaagttt gtactccaat
    15901 acctgtaata accttaattt tatctttctt aaattgtcta agtagttgtt tagctacatc
    15961 tttgtcttca tttaatagta tttggtcaac catctcaact atagttactt ctgttcctaa
    16021 ggctctaaag aactgcccta tctcacatcc tataactcca ccacctacta ttaacataga
    16081 ctcaggtatc tcttcaagtc caagaacttc atcactagtt attacaactt ttccatcata
    16141 tgggaacatt cttggtacaa ctggaacaga accatttgct agtattatct tatctgcttt
    16201 tatagtttct actgttccat catctttagt tacttctata gtgtttttat caattaattt
    16261 tccaaaacca ttaactaagt ttactcctct tttttcaaat aagaactcta taccacttat
    16321 taattggttt acaactttat tttttctttc cattatggca gtgaagtttg gcttaactgt
    16381 accatctatt tctataccaa aatcctttgc ttcttttaca gtattcaata ctcctgaaga
    16441 agcaagaagt gctttagttg gtatacatcc tgcatttaag caagttcctc caactcttct
    16501 tttttcaata accgttacat ctgcaccaag catagaagct tttatagctg ctacatatcc
    16561 tcctggtcca ccacctacta ctactatctt catccttaat tcccccaaac ctaatataat
    16621 ctacaatctt gcaatactat aaacctgcgg catccagtat agcaggtata ttctcttctg
    16681 ccccaattgc cattatatga acaccatcac ataaatcttc ttcttttaat tgtttgataa
    16741 gttcccctgc catttttatt ccttcactta cccagttttc ttttccagct gctcttaatc
    16801 tttcgatttg ttcatctgga acgaatattc ctggtacatt tgcagtcata aatttagcca
    16861 ttcctggtga ttttaaaggt actattcctg ctaatacctt gcaatccata tcccttgtta
    16921 attctctaaa ctttctcatt gtatttatgt cataaagtgc ttgtgtttgg aaaaatttag
    16981 cccctgcttt tatcttcttt tgcattttta ataattgaac ttctattgga gaatattctg
    17041 gagttactga tgctcccaga taaaaatctg gagaaccttt taacttatta ccagccatgt
    17101 ccgtacctgc cattaaagtc tcagcagttt gaagtatccc cacagaatct aaatcaaaca
    17161 ctcccttagc ctgtggatgg tctcctacgc tagtatggtc tcctgttagt gccaacaaat
    17221 tgtttatccc aaatacacct gctgacaaca tttctccttg tatagctatt ctatttctat
    17281 ctctccctgt tatttgaata actggctcta atccagcatc ttttaataat ttacatgtag
    17341 caagagaagt tgctctcata actgccgatt gaaagtctgt tacatttgct gcatgaactc
    17401 ttccaactaa cggctttgca cattctatta aatgtgaaag gtcagtccct tttggaggag
    17461 ccatttcagt agtaactgca aattttccac tttctaatgt ttctcttaat aagctcatct
    17521 ctaatccccc ttttaacctt ctaaaaaaaa cttttatgaa tttgctgctg cttctttctt
    17581 tttctttgca cttaaacttc ttggattatt ttgcttagaa tagtcttttg gtggtcttat
    17641 ttctgctaag ttatctaatt gtcctatagc ttctagtctt tcatatatct ttatccaagc
    17701 acaatcattc tctgagttta cttcacactt accattttta gctccaccac aagccccatt
    17761 cataagacct ttagcacaca tagttactgg acatatccca cctgtccaac caagttcaca
    17821 gtctccacaa gccttacagg cttcttcata ttctccaact ctttgtactt cccctataaa
    17881 caaagtattg ttggctggat aaactggctt atcttttaaa ttcttaacta ttgtctgtgt
    17941 accatctcca catgctaaag ataaaactgc atcagcttcc ttagtctctt cttttagagc
    18001 ctttaaatcc tttttagact ttaaaaggtt acaagcaggg tcaagcatta catatcctaa
    18061 gatttttttg ccttcacctt caagagtttc cttcattttt aaaacttctt cttccccacc
    18121 acttttacaa gttgctgcac attgattaca accaactaaa accagcttgt caaaatcctt
    18181 taagtaccct agcacttctt ctaatggttt attttcagaa attatcatat ctacttcccc
    18241 cctaaacctt ccacatatat atctctattt attgttttgt aatttacaag ccttaactac
    18301 atgttttgca agtatagatg ttgtaactga accaaccccc gctggaactg gagttatcat
    18361 tgatactttg tctaaaactg catttgtatc aacatctcca cataaatttc cttcttcatc
    18421 aacatttata ccaacgtcta taactaccgc tccatcttta acaaaacttt catcaaccat
    18481 cttagctcta ccaatagctg ctattagcac gtctgcctct gctgctacac ctgatagatt
    18541 tttagttttt gaatgacata ttgtaacagt tgcatgttca cttaataaaa gcattgatac
    18601 tggctttcca actaccattg atcttccaag aactgttacc ttacttcctt ttaaatcaac
    18661 attatagtgt tttaatatct caactactgc tgtaggtgta catggtggaa atccactttt
    18721 atccccttcc attaccttag cagagtttat tggactaaaa caatctacgt ctttttccgg
    18781 tgcaataaca tattttataa cttcttcatt taagtgtttt ggaagaggtc taaaacataa
    18841 tataccatta acatttttgt catcattaac tctctttaat acatcaatat attcctcttg
    18901 tgttatatcc tcagctaact ctaacacttc tgttgttata cctatgtttt gacatctctt
    18961 tagtgctcct ctttcataag ataaatcatc acttcttgcc ccaactctaa ctattgttag
    19021 tttaggattt ataccttctt taactagtaa atcgacttct tttattaatt cttcactaat
    19081 tttatcagct acaggttttc cttttataat ttgtccttta gttgacattc cttccataca
    19141 ttcacaactc ccctacaagc aaacttaaat taatttattc tatataccac atattaataa
    19201 catagtatct actttcgtca tttaaaaatt attttccaag agctttttca actttggcat
    19261 aaacttcatc acaaattttt acaccatctt caactaactt atctacttct atttttacct
    19321 tattaacata ttctttatct tgtatagaat ttatatttat aactacattt aattgtccac
    19381 caagtatagc agctcttaaa cactgaactc ctacaccaac atcacttata gcaagtcttg
    19441 aacctttatc aactaaatct tcatgtaact taatagcttc atagcaaact cttactatgt
    19501 ttaatggtac ttcacaagca acttttaatg ccttttccat tgtttctgct tttattcttt
    19561 tttcttcttc tgtttcttta ggaagcccgt aagcttttga taatggtaag aaacattctg
    19621 catcatcatc tatcattttt aataaatctt tttctaactt tcctgcctta cttaatatct
    19681 cttttacgct ttcttcatac tcagcatact tcttcttccc tattgtaagg ttacatacca
    19741 tactacctaa agccatacct attgcaccta ctagtgcagc agctccccca ccacctggta
    19801 ctgcttcttt ggaagatagt acttctacaa aatcaacaca agttttatct gctattttca
    19861 tgataatcct ccttgaaagg atgtaggaaa atatctcaaa ttattcgaga tattttacga
    19921 actattttaa gatatctcct actctttatt tataaattaa tttccttaga ataatccagc
    19981 tattactcca ttttcatcaa catctatttt ttctgctgct ggaacttttg gtaatcctgg
    20041 catcttcatt atttctccag taagtgcaac tataaatcca gctcctgctg aaattgttgc
    20101 ttgtcttaca gttattctaa atcctgttgg tctacctaat ttagtttggt catcagttaa
    20161 agaatattga gtcttagcca tacatactgg aactttagta aatccaagtt tttctaagtt
    20221 agctatttcc ttatcagctt caggagtata atctacacca tctgctccat aaatcttagt
    20281 agctatagca tttatcttgt cttttataga taaatcatct tcatagcaga atctaaagtt
    20341 attttcttct tcatccaata atcttaaaac ttctttagct actgcaattc caccttctcc
    20401 accttttgcc catacttcag aaagagcaac attaacacct aattccttac acttgtcttc
    20461 aacaagttta agttcagctt cagtatcaag tgggaatcta ttgattgcaa caactgctgg
    20521 taatccatat acttgagtta tgttttcaac atgttttaat aagtttggaa gtcctttttc
    20581 aagagcttct aggttttcgt tatttaagtc tgctttagca actccaccat tgtattttaa
    20641 tgctcttaca gtagcaacta ttataacagc atctggtttt aagtttgcca ttctacattt
    20701 tatatctaag aatttttctg ctccaaggtc agcaccgaaa ccagcctcag ttattacata
    20761 gtctgcaaag tgcatagcca ttcttgtagc tataacagag ttacatccat gagctatatt
    20821 tgcgaatggt ccaccgtgta caaatgatgg tgttccttca agagtttgaa ctaggtttgg
    20881 ttttaaagca tcttttaata atgcagccat agcaccatta gcttttaatt gtctagctgt
    20941 tacaggttca ccttcatagc tgtatccaac tattatgttt cctaatcttt cttttaaatc
    21001 agatatatca cttgccaaac agaacgctgc cattatttca gaagcaacag ttatatcgaa
    21061 tccatcttgt ctaactgctc catcaccttt tttacccata ccatcaacga tatttctaag
    21121 ttgtctatcg ttcatgtcca cacatcttct ccaagttatt ttcttagggt ctattctaag
    21181 tgcatttcct tggtgaatat ggttatcaag catagcagct aaaagattgt tagcagctcc
    21241 tatagcgtga aaatctcctg tgaagtgtaa gtttatatct tccataggaa caacttgtgc
    21301 atatcctcca ccagctgctc cacctttaac accaaatact ggtcctagag atggttctct
    21361 taaagcaact aatacatttt tgtctagttt agcaaatgca tcagcaacac ctatagtagt
    21421 agtagttttt ccttcacctg ctggagttgg atttatagct gtagttagta ttaacttagc
    21481 ttttttacca gtctctcttt ttagtagatt gtagtcaact tttgctttgt atttaccata
    21541 aagttctaca tcatcttcac ctagtcctaa tttttttgca acctctctaa tatcttgagg
    21601 cttagcttct tgagctattt caatgtcaga tttaaatccc ataactgaat ctcctcccac
    21661 aacctaaata gatttaaaat ataatttttg taaaaattgt attaatatgt aaaaattata
    21721 ttttataaga taattataca tgtaaaatta cttaaaaact agctactaag ctattaaaat
    21781 attcaaactt aatagctagt tatttatcta attacttact tattacctat ctattgccta
    21841 tgtctaacct ttaaccaact taaaatccca aatcaaaatt tctatctatt ttatttatcc
    21901 ttaagtgaca ttaatttatc ttttattgct ttaatctgtt ctttcgttgt ttcactagaa
    21961 tcatatggag attgattagc tctatcagaa tcaataacat cttggttata gtaaataaat
    22021 cctaaagatt ctccatcttc taagttttgg attataaatt cttcatcttc cttatttcta
    22081 attttatttc ctactacaaa tactttattt acacctatat catgtccaag tttcttaact
    22141 tttctataag tctgtagact tctctctcct ggttctacaa ctactataaa agcatctaca
    22201 ccttgggctg ttcctcttcc taagtgttca attcccgctt ccatatccat aaccactaca
    22261 tctttatttt gtagtattaa atgtgagcag agtctcttca aaagaacatg ctctggacat
    22321 acacatccag taccaccaga atctacggtt cccaatgtaa gtaatcttac tccattgtat
    22381 tctttacaga aattttcagg gatatcgtct actttaggat tcatcttaaa catttttcca
    22441 aatgaaccta cagaagcagc tgttctatct gaaactaatt ttttcatttc tgatataggt
    22501 actattgatt catatacttc ttttggaaaa cctagtgcta aagctaaatt agcatcaggg
    22561 tcggcatcaa cagcaacaac tctgtatccg tcttcagcaa acatcctaga gagcattgaa
    22621 gaaaaagtcg ttttacctac tccaccttta cctgttattg ctatcttcat aatccctacc
    22681 accttttatt actatttgct ttttagtagt taattttaca gttaaatatt ttttatactc
    22741 tatattttta tacactaaaa ataaactaca gctagtcctt acaggaacca attaaattta
    22801 ccctactagc ttttcaaagc agcatgtata gttttattat tctttaatat tgtttatatt
    22861 ttatttattc agtatattca ttatatttcg atgttcttta ctttaatatt tgactttatt
    22921 caactttact caaccagaaa cttcttataa aaacgtttat tctataactt cactattttt
    22981 taagcttcag ccttttctgc cattttttct tcaactaatg cttcaaagtg aacacgtttt
    23041 ttctctatat cttctattat tgtagctgct aactcttttg gatttgtatt tacagtaaat
    23101 gtagctccaa ctttatcttt taactcacta gttaatatat ccactgctct tgaagaacca
    23161 gctattggag gcattattcc taaataagtg tctataccag aagctacaac atagcatcct
    23221 atagcaactg ctttttctga catccattct ggagctatac ctacaactgg aaggtcacac
    23281 atatccatat ctaagtaatt agctgctgct ccaactaaat ctagtatacg acttatatca
    23341 acacaagaac ccatatgtag tactggtggg attcctacta atttacagac agttgcaaga
    23401 cctttacctg catatttttc agccgcatca gattccatta aaccaaactt agctgctgct
    23461 gaagctccac aacctgtagt aactactatt atgtcgtttt tgattaattc tttcattatt
    23521 gttacgtgag cctcatttga aactccttta gcattgttac atccaactac accagctgct
    23581 cctcttaata ctccagcttt tagacagtct gttaatggct taactgttcc tgctgggtct
    23641 atatgagagt ttacaactct gtctaattga tttactactg cttctacact atacccaact
    23701 gttgcgcctg attttaattc aggtataagt acttttgatt tatctctatt tttaaagttt
    23761 aaaatagctt ctttaactat tgctttagca tcatcaagtg cttgttcttc tctaaattca
    23821 atataagttg aacctgttat cttagctttt ggagaagttg ttacaaattt agtatggtaa
    23881 caatctgcaa ctctagctaa tgcagggaat atacattgaa cgtcaactat tacagcttca
    23941 actgctccag ttattattgc aagttcttgt tgatggaagt ctcctgctat ttttacacca
    24001 tgtctcattg taatctcatt acctgtacaa cacatacctg ctaagtttat tccatcagca
    24061 ccaacttctt tagctaaagc tactaagtct ggctcttctg atgctaaaac tatcatttct
    24121 gataatgctg gctcatgtcc atgtaatatt atgttaactt tattttcttc taatactgct
    24181 aaattagcct ctgttcttct tggcactgga gttccaaata agatatcgct tagacgagta
    24241 cctatcatag aaccacccca accatcagcc atagaagttc taagactcat gtgtattaaa
    24301 ctatctatat caccagtaca tcctatatga gtagagtgca ttattgttgc aatttctcta
    24361 tctatagctc ttggctctat agcgtattct ttccatattt tttgtcttgg ttctggtgca
    24421 ttttttataa atcttaatgt cccaaaaggt tttccaaatt ccattaatgc aatttctgcc
    24481 acttcatgtg ctacatcata gatatctcta ccttctgtct ctacatccca ttctttagct
    24541 aaagtaatta acttagcttc gtctcttatt ttatagtttc catttggatc agctaatgct
    24601 aatgtatgtg ctatatctct agcatggtct gaatgggcag ctgtcccacc agcaaccatt
    24661 cttgcaaagt ttctacctac tatagtatgc tcatctgctc cacataaccc ccttggagtc
    24721 ttagggctta ttctacatgg tcccattcca catattctac agcaaacacc ttgaagacca
    24781 aaaccacatt gtgccttaaa gccttctttt ctatcataca ttgtttctac gccttcttct
    24841 ctagctttag ctatcatctt ctggctgttt aaatcaattg ttaacatttt ttcatccata
    24901 ttcctatccc ctttttttga tttttaaaat cccccaggtg actgacttca tgtcataaaa
    24961 taataaaata aatgctttct aagttgatta tatactaatt ttcagtgctt tgctttagat
    25021 ttaaatattt ttttaacaaa attagataat acataaaaat tttattttct acacttaatt
    25081 taagttgatt ttatcgcttg tttttggcta tttgttaata tctaaaccta cttttttgat
    25141 acttcagttt aattaaatta tgttttgatt tttttaaatc aaatttgaaa tttttctagt
    25201 catttttata ttattgcaga ttgtttgtgt atttattatc tttcactact gtttggactt
    25261 attacagatt tttactccct aaacttaatt agtaaaaact tcttagaata gcattttttg
    25321 gactaatttt tttgaatttt tttatttttc ctactttaat attaattata gcttcaaatt
    25381 gaacatttgt atatattcat ttgaagctat aattattttt tatataaaac ttttttaata
    25441 cagcattaat ttagacattt tgactatttt ttctacttta attcatttat ttcaagcgat
    25501 ttatcctatt tcatattttt agctacaata gccccatatg caatagaata taatttagat
    25561 tcatgtgaat cagctcttga cactaaaact ataggagctt ttgcacccat aattatacct
    25621 gctgatttag agtctgccat atatgtaaag gctttcccta ttccattgcc aacctctatt
    25681 gttggaacca atatgatatc tacatctcca gatacttcac ttttaaaccc ttttatctca
    25741 ctagcttctt ttgaaacagc taaatcaaaa gccagaggac cttctacaat tacattttca
    25801 ccaaattctc cttctttaca agcttttgct aacatatctg catctacagt tgcttgcatc
    25861 ttaggattta ctttctcttt agctgccaaa catgcaactt ttacagtttc cattcctaaa
    25921 gcttttgcag cttttataga attttttaat atctttgcct tttgttcata atcaggagct
    25981 atattcatac ctccatctgt agttataagt aatttatggt atttttctaa ctcatatacc
    26041 ataacatgac ttaataaact atcagttcta agaccatagt ctttatttaa cacttctttt
    26101 aatatgacag atgtatctaa taatcctttc attacaaagt cggcttcttt acttgatact
    26161 aatttaactg ctatttctgc acactctttg atatcatcct tatccactat tttgatacca
    26221 cttaaatcaa atcctatttc ttttgatatt tctcttattt tgccttcatt tccaaccaat
    26281 ataggagtaa ttatatttct ttctacagca tcctttattg ccattaaaac ttctttatca
    26341 tgagctgctg ctacagagag tacaattttc tctcctccct taagttgttc taaaatatca
    26401 tctaattttt ttatcaaaag taacccctcc cttatatata tttaactaaa taataccata
    26461 tttgctatac cttttctcaa tttatttttt atgttataaa gaatttatat gactaaaaga
    26521 cagtttaata ttttattctg ggatttcatc aatagctctt aaaagctttg caggaacacc
    26581 acctacaata gtattttttg ttacaactgc tccagcagcg ataattgcat tatctccaat
    26641 agtaactcct ggaactcttc atacaaaaaa gaggcttatc tctattttga gatagcccca
    26701 cttaaccgat aaaattaaat acaacctaac aatatcctta cttatttatt ccaagttctc
    26761 ttagacaagc aatagtaatt tcatcttgtg gatttaattc ataagctctt tctatatagt
    26821 aagttgcatc atcaatatca ccattattta aataagccat tcctaaattg caaagtattt
    26881 ctgggtcttc ctttatctta gccgcttgtt caaaatactc tattgcttta tctaaattat
    26941 tcttataagc ctcacaaagc cccaattcca ctatagtatc cacctgatta ggctttatta
    27001 tcaatatctt ctcaagatac atcttagcct gctctatttc gcccataccc ttatatccaa
    27061 gtgctatcat aaacagcaag ttccaccaat ccatatgttc ttcttctaat ggaagtaact
    27121 tctctaatcc ttccttaaac ttaccttgga atacaagtgt atatccttct tcatattgaa
    27181 ctttaaagtc catcttgcct agattctctt gtacctcagc tactaaatca gcatctaacc
    27241 ctagccttaa tgcttcttcc caagtcagct tagtctttaa atattgacct tgattataat
    27301 aatggtagcc taagtgataa taacctaatg caaaattctc atcaacatca attacctttt
    27361 caagcttagc catggcttca agtaagaatg cattcattgc cttatcatcc atatcttttt
    27421 gatactgttt agctatctct tggcaaacaa tcgcatagtt atacattgca tctaaatcat
    27481 ctggatacat tgttataaat gcttttatat atattaaaga atctgtatgt tcaccaatct
    27541 caaagtattt tctcgacata tatcccatat acgatttcaa atccaaatca atatcttttg
    27601 ataaagcatt taaaaacttc tcatactctg cattgttttt aaacttacta tctattccaa
    27661 ttatatatat cattgcatct gctatagaca ttgaatttaa cttatcttga gcagtctttt
    27721 cttttatccc ttttactaat acctcatttt ttataggtac atctaatccg ccttttggca
    27781 ctttatagct ttttaattta aactctccac catgttttat agttataaaa gctaattctt
    27841 ctgctttttt tagcaaatat ttttctatct taaaatccat tttatcctcc taaatactta
    27901 aatctctact ttatgagttt tagatttctc aaatattttt ttatcatcat actcaaataa
    27961 gactacattt tctacttctc ttatttctgt atttatatca ttttttaaat ccacaacatt
    28021 aaatctaaat ggctcaaaat gaacatattt tattatatgt ttagctggtt tatcaacaaa
    28081 actaggtaaa tatgttgata agttatcatt atcttgtaaa aatacatggc atctattctt
    28141 aaaatcatcc acatctagct tattaaaaaa ctgtggtata tttgatgttt tacccagtga
    28201 tatatagtca tattttaata tatcattgaa tacatcatta tctatgttga ttttttcatt
    28261 atagaaatcc atcaatattt tatataactg attctttcct tgtgccaaat caaagtagcc
    28321 attttcatca aaatacttgg caaaaacctc aaagaattta aaaggacttt gtttataaaa
    28381 tctgcctata atatatctca tagataacac aaagttttta gaattgtagt atctctccag
    28441 tatatcttct atatccttta gcttcaaagt ttcttcatag cttatataat tattgtataa
    28501 aaactcatat ggagcataat ccttatattt aaaaccatgc tcatctgcaa cttttctcat
    28561 acctgtccct ttaatcatct ttaaaaagcc taattgcaga tgctctatac ctagattaaa
    28621 tacatcatta aaagaatttt caaagctctt ataatcttca taaggcagtc ctgcaattaa
    28681 gtctaagtgc tgatgtatat ttctataaga tgctacagtt tgtacaacat gagacaactt
    28741 tttaaaatca tcccttctac ctactgcatc aagtgttttt tcattcgttg actgaacccc
    28801 tatttcaaat tgaaaaagac cttctttaca atcagccaaa aactcaagca tcttatcatc
    28861 tatcaaatac gctgtaactt caaaatgata agttgtatat ccattatcat ttttcataag
    28921 gaaatccatg atttccatag ccacttttct atttgcattg aatgtcctat ctataaactt
    28981 tatctgtgat actcttgcat ctattaaagc ttttaaatca ctctttatcc tgtctaaact
    29041 aaaatacctt agacctggaa tagtagatga taaacagtac tggcagttaa aaggacaacc
    29101 tcttgatgat tcataataca ctattctatt ttcatattct tttggattca agttttcata
    29161 aggactagga atctcatcca aatcttgaag taattccata ggcttattca ctattatctc
    29221 attgccttgt ctatatacaa gtccatttac atcatttatt ttcatctttc cttgcaagtg
    29281 aagtactaag tctctaaaaa ttaattctcc ctctccataa agtatataat ccacaaaatc
    29341 atactttttc attgcctcat aactatcata actcacttcc ggtccgccca aagctatttt
    29401 agtattaggt ctaatttttt ttagattatc acaaagttta actatatctc ccacattcca
    29461 gatatatgtt gagaataata ttatatcata ttcattttta tatatatcct ttaaaatata
    29521 gtccaaatcg ttgtttatcg tgtattcttt catattaact tctatcaaat ctcttacaaa
    29581 ttcttttaga tatcttatag ccaaatttgt atgaataaac ttggaattta atgttgttaa
    29641 taaaattttc aaatatttct cacctctttt taagattata ctgtcttttt gtacccctta
    29701 taggttaaaa tagtatatgt aaagtctaaa taatatctat ataattaatt tattaatttc
    29761 aagtaatgtg aggaaaggaa gttttttatg gaattaattg aaaaagtatc tatcaactct
    29821 ttatcaaaaa gagatttact acttattata aagtctcttg aatacactaa tgaaaatact
    29881 caaattagtg atttcattga ccttaggaat aatatagtaa aggaattatg ttttttaact
    29941 gacactaagg aaaaagattt tttagattat ctagaaaaaa atagcacact ctaataacct
    30001 aaaccttttt aaactttaat atataaatac ctgatttaga atttattttt atgcttaata
    30061 tattatcatt aaaggttttc gacataactg ttatttgatt aaatataggg tctattatag
    30121 tattaccttc ttcaagtctt ataagacttc ttgggtctat gcttttatta tatgccttaa
    30181 ctccaatttt atattttctc aatttaacaa catattcgga catagaaaaa ataaaatcta
    30241 tattatcttc atttaattta ctatcttcac ccaaaatgga taatatagat ttttttatgc
    30301 tattaattcc ttcattttct acagttctat cttccatata tacatcatat agaacattta
    30361 aaacatttaa taaaatactt tcttcatcat aatcttcaga tttcaaatca atgtacttat
    30421 caattaattg tattgcttta atccttgcca tctgaaactt tacaacatct gatttgtcta
    30481 attctataga aaatcctatt atcttgtctt taatactctg tagtaattcg acatactcta
    30541 ttttactatt atttataaga ttgtgcataa tggaattata cactacagaa cctaataaat
    30601 aatcaaataa aagttcttct tttttaaaat aaataacata cttttttatt agtttaataa
    30661 cctcatcttc gcttttttga atattagtat ttgataaaat tagtggtagt aaaatattta
    30721 aaaaattgat atttcctatt ttttctccat aaaatctata gtaaataagt tcatctctca
    30781 gtctattttc gtctatatac acacatcttt gcgttttatc atctattaag gattttgtat
    30841 ttattatagt taaatcttta agagccctac ttgcactact aaaagaagat gtgtagactt
    30901 tttttagtaa ttcgtcattc ataaatatat cctttctgaa aaattgaatg taaataaatt
    30961 gttattaaaa aaaaagagac agcccgttta agaagctgtc atatataggg ggatagtagt
    31021 gtacaaaaat cattgtaatc tactatctat atattattat acgatactac ttttttatat
    31081 gtaaagcatc agttttcgac atccctatat tttacagtta tacaaattgc gtactaagtt
    31141 caattttatt ctttttattt caacatttta tcatgctaca ttctttccgg agcgtgcatt
    31201 cccaacaatt tcagagaatt ttctaaagtt tgttttgttg ctaaaactaa tgcaagtctt
    31261 gcttttctta tttccaaatt ttctactaaa attggattgt catgataaaa tttattaaac
    31321 gcttgagcta aatctaacat aaatctagtc actatatgtg gctcattttt ctttagagca
    31381 agtaaaatat tcttattgaa tgattctata actctaagaa cttctgcact atcttcatca
    31441 gctaatagac tataatctat atcagaagtc acttctactt ctgcttttct taaaactgca
    31501 cagcatctag catgtgtata ctgaacatat ggtccagtct caccatcaaa actaagcgtt
    31561 ctttcccaag agaaggtata gtctttaatt ctactgttag ataactcttg gaatactact
    31621 gccccaacac ctacttgctt agatatttca tccacatttt tagcatttgg atttttagct
    31681 agtataattt ccttagtttt atctatagct tgatttaaag catcttctaa aaatactact
    31741 cttccttttc tagtcgacat agtaccttct tcaagtgcaa ccataccaaa tccaacatga
    31801 attaaatctt ttgcccaatc atatcccata agctcaatta ccttaaacca ttgttggaaa
    31861 tgtaagtttt gttgagaacc aactacatat atacacttgt caaaatcata agtctctttt
    31921 ctatatattg cagcagctaa atctcttgtc atatataacg ttgaaccatc attcttagta
    31981 ataagtgctg gtggcatttt atactcttct aaatcaacaa ttcttgctcc tttagactct
    32041 tttaaaagat ttttctcttc taatagttcg ataactctgt tcattttatc agaataaaaa
    32101 ctctctcctg ctaaagaatc aaattctata tctaaaagtt tatacactct gttaaactct
    32161 tttaaactct catttctaaa ccattgccat aattcttgtg cttcttcgtc accattttct
    32221 aatttattaa accatgctct tgcttcatct tccatttctg ggtgttgttc agcttcatca
    32281 tggaatctta cgtataattt tagtaattct ggaattggat tagactctac tacttctttt
    32341 tctccccact ttttaaaggc cactattaac ttaccaaact gagttccata gtcacctaaa
    32401 tgatttattc ttatagtctt gtatccttgc gaatcatata tcttatataa agcattacct
    32461 ataactgtag ttcttatgtg ccctatatgg aaaggttttg ctatatttgg agaagaatat
    32521 tcaactatta cagttttatc ttttccaaaa tcactatgtc cgtaattttc tttttcatct
    32581 aaaacttttt taattacagt ttctgctaat tgagatttat ttacaaagaa atttacatat
    32641 ccgcctaatt gtattacttt tgttatctct ccacttggtt ctatactttc cgccaattca
    32701 cttgctatca tgtttggagc ttttctaaac actttggcta atttaaagca tggaaaagca
    32761 tagtccccca tatccttatt tggtggaact tctataagtg cctctatctc ttctttcgat
    32821 aaatcttcta ttttttcttt aaggcaattt gatattgcca ccttaaaatc ttgcattctg
    32881 ttgctcctct ctacattgtt cctggtttat attgtgctta tctctttatg ttaaatcaaa
    32941 tttcgtgttt tttcaagtat ttcattacag tgtaaaacac tttaataatt atgttttctg
    33001 tatatattaa aaatactata attgcagttt ttaatcacac tattattgat tttttataag
    33061 acttttttct attttattgt ttcttgtact atccagttga ctttatatac tttttttaat
    33121 cttttatcaa ttttcataca tcaatattaa ttttatatac atttattttg ctcttttatc
    33181 tatttttata catcaatatt agctttatat acttttttta ctcttttatc tatttttata
    33241 catcaatatt agctttatat acttttttta ctcttttatc tattttctat aaatcttttt
    33301 cactcttaat ttttattcct tcttcttcta acagccttgc tgttatacct ttccctggta
    33361 tctttttacc tgaaaaacta ccatcatata ttagattaca tccacaagag gggctaccct
    33421 cttttagtat tgcttcgcta catacatata aatttgctat ttttagagtt tcattagccc
    33481 ctcttacaaa gttttctgtt acatccttat tatctttagt aattactttt ccatcaacta
    33541 tctcagcagg tggtcttggt gtagatagac cacctaactg ctctgggcat acaagtgtaa
    33601 attctttgcc ttttaaatat tccttgactt tttcattttc attattatcg ccactatatt
    33661 tacaatttat tcctattaaa catgcagata ccaatatcat aaaaatgtgc tcctatacaa
    33721 attcttaata tattcttata caaattacta atgtattctt atacaaatta ttttaattta
    33781 acaattgtta ctcctgctcc accttctcca tattgaccac ctcgttgtga ttttacatgt
    33841 ctatttcttc ttaaaatgtc ttgtagccct gcttttaata ctcctgtgcc tattccatgt
    33901 attactgtta cagactctaa acctgccaca tatgcatcat caagatactt ttctacttcc
    33961 attatagctt cttctaggtt taaccctcta aggtcaactt cattttttac actaccagat
    34021 tttgacctta taatgtttct cgttgattta gttacatttg ttgaaacatc tttgcgtgtt
    34081 ttttgtaaag atttaaaagg tagagtcatc ttcattatac caatttgcac tactgcttct
    34141 tttctctttt tatctactga aactacacta ccattttgat ttaaagttat taccttaact
    34201 tcttcacctg gctttaagtc ttttatctcc ttatttgata cctttggaac tatcatactt
    34261 tttactgttg gctgaagact tcccatagag ctggtcaatt cttttctaag ttcttctatc
    34321 ttacgattct tttcttttga agctctttct tgttcaagat ttctaagttc ttttattata
    34381 atatctactt cttctttagc ttgtcttata attgaaaatg cttctgattt agctttttca
    34441 atcatcttat ctctttgact gaccaatttt tcaagttttt cgtcatactc tactttcagt
    34501 ttttcaatct cttcttttaa tctttcagct tcttctctat cttctactgc tttgattcta
    34561 ttcttttcaa cattctgtaa cacatcttct aaagctatgt tttctgtatt tatatattct
    34621 ttagcacgtg aaatcacata atcacttagc ccaagttttc tagaaatctc aaacgcattt
    34681 gattttccgg gaacacctat aagtaactta tatgttgggc ttaaagtttc tatatcaaat
    34741 tcaactgctg cattttctac acctggttta gtaagagcat aatttttaag ctcactatag
    34801 tgagtggtag ctatacattt agctcctaca gaatttatat cttctaatac tgctattgca
    34861 agggcagctc cttcaacagg gtctgttcct gctcctaact cgtcaaatat aactaaagag
    34921 tctgctgtta cgttttgtaa tatagatact atattcgtca tatgagatga aaatgttgat
    34981 agactctgtt caatactctg ttcatctcct atatctgcaa atacattatc atatacacac
    35041 atactacttc cataatcagc aggtatatga agtccacttt gtgtcataag tgcaaataga
    35101 cctacagttt ttattgtaac agtcttacca cctgtgtttg gacctgttat caccaatgta
    35161 tggaagtctc ttcctaaata aattgtattt gctactacct tctttttatc cagcagtgga
    35221 tgtcttccat tttttatgtt taaatattta tcctcattta aagttggttc tattcctctc
    35281 atctgtatag aaagttttcc ctttgaaaat gcaaagtcca atcttccaag tatctcttga
    35341 ttagagatta aatcttcgct cacttctcca accatagctg aaatctctga taaaattctt
    35401 tctatttcct cttgctctcc tagtttcaac tgcctcaatt cattgttcat ctctactata
    35461 gtcattggct ctataaaaag tgtcgcacca gaagatgact ggtcatgcac tataccagct
    35521 acttgcgacc tatattcaga ttttacaggt actacaaatc tatcacctct tagagaaatt
    35581 attgcatctt gtaagtactt ttgataagta gttgaactta ttattgaatt taattttgac
    35641 ctaatggatt gatttttttg ggctattctt cttctgatat ctctaagtgt acttgaagca
    35701 ttgtcagata tttctacttc actaattata gcattgtata tctggtcttc tatgtccttg
    35761 tacacatata gagaatttga tagagattgt attattggat aattaaaatc ttcttcatca
    35821 ctactagata agctatttct taatcttcta gccactctta aggtatctgc tatcataatc
    35881 agacttcctg ggtcaagaga agcacctata taagctctct ttaccttatc ttctatatca
    35941 tgaatacctt ccaaccctac tgaacctctc tttataataa ttgattgagc ttcactagtt
    36001 tcttctagca tagatttcac ttctacaaaa tcagtatttg gtactaaatt ttctatatat
    36061 tttagaccta aagaagatga ggctttcttc tttaacaaat ctattatttt attgtattct
    36121 agaactctta acgatttctc attcattttc tatattcacc atcctcgata ttttaacttt
    36181 tttatttaat tttaaaaatg tatgttttca agcatttcca ataaaaaatg caagttttat
    36241 ttctttttca tttctaaaat tattatattt tttctctttt agatatattt tacacatatt
    36301 ttgtattata ctatgtatgt agctatctat atattataca taaacatgct ttatttgtaa
    36361 tataatctgt taaaaaatct tctttaatat ttttaaagga gtttatttta gcttataaaa
    36421 aaatagctac ttatatagat aaattaagga ggaacatgag tcatgggaaa cgtattagaa
    36481 ggattaaaac cagaaagtgt ttttaaaaac tttgagaaaa tatctcaaat tcctagaggt
    36541 tctggaaatg aaaaaggcat aagtgatttt ttacttagct ttggtaaaaa tttaggtctt
    36601 gaaactattc aggatgaaag cttaaacata ataataagaa agcctgctac aaaaggatat
    36661 gaaaattgtc caggtgtagt tcttcaagga catatggata tggtttgcga aaaagaaaag
    36721 aatgttgaac atgattttct taaagaccct ataaaattaa gaattgatgg tgacatgata
    36781 tatgctactg gaactactct aggagctgac aatggtatag ctgttgctat gggtatggct
    36841 atattagaag ataatacttt agagcatcct gcactagaag ttttagttac tgttaatgaa
    36901 gaagatggta tgaatggtgc agatgcacta gaccctagct taattaaagg tcaatatatc
    36961 ctaaatatgg actccgagga ggaaggatac ttattagtta gctgtgctgg tggtaaaact
    37021 tgtgttgtta gtttacctgt tgaatacaag gaagttaaag gtgacaaaca aggattatta
    37081 gttgaggtta ctggactatt aggtggacac tctggtatgg aaattgtttt acaaagagca
    37141 aatgctaaca aagcaatagc tagagtatta agtgtattga atgttgatta tgaattagct
    37201 tctgttgatg gtggtactaa gcacaatgct atacctcgtg aagctaaatg tgtaatagct
    37261 gttaataaag ctgatgttga atctgctaaa aaacaaataa atgacatttt aactgcattt
    37321 aaacatgagt ttactacttc tgaccctggc atgacttact cagtagctga aacttctgta
    37381 gacaaagttc ttactaaaga ttgtaaagaa aaagttgttc aaatgtcttg cttaactcct
    37441 catggagttc aatcagtaag tcttgatata gaaggattag ttgaaagttc tactaacttc
    37501 gctataattg aaactaaaga atctactatt gaatttttaa cttctgttag aagttctgtt
    37561 atgtctatta gagatgaaat cgctgataga ataagacttt tggctcaagc tttaggtgct
    37621 aattacgacc ttatagctca atacccagct tgggaattta aaaaaggctc aaaattagaa
    37681 aaaatatgca gtgaaactta tgagaaatta actggtaaag ttcctactgt tatggctcta
    37741 catgctggtc ttgagtgtgg attattactt gataaacttc ctcatgctga agctatctct
    37801 ataggaccag atatgtttga tgttcatact ccaaatgaac atgttagtat cccttctgta
    37861 gctaatgttt gggattatgt tattgaaata ttaaaatcta tgaaccaata ttaaatttaa
    37921 gttttgattc taaatagatt ttaattttaa gtaatctata taaaattaac tctgtaaatt
    37981 aatactactg ttagtataat atttactttc aatattaact tatagaaata aagcctaatg
    38041 atagataata acatgtatca ttaggcttta ttgtaattta aatattatta aactttattc
    38101 tgttttaaaa ttaattctta tactatttta aatctatttc ttccttgtct cttagaatca
    38161 taaagagcat tatctgctat ttgatacagt tcatcatact cttgaccacg ctttgttata
    38221 actaccccca tactaataga taaactttct ccatttggca acttaatgag atgaatatga
    38281 ttgtatacat cattacattt attgataagt tcttccttat ttattatatc atttatataa
    38341 acactaaatt catctccacc taaacgacct actatatcat cttttgcaaa actttcatca
    38401 agtacctttg caacatcaat cagtacttta tctcctacca ggtgaccata agtatcatta
    38461 attgacttaa aataatcaat atctataatc aataaagctc catttttttc agttgataaa
    38521 tttaataaat tttgtgtagt taattttcta atatatgctg cattataaat atttgttaaa
    38581 ctatcccttt gaactttatc caacaatcta ttcttttcct ctttttcaga atcaatatta
    38641 gctattttac caattacata cattggtatt tttctatcat tataaattat ttttgaagta
    38701 attctaatcc aatgaaaagt atcatcaagc atgatagaat acatttcagt agtcccattt
    38761 tcttgtgatt ttattacatc aaaaaacttt ttattatatt ctcttcttat tttatctctt
    38821 tcattttcta tattgccatt ttcactttcc ttatcacttt tatccaaacc ataataagtc
    38881 tcaataccct tttctggcat agaaattatc aatttatctt gcttataatc atactcaaaa
    38941 aagtattcac ttgtcatttc atacaactga gtatgttttt tgagttccaa agatatcttt
    39001 tcgttcatac ttgtacgagt atgtaaacca aatgccataa atccaataat acaaattaat
    39061 aaacttgcta caataaaaat agtctcaatt ggattctgtt gcataatata aagcaacgag
    39121 aaatcttgtc tatatgtagt attttggtag acaattgatt gcattttttc tgatgaaata
    39181 cttataatag ctttattaaa tatattcaat aattcttgtt tatctttttt aattatgcca
    39241 aaacaaatac tctttgcttc ataagtttga ggaactaggc gcacattttt atacttaggt
    39301 tgattcatat agtactgcat agaataacct tctccataag tgtaatctgc atagccttta
    39361 ttaacagctt ctatacactc ttctaaatta tcataccaaa ctatattttc ttcaaactga
    39421 ccataataat caataccttt ggctagagct atacgctttc catttagact attctcattt
    39481 aatttattat taatcatcat agtatattga gtagaaagaa aaggccgaga catagctata
    39541 ttatgttcac gagagtactc ataatcataa atcattcctg ctacaatatc aatttcatgt
    39601 tttttagcca tatcttccaa atcttcttga gattttacag gcacaagttc aaattccaaa
    39661 cctgttttat cacatatatg atttaacaaa tcaattgata tacctcttaa ttctcctgta
    39721 tctttatctg cattttgaaa cggtggtttg tttaaaagta ctcctacttt taatttttct
    39781 gtatctttaa tgtaattagt ttcttcatca gataaaaaca tttgattatt ctctggcgta
    39841 aagtatttct catataaagt agttgaaaaa tatgggtcct tctgttcaat attattaatt
    39901 gctgaattaa gcttttgagt taagtctgta ctgccttttg gagtaatgaa ataaaatggc
    39961 tttgatgaga attttgctac agtacgcaca ccttctattg ggttcatact aacattaaga
    40021 agtacatctg ctttaccact ctttagtact tctaattgct cgtcacttgt tttacaatat
    40081 accaattcag gtgacataag attcatttta caatactcat ctaattcttt aagcctagta
    40141 tcagaatttt ctattacagc aatacgaatt tttttcacat cttgcgaact cattatgtta
    40201 tcaatatctg tattttcata taatgcttgt agtactgtat ttgctactcc ataactgttt
    40261 cccgcataat tatatatttt ttgcattggc tcattgtata acatacctcc cattatatca
    40321 atttcaccat tttctaacat cttcattaat tttgtaatag attcatttat ctctccagga
    40381 acttgaacaa attcataatt ccatccagta tactgtgcaa tttctagcaa atattcatat
    40441 gtatacccaa aatagttacc ttgctcatct atttcagtta aacctttttg aataggataa
    40501 gcaacacgaa tggtacgatt atcattacct atagcattga taccaaaaga aaatatgcaa
    40561 gaagtgaata tagatgtaat tacaataatt aataaaagta atttttttaa attcactaca
    40621 caatcctcca tatagttaag atttacagta taaattactg cataaacttg tagacatgaa
    40681 aaaatagatt agtatataaa aggatatata aatctactta gaaatttaaa tatccttaat
    40741 atatacaata tatttaaatt ataactcatt tatatatcta ttacaacaaa tttaccctgc
    40801 taaataccta ctctatatcc cataatttta caagttgtaa tgaagtttaa gttctatctc
    40861 atttcaaatt tagcagtgtt tctatttaca gttcttttat atttcacatc tggataaccc
    40921 aatataaatg aagtgataac tgcttcgttc tcgctcattc ctaacagttc ttttatcttt
    40981 ggctctacat ttgatgccat aacaaaaaat ccattataac aaattcctaa tccttgagaa
    41041 taggccataa gttccatatt agatgcagcc aatcctccat ctacataagc acttccacct
    41101 agagacatat cacctacaac tatcataagt agtggggcat cataaaataa agaatcattt
    41161 ccgttctctt tatatctttt gtacattttc ttaaatgtat ttttatagat agaacgtaca
    41221 gggtcattgt catcagtatc taatgccaaa ttataaagac cttgtattgc cagttctttc
    41281 acttctttta gcttttcttt tactaatatg tatcttatag gctgtctatt accacctgtt
    41341 ggtgtgtatc taccagcttc cactatgttt tttatttttt cttcttctac ctctatatct
    41401 ttatattgtc ttatacttct tctaaattta ataaaattca ataacttttc gggttctaat
    41461 tcaaaacttt cacgattgta ttctattact tcatttttat caaatccttg catttctatt
    41521 gcatctgttg ggcaaattgc catacagtga ccacagttaa tacagagaat atttttaacc
    41581 tttgctttat catccttaac ttttattgca tttacaagac agtctgattc acacatccca
    41641 cagcctacac atttttctaa atttatgtct atcattccaa attattcctc cttttaaaaa
    41701 atttacttta gtataaaaca aatagttgtc taagtcaatt tttatttttt taacaatata
    41761 ctagccttaa ctacacttta atggagaaaa atatacataa aattagaact taaattagaa
    41821 tttattcaaa ataaaagata aaagaagtaa atgtctaaaa gtgaactttt tagttaatga
    41881 gacattcttt attgtatgaa atcaagtgga tatttatcat ttcaacaata aaaaaggctt
    41941 acctctattt tggatatgtc cttgttaagt agacagacta aaaaaggcta tctttatgca
    42001 ctgagatagc cccttttccc aactactatt gtttatttta atattatatc aataaattta
    42061 atttgctata acctgtaagt tacattttaa tttgatgtaa ctttaaatta catttttaag
    42121 taatatcttt aaattatatt cttaaaatat atcattaaac tacattttaa ttaatctaaa
    42181 aactatatct taattaatct aagaaactta cattataatc ttttagtttc ccattatcat
    42241 atacaatctt tgcactaaag atatttccag tcttagccca atttaagaac aacctgtcac
    42301 cttcccacat atttaaatcg aatattttat cattaccaac ccaaattaaa tttccttctt
    42361 tacaatcatt taaatctttt tcagacaatt caccttcaaa ctcatctgag aaatacaaaa
    42421 acatatacca atcttcttca tctttaaatt ttggaaaagt tatcaaccct ttatatgaca
    42481 atgatttaag agtaagacca gtctcttcct ttacttccct aattacacat tcttctggag
    42541 tctctccttg ctcaaacttt cctccaactc ctacatactt accttcatgt atatcatctt
    42601 tctttttatt tctgtacaac atcaaagtct tgtcatcttt ttctatataa caaatagttg
    42661 taagtttcat gtatctcgcc ttactttctc tttatattct caattaatta ttttcagcac
    42721 tttcaagcac atcacttata ttcttcattg cattaagaga aagttctgca aattcatcaa
    42781 atggaatccc tatatcttct atacttctca ttgcatctct atttacattt gaagcaaatc
    42841 tcgtttcttt cattctttta ataacagact tagtctttac actagtaagt tttttatctg
    42901 gataaactaa agctatagca gttataaacc cagttatagg gtctgctgca tatattgctt
    42961 tttccattaa gctagttctt gtaactccca ttccatcatg atgaccaagt attgctctat
    43021 acatttcttc gtcaccgaag ttttcttttt taagcagttc tactgttgtt gtagcatgtc
    43081 cttcacatat ttctcctggc tttcttccaa ctatatctga atccaaatca tgtaaaagac
    43141 ctgccactgc ccactcttct tctttttctg gctctagtct tttggctaat tctctcataa
    43201 cagcttcaac agcataacaa tgttttctca ttctatcagt ttctaaatac ttaaataaaa
    43261 tttctaaagc ttcttctctc attttcacca atccccctgt tttttcacat atatgatatt
    43321 tttatatatt aatacacata aattcaagtc tttatatata ttcatgtata tttttcatgt
    43381 tatatctatt ctacaccttt atagtagtgt cctgcaactg ttccaatttc atctaatttc
    43441 ttatacaaat ctgtagcctt ttttccaagt ttataattat tactcaatac ctcaatgtga
    43501 gcttcaataa cctttttaac catctcacta tcttcaactg taaaatctat cctaaataca
    43561 tctattccaa tttcctctaa ctcatataga ttgtccaaca tacaagtaac cttcgaattg
    43621 taaattgtac ttctacagaa tatatcttgt gttatcctat aacttgcatc cgtaaagtct
    43681 cttaaagcat aactactttc cttacattta gcaactctct tgtccttttt acaatctcta
    43741 acaactactc ccataggaca gtattctgta accatcatag gagcatatcc atatattact
    43801 gcttcaattt ctacatctgt atattttaaa gtttgtttaa tttcatttaa gtttagttct
    43861 tgtgacaaac aaactgtact tgctccctct tctttgaagt ggtttatact ttcactattg
    43921 aatgcattta agtagcaatc tatatttaag tcttttttct taaagtattc catagagccc
    43981 cagttaccaa tttgaacctt attaattcct tttatattat ccaatatctc aaattgcttg
    44041 tactctttat ttctaacaat ccttggtgct gaatagatta attttttgtc agtgactgct
    44101 gtattatagt ggttcttatt caaagtatct attttacttg tatttgacaa agtatctatg
    44161 ttatttgtat ttgaacccat tagttcttta ggaataccta aagacgaaga agtatctaaa
    44221 tccatagaaa tacttgaatc tatagaaata cttgaatcta tagaaatact tgaatctata
    44281 gaaatacttg aggccatttg taaagctttt gataatgtat ttatatcttc ataatagatt
    44341 aaatctacat tataatttaa tactgcttct aattgctcca agttcttaac tttaactcta
    44401 atcttaggaa ctgtatcaag ttttttctgt ttatttactc tatttggttg gtattttaat
    44461 ctattcttct taaattttct atcttttatc tttattcttt cttcatctaa aagctcaata
    44521 caatcccttc tcatttgatt taacacactt ataggcatac ttacaccttc atccaggtca
    44581 atttctatct cttttaactt atatggtgta tttccaagct tttgaatttg tgtttctatt
    44641 ttttctttac ttaaagccac ctttatagct ttttcaacta ttttgtctcc ttctaccacc
    44701 gatttatttc cacaaaaatc acttataaaa agctctggct ttttacctag tttaatactc
    44761 acttttgcac gtatattagt ttttatgaac tctttatctt gctgaaatgt agcttgtact
    44821 ctattcatta attcgctgtc agaagtctta tatataagct gatttctctt tgcttctcca
    44881 acaaaatcta attctatcaa atccccttta tgtgctattg tagttatctc tccatccttt
    44941 attattcttc caatagtacc tccacctaag ttaattccat cacctttctt aagcgtattt
    45001 tctagcatta ctctaagtct tttgttcttt ctattataat ctaaaacttt tccaatatat
    45061 agcccttgat tattaggtct attagagttc attatatcct taccaacttc acctaatata
    45121 tatccttttg taaactttct attaaatatg gtatacaaat tatttattat ttcctcagaa
    45181 atacttattt ttttcttatc tacaaattca ttaatcgctt ctctatatcc tgaaaccaca
    45241 gtagctacat actctggttt tttcattctc ccttcaattt ttaaagataa tacacctgtt
    45301 tcaattattt tatccaaatc ttctatagta cttaaatctc taggactcaa caaataatct
    45361 ccattacttt ttactacttc tcctgtattt atatctatca actcatactt ttgtctacat
    45421 ggctgtgcac acctacctct atttccagac ctattgccta tcatactact cataaggcat
    45481 tgacccgagt aacatacaca taaagctcca tgtacaaaaa cttctatatc tacagttgta
    45541 ttttcacaaa tccattttat ctcatcaaca tttaattctc ttgctaaaac aactctatca
    45601 aaccctacac tctgaaggta ttttacatct tctaaggaat gtgctaccat ttgagtgctt
    45661 gcatgtagtt caaagtcagg taatagtttt tttataagtc ttgccattcc tatatcctgt
    45721 actattaaag catcaatatc tatatcgtat aaaaatttta catactctac aaaatcttct
    45781 atttcatact gttttatcaa tgtatttaca gtaacaaaga cttgcactcc ccttatatga
    45841 gagtatttaa cagcctcaat cagctcattt ctatcaaagt tatttgcaga tgctctagca
    45901 ctaaagtctt taccacctaa atacacagca tttgctccgt tttgaactgc tgcttttaat
    45961 gaatcaaaag agcctactgg tgcaagtaat tctatttttt tcatattttt ctcctctatt
    46021 tatacttgtt aggttaatat aattatatct ataacttaaa tatttgtatt aaatttatat
    46081 atttcttact atattttaaa ttcttcaatt aatttatata ttagttattt atatttggtc
    46141 catttgagtt aaca
//
LOCUS       DAMJWO010000023        45977 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.024, whole genome shotgun sequence.
ACCESSION   DAMJWO010000023 DAMJWO010000000
VERSION     DAMJWO010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45977
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.024"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(72..275)
                     /locus_tag="PC366_001332"
                     /pseudo
     CDS             complement(72..275)
                     /locus_tag="PC366_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
     gene            complement(275..604)
                     /locus_tag="PC366_001333"
     CDS             complement(275..604)
                     /locus_tag="PC366_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HDF2576865.1"
                     /translation="MPQIKIRGINENDICKISKKMINDLVEAVKCPRDYFEIECIKSV
                     AIRDGKIADVYPFVEVAWFDRGQEVQDIVARIITDSIRNNLDVESMDLAFTVFEKEKY
                     YENGEHF"
     gene            934..1860
                     /gene="fba"
                     /locus_tag="PC366_001334"
     CDS             934..1860
                     /gene="fba"
                     /locus_tag="PC366_001334"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HDF2576866.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSANSIN"
     gene            complement(1995..3626)
                     /locus_tag="PC366_001335"
     CDS             complement(1995..3626)
                     /locus_tag="PC366_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2576867.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     RNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNENNIVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLTGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNVIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(4109..5146)
                     /locus_tag="PC366_001336"
     CDS             complement(4109..5146)
                     /locus_tag="PC366_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDF2576868.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            complement(5165..5950)
                     /locus_tag="PC366_001337"
     CDS             complement(5165..5950)
                     /locus_tag="PC366_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012703997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HDF2576869.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEHDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKVGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            complement(5983..7116)
                     /locus_tag="PC366_001338"
     CDS             complement(5983..7116)
                     /locus_tag="PC366_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HDF2576870.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAGGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            complement(7164..8291)
                     /gene="hadC"
                     /locus_tag="PC366_001339"
     CDS             complement(7164..8291)
                     /gene="hadC"
                     /locus_tag="PC366_001339"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HDF2576871.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKNETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTELVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            complement(8291..9517)
                     /gene="hadB"
                     /locus_tag="PC366_001340"
     CDS             complement(8291..9517)
                     /gene="hadB"
                     /locus_tag="PC366_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HDF2576872.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            complement(9532..10332)
                     /gene="hadI"
                     /locus_tag="PC366_001341"
     CDS             complement(9532..10332)
                     /gene="hadI"
                     /locus_tag="PC366_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HDF2576873.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            complement(10371..11570)
                     /gene="hadA"
                     /locus_tag="PC366_001342"
     CDS             complement(10371..11570)
                     /gene="hadA"
                     /locus_tag="PC366_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HDF2576874.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKAQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            12247..13245
                     /locus_tag="PC366_001343"
     CDS             12247..13245
                     /locus_tag="PC366_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HDF2576875.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENVVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            13607..14134
                     /locus_tag="PC366_001344"
     CDS             13607..14134
                     /locus_tag="PC366_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HDF2576876.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASVVAGIVGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            14161..14757
                     /locus_tag="PC366_001345"
     CDS             14161..14757
                     /locus_tag="PC366_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HDF2576877.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEVAKFIKEKSSIKIRINTNG
                     LSDLIHNKKTAILLKDVIDTVSISLNAPNKEAYNRVTQPKFGEKSFDYMLGFARDCKK
                     YIKEVAFSVVDEISPEEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(14822..16405)
                     /gene="asnB"
                     /locus_tag="PC366_001346"
     CDS             complement(14822..16405)
                     /gene="asnB"
                     /locus_tag="PC366_001346"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDF2576878.1"
                     /translation="MINLEEKYLTRKDTYMIKILEYNGHIRNWKVLCEELGIDSSLCR
                     DERERAILVEAYKTWGYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYETEN
                     GKLLYGSSIRKIMEQPGFVKELNEDMLQIYMSFTYVAGENTFFRGVKKLMPGHYLVYQ
                     NKTVCIGRYWKPEFHPDHSKSIEEWTDEIHTTLQKIMPEVKSENETAELFLSGGVDSS
                     YILAMSDIEKTGSCGYEEERFDESKLAQQTANILGCKNSRYIITPEEYFASVPYVMYH
                     MEQPTGDASAIVFAIGCKAAAENTNICYSGEGADEFFGGYNIYHKAECYGENLKTFYI
                     GNTNIMNEGEKRKILKKYNPDVLPIEVVKGIYEETEELDTLTNMSNVDIQIWLEGDIY
                     FNIDKMSTAVGLEVRMPLTDTRIFDIASRIPSEYKVKGKENKIAFRTAASKTLPEEIA
                     FRNKLGFIVPIRIWMADDQYNKDIRDKFNSEIADKFFNIDEINEIFNDYISGNSDNWR
                     KIWMIYTFLVWYEIYFVKC"
     gene            complement(16971..17807)
                     /locus_tag="PC366_001347"
     CDS             complement(16971..17807)
                     /locus_tag="PC366_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2576879.1"
                     /translation="MNYIIKKVLNSSVVLVHDAKYNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKKFLELMDDIPVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSGDDLLFNQMKRSNPKEMLIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
     gene            complement(17831..19297)
                     /locus_tag="PC366_001348"
     CDS             complement(17831..19297)
                     /locus_tag="PC366_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDF2576880.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADV
                     KDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVI
                     FQAMHHQFVASALATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLATQQKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIAKEEHDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIENNSIDFK"
     gene            complement(19300..21162)
                     /locus_tag="PC366_001349"
     CDS             complement(19300..21162)
                     /locus_tag="PC366_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2576881.1"
                     /translation="MNYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVNGAQFQVVIGNSVVDVYDEILKVCPLDTNDSTVKTEEKINLGTRFIE
                     FIINIFQPLIFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLVAISDATFYFLPLMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPNIAYNAQVFPAILCVS
                     FLATMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAFLPFMVATGMHKALIPYSINTIGKLGYEALYMTSSLAHNISESGAC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAMLGVVFSSAISGTFLG
                     LFAVKGFVIVGPGLASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNTV
                     ESSIGDVVEEELEEEKEVNILVTPVEGKVIDLSKVNDELFASKTLGDGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNNNGADYAYKVLNQSYGNVKKGSILFDVKGGI"
     gene            complement(21409..22272)
                     /locus_tag="PC366_001350"
     CDS             complement(21409..22272)
                     /locus_tag="PC366_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDF2576882.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDRVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFLKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKIICEIFSNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            complement(22327..23259)
                     /locus_tag="PC366_001351"
     CDS             complement(22327..23259)
                     /locus_tag="PC366_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HDF2576883.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKDVISHNYKYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENLLDEFTTLTEATHWSGTTYGEES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEPLKTLLCVGGVHFEK
                     SFSDIIKNKEYNISIGHVLPNQWIVSGMYDDESGFEKLEKCINSIEGGIDCIVFHDKL
                     KGTYKEQCRKLGEKLNVPVFKHKILKNPKDLPIW"
     gene            complement(23345..23896)
                     /locus_tag="PC366_001352"
     CDS             complement(23345..23896)
                     /locus_tag="PC366_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2576884.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDIDHFIEDNGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYIVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYI"
     gene            complement(24125..24616)
                     /locus_tag="PC366_001353"
     CDS             complement(24125..24616)
                     /locus_tag="PC366_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576885.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMDDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            complement(24644..25204)
                     /locus_tag="PC366_001354"
     CDS             complement(24644..25204)
                     /locus_tag="PC366_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDF2576886.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVSNWIDIEKIIKQGI"
     gene            complement(25356..26513)
                     /locus_tag="PC366_001355"
     CDS             complement(25356..26513)
                     /locus_tag="PC366_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF2576887.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRHFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVVIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDSILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASKNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKTKTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            complement(26550..27491)
                     /locus_tag="PC366_001356"
     CDS             complement(26550..27491)
                     /locus_tag="PC366_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576888.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLKQDNKKNEEISNNKNL
                     NNKQDRNIQNKESNEEGSNDIKEKNNSDSNVSVNNKSEKQEDNTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNSETNNIN"
     gene            complement(27578..28270)
                     /locus_tag="PC366_001357"
     CDS             complement(27578..28270)
                     /locus_tag="PC366_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2576889.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVKEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYEDMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            complement(28380..29192)
                     /locus_tag="PC366_001358"
     CDS             complement(28380..29192)
                     /locus_tag="PC366_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HDF2576890.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            complement(29243..30154)
                     /locus_tag="PC366_001359"
     CDS             complement(29243..30154)
                     /locus_tag="PC366_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2576891.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYVFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVCIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKSIEVGKIELNNEMFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQINSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLYQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            complement(30213..30944)
                     /locus_tag="PC366_001360"
     CDS             complement(30213..30944)
                     /locus_tag="PC366_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HDF2576892.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFDKLNDVYKSLPVGNCSGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTRKNPCPFKDTNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMILDSNIYSSGNIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEYKIRKRTIDRIKRIVLV"
     gene            31033..31284
                     /locus_tag="PC366_001361"
     CDS             31033..31284
                     /locus_tag="PC366_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576893.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGTKFINKKR"
     gene            31517..31936
                     /locus_tag="PC366_001362"
     CDS             31517..31936
                     /locus_tag="PC366_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576894.1"
                     /translation="MQIYFRVKAVGKRKPMLELTPFDVSDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIINFLTNEEIESQADIGKVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSPINLKSGDIFTFIRLTLLAGRMF"
     gene            31961..37018
                     /locus_tag="PC366_001363"
     CDS             31961..37018
                     /locus_tag="PC366_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HDF2576895.1"
                     /translation="MLERTRVEKNPKIIENFKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISNYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQKVTSALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMLSKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEIYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETNFDLSNTPIDKDFDARKEQFESLKHTLEILNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNRETVLSLLRKLELTDVELDKITNLLSLKTSSIRQTVIKILLEQDDSNLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNSDRQELYNKLILLIEDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNPENKVQIPEQFDFKDDSNSSSKLNKIISNISLSTSEDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLDLDYKLILDILFYSISTCGYNETEKSWF
                     SSIYSNVLDSKKQNKIYTKLEKFKFNGLTRKLLRVLLNEFDHKEIFNYCLEIYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTEEQVNREMISGYNASNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSHLANNIQYFEGIDYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPRSFIDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACTIALENLA
                     RSAGFGDVNRMMWALETEKLNEVAHLFKPKDIDGTSIWIDVDESGKASTKVQKGNKSL
                     KSIPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGETYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQLVQPFKQVFREYYRINSDEISEKTISRRYAGHQIQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PILFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKINNINFEGSHV
                     LITGNLGEYSVHMGSGIVHKKGMGALNILPVHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDNKIKDPSILSNL"
     gene            complement(37178..37915)
                     /locus_tag="PC366_001364"
     CDS             complement(37178..37915)
                     /locus_tag="PC366_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2576896.1"
                     /translation="MIKVLICDDDKIVRDDIANIVKESGYVDYVKKVKDGIEAIEFIK
                     SEKIDLLIIDIDMPYKNGIDSAKEILSIDKDIHIVFVTGFADYSLESFKVHPIDFIVK
                     PFKKEKILDSINIAIDHINSHKIAKNNFIEDTLFVYKIRKQIHMINFDDIVMFEKNSR
                     AINLYTRDEDTIKFYENFDDLKKRLPPNFFMTHRQYIVNLRLIHKVIPINKSSLEIKF
                     INFQESATLNKSLEKDFLYRFYRVKRF"
     gene            complement(37934..38869)
                     /locus_tag="PC366_001365"
     CDS             complement(37934..38869)
                     /locus_tag="PC366_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2576897.1"
                     /translation="MENNFIFPIVILTLFIFSNLIMNKYRFYKELDILKRGILTFFVS
                     CFVWILFMEGIEYIQLSLGYNFLLEGVLNIILFLILIILSFYIGFKFIRLLDNNNKQE
                     YKLQKLDSKINHKDNIIVKLRSQKHDYLKHLQVVYSLLNTGLAEDAKEYITNISNSFK
                     SKNSRYGKVSYLDAIASLKYEECLEKNISFDVYIQDFMDNLEIEPNDMSSVLLNIIDN
                     AIESLSAIQKEKKYIRLHAYEDEFQYIIAIKNNGPKIHNVESIFLDGFSTKEGQDRGF
                     GLYLVKNILDKYDYSILVNSDDFLTEFVILIPKYY"
     gene            39077..41662
                     /locus_tag="PC366_001366"
     CDS             39077..41662
                     /locus_tag="PC366_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2576898.1"
                     /translation="MKDNLKIALRYIISYKARSLAIALSIILATSLIVGIGTLSRSAQ
                     QAEVDKLKRETGSDHVYFKDINKNQLEYIKSRKDIKNLGITSHYGYTDPNERLAINLE
                     YANKNYLTNQSKLIKGHLPKASNEVVVEKWILNSLGLKPEINQNITFKLYQKEKPETF
                     KVVGILEDRPIEKNKGTCEIFLNLNESKLDKFSYAYIEFNNGIDINTSIDNIVKNTML
                     DENSVGKNKMLIESTRENGTLDNSSKYTAITMSLFSGIVIYSIYVISIYQRIQEYGIL
                     RAIGSTNFKIFKFMFYELFILALIAIPIGICTGIGGAQIFNRTAGNIQFEGNVTVTPF
                     VIPDKIILLSIGSIILTILIISFFTYLKIRRISPIDSIRKTFGTDKNINKVNSLISKL
                     TLNISVTKSISAKNIFRNKKGFIIIILSMSLGGIMIIKENYKYSFSDIQNKNGQEETY
                     MNADFILTNFFLKLNQSNKADSFKDIKGLNDNQIDKIKNINGIDKVKTASILDTRIEV
                     DKLNGLDYYNIINSTPYYKDFPLFIKNKNTGKYTMKQKLRGYNDEMINSLEKYLVSGS
                     INLERMKKENLAILYVPQVSKTNKYKLSYTPGTETPAVDIKVGDTIKVKYPKGEIDQD
                     LYIKLKDNYEYLEYEFKVGAIVSYPFADNYLYSGDQGIDVITSNDYLKKLTGVDKYNV
                     VYVDINKNANVKKINTLLGEIGSESPGTTTANMLMEKENFDKMTARALTYAYGIVAVM
                     FIISVFNIINNISYNLTSRTSEFGMLRAIGISERGFKNMILYEGILYGILSSVITIVV
                     GLIIQFRMYYTYNFVSYGLGFSIDYKIYILVVLANIIVGILATYIPLRKINKISIVEA
                     INITE"
     gene            41674..42345
                     /locus_tag="PC366_001367"
     CDS             41674..42345
                     /locus_tag="PC366_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2576899.1"
                     /translation="MPILEILNLGKIYGKKETAVHALKDANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSSGTIKVDGKDICCLSDKKLAKYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKVDEEYIEDIINLLGLSERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKADRIISIIDGE
                     LKLTL"
     gene            42372..42713
                     /locus_tag="PC366_001368"
     CDS             42372..42713
                     /locus_tag="PC366_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576900.1"
                     /translation="MLLILDNLNLNLDFDYRIIREENDDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRINKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIINIKNQN
                     EKVILNKSIKK"
     gene            complement(43073..45715)
                     /gene="adhE"
                     /locus_tag="PC366_001369"
                     /gene_synonym="adhC"
     CDS             complement(43073..45715)
                     /gene="adhE"
                     /locus_tag="PC366_001369"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDF2576901.1"
                     /translation="MEKKEKVVEKSNVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNARIVGQPAHVIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPDRVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTAASGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGNTDQEKVDNLIKAIDELKARVGLPKTIKEAGVEESKFLETLDVMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
BASE COUNT        15422 a         7654 c         5621 g        17280 t
ORIGIN      
        1 gtttccctat atgctgacta ttttagctac taactcatga ctaaagtcac gagtgtacgt
       61 agctattttt taatcaaata tatatattct ctatatataa cttcttctcc attaaataat
      121 atctcatcat tttcagtgtc tacttgagtt cctggatttg aaacttcact tccatttact
      181 actacagacc cttgtttaca atacttcttt atttcacttc tacttccata acctaaattt
      241 gaaagaattt tatctatacg ttgcttttta gccattaaaa atgctctcca ttctcataat
      301 atttttcttt ttcaaatact gtaaatgcta aatccatact ttctacatct aaattatttc
      361 ttatactatc agttattatt cttgctacta tatcttgtac ttcttgtcct ctatcaaacc
      421 aagctacttc aacaaaagga tatacatctg ctattttacc atctcttatt gcaactgact
      481 ttatacattc tatttcaaag tagtctcttg gacattttac agcttcaact aaatcattta
      541 tcattttttt acttatttta catatatcat tttcattaat tcctcttatt tttatctgtg
      601 gcatagttta tctcctttat tttaaatttt tagtgaatta tcatccactt aattcccttc
      661 gataacgttt gaagtggtaa cttcttggtc aagacaacta ttgttatcag tatctccaaa
      721 ctaataaggt agttcctacc cttatagtta gcattatata gctaattttc ctaaattatt
      781 tatattcttt attattttat ttaatcctat tgtcttctat ttaacattat acttgtaatt
      841 tatagttatt acaatttact atatactttt tttgatttaa cgttataata taagtgatgg
      901 gtaaatttta aaagttaata ggaggagttt aaaatggcat taattactac aaaagaaatg
      961 tttaaaaaag cttacgaagg tggatttgct ataggtgcat ttaacataag tgacttagaa
     1021 caattacaag gtgttttaaa agctgctaaa gctaaaaatt cttatgttat gatacaagct
     1081 tctatgtcag ctgttaaata tgctggacct catacattag ttgaaatggt taaggctgct
     1141 tctgatgaaa taggtgtaga tgtagctctt cacttagacc atggtccaaa tatggatgct
     1201 attaaaactt gtattgatgc tggtttctct tcagttatga tagatggttc tcattttgac
     1261 tttgaagaaa atgttagaat aactaaagaa gctgttgaat atgcacactc taaaggtgtt
     1321 gttgttgaag cagaacttgg tgttctagct ggaacagaag atgatgttac ttctgatgtt
     1381 cacaagtata ctcaaccagc tgaggcagtt gagttcgttg aaagaacagg tgttgattca
     1441 ttagcaatag ctattggaac ttctcatggt gctttcaaat tcaaaggaga agctaaatta
     1501 agatttgata tactagaaga aatccaaagc aaattaccag gtttcccaat agttcttcat
     1561 ggtgcatctg ctgttgacca aaacgctgtt gctacatgta atgaatttgg tggaaatata
     1621 gctggtgcta aaggtgtacc tgtagatatg ttaagaaaag catcttctat ggctgtttgt
     1681 aaaataaaca tggatactga cttaagacta gctatgactg ctgctatcag aaaattctta
     1741 gctgaaaatc caaaagaatt tgacccaaga aaatacattg gtgctggtag agatgctata
     1801 caagctgtag ttgaaagcaa gatagatgat gttttaggtt ctgctaactc tataaactaa
     1861 tataactttt aaatatttat aaaagaaaag agatgactta aagtaattaa atttattttt
     1921 aagccatctc ttttaagttg tatcaattat gtatcttata atattttaat tatattgtct
     1981 ttttaaactg acagctaaac gtgaatatgt ccactcttta tctttctatg gatggtagaa
     2041 ggatatatac ctataacttc agcagccttt gttattgaac catacttatt tatagcctta
     2101 cttatcatta tttggtccac tattttatat gcatcattaa gattcataat tccatttacc
     2161 actattggtg ataaatcatc tgtttcatta tcaatcatat ctaaatttat cagcatgtta
     2221 aattcatctt ctccaattac atttttagct gataatacta caaatctttc aatgatgttt
     2281 tttaattctc ttatgtttcc tggccaagaa tattcttcta ataactcaat aactttaggt
     2341 gaaacttcta cttctctatt gtacttttca ttgtaaagtt ttaagaaata atttactaat
     2401 ggtactatat cctcttttct ttctctaaga ggaggtattt ttactggaat aacacttaat
     2461 ctatagtaca aatcttgtct aaatttaagg ttatttctaa ggtcttcatg agaaatatta
     2521 gtagcactta tatatctaac atctattttt ataggcttac taccacctat tctagtaata
     2581 gtattttctt gtataaccct aagtaatttt ttttgcatct gcattggtaa ctcacctatc
     2641 tcatccaaga aaatagttcc accattcgcc tcttcaaaaa gtcccttttt accttttttc
     2701 ttagctccag taaaagaacc ttcttcatat ccaaaaaact ctgactctaa taattcattt
     2761 ggtatagctc cacagtttat agctataaaa ggtttgtctc tccttgaact atacttatat
     2821 attgttcttg ctattatttc ttttcctaca cctgattctc catttataaa tatagaagaa
     2881 tctgaggctg cagctctctt aacaactttt tttatattgt ccataatctt actttgactt
     2941 atatactctg tgtcttctga tatatcacta tattttatct gagattcaag cttaataacc
     3001 cttgaaatat ctctccctgt tagtactcct cctgtaagct ttcccttaga atcccatctt
     3061 ggaactgccg tatatgcaat aagcttccca tctgggtaaa cgatatttct ataaatcttt
     3121 ttcttcactt taagcatgtt taatattatt ggttcttcaa ctaatccttg tctcacaagg
     3181 tctgttatat ttctaccaag tacctcagtt cttttaaaag gtaatatctc atcactgaca
     3241 gtgttcatct tttcaattac cccatctttg ttaaacacaa caacaacttc atctatatgc
     3301 tctattatat cttcaattac tttatcagat attagagact tctcaaataa ataaactata
     3361 ttattttcat tattattatc tttcatattg tatatatgtg cagtcatcct taactctctg
     3421 aaagctattt tctttttact atctgtcagt atttctgttt tgtcaaaatt tgaatctaat
     3481 tcatttatat ttctaggctt ttttatatct agaaaactaa aaatactatc tattagatga
     3541 ttacagtata ttatttcgcc tgattcttta cataaaatgg ctggattttc tacatgttct
     3601 ataagcccta ttaaattatt atccattaat attcgcacct ttcattaagt aatttattga
     3661 actacataca aaatttattg tttgcttaca ataaatacca tcagcacata taatcaactc
     3721 cttataatat tcgtcttttc aagtagttta tttcattaaa acgtaactaa gatataattt
     3781 taatgattat agtttgttaa aaatttcatt ttgcttttaa ttgtatttta tcacatattt
     3841 agtaattatt tgtctattta atacaattta attaaattta agatttattt aaaaaaacaa
     3901 agataatcct tacagaatat aactcacaat ttgtaagcaa tatacatata aggattatcc
     3961 agattatctt gtattataaa attttattca aacagacttt ttaataactg acaaatacac
     4021 actagcaata acttatcaaa gggttaataa ttatgttact aactaataag acttattcaa
     4081 tcagtaatat ttatatagtt tgtatctatt aagcttttat agcttctaat aaatcatcaa
     4141 cgctatctaa tttttctata agcattggaa ctatttcatg taagtctcca actactccat
     4201 agtcagcgat ttctaaaatt ggagctgctg ggtttttgtt tatagcaatt atgaaatctg
     4261 atgattgcat acctgctaaa tgttgtattg ctcctgatat accacaagct atatataggt
     4321 ttggtttaac agtagttcct gtttgaccta cttggtgaga atggtctatc catccagcat
     4381 caacagccgc acgagaagaa ccaactactc cacctaattt gtcagctaat ttcttaagca
     4441 tttcaaatcc ttctggtcca cctaatccta aaccacctga tactataaca tttgcatctg
     4501 taagagatac taaatctttc ttagttttaa ctgtttctaa aacagtagtt cttatatcat
     4561 cttgagttat tttgtagtct aatgctataa cttcaccagt tcttgtttcg tctttttcag
     4621 ctttatccat aacaccaggt ctaactgtag acatttgagg tctatggttt ggacaaatga
     4681 ttgtagccat tatgtttcca ccaaatgctg gacgagtttg ttttattttc ttatcttctg
     4741 ggtctatttc taacttagta cagtcagctg ttaatccagt tccaactctt gaagctattc
     4801 taggtgctaa gtctctacct atatgagttg ctccgaaaag cattatttct ggttttattt
     4861 catctattgc atcttttatt acttttgtat atgcatcagt tgtatatttt tctaaaagag
     4921 catcatctgc aacataaact ttgtcagctc caaaagtgat taattcttta gctaatccat
     4981 caacatcttt tcctaataat attgcacaaa gttctgcatc tacttcttta gctaattttc
     5041 ttccttctcc taataattct ataactactg gagctatttt tccttctctt tgttctgcaa
     5101 atatccatac gtttttataa gaacttaaat cttttatatc attcatagtt tgtactcctc
     5161 caacttatat aatgtgcttt tgttttagac cgattattat tttactagct atttcatcag
     5221 ctttaccttc taagatttct ccttttcctc ttggttcagg agtaaatgat ctaaatactt
     5281 tagttggtga tgcttttaaa ccaacttctt ctttatttac atctaaatca tcaattgtcc
     5341 aaacttttac atcatgttta tatgctttta ctattttatc aacagacatg tatctaggtg
     5401 tatttaactc ttttactgct gttaaaagta caggtgtact tacttttatt aattcgtatc
     5461 catcttctaa ttgtctttga actattatat cttttccttc tattttgaaa tcttgtacat
     5521 atgtaacttg aggaatgtct aatttctctg caatttgtgg tccaacttgt gcagtatctc
     5581 catctattgc ttgtcttcct gcaaatatta tgtcatagtc acctacttta gatattcccg
     5641 ctgcaatagt atttgatgta gcccaagtat cagctcctcc aaatgctcta tcacttaata
     5701 atattgcatc atcagcaccc atagctaaac actctcttag cataaagtct gcttgaggag
     5761 gtcccattgt tataactgtt atagttacat catcatgctc atctttaatt tttaaagctt
     5821 cctctaatgc atttgcatca tctgggttta atatacttgg aactccatct cttataagag
     5881 tacctgtttc tttatttatt cttacttcgt tagtatctgg aacttgtttt acgcaaacta
     5941 atattttcaa agtctatacc tccaatttca ttagattatt tattatttta atacgtttga
     6001 tgaaattacc attttttgaa cttctgatgt tccttcgtat attgatacga ttctagcatc
     6061 tctgtacatt ctttcgattt cataatcttt tataaatcca tatccaccgt gaagttgtaa
     6121 tgctttataa gcaacttcat ttgcaatttc tgatgcatag tatttagcca tagcagattc
     6181 ttgagcaact ctcattcctg catctctctt ttgtgctgca tcataaacta atcctctagc
     6241 tgcacaaact tttgtttcca tgtcagctat agtaaattga gtattttgga atttagctat
     6301 aggcttacca aattgaactc tttgttttgt atatttaaca gcttcatcta aagcaccttg
     6361 agctattcct agagctaagg cagcaacacc tattctacca acttctagag tacccattgc
     6421 tatcttaaat ccttgacctt cttttccaag taagttttct tttggaactt taacgttttc
     6481 aaatattaag tcagaagttt cagttcctct tatacccatc ttatcttcat gagctcctgt
     6541 tgagaaacca tcccatttac tttctactat aaacgctgat gttcctctaa gtcctttact
     6601 tctatctgta actgctatta ctatagctac atcacagaat ggtccattag ttatgaaagt
     6661 ttttctacca tttaatatat agtggtctcc aactaattct gctgttgttt gttgtccacc
     6721 tgcatcagaa ccagctcctg gctcagttaa cccaaatgct cctattaatt cacctgttgc
     6781 tatacctttt aagtattttt gtttttgctc ttcagtacca ttgtaaagta ttggtaatga
     6841 agcaagagaa gaaccagctg taacaaaagt agctgttgaa gcacatcttc tagctatttc
     6901 ttccattact atagcgtaag aaacatatcc tgctccccca ccaccatatt cttctgggat
     6961 attactgctt ataaattttg catcagctaa ttttttgatt aattccttag gcattacacc
     7021 tgttttatcc atttctgctg gtaaagtatc taattcttta ctaacaaaat ctcttactgc
     7081 ttttcttaaa agttcttgtt ctttgttata taacatagct tcctccaatt ttcatatttt
     7141 atagtaaatt tattttaatg aacttacgct aaactcatca tctcagcaaa agtttgaata
     7201 cgagttctgg cttgttcatt attctgagtt tgttggtcga tttcaacata taaagtaggt
     7261 attccactat cttctatatc ttttctaact aaaggataat cgtattcttc tgggtcacag
     7321 aatttcatca tacagaagat aacaccatct atatctttct ttttaacttc atctactata
     7381 agtgacccac gttttttctt agggtcataa gctaatgaac atccttctat gtttgaccat
     7441 tgtcttgcta atctctctaa cgcatcatca cctgctggta catctgttct gaattgtctt
     7501 gtttcttgtg ctaagtcgtc agctacaact gatatattgt tgtcttctaa aatgtctaat
     7561 atatctttag aatcagctaa tatacctgtt aataaaactt tttttccaga acagacttct
     7621 tctggcatag catttaattt tgctattaaa tctttcacta gctcagtatg ttcttctttt
     7681 ctcataaaga acccactttt aattactaag cttcttattg atggttttat agtattagaa
     7741 tgtttataag ctacttcaac aaagtctctc atagtttttc tatgttcatt gtaaacttct
     7801 atactttcat gaatttttgc ttcttctatt tcatatccac aaatttcttc aagttctctt
     7861 tttacacctt tgtactcact gattaagtat tttacaccag cttcaagttt tctattttgt
     7921 gggtgtacta atgatatata ttttatatga ggtactgctg atttccagtt ttgtcctaaa
     7981 caaattagtg tatcacacat acctggtata ataactccag ataattcatc ataagcacct
     8041 tttaatccat attctaaaca tgattgcatt attgaacatg caaatgcagg gaaatattgt
     8101 ttagctaaat ctaattctgt ttgtcctccc catataccaa ctggaagcat tccagctgca
     8161 tgtataattt cttctgggca ataaactggg aaacaaccta tagctttttt accagtttca
     8221 tttttatatt tttttacagc cgcatttgga ttttcaacta cttctttcat tttagataaa
     8281 atagcttcca ttatatctca cctctattaa gtttttttct ttcttccatt acttcaacta
     8341 aaccttgaat tcttgtttca aattgagcat tagtgaaagc tctagggtct gcttggtcac
     8401 catcaaatcc agcatatggt aatccagttt cttcagctgc tcttctttgc atttcatatt
     8461 gtattaaact cataagttta cagcttctgt tcatatgata gaatgctcca tcacatttac
     8521 cctctactaa agaatcaact ctatattttg tcatacggtc taggtttaca ttgttaaaca
     8581 tagtactata tgctactgcc attccatcta aatcattaac ttcatattgt aatgcccaag
     8641 catgtgggta aacactacct gtcatgttaa ctccaaattt agctaatgtt ttcatcttgt
     8701 atcctatata tggccaacaa ggtatacctt ccatcattat tctgtatttt tcttcccctc
     8761 tgaaagaaga tttaccagtt ttcatgttgt cttctaattc ttctataagt aacttaaatg
     8821 cttctgtagt ttctttttta cctctagcac aaactattac agccatgtaa gtaaataagt
     8881 caaatccatt cattggagaa ggagaagaat ctgctggtaa actcatagaa tacttccata
     8941 gtcttccgtt ttcagctgat attttcatta cttcttcaaa cttcttaggg tcaaatttct
     9001 ttcctgatat aatttctagt tgttttatag cttcttcaaa ttgagcttta atataatcta
     9061 ttcttgattg agtaacttcg tcttcattat tgaaagttgt atcaatcatt attaaaggta
     9121 tatctaattc tcttgaaata ttttcatacc attttataac ttgattacat atattgttac
     9181 agcaaagtag gaaatctgga gctggcatat ccaaagcttc acatccacca ttttctaaaa
     9241 gaccaaaatt tgttcttgca tatgcacata ggtcaataga atatccttta gattcagcta
     9301 tttcacataa ttctaaagaa ccttttttag ctgctactcc agctgcttgg ttttctggat
     9361 ataatacgtt taagtcaaat acttctgcta actcttgagg aaatactgat gttgaccaac
     9421 ctacaggtct tccttcttct ttagctttaa atgcatttgc atattgttca gctaataaat
     9481 cattaattac tactctagct tctttttttt cagacatttt catccctctt tttatatatt
     9541 tttcacttct ttttgtgatt cttttgcttc atcaaaagca tataacgctg ctcctaaagc
     9601 accagttaat tgaggtatat caggtacaat aatttctgtg ttgatttctc ttgccatagc
     9661 tcttacaata ccactatttc tagcaactcc accaaccata actacatttc tttgtactcc
     9721 tattcttttt actaggctag aaactctctt tgctactgaa gtatgaatac ctgccactat
     9781 atcttcaatt tttgcatttt cagataaatg tgatataacc tcagactctg caaatactgt
     9841 acatgtactg cttattgata cttcattttg agaattcata gatatacttc cgagttcaga
     9901 tacatcaacc tctattattt ttgccattac atctaaaaat cttcctgtac ctgcagcaca
     9961 tttgtcattc ataagaaagt ttaatagtct tccattatta tctaatttta atacctttgc
    10021 atcttgacca cctatgtcaa taatggttct tgtctctgga attatgaaat ttacccctct
    10081 agcatgacag cttaattcac ttatttgctt atcagcatct gaatagttca ttcttccata
    10141 tcctgtaact acaacttttt taatatcttc tcttgcaaga cctgtcttgc catataattt
    10201 ttctaaaact cttgatggtc cagtagtccc agtaccagag gatattgttt cagaagctac
    10261 aatatcttcc ccattcttta agattactcc ctttgatgca gttgaaccta tatctaatcc
    10321 cattgtgtac atctttagca ttctcctttt aaaaaatcta gaattactaa ttaatatctt
    10381 acaactttac tatctttaaa gttatttatt ttctcttcat cgtagcctaa agattttaat
    10441 acttctacag tatgttgacc tacttttggt gctggtgtat attctttaat tccttcattt
    10501 ctaaacataa ctggagtatt aactaagaca cctgtatttc cgctatcgta tgttttctta
    10561 aataagaagt catttgccca agcttgttcg tcatctaata aatcttcaca gctttgaatt
    10621 ttttcaaatg gtaagtctgc ttcttctaat aaagctgacc actcgtctaa tgttttttct
    10681 aacatagctt ctccaactat cttaactaaa tcttcaacat gattaaccat tgaatctatg
    10741 ttattatatc tatcatcttc taatatatat tctctattta taaccttaca gaatttgcct
    10801 aaccacttgt tgtattgtat taaagctaat tgaatccatc ttccatcttt acatttatat
    10861 gtagtcatta atgggctgtt tggattttct cttgataaag gcatttcatt tccgtattgt
    10921 gctgttgtta tcattgttcc cattccatat atagctgtat ggaaaagact tactgttact
    10981 ctctcacctt taccagtttg agctttttta tgtaatgctg ctaaacttcc tgctgctagt
    11041 gctagacctg catagtggtc accaaatcct gctgctgtat ttgctggaga tgttcctttt
    11101 tccataacag attggctaac tcctcctctt gcgaagtatg cagtatagtc aaatcctggt
    11161 ttatctttta aaggtccttt ttcaccatat cctaatattt gagagaatat taatcctgga
    11221 tacttatctt ttatttggtc ataagctata cccatttttt ctaatgcttg aactctaaca
    11281 ttagttacaa atatgtctgc ttctgataat aatttatgta atatttctac tccttctttt
    11341 gattttacat taatacttac acccttttta tttccatttt ctaattcaaa catagggttt
    11401 tcatcatctg atgctggaga tttaaatgtt ccacccataa ctcttattcc atcaccttct
    11461 ataggttcaa tcttaataac ctctgcaccc cagtcaccta acatttttgc acaacatggt
    11521 gctgcgatga aacttgaaag ttctactact ttaactcctt ctaaaagcat aacgttttcc
    11581 tccttaatag tatcaattat aaaatttcga ttaaatcact cataaaatac ttttttctga
    11641 tattaactgt ctgatgtcaa agttcctaat cttatctaaa ataacttaaa aattattaaa
    11701 attatttttt attgttttat tgtcttacac ctatattgtt aagcatttat cgtgccaact
    11761 ttatatttaa tcaaaatatc gcttgatttg aatgtttttt aacaatatgc aattgaataa
    11821 tctttttcat atcgtggcat cttgccacta tccattgcat tttgctattc tttctatgct
    11881 tataaaagtt ttttttatat atttttttat gaaaaagctt gacatttcaa aaaaagtttt
    11941 cattgctaaa ctcaaaaaca catgttatca ttgtaattaa tcagcaagtt agttaactaa
    12001 tttcaaactt agataatttt ttaataatat ttaatctaaa aaataacaat ttctttgata
    12061 aattttagag taattattac attaaataaa aaattactaa atatcaaaat aacacaggga
    12121 aaacaatttc aaaactaaat ttttaacctt aaaaattttg tataaaaaat ataaccttat
    12181 atgctacata ttatttctaa atgaaaaatt accataataa tttaataatt acaggagggt
    12241 attgatatga aaatactagt atttggagca cgcgattatg aagaaccagt aataaaaaaa
    12301 tggtctgaag aacataagga tgttcaagtg gatatttatc ctgaaaacat gactgaagaa
    12361 aatgtagtta aagctaaagg gtatgatggt atatctatac aacaaactaa ctatatagat
    12421 aatccttata tttatgaaac tttaaaagat gctggggtta aagttatagc ttcaagaact
    12481 gcaggggttg acatgataca ttttgattta gttaatgaaa atggacttat cgttacaaac
    12541 gttccttctt attcacctaa tgcaatagct gaattagctg ttactcaagc tatgaacctt
    12601 ttaagaaaga ctcctctagt aaagaaaaaa gtctgtgaag gtgattaccg ttggatagct
    12661 gaacttcttg gaacagaagt tagatctatt acagttggtg ttataggtac aggaaaaata
    12721 ggtgctactt ctgcaaaatt attcaaaggc ctaggagcta atgtaattgc atttgaccaa
    12781 tatccaaata gtgatttaaa tgatatatta acttacaaag attctttaga agaccttcta
    12841 aaagaagctg accttataac attacatact cctttacttg aaggaacaaa acatatgata
    12901 aataaagata ctctagctat aatgaaggat ggagcttaca tagtaaatac tggccgtggt
    12961 ggtttaatta atacagggga tttaatagaa gcactagagt caggaaaaat tagagctgct
    13021 gcccttgata catttgaaac tgaaggattg ttcttaaaca aaaaaatgaa tcctggagaa
    13081 ttaactgacc cagaaataaa taaacttctt tctatggaac aagttatatt cactcatcac
    13141 cttggtttct tcactagtac agcgattgaa aatatagttt attctagttt aagtagtgct
    13201 gtagaagtta taaaaacagg aactgctact aatagagtaa attagtattt tataaatata
    13261 ttttttcatt aattagctat tatctaacaa aatagccttt aatttcccaa atataagaga
    13321 gtcagctcag tatatattga gtagactctc ttatattatt ttttatatta aacttgtact
    13381 cctcttattt ataccaaatt aaatttatat taacttactc taactactcc tactctatac
    13441 attttaccta tttttacttt tctaattata tacatttgaa tgggtacaat ctgtatttta
    13501 caaaaaaaac acctaacaaa ctatgaaaat tgtatgatta atattaatat atttataaga
    13561 aaacataaca attatgttag ctctggattt ttagggaggg agtatattgg aaaaaatgaa
    13621 taaagttact tctaaaaaaa ctacctatat tgttacttca gcattatttg catccataat
    13681 atgcctgaca atagcatata tattacatat tccagttggt ggaaacaatg gatatgttca
    13741 tataggagat gcttttattt atctagctgc aactattttg ccaacaaact atgctatagc
    13801 tgcttctgca attggtgctg gtctagctga tttatctaca ggtgctgcta tctgggtaat
    13861 accaactata atcataaaac caatacttgt attatttttc acttctaaaa gtgacaagat
    13921 aataaataag agaaatatag ttgcttcggt tgtagcaggt atagtaggat tagttttata
    13981 catgtttgct gaaggtataa ttattggaag ttttacaagt gcatttgtaa tgagcttact
    14041 tggcttatta cagccaatag gaagttttat tgtttttata atcttaggta tggcacttga
    14101 taaacttgat tttaaaaaac gttattttaa ttaagaattt aaatttatgg agggaaaatt
    14161 atgaatatct tatatacaat tgaaaatagt atctatgtaa atataactaa tacatgtcca
    14221 tgtagttgtg ttttttgtat aagaaacgaa aaagatgaag ttgcaaatag tggtagttta
    14281 tggttggagc atgagccaag tgtagatgaa gtaaaagaag ccttcaataa atacaattta
    14341 gacgactatg atgaaatcgt attttgtgga tatggcgaac cattaatgag aataaatgaa
    14401 ttgatagagg tagcaaagtt tataaaagaa aaaagtagca taaaaataag aataaataca
    14461 aatggtctaa gtgatttaat acataacaaa aaaacagcta ttctgttaaa agatgttata
    14521 gatacagtat caataagtct taatgcccca aataaagaag cttataatag agttactcaa
    14581 ccaaagtttg gagaaaaatc atttgactat atgttaggtt ttgcaagaga ttgcaaaaaa
    14641 tatataaaag aagtagcttt ttcagtagta gatgaaatat ctccagaaga aatagaagaa
    14701 tctaaacaac tggcaaaaaa acttgatata ccattaagag ttagacataa gaattagcaa
    14761 gtaaaattat aaaacattaa gaatcacctg aatggtcttt caggtgattc ttcctcttgt
    14821 attaacattt tacaaaatag atttcatacc acactaggaa tgtgtaaatc atccaaatct
    14881 ttctccaatt atcagagttt ccactaatgt agtcattaaa aatctcatta atctcatcta
    14941 tgttaaagaa tttatctgct atctcactat tgaatttatc tcggatatcc ttattatatt
    15001 ggtcatcagc catccatata cgaattggca caataaatcc taatttattt ctaaaagcaa
    15061 tctcttctgg taatgttttt gatgcagctg tacgaaaggc aattttattc tcttttcctt
    15121 tcactttata ttctgatggt attctggatg caatatcaaa tattcttgta tctgtaagag
    15181 gcattctgac ttccaatcca actgcagtac tcattttatc tatattaaaa taaatatctc
    15241 cttccaacca tatttgaata tctacatttg acatgttagt aagtgtatct agttcttctg
    15301 tttcttcata aattcctttt accacttcaa taggaagcac atcaggattg tatttcttaa
    15361 gaatttttct tttctcaccc tcattcataa tgtttgtatt tccaatataa aatgtcttca
    15421 aattctctcc ataacactct gccttatggt atatattata tccaccaaaa aactcatctg
    15481 ctccttctcc agagtaacag atatttgtgt tttcagctgc tgccttgcat ccaatagcaa
    15541 aaacgatagc agatgcatct ccagttggtt gctccatatg gtacattaca taaggtactg
    15601 acgcaaaata ctcttcaggt gtaattatat atctcgaatt tttacaccca agaatattag
    15661 ctgtctgttg tgctaatttt gattcatcaa aacgctcttc ctcataacca catgaacctg
    15721 ttttttctat atctgacatt gccaatatat aagatgaatc aacacctcct gataagaata
    15781 actctgcagt ttcattctct gattttacct ctggcataat tttctgaagt gttgtatgaa
    15841 tttcatccgt ccattcctca atagacttgc tgtggtcagg atgaaattca ggtttccaat
    15901 aacgaccaat acatactgtt ttattctgat agacaaggta atgtcctggc ataagcttct
    15961 ttactccacg gaagaatgta ttttcacctg ctacatatgt gaaagacata taaatctgta
    16021 acatgtcttc atttaactct ttcacaaatc ctggttgctc cataatctta cgaatagatg
    16081 aaccatagag aagcttccca ttttcagtct cataataata gaaaggtttt actccaaact
    16141 ggtctcttag gcagaagagt ttcttttcca cagtatccca taatgcaaag gcaaacattc
    16201 catgcatgtg atttgccata tcatatcccc atgtcttata tgcttccact aaaattgctc
    16261 gttcacgctc atctctacat aatgaagaat cgattccaag ttcttcacag agaactttcc
    16321 agtttcgaat atgtccattg tattctagaa tttttatcat atatgtgtct tttcgtgtta
    16381 aatacttttc ttctaaattt atcatatgtg tatcctttcg tattaaaaca tttaacttct
    16441 aaatttatta aatgtttata tatatttatt cacttataat cactgaaaaa tcgacttttt
    16501 tcaaagtaaa ttctttttga attagtacta atctgctctt tattaatggc ataaatatga
    16561 ttatcaagta ttatcagtgt tataacattg aattttttat tcttcataaa tattgccccc
    16621 tttatattac caactaaata taatatatct tatgttactt acatattctt taagaaattc
    16681 tgaagatttt ataaagtttt ttgtattata attaattaaa aataaaattc tagttataaa
    16741 acatattttc cattaaacaa aaaaatagtt aaaataaatt cataaccaca taaacttatt
    16801 ttaactattt gtatatttta attataaata ttaacttaaa tttttaacag gatacactca
    16861 taaaataaac ataatgaaca acaaaataat atgtctcagt ttctttatat actttacctt
    16921 ctttcaattt tctaccatgt agacgtataa gataatatta gtaattcact ctattgctta
    16981 actcgtgcga tatggacaac caagaaagct atttcctcat ttgttaactt ttttccatat
    17041 ttcttttcta aaaaatctct aacttttaat gcaattaaca tttcttttgg atttgacctt
    17101 ttcatttgat taaataataa atcatcacca ctgcttaaca tactatctga aaaaaatctt
    17161 tccacaaaaa attttatatg tgttataaat ctcatataat gcatactctt tttatctaag
    17221 gttctattca aagaaaaaac aaaaatatta attatttctc caattacttt ggcatactta
    17281 atcgtatcat atgaatttcc atctgaagcc atagcatttg caaaatggaa agcaatgtta
    17341 gctgcttctt cctctggtaa ttgaatgccc aatctctcct ctaccatata aattgcaacc
    17401 attccaacct taaactcatt tggataataa ttttttattt cccaaaatac tcgatttgta
    17461 atttttattc ctttacgcat cctttcaatt gcaaagttaa aatggtctgc taatattaag
    17521 tataagtttt tattaaaaga tgagttcaat aacttttctg cctctactat tatttcctgt
    17581 gttatcttta aaatgtcgac aggaatatca tccattaatt ctaaaaattt ttttgatttt
    17641 gtattttcaa cagggacaaa catttgatta tcattggaac cacaaatata ttctcctgtt
    17701 tttttaccat atccaattcc tttccctagc aaaataaatt cattatactt tgcatcatga
    17761 actaaaacaa cgctcgagtt caaaactttc tttattatgt agttcatttt atttgctcac
    17821 cttctattgg tcatttaaaa tctatactat tattttcaat tactttttta taccaataaa
    17881 aactatcttt cttatatcga ttatatgtcc cctttccata atcatcagca tccacataaa
    17941 tatatccata acgttttgac atttgtttcg ttgattcact gaccaaatca atacaacccc
    18001 atgaagtgta tccccaaagt tcaacgccat cttcgataat cgcatctaac atacatttaa
    18061 agtgttcttt taaataatta attctatatt ggtcatgaac ttttttatct tcagttaaaa
    18121 tatctttagc tcccaatcca ttttcaacta taaataaagg ctttctgtat ctatcatata
    18181 attcaatcaa agatatacgt agacctattg aatcaatttg ccaaccccat tcactcattt
    18241 ctaaataagg attttttaca gctaataacg tattcccagg tgtaatatct aatccagttg
    18301 tatcagctgc ctcacaagaa gacatatagt aagagaatga aataaaatct actggatact
    18361 ttttcataat ttcatcatca tgttcttctt ttgctatttg aatgttatta tttttaaaat
    18421 acgaaagtaa atatactgga tactcaccaa aaacctgcgt atcactatat gcataaatac
    18481 ttctcatttt ttgttgagtt gccaaaacat cttctggtct acatgtatat ggataatacg
    18541 ttaattttgt taacatacac cctacttttg aatttggaat aatctcatgg caaatttttg
    18601 ttgcaagggc actagctaca aattgatgat gcatagcttg aaaaataact tcctcaaagt
    18661 ttttatcctt aaaacggtct cgaactaaac caccagtagt gtacggatga cgaatcatag
    18721 aatcaacttc attaaatgta agccaatatt tcactttgtt tttatatctt tcacagatag
    18781 tttctacata cctaacaaac atattgataa cttgtcgtga ataccatcca tcatagttta
    18841 aaacgatatt taatggtggt tcataatgtg acatagtaac aagtggttca attccataac
    18901 ttatcaactc atcaaataca tcatcataaa actgtaaacc ttcttcattt ggctctttat
    18961 catctccatt tggaaaaata cgagaccaag caatactcat tcgatatgtc ttaaatccca
    19021 tttctgccat tagagcaata tcttctttat agtgatgata aaaatcacta ccatgacgtt
    19081 ttggataatt tacttcatct tcaggatgtg ctaatccttc ttctatatct tttgttgtga
    19141 tttcattatt agatttatag tctttcacat ctgcatcaaa gtgtgccttt gctacatctg
    19201 atacagacca ccctttacca cctaaattcc aaccaccttc aaattgatta gcagctgtag
    19261 ctcctcccca aagaaatcct tctggaaact ttctcatatt tatattcctc cctttacatc
    19321 aaacaagata cttccttttt ttacattgcc ataagactgg tttaacactt tataagcata
    19381 atctgctcca ttattgttta caatcataac agttgaatct aaattagcat gtgagatttt
    19441 gtctaaatca aattgaatta ataaatctcc ttcttttaca ttatcgcctg tcttaacaaa
    19501 tgttttaaat ccatctccat tcatacttac agtatttatt ccaatatgaa tcaaaatctc
    19561 agccccattt tttgttctta aaccaattgc atgttttgtt tcaaataaca tcacaacttc
    19621 tgaatcacaa ggtgcgtata aatttccatt ggtcggtata attgcaactc catctcccaa
    19681 agtcttactt gcaaatagtt catcattaac cttacttaaa tctattactt ttccttctac
    19741 tggagttact aagatattta cttctttttc ttcttctagc tcttcttcaa caacatctcc
    19801 aattgatgac tctactgtat ttgtatcttc cttccaaata atcagtgtaa taataaacga
    19861 gcctaatatt gcaataacaa aaccaatact cgcaaaaatc aaattgtttc cattgtttgg
    19921 gtcaataaac atactcatac tggcaagccc tggtccaaca attacaaatc cttttactgc
    19981 aaataatcct aaaaatgtac cagaaattgc acttgagaat acaacaccta acattgctct
    20041 tttatgttgt aaagtaatac catataaagc tggctctgta attcccatca aggcagaaat
    20101 tcctgcagat aatgctgttt gttttaatgt ttcatctttt gttcgcaagg ctactgcaaa
    20161 acaagcacca ctttcagaaa tattgtgggc taatgaagat gtcatatata aagcttcata
    20221 acccaacttt ccaattgtat taattgaata aggtattagt gctttgtgca ttcctgttgc
    20281 aaccataaat ggaagaaaag cagcaagtaa tcctacaact aagaatccca ttttgttata
    20341 taagaataaa ataatggttg taaaaattgt accaacgtta tatcctaaag gacctaaaat
    20401 agttagagta attggaacag taattgccaa agacatcata ggaacaaaga aagttcgaat
    20461 tggttttggt gaatacttgt taaaaatttt ctccattgtt gccaaaaaag acacacataa
    20521 gatagccggg aaaacttgtg cattataggc aatgtttgga attgtaaatc caaatagttc
    20581 gacaccttca cttaaagcag ttgttgttgc tggaagcaat aagtatccta cagcggcaat
    20641 agctactaaa cgattacatt tcaatacatt ggcagtagtt acagctacca taagaggtag
    20701 gaaatagaat gttgcatctg aaatagcaac taataatgta tatatagtag aatctgattt
    20761 taaaatatta aacattgcta ataacatcaa cagtgatttt aaaataccag ctcctgcaat
    20821 agcaaaaatc agtggttgaa aaatattaat aataaattct ataaatcttg ttcctaagtt
    20881 tattttttct tcagttttta cagtactatc atttgtatct aaagggcaaa cttttaaaat
    20941 ttcatcatac acatcaacaa cactatttcc aatgacaact tgaaattgtg ccccattaac
    21001 tatactcata acaccttgta ctttttttaa agcatcctga ttgactttac ttctatcaat
    21061 caacttaaag cgtagtctag ttgaacagtg ttctaaagct aaaatatttt ttgaaccacc
    21121 aacttgttca ataatgtcaa tggcagtttt tttataattc atcttgtaat ctccttctcc
    21181 ataatttttt atgaatggcc attcaagatg caaaaaaggc agaacctata taaacacctt
    21241 gaaaaatcaa agcaatatat tcgatcctgc ctgcattacc agtaacatgt cttctattta
    21301 tactattttg tattattata ttaacatttg cctaaaagaa ttgtcaatac ttttttaaat
    21361 tttctgatac taactaatag cacctttata attcattttt tatgtcaatt aaagtaacag
    21421 tagccaccca ccaattagta tcaaaattga acctggtatt ttttctttta tattttcttt
    21481 gaatataaaa tgagcaagta ttaaagttat tatcatagat acttgagaaa atggctctgc
    21541 tatactaagt tctagattat ttaaagcaat taataatgct aaataagaat atccattaat
    21601 agcaccactt aaaattgaaa gccccttttt attactaaaa atctcacaaa ttattttttg
    21661 tttcttttta aatgctaaaa agataaataa atttaaacct acgaaaaaat acagtatagt
    21721 tgaatataat ataggagata cttgtacaaa aaaagcctta tccaatactc ttcctactga
    21781 ctgcaaaaat atgtataaaa acattaatct acatggtaaa ttgttaaaaa ttacagagac
    21841 attctttaaa aaagagctta ctttttttaa tataaacact ccaccaatca taattatgat
    21901 tcctgcaact tttgctaaac ttaaaccttc acctaaaaat ataactgata aaagcagtaa
    21961 aaacaatgaa tttaaactat ttattggagt aacaagtgaa acttccccag ttgctaaaga
    22021 cgttacatac gctactgaac caattgaata gactaaacta cttatataac atggtattaa
    22081 aaacgaccaa tcactaactc tatccattat gctaaatgga agtaaacata ctccccctat
    22141 aaagaaaaat agaaatgatg aagctatatt tttataaata tctccttctt catcacctaa
    22201 taatcttaca actactcttt caaaagctaa tagcactact ctaattaata atgcaaaata
    22261 agataatatc atttttgacc tcgcttaaaa attaatccga cttattgtta tattaactgt
    22321 ataagactac catataggta agtctttggg attttttaat attttatgtt taaatacagg
    22381 tacattaagt ttttcaccta gtttacggca ttgctcttta taggtacctt ttaatttatc
    22441 atgaaaaact atacaatcaa ttccaccttc aatactattt atacactttt ctagtttctc
    22501 aaatcccgat tcatcatcat acattccact tacaatccat tgatttggca atacatgtcc
    22561 aattgatatg ttatattctt tattttttat aatatctgag aaagatttct caaaatgtac
    22621 ccctccaaca cataataaag tcttcaaagg ttcatcacaa tcaaatactc taattaatga
    22681 ttttgccaat acctgtattg ctatactatt attaaaacta tcactactac ttcctatctc
    22741 aatatccaac ataggtacag aatattctgt aattaattta gattcttcac catatgttgt
    22801 tccagaccag tgagttgctt ctgttaatgt agtaaattca tcaagtagat tttcattttt
    22861 tatatcctca atagcattga ttagattttt aaagtatctt ggatttgaat ttccaaattc
    22921 tcctgttgga acatctccaa ttgtatgagc tgttaggata tgttctggag cattttctcc
    22981 ctcatgccaa tttacaactc ctgcaaaatc ataatctctg aaatgtctat ttaaaattgg
    23041 aagataatat ttataattat gacttattac atcttttgtt tttacaaaat gaaataagtt
    23101 attgttttta tccttaaatt ctaatacaaa attatcatca ataacaatat cagtttgatt
    23161 taaatccatt atttcttcac aacactttat cacattactg gctactgggt ctttctttaa
    23221 atcactacaa aagaaaaaaa ctgctttttt attattcatc cataaatcac actcctataa
    23281 cttaaatata atatatcttc atacctaaaa tcatctaaat atcactctaa ttccattaaa
    23341 ttatttatat ataatatact accatactca ttttagctat acctttgcct gagtttctat
    23401 atatatgtga tacatcagct ttaaatctta tagaatttcc actagataca atgtaatctt
    23461 ctccatttat tttaatggtt acttcgccac taaaaacagt tataaactct tgtgttcctg
    23521 gaagttcagc atttgaatct aaatttccac cttcttctat ttcaatcata aatatctcaa
    23581 atcttctttt ggagtcaaat ggaaatattg gataacttat atactttcca ttatcttcaa
    23641 taaaatggtc tatatcactt ttttgaatca attctatgtc actttcctgc ctctccatca
    23701 atgatgtaaa tgagattttt agtccattag ttattttctt caaagtagat atagtaggat
    23761 ttacctcaca cttttcaatt tgagatagca tactcttact tacaccacta agttgtgcaa
    23821 tcttgtctaa actaagatgt ttttctttcc ttatcttttt taaattttca gcgattattt
    23881 catttaaact ttgcataaat accccctaat acatactaat ataagataaa ttattttgat
    23941 tattaaataa acttagtaat ttaatagaaa ctttttatcc attatactgt acattatgtt
    24001 taatatacat tacttttttt agaatgtaaa tagttttctg aaattttgtg aaagtgaaca
    24061 aataaaaaac tagtaaccta tatttttaca aggctactag cttttattat aataatattt
    24121 cattttaact ataaaactta gatgcaccta taagctgtct cttagaaaca atcttagcta
    24181 ggtttgctaa tgaagaaatt tttatatctt taaaagaaac taaaaataca aacttaaaat
    24241 ctgtaaattc ttgatttata ttgtatatat caaaataaca tctcaaatta tcaaataagt
    24301 aattatcttg taagtctgct tctatctcat cagtagcatc ttttaaatac gctcttacat
    24361 cttcaaataa aacactgaaa taagactcat ctatttcttc acctaactct tccaatattt
    24421 cttctatatc taaatcatcc atatcaaaag aatttcctgt caactggcaa tcaaatacca
    24481 atatattttc ttgatttata gtatttgata tatcttgtac atattcgaag tctggacgta
    24541 attctaaaat gtcttttatt tcactgctct ttacatggat ttttcctttt ctattttcaa
    24601 tttttaaatc tatcatatgc tccccctttc aatctacaaa tctttaaata ccttgtttta
    24661 taatcttttc aatatctatc caattactaa ctctaactat attttgatgt ttaacatctt
    24721 tattatagtt agtatccaga agtattactt taacaccatc atcagctagt tgcactgagt
    24781 ttaaaggatt atcttctata aatatgtcac aactcagttc tcttgccttt tcaactttat
    24841 aatcacttcc taataagtaa acatctatat ctgaaaatcc ttgtctcgat agccaatttt
    24901 tagttacatc agttaaacac tcatgtctag ccgttacaaa agataaatta tgtcctttag
    24961 ataatgtgct aattacctct gtagcaccct ctacaatctt tgcttcatca tatgagtgta
    25021 tatacttatt attaaactcc gcatacacat ctcttattcc cgaaccatac aattcttccc
    25081 aattatgtgt tatacactct gcttcagtta tatttttatt aaagatatca tttaggtatg
    25141 gaagaaaatg ataagggctt gttattgttc catctatatc aatacatata ttcaatttgt
    25201 tcatttttac ctccatgtaa catttattga tttgattaat caaatattat agcacagctt
    25261 taattataaa tcaaaactct ggatatgact atacctatat aataccaaaa agcttgcata
    25321 tttaagcaag cttttcgtaa attttacatt tttaactaat atataagttt ttctaaggtt
    25381 ggttccactc caaattgtga tttcagttct ttatattctt ttaatgcttt gtcattattc
    25441 gttttagttt ttatcgctct tatcattaaa ttttttggtg tatcaagtgg agatatgtat
    25501 tctactacag aagtatcata tccattgccc tccaataaca atgttcttaa accatcagtt
    25561 atcaaatctg caaatctagc tttaaataca ccatgtttta atattggttc catagcttca
    25621 tatctatatt gccctaataa ctccttatga caacatggta ctactactat agcttcagat
    25681 tttgctctaa ttcctagacc tattgccata tctgtagctg tatcacaagc atgtagactt
    25741 attacaaggt caacatccct attaggtgta taattagtca aatcctcttt tataaatgac
    25801 atatttttat aacccaagtt tttagccata ttttttgatg cttctataac tacatctgaa
    25861 taatctattc ctataaaata acagtttttc ttcaatactt cttttatata aaaatttaag
    25921 acaaagctta agtaagattt tccacaagca caatccaaga tagttataca gtctttatcc
    25981 tttatttctt ttaaaatact atctatcaat tcaacaaaat ggtctatctg attgtatttt
    26041 cttattttat cattttttat cttaccatct tttgtaagta ctccaatttc ttttaaaagt
    26101 gcatttgctt gtcctacttt tacataataa tctctgtttt ttatttgaga tgccgtaaat
    26161 tcatctattt taggtacttc ttctttatta tctaaatatt ttacatttac cttcttattg
    26221 tctccttcaa ttacaacaat agttcctcgc tcaacatatt taaatactaa tccatcataa
    26281 ttttctgcct ctttagaaat attcttaagc aactcattaa acgtatataa atctgatttt
    26341 cctttaaaat taaatttata tttattatct tcctctattg caattccttt aaactctttt
    26401 cttccagatt taaaaatcac ctctaactca ataaaaaaat gcctattatc aaggtttctt
    26461 tgagtaatcc ccataaaaaa catatttagt tttcctatac tctgtttatt catcataatc
    26521 tcccttttaa cttatatctt taaatcttat taattaatat tatttgtttc tgaattattt
    26581 atttcttctt ttaaatcgtt caatctattt ttaaaacttt ctatctgctt atctgataaa
    26641 tcaagatatt ctgttatctt ccctatatat ttagggcttt tagtatttat taatttcaaa
    26701 gcactttcca tagatttttc tctaagctca tatgctttct ttacgtcatc tctagcatta
    26761 ctcaatgttt ctgtatactt ctccttagaa agttctggaa tctgcatatt ttcatattct
    26821 tttacaactt ctttacactt gtttctggca tttgtaacat ctttttttat actagataat
    26881 ttagttatat tttttgctat atccttagtg taaggtatac attctctcat tggaactaaa
    26941 gctgctcttt ctatattata aatttctttc ttaaaaattc ctatactttc catatctatt
    27001 ttttttatat cttcactatt tttttcttta cttgtatatt tattattttc ttttgtatta
    27061 tcttcttgtt tttctgattt attattcact gaaacattac tatcagaatt attcttttct
    27121 tttatatcat tacttccttc ttcattactt tctttatttt gtatatttct atcttgtttg
    27181 ttgtttaaat ttttattatt tgatatttct tcattctttt tattatcctg ttttaaatcg
    27241 gtactttctt tttccttaaa atttgataca tacttttcat catatgtctc atcagaaata
    27301 taattgtgat aatacataga ctcttttatt ttattaagtc cactcatata aatattactt
    27361 atcattattg ttgtagctaa taccacataa atactactgt agatacaaga cctcttaaaa
    27421 ttcttgtaat ttctgaatat cactactaaa ggaataagat ataaaaatat aaaaactaat
    27481 atccacctca taagtcgtgt ctcctttctc aaaaccgaaa tccctcaaat atttattttt
    27541 aatcatgtat cttatagtat ttaccaattt atgtttttta atcgtgaact tttattaaat
    27601 taaattctgt atagtcacaa gatgctaatg tatattctac tccatttcga atccccttca
    27661 atcccatttt aaaagattct ttaccatgca agtgaccata aatcaccttt tcaacattat
    27721 attcttcaaa taactttgta aataaagatt cttccaattt atcattcgta ggaggataat
    27781 gagtaatcac aattattttt gagtgaccac ttttacgagc agattctaat gatagtctaa
    27841 gtctatgctc ttctctttta taaacttttt catcagtctc atcaaattta acatcattag
    27901 gacatatcca gcccctacct ccacaaattg cataatcttt atattcataa aaatttgtct
    27961 gaataaaacg catgtcttca tatagcttat ttaaacttgt aacggttgtc caccagtaat
    28021 catgatttcc ttttataagt attttctgac ctggaagttt gcttattata tctaaatctt
    28081 ttttagcttc cgataaatta attccccaag atgtatctcc tagtactaag accatatctt
    28141 cttccttaac aacttctttc caattatcta taattttctt ttcatgacca tcccaattac
    28201 ttccaaagat attcattggc ttattgactg atgttgaaaa atgtaaatca cctatagcat
    28261 acaaactcat aatatcattc ctttcttaat tacactaaat aggctgtctc tttttagaaa
    28321 ttattttcca ttaagaggca gccccattaa tatttagcaa attttctaca agtagttttt
    28381 tactgaacta ctttatcatc taccttagta tccttatatt gctctagtaa tatatctatt
    28441 tcttgtttta attccaaaat ttcagttata tttttatctg tttcagttct atcaagtttt
    28501 ctttggtact gcatagcttt atgtgtatca cccaagtcat ataactcttg tattctattt
    28561 agagtatctc taatagctat agacttcatt tggtacatag cctgagcttt cattatgtcc
    28621 tctcttattt cactcatttc ttggtctaaa agaaaggcag catcagatgc tcttctaagc
    28681 ctttcagcaa gagtctcagg tatgtaatgg tcatatttat attttaatga atgttctatt
    28741 gtagcccaga aattcattgc aagagttctt atttgtattt cacatataat ttcctttgaa
    28801 cccgcaatgg agtttatagg gtattttatt ataacatgat agcttctata accactatct
    28861 ttgtaatttg taatataatc tttttctcct attatagtca tatcatttct tacttttatc
    28921 aaatcaacta tagcatatat atcctcaaca aactggcaca ttattcttat accagcaata
    28981 tcatcaattt cagtttctat atcttttgca tttatccttt ttaacttaga tattatggaa
    29041 gatatttttt ttgttctgcc tgtgacaaac tctatgggag aatattcacc ttttgctaaa
    29101 tattcttttc ttatattttt aaattttatt ttcaattcct ctactgcatg ttcataaggt
    29161 gctagtatct cattccattt ttcgtattcc atattgctca ccctttattt gttttttatg
    29221 accttcttta ttttatcata atttattttg tttttgtata gtaaagcaat tctccatttt
    29281 ccaatatata ccctatttct tctaaatcaa ctaagtaact tatgacagat actaacgaag
    29341 atttaaaaaa atgatactct ttataattat tgcttaaatt attgttattt ataatgtttt
    29401 ttaataaaat ttctaaagat ttcggttcta caagcaactc tcttatttga tataaatatt
    29461 tttttaaagc attcaaatgt ttttctatta atttataaga atcttctttc gatataactt
    29521 gcttgccatg ccctaaaact aagtactcaa aatctatatt ttttaatttt tctaatgaat
    29581 ttatttgttc ttgtatatca tatagaaaca agaaatcgta ttttgataga atttcatctc
    29641 ctatcaataa atcgccaaca aaaatcacat tatccttcgt caaaacagct atactaccag
    29701 gtgtatgacc ctgaaactca attatatcaa acatttcatt gtttaattca atttttccaa
    29761 cttctataga tttatctatc tttatatcat ccaacatttt attttttaag atattatcca
    29821 taaatacatt gctctttccc ccaacaatat actttgaaaa caattctgga ttttctatat
    29881 ataatttgtc gtattcagat gacattatac acacatcttt ataatattct ttaaattgat
    29941 tacaagctcc atagtggtca tcatgaccat gagtatttat aatatatcta acctgtatat
    30001 tattttcatc taatacttta tttactctcc taggtcttga accacataac cctgggtcta
    30061 tcataagtgc tgtgttatct tcaaatacat atattcctgt attcgtgcca ccttttataa
    30121 aaaaggtatt tccttttact tttgtaagat tcaccttcct cacctcattt tgacaatatt
    30181 tatgatacaa tttattactt actaatataa aactatacaa gaacaattct ttttattcta
    30241 tctatagttc tttttcttat tttgtattct ttagatatcc ttattttcac attatatgct
    30301 aaatttctat aaagtaatga ctctataaaa tattcaacta tacctctatc cctaaagtct
    30361 atatctatat ttccacttga ataaatattt gagtctaata tcataagctc atcaaaaaag
    30421 cttaatctct tagatttact taaataatct ttatttggaa taaatctatc acaataatct
    30481 atcctgtaat ttactacttc atcatttatt tcaaatccat attgcttttt cattaactct
    30541 ctatagttat tatttttctc aataacatta tctaaatttt tattataatc ctcttttttc
    30601 caatgtccaa acatcctaca atttaatggt ctaacttcat atattagaca tctattatta
    30661 gtatctttaa atggacatgg gttctttctt gtatactcct caaaataata atctaatatt
    30721 ttacttatac agcttttttt taaatcaact ctatcttcaa gataacaaaa tatattcaaa
    30781 aactcaatta aatttatacc tactgactcc atacaacaat ttccacatcc agaacaattt
    30841 cctactggca aggacttata tacatcattt agtttgtcaa agagcttatt tttaatggaa
    30901 taatctatac aatttaaaat atctttattt tttatactag tcattattat tactccttgt
    30961 tataattatt aagttaatac aaacaattat tataacatat tttttaaatt taatcgcata
    31021 tggaggtatt ttatgaatag atatacaaaa ataattaata tgatgggaag ttattacaca
    31081 aaagactttg aaaaagaaaa aaagaatgta ataaaagtta gagaagttaa agaagataca
    31141 gttagaaaat ttttcttgca aggtgactgt gaagttcttg tagtatttga agacactggg
    31201 aaagaaatac ttattgatga cttttctcct gaagaagata tcaaaaaata tttaggaaca
    31261 aaatttataa ataaaaaaag atagttatca aaaataattc taaaattaaa atttaataaa
    31321 tgtacagtta taattctata taattatagt taaaagttat cttttattgc ttttttagac
    31381 tttaagatag ctttttttct attttttgta aaataattcc ataattcaca ttaataattc
    31441 acaaaatgat ataatataac aaatagataa attttaaatt tctaaataca taattaatat
    31501 tttgcgaggt gattttatgc aaatttattt tagagttaag gctgttggca aacgcaaacc
    31561 tatgttagaa cttacccctt ttgatgtatc tgacaacatc aattgcctaa aagaagctat
    31621 ctctgaaatt gtatctaaaa atgttcttga atataatgag aaaatcccag aaaaatcaat
    31681 aataaacttc ttaactaatg aagaaattga atctcaagct gatattggaa aagttggatt
    31741 tggctctatt tacaatgaga ataaacaatc tgtagaaaag gcaatagaag tagcgttaca
    31801 ggcatttgaa gatggaatct acaaagtgct tataaatgaa gatgttattg aaaaactcga
    31861 ttcccctata aatctgaaaa gtggagatat atttactttt ataagactta ccttgcttgc
    31921 tggaagaatg ttttaaaata aataatttgg aggtacataa atgttagaac gtactagagt
    31981 agaaaaaaat cctaaaataa ttgaaaattt taaaaataat tttactaaat cttcttcaaa
    32041 acagtactac gacttagcaa aatctctttg ggactgcata gaaaatagtt catactatta
    32101 tagagaacct gaggacaaat tcttaaatat gataaagaaa tactacaatt gccactacta
    32161 cgaaattaaa aatatggacg agctcctttc tggaccttta aaaaatgcat tagaattaat
    32221 atttacttct gaacaagtag aagaactttg ccaattaatt aaaagaaaga tggattatac
    32281 atattcagga ggatattatc gtaaagggta tcgctcaaat aaacttgtgg attattttag
    32341 aggtattata aggtttattt caaactatgt tgatttaatt tattatgatt tttcagttat
    32401 agattatctt actcttccaa ataaggtctt gtactatgac tctataatga gtgataaaat
    32461 agcactagaa atagacaaag gaaatcaaaa agtaacaagt gccttagaag aagtaatatt
    32521 tggagaaaat caaactgctc tacttacaag acaaatgata attggtatca tgaagagtca
    32581 tagtgataaa tgctatgaaa tgctttctaa acttcttttg gcagccaaac aacaagaagg
    32641 acttagacag caaattgtag agagtttaga tgagggtaca atttctgcat caatatacat
    32701 gttaaaaact attttggaca acaatttaga gcgatttagt tctgttataa gagccttgga
    32761 tacatggaca ggacttggtt tttcagacca aaaacctgga ataatacgta aatgtttaga
    32821 actttcatat aaatcattga ctgatgaaaa gttccgtata gaatcaatta atagcaatga
    32881 taatcttgaa atttattttg ccttatgggc tactgcaact tacaacatat atgactctta
    32941 ctctcttatt gaaaacttac tttcttgtca ggaaaaatat aaaaaacttg tagctcttta
    33001 ctttttatcg catacagaaa gtacatattt taaacattct atagcatcta aaaacattaa
    33061 gggtgatgat ttagagatac tagcatgggt aattacaaat ttctatgtag aaggttctgt
    33121 tggctactac tatagttggc aaaacagaga aactaatttt gacttgtcaa acactcctat
    33181 tgacaaagac tttgatgcta gaaaagaaca atttgaaagt ttaaaacata ctttagaaat
    33241 tttaaattca aagacaaaat cattttcagg aagtgtattt ccatggactt ggattgaaat
    33301 ttcttctcat gaaatactta aatgtatgat gactttaaca gcatacgata tgaatgctca
    33361 atttatagat gtgcttatgg aaaattgtca tcttatgagt tcagatttaa gagcttcact
    33421 tatagtcaat tttgtaaatg aaccaaagac agatagacaa cgtgaatttt tattggaatg
    33481 tttaagtgat aagagtgttt ccaatagaga aacggtattg agtttactta gaaagcttga
    33541 gctaacagat gtagaattag ataagataac caatctattg tctttaaaga caagctctat
    33601 tagacaaaca gtaataaaaa ttttacttga acaagatgat tcaaatttgg aaaatattgc
    33661 ttcttcactg ataaaatctt caaattctca aaaatgcctt ggaggtcttg aaattgtaaa
    33721 cttattaaaa gacaattctg atagacaaga actatataat aagcttattt tacttataga
    33781 ggatattgat aaatctaaaa agaatacatc tcaagttcaa atattaattg ataatttgtt
    33841 aggtaaagca aaaaatgatt actgcaaaga aaatggtttt ggaatatata accctgaaaa
    33901 caaagttcaa attccagaac aatttgattt taaagatgat tctaatagct catcaaagct
    33961 taataaaatt atttcaaata taagtttatc tactagtgag gattctgttt ctgtagcaac
    34021 aaaaaaagaa gcaaaaaaaa ttctcgatac ggatataaat aaaataataa aagtttatga
    34081 aaaatttgat gagcttatta ctgaaaatgc agattatgaa tatgaagttg aaagatggtc
    34141 aggtaatgta gacaaagtgc ttttaggtta ttctacttat aacttgactc ctattaaata
    34201 taaagtttct aatgatactc ttgataatta tccattggca gaactttgga gagaaactag
    34261 taaaaagctt gacttagatt acaaattaat acttgatatc ttattttata gtataagtac
    34321 atgtggatat aatgaaacag aaaaaagttg gttttcatct atatattcaa atgtccttga
    34381 ctctaaaaaa caaaataaaa tatatacaaa acttgaaaaa tttaaattta atggacttac
    34441 aagaaaactt ttaagagttt tactaaatga gtttgaccat aaagaaatat ttaactattg
    34501 tttagaaata tactataaac ttagaaactt attgactata gaacaatgta aaaaacaaag
    34561 agttgaattt actaaaaact attacagaca aaatgaatac tgccctgctt taaatgcccc
    34621 tattttaaac tattggcttg ataaagcaca ttcgtttatt tatgatgata tttcttttac
    34681 taagtttttc tacactacgt tttcaaatta tcagttgcta gaatataagt ttcctttcta
    34741 tactagcata aatgtgtttg ctcgtgcaca tgaattaggt ttaatgactg aagagcaagt
    34801 taatagagaa atgataagtg gatacaacgc atcaaatata ataagaacat taacaaatcc
    34861 tagatgggct ggtgacacat tagaaaagta cccttggctt aaagataatt taaaaactgt
    34921 tacaaaccga attatagaaa ttgaatcacg tagaggtgat atgccaacag aagtgtctca
    34981 tctagctaat aatatacaat actttgaagg tatagattat tttgtaaata ttttggtcgc
    35041 tcttggtaaa gaaactttcc agagaggata ttcatatggt agcaattatt caaaaaaaga
    35101 tgttttaagt tctctactta aaaattgcta tcctactaaa gaagatgatt caaaaaaatt
    35161 aaaaagttta cttaaaaata ccgacattac tgagttaaga ttaatagaat ctgctatgta
    35221 tgcccctcaa tgggtaaaca taattgaaaa atatttaaac tggaagggtc tgaaaagtac
    35281 aatttggtac ttccatgcac atataaatga aggcttctct gcacaaaaag aatcagaggt
    35341 tgctctattc tcccctattt caccacgtag tttcattgat ggtgcatttg atgtagattg
    35401 gttcttagat tcatataaaa ctattgggga agaaagattc aatatacttt acaagtcagc
    35461 taaatatata actagtggtg gtaactctca tagacgtgca caactctatg ctgatgctac
    35521 acttggtaag cttgataaag acatgttgat gaaagaaatt gaaacaaata gaaatcaaga
    35581 taaattgaga agtttctctt tacttcctat gaaaaaagga gacctaaaag aagcaacttt
    35641 ccgttatgaa tttattcaaa agtttgctaa agaaagcaag caatttggtg cacaacgtcg
    35701 tgaaagtgaa tcaaaagctt gtactatagc gctagaaaat ctagctagaa gtgctggatt
    35761 tggagatgta aatcgtatga tgtgggctct tgagactgaa aaactaaatg aagttgctca
    35821 tctatttaaa ccaaaagata ttgatggtac ttcaatttgg atagatgttg atgaaagcgg
    35881 aaaagcatct actaaagttc aaaaaggcaa caagtcttta aagagtatac caaaagctat
    35941 tgctaaacat ccatatgtac ttgaacttaa atctgtccaa aaagatttaa agagtcagta
    36001 ttctcgtgca aaacagagtt tagaacaagc tatgaaaaat gaaatagtat ttacagttaa
    36061 agaaattgcc aatatctata aaaatccagt tatctgccct ttgattaaaa atctagtatg
    36121 ggtatgtgat gataatattg gatatgttta taatgataag tctaagttct ttatttgcaa
    36181 tatagaaggt gaaacttata agttgacagc aaaaaataaa ttaaaacttg cacatccagt
    36241 tcatttgttt gaatctggta agtggagtga gttccaacat gatttattta gtaagcaact
    36301 tgttcaacca tttaagcaag tattccgtga gtattataga ataaattctg atgaaatatc
    36361 tgaaaaaact atatctcgca gatatgctgg tcaccaaatt cagccaaaga aaactgtagc
    36421 acttcttaga aatcagcttt ggactgtcga ttatgaagag ggattacaga aagtatttta
    36481 taaagaaaat atagtggcaa agatgtttgc acttgcagat tggttttcac cagcagatat
    36541 agagcctcct actattgaaa cagtagaatt ttttgataga aaaacttata aaagtttaga
    36601 attagcttct atacctccaa ttctattctc agaagttatg cgtgatatag accttgttgt
    36661 aagtgtcgct catgctggtg gtgttgaccc tgaaactagc cattctactg tagagatgcg
    36721 tatagcaatt gctaaagaac ttttattatt attaaaaatt aacaatatca attttgaagg
    36781 ctctcatgtt cttatcacag gtaatttagg tgagtattct gtgcatatgg gttctggtat
    36841 tgtacataaa aaagggatgg gtgctttgaa tatacttcct gtacattctc aaagtagagg
    36901 taagatattc cttccattcg ctgatgaaga ccctaagact gctgagatta tgtctaaaat
    36961 cttattactt gctgaagata ataagattaa agaccctagt atcttaagca acttataaat
    37021 ataagattta tctctaaaac atattgggct ttctaatttt ccatgaaagt ccaatatgtt
    37081 ttatattata ttttatacga attaatttat aactatagca aatttatatg atatcttcat
    37141 catacatatt gtatatcact gaaaattttt ttcttcatta aaacctttta accctataaa
    37201 atctgtatag aaaatctttt tctaaagatt tatttaaagt agcactttct tgaaaattta
    37261 taaattttat ctctaaagaa gacttattta taggtataac cttatgtata agtcttaaat
    37321 ttactatgta ttgtctatga gtcataaaga aattaggagg taggcgtttt tttaaatcat
    37381 caaagttctc ataaaatttt atcgtatctt catctctagt atataaatta atagctcttg
    37441 aatttttctc aaacatgact atatcatcaa aattaatcat atgtatctgt ttccttattt
    37501 tatatacaaa aagagtatct tctataaaat tattttttgc aattttatga gagttaatgt
    37561 ggtctattgc tatattaatt gaatcaagta ttttttcttt tttaaacggc ttaactataa
    37621 aatctatagg atgtacttta aagctctcaa gactatagtc agcaaaacct gttacaaaaa
    37681 ctatatgtat atctttatct atagaaagaa tttctttggc agaatcaatc ccatttttat
    37741 atggcatatc aatgtcaata atcaataagt ctattttctc actttttata aattcaattg
    37801 cttctatacc atccttgact ttcttaacat aatctacata tccggactct ttaactatat
    37861 ttgctatatc atctcttaca attttatcat catcacaaat caaaactttt atcacagact
    37921 tctctcctcc taactaataa tattttggta ttaaaattac aaattcagtt aaaaaatcgt
    37981 cactatttac aagtatacta taatcatact tatctagtat atttttaact agatataacc
    38041 caaaacctct gtcttgccct tctttagtgc taaatccatc caaaaatata ctttcgacat
    38101 tatgtatttt aggaccatta ttttttatgg ctataatata ctgaaattca tcttcatatg
    38161 catgtaatct tatatacttc ttttcctttt gtatagcaga caaagattct attgcattgt
    38221 ctattatgtt taatagcact gaactcatat cattaggttc aatctctaaa ttatccataa
    38281 aatcttggat atatacatca aaagatatgt tcttttcaag acattcctca tattttaagg
    38341 aagctatagc atctaaataa gatactttcc catatcttga attttttgat ttaaagctat
    38401 ttgatatatt cgttatatat tcttttgcat cttcagctaa cccagtattt aatagagaat
    38461 atactacttg taaatgtttt aaatagtcat gtttttgact tcttaatttt acgattatat
    38521 tgtccttatg atttatttta ctgtctaatt tttgtagctt atactcttgt ttattgttat
    38581 tgtctagtaa tcttataaat ttaaatccta tataaaagct taaaataatt aaaattaaaa
    38641 aaagtataat atttaatact ccttcaagta aaaaattata tcctaaactt aattgtatat
    38701 actcaatacc ctccatgaat aaaatccata caaaacacga tacaaaaaac gttaatattc
    38761 ctctttttaa tatgtctaat tctttataaa acctgtattt attcattata agattactaa
    38821 atataaacaa agttagtatt actataggaa atataaaatt attctccata attcccctcc
    38881 catctacact ttatatgagg attatatcat tttagaaaaa ttatgtaaaa agtcaaaatt
    38941 tacatgtaca ttaattaaac ttgcaaatac acatataaat ttgtacaatt aagtactcaa
    39001 aacttgaaga tacttacttt gatatatatt ttaaataaac atataattga tttagctaag
    39061 aaaggaagtg gtaaatatga aagataattt aaaaatagca ctaagataca taataagtta
    39121 taaagcaagg tctttagcaa ttgctctaag tataattctt gctacatcac ttattgttgg
    39181 tattggtacc ctctcaagaa gtgctcaaca agcagaggta gataaattaa aaagagaaac
    39241 tggaagtgat catgtatact ttaaagatat aaataaaaat caattagaat acataaagtc
    39301 tagaaaagat attaaaaatt taggtataac atctcactat ggctatacag atcctaatga
    39361 aagattagct ataaacctag aatatgcaaa taaaaattac ttgactaatc aatccaaact
    39421 tataaaaggt caccttccaa aagctagtaa tgaggtggtc gtagagaaat ggattttaaa
    39481 tagtctgggt ttaaaaccag aaataaatca gaacattact tttaaattat atcaaaaaga
    39541 aaaaccagag acatttaaag ttgtaggaat acttgaagat agacctattg agaaaaataa
    39601 agggacatgt gaaatttttt taaatctcaa tgaatcaaaa ttggataaat tttcttatgc
    39661 ttatattgaa tttaataatg gcattgatat aaatacaagc atagataata tagtaaaaaa
    39721 tactatgttg gatgagaata gtgttggaaa aaacaaaatg cttatagaat ctactaggga
    39781 aaatggtact ttagataact caagtaaata cactgcaatt actatgagcc tattttctgg
    39841 tattgtaata tatagtatct atgttatatc gatatatcaa agaatacagg aatatggtat
    39901 cttaagagct attggatcca ctaacttcaa gattttcaag tttatgtttt atgaactttt
    39961 catacttgct ttgatagcaa tacctatcgg tatatgcaca ggtattggtg gtgcacaaat
    40021 atttaatagg actgcaggaa atattcaatt tgaaggtaat gtaacagtta ccccttttgt
    40081 tattccagat aaaataatac ttttatcaat tggaagtata atactgacaa tactaattat
    40141 aagtttcttt acatatttaa agataagaag aatttctcct attgactcta taagaaaaac
    40201 ctttggaact gataaaaata taaataaggt caattctttg atatcaaaat taactttaaa
    40261 tatatcagta acaaaatcta tatctgctaa aaatatcttt aggaataaaa agggcttcat
    40321 tataattata ttatccatga gtctaggagg tataatgatc ataaaggaga attataaata
    40381 ttctttttca gatatacaaa ataaaaatgg tcaagaagaa acatatatga atgcagattt
    40441 tattctaaca aattttttct taaaactaaa tcaatctaat aaagctgatt ctttcaagga
    40501 tataaaagga cttaatgata atcagataga taaaataaaa aatataaatg gaattgacaa
    40561 agtcaaaact gccagcatct tagatacaag aatagaagta gataaattaa atggattaga
    40621 ttactacaat attattaatt caacgcctta ttataaggat tttcctctat tcataaaaaa
    40681 taagaatact ggaaaatata caatgaaaca aaagttaaga ggttacaatg atgagatgat
    40741 aaattcatta gaaaaatact tagtgagtgg gagtataaat ctggaaagaa tgaaaaaaga
    40801 aaacctcgct atattatacg taccacaagt ttctaaaaca aataaataca agctaagtta
    40861 tactcctggt acagaaacgc ctgctgtaga tataaaagta ggagatacta taaaggtcaa
    40921 atatccaaaa ggtgagatag atcaagatct ttatataaaa ctaaaagata attatgaata
    40981 tctagaatat gagtttaaag ttggagctat tgtaagttat ccttttgcag ataattacct
    41041 atattctgga gatcagggta tagatgtaat aacaagtaac gactatctaa aaaaactaac
    41101 tggtgtagat aaatataatg tagtttatgt agatattaat aaaaatgcaa atgtaaaaaa
    41161 gataaataca ctcttaggtg aaataggaag tgaatctcct ggaactacaa cagctaatat
    41221 gctaatggaa aaagaaaact ttgataagat gacagctagg gctctgactt atgcttatgg
    41281 aatagtagca gtaatgttta taattagtgt gtttaatata ataaataaca taagttataa
    41341 cttaacttca agaactagcg aatttggaat gttaagagct attggtatct ctgagagagg
    41401 atttaaaaat atgatactct atgagggaat attatatgga atactctcaa gtgtaattac
    41461 cattgtggta gggcttataa tacagtttag aatgtattac acgtataatt ttgtatcata
    41521 tggattggga ttttcaatag attacaaaat atatatccta gttgttttag caaacataat
    41581 tgtaggtatt ctagctacat atattccatt aaggaaaata aataaaatta gtatagttga
    41641 agctataaac attacagaat aggaggatta attatgccta tattagagat tcttaactta
    41701 ggtaagattt atggaaaaaa ggaaacagct gtacatgcac taaaggatgc aaatttaaaa
    41761 ataaataagg gtgaatttgt tgcgataatt ggcccaagtg gaagtggaaa aagcacattt
    41821 ctacatttag taggaggtct tgagagacca agtagtggaa ctataaaagt cgatggtaaa
    41881 gatatatgtt gcctttcaga taaaaaatta gcaaaatata gaagacaaaa agtaggcttt
    41941 gtttttcaac agtataacct aattccagta ttaaatgtaa aagaaaatat agaattacca
    42001 ctaaagttag acaataaaaa agttgatgaa gaatacatcg aagacattat aaatttattg
    42061 ggtcttagtg agaggaaaaa tcatcttcca aatcaattat ctggtggtca acaacaaagg
    42121 gttgctattg cacgcgcttt atctgcaaaa ccaagtataa tcctagcaga tgaaccaaca
    42181 ggaaatttgg atagtaaaac tacggaagaa gtcatggatt tactaaaaag ttctataaaa
    42241 aaatataacc aaacacttat aataataaca cataatgaaa atattgctag aaaagcagat
    42301 agaattatat ctataataga tggagagctt aaattaacac tctaaaacta tttatagaaa
    42361 agaggattta aatgttattg attttagata atttaaattt aaacttagat tttgactaca
    42421 gaataataag agaagaaaat gatgatgtag atatatttat agatattaat tatcgtagct
    42481 tagatataga tactgatggt tctaacttat ttaattctag aatacaattt ccatttgtaa
    42541 gagcattgat tctaaggata aataagaaca atcaatgtat gacaattcat ttgttaagag
    42601 atatagattt attctctgct tttgccaact ttgaagtgga ttatactgac tctataataa
    42661 atataaaaaa tcaaaatgag aaagtaattt taaataaatc tatcaaaaaa tagtaagggg
    42721 gccttaatag gccccaattt ttttcttttc taaatttatt atatcatgat aaataaatta
    42781 gtcaatagaa ttttctgaat atttttataa ttttttcata aagtttttta tatattatgc
    42841 tttaaaatta tatgtaataa aaaaattttc cgactaattt taaagttaat tgattaaata
    42901 cacatattcg aaattaccat taaattactg actttttatc atttccattc agaatttaag
    42961 ttataatcta ttatttatag ttacttctac gtttctctaa taaaactcta tttatattca
    43021 aatctaataa tttatataca aacccaatag aacctatgtt gtacaatgaa tattatttac
    43081 cataataaac ttttagatat atctctttta attcactcat caatgggtat ctaggattag
    43141 cacctgtaca ttggtcatca aaagcttgtt caaccataac atccaatgtt tctaagaatt
    43201 tagattcttc tactccagcc tcttttatag ttttaggaag tcctactctt gcctttaatt
    43261 catctattgc ttttataagg ttatctactt tttcttggtc tgtatttccc ttgattcctg
    43321 caaaagaagc aaattcagca tatctttgta tacaatcagg atatctgtat tgtgagaatg
    43381 cacccatctt atttggagct tctgcacaat tgaacttaat tacttcattt attaataatg
    43441 catttgcaac accgtgttga acatggtgga atgcacctaa tttatgtgct aaagagtgac
    43501 atattcctaa gaaggcattt gcaaaagaca ttcctgccat agtagatgcc attgccattt
    43561 tttctcttgc ttctttatca ttctttccat ttttgtatgc acgaggtaga tattcaaata
    43621 ttattttacc tgcttgtagt gctagaccgt cagctggttc agttcttaac atagatacat
    43681 atgcttctaa tgcatgtgtt aaagcatcaa cacctgatgc tgctgttaat cttggtggca
    43741 tctccatcat catatcagca tcaattatag ccatgtttgg cattaattca taatctgcta
    43801 atgggtactt tacacctgaa tcttggtcag ttataactgc aaatggagtt acttctgaac
    43861 cagttcctgc tgaagttggg atagcagcaa aatacgcttt ttcacccatc ttaggaaata
    43921 catatactct ttttcttata tccataaatc tcatagccaa atcttggaag tctacctctg
    43981 gatgctcata cattacccac attatcttac cagcatccat tgcgctacct ccacctacag
    44041 ctattattaa atctggttgg aaatcagcca tagccttagc tccttctctt gcacaagcta
    44101 atgttgggtc tggagcaaca tcaaagaatg tagtatgctt aattcccatc tcatccaaca
    44161 aatcagttag cttcttagtg tatccattat tgtaaaggaa agaatctgtt actataaagg
    44221 ctttcttttt atccataaca tctttaaatt ctcttgctgc tacacctaaa caaccttttt
    44281 tgaaataaac cttttctggt gctctaaacc aaagcatatt ctctctcctt tcagctactg
    44341 tcttgatatt aagtaaatgt ttcactccca cgttttcaga tactgagttt ccaccccaag
    44401 aaccacaacc aagagtaaga gatggtgcta atttaaagtt atataagtca cctataccac
    44461 cttgtgacga tggagtatta actaatactc tacaagtttt catagcattt acaaacttct
    44521 ctactctatc tggatgattt atagagtctg catataacga agatgtatgg ccatatccac
    44581 catctgcaac taatttttca gctttagcaa ctgcatcttc aaaactttta gatttgtaca
    44641 ttgcaagtac aggagaaagt ttttcatgtg caaaaggttc atttaattca acagattcta
    44701 cttcaccaat tattattcta gctgtttttg gaacttctac atccgccatt ttggctatta
    44761 catgtgctgg ttgtccaact attctggcat ttaatgaacc atcaattatt actacttttc
    44821 ctactttttc agtttcttct ttatttagga aatgtgctcc acggtattta aattcttttt
    44881 taacttcttc atatattttt tctggtacta ttacagcttg ctcggaagca catatcatac
    44941 cattatcgaa tgattttgat actaagattg aacttacagc catttttata tctgcactct
    45001 catctattat tgcaggtaca tttccaggcc caactccaac agctggttta cctgaagagt
    45061 atgcagattt aaccattcca ggtccaccag tagctaatat aaggtctgcc tctgccatga
    45121 caacattagt taattcaatc gaaggaacat ctacccaacc tataagtcct tttggtgctc
    45181 ctgccttaac tgccgcatca tgtacaactc tagctgcttc tatagtacag tttttagctc
    45241 ttggatgagg agagaaaatt ataccatttc tagtttttag tgctattagg gatttgaata
    45301 ttgcagttga tgtaggatta gttgttggta taactgctga taaaacacct actggctcag
    45361 caattcttgt aaaaccaaat gcttcatctt tttctatgac accacaagtt ttagtatctt
    45421 tataagcatt atagatatat tctgaggcaa aatggttttt tataacctta tcttcaacaa
    45481 tacccatacc agtctcttcc actgccattt ttgctagagg tattctttgt tgattagctg
    45541 cagttgaagc agctaagaaa atcttatcta cctgttcttg cgtaaatgtt gcaaattctt
    45601 tttgtgccaa tctaatttct tctaatctca ttcttaatgt ttcaacactg ttgacaattt
    45661 caggactaca tacttcaaca tttgattttt ctactacctt ttcttttttc tccatactaa
    45721 aaacctccct aaaataatta tgcatctcta atttttataa atcttaaatg caccatctat
    45781 atttttaact tatacttaaa ataattttat agatttcatc tctatacctt agattttatt
    45841 tattttactc tcttaggtca agaagttttt ttctgaatat tttgtcaatt tattttttaa
    45901 caaatatatt atttttttta cttttactaa aattttttat ctaaatgaga tatatttcat
    45961 ttgaataatt tacttca
//
LOCUS       DAMJWO010000024        45646 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.025, whole genome shotgun sequence.
ACCESSION   DAMJWO010000024 DAMJWO010000000
VERSION     DAMJWO010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45646
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.025"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            137..520
                     /locus_tag="PC366_001370"
     CDS             137..520
                     /locus_tag="PC366_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF2576902.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLEDKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            522..872
                     /locus_tag="PC366_001371"
     CDS             522..872
                     /locus_tag="PC366_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576903.1"
                     /translation="MDNTITINISIIYVLLAILACIALVYLIIVLVKLHKILNNVGTM
                     LNENTQNINTTLNNLPNVVETFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFLDKK"
     gene            complement(966..1424)
                     /locus_tag="PC366_001372"
     CDS             complement(966..1424)
                     /locus_tag="PC366_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576904.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSSGRADFLYSSRLQKLLNEVYINQSRASYISGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(1469..2257)
                     /locus_tag="PC366_001373"
     CDS             complement(1469..2257)
                     /locus_tag="PC366_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2576905.1"
                     /translation="MKVVIIPGHTLIGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNATTSTPVGTETIYKTNNGKTY
                     AERVNTRLATVFKDRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQGGGENKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALQEIDKL"
     gene            complement(2396..2833)
                     /locus_tag="PC366_001374"
     CDS             complement(2396..2833)
                     /locus_tag="PC366_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HDF2576906.1"
                     /translation="MNKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKDCSIYVTHF
                     PCLNCTKAIIQAGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            3655..4164
                     /locus_tag="PC366_001375"
     CDS             3655..4164
                     /locus_tag="PC366_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2576907.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVESEVDSLKVISEKLEIINLQLAQRKNMRRKMFHWLF
                     ILLCAVIVIVFVVLGGLNSPYLDWNYTDPETAVFGVAFHAFEWLFVRLVPIVLIGAII
                     GIFLTRKKI"
     gene            complement(5075..5875)
                     /locus_tag="PC366_001376"
     CDS             complement(5075..5875)
                     /locus_tag="PC366_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2576908.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYAFSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGATKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(6070..7668)
                     /locus_tag="PC366_001377"
     CDS             complement(6070..7668)
                     /locus_tag="PC366_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2576909.1"
                     /translation="MKAAIYSRKSRFTGKGDSIENQIQLCIDYAKSIGVKDFLIYEDE
                     GFSGSNIDRPQFKKMMQDAKDKKFSYLVCYRLDRISRNVSDFSTLIEKLNELNISFIS
                     IKEQFDTSTPMGRAMMFISSVFAQLERETIAERIKDNMYELARSGRWLGGNTPHGFNS
                     EKITFLDENLKERSMYKLQVNDEQMEIVKLIYNKYLELRSLSKLYKYVYNNGIRGPRG
                     GKFDPSSLSRILRNPAYVKANDEILDYLKNSGMDVVGTPDRKCGILTYAKNTSNSIAA
                     IAKHHGVIEPEIWLEVQNQLDKNRDKTPRISTGKTALLSGLIKCGKCGSNMRITYKGK
                     KTDKDLKYYYICGTKKTLGSDSCNCKNLNGPLVESLVIDKIKNCKEESIISAFNSNNI
                     KTDNVFNIFKSETNLLKNQILDKERLIKNLVIELAKNTGSTASDYIVSQIESLNNEIS
                     ILKDKINILESSNINISSDSINIDIIVSNLKRFNDEVDNASLDDKRLLLSTIINSIIW
                     DSSLGNLNIVYMGAEVDNSVSLSN"
     gene            7996..8172
                     /locus_tag="PC366_001378"
     CDS             7996..8172
                     /locus_tag="PC366_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576910.1"
                     /translation="MEINVIEIFPKDKAKLNKIEMDKASWFVNIISKKYPKEALNEAF
                     SILEKELNISKANT"
     gene            8346..9476
                     /locus_tag="PC366_001379"
     CDS             8346..9476
                     /locus_tag="PC366_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF2576911.1"
                     /translation="MNNFEIKTRIKFGEGSLKVLQELKNKNVLIITDPFMVKSKTIDK
                     ITSNLINSTYQVFEEIVPDPPIEVVVAGIEAFKSINPDVIIALGGGSAIDAAKSIMDF
                     SKKILKINEVEFIAIPTTSGTGSEVTSFAVITDSQKKCKYPLVSDDLLPDMAILDPEL
                     VKTVPNFITADTGMDVLTHAIEAYVSTNSNDFSDALAEKSIKLVFKYLIKAYKDGNDI
                     EAREKMHNASCLAGMAFNQASLGINHSIAHVLGGKFHIPHGRTNSILLPHVIEYNSSI
                     VGYTNTTYSDTAKKYAQIAELVGLGSANIRISVRNLVNEIKKLQKEMNMPTKLTQCKL
                     SLEDITNEEREIAKLAIKDTCTLTNPKVPTEDDIINILNNIK"
     gene            9717..10067
                     /locus_tag="PC366_001380"
     CDS             9717..10067
                     /locus_tag="PC366_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003453843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HDF2576912.1"
                     /translation="MTEESKQRVIQEYVPGKQVTLAHIIANPNEDIYKKLGLVLDKRD
                     AIGILTITPSEASIIAADVATKASNVSLGFIDRFSGSVVISGDVSSVESALNDVLEVL
                     GNMLNFSSTKITRT"
     gene            10075..10524
                     /locus_tag="PC366_001381"
     CDS             10075..10524
                     /locus_tag="PC366_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HDF2576913.1"
                     /translation="MKNIIFMGKTGSGKTTLCQKLDQLELKYKKTQSVELYNNAIDTP
                     GEYMENRNLYNALITTSADAKIIAIVYDATQEENYIAPGFASMFCKDVIGIITKINKA
                     TENEVNIAYERLSLAGASQIFKIDTVDDIGLEKLFKYLEKSKNIDEV"
     gene            10626..11201
                     /locus_tag="PC366_001382"
     CDS             10626..11201
                     /locus_tag="PC366_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDF2576914.1"
                     /translation="MGKKILLVDDEPLLRMDTKDILESHGYEIIGEASDGFEAVEMCK
                     KHKPDLVIMDIEMPILDGIKAGKIICKENLAGGVLLLTSFEDKEYVEKAKSIGAYGYL
                     VKTASEKSLIPTIEMCLNKVNEFEKMKKDLEKVNSKLNERKLVERAKGILIREFKISE
                     DEAYTRIRKLSMDKRTTMMEIAKMIIIGYDD"
     gene            11194..12603
                     /locus_tag="PC366_001383"
     CDS             11194..12603
                     /locus_tag="PC366_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal domain-containing
                     protein"
                     /protein_id="HDF2576915.1"
                     /translation="MTNTIKKISTAQTYLNNNEIEKIIEVSKSLDLMASFYEADVFID
                     VLSKFDDEAIVVAHGRPKEKSMYCENVIGKKALIENEPGVIKCLKTGERVRDIKALTQ
                     EYKLVKQNIQPITLDDKVLAVLIVEKDISSEVKNEFNASEDEENKNLHQFIKLIGNND
                     FLVDNLNSAILIFDKNGKLKIKNRIATEIYKNLGFGYDIQDMHYNDLDIETNTFENIL
                     MDENYDETNEVSIGNMFFKIKTIYIKDDEFKVCKIVQDISDLKRKEEELVLKTVAIRE
                     AHHRVKNNLHTVISIIKKQSRLSQNDEVKQCLDNIINRVFAILSTHYLLSKEVDNNIS
                     IREGINLLVSNIQGGYLFSKDIDIRITGEDFKISGEKATAILLVINEILQNCYDHAFS
                     DREHGTIQILINKDNDYRNIAIIDDGIGFDSNNINKNSLGTYIIDSYITQMLKGNIER
                     KSNENGTEVLITIPTQINI"
     gene            12787..14220
                     /gene="eutA"
                     /locus_tag="PC366_001384"
     CDS             12787..14220
                     /gene="eutA"
                     /locus_tag="PC366_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004458698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HDF2576916.1"
                     /translation="MREELLSVGIDIGTSTTQLIFSKLIVENTESNFSVPRISIVDKE
                     IIYKSKVYFTPLISNNEINGQQIKDIVENEYKKANISKEDIHTGAVIITGETARKENA
                     NDVLHTLSGFAGDFVVATAGPDLESIISGKGAGAHIYSKEHSTTIVNIDIGGGTSNIA
                     SFKRGEVTDTGCLDIGGRLVKIDKISKKITYISPKIDKIIKDNNLNLQVGTMATVENT
                     KPIVDIMVDLLMESIGLKKQTPLFDFIITNKSISIDENIKNVSFSGGVADYIYYDGEI
                     KDYFEYGDLGILLGQTIKNCEYLKKVNVVKSMETIRATVVGAGSHTTEVSGSTITYTS
                     EKFPLKNLPVLKLSVDEETGTSKQISEAIKNKLNWFKLENDLQKVAIAMIGKKNPTFL
                     DIQEYAKGFVDGMQQIIENDLPFIVIVENDMAKVLGQAIYALLNYEKEIVCIDSVKVE
                     NGDYIDIGKPIVEGKVLPVVIKTLVFN"
     gene            14238..15602
                     /locus_tag="PC366_001385"
     CDS             14238..15602
                     /locus_tag="PC366_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HDF2576917.1"
                     /translation="MILNTKLFGRTYQFKGLYDVMAKANEEKSGDKLAGLAAESAEER
                     IAAKVVLSHIKLEDIRNNPAVAYEEDEVTRIIQDAVNEKVYEEIKNWTVSELREWLLD
                     SNTTSLDIRRISRGLTSEMIAAVAKLMSNMDLVYAAKKIKVTAHCNTTIGEQGTLSAR
                     LQPNHPTDDPDGILASLLEGLTFGIGDAVLGLNPVDDSVESVTKVLKRFEEVKQKYQI
                     PTQTCVLAHVTTQMEAIRNGAPADLIFQSIAGSEKGNEAFGFNGDTIEEARQLALKHG
                     TATGPNVMYFETGQGSELSSEAHHGIDQVTMEARCYGFAKKYEPFLVNTVVGFIGPEY
                     LYDAREVVRAGLEDHFMGKLHGLPMGVDVCYTNHMKADQNDMENLAILLTTAGCTYFM
                     GIPHGDDVMLNYQTTGYHETASLREMFGLTAIKEFDAWMEKMGFYKDGKLTELAGDAS
                     VLLG"
     gene            15615..16496
                     /gene="eutC"
                     /locus_tag="PC366_001386"
     CDS             15615..16496
                     /gene="eutC"
                     /locus_tag="PC366_001386"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014952556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HDF2576918.1"
                     /translation="MNEKDLKALVEQLVGQMVGELDTNVVSETVKKTTEVVVDNNAFI
                     DDITEVDIRKQLLVKNPKDAEAYLDMKAKTPARLGIGRAGTRYKTETVLRFRADHAAA
                     QDAVFSYVDEEFIKENNMFAVETLCKDKDEYLTRPDLGRKFSQETINNIKSKFGTNQK
                     VLILVGDGLSSAAIEANLKDCVPAIKQGLKMYGIDSSEILFVKHCRVGAMDHLGEELG
                     CEVICMLVGERPGLVTAESMSAYIAYKPYIGMAEAKRTVISNIHKGGTTAVEAGAHIA
                     ELIKTMLDKKASGIDLK"
     gene            16516..17169
                     /gene="eutL"
                     /locus_tag="PC366_001387"
     CDS             16516..17169
                     /gene="eutL"
                     /locus_tag="PC366_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003761789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HDF2576919.1"
                     /translation="MKNDVIRPNILGIKIISNISPEMAQKLELKSHHKSLGLITADCD
                     DVTYTALDEATKASEVDVVYAKSMYAGAANASTKLAGEVLGIIAGPSPAEVRSGLNAV
                     VDFLEYGATFISANDDDSIAYYAHCVSRTGTYLSEIAGIREGEALAYLVAPPLEAMYA
                     LDAAMKAADVKMCELFAPPTETNFGGALLTGSQSACKAACDAFAEAVKSVADNPTGF"
     gene            17180..17881
                     /locus_tag="PC366_001388"
     CDS             17180..17881
                     /locus_tag="PC366_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HDF2576920.1"
                     /translation="MDAIGLIEVIGYVAAIEASDACLKSANVNIVRIDKVGAGIVTLT
                     ICGDVGAVKAALEAGEIAASRVGTLRTSHIIPRIHNEVTNALFKTKEPKVCEVSEDKE
                     KNFEITLEITDNVSKNLSEKENVILDVNENSGDTENLYSDIDKTNKKIETVDDSLTEA
                     NEEKIENTNDKEVLEQVKIENSDFDRDDLSKNSVKKLKAMAKKLDSSITYKDLNVLKK
                     EELINLVKKLSRRDR"
     gene            17884..19353
                     /locus_tag="PC366_001389"
     CDS             17884..19353
                     /locus_tag="PC366_001389"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HDF2576921.1"
                     /translation="MTLLDKDLVSIQEVRTLVRRSKVAQEKLSKMSQEQIDKIVKAVV
                     DAAFNNATKLAKMANEETGFGKWEDKVIKNTFASMGVYETLKNTKTIGIIGEDKEANT
                     IDIATPVGVVAGLIPSTNPTSTVIYKTIISLKAGNTIVFSPHPNAKNCILETVNIISE
                     AAIKAGAPEDSILCITNPSIVGTNELMKHKDTNLILATGGEAMVRAAYSSGTPAIGVG
                     PGNGPAFIDKSANVKLAIKRIIDSKTFDNGVICASEQSIVIEKSMEETVLKELKNQGA
                     YVLNEEESERLAKFILRANGTMNPQIVGKSVEVIANLADLTNIPKNTKVLVARENKVG
                     HNVAYSREKLTPILAFYVEENVEAIMNRCREILLNEGAGHTFSMHVNDEELVKRFALN
                     MPVSRILVNTPSALGGIGASTNLVPALTLGCGAIGGSSTSNNIGPLDLINVKRVAYGI
                     KEIEELGRDKSQVEKSMFDSMDKEELINLLVQKLVKELA"
     gene            19449..19736
                     /gene="eutM"
                     /locus_tag="PC366_001390"
     CDS             19449..19736
                     /gene="eutM"
                     /locus_tag="PC366_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HDF2576922.1"
                     /translation="MASANALGMIETKGLVGAIEAADAMVKAANVQLVGKEQVGGGLV
                     TVMVRGDVGAVKAATDAGAAAAERVGELISVHVIPRPHFEVDAILPKVSAE"
     gene            19863..20624
                     /locus_tag="PC366_001391"
     CDS             19863..20624
                     /locus_tag="PC366_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin adenosyltransferase"
                     /protein_id="HDF2576923.1"
                     /translation="MGVLTENEVKRKIGKNKNNITEFYIEKGQIITPSAKSYLAERSI
                     ELKYVDKLSDVNNEPKEVVKEVVKEKKYKYTTVFGAKLDEKPEHMTQLNGNLLVFKDH
                     KRIILRGKIDSLESEILKVQILCQKLDMPKLVKELQEVLDFVRNIMRCEVLDEKLEDF
                     KLLGLTPQELREQSHYPKKYFGIGHEFPSYEMGEVVVAINSIRSNTREVELAAYEAFK
                     GEYGNVHREDLIKALNRLSSVFWIMIYKVRTNKYK"
     gene            20637..21266
                     /locus_tag="PC366_001392"
     CDS             20637..21266
                     /locus_tag="PC366_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HDF2576924.1"
                     /translation="MENLLNEIVEEVITRVKKEAFIEVEASGRHVHLSREDVDKLFGE
                     GYTLTKLKDLSQPGQYACKERVTITGPKGSIKNVVVLGPCRNETQVEISLTDGSTLGL
                     KAPIKQSGDLEGTLSIKISTQYGEVELDKGLMVAKRHIHMTPKDAEKFNVCDKEIVEA
                     KVMGQRPLTFDDVVIRVSDSFKTYMHIDYDEANACGYSKGTVAKIIKKA"
     gene            21308..22033
                     /locus_tag="PC366_001393"
     CDS             21308..22033
                     /locus_tag="PC366_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02536 family ethanolamine utilization
                     protein"
                     /protein_id="HDF2576925.1"
                     /translation="MNYDNLVDLITEEIYKKINSNEIKISNKPKAVIVFEQDNNKFNL
                     LKDEFEILEFDKSIRECEIVIVSRLCMRGLSNIALGNSTSDEERFILKMIMKGKKVYV
                     LDEGIEYKKYKDTAPKALYKKFMSFEDEICKFGVEIIKDLNVITKNKLNIKKELESTR
                     GSKKEDTKVLDKDVLNLTSVESVKIDNEFSLDLRNKKLISEADLRKPTINGVKNILVN
                     KKSIITPLAVDFMRIHHLKLKKL"
     gene            22046..22318
                     /locus_tag="PC366_001394"
     CDS             22046..22318
                     /locus_tag="PC366_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HDF2576926.1"
                     /translation="MDIGKVVGNVWATRKDEKLCGQKLLVVKILKTKDTYKEGFMVAA
                     DNAGAGNGDLVLISKGSSARESIEKSHVPVDATIVGVVDSFEVFDE"
     gene            22311..22862
                     /locus_tag="PC366_001395"
     CDS             22311..22862
                     /locus_tag="PC366_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HDF2576927.1"
                     /translation="MNKSIGAIEFKSIAKGIEVSNEMIKKSSVDVLYLKSICPGKFLI
                     IVGGETSYINECVDYGIKLGEGYIVDNFVINAISQEILDGFKNKYQKLDSIVSIGVVE
                     SSKVCAGIKMLDKTLKSGDLVLVKLQLSFAIGGKLVYVVAGDLSSLEYALKESENVVR
                     EKEVIYKTVIPSVDSQIIKSLIK"
     gene            22874..23965
                     /gene="eutH"
                     /locus_tag="PC366_001396"
     CDS             22874..23965
                     /gene="eutH"
                     /locus_tag="PC366_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HDF2576928.1"
                     /translation="MSINEIIIYVMVVFMVLGAIDKCIGNKFGLGEQFEEGIMAMGSL
                     AVAMVGVICLAPVLADVLRPIVVPVFNILGADPAMFAGSLLANDMGGAPLALELAKDP
                     NSGLFGGLIVGAMMGPTIVFIIPVALGIIEKEDQKFLATGILAGIITIPIGAFVGGLV
                     AGFEVMMVLRNLVPIIIFAVVIALGLLKFENAMIKGFTYFGKGVVIVITLGLAAAIVE
                     ALTGIVVIPGMKPISEGIEIVGDIAIVLAGAFPLVFVITKVFNKPLMALGKVLGMNDV
                     SAAGLVASLANCIPMFGMMKDMDNRGKIINVAFSVSAAFVFGDHLGFTAGFNSNMITP
                     MIVAKLVGGITAVLLAMVIANKTLRKENV"
     gene            23967..24440
                     /locus_tag="PC366_001397"
     CDS             23967..24440
                     /locus_tag="PC366_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF861 domain-containing protein"
                     /protein_id="HDF2576929.1"
                     /translation="MDISNIDKNLIETLVRQIIEEKISGTKDTVDFVRNKDISGITSI
                     KLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEID
                     YVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN"
     gene            complement(24560..24661)
                     /locus_tag="PC366_001398"
                     /pseudo
     CDS             complement(24560..24661)
                     /locus_tag="PC366_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433047.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
     gene            24956..25477
                     /locus_tag="PC366_001399"
     CDS             24956..25477
                     /locus_tag="PC366_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2576930.1"
                     /translation="MEEIVKKEQASMNDIFLYLKAKSNSLYKFVILYNEFINKPKDYG
                     TGELINMVEVHMLTAIEENPGISPTQLAKIWNRTKGAISQTISKLEKKGYITKEKKEG
                     NAKTILLYPTTSGVELSKAHKLYDTIDVTRTFEYLIKECTLEEIDSFYKVIDLFINLL
                     EESPQENNDSEKV"
     gene            25856..27031
                     /locus_tag="PC366_001400"
     CDS             25856..27031
                     /locus_tag="PC366_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2576931.1"
                     /translation="MNLKQLSEKYEEYVIQMRREFHKYPELSFKEIRTTQRIREELQK
                     IGVPFVSIEPNIVIATIQGKNEGKTIAIRGDIDALPMQEDSDVEYKSEYDGIMHSCGH
                     DAHGAMLLGLAHMLNDIRKDLKGRVLLVFQAAEEVGGGHKEIIQYFKENGGPDRLIAT
                     HVWSDIEAGKISVEPGPRMAGGSGWRIDITGRGGHGSRPDQSIDPIKPACDIVLKVSS
                     IPVNHISVLEQCVVHACAIHGGTTIGNVIPNNAEVIGGYRYFTEESGKKVFDIIKQMS
                     NGVGQAYGVDVKVTHTGGIGPVINDEEAVKMAKEIVSNIDGLELDSYEPICASDCYGE
                     ILKEYSGFYCYLGVGNKEKGIIYAQHHPKYNIDEDTLKLGCEFMAKYAVEFLNKNNN"
     gene            27066..28604
                     /locus_tag="PC366_001401"
     CDS             27066..28604
                     /locus_tag="PC366_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HDF2576932.1"
                     /translation="MQGALKENKKKSGGGFLGWIERVGNKMPHPLALFTYITLIVVAL
                     SAIASFLGFSATSPATGKLIKVMNLISAKGLVLFMQEFVKNFQNFPVLGVVLVMAVAT
                     GVCEKTGFFSTAIKMSLSKVKGNAVVFIIAFIGVFANQAGDAAFVLVPTLAGAIFYGL
                     NRNPLAGIFCGFASVGGGFATAVIPGGWDVTLTPITVSAAQTIQPAFDMTLLASYYAL
                     FVSAFIVATVSTIVTVKFIEPKLGKYTGKPEGIDDNQGFEVTKEQAKAAKLAGFTVLA
                     YVALLIALCIPANSFLRSPEGSLIFGAPLMSCLQFFIVILFFLPGIVYGMRVGKIKTV
                     KDLNDILCQSMAAMAPFIVLAIVIGQFLTLFSVSNLAQVLAIKGGALLNSLPLPPQVI
                     ILLFLVLVAFINIFVISGSTKWMIFGPVFVPMLMQLNIHPAFTQFVYRLGDSVTNHLS
                     PLNAFFIILLATVQKYDKNAGMGTIFSAMIPYTIGYFVVLAVLVVVWMTIGIPVGIGG
                     QVWL"
     gene            28636..29838
                     /locus_tag="PC366_001402"
     CDS             28636..29838
                     /locus_tag="PC366_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2576933.1"
                     /translation="METTEIRYNFDEVIDRSGTNCLKYDLKSQFMPESPEDALPLWVA
                     DMDFACAPEIINAMHERIDRKIFGYSSQQTDDYYEAVCGWFKRRFDWKIEKENIFFSP
                     GVVPALGFFIQILTQKGDGIIIEKPVYYPFEDKITNNERKVVNSPLKFEDGHYSMDYD
                     GFEELAKDENNKVFILCSPHNPVGRVWKKEELRKIVDICKKYDLWIISDEIHCDIIRK
                     SEKHIPLEVACPDYKDRIITCTAPSKSFNLAGMQLSNIVINNKELQEKWMLETDSKLA
                     IFLPNPFAIVATKVAYNDCEDWMNQVNEYIDGNIKYVEDFVNEYMPKVKIIKSQGTYL
                     IWLDFRGYGLDAKQLEYVMLNKAKVLLDEGYIFGEEGAGFERINVASPRTIIEECMNR
                     IKCAFEGL"
     gene            complement(30017..30616)
                     /locus_tag="PC366_001403"
     CDS             complement(30017..30616)
                     /locus_tag="PC366_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2576934.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGEARCIKVQL"
     gene            30785..32143
                     /locus_tag="PC366_001404"
     CDS             30785..32143
                     /locus_tag="PC366_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576935.1"
                     /translation="MSNIITNLIESVFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKVRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERMDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEALKSLLEGSQSSIKTFDQSVRKLDKQFNILNI
                     KFVKLFDKYDNQDNINKEILFDIKESSKNIYNATESQFKIRDYIKNINAGFALYERSA
                     QDLLTKLMTHENKISQNQKILLDEKFTLDDSIKNLSSIIENFSNDLQVKLDMMFENSL
                     DIQDKLDVMFNNSFMNDEVPLDSEELFKDDVNNVFNPFSEEIYEIEDKEIKVIGEDEL
                     NE"
     gene            32136..32768
                     /locus_tag="PC366_001405"
     CDS             32136..32768
                     /locus_tag="PC366_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDF2576936.1"
                     /translation="MNNKYRRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNASVEETFKKSKIPVKVDKSNGQVTFGEKTMFDVDSDVLKPEAKEML
                     KMFVPKYIETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            33097..34254
                     /locus_tag="PC366_001406"
     CDS             33097..34254
                     /locus_tag="PC366_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2576937.1"
                     /translation="MIEISIKNKKNSKIKTLILLLIVSISIYLTGCTTSDNGNNQSNN
                     NDSLSSSISSDKNVKIHFIDTGNSDAILIQDGKTFTLIDGGDNDDEGLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALANKGLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILP
                     KLEKVDLLKVAHHGSRSSSSQEFLDKVNPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNSNTSKNDSFKNKQNT
                     FNSEEIVYFTPKGKSYHSIKNCSGLSRSKKILSGTIEESKKNDPCDICYGK"
     gene            complement(34402..35037)
                     /gene="lexA"
                     /locus_tag="PC366_001407"
     CDS             complement(34402..35037)
                     /gene="lexA"
                     /locus_tag="PC366_001407"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HDF2576938.1"
                     /translation="MYLDLTEKQVLILEFIKSQITLKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLRVKGESMINAGILDEDYVVVDKKNTALNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(35141..36268)
                     /locus_tag="PC366_001408"
     CDS             complement(35141..36268)
                     /locus_tag="PC366_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2576939.1"
                     /translation="MNNDKKIIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNADCVKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRDNGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
     gene            complement(36590..37435)
                     /locus_tag="PC366_001409"
     CDS             complement(36590..37435)
                     /locus_tag="PC366_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576940.1"
                     /translation="MIYIIEILKISVINIFCFIGIFIVFGLIFSITENLNNKFIFSSF
                     GKTGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTIMIILIFKILLPDSYMKVTQNIDLKLYVSMINNLNING
                     FIHIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFVISSITYLFGFDNLNISSLIVKYNIFISFFMAIGFIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            complement(37465..37836)
                     /locus_tag="PC366_001410"
     CDS             complement(37465..37836)
                     /locus_tag="PC366_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDF2576941.1"
                     /translation="MKLKLLVEEYAVCRLNNDSKIPTWIDTEKFYSITRTDDELSVVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIEDACKILSCNGYEVE"
     gene            complement(37989..38249)
                     /locus_tag="PC366_001411"
     CDS             complement(37989..38249)
                     /locus_tag="PC366_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HDF2576942.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGVAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            complement(38438..39382)
                     /locus_tag="PC366_001412"
     CDS             complement(38438..39382)
                     /locus_tag="PC366_001412"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HDF2576943.1"
                     /translation="MIENNSEKIKVLENDIKQLITISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSAYEKVTLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSMVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYKKFRNIGKCL"
     gene            complement(39403..40257)
                     /locus_tag="PC366_001413"
     CDS             complement(39403..40257)
                     /locus_tag="PC366_001413"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HDF2576944.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKSLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKELLY
                     QILAMHKK"
     gene            complement(40272..41633)
                     /gene="accC"
                     /locus_tag="PC366_001414"
     CDS             complement(40272..41633)
                     /gene="accC"
                     /locus_tag="PC366_001414"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HDF2576945.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEDNNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            complement(41649..42101)
                     /gene="accB"
                     /locus_tag="PC366_001415"
     CDS             complement(41649..42101)
                     /gene="accB"
                     /locus_tag="PC366_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HDF2576946.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQSTSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADSFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            complement(42371..42817)
                     /locus_tag="PC366_001416"
     CDS             complement(42371..42817)
                     /locus_tag="PC366_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576947.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILITVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKENDTNLKESEV"
     gene            43092..43370
                     /locus_tag="PC366_001417"
     CDS             43092..43370
                     /locus_tag="PC366_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576948.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     VLVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            complement(43499..44245)
                     /locus_tag="PC366_001418"
     CDS             complement(43499..44245)
                     /locus_tag="PC366_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576949.1"
                     /translation="MWEGTMNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDAN
                     LRAVVKRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEV
                     PKEALSLKDMDSINLANNYLIDDDVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHN
                     VDIAKGESIDLRKIITKKIDSYYKYWEVTDNLPKDLDFIVSVSDKSVLSCEDMIIKGN
                     KTGQAVVKVILSDKNDLNTSQEVLITVNVK"
     gene            complement(44374..45018)
                     /gene="trmB"
                     /locus_tag="PC366_001419"
     CDS             complement(44374..45018)
                     /gene="trmB"
                     /locus_tag="PC366_001419"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HDF2576950.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            complement(45156..45476)
                     /locus_tag="PC366_001420"
     CDS             complement(45156..45476)
                     /locus_tag="PC366_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HDF2576951.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
BASE COUNT        17247 a         6084 c         6966 g        15349 t
ORIGIN      
        1 aaatttaaat tgtaatgaat agtaagtaat taaaaagaat ttttattgat ttttaaaaat
       61 ttagttagaa actatatcat tatggtaaag aatgtattat aatgtttaga aatattataa
      121 taaggagcga ttaaacatga atctatcgaa gaaaatagaa gataaaagaa aagctaaaca
      181 gagagctgaa aaagttaaga aagctaaaat tgctacagct ggtgtggtat taggagctgt
      241 tactggtgca gtgagtggag tacttttggc tcctaaatct ggaaaagaaa caagagagga
      301 tataaaagat gcttcacaac aaattgctga aaagataaat atgaaaactg tagatgtaaa
      361 aggcaaagta tctgagaagc tagaggataa aaaaggaaac tttatagaat caaagaaaaa
      421 aataaaaaaa tatatagata acaaaaagag tgttgaaaat tctagtgagg aagataaaat
      481 aatagatata gttgaaccag ttagtgttac tgaggaataa tatggacaat acaataacga
      541 ttaacataag tataatatat gtattattag ctatacttgc ttgtattgct ttagtttatt
      601 taattattgt acttgttaaa ctacataaga ttttaaataa tgttggaact atgttaaatg
      661 aaaatactca aaatataaat acaactttaa ataatcttcc taatgttgta gaaacttttg
      721 gagaagtagg agaaaatatg aaagatgtaa cagaagtagt tactgaagtt acagcagatt
      781 ttcttgttac taaagacagt gtcaaatcaa atatggatgt tatagtcgat atattgacta
      841 taattaaaaa tatttttcta gataaaaagt aataaattta atataaaata agatataatt
      901 taaacgacct taaaataaca tttataaggt cgttttttat tagcttgatt tgacactatg
      961 tgtttttaat aattggtaat attcctcttt atcatttgaa catatatatc tatgcttgtt
     1021 gtttcaatta catccataag aacatcttta cattcaagct caaaatcttc cattccttct
     1081 aaatattcat catcttcatc aaaaaagata taagaattat atagccattc ttcaaatttt
     1141 tcttcaagta tatcccaata cgaactccaa aataatccac aacctgatat ataagatgct
     1201 ctactttgat ttatataaac ctcatttaga agcttttgta atctactgct ataaagaaaa
     1261 tctgctcttc cactgcttga tattaattca tttaaatctt ctattgacat taattcaact
     1321 ttaccacttt tatcataagg agtataattt tcatcaaccc atttatgtgg tttgttttct
     1381 ctgcatactg ttgctatcaa ctctacaact tttgttctta tcattttttt atcctaactt
     1441 atttattttt tataaaataa tcatgatttt ataatttatc tatttcttgt aatgctaatt
     1501 taacagtttc atatctatca gcaccattta ttactacatc accttttaca agtttattag
     1561 cttctccacc tacaacataa acctttttac ctaaaccttg cttataacta gacgcctcaa
     1621 ttattaaaga atctttcaat tgccaatgta aaatctgagc agccacttta tcagcatcac
     1681 ctgtataaac gattacattt tcatacactt tattttcccc tcccccttga gaatttgata
     1741 tagatttgtt tagtatacct tctgctatca atttagcaac tttatcttta ttattaacat
     1801 aataatctgt atctgcttta ctatctacaa aacatacttc tattaatatt gctggtgcaa
     1861 tagtatgatt aagccaataa agacctctaa catcagactt tgcaccccta tctttgaata
     1921 ctgtagctaa cctagtattc actctttctg cataggtttt gccattatta gtcttatata
     1981 ttgtttctgt ccctactgga gttgaagttg tagcatttga attaaaatga atctgaacag
     2041 ccaaatcagt ttcctgttta tttgctatag cacattggtc tgctaaatga ttacttgatt
     2101 catcaactct tcctgtataa acagtagctc cacctatttt aagccattta acaattaagt
     2161 cattcagtat tcttgtttct ttgctttcgt ttatataccc aacagctcct gtaccttttc
     2221 caattaaagt gtgccctggt attattacta ctttcaaact aacatctcct ttacaattaa
     2281 atttaacttc tatttaatat atgcataacc tagaattttg tttcttttta tatcttatac
     2341 ttttattata acccattttg taaaaatata gaatattaag taaataatgt taaaattata
     2401 attttgtata taagacatta cttgattgca ataattttat agcatattca tctattctat
     2461 atccagttct ataatatata tgtttaattc cagcttgaat tatagcctta gtacaattta
     2521 agcaaggaaa gtgagttaca taaatagagc aatctttaac tgaaatacct tcttttgcac
     2581 aataataaag ggcattttgt tcagcgtgaa tggttctaat acaatgtcca tctctcattt
     2641 catgaccaac ttcactacaa tgcttatctc cagaaatact accattatat ccagtagaca
     2701 ctattctgtt ttctgaattg acaattatag ctcctacata agctctatca caagttcctc
     2761 tttcagctac tgtttcgcac agtctcataa aatattcttg ccatgagcat ctattttcaa
     2821 gttttttatt caaatcatat acctccaaaa tttatatcta atatataaga tttatacctt
     2881 aaaaataata ttaaaaacaa atttatacga taaataaaat ttattaatac tgtttttagt
     2941 ctaaattatt tcattttaaa ttaaagttac aaggaatcta aaattatata tatctttctt
     3001 cgtaatatga atgttacaat ataaaaaact gtctcaataa aatagagaca gttttacagt
     3061 caaagtttat aatacaagtt catatttttc tttaaattct tttacagctt cgggccatgc
     3121 cttttgttct gtaatacctt tttctttagc tattttaatt gcaatctctc ttatcattgc
     3181 agcgccttct aatattccca tttttaatct cccttcaaat atctttttgt atagaatata
     3241 aatagtgcta agatttatta catgctgcat atacaatatc tatacaacac ataacttgta
     3301 aattcctttt attttcatac gtctttaacc gacatataat tatattcaat aagttttaaa
     3361 attatgaact caattataat tatttttatt tttttagaat ctaaacacta aaaattgtag
     3421 gtaaatttgt cttatgcctt tataaatatt tctacagttt taattactgg acatatctat
     3481 ttttattata aaaagcgctt aaaaatcgag aatatccgcg taaaagctgt atataagcaa
     3541 aacgattaaa ggaaaaagaa gaaatttact tgaatgttaa aatgcgttgc ttgaagcaac
     3601 gggcagtttt gcctataata tcggtaacaa ctgaaagaaa ggtggttagc cctaatgtta
     3661 agcgaaaaca ttaaaacaat caggaagtca aaaggacttt cacaacaaga acttgctatc
     3721 aaactgaatg tagtgcgaca aacaatatct aaatgggaac aaggactgtc ggttcccgat
     3781 tctgatatgt tgatttccat atcagaggtg cttgaaacgc ctgtaagcac tttacttgga
     3841 gaaactattg ttgagtcgga agttgatagc ttaaaagtga tttctgaaaa attagagatt
     3901 ataaacttgc aacttgcaca aagaaaaaac atgagaagaa aaatgtttca ttggttattt
     3961 attttattat gtgcagtcat agtaatagtt tttgtggtct tagggggact aaatagtcct
     4021 tacttggatt ggaattatac cgaccctgaa accgctgttt ttggagtagc ttttcatgct
     4081 tttgagtggc tatttgtcag attagtaccg attgtcctta taggagcaat tattggaatc
     4141 tttttgacac gtaagaaaat atgaagtaac tctgcttttt ataatatagc aagcgttcct
     4201 taaaagtgtc attctacatg gcaatcgagg acaactatgt aaggaagaac ctttttgatt
     4261 tccaactaag cgaagttatt gaggacgcca gtaggcccaa aaccgcatta agtaaagtac
     4321 aggaagcaag actgctggac ttatactctc atgcgtcaga tgcagaaaat gcgaggtctg
     4381 tagcatgatt tacaacgatt tgtacaacga ctacgagtag aaatatatgg agataagtat
     4441 tatctacgaa atcagaaaag aaatgacttg ataatttact catgttataa ttattgatgt
     4501 gaaattaata aatcgaaatt ccttttttag atttaacaat actgagtaag gaaaaagtga
     4561 atgacttttg caaggaggtg ttaatatcag gcaaataaag tcttttgttt ttccagttat
     4621 atccttaata ttcttagatc aaattagcaa agttcttata ggattattct taatggactt
     4681 tgaaattgat ataattggga aatttttaag attcaatcct gttcaaaata caaaattaag
     4741 tctctgctat ctaacaaacg gagcacaaaa atgaaaatta aatattaaat ataaagcaca
     4801 gttaattttg attaaaaagt tgactgtctt ttctttttta taaatttaag catgggtaat
     4861 aaagaaatga ctgcatttaa gcattatgta tataattgga ggcaataaaa agccagcaaa
     4921 gcccataaaa tagagctgtg ctagcaacat gatgagttat aagaagataa tcaaaagctt
     4981 acgctttatt ttaatttaaa aaaatgatta ctgtaaagaa atcatttttt attataatca
     5041 ctgatacatc aaatattcta aataaaattt ttatttatct ggaattgtat attttttcta
     5101 taatattaac tacagcgtac attgcccaag cacaaatagc caatacaaat actcccatca
     5161 ttactaaatc taatttaaat acttgagaac catatactat caagtagcct attccatatc
     5221 ttgaaactaa aaattctcca actattacac ctacccatgc cataccaata ttaattttag
     5281 ttaaatttat taaatttcct gtgtttgcag gtaatatgag tttaaataat atttgagatt
     5341 tagtagctcc aaagcttttt aacatcttaa ttttttcttc atctatattc ataaaataat
     5401 tataagctga aagtatagta acaacaacag aaatcgttac agctgttacg acgattcctt
     5461 ctattccagc acctacccaa actataatta taggagctaa agcagtctta ggaagagcat
     5521 ttaaaactac caaaaatggg tctaatattt ttgataattt ttctgaccac caaagagcaa
     5581 ttgctaccaa aatacctaat acagtaccta taacaagacc aagaacagtt tcatatacag
     5641 atattccaat atgtttaaat aattgaccac taaatgcata ttgaataaat aaattgtaaa
     5701 tatcacttgg tttgctaaat agaaatgtat ttataacatt taagtcagct aaaagttccc
     5761 agattacaat aaaaccaatt aaaattaata gctggtagaa taatacattt cttttttctc
     5821 tttttacacc tttaacatag tttatatatc cttcagatct tttattaagc ctcatgtgta
     5881 tctagctcct tccataatat gtcgaaatac ttttgaaaat caggaacttt acgtgttttg
     5941 agaggcgttt ttgttccatc catgttaagt tcaatatcgt aaatattttt tatggtagct
     6001 ggtcttttag atagtattgc aaccttatct gatatgctta ttgcttctgc tatagctaaa
     6061 aaagtgcaac taattgctta aagaaacaga attatccact tcagcaccca tataaacaat
     6121 attaagattt cctaaactgc tatcccaaat gatactatta ataatagtag ataataacaa
     6181 tctcttatca tctaaactgg cattatcaac ttcatcatta aatctcttca aattactaac
     6241 aataatatca atattaatac tgtcactact aatattgata ttactagatt ccaaaatatt
     6301 aatcttatcc tttaaaatac taatctcatt atttaggctc tcaatctggg aaactatata
     6361 atcagaagca gtactaccag tattttttgc aagctctata actaaatttt taataagtct
     6421 ttccttatct aaaatttgat ttttaagtaa attagtctca gatttaaaaa tattaaaaac
     6481 attatcagtc ttaatgttat tactattgaa tgcacttata atagactctt ctttacaatt
     6541 cttaatttta tctataacta aactttcaac taatggacca ttaagatttt tacagttgca
     6601 actatcagac ccaagtgttt ttttagtacc acaaatataa taatacttta aatccttgtc
     6661 agtttttttg cctttatagg taattctcat attagaacca catttaccac attttataag
     6721 accagataaa agagcagttt ttccagttga tatccttgga gttttatcac gatttttatc
     6781 taattgattt tgtacttcaa gccatatttc aggttctatg actccatggt gttttgcaat
     6841 tgctgctatt gagttagatg tatttttagc ataggtaagg attccacatt ttctatctgg
     6901 agtacctaca acatccatac cactattttt aaggtaatct aaaatttcat cattagcttt
     6961 tacatatgct ggatttctaa gtattctaga taaagaacta gggtcaaatt taccaccacg
     7021 aggacccctt attccattat tatagacata tttatataac ttagataagg acctaagttc
     7081 taaatattta ttgtatatta gctttacaat ctccatttgt tcatcattta cttgaagctt
     7141 atacatactt ctttctttta gattttcatc taagaatgtg attttttcac tgttgaatcc
     7201 atgaggtgta ttgcctccaa gccatctacc actacgggct aattcataca tgttgtcttt
     7261 tatacgttct gctattgttt ctctttctaa ttgagcaaat acacttgata taaacatcat
     7321 agctcttccc attggagttg aagtatcaaa ttgttctttg atagatataa atgatatgtt
     7381 tagttcattt aatttttcta ttaaagtaga gaagtcagat acatttctcg atatcctatc
     7441 taatctataa caaactaggt aactaaattt cttatcttta gcatcctgca tcattttctt
     7501 aaattgtggt ctatctatat tgctaccact aaatccctca tcttcatata tcaaaaaatc
     7561 ttttacacca atagactttg cataatcaat acataattgt atttgatttt ctatagaatc
     7621 accttttcca gtaaatcttg attttcttga ataaattgca gctttcaaaa ttaaaacctc
     7681 ctataaatta ggatatatat ttgaaattat ttatatacaa ccttttaagt aaacttatta
     7741 gaataaattt attaattagg taaatttata taattctact ttttataata tatgactatt
     7801 tattttattt ctttactatt caagttctaa atcaataata aattttgata tttaattgta
     7861 tcaggacaaa tctctaattt catatattat taatataaaa tcataggtta gtgtgaaaaa
     7921 gttgaaattt aaatatttta aaagataatt ttttggaact aataggtata acaaaaattt
     7981 atagggggat tgcatatgga aatcaatgtt atagaaattt tccctaaaga taaagctaaa
     8041 cttaataaaa tagaaatgga taaagctagt tggtttgtaa atataataag taaaaaatat
     8101 cctaaagaag ctttaaatga agcatttagt attttagaaa aagaattaaa tataagtaaa
     8161 gctaatacat aagctttgat tattgatttt atatactatt ggttttatac gctatgactt
     8221 gacattatat taatcaaata gtatattttt aaatatagca caatgaagtg ttaaaagagc
     8281 aatggagctc catagataaa gtctatggag cttttttgcg tatttaactt aaggaggata
     8341 gagctttgaa taactttgag attaaaacta gaataaaatt tggagaaggt tcactaaaag
     8401 ttttgcaaga attaaaaaac aaaaatgtat taataataac agaccctttt atggtgaaat
     8461 caaaaacaat agataaaata acatctaatt taataaactc aacatatcaa gtttttgaag
     8521 aaatagtacc agacccacca atagaagtag tagtagcagg aatagaagca tttaaatcta
     8581 taaatccaga cgtaataata gcattaggtg gtggttctgc aatagatgca gcaaaatcta
     8641 taatggactt ttctaaaaaa atattaaaaa ttaacgaagt agagtttata gcaataccaa
     8701 caacaagtgg aacaggttca gaagtaacat catttgctgt aataacagat agtcaaaaaa
     8761 aatgtaagta tccattagtg agtgatgatt tacttccaga tatggcaata ctagacccag
     8821 agcttgtaaa aactgtacca aattttataa cagcagatac agggatggat gtattgacac
     8881 atgctataga agcttacgta tctacaaatt ctaatgactt ttcagatgca ctagctgaaa
     8941 aatctataaa gttagtattt aaatacttaa taaaagcata taaagatgga aatgacatag
     9001 aagctcgaga aaaaatgcac aatgcatctt gtttagcagg tatggcattt aaccaagcat
     9061 cacttggcat aaatcattct attgcacatg tattaggtgg aaaattccat ataccacatg
     9121 gaagaacaaa ttctatatta cttcctcatg taatagaata taattcatca atagtaggat
     9181 atactaacac aacttactct gatacagcta aaaaatatgc acaaatagca gaattagtag
     9241 gacttgggag tgctaatata agaatatctg ttagaaattt agtaaatgaa ataaagaaac
     9301 tacaaaaaga aatgaatatg ccaactaaat tgacacaatg caaattaagt ttagaagata
     9361 taactaatga agaaagagaa atagcaaaac ttgctataaa agatacttgt acattaacta
     9421 atcctaaggt accaactgaa gatgatataa taaacatatt aaataacatt aaataactac
     9481 attttattac atgtaaatat aatattatac aaatagggaa aatgttttta aaaatataaa
     9541 ttatatattg acaaatataa aacataaaac tataatgaaa gtatcacaaa ggcgtgatac
     9601 tttagtagaa agcaatggag cttcttagga atattaatat tattcttatg gagctccttt
     9661 tattttaagc aaatagcttt ttaataaact atattcaaag aaagcaggga ataaatttga
     9721 ctgaagaatc taagcaaaga gttattcaag aatatgttcc tggaaaacag gttacattag
     9781 cacatatcat agctaaccct aatgaagaca tatataagaa gttaggatta gtacttgata
     9841 aaagagatgc aataggaata cttacaataa caccaagtga agcgtcaata atagcagcag
     9901 atgttgctac aaaggcttca aatgtatctt taggttttat agatagattt agtggttcag
     9961 tagtaatatc aggtgatgta agttctgtag aatcagcgtt aaatgatgtt ttagaagtct
    10021 taggaaatat gttaaacttc tcatctacaa aaatcacaag gacataataa tacaatgaag
    10081 aatataatat ttatgggaaa gacaggtagt ggtaaaacta ccttatgtca aaaactagac
    10141 cagttagaat taaagtataa aaaaactcaa tcagtggaac tttataataa tgcaatagat
    10201 actcctggtg agtatatgga aaatagaaac ctatataatg ccttaataac aacatcagca
    10261 gatgctaaaa ttatagcaat agtgtatgat gccacacaag aagaaaatta tatagcacca
    10321 ggttttgcca gtatgttttg caaagacgta ataggaatta taactaaaat aaataaagct
    10381 actgaaaacg aagtcaatat agcttatgaa agactatcac tagcaggagc aagtcaaatc
    10441 tttaaaatag acacagttga tgatattgga cttgaaaaat tatttaaata tctagaaaaa
    10501 tctaaaaata tagatgaagt ttaaggggaa atattttttt attcaaaaat attattaaag
    10561 tatgataaaa taaaaaaatg tataaactat tttaagaaga tttaatcttt aagcgaggta
    10621 ggaacatggg gaaaaaaata ctattggttg atgatgaacc actgttaagg atggatacaa
    10681 aagatatatt agaaagtcat ggctatgaaa taataggcga agcaagtgat ggatttgaag
    10741 ctgttgaaat gtgtaaaaaa cacaaacctg atttagttat aatggatata gagatgccaa
    10801 tacttgatgg tataaaggca ggcaaaataa tatgtaaaga aaatctagct ggtggagtac
    10861 ttttattaac ttcatttgaa gataaagaat acgtagaaaa ggctaaaagt ataggtgctt
    10921 atggatattt agtaaaaaca gcaagtgaaa aatcacttat cccaaccata gaaatgtgtt
    10981 taaataaggt aaatgaattt gaaaaaatga aaaaagattt agaaaaagta aattctaaat
    11041 tgaatgaaag aaaattagta gaaagagcaa aaggtatact tataagagag tttaagattt
    11101 ctgaggatga agcatacact agaataagaa aattaagtat ggataaaaga actacaatga
    11161 tggaaattgc caaaatgatt ataataggat acgatgacta atacgataaa aaaaatatca
    11221 actgcacaaa catacttaaa taataacgaa attgaaaaaa ttatagaagt atcaaaatcc
    11281 ttagatttaa tggcttcttt ttatgaggct gatgttttta tagatgtact aagtaaattt
    11341 gatgatgaag caattgttgt ggcacatggt agacctaaag aaaagtcaat gtactgtgaa
    11401 aatgttatag gtaaaaaggc tttaattgaa aatgaaccag gagttataaa gtgcttaaaa
    11461 acaggagaaa gagtaagaga tattaaagct ttaacacagg aatataaact ggtcaaacaa
    11521 aatattcagc caataacact agatgacaaa gttttagcag tactaatagt tgaaaaagat
    11581 ataagtagtg aagttaagaa tgagtttaat gctagtgaag acgaagaaaa taaaaattta
    11641 catcagttta taaaacttat cggaaataat gactttttag ttgataattt aaattcagcc
    11701 atattaatat ttgataaaaa tggaaaatta aaaattaaaa atcgtattgc aactgagata
    11761 tacaaaaatc ttgggtttgg atatgatata caagatatgc attacaatga tttagatata
    11821 gaaaccaaca cctttgaaaa tatattaatg gatgaaaatt atgatgagac aaatgaagtt
    11881 tcaataggta atatgttttt taaaataaag accatataca tcaaagatga tgaatttaag
    11941 gtttgcaaaa tagtacaaga tataagtgat ttaaagagaa aagaagaaga attagtttta
    12001 aaaacagtgg ctataagaga agctcatcat agagtaaaaa ataatcttca tacagtaata
    12061 tctataataa aaaaacaaag tagattatct caaaatgatg aagtaaagca gtgtttagat
    12121 aacataataa acagagtatt tgcaatactt tcaactcatt atttactatc taaagaagtt
    12181 gataataata tatctatacg agaaggtatc aatttattag tgtcaaatat tcaaggtggc
    12241 tatttattta gtaaggatat agatatacgt ataactggtg aagattttaa aattagtgga
    12301 gaaaaagcaa cagcaatact tttggttata aatgaaatac tacaaaattg ttatgaccat
    12361 gcattttcgg atagagaaca tggtactata caaatattaa taaataaaga taacgactat
    12421 agaaatattg ctattataga tgatggaatt ggatttgata gtaataatat aaataaaaat
    12481 agcttaggga catatataat agatagttat ataacacaga tgttaaaagg aaatatagag
    12541 agaaaaagta atgagaatgg tacagaagta ttaattacta tacctacaca aattaatatt
    12601 taaataataa ctcatctaca aagtagtagt tttaattgag caaagaggct taaggttatt
    12661 aatagattaa gttaattgaa tgtatttata aaaattataa gtatatattc aatttaacag
    12721 gtatttatta taactttaag cctctttgct tgtttaagac atacttaaat tttaggaggt
    12781 gagaaaatga gagaagagtt attaagtgtt ggtattgaca ttggaacaag tactactcag
    12841 ttaatttttt ctaaattaat agtagaaaat actgaatcaa atttttcggt acctagaata
    12901 agtatagtag acaaagaaat tatttataaa agcaaagttt atttcacccc tcttatttca
    12961 aataatgaaa taaatggtca acaaataaaa gatatagttg aaaatgaata taaaaaagca
    13021 aatatatcta aagaggatat acatacagga gcagtaataa taactggtga aacagctaga
    13081 aaagaaaatg caaatgatgt acttcatact ttgagtggat ttgctgggga cttcgttgtt
    13141 gcaacagcag gacctgattt agaaagtata atatcaggaa aaggagctgg agctcatatt
    13201 tattcaaaag aacattcaac tacaattgta aatatagaca taggtggggg aactagtaac
    13261 atagcctcat ttaaaagggg agaagtaacc gatactgggt gtttggatat aggtggaaga
    13321 cttgtgaaga tagataaaat aagtaaaaaa ataacttata tatcacctaa aatagataaa
    13381 atcataaaag ataataattt aaatcttcaa gtaggcacaa tggctactgt agaaaataca
    13441 aagccaatag tggatataat ggttgactta ttaatggaaa gcataggatt aaagaaacag
    13501 acacctttgt ttgattttat aataaccaat aaatcaataa gtatagatga aaatattaaa
    13561 aatgtttcat tctctggtgg agtagctgat tatatttact atgatggaga aataaaagat
    13621 tattttgaat atggtgactt gggaatttta cttgggcaaa caataaaaaa ttgtgaatac
    13681 cttaaaaaag taaatgtagt taaatctatg gaaacaataa gagccacagt ggttggggca
    13741 ggttctcata ctactgaagt aagtggaagt acaataactt acactagcga aaagtttcca
    13801 cttaagaact tgccagtttt aaaattatca gttgatgaag aaacaggtac ttcaaaacaa
    13861 atcagtgaag ctataaaaaa taaacttaat tggtttaaac tagaaaatga tttgcagaaa
    13921 gttgctatag ccatgatagg aaagaaaaat ccaacctttt tagatataca agagtatgct
    13981 aaagggtttg tagatggaat gcaacaaatc atagaaaatg atttaccttt tatagtaatt
    14041 gttgaaaatg atatggcaaa agtgttaggt caagcaatat atgcattatt aaattatgaa
    14101 aaagaaattg tttgtataga cagtgtcaag gttgaaaatg gagactatat cgacattgga
    14161 aaacctatag ttgaaggtaa agttttacct gtggtaataa aaacattagt ttttaattaa
    14221 tagaaggagg taagtaaatg attttaaata caaaattatt tggacgtact tatcagttta
    14281 aaggcttata tgatgtaatg gctaaagcta atgaagaaaa atcaggagat aaattagcag
    14341 gtcttgcagc agaatcagct gaagaaagaa tagcagcaaa agttgtttta tcacacataa
    14401 aattggagga tataagaaat aatcctgcag tggcatatga agaagatgaa gtaacaagaa
    14461 taatacaaga tgctgtaaat gaaaaagttt atgaagaaat aaaaaattgg acagtatctg
    14521 aacttagaga atggctattg gattcaaata ctacaagtct tgatataaga agaatatcaa
    14581 gaggattaac ttctgaaatg atagcagcag ttgcaaaatt aatgtcaaat atggacttag
    14641 tttatgcagc taaaaagata aaggttactg ctcactgtaa tacaactata ggagaacaag
    14701 gaacattatc agcaagactt caacctaatc atccaacaga cgacccagat ggaatacttg
    14761 catcacttct tgaaggttta acttttggta taggagatgc agtacttgga ttaaatccag
    14821 ttgatgactc tgttgagagc gttactaaag tattaaaaag atttgaagaa gtaaaacaaa
    14881 aatatcagat accaactcaa acatgtgtat tggcacacgt tactacacaa atggaagcaa
    14941 taagaaatgg tgctcctgca gatttaatat tccaatctat agcaggttct gaaaaaggaa
    15001 atgaagcatt tggatttaat ggcgacacta tagaagaagc tagacagtta gctttaaaac
    15061 acggtacagc tacaggacct aacgttatgt attttgaaac tggacaaggt tcagaattat
    15121 cttcagaagc acatcatgga atagaccaag ttactatgga agctagatgc tatggatttg
    15181 ctaaaaagta tgaaccattc ttagtaaata cagttgttgg gtttatagga cctgagtact
    15241 tatatgatgc tagagaagtt gtaagagcag gacttgaaga ccactttatg ggtaaactac
    15301 atggcttacc aatgggtgtt gatgtttgtt acactaacca tatgaaggct gaccaaaatg
    15361 atatggaaaa cttagccata ctattaacaa cagcaggatg tacgtatttt atgggaatac
    15421 ctcatggaga tgatgttatg cttaactatc aaacaacagg ataccatgaa acagcatcac
    15481 ttagagaaat gtttggacta acagcaataa aagaatttga tgcttggatg gaaaagatgg
    15541 gattctataa agatggtaag ttaacagagt tggcgggaga cgcatctgta ttattaggat
    15601 aggaggtatt taatatgaat gagaaggatt taaaagcatt ggtagaacaa ttagttggac
    15661 aaatggttgg agaattagat actaatgttg tatctgagac tgttaaaaag acaactgaag
    15721 ttgtagtaga caacaatgct tttatagatg atataacaga agttgatata agaaagcaat
    15781 tactagtaaa aaatcctaag gatgcagaag cttatttaga tatgaaagca aaaacacctg
    15841 caagattagg tataggaaga gctggtacta gatataaaac agaaacagtt ttaagattta
    15901 gagcagacca tgctgctgca caagatgctg tattctctta tgtagatgaa gaatttataa
    15961 aagaaaataa tatgtttgca gtggaaactt tatgtaaaga taaagatgaa tacttaacaa
    16021 gaccagattt gggaagaaaa ttttctcaag aaactataaa taatataaaa tctaaatttg
    16081 gtacaaatca aaaggtttta atattagttg gagatgggct tagctcagct gcaatagagg
    16141 caaatttaaa agactgtgtg ccagctataa aacagggtct aaaaatgtat ggtatagatt
    16201 caagtgaaat tttatttgtt aaacattgta gagttggtgc tatggaccac ttaggtgaag
    16261 aattaggttg tgaagttata tgtatgttgg ttggagaaag accaggatta gttactgctg
    16321 aatcaatgtc agcatatata gcttataagc catatatagg aatggcagaa gcaaaaagaa
    16381 cagttatatc aaatattcac aaaggtggaa caactgcagt tgaagcaggt gctcatatag
    16441 ctgaacttat aaaaactatg ttagataaaa aagcttcagg aatagacctt aaataaagtc
    16501 gagggagtgt agaatatgaa aaatgatgta attcgtccta atatactagg aattaaaata
    16561 atttcgaata taagtccaga aatggcacaa aaactagaat taaaatcaca tcacaaaagt
    16621 ttaggtttaa taactgcaga ctgtgatgat gttacgtata cagctcttga cgaagcaact
    16681 aaagcttcag aggttgatgt tgtatatgca aaatcaatgt atgcaggtgc tgcaaatgct
    16741 tcaacaaaac ttgctggtga agtattagga ataatagcag gcccaagccc agcagaagta
    16801 agaagtggtc taaatgcagt agttgatttt ctagagtatg gagcaacttt tataagtgca
    16861 aatgatgatg attcaatagc atactatgct cactgcgtat caagaacagg tacatacctt
    16921 tcagagatag caggaataag agaaggtgaa gcattagctt atttagtagc accaccactt
    16981 gaagcaatgt atgcactaga tgcagcaatg aaagctgcag atgttaagat gtgtgaatta
    17041 tttgcacctc caactgaaac aaactttggt ggagcattac ttacaggttc tcaatcggct
    17101 tgtaaagcag catgtgatgc atttgcagaa gcagtaaaat cagttgcaga caatccaaca
    17161 ggattttaag gatagttaga tggatgctat aggcttaata gaagtaatag gatatgttgc
    17221 tgcaatagaa gcttctgatg cttgtttaaa atctgcaaat gttaatattg taagaattga
    17281 taaggttggg gcaggtattg ttactttaac aatatgtgga gatgtcggtg ctgtaaaagc
    17341 tgctttagaa gcaggtgaaa tagcagcttc cagagttggt acattaagaa catcacatat
    17401 tataccgaga atccataatg aagtaacaaa tgctttattc aaaactaaag aacctaaagt
    17461 ctgtgaagtt tcagaagata aagaaaaaaa ctttgagatt acattggaaa taactgataa
    17521 tgtatcgaaa aatttatcag aaaaagaaaa tgtaatttta gatgtcaatg aaaacagtgg
    17581 agatactgaa aatttatata gtgatataga taaaacaaac aaaaaaattg aaacagttga
    17641 tgatagttta acagaagcta atgaggaaaa aatagaaaat actaatgata aagaagtatt
    17701 ggaacaagtt aaaatagaaa attccgattt tgatagagat gacctatcaa agaacagtgt
    17761 aaaaaaactt aaagctatgg ctaagaaatt agattcttca ataacttata aagatttaaa
    17821 tgttcttaaa aaagaagaat taataaactt agttaaaaag cttagcagaa gggatagata
    17881 gttatgacac ttttagataa agatttagta tctatacaag aagtcagaac tcttgtaaga
    17941 agatctaaag tggctcaaga gaaactttct aaaatgagtc aagagcaaat agataaaata
    18001 gtaaaagctg ttgtagatgc agcatttaat aatgctacta aattagctaa aatggcaaat
    18061 gaagaaactg gatttggaaa atgggaagat aaagtaatta aaaatacttt tgcatctatg
    18121 ggagtttatg aaactttaaa gaacacaaaa actattggaa taattggtga agataaagaa
    18181 gccaatacga tagatatagc tacaccagtt ggagttgtgg caggtcttat accttcaaca
    18241 aacccaacat caacagtaat atacaaaact ataatatctc taaaagcagg aaatactata
    18301 gttttctctc cacatccaaa tgcaaaaaac tgcatacttg aaacagttaa tataataagt
    18361 gaggctgcta taaaggctgg agctccagag gattcaatat tatgtataac taatccaagt
    18421 atagttggaa ccaatgaatt gatgaaacat aaagatacaa acttaatact agcaactgga
    18481 ggagaagcaa tggttagagc tgcttactct tcaggaacac cagctattgg agttggacca
    18541 ggaaatggac cagcatttat agataaatca gcaaatgtta aattagcaat caaaagaata
    18601 atagattcta aaacttttga taatggtgtt atatgtgcat cagagcaatc tatagtaata
    18661 gaaaaatcta tggaagaaac tgttttaaaa gagcttaaaa atcaaggtgc atatgtttta
    18721 aatgaagagg aaagtgaaag attagcaaaa ttcatattaa gagctaatgg tactatgaat
    18781 ccacaaatag ttggtaaaag tgttgaggta atagcaaatt tagcagactt aacaaatata
    18841 cctaaaaata caaaagttct agttgcaaga gaaaataaag ttggtcacaa tgtagcctat
    18901 tcaagagaaa aacttacacc aatactagcg ttttatgttg aagaaaatgt agaagctatt
    18961 atgaacagat gtagagaaat attgttaaat gaaggtgcag gtcatacatt ctcaatgcat
    19021 gtaaatgatg aagaattggt aaaaagattt gcccttaata tgccagtatc aagaatactt
    19081 gtgaatactc cttcagcact tggaggaata ggtgcatcaa caaaccttgt accagcacta
    19141 acacttggtt gtggtgcaat aggtggaagt tcaacttcaa acaatatagg accacttgat
    19201 ttaataaatg ttaaaagagt agcttatgga atcaaagaaa tagaagaact tggaagagat
    19261 aaatctcaag ttgaaaaatc aatgtttgac tcaatggata aagaagaatt aataaatctt
    19321 cttgttcaaa aactagtcaa agaactagca taactaaaat aaacaatgaa acttatggct
    19381 atcgctataa atttataaaa atataaacta taaaaaacta taaaattaaa tttttggagg
    19441 ataagattat ggcaagtgca aacgcattag gaatgataga aactaaagga ttagtaggag
    19501 caatagaagc agcagatgca atggttaaag ctgcaaatgt acaattagta ggaaaagagc
    19561 aagtaggtgg aggattagtt actgtaatgg taagaggaga tgttggagct gttaaagctg
    19621 ctacagatgc aggagctgca gctgccgaga gagttggaga actaatatca gttcatgtta
    19681 taccaagacc acactttgaa gtagatgcta tattaccaaa ggtatcagct gagtaatata
    19741 agaataattt taaaatttaa attttgattg aaaaagaggc tatctcaaaa atgagtctta
    19801 ctaataaact caatgtattt tgaggtagtc ttttttatac atctaatagg agatgtgata
    19861 aaatgggtgt tttaacagaa aacgaagtaa aaagaaaaat tggaaaaaac aaaaataata
    19921 taactgaatt ttatatagaa aaaggtcaaa taataactcc ttctgcaaaa tcttatttag
    19981 ctgagagaag tattgagctt aaatatgttg ataaactttc agatgtaaac aatgaaccta
    20041 aagaagttgt aaaagaagta gttaaagaga aaaaatataa atatactact gtatttggcg
    20101 ctaaattgga tgaaaaacca gaacatatga ctcaattaaa tggaaatctt ttagttttta
    20161 aagaccataa aagaataata ttgagaggaa aaatagattc tcttgaatca gaaatactaa
    20221 aggtacagat actttgtcag aaactagata tgccaaagct tgttaaggaa ttgcaagaag
    20281 tattagactt tgtaagaaat ataatgagat gtgaagtttt agatgaaaag ctagaagact
    20341 ttaaactttt aggattaact cctcaagaac ttagagaaca atctcactat cctaaaaaat
    20401 actttggtat aggacatgaa ttcccaagtt atgaaatggg agaagtagta gtagctataa
    20461 atagtataag aagtaataca cgagaggttg aacttgcagc ctatgaagca tttaagggtg
    20521 agtatggaaa tgttcacaga gaagatttaa taaaggcact taatagatta tcgtcagtat
    20581 tttggataat gatatataag gttagaacta ataagtataa gtagttggag gacataatgg
    20641 agaatctatt aaatgaaata gtggaagaag taataactag agttaaaaaa gaagcattta
    20701 tagaagttga agcatcagga agacacgttc acttaagtag agaagatgtc gataaattat
    20761 ttggagaagg atatactctt acaaaactaa aagacctatc tcaaccaggt caatatgcat
    20821 gtaaggaaag agttacaata actggtccta aaggaagtat aaaaaatgta gttgtacttg
    20881 gaccatgtag aaatgaaact caggtagaaa tatctttaac agatggttca actcttggac
    20941 taaaagctcc tataaaacaa agtggagact tagaaggtac tttaagtatt aaaatatcaa
    21001 cacaatatgg tgaagttgaa cttgataagg ggttaatggt tgctaaaaga catatacaca
    21061 tgactcctaa agatgctgaa aaattcaatg tatgtgataa agagatagtt gaagccaagg
    21121 tgatgggtca aagaccttta acatttgatg atgtagtaat aagagtgagt gacagtttta
    21181 aaacttatat gcatatagac tatgatgaag ccaatgcatg tggttattca aaaggaactg
    21241 ttgctaaaat aataaagaaa gcataaattt aacctactat ataaattacc tctagggagg
    21301 atttaatatg aattatgata accttgtaga tttaataacg gaagaaatct ataaaaaaat
    21361 aaatagtaat gaaataaaaa tatctaataa acctaaagct gtgattgtat ttgaacaaga
    21421 taacaataaa tttaacttat taaaagatga atttgaaata ctagaatttg ataaaagtat
    21481 aagggaatgt gaaatagtga tagtttcaag actttgtatg agggggctat cgaatatagc
    21541 acttggaaat tcaacaagtg atgaagaaag atttatacta aaaatgatta tgaaaggcaa
    21601 aaaagtatat gtcctagatg aaggaattga atacaaaaaa tataaggata ctgcaccaaa
    21661 agcattatat aagaaattta tgtcatttga agatgaaata tgtaaatttg gtgtagaaat
    21721 tataaaagac ttaaatgtta taactaaaaa taagttaaat ataaagaaag aactagaaag
    21781 tactagaggt tctaaaaaag aagatacaaa agttttagat aaagatgttt taaatttaac
    21841 cagtgtagaa agtgtaaaaa tagataatga atttagtttg gatttaagga ataaaaaact
    21901 tatatcggaa gctgacttaa gaaaaccaac tataaatgga gttaaaaaca tattagttaa
    21961 taaaaaaagt ataataacac cattagctgt agattttatg agaatacacc atctcaaact
    22021 aaagaaactg taaggaggta attttatgga tataggaaaa gttgtaggta atgtttgggc
    22081 tacaagaaaa gatgaaaaat tatgtggcca aaaactttta gttgtaaaaa ttttaaaaac
    22141 taaagacaca tacaaggaag gcttcatggt tgcagccgat aatgcaggag caggaaatgg
    22201 agacttagtt cttatatcca aaggttcctc agctagagag tcgattgaaa aatctcatgt
    22261 tccagtagat gcaactatag ttggagtagt cgattcgttt gaggtgtttg atgaataaaa
    22321 gtataggagc tatagagttt aaaagcattg ctaaaggtat agaagtatcc aatgaaatga
    22381 taaagaaatc ttcagttgat gtattgtact taaaaagtat ttgcccaggt aaatttctaa
    22441 taatagtagg tggagaaact tcttatataa atgaatgtgt agattatgga ataaaacttg
    22501 gagaaggata tattgtagat aacttcgtaa taaatgcaat ttcacaagaa atattagatg
    22561 gatttaaaaa taagtatcaa aagctagata gtatagtctc tataggcgtt gttgaaagta
    22621 gtaaagtatg cgctggaata aaaatgcttg ataagacttt aaaatctggc gacttagtat
    22681 tagtaaaact tcaattatct tttgctatag gtggcaaatt agtatatgta gtagcaggag
    22741 atttaagtag tttagaatat gcattaaaag aaagtgaaaa tgtagtaaga gaaaaagaag
    22801 taatatataa gactgtaata ccatcagtag acagtcaaat aataaaaagt ctaataaaat
    22861 aatgggggga attatgagta taaacgaaat tataatctat gtaatggtag tcttcatggt
    22921 acttggagct atagataaat gtataggtaa caaatttggt cttggagaac aatttgaaga
    22981 aggtataatg gcaatggggt cacttgcagt tgcaatggtt ggtgttatat gtttagcacc
    23041 agttcttgct gatgtattaa gaccaattgt agtaccagta tttaatatac ttggagctga
    23101 cccagctatg tttgctggaa gtttattagc taatgatatg ggtggtgcgc cacttgcact
    23161 tgaacttgcg aaagacccta attctgggtt atttggtgga ttaatagtag gggctatgat
    23221 gggacctaca atagtattta taataccagt tgcgcttgga ataattgaaa aagaagacca
    23281 aaaattctta gcaacaggaa tacttgcagg tataataaca atacctattg gagcattcgt
    23341 tggtggatta gttgcaggat tcgaggtaat gatggttctt agaaacttag tgccaataat
    23401 aatatttgca gtagttatag cacttggatt attaaaattc gaaaatgcta tgataaaagg
    23461 attcacatac tttggaaaag gtgtagtaat agttataact ttaggacttg ctgctgccat
    23521 agttgaagct ttaacaggaa tagttgtaat acctggaatg aaaccaatca gtgaaggtat
    23581 agaaatagtt ggagatatag caatagtttt agcaggagca ttcccattag tgtttgttat
    23641 aacaaaggta tttaataaac cattaatggc tttaggaaaa gttcttggaa tgaatgatgt
    23701 atcagcagca ggccttgttg caagtttagc taactgtata ccaatgtttg gtatgatgaa
    23761 agatatggac aatagaggaa aaataataaa tgtagcattc tctgtatcag cagcattcgt
    23821 atttggagac cacttaggat ttacggcagg atttaattct aatatgataa caccaatgat
    23881 agttgctaaa ttagttggtg gtataacagc agtattgtta gctatggtta tcgcaaataa
    23941 gacactaagg aaggagaatg tataagatgg atatatcaaa tatagataaa aatttaattg
    24001 aaacattagt aagacaaata atagaagaaa aaataagtgg aactaaagac acagtagatt
    24061 ttgttagaaa taaagacatt agtggaataa cttctataaa gttaccaact gtaaaagtta
    24121 gtgaatctga tagattagat acagggaatc caagtgatgt agtttacaca aaagatttat
    24181 ttacattaga ggaaagccca agattaggtt gtggtatgat ggaaatgaaa gaaacaactt
    24241 ttgattggac tctaaactat gatgaaatag attatgtaat agatggaact ttagatataa
    24301 taatagatgg aagaaaggtt tctgcttctt caggtgaatt aatattcata ccaaaaggaa
    24361 gtaagataca attttctgta cctgattatg ctagatttat atatgtaaca tatccggcag
    24421 attgggcatc tcaaaattaa taaaaatcaa gttaagttaa taataatcaa ataaataatt
    24481 taaaatacaa actcttaaat aaacacacat atttaaaaaa gctatgaatt aaaattcata
    24541 gcttttttta taaagaatgt tatattttag acgtattttt tctatattta ctgggagaca
    24601 tattatattt tttattaaat aatctaataa aatgctctac atttggataa ccaatactat
    24661 tttactgata atcttttcct tatcactaat cttacatttt aaaatattat ttttactcgt
    24721 aatattatca taagaatttg tttcttattt aaaactaatt agaattataa agtttattgc
    24781 catgttatta ataaaataaa tccagttaaa tcgagtgcta gttaaagtaa taagaaactt
    24841 ttacaatggt ttcctttatc gattgaaata aaagttaata tggtataata tctaaagaga
    24901 gaatcttatc aattagaata tgcatagaaa caagtggctt aaaaggagac gttatatgga
    24961 agagatagta aagaaggaac aagcaagtat gaatgatatt tttttgtatc ttaaagctaa
    25021 atcaaactca ttatataaat ttgtaatatt atataatgag tttatcaata aacctaaaga
    25081 ttatggaact ggggaactta taaacatggt tgaagtacat atgctaacag cgattgaaga
    25141 aaatccagga ataagtccaa ctcagttagc taaaatatgg aacagaacta aaggtgcaat
    25201 atctcaaact atatctaaat tggagaaaaa gggttatata actaaagaaa agaaagaagg
    25261 aaatgcaaaa actatattac tatatccaac cacatcagga gtagagttaa gtaaggcaca
    25321 taaactatat gacaccatag atgttacaag aacatttgaa tacttaatca aggagtgtac
    25381 attagaggag atagatagtt tttataaagt aattgatttg tttattaatt tattagaaga
    25441 atctccgcag gaaaataatg attctgaaaa agtgtagcta agattgaagt tgaataaaga
    25501 gaaatagata ttatagaagt agtacttaag tacacattat ataaaaatat aataggtata
    25561 ggattaaaaa gtttagtggt ttaaagttta accactaaac ttttttaatg tctataatct
    25621 actattattt aatttactaa aaataaaaaa actcattata ttaagatgaa aatagaaaaa
    25681 taactagaaa aatactataa tatatcagct taatacagaa aaaagttaaa aatattgaga
    25741 aaaataaaaa tgaaaacgtt ttatattgac atagagaaaa agtagtgata ccatttaaat
    25801 atagtttagt agctaaacta tatttaaatt ataataacta ttttaggggg atgttatgaa
    25861 tttaaaacaa ttaagtgaaa aatacgaaga atatgtaatt caaatgagaa gagaatttca
    25921 taagtatcca gaattatctt ttaaagaaat aagaacaacc caaagaataa gggaagaatt
    25981 acaaaaaata ggggtccctt ttgtatctat tgaaccaaat atcgtaatag ctactataca
    26041 aggcaaaaat gaaggtaaga caattgcaat tagaggagat atagatgcgc ttccaatgca
    26101 agaagattca gatgttgaat acaaatcaga atatgatgga ataatgcatt cttgtggaca
    26161 tgatgctcat ggagctatgt tactaggact tgcacatatg ctaaatgata taagaaaaga
    26221 tttaaaaggt agagtattat tagtttttca agcagctgaa gaagttggtg gcggacacaa
    26281 ggagataata cagtacttta aggaaaatgg aggaccagat agattaatag ctactcatgt
    26341 ttggtccgat attgaagctg gtaaaatttc tgttgaacca ggacctcgta tggctggtgg
    26401 gtctggttgg agaatagaca taacaggtag aggaggtcat ggttctagac cagatcaaag
    26461 catagatcct ataaagccag cttgtgatat agttttaaaa gtatcttcta taccagttaa
    26521 tcatataagt gtactagaac aatgtgttgt acatgcatgt gcaatacatg gaggaactac
    26581 aataggaaat gttattccaa acaatgcaga ggtaataggt ggatatagat attttactga
    26641 agaatcaggc aaaaaagtgt ttgacattat aaagcaaatg agtaatggtg ttggacaagc
    26701 ttatggagtg gatgtgaagg ttactcatac tggaggcata ggacctgtta tcaatgatga
    26761 agaagcagtt aagatggcta aagaaatagt ttctaatata gatggattgg agttagattc
    26821 ttatgagcca atatgtgcat cagattgtta tggtgaaata ttaaaagagt attctggttt
    26881 ttattgttat ctaggggtag gtaacaaaga aaaaggaata atatatgcac aacaccatcc
    26941 taagtacaat atagatgaag atacattaaa gttaggttgc gaatttatgg ctaaatatgc
    27001 agttgaattt ttaaataaaa ataataacta aaataaatcg aattttataa atggggggga
    27061 tgaaaatgca aggtgcatta aaggaaaata agaaaaaaag tggtggagga tttttaggat
    27121 ggattgaaag agttgggaat aaaatgccac atcctctagc attatttaca tatattacat
    27181 tgatagtagt agcattatct gcaatagcaa gctttttagg tttttcagca acaagtcctg
    27241 ctacaggaaa gttaataaaa gttatgaact taataagtgc aaaaggttta gtactattta
    27301 tgcaagagtt tgttaagaac ttccaaaact tccctgtgct tggggtagtt ttagttatgg
    27361 cagttgccac aggagtttgt gaaaagacag gatttttttc aactgccata aaaatgagtt
    27421 tatcaaaagt taaggggaat gcggttgtat ttataatagc ttttatagga gtatttgcta
    27481 atcaagctgg tgatgctgct tttgtattag taccaactct tgcaggagca atattttatg
    27541 gattaaatag aaatccatta gctggtatat tctgtggatt tgcatcagtt ggtggtggat
    27601 ttgcaacagc tgtaattcct gggggatggg acgttacgct aacgccaata actgtatcag
    27661 ctgctcaaac tattcaacct gcatttgata tgacattatt agctagttat tatgcactat
    27721 ttgtatctgc gtttatagta gctacagtat caacaatagt aacggttaaa tttatagaac
    27781 ctaaattagg taagtatact ggtaaaccag aaggtataga tgataatcaa ggttttgagg
    27841 tcacaaaaga acaagcaaaa gcagcaaagt tagcaggttt tacagtttta gcttatgtag
    27901 cgttattaat tgctttgtgt ataccagcta atagtttttt aagaagtcca gaaggttctt
    27961 taatatttgg agcaccactt atgtcttgct tacagttttt tatagtaata ctattcttct
    28021 tgccagggat tgtgtatgga atgagggttg gtaaaatcaa gactgtaaaa gacttaaatg
    28081 atatattatg tcaatcaatg gcagcaatgg caccgtttat cgtacttgca atagttatag
    28141 gtcaattctt aacgctattc tcagtgtcta atttagcaca ggtactagct ataaaaggtg
    28201 gagcattact caactcattg ccactaccac cacaagttat aatactgcta ttcttagtac
    28261 tagtagcgtt tataaatata tttgttataa gcggaagtac aaaatggatg atatttggac
    28321 cagtatttgt tccgatgtta atgcaattaa acatacatcc agcatttact cagtttgtat
    28381 atagattagg agattctgta actaatcatt tatcaccatt aaatgcattc tttataatac
    28441 ttttagcaac agtccaaaaa tacgataaaa atgcaggtat gggaactata ttctcagcta
    28501 tgatacctta cactataggt tactttgtag tacttgcagt tttagtagta gtttggatga
    28561 caataggtat accagtagga ataggtggac aagtttggtt ataaaacata tttaataatt
    28621 ttgggaggaa agaaaatgga aacaactgaa ataagataca attttgatga agtaatagat
    28681 agaagtggaa caaactgtct taaatatgat cttaagagtc aatttatgcc agaatctcca
    28741 gaagatgcac taccactatg ggtagcagac atggattttg catgtgctcc tgagataatt
    28801 aatgcaatgc atgaaagaat agacagaaaa atatttggat atagctctca acaaactgat
    28861 gattattatg aagctgtatg tggatggttt aagagaagat ttgattggaa aatagaaaaa
    28921 gagaatatat tctttagccc aggggttgtg cctgcgttag gatttttcat acaaatatta
    28981 acacaaaagg gtgatggtat cataatagaa aagcctgtat actatccttt tgaagataaa
    29041 ataactaata atgaaagaaa agtagttaat agtcctttaa agtttgaaga tggtcattat
    29101 tctatggatt atgatggatt tgaagaatta gctaaagatg aaaataataa ggtgtttata
    29161 ttatgtagtc ctcataatcc agttggtaga gtatggaaaa aagaagaact tagaaaaata
    29221 gtagacatat gtaagaaata tgatttgtgg ataatatctg atgaaataca ttgtgatatt
    29281 attcgtaaaa gtgaaaagca tataccatta gaagtagcat gtcctgatta taaagataga
    29341 ataataactt gtacagctcc aagtaagagt tttaacttag ctggtatgca attatcaaat
    29401 atagtaatca ataataagga attacaagaa aaatggatgc ttgaaacaga ttctaaatta
    29461 gctatattcc tacctaatcc attcgcaata gttgctacta aagttgctta taatgattgt
    29521 gaagattgga tgaatcaagt aaatgagtat atagatggta atattaaata tgtagaagat
    29581 tttgttaatg agtatatgcc taaagtaaag ataataaaat ctcaaggaac ttacttaatt
    29641 tggttagact ttagagggta tggattagat gcaaaacagc ttgaatatgt aatgcttaac
    29701 aaggcgaagg tattgctaga tgaaggatac atattcggag aagaaggagc aggatttgaa
    29761 agaataaatg ttgcttcgcc tagaacaatt atagaagagt gtatgaatag aataaaatgt
    29821 gcatttgaag gattataata gtaatatcta aataatatat ttgtgtattt taaaaaaaga
    29881 ctatgttaaa aaaatatttc aaagcatagt cttttaaagt tttatgatga gtttaaaaaa
    29941 tttcaaaacg ttactattat tgataatctt cacttatatg tttatattag aaataattcc
    30001 acaatatgct cattttctaa agttgcactt ttatacacct tgcttcacca atatcatgtg
    30061 taaccaaaat agtagactta ttctcattct taataatact ataaacatca tcacaaacta
    30121 ataatctagt ctgataatca agagctgaaa aaggttcatc taaaagtaga atatctggat
    30181 ttacagaaag tgttctaata agcgcaactc tttgtctcat acctccagat aattcttttg
    30241 gatacatact tctaaaatcc cataatccat aagtctttaa aaggctttca actctatcta
    30301 aagatttttt atcttttttg ccttgaattt ccaatccaat agttatatta tccattatat
    30361 ttctccattc aagcaaatta tctttttgaa acatatatcc aatatttcca gtaatcttta
    30421 tatcaccact agtcggtttt aaaagattag taagaatatt taatattgta gatttaccac
    30481 ttccagaagg accaagcaaa gttaatattt ctccttcttt caagttaaaa ttgacatcct
    30541 ttaatacttc aagctcgcct tccttagtgt agaagttcat atttatattt ttaacttcta
    30601 ctatgttgtc attcattatg ccacccccta taacttttag ctcgtatata ttatgttatt
    30661 aacaatatga cctatttgta ccatttttca taaatataat ataaatattt tgtttattta
    30721 cgtattttct tagtaacttg tacgtataaa ttataataaa taaattataa ggtaggggat
    30781 aaatttgagt aacataataa cgaatttaat agagtcagta tttactaatc caataactat
    30841 attgttttta cttgcaataa ctgtgtattc tgtttttaaa ataatagaaa ataacagagt
    30901 atattcattt gtaagttcaa aattagacga aatcaataga gattataaga caagtgagtt
    30961 ttataaaaag gtaagggatg actactatac atatagtaaa gaaaatcctt atgcagacgt
    31021 aaatataact tcatttatag aggaagttgt atctgattta aagcataata atttgccatt
    31081 gttagaaaaa attagaagta taaaaaattc atcttcaata agtatattac ttggggtttt
    31141 aggtacgttt gttggtcttt ctacaatgct tttatgtgtt gatactaaag acattataaa
    31201 ttcacttcct tcaactatta gtagtatgca aactgcattt acaactagta tatttggagt
    31261 tgtattttct ctaattatag gttactttac taagataaaa gattgtgaac atgttttgat
    31321 acaaataatg ttaaaatctg aaaatttact aacatctgaa ataactcatt ttaagtcaga
    31381 aagaatggat ttaaaagtag aagaggtaaa aaatacaata aaacaaataa gtaagtctat
    31441 agaagctatt gaaaaatttg ataaaatatc taaagattta aatgacttta atgatgaatt
    31501 tatcagtggt atagaagctt taaaaagcct tttagaaggt tctcaaagtt ctattaagac
    31561 atttgaccag agcgtaagaa aattagataa acagtttaat attttaaata taaaatttgt
    31621 aaagcttttt gataaatatg ataatcaaga taatataaat aaagagattt tatttgatat
    31681 aaaagaatct tcaaaaaata tatacaatgc cactgaaagc caattcaaaa ttagagatta
    31741 tataaaaaat ataaatgcag gatttgctct atatgaaaga agtgctcaag atttattaac
    31801 taaattaatg acccatgaaa ataaaatctc tcaaaatcaa aaaatccttt tagatgaaaa
    31861 gtttacctta gatgactcaa taaaaaatct ctcaagtatt attgaaaact tttctaatga
    31921 cctacaagtt aaactggata tgatgtttga aaattcttta gatattcaag ataagttaga
    31981 tgttatgttt aataactctt ttatgaatga tgaagttcct cttgatagtg aggaattatt
    32041 taaggatgat gttaataatg tatttaatcc ttttagtgaa gaaatttatg agatagagga
    32101 taaagaaata aaggtcatag gtgaggatga gttaaatgaa taataaatat agaagaactg
    32161 ttaacagaga atttgaaaag agtagctttt ggccaacatt tacagattta ttatctactg
    32221 tattgatggt tgtgattctt atcttattta gctcagaaag tatttcaggt tctgttgaac
    32281 aagatttagc taagaatgtc aatgcttctg ttgaagaaac ttttaaaaaa agcaaaatac
    32341 ctgtgaaggt agataaatct aatgggcaag taacttttgg tgaaaaaacc atgtttgatg
    32401 tagatagtga tgttttaaaa ccagaggcta aagaaatgct aaaaatgttt gttccaaagt
    32461 acatagagac tatttataaa gattatggtg actatatatc caaaatagtt atagaaggtc
    32521 atacagatga tgtgggaagt tatatataca acttagattt atcgcaaaga agagcatata
    32581 gcgttgctaa atttatagtg ggagatgaaa taggtgacta taaatacaaa gataaagtga
    32641 ctaagcatat tattgcaata ggaaggtcaa aagctgaact catcaaaaat ggtgacaata
    32701 gcgtgaatag agatgcatct agaagagtag aactaaaata cgaaataaat attaatcaaa
    32761 ataaataatt aaatttttat aaaaaaaaag aaggcagttg gtgtgagctt taagccttct
    32821 ttaaggaaaa agtttattta tttttgttga tacttaacat attatagttt ttagaagcag
    32881 tttgcaatat attaaacgta aatggtcgtt taaaatgcat aactggatac tactgatgta
    32941 aaatatttca ttttatataa tataaaaatt atacagtgtc aattttctat attattgtac
    33001 tataatctat tatttaaaat attatgtaaa aaaatatcat aaaaacgcat atcatgttat
    33061 aattactaga gtattatgaa tatggaggcg tagtttgtga tagaaataag tataaaaaat
    33121 aaaaaaaatt ctaaaattaa aactttgata cttttattga tagtatctat atcgatttat
    33181 ttaactggtt gtactacatc agataatgga aataatcaat caaataataa tgattctttg
    33241 tctagtagta tatcaagtga taagaatgta aaaattcatt ttattgacac tggaaatagt
    33301 gatgcaatat tgattcaaga tggtaaaact tttacattga tagatggggg agataatgat
    33361 gatgagggat taatggtaga ttacctaaac aatcaaggtg taaaagatat taaatatctt
    33421 atagctaccc attctcatgc agaccattta ggtggacttg attctgttgt caaaaacttt
    33481 aatatagaaa atgtttttgt atcgaatggt tcagcagaaa caaagagtta tagggacttt
    33541 ataaatgctt tagcaaataa gggtttatcc ccaagtgtac cgcttgaaaa taataagttc
    33601 tatttagaag attcttattt tgaagttcta aatacaaatg ggggagatac tactaatgaa
    33661 caatctctag tccttgtata tactaatggg aatgataaag ttttatttac aggtgatgct
    33721 gaagaaggta ccgaaaaaga aatactacct aagcttgaga aagtagacct tttaaaagta
    33781 gctcatcatg gttctcgtag tagttcatct caagagtttt tagataaagt aaatcctgaa
    33841 tatgcggttc ttttagtagg caagggtaat tcatatggtc atccacatca ggagacaatg
    33901 aataaattga aaaaaatggg agtaaaagta catagaagtg atgagtgttc agatataata
    33961 tttgaatcaa caggtgatgg agtatttaca agttgtaaag atggaagtta taataaaggt
    34021 gttagagaag atggaaactc tggaaaatca aacagtaata caagtaaaaa tgattctttt
    34081 aaaaataaac aaaatacatt caattcagaa gaaatagtgt attttactcc aaaaggtaag
    34141 agttatcact ctataaaaaa ttgtagtggg ctttcaagaa gtaaaaaaat attatcaggc
    34201 acaattgaag aaagtaagaa aaatgaccca tgtgatatat gttatggaaa ataacaaaaa
    34261 aacaaccaat ttatctataa agcttctgaa ctttaaatca tttaaaaaat aaaataaatg
    34321 cataaaaaaa ataagctata atcaatagat aatacatttc atctatacga atagcttatt
    34381 tttttaagta ttttttaata gctatttaat aactctaaat acaccagtta caatacctac
    34441 aatttcaact tctgagtcat tgagcataat tggttccata aaatcatttt ctggctgaag
    34501 tcttattaaa tttccttctt taaaaaacct cttaactgta gcagattcac catttataag
    34561 tgcaactact atctgagaat ttaaggccgt attttttttg tctactacaa cgtaatcttc
    34621 atctaaaatt cctgcattaa tcatactttc gccttttact cttaatacaa aattgttact
    34681 gccctttact aaactggcag ggaatggaat gtattcctct atgttttgtt gagctaaaat
    34741 gggttctcca gctgttattt gacctactaa aggaagctct attatttctt gattagctcc
    34801 agaaacatca tttactttac tacgttctaa aacttcaata gctcttggtt tagtagggtc
    34861 ctttcttatg tatcccagtt tttcaagttt atttagatga gagtgcacag ttgaagtaga
    34921 tcttaaccct acagcagtac atatttctct tacagcaggt ggataacctt ttaatgtgat
    34981 ttgagacttt ataaattcca atatcaagac ttgcttttca gttagatcta aatacataac
    35041 atcactcatt tccaaacata ttttgttttt atttccatac actttatatt tttaattata
    35101 acataatcca tttatatctg caaacatttg ttcctgattt ttaatcgtcc tcaatccatt
    35161 caaaattctt gactatatca cgttttacat ttttcttatg agctgcataa agctgagtag
    35221 ttgtgacatt atcatggtca agtaagtttt gaacatcata tatagaaaat cctgtttgga
    35281 ttagagaagt tgcagccgtt gctcttaatt tatggggact atatccattg tctctagtag
    35341 tatcaagtgg aatagatgta tattttttta ccagtgttct tatagccttt gctgtaattc
    35401 tcttattttg aagagacaaa aataaagcat ctttttcttc atcatttaat agttcatctc
    35461 ttgttctttc gttttgcaaa taatctttta ttacatgttc acaagtatga tttataggca
    35521 ttaaaacttc tttcccacgt tttctatata ttttaaattc acctcttgaa aaattaaaag
    35581 aggagatatt gagttctcta agctcattta atctaagccc gtatgtaaca aataatgcta
    35641 gtatagcttt gtcacgtaat ttagtttttc tccaatatac cttttctttc tctgtaagcc
    35701 cttcacctgt ttctactgat tcaagcatct tagcaacttc atctatctca aggcgcttaa
    35761 tagcatctgg ctgaggttta ggaagtttta ttggattgaa tccatcagtt atattattat
    35821 ctatctgaga gtttctgtat aagaatttaa atagagtaga gatggatgat ttttttcttg
    35881 ctaacgctct attgttattt tcaaaaatca atgtgttttt ttctgtattt ttgtaatatc
    35941 tactgcaata atcacctaag aataaattta tatctcttga ttttattgta ttaaaatcat
    36001 cttctgtaat atcttttaca caatctgcat ttgttaattc tttggtttca atcaaatatg
    36061 aacaaaaaaa attaatatct tctaaataag caagtcgtgt agaaactgca acagaacctt
    36121 ttaaatatat aaaataatcc ttcataaata caggaagttt attttccaaa agtagacatt
    36181 tttctatgag ttcattttct ttgataacaa tattatcagg tttatctgat ttattatgta
    36241 cttttataat tttcttatca ttattcaaaa ttaaacctcc taaaactaaa atataaatct
    36301 tttatattat tttttgatat ttataccaag tgagtataaa tatttaattt aatcattttt
    36361 tacattttta agagattagc agtgctttag atgaaattat cactaactat tccctaaatc
    36421 cacatttaaa gactagttga atttaagtac tcttttttta tttctcaata tatttataga
    36481 aatattttaa aatatattga gaaatttttt atgctctact aaaatctttt ttatataata
    36541 tttttatata tttctaacga aaccaaatat tagtaaaata tgtatttatt taactaaagt
    36601 ttttaaatgg gctgactaag cttaaaatat aggatattat gagagttact attgaaaaaa
    36661 taaaccctat tgccataaag aaacttataa atatgttata cttaactatt aaactggata
    36721 tattcaagtt atcaaatcca aataagtatg taattgaact tattacaaaa ataactataa
    36781 ctataaagct cagaccattt aagctatttt ttaaatcagc actactaagt gacatatgtg
    36841 tagatataga atacattaaa aacataaata taaaatactt caatgaatat acactaggtg
    36901 ttaacaacat tattcttata aaattggaaa tatcacctaa aataatgtgt ataaaaccat
    36961 ttatatttaa attattaatc atacttacat ataactttaa atctatattt tgagtcactt
    37021 tcatataact atctggcagt aatatcttaa aaattaaaat aatcattatt gttccaccta
    37081 taataggtgc aattcctata aagaaatttc ctatactttg ataaagatta tcttttttat
    37141 agctatgact tacatatcct agtataccat catttttact ttctattggt ctgaaaaact
    37201 taactgaatt tattttatgc atgaaaatca agcacattat caaatgactc aattcatgaa
    37261 caaacgttcc tatagctcca gttacaataa ttccagtttt tccaaaagat gaaaagataa
    37321 atttattatt tagattttct gtaatgctaa aaatcaatcc aaatacaata aatattccta
    37381 tgaaacaaaa aatatttatt acacttattt ttaaaatttc gattatataa atcataagtt
    37441 aagtcctcat gtaaaagtat ttaactactc tacttcatat ccattacagc ttaaaatttt
    37501 acaagcatct tctatatctt tttcttttac taagatatag tctgtatcat acgtagaaat
    37561 tgcaaatatg cttattttgt tgtctgctaa caaactactt aacttagata aaattcctac
    37621 aagtgaaaag tctaaaggac ctagtatctt aagtattctc cactcctttt ctgacttaac
    37681 atcagaagga atattattat ttaaacatac aacacttaat tcatcatcag ttctagttat
    37741 agagtaaaac ttctctgtat ctatccatgt tggtatttta ctgtcattat ttaatctaca
    37801 tactgcatac tcttctacca ataattttaa tttcataatg tatatttcct ccaatcttat
    37861 ttgtttactt aagattatac attaaaagtt acataaaata aaacatataa agtaaaaaag
    37921 gttcactata gtgtcctatt tctatagcca acctttaaaa cttaattaaa ttctaataaa
    37981 gagatatatt atctaggttc aattataagt ttaatggctg ttttcttatc accttcgatt
    38041 tctatatcag taaatgcggg aatgcaaact aaatccattc cactaggtgc aacaaaacct
    38101 cttgctattg caattgattt tatcgcttga tttagagctc cagctcctat agcttgtatt
    38161 tctgcaacgc ctcgttctct tagtactcca gccaaggctc cagctacaga attaggatta
    38221 gattttgatg aaacttttag tacctccatt tcaacatctc cttgttaatt tgttaaagta
    38281 tccattacct aaagtactaa atcataattg ccatttacta attacaatca tcatttaaag
    38341 tatactttta taaaaatata cttctataat cgttttaaga aaacctttat tttttttaac
    38401 cattttatta tgaaaaaact acaaatttct ttatattcta taagcatttt ccaatatttc
    38461 taaatttttt atatctttga gctataattt cctctttatc catatctttg taatgattta
    38521 atctttctaa aatataagct tttatttctt ttgaaacagc ttctacatct ttttgtgctc
    38581 ctccaagagg ttcttttata atcttatcta ttatttttaa atcatataaa tcattacttg
    38641 taagcttcat aacatcacaa gcttctttag ctttagatga atctttaaat agaatactag
    38701 aaagcccttc tggagaaatc acagaataaa ctgaatgttc tagcatacaa acatcatttc
    38761 ctactccgat acctaaagct cctccactac caccttcacc aattacaaaa gtgattactg
    38821 gaacagaaag tttactcatt tcaagtaagt ttcttgcaat agcttctcct tgtcctcttt
    38881 cttctgcttc taaaccacaa aaagctcctg atgtatcaat aaacgttatt ataggtctat
    38941 taaatttttc agcttgtttc ataagtctta atgcttttct gtatccttct ggatgaggca
    39001 ttccaaaatt tctttttata ttttcttttg tatctcttcc tttttggtgt ccaactatag
    39061 taacattaaa ctttcctatc tgaccaatcc ctccaaccat agaagggtca tctttaaaaa
    39121 gcctatctcc atgaagttct aaaaaattag aacaaatatg ttctatgtat tccaatgtcg
    39181 taggtctctt tatatctcta cttagtgtta ccttttcata tgctgataga tgtgaaaaag
    39241 catcttcctt aagcttttcc aatttctcat taagtgaatt tattttatca cttaaatcta
    39301 tattatttgc cttagaaata gttattaatt gtttaatatc attttctaag acttttattt
    39361 tttcactatt attttcaatc aaaacagttc ctcctttatg ccctatttct tgtgcatagc
    39421 aagaatttga tataataatt ccttcatttt tcttctatct actatcatgt caataaaacc
    39481 tttttcaagt aaaaactcag aagtttgaaa tccttcagga agtttttgat ttattgtttg
    39541 ctctattact cttggacctg caaaacctat caacgtattt ggctcagaaa ttataatatc
    39601 accaagcata gcaaaactag cagttactcc tccagtagta gggtcagtta gaactgatat
    39661 atatggcaat gatttttctt caagcttaga aagtgcttga gaagtctttg ccatctgcat
    39721 aagagatacc ataccttctt gcattctagc tcctcctgaa gcagaacaaa taattatagg
    39781 taaattattt tcagcagcat actctattga ataagttatt ttttccccaa caatagaacc
    39841 catacttccc atcataaaat caggattcat tacacaaata actgttttaa ttccatttat
    39901 tcttccataa cctgtgacaa cagcttctga ctcttttgtt ttttccttat aagagtctac
    39961 tttttctttg tatttaggaa aatttagtgg attttgaaat tctacatcag aattaaactc
    40021 cataaaagtt cctttatcaa tcaataaatt tattcttttt cttgctctta agccataatg
    40081 tcttgaacat tttggacata caaatgaatt ttcttctatg tcctttctaa atacatgact
    40141 atcacaacct ttgcaatagg tccaaaattt atcatctaca ctattctttt taaagttgtc
    40201 atctaaagaa atcgtaacat acttagattc ttttgatgat aaaaattttt ttatcataat
    40261 ctatttactc cttataatgt agcaaattct ttcttcataa agacatcttc tataaatttg
    40321 gtatgatgag tatcttctct aaactcctca cttgttacaa gtgccttttg aaattctaca
    40381 tttgtattaa taccttctac aataatttcg tctagagctc tatatattct acttatacat
    40441 tcttctctag tttcagccca acatattaac ttacctatca tagaatcata taaaggtggt
    40501 atagtatatc ctgcatatac aaaagtatca aatctaacac caaaacctcc aggtaaattt
    40561 aatgattcta tcttacctgg tgatggagca aaattctttg atgaatcttc tgcatttatt
    40621 ctacattcaa tagcatgacc tctaaaagta atatcttctt gtttaaaagg aattttatcc
    40681 ccattagcta tagatatttg aagttttata aggtcaagat ttgttaccat ctctgtaact
    40741 ggatgttcaa cttgtattct tgtattcatc tctataaaat aaaagttttt atctttgtca
    40801 actataaact caatagtacc tgcaccgata taacctactc cttttactat atctactgca
    40861 attttatgaa gtttttgtct ttcttcatct gaaaggtatg gacttaaaga ttcttctatt
    40921 actttttgat ttcgcctttg catagaacaa tctctatcac ctaaatgtat tgcatttgaa
    40981 tgtttatctc caaatacttg tacttctata tgtctaggat tttctataaa cttttccata
    41041 tataaatcac tattagaaaa tgctgctaga gcttctgaac ttgccatatc aaaatttgaa
    41101 aaaagttctt cttcttttct aacgattctc ataccttttc caccgcctcc acttgaggct
    41161 tttatcataa caggatatcc aatttctctt gcaacttcta aagcttcttc cttagttttc
    41221 aaaacagatt ctgaaccagg aacaacaggg atattcaatt ccatcatagt ttctcttgct
    41281 ctagatttat ctcccatcaa aatcatttgt tctcttgttg gacctataaa aataatatta
    41341 ttatcttcac attgctttgc aaattcagga ttctctgata agaatccaaa gcctggatga
    41401 atagcatcac actttaattt aagagcaaga tagattatat tttctatatt attataactc
    41461 ttacttatat tatttggtcc tatacaaata gattcatcag ctatatatct atgaaaacaa
    41521 tctttatcta tttcagaata gatagcaaca gtttttatac ctagttcttt acatgttctg
    41581 atgattctaa ctgctatatc gcctctattt gcaactagta ttttttttat caacttaaat
    41641 acctcctact acaatggttt tatcttaaat aaaggttgat tatattctac tagttcttca
    41701 ttactaacta atacttcaat tatttcacct ttaatttcgc ttgttatctc attcataagc
    41761 ttcattgctt ctaatataca taaagtgtcg ccttcttcaa ctacatcgcc aactttaaca
    41821 aagctatctg catctggact tggagaatca tagaatgttc ccatcaaagg agctactact
    41881 actgatagat tctcattaga tgtgacaggt gtatcgttta caactggctt ttctaaagaa
    41941 agatccacta ctgattcttg ttgtacactt aaaacaggtg aacttgtaga ttgagctttt
    42001 ttagatactt ctaatcttaa atcgctactt tcaagtttta catattctaa gttagttgag
    42061 tctatggcct ttaataattc cttaatttca ttgatgttca ttttgttacc cccttgtatt
    42121 attacctggt gctaatatta tatcacaaaa aacaaattta taaaagaaaa agtgctgact
    42181 agagaatcaa cacatcaata tatcttttaa ttttaaatta acaaccagta acttatattt
    42241 gttttaattt tccattatta atataaatta taagtataaa atgaataaaa ttcaatattt
    42301 tttgcaaaat acaagagaat acaaattaat acctcgggaa tttttaagac aaataccaat
    42361 attatgcaat ttagacttcg ctttctttca aattagtatc attttcttta tttttacata
    42421 ggatgtactt taatttagct atcaaaacat tactatatag gttaaaagtt attagaattg
    42481 caggaattat aaagtaaact ctagcaccta taaaaccaaa aactactgta ataagtatta
    42541 atcttttatt taaagtaaaa aaaggtatat taaaaatact tttgtcggat gtttctggag
    42601 tataagaata tataactcca aaaatcaaag taagcataca aagtggaagt agtgtataac
    42661 ttgaaattat tcccagaaat cctatacttt caaaatattt gctagcacta tttgtataaa
    42721 caaacatgta tccatttaaa tatgcgcata tacatgatat aatgccaaaa gttcccccta
    42781 aggattgagt gtaccaatta aaaaatttag attccatata cctcacctcc taaaactgta
    42841 tatataatga tatgcattta aatagtaaaa tatatcttta tatgtttctg aataaaattt
    42901 tgttaatttc attaatttat gtttaagaaa tttgaagtat agtgtagtat atattaatgt
    42961 agatgaagtt ttatagtact tatttcatag tgcttaatca agttatctta ttatggattc
    43021 aaaagttgtt tgtagggttt tatattttgt tgagctgaaa aatttattat aaatgaaggg
    43081 atgttttcgc tttggtagat acattagaat ttggtcttaa aattttattt tttatattat
    43141 caataatttg gatgggtaaa ataatgattt taagaactga taagcaaata gtaatcaatc
    43201 ctttgcttat tggtatatct gcagtccttg tgatgttgca tacctcacag agtaacattg
    43261 aattttttgg attagatgtc caatatataa gaatagtttt gtatataata tattcactga
    43321 taattttaat aggaatatgg gctactaaca gaagaaatgg aattttttag ataatctatt
    43381 tctataaaat ttaaaggttg ctagtaacaa agcactaata ttagcgttct gttactaaca
    43441 acctttattt tgattataca cttaaattga aaatagaatg attgaataag ttgacatatt
    43501 attttacatt gacagtgatt agaacttctt gagatgtatt taaatcattt ttgtcgctta
    43561 gtataacttt taccacagct tgacctgttt tattaccttt aattatcata tcttcacatg
    43621 aaagtacact cttatcactt acagatacaa taaagtctaa atcttttgga agattatcag
    43681 taacttccca gtatttataa taactatcaa ttttcttcgt aattattttt ctcaaatcaa
    43741 tactttcacc ttttgctata tcaacattat gatatttaga gtccagttta tactgattat
    43801 cttttgtatc aataaaattt aaatcgcaat ttacatccac accattatga gaaagagaat
    43861 ttactacatc gtcatcaatc aaataattat tggcaagatt tattgaatcc atatctttta
    43921 gacttaaagc ttccttagga acctctttta tattattatt ccaaaaaata aaattgtcta
    43981 cattttcaag atatgatatt ccttttaaat ttgaaatgct ctcaccagtt gcataaaatt
    44041 ctccatctaa agcctttata ttgcttatag tcatctcatc tgggtttata tatcttttta
    44101 caactgctct taaatttgca tcaggaaaaa tatctttaag ttgattttcg ctcaaaacct
    44161 tatcatttga atttattgga cttaaagctg ctgcagaaat aataaatggt attaaattag
    44221 ctaaattcat agtaccctcc cacataaatt ttttattata ataatttaat ttctatgaga
    44281 gggttctgtt tccttgttat atatacctac tttcgtacac tttattaata taaattaaaa
    44341 taaatttcta ctattaaact tataaacata ttactagtta cgttttttag cttcacatct
    44401 aaatattcgc ataccttgtg acataaattt gtcttcatac tctgttgtaa cattattttc
    44461 atactcacta tttcctaaat caagagaaat attctttaat agccaattat ttgcagcaat
    44521 ttcatttaaa ctaaactcga ataatttttc attatctgtt ttaaagtgaa tttcgccatc
    44581 atcttccaaa accctattgt acatttctaa aaatccagaa tgagtgagtc ttcttttact
    44641 ccatctattt ttaggccatg ggtcacagaa atttatataa attctcgata attctttagc
    44701 ttcaaagtaa tccaaaatat tgcttacatc tccccataaa aatagtatat tattcaaatt
    44761 agaagcatct gctttttcaa cagcttttaa aagaacttct tccttaagtt ccatggcaat
    44821 ataatttatg tcagggttct gcttagctaa agttgttata aacttacctt ttccagtccc
    44881 aaattcaaca tgtattggat tatcatttct aaactttaaa ttccacttgc cttttaattt
    44941 gtctatatcg tctcttaaaa catattttgt ataacttaaa agcttttcat ctgcaccttt
    45001 ttttcgtctt cttctcacaa taattctcct tacatataaa aaattagtaa aatacatttt
    45061 tattatacat tatctcacca aaaaataaaa agaactctct taaaatagaa atttatttct
    45121 ataaagagag ttctaaactt actaaaaact taatcttagt ggcaccctga acaaccagag
    45181 catcctcctc caccttgatc tttcatattt tcaggaataa ctctaaatcc aaatcctgta
    45241 tcttctatta ttatatctcc atactgacta tattcatcag agctcattac aaattgtaat
    45301 tctccaactt cataagttaa gtcatcttct tttttctcat ctaaagctaa tccaaaagaa
    45361 ggacctccac aaccaacacc tgcaaagtat actcttatat tattaggttt atcttgattg
    45421 tcttttaaga tactttttaa agtatcaata gctgtttctg gtaaagtaat tttcatcaaa
    45481 tcattccctt tcaaatattt tattaaaaca atatctatta tatacccata caaggtacat
    45541 aatcaattag tttttgcata ttttactaaa acttctacct aatattacct aaggctttaa
    45601 aatattttat ataatatttt attaccttaa ataaataccc tatcat
//
LOCUS       DAMJWO010000025        45576 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.026, whole genome shotgun sequence.
ACCESSION   DAMJWO010000025 DAMJWO010000000
VERSION     DAMJWO010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45576
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.026"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            88..747
                     /gene="cprR"
                     /locus_tag="PC366_001421"
     CDS             88..747
                     /gene="cprR"
                     /locus_tag="PC366_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HDF2576952.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
     gene            958..2016
                     /locus_tag="PC366_001422"
     CDS             958..2016
                     /locus_tag="PC366_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF2576953.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPKKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            2267..4411
                     /gene="fdhF"
                     /locus_tag="PC366_001423"
     CDS             2267..4411
                     /gene="fdhF"
                     /locus_tag="PC366_001423"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:2681..2683,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HDF2576954.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKTWGVKLSPNNGYSLTQVPDLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            4460..5293
                     /gene="fdhD"
                     /locus_tag="PC366_001424"
     CDS             4460..5293
                     /gene="fdhD"
                     /locus_tag="PC366_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HDF2576955.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNDKYVNTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNSLDYITCASVKSNIKINYDTIYSIMDRNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            5304..5477
                     /locus_tag="PC366_001425"
     CDS             5304..5477
                     /locus_tag="PC366_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576956.1"
                     /translation="MCTKKEEQKCSKCEICGVLIDDTDKVYNNTYNLCKKCKRNISTE
                     KIVKYINIYDESK"
     gene            5535..6086
                     /locus_tag="PC366_001426"
     CDS             5535..6086
                     /locus_tag="PC366_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2576957.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRHCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            6111..7487
                     /locus_tag="PC366_001427"
     CDS             6111..7487
                     /locus_tag="PC366_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HDF2576958.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            7487..8002
                     /locus_tag="PC366_001428"
     CDS             7487..8002
                     /locus_tag="PC366_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2576959.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNPDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(8080..9363)
                     /locus_tag="PC366_001429"
     CDS             complement(8080..9363)
                     /locus_tag="PC366_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugated bile salt MFS transporter"
                     /protein_id="HDF2576960.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSHSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     TISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKKLNKERLDKLMQ"
     gene            9551..9973
                     /locus_tag="PC366_001430"
     CDS             9551..9973
                     /locus_tag="PC366_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HDF2576961.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSEKNGENIIRDILDGNISSECENGIKSKSVIFNNTPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            10075..11013
                     /locus_tag="PC366_001431"
     CDS             10075..11013
                     /locus_tag="PC366_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDF2576962.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYIMENKPVDNVVDISRGY"
     gene            11199..13223
                     /gene="ligA"
                     /locus_tag="PC366_001432"
     CDS             11199..13223
                     /gene="ligA"
                     /locus_tag="PC366_001432"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HDF2576963.1"
                     /translation="MSVKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKDMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKANDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            13383..14732
                     /gene="rph"
                     /locus_tag="PC366_001433"
     CDS             13383..14732
                     /gene="rph"
                     /locus_tag="PC366_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HDF2576964.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRAIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKTIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEIADEILGMDYGNEVVIATNNAHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARAIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNVPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            14732..15202
                     /locus_tag="PC366_001434"
     CDS             14732..15202
                     /locus_tag="PC366_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2576965.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTNMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDDIKIEEIRI"
     gene            15396..16682
                     /locus_tag="PC366_001435"
     CDS             15396..16682
                     /locus_tag="PC366_001435"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HDF2576966.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            16831..17415
                     /gene="clpP"
                     /locus_tag="PC366_001436"
     CDS             16831..17415
                     /gene="clpP"
                     /locus_tag="PC366_001436"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDF2576967.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            17434..18684
                     /gene="clpX"
                     /locus_tag="PC366_001437"
     CDS             17434..18684
                     /gene="clpX"
                     /locus_tag="PC366_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HDF2576968.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(18755..19282)
                     /locus_tag="PC366_001438"
     CDS             complement(18755..19282)
                     /locus_tag="PC366_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF2576969.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(19270..19782)
                     /locus_tag="PC366_001439"
     CDS             complement(19270..19782)
                     /locus_tag="PC366_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF2576970.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            19962..22325
                     /gene="lon"
                     /locus_tag="PC366_001440"
     CDS             19962..22325
                     /gene="lon"
                     /locus_tag="PC366_001440"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HDF2576971.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFNSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLGNIPRPLLDRMEVIEVSGYIEEEKLNI
                     ARKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTAVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            22315..22926
                     /locus_tag="PC366_001441"
     CDS             22315..22926
                     /locus_tag="PC366_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HDF2576972.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(23191..24561)
                     /locus_tag="PC366_001442"
     CDS             complement(23191..24561)
                     /locus_tag="PC366_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2576973.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYALGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDISGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFIGLILTVFFMRK
                     TDKSIS"
     regulatory      complement(24736..24851)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            25139..26218
                     /locus_tag="PC366_001443"
     CDS             25139..26218
                     /locus_tag="PC366_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2576974.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKATEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     gene            26610..27290
                     /locus_tag="PC366_001444"
     CDS             26610..27290
                     /locus_tag="PC366_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF2576975.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSEEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            27283..28662
                     /locus_tag="PC366_001445"
     CDS             27283..28662
                     /locus_tag="PC366_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HDF2576976.1"
                     /translation="MINIILEESSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGVLLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            28833..29918
                     /locus_tag="PC366_001446"
     CDS             28833..29918
                     /locus_tag="PC366_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HDF2576977.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKVKNLLSIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISTVVTNNLAYIIFSFILFSIGSIYFFITNDNIKKLINSLKFKIPF
                     IKKINQLVATTRFSRALSVLISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANVFPKLFISMANTGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            29972..30331
                     /locus_tag="PC366_001447"
     CDS             29972..30331
                     /locus_tag="PC366_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HDF2576978.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            30384..31256
                     /locus_tag="PC366_001448"
     CDS             30384..31256
                     /locus_tag="PC366_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HDF2576979.1"
                     /translation="MAIIKKILNLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIVIRNVEVLNTKKKRDI
                     LSMIEFEITQYIPININNYSIKYKVINSKNDKLNIQVILFPKSIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIRETYLLSKEGK
                     SYEFIKRLLRDFKYVYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNFDADLE
                     DNRINYINSIGMII"
     gene            31257..31700
                     /locus_tag="PC366_001449"
     CDS             31257..31700
                     /locus_tag="PC366_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576980.1"
                     /translation="MKVDKTINFLNGFKKTKPCNKIYKIIIVLILTCILFKSFMYVKS
                     INELEDYINQNKLVDKSKHTLPTTDKTREKFSKIKLNEIKKIYETIGINSITKISIDK
                     NKLEMEGVCSDLDVLNNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            31715..32299
                     /locus_tag="PC366_001450"
     CDS             31715..32299
                     /locus_tag="PC366_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576981.1"
                     /translation="MRLNNREKNLLKILLILVIILASDIAVSYLEENLTSLKNEKQNI
                     INKINNQDNYQIKDNKHIDDKYIESVELNKNEELKNNFNNSFLDKKTNKDIVLLVENE
                     LRDIVNVEYINQESSLDNHNKKQVNLEIKVNGELANVLKLEGVMKKLRLNNKLEKIEI
                     NKLKVNNFDVQNIPNEYKQEKDNIVECKMTVRVI"
     gene            32552..33589
                     /locus_tag="PC366_001451"
     CDS             32552..33589
                     /locus_tag="PC366_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HDF2576982.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLSGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            33670..34035
                     /locus_tag="PC366_001452"
     CDS             33670..34035
                     /locus_tag="PC366_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576983.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINVAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            34040..34357
                     /locus_tag="PC366_001453"
     CDS             34040..34357
                     /locus_tag="PC366_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576984.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            34405..36009
                     /locus_tag="PC366_001454"
     CDS             34405..36009
                     /locus_tag="PC366_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2576985.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVVLKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYINVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            36133..37761
                     /locus_tag="PC366_001455"
     CDS             36133..37761
                     /locus_tag="PC366_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HDF2576986.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTNLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIAKTYRRERLINDLQKAILNYLL
                     KLSKAPLDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNISFSEEGQSELD
                     VMYNRVVSAYTYALESMRTDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            38026..39375
                     /locus_tag="PC366_001456"
     CDS             38026..39375
                     /locus_tag="PC366_001456"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HDF2576987.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSAEKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            39531..40610
                     /locus_tag="PC366_001457"
     CDS             39531..40610
                     /locus_tag="PC366_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDF2576988.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
     gene            40955..41863
                     /locus_tag="PC366_001458"
     CDS             40955..41863
                     /locus_tag="PC366_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HDF2576989.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGVNIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
     gene            41868..44237
                     /locus_tag="PC366_001459"
     CDS             41868..44237
                     /locus_tag="PC366_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HDF2576990.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKKDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFQSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRLTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPKDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            44562..45365
                     /gene="proC"
                     /locus_tag="PC366_001460"
     CDS             44562..45365
                     /gene="proC"
                     /locus_tag="PC366_001460"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDF2576991.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAEDITVSDLSQVALDKV
                     KEEFGINTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
BASE COUNT        18707 a         4833 c         8260 g        13776 t
ORIGIN      
        1 gagagtatta tggttaatgt gaattttaaa gatattatta aagatataaa ttagaatact
       61 attaaacgga taaatggagg agttattatg tctaagatat tagtagtaga tgatgagtta
      121 gatatgttaa agttgattga aaatgtgttg aaaagagatg gacatgaagt aaaggtaatt
      181 agtgatgtag aaaaggctat gaacatggat tttaattatt ttaatctaat aatattagat
      241 gttatgatgc ctaagatgga tggttttgaa gtatgtaaaa ctataagaaa taaggttgat
      301 tgtccaatac tgtttttgac agcaaaaaat atggaaagtg atattatgta cggtcttggc
      361 ataggtgcag atgactatat aaccaaacct tttggtgtag gagaattaag ggctaggata
      421 actgctcatt taaggcgaga aagtagagaa aaaaagaatt tattaactat ctcaaatgtt
      481 caatttaact ttttaggcaa agaagtttca attgatggta aaaaaattaa ttttactaaa
      541 agtgaatatc taatatgtga atttctagca aaaaataagg gacaagtatt ttcaaaagaa
      601 agaatatatg agtcggtata tggttttgat ggagaaagtg atataagtac tatcacagag
      661 catataaaaa atatacgaag caaattaaaa caatatgata tttatacaat agaaactgta
      721 tgggggatag ggtataaatg ggtgtaataa gtataagtgt tgcttagtga aaatattata
      781 tatatctaca aaatgtttgt aaaatattaa tctatatatt aaaatttaat ttatagatta
      841 atattttttg taaatgacaa aattgtaagg tattttgtta taaaatatta agattcatag
      901 tgtatactaa taatatagta tttagtataa atcttgagca aaggatggtt atttctaatg
      961 gatagactaa agaatattag aaagagttta ctacagtata catttttatt tttgttaata
     1021 ggtataacaa tttacctagt gtttaaaaca ttggatatta aaatgctatc aaatgttatg
     1081 gttatggtag ataagaagtt tttattcata ggtgctttgg caataatgtg tcacataatg
     1141 cttgaaggag tagtaatgaa gataattata gaaagcactc acaaagttaa tattagattt
     1201 attggtttta agctagccat tatgggattt tattataatt taataactcc ttttgcttca
     1261 ggaagccaac cagtacagat atatgtactt aaaaaatgta aaatgccact tagtaaggca
     1321 agtgcagttg ttaccaataa gtctattatt ttccaaatag tggttacttt ttattgtaca
     1381 atacttgtat taatgaattt tgctatgtta gaaaaacaaa tgaaaatgat tatgcctcta
     1441 gtgtttctag ggatagccat taattcattt gtcttaatta tgataatatt agttatttta
     1501 aaccctaaaa aaataaaata ttttatgaga attactataa agcatttatc aaaaattaag
     1561 tttttaaaat ttttagataa taagattgaa tccatagaaa gttttataga tgattatagt
     1621 aaagcaataa atttttttgc aaagaataaa aaggtattaa tttcaactat aatagtaact
     1681 tttattcaat taagtgctta ctttagtgtt tcattttgga tatataaagc atttaattta
     1741 caaggttata gctatattta tatactgaca ttacaagcat ttttatatat ggcaatatct
     1801 ccaataccaa cacctgggaa tgtaggagct aatgaattag cctttttcac tatattcaaa
     1861 tcagtattcc ctcaaccttt gatgggatat gcagtatttt tatatggtgg atttatgtac
     1921 tatttaattc tgattggaag tggaatattt actgtaatta ctcactatag aatgaaaaat
     1981 agaattggca gaaatattgt tttaagtgaa aactaaataa gtttaaagaa tatatattga
     2041 gtatattaaa aaatatgtca taagaactag aatattttaa ttaaatggtt gaaatataaa
     2101 gattattatg acatattttt tttgaaattt aagaggaatt gtgagaaaat tgttgaattt
     2161 aatagatagt attgcaaaat atttatgatt ttgcatatta taaaaacact cattatcttt
     2221 aagataaatt ttacttatca ggggataaat ctaagggggg aattgtatgg agaaaaaaat
     2281 tttaacagtt tgtccatact gtggagctgg atgccaatta tatctagtag taaaagataa
     2341 taagatatta agagctgaac cggctaatgg tagaacaaat caagaaagtt tgtgtttaaa
     2401 aggtcgttat ggatgggatt ttctaaatga ccctaaaatt ctaacaccta ggctaaaaaa
     2461 gccaatgata agaaaacaag gtgtactaga agaggttgaa tgggatgagg ctataaacta
     2521 tacagcttca agactaaatg aaattaaaga aaaatatgga cctgattcta ttatgggaac
     2581 aggttctgca agaggacctg gtaatgaagc aaactatata atgcaaaaat ttatgagagc
     2641 tacaatagga actaataatg ttgaccattg tgctcgtgta tgacatgcac catctgtagc
     2701 cggtctggct tactcattag gtagtggtgc aatgtctaat tctataccag agatagaaaa
     2761 tgcagatgtt ttatttatat ttggatataa tggagcagat tcacatccaa tagtggcaaa
     2821 tagaatagta aaagctaaaa aaaatggtgc taaattaatt gttactgacc ctagagtaac
     2881 tgaatctgca agaattgctg atatacatct acctataaaa ggtggaacaa acatggtttt
     2941 agtaaatgct tttggaaatg tattaataga agaaggtctt tacaataaag aatttgttca
     3001 aaatcataca caaggatttg atgagtataa agaaattgtt aaaccatata cagctaaata
     3061 tgctgaaaag attacaggaa tcccagaaga gcttataaga aaagctatga gagaatatgc
     3121 aaaagggaaa aaagctatga tactttatgg aatgggtgtc tgtcaatttg gtcaagctgt
     3181 tgatgtagtt aagggacttg catcaattgc tctacttaca ggtaattttg gtagagaaag
     3241 cgttggaata ggacctgtac gtggacaaaa taatgttcaa ggagcttgtg atatgggagc
     3301 tcttcctaat gtatatcctg gctatcaaaa tgtaactgat gataagataa gagaaaagtt
     3361 tgaaaaaact tggggggtaa aattatctcc taataatggt tatagtttaa ctcaagttcc
     3421 agacttagta ctaaaagaga aaaagcttaa agcttattat atatttggag aagacccagt
     3481 gcaaagtgac ccagatgcat cagaagttag agaagcatta gatgaattgg aatttgtcat
     3541 tgttcaagat atatttatga ataagacagc acttcacgct gatgttatac ttccagctac
     3601 ttcttgggga gaacatgagg gagtatatac atgtgcagat agaggattcc aattgatgag
     3661 aaaagctata gagccacaag gagatgtaaa accagactgg caaattataa gcgaaatttc
     3721 tacagcaatg ggatatccta tgaattataa aaatactaag gaaatatggg acgaacttag
     3781 acaattatgt ccaagtttct taggtgctac ttatgaaaag atagaaactc aaggatgcgt
     3841 tcaatggcct tgtaagagtg aaagtatgga agataaagga actatgtatc tgtatgaagg
     3901 tcaaaagttt tctactccta atggtaaagg taatttgttc gctgctgaat ggagaccccc
     3961 tatggaagtt gaagatgatg aatacccatt tagtttatgt actgtaagag aagttggaca
     4021 ctattcagta agaacaatga ctggtaattg tagaacactt agttcattag aagatgaacc
     4081 aggacgtgtt caaataaatt ctaatgatgc tgaaaaatta ggaattgaag atgatgaatt
     4141 agttagaatt agttcaagaa gaggaagtgt aataacaaga gcaacagtta ctgatagagt
     4201 taaggaaggt gcaacatata tgacttatca gtggtgggtt ggagcttgca atgaacttac
     4261 aatagcaaat ttagacccta tatctaaaac accagagtat aaatattgtg ctgttaaact
     4321 tgaaaaactt gaagaccaag aattagcaga aaaatgtgta agagaagagt atcaaagttt
     4381 gaaagacaaa atgacagcta caaatatcta atgatttatt agatttaaga tttataaaag
     4441 gcagaaaggc taatatttta tgaacaatat atactcaaaa actaaattac aagaaaatag
     4501 taaggataaa gtttttgaaa atagttatag tctagtggac tacaaatatt taaattcttt
     4561 taatgtagaa gtaagcaaaa taaatgaaca tgaagtatca atagataatg aagaaataat
     4621 tgcagaatat ccacttagtt ttattttaaa tgataaatat gtaaatacat ttttatgtac
     4681 cccatataat ttagaggaac ttatagtagg attcttgaaa acaaaaggat acatagaaaa
     4741 caaaaaaagc ttattaaaat ttgagataaa tgagagtgaa cgttttgcaa aagtaactat
     4801 tcaagagaaa caaaaaaatc aagatgagca aattatattt ttaaattcac tagactatat
     4861 aacatgtgct tctgtaaaga gcaatataaa aataaattat gatacgattt acagtataat
     4921 ggatagaaat ttaaattcat cagaattatt taaaaatact ggtggggtac atagcgtatc
     4981 tgtatttaat tttgataaaa aaatagtcac ttgtgaagat gtagcaaggc ataatgcaat
     5041 ggataaggct attggatttt gtgttttaaa tgacataaca ttaaaagata aaattgtggc
     5101 tgtaagtgga agaatatcat tggaaatgat attaaaagca gctatgactc aaattcctat
     5161 tgtagtatca aaatcagcac cgactaattt atcaatagag ctttctaaaa aattaaatat
     5221 aacgcttatt ggatttgtaa gaggaagacg gatgaatatt tatgcaaatc cacagagagt
     5281 tatcaaaaag tgagaataag tatatgtgta ctaaaaaaga agaacaaaaa tgttcaaagt
     5341 gtgaaatctg tggagtatta attgacgata ctgataaggt gtataataac acatacaatt
     5401 tgtgcaaaaa atgtaaacga aatataagta ctgagaaaat agtgaaatat ataaatatat
     5461 atgatgaaag taagtagaca tatgatgaaa gtaactagag ggttggaaat atacaaattg
     5521 aaaggtggga taatatgaaa aataaaatag gctcttttgt aatagcggac ccaaacaaat
     5581 gtacaggttg tagagcttgt gaagtagctt gttttacaat gcataatcag cataataatg
     5641 tgggttatac agttggaaca gttgatatac ctgttatacc tagactttat ttagtaaaag
     5701 gtgacaattt ctgtatgcca atacagtgta gacattgtga agatgctcct tgtttaaact
     5761 catgtccaca aaaagctata gtcaaagaaa acaatattat gtctgtaaat gaagaaaagt
     5821 gtataggatg taaaacttgt ctgctagcat gtccttttgg agctatagac ttacttccac
     5881 aatatgaaga tggtaaagaa gtagaacaag taattttaga tgaaaataag aagatagctt
     5941 ataaatgtga cttatgtaaa gacaatgaaa aaatagcttg tataagtgca tgtcctcagg
     6001 aagcattaaa acttgttact ccaatagatg acaaaaaagc taagaataga caagctgcac
     6061 ttagtttatt gttaacaaat aaataaagga tacaggggta ggtgacgttt atgataataa
     6121 atatagataa ggatttatgt actggatgta gagaatgttc aaaggtctgt ccagtaaatg
     6181 ctattgaagg tgaagaggga aagccacaag agataaattt agatagatgt gttatgtgcg
     6241 gtcaatgtgt tcaaacttgt aaatcttatg cctcagttat agatgaagga tttgagtttt
     6301 tacaagagaa aaaacaagaa agagagatac cagagtctat aaatgaacct atatttgcag
     6361 catacaatgt atgtgatata gataaggtaa agaaagcttt aagtgaccca aatgtattca
     6421 ctatggtcca atgtgcacca gcagttagag ttgctttagg agaagatttc ggatattatt
     6481 taggatactt aggtgctgga aaaatggcag cagcacttag agctttaaat tttgatagag
     6541 tctacgatac taattttgca gcagatttaa ctataatgga agaaggtagt gaattaatta
     6601 aaagagtgac agaaggtgga actcttccaa tgtttacatc ttgttgtcca gcttgggtaa
     6661 aattcatgga aaaaaattat cctaaattaa ctaatcattt atcttcttgt aaatcacctc
     6721 agcagatggg tggtgcaata tttaaaactt atggtgcaga gataaataat gtagatgcat
     6781 caaagatatt tagtgtttct ataatgccat gtacatgtaa aaaatatgaa tgtgatagag
     6841 aagaaatgga ttctagtgga tatagagatg tagatgtagt attaactact agagaactag
     6901 cttatttaat aaaagacatg ggaattgatt ttaaaaattt aagagaagaa aaatttgata
     6961 gtcctttagg tagttatagt ggagctggaa ctatctttgg tgttactggt ggggttatgg
     7021 aagctgctat aagaacagga tatgagctta taactggaga aagtattcct gatgtagaag
     7081 taaaacaagt aagaggagaa aatggtttta gaaagtcaac tattaaaata ggagacttag
     7141 acttaagagt tggagtagta agtggattaa aaaatgtaat accagtgctt gaagacttgg
     7201 aaaaaggaaa attagatgta gattttattg aagttatgac ttgtcctgtt gggtgtgtaa
     7261 gtggtggagg tcaaccaaaa attttactag aagaatataa ggaattggct tatgaaaata
     7321 gaacaaaagc aacatacgtg catgatgaac atttagcaat tagaaaatct catgagaatc
     7381 ctgatattaa aaaactgtat gatgaatatc tggtagaacc attaggagaa aaatctcatc
     7441 atctattaca cactacatat tgtataggaa aggaagtggc taagtgatga actattttgt
     7501 tatagcagac cctgataaat gcataggatg tagaacttgt atgataggat gtgtagttgc
     7561 acattcagat gaagatattt tttaccaaaa tccagatgaa ataaatttta atccaaaact
     7621 ttctgtcata aagacaaaag aagtaagtgc tccaatacag tgtagacatt gtgaagatgc
     7681 tccttgtgca aaggcatgtc caaatggtgg tatagttagg gttgggaaca caataaaaat
     7741 aaatgaagaa aattgtatag gatgtaagac ttgtatgtta gcatgtccta taggtgcaat
     7801 agacatagtt acattaaaag atgtagatga aggaaagctt tgctttagag aaagaatgac
     7861 agcaaataag tgtgattttt gtatagaatc gccagaaggg cctgcatgtg taaatgtttg
     7921 tccaactaag gcatttacta tagttaagga tgaggatata gatagtaaag ttaaaaataa
     7981 gagaaaatta gctatattgt aatataaaaa agatggagtt ttatttatga ttaaaagctc
     8041 catctttttt attataatat ttatatatct aaaaatcaat tattgcatta gtttatctaa
     8101 tctttcttta ttcaattttt tcattcctat agaagttata ataagtaaag tataggcaat
     8161 tataactgat aaaattataa tagaccaaga aaatctgtat ccaaaattat caactaacaa
     8221 tccaaataat gttgaaccta atgcaaatcc cactgcaaaa attaattgta cgattccata
     8281 tatgctacca aactcctttt gaccaaagaa agagccagtt aaataagcag gaccaatcat
     8341 ataagcaaat acagaaagac ctttcaaaat ggcaaataca aatgcaaaag tagaagattt
     8401 atctaccaat agtaatgata aagttgctat aagaaccaat acaaaagata taataagtgg
     8461 ctttgtttga ccgaatttat caaacaataa tcctccaaat aaattaccaa tgagagcaaa
     8521 taaagcaaat gtggagccta ctgttcctat tagaatagga tttagataat ttctaagata
     8581 agttggatat tgtacggata atgatgaaac atatatacca acaaatataa atccaatagt
     8641 cataatccaa aaatatttaa tttttttagc ttcttttaat gtataacccc atactgaagg
     8701 agaaattgta tcagatgctt tctctttttt acctttagat tttacctttt cattaatatc
     8761 tttaggcatc ctgagtatga ataatattac aggtatacca actattaatg ctataattcc
     8821 aaatattaga taagaatgac tgtatccttg agttgctaat aagcgaactg caagtggttg
     8881 tagaaatata ctaccaatag aaccaccagc aaaagcaaag cccaaagctt ttcctttgct
     8941 ttcttcatca aaccaagcac ttattaaaac aggtattcct atagcagata taattgtagc
     9001 gccaatttga acaatacatg atacagtgta aaattgccat agttcagtac atatagaaaa
     9061 agtagcaaaa gcaatactag aaattataca acctaataaa tatagtatct taatattgac
     9121 tttagaaaat aatacaccta taaaaggtga tgcaattgct gaggcaatag taccaatagt
     9181 gaatattaga gaaaaagaag ctaaactaaa gccttctcct tctacaacat aacttataaa
     9241 ttgaggctgt atacttgcta caatactaaa tggaacagct tgtattaaca tacaaccaag
     9301 tactataacc caagcatttg aaaagttttt aatgctaaat ttattgttta gtaatgtatt
     9361 catggtatct ctcctttagg ttatgatttg tagatattaa tctaattatt ctaattttat
     9421 atattagttt tggatagcct aactatttaa atgtaatttg ggtattaata taaaaattaa
     9481 ctataaaaat tgattatttt aaatgtatgg ggtaaattaa agtatataaa taaatgaaag
     9541 gatggataaa atgtcatttg aaaaaataaa taataataac ctagataaaa tacacaatag
     9601 gaagtgtatt atgcttgtaa actttaataa aaaagaatta tcattaatta aaaacgtaag
     9661 taactttgct ggaataagag accatataat cttaagtgaa aaaaacggag agaatataat
     9721 aagagacatt ttagatggaa atatatcaag tgaatgtgaa aatgggatta agagtaagtc
     9781 tgtaatattt aataacactc caagcacaca agtaaatgca tttttagaag gtctaaaaaa
     9841 agtgagaata aatagacctt ttacagctat ggtaacagag acatctattg attggacatt
     9901 gaataattta atagaaaatt tagttcaaga acgtaatgct atgtctttag gaaaaacaat
     9961 tgaacataag taaatttaag atatcttata gtaattttaa ctaatgtaca ttgagtatca
    10021 tattatattt tagaatataa aattttaaat gtgggtagat agaggagatt tgagatgaaa
    10081 gttttattta caataaatta tggaaaagaa aaatttgata aaataagaga attaggctat
    10141 gatgtcatac attactctga agatagtatt gaaaataatg aggatgtaaa tacagcagat
    10201 gtactagtta catacaatcc atttgagaga ttagatattt ctaagatgaa aaatttacaa
    10261 tatatacaga caactagtgt aggtatagac caacttccaa aagaagaggt attgaagaga
    10321 aatattaaga tagctaataa tagaggcgga tatagtgtac ctattggtga aagtattgta
    10381 ttgtatattt tagaaatata taaaaatagt gcaaaatttt ttaaacaaca acaaaataaa
    10441 gaatggaaga tggatttttc tgtatcagaa ttgtatggac aaagagttgg atttttagga
    10501 acaggtacta tatcttcaga agcagcaaaa cgattaaaag cttttggtgt agaaatatgg
    10561 ggtgtcaata ctgatggaag tagtaaaaaa tactttgata agtgttttgc tactgaagat
    10621 atgaatattg tatttgaaga atgtgatata gtagttgtag caatgccttc tacaaaaagt
    10681 acagatggaa tagtaaacaa agatatgttt aaacttatga aagatggttc tgtatttata
    10741 aatgtaggta gaggaaatac agttaatcag aaagatttag aagaatgtgt agagaaattt
    10801 agaggggtag cactagacgt atttgaaagt gaacctttaa acaaggacaa taagttgtgg
    10861 gagtgcgaaa atgtcatagt aactcctcat aattcttggg tgtcagataa aaacaaagag
    10921 agaacattta atatggttta taataatttg aaacactata taatggagaa taaacctgta
    10981 gataatgttg tagacatatc aagaggctat taaaaataaa aaattttgat aaaaataaaa
    11041 actcttatta gtcgtattaa agatactaat aagagttttt tttgtaataa atttaaagtc
    11101 aaaaaagtga tatactaaaa aatatataaa taggagataa ttaattatag ggaaatttca
    11161 aaataattta attttaaaaa tatgaagagg tgcaaaaagt gagcgtaaaa gatgaaatta
    11221 ataaacttat agagacaata aactaccata atgaaaggta ttataatcaa gatagcccag
    11281 aaatatcaga ttatgaatac gataagttaa tgaaggagtt aatttcttta gaagaagaac
    11341 atccagaact aaagagaatt gattctccaa caaatagggt aggaggtaag ccattagata
    11401 aattcaatca aattgtacat aaaactccta tgttgagttt atcaaatgct ttttcagagc
    11461 aagatttgag agattttgat aagagagttc aagaatatgt gggagaaaat gttgaatatg
    11521 ttgttgaatt taaaatagat ggtctttctg taggtctaac ttataacaat ggagagtttg
    11581 aaaaaggagc aactagagga gatggagttg taggagaaga tatttctcaa aacttaatga
    11641 cagtaaaaag catacctctt aagataaatg ataaaaaaga actaatagtt agaggagaag
    11701 tatatatatc aaaagataat tttagaaaag taaatgaaca acaagaagaa caagaacagc
    11761 cattatttgc taatccaagg aatcttgcag ctggttcatt gagacaatta gacccaaaac
    11821 taacagcaaa gagaccatta gatatatttg tatttaatat ggaaaatata gaagaatatg
    11881 atttagaaag tcacagtgaa tcactagagt acttagaaaa actaggattt tcagtaagtc
    11941 agagttataa agtttgtaaa agtatagatg aagttattga gcatattgaa tactggacag
    12001 ataacagggg taatttagac tacgaaatag atggtatggt aataaaagta aacaatataa
    12061 aacaaagaga cgaaatggga tatacagcca aaagtcctag atgggcaatt gcatataaat
    12121 tcccagcaga aaagaagaaa actaaaatag tagatataat agtagaagtt gggagaactg
    12181 gtacaataac accttcagca attcttgaac cagtcagact tgcaggtact actgtaagta
    12241 gagctacact tcacaatgaa gattatataa gagaaaaaga tataaaaata aatgatacag
    12301 tattagttca aaaagcaggg gacataatac ctcaagtttt agaagttata aaagaggaac
    12361 gtactggaga tgaaatagat tttaaaatgc cagaaaagtg tccagtttgt tcagagccaa
    12421 caataagatt agaaggagag gctgctgtaa aatgtatcaa tatgtcttgc ccagcccaaa
    12481 taagaagggg aattatacac tttgtgtcaa gggatgcaat gaatatagat ggattgggag
    12541 aatctataat tacactgcta ttaaatgaaa aaattattca agatgtatct gatttatatt
    12601 atataaaaaa ggaagatgta gtcgacctag agagaatggg cgaaaaatct gctgacaatt
    12661 taataaattc aattgaaaaa tcaaaagaaa atgatttatg gagacttata aatggattag
    12721 gtattaaatt tataggagtt aaagcagcta agatacttgc atataacttt aaggatttag
    12781 atgaagtaat ttctgcaact agtgagcaac tagaagaatt agaggaattt ggaagtataa
    12841 tggcaaacag cgttgtcgag ttttttaagg aagacaaaaa tatgaacgtt ataaacaagt
    12901 taaaaaatgt aggagtaaat acaaaatcat tggataatac aggtgaaaaa gtagaaaaaa
    12961 tatttgaagg gatgaaaatc gtattgactg gtacacttcc tacattaaaa agaaatgatg
    13021 cgaaagatat gatagaaaaa agaggtggaa aagctacatc tagtgttagt aaatcgacaa
    13081 catttgtttt ggcaggtgaa gaagctggtt ctaaacttac taaagcaaat gatttaggaa
    13141 ttaaagttat agatgaagag agatttttag aattattaaa gttatcatcg aaagatgaag
    13201 taaaagctgt attagagagt taaaaagtcg cttaatttag tagaaaacta ctataattaa
    13261 tgatagaata gttcagtaag ctaataagat tacgaaaaat gacaataatt aatatttgac
    13321 aaaattaaaa attataaaaa taaatttata aaaaataaaa aatatgagaa aggatataaa
    13381 aaatgaccag aagttatgat agaagtaacg aacagataag acctgtaaag ataactagag
    13441 attatacaaa gtatgcagaa ggttctgttc ttatagaaat gggagagaca aaggttatat
    13501 gcactgcatc agtggaagaa aaagttcctc cttttttaag aaatagtggt actggatgga
    13561 taaatgctga atattctatg ctaccaagag caacacaaca aagaaagata agagatgcat
    13621 ctaggggaaa aattgatgga agaacacaag aaatacagag gttaatagga agagcaataa
    13681 ggtctgttgt agacttgaat aaattaggag aaagaactat ttgggtagat tgtgatgtga
    13741 ttcaggcaga tggtggaact agaactgcat ctataacagg ggcatttgta gcagttgcag
    13801 aagcaatata taaattatat aaagcaaaga caataaaaga gatgccaata acaaattttg
    13861 tatctgcaat tagtgttggt attgtaaatg gaatacacat gctagattta tgttatgaag
    13921 aagattctaa agcacaggta gatatgaata taataatgac tgataagtgt gagtttgtag
    13981 aagtacaggg gacaggagaa gagaaacctt tttcaagagc agatttaaat ttattgttag
    14041 agttaggcga aaaagggaat aaagaattaa taaggcttca aagagaagct ttaggtgaaa
    14101 tagcagatga gatattgggt atggattatg gtaatgaagt agtgattgct actaataatg
    14161 ctcataagct agaagaaata ggtgaaatct taaaagattt tgaatataaa gtgtactctt
    14221 taaaagatgt tgatttagca ggtatagaga tagtagaaga tggaaaaaca tttgagcata
    14281 atgcgttgat aaaagctaga gcaatagcaa aaaagactaa acttatagca atatcagatg
    14341 attctggctt agaagtagat gctttaggca aaaaacctgg tgtttattca gctagatatg
    14401 caggagaaca tgcaacagat gaagaaaata gaaaaaaact gttaaaagct atgcaaaatg
    14461 taccaatgag caaaagaaat gcaagattcg tctctgcaat agcagtagtt tttcctgatg
    14521 gaaaagaatt tgtagtaaga ggaatttgtg aaggaatgat aggatttgaa gaaaaaggta
    14581 aaaatggttt tggatatgat agcttattta tagtaaaagg atatgataag acttttggtg
    14641 aaatacctag tgttataaaa aattcaatca gtcatagagc aaacgcacta aaacttatga
    14701 aacaagagtt tataaaaagg gtagtgaagt aatgaaaata ggcatagtaa gcgacacaca
    14761 tatgatgatt aaaaatatgg aaaaaacaat accatatttg aaagaatgtg acctaataat
    14821 tcatgcagga gataacttta ctgattcaag atatattcat agcatgacta atgtaggtat
    14881 tattgcagtt aaaggtaatt gtgactttga tgctgttgag gaagaagttg tctttgaagt
    14941 ggcaaataaa accatattct tatgccatgg agataagtat ggtgtaaaat atggaactaa
    15001 tatgttagaa aaaaaggcaa ctgaagttga tgctgatata gttatatttg gccataccca
    15061 taccccattt agagaaatta aagatggtgt actttacata aatcctggaa gcacttcact
    15121 tccaagagga gtatcgtata aaagttttgt cattatggat atagaagaag atgacataaa
    15181 aattgaagaa atacgcatat aaaggtgtat ttatctaaaa aaatggcaaa aaacgctcaa
    15241 aaaattaaat tttatcaaat aagtacaacg atattaatgg aacacttgta aataaaaaaa
    15301 cttatgtgat ataattaagt ggttgaatta taaatagaat gaattataat accgttatcg
    15361 ggtattacat aaatatcact aggaggatta gaaggatgaa agcagaacta attaaaaaag
    15421 agggtaataa agttacttta aaaataacag tagataacaa taaatttgaa gcagcagtaa
    15481 ataaggctta taataaaagc agaaataaat acaatatacc tggatttaga aaaggtaaag
    15541 ctccaagaat tgttatagag actcaatatg gaaaaggtat attctacaat gatgctatag
    15601 aaatattatt cccagaagtt tatccagaag ctatcaagga attagacata gacccaatag
    15661 acaatccaga tttagatata gaagaaataa gtaaagataa tgggttggtt atggttctta
    15721 atgtagaagt taaaccagag tttgaattag gaaactacaa gggtatagaa atagctaagg
    15781 ttgagaatac tgtaagtgac gaaaatgttg atgctaaact acaagaaatg gttgaaaaaa
    15841 atgccagatt agtaagtgta gaagacaaag ctttagaaga tggagataca gctataatag
    15901 acttcgaagg ttttgaaaat ggtgtagctt ttgatggtgg taaaggtgaa aattataact
    15961 tagttatagg ttcaaacaca tttataccag gatttgaaga acaattagta ggtaaaaaag
    16021 ctggtgaaga agtagaagtt aatgttactt tcccagaaga atatcactca caagatttag
    16081 ctggaaaacc agttgtattt aatgtaaaaa taaatgatgt aaaagtaaaa gaattatctg
    16141 cacttgatga tgaatttgct aaagatacta gtgaatttga ttctttagat gaattaaaag
    16201 cagatgtaag agctaagtta gaagaagaag ctaaaaatag agcagatgca gaaactagaa
    16261 attcagtagt agaaaaagtt gctgaaaata cagaaataga aataccagaa gttatgatac
    16321 aacatcaaat agataatatg ttaaatgaac ttaactacca attacaatat caaggatttg
    16381 gattacaaca attactagag atgactggta gaactatgga agaattaaga gaagagagaa
    16441 aagaagatgc taaaaaatta gttaagtctt ctttagtatt agaagcaata actaaagctg
    16501 aaggaattga agcaacagaa gaagaattta aggctgagtt agaaaaaatg gcttctgctt
    16561 acaatatgga agtagaaaaa atagaagctt ctttaagaga tgctgacaaa gaagatataa
    16621 aaggtcaaat aaaaataaga aaaacaatag atttattagt tgataatgca acaatagctt
    16681 aataaaataa acgctaacta atatagttga cgttatgaaa tgtttagtat ataatgatgt
    16741 gcaaatataa tttagttaaa tgcgtataat aatttacagt agcttaaaaa agctactgta
    16801 aattatatag aataaagggg gtatgaaacc atggcattag tacctgtagt tgttgaacaa
    16861 acaggaagag gagaaagatc ttatgatatt ttttctagac tattaaaaga cagaataatc
    16921 ttcttaggag atcaagttaa cgatgccaca gcagggctta tagtagcaca gctattattt
    16981 ttagaagctg aagacccaga caaagatata catttatata taaattctcc aggaggaagt
    17041 ataacttctg gaatggctat atatgatact atgcaataca tcaaaccaga tgtaagtact
    17101 atatgtatag gtatggctgc ttctatggga gcattcttgt tggcagcagg agcaaaagga
    17161 aaaagactag cactaccaaa tagtgaaata atgatacatc aaccattagg tggagctcaa
    17221 ggtcaagcaa cagatataga aattcatgca aagagaattt taaaaataaa agaaacttta
    17281 aatgagatat tatctgaaag aactggtcag ccattagaaa aaattaaaat ggatactgaa
    17341 cgtgataact tcatgagtgc actagaagcc aaagaatatg gtttaataga tgaagtattt
    17401 acaaagagac cgtagataga gagaggtgtt aatatgtcta aatatgaaga aaaacgacaa
    17461 ttaaagtgtt cattctgcgg taaaaatcaa gatcaagtaa gaagattaat tgcaggtcca
    17521 aatgtatata tttgtgacga gtgtgttgaa ctttgtgacg aaattattca ggaagaaata
    17581 gaagatacta tagatgaaga tactacatct ttaccaaaac caaaggaaat gatggagatt
    17641 ctaaatgatt atgtaatagg tcaagaaaaa gctaaaaaag ctttatcagt tgcggtttat
    17701 aatcattata agagaatata cagtaaaaaa tctagtagta aggatataga aattcaaaag
    17761 agtaatatac ttttattagg acctacaggt tctggaaaga cattacttgc tcaaactcta
    17821 gcaagaactc taaatgtacc ttttgcaatg gcagatgcta catcattgac tgaagctgga
    17881 tatgttggag aagacgttga aaatatactt ttaaaactta ttcaagctgc tgattttgat
    17941 atagaaaaag ctgaaagagg tataatatat atagatgaga tagataagat tgcaagaaaa
    18001 tctgaaaacc catctataac tagagatgtt agtggtgaag gtgttcaaca agcacttcta
    18061 aaaatattag aaggtactgt tgcaaatgtt ccaccacaag gaggaagaaa acatccccat
    18121 caagaatttt taaagataga tactactaat gtattattta tattaggtgg agcttttgat
    18181 ggattagaga agataattca aaaacgtggt ggagataaaa cactaggttt tggagctaaa
    18241 atagaaagta aaaaagaatt agatttaggg aagctgtatg aaaaagtact tccagaggat
    18301 ttattaaaat atggtataat accagagttt ataggaagaa taccagtttt agctacttta
    18361 gagttgttgg atgaagatgc attaatgcag atattacagg aacctaaaaa tgctctagta
    18421 aaacagtata aaaagttatt ggagttagat gatgttgagc tagaatttga agaaggtgct
    18481 cttcgtgcaa tcgctaaaaa ggctatagaa agaaatacag gagctagagg acttagaagt
    18541 atagttgaaa gcgtaatgat ggaaactatg tttgaagtac catctagaga taatataaag
    18601 aaggttatag taacagagaa atctgtgaac gaagactcag taaatcctat catagtactt
    18661 aaggatcaag aggaaagtgc ataagatgat gaaaaggagc tttaaaagct ccttttttta
    18721 tgttaatatg ctaaatataa aataggtatc attatcataa aaatgtgagt aatataccta
    18781 gaataccaaa gacgaataca attgcaatgg aaccaatttt tcctttatat aaaagataaa
    18841 atgatgctat aaatgcaatt attccatata aatcccaatt aacttctttg gcagatgaaa
    18901 aagctgctga taatatgaat cctagagtaa ttggtctaag aactgtcaat aagttttcta
    18961 cctttttatt atttttaaat ttagaaaata actttgatat aatagttaga cctattaatg
    19021 caaaaattgt aacaccaata gttgcagcta gagaaccaaa gaagccagca gtcttaaatc
    19081 ctacaaatgt agcactattt attgctacag gacctggtgt agattgtgat atagcaagta
    19141 aatccaaaaa ctcttgatta gttataaagt gatatttaga tataaattct tgctggataa
    19201 atggtagcat ggcataaccg ccaccaaaac taaatgcccc tattttaagg aatattaaga
    19261 agagtagtat tatttctgac atagactata tacacctcct ccaattatta aataaatagg
    19321 gcttatattg aatacaccaa cagataaaac tgctataatt aatagtagta tgttagtttt
    19381 agactttggt agtttcttga acatgctcgt aaaagaatac aatataagag ctattacaac
    19441 aggcgcaact cctttaaaaa atccatctaa aattttagat gatgaatttt taaagtatag
    19501 atacgataag actaagacta tacaaaatga tggtaaagca gagcctaagg tacatataag
    19561 aactcctggt ataccataaa gtttatatcc taataataca gatatattaa ctgccagtac
    19621 tccaggataa ctttgagcta tggataaata atcaataaat tcttcctgct ctaaaagttt
    19681 ttgtttgttt acaagttcat cttgtataag aggaaccata gcgtatccac caccaaatgt
    19741 aaacgcacca atttttaaaa aggttaaaaa caatttcaac ataatagaaa cctccaaaag
    19801 ataaataaca tctaagtata ctaatattaa tattatatca taataaaaag ataatatagt
    19861 atgatagtat tctaagaatt tatcattaat gttgaaaatt aacttgttca aatatataat
    19921 attaaaagca aagcaattag actagaaaag gagtaatgtt gatggaacaa aattatacta
    19981 aaatagatca tgaattacca ttaattcctc taagaggatt agctatattt ccatatatga
    20041 tattaaattt tgatataggt agagagatat ctcttaaagc tttagaccaa gctatgatgg
    20101 atgaagaact tatattttta acttctcaga aagaagcaga ggtagatgag ccaggagaag
    20161 aggattttta tcatgtggga acaatctgta aagttaagca aatgataaaa ttaccaggag
    20221 atacagttcg tgttttggtt gaaggtgtat caaggggtag agtaaagaaa atagaacaag
    20281 aagatgggta tttcagagca gtaatagaag aaatagtatt taatagtgat aatttggata
    20341 gtgaaacaga agttgaaatt gaagcatttg taagaaatgt atttgatgcc tttgaagagt
    20401 atataaatat tggaaatagg gtatcaccag aaatattaat atctctagct gatatagaag
    20461 atgtagatag atttatagat acgatagctg caaacatata tctaaaatca agccaaaaac
    20521 aagaaatatt agaagaattt gatattagaa aaagacttga acttatttat tctatattat
    20581 tagaggaaat agatatatta aaaatagaaa agaaaataac tttaagagta aaaaaacaga
    20641 tgaataaggt tcaaaaagaa tattatctta gagaacaatt aaaagctata cagaaagaat
    20701 taggtgaaga agaagatata aattctgaag cagatgagta tagagaaaag cttaaaaaaa
    20761 taaaagcacc taagacaacc aaagaaaaaa tagaaaaaga gatagataaa ttttcaaaaa
    20821 tatcttctat gtctccagat gtatctgtaa gtagaaacta tttagatact atattctcat
    20881 tgccatggaa taaagagaca aaagataaat tagatataac taaggcaaaa gatatattag
    20941 atgaagacca ttatggatta gaaaaagtta aggagagaat actagagtat ctagctataa
    21001 gaactcttgc taagtcactt aaagggccta taatatgtct agttggtcct ccaggaacag
    21061 gaaagacatc tatagtaaaa tcaatcgcca gagcattaaa tagaaaattt gtaagaatat
    21121 ctttgggtgg agttagagat gaagcagaaa taagaggtca tagaagaact tatgtaggtt
    21181 caattccagg aagaataatt aatggggtaa aagaagccca aacaaaaaat cctgtattct
    21241 tatttgatga gatagataag atggcagcag attataaagg tgacccagct tcagcaatgt
    21301 tagaagtatt agacccagag caaaataagg actttgtgga ccattactta gaaatacctt
    21361 ttgatttatc aaaaatacta tttgttacaa cagcaaatag tctaggtaat ataccaagac
    21421 cattattaga tagaatggaa gtaatagaag tatctgggta tatagaagaa gaaaaattaa
    21481 atatagcaag aaaataccta cttccaaaac agattaaaga acatgcttta aaagaaaact
    21541 ttataaaaat agatgatgaa actttaagaa gtataattaa ccattataca agagaagctg
    21601 gtgtaagaac actagaaaga actattggta agatttgtag aaaggttgcc aaaaaatacg
    21661 ttgaagaccc aactcttgaa gaggttgtta taaataagtc tgacctagag acatatcttg
    21721 gaaaagacat gtttaagtat caacttgcag aagttaatcc tcaaatagga ttagtaaatg
    21781 gtcttgcatg gacagcagtt ggtggagtta cacttgaagt agaagtaaac gtacttaaag
    21841 gtaaaggaga aattgtatta actggaaaat taggagatgt tatgaaggaa tctgcgaaga
    21901 caggtatctc ttatataagg tcaatagtgg acaagtttga tatagaccct gaattttata
    21961 agacgaatga tattcatata cacattccag aaggcgctgt tccaaaagat ggaccatcag
    22021 ctggtataac tatggctctt gcagtaatct cagcacttac taaaagacct gttcctggaa
    22081 atatagcaat gacaggagag ataactttaa gaggtagagt cttagcagta ggaggggtta
    22141 aagaaaagtt attagcagct catagagctg gtataacaaa agtattaatt cctaaagaat
    22201 gtgaagctga tttagatgaa ataccagaaa atgtaaaaga aaaaatggag tttgtgcttg
    22261 tagaacatat ggatgaagta ttagaacaag ctttattaaa gagtggtgaa aataatgaaa
    22321 attagaagtt cagagataac tatgagtgct gtgaataaat cacagtatcc agcagaagga
    22381 atcccagaga tagcattggc tggtaggtca aatgttggaa aatcatcaat aataaataca
    22441 ttgcttaaca gaagaaactt cgctagaacc agtcaaacac caggaaaaac tagaactata
    22501 aatttttatc taataaataa tgaattttat tttgtagacc ttccaggcta tggatatgca
    22561 aagatagcta agtctgaaaa agaaaagtgg ggaggtataa tggaaagata tctagaaagt
    22621 agacaagagt tatgttctat attcctactt gtagatatta gacatgagcc tacagcagat
    22681 gataagctta tgtatgaatg gataaagcac tttggatata actgtgtagt tattgcaact
    22741 aaggcagata aaatatctag aggacaatat caaaaacaca taagtataat aagaaaaaaa
    22801 ttgcaaatgg aaagtagtga aaaagtaatt cctgtttctt cactaaaaaa gactggtgtt
    22861 gaagaattat gggaagagat tgtaaatcaa tacaatcaac atggatatga aataacagta
    22921 gattaaattt aaaatgttaa atattgacat aagatttatt tgaataataa atgtaataat
    22981 agttagtttt aattatatta atattaaagc aaaatatagg atgccttaaa atagttttaa
    23041 tgaacttttt ttggcatcct tattgtttat aaacaataaa tatcagtaat tttgctaaat
    23101 actaataaat tttagtaagg tatgggaaaa ttagtataaa ttagttcaac taaaaaatta
    23161 ttgacttatg tagtcagcaa taaatagcat ttaagaaata gatttatctg tttttctcat
    23221 aaagaaaaca gttagtataa gccctataaa acatactgat gctgcaatcc aataagactg
    23281 attgctagct ataacatagg ctgatgtgtg acttttaaac ttttgattgt atgtaagact
    23341 ttgtgcaaaa aaactactaa aaaatgctgt tccaagagca aatgataaat tacgaatagt
    23401 tgcaagaaaa ctgcctccgt acccctgttt ttgaggagga acatctgcta aaatactact
    23461 attgtttggt gaactaaatg ctcctagccc aagtccaaaa ataactaaac atacaattaa
    23521 aagatacaat ggagaatctg cttttaaaag tgccattcca actagtgaga tggtcataaa
    23581 tgaaaaagat gctgttagaa tgttttttgc accgtgttta tcagaaagtg aacctgcaat
    23641 aggtgctata agtaccataa taagtggatg tacagtcatt acataaccag ccatcatagg
    23701 agataaattt tttaattgtt ctaaataaaa tggaagtaga aaagatactg ccatttgagg
    23761 aaaataacaa gctactccaa tgatattgcc tacagtaaag tttctatttt taaatagagg
    23821 taggtcaata aagctttgtt caaattttac ttctcttaat gccaacaata agaagattat
    23881 aagtgctgtt atacctaaat acaatcttgt attacccttc tcattcattg caagtaatat
    23941 aagcgtagtg caagatgcga aaagtagaag acctgaaata tcaaagctct tgttttgttc
    24001 atccaaaaca ggtttaggca gaaatttaat gccaagaaag actgctataa taccaatagg
    24061 tatattgata ataaaaatag aaggccatcc aaaatgttct aaaattatac ctccaattac
    24121 aggaccactc atatttccta taccaactac agctccagtg attcctatag cttttccttt
    24181 ttcatttgct ggaaatgcat tggaaactat accaagccca gtagccatta aaatacttgc
    24241 tccaactgcc tgaaagattc ttgaagaaat taatgttgat aaattgtttg acatactaca
    24301 cagaaaagaa cctattgtaa atataaaaaa tcctaatgcg tatagacgat ttgaacctac
    24361 tttatcacca agttttccga aaaataacat agtagctgtt acaacaagca tataagctgt
    24421 tacaacccac tgaatttgtg acatgttaat tttaaagtca gcagcaattg taggatttgc
    24481 gatatttagt atacttccat caagagtaga cataaataca ccaatacaga tgataatcaa
    24541 tactatccat ttttgtttca tgataacact ccaatcttaa tagattttat aagtacgata
    24601 taattgtaaa ataaacaaca aaaaaagcac ctgtatatta ggtaccttga atgtgtctaa
    24661 tttcatgaat aaatacggta gttgaaggat ttgtatagat tactcatgta aaattacata
    24721 aaggtactca tatactattt tcttctacca tccagatttt actgtcggct ttggaatatg
    24781 accaaattat gccataaggc tcgcgggctt ttaccgccga tagggaattt cacccgttta
    24841 tgaagaaaaa cagatgtatt ttgtaatatt attttaacat aaaattataa tggaaacaat
    24901 tggatttaag taatatccag ctgtattaca atacaaatat ttcaatatgg acacttaaat
    24961 tgtatttata gatagaataa ggtacagtat gagaatctat aataattaga taaaattaat
    25021 atgttattag tattagatgg taagttttaa atttgtcaaa atcagaaagc tgtaataaaa
    25081 ttcttataat atgaatatct taattaagag atattgtaaa ttatgaggag gcgctaatat
    25141 ggaaggaaag gtaaagaagg cattcccagg tggaaataca tcacaaggct catattcttt
    25201 ttttgactat ataattcctg aaaatgtaaa aagagttttt tgtttaaagg gtggacctgg
    25261 agtaggaaaa tcctcactta tgaaaaaaat ttataaagag tttttgcata gaggatatga
    25321 tattgattta tatcattgtc cttctgaccc aagttcgttg gatggtttag ttataaagaa
    25381 attaggcgtg gtacttatgg atgcaactgc cccacatact atggacccaa agctacctgg
    25441 agctttggat gagataatta atttaggtga ttactggaat acagaagaat tagaaaagaa
    25501 taaacaagaa atatcagttt atgataaaga tattagtaat tcatttaaaa gagcatttaa
    25561 gtttttaaag tcagcagaac caatttttag agacatagaa gaaaaatatt ctgattgtat
    25621 ggattatggc aaagtaaatt tggtcacaga agaatttata aaaaggttat ttgatggagt
    25681 taaaagcaca ggaaatctaa aaagagaaaa gcatttattt ggttcagcta taactcctgt
    25741 agggtgttta gattatacag aaaacatttt aaaagatgta aagaaagtct attatttaga
    25801 tggagaaata ggaactggga aaactacatt attaaacaaa gtatataaga aagctactga
    25861 aaaaggttta aatgtagaag tttatcatta tccacttatt ccagagaaaa ttgaaactgt
    25921 actattaact gatttagata taggcataac tataagtacg acttttaaag aagaagatac
    25981 aattgattta aatcagtttt taaatagaga aaaactactt aaatatgaag aagatattaa
    26041 atttgatgaa aaagttttag atgatttaat ttgttgggca gtactaaatc ttaagagagc
    26101 caagtctaaa catgatatta tagaaagtta ctatagtcct aatatgagat ttgatgaagt
    26161 agggaaatta agagataagt taattaaaag aattttaaaa tatgaggaaa acttataaac
    26221 gtatatgttt aaaattaatg ttaataataa tataattttt agtaaattgg tgtagctttg
    26281 aggctatgcc attttacttt tttttgctaa aaaatgatat taataatctc caaagccatt
    26341 atttgttttt cataattatt atttcctttc ctaatttatg tttttttata atatcacaac
    26401 aatgtttatt gaaagtttat ataattttaa gaacatctaa aaatgcatac ttgatattgg
    26461 taaattagtg ataggagttc aatgtatgat attatatact aaagatgaat tttaatatat
    26521 aactttgata taataagcat atgtaaatgt ttaatattta attaaagaaa attatcatat
    26581 aaaaataaat ttgtaaggag caatacagta tgaaaaaaca atatgtgttt ataatactag
    26641 caagtactat tttaggtata cttgttggaa ccatatttag agattatagc aatgaagaaa
    26701 cagtttatac aagcaaagac aagtcaataa gaaaagaaat aaaaatgaca agaaaatcta
    26761 taaaagaatt aaccaaagag aaagacaagt tagataaaga aattaattca atgaaacaaa
    26821 atcaaaaaaa ttctgaagaa atatcagaaa tagaaacact tagagatagt ctatcatatt
    26881 cagatgtaaa gggtagtggg ataatattaa gtatagatgc tatagatgaa aaaacaggga
    26941 atatagctaa tagtatagac tataataaga ttcttgtaaa agttataaat gaattaaaag
    27001 taaacggagg aaaatacata gaaataaatg gtcaaagaat taatcaatat tcagaagttg
    27061 tacttgcagg aagccatata aatataaatg gagttcctgt agcacaacca tatgaaataa
    27121 agtgcattgg agataaggag aaattatcta attatgtaga taaaggtagt aaatatttag
    27181 atagcataca aaccaattat ccaatgaaaa taagcataaa aactgaagaa aatatctcta
    27241 tgaaaaaaat gaatatacct aataaattaa agtatataaa gggtgattaa tattatatta
    27301 gaggaaagca gtttgccaat gttaatacca gaaaaacttg caaagaaata taatgtattt
    27361 ccagttgagt ttcaagatga taatttagtt gtagaaatag aagatgagga tatttatgct
    27421 ctacaggact tgagattagc tacaggtaaa gaaattatat tgaagaagga gaaaaaagaa
    27481 cttataagtg aaaagattga aaaatattat aatagctttg aacttgatga ggattatgca
    27541 aaaaaattat ttgaaaatct tttagaaaaa gctataaaag aaaatgcaag tgatatacat
    27601 atagaaccat ttaaagaaca tttaatagtg agaatgaggg tagatggaga actaaaggaa
    27661 gtatcaaagt ttttagttga tgtctatcca tcattgtcta cggttataaa attaaaggca
    27721 tcaatggata taacagaaaa aaggcttcct caggatggta gggtggatat aaagttaggt
    27781 ggaaatttaa ttgacattag agtttcatca ataccaactg tctatggtga aaaaatagtt
    27841 ttgaggatac ttaatagaga tactttttta aaagacaaat tagaacttgg tttttcagag
    27901 gaagctataa aatctataaa tcgtataata aataaaagag caggagtatt attagtgaca
    27961 ggtcctacag gtagtggaaa gactacaaca gtatattcct tattaaatga tttaaaagga
    28021 ataaataaaa atattatgac tatagaaaat cctgtagagt ataagatgga tggcataagt
    28081 cagattcaag taaattcaaa agtagggttg agctttgatg taggtcttag agcgatatta
    28141 agacaagacc cagatataat aatggtcgga gaaataagag atgcagaaac agctaagata
    28201 gcagtaagag cagctataac aggtcattta gttataagta ctttacatac taatgatgca
    28261 gtatcttcca tagctagatt actagaaatg caaataccac catatctttt aaatgcctct
    28321 cttataggtg ttatatctca aaagttggtt agaaaagttt gtaatcattg tagccatgag
    28381 attatgataa aagataattt tagtggagat gtaaatacta aggtagctgt agggtgtgaa
    28441 aaatgtaatg ataaaggata ctttggaaga acagcaattt atgaaatctt agaaattaat
    28501 gatgatataa agacatgtat aagaaatatg gaggattcta gtactattaa agatgtggca
    28561 caaaataatg gaatgataac atttgaagat agctgtaaaa gactaataaa tgaaaaaata
    28621 acgacattag aagagtgttt agtagtaaat gaaatgattt aactgaattg tatagttaaa
    28681 cttcgtttgg tcagttgtct ttatttaatc tattttaatt aagatgtttg agtataaatt
    28741 atatttaagt gaaataaaat taaatgcatt aaattagaaa atattaagtt tatttaattg
    28801 taattaatat aatttggaag gtattatagt acatgagatt atctaaaaat atattttata
    28861 atttagaaaa gttttattta gtattaaata gaatcagtga taaagaaatt agagtaattt
    28921 gcaaagagat aggcatattg ctggaatctg gatgtgaaat tacaaaaata tttgaaatca
    28981 ttgagagtca gtcaagtaaa aaagtaaaga atttgcttag tatagtatca aatcatattc
    29041 aaaaaggtaa ctcaatagca gaatcatttc aaataacagg tatattttct aaattcttta
    29101 taagtatgat aaaagcagga gaaactagtg gaaacttaga tataataatg agtgatttat
    29161 ctaattatta tgataaagaa tacaaattaa aaatgaaaat aataactatt tcaatatatc
    29221 caataatact tataatatta tctatcttat caatgttgtt tatattcgta tttgtaatac
    29281 ctaattttca ggtggttttt accaacaatg gaattgaacc acctttaata actagagttt
    29341 taatgggaat atctacagtg gttacaaata acttagctta tataatattt agttttatat
    29401 tgttttcaat aggaagcatt tatttcttta taacaaatga taatataaaa aaattgatta
    29461 attcgttaaa attcaaaata ccttttataa aaaaaattaa tcagttagta gctacaacaa
    29521 gattttcaag ggcattgtcc gttttaatta gcagtggaat acaaattgtg gaagctatag
    29581 acatgtcagc tagtgttata gacaacgaat ttatttatga aaggttaaag atttctaata
    29641 attatataaa aaaaggaaat agcataggta aatctttgaa tttagcaaat gtttttccaa
    29701 aattatttat ttcaatggca aatacaggag aagaaagtgg gaaactagat aaaagtctaa
    29761 atgtaataaa taaattttat gaaaatgaat taaataacaa aatagagcaa ataatgaaat
    29821 ttatagaacc tatgctaatt gtatttatgg gattaattat tggcactttt attttagcaa
    29881 tggttgttcc tatgtttgat gcaattacta atttttagag agaaaaataa attttattag
    29941 atgaaacttt tgaaaaggag agaatattta attgataaat ttgataaata aaaaacgaaa
    30001 aggatttaca cttgttgaaa tgattgtagt agtaactatt ttaggcgtta tatctagtat
    30061 agcattagtt aagtatagta aggttcaaga aagtgccaaa ttaaatgcag actatacgaa
    30121 tgctgctaat atagtaactg cagctagcat ggcaattaat gatgatgaaa agacaataga
    30181 ctctctaagt gtagaaacat tgaaggaaaa gggataccta aatactgttc cagttcctca
    30241 gagtacatca ggtaaattcg aacttgtcat aaatgatagc ggaacagata taagcgtaaa
    30301 tataaattct aaacaatttt atccaaaata atattttata ttgattgctg taagttttaa
    30361 aattattttt atttaagaag gagatggcta taattaaaaa aattctaaac ttagaaataa
    30421 atgatgatta tataaggctt gtatttttaa gaaaaagtca taaaaaagtt tttatagata
    30481 aatcaattat aaaagagatt aactttgata taaaaaatga tagtaattcg attgagaaga
    30541 ttaaatatat agaagatgta gttagatttg taaaagagga gattggtaaa tcaaaaatat
    30601 tatataaaaa tttatacttt aacattcaaa ttcaagatat agtcattaga aatgttgaag
    30661 ttctaaatac taagaaaaaa agagacatat taagcatgat tgaatttgaa ataacacaat
    30721 acattccaat aaacataaat aactattcaa taaaatataa agttataaat tctaaaaatg
    30781 ataaattgaa tatacaagta attcttttcc caaagagtat tattcaatta attaagaaca
    30841 tttcagaaaa tctaaatatg aatccaaaga ctataaatat aaattttgat atattacaaa
    30901 agcttataaa cttaaattta atagagaatt tttcagaaga aggggtattt atagaatgta
    30961 aaaaaagtca gttaattata aatataacaa aagataaaaa aataagagaa acatacttgc
    31021 tatcaaaaga gggaaaatca tatgagttca taaaaagatt attaagggat tttaagtatg
    31081 tttattacta tggtatagaa aattgtttta ttgaagaata ctttaaatat acagataaat
    31141 ctattgaagt aaatccatta agattaaaag ataaagtaaa agtagaaaat aattttgatg
    31201 cagatttaga agacaatagg ataaattata taaatagtat aggaatgatt atttaagtga
    31261 aagtggataa aacaataaat tttcttaatg gatttaaaaa aactaaacca tgtaataaaa
    31321 tctataaaat aataatagtc ttaattttaa cgtgtatttt atttaaatca tttatgtatg
    31381 tgaaatctat aaatgaactt gaagattata taaatcaaaa taagctagtg gataaatcaa
    31441 agcacacttt accaacaaca gataaaacta gagagaaatt ttctaaaata aaacttaatg
    31501 aaataaaaaa aatatatgaa acaattggaa taaatagtat tactaaaata tcgatagata
    31561 aaaataagct agagatggaa ggtgtgtgta gtgatttaga tgttttaaac aacctaagga
    31621 aaataaagta cataaaatat tattacatag acagtattgt aagagatgga gaatattata
    31681 gatttagaat aaaaagttag ataggtgatt atttttgaga ttaaataata gagaaaaaaa
    31741 tctacttaaa atattgttaa tattagttat tatattggca agtgatatag cagtaagtta
    31801 tttggaagaa aacctaacta gtttgaagaa tgaaaagcaa aatataataa ataaaataaa
    31861 taatcaagat aattatcaaa taaaggataa taagcatata gatgataaat atatagaaag
    31921 tgttgaatta aataaaaatg aagaattgaa aaataatttt aataactcat ttttagataa
    31981 aaaaacaaat aaagatatag tgttattagt agaaaatgaa ctgagagata ttgtgaatgt
    32041 agaatatatt aatcaagaaa gtagtttaga taatcacaat aaaaaacaag ttaatttaga
    32101 aataaaagtt aatggagaac ttgcaaatgt gttgaaactt gaaggtgtaa tgaagaagtt
    32161 aagactaaat aataaacttg aaaagataga aattaacaaa ttaaaagtca ataattttga
    32221 tgttcaaaat attccaaatg aatataaaca agaaaaagac aatattgttg aatgtaaaat
    32281 gacagttaga gtcatataac aaaaaagaat agataaagta aaaaactatt atcaattaat
    32341 aaaattttat agaggaatta gttttacgat aattcatttc tacaagaggg attgttgatg
    32401 attttatcga aatcctaatt aaagttaata tattgtacca aaatataagt gaatttaata
    32461 gaatatttac ttatactata gattgattaa taaaaaaatg gtataataac aaattgtact
    32521 ttaatttaat aataagggag tggaagtcat attgttaggg agaaatgagc tatgcccttg
    32581 tggaagtggc aaaaaataca agaaatgttg tttaaataaa gatattgttt cagaaagagc
    32641 atgcagaaaa actgaacttt cacaaaaaca atatacagat ttatattcaa agttatatga
    32701 ttattcaaga caggataagt ttaaagaaga atgtgaaaaa gctaaagaaa tgttttatat
    32761 aatgcaaaat gatagtgtaa atgaaaaatt tgaaagattt tttaatactt atttaataca
    32821 agaccacata atggaaaata aaaaggttat gacagttggt tttcttgaag aaaatggtgc
    32881 aaacctaagt caatcagaag tatcaatatt aaaaagtatg tttgaatcat acgtaagtat
    32941 ttatgaggta aaagaagttt ctgctggaaa aatagtatta aaggactgtt taagtggaaa
    33001 tgaactttgt acagaagatg taaaacttct gagaagtttt aaaatcggaa gttgtatgat
    33061 agctagaata gttgatattg aaggaactaa catattgata gatataacta taagtatatc
    33121 aaatgaggtt aaagatataa ttttaaagga tattatgaat ctattcaatc aatatcaaga
    33181 tgtatacaaa gatatgaagt cgttcttaat ttatcataca catatactat acaagtatat
    33241 acaacagctt ttagacccaa gtatagctga atatttaaag agagaaagag ataaaaacga
    33301 tacaaaagtt aattcagaaa atgaattagc tgaagaagaa tgtaaagttt tagatactct
    33361 taaagaaaat gtagaaaaag aaaatataga tgcatgtata gagttttgga atgaatataa
    33421 gaaaaatcat gaaaatataa aaggagctga aaatggttgg gcagctgctg ttgaatacta
    33481 tgttaaaaaa gaagcaggac aacctataac tcaagttcaa atatcaaaga aatacgatat
    33541 aagctctagt acactaggaa agagatacaa agatttaaaa atatcttaat taattataaa
    33601 aagctttaag tcatagataa agaatctata gtataatata tgtataatgt ttagaaagag
    33661 gtattaataa tgagtcttag tttaggaaat gcaattgctg tatcaacgaa ctttataaaa
    33721 tctaacccag ctgtacctgt gtacaacgga gaagaaatat atgcagttat ttatcatata
    33781 gaaataggat ataataatgg tgtatcacct gataccaaac aatatataat aatagactat
    33841 aaagagtttg atttatctat ggataaaaaa aatgaactaa taaatgttgc taaagagtac
    33901 tgtaaatcta aaggtattgt agaaaacgaa aaccttgaaa taaacctttt agacaatgaa
    33961 gaagcagaga acttcttaga aaaggtgttt aataacatga aggttataag aggtcttata
    34021 actaaaaaag gataaataaa tggactatat aggaatagaa aatataacac cttatgaaaa
    34081 tacatatgaa tttagtgtat atgaatatga tgatgaaatc accttaggta gtgaaaagtt
    34141 atatgtgtgt gaattaaggg ttgtattgat taaagttaat tctctgtatg ttgaaagatt
    34201 gcataaatca gttgaagcaa tggtcttagt aaaaaacttg aaaaaggatt tagataaaac
    34261 acttgttgta aacaaaataa agaattttgt gctagatgag atttgggtag aaaatctagt
    34321 aaaagagaat atagaagtta tatttgtaga aagctaggaa taaccctagc ttttttatat
    34381 tacaatctaa gagaggaaaa caatatgtta agagtatcta atgtaaaact tggaattgat
    34441 aaagatatat ctttattaaa agatgttgta cttaagaagc taaaaataaa agaaaaaaac
    34501 ttagtcaaat atagtatata taaagaatct atagatgcta gaaaaaaagg aaaaatggaa
    34561 tttgtttatt ctgtagatgt agaagtcaaa gatgaaaata aaatacttaa ctcaaaaata
    34621 aaagatgtaa caaaaataaa ggaaatcaga tacataaatg tacctgtggg tgataaaaaa
    34681 ttaaagaata atcctttggt aattggtagt ggaccagctg gtttatttgc aggtctgctt
    34741 ttagctcaaa tgggttatga accaatcata cttgaaagag gtcttgatgt agacagtaga
    34801 accaaagata taagtgattt ttggacaact agaaaattaa aaaataattc aaacgttcaa
    34861 tttggagaag gtggagcagg aactttttcg gatggtaaac ttacaactag aataaaagat
    34921 atacgatgta gaaaagtatt agaagagtta gttcagtttg gagcaccaga tgaaatatta
    34981 tactcacata agccacatgt tggaacagat atattaaaaa atgtagttaa aaatataaga
    35041 aatgaaataa taagtttagg tggtcaagtt agatttaatt caaaagtaac agatatagtt
    35101 gtatcaaatg attctataca atctgtaata ataaatgata ctgaaaaaat agatacagat
    35161 acaattatac tagctgttgg acatagtgca agagatactt atgaaatgtt gtattcaaga
    35221 ggtataaaaa tagttcaaaa accttttgca ataggagcta gagttgaaca tccacaagat
    35281 ttaataaata aagcacagta caaggatttt tataatcatc ctaggttagg agctgcagat
    35341 tatagactta tagagcatgt ttcaaatgga agaacagcat atactttttg tatgtgtcca
    35401 ggaggtagtg tcatagcatc tgcatcaaat gattttgaaa tagttacaaa tggtatgagt
    35461 gaacatgcaa gagataaaat aaatgcaaat agtgcatttt tagtaaatgt aacgccagaa
    35521 gattttaaga gtgataatcc actagcaggt gttcatttcc agcagaagta tgaaaaatta
    35581 gcttttgaat taggtggaaa aaattacaat gcaccagttc agcttgttgg agattttata
    35641 aacaataaga cttctttgaa tttaggaagt gttgagccat catatagacc aggatataca
    35701 cttacaaatt taagtgaatg tttgcctagc ttcgtaacag agactatgag agaagcgttt
    35761 atatctcttg ataaaaaatt gaatgggttt gcaatgtatg atgctgtttt gacgggagta
    35821 gaaactaggt catcatcacc aataagaata gtaagagatg aaaatacttt agaatcagtg
    35881 agtattaaga atctatatcc atgtggtgaa ggcgctggat atgcaggtgg tatagttaca
    35941 gcagcagttg atggtataaa atgtgcagaa aaaataatac aaaaatacac caataataca
    36001 aaaatttaac ataaacttaa tgatttttta atatttaaca tgaatttaac attatcactc
    36061 ctataatttg ataaaataca ataggttata aaatttttag atacagtaat ctctttacaa
    36121 ggaggaaata atttgaacat tataataagt ctaatgggtg gattaggtct gttcttatat
    36181 ggtatgaacc ttatgggaga aggtcttcaa aaatctgctg ggacaaagct aaaaaagata
    36241 ataaaactac ttactagtaa cctatttatg ggagttttgg taggtacagg agttacagca
    36301 gtaatacaaa gttcaagtgc tactactgta atggttgttg gtttcgtaaa tgcaggaata
    36361 atgactttaa aacaggcaat aggagttata atgggtgcta atatagggac tactgttaca
    36421 gcccaattgg tatctttcga cttaactggt atggccccag tagcattagg tgtaggtatt
    36481 atactttatt tatttggaaa taagcctaga ataaaaaata tagccgaaat acttataggt
    36541 tttggtatat tatttacagg tatggatttt atgaagatgg cagtggagcc actaagagac
    36601 tatcaaggat ttactgacct acttgttaca tttggtagat atccactact tggattatta
    36661 ttgggatttg ggattacagc aataatacaa agttcaagtg catctatggg tatgttggtt
    36721 gcactggcag cagaaggtct agtgccatta tcagcagcac tgccaattct ttatggccaa
    36781 aatattggta catgtgtaac ttcactgtta tcaagtattg gtgctaacaa aaatgcacga
    36841 agagcagcta tgatgcatct aatcttcaat gttttaggaa cggtgatatt cttaatattc
    36901 ttgaataaac cagtagtaag catggttaca agttgggatc caagcaatgt tgcaagacaa
    36961 atagccaata cacatacatt gtttaatata atatctgtat tgatactttt accatttaca
    37021 aatcttatta taaaactagc tataaagctt gttcctgata gagcaggtga tatagatgaa
    37081 gatgaaacta aaactattaa atatatagat gatagaatga tagaaactcc ttctatagct
    37141 cttgcaaata cgataaaaga agcacttcgt atgggtgaga aggcgaagga aagcctaaat
    37201 gcatctatgg aagccttagt agaacattca actgaaaaaa tagctaagac atatagacga
    37261 gagagattaa tcaatgattt acagaaagct attttaaatt acttacttaa actttcaaaa
    37321 gcacctttag atgatgattc aagagaagtt gtggatactt tgtttaatac agtcaatgat
    37381 atagaaagaa ttggtgacca cgctaaaaat atagctgaat tatcgcaagt tgcaatagat
    37441 tcaaatattt ctttctcaga agaaggacaa tctgaacttg atgttatgta taatagagtt
    37501 gtttcagcat atacttatgc attagaatca atgagaactg ataatgttga tttagcttgt
    37561 aaggttataa aaattgaaga acaagttgat ataatggaga aatcttgtag agctaatcac
    37621 atgtatagat tgaacaataa tctatgtagt atagaaaatg gagttattta tttagacgta
    37681 ataagtaatt tagagagaat atctgaccat gctgtcaata tagcacaaca agttatagcg
    37741 aagagattag gaaatgatta aaaataatta atttaaaata atataaaatt taaaatagag
    37801 gataaataaa agagaaactt taaatgatac gtttagagtt tctttttttg taaatttatt
    37861 tgactaaaat ttttaaattt atacatagtt atagtattta gaagaatcga tttcctgata
    37921 ataaatgatg agatatgtat gattttgtgg caaactttta aaaaaaacac ctatattttg
    37981 tgttataatc tctttaaaac gaatatgctg aaaagaggga tttaaatggg aaaaataaat
    38041 tttgattata gtaaagctac agagtttttt tgtcaaaacg aaatagatgt catgcaacca
    38101 tatgtagatg ttgcgcacga catgttacat aataaaactg gtttaggaaa tactttttta
    38161 ggatggatag accttcctaa aaattatgat aaagaagagt ttgacagaat aaaaaaatct
    38221 gctgagaaga taaaatcaga ctcagatgtt cttctggtaa taggtatagg aggctcttat
    38281 ttaggttcga gagctgctat agatatggta agtcattctt ttaggaatgg acttaaaaaa
    38341 gagcaaagaa aggctccaga agtatatttt gtagggcata atataagctc aacatatatt
    38401 atggatttat tagatataat tgaaggaaag gatatttctg taaatgtaat atctaaatca
    38461 ggaactacta cagaaccagc tctggctttt agaatattta aagattactt agagaaaaag
    38521 tatggtaagg aagaagcaag aaagagaatt tatgcaacaa cagatgcaag taaaggtgca
    38581 cttagacagt tagctacaga agaaggatat gagacttttg taataccaga tgatgtaggt
    38641 ggtcgttttt ctgtattgac agcagttggg ttacttccta ttgctgctgc tggacttgat
    38701 attgatgcta tgatgaaagg cgcaaatgat gctagagaag catttcaaaa tcctgactta
    38761 aaaagtaatg atagttatag atatgctgtt gctagaacaa ttttacatag aaaaggaaaa
    38821 gatgtagagt tattagtgaa ctatgaacct caactacatt atgtaagtga gtggtggaaa
    38881 cagctttatg gagaaagtga aggaaaagaa aataaaggtt tattccctgc ttctgtagat
    38941 ttctcaacag atttacattc tatgggtcaa tacatacaag atggaaaaag gcttttattt
    39001 gagacagtac ttaatgttga aaactgtaag agaaatataa ctataagttc agaggaagta
    39061 gacttagatg gtttaaatta tttagcaggt aagactgtag attttgtaaa tcataaagct
    39121 tttgaaggaa ctctattggc tcatacagat ggaaaagtac ctaatttagt aataaatata
    39181 cctcaactag atgagtataa ttttggatat ttagtttatt tctttgagaa ggcttgtgga
    39241 ataagtggat atttattggg agttaatcca tttgaccaac caggagtaga agcttacaag
    39301 aaaaatatgt ttgctttact aggcaaacca ggttatgaaa aagaaaagga agagctagaa
    39361 aaaagactta aataatttta aatagttaag gtttaattaa gattaaaata atataatgaa
    39421 atcatcgaaa aggagtttac tcaaaataga tgatttcatt ttttttatga aaaattggga
    39481 aaaatatatt ttgataattt atattatatt aagataggga gtggtatgag atgtcaagaa
    39541 gaaagaaagg gataagttta gtaatattag ttgctataat aagttcaata cttagtagtt
    39601 ttctaacaat aattttagtt aaggacaatt tagtaagcaa atctacagga agttctacgc
    39661 cgatagttgt aaatgatgat ggtaagagtc aaaatattta tcaagcagtt gcagaaaaag
    39721 ctacgccatc tgttgtaggt attacaacaa ctagtgttga tactagtaat atgtttgcaa
    39781 taccaactga aacacaaggt gtaggaactg gaatcatagt tgattcaaat ggatatatac
    39841 ttactaattc tcatgttata tcagatggtc aagctacaag tgtaaatgta ttattcaatg
    39901 atggttcaac aacttcaggt aaagtagtat ggtttgacca acaacttgat ttagctatag
    39961 ttaaggttga taaaactgga ctaacaccag cagaatttgc tgatagtgac aaagtaaaag
    40021 ttggagatat atcaatagca ataggtaatc ctcttggatt agattttcaa aaaacagtta
    40081 ctcaagggat aataagtgga ttagatagaa ctatacaaac agaaaaaact aatatgactg
    40141 gtttattaca aactgatgca agtataaatg caggaaatag tggaggacca ttgttaaatc
    40201 aaaaaggtca agtaattggt ataaacacag caaaagcttc tcaagcagaa ggattaggat
    40261 ttgcaatacc aatcaataca gctaagagta tagttgaaga agtaatcaaa aatggaaaat
    40321 atgaaaaagt aactttaggc ataaaaggta cagatgtatc aaattatgaa gcagcaacag
    40381 gtacaaaatt aagtactgat aaaggtgttt atgttgcaga agtaatatct ggttcatcag
    40441 cagaaaaagc tggagtaaag gtaggggata ttataactaa agtaggagat acagatataa
    40501 caggtatgaa tgatttaaat aaaaagttgt atactttctc aaaaggtgct agtacaaaaa
    40561 taacagtaaa tagaggcgga aaagcagtaa caataaatgt gaatttctaa atatgaccag
    40621 aaagaaggag actacatggt aaagtgtagt ctctattttt atttaatttt tatagtatat
    40681 acatctaaat taattaaaat gatgtattgt ttatagttta ttgctatatt ttcttataaa
    40741 aataaattta ataaatattt aaatttaatt tacaaaaaca atataaatat cataataaaa
    40801 taaaattttt taatattact aaaaatatat agacaaaata ataacaaata tagtattatg
    40861 taattgtaga aatgcttttc ataggtatat tctatgaaga tgaattgcat aaaaatgaaa
    40921 aaatggaatg gatattattt aggggtgaaa aatcatgaat ccattagtta taaacttaca
    40981 aaaatgtagc atacatgatg gaccagggat aagaagtaca gtatttttta aagggtgtcc
    41041 acttgaatgt gtttggtgtc ataatccaga gagtcaaaca tatacaaaac aagttttgta
    41101 taatgaagaa agatgttcaa aatgtgaagc atgtataaat atatgccctc ataaggcaat
    41161 ttacaaaggt gaaacaaaaa tatgcttaga ccaagataag tgtgagtttt gtgaaacttg
    41221 cttagactat tgtgtaaaca atgcaagaga gattgttggt caagagtatt ctgtaagaga
    41281 cttggttaaa gagatagaga aggatagaat tttctatgaa gaatcgggtg gtggagtaac
    41341 actatcaggt ggagaagtaa tggctcaaga tatggacttc atttgtggag taataaacat
    41401 gtgcaaatca aagggaatcc atgtagcaat tgatacatgt ggctatgcaa agtcagaaaa
    41461 ttatgaaaga gttgctaaat gtgcagattt gtttttatat gatattaagc ttattgatga
    41521 ggataagcac ataaaattta caggaaaatc aaatgactta atactgaaaa atgttaagat
    41581 tttaagtgaa ttaggggtta acataaatat aagaatacca ttaattgtag gagtaaatgt
    41641 agatgatgaa aatttagagg ttaaaaaaat gatagagttt ttaaagcctt tgaatataca
    41701 agcagtaagt cttcttccat atcataatat tggtaaacac aagtatgata aaatttataa
    41761 aaagtatgaa ggagaagaac tacaaagacc atcagaagaa aaattagagg aaataaaaag
    41821 actgtttgaa gcaagtaatt tcaatactaa gattggaggg taataaaatg gcaagaggaa
    41881 cttttgagag aactaaaaaa ttaagagaag aaagtattaa tgcagaacca cacatatcta
    41941 ttgaaagagc agtacttatg acagaagctt ataaaaaata tgagggaagt gtagagattc
    42001 ctgtacttcg tgctttatca tttaagcatt atattgagaa tagaactctt agcataaatg
    42061 atggagaatt aatagtaggt gaaaaaggtg attctcctaa tggagcacca acatatccag
    42121 aaatttgttg tcacacaatg gaagatttag aagtaatgca caatagagat ataataaatt
    42181 ttagcgtatc agaagaagct agaaaaatac ataaagaaga aataattcct ttttggaaaa
    42241 aaagacaaac aagagataag ataataaatg caatgacacc tgagtggtta gcagcatatg
    42301 aagcaggtat gtttacagag tttatggaac aaagagcccc aggacataca gtttgtggag
    42361 atacaatata taaaaaagga tttttagatt taaagaaaga catagaagca agattaaaag
    42421 agctagattt tcttaatgat ttagatgcat ataataaaaa agcagattta gaagctatgg
    42481 caatagcttg tgatgcaatg gttatattag gtaaaagata tgctgagaaa gcaagacaaa
    42541 tggcagaaga agaaacagat gaagctaaga aaaaagattt attactaatt gctgaaactt
    42601 gtgatgttgt accagctcac aaaccagaaa cttatcatca agctatacaa atgtattggt
    42661 ttgttcatat aggggttact actgaactta atatatggga tgcttttact ccaggaagac
    42721 ttgaccaaca tctaaatcct ttctatgaaa gagatgtaga aaatggaata ctagatagag
    42781 atagagcaca agaattactt gaatgtttat gggttaaatt taacaatcag ccagcaccac
    42841 caaaagttgg tataacatta aaagaaagta gcacatatac agattttgca aatataaaca
    42901 ctggtggaat aaatccagat ggtcaagatg gtgttaatga agttagttat ataatacttg
    42961 atgttatgga tgaaatgaaa ttgatacaac ctagttcaaa tgttcaaata agtaaaaaga
    43021 ctcctcaaaa attcttaaag agagcttgtg aaatatcaag aaaaggatgg ggtcaaccag
    43081 cattttataa tactgaagca atagttcaag agcttatgga agctggaaaa actatagaag
    43141 atgcaagact tggtggaacc agtggttgtg ttgaaactgg atgttttggt aaagaagcat
    43201 atgttctaac tggatatatg aacattccaa aaatacttga attaacatta aataatggat
    43261 atgacccaat tagtaaaaaa caaataggta ttgaaactgg agaccctaga aatttccaat
    43321 cttatgagga actatttgaa gcatttaaaa agcaattaca ttatatgatt gacataaaaa
    43381 tagaaggaaa tgctgtgata gaaaatatat gtgcaaaaca catgccttgt ccacttatgt
    43441 ctacaatagt tgatgattgt atagaaaaag gcaaggatta ccaaagaggt ggagcaagat
    43501 acaacactag atatatacaa ggtgttggta taggaactat aacagatagt ttaacagcaa
    43561 taaaatataa tgtatttgat aagaaaaaat tcgatatgga tacattgctt aaagcacttg
    43621 atgctaattt tgaaggatat gaagctatac ttaatttagt ttcaaataag actcctaaat
    43681 atggaaatga tgatgattat gctgatgaaa taatgcaaga gatattcaat gcatattaca
    43741 atgaggtaac tggtagacta actgtttgtg gtggagaata cagagtagat atgttaccaa
    43801 caacttgtca tatatacttt ggagaaatta tgggagcaag tccaaatggt agactttgtg
    43861 caaaaccagt ttcagaggga atttcacctg aaaaaggtgg agatactaat ggacctacag
    43921 cagttataaa atcttgtgct aagatggacc acataaaaac tggtggaaca ttattaaatc
    43981 aaagatttgc accatcagta gttcaaggag aaaaagggtt agataatatg gctaatctag
    44041 taagagcata ctttaatatg gatggtcatc atatacaatt taatgtattt gataaaaatg
    44101 tactgttaga ggctcaaaag aatcctaagg attataaaga cttaatagtt agagttgcag
    44161 gatatagtga ccatttcaat aatttaagta gaacactaca agatgagata ataggaagaa
    44221 ctgagcaaac attctaggtt tgcttgtaaa taaaacttct tactatataa aatcgtaact
    44281 gatataataa agtataaatg gtttgattcc atttttaaaa ttttagatta attatgagct
    44341 aactttctaa ataggaagtt agctcgttaa gtttaatgaa aaaatcgtta aatttatatt
    44401 tagtaaatca tacacatatt agtaagtaat acatacaaaa gaataattta ttatagttat
    44461 aataaggtta tattttataa aaataagata attttaagca gttaaaataa agtcaattta
    44521 gctactttaa aataaaacta atagaaaaaa ggagatttga tatgaaaact ttaggattta
    44581 ttggttcagg gaatatggga agtgcaatga taggtggcat agtacagtca ggattagtaa
    44641 aggcagaaga tataactgta tcagatttaa gccaagttgc cttagataaa gtaaaagaag
    44701 aatttggaat aaatactaca actgattcaa aggtagctgt tacaaattct gatgtggtaa
    44761 tagtagcact taaacctaat atatgcgaaa aggctttaac tccacttaaa gaattaatag
    44821 atgcaaataa aataatagta tctatagcag caggtaaaac tatagaaagt ctggaaagtt
    44881 ttataggttc agataaaaaa atagtaagag taatgcctaa tactccagcc cttgttggcg
    44941 agggaatgtc agctctttgt aaaaatagta atgtaacaga tgaagagtta aatatgatta
    45001 aggctctgtt tgaatctttt ggtgaggcag aaatagtatc agaatattta atggatacag
    45061 ttacaggtat tagtggttct tctcctgcat atgtatttat gtttatagaa gctatggcag
    45121 atgcagcagt attagctgga atgccaagac aacaagctta taaatttgca tctcaagcag
    45181 taatggggtc agctaagatg gttcttgaaa ctggaaaaca tccaggtgaa ttaaaagata
    45241 tggtttgttc tccagcagga actactatag aagctgttaa ggtattagaa gaagaaggct
    45301 ttagagcagc agttataaaa tctattgttg cttgtataga taagtctaaa gatatgagca
    45361 aataacagat gtaattaagt ttactatatg gtttcttgaa ttgttttttt agtacttatt
    45421 tatatctata cataaatgta tttggtataa gtaaaataag agtaatttac tataaaaagg
    45481 aatttaatga ttgagtgaga atttattact taaatattaa taattaaata gatatatttt
    45541 taactatatt tgagatatat cattgtgaaa aaataa
//
LOCUS       DAMJWO010000026        44809 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.027, whole genome shotgun sequence.
ACCESSION   DAMJWO010000026 DAMJWO010000000
VERSION     DAMJWO010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44809
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.027"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            70..531
                     /locus_tag="PC366_001461"
     CDS             70..531
                     /locus_tag="PC366_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2576992.1"
                     /translation="MQNSVKQEPCDFSHGRFRFGGKIIRRNEKTKFDWLSRDKEQVEK
                     YINDPFCGVVCSCGFFYDLVQGLKEIEDKENLKKVPLDIPIYIISGDKDPIGKNGKGV
                     LRLRDRYIKLGVKDVTCKLYKDGRHELLNEINREEVFEDIICWLNNKIEIL"
     gene            996..2210
                     /locus_tag="PC366_001462"
     CDS             996..2210
                     /locus_tag="PC366_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2576993.1"
                     /translation="MQIKIGKVIQRLRKERNLTQEQLAKFIGVSTPAVSKWESGNSYP
                     DIELLPLLADFFNVSIDKLLNYKIDLSEEKVMKIYKELESGFARIEIDLSTEEPKEEF
                     RQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRVKETTNILEDI
                     VRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKSIGDTSVNLAMIYLKQNRL
                     EEAEILLQNKLFSNIFNISMDCKGIINVYKNQYKELKKKLENRNFNKNAIEREMEYIK
                     NKLLWYANLSLEIKKMLSEDKGAFFSMYVDYMELSLIFLFFNMKEEAKKALYSLKEIL
                     EKYPIHESLDVSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELREEPIFKDVIEK
                     ILDMEKMLKNKE"
     gene            complement(2630..3151)
                     /locus_tag="PC366_001463"
     CDS             complement(2630..3151)
                     /locus_tag="PC366_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2576994.1"
                     /translation="MKFERLRTSENKLYYKAMELYKISFPFHEQRKSYLQTEILKNKE
                     YQFNLIYDKNQFVGIILCWETDNFIYVEHFCIFPEMRNNRYGQRALELLNKKGKTIIL
                     EIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHEKFNGHNLIVMSYPEKLSKMEYD
                     KFNHYLRNNVMSF"
     gene            3507..4304
                     /locus_tag="PC366_001464"
     CDS             3507..4304
                     /locus_tag="PC366_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HDF2576995.1"
                     /translation="MEKREKRIIISSLLSVSILMGLVSIYSILNKEDIILTVKGQEQK
                     VSSFKKTVEELLDEQGVKYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFD
                     TKHVNDSNLLKGKSKVYQEGQEGEKKLVYNLTYHDGKLVKKVLSKEVISKEPTTKIIK
                     YGTKEKVLIASRGANIRGGKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTK
                     VYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            4414..5004
                     /locus_tag="PC366_001465"
     CDS             4414..5004
                     /locus_tag="PC366_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDF2576996.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNEETRLEIVNKGINGDTT
                     SGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNEIINSNIMAMVHQSYSKNIIPIIG
                     IPLKPDIPNVREDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFADFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            5070..6767
                     /locus_tag="PC366_001466"
     CDS             5070..6767
                     /locus_tag="PC366_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDF2576997.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTH
                     YIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGISLYDGLIELYKK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKS
                     NVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKLK"
     gene            6981..7820
                     /locus_tag="PC366_001467"
     CDS             6981..7820
                     /locus_tag="PC366_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HDF2576998.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHE
                     MLK"
     gene            8337..10193
                     /locus_tag="PC366_001468"
     CDS             8337..10193
                     /locus_tag="PC366_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HDF2576999.1"
                     /translation="MDIHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGENTGKLFRDDYRGGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIIDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALINKIFESDKGVVENKKVVTFELNVSINDENKCIEITKRPFFD
                     SYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKKDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGIGSEFIVSLPVRSENNIEKYNHKREISNELSKKLEIEFSDL"
     misc_binding    10276..10516
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    10582..10817
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10902..12119
                     /locus_tag="PC366_001469"
     CDS             10902..12119
                     /locus_tag="PC366_001469"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HDF2577000.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRSIEIVGILVNNLEK
                     HKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            12233..12727
                     /gene="cdeM"
                     /locus_tag="PC366_001470"
     CDS             12233..12727
                     /gene="cdeM"
                     /locus_tag="PC366_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HDF2577001.1"
                     /translation="MENKKYANGGYSEDWYERGESTAKWFQNDREEYERAAYDEDRER
                     RGSNCGCSDSGGNRPRNCERFRREAEIREREAREAFCESSERKKEALAYECEARKLWE
                     EAEKYWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCN
                     CCRK"
     gene            12992..14257
                     /gene="hisD"
                     /locus_tag="PC366_001471"
     CDS             12992..14257
                     /gene="hisD"
                     /locus_tag="PC366_001471"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HDF2577002.1"
                     /translation="MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNI
                     ESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAI
                     QSLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(14460..15212)
                     /locus_tag="PC366_001472"
     CDS             complement(14460..15212)
                     /locus_tag="PC366_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2577003.1"
                     /translation="MSYFQYQGNSCFYKEYGQGKPIIFLHGNTGSSNMFKALVPLYVE
                     NFRCILIDFLGNGQSDRVSQFSPDIWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCHGKDWEN
                     VVNLDTKALLQCANKKRPLFHKELCKLEMPILFTGSKEDEMCRHNLEEEYKQMATFIS
                     KASIHIFSQGGHPAILTNADEFAQLAKVFFKY"
     gene            complement(15330..15599)
                     /locus_tag="PC366_001473"
     CDS             complement(15330..15599)
                     /locus_tag="PC366_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577004.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQNGMSIKQLSEKYFLTEKSIQRILKQQNL"
     gene            16074..17168
                     /locus_tag="PC366_001474"
     CDS             16074..17168
                     /locus_tag="PC366_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF2577005.1"
                     /translation="MKNIVGKPQTIKKVNEDLIKNIIKNEGPITKPEISSITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNCCIGVVANLL
                     GEIIYQEEFNIRMDTYENVNQDTFFVIDTLIKKEKGNNIRAIGIGVPGVVKKGVVKNI
                     PTIKSWEGINLENLIKSKYNTKVFIENDTNITTIGIYQKQYKDKYKNMALMYLEDGIG
                     SGIVINGELYLGSTNFAGELSYLNIEFGKYNSNNLNLEDYIMSLRKRYLESKDNKFKK
                     EILSIISNFIRTLVCVLNPQAMIIQCSILTKSDMEFIEKDVSNNVGEENFPKLIKVES
                     LRERSINGVISMCLKETDYQYSLSNKKGGY"
     gene            17170..18120
                     /locus_tag="PC366_001475"
     CDS             17170..18120
                     /locus_tag="PC366_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HDF2577006.1"
                     /translation="MKYLVSIDGGGTKTKFCVSDLDGNILKEHTTGSTNYKSVGIKKT
                     YENINNGLKKILKDLYIDYDDIEYTVFGISGCDSPNDYKIIMDEILKIGINKEKIYLA
                     NDAVLAFYAQADSPGLVIVAGTGSIILGIKEDGEIYRVGGWGYNFSDLGSGYDIGRKL
                     LKKVLLYCDECHEYSDLFSCVLDFFGANSFEQLAYMITDINNNVEIANLASLVIDCAE
                     QGDKLAIEILRESSTELSKLAQVILRKISNPMKIDKSEINIVLSGGTLNKTVYAQMLM
                     NNLKTENTDKNLKFISQENQPVYGGIRLAMALANRRVKHG"
     gene            18113..19297
                     /locus_tag="PC366_001476"
     CDS             18113..19297
                     /locus_tag="PC366_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577007.1"
                     /translation="MDRKKVIVQIFTGGFKAKEIKFNDIKCKLLELLDCIDIEKVIMG
                     WSVDEELYVETKKLLNKYNVELYLWLPCFSEIGLLEKSNLLIDYMGKEVKGYALQEDE
                     NFEFYCPNNKENIKNIKKIYSTYFSDIKFDGIFLDKIRYGSFSNKLNGVFNCFCKDCL
                     NIYEKNNIDKKSLMREMNNVSKGVIDNEDTPSGITEYINGKYKFKNKIWEDFFETKNQ
                     NIYKSLLEISSYFKSKGLKIGIDTFSPFISYFTGQDLKKLQEVADFIKPMMYRTTKAP
                     AGLPFEFERFIDESIHKNKEIGKRNFLDILGIKEYEGDVYPIEFVLEEIDFMTRNLNK
                     DIYVGVEINKKEIIAPVTPKYISENISNINKTTVKGYVLSWDLLSAPKENIDEIIKWF
                     RN"
     gene            19310..20806
                     /locus_tag="PC366_001477"
     CDS             19310..20806
                     /locus_tag="PC366_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDF2577008.1"
                     /translation="MSKILEMQQIYKSFGKVDVLKGINFELEKGEVRALLGANGAGKS
                     TLIKILGGVHSQTKGKVILTGNEIMFKNSHHSKENGISIIYQELSLIPTLTVLENIFL
                     GREILKGSVFLNKKDMLEEYMKICEDFDFNIDPHTVVSNLSVANQQMVEIMKAVSCNS
                     EIIIMDEPTTSLTNNEKDGLFKIISRLKSKGKTIVYISHILEEVFKVCDSASIMKNGI
                     MIGTYDVEDLTKLKITQLMTGNDNHKLIEKKDYTFAKYEEPPVLEVKNISWSNKIKNV
                     SFKVYRGEVVGLAGLVGSRRTEIINLIFGIDNKDSGDIFINGKKVDITSPKVAIKNKI
                     GLIPEDRKNLGLILEQAIYTNSSSVQIDKFKKFLFIDRNKEIEFSKKGVKELGIKVSD
                     VKQEVKELSGGNQQKVVVSKWLEKDLDLIIYDEPTKGIDIAAKEDIFNTIKEFSSEGI
                     GVIFISSDLEEVIRVSDRILVTREGSIVDDLKNENIQVQDIMNSIFNV"
     gene            20829..21779
                     /locus_tag="PC366_001478"
     CDS             20829..21779
                     /locus_tag="PC366_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577009.1"
                     /translation="MKKAFEKLNLRDYGVLLGFLALCIAISIATPSFLGKQNILNLLR
                     QSSIIGIISAGMTFVIISGNFDISVGAVAALAGAITMKFATGGTNLFASMLLGVAICA
                     VIGLINGIVVAKINVPSLIATMAMVTIVRGLLLMLTGGYPITENIPILDYIGNGYLFN
                     IPIPVVIFFIVVLVSFIVLNKTKFGRYVYSVGGNQEASKLNGINVDSHKVKVFIINAV
                     LAGIAGIVLTGRLGTATAIAGEGYDMDAIASVVIGGTSVAGGSGSVLKTVIGVLLMSV
                     INNSFNLLGIDVYFQYIFKGLIILAAVGFDSYSKKKLASR"
     gene            21800..22762
                     /locus_tag="PC366_001479"
     CDS             21800..22762
                     /locus_tag="PC366_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDF2577010.1"
                     /translation="MKKLMKHLALLLSLVMIFGLVGCSNGGDKEKNGEKKIAVLLPGS
                     TGYFVATKQGIDAKSKELGVSVEYADAQWDASKQLSQAEDFMAKGVDMIALCGVDSAV
                     SERIVKAANDSDVPIVAFTNSIGSNPTGEFKGLVTYIGQNEEETGALTGKIAKNLLGE
                     TGGKAVLIEGVPGTTPQVLRKKGLEKELKDSNIEIVYNQTSNWEKEQALKVTEDLIQK
                     KTDFNVIICQDDNSATGAGQALKDAGLKDKVKVIGLGGSKDGLKAITDGLIDGTTYMS
                     AVEEGGLVIEKASKFLKGEKIEPVTQIKQVEVNKDNISEFKGEW"
     gene            23134..23766
                     /locus_tag="PC366_001480"
     CDS             23134..23766
                     /locus_tag="PC366_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2577011.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            24177..24269
                     /gene="kdpF"
                     /locus_tag="PC366_001481"
     CDS             24177..24269
                     /gene="kdpF"
                     /locus_tag="PC366_001481"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HDF2577012.1"
                     /translation="MEGLPMWFLAVVIIMLIIYLVYALINPEKF"
     gene            24310..25992
                     /gene="kdpA"
                     /locus_tag="PC366_001482"
     CDS             24310..25992
                     /gene="kdpA"
                     /locus_tag="PC366_001482"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015391009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HDF2577013.1"
                     /translation="MFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDN
                     FIYKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGL
                     SFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKK
                     KTLGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGP
                     VAALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKN
                     KKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSS
                     LFTTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVF
                     LCGLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGF
                     HGLSQVLYEFASSAANNGSGFEGLGDNTMFWNITTGIVMFFGRYVSIIVLLAISSLLA
                     SKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            26017..28074
                     /gene="kdpB"
                     /locus_tag="PC366_001483"
     CDS             26017..28074
                     /gene="kdpB"
                     /locus_tag="PC366_001483"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HDF2577014.1"
                     /translation="METKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRAYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNVGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFIAVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGTVPEDLEENVNRVAKLGGTPLVVCVDNEIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQLE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMIL
                     NLG"
     gene            28093..28719
                     /locus_tag="PC366_001484"
     CDS             28093..28719
                     /locus_tag="PC366_001484"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HDF2577015.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNASYGGVSSGSFNY
                     GATNPELHDRVQKDIEKFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAI
                     AKASGISESKLQKIVDDNTSKKLFGVLGEDRVNVLKVNIEVAKILGLI"
     gene            28956..29864
                     /gene="cysK"
                     /locus_tag="PC366_001485"
     CDS             28956..29864
                     /gene="cysK"
                     /locus_tag="PC366_001485"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HDF2577016.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEQRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSVER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIRVIALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEVILVDDEDAFDTVKLLAAKEGILVGISSGANIFGAIEM
                     AKKYPDKKIVTVAPDGVDKYMSMGIF"
     gene            29891..30481
                     /gene="cysE"
                     /locus_tag="PC366_001486"
     CDS             29891..30481
                     /gene="cysE"
                     /locus_tag="PC366_001486"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HDF2577017.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVSYEYDELDNVYYI"
     gene            30641..30829
                     /locus_tag="PC366_001487"
     CDS             30641..30829
                     /locus_tag="PC366_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HDF2577018.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMKDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(30883..31752)
                     /locus_tag="PC366_001488"
     CDS             complement(30883..31752)
                     /locus_tag="PC366_001488"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HDF2577019.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEIGMSTEDMNKLVHDFTLQNGAIPAPLDYNG
                     FPKSVCTSVNNEVCHGIPSKDIILKDGDIINVDVSTIFNGYYSDASRMFMIGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDAINSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
     gene            complement(31949..33193)
                     /locus_tag="PC366_001489"
     CDS             complement(31949..33193)
                     /locus_tag="PC366_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577020.1"
                     /translation="MENNLNIAKKNNTELLQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEKANRKISIYDMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLDEIYIDLKQAYLYIKKNTDSLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILDLEDIHSYYMENNTNITIYENNTLQYKFDEESEDIKDSSI
                     DIIEQMLILPDDLNYDKDEVENMKSRLAKINIKYLQTLKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYANVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMEVFAQERYKLYDPKQVAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELNY"
     gene            33484..33795
                     /locus_tag="PC366_001490"
     CDS             33484..33795
                     /locus_tag="PC366_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDF2577021.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGINSKYTRAKGFE
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPSILINLIDNKEDYIIGKEIEQL
                     T"
     regulatory      33888..33980
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            34080..34874
                     /gene="thiD"
                     /locus_tag="PC366_001491"
     CDS             34080..34874
                     /gene="thiD"
                     /locus_tag="PC366_001491"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HDF2577022.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVENLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNLSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            34898..35686
                     /gene="thiM"
                     /locus_tag="PC366_001492"
     CDS             34898..35686
                     /gene="thiM"
                     /locus_tag="PC366_001492"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HDF2577023.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVRGKGVDSFDEEEDSTEIIRKIAEKLECVVV
                     ATGKIDIITNGKGIYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLT
                     MSLSGELANLNNPPIGTFKENLMNAIYQMDIDTLSKNSNIEFLN"
     gene            35709..36341
                     /gene="thiE"
                     /locus_tag="PC366_001493"
     CDS             35709..36341
                     /gene="thiE"
                     /locus_tag="PC366_001493"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HDF2577024.1"
                     /translation="MIDKESLKKCLKLYLVTDSEMLKGRDFYKCLEDAISSGITTVQL
                     REKNASGREFLRKAMKLREITERYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGNNKILGVSARTLEEATCAKNDGADYLGVGSIFTTSTKLDAKSASFETVKEIKEK
                     VDMPFVLIGGINLDNIDKLKCLESDGYAIISAILKAEDISKEVEKWTLKI"
     gene            36480..36782
                     /locus_tag="PC366_001494"
     CDS             36480..36782
                     /locus_tag="PC366_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2577025.1"
                     /translation="MIKILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMLDDVKSIVGDRVPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(36848..37597)
                     /locus_tag="PC366_001495"
     CDS             complement(36848..37597)
                     /locus_tag="PC366_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577026.1"
                     /translation="MLNILWRSMKWRFKNPISFVVTILQPFLWLVLYSSIANQTMNNI
                     NINNYTAFILPGIIVLVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQLLE
                     AILVSFIEVTILCIVSIFFSVRIESGIGGILLMIVLIFMTAFFLSSLAYSISLLLPNE
                     IVYETIMTAIVLPIFFLSSALFPIESLSGGLKVAVMLNPFTHVINALRSLIFGETILI
                     GDILPVILLFLILCCSSFSLAMWRLKKEMVS"
     gene            complement(37591..38553)
                     /locus_tag="PC366_001496"
     CDS             complement(37591..38553)
                     /locus_tag="PC366_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577027.1"
                     /translation="MLAIEIDNLVKEYKNGVKALNGLSFNVNAGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVKMFGKDLVDNPSWIRTQIACVAQQISIDEHLSLMENMVFQS
                     KMYKVEPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRDEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNILRITFHNTEDIKKYKDSIKSTGLVKFMSVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEEWEC"
     gene            complement(38557..39015)
                     /locus_tag="PC366_001497"
     CDS             complement(38557..39015)
                     /locus_tag="PC366_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDF2577028.1"
                     /translation="MNCKIEIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNG
                     APFFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHTGSYSNLPKT
                     YEMIFKYIHENNIKIQTPWREVFIKGPGMLIKGNPDNYITEIIFPLKEEE"
     gene            39371..39727
                     /locus_tag="PC366_001498"
     CDS             39371..39727
                     /locus_tag="PC366_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2577029.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVTGELKPGETIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNYQSSVTVDENILKNLKLELINESLSVFIEDMKA
                     INVSKEEVLKIIEDKY"
     gene            39799..40515
                     /locus_tag="PC366_001499"
     CDS             39799..40515
                     /locus_tag="PC366_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577030.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINIDSGEIRIDGEKINEKVYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKEKSKEMMDIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVVILDEGQIITSFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            40508..41332
                     /locus_tag="PC366_001500"
     CDS             40508..41332
                     /locus_tag="PC366_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577031.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLSLNLFEINKFKNS
                     KFIMNLAIEDFGGIFYGLGILSNLGFIQNILFFGMLGLFIYYIFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIVLITMIYGFLISQTATLFICKYIFNFIFRNIPIINMNFAK
                     DLYYLNLKSIPIDFISFMAIYVFLLLIAISIVNCCILFIFSYINKFYVILITLLIIAG
                     LYFSTIYINIINLFRKYYNLIGFQFNNLVAGLLSFLIIMFILNGISYLLIKKKVSL"
     gene            41344..42543
                     /locus_tag="PC366_001501"
     CDS             41344..42543
                     /locus_tag="PC366_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577032.1"
                     /translation="MKLKSKISILIIFLTLAIYFSIGLLNNEDNLKIKTIKGDSNELD
                     HININFGYALNGYINSYYTINGSNKTKKTELIKLQKDSKNTNNLIDVSSGSDLIAHVG
                     FEMNEESKDINFVIDEKKEDLEKGVFPSEGSDKEIEYEKLDMNNFTRTRYKVDKSTDD
                     YYANILASKRYKKYLYVSVLYATSDSSENNKEYSSTIDIIKINPENKKIKTIKSINLS
                     NYFSEKYQDIENIGVSYASKYEDKMYILVNVLNTNIGDNSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKAKLEANKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYVLDN
                     REKRGIRSIEIDSNKIVAYTSRLNSILSWDNKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            42552..43364
                     /locus_tag="PC366_001502"
     CDS             42552..43364
                     /locus_tag="PC366_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577033.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVNVTGFSSFRNIMGSTESWFIFGIIACICYAFFIWYRDF
                     NGRSKSIYTLIMLPKNRINIYISKLLNILFLVYSYTVVLTISLFIASKLLPRHMLGNV
                     TNYGFVQETIYELKMLLPYSFEILFVEYIFLLIGFVSVVFTSILINKSIYKVSTLISF
                     LFLVLEILVFIISIEFIIPYEYSDVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            43375..44643
                     /locus_tag="PC366_001503"
     CDS             43375..44643
                     /locus_tag="PC366_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577034.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPNISKFSYEEVIISKNGVRNNKNPKSRIRNDYLNIDKKYSDFVNDKG
                     KELIYKDDLNIGEAYTSVKSDLVQGMNALNDCIKVSNKNLKSGVEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNISGSKVNNICILKIDIKNKSYKLLNRFNLGLQNG
                     YQQNINEIKFSIGSKLYLEIVNNKSKNGDIEGHDSYSNLIIYDIEDNTFNISNKFMDN
                     LNKEKNANPKEIGLLSKTKLDYMIKNNKLNLIVTDMSNSIINLVYDINSNEIKLEDYE
                     ILDLKVDYNEASSGVRKVKLLDDKIYSISGMKNSISGELKGFKGIVDVVGTKPVKFQV
                     FDMKLKKNIYEAELINGDISLQEKLFFVAN"
BASE COUNT        17534 a         4657 c         7706 g        14912 t
ORIGIN      
        1 aataacttat gtaagaaccg taggaactac ggggatagcc tgtggagaat tagtaagaca
       61 tattttagta tgcaaaattc tgtgaagcag gaaccctgtg actttagtca tgggaggttc
      121 agatttggtg gcaaaataat aagaagaaat gaaaagacta agtttgactg gttaagtaga
      181 gataaagaac aagttgaaaa atatataaat gacccatttt gtggagtagt gtgtagttgt
      241 ggcttttttt atgatttagt tcaagggtta aaagaaattg aggataaaga aaacttaaaa
      301 aaagtgccac ttgatatacc tatttacata atatctggag ataaagaccc cataggaaaa
      361 aatggtaaag gagtcttaag actaagggat agatatataa aattaggagt aaaagatgta
      421 acttgcaaac tttacaaaga tggaaggcat gaattgttga atgaaataaa tagagaagaa
      481 gtttttgagg atataatttg ttggttaaac aataaaatag aaatattgta ataaaaaaat
      541 ataatgatat atttgcttta aatttattta tatataatat ttgaaaagtg gattatgtat
      601 atgcaaagta gaaaagagag agcctagaag tgattttttg ctataatgcc atttattgaa
      661 taggtgggtg ttattataaa taaattatta acactcagta ttattatcat tgtatatgga
      721 atttatttta tttaaaattc cttgaaagtt taaatatagt aagttgtagt aaagagaaaa
      781 tctaaatatt taaatgctat ttaatgtgaa tctattaatt aggttatact taaacttaat
      841 taatagattt tatatttcaa gccaatgaga tagggtttta gattaaaata taaccaatgg
      901 ttaaattaca gacattttgt taactttccc tcgatttact agtaaatatt ttttttatat
      961 acttaaatta caacagatgt actagggagg tatatatgca aattaaaata ggtaaagtca
     1021 tacagcgtct tagaaaagaa cgaaatttaa ctcaagaaca attagcaaag tttataggtg
     1081 tgtcaacacc agcagtatct aagtgggaga gtggaaattc ttacccagat atagaattat
     1141 tgcctttatt agcagacttt tttaatgtgt ctattgataa gcttttaaat tacaagattg
     1201 atttaagtga agaaaaagta atgaaaattt ataaagaatt agaatcaggc tttgctagaa
     1261 ttgaaattga tttatcaaca gaagaaccaa aagaagaatt tagacaagac ttagaatctg
     1321 taaaaaagct ttctaatatg tatatagaga agtatcctaa aagctattta ttgaagctaa
     1381 ggatatgttc gctgtatcag atgtattcat ataaatttgg taagagtgaa cttaatgaca
     1441 gagtaaaaga aacaacgaat attcttgaag atatagtgag aaatacagat gatatccaaa
     1501 taaaagaaac agctcttatt atattatcaa acgcatattg tatgttggaa gattatgaaa
     1561 aggcagagtt gtatttaaat atgatacata agtcaatagg ggatacaagt gttaatttag
     1621 ctatgatata tttaaagcaa aatagacttg aagaagcaga aatattgctt caaaataaat
     1681 tgtttagtaa tatatttaat ataagcatgg attgtaaggg aataattaat gtatacaaaa
     1741 atcaatacaa ggaattaaag aaaaaattgg agaatagaaa ttttaataaa aatgcaattg
     1801 agagagaaat ggagtatata aaaaataagt tgctgtggta tgcaaatctt tctttagaaa
     1861 taaaaaaaat gctcagtgaa gataaaggtg cattttttag tatgtatgtg gattatatgg
     1921 aattatctct aattttttta ttttttaaca tgaaagaaga agcaaaaaaa gccttatata
     1981 gtctaaaaga aatattagaa aaatatccta tacatgaaag tttggatgta agtcaaatga
     2041 gattttttga taaggtagag tctaaaaatt tatatacttt taatatatat acaaacttgt
     2101 taattgtact taatgatgac agttataatg agcttagaga agaaccaatt tttaaggatg
     2161 taattgaaaa gattttagat atggaaaaaa tgttgaaaaa taaagaataa gtaaaaattt
     2221 aatataggac ttaaagatta atcaaattaa aagaaagtgt ttcaaaataa aaatttgaat
     2281 cacctttttt gttggtctta aaccgttatt tagaaaaata gaggtttcaa aatagaaatc
     2341 tgaattatct gtattattac acaaaaatag aaacctaaat ttataaaaat agaataaagt
     2401 ttgttatata aaatgtaatt ttgtctataa aatctcacat gttttcttaa ctttaagcgt
     2461 gaaaaagagg atgtatcatg aattttttag ttcatgatgc atccttattt gtatgaaatc
     2521 caatatatct ttattattta aacaatggaa aagagtctta tttctatttt gagacatctc
     2581 ttttatttaa ttatgaagtt ttatacagtt caataaatag gaattatatt tagaaactca
     2641 tgacattatt tcttagatag tgattaaatt tatcatattc cattttagat aacttttctg
     2701 ggtaagacat tacaatcagg ttatgcccat tgaatttttc atggtatggt ggatgaatgt
     2761 gttcataatt atttgtctta tattttactc tttcatagaa cgccttgcga taaattgaaa
     2821 tctcatcaat tggaaggtca atttctaaaa taatagtttt tcctttctta tttaaaagct
     2881 ctaacgctct ttgtccatat ctattattgc gcatttctgg aaaaatgcag aaatgttcta
     2941 catagataaa gttatctgtt tcccaacata aaattatgcc gacaaactgg tttttatcat
     3001 aaattaaatt gaattgatat tctttatttt tcaaaatttc tgtttgcaaa taagattttc
     3061 tttgttcatg aaatgggaaa ctaattttat ataattccat agccttgtaa tataatttat
     3121 tttcactggt tcttaaccgt tcaaatttca ctttactcct cctaatcacg aaaattccaa
     3181 tttatttatg agttcatttt accatagtca gtatttgcat acaatgtgtt ttaagttgag
     3241 tgtcatttct ttcttttatt tatgcttata tctcatagac taagagataa ttgcttaaga
     3301 cataactaaa aactattata ttaagctttg ataatctaaa aacagtatat ttatggactt
     3361 ttctaggtct aaaagtaatc ttaataattt tagaagttac aaaaaagtta cataaatttg
     3421 gaaagctata atatacatat ataatataag gttaaaactg taatgaataa tattaattta
     3481 aaatttgaac atggaaggag attattatgg agaaaagaga aaagaggata ataatatcat
     3541 ctttattaag tgtatcaatt ttaatgggtt tggtaagtat atattctata ttaaataaag
     3601 aagacataat tttaactgtt aagggtcaag agcaaaaagt atcttccttt aagaaaacag
     3661 ttgaggaact tttggatgaa cagggtgtaa agtataattc tgaagataag attaatccaa
     3721 gtttagatac agaactaaaa gatgatatga aaataaaagt tgttaaggta actaaaagta
     3781 aaaaagaaga gattgaaaaa attccatttg atacaaagca tgtaaatgat agtaatttgt
     3841 taaaaggaaa atctaaagtt tatcaagaag gtcaagaagg agaaaaaaaa ctagtctata
     3901 atttaactta ccatgatgga aaattagtca aaaaagtctt atcaaaagaa gtaatatcta
     3961 aggagccaac tacaaaaatt ataaaatatg gaactaaaga aaaagtacta atagcatcaa
     4021 gaggagcaaa tataagagga ggcaaacata tgaaagtggt tgccactgca tatgcaggag
     4081 atacaataac atctactggt acaactccaa gatggggtgt tattgcagtt gacccacgtg
     4141 taataccata tggaacaaaa gtatatatac ctaaactggg tatgactttt gtagcagaag
     4201 attgtggagg tgcaattaaa ggtaatagaa tagacatttt tatgaacagt gaaggaaaag
     4261 cttcaaattg gggaaggaaa agtatagata tatatctaca ttaaattagt gaatagaata
     4321 actttacttg aaggacaaaa aagtataaaa tatgaattaa ctaaactgtt agattattct
     4381 taaaacataa aaatatatct aaggggggat aagatgaaaa tagtctgctt aggagacagt
     4441 ttaacgtatg gatttggagt atcacgaagt aattcatgga caaacattgt aaatgaagag
     4501 actcgattag aaatagtaaa taagggtata aatggtgata caacaagtgg tatgttagct
     4561 aggtttaatg aagatgttgt aaaaaactct cctgatatag tttttataat gggtggcact
     4621 aatgatttta ttgctggtgc gggaaatgaa attattaatt ctaatataat ggctatggtg
     4681 catcagtcat attcaaaaaa tattatacct ataataggta taccattaaa accagatatt
     4741 ccaaatgtta gggaagattg gagttgtttt actgatttta atatagtatc tcaaaactta
     4801 gaatcatata gttattggat aaaaaaattt tgtatgacat ttaatactaa tttcgcagat
     4861 ttttattcag aatataataa aaatatggaa ctagaaggat ataaaaaatt atattttgat
     4921 gggttacatc caaccaaaga gggtcataga ataatggcag acatttttat taattcaatt
     4981 aataagtata tagaagagtt atagattaca ttaaaatgct tgtttatgcg tcagttgcaa
     5041 taaatacata cagtagagag gggtttatta tggattatac taaaacttat gaagagtgga
     5101 taaagggttc atattttgat gaagatacaa agctagagtt ggagaatata aaaaataatg
     5161 aaaaagaaat agaggataga ttctataagg atttagaatt tgggactgcg ggtcttagag
     5221 gaataattga agcaggaacg aatagaataa ataagtacac agttagaaga gctacttttg
     5281 gattggcaaa ctatatatta gaaaacacaa caaaagaaga aacaagtaga ggagtagtaa
     5341 tagctcatga taatagacac aagtctagac aattctgtat agaatctgca aatactttgg
     5401 cagcatgtgg tataaaagca tatatatttg atagtttgag aactactcca gaattatctt
     5461 ttgctgttag aagcttaaat gcaatcgctg gtatagtcat aacagcaagc cataatcctc
     5521 cagaatataa tggatataag gtatactggg aagatggagc acaagttatg ccagagattg
     5581 caaatgcaat aacagagaaa gtaaatagta tacatgatta tagtacaata ccaaccttaa
     5641 cggaagctaa taaaaatttg gtagttttgt tggacgaatc acaagatact aaatttatag
     5701 aagcagtaaa aagccaaatt ataagaaaag atttagttaa aaatgtaggt aaaagcttta
     5761 agatagttta tacacctctt tgtggaacag ggaatgttcc aataagaaga gcattgaaag
     5821 aagttggttt tgaaaatata attgtagttc cagaagaaga aaatccagac ccaaattttg
     5881 cagggcttga ttatccaaat ccagaagaga aaaaagcttt aaatagaggt atattactcg
     5941 caaaagaaaa aggagcagac cttgtaatag caactgaccc agattgtgat agagtaggtg
     6001 tagcagtaaa aactactaca ggtgagtatg ctttacttac aggaaatcaa attggtggta
     6061 tgctgacaca ttatataata gaaggattaa aagaaaataa caaattaaaa gaaaatccta
     6121 caataataaa aaccatagtt acatcagaat ttggagcaga tatagctaaa gcaaataatg
     6181 ttgatgtatt aaatgttctt acaggtttta aatttattgg tgaaaaaata aaattatttg
     6241 aacaaaataa aaatagaagt tatgtatttg gatatgaaga aagttatggt tacttagttg
     6301 ggactcatgc tagagataaa gatggtgtag tttcttcatt gttaatatct gaaatggcag
     6361 cattttacta ttcaaaaggt ataagtttat atgatggttt aatagaactt tataaaaagt
     6421 atggattttt caaagaacag actatatctt tgactttaaa aggtatagaa ggtgtagaaa
     6481 agataaaaga aataatatct tattttagag aaaatcaaat tgattatata aatagtatta
     6541 aagtagttga taaaaaagat tataaaaatg gtatagataa tcttcctaaa tctaatgttt
     6601 taaaatactt tttggaagat gaatcttggg tagctataag accatctgga acagaaccaa
     6661 aacttaaatt ttacatagct gtaaaaggag ctagtgatat tgaagcagat aaaaagattc
     6721 aaggtttgaa aaagtatata gatgacatgg tcgaaaaatt aaaataaaat attattattt
     6781 tataagataa ttttgtaata atatttattt agctgaaaat tataatttac tttcattgag
     6841 tagaatatgg aaatgttagt agaattgtta ttttcagctt ttatttgtgt tatttttact
     6901 taaataatta tattatagaa tgaatctgag tataattaat attgtataat gaaattaatt
     6961 tgatagaaaa ggggatattt atgtttggta tagataagaa attgattgaa tatataattg
     7021 caaaatccaa ttacagtgaa ttaagttcaa agtcagcaga agtatctttc ttcttaatgt
     7081 tgtccatatt tcctttttta atatttacaa taagttctat agcttatata ccgattcttc
     7141 atttaaataa gtatatagct ttgtttagaa atatgatgcc agaaggtgct tttgctgtgt
     7201 tatcttcaat catagtttct gcaatagaca atagaaacct gaaattttta gcagtcagtt
     7261 ttgtacttac tatgtggaca ttttcaagag cagtaaaagc tcttattaaa ggaatgaata
     7321 gagcctataa agttaaagaa actaggtctt tttttaaaat tttatctata tcatttttat
     7381 ttacaataat gcttttggtc cttatttttt tatctatgat atttttagtt tacggggaaa
     7441 aaataggtta ttttattttt aatcttgtag gattggatga gatatttata aaaatatggg
     7501 atattctaag atacactgta ggtataataa caataatagt gatatttaca cttttatata
     7561 aatacactcc aaataaaaag ttaactatta aagaatctgc gccaggtgct atttttgcta
     7621 cttttgcttg gtttttagta tcatttttat attcttatta tacaaattac tatgctaact
     7681 atgaagtaat ctatggaagt atagctgaaa taattgtact tatgacctgg atgtatttta
     7741 gtagttggtc tatcgttatt ggctatgagg taaattcaag attgtatttt agaaagataa
     7801 gacatgaaat gttaaagtaa agtatttaaa ataaaagaga gtatttagta ttataaatgt
     7861 aattgaatta ataaagaaat attgacattt aagttaaaaa gtctagaatt tttctgggct
     7921 ttttttattt ttagtataac ttgacaaatt ttatttaatg ggatagtttt aatttataat
     7981 catctttgaa aagatgacta ttgataagta aggtataaaa ttggtaagta tcaaaaaata
     8041 tactaaataa aaattatagt cctaatgagt taatttctgt attttcaaat aatgcagtat
     8101 ttagtcatgt gtttttatat gcgcctgtat ttccaattac caatatatta gaataagcta
     8161 ctgtaattag atttagaaaa aagcgacata aataattata aacaaataat aaattacata
     8221 aaattaaatt tattcacaag tatatcttat aaaatatgtt ataattaata gaaaattgtc
     8281 atataattaa ttaagtagta ttattataaa taacattgaa aggtagtggt tagaatatgg
     8341 atatccataa taaatatgta aattttataa aaaatatacc tgtacctttt ttatattgta
     8401 gaattgtaaa gagacaagaa gatatagaat atcgagtaga atatataagt aagggtatgg
     8461 gcaaagtatt acaattagaa gaaggtattt gtgataaaaa tatactagat gtattgcctg
     8521 tatttaagtc taaaaaatat ttcaaagagt tgttctcaaa tgaagtggat tgtataaaaa
     8581 ggtacattcc gacacttaaa aactggataa atataaaaaa acagataata ggggattcat
     8641 acataatttt gtattttggt aaaattgtat ttgattatag acagataatc gattcctttg
     8701 ataaaaagga aaaagtagct tatattaaag acgaagaagg catatatata gattgcagtg
     8761 aaaatttaat accaatatta aataacaaca ttaaaacaac gaaagatatc tttggtaaaa
     8821 atgatataga agtatgggga gagaatacag gaaaattatt tagagatgat tatagaggag
     8881 gagtatctag taaaaaaaga tttttacaaa atctttttga atatgaagaa acatttttta
     8941 tggttgaaaa atattttttg tatgatgaag acgaactttt aggtactata gggataatag
     9001 ataatataat atatagtggt tacagtaata gaaattataa ctcaaaagat ttaatgaaga
     9061 tgatagaaca ctcaattcca gagaatatgt tttataaaga tgtgtatgga aattatattg
     9121 gatttaattc aggttttttg aatttagctt gtatgaataa agaagaatta ttagggaaga
     9181 atagttataa aatatcagaa gaagaagctt taataaataa gatatttgaa agtgataagg
     9241 gtgtagttga aaataaaaaa gtagttacat ttgagttaaa tgtaagtata aatgatgaaa
     9301 ataagtgtat tgagattaca aaaaggccgt tttttgatag ctatggaagt gttattggaa
     9361 taattggaac agcaagggat ataagtagaa gaaaaagatt agaagaggaa atggataaaa
     9421 ctaggatgga attttttgca aatttatccc atgaacttag aacgcctata aatttaatat
     9481 catcttcatt acaagtgata gaaaaaaaag aagcagattt aatagaatca aatgatactt
     9541 taaaaagaaa tttaggtata ataaaacaaa atggaaatag aatactgagg ttagtaaata
     9601 atgttataga ctttacaaaa atgcaatcag gatatttaga ttttaaacca gaagaatctg
     9661 atataattgc atttatagag gagatatgta tgtctgtagc tgattttgca agccaaaata
     9721 atatacaact tacatttgat acagaaatag aagaattttc aatgttattt gattcagaaa
     9781 aattggaaag aataatatta aatttacttt ctaatggaat taagtacaat aagaaagatg
     9841 gaaaaataaa tatattttta tatgtgaaag ataatgtatt taatatgaaa atatctgata
     9901 gtggaatagg tataccaaaa gaaaaaatag ataaaatatt taatagattt gaacagattg
     9961 acaatgaact ttcctacaga gttaaaggaa gtggtattgg actttcatta gtgaaatctt
    10021 tggttgaatt gcatgaggga agtatatctt taaaaagtca acttggtatt ggaagtgaat
    10081 ttatagtttc attacctgtt agaagtgaaa ataatattga aaaatataat cataaaagag
    10141 aaatcagcaa tgaactaagt aaaaaattag aaatagagtt ttcggattta taagtttaaa
    10201 tataaaaaat aaaattttaa aaaagtattg acaattgatt tagaagggtt taaaataaat
    10261 tacaacataa taaataaaaa ggcgatgaat aggaagagta aatctaattc gattaccaga
    10321 gagaagagtc cattggctgg aagacttttt aaattagagg gattgaaaac tacctaggag
    10381 ctactttctg aagtcatctg cattagtaga ttttagtaag aatagtcgtt agctgcgtta
    10441 aagtgtaaag tgagttttca tgatatatga aaactaaatt aggtggaacc gcgggaataa
    10501 tactctcgtc cttatgttat aaggatgaga gttttttgtt gtttaaaaat ataaacagta
    10561 atcataataa ttatagaaaa tataaaagcg atgaatagga agagtaaatt taattcgact
    10621 atcagagagg aaagttcaca ggctgaaaga ctttctaagt ttgagaaatt gaaaactacc
    10681 taggagctgt ggtctgaagt tactttaaaa agttttagta agactaaccg ttaactgcgt
    10741 taaagtgtaa agtggatttt atcaataaat gataaaatca aattgggtgg aaccgcgagt
    10801 atagactcgt ccctttatat agggatgagt ctatttttat tgcaataaaa gattgaaaat
    10861 aaaaaaaaat cggaaaatta taaatttagg aggaaaataa aatggaaaat aaagtgaaaa
    10921 ttggagtact aggatatgga gttgtaggaa gtggacttat agatataata gataataata
    10981 aagaaaaaag aagtatagaa atagttggaa ttttagttaa taatttggaa aaacataagg
    11041 ataaaaaata ttctaatata ataactaata atatagatga tatatttaat aaagatatag
    11101 atatacttgt tgaagtcatg ggtggtttag aaccatcatt atcttatata aaaaaagcat
    11161 taaacaataa aattcatgtt gttacagcaa ataaagattt gttagctgaa tgtggagatg
    11221 agcttgcaaa attagcaagt gaaaataaag taagtattaa atttgaagct tcagtcgcag
    11281 gaggtattcc agtattaaaa ccaataatag aatcactaga aggaaataat atagatagta
    11341 taaatgcaat tttaaatgga actactaatt ttatattatc taaaatgtat gatgagaatc
    11401 tatcttatga tatggcatta agacaagctc aagaattagg ttttgctgaa gcaaatccag
    11461 agtcagatgt attagggtat gatgctgcta gaaaactatc aatattatca actctagctt
    11521 atgacaatag agtatattgg aaggatgtgt atttagaagg aattacagat atagatgaaa
    11581 aagatattga atatgcaaaa aaattaaatt gtaaaataaa attgattggt caaagtaagt
    11641 atgaaaatga taaagtaagt gcttttgtta gacctgtttt agtagaaaaa gataatatcc
    11701 ttgctagaat agacaatgag ttcaatgctg tcatagtgaa tggagattca gtaggagaag
    11761 tttcttttgt aggtaaagga gctggaagtt tagcaacagg aagtgcggtt tattcagatg
    11821 ttatagatat aatagataat agagtttcaa gtatagattc ttttactaaa gataaaatac
    11881 aagttaataa aatagttaga gaaaagtgtg gagcacttct tagatttaaa aaatgtaata
    11941 aagatgaaat tctaaatata gttgagaatt gtttagtaaa attcgatatt ttaaatgatg
    12001 atgatgaact tgctattatg gtttatgctg attctgaata tgaaataaac aacagtttat
    12061 gtctaataaa agataaagga tattgcgaaa aaatgaataa aatgttgaaa ataagttaaa
    12121 aaagaaaaaa taagtttata tgtaacatat tttgacgatt ttaatactat atagtatgag
    12181 atgaaacaaa acatctcata aaaaattaaa attcaaggga gagatatgtt atatggaaaa
    12241 taaaaaatat gcaaatggtg gttattcaga agactggtat gaaagaggag aatctacagc
    12301 taaatggttc cagaatgata gagaagaata tgaaagagca gcatacgatg aagatagaga
    12361 aagaagaggc tcaaactgtg gatgttcaga ttcaggagga aatagaccta gaaactgtga
    12421 aagatttaga agagaagctg agataagaga aagagaagca agagaagcat tctgtgaatc
    12481 ttcagagaga aagaaagaag cactagcata tgaatgtgaa gctagaaaat tatgggaaga
    12541 agcagaaaaa tactgggatg aatattcaaa atacaactat aaaggaatcg aatatttagc
    12601 agaagctgct agattatttg atgaaggtat ggaatgtgaa gctagaagaa atggaaataa
    12661 tggaggaaac aataataatt gttgccataa atgccataaa tgtaattgta actgctgtag
    12721 aaaataaaaa aattcattga caaatcaata gttaaaatat atcatattat gtataataaa
    12781 gagaaaattc agaaaaaaat aatgattaga ataaatttaa gtatatttat tagacaaata
    12841 gtgctcagtt agtgaggtga gtacaatatg attaaactcc catcctctag cttttgatag
    12901 agggtgggag tttttattta ttgatatatc ttaaatgagg ataatattgt aaaataaatg
    12961 agtatgagat tgtaaaatta ggaggtaaaa aatgaaaagt attaaaacat caagtatgaa
    13021 agaaaaggta gatgaaaaga tattaagaga gcaagtaagt tctataatag aagatataag
    13081 aaataataag gatgttgcac ttaaaaaata taatgagaag tttgatagaa atacaagaga
    13141 tgaatttaga attactaagg aagaaataaa ggaagcttat aagcatgtag atgacgaatt
    13201 tataaataac ttaaagattg ctgccaaaaa tataagagaa tttgctaaag ctcaaaaact
    13261 aagttttgaa aacccttttg aaaaagaaat ttatccaggt gtaatcttag gtcaaactaa
    13321 tattccaata gagtcatgtc ttgcatatgt tccaggaggt cagtatccat tgttttcaac
    13381 agctcttatg cttataatac ctgcaaaagt agcaggagta aaaagaatag tggcatgttc
    13441 accaactatg aaaaatactg aaaagataaa tcctaaaaca ttggtagcta tggatatagc
    13501 aggtgctgat gaaatatatg caactggagg agttcaagct atagcagcat ttacatatgg
    13561 aacagaaaag attaatccag ttgacataat tgtaggacca ggaaataagt ttgtaactga
    13621 agctaaaaga caatgttatg gacaagtagg aattgatttt gtcgctgggc caagtgaagt
    13681 tcttataata gcggatgaaa cttcaaatcc agtttatatt gcagctgatt tattagcaca
    13741 atgtgagcat gatttaaatg caagaggaat attattgaca aatagcttgg aagtagcaca
    13801 aaaagttgaa aaaaatatag aaagtatgct aaaagatttg ccaacaaagg acatagcata
    13861 tagttcatgg gaaaataatg gagagataat attggttgat gatatggaag aagccattaa
    13921 aataagtaat ttttatgcac cagaacattt agaagttgca gtaaatgagt ataatgatat
    13981 ttgtgataga ttaactaact atggttcttt atttattgga aatctttctg ctgaggtgtt
    14041 tggtgactat gtttcaggta ccaatcatac attaccaaca cttaaagcat caagatatac
    14101 tggtggtgtt tgggttggaa cttttatcaa aacttgtaca aagcagatat ttaatgaaaa
    14161 agctatacaa tcattagcac ctgtagctga aaagctggca aaagaagagg gattatatgc
    14221 acatgcaaag gctgctgagg ttaggtttaa aaagtagtaa aaaattttat tttggcagtc
    14281 gagatttagt attagactga gataaagaaa acgctgagaa cctgaataaa tactatattt
    14341 tgtgggcctc ggcgtttctt ttatatctgt atataatagg ataatactac ctgtgtgttt
    14401 aaatgctaac ttaatatttc ttttctaaat aatgtttatg aaatagttaa tatttttagt
    14461 taatacttga aaaaaacttt tgctaactgt gcaaattcat ctgcatttgt caatatagca
    14521 gggtgtcctc cctgactaaa aatgtgaata cttgcttttg aaataaaagt tgccatttgc
    14581 ttgtactctt cttcaagatt atgacgacac atttcgtctt ccttacttcc tgtaaataaa
    14641 attggcattt ctaatttaca caattcttta tgaaataaag ggcgtttctt gtttgcacat
    14701 tgcaatagag cttttgtatc aagattaaca acattctccc aatcttttcc atgacaccat
    14761 tcatagaatt ttcgtgcttg aatatcttgc tttgattttt cccttccagt gattagatta
    14821 tctatgaagt tatcattaag agtacgtcca tcaaagctat ctgctataat tgcttcaact
    14881 aaatcgggac gttctaatcc agtattaaca gctgcccatg ctcctccact tgttccaatt
    14941 aagccaactt taccacaatt caaatgttca atcagtgcta ttgtctgtaa ggcttcatca
    15001 tgccatatgt caggagaaaa ttgagaaact ctatcagact gtccattacc taaaaaatca
    15061 attaagatac atctaaaatt ttctacatat aatggcacaa gtgctttaaa catattagaa
    15121 gaaccagtat taccatgcag gaaaattatc ggtttacctt gtccatattc tttataaaaa
    15181 caagaattac cttgatactg aaaatatgac atatattttc ctccttttta tttgttaagt
    15241 taattataac aatataggta tgaatgaaaa acctcatgtt ctttcttaga ataaaaatgt
    15301 gccacgcata aaacgtgaca catttctaat tataaatttt gctgtttaag tattctttgt
    15361 atgcttttct ctgtcaaaaa gtatttctct gataactgct tgatactcat tccattttgg
    15421 aaatttatac agatttgaga attacgagaa gctaagactt gtttggtgtt tgtgttttca
    15481 ccccaatgct ttttgtgctc ttgctttttg ggaatataaa tcactttacc atctatatat
    15541 tcttgcactt gctcaatcag ttctttaggc agtaagtcaa tcgaattttg atagctcatt
    15601 ttgcacctcc taaataatta ctctttagga ttagcaaagg ctactgctac tcacaattaa
    15661 aaataaaatt ttttattatg tacaatagcc tttgctatgc acaagttcca attcccataa
    15721 actaaatact cctttctggt ttgaaaaatt catctgaaca ttgatttcga ttttaagata
    15781 gagttcaatg acaaatttac atttttatta tatatattca gatagataat tgcaactgtc
    15841 tttgtatgag gatattttat tatagtcaat actataatat atatttatat catcaaacta
    15901 atatgaacag ttgaaaggaa tatgaacaat aaaacttagt caggaagaat aattatgaag
    15961 cagacaattg agaaatttga ttttaaagtt ttattgaaaa tttattgaca aatttaactt
    16021 gtaaatatta tactaaactt aataaataaa gtttataaag taaggtgttg tctatgaaaa
    16081 atatagttgg aaaaccgcaa acgataaaaa aagtaaatga agatttaata aaaaacatta
    16141 taaaaaatga aggtcctata acaaaaccag aaatttcaag cattactgaa ttgagtttag
    16201 ctacagttaa taagattgtg gagcaattag ctttgaaaaa tgaagttaaa gtaagtggac
    16261 taagtgaatc tactggagga agaagagctc aattatttga aataaatgca aacttagaac
    16321 acataatagc tttatattat tatagaaatt gttgtatagg ggtagttgcc aatttattag
    16381 gtgaaataat ttatcaagaa gaatttaata taagaatgga tacatatgaa aacgttaacc
    16441 aagatacttt ttttgttata gatactctaa taaaaaagga aaaaggaaac aatataaggg
    16501 ctattggaat tggtgtccca ggagttgtaa aaaaaggtgt agttaaaaat ataccaacta
    16561 taaaaagttg ggaaggtata aatttagaaa atttaataaa gagtaagtac aatactaaag
    16621 tgtttataga aaatgataca aatattacta ctattgggat ttatcaaaaa cagtataaag
    16681 acaaatataa aaatatggct cttatgtatt tagaagatgg tattggttca ggtatagtta
    16741 taaatggtga attgtattta ggttctacaa attttgctgg agaattaagt tatctaaata
    16801 tagaatttgg taagtataac tctaacaact taaatcttga agattatatt atgagtttaa
    16861 gaaaaagata tttagaaagt aaagataata aatttaagaa agaaatttta tctataatat
    16921 caaactttat aaggactctt gtatgtgtcc taaatccaca agctatgatt atacagtgta
    16981 gtatattaac caagagtgac atggagttta tagaaaaaga tgtaagtaat aatgttggag
    17041 aagaaaattt tcctaaatta ataaaagtag agtcattgag agaaagaagt ataaatggag
    17101 taattagtat gtgtttaaaa gaaactgact atcaatattc cttatctaat aaaaaaggag
    17161 gatattaatg tgaaatattt ggtttcaata gatggagggg gaacaaaaac taaattttgt
    17221 gtaagtgact tagatggaaa catacttaaa gaacatacca ctggttcaac taattataag
    17281 tcagttggaa ttaaaaaaac atatgaaaat attaataatg gacttaaaaa aatattaaaa
    17341 gatttatata tcgattatga cgatattgag tacactgtat ttggtatatc tggttgtgat
    17401 tctcctaatg attataagat tataatggat gaaatattaa aaattgggat taacaaagaa
    17461 aaaatatatc tggcaaatga tgcagtttta gctttttatg cacaagctga ttcccctggt
    17521 ttagtaattg tggctgggac aggttcaatt atactgggaa ttaaagaaga tggagaaata
    17581 tatagagttg gtggatgggg gtataatttt agtgatttgg gttctggata tgatataggg
    17641 agaaaattat taaagaaagt attgctttat tgtgatgaat gtcatgagta tagtgattta
    17701 tttagttgtg tcttggattt ctttggagca aatagttttg aacaacttgc atatatgatt
    17761 actgatataa acaataatgt tgaaatagca aacctagctt cattagtgat tgattgtgcc
    17821 gaacaaggtg ataaattagc tattgaaata ttaagagaat catcaactga actatctaaa
    17881 ttagctcaag taatattgag aaaaatatct aatccaatga aaatagataa aagcgaaata
    17941 aatatagttt tgtctggtgg tacattaaat aaaactgtat atgctcaaat gttaatgaat
    18001 aatttaaaaa cagaaaatac agataaaaat ttaaaattta tatctcaaga aaatcagcca
    18061 gtatatgggg ggataagact tgctatggca ttagctaata ggagagttaa gcatggatag
    18121 aaaaaaggta atagtacaaa tttttactgg aggttttaag gctaaagaaa taaagtttaa
    18181 tgatataaaa tgtaaactac tagaattatt ggactgtatt gatatagaaa aggttatcat
    18241 gggatggagt gtagatgaag aattatatgt agaaactaaa aaactattaa ataaatataa
    18301 tgttgaacta tatctttggt tgccatgttt ttctgaaata ggattacttg aaaaaagtaa
    18361 tttactaatt gattatatgg ggaaggaagt caagggctat gctttacaag aggatgaaaa
    18421 ttttgaattt tattgcccaa ataataagga aaatataaaa aatataaaga aaatatatag
    18481 tacttatttt agtgatatta aatttgatgg aattttttta gataaaataa ggtatggttc
    18541 tttttcgaat aaactaaatg gtgtttttaa ttgtttttgt aaagattgtt taaatatata
    18601 tgaaaaaaat aatattgata aaaagtcgtt aatgagagaa atgaataatg tgtctaaggg
    18661 agttatagat aatgaagata ctccatctgg tataacagaa tacattaatg gaaaatacaa
    18721 atttaaaaat aaaatatggg aagatttttt tgaaacaaaa aatcaaaata tatacaagtc
    18781 attattagag ataagtagtt attttaaaag taagggattg aaaataggta tagatacttt
    18841 ttctcctttt atttcttact ttacaggtca agatttaaaa aaattacaag aagtagcaga
    18901 ttttataaaa ccaatgatgt atagaactac aaaagctcca gctggtttac catttgaatt
    18961 tgaaaggttt attgatgaat ccatacataa gaataaagag attggaaaaa gaaatttctt
    19021 agatatttta ggaattaaag agtatgaagg agatgtatat cctatagaat ttgtactaga
    19081 ggaaatcgat tttatgacaa ggaatcttaa taaagatata tatgtaggag ttgaaataaa
    19141 taaaaaggaa attatagctc ctgttacacc taagtacata agtgaaaata tttcaaatat
    19201 aaataagaca acagtaaaag gatatgtttt atcttgggat ttgttatcag caccaaaaga
    19261 aaatattgat gaaattataa aatggtttcg gaattagtga ggtgatatag tgagtaagat
    19321 attagaaatg caacaaatat ataaaagttt tggaaaggta gatgttttaa aagggataaa
    19381 ttttgagtta gaaaagggag aagtaagagc tcttttggga gctaatggag caggaaaatc
    19441 tacacttatt aaaattttag gaggagttca ttctcaaact aaaggtaaag taattttgac
    19501 tggtaatgaa ataatgttta aaaattcaca tcattctaaa gaaaatggta ttagtataat
    19561 ttatcaagaa ttaagcttga taccaacgct tacagtactt gaaaatattt ttcttggtag
    19621 agaaatttta aaaggaagtg tgtttttaaa caagaaagac atgcttgagg aatatatgaa
    19681 aatttgtgag gattttgatt ttaatataga cccacataca gtagtttcta atttaagtgt
    19741 agcaaaccaa caaatggttg agataatgaa agctgtttca tgtaattctg aaattatcat
    19801 aatggatgaa cctacaacat cacttactaa taatgaaaaa gatgggctat ttaaaataat
    19861 aagtagacta aagtctaaag gtaaaacaat agtctatatt tctcacatat tagaggaagt
    19921 ttttaaagta tgtgatagtg caagtataat gaaaaatgga attatgattg gaacttatga
    19981 tgtagaggat ttaactaaat taaagataac tcaacttatg acaggaaatg ataatcacaa
    20041 acttattgag aagaaggatt atacatttgc aaagtatgaa gagccaccag tactagaagt
    20101 aaagaatata agctggtcta acaaaataaa aaatgtttca tttaaagttt atagaggcga
    20161 agttgtaggt cttgctggtc ttgtaggttc aagaagaact gaaattataa atttgatatt
    20221 tggtatagat aataaagata gtggagacat ttttatcaat ggtaaaaaag tagacataac
    20281 ttctcctaag gttgctataa aaaacaaaat aggattgatt cctgaagata gaaaaaatct
    20341 aggattaatt ttagaacaag ctatatacac aaactcatca tcagtacaaa ttgataaatt
    20401 caagaaattt ttgtttatag atagaaataa agaaattgag ttttctaaaa aaggtgttaa
    20461 ggaattagga ataaaagtta gtgatgtaaa gcaagaagta aaagagctta gtggtggaaa
    20521 tcaacaaaaa gtagtagttt ctaagtggtt agagaaagat ttagatttaa taatatatga
    20581 tgagccgaca aagggaatag atattgctgc aaaagaagat attttcaata caatcaaaga
    20641 attttcaagt gaaggaatag gagtaatatt tatatcttct gatttagaag aagtaataag
    20701 agtaagtgat agaattttag taactagaga aggttctatt gtagatgatt taaaaaatga
    20761 gaatatacag gttcaagata taatgaacag tatatttaat gtataaaaaa tgaaaatgga
    20821 ggactgagat gaagaaagct tttgagaagt taaatttaag agattatgga gtattattag
    20881 gttttttagc tttatgtata gctataagta ttgcaactcc atcattttta ggtaaacaaa
    20941 atatacttaa tcttttacga caatcttcta taattggaat aatttcagca ggtatgactt
    21001 ttgttataat atctggaaac tttgatatat cagttggagc agtagcagct cttgcaggtg
    21061 ctataacaat gaaatttgcg actggtggaa ctaatttgtt tgcatccatg ctcttaggtg
    21121 tagcgatttg tgcagtaata ggattaatca atggtatagt agttgcaaag ataaatgtac
    21181 catcattaat agcaactatg gctatggtca ctattgtaag aggattgctg ttgatgctta
    21241 caggaggata tccaattact gaaaatatac caatacttga ttacattgga aatggatatt
    21301 tgtttaatat accaatacca gtagtaattt tctttatagt ggtgttagtt tcatttattg
    21361 tacttaataa aactaagttt ggtagatatg tttattctgt aggagggaat caagaagcaa
    21421 gtaaacttaa tggtataaat gtagattctc acaaagtgaa agtgtttatt attaatgctg
    21481 tacttgcagg aatagctgga atcgtactaa caggaagact tgggactgca actgctattg
    21541 caggtgaagg atatgatatg gatgcaattg catctgtagt aataggaggt acatcagtgg
    21601 caggaggttc tggttctgta cttaaaactg ttataggagt attacttatg agtgttataa
    21661 acaacagttt taatcttctt ggaatagatg tatatttcca gtacatattt aaaggattaa
    21721 taattttagc agcagttgga tttgattctt atagcaagaa aaaacttgct tcaagataaa
    21781 aaataagggg gattttttta tgaaaaaatt aatgaaacat ttagcattgt tgttatcact
    21841 tgttatgata tttggtttag ttggttgttc aaatggtggt gacaaagaaa aaaatggaga
    21901 aaagaaaata gcagtattac taccaggttc aacaggttac tttgtagcaa ctaaacaagg
    21961 tatagatgca aaatctaaag aattaggtgt aagcgtggaa tatgcagatg ctcaatggga
    22021 tgctagtaaa caattatcac aagctgaaga ttttatggct aaaggggtag acatgattgc
    22081 attatgtgga gttgattctg ctgtaagtga gagaatagtt aaagctgcta atgattcaga
    22141 cgtccctata gtagcattta caaattctat aggaagtaac ccaactggag aatttaaagg
    22201 tttagttaca tatataggac aaaatgagga ggaaacagga gcactaactg gaaaaattgc
    22261 taaaaactta ttaggagaaa ctggtgggaa agctgtatta atagaaggag taccaggaac
    22321 tactccacaa gtattaagaa aaaaaggtct tgaaaaagaa ttaaaagata gtaatataga
    22381 aatagtttat aatcaaactt caaattggga gaaagagcaa gctttaaaag taacagaaga
    22441 tttaattcaa aagaaaactg attttaatgt tataatatgt caagatgata attctgctac
    22501 aggtgcaggt caagctttaa aagatgctgg tcttaaggat aaagttaaag tcataggttt
    22561 gggtggaagt aaagatggat taaaagctat aactgatggg ttaatagatg gtacaactta
    22621 tatgtctgct gtagaagaag gtggattagt catagaaaag gcatctaaat tccttaaagg
    22681 tgaaaaaata gaacctgtta cacaaattaa acaagttgaa gttaacaaag ataatatttc
    22741 agagttcaag ggtgaatggt aaattgtcat agataataaa taagattttt agagttactt
    22801 tagaaactat ataaagtaac tcttttttta atttaattta gtgataaatt attgaatagt
    22861 atttctaaac aaataaaaaa ttaatataaa caaagactta attatactaa attataagta
    22921 aaactaatat aaacttatgg aaaaaaggaa aacgtctaaa gtattggaat tactatagtg
    22981 taggtgtggt attaaaaaaa cataaaaaaa cataaaaaaa ttgttgaaaa aaatatagaa
    23041 attttgtata attaaagatt tgaaaagttc ggtatacaaa gccaattctt ttgtatataa
    23101 tatatataaa ttcagaaaaa ggaagggata tgtatggcca ggcggttatt tttagaaagg
    23161 attggactta tatttttagg ttcagcaata ttagcatttg gagtttataa tttttattat
    23221 ttaaacaaca taacagaagg tggagtgtta ggtattttac tactgttaaa aaatttattc
    23281 aatatacaac cagcaatagc aaatgttgta atagatggtt tactactttt agtaggatat
    23341 aaatttttcg gtaaaaaatt ccttatatat tcaatagtag cttctataac tttttcagtg
    23401 ttatatgact tatttgaagc tataggacct ctagtaccac aatcacaaaa tatgctttta
    23461 tcaactattt tggcaggtgt aactgttgga actggtgtag gtatagtagt aaaagcaggt
    23521 tgtgcatcag gaggagacga tgctttagca ttagtaattt ctaagactac atctttgaac
    23581 atagggcaag tttatttagc aacagatgtt attgtattgt tgttatcatt attttatcta
    23641 tcagcgtttg atatctttta ttctttgatt gctgttacaa ttagtggcaa ggtaattgat
    23701 tttatttatt atcatggtaa aagtttggat atggatataa gtaatgatat agttccagaa
    23761 tgttaatata aattaaataa ctttagattt tattaggggt ggcagatttg ccaccttttt
    23821 tgtgtctaaa tctttataga aagtataatc ccatctaggt ttttgcaaat ctcaaatata
    23881 gaattatgtt ggaatgactg ggaatacgat tgctagatgt gcattttaaa aacccaattt
    23941 tatatttatg aaatactaat cattaatgga tgtttcttaa tcctatcttt atacctaaaa
    24001 tgataagata aatgaagtag caatacaaaa ctaaaatttg taaaagagat taaattaaat
    24061 ggaggagcta aaatgttgga tatagttatg atagcattgt tattcatagg atttgtttcc
    24121 atgaagttac ttgctgattg gtgtgggaaa caaactgaga aaaaataatg taatgtatgg
    24181 agggattacc tatgtggttt ctggcagttg taattataat gttaataata tatttggtat
    24241 atgcgcttat taatcctgaa aaattttaaa cagtataagg ctaataagta agttgaattg
    24301 gggggaacaa tttttatggt gcagatagta atagtgttag cgatttttat gattttagta
    24361 atacctatgg gcaagtattt atatcatata gctactaatc aaaaaacatt tggagataga
    24421 ctatttgata aagtggacaa ttttatatat aaggtatgta gtatagataa gaaaaaagaa
    24481 atgaactgga aacagtatgc attagcttta ttatttacaa atgcagttat ggtatttata
    24541 ggatatatca tacttagaac tcaaagtatg catattttta atccaagtgg aattaaaagt
    24601 atggaacaag gactatcatt taatacaata ataagtttta tgacaaatac aaatcttcaa
    24661 cattattcag gtgaatcagg actttcatac tttagtcaga tgacagtgat aatatatatg
    24721 atgtttacat cagcagcaac aggatatgcg gctgctatgg catttgtaag aggtctagtc
    24781 ggtaaaaaga aaacattggg aaatttttat gtagatttaa ttaggataac aacaagagta
    24841 cttttaccag gagctttaat tattgggctt atattagtta cacaaggagt accacaaact
    24901 tttgctggga cagaaacagt gactactata gaaggaaagc ttcaagatat agctagaggt
    24961 cctgtggcag ctcttgaatc aataaaacat ttaggaacaa atggtggtgg attctttggt
    25021 tcaaattcat cacacccatt tgaaaatcca acaataatat caaatatagt agaaatatta
    25081 tctatgatga tattaccagg agcttgtgtt gttgcattcg gtcacatgat aaagaataaa
    25141 aaacaaggtt gggttgtgtt tggcgcaatg tcaatcatat ttttaatagg tctagtagtg
    25201 tgctttaaag cagaaagtgc aggaaaccct attttatcac aattagggct taatcaaagt
    25261 atgggaagta tggaaggtaa ggaagttaga tttggtatag cacaatcatc attattcaca
    25321 acagtgacta cttcctttac gacaggtaca gttaataata tgcatgatac actgactcct
    25381 ttaggaggat tagtaccact tttaaatatg atgctaaatg tagtatttgg tggtaaaggc
    25441 gtaggtctga tgaatatgtt gatgtacgct ataatagcag tattcttatg tggattaatg
    25501 gtaggaagaa caccagagtt tttaactaag aaaatcgaag gaaaagaaat gaagcttatt
    25561 gctttactta ttatattaca tccactttta atactaatgt tctctggtct ttcagtagca
    25621 ataccagcag ggcttgaagg aatttcaaat cctggattcc atggattatc acaggtattg
    25681 tatgagtttg catcttcagc agccaataat ggttcaggat ttgaaggtct aggagataac
    25741 actatgtttt ggaatataac aacaggtata gttatgttct ttggaagata tgtgtctatt
    25801 atagtactac tagcaatatc aagtttgtta gcatctaaaa aagctgtaaa tgaaagtata
    25861 ggaacactta gaacggataa ttttacattt acaatagttt tagtacttgt tgttttaatt
    25921 gttggtgctt taacattttt cccagcctta gcgcttggac ctatttcgga gcatctagtg
    25981 ttgtggcact aaaaaattgg gagggagtaa agttttatgg aaactaaaaa aacaaagttt
    26041 attacaaaag atattttcaa aacttccatt atagaagctt ttaaaaaatt aaatcctaaa
    26101 tatatgatga aaaatccagt tatgtttgtt gtagaaattg gatttatagt aacattgata
    26161 cttacaatag tacctagttt gtttggtgat gaaggcaata atttaagagc ttataatggg
    26221 attgtaacaa taatcttatt tataacagtc ctttttgcaa attttgctga agctgtagct
    26281 gagggaagag gtaaagctca agcagataca cttaagaaaa ctagaaaaga tacagtagca
    26341 agggttatag atacgttagg aaatgaaaaa atgataagtg caagtgagct aaaacttggt
    26401 gatattgttt tagtaaatgt tggagaagtt atcccaaatg atggagaagt tatagagggc
    26461 atagcttctg tggatgagtc agcaataact ggagaatctg cacctgtcat gagagaatca
    26521 ggtggagatt tcgcatctgt tacaggtggt actacagttg taagtgactg gttaaagata
    26581 agaataacaa caaaaccagg agaatcgttc ttagataaaa tgatagctct tgtagaaggt
    26641 gcttcaagac aaaaaacgcc aaatgagatt gctttaaata ctttgttagt agggttaaca
    26701 cttatattta tggttgtttt aatatctctt tatccaatgg caaactatgc aggtgtaaag
    26761 attccaattt ctactatgat agctcttttg gtatgtttaa taccaactac tataggtgga
    26821 ttgttgtcag ctattggtat tgcaggtatg gatagagtaa ctagatttaa tgtaattgca
    26881 atgtcaggaa aagcagtaga agcttgtgga gacgttgata ctatgatttt ggataagaca
    26941 ggtacgatta cttatgggaa tagacttgca tcagaattta tagcagttgg aaatgcagat
    27001 tcaaaagatt taataaatta ttctgttatg tgttcattaa aagatgatac accagaagga
    27061 aaatctatag ttgatttagg tatgaaatta ggttcaacag gtaagacaaa agaggcagag
    27121 gaagctgagt ttgtagaatt ttctgcacaa actagaatga gtggtattaa cttagctgat
    27181 ggtagagcta taagaaaagg tgcttatgat agcataataa aaagagtaaa agaatctggt
    27241 ggtacagtgc cagaagattt agaagaaaat gtaaatcgag tagctaaact aggaggaaca
    27301 cctttagtag tgtgtgtaga taatgagata tatggaatta tctacttaaa agatacagta
    27361 aaatcagggc ttgtagaaag atttgctaga cttcgagaga taggaataaa gacaataatg
    27421 tgtacagggg ataatccctt gacagcagct acaattgcaa gagaagctgg agtagatgga
    27481 tttattgcag aatgtaaacc agaagataaa atagatgcta taaaaaaaga acaattagag
    27541 ggtaaaatag ttgcaatgac aggtgatgga acaaatgatg ctcctgcact tgctcaggca
    27601 gatgtaggtc ttgcaatgaa tagtggtaca acatctgcaa aagaagcagc aaatatggtg
    27661 gatttagatt cagacccaac taagatattg gaagttgttg aaataggaaa acagctttta
    27721 ataactcgtg gggctttgac aacatttagt atagcaaatg atgttgcaaa atattttgcg
    27781 attataccgg ctatatttac tcttgcaata cctcaaatgg agatattaaa tgtaatgaaa
    27841 ctttctacat catttagtgc gatattatca gctttaatat ttaatgctat aattatccca
    27901 tgtttaatac ctcttgcaat gaagggagta aaatatagac ctatgaaatc acaagctatg
    27961 ttaatgagaa atatgcttat atttggtctt ggtggagtta tagtaccatt tttaggaata
    28021 aaattaattg atttattgat tacaccttta gtaatgattc ttaatttagg ttaataaatg
    28081 gaggatataa aaatgaaaac attaaagcca gcattacttg taagtattgt attgttagtt
    28141 gtttgtggac ttgtatatcc acttgttttg acaggtgtaa gccaagttgc atttaaagat
    28201 aaagccaatg gaagtatgat agaagtaaat ggtgtaaaag taggttcaga acttattggt
    28261 caaagcttta cagatgcgag attctttaag ggaagagtat catcagtaaa ctataatact
    28321 tatacaaaag aagatttagt accagataaa gatggaaatg catcttatgg aggtgtatca
    28381 tcagggtctt ttaattatgg agctacaaat ccagaacttc atgatagagt acaaaaagat
    28441 atagaaaagt ttttaaagga taatccaact gtcaaaagag aggatatacc aacagattta
    28501 cttacagcat caggttcagg acttgaccct aatataagtc cagcctctgc aaaaattcag
    28561 ataccagcta tagcaaaagc gtctggaata tcagaaagta aattacaaaa aattgtagat
    28621 gataatactt ccaaaaaact ttttggagtt ttaggtgaag atagagttaa tgtactaaag
    28681 gttaatatag aggtcgcaaa aatattaggt cttatatagt attttgtgga attttagtaa
    28741 caaaatatta ctcaagattt aatttaaagg ttaaatttta aagagtgaaa atcaataatg
    28801 attttcactt ttttatttga atattactaa tatttggaat aaagtgattg taagtataaa
    28861 atccaaaaaa aggttgcatt atcaaaatga taatactata atatatttat cgttatcaat
    28921 ttgataatag atttggacat ataggaggaa atagtatgtt atataataac gcattagagt
    28981 tgataggaaa cacacctgta gtaaggctga ataatttagg ctgtactaat gggtgttcta
    29041 acatatatgt aaaattagaa aaagtaaatc cagcaggaag tataaaagat agagctgttt
    29101 atgaaatgtt agagggctta gagcaaagag gagaattaaa aaagggagat gtactagttg
    29161 aagcaactag tggaaatact ggtattgcat tatctatgat aggaaaatta aaaggatatg
    29221 aagtagtaat cgtaatgccc gaaacaatga gcgttgagag aagagattta atgaaggctt
    29281 atggagcaaa tttggtgctt acagatggta aagctggaat ggcaggttcc atagaaaaag
    29341 caaatgaact tttaaaagaa aatccaaact ataaaagctt aaaacaattt gaaaataaag
    29401 ataatccaaa tgcacattat aaaacaacag cagttgaaat tatgaatgat gtcaaagatt
    29461 tagatatatt cgtatgtgga gttggaacag gtggtacttt aataggaact gcaagatatt
    29521 taaaagaaca aaatccaaac ataagagtaa ttgcacttga accaaaaaaa tctccagcta
    29581 tatcagaaaa caagactgga cctcataaaa tacaaggaat aggtgctaac tttgttcctg
    29641 aaaattatga ttctagtgta gttgatgaag taatattagt agatgatgaa gatgcatttg
    29701 atacagttaa attacttgca gcaaaagagg gaattttagt agggatatct tctggagcaa
    29761 atatatttgg tgctatagag atggcaaaaa agtatccaga taaaaagata gttacagtag
    29821 ctccagatgg agttgataag tatatgtcta tgggaatatt ttaataattt tatttgaggg
    29881 agtgaatact ttgtttaaga aaataaataa agatattgaa tatataatga agaatgatcc
    29941 agcagctagg tctaagatag aagttttttt actttatcca tcagttcatg caatgataat
    30001 gcataggatg gctcatgctc tttataagaa gaagaagctt tttacagcaa gattaatatc
    30061 ccagatatcc agatttatga ctggcataga aattcatcct ggtgctaaaa tgggggaagg
    30121 tatattgata gaccatggaa tgggtgttgt aattggagag acagctgaag taggtaatag
    30181 ggtgacaata tatcaaggag ctactttagg agctacagga aaagatactg gaaagagaca
    30241 tccaactgtt ggtgatgatg tattaattgg tgctggaaca aaaatactag gacctttaaa
    30301 tataggttca aattcaaaaa ttggtgcaaa ttctgttgtc gttaaggatg tacctaatgg
    30361 tgcaacagtt gttggtatac cagcaaaaat agtaaaaata agaaacctag aacctgtaaa
    30421 aaagaataaa aaagaagtgt cctatgagta tgatgaatta gataatgtat attatatata
    30481 ggatttatat aactataaaa taaactttat aaaaattatt ttaaaaggta tttttttcaa
    30541 atttgaggac ataataaaaa agaactgaat gttacagttt tggttcatca atctttgata
    30601 aacaagattt taaatttgta gcgtctagga ggattttatt atgaaagcaa atgttaatca
    30661 agatacttgt ataggttgtg gattatgtcc atcaatatgt ccagaagtat ttgatatgaa
    30721 ggatgatggg aaatcacatg ttatagttga tgaagtacca agtgatgctg aagaatcagc
    30781 agcagaagct agagaaagct gtccagttga tgcaatagat gtgcattaat aaaataaatg
    30841 cctataaaaa ttgaattttc aatttttata ggcatttgtc ttttattcag ttagtatttc
    30901 aacccctgtt tctgtaacta aaaccataca ttcccattga gcagataatt taccatcttt
    30961 tgtataaata gtccaattat tttcttcatc aacaaaaatt tcgtgagttc cttcatttac
    31021 cataggttct attgtgaata tcatcccagg aaccaatagc atctcagtcc cttttttaga
    31081 tacataactt acaaaagggt cttcatgaaa gcttaatcca actccatgac cacctatttc
    31141 tctaacaaca gagtatccat ttttctttgc ataagagttg atagcatcac ctatatctcc
    31201 taaaaatccc catggtttgg caacttcaag acctttttgg acacattcct ttgtaacttg
    31261 aactaatttt tttgcatttt cattaacatt acctatcata aacattcttg aagcatctga
    31321 atagtatcca ttaaaaatag tagaaacatc tacatttata atatctccat cttttaagat
    31381 aatgtccttg cttggaatac catgacaaac ttcattattt actgatgtac atacactttt
    31441 aggaaatcca ttatagtcta gtggagcagg gatagctcca ttttgtagtg taaagtcatg
    31501 aaccaactta ttcatatctt ctgtagacat tccaatttcg attttatctg aaatataatc
    31561 caaaattttt gtgtttatta cagcactttt ttttatttcc tcaatttgac tttcattttt
    31621 tataatatca tgagttggta caatatgacc taacttagca aatgaatcta ttttattatc
    31681 catatccata tgacattttt tatatttttt agtacttcca caccaacagc tatcatttct
    31741 atttaacttc ataacttttc atccttcttt tattatttat ttaaattatg ggttacataa
    31801 actattttaa aacataacca ttataaatat tataacataa atactaagaa atcctttata
    31861 gatagtgatt tattcaaagt ataaattatt atatggttat tgttgatgaa aagaggatag
    31921 ttaaatgtat tattggatat tagcgcactt aatagtttag ttcaagtttt tcaagaaaat
    31981 catatgttag aggacaattt tcctttaaag tattttttga atcttcatca agataataat
    32041 gcacaaatga ttctgcaaaa aattcttcta taaacttgct tatatatgca tgtgcaactt
    32101 gtttagggtc ataaagctta tatctttcct gagcaaatac ttccataaat tcttcagaat
    32161 ttgatttttt atttaaaaca tttttatcta tagcatgtgc agtttcatgt aattctaaat
    32221 tttttgatga atgtacattt gcatagctag ggttactata acctatttta gctactatag
    32281 aattatttct atatatacca ggtacatctt tccaagtctt gcctgatctt acccaacatg
    32341 gaggtaattg atattttaaa tcactaaatt ctggttcatc agttagattt gaatttatta
    32401 attttatttt tatatccttt tctttaagtg tctgtaaata tttaatattt atttttgcaa
    32461 gtctgctttt catattttca acttcatctt tatcataatt caagtcatca ggaagtataa
    32521 gcatttgttc aattatatct atgctactgt cttttatatc ttcagattct tcatcaaatt
    32581 tatattgaag agtattattt tcatagatag ttatatttgt attattttcc atataataag
    32641 agtgaatatc ctctaagtct aaaatattca tttgttgtaa aatatgtttt gtttcgccac
    32701 tccatactac taaagaaagt gaattaaaat taattagtgg attttccttt gcttttatat
    32761 cattgcttat atctacatca aatacatatt caattgagtc ttctatgtta agactatctg
    32821 tattcttttt aatatataaa tatgcttgtt ttaagtctat ataaatctca tctaaagatt
    32881 catcataaaa ttctgataaa ttattagtaa agagttcttc acttaaaagt tcatttttat
    32941 cagttatact ttcaattaaa atattaattt cttttatcat atcgtaaata cttatttttc
    33001 tatttgcttt ttcactagat acattgcatg gcgcaagagc aatgcaataa aaatcttttt
    33061 cttttttata aaaggcttta agtgattttg ataaaagtgt aaagtctaca cctatctgta
    33121 agttgacctt aagtgagtca ttttgtaata attcagtatt atttttttta gctatattta
    33181 aattgttttc cataatcatt gccccctttt tattagggta tcataatttt tttatatgtg
    33241 tcaatttgtt tttttgaaaa ttataatttt tttgaaaatt ttatttttta taatttgtga
    33301 attttttatt atagaaataa atatgttatt attatgtcaa aatttagcat tagattcatg
    33361 tagagtatgt tttatacata tattataatt aattctttga agattgcata ttcaaaatac
    33421 acaccatttt ttttaattct ataatataat atttatatat ttaatgttag gatgtgattt
    33481 aaggtgtatt ttacatatat tataagatgt aaagatgatt ctctatacac tggatatacc
    33541 agtaatatag ttagaagaat gaatgaacat aagttaggaa ttaattcaaa atacacaaga
    33601 gcaaagggat ttgaaaaact agaagtttat tttgtgacca acacaaaaag caatgctatg
    33661 aagttagaat actatataaa aaaattaact agaaataaaa aattgtctat aataaaaaac
    33721 ccaagtatac ttataaattt aattgataat aaagaagatt atattattgg taaggaaata
    33781 gaacaattaa cataaatatt tatagtaaca ttataatggg tgcatatagt gtaaaaactt
    33841 gacaataaat actattgtaa tataatgaag ttataaatat agtaaattaa aatagctagg
    33901 ggagccaaga gctgagaggt ataccgaccc ttacacctga tctggataat accagcgtag
    33961 gaaagcttag taaaaattca agtatgtatt atttgtgata tatgctattt ctaagctata
    34021 cctattgtag gtatagcttt tttaattaag ttatttaaat taaactttag gaggcaacaa
    34081 tgagtaatta taaaatacca acacttacaa tagctggctc tgattcatct ggaggagctg
    34141 ggattcaggc tgatttgaaa acgtttagtg caattggtac ttatggtatg agtgtaataa
    34201 cagctataac agcacagaat actaaaggag tttttgctgt agaggattta aataagaaaa
    34261 taataaaaaa acaaatagag gcagtctttg aagatatacc tccaagagct gtaaaaatag
    34321 gaatggtttc aagtcctgag attatacttg aaatagttga gaatctaaag aaatacaatc
    34381 caaaatattt ggttgtggac ccagtaatga tatctaaaag tggatattat ctattaaagc
    34441 cagaggcaaa agaaaactta attaagtatt tgataccact tgcatacata attacaccaa
    34501 atataccaga ggcagaagaa ataacaggaa taaaaataca taatgtagat gatatgaaga
    34561 gagtaggaga agaaatacta caacttggac ctaaatttgt acttatgaaa ggaggtcatt
    34621 tagatggaga agcagtggat attttagttg gtaaaaatat atttaaagtt tataaaagtg
    34681 aaagaattga taaaaaaaat acacatggaa cagggtgcac attatcttct gcaataacat
    34741 cttatctagc attaggatat gaaataacag aagcagtaaa tctaagtaaa atctatataa
    34801 cagaagcaat aaaaagaagt tttgatatag gtcatggagt aggaccagta catcattttt
    34861 ataaatttga gtaataaaaa aatattggag gtagaatatg tataatttaa ttaaagatgt
    34921 aaaaaaatta aatccattgg taattcatta tactaataat gtaactataa atgattgtgc
    34981 taatgtgact ttagctgtag gagcaagtcc tcttatgagt ttttcatatg aggaagtaga
    35041 agaaatggta agtgtagcaa attctgtagt aataaatata ggaactatga actcaaatat
    35101 gttggattta tttctattag ctggaaaagc agcaaataag tacaataaac ctgttgtttt
    35161 ggacccagtt ggagtatttg caagcaaagc gagagcagaa cttacaagta gacttttaaa
    35221 tgaagtcaaa tttagtgttg ttaaagggaa tgtatcagaa ataaagttta taggtggctt
    35281 taatgtaagg ggtaaaggtg tagattcatt tgatgaagaa gaagattcta ctgagataat
    35341 aagaaagatt gctgaaaagc ttgaatgtgt agttgtagca actggaaaaa tagatataat
    35401 aactaatggt aaaggtatat ataaaataaa caatggaact gataaattaa aaggaattac
    35461 aggaactgga tgtatgactg ctagtttgat tgcaagtttt atggctgtta ctgagaatat
    35521 attagaagca gcaacaatgg gtgttcttac aatgtcttta agtggggaat tagctaattt
    35581 aaataatcca ccaataggta catttaaaga aaatcttatg aatgctattt atcaaatgga
    35641 tatagatact ttaagtaaaa attctaatat tgaattttta aattaataaa gagtaaggga
    35701 gacttaaaat gattgataaa gaatctttaa aaaaatgctt aaagttgtat ttggtaactg
    35761 actctgaaat gcttaaaggt agagactttt ataaatgtct tgaagatgca atatcttctg
    35821 gaataacaac tgtacaactt agagaaaaaa atgcttctgg aagagagttt ttaagaaaag
    35881 ctatgaaact tagagaaata actgaaagat atggtgttaa gtttataata aatgatagag
    35941 tggatatagc acttatttgt gatgcagatg gagtacatgt aggacagagt gacattgatg
    36001 tgagagaggt tagaaagctt ataggaaaca ataaaattct aggagtatca gcaagaactt
    36061 tagaagaagc tacttgtgca aaaaatgatg gcgcagacta tttaggtgta gggtctatat
    36121 tcacaacatc tactaaatta gatgcaaaat cagcttcgtt tgaaactgtt aaagaaatta
    36181 aagaaaaagt agacatgcca tttgtgctaa ttggaggtat aaatttagac aatatagata
    36241 aacttaaatg tttagaaagt gacgggtatg ctataatatc agctatatta aaagctgaag
    36301 atatctctaa agaagtggaa aagtggacat taaaaatata aaattggctc tggtagtgaa
    36361 aaaaatggaa aaatttgata taatctaaga gtaaaattta agcaattata aatgataaac
    36421 ttttctacat atacttttta atcaagatat atgtagattt ggttaaaaag gagctataaa
    36481 tgattaagat attgttagtg tgtgttggag gcatgtcttc taccctattg gtaaataaaa
    36541 tggagaagga tgcaaaaaaa agaaatatag actgtaaaat atgggcagtt ggagaaggag
    36601 atataaaatc ggagcttgat aactttgata ttttacttct tggaccacaa cttagattta
    36661 tgcttgatga cgtaaagtct atagttggag atagagttcc agtatctata atagatatgg
    36721 taaactatgg tacttgtaat ggtcatgctg tgttaaattc ggttttagaa atattaaaat
    36781 aaataataaa agtggattct atataataga gtccattttt attatttgtt attaataggc
    36841 ttaaaactta gcttaccatt tcttttttta atctccacat agcaagtgaa aaacttgaac
    36901 agcacaatat taaaaatagt aggataacag gcagtatatc tccaataaga atagtctcac
    36961 caaatattaa gctacgtaaa gcgttaataa catgggtaaa tggattgagc atcactgcta
    37021 cttttaatcc tccagataaa ctttctatag ggaaaagagc tgaacttaaa aagaaaatag
    37081 gaagtacaat tgcagtcata attgtttcat aaactatttc atttggcaat aataaactta
    37141 tagaataagc tagacttgat aaaaagaagg ctgtcataaa tatcagtact atcataagta
    37201 ggattccacc aatgccagat tctatcctta ctgagaagaa tatacttact atacacaaaa
    37261 tagttacttc tatgaaggaa actaagatag cttctaataa ttgaccaagg acgattgaat
    37321 acctactgat aggtgcaatt aagactctat agaaacttcc actgttcttc attataaagt
    37381 ttataatacc accactacta caagaagaaa acacaaccag tacaatgata cctggtagta
    37441 taaaagcagt ataattattg atatttatat tattcatagt ttggtttgca atagaactat
    37501 aaagcacaag ccaaagaaaa ggttgtaata tagtaactac aaatgagatt ggatttttaa
    37561 aacgccactt catactacgc cataagatat ttaacattcc cattcctcct ttaagctttt
    37621 tttagaactt gtaagtgcta aaaatacatc ttcgagactt ggctctacaa tttctattgc
    37681 atcaaattct atatcatgtt ctaaaagcca tttatttatt aaagtaaaag cagttctact
    37741 atcgtttaca cttataaaaa ttgaattttc tcgtacgctc ataaacttta ctaaaccagt
    37801 acttttaatt gaatctttat atttttttat atcttcagta ttatggaaag ttatacgtag
    37861 tatattttgt ctaatgtaac tacgtaaact tgatggtgtt ccttgtgcta aatcctttcc
    37921 attcttcata atacaaatat tatcactcaa ttgttcagct tcttcaagat aatgagtagt
    37981 tagaaatata gttgtgccgt actcatctct aatttttaat aacatatccc acatagattt
    38041 tcttgaatcg acatccatac caacagttgg ttcatctaaa aataggattt taggagatga
    38101 taccatattc atagctatgt ccaatctacg ttttacaccc cctgaatatg atgaagtagg
    38161 atattttaag taactagata agtcaaactt atcaattaaa gagtctattc tttgttttgc
    38221 aatctgtggt tctactttat acattttact ttgaaatacc atattttcca taagggataa
    38281 atgttcatca atagagattt gctgtgctac acaagcaatt tgagtacgta tccaagaagg
    38341 attatctact aaatcttttc caaacatttt tacatttcca gatgtaggtt tgtaaaaggt
    38401 agtcaaaata tttataagag aagatttacc agcaccatta ggaccaagta aagaaaaaat
    38461 ttctccagca tttacattaa agcttagacc atttaaagct ttcacaccat ttttatattc
    38521 ttttactaaa ttgtctattt caatcgctaa catatattat tcctcctctt taagtggaaa
    38581 tattatctct gtaatatagt tatctgggtt tccttttatc aacatacctg gtcctttaat
    38641 aaatacttct ctccaaggag tttgtatttt tatattattt tcatgaatat atttaaatat
    38701 catttcatac gtttttggca aattactata agagcctgtg tgagtaaaaa ataaagcttt
    38761 tgttttagga aattcttttg tagttatacc catacgattt ggagtttcag cagttggaac
    38821 acataattcc atttctgcaa caccagtttt ttggtcaaca tcatagtagc aaaagaatgg
    38881 tgcaccgtta gactttcctt ttatagcttt aaatacattt ggaaaatact ttgttgcctc
    38941 agtcataggt ccattataac gcatggtagc cactgtgact gattcgatat ttttgatttc
    39001 aattttgcaa ttcatttgtt tacctcctaa tgtgtgttca tattcttact agatttttaa
    39061 gcattaatac atataagatt ttgattagtt gaaaacatat aatcttatct cgtttgcttg
    39121 ttttcaagtc taacataaca taaaatatat atcctctcat ttgatgctcc attttgtaaa
    39181 gctattattt aagctttact ttagattttt tagcaaattg aaataaagca atttataaaa
    39241 taagtattta caaattaagt gtattaatcg tataatacac ttaataggat actagataaa
    39301 gtctgaaata aaggcgtatt tttttaaagt aagtgtacta tcgtattaat acactagaat
    39361 aggaggaatc atgaattttg aattagataa tacaactccc atttatttgc aaatagtaaa
    39421 gtatataaag agacaaatag taacaggaga gttgaaacca ggagagacaa taccatcaag
    39481 aagagaaatg gcacttaatc taaaagtaaa cttaaataca gttcaaagag catataagga
    39541 gatgggtgat atgaatataa taaatacttt taaaaattat caaagcagtg taacagttga
    39601 tgaaaatata ttaaaaaatt taaaattaga gcttataaat gaatcactat ctgtttttat
    39661 agaagatatg aaagcaataa atgttagcaa agaagaagtt ttaaaaataa tagaagataa
    39721 gtattagttt tttaacaaat agaaaactta gtttagaaag tttatttata agcatattgg
    39781 atgtggagga tagtaaatat gatagaaata aagaatgtca gcaaaacata taaaaggatg
    39841 caagggctta aaataagaaa gatagaagct ttaaaaaatg taagttttaa tatagaaaag
    39901 ggaaaaataa ctgcattact tggtataaat ggtgttggta aatcaactat gttaaaagca
    39961 atagcaggac ttataaacat tgatagtgga gaaattcgta tagatggaga aaaaataaat
    40021 gaaaaggtat acaataaatt ggcttttgtt ccagatgtac aatctcactt tagcaataca
    40081 acaataaaag aaacatttga atttatggaa attttttatt caaagtggaa taaagaaaaa
    40141 tcaaaagaaa tgatggacat atttaaattg gatgaagatg aaataattga taacttgtca
    40201 aaaggaaaca ttgcaagagt aaaattaata cttggatttt gccaagaccc agagtacata
    40261 cttcttgatg aaccatttac aggaattgat ttgtttaaga gggaagagtt tataggagta
    40321 atagcgcaat atatggagga aaatcaagcc attatcataa ctactcatga gatagtagag
    40381 atagaaagtt tagttgatga ggttgtaatt cttgatgaag ggcagattat aacttcattt
    40441 aatgcagaag aattaagaga aagagaaggt aaatctatat tagataagat gagggaggta
    40501 tataagaatg aataaacttc tatatctaat aaatgtagat ttgagaagaa gcaataagtt
    40561 ttatatagct tatatatcat ttttttcatt aattacactt agtttaaatt tattcgaaat
    40621 taataaattt aaaaattcta aatttattat gaacttagca atagaagatt ttggaggtat
    40681 attttatgga ctagggatac ttagtaatct tggttttatc caaaatatat tgttctttgg
    40741 aatgttggga ctttttatat actatatttt tatgtggaaa agagagttct tttcaaataa
    40801 tcaaagtatt tatacactta tgatgttacc tcaaaataag tttaagattt gtatatctaa
    40861 atcaatagtt ttgataacaa tgatatatgg ttttttgata agtcagacag caacattatt
    40921 tatatgtaaa tatatattta atttcatttt tagaaatatt cctataatca atatgaactt
    40981 tgccaaagat ttatattatt taaacttgaa gagtatacca attgatttta tctcttttat
    41041 ggctatttat gtatttttac tacttatagc tatttctatt gtaaattgct gtatattatt
    41101 tatcttttcc tatataaata aattttatgt aattttaatc actttgctga ttatagcagg
    41161 cttatatttt tcaacaatat atataaatat aatcaattta tttagaaaat attataatct
    41221 tataggattt caatttaaca atttagtagc agggttatta agttttttaa ttataatgtt
    41281 tattctaaat ggaatatctt atttgctaat taaaaagaaa gtatctcttt aaggaggggt
    41341 ggtatgaaat taaaatctaa aatatctata cttattatat ttttgacttt agcaatatat
    41401 tttagtatag gtttattaaa taatgaagat aatttaaaga taaaaactat aaaaggtgac
    41461 tctaatgaat tagaccatat aaacataaat tttggatatg ctttgaatgg atatataaat
    41521 tcatattata caataaatgg aagtaacaaa actaaaaaga ctgaattaat aaaactacaa
    41581 aaggatagta agaacacaaa taatttaatt gatgtatcta gtggttcaga tttaattgct
    41641 catgttggat ttgaaatgaa tgaggagtca aaagatataa actttgtgat agatgagaaa
    41701 aaagaagatt tagaaaaagg tgtatttcca tcagaaggta gtgataaaga aattgaatat
    41761 gaaaaattag atatgaataa ttttacaagg acaagatata aagtagataa aagtacagat
    41821 gattattatg caaatatact agcatcaaaa agatataaaa aatacttata tgtatctgta
    41881 ctttatgcta caagtgattc atcagaaaat aacaaagaat attcaagtac tatagatata
    41941 ataaaaatta atccagaaaa taaaaaaatc aagactataa aaagtataaa tttaagtaat
    42001 tatttttccg agaaatacca agacatagag aacataggtg taagttatgc tagcaaatat
    42061 gaggataaga tgtatatttt agtaaatgta ctaaatacaa acataggtga taatagtaat
    42121 tctaaatttc atttacttga gtataatctt gaagaaaata aggaaagcat aatggaatta
    42181 aaaactgata gcaaaatggc tttagcaaaa gcaaagttag aagctaataa attatatatg
    42241 gtaatgtcga atgattatga taatagttca attacagagt taaatttact tacctataat
    42301 atattagata aaagcttaga tgaagataaa tatgttttag ataatagaga aaaaagagga
    42361 attagaagta ttgaaattga ttcaaataaa atcgttgcat atacatcaag gctaaactct
    42421 atattatctt gggataataa atttatgcta tatataataa ataaaaattc taaggaaatt
    42481 gtatatgaag gagaattaca atttaacagt tcaaatagta tgttagaatt tgaaataaag
    42541 taggtgagtt gatgaaagat ttaataagat tattcgaatt tgaattaaaa agaaatataa
    42601 agaattatat atttataata atttgttgtt gttcttttgt aattttaaac atagtaaaaa
    42661 atttaaatga ctataattac ataatagaaa atgcagttaa aagtgaacag ttaacaaaaa
    42721 tcggaaatac gatagaaacg gtaaatgtta caggtttctc aagctttaga aatataatgg
    42781 gttctacaga atcgtggttt atatttggta taattgcatg tatttgctat gcttttttta
    42841 tttggtatag agactttaat ggtaggagta aatctatata tacacttata atgctaccta
    42901 aaaatagaat caatatttat atatctaaat tattaaatat attatttcta gtgtatagct
    42961 atacagtagt acttacaata tctttgttta ttgcaagtaa gttgttgcct agacatatgc
    43021 ttggtaatgt cacaaactat ggttttgtac aagaaacaat atatgagtta aaaatgttac
    43081 ttccatatag ctttgaaata ctatttgtag agtatatatt tttattgata ggatttgtat
    43141 ctgtagtatt tacatcaatt cttataaata aatctattta taaagtaagc actttaataa
    43201 gttttctatt tttagttttg gaaattttag tgtttataat ttctatagaa tttattatac
    43261 cttatgaata cagtgatgta tttactgttc tatattcaag tataaacata tttgtatgta
    43321 gtcttatatc taataaactt ttgaagcaaa agattgactt ttaggaggga tattatgaaa
    43381 gcaaaaaata taggaaaata tacaatatgt tttataatag tatgtttttt aatgattact
    43441 atgaccttaa tattgagtta ttttaataag gataaactat ctgtaaaaac tttaaaaggc
    43501 aatgtaaaag atatagggag agtaagtgta gtatatacac ctaatataag caaattttct
    43561 tatgaggagg taattataag taaaaatgga gtaagaaata ataaaaaccc caaatcaaga
    43621 attagaaatg attatttaaa tattgacaaa aaatacagtg attttgttaa tgataaagga
    43681 aaagaactta tatataaaga tgatttgaat ataggagaag cgtatacctc tgttaagtct
    43741 gatttagtac aaggaatgaa tgctttaaat gattgtataa aggtttcaaa taaaaattta
    43801 aaaagtgggg tagaagaaaa ttttgatatt aatttaaata agtctgattt taaagaaaac
    43861 agttggaaaa ccttgtttaa taaaatatat aaaggcaatt tatatatggt aattagtgaa
    43921 actaatattt caggttctaa ggtcaataat atttgtatat taaagataga tataaaaaat
    43981 aagtcttata aattattaaa tagatttaat ttaggattac agaatggata tcaacaaaat
    44041 atcaatgaaa ttaaattttc tattggaagt aaattatact tagaaatagt aaataataaa
    44101 agtaaaaatg gagatattga aggacatgat agttactcta accttattat atatgatata
    44161 gaagataaca cttttaatat aagtaataaa tttatggata atctaaacaa agaaaagaat
    44221 gcaaatccaa aggagattgg cttattaagt aaaactaagc tagattatat gataaaaaat
    44281 aataaattga atcttatagt tacggatatg agtaattcca taatcaatct tgtttatgat
    44341 attaattcta atgagattaa attagaagat tatgagatac ttgatttaaa agtagattat
    44401 aatgaagcat catctggagt taggaaagtt aagttactgg atgataagat ttattctatt
    44461 tcaggtatga agaacagtat atcaggagaa ttaaaaggat ttaaagggat tgttgatgta
    44521 gtcggaacta agccagtaaa atttcaagta tttgatatga aacttaaaaa gaatatttat
    44581 gaagctgagc taataaatgg agatataagt ttacaagaaa agttattttt tgttgcaaat
    44641 taagtattag aattaatttt agaactttaa acttttatat gtatcacaga taagtataag
    44701 taagggagtg tctcaaaata aactttttag ttcatgagac acttttttta tatgaaatca
    44761 aatatatttt cattgtttag atttattttg ataatgaaaa aaagattat
//
LOCUS       DAMJWO010000027        44337 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.028, whole genome shotgun sequence.
ACCESSION   DAMJWO010000027 DAMJWO010000000
VERSION     DAMJWO010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44337
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.028"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..433)
                     /locus_tag="PC366_001504"
     CDS             complement(<1..433)
                     /locus_tag="PC366_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HDF2577035.1"
                     /translation="MKNLNLLINKLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMIDNENSYIRTRGLLLISANAQWDIDNKIEINIDSILSHIVDKKPSVSRMFIKSIPN
                     ITKYKENLINRIKMELSNADISIYNNNMKPLVEKDINDTLSN"
     gene            complement(639..1016)
                     /locus_tag="PC366_001505"
     CDS             complement(639..1016)
                     /locus_tag="PC366_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HDF2577036.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTKAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
     gene            complement(1132..1626)
                     /locus_tag="PC366_001506"
     CDS             complement(1132..1626)
                     /locus_tag="PC366_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDF2577037.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDGFIVSVYIGDEKFNNLKNECIKK
                     GIDIKISKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKNIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            complement(1775..6028)
                     /locus_tag="PC366_001507"
     CDS             complement(1775..6028)
                     /locus_tag="PC366_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HDF2577038.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYEKLGDINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGANQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEDNIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKISYVDINSIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINEVYDILPKNIKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKEELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEVNHAVDKATDEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANVQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMFERESKNIDVKNIKVNRIQYAKNNQITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAIYDAGFKDVPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKSSLVKAKISVFT
                     RNIKDIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEAFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            complement(6409..7578)
                     /locus_tag="PC366_001508"
     CDS             complement(6409..7578)
                     /locus_tag="PC366_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577039.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYNPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGQEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLVG"
     gene            complement(7973..8989)
                     /gene="gap"
                     /locus_tag="PC366_001509"
     CDS             complement(7973..8989)
                     /gene="gap"
                     /locus_tag="PC366_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDF2577040.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYSDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEKEYDNQKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            complement(9626..10090)
                     /locus_tag="PC366_001510"
     CDS             complement(9626..10090)
                     /locus_tag="PC366_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 family lipoprotein"
                     /protein_id="HDF2577041.1"
                     /translation="MKKLVIILISIISVVSLTACKKSNESKYNNLNNKESGQTTIEMD
                     LDKNYDTSDPFVNARLFCVSNDIDVLDTEISFKMDGDSGIVEIKDNKTDETLWSNTWH
                     GSVDNDTFAISLSNIQKEKEYAICFTGIKINHAVVKVTFESNLVKEKEKPSK"
     gene            complement(10414..11022)
                     /locus_tag="PC366_001511"
     CDS             complement(10414..11022)
                     /locus_tag="PC366_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDF2577042.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSSE
                     QLKNIYLKNEEDSVDAVVIVGLHKSSKKLILIRQFRVPINGYIYELPAGLVDEGESID
                     ISVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDEFLEPDE
                     EIEALLISQEDAKEILQSNHKIDTKAFLILQMFVSLGAKLFE"
     gene            complement(11104..11805)
                     /locus_tag="PC366_001512"
     CDS             complement(11104..11805)
                     /locus_tag="PC366_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577043.1"
                     /translation="MKFIVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDMDFRNDDVYVRFSKKGDKFVPFGETDVELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            12032..12298
                     /locus_tag="PC366_001513"
     CDS             12032..12298
                     /locus_tag="PC366_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HDF2577044.1"
                     /translation="MKNFILIYFIVINSIAFFSMYIDKKRAIRNEWRIKEATLMSIAV
                     IGGSIGSMIGMYSFRHKTKHIKFTFGIPFILFLQFLLVYFYILK"
     gene            complement(12401..12820)
                     /locus_tag="PC366_001514"
     CDS             complement(12401..12820)
                     /locus_tag="PC366_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HDF2577045.1"
                     /translation="MDKISGKLTVLFEEPFWVGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDNIGYKRMQRKVKKEQEKETIGTKAQNALKLQY
                     EERKQDRKNLAKNRKEEEKERIFNLKQEKRKAKHKGH"
     gene            complement(13087..13869)
                     /locus_tag="PC366_001515"
                     /pseudo
     CDS             complement(13087..13869)
                     /locus_tag="PC366_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
     gene            complement(13934..14695)
                     /locus_tag="PC366_001516"
     CDS             complement(13934..14695)
                     /locus_tag="PC366_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HDF2577046.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQHINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWNGKRVFIIATMALFSGDGSGVLARILKKY
                     GAITVGGLHVKMPDSIGDEKVLKHSLEYNKKLVIKAEKKVTKAAKKLKHGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNMYTDKLKINTEECIVCGKCVNLCPMKNLVIKNCMIVAN
                     GQCTMCYRCVNNCAKKAITLLGKKVVEQSNIKKYM"
     gene            complement(15744..16556)
                     /locus_tag="PC366_001517"
     CDS             complement(15744..16556)
                     /locus_tag="PC366_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2577047.1"
                     /translation="MYLERPELYKQSEINFWDDEYISKQLLKAHLDTNFEGASRNFNF
                     IEDSVNWIVTVANPVNYPNLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSINYAQNRN
                     KETNLNINYLFQSYLNMNYNDEFDLATLIYCDYGALSTENRRLLMEKIYDSLKPGGKL
                     ILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTLVITEKD
                     ENVFYVWNHYFSKESFLLEVENIGFKSVEFFSNVKGEAYSDDSMTMGLVLQK"
     gene            complement(16926..17828)
                     /locus_tag="PC366_001518"
     CDS             complement(16926..17828)
                     /locus_tag="PC366_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2577048.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSMRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINSLFRHAKECNVHYVLP
                     GTLYLRGITRGVFFDFVKKEFPELFDKLSILYSAGSLNREYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDGQISFFD"
     gene            complement(17878..18339)
                     /locus_tag="PC366_001519"
     CDS             complement(17878..18339)
                     /locus_tag="PC366_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HDF2577049.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHLLVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTSILKWKNRNFANDISNEHSLNLENL
                     YDDWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWSGNIMF"
     gene            complement(18391..18846)
                     /gene="def"
                     /locus_tag="PC366_001520"
     CDS             complement(18391..18846)
                     /gene="def"
                     /locus_tag="PC366_001520"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDF2577050.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIKQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            complement(18818..19081)
                     /locus_tag="PC366_001521"
     CDS             complement(18818..19081)
                     /locus_tag="PC366_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2577051.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            complement(19178..19894)
                     /locus_tag="PC366_001522"
     CDS             complement(19178..19894)
                     /locus_tag="PC366_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577052.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYFLMFDLLLAFITPFMFFFASTMVILGEIDDSISRYLIVTPLGK
                     TGYLISRFGIPGTLAFIITMILLIFFSLTKISFLLNLSISLLVLLQGVIISILVISLS
                     SNKLEGMVITKFSGVFMMGILAPFFILNKAQYILFFLPTFWISKAFKEDNYIYMFISI
                     VISLIWILLLFKKFSKKIVK"
     gene            complement(19891..20568)
                     /locus_tag="PC366_001523"
     CDS             complement(19891..20568)
                     /locus_tag="PC366_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577053.1"
                     /translation="MRLKNLILGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IAIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMFIAITLNLDNIIISTIGTFFSSIIFSLLGLILASKASSLNQFIVLSIPIEIICFI
                     PPILNVLLDTKSYANLYPFNICISLISGDKNFIMINILISIIIIIYFITYYFICSSWK
                     KVGGVKL"
     gene            complement(20565..21410)
                     /locus_tag="PC366_001524"
     CDS             complement(20565..21410)
                     /locus_tag="PC366_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577054.1"
                     /translation="MIKVDDLSFSYTDRNFLQNINFEVEKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYGGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDELLKSVGLENEANKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKSKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVRYTYFDNGEKTSECFLNNTANDKNLNMLIKKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            complement(21524..22114)
                     /locus_tag="PC366_001525"
     CDS             complement(21524..22114)
                     /locus_tag="PC366_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2577055.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMEQYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRVDESITCEQLTDIFMKFYRMV
                     DSTSILNLMINGEFEILVRKLPDSIIEEHFRHDDFEIGEIISCIPNAKNKDIESFSGA
                     FRVVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
     gene            22403..22636
                     /locus_tag="PC366_001526"
     CDS             22403..22636
                     /locus_tag="PC366_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDF2577056.1"
                     /translation="MATTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
     gene            complement(22867..25254)
                     /locus_tag="PC366_001527"
     CDS             complement(22867..25254)
                     /locus_tag="PC366_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HDF2577057.1"
                     /translation="MKKFTSKKVARFVALFLISILVMSTIPVSADNSNTLNQIKKAEY
                     SDTYKQYLNDAKNGRTEKYNGIIPNPYQLEGTQIQSKGRTAPTSYDPRKLGLMTSVKN
                     QEDLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMDGALNYE
                     AMGYLTSWSGPKLEKDIPYNGRVSKAQGAKKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSGYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKDNFNANI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGKKPNDDEKMYQHD
                     YASIVPLISKKITAANVFDFNRGDETLKSVMFLTESIGAKYEVSYAPVVNGIPQENNM
                     KKLKEGTAQYSGYITVPIDSFNIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSNFYPCNFTIKAVTEKSSGESIPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGSSIVDALAATPFTSAINSPILLTQKEALNSKTKAEIQRLG
                     AKKVYLIGGENSISKEIEQQLKSLNISIERISGSDRYKTSLLLAQKLNGIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNAFVVKNGIKNQNDLIDGLAVG
                     PLGAKTGSPVILVGDKLADSQKEVLKNKTLEKVTQVGGGANKNAFKELVKLKSAK"
     gene            complement(25446..26201)
                     /locus_tag="PC366_001528"
     CDS             complement(25446..26201)
                     /locus_tag="PC366_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyglutaryl-CoA dehydratase"
                     /protein_id="HDF2577058.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKNTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGIYFLNKNIRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
                     CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKE
                     LVKMIEEILGKKIFIAEDTQIIGALGAAVIGFR"
     gene            complement(26226..27377)
                     /locus_tag="PC366_001529"
     CDS             complement(26226..27377)
                     /locus_tag="PC366_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HDF2577059.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRTAIKDKNEERELLKEFYALGKLEPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVQKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            complement(27577..28317)
                     /locus_tag="PC366_001530"
     CDS             complement(27577..28317)
                     /locus_tag="PC366_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HDF2577060.1"
                     /translation="MKDYEDVVYIKLVKKELEEWKKNILKKPSIFDKASKGIQNKFNG
                     VLPDKYHEIITSSIKVMTKTVLFGYKYATKPPLRNMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLMNNWDEYVNSLPEDINDFDWRTFQQEYRDYLDLAKFLQLMPGIGAFVG
                     FYVNGKLIDKLCETAVSAYRLRIRELKL"
     gene            complement(28389..29378)
                     /locus_tag="PC366_001531"
     CDS             complement(28389..29378)
                     /locus_tag="PC366_001531"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HDF2577061.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDVFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDHKKAYNLVKDKKILLELCPTSNVQTKTVDSYEVHPFYTFYKDNLHVSINT
                     DNRTVSDINLSSELNVIFDTFKLGLEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            29638..30891
                     /locus_tag="PC366_001532"
     CDS             29638..30891
                     /locus_tag="PC366_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:glutamate symporter"
                     /protein_id="HDF2577062.1"
                     /translation="MITLSFDIVQTLTLSIFFFLIGNLLKNKVNFLNNFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYKLKPSSNIGLSIPRYNRNLKRFGSKFFRNK
                     NRIKNNNFSETITPSVFLEQVLLIFICINTGEIISRCFYITFNILLPSVVTCMFSAVI
                     FRNLNDKINILELNFKLIDFLKELSLGIFLTLSLMNIDLFELSTLLPPILLIVTFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGDSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            30988..31212
                     /locus_tag="PC366_001533"
     CDS             30988..31212
                     /locus_tag="PC366_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2577063.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            complement(31428..32735)
                     /gene="grdB"
                     /locus_tag="PC366_001534"
     CDS             complement(31428..32735)
                     /gene="grdB"
                     /locus_tag="PC366_001534"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(31686..31688),aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HDF2577064.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDDAEIISTVICGDTYFGENIESATQELLKMIKEESPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVVTGMYKENPGVDMFKLDLHIVSTGNSAASLRKVVPIMTKLGLKLVR
                     GEEIGPPEEEGYIMRGIRKNFFHELRGSERAIDMLVKKMKGESFETEYPMPEFDRVTP
                     MKPVKDLSKIKLALVTSGGIVPIDNPDKIESSSATKYGIYDLTDMDSMSNKEFTTIHG
                     GYDRAYVLENPNLVVPLDVVRELEKEGVIGELVDYFITTTGTGTSVGNSKRFGEEFSK
                     KLLEDDVDAVILTSTUGTCTRCGATMVKEIERAGIAVVHICTVVPISLTIGANRIVPA
                     VGIPYPLGNPMLGEEESKKIRKNIVLKALNALTEDIEEQTVFE"
     gene            complement(32821..34107)
                     /locus_tag="PC366_001535"
     CDS             complement(32821..34107)
                     /locus_tag="PC366_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HDF2577065.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYISSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCRKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            complement(34386..35708)
                     /locus_tag="PC366_001536"
     CDS             complement(34386..35708)
                     /locus_tag="PC366_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HDF2577066.1"
                     /translation="MKILLVDDELEYGVVMKKILQKKGYLVDIALSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKSINRDIEVILVTGYGSIENAVDAMKRGALSYFIK
                     SNPIENLLEEVEKVKASKISVSVQKNNFEFTLESKNRDFNNIIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLTTLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIRP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKISEYNIK"
     gene            complement(35708..37702)
                     /locus_tag="PC366_001537"
     CDS             complement(35708..37702)
                     /locus_tag="PC366_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF2577067.1"
                     /translation="MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKP
                     NNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
                     LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDAVVGDEPVLRYY
                     INNYGLSNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEQVIENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIKNTFSENTN
                     KTSEIEIYNKILKINTFPVEYKKNNTEYIVVLIKDITNEKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIRNFIENIVKLQYKMLQLKNVEIKIDCEHNLVCYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGIKEDALKDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNKEVTI"
     gene            complement(37789..39036)
                     /locus_tag="PC366_001538"
     CDS             complement(37789..39036)
                     /locus_tag="PC366_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF2577068.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMANGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALFSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILLAMLGGGKAGNIISPNPNT
                     IAVADNFSVNLSSVMMANIIPAIIGVVITVILASILINKGNKVQSYEILEQREDLPSL
                     FKSLCGPIIAIFLLFLGNVSPIVIDPMIALPIGGIVTLIVTGNLNNSREYLAFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIGALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIVNAGSSVFEQLPHGSLFHTSSGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            39264..39809
                     /locus_tag="PC366_001539"
     CDS             39264..39809
                     /locus_tag="PC366_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2577069.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHDNRKKVILPGSKEVIYEILIPDSS
                     GNLEFAIMDLAPNTSSCIDRITHNGDEIAYVLEGEVKLFMDDDEFTLSKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            39823..40509
                     /locus_tag="PC366_001540"
     CDS             39823..40509
                     /locus_tag="PC366_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HDF2577070.1"
                     /translation="MKTYKFIFFDADDTLFDFKKSESHAFKKLLSEFDLEFNFENYIE
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKISLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILQYLKKKYTIVIITNGISAVQKKRLENSKIKGYIDGMVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALMIGNSLTSDVLGGINSGIDTCWLNSNNSINYTNHIPTYEI
                     NTLIELKKLL"
     gene            complement(40633..41253)
                     /locus_tag="PC366_001541"
     CDS             complement(40633..41253)
                     /locus_tag="PC366_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577071.1"
                     /translation="MNYNSNKNKYLLKDINLEDIFIDKNIVLKFLGYGNRKAPDTISE
                     IVEREIRNINDILDIKIYISEVDINKTPKECKKAFAVLYTIGDKIDIKMNDYMENCNM
                     MAGIALDKIGIVCLDYINEKIKMYLKGKYDSLKISHEIYPGDKDFEVERQKDIYNYVK
                     NKYNSIEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(41243..42265)
                     /locus_tag="PC366_001542"
     CDS             complement(41243..42265)
                     /locus_tag="PC366_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HDF2577072.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLETLRPDYDFPSVLTHTITDRDKLRKL
                     DVPDPYTSGRMPLNIESLSVISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEYIVKNLNKIYNEL
                     DCWKGMHICGDTRELLDNMLSCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRGYDNFLCDFGCNCLNTTPVENLQAAIKAGRINYKELDR
                     IDIDEL"
     gene            complement(42266..42904)
                     /locus_tag="PC366_001543"
     CDS             complement(42266..42904)
                     /locus_tag="PC366_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HDF2577073.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINLLKGTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNMIEIDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            complement(43022..44173)
                     /locus_tag="PC366_001544"
     CDS             complement(43022..44173)
                     /locus_tag="PC366_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2577074.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRNHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVVSDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIAYEIVEFDETNF
                     EKDDDLDKMLELYNQNSTRFIRTRDEFQKLLHAATIAWGPIGYKKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLEYLNYKVHVKNLKDQLKCNG
                     TESLDYQQGTMKIINFTKLCDSLRSYFSQYVDFELLKYMEFKQVENKYIIKYKEEELV
                     IENLDKLNKLFFEKNEEQYNEFKHLKNIYEFATKAFPVDFPWTANLNYQ"
BASE COUNT        14405 a         7608 c         4459 g        17865 t
ORIGIN      
        1 tattagataa tgtatcgttt atatcctttt ctactaatgg tttcatatta ttattataaa
       61 tacttatatc tgcattactt aattccattt ttatgcgatt aataagattt tctttatact
      121 ttgtaatatt aggtatggat ttaataaaca ttcttgatac agaaggtttt ttatctacga
      181 tatgacttag tatactatct atatttattt caattttatt atcaatatcc cactgagcat
      241 ttgcagagat taataacaat ccccttgttc gaatatatga gttttcgtta tcaatcattt
      301 ctaggaatga gtcaaaaaaa caatatgtaa tatttgattt taaactttca ttttctaaga
      361 ataaaaaagt tttatatgct tcattatgat tttttgaata taatttatta ataagtaaat
      421 tgagattctt caatcttctc atctccctca ttacaaatat ttatttaaac aaagtataac
      481 atattcaaaa ataaatataa ataaaaacta tattaaataa aaatcctaaa attatttgct
      541 gtttatttac aaataataat tctaaaatat atttgattta tttagtatcg actataaaaa
      601 taagctatca aataatttat acttgatagc ttattttctt ataattcttt ttttaaagtt
      661 tcctttagac tatcatatgc gaaatccatt atttctctac aagcaactaa atcttttttt
      721 aggtctatac ataactctga accatactct tttcttactg ttgtagttaa atctttagca
      781 tatactttag ctttagtact ttcatcttcg tggtttctgc cttttacgta tccaattatt
      841 atatttgatg catttactgc accacataaa ctagcaaccc cacaccctga acccagtcca
      901 cttcctaaac aaactggtat atctgtatta aattcctcat tatatgcttt tataactgat
      961 tctgcacaat taaatccctt ctcatgatat tttgatgcta taactttatc acacattaaa
     1021 attccccctc atttttgtaa attaaaataa attcttcatt gtttttgtaa aaaatacttc
     1081 tttttactat tattatatca aatattaaca ataaaaacat ttctttctaa gttaactctg
     1141 tctttctaaa tttaatagta tctctttcaa atcagaatga ttccccatat atccaccaat
     1201 attttttttg ccaactactc tatgacaagg tattattatt ggaattttat tacttttact
     1261 tgcttgtcct attgctctta ctgattttgg attgtttata tttcttgcta tatctgaata
     1321 acacaatgtt tctccataag gtatttttaa catttcccta taaactgatt tttgaaattc
     1381 agtcccttca atacgaatat ttaaattaaa gacttttctt tttccattaa agtaatcatc
     1441 tatctggctt attgcttcct ttaaatcttc cttacttatc tttatatcaa ttcctttttt
     1501 aatacattca ttttttaaat tattaaattt ttcatctcct atgtatacac taactataaa
     1561 accatcttca cttaatatgt acaaatttcc taattttgat ttataaacat catatactaa
     1621 actcatatta cttcccccct ttaatatcag tatacatata attttttaac taataaagag
     1681 ttaccctaaa aaataggata actctttttt atagatactt aatatagagt atatttttaa
     1741 attcattaac ttttaacata tcaaaatata aatcttatat atttttaaaa gccttagaaa
     1801 gcataagttt tatcctgtta agttgattta cctcacttgc agaagggtca taatcaatag
     1861 gtattatatt tgcattttta tacaacctct ttaattcttt tatagaaccc ttaccaatta
     1921 tgtgattagg taaacatcca aaaggttgca tacaaataat gttttctaca ccttcattta
     1981 ataattcaac catctcacct gttaaaagcc aaccttctcc agtttgatta cctaatgaca
     2041 ctactggttc tgtactttta gcaacatttt ttatattggc tggagcataa aatctctcac
     2101 tcttatcaag tgctttttta tatactcttt gatatattcc agttatgtat ataaatgctt
     2161 ctcctatcat tctactcttt ctacttcctt ctaaatgagt gtgtttgtat atagtattaa
     2221 aggcacaact taagaagaaa tttgtaaggt ctggcacgac tgcttcagca ccttctcgct
     2281 ctaatatatc tactaaatta ttatttgcaa ttggatggaa tttcaccaat atttctccaa
     2341 ccaaacctac ttttggtttt ttgatatcta gtatctctaa attatcaaat tcttttacta
     2401 tatcttttat atttctagta aatacagaaa tttttgcttt aacaagagaa gatttgcata
     2461 tatcaaccca tttttcatat agagcatttg cacttccagt aactttttca tatggtctta
     2521 ctctatatag tactttcatc agcaaatcac cataaacaac agacataaag agtctattga
     2581 ttaattttag tgatatatta tccattatac cactatcttc tattccattt acactaagtg
     2641 caatgacagg aacatcttta aatccagcat catatatagc ctttcttaag aatccaatat
     2701 aatttgtagc tctacaacct ccaccagtct gagttatagt aacagaagta ttatttaaat
     2761 catatttgcc agattttaat gctgttatta gctgacctac aactattata gctggataac
     2821 atgcatcatt atttacatat cttaaccctt cttcaattac actactatca gtatctttta
     2881 gaatttctat attataacca cttaagttaa cagctttttc aaggaattgg aaatgtattg
     2941 gagacatttg tggtgctaat atagtatgtt tgttcgttat ctgattattt ttagcatact
     3001 gtatcctgtt tacctttata ttttttacat ctatattttt gctttctctc tcaaacatag
     3061 ctgcttttaa ggacctcatc cttatcttag ctgctcctaa attgttgcct tcgtcaatct
     3121 ttataatagt atatatcttc gatttttcat taagtatttc ttgaacctgg tctgtagtta
     3181 ctgcatctaa tccacagcca aatgaattaa gttgaacaag ttccaaatag tttttatctc
     3241 ttacaaaact agctgcttta tacaatcttg aatgatatac ccattggtct acaactctaa
     3301 gtggtctttg tacattggct aaatgacata tagagtcttc agtaagcact gccatatcta
     3361 atgaatttat aagctctggc attccatgat ttatttctgg gtctatatga tatggtcttc
     3421 cacataacac aatccccttc atatttcttt cttttatttc tttaagtgct ctttcacctg
     3481 ctgcttgtat ctccatttta aataaattct gttcatcagt agctttatca actgcatgat
     3541 taacttcttc tttagttatt tttatatcag aaaaatgtct tgataattca tcatatagtc
     3601 ttttcttcaa tttttcctta tcatttagac ttataaatgg atttatataa tttatgttct
     3661 tatttcttat attctctaca ttgtttttta ttacttcaga atatgatatt acaacaggac
     3721 aattataata attatctgca tttgaatcct ctttattttc atttgttaca cttggataaa
     3781 atatattttt tatacctttt gcaattaaat tttctatatg tccatgaact aattttcctg
     3841 gataacaaac tgtttcagat gcaatactag ttataccagt ttcatataac tgttttgatg
     3901 acctatctga aagtacaact ctaaagccca tagcattgaa aaaagtaaac caaaatggat
     3961 aatcttcata catatttaat actcttggta tccctatttc cccatttttt gcttcttctt
     4021 tttccaatgg tttgtatcta aaaattctat tgtatttgta cttaaataaa tttattggtt
     4081 ttttcttttc taatcctatt tttttatcac cataaatagc ttcacccttc tcacatctat
     4141 tacctgaaat aaaaatttca ttatcagaaa atttatttat tgtaagaaga caatgatttg
     4201 aacaaccttt acatctagtt acacttgctt ctagcttgat attattcaac tcttccttag
     4261 ataacaagga tgttttgtat ccactttcat atttttcttt agctataagt gctgaaccaa
     4321 aagctcccat aattcctgaa atattaggtc taattacatt ttttccaatt agtttttcaa
     4381 agcttctaag caccaaatca ttataaaagg ttccaccttg tacaacaata ttattaccaa
     4441 tctcatttaa atctctaatc tttattactt taaataaagc attttttatt actgaataag
     4501 atagccctgc tgatatatct ccaacacttg caccttcttt ttgagcttgt tttactctag
     4561 aattcataaa tacagtacat cttgaaccta aatctacagg attttgagaa taaatacctt
     4621 catgtgcaaa ttcttctatt gtcatagata aagaacttgc aaatgtctct aaaaatgagc
     4681 cacaacctga tgaacaagcc tcatttaata ttatattatc aattactcca tcttttattt
     4741 ttaggcactt catatcttga ccaccaatat caagtataaa atctacatct ttattgaaaa
     4801 atttagcagc tttgtaatgt gctatagtct ctatctctcc gttatcgatt ttaagagctt
     4861 ttttaataag accttctcca tatccagtta cagttgaact caatatttta atattttttg
     4921 gtaatatatc atatacttca tttataactt taatggttgt ttttaatgga tttccttcat
     4981 tgctattata ataagaatat acaagtcttc catcctcatc aataagtgct gctttagttg
     5041 tagttgagcc tgcatcaatt cctaaataac aattgctttt tattgaattt atgtccacat
     5101 aacttatttt ttctttttca tgtcttcttg aaaattcttc atactcattt ttatctttaa
     5161 ataaaggttc taataaattt acttctccat cttcaatatt ctttatacta tccaattttt
     5221 ctattagaga ttttagttgt atattatctt catctactga taataatcct gctccaatag
     5281 caatataaag ttgtgcattt tctgggaaga ttatgttttc atcttttaaa tccaatactc
     5341 ttttaaatgc ttctctaagt tcagataaaa agtacaatgg accacccaaa aacgcaacat
     5401 ttccttctat ttttcttcca caagaaagga cactcacagt ttgtacgaca actgcattga
     5461 aaatactcat tgctatatca gtctgattgg ctccatcatt tataagaggt tgaatatctg
     5521 ttttagcaaa aacaccacat cttgaagcta taggatatat aacattatac cctttagcaa
     5581 gttcatttaa tccactggca tctgtcttta aaagtgatgc catttggtct atgaatgctc
     5641 cagtgccacc tgcacatatt ccattcattc tttggtctat tcctccactt agatatgtta
     5701 tctttgcatc ttcaccccca agttctatga caacatcagt ttcaggatga aaatactcta
     5761 ttgattttgt actagatata acttcctgaa caaattttac acctaatttt tttgatattc
     5821 caattccacc tgaaccagtt attataatgg tagtatttat atctcccaat ttttcatata
     5881 taccatttag tacttcttta actgattttt ttacatcaga ataatgtctt ctatattctt
     5941 tatgaactat attattacta ttattaagta ccacaacctt caccgttgta gaacctacat
     6001 caattcctat atgaaataat tcatccattg tacccctcca tatttatatg cttttttaat
     6061 ttttgtaagt tctatggctt tattttaagt aagttattta taatctttat gactaatatt
     6121 tttattttat gattctttta ttaatcaaag cttactctac taggtaattc ctaattctaa
     6181 ccttaaattt taaataagaa catatagtta gtgtactaaa ttttgtcata aatttctaca
     6241 gatttttgtt actttttaca taaatataac ttaagtctaa tatccactta atgtttatgt
     6301 attataaatt atctttagtc agaaaaaaat ggttgttgat atgtaaattc ttattacata
     6361 tcaacaacca tttttttgta tattattttt tatcttagct gattacgttt atcctacgag
     6421 tgtaaatata aagtgagctg ctgctcctgc acataaacca cctattgtat gagaaagaat
     6481 agctttacct gccaactgtc tagcatttaa tgcatccatc ataccaatat gtgtacttaa
     6541 atatccactc caacacatac ccatagctgt aaatactgct atatcattag gagttatagc
     6601 tcctgacttt ataaactctg gaactagaga cattgctgca ccaacagctc ccaatgaagt
     6661 tatagggaat gctattgcct ctggtgatgt aaatccaaat aatggttcta atataaatcc
     6721 aagtttatct ccaataactg gaagtaattt tattccttca tatgcagctc ctgtataaac
     6781 ttcttgacct gtaacagggt ctgtagatgg tccaaaagtt aataacatca ccaatgtaca
     6841 tactactagg actccaggaa ttatagccat tcccatatct acccccattt taccaccttc
     6901 aagaattgca tctaaagctc tttgaaatac atttccttct ctgatttctc taaattcatc
     6961 ctttttctct aatgttcctg ttgctttatc ttcttccgga ttgtatttat aaaacttctt
     7021 agtaaatgtc aacattattc taacacttat gacgctacct ataattgcac ctaaattacc
     7081 aattaatgct ggaagtacat attctgtacc ttgagaaatc ataaatgttg ttaagataag
     7141 tcccatacca aaggctgttc ctaagttaca taatgctgga acttggtatt gtttaaaata
     7201 ctgtgtgaat gttttatctt tagcaaaagg tataatagct ggattatctg ataaataagt
     7261 tgttatagct cctgctatac tagcaccagg tagtccatat aaaggcttca taaatacagc
     7321 gaaaatttta ttaattaacg ctattactcc aaactctgaa agtagtgcgc ttaatgcgcc
     7381 tgcaagaact gccatagcca taattaagaa aactgtctcc aatagtaaag catgtgctgt
     7441 actcattatt actttgaaca tcattcctgc tcccataata ctaccaacat acccaaaacc
     7501 aactactagt aatattagga aaatgaaggt ttccatgctt actgccttaa cctgtctcct
     7561 gtctgttaac ttctccattt tgaatcatcc cttctttttt tgttataaag tttaacaaaa
     7621 ccttttctct tttttaatta tacttataag tattactatt tgcaacttta tttgtcattt
     7681 ttttatcatt tttaaaatga aaatcagtat tttaataata aaaatttttc agatttatgc
     7741 aagttttcga catcttatct ttcattttat aaaaagtatg attccttact aaatatatat
     7801 atacttctct aacgacctaa tatgcaaata taagttgtaa cttgtatctt tttgcatgaa
     7861 agaaaaaaga ttatgaaaaa atttttcctt caatattttt cataatcttt ttttttagtt
     7921 ttatataatt ttttcaaaaa atttttttaa aatttgcttt aagaaatata tattatttta
     7981 atttttcagc tacatatttt actaagtcaa cagttcttga agaatatccc cattcattat
     8041 cataccaaga aactacctta accatattgt cttctataac cattgtggat agagcgtcta
     8101 taatagatga tcttgaatct cctttataat ctatagaaac aagtggcttg tcacaatatc
     8161 ctaaaacacc ttttaattct ccttcagcag catcttttaa cacagagtta acttgctcag
     8221 atgtaacgtt ttctttaagt tcgcacacta aatcaacaag tgaaactgtt ggtgttggta
     8281 ctctaagtga aaaaccattt aattttcctt ctaattgtgg tagtactctt gacacagctt
     8341 ttgctgctcc tgtagtggta ggtattatag attcagccgc tgctcttgct cttctcaaat
     8401 ctttatggct tttatctaat attctttgat cgttagtata tgaatgtact gtagtcatta
     8461 acccttttac tataccaaat ttttcgtcca atactttagc aaaaggagct agacaatttg
     8521 tagtacaaga tgcatttgaa attatattgt gcttttgatt atcatattct ttctcattaa
     8581 ctccgataac tatagttata tcttcatttt ttcctggagc tgttataatt actttttttg
     8641 ctcctgcttt aatatgtttt tctgcctttt ctctttgtgt aaataatcct gttgattcta
     8701 ttactatatc aacccccagt tctttccatg gtaattcttc tgggtcacta tatcttaata
     8761 tttttatctc tttagagttt actactagag tgtcttcatc ctttgcctct acttcacctc
     8821 taaaagttcc atagcatgaa tcatatgtaa ataaatgtgc caaagattct gttgttgctc
     8881 ttgcatttat ggctacaatt tctatattat ctcctaattc ttcttgagct attcttaata
     8941 cagctcttcc tattcttcca aatccgttca ttcctacctt aattttcatt atgaaatgtc
     9001 tccctccatt actatgtttt tacatgatta ttgtacacta aataaatcat ttgttcaata
     9061 ctttttcttg attaaataat caaattccat gtttttttat tatcaaaaga caattagtat
     9121 atcatttttc tttatttcac ccctcattta gtatgtactt tttagtgtaa ataagctgaa
     9181 atcatttatt ttactcaatg tcccttggga catattttgc catctttttt ttgaattttt
     9241 aaactatact tatttttaaa aataatatat cttcaagaat ctcctctaat ttaaaataat
     9301 aaaaacaaat ttttatttag ttcaaaaaat atatgatttt ttaaaatttg ccacaattat
     9361 tatttatata tcaaaatata aataataatt agcttattgt taactaaatt atggaaatat
     9421 acttaattga aaacttaaat ttatttcctt gtgttatcaa gatttcatgc ttaccatttc
     9481 caatatcatg ctcaccaact tttgatgtgc ataaactatt tcaagtaaaa atgcacaacc
     9541 tatccttttt gataggaaaa agcagtcaat cataaatatc aactgctttt atgtactgaa
     9601 tatcaagtta tagacaagct ggaatttatt ttgagggttt ttctttctcc ttaactaaat
     9661 tgctttcaaa agtaaccttt acaactgcat gatttatttt aattccggta aagcatatag
     9721 catactcttt ctctttttgt atattagaaa gagaaattgc gaatgtatca ttatcaacgc
     9781 ttccatgcca tgtattactc cataaagttt catctgtttt attgtccttt atttccacaa
     9841 taccactatc tccatccatt ttaaaagaaa tctctgtgtc taaaacatct atatcattag
     9901 acacacaaaa caaacgtgca ttaacaaatg ggtctgaagt atcataattt ttatctaagt
     9961 ccatttcaat ggttgtttgt cctgattctt tgttgtttaa attattatat ttactttcat
    10021 tgcttttttt acaagctgtc aagctaacca cactaatgat actaattaaa ataataacta
    10081 attttttcat agaatttatc tcctttacaa tttctaattt ttaaccctac aaactataat
    10141 attaaactaa tctactattt tacatcaaat ttttcaatca ttcagccttt accttttctc
    10201 attttaattg caaatatgct aaataatttt ggaattttaa ttattgtagt atcttaaatt
    10261 ggtttataac atattatgaa aatttaagag tcaagtaact tatttaaaaa tacacaaaat
    10321 tatactttat tgtataaaaa aagagattat aatttataca agtaaaataa actttattat
    10381 tttactcttc tatataacct cttttctata tatctattca aataatttag ctcctaaact
    10441 cacaaacatt tgtaaaatca aaaatgcttt tgtgtctatc ttatgattac tttgtaaaat
    10501 ctcttttgca tcttcttgcg aaattaaaag cgcttcaatc tcttcatctg gttctaaaaa
    10561 ttcatctgtt atatcaccat cacatataca ataaacaaag gcaacagatt catcactcat
    10621 tccaggagat aaataaactt tatcaatact tttatttttt ttaatttcta aaagagtaag
    10681 tcctgtttct tctctaagtt ctctttcaac agaaatatct atagactctc cttcatcaac
    10741 aagacctgct ggtaactcgt atatatatcc attaataggt actctaaatt gtcttattaa
    10801 aattaatttt ttactacttt tatgaagccc aactattaca actgcatcta cactatcttc
    10861 ttcattcttc aaataaatat tttttaattg ctcactactt tttcttgatg ctaccatcca
    10921 aaccttatct tcatctaatt tgtttttata ctctatttca aaaagtccta taaacttatt
    10981 ttcaatcatt ggatttacat tctttattat agtttttttc aaatttacta cgacctttct
    11041 tttttaatac ctttttaaca tcattaagta aatataatat cttaacaagt attcaacaac
    11101 ttattatatt tccatttcag gattatcttt atctacaaaa cctactttga tttcacaatt
    11161 aaatatttcc tttaacaatt ttgctaattc ttctcttgca ctcattacct tatctaaatt
    11221 agcatcagta aaaccatcta taggaaaaaa tatatttttt gagctattag taatttttcc
    11281 ttcctctcct tgtctccata tccatcttct agtttttacc atgtctccaa ctgaataaat
    11341 taattctcct tcttccatta attcaacatc agtttctcca aatggtacaa atttatcccc
    11401 ttttttagaa aatctaacat atacatcatc atttctaaaa tccatatcat gagcacccat
    11461 tggaagtaaa tattttaaag aaatagagtt tcctaaatct acaataggat ttatatgagg
    11521 aagtttctta ttcttagcaa cccttgttgt cattgcttct atcgaactca taaatttatt
    11581 tgggttcatg cctagacttc taaatgcctc tctatatggt ataatttctt ctgattcctt
    11641 tactttttta tctttgaagt aatcttctac tctatctata cttatatcta aaaggttgct
    11701 tattctttct atttctttag tattatctat tccttttgca actactacac caaagcatac
    11761 attttctaat ttatcaaaaa cttctttttc tactataaat ttcattttgc tttatcctcc
    11821 tgttatttta cattattttc taaatagatt ttatcacttt gtgtcttata aatatacccc
    11881 ctatttgcta attgtttaat ttttttaaat tttccaatta atattatatt tattcttatc
    11941 agatatttta tatgtactaa ttacaaattt aactttccaa aacaaatatc ttgttttata
    12001 atgtataata tatttttatg gaggcaagac tgtgaaaaat tttattctaa tatattttat
    12061 agtgattaat tctattgctt tcttttcaat gtacatagat aagaaaagag caattagaaa
    12121 cgaatggaga ataaaagaag ctactcttat gtctatagca gtaattggag gtagtatagg
    12181 ttctatgatt ggaatgtatt cttttagaca taaaactaaa cacattaaat ttacatttgg
    12241 tataccattt atactatttt tacaattttt attagtatat ttttatattt taaagtaatt
    12301 gaaatataaa accttattct tttcaataaa ttaaggtgta taaaattaaa aactttatac
    12361 acctttttct agcaattatt aaaaagatat ttaattaaaa ttaatgaccc ttatgtttag
    12421 cttttctctt ttcttgtttc aaattaaata ttctttcttt ttcttcttct tttctatttt
    12481 tagctaggtt ttttctatcc tgttttcttt cttcatattg aagcttaaga gcattttgag
    12541 ccttagtccc tatagtttct ttttcttgtt ccttttttac ttttctctgc attcttttgt
    12601 atccaatgtt gtctttggtc acattttttt ctaatttaat gctaccaaaa tctaatgaga
    12661 aaaatctttc aagtataaat tcatacactt ctacttcttt aggttctgct ccaaaaacta
    12721 ccctacatgc ttcatatttt ttaccatctt gtctttcaaa tatacctacc caaaatggtt
    12781 cttcaaataa gactgttaat tttccactaa ttttgtccat cgctagttcc tccttaaatt
    12841 actttctaaa gaacggacaa ccaaggaggc aggttactga cagctattgc tgcgtctgga
    12901 ctaccaacca gactgtgttt ttatctttat agattaaata ttatcttttt taatcatgct
    12961 tgtcaatctt agtatcaaca tctatcatat tgatttaagt gaaatcaagc tttttaactc
    13021 tactttatta ttgttaacac taagaaaatt aattattttt cataataaat tagttattat
    13081 acttatttaa atatcaatct ttattgttcc ctgcataaac aagactgctt caccagaaat
    13141 ttttacagta ttatccttca acacttcaca ctgaattata ccaccacgat tagaaagttg
    13201 agcagctacc attttgtgtt ttcccaactt ttcagaccag tatggaataa aattacaatg
    13261 tgatgaacca gtaacagggt cttctgaatc taattctgga caaaaatatc ttgatacaaa
    13321 atctgtatta cttccttgtg gtgtgattat tatacctaac cagtctgtca atttacgcaa
    13381 ttgtgcgtaa ttaggtttat aatttataac ttcttgttca ctgtttagca ataagattaa
    13441 atctcttgaa gaatagacag cacttggtac acagcctatc aaattagctt gttatggtga
    13501 taactctatt tcaataggca ttatttctgg aaatatcatt tcatatagat ttccatttcg
    13561 tgtaacttca agctttccac tttgagtaaa gaaatctatc ctttttacat taacatcaat
    13621 aaaatttgat attacataag ctgctgctaa agttgcatga ccacataaat caatttctgc
    13681 tttaggagta aaccatcgta attcataatt tcctttacct ttaactacaa atgctgtttc
    13741 tggtaaattg ttttcttctg ctattttctg cattaactct aaaggtatta ttctgtcaag
    13801 aacacaaact ccagcaggat ttcctttaaa tagtttagtt gcaaatgaat caactatgta
    13861 gtattccatt atttgacctc tctttccaac ataaaatata catcaattta cattcaataa
    13921 aactttaaat ttcttacata tattttttaa tattgctctg ctcaacaact tttttaccta
    13981 acaatgtaat tgcttttttt gcacaattat ttacacaacg ataacacatt gtacattgcc
    14041 catttgcaac aatcatacaa tttttaatta ctagattctt cattggacat aaattaacac
    14101 atttaccaca tacaatacat tcctcagtat taatttttag tttatctgta tacatatttg
    14161 ttttattgat aaaatacaat cgttgtccaa ataaccctac aatatgactc aaaaaaccta
    14221 acccttcttt tggtggtgac ccatgtttca gttttttagc agctttagtt actttctttt
    14281 ctgcttttat tacaagcttt ttattatact ctaaagaatg ttttaatacc ttttcatctc
    14341 ctatactatc tggcatcttc acatgtaatc caccaacagt tatagcaccg tattttttta
    14401 atattctagc taacacacca gagccatctc cactaaatag agccatagtt gcaataataa
    14461 aaacacgttt accattccac aaagttgaat gatttattat aaaatctttc aatatttttg
    14521 gcacattact atattgcaca ggataactaa aaataatatt ctcatgatta ttgatgtgct
    14581 gtaaaagttc attatcttca atagaataag aatttgctgt tatatcatat tcttgtaaaa
    14641 atttttctac acagtatctt gaatttcctg ttccactaaa atatattcct atcatagtac
    14701 ttctcctaat agctaagatt atatagctct attcttaaaa ttctgacttt ttatattatc
    14761 taaattaagt agtttattta aataatataa acttaattca acaagttacc tactgaacct
    14821 cccatgacta aagtcatagg gttcctgctt gatagaattt tacataatca atttactaaa
    14881 tacttgtcta attctttttt tatcatttta aatatacatt ttaataatat tagtaagcta
    14941 tacttcctta agcatatatt ttccctaaag taaaactatt gatgattatt ccattatata
    15001 acctaattat aaatttagta agttcatcac atactatacc cttaattctc aattataaag
    15061 ttccctaaaa aatatttgaa aatttaacta tgaaaagatt tcctattgcc taatatgtat
    15121 aagtaaggag tactatatag tactccttat attgtactct tataacattg ataccttaat
    15181 attattttaa tcttaatcat tattgatttg atttaaaatt ataaataggt tccaatattt
    15241 taattatgtc aactatatct cttatagttt taataatctc atcaattggt ttatgtgctt
    15301 gttgcacttt atcaatagta ttaattaaat ccatttacac atctagcacc tgtatggcaa
    15361 tttagcatta tccttatctt atactttgtt gtaaattctt gattacataa ttctattatc
    15421 taacttatag ctgtgcaatc tacattatct gtaaatatct ttgctttata tattttccct
    15481 gaacctctaa cattaatata acagcctttt tgctatacac ttttaactat atacttaatt
    15541 ttaataacat tacttgttta taaaaatata ctatagataa atttcacata aaaataataa
    15601 ttcaagtatt gatttttata taagaaaatt tgtaatgtac taaaaataac ataaaagttt
    15661 ccatttttca atatgtaagc ttttcttatg ttattttatt gttaaaggtt tcaagttttt
    15721 atttattcat tttaaaaaaa ttattatttt tgtaaaacta atcccatagt catactatcg
    15781 tcagaatatg cttcaccctt aacattacta aaaaactcaa cagacttaaa tccaatattt
    15841 tcaacttcta ataagaaact ttcttttgaa aaatagtgat tccaaacata aaatacattt
    15901 tcatcttttt cggttattac aagagtttgt tctaatgtat tataatcatt gtatttacaa
    15961 ttatcttgta gacacatata tttttcatta ctccaaaatc ctccatcttc atttatttcc
    16021 caatatttaa tttcctcaaa attattgtat ttatttattg taaatacatc taatattaat
    16081 tttcctccag gttttaaact atcataaatt ttttccatta ataaccttct attttcagtt
    16141 gacaaagctc cataatcaca ataaattaaa gtagccaaat caaattcatc attatagttc
    16201 atatttaaat aactttgaaa caagtaattt atgtttaaat tagtctcctt atttctattt
    16261 tgtgcatagt taatagaacg ttttgagaaa tcaattccag ttaccttata acctttttgt
    16321 gcaaatttct ctgcatataa acctggacca caacctaaat caagtaaatt aggataatta
    16381 actggatttg caactgtaac tatccaattt acagaatcct cgataaagtt aaaatttcta
    16441 cttgctcctt caaaattagt gtctaaatgt gcttttaata attgttttga aatatactca
    16501 tcatcccaaa aattaatttc actttgttta taaagctctg gtctttctaa atacatacat
    16561 aatttgttta acaaaacata ccactcctta aaatttattt ttaaaataaa aaaaccacag
    16621 agtttactct gtggtttaac ttcaaaaaga tgagtttaaa taagagtaaa atagaaccaa
    16681 atatttttaa gcacaacaat aaaactatag ctttactttg tttgcttatt aaatttgatt
    16741 ttattcactc ttttccagca atacttatat caacgatttt atgatatcaa atatcaccga
    16801 acaacatcat cctttcatat ttttatttta tgaatcaatt atatatttaa attttatatt
    16861 tgtcaataaa ttttaatttt aataaatttt aatcatcata gtaaaaaaaa attttttata
    16921 taaaactaat caaaaaaaga tatctgtcca tctcctgagt tttttaactt ttccttcatt
    16981 attttagagt aactgcttga tagagaatat ttatatctaa gttcattaac cattttatac
    17041 aattgatttt tatactccct attaagtgaa cctgcactat atagtattga taatttatca
    17101 aataattcag gaaactcttt tttaacaaag tcaaaaaaaa cacctctagt tatacccctt
    17161 aagtataaag tcccaggtaa aacataatgt acattacatt cttttgcatg tctaaatagc
    17221 gaatttatat tatcaaaatc atctgtaata tatggtataa ttggcataat atgtagacca
    17281 actgatgcgt tagtttttct aaattctttt aacattttaa atcgtctcat tgaatccaca
    17341 ccatttggct caataagcct ttgtgtatct tcatttactg tggtaattgt agatgctaca
    17401 ttgatatatg taatcctaga tagcttatca attaaatcgt aatctcttaa aattaaatct
    17461 gactttgtag aaataatagc tggtgtcttg tattttatca gcaggtttaa tatttctggc
    17521 ataattttat agtcagcttc tattggttga taactatctg taactcctcc tatattgatt
    17581 acttctttct tccatttact gcttttaagt tgtctctcaa gtttttctac tatatttgtt
    17641 tttacataaa tctcttcaaa ataattattg gagttaatgt acttatgaga gtaaatagca
    17701 taacaatatt tacatccatg ctcacatcca cgataaatat ttaaatccca tttatatggc
    17761 atactccttt ttaatttatt acaagctatt tcacaattta ttggaatata ttttatttta
    17821 ttatacaaat aatcacctct ttatatacaa taatactata atgttaatct atagtaatta
    17881 aaacatgata tttccagacc acaattcata atctttacta tatttacaaa gtaatatatt
    17941 ccattcattt attggtattc ctccacatgt tgctttttct tctaaattat ataagcattg
    18001 ctttaaatac attttattat gccaatcatc atataaattt tctaaattta aactatgttc
    18061 attagatata tcatttgcaa aatttctatt tttccatttt aatatacttg tatatttaag
    18121 ttcattaggt ttataatttc tttttaacat ttcatcatgt acaatttttg tataaaattt
    18181 aaattcatct atactataat tcaatacttt attcactaat agatggtttg gagtaccttt
    18241 tttatctata gaacctttta tagcaagtag ctctctccat tgacttacta attgattttt
    18301 aggtaataca tcaattaaat ccttatgcca taatctcata atttaactcc ttactataaa
    18361 atattttata aattcaataa ccaatctatc ttacaatttt acatgttcaa taattttatc
    18421 tgtaaaaact ataccattta aatggtctat ctcatgacaa agacattttg ccataaaacc
    18481 tgaaccttta atttctattt tctcaccgta ttcgtttaga gcttgcactg taactttttt
    18541 tggtcttttt aatttacccc atacttctgg aaaacttaaa catccttcaa caacaatttg
    18601 ttccccttct tgtttaataa tttcaggatt aacaagctta ataagtcctt ctcctaaatc
    18661 tataacaact aatcgcttta atactcctac ttggcatgca gctaatcctc ctccatttgg
    18721 agtattgtac atggtctctg ccatgtcatt taatatttct cttatcttat tatctacgtt
    18781 ttctacatac ttactctttt ttcttaaaat ttcatcatca aatgttctta tctttcttat
    18841 agccataata ttctccccta cttatctgtg ctcttgattt tctttcactt tcttcaaata
    18901 aaaatacact ttcaattggt tcattaaaaa ttcttgaaat atcatatgcc aaccatattg
    18961 aaggttcatt tttaccagtt tctatagcat ttatagcctg tctagatgtt ccaactaatc
    19021 ttcctagttg ttcttgtgtc aatcctaatt tttctcttaa tatctttatt ttatttttca
    19081 tatttgctcc attcatgtaa ggttaacttt acatcttaaa tgtaacattt ttcaacatta
    19141 ctgtcaagtc aaccttacat ttatatatta aattttctta tttaactatt tttttactaa
    19201 actttttaaa taataataaa atccatatta atgatataac aattgaaata aacatataga
    19261 tataattatc ttccttaaat gccttcgata tccaaaaagt tggtaagaag aacagaatat
    19321 attgtgcttt atttaaaata aaaaatggtg ctaaaatacc catcataaaa acacctgaga
    19381 atttcgtaat taccattcct tctagtttat ttgatgataa agaaatcact agtattgata
    19441 taataactcc ttgtaataaa actaataaag aaattgataa gtttaacaag aaagaaattt
    19501 tagttagaga aaaaaagata agtagaatca tagtaataat aaatgctaag gtacctggta
    19561 ttccaaatcg tgaaataaga taaccagttt taccaagcgg agttactatt aaatatcttg
    19621 aaatgctgtc atcaatttct cccaatatga ccattgtaga agcaaaaaag aacataaaag
    19681 gtgtaataaa agctaaaagt aaatcaaaca tcaagaaata cggctctaaa tttaattgat
    19741 aataaaactt gttaagtgat atattctgta ttaatggtat tccaaatttt ataaatactc
    19801 cacataatat tggagaaaca catactataa aaagcatagc atctctctta atttgttcaa
    19861 actcttgttt aaacgcattt ataatcttta tcatagtttt actccaccta cctttttcca
    19921 actgctacaa ataaaataat aagttataaa ataaattatt attataattg atattaaaat
    19981 attaatcatt ataaaatttt tatctccact aataagagaa atacatatat taaaagggta
    20041 caaatttgca tatgattttg tgtcaagaag tacattgagt attggtggaa taaagcatat
    20101 aatctcaata ggaatactta aaacaataaa ctgattcaaa ctagatgctt tacttgcaag
    20161 tatcaatcca agcaaagaaa atataataga agaaaaaaag gtacctatag ttgatattat
    20221 aatattatct aaatttaatg taatagcaat aaacatagct acaatactag atattactcc
    20281 taatgaaatt acctttgata aaatatactc agatactttt actggagata cagctaagga
    20341 atttaaaacc ctttgacttt tctcaagaag tacaatagct cccataaaaa acaatcccat
    20401 tgctgctggg tcagaataaa tcataattat agctattttt tctctcataa aagttggaaa
    20461 tacattgata atacaaatat atataatact taaaaaaaga tataaaaaat aaaaaccata
    20521 cttaaattga aactttatat ctcctaaaat aagatttttt agcctcattg taaattcctc
    20581 cctgttatct caataaaaat atcatttaat gttggttcac tactatgtat tgataaaagt
    20641 ttatttttct taataagcat attcaaattt ttatcattag cagtattgtt cagaaaacat
    20701 tcagaagttt tttctccatt atcaaagtaa gtatatctaa ctttaatagc tccttttgac
    20761 ataataagat tatgtggtgt atctaaagca gatattttac catttacaat gaacgctact
    20821 ctgtcacaaa gctccgttgc atctaacatg ttatgagttg ttaaaataat agttttacct
    20881 ttagattttt ctgataaaat tatatctttc ataaccttgc tatttgacgg gtcaagacca
    20941 cttgttggtt catctaaaaa taaaatatct ggattatgta ataaagcttt tataaaattt
    21001 aatcgagatt tcataccttt tgaatactca gatacccttt tatttgcttc attttctagt
    21061 cctactgatt ttaataactc atcaatagat agtagttttt tagaatatag agacccaaaa
    21121 tattttaaat tttctattgc agtcaacttt tcatataaac taggaaattc aaaatcaact
    21181 cctatatttt cataaaattt atttgagtgt cttttactct ctactccatt tacaatgaca
    21241 cttcctccat aattagttat cattccaatt agaatctttt gtaatgtaga ttttcctgca
    21301 cctgatggtc ctaaaaatcc tagtatttcc cctttttcta cttcaaagtt aatattttgt
    21361 aaaaaatttc tatctgtata actaaatgat aaatcatcaa ctttaatcat tcaatatcac
    21421 cctttcaaat ttttgactat tttgactata tggtcaataa aatataattt ttttgtttgt
    21481 taataatttt taataaaagt tattagcaaa caaaatttaa attctattcc ataagttgta
    21541 taactaatcc gtttatcatt aatcttaaag catcttcaaa acaattactt ccaacctcgc
    21601 gcttatatag catggtaaga aaaactactc taaatgctcc actaaagctt tctatgtctt
    21661 tattttttgc atttggtatg caagatataa tctctccaat ttcaaagtca tcatgtctaa
    21721 agtgttcttc aattatagaa tctggtaact ttctcaccaa tatctcaaat tctccattta
    21781 tcatgagatt taaaattgaa gtactatcaa ccatcctata gaatttcata aatatatctg
    21841 tcaattgttc acatgtaata ctttcatcta ctctatttat ctcatataag atttcttttt
    21901 gtatagagtc atgtatatct ctcaatacct caaaaaagag caattctttt gattgaaaaa
    21961 atagataaaa agttcctttt ggtattttta cccgttttac aagctcatca acagtagttt
    22021 ttctaatacc atattgctcc atacacaatc ttgcttcttc tttaagtctt tttattatat
    22081 actctctttc tttatcagaa tacgatttag gcatcttttt cctccagttt gactaaaata
    22141 atttatatag tcaatataat actttttcta tctaatgtca atagtattat tagtatattt
    22201 aaaaataagc ttaaaaactt tcgaaaattc tgaattttat atagcatttt ttattatcta
    22261 gtgttataat taagatataa ataatatatt attctaattt tcatatctat ttgcttattt
    22321 tttaacttag tttctaatag aagtactcat atttatcttt ttaaaagttt caactttaat
    22381 aaaaaataaa ggagttgatt ttatggctac tactacaaaa aaccgttttt acgattatgt
    22441 tcaagaaaac ttaaataaat atgttgaagt acattcttac tttagcagtt gtcctctata
    22501 tggtgaaatt atagaagcag atagcttatc aattacactt tgctcaagat atatagatga
    22561 atctaatcca actttaaatg aaacttacac attatattta ccattaagtt caataatatc
    22621 tattagaaca ctataaaaag ttaattaaat atgggttatt tatatataaa atataagatt
    22681 ttctatattt ctatatatag taaccctttt ttatgttttt aaacttatac tacataaatt
    22741 taaagctgaa aacaaaactt tacaatcatt gattatctta tttatcaata atttaaagta
    22801 attattttca gcttttatta agataagtta ctaatacaca ctaatatatg ttaatactta
    22861 agtactctat ttagcacttt ttaattttac taactcttta aatgcatttt tatttgctcc
    22921 tccaccaact tgagttactt tttctaaagt cttattttta agaacttctt tttggctatc
    22981 agctaattta tcaccaacta aaattactgg tgacccagtt tttgctccta aaggaccaac
    23041 tgccaatcca tctattaaat cattttgatt cttgattcca tttttaacta caaatgcatt
    23101 ttttaaagta tcttttttat aaaaattatc tattatcttt gaattagttt cgtctctact
    23161 actaccagat aatctagttg gattttttaa cttactttct agattgtttg atagggatgc
    23221 tgttcctcca ataatataag atttctctat atttaatgaa tttagaaatt catcagctcc
    23281 ttgcaattcg ctcttttcat ttgcaagtat gattggtatg ttattttctg ctgcagcagc
    23341 acctacacta attgcatcag ctaatccttt cactccattt acaactgcta tttgagatac
    23401 attttttata ccatttaact tttgagctaa taataaactt gtcttgtatc tatcacttcc
    23461 tgatattctc tctatcgata tatttaagct ttttaattgt tgttcaattt ctttacttat
    23521 agaattttct ccgcctatta ggtatacttt cttagcacct aatctctgta tctcagcttt
    23581 agtttttgaa tttaaagctt ctttttgtgt caataatatt ggtgaattta tagcagatgt
    23641 aaaaggagtt gctgccaatg catctactat tgaactgcca tttactaaaa ctacattttc
    23701 tgaagaattg aaaccatttt gactaacttt gatagcagtt tcatatctat cactaccaat
    23761 taaagactca ttcgggatac tctcaccaga agacttttct gtaacagctt ttatagtaaa
    23821 attacacgga tagaagttac tatctctatt tatatcaaag aattttccag tattatctat
    23881 gatataactt tcacctaaat tagcttttgc tttaaatgta tcatatcctg gtacatttga
    23941 ctcagaacct atagttgact ctccattttt cccctctata ctgactacaa ttgcaccctt
    24001 tccttctggt atattaaaag aatcaattgg aactgttatg tatcctgaat attgggcagt
    24061 accttctttt aattttttca tattgttttc ttgaggtata ccatttacta ctggagcata
    24121 agatacttca tacttagctc ctatactttc agttaagaac attacagatt ttagagtttc
    24181 atcgcctcta ttgaaatcaa atacatttgc agctgttatc ttttttgaaa ttaaaggtac
    24241 aatacttgca tagtcatgtt gatacatctt ctcatcatca tttggttttt taccaccttt
    24301 gattgaaaaa ttatctatat cagacataag tgtcttgtct tcataagata tccagaaata
    24361 tccaccctca gaattataat ctccccagct attttttatt aaccaagcac cattttttga
    24421 tggtctaata tttgcattaa aattatcttt agaatagtta tcatcccaac ccacaattga
    24481 aatagcatga tttgtattaa aactttttgt tggacaataa tatgaatttt ggtcatcact
    24541 ttgatattta atatcttcat aataaccaga tgttactgct ccatactgta atatagcatt
    24601 ttttgtagaa tttatgtcat tacttacaca cacagcatct gtcacattaa aaacagtagg
    24661 tgctgtattc atattagttg gtttttttgc tccttgtgct ttagatactc taccattgta
    24721 tgggatatct ttttctaatt taggacctga ccaagatgtt aaatatccca tagcttcata
    24781 atttaaagca ccatccatat catttacaga ccatccatat tcaccatctg aagcccacca
    24841 tcttaagtgt tcttctgata aatcgtagtc tccataatta tttaacttca agaaactttc
    24901 caaggttgcc attgcagcaa aatcccagca tattcctaaa tcctcttgat tttttactga
    24961 tgtcataaga cctaattttc tagggtcata agatgttgga gctgttcttc ctttactttg
    25021 aatttgagta ccttctaact gatatggatt tggtataatt ccattatatt tttctgtacg
    25081 tccattttta gcatcattta gatattgttt ataagtatca ctgtattctg ctttttttat
    25141 ctgattcaat gtattgctat tgtcagctga cacaggaatt gttgacatta ctaaaataga
    25201 tattaaaaac agtgcaacaa accttgctac tttttttgaa gtaaattttt tcacgctttc
    25261 tcccccttat tttgagctaa tttttaaaat tctaatgtta tatatgacta aatatcaagt
    25321 atttacaaat atacaatcat ttaaatcaat tataccaaag ttttccttta taaataaaca
    25381 aaataaaata aaaaactgaa cttatttatg ataaattcag cttttcattt tctttttata
    25441 tgtttttatc taaatcctat tacagcagct cctaaagctc ctattatttg agtatcttct
    25501 gcaataaaaa tttttttacc cagtatttct tctatcattt ttactagttc tttacttttt
    25561 gcaagccctc cagtaaatgc aacttcatct attacctcac ctcttgctaa cattgaggtg
    25621 gatttatttg caatagattt aagtatccct gctgctacct ctccagtaga aatgttttga
    25681 gctagaagac ttacaatttc agactcagca aaaactgtac acatactaga tatattaact
    25741 ggttcatatc ctttagctaa tgtatctata ctttcaatat cgcttcctaa aaggttagaa
    25801 gtaatctcta aaaatcgacc agttcctgca gcacacttat cattcattat aaagttaaat
    25861 acatttccat ctctatctaa atttataact ttactatctt gaccacctac atctaaaata
    25921 gtccttatgt tcttgtttaa aaagtaaata cctctagtat gacaagttat ttctgttact
    25981 ttcttatcag caaaatccat tactcccctt ccataacctg tacctaccac cttttttata
    26041 tcttttttgt caatttcact acttagcaac tcatagacct gtttagatgt atttttaggg
    26101 ctccatccag ttggtataat tattttctta ataatttttt caccatcaaa tagcacaccc
    26161 tttgttgcca ctgaccctga gtcaactcct atactaaaca tagttcctcc tacttttatt
    26221 tattcctaca acatctctac aaacgcttca aatctagttc ttaattgttc agtatctgat
    26281 tttgaataat cagtttcaag agacataaat ggcttatttt tttcttttgt aacaaattct
    26341 cttattctat aactttctat attaaatgta tgacatgctt gtaaaactac atctattaca
    26401 gcatctacat tatattcatc tattattcta tctaataatt caatacgatt gtcattattc
    26461 atcatacaag aacaacctat atttatatat ttttgtgtta aagcatcata tacatcttct
    26521 atttcttcat caaccaataa atcgtttgat ctaatagctc cacaaagttc atatgcaacg
    26581 actgatgccc ctgcatcttc taaagtttta actatttttt cgcttattcc accaatagga
    26641 gaacctgtta tcaatattct tggcttatct ttttgaacag gacattcacc tttttcatat
    26701 ctttctttca tatcatctat aacttttctt aaagaatgtt taagttctgc acggtcaaat
    26761 ttaaaacctg cttgatataa aacattatgt aactcaaggc ctgtaagtgc agatggttct
    26821 aatttaccaa gtgcataaaa ctcttttaaa agttctcttt cttcattttt atcttttata
    26881 gcagttctta tatcttcttc agttatagtt acacctaaag atttctcaac ctcttctttt
    26941 aatcttatca tttcatcttt ccaaagttta taggcaaatt ctccttttga agtatttggc
    27001 aaatgcatta catatgttgg cttaactttt gcaagttctt catacatttt tttcttacca
    27061 tcacaagtgg tttctcctat caacaaatca gaaaaataga aataaggaca ggtgtctgtt
    27121 attgcatgtc catagcttga tttaattaaa ggacaaagat ttcttggaag caccctttct
    27181 gcatcaggta ttggctcttc actaacaccg catacaccta ctacagttgc tccagctgcc
    27241 attggaattt caactggagt aaatgtacag aaaactccaa ccatcttttt cccactttcc
    27301 ttaagttcct ttgcatttat aaatcccttt tgtctagctt cattgaagct atcaaattgt
    27361 tttggcaaat ttgtcatgaa aatattcctc ccaattactt ctcttcgtaa ttcaatttgt
    27421 atcttaagca ataaaaacta aatttttcca ttaaaataca aacctctaca ttagattcta
    27481 tcatgcttta ccttttatcc ataattgttt ttatcaatgc aaaattagat acatatagat
    27541 atattgtata actaattttt tatgttataa tttctcttat aacttaagct ctcgaatcct
    27601 caatctataa gcagacacag cagtttcaca taatttatca attaattttc cattcacata
    27661 aaatcctaca aatgctccta ttccaggcat tagttgtaaa aacttagcta aatctaaata
    27721 atctctatac tcttgttgaa atgttctcca atcaaaatca ttgatgtctt ctggtagact
    27781 atttacatat tcatcccagt tattcatcaa tttaaaagtt ttgtttatat gctgttgact
    27841 agaaaaagcc aactgtaata tgtttaatat ataaatcctt tctctataat ctttaacatc
    27901 atatccatat attgaagcta catcatataa aaatttcact ttaataccta aaagcaaagg
    27961 aaaatcagat aaacctaaga ggattcctcc tgcccctgtt cctgcccctt caatcattgc
    28021 tgtggtcttg taagttttag ctttttctaa aactaatttt tctctttctt ctaatgacat
    28081 atttctaagt ggtggctttg tagcatattt atatccaaac agtacggttt ttgtcattac
    28141 ttttatagaa gaagtaatta tttcatgata tttatctggc aatactccat taaatttatt
    28201 ctgtataccc tttgatgctt tgtcaaatat agaaggtttc tttaatatat ttttcttcca
    28261 ttcttcaagt tcttttttga ctagtttaat ataaacaaca tcttcataat ctttcacatt
    28321 ttttctccta atacaatgta tttttgtcaa tttaatagct taatttaaag tttaaatatt
    28381 tttatctatt aaattaaact attcaaatac tctttagttt ctttatctgc aaaactagct
    28441 tctactgcat ttctataaat aattttatag tcttctaatc ctagtttaaa agtatcaaat
    28501 ataacattta gttctgaact taaatttata tctgatacag ttctattatc agtatttata
    28561 cttacatgta aattatcttt ataaaaagta taaaatggat gtacctcata agaatctact
    28621 gtcttagttt gtacattact agttggacat aattcaagca atattttttt atctttaact
    28681 aaattatacg cctttttatg gtctttaatt tttaccccat gaccaatcct atccgccttt
    28741 aaaatattta tagcatccaa tacattttct ccacttgcag cttctcctgc atgtattgta
    28801 actttatatc catattctct tgctaattta aaaacatctt tatattcctt acaaaatccc
    28861 tctttctctg gaccacacaa gtctactgct acaacacctt tatttacaaa tgatttccct
    28921 tcttcaatta ctaataatgc ctcttttgag gtcattgttc tcatacaacc taatattaaa
    28981 ttgcctttta tatcataaat actttcagct tctctaattc cttcaattat accctcaatt
    29041 atatttttaa cactcatacc tttttgggtg tgaagtaatg gtgcaaatct aatttcaata
    29101 tattttacat tttctctact tgcatcttcc aaaagttcaa aagtaattct ttttaaattt
    29161 tccttagatt gcattacttt taagggtaaa tcaaattttt ctaaatattc atctagtgaa
    29221 gtacaattaa aagaaacctt tgctaatttt tttatttcat ccatattatt tgaaggtaaa
    29281 tctattttct ctttaatagc tatatcaagc atggtttcta ctctaacact tccatctaag
    29341 tggcaatgta aatctatctt aggtaaattt tcaaacattt tatcctccta ctgtacttat
    29401 aaataatact atcaacagat ttttaagtct tatttctatt atatcaatat actacggttt
    29461 ttcattctaa aaaagtcaca tctcattaaa atattttaat ttaatttatg actatctaat
    29521 tatatatact gattcttttt aatatacatt tattaatata catttgataa taaaatttca
    29581 atacataaga atttaagtta tataattaaa actttgaatt acaaaggagg acttattttg
    29641 attaccttaa gttttgatat agtgcaaacc ttgacactat ctatattctt ctttttaatt
    29701 ggtaatttat tgaagaataa agttaacttt ttaaataatt tctgtatacc tgcaccagta
    29761 ataggaggtc tattattttg ttttctaaat ttatttttta aatattttaa tatagcagat
    29821 atatctataa gtggaaattt aatgccaaat tttataacct tcttttttac aactatagga
    29881 cttgaaataa gcataaatct tataaagaaa ggtggtagtg tattatttag atattggatt
    29941 ttgtgtggag tattggcatt ttgtcaaaat atattagcta ttacaatatc aaagattata
    30001 aaacttgaac ctcttttagg gcttatgtgt ggaaatgtat ctatggaagg tggtcatggt
    30061 tattctgctg catttggact tacaatagaa aatctcggta tagaaggagc agttggggtt
    30121 ggattatctg ctgcaacaat aggacttatt atgggtggta tattgggatg tcctgtagct
    30181 aaatttctaa taaataaata taaattaaaa ccatcatcaa atataggctt gtcgattcct
    30241 agatataata gaaatctaaa gagatttgga agtaaatttt ttagaaataa gaataggata
    30301 aaaaataata acttctccga aacaataaca ccatctgtat ttttggaaca ggttcttctc
    30361 atatttattt gtataaatac aggagaaatt ataagtagat gcttctatat aacgtttaat
    30421 atactattac cctctgttgt aacttgtatg ttttcagctg ttatttttag aaatttaaat
    30481 gataagataa atatattaga attaaatttt aaacttatag attttttaaa agaactttca
    30541 ttgggaattt ttttaacttt atcacttatg aatatagatt tatttgaatt atctacatta
    30601 ttacctccta ttctcttaat agtaactttt caagtaatct ttataatcct attttcaata
    30661 tttatttgct ttagagtact tggaaaagat tttgattctg ccatcataat aagtggtttg
    30721 attggacatg gaataggagc tactccgaac gctttggcaa atatgagttc tttgacacaa
    30781 aaatatggtg attctccaaa agcctttttg gttgtaccat tagtaagtgg ttttttgcta
    30841 gatgctatta gtatcccatg tatactattt tttataaaca tactaactta gtatgtttat
    30901 tttttgttat atattgacaa tttactcttt ttgttatata ttataaatat aaagtttgat
    30961 aatgattttc attaggaggt gttaataatg actgtttaca acttaaaact tggacaaaag
    31021 ggaattatag acaatatagc tggaaatgaa aaacttatga agagacttct agccttagga
    31081 ctaatagatg gcactgaagt tgaagtgaaa aagatagctc ctcttaatga ccctatagtg
    31141 attagattta gagggtttga cttagctatt agaaaatctg atgcaaaaaa tataaattta
    31201 aaaaataatt aatatataat aaaaagagat tttaaaatct ctttttttgt ttatgtataa
    31261 tcttctattt atttttttca ttctttatac tttaattggc tgttttacta taaatatttt
    31321 tattacttaa ttgctttctt cattccatcc atagcaaaaa gatatcataa aataattttc
    31381 aaaaactatt ttatgatatc tttttttatt tctatattat atttttatta ttcaaatact
    31441 gtttgttctt ctatatcctc tgttagtgca tttaaagctt ttaaaactat attctttcta
    31501 atttttttac tttcctcttc tcctaacata ggatttccaa gtggatatgg tatccctact
    31561 gctggaacaa ttctattagc tcctattgta agtgatattg gtactactgt acatatatga
    31621 acaactgcta taccagctct ctcaatctct tttaccatcg ttgctccaca acgagtacaa
    31681 gtacctcatg tagaagttaa aattacagca tctacatcat cttctaacaa tttcttagaa
    31741 aactcttctc caaatctctt agaattgcca acactcgttc ctgttcctgt agtagttata
    31801 aaataatcta ctaattctcc aattacacct tctttttcaa gctctctaac tacatctaat
    31861 ggtacaacta aatttggatt ttcaaggaca tatgctctgt catacccccc atgtatagtt
    31921 gtaaattctt tatttgacat agaatccata tctgttaaat cgtaaattcc atatttagta
    31981 gcacttgaag attcaatttt gtctggatta tcaattggaa ctatccctcc agaagttact
    32041 agggcaagtt ttatcttaga taaatcttta acaggtttca taggtgtaac tctatcaaat
    32101 tcaggcattg gatactcagt ttcaaagctt tcccctttca tctttttaac caacatatca
    32161 attgctcttt cagaccctct aagttcatgg aagaaatttt ttcttattcc tctcattata
    32221 tatccttcct cttcaggagg tcctatttcc tcacctctaa ccaatttaag acctagtttc
    32281 gtcattattg gaactacctt tctaagactt gctgctgaat ttcctgtaga cactatatgc
    32341 aaatctaatt taaacatatc tacacctgga ttttctttat acattcctgt aactacagga
    32401 atatttaact cttcttcaac tgccttacaa atagtcccac aagctactcc atatctacct
    32461 gcattaaatg ctgggcctgc aataaataaa tcggggcttt cttcttttat catttttaaa
    32521 agttcttgag ttgcactctc aatattttca ccaaaatacg tatctccaca aattacagtt
    32581 gagattatct ctgcatcatc attaaattga ctctgaaatg ctattccagg tcctactaca
    32641 ccagcccttt tttctggcgg aatatctgct ttttcctctc cacctatacc agcaaagaaa
    32701 ttgtttatat aatgaaccac tctgatttta ctcatctctt aatcctccaa atcactttat
    32761 agttattaca tcaattagac caacgattac atcaacagaa ctttatattc aaatacttat
    32821 ttaataatat cttgctgtca aatgattata gccatttgct atagttgatg ctattataat
    32881 ttgtagctct gcatccatgc ttccgtcttc atttaagcat cctttatacc cacctatcat
    32941 catttcaaca taatctaaag ttcctataat tttttccatt gctgggaaat gaaccactag
    33001 atttccttga ccacaagaaa caactgcatc tgcttcctta gtagcgtctg ctatagattg
    33061 actcttgcca tcttttccag gaaattcatc cgttatcaaa actacatttg ctccaacttc
    33121 actacatttt ctacaattca tcattaggtc agtatctgga ttcccataac cttcttctgt
    33181 cactagaact ccatcaactc ctaaaaattc tattaattta gctaccatat cagagcttct
    33241 ctctttatcg actaagaata cgttctcatt agtcaaaata actcctataa agtttaaatc
    33301 ttttccatgt cttttatata agtcatgtat aactggatta tttaaatgat ggaatgttgt
    33361 aaccttatca catggtgcta cacagtttcc agatattata gctccatcca ttatttcagt
    33421 tggatacata aatgtaggca ctatctgttt agcatccacc ccatagtaat aagtgtcatg
    33481 taaaagtcct tgtgattgta acatgtgaac atatgctact gttggcaggt ctggatattc
    33541 ttttacttgt tttaataatg gctttgtctc atatacaatg acttcatctg gctcaacttc
    33601 tcttcctgcc tcacctacat atgcacctat ttttaatcct gcaattctag ctgcttcttc
    33661 ataatcatga gtatctatac catcctttgc ttttataaca atacatatat tatttgtttt
    33721 tgaaaaaggt gtatatttag cagtaggacc actcatatca attacgcctt cttgaaatcc
    33781 aactatattt ccacaagtta caacacaagc tcctaaaagt acatgggttc ttccacttcc
    33841 tacagtcttc actttattta taattccagg aaatattttg ctttcatctc caattttaac
    33901 tctaggctct attacatctt taactggagc tattcttatt gattcgccag gtcttgcaag
    33961 ttcaacattt acacttacaa tcctttcatc ttctaatact atcttttcta tttcttcgct
    34021 actaatatat agtactccat cttttacttc tgtcttttct ccaaattcaa cattttttat
    34081 aaatatattc cctagctcta gcttcatatg aaaatccccc ttaatatatt taatcgcaat
    34141 taaaaatatt tattacgttt attaatatat aaagcatttt ctatgccaat tatttaaaat
    34201 atatattcta tgtattaatg tcatagaaat tttcattttt aatttacacc agtattgaat
    34261 ttaccaataa ttattgtaaa tattaatttt taaaattata ataaaaaaag ataaacagat
    34321 tttttctctt tatcttttaa tacagtttga gaaatttttt tctcacttaa tgagaagttt
    34381 ttttctcact taatattata ctctgatatt ttattggtta actgtcttct actaatctcc
    34441 aattttttag ctgtatttga aatattattt ccacacaaag ataaaacttt ttcaatatac
    34501 tcacattcaa actcttttct tatttctctt aaaggtctaa tacttatttt atcatctatg
    34561 tatacattat ttgatattaa atttaaattg tcttttgata aattgccttc ttcacttaaa
    34621 actacaagtc tatttattat attttttaat tctcttatat ttcctggata attgtaattt
    34681 aataaaaaat cctttacttc cttatcaatc gagtgtatct ttttatcatg ttcaatttgg
    34741 tacttattta agaaaaattc tataagagta gttaagtctt ctcttctctt tcttagtggt
    34801 ggtatagtta ttgttattgt acttattcta taaaaaaaat cttctcttat atttccattt
    34861 gatatttcca cttttggttc tttattcata gcacaaatta acctaaagtc aactttaata
    34921 gatttattac ttcctatcct ctctatagat ttgtcctcaa gtgtcctcaa aagttttacc
    34981 tgaacattta gaggtatatc tcctatttca tccaaaaata gagttccttt attcgaaagt
    35041 tcaaatctac cttttctact atctactgct cctgtaaaag aacctttttc atgaccaaac
    35101 aactcagact ccaatagatt ttctgaaaaa gaacaacaat ttacaggtac aaatatctca
    35161 ttctttcttg gacttatact atgtatatat ctagctaata tatcttttcc tacaccagat
    35221 tcccccaaga ttaatatatt aacatcttta caagcagctt tttttgctat ttttatgata
    35281 ttattaaaat ctctattttt agattccaaa gtaaattcaa aattattttt ttgtacagaa
    35341 acagatattt tacttgcctt taccttttca acttcttcta ataaattttc aatgggatta
    35401 ctttttataa aataagataa agctcctctt ttcatagcat caactgcatt ttcaatactt
    35461 ccatatcctg taactaatat aacctctata tctctattaa tagatttaat tctatctaat
    35521 agctgtactc catccatatt tttcatcata acatcagata aaaccaaatc ataattttta
    35581 tcttttttaa ttatatttat agcttcttca ccacttagtg ctatatctac aagatagccc
    35641 ttcttttgta gaattttttt cattaccact ccatattcta gctcatcatc aactaatagt
    35701 attttcatta tatagtcacc tctttattta atggaatttt tatatgaaaa caagttccaa
    35761 cccccaattt actttcaaca cttatatctc cattattctt tttaatctca ttataagtaa
    35821 tatataaacc taaaccagtt ccctcaccaa ttggttttgt tgtatagaag ggattaaata
    35881 tgtcctttag ggcatcttct tttattcctt caccattatc tttaaaatct ataaataaac
    35941 aatgattttt ttcataacag tatataataa tttttccatc ttgatgtatt gcatctattg
    36001 aattagaaat taaatttata aatacatgtt ttaacgattc tccatttata tagcatacta
    36061 aattatgttc acagtcaatt tttatttcaa cattctttaa ctgtaacatt ttatattgaa
    36121 gtttcactat attttcaata aaatttctta tatttatatg ttctaaatta tcatctgata
    36181 ttcttgcgaa atttaacaag ttggttatta tattacttgc cctatctaca ttactttcta
    36241 ttgatttaac acaatcattc acttcttcca ttgtaacgtt atcttttaat agatagcaat
    36301 tatttcttat tatacccaaa ggatttctta tctcatgtgc taccccagaa gctaattgtc
    36361 ctatagatat cattttgttt tctctaagta atttcgcctc tactattttt tcattagtta
    36421 tatctttaat aagaactact atatactcag tattattttt tttatactct acaggaaaag
    36481 tgtttatctt taaaatttta ttgtatattt ctatttcact agttttatta gtattttcag
    36541 agaaggtatt tttaataaca ccttttatca tgctaatcaa atctgctatc ttataactca
    36601 tttcacccat aaagtcatat agtactttgt tcgattctac tatattgtta ttttcatcta
    36661 caagcattat tatatctgta atactattaa aagttgcctc taaagttttt ttattttcta
    36721 ttacctgttc tgttttcctt ttgatttcta tctttaacaa atatgtatag ctataaaaaa
    36781 cataaattga tattaaaatt atacctataa aaagataaat actaggcaca attcctcgct
    36841 catacaatat atcatcaact tcattatacg tagaatacca ttttttcttt aaatctttat
    36901 acactccatt tttctgaagt ttaaaaatgc ctttatttaa aatactaacc agctcttcat
    36961 attgtttagg tacagcaaga actgcttttt tagtatatat aggattactt aaaacactgt
    37021 atttatttga aagtccataa ttatttatat agtatcgcaa tactggttca tcaccaacaa
    37081 ctgcgtctac ttttccagac attaaatggt tgactccagt ctttatatct ggagtcaata
    37141 aaatgtttat atcttgaatt ttttgcttta aaaaatttat agaataatca ccttctggaa
    37201 ttgctactgt tttccccttt aaatccatgt aactatttat atcttgggac tttttatctt
    37261 tcaatatatt tgcactcaaa gtgtatattg ggtcagtaaa tataaattta tttgcccttt
    37321 cttttgatgg aatcaagtca aaaaacttta tactatcatc tattgaattt acgaaagatt
    37381 ctttccacca attatttggt ttaaaataaa aatctctacc aatttgaatt gacagagaat
    37441 ttattaaatc aacaataatt cccttatact gtccatcttc cttaccctta tatctcaaag
    37501 gaggtgaact ttggtcagag ctgtaaatca aattcttgtg tttttctaac cacttttttt
    37561 cttcttctgt aaatggaagt gacttcttaa tatattcaaa tacatttaaa ttatactcca
    37621 tatttacata catatttgta agtgaaaata ctactaaaaa tgaataaata atccctataa
    37681 taacaatctt ttttttattc actttaaaac tccaatcttc ttttttacta taataaattc
    37741 aatatttaat aacaaaatcc tacttttttc attaaatatt tatatttatt ataaaactaa
    37801 ttgaatagat gttgaaatta tagtcattac tattcctatc aatgcttcat atggaattaa
    37861 cttaaatctt tcacctatat ccatgtttat actacctgaa ctagtatgaa atagtgagcc
    37921 atgtggtaat tgctcgaata cactagaccc agcatttact attgatgcac ctgaaatcgg
    37981 tgatagccca ccatttatta tagcatcatg aaaagtagat gatgctatag tagcaccagc
    38041 tgttgatgat gctgttgcta atgacataag tatacccgaa actggtgcca ataaaaattg
    38101 tggcatattt aaaaattgta aagcacctat tgtactctgt tgtaattcag acatctgtat
    38161 aattcctgcg atagtccctg ttccaagtaa taatatgcat accccttgca tcttagataa
    38221 tccaaaagct aaatattctc ttgaattgtt caagtttcct gtgacaatta gagttacgat
    38281 tcctcctatt ggaagggcta tcattgggtc tataactata ggagatacat ttcctaaaaa
    38341 caatagaaat atagctataa ttggaccaca taatgattta aataaacttg gtaaatcttc
    38401 tctttgctct aaaatttcat atgattgtac tttatttcct ttatttatta atatacttgc
    38461 taaaataact gtaataacaa ctccaataat tgctggaatt atatttgcca tcataacact
    38521 agagagattg acagaaaaat tatctgctac tgctatagta tttggatttg gtgatattat
    38581 attacctgct ttaccccctc ccaacatagc taatagtatt gacaatttag aataatttaa
    38641 ttttctacct atatataatc ctataggtgc tacagttatt atagatacat ccaaatttac
    38701 gcctactcca gcaagtacca tagttgaaat ggcaatcgaa aataaagccc tcttttcacc
    38761 aaatattttt acaatctgtt ctgatatttt atctactgct cctgttttta ttaaacttcc
    38821 agctaataca cctgatgcca aagctctaag aattgatggt gatatattca tagctccatt
    38881 tgccataaaa tctacagttt gtgttatatt tgctcctcca actaatcctc caataaatgc
    38941 tcctaacatt aaactatata cagcttgaaa tttttttata attaaaataa ttgctattaa
    39001 taaaccaaat atagctccaa aagtcgttat ttgcataatg tcccctccta tcataaatta
    39061 actatctttt gcttaatttt atttaaatat attttaagta ttctgtatcc actttgtcaa
    39121 ttatatttta atttatttaa ttatattgaa catagttttt tcaaaaccta attctatatg
    39181 ttataataat ttcatactac ataatcattt tacttgatta ttttaagtta atatttttta
    39241 aattaaaaag agaggatatt tatatgaatg atttaaattt aggggaaaaa atagctgaag
    39301 ttcgaaaaaa acaaaactta agtattcgag atttagcaaa actagctgat gttacaccat
    39361 cattattgag ccaaatagaa cgaggtcttg ctaatccatc tgtaaattca ttaaaatcta
    39421 tagcctcttc tctaaacgtt cctttattta cattttttgt atctgaagta gataaaaaaa
    39481 acttgatagt aagacatgat aatagaaaaa aagttatttt acctggaagc aaagaagtta
    39541 tatatgagat tttaattcca gactctagtg gtaatttaga atttgcaatt atggatttag
    39601 ctccaaatac ttcttcttgt attgatagga ttactcataa tggagatgaa attgcatatg
    39661 ttttggaggg agaagttaaa ctttttatgg atgatgatga atttactttg tccaaaggag
    39721 atagtgtaaa agttccttta ggaacaaagc ataaatggca aaatgactca aatagtgaaa
    39781 gtaaagtaat ttttgcagtc atcttgtaaa ggagtaaaaa ccatgaagac atataaattt
    39841 atattttttg atgcagatga tactttattt gattttaaga aaagtgaatc acatgctttt
    39901 aaaaaacttc tatctgagtt tgatttagaa tttaattttg agaattatat agagtcatat
    39961 agaaatataa gtgataagct ttggctcgac cttgaaaaaa atattataac tttgaatgaa
    40021 cttaaattac ttagatttga actttttgca aataaaatat ctttggatgt tgattctgaa
    40081 actcttagca aaatgtactt aaatttttta ggtgaatgta catttttaat tccaggtgca
    40141 atcgatatat tacaatatct taaaaaaaag tatactattg ttataataac aaatggaatt
    40201 tctgcagttc aaaagaaaag acttgaaaat tcaaaaataa aaggatatat tgatggaatg
    40261 gttgtatctg aagagttgaa aatatcaaaa ccaaatcctg aaatatttaa atacgctctc
    40321 aaaaagttta attgtcatga taaatcttct gccttaatga ttgggaatag cttaacctct
    40381 gatgtcttag gtggaataaa ttcaggaata gatacttgtt ggttaaattc caataacagt
    40441 ataaattata ctaatcatat accaacttat gaaataaata cacttattga attaaagaaa
    40501 ctactatagt ttgtaagtct gttcaaatta aatagaatat tactttgcaa taattttttt
    40561 agtttataca taaaatgacc aaaaaaatta ttgcaattca tacacaaaac aaatcttagt
    40621 cttgaaaact agttaaaagc attttctagg acatttgcta catcttgatt ctaaattttc
    40681 ttcatctccc attaaaataa gcattgcaac actttttatg ggggatagtt gatgataatc
    40741 attgatttct atttctatac tattatattt attttttaca tagttataaa tatccttttg
    40801 tctctctact tcaaaatctt tatctcctgg atatatttca tgcgatattt taagactatc
    40861 atactttcct tttaaataca tttttatttt ctcattaata taatctaaac atactatacc
    40921 tattttatcc aatgctatcc ctgccatcat attgcaattt tccatatagt cattcatctt
    40981 aatatcaatt ttatccccta ttgtatatag tacagcaaat gcttttttac attctttagg
    41041 tgttttatta atatcaactt cacttatata tatcttgata tctaaaatat catttatatt
    41101 tcttatttct ctttcaacga tttcactaat tgtatctgga gcttttctat ttccataccc
    41161 caaaaacttt agcacaatat tcttatctat aaaaatatcc tctaaattta tatcctttaa
    41221 aagatattta tttttattac tattataatt catcaatatc aatcctatct aattctttat
    41281 aattaattct tcctgctttt atagctgctt gtaaattttc tactggagtg gtatttaagc
    41341 agttacagcc aaaatcacat aaaaagttat catatcctct catcttcttt aacaatttta
    41401 gtgtctctct tctaatctta tctggcttag aacgtccaag aagttttatt gggtctaaat
    41461 taccaatcaa cactatatct ctaggaatca ttggagcaat ttcttcatag tctaaaattt
    41521 ggtctaaact tactgcatct atattacaac ttagcatatt atctaataat tctctggtgt
    41581 ctccacatat atgcatacct ttccaacaat caagttcatt gtagatttta tttaaatttt
    41641 ttactatata ttcatcaaat ctatctttac ttagggttac tgacgttggc tctgctattg
    41701 aaatatattt tgctcctgct ttatttgcag ctacagcata tcttcttacc aattcagttg
    41761 taaattccaa caattcttct acaaattttt tatcagttat tatacatctt aaaagttgag
    41821 tagctccagc taattgacct gcaagtgtaa atggaccttg tatcgattca tatagtggtt
    41881 ttttaatact ttttgatata actgataagc tctctatatt gagtggcata cgtccactcg
    41941 tataagggtc tggaacatct aattttctta atttatctct gtcagttata gtatgtgtca
    42001 atacacttgg aaaatcataa tctggtctta atgtctctaa acccagagtt tcacaaaatg
    42061 taatcccatc acagaatgag tatataaaat ctgattcaaa atacttgtcc atagtctttg
    42121 ctaattctaa ttgcaaatct acactatcat atacttcata tgccttttta tttattaaga
    42181 acaatccatt tgtacccata tcaggcagaa aaaaacctct atcttcacta tttatatact
    42241 gaagtaaagt catatctgaa aacatttaaa cttcacctcc tataagtttg tttattaatt
    42301 taactgcttt tggagcattt gaactgtatc catctgctcc tatttcttct gcaaactcca
    42361 tacttacagg tcctccacca attattactt ttggtctttt atctatctca atcatattaa
    42421 gctcgtctat aaccgatttc atattttcca ttgtagttgt catcattgaa gataagccta
    42481 ttatatctac attgtttttt atagcttctt ctattatatc ttcacttttt ctatttacac
    42541 ctaagtcaat aaccttatat ccagtggctt ctaccattac ttttacaata ttttttccta
    42601 tctcatgagt atctccttct actacagaca tcagaattac tccctttgat tttttcttta
    42661 cttttccagt tcccttcaaa agattaatac ctttatttaa tgcatctgtg catactataa
    42721 cttctgaaag atagtattcc ttattctcaa acttatctaa agctcctatc atacctttgt
    42781 ttaaaccata ttcataaata tcttccacat caatattttt atctatagca atttttacta
    42841 aattctctat attatctaca cccatattta atatacattc tgctatatca tcaagtatgt
    42901 ccatataata ctcatccttt ctaattactt acaaaattgc tttttcaata tccaataatt
    42961 tctcttattt aacaaggact aactctaggt atcaatcaat tttatttaat atcatctaaa
    43021 actattgata atttaaattt gcagtccatg gaaaatctac aggaaatgcc tttgtagcaa
    43081 attcatatat attttttaga tgtttaaatt cattatactg ttcctcattt ttttcaaaaa
    43141 acagtttatt aagcttatcc aaattttcta ttacaagttc ttcttctttg tatttaataa
    43201 tatatttatt ttcaacttgt ttaaattcca tgtattttag taattcaaaa tctacatatt
    43261 gactaaaata acttcttaaa ctatcacaca acttagtaaa atttattatt ttcatagttc
    43321 cttgttgata gtccaaagat tctgtcccat tacatttcaa ctggtcttta agatttttca
    43381 catgtacttt ataatttaaa tattctaatc caaatttatt tgcaacatat ttcaatatat
    43441 tttcaacatt tacagagttt aaccctattt cagcaacttc tcctacagta gaatcttctt
    43501 tttttattgt tcttattatc aaatatccta ttatattatt attttccttt ataaatacct
    43561 tcttgtaacc aattggtccc caggcaatag ttgctgcatg caatagtttt tgaaactcat
    43621 ctctcgttct tataaatcta gtactatttt gattatatag ttcaagcatt ttatctaaat
    43681 catcatcttt ttcaaaatta gtttcatcaa attcaactat ttcatatgct atttttacat
    43741 cttcaggttt tattgtatat ttataaaaac tctttaccaa actacaattt cttctactgt
    43801 atagacttct tgttcctgat ataattacaa tatctacacc atcataaaac attttttctt
    43861 ctactttatc caatatctta gatgaatagc ctctcttttc ataatctgga tgagtacata
    43921 ctccacctat agctgcaacc ttcaatctat ttccttgaat agatacatct tgaattagat
    43981 agtttacatc agaaaccact ttatcatctt ctgatattat aatcatattt tctatattat
    44041 ttttacttag taaaagagga aattcttcca tcatagttgg cttatgattt cttgatattc
    44101 taaatacata gtttattaat tctattactt tatcaaattc ttctaatttt gcacttcttg
    44161 gtcttaattc cattcatatt cctccaaata ttatttaaga tacttaaaac tctattatct
    44221 ataataaaac atttattact acagttctaa ttatatcttt tttctttaca atttttaatt
    44281 gtttttttta acaaattttt ataaaatata aacctaattt atagttaaac ttataaa
//
LOCUS       DAMJWO010000028        43751 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.029, whole genome shotgun sequence.
ACCESSION   DAMJWO010000028 DAMJWO010000000
VERSION     DAMJWO010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43751
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.029"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            108..1397
                     /locus_tag="PC366_001545"
     CDS             108..1397
                     /locus_tag="PC366_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDF2577075.1"
                     /translation="MRELLKVTLIVMLVLINAFFVACEFAMVKLRSSRIDTMITEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIVSVFNLSESIIYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLLVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRLLVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     EIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
     gene            1426..2106
                     /locus_tag="PC366_001546"
     CDS             1426..2106
                     /locus_tag="PC366_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDF2577076.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWMETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTDIYDSSVPIIDLYDEKTKNMIEFMERKGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PQNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     NSKECHNL"
     gene            2207..2746
                     /locus_tag="PC366_001547"
     CDS             2207..2746
                     /locus_tag="PC366_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HDF2577077.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKQGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFALLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSVYWTILTFIGVRYFQVYIVDSLYSLIIPYWPILVTILLVTLF
                     VDEILTIKFLRGNKDIVER"
     gene            2922..3941
                     /locus_tag="PC366_001548"
     CDS             2922..3941
                     /locus_tag="PC366_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDF2577078.1"
                     /translation="MMGKIRFGIVGTSNIANIFLRAASRVKDFELVAVYSRNLEKARE
                     FGTLHGASIFFDDLEQMAKSKDIDAVYIASPNALHSKQAITCLKHKKHVLCEKSLASN
                     LKEVKSMIKTAKDNNVLLMEAMRITCVPNFKAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKTVKAVSHILQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSHENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            4229..5419
                     /gene="dltD"
                     /locus_tag="PC366_001549"
     CDS             4229..5419
                     /gene="dltD"
                     /locus_tag="PC366_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HDF2577079.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTFPEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKRPINWSYERKKAIEDAKKRVGKNPLNIDKYYYK
                     EHFKDGIEQYKGRDKDVNLLTSKEFENYKLMLNVCTDLGINPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQKIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            5540..7054
                     /locus_tag="PC366_001550"
     CDS             5540..7054
                     /locus_tag="PC366_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HDF2577080.1"
                     /translation="MKIIEGIKKYSNTDRTALMCNGDKLSYKDLNEYSDAISVFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVIFN
                     FSDERNFGDINVIDMDKLNDIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYKELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPNLESMIFIGEALSKNLT
                     KELMSRFPNTRIINGYGPTEATVGVSVNDMTQKAIDDEKSLPVGYPMSNCKIKILDED
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNAVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGMIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            7054..8202
                     /gene="dltB"
                     /locus_tag="PC366_001551"
     CDS             7054..8202
                     /gene="dltB"
                     /locus_tag="PC366_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HDF2577081.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPAVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEVIIVKGYEYVRRKTKNKYIYWGFLFASMLPIIINKISP
                     VTSFGIIGFIGISYLNFRTIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKHISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSRIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKDKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            8221..8451
                     /gene="dltC"
                     /locus_tag="PC366_001552"
     CDS             8221..8451
                     /gene="dltC"
                     /locus_tag="PC366_001552"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HDF2577082.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            8668..9453
                     /locus_tag="PC366_001553"
     CDS             8668..9453
                     /locus_tag="PC366_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDF2577083.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNNTNLDKKQSIAKYAAKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPMSIDTMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKEYIKNSKESFVLCDSSK
                     IGIASMYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            9732..11642
                     /gene="phnW"
                     /locus_tag="PC366_001554"
     CDS             9732..11642
                     /gene="phnW"
                     /locus_tag="PC366_001554"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HDF2577084.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNLWSDKFGKVPTEDDVNELYAEFEPMLFETLE
                     EYTTPIPHVVETIEKLRKNGLKIGSTTGYTREMMNIVEPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTQ
                     EEVENMDKEELKAKMSIVSKKFKEAGAHFVIETMAELEDILIKIENETIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDVEYNNLVQDVRRRLVSLATQNTDKYTSVLMQ
                     GSGTFSVEAIIGSTISKDGKLLVIANGAYGKRMKDICNYLNIEFVDCTFKDIEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKIYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEKLSKCKGIAKSLSLDVYAQWETMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKDNGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIEKFINR"
     gene            11999..12820
                     /locus_tag="PC366_001555"
     CDS             11999..12820
                     /locus_tag="PC366_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577085.1"
                     /translation="MNEELSSLRFDGVGKCKGGIFDNVNISGTGKIEGSVKCSKFDSS
                     GSAKVFGTTECNEFFTSGLSKVEGNILASKVEISGLLRCTGNINSVEIDTSGIINVEG
                     SIKSDIIHGEGYLKANENIDCENINLSGILECNGFLNCEEVNISLNGTSNFNEVGASS
                     INIKKGHGDYCKKFRMLEKKHINFEKVSSNLISLGLLSIRKYTESKLFANIIEADEIS
                     LENSEVKVVRGKNIKIGKGCYVESLEYSESIEIDEDSIVGEIKNISEKIKLKKDK"
     gene            12861..13628
                     /locus_tag="PC366_001556"
     CDS             12861..13628
                     /locus_tag="PC366_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HDF2577086.1"
                     /translation="MEKGSIKILGEGFISSGEYENIKIVGSSKSKGNVKSNEVKVLGD
                     AKFEGDINIKNFVVNGKTIIRGNLKAERVRVNGQLNIEGDAEIDDLVITAQQKVDGKL
                     KCNNVTIRGQLSVNENMYAQDIKIYGEMRNKSNIECEDIKVYGVIKCDGLLNGENIYV
                     YSGGGSYCKEIGATNIKIGRSKDAFSLIKIINIFSGKFKCNLIEGDTIELEDASIKDI
                     RGKSISLVDNCDVGNIEYSDNLSVSDNSTVKNSIKVG"
     gene            13636..14256
                     /locus_tag="PC366_001557"
     CDS             13636..14256
                     /locus_tag="PC366_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbD family protein"
                     /protein_id="HDF2577087.1"
                     /translation="MEELISKKDLLSKTNISYGQLYRWKRKNIIPEEWFIKKSAFTGQ
                     ETFFPRDKILERIELILSMKEETSLDDIANMFMKKDINKEFDIDFILSKEVICNYTKE
                     IFQNLYKKEQSIGKKELLILSIIEKFLVKSIITFEELKLIVNIIEENFTSIYNESGKI
                     YLFRKFGVPFVVGCLDYKKVKFEKDVVKIIEIDLTKEINDISIKLS"
     gene            complement(14556..15143)
                     /locus_tag="PC366_001558"
     CDS             complement(14556..15143)
                     /locus_tag="PC366_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HDF2577088.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENISISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHIGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(15229..15666)
                     /locus_tag="PC366_001559"
     CDS             complement(15229..15666)
                     /locus_tag="PC366_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2577089.1"
                     /translation="MEDKYIVHFISKTKASMIKFIENKLSKNGLGELIPTHGNILTAL
                     YENNGILTMKEIAAKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            15770..16768
                     /locus_tag="PC366_001560"
     CDS             15770..16768
                     /locus_tag="PC366_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HDF2577090.1"
                     /translation="MNKKFKSLYITEEEGNFRRNIVEREVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVKLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKNMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKEVLLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMTGKHVGRTVVDLEKI"
     gene            complement(16888..17814)
                     /locus_tag="PC366_001561"
     CDS             complement(16888..17814)
                     /locus_tag="PC366_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HDF2577091.1"
                     /translation="MSKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMEGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSMGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTVLYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNMYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            18200..19804
                     /locus_tag="PC366_001562"
     CDS             18200..19804
                     /locus_tag="PC366_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2577092.1"
                     /translation="MKEKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKSVLDSASSENPILISHASGHMGAANTLGLKQLGV
                     TNETRDPEGGHIGRVEGSEEPNGYLEENAFFNVASKIKQPSSNEIFNSIEKAQNIYLS
                     YGITTAQEGLMEENQFNILKAMANQNKLKMDVVGYVNLKKSKSVLDNNREFIKKYINR
                     FKVGGYKIFLDGSPQGKTAWLSRPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAADQLIDAFEKVLNLKEQSSENNIRPVMIHAQTVRADQIDDMKVINMIPSY
                     FVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAV
                     NRITKKGIQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPL
                     TIDPMKIKDIKVLQTIREGEVLYSLK"
     gene            20621..21892
                     /gene="serS"
                     /locus_tag="PC366_001563"
     CDS             20621..21892
                     /gene="serS"
                     /locus_tag="PC366_001563"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDF2577093.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKDFNLDEVVKLDDERRKILQE
                     VEVMKHKLNTASKNIPNLIKEGKDVENEKIKLKELSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPEVPQGETDEDNVEVRTWGKTTTFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGLDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYVHTLNGSGLAIGRS
                     VAAILENYQQEDGSVVVPEVLRPYMGVSVIK"
     gene            22171..23676
                     /locus_tag="PC366_001564"
     CDS             22171..23676
                     /locus_tag="PC366_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2577094.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELIVSNNV
                     DDVGESEVIDINPNNYLKKTLINYSESTLNLYAAVESIRGQFIDPFKIPLIIYDDSWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSSNQFVCEYGITIYNIPILYKSNSIGV
                     IRGGYVLLSDLNLDTEHNNLYDIPEGAARSIKRLLKQISKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMASIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIKNYLNLQKLRYGDALKVKYLIPEKLYNLSVP
                     FNFIQPIVENAFTHGFRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDGNNIDKIKAG
                     IRSNNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPIENYKEYV"
     gene            23790..24488
                     /locus_tag="PC366_001565"
     CDS             23790..24488
                     /locus_tag="PC366_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDF2577095.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     IGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFNYFEYAQKALRLNVKDI
                     LLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSN
                     ISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIE
                     KGMTPKVYKLNTKN"
     gene            24773..25861
                     /locus_tag="PC366_001566"
     CDS             24773..25861
                     /locus_tag="PC366_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577096.1"
                     /translation="MSDKVNMKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     IGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIVSGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNISPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCRKKSTQSQE"
     gene            26100..27290
                     /locus_tag="PC366_001567"
     CDS             26100..27290
                     /locus_tag="PC366_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2577097.1"
                     /translation="MHELILISEKYKEDILDFFTDIHMHPELSFKEFRTTKAIKDLLV
                     SLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPIYEEVDIEYKSRYDGIMHAC
                     GHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAI
                     FGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMG
                     IQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEN
                     IVCEIARGYQATAKLDYLFDLPAVINSKEMYTIACKSVCDLYSEDAIVDPIPSTGGED
                     FSIFMEKAPGFFYWLGVGNKEQDCIYQWHNPKFKADKNSILVGTNVLCQSVINYMDKL
                     KNKI"
     gene            27381..28883
                     /locus_tag="PC366_001568"
     CDS             27381..28883
                     /locus_tag="PC366_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HDF2577098.1"
                     /translation="MRALNVVERAGNKLPDPVTIFLLLCIIVVILSAVISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDPSYQGNPAMNLYFAFISAIVLTFAGAF
                     VTEKFIAPRFTKYNDSTNDKDIQELSELENKGIKYALLSLLVVVVVIVALCIGDNAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGKVSKKIKSDKDLVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKLLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEIIILLLFMGIGIPLGPGGGISYVL"
     gene            28955..30211
                     /locus_tag="PC366_001569"
     CDS             28955..30211
                     /locus_tag="PC366_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDF2577099.1"
                     /translation="MLKTTKISDPELYKIVADELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSAVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIVLCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLST
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            30383..33157
                     /locus_tag="PC366_001570"
     CDS             30383..33157
                     /locus_tag="PC366_001570"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HDF2577100.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAQALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGVIATLLCMFMIIQM
                     QRKGMLILDTSSILSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITPKVEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAMTSEGELNLIGNSRSYMKEDNLVFSGFVGIVDPLREGVK
                     DSIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFTQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRTMKN
                     SRSMNSNSKN"
     gene            complement(33222..33407)
                     /locus_tag="PC366_001571"
     CDS             complement(33222..33407)
                     /locus_tag="PC366_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDF2577101.1"
                     /translation="MFFISDIYTKSPIKFDTPLQKEVYKILQKLDIDFERVDTDEAIT
                     MEDCVQINKKLNMKMVI"
     gene            33779..34957
                     /locus_tag="PC366_001572"
     CDS             33779..34957
                     /locus_tag="PC366_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF2577102.1"
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMFTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILLIVSIMIKIWLSRFNKFVGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKDMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI
                     "
     regulatory      35083..35168
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            35281..38235
                     /locus_tag="PC366_001573"
     CDS             35281..38235
                     /locus_tag="PC366_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HDF2577103.1"
                     /translation="MKKGNKKALLISLIMILSMVVSTIYPTVSYASELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEDNSTDNKKPEQTSEEDKSTDN
                     KKPEQTPEGEKPIDNKKPEQTPEGEKSIDNKKPEQIPEEDKSTDNKKSEQALEDEKPL
                     DNKNTEKTPEEDNLLEDENLLKVLEEELNEDYGFVVKINNNTIETESMKKISFNLTYT
                     PTSKGIQAGDSITFKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSVMQGK
                     IGLEAYVKKVDEDTNAKIHIETTGKIESGSGDIDVEIKPGDKTDVPDAKGTLKKLVEG
                     RKSTTVFMPVKNKDINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEV
                     SDFNIEQSKNSISVNFGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQED
                     DATVSIFDRGDNYLLTKGHSGATNITQVGQVINYQISINDDKSPISNVVITDNIPEGM
                     RLTTSGEDGHDFRVVEVPMNGSWTPWSKEKIANNISYKVEEKRNESGQVDKVITGFTI
                     NLSKEEVESKFFIAYTLKVISIEDSYINRAVLDANNSEIDKNDEINFKKNSGLISAKK
                     EVDKKVLNSSDNQIVKYKINMSTYGVYDAGQVNLLDEVNPSLKISNIKYSDNLELKKE
                     AGDGKNTIRLVNKYEFKQIKEGEPVQSWVTFDADFTNVKVGETIQNVAQINGSSPPGV
                     ETTKQGYAFEAKKVDALDKNVLSGAKFNLEDAFGNIVVKDLVSDEDGVIQSSVKKPGI
                     YYLVEVMAPSGYEKLKDKIKVEIGNKDIGRIVDIGNIENIRQENPPVNPPVPPNTDEP
                     IVNPPVPPSTDKPRKPSNPSDTEDTIVINPPVPPSEDIINPPIPEILNPPVPPSEEVI
                     ETPVKQIVPIPEVVKPSVSEEKNNKAKDDTLVNPPVPPKTGDSTTIIGEILLVIGAIV
                     GLVVLRRNKNTN"
     regulatory      38421..38506
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            38606..39268
                     /gene="zmp1"
                     /locus_tag="PC366_001574"
     CDS             38606..39268
                     /gene="zmp1"
                     /locus_tag="PC366_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HDF2577104.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHAYSTTIQQNKDTLSQIVVF
                     PTGNYNKNEANAMVNRLANIDGKYLNVLKQDNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYPEEFFAEAFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     gene            complement(39386..40348)
                     /locus_tag="PC366_001575"
     CDS             complement(39386..40348)
                     /locus_tag="PC366_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDF2577105.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHIFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVLSPILALL
                     ILKEIIPINMVIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(40518..41708)
                     /locus_tag="PC366_001576"
     CDS             complement(40518..41708)
                     /locus_tag="PC366_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2577106.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVA
                     NRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPNGTFYLF
                     PKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKL
                     YNLK"
     gene            42014..42460
                     /locus_tag="PC366_001577"
     CDS             42014..42460
                     /locus_tag="PC366_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2577107.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNHIKKEFSDTEYKELVKNLHVVKDIKTAVEEG"
     gene            42462..43556
                     /locus_tag="PC366_001578"
     CDS             42462..43556
                     /locus_tag="PC366_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="HDF2577108.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKS
                     GVALITLGDVSIRPSFHKVAISLSDEDGVIKYKKIVDEIHNSGAKVSAQLFCSDYDVN
                     LIKDTMKMGITSHDEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLVGSFSSSIFNNRNDEYGGTCDNRSRFASEIISSIRDEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLLSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKDEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADSNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTRSQFGCILD"
     gene            43644..>43751
                     /locus_tag="PC366_001579"
     CDS             43644..>43751
                     /locus_tag="PC366_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF2577109.1"
                     /translation="MKSLVLYSSLTGNTKKIAYAIYDEIQEEKDIKDVNE"
BASE COUNT        17322 a         4760 c         7511 g        14158 t
ORIGIN      
        1 atatattaat aaatatgata gaatatatat tataaattaa atttataaat ataagggggg
       61 aactttgagt tcttatagat ttcttacatt ataagaacca atactttatg cgggagttat
      121 taaaagtaac acttatagta atgcttgttt tgataaatgc tttttttgta gcttgtgaat
      181 ttgctatggt aaaacttcgt agttctagga ttgataccat gataactgaa ggtaataata
      241 atgcaaaaag atgtaaaata ataaaagaca acttaaattc ctatctttct gcatgtcaac
      301 ttggtataac actttgttca cttgcattag gttggatggg agaatctaca gttaaagagt
      361 taattttacc aatagtaagt gtatttaatc ttagtgaaag tattatatat actatatcaa
      421 tttccatttc ttttttaatt ataacaatga tggaggttgt aataggagag ttggttccta
      481 aagctttagc actttataat acagaaaaaa taatgttgag tacatctttt ttattagtag
      541 gattttataa gttaacatat ccaataatat attttttcaa cttaagtact gatttatttc
      601 ttaaaccatt tggatattca caagctgatg aggttgatga accccataca ggtgacgaaa
      661 taagactatt agtagaagaa agttataaaa gtggacttat agatgaatca gagcaaagat
      721 tagttgataa tatttttgaa tttgaagaaa agaaaattag agagataatg gttcctagaa
      781 ctgatatggt atgtatatat gaaagtgatt ctgaagaaaa gatattagct attttaaaag
      841 aggaaggtgt tacaagatat ccagtatgca gaaaaaataa agatgatata ttaggttttg
      901 tacatataag agatttatac aatcaaaaga taaatgaaaa taaaattgaa ctagaagaaa
      961 tattgagaga tattatatat atatctgaaa atttaactat agataaagct cttgagagaa
     1021 taagaaagga aaaacttcaa cttgctatag ttgtggatga atatggtggt acatctggtg
     1081 tggtaacaat agaagatata ctagaagaga tagttggaga aattcaagat gaatttgaca
     1141 aagaagagac tcatattaag aaaataggag caggttctta cttagttgat ggaactgaat
     1201 ctatcaacta tattaataag tattttggac ttgatataga gcatgatgga tttgacagta
     1261 taggtgggtg gatatcctat atgcttggtt caaatattaa agtaaaccaa agcgtaactt
     1321 ttgaaaatta caattttaca atattagaat tggataaatt gagggttgta aaattaatca
     1381 taaaaagtgt aatataatta tatcaaaaaa tattggagga attgtatgca aaaagtagaa
     1441 ggaattattt ttgacatgga tggagttttg tttgactcag agagaatttc tcttgaattt
     1501 tggatggaga cgtttgaaaa gtatggatat actatgacta aggaaattta tacatcagtt
     1561 atgggaagaa atcgtaaagg aataatagaa ggtcttacag atatatacga tagttctgta
     1621 ccaataatag atttatatga cgaaaaaact aaaaatatga ttgaatttat ggagaggaag
     1681 ggagctccta tcaaattagg agtcaatgaa ctaatctctt ttttaaagga aaatggatac
     1741 aaaatggctg ttgcaacatc aacaaagaga gaaagagcag taaagagatt agctaaggca
     1801 aatttaaaag attactttga tgctatagtt tgtggagatg atgttgtaaa ctctaaacca
     1861 aaccctgaga tattcttaaa agcagctaaa aagataaatg ttaatcccca aaattgtatt
     1921 gtcatagagg attcgcctat gggagttgaa gctgcataca atggtgggat aagatgtata
     1981 aatgtaccag atttaaaaga gccagatgag caaattaaat cacaatcaca taagatactt
     2041 gaaaatttac tggaagttag agaataccta aaaagtttga actctaaaga atgtcacaat
     2101 ctataatata aagtattaat taaataaatt aaatataatt tctttgattt agaataaatc
     2161 catgaatatg agaaaaaata agtataaaca gctaggagga atattcatgg ataatgtagg
     2221 ttctctatta tattttttat ttaatttttt cttgtatggt tttataggtt ggataattga
     2281 aaacttatat agttattata aacaagggca ttttcaagaa gatggatttt taaatggtcc
     2341 atttaaacca atgtatgcaa ttgcaatgtc gattataata gaggtctcaa gatttattga
     2401 ccccaataat atatttgcat tgcttttatt atgtctagta gtgccgacag tagtagaata
     2461 tattacagga atacttatga aagtatattt taataaggtc tattgggatt attcagatta
     2521 taagtacaat agtagaggaa tagtatgtct aaagttttct gtatattgga ctatattgac
     2581 atttattgga gttagatatt ttcaagtgta tatagttgat agtttatata gtcttataat
     2641 accttattgg ccaattcttg taactatact tttagtaaca ttgtttgtgg atgaaattct
     2701 tactataaaa tttttgaggg gaaataaaga tatagtagaa agataacttt aaaaatataa
     2761 gttgaattta gattgtagtt aaaagaaagc tatgttaaaa tggtgaaatc atttaaaatt
     2821 agctttcttt tttatttgat aaaattattt tataatatat ctataagttg taaagttttt
     2881 tattaaaatt aaaataaagt gtagaaaatg gggagtgatt tatgatgggt aaaataagat
     2941 ttggtattgt tgggacaagc aatatagcaa atatatttct aagagctgca tctagggtta
     3001 aagattttga attggttgct gtatattcta gaaatttaga aaaagctaga gaatttggaa
     3061 ctctacatgg agcaagtatt ttttttgatg atttagaaca aatggctaaa tcgaaggata
     3121 tagatgctgt atatatagct tctccaaatg cattacattc aaagcaagcc attacttgtt
     3181 taaaacacaa aaaacatgtg ctttgtgaaa agtcgttagc atctaattta aaagaagtca
     3241 aatcaatgat aaaaacagcc aaagataata atgtattgct tatggaagct atgagaatta
     3301 catgtgttcc aaactttaaa gcagttaaag aaaacttgta taaaataggg aaaataagaa
     3361 gattttttgg aagctattgt cagtattctt caagatatga taaatataaa aatggaatta
     3421 tagaaaatgc ctttaaaaaa gagttgtcaa atggagcttt aatggatata ggagtgtatt
     3481 gtatacatcc tatggtgaat ttatttggtg ctccaaaaac tgtaaaggca gtttctcata
     3541 tacttcaaac tggagtggat ggagaaggtt cagctgtatt tcaatatgat gatatggatg
     3601 caataattca gtattctaaa gtagctgatt cttatatacc atctgaaata caaggagaag
     3661 agggaagtat aataattgaa aagcttaatc tatttgaaaa agctattatt aaatacagag
     3721 atggaagaga agaagatata tctattccaa aagaaaaagc agaggaaaag cctagagaaa
     3781 tagaaggaat gtattatgaa cttgtagagt ttataagtct tataaataac aataaaatag
     3841 aatcaaatat aaattctcat gaaaattcaa taatagtaat ggaaattatg gatgagataa
     3901 gaagacaaag tagtattgtt tatccagctg atagtatata gcttatatta gaaaatataa
     3961 gaatttataa tatatattct taaataaatt taattttaag ttaaggtaag gtgtatactt
     4021 agccaagtgt taaaatgtca aattataagt atgaaaaagt gctaaaaaga aatttatttt
     4081 tggtgttttt ttcttttttt ttacaatttt gtaacagtat caaaaaaagt tttgacgatt
     4141 ttattacaat tttgtagttg aatatacata tcaaaactaa tatgattaat aataacataa
     4201 atttgaatat ttttagagga gagaaaatat gagaaaattg atatacttta ttacaccttt
     4261 tataataggc gtagtatttt tatttgggtt agacaaattt cttgattcta aaactgatga
     4321 acttttgagg gagaaaaatc tacttccaat tatggatgat actttaagtg atataaaaga
     4381 taaaggggtt acagcaaata atcatttttt aagagaaaag gatattatga ttttggggtc
     4441 atcagaactt agtaattcaa caaaacaaca tccaaagtac tattttaata caaataggag
     4501 taaaaataag gtgtttgcaa ttgggagagc ctatactcag acattacaag atgctgcaat
     4561 attaggaagt atgaatccta atattgataa taagaaagtt gtcttgttaa tttctatgca
     4621 atggtttatg gaaaaagacg gagtcacaag tcaccattat cagtctagat tttcaccaat
     4681 acaattttat cgatttttag ataatccaaa aatatctaaa caaaataaga ttgaatatgc
     4741 aaaaaaatca agtaagctat tatggggaag tgatgagtat aaagcagaag cattatatgc
     4801 taagctatat gaacctaaga catttcctga aaaagctgaa aaggtgcttt tagagcctta
     4861 ttttcaagga agaaagtact gtatagctct taaagaaaag ggtattcttt ataaacgatt
     4921 aattaagcta gataaaaaga gagcaacaaa aagaaaaaga ccaataaatt ggtcatatga
     4981 gagaaagaaa gccattgaag atgctaaaaa aagagttggt aaaaatccac taaatattga
     5041 taagtactat tataaagagc attttaaaga tggtatagag caatacaaag gaagagacaa
     5101 agatgtaaat ttattaacat ctaaggagtt tgaaaattat aaactgatgc taaatgtatg
     5161 tactgactta ggtattaatc cagttgttgt attaatccca agtatggata aattctataa
     5221 tttgactggt atttctgaaa aagaaagaaa tcagtactac gataaagcac aaaaaatagc
     5281 agaaagcaaa ggctttgaag ttctaaacct taaagataaa gggtcagata agtattattt
     5341 aagggatgta atgcatcttg gtacgaaagg atgggtagat gtctgtgaga gattatttaa
     5401 aatatttaaa gaacaataaa gatttgttaa ctagtatttg tttaactatg gttataatat
     5461 tggcgatagg agttctaaca tttactccat ttaaagaatt gccatttatt tataacggat
     5521 tttaaaggag cattcttata tgaaaattat tgaaggaata aaaaaatatt caaatacaga
     5581 tagaacagca ctaatgtgta atggagataa actttcttat aaagatttaa atgaatattc
     5641 agatgctata tcagtatttc taaaggatgt atacaaagaa gaggatactc ctatagtaat
     5701 ttatggaaat aaagaaaaca tgataatggc atgtatgata ggagctttaa aatcaggtag
     5761 agcgtatgtg cctcttgata ttagttttcc aattgataga gtttttgaag tcactaaaga
     5821 gataaaacca aaagtaatat ttaattttag tgatgaaaga aattttggag atatcaatgt
     5881 aattgatatg gataaattaa atgatataat aaatgaatat cagggaaaat cattagataa
     5941 agaaaactgg gtaaaagatg atgaaaatgc atatatacta tttacttcag gaagtacagg
     6001 aaagccaaaa ggggttcaaa taagttcaaa caatttagat agcttttcag attggataag
     6061 cccatatcta aacatagatg gaagtgaaaa agtaataatg aaccaaccag catattcttt
     6121 tgacctttca gttacaacaa tataccctgg tcttatccat ggagctacat tattttcaat
     6181 atcaaaagat gtattagcag actataaaga actatttaga caatttagta tctcagatat
     6241 agctgtatgg gtgtcaactc cttcttttgc aggagtatgt ataactgaaa aagagtttaa
     6301 tagtaaaatg cttcctaacc ttgagtcaat gatattcata ggagaagcac tttcaaaaaa
     6361 tcttactaaa gaacttatga gtagatttcc aaacacaaga attatcaatg gatatggacc
     6421 aaccgaggct actgttggtg taagtgtaaa tgatatgact caaaaagcta tagatgatga
     6481 aaaaagtctt ccagttggat accctatgtc aaattgtaaa ataaaaatac ttgatgaaga
     6541 tggaaatgaa cttaaagaaa atgaaaaggg tgaaattata ataattggac catcagtttc
     6601 taaaggttac ttcaataata aagaaaagac tgatgaagta tttttctatg atgaaataga
     6661 tggtgtaaag tggagagctt ataaaactgg agatatggga tatcttttag atggaaatat
     6721 atattattgt ggaagaaaag attttcagat taaattaaat ggatttagaa ttgaaataga
     6781 agatatagaa aataatttga gaaaagtaca taatgtaaaa aatgcagtag ttttaccagt
     6841 atataaggac gaaaaaattg cttacttaaa aggtattgtt gagttaaatg aaaagaatga
     6901 tttaagtaat attaaaaatg ggatgataat aaaaaaggaa cttggaaagt atataccttc
     6961 atatatgatt ccaagaaata tttcaataat ctctgagttt ccaacaaata tcaatggtaa
     7021 aatagacaga aagaaactta tggaggaaat ttaatgattt tttcacagta tggagattat
     7081 ttttatcttt atatattatt attaacatca ataccagcag taattttagg tctaatgggc
     7141 aagaatataa agtattatgg tatgttggca agtttgttta tgatattctt aatagtagga
     7201 attgatgtcc agctaaagta tttggtaata tttattattc ttgaagtaat aatagttaaa
     7261 ggatatgaat atgtaagaag aaaaactaaa aataaataca tatattgggg attcttgttt
     7321 gcatcaatgc tcccaataat aataaataaa atatctccag ttacttcttt tggaataatt
     7381 ggatttattg gaatatcata cttaaatttc agaactatac aaatggttat tgaaatttat
     7441 gatggagcta taaaagaagt taaaatttca aagatgcttt attttatgtt attttttcca
     7501 actttaagtt ctggacctat tgataggtca agaagatttg aacaggactt ggaaaaacac
     7561 atctctagaa aagagtatat agaagaatac ttactgccag gaataaaaaa tattgtcatg
     7621 ggagtaggtt ataagtttgt tatagcattt ttgataaata catattgggt atcaagaata
     7681 cctaaagata tgagttttat aaatatttta agttatatgt acgcatatag tttatacctg
     7741 ttctttgatt ttgcaggata tagtttattt gctataggta cagggtacat atttggaata
     7801 caagtaccta taaactttga caagccattt atcagtaaag atatgaaaga gttctggaca
     7861 agatggcata taagtctttc aagatggttt ggagattata ttttttctag atttgttatg
     7921 tcatcaatga gaaagaaaag atttaagaaa aggactactg ctgctcatgt ggctcagatg
     7981 ataaccatga taacaatggg attttggcat ggtctaactt ggtattatgt tgcttatggt
     8041 gtataccaag gattggcact tgtgttaact gatatatatc agcgaaaatc taaattttat
     8101 aaaaaacata aaaaagataa atggttcgag agagtgcaga ttttcattac attccatatt
     8161 gtgtgttttg gattgctgat attctcaggt tatttagctt aattttaagg aggaaaattt
     8221 atgcaagaaa cagttataga aatatttgaa gatgtattag ggactgatga gataagagaa
     8281 gatttagacc ttaatttatt tgagacggaa cttttagact cattagctat aattgaagtt
     8341 ttacttgaaa ttgaaaatag attagggata gagcttcaac caactgattt agagagaaaa
     8401 gatatgtcta ctgtaaataa tttagtaaaa ttcttggaga caagaaaata aattagtagt
     8461 tagactttaa atattaattt ataaaataaa attttacaaa gtccatctga tactaatatt
     8521 tgatggactt ttttaatgat aatacaaagt cttttgaaaa taactttaat taagtaaaaa
     8581 atttaataca taaatatgat ttcataaatc ttaggtatca ttgtaatatt ataggagaaa
     8641 aatatattat atttaggagg aaaatgaatg tctttaaatt cgatagatag aaaaaaagaa
     8701 atacttaaat tattagattc aaaagggaag gtaaatacta aagaattagt aaaaagatta
     8761 gaagtatcat cagaaacaat aagaagatat ttggaagaat tagaaaatga aaataaatta
     8821 aaaaaggtat atggtggtgc tataaaaata aattatggag tgattgaacc agaacatata
     8881 aagagaaaca atactaacct agataaaaaa caaagtattg ctaaatacgc agctaagttt
     8941 gtaaatgaca atgagtcaat tatcatagat gaaggtacta ccaatttgca gattgtagat
     9001 tatataatat ctgtaaacaa tttaaaaatt attacaaact cttatccagt tctatcaaaa
     9061 ttgatttctt atgagaatca aggtttgttt gatggagaag ttatatttat tggtggaaaa
     9121 gtaaatttaa aacaccaaag gacagcatgt ccaatgtcaa tagacactat gaaaaactta
     9181 tacgtagata aagcttttat atctagtgaa ggtatacttg atagttttgg aattagtagt
     9241 atagaccaaa ataaggcatt gttgtcaaaa gaatatataa aaaattcaaa ggaaagtttt
     9301 gtattatgtg atagttctaa aataggaatt gctagtatgt ataagatagc agatttagag
     9361 gaattagatt ttgttatttg tgatgtagaa cctccgaatg aatggaagga taagttaaat
     9421 gagataaata taacatggat agaagcaaaa taaaccctta gttttatata atacaactat
     9481 gcttaataca actaaattca taaaatatag tcagttcata gattaagatt agaaagtaaa
     9541 ttttagattg taacttagga ttttatggaa atatgatata aaataaaaac aattaaatac
     9601 aactaaaaac agaaatttaa tatatattta acctaaatat gatgtataat taacatatga
     9661 aagttatact ttaaaagtaa aaacaattaa aaacacaaaa attctaaaat gaatctatgg
     9721 aggctataaa tatgaaaaag atatatggag aaaaaataaa agcagtagta ttcgattggg
     9781 ctggaacaac agtagattat ggatgttttg cacctcttaa tgtatttata gagatattta
     9841 aaagaagagg tatagatgta acaatggaag aagcaagaaa acctatggga aaattaaaaa
     9901 tagaccatat aagagaaatg tgtgaaatgg atagaataaa aaatctttgg tcagataagt
     9961 ttggtaaagt gccaactgaa gatgatgtaa atgaacttta tgctgaattt gagccaatgt
    10021 tatttgagac attagaagag tatacgactc caattcctca tgttgttgaa actattgaaa
    10081 agttgagaaa aaatggatta aaaataggtt ctacaacggg ttatacaaga gagatgatga
    10141 acatagttga accaaatgca gcaaagaaag gatactcacc cgattttctt gtaacaccat
    10201 cagaagtatc tcaaggaaga ccgtatcctt ggatgtgcta taaaaatgct gaagctttag
    10261 gggtgtctcc tatgagttct atggtaaaag taggagatac aataagtgat gtaaaagaag
    10321 gcgtaaatgc aggaatgtgg agtgttgctg taataaaagg ttcaagtgag ttagggctta
    10381 cacaagaaga agtagagaac atggataagg aagaattaaa agctaagatg agtatagttt
    10441 caaagaaatt taaagaggca ggtgcacatt ttgtaataga aactatggct gagttagaag
    10501 atatactaat aaaaatagag aatgaaacta ttaaatcaga ttttgtacca gaaaatgatt
    10561 acatattact tacaccagga ccactatcta ctactaaatc agtaagagca tctatgttaa
    10621 aagattggtg tacttgggat gttgaatata ataacctagt acaagatgtt agaagaagat
    10681 tagtatctct agcaacccaa aatacagata aatacacaag tgtattaatg caaggaagtg
    10741 ggactttttc agtagaagct ataataggaa gtactatttc aaaagatggt aaacttcttg
    10801 taattgcaaa tggagcatat ggaaagagaa tgaaagatat atgtaattat cttaacatag
    10861 aatttgttga ctgcacattt aaagatatag aagcagtgga tttaaatgta gtagaaaatt
    10921 tattaaaaga aaacaaggat ataacacata tatcaatggt tcactgtgaa actactacag
    10981 gtagattaaa tcctatacaa gaggtaggga aacttgcaaa agaatataac aaaatttata
    11041 tagttgatgc tatgagtagt tttgggggaa ttgagattga tgttgaagat tttaatatag
    11101 attttttagt tagtagttct aacaaatgta tacaaggagt acctggattt ggttttataa
    11161 tagctaataa agagaaatta tctaaatgta aaggtatagc taaatcatta tctcttgatg
    11221 tgtatgcgca atgggagact atggagaaaa ataatggtaa atggagattt acttcaccta
    11281 cacatgttgt aagagctttt tatcaagctt tattagaatt ggaagaagaa ggttctgttg
    11341 aaaaaagata tgctagatat aaagaaaatc agtttacaat agcttcaaga ttaaaatctt
    11401 taggatttga tactttggtg aatgataatg ctcaatcacc tgtaataaca actttcttat
    11461 atcctaaaaa tgcaaagttt gaatttatgg aattttatac ttatttaaaa gataatggat
    11521 ttgttatcta tccaggtaaa ttgactgata tagatacatt tagaataggt agcataggtg
    11581 aagtttatcc aactgatatg gagagactag ctgatgtaat agaaaaattt atcaatagat
    11641 agaagaagat agtgtctttt aggttacaga atagtgcgga gagcctactc ctttaggtgt
    11701 gaaatgatag cacaaacagt gtataaaaag tattgacagt agaatttaaa gacttatatt
    11761 ttagaagttt atacaatgaa tatataaaga ttgagtaata gggatatatt ttatttaaac
    11821 cacaatctaa gaaattagat ttctagttta aataaagcat ttccctatta tttttatgcc
    11881 tatttataga aaataaatga tagttgcttt attaagtatt attatcagac ttgacaacgt
    11941 aacaatgttt tgttatatta ggtttaaaga taaaatacgg taaagaaagg atatcattat
    12001 gaatgaagaa ttaagttcac taagatttga tggtgttgga aaatgtaaag gtggaatttt
    12061 tgataatgtt aatatatcag gaacaggcaa aatagaagga agtgtaaaat gtagtaaatt
    12121 tgattcttct ggttcagcaa aagtttttgg gacaacagaa tgtaatgaat tttttacatc
    12181 tggtttaagt aaagtagaag gaaacatact ggcatcaaaa gttgagatat cgggacttct
    12241 tagatgtaca ggaaatatta attctgttga aattgatact agtggaatta ttaatgtaga
    12301 aggaagtata aaatcggata ttattcatgg agaaggatat ttaaaagcaa atgagaatat
    12361 agattgtgaa aatatcaatt taagtggaat cttggagtgt aatggatttt tgaattgtga
    12421 agaagttaat attagtttaa atggaacttc taattttaat gaagttggag caagtagtat
    12481 aaatataaaa aaggggcatg gagattattg caaaaaattt cgtatgctag aaaaaaagca
    12541 tatcaacttt gaaaaagtgt cttcaaattt aataagttta ggtctattat caattagaaa
    12601 gtatacagaa agtaaattgt ttgcaaatat tatagaagca gatgaaataa gcttagaaaa
    12661 tagtgaagtc aaagttgtaa gaggaaaaaa tattaaaata ggcaagggat gttatgtaga
    12721 aagtttggag tacagtgaaa gtatagagat tgatgaagat tcaatagttg gtgaaataaa
    12781 gaatataagt gaaaaaataa aattaaagaa ggataagtaa taaataggtt taaaaataaa
    12841 atttaaaatg aggtaataat atggaaaaag ggtctataaa aatacttgga gaaggcttta
    12901 taagtagtgg tgagtatgaa aatataaaaa tcgtgggaag ttctaaatca aaaggaaatg
    12961 ttaaaagtaa cgaagtaaaa gtccttggag atgcaaaatt tgaaggtgac atcaatataa
    13021 aaaattttgt tgttaacgga aaaactatta taagaggcaa tcttaaagca gagcgtgtaa
    13081 gagtgaatgg tcaacttaat atagagggag atgcagaaat agatgactta gttataactg
    13141 ctcaacagaa agtggatggc aaacttaaat gtaataatgt tacaataaga ggacaattaa
    13201 gtgtaaatga aaatatgtat gcacaagata taaaaatcta tggcgaaatg agaaataaat
    13261 caaatataga atgtgaagat ataaaggtat atggagtaat aaaatgtgat ggtcttttaa
    13321 atggagaaaa tatatatgtt tattcaggag gaggttctta ttgtaaagag ataggggcaa
    13381 ctaatataaa aataggaaga agcaaagatg ctttttcatt aattaaaatc attaatattt
    13441 tttcaggaaa gtttaaatgt aatttgatag agggagatac tattgaatta gaagatgcat
    13501 caataaaaga tatacgaggc aaaagcatat ctctagtaga taattgtgac gttggaaata
    13561 ttgaatacag tgataattta tcagtttcag ataattctac tgtaaaaaac agtataaagg
    13621 tgggctagaa aagttatgga agaattaata tctaagaaag atttattgag caaaactaat
    13681 atatcttatg gtcaattata tagatggaaa agaaaaaaca taataccaga ggaatggttt
    13741 ataaaaaaat cagcttttac aggtcaagag actttctttc caagagataa aatactagaa
    13801 agaatagagt taatattgtc tatgaaagaa gagacttctc ttgatgatat tgcaaatatg
    13861 tttatgaaaa aggatattaa taaggaattt gacattgatt ttattctcag taaagaagtt
    13921 atatgtaatt ataccaaaga aatatttcaa aatttatata aaaaagagca aagcataggt
    13981 aaaaaagaac tgcttatatt gagcataata gagaagtttt tagttaaatc tataataact
    14041 tttgaagagt taaaattgat agtgaatata atagaagaaa attttacatc aatatacaat
    14101 gaaagtggaa agatttattt gtttagaaag tttggagttc cattcgtagt aggatgtctg
    14161 gattataaaa aagtaaagtt tgaaaaagat gtagttaaga ttattgagat tgacttgaca
    14221 aaagaaataa atgatataag tataaagtta tcatagtgta ttatcttata taatgtatta
    14281 taataatcta cttaaaatac actttattta aatatttagt ttaaagataa gattttatgt
    14341 gagtatgtaa aagttaaaga tagatttaag taggttatag ggattagtaa ataataaaat
    14401 gaaccatgat gaattactat aaattgtatt taaactacat tttctactta tagtaatatc
    14461 aatggttcat tttattgtta ttaagataat acagtattta taaaaatact tgatataaat
    14521 atagtaaatt gtttaaatag aattattgcc ttagtttatt caaataatga gtttttaaaa
    14581 tctaagaaat atccttgtgg atgaagacat acaggacaag cttttggagc ttctttacct
    14641 atatgtatat ggccacaatg tgtacatatc cattgtatat cttcatttct tctgaataaa
    14701 gtaccttctt ctaaatcagt agcatatcta ccaaatctat caccatgaac tttttctatt
    14761 tcagctatat tttcaaataa cttagctata gattcaaatc cttcttcacg tgctgttttt
    14821 ccaaagtttt tatatacatc atcccactct tgaagctcat tatgttgtgc agctttaagg
    14881 tgttgtgctg tcttgtcata taaatctaca gggtatgctc ctgatatact tatattttca
    14941 ccagcaaatt cttttaattt agaaaagaat tgttttgcat gtgatttttc ttggtcagca
    15001 gtgtaattaa ataaagactc tattatatat aatccttctt tttttgctac agatgcagaa
    15061 atattgtatc tatttctagc ttgactctca cctgcaaaag ctcttaataa attttcttta
    15121 gttttactat cttttaaatt catattctac ctctctatca taataaattt ttacaatatt
    15181 tgattctttt tatttattat tccaatagga gatataatta tgctcaattt agtcagcatt
    15241 tttaaaatta tcattaattt tttttaaaat tctaagaaat tcttgttttt cattttctgt
    15301 aatattatgg tatgctgtct ctttaacttg tgttgagatg ctattaaaag tatcttctat
    15361 aagcagtgcc ttttttgtaa gctttatata cgtgatacgt ttgtcatttg tacatttttg
    15421 tctttctaaa tatcctaggt ttataagttt attaaccaac actgtaacag tggatttatc
    15481 ttttcctatt ttagctgcaa tttctttcat tgtaagtatt ccattatttt cataaagtgc
    15541 agttaaaata tttccatgag taggtattaa ctcacctaaa ccatttttac tgagtttatt
    15601 ttcaatgaat ttaatcatac tagcctttgt tttacttatg aaatgtacaa tatatttatc
    15661 ttccataaat tattctccaa tctttaatct atttaaatta gtttgacata aaactattta
    15721 taaactataa ttagtttaac ataaaactaa atgtattggg aggaaattta tgaataaaaa
    15781 atttaaatca ctatatatta cagaagaaga aggaaatttt agaagaaata tagttgaaag
    15841 agaagtagat acattgccag aaggcgaagt tctaataaaa gtaaaatatt cttctctaaa
    15901 ttacaaggat gcactttctg caaatggtaa taagggtgtt acgagaaagt atcctcatac
    15961 accaggaatt gatgcatctg gtatagtaga atctagtagt tgtgatgatt ttaaaattgg
    16021 agaagaagtt ttagtaacag gttatgactt gggaatgaat acttctggtg gtttttcaga
    16081 atacataaga gttccttcta gttgggtagt taaacttcct aaaaatcttt cactaaaaga
    16141 agcaatggat tatggtacag cagggtttac agcagcttta tctgtgtata aatttataga
    16201 ttctgtagac aagaatatgg gagatgtatt agtcactggt ggtactggag gagttgctgt
    16261 aattgcaact aaaatattga ttaaattagg ttattcagtt gtagtttcaa caggaaaatt
    16321 agaagaacaa aaagaagtat tactaaactt aggtgttaaa gatgttatac ataggtcaga
    16381 agtggatgat aactcaggaa gacctctgct tagaccaaga tgggctggag taatagatac
    16441 agtaggagga aatactctag caacagcaat aaagacaact aattattgtg gagcagtaac
    16501 aacttgtggt aatgcaggag gagttgattt tacaagttca gtatatccat ttatcttaaa
    16561 gggaattact ttatatggta tagattctgt ggattgccca atgaacttaa gattaaaaat
    16621 atgggattta ttatcaaatg aatggaaatt agatgattta gatgatatgg taaatgtagt
    16681 atcattggaa gagttaaatg atagtataga ttcgataatg acaggaaaac atgttggaag
    16741 aacagtagtt gatttagaaa aaatataggc gaataaattt ataattagga ttataggttt
    16801 taagcaaaaa tgagatactt gaaatttact tatgagtatc tcattttttt atgtaaaaaa
    16861 atttatgtag atgtttgtgt aaaaagatta ttcatgaaca attaattcaa atacatctgg
    16921 tcttgaatag tgaccttctg aatcaaaatc tagtctacta agtactattt tttctaggtc
    16981 taaatcagct attagcattt cttctttatt gaaaatagga cctgctacat attttccaaa
    17041 agggtcaact atacaacttc ctcctggaca cataatttct ggttctgcat ctagctcctt
    17101 atagtagtta aggtcagttg gatacatatt tttttcaaca tattgattgc atccaattac
    17161 aaaacatctt ccttctaaag caatatgctt catagttgct tgccactctt ctcttgaatc
    17221 tgcagtaggg gctatgtaaa gttttacacc cttagcataa agaactgttc tagctaatgg
    17281 catataattt tcccaacaaa tcaacgaacc catttttcca tatggagtat caactactgt
    17341 aagagtactt ccatctcctt ctccccaaat acatctttct gttcctgtag gtttaagttt
    17401 tctgtgttta ccaattagct taccttctgg agagaaaaat aagtttgtgc aataaagggt
    17461 acaatttata tcattaccat ctctttctgt tatacccatt gatagatata ctcctgcttc
    17521 ttgtgctgct tttcctaata aatctgttgt agcactagga actggtacag aattatcata
    17581 gtatcttttc caatcttctc taccttccat tgttctactt ccaacaacaa atccaaatga
    17641 aagacctctt ggatatgcag gtatgaatgc ttcagggaaa actacgatat ttgccccttt
    17701 tctaccagct tctttaatta atcctaatgc tttttcaaca gttttttcta aatccattat
    17761 gactggtgac gcctggacaa cagcaattct tacattttta ttttccttgc tcataaaaaa
    17821 cctcctaaaa aatatttaaa ttttttgcat tgaatagatt acatgagatg ttatttgaga
    17881 actaagatac ttatattgtg aataataatg taactgtata tttaaaataa tacatcatga
    17941 tttaaaaaat tacaattgta cagatataat tgagtttaga tatttaaatt taacaactta
    18001 taatattttt tcaattagta taaagcctat taatttgtct tatttacaat gaatagtatt
    18061 tacttcttgg caaacaataa ttaaaaataa aacttttata tgattaaact ctaaagaaaa
    18121 agtttataaa gaagataata taattaagca gaaaataatg aaaaaaattt attaaagtag
    18181 acaacgtaag gagaatttta tgaaagaaaa aatttattac aatggaaata tcatcacaat
    18241 ggaagattca atatgtggag atgctattct tataaaagat aaaataataa aaaagatagg
    18301 aacaaaagaa gaagtatttg ctttgaaaaa taaagataca gaaattatag atttacaagg
    18361 taagacattg atgccatctt ttatagattc acatagtcac ttgatagctt ttgctactac
    18421 tctaaagcta gttcctttag aagatgcaac cagttttaaa gacatagtaa aaaaaataca
    18481 ggatttcaaa gagtcgaata atataaaaaa aggagactgg ataattggat tttcatatga
    18541 taataatttt ttagaagaaa ataagcatcc agataagagt gtactcgata gtgcatcttc
    18601 agaaaatcca atactaattt cacatgcttc tggtcatatg ggagctgcaa atacattggg
    18661 gttaaaacag cttggtgtta ccaatgaaac acgtgaccca gaaggtggac atataggtag
    18721 agtagaaggc agtgaagaac caaatggata tttagaagaa aatgcatttt ttaatgtagc
    18781 atctaaaata aaacaaccat catcaaatga gatttttaat tcaattgaaa aagcacagaa
    18841 catatatcta agctatggta ttacaacagc tcaagaaggt ttaatggaag aaaatcaatt
    18901 taacatttta aaagcaatgg caaatcaaaa taaattaaaa atggatgttg taggatatgt
    18961 aaatttgaaa aaaagtaagt ctgtattaga taataatagg gagtttataa aaaaatatat
    19021 aaatagattt aaagtaggag gttataagat tttcttagat ggttctccac aaggtaagac
    19081 agcatggttg agtagaccat atgaaaattc agatgatggt tattgtggat atcctatata
    19141 caaagatgaa gaagtagaaa agtttataga tatttcacta aaagaaaaga tgcaactctt
    19201 aactcattgt aatggagatg cagcagcaga ccagttgata gatgcgtttg agaaagtttt
    19261 aaacttaaaa gagcaaagta gtgaaaataa tataagacca gttatgatac atgctcaaac
    19321 agtaagagca gaccagattg atgatatgaa agtaataaat atgatacctt catactttgt
    19381 agctcacaca tattattggg gtgatattca tatcaaaaac cttggagaag atagagcgtt
    19441 taagattagc ccacttaaaa caactataga aaagggatta atttacactc ttcatcagga
    19501 tacaccagta atagcaccta atatgctgga aacagtatgg tgtgctgtaa atagaattac
    19561 aaaaaaaggt atacaaatag gagagaatga aaagataagc ccattagatg ctttaaaggg
    19621 tgttactata aatgcagcat atcaatattt tgaagaagat aaaaaaggtt caattaaaga
    19681 aggtaaatta gctaatttga taatattaga tgaaaaccca cttacaatcg accctatgaa
    19741 aataaaagat attaaagtat tgcagactat aagagaagga gaagtattgt attctttgaa
    19801 gtagatgaaa gttagatatt ttataatcta taaaaaatag ttttatataa taagttaggt
    19861 agaattaaat aagattacag ttaaatcaac aattatattt tttattaaat tttaattatt
    19921 gtattgaaga tttataagta taattttatt gattctacct ttttaaataa ctgtcgattt
    19981 attaaagtta tctatgtact atattaaaca attaagtagt tattaattgc acttattagt
    20041 ttattaaaaa actatgtata ttactttgca gtaagacttt ggaactaaat ctataatagc
    20101 aaatttaaat ttattaaata gattacctta taacatttca tataaaatat attgtgaatc
    20161 tgagaaaatt actatttttc tttgagtatt ttttataagc agttctaaaa gattcaattt
    20221 catacctatt acttgaagca ttcattaaaa taattctaat ttaaaaaata attctatcca
    20281 aataatagat atataggact atgttataat ataaaaaaat ttatataaaa gttaataact
    20341 atacaagatt gataaagaaa aagtcaaaat agataattga ttagcaaaat agatataatt
    20401 ataatgaagt taaatctagc aatattctcc taaaattaaa tttcatttat ttaattaaat
    20461 ataatttgac aatggacaaa aaagtgagta aaatataaat aaaataaaaa taacaggttc
    20521 ggataaagaa aaaggtttct taacctcaag cataaagtat attatctaag ttatttgaga
    20581 ttaagagata aatccaatct taggtactga ggaggaaaaa atgcttgata taaaaagaat
    20641 aagagaaaat ttagattgta taaaaaaagc aatggaaaga aggggcgaaa aagactttaa
    20701 ccttgatgaa gtagttaagt tagatgatga aagaagaaag attcttcaag aagttgaagt
    20761 tatgaaacat aaattaaata cagcatctaa aaatatacca aatcttataa aagaaggtaa
    20821 agatgtagaa aatgaaaaga ttaaactaaa agagttatct gataaaatta aggtaataga
    20881 ccaaaatctt aaagaagtag aagataagat ggaataccta ttaatgagaa taccaaatgt
    20941 accacatcca gaagtaccac aaggtgaaac tgatgaagat aatgttgagg taagaacttg
    21001 gggaaagact actacctttg attttgaatc taaggctcat tgggaaattg gaacagaatt
    21061 aggtatactt gattttgaaa cagcgagtaa aataactggt tcaagattca ctctttacaa
    21121 aggattgggt gctagattag agagagcatt attaaatttt tacttagaca cgaatacaaa
    21181 agtaaatgga tatacagaag tcattccacc atttatggca aatagaaata gttttttagg
    21241 tacaggacag ttacctaagt ttgaagaaga tatgtttaaa atagaaggtc tggactattt
    21301 tatgattcca acatcagaag ttcctttaac taatatacat gctaatgaaa tacttaaatt
    21361 tgaacaatta ccaataaatt atacagctta tactccatgt tttaggtcag aagctggttc
    21421 tgctggaaga gatacaagag gtttagtaag acagcatcag tttaacaaag tagaaatggt
    21481 taaaatagtt gcaccagaag aatcttacaa tgagttagaa aagcttacta acaatgcgga
    21541 aactatgcta caattattga atctgcctta tagagtagta aagatatgta caggtgattt
    21601 aggatttacg gcttctttta aatatgatgt agaagtttgg atgccaagtt acaataggta
    21661 tgttgagatt tcatcttgtt caaactgcga agatttccaa gctagaagag caggaataag
    21721 atttaaaaga gataaagatt ctaaagctga atatgtacac acattaaatg gctctgggtt
    21781 agctattgga agaagtgttg cagctatatt agaaaattat caacaagaag atggttctgt
    21841 ggttgttcct gaagttttaa gaccatatat gggagtttct gttattaaat aagagttaaa
    21901 ttatgtattt ttaagcaata caataatata gaagtaataa aaaataatta atataaaagt
    21961 gatacaataa tatagaagta ataaaaaaat agttaatata aaagtgatac aataataata
    22021 gaagtaataa aaaaaaataa ttaatataaa aatgtgtaca aactaatgaa tattgatata
    22081 gtaagctatc atatgaaaga gtatgtacac atttttttta ctaatttttc acaatatgaa
    22141 cataaataat ttacaggaaa ggaatctttt atgaaaattc aaaatactga gtggggatat
    22201 attgaatgga aacatactta tgatgaaaat aatccaaaac aagctatgaa tatatacatt
    22261 gcagtaacta tgcctggtaa gaaacatttt aatcatgttc attatggtca agagcagatg
    22321 atatatattt tagagggaga gggtttgtat attataaatg gagtttggaa gccattttat
    22381 caaggtatga ttttttatat agaatctggt agcacacatg aaactataaa tacaggcgat
    22441 agagaaataa aagaacttat tgtttcaaat aatgtagatg atgtaggaga gagtgaagtt
    22501 atagatatta atcctaataa ttatttaaag aagaccttga taaattatag tgaaagtaca
    22561 ttaaatttgt atgcagcagt agaatcaatt cgtggtcaat ttatagaccc gtttaaaatt
    22621 ccattaatta tatatgatga ttcatggaat atagttttaa aaaaccctta ttttccactt
    22681 ttttgttttg aaaaatgtaa tcctatgaaa tttcctcaaa attgtgattg tatgaatcaa
    22741 aaaagtagca atcaatttgt atgtgaatat gggataacta tatataatat accaatactg
    22801 tacaaaagca atagcatagg tgttataaga ggagggtatg tactattatc tgatttaaat
    22861 ttagatacag agcataataa tttatatgat attccagagg gagctgctag aagtataaaa
    22921 cgcctcttga aacaaatatc taaaaatata ataaattttt gctcttttaa tgatataaga
    22981 aaggatttac aagaaaaaga gaagactata gcaagaacat atcattatgg agagcaactt
    23041 gaaatgaatt taaaagtagc tcaagatatg gttactaatt taagaataaa tcatcacttt
    23101 ttatttaata cattaaattc aatggcaagc atagcactag atgatggtag ttatgatttg
    23161 tatagtgcaa taatagattt atcaagaatg tttagatata caatgaggtc tgatttaaga
    23221 tttgtagaat tagaatctga aatattatac attaaaaatt atttgaattt acagaaatta
    23281 cgttatggag atgcacttaa agtaaaatat cttattccag agaagttata taacctttct
    23341 gtgcctttta actttattca acctatcgta gagaatgcat ttacacatgg atttagagat
    23401 attgacacag aaaagcgaat tgaaataatt gcaagattag attctcagta tgctattata
    23461 gagattcata ataatggaac tatcttagat ggaaataata tagacaaaat aaaggcaggt
    23521 attcgtagta ataatggtca tggtttgtct ttaatatata caaaattcac atctgcttat
    23581 ggaaataatt ttgatatgga tataaagtcg agtgataatg aaggaactta cataatgatt
    23641 aaaattccta ttgaaaatta taaggagtat gtatagaact tgtgaaaaat taataagttt
    23701 tataaatgtt aagaaatata ttagatgttt ttatgttgtt ttatatatct tactttttta
    23761 tattattaag ctaaaaggga ggtattctca tgagaagagc actaataata gatgatgaag
    23821 aagctgttct aaaaataata acacatttta tagaaatgaa agatatgcca ataaaaattg
    23881 ttggtaaagc aacatctggt gatgaagcag tagataaaat cattggttta gagccagaca
    23941 tagtttttat agatattcaa atgccaatat acaatgggtt agaagtaata gaaaaaacat
    24001 ctcatttatc taaaaaaata aactttgtag taataactgc atttaactat tttgaatatg
    24061 ctcaaaaagc tttgagatta aatgtaaaag atatactcct taaaccattg gatatgaaag
    24121 aatttactaa gtctgtagaa aaaattattg gatatcaata taccaataat gatttattaa
    24181 atgagatact ggaatatata aatctaaact atagcaatga cttaaagtta aatgattgtg
    24241 ctagattatt tttaaccaat ccatctaata tatctaggat ttttaaaagt aatttaaata
    24301 caacttttat atcatatcta aatcatataa gaatagaaaa atctattgaa ttacttgaaa
    24361 atactacaaa aagtataaat gagattgcag aaatagttgg atataatagc ctaaataact
    24421 tttataaaaa ctttaagata gaaaaaggaa tgactccaaa agtttataaa ctgaacacta
    24481 aaaattgaaa ttgataaata aaaagtcaat atagataatt gtttgagtgt gtctgaataa
    24541 gtatacttta attatgataa aaattaaagc gctttaaaca tatttaataa tattaaacct
    24601 tataaaagct gtacctattt atataaaaaa atatatataa ataaaaagaa aaagatatac
    24661 aaaataaaaa aagtgaatta aatactgttt caaaaagaca gaattttcat ttaattcact
    24721 gagagtttat atttcttaaa ggaaggtaac tttataatgg aggtaattta atatgtcaga
    24781 caaagtgaat atgaaaaata ttatctgtat tgcaggcgct tatctagcaa cagcaattgg
    24841 ttctgggttt gctactggtc aagaaattct acaatttttt gcctcacaag ggtatatggg
    24901 tttaattgga gcattaatat caatggtatt gttttcattt cttggtgctg aagttataac
    24961 tagaggtaga gaattaaaac ttaaagaacc aacaagaatt tacacttttt attgtgggaa
    25021 gattttagga aaattttacg aatggtttag tccaatattt ttatttggga ttcttatagt
    25081 aatgatttca ggtgcaggct caactttaac tgaatactat ggtataaatc cttacttagg
    25141 aagagtattg atggctgttg ctactttaat tacagtgtct atgggtttag aaaaattagt
    25201 aagcatactt ggacgtattg gaccagtgat agcagtattt acaattgctg ttggattaat
    25261 aagcttgttt aagcattttg atggtttatc tatggttgga gaagctatga aaaatattga
    25321 agttacaaaa gcatcagaaa gtccaatcgt ttctggtgta atatataata cattaaatat
    25381 tattgtaatg attgtttttt taacaggaat gggagcttct attgaaagta aaaaggatgc
    25441 tttttgggga ggtttattag gtggaatagt gtttatgact gctggtatag ttatgtattt
    25501 ggctatgatt tcagatatag gaaatttgta tatgaaagaa ataccatcac tttatttagc
    25561 agataatata tctcctattg taggtgtatg tttttcagtt gcattaatat taggtatcta
    25621 tacaacagct gttccacttt tatggtctgt aaccaataga attgttgaag atgaacatcc
    25681 taaatttaaa ttggtaacaa cagtaatagc tattttggct tgtataggtg gttttttacc
    25741 gtttggtaaa ttagtaaaca ttttatatcc atatacaggt tatatggggc ttttaatttt
    25801 agtctgtatg gtgtataaag caattacatg tagaaaaaaa tcaacacaaa gtcaggaata
    25861 gagtcaccta ttaatagttt ttatttaaag aaatttttta tataatccga atttaaaaag
    25921 tcaaaatagt taaataaatt gcaaaacatg ataatatatt taattaaaat aatatagtaa
    25981 aatataaata taaactaaaa ttaaatttat aaaaaatatc tttataaaga ttattaactt
    26041 atataatttg tagttaaatt ataaaaaata aaaaaataaa attttggaga ggtgttagta
    26101 tgcatgaact tattttaatc tcagaaaagt ataaagaaga tattttagat ttttttacag
    26161 atattcatat gcaccccgaa ttaagtttta aagaatttag gactacaaaa gctataaaag
    26221 atttattagt aagtttagac atagaaatat tagatttagg aatggaaaca ggagttgttg
    26281 gattattaaa agggaagtat gatggtccca cagtagcact gagaggagat attgatgcat
    26341 tgccaatata tgaagaggtt gatattgagt ataaatccag atatgatggt ataatgcatg
    26401 catgtgggca tgatatacac acatcttgcc ttgtaggatg tgcatatgta ttgtctcata
    26461 ttagagatag tcttcatgga aatgtaaagt ttatatttca accagccgaa gaagtcaata
    26521 aaggtgcgaa gatgctagtg gaacgaggag taatggaaaa tccaaaagtt gatgctatat
    26581 ttggacttca taatcatcca gatatacctt gtggaaaaat aggtgttaag ttaggtgggt
    26641 taatggcagc agtagacact attaagatag aagtaaatgg atttggaggt cacggaggta
    26701 taccaaacag aacaatagac cctatagtag catcaagtgc aattataatg ggtattcaaa
    26761 ccatagtaag cagaaacata agtccattag aatcagctgt tatatcaata ggtactataa
    26821 atggagggac tgcaaataat gtaatttcag aaaaggtaga tatgacaggt acatgtagaa
    26881 gctttagtaa tgaagtacga aagaaaatat cagaaaattt agaaaatata gtttgtgaga
    26941 tagctcgtgg atatcaagca actgcaaagc tagattattt atttgattta ccagctgtta
    27001 taaatagtaa agagatgtac acaatagctt gtaagtctgt gtgtgatttg tattcagaag
    27061 atgctatagt tgatccaata ccttctacag gaggagaaga tttttctata tttatggaaa
    27121 aggccccagg atttttttac tggttagggg taggcaataa agaacaagat tgtatatatc
    27181 agtggcataa tcctaaattt aaagctgata aaaattctat attggtaggt acaaatgtac
    27241 tatgtcagtc tgttataaat tatatggata aattaaaaaa taaaatttaa gatagagcat
    27301 tctggagata aagtttatga gggggtatta gtttgaggaa aattaattca caggaaaaaa
    27361 acaaagatag tggattattg atgagggcac taaatgttgt agagagagca ggaaataaac
    27421 ttccagaccc agtaaccata tttttattac tatgtataat tgttgtaata ttgtcagcag
    27481 ttatatctaa tttaggagta gaagaaatac atccttctac aaaagaagtt gtaaaggtag
    27541 taaatctact agagaaagag cagattcaat catatttagg tagcatagtt acaaacttcc
    27601 agtcatttgc tcctttagga ttagtactgg ttacaatgct tggagcaggt gttgctgaga
    27661 aatctggatt tatggaagtg ttaatgaaaa agggtataag taaagttcca caaaaacttg
    27721 taactgtagc aatcgtattt gcaggtatgt tatcacatac agcagcagat gtaggattta
    27781 taatattacc accacttgca gcacttgtgt ttttaggaat tggaagacat cctcttgtag
    27841 gtatgtttgc agcttttgca ggtgttgcag ggggatttgc agcaaatgtt atgcttagta
    27901 ctacagatgt attgttagct ggatttacaa taccagcagc tcaaatgatg gacccatctt
    27961 accaaggcaa tccagcaatg aatctttatt ttgcttttat atcagcgata gttttaactt
    28021 ttgcaggagc atttgtaact gaaaaattta tagctcctcg ttttacaaaa tataatgatt
    28081 caacaaatga taaggatata caggaattga gtgaacttga aaataagggt ataaaatacg
    28141 ctttattatc attgttagtt gtagtagtag tgatagttgc cttatgtata ggtgacaatg
    28201 catttatgaa agatccagag actggttcta tactatctag taatgcacct ttaatgaaag
    28261 gtatagttcc tataatcact attatatttt taactccagg attagtgtat ggaaaagtaa
    28321 gtaagaagat aaaaagtgac aaagatttag tatctatgat gggtagtagt atgagtgata
    28381 tgggtggata tatagtccta gcatttatag catcccagtt tattaattta tttaatctta
    28441 gtaacttagg aacaatttta tcaataacag gagcaaaatt actagcagag tcggggatac
    28501 ctagctatgg attgataata ggatttatat tgctatctgg atttatcaat ttatttgtag
    28561 gaagtgcttc tgcaaaatgg gcgattttag cacctatatt tgttcccatg tttatgctac
    28621 tagactttaa tccagcatta actcaaatag cttatcgtat tggagatgct tcaacaaatc
    28681 caataagtcc actttttccg tattttccag ttatattggc ctttgccaga agatatgata
    28741 aagatatagg tataggtact gtcatatcga atatgattcc atactcagtg gtatttacat
    28801 taatagaaat aataatattg ttactattca tgggtattgg cataccatta ggacctggtg
    28861 gaggaatatc ttacgtttta tagaccatta taataaattt atcaatgaag attaaactaa
    28921 taaaatatat tctttaatta agaggaggat tattatgtta aaaacaacaa aaatttcaga
    28981 cccagagtta tacaagattg tagctgatga gttggttaga caagaacaca atattgagat
    29041 gatagcttct gaaagtacag caccaacaga agtacttgaa ttaagtggat gtgtatttac
    29101 aaataaaaca gaagaaggct atccaggggc tcgttttcaa gcaggttctg aagaagcaga
    29161 taaacttgaa accctagcaa taaaacgtgc aaaagaagta tttggagcag aacatgtaaa
    29221 cgtacaaccg tattcaggtt ctacagctaa ctattgtgta tattcatcaa tattaaaacc
    29281 aaatgacact gttttaagta tgcgtcttga ccaaggtgga cacttgacac atggtagcgc
    29341 agttaatttt ttacatgaca tttataaata tgaattttat ggggtagacc caaatactgg
    29401 acgtatagat tatgatgctc ttgaagcaaa ggcaaaagaa tgtagaccaa aacttataat
    29461 tgcaggggca agttcatatc caagattaat agattatgaa agaatatcaa aggttgcaaa
    29521 agaagtagga gcttacttta tggtagatat ggcacatgtt gcaggattag tcgcagcgaa
    29581 agtaatacct agtcctgtac cttatgcaga ttttgtttct tcatctacga caaagacttt
    29641 ctgtggacca agaagtggta ttgtactttg taaagcagaa catgcaaaga aactcgataa
    29701 aggtgttttt ccaggaacat tagggtctat acatcttaat acagttgcag caaaagcctt
    29761 ttcactatta tatttaagta cagataaatt taaaaagata atggagcaag ttgtagtaaa
    29821 tgctcagact ctagcttctg aactgatttc acatggtttt agtattgtaa gtggaggtac
    29881 tgataatcat atagtaatgg ttgacttaag aagtaagaat cttacaggaa aacaatttga
    29941 aaaagctctt gaatatgtag gaataacagt taataaaaat gttatacctg acgacccaca
    30001 atcaccattt gtaactagtg gtgttcgtat aggtcttaca tcaatatctc aaagaggtct
    30061 gaaagaaaaa gaagttatac agatagcagg aataatgaat aaggtagcag aaaatattga
    30121 taataaagaa gtattagatg aatgtaaagc agaggcacaa gaacttatat ctaagttccc
    30181 attatatcca gaagggtatt ttgaagatta aatattttga tttgtatagc tcacaattta
    30241 taaagcctgt aacataaaat ttaataatat ataaccacta taaggtgttg attaatcaac
    30301 accttatttt ttttgaaaag taatatacaa gctatcataa gcatataatt ccttatagat
    30361 aattaacaag ggggataaag ttatgaggta ttataataaa cctaccaaag aagtattaaa
    30421 atacttaaaa acaaatccag aaattggact tgatgataat gaagtagaag aaaggaagct
    30481 tagatatgga ttaaatgaat ttactataaa agaaggtaga acattttggg acgagttggg
    30541 agaaagtttg acagaaccta tgatattaat tctcatagga gcagcagtaa taagttcttt
    30601 tgtgggagaa ttacatgatg cattaggtat tttaggggct atttttattg gaatttctat
    30661 aggcataata actgaaggaa aatctaaaaa agcagctcag gccctgtcaa aattaacaga
    30721 aaatatagaa gtaaaagtac ttagaaatgg aaagataatt aaaatatcaa aaaatgattt
    30781 agtaccagga gatattgtat atatagaaac tggagatatg ataccagcag atggaagact
    30841 tatacagtct ataaatttga aacttagaga agatatgcta acaggagaat ctgatgatgt
    30901 agctaagaat gctgatgctg tattagatat ggaagtagtt tattctaaaa cagaaataat
    30961 cgaacaggat gcaatacctg caaagcaagt caatatggta tttggaggga ctcttgtagc
    31021 atatggtagg ggcataatgg ttgtcactca tactggtgat aagacagaga tgggtaagat
    31081 agcacagaat ttatcaaatg aagaccagca aactccactt caaattaaat tagggaagtt
    31141 gggtgctaaa atagcaggaa tatcaggcgt aatagctact ttattgtgta tgtttatgat
    31201 tatacagatg cagagaaaag gtatgttaat tttagataca agcagtatat tatctttctt
    31261 acaatcatta gaacctgcta aaaatgcata tatggtttgt attgcattaa tagttgcaac
    31321 tgttccagaa ggtttgccaa ctatgataaa tattacctta gctataacaa tgcaaaagat
    31381 ggcaaagata aatgcattag taacaaagaa agaagcctgt gaaactatag gttctgtttc
    31441 tgtaatatgt tccgacaaaa cagggacttt aacacaaaac aaaatgatgg tagaggtagc
    31501 atatgttgat ggtaaatata taagtggagg agagtatcaa agtaacagct attttgaaca
    31561 aaactgtata gtaaattcaa ctgcagatat agaaaaagaa gataattcat ttaaatatat
    31621 aggaagtgca acagagtgtg cattactttt atatcataat gataagaact ataatgaaat
    31681 gagaaaacaa acgtatttga tatcacaaat accatttagt tcagaagaaa agaagatgtc
    31741 aacattaatt cgtcaagagg attcagatat attactttca aaaggtgctc cagaagtatt
    31801 attaaaaaaa tgttcttatg tacaacaagg aaaaaatatt gttccaataa ctccaaaagt
    31861 agaaaaaagt attttagatg agattaagaa gttacaaatt aaatctatga gaacattagg
    31921 atttgcttat aaaaaaatga gtaattctaa aacagaagtt gcaatgactt cagaaggtga
    31981 attgaattta ataggaaatt caagaagtta tatgaaggaa gataatttag tttttagtgg
    32041 atttgtagga atagtggacc cattgagaga aggggtcaaa gattccattg ataaagcatt
    32101 taatgcagga gtagatgtaa aaatgcttac aggagataat ataaatacag caacggctat
    32161 tggaaatgaa ttaggattat taaatgatgg gaaaaaggca gttgaagcaa catatataga
    32221 tgtattgaca gataaagaac tgagagaaga aattaaagga atatctattg ttgcaagaag
    32281 taaaccagat acaaaaatga gaatagtttc agcgcttcaa aaaagtggcg aagttgtagc
    32341 tgtaacaggt gatggtataa atgatgcccc agctcttagt caagcagatg ttggaattgc
    32401 aatgggtatt tcaggaacag aagtatctaa aaatgcagca gatataatat tgactgatga
    32461 tagctttagt actatagtag agggaataaa atggggaaga ggtatatatg agaactttca
    32521 aagatttata cagtttcagc ttactgtaaa tatagtagca tttataattg ctataatatc
    32581 tcaacttact ggtaaggata tgccatttac tacaatacaa ttattatggg taaatataat
    32641 aatggatggt cctccagccc tagcattagg attagaacct gttagagatt atgtattgaa
    32701 aagaaaacca ataaatagac attctggaat aatagctagg tctatgtttg taaatattat
    32761 tataaatgct attcttataa ttacaattgt atttactcaa tcagctttta atatattggg
    32821 agctacatca gaagaacaag gtactgttat attttcttta tttgcgttca gtgccctttt
    32881 taatgcatta aattgtagag aatttggttt aaatagtaca ataccaaatt tctttaaaaa
    32941 taaactggca ttgcaaataa tagtagttac agggataatt caaataatat ttacacaagt
    33001 gttccagagt ttctttaatt ctgtttcttt ggactttgat atgtggataa aaataatact
    33061 atttgcatcc actatattat tgtcaaatga atttgtaaag ctaatactta gaacaatgaa
    33121 aaatagtaga agtatgaact ctaatagtaa aaattaattc ttatgaaacc gcaaagtact
    33181 atatattgta actttgcggt ttttgtttgt ttaatgttgt tttatattac cattttcata
    33241 tttaattttt tattaatctg aacacaatct tccattgtaa ttgcttcatc tgtgtcaaca
    33301 cgttcaaagt caatatctaa cttttgtaat attttgtata cctctttttg caatggagta
    33361 tcaaatttaa taggtgattt tgtgtaaata tcactgataa aaaacatgat ttatttcatt
    33421 cctttccgtt taaaatctta tagttatagt gtatcataag gttataaaaa cataaatata
    33481 gtataaattt aaaatatgta aagacaaaac aaaaaaatca tattctaagt aatacttggg
    33541 aaaaatgata ttatcataat aaataatctt tgtaaaaact tatatagaat ctattaaaca
    33601 gacactaagc cataaaaact ttacgaaata taaaatttgt atctaaatag atatatagaa
    33661 taatatttta ctgaagtaga gtgattttta agaattttat atataaatta tgttatcata
    33721 aataaagata tagattataa aatttgttaa taaaataaag ggcagggagg taagtttcat
    33781 gttttccaaa atcctagtca aaacatttat cagagatagc gaaaacgttc aaaatacaga
    33841 tgttagaaat aagtatggtt atgtagctgg tgtagtaggt atattgtcca atttactttt
    33901 atttgtgata aaggtattca taggaatgtt cacatctagt atagctataa tggctgatgc
    33961 atttaataat ctttctgata tggcatcttc agcaataact atgataggtt ttaaattagc
    34021 aagtaagcca gctgacaaag aacatccttt tggtcatgga agaatagagt atttatcagc
    34081 attaatagta gcatttatgg tgatgttggt tggacttcaa tttgtaaagt catctataga
    34141 aaggatagta aatccaattc ctgtaaaatt tgaagtaata ccacttatac ttttaattgt
    34201 atctataatg attaaaatct ggttgagtcg ttttaataaa tttgtgggaa ataaaattga
    34261 ttcttcagcc ttaaaagcag tttcacttga tgctttagga gatgtattta cttcaagttg
    34321 tgtagttata tcatttattg tagctagatt tactaatttt cctatagatg gatatgttgg
    34381 tatcgtagta tcattagtga tactttatgc tggtttctct cttgtaaaag atactataaa
    34441 tcctctttta ggagaagcac cggatgaaga aatggtaaat tctattatag agctattgtt
    34501 atcttataaa tatataatag gtacacatga tttaattatt cataactatg gagttggtag
    34561 atgtattgca tctatacatg cagaaattcc atccaacata gatataatgg aaatacatga
    34621 aattatagat actgcagaga gagaaatatc tgaaaaatta gatatatatc tagtaattca
    34681 catggaccca atatgtcttg aagataaaga agttatgtca gccaaaaaag aacttgaaga
    34741 aatacttaag aaaaatagtc ttgtaaaatc tatgcatgat tttagaatag ttggaaaagg
    34801 aagcaagaag aatttaatat ttgatatagt agttaatcct tccgaatttt ccaaagacat
    34861 gtcagaggat gacttaaaag aagatataac aaaattagtt aaggagataa atcctgaata
    34921 taattgtgta attgttgtag ataaggattt tatttaatta ttaattaatc tcataaaagg
    34981 taaaaaatgt aaaaaagata gacaatagta tagaggcata atataataga agtatataat
    35041 tgtattttta atataaataa agcaatttta attgttttta tgaaatatta tagagatgtt
    35101 gaagtatatt ctattattgg gcaccttatg gatatactga gtcagtggtg caaccggcta
    35161 tgaatataaa tttatttatt ttcatagctt tttttatata attttttagt aaaaattaat
    35221 ttatatacga tattaatgga agattataaa ctatagataa cctagagggg gaaaatttat
    35281 atgaagaaag gaaataaaaa ggcattatta attagtttaa ttatgatttt aagtatggtg
    35341 gtgtctacaa tatatccaac tgtatcttat gcttcagaat taggagagaa tagtcagatt
    35401 caaagtggtt caactaattc atcaactgga gaggagaagg aaagcgacaa taaaaaacca
    35461 gaacagactc cagagaaaga taaggcaaca gataataaaa aaccagaaca gaccccagag
    35521 gaagataatt caacagataa taaaaaacca gaacagactt cagaagaaga taagtcaaca
    35581 gataataaaa agccagagca aactccagaa ggagaaaagc caatagataa taaaaagcca
    35641 gagcaaactc cagaaggaga aaagtcaata gataataaaa agccagagca aataccagaa
    35701 gaagataagt caacagataa taaaaagtca gaacaagctt tagaagatga aaaaccacta
    35761 gacaataaaa atacagaaaa aactccagag gaagataatc tattagaaga tgaaaattta
    35821 ttgaaagttt tagaagaaga acttaatgaa gactatggat ttgttgtaaa aattaataac
    35881 aatacaatag aaacggaatc aatgaaaaaa atatcattta atttaactta tactccaaca
    35941 tcaaaaggaa tacaagcagg agattcaata acttttaagg tgccagatgt attcaataaa
    36001 gttaatttag attatacaag tgaatgcttt gataaaacag aaagtaatgg agagtataca
    36061 cttacattta gagaattacc taatggccaa agtgtaatgc aaggtaaaat aggtttggaa
    36121 gcatatgtta aaaaggttga tgaagatact aatgcaaaaa tacatattga aaccactgga
    36181 aaaatagaaa gtggaagtgg agatatagat gtagaaataa aacctggaga taaaacggat
    36241 gttccagatg ctaaaggaac acttaaaaag cttgttgaag gaagaaaatc aactactgta
    36301 tttatgccag ttaaaaataa agatataaat tacagtatac aagtaaatga aaagcaggaa
    36361 gagttaaaag atattatttt gtatgatgag cttcctgaag gattgacatt gataaatggt
    36421 tctgtaagtg tagtaacaag tgatggaaaa gaagttagtg attttaatat tgaacagagt
    36481 aaaaattcta tttcagttaa ttttggaaat atagataaat cgtatactgt taagtataag
    36541 gctagaatca gtgacaaaaa tgcaaaacat ggtaataaat ataagaatgt agctaggatt
    36601 gaatctgatg gtaagaagat acaagaagat gatgctactg taagtatatt tgatagagga
    36661 gataattatc ttcttactaa aggacattca ggagcaacaa atattactca agttggtcaa
    36721 gtaataaact atcagatttc aataaatgat gataaatcac caataagtaa tgttgttata
    36781 acagataata taccagaagg tatgagattg actacttcag gagaggatgg gcatgatttt
    36841 agagttgtag aagttccaat gaatgggagc tggactcctt ggagtaaaga aaaaattgcc
    36901 aataatattt catataaagt agaagaaaaa agaaatgaaa gtgggcaagt agataaagtt
    36961 ataactggat ttacaattaa tctcagtaaa gaagaagtag aatcaaagtt ttttatagct
    37021 tatacattaa aggtaattag tattgaagat agttatataa atagagctgt ccttgatgca
    37081 aataatagtg aaattgataa aaatgatgag ataaacttta agaaaaattc tggattaata
    37141 agcgcaaaaa aagaagttga taaaaaggtt ttaaatagta gtgataacca gattgttaaa
    37201 tacaaaatca atatgtcaac ttatggggtt tatgatgcag gacaagtaaa tcttttggat
    37261 gaagtaaacc catctctaaa aatatctaat ataaaatatt ctgataatct tgaacttaaa
    37321 aaagaagctg gagatggaaa aaatacaata agattagtaa ataaatacga atttaaacag
    37381 ataaaagaag gggaacctgt gcaaagctgg gttacatttg atgcagactt cacaaatgta
    37441 aaagttgggg agactataca aaatgtggct cagattaatg gttcaagtcc tccgggagta
    37501 gagactacta agcaaggtta tgcttttgaa gctaaaaaag tggatgcttt agataaaaat
    37561 gtactttcag gtgctaagtt caatttagaa gatgcatttg gaaatatagt agttaaggat
    37621 ttagttagtg atgaagatgg tgtaattcaa tctagtgtaa aaaaaccagg aatatattat
    37681 ttagtagaag tgatggctcc aagtggatat gaaaaactga aggataaaat taaggttgaa
    37741 attggtaata aagatattgg tagaatagta gatatcggaa atatagaaaa cataagacaa
    37801 gaaaatccac cagtaaatcc acctgtaccg ccaaatacag atgaaccaat agtaaatcca
    37861 ccagtgccac caagcacaga taaaccaagg aaaccatcaa atccatctga tacagaggat
    37921 actatagtta taaatccacc agtaccaccg tcagaagata taataaatcc tccaatacca
    37981 gagatattga atccaccagt accaccatca gaagaggtga tagaaactcc tgttaaacag
    38041 attgttccaa taccagaagt ggtaaagcca tcagtgtcag aagaaaaaaa taataaagct
    38101 aaagatgata ctttggtaaa tccaccagta ccaccaaaaa caggggatag tactacaatt
    38161 attggagaaa tacttttagt tataggagct attgtaggac ttgtcgtatt aagaagaaat
    38221 aaaaatacaa attagaccct aacattataa aaaatataag ttatattaaa aaatatcttc
    38281 taaaacaata tttaataatg aaaatattgt tagaagatat ttttttttga agatttatgt
    38341 aaaaaaataa taacttttta gaaaaaagtt ccaaagggat atagacaatt aaaaagatat
    38401 aagctataat atagatataa aattaaatga ggcaaaacta gggaaaccta gtcacgcaaa
    38461 gctatagggg ctaaagttta gtaaaccatg ccagccagtt gccgaaaaga gtaaaaattt
    38521 ctttttgtat atacaaagat actcttgggt atctttttta ttttgaaatt tattactccc
    38581 ggcctaactc aaaggaggga ataatatgag accaagtaaa aaattattaa tagctataat
    38641 atcaatattc ttaataagtt cagttccagt aagtgcacat gcatatagta ctactataca
    38701 acaaaataaa gacacactta gtcaaatagt agtttttcca actggaaatt acaataaaaa
    38761 cgaagctaat gctatggtaa atagattagc taatatagat ggaaagtatt taaatgtatt
    38821 aaagcaagat aacttaaaaa taaaattatt aagtggaaag ttaacagatg aaaaagaata
    38881 tgcttattta aaaggtgtag ttcctaaggg atgggaaggt actggaaaaa cttgggatga
    38941 tgttccaggc ttaggtggaa gtacagtagc tcttagaata ggatttagta acaaaggtaa
    39001 agggcatgat gcaataaatt tagaattaca tgaaacagca catgcaatag accatatagt
    39061 attaaatgat atatctaaat cagcacaatt caaacaaata tttgctaaag aaggtcgttc
    39121 tttaggtaat gtaaactact taggtgtata tccagaagaa ttttttgcag aagcatttgc
    39181 atattactat ttaaatcaag atacaaatag taagttaaaa tcagcttgtc cacaaactta
    39241 tagctttttg caaaacctag ctaaatagag ctttaataaa tttaaaataa atataaaaga
    39301 gatgctatta taatagcatc tcttttatat tgcgtttaaa tctaataaat tttgtcttat
    39361 gtataacttg atagattatc aattactact ccttatacaa ggcttcaacg tgtttattat
    39421 gcatttgagt aattatcgta ggtataatag aaattattga accaattact atcaataaaa
    39481 ttcctataac catgtttata gggataattt ctttaagtat taataatgct agtattggag
    39541 atagtactgg tttaaagaag aatactaaag atgtaagact agtagatgta gcttccattg
    39601 ccataaagta aagtgcataa ccaacacctg taacaaatac gaatacataa atcataatgg
    39661 gcatattgtg taaggtatat ccactaaaaa tagggatatt tgcaaatata tgaagtttat
    39721 ttttatttaa tatatctgcg ataaaattaa ttttagtgag taaaaccaat atcaacattt
    39781 ccaaactacc aaatataaag ctaaagcaag ttacaactat tccaccaaat tttaaggttt
    39841 ttcttttacc aaatacagta tacattgaaa aaataatagc agaagataat gttaagaata
    39901 ttccactaag agttagtttt gtatgcaatg gatttattat aactataatt ccaagaactt
    39961 ctaatataag tgaaattaca ttgtgcctat atattttttc cttcaaaatt aagtaagcta
    40021 aaagcattac aaagactgga ttacaactga acaaaacagc aactacagat gcctttgtgt
    40081 ttagaacagc cagttgatac aatgacatac ttactactac acacataaaa cctaaaaatg
    40141 caaagtattt taagtctgat tttgtaatag aaagactaag agctcttaat ctttttacag
    40201 caaaaggtag taagactaaa ccgccaacaa aaaatcttga taaagttatt tgtaagggat
    40261 taaagtcatt agtgacagtt tttagactaa tttccattga actaaaaaat aaggtagtca
    40321 gtattatata aacataacct tttttcaagt caaacacctc cttgtaattt atattagtac
    40381 tatagataag aatattcaag catattggaa taatatggta tgtataaaat atagtacata
    40441 aaattataaa ctaccttaat atagaatgta agtattctat actaaggtag ttaattattt
    40501 gaattacttt gatttagtta ttttaaatta tataatttgg ctaatttttc aaatgctggt
    40561 aaagaacttt taactttatc ataagataca caatatgata ctctaaaatg acctggacaa
    40621 ccaaaagaag aacctggtac taataataaa ttaaattgtt ttgcatcatt gcagaatttt
    40681 ttatcatctt caattggagc ttttgggaac aaatagaatg taccattagg tttaacacaa
    40741 gaatatccca tatcgattaa actattatat agaaggtcaa aattcttttt ataaatattt
    40801 acatcaactt ctgcatctaa acttcttgca ataacccttt gaaaaagaga aggagcattt
    40861 acaaatccaa gtattctatt tgcaacattt aatgaagaca taacatcatc aaaatcatcc
    40921 atttgcccat tagcaacaat atatcctata cgttcaccag gtagagataa tgatttacta
    40981 taagagtacc ctataaatga atttctatag tattttagta cacaaggaac tttggcacca
    41041 tcataaatta tttctctata tggctcatca gaaattagat atatgcttgt attaaattct
    41101 ttttgttttg aatccaataa ttctccaaga ttttttaata attcttcaga atatatgaca
    41161 ccagtaggat tatttggagt gtttattatt aaagctcttg tttttggagt aatagcattt
    41221 tttagagcat ctaaatctgg ttcaaaagtc tctatatttg taggaacttc tattaatttt
    41281 ccatcatagt tttctgtata atttttatac tcaccaaaat acggtgcaaa agcaataact
    41341 tcatcaccag gatttaaaag agtttttaaa ataatattta gaccaccagc agcaccacaa
    41401 gtcataatta aattttctct tgtaagattt aatccatctt ttttatttat atgttcagca
    41461 atagcatctc ttacatcctc atatcctgag ttgttcatat atccatgaac taaatttgga
    41521 gattcttcat ttaaaatatc atttataact gctttaatag tctctggagg ttcaacactt
    41581 ggatttccta tactaaaatc aaaaacattt tcctcaccat aaatatcaga aagtttcttt
    41641 ccttcttcaa acatagctct tataacagaa ctatttgcaa ctaaagtttg cattttatta
    41701 gatatcatat gtaacactcc tttttataga tttatattgc ttatgtatat attaccatat
    41761 ttttactgaa tttagacaat tttcgaaaaa ttacttgttt gaaaatataa acttttatat
    41821 aaaatatatt tatgtacagt gcatattaaa aattccaatt tctaatttta tcatgattat
    41881 tttatataat agttttttaa agaattaata aaacatagat ttagagaata aaatattctt
    41941 gactatatta attgtttaat ataatatagt tgatatagtc aaacatatta taattataga
    42001 agggaaattt aagatggatt ttaaaaattt acagtatgaa agtttgtcat atattatttg
    42061 taacttgcaa aaaaacttta aactttattg tgaaaaatgt ttaaaaccat ataaacttac
    42121 gaatggtcta tatttctatt taatttatat taataaaaat aggaattgtt ctttgaatga
    42181 tgtttctaca gaatttgaag ttgataaagc tcatacaaca agaactatat ctaggttaga
    42241 acaagatgga tacatagaaa aaatccaaaa ccctaatgat agtagagctt ttcagttgag
    42301 agtaacagat aagggtgagg aagtattagg ggatataaaa aacatatttt caaagtggga
    42361 taaccacata aaaaaagagt tctcagatac agaatataaa gaactggtaa agaatttaca
    42421 tgtggtaaag gatataaaaa cagctgtgga ggaaggatag gatgtattgt aatttattaa
    42481 aaccaattaa aattggaaat ttggaattaa aaaatagagt atcttttgca cctacaagca
    42541 tgggtcttaa attggaagaa aaaattaaaa agttttctga tattgctaag tcaggagtag
    42601 ctctgattac tctaggagat gtatctatta gacctagttt tcataaggta gctataagcc
    42661 tatcggatga agatggagtc attaaataca agaaaattgt agatgaaata cacaattctg
    42721 gtgcaaaggt atcagcacaa ctattttgtt cagattatga tgttaattta attaaagata
    42781 ctatgaagat gggaattact tcacatgatg agataaaaaa aataatgaat gacggagtaa
    42841 aagattacat aacaaatatg cccaaagaag aaattaaaaa tattataaat ttatttaaag
    42901 taacagcatt gaatgcaaaa aaagcaggtt ttgacatgat tcaaattcat ggtgataggc
    42961 ttgtaggaag tttttcatca agtatattta ataatagaaa tgatgaatat ggtggaacgt
    43021 gtgataatag aagtagattt gcaagcgaaa taattagtag tatccgagat gaagttaagg
    43081 acattccaat agactataaa tttgcaataa gacaagaaaa tcctcattat ggaaatgcag
    43141 gagttttact ttcggaagtt gagtattttg ttaaaaaatt tgaatcccta ggtgtaaaca
    43201 gttttcatgt aacacttgca aatcattcaa aattagaaga tactatacca accaataatc
    43261 atccttactt taaagatgaa ggctgttttt tatatttagc tgatgaagta aagaaacaca
    43321 caaatcttcc agtatgtggg gttggaaaat tgtctagccc agattttata gaaagtatta
    43381 tttcaaataa tagagtagat atggtttcta tgtcaagaca attactagca gatagtaatt
    43441 ggttacagaa agtaaaagat ggaagagtag atgagattaa aaagtgctgt tattgtaata
    43501 agaagtgtgc agatgcttta caaacacgct ctcagtttgg atgtatacta gattagaata
    43561 tctttataaa aataaataat ttgttaaggt taatatattt ttggtgattt agataagtat
    43621 ttagataaag aggaggagac atcatgaaaa gtttagtttt atattcaagt ttaactggaa
    43681 atactaaaaa gattgcttat gctatatatg atgaaattca agaagaaaaa gacattaaag
    43741 atgtaaatga a
//
LOCUS       DAMJWO010000029        43251 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.030, whole genome shotgun sequence.
ACCESSION   DAMJWO010000029 DAMJWO010000000
VERSION     DAMJWO010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43251
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.030"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            133..870
                     /gene="cas6"
                     /locus_tag="PC366_001580"
     CDS             133..870
                     /gene="cas6"
                     /locus_tag="PC366_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HDF2577110.1"
                     /translation="MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLESIRGSGLRKPLEFIPLNFKKRVLKEKIRGFKVREYYYINAYAGTFFLKGN
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            875..2350
                     /locus_tag="PC366_001581"
     CDS             875..2350
                     /locus_tag="PC366_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577111.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFYELLMDLKNELEKNDYKLKFT
                     CELNRNYLSLESAEYIDPKYISDYILENQLFKVFKNGKKETLEKIFSNIDNLTYVNFI
                     EELDKSSATEKQKEGIKKDFKNRRFPYVRNSGKYGLNTSLENMETNVKRIVDTVIKSN
                     IEIDEIDKLDLTQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKR
                     SGQVESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKS
                     FYKKLLHEKISSIRLYRFDIDTNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREP
                     GNTRNLGKKMIDNGNLSNLKELLLDNISVLRQLTGTSREMDFVSSSYNIGLYIKLCWI
                     VDGGEEYKMKNYMESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQT
                     IMHVLVSNGILIGEGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            2370..3383
                     /locus_tag="PC366_001582"
     CDS             2370..3383
                     /locus_tag="PC366_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HDF2577112.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYREKIHA
                     KTSIATITYDLRRMLHQEYGWNLSNIIFGKKGNIYPSIKQNVGCVDENGLETDVFGYL
                     IPLKDKGSISKASPLRIIPFRSLNSYRGSTQLITNRGFLSSEFGRKYYDEKEENEVLR
                     DENFPTSQALAIEETLSDYYVYTITLELDRIGVVEVEDGKLLLPEERKFMSKELREKA
                     VKDILDAITVFTRNIKHSSVLLKPLAVMGGAFDKVVPFFWDDVDYNADSGEINLEGVI
                     ETIESYSLKESNTILAINDKLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMWY
                     LKE"
     gene            3399..4205
                     /gene="cas5"
                     /locus_tag="PC366_001583"
     CDS             3399..4205
                     /gene="cas5"
                     /locus_tag="PC366_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HDF2577113.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYTNMRKGKDKEKFLLQGNYYDYY
                     KEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIKKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVELKEVMPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPY
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCNVCIDTKEVFTWL"
     gene            4232..6640
                     /locus_tag="PC366_001584"
     CDS             4232..6640
                     /locus_tag="PC366_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HDF2577114.1"
                     /translation="MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKDILEKMNLLEEDKLYIYKSIMLHHGNYEDYMRLSTSKVQEEIYDYIE
                     KGILEKEEFNLKDIESYINDILNVDFKFGEDVLDYDYIDKLSESMFIDSDYNNGQIDD
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDDMILNEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVS
                     FIKEKEIKSIVEGALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRF
                     KFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKNTTKNILKDILKTNSIFTMGIRKTILDDYYDNSVVK
                     NYFEENFISCDKEIKNIYGINKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            7081..8028
                     /gene="prmA"
                     /locus_tag="PC366_001585"
     CDS             7081..8028
                     /gene="prmA"
                     /locus_tag="PC366_001585"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HDF2577115.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQDGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK"
     gene            8047..8805
                     /locus_tag="PC366_001586"
     CDS             8047..8805
                     /locus_tag="PC366_001586"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HDF2577116.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICD
                     KNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEMILQKLTEV
                     GVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEAL
                     EDMKKNNVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            8807..10105
                     /gene="mtaB"
                     /locus_tag="PC366_001587"
     CDS             8807..10105
                     /gene="mtaB"
                     /locus_tag="PC366_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HDF2577117.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            10148..10498
                     /locus_tag="PC366_001588"
     CDS             10148..10498
                     /locus_tag="PC366_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HDF2577118.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            10661..10840
                     /locus_tag="PC366_001589"
     CDS             10661..10840
                     /locus_tag="PC366_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HDF2577119.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            10870..11313
                     /locus_tag="PC366_001590"
     CDS             10870..11313
                     /locus_tag="PC366_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HDF2577120.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            11424..11921
                     /locus_tag="PC366_001591"
     CDS             11424..11921
                     /locus_tag="PC366_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HDF2577121.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFI
                     WFINK"
     gene            12114..12677
                     /gene="raiA"
                     /locus_tag="PC366_001592"
     CDS             12114..12677
                     /gene="raiA"
                     /locus_tag="PC366_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDF2577122.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFY
                     MFRNQDNFEINIVYKRKAGGYGLIEQD"
     gene            12890..13126
                     /locus_tag="PC366_001593"
     CDS             12890..13126
                     /locus_tag="PC366_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HDF2577123.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            13139..14482
                     /gene="yqfD"
                     /locus_tag="PC366_001594"
     CDS             13139..14482
                     /gene="yqfD"
                     /locus_tag="PC366_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HDF2577124.1"
                     /translation="MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKEFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN"
     gene            14421..15536
                     /locus_tag="PC366_001595"
     CDS             14421..15536
                     /locus_tag="PC366_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HDF2577125.1"
                     /translation="MKIIVIKIVIIVKIIIAITTNKIKLKILGGLIQLIIQKKFTIAD
                     GNFERELFGNFDENVKLIEKTLNIDVILREGNIILIGEEKNVDSALKLMNELHQTVSN
                     GKHLDKQSISYSLSLLLEGSEQKIKELEGTIVITQRGKAVQPKTLGQKEYIKLIENND
                     ITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRIILTRPAVEAGESLGFLPGDLKDKVDP
                     YLRPLYDALFEMLGADKFNKYLERGTIEVAPLAFMRGRTLDNSFIILDEAQNTTSEQM
                     KMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLIQATEILKGVPGIGSIMLTDRDVVRH
                     ELVQRIIRAYEKHDKREEFKKEERKKVKMQEKTFKRK"
     gene            15593..16054
                     /gene="ybeY"
                     /locus_tag="PC366_001596"
     CDS             15593..16054
                     /gene="ybeY"
                     /locus_tag="PC366_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HDF2577126.1"
                     /translation="MDLILDDRQDKLEVSEELIEKIKDIIIECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            16060..16779
                     /locus_tag="PC366_001597"
     CDS             16060..16779
                     /locus_tag="PC366_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDF2577127.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            16898..17299
                     /locus_tag="PC366_001598"
     CDS             16898..17299
                     /locus_tag="PC366_001598"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDF2577128.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSGFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHSIKDLLPNYFSGNDLK"
     gene            17363..18256
                     /gene="era"
                     /locus_tag="PC366_001599"
     CDS             17363..18256
                     /gene="era"
                     /locus_tag="PC366_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HDF2577129.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            18268..19647
                     /gene="mgtE"
                     /locus_tag="PC366_001600"
     CDS             18268..19647
                     /gene="mgtE"
                     /locus_tag="PC366_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HDF2577130.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEEREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIIARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLREQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            19720..19875
                     /locus_tag="PC366_001601"
     CDS             19720..19875
                     /locus_tag="PC366_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HDF2577131.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            19841..20614
                     /gene="recO"
                     /locus_tag="PC366_001602"
     CDS             19841..20614
                     /gene="recO"
                     /locus_tag="PC366_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HDF2577132.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTISLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            20607..21206
                     /locus_tag="PC366_001603"
     CDS             20607..21206
                     /locus_tag="PC366_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HDF2577133.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            21366..22244
                     /gene="glyQ"
                     /locus_tag="PC366_001604"
     CDS             21366..22244
                     /gene="glyQ"
                     /locus_tag="PC366_001604"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HDF2577134.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            22244..24310
                     /locus_tag="PC366_001605"
     CDS             22244..24310
                     /locus_tag="PC366_001605"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HDF2577135.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQSDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKEEYIFATIKQDGKETSEVLKDILPETIKSVVFPKAMRWGGKNLKFARPI
                     RWIVALLNDKVLEFDLEGIISSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIAGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKVLIEHALD
                     NYSELDFNKEEVVEQIMNFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIRLYNEFKQVKVKVNE
                     LLKDKKYGIALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLEICDL
                     SKIVYK"
     gene            complement(24476..26023)
                     /locus_tag="PC366_001606"
     CDS             complement(24476..26023)
                     /locus_tag="PC366_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HDF2577136.1"
                     /translation="MDNFKKILLNELPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSQYQLNKIYEIAIKHNLDKIHLTTRQAIQLHDLSINSIVDI
                     MEEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEVFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEPYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEELFLEKFKEYYKLEKENGS
                     LELNIEEIDYSKPGVKIDIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLSTLLKELDN
                     VENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNEEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGIST
                     DAFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASSGNFYEWVNSNDNILNK
                     ITDKYKI"
     gene            26303..27070
                     /locus_tag="PC366_001607"
     CDS             26303..27070
                     /locus_tag="PC366_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDF2577137.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            27353..27550
                     /locus_tag="PC366_001608"
     CDS             27353..27550
                     /locus_tag="PC366_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2577138.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            27579..28655
                     /gene="vorB"
                     /locus_tag="PC366_001609"
     CDS             27579..28655
                     /gene="vorB"
                     /locus_tag="PC366_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HDF2577139.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            28658..29377
                     /locus_tag="PC366_001610"
     CDS             28658..29377
                     /locus_tag="PC366_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HDF2577140.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTIEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            29390..29929
                     /locus_tag="PC366_001611"
     CDS             29390..29929
                     /locus_tag="PC366_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HDF2577141.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIKVPVTEIAQNLGNEKAANICMLGAMVKSLDLFTKEEFESGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            30086..31144
                     /gene="buk"
                     /locus_tag="PC366_001612"
     CDS             30086..31144
                     /gene="buk"
                     /locus_tag="PC366_001612"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HDF2577142.1"
                     /translation="MKVLVINPGGTSTKISVFQDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFDDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKEGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVAEKVSYLAPIEIVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            31162..32055
                     /locus_tag="PC366_001613"
     CDS             31162..32055
                     /locus_tag="PC366_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HDF2577143.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIESISREIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMTNALL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPKCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            32085..33293
                     /locus_tag="PC366_001614"
     CDS             32085..33293
                     /locus_tag="PC366_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2577144.1"
                     /translation="MKYAKRMDMVKASAIRASQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEITQKVLNERGKFALAYGPTKGEDELLDLLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDIVVTENPSYLGAINAFRPYECDFLGVDTDDEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVNKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIRAEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            33317..34579
                     /locus_tag="PC366_001615"
     CDS             33317..34579
                     /locus_tag="PC366_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2577145.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFSTPVLGMRWVMISLGILSIVMCPVLWFVIKDVDIREDKEEEASEKMSAGDFM
                     TVLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFG
                     APFGGYCADKVKSPTKVLLPIYVFGIAVIILFLVLPASTPMTIFIALTFVVGILGYMG
                     KGIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIF
                     QIAILIIGILSCLYILKVKKKRESKLEA"
     gene            35155..36618
                     /locus_tag="PC366_001616"
     CDS             35155..36618
                     /locus_tag="PC366_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HDF2577146.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSMKLRFFQIKDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSILFSVVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVTSSIALGIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIIANINLVPGAIMTMFKSAFGFGSVFGGMLGSAISWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIIITGMYNVTDVYTTLPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKHEKHIIN
                     VCRFMLIICAAMCCFIEPLTSWALGDICIGVLTYINLVGIFTLKKPAIKAYYDYQRQK
                     KMGVKRSDRTFNPIELDIRNAEFWENRYLKEDKHELN"
     gene            36674..37810
                     /locus_tag="PC366_001617"
     CDS             36674..37810
                     /locus_tag="PC366_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2577147.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKISEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLVDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVDIFTKIMEEFGIYEDEQVMLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINSYAKDRVIDGIKILALTGFNLFENPELLKKMKEE"
     gene            38046..39161
                     /locus_tag="PC366_001618"
     CDS             38046..39161
                     /locus_tag="PC366_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HDF2577148.1"
                     /translation="METLEVRNIELSGTNYEIGYRLGELVANMPEIIEGQINKSNLVS
                     KKEEKEMIELFDKYCPGLNEELQGFADAIQVNCNQILYYTMTYLKPGCSQVALTPELT
                     ENGHVLFARNFDFSHNMEDFVLCKTKVNGKYAHIGTTVMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSDGLRKPAIVGLQFWAVIRYLLENCKDVDEALEYLKDMPIAYNINLLLADK
                     SGNIALVETLDGKKEVNIINSLESKREYFLHSTNHTHIDKLHKLEPQSMKNSIHRYKL
                     IKEYINKAKKIGEKELMNLLSLKYPNGLSCNYYNDFFGTLKSIVMDLNIGKFNILWGG
                     LENKWESYYLKNDIKSITQRININIEKAPSDFFDFIE"
     gene            39313..40182
                     /locus_tag="PC366_001619"
     CDS             39313..40182
                     /locus_tag="PC366_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2577149.1"
                     /translation="MDYLKYFEKAVMYIENNLHENITVNDVAKETGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVSSTKELLYSDKKVIDIAIGSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVGKKKKLELDFMRHLVGNITIKPVIKEIEKIKVIGIKDKVILENNSLPD
                     LWEKFRKVHHIVPNTLPSKRVFGICEAISEIHLVSESMEFNEIIGLEVNSYDVIPNSF
                     VSKTIKEGKYAIFTHTGSLDNLDKTYEYIWGTWFLSSKEELDIRDDFEVYDERFLGPS
                     NVNSQIDIYIPIK"
     gene            40374..41264
                     /locus_tag="PC366_001620"
     CDS             40374..41264
                     /locus_tag="PC366_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2577150.1"
                     /translation="MAKLTLEHIKGNTYYIPLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLSPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPSNGKIVDTELEAISLPGHYFEMIGVRTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKSLI
                     NINKKKMEEIIDNIKKVCYEPVMIDEVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKAV"
     gene            41482..43236
                     /locus_tag="PC366_001621"
     CDS             41482..43236
                     /locus_tag="PC366_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp23"
                     /protein_id="HDF2577151.1"
                     /translation="MYIMNKKFKKFSKKLSILILVLTMFLFNNLTANAQIKEDSIIGI
                     DRYETAGLIADRQTYDTVILVNGDKNLSDGLSSSGLAGAINAPILLTKKSEIPKATLN
                     RLDNKSLNVVKKVYIIGGYNTIENSVEKDIKRKGIQVERINGNNRIETSYNVAKKINE
                     VSSVKEVMLTNGFVGEADAMSIAPVVAKNKGAIILTDGKSVPFKTEGLNVYAIGGKSA
                     INEDLVNETKATRIGGNDRFETNKKVMEKFYNGATDFYITNGYQLVDALTLSPLAKEK
                     PIVLVADGSNKGILKGAKSITKVGGIDANIYKQCLDMIKYNNMDVTPNILKHLTSVEG
                     NEVSEILIESDNLGVVVEKTNTNKFEFDYVSVTNEKNCTFSVYKENSSNNVKNGKLVV
                     SAKKKIDKKDSDLQDMNGDNMINANKDRMVNVIKIGVPDKMYSNFKVDVESGSVELYN
                     IKGGATVDVNDGIANIVDNNVTNPFNINTNSGISGVTAETISSEIKFRANNGIVSVTA
                     TNINGNISLFGSDNKGTFDGIFKLNLKKEPSNLHLKLVGNGINKLPEGWSKDYILGNG
                     QPIIEVKNNGINNISIGE"
BASE COUNT        17365 a         4402 c         8002 g        13482 t
ORIGIN      
        1 acagtaaaat atatttaaaa aattaaaaaa caaaattaaa tttattatca aaaaatcatt
       61 ttatgatatg ttttattttt tatattacaa atagagaata atgaattata ctagaaagta
      121 ggaggtgaaa atatgagcag aatttcaatt tttatggagt catgtaatgg caaatttcca
      181 aatgaaaatt caatgttgtc agtttccttt ataaaaaata ttttaaatgc agaaaacaaa
      241 gattttgcta aaaatatatt taactatggg gaagaaagaa aaaacaataa gcaaataaag
      301 gatataaata cagccatcta cataccaaat cttataagaa gcaaaaatga gttgcttgtt
      361 gatggagata taatattcaa tataagtttt tataattatt ctatgttcag taaattatac
      421 aatggaattt taaaagtaaa ggagctagaa tataaaggtt atagatttaa aataaaaaat
      481 ataaaaatac ataaagaaca cgagataaaa gaaaatggtg ttatatttaa aactatgtct
      541 cctataatag taaagaataa agaaggtaaa tatttagatg tagaagattc aaattatata
      601 gaatgtttaa actatatagc taatctaact ctggagagta taagaggtag tgggcttaga
      661 aagccattgg aatttatacc tcttaacttc aaaaaaagag tgttaaaaga aaagattcgt
      721 ggatttaaag tgagagaata ttactatata aatgcttatg caggaacatt ttttttaaaa
      781 ggaaatatgg aagatttaaa tgcactgtat aaaatgggaa ttggatatag aaggacggaa
      841 aatgcaggaa tggttgatat attaaagtag cgaggtgaga gaaataaaag ctaaatttta
      901 tagatcaggt gatattgtaa gagatattgg cattgtttac ttttatgaat tactaatgga
      961 tttaaaaaac gaactagaaa aaaatgatta taagctaaaa tttacttgtg agttaaatag
     1021 aaattattta tctttagaat ctgcagaata tatagaccct aagtatatat ctgattatat
     1081 attagaaaat caacttttta aggtatttaa aaatgggaaa aaggaaacct tagaaaaaat
     1141 atttagtaat atagataatt taacgtatgt aaattttatt gaagaattag ataaatcttc
     1201 tgcaactgag aaacaaaagg aagggattaa aaaagatttt aaaaacagaa gatttccata
     1261 tgttagaaat agtggtaagt atggattaaa cacgagttta gaaaatatgg aaacaaatgt
     1321 aaaaagaata gtagatactg taattaaatc aaatatagag atagatgaaa tagataaact
     1381 tgatttgaca caatatgaag aaaaagatag tgtatgtaat gtttgtaata taaataaaac
     1441 aacaaaacta gatattgatt taagagagcg aaaggactct aagtataact ttttatttag
     1501 aggtgcagaa aaatcaggct ttaaaagaag tggacaagtt gaaagtaata tttgttttga
     1561 gtgtgaattt ttcaacttaa tgtgtctttt atatataaat ttaaaaagac caatggtttt
     1621 tgcatatacg aatgatttaa gggaattagc atttttaaat cataagataa tgcttaaaag
     1681 aaagatgtat tcagataaat cattttataa aaaacttttg catgaaaaaa taagttcgat
     1741 tagactatat aggtttgata ttgatacgaa taaaggtata attctaaagt ttgactctat
     1801 tatagagtat aaagaattat taaaaaaaat tgaacttata gatattatag ataattataa
     1861 tttttcaaga gagccaggga atactagaaa tttgggtaaa aaaatgattg ataatgggaa
     1921 tttatcaaat ttaaaagaat tattacttga taatataagt gttttaaggc aactaactgg
     1981 aacttctcga gaaatggatt ttgtatctag ctcatataat atcggtttat atataaaatt
     2041 gtgttggatt gtagatggag gggaggagta taaaatgaaa aactatatgg aaagtaattt
     2101 aatatattca agagtaggta aagacttatt taataaaatg acagatgaat ccagaagaaa
     2161 aaatttttct atgaaagtga ttcaactact taagtctaat gatagaactc agctatttca
     2221 aactataatg catgtgttag tttctaatgg aatcttaata ggagaagggt ttgtagaagg
     2281 tctaatgcag agttctgaat tagaattaaa tacgaatgta ggtctattta ttcaagaaat
     2341 catgaaataa aaaaggggga aaatttaaaa tgaatgaaaa aagagtaaaa ggagtaacat
     2401 taactatact gacagaaagc ccagttccac tttcatatga ccaagggtat ggaaattata
     2461 caccaataaa aaaagaacaa tatagagaaa aaatacatgc aaaaactagt atagccacaa
     2521 taacatatga tttaagaaga atgctccacc aagaatatgg ttggaattta agtaatatta
     2581 tttttgggaa aaaaggaaat atatatccat ctattaagca aaatgtagga tgtgtagatg
     2641 aaaatggatt agagactgat gtatttggtt atttgatacc acttaaagat aaaggttcta
     2701 taagtaaggc ttctccgctt agaataatac cttttaggtc attaaattca tatagaggtt
     2761 caacacagtt gataacaaat agaggttttt taagtagcga atttggtaga aaatattatg
     2821 atgagaagga agaaaatgaa gtacttagag atgaaaactt tccaacatca caagcattag
     2881 caatagaaga gactttatca gattactacg tttatacaat aacattggag cttgatagaa
     2941 taggagtagt agaagtagaa gatggaaagt tgcttttacc agaagaaaga aaatttatga
     3001 gtaaggagtt aagagaaaaa gcagtaaaag atatattaga tgcaattact gtgtttacaa
     3061 gaaacataaa acattcatca gtactgttaa aaccacttgc agtaatgggt ggagcttttg
     3121 ataaagttgt accgtttttt tgggatgatg tagattataa tgctgatagt ggtgagataa
     3181 atttagaggg agtcatagaa actatagaaa gttatagcct taaagaaagt aacacaatac
     3241 ttgctatcaa tgacaaatta aaaatttcta ataaaaagga attaaataag tttaatttaa
     3301 gtaaataccc tgtaaaagag attaaaaatc tagcagatag attggaaatt ggagaagata
     3361 atatgtggta tttaaaagag taggaggttt tttgaattat gaaagtatta caatgtaaac
     3421 ttaagcaacc aactgctcac tatagagacc caaaagtatt tcaaaatgaa tatataagta
     3481 ctttaaattt accatctaag accacaataa tgggaatgat aacgtattta tgtgatagaa
     3541 gattaaactc tgatatagat ataggaataa ttggaacaca tcatcataga gaactagaat
     3601 tttcaagagg agagaacatt gatttttgga atgaatatac aaatatgaga aaaggcaaag
     3661 ataaagaaaa gtttttgctt caaggaaact actatgatta ctataaagaa cataaagctc
     3721 aaaatagcat attaaactat gaagttctta aagaagtaga actgactata tttatttctt
     3781 gcaaggatga tgaagaactt gaatttatta aaaaaaagct tgaaagtcca tgtaaatatg
     3841 caaatttagg aagaaaagaa gattttgtaa taccaagtga aaaagggtgt tttgtgaaag
     3901 aagttgagtt aaaagaggtt atgcctatga atactcgtga tgctataaaa gaaaatataa
     3961 aattaaagaa tacatatgta agagttgact taagagataa agagaatgtc gagactataa
     4021 taaatcaagg tgtattgatt gcattacctt ataaatataa agatttagaa gcaaatagag
     4081 atgatagagt ttatgagttt tgccattata tatatgttga taatgatggt atatatccta
     4141 aaaatattaa ggtaaatgta tgtaatgtat gtattgatac aaaagaagtt tttacatggc
     4201 tttaaattat tttgaaagat aggtgtttat catgaaaaat atcatgcaaa aagaaatatt
     4261 agctaagtca tataatttaa gaactaatca acaagaacaa acattagttg aacatattaa
     4321 ggatttattt gaagtattag aatctatatt agaactaaat ctatattcag ataaagatgt
     4381 agagatacta aaaatatgtt gtgctttgca cgatttagga aaaattaatt caattatgca
     4441 acaaaaaatg gagattaata ataaaatatc gtatagttgc tcagaagaag agaggaaaaa
     4501 gttagagtct gacaaaaaat ctttaaaaaa gatagcaaga cacaatatat tttctggagc
     4561 atttttaaaa gatatattag aaaaaatgaa cttgttagaa gaagataagt tatatatata
     4621 taaaagtata atgttacatc atggaaacta tgaagattat atgaggttaa gtactagtaa
     4681 agttcaagaa gaaatttatg attatattga aaaaggcatt ttagaaaaag aagagtttaa
     4741 tctgaaagat atagaaagtt atataaatga cattttaaat gtagatttta aatttggtga
     4801 agatgtattg gattatgatt acatagataa attaagtgaa agtatgttta tagacagtga
     4861 ttataacaat ggtcaaatag atgattcagt tttaaattat agaaagttta agtatatttt
     4921 atataaaggg atgctgaact taatagacca tagtgcatca agtagacaga aaggtataaa
     4981 attttataac gattttactg atgaagaaat tgatgatatg attttaaatg agatatataa
     5041 gagtcagggt aatttagaaa aaaataatat agagttcaat actatacaaa aaaggttgag
     5101 agaactttct ggaagaaatg ttctgactgt tgcatttaca ggttcaggaa aaacagctgc
     5161 agattataga aagactttta aaagaaaatt ctttttagtg ccaaataaaa tatcagcaga
     5221 aagtttttat agaaaaaata tttttcaaaa taaaaatgat ttagatacaa gaagtagtaa
     5281 tgattacatt ggattacttc atggagatat aaacttatat tcagagaatg aagataatgg
     5341 agaacatgat tttgtattga cattaaggga tatagatttg agtataaatt tttgtaaacc
     5401 ttgtgtaatt gcaacagttg accagttatt acttagtatg tttaaatttc cgggatatga
     5461 aaaaatattc gcagccgtaa aaaatgcatc tataactgtt gatgaagtac atttattgga
     5521 accaaagatg tttttgattt tgatatattt tatgcagttt gcatgcaagt acttagatgt
     5581 tgattttcac ttaatgacag ctacacttcc aaaatcatat aaagagcaaa tgataaacaa
     5641 gggaattatt tttcaagaag aaagtaatga aaatgttact gataaaggag aaatagtttt
     5701 tattgagagc aacaaggaag aagaaatttg tgaaggtaaa gatgtaaagg tttcttttat
     5761 aaaggaaaaa gaaatcaagt caatagttga aggtgcttta gaaaataaac aaaaaattct
     5821 tataataaag aatactattg attcagtcaa tagaacatat gagtttttaa aagaaaattt
     5881 atctgataag tatggtggtg tagatataga tgttttacat agtagattta agttcaaaga
     5941 taaaaaagag aaatatagta aaatattaaa tggagagggt gatatttgga tatcaactca
     6001 atcagtagaa atatccttgg atttggattt caatataata ataagtgatt tagcaactat
     6061 ggatagctta atacaaagaa tgggtagatg caatagaaat aataaatatg aatatggaaa
     6121 cttttatatt ctacctagtg aagataaaat ttatgataac aaacttaaga acacaactaa
     6181 aaacatctta aaggacatat taaaaactaa ctctattttt acaatgggga ttagaaaaac
     6241 tattttggat gattactatg ataatagtgt agttaaaaac tattttgaag agaattttat
     6301 aagttgtgat aaagaaatta agaatattta tggtataaat aaagaaattt ttgatggatt
     6361 ggatttaatt tttaattttg aaccttacaa aaatattgtt gatagtaaga aggaagcagc
     6421 taaaattttt agagatgttg atgttagtta caaaattatt ctggaagaag atttttataa
     6481 ggaagatagg gagttacaac aagattcgat tcaagtatca gggtttatat ttaatagatt
     6541 atattattat ggattaataa gcaaagtaga aggatacatg gtactaaaat ctagtagtaa
     6601 gtttgagtat aatagtactg taggcttaat tttgaagtga gcatatgttt aaatataata
     6661 tacctttaga cattgaaaat acaaaaagta ctactgtaag cccactgtaa aaactatttt
     6721 ttaaaaggaa aaataagttg tgagatagag tgtctacaag tgtatataga taataaattt
     6781 gaggtttaag attaactaag tgggtttcag gtacatcgcg aaaataatta taagttggag
     6841 attttgtatg tttaagatta actaagtgga tttcaaatat tgatatagta gatataatag
     6901 aagttttatt attaggttta aaattaacta atcggatttt taaatattct gactattata
     6961 taaggatatt attagcttga atttaaaacc aataatataa aacaacaaaa tattatattt
     7021 atgatataat aaaagttatg gaaaaacagg aatattacta tagagaagag aggtaaactt
     7081 atgaataatt ggatagaagt aactataaaa acaacaacag aagcagttga acctataacg
     7141 aatatactat atgaacaagg agctggagga gctgtaatag aagacccaaa agacttttta
     7201 ttccaaaaga aaaatgaact agactgggat tatgttgaag aagaagtatt taaaaagaat
     7261 gaagaagatg atgttcttat aaaaacttat gtttctgaag aaaaaaatgt gatggaattt
     7321 gtcgaaataa taaagcaaaa agttttagga ttaaaagatt ttggtataga tataggtgaa
     7381 ggaagtgtat cattggacca agtaaatgaa gctgattggg caaatgcatg gaaagcatac
     7441 tacaaaccaa caaaagtagg acaaagggta gtagtaaagc ctacatggga agattatgct
     7501 atgcaagatg gggatttaat catagagctt gaccctggaa tggcatttgg tacagggaca
     7561 catgaaacta ctagtatgtg cattagagaa ttagaaaagt atgtgaataa agattctaaa
     7621 gtatttgata ttggatgtgg tagtggaatc cttgcaatag cagcagctaa attaggagca
     7681 aaagaagttg tagctgtaga tttagatgaa gtggctgtaa aagttgcaaa agaaaatgtt
     7741 cttgaaaata aagttgaaaa aagtgtatct gtaatgcatg gtaatttaac tgatgtaata
     7801 aaagataaag cggatgtaat agttgcaaat ataatagctg atataataaa gatacttgca
     7861 aaagatgttc aaaactttat gaaagaagat gctatattta tatcttcagg tataattttg
     7921 gataaagtag aagaagttaa agaaagctta attgaaaatg gatttgaaat agttgaagtt
     7981 caaaaattag gtgaatggtc agcaatagtt tctaagctta aaaaataagg gatatggtga
     8041 cgtataatgg atagattttt tgttgaaaaa aataatataa atctacaaga taaaacttgc
     8101 actatagaag gtgaagatgt aaaacatatt tcaaaagttt taagatgcaa actaggtgag
     8161 aaacttgaaa tatgtgacaa gaataataat gagtatattt gtgagataat gaatatagat
     8221 aagagtatag ttaatttaga gattttagaa aaagttgata taaatagaga atcagaactt
     8281 aaagtaaggt tataccaggg acttccaaaa gctccaaaaa tggaaatgat acttcaaaaa
     8341 ttaactgaag tgggtgtaga agaaataata ttagttcaaa ctaagagaag tgttgttaaa
     8401 gttgatgaca aaaaagaaga taaaaaattt gaacgttggg aaagaataat ttatgaagca
     8461 gcaaagcaaa gcaaaagagg taagatacca aaattaagag gtgttttaag ttttaaagaa
     8521 gctttagaag atatgaaaaa aaataatgta aatatttgcc cttatgaaaa tgaaagaaca
     8581 gtttcaataa aacatgcact aaaaaaatgt gattctaata tagatagtgt tggaattttt
     8641 ataggtccag aaggtggatt ttctgaagaa gaaatagagc aaatacaaaa aaataattgt
     8701 aatgttgtat cattggggcc tagaatatta agaactgaga cagcttctgt tgtagcatca
     8761 acaatagctt tgtatgaact aagtgattta ggaggagaaa aataaattga aaaaagtagc
     8821 tttttataca cttgggtgta aagttaatca atatgaaaca gaagctatgc tagaactatt
     8881 tgagaaagat ggttatgaac aagtcaatag tgaagagtat gctgatgttt atgttataaa
     8941 tacatgtaca gttactcata tgagtgatag aaaatctcgt caatatataa gacgagttaa
     9001 aaagaagaat ccagatgcaa taatagccgt tgtaggatgt tattctcagg tatctccaga
     9061 agaaattttg gatatagaag aagtaaattt agtcatgggt acaaatgata gaagaaagat
     9121 tgttgaagaa attaaaaaga taaattcaag taagaaagtt agtacagttg atgacataat
     9181 gaaagttaaa gcttttgaag aaatagaaat cagccaaact aatggaaaga ctagagcatt
     9241 tatgaaaata caagatggat gtgacagatt ttgtacttat tgtatcattc cttatgcccg
     9301 aggacgcgtt agaagtagag atattgatag tatagtcgat gaagtgaaaa aattggctaa
     9361 taatggctat aaagaggttg tattaacagg aatacatgtt gcctcttatg gaaaagattt
     9421 aaaggatagg gatattaaac ttcttgatgt aataaaacaa ataaaccaga tagaaaaaat
     9481 agaaagaatt aggcttagtt ctgttgaacc aattttattt acagatgaat ttgtaaatga
     9541 agttttaaag atggataaag tttgtcctca ttaccattta tcacttcaaa gtggatgtga
     9601 tgaaactcta aaaagaatga atagacgata cacaacttta gagtacaaaa ctattgtaga
     9661 tagattgaga agtaaaatgc cagatgtggc aataactaca gatgtaatag taggttttcc
     9721 tggagagaca aatgaagagt ttaaaaaaac gtacgagttt ttaaaagaaa tagagctttc
     9781 acaaatgcat atttttaaat attcaccaag aaaaggaact ccagctgcaa ctatggaaaa
     9841 tcaagttgac cctcaaatga aacactttag aagtgaacaa cttttaaatt taagtaaagt
     9901 aaattttaat aaatttgcaa ctaaatttat cggccgtgag ctggatgttt tgtttgaaca
     9961 aaatatagaa ggcaataaat atgagggatt aacttcaaat tatataagag ttgttgttga
    10021 aagtgacaaa aatatacaag gtcagatatt aaaagtgaaa ataaatgatg taaaagatga
    10081 atatgtagaa ggaattttgc tataacatgt agaaattata atatttataa gataggaggt
    10141 ggaaagaatg gattgtattt tttgtaaaat agcgaacgga gaaatacctt caactaaagt
    10201 ttatgaagat gatagagtct tagcttttaa tgacttgaac ccagttgctc catatcatat
    10261 attagttgta cctaaaaaac attatgatag tttaattgat attcctgata aagagatgga
    10321 cattgtgtca catattcatg ttgttattaa taaaatagct aaagagaaag gttttgacca
    10381 aactggattc agagtcataa ataattgtgg aagtgatgga gggcaagaag ttaaacattt
    10441 gcactatcat attttagctg gtaaaaagct tcctaattac gaagcgggac aaaactaaac
    10501 taaattattg aaaaattgag ttccttcttg ataaaaatac ttgataaaag taaaaattta
    10561 gtttataata aacaaagtgt taggttgtaa tgcatattat gcaaaaagaa catagttaca
    10621 gtcccagcat aattgcgcta ttggagggag ggaaaaagaa atgtcagaag taagagttag
    10681 agagaatgaa acattagaca gcgctttaag aagattcaag cgtcaatgtg caatgtctgg
    10741 catcatgtca gaagtgagaa aaagagagca ctatgataag ccaagcgtta agcgtaagaa
    10801 aaaagctgaa gcagcaagaa gaaaaaacgc taagaaatag tagtaaataa gaataaagag
    10861 gtgaagggga tgtcccttaa gcaaaagtta caagaggatt tgaaatcttc gatgaaaaac
    10921 aaagatacag tgagaaaatc tgtagtaact ttaataagag cttctataaa gcagtatgag
    10981 gttgataata gggtcgagct tgatgaagat ggaattatcg atgtaatagc aaaacaattg
    11041 aagcaacgta gagatgcatt agttgaattt gaaaaagctg gaagagaaga cttaataaaa
    11101 gaaacagaag gtgaaattga agttttaaaa gagtacctac ctcaacaatt aagcgaagaa
    11161 gagttagaag aaattgtaaa atctactata tccgaagtag gggcaacttc tatgaaggat
    11221 atgggaaaaa taatgtcagt tatccaacca aaagttaaag gaagagctga cggaaaactt
    11281 ataaataagt tggtaaaaca aaacttacaa tagattgata tagcctagag agaaatctct
    11341 aggcttttta tagtttttgg gaataacgag tcatatttga gcatatctat aatcaaagaa
    11401 aattttgaaa gaaggggaaa aatttgatta tatcagtaaa agagattagg aattttttga
    11461 taaacatatt tataccacta ataataggtt acttaagtag catcttaaca atgattatca
    11521 gtggaacaga tatttcaacc tattatttac aactcacaaa gccaagcttt gcaccaccag
    11581 cttttatctt tcctatagtt tggactatat tgtacatatt gatgggtata tcttcatacc
    11641 taatattaag aaagggttac aacttaccta aggtaagaga tgcaattttt tattatggat
    11701 tacaacttgt attaaacttt atttggagta tactattttt tggatttgga cttagattta
    11761 cagctttgat agatataata ataatgattt tggtttctat aataatgatt tcgaagtttt
    11821 ctaaaataga taagagatct ggatacataa atttgattta tttaatgtgg cttgtttatg
    11881 caggattttt gaactatttt atatggttta ttaataaata gaatgtaaag attttgtaaa
    11941 ttaccctgta cttttaataa tatcataaca aacgaaaaat aaatagacta ttaaaaataa
    12001 tcattttcat atacaataat attaatttaa atacaataaa tttataaaaa ttgtatttaa
    12061 agattaacat attaaagtat tagaattgga aaggcttgaa gggagaggtt tttatgcaaa
    12121 taatagtatc tgggagacaa atgaaattaa ctgacggaat aaaaggatac gtagatggaa
    12181 aattaagtag gttagaaaaa taccttgatc ctgaatcaga agtgaaagta acagtaagtg
    12241 cgaaaaagga tagacaaaaa gtggaggtta caataattcc tattaacggt caaataataa
    12301 gagcagaaga tgtagaagat gacttatatg cagcaattga tattgtttgt gacaaattaa
    12361 gtagacaagt tgtcaaatat aaaactaaag ttaaagacaa agttcaaaat aataagagca
    12421 taagatttga aaatcttgac tttatagata atagcagtga atttgatgat tatgattatg
    12481 atgatgaaga agatgaaaat atagtaatag aaagaagaaa gaaatttaat gtaaaaccta
    12541 tgagttctga ggaggcgata cttcaaatgg aactagtagg acacaatttc tatatgttta
    12601 gaaaccaaga taattttgaa ataaacatag tgtataagcg taaagctggt ggatatggtt
    12661 taatagaaca agattaataa aaattgtata cgtttagatt ttatataaga aaaaataaaa
    12721 aggtaatcat gttgattttt tatcaatatg attacctttt tattgtttaa ataatatatt
    12781 agatattagg tatttattat ataaaaattt taaaactaat ctgttacaac atcaataaag
    12841 tgcataaata cctatttcaa gcataaaatt aattaagggg gtaatgctta tgttagaaat
    12901 atccactgat ttacaagtaa atcaaccagt tattactgtt acaagtaata cgtttattag
    12961 tatagaaaat tatctatcaa tattagaata tgaagttgat ttaataagaa taaagactaa
    13021 agttaaaaca attaaaatat ctggggataa actttcactt aagtatatta ctgatagtga
    13081 gataggtata aaagggatta tctacaatgt tgagtatgtt gattaggagg agatacactt
    13141 gataagtttt ataaggggat actatgttat agttgtggaa ggagtaggac tcgaacaatt
    13201 tttaaatcat cttataagaa atgggataag tgtttacaat gtaactagaa taaaaaatac
    13261 taaaatggag tttcatatag atagacaaga tataaaagaa tttaagaatg tttatagagg
    13321 aagtaagttt gatataaagg taaagcaaaa aactggggtc ccttttatta tcaaaagagt
    13381 ttataagcac aaaggtatgt ggatttgtgc tcttgtttct ttatttttat tgatgtctac
    13441 atcgcagttt gtgacagatg tatatataca atctcctgaa ggtataaaaa aagaagctct
    13501 tagaaatgag ctttataagg ttggagtaag accaggagtc tataagaaga gtattgatag
    13561 aaaagaagtt agagaccata tgatgtcaaa atttaatgat gtggcatatt tatctatcaa
    13621 tgtaaaagga acaaatatat ttgttactgt tacaaaaaag gcagaatccc taaaatctac
    13681 agaccaatca aattattgta atgtaattgc tttaaaaaat ggtataatag aaaaggtaat
    13741 ccctagaagt ggtaaatcag ttattaaatc tggagacata gtccaaaagg gagatgtctt
    13801 attaaatgga gctaatacca agtcaatacc agaagtatgg gcaagtactt tttatgagtc
    13861 cacaaaaaag gcaagttatg tagatactgt aaataaaaaa actggagaaa agaaaaatat
    13921 atatacacta agtttttatg ataaagagtt tacaatgaga aaaaatataa aatataaaga
    13981 ttatgttgtt gaaaataaag aaaaaaaact atcaatagga aactatactt ttccaataaa
    14041 gataaaaacg agtacttttt atgaaacaaa aaaggttgaa gtaaaaagga ataaagaaga
    14101 gttaaaaaaa gaattatctg aaaaagcttt aaaagagtta gaatacataa tcccagcttc
    14161 ggctagaata atagatgtaa aacataactt taaggttaat aaaaatatgt tagaatattt
    14221 aataacagtt caaactagtg aaaatattgc taaaatttat cctcttagta agtcagaagc
    14281 agaaaggttt ataaaggaag aaagtaaacc agatgaaggt gaagaggaag ttccttccaa
    14341 tccagaaaaa agaccattaa atgatataag aaatgagttt gatgaggata ataaggataa
    14401 taaagaccaa aacaattctg atgaaaataa tagtaatcaa aatagtaata atagtcaaaa
    14461 taataatagc aataacaact aataaaatta aacttaaaat cttaggagga ctaattcaat
    14521 tgataataca aaagaaattt acaatagcag atggtaactt tgaaagagag ttatttggca
    14581 actttgatga aaatgtaaaa ttaatagaga agactttaaa tatagatgta atacttagag
    14641 aaggcaatat aattttaatt ggagaagaaa aaaatgtaga ttctgcatta aaacttatga
    14701 atgaattaca ccaaactgta tcaaatggta agcatttaga taagcagagt atttcttatt
    14761 cattatctct tttgcttgaa ggaagtgaac aaaaaataaa agaacttgag gggacaatcg
    14821 tcataactca aaggggaaaa gctgttcaac ctaaaacttt aggtcaaaaa gaatatataa
    14881 aacttataga aaataatgat ataacttttg gtgttggacc tgctggaaca ggaaagactt
    14941 atcttgcggt tgctatggca gtaaaagctt ttaaaagaga tgaagttagt agaattatac
    15001 ttacaagacc agctgtggaa gcaggagaga gtctaggttt tttaccagga gatttaaagg
    15061 acaaagttga cccatattta agaccactat atgatgcctt atttgaaatg ttgggtgctg
    15121 ataaatttaa taagtattta gaaagaggta ctattgaggt tgcaccactt gcatttatga
    15181 gaggtagaac acttgataat tcatttataa tattggatga agctcaaaat actacttctg
    15241 aacaaatgaa aatgttttta actagacttg gatttggctc taaagctgta gttacaggag
    15301 atgtaactca aacagattta ccacaaaata agaagagtgg tctaatacaa gctacagaga
    15361 tccttaaagg tgttccaggt attgggtcta taatgctaac agatagagat gttgtaagac
    15421 atgagttggt acagagaata ataagagctt atgagaagca cgacaaaaga gaagaattta
    15481 aaaaagaaga acgtaaaaaa gtgaaaatgc aggaaaagac tttcaaaaga aagtaaaagt
    15541 gtagtaatat agatatatag cattattaat gaataaaaag taggtgtagt gaatggattt
    15601 gatactagat gatagacaag ataaattaga agtaagtgag gagttaattg aaaagataaa
    15661 ggatataatc atagaatgtt tagattatga aggatatgat gataattatg aagtgagtct
    15721 ttcttttgta gataataaag agattcatga attaaataga gaatatagag gagttgatag
    15781 agtgactgat gttttatcat ttcctctttt aagtgatgat tttgaggatg ttgagttaga
    15841 agaagaatcc ctaggtgaca tagtagtatc tcttgaaaga gccttagaac agagtataga
    15901 gtataaccat agttttgaaa gagaagtatg ttttttaata tgtcatagta tgtttcatct
    15961 tttaggttat gaccacgata cagatgaaaa tacaaaagaa atgagagaaa aagaagaaca
    16021 catattaaat aagttaaaca taacaaggga gtagttttta tgaaaccaga aaaaactcgt
    16081 caaggtataa ttaaagcatt taatgcagct atagaaggga tattgtatac atttaaattt
    16141 gaaagaaata tgaaaataca ttatttaggt tcagttgctg ttcttataat aagtttgttt
    16201 tttaactttt caaaattaga aatgataatg ttacttatgt ccatatgctt agttgtagtt
    16261 gccgaaatgt ttaatacagc tatagaaaaa gctgttgatt tagtaactga tgaatatcat
    16321 gttcttgcta agatagcaaa agatgttgca gctggaggcg ttctagtggc agcactaaat
    16381 tcagtagtag ttggatatat tttgttttat gataaattga cagatatatc tggaatatta
    16441 atttataaaa taagagaatc agaattacat ataaccttga tatgtatatt attggttctt
    16501 atagctgttg tagttgtaaa agcattgact tctacaggta ctcctctaaa aggaggaatg
    16561 ccaagtggtc atgctgcctt agcatttgct atagcaactg caattacact tatgactgaa
    16621 agagttgttg cctctactct tgcatatata atggctgtat tagttgccca aagtagaatt
    16681 gaaggaaaaa tacatacctt ttgggagact attgctggag ctttattagg tgtgttgata
    16741 gctatattag tatttcagct tggaatgttc tataattaaa ataaatgtac ataaaatatt
    16801 taaaataaaa caaatctgtg ctaattaaat ttttatgata taatgtagag tattaaataa
    16861 aaataacttt taattattgt atacaggagg agttgttgtg gataacatag aattgttaag
    16921 gttggcagaa gatgccagac aacattctta tgctccttac tcaggtttta gagtaggtgc
    16981 agctctttta actaagagtg gtaaagttta tactggatgt aatatagaat gtgcatcatt
    17041 aggtggaaca aattgtgcag aaagaacagc tatttttaaa gcaatatcag agggtgataa
    17101 ggatatctat aaaatagcta tagcaagtga taactcagaa aataatgagc aaacatatcc
    17161 atgtggaata tgcaggcagg taattataga gtttggttct gatataaaaa taataacggg
    17221 atatactaaa ggagaggtgt ttgagcatag tataaaggat ttgttgccaa actatttctc
    17281 tggaaatgat ttaaaataaa tttaaaagta taaataaatt taagtaatta aaacaagaag
    17341 ataaaaagtt aggagacagt taatgttcaa atcaggtttt gtcagtatag tgggtagacc
    17401 aaatgtagga aaatctactt taatgaataa tgtagttgga gaaaaaatag ctataatgag
    17461 tgataagcct caaactacaa gaaatacaat acaagcagta tatacagatg aagaaatgca
    17521 gatagtattc ttagatacac ccggtattca caaaccaaaa aataaattag gtgaatttat
    17581 ggtaaaggca gcaacagaag cttttaaaaa tgtagattta atattatttg tagttgatga
    17641 ttctaaaaaa ataggtcctg gagatagaaa gataatagag gatttaagaa gtgttaagac
    17701 accaataatt ttagttgtaa acaaaataga ccaactagac caaaaagatg agctatttga
    17761 tataatcaaa atgtatgata gagaaggtat ttttaaagaa atagtaccaa tatcagcatt
    17821 aaaaggaaag aatacggata ccttaataaa agttatacaa aattatttag aagaagggcc
    17881 aaagtatttt ccagattata tgattacaga ccagccagaa agagtattaa tagcagaact
    17941 tataagagaa aaagttcttc actatcttaa tgatgaaata cctcatggtg tagctgttga
    18001 aattgaaaaa atgaaagcga gaaatgataa ggaaatagta gatgtatctg ctgtaatata
    18061 ctgtgaaaga gattcacata agggaataat aataggaaaa aatggtagga aactaaaagg
    18121 aataggtaag tcagcaagac aagatataga attgctttta ggttcacaaa taaatcttca
    18181 attatgggtt aaagtcaaag aaaattggag aaatttacaa aattatataa ataattttgg
    18241 atataatgat aaataaaggt gggttatatg gataggaaac tggatgcttc ccaagattta
    18301 ttatatgaag taaaatcatt aattgataat aataaagtat tggagttaag agaattaata
    18361 gaggaatatc atataattga tatattcgat ataatggaaa atttagagga agacatgaaa
    18421 attcaattat ttgaagtact tcctttagat atggcatctt ctatattaga agaaggtagt
    18481 gtagagtttt ttattagtat tttatctaaa ctggatgtag aacactcgaa aaatatactt
    18541 gaacttatgt ctcttggaga tatggcagac aagttgagtg aacttgaaga agaagaaaga
    18601 gaacacataa taaatctttt gaatcaagag aatgccgatt atgtaaaaga gttactattc
    18661 tatgatgaag attctgctgg tggaacaatg accactggat atatttctat aaataaagat
    18721 atgacagctc ttgaggctat agaccatatg agagaagaag ctgaagaagc tgaaactatt
    18781 tattatatat atgtggttga tgatgaagaa aaactagttg gagtattgtc attaagagaa
    18841 ttaataatag ctagagacgc aaatatagta gaagatttga tgagtgaaaa tataatctct
    18901 gtttatgtag atgaagatag agaagaagca gtaagattag tatctaaata caatttaata
    18961 gcaattccag tagtagacag acaagaaaaa ttaaaaggaa taataacagt agatgatata
    19021 attgatgtaa tggaagaaga agcaactgaa gatatgtata aatttgcagg aagttcagaa
    19081 catgaaagag aagttgctga aaaagaaaac cctacattga gagagcaaat aatatcagca
    19141 cttagaggac gattaccttg gttaattatt accttggttg gagggttgtt ggcttcgtta
    19201 atactttcta acttagacta tataatgaat cctgtatatg ctccattagt attttttata
    19261 cctgtagtaa ttggtatggg tggaaatatt ggaactcaat catcatctgt tacagtaata
    19321 acattatcta ataaggattt aaattttagc aatgtggtta gagaaggtat tgtaggtatt
    19381 attacaggtc ttttgtgtag tataataaca ggtattgtaa tttactttgt tatgagaaag
    19441 ttagacattg tattaattgt ttcaatatca ttatttataa atatggtttt aggtgcaaca
    19501 ataggtgcgt ttatgcctgt tttattaaaa aaaatggatg cagacccatc tacagtttca
    19561 tcaccaatta tatctacagc tcttgatata actggtatag cagtttactt tataataaca
    19621 acggcattat tgtcaaaaat tgtttaataa ctttatgtat gatttatcct cttcttacta
    19681 aaaatataag tataaatgta agaagggggt tttttaaaaa tgaacaatat cagttgggaa
    19741 gtttttaaaa aaacaggtag tatagatgca tatttatatt tctgtgattg caaaaacata
    19801 catgaagaaa ttgaagaagt aagggagaaa aaagaagacg atgataatcc tgaacaccca
    19861 ggggatagta cttaaagcta taaggtataa ggaaagtgac ataatactta cactatttac
    19921 aagaaagctt ggaaaagtat ctgcaatagc aaaaggagct aaaaaaaata agagctcttt
    19981 gctttcatca tcacaattat tttcttatag caattttacc ttaaaaaaac aaggtaatat
    20041 gtacaaggtt actcaaagtg aaataataaa aagtttttat aatatatcct atgatataga
    20101 ggcattttct tatgctacat atattacaaa attagttgaa aattctatac ttgaaaatca
    20161 gactaataat aggctattta tattacttgc gcagactctg tatttgtata cacaggataa
    20221 tacagacaat aggtttataa cagcagcatt cgagttaaaa tttttagact atataggatt
    20281 taaacctata gtaaataaat gcattaattg tgaatgtaaa attttacaaa attctgtgtt
    20341 taatatctac gaaggtggta tactatgtag taagtgtagt aaactttttg ataataatat
    20401 aaaattagac ttaacaacta taagtcttat ggaatatgta ttaagaaatg atattttaac
    20461 atgtagtaaa gctaaagtat caaaatatat aacacatgaa cttgagaata ttctagacaa
    20521 gtatttgaaa gtttatgttg ataatattaa ttttaaatca ttacacgtat tgcaaagtgt
    20581 aaaaaataat aagggagtgg ataatgatga gtagtaatat aactattgaa atggttgatt
    20641 cagtctttga aagagttcca ggagcaactt atgcagaagc aaaagaagca ttagtaatgt
    20701 gcaatggaga tgtaattgag gcagtaatat atttagaaaa taaaaaaaat acttgtaatt
    20761 gtaaagcaaa atctgctaaa gaaactatgg aagaagtatt tggcaaagat ggagaaaata
    20821 taaagtttca attaaaagag cttcttagaa aaagtagtgt agtgagaata atagttgaaa
    20881 aagatggaaa aactatgatg aacattcctt taacagttgg agttgttgga ttagcttttg
    20941 taccattagc tactttagtt ggattatcag ctgctgttat aagtaaatat cgtataaaag
    21001 ttcaaaatga agaagatgga gaaattgtag atttaggtga attgaatgaa gaaaaacttc
    21061 acgttttgaa gaatatgata actaatgcag caaaagatgt gaaggatgta gtagttgaca
    21121 aaaaagaaga tgacaaagat gtaactgctg accttatgaa agaagaatct gaaaagaata
    21181 aagaagacga agacgaaaat aaatagatat aaagtgactt ttaaaaaatg aagagaagat
    21241 aattataaga attatcacta acattgacaa attttataga atttgatatt ctaaaagttg
    21301 tagaagaact attaaaatag cctttcgtgt agacgagagg ctttattgtt ataggaggga
    21361 tttttatgaa ttttcaagag atgatactgg cgttgcaaaa atactggtca aagcaaggtt
    21421 gtatcatgat gcaaccttat gatattgaaa aaggtgcagg aactatgaat cctaatactt
    21481 ttttaagatc attaggacct gagccttggc aagtatgcta tgtagagcct tcaagaagac
    21541 cagcagatgg aagatatggt gaaaacccaa acagactata tcaacatcat caattccaag
    21601 ttatactaaa accttctcca gataatatac aagaattata tttggaaagt ttaaaagaga
    21661 ttggaattga cccaagtgag catgacataa gatttgttga agataactgg gaagctgcta
    21721 cagttggtgc ttggggactt ggatgggaag tttggctaga tggtatggaa ataactcaat
    21781 ttacgtattt tcaacaagta ggtaatattg aatgtgagct tgagacagga gaaattacat
    21841 atggattaga aagattagct atgtacattc aagaagttga tagtgtttat gatttaaaat
    21901 ggaatgataa aataacttat ggtgaagtat ttaataaagc tgagtatgaa aactcaatgt
    21961 acgcatttga attatgtgat gcagatatgt tgtttaatct gtttgatata tatgaaaaag
    22021 aagcattaag acttatggaa aatggccttg taataccttc atatgactat gtgttaaaat
    22081 gctctcatgc atttaataca ttggacgcaa gaggtgcaat aggagttagt caaagagctt
    22141 catttatagg tagagttaga aatatggcaa agactgttgc agaaactttt gtaaaacaaa
    22201 gagaagaaat gggattccct cttttaaagg acggtgacaa ataatgaaaa attatctttt
    22261 atttgaaatc ggtgttgaag aaatgccatc aagatttgta ggcagtacac tagaacaatt
    22321 aaaaaacaat cttagtaaat tatttgatga aaatagaata gcttttgata aaataaatgc
    22381 gtatgggaca ccaagaagac ttactttagt agtcgaagga ttgagtgata gacaaagtga
    22441 tttagaagag gaaataaagg gtcctgctaa gaaaattgct gttgatgcag aaaataattt
    22501 aacaaaacca gcattaggat ttataaaaag caaaggatta agcgaatctg acatatattt
    22561 taaacaagtt ggaaaagaag aatatatatt tgcgactata aagcaagatg gaaaagaaac
    22621 ttcagaagta ctaaaagaca tattaccaga gactataaaa tctgtagtat tcccaaaagc
    22681 tatgcgttgg ggaggaaaaa atcttaaatt tgcaagacct ataagatgga tagttgcatt
    22741 gttaaatgat aaagtattag agtttgattt agaaggaata atatcttcta atgtaacaaa
    22801 aggtcataga tttttaggtg aaagtacaat agaagttgat tctatagaag attattttga
    22861 aaaattagaa aaaaattata tagttttaga ccaaaacaag agaaaagaaa tgataagaaa
    22921 acaatgtata gaagtagcaa attctttagg tggagaagtt gaatttgatg aagatttact
    22981 tgaagaggta acttatttag ttgaatatcc aactgctttt tatggagaat ttgatgtgga
    23041 ttatataaaa ctaccaaaag aagttgttat aactcctatg aaacaacatc aaagatattt
    23101 tccagtactt aaagaaggaa aactgttacc taactttata gctgttagaa atggtgattc
    23161 ttacagaata gacaatgtta aagctggaaa tgaaaaagtt ttagaagcaa gacttgcaga
    23221 tgctttattt ttctatagag aagatactaa gagaaactta gaaagctaca tagaaaaatt
    23281 aaaaactgtt gtattccaag taaaactagg aactatttac gacaaaactt taagacttga
    23341 aaaattaagt gctgatatac ttgatagttt aggtttagta gatgaaaagg cagatactat
    23401 aagggctgct aaattatcta aggcagattt agttactgga atggtaggag aatttgatga
    23461 attacaaggt tttatgggaa aagaatacgc aaaagttgga ggagagaatg atgttgtaag
    23521 tgaagctatt tttgaacatt atcttccaag atttgcagga gatatacttc ctaagactaa
    23581 tgcaggggtt gccttatcaa tagctgataa gttggattca atagcaggtt tctttgctat
    23641 aggaatacaa ccaacaggtt ctcaagaccc atatgcttta agaagacaag ctttaggtat
    23701 acttagtata cttatggaca gaaaagttgc tgtggatata aaagtactta ttgaacatgc
    23761 tttagataat tattctgaat tagattttaa taaagaagaa gttgttgagc aaataatgaa
    23821 tttcttcaat gagagagtaa aaaatctatt taaagattta ggaataagat atgatgttgt
    23881 tgatgctgtt ttaagttctg atataaatga tgtttctgat atgcatatga gagctttaga
    23941 gcttaataat tggctagaaa aagatgaatt agtggagatg cttactgcat ttaatagagt
    24001 ttctactcta gctcaaaaag cagaaagtga taaaattgat gaatctttat taaaagaaga
    24061 tgctgaaatt agactttaca atgaatttaa acaagtaaag gtaaaagtta atgaattatt
    24121 aaaggataag aaatatggta ttgctttaga tgaatttgca tctttaagac cagtagttga
    24181 taatttattt gatacagtta tggttatgga taatgatgaa gctattaaga acaatagact
    24241 tgctttactt aaacaagtat atgatactat gctagaaatt tgtgatttat ctaaaattgt
    24301 ttataaataa aatttaaact atttataaga aataaggctg tctcaaaata gagatagtct
    24361 tatttttcat tgttgagatg atgaaaatat atttgatttc atagaaaaag agtgtctcat
    24421 aaactaaaaa gttcattttg agacacccat gctttttgta agtaaatata ataaattata
    24481 ttttatactt atcagttatt ttgtttaaaa tattatcatt tgaatttacc cattcataaa
    24541 aattgcctga tgatgcgtcc gatattttat aaagcatttc aggaatatca ctagctttaa
    24601 aatctccaag tgattttccc aatctagtct tacctatttc aaaactgcct ccaacaaata
    24661 attcaaatgc atctgtagat ataccatcaa cattcttctt tttaccacat aaacctatgc
    24721 taccaacttg atgaacacca catgaattta aacatcctga tatatataac ttaggtgctt
    24781 tatttaaaat ttcttcatta ttttgtaatc taaaataatc tatgatttca tgtaacattt
    24841 tctgactatt ttgtatgccc atttgacaaa ttggaacacc tatgcaagat atactttgtt
    24901 ctaattgaga attacaacta atagttttac ttatttctaa tattcttttt gcttcatttc
    24961 catttaaatt taaaatatat aatccctctg tcattcctag tctaatcata ggattttcaa
    25021 cattatctaa ttctttaagt aaagtactta aatcctttgt taacaaaata cctccaactg
    25081 gatgtatata tacagtgtat aaaccatcct gtttttgagg tattagtcta gaatcttgta
    25141 tatctatttt aactccaggt ttagagtaat ctatttcttc aatattgagt tcaagactac
    25201 cattttcttt ttctaattta tagtattctt taaatttttc taagaatagt tcttcaccaa
    25261 gtgattcgac catatatcta accctagctc tgtttttatt ttcataattt ccataatcca
    25321 taaagaattt aatcatacct tcaacacaat ataaggcgtc tttcggcttt ataagttcat
    25381 caagttctaa agcaactttg ggttgtttac ctagacctcc acctaagaaa actctgaaat
    25441 atggttcatc atttttcaaa gtagcaacaa atcctaagtc ttgtatacta caatgagcag
    25501 tatctgtgta acaattagaa taagaaactt ttaattttct aggtaaatgg tatgtagtag
    25561 catttttgat aaaatattta tcagtagcaa ctgcatatgg agtaacatca aagacttcac
    25621 tagggtcaac tccagataat ggagataatc cgacatttct aggataatta ccaccaccac
    25681 ctctagtgaa tatatcattt tttattcctt cttccatgat atcaacaatt gaatttatag
    25741 ataaatcgtg taattgtata gcttgtctag ttgttaagtg tatcttatct aagttgtgtt
    25801 taatagctat ttcatagatt ttattaagtt gatactgaga taaaactcca gcagatactc
    25861 taagtcttat cataaaagat tttttgtctc tttgagcata aacaccatat ccaccagaaa
    25921 atcccttata ttgcatttta tttatttctc catttaaaaa ttttgaagaa tattctttaa
    25981 aattaggtag ttcatttaac aatatctttt taaaattatc cattatttca cctcattgtt
    26041 agtcttgtat aaaaatatat ctattgtata atagatatat atattattat ctagtcagga
    26101 taaaaatata acagaataat tctattaaaa gtaagaataa taaggacata gtgagtattt
    26161 tgtttttatt ttacaaatta agtataatat ttttgtttta taaaatataa ttaagataaa
    26221 tagataattt tgtaatttta atatataata tttagtagag tgtgggagta gcacttaata
    26281 tttgcaggag gagtttttgt atatgggaga aataataaat gcattagata gagccctaga
    26341 cataattttg ctgttatatc atgaaaagag agaaatggga ataactgaaa taagtaaggc
    26401 tatgggagta tataaaagta ctgtacatag aactttggtt actcttgaaa acaaaggttt
    26461 tgttatacaa aatgcagaga atggtaagta ttggctagga ataaatttat atgcaatagg
    26521 tatggttgtg ggagaaaaaa tgtcattgac tgaaatagta aaaccatata cgaaaaaatt
    26581 aaatcaagaa tttaacgaag tagttaatgt atctatatta gaagaaagag ctcaagattc
    26641 tccaagaagt atcataatac ataaagagta tggttcaaat caattacttt cagtaaatcc
    26701 atccgttggt tcaagtagtg aatgttattg ttcagcagtt ggtaaatgtc ttatggcatt
    26761 taatgattct atagattttg aaaaatatag aaaaacacca atacacaagt atacagaaca
    26821 tacaattgat aattgggatg atatgatgct ttttttagca aaaataaaag aacaaggata
    26881 tgctatagat gatgaagaac tagaacatgg actaacttgt attggagcac ctatcttaga
    26941 taaaaataat aaagctattg cagccataag tttgtcaggt ccaactataa gaatgagaga
    27001 aggggacttt gagtataaga ttaaaagagt tatagaaact gcaaaaagta tatctgaact
    27061 ttttagatga tttttaatct cgataataaa aataggctat atttaaattg ttatttgtaa
    27121 atatcagttt aaatgtagcc tatttttctt taatctaaaa ttaaatattc ttaaaattta
    27181 aaatgttatt gaaatatata agcgaatgtg ttatctttta attaagcaat aaaaatagaa
    27241 caaggttcta tactatagaa caaaattgat gcatatatag tatttataca aaatataaat
    27301 attatatatt taaaattaag taaaaatatt acataaaggg gagatttgag aaatggaaaa
    27361 agtcaagttg agtgttgaaa gatgtaaggg atgctatctt tgtattgaag cttgcaaaaa
    27421 agatgcaata agtctttctg actacacaaa taaaaaaggc tttgtaacta ttaaagtcga
    27481 tgaagaaaaa tgtattcaat gtggcgcttg ttatacaatg tgccctgatt tagtatttga
    27541 gatattataa attattttta ttagagggga gaaaaggtat gcaaagttta ttaattaaag
    27601 gaaatgaagc tttagcagaa ggtgctatac gtggtggctg cagattttat gcaggttatc
    27661 caataacacc acaatcagaa atattagaaa tgatggcatg gagacaaaaa gaagttggag
    27721 gagtatttat ccaaggtgaa tcagaaatag ccagtgtaaa tatggttatg ggagcaagtg
    27781 cacttggagc aagagctatg acttcttcat ctggtccagg attttcatta aaacaagaag
    27841 gtattgcata ttgggtatca gctggtttgc cagcagttgt agcatgtgtg caaagatatg
    27901 gtataggtga tggatttata ggagctggtc aagataatta ttggcaagca gtaaaaggcg
    27961 gtggaaatgg agattatcat ttaatcgtgt tagcgcctaa cagtgttcaa gaaaatatgg
    28021 atatggcata tgaatctttt gaattggctg aaaaatatat gcatccagta cttatacttt
    28081 ctgatgctac aataggtcaa atggtagaac cttgtatagc accaccaatg aaagaatacg
    28141 atatggataa agctccatgg gctgcaaaag gaacacctgt aggagaaaaa aataaagtaa
    28201 taactgatat aacatatttt gaagaccaag atacatggca aaaagggtat atagaaaaaa
    28261 tgagaaaagt tcaagaagat gaacaaagat gggaagagat agaaatagaa gatgctgaag
    28321 tggtatttgt ggcatacggt atttcatcaa gaatagcaga aggtgcagtt agagatgcta
    28381 gagcaaaagg aatgaaatta ggtctaataa gaccaaaaac attgtggcct tacccaagaa
    28441 aagcatttaa gaaattaagt gattcattga agggacttgt aacagttgaa atgaacatga
    28501 tggcacagat gaaggaagat gtaattatag catgtgataa tagatttcca gtatattcag
    28561 tagcaacagc tcaatatatg gcagaagtaa atcaattaat agattttgct caacagatta
    28621 tagatggaaa agctaagcaa gaggaggtat tttaattatg gctaagaaag caccagcaat
    28681 aatgatgtgt gaaaatatgt tttgtggagg ctgtggacac tctatagtcg atagaattat
    28741 tggagaagta ttaacagaaa tggatatatg tcaagataca attatatgtt cagatatagg
    28801 ttgtaatcat atgtttcaat ttagtatgaa tgtagatgtt gtcgttccac ctcatggtaa
    28861 aatgggtgca gcaatggcag ctatgaaaag agttagacca gataaatata tatttacaat
    28921 agctggagat ggtggagctt atgcgatagg gcttggggaa actatgtcag ctgctactag
    28981 aaatgataat gttatattcc ttgttatgaa caataatatg tttgcaatga caggagggca
    29041 aatggctcca actactatag aaggtcaata tacagcttct actccagcgg gtagaaatta
    29101 cgcagatcat ggttcaacat ttgatgttgt aaaagttatg ggaaatttag atatagcata
    29161 tctagcaaga ggaacaataa ctaaccctaa agaaataaat acaacaaaaa gatacatcaa
    29221 aaaagctcta gaaaaacaaa aagaaaagaa aggtttttgc ttaatagaag tgcttgtacc
    29281 atgtccaaca aactggggat taaagccagt agatgctatg aagagaattg aaaatgaact
    29341 tgttccaaag tatccacttg gagaatttat tgattaggga ggaaataata tgttgaatga
    29401 aattatatgt gctggttttg gaggacaggg agttcttaca gcaggaaaaa ttataatgta
    29461 tgttgcatat aaggcagaaa agaaaattac atggttccca tcttatggaa atgagatgag
    29521 gggaggaagt gcaaattgca atgttgttgt aagtgatgaa aaaattgcaa atccttgtgt
    29581 aaaaaatcca gatatactat tgggaatgaa cagcgtatca gtagataagt atgaaagttt
    29641 aatgaaaaaa aatggttata tgtttgtcaa tgaatcacta gtaagtaagg atagaaagta
    29701 cagagaagac attaatgtta taaaagtacc tgttactgaa atagcacaaa atttaggcaa
    29761 tgaaaaagct gctaacattt gcatgttagg tgctatggta aagagtttgg atttatttac
    29821 aaaagaagaa tttgaaagtg gtatgtgtga atactttgaa aatcaaggca aaggtaaatt
    29881 caattctaaa aatgtagaag catttgaagc aggatacgac tacgaatgaa tattttaaat
    29941 atttaaaata attattgaaa tacttatttt tatatgttag tatttaatta ataaaatata
    30001 gaacgtcgtt ctggacaata ggacgaagtc tttaggccgg aatacaagaa cgacgttctg
    30061 tatagtagaa ctagggggtg ttaaattgaa agttttagta ataaatcctg gtggtacatc
    30121 cacaaaaatt tctgttttcc aagatgaaaa tgaaattttg aaaaaaaata taacccatac
    30181 aagagaagat ttaaaaaatt tttctaaagt atttgatgaa tatgattata gaaaacaact
    30241 gatagtagat attttaagta gtgagaatca tagtataaat tcttttgacg cagtagttgg
    30301 tcgtggtgga cttatgaagg ctataaaagg tggtacctat actgtgagtg aagaaatgat
    30361 tgaggatatg agaaatgaaa taaatgggga acatgcatca aatttaggtg cattattagc
    30421 taaaactata gctgatgaaa taggagtaca atcatttgta gtagacccag tttctgtaga
    30481 tgaatttgat gatgtatcga ggattacagg aatatcagac atagaaaaag caagttggtt
    30541 acatgcatta aaccataaag ctgtttcaag aaaaattgca caaaaactag ggggaaaata
    30601 cgaggattat aactttattg tagctcattt aggttcagga atatcgattg tagcacataa
    30661 acaaggcaaa atgattgatg gaagtggtgg taggtctgat ggtccatttt ctccagaaag
    30721 gagtggtgga ttacttgcat atcctcttat agaattgtgt tactccggaa aatatactca
    30781 tgatgaaatg gtcgcaaaag taagttcgat tgggggaatg tacgattatt taggaacaaa
    30841 ggacatgata gaaattgaaa acagaatcaa ggagggtgat gaaaaggcaa aacttataat
    30901 ggatgcattt atttatcaag tagcaaaaga aatttctatg tatggagctt cactttcagg
    30961 gaatgtagat agagttatct tgacaggagg gatatctcac tcagaaatgg tagtcaaagg
    31021 agtagcagaa aaagtttcat atctagctcc aatagagata gtaccaggag agatggaaat
    31081 ggaggcactt gctctaggag cacttagagt acttaatgga gaagaaatag caaaaactta
    31141 ttaatattta ggagaaagag tatgttaaaa gattttaata atttattaga agaggctaaa
    31201 aagcttgaac ctgttattgt aagtgttgct gttgcagaag acaaagaagt attaaaggct
    31261 gtgaaatcag caacagattt aaacattata aagccaattc ttgtaggaga caaggataaa
    31321 atagaaagta tatcaagaga aattggatta aaaggtcatg aaataatagg ttgtcaaaat
    31381 cccgatgaat cagttaaaaa agctgtagag atagttaaaa ataaggaagc taaagttctt
    31441 atgaagggat tagtaaatac aagtgtctat atgagagcta tattaaataa agaaacgggt
    31501 cttagaacag gaagattatt aagtttgctt gcagtatatg aattacctca atatcataaa
    31561 cttctttatt gtactgatag tggaataaat gtatcgccaa acttaaatca aaaaaaagat
    31621 ataatgacaa atgcacttct tactatgaaa agtataggca tggaaaatcc taaaactgcg
    31681 atacttactg caaatgaaat ggtagaccct aagatacaat ctacagtgga tgccaaccta
    31741 cttgtagaga tggaaaaatc gggagaaata ccaaagtgta tagtggaagg tccaatagca
    31801 tttgatgtag catttgatgc acatgcagca gaacataaag gtattaaaag taatattgct
    31861 ggtgatgttg atttattagt atttccaaat atagaagcag ggaatatatt aggaaagtca
    31921 tggcttagat ttaataaagc taagtgggca ggtatagttt taggagcaac aaatccgata
    31981 attttaggtt cacgttctga cacagctgaa ataaaaataa attcaatagc attagcgtgc
    32041 ctagcatcac aataagaaat tattattaag gaggagaaag tattatgaaa tatgcaaaaa
    32101 gaatggatat ggtaaaagct tcagctataa gagcttctca aaagaaaata gctcagaagg
    32161 tggcaagtgg tggaactgtt atatcttttg ctgcagggct tcctgaccca aatttatttc
    32221 caatagaaga gataagtgaa ataactcaaa aagtacttaa tgaaagggga aaatttgccc
    32281 tagcatatgg acctactaaa ggtgaagatg agttgttaga tctattagta aaaagaatga
    32341 aagaagaaga aaatattgat acaaaagcag aaaatattat aataactact gggtcacaac
    32401 aagggatagc attaagtgct atgattttac tagaaaaagg agatatagta gttacagaaa
    32461 atccaagtta cttaggtgca ataaatgcat ttagacctta tgaatgtgat tttttaggag
    32521 tagatactga tgatgaagga atggtaacag atgatttaga taaattatta tctgaaaatt
    32581 ctaacataaa ggtaatctat gtaataccaa catttcaaaa tcctacagga aaaacatggt
    32641 ctttacaaag aagaaaagat tttatggaag tcgtgaataa gtatgatgtc atagtaatag
    32701 aagataatcc ttatggagaa ataagattta caccagagcc tctacctaca cttaaatctc
    32761 ttgatactaa agataaagta ttatacttag gttcattttc aaaagtatta tgtccagggt
    32821 ttagagttgc ttggatgtgt ggtaatgtag acatcataga taaggcagaa cttttaaaac
    32881 aaggtataga tttacagtca aatcaatttt cgcaagtaca agtaatagaa tttttaaaga
    32941 aatacaactt aaatgaacat atagaaaaaa taagagcaga gtataagaaa agatgtctgc
    33001 taatgttaga tgctatgaag aaacatttcc cagaggaagc taaatataca gaaccagatg
    33061 gaggaatgtt tatatgggtt gaacttcctg aaagtataaa tgtagatgat ttattggata
    33121 aagccattga tgctggagtt gcttatgttt ctggagagtc cttctttgca aataatggtc
    33181 caaaaaatac tatgagactt aactatacaa caatgtcaga agaacaaatc gttaaaggtg
    33241 ttgagatact tgcagaagtt ataaaaaaag aactcaatta tgcttgtgaa taaatataaa
    33301 aagtgagggt ttaaatatgg gagaaaaaga aaacggtata aagtttggaa agttaatgtt
    33361 tcaacttgtt attatagcaa tatcttggga attagtttat attataccat ttatccaata
    33421 tacattatat gatccaatcc taaaagcatt agaatgtaca aacactcaac taggttttct
    33481 acttacaatt tatgggttag gtaatatatt tggagctcct ataggaggct ggttagcaga
    33541 tagatttgat tatagaaaga taattttagg ttctgtattt cttaatggag tagtatcatt
    33601 tttatttgca tttaatatga actatccatt tgcagttgct acttgggtag gttgtgcaat
    33661 cacatcatta gttatgaact atccttctat ggtaaaaata cttagagtta taggaaaaga
    33721 taatcaaggt aaagtttatg gattcaatga agctatggtt ggagtttctg gcgtagtaat
    33781 gggagcaata ttcttatata tttatacatg cttttcaact cctgtattgg gtatgagatg
    33841 ggtaatgata tctttaggaa tattatcaat agtgatgtgt ccagtattat ggtttgtaat
    33901 taaagatgta gatatcagag aagacaaaga agaagaagca agtgaaaaaa tgtctgctgg
    33961 cgattttatg acagtactaa aatcaccaaa cacttggcta gtaggaataa gcatattctg
    34021 tgtatattca ttcacagtta caatgtctta ttttacacca tatataacat cagtacttgg
    34081 aggttctgtg gcattgtctg gggcattagc aataataaga caacatggtc taaaattgtt
    34141 tggagcacca tttggaggat attgtgcaga taaagtaaaa tcacctacaa aagtactact
    34201 accaatatat gtatttggta tagcagtaat aattttattc ctagtactac ctgcatctac
    34261 tccaatgact atctttatag ctttaacatt tgtagtaggt atattaggtt acatgggaaa
    34321 aggtatatac tatgcagttc aagatgaagt aaaagttcca gttaaatatt cagcaactac
    34381 tataggtata gctgcagctt taggattttc accagatgta ttccaatttg cattaatagg
    34441 acactggata gatacttatg gcaataaagg ttacacatat acatttatat tccagatagc
    34501 aattctaata attggtatac tatcttgttt atatatatta aaagttaaga agaaaagaga
    34561 aagtaagtta gaagcataaa tattgtaaaa ataccaaatt attaagtttt atagcaatac
    34621 ttaaaattta aagtgcaaca caccaaaatg ttatcaagtt ttctaggttt tagtataaag
    34681 ttacccctaa aggtctggaa ttgagtagca attatcatct atttatatat ttacataaac
    34741 ctatttaatt taaattaaaa gaatttcaaa aataggtggt aattgtactc aattttacac
    34801 ctcataataa atacgaaaat ttaaaatcta actatatact attcaattat atattaataa
    34861 ttgtatatgg tactatttat atagtaacag tttcaggctt ttcattacat gtattccaat
    34921 ttatattgtt tgattatttg tcaaatacat atcgttaaaa agtttataaa tttacgttta
    34981 tatatcgatt aatattcttt gttttagaga tagatactta tagcttgtgg attaaaaata
    35041 atataaatag aagatagatt ttttagatat attgagttga agattatata gaatgttgaa
    35101 acatagctat ttaaattatt gtctataaat ataaaatgaa tggtggtgag ttaagtgacc
    35161 gatttagtta acaccattaa tggaattgtt tggtcacctg tattagttgc aatgtgtttg
    35221 tgtataggat tatatttttc aatgaaatta agattttttc aaataaaaga tgtaaaagaa
    35281 atgtttactc ttttgcttga aggagatagc tctcatgttg gaatatcttc gttccaaggt
    35341 tttgctacat ctatggcagg aaggatagga actggaaata tagctggtgt agctgtagcg
    35401 atagcaatgg gagggccagg agcattagtg tggatgtgca taatggctac attagggtcg
    35461 gcaactgcat ttgtagaatc tactttagct cagatatata aagatgagca tgatggacag
    35521 tacaggggag gtcctccata ttactttgaa aaaggtcttg gttggaaaaa atgttcaatt
    35581 ttattttcag tggttgcaat cataagttat acatttttta tgcctggcac acaatcaaat
    35641 actctatatc tagcaatgaa tcaagcattt ggattttcaa aaatgacaat agcagttaca
    35701 tcttctattg cactaggtat aataattttt ggaggaatta aaagaattgg tttatttgct
    35761 gagaaagtag tacctataat gggtggagca taccttatta tgacattggt aataatcata
    35821 gcaaatataa atctagttcc aggagctatt atgacaatgt ttaaatctgc atttggattt
    35881 ggttcggttt ttggagggat gttaggttca gcaatatctt ggggagtaaa aagaggtata
    35941 tactcaaatg aagcgggaga aggttctgga acttatggtg cagcagcagc agaagtgagt
    36001 cacccagcca aacaaggatt agtccaagct ttttctgttt atgtagacac actattaata
    36061 tgtatggcta caggtattat gattataata acaggaatgt ataatgttac agatgtttac
    36121 acaacattac caggtgtaga accaggtcca caatatgtac agagtgcaat aaatacatta
    36181 catcctcaat taggtgatat ttttatagca atagttttac tactatttac atttacaaca
    36241 ttattagcct tctcatacat gatggagacc aacgtatctt acttagtgac tagaattaag
    36301 gcagaaaaac atgaaaagca cataattaat gtctgtagat ttatgcttat aatatgtgca
    36361 gcaatgtgtt gctttataga accacttaca agttgggcac ttggtgatat atgtataggt
    36421 gtattaacat atataaactt agttggtata tttacactaa aaaaaccagc tataaaagca
    36481 tattacgatt atcaaaggca gaaaaagatg ggagtaaaaa ggagcgatag aacttttaat
    36541 cctatagaat tagatataag aaatgctgag ttttgggaaa atagatactt aaaagaggat
    36601 aagcatgagt taaattaaag ttataataaa atataaaaat tactaaataa atttagtggg
    36661 aggtaagatt ggtatgaaag aaagaataat acaagtggct gattcaaaga aagaaaaaat
    36721 tctagggcta tgtcaatctt tatatgatga accagaaatt gctttgcaag aatataaatc
    36781 tgctaaaaaa atatcagaat ttctaagaga agagggtttt gatgttgagg aaaacttggc
    36841 aggtatggct acagctttta aagcaaccaa gaaaaatgga gatggtccta aaatagcatt
    36901 tatagcagaa tatgatgctc ttccaggcaa tggacatgca tgtggacatc atttaattgc
    36961 atctatggga gttggagctg gaatagctct ttcaagtata ctggatactt acaagggaga
    37021 agtaagtata attggaacac ctgctgaaga aactggagat ggaaagcctt acttgataga
    37081 acatggtgta tttgatggct atgatgcagc aatgatgata catccaaatt caaaaacttg
    37141 tgtaacacct gaaattatag caataggagg tctagatttc atatttactg gaaaagcatc
    37201 tcatgcagga gctaagccat ataacggaat aaatgcttta gatgcagtag tactactata
    37261 taataatata aatgcactaa gacaacaatt agtagatgga acgagaatac atggtattat
    37321 actagaagca ggaactgctg caaatgtaat acctgatatg ggaaaagtaa gattagagat
    37381 aagggcaaaa gaacaaaatt actttgatga agtagtagaa aaagtgaaaa attgtgctag
    37441 aggtgctgca atagccactg gatgtgaact tgaattttat cactttgaac caacttgcca
    37501 aggattaaat gaaaataaag ttttggtaga catatttaca aagattatgg aggaatttgg
    37561 aatatatgaa gatgaacaag taatgttagg ttcaacagat atgggaaatt taagtcaaat
    37621 aatgccatgt atacatcctt tgatgaagtt ttctgaaaat ggagaagaac tacatacaaa
    37681 agaatttttg gaggcttcta taaattcata tgcaaaagat agagtaattg atggtataaa
    37741 aatattagct ttaacaggat ttaatttatt tgaaaatcca gagttattga aaaaaatgaa
    37801 ggaagagtag aacttagact atttttaatt atactcttta aaataagaag agtgtctcaa
    37861 aatgaacttt ttagtttatg agacactctt ttttgcatga aattaaatat atttttatta
    37921 ttttaacaat gaaaaagagg cttatctgtt tttatataac cttttttaac ttgtagcaca
    37981 aaatatcatg aatgattaca attcgaatga taaaatcgat tataagatat ataggagggg
    38041 tacatatgga aactttagaa gtaagaaata ttgaattgag tggtacaaat tatgagatag
    38101 gatacagact aggagaattg gttgctaata tgccagagat aatagaaggt cagattaata
    38161 aatctaatct ggtaagcaaa aaagaagaaa aagagatgat agagttgttt gataaatatt
    38221 gtccaggtct taatgaagaa ttgcaaggtt ttgctgatgc aattcaagtg aattgtaatc
    38281 aaattttata ttatactatg acttatctta aaccaggttg tagtcaagtt gcattaacac
    38341 cagaattaac tgaaaatggg catgtactat ttgcacgtaa tttcgatttc tcacacaata
    38401 tggaggattt tgttttatgt aaaactaaag taaatggaaa atatgcacat ataggtacta
    38461 ccgttatgca atttggaaga ggtgaaggta tgaatgaatg tggattaggt gtaagtcagt
    38521 catcatgtgg tattcctgta ggcaattcag atggtttgag aaaaccagca attgtaggtt
    38581 tacagttttg ggctgttatt agatatttgt tagaaaattg caaagatgta gatgaagcat
    38641 tagaatattt aaaagatatg ccaattgcat acaatattaa tttattgctt gcagataagt
    38701 ctggaaacat tgcacttgtg gagactttag atgggaaaaa agaagtaaat ataatcaaca
    38761 gtttagaaag taagagagaa tattttttac actctactaa tcatacacat attgataaac
    38821 ttcataaatt agaaccacaa tcaatgaaaa attctattca tagatataaa ttaattaaag
    38881 aatatataaa taaggctaaa aaaattggag agaaagagtt aatgaattta ttgtctttaa
    38941 agtatccaaa tggcttatct tgtaattact ataatgattt ttttggaact ttaaaaagta
    39001 tagttatgga tttaaatata ggaaagttta atattttatg gggtggacta gagaataaat
    39061 gggagagcta ctatttaaaa aatgacatta aatctataac acagaggata aacataaata
    39121 ttgaaaaagc accatctgac ttttttgatt tcattgaata aaaaatgtat ttaattattc
    39181 taaataatta ggctatataa atcaactaaa agtttttatt tatcgtattg aattagttat
    39241 aatattttag tatagtaaaa aatagtgcta ttttacatat ttaaagagtt taagtagaag
    39301 agaggtgcca tattggatta cttaaagtat tttgaaaaag ctgtaatgta tattgagaat
    39361 aatttacatg aaaatataac tgtaaatgat gtggcaaaag aaactggata ttcttattat
    39421 catttaacac gcttatttaa gtctatgttt ggtgagagtg taggaagtta tataaaaaaa
    39481 agacgattag taagtagtac aaaagaactt ttatatagtg ataaaaaagt gatagatata
    39541 gctattggta gtggatttga atcttcggaa gcatttagca gagcatttaa atctatatac
    39601 aaggttagcc ctatagaata tagaaaaaat agaattgatg tatttgttgg taaaaagaaa
    39661 aaattagagt tagattttat gagacatctt gttggaaata taacgattaa accagttata
    39721 aaagaaatag aaaaaataaa ggtaataggt ataaaggata aagtaatttt agaaaataat
    39781 tcattacctg acttgtggga gaaattcaga aaagtacatc atattgtccc aaatactttg
    39841 ccatcaaaga gagtttttgg aatctgtgaa gcaatctctg aaatacacct agttagtgaa
    39901 agtatggaat ttaatgagat aataggactt gaagttaata gttatgatgt gattccaaat
    39961 tcatttgttt caaaaactat taaggaagga aagtatgcta tatttactca tactggtagc
    40021 ttagataact tagacaaaac ttatgaatat atatggggta cttggttttt aagttcaaaa
    40081 gaagaactgg atataagaga tgattttgaa gtatatgatg aacgattttt aggtcctagt
    40141 aatgtgaact cacaaattga tatttatata cctataaaat aatctataag aaaactaaaa
    40201 gataatttga ttaagaaata gatgttcgta aaagagcatc tattttttat ttttatcaga
    40261 tttagataat tttaataata aaagaaataa aaatatatta taaaaacaat ttgattggaa
    40321 ttttcagaaa attaatgcta taattaaaag taaatttaaa gggaggttat aaaatggcta
    40381 aattaactct agaacatata aaaggaaata catattatat tccactccct acaatagtag
    40441 gtgtatacgt agatggtaaa gatgcaattt taattgacag tggaaataat aaggatacag
    40501 ctagacaagt tttaagatta ttagaagaac ataatttaag tcctaaatta ataataaaca
    40561 ctcattcaaa tgcagaccat ataggaggaa atgcatattt gaagaatcaa acaaaatgca
    40621 agattgctac gactaaaatt gaaggatatt ttacagaaaa tccaatatta gaatcagcat
    40681 ttttatatgg tggctatcca agtaaagcac tgaagaataa atttttatta gcaaaggaaa
    40741 gtgaagttga ttatattata ccttcaaatg gcaaaattgt agatacagaa cttgaagcga
    40801 tttctcttcc aggtcattat tttgaaatga ttggtgttag aactccagat aatgttttgt
    40861 ttgttgcaga tagtcttaca ccagagaata taattactaa atatcatttt ttcttcctac
    40921 tggatataga ttcacagttt aagacactag aaaaattgag aatgttagag gctgatttct
    40981 ttgttccaag tcactctgtc aaaactacag atataaaaag tttgattaat attaataaga
    41041 agaagatgga agaaataata gataatatta aaaaggtttg ttatgagcca gttatgattg
    41101 atgaagttat tgaaaaaatg tgtgatttgt acaatgtcaa gcttgatgct aatcaatatg
    41161 tgttggttgg aagtacaata cgttcttata taacttattt atatgagaat aatatggttg
    41221 aatatatatt tgatggtggt aagatgatga taaaagctgt gtaaatagta ataattttca
    41281 aattatatga tgaaattgtt ttagtatgac tgttatttga aaagtaacat aaaaaaattt
    41341 atataaataa gctaagatga ttgatataaa gttactgata attttaaggt aatatatacg
    41401 ttactataat attatgttat tatttgtaaa taaggggata atttataagc aaattaaaga
    41461 ccttaattta caggaggaat agtgtatatt atgaataaaa aattcaaaaa attcagtaaa
    41521 aaactaagta tattaatttt agttttgact atgtttcttt ttaataattt aactgcaaat
    41581 gcacagatta aagaagattc aataatagga attgatagat atgaaacagc aggacttata
    41641 gcagatagac aaacttatga tactgtaata ttagttaatg gagataaaaa tttatctgat
    41701 gggctttcat caagtggatt agctggagct attaacgcac caatactttt gactaaaaaa
    41761 agtgaaatac caaaagctac tttaaataga ctagataata agagtttaaa tgttgtaaaa
    41821 aaagtatata taattggtgg ttataatact attgaaaatt cagtagaaaa agatataaaa
    41881 agaaaaggta ttcaagtgga aagaataaat ggtaacaata gaattgaaac tagttataat
    41941 gtagctaaaa aaataaatga agtaagtagt gtaaaagagg taatgcttac aaatggattt
    42001 gtaggagagg ctgatgctat gagtatagca cctgtagttg caaaaaataa aggagctata
    42061 atacttacag atgggaaatc agttccattt aagactgaag gtttaaatgt ttacgctata
    42121 ggtggcaaat ctgcgataaa tgaggattta gtaaatgaaa ctaaagcaac tagaatcgga
    42181 ggaaatgata gatttgagac caataaaaag gtaatggaaa agttttataa tggagcgaca
    42241 gatttttata taacaaatgg atatcaatta gtagatgcac taacattatc tcctttagcc
    42301 aaagaaaaac caatcgtttt agttgctgat ggaagtaata aaggtatttt aaaaggagct
    42361 aaaagtataa caaaagttgg aggtattgat gccaatatat ataaacagtg tttagatatg
    42421 attaaatata ataatatgga tgtgactcca aatattttaa aacacttaac ttcagttgaa
    42481 ggaaatgaag tttctgaaat acttatagaa tcagataatt taggtgtggt tgttgaaaag
    42541 acgaatacca ataaatttga gtttgattac gtaagtgtaa ctaatgaaaa aaattgtact
    42601 ttttctgtat ataaagaaaa ttcttctaat aatgtaaaaa atggaaagct agttgtaagt
    42661 gctaagaaaa aaatagataa gaaagatagt gatttgcaag atatgaatgg cgacaatatg
    42721 ataaatgcaa ataaagatag gatggtaaat gtgataaaaa ttggagttcc cgataaaatg
    42781 tattctaatt ttaaagtaga tgttgaaagt ggttcagtag aactttataa tattaaagga
    42841 ggagctactg ttgatgtcaa tgacggaatt gctaacattg ttgataacaa tgtgacaaat
    42901 cctttcaata taaatactaa tagtgggatt tcaggtgtaa cagctgaaac tatatcatct
    42961 gagataaaat ttagagcaaa caatggaatt gtaagtgtaa cagctacaaa tataaatggc
    43021 aatataagtt tatttggaag cgataataaa ggtacctttg atggaatatt taaattaaat
    43081 ctgaaaaaag aaccatcaaa tttacacttg aagttagttg gaaatgggat aaataaattg
    43141 ccagaaggtt ggtctaaaga ttatatttta ggaaatggac aaccaattat tgaagttaaa
    43201 aataatggca taaataatat atcaattgga gaataaaaac atatgaaaat a
//
LOCUS       DAMJWO010000030        42157 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.031, whole genome shotgun sequence.
ACCESSION   DAMJWO010000030 DAMJWO010000000
VERSION     DAMJWO010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42157
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.031"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            34..702
                     /locus_tag="PC366_001622"
     CDS             34..702
                     /locus_tag="PC366_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HDF2577152.1"
                     /translation="MFKIFLFSSEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSKNLGYEFPSLIYFIFIFSKCLIIYADIYMVDVRKFRVNRYALRDNLAI
                     CFIYFSFIFLLNTFTNSQYYYGFLSHSTTAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
     gene            complement(793..2244)
                     /locus_tag="PC366_001623"
     CDS             complement(793..2244)
                     /locus_tag="PC366_001623"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HDF2577153.1"
                     /translation="MNIKYSKEILKSLENAITVVALFEGEDVSTTFDKINMISRNFNS
                     KENSIDTVTLVENNNLVNVCLVGFGKRELLNREKIRIIGGNLCKKLKNILKNEAYKSS
                     DVNVLNLNLNSDEIGSFVEGILLGNYKFDKYKTKSKDFERKEVDTITIFTEKEVECQI
                     EKAKILANSTIIARNLVNEPSNVIYPKTLAIETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIISSMAKKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALTLLGNVATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKAKGATGEPVRTLYYLAEI"
     gene            complement(2260..2700)
                     /locus_tag="PC366_001624"
     CDS             complement(2260..2700)
                     /locus_tag="PC366_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2577154.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDIDNKDKLFTSLEESKNIIEQLF"
     gene            complement(2948..3376)
                     /gene="ytfJ"
                     /locus_tag="PC366_001625"
     CDS             complement(2948..3376)
                     /gene="ytfJ"
                     /locus_tag="PC366_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HDF2577155.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            complement(3330..3959)
                     /locus_tag="PC366_001626"
     CDS             complement(3330..3959)
                     /locus_tag="PC366_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HDF2577156.1"
                     /translation="MELNELFNFKYLIIAVIFIISVTMLILISHINILIIADINNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSIYRLLKKI
                     KIHELYSNINFGTGNIGLTSSVYVLINTLYGNLFNMIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIRPRIKALFNIIIMINKIMNKNKGNKEGDSNESNRFDTKSYGNNS"
     gene            complement(4121..4660)
                     /gene="scpB"
                     /locus_tag="PC366_001627"
     CDS             complement(4121..4660)
                     /gene="scpB"
                     /locus_tag="PC366_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HDF2577157.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIINKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENELIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVATNE"
     gene            complement(4662..5381)
                     /locus_tag="PC366_001628"
     CDS             complement(4662..5381)
                     /locus_tag="PC366_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HDF2577158.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKDKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            complement(5411..6007)
                     /locus_tag="PC366_001629"
     CDS             complement(5411..6007)
                     /locus_tag="PC366_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HDF2577159.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAGYVLIYSMGFAAFNLLPIPPLDGWGVISTFVPYKWNEYLY
                     KFESMSYIILLIALFTGIYQIILSPIYTVLLKIVYLFV"
     gene            6305..7141
                     /locus_tag="PC366_001630"
     CDS             6305..7141
                     /locus_tag="PC366_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2577160.1"
                     /translation="MRQEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPKFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLQ
                     SNLENTNIEIQAVCDYLENNYAEHIVLDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPIDAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            7162..7584
                     /locus_tag="PC366_001631"
     CDS             7162..7584
                     /locus_tag="PC366_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HDF2577161.1"
                     /translation="MENKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFNDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(7795..8958)
                     /locus_tag="PC366_001632"
     CDS             complement(7795..8958)
                     /locus_tag="PC366_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF2577162.1"
                     /translation="MKKLASTALAILIALTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGKIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLN
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNALIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELINTKDINKASYLQMLQRIIDNMI"
     gene            complement(9012..9212)
                     /locus_tag="PC366_001633"
     CDS             complement(9012..9212)
                     /locus_tag="PC366_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protein"
                     /protein_id="HDF2577163.1"
                     /translation="MDDVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            complement(9418..11094)
                     /locus_tag="PC366_001634"
     CDS             complement(9418..11094)
                     /locus_tag="PC366_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HDF2577164.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGVGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDICKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            11311..12048
                     /locus_tag="PC366_001635"
     CDS             11311..12048
                     /locus_tag="PC366_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDF2577165.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTIGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKL"
     gene            complement(12165..12623)
                     /locus_tag="PC366_001636"
     CDS             complement(12165..12623)
                     /locus_tag="PC366_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF2577166.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(12905..13192)
                     /locus_tag="PC366_001637"
     CDS             complement(12905..13192)
                     /locus_tag="PC366_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HDF2577167.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            complement(13270..13695)
                     /gene="ruvX"
                     /locus_tag="PC366_001638"
     CDS             complement(13270..13695)
                     /gene="ruvX"
                     /locus_tag="PC366_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HDF2577168.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKAETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            complement(13901..16072)
                     /locus_tag="PC366_001639"
     CDS             complement(13901..16072)
                     /locus_tag="PC366_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577169.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSYASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGQKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYGTMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILGTFGLE
                     NKEMVGRSYTLVNKEDNVGYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKDNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLLVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAVLLAVSAVVVVFAFAALDILSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIININMIIFEKNN"
     gene            complement(16082..16339)
                     /locus_tag="PC366_001640"
     CDS             complement(16082..16339)
                     /locus_tag="PC366_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HDF2577170.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            complement(16364..19003)
                     /gene="alaS"
                     /locus_tag="PC366_001641"
     CDS             complement(16364..19003)
                     /gene="alaS"
                     /locus_tag="PC366_001641"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HDF2577171.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVRLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAEEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGRISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     misc_binding    complement(19071..19309)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(19452..20531)
                     /gene="mnmA"
                     /locus_tag="PC366_001642"
     CDS             complement(19452..20531)
                     /gene="mnmA"
                     /locus_tag="PC366_001642"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HDF2577172.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDVVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNED
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGEDTIKIVFDEAQRA
                     ITKGQSVVMYDGDIVVGGGIIEKSL"
     gene            complement(20820..21260)
                     /gene="nifU"
                     /locus_tag="PC366_001643"
     CDS             complement(20820..21260)
                     /gene="nifU"
                     /locus_tag="PC366_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HDF2577173.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAQKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            complement(21314..22507)
                     /gene="nifS"
                     /locus_tag="PC366_001644"
     CDS             complement(21314..22507)
                     /gene="nifS"
                     /locus_tag="PC366_001644"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HDF2577174.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGVAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGRVDLRQLEDSIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLENRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            complement(22525..22971)
                     /locus_tag="PC366_001645"
     CDS             complement(22525..22971)
                     /locus_tag="PC366_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDF2577175.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            complement(23080..23850)
                     /locus_tag="PC366_001646"
     CDS             complement(23080..23850)
                     /locus_tag="PC366_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2577176.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADVGEHGEIKAILLKYFEFMMFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDTLAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNAKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRAKGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            complement(23881..25146)
                     /locus_tag="PC366_001647"
     CDS             complement(23881..25146)
                     /locus_tag="PC366_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HDF2577177.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKSFYKINATNSSLEDIKKVISELGSINNVNGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKLDIEKGL
                     KRAVEVLNEDSYMDIECNNNAIEDIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDVIRASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDAHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSIYYIPQENKTEKNIKKYLEYLNSDF"
     gene            complement(25253..26038)
                     /gene="codY"
                     /locus_tag="PC366_001648"
     CDS             complement(25253..26038)
                     /gene="codY"
                     /locus_tag="PC366_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HDF2577178.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            complement(26203..28290)
                     /gene="topA"
                     /locus_tag="PC366_001649"
     CDS             complement(26203..28290)
                     /gene="topA"
                     /locus_tag="PC366_001649"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HDF2577179.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELENEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNTGD
                     KKEKKDTKKVQDAHEAIRPTSVDRTPESIKASLSKDQYKLYNLIWRRFVASQMEDSVF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            complement(28323..29423)
                     /gene="dprA"
                     /locus_tag="PC366_001650"
     CDS             complement(28323..29423)
                     /gene="dprA"
                     /locus_tag="PC366_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HDF2577180.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGYAYLENIKELLYKKAIKYICKYDKEYPENLKNIYNAPKLLF
                     YKGDIGLVNNNFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            complement(29442..31043)
                     /locus_tag="PC366_001651"
     CDS             complement(29442..31043)
                     /locus_tag="PC366_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HDF2577181.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDVSNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQNIKRIFIPIENIKESLLVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVSIMSFLDDKSRKENGELEKDNSYIDCKYTKINNEESKYDEDF
                     KDVKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISIEEMIEVSKV
                     YSILGMINESKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLVAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     KKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFNKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFK"
     gene            complement(31074..31418)
                     /locus_tag="PC366_001652"
     CDS             complement(31074..31418)
                     /locus_tag="PC366_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HDF2577182.1"
                     /translation="MNNKEKGDFGEEIAVNYLLSKGAKILEKNYRLRIGEVDIIANIG
                     DEVVFVEVKSRSNIKYGYPCESVDFKKRKKIIGVAKYYIIKNNLNNTPIRFDIIEVYL
                     LEKRINHIMNAF"
     gene            31603..32763
                     /locus_tag="PC366_001653"
     CDS             31603..32763
                     /locus_tag="PC366_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2577183.1"
                     /translation="MNRKKTFIFIRYLSLFILLISYLNHTENTLYPAITMIILFLIIN
                     NQVRFFSLSSENKFILISYFLELILIFIFCKYIKTFNPLYYVSLILDASFLIKEKYKY
                     ILFSLVIIFSFIIGLDKNLYLALESSSTLLIITLFSVYLENENLSKLYNQSLYDKLRV
                     SKDELKKANADLEIYANSIEELAILKERNRISREIHDSVGHSLSTTIIQLNAIEKLLK
                     DKPLISDLVHELREFVTESFQDVRRAISELKPIEYENYQNLLKIRELVNSFIKLTNIN
                     VRLTISKNTWNLSTNQSIALYRLVQESLSNASRHGKATEIRIFITFNPSNLIITISDN
                     GIGCNNIKRGNGLSSISERIYELNGKVEFDNSNTGFTIRASFPKFSGGDFFE"
     gene            32756..33400
                     /locus_tag="PC366_001654"
     CDS             32756..33400
                     /locus_tag="PC366_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2577184.1"
                     /translation="MNKIKVLIVDDEKLIRKGLNIILSSYDDLEIVGDASNGYEALEF
                     CKTNDVDIVLMDIRMKVCDGVLGTRLIKEYDSSIALLILTTFNDDEYIEDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMYPQKTIEQKHISDMYNLTEKEISI
                     IRLIANGLNNKEISQELFLSEGTIKNNITNILGKLELRDRTQLVIFAFKNKIVI"
     gene            33588..34523
                     /locus_tag="PC366_001655"
     CDS             33588..34523
                     /locus_tag="PC366_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577185.1"
                     /translation="MDIVRVNNITKRFNDKLALDNISFSVKEGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGDIQINGLDLSKDCIKAKSIIGLVPQELALIETLTPFDNLEYFGT
                     YYGLKGKLLQERITEALEVTGLTDVKKKKIKKLSGGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKNISKKQKTTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGD
                     NDYLKSLVSTNTKLIMEIKNINAQLIFDLKNTKGVVSILENNSLLELGVDKKLQLTDV
                     LSVVDKNNSKITRISYEEPSLEDVFLNLTGKNLRD"
     gene            34537..35634
                     /locus_tag="PC366_001656"
     CDS             34537..35634
                     /locus_tag="PC366_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577186.1"
                     /translation="MKLYISVKTMLKVLKSSFMLNLIYFLALPLVLAGFLGMVTESIF
                     QNPIKTDLTSIVIYDKDNTKLSSNLTGYLKNDLSSILTVQKDDSKADLKLTIPKGYEN
                     NLLNEKSNNLSIEKLKSNDNIAILLQDILDTYHEKLYLNNSQKLSSEDFSKLFNKNSI
                     DTSIIKNNVKQNSYEYFALVSLGFFAIIFIMNSILSNYVSESKGLSKRLYSIPVTRVQ
                     FLIYDFIGFWIYSFIFLSLYVLFFRTLGVTFKGNFVILALLCALASYFMTSISTFITT
                     FFSKKYGTVIVYALLFLQTVFGGIFSIVNDVFTKFTSLSPTYLIGTLFSNYETFKTID
                     SIESLIFTCLIASTVLIALSIVKEKYKWREV"
     gene            35637..36701
                     /locus_tag="PC366_001657"
     CDS             35637..36701
                     /locus_tag="PC366_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577187.1"
                     /translation="MIRLTIANIKRYIKNHALLVNMVLFPVILMFYLNFFTGNSENQS
                     MYFSPVAIVSNSSGKYEHKLIDSSKLKENSFGLNEQDKAMDLLKNNKVSAVFILDKNF
                     SSNIDNLKRPEVKCFKTENGGGSLWAESQIESFITNSLKLKIDRNIDDKLTKTNIIDN
                     SSGKNKNSFLIVFLICYFMYINAAHLASDLFSLKKSNTLKRLVSTKHNDIKIIFSIFL
                     GLFFTQAIVYTLTLVCFTSISNFKLTLNTLMIVLANSFVATGFVFWIARVFKNEGSIS
                     LMSTFYSLIGLAISISNMIPSLDKLSFMANLSKLTPFYWTIDAINNNGNILINIIVLI
                     LIGMVFVTAGSLNLRDFARN"
     gene            36942..37439
                     /locus_tag="PC366_001658"
     CDS             36942..37439
                     /locus_tag="PC366_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HDF2577188.1"
                     /translation="MYKIGESVMYPKEGACYISGLVTKDINHHIQKYYELTVIYNSNL
                     KISIPVLNADKIGVRPIMDENEVENFIQSLDKVDCLWVFDRKKRLKLYHDKFHSGDVF
                     EIVKLIKMLMIQDNSKQLCSTDKDFLNKAQRFALSELAAAQCKSYTIVLEEMKNHILN
                     SKNNN"
     gene            complement(37616..37864)
                     /locus_tag="PC366_001659"
     CDS             complement(37616..37864)
                     /locus_tag="PC366_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577189.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELGVLLEEKKELEEE"
     gene            complement(37930..38946)
                     /locus_tag="PC366_001660"
     CDS             complement(37930..38946)
                     /locus_tag="PC366_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF2577190.1"
                     /translation="MEYNELLKSARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCANSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVKQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVYAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            complement(39004..39771)
                     /locus_tag="PC366_001661"
     CDS             complement(39004..39771)
                     /locus_tag="PC366_001661"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HDF2577191.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            complement(39839..42028)
                     /locus_tag="PC366_001662"
     CDS             complement(39839..42028)
                     /locus_tag="PC366_001662"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HDF2577192.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYDISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKRFLFAGRILANRGLQKEGKKV
                     TYSNCYVIESPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEEFIDIKTDLEKVTKANISIRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNFMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKEDKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEEDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
BASE COUNT        13450 a         7328 c         4496 g        16883 t
ORIGIN      
        1 acatattaaa tttattatag gagagaatgt tatatgttta aaatttttct tttttctagt
       61 gaacaatttg taagtctctt tatatttgga ttatttttat actattgtcc aaaactaacc
      121 aaaaatattt taccttatag ctatacagtt gagaagataa tttgtacatt acttgtaata
      181 attatggctc tagagcaatt attacttatt tcttcaggta attatagtac tctaaactct
      241 ttaccaattg gaatcaatta tatctgtata tatctgtgta tagccatact aatttttaag
      301 cagtatcatc tttttaatat atttttttct tggagtttag tttgttcagt tggagaactc
      361 attttttcta aaaacttggg ctatgaattt cctagcttaa tatattttat atttatcttc
      421 tctaagtgct tgataattta tgcagatata tatatggttg atgttagaaa atttagagtt
      481 aacagatatg cacttagaga taacttagct atatgtttta tttatttttc attcatattt
      541 ttactaaaca catttaccaa ctcacaatac tattatggtt ttttaagtca tagcacaact
      601 gctattttta cgtttatttt tgttactagt attatgtaca tacctgctct tttatttaat
      661 agagatactt ttatacttga gaaaaagaaa aagagtaaat aatttactta aataaaaaat
      721 aaagccacat agataatctt aaattacaaa aatatccatg tggctttata aattatattt
      781 tataattgtt ttttagattt ctgccaaata gtataatgtt ctaacaggtt ctcctgtagc
      841 cccctttgct ttgtatccaa ttgattttga tgatgtactt gtccccgcta tatccatatg
      901 tatccaagga gtattcccaa caaattcacc aataaaagct cctgctgtta tacatccagc
      961 atttttacca ccagtgtttt taaggtctgc ttcttctcct tttatcatat ctttaaattc
     1021 atcataaatt ggcatcttcc ataccctttc tcctgataaa gtggcagctt tttctaattc
     1081 acaataaaaa tcatcattat ttgttactat aggagttgca acatttccta acaatgttaa
     1141 agcagcacca gttaatgtag ctacatcaac tacctttgtt actttttcat tgtttataat
     1201 gtagtatatt gcatcagcta atgtaagtct accttcggca tccgtattta aaacttcaat
     1261 agttttcttt gccatagaac taattatatc tccaggtttg tatgaacctc ctgataaagc
     1321 attctcacat gcagccacta ctgctataac atttttcttt aatttacttt gagatatagc
     1381 acacatagca cctataacac tcgcagcacc agccatatct gtcttcatat ctagcataga
     1441 agcatttgat tttaaagaat atccaccagt atcataagtc aatcctttac ctactagacc
     1501 taatatatct gtactttctt tatctccaaa gtatctcatt actatgaatc ttggtttatt
     1561 gattgaacct cttgaaacgg cgaaaaaagc atccattccc aatgccttta ttttttcttc
     1621 ttcataaaca tcaacattaa acccgaactc tgcaccaagt ttaactgttt ctattgctaa
     1681 tgtttttgga tatattacgt ttgatggttc attaactaga tttctagcta ttatagttga
     1741 attagctaat attttagcct tttctatttg acactcaact tctttttcag taaatatagt
     1801 tatagtatca acttcttttc tttcaaaatc cttacttttt gtcttatact tatcaaactt
     1861 ataatttcca agtaatatcc cttctacaaa agaacctatt tcatcactat ttaaattaag
     1921 attaagtaca ttaacatcac tactcttata tgcttcattt ttcaatatat tttttaattt
     1981 tttacacaaa ttaccaccta tgattctaat tttttctcta ttcaataact ctctcttacc
     2041 aaaaccaaca agacaaacat ttaccaagtt gttattttca accaatgtta cagtatctat
     2101 actattttct ttagaattaa aatttctgct tatcatattt attttatcaa atgtcgtaga
     2161 aacatcttct ccctcaaata gagctactac tgttatagca ttttctaaac tttttaatat
     2221 ctctttagaa tactttatat tcataataaa ttctcctttt taaaataatt gttctattat
     2281 atttttagac tcttccaaag aagtaaataa tttatcttta ttatctatat ctaagcaatc
     2341 cattttatca cttattatag atacaaactt tagtatttca ttatccaata tcttttctcc
     2401 atttttagtt attccataaa aagtatttcg tctatctcta ctatcttctt ccctatatac
     2461 atactcttgc tcaaccaatt tattaagtag tatacacaga ctagaagtag atacatgtaa
     2521 atctctactt agatttttaa gctctatttt atcatgtttt cttattttta ctaaggcaaa
     2581 gaactgtctt tctgtaagaa ccttatcttt tttatatctt tcgttattaa taatctttat
     2641 taaattatga aaattattca tactttctaa caacaaaata gataattctt tatcgctcat
     2701 aacattcacc tcaaaactaa tgatttataa ctccctctta tatctcaaat gcgtttatat
     2761 atctataata taatacttct tttcttttta taattatact atatatcaac tttattatct
     2821 atttaaattg ttttaaacta aaatcttatt agatataaat gtttaaagta cacaacaaaa
     2881 tagtgggatt tatactaacc ccactacttt acttaaaact atatacatat ttaaaaatat
     2941 tttattctta catattgttt ttatcttgat tcttattact ttgtgatata ttttgaattt
     3001 tctccaatac tctaggagtt atagataata tattatccac tagattgata ttactgtcta
     3061 aactcattat tctagtctct ccactttcaa ctactacaaa tgctactggt tgtacagata
     3121 tagcccctgc gctacctcca gcaaaattcg tatctgattt ttcatttttt aattcaattt
     3181 ccctatcttt atcatcatat ccttttgagt attctcctcc tcctatacca aagccaattg
     3241 taacctttga tataggtaca accactgtag tatctgtttt tatagggtct cctataatag
     3301 tatttgcatc tatagaacct ttaattgttt caagagttgt ttccataaga ctttgtatcg
     3361 aacctgttgc tctcattact atcaccttcc ttatttcctt tatttttatt cataatttta
     3421 ttaatcatta ttataatatt aaataaagct tttattcttg gccttatatg tatccttata
     3481 tttcctaaaa cataatcttt tgtaaaatct ggatttacat ttaaatacat tttttctgca
     3541 tcaatcatat taaataaatt tccatacaaa gtatttatca atacatatac agaagatgtt
     3601 aagccaatat ttccagttcc aaaattaata tttgaataaa gttcatgtat ttttatcttt
     3661 tttaataatc tataaatgct caaaaggtca tcagctaata atatacttga atctatatta
     3721 ttcttcatcc cctctttttt atcattattt ttactatttt cagctggata aagttgtcta
     3781 tttatattta ttaaattaaa catgtatttt atattaagct ttaaacaaat atctttgttg
     3841 tttatatcag ctattattaa gatgtttata tgagatatta aaatcaacat agttacactt
     3901 ataataaaaa ttacagctat tattaaatac ttaaaattaa ataattcatt aagctccatg
     3961 tttatattat catcaaaaaa ttactattta tacttaatta tccatattta ttttaagaga
     4021 attataattt tatatttata caaaaaaaca caacaactta gagcatttta aatcttttaa
     4081 aatttaaaat tacatactaa attattgtga ttttatattt ttattcattt gttgccactt
     4141 cttgataatt ttctataggc ggcaattctt caagactttc tatattcaac aactttaaaa
     4201 attcatctgt tgttttataa attattggtt tccctatctt attcaatcta ccagcttctc
     4261 ttataagttc attttcaaac aaagtttgta ataccttatc acattttact cctcttatat
     4321 cctctatttc tacctttgtt attggttgtt tgtaggcaat tatagtaaga gtttctaatg
     4381 tagcttggct caaacttttc tttttctttg gttcaataat cttctttata tattctgcat
     4441 agtctttatt tgtacacatt tggtacttat tctctagctt gattatttga atacctctat
     4501 tttgttctct gtactcctca ataagtaaat ttaacataat ctctatttct tttgatgaaa
     4561 gttctttatt tattatatag tttaattctt ttatacttat tggttcccca tatgcaaaca
     4621 taacagattc tataatatac tttatatctt ctcttttcat tttaacactc cgaacttttt
     4681 cttattagaa tatcatcaaa aaatatgtct tgtactacta ctatttcttt ttcttttata
     4741 agctctaata tagataaaaa agtagctatt atttcatcat tttcatatga ttttataata
     4801 tttgtaaaag taacttcaat cttatctttt ataatatctc ttatatacaa tatcttttct
     4861 tccacagata ttatcttctt ccttactatt ttgtctagtt tctcatcatt agcattttct
     4921 atctgtgatg ttttaacttt aaatatgtat ggaagtatat tttttattgc ttcaattgat
     4981 atatcttcta aatccacatt gtcatcaata attatctctt ctttatttct ataaaatctc
     5041 tcattaacat aagttatatt ttcttttata tcttgtgatg ctaccttaaa ctttctatat
     5101 tcttctaact tttccataag ttctattctt gggtcttctt cttcatcttt ttgcttataa
     5161 agcagatatt tagactttat ctctaaaagt tttgatgcca tagttataaa ttcactagtt
     5221 atctctaaat ccattttatc tagcattttc aaataattta gatactgctt agttatatct
     5281 attatagata tatcctttat atctatttta tgctttgtta ttaaatcata aagtaaatct
     5341 aatggtccct catagacttg taattgtata ttatacttca tatcaatccc tctttaatct
     5401 gtttattata ttaaacaaat aaatatacta tttttagcaa cactgtatat attggtgata
     5461 gtattatttg atatatacca gtaaataaag caattaataa aattatataa ctcatacttt
     5521 caaatttata caaatattca ttccatttat atggtacaaa tgtagatata actccccatc
     5581 catcaagtgg aggtatcgga agtaagttaa aagctgcaaa tcccatacta tatataagca
     5641 catatccagc tattgtattt atagcataca tatgcacata cttattgata attacacaca
     5701 gtatagcagt caaaacatta caaaaaacgc ctgcaagtga aactatcagg tttcctatct
     5761 tatagttttt aaaattattt ggatttactg gtactggctt tgcccaccct atcttaagga
     5821 taaacatagc caaaagacct attggatcaa catgtcttac aggatttaat gtcattctac
     5881 cataagcttt agctgtatca tctcccaata agtgagctga ataagcatgg ccaaactcat
     5941 gtattgatat tgccatagct ataccaacta aacttgctac tatttctcct atattcatac
     6001 ttaacattaa tgtacatctc ctaaattaaa tttttaatat tattataaca attaaatagc
     6061 ttataatcaa aattatttta cattataata attttaactt ctaggcataa aattaaaatt
     6121 tgctttttat tttataactt ttattattat atcatattca ttgtgaaaat ataataatta
     6181 cacctactgt aagtgtaata ttatattgac atgaattgac attattgtct cttagtcaat
     6241 attatacaag aagtataaaa aaatatgtgt tacactttgt ataacatgaa aggaggttac
     6301 ctaagtgaga caagaagaac gcacagtatg ctttgatagg gaattaaaaa ttgaagcata
     6361 tagatttaaa ggcataatgc aaaaattccc aaaccatttt catgaacatt atgtaattgg
     6421 ttttatagaa aaaggtcaaa gatatttatc ttgtaaaaat aaagagtata ccacaagtac
     6481 tggagatttg ctacttttta acccttttga cagtcatact tgtgaacaaa tagatgataa
     6541 agtacttgat tacagatgta tcaatattaa gccagaaata atgaaaaaaa ccgtctttga
     6601 aattacaggt aaaaattatt taccaaaatt taatcaacct gttatatttc gcagtgagct
     6661 agtacctcta ctacaagaat tacactatat aatcatggaa gaagaattgg attttaaaaa
     6721 ggaagagctt tttttcttcc taattgagca attaattgaa gaacatacag agccaaattt
     6781 gcaatctaac ttggaaaata caaatataga aattcaagca gtatgtgatt atctagaaaa
     6841 taattatgct gaacatatag tacttgacga attaagcact atagcaggta tgaataagta
     6901 ctctctactt cgtaatttta cgaaattaaa aggtattaca ccatatagat acctagaaaa
     6961 tatacgggta aacaaagcta aaaagctttt agaaaaaggc gtagaaccta tagatgctgc
     7021 gatacaaaca ggatttgtag accaaagtca ctttacaaac ttttttaaga attttattgg
     7081 tcttacacca aagcagtatc aaaatatatt tataaatgat gattcaaaca actttaaata
     7141 aggtaaaaag gagaaataaa aatggaaaat aaaaattcaa aatgtgtcat ggtaatagac
     7201 gaaaatttac caatgggaat tatatccaat acagcagcta taatgggaat tacactagga
     7261 aaacatgccc cagaaactgt tgggccagat gtaattgaca aaacaggtaa tagccactta
     7321 ggaattattg acattcctgt acctatttta aaaggaaaca aagaaataat aaaagattta
     7381 cgtaaaaaat tatatacttt ggaatttaac gatttaactg ttgtagattt ttcagatgta
     7441 gcacaaagtt gcaatcttta tgaagaattt acacaaaaga ttgctagtgt tccagaagat
     7501 gagttacagt attttgggat agcaatttat gggaataaaa agaaagtgaa taaacttact
     7561 ggtagtatgc ctttacttag ataattgtta aacaacccta tatatgatat taaatcaaat
     7621 gatattttaa gatacataaa cttttctata tttctataaa aatcataaga ttataaaata
     7681 cttctatatg gtaaataaaa atacccctat ggcaaataac tacataaggg tattttttat
     7741 gtgtattata atcatatctt tgtgtattat aattatattt catctgataa ttatttatat
     7801 catattatca attattcttt gaagcatttg tagatagctt gccttattta tatccttagt
     7861 atttatcaat tccacttcgc ctattacttt tttatcttta catatcttta tttttcctaa
     7921 aacagttccc tttttaattg gcatcttagg attttttact atttcaattt tcttctcaaa
     7981 ttctttagag cttccttttt taataagagc atttaaatct tctttagcaa ccaatttaac
     8041 tttgttttca tcagccttat ccaatgtaag tgttgctata ttatcacctt tactacataa
     8101 cttaacactt tcataattag caaatccata gtttaaaagg ctagaggcat cattaaatct
     8161 ttctggagaa gtctctgctc ctaaagttgc agcaactaga tgagtattac ctctctttgc
     8221 agatgctgat aaacagtatt ttgcttcttg agtaaaacca gttttaacac cagttgctcc
     8281 ttgataatgc tttataagtt tattagtatt tgcaagacct actgtaactt gtttcttccc
     8341 tactacaacc ttatccatcc atgtagttaa gtatttactt atcatttcgt gttttaatag
     8401 ttctctagac attaaagcta tatcatgagc agatgtatag tggtttgcaa ctggaagtcc
     8461 atttgtattt gcaaaatgag tatcattcat atttaactct tttgctttag cattcattct
     8521 atcaacaaat ccttcaacac ttccagctaa gtgttcagcc atagcaacac aagcatcatt
     8581 tgcagaagca acagctatac cttttaataa tgtatcaacc ttttgagttt ctcctggctc
     8641 taggaatatt tgactaccac ccatactaga tgcagtttca cttacttgaa cttcatcatc
     8701 aagcttaatc ttgcctgaat ccaaagcttc tactataagt agcatagtca ttaccttagt
     8761 tacactagca ggaggaagct ttttatgagc atccttttca tataaaattt gtccactacc
     8821 aacatccatc aaaattgctg attttgaaga tatatttagt tggttggcat cagcattttc
     8881 cttattattt gcaaaagaaa agcttaaagg agtaagcgca attaatatag ccaaagcagt
     8941 actagctaat tttttcatcg atgtcacctc ttaaagttta tttaaactta ttttctcaca
     9001 tttaactttt tttattctaa atgcctagat ataccttgac ctaaattttt tttcttttca
     9061 agctttttaa agtaaccttc taaaacacct ttattagacg cattttctat tatttcaaaa
     9121 gcatcttcat aattcattcc atactctcct gctatttcca tttttgtttg ttttaaagct
     9181 tttatagcat tttgtcttga aacatcatcc ataagaatcc tcctatcagt aaaatttata
     9241 tataagtagt ttttactaat aaaagattgt tataattggt attttatgta atatatattt
     9301 tttttaaatg agtattaaaa agacctcttg taattcttaa gataatatca attggatttt
     9361 tgatattact ttaaaaatta caagaggtct aattttcaaa tttatagttt ttttatatta
     9421 tacttccatt atgataggaa gtatcattgg atttcgttta gttttttgat ataaatattc
     9481 ttttaggttt tctttaatat tattctttaa ataagcccat tctttaatat ttttctcttc
     9541 acattcattt agaacattct taattatatc ctttgctcca tccattaaat cttctgactc
     9601 tcttacatat acgaatcctc tggaaattat atctggacct gctaagacct taccctcatc
     9661 cttggaaata gtaactacaa ctatcataag accatcttct gataaatgct ttctatccct
     9721 taaaactata ttacctacat cgcctactcc tagaccatca actaatatgt ttcctgtttg
     9781 tatacggttt gctaccttag cagagttttt atctaattct aaaacatctc ctgtttgcat
     9841 gacaaaaata ttttctttat ccataccaag ctgttcagct atttcagcat gtctttttaa
     9901 cattctatat tcaccatgag ctggcataaa aaactttggt ctaactaatg catgtataag
     9961 ttttaattct tcttgacagg catgtccaga aacgtgtata tcagctatat cactgtatac
    10021 tacttctgct cctttttcaa ataagaaatt gattactctt gatattaatt tttcatttcc
    10081 tggtattgga tgagcagata ttataactaa atcgccactc tttatttcta cttttttgtg
    10141 ctctgaaaaa gccattctag caagagctga cataggttca ccttgtgaac cagttgttat
    10201 tatcactaat tcactatctt catacttaca tatatcattt aaatctataa gcatgtcatc
    10261 agaaatatct aggtatccta attcttttgc aactccgact acattgacca ttgagcgacc
    10321 tgatatagca acttttctat taaacttttc agcagtattt attatttgtt gtaatctgtg
    10381 tatgttggat gcaaaggtag caactataat tcttctgcca tttccttttg caaataattc
    10441 gtcaagacct accccaacag tcttttcaga catagtaaat cctggttttt ctgcattagt
    10501 actatctgcc agcattaaaa gaactccttt tttgctcaac tcacagattc tatgcatatc
    10561 cataacatct ccatcaatag gagtcaagtc aatcttaaaa tctcctgtgt ggtatattat
    10621 accttggtct gtgtgtattg caatagagta agcatctggt atactatggt tatttttcaa
    10681 aaactctact tccatattat caagctttat aacttgtcta ggacctataa catttaactt
    10741 aacattattc attttatgtt ctttaagttt tacttgtata agacctatac taagtcttgc
    10801 cccatataca ggtacattta ttttctttaa tatatatgga agagctccta tatggtcttc
    10861 atgtccatgt gtaataaata taccctttat tttatcccta ttttttacta aataagttat
    10921 atctggtata actatatcta ctcctaacat ttcatcctct ggaaaactaa gtccagcatc
    10981 tataacaatt atttcatctt tatactcaac aacagtcata ttttttccaa cttcgttaag
    11041 tccacccaag gccattacct ttatcttgtt ggtgttcttt ttgaacaatt gcatcatctc
    11101 cttctgtcta tttaattttt taacacgttc tacaatcata aataatatca aatcacgcac
    11161 tcgctaccag ttattcttat tgtaccataa ttcgtatcat attttaagct atatttaaaa
    11221 tacatttaac gtattatttt gacaaaccta ttttattttg atatcctcta aatattatat
    11281 gatttaatat cggataattt aggaggattt atgcgtggta aaactcattg tgcaatagga
    11341 atcttaacag ctatccaaac atctttaata tttaaaattc ctatatcttt agttgatatt
    11401 ttagtttcag ctacttttgc tgtactaccc gatttggata aatctaattc tatggtctca
    11461 aatttcattc taaaaaacaa tgtatccaaa tacatatata gaatttttat atatgctgtt
    11521 aatattatta ttttctttat ttcaataaat ataaatgata atttttattt aagcgcaata
    11581 attacatttg ttgcaattat aattattgaa gcaaaactaa cccacacatt tctaagaaaa
    11641 gtttttctat cattaatatt tatactatta gctatatgct tatacatcat agaagttgaa
    11701 atatatttta caattttttg tctaatgttg tcaatttttc cctggttaaa gcacagaagt
    11761 ttttctcata gcatatttgc aactataata gtatattttt tactaaaaca gatagaatta
    11821 atcactaata ttaataattt atctttttat ggtacgattg gttatgcaag tcatatgttt
    11881 ttaggagatt tatttacaaa gcaaggaata ccaatttttt atccgctaag cgaaaagaaa
    11941 atttctttag gttttttaac tgttggagga ccatttagta atttcataga aaaatcattc
    12001 atttttgtac ttataggatt aattatattt tcaatattaa aactataagc atcttgaaaa
    12061 ctgtatattt gcattttgta gatggtttat aataaaaaat ggaagaatag catagaatat
    12121 aaaagttcta tactattctt ccatcgacat taagcaatag aagtttattc ttctgaatcg
    12181 cttactccat tacactcgtc acataatcca taaaatttaa catcatgatc aagtatttta
    12241 aatttgtaca atgattgtat ctctttttct atattgtcta aaaggtcttc tttagcttcc
    12301 attatctttc cacaattttt acaaataaga tgatgatgat tatgacagtc ttctttatgt
    12361 agactaatct catatcttat acatccatcg tctaagttta gttttgatat taatcctatt
    12421 tcatccaata gctgcattgt tctatataca gtagctaagc ctatttcagg acagtcaacc
    12481 ctaactaaat catagatttc ctcactactt agatgtgaat ggtcatgttt aagcaatatt
    12541 tcaactattg ctcttctttg tggcgtaatc ttaaaaccag tttcttttaa cttgtctttt
    12601 aataaatcca ttgtatttgc cataacatca cccttactat tttcaattga taatctttat
    12661 taaataatat tgtaattgat aattcatttt ttgtcaagac atttaaataa atttaattta
    12721 ttctcataat ataaatatat acccataaaa gatatattat tcaccaaaat tcataaattt
    12781 tttggtattt ttaataaaaa acaaaaaaac agatatatac tataaatgct tttacaatta
    12841 ataaggttta attaaagcaa atataataaa tatctgattt ttatatacaa acttaattac
    12901 ttatctagtt aagtccattt gattcatctt cgtcgtaatt taaaccttct tcttccatta
    12961 tagcagtata cacagctaca acagtttcat actcttcatc actttccaaa ggtattaata
    13021 tttcaccttc ttcatcctca tcaattctaa agattaaagc ttcttcagct tcttcatcat
    13081 ctaaaggcat taatattgca tactcttttc cttctgcttc taatgttaat attatttcaa
    13141 attggctttc aacgccattt tcgtctatta aatttattat attttcttcc ataatgtcat
    13201 tcacctcaaa tttattttta tttttattat ttatattata tatcataagt attcaatttt
    13261 atagttcttt tatgaattta ttttaaaatc taaatatcct tgcaaaatta ttactgctgc
    13321 caacatatct ataacctttt ttcttttttg tctactaaca tctgcttcta ataaagacct
    13381 ctctgccgct actgtagaaa gcctctcatc ccaaaactct acatcaatac ctgtttctgc
    13441 ttttaccaat tcacaaaact tgattacttt ttctccttgt ggacctaaag ttccattcat
    13501 attttttggt aatcctgata caattttatt tacttgtttt tcttttatta ttgcttttaa
    13561 ctcttcaata tcttttttct tgccaactct ttttattgtt tttacacctt gtgcagttaa
    13621 tcccatcaaa tcactcacag caactccaat agttttatca ccaacatcaa gacccattat
    13681 tcttccatct aacatagttc ctcctttatc tatttatatt ctatagatta aatacatatt
    13741 ctgaacctct cataactaag gtcacaggct tcctgcttca tagaattttg cataatcaat
    13801 cataaaaatt gcaatatgat tttttatgta agcatccagt ttacattaat aatcatattg
    13861 cattttttat ttaaatccta tatgaacagt aaaaaatttt ttagttgttt ttttcaaata
    13921 ttatcatatt tatatttatt attattagtg gtataagtat atatatagat gctgtagatg
    13981 cagcaactat tccagaatca ttaactaaaa gagtaattat acaaccaacc atagatgcaa
    14041 taaacccttt aaacaagatt ggaaaattat tcattatctt tctaaagtgt ctagatggtt
    14101 taaatataag tactgcaatt actccaattc ctacaagtaa aatatttacc catacacttg
    14161 tctgtgctag ttgcatattc atttgaattt ttcttccaaa tgtttgtaat atctctcctg
    14221 gtccatttag gaaaattctc tgtacaaaca tacctaaatg agattcacta cctgaaagta
    14281 tatctaaagc tgcaaatgca aaaacgacaa ctacagctga aacagctaat aatacagctt
    14341 tcttaaaatc tattttaatg tcatatataa gcattataaa caacaaatat gctacacatt
    14401 ctgatatagc tccaccaaca tttgcaccca ttgaaggata tgcactagtt ataagtatta
    14461 ttaacgaaaa aattacaaca agtaatttag ataccttctt ataatgtaat aatactgcta
    14521 agccaaatac tgcacttgct atagttacac cttcatattc atttcctaca ccatagtacc
    14581 tagctcctat gacagcatca taactcatta tgttattttg cattaagtat gttccaaata
    14641 cagaatctat aactatgact aaaatagtaa gtgttgcaaa aaatcccatg tgctttatat
    14701 cattgtcctt aaataatttt ctacctaaca agtataatat tagcgtagtc gcaaatattc
    14761 ccaaagatat tgaaattgga gttttaaaat tcatcaaagg agctaacata aatgatagtg
    14821 gcattattat gcctaatttt ataaactcct taagtacttt gaatacacgc tctttatgtg
    14881 gcatataatt tctaaagaaa atcgcaaaca tggcaattac ccaagaagca gatattacgc
    14941 ctacaaagcc atttataata gttgacctta ttgaagatat agacactatc ctttcataaa
    15001 gtgattttag atagccaaca ttgtcctctt tatttactaa agtataactt ctacctacca
    15061 tctctttatt ttcaagacca aatgtaccta gtatatctac tccaacatct aaattggcaa
    15121 caattccagc ctttcttgtt gtggcagatt ccagtagacc tttcccttct ccactaaatt
    15181 ttattattgg agaaagtctt ctcttattct tataatctag gtcacttgga aatgcacttg
    15241 ctatataaac agtgtcattt tctccaacca tagaaaatac ttgttcaaga tatttattta
    15301 tattttttac aatatttttc ttcattgtac cataagtatt atcatttaga tttaatctat
    15361 acatatctaa tctatatgta tctccaagtt ctacaaatat agcatcacta tttttatagg
    15421 attttttagt ttcatctagt aatttatcgt agtctgtaga tattccaaat ggcattttag
    15481 aatctttctt attaatatta tcaatattac ctgaatcaat ccttccatat tggtccatag
    15541 ctactaaaca taagtttcta tttttaacta attgattatt ttcaattata tcagcatttc
    15601 caattacaga tgtctttaaa ccattttctg ataaagtttt tcctaatgac cctaaatttg
    15661 ctccatattc tccatactca agattttcat ttatagatct attaatgcct aaatcattta
    15721 tttctttagc tttttgacct gttgcgactt caaaagcttt agcagtatct tggtctactt
    15781 tttgaaaatt gatatagtct tcagtagtta cactagctct tgttcctgca cccatacttg
    15841 cataagacct tctatcatca gtaccttgat cccctcttat attcatgaga gctacatagc
    15901 ctctcttttc tatctcattt ttcaagattg gaatattcat catacttcca agattggtcc
    15961 tattcatatc aataaatatg accttgcctt tttcttcagc aaaaccatag ctagcagttg
    16021 atacaaaaat cataatgact attgcaaaca acgacataat cttttttctc atttatttga
    16081 cctactttct attcagatag tgcgtgatta cttcttcaag tatctcatct ctttcaaatt
    16141 ttttaattat agctcttgca tttttatgac tagttatata gctagaatca ccagaaagga
    16201 gataccctat aatttgattt atagggttat atcctttttc aactaatgct ttatatacaa
    16261 aatcaatagt atctcctaca ctcatcctat cttctggtat tccttcaaat ttcatagtgt
    16321 agtctaaatc tttttccaaa ctaaaaacct ccttgagtga atgttattta acttgtgtct
    16381 taataacctc acttgcatag cttaaagctt ggtcaacctt agatacatca ctagctcctg
    16441 cttgtgccat attaggtctt cctccacctt ttcctccagc tatttttgca acttctctaa
    16501 caatattacc tgaatgtatt cccttatcta atacatcttt agtggcagta actacaaagt
    16561 taactttatc atctactaca tttgcaagta ctactacacc agaaccaagc ttatctctta
    16621 gattatctgc tgtttctctt agtgtatcca tatccatacc ttcaaattta ttagttatca
    16681 aattaactcc atttacttca actttagaat caaaaataga atcaactgat tgtaaactca
    16741 tcttagcttt catatcatgc aattctttag ataagttttt attttcttct aataaagaac
    16801 ttattctttg aattaaatta tcttctttag attttaagtt tacacaaact tcagagataa
    16861 ttccatctct ttcttttagg tattcataaa cagcttttcc tgttattgct tctattcttc
    16921 ttacacctgc tgctactcca ccttcagata atattttgaa cattcctact tgagaagtat
    16981 ttgtcaagtg agttcctcca caaagttctg tagaataatc tcccatagaa actactctta
    17041 cctcatcacc atatttttca ccaaatagtg ctgtagctcc tttttcttta gcttccttta
    17101 tattcataat atcacatttt atgtctaaag atgataaaat aacattattt actttttctt
    17161 ctattacttt taattcttca tttgatatcg cttcaaagtg agtaatatca aatctaagtc
    17221 tttctggagt tactaaagaa ccagcttgat taacatgttc tcctaatact tctcttaatg
    17281 ccttatgaag taaatgtgta gcactgtgat ttcttgcagc tgacattcta gtttctctat
    17341 ctacgagtgt ctttactttg tccccattac ttattcttcc tgattttatt atacctatat
    17401 gttttatact attattagca ccttttttag tatttaatac ttctaaaact aagttttcat
    17461 tagttatcaa tccacaatct ccaacttgtc ctccaccttc aggatagaaa gtagtgttat
    17521 ctagtactat agatacctta tcgccttctt ctgcactttg aactagctca tcatctttaa
    17581 ctatagcttc aatagttcct tcaccataaa tttcactata cccattaaat gtactgtcaa
    17641 ctgtagattc taattttgat agagggtctt ccttccaact ttctccatcc atatttcctc
    17701 tagcatttct agctctttct ttttgctttt ccatttcttc attaaaagct tcttcatcta
    17761 cagatagatg ttcttcttct aatatttctt tagttaagtc tatagggaag ccataagtat
    17821 catatagttt aaaagcttct tgaccactta ggacagtctt tccttcattt tttaatactt
    17881 ctatataaga gttcaatatt tctgttcctt ggtctatagt ttcattgaat ttttcttctt
    17941 ctattccaac tactttttta atataacttt ctttttcaac taaaactgga tatgctttat
    18001 catttacctt tataacttca tctattagtt tctgtaaaaa taattctttt actcctaata
    18061 acttaccatg acgagcagca cgtctaagga gtcttctaag aacatatcct cttccttcat
    18121 ttgatggaag cactccatca ctaactaaga atgttacagc tcttatgtgg tcagttatta
    18181 ttcttattga tatatcattt tttggattct ctccatattt tactcctgtt aacttctcaa
    18241 ctgcttctag tatagattta attgtatcaa cttcaaagat agtgtctacg ccttgcataa
    18301 tacatcccat tctttcaaga cccatacctg tatctatatt cttgttttct aatagactat
    18361 aatttccttc ttcatctcta tcaaattgag taaatacatg gttccaaaat tctaaatacc
    18421 tatcacaatc acagcctggt ttacagtctg gattgtcaca tccatattct tctcctctat
    18481 caaaatatat ttctgaacaa ggaccacaag gacctgtacc tatttcccag aaattatcat
    18541 cttttccaag tctaaccatt ctttcttctg ggaaattcat ttcttttgcc catatatcat
    18601 aagaatcatc atcttcttca tatacagtca cccatatctt atcttctggt atatttagcc
    18661 attctgtaac aaattcccat ccccatttga ttgactctct tttaaagtaa tctccaaatg
    18721 agaagttacc catcatttca aagaatgtag catgtcttgc agttatacct acattttcta
    18781 tatctcctgt tcttatacat ttttgagatg tacacattct cacacttgga ggtacttcta
    18841 cacctgaaaa gtagtttttc aaaggtgcca tacctgagtt tataagtaac aaactcttat
    18901 cattgtttgg tactaaagaa taactatttg ctacataatg accttttgac tcaaaaaatt
    18961 ctaaaaactt acttcttatt tcatttaatc ccatcttttc catatcatgt tcctcctaat
    19021 aaattttatt ttttcgttta aataaaaaac ctcgtcccta taaataaatt tataggggcg
    19081 aggacaatcg cggtaccacc ctaattatca tacaaagtat gatatcttcg gaaaacctta
    19141 gctataacgt aactaccgtc aatctctact taaatcttct ttataaaaga taaattgttc
    19201 aagattgcta ctaaaaggct gcttcaaata tcatattcta agggcttcca gcatttccct
    19261 ctctctgtaa gacatcaaat attttactat tccttatcac tgtatttgtt ttttaattaa
    19321 tatactaatt atattactaa attttacaaa attaatcaat actatatttt aatatacaat
    19381 aaatttattt tataaacttt atttactctt aatatacttt attgcttatt tttttaattt
    19441 tttagatgtt tttataaact tttctcgatt atacctccac ctactacaat atctccatca
    19501 tacattacta cagattgacc tttagtaata gctctttgag cttcatcaaa aactatttta
    19561 atagtatctt ctcctactct atgaatagta gctggtgatg gttttgctga atatcttatt
    19621 ttggcttgaa ctcttaaggg ttcttctaac gtatctattg atataaagtt aacatcttta
    19681 gcaataagtt cctttttaaa taaatcttca ttgtctccaa gaactatggt attatttatt
    19741 ggatttatgt ctattacaaa cattggtttt ccaaaagtaa ttccaagccc ttttctttgg
    19801 cctatagtat aatataatat acccttatgt tttccaagta tattgccttt agtatctaca
    19861 aaaaaacctt cttcaatacg ctttttagaa tgttttttta cataatttgc atagtcatta
    19921 tctttaacaa aacaaatttc ttgactatca ggcttattgt gtactgccat ccccatttcc
    19981 ttagcaattt ctcttactct atctttttca tagtcaccta ttggcaataa agtatgctct
    20041 agttgctctt gtgtaagatt ataaagtgca taagtttggt cttttttatc tgtaacagat
    20101 ttttttagca aatatcttcc tgtactttca tccttttcta tctttgcata gtgacctgta
    20161 gctacataat cacaacctat ttgtctagcc ttcttataaa aatcatcaaa ttttatatgt
    20221 ttattacaag ctatacaggg attaggagtt tttccttcca aatattcatc tataaaataa
    20281 tctattactt tttctttaaa cacttctcta aaatttaaaa cataaaatgg tatacctatt
    20341 ttatttgcta cccttctagc atcttcaaca gcagataaag agcaacaacc accttcaatt
    20401 tcaacaacat catcatcttg ccacaacttc atagtaacac caatgacatc atatccttgt
    20461 tgttttaaaa gatatgcagc tacagagcta tcaactcctc cactcatacc tatcattact
    20521 tttttattca taaacaaatt tcacctcatc ttttgcatta cttattatta taccatatag
    20581 agcaagtatt gtacttattt aaaatatagc ttgttctatt ttctaaaaaa ataatcatct
    20641 ttattatttg aatcttatgg attattttgt taactaatta acctctaaat caagttaaaa
    20701 tacttaattt aggcaataaa aaatagccat tttaaaaaca gctatttttt atgtcctaat
    20761 tatatcatta gtacttcttt ttaatcattg taaacttctc ataacacaat cacttatttt
    20821 tattcttctt cttcaacatc atggtcatga gcatcatcta taacatatcc atccaattct
    20881 ggtatatgga tattgttctt ttgagcataa tctataagag ctgcttttac agcttgttca
    20941 gctaaaactg aacaatgcat ctttactggt ggtaaaccat ccaaagcttc tgcaacagct
    21001 ttatttgtaa gttctaatgc atcttttata gtttttcctt ttatcatttc agttgccata
    21061 gaagaacttg ctatagctga accacagcca aatgttttaa acttaacatc ctttattaca
    21121 tctccatcta tgtctaaaaa tatcttcatt atatctccac atgtagggtt tccaacttca
    21181 cctacaccac ttgcattatc aatttctccc atatttcttg gattcataaa atgttccata
    21241 actttatcac tatattgcat tatcttttcc tcctactcaa tttatgtcta ttttttatgc
    21301 tttatctttc tgtctatttt actaaacctt gtttcttcgc atcatcataa agtggtgaca
    21361 tgcttctaag tctttctatt acttttggta agttctctag tatataatct atatcatcat
    21421 ctgttgtaaa atctccaact gtaagtctta atgaaccatg tgctatttca tgtggtaaac
    21481 ctattgcaag aagtacatgt gaagggtcta atgaaccaga agtacatgca gaaccacttg
    21541 aaccagcaat tcctaacata tctaataata aaagtattcc ttcaccttct ataaattgga
    21601 atgcaaagtt tgcatttcct ggcaatctat tttctaagct accatttact cttgtgtaag
    21661 gtattctttc taacacacca tctattaact tatttctaag acgagttaaa gtttctacat
    21721 gattttgcat attttcctta gctaattctg ctgcttttcc atatccaact attgcaggta
    21781 tattttctgt accagctctt ttgctttttt cttgtgctcc accatggaca aagttatgaa
    21841 gtcttacacc ttttcttatg tataaagctc ctacaccctt tggtccatat attttatgtg
    21901 aagacatact catcaaatct attcctaatt ctttaacatc tactggaata ttacctgtag
    21961 cttgtactgc atcagtgtgg aataatatct tatgtttttt agctatttcg gatatttctt
    22021 taataggctg tatagttcct atttcattat ttgcaaacat tatgcttata agtatagtag
    22081 tatcttttat tgaatcttct agttgtctta agtctactct tccttcgcta tcaacatcta
    22141 aataagttat ttcaaatcca tgatgttttg ctaagtattc acatgtatga agtattgcat
    22201 ggtgctctat ttttgaagtt attatatgat tacctttgtt tttattagca taagctacac
    22261 cctctagtgt ccagttatca ctttctgaac cacctgctgt aaaatatatt tcactaggtt
    22321 cagcatttat aagggctgct acttgttctc ttgctttatc caaagcatct tttgcttctc
    22381 ttccgaatgt gtgaaaacta gatgcattac caaaataatc tgttaggtat ggcatcattg
    22441 catccaatac ttctttttta ataggtgttg ttgcagaata atccatatac aatcttcttt
    22501 tttccattac attcatctcc aaatctattt tttaatattt gttatatcat tttctaattt
    22561 atttttgtta tagtcattta tcatatcttt aagagtaatt gaatctataa catcttctat
    22621 accctttttc atcttttccc aaactatttt tgttacacac atgtttgagt tttcacatac
    22681 atcttcatct agtacacagt cagataatgc aactggtcct tctaatacta caagtatatc
    22741 tcctactgtt atgtcttcag cattctttga aagcaaataa cctccttgag cacctctcac
    22801 actttttact agacccgatt tttttaaaga tgaaaatatt tgttctaagt actgatctga
    22861 tattttttgc ttcttagcaa taaattttaa tgatactggt ccattgtctt gatttaatgc
    22921 taattcaaac attgctttta gtccatatct acctttagta gacaacttca tatattatca
    22981 cctctatata gaaatctaat tcatactgtt ttagtaggaa ttactttcaa gataatttta
    23041 ttatacccta ctaattttgt caagattaat tttaattttt tattttgaat aaattcccca
    23101 ttttccaatg ttttcaaatc ctagtttttt atatatcttt ccagcctctt cattatcata
    23161 aaacaaacaa ggaattttgt tttctctcag taactctgaa catagtttaa ttaggcattt
    23221 tgtagcaagt cctttagctc tatatttagg atgtgttcct actccaatta tcattgcatg
    23281 agtcctattt tctgaagtac tctttgccat tgacaccacc tgtttgttaa tctctataca
    23341 atatcctcta cctgtcctta gtccattttt taaattctct aaagttgtac tgtgaaattc
    23401 atctattaag tcataaagtt tcactgtctt ttttagattt ccaagcctaa ttctcttaac
    23461 ctttgcatta caattattat ctatcaaaaa ctttttagtt tgaagtttgc aaaaatcaac
    23521 tacctttaaa ttattaagtc ctaatctctt tgctaaagta tctacagcac atattttccc
    23581 agatatttct tcgtaattag tattacgaag tagattataa aaaccttcaa catcatactc
    23641 tccatcagaa taaaacatca taaattcaaa atatttaagt aatattgcct ttatttcacc
    23701 atgttcaccc acgtctgccc atatatttaa aaaattattt ccatatccat atctttcaat
    23761 atcccctatt ataaacaaat tgtactcagg ttcttttttt aagtatttca taactctact
    23821 gtgataagtt gagttaagtt ttataatcat aatatctacc cccgatacat aaaattcagt
    23881 ctaaaaatca ctatttagat attctaaata tttttttata tttttctcag ttttattttc
    23941 ttgtggtatg taataaatac tatcttttat gctatctggt aaatactgtt gctttacata
    24001 atgattttta aaattatgag gatatttgta tccacaaccc ctacctattt ctttagaacc
    24061 agaatagtga gcatccttta tactatttgg tatatcctta acaaactctt tatccagttc
    24121 atccatagct ttcattattg ctatacatgc agaattagac tttggagatg tagccaaaag
    24181 aatagtagct tctgctaatg gtattttcgc ttctggaaat ccaagttgca tagctgagtc
    24241 tacacatgcc tttacaatta caatagcatt tggataagct aaacctatat cttcactagc
    24301 tattactaaa agtctcctac atatacttat caaatcccca ccttttataa gtcttgctag
    24361 atagtgtata gatgcctgtg ggtcacttcc tcttatagat ttttgaaatg cacttaaaat
    24421 atcataatga ctatcaccat ttttgtcata gtttataatt ttattaaatg tagatgccct
    24481 tattacatct gaatctatat aagttatatt atccttattt ggtttagttg aatagactac
    24541 cacttccaaa atatttaagg ctcttctcat atctccatca gaaagaattg ctatatcttc
    24601 aatagcatta ttattgcact caatatccat atagctatct tcatttaata cttcaacagc
    24661 tcttttcagt cctttttcta tatcaagttt ttctaaaggt ttaaattcaa atacagtaga
    24721 cctacttaaa agagctttat atacataatg atatggattt tctgtagtgc tagcaatcaa
    24781 agttatactc ccattttcca taaattctaa tattgattgt tgctgttttt tattaaaact
    24841 ttgtatttca tctatatata ataggactcc atttacatta tttatacttc caagctctga
    24901 tatcaccttt tttatatctt ctaaagatga attagtagca tttattttat agaagctttt
    24961 attgcttctt tctgctatta tttccgctac tgtagtttta ccaacaccag gaggaccaaa
    25021 aaatatcata tttggtaaaa aattagattg taatatctta gacaatattt ttccattacc
    25081 tattatatga ctttgaccta ttacatcatt cattgttttt ggtcttattt tatctgctaa
    25141 aggcattttc tcactccttt ttaatatact tatcattacc ttaataattc gtctaaaaaa
    25201 ggtatctatt tgaaatagat accttttcta atctaaacct ataaaatata gattattgat
    25261 tgttttttaa tttttttaat tcatctgtaa gtttgtcatt aagtattctt atatgagtac
    25321 ctttcatacc taatgatctt gattctatca cacctgcact ctcaaatttt ctaagtgcat
    25381 ttactattac agacctagtt ataccaactc tatcagctat cttacttgct acaagtagac
    25441 cttcttttcc atccaattca gcaaaaatat gttcaactgc ttcaagctcg gagtaggaca
    25501 gagtgcctat tgccatttga actacagctt tctttctcat ttcttcttct aattcttcac
    25561 ctattgctct taatatttca agaccaacaa cagttgcact gtattcagct attactaaat
    25621 catcatcatt gaatgaattt gaatatcttg aaagtaccaa tgttcctaat ctttgaccgc
    25681 ttcctaatat tggaactact gtagtatatt tttgtaatct tccatgttct tcaggaaaga
    25741 tttctaatat cttctcacca tttaaatttt ctaatgtttc atcaattttt aacacatttt
    25801 gagtatattc atctgaaaat ttcttttgct tagtatactc atcttctata actgaactgt
    25861 cttgaacatc atttaaatga agacctagta ctttaccttt tgcacttact acataaacat
    25921 tagaacttaa aacgtcgccc aatgctccgg ccagtaaatc aaaagagaca ctgcttccac
    25981 cacttgtttg taatgtttta tttattttcc ttgttttttg taacacttca cttgccattt
    26041 aatcatctcc tcatgaaatt taggcctttt aataaccttt tatattttct aatattattt
    26101 tcacatttaa tgaaaattta tttttctatt agttgtttac acttgaaaga ttatcataga
    26161 ttggaacctt tttcaagaga attatgtgat ttttttcaat tttcactctt ttccgtcatt
    26221 atgctctttt gtctctttat tacattcttt attagaacac actgtttttg tttcagattt
    26281 agtcactttt tcaaccatat atgaaccaca cttctcacaa aactctcctg ttggcttatt
    26341 ccaagctaca aagtcacagt ttggataatt agaacaccca taaaaagctt tacctctttt
    26401 agattttcta agtataatat ctccttcttc acattttgga catttaacac caattttatt
    26461 cataattggt ctagttgttt tacaatcggg atagttttta caagccataa actttccaaa
    26521 tctaccatat ttgataacca tattagaccc acagttctcg caaatctcat cagtttcttc
    26581 atccatattt actttttcta tattttcaag agcttcttca atagcctctt taagtggtgc
    26641 atatgattct gatacaatct ttttccaatc tgtattgcct tcttctataa catcaagttt
    26701 actttccata tcagcagtaa aatctacatc tataaattta tggaaattat tttccaaaat
    26761 atcagtaact attattccaa gttctgttgg acatagactt gttccttgct tttcaacata
    26821 ctctctattc agtatagtag ctattgttgg agcatacgta cttggtctac ctatacctag
    26881 ttcttctagt gtttttacta aactagcttc tgtatatctt gctggtggtt gtgtaaaatg
    26941 ttggtctggc aatatatttt ctatatttaa tatatctcct ttttctatac ttggtaaaat
    27001 tttgtcttct ctttctgaaa aattatatac cttggtataa ccatcaaatt tcatttttga
    27061 accagttgcc ttaaatacaa tatcgcctat tttacattct acatttagta tatcaaacac
    27121 tgaatcttcc atttgactag ctacaaatct tctccaaatt aaattgtata acttgtactg
    27181 gtctttgctc aatgaggctt ttatactctc tggagttcta tcaactgagg ttggtcttat
    27241 tgcctcatgg gcatcttgaa cctttttagt atcctttttt tcttttttat caccagtgtt
    27301 tttatagtag ttttctccta aattgtttac gatataaccc ttagcttttt cttttgcttc
    27361 atcagatatt cttttagagt cagttcttat atatgatata agaccaacag taccttcacc
    27421 ttctatgtcg ataccttcat ataattcttg tgctatcatc attgtttttt tagtagtaaa
    27481 aaataactta tttgctcctt cttgttgaag catacttgtt gtaaatggtt ttggagctga
    27541 tttacgtctt gatttagatt ctatcttctc aacctttaaa tctttacctt ccatttcttt
    27601 tagtatttca tttacagctt cttcattttc taattcaatc ttttcatcat ttttaccata
    27661 aaatttcaaa gttatatctt tgtcttttac tgtcttagcc tcaacatcta ttgtccagta
    27721 ttcttttgga ataaatgcct ttatttcttt ttctctatca caaattaact ttgttgtaac
    27781 agattgcact ctacctgcac taagaccttt tctaaccttt tgccataata taggacttat
    27841 ttgataacct aaaagtctgt ctagcactct tcttgcctgt tgtgcatcaa ccaaatttat
    27901 atcaatattt ctaggatgtt taattgcttt tttaattgca tccttagtta tctcattaaa
    27961 ctctattcta caatcctcag attcatctaa atttagtata tgagctaaat gccatgatat
    28021 agcttcacct tctctatcag ggtcagttgc tagatatact tgtttagatt ttttagcttc
    28081 tttttttaat tcttttatta catcgccttt tcctcttata tttatatatt gaggttcaaa
    28141 attattttct atatctacac ctaatttact tttaggtaaa tctctgacat gaccaactga
    28201 tgctttaact gtgtaatgac ttttccctaa aaatttttct atagttttag cttttgcagg
    28261 cgattctacg atgactaatg ttttggccat aaaaccatac acccccacta cctaatctta
    28321 atttatacat ttaaactgta cgttttatta ttcatttcta ctactaactc atttagtact
    28381 aattcattga ttattgaatt tacatacttt atttctatac cagtataatc acaaatacta
    28441 tctatatgca agtttccttc tctttttata gcttcaatta tttgcttaga cttggcattt
    28501 agacttatat tatcatattt ttgatttatt tttttatcaa taatattaaa tatgttatat
    28561 tcatttaaaa tatcatctat attttcaatt aattttgcac cttcttttat aattttatga
    28621 caacctctac tcatttgaga atttatatta ccaggtattg caaaaacatt ttttccatgt
    28681 tcaagagcaa aatctactgt gattagtgca ccacttttta ttgctgcttc tacaacaact
    28741 actccatcac ttaaaccact gataattcta tttctattag aaaaatggta cggggctact
    28801 gtcgagttaa tattatactc tgataataat aatcccccat tttctaatat tttatttgat
    28861 aaatgtaaat tttgttttgg aagaggattg tctactcctg aaccaagtac tgctatagtt
    28921 ttagattttc cactcataca acctatgtgc gagtatgcat ctattcctat agctaatcca
    28981 cttactatat taactccata ttgggatagt tgacaactta ttgtttttgc acaattaatt
    29041 ccataggctg taggttttct tgaacctact atagctatat taaaattatt attaactaaa
    29101 cctatgtcac ctttgtagaa taataacttt ggagcgttgt atatattctt taaattttca
    29161 ggatattctt tatcatattt acaaatatat ttaatcgctt ttttgtaaag tagttctttt
    29221 atattttcta aataagcgta acctctatat tttactatat tttttctaat attcaagctt
    29281 atatttttta aattatatat ttctttttca gaaaaatcaa atatatcttc aatatttact
    29341 atttcatttt ctattatttc aattgttttt gttgttattc caccaattga ttttaaccat
    29401 aaataagtat ctcttttttc cataaaatcc acctcaaaaa actatttaaa ataactataa
    29461 taagcctttc taaatgaaaa agcttctata atacactgtg aatttatcaa gtctctttct
    29521 tctaaatctg ctattgttct tgccattttt aaaagttttg tataacttct actgcttagg
    29581 ttgtatttat taaatatcat ctcagccgtt tttgaagctt ctttttccag tttacaatat
    29641 ttaaataaat tgtaagcttt aatttcacta ttatttttta tattatcttt cttaaatcta
    29701 tttatctgta tttttctagc attttctact cttctcttta ttttttgaga gctttcttct
    29761 tgttttaaag aattaaaatc tgaatatttt atagaattaa cttctacaaa aatatcaaac
    29821 ctatctaaca atggacctga tattttattt atgtatctat caatttcgtt acttctacat
    29881 ctacactctg tctctgacat ataataacca catggacatg gattcatagc tgcaactaac
    29941 agtactctac aaggatattt tgcactgtac tttactctgg atatatttac atatccatct
    30001 tctataggtt gtcttaaagt ctcaagtatt tttctatcaa attcggctat ctcatctaaa
    30061 aataagatac ctctatgtgc taaagcaatt tctccaggtc ttgcatccat tcctcctcca
    30121 attaaagatt gctttgtagt tgtatgatga ggtgctctaa aaggtctttt atcaattatt
    30181 cctttacttt catttatcat acccaatata ctataaacct tacttacttc tatcatttct
    30241 tctatactta tatctggtaa aattgtcctt actctttttg caatcatagt ttttcctgag
    30301 cctggaggtc caatcataaa catattatga tttccagctg ctgcaatttc tgcactcctc
    30361 tttacaaaat aatttccttt tacatcttta aagtcttcat catatttact ttcttcatta
    30421 ttaatcttag tatatttgca atctatataa ctattatctt tttctaattc tccgttctct
    30481 tttcttgact tatcatccaa aaaagacatt atacttactt tatcgacttt tatctcttcg
    30541 tttaaaaaat cgacacattc ttttaaactt ttaataggaa ttatatcaat ttcatctact
    30601 aatagacttt cttttatgtt ctcaattggt ataaaaatac gttttatgtt ctgagttttt
    30661 gcacccataa ttatgggcaa tatccctctt acttttctta tttttccatc taatgataat
    30721 tctcctataa acatactttc tcttatgtaa ttttcatctt tttttattaa ctctcttaaa
    30781 aggcctatac ttatagataa atctaaaaaa gctccttctt tttttatatc tgctggtgat
    30841 aaatttacaa ctattctcgt gcttggaaat ttatatccac tattaagaat tgctgacttt
    30901 actctttctc ttgcttcttt aatttctttg cctggaagac caacaatatt aaaactaggt
    30961 attccattgc ttacatctac ttcaacctta actaaaaagc tgtcgattcc tactaagttg
    31021 cttgaattaa taatacttaa catatttaat cctttccaaa aacattatct tttttaaaaa
    31081 gcattcatta tgtgatttat tcttttttct aacaaataga cctctatgat gtcaaatctt
    31141 atgggagtat tatttaagtt attttttata atatagtatt ttgcgacacc aattatcttt
    31201 tttctttttt taaaatctac agattcacaa gggtagccat actttatgtt agaccttgat
    31261 ttcacctcca caaatacaac ttcatctcct atatttgcta ttatatctac ctcccctatc
    31321 cttaatctat aatttttttc tagtatcttt gcaccttttg atagcagata attaactgct
    31381 atttcttctc caaaatcacc tttttcttta ttattcatta tctactccaa tatattaaat
    31441 ttttactttt aaattatcgt cagtatacaa tttaactatt caattttttg aaattgattt
    31501 tatttccatt gatattaata aatacttcta ttgactttat tcttttatga tattatgcta
    31561 gtttttataa tgaaagttta tttttatgga ggaatgtctt taatgaacag aaaaaaaaca
    31621 tttattttta tacgatattt atctctattt atattactta taagttattt aaaccatact
    31681 gaaaatacat tgtatccagc tataacaatg attatattat ttctaataat aaataatcaa
    31741 gttagatttt tttctttatc aagtgagaat aaatttatac ttatttctta ttttttagag
    31801 cttattctaa tttttatatt ttgtaagtat ataaagactt ttaatccact ttactatgtt
    31861 tctttaattt tggatgcctc atttttaata aaggaaaaat ataaatatat attattctct
    31921 ttagttataa tattttcttt tattattggt ttagataaaa atttatattt agcactagaa
    31981 tcaagttcta cattactaat tataaccctc ttttctgtgt atctagaaaa cgagaattta
    32041 tctaaattat acaatcaaag tctttatgac aaactcaggg tttctaaaga tgaattaaaa
    32101 aaagctaatg ccgatttaga gatttatgca aattctatag aagagttagc aattttgaaa
    32161 gaaagaaacc gtatatcgag ggaaatacac gatagtgtgg gacattctct ttctacgacg
    32221 ataatccaat taaatgctat agaaaaactc ttaaaagaca aacctctcat ttctgattta
    32281 gttcatgaac ttagagagtt tgtaactgaa agttttcaag atgtgagaag agctatatct
    32341 gaactaaaac ccattgaata tgaaaattac caaaatttac ttaaaatcag agaactggtt
    32401 aatagcttta ttaaacttac aaatatcaac gttagattaa ctatatcaaa aaatacctgg
    32461 aacctatcta caaatcaatc tatcgcttta tatagacttg ttcaggaatc tctttccaac
    32521 gcatcaagac atggaaaagc aactgaaatc agaattttta taacatttaa tccttcaaat
    32581 cttataatta ctatcagcga taatggtata gggtgtaaca atataaaaag aggaaatgga
    32641 cttagcagta ttagcgaaag aatatatgaa ttaaatggta aagttgaatt cgataattct
    32701 aatactggat tcacaattag agcgtctttt cctaaatttt caggaggtga tttttttgaa
    32761 taaaatcaaa gttcttatag tagatgatga aaaattgatt agaaaaggtc ttaacattat
    32821 tttatcatct tatgacgatt tagaaattgt aggagatgct tccaatggat atgaagcatt
    32881 agaattttgt aaaacaaatg atgtagacat agttcttatg gatattcgga tgaaagtttg
    32941 tgatggagtt ctaggcacaa gacttataaa agaatatgat agctctatag cattattaat
    33001 tttgacaacc tttaatgatg atgagtacat agaagatgct atgaaatttg gggcttcagg
    33061 atatctttta aaggatagtt cggatgaagt attacatgaa gggattcgtt cctcgttttt
    33121 tggaaatatt gtacttgata aaagtgtggc tgaaaaaatt atgtaccctc aaaaaactat
    33181 agaacaaaaa catatttctg atatgtataa tttaacagaa aaagaaatat ccataattag
    33241 attaatcgca aatggactta acaacaaaga aatcagccaa gaattattct tatctgaagg
    33301 tacaataaag aataatatca ccaatatctt agggaaacta gagcttcgtg ataggacaca
    33361 actagttata tttgccttca aaaataaaat tgtaatataa atatataggt aagaaatcta
    33421 taccctagaa atttcttact cacaaactca tttataataa atgaaaatat aaagtgactt
    33481 aagtcacttt ttttagtgac ttatagtaat agaattatga ttcataattc tttattatag
    33541 tattatagat ttttaactta tacaaaatta ttttgggagg aattattatg gatatagtaa
    33601 gagtaaataa tataacaaaa agatttaatg ataaattagc acttgataat atcagctttt
    33661 ctgttaaaga aggagagata tttggactta ttggaccgaa tggtgctggt aaatctacac
    33721 ttataaatat aattacaaat cttatgttac caaatagtgg cgacatccaa atcaatggtt
    33781 tagatttgtc aaaagattgt ataaaagcaa agtctataat aggattagtt ccacaagaat
    33841 tagcacttat agagactctt actccttttg ataacttaga gtactttggc acttactatg
    33901 gactaaaggg aaaattgctt caagagagaa taactgaagc cttagaagtc acaggactca
    33961 ctgatgttaa aaagaaaaaa atcaaaaaat tatctggtgg tatgcaaagg agattgaaca
    34021 ttggaatagc acttttaaat catcctaaaa tattaatatt ggatgaacca actgtaggtg
    34081 ttgacccgca atcaagaaac catattttca attttataaa aaatatatct aaaaagcaaa
    34141 aaaccacagt aatatatact tctcattata tggaagaagt tgagcatctt tgttctaaga
    34201 tttttattat ggatgaaggt aaagagattg cttttggaga taatgattat ttaaaatcat
    34261 tagtatctac aaatacaaaa ttaattatgg aaataaaaaa tataaatgct caacttatat
    34321 ttgatttaaa aaatactaaa ggtgttgtat ctattttaga aaataattca ttattagaat
    34381 taggtgtaga caaaaaatta caacttacag atgtattatc tgttgttgac aaaaataatt
    34441 caaaaataac acgaatatct tatgaagaac ctagtttaga agacgtattt ttaaatctaa
    34501 caggtaaaaa tttaagggac taatggaggt gatttcatga aattgtacat tagtgtaaaa
    34561 actatgctaa aagttttaaa aagctccttt atgcttaatt taatatattt cttagcctta
    34621 cctctagttt tagctggatt tcttgggatg gtgacagaaa gtatatttca aaatcctata
    34681 aaaacagatt tgacatcaat tgttatatat gataaagata atacaaagct atcaagtaat
    34741 ttgacaggat atctaaaaaa cgatttatct tctatattaa cagttcaaaa agatgattct
    34801 aaggcagact taaaacttac tatacctaaa ggatatgaga ataatttatt aaatgaaaaa
    34861 tcaaataatc taagtataga aaaacttaaa tctaatgata atattgcaat attacttcaa
    34921 gatatattag atacttatca tgaaaaatta tatctgaata attctcaaaa attaagttca
    34981 gaagatttct caaaattatt taataagaat tctattgata cctctataat aaaaaataat
    35041 gttaaacaaa actcttatga gtactttgct ttagtttccc ttggattctt cgcaataatt
    35101 tttataatga atagcatttt atcaaattat gtaagtgaat caaaaggact ttcaaaaaga
    35161 ctctactcta tacctgtaac tagagtacaa tttttaattt atgattttat aggtttctgg
    35221 atttactcat ttatattttt atcattatac gttttatttt ttagaacact cggtgtaaca
    35281 ttcaaaggta actttgttat attagcttta ctttgtgctt tagcttctta ttttatgact
    35341 tcaatatcta cttttataac tacctttttt agcaagaaat atggtacagt tatagtttat
    35401 gcattactct tcttgcaaac agtttttgga ggtattttca gcatagtaaa tgatgtgttt
    35461 actaagttta caagtttatc tcctacttat ttaataggaa cattgttcag taattatgag
    35521 acgtttaaaa ctatagattc aatagaaagt ttaattttta catgcctaat tgcatctaca
    35581 gtattgattg cactttctat tgtaaaagaa aaatataaat ggagggaggt ttaataatga
    35641 ttaggttgac tattgcaaac ataaaaagat atataaaaaa tcatgctctt ttagttaata
    35701 tggttttgtt tcctgttata ttaatgtttt atcttaactt ttttactggc aactcagaaa
    35761 atcaatcaat gtacttttct ccagtagcga ttgtatccaa ttcttctgga aaatacgaac
    35821 ataagttaat agatagttct aaattaaaag aaaactcatt tggattaaac gaacaagaca
    35881 aggctatgga tctattaaaa aataataaag tttctgctgt cttcatttta gataaaaact
    35941 tttcaagcaa tatagataac ttaaaacgac ctgaggttaa atgttttaaa actgaaaatg
    36001 gtggaggtag tctttgggca gaatcacaaa tagaatcttt tattactaat tcattaaaat
    36061 taaaaataga tagaaatata gatgataaat tgaccaagac aaatataatt gataacagtt
    36121 caggtaagaa taaaaattca tttttaatag ttttcttgat atgttatttc atgtacatta
    36181 atgcagcaca tctagcttct gatttatttt cattaaagaa atctaatacc ttaaaaagac
    36241 ttgtttctac aaagcataat gatataaaaa taattttcag catattttta gggttatttt
    36301 ttactcaagc aattgtatac accttaactt tagtatgttt cacatctata agtaatttta
    36361 aattgactct aaatacattg atgattgtac tagcaaatag ttttgttgct actggatttg
    36421 tattttggat agctagggtg tttaaaaacg aaggttctat aagtcttatg tctacgtttt
    36481 attctttaat aggtttagct atatccatat ctaatatgat accatcactt gataaattat
    36541 cctttatggc taatctttca aagcttacac cattttattg gactatagat gctattaata
    36601 ataatggtaa tatattaata aatataattg ttttaattct tattggaatg gtatttgtaa
    36661 cagccggaag tcttaactta agagattttg ctagaaatta ataattatta aatctagtta
    36721 gtatgttatt ttatacaata ctaactagat attttaatat attaaatcct cttatcttat
    36781 atttttatag ccaattatat atatctatta ttctaaactt tttattatat attaatcttt
    36841 ttgacttgtc aagcatttcg tgatataata ttaattatta gataattaaa gcattgtacc
    36901 caaattgcaa tatctaaaat tcagtttgga ggtataacca tatgtataaa atcggtgaaa
    36961 gtgtaatgta tccaaaagaa ggagcctgtt atataagtgg tcttgtaaca aaggatataa
    37021 atcatcatat acagaaatac tatgaattga ctgttattta caatagtaat cttaaaattt
    37081 cgattccagt tttaaatgct gataagattg gtgtacgtcc aattatggat gaaaatgaag
    37141 ttgaaaactt tatccaatcc cttgataagg ttgattgttt atgggttttt gatagaaaaa
    37201 aacgacttaa actataccat gataaatttc attcaggaga tgtttttgag attgtaaaat
    37261 taattaagat gcttatgata caagataatt caaaacaact atgtagcaca gataaggact
    37321 ttctaaataa ggctcaaagg tttgctttgt cagaattggc tgcagcacaa tgcaaatcct
    37381 acacaattgt attagaagaa atgaaaaacc atatactaaa ttcaaaaaat aacaattaaa
    37441 ttggtcttat agactagttt aattgtttaa ctattcatac aattactcta tttttcttca
    37501 aaccttttaa tctaacattg ataaagatag attaattata tagacatctt tatttaaata
    37561 aaaaaatcta ggggtaaatc atattcttga ttttccctag atttagtaat aaaacttact
    37621 cttcctcaag ttcttttttc tcttccagta aaacacctaa ttcgtttgct tctaaaactt
    37681 gtgcctctgc aatatcaagt aactcttgtt gccattccac acatttatct ttgtaatcaa
    37741 aaggtagcgt tctgtcaact atgtacttat caatacagtc ctccgcactt ttaattattt
    37801 cttttctttc atcaataaat ttttctaatt ctactaaggc ttcttcataa gcttttctac
    37861 tcatataaat tccccctttg tacaattatt ctacattaaa atgatttttc ctcttttttg
    37921 tataaaattt tatttgtata taacttttcc atcaatatct tttatagttt gacatccagt
    37981 taatatcata gaactactta gctctgattg aagtttattt acataagttt ctacaccatc
    38041 agttgcacca ccaaatgaag cagtcacaaa aggtcttcct attaatactg catctgcacc
    38101 taaacctatc atttttagta cgtctaaacc agttctcact ccaccatctg caagtattgt
    38161 aactttacct ttaacagcat cagcaatttt tggtaaaact tcacatgctc ctggtgtaca
    38221 gtcaagcact cttcctccat gatttgatac aactattgca tacacacctg cttctactgc
    38281 cattaaagca tcttcaacag tcattatacc tttcaatata aatggtagtt tagtagactt
    38341 tactaactcc tttatttgtt taacattttt aggaagtact ggttttccat gtaatgataa
    38401 agttactaga ccacaggcat ctatatcaac tccaactgca aatgcaccag cttcttcagc
    38461 taatcttatc ttttttataa tattttcatt atcccaaggt ttaataaata caattccagc
    38521 tccattatac tttttgacta catctaaatt ttccattaaa aaagcatcta ctgccgtatc
    38581 accaaccatt gcataaatac cactattagc acatcctgca actactggtt ctatgtaatc
    38641 tctttcatta atttttccac ccatatttaa agtagttcct gttactggag ctgcaaatat
    38701 aggtgcactc attttctttc caaacatctc tatagatgta tcaggatttg atacatcatg
    38761 tattactctc atatttactt ttactttttc taaactcttg ctattttcta taaaagaaga
    38821 accacttcct ttacctccca tgccaggcac ttcacctgca caagcaaccc cattacaaac
    38881 cttacaaact ttacaacttc catttaaatt ttctctagca ctttttaata attcattata
    38941 ttccatcttt aatcccccat taactatagt aatttatatt atatacatta tatcatatta
    39001 tatttacagt atatttttca aaaaactttt tctgtggata ggagttatgc catatttttc
    39061 aatagcttca tagtgttctt tagttccata tcctttgtga gatttaaacc catattctgg
    39121 gtatactcta tcatattggt acattatact atccctagta actttagcaa gtatacttgc
    39181 tgctgctatt gatatagatt ttgaatctcc tttcacaatt ggattttgag atatgtcaat
    39241 acctggtatt gttgctgcat caactaataa ataatccggt gcttttttta aacaatttat
    39301 agcctttttc attgccatat atgtagcatt taatatatta aattcatcta tttcttcatt
    39361 atttactata cctattccat aatctagtgc ttcttctttt attacttcaa aaagttcatc
    39421 tctttttgcc tcactcagtt tcttagagtc atttacacct tctatttttg tatctttttt
    39481 aaatactaca acagaagcta caacaggtcc agcaagtggc cctcttcccg cctcatcaat
    39541 tcctccaata tacaaataac ctttatcata gccttcgttc tcaaatatat ttatagtttc
    39601 caatctttct tcttcttttc taatattatc cagctttttt gctagtttta tagctagacc
    39661 ttgtacagat tttctttcat caactcttaa cagttctata tattccatat atttttctac
    39721 ttctaaagtc tctattattt ctttaatctc cctcacactt ttatcctgca taccattccc
    39781 tcatctttcg tttttaaaaa tttaattttt aaatatatta aaatttttta attagagttt
    39841 aattgcatcc actatagcca cattttaaac atatactaca tccacctgta tgtgcaattc
    39901 cttcacttcc acattcaggg cacacaaatt tttcatcttc ttcaaaattt ttatttatta
    39961 tttctttggc tttttcatct ttattatctt tttctttttt attattttta taatattctt
    40021 ttttactatt ttctttttta tcttctttat tattttcttc ctttttttca tttattaaaa
    40081 ttccactcct tttacatcca tctctaaata ttgttactcc tttaagacca gcctcccatg
    40141 ccttaatata tatattgaaa acatcttcaa ctgtagtttc aaaaggtata tttattgtag
    40201 atgatataga agcatcaata tacttttgcc atactttttg catgtttatt ctttcttcat
    40261 atcctatatt catagcagta acaaaaaaat ctggtaaaca ttcttcatct gtaatacctt
    40321 tcttgtccat atactcttta acaattggag tatatacttt ataatacaca tcctcatcat
    40381 gcaagctttc agtttttctt atatatgaaa gattaaatat aggttctatt ccaccactga
    40441 tacctatcat tgtagatata gaacctgtag gaggtatggt taaaagttgt gaatttctaa
    40501 gcccatactt tttaaccatt tctttagtgt cttcatttag attttctata aaaaacttag
    40561 atttagaaat attttcatat ttatactcac taaatgttcc atattcttta gcaattaatg
    40621 ctgattgctt cacagcttca tttaacatag tcttaccaat taaatcacat agttctaaag
    40681 attcatcaga accatatctt attcccattt ttataagcat atcagctata cccattacac
    40741 ctaaacctat ctgtctatac ttatgtacac tatctctttg ttcttgtaat ggatgcaagt
    40801 tcaacccctc atctaagaca tcatttaaag ctactacagc ttctctaacg caagatttta
    40861 atttattaat atcaaaagta gcatgttcac caaatggttg tattataaac tctgacaagt
    40921 ttattgagcc aagtagacaa cttcctccac ttggaagtgg ttcttctgca caaggattta
    40981 ctcctgaaaa gcaaaagttc ttatcttcac tcataaaatt atatgttttt attttatccc
    41041 aaaacaatat acctggttct gcataatccc agttattttt cacaaattta ttaaataaat
    41101 cataagcatt tactatctta actatttttt ctccagtagt ttcaacttca aaagtacaat
    41161 tatataactt tttttccctt acagcttgca taaattcatc tgttaccctt atggaaatat
    41221 ttgctttagt aaccttctcc aaatctgttt ttatatctat aaactcttct atctccggat
    41281 gatttacatc catagaaatc ataagagctc ctcttctccc tctttgacca attaagccag
    41341 ttgtcatact gtaaagttcc ataaaagaga ctgctccagt cgtatgtttt gcagcattgt
    41401 taactttcgc tccttttggt cttagctttg aaatatcaat tccaactcct ccaccataac
    41461 taaaagttct agcaagtttt tttgcagtat caaatatatc ttctatgcta tcttttggtg
    41521 attctattac ataacaatta gaatatgtta ctttttttcc ttctttctgt aatcctctat
    41581 ttgctaaaat tcttccagca aatagaaatc ttttttgtct tattagtttt gatattcttg
    41641 aactattatt tgaaattctc tttatccatt catcaaaact ctcaccatta tgtctatact
    41701 tgttcttcca tattgatttt tgtaattcat caaactccca agctttagtc cttatttcag
    41761 agcgtctttc tctatataat atgtagtgtt ttgctatatc ttttctattt gattccataa
    41821 gtagtacttc aactatatct tgtatttctt ctacggataa gcatttttcc atagaattat
    41881 agtcattagc tatttttctt gatatatcat atgccaactc tctatctact ccaccttcac
    41941 tatttatact agctttatag acagcatctt caatcttact tttactaaaa agttcttttg
    42001 taccatctct ttttattatg tatttcattt ttaaacctcc aataaattag tattaaatta
    42061 atacacacat taactataac tctaaacaaa cttttttata tatttgtata ttttcatatt
    42121 aattatctaa cataatatat attatactat tttatat
//
LOCUS       DAMJWO010000031        41906 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.032, whole genome shotgun sequence.
ACCESSION   DAMJWO010000031 DAMJWO010000000
VERSION     DAMJWO010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41906
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.032"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..3184)
                     /locus_tag="PC366_001663"
     CDS             complement(<1..3184)
                     /locus_tag="PC366_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
                     /protein_id="HDF2577193.1"
                     /translation="MATVSGQIVFDRNRSATIDSGDSGIANIPVVLQDIATGVRLVVL
                     TDASGNYVFTNVPNGNYRIVEAFGTTGGVPTPGNFATAIVGPVPIAEMPPISSVTNPP
                     IGSTNLDGTTPNTLLITVAGSDIINQNILNGPVIYTPIENILDSCVSVSNINLITDAD
                     NGTFGFFPPGTPSNTGPEIEPYPNVTPDFTYVVPDPTKFTPLDGEYTVQNIMTNAMSN
                     VIGAWWRIADHTTGNETGRMMVVNGFNPGAVFFKSTVQVTPNTNYLFSTWILNLFKVT
                     GYPPPQLGVRIFDQNNNILYQATLGAQIPVNTNAPEWKEVGTVINSQNNNQLTVEFFS
                     EGESAIGNDYAIDDVSLREIAVPTFTPIKTSNTETANVGDIITYTVTLDNTCDSPLTN
                     VFFRDLIPNGLEFIPGTVTVDGVSVPGVDPNTGFPLPDIGGGIGVEVTFDVVVESIPN
                     PNPTNNIATIDYSYTPVEGGIPNDFSVDSNPVPVEVISADVEVTKLSEPTIVNPGEEL
                     IYTIKVVNNGPFPSENVVLTDDVPASIINPEYSLDGGVTFQPWTGSLNIGTLEVGETR
                     VIIIRGIVNPSTVGIITNTAVVSSTTADPNLNNNTSTIETEVNLLADILVMKTAEPNS
                     AVPGTLLRYTIQVENLGPANAENVILNDDIPASIINPEYSLDGGASFQPWNGSLNIGT
                     LNSGISLTVLIQGTVSLNSSEYIVNTATVSSTTPDPDLSNNISTIITPVNPQAGISII
                     KVADEDVAVPGEEFVYTIEIFNEGPSNATNVVLTDDIPDVILNPEYSLDGGATFQPWN
                     GSLNIGTVAPGQLIRIIIKGLVSSTATGDITNTAEVSADVPEPVTDSSTVTTPIVPSA
                     DIEVIKTSNMDTAVPGETFSYTITVINLGPSAAQSIVLTDDIPDVILNPEYSLDGGVT
                     FQPWNGNLSIGTLDAGEIRSIIIRGTVSQTAVGTIINTATISSPTPDPNPDNNTSTDE
                     TDISPLADISVIKGNEPVAIPGGRFIYGIEIANAGPSFAENVTLTDNIPASILNPEYS
                     IDNGVTFQPWNGSLNIGTLDAGEIRNIIIRG"
     gene            3975..4295
                     /locus_tag="PC366_001664"
     CDS             3975..4295
                     /locus_tag="PC366_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDF2577194.1"
                     /translation="MEKIMNFLKENSTFYFATVEDNKPRVRSFGFIMDYEGKLYFGIV
                     KYKTSYKQLLVNPNVEISTTSKVGKWIRIKGIEKTRYEFISSLFIYYLSKMIVFHNAK
                     NSLV"
     gene            complement(4244..4990)
                     /locus_tag="PC366_001665"
     CDS             complement(4244..4990)
                     /locus_tag="PC366_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDF2577195.1"
                     /translation="MLNSITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIVLIIYQ
                     IFKKKIKEKKVFYRVLKIIISIFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TTPSTTLKGRLDTALKYLKINDNCYVVVSGGKGSGEKITEAKAMKDYLIKNSIDKNRI
                     IEEDKSTNTYENFKYSKLKIEEHSQRKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIIFDR"
     gene            complement(5008..8445)
                     /locus_tag="PC366_001666"
     CDS             complement(5008..8445)
                     /locus_tag="PC366_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HDF2577196.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSVANMVSYFNTIDNSKIVPLLANISKESDFQRISIV
                     SPDGISHTSDGKIINVSKYQYFKKAIKGESNISEVVKSPIDGKDTFVIATPIFNKNNK
                     IIGVLYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYEDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIMLIIYIIYKNNKSQKDILKANKEISSITNSIPGG
                     VQKCTLGETCNINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEISKQL
                     YKNKTIELEYRIITKNGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENILGGIIITEFNDDFTIKYTNSGYLSMIGYTREQLENELKYKACNLVFY
                     EDRKKALESIQHQLNTKGIAVYQHRIRRRDGNIIWVSIKGRLIIDDDGIEKGIWILND
                     ITDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITKNV
                     PYSLVESGVIHKDFSDDFINMYENVINGAKKASCVVKMKLPDENYIWNKVTLTTIFDE
                     DGNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNESW
                     QKPFGIKPDNNYSEMVKTISNSIIHKDNKEVFLNTFLCKNLLSAYNKNITEIKLEYRR
                     MNQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKQKNEEIKLKLKAERDTLTGLYN
                     KGTTENLINDFLNSDEASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKHLKPI
                     FRKDDIVGRIGGDEFIVFLKNIQSFENTKKKAEKICDIFRNSYTENKKTYKISGTVGI
                     SFVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNNCIYQNELENNISDNNIKLANK
                     CEKSKPVLKEILDSIDNYIYIVNPNTYELLFVNNKVSRLDLEIKLGETCYKSLLKSER
                     PCNNCPLNGLEENKHSKFKIETNTFGKNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            complement(8478..9959)
                     /locus_tag="PC366_001667"
     CDS             complement(8478..9959)
                     /locus_tag="PC366_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2577197.1"
                     /translation="MKKNRLIIKNISIAFIVLFFFSVFTFFYIGNISRVLEYETNDIM
                     TVTITGWIILSFLFLCIIIYILYSKAKSQKTIEKVAYTDFVTGYSNWRKFELDVTNLL
                     KKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLNELTNINETFARVSAD
                     NFNILLTYNKKEDIINIIKKIIANNELVNLSFGIYEIKDKDLSVSVYSDRASLAKSSI
                     KNNSDVNFAFFNDKLREKLLLEDKIEKEMEYALESGQFVMYLQPKYNIKLDKFCGSEA
                     LVRWQYTEKEVIYPGDFIPIFEKNGFIRKIDMYILEQACKEIRSLFDKGISPLPISVN
                     FSRVDFLKKDFIENIVNICDRYKIPYSLIEIEITESSMFGDTDTLFNVSRNLQDIGFI
                     VAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVDDKDVDKSQIVIKSIVSLIKQLGIRV
                     VAEGIETRSQIEMLKKANCDIVQGYYFSKPLPIKEFEKLVYKI"
     gene            complement(10227..11066)
                     /locus_tag="PC366_001668"
     CDS             complement(10227..11066)
                     /locus_tag="PC366_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HDF2577198.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNNNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKKGIDFASEQVFNGANYIITPTGRNNIKNLELVENLI
                     LEIGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEGRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLVKEAIFNNDKNKLIEYFKKSSIRREA
                     LEK"
     gene            complement(11087..11620)
                     /locus_tag="PC366_001669"
     CDS             complement(11087..11620)
                     /locus_tag="PC366_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HDF2577199.1"
                     /translation="MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQI
                     SQKSIAELFSEGEDIFRNYETQACRELSISDKTVISTGGGVIKKDVNMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
                     NITNAVSENFKFDFKEK"
     gene            complement(11632..12441)
                     /gene="aroE"
                     /locus_tag="PC366_001670"
     CDS             complement(11632..12441)
                     /gene="aroE"
                     /locus_tag="PC366_001670"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDF2577200.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRIFEILNIESAYKNFEIPKEDIS
                     KLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
                     KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEF
                     LRIGNSMGKKTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLEFL"
     gene            complement(12488..13684)
                     /gene="pheA"
                     /locus_tag="PC366_001671"
     CDS             complement(12488..13684)
                     /gene="pheA"
                     /locus_tag="PC366_001671"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HDF2577201.1"
                     /translation="MEDLTRYRNEIDNIDKEIIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAIDNLDNKAYSQETVQFFNSIMEISRGLQKRLIDNDGEQKIEFSLDS
                     SNKKFDLSNVNKYKSLKDELNKKNILVGFPGKSGSFTEEALNKFFNKTISKKQFKEFE
                     DVFIALKNKEINYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLEDIKEIYSHPQGIGQCSEFLKQNSTWKLIPFNNTATSAELVRKLQDKTKAAIASKK
                     AASIYELEIISPCINDIANNYTRFVVISNQIHIEEESNKMSVVFSVEHEAGKLYKVLG
                     YFAENNINMTKIESRPMKNASWRYFFYIDFECSIYNSKVYDLLELIEHNTAYFKFMGV
                     YKNKTE"
     gene            complement(13687..14766)
                     /gene="aroC"
                     /locus_tag="PC366_001672"
     CDS             complement(13687..14766)
                     /gene="aroC"
                     /locus_tag="PC366_001672"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HDF2577202.1"
                     /translation="MSGIWGNNLKVSIFGESHGNAIGINIDGLPSGIELDLDKIDKEM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEIGAHIKKIK
                     NIEDMSFDYVNISKQQLSNLQTLELPLLDLSKEEAMKNTIIDAKNQRDSVGGIIECAV
                     VGINVGLGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKDKKDDILYIKGRHDP
                     CIVQRAIPVIEAVTAIGIFDLMKGR"
     gene            complement(14744..16057)
                     /gene="aroA"
                     /locus_tag="PC366_001673"
     CDS             complement(14744..16057)
                     /gene="aroA"
                     /locus_tag="PC366_001673"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HDF2577203.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSMAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLAFDGVKRFIGRGNLGKRPLDTYYEIFDRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTIKDFGVEI
                     INNNYKEFIIKGNQTYKARDYKVEGDYSQGAFYLSADAIGEDISILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNSTLIDASQCPDIIPVLSVVASLSIGRTTIIN
                     AGRLRIKECDRLHAINVELSKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFKMLGGRIDEWNMGK"
     gene            complement(16057..17121)
                     /locus_tag="PC366_001674"
     CDS             complement(16057..17121)
                     /locus_tag="PC366_001674"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HDF2577204.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTD
                     ENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            complement(17143..18156)
                     /gene="aroF"
                     /locus_tag="PC366_001675"
     CDS             complement(17143..18156)
                     /gene="aroF"
                     /locus_tag="PC366_001675"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HDF2577205.1"
                     /translation="MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKIVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            complement(18286..18441)
                     /locus_tag="PC366_001676"
     CDS             complement(18286..18441)
                     /locus_tag="PC366_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577206.1"
                     /translation="MKGILKELTAKLYSFFYFMFWGFYFSAGYFFYKNICTSFLVRPY
                     FSDFEHK"
     gene            complement(18618..19574)
                     /locus_tag="PC366_001677"
     CDS             complement(18618..19574)
                     /locus_tag="PC366_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HDF2577207.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYNFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFIGIIIFKIKKLL"
     gene            complement(19913..20611)
                     /locus_tag="PC366_001678"
     CDS             complement(19913..20611)
                     /locus_tag="PC366_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2577208.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTP
                     IEYNILSLLAKHHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
     gene            complement(20645..23347)
                     /locus_tag="PC366_001679"
     CDS             complement(20645..23347)
                     /locus_tag="PC366_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HDF2577209.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYAAGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALARK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEVITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKRFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     SSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETAAKREENTKMIYQIIKGFLRLSSKDDIVNKGIELLSLSLSRDVICYLNVDKHNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCIDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVENNKDKGSTFKFSLPKENE"
     gene            complement(23525..25342)
                     /gene="ftsH"
                     /locus_tag="PC366_001680"
     CDS             complement(23525..25342)
                     /gene="ftsH"
                     /locus_tag="PC366_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDF2577210.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLSILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALTEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKACH
                     KNAIEILENNIDKLHELANYLLEKETITGDEFMEILNLN"
     gene            complement(25373..25816)
                     /locus_tag="PC366_001681"
     CDS             complement(25373..25816)
                     /locus_tag="PC366_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2577211.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLSDFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQEHISSSIFDSYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            complement(26307..27197)
                     /gene="metA"
                     /locus_tag="PC366_001682"
     CDS             complement(26307..27197)
                     /gene="metA"
                     /locus_tag="PC366_001682"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HDF2577212.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKELKYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTGFNVSVEFIKISTRESKRSCNEYVKEFYKTFDEAKGE
                     YFDGFIITGAPVEQMEFEEVDYWNELEEIMDYSKRKTKSTLYICWAAQASLYKYYNVK
                     KLPLSQKCFGVFKHKVDKDSKIVDGFENEFFAPHSRHTTVNIEALKENKELSIVSHSK
                     EAGPYIITNSRDVFVMGHSEYDKYTLDKEYKRDINKGDKISIPQNYYINDDPSEEPTV
                     KWKKHSELLFRNWIKNYLIQ"
     gene            complement(27227..28492)
                     /locus_tag="PC366_001683"
     CDS             complement(27227..28492)
                     /locus_tag="PC366_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HDF2577213.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVSSVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENALKIARFLEKHENVDWINYPGLEDNKYYENAKKYLSRG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     regulatory      complement(28602..28704)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(28758..31415)
                     /locus_tag="PC366_001684"
     CDS             complement(28758..31415)
                     /locus_tag="PC366_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDF2577214.1"
                     /translation="MENHKQMPWHSRATHEILESLDSSEEGLTDTEAEKRLKENGLNE
                     LRKKPPRTTLQMLWSQITDAMVMILIGAAILSLIFGEFTEAFVILIIVTVNAVIGIVQ
                     EKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAMVPADLRLIET
                     SSLKIQEASLTGESVPSEKDADTILPKECVLGDRSNMAYTSSIVTYGRGVGVVVATGM
                     DTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGAFYQRPLLPMF
                     MIAISLAISIIPEGLPATATIVMALGVQRMAKRNALIRKLPAVETLGGATVICCDKTG
                     TLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCNDACINPDKTD
                     EILGDPTEGALIFMAKKFGIDQEALEEEYPRVFEQPFDSDRKCMTTVHNIDEKIIAYT
                     KGAVDEILDLCTKILTSKGERNITEVDKKNIHELCLNMSKDALRVLGFAKREISSIPK
                     EDSENIEYDLTFIGMVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHKVTATTIAHEL
                     GIWSEENTVISGDELDNFSDDELDEAVKNTTVFARVSPFDKLRIIQSLKRIGEVPAMT
                     GDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTIAYAIKEGRRVYRNIQ
                     KVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALALGVDPPSRNI
                     MKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQTMAFCVLAFS
                     QMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSAFLIAVILFVPVFRNAFNLTVLNNL
                     EWLITIVLAIMSVIQVEVGKIIKRKKRKK"
     gene            complement(31543..32286)
                     /gene="yaaA"
                     /locus_tag="PC366_001685"
     CDS             complement(31543..32286)
                     /gene="yaaA"
                     /locus_tag="PC366_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HDF2577215.1"
                     /translation="MIIMLSPAKNMKNIEVFDRDLSLPCFIDNTKEIVENIKTFGIED
                     FKNKMKINEKLAVLNKNRFESIKFDRLGNPAILTYDGIQYKNIEAENFTRKDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQTKLRVGEFKNLYEYWGNRIYKELIKEKTAIIN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGILKVESTQAKKARGMMTKYIVKNRIRD
                     IEELKKFNLEGYKYKENLSNNSEYIFVKE"
     gene            complement(32296..32760)
                     /gene="bcp"
                     /locus_tag="PC366_001686"
     CDS             complement(32296..32760)
                     /gene="bcp"
                     /locus_tag="PC366_001686"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HDF2577216.1"
                     /translation="MLSIGTKAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDIQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEKQE"
     gene            complement(33112..34809)
                     /gene="ade"
                     /locus_tag="PC366_001687"
     CDS             complement(33112..34809)
                     /gene="ade"
                     /locus_tag="PC366_001687"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HDF2577217.1"
                     /translation="MGNLKRQCDVSSGREKADIVLKNGTIINVFTEELITGDVAIVGD
                     TIVGIGDYKGNVEIDCSNKYISPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADP
                     HELVNVKGASAIDFLLESTKDIPLNVYIMVPSSVPATSFETNGVGKFSAKDMESYVNN
                     PRILGLGEVMCFNDVINSENEILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDH
                     ECITFDEVYEKLRAGLKILIREGSAAKNLKSIVSGMLKHNLPIEEFMFCTDDKHLDDI
                     EKQGHIRWNIKCAIDLGMEPVRAIKVATYNSAKAYGLRKIGAIGAGYKADIVVLNDLD
                     KMEVDSVYKDGNLVNEEMFSNYNYEIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEI
                     VPYQILTNKVYESLPCADGYFVPNKEYSKLCVVERHRMTGNVAIASLKGFGIKNGAIA
                     TTVAHDSHNIIVAGDNDDDILVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTFT
                     AEEVQEITDNMLEIARKMGVPEYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
     gene            complement(35115..36269)
                     /locus_tag="PC366_001688"
     CDS             complement(35115..36269)
                     /locus_tag="PC366_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic efflux protein"
                     /protein_id="HDF2577218.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDISKNNPKENKEQHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKFYIGIIVIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMIITTIPAILVGMIVYAFLG"
     gene            complement(36514..37353)
                     /locus_tag="PC366_001689"
     CDS             complement(36514..37353)
                     /locus_tag="PC366_001689"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HDF2577219.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKNDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKDKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFNNSKKYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKEVDCMIVIGGK
                     HSSNTQKLVKVCEDLVPTFAIETKDELDVNTLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            complement(37366..37962)
                     /locus_tag="PC366_001690"
     CDS             complement(37366..37962)
                     /locus_tag="PC366_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HDF2577220.1"
                     /translation="MNFYRFVINIFKGFSKIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAIENREIAAIAKKELFKVKPLGFILKKLHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLSNDDHERISQEILEVIKQNYFKYSK"
     gene            complement(38013..38663)
                     /locus_tag="PC366_001691"
     CDS             complement(38013..38663)
                     /locus_tag="PC366_001691"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HDF2577221.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGVDVNNEKEVIQIAENSDIDFKDNNIYLDKEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVEVQRKIGMKSSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKG
                     YNTTLEEVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVVSKINL"
     gene            complement(38709..39962)
                     /locus_tag="PC366_001692"
     CDS             complement(38709..39962)
                     /locus_tag="PC366_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2577222.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNREIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEKENDHK
                     VYTKNDKSIEVIEVLNKDLLNHNVKIMYNKKVIDIITEEIALKDDSNKDKSKYLIKGI
                     ILDNGDKILGDKVIISTGGVSYSKTGSDGSMYKILKKHGHTLNKLYPALVPLTIEEKW
                     IKDLQGISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLSTDEISSIIRAFPNKNVLNNLKQILPQNFLREIFSLLSLVDKKASDLSK
                     ADEIRIIEYIKNMKLTCNGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            complement(39986..40627)
                     /locus_tag="PC366_001693"
     CDS             complement(39986..40627)
                     /locus_tag="PC366_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDF2577223.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILGDKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIVKMNDTSHIKNHVKINNSALE"
     gene            complement(40829..41242)
                     /locus_tag="PC366_001694"
     CDS             complement(40829..41242)
                     /locus_tag="PC366_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HDF2577224.1"
                     /translation="MIELKNNLGISERKLKYPCIYKHFKGKYYATMGLSKAIDDIENI
                     CEIYGKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNLYHKKEEDTNDLVLYKTLYD
                     DTGIFARPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            complement(41393..41734)
                     /locus_tag="PC366_001695"
     CDS             complement(41393..41734)
                     /locus_tag="PC366_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HDF2577225.1"
                     /translation="MKEENFINVEYEDKRFSINSKEVLYIEKQEYEVKIYTESGNYEV
                     GENAPCIRKLLKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
BASE COUNT        13231 a         7233 c         4504 g        16938 t
ORIGIN      
        1 ttccccttat tatgatattt cttatctctc cagcatctaa agtacctata ttaaggcttc
       61 cattccatgg ttggaaagtc actccattat ctattgagta ctctggattt aaaatagaag
      121 ctggtatatt atctgttaaa gttacgttct ctgcaaaaga tggtcctgca tttgcaattt
      181 caattccata aataaatctt ccccctggta tagcaactgg ttcgttgcct tttatcacag
      241 aaatatctgc taatggactt atatctgttt catctgttga agtattatta tctggatttg
      301 ggtcaggtgt aggtgaactt attgttgctg tatttataat tgtacctact gctgtctggc
      361 tcactgttcc tcttattata atacttctta tttctccagc atccaaagtg cctatactaa
      421 gatttccatt ccatggttgg aaagttactc ctccatccaa tgaatactct ggatttaaaa
      481 taacatctgg tatatcatct gtcaaaacga tactttgtgc agcagatggt cctaaattta
      541 taactgttat agtataacta aaagtttctc ctggaactgc tgtatccata ttgctagttt
      601 ttattacttc tatatctgct gatggaacta taggagttgt cactgttgat gaatccgtaa
      661 ctggttctgg tacatctgca cttacttctg ctgtattagt aatatctcct gtagcagttg
      721 aacttactaa tccctttatg ataattctta ttaattgccc tggtgcaact gtacctatat
      781 taagacttcc attccatggt tggaaagttg ctcctccatc caatgaatat tctggattta
      841 aaataacatc tggtatatca tctgttaaaa ctacattcgt agcattagat ggtccttcat
      901 taaaaatttc aattgtatat acaaattctt ctcctggaac agctacatcc tcgtcagcta
      961 cttttataat agaaatacct gcttgtgggt taactggtgt aataatggta gatatattgt
     1021 tgcttaaatc tgggtcaggt gtagttgaag aaactgttgc tgtatttact atatattctg
     1081 aagaatttaa actaactgtt ccttgaatta aaactgttaa tgaaattcca gagtttaaag
     1141 ttcctatatt aagacttcca ttccatggtt gaaaacttgc tcctccatcc aatgaatatt
     1201 ctggatttat aatagaggct ggaatatcat catttaatat tacattttca gcatttgctg
     1261 gtcctaagtt ttctacttga atagtatatc tcaataaagt acctggaaca gctgaattag
     1321 gttctgctgt tttcattact aaaatatctg ctaataaatt cacttctgtc tctattgtag
     1381 atgtattatt attaaggttt gggtctgctg tagttgaaga tactacagct gtatttgtta
     1441 taattcctac tgttgatgga tttacaatac ccctaattat aataactctt gtctctccta
     1501 cttctaatgt ccctatattt aaacttccag tccatggttg aaaagttact cctccatcta
     1561 atgaatactc tggatttata atagaagctg gtacatcatc tgttaaaacc acattctcag
     1621 atgggaatgg tccattattt actactttta tagtgtatat taattcctct cctggattca
     1681 ctatagtagg ttcagataat tttgtaactt caacatctgc tgagattact tcaacaggaa
     1741 ctggattaga atctactgaa aaatcatttg gtataccgcc ttctacaggt gtataggagt
     1801 aatctatagt agctatatta ttagtaggat ttgggttagg aatactttca accacaacat
     1861 caaaagttac ttcaacccct attcctcctc caatatctgg aagtggaaaa cctgtattag
     1921 ggtctactcc tggtacagat actccatcaa ccgttacagt tccaggtata aactctaaac
     1981 catttggaat taaatcccta aaaaatacat tagttaaagg gctatcacaa gtattatcta
     2041 atgtaactgt atatgtgatt atatcaccta cattagcagt ttctgtgtta cttgttttta
     2101 ttggagtaaa ggttggaaca gctatttctc ttaaagaaac atcatctata gcatagtcat
     2161 ttccaatggc gctttctcct tcactaaaaa attctactgt aagttgatta ttattttgag
     2221 aattaatcac agtacctact tctttccatt ctggtgcgtt tgtattaact ggaatttgag
     2281 ctcctaatgt tgcttgatat agtatattat tattttggtc aaatattctt acacctagct
     2341 gtggtggtgg atatcctgtt accttaaaaa ggtttaaaat ccaagtgcta aataaataat
     2401 tagtgttagg tgtaacttgt actgttgatt taaaaaatac agctccagga ttaaaaccat
     2461 ttaccaccat cattcttcct gtttcatttc ctgtagtatg gtcagcaata cgccaccaag
     2521 ctcctataac attactcatt gcatttgtca taatattttg tactgtatat tctccatcta
     2581 aaggtgtaaa cttagttggg tctggtacaa catacgtaaa atctggcgtc acatttgggt
     2641 aaggttctat ttcaggtcct gtattacttg gtgtacctgg tggaaaaaaa ccgaatgttc
     2701 cgttatctgc atctgtaata aggtttatat tagatacaga cacgcaagaa tccaatatat
     2761 tctctatagg tgtataaatc acaggcccat ttaatatatt ttgatttatt atatctgaac
     2821 ctgctactgt tattaatagt gtgttaggtg ttgtaccatc taagtttgtt gaaccaatag
     2881 gaggatttgt cacagaacta ataggtggca tttctgcaat tggaactgga cctactatcg
     2941 ctgttgcaaa attccctggt gttggtactc ctcctgtagt tccaaaagct tctacaattc
     3001 tatagttacc atttggaaca ttagtaaaaa cataatttcc tgatgcatct gtgagaacca
     3061 caagtctaac tccagttgct atatcttgta atacaactgg tatattggct attcctgagt
     3121 ccccagaatc aatggtagca cttctatttc tatcaaaaac tatttgtcct gatactgttg
     3181 ccatattatc actcctttgt gattacaaaa tttgtgttca taatatatta ttctttgaaa
     3241 ctcttttatg tgacatttta agcctataag tgcgcttttt ttctataaca tctaatatgt
     3301 atttttttta tttgcaatat caattttttt atattttatt gtatatgtta aaaaatatct
     3361 tatgtcataa gttaaaaact atcaaacaat agtaaatggc ataaaaggta ttattttatg
     3421 ccatttttca ataatcaagt attttcaatg tatttataat aacaaaatta caatttgtca
     3481 gtgaaatgtc agtgattttt ttgttatttt ttactctttt taatttgaga agattaagaa
     3541 tatgctttta tattataaat catcaaacaa aatatcgtaa aatttaaact taattacttg
     3601 agatattcag agatataatt ttttgtattt tatttttatc taattgagtt tagagggtct
     3661 atttttctcg aaaataacaa gcttttatat tgctttttaa atgggtttaa tttttttcgg
     3721 tgatagtttg tacctttcta atcaaatcaa gcttaaaatc tacttaaata cttaatctgg
     3781 cactttaatc taaaatcaat aattttagtt tactttattt ttattatgta aactgaaatg
     3841 tttttctgaa ttttatatat aattttgaat aatcaatata atattgtaat tgtttttata
     3901 tcaatttata ttagtattat aaatatttta tttatattca ttatattagt ataagataca
     3961 aagaggattt aatcatggaa aaaataatga attttttaaa agaaaactca acattctatt
     4021 ttgctacagt tgaagataat aaaccaagag taagatcatt cggatttata atggattatg
     4081 aaggaaaatt atattttgga atcgtaaaat ataaaacttc ttataagcaa ttacttgtaa
     4141 atcccaatgt tgaaatttct acaacaagta aagttggaaa atggattaga attaagggaa
     4201 tagaaaagac tagatatgag tttatatcta gtctttttat ttattatcta tcaaaaatga
     4261 ttgttttcca taatgcaaaa aattctcttg tatagtaagt tggtacaaat gaaagttttg
     4321 atttactagc ataaaaagac gtatttttat atccatttct atatgctaat attttacttc
     4381 tgagaacatg aaaatctgtt gttactattt ttacttttaa atcacttagt tttctttgac
     4441 tatgttcttc tatcttcaat tttgaatatt taaaattctc ataagtattc gtggatttat
     4501 cctcttctat tatcctattt ttatctatac tattttttat aagataatct ttcatagctt
     4561 ttgcctcagt tattttttct ccacttcctt taccaccaga tactaccaca taacaattat
     4621 cattaatttt taggtatttc aatgcagtgt ctaacctacc cttcagggtt gtacttggtg
     4681 tagtcttttt tacagaagct cctaaaatta agagataatc actttttgat tctaaactat
     4741 ttttaggata aaaaataatt aaactctcag taactacaaa tactattaaa aaaatgctga
     4801 ttattatttt taacacccta taaaaaacct tcttttcttt aatttttttc ttaaatattt
     4861 gatagataat tagtacaatt cctacaacta agaaaatctc actaaatgaa attcctccaa
     4921 aaactatttt gagataaaaa tagtaaattg taaatattat accaagtatc aaagttatac
     4981 tatttaacat atcttcatag tcctttttta tttatttttg tataaagaag aatctataca
     5041 ctctataaga cagttgtatt ctccatctat gcaattaatc caacttgcta tactgatatt
     5101 tttaccaaat gtatttgtct ctattttgaa ttttgaatgc ttattttctt ctaatccgtt
     5161 aagagggcaa ttattacatg gtctctcaga ttttaatagt gatttataac aggtttctcc
     5221 taattttatc tctaaatcca aacgagacac cttattattg acaaaaagaa gttcataagt
     5281 atttggattc actatataaa tataattatc aatagaatca agaatttctt taagtactgg
     5341 tttggatttc tcacatttat ttgctaattt tatattatta tcacttatat tattttcaag
     5401 ttcattttgg tagatacaat tattataaag tgcatactta tcttttcctt tgctctttgc
     5461 ataataaagt gctatgtctg cttttttata aagttcttca aatacagttc catgttctgg
     5521 tacaaatgaa attccaactg ttccagatat tttatatgtc tttttatttt ccgtataaga
     5581 atttctaaat atatcgcata ttttttctgc tttctttttg gtattctcaa aagactgaat
     5641 attttttaag aatactataa attcatctcc accaattcga cctactatat catcttttct
     5701 aaatataggt tttaggtgtt tagaaacttc aaataatact ttatctccaa atacatgtcc
     5761 taaattatca tttacagatt taaaattatc tatatcaaca attaaaaatg catgcattcc
     5821 taagcttgct tcgtcagagt tcaagaaatc attaatcaaa ttttctgtag tacctttatt
     5881 atataatcct gtaagagtat ctctttcagc ttttaatttt aatttaattt cttcattttt
     5941 ttgcttgtca atatctttaa cataagcaag tgcttttata tcattcgtaa tagaatcttt
     6001 tattaagtgc attgtgcaaa tgacccaaat cattttattt tcttgattca ttcttcgata
     6061 ttctaatttt atttcagtta tatttttgtt atatgcagat aataaatttt tacacaaaaa
     6121 tgtatttaaa aacacctctt tattgtcttt gtgaataata ctgtttgata tagtttttac
     6181 catttcagaa taattattgt caggcttaat tccaaatggt ttttgccaac tttcatttcc
     6241 tttgataaaa gtatcttttg atacatttat ttcataggtt atcattgctt ccgacaatat
     6301 agctgaatga tacttacctt cttgattata tcttatctct gcttcctttt gtttgcttat
     6361 atcttcctgt ataccaattg ctcttacagg attaccatct tcatcaaaaa tagtagtcaa
     6421 ggtaacttta ttccatatat aattttcatc tggaagtttc atcttaacta cacaacttgc
     6481 tttttttgct ccatttatta cattttcata catgtttata aaatcatcac taaaatcttt
     6541 atgaataact cctgattcta ctagagaata tggaacgttt ttagtaattt tataaatatt
     6601 atatttatca agctctttac tagtatttaa aagtgacttt gtttttatat catactcaaa
     6661 tatagtattt gatgtttgct ttaatgcaat tctaaatctt tcttcattta ttttaagttt
     6721 ttgttctgca ttttttaaat ctgttatgtc atttagaatc caaatacctt tttcaatacc
     6781 atcatcatca ataataagcc ttccttttat agaaacccag ataatattac catctcttct
     6841 tcttattcta tgttgatata cagctattcc ttttgtgttt aattgatgtt gtatactttc
     6901 aagagccttc tttctatctt cataaaaaac aagattacaa gctttgtatt taagttcatt
     6961 ttctaattgt tcacgtgtat atccaatcat tgaaagataa ccagagttag tgtattttat
     7021 agtaaaatca tcattaaatt ctgttataat tataccacct aaaatatttt ctgatatcat
     7081 ttcaagttct agattttttt gttccatctc ttgttctaat tgttttgttc tagtaatatc
     7141 tacagttaca caacaaaaat attcttttcc atcaggttct gttataagtt ctcctttatc
     7201 taaaacccat actgtattac cattttttgt tataatccta tattctaatt caatagtttt
     7261 atttttgtaa agttgtttag aaatttcttt ttttattctt tcaacatcat ctttatgtat
     7321 taaactataa aaatcattat taaacaatgt ttttatttct tctcttgtat aaccaaacaa
     7381 ctctataaat ccatcactta aaaaattaat attgcatgtt tcacccaggg tacacttttg
     7441 tactcctcca ggaatgctat ttgtaataga tgagatttct ttgttagctt ttagtatatc
     7501 tttctgagat ttattgtttt tataaataat atatattata agcataataa acaataagaa
     7561 tactttgaaa ataagagaaa atgctaattg atttatttta tcaatgtttc ttcttacagt
     7621 atattgtggt atcacagaaa ttacatacca gtcatttaca ccaatgggtg tataagtagc
     7681 ataacgattt tctcctttgt attcatatga ggtaaagcca ctcttgttat tttttgtatc
     7741 ttcatatatt tttttatagc tataaccatc atcaaaagaa gcttttttaa atatatcata
     7801 tatgttacta cttgacttaa tcagtttgtt tgtatgtgaa gattttaaaa caaattgacc
     7861 actagattca aatatatcta tgtacccttc actattaaaa cttgttatat ctataaattc
     7921 agctaattta tcattgtagt aagaaccgta taaaacacca attattttgt tattcttatt
     7981 aaatatagga gtagctataa caaaagtatc ttttccatca attggagatt tcacaacttc
     8041 agatatattg ctttctcctt taatagcttt cttaaaatac tgatattttg acacattgat
     8101 aattttgcca tcgctggtat gacttattcc atcaggagat acaatagaga ttctttgaaa
     8161 gtcagattct tttgatatgt tagctaataa tggaactatt tttgagttat ctatagtatt
     8221 aaaataagaa accatatttg ccacactttt aataaaggat agagaactat ctaattttat
     8281 ttttatagca ttggaacttt gtagggatat ttcccttaaa ttaattttac tattttcttc
     8341 ttcctggaca ttagttttaa atgcaaaatc agaaaaagaa attattgtaa ataaaaatat
     8401 taaaacaata ctcagtacat tttttaacga ttttgctctt atcacttaat caccacctcc
     8461 catttaagac tcgctgacta tattttatag actaattttt caaattcttt aattggtaat
     8521 ggttttgaaa aataatatcc ttgaacaata tcacaatttg ctttttttaa catttctatt
     8581 tgacttcttg tttcaattcc ttcagcaaca acccttattc ctaattgctt aatgagagaa
     8641 actatgcttt ttataacaat ttgactctta tcaacatctt tatcatcaac aaaaaatcct
     8701 ctatctaatt ttattacatt taatggtata tttttaagca tatttacaga agaatatccc
     8761 gagccaaaat catccattgc aactataaaa ccaatatcct gtaggtttct actaacatta
     8821 aatagagtat cagtatctcc aaacatacta gattcagtaa tttcaatttc tattaaacta
     8881 tatggtattt tatatctatc acatatattt actatgtttt caataaaatc tttttttaaa
     8941 aaatcaactc ttgagaagtt tacagatata ggtaaaggtg aaattccttt atcaaataaa
     9001 gaccggattt ctttacaagc ttgttctaat atgtacatat caatttttct aataaatcca
     9061 tttttttcaa atataggaat aaaatcacct ggatatatga cttctttttc tgtatattgc
     9121 catctgacta gggcttcact tccacaaaat ttatctaatt taatattata ttttggttgt
     9181 aaatacatta cgaattgccc actttcaaga gcatattcca tttctttttc tatcttatct
     9241 tcaagtaata atttctctct taatttatca ttaaaaaatg caaaatttac atcactatta
     9301 ttttttattg atgattttgc aagtgaagct ctatcactat atacacttac agataaatcc
     9361 ttatctttga tttcataaat tccaaaagat aagtttacaa gttcattatt tgctataatt
     9421 tttttaataa tatttattat atcctctttt ttgttatatg ttaataatat attaaaatta
     9481 tcagcactta cacgagcaaa agtttcattg atattagtca attcatttaa agtatctgca
     9541 atatctttta atattaaatt gcccttttta tgtccatata tatcattaat tgctttaaat
     9601 ttatcaatat cgaatatgac cattgcatat ttattatttt gtgatgtttt ctttaataaa
     9661 tttgtaacat ctaattcaaa ctttctccag ttggaataac ctgttacaaa atccgtatat
     9721 gctacttttt ctatagtttt ttgactcttt gcttttgaat ataatatgta aattataata
     9781 cataaaaata aaaatgaaag tataatccat ccagtaattg taactgtcat tatgtcattt
     9841 gtttcatatt ctaatactct actaatatta cctatataaa agaatgtaaa tacactaaaa
     9901 aagaatagta ctataaatgc tattgatata ttctttatta ttaatctatt ttttttcaaa
     9961 tagctacacc tcactctctt tagcaattat aatataattg attcacttta ttttactatt
    10021 aataagtatt ttttacaatt aagttttata aattgttaat aaagagcatt taaataaata
    10081 tcattatcat ttaaaagata acaatagtta agggtacaaa tatatcaata gcatatttaa
    10141 ttatattgaa tccatattta ttaatacaat taaatacact atcgcttaca tttataccca
    10201 tctatatata gcttaaatat taatatttat ttttctaaag cttctcttct tattgatgat
    10261 tttttaaaat actctatcaa tttattttta tcattgttaa atatagcttc ttttactaaa
    10321 tttacttctg attcaaagtt ttctataact tttagtaaat tatctctatt tcctaaaaaa
    10381 agttcactcc ataagtcttc attcatattt gcaattctag ttaaatctct ataactatct
    10441 ccaataaatt tacctgtatc tctaccttct tcatcactat ttataagagc aactgccata
    10501 acatgaggta actgagaagt aaaagctata atctcatcat gtttttgtga agttaacttt
    10561 tttactcttt taaatccaat ctctaaaatt aaattttcaa ctaactctaa attttttatg
    10621 ttgtttctgc cagttggagt aattatataa tttgcgccat taaaaacttg ttcacttgca
    10681 aaatcaatac cctttttttc cctacctgcc attggatgtc caaatataaa atctatatca
    10741 tctggaataa tttgcaacac atcattgata agtgtttctt ttattcctgt agtatcagta
    10801 attatagtcc cttttttaaa aaagttttta ttattattta gaaaatctac aactaatcta
    10861 ggatatatag atagtataat taaatcagct tttttaaata actctttacc tgtagtacat
    10921 ccttttttta tgatttttgc tttttctgct ttttttaaag tttctaaatc tacatctact
    10981 ccaaatacat tttcatatcc agcttttttt aatgctttag caaaagagcc tcctataact
    11041 cctagtccta caataacaat attcattatt tttatttccc cctagattat ttttctttaa
    11101 agtcaaattt aaaattttca ctgactgcat ttgtaatatt atatacagca ttatttaatg
    11161 atttatcatt taaaatctct atatctgaaa attttttata aagatttatt ctctcattat
    11221 aaagattata caatctatct tttccgtttt ttaataatgg tcttgaatta atatttatat
    11281 cttccaaaat cttttgtata ggtctatcaa taaaaattat tatacctgtt tcttttagta
    11341 tttccatatt aacatccttt tttattacac ctccacctgt agatatcact gttttatcac
    11401 ttatagaaag ttctctacat gcttgagtct catagttcct aaagatatct tctccttctg
    11461 aaaacaactc tgctatactt ttttgagata tttgaattat ataatcatcc atatcacaga
    11521 aactacaatt atattctttg gccaaaagtt taccaattgt agtttttcca ctacctggca
    11581 tacctattaa tatcaatttt tcttttgttt tatttatcat gacaatctcc cttacaaaaa
    11641 ttctaatttt agttcattat atataacatc taaaatacta ttatctattt tagtatcttg
    11701 ccaaatttcc tgagatttta ttgcttgccc taccagcata tataatccat cacaagtttt
    11761 tttacccata ctattaccaa ttcttaaaaa ctctgtttct ccaggattgt aaattaaatc
    11821 tattaatata tcaaaatttt gtataataga ttttgacact ggtgaaattc ctacattagg
    11881 gtacatacct actggtgtag catttaatat tatatctcct tttatatgtt taagttcttc
    11941 ataatctatt aatatagctt tactatttaa taatttttta tcatcctttt ttctagttga
    12001 aacataaagc ttttctatac cagaatcaat aaaatatgta agagcagctt tagaagcacc
    12061 tccagttcct aatataactg ctacttttcc ttgaacatca atattagcca ttttaaacat
    12121 actatcaaga ccaaagtaat ctgtattgta accatataac atattttctc tgagtaaaat
    12181 tgtattaact gctcctatac gttttgcctc tggtgatata aaatcaagat atttcataat
    12241 acgctcctta tatggtacag taacatttac tccttgtatt cctaataatt ttatagcacc
    12301 gtctagctta gatatatctt cttttggaat ttcaaagttt ttataagcac tttcaatatt
    12361 caatatctcg aatattctct tgtggatttg aggtgaaaca ctgtgagaga gtttttcacc
    12421 tactagaccg aaaaaattca tacttacacc tcctaataat tataaattaa ataaaaattt
    12481 atattatcta ttcagtttta tttttatata ctcccataaa tttaaaatat gctgtattat
    12541 gttctatcaa ttctaataag tcgtacactt tagaattgta tatagaacac tcaaaatcta
    12601 tataaaagaa atatctccat gaggcatttt tcataggtct tgactctatt tttgtcatat
    12661 ttatattatt ttcagcaaag tatccaagta ctttataaag ttttcctgct tcatgttcaa
    12721 cagaaaatac tacactcatt ttgtttgatt cttcttcaat gtgtatttga ttactgatta
    12781 ctacaaatct tgtatagttg tttgcaatat catttataca aggacttatt atttctaatt
    12841 cataaatact tgcagctttt ttgcttgcaa ttgctgcttt tgttttatct tgaagttttc
    12901 ttacaagttc tgcacttgtt gctgtgttat taaatggtat caatttccat gtactatttt
    12961 gttttaaaaa ttcactacat tgtcctatac cttgtggatg agaatatatt tcttttatat
    13021 cttcaagttt tgtgtctttt atccctatta aattttggtc tatttttata cattcttctc
    13081 caactatata aaaaccgtac tttctcaaaa ggtcataagt ttcagagata gctcctgtag
    13141 atgaattttc tatggggatt attccatagt ttatttcttt atttttaagt gctatgaaaa
    13201 catcttcaaa ttctttaaat tgtttttttg atattgtttt gttgaagaat ttatttagtg
    13261 cttcttctgt aaatgaacct gattttcctg gaaatcctac taggatattt tttttattta
    13321 attcatcttt taaagactta tatttattta catttgacaa atcaaatttc ttatttgatg
    13381 aatctaaact aaactcgatt ttctgctcac catcattatc tatcaatctt ttttgtaatc
    13441 ctctactaat ttccattata gaattaaaaa actgtaccgt ttcttgtgag tatgctttat
    13501 tatctaaatt atctatggct ctacttagta ctttttcttc tctatctttt tgaagtatag
    13561 tagtgttatt tttcatttta tgtctggcaa tttcaagaac tgtattcatt ctcttttcaa
    13621 ataattgaat aatctcttta tctatattgt caatctcatt tctatatctc gttaaatcct
    13681 ccattattat cgtcctttca tcaaatcaaa aattccaatg gctgttactg cttctattac
    13741 aggtatagcc ctttgaacta tacaagggtc atgtctgcct ttaatatata aaatatcgtc
    13801 ctttttatct tttatattaa ctgtgttttg ttgtctgcta attgaaggag ttggcttaat
    13861 tgccactttg aaaattattg gcattccagt agtaatccct cctataatcc ctccattgtt
    13921 atttgttttg ctcttaactt gatttccttc ataatacatt tcatcattac tttgagagcc
    13981 atacatatct gcaagttcaa aacctaaacc aaactctaca ccttttacgg caggaacaga
    14041 aaacaataaa tgtgataaag tagattcaac agagtcaaaa aatggatttc caagccctac
    14101 attaatacct actactgcac actcaattat accaccaact gaatctcttt gattttttgc
    14161 atctataatc gtatttttca tggcttcttc ctttgataaa tcaagtaaag gtagttccaa
    14221 agtttgcaaa tttgataact gttgttttga aatatttaca taatcaaaac tcatatcttc
    14281 tatattttta atttttttta tgtgtgctcc tatctctatt cctttttgtg ataaaatttg
    14341 tttacatata gccccacaaa atactaatgg agctgttatc ctacctgaaa aatgacctcc
    14401 ccctctatag tcattaaatc cagaatatct cacattacct gtgaaatctg catgtcctgg
    14461 tctcattaaa tttttaagct ctccataatc ttttgaacga gtatcactat ttcttatgat
    14521 tgcacataat ggcgttcctg tagttcttcc attaaaatat ccacttagaa tttctggtat
    14581 atcactttca tttcttgaag tagatataga attttttcca ggtgctcttc tcttcatttc
    14641 tttatcaatc ttatcaaggt caagttcaat ccccgaagga agaccatcta tatttatacc
    14701 tatagcattt ccatgagatt ctccaaaaat tgatactttt aaattatttc cccatattcc
    14761 actcatcaat tcgacctcct aacatcttaa aatctttaaa aaaatgtgga taagattttg
    14821 atacacactc aaaatctttt aatattattg gtttatcaca tctacaagaa gcaattgcaa
    14881 gtgtcatagc aattctatgg tctttgtgac tccacacctc tactccacca tttaacttgc
    14941 ttactccttc gattatcaaa ctatcctctt tctcctctat atttgctcca agtttactta
    15001 actcaacatt tattgcatga agtctatcac attctttaat tctaagccta ccagcattaa
    15061 ttattgtagt cctccctata cttaaggatg ctactacaga taatacaggt attatatctg
    15121 ggcattgaga tgcatctatc aaagtactat ttaaaccatt tgttattcct tttattttgt
    15181 tgccttctct taatatttcc attcccatcc tagataaaat ttcaactact tcactatccc
    15241 cttgaagaga atcttcttta aggtctaata tgctaatatc ttctcctata gcatctgctg
    15301 ataaataaaa tgctccttga gaataatctc cttctacttt ataatctctc gctttatacg
    15361 tttgatttcc ttttataata aattctttat agttattgtt tataatttct accccaaaat
    15421 cttttatcgt tgaaagagtt aaatctaaat atcctttaga ttctagctca gtagtaatta
    15481 ttatctttga atcactctct agtgtaggca atataaacaa tagacctgtg ataaactgag
    15541 aacttatatt tccttttact ctaaattcat ctggtttaag cttacctgat ataatcaaat
    15601 ctaactgatt ttctttgtaa ctatatttta tattctgtct gtcaaatatc tcataataag
    15661 tatcaagtgg tctttttcca agattacctc tacctataaa cctttttaca ccatcaaatg
    15721 ctaaagatat aggtactaaa aatcttaatg tagagcctga ttcattacaa tctattgtca
    15781 atttaggttg attcaactga ttctctctat ttaaaatacc ttctttagaa aaaattcccg
    15841 aaatttctaa aatatcttct ttcttttcta taatagctcc taatgatgtc attgctctta
    15901 tagtagctat tatatcatca gaaaaatcta tattagaaat tctacttttt ccattgctta
    15961 gagatgaaca aataactgcc ctatgtgcca tactttttga tggtggtatt tttacatctc
    16021 cagataattt acttggatat atttttagac ttcccattat cttacctcct gaaaaaattt
    16081 agaagtagta ttatatataa tactctctcc aatatctttt aaaagtatta tttttaatgt
    16141 atcacctaga ttttttttat caagagatat agcatctact atagatttat tatctcttaa
    16201 ttcaatctca taaggcaaat tataattcat taaaattgat tttataagtt ctgatgtacc
    16261 tttttttgta attcctatct tttcactttc taaagttatc ttatacattc ctatggcaac
    16321 agcttctcca tgggtataac ccgtaaaatt gtagtatttc tcaatagcat gacctaatgt
    16381 atggccaaag tttagaagca ttctatctcc aaagtctttt tcatcagctt caactacagt
    16441 ttttttaata aagcaacatt tatgtataat gtattctata tgttgcatta cttcttctct
    16501 attttttaaa cttaaaagtt tattgaaaaa agttttgtct tttatacatc catattttat
    16561 aacttctgcc attccatctc tatagaattt ttctggaagt gataataata catttgggtc
    16621 gataaacaca gcttttggtt ggtaaaagct tcccactaaa tttttgcctc tctcaaggtc
    16681 aactccaact tttccaccta cagaactatc aacttgtgct aataaagatg ttggaatttg
    16741 aataaaactt atacctctta aaaaagttgc tgctgcaaat ccacctaaat cacctattac
    16801 ccctcctcct aaagtaataa tcaaatcttt tctagttaac ttaaagtcaa gtaaactatc
    16861 gtatatttta ggaagagtat taaatgattt tgtttcttca ccagatttta atattaaaga
    16921 tttaatttca aatccagatt cacttaaatt attttttact ttatccaagt ataattttgc
    16981 tatattttca tcagttacaa taaaaatctt atttccaaaa tatatttttt ttatttcttc
    17041 tcctatattc tttagtatat tttttttaat aaatatattg tagctatttt cttttaaatt
    17101 tactaatagt ttttcttcca cgtttaacca tccttttata gattatattt ctctaccaac
    17161 tgctgatgcg atagtcttta attcacttat caattcatca tattcatttg gcttaatcga
    17221 ttgttttcca tcacaaagtg catgtgctgg gtcattatga acttctatta ttagaccatc
    17281 tgctccaact gcaattgctg ccttagataa agagtcaacc atccatgatt tacctgctgc
    17341 atgacttggg tcaactataa ctggtaaatg actaagtttc ttcacagcta aaattgcact
    17401 taaatccaaa gtatttctag tatatgtttc aaaagttctt atacctcttt cacaaagaac
    17461 tacattttca tttcctccag ccattatata ctctgctgac attagccact cttcaattgt
    17521 agcagataat cctcttttta aaagtattgt tttatttgtt ttacctaatt cttttaataa
    17581 atcaaagttc tgcatgtttc tagctccaac ttgaattaca tctacatttt cttcaaatat
    17641 atctatatct tgtgttgaca ttatttctgt aactatagga agccctgttt tttcttttgc
    17701 tttttttaat aaatccaatc catcatattt caatccttgg aaagcgtatg gtgatgttct
    17761 tggtttgaat gctccacctc tcaaaaatcc tgcacctgat tttttcacat ctttagctat
    17821 agatactatt tggtcttctg tttcaacaga acaaggccca gctatcatag caattttctt
    17881 tgaaccaatt tccattccat taacatttat gattgaaggt tctggatgaa attttctatt
    17941 ggccttttta aaaggctcta ctacatgcat aactttttca actatcttat ttgcttctat
    18001 tcttttggca tctattttac tagtatctcc aactaaacct aaaacagtta attctgttcc
    18061 atctatggga ttaacttcta ctccttctct cccaatagcc tcaattaatt ttttaacttc
    18121 atttttatct gctcccattt ttaatactac tatcattttt actacctccc aatattataa
    18181 ttttatattt aaaataaaaa agagaactca ctaatgagtt ctctaaaata atctatcaag
    18241 cactaaatct tatataaata tataaaataa tcatttttat aaaatttact tatgctcaaa
    18301 atcactaaaa taaggcctca ccagaaagga agtacatata tttttgtaaa agaaatagcc
    18361 agcgctaaaa taaaagcccc agaacataaa gtaaaaaaag ctataaagtt ttgctgttag
    18421 ttcttttaat attcctttca tagtattatc ctccattttt ataatttatt attcttcttg
    18481 tttaataatt ataacaaaga aaatataatt gtcaatattt tctataaata ttttcaattt
    18541 aaaatatttt tttatttact taaatcagct tctcaattga tgtattttta taaaatcaat
    18601 taaacatcat ctgtaattta caataatttt tttattttaa atattataat tccaataaaa
    18661 attatacata gcataaaaaa taaagttgct ggatatccat aaatccagtt taattctggc
    18721 atatatctaa agttcattcc atatatacca gttataattg taagtggtgc tgatatggct
    18781 gttaacaagg ttaattttgt aattaagtta tttgttttct cacctactct ggaagaataa
    18841 atatctaata atttatctgc taactctcgt gttgacaatg cgaaattgta taatttgtca
    18901 attccaaaat ctataccttg aaaattttct aaattatatt tttttacatt tgaatatttt
    18961 aaatatctta tattttcctt aactattcta tccccaatat acaaaagagg tctagtattc
    19021 ttaactataa ttcttgttaa tcctcttaca tcacttattc tagatacatg attcttatta
    19081 atgttgtcca tcatttcatc ttctatttga agaattaact cttcaacttt ttccaaagac
    19141 tcaaaaccat tttttataac ttctctaaga atcaagtagt ttatcttaaa tagattaata
    19201 actggatttt tttcaagttg agagttcttc aaaataatat tttttacaaa ttcaaataaa
    19261 aagtgttctt cattcactac aaccaatata aaattatctg ataaatacat atttacttct
    19321 tctataacag cttctccatc tcttagttca aatgtattta ggcttaaaaa atcgtaatta
    19381 tcaaataaat caagtttggt tatttcatca aatttaagac aatcattaaa agttatttca
    19441 tctatatcca aagtttcctt aagcaatttt aaattttttg gagcacttaa tataagataa
    19501 gaattttctg ctacataaaa tttatctcta aaatcttcaa tagtctctct tgtatttaaa
    19561 ttcagtatat acatacatct actcctaaat ttcaatttac attctaaaaa ttttttataa
    19621 tccttactgt aattatttta cactatttta acaattatta tttaatattt acattaaatt
    19681 tattataagg taagtgttaa atacatttat tatttaacca aagtttttat tacagattac
    19741 actatatact tattttaaaa catatttcat attattgata ctaaaaagct aaaaaataaa
    19801 atgcatgtgc taaactgaca acaagcacat acacttcatt cttattttaa ctaaactata
    19861 taattttaat atatattaat aagcacataa tctaataatt aatatattac aactattcat
    19921 catttaatct gtatcctaca ccaacttctg taattatata tcttgggttt gcaggttgtt
    19981 tttctatttt tcgtcttaat gttgccataa agacccttaa agacttagtc tcattcccta
    20041 taacactacc ccatatttct tttattataa aattatgagt aagcactttt ccatgatgct
    20101 ttgcaagtaa tgaaagaata ttatattcaa taggtgtcaa atggacttca acatcatcaa
    20161 caataacttt tcttttatca aaatcaatca ataatttatc tacttcaaac gtagatttaa
    20221 catcatcttt ttgttgagct tctacttgtg aatgtctaaa tgcgactctt actcttgcta
    20281 ataactctac tatggagaat ggttttgtta agtaatcatc tgcccctgca tcaaatactt
    20341 ctaccttatc tctatcttgc tctctagctg aaactacaat tattggtata tttgaaaatt
    20401 gtctgatagc ttttattacc tctattccat ccatatcttc taagcctaaa tctaaaagaa
    20461 caacatctgg agaatatgag acagcaatag atataccttc ttttccagtt atagcctcct
    20521 tgacatcata atcctgtgtt aaaagtgcag tagatataaa ttttcttatt gtcttatcat
    20581 cctctactaa caatataagt tttttactca tttcttcctc caaaactaat tttaaaattt
    20641 aaaactattc attttcctta ggcaaactaa acttaaaagt tgaaccctta tctttattgt
    20701 tttctaccat aatttcacct ttatgagctt gaattataga tttacaaatt gataatccaa
    20761 gtccaacacc ctttctggaa tctttagctc cttcttctcc agtaaaaaat ctgtcaaaga
    20821 tatgcttttt aagttccttt gatataccag gaccattatc agatacttca aaccaaacat
    20881 aatcatcttt ctcgtataca tttatctcta tcttacaatc ttcctttgaa tatttcaaag
    20941 aattatctat taaattaatt aaaacttgtt ctattaattt tgcatccata ggaacaaata
    21001 atatctgttc tggtatatta atatctataa gtgcattttc aattcttttt tttatttttt
    21061 gtaacgcttc tgatataatt tcctcaacca gttcagaatg ttttttaact tccaatttcc
    21121 cttcatctat cttggtcata ctaagtaaat tttcaacaag tcttattaac cactgagtat
    21181 cttcatatac accactaagt aattcatcta ttatatcttg acctatagta cccttgtttt
    21241 ttataattgt acttactgca ccagatattc ctgctagtgg agttctaagg tcatgcgaaa
    21301 ctgctcttaa aagattactt cttaatcttt ccctttcaat ctcaagattg gtattttctt
    21361 tagcttctga caagatttct ctatcaagcg ctattgccat ttgagcaatt attgtttcaa
    21421 ttaagcttat atcttctgta tccaattttg aatcaataca tgatattcct actactccta
    21481 aagttaaatt cattcctaca attggtatat agtatccctt tgaaccagga agtgtatccg
    21541 tgtcatttcc tgccactgtt gaattggata aaacccaact tgcaacagct ttttcatctt
    21601 cactatccaa atcattttta tccttattat tagtattttt tttgtaaagt tttgatttat
    21661 tatgcttatc tacatttaaa taacaaatta catctctact taagctaaga gacaaaagtt
    21721 ctataccttt gtttactata tcatctttac ttgataatct taaaaatccc ttaattattt
    21781 gatatatcat ttttgtattt tcttctcttt tagcagcagt ttctgcttca tgctgtatct
    21841 tagacgtaag agtgctagtt attataccta ctattgagaa tacaaccagt gttactatat
    21901 agtttgaatc tgctatagat aatgtatata atggtgctgt aaaaaaataa tttaaaagaa
    21961 ctatattaaa tacagaactt attatacctg tactataccc tttagtccac atagaaacta
    22021 aaactacacc caacatatat attaacaata tattttctct tataaatccc atgctttgta
    22081 ctgcatatgc taaaatactt atcatcaaag taataaatat aagttttata aaatcaactt
    22141 tgctaatttt aaatttagat tttattgatg atttatcctt tttaggtttg tatttaacat
    22201 ctgaggcaaa tttatatgga attatatgta tatctatata atcaacttca tcaattaatt
    22261 tgtcaactat atctttttta aatcttttac taaatctttt attacttgaa tgatttctac
    22321 ctattacaat ttttgttaca tttctcagtt ttgcaattct aagtatttgc tctattatat
    22381 tttcaccatg taaaacaatt atttctccac ctaatttctt agctaatttt aggttatttt
    22441 gtagttgttt ttgttcatca aatggaagtc ttgctgtgtt tggagtttca acatataaag
    22501 ctatccattt tgcaaatgta ctgtctgata ttctggatgc agttctaata acttttgctg
    22561 aagatggaga tggacttata catgcaagaa gtgtatctga tgtaggtatt acagttacat
    22621 caccctttga tagtctggtc atttgaactt ctttattaac tctctctgct gtttttctaa
    22681 gtgcgatttc tctaagtgca accaggttat cttttataaa aaaattattt tttgctctag
    22741 tagcttgttc tttcttatat atcttacctt cattgaacct ttcaagaagt acatcaggtt
    22801 caacatctat aagttctaac tgtgtatttg tatccaaaaa cttatctggt atagtctctt
    22861 taactgatac gtttgtaatt acctcaacaa tgtcatttag actttctaaa tgttgtacat
    22921 ttacagtagt gtagacattt atgcctgcta acagcaattc ttctatatct tgccatcttt
    22981 ttgtatgcct taacccagca acattagaat gggcaaattc atctactaat ataacttctg
    23041 gttttcttgc taaagcagca tctaaatcaa attcttttag ttttatagat ttatattcta
    23101 tctcctttac aggaagaatt tccaagccat caagtagagc caatgtttct ggtctagtgt
    23161 gtggttcaat atatccaact actacatcta cacccacttt ttttaaattt tgtgcagatt
    23221 ccaacataga gtaggttttt cctactccag ctgcataacc aaagaatatt tttaattgac
    23281 ctctacttag tttttcttct tcatttttaa ttttttctaa tagaatatca ggattaggtc
    23341 tatccattaa aaaacctcct tacaccattc attactatta taatatcaat tccgatataa
    23401 aattgtagtt aagatgtatt tttaatgatt aagattatgt aaagatttaa atatgaattt
    23461 aaaaaattta gttgtaaaat aaaaatgcct aacaataggc atttttatct tgtgtataat
    23521 cattttagtt taagttaagt atttccataa actcatcacc tgtaatagtt tctttttcta
    23581 ataaataatt agcaagttca tgcaatttat caatattatt ttctaagatt tcaattgcat
    23641 ttttgtgaca agcctttact attttaaata cctcttcatc tattttagca gcagtgtcgg
    23701 aagaacaagc aagagaagta tctcctccta aatattgatt gcttacagtt tcaagagcga
    23761 ccatatcaaa ctcttcactc ataccaaggc gagtaaccat agctcttgca attttagtag
    23821 cttgttctat atcatttgat gctcctgatg tacaagtgtt aaagataacc tcttcagcag
    23881 cacgaccacc tgtaaaagta gttattttat caattgcttc ttctttagac ataagtacac
    23941 tctcatcttc agcaacttgc atagtatatc ccaatgctcc tgaagttcta ggtattatag
    24001 taatcttatg gacaggtgca gaatgttttt gcatagcagc aacaagtgca tgacctattt
    24061 catgatatgc tataattttc ttttccttat ctgaaattac agctccttta cgttgatacc
    24121 cagcaattac agtttcaaca gattcatcaa aatcctgttg ttctactata tctctgccag
    24181 acttaactgc taaaagtgct gcttcgttta caatatttgc aagttctgca cctgatgctc
    24241 ctgatgtaga ccttgcaatt gcattataat ctatatctga gcttacattt acattttgag
    24301 catgtacctt taatatagct tcacgtcctc caaggtctgg aagttcaact ggtatacgtc
    24361 tatcaaatct tcctggacga agtaatgctt tgtcaagact gtcaggtcta tttgtagcag
    24421 caagtattac tactccaatt ccaccatcaa aaccatccat ctcacttaac aactgattta
    24481 aagtttgttc acgttcatca tttccaccta atccacttcc attatcacgc tttttaccaa
    24541 tagtatcaat ctcatctata aacactatac atggagcttt ttcttttgct tgtttaaata
    24601 aatcacgaat cctagaagct cccattccta caaacatctc aacaaactca gaaccagata
    24661 ttgagaaaaa tggtacattt gcttcacctg ctacagcttt tgcaaggagt gtttttcctg
    24721 tacctggagg tcctactaaa agtgctcctt taggcatttg tgctcctatc tttttatact
    24781 tttctggatt gtgtaagaaa tctactattt cagttaaagc ttcttttgcc tcatcttgac
    24841 cagctacatc attaaatctt tttccacttt gagcagatac atacattttg gcgttgcttt
    24901 ttccaaattg catagcatta ccacccattc gcttttgcat agacttcatc attaagttac
    24961 caaatagcat aagaatacct ataggtatta tccatgtaag taaaatactt aaaagaggtg
    25021 aattttcctt aggaataacc ttagtaaatt ctacttttgc attttttagt ctatctacca
    25081 attctgggtc atccattcta ccagttatgt atatattctt atccttgcta ctagatggat
    25141 ttattgctat tctattattt tctatctcaa cagatttaac ctttcctgta tccaacattg
    25201 tgagaaactt tccatagtca atctcaacca tttttttatc cattaaactt ggaaatatta
    25261 aagcatttaa aaacattact actattatta taactgtata ataatagagt gctgaccttt
    25321 tttggggttt atgttcatcc ataattttat tctcctttaa attattttta tgttatttgc
    25381 aatcaatgta agttaaaagt ttatttaatt tctctaaacc ttctattata tcttccatat
    25441 cttgcaattt ttcactggtc atattttcaa aataactatc aaaaatacta cttgaaatat
    25501 gttcttgtat atccaatgat ttatttgtaa cttttacttt tacaattcgt tggtcttcta
    25561 tatctcttat gcgatttaaa aagccatttt tttcaagcct ttgacagatt actgatacat
    25621 tactatttgt catgtttaag ttcttcccta aatcgcttat ttttttctct ccatgttcac
    25681 ataactcaga taaaatcaaa gcttgcactg ctgtaatacc aagtggctga taaaaatcac
    25741 ttaataaagt tgtaaatttc atatttatat ctctagtcaa ctctagtagc tctttcttaa
    25801 aactcatctc atccatacaa acgctcccta cgaaaatact ttatttcaaa tttaggctga
    25861 agtgcatact gtaaataaat acttaatact ataatgttta atgtattaaa tattatagta
    25921 ttaagtattt attgtcaatt acaatattgt aacttcaatt ggaattttgt tatcttattg
    25981 atatttaatt ttatacagga tatttttaat aaaatttaat aaaaaatcga tatatatatt
    26041 ttacactgat ttctcccttt ttaatctctt ttaaaagtta aaatacaaat ttattgatac
    26101 tataaaggtt tagtctccca ttatcgcacc atatataaaa ttaaaaccac ctctatctac
    26161 atacacctaa agtgattttc ttaaaatata aaactactat tataaggtta aatttaaaaa
    26221 aaataaggta taaagtatca ttaagattaa ctttatacct ataaatttct atattttttt
    26281 agttaacatt tatatactct taaaatttat tgtatcaaat agttttttat ccaatttcta
    26341 aacaacaatt ctgaatgttt tttccatttt acagttggct cttctgaagg gtcatcatta
    26401 atatagtaat tttgaggtat agatatttta tctcctttat ttatatccct cttatattct
    26461 ttatcaagag tgtatttgtc atactcgcta tgacccatta cgaacacatc tcttgaattt
    26521 gtaattatat agggaccagc ttctttagaa tgactcacaa tgctcaactc tttattctct
    26581 ttcaaagctt caatatttac agtagtatgt cttgaatgtg gagcaaaaaa ttcattttca
    26641 aatccatcta ctattttact atctttatct accttatgct taaatactcc aaaacatttt
    26701 tgacttagtg gaagtttttt tacattgtag tatttgtaaa gacttgcttg agctgcccaa
    26761 catatatata atgtagattt agtttttctc ttagaataat ccataatttc ttctagttca
    26821 ttccaataat caacttcttc aaactccatt tgttcaactg gagctcctgt tattataaag
    26881 ccatcaaaat actctccttt ggcttcatca aatgttttat aaaattcttt aacatattca
    26941 ttacaacttc ttttactttc tcttgttgaa attttaataa attcaacaga cacgttgaat
    27001 cctgttttat ctatccttct tagtaaatct aattctgtat ctatctttat aggcattaga
    27061 tttagtatag ctattttagt gtctatgttt tcttcatact ttaattcctt tttaaaatct
    27121 tctttataaa ttacatctat tccttcatct aataatttat taataacagg taatcccttt
    27181 ggtagtatta aagccatatc ttttcacttc tctttctctt agaatattag aaatttaaag
    27241 cttgatttaa atcagctatt aaatcctcta cattttctat tccaacagat aatcttatta
    27301 gtgaaggcaa tactccagat gcaattaatt gttcttctgt taattgtcta tgagtagttg
    27361 aagctggatg tataacacaa gttcttacat ctgaaacatg tgtaaccaaa gatgctatct
    27421 gtaatttttc cacaaatttt ttggcatttt ctaacccacc tcttactcca aatgataaaa
    27481 caccactaca tcctcttgat aaatactttt tggcattctc ataatacttg ttatcttcaa
    27541 gtcctgggta attaatccaa tctacatttt catgtttttc taaaaatcta gctattttaa
    27601 gtgcattttc actatgtctc tccattctaa gatgtagtgt ttcaacattt aaattagtaa
    27661 gatacgcatt gaatgggctt aaacaatttc catagtctct aagcaactga actcttgctt
    27721 tagttgcata tgcggcattt ccaaattttt gagtatagct tattccatga tatgttgggt
    27781 ctggctcaac taattctgga aattttccat tatcccagtt aaagtttcca ccatccacta
    27841 taattcctcc aacacttgaa gcatgcccat ctaaatattt tgtggtagaa tgagtaacta
    27901 tatttgctcc atactttaaa gggttacaaa gcactggaga tgctaatgaa ttatcaacaa
    27961 taaatggaac attaattctc ttagctacat ttgctatttt ttcaaaatct atgacttcaa
    28021 gagtcggatt tgcaagtgtt tctgcaaata caaccttagt attttccttt gcaagttcta
    28081 ctatctcatc ttcacttgaa tctaagtcaa acgatattaa atctatacca aattttttaa
    28141 gactaggtcc tagtaaattg aatgttcctc catatacttt tgaagaacaa agtatactat
    28201 ctcctgattt acatatattt aaaactgcca acatatttgc agattgccct gatgatacag
    28261 ctacagaaga tactccaccc tctagtaaac ttattttttc ttcaaaagct tgaatagtag
    28321 gattgcttat tcttgaatat atatgtccat caacttttaa atcaaataat tcagcaagtt
    28381 ggtctatact gctatattta aaagttgtac tttgatataa aggtaatact cttggttctc
    28441 cattacctgg tttataattt ccttgcacac atattgtttc tttattatac attcttgtat
    28501 cccccttaga ttttagtaaa aaaaattaaa ctatttatca gatgagagtt aaaataaata
    28561 aagcctgagt atataactca ggctctgtat aagcttaatt atactcatct ctcagctttc
    28621 gccgcaggat ttagcaccaa tgtatataaa tatactggtt gccgggtttc atagggccag
    28681 tccctccacc tctctggata agatttattt aatttttcta tgttttatat cttatatatt
    28741 tttcctaatt ttgtcaacta tttttttctt ttttttcttt taataatttt cccaacctct
    28801 acttgaatta cagacattat ggctaaaaca atcgttataa gccactctaa gttatttaaa
    28861 actgttaagt taaaagcatt tctaaaaaca ggtacaaaca gtattactgc tattaaaaat
    28921 gcagaagtta aaaatgagat taaaagaaat ggatttttac cattatttct attaaacatt
    28981 gaatctgtat ttgaacgctg actaaatgct cgtaacatct gtgaaaatgc taatacacaa
    29041 aatgccattg tttgacctac agaatgattt tctatattaa gaccaatttt atatgctaaa
    29101 atagtcatta ttgccacaaa tataccttgg gtaacaactc tttgtataag atttttttca
    29161 aacaaagtgg ttgatttcac tggctggtgc ttcattatat ttctgcttgg tgggtcaact
    29221 ccaagagcaa gggctggaag cgtagcagtt gcaaggttta cccatagaat atgaacagca
    29281 agaagcggag tatcccaatt taataatatt gctacaaaca acgtaagtat ctctgctata
    29341 ttaccaacaa gcaaaaattg tataactttt tgtatgtttc tatatacacg tctaccttct
    29401 tttattgcat aagcaattgt tgtaaaacta tcgtccatta aaatcatgtc agaagaatct
    29461 tttgcaacat ctgtaccact tatacccatg gctataccaa tatcagcaga ctttaaggca
    29521 ggagagtcat ttacaccatc cccagtcatt gctggtactt ctccaattct ttttagagat
    29581 tgtataattc taagtttatc aaacggggac acacgagcaa atactgtagt atttttaaca
    29641 gcttcatcta gttcatcatc actaaaatta tcaagttcat caccagatat cacagtattt
    29701 tcttcactcc atattcctaa ctcatgagcg attgttgtgg cagtaacttt atggtcacct
    29761 gttatcatta tggttcttat acctgcttct ttacaagtac ttactgcatc aattacctca
    29821 gttcttggtg ggtcaatcat accaaccata cctataaatg tcaaatcata ttctatattt
    29881 tcactatctt cttttggtat agatgaaatc tcacgcttag caaaaccaag tacacgcaat
    29941 gcatctttag acatgttaag acataattcg tgtatattct ttttatccac ttcggtaatg
    30001 tttctttcac cttttgaagt taatatttta gtacataggt cgagaatttc gtctactgct
    30061 cctttagtat aagcaataat cttttcatct atattatgaa cagttgtcat acattttcta
    30121 tctgaatcaa aaggctgttc aaatacacgt ggatattctt cttcaagagc ttcttgatct
    30181 attccaaatt ttttggccat aaaaattaat gcgccctctg ttgggtcacc taatatttca
    30241 tctgttttat ctggattaat acatgcatca ttacaaagtg caccagcata aacaatctct
    30301 ttatacacta atggatgttt ttcagatgca gtatctattg atgtcacttt tccagattca
    30361 aaatctccat tgacagcaat atgtgtaaca gtcattttat ttaaggttaa tgtaccagtt
    30421 ttatcacaac atattactgt agctcctcct aatgtttcaa cagcaggtaa ttttctaatt
    30481 aaagcatttc ttttagccat acgctgtacg cctaaagcca ttacaatagt agctgttgca
    30541 ggtaatccct ctggaataat tgatatggca agggaaattg caatcataaa cattggcaag
    30601 agaggtctct gataaaatgc acctattgca aatataacaa cgcatacaat aatacctatg
    30661 acacttaatg tctttccaac agtattaagt ttacgtttta taggagtatc aaaatcatct
    30721 tgtgaatcta aaagatgtgc tatgttaccc acttctgtat ccataccagt tgctactaca
    30781 acacctacac ctctaccata tgtgactatt gaagatgtat acgccatatt gctacggtct
    30841 cctaatacac attctttagg taagattgta tctgcatctt tttctgatgg aacagattct
    30901 cctgttaaag aagcctcttg aatttttaaa cttgatgttt ctattaaacg aaggtctgct
    30961 ggaaccatag ctccatcttc taaaaaaaca atatctccta ctacaagatt acttgctgga
    31021 ataacatttt cttcaccatc acgcataaca cgagctgtag gtgagttcat attttttaat
    31081 gcttctaatg atgattctgc ttttttctct tgaacaattc caataactgc atttactgtt
    31141 acaattatta gtattacaaa agcttctgta aattcgccaa atatcaaaga taatattgct
    31201 gctcctatta gtatcataac catagcatct gtaatttgac tccaaagcat ttgtaaagtt
    31261 gttctaggtg gtttttttct aagttcattt aagccattct ctttaagccg tttttccgcc
    31321 tcggtatcgg tgagcccctc ctctgatgaa tctagacttt ctaaaatttc atgcgttgct
    31381 cttgaatgcc aaggcatctg tttgtgattt tccattttgg aagaccactc ctttcttttt
    31441 ttaatttaag aataattata ttttaaaatc aagttcaatt caatacacac taagtatatt
    31501 ttacctaaat ttaacaatgc catttaatat ttaacaaaac ttctactctt ttacaaatat
    31561 gtattcacta ttgttagata agttttcttt atacttataa ccttctaaat taaacttttt
    31621 cagttcttca atatctctta tcctattttt tacaatgtat tttgtcatca tacctctagc
    31681 tttctttgct tgtgtagatt ccactttcaa tatgccattt ttatttactt taaaagtaca
    31741 tgtaatatat gtatcactat ctttaataaa tttttctatg gacttgctgt attcatttga
    31801 tgaaagatta atgatagctg ttttttcttt gattagttct ttatatatac gatttcccca
    31861 atattcgtat aaattcttaa actcacctac tcgtaatttt gtctgcattt ctaatctata
    31921 ttcatatata ctatcatatg gttttacaac accatacaat ccacttatga ttcgaataca
    31981 gctatttgca aactcttcat ctttccttgt aaaattttct gcttctatat ttttatattg
    32041 tattccatca taagttaaga ttgcagggtt tcctaatcta tcaaatttaa tgctttcaaa
    32101 tctattttta tttaatacag ctaatttttc attaattttc attttatttt taaaatcttc
    32161 tataccaaat gtctttatat tttccactat ttcttttgtg ttatctataa aacaaggcaa
    32221 actcaaatct ctatcaaata cttctatatt cttcatattt ttagctggtg ataacattat
    32281 aatcataaat tcttattact cctgtttttc caaatattca agaatctctt gtgcatttgt
    32341 gtctggtttt gctttttcaa agactttttc aataattcca ttttcatcta taatatatgt
    32401 cgcacgtaca actcccaatg cagtttttcc atacattttt ttctctttcc atacatcaaa
    32461 agcttttata gcaactaagt cagggtcaga aagtaaaata aaaggaagtt catgcttttc
    32521 tgcaaatttt tgatgtgatt ttatactatc tttacttatc ccaataactt gtatatcttc
    32581 ctttttaaat ccatcatatg catttctaaa agcacaagct tgacgtgtac atcctggtgt
    32641 attatcttta ggataaaaat atactactac ttttttgcct ttaaaatctg acatacttac
    32701 cttatttcca tctttatctt ctagtgtaaa ttctggtgct tttgttccta tactcaacat
    32761 aaatatctct ccttttgttt ttattaataa ttttatacta tgcttatatt attaccctat
    32821 aaatctatat ataaataaaa tattttattt tttatgtata aagtttcata aatatataat
    32881 tttcatgtat ttatattcta aaatagactg aaaatagttt tattaagata tctatgctta
    32941 aaacaaggtt aaatgataga ttaattaaaa taaggatatc taaaaataaa atttttagtt
    33001 cattagatgc tcttttttgt atgaaatcaa atatattttc atcatttcaa caataaaaag
    33061 agacttatcc ctattttgag aaagcctcat ttattattac ttttatatta tctatataaa
    33121 tttaaattcc tcaacatcaa atagacctaa atctgtaagt cttatttgtg gaacaactgg
    33181 aagtgccata aaagaaagtg taataaaagg gtctacatac tctggaactc ccatttttct
    33241 tgctatctcc aacatattat cagtaatttc ttgtacttct tcagctgtaa aagtactaat
    33301 taatccagct acttgaagac ttaggtgtgc aagaactttt ccatttgata caattacata
    33361 accaccttgt atttccttta agtaatttat agctactaga atatcatcat cattatcccc
    33421 tgcaactata atattatgag aatcatgggc cacagtagta gcaattgctc cattttttat
    33481 gccaaatcct tttagtgaag caattgctac atttccagtc attctatgtc tctcaacaac
    33541 acaaagtttt gaatactctt tatttggaac aaaatatcca tctgcacatg gtaaagattc
    33601 atatacctta tttgtcaaaa tttgataagg tacaatctcc attacataat ttttttcact
    33661 tacttttaac tgtatttttt ctttattaat atacttaaac ttgactgtat taagcaattc
    33721 tttatcttta atctcataat tgtaattaga aaacatctct tcgtttacca aattaccatc
    33781 tttatataca ctatccactt ccattttgtc taaatcattc aatacaacaa tatctgcctt
    33841 ataacccgca cctattgctc caattttcct taacccatat gcttttgcag aattataagt
    33901 tgcaactttt atagccctaa caggttccat acctaaatca atcgcacatt ttatattcca
    33961 tcttatgtga ccttgttttt ctatatcatc taagtgctta tcatctgtgc aaaacataaa
    34021 ttcttcaatt ggcaagttat gctttagcat accacttact atagacttta aattttttgc
    34081 tgcgcttcct tctcttatta aaatttttaa tcctgctctc aatttttcat atacttcatc
    34141 aaaagttata cattcatggt cattttctat tcctgcacat acatatgtct gaagtgattt
    34201 accatttata ttaggtgcat gtccatctac aactttattt ttaaaaagct ctagtttatc
    34261 caagatttca ttttcagaat ttataacatc attaaaacac attacctctc ctaaacctaa
    34321 aattctagga ttatttacat aactctccat gtcttttgca ctaaatttac caactccatt
    34381 agtttcaaaa cttgttgcag gtacggatga aggcaccata atatatacat taagtggtat
    34441 atcttttgtc gattctaata aaaaatctat tgcactagct ccttttacat tgaccaactc
    34501 atgtgggtcg gctatgatag ttgtcgtacc tgattttaat aattttttcg ataattcaat
    34561 tggcattacc attgtagatt caatatgcat atgtgcatca ataaagccag gtgatatata
    34621 tttattgcta caatcaattt ctacattgcc cttgtaatcg ccaatgccaa cgatagtgtc
    34681 tcctactatt gctacatctc ctgttattaa ctcttctgta aatacattta tgattgtccc
    34741 attttttagt acaatgtcag ctttttctct tccacttgaa acatcacact gtctttttaa
    34801 attacccatt tttacaactc ctcctaagtt ttttatatca atatactggc tgtattacgt
    34861 attatagttt aatttattaa tatatattat atatgagttt tgatagaaag tatcacttga
    34921 aatttgttcc ataattcctt taattaaata gagagaacat gaggaataat attatctccc
    34981 atgttctcat taatatttaa gcaataattt aattcatatt gaatttttta tttttatatt
    35041 taatcttcac tattcttata aataaattta tgtgctttat tattttttta atacttcttt
    35101 attcgtaatt atatttaacc taaaaatgca taaactatca tacctacaag tattgctggt
    35161 atagtagtaa taatcatagc ccataaagaa gattttttat ccattgctaa aagtgggaaa
    35221 agtgcatctc catcttgaga aatagagttg gctatcactg caccaagtgg tatagttccc
    35281 ttcaaataaa atgacataag cacaatttgt atcccacaac ctggaataag tccaagacct
    35341 gcacctataa atacacttat tacacctgtt gataatacta gtttaactaa gtattcatct
    35401 ccacctaaaa ttaatattat caaatcgtaa ataagatatg caataaaaat ccatgtaatt
    35461 acaaatgata tttctccaac agaatggata agcatttctc gcaaagaaat ctttttattt
    35521 tcttcctctt tttgattaga atttttaaat acctttttaa aacaccacat ataaattatt
    35581 gaaaataata ttccaatcac tgctattact tcttccaatg aatgtaactt ctcaattata
    35641 ggaagattaa gtccagagtg agcaagtgac ataaatataa aaccgattac tataattcct
    35701 atataaaatt tatatccctt tccatgtgtt attataaatg caagtctatt tgtatttcca
    35761 tgagatttag ctagagtgtc taaaattatt tcatcatgat tatgttgttc tttattttct
    35821 ttagggttat ttttacttat atcatattta tctgattttc tacggttttt taaccctaat
    35881 ttttcttcta gtttaaagta atccactaat tgtcccgtta ttattcctgt aattgtacta
    35941 actatagtga caaaaaaata cattttaata tttgatgaaa taagtacaaa tgctgcatct
    36001 cccatactag ctattaaact tgcaattatt gctccaaagc ttaattttcc atttatatac
    36061 aatggcatta ttgccagact tccgccacaa cctggtatag ctccaattaa agcacctatt
    36121 aagggttgaa attttctgtt ttttgatatg atattagtaa aatttccact agttttataa
    36181 ttaatatatc caaataacaa aataaaaaat ccaatcatag aacctacatg taaaaacgcc
    36241 tcttcagaag cggatatcaa catttccatt aatttacctc ctagactaat tttgcaacaa
    36301 ttatattata ttctattttc tattgataat caatatcaat atttcttttg aatttttaat
    36361 attaaaaagt gcgcatctta tactcttagt ttttcatctt aagatacaca ctttttgata
    36421 ttaggttatc tatttaccac atgtaatatg aaatcaaagg tggatattat gataaattat
    36481 aacaatgtcc acctattttt attacctatc aaattataaa ttttcaagga atgttacaac
    36541 ttcttctatt atccaattag gtgtagatgc ccctgctgta atacccaaat ttttatattt
    36601 tttaagcgta tttacatcca attcatcttt agtctctatt gcaaaagttg gtactaagtc
    36661 ttcacaaacc tttactaact tttgagtatt tgaactgtgt ttacctccta taactatcat
    36721 acaatcaact tctttagcta actctttagc tgattcttgt cttgtttttg tagctgaaca
    36781 aattgtatca ttaaatacta tttcttctaa tttatctgat agtttattaa ctatacttat
    36841 atacaactct ggatttattg tagtctgtgc aacaagacaa tattttttgg agttattaaa
    36901 ttccatattt tccatttgtt ctaaggtctt tattattata gctgaatttt cacaccatcc
    36961 atttatacct ataacttctg gatgcttcat atctccaata actattattt catagccttt
    37021 attatgatat tcacttacta ctgtatgtat tttctttaca aatggacatg tagtatccac
    37081 aatttttaat tttttatctt tggcttcctt atatatattt tcaggaactc catgagacct
    37141 tattatcata ttttcatgat ttggtattgt atcaatttca ttcacagtct taagaccttt
    37201 ttcttcatat tttgctactg cttgcttgtt atgaataaga ggacctaaag catatatgcc
    37261 agaatcattt ttttcaactt catcccatgc cattttcatt gctcttttta ctccaaaaca
    37321 aaagccagca ttttttgcta tttttatgtt cataacttta cccccttatt ttgaatattt
    37381 aaagtaattt tgttttatca cttctaaaat ctcttgtgat atcctttcat ggtcatcatt
    37441 actcaatttt tccttaaaat gttcttcaaa tgatattggt tctccaatat atacaattac
    37501 tttactaaaa agtttatatt tagatattat tgatactgga acaactttag atttactttt
    37561 tattgtaaat acagaaagac ctgccttagc cttaccaaaa gaatctcctt ttattctagt
    37621 accctctgga aatattccta atacataacc atctctaact gaccttaaaa tagtttttat
    37681 tgtagataca tctggttttt ctctatttat aggcataaca tgcaattttt ttaatataaa
    37741 tcccaatggc tttactttaa acaattcttt ctttgcaatt gcagctattt ccctattttc
    37801 tatggcagca gccaagaata tagggtcaag attcgattta tgatttgatg ctattactat
    37861 atttcctcta tctggaatat tctctgcacc tataacttca tatttaaaaa atattttaga
    37921 aaaaccctta aaaatattta ttacaaatct ataaaaattc acgtttatct cccttcaaca
    37981 ctacatttat tttcattatg atgcataaaa aactaaagat ttattttaga tacaacttct
    38041 tctacaactt cttctatagt ttttcctgta gtatctattt ctagtgcatc attagctttt
    38101 accaatggtg caaattctct atttgaatca atttcatctc gtcttattat atcctcaatt
    38161 acttcttcta aagtagtatt atatccttta ttacaaagtt ctttatagcg tctatttcct
    38221 ctttcttctg gagtagctac taaaaagaat ttgtaatctg catctgggaa aacatatgaa
    38281 cctatatctc taccatctag tattactgaa cttttcattc ctatttttcg ttgaacttca
    38341 accatcaact gtcttacttc ttttattttt gctacattag aaacattatt gcttacttct
    38401 attgttctta tttcttcatt tataacttct ttgtccaaat atatattgtt atctttaaaa
    38461 tctatatccg aattttcagc tatttgaata acttcttttt cattattgac atcaacacca
    38521 ctttttaaac acttataagt aactgctctg tacatagcac ctgtatctat ataatttata
    38581 tttagctttt ttgctactat cttggctatt gtactttttc cagctcctgc tggaccatct
    38641 acagctataa ctaaattacc catatataca cctctattta ttcatattta attattaaaa
    38701 aattatattt atacacttat acccgcaaga tatccagttg aaaatgctat ttgtaaatta
    38761 tatccaccag tttctgcatc tatatcaatt acttcacctg taaaaaataa gttcttaact
    38821 aatttagatt ccatagtaga agaattaatt tctttaactg aaataccacc agaagtaacc
    38881 ataccagtgt ttatacctgt agtcccatta caagttagct tcatattttt tatatactca
    38941 ataattctaa tttcatctgc cttagacaaa tcacttgcct ttttatcaac taaagataat
    39001 agagaaaaaa tctctcttaa gaaattttga ggtagtattt gcttaagatt atttagaaca
    39061 tttttatttg gaaatgctct gattatacta gagatttcat cagtacttaa atttggtaag
    39121 aaatctatat ttaattctac cttttccttt tcaataatct tgttaatata agaagacatt
    39181 ataagaacac aaggtcctgt tatcccaaaa tgggcaaata gcatgtctcc agattttgat
    39241 attttccttt tcttaatctt acaagatatt tccacattct tcatggatat tccttgtaaa
    39301 tctttaatcc atttttcctc tattgtaagt ggaactaaag caggatatag tttgtttaat
    39361 gtatgtccat gctttttaag aatcttatac attgaaccat ctgaacccgt ctttgaataa
    39421 ctcactcctc cagttgatat aataaccttg tctcctagta tcttatctcc attatctaaa
    39481 ataatccctt ttattagata ctttgacttg tccttattag aatcatcttt tagagcaatt
    39541 tcttcagtta taatatctat aactttctta ttatacatta tctttacatt gtgattgagt
    39601 aaatctttat ttaatacttc tattacttct atagatttat catttttagt gtatactttg
    39661 tggtcatttt ctttttcaat cttatattcc aaatttctac tttcaaaata cgaaataagg
    39721 tctttatttg taaatgtata gaaactacta tagagaaatt ttttattact gacaacttta
    39781 tcaaaaaaat cttctatctc tctattattg gtaaaattgc atctaccgcc accagttgcc
    39841 ctaagttttc ttcctaattc tccatttctc tcaactaata ttacttcatt attgtttttt
    39901 gaagctgaca aagctgccat cattccagaa gctcctccac caactactat aactttactc
    39961 ataaatttct ccttataatt gattcctact ccagtgcaga attatttatc tttacatgat
    40021 tttttatatg acttgtatca ttcattttta ctataacagg tccataatct ttaaattcta
    40081 ctatatttaa agcagtatta tcttgcttaa ttctatatat attttccata cctgattcta
    40141 aaaatgacaa caacataacc ctcaatgtaa ttgaatgtgt aacaagaatt atatttttat
    40201 tatcatattt ttcatttagt tcctttataa aagcatctac tctttccttt ataatcttaa
    40261 gagtttcgcc ttctggtata tttactaagt gtggttcatt tctccatgtt gcatatatat
    40321 ctgaataatc tttttgaatt tcttttatta aaaggccttc ccaaactccg aatcccattt
    40381 ctctaagtgc ctcagttttt tgaacttcaa tattgagctt atctcctaaa atttgagctg
    40441 tttgcattgc tctcccaagg tcgctactaa aaatataatc aattgaatac ttgccaatat
    40501 cttcagaaag ttcttttgcc tgttctatac cttgaggcgt aaggtcagaa ttaccatgac
    40561 cttgtgtttt tcccaatata ttccaatccg tttgtccatg tcttactata taaaaagtat
    40621 ttcccatatg tcctcctaat atatgcctat tttttattaa atataaatta tcacttctca
    40681 aaacttaatt atatcatata atactttact ttgtttctat tttataatct aatctaacat
    40741 attatttaca ataaatctca tttgtatttc tgcaaattat tgtactgtta aagaattttt
    40801 ctaaatttat aaacatattt ctcttatatt atttatatac ttcttcaaat ctgtattctt
    40861 gaattgaatt gacatactta tctgtatcta ctttttctaa aaacatatcc aaaggtcttg
    40921 caaatattcc tgtatcatca tataaggtct tgtataaaac taaatcatta gtatcttctt
    40981 cttttttatg ataaaggttt ccatctaaat ccctataaac atagatatct tcttctcttt
    41041 cagtatgtct aataactaat ttatatttat ttctgttttg gattaaattt tctttaccat
    41101 atatttcaca tatgttttct atatcatcaa tagccttgct aagacccatt gtagcataat
    41161 atttcccttt aaaatgttta tagatacaag gatattttaa ctttctttca ctgataccta
    41221 agttattctt taattcaatc attttattat aatctcccat atctcgtccc tttcttttaa
    41281 aaagtatttt attctgaaat aagttacttg ttttatattt tatcataatt taaaatttat
    41341 taataataca atcaataaat aaagaggctg tataaaatac agcctcccaa tattaatctt
    41401 cataatcata taatttttct aatttctttt ttaatttctt ttttctttct gaacctaaaa
    41461 ttcttataaa attattattc acaaaaatac aattattgct gagataaaat tcacacttgt
    41521 ctagatttac aatataacta ttactgcatt tgaaaaaatt ttcttctttc aatagttttc
    41581 ttatacaagg agcattttct ccaacttcat aattaccact ttcagtataa atctttactt
    41641 catactcttg cttttctatg tacaaaactt ctttactatt aattgaaaaa cgtttatcct
    41701 cgtattcaac attaataaaa ttttcctctt tcatttccat ccctccaagt acttttatta
    41761 atttaatttt agtgtttttt atcaatataa tctatcggaa atatatgtaa gactgattta
    41821 cttaagatat ttaaataatt attattaata ttaatgtata agtttatttt ttaacattaa
    41881 tttttaaagt taaaaagact tttttt
//
LOCUS       DAMJWO010000032        41740 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.033, whole genome shotgun sequence.
ACCESSION   DAMJWO010000032 DAMJWO010000000
VERSION     DAMJWO010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41740
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.033"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(133..1098)
                     /locus_tag="PC366_001696"
     CDS             complement(133..1098)
                     /locus_tag="PC366_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2577226.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKKNESKTSENSNNTIKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAENLVGLPKTSLPASLEKYKDKKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
     gene            complement(1190..1945)
                     /locus_tag="PC366_001697"
     CDS             complement(1190..1945)
                     /locus_tag="PC366_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2577227.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRSLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVEKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            complement(1942..2898)
                     /locus_tag="PC366_001698"
     CDS             complement(1942..2898)
                     /locus_tag="PC366_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDF2577228.1"
                     /translation="MKLSLNQKIYFVSILLFISIALFIIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKMLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            complement(2888..3841)
                     /locus_tag="PC366_001699"
     CDS             complement(2888..3841)
                     /locus_tag="PC366_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDF2577229.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RVPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRASIWYTGLLGAVFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            complement(4088..5068)
                     /locus_tag="PC366_001700"
     CDS             complement(4088..5068)
                     /locus_tag="PC366_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDF2577230.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLTEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLMSVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKDILK"
     gene            complement(5125..6327)
                     /locus_tag="PC366_001701"
     CDS             complement(5125..6327)
                     /locus_tag="PC366_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HDF2577231.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            6522..7076
                     /locus_tag="PC366_001702"
     CDS             6522..7076
                     /locus_tag="PC366_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF2577232.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTQKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            complement(7191..7982)
                     /locus_tag="PC366_001703"
     CDS             complement(7191..7982)
                     /locus_tag="PC366_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HDF2577233.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYANIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKPDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDFSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFKGMSGTEEILSNILDENCLLNI"
     gene            complement(8010..9098)
                     /locus_tag="PC366_001704"
     CDS             complement(8010..9098)
                     /locus_tag="PC366_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HDF2577234.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNVSLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKHFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLIGKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            complement(9152..10390)
                     /locus_tag="PC366_001705"
     CDS             complement(9152..10390)
                     /locus_tag="PC366_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HDF2577235.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGVRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELNCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKKHYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            complement(10368..11444)
                     /locus_tag="PC366_001706"
     CDS             complement(10368..11444)
                     /locus_tag="PC366_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HDF2577236.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNSHSITGILIPKANSELIENCIEALYSMNLQDMYVI
                     PIIETREFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            complement(11508..12644)
                     /locus_tag="PC366_001707"
     CDS             complement(11508..12644)
                     /locus_tag="PC366_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDF2577237.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            complement(12645..14207)
                     /locus_tag="PC366_001708"
     CDS             complement(12645..14207)
                     /locus_tag="PC366_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HDF2577238.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGVIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDIHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            complement(14294..17053)
                     /locus_tag="PC366_001709"
     CDS             complement(14294..17053)
                     /locus_tag="PC366_001709"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HDF2577239.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            complement(17043..17672)
                     /locus_tag="PC366_001710"
     CDS             complement(17043..17672)
                     /locus_tag="PC366_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2577240.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            complement(17758..18336)
                     /locus_tag="PC366_001711"
     CDS             complement(17758..18336)
                     /locus_tag="PC366_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2577241.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLRHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            complement(18375..18953)
                     /locus_tag="PC366_001712"
     CDS             complement(18375..18953)
                     /locus_tag="PC366_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2577242.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            19282..20718
                     /locus_tag="PC366_001713"
     CDS             19282..20718
                     /locus_tag="PC366_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDF2577243.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKSSSYIKEVHFTRY
                     IGVDDSIDKYIEKVKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYDSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWM
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIAQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESNLVKIFANNFIEIVN"
     gene            complement(20810..22684)
                     /gene="asnB"
                     /locus_tag="PC366_001714"
     CDS             complement(20810..22684)
                     /gene="asnB"
                     /locus_tag="PC366_001714"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDF2577244.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEYVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            22887..23561
                     /locus_tag="PC366_001715"
     CDS             22887..23561
                     /locus_tag="PC366_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HDF2577245.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            23674..24210
                     /locus_tag="PC366_001716"
     CDS             23674..24210
                     /locus_tag="PC366_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDF2577246.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(24376..24996)
                     /locus_tag="PC366_001717"
     CDS             complement(24376..24996)
                     /locus_tag="PC366_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDF2577247.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(25310..27448)
                     /gene="vanT"
                     /locus_tag="PC366_001718"
     CDS             complement(25310..27448)
                     /gene="vanT"
                     /locus_tag="PC366_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HDF2577248.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            complement(27466..28272)
                     /locus_tag="PC366_001719"
     CDS             complement(27466..28272)
                     /locus_tag="PC366_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2577249.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            complement(28269..29369)
                     /gene="vanG"
                     /locus_tag="PC366_001720"
     CDS             complement(28269..29369)
                     /gene="vanG"
                     /locus_tag="PC366_001720"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HDF2577250.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            complement(29626..30708)
                     /locus_tag="PC366_001721"
     CDS             complement(29626..30708)
                     /locus_tag="PC366_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2577251.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            complement(30758..31459)
                     /gene="vanR"
                     /locus_tag="PC366_001722"
     CDS             complement(30758..31459)
                     /gene="vanR"
                     /locus_tag="PC366_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanR-ABDEGLN family response regulator
                     transcription factor"
                     /protein_id="HDF2577252.1"
                     /translation="MNENILIVDDKKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KDLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            complement(31893..34424)
                     /locus_tag="PC366_001723"
     CDS             complement(31893..34424)
                     /locus_tag="PC366_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2577253.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVKEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            complement(34532..35149)
                     /locus_tag="PC366_001724"
     CDS             complement(34532..35149)
                     /locus_tag="PC366_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDF2577254.1"
                     /translation="MCKKTYLLVVSILIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIITPQQAMEIALKEQNG
                     MVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            complement(35511..36395)
                     /locus_tag="PC366_001725"
     CDS             complement(35511..36395)
                     /locus_tag="PC366_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HDF2577255.1"
                     /translation="MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLVLSKRDIDLTLRRFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAVKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            complement(36586..37836)
                     /locus_tag="PC366_001726"
     CDS             complement(36586..37836)
                     /locus_tag="PC366_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2577256.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLANELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKIQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFIYIIVRDTPKEYGFNVDTEPYEKSEKVNIVDGIKSVIK
                     NKSTWYNSMIMFSFVGLTSAFISLWGVRYIMDVYGVSKSFSAFIVSFFTYGFIFGSII
                     MDFVFAKIRSSKFNIIKFGAMIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDAKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNIVDGYKKGFVV
                     FIVLSIITIVSSHIGVKNDDCKAI"
     gene            complement(38058..38822)
                     /locus_tag="PC366_001727"
     CDS             complement(38058..38822)
                     /locus_tag="PC366_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577257.1"
                     /translation="MLGKLLKYELKASGRIFIPLYIAILIVAVFNGIFMNTNILQVQG
                     IGILVLTSLFMALGVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVLSFIVAVFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILLLVVVMFISYS
                     SFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPNEDTNMVYH
                     LYQSPSFMLAILGSLVVAIALFFATKFILDKKLNLE"
     gene            complement(38816..39541)
                     /locus_tag="PC366_001728"
     CDS             complement(38816..39541)
                     /locus_tag="PC366_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577258.1"
                     /translation="MDKNISNVSQDGIVEFKGVNKSYGTKNVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIDTKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEIIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            complement(39543..39911)
                     /locus_tag="PC366_001729"
     CDS             complement(39543..39911)
                     /locus_tag="PC366_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2577259.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEMLKLITENLKGEL"
     gene            complement(40087..41631)
                     /locus_tag="PC366_001730"
     CDS             complement(40087..41631)
                     /locus_tag="PC366_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF2577260.1"
                     /translation="MRNLQKKLMFFLFICIILQITYTTPVYSLCKLYKNNSINNFESI
                     VSNNQFISKYAIQIILIMAIICMMLIFYIIYDKLNFKIKLQKIAYTDNLTGANTIDKF
                     VIDANKILCKNTQVKYALLYIDIDKFKYINDLFGYEVGNEILRNLTKIIKSNIFEEEM
                     FARISADNFIIIMKYIEEEDITKRLKTIFEELDLFNNNQEEKYKLVLSCGIYFILPED
                     RDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFIIY
                     LQPKIDLNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFERNGFVINLDLYVLEEVCIY
                     LRKWIDAGINPVTVSVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIFDN
                     FDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKRSK
                     IIVTKVIEMAKELGMKVISEGVETEEQFKLLKEVKCDMAQGYLFGKPMPIEEFEHLIV
                     SNLVRG"
BASE COUNT        14023 a         7228 c         4290 g        16199 t
ORIGIN      
        1 tatcttatta taaataatat tattgtttaa actatatctt tattatgcaa aaaataaact
       61 aggagttctt aaaaactcct agtttatttg ataatcattt tacaaaaaat acattttgat
      121 tatatcggat tattaattta ccgcttttga agcatcatct atcattttat ttaaagatgt
      181 tagaccacca tcatttacat accatgttgg tgaatctaaa tatattatat tatcattctt
      241 atatgcatcc atagatttta ttatatcatt gttcaaaaca gattttgcag ttgagctttc
      301 ttttacatca ctaccagtag ctattcctct atctataacg aacataactt ctggattttg
      361 tttagctata tattcaaaag taatattttg tccatgactt gattctttta tatttttatc
      421 tttattttca aatccaaaac tattgtataa tatactaaat cttgattctt caccaaatac
      481 acttaaatta ccttcattta ccattatagt taaagcattt aaatttttat ctgttacttt
      541 tttattcaaa gtttctattt tcttttcaat tttactaaat tcttgatttg ctttttcttc
      601 tactccaaat atttttgcta ttttgtctat attattttta acagattcta agtacttctt
      661 atcatcttta cttgtactta ttgttggtgc tatttttgac aattgttcat aaaaatcttc
      721 ttgtcttcca tttattataa ttaaatctgg atttgccgac tttatacctt ctaaatctgg
      781 ttcttttaaa cctcctaaat ctgcatactt cttatcctta tatttttcta aagatgctgg
      841 taaactcgtt tttggaagtc ctactaaatt ctcagctaca cctaatgcat ccattgtatc
      901 taaagccgaa taatcaaata ctactacttt tttaggattt aattttacat ctgtttctcc
      961 caagttatga gttatcttta tggtattatt tgaattttct gatgtttttg attcattctt
     1021 tttacttcca cctaatgcaa acactgtcac taatcctata atagctactg ctgctactat
     1081 tgctgctttt ttattcatat caatattttc ctctctccta ttaatcttta ttttaattta
     1141 aaaactttat aaaaaatcat atagcaagct tattttcata tacaatattt taaaaataaa
     1201 tacagattcg atttccattt atattcttaa tgttaaaatt catctcataa atatcttcta
     1261 aaactttttc atttactatc tcatctgtac gacctacttt ttcaactttt ccatttttta
     1321 atgcaactat attatctgaa taacatgatg caaaatttat atcatgcatt actaatacta
     1381 tagtcttatc taactcatca caaagacttc taagtacctt catcatctgt acggaatggt
     1441 tcatatccaa attgttcagt ggttcatcaa gtaatatgta ctctgtatct tgagctatta
     1501 ccattgctat ataagctctt tgtctttgac ctccactcaa ttcatctaaa tacttatgtt
     1561 gtatatcagt caacttcata tattctattg cttcatcaat ataattttca tcctctttag
     1621 ttagattacc ttcactatat ggaaatcttc caaatccaac taattctctt attgtaagct
     1681 ttaaagttat attgttagat tgtttaagaa tagctatttt ttttgctaat tctttattgc
     1741 tataattagt caagcttttt ccttctatta ttacttctcc gccatcacct cctataagcc
     1801 ttgtaactat tgatagtact gtactttttc cagctccatt tggtcctata aaagatgtta
     1861 tctttccctt ttctatacta aaagagacat catctacaac atttttattc ttatatcttt
     1921 taaatatatt ttttatctct atcatctatt tgcccccttt aatagtaatt gaataaagta
     1981 aattcctcct ataaaattta ttactacact taaagtcgta tcaaacttaa atacatgttg
     2041 tataaaaaat tgacctatta tcaatgtaat catccctatc aacatagaac ccgaaatcaa
     2101 gtatgtatgc ttatatgttt taaaaatttc tcttgttata ttagcaagta aaagtcctaa
     2161 aaatgtcata ggtccaataa gtgctgttga tattgagact aaaattgcta ttaatattat
     2221 cattttttta actgccttat caaaatctac acctaaatta attgcttgtt ctttacctaa
     2281 cgacaataca tctaaatact ttatttcatc atatataaaa ggtattatgg caataattat
     2341 tataaatgct attaacaata cattagtgtt tatattgttt aaacttgcca ttatactagt
     2401 ttgtaaagct aaaaattcat tcgggtctat cattacttga ataaatgttg ttgcactttt
     2461 aaataaggtt ccaaatatca tacctactag gattaaaaag aaaatattat ttttattttt
     2521 ttcaaataac atcttatata ataacaatga agctccaatc atcatagcta cattaataat
     2581 aaaattataa ttttcattta taatcagact actgcttgaa ccaaatatga atactattat
     2641 agtttgaatc attacataca atgaatctaa acctagtaca cttggtgtta atatttgatt
     2701 gtttgtaatt gtttgaaaca ctacagtagt aaatgctata catcctccac ctaataccat
     2761 agcaaatatt tttggtattc tttgtgataa tgcatattct aaatgattca tgtctattcc
     2821 ataaattata aaaagtgcta ttgatatgaa tagtaatata cttacaaagt aaattttttg
     2881 attgagacta agcttcattc acattcctcc ttaatattaa ataaaggaat agtatacttc
     2941 ctataactcc aactgtaagt cctatagata tttcatatgg ataaataata attcttccaa
     3001 aaatatcaca tataagtaca aataccgctc caagtaaacc agtataccat atgcttgctc
     3061 ttatattatc acccatatac aaggatacga tattgggaac tattagacct ataaaaggga
     3121 tattaccagc tgtaacgact acacatactg taacaagtgc tactattatc agacctatat
     3181 tgacaattct tttgtaacta agacctaagt ttgtcgcaaa atccataccc ataccaacaa
     3241 cagtaaattt atttgcataa atatatgcta atattataag gggtattgtg atatataata
     3301 tctcataatt tcctttaagt atcatagaaa agtcaccttg catccaagaa ctaacatttt
     3361 gactcaaatc gtatttatac gcgataaaat ccgtcataga acctattata tttccaaaca
     3421 ttatacctac taatggtaca aagattatat ttttaaattg taacttccct attattttca
     3481 taaacgtaaa agtccctaca agagaaaata caaatgctat tattgtcttt gtaaaaatag
     3541 aggcagttgg tactaaaagc atacatatta ctatcccaaa ttgagctgca tctattgtag
     3601 cacctgttgt aggtgataca aatttattct tacttatctg ttgcattata agacctgcta
     3661 tgctcattcc tacaccagca atcaatatac ttattaatct tggtacccta ctcatgataa
     3721 atatcataag cttatgctga ttttttgcaa atatatgcat tatatttata tcttcagctc
     3781 ctataaataa agaaaaataa gacaaaatta ttattcctat gactaaatac cttttcttca
     3841 ttctccctcc ttaaaaatct tttattaatt aaaatgaaaa ttattatcat tttcactttt
     3901 atagtttatc aataataatt atcattgtca atatatatct atatctattt ttaacataaa
     3961 aaatgttact agaattgaaa cttctagtaa cattaaaatt taatttaata aattatgaac
     4021 gccaatttaa atatgtagat attattgtat aaatatacta ttttataaat ttaagttctt
     4081 tattatatta ttttagtata tctttaaaga gcctataaaa attaccacta gagattaact
     4141 ctatatcttt ctttttataa cctctatttt caagctctac tactatgttc tgtgctgtat
     4201 gtgtgctttc aagaccatct acacttggca cactagcatt tccagtaaaa gaacctatag
     4261 tctctttccc taagtaatca ctaaaatcaa aaccaaaaga tacatgttct atacctataa
     4321 gatttaccat atagtctata tggtcaacca aatgtattaa atcttgcttc ttaggattac
     4381 tattagtaaa tcctctaaaa ctatttattc caactaatcc acctgtattt gaaatttctt
     4441 ttaattgatt atctgtaaga tttcttttag catcacataa actcctagca ttagaatgag
     4501 aagctataac tggcttactt gcaacagaca ttaaatccca aaatgatttt tcatttaaat
     4561 gtgacacatc tactatcatg cccaattttt ccattttatt gactgctttt ttacctattt
     4621 cagttaaacc acgattttca tcccctaaac atcctgtagc aagttcattc tgttcattcc
     4681 aagttaatga tgcatgtctt gcaccaactt ctttataaaa ataatctagt aaatctatat
     4741 ttcttccaat atggcttaat ccttcaagac caattaaaat atttattttg ttttcactta
     4801 tacctttatc tatatctgaa tattttttta ctatgtttac aacatctttc atatcttcaa
     4861 tttcatcttt tatagagctt ataatttgtt taactctttt ttcaggctct ttatcatatg
     4921 gtgggtctat ccatattaca aaaatagctc cttctatatt tgctctttta aaattatcaa
     4981 gatggattct tctaaataca tctttttccc cgttaagcct tcttattgtt acatctgccc
     5041 aagtatctga atgtccatcg aaaatcataa caacctccaa ttaaataaaa atctttctaa
     5101 aaaacaactt cttttcacgt aaaattatat caaaatattt cctactaaaa gaccaaaata
     5161 attaccaact atgtatccaa atgttccaac tataagtatt ggccctacta gcttagacca
     5221 tccttttgat attgccatag ctgctgctgt tgtaggacca ccaatatttg cattagatgc
     5281 aagaatagct tcttctaaac taaacttaaa tatttttgca actataaatg taactagcat
     5341 gtttattagt accattattc cgcagtataa aagtagtaat ggtgattttt gaattattaa
     5401 tgttattgaa gcaggaacac ctactacaac aaagaatata tatattaaaa atgtacccaa
     5461 ttcctgtgct ccttttatat caccaaagaa attaggcata aatgtggcaa acaacatagt
     5521 caaagtagtt attattagat attgatttcc aaataaagta tttaacattg ctaaaaaagg
     5581 atttgataat ggtattatag ctttaaacca agttgatagt tctacagata ctgcgacaat
     5641 tataaaggcg ctaccaatgg ctattgctat atcttttaaa gatatttctt ttcttcccca
     5701 ataatttgct gctactgttt ctccttcagt tatacctata ctttccattt catctacatg
     5761 tggatgttta aaatgttttc taaaaaatcc aattgatggt atagctatta agacaaagaa
     5821 atataatgcc attaaaagat tatctgctac aactgttgct gatactaatt ctcctggcgc
     5881 atcaaacgcc cctgacatag cagcaaagtt tacatttcca cctatataag aacctgtcat
     5941 catagctgca acaatattta aatctggtac tacatttttt aatgctaaaa atccaatcat
     6001 agctccaagt acagttccta cagaacctac aagaaatata atgagcaatc ttccactttc
     6061 tttccatatc tttttaatat tacattgata taacaataaa gctatggcta aaggaacaac
     6121 atatccccat acttggtcat atacaacaga ctctactggt ataatattta gatttgataa
     6181 taacattgct cctacaagag ctattattgc tcccgacact tttgatgccc aattgtactt
     6241 ttgttccaag taaatactaa atgctgccca tccagttaca actgcccata atacccaaat
     6301 attatcagga cttacaaaac tcttcatctt aattacctcc atttcattaa attaaaatat
     6361 cattatcaat attcaatata ttgaatatta atactattat aatgcatctt ttcagaaaat
     6421 tcaatataac ataaaaaata catgcattat aaaacttttt tttattttat taatctttat
     6481 aaattatatg ttataatcat gtctgagggg gtttgtatct aatgaatata gatgtcggaa
     6541 gcaaaattag atctcttaga aaatctaaaa atataagtat ctctacttta gcaaaaaatt
     6601 cagatttaag tacaggctta ataagtcaaa ttgagcgtaa tatggttgtt ccatctattg
     6661 tagcaatgtg gaaaatatca aaagctcttg atataaatat aggttatttt tttgaagaga
     6721 ttggaagaga ggactctgat atagtagtaa agaaaaataa tcgaaaaaaa atagtaacta
     6781 atgattctac aaaattttat gaacttcttg ttcctaattt atctgggaaa aaaatagaat
     6841 ttatacttgt tacgctagat ggtcatacac aaaaaaacag tgaatttgtg acacacgaag
     6901 gagaagaatg tggctatata ataaaaggta aaatgaagat aacacttgga aataaggaat
     6961 atctattgga ggaaggagat agtttttatt ttaacagtac tataccacat gtgtatgaaa
     7021 attatgatga tgaggtatgt atctcagtct gggcaatgac tccaccttca ttttaacata
     7081 ttgagttctt acttaaatat aaattgataa aaatctgaaa taaattagta tgataaactt
     7141 tactataatt tatttcagat ttttctagtt tattatttat atatcagtca ttatatatta
     7201 agtaggcagt tctcgtctaa aatgttagat aatatctctt cagttccact cattcctttg
     7261 aaagaacttg atataaatga attttctatt tcatttttat ttatatcacc atgcttcaat
     7321 acataggatt tatttgagat attaagcata ccatagtcca taatagaatc tccaactgca
     7381 taaaaatatt ctattcctaa ttctttagtc aagtatttta tagcattttc ttttgaaatt
     7441 tcttttggta taaaatatat ttttctgcca ctcacataaa acttccaatt ttttgattcc
     7501 aatatatttg tatattcttt gattgaatcc aaattaaatc ttgagaaatc aacaactata
     7561 taaaaaaatg tatcttctgc aactttaaaa ttagttattc catctacatt caaatagtct
     7621 ttaaatttat gaatcatact ttcaatgggc tcataatcag gttttagttt atctattttt
     7681 tcactccatg atttcaatat ttcattatct ttaagtataa ctcctccatt tgaagttata
     7741 ctccaaggaa aataaatccc atatttatta aattctatac gcttaaattg ctccactgtt
     7801 ctagtagttg taggtataaa cataccataa tattgtattt gctttattaa atttatagta
     7861 tctaaagata tataagatat ttctttttcc ctataaattt ctatattagc atatttacta
     7921 tcagcattta aaaatttatt ggagtaaatg atactcctgt ctaaatctga aaaaacaatc
     7981 attcaatatt ctcctgtcta atatatttcc taaatatctt tcatattttt tattattcca
     8041 caacatttat aggcttttaa atccatttgt tcaacttcaa catttttctc cttagctaat
     8101 atgaatatat ggtctaaaga tttatcattt aagtctttaa caagaatctt atacggaact
     8161 cttctaagta aaacccttgt cgtttcccct acacctggtt tgataaagtt aatatctgtt
     8221 atgttatact tttcttttat atttaaaaca tcaaagtatc catctcttgt tataatgtca
     8281 ctttcccagt tttcaacttc atcagatata ttcttaaatt gatttttaaa acattcttct
     8341 atagtttcga tatagttcat agattcatct ttatctttta aatgtctata aaacttagct
     8401 ccatgaaagt catttttacc aattaaatcc tctcttagta cagttctact tactaaacca
     8461 gaaacggttg aatttaaaca tgcacttggt attaagaaat cttctctaat tccataaagt
     8521 cctgaatatc cagcagggtc agctaataca gcaagtgttg agtcaaaatg ttttttaaat
     8581 ttaacattaa gttcatcaca tgctttttca agttcttttg atatagttcc cttaccagtc
     8641 catccatcta aaaattgaat ttttgagctc ggatgattct ttactatata ttcaattgca
     8701 ttcatatcta ttcccttatc tcttattata gagattgtat agtgaggtaa acttacatta
     8761 tacttgcttc ttatatatct ttttgccaaa ataccaatag gtgttcctgc tctagcaagt
     8821 gaaactagta ctacatcatt tccatttttt ttaattattt tttcacacat aactcctata
     8881 gaaaatgcaa gcttatcttt attttctctt agtttctcat gatataaatt cagataatct
     8941 tcactaactt catactctat tggtatcatt tctgaataat gtctaccatt ttgtattttt
     9001 aattctcttt ctttatttcc ttcttcttca attaaatttg atatatcttt taataaaaaa
     9061 ataacatcat ctttagaata cgtgctaaaa tctctcatat gactcaactc ctatcttaaa
     9121 atcgtgatat attttatcct gttaaaacac tttagctaca acatactata gttaattctt
     9181 ttatacttgt ttttttaatt atatcaataa attctagata agaattttca cttttattca
     9241 gctctacaaa taaataacac ttagaaaaat tatgtttatc tatattgtaa atataatttt
     9301 gaatatctat attataaaaa ctctttagca taaatttact tttaatagga taatgcttct
     9361 tatcaatatt aataattgga cttcttgttg ttgaatgata gtatatatca tattgatttt
     9421 ctttttcttt tgcaaacagc ataggtatat acataaattc ttcagtacct aaaaatagaa
     9481 tcttttcttt ttcatttttt aaagattctt tactggccat agttattttt ttactttctc
     9541 tcttaacgat ttcttttaat ctaaattgtt ctcttctatt aattccaaat cttcctgtat
     9601 attttacata tttcttattt ccaatataat cttctaaatc aacataaata tgatttacta
     9661 ctaaatttac tttatcactt gaaatagtct ctaatttagt aatactataa ttatcgttgt
     9721 aatttgaaat aatatcttca tctatataaa atttaaagtt tcctttaaat aagtatacaa
     9781 aatctatctt acaatttagc tctctttcta aacgagtaac tttacttaaa ttttcatcac
     9841 ttacccaatt gagtattgag catatagtgt atttcttttt aggataaatg ctttgaattt
     9901 tcctaattat attcatgcat gtattggctg tggtaatctc atcatcaacc aatattatct
     9961 catctccaaa tttaaagttg ttaagcatac caaagtataa attctggtct gttgcatggg
    10021 aatgttcctc taaaaattcc agattttcta actcgtcaaa ctgctctcta gtagtatgaa
    10081 taaattcata atctccacat aagtaatcaa aaaaactatg cccaacagct gtaccagttt
    10141 cagcaaaagc tataacagta ccatttgatt cttccttatt tttttcatta taaattgtag
    10201 ccattaattt tcccaaatta tccatctcac ttggcttaca tgctaaatgt ttaccgagtt
    10261 tctttgagat aaacaaaaaa cgtcttttgc tattatttct tactcctacg tctaaaaaat
    10321 catttagttc taaattcaat ggattatcaa taatgtcaat ctcacaatta aaatttaagc
    10381 aattcttcat agtctactcc tttatttaat acaccatata ttttagatag aatcaatgtt
    10441 tttttagccc ataaaaaatg tggatttgtt tcattcattc tctctcctaa tacacccttg
    10501 ctcacaccat acttactgtc tgtactatcc agtatatcca aagcatcagt aaaatcttca
    10561 tatgatactg tagatagcgc ttgtacaatt tgaatttgca ttggatgaat tacggtcttt
    10621 ccaattaatc catgatattt atccaataat atttcttcta tatacttatt tcttatatcc
    10681 ttatttgtca tatcaaaaaa ttctgatact ccaccactta taggtatatc taactctggt
    10741 ctttgaagat atgtgattat atctaatata aatgaagaac aaatcaaatt attatatata
    10801 gagaagtttt tatctctcct tataccatac atccctaata tatcagttat gcctactcta
    10861 atgcttaata ttcttgactt atgtcttaaa atagcattgt acaaattagt aaaactaagt
    10921 tctttttttt cattatatat aaattctctt gtctctatta ttggaataac atacatatct
    10981 tgaagattca tagaatataa agcttctata caattttcaa tcaactccga atttgcttta
    11041 ggaattaata ttcctgttat agaatgacta tttttaatta taatctcttt aattctcaac
    11101 agttgctcca catcttttat tcttacaaaa attagtggta ttccatcttt attagttata
    11161 ctttcattgc taatattttt taaaattaat ctaagatttt ctatagcctc taactctcca
    11221 tttactccaa cagcatcttc taaacaaata gctaatggtc taactccctt aacatcccct
    11281 ataatactct tataaatcat attatattga gtagctggaa cgtataaaaa agcgcccagt
    11341 gcatatttca acacatcttt ttcagtctta gcactaaagt cttctggctc cttcaaaaaa
    11401 attctctcca aatcatcttt gcagatataa tcgaaatatt tcaatgtcta gcctcctcat
    11461 atacatagaa agggccaact ttatacaaat tagcccttaa tataatacta cttattataa
    11521 attatagtcg tatttaattc ttccaatctc tttgtattat ccttaattaa agctctattg
    11581 ttttcttcta ttctcatagt ttcatctata ccagacttga tagtattgta cattttttcc
    11641 aatgtttcta tttgaacaga acttgttcca gccattctag ctatttgtgc actttgagta
    11701 cttacatttt gtgcatttct aagcaataat tcattagttt tgtcatcaag tgcttttaga
    11761 gattttgctt gtaattcttg ctttttaagt aatatagctt gagataaaca ttgtttaaat
    11821 actggtaaag ttacgacaaa tgcactattt atttttctaa ttaaaccata attattatgt
    11881 tgcatacctc taagcatagg tattgtttgg atagctatat tttctgctat tcttaaatca
    11941 tagactcttt gatttaacat atcataaact tttaatagtt cttgataatt gacaacatcc
    12001 atttggtctc cactagtctc tgatttttgt ttaaagaaag gtagtatttc attatccatt
    12061 tcttctattg ccatttctcc agcaacaata tatttttgaa gttcattata aaactcaaag
    12121 ttttcattta acatagcacc tatttgctta ttagaaagtg ctatatctct ttcgtattgc
    12181 tcaagctcaa tttgaatttt ctcaacttct cctcccaatg tttcatactt ttgaaacatc
    12241 atttcaatgg cattattagc ttttttgaaa agtttttgaa cgaaatttgg ttccttagtt
    12301 tcttgaaaat cgtctaaatc aaacttatcc attattttag ttaaatgaac cagcatttta
    12361 gaattttctt catttctatt taattttatt gtatttaaaa ggctatcaga aactcttgct
    12421 actccttcag atgctttcct accaaactgt aaaatcgtat ctggattttc tacttctata
    12481 agggatgtca atgcctcaac ttccttagac tttctcagtt catttttttt attatttgta
    12541 tattccatta tatcgaagtt ttcttcttga actgctgtag gcaaattctc agtaacctct
    12601 acagagttct tatcttttga aaaactattt atatttatcc ccatctaaaa tcgtctcctc
    12661 tttccaaaaa tttttttaag taaaggtata tcattttcaa gcgaatttaa tttaaggtca
    12721 tataccattt tatccaatct gtgtatatca atcaattggt tatttataac attctctata
    12781 ttgttttctc ctcctggaca taatatgata atatcaaatc caatcttact aagtaaaagc
    12841 ataagaaaaa ctatttcttt atcaaataca atactcttgt acatgtatat aatcaatttt
    12901 gggtttataa gtgagtaatc gaaattgttc atcatatgaa caaatttctt atccatgtga
    12961 agtactgtaa atagaccttt tatcttgtct tctccactta aaccattcaa aaacatactt
    13021 ccttctaaca actcttccac tttctctaaa atcataattt gttgattaag tgctagtgtt
    13081 gatatggaat aatctttatt atttaaaaca gagtttttat ctattacacc ttttgaatcc
    13141 aataaaaagg ataaactaaa agcttctctc gtaaaagctt ttgaaaatct atctacatct
    13201 ccattaaatt caataaatgt tgaactttcc gaatctctta ataaatctaa aaacttaata
    13261 tattcattct tatcattata tattccatta atcttagaaa gaaaatttgg agcttctaca
    13321 atagcatcat taaacttaaa tcctggtctt aatttaagtg gttgattcca gtatattgat
    13381 atttcatcaa cagttgaact tagaagtaga ttttttattt ttctatcttg gagttgccaa
    13441 ggttttataa atcctgcatc atttaacaat tcctcactta tacgctttga tgcttctgcc
    13501 ccaacagtaa aagctttttt tacagaactt ttatctattt tttcccctaa aataaccctt
    13561 tcttcaaaag aaattttttc ttctattatg ttggcttctt caaactctat attgtatctt
    13621 tctgatttta aaatatctat attactcttt gaatttggat taagatataa aacatcaaaa
    13681 cctgccaagt ataatattaa gagtaaataa acttcatgtt tttttatatc tccataaaat
    13741 attacttttg gagcttcatt tttatttata tctaaagcac cgatataaat ttttatccat
    13801 gccattattt tcactataaa attttgttta actctatcat tagtaaattc tttttcctct
    13861 tcttttaaca ctctatccat tgcttgcttt attttataat caatctcttc aaatcccaaa
    13921 atatttatat ctacatcttc catgctagtt ctatattttt gaagtccact tttaaaataa
    13981 tttataatat caaaatcact aggatttgct ataacatcag taaataaagc aatatctttt
    14041 ttgctatcaa tattttgttt tgtcttaaat atctcgagat tgtacaaaac ttcatcttct
    14101 aaaccaatat acgaaataaa ataacttaga tatccctttg aaggagtgta atttcctcta
    14161 tctgattggc tggagaatat tttttcaaat acctttgagt cacccataac tatcctccca
    14221 atttaaatgt ttattcagaa ctgacccaaa attcatattt tgagtcagtc tgttttcttc
    14281 taaaaaattt gttttaagca gtcttttttg gttttaccag tcttattata cattttacaa
    14341 cttcattaac cacaattaca cttgctgcta cacataaaac ttttacccat gtcataaaat
    14401 ccattgctac agagttaaag aaatcttgga atagctgagt aaatattact tgtgcaattc
    14461 ctgtcaacac tattatttgt agtgctaatt tgttatgtgt aaaattaggg aagatactat
    14521 ctgcattaaa ctctctacag ttaaatgcat taaacagtgc gctaaaagca aataacgcaa
    14581 acattactgt tcccttatga gcttcatcaa ctcctaagaa attaaatgta gattgtaaca
    14641 ttagtattgc tgttatataa aatgcattta atactattgt atacaccatt gacttagaaa
    14701 ttatattggc ttttctatca acaggttttc tatttaacac atggtctcta actggctcta
    14761 aacctaatgc tagtgctggt ggtccatcca taattatgtt tacccataat aattgtattg
    14821 tagtaaatgg catctcttgt cccataactt gagatattat agccactaaa aatgcaatta
    14881 catttacagt taattggaat tgaacgaatc tttggaagtt atcataaatt cctctacccc
    14941 atttaatacc ttttacaatg gtactaaaac tatcatcagt taaaattatg tctgctgcgt
    15001 ttttagatac ctctgtacca gatataccca ttgctatacc aacatctgct tttgaaagtg
    15061 ctggagcatc atttatacca tcacctgtta ctgcaacaac atccccgctc ttttgcagag
    15121 ctgaaactat tctcatttta ctatctggtt tacttcttgc cacgattgaa atactttgta
    15181 tctcttgttt taattcttca tcatctaaag tatctatata tgaagcttca accactctca
    15241 tattattttt taataggcct aactcttcac ctatagctct tgccgtattt atattatctc
    15301 ctgtaagcat ttttacagaa acaccagctt tatttgctgt atttacagac tctataacat
    15361 cttttctaag tgggtctctt ataccaacaa aaccactaaa tactaaatta ttttccattg
    15421 cacttacatt catagcatca ctttcagcag ttactgctgc ttcttcttca gcttgtgaga
    15481 tttctttata tgcaaaccct aaagttctca ttgattttat ttgcaatttc tttatttctt
    15541 ctaaaatctc atgttttata ttttcagtta atggaactat gtcttttcct ctttgaatat
    15601 gtgaacataa ttcaagtaag acttctggtg ctccttttga taatagtaca tgatgattat
    15661 cttgacctat aacagaagtc attctctttg aatctgaagt aaaaggattt tgagctacta
    15721 tattagaatt ttttctaact tgtctataat ctacgttttt gtaatataaa agcaatgcac
    15781 attcagtagc acttcctaaa tacttaatat caccatcatt gtgctctaca tcagctgtag
    15841 agtttatcat acagttttct tcaaaataac tatttatttc ctcttctgaa ctttcaatat
    15901 atctgccatc aacatatgca acttctacag tcattctatt ttcagttaat gtaccagttt
    15961 tatctgaaca tattacagaa acagaaccta tcgtttcaca agcttctttt ttggtaacca
    16021 atgcatttat tttagccatt ttttgcattg ttattgcaag tgtcatattt atcatagttg
    16081 gaagaccttc tggcactgct gcaactatca acgcaacaca tactgtaaat gctgttttaa
    16141 ctgggtctat tgattctaaa aacggtaata ttccagacat atctacattt aatacattct
    16201 tacttatcat ttggaaaacc ataaatataa atagtaatcc tgctactgca ctagaaactt
    16261 tggctatcaa accacctaaa tttccaagtt ttatctgaag tggagtttgc tcatctgttt
    16321 ctgataagtt ttgagcaatt ttacccattt cactattatc tccaattgaa gttacaacta
    16381 gagctcctct accataagct acaagtgtac caccaaacac catatttatc tgttttgcag
    16441 gtattggctc ctgtactact actgctcctt tagattctat ctcttccata gaaactacta
    16501 catcacactt tttagatacg tcatcagatt ctcctgttaa catatcttct ctaattttaa
    16561 ggtttatact ttctataagt ctaccatcag caggtaccat gtcaccagtt tcaatatata
    16621 ctatatcacc tggtaccaat tcactcttag aaatttgatg tacttcccca tctctcaata
    16681 cttttacttc tatgttttca gtcaacttag aaagagcctc tgctgctttc ttagaacgac
    16741 cttctgtaat catacctatt gctataccta ttgctatagc acctacaatc cctattgcat
    16801 catgagtttc cccaattact gcacttacta ctgctgcaat aatcaagata actatcattg
    16861 gttcacttaa actttctttt aaatcatccc aaaaactacc ctcttctttt ggagtaaatt
    16921 cattcaaacc atatttttct cttctagtct tgacttctga ttctgataaa cctttttcag
    16981 gattaacaga taagtctttt gtaacttctt ctttatctac attataatat ttgatatcat
    17041 tattaaattc catatgcaca ctcaatcctg tctaaatttt gcattacttc tttaagaccc
    17101 gcatcttttg ttccttcacc aattgcttta aattgccaac ttccatcttt tctatatata
    17161 gctcctacta taagagtagt tttttcagaa taattatcag atagattgta ttttgctatc
    17221 tctttcttat taccttggtc ttcaactctt atataggcat tttctatcat tccaaagtgt
    17281 tgttttctat ctacacaatt gtatatattt actacaaaca ataatttatg aatatttgat
    17341 ggaactttat ccaaattaac taggatttgt tcatcatcac ctgtaccctc accagttaga
    17401 ttgtctcctg tatgcaaaac tgatttacag gcacttttta gatttccaaa ataaattaaa
    17461 tcttttattc cacttaattt accttcttga ttaagcataa atacagatgc atcacaatct
    17521 atatcagctt gtcctccacc aaataacgat ttaaaaaaac ctcctccaga ttgttgcaca
    17581 gggtcccatc ctagacctac aagtatgtta ctcagtcctg ggttagattt ttttaaatct
    17641 attttatcac cttttgataa attaatcgac atactaaacc tccacaaaat tttatataat
    17701 ataacctata cattatttgt ataggttatt tatatttaat atattatatt gcttaaatta
    17761 aacatttaag ccatagtttc tacaaagtgc ttctaagcca ccttcaaatc ctgctccaac
    17821 tgcactaaac ttccattctc cattatactt atatatctca catactgtaa ttgcagtttc
    17881 tatactaaat tcttcaccta agtcatatct taatatttct tcatcatttt cagaatttaa
    17941 tactcttata tatgagttgc ttacttgtcc aaaattttgt cttctttcag cagcctcata
    18001 tattgtaact gttacagcta tcttttgtat atgctttggc attgtctcta aattcactaa
    18061 tatttcctca tcatctccat caccttcacc agttctatta tcacctaagt gttcaactgc
    18121 tccagatgga tgtcttaagt tattgtagaa tataaaatct tcatcttttt caactctttg
    18181 agattctcca accatgaaaa cacttacatc taaatcataa tcatagccac tatcaaatga
    18241 atttgtatcc catcctagtc caagttttat atttttaaga cctggatttc ccttagttaa
    18301 atcgattttt tgtccttttt ttaatactat agccatggaa aatatccccc tttagtttat
    18361 tgttatagtt gaaattataa gtttattcca aagtttccac ataatgcagc aagaccacct
    18421 tcaaaaccag aacctagtgc attaaacttc cattctccat tgtgcttata tatttcagct
    18481 actactatag ctgtttctat actaaaatct tctcctaatt catactttat taactcttca
    18541 tttgtgtctt tatctactat tcttatataa gaattactta cttgtccaaa attttgtctt
    18601 ctttctgtcg catcatgaat tgtaacagta aaagaaatct tgcttatttc tccaggaatc
    18661 ttagataaat caacaactat ttgttcatca tctccatcac cttcgccagt tctgttatct
    18721 cctagatgct caactgctcc agatgtatgt tttaaattgt tgtaaaatac aaaatctcca
    18781 tcattagtaa cacttccact tgctcctgtt aaaaatgctg ctgtatctaa atcaaagtca
    18841 aatccaccat catacttgtt agtatcccat cctaaaccta ctaaaatatt tttaagacct
    18901 ggatttcctt tagttaaatc aaccttttgg ccttttgata atgttatacc cataatttat
    18961 cgctcccttg ttaattttag ctaaacaaat cttgctaatt atttatcttt ttctttaatc
    19021 atattataac attttttatt catttgtgaa gaaaacttgc ttgatatttt taaaatataa
    19081 ttaaaaaaat gtttatattt cttacttttt acatagattt tacatacttt attaaatgta
    19141 taaaagctat gtttaatatg taattatata tcatttatat aaacaagtac atattttatt
    19201 ttgaaactac aaaattattg tactatattg ttttaagttg ttttataata gattatatca
    19261 tcttattata ggagaaaaaa tatgatttgt actattaaac cattaaagat ttcaataaaa
    19321 aagtcaactg aacctctaat tgaatttata tctgatacta cctataaaaa taagagttct
    19381 tcatatatta aagaagtcca ctttacaaga tatataggtg ttgatgattc aattgataaa
    19441 tacatagaaa aagttaaaaa tatagatact tattttttta ataatcctac aattccctat
    19501 attagattaa acaatctaaa aataaatttt gacaaagaac aaacagataa gatgcttaaa
    19561 atttttaata tttatgatag ttctaagttt aacagttggg atttatataa tatcgacttt
    19621 ccatgtaaaa tagaaaatga cactttaaat tggactaaaa agattgcatt taaaaatact
    19681 ttagatttat tttccacaag tatgccaaat tgtacatcct ctatcatcaa aaactttgca
    19741 gttaaacttt tgtgttggat ggactatttt ctacctaaat tattttataa caaggtgaag
    19801 actactattt caccaaagat agtatacttt ggaaatatta aaaggcaaga actttttttc
    19861 ttatattttt tatcacaact tgggtgtgat attttatata taaatccaaa taaagatatt
    19921 cttgatttat atcctgaatg ttcaaaattt tctactctat ttgaactttc taggaaaact
    19981 ccaaatatat tagaaatacc ttttgaaagg catattacaa atataaatta cagtgaaaat
    20041 accaataaga cttctcctac tacgaataaa cctaactcta aaaatacact taataacaca
    20101 aatctaacat ctaaaaaaat tgcacaagat gaggaagtag aactttctta tgaagacctt
    20161 gcaaagttat cagcttctgt tgttatgatt gttgtgtgca ataacgaaaa taaaccgttt
    20221 aagagtggtt ctggagtagt aataaataat gaaggttata tacttacgaa tcttcatgta
    20281 gtcaatgatg ggtattcatt tttagttaga tttgaaaatg atgataaagt ttatacatct
    20341 taccaaatta taaaatacca ttcagattat gatttagctg tgataaaggt tgatagaaaa
    20401 tgcaaaccaa tacctgttaa agtcagtaaa aaacctgtga gaggtcaaaa aatagttgca
    20461 attggaagcc ctttaggtct ttttaataca gtttcagatg gaattatctc agcttttcgt
    20521 gattttgaaa cggttcaaat gatacaattt acagctccaa tctctagtgg tagttcagga
    20581 ggagctcttt tagatatgtt tggaaactta ctaggattga tttccgctgg atatgatgat
    20641 ggacaaaact taaatttagc tgttgaaagt aatcttgtca aaatatttgc caataatttt
    20701 attgagatag taaactaatc aatcaaaatt ctacttatcc tattccataa taatcaagag
    20761 ggtgaaaaca ttgcatgctt ttgccctctg attaatattg aaaaaagtat taatactcga
    20821 catttttatg ctcaataaat aattgatgcc atagacaaaa tgtaaatata gtccatattt
    20881 ttctcgaatt atctctatga cctttaagat gcgtatctaa aagttttatt gcatattttt
    20941 tatctataaa ttcatctaca tttgaattat aaatagtttc ctttacaata tcccctagag
    21001 aatcttttaa ccaaactctt attggagttg gaaatcctaa ttttttcctt tgaacaacat
    21061 attctgggac tatttctcta aacgcctctc taagtaaaac ttttgtatta ttcttattta
    21121 ttttttgctc cattcttaaa ttttttgcta catcaaatac atctttatat aaaaatggta
    21181 ctctaagttc aacctgctca gctgtagaaa gtttgctaat tttttgaagt atatcgcctt
    21241 gaagccatgt attcacatct atatgttgca ttttacttat ataatcgtaa ttattttttt
    21301 gtgcatctct atacaaatta gacaacaggt attcatatat attcttttcc ttatacttaa
    21361 aaaagaatct ttttacttcg ctgttttcaa aaacttttgc atttcctata tatctttttt
    21421 ctaatggtgt tgtagctcta taaagataat ttcttccttt tatgtttggc ataagttctg
    21481 aaactcttcc taatatactt ttaatataag taggtgaatt gacaactgat ttcatagtac
    21541 tatactcttt atatatatta tatcctccaa ataattcatc tgctccttct ccagacaatg
    21601 ctactttaac atgtttacct gcctctttaa ttaagaaata aagacctact tctgaagggt
    21661 ctgctatagg gtcatccaaa gaataaatta cattcggtaa tgattttata tattcatctt
    21721 gtgttatatt aatctggata ttttctatac ctaacttatc agctgttttc tttgctactt
    21781 ctaattcact atatcctttg acactaaagc ctgcagaaaa agattttata tttggattaa
    21841 tttgtgaagc cacagtagtt ataatagatg aatctattcc accagacaaa aatgttccaa
    21901 tttctttctc ctcttccata tgagttacta ttgaatctac tactatattt cttatatcat
    21961 cctcattcac atctctattg cctaagtgat ttttagtata aaaaaatttt gtactacttc
    22021 taaactcaag tttattatat ctctttaaag atagtatacc attttctacc ctaaaatagt
    22081 gacctgctgg tatcagcctt attccttgta tcatagtatc ttcaggaagt acatattgaa
    22141 atgaaaaata actttgtaag cttctttcat ttatatttaa atttttcata tattcaagta
    22201 aaaacttata ctctgaggaa aaaattattg cattttcctt atttatataa taaagtggtt
    22261 ttatcccaaa taaatctctt gctccaaata tactttcatt ttctctatca tagattataa
    22321 agttgaacat tcctttaatc ttatgtacac aattcttacc aaattctata taagatgcca
    22381 ataagacttc aatatcatca tttgtagtaa aattgtgtcc ttttttaatt aattcttctt
    22441 ttatttcatg atagttatat atatttccat taaaaacaat aacttttcca tctttttcaa
    22501 atggtttatt tccataaata gcatcaatta cattaaatct ttcaaaatca aaagtttttt
    22561 cctcatcctt atactctatt ctactagaaa gtcttgtatt atttacagat tcttttattt
    22621 taaatttaat atcttctttt ttagatatat cacctttata ataaattgaa atattgccgt
    22681 ccatataatc aaaattcctt tctgtccttt agtcttattc tatatttcat agttttgtct
    22741 ttggctttaa aacttattca atttaaaatg aaattgctat taaattctta taaattatct
    22801 gttaatattt catatttttt ttatttctag aaatactata ttaggaggtg atttttatga
    22861 agaaaaaaat attaatacca gttattatgt ctttatttat aatctcacag tgcataactt
    22921 catttgcttt tacacctgaa aataacaaat ttaaggttaa accattacct tatgcatatg
    22981 atgcacttga accttatata gataaagaaa caatgaaact gcatcatgat aagcattatc
    23041 aagcttatgt tgataaatta aatgctgctc ttgaaaaata tcctgagctt tataattatt
    23101 ctttatgtga attattgcaa aatttagatt ctttacctaa agatattgct acaactgtaa
    23161 gaaataatgc aggtggagct tataatcata aattcttttt tgatataatg acgccagaaa
    23221 aaaccatacc ttctgaatct ttaaaagaag ctattgatag agactttggt tcttttgaaa
    23281 aatttaagca agagttccaa aaatctgctt tagatgtctt tggttctggt tgggcttggc
    23341 ttgtagctac taaagatggg aaattatcta ttatgactac tccaaatcag gatagccctg
    23401 taagtaaaaa cctaactcct ataataggac ttgatgtttg ggagcatgct tactatttaa
    23461 aatatcaaaa tagaagaaat gaatacattg acaactggtt taatgtagta aattggaatg
    23521 gtgctttaga aaattacaaa aatttaaaat ctcaagatta attaaatatt aaaatccttt
    23581 tgaaaaaaac ttatgtttgc tatataatat aataaaagat agtctaaatt taccaatata
    23641 atgtttatag tgacgattca ggaggatttt tatatgataa aagaaacaca tgaaagggga
    23701 ggttatatat tcgcactttt gatactcccc tttataaaca atctgtacct agttaaatac
    23761 gatattgcat ataaaatagt attaattata atttatattt attttgcata tttaggttct
    23821 ttatttccag atatagatat gagaggttct tacataagta aaaaatttat gttaatatac
    23881 aaattatttg gaagtaggtt tagacataga gggtttactc acagtctaat tgccttatta
    23941 cttatttata gtttttttaa atctctgaca atcttcacta acaataatat agttttctca
    24001 tgtttgtcca gtgggtttat aataggatat ctatctcact tgtgtcttga ccttattact
    24061 aaagaaggta ttgaattgtt ttatcccatt accataaaca tttctttact acctataaaa
    24121 actaactcaa aaacagaaaa attcatatct aagctattaa atttcatagt tatttttttg
    24181 attggatatc aattttatat tttattatag ttgtagaaaa aataaataac aatattttga
    24241 actaagtata aataagtttt atatatttta gtttacaaaa gaactaaaaa ttttgtacct
    24301 taatacaaaa aataaaacgt atcttaaaat aatttagtac taaatcattt taagatacgt
    24361 tttatttcgt acaagctaaa tcattttatc atctttatca ttgtgatgtt ttttatgatg
    24421 gaaatcataa ttatgatttt caagattttt atttactcta tttccaatct tccatgacaa
    24481 aaacaccaat aatataaatg atgctatctt taaaggactt gttataaaac cttctatatc
    24541 acttgccacg taacttataa ctataaacat tacaaatttt cctgccaaca ttgctggcac
    24601 aaaatctttt aaatcttttt taccaaaagc tgatgcgata gtaactaaac aaccaggcat
    24661 aaatggacag gcatacgcta taaataataa cttaaatccc tgtttatcca tccaacttat
    24721 tgctttttca gttttactat ttctcaactt attaaaaagc ttactatcat taaatctgct
    24781 tattaataag aataatgaag ttgtcccaag tcctgagcca atccatgata acaaacatcc
    24841 aataaataat ccttgtattg cagcatttgc tgtaactata gcaacaagtg gtaaggctgg
    24901 tataaagctt tctataaatg cacttaataa gccgattatt gtggctaaca cccaataatt
    24961 ttgagtcaaa tcaagtaatt cttgtatata ctgcatattg cttttcccct tttttaactt
    25021 taactattat tatatactct atatgtttat tatataccaa tctcaaaaaa tgaatctaat
    25081 attaaaaagt aaataatcta tataagttta cagttaaggt ataattattt tattatatat
    25141 tataacaaaa aaggtgatgt ttcaaaataa aaatctgaaa catcaccttt ttataactta
    25201 aattgtcatg taagttataa aaaatatata ttagacataa tattactaaa aatgtctagt
    25261 cagagtaaaa taaattacac agtacaacaa atattactat ttaattgagt tacttcttta
    25321 taacatttaa ccttcttcct actctgctca ataattcatt cgatatacta catgagttat
    25381 ttgcaacttc agaagcagat aattcagata aattatctct tcctattatt attgccgtat
    25441 taccaacttc tacattaggt atatctgtaa tatcaacagc aagttggtcc atgcaaattc
    25501 gacccactat tgctgctcta caaccattta ttattacgta actttttcca caggataaat
    25561 ttctaggtat accatcggca tagccaatag ataatatagc aattacgcta tctctgcttg
    25621 caataaagac tcttccatat ccaaaactat catctttttg tatttttcta ataagaatta
    25681 cttgtgattt taaggataaa acaggtcgta aatcaagttg caatttagtc gtatcatttg
    25741 gagaacttaa tatcccgtat aatgcaattc caattcttac ataattacac ttaagattgg
    25801 gataattaaa aaaaccataa ctactttgaa tatgtacttt aggaattttt ataccttttt
    25861 ttaacagaaa atcaattaac ttataaaaac attcaatttg tttatttgta aagtctacat
    25921 cttcatcttt cagactatct gaaacacaca agtgtgtaaa tatgccacat atatctaagt
    25981 attttaattt aaatgccttt aaaattgacc tcacatcatt aacatcaaaa cccagtctgt
    26041 gcatacctgt atcaatttta atgtgtgatt ttatgttgta tttctgtttg tttaaagaga
    26101 tagcatgatt aaggtcaata acactctgtg taagattgta tttatgaagt tcctttgccc
    26161 ttattgggtt agtatatcca agaatcaata tttctcctag tattccatat cgacgtaaat
    26221 caatcccctc atctattgtt gctactgcaa atgcttttac acctatttgg tttgcacaag
    26281 tcgctacttc aaaagcacta tgaccatagg cattagcttt tacaactgcc atcaattcac
    26341 aatcttctgg catagctttt tgtatcatct ttacattatg ttccaaatta tttaaatcaa
    26401 tttcaatcca agctctattg gtatttacct tatgttctcc tttcaagtct ttttttagag
    26461 gtttaagaat caatataata attatagaag ctataaaaga tgctatactt accactatat
    26521 aatgaataag gctattgtca accaagacag tttgtattcc gaatatttta gaaaacatac
    26581 gaataacaac aatcatcata ggatgtataa tataaataat taatgatgat gttcgcaata
    26641 acctagctcg agaacctttt aaaaatgtta aggctgtaaa taagaaatac atacatggca
    26701 ataacataat atacatgcta tcatgacgct gtacccctag tttatgtaaa aacattccct
    26761 cacataacat aagtaagaat gatataagaa atccaatcaa gctattttta gttgacatat
    26821 aattagattt attagatatt attccaccaa gtatgaaaaa tacaggtgca aaaaatatac
    26881 catttcgtgt ataatctgat acttcaaaaa tatacccata taaattcttt aatagtggta
    26941 ttttttctaa aaaaccataa taactatcac caaacatacc aattacataa ataacaatag
    27001 tgattactaa tgagtacttt aaacctagtt tttttacaag aaagtatgca atacttgcac
    27061 caataattga tgcaggtaga taccataaat gatataaagt cccatcaaat acaatgtcct
    27121 taataatatt gggcactaaa ttattcatgg aaaaatatcc agtgtaaata tttaagggaa
    27181 tataaattac aatagctatc ccgtaaataa ataatacatt ttttagaaaa gatttcagtt
    27241 tattacaatt ataattatat gttgaaatta gaaaaaagcc tgatagcata aaaaagaatg
    27301 gcacagcaat acgagcaatt atactagtta acacaaagtc agccatttta ctatatgata
    27361 ataatggaga tgtatgaatt gcaattataa gtaatgcagc tataatccta aaataatcaa
    27421 gccctgcata agatttattc ctaatcattc ttgttcctcc atttcttagt cctttctatt
    27481 tctccaaaat gtcacaataa aaccatcctt attgttaccc gatatttgat atacacattg
    27541 ttcaggtata gagattctca cttcttcttt agtatgaata ggcacataaa agatttctat
    27601 aattttttct ttatcttcta tttttaaaca atttgtatac gaaaatctct taatatattc
    27661 tatatattct tcaagggcga gattcatttt attgataatc tcagaatgtg gatatccgac
    27721 ataacgaaaa tgccatggtt cttgagatat tcctgttatt tcttcttttt tacactgata
    27781 acgctctata aaaccataat gtagtgctgc cttacggaac tcattacaaa taccattata
    27841 aggaaattca gggcagataa aatctataac ctctttcttc aaccctaaat caatagcaag
    27901 ccctgtctga tgttcactgt gatttggaag tgctacaaac tttttagtaa agtcttttcc
    27961 attgtcacgc agagagcttg aatatatatc ttgttgttcc tctgcagtac gatatccact
    28021 tacaggtact atttcattta ttccacatat actttttaaa atattttgta aaatatttgt
    28081 agcttcacgt ttcataagaa tacttggaaa ccttgtatct acaggaatta aatctatatc
    28141 ttcagatgtt ttaactggta aaaaagcatt tactagaatt agattcccat cataaacttt
    28201 atctttagtc aataagatag tatttgtcat tttatcttct ttatttttat ctaataaaat
    28261 attattcatc attttatgta cacctcaatt atcttatcca atatttcttc aaaagacagt
    28321 ccaatacctt tcatcatatt cggataacga ctatgagaag taaagccagg aattgtattg
    28381 acttcattaa aaataatttc accagatgga gttaaaaaca tatctactct agcaaatcca
    28441 gaacatccaa gagttctata aataattttt gctgtctctt gtattctttt ctcacaatcc
    28501 aaatcaattc tagctggcat atgaattttt gaacttttca atgtatattt ttctgtataa
    28561 tcaaaaaatc cttttgacaa ttctatttca tctactcttc caacaagtaa gtcatcgttt
    28621 cctaaaactg cacaccctac ctcaaaacca tcaatatttt cctcaattat tacttcatta
    28681 tcatgttcaa aagccaagtc tactgctact tgtaactctt cttttttata aattttacta
    28741 ataccaaatg atgaacctgc acgcacaggt tttataaata atggataagt taagtctttt
    28801 gacagttcag ccacattaaa tttatctgag tattttagta atattgattt tggtacttta
    28861 ataccttctg aatgaacaag tttatgtgat ttgtctttgt ccatacataa tgctgaagaa
    28921 agagtaccac atccaataac ctgtatacct gccaattcaa ataacccctg cactgttcca
    28981 tcttctccat tttttccatg caatacagga aatacaaaat caagtttagt gtatttaata
    29041 tcattttcac atgattcaat agcactattt ggaatatgat tctgagaaac agcatcagga
    29101 attaaaaatt caataatacc atttttgaca cggttctgcg aaacaataac tggaattata
    29161 tcagtatccc tttcaaacca agtgttattc tggatattat tataatctcc aatataatga
    29221 taccaattac cctcccttgt aattccaatt ggtataatat catatttttc cgtattcaaa
    29281 ttctcaagta ctgcaaaagc tgattgtaat gatacatcat attctgttga gtttccacca
    29341 aatataactg caattttttt attattcatc tttgattctc ctttgttgat ttatttattt
    29401 ttatacaatc tacagaaaca tgttaaaata ctttttctat ttcaaatcca atcaaccttc
    29461 acttacaatt gcatctgttc cacataatat attttcacat ttttctattg atataattac
    29521 tgtatcaaaa taaaagcact cttgttttga tacagtaatt atatcaataa caagagtgct
    29581 ctttatttat cctaaagaat ttcctatttt tttatactta aattcttaca aatttcctac
    29641 aatcggaata ataaccttaa aggtaattat attgttctcg ctatgagctg ttattgtccc
    29701 gttatgaagc tccactattt ctttagctat agcaagtccc aacccagctc taccactgtt
    29761 tgaattacga gatgtatcca acctgtaaaa ttgttcaaaa atacgctcaa gtttttcctc
    29821 tggaatcgta ttgctatgat ttataaattt aagctttata taatcatcct cctgtacagc
    29881 tgttatttca atagtagtat cttcaaaact ataataaaca gcatttcgta ataagttatc
    29941 aaatacacgt tgcattttat taacatcaca ccttatcatc atatttggtg taacattcag
    30001 tgtatatttt aaattcttac tcatcaaagt aggtttaaac tcatatgtta gttgttcaag
    30061 catacgagtt aagcttactg tactgtattc aagtgatata tttgataaat taaaccttgt
    30121 aatttcaaag aattcattaa ttaaatcttc aagacgctct gccttatcca acgaaataga
    30181 taaatatttt tttcgcagtt cttcagaaat ctgactttca tctcgaagta gtgtcagata
    30241 ccctataact gatgtaagtg gtgtttttaa atcatgtgca agataaacaa taagttcatt
    30301 cttacgttgt tctgccattt gtgtctcaaa tttacgttgt tcaagtatat gtttaattga
    30361 gtttattttc ttttctattg ccaataactc tggagataaa gccacttctc caacatcttc
    30421 tttgataaga gagtcaatac cttgatttat ttcactaaaa tattttgtaa accaatttaa
    30481 ataaacacgg aatattataa aaaacacaat caccatagct agtatcatga agagctccat
    30541 gctattacgg aaaatctgct gatataaatt caatgcagct ttatattcca tacgaaaagc
    30601 attttcaaag aatgatacta tccagataga aaacttacca tacaatataa aagaatataa
    30661 aatccatatg aaaataatgg ctataaatgc cattaaagct gttctcataa aaattttatt
    30721 tctcacttga gtaaagtcag gattgacttt aatattttta cttttcaatt gtataaccta
    30781 ctccccatac agtttttata aatttcgggt ttttagaagg ttcatgaatt ttttcacgta
    30841 atcgccctat atgagccata actgtgttat tattatcaag atatttttct ccccatacag
    30901 cttcaaacaa ttcttcagaa ggaaccactt ttccttgatg ttcacataaa taccaaagaa
    30961 tagaaaattc aatcggtgtt aatgctactt ctttcccaaa taaactacat ttatgtgttt
    31021 ctttattgat aatcaatcct ttaatatcat actcattaac aattatcgac tgttgttcat
    31081 aagaattatt atatcgcata tatcttctta attgtgtctt tactcttgca acaacttcca
    31141 aagggttaaa tggctttgtt atataatcat cagcacctat ggttaaaccc attatcttgt
    31201 ctatatcttc aattttagct gttaacataa tgataggata atagtatttt tctcgaattt
    31261 tctggcaaat atgaaatcca tcaatatcag gaagcataat atctaaaata gccatatcca
    31321 aatctttaga ttcaatacat tctagagctt ccttacctgt ataaaacttg tatactgtaa
    31381 aaccttcatt ttttaaatat acttcaatta aatctgctat ttctttttta tcatccacaa
    31441 tcaaaatatt ttcgttcata gattattttt cactctcctt attatcgagg tcatcattta
    31501 taatattggt aaatttacat atcaaataat tacaagcata tttgtaacta atttttataa
    31561 gaaaagaact actacatcag aatgtgttga tgctactatt ggaacacaaa aactgagatt
    31621 aattgttatt ataaaaactc ccctaacacg tccttattat cgcataacag gtattaactt
    31681 tcaataaaaa tatctatcag tcaaacacaa ttcaatttat tataccagag acaatccata
    31741 taaaaaacaa ttaaacctat gtatgtaacc acagacatta ctaaaatttc catgttattt
    31801 tatataaaaa ttcaaaaaag gagttgaatt taaaatttga ttagaaaaaa atcaattttg
    31861 agacaactcc tttttatttt aatgtattta aattatagta tatcagcctt cataatatcc
    31921 tcaaaatcac ctttttcaga tattaatctt atcaatttaa cagtacagct taaatcattt
    31981 ataagtatag ctccaactaa tgaaccatct ttcataaata attttttata tattctttga
    32041 ccttcatctt ttgatgaaat ttctttatca aaattttgta tattaccaat actaaatact
    32101 tttacattca ttgcatctaa tgaaactgga tatacttcac tttcaaatgt caaattatct
    32161 ccacttgcat ttgctcctgc tatttttccc atttctactg aagatggcca tattgctaaa
    32221 ctaatatttc ccacttgtgc aacatctcca caagcatata tatctttaac atttgtctgt
    32281 aatgtcttat ctacaacaat acctctatca atttttacag atgtatcctg aaccatttga
    32341 gtgtttgctc ttacaccaat tgaaaatact accatatcac agtcaacact atctccatct
    32401 ttaaatacaa ctttttgagc ttttccatca ccttcaatac catcaactgc tacacccaat
    32461 cttacatcta ttcctgtatc tcttacacat tgttctaata ttttactacc ctctttatca
    32521 agttgttttg atagtatgct atccatggct tcaactacta ctacttctaa tccttttagt
    32581 ctaaattccc atgcagcttc aagtcccaat aaaccgccac caatcactac aactttctta
    32641 gatttttcta gtgcttcttt tacactatat aaatctttta tatttctaag agtaaacaca
    32701 ttttctaaat catggccctt aatcggtggt ataaagtttc tacttcctgt agctattaca
    32761 agcttatcaa atttaatagc tccatcattc actataatag ttttattcac ttcatctaat
    32821 ttatctacat tcgttcctaa tattactact atattatttt tatcatacca atctttatct
    32881 tccatgtaga aatctgaacc aagttcttca tttataccat cagaaagtgc aggtctatag
    32941 taagtcaact catcttcatt agaaatcata gttatcttac aagttttatt tctttttctt
    33001 atagcatctg ctgcataaaa accagctgct ccatttccta ctattacgaa atattcatca
    33061 gtatcttttc taaaagtaac ttcatcttct tcaacttcta taaattggtc ttccttagct
    33121 ccacatacag ggcatacact aggagcacta tcaccttcaa aaacttcatt acaaattaca
    33181 catttaaatt tcttagtttt ctttttactt ccaaaagtag aatttaactt atctaggaat
    33241 ttacctgtat aagaatgtaa tttatcaatc tcttcatttg atggtttaaa gttaacagca
    33301 aaaggtttta ctgctgtcat tctaagctga cttattctct ccatagcatt ttctatacct
    33361 tctccactcc atccatatga accaaatact gaagcaactt ttccaccatg aagaactggg
    33421 tttaacgata ttaatatatc ccatataggc tttaacgcat ctcctaatat tgttggtgtt
    33481 ccaaataata caccttgtga tactgctatt tttgccaaaa tatcttcttg cttatgctct
    33541 attacatcaa ataaatttac tttatagttg ctattttttt caatatatgc ttttatagct
    33601 tctgccataa tctttgtata tccatgtgca gaaacataac aaattgtaac ttctttttct
    33661 aactttattt gttcctttac actccagtta taataaaggt ctataatttt tctaggattt
    33721 tcagttaata ctggaccatg acctggacat acagtatcta tatctaaatc ttttatcttt
    33781 tctatagcag ttaccataga tggtttaaat ggacccatta tacaatcata atagtatctt
    33841 aaagcatcca agtaatcctt ttcttcattt tcatcaagtg tatttactat cttatcatta
    33901 ctatagtgac taccaaatga atcacatgtt acaagagttt tatcctcttt tatatatgtg
    33961 tatatagtat ctggccaatg aagcataggt acagagaaaa attctaaagt tttgtcccca
    34021 attgataatg tatctccatc tgtaactgca acatattcaa agtctttgtt tacgatttcc
    34081 ttaagatatt taattgctgt ttctgaagct actacttttg catttttagc taaatccaaa
    34141 agcttttcaa cgcttcctgc atggtctggt tcagtatgac ttacaacaat atagtctatt
    34201 ttttcaaaat ctatatttaa atcatttaat ctttcaatat aattgtcaaa atgcttatct
    34261 ttaactgtct caaacaaaac tgttttttct gttcctttta atacatatga attataagta
    34321 gttccataag gtgtatacat aattatgtca aatactctta aatcagggtc aagtgaacct
    34381 acccaatata aattttcttt tatttttagt gatttcaatg acataccgta ctcctcctaa
    34441 aatagttatt tagtctcttt ataccctgct tgttatattt taaacaaaat ttattcaaaa
    34501 aagaaattat tttaaagata gtttaaatct tctaatcttc tttttctacc ttcaatacag
    34561 ttcccttttt agaatctact tttatgtcat attcattttt atctttatct attcttattt
    34621 tataaaaagt aacatctaaa tctttgtcta aactccattc tttaaccatt ccattttgtt
    34681 cttttaatgc aatttccata gcttgttgag gtgtaattat gtcatttaaa tctaattttt
    34741 cttttctagc aactccattt aaatcttctg aatctaactt ttctgtttta tcttctaata
    34801 catcttttgt attagcatca attttcatct tatattcatt attatcatct acaccttcca
    34861 cagtataaac aaatttattt aaatctctct caagacttaa atctactata tcagcatcct
    34921 tgtatttatc tttaaatatg tttattgcat ctgtgtatgg cactttaaaa tcttgttcca
    34981 ttaaattttc attatttttt tcatctttta aagcattatt tgaagcattt gcctcctttt
    35041 ttgtattatc ttgtgcttgt cctgaatcct tagttgggct cccactacat gcagttaata
    35101 aacctgctat aagtatactt accactaata aatacgtttt tttacacata aaaatcctcc
    35161 ttaaatatat taatttattc tatattatgc cctctaaacc ctttatttac ccttttatat
    35221 taaaaattcc tcctatttta tcaattttaa aactttatat ttactaaaat taaagttaca
    35281 taaaaattat actgtctcaa aatagaaaca agcatctttt tcattgttga aataataaaa
    35341 atatatttta tttcgtacaa aaagagtgcc tcatgaacta aaaagttcat tttgagacac
    35401 tcccattctt ttatattttt acttacaaaa taacagtact tattaatttt ttacaaacct
    35461 tataagtata tctatattat attcttaaat ttaaacacta tattaaaaaa ttaaattttg
    35521 tttaattctt ttactgttaa atccatttta ggatatggaa tcgtaattcc ttcttcgtca
    35581 aacctaactt taacctcttc tagtaaatca agataaattg tccaataatc ttctgtcttg
    35641 caccaaactc tagttgcaaa tttaacagca ttatctccat gttctactac tcctataaat
    35701 ggttctggct catttattat taatttatga ttattaacaa tatctttaag tactcttcta
    35761 acatgtagta tatcatcttc ataccctaca ctaaaagtca aatcaactcg tctagtattc
    35821 tttgctgaat agtttattag actatcattt gatacagaac cattaggtat aagtatctgt
    35881 ttattatctg gagtaaccaa ttgtgtataa aaaagtccta tttgttcaac cgttcctcca
    35941 tggcctgctg cttctacgta atctcctact ttaaaaggtc taatcaatag tataataaat
    36001 cctccagcaa aatttgatag actaccttgt aaagccaaac ctattgctac ccctgctgat
    36061 gctatcacag cagcaaaact ggacaaactc attccccaat attccagaac aatgattata
    36121 acggcaactt taagtacact caaaagaaga gacttcaaaa accttcttaa agttaaatca
    36181 atatctcttt tactaagtac taacataaca tggtttacaa atttttttat tattttaaat
    36241 ccaatagaaa gtataagtat acctattata agttttactc cgcttgtagt agcccattct
    36301 agcagacttt ccattatacc tcccatatcc atcttattaa tgtctaaatt atttaaatct
    36361 aacttgctta tatcatctat tttcgtcgta tccataaaaa actccttacc ttatatttta
    36421 gaaccaatat tatagtttaa agttcttatt ttctatttaa tataatacaa taccatttgt
    36481 acatagtaaa caagatttat attccaatta tacatcttag gaaaatgcaa actatttgtt
    36541 atatatatgc aaaatataat actaaattaa actattaata aaacactata tagccttaca
    36601 atcatcattt tttaccccta tatgagatga tactatagtt ataatactta gtactataaa
    36661 tactacaaaa ccttttttat atccatcaac tatattatat gaatttactt gtaaagagat
    36721 agctataatc aaattaataa ttccacttcc tataaattca aaagtattaa taacactagt
    36781 tgccagtcca gaataaattt ctttattttt atacttggca tcattaaaaa cctgtagatg
    36841 tgacataact atacatccca taataaagaa tgatattggt aaaactataa ttggtggttt
    36901 tacctggtat acaactacaa ttacaatcca tataaacaaa tctatcattg ctccaaattt
    36961 tattatatta aatttgctag accttatttt agcaaataca aaatccataa ttattgaacc
    37021 aaatataaat ccatatgtaa aaaatgatac tataaacgca gaaaaactct tactcacacc
    37081 ataaacgtcc attatgtatc ttactcccca caagcttata aatgcacttg taagaccaac
    37141 aaaagagaac attatcattg aattatacca tgttgatttg ttctttataa cagacttaat
    37201 accatcaaca atattaacct tctctgactt ttcatagggt tcagtatcta cattgaatcc
    37261 atactctttt ggtgtatctc taacaataat atatataaaa catccaatta caacaccaat
    37321 tataccgatt aataaaaatg aatttctcca accaacaagt tcagacaaaa acacaagtgg
    37381 aaaagtagca agaactccac ctaaatttcc tacaaatgaa aatttagctg ttgcagaagc
    37441 aaattctgac ttattaaacc atctcccttg aatttttaaa atacaaagta atattactga
    37501 tgttcctgcc cctacaatta cacgagaaat atatgctaat tctatacttt gaatcaaacc
    37561 aaataaaatt gaccctaaac ttgccattat tattccaaga ctgctaattt ttcttgctcc
    37621 atatttatca atcaaaattc ctgcaggtat ttgcataaat gcatatgcat ataggcaaaa
    37681 ggatgctata tttgaaattt gtatagaatt aaaacctaac tcatttgcta aattgtctga
    37741 aacaacagca gttgacatcc ttaaaaataa tactaaaaca aatgaaaatg taattatacc
    37801 ccaaacactc cacttagcct ttgtataact tttcatatct tctccctcaa atccatatat
    37861 ttttaaattt tcttgatata acttatataa agtgtatagt tattcttaca aatttttaca
    37921 cgcaatatca ttatacaaca tatgtatata tttaactaga aataaaatac tattcatatt
    37981 atatacatga attaactaca taaataataa gagccatctt ttaacattac tcaaaagatg
    38041 gctccatata aaaacattta ttctaaattt aattttttat ctaatataaa ttttgtagcg
    38101 aaaaataacg ctattgcaac tacaagacta ccaagtattg caagcataaa actaggactc
    38161 tgataaagat gatataccat atttgtatct tcatttggta agatgcttcc aactgcatct
    38221 ccaacaattg atattactat atttatagct ataaaagaag caaatgccac tatgtttcta
    38281 tgtttattga attttggtaa ttgtcccatt gagattgatg tatataataa caaaataaat
    38341 gatgaatatg aaataaacat tactactact aataataaaa tatctaaaaa gttttcagaa
    38401 atccatttaa aactagtgtt aaacaaatct aaaatttcag gtagtaaaat tccagaagta
    38461 ccaaaaagca taagaactcc aaaagtgaat actgcaacta taaaactaag tacagcgtat
    38521 ataagtgctg ttatacattt agataatata agtgaactag tgctaacagg aagagtaaac
    38581 attaaataac cttcatcccc caaaagattt tttctaaacc tttgaattgt aactacaata
    38641 gttaaaactc ctaatgccat aaaaagactt gttaatacta gtattcctat tccctgtacc
    38701 tgaagtatat ttgtattcat aaatattcca ttaaatacag ctactatcaa tatggctata
    38761 tataacggta taaatattct tccacttgct tttaactcat attttaataa tttacctaac
    38821 atttaaattc ctccctaaat aatgcatcta tagattttcc tttttcttct cttattgctt
    38881 caacgtctcc ttgtaacact atttctcctt ttgatatgaa tattatctca tcacatatgt
    38941 tttctatttc acttattaag tgggtagcaa tcagtaaagt actatcttca gaataatttt
    39001 ttaatatagt cttaagtata tatgaccttg cagctgggtc aacaccacct ataggttcat
    39061 ccaatatata tatgctcgca tttcttgaca ttactaaaat aagttgaact ttttctttag
    39121 ttcctttaga cattgtcttt agcttttcat ttacatcaat atctaagctt ttaatcatct
    39181 catttgctct tctaacatca aaatcactat aaaaatcata gaaaaactta agtaaatctg
    39241 ataccttcat ccaatcattt aaataagttc tttctggtaa atatgaaact atttttttag
    39301 tatctatgga tggtttcatt ccatttatca taatttcacc attatcaggc tgtaataatc
    39361 cattcattag cttaatcatt gtacttttac cacttccatt aggccctaac agcccgacta
    39421 tttttccctt tggtatattt aaatcaatat tttttaaaac attcttagtt ccataactct
    39481 tgtttacacc tttaaattca actattccat cttgagaaac attgcttata tttttatcca
    39541 ttttataatt ctcctttcag attttctgta ataagtttta gcatttcatc tctatcatat
    39601 ccaagctttt ctaaggttac ttttaatgta tttatctcca cattagctat ttcctctttc
    39661 atagctttta ttttttcctt atcatctgtt acaaatcttc ctttagttct ctgactataa
    39721 actaaacctt gtctttcaag ttctgttaga gccttttgca ttgtatttgg attaacttcc
    39781 gcatcttctg ctagtgctct cactgtttct aatttagatc ctattttaat ttcccctgaa
    39841 attattttta actttaaatg ttctactaat tgtatatata taggtttgtt attatcaagt
    39901 tcccattcca tgttcatgcc tccttattat attattgtat taatttatta atacaataat
    39961 ataataatac aaagtatatg tcaattactt tttagtaaaa gtataaaaaa tttcacaaaa
    40021 aaaatgaaca ctacattaga gtccattttt aacacaattt attaaattct ttatattaca
    40081 gattaattac cctcttacca agttggatac aattaaatgt tcaaattctt caattggcat
    40141 tggctttcca aacaaatatc cttgtgccat atcacacttt acttctttta aaagtttaaa
    40201 ctgttcttct gtctcaactc cttctgatat gactttcata cccaactctt ttgccatttc
    40261 tattacttta gtaacaatta ttttgcttct tttactatta taagtttcca taataaattt
    40321 ttggtcaagt tttaagatat ccataggaat ttcttttaac atatttaatg atgagtaccc
    40381 tgaaccaaaa tcatccatag atattaaaaa tcctattttt tttaaattat tcattatatc
    40441 aattaaaata tcaaaattat caaatatgat actctccgtt aattcaagtt ctatatactt
    40501 tgcaggtata ttgtatttat caattatatt tttgtatgtt tctataaaat tattgcaata
    40561 taaatgtatt cttgaaacat taactgaaac agtaactgga tttattcctg catcaatcca
    40621 ttttctaagg tatatacata cttcttcaag cacatataaa tctaaattta taacaaaacc
    40681 gtttctttca aaaaatggga taaattcatt tggaggtatt agccctttat caggacgttt
    40741 ccacctaaca agtgcttctg aaccttgtat ctctcctgta ttaagatcta tcttaggttg
    40801 taagtatata ataaactctt tattttctaa acttgaaaac attgtatttt ccatctcttt
    40861 ttcttttatc tcttggtcat gaatcttatt atcataaaat gcatatgaac ttttatgtcc
    40921 tccctttgcc attttatgag gtatattagc cctatctatg attgagttga tatctctatc
    40981 ttctggaagt ataaaataga ttccacaact taaaactaac ttatactttt cttcttgatt
    41041 attattaaac aagtctaatt cctcaaatat agtttttaac ctctttgtta tatcttcttc
    41101 ttctatatat ttcataatta taataaaatt atccgcagat attcttgcaa acatttcctc
    41161 ttcaaatata ttactcttaa taatttttgt taaattacgc aaaatttcat tcccaacttc
    41221 atatccaaat aaatcattta tatatttaaa tttatcaata tctatatata ataaagcata
    41281 ctttacttga gtatttttac atagtatttt gttagcatca attacaaatt tatctatagt
    41341 atttgctcct gtaagattat ctgtatatgc tatcttttgc aatttaattt taaaatttaa
    41401 tttgtcatat attatataga atataagcat catacatatt atagccataa taagtattat
    41461 ttgtattgca tatttgctaa taaactgatt attagacaca atagactcaa agttatttat
    41521 ggagttgttt ttatagagtt tgcataaaga atagactggt gttgtgtatg taatttgtaa
    41581 aattatacaa ataaataaaa aaaacatcaa ttttttttgt aaattcctca taaaaatttc
    41641 ctcccattaa aacacctcta ttttattagc aaataagtac atctcaaaag tttccatttc
    41701 ttgtaaaatg gatagttttg aaaagaaaat attaaaatta
//
LOCUS       DAMJWO010000033        39310 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.034, whole genome shotgun sequence.
ACCESSION   DAMJWO010000033 DAMJWO010000000
VERSION     DAMJWO010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 39310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39310
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.034"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(76..927)
                     /locus_tag="PC366_001731"
     CDS             complement(76..927)
                     /locus_tag="PC366_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2577261.1"
                     /translation="MNSKIKYFLKFFILIFILIFIYSVAIEPSLLIVKKYNISENGAL
                     IKNDTIESKSESVKVVQISDTQIGSFYSTKNLKKVANKINTLNPDIIVFTGDLIDYSN
                     KNPSVDEITTILSSMNARLGKFSVFGNHDYMYKLPRYYRQIMKNSNFNLLVNENKKIK
                     LKDDKYINILGVDEILNGNPNIKYLESQIDNKNFNLLLAHEPDLVDMLSKDTMNLVLS
                     GHSHGGQIRLPIKGALVTPPYGRKYTKGFYDINGNHLYVSSGLGSTKLPFRFFNIPEI
                     IEFNIII"
     gene            complement(953..1891)
                     /locus_tag="PC366_001732"
     CDS             complement(953..1891)
                     /locus_tag="PC366_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF2577262.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYNGFK
                     EHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDNLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFIINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEIIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            complement(1994..2644)
                     /locus_tag="PC366_001733"
     CDS             complement(1994..2644)
                     /locus_tag="PC366_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF2577263.1"
                     /translation="MKKNYEIVLFDLDGTLTDPKEGITKSIQYSLNSFGIKEDLENLD
                     QFIGPPLHDTFKEYYKFEDKKAKEAVEKYREYFADKGIFENKIYENMKEILEMLYKNG
                     KILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEELSESEPTYIVENVESIKDILL"
     gene            complement(2794..2982)
                     /locus_tag="PC366_001734"
     CDS             complement(2794..2982)
                     /locus_tag="PC366_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HDF2577264.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            complement(3089..4273)
                     /locus_tag="PC366_001735"
     CDS             complement(3089..4273)
                     /locus_tag="PC366_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2577265.1"
                     /translation="MKNLLIRNGTIISPTDGIKFEKRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPSNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTSLDVINFDKVESIVEKNI
                     EKIKGIKVKASKFQSNESGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKESGTLRKSVINAKNRGVLFDVCHGVDQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLNVINKIMELGISLEKCIEKVTEYPTKIFDLHGNKGRI
                     KIGGEGDFTIFTMEECNDIIKDYNNNELVLNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            complement(4415..5332)
                     /locus_tag="PC366_001736"
     CDS             complement(4415..5332)
                     /locus_tag="PC366_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HDF2577266.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTEAGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGEGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVILEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
     gene            complement(5354..6082)
                     /locus_tag="PC366_001737"
     CDS             complement(5354..6082)
                     /locus_tag="PC366_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2577267.1"
                     /translation="MLEIKNLSFNVESNNEELGIINDVSLSFERGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESNQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            complement(6278..6478)
                     /locus_tag="PC366_001738"
     CDS             complement(6278..6478)
                     /locus_tag="PC366_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577268.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            complement(6603..6983)
                     /locus_tag="PC366_001739"
     CDS             complement(6603..6983)
                     /locus_tag="PC366_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2577269.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMKQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRMFSFKDQDGNDYLVREDK"
     gene            complement(7256..8614)
                     /locus_tag="PC366_001740"
     CDS             complement(7256..8614)
                     /locus_tag="PC366_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2577270.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTIMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDSEKVNETIKQALVSGVILSFTITILM
                     WVFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIATQQIANGILRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGIDLNPLGINLQTPSYGITGAAISIAIARIIGCIVIIRAL
                     FKGNEFISMGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFIV
                     GAIFIPIAPWISSMYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     VA"
     gene            9062..9514
                     /locus_tag="PC366_001741"
     CDS             9062..9514
                     /locus_tag="PC366_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staygreen family protein"
                     /protein_id="HDF2577271.1"
                     /translation="MVNLNANNLNVNMVYPISSTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTLGLGTMNIDKVYGQWAWFTDNIYDLNLFVFVGNYPYQIAKNRYDTFVDILPVA
                     ITSIVNGDRVFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            complement(9671..10288)
                     /locus_tag="PC366_001742"
     CDS             complement(9671..10288)
                     /locus_tag="PC366_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HDF2577272.1"
                     /translation="MEIFAIGHSNYPYDKLINMIKKYDINCVVDIRETPYSKYNIQYN
                     KEAFNESLRNSGFIYIYMGKEFGAKRNNKDVYTQEGYADFEKVAKEDIFLNGIERLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKVLNKEGFDVKYIMHEGNLAYQEDIEESLLD
                     KYFSDREQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
     gene            10837..13497
                     /locus_tag="PC366_001743"
     CDS             10837..13497
                     /locus_tag="PC366_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HDF2577273.1"
                     /translation="MKKILKRLCTGFLAFATVVTALPSSTVHASNTQYWTESKERVSI
                     VEQVMNDGSISSTFNEGHLTVEGEDAYCIDINTAFKNGYKTKADASTRMSADQIADVA
                     LSIEYVKQYTDIHSGISSKHAYLLRQLVVWQRLSVQPDWQWDNVRASYDEIPKAVQDE
                     VFAGAKAFVKENKGRYDCGGYIYSGEGQELGQFWAKLAVGNTKLQKTSTNANITDGNG
                     IYSIAGATYGVYSDKDCTKQLTTLTTDTSGNTEAVEVRATIVYIKELSAPAGFKIDKT
                     VYSLSVEVGKTATLKVSDTPKVTDTLIELFKIDMETQKSNPQGNASLEGAEFTWNFYA
                     GYYNKNNLPAQPTRTWVTKTIAEKDSDGAIHYITRLADKYKVSWDSFYTQDGKNVLPL
                     GTLTVEETKSPSGYLLEGTYMQADGSEEQIKGMYLTQITEDGDLAVLSGSNQYHVSDK
                     VIRGGVKIQKRDLETKDTKAQGGATLKDTAFEIISLNENAVLVEGKLYKKNEVLKTIH
                     TDIEGIASTSADLLPYGKYRLSEQKPPEGYLTDGAKPIDFEITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGSHKRLADVPFRITSKTTGESHVVVTDDNGQFSTASDWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALLYDTYIIEELRCESNKGFKLIPPFEIVISRN
                     KVVVDLGTLTDEYEKEITIHTTATSKDGEKTILAGKDVTITDTVKLDGLTKGTKYQLK
                     GWQMLKEENAELIINDKRIENDYIFTADSETMEVKIEFTFDASNLGGKQLVTFEELYD
                     LSNPDEPIKVAEHKDIEDDGQTVTIKEVPETPTPEEPEKPTTPDTPTKTDSPKTGDNT
                     NILAFAIMMFVSAGGLAGTYFFKHRKMKKS"
     gene            13722..14045
                     /locus_tag="PC366_001744"
     CDS             13722..14045
                     /locus_tag="PC366_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDF2577274.1"
                     /translation="MELKYIVPNVAQTFGNLEFAGENKVDQQRINGRYTLVSRSYNLY
                     SDIQRADDIIVVLPAKAGEKHFKPEQKVKLINPRITAEGYNVKGRGFTNYILMADDML
                     PAESK"
     gene            14060..14443
                     /locus_tag="PC366_001745"
     CDS             14060..14443
                     /locus_tag="PC366_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDF2577275.1"
                     /translation="MRLTNGIVLDNEKTFGVLKFSALRHEVRVENEDGTTSDEIKRRT
                     YDLKCSVQERMIQVSIPADVPVKDFPYNAEVELINPVADTVANANFRGTTVDWYIKAD
                     DIVLKNKGGQAGNPQNNAPQGQQKK"
     gene            14539..14952
                     /locus_tag="PC366_001746"
     CDS             14539..14952
                     /locus_tag="PC366_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HDF2577276.1"
                     /translation="MLDKIPNAEEMTALVGQSLYSVWNELCALIDEKYEMECLWNKGG
                     KAWNYEYKYRRGGKTLCALYARENCVGFMIILGKDERLKFDTYRDNYSKEVQRIYDET
                     KTYHDGKWLMFEPTDTTLFDDFVKLLRIKRKPNRK"
     gene            15059..15517
                     /locus_tag="PC366_001747"
     CDS             15059..15517
                     /locus_tag="PC366_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2577277.1"
                     /translation="MKLKNPMLVVTDIDKSVEFYKKVFGLYVIMDFGANKTLTGGLAL
                     QTSETYKEFIGTSDISFGGNNFEVYFEEEDFDKFADRLKEYDIEYVHPIIEHSWGQRV
                     VRFYDPDKHIIEVGENMKIVCKRFLNSGMTPEQVAERMDVPMKFINACMR"
     gene            15542..16084
                     /locus_tag="PC366_001748"
     CDS             15542..16084
                     /locus_tag="PC366_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF2577278.1"
                     /translation="MKGFERKNQLFSLCGLNCGLCPMLLGNYCGGCGNGNQSCRIAKC
                     SLEHGQIEYCYECKQYPCEKYQHIDDYDSFITHKRRKADLERAKNIGIEQYNLEQQEK
                     TQILSYLLSNYNDGRRKTFFCVAVNLLELSELQEAMKQIQSNDELTLLPFKAQCLYVV
                     EVFQKIAERRNIKLKLFKKK"
     gene            16120..16647
                     /locus_tag="PC366_001749"
     CDS             16120..16647
                     /locus_tag="PC366_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcxB family protein"
                     /protein_id="HDF2577279.1"
                     /translation="MTNGGIPLETVELRFQYTQSEYIKAERQYLISSKTIHKYDIALV
                     AVFLLLSVVYMLFSSFSVFSILIFGLIIVVTALGSYLYILMPILKFKQTAKYHEEYTL
                     VFSKENIKFKTQSIDSEVKWDIYSALWESHDFYYLIQAPRLYTLIPKRIFKDLNEKQL
                     FEEIAQSRVKTTKHI"
     gene            16757..18151
                     /locus_tag="PC366_001750"
     CDS             16757..18151
                     /locus_tag="PC366_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2577280.1"
                     /translation="MRMILNKGHRIRARDKNLVYHFSIGTLLFVFVAVLLLLNIKQLM
                     RTDWEHFSLLDNGLTLSPYNFITILIATGICALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIVWFPKIYYQMENGLLHIHCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRISIDEVKAENGCLRLMKNLV
                     WEYDVLPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEDMIDCVNAFYEGMVQRSEEMKQHPDYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGSLAFVRQ
                     DGTATCEAKGDGTD"
     gene            18431..19552
                     /locus_tag="PC366_001751"
     CDS             18431..19552
                     /locus_tag="PC366_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDF2577281.1"
                     /translation="MAGISREHLSRIEAGKVALTEDMKHKLLEAVEKFNPDAPMFLLF
                     DYVRIRFPTLDIQHVIKDILKLNIDYMLHEDFGHYKYTEHYYIGDVFVYTSQDKEKGV
                     LLELKGKGCRQFESYLLAQERSWYDFLMDALVDGGVMKRIDLAINDRTGLLDIPELIE
                     KCKNEECISKFRSFKNYGSGELVKHNEANKDGMGHTLYIGSFTSEVYFCVYEKNYEQS
                     SKLGIPIEEVPIKNRFEIRLKNEHAYYAIRELLTHYDAELTAFSIINQYIRFADKEAN
                     KRKSDWKTNARWSWFIGEGRPPVKLTTKPEPYTLQRTLNWLQRQVAPTLKMLKQIDAG
                     NQMDYLKTIEQQAKLTDKHKQIIRQQTASVDELIEKEKE"
     gene            19559..19693
                     /locus_tag="PC366_001752"
     CDS             19559..19693
                     /locus_tag="PC366_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HDF2577282.1"
                     /translation="MWELIKDLLLVSLGMGIGVVLMCIMSVGKEADRHMIELKESEEK
                     "
     gene            19694..19915
                     /locus_tag="PC366_001753"
     CDS             19694..19915
                     /locus_tag="PC366_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577283.1"
                     /translation="MNFGQNLYTWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALVAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            20235..20873
                     /locus_tag="PC366_001754"
     CDS             20235..20873
                     /locus_tag="PC366_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol acetyltransferase CAT"
                     /protein_id="HDF2577284.1"
                     /translation="MEYKYTKIDLNKWNRGKLFQSYIDNMRIVMSLTVDIDVTKFIEF
                     SKKHDLKFYPAMIWAVSKVVNEHDEFKYSWDNNGNLIKWDYISPSYTEFHKEDENFTK
                     IVTDFSDSIFEFHKRFILDREKYKTERAFVENQSLNFFDVSCLPWVKYNHFDVHVFDE
                     GKFLAPVITWGKYELEQERYIMPLTMNIHHAVADGFHLSRFFNEVQELINSI"
     gene            20950..21138
                     /locus_tag="PC366_001755"
     CDS             20950..21138
                     /locus_tag="PC366_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577285.1"
                     /translation="MKDIFSDMQASIGCTYISDLPHHKRMVWQEMKRLNLADYPQKQL
                     EDFAGYVFGVPYTSIAEA"
     gene            21159..21656
                     /locus_tag="PC366_001756"
     CDS             21159..21656
                     /locus_tag="PC366_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDF2577286.1"
                     /translation="MNEMRVCIESRLHTSEEIRSAWFTLPIDEEELEEQIGVPIDSED
                     YHIVEKELPFADEVGEDATIEKLNDLYHTFESLPADLQEDYGELMCYFTSLDELHQHR
                     HDVIHYSWCKNMADVARHLLDNDPAFSAIEERLTRYFDYEAYGQYLDDNGEFIETDHG
                     IYELP"
     gene            21672..22175
                     /locus_tag="PC366_001757"
     CDS             21672..22175
                     /locus_tag="PC366_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDF2577287.1"
                     /translation="MVEDMRVYIANLGKYNEGYLVGDWFSFPIDEEDVAERIGLNERY
                     EEYAVHDTENFPIEIGEYISIEELNEMYEMICELPDYITDSLDEFVSNYGSLEELYDH
                     RDDMILYAGCEDMTDVAYYFIDELQALGDIPPSLQNYIDYEAYGRDLSFEGTFIETRY
                     GMCEIPW"
     gene            22288..22677
                     /locus_tag="PC366_001758"
     CDS             22288..22677
                     /locus_tag="PC366_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2577288.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDLPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITFALRPKITY
                     AGKAVKLDKQVLHEAITAVRSVSYVPD"
     gene            22664..25096
                     /locus_tag="PC366_001759"
     CDS             22664..25096
                     /locus_tag="PC366_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2577289.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSSRSIQEQSKKLVTGRLKDVAYQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTDQSMNLKSVKQSAFLTFKEFIHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLDKNDFGYLIEHIYGRDGVAYEDYEYSLPKKKLKKE
                     TLITHYDLIRPTRCLVEESQRHLRLEHEDSESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALSTVRNKKKELKDLDNHAYQSGSETSSNVVDALDSVD
                     ELETDLDQSRESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYIGYSVDTGRNVYLQPS
                     LASQGVKDTVTNALASAFVESLGGGKSFCNNLLVYYSVLFGGQAVILDPKSERGNWKE
                     TLPEIAHEINIVNLTSDRENAGLLDPFVIMQNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRAVTQSDQRGLLHVIEELRKEDTPISCNIADHIDSFTDYDFAHLLFSDGTV
                     QNAISLDNQLNIIQVADLVLPDKDTTFELLSVSMLIVISTFALDFIHSDRSVFKIVDL
                     DEAWAFLNVAQGETLSNKLVRAGRAMNAGVYFVTQSSGDVSKESLKNNIGLKFAFRST
                     DINEIKQTLEFFSIDKEDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFEELLHAF
                     DTRPPIQRNEVE"
     gene            25096..27231
                     /locus_tag="PC366_001760"
     CDS             25096..27231
                     /locus_tag="PC366_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDF2577290.1"
                     /translation="MKERIKSVFTRKKIFRFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINTENLYSKYPLSNYQLDFYADNNWAWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     RLYLSNATGYVVQEAYKLDFINDMADSIGRSIQTLAGVTQNGFSTSGFYVGFLLLIIL
                     VVGIYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKVNDFSSDISTAS
                     LDLGTKIMLPDSDSKGKDSVDLIRDSLFSIQVQQPWLLLQFGNSGIEEIGADRVEALV
                     SASPEDEDGKTREEVVKTEIEDNDNNNLTILQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVYFAGIYMKLGDLMSMFSLNAGDSQSMGRRIFRRP
                     YLFMRHRARRMEHRLARAVSAGGVAGAVAGGVVASSKSTRQNGTKNNRGNTSSSMGQK
                     AGSAVGAVLDTKNKVKDKATAVKENIKDMPTQTAYAVHSAKEKAKSSVSDFKRGVVQE
                     KENRQSGRLKKQQLHRQNIADKRMELQKAQESRQAGKKTDGSATSGATRPHERPATTS
                     KVNVEKQQEVKRPAIASTVKNDEPIKKNVVKERPLSSGDTSAKTVNQETTRQNYKTDR
                     VTKTTVQKHTQQNTEKNKRTVFKKGQKKK"
     gene            27228..28235
                     /locus_tag="PC366_001761"
     CDS             27228..28235
                     /locus_tag="PC366_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HDF2577291.1"
                     /translation="MKLRHIAIVGSLFSILFSLVLFFGVLISAEDDDGGNGYSSNYVG
                     MNLSAEVLKHQPMVEKYAKENGISEYVNVLLVIIQVESGGTAEDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCKNQGISDINVVIQSYNYGGGYVGYVAGNGKKHMFNLA
                     ENFARDKSGGQKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLVVNQVSGELAQKVM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLVQWCYNKAGVSLPRTAQNQYDATQHIPLSQA
                     KAGDLVFFHSTYNAGSYVTHVGIYVGNTQMYHAGDPIGYADLNNAYWQQYLICAGRIK
                     Q"
     gene            28251..29144
                     /locus_tag="PC366_001762"
     CDS             28251..29144
                     /locus_tag="PC366_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDF2577292.1"
                     /translation="MFKKKEKPVKETKVRTMKVGTHKKSVIALWVVLIASVSFGVYKN
                     FTAIDMHTVHETETIQLRLNDTNGVENFVKNFCKSYYTWDNSKEAIEARTQAISNYLT
                     KELQDLNLDTIRTDIPTSSTVTNVLIWDIKQSGTNDFIATYEVDQQIKEGEQTSNVKA
                     TYTVKVHVDKDGDMVIVQNPTIAPAIEKSDYEPKAQEADASVDADTVNDATAFLETFF
                     KLYPTATEKELAYYVAGNVLEPIGRDYLYSELVNPMFTDDRDNVKVRVAVKFIDNQTK
                     AMQVSQFELVLHKDSNWKIIM"
     gene            29357..30214
                     /locus_tag="PC366_001763"
     CDS             29357..30214
                     /locus_tag="PC366_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2577293.1"
                     /translation="MYKEVGISSNNVPITLSIWYTERNSPTIVFLPGTMSHPLMYENF
                     LCGLSERGFNIIGIHYLSHGKSPKIKKNYTMEDLLHNVYDATTYGIENFGENIAVMGS
                     SQGGILAAMAAGRDTRLKAVFPHNIMLTTLKETMSLTKYPAWSHRFMGLIQLGFRVGG
                     KLLPNYKVPGDAYLDYDRVFYSEQAKQDCLNDPMLLPYYPLRFVASLFNADLSCLENG
                     AIQCPVILITAKGDPLFRFDYTNKVFDLIHVPKKELLTLELNRHMIFNEDTDTTINAL
                     EATLHKYLG"
     gene            30292..30873
                     /locus_tag="PC366_001764"
     CDS             30292..30873
                     /locus_tag="PC366_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2577294.1"
                     /translation="MPRFTEQEKEIINSKLLIEGEKLFSLYGLKKVTVDDLAAAVNIS
                     KGSFYAFYPSKEHLYVEINFRLQKELFTSIETTVKKKKYKNHRDLAKDVIMLSLTGVI
                     TSPILSQIDLSLMDYLQRKISSDIFENHMYSDIRILEILEGLGVVFLVPHTVIIKSLY
                     SVLSCLEQFKEDEELNMVQNLLVNGIIQQVVAE"
     gene            30977..31822
                     /locus_tag="PC366_001765"
     CDS             30977..31822
                     /locus_tag="PC366_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577295.1"
                     /translation="MIDVKKLYFSYTDKPFVENVSFHVGRGEIFGFLGPSGAGKSTIQ
                     KILTGLNTSYKGSVKVAGTEIREHTNRFYENIGVDFEFSTCYEKFTARQNLAYFASLY
                     DKQPRSIDELLHMVGLENDGDKKVADFSKGMRSRLNFIKALVHDPDILFLDEPTSGLD
                     PTNNRLMKDIILAEKKRGKTIIITTHNMYDATELCDQVAFIVAGKVSALDSPHNLIMS
                     RGAAKIHYTYYDKGEKTGECLLDRTTEDKLLKSLISENRLLSIHSSEPTLNDIFVDIT
                     GRTLQ"
     gene            31819..32502
                     /locus_tag="PC366_001766"
     CDS             31819..32502
                     /locus_tag="PC366_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577296.1"
                     /translation="MRLGRLICGDIHFQWKYGFYFIYFILTVLYVCGIAALTGHWKTD
                     IASIMIYSDPAAMGLFFMGAIVLLEKSQKVLNAMVVSPVKVSEYILSKTIALIAISTI
                     IAVILGFVSGSNHLLGIAVGTALTSAIFTMLGIIAATKISNLNQFLIVIMPIEIVCFV
                     PPIVGLFVKLPDIFRFFPFTACMNLITGKSILLSFDMVLVIATLIILYIVARHTVKHM
                     WRSLGGVKL"
     gene            32499..33197
                     /locus_tag="PC366_001767"
     CDS             32499..33197
                     /locus_tag="PC366_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577297.1"
                     /translation="MKRILSSTIQVFKQIKSDPMMFAACFTPFVMGALIKFGIPFLDG
                     ITDFSLQTYYPIFDLLLSIMAPVLLCFAFAMITLEEIDDKVSRYFSITPLGKSGYLFT
                     RLGVPSIISAVIAFIVLLLFSLEKLSIGMTICLALLGSVQAIIVSLMIITLSSNKLEG
                     MAVTKLAALTLLGIPAPFFIDSYYQFAVGFLPSFWVAKAMQNEAVLYFSIGLMVALVW
                     YYFLIKRLFRKLAG"
     gene            33209..34120
                     /locus_tag="PC366_001768"
     CDS             33209..34120
                     /locus_tag="PC366_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF2577298.1"
                     /translation="MEKGRLLQNENINKAIQVSKITLIINLGLSLLKFAAGYIGKSSA
                     MLSDAVHSASDVLSTIVVMVGIKISEKQPDKEHPYGHERMECVASIILSVALAITGAG
                     IGYSGIKKIFSGQYNTLSVSSGIALTAAVLSIVIKEWMYWYTRSAAKHTNSDALMADA
                     WHHRSDALSSVGSLIGILGARLGYAILDPIASIVICGCILKAALDIFKESINKMVDHS
                     CDNATETKIREVVLQQQGVDGIDELKTRMFGAKMYVDIEILADGNLALYDAHRIAEGV
                     HQTIENNFPQCKHCMVHVNTNELPYSP"
     gene            34173..34313
                     /locus_tag="PC366_001769"
     CDS             34173..34313
                     /locus_tag="PC366_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577299.1"
                     /translation="MEQYWWIIIVMVLIVVGLLKIVIMKKYNQRRNSNNRSKNSEDDK
                     MY"
     gene            34428..34619
                     /locus_tag="PC366_001770"
     CDS             34428..34619
                     /locus_tag="PC366_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HDF2577300.1"
                     /translation="MKKYEYVEINYNAKGVVFLCTDKHKEIIDSYAKTGYHYAGFVPT
                     EIDAKGCMRKIDLIFEKED"
     gene            34643..34873
                     /locus_tag="PC366_001771"
     CDS             34643..34873
                     /locus_tag="PC366_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577301.1"
                     /translation="MIGLKRRDMNYIMKVGAKAQGVSVSEFRAMLQDTIDKTMESTDP
                     DVQANFKRYFGNKRPTPEEYIYTITKKTKVKV"
     gene            35139..35429
                     /locus_tag="PC366_001772"
     CDS             35139..35429
                     /locus_tag="PC366_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577302.1"
                     /translation="MKPSDFQKTIQCQFECKLKKVVKGIIWNYRKELRRRKNKEISFS
                     ELPDITVESLATWDDYETNYTIFNVCGIDIKVLDDELAEALKQLPEKNVTMY"
     gene            35429..35563
                     /locus_tag="PC366_001773"
     CDS             35429..35563
                     /locus_tag="PC366_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2577303.1"
                     /translation="MYYFLEMSDTEIADIMNYTREAVFKHRHRALETMKEILNEKTRQ
                     "
     gene            35544..36725
                     /locus_tag="PC366_001774"
     CDS             35544..36725
                     /locus_tag="PC366_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDF2577304.1"
                     /translation="MKRQDSKGRNLRLGESQRKDGRYVYKYTDIFGKPQFVYSWKLVP
                     TDKTPAGKRDDISLREKEKQIKKDLDDGIDTVGGKMTVCQLYEKKNNQRKNIKRNTEL
                     GRQYLVNALENDPLGMRAIDTVKQSDAKEWAIRMNGKGYSYKTIDNYKRSLKASFYMA
                     IQDDCIRKNPFNSKLSDVLEDDTEAKVILTPEQEEKLLAFMETDNVYSKYRDEVILLL
                     ETGLRISELCGLTTHIDMLNRVINIDHQLLRDTEVGYYISKAKTKNGKRELPLTERAY
                     QALKRILKNRGKAQPLVVGGYSNFLFLNREGLPKVAGNYESMVRGLIKKYNKTHKDKL
                     PNITPHSFRHTYCTNMANKGMNPNTLQYIMGHANITMTLGYYAHGTFQSAKAELERLA
                     S"
     gene            complement(37065..37877)
                     /locus_tag="PC366_001775"
     CDS             complement(37065..37877)
                     /locus_tag="PC366_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2577305.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKKAVENPEEVENILMNKEKEMLDVIKSEEYKIIKLRN
                     YLMNLKGEVNMNDVIIKSLPKVKVASMRKVLKGYDELFNLFPNVMAEEMMKTGCTCAV
                     PDYCFNIYHDGEYRETDMDVEMCQAINDLKEDTDILKFKELDAVENAVCILHNGPYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRIL"
     gene            complement(37953..39188)
                     /locus_tag="PC366_001776"
     CDS             complement(37953..39188)
                     /locus_tag="PC366_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HDF2577306.1"
                     /translation="MGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITSGVTGMF
                     CHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLRGSLASLLEVESGSNDPIAY
                     MLTLILLTLMNNSGVELIAPMVIKQIAFGLAIGFILAKLSVYILRHSNFEIEGFYTIF
                     ITAIAILSYAFSEYLGGNGYLSVYISGIIIGNSRIPLKKSLVHFFDGISWIMQIMLFF
                     MLGLLSFPSKLPNVFGIAMAISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVGLRG
                     AASVVFAIYAVTQGVAIENDIFHIIFFIALLSVGIQGSLIPTVARKLDLVDDNTPVLK
                     TFNDYDGEISSKLIEVNVDEGNKWANKSIIDSNIPDDILIVMIKRKEQVLIPKGSTII
                     KTGDILVLSGDRIEELIQL"
BASE COUNT        12764 a         7016 c         7048 g        12482 t
ORIGIN      
        1 tggtttaatc catttttaca gtatatacat ctacatatta taaaaagcaa aattatattt
       61 tctaaatatt ttatgttaga ttataatatt aaattctatt atctctggta tattaaaaaa
      121 tctaaatggt aactttgtac ttccaagacc cgaactcaca tataaatgat ttccatttat
      181 atcataaaac cctttagtat atttcctccc atatggagga gtaactaatg ctcccttaat
      241 aggtaatctt atttgaccac catgactatg cccagataga actaaattca ttgtatcttt
      301 actaagcata tctactaaat ctggttcatg tgctaacaat aaattaaaat ttttattatc
      361 tatctgactc tccagatatt ttatattagg atttccattt aatatttcat caacacctaa
      421 tatattaata tatttatcat cttttaattt tattttttta ttttcattta ctaaaagatt
      481 gaagttggaa tttttcataa tctgcctata atacctagga agtttataca tataatcatg
      541 attgccaaat actgaaaatt ttcccaacct agcattcata cttgataaaa tagttgtaat
      601 ttcatctaca cttggatttt tattggagta atcaattaaa tcaccagtaa atactattat
      661 atctggattc aaagtgttaa tcttattagc tacttttttg agattcttag ttgaataaaa
      721 actacctatt tgagtatctg aaatttgaac tacttttaca ctttcagatt tactctcaat
      781 tgtatcattt tttatcaatg ctccattttc acttatatta tattttttca caattaatag
      841 actcggctct atcgcaactg agtatataaa aatcaaaata aatattaaga taaaaaattt
      901 taaaaaatac ttaatttttg agttcaaaat atctacctac ttatttattt ttttaaacta
      961 tttgcattac agactcaact ttgttcattt ttctgtcatg catttttggc ttatttgctg
     1021 aaaaccattt atatgttgct gtaagacctt cttttagtaa cacatttggt atataaagcc
     1081 catgttcaat aagcttattt atatcaagat taaagtctat atttctaaat gggaaatacg
     1141 ttctttctct aaactctact ttttccatat ctacatattt tattataggt tctttgccaa
     1201 taatttctcc acatgtatat ataaggtcat cccaagaaat taactgtgga tttgtcacat
     1261 tataggcctc tcttacatga ggatttttca ttatgctttc caataccttt accaaatccc
     1321 caatatatat aaattgatta ctaacttgtt ttccttttgg tactggtatc ttttcatttt
     1381 tttctatttt ttcaaagaaa taatactctc tatataaatt attattttca ccatatatgt
     1441 aagttggtct aataattata tatggtatag ggctatttat aataaaatct tcagcctctt
     1501 ttttatttaa cccatatttt ccccagtttt cattttcacc tttctcattt tcttctttta
     1561 tatttcttcc actatcttta tatactgctc ctgctgacaa tactatatac ttttttaagt
     1621 tatccatgct tataaaatca atcagattac ttacatcttc ttttgtatat gctgtcatat
     1681 catatatgta atcatatttt cttcctgtga taatgttttc catatctttt cgaacttttc
     1741 tatcacaaat tagatgttct ttaaaaccat tataatctat ttccttttta ccatttgtaa
     1801 gtatatcaat ttgataccca catttaatca agcgcttagc aagtgcagaa cctatgaagt
     1861 cgcttccacc cataattaaa atagatttca ttttaagtgc atcctcctct tttttaaatg
     1921 acttccttaa ctataatatc atatttttaa atatgcgaca ccattttgta atatttttgt
     1981 ctataaaaga tatttataac aaaatatctt ttatagactc tacattttcg acaatataag
     2041 taggttcact ttcactaagc tcttcaaaag aaccataccc atacaatact ccaatagaat
     2101 ctatacctat ttttttagct ccaattatgt catactttct atctccaacc ataataactt
     2161 tatctttatc ttttacatta cataggtcta gtacatattg tataacttca tttttattca
     2221 ctcttgtacc atcaagattg ctacctgcta tatatttaaa atatctatct atatcaaaat
     2281 atctaagtat agtttctgca aaaactgttg gcttagaagt tgctactaat aatattttac
     2341 catttttata gagcatttct aatatctctt tcatattctc ataaatttta ttttcaaata
     2401 tccctttatc agcaaaatat tctctatact tttcaacagc ttctttagct tttttatctt
     2461 caaatttata atactccttg aaagtatcat gtaatggtgg tcctataaat tggtctaagt
     2521 tttccaaatc ttcttttatg ccaaagctat ttaaagaata ctgaatagac tttgttattc
     2581 cttctttagg gtctgtaagt gttccatcta aatcgaataa tactatttca taattttttt
     2641 tcatatttca gtcctccata tttgtaaaaa gtaatatctt acatattaag tttatctatt
     2701 ttaaaaagct atagtaatag aaatttctaa tactatagct taagtaccca attaaatctt
     2761 atatatttat tttaaaaata aatttaaaca gctctattta actgttatag ctgaaactgg
     2821 acatccttct tcggcttctt tacataaatc ttgtaaatct gctggtattt ctccttcaat
     2881 tgctactgaa tgcccttcat cgctcatact aaaaacgtct ggacatgttc ctatacatgc
     2941 tccacaagct acacatacat ccttatcaac aaatgctttc atactaaaat acctccccta
     3001 aaattattat tttttaattg ttgtttcctt agatatttat ccaatatata ccaatttaaa
     3061 catatattta ttattttatc actattgttt agtttattat agtattttcg tatccatgtc
     3121 tataaacttc actgcttttc atccatgatt ttacagtata ttgcaatctt aattttttat
     3181 ttaaaacaag ttcattatta ttgtagtctt ttataatatc attacactcc tccattgtga
     3241 atattgtaaa atcaccttct cctccaatct ttattctgcc tttatttcca tgtaaatcga
     3301 aaatctttgt tgggtattca gttacttttt ctatacactt ttctagggat atcccaagtt
     3361 ccataatttt atttataaca tttaaaagag aatagtttac gtctttcatg ttttttatat
     3421 gcatatcagt acttattagg tcaggctcta aaccttgctt tattgctttt ttaaaaactt
     3481 taaaatcaaa ttggtccact ccatgacata catcgaacaa tactcctcta ttctttgcat
     3541 ttattactga ttttcttaat gtgccagatt ctttaaggat tccatttgta ctatttccat
     3601 atactggtgt aaccacatct ccttttccca aaatattcat tacttcatct atatatgatg
     3661 gatactctcc tatatatacc actaagggta aatttaattt tttagcaact tgctttgatt
     3721 tcttaattat atctatacca ctttcattag attgaaattt actcgctttt acttttatac
     3781 cctttatctt ttctatattt ttttctacaa ttgactcaac cttgtcaaaa tttataacat
     3841 ctaaagaagt tgattcattc aatatattta gtccctcatt tgtaacattt aaaaaagaat
     3901 atacttctgt tttacactca tccatatact tttttttaaa atcatagtag tttgagggac
     3961 cagctgtacc tgcatcaaat ataactgtag aacctttttc aattccaatt gaatcagaat
     4021 ccatacctgt aggtaatttt ctcttataac aatgggtgtg aacatctata aatcctgggg
     4081 aaatatacat attatcggca tttattatct cgaactcttt atttgtaagt aatttttctt
     4141 ttcttatttt ctctttaagg ttcaatccaa tagcatatat tttcccatgt aaaaccaaga
     4201 tatctctttt ttcaaatttg ataccatctg ttggagatat tattgtccca tttcttataa
     4261 gtaaattttt catttattcc acatcctaat tacaatataa tttctctaat agcttttctt
     4321 acataaagaa aataagccta aaaataaaaa tattttagac ttattcacta tattatacta
     4381 tattaattat attaaattaa ataaaatctt taatttactt taagaagcaa ttaagtattt
     4441 gttgctcggc ttcttcttca gtaagaccta atgtcatcat ctttagtatt tggtctcctg
     4501 caatctttcc aatagctgct tcatgtacta aaagagcatc tggatgattt gcagcaattt
     4561 caggtatagc actaatttga gaatttccca taattattga atcacattga acatgtgcag
     4621 aacaaaggga atccccaata acacaaggat taaacttttg cttagaatta tcttgcccaa
     4681 ctgtacgaga aactacttga gcagaagagt tttcaccctc taagataacc ttcatattag
     4741 attctgcaac ttgattacca tgagttaata atttctcaaa tacaactatt ttagctcctt
     4801 tacctaggtt tgcatccatt tctcttttag ttgaatctac acccttaatt tgaattgttt
     4861 ccatttcaca atatgaatcc tcatccatat tgacaatagt aactggattt aaaattctct
     4921 ttccttctcc atcaccttca ccataatgtt tttctacata ttttaggcga gctcctttac
     4981 gtaagaaaaa tctatgtata ccattatgtt cactatcatc acaaccacag ttatgtatac
     5041 cacacccagc aattataaca acatctgcat tttctccaat ttcaaaatca ttatatacca
     5101 tatcctgtac accagcctct gttactatta ctggtatatg tacattttct ccttttgtat
     5161 ttggctttac tataatatct attccaggtt tatcagtttt aggaattata gttacatttt
     5221 cagttgaatg tctctctact ccttgcccat ttttacgtat attgtatgct cctaatggag
     5281 ttccacgaag ttcagcaact ttttctaaaa gatttaaatc tattttgttc atttaatttg
     5341 ccttcctttc taattaattc atgtctttca ttaattcaca acttgaatta acttgacaca
     5401 tgatttcagg taatatagcc tcttttgttc catggctttt tactgaacca tcttgtagaa
     5461 caattatttc atcagctaac tctaatattc tttcttggtg agaaattatg attatagtct
     5521 gattagactc ttcatgtatt ttcttaaaac tttcattgag ttttccaaag ctccaaaggt
     5581 ctatccctgc ttcaggttca tcaaatatag aaacctttaa atctctagca aaaagagttg
     5641 ctatctcaat tcttttcatt tcccctccag aaagagagtt atcaacttca cgatttaaat
     5701 agtcttttga acacaatcca acatctgtaa ggtattggca acatacatca gtagacaatg
     5761 gttttccatg agcaagtgta agtaaatttt caactgtcat accttttatt cttggtggtt
     5821 gttgaaatgc gtatcctatt cctttttttg ctctttctgt aatactaaga tttgttatat
     5881 cttctccatc taaaattatc tgaccactcg tagctttttc aattcccata ataagcttag
     5941 caattgtaga ttttcctcca ccatttggac ctgtgataac aataagtttt cccctctcaa
     6001 atgaaaggct aacatcattt attattccta gttcctcatt gttagactca acattaaagg
     6061 aaagattttt tatttcaagc ataatacccc tcttttctat aaaatattac attaatatcc
     6121 attcttttat tatatcagta atttttatat atcagcaact ctaagcagat aaaatgtata
     6181 ttaaataata aaacaaagtt attgaaaagt aaaaaagatg agttttatgt aaactcatct
     6241 cagaaattta gtatatcaac ttatatgtat ttaaaattta accttctata tactctaata
     6301 ttattttttg attatctttt aacataattt cttctttttt agattctatt ccattctttt
     6361 ttatctttac ctcagctaca aaggcatcat taccttcaac catttctaat agttcatacg
     6421 cttttttacg acctatttta gttgctatat cttttagtac tgccattttc ttaaacattt
     6481 tatcacctct actcaaaatt tacacttaat ttttaattat ataattctaa tcctagacta
     6541 gtttataata attattgtct ctaattatat cagatattga gtaaatttaa tactttgtaa
     6601 aattatttat cctctctgac taaataatca tttccatctt ggtctttaaa agaaaacatc
     6661 cttccatatg gcatctccat taattcccca acttcaacct cgttatttgc catttgttca
     6721 taagttccat taatatctct tgtacttaaa attattgatg gatgagatac atttatctct
     6781 ttgttttgct tcatcattag atttttatca tacaacacaa atgttgtaaa ttcattttta
     6841 cttggtgcta cttccaccca tttcatattt ggacccattt ccttttcata agttactaca
     6901 aagttcaatt tttctgtcca aaacaacttt gcatcctctt gattatttac atagagagtt
     6961 atttttccta ttttatttat cataacaata cccaccttta ttattaaata aatacctaat
     7021 attttttata tttaataata tacccatata tattattttc tatagatata tatttctaat
     7081 atttatcgcc aaattatgta attctgctca atatataatt tataatatcc atactattat
     7141 agcctttatt tatgtaattt aataacctta tatatcatac ttataattat gataataact
     7201 acataaaaaa tcacttctaa atagagttat ccatctaaaa gtgatttcat atattctatg
     7261 caactttgtg ttttagccac tttgttcctc ttaatcttaa acaatataaa gtccctctaa
     7321 caagccaatc agtatacata cctatccaaa ttcctaacac tccaaattct aatacaaccc
     7381 ccaatacgta acctgtaaaa attctaaaaa tccacatacc tattactgca gtcatcattg
     7441 tatatctagt atcaccggct ccctttagcc ctgctgataa tacaaaggat ataggccata
     7501 ttaccatagc taaacaatca cttcgaatta attgtgttga gatgtcaatt acactagcat
     7561 tttgagtata catacttgaa atccagggtg caattggtat aaatatagct cctactataa
     7621 ataaacaaat tgttgcaaat ttagttaaat ataataaagt actcttagct cctttaatat
     7681 ctccacgtcc tatatactgt cccaccaaag ttgtagcaga caaagctaaa gcattcccaa
     7741 ttacatttat tatggatgca attgacattc ctattgcatt ggatgcaatt gctgatgttc
     7801 ccatagtaac tataaatact tgaacaatca atttacctgc attaaaaagt agttgttcaa
     7861 ctccagctgg tatccctata ttaaatatag acttttgagt ttcaacatca atcttaaatg
     7921 gaaatatttt acccatagat ataaattcat ttcctttaaa taaagctctt ataattacta
     7981 tacatccaat tattctagct atagcaatag atatagctgc acctgttatg ccataggatg
     8041 gtgtttgcaa atttattcct agaggattta aatcaatacc atatataagt atatatccta
     8101 atgttacatt tactatattc ataaacatag tcacatacat aggtttcttt acatctccac
     8161 accctcttaa aataccattt gctatttgtt gtgtcgcaat aaatggatac gtaaataatg
     8221 taaactctat gtataatttt gcatttgatt ttaccaattc ttctgctgaa ccataaaata
     8281 aattaattac accagttcta aaaacccaca tcaatattgt tattgtaaag gataatatta
     8341 ctccagacac tagagcctgc ttaatagttt cattcacctt ttcactatct ttttttccta
     8401 tttgttgagc tacaacgaca gtagctccaa cagataatgc agcaaataca gatataaata
     8461 tattgtttat tgaatcaacc attccaactg cagatacagc ttcttcccca atatgacctg
     8521 ccattattgt attaaatact cctaaaagca tgacaaacgt ctgctctatc attataggaa
     8581 ttgctaactt tataacattt ttccttataa acatccctat tcctcttttc cctctttata
     8641 taaatttaat ttttaattag tttatcgaac tgtaaattga caatgcaaag tttagaattg
     8701 tattgttcgc attataatat actgctttca aataatataa atcttgttta atatcatttg
     8761 aacacagtat atctttataa ttatcttatg tttattattt tttatggata ccacatttaa
     8821 aatatttatt aatttaatat aaatattttc cgttattatt aaaagtagct atatttcgtt
     8881 aatattgtat cactatcgtg tagcaataac aataagtaca ttttatatat tttttataat
     8941 attatttaat catccaaact tttaccactt tttcaatata taaaatatta cactttagat
     9001 gtaacaaaat cgcatccatt taaatattgt attttataga ctaattttag gatgtgatac
     9061 tttggttaat ttaaatgcaa ataatctaaa tgtaaatatg gtttatccta tttcttccac
     9121 agcacccata cgtttcagaa gatatactgt ttcatattta gaaaacatgg aaaatattta
     9181 tttaactata gcaacatact ttgatacact tggtttaggc acaatgaata tcgacaaagt
     9241 ttatggtcaa tgggcttggt ttactgataa tatatatgat ttaaatctat ttgtttttgt
     9301 aggaaattat ccttatcaaa ttgctaaaaa cagatatgat acatttgtag atattttgcc
     9361 agtagctatt acttctattg tcaatggaga tagagtattt ttaatttcaa atccttgttt
     9421 gttaaattca aaaattacag ttagatttat atctagtcat cctactctta atagaacagt
     9481 tgattatggc aatattagag attttatttt ttaaaactgc aacatgatgt gctattaaaa
     9541 aataccctaa atttaatgat attattaaat aactagaata tttttaattg gcacatcatg
     9601 cctagctatt ataaattcat aatattattt tacttaagat aagtactgta ttttatctac
     9661 ttgtatattt ttatttacct agtttctcag ttctatatcc tatttcttta ttagctagct
     9721 tataaccttc ttgtatcatt tcttctctcg ttaatgcact ccctaataaa ttgtcaatac
     9781 tcagttgctc tctatcacta aaatacttat ccaataatga ttcctctata tcttcctgat
     9841 atgccaaatt tccttcatgc attatatatt ttacatcgaa accttcttta tttaatactt
     9901 ttcccaccaa aatacttcta tgacatctta taggttcttg catagctcct aataaaacta
     9961 tcctataacc catttgacaa ccctttttta atctttctat tccgtttaaa aaaatatctt
    10021 cttttgctac tttctcaaaa tctgcataac cttcttgcgt atatacatct ttattatttc
    10081 ttttagctcc aaattctttt cccatgtata tatatataaa tccggaattt ctaagagatt
    10141 cgttaaatgc ctctttattg tattgaatat tatatttaga atatggagtt tctctaatgt
    10201 caactacaca atttatgtca tattttttta tcatattaat aagcttatca tatggataat
    10261 ttgaatgtcc tattgcgaat atttccatat aaataccctc ctattctttg aaattagtat
    10321 ctatatatgt agatacccga tttacttaaa attaaataaa gtattacttt aaatacccaa
    10381 tatctttttt tcttgatact gtatattttt ttactttata tccttaaaaa aatatacaac
    10441 tttatatata aaacatcaat atttatatat attttgtata ttaaatacaa ttatttataa
    10501 aatctttgat aaaaatttat aaatagagca tctttagaaa actattaaca gaaaaacaca
    10561 ctaaaaattt gattatccgc taaaacactg tatctatcgg cattatcaag gagctaaaca
    10621 catcaaaata ctactaattt actacgattg aatgagcctt gatacgtcct atttcccaga
    10681 tatgcaaaga tacggtacag cacatcagta ttgaaacaag aaaaattgaa tacttcatag
    10741 actacggaac gcacaatatc agcgttcctt ttctatttcc agccgttcct agtggacggc
    10801 tattttacta ccaaaatgaa aggagcattt agaattatga aaaagatatt aaaacgattg
    10861 tgtacaggct ttcttgcctt tgcaactgtc gttaccgctt taccgagttc aacggttcat
    10921 gcgtctaata cacagtattg gacggaaagt aaagagcgtg tcagtatcgt agaacaagta
    10981 atgaatgacg gttctatcag ttctaccttt aatgagggac atttaaccgt tgagggtgag
    11041 gacgcttatt gtatcgacat caacacagcc tttaaaaacg gctataagac caaagctgac
    11101 gcaagtaccc gtatgagtgc cgaccagata gctgacgtcg ccttatctat tgagtatgtg
    11161 aaacagtaca cagacatcca cagcggaata agcagtaaac acgcctacct attaagacag
    11221 cttgttgtct ggcagagatt aagtgttcag cctgactggc aatgggataa tgtgcgagct
    11281 tcctatgatg aaatcccaaa agccgtacaa gatgaagtat tcgcaggagc aaaagccttt
    11341 gtgaaagaaa acaaaggacg ttatgactgt ggcggatata tctactctgg cgagggtcaa
    11401 gagttagggc aattctgggc gaagttagct gtcggaaata ccaaacttca aaagacttcc
    11461 accaatgcca atattacaga cggcaacggg atttattcaa tcgctggtgc aacatacggt
    11521 gtgtattctg ataaagactg cacgaaacag cttaccaccc ttacgactga tactagcgga
    11581 aatacagaag ccgttgaagt aagagccact atagtatata tcaaggaact ttctgcacca
    11641 gcaggattta aaattgataa aacagtttac tctttatctg tggaagttgg aaaaacagcg
    11701 actttaaaag tatctgatac accaaaagta acagatacct tgattgagct attcaagatt
    11761 gacatggaaa cacagaaatc caatccgcag ggaaacgctt ctttagaggg agcagagttt
    11821 acatggaact tctacgctgg atattacaac aaaaacaatc ttccagcaca gcctacaaga
    11881 acatgggtaa caaagactat cgctgaaaaa gacagcgacg gtgctatcca ttacattact
    11941 cgtttagctg acaaatataa agtatcttgg gacagcttct atacgcagga cggtaaaaac
    12001 gtacttccat taggaacact aactgttgag gaaacaaaaa gtccgtcggg ttacttgtta
    12061 gagggtacat atatgcaggc tgacggtagc gaagaacaga taaaaggaat gtatctgaca
    12121 cagattacag aggacggcga ccttgccgta ttatctggaa gcaatcaata ccatgtttct
    12181 gataaagtca ttcgtggcgg tgtgaaaatc cagaaacgag atttagaaac caaagacacg
    12241 aaagctcaag gcggtgcgac tttgaaagat accgcctttg aaatcatttc cttaaatgag
    12301 aatgccgtct tagttgaggg caagttatac aagaaaaatg aagtgttaaa gacaatccat
    12361 accgacattg agggtatcgc ttctacttct gctgacctat taccttacgg aaaatacaga
    12421 ttgtctgaac aaaaaccgcc agagggatat ttgactgacg gtgcaaagcc gattgatttt
    12481 gaaatcacag aaaatggaaa aatcgttgat ttgactgacg aagcccactc tatctataac
    12541 cagattaaac gtggcgatat tgagggcgta aaaattggtg caggttcgca caagcgtctt
    12601 gcagatgttc cgtttaggat cacaagcaag acgacgggcg aaagtcatgt tgttgtaact
    12661 gatgataacg gacaattctc tactgcttct gattgggctt cccacaagca caataccaat
    12721 gcaggaaaaa caagcgagga cggtgtgtgg tttggtactt ctgaaccaga cgacagcaaa
    12781 ggtgcgttgc tttatgatac ttacatcatt gaagaattac gttgtgaaag caacaaaggt
    12841 ttcaaactta ttccaccgtt tgagattgtc atttccagaa ataaggttgt ggttgattta
    12901 ggtacgctga ctgatgaata cgaaaaagaa atcactatcc atactactgc taccagcaag
    12961 gacggcgaaa agactattct tgctgggaaa gacgtaacta tcactgatac agttaaatta
    13021 gacggtctta ccaaagggac aaaatatcag ttgaaaggct ggcagatgtt aaaagaagaa
    13081 aatgcagagc ttatcatcaa tgacaagcgt attgagaatg actacatctt tacggctgac
    13141 agcgaaacta tggaagttaa aatcgagttt acctttgacg cttccaatct tggcggtaaa
    13201 cagcttgtaa cttttgagga attatacgat ttaagcaatc cagacgaacc tatcaaagtt
    13261 gcggaacaca aggacattga ggacgacgga cagacagtta ctatcaagga agtaccagaa
    13321 acacctaccc cagaagaacc agagaagcca accacaccag atacacctac gaaaacagac
    13381 agtcccaaaa cgggcgacaa tacaaatatc cttgcctttg caattatgat gtttgtttct
    13441 gctggtgggc tggctggtac atactttttc aaacaccgta agatgaagaa atcataaggc
    13501 ggtagctgta tgagaaaaga aaaatcacgc tctccgccat agcttagata ggcagactat
    13561 acctattctg gcttgtctgc cgattacctg caagaacacg gatagtcaag ggtgcgttag
    13621 catttattta ccctttacta tctgggggct tgctggcact ttcctaaatg ccagaataca
    13681 cacatcaatc aaacttaaag taagaaacga ggtaaaataa tatggaatta aaatatatcg
    13741 tgccgaatgt ggcacagact tttggaaact tggaatttgc aggggaaaac aaagtagacc
    13801 agcaacgtat caatgggcgt tacactctcg tatcaagaag ttacaacttg tattcggata
    13861 ttcagagagc cgacgacatt atcgttgtat tgcctgcaaa agctggcgag aagcatttta
    13921 agccagagca gaaagtaaaa ctgattaacc cacgcattac cgcagagggt tacaacgtca
    13981 aaggacgtgg atttacaaac tacattttaa tggctgatga tatgttacca gcagaaagca
    14041 aataaggggg tatttgatta tgagattaac aaatggaatt gtattagata acgaaaaaac
    14101 ttttggagta ttgaaattct ctgcacttcg acatgaggtg cgtgtagaaa atgaggacgg
    14161 aacgacaagt gatgaaatta agcgtcgtac ttatgatttg aaatgtagtg tgcaggaacg
    14221 catgatacaa gtgtcaatcc ccgctgatgt tcccgtaaag gactttcctt ataatgcgga
    14281 agtggagtta atcaatcccg tagctgatac ggtggcaaat gccaacttta gagggactac
    14341 ggttgattgg tacatcaaag ctgatgatat tgtattgaag aacaaaggcg gtcaagctgg
    14401 aaatccgcag aacaacgctc cgcagggaca gcagaaaaag taagctgaca aactagtttt
    14461 tcattgtagg agatataaac aactgttata atatggatgt ggaaacagtt aatttagact
    14521 tataaaggag aaatgtgtat gctagataaa atacctaatg cagaggaaat gactgctttg
    14581 gtcggacaat cattatatag tgtatggaat gaattgtgtg ccttgattga tgaaaagtat
    14641 gaaatggaat gtctatggaa taaaggtggc aaagcatgga attatgaata taagtatcgt
    14701 cgaggtggca aaacattatg tgccttatat gctagagaaa attgtgtggg atttatgatt
    14761 atcttaggta aagatgaacg gttaaaattc gatacatata gagataatta ttcaaaagaa
    14821 gttcagagaa tttatgatga aacaaaaact taccatgacg gaaaatggct gatgtttgag
    14881 ccaacagata caactttgtt tgacgatttt gttaaacttt tgaggataaa aagaaaacca
    14941 aatagaaagt agtttattac cacaccatta gcaaatggat agtttcttat aatagcggat
    15001 atatgaaaat gctgtcatgt ggacataaag aaaattggaa gttgtggagg tagcaaaaat
    15061 gaaattaaaa aaccctatgt tggtagtaac tgatatagat aaatcagttg agttttataa
    15121 aaaggttttt ggactttatg tcattatgga ttttggggca aataaaactt taacaggtgg
    15181 attagcctta cagacaagtg aaacatacaa agagtttatc ggtacaagtg atatttcttt
    15241 tggtggtaac aattttgaag tctattttga agaagaagat tttgataaat ttgctgatag
    15301 gctgaaagaa tatgatattg aatatgtcca ccctattata gaacattcat ggggacagcg
    15361 tgtagtccgc ttttatgacc cagataaaca tattatcgaa gttggagaaa acatgaagat
    15421 agtgtgcaag cgtttcttaa atagtggaat gacaccagaa caagttgcag aacgtatgga
    15481 tgtacctatg aaatttataa atgcttgtat gcgataaatt gaaagttagg agactaatac
    15541 tatgaaagga tttgaacgca aaaatcaatt attttctctt tgcggattga attgcggact
    15601 atgccctatg cttttgggaa attactgtgg cggttgtggc aatggtaatc aatcatgcag
    15661 aattgcaaaa tgtagtcttg aacatggaca gattgaatat tgctatgaat gcaaacaata
    15721 tccatgcgaa aaatatcaac acattgatga ttatgattct ttcatcacgc ataaacggcg
    15781 aaaagcagat ttagaaagag caaaaaacat aggcattgag caatataatc ttgaacagca
    15841 ggaaaaaaca caaattcttt cttacttact ttctaactat aatgacgggc gtagaaagac
    15901 tttcttttgt gtggcagtca atttattaga actttcagaa ttacaagaag caatgaaaca
    15961 aatacaatcc aatgacgaat tgaccttact accatttaag gcacaatgct tgtatgtggt
    16021 ggaggtgttt cagaagattg ctgaaaggag aaatataaaa ctgaaacttt tcaagaaaaa
    16081 gtgattttca aatttgaaat tgtaacaaag attatttata tgacgaatgg gggaatacct
    16141 ttggaaacag tagagttaag atttcaatat actcaaagtg aatatataaa agcagaaagg
    16201 caatatttaa tttctagtaa aactatacat aaatatgata ttgctttagt cgctgtattt
    16261 ttgttgctgt cagtcgttta tatgctgttc tcctctttta gcgtatttag tattttaata
    16321 tttggattga taattgttgt aactgcattg ggaagctatt tatatatcct aatgcctata
    16381 ctgaaattca aacaaactgc aaaatatcat gaggaatata cgctggtatt ttctaaggaa
    16441 aacattaaat ttaaaacaca aagcattgac tcagaagtga agtgggacat ttactctgca
    16501 ctatgggaaa gccatgattt ttattactta attcaagcac cacgattata tacgttaatt
    16561 cccaaaagaa tttttaaaga cctaaacgaa aaacagctat ttgaagaaat tgcacaatca
    16621 agagttaaaa caacaaagca tatataatga acatacccta caatgtaaca acttcatatt
    16681 catacacaca aagcggttag tcttttaaga ttgactgctt ttttcatact taaattaaga
    16741 ttggagtgat tgatttatgc gaatgatttt gaataaagga caccgtatca gagccagaga
    16801 caagaacctt gtctaccact tttccatagg gacgcttctg tttgtatttg tggcggttct
    16861 cctgctactg aatatcaaac agctcatgcg taccgactgg gaacatttca gcttattgga
    16921 caatggcttg acgctttccc cctacaactt cataaccata ttgatagcga ctggtatttg
    16981 tgcattggtc gcttttctgt attaccgctt ctgttatgac agtttcaaaa agctcctgca
    17041 ccgtcaaaag ctggcacgaa tgatactgga aaacaagtgg tatgaagcag ataccgtaca
    17101 agacagcggt ttttttactg acctgcaaag cagatcaagg gaaaaaatcg tctggtttcc
    17161 aaagatttat tatcaaatgg aaaacggatt gcttcatatt cactgtgaaa tcacattagg
    17221 aaaatatcaa gaccagcttt tgcgattaga ggataagctg gaaagcggtt tgtactgtga
    17281 gctgaccgac aagaccttgc atgacggcta tattgagtac acgcttttat atgacatgat
    17341 agcgaaccgt atttccattg acgaagtgaa agcagaaaac ggctgtctta ggctgatgaa
    17401 aaatcttgtc tgggaatatg acgtactccc tcacgctctg atagctggtg ggactggtgg
    17461 cggtaagacc tactttctgc tgacgcttat tgaagctctg ctacatacga atgctgtcct
    17521 ttacatctta gacccaaaga acgctgacct tgcagactta ggtacagtta tgggaaatgt
    17581 gtatcatacc aaagaagata tgattgattg tgtcaatgcc ttttatgagg gcatggtaca
    17641 aagaagcgaa gaaatgaagc aacacccaga ctataaaacg ggcgaaaact acgcctatct
    17701 tggtttaccg ccctgctttc ttatctttga tgaatatgtg gcgttttttg aaatgctggg
    17761 gacaaaggaa agcgtaagtt tacttagcca gttaaagaaa atcgttatgt tgggacgaca
    17821 agctggatat ttccttattg ttgcctgcca gcgtccagac gcaaaatatt tctcggacgg
    17881 tatcagagat aatttcaatt tccgtgttgg attggggcgt atcagcgaat tgggttacgg
    17941 tatgctcttt ggttctgatg tgaaaaaaca gtttttccag aagcgtatca aggggcgtgg
    18001 ctattgtgat gtgggaacaa gtgtcataag tgagttttac acgcctttag tcccgaaagg
    18061 acatgatttt ttgcagacca taggctctct tgcattcgta aggcaggacg ggacggcgac
    18121 gtgcgaagcg aaaggcgacg gcacggacta gccgttgctg gtgtggcgtt agccacgcca
    18181 gcagatataa gcccctcatt atctaacaga ggggcacaat tacgctggaa actggttcaa
    18241 aaaccttgaa aagtccgcta ggaataagga ttttcttagt ttttagctag ttgtgataat
    18301 cacttgaaaa tatcacaaaa tcacaacaat atcacgattg ggggtatgac aactgaatga
    18361 tactgatttt ctgaacacct tgaaagcaaa acgcagtgat tatggcgtat cgcagacaag
    18421 gcttgcaatc atggctggta tcagccgtga acatctaagc cgtatcgaag ctgggaaggt
    18481 agcactgacc gaggatatga agcacaaact actggaagcg gtggaaaaat tcaatcccga
    18541 cgctcccatg ttcctgctct ttgattatgt gcgtatccga tttcccacgc tggatataca
    18601 gcacgttatc aaggacattc taaagctgaa tatagattat atgcttcacg aagatttcgg
    18661 gcattacaag tacaccgagc attactatat cggggacgtg ttcgtttaca cttcacaaga
    18721 caaggaaaaa ggtgtcctgc tggaactgaa aggaaaaggc tgtcgtcagt ttgaaagcta
    18781 tctgctggca caggaaagaa gctggtatga cttcctcatg gacgcattag ttgatggcgg
    18841 tgtgatgaag cgtatcgacc tagctatcaa cgacagaacg ggcttactgg atattccaga
    18901 actgatagag aaatgcaaga acgaggaatg tatttctaaa ttccgtagct tcaagaacta
    18961 tggttctggg gagctggtaa agcacaacga agccaacaag gacggcatgg gacatacgct
    19021 ttacattggt tcatttacca gtgaagtgta cttctgtgtc tatgaaaaga attatgaaca
    19081 atcctcaaaa ttagggatac cgattgagga agtccccatt aaaaaccgat ttgagatacg
    19141 tttgaaaaat gagcacgcct actatgccat tagagagctg ctgacccact acgacgcaga
    19201 gctgacggca ttttctatta tcaaccagta tatccgcttt gccgataagg aagccaacaa
    19261 gcgaaaaagc gactggaaaa ccaacgcccg ctggtcttgg ttcattggcg agggacgacc
    19321 gcccgtgaag ctgacgacaa agccagagcc ttacactctg caaaggacgc tgaactggtt
    19381 acaaagacag gttgcaccga ccttgaaaat gctgaaacag atagacgctg gcaatcagat
    19441 ggactatctc aagaccattg aacagcaggc aaagctgaca gataagcaca agcagataat
    19501 cagacagcag acggcttcgg tggacgaact gatagaaaaa gaaaaggagt gattgatgat
    19561 gtgggaattg attaaggact tactgctggt atcacttggc atgggtatcg gcgtggttct
    19621 gatgtgtatt atgagtgtcg gaaaggaagc tgaccgacac atgattgaat taaaagaaag
    19681 cgaggaaaaa taaatgaatt tcgggcaaaa tttatataca tggtttttaa gcaacgccca
    19741 gagcttagtg cttatggcga ttgtggttat tggtatctac ttagggttta aacgtgagtt
    19801 ttcaaaactt atcggcttct tggtggttgc cttagttgct gttggattgg tattcaatgc
    19861 aggcggtgtc aaagacgtac tcttagaact attcaataag attatcggcg catagccgta
    19921 ctttttcatt atggtttgcg gatacgcaaa catacctttc ccactttggg agtgggctaa
    19981 ggggaaaggg ggtaacggaa tggtacacag ataaaaatac agcataatga atttcattgc
    20041 ttggctcaaa catagttgat ataataaaga tatgaaaata ataaacgaaa gtttttttga
    20101 taaggagtga tattgtgaaa ttgtgtattg ttttatctcc atataaggct taatggaata
    20161 gacttgtatg gagtgaaatg ttatccagag agccttacat tttatcaaat ttcaaaatgt
    20221 aaaggagaat gggcatggaa tataaatata caaaaattga tttgaataaa tggaatagag
    20281 gtaaattgtt tcaaagctac attgataata tgcgtattgt tatgagctta accgtagata
    20341 ttgatgtaac aaagtttatt gaattttcaa agaagcatga tttaaaattt tatccagcta
    20401 tgatatgggc tgtttcaaag gttgttaatg aacatgatga gttcaaatat agttgggata
    20461 ataatgggaa tttaattaag tgggattata tttctccgtc ctatactgaa tttcataaag
    20521 aagatgaaaa tttcacaaag atagttacag atttttctga tagcatattt gaatttcata
    20581 aacgttttat attagatagg gagaagtata aaacagaacg tgcatttgtg gaaaatcaat
    20641 ctttgaactt ttttgatgta tcttgtttac cgtgggtaaa atataatcat tttgatgttc
    20701 atgtttttga cgagggaaaa tttcttgcac cagttattac ttggggcaaa tatgaattag
    20761 agcaagaaag atatataatg cctcttacaa tgaatataca tcatgccgta gcagatggat
    20821 tccatttatc cagatttttt aatgaagtac aagaattgat aaactcaatt taacagctat
    20881 atacaaagca gttagtctat acgattgact gctttttttc atacctaaat ttaagattgg
    20941 agtgattgct tgaaagatat attttcggat atgcaggcaa gtatcggctg tacctacatt
    21001 tcagatttac cacatcataa acgtatggtg tggcaggaaa tgaagcgact gaaccttgcc
    21061 gattatccgc agaaacaatt agaagatttt gcaggctatg tctttggtgt cccttacact
    21121 agcatagctg aagcatgaaa gaaaggacgt gaaaacctat gaatgaaatg cgtgtctgta
    21181 tcgaaagccg actacacact tctgaagaaa tccgttccgc atggttcaca cttcccattg
    21241 acgaggaaga actggaagaa cagataggcg ttcctatcga cagtgaagat taccatatcg
    21301 ttgaaaagga actgcccttt gctgatgaag tcggcgaaga tgcgaccatt gaaaaactga
    21361 atgaccttta ccataccttt gaaagtctgc ctgccgattt acaagaggac tacggggagc
    21421 tgatgtgtta ctttaccagc cttgacgaac tgcaccagca ccgccatgat gtgatacatt
    21481 attcatggtg taaaaacatg gctgatgtgg caaggcattt gttggacaat gaccctgctt
    21541 tttctgccat cgaggaacgc ctgacccgtt actttgatta tgaagcctac ggacagtatc
    21601 ttgatgataa cggagaattt atagaaacag accacggtat ctatgaactg ccgtagaagt
    21661 gaggtgtttc tatggtagag gatatgcgtg tatatatcgc taatcttggg aaatacaatg
    21721 aggggtatct ggtcggcgac tggttctctt ttccgattga cgaagaagat gttgccgagc
    21781 gtatcggctt gaatgaacgg tacgaagaat acgccgtaca tgatacggaa aactttccca
    21841 ttgagattgg cgaatatatc tcgattgaag agctcaatga aatgtatgaa atgatatgtg
    21901 agcttcccga ctacatcacg gacagtttgg acgaatttgt atcaaattat ggaagtttgg
    21961 aggaactgta cgaccatagg gacgatatga ttttatacgc tggctgtgag gatatgaccg
    22021 acgttgccta ttacttcatt gatgaattgc aggcacttgg cgatattccc cctagtttgc
    22081 agaactatat tgactatgaa gcatacggca gggatttatc ctttgaggga acttttattg
    22141 aaacaagata cggtatgtgt gagataccgt ggtaagaagc tggaagatca gcgacaagca
    22201 ttgttgcttc tgacagcttt ttctattggg gacagtctga aaaacggctg tccttttcta
    22261 ttatacgaaa ggagttgaaa caaaaacgtg aaaaagatta aaagctacac gggtatctgg
    22321 aacgtggaaa aagtcttgta tgcaatcaat gactttaacc tgccctttcc tgttaccttt
    22381 acacagatta catggtttgt gataaccgag tttatcatca ttctgtttgg ggacttaccg
    22441 cccttatcca tgattgaggg ggcattttta aaatacttcg gtattcccgt agctcttaca
    22501 tggttcatgt cgcaaaagac ctttgacggc aagaagccgt acagcttttt gaaatcacag
    22561 ataacctttg ccctacgacc aaagattact tatgcaggaa aagccgtgaa actggataag
    22621 caggtactac atgaagctat tacggcagta aggagtgtga gctatgttcc cgattaaata
    22681 tatcgacaac aaccttgtct ggaacaagga caatgaggtg ttcgcctact atgagctgat
    22741 accttacaat tacagttttc tatccgctga acagaaattc attgtgcatg acagcttccg
    22801 acagctaatc gcacaatccc gtgagggcaa gatacacgct ttgcagattg ccacagaaag
    22861 ctcaagccga agcatacaag aacagtcaaa gaagctggtt acgggacgac taaaagacgt
    22921 tgcctatcag aagatagacg aacagaccga agcgttagta tctatgattg gggacaatca
    22981 agtggactac cgcttttttc ttggcttcaa gctcatggta acagaccaga gcatgaacct
    23041 aaagagcgtg aagcaatcgg cgtttctcac attcaaggag tttatccatg aagtgaacca
    23101 cacgctgatg aatgactttg tttccatgcc aaatgatgaa atcaaccgct acatgaaaat
    23161 ggaaaagctg ttggaaaata aaataagccg acgcttcaaa gtaagacgct tagataaaaa
    23221 tgacttcggc tatctgattg aacacatcta cggcagggac ggtgtcgcct atgaagatta
    23281 tgagtatagc ttaccgaaga agaaactgaa aaaggaaacg ctgataacgc attatgactt
    23341 gatacgtccg acccgttgcc ttgtggaaga aagccagcga catttacgct tggaacatga
    23401 ggacagcgaa agctacgttt cctactttac tgtcaatgcg attgtcggcg agcttgattt
    23461 tccgtccagt gaaatcttct atttccagca acagcagttt acttttcccg ttgataccag
    23521 catgaatgta gaaatcgtgg aaaaccgaaa agcgttatcg acggttcgca acaagaaaaa
    23581 agagctgaaa gatttagaca atcatgcata ccagtctggc agtgaaacca gctcaaatgt
    23641 ggtagacgca ttagacagtg tggacgagct ggaaacggat ttagaccagt ccagagaaag
    23701 tatgtataag ctctcttatg ttatccgtgt atctgctcca gaccttgacg agttgaaaag
    23761 acgctgtgat gaagtcaaag acttctacga cgatttgaac gtcaagctgg tacgccctgc
    23821 tggcgatatg ctggggcttc actctgaatt tcttcctgcc agcaagcgat acatcaacga
    23881 ttatgtgcag tatgtcaaaa gtgattttct agctgggctg ggctttggtg cgacacagca
    23941 gttaggggaa aacacgggta tctatatcgg ctattctgtc gatacgggac gcaatgttta
    24001 tctacaaccg tcccttgcca gtcaaggcgt aaaagatacg gttactaatg ctcttgcttc
    24061 tgcctttgta gaaagtcttg gcggtggaaa atcattctgt aacaacctgc ttgtctacta
    24121 ctctgtgctg tttggcggtc aagcggtaat cttagaccca aaatccgagc gtggcaactg
    24181 gaaagaaacg ctcccagaaa tcgcccatga aatcaatatc gtgaacctta ccagcgacag
    24241 agaaaatgca gggcttcttg acccgttcgt gattatgcag aatgtgaaag acgctgaaag
    24301 tctggcaatc gacatactca cattccttac gggcatttct tcaagggacg gcgagaagtt
    24361 ccccgtactt agaaaggcag tgcgtgccgt tacccagagc gaccagcgag gattgctcca
    24421 tgtgattgag gaattaagaa aagaagatac acctatctct tgcaatattg ccgaccatat
    24481 cgacagcttc acggactacg actttgcaca tctgctgttc tcggacggta cggtgcaaaa
    24541 tgcaatcagc ttagacaacc agctcaatat cattcaagta gccgacttag tgctacccga
    24601 taaggacacg acctttgaat tactgtccgt ttccatgctg attgtgatta gtacctttgc
    24661 gttagatttt atccactcgg atagaagtgt tttcaagatt gtagaccttg acgaagcatg
    24721 ggcgttctta aatgtggcac aaggcgaaac gctctctaac aagctggttc gtgctggacg
    24781 tgccatgaac gcaggcgttt attttgttac acagtcctct ggcgacgtgt caaaggaaag
    24841 tctgaaaaac aatatcggtt tgaaatttgc ctttagaagc accgatatta acgaaataaa
    24901 acagaccctt gaatttttca gcattgacaa agaggacgag aacaaccaga agcgattgcg
    24961 tgatttggaa aacgggcaat gcttgcttca agatttatac ggacgtgtgg gcgtggtgca
    25021 gatacaccca gtctttgaag aattactgca cgcctttgat accagaccgc cgatacagcg
    25081 aaatgaggtg gagtgatgaa agaaaggata aaaagtgtgt tcacaagaaa aaagatattc
    25141 cgctttctca aaatggctct gtttgtcgtg gcactttccc ttatcctgct ttcacttttg
    25201 ggaacggtgg cacacgcaac gggacttgtg gacgacacta tcaacaccga gaacctttat
    25261 tccaaatatc cgctgtcgaa ttatcagctt gatttctatg cagataataa ctgggcgtgg
    25321 ttgccgtgga actggctgga cgggattgga aaaagtgtgc aatatgggct ttactgtatt
    25381 accaactttg tctggacgat aagactatat ctaagcaatg caacgggcta tgtagtgcag
    25441 gaagcctaca agctggactt tatcaacgat atggcagaca gtatcggaag aagcatacag
    25501 acccttgcag gcgtaactca aaatggtttt tctacttcgg gcttttatgt gggatttctt
    25561 ctgctgatta tcttagtcgt aggtatctat gttgcctata cgggactgat aaaacgggaa
    25621 accagtaagg cactacacgc cgttatcaac tttgttgtgg tgttcgtatt atcggcttct
    25681 tttatcgcct atgctcctga ctacatcaag aaagtgaatg acttttcatc agacatcagt
    25741 accgcttcac tggacttggg aacaaaaatc atgcttcccg acagcgacag caagggcaag
    25801 gacagcgtgg acttgataag ggatagccta ttttccatac aagtacaaca gccgtggcta
    25861 ctgcttcaat ttggtaattc gggtatagag gaaatcgggg cagaccgtgt cgaagctctc
    25921 gtatcggcaa gcccagagga cgaggacggc aagaccagag aggaagtcgt gaaaacagaa
    25981 atcgaggaca acgacaacaa caatctgacg atactgcagg tggtaaaccg tttaggtatg
    26041 gtgttcttcc tcttgttctt caacttgggt atcacgatat ttgtattctt gcttacgggt
    26101 atgatgttgt tcagccagat actttttatc attttcgcta tgtttctgcc tatcagcttt
    26161 ctattaagta tgataccgag ctatgagagc atggcaaaac aagccatagt ccgtgtgttt
    26221 aatacgatta tgacaagggc aggtattaca ctgattgtca cggtagcctt tagtatttcc
    26281 agtatgttct acaacatatc gacggactac ccgttcttta tggtggcgtt cttgcagata
    26341 gtgtattttg caggtatcta catgaagctg ggcgatttaa tgagcatgtt ctctttaaac
    26401 gctggcgaca gtcaaagcat gggacggcga atattccgca gaccgtatct gttcatgcga
    26461 catagggcta gacgtatgga acataggctt gcaagagctg ttagtgctgg tggtgtcgct
    26521 ggtgcggtgg ctggtggtgt cgttgccagt tcaaaatcta cacgccagaa tggaacaaag
    26581 aacaatcgtg gaaatacaag ctccagcatg gggcagaaag caggttcagc cgtgggagct
    26641 gtccttgata caaagaataa ggtcaaggac aaggcaactg ctgtcaaaga aaatatcaaa
    26701 gatatgccga cacagactgc ctatgcggtt cactctgcta aggaaaaggc gaagtccagt
    26761 gtgtctgatt tcaagcgtgg cgtggtgcag gaaaaggaaa accgccagtc tggacgctta
    26821 aagaagcaac agctacatag acagaatatc gctgacaagc gtatggaact tcaaaaggca
    26881 caagaatcaa ggcaggcagg taagaaaacg gacggatcag cgacaagcgg agctacccgt
    26941 ccccatgaaa gaccagctac cacttctaag gttaatgtag aaaaacagca ggaagtcaaa
    27001 cgccctgcca tagcttcaac cgtgaagaat gatgaaccta tcaagaaaaa tgttgtcaag
    27061 gaacgtccac tatcttctgg cgatacatca gcaaagaccg tcaatcaaga aaccacaaga
    27121 cagaattaca agactgaccg tgttacgaaa acaaccgttc agaagcatac acagcagaat
    27181 accgagaaga acaaacgaac cgtattcaag aaaggacaaa agaagaaatg aaactaagac
    27241 atatcgctat tgttggcagt ctgttttcta tcctcttttc tctcgtatta ttctttgggg
    27301 ttctgattag tgccgaggac gacgacgggg gcaatggtta ttcctctaat tatgtaggta
    27361 tgaacctatc tgccgaagtc ttgaaacatc agcctatggt agaaaagtat gccaaagaaa
    27421 acggtatttc cgagtatgtc aatgtgttgc tggtaatcat acaagtggaa agtggcggta
    27481 cagccgagga cgttatgcaa agctctgaaa gtctgggact accacccaac tcactagata
    27541 cggaaagctc aatcaagcag gggtgtaaat attttgcgtc cctgctttct tcctgcaaaa
    27601 atcaaggtat cagtgatata aatgttgtga tacagtccta taactatggc ggtggctatg
    27661 ttggctatgt ggcaggaaac ggaaaaaagc atatgttcaa ccttgcggaa aacttcgcaa
    27721 gggataagtc gggcggtcaa aaagtaacct atacgaaccc tatcgccgtg gcaaaaaatg
    27781 gtggctggcg ttatggctat ggaaatatgt tctatgtgga gcttgtgaac cagtaccttg
    27841 ttgtcaatca agtatcgggc gagctggcac aaaaggttat gaatgaagcc ttaaaatatc
    27901 aaggttggaa gtatgtatat ggtggcagta acccgaacac ttcttttgat tgttcgggac
    27961 tggtacagtg gtgctacaac aaagctggcg tatctttacc gagaaccgca caaaatcagt
    28021 atgacgcaac ccagcatatc ccactatcgc aggcaaaggc aggcgatttg gtctttttcc
    28081 acagtaccta caatgcagga agctatgtaa cccacgtcgg tatctatgta ggaaacactc
    28141 agatgtatca tgcaggcgac cctatcggat atgccgattt aaacaatgct tattggcaac
    28201 agtacttgat ttgtgctgga agaataaaac agtagaaagg attggaaacc atgtttaaaa
    28261 agaaagaaaa accagtaaaa gaaacgaaag tccgcactat gaaagtaggc acacataaga
    28321 aatctgtgat tgctctgtgg gtggtgctta tcgccagcgt atcatttggc gtgtataaga
    28381 actttaccgc cattgatatg cacacggtac atgaaacgga aaccattcag ttaagactaa
    28441 atgacaccaa cggagttgaa aattttgtga agaacttctg taagtcctac tacacatggg
    28501 acaacagcaa ggaagctatc gaagcaagga cgcaggcaat cagcaactat ctgacaaagg
    28561 agttgcagga cttgaacctt gataccatta ggacggatat accgacaagc tccactgtta
    28621 caaatgtact gatttgggat ataaaacagt ctggaacgaa cgattttatc gctacctacg
    28681 aagtagatca gcagataaaa gagggagaac agacaagcaa tgtcaaagca acctataccg
    28741 tcaaagtcca tgtggataaa gacggcgata tggttatcgt acagaaccca accattgcac
    28801 cagcgattga aaaatcagac tatgagccaa aggcacaaga agccgacgca agcgtggacg
    28861 cagataccgt caatgacgct accgcatttt tggaaacttt ctttaagctg tatccgacag
    28921 caacagaaaa agaacttgcc tactatgtgg ctggcaatgt gcttgaacct atcggcaggg
    28981 actacctcta ttccgaatta gtcaatccta tgtttacgga tgacagggat aatgtgaaag
    29041 tcagggttgc ggtgaaattc attgataatc agacaaaggc aatgcaggta tcacagtttg
    29101 agcttgtgtt acataaggat agcaactgga aaattattat gtaagatatt ttgttggcag
    29161 gctctatttt cggatatagt ctgccttttc tatagcaaat gtgctgcact aacaagcgat
    29221 ttcattgtat tttaagcaat taaatctttc ttgacaattt tatcttaaat catatattta
    29281 tggatattga ctttctgctt gcaataagtt ataatatgac tataaaacta aattagtcat
    29341 ataggaggcg tgtggtatgt ataaagaagt tggtatttct tcaaataatg ttccgataac
    29401 actttctatt tggtatacag aaagaaatag tcctaccatt gtttttttgc cgggtactat
    29461 gtcacaccct ctcatgtatg agaattttct atgtggtttg agtgaaagag gatttaatat
    29521 aataggcatt cactatcttt cacacggaaa aagccctaaa atcaaaaaaa attatacaat
    29581 ggaagatttg ctgcataatg tatatgacgc aacgacttac ggaatagaaa attttggtga
    29641 aaacatagct gtcatgggtt ccagtcaagg tgggatttta gctgcaatgg cggcgggtag
    29701 ggacacaagg ttaaaagccg tttttccaca taatatcatg ctgactacat taaaagaaac
    29761 tatgagctta acaaaatacc ccgcatggtc acaccgtttt atggggctga tacagttggg
    29821 ctttcgtgta ggtggaaaat tgctgcctaa ctataaggtt ccaggagacg cttatttaga
    29881 ctatgacaga gtattttata gtgaacaggc aaaacaagat tgcttaaatg accctatgct
    29941 tttaccctat tatcctttaa gatttgtcgc cagcttattt aatgctgact tatcgtgctt
    30001 ggagaatggg gctatacaat gtcctgttat tttaattact gccaaaggcg atccgctttt
    30061 tagatttgat tataccaaca aagtatttga tttaattcat gtaccgaaaa aggaattact
    30121 tactttagag cttaatcgtc acatgatttt taatgaggac acggacacta caataaacgc
    30181 attggaagct accttgcata aatatcttgg atagtatatt gattatataa tcagtaaatg
    30241 ttatactttt catgacgata aaaacatttt agtcataagg gggttatgag tttgccacga
    30301 tttacggaac aagaaaaaga aatcataaac agtaaacttt tgatagaggg agaaaagctg
    30361 ttttcattat acggcttaaa aaaagtaaca gttgatgatt tagcagctgc tgtaaacata
    30421 tcaaaaggtt cattctatgc tttttatccc agtaaagaac atctatatgt ggaaatcaat
    30481 tttcgcttac aaaaagagtt atttacaagt atagaaacaa ctgttaaaaa gaaaaagtat
    30541 aagaaccata gagatttagc aaaggacgtt attatgctaa gtttaacggg ggtgattact
    30601 tcgcctattc tttcacagat tgatttatct ttaatggact atctgcaaag aaaaatatcg
    30661 tcagatattt ttgaaaatca tatgtacagt gatattcgta tattggagat actggaaggt
    30721 ttaggggttg tatttttggt tccgcatacg gttatcataa aatccctgta ttctgtttta
    30781 tcctgtttgg aacaattcaa agaggacgaa gaattgaata tggtacaaaa tcttttagtg
    30841 aatggtatta ttcagcaagt agtagcagag taataatttt gtttggttat ttgacaggca
    30901 agtggccaaa caaatttttt acagtttata tgactatata tctataaacg tcataaagtt
    30961 aaaggaggaa agaataatga ttgatgtaaa aaaactgtat tttagttata ctgacaaacc
    31021 gtttgttgag aatgtaagtt tccatgttgg gagaggagaa attttcggtt ttttaggacc
    31081 ctctggtgct ggaaaatcaa ctattcaaaa aattttaact gggcttaata caagttataa
    31141 aggcagcgta aaagttgcag gtacagaaat aagggagcat acaaaccggt tttatgaaaa
    31201 tattggagta gactttgaat tttcaacctg ctacgagaaa ttcacagcac gacaaaatct
    31261 cgcctatttt gcttctctat atgacaagca acctcggtct attgatgaat tattgcatat
    31321 ggtaggctta gaaaatgatg gggacaaaaa agttgctgac ttttccaaag gtatgcgttc
    31381 tcgcttgaat ttcattaaag cgttagtaca tgaccctgat atattattcc ttgatgaacc
    31441 tacaagcggt cttgacccta caaataatcg tttaatgaaa gatattattc ttgcggaaaa
    31501 gaaacgcgga aaaacgatta tcattactac tcacaatatg tatgacgcaa cagagctatg
    31561 tgaccaagta gcctttattg ttgccggaaa agtcagtgca ttggatagtc cacataattt
    31621 gattatgtca aggggagctg ccaaaataca ctatacctac tatgataaag gcgagaaaac
    31681 cggagaatgt ctgcttgata gaaccacaga agataagttg ttaaaaagtt taatttccga
    31741 aaaccgtctg ctttctattc atagtagtga gcctacatta aatgatattt ttgttgatat
    31801 tacagggagg acacttcaat gagattggga cgtttaattt gtggtgatat acatttccaa
    31861 tggaaatatg gtttctattt tatctacttt atattaacag ttttatatgt gtgtgggatt
    31921 gccgctttga cgggacattg gaaaacggat attgcttcta tcatgatata ctctgacccg
    31981 gcagctatgg gattgttttt tatgggggcg attgtccttt tagaaaaaag ccaaaaggta
    32041 ttaaatgcta tggtagtatc gcctgtaaaa gtatcggagt atatactttc aaaaaccatc
    32101 gcattgattg ctatttctac aatcattgcg gtgatattgg gatttgtttc cggcagcaat
    32161 catttacttg gtatcgcagt tggtacagct ttgacatcag caatctttac tatgcttggc
    32221 attatcgcgg ctacaaaaat ttcaaacttg aaccaatttc tcattgtgat tatgccgata
    32281 gaaattgttt gctttgttcc acctatcgtt ggtctgtttg taaagttacc agatatattc
    32341 cgcttttttc cgttcacagc ttgcatgaac ctcataactg gaaaaagcat tttactatcg
    32401 tttgatatgg tacttgtaat tgctacgttg attatcctct acatagttgc gcgacataca
    32461 gttaagcata tgtggagaag tttgggaggt gtaaagctat gaaaaggata ttatccagta
    32521 ccatacaggt atttaagcaa atcaagagcg accctatgat gtttgcagct tgttttacgc
    32581 cttttgtcat gggagctttg attaaattcg gtattccctt tcttgatgga ataacagatt
    32641 tttctttgca aacatactat ccgatctttg atttattact ttctatcatg gctcctgtat
    32701 tgctctgctt tgcatttgca atgattacat tagaggaaat cgacgataaa gtgtcacggt
    32761 acttttcgat tacccctctt ggtaagtcgg ggtatctctt tacaaggttg ggagtaccct
    32821 caattatttc ggcggtcatc gcttttattg tactgttgct tttttcatta gaaaagttgt
    32881 ccattggaat gacaatatgt ttggcgcttc tcggctcagt acaggcaatt attgtttcgc
    32941 ttatgattat aacattatca agcaataaat tagagggtat ggcagttaca aaactagctg
    33001 cacttacatt actcggaata ccagctccct tttttattga tagttactac cagttcgcgg
    33061 ttggcttcct tccatcattt tgggtagcga aagccatgca gaatgaagcg gttctttatt
    33121 tctccatagg attgatggta gctttggtct ggtactactt ccttataaaa cgtctgttta
    33181 ggaagctggc aggataagaa ggcatattat ggaaaaaggt agacttctgc aaaacgaaaa
    33241 tataaataag gctattcagg tttccaaaat cacactaatc atcaacctgg gtttatcgct
    33301 acttaaattt gctgccggat atataggaaa gtcaagtgcc atgctgtcgg acgctgtaca
    33361 ctcggcttct gatgtattaa gcacaatcgt tgtgatggtt ggaattaaaa tatcagaaaa
    33421 acagcctgat aaagaacatc cttatgggca tgaacgtatg gaatgtgtgg cttccattat
    33481 tctctctgtt gcattggcta taacgggtgc tggaatagga tattcaggta tcaagaaaat
    33541 cttttcagga cagtacaata cgctttctgt ctctagtgga atcgcactta cggcggcagt
    33601 cttatccatt gttataaaag agtggatgta ctggtataca agaagtgctg caaagcatac
    33661 aaattctgac gcacttatgg ctgacgcatg gcatcaccgc tctgatgcac tctcgtcggt
    33721 tggttcctta attggcattt taggagcacg tttaggctat gctattctcg accctattgc
    33781 aagcattgtg atttgcggtt gtatcttaaa agctgctttg gacattttca aagaaagcat
    33841 taacaaaatg gtagaccata gttgtgacaa tgctactgaa acgaagatta gggaagttgt
    33901 gcttcagcag caaggggttg atggtattga tgaattaaaa acccgcatgt ttggagcgaa
    33961 aatgtatgta gatattgaaa tattagctga tggtaattta gctctttatg acgctcatag
    34021 aattgctgag ggagtccatc aaacgattga aaacaacttt ccacaatgta aacattgtat
    34081 ggtacatgtt aatacgaatg aacttcccta ttctccatag gacagggaag atgatttaag
    34141 actattgaaa gggaaaggag gggaagtagg ttatggaaca atactggtgg attatcattg
    34201 ttatggtttt gattgtcgtt ggcttactta aaattgtaat tatgaagaag tataaccaaa
    34261 ggagaaattc taacaatcgt tcaaaaaata gcgaggatga caagatgtat taagagcaat
    34321 tatccgatgg tatgagatat atacctatga aatttgaacg ataaatccca gtttgtaaaa
    34381 gtcaataaat ccaaagataa atttgtattt gaaaggagtt ttgaagaatg aaaaaatatg
    34441 agtatgtaga aattaattat aatgcgaaag gagttgtatt cctttgtact gataaacaca
    34501 aagaaattat tgacagttat gcaaaaacgg ggtatcacta cgcagggttt gtacccacag
    34561 aaattgacgc aaaaggctgt atgcgaaaga tagatttaat ttttgaaaaa gaagattaac
    34621 ttattttagg gagttggttc taatgatagg acttaaaaga cgagatatga attatattat
    34681 gaaagttggt gctaaagctc aaggtgtttc tgtatctgaa tttagggcta tgctacaaga
    34741 taccatagac aaaactatgg aaagtacaga cccagacgtg caggcaaatt ttaaacgata
    34801 ctttggaaat aagcggccaa caccagagga atatatttat acgattacca aaaagacaaa
    34861 ggttaaggtt taaatgttgt aaagggggct tgccgtatga aacgctttaa atacaattca
    34921 gtatattcaa gcccaattta acagcatact atttacaatt aaatacgcta taccagtagc
    34981 tcgtacaaaa tttatatttt gtgcgggctt ttttaatacc cgaaaagttt tttaattatt
    35041 ttcatttttt tggaagcaaa tcacaccttg ctgtacagat atggtgcgga aagagggata
    35101 aacacttttc aattcatagc tggaaaggag gtgagattat gaaaccgtct gacttccaaa
    35161 aaacaattca gtgtcagttt gaatgtaagc tgaaaaaagt tgtcaaaggt attatctgga
    35221 actaccgcaa agaattaaga cgaagaaaaa acaaggaaat atcttttagc gaattaccag
    35281 acattacggt agaaagtctg gcaacatggg acgactacga aacaaactac acaattttta
    35341 atgtgtgtgg catagatatt aaagtccttg atgatgaact tgcagaagct ctcaaacagc
    35401 tacccgaaaa aaacgtaaca atgtattgat gtattacttc ttggaaatga gtgatacaga
    35461 gattgcagat attatgaatt ataccagaga ggctgtgttc aaacacagac accgtgcact
    35521 agaaactatg aaagagatac taaatgaaaa gacaagacag taaaggacgc aatttgcgtc
    35581 ttggagagag ccagagaaaa gacggaagat acgtttataa atataccgat atattcggga
    35641 agccacagtt tgtatattct tggaagcttg tacccacaga caagacacct gctggaaaac
    35701 gtgatgatat atcgttgagg gaaaaagaaa agcagataaa aaaagacctt gacgacggta
    35761 tcgacacggt gggcggtaaa atgacagtct gccagcttta cgaaaaaaag aacaatcaaa
    35821 gaaagaacat caagagaaac acggaattag gacgacagta tcttgtgaac gcactggaaa
    35881 atgacccatt gggtatgagg gcgattgata cggtcaagca gtccgacgct aaagaatggg
    35941 ctatcagaat gaatggcaaa ggttattctt acaagacgat agataactat aagcgttccc
    36001 taaaggcttc attctatatg gcgatacaag acgactgtat cagaaaaaat ccttttaatt
    36061 ccaagttgag tgatgttctg gaagatgata cggaagcaaa ggttatcctg acaccagagc
    36121 aggaagaaaa actccttgcc tttatggaaa cagataatgt ttacagcaag tatcgtgatg
    36181 aagttattct tctgctggaa acgggacttc gtatctctga attatgcgga ctgacaacac
    36241 acattgatat gcttaaccgt gtgattaaca tagaccacca gctattgcgt gatacagagg
    36301 tgggctacta tatttccaaa gctaagacaa aaaacggtaa gcgagagctt ccattaacag
    36361 aaagagcata tcaagcactc aagcgaattt taaagaaccg aggaaaagca caaccgcttg
    36421 ttgttggtgg ttatagcaat ttcttattct tgaaccgtga gggattgcca aaggtagcag
    36481 gaaattatga aagtatggtg cgtgggttga ttaagaagta caacaagacc cataaggaca
    36541 agttaccaaa catcacgccc cattcattca gacatactta ctgtacgaac atggcaaata
    36601 agggaatgaa cccaaacacc ctgcaataca tcatgggaca cgcaaacata accatgacat
    36661 tagggtatta tgctcacggt actttccagt ctgcaaaggc agagttagaa aggctggctt
    36721 cttaatatcg aaaatgtatc ttactactta tttactactt ttggttgcat tttcatgctg
    36781 gtaaatgcca gcttatgcaa ggtatcttcc aaaaagaaaa tgcccataca gcccgaaaat
    36841 gcgggatata tcggcatcta ccaacttatg aaaagataat cagaaattta gtaagttttt
    36901 ataataaaaa aataagaggc tgtccaaaaa tagagataag ccttttttca taatcggaat
    36961 tataaaaata cacttgattt catatgaaaa agagtgtctc ataaactaaa aagtttactt
    37021 tgagacacta ccttttttat tcttatttat actttgtaga catattataa tatgcgtttc
    37081 actggtatct gaacttctgt caaccagtct tcttcactct ctttattcca tataccatct
    37141 atataagatt ctctaggatt tccaaccact ttatatttat tgtcctctat ccatttaaat
    37201 gcatctgcat aagtttttcc taatgttgaa tatggaccat tgtgtaatat acaaactgca
    37261 ttttcaactg catctaattc tttaaatttt aatatatccg tatcttcctt taaatcattt
    37321 atagcttgac acatttcaac atccatatca gtctctctat attcaccatc atgatatata
    37381 ttaaaacaat aatcaggaac tgcacatgta caccctgttt tcatcatttc ttcagccatt
    37441 acatttggaa atagattaaa aagttcatca tatcccttta acacttttct catagaagca
    37501 actttaactt ttggtaaaga cttaataatt acatcattca tattgacttc tcctttcaaa
    37561 ttcataaggt aattacgtag tttaattatt ttatattctt cacttttaat tacatccaac
    37621 atttcttttt ctttattcat taaaatattt tcaacttctt caggattttc tacagctttt
    37681 tttatctcag ctaatgataa acccatttgt tttaaagtta ttatctgatg taatttaggt
    37741 aattgctctg ttgtataata cctatatttt gtaaattcat ctacatattc tggttttaac
    37801 aaccctatat cttcataata ccttaatgtc tttgtagtta ttttatttat tttagaaaac
    37861 attcctatag aaaacatctc atcacctgcg cattagattt gattaattta agtttaaact
    37921 ttccccttag gttaaagtca atacaaaata aattataatt gtattaattc ttcaattcta
    37981 tctccactca ataccaaaat atcccctgtt tttataatgg ttgaaccttt aggtattaaa
    38041 acctgttcct ttctttttat cataactatt aatatatcgt ctggtatatt agaatctatt
    38101 atactcttat tagcccattt attaccctca tcaacattta cttcgataag tttagagcta
    38161 atttccccat cataatcatt aaatgttttt aatacaggtg tattatcatc aactaaatcc
    38221 aactttctgg ctacagttgg tatcaatgaa ccttgtattc ctactgaaag caacgctata
    38281 aaaaatatta tatggaatat gtcattctct atggctactc cttgagtaac agcataaatt
    38341 gcaaaaacta ctgaagccgc acctctaaga cctacccacg atatgaataa tttttcttta
    38401 tttgagaatt taaattttgc tagaactata aatgttgcta atggtcttgc aataactatc
    38461 atgaatatag atatggccat tgctatacca aatacatttg gtaacttaga agggaaagat
    38521 aacaatccta acataaagaa taacattatt tgcataatcc atgaaattcc atcaaagaaa
    38581 tgaaccaaac tttttttaag aggtatccta ctatttccta taataatacc tgaaatgtaa
    38641 acacttaaat atccatttcc tccaagatac tcgctaaatg cataagaaag tattgcaata
    38701 gctgttataa atatagtata aaatccttct atctcgaagt ttgaatgcct taaaatataa
    38761 acagataatt ttgctagtat aaatcctata gctaacccaa aagctatttg ttttattacc
    38821 attggtgcaa taagttctac cccagaatta ttcatcaatg tcaaaagaat tagtgtcaac
    38881 atatacgcta ttgggtcatt acttccactt tcaacttcta ataatgatgc aagtgaaccc
    38941 cttaagttta gtttttgtga acgcaacaca gcaaacacag atgcagcatc tgttgaagct
    39001 gcaattgccc caattaataa accttcaagt aaactagttc ctattaccat gtggcaaaac
    39061 atacctgtaa ccccagacgt aattattaca cccagtgaag acattaatat agaaggtata
    39121 gcaacaggtt tagccatatt ccagtttgtt ccaaaccctc caaaaaacat tataaatatt
    39181 agtccaatag aacataattg ttttgttaat tcatagttct gaacctccca tgactaaagt
    39241 cacagagttc ctgcttcata gaattttgca tactaaaata tgtcttacta attctccaca
    39301 ggctatcccc
//
LOCUS       DAMJWO010000034        38835 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.035, whole genome shotgun sequence.
ACCESSION   DAMJWO010000034 DAMJWO010000000
VERSION     DAMJWO010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38835
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.035"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(68..679)
                     /locus_tag="PC366_001777"
     CDS             complement(68..679)
                     /locus_tag="PC366_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2577307.1"
                     /translation="MKMVKKLILSTIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
     gene            complement(771..1760)
                     /locus_tag="PC366_001778"
     CDS             complement(771..1760)
                     /locus_tag="PC366_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HDF2577308.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISV
                     PSQDASMLFMPGYVEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSR
                     NRESREKFAEEMNLKLSKYNTKIVAVESSDEAIDNADVIVLATPSKQPVLNGNLVKKG
                     ALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGIDWKW"
     gene            complement(1827..2690)
                     /locus_tag="PC366_001779"
     CDS             complement(1827..2690)
                     /locus_tag="PC366_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HDF2577309.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASI
                     NLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSN
                     KIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSI
                     KVRYYTYSGGAHGFYQDIAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELE
                     KKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSML
                     KPEYVDLFDLK"
     gene            complement(2796..3392)
                     /locus_tag="PC366_001780"
     CDS             complement(2796..3392)
                     /locus_tag="PC366_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheB"
                     /protein_id="HDF2577310.1"
                     /translation="MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAI
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGANGLLKMKENGLFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            complement(3432..4235)
                     /locus_tag="PC366_001781"
     CDS             complement(3432..4235)
                     /locus_tag="PC366_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HDF2577311.1"
                     /translation="MIKLTDEEFIVLVNHVKKEYGIDLSKKRALIEGRLYNTMIEKKL
                     SSFSQYMNLLFKDKTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKSFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR"
     gene            complement(4271..4711)
                     /locus_tag="PC366_001782"
     CDS             complement(4271..4711)
                     /locus_tag="PC366_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HDF2577312.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVIHI
                     ENLNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSI"
     gene            complement(4724..6826)
                     /locus_tag="PC366_001783"
     CDS             complement(4724..6826)
                     /locus_tag="PC366_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HDF2577313.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESTDEKEAIDSNFEYKED
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQ
                     FVAKEDKAIVYKTIEDNLYVKEYINISKKEIEMKNTSNNDAVENKLKDNNKVSKSYQN
                     NYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKNVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVG
                     KIVLSAENLGGEAVISISDDGRGIMRDKILAKAKEQGLLKHQINEYTDDEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMHGNMIIIENEHKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            complement(7083..8786)
                     /locus_tag="PC366_001784"
     CDS             complement(7083..8786)
                     /locus_tag="PC366_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HDF2577314.1"
                     /translation="MKREVKLSKLAIVLLIIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQSIIFGSDYINSQEKMDSLI
                     NEFQEDIVTRSNSKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINRV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVGFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVRIAKETANALDLVVNGVEKTTNYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKESEVRESSW
                     V"
     gene            complement(8812..9771)
                     /locus_tag="PC366_001785"
     CDS             complement(8812..9771)
                     /locus_tag="PC366_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2577315.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKTLTKDNFKVKKAFNAIEAKE
                     FIEEFIPDIILLDIILPDNSGFEFCKEVKSNTRTADIPIIFITSKNTDTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTVISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEGAKILSERIRKEIKEFDFNYKEHKIKCTITLG
                     VVEVNSNISLEENISLADKAMYEGKNLGKDCSVVSTMKGLKKI"
     gene            complement(9907..10425)
                     /locus_tag="PC366_001786"
     CDS             complement(9907..10425)
                     /locus_tag="PC366_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-binding chemotaxis protein CheW"
                     /protein_id="HDF2577316.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFKVDEQDFGVELEKVIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMRLRLKKDELMTTNCMYIVVTEIKDLVVGFV
                     VDRVDDIVSLEKSKISPPPRVTIEYSDYFVSGVGELEGKIITLLDLEKLLTDKDEVLI
                     DELINGFDCTIM"
     gene            complement(10468..10953)
                     /locus_tag="PC366_001787"
     CDS             complement(10468..10953)
                     /locus_tag="PC366_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HDF2577317.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKCKFADTGINELIKSMENIGANRIYIKAKIAGGAQMFLGSSN
                     SVIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELLVDSINKGKKK
                     L"
     gene            complement(10950..11567)
                     /locus_tag="PC366_001788"
     CDS             complement(10950..11567)
                     /locus_tag="PC366_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HDF2577318.1"
                     /translation="MINYLELDDVHIDALREIGNIGSGNAITALASMINSNVEVLIPM
                     VKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLMLSSLFNKEEAF
                     LDEIEAIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVGAVLNVPMIRF
                     SDVGDKVLFIENKFKMSDNYFTSHILMIPEMSSLREILVRLGLEV"
     gene            complement(11633..11995)
                     /locus_tag="PC366_001789"
     CDS             complement(11633..11995)
                     /locus_tag="PC366_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDF2577319.1"
                     /translation="MENKILIVDDAIFMRMIIKEALSKSGYNNLIEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVEAIKLGALDFI
                     VKPFKTETLVKVVNNVLK"
     gene            complement(12739..13236)
                     /locus_tag="PC366_001790"
     CDS             complement(12739..13236)
                     /locus_tag="PC366_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HDF2577320.1"
                     /translation="MNYEIVEINEKIVIGISKETTNKDGQAVNAIGELWKKFMGKGIY
                     NAIKGKKNDKTIGLYTDYQGDFTSPYSFVACCEVNSNSDKEKNLEELNTNNTVGESII
                     SKVILAGKYAKFVIVGGQKEVGDFWFKFWQMDFDRTYISDFEEYQCNTFDTKKQEIHI
                     YIGIK"
     gene            complement(13411..14322)
                     /locus_tag="PC366_001791"
     CDS             complement(13411..14322)
                     /locus_tag="PC366_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HDF2577321.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMTKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNTINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKDEVFSRKIIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDDTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLRELSKIYSL"
     gene            15247..16098
                     /locus_tag="PC366_001792"
     CDS             15247..16098
                     /locus_tag="PC366_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HDF2577322.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVVGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKKTKEI
                     KSTEGEC"
     gene            16102..16572
                     /locus_tag="PC366_001793"
     CDS             16102..16572
                     /locus_tag="PC366_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577323.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            16585..17895
                     /locus_tag="PC366_001794"
     CDS             16585..17895
                     /locus_tag="PC366_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2577324.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYKNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKKGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHASDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVEITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIIPAK
                     AMALTVVDLLFDNAKDAKDILDTFTPVMTKEEYLTFLEKHDKTL"
     gene            18107..18853
                     /locus_tag="PC366_001795"
     CDS             18107..18853
                     /locus_tag="PC366_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2577325.1"
                     /translation="MFNAGNRIINTWLYPIQDGFVLIDTGYENGFKHFKKRISKFNIK
                     IKDIRYIFLTHAHDDHVGFLNQILDESPNTKIVMHDKALEILYKGQNSFIGGCNSRTA
                     FLFCQIMKLFGKGEHSFSPLKQEFEKRCILVSDKNRKEIEKELNGKIIDTPGHTADSI
                     SLLIDDGVLFCGDSAMNGFPSTHKITIFAESKLEFIQSWKTIINTKPKMIYPGHGKPF
                     EYSKLEQNLIYVNKINLYPLHNSKDIHRFL"
     gene            19215..20756
                     /locus_tag="PC366_001796"
     CDS             19215..20756
                     /locus_tag="PC366_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HDF2577326.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SLVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAELDVDGSLSDVEKKGLKKAGISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMVFNIPLGPGIL
                     PSYSM"
     gene            20791..21897
                     /locus_tag="PC366_001797"
     CDS             20791..21897
                     /locus_tag="PC366_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDF2577327.1"
                     /translation="MLDKNRLINNFMDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGEKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPILDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVTTEKIPHRDIYLCFTICEEAGMHGVKNFNPDNLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFHGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DPLTTSNIGKIEGGGATNIVTDKVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHSMSYPSFELSRDSHVFKLSEEAIRQVGVVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(22483..23769)
                     /locus_tag="PC366_001798"
     CDS             complement(22483..23769)
                     /locus_tag="PC366_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2577328.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDSDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFNLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRHSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAISENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(23892..26990)
                     /locus_tag="PC366_001799"
     CDS             complement(23892..26990)
                     /locus_tag="PC366_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF2577329.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKAMGINDISHVK
                     CYKALQGKDSPCEFCTNSILKEDEYYIWENTNTRTNRHFILKDKLIKWEGKHARLEIA
                     LDITEKEDISKSIAEKLEIKELLVGCIKHLITESNFSDAVNLVLTNIGKFHKADRAYV
                     FEVSEDRKKVTNTYEWCNEGVDEQKQALTNLDINELKNWFLLFEQKGFVIIDDIENIK
                     EEQPIEYEILKPQKIESLMTSSLKQDDKVVGFIGVDNPHKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTGAYNRNKYIKYIDNFQKGKFKSIGVVFVDINGLKDIND
                     NFGHANGDSAIVSACVIIKKYFHSYNVYRIGGDEFIVLCEDISKQLFEELVSWLSEEF
                     KDEMIYSVAVGSIWSDDNIDIHKLIKVADERMYQDKKRYYNKNKLRNNEMEVISDLAD
                     STNNILFKHKELVDKVYFDDLMIKGYSKAYEKLAYNTYDIILSICIDTNLITPIYQSE
                     SNIFSFPIKENLEKTFSYIKKHLIHPDDIILFDDNHLLKSLDSLNNSKQDDLELNFEY
                     RRLGIDKKYYWALIYMLKISSKNKLGEKQTHILVAIKNIDYLMQLHKNQKDILTGLYN
                     YESFCEQTSLMLKRYPDKSYAIIMMDIDKFKVINDIYGVRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDRDVHKLIYKIKNSLNRKKFEYMLVPCFGVYKILDNN
                     IPITNACEMAGYAHKKVKKQSINNYIFYDDTIRNDALEEKQMEREMEYALENGQFHVY
                     LQPKYNLNANKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIRLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYSIPKSFLELELTESLFIKN
                     IKLFTKIIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNEEGITDREK
                     IVLRHTIAMAKDLDMDVVAEGVETKEQAEFLVSLDCVVIQGYYYCKPIPSADFEKLLY
                     QK"
     gene            27714..27866
                     /locus_tag="PC366_001800"
     CDS             27714..27866
                     /locus_tag="PC366_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577330.1"
                     /translation="MKIFSFLLFVVGICFCIAGFMGHYPAFAGATLSFFATTMIAVRQ
                     VKTKKK"
     gene            complement(28158..28862)
                     /locus_tag="PC366_001801"
     CDS             complement(28158..28862)
                     /locus_tag="PC366_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2577331.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQDNINNDAPKSFEVKNLKIDYENHIVSINGEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(28853..30460)
                     /locus_tag="PC366_001802"
     CDS             complement(28853..30460)
                     /locus_tag="PC366_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HDF2577332.1"
                     /translation="MKKERLQHEDLKEYDYDEDGYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGVACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESN
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPMYDEEGKDKWK"
     gene            complement(30714..31892)
                     /locus_tag="PC366_001803"
     CDS             complement(30714..31892)
                     /locus_tag="PC366_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577333.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVGAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(32118..32612)
                     /locus_tag="PC366_001804"
     CDS             complement(32118..32612)
                     /locus_tag="PC366_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF2577334.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNMGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTKIKENEKYKKSINKI
                     KQQK"
     gene            complement(32613..33374)
                     /locus_tag="PC366_001805"
     CDS             complement(32613..33374)
                     /locus_tag="PC366_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDF2577335.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFVGVSIAVGMFLVLGLYFKLGGI"
     gene            34097..36931
                     /locus_tag="PC366_001806"
     CDS             34097..36931
                     /locus_tag="PC366_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2577336.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKTGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKISGKPILFLHVSIIENLIGRTLNSDEFSINNCNELLKSSKN
                     DSEDIFSTLLGHDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIVHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIKVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSELDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNISKIVLSIIENDLQTSLPKDEVKFISMFLN
                     SMYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     TIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDSTEINYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNIRKYNINLVPHNIESFKMYKNKFSNTKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     FTIIELIDENLKSKFKLGYILHCSFMIERCFKNTTFPYNNITELISKNHELYSLIREA
                     FKPTEAYFNILIPDEEIAYIIDMINEYLNK"
     gene            36974..38218
                     /locus_tag="PC366_001807"
     CDS             36974..38218
                     /locus_tag="PC366_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF2577337.1"
                     /translation="MEDEILKGKIKQLTILALIFIFITPVFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAVDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAAIAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENMSTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMVPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSATLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKITVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVAKYYNDSGKFVGSVDVKSESNIGCIPLKDK
                     IKIKVAKINKKLEIKNSVCFKV"
     gene            complement(38659..>38835)
                     /locus_tag="PC366_001808"
     CDS             complement(38659..>38835)
                     /locus_tag="PC366_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HDF2577338.1"
                     /translation="TYKTAIDEAQAILDKADATQKEIDDAVTALNTATATFEAGKVPT
                     TIALMLSRILGFMK"
BASE COUNT        13023 a         6466 c         4510 g        14836 t
ORIGIN      
        1 taaaataaac tatcttccaa acattttatt atatgcttaa aagatagttt tgtgtcttta
       61 aaataaatta aattgtatat attccttcac ataacttttg tatattacta ggtggttgcc
      121 atttaccatc ttttttagta tatgtaatca tagttgtaac ttccttagtt ggtttcttat
      181 tgtaaaggtc tataatcatt tttgtcatat catcttgaac ttctttttct tttttatcgt
      241 aattcttttc atcagttaca taagatttta ctaaagtgtt cgcttcactc attactttac
      301 tagtatctaa agctttactt acaactttca aagttatctt atccttacta gaagattcca
      361 ctgttactgt cttttcaaca ccttgaatta atttaacaat tgtttcgtat atcttttcag
      421 cattttcttt accataaaga ggtgtcaatt gagcaatcat tgaaaccttg tccttgctgt
      481 tataagtttg aatctgttta tattcagctt ctgttaatgc atcagaaatt cctttttcat
      541 catacttata catttctaat gcagctaaat tagcttcaaa attcgacttt actttttctt
      601 ctgcattaga acaccctata gttagaacta aaactagagc cataatcgta gacaatatta
      661 acttttttac cattttcata caaacatcct ccctcaatta aaataataaa aaatttattt
      721 atcaacatta taacataaat ttgtctaact atagaattat tttgaatatt ttaccacttc
      781 cagtctattc caataccgtt ttcttttgct ttatcgtata ttctttttgc tgttacgaca
      841 tcttgtacac ctatcccaac agttttaaat acaattatct catcatcatc ttctcttcca
      901 ggaatagttc catttataac gtttcctaaa tcaccactaa aatcatcttt acttatctta
      961 ccttctttta atggaattaa tatatctcct gactcagata aaactgcatc tgttgattca
     1021 aaaaatatct tagacgctct agttaaacag tttgggcaca actcttgcat atctggcata
     1081 tatgaaccta ctgcacttat taaagctcct tttttcacta agtttccatt aagtactggt
     1141 tgttttgatg gagtagctaa aactatcaca tctgcgttat ctatggcttc atcagatgat
     1201 tcaactgcaa ctattttagt attatattta cttaatttta agttcatttc ttctgcaaat
     1261 ttttctctac tttccctgtt tctactaaaa actcttacct catccaaatt tctagcttct
     1321 atcatggctt caagttgtgg ctcaccttgt cctcctagac ctatcaaagc tccaatctta
     1381 gaatcttttt tagccaatac atctatagct gctccagagg ctgctccagt acgaatctga
     1441 gttacataag taccatccaa tactgcacta acttctccag tttctccatc taataatagt
     1501 actgttgctg gaattactgg tttgcctttt tgagcatttt taggaaatac agatacaatt
     1561 tttattcccc cacagcctaa ttcttctacg tatcctggca taaataacat actagcatct
     1621 tgacttggaa cagatatatt ggttctcaaa ggatttacac tctttccttc acaataaatt
     1681 ctaaaagctt ccttatcagc ttcaattgca tctctcattg taaatacttt ttttatgtcg
     1741 tcttttttta aaagtagcat ttttataccc ccaattttaa taagtttcta tgctaaatat
     1801 tatagcataa catttaattt aatcttctat ttcaaatcaa ataaatctac atactctggt
     1861 tttagcatag aacttatcaa cgctttattt attgaaaatt ctggtattcc cgctgcatat
     1921 ggagttatat catataaatc aaaatataca actagattct catcttgcaa gtaaaagttt
     1981 tgattctctt ttataccttt aaaattatat attccgatat tttcttcatc ctttttttca
     2041 agttcagcta tttgtctttt aatttcttca tctataactt ctttatattt agtattatcc
     2101 ttaaataagt ccattaattc taaaaatttt ccagttctca tatccacatt atatgctata
     2161 tcttgataaa atccatgtgc tccaccacta taagtataat atctcacttt tatactaaga
     2221 gcagaatcag tattcttttt aagttcaaag tctacatttg caacaaactt atttttctcg
     2281 tcaggattat ccttaagata ctgctttgct tctttatatg atttattata aaattcaaat
     2341 atgtcatttt ttatcttatc atttgtagac ctttcaacaa ttttatttga atttgttatt
     2401 acaggcatgt ttatagtact ttctaaatac tcatcatttt tcactattgt tttacttcct
     2461 attgtactta ctgataaagt ttgtttacta tttgtattac cctttggtaa tgactggtta
     2521 ctcataacag tcactgcttc cttattacta tttaaattaa ttgaagcatc tttccttaaa
     2581 ttattatatt tatagtcatg tttaattgcc aaaacagcca ttatagtcaa tgttaaaaca
     2641 aatacatatc ttaaaacttt agcttttgta tcgactttaa aaaatttcat attatcattt
     2701 tcctcctaaa tataaatctc tcttattata tttggagttt ctagggtttt ttatccatat
     2761 aatttaataa aagattaatt tttatttata aaaaattaat ctttttgttt taaaatatta
     2821 atatgtctta tcaaacagtt tgaaatttca ccaagaggta attgtaacat aacagaacct
     2881 ctatcaaaag ctaccattgg cattccatat actatacaag aattttcatc ctgtccaatt
     2941 gtaaataaac cattttcttt catttttaaa agtccatttg ctccatcata acccatacct
     3001 gtaagtatta ttcctattga atttttacct gctacttctg ctactgaatc aaacaaaacg
     3061 tctactgatg gacagtgacc acttattctt tctccttttt cacaagttac ataatatcct
     3121 tgtttatccg tacacaattt catctggtaa cccccaggtg caattaacac atttccttgt
     3181 tcgactctat cattattctt agcttctctt acattcataa tacactgctt gtcaagccgt
     3241 tgtgcataca tataagtaaa tatagctggc atatgttgaa ctacaacaat ccctggtgtt
     3301 gattttggta ggtcttttat aatttcaagt attgcttctg taccacctac agatgcgcct
     3361 atagcaataa ccatattatt aaaacgttcc acattaccgc ctccaaaaaa tcatatatca
     3421 aaaatacctt tttatcgttt atatatagca ggttttacat atttgtattt agtactactt
     3481 ctgttgatta cttctgcatg tcctacaaac aaaaaactat cttttttggt agcattataa
     3541 aatttattta taagttcttc tcttgttttt aaatcaaaat aaatcataac atttctacaa
     3601 aaaatcaaat caaaatgttg atatgagaaa tcattcatta aattaaatga cttaaaaatt
     3661 acactttttc taatcttatc acaaatttta aatgtaccat ccttgttgtc tataaaatac
     3721 ttcttcttcc ataactcagg aacattgtta acatttgatt ctatgtatat acctctttta
     3781 gctttttcaa gtgagttagt tgaaatatct gtggctatga ttttaatgtt ccacaactct
     3841 ttattatatc caaaataatc atccaaagtc atagctattg aatacgcttc ttctccacta
     3901 gaacatcctg cactccatat atttatgttt cttattttat tattttcttc ccaaaaagga
     3961 agtatactat tctgtataaa ctcaaaatgt tgaggttctc tcataaaaaa tgtgtggtta
     4021 gtactcaatc tatttattag gtttatagct tcatttcctg tcttatcttt aaataataga
     4081 ttcatatatt gactaaaaga actaagtttt ttctctatca ttgtattgta taagcgacct
     4141 tcaattaacg ctcttttttt acttaaatca ataccatatt ctttttttac atggtttaca
     4201 agaactataa attcttcatc tgtgagtttt atcatgcaaa aacttcctcc tgctaattta
     4261 tcagaactaa ctatatgcta ttaatcaaaa actttcgaat atctaaaatt aatatagaat
     4321 tatcttcaac tttcgcaatc tcttttatat ctttattaat attagtgttg ttagaattag
     4381 tcgtctctag taaatttaga ttttctatat gaataacatc aacaacttta tctacaataa
     4441 ttccaacttg atactcatca acctttgtaa ttattataca agttctctca ttataatcag
     4501 ctttaggaag attgtacttt atatgcatat taataactgg tattattctt cctctcaaat
     4561 taataactcc acttatatat gttggaagac atggtacata cgttattgat tgaaatctta
     4621 tggtttcaat cacattttct aattctattc cataaataac atcatttaca taaaatgtta
     4681 atacttgttt aataatttca tctttagcca tactttaaat cccctaatat atttctataa
     4741 tgctatctgc atctataatt aaacttatac ttccatcccc aagtattgta catcccgata
     4801 aacccttatt ttttatatta aatcggttga aataaactgg aaatggtttc acaacaactt
     4861 gctgattacc tattatttca tcaacaaaaa tgcatactgc tttatgctca ttttcaataa
     4921 ttatcatatt accatgcatc agattggtta cttttgtttg aatattatat attttatgta
     4981 accttataat gggaatacat gctccatata ttgtaattaa ctctgtctta tttccttctg
     5041 taattatttg atttaagtct gtaagtttaa atgttcttct tatggatgat attggtaaag
     5101 taaatagtga atctccaact ttaaacttca taccctctac tatagaaaga gttaatggta
     5161 tttttatagt aaaggttgtc ccttcatcct gtttactttt tacttcaatt gaacctccaa
     5221 ctttttcaat acttttacga acaatgtcca tgcctactcc tcttccagaa aattcagtta
     5281 tagattcttt tgtagaaaaa cctggagtca taatcaaaga attgacctcg tcatcagtat
     5341 actcattaat ttgatgttta agaagacctt gttccttagc ttttgccaaa atcttatctc
     5401 tcataatgcc tctaccatca tctgaaatac ttatcacagc ttctccgcct agattctcag
     5461 cagataaaac tatctttccc acttcttctt tacctttcgc tatacgctcc tcaataggct
     5521 ctattgcatg gtccatagca tttcttataa ggtgcataaa aggttctgct aaattatcaa
     5581 ttacattctt atctacctct gtctctgctc ctatagttat taactctaca tttttatcta
     5641 attttttatt catatctcgt acaattctat gcattttttg aaatacacca gcaatttgaa
     5701 tcatacgcat agacattact atatcttgca attcatctgt aagcttgtgt aattgtcttg
     5761 ttgccttatt gaaattatct atatcaacac ctgtagaatt tacgctattt acaaccattg
     5821 attccataat tacaatttct ccaactatat tttgaagtaa atccaatttt tctaaattta
     5881 cactcataat actctgctta cttattggta aatgttcatt ttcttcactt agactatctt
     5941 tttccatatc agttttttca tttaaaacat cttcttgtat ctcatcttct gtatagttat
     6001 tttgataact tttacttact ttattattat cttttaattt attttctact gcatcattat
     6061 ttgatgtatt tttcatttct atttcttttt tactaatatt tatgtattct tttacataga
     6121 gattatcttc tatagtttta taaactattg ccttatcctc tttagctaca aattgtatat
     6181 aaaacccata acttttaata tattctgtag actctgcatt tgtttctaca tcttttggat
     6241 aaaaatctat aaattcacag taatctctaa gttcaaatac aagcatgaac gctctcacat
     6301 tttccatcat gcaaccttgt tcaaagatta tttttactac atcagagtct tctttgtatt
     6361 caaaatttga atcgattgct tctttttcgt ctgtactttc taaatttgca ttatcctttg
     6421 atttcataga acttgataat tccaaagtac tcacatactc ttcaattcct tcaataaaat
     6481 tagagtaatc agaagatata caacctcttg attgtagctc atctatatct cttcttataa
     6541 aatctaatga ttgaaagact aaatcaaata ataggtcatt gtctaaaact tctattttac
     6601 cttcacgtat agcataaaac aagtcttcta cactatgtgc taaagcagat atattgtcta
     6661 accccatcat agatgctgaa ccttttatcg tatgcattat tctaaaagtt tcattaatgt
     6721 tgttatgagt aaatactttc tctttttcta tttgaatcat aatttcatct aattgttcga
     6781 gtaataaact tgtctcaaat ataaacatat ctaacatttg tctcatactc ggttcaatat
     6841 aattcacatt tatcacctac gacctacaaa taattttcta ttatatatgc atctcataat
     6901 ttaaatcctt gatgattctc ttatctcact atatgtacct cataatttaa atacacaatc
     6961 attctcttat ttcaatatat atacatctca taatttaaat acatgataat tctcttactt
     7021 caatattcac ctcataattt aaatacatga taattctctt acttcaatat tcacctcata
     7081 atttaaaccc atgatgattc tcttacttca ctttccttta gatgaaattt ttctactaat
     7141 tcttttaaaa tttgagcttg agcagacatc tcttctgagg ctgctgcact ttcctctgct
     7201 gttgctgagt tcatttggac tactatggaa atttgctcta ttccagataa aatctgtgta
     7261 attgctactt cttgactatg tacagccgaa gaaataccat taatataatt agtagttttt
     7321 tctacaccat ttactaccaa gtccaatgca tttgcagtct ctttagcaat tctgacacca
     7381 ttttctactg ttttaatagc ttcttctatg agaatagctg tattttgagc tgcttttgca
     7441 cttttaccag ccaaagacct aacttcatct gctacaactg caaatcctct accatattga
     7501 cctgctcttg ctgcttcaac agctgcattt aatgcgagaa tattagtttg gaatgctatc
     7561 tcatctattg ttttgattat ttttgatatt tcactcgatt tttcacttat ttcacccatt
     7621 gatgtcatca tatcatccat acatctactt ccaaaaccaa cttgtgatgc agattggtca
     7681 gatacctcac atgcaagact agcactatct gcacacttct taattccatc tgatatctca
     7741 ttaatcgtgg aagctaattc ttctactgaa ctagcttgtt cagtagcacc ctgtgaaaga
     7801 gcttgtgcac ctgctgcaac ttgttctgaa gcacttgcaa cttgttctgc tgataaattt
     7861 atttcagaaa aatcaccatt aaaagagttt attatacttt ctaaagatat tttaattgat
     7921 ttaaaatcac ctataaattc ttggtctatc tctactctta aatctccttt tgcaatacta
     7981 gttaatgtac tgtctataag gtctatgtaa tttaaaagca tactttgcat ctttttgaca
     8041 gaactcacta atagtcctat ttcagattta ctttcttcaa cgtctatact tgttcttaag
     8101 tccccagatg caattcttga aaagtgtttt tctactctat taataggaat cactatcttt
     8161 aattttatta ctgtatattc tattattgtc aatattatta aaagggaaag tataaatatt
     8221 gttcttaata ttagactttg taattctttt tttacttcta caattttgga atttgaacgg
     8281 gtaactatat cctcttgaaa ttcatttatt aaagaatcca ttttctcttg ggagtttata
     8341 tagtcactac caaaaattat actttgagct ttactcttat cattactttc gactgccttt
     8401 attgcacttt gttctgttgg tactaaagaa tctgatattt cttttgcttc taagatttta
     8461 tttgactcgc tctttgtaag accaattttt tctaatttgt ttaaagctga ttctcttgtt
     8521 tttccgtata attctttttc ataaatatct ttattctttt tttctcctgt aaatacatat
     8581 cttcttaata catcacttat ctctctagtt gtatctttta tatactgact ttgagtcctc
     8641 aaattattca tatcattaat acttttttct actttttcaa atgctttata agatgaaata
     8701 gaagaaaaaa tccctgctag aacagccaat actataataa tcagcaatac aattgctaat
     8761 ttagaaagct ttacttctct tttcatatct gtactccttc ataaagtaag tttatatctt
     8821 ttttaatcct ttcattgtac tcactacgct acaatctttt cctaagtttt taccctcata
     8881 cattgcttta tctgctaagg atatgttttc ttctaatgat atatttgagt ttacttctac
     8941 tactcctaat gtaatagtgc actttatttt atgttcttta tagttgaaat caaactcctt
     9001 tatctcttta cggattcttt ctgaaagtat cttagcacct tctattggag tatttgtgag
     9061 cattatcaaa aactcttctc caccccatct tgatacagta tcaatttgtc tacaattctt
     9121 ttttattata cttgatatta ctgttaacac gaaatcccct gcttcatgcc cataagtatc
     9181 attgataacc ttaaagtcat caatatcacc aaggataagg gatattgatg tttcactata
     9241 tttattaatt cttctttgct ccataagctg attaattata tgtcgcctat tgtaaagacc
     9301 tgtaagataa tctcttacaa cgagtctatt caatttttca agagaagatt ccagttcatt
     9361 atttatcttt tttaatttat cttgagattt ctttacttca agatgagcta taacacgagc
     9421 ttttaattct gtcatactaa aaggtttcac catatagtca attgctccta caccaaatcc
     9481 ttttactatg tctgtatctg tattttttga agttataaaa attataggta tatctgctgt
     9541 acgagtatta gattttactt ccttacaaaa ctcaaaacca gagttatctg gtaaaattat
     9601 atcaagcaaa ataatgtctg gtataaattc ttcaataaat tcttttgcct ctattgcatt
     9661 aaatgctttt ttaaccttaa aattatcttt tgtaagtgtt ttatctatta agtcacacat
     9721 cagaacacta tcatcaacga ctaaaattgt tccctgttgc ttatttttca tatacaaacc
     9781 tctcttaaac ataatatatt caaattttaa tgatttaaaa tttttatact taataattat
     9841 accactatat tcttaaatgt tctcatcaca atctttttat aataacactc caactacatc
     9901 cctatgttac atgatagtgc aatcaaaccc attgattaat tcatctatta aaacttcatc
     9961 tttatctgtc aaaagtttct ctaaatctag taaagtaatt attttacctt ctaattctcc
    10021 aacgccactt acaaaataat ccgaatattc tatagtaact cttggtggag gtgatatttt
    10081 acttttttct aagcttacta tatcatcaac tctatcaacc acaaatccaa ctaccaagtc
    10141 ctttatttca gttactacta tatacatgca atttgtagtc attaattcat cttttttaag
    10201 tctcaaacgc atatctatta ttggaatgat ttttcctctt agatttatta tgcctttaga
    10261 atatgtaggt agttctggaa taaatataat ttcttgattt ccagtaattt ctattacctt
    10321 ttcaagttca accccaaaat cttgctcatc tactttaaac tttagatact taattccttc
    10381 atcaattagt ccataatcta aatatgggtc atctggaaat ctcatttaat acctccctcc
    10441 taaaatacac tttctatgaa atatatatta taatttcttc ttacctttat ttattgaatc
    10501 tacaagtaat tcacccgtct cagtgtaaaa acgtattgtt ctaccataat tcatacctgt
    10561 gtcctcagct aatattggaa tatttaatcc taaaagagtt ttttttactg cctcaacatt
    10621 cctatgtcct atacttgcaa ttactgaatt gctgcttcct aaaaacatct gagcacctcc
    10681 agcaattttt gcttttatat atattctatt tgcacctata ttctccatag atttaatgag
    10741 ctcatttatt cctgtgtcag caaatttaca cttattttca atgttaatag catctttact
    10801 atatggcaac ataacgtgta acattccacc aattccagct actttatcta tcaaacatac
    10861 tcctacacaa gagccaagtg cataagtaac taaaacattt ggtctatagg ctatcttcat
    10921 atctgcaatg ttcactacta tctctctatt catacttcta atcccaacct cacgagtatt
    10981 tctctaagtg agctcatttc tggaatcatc aaaatgtggc tagtaaaata attatcactc
    11041 attttaaatt tattttctat aaataagact ttgtcaccaa catctgaaaa tcttatcata
    11101 ggcacattta gaacagctcc aaccatatca atacatatat ctggaattga aacacttata
    11161 gtcatgttta acatagatgc aatagcattt acatatgaac ttgccataat atttcctatt
    11221 tccttaattg ctgaaatttc aattgcctca atctcatcta aaaaagcttc ttctttatta
    11281 aaaagagaac ttagcataag ttgagttatt gattcatcca acaaaaacat aaacattcca
    11341 ttgatatcac ctttcatatc gagtaaaata catactactt tgttttctgg accaccaagc
    11401 aaatttgtcg cttcattata ttcaagtatc ttgaccatag gtattaatac ttctacattg
    11461 ctatttatca tggatgcaag tgcagtaatt gcattcccag agcctatatt accaatttct
    11521 ctaagagcat ctatatgaac atcatcaagt tctaaataat ttataatata aacccctccc
    11581 ttttattatt gcatttattt gcttttcatt gtatcagtgt atatttacac ttttatttta
    11641 aaacattatt tacaacttta actaatgttt ctgttttgaa gggcttcact ataaaatcta
    11701 acgctccaag ttttatggct tctacaatca tattctcttg tcctattgca gagcacatta
    11761 caaccttagc acttgaatcc aactttttta tttctcttag cacctctaaa ccatcttttt
    11821 ttggcattgt aatatcaagc aacatcaaat caggcttttc atatttaaat atattacacg
    11881 cttcttctcc atcatttgct tctattaaat tattatagcc acttttactc agagcttctt
    11941 taattatcat tctcataaaa atagcatcat ctactatcaa aattttattt tccataaaac
    12001 taactcctcc atatgtacaa caataaacgc ttttatcttc agttattgtc tatactatct
    12061 gactattttt cgctacacaa taaatacatt tcattgataa ataaaagtaa ttatttatgc
    12121 catattatac ttaattctct taacataatt tgtcaacaaa aaaacttata tatctattgt
    12181 aatatatgtt tggcgttttg acgagttatt aaaaatataa ttgtataaaa cataaaaagt
    12241 tatcaaaagt aatcaaatta taataaaaca actttatacc ttttttatgt ttgtataaaa
    12301 aattttttca gattcattaa aatcatttct gtagattcat ataggatttg actttctcaa
    12361 tatctaatag atagttgttt atttacttaa ttatatttct ctatatgtat tatcgattaa
    12421 attagattta gctttataca ttatttttta tatttttcaa attgtatact cataaatcca
    12481 gaagtattct aatgtgttta taatactttt tttcatattt taaattaaat aacaaatcat
    12541 tatatttaca agtatcattt atcaataaac aatattaaat gacgaatatg tctgaagatt
    12601 caaagtgata ctgatactat taattactaa aaaagcagta aatcttttac agatttactg
    12661 cttatagtta taaatagtaa aactatctat aataaatgta ctatactcaa tacttcattc
    12721 aatatagtaa taacaaatct actttattcc tatgtaaata tgaatttctt gtttctttgt
    12781 atcaaaagta ttacattgat actcttcaaa atcacttata taagtcctat caaaatccat
    12841 ttgccaaaac ttaaaccaaa aatctcctac ttctttttga cctcctacta taacaaactt
    12901 tgcatactta cctgctagta taactttact aataatactt tctccaacag tattattagt
    12961 gtttaattct tctaaattct tctctttatc agaattacta tttacttcac aacatgcaac
    13021 aaagctatac ggacttgtaa aatcaccctg gtaatctgta tatagaccta ttgtcttgtc
    13081 attcttttta ccctttatag cattatatat ccctttgccc ataaattttt tccacaattc
    13141 acctatagca tttaccgctt gtccatcttt atttgtagtc tccttcgata ttcctataac
    13201 tattttctca tttatctcta ctatttcata attcatactt tatacctcac tttgttttta
    13261 ttaatatatt ttattttgaa ctaattcaat tataatttat aatatacgac acctttatgt
    13321 catattttta atataattaa actcagtgag atattatata ctaaatgcaa gatattatat
    13381 atttaataaa atctttaatc tagcatcata ttataatgaa taaattttag acaactccct
    13441 tagtctagtt attacattat ccctaacatc tttaggttca agtacttcaa cattgtcacc
    13501 aaacgataaa atatatccat aaatccattc accaatagga aattctgtaa ttacatcata
    13561 tgtatcatct tcatttttag ttattaaatc cttattaaaa tcatcaaata ctctaaaaag
    13621 catcttttct ttaaacctca atttcaacgt tatagtattt tccttaatta ctttagaatc
    13681 attcaaacat acttcttcta ttatctttct tgaaaatact tcatccttta tagataaatt
    13741 ccttatccta ctaattctaa atatcctaaa atcatctttt agtttacaaa atccatacaa
    13801 gtaccaagtc ttactcttat acataagctt cagtggttcg acagttctgt ttgtctggct
    13861 tgacaaacta tttacataat taaaatttat agtattacgt cttaaaatag cttcttttat
    13921 ttttgtaaat ttatcatctt cattaaaatt acttccccat tcagtaaagt ctatttcaat
    13981 ccagtttgaa aaattctgct ctccaaatat tgagccaatt ttatttacta ctgaatttat
    14041 ttctggatac ttagtcgcct gtaatgtttt cagtgcaact attaaactct ctttatcttt
    14101 ttttgacagt atggccttgt ctatagaata ttcttctatt aaagatatcc ctcctccttt
    14161 gcctttcgtc atatatactg gtactcccga catagacaga gtttctatat ctctatatat
    14221 ggttcttgta gaaacttcaa acctatctgc caactcttta gctgttacta attttttatt
    14281 taatagaatt actattattt ctgttaatct atttattttc attcattacc acctactaaa
    14341 attattaaat ttatttaatc taaattaatc atactaattt ttaaataaat aaaatcttag
    14401 aatcttatct aaattattct tacatgattt tatttacttt ctattatctt tctcactttg
    14461 gatattatca tcttaattta tttattacta tatcaattta cttattatca tctcatttgt
    14521 tatcatctta cttaatttac ttatttctat atcaattcac ttattatcat ctcatttgtt
    14581 atcgtcttac ttaatttact tattgctata tcaattcact tattatcatt tcatttgtta
    14641 tcgtcttact taatttactt attgctatat caattcactt attatcattt catttgttat
    14701 catcttactt aatttactta tttctatatc aattcactta ttatcatctt aattcatttg
    14761 cttattatca tttactttat tcaatttcta tatcaaaaat tagtatttgt acttaatact
    14821 taaaattaat ttaaagtctt tacatattat ttattttcta ttgtaatatt catttccata
    14881 ctttactaag ctacttccac tcatttattt taaaatttca atttactatt tctcaactct
    14941 atattattat ttttcaattt tatattacta attttaaagc tttttagcta ttattcctac
    15001 aatatttaaa caattttttc ataataaagc tatattacaa tatattcaaa atatgtaata
    15061 ttttagatat ttttcgttga caatgttaaa tttttgtttt atccttaatt aaggacatgt
    15121 tattgacatt tctgaaactt atttgaaata gttttttcat tttatttagg aaaacgtatt
    15181 atacttaaga aaacgtattt tctcatttca gataagtaaa atatttattc ttttggggag
    15241 gaaatcatgg aaattaataa aaaacatttt attcaagtat ttttaacttg cttaatcttg
    15301 gtagtaatat gtgaatttat agggcaaaga actatagcta ttggaaaagc ctctatagta
    15361 ctgttcccta tgctttatgc agttataatt ggacttataa taacaccaga tttattaggt
    15421 aaaaaaatta aagcacttaa aaaagtggtt ggagaaaaag aaataaatat tgctggtgaa
    15481 gttgttggaa ttgcactagt aatgcttggt ataaaatatg gtactacagt tggaccaaac
    15541 attgacaaaa taattcaagc tggaccagca tttatcgctc aagaatttgg tcatatactt
    15601 gcaccaatcg ttgcattacc tcttgcatta atgtttggaa tgaaaagaga agctgttgga
    15661 gctactgcaa gtataagtcg tgaaccttct ttaggagtta tatcagaaaa atatgggata
    15721 aactcaccag aaggtagtgg tgtacttggt acatatttaa tgggaacagt tcttggtact
    15781 atatacttta gtgtactagg ttcaatatct atttatagtg gtcttcaccc atatgctttg
    15841 ggaatggcct gtggtgttgg tagtggaagt atgatgacag cagctgctgg ttcattatct
    15901 accatggtac cacctgaaat ggcagataca atacttgcct atgctgcaac aagcaatatg
    15961 atgtctagta taacaggaat tatattctta gtttttgtat ccttaccatt tactaatttt
    16021 atgtataaga ttttagaacc taaattttcg agaaataaaa aaactaaaga aattaaatct
    16081 acagaaggag agtgctaata aatgtttgct aatttaaatt taaagaaaag ttcatatcaa
    16141 ttattggtta tgtctgttat tggagttata attcttatag gacaaagaat tagcgttggt
    16201 acatctatag ttacagctct tcctggtatg gtgatgctaa tattagctgc tatggcagct
    16261 atgattataa aagatttatt tcctaaatca atctttccag cttttggatt tgcaactata
    16321 atcggccttt tacttagtat gccatatagt ccaacatctg aagtattctt aactaacact
    16381 aataatatta actttatggc tataactact ccactactag cttttgcagg aatttctgtt
    16441 ggaaacaaaa tagaagcttt aaaagaaatg tcatggaaaa tagttataat ttcacttatt
    16501 gtatttacaa ctatattctt tgcatgtgcg agtatagctc atatagtttt aagtattcaa
    16561 ggtaaaatat aggaggaatt tattatgaat aaagaacaat taaaatctct agtaataaaa
    16621 actatagatg aaaatagaga aaaaatatta aaaataggtc aaggaatata caaaaatcca
    16681 gaatatggat ataaagaatt taaaactaca gaagctgttt caaacttttt tgagcaagaa
    16741 ttaaatttat ctgtagaaaa aaatatagca gttacaggat gcaaagcaga tgcaaattct
    16801 agcaagaaag gtcctcatat atctatactt ggagaattgg atggtatatc atgtaaagaa
    16861 cataaagatg ctaatgaaat aggtgcttct catacttgtg gacataatat tcaaatagct
    16921 ggaatgttag gtgctgctgt tggtttagta aaaagtggcg ttttagaaca tttagatggt
    16981 aaagtatctt ttatggctac tcctgctgaa gagtttattg agttggaata cagagagcaa
    17041 ttaaaaaaag aaggaaaaat aacttatttt ggtggaaaac aagaattaat aaaaagaggt
    17101 tattttgatg atatagacat atctatgatg tttcatgctt ctgatttagg agaagataag
    17161 gctctagttg gtcctgagag taatggattt gttggaaaaa aggttaaatt tataggtaaa
    17221 gaatctcatg ctggttctgc tccacatgat ggaataaatg ctttaaatgc agcaatgctt
    17281 gctataaaca acgtgaatgc acttagagaa acttttaaag agtctgaaag agttagattc
    17341 caccctatca tcacaaaagg tggagatata gtaaatgttg ttcctgctga tgttcatatg
    17401 gaatcatatg ttagagctag aactataaat ggtatgattg atgctaatga aagaataaat
    17461 aaggctttga tggctggtgg aatggcagtt ggagctgatg ttgagataac tgaaattcct
    17521 ggatatcttc caatattacg atacaaaagt cttgataatt tatttaaaaa caatcttgaa
    17581 gatttaggtc taaaaggaaa agttattgat ggtggagatt ttacaggctc ttttgatttt
    17641 ggagatgtgt ctcatataat gcctactctt caccctatga ttggtggtgt aaaaggagct
    17701 cttcatacaa gagattttga aatagttgat gaagatttag cttacataat tcctgctaaa
    17761 gcaatggcac ttacagttgt agaccttctt tttgataatg ctaaggatgc taaagatata
    17821 ttagatacct ttactccagt tatgactaaa gaagaatatc taacattcct agaaaaacac
    17881 gataaaactt tataagtcta tttttataat agggtggtat ctactgtaaa agttatacca
    17941 ctctttgttt ttgtaacagt atacttcttt tcttttagct tttagattaa actaaaatat
    18001 attatcctcc ttaaaacttt tagagatacg ttaaaatatc agtagaacta tgctatattc
    18061 tttctaatta atataaattt atattctaat tcaaggtggt gaaaaaatgt ttaatgcagg
    18121 aaatcgaatt ataaatacat ggttgtaccc tattcaagat ggctttgtct tgattgatac
    18181 tggatatgaa aatggtttta aacatttcaa aaaacgaatt tctaaattca acataaaaat
    18241 caaagatatt cgatacatat ttctaactca tgctcatgat gaccatgttg gttttctaaa
    18301 tcagattcta gacgaatctc ctaatacaaa gattgttatg catgataaag ctttagaaat
    18361 tctatataaa ggtcaaaact cttttattgg tggttgtaac agccgtactg cctttctctt
    18421 ttgccaaatt atgaaactat ttggaaaagg tgagcatagt ttttctccac ttaaacaaga
    18481 atttgaaaaa aggtgtattc ttgtgtctga caagaatcgt aaagaaattg aaaaagaact
    18541 aaatggaaaa attatagata caccaggaca tactgctgat tcaatttcac tactaattga
    18601 tgatggtgtt ttattttgtg gagattctgc aatgaatgga tttccaagta ctcacaaaat
    18661 taccatattt gcagaaagca aactagaatt tattcaatct tggaaaacaa tcatcaatac
    18721 aaaacctaaa atgatttatc ctggacatgg aaaaccattt gaatacagta aattagaaca
    18781 aaatctaatc tatgtaaata aaataaattt atatcctcta cataattcaa aagatattca
    18841 cagatttttg tagaaaatac aaagtaaatt tctttgatta attaaaaaat ctaacacttt
    18901 actacgctac ttattttaat aacttaatct tccactagct tttcataaaa ttttgtttta
    18961 aaattaactt taaagtgcat atgctattta aatacattag atataattcg tcattaatct
    19021 acttaaagca tatttaacta acaccactca accagaaaat tcagaaaact gcattgacac
    19081 aggaaaaagt ttattttata ctttttttag gacatattgt ggacacgtct taaatcgaca
    19141 agcagaattt atattgtaag atcaaccaca atacttattt tttaattata tttttaaaca
    19201 ttagggagga tattatgaat gataacgtag ttaagaagaa aaactttttt gacaggacat
    19261 taaacagaat agaaactgtt ggtaataaac taccagaccc agttacaata tttttagggt
    19321 tatgtgtact tttacttata ctatctagtc tagttggttc tatggggata tcagtagttc
    19381 atcctggtac tggagaaact ataactgcag taaatttatt gactgtagaa cagcttcaaa
    19441 ttcttttagg aaacatagtt agcaatttcc aagggtttgc tcctttgggt ctagttctag
    19501 taactatgat aggtgctggt gtatgtgaca aaacaggact tatgacagca acaatcaaag
    19561 catcagtaag caagattcct gaaacaagag taactcttgt tgtaatgact ataggtatgc
    19621 ttgccaatat agcttcagat gcaggtacaa tattatttcc accattagct gcacttgtat
    19681 atcttggtgt tggtagacat ccacttatag gtttattttc tggatatgca gcagtctgtc
    19741 taggatttgc cgcaaacatt atgataagtg tcaatgatat acttgctgca agttttacag
    19801 ttccagcagc tcaaatgatt gattctggat ttcaagccaa tgcaacaatg aacttatttt
    19861 ttatgatagc atcaactttt gttctaatac ttttggcaac atgggtaaca gaaaaaattg
    19921 tagctcctag atttggtaaa tatgaaggaa atgcagaact agatgttgat ggaagtctta
    19981 gtgatgtaga aaagaaaggg cttaaaaaag ctggtataag tatattaata tatgtagcta
    20041 ttatagtagc tcttagtgta atcggtaaaa aaccattctt agctgaccca gaaacaggag
    20101 atttactatc aaacaatgct cctcttatga aaggtatggt acctataata gcactagcat
    20161 ttttcatacc tggtgttgta tacggaaaaa ctataggtaa aataaagaag gataaggatg
    20221 tagtctctat aatggctagt gcaatgagtg atatgggtgg atatataata ctagcatttg
    20281 ctgcttcaca atttttgcaa ttattcacaa atagtaattt aggtctgata ctagctgtaa
    20341 agggcggaga atttttaaaa tcagcaggaa taaatggacc tttattgttg ataggattta
    20401 ttatattatc atgttttata aatttattta taggtagtgc atctgcaaag tgggctattc
    20461 ttgcacctat atttgtacca atgtttatga tggttggata caatccagca cttactcaga
    20521 tggcttatcg tataggtgat tgtataacaa atccacttag cccattattt ccgtacttcc
    20581 ctattatact agcattcaca agaaaatacg ataaagatgc tggtatgggt actgtaattg
    20641 ctaatatgat accatactct atatcattct taatagtgtg gactatacta ttaatattgt
    20701 ttatggtatt taatattcca ctaggacctg gaatacttcc ttcatatagc atgtaattta
    20761 tttaaatctt tctaaaagga gaaataattt atgttagata aaaatagact tataaataat
    20821 tttatggata tggttagaat tgatagccca tctaatcaag aattagaaat gtctaagtgg
    20881 ttggtaaact acttaaaaga aagaaatata gatgccatta tagatgatgc aggtgaaaaa
    20941 tatggtggta atacaggtaa tgtcattgcc tatataaaag gtgaagaagg aagtagacca
    21001 ctttgtttat gtgcacacat ggaccaagtt caaccttgtt taggtgtaaa accaatacta
    21061 gatggtaatg tagttagaag tgatggaact actacacttg gtgcagatga taaagctgga
    21121 atagctgcta tacttgaagc tttagaacat gttactacag aaaaaatacc acatagagat
    21181 atttatcttt gttttacaat ctgtgaggaa gctggtatgc atggtgtcaa aaactttaat
    21241 cctgacaact tgccttgtaa agatatggtg attttagatt ctggtggagc tattggttcg
    21301 atagcataca aagctcctgc tcaacaatct ataaaaatct cttttcatgg aaagaaagca
    21361 catgctggta tagaacctga aaaagggtta aatgctatat tagtagcctc tcatgcaata
    21421 agcaatatgc acataggcag aatagatcca ttgactactt caaatatagg taaaatagaa
    21481 ggtggtggag ctacaaacat agtaactgat aaggttacat tgactgctga aattaggtct
    21541 catatacctg aaactttaga gtatgagctt aatcatatgg aaaaatgttg taaggatgct
    21601 gcatctaaat ttaatactac ttataccttt gaacatagta tgtcttaccc tagttttgaa
    21661 cttagtagag atagtcacgt tttcaagtta agtgaagaag caataagaca agttggtgtt
    21721 gttccaaatc caatggtaat tggtggtgga agtgacgcaa atatattagc taatcttgga
    21781 tataattgtg ctatattaag tctaggtatg tatgatgtac acacagttaa tgaatatgta
    21841 aatatagacg aattatatga tactgccaaa atagtttatc atatgattaa attataaata
    21901 tcataatata cctctttaaa ttataaaaat aaaaacctat gtatcttcaa ctttataagt
    21961 tatatattaa agttgtttta cataggtttt agtatcttat ataataattt attttaacat
    22021 ttttcataat aagctttggt attttatata gtaatttgtt ctaacatttt tcataataag
    22081 cttcaatatt tttcataata atttgttcta gcatttttaa taacaagttc tagtattttt
    22141 ataataattt gttctagtat ttttaataac aagctttagt attttacata ataatttgtt
    22201 ctagtatttt taataacaag ctctagtatt ttatataata atttgttcta gcatttttaa
    22261 taacaagctt tagtattttt ataataattt gttctagcat ttttaataac aagctctagt
    22321 attttatatt aataatttat tctagtattt ttaataacaa gctctagtat tttatataat
    22381 aatttgttct aatttttttc atgataagct ttaatacttt atatagtaat ttgttgtaga
    22441 attttataaa atataatgat ttatacagtt ttataaaata tcttaaaaca gtatttcagt
    22501 aatatttttt ggtcttcctc caccaatact agtctctttt gcacatattc gacctaaacc
    22561 tgcatttact attttattta atatacgtct tgcacttctt tcacttacat ttagatactc
    22621 tgctaactct tttgaatcat aaatcttact ttttctattc tcacttatag caataatttt
    22681 tgcaactgac tcacaactca ttccagtctt tttagatatt tctattacct tttcatcaga
    22741 tagcatcaaa gaataattta attcattttc ggaagctaaa ggtcctctta tattttcatc
    22801 ttcatctacc aaatatatac caatttcttt tgaatctatg gagtgtctta atgctttatg
    22861 tgcattattt tcagcctgat acgcagttac tccagtacca attcctatac taagagaaaa
    22921 gcccatgtct tttatctctc tctttagatt gaatagctta tcataattat actcattatc
    22981 agctacccct ttatgaacaa atacaacata atcatttctt ccaagtaaaa ataaggaacc
    23041 ttgaatgctt cttacatagt ttactacaag cttatccata tctgattttt ttatcatgtc
    23101 agaataatag ttatctatct tctctttata atctattaga ctcaatattt cgacagcaat
    23161 ttgagaaaat cttgccttgc ttagagcata ttcactcttt accttatcat aactttcttt
    23221 gattaattgt atagtagctt gtaaacgaaa tacaggatag cctctttctt ttaattcatt
    23281 atatactgca ccaaaaccag ttaacattat atccgtctta ttttcttcaa ataattttat
    23341 atgccattct acaagttcag actctcctac ttccaaagaa aatggattac aaaatacact
    23401 cgttgcttta atatcaaatt ctttaagtgc atcttccaca acatatctat caactacatc
    23461 tatactgaat ttatctaatt ttatatttgc actttttatt gcccaaaatg ccttcattat
    23521 actcgtccca cttctcggta caaatgaatg tggcttactt atctcatact tagattttat
    23581 aaattcataa actgcacatc ctgtaaatat aatagcatca cattcatctt cacatttaga
    23641 aataacttct attgtatcta ctactttttc tcttacatat attttagtct ttaaatcact
    23701 gtctatctgt tttaaatcat cctttatctt aaacccagag tctgaaggac ctataatacc
    23761 cactatcata aacttcgctc ctaatccata aatattatac tttttaaaaa ttatatcctc
    23821 actattttct acttctattt aattatgttg aactactcca tcctacctac atttagagtg
    23881 ggataattag cttatttttg ataaagtaac ttctcaaaat cagcacttgg aataggctta
    23941 caataataat aaccttgaat taccacacaa tctaaactca ctaaaaattc agcttgttct
    24001 tttgtctcta caccttctgc cactacatcc atatctaaat cttttgccat ggctatagtg
    24061 tgccttaaaa ctattttttc tctgtctgtg attccttcct cattaaagaa gccacaatct
    24121 atcttcaatg tatcaatatt aatatttttt aacatattta atgaagaata tgctgaacca
    24181 aagtcatcca tatttaaaac aataccatcc attctaaggt cggctattat cttagtaaat
    24241 aattttatat ttttaataaa taaactttct gtaagctcca attctaaaaa agattttggt
    24301 atactatatt tatttattaa acttaaaaca atttctttaa aatgtggatt atgcaaatgt
    24361 aatcttgata catttacaga gataggaact ggctcttcac ctaaatctat ccattttcta
    24421 atcaaagaac atacttgttc ccacacatac atgtctaatc tgataataaa cccattcttc
    24481 tcaaatagtg aaataaattt aattggaggt attatacctt tttctggatg aacccatcta
    24541 accaatgctt ccgcaccaac aattttattt gcattaagat tatacttagg ttgtagatat
    24601 acatggaatt gcccattttc aagtgcgtat tccatttccc tttccatctg tttttcttca
    24661 agtgcatcat ttcttatagt atcatcataa aatatatagt tattgatact ttgtttcttt
    24721 acttttttgt gagcatatcc tgccatttca cacgcatttg taattggaat attattatcc
    24781 aaaattttat aaaccccaaa acatggtact aacatatatt caaatttttt tctatttaag
    24841 ctatttttaa tcttataaat taatttatga acatctctat cagagtaact ctcataaaaa
    24901 atacaaaata catctgcata catacgacaa catataccat tagaaccaat gtttttttga
    24961 atcaattctg caacatatat taaagcctta tctcctcctc taactccata aatgtcatta
    25021 attaccttga acttatctat atccatcatt ataattgcat agctcttgtc aggatatctt
    25081 ttaagcatta aacttgtttg ttcacaaaaa ctttcataat tgtatagtcc tgttaatata
    25141 tccttttggt ttttatgtag ttgcataaga taatctatat tttttatagc aactaaaata
    25201 tgtgtttgtt tctcacctaa cttattttta ctactaatct ttaacatata aattaatgcc
    25261 caatagtact ttttatctat tcctaaacgt ctatactcaa aatttagttc taaatcgtct
    25321 tgcttgctgt tattaagact atcaagagat tttagaaggt ggttatcatc aaataatatt
    25381 atatcatcag gatgaattaa atgttttttt atgtatgaaa aagttttttc aagattttcc
    25441 tttataggaa aactaaaaat attgctctct gattgataaa ttggagtaat taaattagta
    25501 tcgatgcaaa tagataaaat tatatcatat gtattataag ctaatttttc ataagcctta
    25561 gaataccctt ttatcattaa atcatcaaaa taaaccttat caactaactc tttatgttta
    25621 aataaaatat tattcgtcga atcagctaag tcactaatta cttccatttc attatttcta
    25681 agtttgttct tattataata cctcttctta tcttggtaca ttctctcatc agcaacttta
    25741 attagcttat gtatatcaat attatcgtca ctccaaatac tgcccactgc tacactatat
    25801 atcatctcat ccttaaattc ttcacttaac caactcacta attcttcaaa tagttgtttt
    25861 gatatatctt cacataatac aataaactca tctcctccaa tacggtaaac attataagaa
    25921 tgaaagtatt tttttattat tacacatgct gacacaatag cagagtcgcc attagcatgt
    25981 ccaaagttat cattaatatc ttttaaccca tttatatcta caaatacaac tcctatggat
    26041 ttaaattttc ctttttgaaa attatctata tacttaatat atttgtttct attatatgca
    26101 ccagtcaaga agtcatagta gctcatataa tttaatttat tttctacttt tctttttttc
    26161 atctcagtta ataaaaaata agatagggat gtcaaaagag aggtatctcc aacagcctta
    26221 tgtggattat caactccaat aaaccctact actttatcat cttgttttag tgaagatgtc
    26281 attaaacttt caattttttg aggttttaaa atttcatatt ctattggctg ttcttctttt
    26341 atattttcta tatcatcaat tattacaaaa cccttttgtt cgaataataa aaaccaattc
    26401 tttaattcat taatatcaag atttgttagt gcctgttttt gttcatcaac accttcattg
    26461 caccattcat atgtattagt tacttttttt ctatcttctg atacttcaaa aacatatgct
    26521 ctatcagctt tatgaaattt accaatattg gttaatacaa gatttacagc atcagaaaaa
    26581 ttagattctg ttataagatg tttaatacat ccaactaata actcctttat ctctaatttt
    26641 tctgctattg acttacttat atcttccttt tctgtaatat caagagctat ttctaatcgt
    26701 gcatgtttgc cctcccattt aattaacttg tcctttaata taaaatgtct atttgttcga
    26761 gtattcgtat tttcccatat gtaatattca tcttctttta aaatagagtt tgtacaaaat
    26821 tcgcagggag aatctttccc ctgtaatgct ttataacatt ttacatggga tatatcatta
    26881 attcccattg cctttttccc aatttcatta atatataaaa gttcatatgt atctaaagaa
    26941 gaaacatata caatttcatc caactcatct attaaattta ttacatccat ttatatatat
    27001 ctccttttat tcattttcca gattgaattt ttaaagcttt taaaattttg ctatatattt
    27061 ggcaatgata ttatacttct ttatgtttta aaatagtacc ttaataaagt tctatttttt
    27121 agtaaataga attattattg tgtcaatcgt acaatagagt tttgtaatac ctaatttaat
    27181 atatttataa ttaactatct tattatgtgt ttacaattaa ttctcatata aatgacaaat
    27241 ctccacctca attaagtatt ccaatcatat atgaagataa tacttcattc atttaaaaat
    27301 ataaaactat tatatattaa aatttcttca ataataaatt atctagattg ttactttgat
    27361 atattatata atatcacaaa ggctgatata aaaagacaaa aagggtaatt tttttatatc
    27421 aaaaaaaatg ttaaattgat attatccata tataaattga tattatccat atagatgcta
    27481 tatttaacaa ttctacttac ttcccttaca cttattagca tatagttatt aagagtttgt
    27541 tgcaaaacaa cacttagcac actttaaaaa gtgtggtcta ataagtaatc aacgaagaag
    27601 acataataaa gcataaaata tgatatactt ttcctgtcat caaaactgat gattttacta
    27661 ttaatatctg ctaaaatatg cttaataaat taaattttag tgggagaata gttatgaaaa
    27721 tatttagttt cttgttgttt gtagtgggaa tatgtttttg tattgctgga tttatgggac
    27781 attacccagc atttgctggt gcaacattga gtttttttgc aactacaatg atagctgtaa
    27841 gacaagtcaa aactaagaaa aaatgaaata ggcaaatcct aactttacaa gttaatatta
    27901 cataagtaat tagtctaaaa ttggatactt tttctattac agaaatacat catccacttt
    27961 gtattctctt aaaaaaataa aatagctatg taaattcaag attagataga ttaactctct
    28021 atccatttca ttgtaaaata tacatagcta tttgtattcg atttaaaata cttagatttt
    28081 cttacataac aaataatttc tatctgatta ttactcatat tcatttagta atcactcagc
    28141 aactaatcat ttagtatcta ttcatccgcc atacggtaac ctaccccaac ctcagtcaaa
    28201 atatattctg gctgagcagg attcttttca attttccttc ttatacttgc cataaaaact
    28261 ctaagcgact gattttcact ttcatagtaa tttccccaaa ctttatctat tataaactta
    28321 tgagttaaga ctcttcctga atacttagac atcaactcaa taatcttata ttcgattgga
    28381 gttaaatgta tttcttcacc attaattgac acaatatgat tttcataatc tatctttagg
    28441 tttttaactt caaaagactt tggagcatca ttatttatat tatcctgttg agctttattt
    28501 ctaagagcca cacgtactct agccaaaagc tctgttacac taaaaggttt agttaaataa
    28561 tcgtctgctc ctccatctaa agcttccacc ttatccctct catgctctct cgctgaaaca
    28621 acaattattt tattagtctt tgcacatgcc ctaactcgtc ctattacctc aatcccatca
    28681 atatctggta gtcctaaatc caaaattatc aaatctgggt caagagaatg tataagtgat
    28741 atagctgttc ctccattatc tgtctctaca cacctataat tttgagtttc aagagatact
    28801 tttataaatt tacaaattgg cttatcatct tctacaatta gaactaatgg ctttatttcc
    28861 acttgtcttt cccctcctca tcatacatag gtatgctaaa tctaaatgta gctcctccag
    28921 aaggattatt aaatgcgaca atttctccac catgagcttc tactatagat ttacatatct
    28981 ccaatccaag accaatacct cttctttcaa gatttctaga cttattctta gtataaaacc
    29041 tattaaaaat attaccgata tcttcatttg gtattccttt tccattatct gcaacttcaa
    29101 atagcacttg atttgactct ttttttacag ttagttctat cttagaattt ttaggtgtat
    29161 gccttatagc attatcaatt aaatttacta acacttgttc tattaataat acatccacat
    29221 gaacgattat tatctcatct ggaatattgg tttttatgtc tctactattg gcaaactttt
    29281 tgactcttaa tatagattca gctattattt catcaacaac ttctggtcgt ttttcaatat
    29341 ccaatttccc ttcatctatt ctagtcatac taagtatatt ctcaacagaa tgagttagcc
    29401 aactcgtatc ttcatatata tttttcaata attctactct agtttcttta tctatcacat
    29461 catcattttc aagtattgtt gaagacgaac ccaatatact tgtaagtgga gttcttaaat
    29521 catgagaaat tgacctaagc aaatttcctc ttaatctctc tctctctgcc tcaagatttg
    29581 cttttttatt tttctcaaat aaattttctc tatcaattgc caacgcaacc tgtgttgaaa
    29641 ctgcttctaa tagtatcttt tcattttctg taataatatc tatcttaaaa cacgcaacac
    29701 ctataacacc aagaacattt gattcttgac cttttatagg gaaataatat gcactgctgt
    29761 ttttgcaata ttttgtccca attccaactg ggttacctgt cctaaaagct tcttttatag
    29821 cttctttttc taatactgaa tggaatatat tctcacttcc atcattgtta caaatataaa
    29881 tacttggctt acctagatta ttattctcat ctgcaatagt cactattaca gttctattta
    29941 atatatttac taaattagac ccacaaaatt caataatttg atttttattt tttgctttaa
    30001 gcaacgtttt gttattctca tagagcaatc ttatcatttt ttctctctta tgagaaagtc
    30061 tcacttctct ttttatccta gaagttaaag tacttgttat aattgctgcc attagcataa
    30121 tacaaaaagt cataggataa tcttttctat aagctaaaaa agtatataat ggatgcgtaa
    30181 agaaaaaatt aaatgatagc actcctatta ctgaagaaag tattccaaaa aaatatccat
    30241 aggttatact tgtagcaaat agtacaccta atatgtatac tagtataata ttagattcat
    30301 taaaacctac cttttcaaaa actactgata ttccagtagc aattgtcata accaatatag
    30361 tttttatgaa gtccttaata attatctttt tactgagata gccatcttca tcataatcat
    30421 actcttttaa gtcttcatgt tgtagtcgtt cctttttcat ttactacaat tcctccttat
    30481 tgttactgtt taaattggct ctattttata taatacaatt ttatcataat aaattcaatc
    30541 aatacattta attaatgtac ttaaattact aaaaggtgct gtcttaaaat gaaaataaat
    30601 ctctatttca aaacagcacc tatatattta aattactaat ttagttttta catacttaaa
    30661 tcaatagttt tattcaattt tataaattat aatacttcaa ttatggaaca tttctatcca
    30721 acaagcataa atataaagtg ggcacatata cctgcacaca aaccacctat ggtatgcgaa
    30781 agtatcgctt taccagccaa tggtcttgca tctaaagcat ccatcatacc tatgtgtgta
    30841 cttaaatatc cactccaaca catacccatt gctgtgaata ctgctatatc attaggagtt
    30901 atagcgcctg attttataaa ctctggtact aaagatattg ctgctccaac agctcctaat
    30961 gcagttacag ggaatgctat tgcctctggt gatgtgaatc caaataatgg ttctattatg
    31021 aagctaatct tatcaccaat agcaggtaat aattttatac cttcatatgc agctcctgtg
    31081 taaacagctt gacctgtagc agggtctgta gatggtccaa aagttaataa cataactaat
    31141 gtacaaacta ctaaaactcc tggtattata gccataccca tttcaacacc tagcttacca
    31201 ccttcaagta tagcatccaa tgttctttgg aatacattac catctcttat ttctctaaac
    31261 tcttcaagtt ttgcaccttt atcatttatt tgcttttcag tatcattttt agggtcataa
    31321 ttataatact ttttagtaaa agtcaacata attctaacac taataatact acctattatt
    31381 gccccaacat tacctattat agctggtagt acatattctt taccttgagc tatcataaaa
    31441 gttgttacaa taagtcccat accaaaggct gttcctaaat tacataaagc aggtacttga
    31501 tacttcttaa aatattgtgt aaatgttttg tctttagcaa atggtataat agctggatta
    31561 tcagataaat atgttgcaac tactcctgct atactagcac caggtaagcc ccatataggt
    31621 ctcataagac ccttaaatat cttattaact aaagatatta ctccaaactc tgaaagcaac
    31681 gcactaagtg cacctgcaag aactgccata gccattatta aaaatactgt gtctaataaa
    31741 agcgcatgtg ctgtactcat tattacttta aacatcattc ctgcacccat gatgcttcct
    31801 acatatccaa atcctaccgc caatagtaca ataaatacga aggtttccat acttactgcc
    31861 ttgactcttc tcttatccga cagcttttcc atcttgaaat cttccccctt ttaattttaa
    31921 attaaggttc ctaacattgg tacaaatttt ttggtacaaa ctgagttcta aaacttacac
    31981 tcgtaatgca agttgtcagt tttttgaaat aaaaaaaaat tacgtttata gaataagaat
    32041 atcctcttta atttggatac tcttattcta ttttatgtta ttatattatc atccttttgt
    32101 ttaaaagtca attttttcta tttttgttgt ttaattttat ttatactctt tttatatttt
    32161 tcattttctt ttatctttgt aagcactcca tataagttga cttttctaaa tacagtagtt
    32221 ataaatacca atcctaatgc aattgaactt gcacatgata atgtactcac cccatattct
    32281 acagctttta tataattatt ggtcaaaaca gaatacatag tattatatat tccataacca
    32341 ggtactaata ttattaaaca acaaacactt aatgtagttg ctggagtcat ataaattctt
    32401 gcacataact cacaatatat cgcaaaacaa actgtagcta taaaaaaaca taagttttct
    32461 gttactccca tatttaaaag aaatttatat gaaaaccaag ctatacttcc acctattcct
    32521 gctagtatta agttttttcc tttcatatta aatagcactc caaagcttaa ggcagtaaaa
    32581 aaagctgcta ttacttctat aaacaaatgc acttatatcc cccctaactt gaagtataat
    32641 ccaagtacca agaacattcc tactgctata gatacaccta caaaaaatac ttctgctaat
    32701 tttgcaagac cagaaatcaa ctgtccatct aacaaatctc ttaatgcatt agtcaaagca
    32761 agcccgggaa ctaagagcat tattgctcct gctattaaat ggtctaacgt ctttataaat
    32821 ccgagcttta aaattaaaat tgaacaagaa gctataataa ctgctccaat tgcatttaca
    32881 aaaaagtcat taagtgaaga tttacttaaa tacataataa caaacttagt cagaatccca
    32941 acagtaaatg cagctataaa ttcttccaca tttcctccaa ataatatcga aaaagttgct
    33001 gctgcaatac ctgcaaaaaa tattgttatt aaatccgagt aatagttatc ttcacttatt
    33061 tcatctaaaa ttttctcaca taattcaata tctaaattat ttatacttat tgctcttgat
    33121 aatgagttaa cttcatgaac caagtttagg tctactcttc ttgagcttat tcttttaatt
    33181 gctgaatgta atttcccatc tacaaataca gatgccatta cagctgttgg agttgcaaat
    33241 acatctacgt ggtctattcc aaaagattga catattctag ctatcgtttc ttcaactcta
    33301 taggtttctc ctccactttg caacatagct ttacctgcat ttgaggaaaa gtttaaaatt
    33361 ctatctatat ccacaaaaca tatctcccat tcttttatag tattattcat attttaatac
    33421 aagatattat ttatttaaac tattttaaat aattcatatc caatatttac attttatgaa
    33481 aaaacttgtt ttttatgctt gtcaaaatca aattttaagc ttgtttacac cataaaatgg
    33541 ctgaattaat atttgacaaa cactttcaac catttatata accttctaaa ttgtataact
    33601 ttttactaca aataaaatta tatctctttt aattctttct cttgagtatt taagcttata
    33661 gcaacttcat atttatatat gtacaatata aaacattatt tttatgatac aaaatataat
    33721 ttgtaaacgt atatatgtat taactgtgta tatataaatt attcttaacc ttatcagttt
    33781 tttcatatat cttcatctat atcgaccata tattaattac attgaccata tactaataaa
    33841 tgatattaca tagactgaag tatattaaaa aacttaaatt tagttattta acaacataat
    33901 actctaattt aatctataaa aatccatacc taatataatg caactcttat tttaacacca
    33961 tctattacac aaaacaacat attaaaaagt aaaatacaaa atatccacta taaaccttat
    34021 tttaatactg aatatatatt ataatatatt taatgtagct taaatatagt ttaaacataa
    34081 agaaaggaaa tggtatatgc taagaaaaga taaagttcta ttatctctac ataaattatg
    34141 tgaaaatatg actttaaaag accttcaatc agataaaaca ggattcacta caatagaaat
    34201 tgctaaccat tcatctcttg atagaagtaa taccagtaaa gaattaaata acctatataa
    34261 tgaaaaaaaa gttctgaaaa tatctggtaa gccaatttta tttctacatg ttagtattat
    34321 agaaaattta attggccgta ctttgaacag tgatgaattt tctataaata attgtaatga
    34381 gctacttaaa tcaagtaaaa atgactcaga agatattttt tcaacattac ttggacatga
    34441 ttctagtctt aaactaccta tagaaaaagc taaatctgct atactctatc ctccaaaagg
    34501 tcttaatacg ttactcatag gacctactgg tgttggaaaa agtacatttg ccgaaacaat
    34561 gtacaaatat gctgtagaaa gtaaaatctt ttcttctgaa agcaaattcg tagtatttaa
    34621 ctgtgctgaa tatgcagaaa atgctaactt attattaagt aatttatttg gttatgtcaa
    34681 aggttctttt actggtgcta ataaggataa attcggcata gttgcacagg ctgatggagg
    34741 catattattc ttagatgaaa tacacagatt accaccagaa ggtcaagaga tgctttttct
    34801 tttgatggac aaaggcatat acagacgatt aggagaatct gacattgtgc acaaagctaa
    34861 tgtctttatt gtgtgtgcca caacagaaga tatacattct tctctgcttg ggactttttt
    34921 aagaagaatc cctgttacaa tcaacctacc tgctttacag gataggtctt taaaagaaag
    34981 attatctctt attaaatact tctttattat agaatcaaaa tacaccaatg caactataaa
    35041 agttcacaaa gatgtaatta aatcattact cctttatgat tgttttggta atataggtca
    35101 gcttaaatct gacatacaac ttatgagtgc aagagccttt ttaaattaca aaactggact
    35161 taaggataat atagaaatag atttatccct tgttcctgat tacatctata ttggtctttt
    35221 aaaattgaat gaaaatcgta gtaatctaaa taaattatca gaacttgatt atatgctttt
    35281 ttatgaattt aatggtaata acttagaagt tgaatataca aaagaactat ctaaatacaa
    35341 tatagataca tcaaacaatg gatttaaata ctctacagag attccttatc tggaaaatga
    35401 tataaggagt atgtttataa attacatgga aaagtactct acaaaattac tttcgatatc
    35461 ttcagtaact cattctgatt atacaagtaa tgaaattttt aaagtaatca atccaaagat
    35521 ttactatgct gttgaacatt ctttaaaaga ggccgaaaaa atatcgagaa acaaatacac
    35581 aaaacaaact tatattgctc tttcaatgca tataagtgca cttatagaaa atataaatca
    35641 agacacctat aatcctaagt acaatttata taatgataaa attttcttag ataaagattt
    35701 aaatatatct aaaatagttt taagtataat tgaaaatgac ttacaaacat ctttacctaa
    35761 agatgaagta aaatttatat ccatgtttct aaatagcatg tatcttgaac caaacaatca
    35821 atctgaaagt ataggagtca taatacttgc tcatggaaat tcaacagcaa gcagtatgtg
    35881 tgatgtagca aattcattgc ttggtacaaa ccattgtaat gcaattgaca tgcctcttga
    35941 tgtaaaagta agtaccatac ttgataaaac tatagagttg gtaaaagaat gtgacgaagg
    36001 taagggtgta cttcttttaa cagatatggg ctctcttata gcttttggag aacttatttc
    36061 agaaaaaaca aaaatcaaaa ctcgctcaat tgaaatggta tctactccaa tagttttaga
    36121 agcagtaaga aaaagtacat taccagaaat gactttggat gaattagcta attccttaag
    36181 ctctttaaat ccatatattg gacgagcagc aatcgattca acagaaataa actatcctga
    36241 aaagtcaaga gagtatgtaa taataactac ttgtataaca ggatatggtt cagctatgaa
    36301 agtagcagac tttataaatt cttcacttaa aaatattcgt aaatacaata ttaatttagt
    36361 tcctcataat atagaaagtt ttaaaatgta taagaataaa tttagtaata ctaaaattct
    36421 ggcagttgtt ggaagtgtag attttaatgt agccaacacc ccttttatac acatagagga
    36481 attactaaat ggatatggcc tagatatgct aaacaaaata atagaaggta cattcaatgc
    36541 caatagtatt acaaatataa aagaaacaaa tctatcatac aacagtttaa taataaactt
    36601 tatgacccaa aacttagaac ttttggactc tgttaaatta ttcaactatg tcaattcttc
    36661 cttatttaca ataatagaat taatagatga aaacttaaag agcaaattta agctaggata
    36721 tatactacat tgctctttta tgatagaaag atgttttaaa aatacaactt ttccatataa
    36781 taacattact gaattaatta gtaaaaatca tgaactatat agtttaatac gtgaagcctt
    36841 taagccaaca gaagcttatt ttaatatttt gataccagac gaagaaattg cttatataat
    36901 agacatgatt aatgagtatc taaataaata aaatttatag cacttatttt gtgcatatta
    36961 attaatatat gaaatggagg acgagatttt gaaaggaaaa ataaaacagt taacaatact
    37021 tgcattaatt tttatattta taactcctgt atttgcattt gcagatactc caccagtacc
    37081 aaattcttca agagcagcac tacttataga ccaggaaact aaaagaatat tatttgaaaa
    37141 aaacattgat gaaaaaatgc cattagcgag tttaagtaaa atgatgacct ttttattggc
    37201 aatagaagca gttgataaga atcaagtaaa agagactgat atggtgaaaa tagacaagtc
    37261 tacagcttca gtaggaggtt ctacttgtaa acttaaagat ggtgatgaaa tatctctagg
    37321 agagcttatg cagggtctaa tgctagtatc tggaaatgat gctgctatag ccatagctaa
    37381 acatattggt aagactgaaa agaattttgt aaatatgatg aacaagaaag cagaagaaat
    37441 aggaatgatt gatacgtatt attttaatcc aaatgggctt cctatatata ctgacccaga
    37501 acataaagaa cctcctattg aaaatatgtc aactgctcac gatatagtta cacttggaaa
    37561 gtatatgtat gaccattatg aaaatcaagt tacaagaata accactatgc aagtatataa
    37621 tgatactaaa aaggatttta cacattataa cacaaatccc ctacttgttt cagtacctgg
    37681 tgttgatgga ataaagacag gctatacaga taatgctgga tattgccttg cattttctat
    37741 gatggtacct aaagatgcta aaaacgaaag aaatcataga ttgataggtg ttgtacttgg
    37801 tgatggtaac aagaaaaata gaatttcttc ttccgctact ttattgaaat atggtaaaga
    37861 taatttccat tctaaaaaga tagcacataa gggtgatatt atagagactc cttgtgttga
    37921 tggtattgat gattttaaga taacagttaa ggttgataaa gatttgtatg gtgttgtttc
    37981 agataacgaa aatatcaatc ctaaggtagt gtttaaaaat atgaattatc ctatccataa
    38041 gggagatatt gttggtgttg caaagtatta taatgactct ggtaaatttg ttggaagtgt
    38101 tgatgtaaaa agtgaaagta atataggatg tattcctttg aaggataaga ttaagattaa
    38161 ggttgctaag ataaataaaa aacttgagat taaaaattct gtttgtttta aagtatagta
    38221 aagcatacta ttaaaagagt atattaaatt tataaatact ccactttgtg gagttttttt
    38281 gttttttaca aaaaattaaa atagtggcaa caattgagga tgtgagggag agttgccact
    38341 attttgtata gggtattata ttatgttttt aagctagttt tactatcttc tatgtttata
    38401 taataactct tgtgtgtgaa tttaattgat aattaatatg aaaattatgt gaagttttga
    38461 tattaggtta tactttgaac tttatctaac attttaaatt ttatatctct aaattatcta
    38521 aaattactat atcaattaac tttacatgat aaaaaggctg tgtataaatt tatttttaaa
    38581 aattttactc acagccttaa attaaatttt ctatttaaag tatatataaa ttttattaaa
    38641 taatttgctt tttatttctt atttcataaa tcctagtatt cttgataaca ttaatgcaat
    38701 tgtagtaggt actttccctg cttcaaatgt agctgttgct gtgtttaatg ctgttactgc
    38761 atcatctatt tctttttgtg ttgcatctgc tttatctaat attgcttgtg cttcatctat
    38821 tgctgtttta tatgt
//
LOCUS       DAMJWO010000035        38359 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.036, whole genome shotgun sequence.
ACCESSION   DAMJWO010000035 DAMJWO010000000
VERSION     DAMJWO010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38359
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.036"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            1..391
                     /locus_tag="PC366_001809"
                     /pseudo
     CDS             1..391
                     /locus_tag="PC366_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            complement(751..1905)
                     /gene="nagA"
                     /locus_tag="PC366_001810"
     CDS             complement(751..1905)
                     /gene="nagA"
                     /locus_tag="PC366_001810"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDF2577339.1"
                     /translation="MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNITDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQRKS
                     KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFSVNVKNSVARLNSGSLAGSVLTMDKAVRNIVDWNIATLEDAIKM
                     ATYVPALSCNIDNVCGSIHQGMDADFIVTDKNFNIYETYISGICMYKVNK"
     gene            complement(1988..2713)
                     /locus_tag="PC366_001811"
     CDS             complement(1988..2713)
                     /locus_tag="PC366_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2577340.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRIQGKKPGTK
                     VLSFEVVESTKYFSEKLGITPGEKMIKIMRLRLADDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEIIKVADEEFSAGIISDKEAKLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            2982..3911
                     /gene="pfkB"
                     /locus_tag="PC366_001812"
     CDS             2982..3911
                     /gene="pfkB"
                     /locus_tag="PC366_001812"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDF2577341.1"
                     /translation="MITVITFNPSIDRMYKVNNINIGEVQRVVSKNATAGGKGLNVAK
                     VCKILKENPLAMGFLGGFNGEFIKNELRKLDIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGINIESREEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNEYNVYDVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLGEIDKYQDLVEVKKLS"
     gene            complement(4040..4957)
                     /locus_tag="PC366_001813"
     CDS             complement(4040..4957)
                     /locus_tag="PC366_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDF2577342.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     ICSDYRIMPFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVNQ
                     GEELIELSKKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVRFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKHFSVNTSMHRDSG
                     TKLEQVEILSKGKIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAINGEECIKAQRLLEKIINSVK"
     gene            5419..6588
                     /locus_tag="PC366_001814"
     CDS             5419..6588
                     /locus_tag="PC366_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2577343.1"
                     /translation="MKMFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEKL
                     NRFIDTISNNHGQFRVIFTGAGTSAYIGNSILPYLKNKNDIRKYIFEAIPTTDIVSNP
                     YDYLKKDIPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPQGELAKMTKND
                     ENNYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIIEMGRNVID
                     RKDEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKISTVYDSPMGFRHGPK
                     SFIDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFK
                     EKYNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            6637..7488
                     /gene="gatY"
                     /locus_tag="PC366_001815"
     CDS             6637..7488
                     /gene="gatY"
                     /locus_tag="PC366_001815"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HDF2577344.1"
                     /translation="MALVTTTSMLKKAQDEGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVKIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLDEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNRV"
     gene            7814..9715
                     /locus_tag="PC366_001816"
     CDS             7814..9715
                     /locus_tag="PC366_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2577345.1"
                     /translation="MRERIILETLKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFRGNRNITEYRNKFIDNLKLANIRSTIKNVLNEHDLEANLTELEEILAQIIILYIRV
                     SMRVVGNASNLKLYTEDLIIDKLLDKIFRDKKYNLNYDEKYYLKELIKLKTKDKKATI
                     KNIDKNKLQDIMFEFFREIDKKYNSNFLEDKEFFNLFYLHIACLIERIKKNHKIINPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIRNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESVRFADHIGNISSPKQYILGLFDKNHFRCIKDKAKYK
                     DILDSMSKCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDIIYENRVPKIIFMISLIKGNLELHKQISKYLSKIMANKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            9718..10761
                     /gene="ypdE"
                     /locus_tag="PC366_001817"
     CDS             9718..10761
                     /gene="ypdE"
                     /locus_tag="PC366_001817"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDF2577346.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELKAYSDKIICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLITIGGVKPLAQFVQKVRITT
                     KEGKKIPAVINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTSFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELRKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNQKQIDKGVMLMHRDRTLVPSRKMIDYVMEIADKNNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEQYKHIRNFI"
     gene            10776..11081
                     /locus_tag="PC366_001818"
     CDS             10776..11081
                     /locus_tag="PC366_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2577347.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPTMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            11178..11513
                     /locus_tag="PC366_001819"
     CDS             11178..11513
                     /locus_tag="PC366_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2577348.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            11545..12867
                     /locus_tag="PC366_001820"
     CDS             11545..12867
                     /locus_tag="PC366_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2577349.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGENNPISKFILNNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKVFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPVFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLAVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEDLLDDLGLDF"
     gene            12877..13947
                     /locus_tag="PC366_001821"
     CDS             12877..13947
                     /locus_tag="PC366_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2577350.1"
                     /translation="MNNTIERLVSLIYKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQILDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAMSI
                     QEYLSLKNEGFEINLITNELWKLRAIKSKEEIELIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVARKIIDKH
                     GFGEYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            13952..15139
                     /locus_tag="PC366_001822"
     CDS             13952..15139
                     /locus_tag="PC366_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2577351.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKESILKRASVGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVANNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDVKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETNIPKAKVMKSDSSFLAWIDVR
                     EVFRNEEESKEFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(15336..16208)
                     /locus_tag="PC366_001823"
     CDS             complement(15336..16208)
                     /locus_tag="PC366_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HDF2577352.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNILWDGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVSYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPFYKQNDFSKHYL
                     EFKSKNDVEKINLNGSFTDDIIPIGKLKNLHLNPEVFKNDALIYTNIDEVSIYNNDGS
                     KYVTISMEDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADSINSNKIYKDKKFINKLS
                     KGKVFTASYNINIH"
     gene            complement(16602..16793)
                     /locus_tag="PC366_001824"
     CDS             complement(16602..16793)
                     /locus_tag="PC366_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577353.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            17013..18059
                     /gene="cobT"
                     /locus_tag="PC366_001825"
     CDS             17013..18059
                     /gene="cobT"
                     /locus_tag="PC366_001825"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HDF2577354.1"
                     /translation="MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYT
                     YKNMATFDEIDMGR"
     gene            18091..18651
                     /gene="cobU"
                     /locus_tag="PC366_001826"
     CDS             18091..18651
                     /gene="cobU"
                     /locus_tag="PC366_001826"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HDF2577355.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCFDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFEHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIVG
                     RINQYIASKSNEVYFVVSGIAMKIKE"
     gene            18661..19434
                     /gene="cobS"
                     /locus_tag="PC366_001827"
     CDS             18661..19434
                     /gene="cobS"
                     /locus_tag="PC366_001827"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HDF2577356.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLIGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRDKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKVGFVYDIISNNSLWIIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSIIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLIFMFF"
     gene            19454..20068
                     /locus_tag="PC366_001828"
     CDS             19454..20068
                     /locus_tag="PC366_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDF2577357.1"
                     /translation="MIRLILIRHALTNDNKKGRLSGHINSCISEEGKLQINKITRYLS
                     NENIDKVYTTPSTRTKDTVEKISKLKLLEIEEKEALREISFGDFEGRTFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENDSNLDTKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLEIDGGFAVIDKMNFTDFI"
     regulatory      20135..20314
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            20444..21943
                     /locus_tag="PC366_001829"
     CDS             20444..21943
                     /locus_tag="PC366_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HDF2577358.1"
                     /translation="MLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMALNSFIT
                     KEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSSKYHDY
                     KLELVGVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPVIIVGD
                     IDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKVPVIGV
                     VPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVSIRYVD
                     YGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQMLGKK
                     LKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGKKVKGY
                     EIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEISFTRAI
                     LNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            21982..23358
                     /locus_tag="PC366_001830"
     CDS             21982..23358
                     /locus_tag="PC366_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HDF2577359.1"
                     /translation="MKKILIAGTNSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYKELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDASVPNADYIYIGGGFPEIFGKELEANESMRTSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLKKGNE"
     gene            23359..24330
                     /locus_tag="PC366_001831"
     CDS             23359..24330
                     /locus_tag="PC366_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HDF2577360.1"
                     /translation="MSILSIYIGYVTDLIVGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKFGGFILWFITVGITYLTTYAIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLNYNYRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYVSSFVSMLVFTLIHVLCRMILINLII"
     gene            24362..25432
                     /locus_tag="PC366_001832"
     CDS             24362..25432
                     /locus_tag="PC366_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2577361.1"
                     /translation="MKDLGHGANVGEMARLYGKNPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRENISKYIGINPDFIIPGNGATEVIYLLMKSVKKKLAIINP
                     TFSEYRRSAELNNLDIIDLELDLENNFKLNIDIIKENIKRFDSLFICNPNNPSGNVQD
                     LKELVHLLGKHNKVLIIDETFMEFVEDESKYSLVKYIESNKNIFIIKAVTKFFGMPGL
                     RLGYGLTSNTEIMNKIYEHKEPWTINSFADILSNFIFEDKEYIKNSKEYYIEERKYML
                     QELRNIRNIKVYDTDANFILIRAYKKTTKELKKDLLKQGNILVRDASNFIGLDDSFIR
                     VAIKSHEDNKILIENMKNLLGD"
     gene            25434..26321
                     /locus_tag="PC366_001833"
     CDS             25434..26321
                     /locus_tag="PC366_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HDF2577362.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSEVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKYTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVIILEPN
                     KVLDTMKIRLRQDYNKLKVENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     EKKEYLNEIIKISKKYGAYGVNIAHSGTVVGILIDKSMNDKKMIDTLCESNINSVYNK
                     IYTQNIINGGIKGEIEWNT"
     gene            26309..26941
                     /locus_tag="PC366_001834"
     CDS             26309..26941
                     /locus_tag="PC366_001834"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003724727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HDF2577363.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVDSIIDALKNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKEKGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAQESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            26950..28176
                     /locus_tag="PC366_001835"
     CDS             26950..28176
                     /locus_tag="PC366_001835"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HDF2577364.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLLLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVAKNDKNKGY
                     LTLKDIDSLSTNSECKSELYKFIRVYGGTGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRKLIGDNFESILGNDKVLKITIFAPQGETVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDEGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRVSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKVSAGIFNTHSKVADARSEILVANLALMGARYEFLN
                     KINQCVTTEEAVELINNSEYREVYNILSNKCKERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            28173..28781
                     /locus_tag="PC366_001836"
     CDS             28173..28781
                     /locus_tag="PC366_001836"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HDF2577365.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYLSKNIDNKMLNVVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKIPDFDYILSHKKVCMVTDSKIGPKQISREIIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRMDNFDMNVVVILDEE"
     gene            28771..29346
                     /locus_tag="PC366_001837"
     CDS             28771..29346
                     /locus_tag="PC366_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HDF2577366.1"
                     /translation="MRNSEFITGKVPITKEEVRAISISKLNLVNAKNLIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNIKKFNLKNIEVIKGYAPINLGLNVKVESI
                     FLGGTGNNLEEIIEWSKKNLVTGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            29339..30091
                     /locus_tag="PC366_001838"
     CDS             29339..30091
                     /locus_tag="PC366_001838"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HDF2577367.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSKLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            30075..31196
                     /gene="cbiG"
                     /locus_tag="PC366_001839"
     CDS             30075..31196
                     /gene="cbiG"
                     /locus_tag="PC366_001839"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HDF2577368.1"
                     /translation="MNIEGNIAIICITENGKNLAVKINSLVNNCVIYQVKNKKSNLVV
                     EETCVHTVQKKLSDFVGEIFSKFDYIIFIMATGIVVRSIAPYIISKFSDPAILVMDEK
                     GKNVISLLSGHIGGANSLTQYISSLIDANPVITTATDINQKASLDMIAKKLNAHIDNF
                     RESVKEVNSMLVNNKCVGLYVDEGYQVDTRGFKLIESKDELRDSFSNTYIEKLVVVSN
                     KINCIEDIENLNLDNKFEHCYSTKKIIKVIPRDIVIGIGCRRNTDSELMYNSLEEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKILKVPFKTFSIDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPIAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            31193..31918
                     /gene="cobJ"
                     /locus_tag="PC366_001840"
     CDS             31193..31918
                     /gene="cobJ"
                     /locus_tag="PC366_001840"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011701973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HDF2577369.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     GKEIIQNGMRQEVDRCKQAVEEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKGGDTPVGVVKDVGREKEEKFVCTFENMDFEKVDMTTM
                     VIIGNKSTYINGELMITPRGYTV"
     gene            31915..32667
                     /gene="cobK"
                     /locus_tag="PC366_001841"
     CDS             31915..32667
                     /gene="cobK"
                     /locus_tag="PC366_001841"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HDF2577370.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAE
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKTAITCAKLLNIDYIRFERKSL
                     IEEIDYDNKFIVDTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIVAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            32686..34164
                     /locus_tag="PC366_001842"
     CDS             32686..34164
                     /locus_tag="PC366_001842"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HDF2577371.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSHDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESNEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGINAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEEDGFDVRVHLKGLGENSYIQDKFVRHAVKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            34194..35099
                     /gene="hemC"
                     /locus_tag="PC366_001843"
     CDS             34194..35099
                     /gene="hemC"
                     /locus_tag="PC366_001843"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HDF2577372.1"
                     /translation="MNIVVGTRGSTLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPHGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSTIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            35089..36588
                     /gene="cobA"
                     /locus_tag="PC366_001844"
     CDS             35089..36588
                     /gene="cobA"
                     /locus_tag="PC366_001844"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HDF2577373.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLR
                     EAKPDCELIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEDIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLEKISENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVGLREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNINLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELAPILNDNDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEDKKGEILDILNSNDIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTETINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            36605..37570
                     /gene="hemB"
                     /locus_tag="PC366_001845"
     CDS             36605..37570
                     /gene="hemB"
                     /locus_tag="PC366_001845"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HDF2577374.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     NSLPDVYHLSIDMLEDEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINSDINVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGADMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKK"
     gene            37723..38301
                     /locus_tag="PC366_001846"
     CDS             37723..38301
                     /locus_tag="PC366_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HDF2577375.1"
                     /translation="MLYPINLKLDELDVVIIGGGEVAYRKCKNFLEFNKNVTIVSKQI
                     LNKFYDLKGNIKIIKDDYKEIYIKDASVIIAATNNRELNMEIGLYCRAKNKLVNVVDN
                     IEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEERYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLVTLDLEELKKFDI"
BASE COUNT        15289 a         4047 c         6817 g        12206 t
ORIGIN      
        1 tgcaaaagat taaaagaaag tatatgctgc aattacagag gaagtagcat taagtgagct
       61 atcgctctta gaggaaaaat ggggtaatca atatgcgata gcattaagaa gttggcgaag
      121 caattgaaat gagctagcaa catactttaa atatcctcaa gagataagaa cattgatata
      181 tactacaaat tcaatggaaa gttacaatag attattaaga aaagttacta aatcgaagtc
      241 tatttttcct ttagatgatt ctttgcacaa atcattatac ttagcaacta tggatatttc
      301 tgaaagatgg actcaaaaga ttagaaattg gactcaaatc ttagctcatt taagtattta
      361 ttttgaagaa agaattttaa ctctaaatta ataaagaaat atttcaaaaa aattaaggaa
      421 ttttcttaaa ggggtaataa tttttacaaa aatggaaaaa atatcaaaat aaggctatga
      481 tttttaaagc catagcctta ccaataaatg tttaattatc actaaaaaat aaatttttat
      541 tcaaagaata cacataaata tttccagatt cttaatttta taaacttata ttgtaaaata
      601 aagaacctta ataaaaggag tgtctcaaaa ttaacttttt agtttatgag gcactctttt
      661 tgtatgaaat caaatgtatt ttcatcattt taacaatgaa aaagagactt atctctattt
      721 ttaggaagcc tccataactt tatattgaat ctatttatta actttgtaca tacatatacc
      781 acttatataa gtttcgtata tattaaagtt cttatctgtt actataaagt ctgcatccat
      841 accttgatgt atggagccac agacattatc aatattacaa cttaaagcag gaacatatgt
      901 agccattttt attgcatctt ctaaagtggc tatgttccaa tcaactatat ttctcacagc
      961 cttgtccata gttaatacac ttccagctaa actcccacta tttaatcttg caacactatt
     1021 ttttacattt acactaaact taccaagagt atattttcca tcctccatag caccagccct
     1081 catacaatct gtaattaaag ctatgttatt actagacttc gcatccatca ttattttaac
     1141 agctattggg cttacatgat gaccatcaca aattaattca gcataagtat cttttagtac
     1201 catagcagcc ccaaccattc caggttctct atgatttaaa gggctcatcc cattatatgt
     1261 atgtacaaac actttagcac ctgaattaac gacttgttta acttgttcaa atgtagctga
     1321 actatggcca agagaaacag agatattatt tttagttgca tatcttgtta attctattga
     1381 acctttacgt tctggagcaa ttgctatttt tcttattaaa tttttcgatt ttctttgcca
     1441 taattttaat atattgatgt cagggtcttt aaaatatttt tcattttgag cgcccttata
     1501 tttttctgta aaaaatggac cttctaaata aatcccttgt atttttgcac cctcaactcg
     1561 attgaagcta ttgcttatat tttctacaga atcacttagt gtatctacag aatcagttaa
     1621 agttgtaggt aggaaagatg ttactccata ttttaataag ccttttgaaa ttgtgtttat
     1681 tgcttcaaat gtattgtcca tgacatctgc acctaaaaga ccgtgaatgt gagtatcaac
     1741 taagccagga gcaatatatt tacctgaaaa atctatgaca ttatcagtaa tattaggtct
     1801 ttcttgttga aattcaccga atttgccatt aattatacta aggtaacctt tttctttgat
     1861 tccatgtttc ataaaaaatt tatctgcata aataaaactt ttcaaaataa cctccttata
     1921 attatactat cattgtggca ttgacgttta taatatcatt ctattttctt gaaagctatt
     1981 taattcacta tcttacatgt cttactctat atacaaattt atcgcttcta gcaacactca
     2041 aagtaaattc aataactata ttgtcatcat tatatgtggt acgaagtaat ttcagacaag
     2101 gtgaatctcc tggtacttcc aataacttag cttccttatc agagattatt ccagctgaaa
     2161 attcttcatc agcaacttta ataatctcgc cataatcttc tctaaatatt tcatataaag
     2221 gtttttgttc gattttttct tttgtcaatc ctataaattc tttcatagga agatatgttc
     2281 tttcaagcat cataggaagg tcatcagcaa gtcttaaacg cattattttt atcatttttt
     2341 caccaggagt tatacctaat ttttcagaga aatactttgt actttctact acctcaaatg
     2401 ataatacctt tgtacctggc ttttttcctt gtattctcat ataatctgta aagctataac
     2461 tttccattaa gttttgagaa ttttgactta gtgcagcaac aaaagttcct tttccatgtc
     2521 ttttgtatat atatcccata tgttccaact cagccatagc tagtctaact gtggttctac
     2581 ttactccata ttcatcacaa atttttcttt cagaaagcat tctatcgttt ggttccatct
     2641 cattttcaat cttagttctt aatatctcaa caagctggtc atatattggt cttttatcat
     2701 ttctttttat cataaaaaca tagtcctttc taagtggtta ttaccacaat ttgattatag
     2761 aatatagaat tatttatgtc aatgaataaa gtttaatcaa aattcaataa gtaaggctat
     2821 taatttatta taaaattatg gtatattgac aaaacaagta aaataattta tattcaaatt
     2881 ggtaataacc actttgggta tattatagat gaggtatttt ttattttaca gattaattta
     2941 ttgtttagaa aagtaaaaat taataatgag gagaatctag tatgattaca gtaataacat
     3001 tcaacccatc tatagataga atgtataaag tgaataatat aaacataggt gaggtgcaaa
     3061 gggtagtaag taagaatgca actgctggag gtaaaggatt aaacgtagct aaggtatgta
     3121 aaattttaaa agaaaatcct ttagctatgg gatttctagg tggatttaat ggagaattta
     3181 taaaaaatga acttagaaaa ctagatatac aaaataaatt tacaaaaata gagcaggaaa
     3241 ctagaaattg cttaaacata attgaggaca ataaagttag tacagaattt ttagaaaaag
     3301 gaccaatagt agaaaaaagc gatttagaga gatttgaaaa tgatatagag gaagtactaa
     3361 aaaatactaa aatactagta gcttctggta gttattgtga gaatatgccg atagattatt
     3421 atgaaaagat aggaaatata tgtagagcaa ataatataaa atttatatta gatacatcag
     3481 gagaagcatt aaaaatagct ttaaaatcaa aaccatattt aataaagcca aatatagatg
     3541 aaataagaca tttattagga ataaatatag aatcaagaga ggaaattatc ttgtcaggaa
     3601 aaaaacttat tgaaatgggt gcagagaatg tatgtatatc tttaggaaaa gatggtatgg
     3661 tgtatttaaa cgaatataat gtatatgatg taaaagtacc agttgtaaag tgtataaata
     3721 ctgtaggtag tggagatagc acagtggctg gatttagtgt aggtatttta aggggttata
     3781 aaatagaaaa tttacttaaa tttgcaaatg cttgcggtat aagtaatgct ttaaatatgg
     3841 aaactggatt tgtagatttg ggagaaattg ataaatatca agatttagtt gaagtaaaaa
     3901 agttaagtta aataaattta atgggaatat aataaattta atgttgttgt aatagatttt
     3961 aattttaata taaaagatat agtcttatat aaaaataggt tagaaaaatt catttttaac
     4021 ctatttttat aataaatatc tattttactg aatttataat tttctctagt aatctttgag
     4081 ccttgataca ctcttctcca ttaatagctg gttttatatt attttctata caatcaataa
     4141 aatgatttga tatatcctca aaaccctttt gttttaatat atttacccat gcaccacttt
     4201 gttttaaagt taggtttcca ccttcttcta tttccagtac attaagattc ttaactcttt
     4261 gaatcttacc ttttgaaaga atttcaactt gttctaactt tgttccagaa tctctatgca
     4321 tagaggtgtt tacagagaaa tgtttacctt taagtttatg acttacaaat ataagattct
     4381 tattgtctgt taaaaataaa tcttctccgc taatttcaac atcttcattt gctaaccata
     4441 aagcagtgtc aataacatgt atatagtcat ctataagggt actgtcgaat ctaacatttc
     4501 ttaaggaatt taatccatgt ttacatatat tgatagatac gatttctgta gcattatttt
     4561 taatttcttt gtacatagga cagaatctac ggttgaatcc aaccattaaa tttaagtttt
     4621 ttttcttact taactcgata agttcttctc cttgatttac tgttgaagca agaggtttgt
     4681 ctacatatac atgaacacct aaatttaata atatttttat aatttcgtag tgtgtttctg
     4741 tagagctatg tagaaaaata caatcacatt ttttagctag ggattcaata gaatcgaatg
     4801 gcataattct ataatcacta cagatttttt cccttttaac tttatttgga gtaaaagctc
     4861 ctacaaactc aaatctctca gacttagtta atataggtaa atatgccttt tgagctatgg
     4921 agccaagacc tatcattccc atttttatat ttttcataat actttctcct aaggttttta
     4981 tatttacaga attgattata attcagacac ataaatttgt aaactttgta tcaaaaaata
     5041 aatttaaagc ttatataagt aaattaacga aataagaaat attgacaaag taattttgta
     5101 ggatatctat aaaattgatt gatataaata ttttatgtat tgacaaaaaa ttcaaattaa
     5161 tttatatttg gattagtggt aattaccact ttggtctgaa caagttttta tcgtaaaata
     5221 aaaatactaa agtatgattt tattaaattt ttaaagataa actataaaat taattaaaat
     5281 ctatagcgta tattttatag tgagtttaag tagtactaaa aaatctaagc aaaaaattat
     5341 aaaagagtat atttttttat agtttaaagt ggttataacc tcattaccaa atgtaaacgt
     5401 tacaagtatg aaaggagaat gaaaatgttt aaattagaag aacaaaaact aaaagattta
     5461 ggtgcaataa taacaactaa tgaaataaaa caacaacctg agttatggtt agagacttat
     5521 gaaatatata aatctaacaa agaaaaatta aatagattca tagatacaat aagtaataat
     5581 catgggcagt ttagagttat atttacaggt gctggaactt cagcttacat aggaaattca
     5641 atacttcctt accttaagaa taaaaatgac ataagaaaat acatatttga agcaatacct
     5701 actacggata tagtttcaaa cccatatgat tacttaaaaa aagatatacc aacattatta
     5761 atttcatttg caagaagtgg aaatagtcct gaaagtttgg ctgctttaaa tttagggaat
     5821 aagattgtag ataattttta tcatttagct ataacttgta atccgcaagg agaactagct
     5881 aaaatgacta aaaacgacga aaataattac ttgttattaa tgccatcaaa atcaaatgat
     5941 gaaggctttg ctatgacagg aagtttttcg tgtatgatgt tatctgctat gttaatattc
     6001 gatagtttag aagatgatgt agaaaagtca tatataaatg caataattga aatgggaaga
     6061 aatgttatag atagaaaaga tgaaatacat gagttaataa ataaagattt cgatagagtt
     6121 gtatatttag gttcaggagg attaggtggt ttgacacaag aagcacaact aaaactttta
     6181 gaacttacag caggaaaaat atctacggtg tatgattctc ctatggggtt tagacacgga
     6241 ccaaaatcat ttattgatga aaatacactt gtatttgaat ttgtatctaa ctgtttatat
     6301 acaagaaaat atgatttaga tgttttagag gagataaaaa gggataaaat tgctaaattc
     6361 acttgtgcag tgtcagtaga aaatgaaaat aacttctcag gaacaaagtt tgagtttaaa
     6421 gaaaagtata ataaattacc agatgtgtat cttgcaatgc catacatatt gtttgcacaa
     6481 actatagcat tgtttgtatc ggtaaaggtt ggaaataagc cagatacgcc atcagctaca
     6541 ggaacagtaa atagagtagt aaaaggtgta acaatatatg aatattaaaa gataagatta
     6601 aaatattata actaaataat ttgggagggt atcaatgtgg cattagtaac aacaacatca
     6661 atgcttaaaa aggcacaaga tgaggggtat gcagtaggag catttaatgt agaaaatatg
     6721 gaaatggtaa ttgctgttat agaagcagct gaggagttaa actctccagt aatattacaa
     6781 actactccat ctactgtaaa atatgcaggt cttgattatt atctagcaaa tgcaaaggtt
     6841 gctgcagaaa gagtaaagat acctgtagca atgcatctgg accatggttc aagttttgac
     6901 cttgcaatga aagctttaag aagtggatat acatcaataa tgatagatgg ttctcatgaa
     6961 agctttgaaa ataatatatc tatatctaaa tcagtagtaa aagcatgtag tccttctctt
     7021 ataccagtgg aagcagaact tgggaaagtt ggtggaaaag aagatgattt agatggcggg
     7081 aatagtaatg attatacaaa tccaaaagag gcaaaagagt ttgtcgatag aacaggaata
     7141 tcttcattgg ctattgctat aggtactgca catggattgt ataagggtga acctaaaata
     7201 gatttagata ggttatcaga aattaaaaat gtagtttcaa tacctttagt attgcatgga
     7261 ggttcaggaa tacatgatga tattataaaa gaagctataa aaagaggtat tgcaaaagtt
     7321 aactatgcaa ctgaattaag aattgcatat agtaaagggg ttaaaaaagt tttagatgaa
     7381 gattctgagg ttatagaccc taaaaagtat ggattagcag ggcttcaatc agtgaaggat
     7441 tttgtaaaag aaaagattaa agtgtgtggg tctgtaaata gagtataaaa ataaaatatc
     7501 ctaaatttat tttagataag tttaggatat ttgttatatg aaaaatttat attaattata
     7561 tgtaaatggt gtattttttt catttaattg atgaaaaata tcagctttta ttggtaaagt
     7621 attacatata taattaaaat ataataaaaa ttgaactata tattttatta ttataaaata
     7681 tgtatattaa attttggaat caaaatatac taggatataa aattcttaaa taaaaagaaa
     7741 aggttgtttt tataaaaaat attttttata ccactttaaa aaacacaata ataacactga
     7801 gggaggtggg gatatgagag aacgcattat tcttgaaaca ttaaaaaata gtagtggtta
     7861 tctaaacata gattattttg cagataagtt gggggtatct actcgaacta tcagaaatga
     7921 aataaaaaag atagaaacta taaaagaatg taatggtttt aaattagaat ataagtctaa
     7981 attaggatat attctaaata ttaaagacca agataaattc gagcattatc taagaaactt
     8041 accctcagat ttagttgaaa atccagaaca acggttggag tctataatag tagagctttt
     8101 agtaaatgaa ggttataaaa ctatagaaca gttaagtaaa aaatttctag taagttcatc
     8161 ccaaataaaa aatgatttaa aaaagataga tgaaaagata aaggatacag aattaaaact
     8221 agagcgaaag gctcattatg gaattaaaat agaaggttct attaaagaaa ttcaaagtat
     8281 attggtggat agttatttta gagggaatag aaatataaca gagtacagga ataagtttat
     8341 agataattta aaattagcta atattagaag tacaataaaa aatgtactta atgaacatga
     8401 tttagaagca aatttaacag aacttgagga aatattagca caaattatta tattgtatat
     8461 aagagttagt atgagagtag tgggaaatgc tagcaattta aaattatata cagaagattt
     8521 aattatagat aaattattag ataaaatttt tagagataaa aaatataacc ttaattatga
     8581 tgaaaagtat tatttaaagg agcttataaa actaaagact aaagataaga aagccactat
     8641 aaagaatatt gataagaata aacttcaaga tattatgttc gaatttttta gagagataga
     8701 taaaaaatat aactctaatt ttttagaaga taaagagttt tttaacttat tttacttaca
     8761 tattgcatgt ttaatagaac gtataaagaa gaaccacaag ataataaatc ctttttcagt
     8821 taaaataagt caacagtatc caactgtttt taatttatct attcaatttt caaaaatcat
     8881 agaaaatgag tatcatataa aaataagtca agatgaaata gggtttatag ctactcacat
     8941 tgctgttcct tttgaaaaga gagaagaagc taattttaat aaaaaatata aaatagcaat
     9001 aatatgctct tctggtggag gtagtgcatt tttgataaat ttaagactta aagaaatttt
     9061 tccaaatgct gagataagaa atttttcatt actagaagaa aaagctgtaa tagaatttgc
     9121 accagatttg attttttcaa taacaaatct tttatttgaa ataaatgctc cagttatact
     9181 tataaatgaa attttagacg aattggatta tttagatatt aaagaaagtg ttagatttgc
     9241 agaccatata ggaaatatat caagcccaaa acaatatata ttaggtctat ttgataagaa
     9301 tcactttagg tgtataaaag ataaagctaa gtataaggat atccttgata gtatgtcaaa
     9361 atgtatagtt gacgagggag cttgttctcc aacctatccc aaagatgtat gggaaagaga
     9421 aagctatttg agtactattt atacaaatgg ggtggctata cctcatccaa tcgagatgac
     9481 aggaaacaaa aatataatat cagtagcttt gatacaaact gatattattt atgaaaatag
     9541 ggtgcccaaa attattttca tgatttcatt aataaaggga aatttagaac ttcataagca
     9601 aatatctaaa tatttaagta agattatggc aaataaggat atggtagaca tgctaaataa
     9661 gtcacaatct tatgaagagt ttatgtataa gttaaaaatc tatctgggag gttagacatg
     9721 aatatagagt tttttaagag gttgtcagaa gcagatggta tagcatctaa tgaagaagag
     9781 gttagacatg ttttattgga agaactaaag gcttatagtg ataaaattat ctgtgatggg
     9841 ctagggagta tcatcttttc taaaataaaa gatgagagtg caccaaacgt aatgatttgt
     9901 gctcatatgg atgaagttgg atttatggtg agaagtatag acaaacttgg tatgattcac
     9961 ttaataacaa taggaggagt aaaacctctt gcacagtttg tacaaaaagt tagaattaca
    10021 acaaaagaag gaaagaaaat ccctgctgtc ataaatgcta catataataa tggtaaggct
    10081 gaaaatatat atgcagatat tggagcatat acagaagaag atgtatataa cctagggatt
    10141 aatgttgggg atatggtaac atatacaaca agttttgagg aatttacttt accagaccga
    10201 ttagtgggaa aggcttttga tgataggata ggatgttttg tgatgggaga agttttaaaa
    10261 gaacttagga aagaaaatct aaattgtaat attcactttg cggctacaag tagtgaagag
    10321 gttggaataa ggggagcaaa gacatcaaca cagttaataa atccagatat agtatttgta
    10381 atagatgtag catgtgctaa aaatgagttt gtgagagact atacaaatca gaaacaaatt
    10441 gataaaggtg taatgctaat gcatagagat aggactctag tccctagtag aaaaatgata
    10501 gattatgtaa tggaaattgc tgataaaaat aatataccac ttcaacatga tatgtttgaa
    10561 tcaggtggga ctgatggagg agaagcacat ctcgtaaatg aagggaaacc ttgtgtagta
    10621 acttgtgtac cagttagata tggtcattgt gcattttcaa tagtaagtaa taaagattta
    10681 gagaacatta taagattgta tacacagtta attttaaatt ttgatgaaga acaatataaa
    10741 catataagaa attttatcta aaggagaata agaaaatgtc aacagaagta caaataatgg
    10801 agcttatatc aactgcagga gagagtaaat cgaaagcttt tgaggcttta aaaaaagtaa
    10861 agtcaaaaga ttttaaagga gcaaaattgt taatagagga ggctcgtaaa atagatattg
    10921 aggctcacag aatacagaca gaattaataa ctcaagattt aaatgaagat gttgaaagcc
    10981 caacaatgag tcttttaatg gtacatgctc aagaccacta tatgacttct cagctagcaa
    11041 aagacttgat agaggctttg atatattgtc tcgataagta attgtaatgt agaaatagat
    11101 tatttatgta aaaattcttt taaaagttta gatgctttta agagataata aaaatacaaa
    11161 ctttaggagg aattattatg aaaatattat tatgttgtgc aggtggattt tctactaata
    11221 tgttaatgca aaatatgaaa aaggtggtaa aagagagtgc taaactcaat gaaaaagatt
    11281 ttgagtttac agctatacca gcagattcaa tagaaagtga agttgatgat tgggatatag
    11341 tacttatagg tcctcaaata gctcataaaa tagacttctt aaaaggaata ttagagccaa
    11401 aaaataagcc ttttgcagta atagataaag atgtatatgg aaaaatggat ggagctacag
    11461 ttatgaagtt ggcattaata acttataaga aacatcaatt agctcaagga taataaaaat
    11521 aatgagggaa aagggagatt agatatgttt tcaaaatttg aagcatttat gaatagagta
    11581 tttatgcctt tagctcataa ggttgacaat caacgtcacc ttggttctat aaaggctggt
    11641 atggttgcta tgacaccatt cacaatatta ggaagtatat ttgcaatact tccagcactt
    11701 ccaaatatgc ttggagaaaa taatccaata agcaaattca tacttaacaa ttcagcaata
    11761 ttggatttac cagtaagtct ttccataggt ttaataggat tatatgcttg tatgtgtatt
    11821 gcttttaatc tggggaacta ctataaatta tatataccag gttgtgttgc actatcaact
    11881 ttttcttttt tattcctagt agcctcattt acaccagatg gagctttaga aataggaaat
    11941 ttaggagcta aagggctatt tacaggtatg atagcagggc ttggttctgt ggagttatat
    12001 aatttttgta ataagaagaa tatcacaata aaaatgccag aaaatgtacc tgattttgta
    12061 tctaggtctt ttgaattaat acctactact ataatagttt gtggaacttt tatagttgct
    12121 cgttttattt cattaaaagt atttggagaa ttacctccac agatacttac tcaattttta
    12181 tctccattag taggaagtat ggataaccca tggtcagttc ttgcacttaa ctttgctata
    12241 tgtactatat tcttttttgg aatacattca tcagtattta gtcctataac tagacctata
    12301 atgattacat ttatagctga aaacatagca gctatgcaag ctggagaaac aatacctcat
    12361 ttctttacag caggagcttc aagtgcattc tttggattta caggatgtgg aattagtata
    12421 ggttgtgtaa ttgcatgtat gttatcaaaa aatgcttcct ataagaagat tggacgtgta
    12481 tcattattcc ctgcattatt tgggataaat gaaccaatat tatttggagc accgataata
    12541 ttaaatccaa taatgtttat accacatgta tttggtggag ctataatagg tacactacca
    12601 atgtttttta tgcactgggg atggttagca aagccagtat ttgaccctcc atatgtaggg
    12661 gtattcttag aaggattttt aactaatgga gattggcatt ctatattagc aaatgcattg
    12721 caattagtat tagcagtttt attatattgg ccattcttta aaataatgga acgtcaacaa
    12781 aataataaaa aacaaaaaga agaaactaag aatatattct ctaaagaaga agaagactta
    12841 ttggatgatt taggattgga tttctaatat tttgttatga ataatacaat agagagatta
    12901 gtatccttaa tctataaaag aggtgttgac gctcttttga ttaaagcaaa aaatactaaa
    12961 agatatatag gagctttatc aggtagtggt gtatatgtgc ttgttactaa ggataaaaat
    13021 tatcaaattc tagatggcag atatattgat gaagcagata aaaaaacgac tggtttcata
    13081 aaaaggattg tatctcaagg ttcttatata ccaactataa ttgagttatt aaaagaatta
    13141 aatataaaaa agttagcaat agaaaaccaa gctatgagta tacaagagta tctttcacta
    13201 aaaaatgaag gttttgaaat caatttaata acaaatgaat tatggaagct aagggctata
    13261 aaatctaaag aagaaattga acttattaaa aaggcttgtg agattacaga tgaagtattt
    13321 gatgaggtta tttctgaaat taaaaaagat atgactgagc tagaagtatc agctctaatt
    13381 cagtatcatg cattaaaaaa aggtgcaagt ggaatgtctt ttgaaacaat agtggtatca
    13441 ggagaaagag gtgcaatgcc acatggaaga cctacaaaca aaaaattgaa agtgaatgaa
    13501 gctataacaa tagattttgg tgttgtttat caagggtatc aatcagacat gactcgtaca
    13561 atatctatag gtaaacctcc taaaattatt aaagagatat atgatgtagt attggaagca
    13621 caattatctg caatagagtc aataaaggaa ggaactaggg caagtgatgt tgacaaagtg
    13681 gctagaaaaa ttatagataa acatggattt ggcgaatatt ttaatcatgg actgggtcat
    13741 ggtataggtc ttggagatgg tgaagttccc actttaaatc caaatagtga agatatatta
    13801 gtggaaggaa tggtaatgtc ttgtgagcca ggtatttata ttccaaatgt agggggagtt
    13861 agaatagaag atgatattgt tataatagat ggaaaaggtg ttccactcaa taagacatcc
    13921 aaagagttta taatattagg agagtaaaat tatgaaatat aattttaata aagtattaaa
    13981 tcgtaaagaa ggaaattgta gaaaatggag caaccatgtg attaaagaaa aattcggctt
    14041 aaatgaagat gcaattccta tggatttagc tgatatcgat tttgagtgtg ctcctgctat
    14101 aaaagaatct atcttaaaaa gagcatcagt aggagattat agttatactt ttataggaga
    14161 tgacttctat gatgctatta taaattggaa taaaagaaga tttgatgtat atatagaaaa
    14221 ggattggata aaattaactt ttggtactgt ttcaaccctt cattatatag ttcaagcata
    14281 tactaaagaa ggagagggtg tattgataaa tacacctgct tatgaccctt ttgcagaggc
    14341 tgtagcaaat aataatagaa agttgtgttg tagctcatta aaattagata acaatagata
    14401 ttatttagat ttagaggata tggaaaatca aatgaaatac gagaatataa gattacttat
    14461 attctgtagt ccacaaaatc catcaggtcg tatatggaca aaagaagaac tatatcaagt
    14521 gtcagagtta tgtttaaagt ataatgtaat tttggtaagt gatgaaattc atagagatat
    14581 aatatttaaa gattatagat ttgtatcttt gtggaatgct catccagaaa tttataaaaa
    14641 tagtataatc tgcgtatctc ctaataaagg cttcaactta ggtggattaa aaacatcata
    14701 tgtattaata agagatgtaa aaattaggga gactttatta gaaaggctaa aaagtaattc
    14761 aataacttct ccaaatgtat ttgcaatacc agcaatagtt gcagcataca atgaaagcga
    14821 agaatggcta gatgctatga ctagttatgt agaggagaat tttgaaatag tttatgattt
    14881 ctttgaaact aatataccaa aagccaaagt gatgaagtca gactcttctt ttttagcctg
    14941 gatagatgta agagaagtat ttagaaatga agaagaatct aaagaatttt ttagacatgc
    15001 aaacttaact atggtagttg gaagttattt tgtgaaagat ggagatggat ttattcgtat
    15061 taatgtgggg tgtcctagag aaacattaaa tgaggctcta aatagaatca aaaaaacgta
    15121 tataagtatg tattgttaaa tcataaaaaa agtatctatg gtttatataa aaacacatta
    15181 tttagttatc aaatattact ggaattttgt attccagtaa tattttttga ttaaggaata
    15241 ttattgagga atattaaata atattatttc atacccttat attaacttat ataaaaatat
    15301 tttattattt tgggaacggg ttagctaacc tttatctagt gtatatttat attgtaagaa
    15361 gcagtaaaaa cttttccctt actaagttta ttaataaact tcttatcttt ataaattttg
    15421 ttagaattta tactatcagc aagaccatac caaggttcta tacataaaaa aggagcagta
    15481 gaattagttt cactataata aggagtccaa ataccaacta gagggaaatc ttccatagat
    15541 atagttacat atttactacc atcattatta tatatagaca cttcatctat gttggtgtat
    15601 atcaaagcat cattcttgaa tacttctgga tttaaatgta agttttttaa ttttccaata
    15661 ggtattatat catctgtaaa agaaccattt aaattgattt tttctacatc atttttactt
    15721 ttaaactcaa ggtagtgttt agaaaaatca ttttgtttgt aaaaaggaag gttgaatgca
    15781 ggatgtccac ctatagaaaa gaatatatct ttagagtcag tattttttac aatccattct
    15841 acctcaatac tattatcatt taatgtatag tttatgatta gctcaaaaga atatggatac
    15901 ttctttaaag tggattcatt atctgttaat ttataagata caaatgtatc tcctttatct
    15961 acaatctcaa agtccatatc tctagcaaac ccatgttgag tcatgctata taaattttct
    16021 tctattattg tttcattatc aaaaagttta cctactatag ggaacaatat aggtgattgt
    16081 ctaccccaat attttttatt accatcccaa agaatgtttt tgtcgtattt tttagaaaat
    16141 attttagtta gttcagcacc aaaactgctt gattcgataa ttaaattttc attttgtaat
    16201 atattcattt aaaatctcct ttattatatt ttatgagtat attatactat aaagtataaa
    16261 gattattaaa ttttatttga tattatattt gaaaggtaga ttttagtata ttttgaaaat
    16321 tttgttttga aaatttggga ttatttaaga aattttgtat tataaataga aggaaataga
    16381 taaattgtat agaataaaat atattaagat aagttaataa tgttaaatgg gaagtgagtt
    16441 tatggaaaaa ccaaatacaa aagttgttaa ctttcaagag tataaagaca gaaaaaacca
    16501 aagagaagta aatagagacg aacttttaaa gcttataaaa aaaattgtga cttcaaaata
    16561 gggagttgtt aaactcccta ttttaatggg tttcataata attaagacat tctgagtcca
    16621 tctatataat ctttgaattg tgagaaatct gattcactac ttaattctat ggtttctgaa
    16681 ccttccgtat aaaaattctt aagatagata gtataattat tatcaacaca atcatgataa
    16741 atacatctat atccatcttc atacaaactt tttaacttag aaaaatcatc cacaatatca
    16801 tctccttaaa gttcttttaa atatattttt acaaaaagca tctaattgta tgcaaattga
    16861 caatgtaaaa taaaggaaat gaacataaaa tgtagaataa tttttatatg tatgtaaaaa
    16921 taaaaagaaa aagttgaaat ttttagaaaa taagagtatt ttttatctaa aaagagagtt
    16981 taaaaaataa aaaaatgttg ggaggataaa aaatgagttt attagaaagt atatcaaaaa
    17041 acatatattc cctagataac tcttctattg aaaaaacaaa gcagagattg gataggctta
    17101 tacatccaac tggaagctta ggaaagatag aagatatttg catgcaattg gcaggaatat
    17161 ttggcaatga aaattttgac acaagtaaaa aggttataat tgcttttgcg ggagaccatg
    17221 gtgtatatga agaaggcgta gcacctgacc ctcaaaatat aacaaaatta cagtttccaa
    17281 atttttcgaa aggtctatgt ggagttggag taataagtaa atttgtaggg gcagatgttg
    17341 tagctgtaga tgtaggaata aactgtgatg aaaaactgga tggggtatta gactacaaga
    17401 taagaaaagg gacatcaaat atggcaaaag gtccagctat gagtaaacaa gaagccatta
    17461 gatgtttaga gataggtatt gaaatagcag agcagtgtat agaaaaagat tataaggtta
    17521 ttggtattgg ggagatgggt atagcaaata ctactccaag tacagcaata atatctgtaa
    17581 tttcagggtg tgacccgtta gaagttactg gtataggtgc aggtcttaag aaagaaagac
    17641 taaagcataa ggctgaagta attagaaagg ctattgaaat taataatcca aatccaactg
    17701 atggagtaga tattttatct aaagtaggag gatttgaaat aggctcaatg gcaggtgtta
    17761 tattaggttg tagtgctaat aggattccag tagtaattga tgggtttatt tcttatgcag
    17821 cagcattaat tgcatataag ataaatccaa aaactagaga atatatgata gcatctcatt
    17881 tatcagcaga atcaggaact aaaagagcat tagacatatt aaaattagac cctctattaa
    17941 atatggatat gagattaggt gagggaagtg gagctgcttt agcatttgat ataatagaag
    18001 cttcaaacta tacttacaaa aatatggcaa cttttgatga aattgacatg ggaagataaa
    18061 tataaaaatt taatatgtag gagtgttttg atgagtaaaa ttattctagt aacaggagga
    18121 gctaggtcag ggaagagtaa ctttgcagaa aaactatgtt ttgacagaaa taataataca
    18181 gcttatatag caacctctat tccatttgat gatgaaatga aagatagagt aaaaaaacat
    18241 caagagaata gacctagaaa ctggaatact tatgaaatat atgaagatat atattccata
    18301 attaaggaga tatataaaga acatgaaact gttatactag attgtgtaac attattagta
    18361 aataatctaa tgtttgaaca caatctaaat atagaagagt ctagtcaaga agaaataaac
    18421 aaattagaac aatacataaa agaacaagtt gtcaaactta ttgaagaaat agaaaaaaca
    18481 aatctatact ttgtatttgt aacgaatgag ttaggtatgg gaattgttcc tgggaataaa
    18541 cttagtagaa tttatgctga tattgtaggt cgtataaatc aatatatagc ttcgaaaagt
    18601 aatgaagttt attttgtagt tagtggcata gctatgaaga taaaggagta gtatgcaatt
    18661 atgaaaagat ttattttaat actacagttt ttgacaagga tacctataaa attaaatgta
    18721 ggatttgatg atgaatttta taagtcaata gtatattttc cacttgtagg ttttgtcata
    18781 ggtatattat cctatttaat aggatggatt tctatgcttt tatttgaacc atttatagct
    18841 tctataataa taactctagc tggtgtctta attactggag gacttcatat agatggatta
    18901 ggagatacat ttgatgcaat atatagttat agggataaag aaaaaatgct tgaaataatg
    18961 aaagattcaa gattaggtac aaattcactt ctagcaatta tgtttgtact tttattaaag
    19021 gttggattcg tttacgatat aataagtaat aattcattgt ggattataat ttttatgcca
    19081 atgattgcaa ggttaggagt aatgttattg acatataaaa ccgtgacacc aagagaaaaa
    19141 ggaatgggaa atttatttat aggaaaatta actacaagta tgttaataac tgctataata
    19201 tacacattat tgatagttgc tcttattact aaatttatat ttttattacc taatatagtg
    19261 ttgattaaag tattaggttc gattatagtg gtttttgtat ttataatatt attcaaaaaa
    19321 catatttata aaaaaattga cggagtaaca ggagatatat taggctgtgg aatagaactt
    19381 tcagagcttg tatatttaat ttacatatat ttgttaattt ttatgttttt ttaaagtaaa
    19441 aagtggtgat aatatgataa gattaatatt aataagacat gcactgacaa atgataataa
    19501 aaaaggaaga ttatcaggcc atataaatag ttgtattagt gaagagggca aactacaaat
    19561 aaataaaatt accagatatc tgagtaatga aaacatagat aaggtttata caacaccatc
    19621 tacacgtact aaagatacag tagaaaaaat atcaaaattg aaattattag aaatagaaga
    19681 aaaagaagct ttaagagaaa ttagttttgg agactttgaa ggaagaactt ttgaagaaat
    19741 taaaatcaaa tatccaaatg agtttgaaaa aatgataaaa gaaggtaaca actatagata
    19801 tccaaatgga gaaagtttga tagactctta taaaagagtg gcaaaagaaa ttgataatat
    19861 aattttagaa aatgatagta atttagatac aaagacaata cttatatgtt ctcatgcagg
    19921 aacaataaga aatataataa cacatttgat ttctggtagt tataagtatc actggaactt
    19981 taaaattgat aatgcatcta ttacagtttt agaaattgat ggtggatttg ctgtaataga
    20041 taaaatgaat tttacagact tcatataatt taatcaaaac caaacattac aatctgtgtt
    20101 tgtaatatat ctgtaaaatt agcaatgaaa atagaatatt agattaaaat taggttctta
    20161 attagatgtt aaaagggaaa aaggttagat gcctttgcag cccccgctac tgtgaaacca
    20221 acgaaactat aaataccact gtcagtttga tgggaaggtt atagaagtag gatgaagtta
    20281 agccaggata cctgcctaat ttaatttaaa acaagaggtc ttcggggtga aagattttta
    20341 attaatatat ataaaagtcc tatctttaga agtattagga ctttttttaa tttgtttttt
    20401 agtaaatttt aacaaggagg gatggaaagt ggggaaaaaa ataatgctac aaggaacagc
    20461 ttcaaatgta ggtaaaagtg tcttagtagc aggtttgtgt agaatattta agcaagatgg
    20521 ttatactgtt gctcctttta agtcacaaaa tatggcttta aattctttta taactaaaga
    20581 aggattagaa atgggaagag cacaagtatt tcaagcagag gctgcgaaaa tagagccaat
    20641 agctgatatg aatccagttt tattaaaacc ttctgggaat aataaaagtc aagttattgt
    20701 aagaggtaaa gttgtaggag aaatgccttc ttctaagtat catgattata aattggagtt
    20761 agtaggtgtg ttgaaggaaa catttaatag cttaaattca aggtatgata ttgtagttat
    20821 ggaaggggca ggaagtaatg cagagataaa cttaaaagat agagatatct ctaatatggg
    20881 tatggcagaa atagctgatg cacctgtaat aatagtcgga gatattgata gaggaggcgt
    20941 atttgcctca ttagcaggaa caatgctttt attaaatgaa gatgagaaaa gaagagtaaa
    21001 aggtgtaata atcaataaat tcagaggaaa aaaagagctt ttacaagatg gtgtaaagat
    21061 gctagaagac atcataaaag tacctgttat aggagtagta ccttatacag atataaaaat
    21121 agaagatgaa gacagtgtaa ctacgagatt taagaaaaaa atgaataaaa gtgatataca
    21181 catagaaata attagaaccc cacatatgtc aaattttaca gattttaata tatttgagac
    21241 acaagaagat gtaagtatta gatatgtaga ctatggagaa tctttaggaa atccagatat
    21301 attaataata cctggaacta aaagtactat agacgattta acatatataa gaaaaagtgg
    21361 tcttgaatcg caaatcaaaa atttacatag tcaaggtaaa ttgatatttg ggatatgtgg
    21421 tggataccaa atgttaggta aaaaattaaa agacccttat catgttgaaa gtgaaattga
    21481 agaagttgat ggaataggtc ttttagatac agaaacaacg tttgagaaag aaaagactac
    21541 aacacaagta gaggctacta ttgttgaatg tatcagtgaa tacatgaata accttaaggg
    21601 aaaaaaagta aaaggttatg aaattcatat gggcattaca aagcgaggta atgatgtaag
    21661 aagtttagat ttaataacta aaaaacttga taaagaagtg aattatactg aaggaagtgt
    21721 aaataaagag gggaatgtaa ttgggactta tcttcatgga atatttgatg aaataagctt
    21781 tacaagagca attttaaaca atataagaaa gaaaaaaggt ttaggagaat tagaaagcaa
    21841 agtaaactct tttaatgaat ttaaggataa agagtatgat aagttggctg attttttaag
    21901 agaacattta gatatagaga aaatatatga gattatgaaa taatgatgac ctttatttat
    21961 aatttaggta ggaggtgtat tatgaaaaaa attttaattg ctggtactaa tagtggagta
    22021 ggtaaaacaa caatatcatt aggaataatg caagctttgg ttaagagaaa tatgaaagta
    22081 cagccatata aagtagggcc agactatata gacccttcat atcacacttt tataactgga
    22141 agacattcta gaaatttaga ttcttatatg ttagatgatg aaaaaataaa gtatatagta
    22201 aataagtcct caaaagatgc agatatttca gtaatagaag gtgttatggg cttatatgat
    22261 ggttttggaa tagatttaga taattgtaca agttcacata cttcaaaggt attaaagtca
    22321 cctgttatat tagttataaa tggtaaatct atggcagcat ctagtgctgc tatggtactt
    22381 ggatataagg aattagataa agatgtaaat ataaagggtg ttatagtaaa taatgtaaag
    22441 actaatagcc attatcaaat aattaagagt tctatagaaa aatattgtaa tgttgaagta
    22501 ttggggtatt ttcctccaaa taacaaattc tctttagaat ctcgacatct aggattagtt
    22561 cctagtgtag aaatgaaatc actaagggaa aaattttata ccttagcaga tgaaattgaa
    22621 cactatatag atattgacag aataattgaa atatcagaaa gcgatgaatt tgagagtgat
    22681 tttgattttc aaactttgat agaaaataat aaaataaaag aacatgttaa taataaatca
    22741 atagctatag catatgataa agcattcaat ttttattata gagaaaatat agagctttta
    22801 gaggaacttg gtttagaaat aaactatttt agccctcttg aagatgcatc agtgccaaat
    22861 gcagattata tttatattgg aggaggtttt ccagaaatat ttggaaaaga attagaagca
    22921 aatgagtcaa tgagaacttc catattagaa gcacataaca ataatatacc tatttatgca
    22981 gaatgtggag gactgatgta cctaggtgag aaactattga atcaagaaga acaagaattt
    23041 aatatggttg gaatatttag tggaattagt aagatgacat cttctttaaa gagatttggg
    23101 tactgtattg gtgtagccaa ggaaaatact cttttatcta aaaaagggga atctattaaa
    23161 gggcatgagt ttcatcattc aatatttgaa agtgatgaaa aatgtgtata ttcaatgaga
    23221 aaagaaagag atggaaatat agtagaagag tgggatggtg gttatagtaa aggaaacact
    23281 ttggctacat atcttcatac tcatttttat aataacttaa attgtataga aaattttttg
    23341 aaaaaaggaa atgaataaat gagtatttta tctatttata taggatatgt gacagactta
    23401 attgtaggag acccatattc ttttcctcat ccagtgagat ttattggtaa acttataaat
    23461 tttactcaag gtataataag aaaggtctct aaaaatgata ggcagttaaa atttggggga
    23521 tttatattat ggtttataac cgttggaata acatatttaa caacttatgc tatagtgaag
    23581 ctatttagtt ttaatatatt attgagtatt gtagtgaata gttttataat ttatacaaca
    23641 ctagccacaa aatgtttaaa agacgaagca ttaaaaattt ataatgtatt aaaaaccgaa
    23701 gatatagaaa aatctaggat tcagctatct tatatagtag gtagggatac tactaattta
    23761 agtgaacctg aaataataag agcaactgta gaaactgttg cagaaaatac tgtagatggt
    23821 ataattgcgc ctatgtttta tgcatttatt ggaggagcac cacttgctat ggcctataaa
    23881 gctataaata cattagactc aacagttgga tataaaaata aaaagtataa agatattggt
    23941 tttgcatctg ctaagattga tgatatagcc aattatatac cagctagaat atctgttatt
    24001 cttatgacaa ttggaagttt ctttttaaat tataactata ggaactgttt taaaatctct
    24061 attagagata gaaagaatca taaaagtcca aattgtgctt tttcagaagg cgcagtatct
    24121 ggtgctctag gaatacaact aggaggtacc aacgtttatt ttggggaaaa agtatataag
    24181 ccaacaatag gggataagct tagggagata gataaagaag atataattaa aactaataaa
    24241 attatgtatg tatcttcatt tgtatctatg ttggtattta cactaataca tgtgttatgt
    24301 aggatgattt taattaactt aattatataa attattgttt gctaacttaa gggggacata
    24361 gatgaaggat ttagggcatg gtgccaatgt aggtgaaatg gcaagattat atgggaaaaa
    24421 cccaaaagaa ataattgatt ttagttcaaa cataaatcca aatgtattac caaatttaga
    24481 gagatacatt ttaaaaggat tagaagagtg taggaattat ccagatataa attatacaaa
    24541 cttgagagaa aatatatcaa aatatatagg tataaatcca gactttataa tacctggaaa
    24601 tggtgcaaca gaagtgattt atttgcttat gaagagtgtt aaaaaaaaat tggctataat
    24661 aaatccgact ttttcagagt atagaagaag tgctgagtta aataatttag atattataga
    24721 tttagagcta gatttagaaa ataactttaa acttaatata gatataataa aagaaaatat
    24781 aaaaagattt gatagtttat ttatatgtaa tcctaataat cctagtggta atgtccaaga
    24841 tttaaaggaa cttgttcatt tactaggtaa acataataag gtactaataa ttgatgaaac
    24901 tttcatggaa tttgttgaag atgaaagtaa atacagtttg gttaaatata tagaatcaaa
    24961 taaaaatata tttataatta aagctgtgac taagtttttt ggtatgcctg gtttaaggct
    25021 aggatatggt cttacaagca acactgaaat tatgaacaaa atttatgaac acaaagagcc
    25081 atggactatt aattcttttg cagatatact atccaatttt atttttgaag ataaagagta
    25141 tattaaaaat agtaaagaat attacataga agaaagaaaa tatatgttac aagagttgag
    25201 aaacataaga aatataaagg tctatgatac agatgctaat tttattttga taagagcata
    25261 taaaaaaaca actaaagaat tgaaaaaaga tttgcttaag caaggaaaca tattagttag
    25321 agatgcgtct aattttatag gattagatga tagttttata agagtggcta taaaatctca
    25381 tgaagataac aaaattctta tagaaaatat gaaaaattta ttgggtgatt aaaatgaaat
    25441 cttatggaat atgcccagca tcttgtggag aatttgtaca aggtataatt gatgatgaag
    25501 aatatttatg ttcatatgca atagatatgt attctgaagt gtatattgaa gaaaaattag
    25561 tagatataaa tttagggaga tataagtcaa ggttagcaat tgaaaaggta tttgaaaaat
    25621 ttaatttacc taaaaaatat actaaaaata tttctttaaa tataaatagt aaaatacctg
    25681 ttggaaaagg aatggcaagt tcaactgctg atataggagc tacaataaag gcaacattat
    25741 cattgataga taaagattta agtagtgagg agatttctaa attagcagca gaaatagaac
    25801 caacagattc tatatttata gataaaaata gtatatttaa tcctctaaat ggaactgtta
    25861 taaaatacct aggaaatctg accaatgcga aagttataat acttgaacca aacaaagtac
    25921 tagatactat gaaaattaga ttgaggcaag attataataa attaaaagta gaaaataaag
    25981 aagtaataaa aaaatcattt gctcttttag aagaaggatt gaaaaaaaat aatttatctc
    26041 tagttggaga ggcttgtact ttgagtagct tagcaaatga gaatatagaa aaaaaagagt
    26101 atttaaatga aataataaaa atatcaaaaa aatatggagc atatggagta aatattgctc
    26161 acagtggaac tgtagtaggt attttaattg ataagtctat gaatgataaa aagatgatag
    26221 ataccttatg tgaatctaac ataaattctg tctataataa aatttataca caaaacataa
    26281 ttaatggagg aattaagggg gaaatagaat ggaatacata aagaatccta tgaaaataga
    26341 agaaaaaagt tttgaattga tacaagaaat aatagacgaa attagaccag attataaatt
    26401 taagaataat attgaagaaa aaataataaa aagagctata catactactg ctgattttga
    26461 ttacttagat atattaaaaa tatcagaaga agcagttgat agtataatag atgcattaaa
    26521 aaataatgca agtatttata ctgatacaaa tatggctctt agtggtataa ataaaagaaa
    26581 gttagaatca ttaggatgta agtataaatg tttagtggca gatgatgaaa ctgtaaaatt
    26641 agctaaagaa aaaggaatta ctcgttctat ggcagcagta gaaattgcag ctaaagaaga
    26701 aggaagaaaa atattcgttt taggtaatgc tccaacagct ttatataaag ttatggagat
    26761 gaaatcagaa ggtagattag atttagatgc agttatagga gttcctgtag gttttgtagg
    26821 agcacaagaa tcaaaagatg aagttgaaaa aacagatata ccatatataa tttctaaagg
    26881 tagaaaaggt ggcagtaatt tagcagcagc aatagtaaat gctatattat atactatgta
    26941 ggtacctata tggaagaata tgtatatata gatggaaaaa aatatagaag aggatatact
    27001 acaggttcat gtgcaacagg tgcatctaag gctgctgtat atatgttgat tacaaaaaat
    27061 agaatcaata ctataaatat agatactcct aaggggatac cattactact aaaagttgat
    27121 aatataaata tttctgatac atttgtggaa tgttccataa aaaaagatgg tggagatgat
    27181 atagatgcaa ctcataccat ggatatttat gcaagagctg aaattgtagc taaaaatgat
    27241 aagaacaaag ggtatcttac tctaaaggat atagatagtt taagcaccaa tagtgagtgt
    27301 aaaagtgagc tctataagtt tattagggtt tatggcggaa ctggtattgg tgtggttacg
    27361 aaaaaagggc ttagtgtgga tgttggtaaa cctgctataa atccgactcc acttaaaatg
    27421 ataaaccatg aaataagaaa gcttatagga gataattttg aatctatact tggaaatgat
    27481 aaagttttaa aaataacaat ctttgctcca caaggagaaa ctgtagcaaa aaaaacattt
    27541 aatccaagat taggtatagt tggaggaata tctataatag gtacaactgg gattgttgaa
    27601 cctatgagtg atgagggttg gaagaagtct ctttctatag aacttcagat gaaaaaagaa
    27661 caaggcttag ataaaataat attggttcca ggaaatcatg gagaacagtt tataagagaa
    27721 aaattaaact tagatattaa gtatgtagtt agggtaagta attttatagg ctatatgatt
    27781 aaagaagctc aaagaatagg atataaaaaa atcttaatgg caggtcatat aggtaaattt
    27841 ataaaagtat ctgctggtat ttttaatact catagtaagg tagcagatgc tagaagtgag
    27901 atattagtgg caaacttagc tttaatggga gctagatacg aatttttaaa taaaataaat
    27961 caatgcgtaa ctactgaaga agctgtagag ctaataaata atagtgaata tagagaagta
    28021 tataatatat taagtaataa atgtaaggag agagtaaagc aatacttgaa tgaagattca
    28081 gatgatattg atgtggaagt aatcatattt tcaatggata agtctttatt aggtaaatcg
    28141 gataatacag atgatttagt ggaggtcttt atatgataaa cataataggt ctaggacctg
    28201 gtaacttaga ctatataaca aaaaaaggtg aaaatttaat ttccacttct gatgtattaa
    28261 ttggtggtaa aagaaatcta gagtctataa aaaattttga aggagaaaaa atagttctgg
    28321 attctaattt aagagaaatt atagagtaca taaataacaa taaagaaaag caaatatcaa
    28381 taatagcatc tggggaccca ttaatatatg ggataggtag atatctatct aaaaatattg
    28441 ataataagat gttaaacgtg gtttctggga ttagttcatt acagtacata ttttcaaaaa
    28501 tatatgtaga tatgaatgat gtatatatta caagtagtca tggcaaaata ccagattttg
    28561 attacatatt atcacataaa aaagtatgta tggttacaga ttcaaagata ggaccaaaac
    28621 aaataagtag agaaataata gatagaaatc taaataaaat tattgttgta ggagaaaatc
    28681 tgtcatatga caatgaaaaa ataacaatag cgaaaccaga agagataata agaatggaca
    28741 attttgatat gaatgttgtg gtgattttag atgaggaata gtgaatttat aacaggtaaa
    28801 gttccaatta ctaaggaaga ggttagagca atatcaataa gtaagttaaa tttagtaaat
    28861 gctaaaaacc tcatagacat aggggctggt acaggaagtg taagtgttga agctgcatat
    28921 aattatccta atttaaaggt tatatctata gagaaaaatg atgacgctat agagcttata
    28981 gagaaaaata taaaaaaatt caacttaaaa aatatagaag tgataaaagg atatgctcca
    29041 attaatctag ggttaaatgt taaagttgag tctatttttc ttgggggaac aggaaataat
    29101 ctggaagaaa taatagaatg gtctaaaaaa aatctcgtta caggaggaag acttgtagct
    29161 aattttataa taatagatac atttaatcaa actttaaaac tgcttaaaaa gcatggattt
    29221 aaagaaatag atgtatgtgt tttgaatgtt tctaaactag agaaactagg aaaaggtgaa
    29281 tattttaaac cactaaatcc tatatatata atatcttgtg aaaaagggga aaatgatgat
    29341 gaataaagta cattttgtag gagcaggacc tggagataaa gagctgataa cattaaaagg
    29401 atacaaatta ttaagtaatg cagatgtagt gatatatgca ggttcacttg ttaatcctga
    29461 acttttggaa tactgtaaag aagattgcca aatacataat agtgcacata tggatttaca
    29521 agagataata gatgttatga gagaaggtat agaaaataat aaatctgttg taagactgca
    29581 aacaggtgat ttttctatat atggttcaat tagagaacaa gtggaagatt taaataaatt
    29641 gaatatagat tatgactgta ctcctggagt aagttctttt ttaggggcag catcatcttt
    29701 aggggttgaa tatacagttc cagaaatttc tcaaagtgta attataacaa gaatggaagg
    29761 cagaactccg gttccagaga aagaatcaat acaatcatat gctaagcatc agacatctat
    29821 ggtaatattt ttatctgttc aagaaattga gaaagttgtg tctaaattac tggaaggtgg
    29881 atatccaaaa gatactccta tagcagttat atacaaagca acttgggcag atgaaaaaat
    29941 agttaaagga actttaagtg atatagctgt aaaagttaaa gaaaacaaca taaataagac
    30001 tgctttaata atggttggga gatttttagg agaagagtat aataattcaa agttatatga
    30061 taaggatttc aaacatgaat atagagggta atattgctat aatctgtatt acagaaaatg
    30121 gaaaaaattt agctgtaaag ataaattctc tagtaaataa ctgtgttata tatcaagtaa
    30181 aaaataaaaa aagtaattta gttgttgaag aaacatgtgt acatacagtt caaaagaagt
    30241 taagtgattt tgtaggagaa atatttagca aatttgatta cataatattt ataatggcta
    30301 caggtatagt tgtacgaagt atagcaccat acataataag taagtttagt gaccctgcaa
    30361 ttttggtaat ggatgaaaaa ggcaaaaacg taataagttt attgagtggt catattggag
    30421 gggcaaacag cttgacacag tacataagta gtcttattga tgctaatcca gtaataacaa
    30481 cagctactga tataaatcaa aaagcttcct tagatatgat agcaaaaaaa ctaaatgcac
    30541 atattgataa ttttagagaa agtgtaaaag aagtaaattc tatgctagtg aataataaat
    30601 gtgttggatt atatgttgat gaaggatatc aagttgatac taggggattt aaacttatag
    30661 aaagtaagga tgagttaaga gatagctttt caaacacata tatagaaaaa ttagttgtag
    30721 taagcaataa aataaattgt attgaagata ttgagaattt aaacttagat aataaatttg
    30781 aacattgcta tagtactaaa aaaataataa aggtaattcc aagagatata gtgataggaa
    30841 ttggctgtag aagaaacaca gatagtgagc tgatgtataa ttcacttgaa gagtttctta
    30901 ataaacaaaa tatagatatt agagcaataa acacagttgg aagtatagaa ctgaaaaaag
    30961 acgaaaaagc aataattgaa ttatcaaaaa tactaaaagt gccatttaaa acattttcaa
    31021 tagatgaaat atctaaggtt gataatcttt ttgataaatc tgattttgtt aaaaaaaatg
    31081 tgggcgtgta ttcagtagca gaacctatag catatctttt gagcaaaggt aatttgttag
    31141 ttgaaaaaca taaatataaa ggaataactt tttcagtggg gagaataaaa atatgatata
    31201 cgttgtagga attggaccag gaagtaaaga tacaatgact ttagaagcaa taaaagcaat
    31261 agaagattct gaggctattg ttggatataa gacttatata aaactaatag aagaatttat
    31321 acaaggtaaa gaaataatcc aaaatggtat gaggcaagaa gttgatagat gtaaacaagc
    31381 agtagaggaa gcgaaaaaag gaaaaaaagt agcagttgta agcagtggtg atgctggaat
    31441 atatgggatg gcaggtctca ttttagaatt aatatctaaa gaagatgaag atataaaagt
    31501 aaaggtaatt ccaggtgtta ctgcaagtat tggtgcagca gctatacttg gagctcctat
    31561 tatgcatgat ttctgtcata taagtttgag tgatttaatg actccgtggg aagtaattga
    31621 aaaaagattg agattggctg ctgaagccga ttttgtaatt tgtttgtata atccaagaag
    31681 taagggaaga agtgaacatc taagcaaagc atttaaaata atgggtgagt ttaaaggtgg
    31741 agatacacct gttggagtgg taaaagatgt aggtagagaa aaagaagaaa agtttgtatg
    31801 tacttttgaa aatatggact ttgaaaaagt cgatatgact acaatggtta taataggaaa
    31861 taagtctacc tatattaatg gtgaattgat gataactcca agaggttata cagtatgatt
    31921 ttaattttag gaggaacttc agatagttta tctatatgtg ataagataaa tgaactgaaa
    31981 aatcaaccat atatcctttc agttactaca gattatggaa gggaacttgc acaacaacat
    32041 gcagagaatg taattttagg taagcttgga aaagaagata tgctaaaatt tataaaagat
    32101 aataatatag taaaaataat agatgccact catccttatg cagttgaagt atccaaaact
    32161 gctattactt gtgcaaaatt attgaatata gattatataa ggtttgagag aaaatcttta
    32221 attgaagaaa tagattatga taataaattt atagtagata caattgaaga agcctgtgaa
    32281 atagcaaata aaatagggac aaatatattc ataggaacag gaagtaaaaa tttgaacaga
    32341 tttatagagg aaataagtga taaaaattta gttgttagag ttcttccaac gagtgaagtc
    32401 atattaagtt gtgaaaaatt aggtttaagt gcagataata tagtagctat gaaaggtcca
    32461 tttagccagt atataaatga agaaacatat aaacattaca atatagattt agtcataaca
    32521 aaagaaagtg gaatagctgg tgggttctta gagaaggtaa atgcatgtaa aactttcaat
    32581 ataccagtaa taattataaa aagagaatcg attaactacg aaaatgtatt taatgacata
    32641 aataaaatta aagacatact tgtgtaattt ttaggaggag aatatatgaa gaaagcctta
    32701 ttagtagtga gttttggtac aagctatcat gaaacgagag aaaagacaat agatatatgt
    32761 gaagataaaa taaaaaattc gttaaaaagc catgattttt ttagagctta tacatcaaat
    32821 atgataataa ataaaataaa aaaaagggat ggaatagaaa tagataatcc aatacaggct
    32881 ttagataaaa tatatgaaca aggatatgat gaagtaataa tccaaacact tcatattata
    32941 tgtggcgaag aatttaacaa attaaaagaa caagtagatg gatattcttc taaattcaaa
    33001 aagattgtat taggaagacc tttgcttaca catattgaag attatcagga agctgtagag
    33061 gcaattaagc atcaaattcc tcatatggaa agtaatgaag cagtagtatt tatgggacat
    33121 ggaacacttc atgaatcaca ttcagcgtat ccagcattgg aatacatgct tagggataat
    33181 ggaataaatg cttatgttgg tacagttgaa gggtatccag aaatagaaca tgtaataaga
    33241 agattaaaag aaggaaatat aaaaactgta aatttgatgc catttatgtt agttgcagga
    33301 gaccatgcta taaatgatat ggcaggagat gaagaagatt cttggaaaac aatattagaa
    33361 gaagatggat ttgacgtaag agttcattta aaaggactag gagaaaattc ttatatacaa
    33421 gataaatttg ttcgtcatgc tgtaaaatgt gcagagaatg ctaagttcta tggtatagga
    33481 gcagggccag gagatggttc tttacttacg ataaaagcgg ttaatacttt aaagaaactg
    33541 gatattctat acactccaga atcaaaaaag ggtggagata gtctagcttt atcaatagtt
    33601 agtgaatatt tacctgaatc agtggaaata aagtctaggc atttcccaat gagttttgat
    33661 gggaatgaaa aaagtttagc ttgggacaat gtagcacaag aaattatatc agatgttaat
    33721 gatggtaaaa atgtaggatt tgttacatta ggagacccta tgatttatag tacatatgta
    33781 tatataatga aaagaatatt aggagaggta gaagtcgaaa ctataccagg aatttcatca
    33841 ttttccaata tagcatctaa tcagaatttt ccattagtca tggataaaga agctttagtg
    33901 gtaattcctt gtactatgga agatgataag atagagtatg ctttgcaaaa ttataattca
    33961 atagtattga tgaaggtata taaaaatttt aaagaaataa taaaaaaatt agaaaagtat
    34021 gatttaatag aacatgctat tttagtaagt aattcttccc aagaaagcga aaatgtgttt
    34081 acagatttaa aagaagcgca ccttgaagat aagatatctt atttttctac tatactagta
    34141 aataaagata ataaaataaa ataggtgaaa gcaatattta aaggagactt aatatgaata
    34201 tagtggttgg aactaggggt agtactctag cgcttataca aacagagtgg gtaataaatg
    34261 aattaaaaaa gaagtatcca gaaattagtt ttgagattaa aatcataaag acaaaaggag
    34321 atttaattca aaatgtttca ctggataaaa taggtgataa aggattgttt gtcaaagaaa
    34381 tagagcaaca attattagat ggaaaaatag acatagcagt acatagtatg aaagatatgc
    34441 cttcttattt agcagatgga ctaaaatttg ctcatacgcc taagagagaa gacccaagag
    34501 atgttctaat acttagagaa ggatataaaa atttagatga tttgcctcat ggagcagtaa
    34561 taggaacagg aagtaaaaga aggaagtttc aattattgaa acaaagacct gatttaaata
    34621 tagtacaagt tagaggtaat gtggaaacta ggatacgaaa aataaaagat gaaaacatgc
    34681 atggtattgt gttggcagca tcaggaataa ttagagctaa tttgcaagat aaaataagtt
    34741 cttatttacc tgttgatgtt gttattccag cacctgccca aggagcttta gctatagaaa
    34801 ttagaagcaa tgatagtacg atagagggaa tagtaaattc actgaaggat gagaatacag
    34861 aaatccaaat attggctgaa agaggttttt tagatggtgt aaatggaagt tgtcatattc
    34921 caatggcagc ttattgtgaa ataatccaag ataaaataca tcttactggc ttatatggag
    34981 attcagaagg aaaaaaagta gtaatcaagt ctatagatgg agatatttct tctcctagag
    35041 agttaggttt aaagttagct aaacttgtat tgaaggagta tgagaattat gaagggtaag
    35101 gtttacttag taggggcagg accaggtgat tataaactca tgactttaaa aggtttagag
    35161 tgtataagaa aatcggatgt aatagtatat gatagattag caaatagtag ttatttaaga
    35221 gaagctaagc ctgattgtga acttatatat gtaggcaagg catcaagtaa tcatattttg
    35281 ccacaagaag atataaatag aattatagca gaaaaagcta aagaaggaaa aattgtaact
    35341 cgtcttaaag gaggagaccc ttatgtattt ggcagagggg gagaagaagc agagacttta
    35401 gtagatgaag atatagaatt tgaagtagtt ccaggtataa cttctgctat aggaggttta
    35461 tgttatgcgg gtattcctat aacacataga gaccatgctt cgtcatttca tgtaataaca
    35521 ggtcatttga agggtgatga tagtggagaa ttaaactgga atgctcttgc aaataacaaa
    35581 ggtactcttg tgtttttgat gggaatttca aacctagaga aaataagtga aaacttaatg
    35641 aaagaaggaa aagataagga tacacctgtt gctcttataa gttgggcaac tagatataat
    35701 caaagagttg ttacatctac acttgagaat gtttatgaaa ctgctattaa agaagaagta
    35761 aaaccgccaa ctcttatagt agttgggagt gttgtaggac ttagagaaaa gttgaacttc
    35821 tttgaaagta agcctttatt tggaaaaagt attgctgtaa ctaggtctag aaatcaaaat
    35881 agtgtattgg tagaaaaaat aatggattta ggtggaaatc ctatagaaat acctactatt
    35941 aaggtagaaa aaatacaaaa taatattaac ttagaaaatg aaataaaaaa tataaataag
    36001 tataattatt taatactaac tagtaaaaat gccgtagaaa tcttctttga aaagatatat
    36061 gaaatgaatt ttgatttaag gatattatct aatttaaagg tatgtgctat aggttctgct
    36121 acatcaaatg agttgaaaaa aagaggaatt atagcggata tagtaccaaa aaaatttgta
    36181 gcagagtcac tgtatgaaga gttagctcct attttaaatg ataacgataa tatacttata
    36241 cctagagcag aaaatgctag agattatctg gttgacaaac ttaaggctat ttgtgaagta
    36301 acagaagtac atatatatag aacagtaata gatgaggata aaaaaggtga gatattagat
    36361 attttaaatt ctaatgatat agattatata acatttacta gttcctcaac agtaaataat
    36421 cttgttgaaa ttataggaaa agaaaatatt aaaatattag aaaaaataaa aacactatct
    36481 ataggtccta taactacaga gacaataaat agtttgggaa taaaattgta caaagaatct
    36541 gctacatcta ctatagattc gttagtagat ttaattataa aaaattaatt ttggaggctt
    36601 gaatatgtta agaagaccaa gaagactaag agcaagtaaa gcaatcagaa atttggtaag
    36661 agaaactaag gtgaatgtag aagatttaat atatccactg tttgtagtag agggggaaaa
    36721 tataaaagaa gaaatcaatt ctttaccaga tgtatatcat ttatcaatag acatgctaga
    36781 agacgaaata aaagaaataa gtgagttggg aattgaacat ataatgttat ttggtgttcc
    36841 agatgaaaaa gatgagtgtg cttcacaagc ttttaatgat aatggaatag ttcaaaaggc
    36901 aattagaaag gtaaaagaaa taaattcaga tataaatgta ataacagatg tctgtatgtg
    36961 ccaatataca agtcatggac attgtgggat tttaactgat actggttatg ttgataatga
    37021 taaatcattg gagtatttgg ctaaaatatc tgtaagccat gctaaagcag gagctgatat
    37081 ggttgctcca tctgatatga tggatggaag aatacaagca ataagagaag ctttagatga
    37141 aaatggatta gaaaatgttg gaatcatggc ttatagtgtt aagtatgctt caaattatta
    37201 tggacctttt agagaggcag ctcattcagc accatctttt ggagatagaa aaacatatca
    37261 aatggaccca gcaaatagca atgaagctat aatagagact gaacttgata tattggaagg
    37321 tgcagatata cttatggtta aacctgcatt atcatattta gatattataa gaagagttaa
    37381 agataatttt gacttacctc tagcagctta taatgtaagt ggagaatact ctatgcttaa
    37441 gtttgctgtg aaggaaggtt tattaaatga agatgtaatt cttgaatcaa ttacatctat
    37501 aaaaagagca ggagcagata taataataac ttattttgct aaagacattg ctaaactgtt
    37561 gaaaaaataa attctagtag tataaagaat atcaaaaagt ataggaattg taattaacta
    37621 ttatacagta gttttgttta gacatttatt gaagaataat agaaactaat ttacaatttc
    37681 tatactttat ttatgtaact aaataaaatt tggaggtaga agatgctata tcctattaat
    37741 ttaaaattag atgagttaga tgtagttata attggtggtg gagaagttgc atataggaaa
    37801 tgtaaaaatt ttttagagtt taacaaaaat gttactatag tttctaaaca aattttaaat
    37861 aaattttatg atttaaaagg aaatataaaa ataataaaag atgattataa agaaatatat
    37921 ataaaagatg cttctgtaat aattgctgcc acaaataata gagagttaaa tatggaaata
    37981 ggattatatt gtagagcaaa aaataagcta gtgaatgtag ttgataatat agaaatatcg
    38041 aactttactg ttccatcata tataaaaaga ggagatttac ttataagtgt gtctactggg
    38101 ggcaagagtc cttcattatc atcaaagata aaaaaagaaa ttgaagagag atatactgaa
    38161 gattatgagg agtatttaaa tgtattagga gatataagaa aaaaggttat aaaaaaatac
    38221 gaagataaaa gtaaaagaaa agatgtgctt aatatgttgg taacacttga cctagaagaa
    38281 cttaagaagt ttgatatata aaaaataaaa taaaaaatgt taaaaaggtg ttgacggatt
    38341 atttttaaga tgatatagt
//
LOCUS       DAMJWO010000036        38328 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.037, whole genome shotgun sequence.
ACCESSION   DAMJWO010000036 DAMJWO010000000
VERSION     DAMJWO010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38328
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.037"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            40..246
                     /locus_tag="PC366_001847"
     CDS             40..246
                     /locus_tag="PC366_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577376.1"
                     /translation="MSKYSSLWEYVKKNNSQSFKLTFEEIKDIAGIEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFNKID"
     gene            complement(557..1300)
                     /locus_tag="PC366_001848"
     CDS             complement(557..1300)
                     /locus_tag="PC366_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HDF2577377.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHRWYFHNIQNIPRIINNIIILRGCEANILDIKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHDNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNYPKKLINHFHQKGKLLDVDYTNI"
     gene            1466..4033
                     /locus_tag="PC366_001849"
     CDS             1466..4033
                     /locus_tag="PC366_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2577378.1"
                     /translation="MTQKKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFDNINSINEYS
                     ENDSIKDEYILESIKKENNIFNLVGCDGSLRSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLTIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGVLFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESVRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKDFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDGDIQKYSYNLMNTFIYNNSNQTAYNNIVNDSIATTVKYILQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANKIDKGKGILILTDMGSILTFAKVIRDATGKEVKAVDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEVTYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRNKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            4263..4667
                     /locus_tag="PC366_001850"
     CDS             4263..4667
                     /locus_tag="PC366_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2577379.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            4691..5188
                     /locus_tag="PC366_001851"
     CDS             4691..5188
                     /locus_tag="PC366_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2577380.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEVELNQNINRY
                     KGEFI"
     gene            5191..5592
                     /locus_tag="PC366_001852"
     CDS             5191..5592
                     /locus_tag="PC366_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HDF2577381.1"
                     /translation="MNKYKVIILCHGTWGKVLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKEVEEVVDKEDVKIIISDLYGGSTSSVAIAVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            5610..6098
                     /locus_tag="PC366_001853"
     CDS             5610..6098
                     /locus_tag="PC366_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2577382.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGNEDVEQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            6125..6880
                     /locus_tag="PC366_001854"
     CDS             6125..6880
                     /locus_tag="PC366_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2577383.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLDVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            6880..7743
                     /locus_tag="PC366_001855"
     CDS             6880..7743
                     /locus_tag="PC366_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2577384.1"
                     /translation="MQEIKNKEVKNGQGPTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKKKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIMFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLGVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            7790..8269
                     /locus_tag="PC366_001856"
     CDS             7790..8269
                     /locus_tag="PC366_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HDF2577385.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGANPDDIC
                     KEAIYGFGKMRGQKYNVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQGVKLDFAQKCAHDDEVCELVFTKK"
     gene            8334..9641
                     /locus_tag="PC366_001857"
     CDS             8334..9641
                     /locus_tag="PC366_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2577386.1"
                     /translation="MDISRSVDNSLNRTIEFLKELIKIDSQQGEPISQCPFGIGPKKS
                     LDKTLDYCASLGFSVKNIDNYIGYAEIGEGEELIGIPMHLDIVPPGEGWSVDPFSGAV
                     IDNIIYGRGVIDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETDMKCIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIIVRGGTKENVVPSHC
                     TAKIINGIISELTTKGVAVHASNPEKGENAISKMVIKIVEDNMDFQHREDIELVSKYL
                     CSDYYGDALGINQYDEVFKNTTLNLGILKVNEEKIVCELDIRYGKNIVLNNIIDRFKK
                     VFCNGWKIEVIAHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            9952..10092
                     /locus_tag="PC366_001858"
     CDS             9952..10092
                     /locus_tag="PC366_001858"
                     /inference="COORDINATES: protein motif:HMM:NF021468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HDF2577387.1"
                     /translation="MNGEGCILSNKITKECYKTGYMIREKSIDTYPDSGRGFMTWDEN
                     GE"
     gene            10604..11698
                     /locus_tag="PC366_001859"
     CDS             10604..11698
                     /locus_tag="PC366_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2577388.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGQSY
                     PDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKDFTVKPFDEVMDEIREI
                     IKKYYSCFPLIFRMGLLIVNHYDIVDEKKRELLISEALEIFIRIQETCNDIDICRQAK
                     SMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNGQMDEARETFQLGAYQN
                     LISLVQNLVGILQNADKLQMKEIERRILAISDIFELDTLSPAIMLSSYLTQTQINLIH
                     GDNEGAIKSLRKYVDLATRDIYPIIIHGDDFFNKLDRWISEIGTGITRDDTIVKAGIV
                     AAIKNNPMFSLLSENKEYKFLIEKLSLLEE"
     gene            11703..11903
                     /locus_tag="PC366_001860"
     CDS             11703..11903
                     /locus_tag="PC366_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLDc_N domain-containing protein"
                     /protein_id="HDF2577389.1"
                     /translation="MENLMEYLPLLIPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISLIGPILYFTIGRGEE"
     gene            11903..12820
                     /locus_tag="PC366_001861"
     CDS             11903..12820
                     /locus_tag="PC366_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577390.1"
                     /translation="MNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKTT
                     TMKMVLGLLEPDSGTIDVCGEKVTYGRTSSNRHVGYLPDVPEFYNYMRPLEYLSLCGE
                     ITGLSKKEIKIRSEELLSLVGLGNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDEP
                     TSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLSE
                     IKSMHGKDRLLLEFASNNEIQKFKSSGGIKSLLKDSEETNMEIVLHGKDIKAIQKTVI
                     STLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            12817..13575
                     /locus_tag="PC366_001862"
     CDS             12817..13575
                     /locus_tag="PC366_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577391.1"
                     /translation="MREYIAFTKKEFKENIRNYKLLSLTILFLVFGIMSPLSAKFMPD
                     LIAHFAPTLKVTTAPTALDSWTQFSGNISGLGTSLTLIVFCNILSNEYSKGTLVIMLT
                     KGLSRSSVVLSKFSIAVIIMTIGFWLSFLCTYGYTMYFWPTANLNHIIFSAFNLWLIS
                     IMYISILILGCVLFRPAFASVLLVLAATAILSLISIPKQIAPYTPNFILSKNIDLVSG
                     KVTPPEFIIPIIVTIVISIVCLLLAVVLFNKKAV"
     gene            13958..15031
                     /locus_tag="PC366_001863"
     CDS             13958..15031
                     /locus_tag="PC366_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HDF2577392.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDEAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKDCEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCVGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKVGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            15101..15364
                     /locus_tag="PC366_001864"
     CDS             15101..15364
                     /locus_tag="PC366_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577393.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            15570..16547
                     /gene="bioB"
                     /locus_tag="PC366_001865"
     CDS             15570..16547
                     /gene="bioB"
                     /locus_tag="PC366_001865"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HDF2577394.1"
                     /translation="MEKYIIKLKNKVLREKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREYFMGRKADLCTIMNAKSGKCSEDCKFCAQSSHYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNNILNIYEGLRENTNLKLCASLGIIDYEQAKMLK
                     SAGVTTYHHNVETCRDNFHNICTTHTYKDRIKTIKDAKKAGLDVCVGGIIGMNESEEQ
                     RLKMVFEIRELNVKSFPINILNPIKNTPMENYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDKVGFNGGVNSAIVGDYLTTVGSGIENDKKMIIEQGFEL"
     gene            16775..17788
                     /locus_tag="PC366_001866"
     CDS             16775..17788
                     /locus_tag="PC366_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2577395.1"
                     /translation="MSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKIMKE
                     KNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANEEGYNIILCNTDED
                     AKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETLKGI
                     VKINNFEGAYIATKHLLDIGNKKIIYLSGPLQNEIAVDRLEGYKKALIECNLSYNSAY
                     VFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDVSVVGFD
                     DIQTSSLISPSLTTVKQPSYDIGYKASEILINCLRGDKKESFDELIFKPELVIRDSTK
                     ESE"
     gene            17830..18720
                     /gene="rbsK"
                     /locus_tag="PC366_001867"
     CDS             17830..18720
                     /gene="rbsK"
                     /locus_tag="PC366_001867"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDF2577396.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIKVL
                     LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGAR
                     FYDGEEIKHVSCISVDVQDTTGAGDTFNGALAVAITEGKKLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEDVEKYLNNK"
     gene            18768..19730
                     /locus_tag="PC366_001868"
     CDS             18768..19730
                     /locus_tag="PC366_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDF2577397.1"
                     /translation="MRVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGGSDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            19784..21295
                     /locus_tag="PC366_001869"
     CDS             19784..21295
                     /locus_tag="PC366_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDF2577398.1"
                     /translation="MSNIILKLSNIAKEFPGVRALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFEGKEIENISPDISKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDINPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLINDLKESGVSIIYISHRMEELFEICDRITIMRDGK
                     TISTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVENLTKNNVFNDISFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKEILEKYIEALKIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGDLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            21279..22277
                     /locus_tag="PC366_001870"
     CDS             21279..22277
                     /locus_tag="PC366_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HDF2577399.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSVFRDQGSAAVGLVIIFIIMSVAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWVGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYIGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKSAKSK"
     gene            22461..23723
                     /locus_tag="PC366_001871"
     CDS             22461..23723
                     /locus_tag="PC366_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2577400.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEMSEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGTADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIGGDCCIICEPSEQNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGVNAIEKAMLLLQDIKELEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFQMDKDSDFVVNAHKILEETLGKKLEIKGSTAGNDARLMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            23743..24486
                     /locus_tag="PC366_001872"
     CDS             23743..24486
                     /locus_tag="PC366_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HDF2577401.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDCNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     IDSEHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            24659..26044
                     /locus_tag="PC366_001873"
     CDS             24659..26044
                     /locus_tag="PC366_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2577402.1"
                     /translation="MDNLNKKFLMEYIDEIQGELRDISDKIWKNPELQYKEYYASNLQ
                     KECLKKHGFSIEGLEGMDTAFVASYGEGRPVIAVLGEYDALDGLSQKVSTTKEPIVDG
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDNCRVHYVTTNGGKMPNIVPDFAEVWYYIRGVKMEHVRDVFGRIVDIA
                     KGAALMTGTIMEYDIISGVYDYIPNTILTDILSQNMKLVGVQNYNEDDYYFADKLAET
                     VSIDKRSSVSSVLSGNKDITKMNLHDEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSISCSINDVMLDELVINKAKKELKD
                     TVGSFEYTPII"
     gene            complement(26381..27025)
                     /locus_tag="PC366_001874"
     CDS             complement(26381..27025)
                     /locus_tag="PC366_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2577403.1"
                     /translation="MNNLDKNNVNEVLDMLLRTRRSIRSFTKEVPSKGLIEEIIETGR
                     LAPYAILSVAKQTDFRHFFVISNNSLQMNKIKTILVDVIKTQISVNEKKAKNNITLQS
                     FITSLKMQVEKGVLGIGTAPYLIIVAERRGIPPIEQKSLSHVMQNMWLKSTALGLGFE
                     LVSVIGRLSDNKDFCDILGVPTGEYGFDACAIGFPTTSVTREGRAIPHPSIKWI"
     gene            27289..27903
                     /locus_tag="PC366_001875"
     CDS             27289..27903
                     /locus_tag="PC366_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HDF2577404.1"
                     /translation="MKKVSIDRRTIRTKKMIRSALAELIDEKGFNNISVTDLTQRADI
                     NRGTFYLHYVDKYDLLERIENEIIQEIEEETKHLDSSNMMEIDTSSEPLPFMVKLFEY
                     FRKNSVIIKSILGPKGDPTFERKIKKFIETNLFEKQKLINFNIDEAIISEEYFIQYIL
                     SADLGVIQYWLEKNMKESPEEMALILARMSLLGPLRAVGIRKDS"
     gene            28124..28264
                     /locus_tag="PC366_001876"
     CDS             28124..28264
                     /locus_tag="PC366_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577405.1"
                     /translation="MKNENISYLALGLCFGVVLGSLFKNLAIGLSFGLVIGVVLDSKK
                     NK"
     gene            complement(28494..28941)
                     /locus_tag="PC366_001877"
                     /pseudo
     CDS             complement(28494..28941)
                     /locus_tag="PC366_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002599264.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            29711..30550
                     /locus_tag="PC366_001878"
     CDS             29711..30550
                     /locus_tag="PC366_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577406.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDKRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFVYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYINILESRGGK
                     NVQ"
     gene            30540..30983
                     /locus_tag="PC366_001879"
     CDS             30540..30983
                     /locus_tag="PC366_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577407.1"
                     /translation="MYSNTYNNENFMRARAFIENSEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            30994..31485
                     /locus_tag="PC366_001880"
     CDS             30994..31485
                     /locus_tag="PC366_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577408.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIVLGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVYSSFIGYYNNRLRKML
                     FKK"
     gene            complement(31687..32415)
                     /locus_tag="PC366_001881"
     CDS             complement(31687..32415)
                     /locus_tag="PC366_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HDF2577409.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            32540..33628
                     /locus_tag="PC366_001882"
     CDS             32540..33628
                     /locus_tag="PC366_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577410.1"
                     /translation="MNFNFAKATNSRLMGSLGLIINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLNNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYDKLLPGD
                     KCEYIDIIKNYKTDLIIEKLYNKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNVVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKELMYDFEVFDEISKSEFVSVYSVNSPEEFAGVFYRENPFLLKSNMNEGIFF
                     TRFNFNNDHVKENVYIINNDMKAIYYLMGNKFFIGTYNENDCNYINEISQSNYSDYIK
                     FEEKFFFEQNALYDFAESGSLDFDDFLE"
     gene            complement(34066..34914)
                     /locus_tag="PC366_001883"
     CDS             complement(34066..34914)
                     /locus_tag="PC366_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577411.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQDELRNDPQISN
                     GYTKIPNNQNINNLYPNNVNHYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNN
                     NTGMPNNMSNNMNSNMGMPNNMPNNMNSNMGMPNNMSNNMNSNMGMPNNMPNNMNSNM
                     GMPNNMPNNMNSNMGMPNNMPNNMNSNMGMPNNVPNNMNSNMGYNMNNTMGIPNFSCN
                     QNMPPNVLMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSIQGIPQATNIEE
                     FDEEEM"
     gene            35113..35478
                     /locus_tag="PC366_001884"
     CDS             35113..35478
                     /locus_tag="PC366_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2577412.1"
                     /translation="MREEINDCNCNIVHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            35501..37888
                     /gene="cadA"
                     /locus_tag="PC366_001885"
     CDS             35501..37888
                     /gene="cadA"
                     /locus_tag="PC366_001885"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HDF2577413.1"
                     /translation="MEANNLIKKEFILGGLNCAHCAEEINNKVSKLQEVKSSNLNFIN
                     KKLIVNIKESFNEDTTIEKIIDIIDSTEPGLDIQISSKENASSKTSIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTVNISNNFKEDDVINKIKEIINSTEPGLD
                     IQVGSTDKVKGRTTEKSGAVNDTNKKELVPLIIGALVYIFGIYQTATGYESQFSNIVF
                     IVAYVIVGGDVLLRAIRNISKGRVFDENFLMALATVGALTIGESSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKFNSEVKVVSPEEVNVGDIIVVKPGEKVPLD
                     GVVVDGVSMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFVPPLVISGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGNFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKVYRGYIVISDEVKEDSK
                     NAIRSLKAIGVKEVVMLTGDNEKVAKNIAQELELDTVYSNLLPNEKVDRLEDLYEGRT
                     EKEKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKIIVMILGAGGVATMWEAIFADVGVALIAVVNAMRAMR"
BASE COUNT        14940 a         3977 c         6872 g        12539 t
ORIGIN      
        1 ttaatagata agatataatt ttaaaaggag tgatataata tgagtaaata tagttcttta
       61 tgggaatatg ttaagaaaaa taatagtcaa tcgtttaaat taacttttga agaaataaaa
      121 gatattgctg gaatagagat agaccattcg tttttgaaat ataaaaaaga attaaatgaa
      181 tatggatatc aagtaggaaa aatctcttta aaagagaaga ctgttatttt caataaaatt
      241 gattaagata taaataatta catataataa aataatttgt attgacgatt attacaaata
      301 aaaataaagt aaatcttata taagatttac tttattttta gatgatattt ttttagcttt
      361 atactataag gtatataaaa ctaagcctat taaaaatgtt ataatttcta ttaccatcat
      421 agaccatatc aatccatcaa gttcataaaa gtaattaagc tttattaaat agcttcttta
      481 ttataatttc tttatttcat ataatataaa tagtattaaa atttttatgg gagttaaagt
      541 aagcatgtat tattacttag atatttgtat aatcaacatc tagtaattta cctttttggt
      601 gaaaatgatt aataagtttt ttaggataat tcattattaa ttcatctgga aaattaattt
      661 cctttaagat attctcagaa tactcatagt tacctatgtc aaaacaaatg tgagcatctg
      721 aagttagtat gattttagca ccatattttt tgcaaagtgt agcaatatac ttacagttat
      781 ccgagctacc atttcttgac acgcctttaa tagaacaatt atttatttct attaagatat
      841 tcttttctat agctaattta atgattaatt catagtcgat tgggtagttt gggtttccaa
      901 ggtgtcctaa tatttcaata ttatcatgct tatttattgc atttattaaa gctttagtat
      961 tattctctaa tgtatttgga gaaaaaacag cttcgtgaaa tgacaagata agataatcta
     1021 accgaggaat tacaaaaggc tctaggtcta tgtttccttt aatatctagt atatttgctt
     1081 cacagcctct taaaattata atgttattta tgattcttgg gatattttga atgttgtgaa
     1141 agtaccatct gtggggagaa ccaggcatct taggaccatg ttcagatgta cctagtatct
     1201 taattccatt ttctttacaa taattaatat tttctagtaa agtgctatag ccatgaccac
     1261 tgactataga gtgggtgtgt aaatctgata aaaaattcat ataaattcct cctctataaa
     1321 agatgagggt aacgtaattt atattataaa acgaatagga aagaaaatca atagttacat
     1381 aattagacaa aaatattaaa atattgtaga attaagctta ataataaatg tttaacagta
     1441 ttactgctta taggggaggt taactatgac acaaaagaag ctatcaagga aagaaaaagt
     1501 tttaatttgc ttgaaaaggt taacagaaga acacttgaac tttaataatg gcattagatt
     1561 tggatttgat gcagaatata tagctactga agtaggtata aatagaagta atgctagtaa
     1621 ggaattaaat caattaataa aagaaagtat tattataaag ataaagggta agcctgttca
     1681 gtacttatat aaagaaagta ttgagagtat tttgggaaag aaactaaata aagggatatt
     1741 tgataatatt aactctataa acgaatatag tgaaaatgat tctatcaaag atgagtatat
     1801 tttagagagt ataaaaaaag agaacaatat ttttaattta gtaggatgtg atggaagttt
     1861 aaggtcccaa atagaacagg ctaaagcagc agtaatatat ccacctaagg ggttgagtac
     1921 attaataata ggacctacag gagttggtaa atctatattt gcagaatata tgtataagta
     1981 tagtttaact ataaaagaag atagtgataa tgcaccattt atcatattta actgtgctga
     2041 ttattctgat aatcagcaat tattattagc gcagcttttt ggatatgtaa aaggagcatt
     2101 tactggagct gataaagata agtatggtat tgtacatgaa gctaataatg gagtattgtt
     2161 tttagatgaa gttcatagat tatctgcaga gggacaagaa atgctatttc tgcttatgga
     2221 taaagggata tatagaaggt taggagaggc taataaggta cacgagtgta gagttatgat
     2281 aattgcagcc actacagaag acccagaaac agcaatgttg gaaacgtttt taagaagaat
     2341 acctgtaact ataaagattc cgtctttaga ggaaagaggc tttcaagaga gaatgaagct
     2401 tatatgttat ttttttaaag aagagagtgt taggattggt gttaagttaa aggtttcaaa
     2461 agaagttatt aaggcattta ttttatataa gtgtaaggga aacataggcc aattaaaaag
     2521 cgatatacaa ttaatttgtg caagagcttt tttagattat atgacctata aaagggaatg
     2581 tgtatatgta aggctctctc ttctaccaaa taatattaga gaatcattat atggaaataa
     2641 tagaaaagag gagtttgtac aaaatttcag ttttattgga aaagatgata ttattttttt
     2701 accagaagaa aaggattttg aaagtgaaaa tttattaata gaaaataaaa aatatgattt
     2761 agatttttat ggaatgataa aagaaacttg gaataaactt caacaagaag gtattaaaga
     2821 gtcacaaatt agaagtgtta tagatggaga catacagaag tattcctata atttaatgaa
     2881 tacttttata tataataata gtaatcaaac agcttataac aacattgtta atgattcaat
     2941 tgcaactact gtaaaatata ttttacaaaa gcatgataaa tggagcaaaa gagaaggatt
     3001 agataaatta ataaaagcta tagccttaca tattcagaat ttaattgaaa gaataaagat
     3061 tggaaatata gtaaagcatc ctaataaaga tgaaattatg aaggaaagag catatgaata
     3121 taacatagca aaagaaatat tatctaacat gtcattaatg tatggagtag agtttccaga
     3181 agatgaagca atttttttag caacatttct ttatttatcg tatgtgggat taaatgagga
     3241 gagtatagca atattagtca taatgcatgg tgaatctaca gcatctagca tggtgaatgt
     3301 agccaatact ttactggatt gtaaccatgc agtggcaatt aatatgggat tagaagatag
     3361 agttcaggat attttagtac aagctgtaga aatagccaat aaaattgata aaggaaaggg
     3421 aattttaatt ttaactgata tggggtctat tttaacattt gctaaagtta ttcgtgatgc
     3481 tacaggaaaa gaagtaaaag cagtagatat ggtaagtaca cctattgtaa tagaagcaac
     3541 tagaaaggct ctaactccag aaatgacatt agagaaatta tattttaata ttatagaatc
     3601 tataaagaaa cattatggag atatggaagt tacatatgct gaaaaagata atggtggtag
     3661 atattttgat agactactaa ttgataatat tagtaaaact ttgacttttt taaatgggga
     3721 aaaggcttat tttatattaa aagaagtaat taatagaatt agtgaacact attctttagt
     3781 aattcaagat gaacttttag taaagtttat atttcattgt tcatgtatga ttgaaagagt
     3841 aataataaaa gagtctttag tttataaatc atatgaagaa agaattagta gaaataaaga
     3901 attatattta gttataaaag aaagttttaa gctagtagaa gagacattcg atataattat
     3961 ttcagatatg gaatatgcaa atatattaga tatatttgaa tcacaatatg atacagataa
     4021 attcaaaagt tgatacaaaa tttaaaaata gccaaaaggc tatctttttt ttactttttt
     4081 tgatacagat ttgatacagg ttgaaaaaat cttttgatac atatcgaaat aataagtttt
     4141 taaaaaaaat tgagtaaaaa gttttgatta aatcctgtaa aatagccatt tattattgat
     4201 acacataagt tggcacggca attgcttata taaaaagtga caagaaaagt gaggtgaaat
     4261 tggtgatagg aataatagtt atgactcatg ggagttttag tgaagaaatt ataaaaagct
     4321 gtgaacttat tgcaggacca gcagaaagaa cagcagcaat taaactaaat aggaatgata
     4381 atattgaaga cttaaataaa aattttgtag aaaagttaaa tgaattagat gaaggtgacg
     4441 gagttttagt attagctgac ctattaggag gttcgccaag taatgttgca agtttaaacc
     4501 ttaaaaaagg tggcaagttt catgcactta ctggagtaaa tcttccaatg ctacttgaag
     4561 ctttaattaa tagagaggga aaaagtttag aagagttagc agaagcatgt attgaagcag
     4621 gacaaactgg tataaacaat attaataaag ttcttagctc aatgtaatag aaaaaggagt
     4681 ttgattaaaa atgtctttag taaaatattg cagatgtgat gatagattaa tacatggtca
     4741 agtgatatat aaatgggtta agcatctagg tgtaaaaaag atagtagtag tagatgatga
     4801 aacaaccaat gatgttattg ctaaaggttt gataaaaatg gcagcaccaa agaatattga
     4861 tttatcaata ttaactgtaa gtgaatcaag gagatatttt tataataatc aagctgatga
     4921 taacgttttt gtattaatta aaaatttaga tactgcaaat agaatgatag aagaagggat
     4981 taatatcaaa aaacttattg ttggaagaat acctacagga ataggaaaaa agaaaatatc
     5041 tcaaaatgta tacattaata aaaaagagtt tcttttaata gatgaattta ttaaaaagaa
     5101 tattaatgta tcaattcaaa tggtacctga tgaagaagaa gtagaattaa accaaaatat
     5161 taatcgctat aaaggagagt ttatttagca atgaataaat ataaggtaat tatactgtgc
     5221 catggaactt ggggaaaagt cttagtagaa gaaacaaata aaaactttgg attgtcaaat
     5281 caatatgaag ttttatcact aagttctgaa aaagatgttt ctgtatttat gaaagaggtt
     5341 gaagaagtag tagataaaga agatgtgaaa attataatat cagatttata tggaggatct
     5401 acatcaagtg ttgcaatagc tgttgctata agaagaggaa tagatgcaat aaatggactt
     5461 agcttacaga caattttaat cgtagatgaa gaattaagca aagaagataa attacataca
     5521 ttaccagaaa gaatcgtcaa aaaaaataat aacctttgtg tggatttaat taaagaattt
     5581 aaaaaaatat aaattatgag gtgaatataa tggcaaaaat aacattagta agagtagacc
     5641 acagattaat tcatgggcaa gttataacaa aatgggtaaa aatcgctcaa gctcaaaaaa
     5701 taataatagt tgatgacttc ttaggtcaag atgaatttat ggctgacata tataaaatgg
     5761 cagcaccatc aggagtagaa gtagttattt taacagcaga agatgcggga caagcattcc
     5821 aaaacaacac tttaggagat aaaaatatat ttattctatt taaaaatgtt gatatggcaa
     5881 ataaggctta taaagctgga cttaaatatg aaaagattca attaggaggt attccaaatg
     5941 aagcaggaaa gaaaatggtg tttacagctg tttcattagg aaatgaggat gtagaacaac
     6001 ttaatgaact taatgaaaat ggggttgaaa tagtcctaca agttatacca gaggaatcat
     6061 ctatgacata tgaaaatgcg ttaaagaaat ttaaataaaa aatataaatt aggaggaatt
     6121 ataaatggaa tctgttttga tgttggcaat tgtaacagga ttatggtatt ggtttgcagc
     6181 aggtcttgca gggtataccc ttttctcaac actaaagtct cctttattta taggttttag
     6241 ccttggatta ctttggggtg atgtaacaac tggtatgatt gttggtgcaa gtatagaaat
     6301 ggtttatcta ggaatggtcg cagcaggggg aaatattcca tcagataaat gtctagctgc
     6361 tcttattgca ataccagtag cacttcaaac tggtgttaat gcagaagttg cagtatctat
     6421 tgcggtacct ttaggtgtta taggagtatt agttaataac ttaagaagaa ctggtaatgc
     6481 tgtattggtt cataaggcag ataagtatgc tgaagaaggt aatacaaaag gcatctggag
     6541 atgtgcaaca ctttattctt taatatttgg gtttgtttta agatttccaa tagtttttgt
     6601 atgtaacttt tttggagcag atttagttca atcattatta gatgttatac cacaatggtt
     6661 aatgaatgga ttaacagtaa tgggcggtat attacctgca ttaggttttg caacaacaat
     6721 atttactata ggtaaaaata aattcttacc aatgtttatt ataggatttt ttatggttca
     6781 atattttgaa atatcaatta ctgcagctgc aatatttggt gtttgtatag ctcttttaat
     6841 tacctttatg aaagaagaca aaagggtagg tgaagtataa tgcaagaaat aaaaaataaa
     6901 gaagttaaaa atggacaagg tccaactgaa gttaataaga caagagtact cacaaagaaa
     6961 gatgtaacaa aaacatacct aagatggtgg tggacagcag agttatctaa ttcttttgaa
     7021 agaatgcaag cattagcagt ttgtgcaagt ttcactccgg ctttagaaaa gttatataag
     7081 aaaaaagaag atttagtaga tgcattaaag agacacttac aattttttaa tactcaagct
     7141 atatggggag gattaattca tggtacagtt ttagctatgg aagaagagaa agctactgaa
     7201 ggaaaaatcc caggagaagt tatttcaggt gttaagaatg gtcttatggg acctttggct
     7261 ggaattggag atactttaga ttttggtaca tttcaaacaa tattcttagc tttaggtgct
     7321 tcatttggag cagaaggaag tgttataggt gcatttttcc caataatgtt tagtatatta
     7381 ctattttgcg aaggttatta cttatttcat ttaggatatt ctttaggtag agattcaatt
     7441 aagaaaattc tatcaggtgg tattgtcaat aagataattg atggtgcttc aattctagga
     7501 atgtttatga tgggagcatt atctgcaact acagttaagc tttcaactcc gctatcattt
     7561 gatattggtg gtaaagcaat tgttgttcaa gatacattaa atatgattgc tccaggttta
     7621 ttaccacttg gtgttgtatt cttcgtatat tggggaatga aatacaagaa gtggacaata
     7681 actaagttat tagtaatttt agttgtatta gcattggtag gatcattcat tggaatattc
     7741 taattcacag tgattaaaat atagaattta attttaggag gagaaagaaa tgtcagaaaa
     7801 aatgtataca gaaaaggaat atttagaagg aattagagga gcaacaggag aaagagcagt
     7861 atggttctat cttcttatga aagaagctga aaaattagga gctaatccag atgatatatg
     7921 taaagaagca atatatggat ttggtaaaat gagaggtcaa aaatataacg tagcagatac
     7981 tccaggaaaa atggcagaaa tgttatataa cagtaaagga caaaaagtgt ttgaaatgga
     8041 attagtagaa aatacagatg agaatggcgt tttaaaattc catcactgtc cattagatgc
     8101 tgcttggaaa gaatatggat taactaaaga agaaagaaaa gaaatttgta gattagcttg
     8161 ttatggggat tatggaagag ttgactgtgc acaaggtgtt aaattagatt ttgctcaaaa
     8221 atgtgctcat gatgatgaag tttgtgaatt agtatttaca aaaaaataat ttttaatgct
     8281 aaaagcctgt tctttaagga caggctttaa aaagatagaa agtaggttga tttatggata
     8341 taagcagaag tgtagataat agtttaaata gaaccataga atttctaaaa gaattgataa
     8401 aaattgattc acaacaaggt gaacctattt cacaatgtcc ttttggtata ggacctaaaa
     8461 aatctttaga taaaacttta gattactgtg ctagtttagg ttttagtgtt aaaaatattg
     8521 ataattatat tggatatgca gaaattggag agggagagga attaataggg attccaatgc
     8581 atttagatat agttccacca ggagaggggt ggagtgtaga cccattttcg ggagcagtaa
     8641 ttgacaatat tatttatgga agaggtgtca tagataataa gggtgctgta tctatgctta
     8701 tacatgtatt gaaaaacata gaggatatgt atcctacaat taataaaaga ataagattaa
     8761 tttttggtac aaatgaggag acagatatga aatgtatcaa atattactta gataaaggtg
     8821 aagaaattcc aagtatggga tttactccag atgctatgta tccagtggtt aatggagaaa
     8881 aaggaagggt tcatataagg atagaaaaag aaattaaaat tgacaaaagt aaaccttaca
     8941 taatagtaag gggaggaact aaagaaaatg ttgttccatc tcattgtact gcaaaaatta
     9001 ttaatggaat tatttcagag ttaactacta aaggagtagc tgtacatgca agtaatcctg
     9061 aaaagggaga aaatgctata tctaaaatgg taataaagat agttgaggat aatatggatt
     9121 ttcagcatag agaagatata gaattagttt caaaatacct ttgtagtgat tattatggag
     9181 atgcattggg gattaatcaa tatgatgagg tattcaaaaa cactacctta aatttaggaa
     9241 tattaaaagt aaatgaggaa aaaatcgtat gtgagttaga tataaggtat ggtaaaaata
     9301 tagttttaaa taacataata gatagattca aaaaggtttt ttgtaatggt tggaaaatag
     9361 aggttattgc tcataaagac ttacattatg tggatgagag taatttagta cttaaaaaat
     9421 tattagaagc ctatgaagaa gtaacagatg aaaatggata tacaattgct atgggtggtg
     9481 gcacatatgc aagttggttt aaagatatgg tggcgtttgg acctaagttc ttagcgtata
     9541 aaactggtgg tcatggagta gatgaaagag taccaataaa tcatatacga aagaatatgg
     9601 agatatatac tttggcttta ataaaactat tagaattgta aaagaagaag agactttatg
     9661 tgcaaattta cagatatctt aaaaagagag ataaaacgag ttcaacttta tttaaatgtt
     9721 caacaccatc aaatggggct gtctcaaaat agagataagc ctcttgctta ttattgaaat
     9781 gatgaaaata tattttactt catacaaaaa agagtgcctt atgaagtaaa aagttaattt
     9841 tgagacaccc tcatttgatg atgttgaaga gaaaataagt atgaaattat taaaaaaaga
     9901 tgattttata aaagttaagg ttgaaaataa aagttaattg aatggaatta gataaatgga
     9961 gaaggctgta tactatctaa taaaataaca aaagagtgtt ataaaactgg ttatatgatt
    10021 agagaaaagt ctattgatac ttatccagat agtggacggg gatttatgac ttgggatgaa
    10081 aatggagaat aataaaaatt atagtttata caatttaata agatatatgt acaagcagtt
    10141 aatctaaatg attgactgct tttcttttat agatttttat ataatagaca attactaata
    10201 catgatagtt gcctgttata attagaggaa tagatacgaa taataacttt ataaaagaat
    10261 taaatggaaa attgaagagt tatattcagg attttaaaaa gaatatgaaa tgagaaatga
    10321 aaataaggtg tttatattaa aagaggtttt acacaaaata cttaaaaacg tgataaataa
    10381 aaactgtatt tagataaatt aactactagt tttatatata atatggattt tgtttacaaa
    10441 gtttacatat ttcacaaaat atttttaaaa tatatttaaa aatatatttt atatacttgt
    10501 tcgtttgttt ctctgtggtt gattttttcg tcaaaagtca acttcaaatc gcttgttagc
    10561 tttacatgtt taaggatata attatacata aggagggatt gacatgaatg aattaaacat
    10621 cgcaaaaacg ctgattttaa agcgtaaaga aaaaggaatt acacaagatg aacttgcaaa
    10681 ttatataggc gtttctaaag cttctgtatc taaatgggaa actggacaaa gctatcctga
    10741 cataaccttt ttaccgcaac tcgcgacata tttcaacatt accgttgatg agttaatatg
    10801 ttatgaacct caaatgatga aggaagatat taataaactg tataataaac tgtgcaaaga
    10861 ctttacggtt aaaccgtttg atgaagtcat ggatgaaata agagaaatca taaaaaaata
    10921 ttattcatgt tttcctttga tttttcggat gggtctttta atagttaatc actatgatat
    10981 tgtagatgaa aaaaagcgtg aactattaat tagtgaagca ttagaaatat ttattcgtat
    11041 acaggaaact tgtaatgaca tagatatttg ccgtcaagca aaaagtatgg aggcaacttg
    11101 ttatatattg ttaaatcaac ccatacaagt gattgattta ttgcaaaaca gcaattttcc
    11161 catgataaat gaatctatac ttcttgcaca ggggcaaatg atgaatggtc aaatggatga
    11221 agcaagagaa acatttcaac ttggtgcata tcagaacctt atatcattag tccaaaatct
    11281 agtgggtatt ttgcaaaatg cagataaatt acaaatgaag gaaatagaaa gacgtattct
    11341 agcaatttca gatatatttg agcttgatac attatctcct gctattatgc tttcttcata
    11401 tttaacacag acacaaatta atttaataca tggggataat gaaggagcta ttaaatcatt
    11461 acgaaaatat gtagatttag caacacgtga tatataccca attataatac atggggatga
    11521 cttttttaat aaacttgaca gatggatttc tgaaattgga acaggtatta cacgtgatga
    11581 tacaatcgta aaagcaggta ttgttgctgc tattaaaaat aatccaatgt tttctttatt
    11641 aagtgaaaac aaagaataca aatttcttat agaaaaatta tctttattgg aggaataaga
    11701 ttatggaaaa tttgatggaa tatttaccac ttttgattcc tgttattatt ttagatttaa
    11761 tacttataat tactgcactt gttcatgtat tgagacatcc aaattataaa attggaaata
    11821 aggcaatatg gattattgta gtactgttta ttagtctaat aggaccaatc ttgtatttta
    11881 caataggaag aggtgaagaa tgatgaatat tgtctcaata aatggattat caaaaggttt
    11941 tggtaatcga aagataatag ataatctaaa ttttactgta ccagaagggt cagtctttgg
    12001 gtttgtaggt aagaatggtg caggtaagac tacaacaatg aaaatggtac ttgggttact
    12061 tgaaccagat agtggaacta tagatgtttg tggtgagaaa gtgacatatg gaagaacaag
    12121 ttctaatcgt catgtaggtt atctgcctga cgttccagag ttttacaact atatgagacc
    12181 acttgaatat ctttctcttt gtggtgaaat tacggggctt tcaaaaaaag aaataaagat
    12241 aaggagtgaa gagttgttat cacttgtggg gcttggcaat gaaaagagac gaataggtgg
    12301 gttttctcgt ggaatgaagc aacgacttgg tatagctcaa gctttgcttt cacgtcccaa
    12361 attacttatt tgtgatgaac caacaagtgc acttgaccct gttggtcgaa aagaaatatt
    12421 agatattatg cttaaaatca aagactcaac aactgtaata ttttcaacac atatactatc
    12481 agatgttgaa agaatctgtg accatgttgc tatactaaac aaaggaagca ttgctcttag
    12541 cggtacactt tcagaaataa aaagtatgca cggaaaggat agacttttac tggagtttgc
    12601 aagtaataat gaaattcaaa agtttaagtc tagtggtggc attaaatcct tactaaaaga
    12661 ttcagaagaa actaatatgg aaattgtttt gcatggtaaa gatataaaag caatacaaaa
    12721 aacagttata tctacactcg cagaaatgaa tctttgtcca gtaaagatgg aactaataga
    12781 attgtcactt gaaaatttgt ttttggaggt agtaaagtga gagaatacat agcatttaca
    12841 aaaaaagagt ttaaggagaa cataagaaat tataaattac ttagtttgac tattttattt
    12901 ttagtatttg gaataatgag tcctctttct gcaaaattta tgccagactt gattgctcat
    12961 tttgctccaa ctttaaaagt tactactgca ccaactgctt tagattcttg gacacagttt
    13021 tctggaaata tttctggtct tggaacgagt ttaactctaa ttgttttttg caatatttta
    13081 tcaaacgaat attctaaagg aacactcgtt attatgttga ctaaagggtt atcacgttca
    13141 tctgtagtat tgtctaaatt ttctattgca gtaattatta tgacaattgg tttttggttg
    13201 agctttttat gtacttatgg atatacaatg tatttttggc caactgcaaa tcttaatcat
    13261 attatatttt cagcatttaa cttatggtta attagtatta tgtatatttc catattaatt
    13321 cttgggtgtg tactatttag accagcattt gcaagtgtgt tacttgtatt agcagcaact
    13381 gctattttga gtttgatttc tattcctaaa cagattgcac cttatacgcc taatttcata
    13441 ttatcaaaaa atatagattt agtttcaggt aaagtgacac ctccagaatt tattattcca
    13501 atcattgtaa caattgttat ttcgatagta tgtctgttat tagctgttgt tttgtttaat
    13561 aaaaaagcag tttaaggata tttttattat aaatacaaat agtgctgtat tgtgggaaaa
    13621 tgtgtttagt attgtagaag aatatattta agtaaaaaag aggctgtctc aagatagaga
    13681 aataagcctc ttttttattt tagtcctcct cactatactt tataataatt aagttattac
    13741 cttaaggaac tatctaaaaa aagagatata gattataatc taatgcttat cagttatttg
    13801 aggtgtttag tatatagagt ctaaagtagt gaaggactaa aataatattg ttttcattaa
    13861 ataaagataa gaatctttaa ttgtggtaaa atatactaaa aaatcatttt aaaagtgata
    13921 aaattatttt aagtaaatat tttaaagggg tgtagatatg gaaaagtcaa aagtatattt
    13981 ttgtgattta tactcaaatt cgcaaaataa aaacgtacca aacaatgtaa gaagattatt
    14041 tgatgaagca ggattcaaag atttaataga aaagaatgac caagtcgcaa ttaaacttca
    14101 ctttggagaa aagggaaata ctacatatat gagtcctgtg gcagttagac aagtggttga
    14161 taaggttaaa gactgcgaag gaaagccatt tttaacagat acaaatacac tgtatacagg
    14221 gagtagaaca aattctgtag accatcttac aactgctata gaaaatggat ttgcttatgc
    14281 agttgtaaat gcaccagtaa taattgcaga tggattatat agtagaaatt atgagaatgt
    14341 aaaaatagac aaaaaacatt ttgaaagtgt aaaaataggt ggagaaattt ataattcttc
    14401 tgcaatgata gtaatgagtc attttaaagg tcatgaagca gcaggttttg gaggagcatt
    14461 aaaaaactta gctatgggat gtgcaagtgc agcaggaaaa caaatgcaac attctgatgt
    14521 tactccagta gtaaaggaaa agaagtgtgt aggttgtgga aagtgtgtta attcttgtcc
    14581 tacaaaagct ataagtatag tggataaaaa agcagttata gattctgatg tatgttatgg
    14641 atgtggagaa tgtccaactg tctgtccaac tagagcagta actatacaat gggaaagtga
    14701 ctcagatgtg tttgtcgaaa agatggcaga atacgcttat ggagcagtat caaataaaaa
    14761 agacaaggta gggtatataa cttttgttat gaatgtaact ccactttgtg attgtgtacc
    14821 ttggtcaggt agaccaattg cccatgatat aggaatatta gcatcaacag accctgtagc
    14881 tattgaacaa gcatgctatg atttgatttg taaggaaatg ggtcatgatg ttttcaaaca
    14941 tgaacatcct catgtaaatg gaactagaat aatagactat gcatgtgaaa tgggtatggg
    15001 aagtaaagaa tatgaattaa taaaattata agaatagtag cacttaaatg catataatta
    15061 ttgtaagaga aatctaaaag tatcaaagga gtatgcattt atgaaaattt actatgagaa
    15121 ggaaaacagc aagaaggcta atgtaaacaa tattccaagt gtatttgcgt ttaattttct
    15181 aagaaacttt ttgactagca aagagtatga ggaaactaga aaagaatatt ttataaataa
    15241 tctaacaaaa agtcaggtta atcaagccat gaaggattta aaatggctat ttagagaata
    15301 tgaaggctta gaggttatta caatggaaag cttggatgga gttaagacaa ggatagtttt
    15361 ataaaccagt aagaattata ttctaataaa aaatactgct ttaataataa tatgtataat
    15421 ctatatacta atattatttt gaagcagtat ttttttgtgt atagtaaact tgtgtctaaa
    15481 ataaagttga ccaataaatg ttatatatgc aatactatat ataataagta aactacataa
    15541 aaatattaag ttgacaaata ggaggatata tggaaaaata cataataaaa ttaaaaaata
    15601 aagtattgag agaaaaagaa ataagttatg aagaagctct taatttaata agccttgata
    15661 caaataataa aaacgatttt gatattctat taaaatctgc aaatgaaata agagaatatt
    15721 ttatgggaag aaaagcagat ttatgtacga taatgaatgc taaatctggc aaatgtagtg
    15781 aagactgtaa attttgtgct caatcatctc attataaaac tggtgtagaa gaatattcat
    15841 tattagatta caatgaaatc ttaaatagag ctaaagagat ggagagtaaa ggagtgcata
    15901 gattctcatt ggttacaagt ggtaaaggta tgtcaggaaa ggagtttaat aatattttaa
    15961 atatctatga aggattgagg gaaaatacta atttaaaatt atgtgcatct ttaggtatta
    16021 tagattatga gcaagctaaa atgttgaagt cagcaggtgt gactacatat caccacaatg
    16081 ttgagacgtg tagagataat tttcataata tatgtacaac acacacatat aaagatagga
    16141 taaaaactat aaaagatgct aaaaaagctg ggctagatgt atgtgtaggc ggtataattg
    16201 gaatgaatga gagtgaagaa cagagactaa aaatggtttt tgaaatacga gaattaaatg
    16261 taaaatcatt tccaataaac attttaaatc ctattaagaa tacgccaatg gaaaattatg
    16321 atgtattaga accaatggaa atactaaaaa caacagcagt atttaggttt ataattccta
    16381 atgtgtacat aaggtatgct ggtggaaggc tatcattaaa gggatatgac aaagttggat
    16441 ttaatggggg agtaaattct gcaattgttg gtgattattt gacaactgtt ggaagtggga
    16501 ttgaaaatga taaaaaaatg attatagagc aaggatttga actttaataa atactactta
    16561 aattaattaa tatactttta gataattata aaagtatatt aatttttttt gcagattaat
    16621 ttaaatatta aaattgaatt ataagttgca atattttgaa aaaagggaaa aatatcaaaa
    16681 tttatataaa atggttgcaa atgggaaaag gatgtgatag tatctaggta accggttaag
    16741 taaaacggtt tcctaaattt tgggggtgaa cttcttgagt ataactataa aagaaattgg
    16801 cgaattggct ggtgtttcta aaacaactgt gtcaaaagtc attaataata aagatgaaaa
    16861 tataagtcag gcaacaagag aaaaaatttt gaaaataatg aaggaaaaaa attatgtacc
    16921 aaataaatta gcacaaagtt tagtaactaa aaaaactaat actatagggc ttcttatacc
    16981 agatatacga aatccattct ttacagatgt atcaagaggt gtagaagaca aagctaatga
    17041 agaaggctac aatataattt tatgtaatac agatgaagat gctaaaaaag aatatgaagg
    17101 aataagaaca ctatcagaga ggatgataga tggaattata tttgcagcat cttcaaatac
    17161 aaactggaaa gaagcaaatt ataaagatat aaaaatacca actgtcttga ttgataagaa
    17221 gataagtatg aacaaagaaa ccttaaaagg aattgttaaa ataaataact ttgaaggggc
    17281 ctatatagct acaaaacatt tattagatat tggaaataag aaaataatat acctaagtgg
    17341 tccacttcaa aatgaaatag cagtagatag attagaagga tataaaaagg ctctaatcga
    17401 gtgtaattta agctacaatt ctgcttatgt atttgaagga aaatataaga ttgaatgggg
    17461 acaagaattt ataaaaaatt tagaaaagat agattttgat gcaatatttt gtgcaaatga
    17521 tttgattgca ataggtgtca taagaggtct taaagaaaga gggttaagta taccaaatga
    17581 tgtaagtgtc gtgggatttg atgatattca aacatcaagt ctaataagcc cttctcttac
    17641 cacagtaaaa cagccgtctt atgatatagg atataaagcc agtgaaatat tgataaattg
    17701 tttaagagga gataaaaaag aatcatttga tgaattgatt ttcaaaccag aattagtcat
    17761 aagagattca acaaaagaaa gtgaataaca gcacgagaga cataaataga tatgtaaagg
    17821 agtaatgtaa tgggaaacat agttgtcata ggaagtgtaa acatggacat ggtatgttct
    17881 gtagataaaa gaccagaaaa aggagaaaca gtattaggta atagtttttt tacatcacct
    17941 ggagggaaag gggctaatca agctatctca gcttctaaac taggagcaaa tgtaaaaatg
    18001 atatcatgca taggggaaga tggcttagga gaggagttaa taagaaattt tagaacgaat
    18061 aaagttgatt atagtttagt atccagaaat aatcacaaaa gttctggtgt tgctgttata
    18121 acattatgtg aaaatgataa tagtattgtt gttgtaccag ggacgaatga gctagtagat
    18181 atagaattaa ttaaaaagaa tgaagaagag ataaagaatg cagatatagt attgctacaa
    18241 ttagagattc cattaaaaac aataaattat gtagtgaatt tctgttttga aaataggatt
    18301 aaggttttat taaatccagc accagcagta aaactaaatg aagatataat agaaaaagta
    18361 acttacttaa caccaaatga acatgaatat aagatagttt ttgacacaaa tgaagggata
    18421 gaagaagtat taaaaaaata tccaaataaa cttgtaataa cagaaggaaa aaatggagct
    18481 agattttatg atggtgagga aatcaagcat gtatcttgta taagtgttga tgttcaagat
    18541 accacaggag caggagatac atttaatgga gcattggcag tggctataac agaagggaaa
    18601 aaattatata cagcagtaga atatgcagta gtagtatcag gtctttctgt aactaaacta
    18661 ggtgcacaat ctggtatgcc ttataaagaa gatgttgaaa aatatttaaa taataaataa
    18721 aaatctaatt tgttcaaatt taaaactatt aaaaatggag gttaattatg agagtgagaa
    18781 aaattttatc tttaggaatt gctggaatac tagcaatagg aatgttaaca gggtgttcaa
    18841 tggaaggacc aagtaaatca gataataaag gtggttcaga caagaaagat ttaactattg
    18901 gagtatctac aataactctt caacatcaat tttttataga tattgatgag ggaataaaag
    18961 aaaaagctaa ggaattaggt gtgaaagtta tagtaaatga cccagaccaa gatgtagcta
    19021 agcaaacatc agcaatagaa gattttatac aacaaaatgt agatggaatg atagtacttg
    19081 gaactgataa ttcggctata gtaccagcag tagaaggagc atttgaaaaa atgccagtag
    19141 ttacagtaga tgctgtatta aatactgaaa atattacaag ttatgtagga acagttagtt
    19201 atgatgctgg taaaaaatta ggggaataca ctaaaaaata catagatgaa aagttaggtg
    19261 gaaagtcaga aatagcaata gtgacagatt taaaatctca aatacaaatg cagagaatag
    19321 atggatttaa agatgcgtta aaaggttcag caaatgttaa gatattaaat tcacaaccag
    19381 gatatgacag agaagaatct cttaatacag tagaaaactt aattcaatct aatccagatg
    19441 tagatataat atatgcaaca gctgaaaata gtgtactagg agctaaagct gcacttgaat
    19501 ctgcaaaaaa taaggatgtt aagattgtag gatttgactt aactgaagaa gcatcaagtg
    19561 gaataacaga tggaactatt cttgctatga ttcaacaaca acctaaagag atgggacgtt
    19621 tagctgtaga agcagtagta aaagctataa aaggggaaaa ggtagaaaag aatataccag
    19681 taccagcttt actttatgat aaggaaaata taaaagactt taagaattag taaaataaaa
    19741 tgagattatt tgaaagaaat cctatttaaa aaggagtgtc attatgagta atataattct
    19801 gaagttaagt aatattgcta aagaatttcc tggtgtcaga gcattagata atgttaattt
    19861 tgagttattt catggcgaag ttcatgcact actgggtgaa aatggtgctg gtaaatcaac
    19921 aatgataaag attttaactg gtgcacattc gaaaacttct ggaaaattta tttttgaagg
    19981 caaagaaata gagaatatat ccccagatat ctctaaaaag ataggtataa atgccatata
    20041 tcaagaacta acagtttttg acgaattaac agtagcacaa aatattttta tgggaaaaga
    20101 aataaatggc aaagtcttaa ccaatgacaa aaaaatgaat gaagaggcta aaaagatttt
    20161 cgataatatg ggaatagata taaatccaaa tagtttagtc aaagagctta gtatagctca
    20221 aaaacaaatg gtagaaatag caagagtttt atcatcagaa actaaagtat taataatgga
    20281 tgaacctact tcttcaataa gtaaaaaaga gactgaaata ctttttagac ttataaatga
    20341 tttaaaagag agtggagtta gtataatata tatatcccat aggatggaag aactctttga
    20401 gatttgtgac agaataacta taatgcgaga tgggaaaacg atttcgactt tgaataccaa
    20461 agatgtatcg tctgaggaag aattagttaa tttaatgata gatagaaagc tagaccaatt
    20521 tttcccaaaa agaaaagtag aaataaaaga agaaattatg cgagtggaaa atctaactaa
    20581 gaacaatgtt tttaatgata ttagctttaa tataagaaaa ggtgaaatat tgggaatagg
    20641 tggactagtt ggaagtaaga gaagtgaaat agtagaagct atatttggac ttagaacata
    20701 tgattctggg aaaatatatt taaacaatga agaagtaaag tttaaaactc catcagatgc
    20761 aatagaaaat ggactgggat taataacaga agatagaaaa ggtactggat tgtttttaca
    20821 aatgagtgtc aaagaaaaca caactatggc tgggttaaaa aagatatcta agtttaaatc
    20881 aattatagat agaaaaaagg aaaaagagat tttagaaaaa tacatagaag ctttaaagat
    20941 aaaaacacca catatgaatc aagttataca aagtttaagt ggtggaaacc aacaaaaagc
    21001 tataatagca agatggcttt tattacaacc agatatattg attatggatg aaccaaccag
    21061 aggtatagat gtaaatgcta aggcagagat atacaatcta atgggagatt tagtggagag
    21121 tggtgtaagt ataataatga tatcttctga aataccagaa ttaatatcaa tgagtgacag
    21181 aataatggtt atgagagaag gtcatataag tggattttta gaaggtgaag aaatggttga
    21241 aaataatgta ttaaaattgg ctttcggagg taaaattaat gagttcaata actaagcata
    21301 aagaagaaaa atcttctcca ttattgacaa aattaacaag tgtatttaga gaccaaggga
    21361 gtgcagctgt aggacttgta ataattttta taataatgag tgtagcttca tctaactttt
    21421 taactttaga taatttaatt aatgttggaa gacaaatatc aataaatgca atacttgcag
    21481 taggtatgac atttgtaata attacaggag gaatagattt aagtgtagga gcagtaattg
    21541 ctttagtagg tacattttgg gctacaacag tagtgaatta taatgcacct atatgggtag
    21601 gtatgatact tgcattagca atagggacaa tattaggagt cataaaaggt gcaattattt
    21661 caacacaaaa actacctcca ttcattgtaa ctttagccat gttaacgata ataagtgggg
    21721 caagctttgt atttacagga ggaagaccta tatcagtaaa tacagatgca tttaagatgc
    21781 tcggtagagg atatattgga ccaataccaa taccagttat aattatgatt atagttgtaa
    21841 tagcaggaca ttttctatta aaaagaacta attttggacg tcatgtacat gcagtaggtg
    21901 gaaatgaaga ggccgctaga ttatgtggag taaaagtaaa taaagttata gtaaaagtat
    21961 acgcactagc tggactacta acagcattag ctgggataat actatcatca cgtttggcat
    22021 caggttcacc aactgttgga gatggagcag aattggatgc tatagcagcc gttgtgcttg
    22081 gtggtactaa tatgatgggt ggttctggtt ctatagtagg tacatgtata ggtgtcggaa
    22141 taataggaat attaggaaat ggattaaact tattaagtgt atcttcatat aatcaaatga
    22201 ttataaaagg tttggtaatg ttatttgcta tatggataaa taatataaaa ttaaaaaaat
    22261 cagctaaatc taaatagtaa ttaaatttta gcttataaac tataaaaatt attaagtttt
    22321 tgtatatatt tttatacttt aatttgcata catctttata cattgaatgg gaatatgcta
    22381 agtgaaaaag tttactatgg cttaaataga tgagattaga cttgaaattt taaatgtaaa
    22441 aataaatctt aggaggaaat atgaaaaaaa ttctcttaga tacattaaat agtaaaaaac
    22501 aagaatacat agattattta aaagaacttg taagtataaa gactgaagat gttggtcatg
    22561 gaatactagg tggatttgaa aaagaaggac aggaatatat tgaaaaactt gcaaattaca
    22621 taggttttag tgtagataga caagaaatga gcgaagaatt aattaaaaaa gcaaaaaata
    22681 tatataaaga aggaaatcta ggtcacaatt atcaagatag atataattta atttgtaagt
    22741 atagtgatga tttacctggt aagacaattg tatttaatgg tcatgtagac actatgccac
    22801 caggtgatat aagtaagtgg aaatataatc catatcgtgc tacagaagat aatggaaaac
    22861 tttatggtct tggaactgct gatatgaaat ctggacttat agcatcaata ttagctgtaa
    22921 agcttataaa agatagtggt ctaaatgtac ctggtaatgt aaaaataatg tcagtagtag
    22981 atgaagaagg tggcggaaat ggtaccataa atgcagttat gaatggtatt ggtggagatt
    23041 gttgcataat ttgtgaacca tcagaacaaa acttaatagt tgcacatatg ggatttgtat
    23101 tctttgaagt tgaggttaaa ggtgtgtctc ttcactgtgg tagtaagtgg gagggtgtaa
    23161 atgcaattga gaaggctatg ttgttgcttc aagatataaa agagttggaa cataactggc
    23221 ttatgatata taagcatcca ctattacctt cacctacaat aaatttaggt gtaataaatg
    23281 gtggaacagc aggttctact gtgccagata agtgtgtatt taatttatgt gtacacttct
    23341 tgccaaatat aatgagttat gaacaagttg taaatgatgt aacaaatgtc ataatgacaa
    23401 gggctaatgg agatttatgg cttaaagata ataaaccaaa tataaacata tatcaatcag
    23461 ggttaggttt tcagatggac aaggattctg attttgtagt gaatgcacat aaaatactag
    23521 aagaaacttt aggaaaaaaa ttagagataa aaggttcaac agctggcaat gatgcgagat
    23581 taatgaaaaa tttagctgaa ataccaacac ttatattagg gccaggttca atagaacaat
    23641 gtcattcaat tgatgaatat gttgaaatta aggagtattt agatagtata cttatgtatg
    23701 caagtctaat attaaactta taaaagtagg aggaatatat aaatgaaaaa agtattaata
    23761 gtaggggaat cttgggtaaa aaatataact catataaaag gatttgatac gtttgttaca
    23821 actcattatg aagaagctgt aaagtggttg aaagaagcaa tagaatctgg aggatatgag
    23881 acagttcata tgcctgcaca tgtagcagca gatagttttc cgtataaatt agaagagtta
    23941 aatgagtatg actgtataat attatctgat ataggttcta atacgttctt attatctaat
    24001 agtactttta tagattgcaa tagtaatcca gatagacttg aactaatcaa agagtatgta
    24061 aataatggtg gggcgttaat catggtaggt ggatatatgt catttacagg aatagatgca
    24121 aaagctagat ttggagaaac tgctatcaaa gatgtattac caataacaat gatagataaa
    24181 gatgatagag ttgaaaaacc agcaggaata attccagaag ttattgactc tgaacatcca
    24241 gtattaaaag gtataccaac agaatggcca aagtttttag gatataacaa aacagtagct
    24301 agagataatt gtcctgtttt agcaactatt ggaggagacc catttgtagc tgttggcgag
    24361 tttggaaaag gaaaatctgc tatctttagt tctgactgtg cacctcactg gggtccaaaa
    24421 gaatttactg attggaaata ctataataaa ttatgggtta atatgcttga ttggttaaca
    24481 tgctaaaaat tttataaaac ttgaaaacct cttacttgat aaaatgaaac ttacaagtca
    24541 agaggtttta ttgtataaaa tggttgtatg gtagaaaata tttttaaatc agttaaaatt
    24601 agtcattttg gctgataatc gataagttat tagaaacagg gaggtttata taattaatat
    24661 ggataattta aataaaaagt ttttgatgga atatatagat gagatacagg gagaattaag
    24721 agatatatca gataagatat ggaaaaatcc agaacttcag tataaagaat actatgcttc
    24781 aaatttacaa aaagaatgtt taaaaaaaca tggttttagt atagagggat tagaaggtat
    24841 ggatacagca tttgtggcta gttatggaga aggtagacca gttatagcag ttttgggaga
    24901 atatgatgct ttagatggtt tgtctcaaaa agtatccact actaaagaac ctattgtaga
    24961 tggtggtgca ggtcatggat gtggacataa cttacttggt acaggttcaa taggagctgt
    25021 aattgcagta aaggaattaa tcaaactaaa aaagctgaaa gggactataa aatactatgg
    25081 atgtccagca gaagaagatt tatctggaaa agtattgatg ataaaaaaag gtttttttga
    25141 tggaattgat tgtgctttta gttggcatcc atttgatata aatactccga taagaatccc
    25201 aacacttgct aattactctg tgaaatttag atataatggg attagtgctc atgcagcaca
    25261 agctccttat aacggaagaa gtgcacttga tgcagtagaa cttatgaata taggttgtaa
    25321 ttatttgaga gaacatatat ttgataattg tagagtacac tatgtaacta ctaatggtgg
    25381 aaaaatgcca aatatagttc ctgattttgc agaagtgtgg tattacataa gaggagttaa
    25441 aatggagcat gtaagagatg tatttggtag gattgttgat atagcaaaag gagcagcatt
    25501 aatgactggt actattatgg aatatgacat tataagtgga gtatatgact atattccaaa
    25561 tacaatatta acagatattc tatcacaaaa tatgaaatta gtaggtgtgc aaaactataa
    25621 tgaagatgac tactattttg cagataaatt agctgagaca gtgtctatag ataaaagaag
    25681 tagtgtttct agtgtattaa gtggaaataa ggatattact aagatgaatt tacatgatga
    25741 ggttacagat gatacattta ctcataataa ctgtatatca ttatcattgg atattggaga
    25801 tgttagctac ataattccta cagcacaatg ttcttgttca gtttggccta ttggtatttc
    25861 tgcccataca tggcaatctt gtgccagtgc aggttctgat atgggattta aggcaatgtt
    25921 attggcatct aaatctatat catgttcaat aaatgatgta atgcttgatg aattggttat
    25981 aaataaagca aaaaaagaat tgaaggatac tgtaggtagt tttgaatata ctccaattat
    26041 ttgaagagta atttaataca agtaagattg aattgtatga attaggatga atatataaat
    26101 taatattatt tttaacttaa ctttctaatt attttcaatc taagatacaa taattagaat
    26161 atatttttaa agtttcctat ttaaggaaaa taatttgatt ttatgtttga taaaaggact
    26221 tataatttgt aagccctttt attatattta ttttttgttt ataattaatt ttatttttta
    26281 ggtttagtta ggttatagat taccctgaaa aataacattt aacttattat taaaaacatg
    26341 taagaatagt ttataaatat tttattttcg atgttgttta ttatatccat tttatcgatg
    26401 gatgaggaat ggctctgcct tccctagtta cagatgtagt agggaaacca attgcacagg
    26461 catcaaatcc atattcacct gttggtactc ctaaaatatc acaaaaatct ttattatcgc
    26521 tcaatcttcc tattacacta acaagttcaa aacctaatcc taaagcagtt gatttaagcc
    26581 acatattctg catcacatga gataatgact tttgttctat aggtggtatt ccacgacgtt
    26641 ctgccacaat aataagataa ggtgctgttc ctataccaag aacccctttt tcaacttgca
    26701 tttttaagga agtaatgaag gattgaaggg taatgttgtt ctttgccttc ttctcattga
    26761 ctgatatttg agttttaata acatcaacaa gaatggtttt tattttattc atttgtaaac
    26821 tgttatttga aataacaaag aaatgtctga aatctgtttg ttttgctact gaaagtattg
    26881 cataaggtgc aagtcttcca gtttcaatta tttcttcaat cagccctttt gaaggtactt
    26941 cttttgtaaa acttcttatg gatcttctag ttcttaatag catatccaaa acttcattaa
    27001 cattgttttt atctaaattg ttcattttta tcctccacta atagtattct taagatgttc
    27061 tataatgcat ccatataaag gcgaactttt cggtcatatt aaacatttcc ttcaaattaa
    27121 gtcgctattt ctatgaacac aatgttgatt aataatctat atgtatatta taatatttat
    27181 attgcattat gcaataaaca ataatattta aactgttaag taataaacat ttactataaa
    27241 attgttaatt aaaattaaaa aaatttatat ggaatgagga aataattcat gaaaaaagta
    27301 tctattgata gaagaactat acgtactaaa aaaatgatta ggtctgcatt agcagagtta
    27361 atagatgaga aaggatttaa caatatatca gttactgatt taactcaaag ggcagatata
    27421 aatagaggaa ccttctatct gcattatgtt gataagtatg acttgttaga gaggattgaa
    27481 aatgaaataa tacaggaaat tgaagaggag accaaacatc ttgattcatc caacatgatg
    27541 gagatagata cctcaagtga acctcttcca tttatggtaa agctttttga atattttaga
    27601 aaaaattcag taattattaa atctatcttg ggtcccaaag gtgaccctac ttttgaaaga
    27661 aaaataaaaa aatttattga aaccaatttg tttgagaaac aaaaactaat aaattttaac
    27721 atagatgagg caataatttc agaagaatat tttatacaat atatactttc agcagactta
    27781 ggtgtaattc aatattggct tgaaaaaaat atgaaagagt cccctgaaga aatggcactg
    27841 atacttgcta gaatgtcgtt actcggtccg ttaagagcag tgggaattcg taaagattca
    27901 taaaaatagt tttatatata ttagactttg aaaatatatg tttaaaaacc attttttact
    27961 actactgttt ataaattagg ggagatatct taaaatatta gtaaaaggag tgctaagtga
    28021 gtgtaataac tatgagataa gaggtttagt tgatatagtc aaaacttcaa aagaatcaat
    28081 tagaaaagtt aaaatattgc aattaaattt aaaggagtaa tatatgaaaa atgaaaatat
    28141 aagttatttg gcgttaggat tatgttttgg tgttgttttg ggttcattat ttaaaaactt
    28201 agctattggt ttatcctttg gattagttat tggagtagta ttagacagta agaaaaataa
    28261 ataaaacttc aatagtaaca tataacaatt atactatttt tgtataaaat cattggaaat
    28321 caacaataga aaatatttgt tatttaaaaa ctaaaaatac agtttaaacg acctaaaaat
    28381 atattatata attattataa caagataagt gagagtaagg ttatgataat agagtaatat
    28441 ttttcaatta ttactctatt tatatttatt tagttatact atagtttata ttgttatttt
    28501 attttcatat gcagtatagg gaatggatta ccttgttcat cgaactcaga ttttttaaag
    28561 actttaaatc ccatatgttt ataaaagcct aatgcttgtt gattttgctc attcacatct
    28621 acataattta catttaatac ttctattgca tattctacaa gtctttttcc aattccattt
    28681 cctatactat aattacttac aaataacatt tcaattttaa aatcatgtat tcccataaaa
    28741 gcttttataa tacctttttt tgtctcttac acataaaaaa ttactaacat atttagcaca
    28801 ttctttaact tgaggcttta ttgatattat attttcttca cttaaaaagt catgtgttgc
    28861 tcttactgat gattcccgtg tatctagtat ttctttcata tctttattgt taataatatt
    28921 taaattttca atttttatca tttaataatt cctcttaagt aagtatgtta cttaatatta
    28981 tatgttaaat atgatttaaa aaggttataa gaatattttt gtattaaata taatcaaata
    29041 aatatattta tttgtcataa attaaatgtc cactaaaata gaaaaaataa gaagaaatag
    29101 gtaataaatg atagcttata gcaaaataaa gatgtaagta taacaataga tgagattgga
    29161 attaagtcac tatacctaac agaacattct taggcgaata tagaagactt aaaaaagaaa
    29221 agagaagtag acaagaattt attaatgatt acatataaaa taaatgaatt ataattttat
    29281 taatgatata ataataatta acaaaaaata aaagaggaac gagttaatgt ttgatggcat
    29341 acactcattt tctaaccaat aaaacaatag attcaattaa ggttactaaa gtctaatcaa
    29401 cacataaaca tataggataa atacatcttt ttaatatatt aattatgtta gacttacaaa
    29461 aaatgtaaat acatagcttg ttaaatcttg attgaacctt aagtaataag ggataaaaaa
    29521 tgacttgttc aaaggcaaag aatatactat taaatgatat aagtaactta gagataatat
    29581 gtagtaagtc aaaagaacta tatagcatca gtaagtaaaa agcgtaaaaa cttacataat
    29641 gcactataaa ataaatgagt tagaaaataa atataattta tataataaag tagtacaaaa
    29701 aggagtattt atgtttggat atgttaaaat aaacaaaatg gatttaacat ttagagaata
    29761 tgattattac aaagcttact attgtggact atgtaaatac ttaaaaagaa atcatggaga
    29821 aatctctagg ttttctttga attatgatat aacattttta attgttttat taacagcagt
    29881 atataaccca gagtctataa gtacagagga agtgtgtata gtaaatccat ttaaaaagaa
    29941 aaaggtaatt acaaatgata ttacagaata tgcagcaagt atgaatattc ttttaacgta
    30001 ttataaattg gaagataatt taatggatga taaacgcata aaagataaat tggcatatta
    30061 tatatataaa aacaaattaa aattagcata tgaaaagtat cctgaaaaag cagagtatat
    30121 aaaacaacaa ctaaatgaat taaataagtt agaaaaagat aaaaatataa atatagatga
    30181 agtatctagt atatttggaa atataatggg tgaagtattt gtctataaaa aagatgaaaa
    30241 tgagagaaac ttaagaatga taggttttaa tataggtaag tatatatatc tactagatgc
    30301 ctatgaagat ttagatgaag attttaagaa aggaagatat aatccattta tagagtatat
    30361 tgataaaaat gatgagttaa aagaaaaagt aaaaaaaata atagtaacat cattaggatt
    30421 tttagctagg ggaattgata atctaaatct aaataaaaat gttggaataa tagaaaatat
    30481 aatttattct ggtgtttatt taagatatat taatatatta gaaagtagag gtggaaagaa
    30541 tgtacagtaa tacttataat aatgaaaatt ttatgagagc aagagcattc atagaaaata
    30601 gtgaatttaa aaaagcatat gattttttaa aaactttgac tgacaaatgt gcagagtggt
    30661 attatttaac tggcttttct gcaatgaaca taggatatta tgaagaaggt gaagacttct
    30721 taaaaagagc aaaatttatg gagcctgaaa atagtgaata tagtgatgca cttagaagtt
    30781 atacacaata tagaaatgat tatagcaata gggctgacaa ttataataga agaagacgta
    30841 atgatttaga tggatgttgt tgctgttgct gtgatgattg ctgttgttgt ctaggtgacg
    30901 attgttgtga aaattgtgct aagctttggt gtttagattc atgttgtgaa tgttttggtg
    30961 gagatttaat aacttgttgt taggatgata aatatgagta taaaagttgc ttatggagga
    31021 gttttattag cattaaatgt gatattgttg actcttacaa atattattcc tgtaaataca
    31081 ttgtttatta tggggttagc atcactttta gtatcaattg taataatgga atggggcttt
    31141 aagagtggaa tcgcttttta tataggttct atagttttag gatttatagt gatggcaagt
    31201 aagtctcaat ggattgtata ttcacttacc tttggaatat atggtattgt aaaatatctt
    31261 atagaaaaag ataggtctat atatattgag tattttatga aattagtatt tgcaaatata
    31321 atgatactta tattgtattt tttattaaga acaatagttt atattccaat aaacatattt
    31381 attataggtt catttgagat agcctttata gtatatgact atgtttacag ttcttttata
    31441 ggttattaca ataataggtt aagaaagatg ctatttaaaa aataatagtt gatttttata
    31501 tttaatttta atgaaattgt agtttggata agtgtaaatg atatatctga atatacatta
    31561 aagcataaag ctaaatttaa tatattctta gtgcaacata taaaagcttt gatttttagt
    31621 caaagctttt atatgttaga tataaatatt agatataata taagttttta aaatagatag
    31681 tataaattaa atatccacta tatttacatc tgtagataga gaataaataa tatcttttct
    31741 ttctactatt atctcaacat ttttagaaat ttcctcatca agtgatattt gagataaaag
    31801 ttcctttgtt ggatttattg ctattggatt tccaactctt tttagcatat ttatatcacc
    31861 attagtatct ccataggcat acgagtttga taaatctaaa tcatacttta caacaaaatc
    31921 atttatagca ttattcttac ttatagaatc ccacattgga ataactgtgc ctgtaaatat
    31981 attattttca aagacataat cacttcctag aaaatcggtt acattatatt tttttgccat
    32041 tttttcaaca agaaatccag ggctaccaga tataaatata actatgtgtc cttgatttag
    32101 atgccactca atccttgaac gtgtgtattt ataaactcta tctgctttta atttaattac
    32161 ttggtcactt gtaaagttga tacaggtttt atctaatcct tttagtgaat caacataaag
    32221 gtcacatatt tctaatagat aatcatcata attaccttgt cttttatccc aatccataaa
    32281 agtgtctcta gcatgtttat accaattttt ttggtcaatt atatcgtatt taattaattt
    32341 tttaaaatgt tcaaccataa gagagtctct ataaagagta ccatctatat caaaaaaagc
    32401 tgctatattt ttcataagac cacctcaatt aatcatttcc ttatattata ttataaattg
    32461 tatctaagtt gttaaaatat atgtataata atttatatat taaaaaacaa gtattttaga
    32521 gtttaaagga tgtgactata tgaattttaa ttttgcaaag gctacaaatt ctagacttat
    32581 gggcagttta ggtcttataa taaattggat agatgatgaa aacaatcact tttgtcaata
    32641 ttttttatta gatgcagagg gattaggatt agcagattat gtgagtttaa ataacccaac
    32701 acaagaagaa gcttatatgg aagaagaaag attgatggga ggatttggtt cagatagagt
    32761 tgaattaacg aaggatgaat ctttattttt agtatcttat tttggtaata agaatcttta
    32821 ttatgataag ctattgccag gagataaatg tgagtatatt gatattataa aaaactataa
    32881 aacagattta attatagaaa aattatacaa taaaatatgt aaaagagttg atgaggaagt
    32941 tgaatttata aactatatga ctatgagatt tatagcatgg gatagagaaa gtttaaaata
    33001 tttttctgga agtgacgaga ttgcaaatat gcatattact aatataaatg gaacattact
    33061 taaaaacgtg gtaagtgata aaggtcaagg cagatatata agtgaagctt tatatgaaga
    33121 caatgatgga tattatatat gtaaaattgc tttttgcata agtaagtgct atgaaactgg
    33181 ttttagaatt aattctctat tagtgacaga taaagaactt atgtatgatt ttgaggtatt
    33241 tgatgagatt tctaaaagtg aatttgtaag tgtttacagt gtaaattcac ctgaagaatt
    33301 tgcaggagta ttttatagag aaaatccatt tctgttaaaa agtaatatga atgaaggtat
    33361 attttttact agatttaatt ttaataatga ccatgtaaaa gaaaatgtat atataataaa
    33421 caatgatatg aaagctatat attacttaat gggaaataag ttttttattg gtacttataa
    33481 cgaaaatgat tgcaattata tcaatgaaat aagtcagtct aattatagtg actatattaa
    33541 atttgaagag aaatttttct ttgagcaaaa tgcattatat gactttgcag aatcaggttc
    33601 attagatttt gatgattttt tggaataata aatttagaca ttatttaagc gagattaact
    33661 gaatttaatc tcgcttaaat ttatttctat aatattgggg gaatattatg aggaatacat
    33721 ttattattgt ggtcaattat taaaatttta tacagtttat tataaaaaat ttatactttt
    33781 ctttatgttg tttgccaata ttagtctcaa atacgagtac catactattc tgacccacca
    33841 acacaagaaa gagtttttta aatgaaaaag tcagataaaa ttaaatttta tctgactttt
    33901 tctatgttta tcttattaga ttatgttaat atctgttgac cgaataagcg catactcagt
    33961 caactttcta tacctataat aatattgggg gaatattatg aggaatacat ttattattat
    34021 ggtcaattat taatgtttta tacaacttgc tcaaaaaaat atatattaca tttcttcctc
    34081 atcaaattct tcaatattag tagcctgtgg tataccttgt atagacatat tactagaacc
    34141 ataaggagta ggatatatat taggaggcat agtactaggc ataactacag gcataccttg
    34201 cattgtatta tgacatataa ctcctggtat catcataagt acattaggag gcatattttg
    34261 attacatgag aagttaggaa tacccatagt attattcata ttatacccca tattactgtt
    34321 catgttatta ggcacattgt taggcatacc catgttacta ttcatattat taggcatatt
    34381 gttaggcata cccatgttac tattcatatt attaggcata ttgttaggca tacccatgtt
    34441 actattcatg ttattaggca tattgttagg catacccata ttactattca tattgttaga
    34501 catattgtta ggcataccca tgttactatt catgttatta ggcatattgt taggcatacc
    34561 catattacta ttcatattgt tagacatatt attaggcata cccgtattat tattcatgtt
    34621 attaggcata ttatttgtag cagatgtatt gtaattcata tttccggatg tattatttgt
    34681 gttaggcaag ttgtttggag aattactact tttaggataa tgatttacat tattaggata
    34741 taggttattt atgttctggt tattaggtat ttttgtataa ccattagaaa tttgagggtc
    34801 atttctcaat tcatcttggg gaatttcttc attagtaata taatctgcat agttcgctgg
    34861 gtctaagtaa ggcatgtaac tagtatctaa atcctttttt ttcttgttac tcatattaaa
    34921 cttgcacctc ctagaaaact ataaaaaagt ttacaaaaac ttattctaat aatatatata
    34981 ttaaaaaagt ttataatatg tgcattctaa ttatattaaa ttaataaaaa ttattgttgc
    35041 aaatttagga atgatagcat ataatgaaca tatgaacagt tattcatata ttaaaacaat
    35101 ggaggattaa agatgagaga agagataaat gattgtaatt gtaatatagt acatgaagaa
    35161 atagtaacag aggctaaatc aactatgcca gatgaagaga tgttatatga tttagcagaa
    35221 ttatttaaag tatttgggga tactactaga gtaaagatat tatatgcatt atttgcaaat
    35281 gaaatgtgtg tatgtgatat agcgagttta ttaaatatga ctcactctgc aatatctcat
    35341 caacttagag tactaaagca ggctagatta gtaaagttta gaagagaagg aaaaacagtg
    35401 tattactcat tagatgatag tcatataagc cagatatttg attgtggatt aaatcatatt
    35461 agagaaactt ataaatgata aatgagagga gtgaatatat atggaagcaa ataatttaat
    35521 taaaaaagaa tttatactag gaggattaaa ctgtgcacat tgtgcagagg agattaataa
    35581 taaagtttct aaactacaag aagttaaatc ttccaactta aattttataa ataaaaaact
    35641 tatagtaaat ataaaggaaa gctttaatga ggatactact atagaaaaga taatagatat
    35701 aatagattca acagaaccag gtcttgatat acaaataagt tctaaagaaa atgcatctag
    35761 taaaacatca attaaaaaag agcttatatt aggaggatta aactgtgcac attgtgcaga
    35821 ggagattaat aacaaggttt ctaaattaaa agaagttgaa tcttctaatt taaactttgt
    35881 aaataaaaaa cttacagtaa atataagtaa taactttaaa gaggatgatg ttataaataa
    35941 aataaaagaa ataataaatt caacagagcc aggacttgat atacaagtag ggtctactga
    36001 caaagtaaaa gggagaacta ctgaaaaatc aggagctgta aatgatacaa ataagaaaga
    36061 attagttcca cttataattg gagcacttgt atatatattt ggtatatatc aaacagctac
    36121 aggttatgaa agtcagttta gcaatatagt atttatagtt gcctatgtaa tagtaggtgg
    36181 cgatgtgctt ttaagagcaa taagaaatat atcaaaagga agagtatttg atgagaactt
    36241 tttgatggct ctagcaacag taggagcatt aacaataggg gagtcatcag aagcagtagg
    36301 ggttatgctt ttctataaag taggagagta tttacaaggt gttgcagttg gtaaatccag
    36361 aaagtctata acttcactta tgcaaataag accagattat gcaaatctaa aatttaattc
    36421 tgaagttaag gtagtgtcac cagaagaagt aaatgtaggg gatataatag tagtaaaacc
    36481 tggtgaaaaa gtaccattag atggtgtagt agtggatgga gtttctatgc tagatacttc
    36541 tgcactcaca ggagagtcag tgctgagaga agttgaaaaa ggagatgaaa tcttatcagg
    36601 tgttataaat aaaaatgctt tattgagtat tgaagttaca aagagttttg gagaatcaac
    36661 agtttctaag attcttgacc ttgttgaaaa ttctagcatt aaaaaatcaa agacagaaaa
    36721 ctttatatct aagttttcaa gatactatac tccaatagta gtaatagctg ctttattaat
    36781 agcatttgtg ccaccacttg taatctcagg tgaggtattt agtgattggt tatatagagg
    36841 attgatattc ttagtcgttt cttgcccttg tgcattagtt ttatcaatac cacttagttt
    36901 ctttagtgga attgggtttg catctaaaaa tggtatcctt attaaaggaa gtaactattt
    36961 agaagcttta agaagtgtag atacagtagt atttgataaa acaggaacac ttactaaagg
    37021 tgtgttcaat gtaactaagt taaatcctga aggtatatca gaagaagaat tattagaata
    37081 tgcagctatt gcggaggtaa attcaaatca tccaatagca aagtctatat taagttacta
    37141 taataaaaaa attgatttag atacaataga cagttatgag gaaatagcag cttatggaat
    37201 tagagtaaag cataatggca attttatatt agcaggtaat gagaaactta tgaaaaaaga
    37261 aaatatatct tattcatcag ctaaagaagt aggcacagta gtctatattg ctgttgataa
    37321 agtatataga ggttatatag ttatatctga tgaagtaaaa gaagatagta aaaatgccat
    37381 aagaagctta aaagcaatag gggtaaaaga agttgtaatg ttaactggag ataatgagaa
    37441 agtagcaaaa aatattgctc aagaattaga attggataca gtttactcaa atttacttcc
    37501 taatgaaaag gtagatagat tagaagattt atatgaagga agaactgaaa aagagaaaat
    37561 agcatttgta ggtgatggaa taaatgatgc tccagtatta gctcgtgctg atgttggtat
    37621 agctatggga ggcttaggtt cagatgctgc tattgaagct gcagatgtag tgcttatgac
    37681 agatgagcct agcaagatat ctaaagcaat tgaaatagca aacaagacta ataagatagt
    37741 gtggcaaaac ataatatttg ctctaggagt aaaaattata gttatgatac taggtgctgg
    37801 aggagtagct actatgtggg aagctatatt tgctgatgta ggtgtggcac ttatagcagt
    37861 agtaaatgct atgagagcta tgagataagg gataaatgta aatccatact atttaaaaaa
    37921 cttataatta tatattgaag tatgtaataa tgaaaggtat caataagttt cttttaactt
    37981 tattggtacc tttttattgg agcgctttgc atatataaat ttatattcat tatccattgt
    38041 gtttatttaa tgtatttatt tagtgtagag cttttatatt gtaattttaa aatttagaca
    38101 tagaaggttt attaataagt ctatattaag tttaaattag attcataaaa attataatac
    38161 ttatgattgt atatatatta tattaatagt tataattttt acaacaaaat gtgtgtgtta
    38221 aaatactcta aaccaacagt atgactgtca ttcaataaat tatgtaatat aagaaagtaa
    38281 atatttttaa aaaataattt aaaaaagtat tgacgaaata tttttaag
//
LOCUS       DAMJWO010000037        37944 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.038, whole genome shotgun sequence.
ACCESSION   DAMJWO010000037 DAMJWO010000000
VERSION     DAMJWO010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37944
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.038"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            87..1781
                     /locus_tag="PC366_001886"
     CDS             87..1781
                     /locus_tag="PC366_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HDF2577414.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLSCVEDINNSRNYKEQQKNIHKIN
                     LLRNKIETLSNIASIRYSTDTFNKFYKEEKNYWDEYMPLYEELNSHFYNAIVNSKFKY
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGNIRNLS
                     GMGKFMYSKNRKTRELANKAYYNFFEENETKFDDIFDKLVKLRDKISKKLGFEDFVEL
                     GYVRMMRSDYREDMIKNVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIQNGKRMYSELSKETNEFFDFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSSIKFIPYGVIVDEFQHYIYKNPNVDKSKRKEIWR
                     FLEKKYLPHRKYGDNSFLERGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DAGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
     regulatory      2113..2223
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            2327..2698
                     /locus_tag="PC366_001887"
     CDS             2327..2698
                     /locus_tag="PC366_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HDF2577415.1"
                     /translation="MIIITNNPKVKEEVQGREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVILKKGNRLDINSLTLIEEAIITASKFQDNKKTPKWTENVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            2794..3741
                     /gene="trxB"
                     /locus_tag="PC366_001888"
     CDS             2794..3741
                     /gene="trxB"
                     /locus_tag="PC366_001888"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDF2577416.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            3826..4143
                     /locus_tag="PC366_001889"
     CDS             3826..4143
                     /locus_tag="PC366_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HDF2577417.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
     gene            4412..5698
                     /locus_tag="PC366_001890"
     CDS             4412..5698
                     /locus_tag="PC366_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HDF2577418.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            5810..6283
                     /locus_tag="PC366_001891"
     CDS             5810..6283
                     /locus_tag="PC366_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:5942..5944,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HDF2577419.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            6315..7625
                     /gene="grdB"
                     /locus_tag="PC366_001892"
     CDS             6315..7625
                     /gene="grdB"
                     /locus_tag="PC366_001892"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:7362..7364,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HDF2577420.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            7882..9414
                     /locus_tag="PC366_001893"
     CDS             7882..9414
                     /locus_tag="PC366_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014520415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III family protein"
                     /protein_id="HDF2577421.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNSDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIAGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            9425..10570
                     /locus_tag="PC366_001894"
     CDS             9425..10570
                     /locus_tag="PC366_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase"
                     /protein_id="HDF2577422.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFDDIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            10880..11959
                     /locus_tag="PC366_001895"
     CDS             10880..11959
                     /locus_tag="PC366_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2577423.1"
                     /translation="MSRVKNVVGLLGTKGVDALYLTKKTNVNYISGFPDEEAYAVICK
                     DGNFLVTDSRYMELAEKVCKDFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            12072..12671
                     /locus_tag="PC366_001896"
     CDS             12072..12671
                     /locus_tag="PC366_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577424.1"
                     /translation="MYKKHKFIKNIKKAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSANFIKRPLRKYTNTDVSSNLFIDNNLPPKGQE
                     SSQNNIMNVKNTIGFTSEADNYEKKIPINNNEGFEEGETSELQIIIATVICIAALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSKPD"
     gene            complement(12858..13730)
                     /locus_tag="PC366_001897"
     CDS             complement(12858..13730)
                     /locus_tag="PC366_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2577425.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISNYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTENLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIEYMASIHIN"
     gene            14147..15550
                     /locus_tag="PC366_001898"
     CDS             14147..15550
                     /locus_tag="PC366_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577426.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISSDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASIKDKKEILKVVDPEGKLDVNTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVVNFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            15577..17121
                     /locus_tag="PC366_001899"
     CDS             15577..17121
                     /locus_tag="PC366_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HDF2577427.1"
                     /translation="MNNEGAFEELSGRLRNKELCDLIMNADEAAKIIEDGMVIGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEEGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGVVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKAGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            17152..18543
                     /locus_tag="PC366_001900"
     CDS             17152..18543
                     /locus_tag="PC366_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HDF2577428.1"
                     /translation="MEKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKVAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKVQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            18736..20232
                     /gene="abfD"
                     /locus_tag="PC366_001901"
     CDS             18736..20232
                     /gene="abfD"
                     /locus_tag="PC366_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HDF2577429.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKKIAGIKKEEALNL"
     gene            20367..20642
                     /locus_tag="PC366_001902"
     CDS             20367..20642
                     /locus_tag="PC366_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577430.1"
                     /translation="MTCGVRFCGGCNPRYERGKALTIIKEHFNGRVDFSIAQENVEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            20666..21973
                     /locus_tag="PC366_001903"
     CDS             20666..21973
                     /locus_tag="PC366_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HDF2577431.1"
                     /translation="MSWQELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPAFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSEFDYIVEKSQPLFELQPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFANNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVRESLAVEFEKRFKEKY"
     gene            21993..23111
                     /locus_tag="PC366_001904"
     CDS             21993..23111
                     /locus_tag="PC366_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HDF2577432.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVSPKKVKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     SQIDEFTDSTIANQQRLLANNYVELSREEIREIFANLY"
     gene            23398..24318
                     /locus_tag="PC366_001905"
     CDS             23398..24318
                     /locus_tag="PC366_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HDF2577433.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILPIQVCAVFLLIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFIPPRYEDVAYEVKEEEK
                     TDESNEVDTIINKGMNYLTQIKEANKNIKSESMGDKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            24433..25590
                     /locus_tag="PC366_001906"
     CDS             24433..25590
                     /locus_tag="PC366_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDF2577434.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTNDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(25675..27174)
                     /locus_tag="PC366_001907"
     CDS             complement(25675..27174)
                     /locus_tag="PC366_001907"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HDF2577435.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIENEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
     gene            27770..29194
                     /locus_tag="PC366_001908"
     CDS             27770..29194
                     /locus_tag="PC366_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HDF2577436.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWVIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TMAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANQSEEDSTSLEEAKAKMSDMKSASKNSEKNIEEKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLNIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDALFKRLESK"
     gene            29229..31358
                     /locus_tag="PC366_001909"
     CDS             29229..31358
                     /locus_tag="PC366_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDF2577437.1"
                     /translation="MKKKKITSRQKKIILMIVENSKKNIPITISEIAGTLELSSRTVL
                     RDMSGIEKWFDENDFNFVKKPGVGLILEENIENQNFIIELLEEEKIEKEYSKEERNLI
                     ILSKLLVSNEPVKSYYFAKILKVSEGVLNNDFALASKWLERFDIELVRKPGLGVYLKG
                     QEKNFREAYVNLIYDSFNEKEILDMVRNISENIQTDKAIEILSENRLLNLMDRCIIRK
                     VEATLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITEEFK
                     LAKEIVKGMETDFNMDIPVDEVGYITMHIRGAKQRSSSNHKALNLDDIEIMEITNKMI
                     DLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYAYDGVE
                     KISRIIKDKLNINSIPESEIGYIAMHFASAIEKNLMMNTNINIVVACPTGIGTSRFLS
                     TKIENKFPNLNILETISAINIDEEYLKEKDVDLIVSTVELNTSLNYICVGPFMSLDDE
                     QIIKEKIKSIAQNKLINLNAKNDTKSKNKVYEQITESMNIGKDILQFLEEIRFEKFES
                     KDLSELIEDSSKIFAKSSEDIISIKESLKERLKISIPYIEESKILLLHCMSERIDIMK
                     LSIIKLENRIVLDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKINKF
                     SIEEMTLEVKDIVFNFYTNRLKAFIDK"
     gene            31388..31810
                     /locus_tag="PC366_001910"
     CDS             31388..31810
                     /locus_tag="PC366_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2577438.1"
                     /translation="MSKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAN"
     gene            31829..32980
                     /locus_tag="PC366_001911"
     CDS             31829..32980
                     /locus_tag="PC366_001911"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF2577439.1"
                     /translation="MKKAIQFGAGNIGRGFIGSLLVKSGYHVVFADVNEEILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVQAEIITTAVGPLVLTKIASTIAK
                     GIKARKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEMYVGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFICDIVKSAMVESGEGLIKKYNFDSEVHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYGLSVDNLILGIGAALHYN
                     NSEDTQSVELQELIKSIGVKKAVAKIANISNDEEILNNIEKSYIFMKNL"
     regulatory      33086..33187
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            33370..33942
                     /locus_tag="PC366_001912"
     CDS             33370..33942
                     /locus_tag="PC366_001912"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDF2577440.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFKGEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANDVRLESLAVVESIDNGTVKFR"
     gene            34006..34656
                     /gene="fsa"
                     /locus_tag="PC366_001913"
     CDS             34006..34656
                     /gene="fsa"
                     /locus_tag="PC366_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDF2577441.1"
                     /translation="MRFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHKGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGAFLKL"
     gene            34808..37732
                     /locus_tag="PC366_001914"
     CDS             34808..37732
                     /locus_tag="PC366_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2577442.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKI
                     GIKDKDPASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCKNEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSRIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTLG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKEHIEKQIKEYGTLIEVKPVAFLNNNLEEELNDIEAEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPALNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVIKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
BASE COUNT        15007 a         4150 c         7127 g        11660 t
ORIGIN      
        1 taataattta taaaaaagta ttacatagta catgtaaatc tatatttata aatacaataa
       61 agtaaagttg taaaggagtg ctttaaatga agttttcaga gtttaagtat gaaagaccca
      121 attataatag tatgaaaaaa gagtttttga gttgtgtaga agatataaat aattctcgta
      181 attataaaga gcaacaaaaa aatatacata agattaattt attaagaaat aaaatagaaa
      241 cgttgtcaaa tatagcttcg ataagatata gtacagacac atttaataaa ttctacaaag
      301 aagaaaaaaa ttattgggat gaatatatgc ctttgtatga agaattaaat tcacattttt
      361 ataatgctat tgtaaattca aaatttaaat atgatttgat aaaagagttt ggagaacaat
      421 ttttcacaat agtagagtat tctttaaaaa gtttttctaa agaaataata agtgaattgc
      481 aggaagaaaa taaattgtgt tcagagtata ctagactttt agcttcagct gagataatgt
      541 ttgatgggaa tataagaaat ttatctggta tggggaaatt catgtattct aagaatagaa
      601 aaacaagaga attagcaaac aaagcatatt ataatttctt tgaagaaaat gaaactaaat
      661 ttgatgacat atttgataaa ttggttaaac ttagagataa gatatctaaa aaactaggtt
      721 ttgaagattt tgtagagctt gggtacgtta gaatgatgag aagtgactac agagaagata
      781 tgataaaaaa tgttagaaaa caagtattaa aatatgttgt tccaatggcc aatgagcttt
      841 atgaaaaaca agctaaaaga attggtctag aatatttaag ttacatagat gaaggcgtgg
      901 aatttttaac aggaaatgca agtttaaagg gagattcaag atacataatt caaaatggta
      961 aaaggatgta ttctgaactg tcaaaagaaa caaatgaatt ttttgatttt atgttagaaa
     1021 atgaacttat ggatttagaa acgaaaaaag gaaaaggagc tggagggtat tgtacttata
     1081 taccagatta taagtcacca ttcatttttt ctaattttaa tcaaactgct gatgatatag
     1141 atgtgttaac acatgaggca ggacatgcat ttcagttgta tatgtctaga tggattgata
     1201 tgccagaaat taattttcca acgcttgata gttgtgaaat ccattcaatg agtatggaat
     1261 ttataacatg gccgtggatg gatttatttt ttaaagaaga tacagataag tacaaattca
     1321 ctcacttatc atcttcaatt aaatttatac cttatggagt aattgttgat gaatttcaac
     1381 actatattta caaaaatcct aatgtagata agtcaaaacg aaaagaaatc tggagatttt
     1441 tagagaaaaa atacttacct catagaaaat atggtgataa ttctttttta gagagaggtt
     1501 gttggtggtt taaacaagga catatattta aaaatccgtt ttattatata gattatgtat
     1561 tagctcaaat ttgtgcgtta caattttgga aaaaaatgat tcaagataga gatgcaggat
     1621 ggaaagatta tataaatatc tgtaaagttg gaggaacaaa atcattttta gatattgtga
     1681 gtatgggaaa tttgtattct ccatttgatg atggctgtat tgagtctatt ataggtgatg
     1741 ttaaatcttg gtttgatgaa ataaatgaca gcaaattata aaaaattatg agaattttat
     1801 tgtataaaag tgaaaaatta aaaaatatat aaaaagtgat tatttgttgt gaaaatagtc
     1861 ttgtttttaa ctaaattgat aaaataaact aaaaaagatt tgtacttaaa aaaaaaagaa
     1921 aatacaagaa atatgcaata tcaacatttg gaaaaaaaag taaaaatgta tacaaaatac
     1981 atataaaaaa actattgcaa attttataga atgtttatat acttaagtca acagagatag
     2041 aaaaaagcta tttatagaaa acaaaggata aattgcttaa ttttaaattt tctgaaaaaa
     2101 ataataatcc ggatgaagag tatgggagac tgctttataa aaagcgaccg aagggacaag
     2161 tttaatctta cttacccaaa agattagatg aaattctcag gtaaaggtga ctgtacttgg
     2221 acggggctct gaaaatgatt ttaacaggga agacaaattg ggagatttgt ttttcctgtt
     2281 ttttatttat caagtaataa ataaaagttt gaaagagagt aaaaaaatga taataattac
     2341 gaataatcca aaagtaaaag aagaagttca aggcagagaa gttttgttta aagacacaac
     2401 ttatattgga atcttagaag caagtagaga tttgatacat gaaggttatg aacttttatc
     2461 tcatccactc tatgggagtg taaaaccaaa tgaaacacct tacaggactg ttatactaaa
     2521 gaaaggaaat cgtttggata taaactcttt aaccttaatt gaagaagcaa tcatcactgc
     2581 aagtaaattt caggataata aaaagactcc aaaatggaca gaaaatgtcc aagacgattt
     2641 tagagtaatt gattatgata tattttataa tacaatacaa agaatgcagt atgaataaaa
     2701 aaatttgtta aaaagttatt gaaacagcct aaatattaaa tctaatttaa tattaaataa
     2761 aatgagaaat ttaattgggg aggataagtc aaaatggaaa atgtgtatga cttagtaata
     2821 attggttcag gaccagctgg gcttgcagca ggtctttatg gagcaagagc aaagttaaaa
     2881 actctaatcc tagaaaaaga caagactggt ggacaaattg taataacaca tgaaattgca
     2941 aattatccag ggtcagttcc aaatgcaaca ggaccaagtt taatagctag aatggttgaa
     3001 cagtgtaaag agtttggagc agaaatgcta agagataaca ttgttgatac tgagctagat
     3061 ggagatataa aagttttaaa aggggaaaag gcagaatata gagcaaaagc agtaataata
     3121 ggaacaggag caacaccaag aaagattggt tgtcctggag aaaaagaact tactggtaaa
     3181 ggggtttcat attgtgcaac ttgtgatgca gatttctttg aagattttga agtatttgtt
     3241 gtaggtggag gagacagtgc attagaagaa gcaatgtatt taactaaatt tgctagaaaa
     3301 gtaacaattg tacatagaag acaaggattt agatgtgcta agagtgttga agaaaaagca
     3361 aaagctaatc caaagataga gtttttatta gatacagtaa ttgaagaaat caaaggtgat
     3421 ggaatattag aatcagttgt atttaaaaat aaagttactg gagaaactca tgaatacttt
     3481 gcagatgaag aagatggaac aatgggagta tttgtgttcg ttggattaga tgctcaaact
     3541 gatttattca aaggtaaagt tgatatggat gaaaaaggtt acataataac tgatgaagat
     3601 atgagaacta acataccagg cgtatttgca gcaggagatt gtagatctaa gactctaaga
     3661 caggttgtaa ctgcaactaa tgatggcgca attgcatcta tagtagctga gaaatacatt
     3721 gatgaaaaat ttgggaacta gaatctgtaa attaagaaat agtgtctgta aatttaatga
     3781 ataatattta aaattaaaat aaaaatttca agggggaata agaaaatgtt agatttagat
     3841 aaggctacat ttgaagaaga agttttaaat gcagaaggtt ttgtatttgt tgatttttgg
     3901 agtgaaggtt gtgagccttg taaagcttta atgccagatg ttcataaatt agctgagact
     3961 tatggggata aaataaaatt ctgtaagatg gatacaacaa aagctagaag attagctata
     4021 aaacaaaaag tattaggtct tccaactatg gctatataca aagatggaga aaaagtagac
     4081 gaagttacta aggatgatgc tacagttcct aatatagaaa acatgattaa aaaatatctt
     4141 taatatgttg ataaagtatt aacattaaaa gaaaaaatct atttttatct gaagataaga
     4201 agaaaaaggt ttttatgtcc aactttgtta aaaaaataat tttaaataaa ataatttttt
     4261 tacaataaat attttttagt aataaaataa agatttaagg cataaaaaca caataatata
     4321 tctttaaaaa aataagataa attgtaaaat gatataattt tgagaaaaac tcaaatgcat
     4381 atacacaaat taaataacag gaggtgcaag tatgcgtctt gaattaggga aaatctttat
     4441 aaaagatatt caatttggtg atgtaacaga agtaaaagat ggagtattat tcatcaataa
     4501 gcaagagatg ctacaagaaa ttggtggaga tgagcatatt aaatctatag atatagaatt
     4561 agctcgtcca ggtgaaagcg taagaataac acctgtaaaa gatgttattg agccaagagt
     4621 aaaagttgaa ggtaatgggg gaatcttccc tggtatcatg tctaaagttg atactgtagg
     4681 agaaggaaaa actcatgctt taaaaggtgt agctgttgta actactggaa aaatagtagg
     4741 tttccaagaa ggtataatag acatgactgg agaaggagct aagtatactc cattttctaa
     4801 attaaataat gtagtagtaa tagctgaacc tattgatggt ttaaaacaat acgctcatga
     4861 aaaagctgtt agaatgatag gattcaaagc agcaatgtac ttaggagaag tagcaagaaa
     4921 tcttactcca gatgaagttt cagtatatga aactaaacct cttcttgaat caataaaaga
     4981 atatccagag cttccaaaag taggatatgt ttacatgctt cagactcaag gtttattaca
     5041 tgatacttat gtatatggag tagatgcaaa acaaatagta ccaactttat tatatccaac
     5101 agaattaatg gacggagcaa ttgtaagtgg taactgtgtt tctgcatgtg acaaaaaccc
     5161 aagttatgtt catataaaca atggggttgt tgaagactta tatgcacgac atggtaaaga
     5221 tataaacttt gtaggtgtaa ttataactaa tgaaaatgtt tacctagcag ataaagaaag
     5281 atcttcaaac tggacttcta aattatgtaa atatttagga ttagatgcag ttatagtttc
     5341 acaagaaggt tttggaaatc ctgatactga ccttataatg aactgtaaga agatagaaat
     5401 gcaaggtgtt aaaacagtta tagttacaga tgaatatgct ggacgtgatg gaggttctca
     5461 atcacttgca gatgcagatg taagagctga tgctgttgta acaggtggaa atgccaacca
     5521 agttgtagtt cttcctaagt tagataaagt tattggacat ttagaagtag tagatgtaat
     5581 agctggtggt tctgatggaa gtttaagagc tgatggaact attgaagttg aaatccaagc
     5641 tataacaggt gcaactaatg aaacaggatt tggtcattta actgctaaag gatattaaga
     5701 agtattttat taaacgattg agtaatgtta ataaaacata ttatagataa ttataataag
     5761 tgttatagat atataaaaat atattagaaa tataataagg aggattatta tgagtttact
     5821 tagtaataaa aaggttctta taataggtga ccgtgatggt ataccaggac ctgcgataga
     5881 agaatgtgta aaaacagtag aaggagcaga ggttgttttc tcatctacag aatgctttgt
     5941 ctgaacagct gctggggcta tggacttaga aaatcaaaac agagttaaag atgctgctga
     6001 taaattcgga gctgaaaatg ttgtgatttt actaggtgct gctgaagccg aagctgcagg
     6061 tcttgcagcc gaaacagtaa ctgctggaga tccaactttc gctggaccac ttgctggagt
     6121 tgccttagga ttaagtgttt accacgttgt tgaggaacca ataaaatcat tatttgatga
     6181 aagtgtatat gaagaccaaa taagtatgat ggaaatggtt ttagaagttg aagaaataga
     6241 agaagaaatg tctggtataa gagaagaatt ttgtaaattt taatgcctaa aagcaaaagg
     6301 ggtgaaacta agagatggga aaactaaaag cagtacatta tattaatcag ttctttgctg
     6361 gtataggtgg agaagaaaaa gctgatacta agccacatgt ggcagaaact ttacctccaa
     6421 taagtttaca acttgataaa ttattaggtg aagatattga aatagttgga acagtagttt
     6481 gtggagatag ctatttcaat gaaaatattg atagtgcaag tgaagaagtt ttatcaatgg
     6541 taaaaggttt tgaaccacaa cttttcatag ctggtcctgc atttaatgct ggtagatatg
     6601 gggttgctgc tggaacaata actaaagttg taaaagatgc tttgaatata ccagctttaa
     6661 caggtatgta tgttgaaaat ccaggagcag atatgttcaa aaaggatgtt tatgtagtag
     6721 aaacttctga ttctgcagca ggtatgagaa aggcacttcc taagatagct aaacttgcag
     6781 taaaacttgc taatggagaa gaaattggaa ctcctaaaga tgaaggatac atagctagag
     6841 gaataagagt taactacttc catgaagaca gaggttctaa gagagctgtt gacatgttag
     6901 ttaagaaaat aaaaggtgaa ccatttgaaa ctgaataccc aatgccaaac tttgatagag
     6961 ttgacccaag taaagctgta aaagatttat caaaatgtaa aatagcttta gttacttctg
     7021 gtggtatagt tccaaaagga aatccagata gaatagagtc ttcttcagct tctaaatatg
     7081 gaacttattc tatagcagga gttatggatt taacagaaga gacttatgaa actgcacatg
     7141 gtggatatga cccagtgtat gcaaatttag atgcagatag agtattacct gttgatgttc
     7201 ttagagattt agaaaaagaa ggtgtaattg gaaaattaca tgagactttc tatacaactg
     7261 taggtaatgg tacatctgtt gcaaactcta aaaaatatgc ttctgaaatt ggagcagcat
     7321 tagtggctga tggtgtagat gcagtaatat taacttctac atgaggtact tgtactcgtt
     7381 gcggtgcaac gatggtaaaa gaaatagaaa aaactggact tccagtagtt catatgtgta
     7441 cagtagtacc tatttcatta acagtagggg ctaatagaat agttccaact atagcaatac
     7501 ctcatccact tggaaatcca gcgcttgacc ctacagaaga aaaagcccta agaagaggcc
     7561 ttgtagaaaa agcattaaat gctttaacta cagaagtaga tggtcaaaca gtatttgaaa
     7621 aataaaaata acacacacat atattatata gataaaaata taaacacaca ctaaaaataa
     7681 aaaataacta tacacaaaaa aaataatata gatttcatga atggataaat tggagttatt
     7741 cattcatgaa atcttaaaaa atgccaaaat acataaacaa taatagaatc aaatatacaa
     7801 taaaatacaa tgattagagc ttttaataag tttaataaga ttaaaaaata agtgttcata
     7861 aaatttatgg aggtgcacaa aatgacttat ccagttttaa aaggggcagg ctatgtactt
     7921 attcatactc cagatatgat agtgcaaaat ggaagtactt gtacagttga aagagcaaca
     7981 aattcagatt cagaattttt aaaagaagta agtaatcata taagaagtta tgaagatgta
     8041 gttaactaca tgccaaatca agtttatata ggaaatagaa gaccagaaga attaagagat
     8101 ttaccaatgc catggtgtga acaaaagatt gagggaacta gaaatggtaa gtttggagaa
     8161 ataatgcctc aagatgagtt catagcttta atgcaaataa gtgatgcatt tgatttagta
     8221 aaattatcac aagaatttat tgatgaagta aagccaaaaa tcgaaaataa ctaccctgaa
     8281 attgcaccat ttgtaggtaa attaaagggt gatgatatag aagaaggtaa agaattagta
     8341 gcaacacaca tagctgaagg attataccat gatggaaaat ttgttggtta tgtaaaaaga
     8401 gcacatgatg tagatgttaa cttaaatgcc catacaatgt ttgaaaatct agtagtaaaa
     8461 gcatctggag ttttatctgc tattcaaatg ctaagacata gcaaaataga ccctgctgaa
     8521 atagattatg ttattgagtg ttcagaagaa gcttgtggag atataaacca aagaggtgga
     8581 ggaaactttg ctaaatcaat agctgagata gcaggacttc agaatgcaac tggttctgac
     8641 acaagaggat tttgtgcagc accaactcat gcattaattc aagcagcagc tttagtaaaa
     8701 gctggcatac ataaaaatgt aatggtagta gcaggtggag caagtgctaa acttggaatg
     8761 aatgctaaag accatgttaa aaaaggtctt cctgtacttg aagatgttgt tggaggattt
     8821 gcagtacttg tatctgaaaa tgatggtgta aatccagtta taagaactga tttaacaggt
     8881 aagcatactg ttggaactgg ttcttcacca caagcagtta tgacagcact tataacttca
     8941 ggtcttgata gagctaattt aaaaataaca gatgttgatg tgtattcagt tgaaatgcaa
     9001 aacccagata taactaagcc agcaggagca ggagatgttc cagaagcaaa ctacaaaatg
     9061 ataggggcac ttgctgttaa acgtggagac ttagaaaaga aagaattgaa agattttgtt
     9121 tctaacaaag gattaccagg atgggcacca actcaaggac atataccatc aggagctcct
     9181 tatataggat ttttaataga tgatttaact acaggaaata gaaatagagc tatgatagtt
     9241 ggaaaaggta gtttattctt aggaagaatg actaacttat ttgatggagt atcttttata
     9301 gctgaaagaa atacaggtgt tactgaagag acttcaggaa tatctaagga tgaaattaag
     9361 aagataatag ctgaatctat gaaaaaacta gcattagata tgttagaaga ataggggtga
     9421 ggatatgtca aaaaaagtaa tcgcagatgt attcttagaa gtagctaatg caatagaaag
     9481 cggcgaattt ggcaaaaaag taaaaattgg tgttactaca cttggaagtg aacatggtgt
     9541 agaaaacatg gttaatggtg cacaattagc aaaatctaat ttatttgata ttgtgcttat
     9601 tggaccaaaa gtggaaactg accttgaagt agttgaagtt aatgatgaaa aagaaatgca
     9661 tgcaaaaatg gaagaattat tagattcagg atatattgat gcttgtgtta ctatgcatta
     9721 taattttcca ataggtgtat ctacagtagg tagagtaata actccagcaa aaggaaaaga
     9781 aatgatactt gcaacaacaa caggaacaag tgctactaat agaatagagg caatggtaag
     9841 aaatgccatt tatggtattg ctacagctaa atcaatgggt aacaaatgcc caaaagttgg
     9901 aatacttaat gttgatggag caagacaagt tgagaagtgc ttaaaagaat taaaagataa
     9961 tggatatgac atggagtttg cggattcaat tagagcagat ggtggatgtg taatgagagg
    10021 taatgattta cttgtaggtg cacctgatgt tatggttact gatacattat ctggaaatat
    10081 atttatgaaa gtattttctt catatactac aggtggagat tatgaagctc aaggctttgg
    10141 atacggacct ggagttggag aagactatga tagaaaggta cttatagtat caagagcatc
    10201 aggttctccg gtagtagcaa atgctttaaa atacgcttat gatgttgtaa agggagatat
    10261 aagtaatgtt gcaagaaatg aatttgcaaa ggttaaaaaa gcaaaatttg atgacattat
    10321 atcctctctt actaaaaaag aagttaaagc tgaaaaagta gaagttaaaa tgccagataa
    10381 agaaattgtt actcgtcaaa tagctggtgt tgatataatg gatttagaag atgcagtatc
    10441 tgagttatgg aaaaacggaa tctatgctga aagtggtatg ggttgtacag gtccaatagt
    10501 tttagtaaat gaagctaaag gagacttagc agttgaaact ttagttaaag ctggatatac
    10561 tgcaaaataa gtacattttt tatatgtaaa taagaacata tagttataat tttattgatt
    10621 ataattatat gttcttttta ttttatatct tgtcaatatt tatatattaa cacaatccat
    10681 ttatttgatt ctctagctaa tttattatat ttattcaatt aaaattaagc tttctaacta
    10741 aataaaaact aatgaagtat taaaatgaaa ttaataaaat atgaaaaaat tttaggaata
    10801 aagtatctgt tagataaaaa taagattaat tagtgatata atataattaa gataaaattt
    10861 attatttgga ggtaaaatca tgagcagagt aaaaaatgta gtaggattgt tgggaactaa
    10921 aggtgttgat gcactatatc taacaaagaa aactaatgta aactatataa gtggttttcc
    10981 tgatgaagaa gcatatgcag tgatttgcaa agatggaaac tttttagtta ctgatagtag
    11041 atatatggag cttgcagaaa aggtttgcaa agattttgaa attataaatt ggcataattt
    11101 tgatagaagt gtggcaaagg cagttaaaag tgtatgtgat aaagtgggta taaagaaact
    11161 tgggtttgaa agaactaata tagtgtttga taaatatgaa gaacttaaaa atctgattga
    11221 gaaggataat ggagaattaa tacctacaga aaatattgta gagactttga gatatgtaaa
    11281 agacaaagat gaaatcaaaa atacaagaaa agcttgtgaa atagcggata aggcattaga
    11341 agaattgatt ccacatataa aagctggagt tagcgaaatt gaactggcta caaagttaga
    11401 gtactttatg aaaatgaacg gagcacaaaa tatagggttt gaaactatac tgatatcagg
    11461 agcaaagact tcattgcttc atggtaagcc tagtgataag attatagaaa aaggtgattt
    11521 tgtacttata gactatggtg ctatgtataa tggctatata tctgatacaa ctagaacttt
    11581 tatagttgga ggagcttctg aaaagcaatt agaaatatat aatttagtta aggaagctca
    11641 aaatgtaggg gttgagaaca tgaaagctgg tgtacatgcg acaattccag atgctgagat
    11701 aagaaaagtt gtcaaaaaat atgaagacta ttactatcaa ggtataggac atggagtcgg
    11761 tagggatgtt catgaagaac ctttcattgg taattatggt gataaaatca tagaagaggg
    11821 atgtataata acaatggaac caggtattta tttccctgga tggggtggag ttagaataga
    11881 agatactgtt ttgattacta aaaatggtcc agaaagactt actaaattcc ctaaagattt
    11941 gatgatttta gacaaataat ttaatttata tatatttttt tacataaaat ataacataat
    12001 ctcactatta agctctattt acatattata gtaaagaggg cttaatttta ttgtaagagg
    12061 tgatagtata tatgtataaa aaacataaat ttataaaaaa tataaaaaaa gcctggtata
    12121 aaatcaaatt aattgataga tgccttataa ttgtaatggc aatattaatg tttcaatcta
    12181 tatataattt atttgttaat gaagtaaatt cacaagatac tacaactatt gatgtagtag
    12241 taagaaccac ttcagcagct atatttgggt attttttaag tgctaatttt ataaagagac
    12301 ctttaaggaa gtatacaaat actgatgtat cttcaaatct ttttatagat aataatttac
    12361 ccccaaaagg tcaagagtct agtcaaaata atataatgaa tgtcaaaaat accattggat
    12421 ttacttcaga agctgataat tatgaaaaga aaatacctat taataataat gaaggttttg
    12481 aagaaggaga aactagtgaa ttgcaaatta ttatagctac tgtaatttgt atagcagcat
    12541 taacagtact ttttgttgta agaaatttta caactacaac atcagcttct ttaggtacta
    12601 tttcacagat gagagatttt gtctcaggat gcgtgggttt tttgctaggt tgtccaagta
    12661 aacctgatta aaaaagtatt atcaataaaa ggtattttaa aaagtatcag tataataata
    12721 tttagattta aatgtataca attataattc tataacattc tatattgtat ttttatactg
    12781 atactctaaa ctatactatt tattaaaata ttttaacatt gtatttaaac aaaatattat
    12841 atctgtataa tataaattta gtttatatga atagatgcca tatactcaat aaaaagtttc
    12901 atactatgag atatgtattg atttcttctc caaagaactc caatatttgc agtaattgca
    12961 cgttctaatg gtattgaaca gagattttct gtattttgaa atatttcttt atacaatatt
    13021 gttgaagcca agtcattttc tagtaaataa cgtatggtag aaagttgatt tgagtgtaaa
    13081 attatatttg gcttagcttt ttcaagtctt tttgtaataa tcttatagtg ataagaacct
    13141 tcagataaga ttacaaaagg tacatttttt aacatataat ttgatataat gggatgtttt
    13201 gccaattcat ttttgggatt tgtaactaag tacaattctg ttttatagat tgtctttgaa
    13261 tctatatcat cataaatatc actgtcaatt ataccaatac aaaaatcaag tgtagattct
    13321 tcaatcattt tagctccaac aaatgttgga acttcaaaaa ttttaagctc tatatctgga
    13381 taaattacat taaatctagg aagtattttt gaaagcaaaa acgtacctaa aactgtagga
    13441 atacctattt tgagagaagc ttttctcttt tttcctaaat caagtgcgtc acattgaaaa
    13501 tcctcaaatt gttttataaa atgttttgac ttgtctaaaa aaatttttcc ttcaggcgtt
    13561 aattctattt tattacctat tctgtaaaaa agttcaaagc caagttcttt ttctaattct
    13621 ttaattgcta atgttatgga tggttgagaa atatgaatac tttccgcagc cttagtcatg
    13681 tttttatatt tacagacagt ttgaaaatag tataaatagt ttatattcat ttggtattag
    13741 ttcctttcat ttacatatta gtgacaagta tataattaac aatagcataa gttttgtata
    13801 ttgttgtaaa aaaatagaat agttttaaac tatcatagca taagtttttg atattttcaa
    13861 tctattaaga atagtgctat tattaaatta acaaaagaga atagctggta tggtttagag
    13921 taaatcaatc tatattacag ttatatcaac gaatatcaaa aaattatcta ttagaaaata
    13981 aaaattattt ttacaattaa attgttaatt aaatcataaa gaaaaaagtg atattaacaa
    14041 gataaaattt ttttaatcag aaatgttaat ttaataacaa aatagagtat tggggagaaa
    14101 ggagaaatat attttttaat aatatttgtt aatttaataa cgaaaaatga aagggagtga
    14161 tttagtgaag tttgaattga tggatttttt aatgaatcct tttgtcctta tgtttgctgc
    14221 agtaattaca ggaattttat ttggaaaaat taaatttggg aagtttaatt ttggggtatc
    14281 aggagcatta tttacaggat tatttattgg atggcttgca tatagcttgg ggaatctaat
    14341 aatagcaaaa ggagaaacag cagcaggata taaggcagca actgtaatga tggggaatgg
    14401 aattatttct tctgacttct ttgatttctt tttaataata tttgttgcag cagttggtct
    14461 attggcagca aaagatatga aagctgtatt aaagaagtat ggagcaagat ttgtaatttt
    14521 aggagttctt ataactttta taggtggctc tatgacttat gcaatgactt tactatcaag
    14581 tgataaagga agtagtgctt atgaagtttc tggcgtttac acaggagcat taacaagttc
    14641 gcctggatta gctgctgctt tagaaacagc tggtaaacat gcagaagatg tatcaaaaga
    14701 atttgaaaaa gcttcaataa aagataaaaa agaaatttta aaagtagtcg acccagaagg
    14761 caaattggat gtgaatacaa ctacatcact gactcaagag caaatagata agtatattgc
    14821 atatgctgaa gctggtgttg gtataggtca tgcagtcgca tatccttttg gagttttaat
    14881 agtaatctta ggtgtaaatt tccttccaaa attatttagg atggacctaa aagaagaaag
    14941 aagaaaatat gagaaggaaa tgaaggaagc aagagatagt gtttctggta aaacgatacc
    15001 agaagttcca tttaatataa taacattttt cttgacatgt ttagctggat acttagttgg
    15061 aggaatacat gtatttatgg gaccactagg gtacttcaca ctaggcgcaa caggaggttc
    15121 actaattgta tctctagttc ttggatatat aggtaagata ggggtagtaa atttcagaat
    15181 ggaagaaaag gttttaaata ttttaaaaca aatagggcta gtatttttct tagcaatagt
    15241 tggattaaga tatggtggaa aagtagttga ttcaattatg acatctggta tgcacctagc
    15301 cttagtagca atagcagtag gtgttacagc tatgatgata ggattcttag ttggcaaata
    15361 cgtatttaaa ttaaattgga ttttattatc tggagctgtc tgtggtggta tgacatcaac
    15421 accaggtctt ggagctgctg ttgatgctct tgatagtgat gacccagcag caggttatgg
    15481 tgctacgtat ccatttgcat tattaactaa agttatattg gttatagttt tacacaaact
    15541 tccaatgtaa ataagatttt atatgggggg atatttatga ataatgaagg agcatttgaa
    15601 gaattaagtg gaagattaag aaataaagaa ttgtgtgatt taataatgaa tgcagatgaa
    15661 gctgctaaaa ttatagagga tggcatggtt attggagtta gtggatttac accttcaggc
    15721 tatccaaaag cagtaccatt agcagtttca gaaagagcta aaagtggaga aaagataaaa
    15781 ttaaccgtat attcaggagc atctttaggc ccagaagttg atggagcatg gtcagaagca
    15841 ggtataattg aaagaagact tccttatcaa actaattcaa tacttagaaa taatattaat
    15901 aaaggtgttg ttgattatat agatatgcac ctaagtcatt ctactcaatt tttaaattat
    15961 ggaactatac ctaaagtaga tgtagctata gtagaagcac ttgcaataac tgaagaaggg
    16021 aatattatac caactagtgg gataggtaat tctccatctt ttataaaaag tgcagataaa
    16081 gtaatagtag agataaatct tgcaaaacca atggaaatgg aaggtatggc agatatatat
    16141 attacggaaa atccaccaaa tagaaaacca atagaaataa atcatcctaa ggatagaatt
    16201 ggaacaacat atataccttg tggtttggat aaaattgcag gagtagtaat taccaatatg
    16261 caagataaga cccgtccatt gggggttgta gatgaagctt cgaaaaaaat atcaaataat
    16321 attattgctt ttttaagaga agaagtaaag gcaggcagat tatcaaagaa tttacttcct
    16381 cttcaatctg gtgtaggaag tgtagcaaat gcagtattat atggattatg tgaatctgaa
    16441 tttgaaaatt taacttgtta tacagaggtt gtacaggact ctatgttgga tttaataaga
    16501 atgggtaaag ttacaatggc atctactaca tctgtaagtc catctccaga aggattaata
    16561 aaatttgaaa aagatattga tttttttaag gataagatta tattaagacc tcaagaaatt
    16621 agtaacaatc cagaaatagc cagaagaatt ggtgtaattg caatgaacac tgcaattgaa
    16681 gttgatattt atggaaatgt aaattctact cacataatgg ggtcaaagat gatgaatgga
    16741 attggaggtt ctggtgattt tgctagaaat ggagcaataa ctatatttag tactgagtcg
    16801 attgcaaaaa atggtgatat atcatcaata gtacctatgg tatctcacgt agaccacact
    16861 gaacatgatg taatggtaat tgtaacagaa caaggatatg ctgatttaag aggtcttgca
    16921 cctagagaaa gagctataaa aataatagaa aattgtgccc atccagatta taaagaacaa
    16981 cttagggatt atttaaatag agcttgtaaa agtggagcaa aacaaacacc tcacatattg
    17041 gacgaagctt tatcatggca tagtaaattt atgagtacag gtacaatgaa aaaggctgaa
    17101 acttttaaaa gtgcattata aaatatttaa taaattggag gtagatttta aatggaaaaa
    17161 gcagtggaaa actttgaaga tttaagtaag gaatacatta atggttatat tgagagagca
    17221 agaaaagctc aaagagagtt tgaatgttat actcaagaac aagtagataa aatagtaaaa
    17281 atagttggaa aagtagtgta ttataatgct gaatatttag ctaaacttgc tgtagaagag
    17341 actggaatgg gagtatatga agataaggta gctaaaaata aaagcaaagc aaaagttata
    17401 tataacaatt taaaagataa aaaatcagtt ggtataattg atatagatag agaaactgga
    17461 ataacaaagg tagctaaacc agttggagta gtagcggcaa taactccttg tacaaatcca
    17521 atcgttacac ctatgagcaa tgcaatgttt gcacttaagg gaagaaatgc aattattatc
    17581 acacctcatc ataaagcaat tggatgtagt acaaaaactg tagagatgat taatgaagaa
    17641 ttagaaaaaa taggagctcc agaaaattta atacaaatac ttgaccaaca atcaagagaa
    17701 aatacaagaa atttaatttc atcagcagat gtagtaattg ccactggagg aatgggaatg
    17761 gtaaaagctg cgtactcaag tggaaaacca gcacttggtg taggggcagg aaatgttcaa
    17821 tgtatcatag atagagatgt agacattaaa gaagcagtac ctaaaatcat agcaggaaga
    17881 atttttgata atggtatcat ttgttcaggt gaacagtcag taatagtagc agaagaaatg
    17941 tttgataaaa taatggatga atttaaaaat aacaaaggtt ttatagttag agataaagta
    18001 caaaaagaag ctttcagaaa tgctatgttt gtaaataaat ctatgaataa agatgcagta
    18061 ggtcaatcag ttcatacaat tgcaaaaatt gcaggtgttg agataccaga agatacaaaa
    18121 ataatagtaa tagaagctga tggaccagga gaagaggata ttattgcaaa agaaaaaatg
    18181 tgtccagtta tatctgcata caagtataaa agttttgaag aaggtgtagc tattgcaaaa
    18241 gcaaatttaa atgtagaagg aaaaggacat agtgtatcta tacattcaaa tacagttaaa
    18301 aatatagaat atgcaggaga aaatatagaa gtatcaagat ttgttattaa tcaatgttgt
    18361 gctactagtg ctggaggaag tttctttaat ggtcttgcac ctactaatac tctaggttgt
    18421 ggttcttggg gaaataacag catctctgaa aatcttgatt ataagcatct aattaatatt
    18481 tctagaattg cttattatat gccagaaaat gaagtcccta cagatgaaga actttgggga
    18541 taaaacttag acaaaaaata ttcattctaa attaaagtag gaatatattt taatttagaa
    18601 tgaatttaag acataaatta aatttaaatt agtttattgg actaaattta aaatattaag
    18661 agacatatag aagaaggaag tattataatt taaaataaat aaaaaaatct ataaaagaga
    18721 aggagtggtt ttattatggc attaatgaca ggagctcaat atattgaaag tttgagaaaa
    18781 ttaaatacta aggtttatat gtttggtgaa gaggttaaga attgggttga ccatcctatg
    18841 attagaccat ctataaattg tgtagcagca acttatgact tagctcatga cccagaatat
    18901 gcagatttaa tgacagttac ttcaaatatc acaggtgaaa aaataaatag atttggtcat
    18961 cttcatcaaa gtgttgatga tttgataaaa aaagtaaaaa tgcaaagact atgtggtcaa
    19021 aaaacagctt cttgtttcca aagatgtgtt ggtatggatg cgtttaatgc agtgtattca
    19081 acaacatttg agtgtgataa agcccatgga actaattatc atgataattt tgtaaaatac
    19141 ttaacttata tacaagaaaa cgatttagta gttgatggag ctatgactga ccctaaggga
    19201 gatagaagtc tatcacctag tgctcaacct gacccagata tgttccttca tatagtagaa
    19261 agaagagaag atgggataat tgtaagagga gcaaaggcac atcaaactgg ttcaataaat
    19321 tcacatgagc accttataat gcctactata agtatgactg aagcagataa agactacgct
    19381 gtatcatttg cagttccttc agatgctgaa ggtgtgttta tgatttatgg aagacaatct
    19441 tgtgacacca gaaaattaga agaaggtgca gatgttgatt taggaaataa ggagtttgga
    19501 ggtcaagaag ctttagtagt atttgataat gtatttgttc caaatgatag aattttctta
    19561 tgtggagaat gggatttctc tggtatgtta gtagagagat ttgcaggata ccatagacaa
    19621 agttatggtg gatgtaaagt aggagtaggt gatgtaataa taggagcagc agctttagca
    19681 gctgattata atggagcaaa caaagcttca catataaaag ataaactaat agaaatgact
    19741 caccttaatg aaagcttata ttgctgtggt atagcatgtt catcagaagg tcacaaaaca
    19801 gaagctggaa actatcaaat agatttactt cttgcaaatg tgtgtaaaca aaatgtaact
    19861 agatttcctt atgaaatagt aagacttgca gaagatatag ctggagggct tatggttact
    19921 atgccttcag aaaaagactt taaatcagac cttaaagttg gaacaagtgg aatgactatt
    19981 ggcgaagtat gtaacaagta ttttaaagct tcttcagtgg cttcaacaga agaaagaatg
    20041 agaatattaa gattcttaga aaatatatgt cttggttcat ctgctgttgg ttatagaact
    20101 gagtcaatgc atggggcagg ttcaccacaa gctcaaagaa taatgatttc aagacaagga
    20161 aacataaatc aaaagaaaga attagctaag aaaattgcgg gaataaaaaa agaggaagct
    20221 ttaaatttat aaaaagttga tatataaagg gaaattatat attaatgtgt attaattaat
    20281 gaaaagatat gtagtataag agatagttat aaaattatgg tggtttttag ctaagtaaag
    20341 aaatttttaa taaggagaat ttacacatga cctgtggagt tagattttgt gggggctgta
    20401 accctagata cgaaagaggg aaggctctta caataatcaa agagcacttc aatggtaggg
    20461 tagattttag catagcacaa gagaacgtcg agtatgattt gctacttata attggaggat
    20521 gcgcaactct atgcgcatcc tatcaacaat ataaagtgaa aaatgaatgt gttaagatgt
    20581 gggattttag ccatatagaa agagttataa atgtgattga atcagcaatt tgtgaaactt
    20641 aaaaaagcta aatgggggga tttcattgag ttggcaagaa ttgtatcaaa gtaaattatg
    20701 tagtgctaca gaagctgtaa aacagattaa aaacggtgat actgtagtat ttgcacattg
    20761 tgtaggtgaa cctcctgcac tagtagaggc tatgattgaa aatgctgaac aatataaaga
    20821 tgttgagatt aaacatatgg taagcttggg tagtggtgga tatactgcta agggaatgga
    20881 agctcatttt agagtaaatc caatgtttgt aagtggaaat gtaagaaagg caattgaaaa
    20941 tggagatggt gattttacac ctgcattctt ccatgaagta ccaaagttgc ttagagaaaa
    21001 aagattaaaa tgtgatgttg ttttagcaca ggtaactcca ccagatgaac atgggtattg
    21061 tagcttagga acatcagttg attatactta tgaagccatt aaaactgcta gaacagtaat
    21121 tgttcaagtg aatgaccagt ttcctagaac ctatggtgag gtagtccatg tatcagagtt
    21181 tgactatata gtggaaaaat cacaaccttt atttgaacta caacctgcaa agattggaga
    21241 agtagaagaa gcaattggta aaaattgtgc ttcattaatt gaagatggtt ctactttaca
    21301 gctaggtatt ggtgggatac cagatgcagt tatgttattt ttaactgata aaaaggattt
    21361 agggattcat tcagaaatga tttcagatgg gactttggcc ctttatgaaa aaggtgttat
    21421 aaatggtaaa tataaaaatt ttgataaaga aaaaatgaca gttaccttct taatgggtac
    21481 taaaaaatta tatgactttg caaataataa ccctgcagta gaggtaaaac cagtagacta
    21541 tgtgaatcat ccagcaatta taatgaaaca acataagatg gtttctataa attctgctat
    21601 acaagttgat ttaatgggac aggtagttgc agaggctatg ggacttagac aatttagtgg
    21661 tgttggaggt caagttgact ttatacgtgg agtgtctatg ggggaagatg gaaaggcaat
    21721 tatagctatg ccttcaataa ctacaaaaaa agatggtaca gtaatttcaa aaatcgtatc
    21781 tattgtggat gaaggtgcac ctataacgac atcaagaaat gatgttgact atattgtaac
    21841 agaatacggt atagcagaat taaaaggaaa atctcttaga gaaagagcaa gaaatttaat
    21901 aaatatagct catccaagtg taagagaaag tctagcagta gaatttgaaa agagatttaa
    21961 ggagaaatat taataataga ggggtgttaa taatggaagc acttagagta gttccaaaga
    22021 tattttattt tgatacattt aaagaattta atgaagaatt taaaatagga aaaaatgatt
    22081 tagtaattac taatgagttt atatatgagc catatatgaa acctcttgga atagatacaa
    22141 atttaatttt tcaagaaaag tttggaacag gtgaaccatc tgatgaaatg atagactcca
    22201 tgacaaagga aatgaagaaa tacaattttg atagaattat tgcgtttgga ggaggaacaa
    22261 tagttgatat atgtaagata ttagcacttg atgttccaga aaagtctatt gatttatttg
    22321 aaggagaagt atcacctaaa aaagtaaaag agttagtagt agttcctaca acatgtggta
    22381 caggtagtga agtaacaaat gtagctattg cagagttaaa atctaaacat actaaaaagg
    22441 ggcttgcagt agaagaaaca tatgcagact atgcagtgtt aattccagag acagtaaaag
    22501 ggttacctta caaattcttt gttacaagtt cggtagatgc tcttatacat gctattgagt
    22561 cttatctttc tccaaaagca agtccattta cagagatgta ttctctacaa gcaataaaaa
    22621 tgattatgga tgggtataag aagatagttg ataaaggaga agaagagaga tttaatcatc
    22681 ttagagactt tgtacttgca tcaaattatg caggaattgc ttttggaaat gctggttgtg
    22741 cagcagttca tgcactatct tattcaatag gtggagcttt ccatgttgca catggtgaag
    22801 caaattatca gttctttact gaagtattta agatgtattc tagaaaaaaa cctaatggaa
    22861 aaattataaa atgtacaaaa attttagcag atgcccttga atgtgaccct aactgtgatg
    22921 tttatggaga attagaaaag tttttaaata aattaatagc taaaaaagct ttgagagaat
    22981 atggaatggt ggaaagtcag atagatgaat ttacagatag tacaatagca aatcaacaac
    23041 gactacttgc taataattat gtagagctta gtagagagga aataagagag atatttgcaa
    23101 atctttatta atacaatttt ttatttatat gtatagtcaa cataaacaat gctaattata
    23161 tttatgtaca aataaaaata agggaactta aattttaatt aaagttaagt tctcttattt
    23221 ttatatggag ttaaatataa gtatattttt aatttaaaat atgcttatat ttaagtctat
    23281 tactttattt gaaacaattt gtagaatttc aaattccttg acagtaataa gtaagtaatt
    23341 gtataatcaa actgcaatat attaataata ttagtgaaaa tgaaaggatt ataaaatatg
    23401 tataaatcag aaaatttttc aaaaaaatct gtattaataa attcattttt aagtaaattt
    23461 ttaaaaataa ttggatgggg tttggtaagc ttatttacat tatcagcctt agtactttca
    23521 actatttcca ttataattgg atgggctgta atacttccta ttcaagtatg tgcagtattt
    23581 ttacttatag gaggagtttg tatttttaaa ggtaagagat taggagacca aatttctcgt
    23641 tataaaaaat attgtacaat tataaacaat agaaatatta ttccagtaga acttattgca
    23701 gaaaacacat ctaaatcatt aaattttata ataaaagatg tacaaaagat gatagacaaa
    23761 aactacttta taaatactta tattgataaa agaaataatc agattgtgtt aacaaatgaa
    23821 gattttattc caccaagata tgaagatgta gcatatgaag tcaaagaaga agaaaagact
    23881 gatgaatcca atgaagttga tacaattata aataaaggaa tgaattatct aacacaaata
    23941 aaagaagcta ataaaaatat taaatcagaa tcaatgggcg ataaaattgt acaagtagaa
    24001 gatgttacaa gtaaaatatt tgatgttgta aaacatgacc catcaaaact tactcaaata
    24061 caaaaattta tggattatta tcttccaacc actttaaaac tattaaattc atatcataca
    24121 ttggaagaac aaggaattga tagagaaaat ataacaacaa ctatggaaag tattgaaaat
    24181 acaatgaata cgattgtagt agcttttgaa aatcaattgg actatctgtt tgaagatgaa
    24241 gccattgata tttctacaga tattactgtt ttagagaata tgttagtcca agaaggatta
    24301 acgagtggta aattttaact tcaatagaaa aaatattctg ttatttttaa acaattaatt
    24361 agtcataaag tataaaatgt gtattatata agttaatcag tactttatga aggaagagga
    24421 gagaaagata caatgaataa tttagatgat ataccagtta tgccaacttt gacacttgac
    24481 ccatttggag aagaatcaaa cactaatgat atagataatt ctgacttatt aatgaaaaag
    24541 gatgaaaaag acccagaaga agaaaaactg tctgaatctg aacgcaagat ggtaaaggaa
    24601 tttgcggaaa aaatagatat tacaaataca aatatgattt tgcaatatgg agctggtgct
    24661 caaaaaaagg tagcaagttt ttctgaaaca gctttaaaga gtgtaaaaac aagagattta
    24721 ggagaagttg gagatatgct tacaaatcta gttactgatt taaaagcatt ttcagcagat
    24781 gaaaaagaac aaagtggttt tttaggaatt tttaaaaagg caaataataa aatttcaaat
    24841 ttaaaaacta agtatgatag tgcagaggta aatgtggata aagtaagtaa agagcttcaa
    24901 aagcatcagg ttaaaatatt gaaagatata gcaatgcttg ataagatgta tgaattgaac
    24961 ttagcttact caaaagagct tactatgtat attatagcag gaaaacaaaa attaaaggat
    25021 atgaaagaat atgaaatgcc aaagttgaga gaaaaagctc gtttatctgg ttcaacagaa
    25081 gatgctcaat ctgtaaatga tatggtttca ctttgtgaca gatttgaaaa gaaaattcat
    25141 gacttagaat taactagaat ggtatcgctt caaatggctc ctcagataag attggttcaa
    25201 aatagtaata atctgatggc agaaaagatt caatcaacta tagtaaatac cattccatta
    25261 tggaaaaatc aaatagtgct tgctcttgga atttctcact taaatcaagc tatgaaagca
    25321 cagcgtgaag ttagtaatat gacaaatgag cttttattga agaatgcaga aactttgaag
    25381 atgggaacaa tagaaacagc aaaagaatca gaaagaggaa ttgtagatat agacacaatt
    25441 aagaaaacta atcaatctct aatatctact attgatgagg tagttaaaat acaacatgat
    25501 ggtagaataa agagacaaga agcagaagtt gaattatcaa aaatagaaaa tgaacttaaa
    25561 agtaagcttc ttgaatttac agttaaataa aaattatact aatataaaaa gagactgtct
    25621 caaaatagag ataagtctct ttttcattgt ttaaatgatt aaagtatatt tatattataa
    25681 atttctatta tcttttaaca taacatcatg agctccacct tcaactatac tagtagaaga
    25741 tacaagtgta agtttagcat ttttttgaag ttcaggaatg ctaagtgctc cacagttaca
    25801 catagtagaa cgaactttac ttaaagaaag agttacattg tctttcaaag aaccagcata
    25861 aggcacataa gagtcaacac cttcttcaaa agaaagtttc ttatctccac caaggtcata
    25921 tctttgccag tttctagcac gagcagaacc ttctccccaa tactctttca tataactacc
    25981 atttatatta actttgttag ttggactctc atcaaaacga gagaagtatc taccaagcat
    26041 tataaaatct gcacccatag ctaaagctaa agttatatga tggtcataaa cgataccacc
    26101 atcagagcaa attggaatat aaatacctgt tttttcaaag tattcgtctc tagcttgagc
    26161 aacttcaatt atagaagtag cttgtccacg tcctatacct ttttgttcac gagttataca
    26221 tatagaacca ccaccaatac caactttaac gaagtcagca ccagcttcag ctaggtaaag
    26281 gaatccctcg cggtcaacta catttccagc tcctacctta actgtatcac catatttttc
    26341 acgaatgaaa tcaagtgtta ttttttgcca ctcagaaaaa ccttctgaag aatctataca
    26401 taaaacatca gcaccagctt caactaaagc aggaacacgt tcagcaaagt ctctagtatt
    26461 aataccagct ccaactacat atctcttaga agaatctaaa agttcaagtg gattttcttt
    26521 atgagaagag taatctttac ggaataccat atacataaga ttaccattat catcaagtac
    26581 aggaagagaa ttaagtttgt ggtcccatat aatgttgttt gcttccttta aagtaacatc
    26641 tttgttagca taaactatag atgacatagg agtcataaat tcactaactt tagtatctaa
    26701 atccatacga cttatacgat aatcacgact tgcaacaata cccaataatt taccagttga
    26761 agttccatct tcagtaacag ctactgtaga atgtccagtt ttttctttta agtcaagtat
    26821 gtcttttaat gtgttatcag gtttaatatt tgaatcactt acaacaaaac cagctttgtg
    26881 ggatttaaca cgtgctacca tagcagcttc attttcaata gtttgagaac cgtatataaa
    26941 tgaaatacca ccttctttag caagtgcaat agccattttg tcatcagaaa cagattgcat
    27001 aatagcagaa gtcaaaggta tattcatata aatatctgct tcctcgccct ttttaaattt
    27061 agtaacaggt gtttttaaac ttacattagc aggtatacaa tcagtagaag agaaacctgg
    27121 tacaagaagg tattcactga aagtatgtga tggtgtatca aaataaaacg ccatttttta
    27181 atcactcctt atatttttat actttttata attgatagta ttaattataa cttattcttt
    27241 aattttatta aagtattttg tcaaatattg agatttttga aaaatttaaa ctattttaat
    27301 taaatttgtt taatatatat tgccttatag ggtaaagttg tatattaaat aatgtttagt
    27361 gtttaatagt agctaattta aaattaatct ttagtgattc atataattac atttgtatag
    27421 tttatattga taatattact agagagtgca taaacctcaa aaatacagat aaattaaatc
    27481 tatattagta tatccaaaag tacatttaat aaatttattt aactgaatta ttattttcat
    27541 ttctattaaa tttaaatatt ttataaaaat agtattattt acaaaatcat atactccaaa
    27601 atactacata aataaaatta aacaaaaact aaaatgacaa atgtcattat ctaaagtgac
    27661 atagaaacgg tttcttaaag ttgttactat aaaatataaa ctctataata aaagtataac
    27721 aaaagggaat catatcgata tagaatataa ttcaagagga ggtaaaatta tgagtagttc
    27781 taatcaatcg acaataaaga catctataca gcgagtaggg aaatttttaa gtggtatggt
    27841 aatgccaaat ataggagctt ttatagcatg gggtcttata acagcattat ttataccaac
    27901 aggatggatg cctaatgaaa aattgagtac tataggcgac ccaatgataa aatacctttt
    27961 accactattg atagcttata ctggtggtaa agcaatagca ggacaaagag gtggcgtaat
    28021 aggtgcagca gcagctatgg gagtaattgt tggtgcagat ataccaatgt ttatcggagc
    28081 aatgataatg ggaccatttg caggatgggt aattaagaag tttgataaat ttgtagatgg
    28141 aaagatacca acaggatttg aaatgttagt aaataacttt tcaataggta taataggtat
    28201 gcttcttgca atactaggat tttatgcaat tggaccagca atagtagcag ggacagctct
    28261 tatagaatct ggagttcaat ttatagttag caaaagttta ttgcctctag tttcagtatt
    28321 tatagaacct ggaaaagtat tattcttaaa caatgcaata aatcatggta tattagggcc
    28381 tataggtata gctgaggcaa aagaagcagg taaatctata atgttcttac tagaaagtaa
    28441 ccctggacca ggtttaggag ttctattagc atattggatg tttagtagag gaagtgtaaa
    28501 acaatcagca ccaggagctg taataataca tttctttggt ggtatccatg aaatttactt
    28561 cccatatatt ttaatgaatc cagttttaat attggctaca atggcaggtg gagcagcagg
    28621 aatattgact ttttcaatat taggagctgg gcttgtagca gcaccatcac caggaagtat
    28681 atttgcactt atggcactag ctccaaaggg aggattactt ccagtattag caggagttgc
    28741 agtggcaaca gttgtatcat tcttagtggc agcaccattt gttaagagag cttcagcaaa
    28801 tcaaagtgaa gaagacagta cttctttaga agaagctaaa gcaaaaatga gtgatatgaa
    28861 atctgcaagt aagaactctg agaaaaatat tgaggaaaaa cagcttgaag taaatgagat
    28921 taagaagatt gtatttgcat gtgatgcagg aatgggttcg agtgcaatgg gagcttccag
    28981 atttaaaaat agaataaaaa acttagactt aaatatagaa attacaaatt catctgttga
    29041 taatcttcca gatgatacac aaatagtagt aactcacaat acattagttg aaagagttgc
    29101 taagaataat tcaagtgttg agatagtttc aataaacaat tttttaaatg acccaaattt
    29161 agatgcatta tttaaaagat tagaatctaa ataaaaataa aaagtaccac taattaggag
    29221 tggataattt gaaaaaaaag aagattacat ctaggcaaaa aaagataata ctaatgatag
    29281 tagaaaattc aaagaaaaac attccaataa ctatttctga gattgcaggg actttagagc
    29341 taagttcaag aactgtactt agagatatgt ctggaattga aaaatggttt gatgaaaatg
    29401 attttaactt tgtaaaaaaa ccaggagtgg gattgatttt agaggaaaat atagaaaatc
    29461 aaaactttat aattgagttg ttagaagaag aaaaaataga aaaagaatac agcaaggaag
    29521 aaagaaattt aattatatta tcaaagctac tagtttctaa cgagccagta aaatcctatt
    29581 attttgcaaa aatattaaag gtatctgaag gggtactgaa taatgatttt gccttagcaa
    29641 gtaaatggtt ggaaagattt gatattgagc ttgttagaaa accagggctt ggtgtctact
    29701 taaaaggtca agaaaaaaac tttagagagg catatgtaaa tcttatatac gattcattca
    29761 atgaaaaaga aatactagat atggtcagaa atataagtga aaatatacaa acagataaag
    29821 caatagaaat tttaagtgaa aatagacttt taaatttaat ggacaggtgc ataataagaa
    29881 aagttgaagc tacattaaca aagaagcttt cagatttaga tgtaaattta gctgatagtg
    29941 catatatagg gcttgtagtt catatttcat tagccttaca gaggataaaa aatggtgaaa
    30001 atataactat ggataaagag tttctaaaag aattatctat aacagaagag tttaaattag
    30061 ctaaagaaat cgtaaaaggt atggaaacag attttaacat ggatatacca gtagatgagg
    30121 ttggatatat aactatgcat ataagaggtg caaagcaaag gtcatcttca aaccataagg
    30181 ctttaaactt agatgatata gaaataatgg aaattacaaa taagatgata gatttggcgg
    30241 aagatgaatt taaaataagt ttaaaaaatg acgagaggtt atttaaagac ctagcaaatc
    30301 acttagggcc ttctataaat agattgaata tgggattaga aataagaaat cctcttttag
    30361 atgaaataaa aagcaagtat tcatatgcct atgatggagt tgaaaagatt tctagaatta
    30421 taaaagataa actaaatata aattcaatac ctgaatcaga aataggatat attgcaatgc
    30481 actttgcatc agccatagaa aaaaatctta tgatgaatac taatataaat attgttgtgg
    30541 catgtcccac tggaataggt acttcaagat tcttatcaac taagattgaa aataaatttc
    30601 ctaatttaaa tatacttgaa accatatcag ctataaacat agatgaagag tatttaaaag
    30661 aaaaagatgt tgatttaata gtgtctacag ttgagttaaa tacaagttta aattatatat
    30721 gtgtaggtcc atttatgagt ttagatgatg aacagataat caaggaaaaa ataaaatcta
    30781 tagctcaaaa taaattaatc aatttaaatg cgaaaaatga tactaaaagt aagaataaag
    30841 tatatgaaca gataacagaa agtatgaata taggaaaaga tattcttcaa tttttagagg
    30901 aaattagatt tgaaaaattt gaaagtaaag atttaagtga gcttattgaa gactcatcaa
    30961 aaatatttgc aaaatctagt gaagatataa tctctataaa agaatcgtta aaagaaagat
    31021 taaaaatctc aattccatat atagaagaat caaaaattct attgttacat tgtatgagtg
    31081 aaagaataga tattatgaag ttatcaataa taaaactaga gaatagaatc gtgctagatt
    31141 caaatgaaga aatcgataat gtagttttta tgttacttcc taaaaattca ccaagttatc
    31201 aaagacaaat aatgagtgaa ataagtggtt cattaataga caatataatt tttactaata
    31261 agataaataa attctctata gaagagatga cattagaggt aaaagatata gtttttaatt
    31321 tttatacaaa cagattaaaa gcatttatag ataaataaaa ttaatattaa aaaggaaggt
    31381 tgatactatg agtaaagtat tgaatgagaa taatatattt ttagggttag atagtgtttc
    31441 aaaggaagaa gctataactt tagcaggaag aaaattagtt gaaaatggat atgtaaaaga
    31501 agaatatata ccagcaatgt tagaaagaga aaaagtaatg actacatata tgggaatggg
    31561 agttgctatt ccacatggtg taaatgaagc aaaaaaagaa atattatctt ctggaatagt
    31621 tatattacaa ttccctaatg gtatagattt tgatggagaa aaagcatatt tattaatagg
    31681 aatagctggt gttggagatg aacatttaga aatactatct aatatagcag tagttttaga
    31741 tgatgactta acagaaagac taaaaaattc aaatgacaaa caagctttta tggaagcttt
    31801 tgccaactaa tcttaggagg gatttaaaat gaaaaaggcg attcagtttg gagcaggaaa
    31861 tattggaaga ggttttattg gaagcttgtt agttaagtcg ggttatcatg tagtatttgc
    31921 tgatgtaaat gaggagatat taaactcaat aaacaaagat aaaaagtata ctatacacat
    31981 aagagatgta gaatgtatag atgaagtaat tgataatata agtgcggttt catctataaa
    32041 agaagaaata atagatgaga ttgtacaggc tgaaataata actacagcag ttggaccttt
    32101 agttttgact aaaatagcct ctacaattgc aaaaggtata aaagctagaa aagaaaaggg
    32161 attaacaagt aatctaaata taatagcatg tgaaaatgca atatacgcaa gttcttcttt
    32221 aaaagaagag gtacttaagt atttaaataa ggaagaagta gaatatttag agatgtatgt
    32281 tggttttcca aactgttcag ttgatagaat agttcctcct ggtaaaaacg aaaatcctct
    32341 tgatgtaaca gttgaaaatt tttatgagtg gaatgttgaa aaacaaggat ttaaagggga
    32401 aataccaact atagttggaa tgaatttagc tgataacctt atggcttata tagaacgtaa
    32461 attgtttaca ctgaatacag gtcatgctat aacagcttat ataggatatt taaaaggata
    32521 taagactata gaagagagta taaaagataa atttatctgt gatatagtca aaagtgcaat
    32581 ggtagaaagt ggagaaggat tgattaaaaa atacaatttt gactcagaag tgcactataa
    32641 atatattgat aaaattttaa atagatttaa aaatccatat cttaatgatg atgtattaag
    32701 agtcggaagg gaaccattaa gaaaactaag tgataaagat agattgatta aacctttaat
    32761 gacagcaaaa tcatatggat tatcagttga caatttgatt cttggaatag gtgcagcgct
    32821 tcattataat aatagtgaag atactcaaag tgtagaatta caagagttga taaagtctat
    32881 tggggtaaaa aaagccgttg ctaaaatagc taatataagc aatgacgaag aaattttaaa
    32941 taatatcgaa aaaagttata tatttatgaa aaatttataa atttacttga aaaaaagtag
    33001 ttctgataaa gtaactataa tatattattc tacacagttt gaattatttg ttgaataata
    33061 gagaattata atatataatt aaaaggaata aattaatata tttacctgta tatgtttgat
    33121 aatatggttc aaatgtttct actaagctac cattaatagc ttgactacag gagtgaagaa
    33181 gatatagttt atacttattt taaattatat attaagttaa ttactttgaa ttttaagctc
    33241 ctgtctatga tatagacagg agctttttta gtattttaat ataaaatact tacaagaata
    33301 gatagcaaaa ttagaacaaa tataattttt ttattaatat aattttagaa agggctaggt
    33361 ggaagttcaa tgaaggcttt acaagaaaag atattgagag aaggcagtgt ttcaggaaat
    33421 gatatactaa aagttgatag ttttttaaac catcaaattg atgtagcttt tttaaatgaa
    33481 ataggaagag aatttaaaga gagatttaaa ggagaaaagg tggataagat atttacaata
    33541 gaggcttcag gaatagctat agcatcaatt gtttcacagt attttgataa tgcacctgta
    33601 gtatttgcaa aaaaatcaga atctaaaaat ttggataaag atgtatatga aactaatgta
    33661 tattcattta ctaaggcaag agagtattca gttaaagttt ctaaaaagta cataaacaaa
    33721 ggcgaaaata tattgatagt ggatgatttt ttggcaaatg gaagagctgc tcttggactt
    33781 aaagatttaa ttgagcaagc agaagctaac ttagttggag taggaattgt cattgaaaaa
    33841 ggatttcaag ctggaggagc acttttaaag gctaatgatg taagattaga gtctttggca
    33901 gtagttgaat ctatagataa tggaactgta aaatttaggt aatttatgat attatataat
    33961 tgtgtttagc acatatttta actatgtaat tatggaggat tttttatgag gttttttata
    34021 gacacagcca atattgaaga aataaaagaa gcaaatgatt taggtgtaat atgtggtgta
    34081 actactaatc cgtctctaat agctaaagaa ggtagagatt ttatagaggt agttaaagaa
    34141 ataagtgaaa tagtagatgg gccaataagc gcagaagtaa taagtttaga acataaaggt
    34201 atgatagagg aagcagaaaa attatctaag atacataaaa atatagttat aaaaatacct
    34261 atgacagcag aaggtctaaa agcggtgaaa gtactatcaa gtaaaggtat aaagactaat
    34321 gtaacgctta tattttctgc tggacaagct cttttagctg ctagagctgg agctacatat
    34381 gtaagtcctt ttgttggtag attggatgat atatcacaaa atggtcttga tttaattgaa
    34441 gaaatcgttg atatatttag tgtaaatagt attgaggctc aaataatagt tgctagtgtt
    34501 agaaatccaa tacatgtttt acaagctgct agaatgggag cagatatagc aacagttcct
    34561 cttaaagtta taaaccaaat gattaagcat cctttgacag acaaaggaat agatagcttt
    34621 atgaaggatt gggaaggtgc ttttttaaaa ttataattat aaactacgct ttataagtat
    34681 attaaagagg ttattatgga aattctaagt aataaggcta ggctattttg cctagtctta
    34741 ttttggtgta taatatattg aaacatatta ttgaaataga ttaatttttt aagtgaggag
    34801 gcgaaaaatg gataaaatat taagagagat acaaagagaa gataaaaaaa atccatatac
    34861 tgaccaagaa cttgctgaaa tgttaaatgt agctaggtct gaagtgatat cagttaggaa
    34921 aaaaaataat attttagatt cgagagaaag aagaaaaaaa atattaataa aagatatatc
    34981 aaaaattgta agtgaaaatc ctcaaatgtc tgaaagaaaa ataactgaaa tattaataga
    35041 aaatggatat aatatatcga gaagtgcagt ttcaaaatta ttaaaagagg aaaatttaaa
    35101 tcagtcaaag attgggatta aggataaaga cccagcatca tcaggaaagt atgtgaaggt
    35161 gagtaaagtt gtagaagaag atggatttga agaattgata ggtataaagg gaagtttgaa
    35221 agaaaaggta aatctagcta agtcagcaat aatgtatcct cctaatggcc ttcatactat
    35281 aatatatgga gaaacaggag taggtaaaag tgaattagct acatgtatgt ataaatatgc
    35341 tataaaaaac aacattaaag aagagaacag cccatttata gtgtttaact gtgcagacta
    35401 tgcagaaaat cctaatctat tgatagctca actctttggg gtagtaaaag gtgcatatac
    35461 aggagcagat gcaaatagag aaggtcttgt agaacaagct aataatggaa tattgttttt
    35521 agatgaaatt catagattgc ctgctgctgg gcaagaaatc ttattttcat taatagatag
    35581 aggagaattt agaaggttag gagaaagtag ttctaataga aaggcaaatg ttctcataat
    35641 aagtgctaca acagaaaatc cagattctaa tttacttcaa acatttagaa gacgtatacc
    35701 aatggtaata aatttaccta atatgagtga aagaccaaaa tctgaaagat atgaaataat
    35761 aataaagttt tttgaaagag aagcaaagcg agtaaacaag aattttataa taactaaaga
    35821 agttatgtgt gcacttatga attataagtg tactggaaat ataggtcagt taaagagtga
    35881 tatacaagta acttgtgcta gagcttttag taaatcgata ttttctagcg ataaggtaat
    35941 tatagattta gatagtttaa gggattatat aaaaagtgga tattatgatt gtaattgtaa
    36001 aaatgaaaag tattctgagt tttcagttga ggatatatat atagatatta gtgaattggt
    36061 gagtggaaaa aatagaattt tatctgataa tgagataagc gagatatata attatgcaga
    36121 aaaagagctt aaggttttgg aaagtaagtg cttttcagaa gaagagttaa aaaatgcatt
    36181 tatagaaaag ttagataaga agtttaatgc tattaaaaac aataaaaatt tatctgatag
    36241 aagaagtcga atagactggg gaggacaatt aaaagagtct acactggaga taatggataa
    36301 ggtaattgta tttattaagg agcagtttaa gcatgtaaat caaggtctgt acttggctct
    36361 agcaattcat attgagcatg ctataggtag gataaaagat ggaaaaacta taataaatcc
    36421 gagtttagat aaaataaaag catcaatgcc aatggaatat gagttgtcaa gatatataat
    36481 gggtatagta gaagatttga cacaagtaac atttccagaa gatgagcttg gatatttggc
    36541 ttattatata aataaatttt gttataatga ggaaagtata aaagataaag ttaaagtagt
    36601 aatagttacg catggtaaag ttggaattga aatgtctaaa gttgtaaatc atattttagg
    36661 tatagaatgt acactaggta tagaaatagc acttacagat tcaccatcag aggggataga
    36721 gcatgtatta gaagagcttc aaaagataga agctagaaaa ggtattctag ttctaattga
    36781 tatgggttct ttggtaattc ttggtgatga ggttgaaaaa aggcttggaa ttagatgtaa
    36841 aactgtaaat agagtagata cattattggc aatggaagca ggaaaacttg caaccattga
    36901 aggaaaaagt ttagatggta taatagctga tttaaagaaa aataagaatt atgctatgat
    36961 aaatacaaat aaatttagtt acagaaaaaa cgagtatgga aagaaaaatg taatcattac
    37021 tttatgtttg agtggtgtag gtacagcttt aaatttaaaa gagcatatag aaaaacaaat
    37081 taaggaatat ggcactttaa ttgaagtaaa gccagttgct tttttaaata ataatttaga
    37141 agaagagtta aatgatattg aagctgaata taatattatt gctatctgtg gaactattga
    37201 tatagattat aaaaacgtgc cttttatttc ttataatgag gtacttggta aaaatggtat
    37261 taataaagta ttagagcatc taaatagtaa acaaccagct ttaaatattg aaaaccagtt
    37321 gaataattta atacatgaag atttgatttt atacaatttt gaaggaattt caaaggagta
    37381 tataattgat actcttgttt caaaacttga agaaggtgga tatgttgatt caaagtatat
    37441 attaagtgta tataaaagag aagcaatggg aagtgttgta atggcctcta aggtagccgt
    37501 gccacatgga cttccagaaa acgttataaa gcctgcaata gcaatcgcaa ggttgaataa
    37561 acctatagta tgggacaata aatttatggt ggatttggtg gtactactgg cacttaaaga
    37621 aaataataag aaagaaatac gaagcttatt ttcaaagatt aatgaccagc atactttaga
    37681 agttttatta aatactgaag ataaaaatga aataaaagaa cttttaagct aattattagt
    37741 accgagaaga aagacaaaaa aatttgcttt agtataaaat ttaaaattac tcaattgcta
    37801 agtagttaat tactctatat aaggctagtt ctatgaaatt tatttatatg attttataga
    37861 attagctttt ttcttggtaa ataaaatata tgaatttatt tatgtaaaaa gtaaatttta
    37921 ttggacaatt ctatgaaaat tttt
//
LOCUS       DAMJWO010000038        37917 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.039, whole genome shotgun sequence.
ACCESSION   DAMJWO010000038 DAMJWO010000000
VERSION     DAMJWO010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37917
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.039"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            142..1326
                     /locus_tag="PC366_001915"
     CDS             142..1326
                     /locus_tag="PC366_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577443.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
     gene            complement(1703..2812)
                     /locus_tag="PC366_001916"
     CDS             complement(1703..2812)
                     /locus_tag="PC366_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2577444.1"
                     /translation="MDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEGKDVIAE
                     AQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESKDVSILA
                     AYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQMLLMGF
                     KNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLNNIKQEV
                     VETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLHSDIAQS
                     KRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIGRTGRAG
                     EEGYTCAFIDPKNERMLSEIETAIESKISRRIIEL"
     gene            3275..4468
                     /gene="nifV"
                     /locus_tag="PC366_001917"
     CDS             3275..4468
                     /gene="nifV"
                     /locus_tag="PC366_001917"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HDF2577445.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVI
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            4493..6418
                     /locus_tag="PC366_001918"
     CDS             4493..6418
                     /locus_tag="PC366_001918"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HDF2577446.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREDAWIELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSNVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGSGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            6440..7435
                     /locus_tag="PC366_001919"
     CDS             6440..7435
                     /locus_tag="PC366_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HDF2577447.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGAEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            7762..8235
                     /locus_tag="PC366_001920"
     CDS             7762..8235
                     /locus_tag="PC366_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2577448.1"
                     /translation="MVGSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDEFDKRGYNLT
                     PTDKSLEVYELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            8269..8763
                     /locus_tag="PC366_001921"
     CDS             8269..8763
                     /locus_tag="PC366_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2577449.1"
                     /translation="MIRKANMNDLESIMKIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            8860..9381
                     /locus_tag="PC366_001922"
     CDS             8860..9381
                     /locus_tag="PC366_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2577450.1"
                     /translation="MIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSKGLRTWE
                     FIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAASYIQLQ
                     AHELGLGSCWIQVRNRMYDDNIEADKYIREELKVPSKYSVECIISIGYSDEEKKAYND
                     SDLDYKKVHFNNF"
     gene            9570..9881
                     /locus_tag="PC366_001923"
     CDS             9570..9881
                     /locus_tag="PC366_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2577451.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            9909..10595
                     /locus_tag="PC366_001924"
     CDS             9909..10595
                     /locus_tag="PC366_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2577452.1"
                     /translation="MKYSYKKCIIDSILLMFIIQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLSLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
     gene            10827..11711
                     /locus_tag="PC366_001925"
     CDS             10827..11711
                     /locus_tag="PC366_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HDF2577453.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSV
                     VNGEVRQNSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
     gene            11810..12985
                     /locus_tag="PC366_001926"
     CDS             11810..12985
                     /locus_tag="PC366_001926"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HDF2577454.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEELLKDIPTANKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            13113..13967
                     /locus_tag="PC366_001927"
     CDS             13113..13967
                     /locus_tag="PC366_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577455.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSNESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKEGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKIKDDSSC
                     LYLDIYND"
     gene            14011..15246
                     /locus_tag="PC366_001928"
     CDS             14011..15246
                     /locus_tag="PC366_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDF2577456.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREIVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSESKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKSISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYISLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNEKTSVDMSKKTW
                     DGLAYRINEVILMDELCLV"
     gene            15347..16288
                     /locus_tag="PC366_001929"
     CDS             15347..16288
                     /locus_tag="PC366_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HDF2577457.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAIGISDKSIIEQCLDAVKK"
     gene            complement(16517..16870)
                     /locus_tag="PC366_001930"
     CDS             complement(16517..16870)
                     /locus_tag="PC366_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDF2577458.1"
                     /translation="MDRKRELKQLYKEMKFDTGVFIIKNDITKKIYLGKSNDIKSKFN
                     SLKFQLGAGSCMIKELNNEWKKYGEKAFTFEVLELIKHDDNKTEKDYLEELDILEMIW
                     LEKLKEDNTYEIYSI"
     gene            17166..18077
                     /locus_tag="PC366_001931"
     CDS             17166..18077
                     /locus_tag="PC366_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HDF2577459.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLEFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            18337..18771
                     /locus_tag="PC366_001932"
     CDS             18337..18771
                     /locus_tag="PC366_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577460.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEILGEFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            18794..20329
                     /locus_tag="PC366_001933"
     CDS             18794..20329
                     /locus_tag="PC366_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577461.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EISLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVKNYIESIDIENRFCNLFKKKDREKLFYDYGVIYK
                     IDCDVILVNLFELIINNCIFSTILGNEVINLEISKYEYEFLEKQFKNMYNNITEDKVI
                     GSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRINKKITLLLMEAIEVLIKRL
                     SIEDEDVIRYIKKYEKIFIESVLSSIKSNTFKSMVTVSKNKNEHLEDYIVDDESKLDD
                     ESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESECLFGEEYLMLFASLSELE
                     LAILGSVVFYEDIRMREINILEFMLNEKTETTLWKTEYIKFMKRQSEDKIYSIEEHMN
                     KIN"
     gene            20413..21780
                     /locus_tag="PC366_001934"
     CDS             20413..21780
                     /locus_tag="PC366_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2577462.1"
                     /translation="MKEYIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTVMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKARDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFVGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPV
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMNTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            21815..22039
                     /locus_tag="PC366_001935"
     CDS             21815..22039
                     /locus_tag="PC366_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HDF2577463.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGATMTIKAIIENVLVSEVPGVTQVLGV"
     gene            complement(22489..22887)
                     /locus_tag="PC366_001936"
     CDS             complement(22489..22887)
                     /locus_tag="PC366_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03987 family protein"
                     /protein_id="HDF2577464.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMVG"
     gene            complement(22890..23291)
                     /locus_tag="PC366_001937"
     CDS             complement(22890..23291)
                     /locus_tag="PC366_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2577465.1"
                     /translation="MLLKELYSKTMYTVEENFKENGLTHQQIIVIKLVAHNQELTISQ
                     LCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFEFATNFKIKMQE
                     SFDDIFKNCDENELSDLVKNLRNILAKVKER"
     gene            23650..24636
                     /locus_tag="PC366_001938"
     CDS             23650..24636
                     /locus_tag="PC366_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577466.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLNEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
     gene            24620..25531
                     /locus_tag="PC366_001939"
     CDS             24620..25531
                     /locus_tag="PC366_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577467.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEHIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIRNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            25644..27212
                     /locus_tag="PC366_001940"
     CDS             25644..27212
                     /locus_tag="PC366_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2577468.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHVLEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGIFWNIADWTIE"
     gene            27287..28312
                     /locus_tag="PC366_001941"
     CDS             27287..28312
                     /locus_tag="PC366_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577469.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDEYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            28305..29249
                     /locus_tag="PC366_001942"
     CDS             28305..29249
                     /locus_tag="PC366_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009527644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577470.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKSLSWIEVSDGHFVYSSKSEINKYQQNLKVV"
     gene            29608..31266
                     /locus_tag="PC366_001943"
     CDS             29608..31266
                     /locus_tag="PC366_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2577471.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERDSKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAVNTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASNGKSSW"
     gene            31247..32263
                     /locus_tag="PC366_001944"
     CDS             31247..32263
                     /locus_tag="PC366_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2577472.1"
                     /translation="MVKAVGDIIGKCSAISFDMKLDKSYDEVIVDFKNLINNIDNKDV
                     LLFTDMGSLNSFDEIIKKEKKCEVRVIPMVTTLTVLEAVQKANMGLPLNDVYNSITNT
                     RKYYFGTNEIQNKENLSKTIIIASHVSEGVDNKTRKILEEKMSRYLDGIDIISVPYKT
                     EKDLSLNITKLKESSNIVAVINEQRINIRGIDYISKKDIDKDENINKLKNIIKISIGY
                     DDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLVFNIEKKYDKVIGLMMHLAFMVDGLI
                     GNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDKKYNIEINEKECYQILLILEYAEIIE
                     KDYQ"
     gene            32478..33107
                     /locus_tag="PC366_001945"
     CDS             32478..33107
                     /locus_tag="PC366_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577473.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            33242..33568
                     /locus_tag="PC366_001946"
     CDS             33242..33568
                     /locus_tag="PC366_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2577474.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            33584..34873
                     /locus_tag="PC366_001947"
     CDS             33584..34873
                     /locus_tag="PC366_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2577475.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            34897..35226
                     /locus_tag="PC366_001948"
     CDS             34897..35226
                     /locus_tag="PC366_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDF2577476.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKHHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            35374..36702
                     /locus_tag="PC366_001949"
     CDS             35374..36702
                     /locus_tag="PC366_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDF2577477.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            37019..37879
                     /locus_tag="PC366_001950"
     CDS             37019..37879
                     /locus_tag="PC366_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HDF2577478.1"
                     /translation="MAMKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKE
                     VPSKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDI
                     EEVEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCD
                     KIIKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLN
                     TIKEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEE
                     EEEKYRRIFK"
BASE COUNT        14972 a         3961 c         6788 g        12196 t
ORIGIN      
        1 tttaatacaa aggtagaaat aagttgaaaa tgtaaagtca ttggaaaaat atagttgaat
       61 ttaatgaaca aaaatgttat tgttttatca atgaagtgtt aaaataaaaa ctttcaatat
      121 cattttaggg aggatgattt catgcaaaaa agtgtaaaga aagcaaaagt aacgggatct
      181 atgttagcca tttttggtgt tgcaagcgtt ctttttagtt cacatgcagg aggaggattt
      241 gctacaggga atcaagaaac tcagtactat gtgcagtatg gatggacagc accacttatg
      301 gcaattttag caatgattat acttactgct accatgagag aagttatcat aatgtataat
      361 aataacaatt gtaggaatta taaggattta ttttgtgagc tttggagacc atatccaaaa
      421 cttgaaataa tatgggagat atattactat ctaatggttt taatagctgt aagtgctgtt
      481 atagcaggtg cagcagcagt atttcaaagt ataggagtaa attattttgt agctgtattt
      541 attattggag ttgtacttct tgtctttact atatttggtg ctatgcttgt atctaaagca
      601 gctacagcaa tgacaatagc tattctagta tgtactctta ctatttttat tgttggtata
      661 aaagctaaag taccagaaat aactgaaata ttatcaaata gaacgagttt cacacctggc
      721 tatatcaagc caatacttaa tacttttatt tatgcaggtt ttcaatcggt tgttatacct
      781 acacttgcag gatgttcaag accacttctt aagaactcaa aagaagctac taaggcaatg
      841 ataatttcat ttgttatgaa tgcaattgca ttaggacttg ctgtaactat gctaatggga
      901 tggtatagag aaattattgc tgctgggcaa acaacactcc ctactcttta tgttgcaggt
      961 caatctggaa atcatactat atacataatt tataatgttg cattattcct ttgtttaatg
     1021 tctacaggag taactactat atttggtctt gtaaatagat ttgaagacca taaagcactt
     1081 tctttccttt cttcaagaat gaaaagaagg gtatttacag cttgtgcaat aatggtagtg
     1141 tcaatgctta tatcacttac aggattaagt aatattgtta aatatggata tggatattgt
     1201 ggttatcttg gtctattcac tatagtaatt ccattcctta cactaggaca ttataagaat
     1261 aagaagtttg caaaggaaaa tccagaagct aaatggccag cggaattaaa tgaaaatgta
     1321 aattagatgt agtagcaaaa aatattgcta aagagaatac tataaataag aatactatag
     1381 ataatatatc tgcatgttta ttaagattat ttgcaaaatc taatattgaa caactataaa
     1441 caagcaatat aaaactaaga ataaaagata aaaagagggt gtctcaaaat ggacttttag
     1501 tttataaggc actctttttt atatgaagtc aaatatattt tcattatttt gacaataaaa
     1561 gagactaatc ctactttgga tagcctcttt tttctttaat ataaaatagt ataacagcaa
     1621 agtatagatt gatacatgtt ttctgtagct ttctatatat tacagtgttt gtgtggcatt
     1681 ggtattttaa gcaatctata aattataatt ctataattct tctactaatt ttagattcta
     1741 tagccgtctc tatttcactt aacattcgtt catttttagg gtcaataaaa gcacatgtat
     1801 agccttcttc accagctcta ccagttctac caatacggtg gatgtagtct tctggtgttt
     1861 ctggtaaatc gtaattatat atatgactta ctccagatat atcaaggcca cgagaagcta
     1921 catctgtagc tattaagtat tgtatatcta aatttctaaa tgatttcatt attctttctc
     1981 gttttgattg agcaatatca ctatgaagtt tttgacaatt atatcctctt atagcaagag
     2041 cttcttcaag attgtcaacc cttctcttag tcctacaaaa tattattgcc ataaaaggat
     2101 tatcttcatc tagtacctta cataaggcat ctaatttttt tctatctgta gtttctacta
     2161 cttcttgttt tatattatta agagtgattt cttctttttg aatagaaact acaacaggat
     2221 tttttgtgta tctataagct aattttttta cttgagaatt tatagttgca gaaaagcata
     2281 gtgtttgctt tttgtttgaa gtctctttta aaatagcttc cacttcgttt ttaaatccca
     2341 taagcaacat ttggtctgct tcatctaaaa caaaagtctt taacttacta aggtctattg
     2401 tttttctatt tagatggtct aaaagcctac ctggtgtagc tataatcata tgaatatttc
     2461 cttttagttt ctttatttga gaaccaatat cttttcctcc atatgctgca agaatactta
     2521 catctttaga ttctttaagt ttcatagctt cttctgttat ttgaatagct agttctcttg
     2581 taggagaaag tataagtact tgtatatcat ttatatctaa tgatatattt tcaaatatcg
     2641 gaagtaaaaa agctagtgtt tttcctgttc cagtttgagc ttctgctatt acatcttttc
     2701 cttcttttat tagtttaata ctttcttttt gtataggtgt aggtgttgtt attcctgatt
     2761 tttttagaat atttattgta ttttcactaa tccctaagct tttgaaatcc attgttatct
     2821 tacctttcat gaaaaatttt cttttttatt aaccaattaa taatatcata tttgtaagta
     2881 tttttagtaa attttttaat tattatttat atagcttaaa aatatattaa gatactttaa
     2941 aatggaatgt aacttaactt aaattttagt aggaatttta taggtttatt tttaaaggtt
     3001 ttttgaaaat aaatctattt aaaaattaaa ttaaaatgca agaaaaacat aataactttc
     3061 atttttaaga agttttcaca aaaaagaaaa aatatagtgc aataaatgat acaaagtaat
     3121 ataatagatt acaagatatg aaaagctaaa aaaataaatt gcaaatgaaa ttaaaatgaa
     3181 taaaaaataa aaaaataatc ataagttaga ggtatcaatg aaaaataaga cttaatgttt
     3241 ttaaaattaa aagtatacta aggggggcat taatatgtgc gttatatcaa aagatagagc
     3301 aaaggaaata aaaatagtag atactacttt aagagatgga gagcaaacag ctggggttgt
     3361 atttgcaaat agagaaaaaa taatgattgc tgaaatgtta agtgacctag gtgttgacca
     3421 aattgaagtt ggtataccta ctatgggtgg agatgaaaaa aatgtaataa agcacatatg
     3481 tagtagaaat ttaaaatcag atataatggc ttggaataga gcagtaataa aagatgttga
     3541 agaatctatt tcttgtggtg ttgatgcagt agctatatca atatcagtat ctgacattca
     3601 tatagaaaat aaattgagaa cttctagagg ctgggtttta gaaaatatgg ctaaaacagt
     3661 tgaatttgca aagaaaaatg gattatatgt ttcagtaaat ggagaagatg cttcaagagc
     3721 agatatagac ttcttaactg aatttataaa tgttggaaaa caagcagggg cagatagatt
     3781 tagatactgt gatacagtag gagttatgaa tcctttttct ataaagaatg caatagaaac
     3841 tctttatgaa agaactaatt ttgatataga aatgcataca cataatgact ttgggatggc
     3901 aactgcaaat gcacttgcag gaatagcagc aggagcaaat tatgttggtg ttacagtaaa
     3961 tggattaggt gaaagagcag gaaatgcagc attagaagaa gttttaatgg cacttaagtg
     4021 tgtttataaa tgtgatttaa ataatataga tactagaaaa tttagaggaa tatgtgagta
     4081 tgtagcacag gcatcaggaa gaatacttcc tacatggaaa ccagtagttg gggataatat
     4141 gtttatacat gaatctggta tacatgcaga tggagcttta aaagacccgc ataactatga
     4201 accatttgac ccaagtgaag taaatcttga aagaaaaata gtaataggta aacattcagg
     4261 aagagctgca gttataaata agttgagtga atatgaaatg tatatttctc cagaaaacgc
     4321 taccaagcta ttaaatgcta taagagctac atctataaga ttaaaaagaa gtttaatgga
     4381 taaagaaatt cttcaattat attgtgatat actagcacat gagaaaggca caacagaaga
     4441 agaagcagtt agaggttcat atatttaaga tataattgtt taggaggaaa atatgggaga
     4501 taatatagtt tataaaataa ttaaaaaaca tatagtagat ggagaagctg ttgctggaag
     4561 ttcaattggt ataaaaatag accaaacttt aacacaagat tctactggaa caatgacata
     4621 tcttcaacta gaagctatgg gaatagataa agtaaagact aaaagaagtg tggcatttgt
     4681 agaccataat atgttacaac aaggatttga aaatgcagac gaccataagt atatacaaac
     4741 agtggcagat aaatatggag tttatttctc taagccagga aatggtattt gtcatcaagt
     4801 atttttagaa agattttcaa caccaggaga tacactttta ggttctgata gccacacacc
     4861 tactgctgga ggtgtgggca tgatggctat tggagctggt ggattagatg ttgctttagc
     4921 catggcagga ggagcatact atataaaagc accaaaagtc tgtaaggtga atctagttgg
     4981 aaaattaaat aatatggtat catcaaaaga tataatatta gaagtgttaa gaaaacaaac
     5041 tgtaaaaggt ggagtaggta aagtttatga atatggtgga gaaggtgtca aaagcctatc
     5101 tgttccacaa agagctacaa taacaaatat gggggctgaa cttggagcaa ctacttcaat
     5161 cttcccaagt gatgaaaaaa cactagaatt ttttaagagt caaggaagag aagacgcatg
     5221 gatagagtta aaaccagatg cagatgcagt ttatgatgaa gagattacta taaacttgga
     5281 tgaattaaaa ccattagctg caaaacctca tagcccagac aatgtagatg aagttgaaaa
     5341 tataggcaag attaaaatag accaagtggc aataggaagt tgtacaaatt cttcttatga
     5401 agacttaatg aaagtagcac aaatcctgaa aggaaataaa gtacataagg atgtgagttt
     5461 ggtaatagca ccaggttcaa gacaagttat ggagatgatt gctagaaatg gggctttggc
     5521 agatataata agtgctggag ctagaatact agaaaattct tgtggtccat gtattggtat
     5581 gggtcaatct ccaggtactg actctgtgtc tttaagaact ttcaatagaa atttctatgg
     5641 tagaagtggg actttgtcag cacaagtata tttagtaagt ccagaagtgg cagcagtaag
     5701 tgcaatcaag ggagtgctta cagacccaag agaatttgat attaaattta caaatttaga
     5761 tgtaaatgaa tttttgatag atgatagcat gataattaaa cctgctgatg taggaagtaa
     5821 tgtagaagta gttagaggac ctaatataaa acctttccct cttaatacag agctaagtca
     5881 gtctataggt ggaaaagtta tattaaagac agaagataat ataactactg accatataat
     5941 gccatcaaat gctaagttac ttccttttag aagtaatata ccgtatcttg caaactattg
     6001 tttcaatact gtagatacag aatttcctca gagagcaaaa gacaataatg gtggatttat
     6061 agttggtgga gataattatg gtcaaggttc aagtagagaa catgcagctt tagcaccatt
     6121 atatctaggt gttaaagggg taatagttaa gagctttgca agaatccaca aggctaactt
     6181 gataaatagt ggtataattc caatggagtt ttgtgatgag aaagattatg aaaatatatc
     6241 tcttttagat aatctggaga taccaaatat tttagacaat ctaggtagtg gaattttaga
     6301 agttaagaat acaactaaag gaacttcttt taaggtcaaa gtagaattgt cagcaaaaga
     6361 agttgacgta ttaaaagctg gtggaaaatt aaactacact aaaaatcaag ctaattaata
     6421 tgaaaagagg gaatattgaa tgtataaagt gacacttata ccaggagatg gaataggacc
     6481 agaagttgcg aaagctatga aaaaggtagt agaagctact ggagcagaaa tagaatggga
     6541 agaagttaat gcaggagagg cagttattga agagtatggt actccacttc ctgaatatat
     6601 tatagatagt ataaaaaaga acaaaatagc tataaaaggc ccaattacta ctcctgtagg
     6661 taaaggattt aggagtgtaa atgtaacttt aagacaggca ttagatttgt atgtcaattt
     6721 aagacctatt aaaagtttta aggggataaa atcaagatat gaagatgttg atttagtggt
     6781 tgtaagagaa aatacagaag atttatatgc tggaatagaa cataaaatag gtgattatgc
     6841 agctgaaagt ataaagataa taacaagaag tgcaagtgaa agaatcgttg attttgcatg
     6901 taactatgtt aaagataata agagaaaaaa agttacagct atacataagg caaatataat
     6961 gaaaatgtct gatggattgt ttttagatgt gtttagagaa gttgcatcaa aacatggtgt
     7021 agaatatgat gatttgattg tagatgcagc agctatgaac ttagttttaa atccagaaaa
     7081 ttatgatgta atggtaatgc caaatcttta tggagatata ctatcagatt taggtgctgg
     7141 gcttgttgga ggtttaggta taattccaag cgcaaatatt ggtaaagatt gtgcgatatt
     7201 tgaagctgtt catggaagtg ctccacaaat agcaggtcaa aataaggcta atccaacagc
     7261 acttattcaa tcatcagtaa tgatgcttag atacttaggt gaatatgaaa atgcacaaaa
     7321 aatagaaaca gctttagaaa aagtatttct tgaaggaagt aaattgactg tagatttagg
     7381 tggctcagct tctactacag agtttgcgga tgaggtgtgt aagtatattg tatagatttt
     7441 atttagggaa aaagtgaaat atagattgaa ggaaagaggc tttctcaaaa tagagataag
     7501 ccttttttta ttggaatgat aaaatatatt tgattttata caaaagagag ttcctcataa
     7561 acgaaaaagt taattttggg atatccattt taattttaaa attaattgat taatacgcaa
     7621 agaaagatta aacaaattta ttatttttaa ttgaactttc aaccaaaata tggtaaaatt
     7681 taaaaaagtt gaactttcaa ctaaaaataa atatattgat tatgtgaaat tctataaaac
     7741 agaaactatt tgactttagt catggtaggt tcagtggagg tgtgtttgat taagacttta
     7801 gatagtaata tattaagaga agtaggtact ttatctagag cagtaaattc aataaatgat
     7861 attaagtaca aggaattaaa gttacaaaaa ggacaattta catttttgac aagaatctgt
     7921 gaaaatcctg gtataaatct tgtggaatta tcaaatatgt taaaggtaga caaggctaca
     7981 acaaccaagg ctatacaaaa actaataaag gcaggatatg tagataaaaa gcaggatgag
     8041 tttgataaaa gaggatataa tttaactcca actgataaat ctttggaagt ttatgagttg
     8101 ataattgaag aagagaatag aagtatagag atatgttttg ataattttac agatgaagaa
     8161 aaacaagtgg taactaagtt attagaaaaa atgagcaaaa acgtagaaaa tgaatggttt
     8221 aaagtaaaga gatagtaaat aaatacatta acttaaggag atatttttat gattagaaaa
     8281 gcgaatatga atgatttaga aagcattatg aaaattataa aatctacagt ggaagaaatg
     8341 aagacttata ataatacaca atgggatgaa aactatccat tagaaaaaga ctttgtttca
     8401 gatattaaga aacaagattt atatatttat gaagtggatg gagaagtagc aggatttata
     8461 tgtcttaatt atgaagagcc agaagaatat ttaggcttaa attggtcatc taataaaaaa
     8521 gcaatggtaa tacatagaat ggctgtaaat ccaaacttta gaaagacagg aatagcatct
     8581 aagttagttg attttgctga aaaattagct gtagaaaaca atgtatcata cttaaagagc
     8641 gatacatatt caataaactc aaaaatgaat ttattactta caaagtgtgg ttttataaaa
     8701 atcggagaaa tgagtttttt aggaaaggag aaatctttct actgttatga taaaatatta
     8761 taaagagcat ttataataca aggggtaaat aatagatttt cagcattagt aagggcataa
     8821 tataacccag tatatgctat tatgaaaggg atgatttata tgattggatt tctaaagaaa
     8881 agaagaagta ttagaaaata caaggatgtt gaagtagaaa aagaaaaatt agataaaata
     8941 ttaaaagctg ctcttttagc tccatcatca aaggggctta gaacatggga atttatagtg
     9001 gtagatgata aagaaaagct aattaattta tctcaatgta gaactaaggg tggtggattt
     9061 ttcttaaaaa atgcaccttt agctattgta attattgcag ataaagaaaa aaatgatgtt
     9121 tggatagagg atgcaagtat agctgcttca tacatacaac ttcaagctca tgaactaggt
     9181 ttaggttctt gttggataca agtaagaaat agaatgtatg atgataatat agaagctgat
     9241 aagtacatta gagaagaatt aaaagtacct agcaagtaca gtgtagaatg tataatttct
     9301 ataggatatt ctgatgaaga aaagaaagca tacaatgact ctgatttaga ctataaaaag
     9361 gttcatttta acaactttta gtatataata tgttgtatta agacattata tttttttcta
     9421 ttgttaatat atacttaaaa ttgtaaaaat atatctgaat tttactaact tatctagggg
     9481 ttatgtacaa ggattttaaa gataaatata gaaattaatg tttataatcg atacataact
     9541 tgagtaacaa aatttaagga ggttaaagta tgggtatatt taaaacaaaa atggatgagg
     9601 actggaaagt aaactacatt aaagagttta atgaaatgag agattcttat gagagtaaac
     9661 ttcaaaaaaa acagtttgag gtagatagtt tgaaatcaga attggataga ctaagaagct
     9721 ataaaaatag ccttaagcca aaagaaaaac aaattactga tgatgatata aataatataa
     9781 agagtttaag aagagatggc ttaagctata aagaaatttc aaatcaaaca agttggagca
     9841 aagcaactgt aagtagggta ttaaatggac tttacgatta gcatatacat ggggtgattt
     9901 aaattgggat gaagtatagt tacaaaaaat gcataataga ttctatttta ttgatgttta
     9961 taattcaaat attaaggatg attttgaatt atgtacttct aagtcaattt gaatttactc
    10021 ttgaaaattt taatattata aacttaattt cttttacatt agttggttta tcgttaattt
    10081 tatttttaaa agataattct ttgtataaca aggttagaaa tagaaaaatc acagaagctt
    10141 ttgaagaaaa taaaaacaat atacttattg aaaagtgtaa gcttatactt tttgttgtgg
    10201 ttttatcttt agcaataatt gtaacttatt gtactaaggg atatgtactt tttaatgtaa
    10261 ctatgatgac tttgtctgta ttgatagttc caatatttga agagttattt tttagagaat
    10321 atatatggaa ctatctaagt aattttataa agtcaaagag taaaattatc tgtataacat
    10381 ctatactatc tggaatttat aatataggat acatagatgt tataagaaat tatgtaatat
    10441 tgtataacaa ttcaagctac acctttgaag ttattatttc aaaaattatg ataggtactg
    10501 tttttggtat tgtacttgga ttagttaagt ataggtttag agatgtaggg ttttgtatat
    10561 tattgaggag cttatttgct atatttatta ggtagatagt ataatcggtt tataaggttg
    10621 ttttaaattt aattttaaat caaccttatt ttatttgtgt tttataaaac acttatatat
    10681 taataactaa taaatttaat aaagattatt tgaatatttt taaaatatat aaatatgtat
    10741 tgacatataa atattatgaa ttacaattta tataaactaa taaaaattaa ataatattaa
    10801 tcaacttatt gaatggagga ataaaaatga aatttgtgac tttttgtagt agcaatgaag
    10861 aaaaaatagg tgtatttaat tcagaaacaa atagtatata tgaaattaat agtttaggat
    10921 taagtaaatt atatactgat atgaatgatt ttattgaaaa cgtatctaca ggagatttag
    10981 aaaaaataaa aaacaattca tttgaaaacg caaagtgtta taagttagaa gaagttaaat
    11041 tatgttcccc aattgtaaga cctaaaaaag atattatatg tttaggtcta aactataaag
    11101 accatgtcaa tgaaatccca gatggagtta taaaaaacgt agttatgcca gattatccaa
    11161 tttatttttc taagagagca gacaaaataa ttggagtgga tgataagata agcttacatg
    11221 gagatttggt agagaagttg gactatgaat cagaacttgc agtaatcata ggtaaagaag
    11281 gtataaatat atcaaaagaa gatgcttatg aatatatatt tggatataca atagtaaatg
    11341 atataagtga aagagcactt caagataaac atgttcaatg gtttagagga aaaagcttag
    11401 acacacatac atctatggga ccttgtatag tacataaaga agaatttgaa catcctttaa
    11461 aattagatat aagtagtgta gtaaatggag aagtaagaca aaattctaat acagagtact
    11521 ttatatttga tatacctact ataataaatg atttatcaag aggaatgact ctaaagccag
    11581 gagatataat ttcaactgga actccagcag gggttgctat ggggatgaat cctcaagtat
    11641 atttaaagca tggcgatata gttgaatgta aagtcgaagg aataggagtt ttaaaaaata
    11701 tagttgatta atggataaat atgccatata attttattag tacaaataat ttaattaata
    11761 taggattgat caaacttatg attaatttat tatagagagg gatgagtata tggcaagaga
    11821 actagaatta aagtatggct gtaatccaaa tcaaaaacca tcaaagattt atatgaagaa
    11881 tggagaactt cctatagaag tattaaatgg aaaacctgga tatataaatt ttttagatgc
    11941 atttaatagt tggcaacttg tgaaggaatt aaaagaagct acaggtcttc cagcagcaac
    12001 ttcatttaaa catgtaagtc cagcaggagc agcagtaggg gtacctttat cagatacttt
    12061 aaagcaaata tattttgttg atgatttaga gctttctcca ttagcttgtg cttatgcaat
    12121 ggcaagagga gcagatagaa tgtcttctta tggtgatttt atagcacttt cagatgtatg
    12181 tgataaggag actgcaacta ttatagcaag agaggtttct gatggtataa tagctccagg
    12241 atatacagat gaagcccttg aaatattaaa aggaaaacgt aaaggcaact ataatattgt
    12301 aaaaatagat gaaaattata ctcctgagcc tattgaaaca aaggatgttt atggaattac
    12361 ttttgaacaa ggtagaaatg aaatattaat aaatgaagaa ctattaaaag atattccaac
    12421 tgcgaataaa atttttacag atagtgcaaa acgtgattta attatagctc ttattacatt
    12481 aaaatataca caatcaaatt ctgtttgtta tgctaaagat ggacaagtaa taggggtagg
    12541 tgcaggtcaa caatcacgta ttcattgtac tagacttgca ggtaacaaag ctgatacttg
    12601 gtatcttcgt caacatccta aagtattaaa cttaaaattt aaaaaggata taggtcgtcc
    12661 agatagagat aacactattg atgtatatct ttctgatgat tatatggatg tgcttgctga
    12721 tggcatatgg caaaactttt ttgaagaaaa accagagcct ctaactggag aaggaaaaag
    12781 agcatggctt aaaactttaa caggagtagc acttggttca gatgcatttt tcccatttgg
    12841 agataatata gaacgtgcaa aaagaagtgg ggtaagtttt atagcacaac caggtggttc
    12901 tattcgtgat gataatgtta tattaacttg taataagtat aacatagtca tggcatttac
    12961 taaaaataga ttattccatc attaaaatac tgaaagtata aagataatat agattaagta
    13021 aaaatctaca acaagttttg ttgtagattt ttttatttgc tgtataattt taaatagaac
    13081 tttattttta gatattcaat ttggaggttg atatggcttt aaatataaga aactatagcc
    13141 tattatgtaa tcaaggaaca gctaaattta atgaagatgt agtcggtata aatccatttg
    13201 gggcatgggt tttagatggt gctacaggac ttaatggaaa aaatttagtg tcaaatgaaa
    13261 gtgacgcaag gtggtatgtt cagtggtgga ataggtattt atataaaaat ataaataaag
    13321 aagaatcatt aaagagtatt attaatactg gaataataga agtaaaaaaa gagtatgaac
    13381 taagattaaa tgggtttaag gttgaaaaat tagatttacc atctagttct atagttgttg
    13441 taaaatttca tgaaaataaa gtagagtatt ttttattagg agattgtgct ttgtttatta
    13501 aaaatggaga ttccaaagtt ataaaagata ggagtatttg taaatttgat aatactgtat
    13561 ttgatgaaat gagtaaactt tctaacttgg aagagatggc atttgatgag attagaacta
    13621 gtgttatgga tacaatagta agcaatagat tgaagaaaaa tacgaaagag ggctattgga
    13681 tattggattt tgatgaggaa gctgtggaaa attctatata tggatacatt gaaataaaaa
    13741 aagattttca attgatgcta acgagtgatg gttttacaag tgcatgtgat agatataatc
    13801 taataaaaga agaagaattg atacgtatag cagaaaaatt tggtatagga tatatacata
    13861 ataaagtaag ggattttgaa gataatgact ataaagcggt taaagtgcca agatttaaaa
    13921 taaaagatga ttcatcttgt ttatatttag atatatataa tgattagact gtataaaact
    13981 atttaatttt agaaaggagg caagtgaaaa gtgaaaattc ttcatataat aacacaaaaa
    14041 ccaaatagta caggtagtgg tatatatttg tctggtatga taaaagggtt cgaaaaaatc
    14101 ggtcataagc aagctgtaat tgcaggtata gatgtaaatg atgatgtaaa ttgttttcca
    14161 agtgaagtaa gtttttatcc agtaaagtat aattgtgggg agttaaattt tcctgttgta
    14221 ggtatgagtg attctatgcc atatgaaagt acaagatata aagatttaaa tatagacatg
    14281 ataaatagat tgaaatatca atttaaagta aatatagata aggctatgaa tgattttaaa
    14341 ccagaactta taatatgtca tcatttgtac ctcttaactg catttgttag ggaaatagta
    14401 aaagatataa aggttatgtc tatttgtcat ggaacttgtt taagacagtt aaataccatt
    14461 gatttagaga aagaatacat aatagcaaat ataaggaaat tagatttaat atttgctctt
    14521 catgaaaatc agaaatatga tattataaag acttttggag taagtgaaag taaagtagtt
    14581 gtaattggta gtggttataa tgatgatata ttttataata aaaattataa aataaaggat
    14641 gataaaataa aaatagtatt tgcaggtaag atatgtaaat caaagggatt gattccattt
    14701 ataaaatcta tatctaaatt aaaatatagt aaagatttaa tagaagtcaa ttttgcaggt
    14761 actggaagcg atatcgaatc atataatgag atagttaaac tggcaagtaa gtctccattt
    14821 aaaatgaatt tcctaggaaa gttagaacag agagatttag ctgagctatt caacaggtca
    14881 caaatatttg tgttaccatc attttatgag ggattaccag ttgtagtttt agaagcttta
    14941 tcttgtggca cagatgtaat cactactgat attcttggtg ttaaagagtg gattggtagt
    15001 gagattaata attctggaaa gatagaatat atttctctac cttttatgga gaaagaaggt
    15061 attccaaaag atgaagagtt atatgatttt gaaaataatt tgtataatgc aatagattct
    15121 aagatacaat ctttattgaa taactcaaat gagaaaacat ctgtagatat gtcaaaaaaa
    15181 acgtgggatg gcttagcata tagaataaat gaagttattt taatggatga attgtgttta
    15241 gtctaaaatt atttaaatta taaaaaagtg taactatttt taaacttttt ttaaatgatt
    15301 ttatattata ctaatactaa atatatttgt tttagggagg taatttatga ggattagtaa
    15361 aaaggtattg gcgttaggta tttcagcatt actgttaagt gttagttttc caacatcaat
    15421 aaacgcacta gataagattg aaaatattca aggagtagat aaatatgaaa cagctgggct
    15481 tatttcagat aagcaagatt ttacaacagc agttcttatc aatgcagatt ctacaatggt
    15541 agatgggatt gctgcaagtg gtcttgcagg agtaaataat gcagctattt tattaactaa
    15601 taaggatgat ataccagaag caacacttca aagactgaat agagttacta agatatatgt
    15661 aataggtgga gaaaattcta taagtaaaga tgtagaaaaa atgttactta tgagaagaat
    15721 gcaagttata agaattgatg gtgtagatag agtagataca agttataaaa ttgcaggtga
    15781 aatagaaaaa attaaaaaca gtgataagat gtttttagta aatggattta aggatgaagc
    15841 tgatgcagta agtgttgcat ctgttgctta tagagatgga gctcctataa tattgacaaa
    15901 agatatacct tcagcagaag aagacacaga cttagaccca tggtttggag tttctcctgt
    15961 tccagtatat gctattggag gagagtctac attaagtgat tacatagtga gcagatatag
    16021 agcaactaga attggcggtg ttgatagata tcaaactaat aaaaatgtta ttgaaaagtt
    16081 ctataatgga gcaaaagagt tctatataac aagtggagac gatttagttt atgctttagt
    16141 tgcatcacca cttgcaaaaa atgctcctgt tgttttagtt tcaaataaaa gtgataagag
    16201 tatattaagt ggagctagta aagtaacagc aataggtata agtgataaga gtattataga
    16261 gcaatgtttg gatgctgtaa agaagtaatg gagtgttatt agtaaaatga atatatacat
    16321 tgaaaattag tagattgttc attttataat ggtataaaat atatgggaag aggctatcaa
    16381 atggagataa gcctcttttt tattgataaa attatgaaaa tatactttat tttatataaa
    16441 aaaagtatct catgaactaa atgtctattt tgatatacta tctccttttc ttatattata
    16501 tgtattatat gattttttat atggaataaa tttcataagt attatcttcc tttaattttt
    16561 ctaaccaaat catctctaaa atatctagtt cttctaaata gtctttctct gttttgttat
    16621 catcatgttt tataagttct aaaacttcaa atgtaaatgc tttttcacca tattttttcc
    16681 attcattatt taattctttt atcatacatg agccagcacc aagctgaaat ttgagagagt
    16741 taaatttgct ttttatgtca ttactttttc caaggtaaat ctttttagta atatcatttt
    16801 ttattatgaa tacacctgtg tcaaatttca tttctttgta taattgtttt aattcacgtt
    16861 ttctatccat gattttagat acctctcttt ataattgata tgtaatatgt aagtttaaaa
    16921 atatattaca tatcaattat aaagagatta attttatatg taaatagttt ttataaattt
    16981 aattatgaat tagtcatcaa taaacaagaa atttagctgt agaaatccat tataaaggct
    17041 attataaatt ttaatatgct aaaaatataa aaagaatagt tgacagtata gaaaatatgg
    17101 aataaactaa aagtgtaata gtaatacgaa attatatatt acattgaaag gtgtgaatga
    17161 ttattatgaa taaaaaaata gaattaatag ggaattttgc aagtgattgg attaggtata
    17221 gtgattatga atataaaatt actgaagaag atgaattata tatagttcca acagaagatg
    17281 ctgtgtttac catgtataac ccatttgatg tagcagatga tataatagta gatataattc
    17341 gcataggaca agaggcatta caagatatat caaaagagac aaaagaaatg aaactaaaga
    17401 aagaagtact tgaatttgta aaaaagtatg gattattggg tttaatatat tcaagtgtat
    17461 ataatagaga tatagttgga gaagaaagag tactgatgat tgaaaagaat tatattacaa
    17521 aagagaatat attgagtaca gatgaatatg taaacatgtt tataccattt gcaagtgatg
    17581 aagatgtgta ttttaaaaaa tatagaaggg gtatagatgt atcaaagaga gaagaatctc
    17641 caaagttttt tggaaagaga ccattgattt tagatttagt attttcaaag ttctacactg
    17701 aacaactaga ttggattgta agttttgcta aagatatgtg taagcatttt aatcaaattt
    17761 gtgtatataa aaatacatct aatctattaa ctgaaagtgt tactattatg tctggagggt
    17821 ttaatcctca aaagatagga ttttctataa gccaattaga taaaccaatt attgcatggg
    17881 agtttgattc tttgaaaaca gctattgaga ctatctatgc ctttgcaatt acaagtgaac
    17941 cttcttcttt aaataaatgc aagtactgtg gtaaaattta tattcctaca aattctaaat
    18001 ctcaatactg ttcaccttct tgtagaaatt gctcaaatgt aaagaaaagt agaagtagag
    18061 ccaaaaaaga taaataaaat taataaatat atcattgttt agattttagt aaataactac
    18121 tgaattaaaa gttgttatag aaaattatat atctaaatga tggtattttt ttgttgagaa
    18181 aattgaaaag tttaattgag atagtaattt tgagttgaca aaaaccactt ttaacactac
    18241 tattataagt ggttggtaaa ataatataca ctaatttaaa tatagcataa aaaacaaaaa
    18301 aagtcaatga aaaaaataaa aaaggagaat ttaaaaatga tatcacctat tattttgagt
    18361 tctataaatc agaatttaaa ggaaatagaa agaaatgaac tgcttgaaac taatatagaa
    18421 tctggagatt atggtctagc tctttctgaa tctgatgtaa aagatataat aaattcgaga
    18481 gataatactt taaaggggta tggaagaata gaattagata taaaagttac aaaacagtta
    18541 atagaaaata tatatacatc acaatataca aatgtggaca attatttaga ggctattaat
    18601 gatatgcaag aaatttttta ttatttaaaa aatgaaactg atgacaagat atgtgatgat
    18661 gagattatag aaatactggg tgaattttat gaaaaatttt caggcaatat ggacaatgta
    18721 agaggagaag cagacgaatt tgcaaagaaa tttaaatttg gagaagttta atatatgata
    18781 ggagagattt tgtatgttaa ataatttaag taatattaat ataaacgaaa ataatttaat
    18841 aaagaaccaa tattccatat ctctacttaa ggaatgtcta aattgtaaag tgatagatga
    18901 aagagaagta tataatatac aacaagaaat atctctaata cttatggatt tgattaaaaa
    18961 atatacaaat ggtcaaagca catcagtaaa aacagaagtt gccgaaaaac tgttgatttc
    19021 aatatggtat gctattgatg catatataaa taagcttgga gatatagaaa aaagagttgt
    19081 ggagttgact gctaagaatg ttaaaaaagt gtaccttgga ggcattgaaa tattagagga
    19141 agagttagtt aggctgaaag atttttataa actaatgatg agtagaaaat tggatactaa
    19201 ttcaatagca tataatgata ccttgatgga gttatcaagt ttctttaaaa gttatattgt
    19261 aaaatttgaa gctcaggacg ttccagtaag tatagattat ccattggcac tagatgatat
    19321 ggatgttaag ggtatttatt atgtgaagaa ttatattgag agtatagata tagaaaatag
    19381 attttgtaac ctatttaaga aaaaagatag agaaaaatta ttttatgact atggggtgat
    19441 ttataaaata gattgtgatg ttatacttgt aaatttattt gaacttatta taaataattg
    19501 tattttttct actattttag gaaatgaagt gattaattta gaaatttcaa aatatgagta
    19561 tgaattttta gaaaaacaat ttaaaaatat gtacaataat attactgaag ataaagttat
    19621 aggctctgaa gaaagtaata taattgaatt gattgaagta gatgatagtt ttaacactga
    19681 agtagatagt aatttggatt ataatgattt tgaagaaatt aacagagaaa ttagaataaa
    19741 taaaaaaata actttactac ttatggaagc aattgaagta ttaataaaaa gattaagcat
    19801 agaagatgaa gatgtaataa gatatattaa aaaatatgaa aagatattta ttgaatctgt
    19861 gctaagctca ataaaaagta acacttttaa aagtatggta actgtgagta aaaataaaaa
    19921 tgaacactta gaagactata ttgttgatga tgaaagtaaa ttggatgatg aatcgtttag
    19981 agagatattc aatgagatat tagatagtac atctataatt gaaaaaataa gaataataaa
    20041 ggaaaatatc aatgctaaaa aagactttat cgatattctt gaatctgaat gtttatttgg
    20101 agaagagtat ttaatgttgt ttgcatcatt aagtgaatta gaattggcaa tattgggtag
    20161 tgtagtattt tatgaagata ttagaatgag agaaattaat atattagaat ttatgttaaa
    20221 tgagaaaact gaaactactt tatggaagac agagtacatt aaatttatga agaggcaaag
    20281 tgaagataag atatactcca tagaagagca tatgaataaa attaattaac aaaaaattgt
    20341 gaataaatag aatgttagta tataatataa tctgtaaagc atatcaaaaa tacatatatt
    20401 tggaggaaaa ttatgaaaga gtatatcata aataatgttg aagaaataag agaagaatta
    20461 attgatttat ctaagaaaat atgggaaaat ccagaattag cctttgaaga aaagtatgca
    20521 agtagcattc aaaaagaata cctaaagtca aaaggattta aaattgaaga agtagaaaat
    20581 ttacctactg gatttatagc aagttttgga gagggtaaac ctgtgattgg catacttgga
    20641 gaatatgatg ctttaccaga gctatcacaa tgtgtgagtg cagaaagaaa gccattggta
    20701 gaaggaaaag ctggacatgg atgtgggcat aacctgttgg gtgtagcagg tgtaggagca
    20761 gttgtttcta taaaaaaatt aatagaagaa aataaattta atggaacaat aaaatatttt
    20821 ggttgtcctg ctgaagaaga aggtggagga aagacagtta tgtgtataaa tggctgtttt
    20881 gatgatgtag attgtgcatt tacatggcat ccttttgata taaatgcacc ttggagaggt
    20941 ggaagtctgg caaacttatc tgtaaaattt aaatttaaag ggataacagc ccatgcagct
    21001 caagctcctc ataatggtag aagcgcactt gatgctgttg aaattatgaa tgttggagct
    21061 aattatttga gagaacatgt tattgactct ataagaatgc actatgttat aactaatggt
    21121 ggtggaagac ctaatgtagt tcctggattt gctgaaagtt ggtactttat tagaggtaaa
    21181 aaagcaaggg atgcagaaca tgttcttgat agattaataa aagtagctca aggagcagca
    21241 atgatgacag aaactgaaat ggagtataag gttacagatg gaatatatga ctatatacca
    21301 aaccaatgtt tgactgattt agtttatgac aatatggttt ttgttggttg ccctaaaaat
    21361 actcctgaag aagaagaatt tgcaaaaaaa ttgtgtgata ctcttactag agaagaaaga
    21421 ttaggtgtag caacatcatt acaaaatgat aaatctattg tagaaagtta tatacacaag
    21481 gaaatagttg acggtgacaa agataaagga ctagctggtt ctactgatgt tggagatgta
    21541 agttatgtaa taccagtggc tcaatttgca atggcagctt ggcctgttgg aattgcaagt
    21601 catacatggc agtcatgttc atcagcaggt tcaaatatag gattttctgc tatgataaat
    21661 tcagctaaag tactggcttg tagtgcttat gatgtattta tgaatactaa aattattgat
    21721 gaagcaaaaa ttgaatttga taaatcatta gatggacaaa aatttaaacc attggtataa
    21781 ttttggtaat aaaatatttc tggggggaat agctatgaga gaaaaagttg aaaaagtgct
    21841 tgaggaaaag ataaaaccag tattacaaag agatggtgga gatgtagagc ttatagatgt
    21901 aaatgaaaat ggtgtggttt tagttagact acaaggggca tgtagtgggt gtccaggagc
    21961 gactatgaca atcaaagcta ttattgaaaa tgttttggtg agtgaagttc caggagtaac
    22021 tcaagtatta ggtgtttaat agttagcgtt tattaaatgt atgttataca taagtattta
    22081 ataaagaagt aaaaaaaata gtgaagcaat atatatgaaa aagtatgata aagataataa
    22141 aacattatag aaataatgaa atatttcata tgtatatgaa gaaataagaa aaaatagtga
    22201 agcaatatat atatgaaaaa gtatgataaa gataataaaa catttataga aataatggaa
    22261 tatttcatat atacatatga aaaaatagta aaacaatata tatatgaaaa agtgtgagaa
    22321 aataataaaa tactatagaa acaattaaat attctatata ggtattaaga aacatgaaag
    22381 aaataatgga gtattataga taaatatgta aaagtgtgaa agaaggatgt agataaattt
    22441 gtcttataca aatttaccta cagtatttct tacacacttt ttattttact atccaaccat
    22501 accaataaac atacctataa agtatggaac taaccatata gtccatacaa ctatactaaa
    22561 cttatgaaag aattttttct tttcctcatc atctttgtat aggacaaaag tagcccaact
    22621 tgcatgaaaa agcataagca caattgcaag aagacctgta atactatgaa ggttttgtga
    22681 taaagcagat tttacttcaa aagtatggct gttggctatg ttactcattg taaatgttcc
    22741 taaagtatca aatataaacc caagccaaaa tataattaca tgtttctttt ttaaaatttt
    22801 tgcctttctt tctccaaata cacctatagt gtagaaaatt aaagctgatg ttataaatac
    22861 tattgcaagt attaatttat aattcataat tatctctcct ttacttttgc caatatattt
    22921 ctaagatttt ttactaagtc actcaattcg ttttcatcac aatttttaaa aatatcatca
    22981 aaactttctt gcattttaat tttaaaattt gtggcaaatt caaatcctgt tgttgtaaac
    23041 ttaacgtatg tatttctttt atcattagat ttcttgaatt tttctatata tccaatctgt
    23101 tctaatctgc tgattatgcc tgaaaccgta cctttagcta aagacatttc atcacatagt
    23161 tgtgatattg taagttcttg attatgagct accagtttta taactataat ctgttggtgt
    23221 gttaatccat tttctttaaa attttcttct actgtgtaca tagttttaga ataaagttct
    23281 tttaagagca tggctattct aaaacagtca taattacttt tcaataaaat cacctcttaa
    23341 atggtttgca tacaaactaa tataatatac ttttcttata tagtcaacct aaaattttat
    23401 aattttatag aaaataatga agaatagaac ataaaaattt tattttaggt ataaataaaa
    23461 taatttgatg aaattttaac aatttttaaa aagtttgttt acacagttaa taaatgatgc
    23521 taaaattaac tcatagataa atatagaaaa tttaattttg tttaatgata atggaaccac
    23581 gaaggtttta acgttacttt acgtttgctt ttatgtggtt tttttattgc aacaaagggg
    23641 ggttggggtt tgttaaagga tatactgaaa aagttgttgc agtttatttt agtaatgttt
    23701 ttattatctt ttattgtttt ttacatggca agacttgctc caggagaccc attaatctct
    23761 tactatgggg atggagtaga aagaatgagt acacaagaaa aagaaaatgc tatgaaaaaa
    23821 cttggtttga atgaaccaat atacagtcaa tatataaaat ggatttcaaa tgcatcaaaa
    23881 ggggaatttg gaatttcatt taaatataaa caaaatgtta cttctgttat aaatgatgtc
    23941 tatataaaca ctataatatt aggtggttca gggtatatac ttacctttgt gctagcctta
    24001 ttgttaggaa tattttgtac attacatgaa gataagctca ttgatagaat catatgcaaa
    24061 ttaggaacaa taaccaactg tattccatca ttttgggttg ccttagtact catacttata
    24121 tttagtataa acttaagtat acttccaagt agtggtgctt attcaatggg agaagagtcc
    24181 agtatattaa gtaggatatc acatctaatc ttacctctta cagtacttat attaagccat
    24241 ctatggtatt acacatatat gataagaaat aaattactag aggaaataag agaagattat
    24301 gtgcttttat gtaaagcaaa aggtttaaat aatagaacta ttgtttttaa gcattgcctg
    24361 agaaatataa tgccatcata tattagtata atggccattt cgatacctca tatactagga
    24421 ggaacttatg tagttgaaaa agttttttct tatcctgggt taggaacact ttgttttgaa
    24481 agtgcaaagt atcatgatta taatatgtta ttagttttat gcttaataac aggggcttta
    24541 gtagtatttg ggaatatgtt agctcaaatt ataaacaata aaatagaccc tagaatgaaa
    24601 tatgatagag gtgatactaa tgaagccaca atatagtgat tttgaaattg taggagaaaa
    24661 ttatatttta gtagcagaag atgaacatat agaaacaaag aaaaccttat ctaaaaaaat
    24721 taaagaatta ccatatatat caattattat tttatcaatc atagtcattg gaagtgtatt
    24781 ctcatctttt ataatgacac atgaaccaac atacatggat ttagcaagtt ctaatttagc
    24841 tccaaataaa acttttttat ttggaacaga ctcaatgggt agagatatat attctatgat
    24901 atggtatgga ggaaaaatat ctttatttat aggactattt tccactgtaa tatcaactgt
    24961 tataggaatt gtttatggta gtataagtgg ttcagcatct gaactcgtag atgatgcaat
    25021 gatgaggttt acagaaatca tacttagtat accttcaata ttaattataa tatttgtaca
    25081 agctatactt ggaaattcaa atccagtatc tatgtccata gtaataggga taacaagttg
    25141 gatgaatata tctaagatag tgagaacaga agttagacaa ataagaaata gcgaatacat
    25201 actagcagct aagagcatgg gaggaggatt cttctatgta ttaaagcaac atttacttcc
    25261 aaattttgtg gcatcaataa tgttcatggt tgtaacaaac ataggcgcag ctattggtac
    25321 tgaatcgaca cttagctttt taggaattgg tttaccaata gaaattgttt cttggggaag
    25381 tatgttatct ttgtcagagg aagcattact ttcaaataga tggtggatta tactgattcc
    25441 gggtatattt ttggttacca cattggtgtg tataacaaat ataggtaatt atataagaaa
    25501 gaataataat aaaaaatcta gtaatttata aatcagcatt tgagtactaa ataagcaaat
    25561 actgaggtat ttgaaatatc tatttaaata aatggggtca aagctttgaa aaatatttta
    25621 taaaaagcaa aagggggagc atcatgaaat taaagaagtt aaaagtttta agtttagtaa
    25681 tgatacttag tctaatggca ggttgttcta gtggaggaga caaagataag aaggcagata
    25741 cgcctaaaga tggaaaggta cttgtttatg gaagtaatga ctatacaagt ataaatcctg
    25801 cactatatga acatggagaa ataaattcat taatatttaa tggattaaca gctcatgatg
    25861 aaaataataa ggtggttcct tgtctagcaa aggactggaa atttgatgag gcaacaaata
    25921 catatacttt taatttaaga gatgatgtta agtggcatga tggagagaaa tttacggcaa
    25981 atgatgttaa gtttacaata gaaactataa tgaatccaga taatgcttct gagatagcat
    26041 caaattatga agatataaca aaaattgatg tggttaatga taatactata aaaattactt
    26101 taaaagctcc aaatacagca atgcttgatt atttaacagt aggagtatta ccaaaacatg
    26161 ttttggaagg taaggatata gctactgatg aatttaatca aaaaccaata ggtactggac
    26221 catttaaact tgaaaaatgg gacaaaggtc aaagtataac acttgttaag aatagtgatt
    26281 attttgtaaa agaaccagga ttagataaag tagtctttaa gattgttcca gatgataagg
    26341 ctaaggcaat gcaattaaaa tcaggagaat tagacttagc tcaaataact cctaaagata
    26401 tgtctaactt tgaaaaagac gaaaagaatt ttaaagtaaa tataatgaaa acagccgact
    26461 atagaggtat attatacaat tttaattcta aattctttaa agataaaaaa gctaaaggat
    26521 taccaaatgc tttaagctat gcaatagata gaaaagcaat agttgacagt gtattattag
    26581 gacatggtgt accagcatat tcacctttac aaatgggacc atataataat cctgatatag
    26641 aaaagtttga atataatcca gaaaaagcta aacaagaaat tgaaaagcta ggttggaaat
    26701 taggttctga tggaatctat gaaaaagaag gtactaagtt agctttcgag ataacagcag
    26761 gtgagagtga ccaagttaga gttgatatgg ctaaaatatg tgcacaacag ttaaaagaaa
    26821 ttggtgttga tgctaaagct gttgttgtaa ctgaaacaga ttgggctaat caagatgctc
    26881 atttaatagg ttggggaagt ccatttgacc cagatgacca tacatataaa gtatttggaa
    26941 cagataaagg tgcaaattac agtgcttact ctaatcctac tatagataaa atacttcaaa
    27001 aagcaagaga aacagaagat aaagatgaaa aattaaagtt atataaacaa ttccaagtag
    27061 aaatgactaa ggatatgcct tatacattta ttgcttatat agatgcaata tatgttggaa
    27121 aaccaaacat aaaaggatta acacctgata cagttttagg tcatcatggt gtaggtatat
    27181 tctggaacat agctgactgg acaattgaat aatactgaaa ttaattagaa accttaggga
    27241 taaaaatata tccctaaggt ttgaatagca taggggttga tggtttttgg aacatttatt
    27301 ggaggttaat aatctatctg taagttttaa agtagaagaa ggagaagttc aggctgtaag
    27361 aaatgtatct tttaatctaa aaaaaggtga gacattggct atagttggag aatctggttg
    27421 tgggaaatct gtactgtgta agagtttgat gaggatactc ccatacaatg gatatattaa
    27481 aaatggagag gttttactta aatcaagtga tttggttaag aagtctgaaa aagagatgga
    27541 agatataaga ggaaagaata tatcaatgat atttcaagac cctatgacat ctctcaatcc
    27601 aactatatca ataggaaagc aaattgcaga agctgtaatc attcatcaag gtataagtaa
    27661 aagtgaagca aaaaagagag ccatagagct tattgaattg gttggaattg ataatcctga
    27721 gaaaagattt aaacaatttc cacatcattt ttcaggtgga atgagacaac gtatagtaat
    27781 agctatagca cttgcctgta atccagatgt attgattgct gatgaaccta caactgcttt
    27841 agatgtaact atacaagctc aaataattga tttaataaag gatttacaac ataaaatagg
    27901 tttgtcaata atatttataa ctcatgattt aggagtagtt gcaactatag ctgatagaat
    27961 agcagttatg tatgcaggaa agattgtaga aataggaact gtagaggata tattttatga
    28021 ccctagacat ccatatactt gggggttgtt gggttcatta cctactttag attcacagga
    28081 tgaatattta tataatatac ctggaatgcc tccaaattta ttgaacccac caaaaggaga
    28141 tgcttttgca ataagaaata aaaatgcact taagatagat tatgaaaaag agccaccaat
    28201 gtttaaaatt aatgatacac atagtgcagc aacttggtta ttgcacccag atgcacctga
    28261 agtagatgta ccagttagag taaattgtgg aagggtgatt tctaatgaat agagaaaaaa
    28321 tactggaaat aaaaaactta aagcaatatt ttcatttgga caaaagtact actgtaaaag
    28381 cagttgatga tataagtttt gatatatata agggtgagat atttggattg gtaggagagt
    28441 cgggttcagg aaaatctaca actggtaaaa ctataataag actacatgaa tctactggtg
    28501 gagaagtaat ttacaaagga aattgcatat cagataaaaa aacgtacaaa tttataaaaa
    28561 aagatgtaaa caaaagtatg cagattattt ttcaagattc tacttcatca ttaaatccac
    28621 gtatgacaat tgcagatata atttcagagc cactaaaaat tcaaggtatc tgtaaaaata
    28681 aaacagatag aatgaataaa gtatatgaga tgctaaagct agtaggactt gatagaagtt
    28741 atgcaaataa gtatccatct gatttttcag gtggacaaag acagcgtatt ggcatagcac
    28801 gagctctttc agtagaccca gaatttataa tagctgatga gcctatagct tctttggatg
    28861 tgtctataca agcacaaata gtaaatttat ttaaaaaatt gcaacaagaa aagaatttaa
    28921 cttgtttatt tatagctcat gatttatcta tggtgagaca tattagtgac cgtataggag
    28981 ttatgtataa tggaaaatta gtagaattgg cagattcaaa tgaattgtat aataatccta
    29041 ttcatccata tacaaaatca ctactttctg caattcctgt tcctgaccct agatatgcta
    29101 agtcaagaaa tagaatagag tataattcta atggatatga ttgttcaaat gaaaagtcat
    29161 taagttggat tgaggtttca gatggacatt ttgtatattc ttctaaatca gaaataaata
    29221 aatatcaaca aaatttaaaa gttgtttagt ataaaaatac ttgaacaggt atttatttga
    29281 aatacaaact aaaaccctat ttttggagaa attttaaaac tactccaaaa tagggttttt
    29341 tatttctact tttcaaatat aataaattca aatataataa aattaaaaac aagtaaagta
    29401 tgttgttaag aaagtgctat aaaattaaaa atagtaatgt agaaaaaatg agcaataatc
    29461 ttattttttc tacaataatt ttctataatt taaagtaagg aaagtttgat aaattataac
    29521 cttagttaaa gaataagagt ttattaaaaa ataaagtgtg tataggggtt ttagttaata
    29581 aaatattata atgtagggga gcttgtaatg atatataaaa aagataaagt aatgaaagtt
    29641 ttagaatcat catataggga aaatgaaaaa gggattacag ctaaccaatt atcagaaaag
    29701 acaggaattg caagaaacaa tataagtaca tatttaaacc aattattcaa tgagggtatg
    29761 gttacgaaga taaaaggaag acctgtgtat tatatccctg caaatcttaa ccttaacaag
    29821 aatgaattgc ttgatacaca aagtgagttg cttggcataa aaaaaggaac aaaagtagaa
    29881 aacaaaataa aaaaagatag ttttgaaaca ctaataggta aagaacatag tttaagacct
    29941 ataatagaaa aatgcaaggt cgcaatgctc tatcctacaa atggacttca tactattatc
    30001 tatggagaaa caggagtagg aaagagtatg attgctagat atatgtacga ttattctata
    30061 gatagtggaa ttagaaaaaa taaagctcct tttgtaacat ttaattgtgc tgattatgct
    30121 aataatgcac aattacttat gggacatatt tttggagtag aacaaggagc ttatacaggt
    30181 gcagaatctt ccagaaaagg tcttttggaa attgcaaatg gagggatact atttttagat
    30241 gaaattcata gactaccagc agaaggtcaa gaaatgttgt ttacttttat agataaggga
    30301 acatttaaaa gactaggaga tgcaacgaaa gaaagagatt ctaaggtatt aataatatgt
    30361 gctactacag aaaatccgac atcaacacta ttagatacat tcaatagaag aataccaatg
    30421 aaaatagaaa taccatcact gagagatagg acaatgattg aaagaatgga attagtcaaa
    30481 aattttttca aggaagaatc aaaaagtatt tctatttcaa taaaagtaca taaagaaata
    30541 attaaatcac tattacttta tgattgtaaa aataatgtag gtcaacttca aaatgatata
    30601 aaattagctg ttgcaaatgg atacctaaga tataaaagag ataataaaga accagtttat
    30661 atagagaaaa aatattttga taaatctata aatgaagtga gtgatgatta tagagagaag
    30721 tctattaaag cagatgaagt tataacacat ggaatagaat attttgtatt tacgtcatta
    30781 ggagaagaag aagttattaa ctacaatgat ataaatatta ttaatgcagt aaatactaat
    30841 cttaataaat ctgtagaaat gaatatagca gatgcttctc tatttaataa tgttaagttt
    30901 aaaagcatgt gtgaatcaat aagacaaatt attaaagaag atgaagaaat agatataagt
    30961 gaatcaatat ttaagtcaat ggcaatttat ataaaaagcg tattggataa aagtagctct
    31021 acaaacaaca tagatttgaa tcaaattaga agaaataaca gaagtgaatt taaaacagca
    31081 ctaaaaatag ttggaataat tgaaaatgaa tttgatttat ttttatctat agaaactgta
    31141 gcatatatta cattattcat agtacaagct aaacaagatg aacaaaataa aatagtgaat
    31201 aacattaata ttatagttgc tatgcatgga gaaactacag caagtaatgg taaaagcagt
    31261 tggtgatatt attggaaagt gcagtgctat ttctttcgat atgaagttag ataaaagcta
    31321 tgatgaagtt attgtagatt ttaaaaattt aattaataat atagacaata aagatgtatt
    31381 actatttaca gatatgggtt cattaaactc ctttgatgaa attataaaga aagaaaaaaa
    31441 gtgtgaagta agagtaattc ctatggtgac gacattaact gtgttagaag cagttcagaa
    31501 ggccaatatg ggattacctt taaatgacgt atacaactct atcactaaca cgagaaagta
    31561 ttattttgga actaatgaaa ttcaaaataa agaaaatctg tctaaaacaa ttattatagc
    31621 atcacatgtt tcagaaggtg tagataataa aacaagaaaa atattagaag aaaagatgag
    31681 taggtactta gatggaatag atattatatc tgtcccatat aaaacagaaa aagatttaag
    31741 tttaaatatt acaaaactta aagaaagtag taatattgtt gcagtaatca atgaacaaag
    31801 aattaatatt agaggaattg actatattag caaaaaagat atagataagg atgaaaatat
    31861 caataaatta aaaaatatta taaagataag tataggttat gatgatgtag ttgaaggttt
    31921 aaagacatcc ttaaaaagct ctaattataa taggatattt aaagatataa aatatgtgtc
    31981 tgatgaattg tttttagtat ttaatataga aaagaaatac gataaagtaa ttggacttat
    32041 gatgcattta gctttcatgg tagatgggtt gattggaaat actagagaaa ttgaaaagct
    32101 tgataaagaa aaaacacttg attatcacaa gagcctaagc aaaataaaag atatagtatc
    32161 tcaattagat aaaaaatata atatagaaat taatgaaaaa gagtgctatc aaatattatt
    32221 aatattagaa tatgcagaaa taatcgaaaa agattaccaa tgagtataaa aacttatttg
    32281 gtaatttttt ttagtctaaa ataatattaa tattagacac atataaatat acttagacaa
    32341 agtatctaag ttttgatgat aaaaatgatt gaaataacag tgttttaaag tgtctaaaaa
    32401 aactggcata atacttgctt atattattaa atgagtaata taaataatta aaatttaaat
    32461 aaaaaggagt aaataatatg caagataaaa tattaagaga taaaaaggca aatgacccat
    32521 gggcaagaat gactacaaga aacggattta gtgcagacga aataatatcg tcatttcaaa
    32581 aagctataag aagaaatatg gtggaagaag cttgtgaatt tgcttatgaa ctatatatat
    32641 catcaccaga attagaagat aagctatgga gaaggatact tacaatatca gttgaagata
    32701 taggaatggg ggacccatca gctgtaataa tcataaataa tttaaatcaa gtaagaaagg
    32761 aatattcata tgcagatgga gacagacctt tatttttcat acatgcaata agatatcttt
    32821 gtgcatgtga gaaagataga tcaagtgatt tattaaaaaa tataattata aaaggatttg
    32881 caatgggtaa agttccagaa gttatggacg tggcacttga caagcataca tatagaggat
    32941 tagaaatggg aagggattca ttccactttt taaatgaagc tagtatagta ataccagaaa
    33001 aagaagtaga taatgattat aaagaaagat acttaaaaat attagaaaaa tataagcaag
    33061 aagaagttat agatacggct ttcaagttta atcattggca gtactaagaa ttagagtaaa
    33121 tattaataag aattaaaata aaataataag aattaaagta aaaactgata ggaattagag
    33181 taagaattgg ctgataaaaa attagaaaat aaaagaggtt agatattgta ggagggtaat
    33241 tatgaatatt ttattagtat gtgcaaatgg agcttcaaca ggtgtacttg tggaaaagat
    33301 gaaaagtttt tgtagtgagc atgaaaagtt aaaaactaaa actataaata tagaggcaac
    33361 atcattcgaa aatttaaaat catacattga agctaatgat acagatgtag tacttgtagc
    33421 accacaaatt aggttcaagg aagatgatgt agttgaagct tgtaagaatt acaaaatagc
    33481 agttggttta atagatacta agcattatgg tcgtatggat gctccttctg ttatgaagtc
    33541 ggcaatcgaa ttatataaaa atagataatt ggggggaata aaaatggaag cacttcaaaa
    33601 taatttaaga agatttcttc taccaatagc acaaaagatt gaaaaacaaa ggcatcttca
    33661 agctataaaa gaaggtatga taagcattac cccaataata attgttggtt ctttaagtat
    33721 gttatttatg gcattaaaca atatgttacc tgaaggaagt gcaaaaacat tattatctga
    33781 aaatatggat acattactta tccctaataa atttactatg agtttattat ctatatattc
    33841 agcatttttt atagctcagg cactagctaa aaaatataat cttaatcatg tagaaatagg
    33901 tatgacagca gttgttgcac aacttgttgt atgtggacaa gtagtagatg gtgtattaga
    33961 tacaagttat ttagatgcac aaggtttatt tgtaagtata ttagtagcac ttttagtagt
    34021 tgatattact aagtttatga atgataaaaa tctcgtaatt agatttccaa aagaagtacc
    34081 tagtgtagta aataaaagtt ttagaaattt aactccaatg atagtatgta taatgttatt
    34141 tacagcaata gcagcaataa ctaaaaatgt ctcaggtcaa ccattaccag ctattataat
    34201 gaatttctta gcaccagcta taagcagtgt agataatgtt tttgcagtaa ctataatact
    34261 atttataact caattattat ggttctttgg ccttcatgga gcagcaataa cttcaagtat
    34321 atggatgcca atagcagcta catatatggc agaaaatgca acactgatag cagcaggagg
    34381 agacccaaaa tatgtgttta caataggatt ttactatggt ttcttgcaag taactggttc
    34441 agggataact ttgggattag tgtaccttat gtcaagaagt aagtgtaaga gttttaatag
    34501 tatgggaaaa gttgtgattt taccatcact atttggaata aatgagccag taatatttgg
    34561 aacaccaata gttatgaacc catatatgtt tgtaccattt gtatttggac ctgtattggt
    34621 tggagcactt aattttatgg cattaaaagt aggattagta ggattaccta ttgcagaacc
    34681 accaggcttt ttacctccag gggttgcagc atttttgatg acattagatt ggaaggcaat
    34741 cgtattagta tttgcaagta taatacttat gaccttgata tattatccat tctttaagat
    34801 aatggagaag gaagaattaa ataaaaatgc agaattagct acaacattag atgatgatag
    34861 ctttgatttt taacaagtca ttagaaggag aaggatatgg tacctgaaat ggaagaaaaa
    34921 gtatttagta taatatcaga agcaggagat gctaaaagtg atgtaatgat gtctcttaag
    34981 gaaataaaaa aaggtgacta caataaagca aaacaccttt taaattcagc ctcagagaaa
    35041 atacaaacag catcaaagca tcatttagaa ttactatcaa atgctatgaa tagtgaagat
    35101 agtgggactg attttttagt tgtgcactct gaagaccatt attcaaatgc attatttgct
    35161 cattctttag tatctgaact tgtagatata tttgagatga tggacccaag aattaataag
    35221 aattaaattt cttgtaaata gtgcttgaag tttggctata gtttattaaa tcaatagatt
    35281 taataaatga actccctttt actttaaagt actagtattt ataaatttat ttataaatac
    35341 agtaaatttt taaatagaaa aggagatatt attatggaaa aattttcagt agtaatagct
    35401 ggaggaggaa gtacatatac cccagaaatc atattaatgt tgctagataa cttagatagg
    35461 ttaccattaa gagcaatcaa attatatgat aatgatgaag aaagacaaaa taaggtagct
    35521 aaagcttgtg aaatactaat aaaggaaaag gaccctaata tagagtattt agcaacaaca
    35581 tgccctaaag aggcttatac agatgtagat ttttgtttag ctcatataag agttggaaaa
    35641 cttgaaatga gagaactaga tgaaaagata cctctaaaac atggagtagt tggtcaagaa
    35701 acttgtggac caggtggaat agcttatgga atgaggtcta tagaaggtgt tcttgaaaac
    35761 atagattata tggaaaagta ttctccaaat tgttggatgt taaattattc taatccagca
    35821 tcaataatag cggaagctgt tagaaggttg agacctaatt ctagggtaat aaatatttgt
    35881 gatatgccaa taggtatgga acataatata gcaaggattg caggactcaa atctcgtaaa
    35941 catatggata taagatactt tggattaaat cactttggtt ggtatacttc aattaaagat
    36001 aaaaaaggaa atgaactttt accaaaatta gtagaacata taaaagaata tggttttata
    36061 aatggtgaag aaggaatgaa aaatgacaag aaagatagtt ggtttgaaac taatttattt
    36121 actaaagaaa tagtaaaaac agatttaact acaataccaa gtagttactt aaagtactat
    36181 ctatttccag attatgttgt aaatcattct gatgtaaatt atactcgtgc caatgaagtt
    36241 attgatggaa gagaaaaaga agtttttggt tcatgtgcat tgatagaaaa gcaaggacat
    36301 tctaagggca gtgggcttaa gataggaata catgcagagt ttatagtgga tttagctaca
    36361 gctctagctt ttaatacaca ggagcgtatg ttattgatag ttcaaaataa tggagctata
    36421 gaaaatatac aagatgatgc tatggttgaa attccatgta tagttggaaa agacgggtat
    36481 gaaccattat caatagggaa aataccaaca ttccaaaaag gtttaataga acaacaatta
    36541 gcagttgaaa aattagtagt tgatgcttgg attgagaagt cttataataa attgtggcaa
    36601 gcacttatgc tatctaagac agttcctagt gcaacagttg caaaagaatt actagatgat
    36661 ttaatagaag caaataaaaa ttattggcca aaacttaatt aagaataata tatttttaaa
    36721 gttcctacag tttagtacat agcctagtta atgtatttgt agggacttta tttatttaca
    36781 aatgagatac aagtggcaaa catagtgtat tttgcagtta ggaaagtagg tttagttact
    36841 tgttagttgg attaaattta ggtacaataa tttactatca atcaatagaa ataaccagag
    36901 aagttgcata ataaaaaatt tacactttta acaggattta tgtaggtgtt tatagaaata
    36961 aataaatatg tacataaata cataattatt tttaagtcta aaatacaaga atggagagat
    37021 ggctatgaag tggagagatt atgctgatga tgtaaattta tttgaggatt ttgataaaac
    37081 tatcaagcct ctaactgacg aacaaagaag aaaaaatata aacactttaa ttgcatattt
    37141 ttcaaaagaa gttccttcta aaatatacaa tttatcaaat gatgaaatta agcctagaga
    37201 tatacttaga ggacttttga atgtatatcc accaaaagaa attgctccag agatacttaa
    37261 tatgttacat aatttattgt tgattgaatg tgaagaaaga gagttagtag atgtaaatga
    37321 tatagaagaa gtagaggaag ggattgccat atggagaggt aatataacga atttaagagc
    37381 agatgcaata gtaaatgctg caaataacaa gttattaggg tgtttacaac cattacatct
    37441 atgcgtggat aatgagatac attcatgcgc aggtcctaga cttagagaag attgtgacaa
    37501 aataataaaa aaacaagggc atttagaata tactggagat gctaagataa ctagaggcta
    37561 ttgtttacct gcaaaatttg tagtacatac tgttggacct attgtatctg gtggtcagcc
    37621 aagtaaagag caagaaaagc aactgcttca ttgttataaa tcatgtttaa atacaataaa
    37681 agaaattgat gaaataaaaa atattgtttt ttgtggaatt tctacaggtg tatttggtta
    37741 tccaaaaaaa gaggcagcta atcttgctgt aagtagagtt agactatggc taaaagaaaa
    37801 tcctgaaaaa aatttaaaag ttgtatttaa tgtgtttact gaagaagaag aagagaaata
    37861 tagaagaata tttaaataat attatgtaac agaatcctaa aaatacttat tatataa
//
LOCUS       DAMJWO010000039        37208 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.040, whole genome shotgun sequence.
ACCESSION   DAMJWO010000039 DAMJWO010000000
VERSION     DAMJWO010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37208
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.040"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(150..344)
                     /locus_tag="PC366_001951"
     CDS             complement(150..344)
                     /locus_tag="PC366_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577479.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSI
                     NIWADRVRANSYSYENKIAK"
     gene            complement(653..2182)
                     /gene="lysS"
                     /locus_tag="PC366_001952"
     CDS             complement(653..2182)
                     /gene="lysS"
                     /locus_tag="PC366_001952"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDF2577480.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            complement(2197..2676)
                     /gene="greA"
                     /locus_tag="PC366_001953"
     CDS             complement(2197..2676)
                     /gene="greA"
                     /locus_tag="PC366_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HDF2577481.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            complement(2785..3753)
                     /gene="dusB"
                     /locus_tag="PC366_001954"
     CDS             complement(2785..3753)
                     /gene="dusB"
                     /locus_tag="PC366_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HDF2577482.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRAAEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            complement(3890..4660)
                     /locus_tag="PC366_001955"
     CDS             complement(3890..4660)
                     /locus_tag="PC366_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HDF2577483.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            complement(4679..5269)
                     /locus_tag="PC366_001956"
     CDS             complement(4679..5269)
                     /locus_tag="PC366_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2577484.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTVTSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            complement(5453..6421)
                     /locus_tag="PC366_001957"
     CDS             complement(5453..6421)
                     /locus_tag="PC366_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HDF2577485.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLIVSALIAVNALGDVYENGKVIAGALNDKKTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKSIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKKREI"
     gene            complement(6414..7391)
                     /locus_tag="PC366_001958"
     CDS             complement(6414..7391)
                     /locus_tag="PC366_001958"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HDF2577486.1"
                     /translation="MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNIYYKLDTEFIGKNIEHLDTIDSTNEHAKRIAIN
                     SVDGTVILSEHQDMGKGRLGRRWDSKTHEGIWMSIILKPDMEPFKAPFITLIAGASVT
                     KALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IADKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNRELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV"
     gene            complement(7705..9675)
                     /gene="ftsH"
                     /locus_tag="PC366_001959"
     CDS             complement(7705..9675)
                     /gene="ftsH"
                     /locus_tag="PC366_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDF2577487.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIVVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(9709..11097)
                     /gene="tilS"
                     /locus_tag="PC366_001960"
     CDS             complement(9709..11097)
                     /gene="tilS"
                     /locus_tag="PC366_001960"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HDF2577488.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVNEE
                     IEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDSEGIICVGDYKISENYKIDEN
                     TKEVLKINFNKL"
     gene            complement(11280..11708)
                     /locus_tag="PC366_001961"
     CDS             complement(11280..11708)
                     /locus_tag="PC366_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HDF2577489.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVI
                     YKEKEENIEITNTIKILKNQVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDT
                     RELDINIQEGEHIKLKIDYNIKVQDLFLGRNKIDIYIGTK"
     gene            complement(11725..12531)
                     /locus_tag="PC366_001962"
     CDS             complement(11725..12531)
                     /locus_tag="PC366_001962"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HDF2577490.1"
                     /translation="MNNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKI
                     LEVQNIINNTEIHGTYQYYVSDIPEKFSDIAREFLKKKIDKIQKVEIQKY"
     gene            complement(12733..13218)
                     /locus_tag="PC366_001963"
     CDS             complement(12733..13218)
                     /locus_tag="PC366_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HDF2577491.1"
                     /translation="MATLLALTFIFMPIKEVFAYEPTENIKKVNKQEKNIAKKEVINL
                     SDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQKNAFSVVL
                     DGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMRIGNHVFA
                     K"
     gene            complement(13269..13928)
                     /gene="spoIIR"
                     /locus_tag="PC366_001964"
     CDS             complement(13269..13928)
                     /gene="spoIIR"
                     /locus_tag="PC366_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HDF2577492.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEIKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILKNGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVLEVVKDLEKK
                     F"
     gene            complement(14073..14753)
                     /locus_tag="PC366_001965"
     CDS             complement(14073..14753)
                     /locus_tag="PC366_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2577493.1"
                     /translation="MENLTKLNLDNYKPLRDVVFENLREAILEGKLKPGQRLMEVQLA
                     EQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLEVRASLEGLAAYL
                     AAERISDEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKATNNKKLIQLINS
                     LWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYATEHIEKAEQFMID
                     KAMISKDL"
     gene            complement(14737..15627)
                     /locus_tag="PC366_001966"
     CDS             complement(14737..15627)
                     /locus_tag="PC366_001966"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HDF2577494.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNHLWELRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTNIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(15745..17295)
                     /locus_tag="PC366_001967"
     CDS             complement(15745..17295)
                     /locus_tag="PC366_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HDF2577495.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVVQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVEGIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(17389..17655)
                     /locus_tag="PC366_001968"
     CDS             complement(17389..17655)
                     /locus_tag="PC366_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HDF2577496.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(17803..18663)
                     /gene="yabG"
                     /locus_tag="PC366_001969"
     CDS             complement(17803..18663)
                     /gene="yabG"
                     /locus_tag="PC366_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HDF2577497.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(18747..19685)
                     /locus_tag="PC366_001970"
     CDS             complement(18747..19685)
                     /locus_tag="PC366_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HDF2577498.1"
                     /translation="MKFIDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMANKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLKKFYDLGVRMMTISWNHVNELSFPHNKVEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDDIEKIYYKNALRVIKEVL"
     gene            complement(19795..19956)
                     /locus_tag="PC366_001971"
     CDS             complement(19795..19956)
                     /locus_tag="PC366_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577499.1"
                     /translation="MFILRFADDDDNLSVKDFTSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(19966..20463)
                     /locus_tag="PC366_001972"
     CDS             complement(19966..20463)
                     /locus_tag="PC366_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HDF2577500.1"
                     /translation="MSLYTEWRNLSDNHESQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEEVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(20578..21288)
                     /locus_tag="PC366_001973"
     CDS             complement(20578..21288)
                     /locus_tag="PC366_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HDF2577501.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNDVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWAKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYDVDVNNLKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFDLEVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     NQEYAIKVLKELFNYDII"
     gene            complement(21464..21994)
                     /locus_tag="PC366_001974"
     CDS             complement(21464..21994)
                     /locus_tag="PC366_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577502.1"
                     /translation="MDIRALPIRITKEEAIEIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIITLKIHKTKSIFKNRRYSNDINELKILVNGSTGSGSIVQDFPTYEIVKNVDCN
                     IVQYSNKDERRVKAKANKMAMRLIHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(22011..22241)
                     /locus_tag="PC366_001975"
     CDS             complement(22011..22241)
                     /locus_tag="PC366_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577503.1"
                     /translation="MSKLVSKVKKDLEIKWLGVDGFLVLLYFLITGFIFYGILTRNDI
                     IVGKIIPYGVMAVVIVIFFDYIYRVLKMTRKK"
     gene            complement(22256..23650)
                     /locus_tag="PC366_001976"
     CDS             complement(22256..23650)
                     /locus_tag="PC366_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HDF2577504.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWKIDKELIGLIMVGV
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTI
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(23776..25029)
                     /locus_tag="PC366_001977"
     CDS             complement(23776..25029)
                     /locus_tag="PC366_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2577505.1"
                     /translation="MENKSNFKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALSLS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGVLGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGILLFFLVEEKKDSGASDEGLSIKSLLKVVTMPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKGLNNKIA"
     gene            complement(25080..26234)
                     /locus_tag="PC366_001978"
     CDS             complement(25080..26234)
                     /locus_tag="PC366_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2577506.1"
                     /translation="MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGINGLTRDQASRKLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIKKLK"
     gene            complement(26793..27362)
                     /locus_tag="PC366_001979"
     CDS             complement(26793..27362)
                     /locus_tag="PC366_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2577507.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFAKKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSI"
     gene            27565..27792
                     /locus_tag="PC366_001980"
     CDS             27565..27792
                     /locus_tag="PC366_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2577508.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
     gene            complement(28011..28754)
                     /locus_tag="PC366_001981"
     CDS             complement(28011..28754)
                     /locus_tag="PC366_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDF2577509.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEREYNNAASQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILNLMGFANNYGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYITDNGIIIYFGVDEIAPESFGIPKFELKFSD
                     FGNFINLRFYCISPDIYVQSRGRAKHFMG"
     gene            28922..29794
                     /locus_tag="PC366_001982"
     CDS             28922..29794
                     /locus_tag="PC366_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2577510.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            29794..30459
                     /locus_tag="PC366_001983"
     CDS             29794..30459
                     /locus_tag="PC366_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDF2577511.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKSHKDAKEAELNYNVLDFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEICHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            30480..31337
                     /locus_tag="PC366_001984"
     CDS             30480..31337
                     /locus_tag="PC366_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2577512.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICM
                     TYKGSYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(31493..34039)
                     /locus_tag="PC366_001985"
     CDS             complement(31493..34039)
                     /locus_tag="PC366_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2577513.1"
                     /translation="MNIFNKVALQGLKKNRTRTLVTIIGVVLSAAMITAVTTFGVSLM
                     NYMTNGAIIKYGDWHVQFLDVDSSFVQEQRVNDEVANTATFENIGYATLEGNRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSSKVATDGGVKFAVGDTISLDVGKR
                     MSENEKLGQSDPYTAGSEVFVPQDKKTYTVVGICRKPVFEESSAPGYTLITKEDKQVK
                     TDSLSLFVTLKNPHQIRSYTSSTKDHASIFNDNVLRFIGVSDNNLFNMFLYSVGGIVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGAIGIPIG
                     VAIGIVSIGLVISVIAKNFANILYVNVPLTLTLSIPAIIVAAVVSMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQRVYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVADLKQMSNQRSEVTDQDIIFSTQGMKDNEMLKLYDKLKTANGV
                     YEGLYQKLMTYSCVAKVSELTDDYLNYEGSHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPAEEYTGQNAKLIAVSMVTKDNNIIDIFNSSSMNVSLTPETNGKLEIPERQNVNIS
                     FVKVVPPDSPPGIRSSDVKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     AEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWFSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(34039..34725)
                     /locus_tag="PC366_001986"
     CDS             complement(34039..34725)
                     /locus_tag="PC366_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577514.1"
                     /translation="MAFLKIEDLCKVYGKNENKVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(34808..35797)
                     /locus_tag="PC366_001987"
     CDS             complement(34808..35797)
                     /locus_tag="PC366_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2577515.1"
                     /translation="MFRNREFRKFAILFLLITILTVALGFAISIMTGILSIVSATTFG
                     IAFFVFTKNRYKSIAQISEQINLVLHNANHLYIAESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIR
                     MDWLITSLLKLSRLDAGIVVFQKEQIDVNNLISSALHQLLIPMELHNITLHIDIPKGV
                     RILGDLNWLSEAIQNIFKNCMESVGDNGKIDIVCEDNFLFTQLTIHDNGAGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAQNHPQGGAIFVIRFPK"
     gene            complement(35784..36470)
                     /locus_tag="PC366_001988"
     CDS             complement(35784..36470)
                     /locus_tag="PC366_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2577516.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKEKQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(36970..>37208)
                     /locus_tag="PC366_001989"
     CDS             complement(36970..>37208)
                     /locus_tag="PC366_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577517.1"
                     /translation="IEEPRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKMRRTAIEF
                     STEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
BASE COUNT        11908 a         6884 c         4169 g        14247 t
ORIGIN      
        1 actatatcat cttaaaaata tttcgtcaat actttttttg ttttttattt taaaaaaggt
       61 tataactttt ggttttttta ataaatataa ttaaaactaa tagatataac ccttgatatt
      121 acaaacaata catgcatata taattttacc tattttgcaa ttttattttc ataagaatat
      181 gaattagctc tcactctatc tgcccaaata tttatactct taactttatt aacattagtt
      241 gtaccctcaa aaatatccat tgcatcctta caaaaatata tcataacatc aagaaccaaa
      301 aatccaacac aaaataaaca taaaaaatta attacttgaa acatcagaca ttcccccaat
      361 aattttttat atatagtatt ctcataaatt attcttttta ccttctcata aattattcta
      421 aatattttca taataaatta ctttcaatca tattttctaa atataaagtc tcaatcaaca
      481 aaaactaata tcaatttcta acgtttgttg gtaatttata aattaaatat ctaaaagaat
      541 ctttgaagca tataaaaagc attctacact gacattttaa acaaaattta gctatttatt
      601 gctaatttaa tagctaaact ttatttaaaa cttagtagaa tgctaatatt tcttagtttt
      661 cttcttcttt atttggattg ttatcaatag gtttcatagt cgggaataat aatacatctc
      721 ttatagatgg agagttagtt aataacataa ttactctatc tatacctatt cctagtcctc
      781 ctgtaggagg tagacctacc tctaatgctt ttaagaaatc ttcatccatt tcaaaagctt
      841 catcatcacc taattctctt tttctcaatt ggtctataaa tcttcctttt tggtcaatag
      901 ggtcattaag ttcagaaaat gcattagcta actcccactt attagcaaat gcctcaaatc
      961 tatcagttct tcttgggtct tcaacatttc tcttagataa tggagatact tcaactggat
     1021 gatgagttat aaatgttggt tggattaatt tatcttctcc aaattcttca aagaaagcat
     1081 ttattacttc tcctcttctc attccaggtt ttatctctat acctttttct ctagcaactt
     1141 ctagtgcctc ttcatctgta tttatagtag aaaaatctac accagaatat tctttaacac
     1201 aatcttccat actcattctt ttccaaggtg gtgtaaagtt tatttctgtt ccttgatagt
     1261 taactatcat acttcctgta gcaacttcag ccatatgtgc aataacattt tctgttattt
     1321 ccatcatatc agtatagtct gcatatgctt gatataattc tattgcagta tattcaggat
     1381 tatgttttaa atccatacct tcatttctaa acattcttcc catttcataa actttatcaa
     1441 atccaccaac aataagtctt tttaaataca attcatttgc tattcttaaa tacattggta
     1501 tatgtaaagt attatgatta gttataaatg gtctagcatt tgccccacct gctatagtat
     1561 ttaatattgg agtctcaact tctaaaaatc ctctatcatc taagtatgct cttaatgctt
     1621 ttaatgcttt tgttctaatt aaaaaagcat tttttacttc tggatttact attaagtcaa
     1681 catatctttg tctatatctt agttcttggt cttttaatcc atgatatttt tctggtaaaa
     1741 cttgtaaaga tttacatagt aatactacag atttagcctt tacagatatt tcaccttttt
     1801 tagttttaaa gatttctcct tcaattccaa ctatatctcc aatatcatat gttgaaaata
     1861 cactatattc ttcctctcct atagcatcta gtcttacata agattggatt cttccctctt
     1921 ggtcttgaat atctataaag ccagctttcc cttgtattct cttgctcatt atacgtcctg
     1981 ctatttttgt agttttacct tcaagagaat caaagttatc ttttatatcc atagaataat
     2041 gagttctatc atatctactt tctttaaaag gatctctacc tgactcttgt aattttttta
     2101 gtttatctct tcttacttga agtacttcac taaggtcttc ttgaatttgc gcttcttcat
     2161 tgctttgttg attatttttc atttttttcc tccaaattat cttcttattt ctaatatttc
     2221 aaacttagca actccatcag gaacttgcac ttccacaact tctttcgcag ctctacctaa
     2281 aagtgctttc cctacaggag attcgtttga tattttacca tcatatgggt ctgcttctgt
     2341 cgaaccaact atagtatatt caacctcttc atcaaattct aaatccttaa ctttaactat
     2401 tgatcctatt gtaacaacat taaggtctat tttgctttca tctatgataa cagcttttct
     2461 aaccatattt tctaatttta aaattctttc ttcaacttgt gcttgttcct ttttagcttc
     2521 atcatactca gcattttcag ataaatcacc aaaagatata gcaactttta ttctctctgc
     2581 aacttctttt ctctttacaa cctttaagtt ttctaattct tcttctaatt tatcatatcc
     2641 ctcttgtgtc aataaaaact ctttattttc ttccattata aatacaactc cttcacaaat
     2701 ttcttaggaa ttttcctaat tatattttaa aaattttata atcttttttt aatttatgcg
     2761 ctatattata agtcactatt atttttatgt caaggagtct tccatatagt actccaattt
     2821 cgacacaact tcttgatagt cttctatttt gttaatttca tcccttaatt ttgcagagtt
     2881 tctaagtcct tttaaatacc aagcgatgtg ttttctcatt tcccttacag ctacatactc
     2941 tccatgttct tctactgcaa gttttaaatg cttaatggca gtacttattt tttcgttaag
     3001 agttggctct ggcaaaatct cgcctgtatt catataatgg tttattcttt taaatatcca
     3061 agggttacct tgagcacccc tacctatcat tatagcatca caaccagttt tgtctaacat
     3121 atttattgaa tcttctattg taaatacatc accatttcct ataacaggta tactcaaatt
     3181 tttcttaatc tctgcaatta tatcccagtc tgctttgcct gtataaaact gttctctagt
     3241 tcttccatgt attgctaaag cgcttattcc acaatcctct gctatctttg ctatttcaac
     3301 agcatttaca ctattatcat cccagccttt tcgaatcttt aaagtcactg gcttttttga
     3361 gttcttcact actgccctca atacctcttc tgcaagctta ggatttttca taagtgctga
     3421 accatctcca tttttaacta cttttggagc tggacacccc atatttatat cgagaatctc
     3481 atttgaataa tcattcatta tctctgctgc tcttcccata aactctggtt ctgaaccgaa
     3541 tatctgaact gctacaggat gttcttcctc ttctatctta agcatttttt tagtattttc
     3601 atcatcatag caaagtgcct taccatttat catttctgta tataaaagcc cacatccctg
     3661 ttctttacaa attaatctaa atggaaggtc tgttacacct gccataggtg atagaaaaac
     3721 tttatttttc aattctaaat ttcctatttt cattgttttt ctcctatttt tgcctttatt
     3781 ttgtgattta actttaaatt cttatttcct cattataata taccacatat agctagaaat
     3841 ctatcataaa aagggaattg gatatataac ccaattccct gtatattaat tattcttggt
     3901 ttttttcata tattattctc aatccttcta gtgttaaaaa accatctaca taatctatac
     3961 ttttcgtctc tgaagcaatc agtttagcta atccacctgt agctataacc ttaacatcat
     4021 cacaattcaa ttctttcttc atcatactta ttattttgtc aactaaacca acatatccat
     4081 aaattattcc agattgcatg gctgatacag tactcttaca aatagtcata cctggcttag
     4141 ctaattctac tctaggtaat ttagacgcac tttgaaataa cgcctcacta gatattttta
     4201 ttcctggtgc tattgttcca cccaaatatt cacctttttc agagatagca caaaatgtag
     4261 ttgctgttcc aaaatcaaca agtatacttg gtgctccata cttttctatc cctgctacag
     4321 cattaactat tctatctgcc ccaacttgtt ttggattatc atattttata tttagacctg
     4381 tttttatgcc tggacctact attaatggct gttttttaca gtactttata caaaagtttt
     4441 caagagaatg catgacattt ggaactacag atgatattat aacatcatca atatcactta
     4501 tattcacatt atcataatca aataggttac ttatcaggat tccatattca tcagacgttt
     4561 tttccctatc tgttttaatt ctccagtaat taactaattt gtcaccttta tatataccta
     4621 aaaccatatt agtatttcca acatcaaata ctagaagcat atgtcattaa ccttctttct
     4681 attttttgct tttcttaagt acagtggcaa cagcagctac tactaaagcc cctactattg
     4741 cttctggcac cccatttgct gcggcaagag ccattattac ttttcctgct gaaccacttt
     4801 tacccattgc atgaagatac ttgtcagcat ataagacata tatcattcct aaaactccag
     4861 ctgtatttaa cagagaacct attgcccctg taattaaacc tgatatgtat accttatttg
     4921 tagccttaat tattaactga tatacataat aagctaatac acctatcata actcttggta
     4981 atattgaaac taatggattt ataaaaacaa aagatgttac tgttgggttt gttatagcat
     5041 ttaagagact tgatatccca aatataaatc ctattgctgc cccaactatt ggtccttcca
     5101 taatagctcc aataataact ggtatgtgca ttatagttgc ttttgtaggt ccaactggaa
     5161 taaatcccaa tggagtcata gatagcataa tagaaatagc tgatagtact cctattatag
     5221 tcatctttct tacatttact tttcttactg atgcacttgt gttcatcata aaaaatacac
     5281 ctccgttcca gctcattaag atgccggact acttaatttt ttaatttttt tcgttttttt
     5341 cttataacta tgagtcaagc taccattgta ggatgcccgc tctaacaaga ataattttat
     5401 caagatgagt tgccattgtc aacaatttga caagaaaaat atgctaattt catcatattt
     5461 ctcgtttttt tactatatct ttatatgcca ttatattttc tacactatcc gcttttttta
     5521 ctgcatttat tatacttttt tccacaacct ctacagccaa tgaacctact aatgttatat
     5581 ctgcttctat ttctcctgtt gatattgtga atattgtatc tccatcatga ggtgtatgga
     5641 taggaaaaat agacttagca tatccatcat gtcccatttg agatatcttt ttacatccag
     5701 ctttggttaa cttagcattt gttgcaatta tcccaattgt agtattatct acactaaatc
     5761 cacctttact ttcaccttgt ttcattaatt tatatgtatc aattgtttct gtctttttat
     5821 catttaaagc accagctata accttaccat tttcataaac atctccaaga gcatttacag
     5881 caattaatgc agatacaatt agaccattat ctaattttat agaatagcta cctattccgc
     5941 ctttcatagc atattcctga cctcttattt ttccaacagt ggctccacaa cctgctccat
     6001 aatttccttg atttaaaata tcagtatttg caacttcaca agctctataa cccatcttta
     6061 aatctggtct acatttaaag ctccctactc ctaaatcaaa taaaactgct cctacaacta
     6121 taggcacttt acctacacct acatcaaagc caattccttt ttcttctaag tatctactta
     6181 caccacaagt ggattcaaga ccatatgcag aacctccagc caaaactact gcatgaactt
     6241 tttgaaccat atttacaggg tctaataaat cggtttctct agtccctgga gcagaacccc
     6301 ttacatcaac accgcaagta gctccttctt cacatattac tactgtgcac ccagtaagac
     6361 catttctatc ctcaacctgc ccaaccttta agccttctat atccaaaata ttattataca
     6421 tatccttttt ctcctcttat agaaacttca cctgaaataa tttcttttat acttccatca
     6481 cttctttgaa ctaataaatt tccctcttca tttatgtcta aacatttcac tagttctcta
     6541 ttatctcctt ttaatacata tatattttta tctataattg cagaataatc tctacatatt
     6601 tttaaggttt tttctttgga attatttaca gtataatcta aatataattt ttcaaattca
     6661 gtcaatacat tcctaacaat atctactctg gataacatat acccttcttt atacaatgat
     6721 gtggctttgt cagctatttc ttgttcaaaa tccattattt taacatttat tccaattcca
     6781 agaacaacat aatttgttct ttcaatttca gcagataact ctgttaatat accacatatt
     6841 ttttttccat ttaaaataac atcatttggc cattttatta atgtatttgc tcctagattg
     6901 tttaaagctt tcgttacact tgctcctgct attaaagtta taaatggagc tttgaatggt
     6961 tccatatctg gttttaatat aatactcatc cagattcctt catgagtttt tgaatcccat
     7021 cttcttccca atcgtccttt ccccatatct tgatgttcac ttaaaatcac agtcccatct
     7081 acactattta tagctatcct tttagcatgt tcatttgttg aatctatagt gtcaagatgt
     7141 tcaatatttt ttccaataaa ctctgtatct aatttatagt aaatattctg tgggcttaat
     7201 aaatcagttg gattttccgc taatcgatac ccttttttat ttacagattc tatattatat
     7261 ccctcttctt ttaaggcttt catatgtttc catatagctg cacgtgacac ccctaattgt
     7321 tttgataatt cttctcctga aataaattca gatttattat ttaatataat ctctattatt
     7381 ttatctcgca tatttcacct ctaatatgac ataatttcat gacttatttt cttctaataa
     7441 ataattatac attattaata tacttttaat actattaatt ttaaatttcc tttttaatta
     7501 ttataatggt tgttttatat tttatattga tgatttatat aattttacat tttatttaaa
     7561 taattttaaa ataataaaaa actgaaagta tcaattaaat taatacatgc aaatataatt
     7621 tgcttattaa tttaatatta tactttcagt tttagtattt aatccacatc agataataat
     7681 cttaaaatga ccaaggtctt aaaactattt atctttatca gatttatctt ctaaattttt
     7741 atttatatca ataacattgt ttctttcttc ttcatctttt tctaatttta tagttaattg
     7801 ttcttcaact tctttagaag aattttcctc tgtaactgca ttttcaattt cattcagagg
     7861 taactcttta ttaaatgctt ttacaaattg ttctgcatct aaagtttcat atataagtaa
     7921 agcttgtgct acatactcta atctatccat attttcttgt aatatacttc ttgtcttatc
     7981 atatgcacca tcaactatac gctttgtttc ttggtctatc tcaaaagcaa cttcttcaga
     8041 gtaatttctc ttacttgaaa aactattacc taggaatact tcatcatcac tgtcaaatga
     8101 cattggacca agtttagaac tcattccata ctttgttacc atacttcttg cagtagctgt
     8161 aactctttct aagtcatttg aagcacctgt agatacatcc ttaagtacta gctcttctgc
     8221 tactctacca ccaagtaaaa ctacaatatt ttctttcatt tcattttttg tagcatagaa
     8281 cttatcttca acaggaagtt gcattgtaaa ccctccagct cttcctcttg gaactattgt
     8341 aacttgatga acaggactta cttcttcaag tacatgggca caaactgcat gccctccttc
     8401 atggtatgct gtaagtcttc tttctttctc acttattact ttcgattttt tagccacacc
     8461 tgctataacc tttgttatag cttcttctat agtttccatc ttaattttct tttctctttt
     8521 tctagctgtt aatattgcag cctcattcat taagttctct atatcagcag gagtaaatcc
     8581 tggtgttctt ctagccaaga catccatttt tacatcatca cttaatggtt tatttcttga
     8641 gtgaacttta aatatagcct ctctaccttt tacatctggt gtaccaacaa caacttgtct
     8701 gtcaaatctt cctggtctaa gtaaagctgg gtcaagtata tctggtctat ttgtagctgc
     8761 catgattatt ataccttgat ttaccccaaa tccatccatt tcaactagaa gttgattaag
     8821 agtttgctct ctttcatcat gacctccacc aagacctgca cctctttttc taccaactgc
     8881 atcaatttca tctatgaata tgatagctgg agcacttttc ttagcctgtt caaataaatc
     8941 tcttactctt gaagcaccaa ccccaacaaa catctcaacg aaatcagaac cacttatact
     9001 gaaaaaggga actcctgctt ctcctgcaac tgctcttgat agatatgttt taccagttcc
     9061 aggaggtcct accataagca ttccttttgg tattcttgca cccaattcaa tatatttctt
     9121 aggattcttt aagaaatcta ctacctcctg caaatcttct ttttcctcat ctagtccagc
     9181 tacatcttta aatgtaactc tagttttttc atcatcttta tgaaccttag cttttgattt
     9241 gccaaaactc ataacctttc cgcctccacc ttgagactga ttcataaaca cgaaccaaat
     9301 aatcaccatg aagaatatta acagtaatgt aggcaacatt tcgacaaacc aaggtgtaga
     9361 tggcttagct tcaccaccaa aagttagttt cccagcctta gcttggtcta acacctcatc
     9421 tgcaagttta tttcccatca cttctgttgg aacatatgac ttaaactttg tatttgtatc
     9481 ttttatagta ccttctacag aagtttgatt tacaaagtat aatcttgata tattctcatc
     9541 tgttaattct ctatatactt cagagaattt taaatctttt attttttctg taggcttacc
     9601 tgagaattga actataccta ctataattat aaaaacaagt agataaaaac ctgccccttt
     9661 tagcaactta ttcaatatag aagccctcct ttcatacatt gctttgccct ataatttgtt
     9721 aaaattaatt tttaatactt cttttgtgtt ttcatcaatt ttataatttt cactgatttt
     9781 ataatctcca acacatatta ttccttcact atctgtgatt ataggaattt tacatctttc
     9841 ttctcttggg atttttaaat ctatgaataa atctttcact tttttacttc ccatagcaag
     9901 ctttatctta tcaccttgcc ttctgcttct tattactata ccccctttta ccttattaaa
     9961 atcaaaccct ttagatgaat tgtctaattt catactctta tacctatcta tgctcattac
    10021 ttgggtctca ataatttgtt ttaattcttt tattttaata aacccattac taggtacatt
    10081 gtaataaaat tcaatttcct cattaacaat ttcctcattc gttaatatta tactgtcttt
    10141 ttttctataa acaaatatat ttcttggaag agttaacatt ttatttactt ttgaattatc
    10201 ttctaaagac attatatctt ctatatgtct ttggtcaaca aaattagtat ctcctagtat
    10261 atgttttatg gaatttctaa gaactctaac tttgatagca tcatgtaagc aaacaaaatc
    10321 gtctaaattt atctctacaa agcctttttc ttttatattt gaaacttctc taaatttagc
    10381 ttctgcctct ttctcaatat aatcgttatc actttttaaa ctattgctca tcctcactat
    10441 agattctatt acatttgaat taaaattatc cttcatatat ggtaaaaggt ctaaccttat
    10501 cttatttcta gtgtatatat tttctaaatt tgttttatct atcctcggat ttaaattata
    10561 agcttcacaa tactcctcta tctcatttct ttccacgtct aatatgggtc taattatgca
    10621 attatctcta atataatcaa ttccctttaa gccttttaag cctgttcctc tcatgatacg
    10681 catcataaca gtttcggctt ggtcattgag attatgacct attgctattt tattggcttt
    10741 aatcttatcc ttaatttcat aaaacatttc atatcttagc ttccttgctc cttcttctaa
    10801 tgataatccc tcattttcac aatattttgg tacattaata gactttacaa agaatataat
    10861 tcccatatcc tcacaaagtt tagatacata taatgcatct ttttgagctt ctatccctct
    10921 tatttgatgg tttaaatgtg ctgcatatat ttctatatta aaatcttttt ttaatctatt
    10981 tagtacatgc aataaacaaa ctgaatcagg tcctccagaa agacctaaaa ctattttatc
    11041 gcctttttgt attaaattat gtttatttat agtacttagt accttatcaa atatcatatt
    11101 tatccctctt acacttagtt ttattcactt ttaagtatac tttctataaa aaaacgctaa
    11161 acccttgtat caattttaag aaattaaagt ttaatataaa tataataata ccaaataaat
    11221 taaataaaag gtagtttttt cactaccttt ataaaatttc tggaaaatag ccatagttat
    11281 tatttagtac ctatgtatat atctatttta ttcctaccta aaaataaatc ttgtaccttt
    11341 atattatagt ctattttcaa ttttatgtgt tccccttctt gtatatttat atctaattct
    11401 cttgtatcaa tatcaattaa taaagtacct tgtggggtca catactttgt agtactactt
    11461 tctccacatt taaacagcat tgttgagtta atagcaccaa actttttgat actaacttga
    11521 tttttaagta tctttatagt attagttatt tctatatttt cttctttttc cttgtaaata
    11581 acatatattc catcattttt ataaaaaatt ttaccaaagg cagtcatctc tatggtgtcc
    11641 atatttcctt tttcatcata ttgtctagta tttatactta tttttacact caacgatttt
    11701 tcctccatag attcttcata taaactagta tttttgtatt tctacttttt gaatcttatc
    11761 aatttttttc tttaagaact ctcttgctat atctgaaaat ttttcaggta tatctgatac
    11821 ataatattga taagtcccat gaatttctgt attgtttata atattttgca cctctaaaat
    11881 cttttttaaa tcctttgcag tctctttagc tggattaaca agttttatat gctctccaac
    11941 ttcttcacct attgttctct ttaaaatagg ataatgagta catcctaaca ctaaagaatc
    12001 tatatttttt tctttcaatt cttgtaaata tatctttgct gtcaatttag ccacttctgt
    12061 atttgcccat ccttcttcaa caataggtac aaataaagga catgctttat taacaatttc
    12121 tatactctca tctattttag atatttccaa gttgtatgct tttgaactta tagttccttc
    12181 agttcctatt attcctacaa ttttgttttt tgtagaactt acagctgttc tagctcctgc
    12241 ttctataact ccaattatcg gtatatcata tttttcttga gcttctttta agcttcttgc
    12301 agtagcagtg ttacatgcta taactatagc ttttacacct tttgttttta aaaagtttat
    12361 agcttgaaaa gtatatttaa ttatagtttc tttggatctt gaaccatatg gtattctggc
    12421 agtatctcca aagtatatta tatcctcatt tggtaatatc ttcattatct cttttagaac
    12481 tgttaatcca cctaatcccg aatcaaaaac tcctattggt ttattgttca tctttataca
    12541 acacctactt tacatttttg tgtttaacaa caacttattt atcgctaaaa tttatattta
    12601 tattcataat taatatatta ttacctaaat gattattata gtttatttta cacaaaaaat
    12661 aaaggagcta tcttaaatta gaaaataatt tctacaaaaa gacaactcct ttcactactt
    12721 aaaaatttaa atttattttg caaacacatg atttcctatt ctcatataag gattcaatct
    12781 atttatccat ttgcaagtgg ctatttctgg attccaaaaa tatactgctt tattagttgg
    12841 gtcagttcca taaagagctt cctgagctgc tttacgtgct gagtctgttg gtgccatctt
    12901 tattgaacca tcaagcacaa ctgagaaagc atttttttga tatatgactt cttctattgt
    12961 gtctggaaat ctagggtcca atactctatt tattactaca gctgctacag caacctgtcc
    13021 ctcatagctt tctcctctag cttctcctgc aaccaactta gataataaca tcaagtcatt
    13081 atcagataaa tttattactt ctttctttgc tatatttttt tcttgtttgt ttactttctt
    13141 aatattttct gttggttcat atgcaaatac ctctttaata ggcataaata taaaagtcaa
    13201 agctaatagt gtagccatca gtttactcca cctgtccatg attaaaacca ctccttacat
    13261 tcttattttt aaaatttttt ctctaaatcc ttgactactt caagtacttt aaacttaatt
    13321 tttactctac ttgttttttt tggtgtatct tgttttatta acttatattc tttatcagtt
    13381 aaaacttcct tcaacttatc atctgtagat ttatctatca ctccattaga ttcatcaaca
    13441 aaacatagtg gagggaacat aacacaccac cagttttttc cttcaccttt cccaatgata
    13501 atctttaatg ctttatattc accagctgga agaactatat tagaatattg tttagtaggg
    13561 aaattgctat attgtatacc tacctttaca ctgtaattat atccattttt aagaataata
    13621 tttttactta tttcttccag actactatat tcctttttta taatagcttc actttctttt
    13681 atactttttg aattttgaag ctttggctgt aaatatttta ttacttcatc tctaactttt
    13741 agtttaagtt cttgatcttc atctgtattg ctgtttgcta taacatgaaa tcttattaat
    13801 ttatctttat aatcttttga tatattgtct acttttttta tctcaccatt tattactatt
    13861 gtcattattg atatgactga tataagactt aatattaata gtcccaatct aatcttaatt
    13921 tttctcattg aaaattcccc ctcaagataa atttatatca tcaattatgt ccaattaaat
    13981 ttaatttatt cataatattt tttaatacta ataaaaaaag ctatcttaaa atgattacaa
    14041 tcattttaaa atagcttttt aaaccttata ttttataagt ctttactaat catagcctta
    14101 tctatcataa actgctctgc tttttctata tgctctgtag catacttctt ggatagctca
    14161 ctatcacctt taattatagc atcaagtaag tatttatgct cttcaacaat attatgtgat
    14221 gtatcataag cagacatata ggtaactcta aatctatata cttgttccca taatgagttt
    14281 attagttgga ttaatttttt attattagtt gctttaaata tacattcatg aaattctaca
    14341 tcaagtttta ataacgcatc tacatcggat tccaaagtgc tttttttaaa ttcttctgat
    14401 atatctttaa gctttttaat atcttcatca ctaattcttt cagcggcaag atatgctgct
    14461 aagccttcta ggcttgctct tacttctaat acatccataa tatcctttaa tgacatattt
    14521 gccacatacg caccttttct aggcaacata acgactaaac cttctaattc aagctttctt
    14581 attgcctctc tcactggagt cctacttact cctaattgtt ctgctagttg cacttccatt
    14641 agcctttgac caggctttaa ttttccttct aagattgctt ctcttaaatt ctcaaagact
    14701 acatctctta atggcttgta attatccaag ttcagtttag ttaaattctc cacaaatttc
    14761 aacccctttt tgactgctat taacaacata cacctgttta tattttttta ataattcttt
    14821 ttttccaatt agagcatctt ctttattttt aaatagtcca aaaactgtag gaccacttcc
    14881 actcatcata gaacctaaag cattattttt catcattact tgttttatat cacttatttc
    14941 tttgtgttta cctatagtaa cattttcaag aatatttacc atgctttctg atacagcttt
    15001 tatatcttca gattttaaac actctatcaa atatttatta tttggtcttt ttttaatatt
    15061 attcaaatct aatccttgat aaacttcttt agtagaaacg aataagtctg gtttgcatat
    15121 caatatattt gtatcacatg gtaaaccttt gatgtttgtt agcttttctc caataccttg
    15181 agctaaggca ggtcttcctg atatacaaaa aggaacatct gcgcccaaat taagtcctat
    15241 ttcttttaat tcatcttcag ataatctaag ttcccatagg tgatttaaac ctactaatac
    15301 tgcggctgca ttagaacttc ctccagccat ccctgctgct acaggaatat ttttttctat
    15361 gaatatttct acaccttttt ttatataaaa tttattttta agtattttgg cagctttata
    15421 aacaatatta tcttcatcta aaggaatatc taaactagtg ctttttacct ttatttcatc
    15481 ttcgtctaat tcttttatct ttactatatc gtataaatct atcgtttgca ttatcatttc
    15541 aacaaaatga taaccgtctt gcctttttcc caagacatca atggataaat ttatttttgc
    15601 tctactcttt agtcttataa aatccattct atcctccttg tttaaagaat aatgcatcac
    15661 taacaataat attatactac aaaaaataaa ataatagggt attataatac cctattatac
    15721 ttaattactt taaatttttt aatattaatc tactaatacg actttttttt ctaaaataag
    15781 acacttacca ggcttaattg gttcatcaag ttttatatca ttaagttctg caatttcatt
    15841 ttctgttgta ttgtattttt ttgctatatt ccagaaagta tctccttctt tgcatatata
    15901 tacgattatg ctaggagctt tagataaatc atatacacct tggtcttctc ctttgataat
    15961 aaaattttct gctttcttat ctaatgcttc agtaaatctc ttaattttga taatcaagtc
    16021 tatctggtcc ctattcaaat caacttcgac tttatcaata catgctgtat taaacacaga
    16081 tgctgtatca gttagattat ccatttctat atcatgttca aatggaattt cctcactaat
    16141 tttataaacc aattttaaac cttcaactgg gacaaataaa atttcaactt ttatgattcc
    16201 ttgtataatg cttttatttc cttcaatata actattttct atagacatgg ttggacaaac
    16261 gcttacaata tcttttattt gtatatcatc attatcattt cttatgcctt ctctaaccat
    16321 aaatgtttct tcactacgtc ttaaagtctt atttaattga ataggtttgt ggtcaaattt
    16381 tattatcttt tgaggcgaat atgcatcttg taatacttct cttgtaactt catctgtaac
    16441 ttttacctta caacaagcca tacaatctat ttctaaaaga cctgtgttgc tttcactatt
    16501 ttgcttgaaa atatgattaa aatctgacat agacaacaat acttcttcag tcataccatc
    16561 actaactcca gggacttcta caaattgagt aaactcaata cctactctat ccaactctac
    16621 aagttcaccc tcatatgtac aagctaacgg atttatttct aatactccac caataataac
    16681 tttattgtca gtcactctac tttcttttac tttaacacat ggatttaaac ttattataga
    16741 ttgaatttcc tctgtgttta ttgttatagt atctcttata gaactttctg ctttttctat
    16801 tccaactata tcttgaaaac aaatttcctt tctgtgcttt tgtatgcctt ccacttgcgc
    16861 cacatctttt acaatgtcta acctttgctt ttcaaacaaa cttcccctta tattcataag
    16921 agctcctact ttaatctttc tctcattcat tatagtacaa tccatatgct ctacttctga
    16981 aaataacatg tattccatat cttgaacaac attgtctttt tctattactt cgtttatatc
    17041 tacttttccg tctacattag aaatagtatt tttatcatct gcaatataga ttacattata
    17101 attaaaacta cctctgcaaa gtatcttccc atctgccatt tcaatttttt taagtgatat
    17161 gtatccttct gtttttacaa tttcatatac atctaatttt ttgtctggta caactgcctc
    17221 cgcttcaatg aatgtttgaa attttccaaa gtctattcta ttgtcaactt taattacatc
    17281 tttaattaat tccatagtct acctccttaa gtattataaa aatatcacac tatatttata
    17341 tttaaggagc aaaaaaaaaa ttacacctat ttttaaatag gtataatttt aacttatttg
    17401 taatttatct tgatctctaa aaacttgcaa ctttacatta gatgttaata aatctgagta
    17461 actataagat actctaggat atccattact ttcatcatct aactttataa caaacacgct
    17521 tggataaact ttttctagta taccctcttt tgtaataatc tgctttcttc ctttattagc
    17581 tttcaacaat attttctttc ctatatgtct ctctaagctt actcttatct tatctagagt
    17641 ttgaacagta gccacaatat caccttcttt aacgtttata tgtttacata atatcacata
    17701 taaacatttt tgtcaaatgt ttaaactaat tattttatat attttttgca aaaatgtcaa
    17761 tactattttt gaagatatac agtataatta tgttaatttt tgctaatgta atattgtttt
    17821 tggcattgcc catctaaatt ttcctcttgt ttcagaacca ccaattccct taacacctgt
    17881 aatagtctgc tctataacct catcaatagg aactactaca tcaattcttg aacaagcaat
    17941 tttctccact ataaaaacag ggtctaatgc atgtatcatt attcttccag gcgaacttgc
    18001 ataatttgct cctgcactta ttattttttc ataatttgat tggcatgctc ctgcgaatat
    18061 gacaagatta tccaaatttg gttgccattt acgtgcttct tttactgttt taacaaaatt
    18121 tgaagagttt ctatagttac tcatatcttc tatatctcct ctttttattg tcattgcatc
    18181 atgacctgtt attactagta tatccggatt atatttttct agtagtgctc ttacttcttt
    18241 atactgattt tgctctgaaa cagctacacc tactgcaggt attccaagtt gagcatatac
    18301 atccaagcaa atttttaaat attctttatc tccatctatc tgtagtactt ttccaggcat
    18361 tccatatgtg ttaggattta attgaagttt tggaactgct ctagtcattc ttttttgtct
    18421 ttctttagct tttcttactg acttatataa taaattttct acatttttat ctattaatat
    18481 atcttttata tcaggtgctt ttactaattc taggtcatca atataagcat ctgctattac
    18541 tctaaatgca attcccttta gtatagctat tttctcatta ttttcatcta caccaaaaga
    18601 gactatttta aatactatat ctttgttatg tgactttcta gctacaatgt ctcctacctt
    18661 catagttaaa cctccaataa atttttatct tagtttatac tatgttcgat ataaaacttt
    18721 gtttcctaat gtcaaaaaaa catttcttat aatacttctt ttatcactct taaagcattt
    18781 ttatagtata tcttttctat atcatcttca ctaaaccctt ctttttttag aggttcatac
    18841 agtttaccca tctgagatat atcttcaatc tcaacttttg aatctattcc atcaaaatct
    18901 gaccctaggg atacaacatc tattcctcca acatttacaa tatgttttat gtgtctaacc
    18961 atatcttcaa gtttactttc acttttatca cttaaaaata agtggaagaa gtttatacct
    19021 gtaactccac ctttatttgc taatacttta atcatatcat cagttaaatt tctagaatga
    19081 ttcatcattg ctcttgaatt agaatgtgta gcaattattg gtttagaaga aatctttgca
    19141 atttcataaa atccaccatc tgaaatatga gaaacatcaa ccaacattcc caattcattc
    19201 atcttatgta ccacttctct tccaaaatca gtaagccctt tttctctata ttctacttta
    19261 ttatgaggaa agctcaattc attcacatga ttccaactta ttgtcatcat tctaacccct
    19321 aagtcgtaaa atttctttaa attttctaat ttaccttcaa gtactgcacc ttcttcaata
    19381 gataaaagag ctgtaagttt accttctgat tggtttttca taatttcttc atagttagta
    19441 gctaaagcta tttcatcact attttttttc atttcctcat gaaatttatt tgccatactc
    19501 atgcaataat caaaaggatg ttttacttct tcagtatcaa caaaaagagc aaatgtttga
    19561 gctaatgaat cccccttttt caatctgtct atatcaacag aatatttatt agacttaagt
    19621 tcacttgttt ctacattttc cattaatttt gctatagtat cacaatgtaa atcaataaat
    19681 ttcatattta taccccctgt atattttata tttatatcta aaaatagaaa tagttgtcct
    19741 tatagacaac tattgacaac tattttttaa tattcttttt aatattactt aatcttattc
    19801 ttcttttaag ttaggtatta cttttttaac ttcttcaatt tgatgccatg ttttatctat
    19861 attattttca ctaatatatt tttttaaatc agttaaagat gtaaaatctt taactgataa
    19921 attgtcatca tcatctgcaa atcttaaaat aaacatgaga ctcccttact ttccacaaca
    19981 tttcttatat ttttttccgc ttccacatgg gcatgaatca tttcttccta tttttgcttc
    20041 tttaactatt gttttagact tcttataagc ctttattatt tcttttcttt ggtctgctgg
    20101 tagtatatct tcccaacctt gtaaattata tagccaatga gcctcaacag ttaccatatt
    20161 gttatataat ttttcccaat ctatttttat agaaacttct ttatcagctt ctacttcttc
    20221 taaaactata tcttctttta agctttcact tattccatct atgaatccca tgaaaaattc
    20281 attagtagtt ccaaattttt cagccaattc acttacttta ccttcaacaa catccatttt
    20341 attatttaat atttcattgt atattccagc ttcaactttc aaatattctt cccagaattt
    20401 tacttctgct tcttgacttt catgattatc acttaaattt ctccattcag tatataaact
    20461 catacttttt cctcctaagt atacctatat ttttatagtt tttatagtat aaaatctttt
    20521 agttagattg gaagtttctt ctttttgatt ataccatatt ctatttaaag ttaactctta
    20581 tattatatca taattaaaca attcttttaa tacttttata gcatactctt ggtttataaa
    20641 ataagggctt gtcgcaattg ttattacttt ggctttttta attaagtttt ttatcttgta
    20701 aaatttgagt tcaaatggta tatagtccat atcacttgaa aatatatcca aatctatatc
    20761 aagaacaaac tctgattcta cttctaaatc aaatccatac agactatcta ttattattaa
    20821 ttctgaaaat atgttatatt ttaaagcagg ttttataaaa cttcccacat ttaaaacttc
    20881 atttgtatac ctaaatacat cttttagatt atttacatct acatcatagt tctcaggctc
    20941 tctagtatcc ttatgttggt ctacatgcac taacttgcat ccttttgtaa attcaccctt
    21001 taacaaagat tttgcccaaa aataaaatgc atggttatga ttgtcaaaca catatatctt
    21061 tttatttccc aggacatatt cgaccatatt ctccaatcct tttgctttta tttccttatt
    21121 ttcatctact tcattaaata ccacctcatt gcctaacctt acatcattta atgtaccatt
    21181 tataagtttt ggaacgtata tgctcttatt ttctctttta tcatatgaaa atacattatt
    21241 tcctactggt ttttctatat aaaatccact atattcataa ttttccataa aactttattt
    21301 cctccattgt tatataaata tataagttat aattttaaaa attaaaatgc acttattgta
    21361 aatcatatta tctattatag aaaacatctt atataactaa atataatatc ttctctcaat
    21421 atgtattata caataagtgc aaaatatatt tatataaaat atactacatt cctataacaa
    21481 aaccatcagc ttcaattgga aggtaactaa ctcttctatt caactccacc tttccaaaaa
    21541 atactaccca atatggtcta aaaatacttt caattttaac tatttcaatc tctgggattc
    21601 ctcccataaa cctatgaatt aatctcatag ccattttatt tgcctttgct tttactcttc
    21661 gttcgtcctt attactatac tgcacaatat tacaatccac attttttaca atttcatatg
    21721 taggaaaatc ttgtactata ctaccagaac ctgtagaacc attcactaaa atttttaatt
    21781 catttatatc attagaatat ctcctattct tgaaaatgga tttcgttttg tgaattttaa
    21841 gtgtgataat tttaaactct atataatgaa gtctaacttc atgagcatat ttgttcttta
    21901 atattagctt actaaataaa gaatttttcc cacttttagc tatctctata gcttcttctt
    21961 ttgtaattct tataggtaac gctcttatat ccataaaatc attctctttc ttattttttt
    22021 cttgtcattt ttaaaactct atatatataa tcaaaaaata ttacaattac aactgccata
    22081 actccatatg gaattatttt tccaactata atatcatttc tagtcaatat accataaaat
    22141 ataaatcctg ttattaaaaa gtacaataat actagaaaac cgtctactcc aagccatttt
    22201 atttctaaat ctttttttac cttagacact aatttagaca tagcagtttc tccttttata
    22261 gattattttg tgtatttaaa ttttcaccta ttctattacc aatcatccat gcaataaatg
    22321 aaaaaggtat agctatcaca agaggctcta actcaaagct ctgaactgga aatattttaa
    22381 aataaccaaa agtcactcca cctacaatca ttcctaaaat accacccata gatgttcttc
    22441 ttccatttcc aagaagccca cctactatag gtacaaatgc cgaacccatc caaatacttc
    22501 ctacaaatat acatgcatca tatacatttt caaatctaaa tgctacgcta agccccataa
    22561 ctgctgctaa acatacacct attctagtaa actttactaa ttgtttctga gataactctt
    22621 tttttgtaat tcttccatat atatcatttg ctaatgtagc tccagctgct agataatagc
    22681 tatccaatgt tgatattata gaacctaaaa ttcctattat aaatattact cttattcctt
    22741 gtggtaatgt atctaaaact aaagttatat atccagcggc tggagccatc tctggataag
    22801 tagctcttac tataagtcct gttatagtta acaccatgtc aaaacatatc catagtgaaa
    22861 aacaagttaa taaggctctt cttccaacct taggagaatc tgctgctgaa aatctttgat
    22921 aaaaagttgg gtctgaataa gctccaaaag aatatacaat taacatcaat gctttcatag
    22981 ctgacatacc ttttgtaggg tgcataagct gtggtgcatc tttgagtgct tctgtgagac
    23041 cttgaaatcc tcctatttgt tcaaattgac ctggcataac catagttaaa ccaaatacca
    23101 tacaaaaaaa caataccata tctgtaatgg caactcccat aagcccacca agtactgtaa
    23161 gtacaacgac tactcctacc attattaatc ctattaattc tttatctatt ttccatgcta
    23221 cgttacctat agttcccata gcagttattt ctccaagttg tgcacaatat ataaacatca
    23281 aaattgcccc aattatagca acatgcttac cataaaaact ttccagtaaa tcaggaactg
    23341 ttatattggt tcttatatga atccttggac caacccacaa tgctaaaggc attctcccaa
    23401 tatgtgcagc tattgaccaa actgcccatg cagatattcc atatatagcc gcatactcta
    23461 cactacctac tgtaccaact cctccatacc atgatgcaac caaagttcct actattaagg
    23521 accatggtaa acttcgattt cctaggtaat aactttccat atcttttaca tttctagaaa
    23581 aataataacc tattcctaat aatataaatg caaatataac tataatccca ttttcccaaa
    23641 atgttaacat atctaatctc cacattctta tattttaatt tttaacttta atatctaaat
    23701 atgaacaact ctacccattt ccataaaaat aggtagagtt atataataat tataagtatt
    23761 taagtaatct tgttattaag caattttatt gtttaaacct ttattttctc ttttatttat
    23821 tttatttaaa gcataagtag caaatatccc tataactgca catactacag ataaaataaa
    23881 tatatatgta tatcctgttt gtccatattt atctaaccaa ttacctgcaa tagtgtaata
    23941 aaacgcatct ggagaaaatc ctataaatga agcaaatcca actactgctc ctgtagtttc
    24001 taaagatata ttagactctg aaacagatgc aaagtatata cctctaaatc caaataaaat
    24061 tacacttagt attatcatgt ttattacagc tatccatata aatcctgtac tcttaggaat
    24121 aaccaagtaa gcagctgtac ttactgtcat taatataaat cctacaaaca ttactcttat
    24181 agatgaacca actttatctg ttataacacc agcaactgga gatgctccca tttttataac
    24241 ataagttctt attattgata aagcagaaac tagagtcatt ggcattacat aaacttctga
    24301 taagtatgga cttaaataag ttaaacttga gaatactaaa taagttgaaa atattataag
    24361 accaattaac caagcctttg gcattgtaac tacttttaac aatgacttaa tacttaatcc
    24421 ttcatctgat gctccactat cttttttctc ttccactaag aaaaatagaa gtataccaca
    24481 tattatagat gctgcagaat ataaccatac tacatatttg aatcctactg ttatttcagc
    24541 aaatttacca aagaagtaaa gacctataaa agaaattaac gtacctgata cacctgataa
    24601 cccttcataa aaaccaaata ttcttccttg ttctgactca cttccttgca ttctaacaac
    24661 cttaacagat gctgagaaga aagttaatat tgttgtaaat ccccataata caaatattaa
    24721 gagtatcata ctatatgatg ggaatgtaga gaaataaaaa ccaagtactc ctgaagcaat
    24781 taaagaaaaa gttatcagct ttctaaccga gaatctatct gcaaaccatc ctcctataaa
    24841 ataagatacc attcctacta atccatataa actcaataag ttccctattt gtgtatggct
    24901 caatgataaa gcttgttgca ttgggtcata aaatgatgat ttcatatatg gtaaactata
    24961 catagccgtt gttccaaatg ccaatatgaa tattatcaag aatcttttaa aattactttt
    25021 gttctccatt aattttctct ccttaaaatt ttattgttta taatctcatt catgtaattt
    25081 tattttaatt tttttattgc ttgtttaaag tcatttatta tatcatttga agattctaat
    25141 cctacagcta ttcttattag attttctcca ttcatttgaa ctaatgtatg ctcttcccct
    25201 aagcttgttg ctattgttgc aagctctaaa gagttcatta attttctact agcttggtct
    25261 cttgtcaatc cattgatacc atccttaagt ttaaatgaaa ctacacctcc acctaaacca
    25321 ttcatttgag ttttacaaag ctcatattga ggatgagatt ttaatgctgg atactttacc
    25381 aattccacat tctcttcttc ctctaaaaac tctgctactg ctaatccatt ttcacaatgc
    25441 tttttcatcc tcatatctaa cgttttcata cctcttaaaa tcatccatgc actcattggt
    25501 ggtaaagatg ctcctgtaaa acaacataaa cttggccatc taactaaatc tattaattct
    25561 tttgaacctg ctactgctcc ccctaaagta tccccatgtc catttataaa cttagtaaga
    25621 ctatgtatta ctaaatctgc acctaaatct attggtcttt gtacaattgg tgtcccaaaa
    25681 gtactatcaa ctatagctaa gcttttattt tcatgagcaa tttctgctat tgtttttata
    25741 tctactaagt ctaatgatgg atttaaagga ctttctatat aaactatttt agtatttggt
    25801 ctcattgctt cttttacatt ttgtggattt actgcatcta caaatgtaac ttcaactcca
    25861 aatttagata acaactcaga catgaataat ttagtgtgtg aaaatattcc atctgaacta
    25921 actatatggt caccactttt taccaatgct aatatagtag atgttattgc ccccatccct
    25981 gatgtactag atatggcact ttctgcattt tcaagcatag ccaacttagc ttctaactct
    26041 gtaagagtag gattacactc tcttgtatac acatatcccc atgtcataca caactcttca
    26101 aaatgctcta ctgtctttgc agcaaatgtt gctgtttgac atattggtgt agccaatgca
    26161 cctgttgttg ggtctgcact atgtccccaa tgtattattt ttgtctctaa atcttgatta
    26221 atattgttac tcattttgat ttcctcccat tttgacttat ttatacaacg ttttccctgc
    26281 caaatttaat caatttagct tagtcttaat acattttttc aagtatactt ttttatttgt
    26341 tataatttct aaaaatatga cacttatttt gtttttttac agttctaatt ataaactcta
    26401 tagtaactat agagtcaata tgtttttgat atttttttta caatgtttaa aatagtcagt
    26461 acaaaaatag gtatatctta gaataactaa agtcatccta agatatacct atttttatat
    26521 cacaatataa ataattacat ataagcatta gtttttttat cataaataga tttttcaaga
    26581 tttatcatct tttcataaat atattatagt taaatatttt aatattacct aacatctaca
    26641 ataaaatata ctcttaaaat aaaattatat aattaaaaat actctataaa agctaaaaag
    26701 ttttctattc gctacatcta aaaataatta gatagaggta taaatgtatt tagtttattt
    26761 atacctctag tcttttataa attatatctc tactaaattg attttttagc acgaataagt
    26821 gtgctcttgg agataccagt catcttcaca acctctctat atggcttaga atttaataac
    26881 cccaatgcat attgtatctg ttgattgctg tatttctttg gcctaccatc tttaaagtcc
    26941 tttttctttt tagcaaattc ttttcctaat tgagtacgtt ctattatcat atttctctca
    27001 agctctgcaa ctgcaagtaa tgtagtcaaa aagaatttac ccattgaagt attttctaaa
    27061 agacctatat ttaaaatatg aacacttact tctttagcaa ataaaccttc tattagttgt
    27121 atcccttctg atgtacttct agctagtcta tccagcttag ttgcaacaag taagtctccc
    27181 ttttttagag atgatataat tttttcaaat ttaggcctgt ttgtagtagt gcctgtataa
    27241 gtttccttta ttattttagc atcattatat ttattcaaaa tttcttgctg ttgctgatac
    27301 aaactgttgt tgtctgtttg attttttgta cttacacggc aatatccata tataataatc
    27361 atcacttcct aacataaaga ttttgtacag aagttaccca gaagcttgtt tttacttatc
    27421 tttatccatt ttactaaaac gatttttggg tgtcaatact gttaactttt gacaccataa
    27481 taattccttt ataatttgtt tgactatgtc aaaaattacc aatataatga aattaatgag
    27541 tttatacaaa ttggaggaaa taatatgaat agtctgttaa aagaagcaat agatgaatta
    27601 aaaaacatcc attgcgggga agttttttta ttaaaagaat tgttcaaagg ctatgaatgg
    27661 aacaggttgg agatgaatat tagattgaaa ttaggaaaac tttttttgta tgaagtggta
    27721 actaatccca atttaaatgt agaggtcatc aataaaaatt ctgcttatca gcaaatgtat
    27781 aaaaaaaaat agtgacttaa atgtatataa tagtataatc ttcttattga ttcaaaagtt
    27841 aaaactttta atacaaaaca atcattctat tttaacattt atcaatatgt ctaaatttat
    27901 ataattaaca catacgaata gtattgttta aatcacatta tttaagatag ataaatctta
    27961 accctactcc agcataaata ctaaaatagg gcttagaatt atctatattt ttatcccata
    28021 aaatgcttag ctcttcctct tgattgaaca tatatatctg gggaaataca atagaagcgt
    28081 aaatttataa aatttccaaa gtcagaaaac ttcagttcaa acttaggtat accaaaactt
    28141 tcaggtgcta tttcatcaac gccaaaatag atgataattc cattatctgt aatataaaat
    28201 gcttggtctt caggtataac taactcaaca ttagaataat acatttctct attttcattt
    28261 atttgagatt taatgtaatc agtaattata ttaatataat caactccatc tctaaaaatg
    28321 tcattaagta aaagttcttt tccagttgtc aaatctatat tgtaattatt caatgtattg
    28381 tatttaggcc catagttatt agcaaacccc ataaggttta atatcatact cagtacataa
    28441 tttttattaa aagtaactgc gtaactggta gatacccaat agctttgttt tggaagtgaa
    28501 ttttgagaag ctgcgttatt atattctcgt tcttcttcct gtaagccatt tttaaaatta
    28561 tttacagtca ttcttacagc attgtttatg ttatttaaaa taactgggtt tacatacgtg
    28621 gattgatttc taatattgta tataacagga tactttacat catatgaaaa atacttactt
    28681 ctttcaaaat cttcattaaa ttgtacatat aatatattat atgtacaggt atttgtagat
    28741 tgataatttt ccattaaaat cctccccctt ttataaaaaa atcagataca atataatatg
    28801 cttaaaacag taataatgtt aatagtaaat gtaaagaata gaaagtatct aaaacagcaa
    28861 aaaatgacta attttgtggt ataatacata ggattgagag ttattttata ggaggaaaaa
    28921 tatgttatta ttagcagata aatggaaaga ttatgaactt atagatatgg gaaatggaga
    28981 aaaattagaa cgttggggaa gttatgtact tagaagacca gacccacagg ttgtatggcc
    29041 aatggaatct gaatgggctt tatggaaaaa ccctcatgga cattatcaca gaagcaataa
    29101 aggtggaggt caatgggaac acaaaaaaag atatccagaa caatggacta taaattataa
    29161 aaacttaaag tttcacatta aaccaactgg ctttaaacat actggattat tcccagagca
    29221 agcagctaac tgggattgga tgatagagaa aataaagaaa gctaacagac ctataaaagt
    29281 gttgaatctt tttgcatata caggtggagc tactgtagca tgtgcatctg ctggtgcaga
    29341 agtatgtcat gttgatgctg caaaaggtat ggttaattgg gcaaaagaaa atatagaatt
    29401 atcaggtctt aaaaatcaaa cagtaagatt tatagtggat gatgttgtaa agtttgttga
    29461 aagagaaata agaagaggta aaaaatatga tgcaataata atggaccctc cttcttatgg
    29521 aagaggtcct aaaggagaag tatggcaaat agaagaaaag ttatacagtt ttgtagattt
    29581 atgtatggga gttttatcag ataacccttt atttttctta attaattctt atacaacagg
    29641 attttctcca atagttcttg aaaatgtatt gtctacaaca ataggtaaaa agacaaatac
    29701 aggagatata tacggtgggg aattaggaat accagcttcc agagatggta agatacttcc
    29761 ttgtggtata tttggaagat gggagaaaaa ataatgataa aagtcatata tgaagataac
    29821 catttattag ttgtagaaaa accagttaac atattgtctc aaggagataa tactaatgat
    29881 aaagatatgg taaatctttt aaaagactat attaaaaaaa agtataacaa acctggaaat
    29941 gtatatattg gtttaataca tagattggat agaccagtag gtggagttat ggtgtttgca
    30001 aaaacatcaa aagcagcatc tagattgtct gagcaggtaa gaagtaagac tttcaaaaaa
    30061 acttatctag ctgttgttca tggcaagata aaatctaact cagatatact aaaagatttt
    30121 ttatataaaa ataaaaaaac taatatggta actgtagtga aaaaaagcca taaagatgcc
    30181 aaagaagctg aacttaacta taatgtatta gattttaaag aaaatctaag tttagttcaa
    30241 gttaatttaa agactggtcg ttctcatcaa ataagagttc aatttgcaag cagaaaacat
    30301 ccattatacg gagaccaaag atatggcaaa gaaataaata agattggaca acaaatatct
    30361 ctttggtcca ataagataga aatttgccat cctactacaa aagaaaaaat ggaatttaca
    30421 tgtcatccac ctgacaaata tccatggaat atattttaaa tctcaaatga ggtgattata
    30481 tgagtaaaaa attttcaata ggagaaatgt ctaaacttca taaaataagc atacagacac
    30541 taaggtacta tgaccaaata gatttattta aacctgttca tgttgaccaa gaaagcaatt
    30601 acagatatta ctcaattgac caattttcac aattagatat tataaaatat ttaaaatatt
    30661 taggtatgcc tttaaaagaa attaagtcaa agcttgatga aaataatgaa gaaattctaa
    30721 aattactaac aaataaaatt aatatagtgg atgaaaaaat taaagaatta gagcttataa
    30781 agaaggtact aagcacaaag aaagaaacta tggaaaaagg tatgaaagta gatgaagttg
    30841 gtaaaatagt gagaaaacat attccacgaa gaagtatctt atctatagag tatgaagaag
    30901 gattaagtag tgaagaaact atggaacttt ccagaagaca aatagcaaat atattagaag
    30961 ataatatatc tgtgttctat ggtggagtaa gtggacttgt atctatagat aaatttttaa
    31021 aagaagataa agttatttat gacaatagtt ttgttactgt tgaaagagac ttatttgata
    31081 taaaatcaca aaaacatata acagaaattt catctggtga ttttatttgt atgacatata
    31141 aagggtctta caaagaaaat tataccgctt ttaagaaact ggttgattat gttgaatata
    31201 aaagaatacc tattgaaaat tatatatatg aaatacctat aatagaccct ctgtctacaa
    31261 acaacgaaga ggaacttcta acagaaattc aaatacaagt taaaaagaga gaaattgact
    31321 taagatgtct agtgtagtaa tctagtttac ttacacatct taatatagtt gtctattatc
    31381 aacatatgat ttttctagat agtgattcct aacagtgaga ttttcaaaaa ataggaggaa
    31441 atatggctaa tgctaattcc ctcctatttt taattaatcc atatcatttt aattaagcca
    31501 tgtcatcacg aagtgcatca ataatatttt ctttttttat cttattaata gtatacaaca
    31561 ttgtaataaa tactataaat aaaacactaa atatactaat tccaatacta aaccatggaa
    31621 tcacaaaatc aatatcatct gtaaccatta ctttatgaat tagccatgaa gaaattactg
    31681 ctataggaag tccaaagaac aatgctctca tgccataaaa agcacactca aaattcatca
    31741 tcttttggaa atcatgctca gacattccta cagagcgaag catggcaagt tctctacgac
    31801 gtaacttaat attagttgaa attgtattaa acacattggc aatcgaaatc agagaaatca
    31861 taattatgaa agtataggca aaaacattgg caataaaaat gtaattacgg ttctcatcca
    31921 tcattccata catattgtac agattgtact cattagtaac tccctcactc tcaataattt
    31981 gctccatttc tgcaactgac tgagtaggat ttttcgattg aaagcttaaa ctttcaattc
    32041 ctgtagaaac accaggaatc tcaaacttat ctttggctga ataaggagcc aatactctga
    32101 agcttgcttt cttcacatct gaacttctga ttcctggagg agaatcaggt ggcactactt
    32161 tgacaaatga aatattcaca ttttgtctct caggtatctc caacttgcca ttagtttcag
    32221 gagtgagact aacattcata gaagaactgt tgaaaatatc aataatatta ttatcctttg
    32281 ttaccataga aacagcaatc agttttgcat tttgtccagt atattcttct gctggtaatc
    32341 caagactttt aataatattc agataagttc tatcatcaag aaattgcata tctactggta
    32401 attcaagcat ttcactcata gaatgtgaac cctcatagtt caaataatcg tctgtaagct
    32461 cacttacttt ggcaacacat gaataggtca taagtttctg atacaaacct tcgtaaacac
    32521 catttgcagt ttttagctta tcgtaaagct tcaacatttc gttgtctttc ataccttgtg
    32581 tagaaaaaat aatatcctga tcagtaacct ctgacctctg atttgacatc tgttttaggt
    32641 ctgctactaa agcacttgta gatataaata aaactatgct taaaacaagc gacaatacaa
    32701 tacttcgata acgtttcttg tttcttttaa agtttttcat agcaagaact ccctcaagac
    32761 cataaactcg ctgtgttagt tttgatgtct tcacagattt agattcaatt tttacctcat
    32821 ttgtctgacg aatacactcc atcactggtg tgttggcagc ctttcttgct ggtatgtaag
    32881 cagaaattaa gattgtaacc atacttacca ctgctgcaac gatgattgca gggatagaca
    32941 atgttaatgt caacggaacg tttacataga gaatatttgc aaagttttta gctatgacag
    33001 aaatcacaag tccaatactg actataccga ttgcaacacc aattggtata ccaatcgcac
    33061 caatgcaaat tccttcaaat agcaccgaat ttcgtaactg ttttgctgta gctccaacag
    33121 atgaaagtat tccaaattga tgtgttcgct cgttcaatga catgttaaat gaattatata
    33181 ttagaaaaat tgagcctagc atgattatgg caagcacaat gccaccaacc gagtacaaaa
    33241 acatattgaa caaattgtta tcagaaacac ctatgaagcg caacacattg tcattgaaaa
    33301 tggaagcatg gtctttagtg ctacttgtgt aagagcgaat ctgatgtgga tttttcaatg
    33361 tgacaaaaag gctaagactg tcagtcttga cttgtttatc ttctttggtt atcaaggtat
    33421 atcctggtgc agaagattct tcaaatacgg gctttctaca gatacccaca actgtataag
    33481 ttttcttatc ctgtggcaca aaaacttcac tcccagcagt gtaggggtca ctctgaccaa
    33541 gcttttcatt ttcactcatt cgtttcccta catccaaaga aatagtatca cctactgcaa
    33601 atttgacacc accatctgtc gcaactttac ttgaaacaag aatctctcta ctattttcag
    33661 gtaatcttcc agaaattaaa gttataggca aagtatcaaa agcttctttg ctaaatccag
    33721 caataaaaag atatggttta tctggatttc tgttaccttc aagtgttgca tagccaatat
    33781 tttcaaatgt tgcagtattt gcaacttcat cattgactct ttgttcctgt acaaaagaag
    33841 aatccacatc caaaaactgg acatgccaat caccatattt tataatagct ccatttgtca
    33901 tatagttcat caaagaaact ccaaaggtag taactgctgt aatcatagca gctgacagaa
    33961 caactcctat aattgttaca agagttcgag tgcgattctt tttcaatcct tgcagagcaa
    34021 ctttgttaaa aatgttcatt aacgattcac cttcctctca tcacgcacca cttttccatc
    34081 tgaaatacag ataattctat ctgcctgtaa agcaatgttt tcatcatgtg tgacaataat
    34141 gagagtttgg tgatatttac tatggctctc tttcagtaac tggataatct cttgtccatt
    34201 tttactgtct aagctacctg taggctcatc agcaagcata actgctggtg cattcatcaa
    34261 tgcacgacca atggcaacac gttgctgttg gcccccagaa agttgatttg gtaaatgtgt
    34321 ttttcgttct tttaaaccaa gtaattctaa caagtcattt aaccgttctt gattgacctt
    34381 acgcttatcc ataagtatag gcaatgtgat attttccact acatttaatg tgggtatcag
    34441 attgtgaaac tgataaatca atccaacttg tcgcctacga aaaatagcaa gtttttcatt
    34501 gctttggcca tatacatctt gcccctccag atatatcttt ccacttgttg gtacgtctac
    34561 tcctgcaatg gaatgtagta gtgtagattt accagaacca gaagaaccaa tgattgcagt
    34621 aaactcccct ttttcaatag taagtgagac atggtcaagt gcagtaacct tattttcatt
    34681 cttaccataa accttacata aatcttcaat ctttaaaaac gccattatat aagtctcctt
    34741 tcatatttta taaatatatc atagaacttt caacttacat ttaagtgaca tttaaatgag
    34801 agattcgtca ctttggaaaa cgaataacaa atattgcacc accttgtggg tgattttgtg
    34861 cagtaattgt tcctccttgt ctcataataa tcgtcttaca aagtgccaat cctattccat
    34921 aaccagctgt gcttgaattt ttcccacgat aaaatctgtt aaatagacat ggtaagtctt
    34981 cttttttaaa gcctgctccg ttgtcatgaa tagtaagttg agtaaacaaa aagttgtcct
    35041 cacaaacgat atcaattttt ccattatcac ccacactctc catgcagttt ttaaatatat
    35101 tttgaattgc ttctgaaagc caatttaaat cacccaaaat ccttactcct tttggtatat
    35161 caatatgtaa agtgatattg tgcagttcca tgggaatcaa aagttgatga agtgcagaac
    35221 taatcaaatt attcacatca atttgttctt tttgaaagac tacaatacct gcatctaaac
    35281 gtgataattt taaaagggaa gtaatcagcc agtccattcg tataagtaat tcctctgttt
    35341 ctcgtatcaa ctcttttctc tcatcttcat cagaagtatt ctctaacagt gacaaaataa
    35401 gagttactga tgtaagagga gtgcgaagct ggtgggctat gtcagctagt gagtcagcaa
    35461 ggtgttcttt ttcttttttc agtgcgtaat tttgctctct aatacgtaac gtcattttag
    35521 ttatttcact ttgtagaata gaaagctcac cctcatctga ttcagcaata tacagatggt
    35581 tagcattatg aagcacaaga ttaatttgtt ctgaaatctg tgcaatactt ttgtatcgat
    35641 ttttagtaaa cacaaaaaat gctattccaa aggtagtggc agaaacaata gaaagtattc
    35701 cagtcataat actgattgca aatcccaggg ctacagtgag aatagtaatt aataagaata
    35761 aaatagcaaa ttttcgaaac tctctatttc gaaacataac ttccccccaa tctataccct
    35821 gtcccacgaa cagtcaaaat tatttgtgga cttgaagggt catcttctat cttctctcgc
    35881 aagcgtttga tgtacacagt caatgtgttg tcattaacaa actcacctgc cgcatcccac
    35941 aattcatcaa gtaatcttac cctcgtaata atacttttag gattgctaat aaacaccaat
    36001 aacaaacggt attctaaagc tgaaagaaaa acctcattgc cattcttttt cacaacaccg
    36061 gttgccgtat ctacataaag cccacaaatt tcaaaagttg acccaaaacg cccacttttt
    36121 cgtagtgctg ttctaattcg cgcaatcagt tcacgtggac gaaaaggttt agtaatatag
    36181 tcatctgcac ccatattcag tccagtaaca acacttgatt catcaccaga agccgtcaaa
    36241 aagataacag gaatgtcttg cttttctttg atttctgtgc aaatcgtaaa cccatttcca
    36301 tcaggtaaag aaatatcaat aagtgccaaa tcaaatttat tcttagcaat ctctacaagt
    36361 gcttcacttc ttgtggatac atgggttact ataaatcctt ctgaattaag caaaagaata
    36421 agatttttgg caattgcttt atcatcctca actaaaaata tccgtttcat ttactttcat
    36481 cctcctttat tttattagtt ttatatattc cagcagagca atagtacact actattttac
    36541 ttatcattac acaattttca gtagtttctt ttgttcttat ataatccatg cataatacct
    36601 ccattgattt attatatttc ttataacata aatacacaag ataagacaaa aaacataatg
    36661 taagtgcaag ttttttaact cactaactta taaacataca ctcctactaa cactactttc
    36721 ttgatgacac atcttacaag cttatattca tacatcaatg aaaaattaaa tttatccatt
    36781 tattaaaata aaaggcaata gcttctatag ctaatgccct ttatcttaaa atgatttaaa
    36841 tactatacaa tttttataaa tggctataaa taaactcgta tagaatataa aatttatcta
    36901 cagtcttttg ttatacaaaa tttataacct cttatagaac aaatttacca ctttgtaaac
    36961 ttatcacttt tactcagcta tattataaac ttttaattta tctttgttta aatgtttctt
    37021 cttaacttct actaaagctt ttagcgtatc caaagatgtc attatttcag tagaaaattc
    37081 aatggctgtt cttctcatct taaatccatc tcttgtagag tcatttcctt tagttggtgt
    37141 atttattact atatcaactt gtttatttct tatagcatct aatatgtttg gtctaggctc
    37201 ttcaattc
//
LOCUS       DAMJWO010000040        36072 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.041, whole genome shotgun sequence.
ACCESSION   DAMJWO010000040 DAMJWO010000000
VERSION     DAMJWO010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36072
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.041"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            216..593
                     /locus_tag="PC366_001990"
     CDS             216..593
                     /locus_tag="PC366_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2577518.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDVTVTSKDVIEAMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTIRVKHKDYLSFETKDFLSNIHDDSLRSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
     gene            586..1620
                     /locus_tag="PC366_001991"
     CDS             586..1620
                     /locus_tag="PC366_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HDF2577519.1"
                     /translation="MNNYMLYVFENLIKTTIVCSLGICLLLFLKRYLFKKFSKRFNYY
                     IWLIIVFRMLLFLFNYTIVYEVKEPKENAVGNNITQIDISTDNNLMLYVAYLWLVVTI
                     VIAVYTFIKYTRFKNLVVDVSYDIEDNDVNCIYKNLLKELNIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYPYSKDELTWILKHELMHFKNKDILIKFLVLSVRIIYWFNPLVYV
                     MSNKVNLDCELCCDESVLTDCSLKDKKEYALALIKSIKLSKNYNSGILTTEFNKTSLE
                     KRLDSIVKKKGKNGILVLLILITLFSVTYFNFESISFDNSNSLRNMGILQKSGVDLKE
                     EDDISMRVIN"
     gene            1686..2273
                     /locus_tag="PC366_001992"
     CDS             1686..2273
                     /locus_tag="PC366_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HDF2577520.1"
                     /translation="MKNLKKILIITGCLTLISTSLVFANTTTDVDTSKDDDSIISSCT
                     ITGYEFTYENAPQSVKFDYEKKCEALNIKPSKNDIIFVNKDSIDANDVENYVEPKAYI
                     IRYKKGYVFEVTGPKSYTLNVSNTVVGYNRVESGNPVHLVQLLCRTLDGSSIDDDSEF
                     GPATYNAVKSLQGRLGLTRDGIVGRSTWDAAGRRL"
     gene            complement(2651..3412)
                     /locus_tag="PC366_001993"
                     /pseudo
     CDS             complement(2651..3412)
                     /locus_tag="PC366_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612258.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            4020..4397
                     /locus_tag="PC366_001994"
     CDS             4020..4397
                     /locus_tag="PC366_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2577521.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDATVTSKDVIEVMEQKYGWKQTTT
                     LTLLSRLVKRGFLNAQKIDRYTHYTVIVKHKDYLSFETKDFLSNIHDDSLKSLISALH
                     DDENIGKDTLDFLESYFDNLKNE"
     gene            4390..5424
                     /locus_tag="PC366_001995"
     CDS             4390..5424
                     /locus_tag="PC366_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HDF2577522.1"
                     /translation="MNNYMLYVFDNLIKTTIVCSFGICLLLFLKRYFFKRFSKRFNYY
                     IWLVIVFRMLLFLFNYTVMYEVKEPKENTVGNNITQIDVSIDNDFMLYLVYLWLFVTI
                     AIAVYTFMEYTKFKNLVVDVSYDIEDHDVNCIYKNLLKELDIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYTYSKDELTWILKHELMHFKNKDILIKFLVLSVKIMYWFNPLVYI
                     MSNKVNLDCELCCDESVLTDCSLKDKKAYALALIKSIKLSKNYNSGILTTEFNKTNLE
                     KRLDSIIKKKGKSGILMLLILFTLFSVTYFNFESISFDNSNYLRNIGILEKTGADLKE
                     EDDISMRVVN"
     gene            5903..6076
                     /locus_tag="PC366_001996"
     CDS             5903..6076
                     /locus_tag="PC366_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HDF2577523.1"
                     /translation="MHLVQLLCQQINGSDIDPDSKFGPATYNQVKILQGRLGVTKDGV
                     VGKATWQAVGERY"
     gene            complement(6161..7183)
                     /locus_tag="PC366_001997"
     CDS             complement(6161..7183)
                     /locus_tag="PC366_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF2577524.1"
                     /translation="MNYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTLLNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNSGNGIVFIKPWNNSKIIEKI
                     RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTKLPFIIKGIMTVD
                     DALMAVESGASAIIVSNHGGRVLDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDV
                     VKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETMILTGCQNVKDIDGR
                     VIWNLL"
     gene            complement(7514..7696)
                     /locus_tag="PC366_001998"
     CDS             complement(7514..7696)
                     /locus_tag="PC366_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577525.1"
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFMVKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            8009..8428
                     /locus_tag="PC366_001999"
     CDS             8009..8428
                     /locus_tag="PC366_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HDF2577526.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV"
     gene            8559..10400
                     /locus_tag="PC366_002000"
     CDS             8559..10400
                     /locus_tag="PC366_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2577527.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLTNNDFVENKIGVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAI
                     LSLKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIET
                     LYIKIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSIEYLNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVA
                     INNLAKSEVYLEKIKNQSLKEVEKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     MIKNIEEYTIYDLEIIYHQAKIYYIFGYYDNALNTNKKLLEKSKNAKNYNYVKLAYKN
                     IYLCFEKIQNYEMSMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIETEINNMRKVK
                     LDLDKKKYVDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDI
                     ALKNITIIIKKYLKKDMFMIRYGGEEFLILSVCKDYKKSKIFGRKLCRIVKKFLNNNL
                     TVSIGIDTCKNSSIDIREIIENADKALYKAKESGRNRCLHYHDFKNF"
     gene            10427..12313
                     /locus_tag="PC366_002001"
     CDS             10427..12313
                     /locus_tag="PC366_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2577528.1"
                     /translation="MKRSLIEDLKRNINKIEYDMLTKFYLNLTDLNYILDYHKDLLNT
                     KLEDNSRVYTLYLISLINYIKKDREASYNYLIESLKYIKKLSLKEDSDIISKIYIYLT
                     LSAISIRKYDKANNFYFSAKKVIRQNHLNELLVLLNMSLCVEISALYQTKTDVIALVE
                     EVSFFKTLKNKALVSRANYIFGRVYLYLFNNFIKSMEYLIECLKLAQENNLYSIEAFC
                     KCIISLCYLESGNNVEAIKYINNVLDVAHSKNSISVTERVSIKIDLIWAYLKEDMNKE
                     AEVILLKTIKLMKVVEGVYKDYLYSFIFLYSAEIELRKDNCSFEKVNTYLILSKNIYK
                     SFGDVFIYNSKLDYIYKLYGDLYIKFGNIDEGISCYIKGLNLVKKSSLNLRKISIFYG
                     LIANGYELKKDFKLAIEYYKSMDWYSDRWEKNNSYKTSQAIHKQYELRQKQESLRLLV
                     DDNKKLENDILKDGLTKLYNRRYLEQQLDLFNGTRDKNMVAILVDIDCFKSYNDNYGH
                     LAGDKVIVKVTDIIRSVFIDITEHIIRYGGEEILILVDSIESIGVEEIDNIELYIKRV
                     FKLLEFEGIEHIYSKIKNYITISAGVSIKRCRSRKDVEILIEDADKNLYKSKKAGRNQ
                     YIII"
     gene            12321..14321
                     /locus_tag="PC366_002002"
     CDS             12321..14321
                     /locus_tag="PC366_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2577529.1"
                     /translation="MILLRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEVVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTREFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            14583..15842
                     /locus_tag="PC366_002003"
     CDS             14583..15842
                     /locus_tag="PC366_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2577530.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLVLVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVEEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINN"
     gene            15903..17690
                     /gene="iorA"
                     /locus_tag="PC366_002004"
     CDS             15903..17690
                     /gene="iorA"
                     /locus_tag="PC366_002004"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HDF2577531.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNET
                     DLNYYEMNDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            17692..18267
                     /locus_tag="PC366_002005"
     CDS             17692..18267
                     /locus_tag="PC366_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HDF2577532.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            18320..19390
                     /gene="buk"
                     /locus_tag="PC366_002006"
     CDS             18320..19390
                     /gene="buk"
                     /locus_tag="PC366_002006"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HDF2577533.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGQYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            19608..20309
                     /locus_tag="PC366_002007"
     CDS             19608..20309
                     /locus_tag="PC366_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577534.1"
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKRSN
                     EHKCKSSIVIKNEQN"
     gene            20368..20874
                     /locus_tag="PC366_002008"
     CDS             20368..20874
                     /locus_tag="PC366_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HDF2577535.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEMYELLYE
                     IDNNKLNI"
     gene            21049..22071
                     /locus_tag="PC366_002009"
     CDS             21049..22071
                     /locus_tag="PC366_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF2577536.1"
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAVETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(22218..22526)
                     /locus_tag="PC366_002010"
     CDS             complement(22218..22526)
                     /locus_tag="PC366_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HDF2577537.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK
                     "
     gene            complement(22586..23014)
                     /locus_tag="PC366_002011"
     CDS             complement(22586..23014)
                     /locus_tag="PC366_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577538.1"
                     /translation="MNNKLHELEKNLPETSCSFCTHLSFKGPSLDYRYDIRCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFKCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            complement(23237..24694)
                     /locus_tag="PC366_002012"
     CDS             complement(23237..24694)
                     /locus_tag="PC366_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HDF2577539.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNI
                     NISYVLAAIFTVLYAILTVRSGRKLKSKADTKLAD"
     gene            25112..26026
                     /gene="nadA"
                     /locus_tag="PC366_002013"
     CDS             25112..26026
                     /gene="nadA"
                     /locus_tag="PC366_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HDF2577540.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKLLSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            26039..27340
                     /locus_tag="PC366_002014"
     CDS             26039..27340
                     /locus_tag="PC366_002014"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HDF2577541.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFIDVPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            27321..28157
                     /gene="nadC"
                     /locus_tag="PC366_002015"
     CDS             27321..28157
                     /gene="nadC"
                     /locus_tag="PC366_002015"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HDF2577542.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSL
                     EMAKQAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
     gene            28413..28745
                     /locus_tag="PC366_002016"
     CDS             28413..28745
                     /locus_tag="PC366_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HDF2577543.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPVGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            28907..29092
                     /locus_tag="PC366_002017"
     CDS             28907..29092
                     /locus_tag="PC366_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577544.1"
                     /translation="MSEKYADKLEIKLYQAGKDFSYIKKYGIITKGTLIINQKKKYDR
                     LNKDTIERAIVEAINNN"
     gene            29119..30204
                     /locus_tag="PC366_002018"
     CDS             29119..30204
                     /locus_tag="PC366_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDF2577545.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGPKVTIIYLIAGFLVPFLVGFLGNCFGKEELSLYNDSEEEVIEL
                     EEEKRSFMENMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAALVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSTIPKMKEVIGNHA"
     gene            30197..30655
                     /locus_tag="PC366_002019"
     CDS             30197..30655
                     /locus_tag="PC366_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577546.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            30690..31781
                     /locus_tag="PC366_002020"
     CDS             30690..31781
                     /locus_tag="PC366_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2577547.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKPKEKEEAKAGKDDYTIT
                     VGYYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGA
                     IPKGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLP
                     TDPSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKAN
                     GKEYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEV
                     ALRTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGA
                     DDFDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            31786..32010
                     /locus_tag="PC366_002021"
     CDS             31786..32010
                     /locus_tag="PC366_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577548.1"
                     /translation="MENIKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTS
                     GFVINYMVNRDYFENIKVSDIMDIFTINDC"
     gene            32020..32583
                     /locus_tag="PC366_002022"
     CDS             32020..32583
                     /locus_tag="PC366_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577549.1"
                     /translation="MQWALSSEEIDIAIICKDAAKQYVNVNSGFEIVGTVVQNSDIFL
                     LSDNNPEKIGVIQNRDYQSELVKKYYKNVEVAPLLGTALAYGLESNLVDGVVIDCIKS
                     IGLEGKRKSTTKLGDYDTYVLVVSKEFKKSKAYSDFITLYNKSVDALKNKATFKKALK
                     EYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            32544..33173
                     /locus_tag="PC366_002023"
     CDS             32544..33173
                     /locus_tag="PC366_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577550.1"
                     /translation="MEIKISKDKSDRLTKKKTDGSMDILYKIILLVIIFLVWHFAAKD
                     IGSSLLLPMPVDVIKGFFFCVTDAETVTNLFITLQRVLKGFMYALLFGLPIGFIMGFS
                     KTFERVLSPVVDSVRQVPIMAWVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVR
                     AISKDYYNAARSMGASPIVIFTNVIVPASLPDILTGSRIAISTGWMSVI"
     gene            33213..33350
                     /locus_tag="PC366_002024"
     CDS             33213..33350
                     /locus_tag="PC366_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2577551.1"
                     /translation="MVQAQTLMHTDVLIGLMIFAALIGFIIDRVLKFINKILCRWRFA
                     D"
     gene            33350..34102
                     /locus_tag="PC366_002025"
     CDS             33350..34102
                     /locus_tag="PC366_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577552.1"
                     /translation="MKLSVRDINKTFVNNRVHTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSERGDVFINDKRVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEVLLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            34115..34600
                     /locus_tag="PC366_002026"
     CDS             34115..34600
                     /locus_tag="PC366_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577553.1"
                     /translation="MSQIEKYNSLDNTQQKIRISIMDMIIDKGSSVTLQEVTEYVSKK
                     LNIEKEYIERTLQYFIYENIMVVDGNSINFIYPVSALQTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDIKINSICSATGKEIEVIIKNEKIEYVNNPNLRVLHINLDKHLNWAAS
                     C"
     gene            34607..34756
                     /locus_tag="PC366_002027"
     CDS             34607..34756
                     /locus_tag="PC366_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577554.1"
                     /translation="MNFFWTKSDFDAWTNEAGLSDDEDIYCLDINEAIVESYKIFKLK
                     QKVLS"
     gene            complement(34892..35713)
                     /gene="yidA"
                     /locus_tag="PC366_002028"
     CDS             complement(34892..35713)
                     /gene="yidA"
                     /locus_tag="PC366_002028"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HDF2577555.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMTLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNEAPGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIVDEP
                     ERLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCTNLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
BASE COUNT        14090 a         3850 c         6070 g        12062 t
ORIGIN      
        1 ttttaatgtg taaataacat tctacactat tgtaattaaa tatgtaaaaa gtaaaatatt
       61 taaatagata tattttaaaa tctaactttt aatattgtaa aaaaattaga aatttaacaa
      121 aaagtacaaa aattcacatt tttttcataa agtgtttgac taaaaaattc acatgttgta
      181 gaattaaggt agcaggagtt ttgagggagg tgtaaataat gataagaaaa ataccacaag
      241 cagaactaaa agtaatgaaa ttcatttgga aagtagatgt tacagtgaca tcaaaagatg
      301 ttattgaagc tatggaacaa aaatatggct ggaaacaaac tactacactg acacttttat
      361 ctaggctggt aaaaagagga ttcttagatg ctcaaaaaat agacagatat acacattaca
      421 caataagagt aaaacacaaa gattatttaa gttttgagac aaaggatttc ctaagtaata
      481 tacatgatga ctctttgaga agcttaattt cagcattaca tgatgatgaa aatataggta
      541 aagataagct agattttcta gaaagttatt ttgataactt aaaggatgaa taattatatg
      601 ctatatgttt ttgaaaatct tataaagaca actattgtat gtagtcttgg tatttgtcta
      661 ttattatttt tgaaaagata tttatttaag aagtttagta agagattcaa ttattatatt
      721 tggttgataa tagtctttag aatgttactt tttctattta attatacaat agtgtatgaa
      781 gtaaaagaac ccaaagaaaa tgcagtagga aataatatta cacaaattga tatttctaca
      841 gataataatc ttatgttgta tgtagcttat ttatggttag ttgtaactat agtcattgca
      901 gtttatacat ttataaagta tacaagattt aaaaatctag ttgttgatgt atcttatgat
      961 attgaagata atgatgtaaa ctgtatctac aaaaacttgt tgaaagaatt aaatataaaa
     1021 aagaaaattg aattaagagg ttctgatgaa ttgataagcc cagcaggcat gggattattt
     1081 aaatcttaca tattcttacc agactatcct tatagtaaag atgaactaac ttggattttg
     1141 aaacatgaat taatgcattt taaaaataaa gatattttaa taaagttttt agtgttatct
     1201 gttagaataa tatattggtt taatccactt gtttatgtaa tgagcaataa agtaaatcta
     1261 gattgtgaat tatgttgtga tgaaagtgtt ttgactgatt gttctttaaa ggataagaag
     1321 gagtatgcat tagcacttat aaagtcaatt aaacttagta agaattataa tagtggtatt
     1381 ttaacaacag agtttaataa gacaagtctg gaaaagagac ttgacagtat tgttaagaaa
     1441 aaaggtaaaa atggaatatt ggtgttattg attttgatta cattattttc agttacatat
     1501 tttaattttg aaagtattag ttttgataat tcaaattctt taaggaatat ggggatttta
     1561 caaaaatcag gagtagatct taaggaagaa gatgatatta gcatgagagt tataaattaa
     1621 tagattaatg tatgtaatga aaaggtatat tgtcgtatta ttaataaatt aggaggaatt
     1681 atgaaatgaa aaatttaaaa aaaattttaa taattacagg ttgtctaact ctaatatcta
     1741 ctagtttggt atttgcaaat actactactg atgtagatac atcaaaggat gatgattcaa
     1801 taataagttc atgtactata actggttatg aatttacata tgaaaacgca ccacaatctg
     1861 taaaatttga ttatgaaaaa aaatgtgaag cgctaaatat aaaaccatct aaaaatgata
     1921 taatttttgt taacaaagat tctatagatg caaatgatgt agaaaactat gttgagccaa
     1981 aagcatatat tattagatat aaaaaaggtt atgtttttga agttactgga cctaagagtt
     2041 atacattaaa tgtaagtaat actgtagtcg gatataatcg tgttgaatca ggtaatcctg
     2101 tgcatttagt tcaactttta tgtagaacct tagatggttc aagtattgat gatgatagtg
     2161 aatttggacc tgctacatat aatgcagtta agtcacttca aggaagactt ggattaacaa
     2221 gagatggaat tgttggaaga agtacttggg atgcagctgg aagacgtctt taaaaagaaa
     2281 gctattgcac agataatttt aaattgctga atctgtaaac atttacatgt attctttaaa
     2341 taaaaattta ttttttaagt gataattaaa tttttactaa tagggctatg gctttaaaaa
     2401 tcatagcctt attttgatat cttttccatt tttgcaaaag ctattaaccc tttaagaaaa
     2461 tttcttgttt ttttgaaaaa tttctttctt caaaataaat acttaaatga gctaaaattt
     2521 gagcacaatt tctaattttc tgagtccatt tttaagaaat atatatggtt gttaagtata
     2581 gtgatttgtg caaataatta tccaaagtaa aaatagattt caatttagta acttttctta
     2641 ataatctatt ctaacttccc attgaatttg tagtatatat cgatgtattt atttcttgag
     2701 agtacttaaa atatgttact aattcattcc aattgtttca ccaacctctt aatactattg
     2761 tatattgatt gtactatttt ttctctagtg atagctcact taatgctacc tcttctgtaa
     2821 ttgtagcata tctttcttta aatcttttac agattctttt ctatttttat atgatacata
     2881 atttaaagta tttttaattt gatgcacaac atatctttgt acttaagtat caggaaatat
     2941 cgctttaatt gcattagaaa attcaactag tctatctata gaagctgcta ttaatacatc
     3001 tttaattccc atgtttctag catctataag cacttttagc caatactttg aaatttcatt
     3061 ttctccaatc catattctta aaacctcttt tatgctacat atagctatat agactgtttt
     3121 gtttattatt cgacctcact tctaacttta taatgtatag catctataaa tacaattgaa
     3181 taaattatat taagaggtct aagttaccat ttatgagtta aaggaataac tttatcagta
     3241 gttttagtta ttagtgaatg agataatatc aattccataa gtacttttaa gatgacttaa
     3301 tatattttga gtagacatgc cttttgagta tattccaatc acttgatttt ttattcctaa
     3361 tatatcattt tctatcataa cctaaaagtt cattaagctc cgcttctaac atttaatgga
     3421 ttgtactttc aaataaatct tttagtatat cttgaatatc tgtaattgtt ttggcatcat
     3481 attcttcaat aaattttttt aatattttag tttttgttaa acataaaaag tgaacatctt
     3541 cctttgtata gtagtgatat tttaattatc acaacttttt agaagaatac aaactttatt
     3601 ttaaagacac tgaaaatggt gtttttatac ctttatttgc tatgtataat tttacttata
     3661 acataaactt atataaaaca gatattttaa taacacaaag gtacaattag gagattgtta
     3721 aaatttatta gatattactc tagtttattt aaaaaaaagt attataatat tccttgtgtg
     3781 aaaatatagg aatttttatt aaataatttt aatgtggaaa taacattctg cactattata
     3841 attaaatatg taaaaagcaa aatacttgaa caactatatt ttaaaatcta acttttagta
     3901 ttttaaaaaa ttagaaaatt aataaaaagt acaaaaatcc acattttttc ataaagcgtt
     3961 tgactaaaaa attcacatat tgtagactta aagtagcaag agttttgagg gaggtgtaaa
     4021 tgatgataag aaaaatacca caagcagaac taaaagtaat gaaatttatt tggaaagtag
     4081 atgctacagt gacatcaaaa gatgttattg aagttatgga acaaaaatat ggttggaaac
     4141 aaaccactac actaacactt ttatcgaggt tagtaaaaag aggattctta aatgctcaaa
     4201 aaatagacag atatacacat tacacagtaa tagtaaaaca caaagattat ttaagttttg
     4261 agacaaagga tttcctaagt aatatacatg atgattcttt gaaaagctta atttcagcat
     4321 tacatgatga tgaaaatata ggtaaagaca cgctagattt tttagaaagt tattttgata
     4381 atttaaagaa tgaataatta tatgctatat gtttttgaca atcttataaa gacaactatt
     4441 gtatgtagtt ttggtatttg tctattatta tttttgaaaa gatatttttt taagaggttt
     4501 agtaagagat ttaattatta tatttggttg gtaatagtct ttagaatgtt actttttcta
     4561 tttaattata cagtaatgta tgaagtaaaa gagcccaagg aaaatacagt aggaaataat
     4621 attacacaaa ttgatgtttc tatagataat gattttatgc tgtatttagt ttatttatgg
     4681 ttatttgtaa ctatagccat tgcagtttat acatttatgg aatacacaaa atttaaaaat
     4741 ctcgttgttg atgtatctta tgatattgaa gatcatgatg taaattgtat ctataaaaat
     4801 ttgttaaaag aattagacat aaaaaagaaa attgagttaa gaggttctga tgaattgata
     4861 agtccagcag gtatgggatt atttaaatct tacatattct taccagacta tacttatagt
     4921 aaagatgagt taacttggat tttgaaacat gaattaatgc attttaaaaa caaagatatt
     4981 ttaataaagt ttttagtttt gtctgttaaa ataatgtatt ggtttaatcc acttgtttat
     5041 ataatgagca ataaagtaaa tctagattgt gaattatgtt gtgatgaaag tgttttgact
     5101 gattgctctt taaaagataa gaaagcatat gcgttagcac ttataaagtc aattaaactt
     5161 agtaagaatt ataatagtgg tattttaaca actgaattta ataagacaaa tttggaaaag
     5221 agacttgata gtattattaa gaaaaaaggg aaaagtggaa tattgatgtt attgattttg
     5281 tttacattat tttcagttac atattttaat tttgaaagta ttagttttga taattcaaat
     5341 tatttaagaa atatagggat tttagaaaaa acaggcgcag atcttaagga agaagatgat
     5401 attagcatga gagttgtaaa ttaatagatt tttatagtat tataatttat taacaaatta
     5461 ggagaagttt tgaaattaaa aatctaaaaa aaatcttagt agtcacaggg agggtgactc
     5521 taatatctat tagtttagta tttgcaaata ctaataatga tgtaaatgta tgaaaaagta
     5581 atgaagagca aacaacaaat tcatttacaa taactggtta cgaatttatt tatgaaaatg
     5641 taccacaacc tataaaatct gattatgaaa aaaatgtaaa gaattaaata taaatccatc
     5701 taaagatgat acaatcttta ttaatgaaaa atttatagat tcatataata ttaatataga
     5761 tgattataat attgaaccaa aagcatttat tattagatat aaaaaagatt taaatcgttt
     5821 tgatgctact ggtcctataa gttatagcgt aaatataaat accactgtag taggatatgg
     5881 acatgtagaa aaagggaatc ctgtgcattt agtacaactt ttatgtcaac aaataaatgg
     5941 ttctgatatt gatccagata gtaaatttgg acctgctaca tataatcaag taaaaatact
     6001 tcaaggaaga cttggtgtaa caaaagatgg tgttgttgga aaagccactt ggcaagctgt
     6061 cggagagcgt tattagaaaa gaggttgtcg cactaagaaa tagggcgaca acttttttat
     6121 atagaatata ttaatcagta tcttagagtc tagaaatatt ttacaataaa ttccatataa
     6181 ctctaccatc tatatcctta acattttgac aaccagtcaa aatcatagtc tcacataact
     6241 cattcctaac cttctctata aaaaactcca caccatcaag accaccgcca aaagaagcag
     6301 taacaaaagg tcttcccatc aaaacagcat cagcacccaa tccaagcatc ttaactacat
     6361 caacaccagt cctaactcca ccatcaacaa gtattgttat ctttcccttt acagacttag
     6421 ctatatctgg aagtacctca caagtaccag gagtataatc aagtactctt ccaccatgat
     6481 ttgaaacaat aatggcacta gcaccagact ctacagccat caaagcatca tctacagtca
     6541 taattccttt tataataaaa ggtaatttag tagattcaac caattctcta atctcatcaa
     6601 ttgtcttagg agaaaaagga ttttcttgaa attgattatt aataagtcca caagcatcaa
     6661 ggtctacacc aactgcaaaa gcacctgctt cttcagacaa tctaattttt tctattatct
     6721 ttgaattatt ccaaggcttt ataaatacaa ttccatttcc actattatct ttcaacacat
     6781 ctaaattatc cagtaaaaaa gtatctacat tagtatcgcc aaccatagca taaattccag
     6841 aattagaaca acctctaaca acaggctcta tgtattcttt ttcggaaact ttaccaccca
     6901 tgttcaatag agtacctgat acaggtgcag cgaatatagg agaactcatt tttctaccaa
     6961 ataattctat ggatgtatct ggctttgaaa cattatgtat aactctcata tttatcttta
     7021 ttttttctag actttttcta ttttcaatga aagacgaacc acttccttta ccacccatac
     7081 caggaacatc tccagcacaa gctaatccat tacaaatttt acatacttta catgttccat
     7141 taaagttctc tctagctgat tttagtaagt cattgtaatt catacaaaat ctctcctttt
     7201 tataatatta aaattgagta ttactatatt gaaaatatct taattgtaaa tatagggatg
     7261 ttattatgat gagctaaact agataataca tattagatat tttttattgt tgtagatagt
     7321 taaattatat catattagat agtcaaattt tgaaaaaaaa ctaacttatt taagtataca
     7381 ttttgaaaaa attaaaaaag ctatatatag atttttaaag aaatctatat atagctttta
     7441 agtttatgtc aatctttttt tattaatgaa taaataatat agaatacaat atacaaaaaa
     7501 gtttcttaaa atgctaagat aatccccatt tacaaagcaa catcattata ctgtgtaaat
     7561 ttgaatcaac aatgttttca ccatatttca ccataaaatc ttctaattgt gtgtcaataa
     7621 atgaataata tccacttata ctatcgatgt atgcagtcat taagtgtata cattcatcac
     7681 ttttatcttt atacatatat atctccccct atatacaata tataaattta gatactaaat
     7741 cgtatcatat taaatagtta agtgtgtaac atctatgcag ttatatattt atatccttat
     7801 attaataact aaagtgagtt ttgacaatag attttgggaa actggatgtt caaagtgtaa
     7861 acttggattt taaaatcatt aattaagata gtgtatagga atatatgtat acataactta
     7921 attataaaga ttataaacaa ttacttttat taactttatt taagtggtag aataacttgg
     7981 agattaataa ttataaggag gatataatat gagtttatac aagtttatat atgatgataa
     8041 ggaatattta ttaaaagagg agaactgtag tgctttaata aatgatgaag aaaatccagt
     8101 tcaaggagta agtatttcaa aaataattga tatacttaat gaagcagaag aagttgattt
     8161 tgatgtagaa tattatcaag aagcatgtcc attatgttta gaaggagtaa aagaaaagaa
     8221 aaaattcttt ccttttttag aatatcactt ttatattttc agtaaagatg gagaatatgt
     8281 aataagcaat atatctgttg attataaagg actatctttt aataaactat caagggcaaa
     8341 taaagttgat aatagttata ttgtaagtgt gataatttgt gaaaattgtc aggattatat
     8401 agttcagata gaaaattgta tagtttagtg taaagtatgt cttaatttaa gagaaatttc
     8461 taaattgaga catcaatttt tttcaaaaat agtatggaaa attactaaat ttatgagata
     8521 atgtaagtcg gaggtgagtt acaatatata gtaaatattt ggaagagata gatgatacaa
     8581 ttttagattc aatgtttaaa ctaaccttga atgaaagatt attgactaat aacgattttg
     8641 ttgaaaataa aattggtgta gtaaagaatt taattgattg ctataaaact gaacaaaata
     8701 gtttaatgtt attaaaatca aattttttgc tagctttatt atatggtatt caagggttta
     8761 gtgaaaaaat gaaagagtat attttgattt cctgtaaata tattgataaa tgcttaccca
     8821 aagattataa atttttagca cgattttatt cacaaatagc tattttaagt ttaaaaaatg
     8881 aagatgtaaa taaggcaaat ttatatatgg ataaatttaa tcttatttgt gatgaaaata
     8941 attttctaat tgaagaaatt atttttaaat cacaacttat ttacattaag gcaagtaagt
     9001 gtatagaatc ttctgtaata attaaagaaa tagaaacatt gtatataaag ataaaagaaa
     9061 ttaacgattt taactgtaaa aaaatatatt tttttattat tggtaaaata tattttttgt
     9121 ttttggatga tgctctaatt gctaaagtaa attttttaaa agcaagaaaa tatgcagatt
     9181 tactaaagga tatgcaagta tcttcactat gtaatataaa gataggtgag tgtgaatgtt
     9241 catttgaaaa ttatgaatgt tccatagaat atttaaatga agtaataagc aataaaaagt
     9301 atagaaatgt aaatataatt caaaaatata gagcatcaaa caacataact aaaatattaa
     9361 taaagactag aaattatcct gtagcaataa ataatttagc aaaatctgaa gtatatctag
     9421 aaaaaattaa aaatcagagc ttaaaagaag tagagaagtt tgatttattt ataagtttag
     9481 ctatgtatta tgcaaaaagt aatgaaaaat cttttgaaca atcaatatgc tatttagata
     9541 gagctaaaaa catcttaaat atgataaaaa atatagaaga atatacaata tatgatttag
     9601 aaataattta tcatcaggca aagatatatt atatctttgg atattatgac aatgccttaa
     9661 acacaaataa aaaactcctt gaaaaatcta aaaatgctaa aaattataat tatgtgaagt
     9721 tagcatacaa gaatatatat ttgtgttttg aaaagattca aaattatgaa atgagtatga
     9781 aatactttaa aatgtattat gagttaaaaa tgatgtatat aaaagctcga aatagaaatt
     9841 atatagattc cttaaattat agacatgagt atatagaaac agaaataaat aacatgagaa
     9901 aagtaaaact tgatttagat aaaaaaaaat atgttgacca tttgacaagt gcatataata
     9961 gaactttttt gaacgatttt ttagaaaaac aagaagttag tgaatattgc acagcattta
    10021 tgatagatgt agattacttt aaagaataca atgatactta tggacactat aatggagata
    10081 ttgctcttaa aaatataact ataataataa aaaaatatct aaaaaaagac atgtttatga
    10141 taaggtatgg tggagaagaa tttctgatat tatctgtatg taaagattat aaaaaaagca
    10201 aaatatttgg aagaaaatta tgtaggattg taaagaaatt tttaaacaat aatttgacag
    10261 ttagtattgg cattgataca tgtaaaaata gtagtataga tataagagaa ataattgaaa
    10321 atgctgataa agctttatat aaagcaaagg aaagtggtag aaatagatgt ttgcattatc
    10381 atgattttaa gaatttttaa ctgttgaaat aggattggtg atttacttga aaaggagttt
    10441 aatagaagat ttaaagagaa atataaacaa gatagaatac gatatgttga ctaaattcta
    10501 tctaaatttg acagatttaa actacatctt ggattatcac aaagaccttt taaatacaaa
    10561 actagaagat aatagtagag tctatacttt atatttaatt agccttataa actatataaa
    10621 aaaagataga gaagcatcat acaactattt gatagagtca ttaaagtata ttaaaaaatt
    10681 gtcattaaaa gaagattcag atataatatc taaaatttat atttatctta ctttatcagc
    10741 tatttctata agaaaatatg ataaggcaaa taatttttat ttctcagcaa aaaaagttat
    10801 aagacaaaat catttaaatg agttgctagt cttgttaaat atgagtttat gtgtagaaat
    10861 aagtgcttta tatcagacca aaacggatgt aatagcttta gtagaagaag tgtctttttt
    10921 taaaacttta aaaaataaag ctcttgtaag tagggcaaat tatatatttg ggagagttta
    10981 tctatattta tttaataact ttataaaaag tatggagtac ctaattgaat gtctaaaact
    11041 ggctcaagaa aataatttat attctataga ggctttttgt aaatgtataa taagtttgtg
    11101 ttatttagag agtggaaata atgtagaagc tataaaatac ataaataatg tattagatgt
    11161 tgcgcacagt aagaactcaa tatcagtaac tgaaagagtg tctataaaga tagaccttat
    11221 atgggcatat ttaaaagaag atatgaataa agaagcagaa gttattttat taaagactat
    11281 aaaattaatg aaagttgttg aaggtgtata taaggattat ttatattcat ttatattttt
    11341 atattcagct gaaattgagt taaggaaaga taattgtagt tttgaaaagg taaataccta
    11401 tttaatttta tcaaaaaata tatataaaag ttttggcgat gtttttatat ataattctaa
    11461 actagattac atatataagt tgtatggaga tttatatata aaatttggta atatagatga
    11521 aggtataagt tgttatataa aaggtttaaa tttagttaaa aagagttcat tgaatcttag
    11581 aaaaatatct atattttatg ggctaatagc aaatggatat gagctaaaaa aagattttaa
    11641 actggcaata gaatattata aaagtatgga ttggtattct gataggtggg aaaaaaataa
    11701 ttcctataaa acatctcaag caattcacaa acaatatgaa ctcagacaaa aacaagagag
    11761 tttaagatta ctagtggatg ataataagaa attagaaaat gatattttaa aagatggact
    11821 tactaaacta tataatagaa gatatttgga acagcagttg gatttattta atggaaccag
    11881 agacaaaaat atggttgcaa tactagtcga tatagattgt tttaaaagtt ataatgataa
    11941 ttatggtcat ctagcaggag ataaagttat agttaaggta actgatatta taagaagtgt
    12001 atttatagat attaccgaac atataatcag atatggggga gaagaaattt taatactagt
    12061 agattctata gaatcaatcg gtgttgaaga gattgataat atagaattat atattaaaag
    12121 agttttcaaa cttcttgaat ttgagggtat tgaacatata tattctaaaa taaaaaacta
    12181 tataactata agtgctggag taagtataaa aagatgtcgt agtagaaaag atgttgaaat
    12241 attaattgaa gatgcagata agaacctata taaatcaaaa aaagcaggta gaaatcaata
    12301 cattataatt taaaattgag gtgattttgt tgcgaaaaaa aataggaatt atagcctctg
    12361 atattgaatt aaaagaaaga atagaagaat tatatagaga agatgtagaa aatggaacta
    12421 taataatcga catacttaac ctagacttaa tggaaaatca aggtcgtata cttgttgaaa
    12481 aaggtgccca agctataatt ggtagaggtg gaggttatag tttagtaata gatacagtaa
    12541 atgtacctgt tataccaatg aatatgaagt caactgacct tttaagagca atagaaatag
    12601 caaagaaata ttctaaaaaa gtagtattga ttcttggaga caatgaagtt tcttttgact
    12661 atgttggctg gagaaatgtc ataagtactg aaataactga agaatggttt gaatctaagt
    12721 atgagataag aagtaaagtt gtaaaatata tagaccaaaa agatgaagtt gtaatcgtag
    12781 gaggaggttt ggcatgttct tttgcaaggc aatatggaat tgatagtgta tttgcaactg
    12841 ctagtgatga atctataaga gaagctgtag aatattgtaa aaaattattg gatacattag
    12901 gtgaagaaaa gtttaataat gaagtgttac gaaatatact tgatggtata aaagatggag
    12961 taattgctat agatagtaat ggtagtataa ttttgtacaa tgaaagtgca aaaaacatgc
    13021 ttaaagtaga gagaaaatgt gcacttaata aatacatctt agatgtattt cctaaaatgg
    13081 agtggatgtt agattgttta catgaaaaag aggatgtaga agatagaaag ataagaaata
    13141 taaataatct aattgttaat actaggacaa cattaataaa agttgataat agtacttatg
    13201 gagttttagg aataatacaa gatataacca agctacaaaa cttagaaaga aaaataagat
    13261 ttgacttgaa tcaaaaaggt ctctatgcta gatatacttt tgatgatttt ttatttaaag
    13321 ataaattaac tagagaattt attgaagaag ctaaaaaaat tggaaaaagt gattatacaa
    13381 ctttacttta tggagaaagt gggtctggta aagaaattat agctcatagt atacacaata
    13441 taagtaaaag aaaagatagg ccttttgttg ctataaattg tgctactata gcagaaaatt
    13501 tacttgaaag tgaacttttt ggctatgaag aaggtgcatt tactggtgct agaaagggtg
    13561 gaaaaagagg actatttgaa cttgctcatg gagggactct ttttttagat gaaataaata
    13621 gtctatcctt taatattcag acaaaactat taagagtaat agaggaacgt caaataatga
    13681 gaattggttc tgattatata atacctctgg atataaggat tatagcagca acgaacgaat
    13741 ctttaaccga aaaaatagtt atgggtacat ttagagcaga cttattttat agattgagta
    13801 gtttagagat aaatatacct cctttaagag acagaagaga agatataata cctttgttta
    13861 acaattttgt aaatgaagta ttaaaggatg atggtctcaa tggaataaac agtatagatg
    13921 aaaattttgt tttgactaaa gatgaaatgg ataagctata taattatagc tggcctggaa
    13981 atgtaagaga gttaaagaca atagctcaaa aatatgttgt gacaggtaaa attaaattga
    14041 gacaagatag agattttaaa actaaaaaat tacttcctaa ctctgaagta gacaaattta
    14101 attctgaaac gacagcaagt gtagaagtcc aagatgaatc tataaatata agtaagataa
    14161 atgatggtaa gataagtata gatataaaag aagtaaataa gtatgttgaa gaaaaaataa
    14221 taagtatgct ttttgctcag ggactttcta aaaatgaagt tgcacaagtt cttggaataa
    14281 gcaggacatc tttatggaag aaatacaata aaaatattta aatataatta catataaatt
    14341 attttgaagt aatgttaatt ttttaaaaca agtgttaaga aaaattaaca ttactttttt
    14401 gtaaattttt atttttttag acaggcatat atatttataa gaaaaatagt taaaacactt
    14461 aatttaataa tgaaaaaaat aataattcta aacaaaatca attttacata aagtgggatt
    14521 tattggcata gtaattgctt aatatataat gtaagagtaa atacaatttt aggggtgatg
    14581 gtatgagtca aagtatggtt ggtaagcatg caatgtggcc aaaagaaaat gatgttatat
    14641 ttagcatatc tggtagagct caagcagcag agaaggcttt tggtatggat aatgtaataa
    14701 atgcaacaat aggcgctcta atggatgatt caggaaaatt aataacaatg aaaactgtat
    14761 atgaagaata taaagcatta gataactgtg agataggtgc atatgcagct cttgaaggtc
    14821 aaccagacta cttagaagca gttaaaaaag tatttttcag agattactta ccagaaggac
    14881 atataagagt attagcttca ccaggaggaa gtggtgcaat aaaattagct gtatggaact
    14941 atactaatga aggagatgag gtattaacat ctgattggtt ttggagtcca tatgtaagta
    15001 tagctgaaga ggctaataga aaagtagtta attaccaact ttttgatgaa aatagaaggt
    15061 ttaattttga gtcgttcaaa gaaaaatttg taaatatagc agaaaaacaa ggtagagtct
    15121 ttacaattat aaacacacca gcgcataatc caactggata tagtgttgca gatgatgagt
    15181 gggataaaat attagactta tcaaaagaag tcgcaaaaga taaagacaaa aagataatat
    15241 ttttcgtaga ttcagcatat attgactttg caggtgatga tgatgtatgt agaaagtttt
    15301 ttaagaaatt ttctaatttg cctgaaaacg ttctcgtatt ggttggattc agtatgtcaa
    15361 aaggatttac agcttatggt atgagaatgg gggctataat ttgtatatct tcaagtgaag
    15421 atgtagctga agagttccat tactcatgtg ttcattcatg tagagcaaat tggtcaaatt
    15481 gtaatagaag tgccatggca gtattatcta acattgtaaa tgaccctaaa aaattcaaag
    15541 aatatgagga tgaaaaagaa atatacaaaa acatgcttac tagaagagca gatgtatttg
    15601 tagaagaagc tgaaagagta ggattagaaa ttcttccata tatagcaggt ttctttgtaa
    15661 gtataccatg tgataatcca aaagaagtat gtgaagaatt gactaaacat aatttatttg
    15721 cagttccatt aaaaatgggc ttaagatttg cagtttgtgc agtttctgaa gataaatgta
    15781 agaaagcacc aagtattata aaagaagcac ttgaaagttt agaagtaaaa ataaataatt
    15841 aatttcattg aacaaattgg gtggactatg aatttaataa ttgtagatgg agggaatttt
    15901 atatgaaaca attgatgaca ggtaatgaag caattgcacg tggagcctat gaggctggtg
    15961 ttaaatatgc atctgcatat ccagggactc caagtacaga aatattagaa aatatagcaa
    16021 catataaaga tgcaatagtt gcagagtggg ctccaaacga aaaggtagca cttgaggctg
    16081 ctataggggg ttcaattgca ggagcaagaa caatggcttc tatgaaacat gttggtttga
    16141 atgttgcagc tgatccaata tttacttatg catatacagg ggtaaatggt ggtatggtac
    16201 ttattacagc agatgagccg ggaatgcatt catctcaaaa tgagcaagat aataggatgt
    16261 atgcaaaatt tgcaaagata cctttatttg aaccatcaac tagtcaagaa gctaaagata
    16321 tgataaaaga agcttttgaa gttagtgaaa aatacgatac accagtttta tatagagtta
    16381 caacaagact ttgtcattca aaaggattag tggagtgcta tgatagagaa gaagttgaaa
    16441 ttaaagagta tgttaaaaat gctaagaaaa tggtaactgt tccagcaaat gctcaaataa
    16501 gaaggggcgt tgttgaagaa agaatggaaa tccttaaaaa attctcaaat gaaactgatt
    16561 taaactacta tgaaatgaat gatacaaaaa taggtgttat agcttctggt atgtgttgta
    16621 attttgccaa agaagttttt ggaaaaaatg catcatatat gaaactagga tttacaaatc
    16681 cattacctta tgaaaaaata aaagaatttg cagaaaaagt tgataaaata tatgttatag
    16741 aagaaaatga cccatttata gaagaacaaa taaaagcata tggaatagat tgtattggaa
    16801 aagatgtaat accaccatat ggagaaatga caccagatgt tttaagaaaa gctatatttg
    16861 gaaaaacaaa tgatactata gaatacaaat ctgaattagt aacaccaaga ccaccaagtt
    16921 tctgtgcagg atgtccacat agaggattct tctatgaact tggaaagaga aaaaatttaa
    16981 tagttggtgg agatataggt tgttatactc ttggatttgc tcctccatat aatggaatag
    17041 attatgttgt ttgtatgggt tctgcttttg gaactgcaca tggagctcaa aaagttctta
    17101 atatgaagga tgataatgaa aaaagattgg taggtgtact tggagactca acattcttcc
    17161 atacaggaat aaatggactt ttagatgttg tttacaatag aggtaattct atttcggtta
    17221 tattagataa tagaataact ggaatgacag gtcaccaaga aaacccaggt tcagggtata
    17281 ctttacaagg tgctaaaact aaagaagttg atatagaagg attagttaaa gcttgtggaa
    17341 tagaacatgt aagagttata aaccctaaca atttaaaaga agtaaatgaa gcactagatt
    17401 gggctttagc tatagaagat gaaccatcag taataataac aagatggcca tgtgtactta
    17461 aaaaattctc taaagaagat atagaagaat ttaataatcc atttaagact aagtgtaaag
    17521 ttgaccatga taaatgtata ggatgtaaat tatgtttgaa aactggatgt ccagctctat
    17581 catttgataa agagaataag ttatcaaata tagatagaaa tcagtgtgta ggatgtggag
    17641 tatgtgcaca agtttgtcca aaacaagcaa tagttaagga ggaaaaataa tatgactaag
    17701 agtatacttt tggtaggtgt aggaggtcaa ggaactatac ttgctagtaa attattaact
    17761 atgggattga tggaagctgg atatgatgta aagatgagtg aaatacatgg aatgagtcaa
    17821 agaggaggtt cagtttcctc acaagttaga tatggagatt gtgttcattc tccagttata
    17881 gaaattggtg gagcagatat attagtatct tttgaaaaaa tggaagcttt aagatggttc
    17941 aattatttaa aaccagaagg aaaagcttta gtaaataatc ataggataga ttctatgact
    18001 gttttaatcg gaggagctga atatcaagaa agtgatatag atgcagagtt aagtagatta
    18061 aatgcaaaag ttataaatgc agctgataaa gctgaagaac taggaaattc aaaaataatg
    18121 aatgttattt tattaggatg tctagttaaa tctatgcaat tagagtctat tgattgggaa
    18181 aaaattataa gtgaaaatgt taaaccaaaa tttgttgaat taaacataaa agctttccat
    18241 gaaggtatgg aaatggttag caaatagttt ataatagata taaatagact atagaaatta
    18301 aggtgaaagg aagaaaatta tgacttacag aatattagcc ataaatccag gttctacttc
    18361 tacaaaaata gcagtatatg atggagaaga acaaattctt gtgaagacga tagaccatcc
    18421 agctgaagag attgcaaaat ataatactat acaagaccag tttgaaatgc gtaaggaagc
    18481 agttttgaat attcttaaag aaaatagtat agacttaaaa tctcttagtg caatagtagg
    18541 aagaggtgga gttttaccac cagtaaaatc aggagcatat ctagtaaatg aagaaatgat
    18601 tgatgtacta agacatagac cagtacttga acacgcttcc aatttaggtg ctgttgtggc
    18661 acatgcaata tcagaacctc ttggaatcaa ctcatatatt tatgattctg ttgcagtaga
    18721 tgagcttata gatgtagcga gaatatctgg actttgtgga atggatagat caagtgcagg
    18781 gcatgcatta aatactagag caatggcttt aaaatatgct aaggataaag gaaaagatta
    18841 taagagctta aacttaatag tagctcacat tggtggagga gtaagtattt atcttcatga
    18901 aaaaggaaga atggttgata tgctatctga tgatgaagga ccattttctc cagaaaggtc
    18961 aggaagagta cctgctacaa aattagtggc tgcctgttat tcaggtcaat attcagaaag
    19021 agaaatgact aaaaagataa gaggtaaagg tggtatagtt tcatacctaa atactgtaga
    19081 tgctagagaa gttgaaaaaa tgatagcaga aggaaatgaa gaagcaaaaa ttatttatga
    19141 agcaatggct tatcagttag caaaaggtat tggagagtta gcaactgtag tagatggaaa
    19201 ggtagatgct ataattataa caggtggaat tgcatattct gaaatgttta cttcaatggt
    19261 taaaaagaaa gttgagttta tagcaccagt agaaattatg gcaggagaaa atgagttgga
    19321 atcacttgct tttggaactt taagagtact aaatggagaa gaagaagcta gaatttatag
    19381 tgaaaattaa taagaaaaat taaaaatgtt tatatactaa aaaagtggta tatccgtttt
    19441 ttatacacga aagcttagag tataggtgaa aatgtataaa atttggattg ccacttttta
    19501 taattaaaat tttatcttaa tctaataaat aattctgtaa aatttcgtat ttatatatat
    19561 attttattgg tatttattgt tattattatt atgaggagtg atttttgatg ggaaaaataa
    19621 gtttaaaaag tatgataaga ttattttcag gtttttttat atttgcaatt tcttctgtgc
    19681 ttatgattaa tgcacatgta ggtcttatgc cttgggatgt acttcaccaa ggtttatcta
    19741 taaagctagg cataactata ggtcaggctt ctataatggt aggagttgta attgttatat
    19801 tggatgcagt ttttggtgaa aatataggat ggggtacttt actcaacatg acatttatag
    19861 gaatttttat tgatttagta atattttctg gagtgatacc tcatgcaagc aacacttata
    19921 taggtgtgtt tatggttgtt ataggaatta ttttggcagc tatagcaagt tttctatact
    19981 taggtgtttg tttaggaagt ggaccgagag atgggcttat gattgctctt cagaaaaaaa
    20041 ctaataaatc tgtacgtctt gttagaacaa ttcttgaaat actagcatta gttgttgggt
    20101 ggttattagg aggttctgta ggtattggta cgcttgtaag tgctttaggt ttaggatatg
    20161 tattacaaat agtgtttaga atatttaaat ttgacacaaa gttgctgaaa catagattta
    20221 ttatagatga tataagagaa tggaaggaaa agagaagcaa tgaacataaa tgtaaatcaa
    20281 gtattgtaat aaaaaatgag cagaattaat tatgctaaaa tatatttgta gtttatctaa
    20341 tttatagtaa agtcaggaga ttttgaaatg gaattatggg atttatataa tgctgatgga
    20401 attaaaacag gaaatgttat aaaaagaggt aattctattg aagaaggtta ttaccatttg
    20461 gcagttgaag tgtggatttt aaatagtaac tctcaaattt taattcagaa aaggtctaaa
    20521 agtaaaaaga cattgccaaa tatgtgggga atgacaactg gatgtattgt ttctggggaa
    20581 gatagtttag aaggagcaat tcgcgaagca aaggaagaaa tagggataga tataactaaa
    20641 gatgagatga aagtttttag aagtatgatt catgaagata ctctttggga tgtatactta
    20701 gttaaaaaag aatatgatat atccaaagct attttacagg aggaagaagt aagtgatata
    20761 aagtgggtaa gcacagatga aataagacaa ttactaaaag agggtttgtt ttttgaatat
    20821 ccagagatgt acgaattgct atatgagata gataataata aattaaatat atgatgtaga
    20881 gcagatttca gtataagtaa gattatttaa aatgtatctt ctctaaattt taatattgtt
    20941 ttatgaaaat taataagtta tttttagtat ttttctactt gttttttgag attaaaataa
    21001 aaagggcagt cattataaag tcataaaaat ttggggagga tttaaactat ggaagataac
    21061 aaaggattgg cacgtgatag ttcaaaatat aaaattgttt ctatatctgt cgtagtaatt
    21121 attctaatta cattttggta tatgttaaat atggtgcttt taacatttat tatgactttt
    21181 attttctata acttgcttgt agccacaaga aaacgaatta agaagttttc ttctttaaat
    21241 attccagatt cattgataat tatagtgtta tatgcactat ttgctatatt gttagtattg
    21301 attagctatg cagttgtacc aataattata gttcaactta cagagctgag tagggttttt
    21361 agtgattttg atgtaaatca atttgctcaa tctttaggac caaaattgta tcctattgtc
    21421 tcaaagctgg attttaataa atatatttca caagcagggc tacttatagc atcaacagca
    21481 acaaaagttg gaagttttgg agtaaatata ttattggcat ttttactgag tttactcctt
    21541 ttacttgaaa aaaatgaaat taaaaatttt ggagataaac tttctgatag taagatttct
    21601 tttatttata attcgcttgt attttttgga aagagctttg ttaaaaattt tggtgaagta
    21661 atgaaagtac aagttatgat tgcctttata aattctgttg tttctatgat tttcttaggt
    21721 ttcatgggat tccctcaaat atgggcttta ggatttatga tttttgtgtt gggtcttatt
    21781 ccagtagcag gagttatagt gtctttgatt ccattaactg taatagcatt taatacagga
    21841 ggaataacaa aggtttttgg agttttactt atgatttgta tagtgcatgc agtagaaaca
    21901 tacatattaa accctaagtt gatgtcgaat agaactaaac ttccagtttg ttttgttttt
    21961 attattttac ttgtaggaga acattattta ggtgtatggg gattactaat tggagttcca
    22021 atatttatgt tccttatgga tattctgggt gttaaattta cttctaggta atatattaaa
    22081 ataataattt atttttatat ataaattatg aattgtttta aaaaagaacc tataaataga
    22141 catcattaat aaagacatct atttgatagg ttcaattttg ctttgtataa atactataga
    22201 attaaataaa aagaaattta tttcatttca aaagtttcac aacttgcatt tctttcattt
    22261 atatgaactt tttcagcttt gcaaagttca tttttattgt atttacattt tacagcttca
    22321 caatgaatgt tatctgtatc aacttggtta gtttcattag aacgactagt tataccagat
    22381 gtatatttgt cttcaaaaga agcacaataa gtattttctg tagtagttgc ttgcattcca
    22441 tctactttta tactaccagc ataacaatat ccactagtat tataagcaca attagtagca
    22501 gcacaattta aattattatt tttcataaat aacctcctaa gttttattta aacttattat
    22561 gtgaagttat ctaaatttta tacacttatt tacaattaca tttatcacat ttaacaacta
    22621 catctttgga agtttccctt cctaaatttt tattaacatg atacacatca acattttcag
    22681 ttgatccaca tatagaacat ttaaaattgt tttctagtag ggttctttct ttaaataact
    22741 tccaatacat agaattgatg taatcattat aatttacctt gaggcatgtc tcaagaaagt
    22801 ttatgtatag attgtctaaa tctcctgtat ttaattctgt atattctggt tcaaaatatt
    22861 cacaacatcc tctaaaatca ggctttgtat ctgaaataac acatctaata tcatatctat
    22921 agtctaggct aggcccctta aatgaaagat gtgtgcaaaa agaacaagat gtttctggta
    22981 gatttttttc aagttcatgt aatttattat tcataagtat tcctccaaaa aatttatttt
    23041 aagtatataa atgaatagat tattttaaaa cttttattta tttatattag agatttagga
    23101 taaatattcc aataaggagt aaatacttaa gtatttatta ctgtattaaa taaaaaagag
    23161 gcaaatctaa cttgagattg cctacttttt tatcattttt taataaaatt tattctaagt
    23221 attattttat ttagatttag tcagccaatt tagtatccgc tttgcttttt aactttctac
    23281 cagagcgtac agttaaaata gcatataata cagtaaatat ggcagctaaa acatatgata
    23341 tatttatgtt taagttaaat ccaatttgag cattaaatat ataactgaat ataacaaaag
    23401 aataaaacat accaggaatt aagcttataa tataattctt ttcttttatt ataaggtaaa
    23461 ctgtaatcat tgcaaatgca aatatggcaa tagtttgatt actccaagag aagtatctcc
    23521 acaatatatt aaatccagaa gcactaagct ttgcaaatat aagaatggct atgacaggaa
    23581 taaatataca gattgacaat ataacacgat gtttcttttc cttttggtca taatgaaagt
    23641 aatctgcaag cattaatctt aaagatctta aagctgtatc tccagaagtt attggtaaaa
    23701 caattacacc tattatagct atgataccac caatagaacc aagtaaatct cttgcaacca
    23761 aacctattac atcaggagaa cctactaatt ccttaggtat tcctttattg taaataccca
    23821 tagcagctgc agcccaaatc attgcaatta aaccttctaa aatcatcata ttataaaaag
    23881 tagtttttcc ttctttttca tttgaaactg atcttgctat aagagtagct tgagttgagt
    23941 ggaatccaga aacgatacca caagcaactg taacaaagaa tgtaggaata agaggaatac
    24001 catcaggatg aatacctttc caatttgcaa gacttaaatt agctaaatca taaccttgtg
    24061 taaagattcc aattccaaca ccagcagcag ataaaagtag aatagctcca aatattggat
    24121 atacctttcc tatgatttta tcaattggaa agagtgttgc acacaagtaa tatagaaaga
    24181 taagtccata aactatccag acaactggat tatttatagt cgatttcata tttaaaattt
    24241 gagtaacaac taaatcccca ggtgtataaa taaaaactgc accaactaaa agcattaaaa
    24301 gacaaaggaa tatattatag acttgaaata ctttattacc taaaaatcta ctgataagag
    24361 aaggcatttg tgctcctttt tctcttatac taatcattcc actcatatag tcatgcaaag
    24421 ctcctccaaa tacacagcca ataggtatta gtatgaatgc tattggacca aacaatatac
    24481 cttggatagg tcctagaatt ggtcctgtac cagctatatt aagcaactca attagactat
    24541 ttttccattt tttcattggg acatagtcta ctccatcact ttgagcaagt gcaggtgttt
    24601 ttctgtcatc tgggccaaat actttttcac aataagcacc gtataaagca cctcctatta
    24661 gtaatatagc caagccgatt aagaatgttg tcataatatc accccattta taaaattttt
    24721 tggtctttgt atacatatta tctaaatgtg tagatttata ttgaatttaa ttctggacaa
    24781 cctacaaatt ctataaagta ttacaactaa tataatttca gaaataaata catatacata
    24841 accatgtact tagtatacag gtatttggta atattttcaa tgttatagca ataaagaata
    24901 taaacaaaat tctgataata ttttacaaaa aaattaaaaa atataaaaat tagtttaaat
    24961 agatggagaa aaaaggaaaa tcaattgaga atataaatgt ctatatctta acaatattaa
    25021 gaggtttaaa attcttgaag aaagaatagt caagtgatat aatgggttta caggtgtata
    25081 tacactagta catatagaaa gcggtgcaat tatggataaa gatttaacat atcaaatcaa
    25141 agagctaaag aaagaaaaaa atgcaataat acttgcccat ttttatcaac caccagaaat
    25201 acaagaatta gcagatgcag ttggtgactc atattattta agtgagattg ctagagattg
    25261 taaagaagaa gtggttgtat tttgtggagt aaggtttatg ggagaaagtg ctaagctatt
    25321 atcacctgaa aaaactgtat tgatgccagt aagtaacgct gggtgtgcta tggcagatat
    25381 ggtagatgaa gaaggcgtga taaaattaaa acaacagtat ccaaatgctt tggttgtatg
    25441 ttatataaac tctacagcta aagttaaggc acattgtgat gtttctgtta catcttctag
    25501 tgcaattaaa atactagaaa acatagataa taaagaaatt atattccttc cagataaaaa
    25561 tttaggagga tatattgcag aacaatttcc agataaaaac tttatatttt gggacggata
    25621 ttgtaaatac cataacaata taagagctga agaaataatt gaattaaaag ataagtataa
    25681 aaatgcagaa gtattagtac atccagaatg taaaaaagaa ataagagatt taggagatta
    25741 tgtaggtagt acatccggaa taataaaata tgctactaat agtaaaaaca aagactttat
    25801 aatagcaact gaagaaggta tattacatga attaaagaaa aataatccta ataaaaactt
    25861 ttatattcct ggtggaaaaa tactatgtac agatatgaaa aagacaacat tagaaaattt
    25921 atatagtaca cttaaaaata tggaaaatga agttattgta gaagatgaaa tcatggaaaa
    25981 ggctttaaat tcactgctta acatgcacaa attagcagaa ggatagaggg atagacttat
    26041 gaatttagaa caagatgttt taatagttgg aagtggagtt tcaggattat actgtgcatt
    26101 aaatttagat aaaagtttaa atgtgctagt agtatcgaaa tcaacaattg aaaacaacaa
    26161 tacatatctt gcacaaggtg gaatttcaac tgctagaaat attgatgata tagaatcctt
    26221 tgtagaagat acaatgaagg ctgggcagta taaaaataga gttgaagcag ttcaagtact
    26281 tgcagatgaa tctatagaaa atgtagggca gatagtagaa tatggtatgc ctttagacaa
    26341 agaaaatgga gagatagatt acacaagaga aggagcacat agtgtaaatc gaatagttca
    26401 tagtaaggat aatactggag aagttgtttt taaaacttta ttaaaagaag ctaaaactag
    26461 agaaaatata actcttatag aagatgcata tcttttagat atattaaaag atggcaataa
    26521 atgtatagga gctagaattt ttaaatctaa aaaagagatt catgtttttt caaaaatagt
    26581 agttttagct acaggtggaa ttggtgggct ttttaaaaat tctactaatc aaagacatct
    26641 tacaggtgat ggaattgcaa tagctttaag aaataatata aaaatagaaa atttagaata
    26701 tattcaaata catcctacag ccttttatga agaaaataat gaaggtagga gaatgcttat
    26761 atctgaatca ttaagaggag agggagctaa acttttaaat aaaaataaag aaagatttgt
    26821 ggatgaactt cttcctagag atgtagtttc aaaagctatt tttgagcaaa tggaaaaaga
    26881 taaattacct tatgtgtatt tagatgcaac acatttagat agtgaatatt taattaatag
    26941 attttctttt atttataatg aatgtttagc tagaggaaca gatataacga aagaatgtat
    27001 aaaggtatct cctgcacaac attattttat gggcgggata catgtagatt tggattcaaa
    27061 aacatctatg gaaaatttat atgcagttgg tgaaattagt tgtacaggtg ttcatggagc
    27121 caatagattg gcaagtaatt cattacttga agggcttgta ttttcaaaaa gagcagctaa
    27181 aaatataaac tcagttatag ataatgtaaa agttaagttt atagatgtac cagatatgga
    27241 tatagatata gaacaggtaa aaaaagaaaa taaaatatta gtcataaaag aaattgaaag
    27301 aacaagtgag gattttggcg atgaattatt tgattattga tagaatgata caggatgctt
    27361 tgatagaaga tgttccaagt gaagatataa caactaattc tattgtggat gaaaattcta
    27421 aatctactgt agatttaatt tgcaaacaag atggtataat agctggctta ggtgtattta
    27481 agagagtttt tgagatactt ggtgatgtag atgtaaaatt atataaaaat gatggtgata
    27541 gagtaaagaa tcgtgaaaag atagctgtat taacaggtag tactagaaac ttacttgtag
    27601 gagagcgtgt agcattgaat tatttacaga gaatgagtgg tatagctact attacaagta
    27661 ggtatgttga aaagcttgaa ggtacaaata caaaattatt agatagtaga aaaacgatac
    27721 ctaatcttag aatattagat aagtattctg ttaaagtagg tggaggatgc aatcatagat
    27781 ttaatttatc tgatggaata ttgcttaaag acaaccatat tggggctgct ggtagtgtta
    27841 agaaggcagt tgaattagct agaaaaaata cttcttttgt tagaaagata gaagtggaag
    27901 tggaaacttt agacatggta aaagaagcaa tagaagctaa tgcagatata ataatgttgg
    27961 ataatatgag tttggaaatg gcaaaacaag cagtagatat tataaatgga agagccattg
    28021 tagaattttc cggaaatgta aatttagata ctatagaaga tataggaaaa attggtgtgg
    28081 atgttgtttc tgtaggagcg cttacacatt ctgttaaagc tctcgatata agtatgaaga
    28141 atttgagaaa tatataagtt ttatattgaa ataaacttaa ttaaaataga ctccttaaat
    28201 ttgttttata aatttaagga gtctattttt tattcattaa aattaataaa aatataaaaa
    28261 aatcaatcaa taatttaata aaaatagata aatactatat acacttttaa taatatagct
    28321 aatatctatt ttacagataa ataagaataa acttataata taattgtatc tgtaaaattt
    28381 tgtaaaatat aaaaagtata gggggaataa aaatgaaagt agcttatatt tttagtagta
    28441 ctaatacaca taaaattcta gacaaaatga taataccaca acttgaacaa ggaactcatg
    28501 gagtagacgt tctagggatg tttttcttta tggataatac cttattttta tctaaaggta
    28561 atccagtagg cgagagacta agtaaattac atgaaaaaac tgatatgata ataatggctt
    28621 gtgaccaatg tgctatagaa agaggtatag agaataattt ggttgatgga gctacaattg
    28681 gatgtttccc aaacctatat gcttgtttag gcagtgcagg tgtggaccaa gttataacgt
    28741 tataaattag tataggatac aatccataga aaaatttatt ttctgtggat tattttaagt
    28801 aaaagataaa ttgtttaaag taggggatga acaaatgtct aaaattttag ttgaatttat
    28861 aaacacttga ccatcttgtg atgaacatgg agtgtttata aaaaaaatgt cagaaaagta
    28921 tgctgataaa ttggaaataa aattatatca agcagggaaa gatttttcgt atataaaaaa
    28981 atatgggatt ataacaaaag gaactttaat aataaatcag aaaaagaaat atgatagatt
    29041 aaataaagat acaattgaaa gggcaatagt agaagctata aacaataatt aaaagtttaa
    29101 aaattaggag tatcaaaaat gaatatatta gaaattgttt taaatggagt taaagatact
    29161 atagtagctt ctatagttac actgaatgga gcatcaggat ggcttatgat aagttttata
    29221 ttggcaggtg tacttcacaa tgttttaact ccaagaaggt ttcaaaaaca acttggaaat
    29281 aagaaatttt cttctttaat taaaagtact atctcaggaa tgtttttacc aatatgtagt
    29341 tgtggagtaa taccacttgg aataagtatg tattattcag gagcatattt aggaccagta
    29401 cttgctttta tgacatcaac tccaataata aatccaatag ctgtagttct ttgtctaggt
    29461 cttttaggtc ctaaagttac aatcatttat ctaatagctg gttttttagt accattttta
    29521 gtaggatttt taggaaattg ttttggaaaa gaagaattat cactttataa tgattcagag
    29581 gaagaagtaa tagaattaga agaagaaaaa agaagtttta tggaaaatat gattgatggt
    29641 cttaaatggt cttttggtga attagccctt actattagta aatatgtagt aatgggtatg
    29701 gtttttgcag gatttataac aactattttt ccaaatagta taattcaaaa atatttagga
    29761 aatccaggtt tgctatctct tggaagtata gcaatacttg catgtgttat gtatgtatgt
    29821 gctgtaggac atataccgtt tatagcagcc cttgttgcaa gtggagcatc tcctggtata
    29881 gcgataacat ttctaatagc tggagcagct acaaatctac cagaacttat aagcatgttt
    29941 aaacttattg gaaaaagaac tgttattata tattctgtaa ctttgacact gtcctcaata
    30001 ataattggat atataacaaa tttactttta gtgaataata attcagtaaa tttagatgca
    30061 acaaattctt caatacagtt ggcaaataaa ctaatgttaa atatacctga tagttttgag
    30121 tatgtatgta ctattttaat tattttattt gcatttaaat caacaatacc aaagatgaaa
    30181 gaggtcatag gaaatcatgc ttaaaaagat agttataata tcctgtatag tagttgtgtt
    30241 aatcatttta tcaaaaatag ttgatgataa catcaaagaa gatgcttcta ttccaaatgt
    30301 gaataaagaa acattagaat attttagaaa aaattataaa gaagacataa taacttgtgc
    30361 tgaagaagat ttaaataatg atgggaaaaa agatttagta gttatatata aaaaaagcaa
    30421 taattcaaat gaaatggtag tcgtagtttc tgataaaaat agccactata taacaaagcc
    30481 aataccagca cctatagaga atcaaactat aacctttaaa aatattgatg ataaagcacc
    30541 aatagaagta atagtatcag ggtctaaaaa tggtaatgta ggatatgcta tttacagagt
    30601 agagggtaaa aaatttgttg atttatttgg cgaagatatg gacaaatgtt gctaaaaata
    30661 aaaataatac ataaaggtgg gaaatttata tgaaattatc taagaagatt caagcactaa
    30721 tcttatttgg tgtaatgggt acatctatat taacaggatg tagtagtaaa ccaaaagaaa
    30781 aagaagaagc aaaagctgga aaagatgatt atacaataac agtaggttat tataattgtg
    30841 accatatgac tgcgggacca gtagcagaat cggcaggaat atataaagat ttaggtctta
    30901 atgtaaaaac tgttggaaat ggtaaagttc ctgaagctat ggcagcagga aaaatggatg
    30961 caggttacat aggaactaag gggttagttg gagcaatacc taagggttca ccaataacaa
    31021 tagcagctaa caaccatact ggtggttctg aatatttaat agtttcaaaa gatataaaag
    31081 aacctaaaga tttaataggt aaaaaaattg caacagatat gagtgatttc ttatggacaa
    31141 gtgattatgg tccagaaaca ggtctaccaa ctgacccatc aaaatatgaa gttgtaaata
    31201 tggattcaga caaagataaa tatttagctc ttaaaactgg gaaaattcaa gcttttacat
    31261 cttgtgaccc ttggggttct gtagctgaaa atgacggtgc aggaaaaata atagcatcta
    31321 ctcaatataa agaaaaagct aatggcaaag aatataactg ttgttcattc tcattaaaca
    31381 aaaactttat aaaagaacat ccagatttag caaaaaaatt ggttctagca catacaaaag
    31441 caatagaata tatatataca aatccagctg aagcagctaa aatatttgca aaatattata
    31501 atgtagaaga agaagttgca cttagaacta tctataagaa gactgttgga gaaggtagaa
    31561 ctcttacttg gaaagttaca ggtgaagaat ataaaaataa tttacaaatg tataaagatt
    31621 taaaggcttt agatgatata cctaaatatg aagatacgat tgatacaagc ttattggact
    31681 cttgtggagc tgatgatttt gacaaattta taaaagaaaa agttaaccca gagtttcctg
    31741 aaggtatgag ttatgaagac tggaaagcaa aggtattata aataaatgga gaatataaaa
    31801 aatataataa tactttttat cattattttg ggaagtatat ttataatatt ttttaatttt
    31861 gaagataaag aagaaataaa aggaaaatta agaatagggg tatctgatga tacctctggt
    31921 tttgtaataa attatatggt aaatagagac tactttgaaa atataaaagt aagtgatata
    31981 atggatattt ttacaattaa tgattgctga gcaagtacaa tgcagtgggc tctgagttca
    32041 gaggaaatag atatagcaat catatgtaaa gatgctgcaa aacaatatgt aaatgtaaat
    32101 agtggatttg aaattgttgg tactgtagtt caaaattctg atatatttct attaagtgat
    32161 aataatcctg aaaagatagg agtcattcaa aatagagatt accagtcaga attggttaaa
    32221 aaatactaca agaatgtgga agtagctcca ttattaggga ctgcactagc atatggatta
    32281 gaaagtaatt tagtagatgg tgttgtaata gattgcataa agtcaattgg gttagagggt
    32341 aaaagaaaat ctacaactaa attaggagat tatgatacct atgtattagt tgtaagtaaa
    32401 gagtttaaaa aaagtaaagc atatagtgat tttataacac tttacaataa aagtgttgat
    32461 gctttaaaga ataaagctac atttaagaaa gcattaaaag agtacaggaa tataagaaat
    32521 atagatatgg aggaaataag caattggaaa ttaaaatttc taaagataaa agcgatagat
    32581 taactaagaa aaaaactgat ggtagtatgg atattttata taaaataata ctattagtta
    32641 ttatattttt agtctggcat tttgcagcaa aagatatagg gagttctttg ttacttccaa
    32701 tgccagtaga tgtaataaaa ggtttctttt tctgtgtgac agatgcagag acagtcacta
    32761 atctttttat aacattgcag agagtactta aaggttttat gtatgcatta ttgtttgggc
    32821 ttccaatagg atttattatg ggattttcta aaacttttga aagggtttta tctccagtag
    32881 tagattctgt aaggcaagtt ccaataatgg catgggttcc tcttactata gtatggtttg
    32941 gtataggaga tggtccaaca atatttttaa tagctttttc aggggttttc cctataattt
    33001 taaatactat tcaaggagta agagcaatat caaaggatta ttataatgca gctagaagta
    33061 tgggagcatc gccaattgtg atatttacaa atgtaattgt tcccgcatct cttccagata
    33121 tactaactgg ttcaaggatt gctataagta caggatggat gtctgttatc tgagccgagt
    33181 ttatagctac gagtgccggt ctcggttact caatggtaca agctcaaaca ttaatgcata
    33241 cagatgtatt aattgggctt atgatatttg cagctttaat aggatttata atagataggg
    33301 tattaaagtt tataaataaa atcctttgta gatggaggtt tgcagattaa tgaagttaag
    33361 tgtaagagat ataaataaga catttgtaaa taatagagta catacaaagg ttttagaaga
    33421 tataagtatg gatatagatg atggacaatt tgtctgtctt ttaggaccat caggttgtgg
    33481 aaaaacaact ttacttacta taataggtgg gtttcaaaaa tcagaacgtg gagatgtttt
    33541 tataaatgat aaaagagtta aaaaaccggg catagataga gcttttatat ttcaaaatta
    33601 tgctttattt ccttggaaaa ctataagagg taatgttcta tttcctatga aacagcagaa
    33661 aataccaaaa gaaaaaagag aagaaatgct agaagaactt ttggttatgt cagacttgaa
    33721 aggaaaagaa aaactgtttc cgcatcaatt atctggagga atgaaacaaa gagtggccat
    33781 gataagagct ttagcatgta atccagaggt attactaatg gatgaaccat taggagctgt
    33841 agattttcaa atgagacaaa atttacagga agagctagaa cgaatatgga taaagaagaa
    33901 aataactgca ttaatggtaa ctcatgatgt tgatgaagct gtatatatga gtgatagagt
    33961 tatagtaatg tcgagagata aaggaagaat tattgatgat ataaatatag atattccaag
    34021 acctagaatt agaggaagcc aaaaatatga agagtacaaa aacaaattaa ctgatacttt
    34081 atcaaagtgt tatgaagttt aaagaggagt agacatgagt caaatagaaa aatacaatag
    34141 tttggataat acacaacaga aaataagaat ctctattatg gatatgataa tagataaagg
    34201 ttctagtgtt acacttcaag aagtgactga atatgtaagt aaaaagttga atatagaaaa
    34261 agaatatata gaaaggacac tacaatattt tatttatgaa aatataatgg ttgttgatgg
    34321 gaatagtata aattttatat atcctgtatc agcattgcaa acaaatcata aagtaacttt
    34381 gagagataat agaagtttca gcgcaatgtg tgctatagat gctataggaa cctcttgcac
    34441 attcaaccaa gatataaaaa taaactctat ttgtagtgct acaggtaagg aaatagaagt
    34501 aattataaaa aatgaaaaga ttgagtatgt gaataatcca aacttaagag tgcttcatat
    34561 aaatcttgat aagcatctaa attgggctgc tagttgctga aatataatga atttcttctg
    34621 gacgaagagt gattttgatg cttggacaaa cgaagcggga ttatctgatg atgaagatat
    34681 atattgttta gatattaatg aggcaatagt agaatcatat aaaatattta aactcaaaca
    34741 aaaggtacta tcatagatat acatatatga aaaactaaaa atgaccttta gataaaaatg
    34801 ataggtaata tccatactat ataaattagt atagagtagg gatgtgaaaa gtatttaaat
    34861 ctaaaggtat atttttagtt tttttagatg attagatagc cttattaagt atatatttat
    34921 ttataacctt tgcaactcca ttttcattat tagtatcagt aacataatct gcaatttcct
    34981 ttatactatt acgtgcattc cccatagcca caccaagacc tgcatacttt atcatatgtt
    35041 ggtcattttc ttcatcgcca acagcaatag cattttctat aggtatattt agattcgtac
    35101 ataatgtttt aagagcagtt cctttattag tagttttacc taaaaattct agataaaaag
    35161 gagcagacct tactatagta tatttattga ataaattttt aggtagttgc tgtatgattt
    35221 cttccaatct ttctggttca tcaactatca taattttaca gattttaata gattcatcaa
    35281 ttttatcttt ttgtatatat ttgacttcta tattatttaa tttcgcttca tgaagtgtat
    35341 attttccagg tgcttcattt ggtgtaatta aatttgtcat tgtatttatg tgtattttag
    35401 tcttatattt tttacaaacg ttattatata taaaatcaaa atcatctaaa gtcatttcta
    35461 catcatgtat gattttctca cttttaactt cttgaataat tgctccatta aagcatataa
    35521 cataatcacc ttcatctgtt aaatttagtt gatttagaag ttcttttaca ccaggaagag
    35581 gtctgcctgt tgttataact acttttgccc cagccctttt tgcctcctga atggactcaa
    35641 agacttcagg agtaatcctt ttttgtgtat ttaatattgt tccatcaatg tctagtgcga
    35701 ttaatttgta catatcaacc tccaataaat tatatactca aatttcctgt gaaaacgttg
    35761 acacagctag tgttgaacaa agtttcagtg ggaaatatgg tttgttttgt atactattat
    35821 atcaagagat aagtaattta gaaagtttaa taatattaat ttttgataaa aatattactt
    35881 atgtgagatg agaatgtaaa aactttgtaa tcaataattc caaaattctt aattacaaat
    35941 aatggtatcg tttgcattgt taatataaat aaatgtatat tatatagtta gaagtttgaa
    36001 taaatagact gatggtaatt tgttatatta gttagttttg tgttataaaa tattgtaatt
    36061 ccattaatca ta
//
LOCUS       DAMJWO010000041        34792 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.042, whole genome shotgun sequence.
ACCESSION   DAMJWO010000041 DAMJWO010000000
VERSION     DAMJWO010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34792
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.042"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(108..764)
                     /locus_tag="PC366_002029"
     CDS             complement(108..764)
                     /locus_tag="PC366_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2577556.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVVIKRRDLMEKIADVITKKQQEILVEMDKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGASIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            complement(819..1448)
                     /locus_tag="PC366_002030"
     CDS             complement(819..1448)
                     /locus_tag="PC366_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDF2577557.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSKHKEIELSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERMNLLNECSLKECDYLSENGAKLFDDIEDTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFIDFECPGNTGLHKGENNKLIIERNKLINPI
                     YVGDTQGDANSAKFVGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            complement(1579..2220)
                     /locus_tag="PC366_002031"
     CDS             complement(1579..2220)
                     /locus_tag="PC366_002031"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HDF2577558.1"
                     /translation="MKICIVLNGEIEDYEVTRDIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTVSVTAI
                     KGDAKGVTLTGLEYPLDNYYMKYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            complement(2229..2900)
                     /locus_tag="PC366_002032"
     CDS             complement(2229..2900)
                     /locus_tag="PC366_002032"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDF2577559.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPVDTIKHVLPDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVAEVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            complement(2905..3789)
                     /gene="rsgA"
                     /locus_tag="PC366_002033"
     CDS             complement(2905..3789)
                     /gene="rsgA"
                     /locus_tag="PC366_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDF2577560.1"
                     /translation="MLEGKIIKGISGFYYVDTYNGIYECKARGIFRKQKITPLVGDRV
                     KISIVDEDEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKNIYELSGYKVIPVSNITKLNIDKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVTNGEISKERY
                     DSYIQLLHEIRQNNSRRY"
     gene            complement(3887..4624)
                     /locus_tag="PC366_002034"
     CDS             complement(3887..4624)
                     /locus_tag="PC366_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF2577561.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTILNEKNFSVKLFKADISNREDVENMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITD
                     EDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            complement(4732..6747)
                     /gene="pknB"
                     /locus_tag="PC366_002035"
     CDS             complement(4732..6747)
                     /gene="pknB"
                     /locus_tag="PC366_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HDF2577562.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPTLAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     EEEEEEEEEIMRAKKNQRPKSTPSKRTKKKKKKQESPKSRRRLKVIAAVLILILCAQV
                     FLAYKFLFAGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCII
                     SQTPEGGSTNVKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYE
                     YSSIYKEGTVLSQSPGAGSSRAQEGDEVNLYVSKGSEKSNTQTPTVPDKKPTTPENNT
                     PTEPGSNSGNSGGNSGSSNSGNSGGNSGNNGGNSGGSNSGNSGGSSGGSNSGDNGGSS
                     GGSNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            complement(6764..7516)
                     /locus_tag="PC366_002036"
     CDS             complement(6764..7516)
                     /locus_tag="PC366_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HDF2577563.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            complement(7536..8567)
                     /gene="rlmN"
                     /locus_tag="PC366_002037"
     CDS             complement(7536..8567)
                     /gene="rlmN"
                     /locus_tag="PC366_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDF2577564.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     DDMNNIPKSLRNKLEEVSCIGNIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIEEILNACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            complement(8575..9900)
                     /gene="rsmB"
                     /locus_tag="PC366_002038"
     CDS             complement(8575..9900)
                     /gene="rsmB"
                     /locus_tag="PC366_002038"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HDF2577565.1"
                     /translation="MDAREVGFKVLCDIEKNDNYSNIAINKHFKNLEISDMDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANNEKPSIYIRTNTLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEGSFVLDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLINSTVNRLGLKNVFVERFDASEIDENSISKFDYVLADVPCSGFG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASKYVKVGGTLVYSTCTIQDVENINIVTS
                     FVEENHNFEFVPIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            complement(9962..10663)
                     /locus_tag="PC366_002039"
     CDS             complement(9962..10663)
                     /locus_tag="PC366_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HDF2577566.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            complement(10732..11484)
                     /locus_tag="PC366_002040"
     CDS             complement(10732..11484)
                     /locus_tag="PC366_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HDF2577567.1"
                     /translation="MTDIKKYLTSVGILILILGILIGVVNFFIISLTQIFSLMINIII
                     ISLILIILCSTAVTYRVIKGKYVNSNIMKINFNIVSGLFPIISFIASSFGMSKSDIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCKECGRCNVGELI
                     KLKEKTNVKIFVATGGTLARKIIMDNKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDMMDIEKAIDFLTGKNILICN"
     gene            complement(11494..12423)
                     /locus_tag="PC366_002041"
     CDS             complement(11494..12423)
                     /locus_tag="PC366_002041"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HDF2577568.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKEFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTIYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            complement(12438..12878)
                     /gene="def"
                     /locus_tag="PC366_002042"
     CDS             complement(12438..12878)
                     /gene="def"
                     /locus_tag="PC366_002042"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDF2577569.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEELIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHEIDHLDGILFVDKIEK"
     gene            complement(12896..15421)
                     /gene="priA"
                     /locus_tag="PC366_002043"
     CDS             complement(12896..15421)
                     /gene="priA"
                     /locus_tag="PC366_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HDF2577570.1"
                     /translation="MNNILNLSRGFIMKKYAKVIVRSNTIYTDNLFTYQIPVFLSDVI
                     KIGHRILVPFGKGNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWM
                     KNRYLCTYIECINLIYPKGYKLNNYKVVLLGESLSGLNEIELKEKISTLSDKNREIVE
                     KVIDSKGKIKVDKLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESD
                     KIDDYIEQNKINVGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLE
                     FKDYYREPKSIYKSVLKSIKLNNEQQEAVDEIKSNMFVDDKKPYLIHGVTGSGKTEVY
                     MEIIEFALNQGLDSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAV
                     KAGKVRVLIGARSALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNI
                     TLILGSATPSIEEYYRAKSGEYKLINIKSRANDKPLPNIEVVDMKDELDKGNRSIFSL
                     KLQKEIRYAIEENNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRC
                     HYCGYEKEIPKECPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGAL
                     DEILNKFKDKEADVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLIT
                     QVSGRAGRADKEGKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNML
                     SVVVSGEDERLVIKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQIL
                     FKDENIEINLLKGIIKYICITKRDLIFDKNINVSIDINPNSVL"
     gene            complement(15660..16859)
                     /gene="coaBC"
                     /locus_tag="PC366_002044"
     CDS             complement(15660..16859)
                     /gene="coaBC"
                     /locus_tag="PC366_002044"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HDF2577571.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVKPLAFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GTGKLANPDIIVEEVLTNLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAIARGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILIGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            complement(16864..17130)
                     /locus_tag="PC366_002045"
     CDS             complement(16864..17130)
                     /locus_tag="PC366_002045"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HDF2577572.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKTKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            complement(17133..17750)
                     /gene="gmk"
                     /locus_tag="PC366_002046"
     CDS             complement(17133..17750)
                     /gene="gmk"
                     /locus_tag="PC366_002046"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HDF2577573.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLEELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            complement(17780..18661)
                     /locus_tag="PC366_002047"
     CDS             complement(17780..18661)
                     /locus_tag="PC366_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HDF2577574.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            complement(18665..19495)
                     /locus_tag="PC366_002048"
     CDS             complement(18665..19495)
                     /locus_tag="PC366_002048"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HDF2577575.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKINLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDRELKVTSMLM
                     GVPHTVVIVDELDVDDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGVLEV
                     "
     gene            complement(19782..20816)
                     /gene="ltaE"
                     /locus_tag="PC366_002049"
     CDS             complement(19782..20816)
                     /gene="ltaE"
                     /locus_tag="PC366_002049"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HDF2577576.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDESGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVSLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGSKEFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            21112..22887
                     /locus_tag="PC366_002050"
     CDS             21112..22887
                     /locus_tag="PC366_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HDF2577577.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTVKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDDISKDLFIKNLEELEGPIFKSIYSKFLGISPIIAKEICYRAG
                     VNQNAIIKDISDEQFDSLHKVFCNLFNDINSNKYSPCIIIDKKVDKVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEIANFYDENCNDVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIVLSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFVSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            complement(23102..24754)
                     /locus_tag="PC366_002051"
     CDS             complement(23102..24754)
                     /locus_tag="PC366_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2577578.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYTYLTESYSYISQSENNIETCSHSKEKSLLNAPDKFEEYLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGLLEDMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRADFEYQEYVKEKKRLEKALLYKKALS
                     DGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKVSKEMNIK
                     IQDGMEIISKNLLEVKDMTLKLENKLLLDNVSFKIKRGKKIALLGDNGCGKSTLIKEI
                     LADKNDNIKINNKVKVGCFDQNQSLLDEEKSVLYNTKVNSSFDESFIRINLSLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLVFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDAKIREFDCNYDEYIISRNKKTPSRDKQIKKENLLV
                     LENRLTTVISMLSIEKDNLKKELYESEYNELLKQITKLKNSF"
     gene            complement(25053..26264)
                     /locus_tag="PC366_002052"
     CDS             complement(25053..26264)
                     /locus_tag="PC366_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HDF2577579.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKIVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFSMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLLLRLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAVILLIGLGTTYLSNKGISIGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEEE"
     gene            complement(26548..27081)
                     /gene="pyrR"
                     /locus_tag="PC366_002053"
     CDS             complement(26548..27081)
                     /gene="pyrR"
                     /locus_tag="PC366_002053"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HDF2577580.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            complement(27440..28387)
                     /locus_tag="PC366_002054"
     CDS             complement(27440..28387)
                     /locus_tag="PC366_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDF2577581.1"
                     /translation="MFYFLKVKVGDIMDEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKVEKAKYLVKEEDNIVIEIPEPKVLEVLPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRARLETGRTHQIRVHALSINHPLLGDFVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEAIKKIK"
     gene            complement(28356..28802)
                     /gene="lspA"
                     /locus_tag="PC366_002055"
     CDS             complement(28356..28802)
                     /gene="lspA"
                     /locus_tag="PC366_002055"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDF2577582.1"
                     /translation="MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLIDR
                     VRLGFVVDYFDFRVIWEYVFNVADVFVVVGTVFLCIYVLFFESKSR"
     gene            complement(29112..29891)
                     /locus_tag="PC366_002056"
     CDS             complement(29112..29891)
                     /locus_tag="PC366_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2577583.1"
                     /translation="MKKAIWGICICLLSIVGVYTYNHNTHNQNSSKETYTLNDNIKDD
                     YEDVIIKKGNEDEKILALTFDDGPDEDFTPQILDILKKNNVKATFFVVGEKVEYNKEL
                     LKRQYDEGHEIGNHTFTHINVAKNSYGSVEKEITDTQNIIKSVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKGMNIILWSNLDPRDWSNPGVDTIINTILTKVQNGNIILLHDYNTKRN
                     DKSQTIQALEVVIPKLKERGYKFVTVSELIQHLDKNKQVQK"
     gene            complement(29941..30423)
                     /locus_tag="PC366_002057"
     CDS             complement(29941..30423)
                     /locus_tag="PC366_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HDF2577584.1"
                     /translation="MDTKKYKDKLLKEREKLTNLVVDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDSALSKIENGTYGFCDLCHNQI
                     DLERLDILPDTNLCNNCAKKENALLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGTLRD
                     "
     gene            complement(30607..32028)
                     /locus_tag="PC366_002058"
     CDS             complement(30607..32028)
                     /locus_tag="PC366_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HDF2577585.1"
                     /translation="MVSFLGSIVVLIVGYFIYGTFVEKVFGINDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGLYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGIVVAI
                     ILGLLFFKKAKDIKEQNAHKLAS"
     gene            complement(32174..32944)
                     /locus_tag="PC366_002059"
     CDS             complement(32174..32944)
                     /locus_tag="PC366_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2577586.1"
                     /translation="MRAIIVEDEFPARKELRYFIENKSSIEVVNEFTNGIEVLDFIQE
                     NKIDVIFLDINIPHLDGMLLAKTLNQFKSRPKIVFITAYENYAVDAFSLDVFDYVLKP
                     YSEERIISMLNKLEKSEMSDIELSNSNSNLYKYKKETVNQEIEEITHKISLWKGDKLV
                     VIDIDDIYYCEANERQTFIYTEKEKFILKEGISEVENLINDKTFFRTHRSYIVNLTKV
                     KEIIPWFNNTYILKLKNSDYEVTVSRSKVKEFRLLMHI"
     gene            complement(32949..34151)
                     /locus_tag="PC366_002060"
     CDS             complement(32949..34151)
                     /locus_tag="PC366_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2577587.1"
                     /translation="MKTSILIALIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIVGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGVVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRTDNGT
                     LIVFYVKE"
BASE COUNT        11090 a         6390 c         3505 g        13807 t
ORIGIN      
        1 tgaaatataa aattaatatc aataaaacct actttttaat tttttaaata tttattttta
       61 atttatcttg tttttaattt actttgattt taaaatgtcc ttgactttta ttttataaat
      121 gtacatattt cttctactgg ttttttagat ggactcttca aattgtcctc tggcactcca
      181 agagctaaca ttgcacctaa aaaatactct cccttttcaa aaccagtttc tgcttctaaa
      241 acagcttcta tctcatctgc tgcatagttt tgacttgtca accaacaaga accatatcca
      301 agttcaattg ctgatagtgt aaagttttca attgaagcac ctagactctg catacctgga
      361 tttcttataa ataatttatc tatagtctcc ttaggtgcat ctataagctc taattcataa
      421 tatcctgatg gattatatac ctttgtaaaa actaatacta aaactggagc ttttaagtaa
      481 aatagtgtaa agtttttaac aaattttcta aatctattag ccttatccac tgatacttta
      541 tccatttcca caagtatttc ttgttgcttt ttagttatca catctgctat cttttccatt
      601 aaatcacggc gttttataac aacaaaatgc cagttttgaa tattcttgcc tgatggtgct
      661 gcacctgctg cttttatcat ttttaaaata tcttcatctg atacatcttg atttttaaac
      721 tttcttacac tttgtctttt aaaaatagta tcttgtaatt ccatttttaa atccccccat
      781 aactttttta ttattttaat ataattttta aactcatctt attttaatat atcatgttct
      841 aacaaatctt taaatgaatc tataaaataa tcatatacat ctacattccc aaacccatat
      901 ttggcatata taaaaggtat acctacaaac ttagcactat ttgcatcacc ttgcgtatca
      961 ccaacataga ttggatttat taatttattt ctttcaatta taagtttatt attttctcct
     1021 ttatgcaaac cagtattacc aggacattca aaatctataa aatactgttc tagtttatgt
     1081 gcttttaaaa aagattctat atatccagct tgacaattac ttactataaa taatttatat
     1141 tttttagata gtaatttaag agtatcttct atatcatcaa ataatttagc tccattttca
     1201 gataaatagt cacattcttt caaagaacat tcattcaata aattcattct ttcttcttca
     1261 cttaaatttg gaaataaacg atttgctatt tcctcaaaag aaagccccat aagacttcta
     1321 aataaatctt ttgtgacact taattctatt tccttatgtt tacttaaaac atcctgccag
     1381 actttgcata cttcttcagt tgaatcccac aatgttccat ctaaatcaaa aataatacta
     1441 tctaccacaa aaaatccccc ttatgtcaaa gtttattata tatttataat tatatactaa
     1501 aaagcagata caatcataaa tatattttac ttgattgtat ctgctctaca atataaaacc
     1561 aattgtcaaa atcaaatttt ataaatttct aactacaagt acacagcctt gctctacttt
     1621 aatcttacaa gaattactca acataacatt tgatattcca ataggtacag agtatttcat
     1681 ataataatta tcgagagggt attctaagcc agtaagtgtt acacccttag catcaccttt
     1741 tatagctgtt acagaaacag tgtcccctgg gtttccatac aatgaaattt cctcattttc
     1801 aactatatac atctcttctt tatcagaaag tatcctagaa tatataccat cttcttttaa
     1861 ataatataat agctttatat ttgcaagagt gtggtcaatc cttcccccta aagcaccaaa
     1921 aaaatcaata tgatttgctt taagtgtctt agctaaaaaa agacaaagct ctgtatcagt
     1981 ctcatctttt ttagatggaa atttttcaaa tttaacacct ttatttttat agaagtttat
     2041 cttttcttct tctactgaat ctaaatctcc taatatataa tctggcatta tttccatttt
     2101 ataagtgtga tttgcccctc catctgcaca tattatgcag tcataacatt ccttaattat
     2161 aatatctctt gtaacttcgt aatcttcaat ttcgccattt aaaacaatac agattttcat
     2221 tattaaattt aaactaattc ttcaagagaa gcattctttc taaataaatt aactgtttct
     2281 tgaatgtcat cacttccaaa tattgcagaa cctgctacta ttacattagc tcctgcttgt
     2341 acaacttcgg ctacgttttt agggcttata ccaccatcaa cttctatatc aatgtttaat
     2401 ccttgactat ctataatagc ttttaactct ttaatcttat ctaaaacaca aggaataaat
     2461 gattgtcctc caaatccagg gttaacagac attaataata ccatatctaa atcaggtagt
     2521 acatgtttaa tcgtatctac tggtgtagct ggattaagta ctacaccagc ttttattcca
     2581 tgtgatttta tattttgtat agttctatgt agatgaacac aagcctcctg gtgaacagtt
     2641 attatatcac atcctgcttt tacaaattct tcaatatact ggtctggatt ttctatcata
     2701 agatgagcat caaataccat atttatattt tctttcttta aacttttgac tacaagtggt
     2761 cctaatgtaa tgtttggtac aaagtgtcca tccattacat cgatatgaag atattcacat
     2821 cctgcacttt ctacttttct tacatcttct aataattttg caaaatctgc tgataatatt
     2881 gatggtgcta atttaatcat ttttctaata cctcctacta ttattttgtc ttatttcatg
     2941 tagcagctgt atataactat catatctttc tttagatatt tctccatttg taacagcttc
     3001 ttttatagca caattaggtt cattttcatg aatacacttt gaaccaaact tacaatcatt
     3061 aaatttatca aattctataa aataatcttt aagttcaact tcctctatat cttcaagtgc
     3121 aagggaacta aaacctggtg tatctgcaac cattccacca aattccaatt ttaaaagttc
     3181 agcgtgacga gtagtatgtt ttcccctttt tattttatca cttaccactc ctgtttgaag
     3241 tttaaaattt tcatctattt catttaataa gcttgatttt ccaactccag atggtcctgc
     3301 aaacactact acattttctt ttaattcttc ttttacttta tctatattta acttagtaat
     3361 attgcttaca ggaatgactt tatagccact aagttcatat atatttttaa cagtttctaa
     3421 tgtatcatta tcatctaaat ctgcttttgt aaggattatt acagtttcta aattttcttt
     3481 ttctgccaaa actataaatc tatctaaaag agataagttt ggtttaggat tttttattgc
     3541 gaatactatt aatgctttat ctacatttgc aataggaggt cttataagtt ctgtatctct
     3601 actgtcgatt tcttctaaga tacccttttt ttcatcttca tcaacaatgc ttattttgac
     3661 tctatcacca accaaaggtg ttattttctg ctttctaaat atccctctag ccttacattc
     3721 ataaatacca ttataagtat ctacataata aaatccacta atccccttta taatttttcc
     3781 ttctagcatc aaatgcctcc ctttataaaa tttatataaa cacatactgt ttatgaatag
     3841 tatatcgtgt tattctttcc tatttttata taataccaca ttttttttaa ataacaaatc
     3901 ctccgtttgg actaattacc tgaccagtga taaaatttga tttgtctgat gccaagaaaa
     3961 tagcacaatt tgctatatct tctggagttc ctagcctcat tagaggggtt tcttccacaa
     4021 gagcgtctat atcttcctca ttatatccag ataacatgtc agtattaatg acacctggag
     4081 ctatgctatt tactctaata tttgatggtc ctacttcttt agctaatgcc tttgtcatac
     4141 ctattatacc tgcttttgtt atagaataat gcacttcaca agacgcacct gatatacccc
     4201 agattgaaga tatattaatt atatttcctt ttttttctga tatcatgtat tttaaagcaa
     4261 cttgcgaaca ataaaagctt ccttttaaat taatattcat catattatcc caatcttcat
     4321 cggttatatc tgtaaacaac ttatcttgac ttacaccagc attgtttaca agtacatcca
     4381 atcctccaaa ttcttttata caataatcta ccatattctc tacatcttct ctatttgaaa
     4441 tatcagcctt aaaaagtttt acagaaaaat ttttttcatt taatatagta tacaactctt
     4501 tagcttcatt ttctgactta ttaaaattta ctaatacatt gtaaccttct tttgcaaaag
     4561 ctttagacat agctttacca atccctctag ctcctcctgt aattaaaacg gttttcttct
     4621 tcataaatac ttttctcctt atattataac caattcagta ttttatacaa aacaaactgc
     4681 cctttaaaga aaatattttc tataaaagga cagctcttat tttattaata tttattctgt
     4741 tttaccaatg tttgcgccag ttcctgatga agttcctcca ttatctcctg agtttgagcc
     4801 tcctgaacta tctccattgt ctcctgagtt tgaacctcct gaacttcctc cattatctcc
     4861 tgagtttgaa cctcctgaac ttcctccatt atctcctgag tttgagcctc ctgagcttcc
     4921 tccactattt cctgagtttg aacctcctga gttacctcca ttattgcctg agtttcctcc
     4981 actatttcct gagtttgaac ttcctgaatt tccaccactg ttccctgagt ttgaaccagg
     5041 ttctgttggt gtattattct ctggtgttgt tggtttttta tctggtactg ttggagtctg
     5101 tgtatttgat ttttctgaac ctttgcttac atataggttt acctcatcac cttcctgagc
     5161 tcttgatgag ccagcacctg gactctgact taaaactgta ccttctttat atattgagct
     5221 atattcatac ttaacagttc ccacttttaa gttattttct tcaataagtt gttttgcatt
     5281 actcaaagta agtcccacca cattaggaac agatgcctga cttgaacctt tacttacgac
     5341 aacatttata gtatcaccct ttttgacatt tgtacttcca ccttcaggtg tctgtgatat
     5401 tatacaattt tcatcaactt cactattata ctcttcactt tttacactca ggtataatcc
     5461 ttctttttca acagcacttt gagcttcttc taatgtcata tttacaagat taggaacagt
     5521 caaagattta ttgccaaacc ctccagcaaa taaaaactta tatgctaaga atacttgagc
     5581 acacaatatc agtatcaaaa cagccgcaat tacttttaat cttcttctag attttgggct
     5641 ttcctgtttt ttcttctttt tcttagttct cttacttgga gtactcttag gtctctgatt
     5701 ctttttagct ctcattatct cttcctcttc ttcttcttct tcttcatctt cttcataaaa
     5761 atcatcatag taatcttcat catcatccaa atcagctact tcaacaggct taaccacttt
     5821 ttcaggagct ggttttgcaa gtgttggatt tacaacttta ttaatttctt tttcatcaat
     5881 tttcttagtt gcaaaatcat catattcttt tataaaatct aaatcaatat ttttttctat
     5941 atactctata tcttctatca attcttcagc agtttgatat ctatctgcgc tagatttttc
     6001 tgtaagcttt tttattgtag ttcttacact ttgaggaatc ctaacttttt cttctgatgt
     6061 aaagtctata tcatcattaa tgtgttgaag tgctatagaa attggactat ctcccctaaa
     6121 tggaactttt cctatcaaca tttcatataa aactatacct agagaataca ggtcagcatt
     6181 attagttaca aatttacctt tagcttgctc tggtgaaaaa taatgcactg aacctattat
     6241 actaccaata ttagtcattg ttgaatttga aacagctttg gctataccaa aatcagccac
     6301 ttttactact cttccttcat ttgatatgag aatattatga ggttttatat ctctatgtat
     6361 aatccccttt ttgtgcgctg cactaagtgc catagctatt tgttttgtta tatctaatgc
     6421 agtatattca tctaatatac cttcatcttg tataatctct tttagattct tcccatctac
     6481 aaactccatt acaatgtagt gaacttttcc atcttcacca acatcataaa catttactat
     6541 atttggatgt gaaagacttg ctactgcttc tgcctctctt ttaaactttg ttagaaattc
     6601 atcatcatct acaaattcag gtctaagtac tttaagtgca acagtcctgt ttaataatct
     6661 gtctttagcc tcatatacaa aggccattcc tccatcacca atcttcctga tgatttcata
     6721 tcgatttcct aaaattgtat ctcccacaat atcaccgtcc taattatact tttatcacta
     6781 taaccgaaac attatcttta ccagaaacat cattggccat acttatcaat tcttcactta
     6841 tattactagt tctctcatat tcataatcta atattaaatc tcttatatct tcatcatcaa
     6901 taaacccagt taatccatct gtcgcaagaa gtattatatc actttttttg atttctttct
     6961 taaaaatatc tacaacaacc atatcatctg ttccaattgc tctagttatt ctatttctct
     7021 gtggatgtct tcttgcctct tcttctgtaa tgacatgggc catcataagt tcttcaacca
     7081 cggaatggtc tatagttatt ttatcaaatt tttcatctgt taacaaataa catctgctat
     7141 ctccaacatt tgccacatat aagacattat tatacactat agccgtaact aatgtagttc
     7201 ccattccttc aaattctata tcttccatag attttttgtg cacaattgag tttacattat
     7261 tataagcctg ttttaatata tcatctatat agtctatttt tacattatca tgttgtaata
     7321 agttttcctt tagaaaatca attatatttt ctactgctaa tttactggcg acttcacctt
     7381 ttttatgtcc acccattcca tcagctatgg caaatattcc tattggacca tgttctgtat
     7441 ctataacttc tccctcacaa tagtcttcat tgttttttct tatttttcct atatgggagg
     7501 cacaactata aaccatacga cttcctcctt acaaattact tgtattttct tctcaattga
     7561 ccacaagctc cactaatatc agaacccata gacatcctaa ctgtggcagg tatattgttc
     7621 ttctccaaac tatccctaaa tttataaata aatgctttat ctggcttttc gtattctctt
     7681 tcttcaactt tatttattgg aattaaattt acatgacata gcataccttt taggagctta
     7741 gctaatgcct ttgcttcttt ttctgagtca tttactcctt ttataagaga atattcaaat
     7801 gtaacccttc tatttgtctt ttttatataa tatctacatg cattcaatat ttcttcaata
     7861 gaataagcat ttgctacagg cataattttt cttcgttctt catcatatgg tgaatgaagt
     7921 gataaagcta aatttatagc tatttctaag tctgccaact catacatttt aggtactatt
     7981 ccacaagttg aaagagttat atgtctatac cctatattaa gaccattttt ttcgttaatt
     8041 atttttaaga attgttttgt attttcaaag ttatcaagtg gctcaccact ccccatcaat
     8101 acaagatttg ataccctctt accagtatct tcttgaattt taataacttg gtctaaaatt
     8161 tcccatggct ctaagtttct aattaatcca tccattgtag atgcacaaaa attacatccc
     8221 atcctacaac ctacttggtt agaaacacag acagtaactc tactatcata atccatcatc
     8281 acagtttcta ttatatttcc atcatctaat aaaaacaaat atttttttgt attatctacc
     8341 ttagattcta actttaattc tatatctata ttccctatac atgaaacctc ttctaattta
     8401 tttctcaaac tttttggtat attgttcata tcatcaaaag tttttgcacc cttatatatc
     8461 caagagaata tttgacttcc tctaaagggc ttttcatcta tagttttcat aaattcttta
     8521 agttcatctt cagtaaaatt ttttaatact atctttttct tttccattct ctcactacct
     8581 tattctcttt aattttgcta tgaaaaaacc atctatacca tgaatattag gatatatctt
     8641 taaatatcct ttatcttgat tgtctaagtc tacatttact gtatcaattg gaacaaattc
     8701 aaagttgtga ttttcttcaa caaaagaagt aactatattt atattctcca catcttgaat
     8761 tgtacatgta ctatatacta aagttccacc aactttgaca tatttagatg cattttctaa
     8821 aattttcttt tgtatagaag tgatgtcttt taactcttct tctttcttat acttaatttc
     8881 tggtttacgt cttattatac caaaaccaga gcaaggaaca tctgctaaaa cataatcaaa
     8941 tttacttata ctattttcat caatctcaga agcatcaaat ctttctacaa acacattttt
     9001 aagccccaat ctatttacag tagagtttat aagctttagt ttatgctcaa aaatatctct
     9061 agctactact tgacccgtat tgttcattaa agtagctaag tgagtagatt tccctccagg
     9121 agcactacat acatccaaaa caaatgaacc ttcttttgga ttaattactt tccctactat
     9181 catagaactt atatcttgaa ttgtaaataa accagcctta aataattcat ttttttctat
     9241 atttttcatt ttttcgactt taatagcttc ttctaccata ggaactttta aacatacaat
     9301 acccatttca cttaattttt caataagttc ttctctactt attttaagtg tattcgttct
     9361 tatatagata ctaggctttt cattatttgc ttccaacaaa tcttcagcaa attcttgtcc
     9421 aaatttatct atccagtttt ttataatcca agagttatag gaatacttta tagataagta
     9481 ttttacacta tcttcctcag ttatgtccat tatagtctct ttagctctta tttcatttct
     9541 aagaatagca tttatgaaac cagaagattt tttatcatat ttcttagata attttacagt
     9601 ttcattaact gctgcataat ctgatatact atctaaaaat aaaatctgat atgttcccat
     9661 tcttaaaaag attttaacat aagttgacat tttttttacc tttatttttg aaagtttatt
     9721 gattatataa tctaaataat atttattttc tattactcca taaattaact ctgttgcaag
     9781 tcctctatcc atatcactta tttctaaatt tttaaaatgc ttatttattg caatatttga
     9841 ataattgtca tttttttcta tatcacataa tactttaaat ccaacttctc ttgcatccat
     9901 ataaatttct cccttttatt aaacataaaa aagggttgtt tctaaacaac ccactttact
     9961 tttagtcatt tcttctttga gctattagta acaatctaag taattgaagt attgaaacca
    10021 atgctgctgc aacatatgtt aaagctgctg ctgaaagtac tcttctactt tgtcttgact
    10081 cactttcatc tataatacct aaattcccaa gttgaacgat tgctctactt gaagcattaa
    10141 attctacagg caatgttatt atttggaata acactgaagc cgaaaacaat agtataccaa
    10201 tttttaaaaa tggaccagcc ataataaatc ctaaaaatat taaaaaccaa gatatacttg
    10261 aagcaaaatt cactactggt actaaactac ttcttatttg aagaggcgca taacctttag
    10321 catgttgtat ggcatgacca cactcatgtg cagctactgc aacagaagtt atagatgttc
    10381 cataatatac atcttctgac aaccttacag cctttcttct tgggtcataa tggtcactta
    10441 gatgccctct aaccatttct atctttacat catacaaacc atttgaatca agtactcttc
    10501 ttgctgtttg ctctccagta tatcctcgac gtgtatttac tcttaaatac ttatttgttg
    10561 ttgaactcac tttaaattgt gcatatatag taagtaatat agctggaatt aatacaacca
    10621 ttgttgggtc aaatccccaa aaaccgccat atacagggta cataaataac actctcctaa
    10681 aatatatttt tattatacat cctcttaata ttcacttaac ttaaaaacag tttaattaca
    10741 aattaatata ttttttcctg ttaaaaagtc tatagctttt tcaatatcca tcatgtctac
    10801 attagtattt acacaaggtc cattaggtct tttgttaaat acacctaaaa caggaatttt
    10861 cttaatatct tgtattccag atgtcaaatc tctttcacat gcaacagcta caacagcttt
    10921 aggtttatta tccattataa tttttctagc tagggttcct cctgtagcta caaatatttt
    10981 tacattagtt ttttccttta gcttaattaa ttctcctacg ttgcatcttc cacattcttt
    11041 acaattatct atatcattag taacttttaa tttacaacta ttctcttgaa tacaatgagg
    11101 tattaaaatt attatatcct ctggattaaa attatattta ttactgtata tatattcatt
    11161 atttaacttt atatatattc ttctaatatc actttttgac ataccaaatg atgatgcaat
    11221 gaaagatata ataggaaata atccactgac aatattaaaa tttattttca ttatatttga
    11281 gttaacatac tttcctttaa ttactctata agtaactgct gttgaacata gtattataag
    11341 tattagtgat attattataa tatttatcat caaggagaat atttgagtta aacttattat
    11401 aaaaaaatta acaactccta tcaaaattcc taatattaaa atcaaaatcc caacacttgt
    11461 taaatacttc tttatatctg tcatactttt cacctaaccc aatactaaac cagtttctat
    11521 agtattccct tttatatatt caccaaccaa cattctcttt ttattcggca tctgaatttc
    11581 ttcaattaaa agtacattat ctatagtact tacttttatc ccatctttgc ttacatcaat
    11641 tattgtacct acatcttttg tgcttttttc atctaacact ttagttttcc aaactttcat
    11701 tatgacatca ttatagatag tataagcact tggccatgga tttactcctc taactaaatt
    11761 gtgtatttct ctggcacttt ttgaaaaatc tatgttacct aatgatttat tcattattgg
    11821 cgcataggaa aattcttcat gattttgtac ttctcttgga gcatttcctt cttcaattaa
    11881 tcttaatgtt tcttttaaag tttctgctcc tatattcatc attttatcat gaagttctcc
    11941 tgctgttata ttttcatcaa gatttacttc tgtctttagt atcatatctc cagtatctaa
    12001 cccttcatcc atatacatag ttgtaacacc agtcttttct tcaccattta ttattaccca
    12061 atttataggt gccgcacctc tatattttgg aagtaaagaa acatgaacat ttatacatcc
    12121 aagtttagga atctctaata tttcttttgg aagtatctgt ccaaaagcta caactactat
    12181 tacatctgga tttaaagatt taattttatc tataaattct ttatctctag cctttactgg
    12241 ttgatataca ggtatattat tttcaattgc cagttctttt actggactca tacctagttt
    12301 tttacctctt ccttttggtt tatctggttg agttacaaca cccaatattt catacttctc
    12361 atctattatt ttttgtaaac atggaactgc tatatcagga gttcccataa atactatttt
    12421 catcaaatca actcctacta cttttctatt ttgtcaacaa ataaaattcc atctaagtgg
    12481 tctatctcat gacaaaatgc tctagctaaa agttcttctc cctctaactc tattgtttcg
    12541 ccatttctat ttaaagctct gacctttaca taatttggtc ttctaacatt tccagcttct
    12601 ccaacaacac ttaaacatcc ttcctcatct atttgctccc cagatgtttc tattatttca
    12661 ggatttataa gttctataag ctcttctcca atatctatta ctactactct ttttaatatt
    12721 ccaacttgag gtgcagccag tccaacacca tctgcatcat acatagtttc tgccatatca
    12781 tctaataatt gtattatctt ttcatcaatt ttttcaacct tttttgattt ttttcttaat
    12841 actggttctc ctatttgaac tatttgtctt aaagccatta taattcctcc taaatttata
    12901 atacactgtt tggattaata tctatagata cattgatatt cttatcaaat atcaaatctc
    12961 gttttgttat acatatatat tttattatac cctttaagag attaatttca atattttcat
    13021 ctttaaagag tatttgccat ctataatttt gatttatttt tgatattgaa catggatttg
    13081 gacctaatat aaatcctaaa tcatttatac cccttttttc taataaataa atcaatgatg
    13141 catgcatatt ttttatattt tttatcacta atctttcatc ttcaccacta acaactacac
    13201 ttaacatatt attaaaagga gaatatccaa atgcttttct tatttttatc tcatcttcat
    13261 aaaaaccctc ataatcatat tcaatagcat gcttaatagc atagtgttca gtgtcataag
    13321 tctgaagtac tacttttccc tctttatcag ctctccctgc tcttccagag acttgagtta
    13381 tcaattgaaa tgtagtttca aaacttttaa agtctggaaa atttaatatc atgtctgcag
    13441 acaaaatacc tactaaagtt acattctcaa aatccagccc tttacttaac atctgtgttc
    13501 caataagtac atctgcttct ttatctttaa atttatttag tatctcatct aaagcacctt
    13561 tttttgaagt tgtatcttta tccattctca aagtttttat atctggaaaa atatatttta
    13621 attcctcttc aattttttga gttccaactc caaatggctt aacataagta cttttacatt
    13681 caggacactc ttttggaatt tctttctcat atccacaata gtggcatctt ccagtattgc
    13741 ttttcttatg ataagttaaa gatatatcac aattttcaca ttgaaacaca tatccacact
    13801 ttctacaaga tacaaaattt gcataacctc ttctgtttaa aaatagtatc acttgattat
    13861 tttcttcaat cgcataacgt atttcttttt gtaatttcaa actaaatata cttctatttc
    13921 ctttatctaa ttcatctttc atgtctacca cttcaatgtt tggaagaggc ttatcatttg
    13981 ctctactttt tatatttata agtttgtatt ctccagattt tgccctataa tactcttcaa
    14041 ttgagggcgt tgctgaacct aaaataagag ttatattatt ttttaatgcc ataaatctag
    14101 caacttctat agcattaaat tttggattct tctcagactt atatgatgac tcatgacatt
    14161 catcaattat tattaagcct aaggaattaa aaggtgcaaa taaagctgac ctagctccaa
    14221 ttaacactct tactttacct gctttgacag ctttgtaaac atcatgtttt tctccttcag
    14281 atagtttact gtggaacact ccaactaaat ctccaaacct actctttagc ctatctattg
    14341 tttgaggagt taatgctatc tcaggtacta agaatatact gtctaagcct tgatttagag
    14401 caaattctat tatttccatg taaacttcag tttttccact tccagttact ccatgaatta
    14461 agtatggttt tttatcatct acaaacatat tcgactttat ctcatcaact gcttcttgtt
    14521 gttcattgtt taattttata ctttttagta cggatttgta aatacttttt ggctctctat
    14581 aataatcctt aaattctagg gttattagct ttttcttact tagagaattt atactttgtt
    14641 ttgaagcatt taataaatcc aataaatcat ttatctctac attttcatta tttttaagaa
    14701 aacttaatat ctctttttgt ttacttccca catttatttt attttgctct atataatcgt
    14761 caatcttatc actttctaaa ctcaaagata tataacatac tttcttttca tttttgtgat
    14821 ttttatattc ccaacataat tttataattc catttttatt cattgtgtac aaagaactat
    14881 ttaagtttgg tatatatttt aacttatcaa ccttaatttt acctttacta tcaatcactt
    14941 tctctactat ttctctattt ttatcactta aagttgatat tttttccttc aattcaatct
    15001 catttaatcc acttaaactt tcacctaata ggactacttt ataattattt aatttgtatc
    15061 cctttggata tatcaaattt atacattcta tataagtaca caaatatcta tttttcatcc
    15121 aataaaccaa ctctaaatct tcttttctaa atattggatt ttcatctaat atatcaataa
    15181 tttcttttat ttttattttt tcatctaagc tatctgtaaa ttgaaataca aaggcttctg
    15241 ttggtttatt accttttcca aatggtacta atattctgtg cccgattttt attacatcag
    15301 ataaaaatac aggaatttga tatgtaaata aattatctgt atatatagta ttacttctaa
    15361 ctattacctt tgcatatttt ttcattataa aacctctact taaatttaat atattgttca
    15421 tattttaata tactttacaa gatattaaaa tctcagaatt tataagcaat ttcaagttat
    15481 taatattaac tttattttaa taattaacta ttaattatat tttatacttt atgacaaaat
    15541 aaatgctgaa aactacaatt taactgacat ttgcgagttt ttactcgcta aaattaaatt
    15601 gcagctttca gccactttag ctgtgataaa atacacaaat atcatattta aaaaaggtct
    15661 tatttctcaa gcaacgcttt aactttatct aaaataacat tggctacttc ttcttttttc
    15721 atcttaggat actcagtaat atttccctct acatctatta tttttacaat attagtatca
    15781 gctctaaaac cagcaccttc tttagttaaa tcatttgcca caataaaatc taaatttttc
    15841 ttttttattt ttcctttggc atgttctata aggtcattag tttcagctgc aaatccaatt
    15901 agtatcttat cttcttttat ttttcctatt tcataagcaa tatcataatt tctacttagt
    15961 tctattgata aatcatcatt cttcttttta atttttttgt cagaataagt ttttggttta
    16021 taatctgcaa ctgctgcact ttgaattact attttatttt cacttaaatt tgatactact
    16081 gcttcataca aatcttgtgc tgactctatt tgaacaaatt ttttaagatt ttgtggaata
    16141 gaaagatttg taggacctga tattaatgtt acatcagcac ctctagctat agcttctctt
    16201 gctatagaat atcccatttt accagaagac ctattagtta aatatcttac tgggtctata
    16261 ctctctacag ttggaccagc tgtaactatc atactttgac cttttaaatc ttgctcttta
    16321 gtaagattag tcaaaacttc ctctactatt atgtctggat tagctaattt gcctgttcca
    16381 atatctccac atgcaagcct cccactttct ggttcaataa atttatatcc aaagctcttt
    16441 aaagtttgta tatttttttg aacaattgga ttttcataca tattagtatt catagctggt
    16501 gctataagaa cctgtgcttt ggttgccata acagtagttg tcaacatatc gtcagctata
    16561 ccatttgcaa tcttgcctat aacatttgca cttgctggaa ctattaagaa taaatctgct
    16621 ttttttgcta atgatatatg ttcaacttcc caagtttttg gttcttcaaa catatcttct
    16681 actacataat tttgactcag cgattgaaat gcaagtggtt taacaaattc tgttgctgat
    16741 tttgtcatta taacatggat atttgcattt agttttttta acttacttac aacatcacaa
    16801 gccttatatg cagctatacc gccacttatg ccaattacaa cagttttatc ttttagcatg
    16861 accttactcc tcttctgaaa tttgttggtg ttgctcagca tgatgtctag cttcttctat
    16921 ctctatttcc tcttctgtca ataatctata tgttattttt ccacttgcaa cttctttagt
    16981 tgctacacat acaggctttt ccttagtttt atttgaaaca tatggttctt ctccatcaat
    17041 taattttctt gctctctttg aaacagtccc tactaaatag tatctgttgt ctattttttc
    17101 tagtacctca ttgatagatg gttttaacat aattataatt cctccttaaa tttctctatt
    17161 ataatatttt tatatctgct aactttattc ttttcagatg atattatacc ttctatttct
    17221 ttagcagatg tttttacatc ttcattaaat ataaaataat cataatcctt aatcatttta
    17281 atttcttcat atgcacagct aaatctcttc tctatttcag cttctgtttc tgtacctctt
    17341 ccaacaattc tattttttaa ttcttcaagt gatggtggta gtacaaatat aaatactccc
    17401 tctgggcaaa cttcttttat ttgttttgct ccttgcattt caatctccag taatacatct
    17461 tgtccttttt ctaaacattc cattattgcc gcttttggag ttccataaaa attatcataa
    17521 atttgagcat actccaaaaa ctcacctttt tctatcatct cttcaaactt ttccttactt
    17581 atgaagaaat aatttactcc atcaacttct ccagttctgg gttttcttgt agtagctgat
    17641 acagaaagtt ttattgtatc attttcttta agtagttctt tgcaaatagt accttttcct
    17701 gcacctgatg gtcctgatac aactagcaat aatccttttt tcacaaacat ttaagcattc
    17761 cccttctaat attgtattct tactctatat tttgtatttg ttctcttatt ttttccaatt
    17821 cgctttttac ttctactact aaattagtta tatttatatc agatgacttc gaacctatag
    17881 tgttagtttc tctattcatc tcttgtatta agaaatctat ttttctacct atagagtcgt
    17941 ctttaaatat agtattttta agttgcccta tatgactttt aaatctaact atttcttctg
    18001 ttatactgct tttatctgca tatattgcaa cttcttgtgc taatctattc tcatctatta
    18061 tacttgggtc atccagtaat tcacttattc tcaaattcaa tttttctcta taatcttcta
    18121 caacactact tgaatatttt tcaatctctt ctatatgatt ttttaataaa tcacatctca
    18181 tggcaatatc ttcagctaat tttttacctt cttcacttct catttctctt aatttgatta
    18241 atgcatcttc aactgcttga ttcaacattg accacaataa atcttcatct tcttcctttt
    18301 cttctatttt cacaatatca ggaaactttg caacattcat aacgctaata tcatctataa
    18361 tatcaaattt attttttatt tcttttagta tgtctatata ctgagatgct aatccctcat
    18421 caaaatttaa gtttacatct tctttgccta ataagtcaaa ctttatgtat aaatctactc
    18481 ttcctctttt tacataattt tttactaaat ttctaacttt atcctctaaa aatgaaattt
    18541 ttcttggaag acgtatgttt atatctgaat acttatgatt tatcgtttta cactctacta
    18601 aaaagtaata attatcatcc ttgtattctc ctcttccaaa accagtcata cttatagcca
    18661 ttaattaaac ctccaaaaca ccttcacata tttttactgc tggacctgtc atataagaga
    18721 aatctcctac atctatttta actgttccac cttgagacgt tacatttaca ctactttcta
    18781 ccatattaag taaattgcac actattgctg atgcagtcat accagtacca caacctaaag
    18841 tatatccaca acctctttcc caagtataaa catgtatatt atacttatct tctaccttta
    18901 caaaatttac attcgttttt tcaggaaata ttttattatt ttcaatctct tttccatatt
    18961 tacaaacatc atctacatct aattcatcta ctataactac tgtatgagga acccccatca
    19021 acatagaagt aactttaagc tccctatcta aaacctttat actttcttgc acaaaacgtt
    19081 ctttatttgt aagtacagga acatccttag ctataaaact tccttttccc atattgactc
    19141 ttatagagtt tatttctcta ttggtaagat ttatttttat atcttttata ccatctaatg
    19201 tatctactgt aaaactttct tttttaacta tacaattatc ataaacaaat ttacaaaaac
    19261 atctaaggcc atttccacac atagctgctc ttgaaccatc agaattataa tataccattt
    19321 ctacatctgc aacttttgaa tctttcacaa ctaacaatcc atccgctcct acagaaaatc
    19381 ttctatggca tacttttttt gctaaagcag tataatcaga tggatttatc tggtcgaatc
    19441 ttccatctat tgctataaaa tcatttccta ttccatgtag tttccaaaat ttcataagta
    19501 tcgctccttc gtaaattaac gcttaaacta ttataacata aaaaaattcc cataaactta
    19561 taatttatgg gaaaagtttt gtaatgacaa ctataatttg aggatgtgag ggagagttgt
    19621 cattacaatt agggtaatta tattatgttt ttaagctagt tctttctatg tttatatatt
    19681 aatatttcta tatgaatttt atgtatgttt tatttaaact gtctatgaat tttttaatta
    19741 aacatctggt aaccagctat aatcctttta gtagatatct attaacatac acctattaat
    19801 tctttaagtg tttttaaaac atagtctaaa tcttccttag taatatctac atgagttaca
    19861 aatctatatt caccattttc cattttatta atttttatat ttctttcaaa aaattctttt
    19921 attaaaacat cctcttttat aatatcttca ctcatcttaa aaaataccat acttatatct
    19981 ggattaacat tgtttacttc aatgccatca attttattta attcacaagc taaatatttt
    20041 gcattttcat ggtcttcatt caatcttaaa gtcatttttt caatggcaat tataccagct
    20101 gctgcaacta tacctacttg tctcattccc ccacccataa ctttttgctt tcttctagct
    20161 tttgctataa attctttact tccagcaagt atagaaccca ttggtgcagc taaacctttt
    20221 gacacacaga acataacact atcacaacac tttgctattt ctttagcttc tacacccaaa
    20281 gttaatgctg cgttaaataa tcttgctcca tctaaatgta ctggtaagtt gtgtttctca
    20341 gctatttttt taatttctct taaattatca agactcacaa cagttccacc tgaatatgca
    20401 ttttctacac atataagccc tgtctgtggt tcatgtatgt catctcttct aattgccttt
    20461 tcaacaagtt caggatttag agctccactt tcgtcttcat ctatagttct aagctgaact
    20521 ccagctatta cagcaggtgc cccaacctca tgagttacaa tgtgataacc tttaccaata
    20581 attatttctt gccctcttag gcaatgagta aatagagcta attgattccc aaaagttcca
    20641 cttggaagga aaatagcatc ttcttttcca actttagctg ctgctaattc ttcaagttta
    20701 tttacagtag ggtcatctct aaagattgaa tctccaacag gagcctttgc catagcttct
    20761 ctcatttcgt cagtaggcat agtaacagta tcacttctta aatcgataaa tctcattttt
    20821 tcaaccttct ttcatattta tatactatag aaccttaaaa ttgatttttt ctgtaaagtt
    20881 catatacttt catagcttat actctacaca ataattatac tatatttact ttatatttaa
    20941 tctactttaa attattaatt ttaaaaataa agtttcctct ctaataagta taaataatta
    21001 tacaatttaa atattaatct ctatcgttta aattccccct agtcacaaag cgtatattat
    21061 gtgtataatt aatttactga ctcattttgg tcaaagaaag gggtgctata aatggcatta
    21121 gatggattag ttatacattc aatagtcgat gaattatcat caaaacttac aggtggaaaa
    21181 atagataaga tacatcaacc tgaagatgat gaggtaattt ttaatataag aaataataaa
    21241 gaaaatttta gattggtttt aagtgcaagt gcctcaaatc ctagagttta tcttacaagt
    21301 aattatcaaa aagaaaaccc tctaaaagcg cctatgtttt gtatgttact tagaaaatac
    21361 atacaaggtg gaaatatagt agaaatttct caaataggtt ttgaaagaat aataaaaata
    21421 agtgttgaat ctttagatga attaaaagaa aagacagtta aaaatattat gattgaaatt
    21481 atgggaagac atagcaacat aataataact catggtgaag aaaataaaat tatagattct
    21541 ataaaaagag tcccttttag cataagtaga gttcgtcaag ttttacctgg tcatgattat
    21601 tcattaccac cagaacaaaa caaactcaac cctcttgatg atatatctaa ggatttgttt
    21661 attaaaaacc tagaagaatt ggaaggacct atctttaagt ctatatattc taaatttcta
    21721 ggtataagcc ctattatagc taaagaaatt tgctacagag caggtgtaaa tcaaaatgct
    21781 atcataaagg atatatctga tgaacaattt gattctttac acaaagtatt ttgtaattta
    21841 ttcaatgata taaattctaa caaatactcc ccttgcatta ttatagataa aaaggtggat
    21901 aaggtagttg atttcagttg tataaacctt acattattta gcgatttatc atatataaat
    21961 aaggatagta tgtctcgtat tctagaagat ttctatagaa ctaaagatat taaagacaga
    22021 attaatcaac gttcatctga tttaaagaag agtatatctg ttaagcttga tagactttat
    22081 aataaactta aaaaacaaga agaagaatta tcagaatccg aaaatgcaga catttataag
    22141 ataaaaggag aattgattac ttcatatatt tatatggtag aaaaaggtat ggaaagtatt
    22201 gaaattgcta acttctatga tgaaaattgt aatgatgtaa caatagaatt aaataaaaac
    22261 ttgacaccat ctgaaaatgc tcaaaaatac tttaaaaagt ataacaaaat gaaacatgct
    22321 aaagtcgaga tatctcatca aatttcctta aataaggaag aaatagatta cttagaaaac
    22381 atagttttaa gtattgaaaa ctgcgaaaat ttagctgaat tacaagatat aaaagaagaa
    22441 cttgctaagg ttggatatat caagactcaa aagaaaaaca gtaaaaagga tactatccca
    22501 tctacaaaac ctcatgaatt tgtgtcttct gatggattta aaatattggt tggtaaaaac
    22561 aataagcaaa atgactatct tacactaaga cttgctgata atgatgactt atggatgcat
    22621 acaaagaata ttcctggttc tcatgtaata ataaagtgtg ctggtaagga agtccctgat
    22681 aatactgtat ttgaaggagc tatgctagca gcattcttta gtaagtcaaa actttcttct
    22741 caggtgcctg tagactatac taagagaaaa aatgtgaaaa aacctagtgg ttctaaacca
    22801 ggtatggtta tttatgaaac taacagtact atttatgtta ctcctgaaga agaaacagta
    22861 gccaagctta aggttaaatc tgaataaatt ctgcactaaa tacaaaataa atgttagaca
    22921 agcacacatt atcattctaa ataaaaatag tggccttctt ataaagtaca ataataaggc
    22981 cactttctaa ttagcttact tttaattttc taacaaaata cttttctgtt ttaataacta
    23041 tacttatatt cccaacaaat attttcagtc ttcttatata gatgtaatta aaaagttaac
    23101 actaaaagct attttttaat ttagtgattt gttttagtaa ttcattatat tctgattcat
    23161 acaattcttt ttttagatta tctttttcta tagataacat agatataaca gttgtaagtc
    23221 tattttctaa tactagaaga ttctcttttt tgatttgctt gtctctacta ggagtttttt
    23281 tatttctgct aattatatat tcgtcataat tacaatcaaa ctcccttatt ttagcatctt
    23341 ttatctctat aatatagtta caaatatgtg atacaaatac tctatcatga gacactataa
    23401 gcatagtttt atcagtattt atcagtgcct tttccagtgc ttccatagat tttatatcta
    23461 agtaatttgt tggttcatca aatactaaaa aattattatc ttccaatatt attttacata
    23521 gtgctatttt taccttttct ccaccactaa gtacttttac ttttttgtag acatcatcac
    23581 ctttaaaccc aaataggctt aagtttatcc ttataaaaga ttcatcaaat gaactattaa
    23641 ctttagtatt gtatagaaca ctcttttcct catctaataa actttgattt tggtcaaaac
    23701 aacctacttt taccttgtta tttattttta tattgtcatt tttatcagcc aatatttctt
    23761 ttatcagagt actttttcca cacccattat cacctaataa tgctatcttt ttacctcttt
    23821 ttatcttaaa ggaaacatta tctaacaaga gcttattttc taactttaga gtcatatctt
    23881 ttacctctaa tagatttttg ctaattatct ccataccatc ttgaatctta atgttcattt
    23941 ctttagaaac tttaggttta ttctttacct caagtttatc aattctgctt tttatagcct
    24001 tcacatttga gtccaacttt ttcttattag tctgaccacc cattttgtgc aacctagctt
    24061 ctgaattacc cattcttttt ggtgtctttc ttatgccatc acttaaagct tttttatata
    24121 aaagagcttt ttcaagcctt tttttctctt taacatattc ttgatactca aaatcagctc
    24181 tttttacttc ttcatctttt tgcattaaat aatcagtgta attgcctttg taagctttta
    24241 gttttccatc ttctagttct aatatagttg tacataactc atccagaaaa cgtctatcat
    24301 gagatattaa taataatgct ccctcatgcc ttttaaacat atcttccaaa agcccaatgc
    24361 tttttttatc taagtttgaa gttggctcat cagctattat gatatttttc ttattactca
    24421 gcgcatctgc tatttttaac ttaacctttt cccctcctga taagtattct tcaaatttat
    24481 ctggagcatt taaaagactc ttctccttac tatgactaca tgtttcaata ttattttcac
    24541 tctgacttat ataagaatag ctttctgtaa ggtaagtata tccttcatca atttctattt
    24601 cacccaatat tgcttttaat aatgttgttt ttccttgacc atttgaacca actagaccta
    24661 ttttgtcatt ttctaatatt tcaagtttat ctatatccaa aattaattta tctgcataat
    24721 atttctttaa attctctact tttactaaca acataaaaaa tccctcctta acacacttaa
    24781 atataaggag agattctata aataggcata acaaataaac gtatagacta taatctactc
    24841 tccttaattt aagcattgca aataaagcca tcaaaatagg cttttcaaaa attacaatac
    24901 tttaaattat aaaaaataga ttatattctc attgtcctag ttaccttgcc ctttctttca
    24961 tttattttta atcattatat caacattaat tacaaatgtc tatagaaaat taactaattt
    25021 tagttattca atatacaatt tattctttaa atttattctt cttcaacttt aaaatcctga
    25081 ttatttaaaa ttctgtttaa tacaattcca acaattgcag ctaaactaag accagttatc
    25141 tttactgtac ttgttatagg gattccaata gaaatgcctt tattagataa atatgttgtt
    25201 ccaagaccta ttaataatat aactgctatt attaatatat ttatcttact ttctacacaa
    25261 gaactgtccc ttatagtttt taatcctaca taagttatca ttgaaaatag cattatacta
    25321 attccaccca taactgaacc tggtatactt tgaagaaatc caccaaactt tcctacacat
    25381 gcaagcaata tagcaaatat tgctgtacgt ctaagtattg aagggtcata gtttttagtt
    25441 atagcaagta ctgctgtatt ttctccataa gttgtattgg ctggtcctcc taaacaccct
    25501 gcaactatag tcgcaaatcc atccccaagt aatgttctat ttaatcctgg attttctata
    25561 aagtttttac ctactacagc accattagta gtcatatctc ctatatgttc cataaataca
    25621 gctaatacaa ctggagatat aatcacaatt gctcctaaac tgaacttagg aactgtaaag
    25681 ttcggtattg caaataaact tgcttctgta atagtagtta tatctactaa ccttaacagt
    25741 aaacagatta tatacccaga aaaaacggct attaatattc ctaattgttt tataaatcct
    25801 ctaccaaact tattggttaa aattgctatt gctaaagtta taaatgctat tacaaaatta
    25861 gctgaagcca tactaaaagc tgttggcaat aaatttaatc ctataactac tatcatagct
    25921 cctgtaactt gtgcaggaaa atataattta attttattta caccaactat ttttactata
    25981 atcgacatta taatataaat taatcctgct actattatac caccttgagc atatgctaaa
    26041 tctccaccat acgcctcttt agctgctagt ataactggta taaacgcaaa acttgaacct
    26101 aaaaaggcag gtacttttcc ttccgtacaa aaatgaaata tcaatgtacc aacaccagca
    26161 cagaaaattg caactgacgg attaaaacct gtcaaaatgg gaactaatac tgtcgctcca
    26221 aacatggcta atagatgttg taaagacatt attgtttttt tcataaaaac ctccaaaatt
    26281 attatatata aataaatcct ctgtttaatt aatatctttt aattaattat cattccctag
    26341 attctatttt ttaacctcta tatacttatt atataattta tcattatttt acattttacg
    26401 acatcaaaaa ctcaaataaa ggagaataaa aactacatta agactcacat ccataaaatt
    26461 ataatattta ttttgtgcaa tctatgtaag ctttatcctc ctccctgact attcaatgct
    26521 aagcttttat ataatactta aaactaatta ttctttgatt gtaactgaat cttctccatc
    26581 aatttctaat aaactgacag atataatttc atgtctagaa gtaggtacat tttttcctac
    26641 ataatctgct cttataggca actctctatg ccctctgtcc actagaactg ctaattgtat
    26701 tgatttaggt cttcctatat ctataatcgc atctagtgaa gctctcacag ttcttccagt
    26761 gtataaaaca tcatcaacca aaactactgt cttatcattt acattaaaat ctaaataagt
    26821 tcctttaact acaggttcaa catgaatttt ttccaaatca tctctatata aagttatatc
    26881 aatatctcct gtatctactt ttgttccttc tatttgttct attttcttag aaattctatt
    26941 tgcaattggc acacctctag tttttattcc aactaaaact agattttcta cacctttatt
    27001 tctttcaatt atttcatgac ttattctagt aattgctctt gctattgcct tttcatccat
    27061 taattgagct ttttctacca tatcataatt attgtcaaag atataatata tctatttgac
    27121 aaatctactc ctttctttta attttttata aatttatttt tatttaaaat ttcaatttaa
    27181 acaacaaaaa acttctcatc acaagacaag aagctcttat ataaaaaata tacagtgtaa
    27241 tttagcaatt gtcttacgat atctctgtat cgtttaaaga taatttttta atctatcaac
    27301 tcaaattata tatttatatt tcaaattttt caagcttttt taaacaaaat actttaatat
    27361 aagatatttt atttaaattt cactaaattt atttacttat ataaaaacaa aaaatgattt
    27421 ataagtatta tacaaatggt tattttatct tcttaatagc ttccttaaaa tactcaggta
    27481 attctgaatt aaattcgata tattccttag tggtaggatg tataaatccc aacttcttag
    27541 cgtgcaaagt ttgtcctttt aatttaaatt tagtttcttt tggaccatat acaaaatcac
    27601 ctaaaagtgg gtgatttata gacaaagcat gaactcttat ttgatgagtt ctaccagttt
    27661 caagcctagc tctcatatgt gtaaacttat caaatctttc tacaacttca aaatgagtaa
    27721 ttgcattttt tccatccttt actacagcca tttttaatct atccttagga tttctcccta
    27781 taggtttatc aacagttatt ttatcttctt taaccacacc atagcatata aattcatact
    27841 ctctagttat agtatgttcc tttaactgtt ctgctagaaa attatgtgca taattgttct
    27901 tagctatcat aagaagacca gaagtatctt tgtctattct atgaactata ccaggtctaa
    27961 taactccatt tattgacgac aacttatctt tacaatgata taaaatccca tttactagtg
    28021 tattttcata gtttccagga gcgggatgaa caaccatatc ctggggttta tttattatta
    28081 agacatcatc atcttcatat acaatatcta ttggaatatc ttgaggtaaa acctctaata
    28141 ctttaggttc tggtatctct ataacaatat tatcttcctc tttaactaga tatttagctt
    28201 tttctacttt attattgacc tttacttttc catcttttat aattttttgt atataacttc
    28261 ttgacatatc acctaattgt tctgctagat aaatatcaag tctaacttct tcttcctctt
    28321 caagtactaa aaactctttt acttcatcca ttatatcacc tacttttact ttcaaaaaat
    28381 aaaacatata tacataaaaa cacagttcct acaactacaa atacatcagc tacattgaat
    28441 acatattccc atataactct aaagtcgaag taatctacca caaaacctaa tcgtactcta
    28501 tcaattagat ttcctaatgc accagatata attaatataa ttcccaacct tccaaatata
    28561 tgtactttcc ttgtattaag atagtataat ccaaatactg ttgcaagtaa tgcaacaatt
    28621 ataaatatcc actgattatt ttgtaataat ccaaatgctg cacctctatt ttcgacataa
    28681 gttaaatgaa atacattatt tattattggt attgttgaaa catctaccaa attattcaat
    28741 acccatattt tagacagttg gtctaagcct atgagtagaa ttattattaa tatatatagc
    28801 aatgattttt ccccctataa attatttaaa aaccaatttt atttgaaaca cactattatt
    28861 attatacaaa aaaaatgctc taaagagcaa ctttattaaa attgtatttt cttaataaag
    28921 ctagagcaaa atttaaaata gtaccatctt ttttatattg cagattgcta catatttaaa
    28981 atcatattat tatgtataaa aaatttaaaa ataacatact aattaatact ttttgtgtgt
    29041 tttatagatt aaagattaat gatgtctgta ctttaaactt acaagcacca ctaatcttca
    29101 aacaaatatt tttacttttg cacttgctta tttttatcta aatgttgtat aagttcagat
    29161 actgttacga atttatatcc tctctctttt aatttaggaa ttactacttc taaagcttgt
    29221 atagtttgtg atttatcatt tcttttagtg ttataatcat gtaaaagtat tatattacca
    29281 ttttggacct ttgtaagaat agtatttata attgtatcta caccagggtt agaccaatct
    29341 ctagggtcta agtttgacca aagaattata ttcatgcctt tagaaactat aatatcacag
    29401 acacttttac tcatggctct atatggaggt ctaaatatct ttggttctac tcctattaca
    29461 ctttttataa tattttgtgt atctgttatt tctttttcaa cactaccata actatttttt
    29521 gcaacattta tatgtgtaaa tgtatgattc cctatttcat gcccctcatc atattgcctt
    29581 tttaataatt ctttgttata ttctactttt tctccaacta caaaaaaagt tgcttttaca
    29641 ttatttttct ttaatatatc aagtatttgt ggtgtaaaat cctcatctgg accatcatca
    29701 aaagtcaatg ctagaatctt ttcatcctca tttccttttt ttattattac atcttcataa
    29761 tcgtctttta tattgtcatt taaagtatag gtttcttttg aactattttg attatgtgta
    29821 ttatggttat atgtatatac acctactatg gataataaac atatacatat accccatatt
    29881 gctttcttca tgtcattacc tcttttctaa ttcattctaa caatatatga tgtcaggctt
    29941 ctaatctctc aatgttccat ttttatttaa atcagttaaa tttgttaggt cttctgaata
    30001 aaagttagaa tcttctacat caggattttg cattgcatca cctaataaag cattttcttt
    30061 ttttgcacaa ttgttacata aatttgtatc aggtaatata tctaatcttt ctaaatctat
    30121 ttgattgtga cataaatcac aaaacccata tgttccattt tctattttag ataatgctga
    30181 atctatttga tacagtcttc cttcttcatg atttattaaa ctattttgca tattttgcat
    30241 atataaatcc gttcccatat ctccaatatg attgtcataa ctagataatt ctcctgatga
    30301 atatttttca ctagtatgtt tagtagtgtc tccaaacaag gtattatctt tcatatctac
    30361 gactaaatta gttaactttt ctctttcttt taataattta tctttgtatt ttttagtatc
    30421 cattttcaac acctctaatt ttaatattta tatcataaaa atagtatgtg gaaaactaaa
    30481 ttaaaaatac aataaaaaac aagatttgat tttttcaaaa aaaattgtag gtaaacttaa
    30541 aattcaccta caaattcttt acatatattt ttaatataat gtttttagtt tttgataata
    30601 attacattaa cttgctaatt tatgagcatt ttgctctttt atatccttag cttttttaaa
    30661 aaataaaagt ccaaggatta ttgcaactac aatacctatt ccattagata tattaactgg
    30721 aagtctaaat ccttcttttg cctgcattat ataactaaat gttactacag tcataaaaag
    30781 tgctggcaat gtagttatgt aatgattttt atttgctttg actaaatatg cagaaccagt
    30841 ccacaacatt atcatagcaa gtgtttgatt tgcccaagag aaatatctcc aaattatatt
    30901 aaaatctata aatgtaaggg caacccctac agcaaataat ggcaaagcta ttaaaaatct
    30961 atttttaact gcatcttgat tataattcat tgcatcagct attgttaatc tagcacttct
    31021 aaatgctgta tcccctgaag ttataggaca tgctacaaca ccaagtatgg ccaaagcgcc
    31081 tccaataggt cccattaatc caacagatac tgtatttaca acagttgctg ctccaccatc
    31141 attaaatatt acattaagct gaggtatacc atggaaatat gacatagctg ctgctgccca
    31201 aactaaagct attatacctt ctgcaaccat tgacccataa aatactggtc ttgcctcact
    31261 ctctttctca acacatctcg ccataagtgg tgattgagtt gcatggaaac ctgatattgc
    31321 tccacatgct attgttataa ataagtatgg gaataaaggt gttccatttg gattcatatt
    31381 ttgtaaattt atatttggta tgttataccc ctttattatt aatcctccag ctacacctac
    31441 tgccataatt aataatgctg ctccaaataa aggatatatt ttaccaatca atttatctat
    31501 tggtaaaaca gtagccataa tataataaag tattatcact ccaacccata tttgtgcgtt
    31561 tacacctgtc aatgtcttta ataatcctgc tggacctgtt acaaatacaa ctccaaccaa
    31621 tactaaaaga ataacactaa atattctcat tgctattttt gcaccatttc ctagataaag
    31681 acctaccaac tctgatgcag atgtaccttt gttcttcatt gataaatatc ctgaagcaaa
    31741 atcgtgtact ccacctgcaa agattgttcc aaacacaatc cacaaaaatg ctgatggtcc
    31801 aaataacgcc ccttgtatag ctccaaatat cggacctaac cctgctatat ttagaaactg
    31861 aattaaaaag attctcttcc atttcattgg cacataatct actccatccc tacaagctat
    31921 agctggagtt tggtttttgt cattgattcc aaaaaccttt tctacaaaag taccatagat
    31981 aaaataacct actataagta ctactattga acctaaaaag cttaccataa attcatcccc
    32041 ttagttttta tataattgct ttataaattt ttatgagttt aagaaaacta tttccagttc
    32101 aaatagtaat acttttttat gctaatataa atattaatta cattaagtgc atatttaagt
    32161 acatgaaatg actttatata tgcattaaca gcctaaattc ttttactttg cttctgctta
    32221 cagttacttc atagtcacta ttttttaatt tcaatatgta tgtattgtta aaccatggta
    32281 taatttcttt tactttggtt aaatttacga tataagacct atgtgttcta aaaaatgttt
    32341 tatcatttat aagattctct acttctgata tgccttcttt taatataaac ttttctttct
    32401 cagtatatat aaatgtctgc ctttcattag cttcacaata atatatatca tcaatatcta
    32461 ttacaaccaa tttatcacct ttccaaaggc taattttatg tgttatttct tctatctcct
    32521 gatttactgt ctctttttta tatttatata aattactatt gctattagac agttcaatat
    32581 cactcatctc acttttttct aatttattca acatagaaat aattctctct tcagaatatg
    32641 gcttcagtac ataatcaaat acatctaaag aaaaagcatc tactgcataa ttttcatacg
    32701 ctgttataaa aacaatttta ggccttgatt taaactgatt taatgttttt gcaagaagca
    32761 ttccatcgag atgaggtata tttatatcca aaaaaattac atctatttta ttttcctgaa
    32821 taaagtctaa cacttctata ccattagtaa attcatttac tacctctatg ctacttttat
    32881 tctcaataaa atatcttaat tcctttcttg ccggaaattc atcttccact attatagctc
    32941 tcatacttct actcctttac ataaaatact atcaaagtcc cattgtctgt tcttcttata
    33001 ttaagccctc ttccatacat cagtttaagc cttaaatgta cattataaag tccaatctta
    33061 ttttctggca tattatcttg atatacatta tttataattt cctcacttat acctatacca
    33121 ttatcctcta ttgatattct cacagtattt tctaatgaat aaggtaactt ttttatggat
    33181 attttcacta caccagctct accactttct aaaataccat gtattatcgc attttccact
    33241 aatggttgta taatcaaact tggaatcttt atatttacat cttctatatc ataagataca
    33301 gttagtaatt ctccaaacct agctttttct atctctacaa aagatttaac ttgttcaatc
    33361 tctttattta tatcaattaa gttatcacta tattcaagat tatatcttag ataagttgat
    33421 aaatttatta ttaactctct agccttatct ggactaaatc ttataaatga agctattgtg
    33481 tttagggaat taaacaaaaa atgcggatta atttgtcttt gaagtgcttt tatttctgct
    33541 ttatttctcg cttctatatc ttttttatct ttctcaatcc cctctactat agatataaca
    33601 aatcctattc caatctgtcc aacaattaaa ggtaaatata tcccaacaat tatttgaatt
    33661 gctaaagaat gtggatatga tattaagtat ataagtagta tagtaaaact ttcagaaatc
    33721 atacctacca atataccata cattactcta tgttgctttg gtatcctctt atatagaaat
    33781 cctgataata cacctgctag tatacttgat aaaagacatg gaacagatgt tatcccccca
    33841 atatccataa aatatctatg aatccctgaa aaaactcctg ctgtaatacc taccattgga
    33901 ccaaataaaa tgccacctga tactatagat attattctag tgtttactat tgaccccata
    33961 taatttatac cactataagt tccaaatatg gctaaaaaag taaaaactaa tgctatacag
    34021 accaagtcat taaaactata ttcttccttt tgaaatatct gcttaaatat ttttaacttt
    34081 gttattagaa gaaacagtac tacaatgagg cttgtctttt ctattaatgc gattaaaatt
    34141 gatgttttca tattccacct ttaaaaaata aatttttaca cactctaaat ttattatgtt
    34201 tgttgtaact tatatatttg aagtaatcct atctcgacat tttccacatt taacctttta
    34261 attaaataaa aaatggatat acttctatta acaactaata ctagctgact aacacaagct
    34321 tgtaataact tgtagttatc attaactcta caattctagt atttaatttt atactttaga
    34381 aatctctttt cttagaagta atactttcga atattatata atacaatgtt atgtagattc
    34441 ttactcatac aacatatttc tttaaaaatt ttatactatt ctttgttcaa atatctcatt
    34501 tgatttaatt gtgctaaaca cacattatca tctctctgtt atatatttat tatatagccg
    34561 tatatcgata aagtaaataa atcctatatt taaaatcata tgtttgatag taaatcatta
    34621 taatgtatat ttaccataat aatttgccaa ccttgaaagt cacttctata attagaagtt
    34681 aaataattct tctaaaaaaa atacctctaa attttatttt ctgaaataca tagttataac
    34741 tatttttatc acgtataaga ataaaaattc cagaaaattt ttattatcta ag
//
LOCUS       DAMJWO010000042        33477 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.043, whole genome shotgun sequence.
ACCESSION   DAMJWO010000042 DAMJWO010000000
VERSION     DAMJWO010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33477
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.043"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(790..1383)
                     /locus_tag="PC366_002061"
     CDS             complement(790..1383)
                     /locus_tag="PC366_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDF2577588.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
     gene            1944..2174
                     /locus_tag="PC366_002062"
     CDS             1944..2174
                     /locus_tag="PC366_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577589.1"
                     /translation="MRLDMDSMLYVLIYMTLLVSIIGSIFYFCKDLLNHKIKYVLIRD
                     IFVNRITYSEERLPKQYIVFQKYDIWRYCSLF"
     gene            2231..2881
                     /locus_tag="PC366_002063"
     CDS             2231..2881
                     /locus_tag="PC366_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDF2577590.1"
                     /translation="MDFISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQ
                     RFSVKKQQELAEKMEHIKEKYKNDTKELEKQIQVSSVESMKSMLGCLIVLVQMPVVYA
                     LYHVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQV
                     KFNKQMAVVTTITSLILTVRTPVAIGLYFITSAIYSLIEDICFRMYFNRKNRIVTK"
     gene            3095..3766
                     /locus_tag="PC366_002064"
     CDS             3095..3766
                     /locus_tag="PC366_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2577591.1"
                     /translation="MAKILVVEDEKRMQSIIVEYMQKGGYTCITANDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            3763..4893
                     /locus_tag="PC366_002065"
     CDS             3763..4893
                     /locus_tag="PC366_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2577592.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKFEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDAISHEMKTPLGIIRAYTEGLMDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKMRMEQVV
                     ENLIINAKKHVVYNGNLDLSITCENGLLLFEIYNDGRIIEQDEISKIWSKFYRSVQSQ
                     RKGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            5298..6143
                     /locus_tag="PC366_002066"
     CDS             5298..6143
                     /locus_tag="PC366_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577593.1"
                     /translation="MIKVGELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSLFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFVYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            6143..7171
                     /locus_tag="PC366_002067"
     CDS             6143..7171
                     /locus_tag="PC366_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577594.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDNYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFLICDLCFTVLLVV
                     FNIGFFEGVKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            7174..8187
                     /locus_tag="PC366_002068"
     CDS             7174..8187
                     /locus_tag="PC366_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577595.1"
                     /translation="MIGLRYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTML
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKDSILKEFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGAPLLIYLLGVN
                     TSGIGNLCYIMPSVATFNGIMEIINGNVIIIKDIVILVVHCVVWFMIYIILDKKRKLS
                     FSR"
     gene            complement(8669..9919)
                     /gene="cme"
                     /locus_tag="PC366_002069"
     CDS             complement(8669..9919)
                     /gene="cme"
                     /locus_tag="PC366_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HDF2577596.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHNIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLVMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIVAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(10005..10751)
                     /locus_tag="PC366_002070"
     CDS             complement(10005..10751)
                     /locus_tag="PC366_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2577597.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVAQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSNPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(10866..11888)
                     /locus_tag="PC366_002071"
     CDS             complement(10866..11888)
                     /locus_tag="PC366_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HDF2577598.1"
                     /translation="MNKNNCLDLIFEKVDPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKVVFEKYYNGYNADDTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTCSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKVIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWICKKDGVLWYSAMGTGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            complement(11888..14308)
                     /locus_tag="PC366_002072"
     CDS             complement(11888..14308)
                     /locus_tag="PC366_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2577599.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLALLYSVEGQIMCTMCDTPVSDNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEIRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKILINQGNLNTFGTNLVNDILSKTRHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSIKKLKDLGNTVI
                     VVEHDKNTIEMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSDKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLGAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQINSSDSEIGDEDDYAVIETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLERGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHDILNMSVSESVHFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKTLKENP
                     KSITGRYL"
     gene            complement(14394..15314)
                     /locus_tag="PC366_002073"
     CDS             complement(14394..15314)
                     /locus_tag="PC366_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2577600.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHFVDIYLPIEPF"
     gene            15924..16850
                     /locus_tag="PC366_002074"
     CDS             15924..16850
                     /locus_tag="PC366_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HDF2577601.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSISTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSENS
                     NAEIVTKNSDIFKNIEKYIDATINNNQKTMKYKHRDELFKNSNTNTYSRINQESIDKD
                     YDLIIHTGYETENETKKKELLKNNLNKKNLNKNTFENLDEDLTEDSTYKNPESIHEII
                     IRKLNSESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEP
                     TILFGYEFESYLNEESSLSACNYGDMCYEDMY"
     gene            complement(17038..17658)
                     /locus_tag="PC366_002075"
     CDS             complement(17038..17658)
                     /locus_tag="PC366_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2577602.1"
                     /translation="MVLINILLVDDHMLFAKSLSIALEEYEEIEQFYSTQDIHNLSEM
                     IQDKKIDIVLMDINLRGLSECDGLKVAYNLLETNSTIKIIILTGYDLPVYKHEAKKIG
                     IYGFLNKNISPDSLIDSLLKVYQGVTCFPSENTEVIIEDLTNMEKRILQLICSGKKRK
                     IIADELYISERTLSNHLQHIYDKLDVSSSVEAITKAIKMGYISPVY"
     gene            complement(17630..19213)
                     /locus_tag="PC366_002076"
     CDS             complement(17630..19213)
                     /locus_tag="PC366_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2577603.1"
                     /translation="MTNFNLKILFLGNYILSLLFMGISTSTETYMNIQSIIPLIISTL
                     LLIDITYITSCNVRENNIISLFCGLLALDSWYLLLSFVTTPIGTIIFKILSTVIVYVS
                     IKFIFLFLFQGSGYNFRKITDILLLITCIGAIVGAFISNRTYACMYGIQFVVSIISFL
                     YIIFYHLKRVVFVIKSEKKPISISVFITIIGFLTYYFFTLRISNHIGNFGIYLTVLVF
                     FMSIHGIALKENDSFPISTVFNIKQRAIFLFISILVISLVVLFANGNFSIILIAINVL
                     FMLIFLCNIILEFNLRDEKNKVVKNSKYTFALEKLQQEEQLKTEFSNFLHDDILQNLL
                     SIKNMMSKSYRPEVQDIIYETLNNLNTCIRNQMQDYHPVILKNLTVKENYQNLIESVS
                     SSFPQKNICVSFKCSDTLFLVEPYDILIYRLIKELLTNVYKHSNGSHAWIALALEKNI
                     IKLNINDNGVKNTSFKTPLDITKITFDIIKHKGIISIKEQVENLGGTISISDNIPHGV
                     CVQITIPMKGDGSYKYFVS"
     gene            complement(19357..21384)
                     /locus_tag="PC366_002077"
     CDS             complement(19357..21384)
                     /locus_tag="PC366_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2577604.1"
                     /translation="MNIFYMAIKNLKKNFSFYSLYLLSVSFVITVFFAFTSFSVNKIM
                     LEKISTDGRVESMCNVISIFLMAFVIFYMAYSNRFFLRRRTKELGIYALLGYRKFTIL
                     SLLTFENVLICSGAFITGLVLGALSHKGIVFGITALLNLSIDNSQIPFFNINAINKTI
                     IFIALVVLVLAISNGKFLYKTSLVKLIRHEKSAEKKLKFRKIPAFMGFIMILSGYCLS
                     LDILRGAKSVWVSIGFYQMGLITMIIIVIGTVLFINSFLPYIMQKSKKNKRTFYTDMK
                     IIAIPNFIYRIRSNSKTLIMLTLLSATTLTVSSVMALSLYYPIASVSRIAPSEIEFRV
                     EKNKQIEDVKQIVSQYTSNTDDIIFTQTNIYKVKSSSKDLPFEYEIGTSKNNLSNSSS
                     SKEVISRESGFECISFSDYYTLLKAQNRTKLLKQLTPLRDNECILMKYQPNNDGYSEN
                     GTIYPLLINGKETPVAVRETSLNNAISFANSVGTLIVNDSIYEQIAQNKLPMTSILSI
                     NGKSIKNNENLYSNISDYLDGSPYLQGYSHRINDLLSINSSTFLLIGFLVVLFFIAVG
                     SILYFNNISAISDSTSDYKILQKMGYDNIQIKKIIKKQVLPFFNIPFLLGILDCIFAT
                     LVYKTALMQNLLGNSFSQYIPVIIAIFLTSVVYLIYYILTIKSCCKIVLKN"
     gene            complement(21397..22146)
                     /locus_tag="PC366_002078"
     CDS             complement(21397..22146)
                     /locus_tag="PC366_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005340256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577605.1"
                     /translation="MNTILKVNNITKTYNKGQQPSLDKVSFNVSEGEFIGIMGASGSG
                     KTTLLNVLSTIDKPTSGDIFINNINLKSLNDTCAADFRKDNLGFIFQEYFLLDSLTIF
                     ENISVPLTLQKLNPDKIENMVKSLAERFDIASQLNKYPNELSGGQRQRASAVRAIVKH
                     PSILFADEPTGALDSNSATELLHSLQEANEELKTTILMVTHDAYAASFANRILIFKDG
                     HIIKELNKQPNNRHTFYELIIQEIAKLDTKR"
     gene            complement(22443..24095)
                     /locus_tag="PC366_002079"
     CDS             complement(22443..24095)
                     /locus_tag="PC366_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HDF2577606.1"
                     /translation="MNNKNLAILISGMMFFSSSSAIFADNTTKQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIENSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKSLNIKINKIVGNNIYKMSTNVLKEIDKIKKVENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSINFLNNRSIKKSYIVGGNKILSD
                     NTVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGINQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIKNKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQALPGSDILVCYYDEDDNEYDCKVIKDNILYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTQNISLDKAKSIALDAVPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIVDIDMDNDSDDDFDDNDKNNSNTNDNSSIISAEKAKSIMLDKVPGGK
                     IVKFKYDEDDKEYEGEIIKGKIEYEITINAITGKILEFEIDD"
     gene            24694..25815
                     /locus_tag="PC366_002080"
     CDS             24694..25815
                     /locus_tag="PC366_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDF2577607.1"
                     /translation="MEAKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTIATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFDSFKFIEEKKKEGKIKNIGFSFHDSAELLDKVLSEH
                     PEVDFVQLQINYLDWDNESIQSRKCYEVAEKHNKPVIVMEPVKGGTLAKIPEKAEKLL
                     NDYNPDMSISSWAIRFAASKDNVMMVLSGMSNMEQLLDNTGYMQNFKPFVQEEYNIID
                     EAVEIINESILVPCTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNY
                     TKTYGKASDCIECKQCEESCPQHIKIIDALKNVAETFEK"
     gene            25851..26264
                     /locus_tag="PC366_002081"
     CDS             25851..26264
                     /locus_tag="PC366_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2577608.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIKARKELLIEQRNQLAKRIEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEAVSYE"
     gene            26257..26796
                     /locus_tag="PC366_002082"
     CDS             26257..26796
                     /locus_tag="PC366_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2577609.1"
                     /translation="MSKNVLIVSASPRKGGNSDLLCDQFIQGVLESKNQVEKIFLKDK
                     DINYCTGCGACYEKEASCSQTDDMGEILEKMIGADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVAAADENVADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNV
                     GDIKGSKAMKQAYEMGKLA"
     gene            complement(26996..27481)
                     /locus_tag="PC366_002083"
     CDS             complement(26996..27481)
                     /locus_tag="PC366_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577610.1"
                     /translation="MSKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEECSKTIKDSITKT
                     RTCKKCNSKCIGGSSFDLDGKSYLTCIGSGHYFANMEEMDWKNLEKLITKENNIMQES
                     V"
     gene            28332..28709
                     /locus_tag="PC366_002084"
     CDS             28332..28709
                     /locus_tag="PC366_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDF2577611.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            29117..30922
                     /locus_tag="PC366_002085"
     CDS             29117..30922
                     /locus_tag="PC366_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2577612.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEASKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIYKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHGKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNVCKNKDINIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQ"
     gene            30999..31538
                     /locus_tag="PC366_002086"
     CDS             30999..31538
                     /locus_tag="PC366_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase family protein"
                     /protein_id="HDF2577613.1"
                     /translation="MQYAIELYYDKKTEKQLFDLSKKIADEKISTKYLEWKTRPHLTL
                     ACFNDVDEACCIDKLKGFAQNHKVIPAYIGSVGMFNDTKTVFVSPIMNSSMYQFQREL
                     YEVLQDFDSNGWEWYHPNRWVPHCTIALTGDDESEAFFRASDVLLREFKKISGEFVSI
                     GLVKITFPVEEIFTVNMNR"
     gene            32161..33375
                     /gene="dpaL"
                     /locus_tag="PC366_002087"
     CDS             32161..33375
                     /gene="dpaL"
                     /locus_tag="PC366_002087"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HDF2577614.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLRDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKSLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
BASE COUNT        12310 a         4173 c         5170 g        11824 t
ORIGIN      
        1 tagaaaatta atctaaagaa gtgtaataaa ctaatttagg aagtatagaa aattaattta
       61 aagaagtata atgaactaat ttaggaagta tagaaaatta atttaaagaa gtatagaaaa
      121 ttaatctaaa gaagtgtaat aaactaattt aggaagtata gaaagctaat ctaaagaagt
      181 ataataaact aatttaggaa gtatagaaaa ttaatctaaa gaagtataat aaactaattt
      241 aagaaatata gaaaattaat ttaaagaaat acaatacatt aatttttaag taacattaaa
      301 ttaatgtaag taaaataatg ttcatatgaa gatttaaagg tgcattttct gaagctaagt
      361 atatgttatg tctctatatc cggtgaagtt taatagctca agaaaatgca ctatttatga
      421 tgattatttt gttttatttc caattttgga aataactatt ctaattaaat ctaaaattat
      481 accataaata agaaaagaaa gtatagatgc tatgtaccaa taaatcgaaa ttgaccctgt
      541 aattgttcta catgggattt gcatgcctga atccataaaa acaaaaaaac tatcaatggt
      601 agaaataata gacaaaatag gatttaatcc tattagaata atactttttg agtcttgacc
      661 aatttggtgg atataaatct caaataatgc aattaaaaaa aacaaaatgt aaaagattta
      721 ataatttttt tcatcaaaat acctcaccta atataaattc tgtttgcact atttgcttac
      781 tataactatt tatctccatt cagtcacatc acttaattgt aatctaggtc ttcttgatgg
      841 ttcttcgtca ggataaccta aagatattgc tgccactaat tgactatctg tatttaacca
      901 ttcacataat tcacgatatg caaagtatac atcacaaatc caaagactac ctagacctaa
      961 ttccacagct gtaagcgaca tattctgaat tgcagctcca attgattgca tgtttgccat
     1021 ttcatagaat cgttcttcag gggatagctt ttctaaaggt gatttaccta atatatttaa
     1081 aataaaaatt gttactggag cttgtttcat gatttcaact gtgtaatttg caccagcgat
     1141 atgttgacga cttcctggaa gaagcccatt atcattaatt tcattttgaa tacctttgct
     1201 catggcttta agcatagatt ctttttcctt ttcagtgatg acaacaaaac gccatggttg
     1261 cctgttttta gatgaaggtg catttattcc agcttcaatt attttctcta tagtttcatg
     1321 tgaaatgctt tgatttttat attttctgat acttcgtctt tttgatatag aatcacttat
     1381 cattttaagt aacctccgtt tattttttgg aaaaatctat ttattttcta tttttaatta
     1441 ttttagcatt aatcagaaaa aaagtcattg attttagtat acaattatta acgattatat
     1501 taaggattgt atcaaaaagt atgtgattat actaagggat tatattagac attatattta
     1561 aaattgtatg aaaggttgta tttaatatta tattaagaga gatatatatt aggatttata
     1621 tatattaaga tttattatat tgagccctta tattaaatta aggattataa tttaaaaata
     1681 agctataaaa acccaatatt gttttgttca gagataaaaa agaatacttt aggtgatttt
     1741 tattaaaaat taagagtgat aagattatat actttataaa tgtaaatatg acgaataaaa
     1801 atgataaata taataatcta tatatttaca ttaggagttt tctatactat aattatttat
     1861 atttaaaact aaatataaat gttggaatta tttaggattt gaaattgtct aaagataaat
     1921 ataagtgatg aagaggtgat gtgatgagat tagatatgga tagtatgtta tatgtactaa
     1981 tttatatgac attattggta tctatcattg gaagtatatt ttatttttgt aaagacctct
     2041 taaatcataa aattaagtat gttttaataa gagacatatt tgtaaataga attacatatt
     2101 ctgaagaacg gttgcctaaa cagtatatag tttttcagaa atatgatatt tggaggtatt
     2161 gtagtttgtt ttaatttgaa atgaatctat tataaattct aaagtttaaa aataaaaagg
     2221 agagaataaa atggatttca tttcaagtat attgcaagga ttattaagta tattatttaa
     2281 ttttacaggt gattttggaa tttctattgt acttataact ttaatagtta aattagtact
     2341 tatgccacta tcattaaaac aaagattttc tgtaaaaaaa cagcaagaat tagctgaaaa
     2401 aatggaacat ataaaagaaa agtataagaa tgatactaaa gaattggaaa agcaaataca
     2461 agtaagttct gtagaaagta tgaagagtat gctgggatgt cttatagttt tggttcaaat
     2521 gccagtagta tatgctttat atcatgtatg tttagatatg acaaaggaat ttacaacaat
     2581 tataattcca tggattgcta atttaggtac atttgataat ttgtttatat taccttgtat
     2641 atatacatta attatgttag cttcaaattt agtgaattat ataccatatt taaaaataaa
     2701 ttctcaagta aagtttaaca aacaaatggc tgtggtgact accataacaa gtcttatact
     2761 aactgttaga actccagtag ccataggtct gtactttata acaagtgcaa tttattcatt
     2821 aattgaagat atttgtttta gaatgtattt taatcgaaaa aatagaatag tgacaaaata
     2881 atataattat tattagaaat attttagcct gctaacatag aaaaagttag taggctattt
     2941 ttatctatga tatcaattcc attaagaata gtctaaaaaa tactatcaaa atgctataaa
     3001 aaatactata aaaatactat aaaaaaatag ttgaaaaata aataaattaa tataaactaa
     3061 aataaagcct acaaaaaaga ggtgataaat agaaatggct aaaatactag ttgtagaaga
     3121 tgaaaaaagg atgcaaagta ttattgtaga atatatgcaa aagggaggat atacttgtat
     3181 aactgctaat gatggagtcg aggcacttac aatattaaag agcaacaata tagatttaat
     3241 gatattggat attatgatgc cgtatttaga tggattttca gtgtgtagag tttcacgtga
     3301 aatgactaat atacctatta tcatattgac agctaaaggt gaagaggagg acaaattaaa
     3361 gggttatgaa tatggcgcag atgattatat aacaaaacca tttagcccaa aagtactttt
     3421 agcaaaagtt aatgccttgt tacgtagata cactactgat attcccaaaa attcattgag
     3481 tttaggaaag atttttatta tggtagcatc aaggcaagtg tatgtagaag ataaattgat
     3541 tgatttaaca tataaagaat ttgaattatt gcgtttattt atggaaaacc ctaatcaagt
     3601 tttttccaga gagaagcttt taaattgtat atggggatat gattttgaag gaaacacacg
     3661 aactgtagat acacatataa aaaccttacg caaaaagctt ggtagtgaag gacaccatat
     3721 agttacatta attcgttcag gatataagtt tgaggttaag gaatgaatag tttaagaaag
     3781 attatagaaa aactgaaaaa tgtagatatt tcaaattgga ttaaacaaaa ttttggacta
     3841 tattcagtta gaaaaaaagt gtttttactt tctaaattat caggagcgtt aattatatta
     3901 ttttatctgg ttgttgaaga attttcgata aactctaaat ttgaattttg gatttggttt
     3961 ataatactgg ttatatttat tatgagtatt gattttttat tgggaaaatt tatttcagaa
     4021 ccaatcacat ctataaataa atctgcaaaa agtatgtccc aacttgattt ttctaatcca
     4081 tgtactgtaa atactaatga tgaatttgga gaactttcta ggagcctgaa tacaatgtct
     4141 acaaatctac aacaggcatt atcagaccta gaaagtgcaa atattcaact tgaaaaggat
     4201 gtaaataagg aaagaatgct attggaacaa agaaaggagt tggtagatgc aatttcacat
     4261 gaaatgaaga ctccacttgg cattatacgt gcgtatacag aggggcttat ggatgaagtt
     4321 gatgaagaaa aaaagaaaaa ttatatgaat gttataatag aagaaactga tagaatgaac
     4381 aatatgattg tatcattatt agacttatct gcattggaag caggagtttc taaacttaac
     4441 ccagagcgtt ttgattttat agagtttgtt gaaactgtgg caggtcgtct tttaattgat
     4501 ataccagatg ccaattttta ttttacatat gatttgccag agtatgaagt ttttgtagtg
     4561 gcagataaaa tgagaatgga acaagtagta gagaatctaa ttattaatgc aaagaagcat
     4621 gttgtatata atggtaattt agatttatcg attacatgtg aaaatggctt gcttttattt
     4681 gaaatttata atgatggtag gattatagag caagatgaga tttcaaagat ttggtctaag
     4741 ttttatcgta gtgttcaatc tcagcgtaaa ggaggttcag gtctagggct tgcaattgtt
     4801 tcacaaatac ttacaatgca agggttagaa tatggagtga ataatcgtga tagaggagta
     4861 gagttttatt ttatgattcc aattgatgaa taatttagta ttaatttata aattataagt
     4921 atctgatgta aaatattttt ctttgtatac gtaagtattt aaagagaata aaataaaaaa
     4981 cttaatgaaa aagtctaata aaaagtttaa tgaaaagtct tgttttcctg atgaaaacaa
     5041 gattttttat taagcttttt attatttcac ttcgatttca caagagagac actctgattt
     5101 caccaaatag aaataaaata ggttaaataa attaaaaaat agaagcgtaa ttaaataagg
     5161 ttacaagggg gagtacttat gaaatggtat acatggttga ctattatatt gataatattg
     5221 ctttctattc cgcttaaaat taaatttata aaatggtggg atagacgaca aaaaaatgat
     5281 aaaggaggtt atgatagatg ataaaagtag gagagttaaa attttcttat ggaaaagata
     5341 aacagatatt gcatggactt aattttgaag taaaagaagg agaaatcttt ggattccttg
     5401 gacctaatgg ttcaggaaaa tccacaacac agaaaatctt aaatggcgtt ttaaaaggtt
     5461 acaatgggca cgtatccctt tttgggaagg aagttaaagc atatacagag tctctatatc
     5521 aaaagattgg tgttttattt gaatttcctt atttatatac caatttaagt gcaattgata
     5581 atttagaata tttttcgtct ttttatccta aaaatcaaag gagagacata tatgaactct
     5641 tagatttgtt agagtttaag aaagagttta taaataagcc tgtatcatcc tactcaaaag
     5701 gtatgaagca acgtattagc atggcaagag cattggtaag taatccaaag ttgttatttt
     5761 tagatgagcc tactagtgga cttgacccat ctggagctgt actatttcgt aagattattg
     5821 aagaagaacg aaaaaaagga acaactatct ttttgactac tcataatatg ctagatgcag
     5881 atttaatgtg taacaatgtg gcttttattg cagatggcaa gattatggta atagataaac
     5941 ccaaaaattt aaaaatgaaa aatagcaata ataaagttga agtggaattt gtatataatg
     6001 gaaatcgaga tattgaaatt gtagatatac aagagttaga atctggaata acttttaaat
     6061 atgatgaaat cttaagtgta cattcaaaag aacctacact agaagaagtt tttattaaat
     6121 acacaggaag gatgttagtg taatgtattc taaatttttt accttagtaa aaaaagattt
     6181 ttggatgatg atttatggta aattttttgt gctgacactt ggctctctca tactttattc
     6241 gtgttatatt aattttggtt atgtaaagtt tatggatgaa gatagttatc acaataatgt
     6301 atatctatat aatccagaga atataagcat gagtgcatct ccattaatta atcaagtttc
     6361 ttctataggt gaattaaaag caaaacttga tgaagataca agtgcagttt gtattgatat
     6421 gagttccagt aagccgaaag taattttaca tgaaagtatt aaaggagttg acaattatag
     6481 agctgactat gcattgtcat tattatcatc agaaaaagac cataatagca aaatatcaga
     6541 caacaatgca ataattcaaa ttaatgataa ggatacatct gagataaaac aaagaaaaga
     6601 catgacttgt gagattttat tctttgaaat tgtagctatt ggatttttag ggattgcctc
     6661 tttattattt aaagaaaagc agatgggagt aatgcgtatt actggtattt tacctgtaaa
     6721 aagaagtctt tttatattat caaagatatt tgcttttttg atatgtgacc tatgttttac
     6781 agttctttta gtagtattta atattggatt ttttgaagga gtaaaaatac ttccacaagt
     6841 attagttcaa gctagtattt tatcaattat tatgtctttg attggaatag gatgctcaat
     6901 gttattgaga gattttaagc aattttctct tatatatctt gtggttgctg tattcataac
     6961 tacacctata tttctatctg caaatacatc ttttgaaata gattggatta aatatcatcc
     7021 cttctatcat gtttatagtc agcttaaaaa tgcgtttttc atgaattttt caaaagaatt
     7081 agtttatttt gtagtgtgtt ctttgacaat aatagttcta tttttacttg taaaatatat
     7141 ttttaataaa gagttggtta gggagggata atcttgatag gattacgtta ccagttaaag
     7201 agtataaaaa aagataaaat gtgtataatt tccttctttt taccagttgt tatggcgatt
     7261 ttaataaatt ttatgggaac aattgatata tcttcattag gagagatacg ttttggtata
     7321 gtgaaggata cacttcctgt acaaacagag cagtggttga agaagtatgg tatggtaagt
     7381 gtatatgaca caaaaatgca tttaatacgt gaaattaagg atattaaaac ggacacaatt
     7441 ggagttgtta gagatggtaa aggaataaaa actatgcttt atggaaatga gattaatgct
     7501 ataaaaaatg ttggaaagac attgccagag atgtttagac taaagggtga tttaaaagat
     7561 gttgaggtta caatattgcc taaagatagt attttaaaag agtttcagaa tgtttttatt
     7621 gctatgattt taattactgc tatgtttatg ggatgtacct ttaatgcaat gaatattata
     7681 tctgaaaaag aagatggaat atcatttata aatgaagttt tgccacagag tagaagtcag
     7741 tatattatac aaaaagtatt tttgggtctt ttatgtgggt gtttatcttc aatgataact
     7801 gtatttatat gtttggatat ttcaatatta gatatgataa tgatgttgtt actcgttgta
     7861 ttttcagcat ttatttcatc acttataggt ttatttattg gaaagttgtc agaaggtctt
     7921 atggtaggaa ttgtttatat taaaatagta atgattttat ttataggtgc tcctttgtta
     7981 atatatcttc taggggttaa taccagcggt atagggaatt tatgctatat aatgccatca
     8041 gttgctacat ttaatggtat tatggagatt attaatggta atgttattat tataaaagat
     8101 attgtaattt tggttgtaca ttgtgtagta tggtttatga tatatattat tttagataaa
     8161 aaaagaaagt tatcttttag tagataactc agtataatta taattgggac aatttaatag
     8221 gtgatttaat atactttgta tagtgtaatt tatgtagtgc aatttgtata ctttaattta
     8281 tgtagtgtaa tagttagttt tattttataa ttattcaata taatttagta agaaattcag
     8341 tacaattaga gctacttagt ggaaaactta ataggtactt aaactatata aatactttat
     8401 tttcctccat ttgtactata aatttaattt atgatataaa tggaggtatt attatatgag
     8461 gtattattat ataaagttaa taaagatagt atcaaaatat tatttgctat aaagagaggg
     8521 actcaaaata aagataaacc tatttttcaa tgttgaaatg ataaaatata tttgatttca
     8581 tataaaaaat tttcttcata aattaaaaag tccattttaa gccccctcat ttttaaccag
     8641 ataaatcgag ttaaactatt taaatatatt actcggattc atttgactta gatattcctt
     8701 gcttgtaaaa ttgttttgaa taggggatag ccaaagcaaa aaataaaagt ataatccctg
     8761 ctacgattat taaattatta atagaaatta catctgccat tggtccgaaa atcatcatac
     8821 caagaggaat aaaaccagta tatataataa taggtaagct aagaactcga cctagcattt
     8881 gtggtgctac atgctcttgc aacatagtca tagctgatgc ttgaataatt ggaattgaaa
     8941 aattcgtaaa aaacataaat ataaaaaatt gccaagcttg tgttacaaga cctagaataa
     9001 ttgaaaaaat agcataggat aatattgcta gaaaaaaggt cttatttcta tttttaaaac
     9061 caccaaaaac tcctataatc aatccaccta aaaccataac taaaaatcca atcatttcaa
     9121 taatagacag gtatatataa cccttgccaa atgttcgttc aataagaagt cctataagaa
     9181 atcctgatgg aacacaaaga agcatgaatg ctccataagt gaaaagcact tttctaatga
     9241 acttatctga aaaacagtac tttatccctg ataccatatc tgcaaaaaat gagacttttt
     9301 cagtttgttt tggtatatta tgtttaggaa ttttgatgaa tatcaataat acaatagcaa
     9361 taattgcagt aaatacatca attaaaagaa cttgatttat tttattacca aatccaagta
     9421 ttgcagcagc tacaataggc actataaatt gtactataga ctgtagacta ctatttatac
     9481 cattaaaacg cattaaatgt tcttctggta caagttgagg aatcattgcg tttacagcag
     9541 gtgtttgtac accacttcct agtgaacgta taacagatat tactgatatg gctattaatt
     9601 cacttgttgt gccatttgat gacatcataa atagaattag aactaatgta gatatagcaa
     9661 ttgttgaatc tgatacaatt atgagtacct ttcgattgta gtagtctgcc catacaccag
     9721 caaaaaaaga aattatcatt tgaggtataa aggagcatac agttaaaact gttacccata
     9781 cacctgatga tgtctgaagt gtgacatacc atatcattgc catttgtaca agtgatgagc
     9841 caaataagga aatatattga cttgctaaaa aaagaatgac ttttttcttc catgtagaat
     9901 tagtattttt gttttccatc ctattcctcc tttgatttgt gtgttgaatt tttcttgctc
     9961 ttaaggataa cacacaaatc aaagtctgga gttagagtgg agggctagga aaattgtttt
    10021 ttcataattt gaagatgaga tttcatggtt tttgcattat gttcagcttc tttcaatgaa
    10081 gttatcagtt tgtcacacac tgagataatt tcgtcatcat cttttggagt gtcaaggaca
    10141 gttttaatat tagtattagg attagaagat aaagcattta acattcgtaa aatagctgaa
    10201 agagaatagt ttgcacaacg aagtgcgctt ataattttaa gtcgttttat atcttcatca
    10261 gtatatacac gataaccatt ttgttttctt tttactttta acaaaccatt catttcccaa
    10321 tttcttaaag tatctattgt aacatttaag tgttctgcag tttcttttct agttaaaaag
    10381 agtttatttg tttctggagt atttccattt aaaatctgtg caacaatagt aagtgcttcc
    10441 tcggcattag atttttctat ttctaattgt tgcaagtatt gatttacaag actaatagcc
    10501 ttatcaaagt ccctattcgc tgatgttctt acaatctcaa gggcatcttt tcttaatccc
    10561 ctttgtacca cttcaatttt caaggctgta cgagcaaatc taaattgttc tatatgaaaa
    10621 tcattaaaga tacgataacc attggtatta cgcttaggtt taggtattaa gtttagttct
    10681 tcatataaac gtactgtatt aggatgtaca ccaattaaat ctgctacctc tgatgtcgtg
    10741 taagtgtcca ttagtattca actcctttta gatatatagt attagtcata ataacaccaa
    10801 acaaaagtct ggtgttatag tggagggttt ggttatctaa gagtaattag tttatctaag
    10861 agtgattaat ctattataga agtaagtata tatttttcaa taaactccca tctatcacga
    10921 ggtttaaaca ctattttaga tggtatggct attactaagt catattgtgg aatacaacaa
    10981 atagcatttc ctccagttcc cattgctgaa taccacaaaa caccatcttt tttacatatc
    11041 caccacagat aaccgtattc attactattc attttaaccg attcttcaat ccacgattta
    11101 gatataatac gtttattatt ccaaatacca tcatttaaat acagaaaacc aaatcgcaac
    11161 atatctctag cactcaatgt aagtccccag ccacctatag aataaccctg tctatctttt
    11221 gcccaaccct taagattttt tccaaagaaa tcttcaaaac caaaatcttt catatcataa
    11281 tctggtataa ctttcatacc aataggttta aataagtact cattagcaaa ttcacgagca
    11341 gattttccag tagtttttgt tataatagct gaaagtaggt gcgttccagc tgaagaatat
    11401 ttgaaagtac caatttcgcc tttttgacca agttgattca aggtatattt tatccaatct
    11461 ttttgtttgc aaagtctttc taaagactca gtcatatttt taaaagggta tggtgcagtc
    11521 attgtaagta ggtgacgtat agttactgct tttttacata tttcagaagg actacaagta
    11581 tattcaggga aaaaatcaac aaccttttgg tcaacatctt ttatatatcc tttatctatt
    11641 gcaataccta ttaaggctga tataatactt tttgtaactg atgcaacatg aaaagtatca
    11701 tcagcattat atccattata gtacttttca aagacaactt ttccttttct tgcaataatt
    11761 attccattta tattactata ttgtgagatt attaaaggtt ccagttgtga gagcttttct
    11821 gaactcatgc caacacttga agggtctact ttttcaaata ttaaatctaa gcaattgttt
    11881 ttattcatta aagatacctc cctgttatag attttggatt ttcttttaga gtttttggag
    11941 aaccttctgc aattatataa cctcctttgt caccaccttc tggaccaagc tcaacaatcc
    12001 agtcacaaac atttaataca tctatatcat gttcaacaac aattacagaa tttccatttt
    12061 ccaccaattc atctaataat tgaatcaact tagaagtatc atatagactt agaccagtag
    12121 ttggctcatc caatacataa aggatattac catttcgttt tttaccaatt tcttttgcaa
    12181 gtttgattct ttgggattca ccaccactta aagtcggtgt aggttggcct aattttatat
    12241 accccatacc tatttgttct aatacattta agtgtgaaac aatatttgga atatccttga
    12301 agaaatgtac agattcagaa acactcatat ttaaaatatc atgtatattt ttatttttat
    12361 atttaataga taaagattca tcattaaatc tttttccctg acattcactg catatatggt
    12421 ctatacttag attatttcct aaccagacct tttcatatcc actaccacta catttaggac
    12481 aagcaccttt ggagttaaat gagaaatgac cagctgtaaa tcctcgttct aacgattctg
    12541 gctgacctgc aaatagtgta cgtatcttat cccatatacc aatataagaa gcaggagttg
    12601 agttcatatt tttgccaata ggagattgag atatctctga atatccagaa atatgtttag
    12661 taccaatcag tctatctgca atagtttcaa taactgcata atcgtcttca tcacctattt
    12721 cgctatctga agaatttatt tgattattga tagtatggtt attaaattgg cttctaagaa
    12781 gaggaagtag ggtgtctgat ataagtgaac tcttgccact acctgatttt ccagatattc
    12841 caaccatagc acccaaaggt aatgatacag ttacattttt aagattattt gtatttgcat
    12901 tttgaatagt tatacaaggt attttatcag tatgtgtaat atttttattg cttgttctat
    12961 taggcattgg atattttcca gatagatact gcccagtaag tgatttgtcg gattgaagta
    13021 gaccttctaa atctccttga tatactaatt gaccaccttc aacaccagct tttggaccaa
    13081 tatcaataat atgttctgcc atttcaattg tgtttttatc gtgctcaact actatgaccg
    13141 tattgcctaa atctttaagt ttctttattg attttaagat gtctattttt tctgattcat
    13201 gcaatccagc tgttggttca tcaagcacat aaattaatga gtccatctct gaatcgagat
    13261 gtgaatttaa aaatagtctt tgcatttccc caccactcaa agttgacatt tctcggtata
    13321 aggatagatg acctaatcgt gattctatta aatgtcgagt tttggataaa atatcattta
    13381 caagatttgt accaaatgtg tttaaattac cttggtttat taagatttta aggaaatcat
    13441 caatttctaa aatcgtcatt tttccaagtt ctccaatatg ttttccgttt aaaagtactc
    13501 tacgtgcttc ttcaccaatt ttaaaaccat tgcaatctga acaggcagtc atagtataaa
    13561 ctccatttaa atcctcaccc cttttgtaac gattgtgaaa tacctttgat aaagaggaac
    13621 tttttttacc attttcataa tgaccataga gtacttcatt tcttatttct tcaggtagtt
    13681 gtaagaattg tatgtctaaa taatcgttga attttttaga aaatactctc aaatatcctg
    13741 gtgtaatctt tgctctatct aagacttgtt ttagggtatc atgcttatca aggactaatt
    13801 tttcaatatt aatctcaaaa tatgcaccat gtccagagca cttcatacac attccatctg
    13861 aagagttgta tgagaaataa cttggtctta atcgttcttc ctcataccca caattattgc
    13921 aaattagatt atcgcttaca ggagtatcac acatagtaca cattatttga ccttctactg
    13981 aatacaatag tgcaagcatg ttgagaatat tggttcttgt gcctactgtt gaacgaggat
    14041 tgctctggcg aataatattt tgttgaacag ctatagtggg agctaaacct tgaatattat
    14101 caaacttatc ctcactatca atacctgcaa gtatacctaa agattgcaga tattgtttac
    14161 gaccttcctc aaatacaatg tcaaacataa ggctagactt acctgagcca ctgacacctg
    14221 ttgcaacaac aagcttatct ttggggatag aaacatctat atttttaaga ttgtgtatct
    14281 ttgctccatt aatttttatt tctttcattg gttcacctca ttttatcaat tttatcaaac
    14341 cgtaaaatag ggatatatta atccttaata caagaataga ttaggtgagg ttattaaaaa
    14401 ggttctatag gtaaatatat atcgacaaag tgtctatttt gagggtgatt gtgtgggttg
    14461 ttaagatata cttcaaaagg gaaggaggca cgtagcttat aattaccatt tgatagccat
    14521 tcattataca taaaatccca cgcatcacta tattcagatt ttgaaatatc aaaatgtccc
    14581 acaagatatt ttccagaagg gattatcata ttgccaagat tgtcattctc tttgacaaca
    14641 atgttatctg gaatggtcat gcaaatacta gtccttaatt gatgctcctg tgtaaattgt
    14701 ggattatcat gataaatggc taatatttgt gtgttttcaa gtccaagtag attctgctca
    14761 cttgcatatg tgaataaccg ttctaaaagt tttgggaaag tactggttag attaccatat
    14821 gaaccagtat atctagtgta aatagtattc atattatcaa gttctagaat ttcaatttca
    14881 cctttaacct ctctagtatt cttacattta ggttttgata tgcttctatt gtactgagaa
    14941 attttatatg gttctttgca attcttgcta taattgtttc tatattttat agggcttatt
    15001 ttatagtaat ttttaaatgc tctcgagaaa actgctgaat cagtaaagcc gaagtagtgt
    15061 gcaatatcag taacagtcat gtcagttcga tgaataagaa aagcagttgc attttctagt
    15121 tttagcctat ttacatattg tgccaaagtt tctttttcta ttgctttgaa gattctatga
    15181 aaatgaaatt ttgaaaaacc tgctatatta gaaagttcat caagagaaag aggttcatgt
    15241 aaatgttctt ctatatagtc ttgcactttg caaatacgat ttagatattc ttttttactt
    15301 ttagcatttg tcatatatag ccctccttat tgtgtaaaat gtgtattaat taatttatag
    15361 caatatagta ataaaatttt atgtttttgc aatttatgat aaataagata gcgtttaatt
    15421 ttttataatt gataaaagat atttataatt aataaaagat ataagatgcc ttatatttat
    15481 ttttgcatat aagtatagtc ttcgtaataa ttagtatacc atagtgattt atttttaatt
    15541 gtgtatttat ataaatacac aacttatgat atggacgaat tattatgcaa ataagctgta
    15601 attaaataaa ttgcaatata aaccagttga aacataagtt agggaaatat tatcaaagtt
    15661 attatttagc ataagagtat agagggaata aaataagatt aaaaaattac atactaaatt
    15721 taataaaatt attatattaa aaataatatt aagtttattg tttaaataaa aaagttaaat
    15781 ctacactatt aacttattat acttaaaact ttaaaatgaa aatatcaaag aatacttttt
    15841 aataaaaata atcatttaat aagttattta aaaatctaaa aactttacaa caaattatct
    15901 atttaaattg gaggagtggg aatatgagta atagttttta tcaattaaat tcagcagtat
    15961 tatattttaa tgaaaaaaga gatgtaaata gaataaggtt taatcactat gtaatgagaa
    16021 aagaaaatat acaaagatta aaaggaactc tgccaagagg acaatttatg atgacagtaa
    16081 ggaaagctgc atctgacctt gatgtatcta tatctacaat aagtagactt gtaaatgaat
    16141 ttatagattt aggtatattg agattaataa gtaggggagt aaagggaaat tgttgttctg
    16201 tatatagtta tgtttgttct gaaaatagta atgcagaaat tgtaacaaag aatagtgata
    16261 ttttcaaaaa tatagagaaa tacattgatg caactattaa caataaccaa aaaacaatga
    16321 aatataaaca tagagatgag ttgttcaaga acagtaatac caacacatac agccgtataa
    16381 atcaagagag tatagacaaa gattatgatt tgataattca tactgggtat gaaacagaaa
    16441 atgagacaaa gaaaaaagaa ttattaaaaa ataatttaaa taaaaagaat ttaaataaaa
    16501 atacctttga aaatttggat gaagatttga ctgaagattc tacttataaa aatccagaaa
    16561 gcatacatga aattattata agaaaattaa atagtgaatc aggaaaaaat tttaaagctg
    16621 atttgagtat aactaaggca cttatagata aaagattaaa agaagggtat agtttagaag
    16681 atttttacaa ggttatagag gcaaaggtaa gaagatggag atatacagat atggaaatat
    16741 atatagaacc aacaattctg tttgggtatg aatttgagtc gtatttaaat gaggagagtt
    16801 ctttatctgc ttgtaattat ggtgatatgt gttatgaaga tatgtattga gatattagtt
    16861 gctttttagt tgtttaaaat atgtttatat ataaatataa atagtgtatt aaaatggagt
    16921 tgtctcaaaa tagagagaag cctcttctta attgtttaaa tgatgaaaat atatttgatt
    16981 taatacaaag gagagtgcct tatgagctag aaagttcatt ttgagacact cactttttta
    17041 atatactgga gaaatataac ccattttaat ggcttttgta atagcctcaa ctgatgatga
    17101 aacatctagc ttgtcatata tgtgttgtaa atgatttgat aatgttcttt cacttatata
    17161 caattcatca gcaattattt ttcttttttt accactacag ataagctgta aaattctttt
    17221 ctccatatta gttaaatctt caataattac ttcagtattt tcagatggaa aacaggttac
    17281 cccttgatag acttttaata atgaatcaat taaactatca gggctaatat tcttatttag
    17341 gaatccatag atacctattt ttttagcctc atgtttataa actgggaggt cgtatccagt
    17401 caagattatt attttaatag ttgaattagt ctctaataaa ttataagcta cttttaagcc
    17461 atcacattca cttaagcctc taaggtttat atccattaag acaatgtcta tttttttatc
    17521 ttgaatcatt tctgaaagat tatggatgtc ctgtgtggaa taaaactgtt cgatttcttc
    17581 gtattcttct agtgcaattg acaagctttt agcaaaaagc atatggtcat caactaacaa
    17641 aatatttata agaaccatct cctttcatag ggattgtaat ctgtacacaa actccatgag
    17701 gtatattatc agaaatactt atcgttcctc ctagattttc tacttgttct ttaattgata
    17761 taatcccttt gtgttttatt atatcaaaag taattttagt tatatctaaa ggtgttttaa
    17821 aagatgtatt tttcacacca ttatcattaa tatttaattt tattatattt ttttctagtg
    17881 ctaaagctat ccatgcatgg ctaccatttg aatgtttata cacgtttgtc aataattctt
    17941 taatcagtcg atatatcaat atatcatatg gttcaactaa gaataaagta tcagaacact
    18001 taaatgaaac acaaatgttt ttttgtggaa aggatgaaga aacactttca attaaattct
    18061 gataattttc ttttactgtt aaatttttta aaataacagg atgatagtct tgcatttgat
    18121 ttcttataca tgtatttaga ttgttaagtg tttcatatat aatatcttga acttctgggc
    18181 gatatgactt actcatcatg ttttttattg aaagcaggtt ctgtaatatg tcatcatgta
    18241 aaaaattaga aaactctgtt tttagttgtt cttcttgttg taatttttct aatgcaaaag
    18301 tatacttgct atttttaact actttatttt tttcatctct aaggttaaac tccaaaataa
    18361 tgttacagag gaaaataagc ataaataaaa catttatagc tattaatatt atagaaaaat
    18421 tcccattggc aaatagtacg accaagctaa ttactaaaat acttataaaa agaaatatag
    18481 ccctttgttt tatgttaaaa actgttgaaa taggaaaact atcattttct ttaagtgcaa
    18541 taccatgaat actcataaaa aataccaata cagttagata gattccaaaa ttaccaatat
    18601 gatttgatat tcttagtgta aaaaaataat aagtaaggaa tcctataatt gttataaata
    18661 ctgaaatcga tataggcttt ttttcgcttt ttatgacaaa aacaaccctt ttcaaatgat
    18721 aaaaaataat atataaaaag cttattatac taacaacaaa ctgtattccg tacatacaag
    18781 catacgttct gttagaaata aatgctccta caattgcacc aatgcaggtg ataagcaata
    18841 aaatatctgt tatcttacgg aaattgtatc cactaccttg aaacaaaaat aaaaatataa
    18901 atttaataga gacatacact ataactgtgc ttaatatttt aaaaataata gtgcctattg
    18961 gtgtggttac aaatgataag agtaaatacc aactgtctag tgctagtaat ccacaaaata
    19021 atgaaataat gttattttct cggacattac aagaggttat atatgtgatg tctatgagta
    19081 ataatgttga aattattaag ggaataatgc tttggatatt catataagtt tcagtgcttg
    19141 tagatattcc catgaagaga agtgatagaa tgtagtttcc taaaaatagt atttttaaat
    19201 taaaatttgt caatcttata cacctcctta tgagttaatt atattaattt tatgactaaa
    19261 tcaaacctaa gaatctataa ttttaaatta tatcaaatac ttataaatga agtataccaa
    19321 atcgtcacac ctctaagctt gacgatttgg taaatattaa ttttttaata caattttaca
    19381 acaggattta atagtaagta tataatatat caaatacact acagaagtta agaaaattgc
    19441 aataatcaca ggtatgtatt gtgaaaatga atttccaagt aaattctgca tcaaagcagt
    19501 cttataaacc aaggtagcaa atatacagtc caatatacca agtaaaaacg gaatattaaa
    19561 aaatggcaat acttgttttt taataatttt tttaatttgt atattatcat aacccatttt
    19621 ctgtaaaatc ttataatcag atgttgaatc tgaaattgct gatatattgt taaagtataa
    19681 aatacttcca acagcaataa agaataatac cacaagaaat ccgattaaca gaaatgtaga
    19741 actattaatt gataataaat catttatcct gtgagaatat ccttgtaaat aagggcttcc
    19801 atctaaataa tctgaaatat tactatataa attttcatta tttttaattg atttaccatt
    19861 aatacttaaa atgcttgtca ttggtaattt attttgtgct atttgctcat atatactatc
    19921 attaacgata agtgttccaa cgctattggc aaaagaaata gcattgttta atgatgtttc
    19981 ccttacagct acaggtgttt ctttaccatt aataagtaat ggataaatcg ttccattttc
    20041 actatatcca tcattatttg gttgatattt cattaaaata cattcattat cccttaaagg
    20101 ggtaagttgt tttagtagct ttgttcgatt ttgtgccttt aataaagtat aataatcaga
    20161 aaaagatata cattcaaatc ctgattctct tgaaataact tctttagaag aactactatt
    20221 agataaatta ttcttagatg taccaatttc atattcaaat ggaaggtctt ttgatgaaga
    20281 ttttacctta taaatatttg tctgtgtaaa aataatatca tctgtattag acgtatattg
    20341 actgacaatt tgttttacat cttctatttg tttatttttt tctactctaa attctatctc
    20401 tgaaggtgca atacgcgaaa cagatgcaat agggtagtat aaggacagtg ccataacact
    20461 tgaaactgtc aaagtagtag cagagagtaa tgtaagcata attagagttt tagagtttga
    20521 acgtatacga tagataaagt ttggaatagc tattatcttc atatctgtgt agaaagtacg
    20581 tttatttttt ttactctttt gcataatata tggaagaaag gaattgataa agagaactgt
    20641 accaattaca atgataatca tagttatcaa gcccatttga taaaatccaa tacttaccca
    20701 tactgattta gctccacgaa gaatatctag tgataaacaa tacccactta aaatcataat
    20761 aaatcccata aaggctggaa tttttctgaa ctttaatttt ttttctgcac ttttttcatg
    20821 tcttatcaat tttacaagtg aagtcttata aagaaattta ccatttgata tagctaagac
    20881 taaaacaact aatgctataa agataattgt tttgtttatt gcatttatat taaaaaatgg
    20941 tatctgtgaa ttatcaattg ataaattaag tagtgctgta attccaaaga caataccctt
    21001 atgtgacaat gctcctaata ccaatccagt aataaaagct ccactacaaa ttaatacatt
    21061 ttcaaaggta agtagcgata atattgtaaa cttacgatag ccaagtaaag catatatgcc
    21121 taattctttt gtacgacgtc tcaagaagaa tcgatttgag tatgccatat agaagatgac
    21181 aaatgccatc aaaaatatcg aaataacatt acacatagat tcaactctac catcagttga
    21241 aattttttct agcattatct tattaacaga gaatgaagta aatgcgaaaa atacagtaat
    21301 aacaaaagag actgaaagta gatatagaga atagaatgaa aagttttttt taagattctt
    21361 tattgccata taaaaaatgt tcattaaatt atcctcctat cttttagtat ccaattttgc
    21421 aatttcttga ataatcaact cataaaatgt atgtctatta ttcggttgtt tatttaattc
    21481 tttaatgata tgaccatctt taaaaatcaa aattctattt gcaaaacttg ctgcataggc
    21541 atcatgtgtt accattaaaa ttgttgtttt caactcctca tttgcttcct gtagtgagtg
    21601 gagtagttca gtagctgaat tagaatccaa agctcctgtt ggttcatctg caaagagaat
    21661 actaggatgt tttactattg ctctaactgc tgaagctctc tgcctttgcc caccagataa
    21721 ttcatttggg tatttattta attgagaagc tatgtcaaat cgttcagcta gactctttac
    21781 catgttttct attttatctg gattgagttt ctgaagtgta agaggtactg aaatattctc
    21841 gaaaattgta agactatcta gtaaaaaata ctcttgaaag ataaagccta aattatcctt
    21901 acgaaaatca gcagcacaag tgtcattaag cgatttcaaa tttatattat ttatgaaaat
    21961 atctccactt gttggtttat caattgtaga taatacatta agcagagttg ttttcccaga
    22021 gccagaagct cccattatac ctataaattc accttctgat acattaaagg ataccttatc
    22081 taaactcggc tgttgccctt tattataagt tttagttatg ttatttactt ttaatattgt
    22141 attcattgta tatgtctcct ttcgtcttaa tatagtcaaa ttatatatta accttattgt
    22201 ttcttcatga gtaaatcacg caataattct acacaaatta cttatatcac aatatattgt
    22261 ttaaaatcta actttattag gtttgggatg atggacaaga ttttaattta aaagagtgca
    22321 tagatatata atggcataat gtagatttaa attaaaaaaa ataaaataaa gccataaata
    22381 ttgaaaaatt caatatttat ggctttattg cttgtaataa ttaatagaat atatattttt
    22441 tattaatcat ctatttcaaa ttctaatatt ttaccagtaa ttgcattaat tgttatctca
    22501 tattcaattt ttccttttat tatttcacct tcatattctt tgtcatcttc atcatactta
    22561 aattttacta ttttcccacc aggcacttta tctagcatta ttgatttagc tttttcagca
    22621 ctaataatag aactgttgtc attagtatta gagttattct tatcattatc atcaaagtca
    22681 tcatcagaat cattgtccat gtcaatatct acaattcttc catcaaatgc acttatctct
    22741 aattcatatg ttttcttatt ttttattact ttagcctcat attcgttatc ttcagcatca
    22801 tatttacaat agattaaatt accattagga acagcatcta atgctataga cttagcttta
    22861 tccaatgata tattttgtgt acctaaatta ttatcattta agtcatcatc tttttcaatt
    22921 tctattattt taccagagta ggcatcaatt tctatctcat ataggatatt atcctttata
    22981 actttgcagt catattcatt atcatcttca tcataataac aaactaaaat atcgcttcct
    23041 ggaagagctt gttttaatat ttctttagcc tgtattaaag atattttttt agttttattt
    23101 cttatgttca cattttttag ttttaaaata tcttcaaatg ctttttgatt atatcctcct
    23161 cctacttgtg ttatttcatc tatatcttta tttttaataa attccttttg actatttaca
    23221 aggctaccat tagatatcat tataggagaa ttttctttag cagctaatac tcctattgat
    23281 aatgaatcta ctaatgcatt ttcttggtta ataccatctt tagctacaaa tacattattt
    23341 atttttttat ctttataaaa tttatcaata atttttgcat tagtattgtt tctatctgaa
    23401 ccactgattc tttctctgtt tggatatttc tttactgtat tgtctgataa aatcttattt
    23461 cctccaacta tgtaagattt ttttatagac ctattgttta agaaatttat actactatca
    23521 ttgctgtttt catctgatac taatattata ggcatattat gtattgctgc tggagaagct
    23581 atactaactg catcagataa tccctttagt ccatttacaa ctgcaacatt ttctaccttt
    23641 tttatcttat ctatttcttt aagtacattt gtagacattt tatatatatt gtttcctact
    23701 attttattta tttttatgtt aagtgatttt atttcatttt ctactttaga agaaatgcta
    23761 tttccactat ctacaatgta cacattatct acaccaagcc ttttaagctc agccttagtt
    23821 gaattttcaa tactgttgtt gtttactaaa agtataggtg cattctttag cttagcaaat
    23881 ggatttgcac aaagcgcact ttgaatagaa ttaccattaa ctataatggc tgtttttgat
    23941 tgaacccatc ccaatttact tacttctact gctgtttcat atcttgtttt acctattaat
    24001 ctttcttgct ttgtagtatt gtctgcaaaa attgctgaag aactagaaaa aaacatcata
    24061 cctgatatta atatagctaa atttttatta ttcatatttt tacctcacaa tctttaaaaa
    24121 tttgttattt agcatactta ataaaatata atcttaaaat caaattgata ctgagtttga
    24181 agttacaaaa tcaacaaata agatttcttt aatacaaaat tttccttttt atatttaaca
    24241 ttgtatcaca aatataaaaa ggaaaaaact ttttaaaaag ggtatacact attcattttt
    24301 tatcttataa ataagtcttt accactgttt tatatatttt aaaatagaca caagacctat
    24361 ttctaaatct tttataaata ttttaggtga aatttctttt taaacatatc taaaaagtat
    24421 ttgtagtaat attaatggac tgaatttctt aaagtatata tttctttgca tgttggagtt
    24481 tgtgaagttt gagaattgga gggtgaaaga aacatgcaat ggattaatat taaagaactg
    24541 tatttttata atatttgtct taaaaataaa aaaatctatt gacttgaagt taactccaag
    24601 tagtaaagta taattataca agaattatat acttgtaaga atagttaaag tagagagaaa
    24661 aaacaaacaa gttttaaagg gggaagtaaa acaatggagg caaaaaaatt aggatttgga
    24721 ttaatgcgtt taccaataaa agatgaaaat gatgttacaa ctattgatat ggaacattta
    24781 aataaaatgg tagacacttt tttagaaagg ggatttacat attttgatac agcctatgtg
    24841 tatcacatgg gaaaaagtga gatagcactt agagaatctc tagtaaaaag acacaaaaga
    24901 gagagtttta ctatagctac aaaacttcca ttaatggctt taaagaaaaa agaagagcaa
    24961 gaaaccattt ttaatgagca attagaaaaa tgtggtgtag actattttga ctactatctt
    25021 ttacacaata taggcgtgtc acattatgaa gtagctaaaa aatttgatag ctttaagttt
    25081 attgaagaaa agaaaaaaga aggaaaaata aagaatattg gtttttcttt tcatgatagt
    25141 gcagaactat tggataaagt cttgagtgag catccagaag tagacttcgt gcaattacag
    25201 attaattatt tagattggga taatgaaagc atacaatcta gaaaatgcta cgaggtggca
    25261 gagaagcata ataagcctgt aattgttatg gagccagtaa aaggaggtac acttgcaaag
    25321 ataccagaaa aagcagagaa attattgaat gactacaatc cagatatgtc aatttcatct
    25381 tgggcaatac gttttgcagc aagtaaagat aatgttatga tggtcttaag tgggatgtca
    25441 aatatggaac aattattaga caatacagga tatatgcaaa atttcaaacc attcgtacaa
    25501 gaggaatata atattataga tgaagcagta gagattatca acgaatcaat tttagttcct
    25561 tgtactgcct gtcagtattg tgtagaaggc tgtccaaaaa atatcgctat tccaaactat
    25621 tttgcgctgt acaatgcaga aaaacaagct cttaatactg gattttcaac acagatggtt
    25681 tactataata attatactaa aacttatgga aaggcctcag attgtattga atgtaaacaa
    25741 tgtgaagaaa gctgtcctca acacattaaa attatagatg ctttaaagaa tgtagcagaa
    25801 acctttgaga aataattcaa tctatacaat atcaagagga gaagatatgt atgacgattt
    25861 cagaagttag taaaaaatac gagctttcag cggatacttt acgatattat gaacgaattg
    25921 gtttaatacc acctgtaaat agaaataaaa gtggaattag gtcttttaca gaagaagatt
    25981 gtgagtgggt taatttcata aagtgtatga gaggtgcagg tctttctatt gagacattaa
    26041 ttgagtatgt agctatgttt caacaaggga gcagtactat caaagctaga aaagaacttt
    26101 taatagagca gagaaaccaa ctagcaaaaa gaatagaaga aatgcaaaaa actttggaac
    26161 gattaaattt taagattgat agatatgaag aaggtattat tgagaaagaa aaagtattaa
    26221 agagcagtag aaataagaaa atggaggcag tatcttatga gtaaaaatgt attaatagta
    26281 tcagctagtc ctagaaaagg tggaaattct gacttattgt gtgaccagtt tatacaaggg
    26341 gtattagaat ctaaaaatca agtggagaag atatttttaa aagataaaga tattaactat
    26401 tgtactggat gtggtgcttg ttatgaaaaa gaagcaagtt gttcacagac agatgacatg
    26461 ggagaaattc ttgaaaaaat gattggggca gatgtgattg ttttagcgac tcccgtttat
    26521 ttttatacta tgaatgcgca aatgaaaact atgattgata gaacttgctc tagatatact
    26581 gaaatttgtg ataaagattt ctattttatc gttgcagcag cagatgaaaa tgtggctgat
    26641 atggaaagaa caatagaagg atttagagga tttacatcat gtctaaatgg ttctaaagaa
    26701 aaaggtatag tatatggtgt aggtgcttgg aatgtaggtg atattaaggg aagtaaggca
    26761 atgaaacagg catatgaaat gggtaagttg gcttagtatg tttgtataaa attgtataaa
    26821 atcgaatata ttcttatcat ttcaacaata aaaagaggct tatctatatt ttgagacagc
    26881 ctctttgtgc tatatcattt atttttattc tatatcctta ttataccctt tattttttta
    26941 tgcctattta agtatctgtt gttactcata tattttaata attaccctta aaaaactata
    27001 cagattcctg cataatatta ttttctttag taattaattt ttctaggttt ttccaatcca
    27061 tttcttccat atttgcaaaa taatgaccac ttcctatgca agtcagataa gactttccat
    27121 ctaaatcaaa cgaagaacct ccaatacact ttgaattaca tttcttacaa gtacgagttt
    27181 tagttatact atctttaata gttttagagc attcctccac agcatcttta tatgtattta
    27241 gatgaaaaag atttgcttta actctccatt ttttttcatt acattcaata gtaaataagc
    27301 tacgttttgg tttcttagtt gaatatacta ttttgtaaga acgagcacct gtttttggtt
    27361 caattttaca atctaatgat ttaccaagtt catgtaaatg acatgcaata tcataatctt
    27421 taccacttag tacttctaac atttcttctg ttgtttctgc cgttaattca cttttgctca
    27481 tattaaaaaa atccccctat ataagtaata atttcacatg aaaataatta atataagtat
    27541 attaaataaa actattaaaa tcaataaaat tactacaatc ttacattatt gggcatagaa
    27601 tgagagctaa tgatttatta gaaataagac ttaatagtat gaaaatttac ttagacgtgg
    27661 tacaattcta taaaagattt aaaactagga aaggagaaag ttgttgagat acggccaata
    27721 taacaattta tttataagtt gtaaatttat tatgagatta attagattgt taagtaatac
    27781 tatcaaaagg tagttttttg gattttcagc aacagtggta gatattgata attttttggt
    27841 tattattata tttagctgtt atattttcaa taggctctat gataactagg gtaaataagg
    27901 tatgggtaaa ggttttatta tttataatag tgggattgtc aactatagtt ctttcatatg
    27961 taataacttg ataatttaag attgaaaaat aactttaatc tgtaaattct caaaacaaga
    28021 attctcatgt tggtaaattt ctagatatga gaaaaaaatt gacatcataa aaaagtaatt
    28081 ttaaagcatt tttttacgaa aaaattcaga agtaactatt ttgaatgact tcacaaaatt
    28141 ttatatataa ataaagtttg gcacgttaat tgctttaata aaagttaaca agacacaaat
    28201 aaacataatc atctaagtat tgattatttg aagttttaga tttgaaattt aatctaaagg
    28261 ttcgtattaa tattggtgtt taggaaattt tattttcctg taaatataac ttaataatag
    28321 gaggtgaagt catgtcaaaa gtagtaatag ctacagagaa agctccagga gcaattggac
    28381 catattctca agcaattcaa gttggaaaca tagtttctac atcaggtcaa cttccaatag
    28441 atatgaagac tggcgagtta gtatctgacc caaaagaagc aacaaaagct tctttagata
    28501 atgtaaaagc aatattagaa caagctggta caagtatgga taaaatattt aagactacag
    28561 tattcgtaaa agatttaaag gattttaatg atattaatga agtatatgct acatatttta
    28621 aagaaaatcc accagcaagg tcatgcgtac aagttgctca attaccaaaa gatgcagttt
    28681 tagaaattga agcaatggca gtattataag tattataaca ataaaaccaa taacaaaact
    28741 aataaaaatt aaaaactaat aaaaaaagtc tacaattaaa aaagtttata ttaaaaaagt
    28801 ctatataaaa atctatctaa atatttaact attgagcttt tctcatataa tgtatatttt
    28861 tatgtcaaaa atatatttgt tatatgagga aagctttttt tattttatta ttgtattgtg
    28921 atttacttta ttgtctgtat cttataatta agtaattaag gtcatcatat aaaacaaact
    28981 ttttataaat taatattgtg tgttttaatg taaatatata aataagtaat gttttatata
    29041 tattttaaag agtgactata tgttaaaata tagctaaact gataatttgg taaattaaat
    29101 tctaatgggg gaaactatgt taagtaaatt aaaagaattt caacaagaaa tgataaaata
    29161 cactgaaaca gtagctagtg tgttagatgt agatattgaa atagttgatg atagattaat
    29221 aagaattagt ggtacaggtc tgtataaatc aaagataaat gaaagcgttg ttacagaagg
    29281 atttatttac gacaatgtta tacagacagg tcaggaatta gtcgtattgg atatatgtga
    29341 taatcagctt tgtatagaat gttcccatta catgaaatgc ctaaataaag taataatagc
    29401 agttccaata aagtataata atcgaactat aggagtaatt ggtgctatta gtacagataa
    29461 aactaaaaaa gtagaaataa gtgcaaaaat agataattat ttaaaatttg tcaatcatat
    29521 atgcgattta atttctatga aaatagaaga acatgaagcg tcaaaaaata gcagtagaaa
    29581 aatggatatg atgatagaaa tcattgaaaa tgttgaaaaa ggcgttataa tactagacat
    29641 aaatagcaaa atatcttata taaacaatat agctctaaaa aaattagata tatataaaaa
    29701 tataatagaa aatatagtaa atatagtatc tgttgaatct tcctcaaatg gacatgaatt
    29761 actagaaatt gatattgata acaaaattta taatataaat gccaaaataa ttccggtata
    29821 tccatatata aatcaatacg acaaaataat aatatttgac aagacatata tcaatcataa
    29881 aggacatgga aaagtcaata gtggctgggg aaatagtgat atagagtcta taattggaaa
    29941 ttcagaggca atgttaaaag taaaagagag aactaagaaa ttagcaaagt caaattcaac
    30001 tgtacttata actggggaaa gtggtacggg taaagagcta attgctaggg ctatacatgc
    30061 tgaaggtagc agatggaaca agccatttat tgcgataaac tgtgctgcta ttccagaaaa
    30121 tctccttgaa agtgagctat ttggctatat aaaaggtgca tttagtggag ctagtagtgg
    30181 aggtaaagta ggtaaatttg aacttgcaaa tgaaggtgtt atatttcttg atgaaatagg
    30241 agatttgtca atgcctttac aagcaaagtt acttagagtt ttacaagaga gaaaatttgc
    30301 gagaattggg tcaaataaac ttatagattt agatataaga gtgattgctg ctacaaataa
    30361 aaacttattg aaattagtaa atgaaggtaa gtttagggat gatttatact atagattaaa
    30421 tgtaattcct ataaatttgc cacctcttag ggaaagaaag gatgatattg aggcaataat
    30481 gatgaagttt gcttctaaat attctttaga attaggtatt cagttaaata aaatagaaga
    30541 aaatgtaatg aatatgttga ttaactataa ttggccggga aatataaggg aactggaaaa
    30601 tgcagttgaa tatatgatga atttggttgg agatgatgga ataatatata aagatatgct
    30661 tccattggat attttaaatt attataatat taatggaaat gtttgtaaaa ataaggatat
    30721 aaatataata tttgaagatg acatagttgg agggatagta gagaatcagg aaaggatact
    30781 ttcaattaaa gaattagagt tgacttacat aaacaagttg ttgaataagt atggaagaga
    30841 tacaaagacg aagaagaaga tagcaaagga tttaggtata ggtttggcta cactatatag
    30901 aaaattggaa gaggaacagt agtaatataa tattaaaatg ataggtattt gtgtgttttt
    30961 atagataggt atttttactt tatggtggag gtgttattat gcaatatgcg atagagctat
    31021 attatgataa aaaaacggaa aagcaacttt ttgatttatc taaaaaaatc gctgatgaaa
    31081 aaattagtac gaagtactta gaatggaaaa caagacctca tcttactttg gcttgtttca
    31141 atgatgtgga tgaggcttgt tgcatagaca agctaaaggg gtttgcacaa aaccataagg
    31201 taatacctgc ttacattggt tcagtaggca tgtttaatga tactaaaacg gtgtttgtat
    31261 cacctataat gaatagcagt atgtatcagt ttcagagaga attatatgag gtactacaag
    31321 attttgattc aaatggttgg gaatggtacc accccaatcg ttgggtaccc cattgcacaa
    31381 tagcacttac tggagatgat gaaagtgagg ctttttttcg ggcaagtgat gtattactgc
    31441 gtgagttcaa aaaaataagt ggtgagtttg tctcaatagg attggttaaa attacatttc
    31501 ctgtggaaga aatttttaca gtgaatatga ataggtaact ttaactctgt tgtggatgtt
    31561 atgaatattt tgcatagtgc atttcatcag ataaatgcga agttgcgaat ttcgacagct
    31621 caatagtcgc aagtaggaca caatggtaca catattgcac ttttgcttat tggagggacg
    31681 cccatgtaaa cttctgtaag aagctatgaa aagatttaag ccattttgga ggctttgggt
    31741 aataaagaat atttgggtaa taaagaatat aaagtatata aatttataga gtttatgcgt
    31801 aagaaggtta tagccatata tttatagaaa ataaaagtag taatatatct gacaaaacaa
    31861 tagacatata aaaaataaga gcataataaa ggaagaatta aaataaataa acgatttctc
    31921 gaattgataa ttctcgtatt gataaaaatt tcccaatatg agaatttttt cttttataaa
    31981 tcttattttt cacatttaat atttataaaa ttcaaagaaa ttttataaat atatgtaatt
    32041 ccaacataaa aaaattgttt ttagaataaa taatattggc atagtaattg cttcactata
    32101 agacacaaag ataaaaaatt aaaatgacac cgaaaaattt gaaaggggaa tataaaataa
    32161 atgagagaaa taaaatggaa attaaataac ttacctaaat cagaggaaaa agaaaaagga
    32221 attgagtttt taagagatga agaaattgca aaggctaaag cttttcatga gagctttcca
    32281 caatatgaaa aaactccttt agttaaatta gataacttag caaaatcact aggcgtaagc
    32341 ggaatatatg ttaaagacga atcttataga tttggtttaa acgcatttaa agttttaggt
    32401 ggttcttact ctatgggtag atacttagct caaagattag atacagatat atctgagtta
    32461 gggtatgaca aattaacttc aaaagaaata aaagaaaaat taggagaaat aactttcttt
    32521 acagccacag atggaaatca tggtagagga gttgcttgga cagctaataa attaggtcaa
    32581 aaatctgttg tattaatgcc aaaaggttct tctgaattta gattaaataa aatcaaagga
    32641 gaaggtgcag atgctagtat aacagactta aactatgatg atgcagtaag attagctaat
    32701 gattatgcag aagctgatga ccatggagta atggttcaag atacagcatg ggacggatat
    32761 gaagaaatac cagcatggat aatgcaagga tatggaacta tggctaaaga agctatagaa
    32821 caattaaaag aatatggagt agatagacca acacacgtat ttgttcaagc aggagttggt
    32881 tcacttgctg gtgcagttca agggtatgtt gcttcaatat atgatgaatg cccaataaca
    32941 gtagtagtag aggctgatga ggctgattgt tactataaat cagcagaagc tggagatgga
    33001 aaaccaagat ttgttggagg agatatgcca actataatgg cagggcttgc ttgtggagaa
    33061 ccaaacacta taggttttga agtgttaaaa aattattcat cagcattcgt ttcagcacca
    33121 gactgggtat ctgctaaagg tatgagaata ttaggaaacc ctctaagagg agatgagaaa
    33181 gtaatctctg gagaatctgg agcagttaca actggagcat tagtttcaat ccttgaaagt
    33241 gaagatttaa aagacttaag agaagctttg aaactagatg agaactctaa agtattatta
    33301 ataagtacag aaggagatac tgaccctgat aaatatagag atatagtttg gaatggtgaa
    33361 tgccaaagta aataaaagac ttaaggaaaa taaaaactta acaaataaat gaaaaattta
    33421 aggaaaataa aaacttaaat aagtgaaaac tttaaataaa ataaaaacta aaacaaa
//
LOCUS       DAMJWO010000043        33332 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.044, whole genome shotgun sequence.
ACCESSION   DAMJWO010000043 DAMJWO010000000
VERSION     DAMJWO010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33332
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.044"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            157..297
                     /locus_tag="PC366_002088"
     CDS             157..297
                     /locus_tag="PC366_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577615.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(472..792)
                     /locus_tag="PC366_002089"
     CDS             complement(472..792)
                     /locus_tag="PC366_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HDF2577616.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NMDK"
     gene            complement(912..1649)
                     /locus_tag="PC366_002090"
     CDS             complement(912..1649)
                     /locus_tag="PC366_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HDF2577617.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDVITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGDYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            1864..3687
                     /gene="acd"
                     /locus_tag="PC366_002091"
     CDS             1864..3687
                     /gene="acd"
                     /locus_tag="PC366_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HDF2577618.1"
                     /translation="MKKKAALATLAMLPLGVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKSNSDSLRTSTNKEKQVI
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLPKGSKVEVISESNGWSKIKYNGKDAYIS
                     SMYLSDVSQSNSDNSSQSNDKKNTDKVVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADTSNNNSNSNSDNSSNSNGNNSSSSGQVNGM
                     SGISGAKIDYKSLSYTLESHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSS
                     FVNASSSDIEYYLNPKNFTNTTKGMMQFLKINSYRDGISESSLNSYLNGLSSSVFKNQ
                     GAAFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFG
                     IGAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYVNSSKYNQNTIYKMKWNYD
                     YTWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            3902..8200
                     /locus_tag="PC366_002092"
     CDS             3902..8200
                     /locus_tag="PC366_002092"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HDF2577619.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKVNKERLIRINDREMEEKIRALEIGKVNNCEENEEESYVIKSDVDENLIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRIEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHSAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEDDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEILPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSIGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFDKIPVATGDVHFLDKHEA
                     VLRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIEEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIVVGEKTLLPPMAAIQGLG
                     GNAAINIQNERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            8404..8865
                     /locus_tag="PC366_002093"
     CDS             8404..8865
                     /locus_tag="PC366_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HDF2577620.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF"
     gene            8895..10049
                     /gene="nusA"
                     /locus_tag="PC366_002094"
     CDS             8895..10049
                     /gene="nusA"
                     /locus_tag="PC366_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HDF2577621.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVKSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELGTSEDNFSEEE"
     gene            10056..10337
                     /locus_tag="PC366_002095"
     CDS             10056..10337
                     /locus_tag="PC366_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HDF2577622.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            10327..10638
                     /locus_tag="PC366_002096"
     CDS             10327..10638
                     /locus_tag="PC366_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal L7Ae/L30e/S12e/Gadd45 family protein"
                     /protein_id="HDF2577623.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            10660..12600
                     /gene="infB"
                     /locus_tag="PC366_002097"
     CDS             10660..12600
                     /gene="infB"
                     /locus_tag="PC366_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HDF2577624.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGEELE
                     LALEMLGEDLSQENGNVIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            12643..13023
                     /gene="rbfA"
                     /locus_tag="PC366_002098"
     CDS             12643..13023
                     /gene="rbfA"
                     /locus_tag="PC366_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HDF2577625.1"
                     /translation="MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGM
                     YMDNLIKRVNEKNAQQNEDENYDE"
     gene            13004..13987
                     /locus_tag="PC366_002099"
     CDS             13004..13987
                     /locus_tag="PC366_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HDF2577626.1"
                     /translation="MKIMMNNMDSIINYIYEGDYFIVTSHISPDGDNVGSTLSMYYTL
                     KNLGKNVYYVLDDEAPLNLRFLVEGVKIYKSNEFNMKNYSLIALDCGDKMRICVSDEI
                     KNNASKLICIDHHASNDSYGDLNYVDIDASSTCELVYNLLVRFQQTKDINIINEDIAT
                     CLYTGLVTDTGNFSYSNVHASSFEMAKNLLVLGAQKNTIIQNIYQSNSSDYYKLLGEA
                     LKGLEIFDSKVSSIVLTQDMMNRNNISFNDVDGITTYTRDIKGIEVGILFKEKKQNEI
                     KVSFRSKNYVDVSEIAKLFGGGGHVRAAGCTIRDSIDNAKKMVLEAVLKSI"
     gene            14000..14905
                     /gene="truB"
                     /locus_tag="PC366_002100"
     CDS             14000..14905
                     /gene="truB"
                     /locus_tag="PC366_002100"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HDF2577627.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEDIERA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKDIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNPNAIKYYSNGGSIDDKRFLKNNFDKDDEVVRVYST
                     DNFLGLGKLSKHNNTISVKSDKMFI"
     gene            15036..15965
                     /locus_tag="PC366_002101"
     CDS             15036..15965
                     /locus_tag="PC366_002101"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HDF2577628.1"
                     /translation="MVIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEYAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMANVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            16069..16326
                     /gene="rpsO"
                     /locus_tag="PC366_002102"
     CDS             16069..16326
                     /gene="rpsO"
                     /locus_tag="PC366_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HDF2577629.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            16566..17411
                     /locus_tag="PC366_002103"
     CDS             16566..17411
                     /locus_tag="PC366_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDF2577630.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFITEGYHIICMTGAANASGTFQSAMIA
                     KNDVNENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEEIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIVTIGCGDNLHDCEILKDEVNKRIKARRVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            17536..19647
                     /gene="pnp"
                     /locus_tag="PC366_002104"
     CDS             17536..19647
                     /gene="pnp"
                     /locus_tag="PC366_002104"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HDF2577631.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCVGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            19913..20656
                     /locus_tag="PC366_002105"
     CDS             19913..20656
                     /locus_tag="PC366_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2577632.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDKSGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKPGKLSDVFK"
     gene            20814..22061
                     /locus_tag="PC366_002106"
     CDS             20814..22061
                     /locus_tag="PC366_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDF2577633.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGT
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAICLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEIENIRENYLTEKEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVNINSIKKVVDK
                     VFNIENIGTCIVGRDVEKILHLD"
     gene            22096..22341
                     /locus_tag="PC366_002107"
     CDS             22096..22341
                     /locus_tag="PC366_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HDF2577634.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGGILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            22351..23574
                     /gene="dapG"
                     /locus_tag="PC366_002108"
     CDS             22351..23574
                     /gene="dapG"
                     /locus_tag="PC366_002108"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDF2577635.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFF
                     TGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEENIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            23687..24421
                     /locus_tag="PC366_002109"
     CDS             23687..24421
                     /locus_tag="PC366_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HDF2577636.1"
                     /translation="MKDYREDNERFDKDNCSEESSCEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            24544..26955
                     /locus_tag="PC366_002110"
     CDS             24544..26955
                     /locus_tag="PC366_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDF2577637.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
                     ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGLNNDDEEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGT
                     QSMPELDVLKELQKATNENPVVDTKPEKKVDIAKSNLNIEKTQPMSIVAEPVNEDYSN
                     YKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEI
                     QPSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLE
                     SEEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYK
                     ANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFAD
                     AQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIV
                     ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAA
                     KPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKSSDEDEFLSEA
                     IEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQ
                     NLEGE"
     gene            26958..28016
                     /gene="mnmH"
                     /locus_tag="PC366_002111"
     CDS             26958..28016
                     /gene="mnmH"
                     /locus_tag="PC366_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HDF2577638.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNEVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESVFFSKENYIFVESESK
                     RVGSVTVPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNILILKECINKF
                     RKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKA
                     LEDVIDLYESILEGESEC"
     gene            28010..29344
                     /gene="rimO"
                     /locus_tag="PC366_002112"
     CDS             28010..29344
                     /gene="rimO"
                     /locus_tag="PC366_002112"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HDF2577639.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFSELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILKELSEMHQIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA"
     gene            29331..29873
                     /gene="pgsA"
                     /locus_tag="PC366_002113"
     CDS             29331..29873
                     /gene="pgsA"
                     /locus_tag="PC366_002113"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HDF2577640.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNVPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
     gene            30161..31207
                     /gene="recA"
                     /locus_tag="PC366_002114"
     CDS             30161..31207
                     /gene="recA"
                     /locus_tag="PC366_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HDF2577641.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEIDEKVRAFYNLNEEH
                     EESGTSVSKEIVEE"
     gene            31383..32924
                     /gene="rny"
                     /locus_tag="PC366_002115"
     CDS             31383..32924
                     /gene="rny"
                     /locus_tag="PC366_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HDF2577642.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
BASE COUNT        13506 a         3530 c         6360 g         9936 t
ORIGIN      
        1 aataggtaaa atatcctatt gttttgtaga tatatcctaa ttatgtcaaa aaataaaaaa
       61 atttttattt attagagttt ttggaaataa taataacaga tattataatt aattaacagt
      121 ttttgtaagt atttgacaat agagagggtg taacaaatgg gaataataga gtcagcatca
      181 aaattggctg agatggttca tttattggct gttgaaaagg ggataactga tatagaagca
      241 tgggatgaag ctgtgaaaga atacagcaaa atttatgaag aaagaagaaa tgaatagaat
      301 gataaaaaat gaaaacttga tgataaaaaa taactttatt taaagaaatt caatttttat
      361 agaaatatta aaaataatat aaataaaaag atggtatttc aaatgtaagt aaaaaatcat
      421 tttgggatac catccttatt atttatttta ataatatata agtaataaat cttacttatc
      481 catatttttt atgtaacctc ttttttctag cttttttata tgctccttac gtatttcatc
      541 aagattaata ccatattgtt cttctagctt aaacatcata gtaacacatg tctgagctac
      601 atccattagt tccttagcag ttttctttat aatatcaact tcatctaaat cattattttc
      661 tccacttaga tttctgaatt tacctataca ttcagctaat tcaccttgtt cttcacccat
      721 tttgataaat gtagattcta gtgttgggtc taaattatta agctctggta aagatatagt
      781 ttttagtttc ataaaagctc ctttcaagtt attcgtattt atactaaaac atcataacaa
      841 aaataatact aaaaaaaaac tttaaattca acataaaaac ttacatatat aataaaaatc
      901 gtgaaataaa tctatatttg tcttaataca gcctcatata aaacttctcc aataggttta
      961 tttattacaa gagaagctga cttatcatag actgtatttg ctttattaat aagagcaata
     1021 taatcacctt tgtaataatc tataaaactt gctgctgggt acacagctaa tgatgtacct
     1081 cctataatca ataaatcagc attacttata gcagaaattg ttttagtaat gacatcactg
     1141 tcaagagctt cctcataaag tactacatct ggttttacta tagaaccaca gttgtcacaa
     1201 taaggaatat tacctcccag atttaacata gattctaagt caaaaaactt accacattta
     1261 gtacaataat ttctatgtac agaaccatga agttctagca catttttact tccagccatt
     1321 tgatgaagtc catcaatatt ttgagttatg acagctttaa gcttacccat ttcctcgagt
     1381 tttgctaaag ctatatgagc attgttgggt tttgcattag gatatattaa tttatcctta
     1441 taaaattcaa aaaattcttc tggatatcta acaaaaaaag tatgtgaaac taattgttca
     1501 gcagtaaatt gtttattgag tttttggcta aataatccag tagaacttct aaagtctgga
     1561 atattagatt cagttgaaac acctgctcca ccaaaaaata caatattatt gtgattagct
     1621 attaagtctt ttaagctatt tgcatccata gttacacctc caaattatta tatataaatt
     1681 gtactacata ttaggtcttt tatgttttat taatttaaat aaatatgtag tttaataagt
     1741 taaataaagg gaatataaat aaaatgtata cagagtataa atagacaata tttactaaaa
     1801 taacaagttg tcgtataatt atattaaaat tgttttagtg tataagaagg gcgggggaag
     1861 tacgtgaaga aaaaagcagc tttagcaaca ttggctatgt tacccttagg tgtggtaaat
     1921 gcacatgctg atggagatat aggtatagtg actataaatt atttaaatgt aagaaatgag
     1981 ccaactgccg aaagtagcat agcctttgtt gctaaaaaag atgataaagt tttgattaaa
     2041 gactcttcta atggatggta taaaataaaa gctgaatctg gacaagaagg ttgggcttca
     2101 tcaaaatata tagcaaaatc aaatagtgac tctttaagaa cgtctacaaa taaagaaaaa
     2161 caagttattt caaatagttt aaatatgaga aatggagcag gtacaagtta cagagtaata
     2221 actgtactaa aaaaaggtca aaaagtagaa gtaatatcag agagtaatgg atggtctaaa
     2281 atcaaatatg atggaagact aggatatgta tctagctctt atttaggaga cgtttcaaat
     2341 tcaactaata aatcaaaaac taaacaagtg aatacaactt cactaaatgt aaggagtgga
     2401 ccaaatacaa gttatggttt gttaggcaag ttgccaaaag gaagtaaagt agaagtaata
     2461 tcagaaagta atggatggtc caaaataaag tataatggaa aagatgccta tatatctagt
     2521 atgtacttat cggatgtaag tcaaagtaat tcagacaatt ctagtcaaag caatgataaa
     2581 aagaatactg ataaggttgt aaatacagct tctttaaatg taagaagtgg accaggttct
     2641 acatatagta agttgggaaa agtttataaa ggaagtaaag taactgtact atcagaaagt
     2701 agtggatggg ctaagattaa ttttaacaat aaagaagcat ttgtagtagg caattattta
     2761 tctacttcag cagatacttc aaataataac tcaaatagta actctgataa cagttctaat
     2821 agtaatggca ataattcttc atcatcaggt caagtaaatg gtatgtcagg tataagtggg
     2881 gctaaaattg attataaatc tttgagttat actttagaat ctcatataag taaacaagtt
     2941 gagaaagcag catcaggagg aaatgtgata gctccaagta ataggaaaag cactccaagt
     3001 cctgaattta gtactttttc agctcaaaga acaagctcat ttgtaaatgc aagttcaagt
     3061 gatatagaat attatttaaa tcctaaaaat tttacaaata ctactaaagg tatgatgcag
     3121 tttttaaaga ttaacagtta tagagatggt atttcagaat caagtcttaa ctcgtatctt
     3181 aatggtttat cttctagtgt atttaaaaac cagggagcag cctttataaa tgctgccaag
     3241 aagtataata tagatgttgt atatctagta tctcatgcta tgtgggaaac tgcttatggt
     3301 aagtctacac ttgcccaagg tcaaacatta acatcttata agggacaacc tcttagtaag
     3361 ccagttaaag tatacaattt ttttggtata ggagcaatag ataaaagtgc taatgtttca
     3421 ggtgcagaag cagcgtattc caatggctgg actagtgtag aagctacaat agatggctct
     3481 gcaaagtgga tatcacaaaa ttacgtaaat agttctaagt acaatcagaa tactatctac
     3541 aagatgaagt ggaattatga ttatacatgg catcagtatg caactgatgt aaactgggct
     3601 aatggaattt ctggaattat ggaaaattta attggtcttt atggaggagg aagtagtttg
     3661 gtttttgaag ttcctcaata taagtaatac ataaataaaa aatatagact atgggtagtt
     3721 ttcattttat ttaaattatc tatagtcttt ttgtatataa tttataatct gtaaatttaa
     3781 tgttaacaaa acttttatgt tataatatta attctaagta aatataagtg agtaataggt
     3841 agaaatagat aaaaagtggt aataatatat ataaagataa ttttgagaaa ggaggatata
     3901 tatggaaagt attaaggaat atttggataa gttagaaatt aataatagtg gtcttggaaa
     3961 gcaacttaaa gaagtttata taaatagagt agtttatttt aaggaagata agatagttta
     4021 tttttatcta acttctaaag atattgtttc tcatgaactt ttagataaat ttaaagaaga
     4081 attgatgtat aaactcgatt attttaaaga tatgaggatg aagataagat ttactggtct
     4141 tgaaagaaaa tccaataaag atgttataaa aaaatattgg aataatatat tgtatatatt
     4201 aaagtatctt tgtccatcta ttgcagggtg gtataaacaa gtagaatttc tttgtttaga
     4261 agaagaatta aaaataaaac ttccaaaagg tatattttat gagcgattaa tgaaaaaaaa
     4321 tgtaacttat gtacttaaaa ccgtgcttag cgaagagttg ggattagatt taaatataac
     4381 aatagaaaaa gctgttgatg aaaaggtaaa taaagaaaga ctcataagaa tcaatgatag
     4441 agaaatggaa gaaaaaatta gggctttaga aattggaaaa gttaataact gtgaagaaaa
     4501 tgaagaggaa agctatgtca ttaagtctga tgtagatgaa aatttaatct atggagataa
     4561 tgcaaatgct atgattgaaa atatagttga attaaatgca tcttctggaa cagttgcagt
     4621 tgttggagat atatttgatg ttgacactaa agaacttaaa aacggaaaaa tacttatgat
     4681 agcttcaatt acagattata ctagctcaat aagctgtaaa ctttttttaa cagatacaaa
     4741 taaggatgga gtacttgaaa atgttaaaaa gggagcatac ttaaaaatca agggtgacat
     4801 agtttatgat acatatcaaa gagaaattag tatgatgatt agtgggataa gaaaagaaac
     4861 tagaatagag agagaagata aatcagagga aaaaagggta gaactccatg cacatacaca
     4921 aatgtcttct atggatgcta tttgttctgt taaaaagctt gtagagcgtg cagccaaatg
     4981 gggtcattct gctattgcta taacagacca tggtgttgta caaggatttc cagatgctat
     5041 gaatgcaggt aagtcaaata atataaaaat actttatgga gtagaagggt acttggttga
     5101 agatgattct ctcattatag aggatgcaaa tgataaagaa ctttcgcaga catttgttgt
     5161 atttgacata gagacaactg gtttttctaa tacaaatgat aaaataactg agattggtgc
     5221 tgtaaaaata gaaaacttta agattgtaga tagatttagt gagttaataa atcctgaaaa
     5281 agatatttcc tataagatac aggaattgac aggaataact aatgaattaa ttaaagacaa
     5341 gccaaccatt gaagaaattc ttcctaagtt tatggaattt gttggagata gtgtattagt
     5401 agcacataat gcagagtttg ataccggatt tatatcgcaa aaatgtaggg aacaaggctt
     5461 gttatataat aacaaaaaag tagatacact tatgttagca agagtaatgt tgccaaactt
     5521 aaaaagacat agattaaatg tcgttgcaaa agaacttggt attcctcttt taaatcacca
     5581 tagagcagtg gatgatgctg aggctacagc acttatattt aataagtttt tgcagatgct
     5641 tacagaaaaa ggtgcaaaaa ctctaagtga tgtaaacaat atacttggaa agattgatta
     5701 cacaaagctt agcacaaatc atataacctt gatagcaaaa aattctatag gtataaaaaa
     5761 tttatataaa ataatttcag atgcacatgt aaatcatttt tttagagcac caagaatcct
     5821 tagaagtgta ttaaatgaat ataaagaagg attaataatt ggttcggctt gtgaagctgg
     5881 ggtggttttt caagctgtaa agaaaaacgt gtctgatgag gaaatgaaaa aaataataga
     5941 tttatacgat tatattgaag taatgcctat agataataat agatttatga ttgataaagg
     6001 agaagtaaag gatgaagaag agttaaggga gttgaatagg aaattaattg atacagccaa
     6061 aaaatttgac aaaattccag tagctactgg ggatgttcat tttttagaca aacatgaagc
     6121 tgtcttaaga aaagttctta aatattctca aggttttaaa gtagatgaag aagaaactta
     6181 tttacatttt agaacaacag atgaaatgtt ggaagagttt agttatcttg gagaagaatt
     6241 ggcatatgaa gttgtagttg aaaatagtaa tctgattgcc gatatggttg aagatataaa
     6301 acctatacca gatgatactt atcctccaat tatagagggc tcagatgtgg agttaagaga
     6361 aatgtgttac aaaaaagcca aacgaatcta tggagaccca ataccagaaa tagttcaaaa
     6421 aagactggat agagaattaa attcaataat aagcaatggg tatgcagtta tgtatattat
     6481 agctcaaaaa ctggttgcaa aatctctttc agatggatat ttagttggtt caagaggctc
     6541 agttggctca tcttttgcag ctactatgag tgatataaca gaagttaatc ctcttccagc
     6601 acattatatt tgtgaaaacg aagactgtaa atattcattc ttttatgaaa taggtgaatg
     6661 gggctcaggt gttgatttac cagacaagga ttgtccaaag tgtggaagaa aacttgctaa
     6721 aaacggtcat gatattccat ttgaggtttt cttaggtttt gaaggtgata aggaaccaga
     6781 tatagactta aatttctcag gaaattatca gccaacaatt cataaataca cagaagaact
     6841 atttggagag gggtatgtat atagggctgg gactataggt actgtagcag aaaaaacagc
     6901 ttttggatac gcaagaaaat atgtggaaga aaataatata agtgtaccaa atgcagaagt
     6961 acttaggctt tcaaatggat gtactggagt aaaaagaacc tcaggacaac atcctggtgg
     7021 agttatggtt ataccagact ataaagatgt atacgatttt acacctatac agtatccagc
     7081 aaatgatact tcttgtggtg ttataactac tcactttgat tatcattcaa taagtggtag
     7141 aatacttaaa cttgatatac ttggacacga cggtcctacc attataagga tgcttgaaga
     7201 tatgactgga ataaatataa cagaaattcc tttagatgat aaagagacta tgtctctatt
     7261 tacatctaca gaagcattag gtgttacacc agaagaaata aactgtccta taggttgcct
     7321 tgctgtacca gagtttggaa ctaagtttgt acgacagatg ttacttgaca ccaaacccac
     7381 tacatttgca gaacttgtgc gtatatctgg tctctctcat gggacagatg tttgggtaaa
     7441 taatgcacaa gacttagtta gagaagatat agttggatta aaagatgtta tatctacacg
     7501 agatgacata atgaactatt taatatttaa aggattacct cccaaaatga gttttacaat
     7561 aatggagagc gtaagaaaag gtaaaggtct aaaaccagaa cacattgaag aaatgaaaaa
     7621 aaataatgtt ccagaatggt atataggctc atgtaaaaag attaagtaca tgttcccaaa
     7681 agcacatgct gttgcttatg taatgacatc atttagaatt gcatattgta aagttcacta
     7741 tccagaagca ttttatgcga cttattttac gacaaaagtt gaggattttg atgcagattt
     7801 aattgttaaa ggattagatg ctataaaatc aaaaataaat gaaattgagt cactgggaaa
     7861 tgatgcaacc acaaaagaaa aaggtatgtt gaccgtttta gaagttgctc ttgaaatgta
     7921 tgctagagga ataaaattat taccagttga tatatataaa tcagatgcaa ctgagtttat
     7981 agttgtagga gaaaaaacat tacttccacc aatggcagca atacaagggc ttggaggaaa
     8041 tgcggctata aacatccaaa atgaaagaaa aaatggtgaa tttatatcaa aagaagattt
     8101 gagaaagaga acaaaaatat caaaaacggt aatagaaact cttactaatc atggttcact
     8161 tgagaatatg agtgagagaa atcaattgtc attgttttaa gttagcccaa aaagttgcaa
     8221 ataaaagaat tttatgatat catagtatag aaaatagtat actttgcaga aactaagagt
     8281 gagacagctg ttctcactct tttattttaa atatattatt aaaaagttgg tttattttta
     8341 ttaaatatat tttatttaag attatataaa ctaatcattt acaattgaat aggaggaact
     8401 ttaatgaaaa aaaatttaga agctacaatt gaggagattg taactaaaat aacggatgaa
     8461 catggatttg aaatggttga tgttgaatat gtaaaagaag caggagaata ctacttaaga
     8521 gtatacatag ataaagaaga aggaatatct ttaaatgaat gtgaattagt tagtagagaa
     8581 ttaagtccaa tactagatga aaaagaccct ataaaagaaa attacttttt agaggtatct
     8641 tctccaggac ttgatagagc attaaaaaaa gacagagatt ttgttagata tcaaggtaga
     8701 gatgtagatt taaaattata taaaccatta aatggatgta agcaatttga aggtgaactt
     8761 gtaggattaa cagaagataa taatataaaa atcattgcaa atggtaagga aatggaattt
     8821 aatagaaaag atgttgctat tgtcagatta gcaataaagt tttagtggta tattaaatag
     8881 ggaggatata aaaaatgaat catgaattta tggaagcatt agatgaatta gtagttgaca
     8941 gaggtataga taaagaaata cttatagata ctatagaaca agctctttta actgcataca
     9001 agaaaaactt tggttcagca caaaatgtta gagttgaatt tgatagagac aagggagata
     9061 taaaagtatt ttctcaaaga gttgttgttg atgaatcaga tttatatgat actttcttag
     9121 aaatagagtt agcggatgct agagagataa accctaatta tgaattaggt gatattatag
     9181 aacatgaagt tacacctaaa aactttggaa gaattgcagc tcaaacagca aagcaagtag
     9241 ttgttcaaag aataagggaa gctgagagag aaatagtgta taatgaattt atagaaaaag
     9301 aaaatgaaat agttacagga gaggttgcta gagcaaataa aaatgttgtt tatgtaaatc
     9361 ttggaagaat agaaggtata atgactcaaa gtgaacaaat accatttgag aattataaag
     9421 caggtcaaaa aataaaattc tatatacttg aagttaaaaa gactaacaaa ggacctcaaa
     9481 tagttgtatc aagaagtcat ccgggtctag taaagagatt gtttgaagaa gaagttcctg
     9541 aaatatatga aggaatagtt caaataaaat ctgtagcaag agaagcaggg tcaagaacta
     9601 aaatggcagt aaaatctata gatgaaaaaa tagacccaat tggagcttgt gttggaccaa
     9661 aaggacttag agtaaaaaat atagtggatg aacttggcga tgagaaaata gatataataa
     9721 aatatagtga agacccagca gagtttatat cagcagcact tagcccatca aaagttgtta
     9781 gagtagatat agatgaagat gaaaagtctg ccttagtaat cgttccagat tatcagttat
     9841 cgcttgctat aggtaaagaa ggtcaaaatg caagactagc agcaaaattg actaactgga
     9901 aaatagatat taagagcgaa tctcaagcag aacaagaaat gttaaatctt gaaaattcca
     9961 aagaaataga agctgaggat gttgaagctg aatttatcga ccaagaagag ttaggtactt
    10021 cagaggataa ttttagtgaa gaagagtaag gagggatgat tttgaaaaaa gtaaaaaaag
    10081 tgcctcaaag aaaatgcata gcatgtcaag atagagactc taaaaaagag cttataagaa
    10141 tagttaaaaa taaagaagga aaaatatttt tagacccaac aggaagagcc aatggaagag
    10201 gagcatatgt atgtaaaagc tctgaatgtc taaaaaaagc tataaagagt aaagcattaa
    10261 ataaagcttt taaaatagat gttccagatg aagtctatga taatctactt atggagttag
    10321 aagaatatga aaaataataa agaaaaagta ctttcgttct tagggctcgc aactcgtgca
    10381 gggaaaatag tgtctggtga tgattcaact ttgcttgacc ttaaaaaagg aaaagtaaat
    10441 ttgattttaa tcgcagaaga tgcatcaaat aatactaaaa aactttttaa agataaatca
    10501 acttttagaa atattccata tctatttttt tcaacaaaag aggaaatagg atttgcaata
    10561 ggaaaatctc caagagcagt tgtaggaata aaagatgaaa atttttctaa aaagataatt
    10621 gaactaatag aaatttaaaa taaaataggg ggtgatcttg tgtcaaaaac aagagtatac
    10681 caaatagcag aagaattaaa tatatcaaat gaagagctta taaataagtt agctgaatta
    10741 gatataaatg taactgacaa agattcagta ttagaaggtg aagagttaga attagcactt
    10801 gaaatgttag gtgaagattt atctcaagaa aatggaaatg ttatagaaat agatggaaag
    10861 ttgacagtac aagtattagc aacgaaatta gataaatctc catcagaaat aattatgaag
    10921 cttatgaaaa tgggaactat ggcaacaata aatcaagaga taagttttga gattgctgct
    10981 ttggctgcca aagactatgg atttgaatta acagtagctg aaagtgatga tacagaagct
    11041 ttagaaatag aagctttaat ggaaattgaa gaagataaag aagaggattt aaaacctaga
    11101 ccaccagttg ttacagttat gggacatgtt gaccatggta agacatcttt actagatgca
    11161 ataagaaaaa ctgatgtgat ttcaggtgaa gctggaggaa taactcagca tataggtgct
    11221 tcagaagtta aaatcaatgg acacaaaata gtatttttag atactccagg acatgaggct
    11281 ttcacatcaa tgagagcaag aggagcacaa gttacagata tagcaatatt agtagttgca
    11341 gcagatgatg gtataatgcc tcaaacagtt gaagctataa accatgctaa agcagcaggt
    11401 gtacctttaa tagttgctat taataaaata gataaaccag gtgcaaaccc agataaggtt
    11461 aaacaggaat tagcagacca aggattatta gttgaagact ggggtggaga agtaatagca
    11521 gttccagtat cagctaagaa aaaagaagga atagatacac ttttagaaat ggtattattg
    11581 gttgctgaaa tggaagagtt aagagctaat ccaaataaaa gagcagtagg aactgttata
    11641 gaagctgagc ttgataaagg aagagggcca gttgcaacag tacttgttca aggtggtact
    11701 ttaacagtag gtgacccaat cgttgcaggt gttgcatgtg gtaaagttag agcaatgata
    11761 aatgcaaaag gtaagagagt aaaaacagca ggaccatcta cagcagttga gatattaggt
    11821 ctatcagaag ttccacaagg aggagaccaa tttgtcgaag ttccaactga taagattgct
    11881 agaagtgtag cagcaagaag acaacaaata gttagagatg aaatgttaaa atcaactcaa
    11941 agattatcac tagatgctct atttagtcaa atgagtgaag gttctataaa agaccttaat
    12001 atagttataa aagcagatgt acaaggttca gtacaggcag ttaaacaatc tttagaaaaa
    12061 ttatcaaatg aagaagttca agttaaagta atacatggtg gtgttggagc tgtaacagaa
    12121 tcagacatat tacttgcagc agcttctaac gcaataataa taggattcaa tgtaagacca
    12181 gttccaggtg cagaatctct aggagaaaaa gaaaatgttg atataagaac atatactata
    12241 atatacaagg caatagaaga tatacaagcg gctatgactg gtatgttaga ccctgaatat
    12301 gttgatgaag aaacaggaaa agctgaaata agagaaatat ataaaatatc tggtgttgga
    12361 acagtagctg gatgttatgt gactaatggt aagatattta gaaattgtaa agtaagatta
    12421 gttagagata gcataataat acatgaaggt gagcttgcag cacttaagag atttaaagat
    12481 gatgtaaaag aagttaattc tggatacgaa tgtggtatga gttttgtaaa ttataacgac
    12541 ataaaagaag gcgatatagt agaagcttat ataactaaag aagtagaaag aaaattataa
    12601 attcgtatca aagaaaatca gttagtaaag aaggtcgatg gtatggcatc atataataga
    12661 acaagaagga tagcagaaga aataagaaaa gtcgtaagta ctatgcttat aaatggagta
    12721 aaagacccta gaataacatc tatggtgagt gtaactgatg tagaagttac aaatgaccta
    12781 agatatgctt atgtatatgt aagtattcta ggtggagatg aagaatccac actaacaggt
    12841 cttaaaagtg ctggaggata tataagaaga gaagtaggaa aaaatataaa acttagatat
    12901 attcctgaga tagtatttaa acttgatgat tcaatagaaa aaggaatgta tatggataac
    12961 cttataaaaa gagttaatga aaaaaatgct caacaaaatg aggatgaaaa ttatgatgaa
    13021 taatatggat agtattataa actatattta tgagggtgac tattttatag ttacctctca
    13081 tatcagtcca gatggagaca atgttggttc tacactttca atgtattata cattgaagaa
    13141 tttaggaaaa aatgtatatt atgtacttga tgatgaagct ccattaaatt taaggttttt
    13201 ggttgaaggt gtaaaaatct ataagtctaa tgaatttaat atgaagaact attctttaat
    13261 tgcacttgat tgtggggata agatgagaat atgtgtgagt gatgaaatca aaaataatgc
    13321 atcaaaatta atctgtattg accatcatgc tagtaatgat tcatatggag atttaaatta
    13381 tgtagatatt gatgcatctt ctacatgtga actagtttat aatttattgg ttagatttca
    13441 gcaaacaaaa gatattaata ttataaatga agatatagca acatgtttat atacaggtct
    13501 tgtaactgat actggaaact tttcgtattc aaatgtacat gcaagtagtt ttgaaatggc
    13561 aaaaaattta cttgttttag gtgcacaaaa aaatactata atacaaaata tatatcaaag
    13621 caattcttct gattattata aattattagg agaagctcta aaaggtttgg agatatttga
    13681 ttcaaaggta tctagtatag ttttaactca agacatgatg aatagaaata atattagctt
    13741 taatgatgtt gatggaataa caacatatac aagagatata aaaggtatag aagttggaat
    13801 tttatttaaa gagaaaaaac aaaatgaaat taaagtgagt tttaggtcaa aaaattatgt
    13861 tgatgtaagt gaaatagcca agttatttgg cggtggtggt catgtaaggg ctgctggatg
    13921 tactattaga gatagtattg ataatgcaaa gaaaatggta ctagaggcag tgttaaaatc
    13981 aatttaaggt gacagtaaaa tgaataagat tataagtata ttgaaaccca caggtatgac
    14041 atctcatgat gttgtaagta gagtgagaaa gattttaaat ataaaaaaag ttggtcatac
    14101 aggtactctt gacccagatg cttcaggtgt tttaccaatc tgtataggga aagctacaaa
    14161 agtatgtgaa gttattttaa acaaagataa atcgtatata tgtgagctta ctttaggtat
    14221 aagtacagat acttatgatg cttcaggtga aattttaaaa aaagttgatg attttaaatt
    14281 tagtaatgaa gacatagaaa gagcttttga tacacaaaga ggagagataa atcaacttcc
    14341 tccaatttat tcagctttaa aggtaaatgg aaagagaatg tgtgatttag taagaagtgg
    14401 tagacaatct gaaattactt taaaaacaag aagagtaaat ataaaagaca taaaaatact
    14461 aagtataaaa ggtaataaag taatgtttta tgttgagtgt tctaaaggga cttatgtgag
    14521 aagtatttgc catgatatag gagaatatct gggttgtgga gctcatatgt cgtttttgaa
    14581 tagaacatct tctggtaaat ttgacttaga taattcaata acattagaag aattagaatt
    14641 attttatgaa aataaaactt tagacaaata cttatatgat atagattatg tccttgattc
    14701 gtttaattat gttgtattaa accctaatgc tataaaatat tatagtaatg gtggctcaat
    14761 agatgataaa aggtttttaa aaaataattt cgataaagat gatgaagttg taagagtata
    14821 cagtacagat aatttcttag gattaggaaa gttatcaaaa cacaataata caataagtgt
    14881 taaaagtgat aagatgttca tataaccaat gtatttaaaa aaacaacaaa agagatagta
    14941 ctataataac ttctatagtc tatctctttt acttatgcta taatagtttg tgaataagtt
    15001 aagagtaaat tatattttag cggggaacat ttattatggt gattataaaa tctataaaag
    15061 aaatagcaaa cataaaagaa agtgtcatta ccataggaaa ttttgatggt gtacacaaag
    15121 gacatcaagt tcttatagga aaaacagttg aatatgcaaa aaaagaaaat atacagagta
    15181 ttgtatttac atttgcaaat catcctgtaa attactttag accaaactca acaaaaaata
    15241 ttataagcaa tgatgataaa ataaaattat tagaagattt gggaatagat atagttgtaa
    15301 tcataccatt tgatgagtat atgactaaaa tacctgcaaa ggatttcgta gatgagatac
    15361 tagtaaaaaa attaaaagct aaaaagatag taattggaca tgactttaca tttgcaaggg
    15421 caaaagaagg caatgttaat ctattaaaaa gcttagaaca tgaatttggt tttgaggtag
    15481 aagtaataaa acccatcaaa atcaatgatg taagagtgag tagtacttat attagaagtt
    15541 tagtatccca gggtgatatg gctaatgtca aggaatattt gggtagaaat tacaagttag
    15601 aaggttgtgt tatacattct aaacaccttg gaagaactat aggattccca acggcaaata
    15661 ttgaccttaa gaataatatg ctcgttccaa agagaggtat ttatgcttct attgtacata
    15721 ttggagatga gacttatttt ggtgctacaa atgtaggcta taacccaaca gttaatggaa
    15781 aaactttgtc tattgaaaca aatattttag agtttgatag agatatttat ggggaaaata
    15841 taattgttga atttttggaa agaataagag atgaaagaaa gtttaattca atagatgact
    15901 taaaaaatca attgtataat gatacaaatt atgtgtatga aaactatgtt tgcaaaaaca
    15961 agtaatgtat gataaaatga ttaaggaaaa taaccattac tcggcatttg aatactccaa
    16021 tcaatgctta gtaataggcg tttctaaaaa aatacggagg taatctaaat gataaacaaa
    16081 tcagaaataa taaaagaata tggaagagct gaaggggata ctggttctcc agaagtacaa
    16141 atagctttat taacagctag aataaacgag ttaaatggac atttaaaaac tcataagaaa
    16201 gaccaccatt caagaagagg actattaaaa atggttggta gaagaagaaa cttattagct
    16261 tacttaaagg aaaaagatct tgaaggatat agagcattaa tagctaaatt aggattaaga
    16321 aagtaatttc attctttata aaaaagcagg tatagtgtat acctgctttt ttatagttaa
    16381 ttcattataa agtaaaatag ttaataataa aagtagttta tatgttataa aaaattataa
    16441 aatgaataat attgggtaag aatattaaaa tagtatacaa atacataatc aatttaaaag
    16501 gaaagacagg ataaatatag aaattttata acaggataat tagttggaat aaggaggata
    16561 ttattttgaa aataaagtta gtatgcgata gtttgtgcga tattccagat gaaatatcag
    16621 aaaaagatta tatagagata gttccactta cagttatttt taatgatagg gaatatatag
    16681 aaggagtaga tataaagaaa gaagagtttt ataaaaaagt aaaagaaatc aagcaaatac
    16741 ctaaaacttc acaagctaca tatatggagt ttaaagaagt gtttgataag ttcataacag
    16801 aaggttatca tataatctgt atgacagggg ctgcaaacgc atcaggaact tttcaaagtg
    16861 ctatgatagc taaaaatgat gtaaatgaaa atgaaaaaat acatatattt gatactagaa
    16921 atttatctct aggtagtgga caatatgtta taaaggcatg tgaacttctt gaagaaggac
    16981 tgggatttga agaaattata gatgaattag aaaatactcg cagtagtgta agattacttt
    17041 ttgcaccata tacacttgat tttttaaagc agagtggaag agttccagtt gcaactgctt
    17101 tgataggaaa tatgttaaat ataaagccta tatttttctt tgataatggg gaagctaagt
    17161 tggtaaataa ggttagagga ataaagaata tagcaagtaa actggtcgat ataattttag
    17221 aaatgaatga agggtcttta gaaggaaaaa tcgtcacaat aggttgtgga gataatttac
    17281 acgattgtga aatattaaaa gatgaagtaa ataaaagaat aaaagcaaga agagtattat
    17341 ttactcgagg aggagtttct atttgctctc atacagggcc agatatattg gctataagtt
    17401 gttctaatta gtagtaatat aaggtttttg catatatatg tgaagataat tttatattgt
    17461 taatttatag tatttttgat aatatagtaa atagagtgat atacgtgttt tttaataaga
    17521 ggaggacaag cattaatgtt tgaacataaa atatttaaaa tggattttgc aggaagagaa
    17581 ctttctgtag aaataggaaa gatttgtgaa atggctagtg gtagttgtat agttcgatac
    17641 agtgacagta tggtaatggt aaatacaact aaatcagcca aacctagaga cggaatagac
    17701 ttttttcctt taagtgtgga ttatgaagaa aaattatact ctgtaggtaa gatacctgga
    17761 ggttttttaa agagagaagg gaagccttca gaaaaagcta tacttacatc aagattgata
    17821 gatagaccaa taagaccttt attcccaaaa ggatttagaa atgatgttca ggtagttgca
    17881 acagttctat cagtagacca agattgtaca ccagatatag tagcaatgat aggttcttca
    17941 atagcccttt ctatatcaga cataccattt aatggaccaa caggttcagt atgtgttggc
    18001 cttgtagatg gtgcatttgt tgtaaatcca aacgcagagc aaagagaaaa aagttcaatg
    18061 catctagttg tttcaggtac aaaggaagca ataatgatgg ttgaagccgg agctgatgaa
    18121 gttccagatg aggtaatgct tgatgctatt ttatttgctc accaagaaat aaaaaaaata
    18181 gttgagttta tagaaggtat agttgcagaa gttggaaaag aaaaaatgcc tgttgaatta
    18241 taccatgcag gagaagaaat aactcaattg gttcgcgaat ttgcaactga taagatgaaa
    18301 aaagcagttc agacttttga aaagttagag agaatggaaa atatggatag agttaaagaa
    18361 gaaactttag ctcactttga agaaacttta gaagattttg aagattttgt tggagatata
    18421 gaagaagtat tacaagatat aataaaagaa gaagtaagaa aacttatagt acatgaaaat
    18481 gtaagaccag ataatagaaa acttgaagaa ataagaccta tatggtgtga aactggcatg
    18541 atacctagag ctcatggttc agccatattt actagaggac aaactcaagt acttaatgtt
    18601 gctactttag gtgctttagg agatgttcaa aaattagatg ggttagatga agaagaaaac
    18661 aagagatata tgcatcatta taatttcccc gcatatagtg ttggagaagc tagaccatca
    18721 agaggaccag gaagaagaga aataggacat ggtgctttag cagaaagagc tttattacca
    18781 gtaataccat ctcaagaaga atttccttat gctattagat tagtttctga agtattaagt
    18841 tcaaatggtt ctacatctca agcaagtgta tgtggctcaa cattatcttt acttgatgca
    18901 ggtgtaccta taaaagatat ggttgcaggt atagcaatgg gacttataaa gcatgatggt
    18961 aaggttgcag tgctttcaga tatacaaggt atggaagacc atttaggcga tatggacttt
    19021 aaagtagctg gaacagagta tggtataaca gcaatacaaa tggatataaa aattgatggt
    19081 atagataaag aaattctaca acgtgcttta aaacaagcta aagagggtag aatccatata
    19141 ctaggagaga tgagaaaaac tatatctcag ccaaaaccag aactttcacc atatgcacct
    19201 aagattgtta aaatgcaaat aaatcctgac aagataaaag atgtaatagg gcctggtgga
    19261 aagataataa ctaagataat agacgaaact ggagttaaga tagatattga acaaactggg
    19321 gaagtattta tatcaggtat tgagattgat atgattaaga aagctcaaga acttataaat
    19381 aatatagtag ttgaaccaga agtaggaaaa acttataaag gtaaggtaag tagaataatg
    19441 aactttggag catttgttga aatacttcca ggaaaagaag gattacttca tatatctcat
    19501 atagctcatg aaagagttgc caaagttgaa gatgtattga atatagggga tgaagttgaa
    19561 gttaaagtta cagagattga tgaaaaagga agagttaatt tatcaagaaa agttctttta
    19621 ccaaaaccag aacataaaaa taaataactt attatataat taaaagcaaa gtcttaggat
    19681 tttgcttttt taaatacaaa aaagtagata attttaaaat gatagttatg gatggcttat
    19741 agttcttttt ctgtaaggct ttactcttat aaagaagcta tttaaaagct gattaataga
    19801 aagctttatt gatatatata gaatcactta agttatattt agtgcataaa cagagcttat
    19861 ttttaatagt attaaataag aaacaatttg tacataatta gggggagttt taatgataat
    19921 gatggtactt aataagagta agctcaaaaa aatcataata ctaattttag tagtgttatt
    19981 agtattatca ggaggggtaa tggtattaaa gttatttaac aacaagccag tatttaattt
    20041 atttaatggt gtagatttac catatgaaag aggtacaaag gataaaagtg gatatgttgc
    20101 attaacctgt aatatagacc ttggatggga aacagagtac gtagaatcca ttttagaaac
    20161 acttaaaaaa gaaaatgtaa agattacatt taatgtaact ggaaaatggg cagaaaagaa
    20221 taaggatgaa ttattaaaga taaaaaaaca aggacatgaa ataggtaatc atggatataa
    20281 acatttagat tattctacat tatcatatga agacaattat gagcaaatag agacctctaa
    20341 aaagataatt gaagaaatta taggtgaaaa aactaaattt tttcaagcac cagcaggttc
    20401 ctttggtcca gaaacagtaa aggctgctaa agcattaggg tatacttcta tcaaatggga
    20461 tgccgatact atagattgga aatacaaaga ccaaccagag gtaatcattg atagaatgaa
    20521 gaaaaaagac attaaagata gtagtataat cttaatgcat ccaaccaacg caacgacaaa
    20581 atgtatagat gatattatag ctattgtaag agaaaaagga ctaaaaccag ggaaacttag
    20641 tgatgtattt aagtagacaa agtataaata tttggttaag attgtataag ttgtagttga
    20701 attaattaaa agactgactt ataatgtaat acatataaaa aataaatata attaaaacat
    20761 agtgttttca ataatccaat atgaaacaaa gaataaattg ttaggagaat gtaatgtata
    20821 agacaaaaat actggaaaat gggcttacaa taattggtga agaaatacca tatctaaagt
    20881 caataacatt aggtatttgg ataaatgcag gctctaggat agaagaagca caggtgagtg
    20941 gaacttctca ttttatagag catatgatgt ttaaaggaac caaaaacaga acatcaaaag
    21001 agattgctag ttcaatagat aatttgggtg gtcaaataaa tgcatttaca agtaaagaat
    21061 gtacatgtta ttatgtaaaa ctaatagatg agcatataga tacgggaatt gatgtattga
    21121 gtgatatgat actaaattct aaatttgata aaaatgatat agataaggaa agacttataa
    21181 tattggaaga acttaagatg tatgaagact ctccagatga cttatcttat gatttattag
    21241 tggaaaatat atatgctaat gatggattag gaatgaatat aattgggaca aaagaatctc
    21301 tatacaatat aactagagaa tccatgttag aatacttaaa taagtattat attccaaata
    21361 acgctgttat ttctatagct ggaaacttta actttgatga tatggtggag aaaatcaaat
    21421 caaaatttgg acactgggaa aagaaaaatt tgagtataga cataagtgag gctaagttta
    21481 atccttgctt tatatcaaaa aataaagata ctgaacaggt gaacttagct atctgcctaa
    21541 aaggtattcc ttttgaaaat gatgaagaag tctactcaat ggcagtggta aataatattt
    21601 tcggtggaag tataagctca aggctttttc agaaaataag ggaagaaaaa ggtttagtat
    21661 attcaatata ctcatcacag acattatata ggaaatgtgg tgaattaggc atatttgcaa
    21721 gtatgagtac agaaaattta caagatgtat ataatttaat aaagaaagaa attgaaaata
    21781 taagagaaaa ctatcttaca gaaaaagaaa tatctgaaag caaggaacag ttaaaaggaa
    21841 attatatatt ggatttagaa agtactagca gtagaatgat gtctactggt aaatctatgt
    21901 tacttagcaa aaaagtaaaa actacagatg aaatacttga atgtataaat aatgttaata
    21961 ttaattcaat aaagaaggtt gttgataagg tattcaatat cgaaaatatt ggtacatgta
    22021 tagttggaag agatgtagaa aagattctac acttggatta atattgaaaa aagtaaatct
    22081 ctggaggtat aaaatatgaa tttatctgaa atagcaggta aggaaatagt taacttggtc
    22141 acaggagaaa gattgggggt cattggagaa tgtgacctta tactagatga aactacaggc
    22201 ggtatattag cgcttctaat tccaaaggaa aaaggatttt ttgccagaag aaaagataag
    22261 tcatttttag aagtaccatg gagaaatgta aaaaaaatag gtaatgacat gataattata
    22321 gaatatgagg gatatattta ggaggaaaaa atgagtattt tagtgcaaaa gtttggtggg
    22381 acatcagtag aatcatatga aaaaatgaat gaagtatgta agatagtaaa agcatacaaa
    22441 aaaaatgatg aagaattaca attagtatta gtagtttcag caatgggaag aaaaggagct
    22501 ccatatgcta cagatacact tataaatttg tgtagtgcag taaatgatga gccaagtaaa
    22561 agagaacttg atttaataat gtcttgtgga gaaataatat caggaacaat tcttgctaat
    22621 ttattgaatg cacaggggat agattctgtt ttctttactg gtcagcaagc aggtataatt
    22681 acaagtgatg aatattctaa tgcaaagata aagtatataa atcctaaaaa ggtaaaaaga
    22741 gctttagatg atggtaaggt tgtagttata gctggattcc agggtgtaac agatgatgga
    22801 gaaataacta ctcttggaag aggaggaagc gatacatcag cagttgctat tggtaaagct
    22861 ttagaatgtg aaacagttga aatttacact gatgtggatg gtataatgac tgcagaccct
    22921 agagtagaac caaacgctaa agtattgagt tttatagatt atgaggaagt attccaaatg
    22981 gctgacaaag gtgcaaaagt aatacatcca agagcagtac agttggctaa aagtggaaat
    23041 ataactttag ccataaagaa tacaatgaat ccaacttttg aaggtacaaa aataggttct
    23101 ttatgtagac acttagaaga gaatatagaa tatgaacaag aaagagattt taaggttgct
    23161 gttgcaaata aagatagtgt agcacaagtt aagattaaat cagcagaaga agtgtttaca
    23221 gaagtattaa atgagataga aaagaaactt ataactatag atatgataaa tttctttata
    23281 tcagaaaaag catttgttgt agaagatgct gatataaaat cattaaagga aatactagat
    23341 aaatttgaat tagattatga agtaaataga gactgtgcta aggtaacatt gatatgttca
    23401 agaattgctg atgaaatgtc tggtatcatg tcaaaggtag ttagaggatt atcaaaagca
    23461 ggggtatctc ttttacaaac atcagactca aatatgacta tatcttgttt agttagtgaa
    23521 gaagatatgc atacagcagt acatgctata caccaacaat tttatttaaa ataaactgta
    23581 taatacaatt attttttaat caaatttaag aatttcatat atatcttaat atatttgatt
    23641 tatttggtaa aactaaatta aatataattt tgataggagt ttttttatga aagattatag
    23701 agaagataat gaaagatttg ataaagataa ttgtagtgaa gaatctagtt gcgaagagag
    23761 agaatgtata aagcaatttg gtaccaatga aatgccacct caacctccta aagatattca
    23821 atgtataact ataattggag aaattgaggg acattttata ggaaatcctc aaaaaaaagc
    23881 tacaaagtac gagcatataa ttccaatgct atactcaatt gaggaaagca atgatgttaa
    23941 aggagtgtta gttgttttaa acactgttgg aggagatatt gaagcaggtt tagctattgc
    24001 agaactttta aacagtacat ctaaaaaagt agttactctt gttctaggag gaagtcatag
    24061 tataggtgtt cctcttgcta cagcaggaga ttactcattt atagcaccaa cagcaaccat
    24121 gattatacat ccagtgcgaa ctactggtct tgtgattggt ataaatgaga cttttgaata
    24181 ttttaaaaag atgcaagata gaataattca atttataata agaacatcaa atatcaaaaa
    24241 agatgtactt gaaaaactta tgcatgaaaa agatgaactt gtaagtgatg ttggtagtgt
    24301 attaatagga aaagaagctg tggattatgg tcttatagat gaagttggag gactaaaaga
    24361 agcacttaaa aaattaagag agcttataaa agaatctgag gaagaaaaaa ataatgatta
    24421 aaatttgttt aaataataaa atttatgata taatgatgta ataaagtagg agtgttagtg
    24481 ttaaggcatt agcacttttt gctgtgaagg ggtaaaactt gctaaaaata aggagtgata
    24541 ttaatggcca cgaaaaagaa gaaaaaaaag aaggtaaata ccttaagttt taatgcagaa
    24601 tatcataatt taataacaat atttataggt gtatttttat tatatagttt aaattctaat
    24661 tctatgggat ggatacctgt gttaatgcaa aatcttttta agggactatt tggagggctt
    24721 tcaatagcaa taccatttat agtaattata acaggacttt taggattttt tgatggaaat
    24781 gaatatatat ataggctaag aaagactaaa ctatactaca taattatttt atttatattt
    24841 gtattttatg gattattaaa tgcaggaact cttcctgtag atagcccact aaaaggtaac
    24901 atgtttgatg atgttatgaa attgggtgta agtggacaag gtagtggttt gatagcaaca
    24961 actattgcgt attatatgag taaaatattt ggtatagcag gtggatggtt aataagtatc
    25021 ttcgcactta tactttctgt aatgtttata tttaatattt ctataaaaga tttggtgtca
    25081 aatgcaaaat caaaatctaa agcatctaaa gacagcaatt taacgtttaa agataaaatt
    25141 gcaaatatga aaaaatctgc aatagatatg atgactgatg aagtagatga tactactata
    25201 aataaaaaac caggtttctt taaagggtta atgtcaaaag gtcttaataa tgatgatgaa
    25261 gaagatgaat attttgaaga agaaaatagt gatggtgtag atgataaaac tataaaaata
    25321 gttggattta ataaggcaga agatgagtat ttagaaatat tagaaggaac tcaaagtatg
    25381 ccagagttag atgttttaaa agaattacaa aaagctacca atgaaaatcc agttgtagat
    25441 actaaaccag aaaaaaaagt tgatatagct aaatctaatt taaatataga aaaaactcaa
    25501 cctatgagta ttgtagcaga gccagttaat gaggattatt caaactataa aaagcctagc
    25561 attgagcttt taaataaagt aaataagaag tctgatgaaa atggtaaaaa gaaagtgttg
    25621 aaaaatgctt ctcttttaga aaagacacta tcagattttg gagtggaagc aaaaattaat
    25681 caagttacag ttggacctac tataacaaga tatgaaatac aaccaagtcc aggagtcaag
    25741 gtaagtaaaa ttgtaaattt aactgatgat atagctttaa gtttagcagc taaaagtata
    25801 agaattgaag ccccaattcc tggtaaaagt gcaattggaa tagaagttcc aaatgaagaa
    25861 gctcaaatgg ttggtgtgag agaagttcta gaaagtgaag aatttaataa ttttaactct
    25921 cctcttgcaa tgggacttgg aaaagacgta gcaggaaaaa ttataattgg agatataggt
    25981 aagatgccac acttactaat agctggttct acaggttcag gaaagagtgt gtgtgtaaat
    26041 acattaataa gtagtatttt atataaggca aatcctgatg aagtaaaatt actattaata
    26101 gacccaaaag tagttgaact tgcaaattat aatggaatac cacatctatt gataccagta
    26161 gttactgacc ctaaaaaagc tgcaaatgct ttaaattggg cagttacaga gatgaataga
    26221 aggtataaat tatttgcaga tgctcaagta aaagatgtaa caagttataa tgagaaagcg
    26281 gaagaaaaac ttcctaaaat agtaataata atagatgagt tagcagattt aatgatggca
    26341 agtgcaaatg atgtagaaga ttatatttgt agattagctc aaatggcaag agctgctgga
    26401 atgcacttga ttgtagcaac tcaaagacca tctgttgacg ttataacagg ggtaataaag
    26461 gctaatatac catctagaat agcatttgca gtatcatctc aaactgattc aagaacaatc
    26521 cttgatatgg gtggtgcaga gaagcttcta ggtaaaggtg atatgttatt ctatccactt
    26581 ggtgcagcaa aaccagttag acttcaaggg gcattcatat cagagagtga gtcggaaaaa
    26641 gtaattgatt ttgtaaaaag tcaggttaaa gatggaataa aatatgaaga agatataatt
    26701 gaaactatat ctaaggttaa tacttcaaag agtagtgatg aggatgagtt tttgagtgaa
    26761 gcgatagaat ttgtcgtgga aagtggtcaa gcatctgcct ctatgctaca gagaagattt
    26821 aaaataggat tcaatagagc agctagactt atagattcta tggaagaaag aggcataatt
    26881 ggagcaagtg agggaagtaa acctagaaag gtattaataa gcaaacagga tttgcagaat
    26941 ttagaaggtg aatagaattg tcagttataa aaatagaaaa agcacttaag ctagataaag
    27001 taatatttgt agatgtgaga actgaaggag aatatgaaga agaccatata ttgaatgcaa
    27061 tcaatatgcc tctttttaaa aataatgaac ataatgaagt tggaacaatt tataagatgc
    27121 agggaaaaca tgaagcaata caaaaagggt ttgactatgt atcgtataaa ttaaaggata
    27181 tatatttaca agcagcagaa cttgcattaa attatgataa tattgtcata tattgtgcaa
    27241 gaggcggaat gagaagtgga agtatagtaa atttattatc atcattaggt gtaaatgtat
    27301 atcaacttga aggtggatat aaggcttata gaaattttgt attagagtat ctaaggcatg
    27361 taatggatac aaaaaacttt gtatctgttc atggattgac tggtacagga aagactgatt
    27421 tgttacattt attagatgaa aaaggaatag atgtactgga tttagaaggc atagctaaaa
    27481 acagtggttc tacctttggt tttataactt ttgataaaaa gccaccatct caaaagaact
    27541 ttgaaacaaa actatttgaa agtgtatttt tttcgaaaga gaattatata tttgtcgaga
    27601 gtgaaagcaa acgagttgga agtgttacag ttccaaatga aattttcgag gcaatgacac
    27661 gagaaggaca tcatatatta ttagaatgtg atattgaaaa tagagttgat agactttgta
    27721 gagattatat ttatgataaa gatgaaggta atatattgat tttaaaagaa tgtataaaca
    27781 agtttagaaa aagattgggt aataaagtag tagatgatta tattgattta ttagaatcag
    27841 gtgaatataa agaacttgta aaaagatatc ttttagaata ctacgaccca ctttatatgc
    27901 attcagtaga gaaatataag tatagtaaga ttataaattt taatgataca caaaaagctt
    27961 tagaagatgt tatagactta tatgagagta tattggaagg agaaagtgaa tgttaaaaat
    28021 agcattggaa tcattaggat gctcaaaaaa tttagtagat gcagaaataa tgatgggaat
    28081 tttaaataac aaaggctata aattaattgg agattttgaa gaagctgatg taattatagt
    28141 aaatacatgt gggtttatag agtcagctaa acaagaatct atagatacga taataaactt
    28201 ttcagagtta aaaaaaactg gcaatttaaa gttgttgata gtaacagggt gtctagccca
    28261 aagatattct gaagaattaa aaactgaaat tcctgaaata gatgctatag taggaacagg
    28321 aagctatcaa aatatagata aaatacttaa agaattaagt gaaatgcatc aaattgtaag
    28381 ccttaatgat atagagtttg tatttaatga agatttacca agatatatat ctacacctag
    28441 ctatatggcc tatttaaaaa ttggagaagg atgctccaat aattgtactt attgtataat
    28501 accaaaacta agaggtaaat atagaagtag aaaatttgaa gatataatta aagaagctaa
    28561 gaaattagct gaatctggag taaaagaact tgtggttata gcacaagata cgacaaagta
    28621 tggttttgat ttatatggaa aagaaagatt atcagaactt ttagaagaac ttgcaaaaat
    28681 agatggattt aagtggataa gggttatgta ttcatatcca gaatctataa cagaggaatt
    28741 gatacaagtt ataaagaaat atgataatat atgtagttac tttgatatgc caatacagca
    28801 tgcaagtaac aatattttaa aattaatgaa tagaaaaact actaaagaag atatattaaa
    28861 taaaatcaat ctgataagaa gtaatatacc agatgctata cttagaacta cgataatagt
    28921 agggtttcct ggtgaaacag aagatgactt caaacaactt gtggactttg ttgaagaggt
    28981 taaatttgat agacttggtg catttgcata ttcaagagaa gaagatacac cagcagatag
    29041 attgccaaac catatagatg aagaagtaaa aatacaaaga agagatactt taatgatgat
    29101 tcaacaaaaa atatctgaag aacttaatga caaaaagata ggaaaaactt atgaggtgtt
    29161 aatagaagaa cagatagaag ataatgtata tacaggaaga acacaaggtg atgcggaaga
    29221 aattgacagt atagtgtatg taaaaagtgt agacaatctt gaagtaggag aatttgtaag
    29281 tgttcaaata aatgatgcaa tggaatacga tttaatggga gatgttttat atgaacttgc
    29341 ctaacaagtt aactttgttt agaatatttt taataccagt atttgtttta attatgttgc
    29401 tcaatgtacc aaataaattt ttaatagctt gtattatttt tataatagct tcaattactg
    29461 atgctttaga tggaaaaata gctagaaaat acaatctagt cactgacttt ggaaaattta
    29521 tggacccatt agcagataag ttattggtta tttcagcact tacatgtatg atagaagacc
    29581 atcttgtaag tagttggatg gtaattataa tagtggctag agagcttaca gttagcatat
    29641 taagagctat agctgctgct gatggaaaag taattgctgc tggaaacagt ggaaaactta
    29701 aaacgataac tcaaatggta tctatagtgt ttttattgtt aggcgctcag tttgaaaatg
    29761 tattgatatt aaatattggt gaaattctca ttcttatagc tacactactt acattatatt
    29821 ctggatggga atatctatat aaaaataaag agctttttat gtcttctaag taaaaaatta
    29881 tgctttaata aataaaaact aatgattaat aaataaaaaa taacaactta aaattttaaa
    29941 aatgtaaaaa agggtatact attatagtat acctcttttc attttaagaa tattttcttt
    30001 tgtgtatata attattaata atggtttata aataaaatgt aatgaataaa aatataatca
    30061 ttagtagcgt ttttaaattg actaggtttg atttatgtta tataattaat atataacaag
    30121 agaacaaatg tttgtagata aatgaaggga tggtatagag atgagtgtag atcaagaaaa
    30181 attaaaagcg ttgaatgaag ctttaggtaa aattgaaaaa gattttggta aaggttcagt
    30241 aatgaaattg ggagaagcaa catctatgtc tatagatgtt atatcaacag gagcgattgg
    30301 tttagacata gctattggta taggaggtct acctagaggg agaatagttg aagtatatgg
    30361 tccagaatct tctggtaaga ctactgttgc gcttagttgt gtagcatcag ctcaaaaaga
    30421 tggaggaata gctgcattta tagatgcaga acatgcactt gacccagtat atgcaaaagc
    30481 tttgggtgtg gatgttgata acctaataat atctcaacca gatacaggtg aacaggcttt
    30541 agagatagca gaggcattga taagaagtgg agcgatagat ataatagtaa tagactcagt
    30601 agcagcatta gttccaaagg ctgaaataga tggagatatg ggtgattctc atgtaggttt
    30661 acaagctaga cttatgtcac aagcacttag aaagttaact ggttcaatta aaaaatcaaa
    30721 ttgtgttgct atatttataa accagttaag agagaaagta ggaataatgt ttggaaaccc
    30781 agaaactact actggaggac gtgcactaaa attctattca tcagttagat tggatgttag
    30841 aaaaatagat acaataaaac aaggtgataa agttataggt agtagaacta gagttaaagt
    30901 tgttaaaaac aaagtagcac caccatttaa gcaagctgaa tttgatataa tgtatggaga
    30961 agggatttca aaaattggag accttttaga tatagctgct gatgtagata tagttaaaaa
    31021 atcaggttca tggtatagtt acaatgatac taaacttgga caaggaagag aaaatgttaa
    31081 aaaattcttg gaagataatt tagatttaac tactgaaata gatgagaaag ttagagcatt
    31141 ttacaattta aatgaagaac atgaagaatc aggtacttca gtatcaaaag aaattgtaga
    31201 agaataagta aaaatacaaa aaaataacta gtaattaaag acatgccacg ctccctatta
    31261 gcttgacaca atgttgaaaa aattataaaa ttaagtgagg ataaaatatc taaatttaat
    31321 tttaattatt aggaatattt tttaatcata gtgatgacat tttgggatta ttaacgaagg
    31381 aggtggatgt catagatagt gtagtaatga ttgtaatagg tgcagctgtt ggtattatag
    31441 ctggatattt tgttagaaaa aatatatctg aagcaaaaat tggacaagct gaaaacttgg
    31501 ccaaagaaat aatagataaa gcacaccacg actcagaaac agtacaaaaa gaaaaattac
    31561 tagaagctaa agaagagatc cataagtgga gaacagaagc tgaaagagaa aacagagaaa
    31621 gaagaacaga agtacaaaag tatgaaaaaa gagtagtaca aaaagaagaa gtcttagata
    31681 gaaaattaca aaatttagaa tctaaagaag taaacctaag tgaaaaatta aaggtagtgg
    31741 aaaagaaaga agaagaagtc gaagtaataa aaactcaaca gttagaaaaa ttagaaagta
    31801 tatcaggaat tacttctgat aaggccaaag aaatcatctt aaccaatgcg gagagagatg
    31861 taagacgtga aatgtctata atgataaaag agatagaaag tcaagctaaa gaagaagctg
    31921 ataagaaatc aagagaaatt ataggatatg caattcaaaa atgtgcagca gatcacgtag
    31981 ccgaaactac tgtaacagta gtaagcttgc ctaatgatga aatgaaaggt agaataatag
    32041 gtagggaagg tagaaatata aggactttag aaaccttaac aggtatagac cttataatag
    32101 atgacactcc agaagccgta attttatcag gatttgatcc aataagaaga gaaattgcaa
    32161 gaattgctct agaaaaatta atagcagatg gaagaataca tccagctaga attgaagaaa
    32221 tggttgaaaa ggcgagaaaa gaagttgaca atattataaa agaatatggt gaacaagctg
    32281 catttgaaac tagtgtacat gggattcatc cggaattaat aagattatta ggtagactta
    32341 actatagaac tagttatgga caaaatgtac ttaaacattc tatagaagtt gctcatatag
    32401 ctggtataat ggctgctgaa ataggagcag atattagatt ggctaagagg gcaggtttat
    32461 tacatgatat aggtaaggct gtagaccatg aaatggaagg tacacatgtt gaaataggta
    32521 tggatttact tagacgttat aaagagtcta aagaagttat acatgccatg agtactcatc
    32581 atggagatta cgaacctcaa acagtagagg ctgtattagt tacagcagca gatgcaatat
    32641 cagctgctag acctggtgcg agaagagaaa ctttagaagc atatataaag agacttgaaa
    32701 aattagaaga aatagctaat tcatatgaag gtgtagaaaa atcatttgct atacaagctg
    32761 gtagagaaat aagaataatg gtaaaaccag aagctataaa tgatgaagaa atacatctat
    32821 tggctagaga tatgactaag aaaatagagg atgaacttga atatcctgga caaataaaag
    32881 taagcataat aagagaaaca agagctatag agtatgcgaa gtaaaagaaa taatatctaa
    32941 ataataagaa aatattttta gaaatttaaa tttgccacaa gatatgataa tatatcttgt
    33001 ggcttttaaa ttgtttaagt ttaattttat ataatgcaaa aataatctaa gtgctaaaag
    33061 tgctacttac aaaagattaa taaaataaag ctttatatat gtattattta tataattatc
    33121 caagtttgtt tgatataatg aagttgtaaa atcaatactt tactacaaaa taaatagtaa
    33181 atactacagt aaaatctaaa aataggatat aatagtatta atataagaag attataaata
    33241 aaacctgcta atgaaaatag attattttta gcaggttttt aaatttttta taataaatct
    33301 tatttttagt caacaagatt tatttttttt aa
//
LOCUS       DAMJWO010000044        33180 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.045, whole genome shotgun sequence.
ACCESSION   DAMJWO010000044 DAMJWO010000000
VERSION     DAMJWO010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33180
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.045"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(69..2735)
                     /locus_tag="PC366_002116"
     CDS             complement(69..2735)
                     /locus_tag="PC366_002116"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HDF2577643.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKAHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKVKKEKFEEMIKSVEERLTNLESKIK"
     misc_binding    complement(2811..3073)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(3374..4201)
                     /locus_tag="PC366_002117"
     CDS             complement(3374..4201)
                     /locus_tag="PC366_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2577644.1"
                     /translation="MKIKDNKAVFHVFIRIFLIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     gene            complement(4249..5685)
                     /locus_tag="PC366_002118"
     CDS             complement(4249..5685)
                     /locus_tag="PC366_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HDF2577645.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            complement(5772..6641)
                     /locus_tag="PC366_002119"
     CDS             complement(5772..6641)
                     /locus_tag="PC366_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDF2577646.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGNYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            complement(6799..7452)
                     /gene="phoU"
                     /locus_tag="PC366_002120"
     CDS             complement(6799..7452)
                     /gene="phoU"
                     /locus_tag="PC366_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HDF2577647.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            complement(7480..8244)
                     /gene="pstB"
                     /locus_tag="PC366_002121"
     CDS             complement(7480..8244)
                     /gene="pstB"
                     /locus_tag="PC366_002121"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDF2577648.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            complement(8263..9087)
                     /gene="pstA"
                     /locus_tag="PC366_002122"
     CDS             complement(8263..9087)
                     /gene="pstA"
                     /locus_tag="PC366_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HDF2577649.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVIIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            complement(9089..10006)
                     /gene="pstC"
                     /locus_tag="PC366_002123"
     CDS             complement(9089..10006)
                     /gene="pstC"
                     /locus_tag="PC366_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HDF2577650.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            complement(10388..11623)
                     /locus_tag="PC366_002124"
     CDS             complement(10388..11623)
                     /locus_tag="PC366_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577651.1"
                     /translation="MRIFYLEIKRVLHSRRTLILLLLALVLSALMAFLPITYEGINYL
                     DNNGKVVELSGLDAIKYKKTIYANNSEISSGVVTPKKLKHALNIWKKTEEKYGKVGSE
                     DFPLDIYSKSILPIRPLLNRLPEAFANSETGFATELSEINTNDLDSFYEQCKTHLNDI
                     MKIERQTSSAQMKAQELYRKVDTPFEIYPGYSKDAFDYIIFYIFILLIICVAITAPTF
                     SGEYQTQSDSILRCTKHGHTRLAFTKILALFSIFIVMFVVCISIHLAISDLAFGTECL
                     KTSFQMLFSVISLVNINLLQAQILIAIGGLISILAMVSLTLFLSAKCKDSLTSMLIAF
                     SICLIPMGIGVSWIGYLLPPGGIGLKISLLYQMTSFNFLHLGGMSFWTPHIILFFSVI
                     EIPIFIFLAIRTYCKHQVS"
     gene            complement(11624..12511)
                     /locus_tag="PC366_002125"
     CDS             complement(11624..12511)
                     /locus_tag="PC366_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577652.1"
                     /translation="MELKIEHVTKKFKDKIAVEDVCLTLTPGVWGFLGANGAGKTTLM
                     RIITDIMKPTNGKILYNGKNIYIMGAEYRNLLGFLPQEFGFPQDFSVKDYLEYIAALK
                     DVPPREVKGKINNLLEILTLSDVKNKKIIKLSGGMKRRVGIAQAMLNDPKILIMDEPT
                     AGLDPGERVRFRNFISEFSHNRVVLISTHIVSDIEYISTQNAIMKSGKILDVGTTDKL
                     VKKVEGKVWECLISNRDISKYEMNLRIINQRSEKNNQVSIRYLAEKSQIDNSIAVEPR
                     LEDLYLWLFPEAVYSKEGK"
     gene            complement(12656..13771)
                     /locus_tag="PC366_002126"
     CDS             complement(12656..13771)
                     /locus_tag="PC366_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2577653.1"
                     /translation="MKKINNFTYRKLRDKYKFIKREKNTEAYLKYKLYIMLAIYTGIV
                     LVLMFMADYTFSNFSNPLVKWLKLRRDVLFFLVFIIGYITIFNFYWKKPWNYLREIIN
                     ATHTIYQQNDELVELSKPLKEIEQQMNQIKMSVLLSQQAVKEAENKKNNLVMYLAHDI
                     RTPLTSVIGYLSLLKEIPNMDNSQKSKYTEVALDKAQYLEKLINELFEITRYNSNQIK
                     INFEKVDLYYMLLQLKDEFYPLLSEKGNRAILKANESLTIKADSEKLARVFNNILKNA
                     IAYSYPNTEIIISAVHKDSKVDIAFRNYGQTIPEEQLSAIFEKFNRLDEARKSDMGGA
                     GLGLSIAKEIINLHGGDITVQSKDEVTTFTISLPTSI"
     gene            complement(13807..14505)
                     /gene="vanR"
                     /locus_tag="PC366_002127"
     CDS             complement(13807..14505)
                     /gene="vanR"
                     /locus_tag="PC366_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanR-ABDEGLN family response regulator
                     transcription factor"
                     /protein_id="HDF2577654.1"
                     /translation="MSGKILVVDDERDIADLIEVYLTNENYIVYKFYSGLDALNCINL
                     NEFDLAILDVMLPGVNGFSLCQKIREKYTYPIIMLTAKDEETDKITGLTLGADDYVTK
                     PFRPLELVARVKAQIRRYKKYSGSLQSGEELSHIFSFLGLELNTQTYECHLNGKALSL
                     TPTEFSILHVLLKNKGSVVNSENLFHAIWKDEYYNKSNNTITVHIRHLREKLGDTVDE
                     AKYIKTIWGVGYKI"
     gene            complement(14887..15567)
                     /locus_tag="PC366_002128"
     CDS             complement(14887..15567)
                     /locus_tag="PC366_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2577655.1"
                     /translation="MQTKILIIDGDKDNCQKLKGFLEEKEISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILTDGDGWTLCKKIRNVTTCPIVYMTYINEEQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            complement(15617..17632)
                     /locus_tag="PC366_002129"
     CDS             complement(15617..17632)
                     /locus_tag="PC366_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2577656.1"
                     /translation="MKKYNILKGTLIVLIVSLLAIAGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGN
                     QSPYGNATYRMRIKNEGEDKLLSLELPEIFSASEVWINGEIVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKDTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKLYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDSSY
                     FMVVLCIICINGSISKIEEDKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFIIVILFSLMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KKFLADVAHDLKAPVSAIQSFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNDFIKEIYENNLPDTQACGVNFETYILEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKVSDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            complement(17704..18381)
                     /locus_tag="PC366_002130"
     CDS             complement(17704..18381)
                     /locus_tag="PC366_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2577657.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVERI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     regulatory      complement(18961..19044)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(19277..20119)
                     /locus_tag="PC366_002131"
     CDS             complement(19277..20119)
                     /locus_tag="PC366_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2577658.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCSSNSGGSGDSGDSSKVSVSGS
                     TSIGPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSA
                     GLKETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREE
                     GSGTRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSL
                     KINDVEATDANVMANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFI
                     KVNQ"
     gene            complement(20371..22155)
                     /gene="pepF"
                     /locus_tag="PC366_002132"
     CDS             complement(20371..22155)
                     /gene="pepF"
                     /locus_tag="PC366_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDF2577659.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYTKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEKYL
                     KVIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLIHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGEPLTADEFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            complement(22221..22886)
                     /locus_tag="PC366_002133"
     CDS             complement(22221..22886)
                     /locus_tag="PC366_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDF2577660.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            complement(23037..23198)
                     /locus_tag="PC366_002134"
     CDS             complement(23037..23198)
                     /locus_tag="PC366_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HDF2577661.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            complement(23276..23785)
                     /locus_tag="PC366_002135"
     CDS             complement(23276..23785)
                     /locus_tag="PC366_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HDF2577662.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            23991..24209
                     /locus_tag="PC366_002136"
     CDS             23991..24209
                     /locus_tag="PC366_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2577663.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            24227..26173
                     /gene="feoB"
                     /locus_tag="PC366_002137"
     CDS             24227..26173
                     /gene="feoB"
                     /locus_tag="PC366_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF2577664.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIMEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKSNTH"
     gene            complement(26333..27388)
                     /locus_tag="PC366_002138"
     CDS             complement(26333..27388)
                     /locus_tag="PC366_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2577665.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKRANLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGTISSEKYNEEINKILDAINRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGVDPSV
                     PKDTRFHMKLGSKKLNK"
     gene            complement(27436..28236)
                     /locus_tag="PC366_002139"
     CDS             complement(27436..28236)
                     /locus_tag="PC366_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2577666.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     KVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFLIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            complement(28229..29020)
                     /locus_tag="PC366_002140"
     CDS             complement(28229..29020)
                     /locus_tag="PC366_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2577667.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMFDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTTLINAIPKVILDGLGVAGTLLPAVGFALLMDMLISKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAMNTLTEGEIDFE"
     gene            complement(29060..29482)
                     /locus_tag="PC366_002141"
     CDS             complement(29060..29482)
                     /locus_tag="PC366_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HDF2577668.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLANIEYFCMTKDKSADDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSIFL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENRNKIKNVM"
     gene            complement(29498..29977)
                     /locus_tag="PC366_002142"
     CDS             complement(29498..29977)
                     /locus_tag="PC366_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2577669.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTRDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKEIGDLGIDIELRMLPRDKKKQLSDLIK"
     gene            complement(30109..32865)
                     /locus_tag="PC366_002143"
     CDS             complement(30109..32865)
                     /locus_tag="PC366_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2577670.1"
                     /translation="MRDEILSFVNECVLFNNFDELKKESGIITEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYDNSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSKFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNTILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEIFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALESKL
                     LIYLKKESYKEYSIISKISTLITNRLDMYLNNVDTIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKNKINGPMLFIDQISTISALEVGNLLMQGKNIEQIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGTAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVMAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLPNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
BASE COUNT        10669 a         5834 c         3669 g        13008 t
ORIGIN      
        1 tatataaaga aaaacataca aaaagtatag aatatatact ttttgtatgt ttttactaat
       61 tcttatattt attttatttt agattctaaa tttgttaatc tttcctcaac agatttaatc
      121 atctcttcaa atttttcttt ttttactttt tcttcttcaa ttaaactttc aggagctttt
      181 gctaagaaac cttgatttgc aagctttcca ttaactctct ttatttcgcc ttctaacttt
      241 ttcttttctt tagacaatct ctcaatttct ttttcaaaat caactaattc attaagaggt
      301 ataaatattt caacaccatc aataactact ccaactgcat cttctggaac attagattta
      361 tcttttgcta tctctacatt tgaagcagat gctagagtta taaaatagtc tttaccaagc
      421 tcaatagctt ctattttttc ttcacttggg attattatca atttagcttt cttagaaggt
      481 ggtacattca tttctgctct cacatttctt atacttctta taccttccat caataagttc
      541 atcatatctt cttcttcagc catgttatct tcttcattat attttggcca ttcagatact
      601 attatacatc cttcaacagt aggaagatga gtatatattt cctctgttat aaatggcatg
      661 tatggatgta ataattttaa tattttttca agaacataag ttaatgtata taatgctgca
      721 gatttagcat ttgcatcttc cccatataat ctaggtttaa ccatttcaat ataccagtca
      781 cagtattctg accaagtaaa atcgtatatc ttttgaagtg ctattcctaa atcaaactta
      841 tccatgttat tagttgcttc ttttacaata ttatttgctc ttgatattat ccatttatca
      901 gctagagtta agtcctcttt aacactttct ctagtcatgt ttttaattat atcttcatca
      961 atattcataa atacaaatct tgatgcattc cacaacttat ttgcaaagtt tctagcaaat
     1021 tctactcttt ccatatagaa tctcatatca tttcctgggg aatttccagt tgttaatgta
     1081 aatcttaggg catcagctcc atattgctcg attatctcca atgggtctat accatttcct
     1141 aaagatttac tcatttttct accttgagaa tctcttacta atccatgaac caaaacatgg
     1201 tcaaatggct tttcattcat acagaacata cctgcaaatg ccattctaac tacccagaag
     1261 aatattatat cgtatcctgt aacaagtaca cttgttggat aataataatc taaagcttca
     1321 gtcttatttg gccatcctag agtagagaaa ggccataatg cagaactgaa ccaagtatct
     1381 aaggcatctt catcttgttt aaaatgagtg cttccacatt taggacactt atctggcatt
     1441 tttctagcaa ctactatttc tccacactct tgacaataat aagctggtat ttgatgaccc
     1501 caccataatt gtcttgatat acaccaatct cttatatttt ctagccattg taaataagtt
     1561 ttatcaaatt tatctggaac aaattctaat tctccttttt taagaatatc tatagctggt
     1621 tttgcaagtt cttccatctt aacaaaccat tgctctgata atctaggctc aactactgta
     1681 tggcatctat aacaagttcc tacattatga ttatgcgctt ttatcttaat taggtaacct
     1741 tgttctttta agtctgctac gatagctttt ctacactcaa atctatccat accttcatat
     1801 tttccacaaa cttcattcat agttccatct tcattcatag tatttaactg ctcaagatta
     1861 tgtcttaatc ctacttcaaa atcattaggg tcatgtgctg gagtcatctt aactgcacca
     1921 gttccaaact ctaaatcaac ataactatct gcaactattg gaagttctct tcctactaat
     1981 ggaagtattg ctgtttttcc tattaaatgt ttatatctat catcttctgg atttactgct
     2041 ataccagtat ctcctatcat tgtctcaggt ctagttgtag ctatttctaa aaagtcttca
     2101 ctatctttta gtgggtactt tatatgataa aagtttccgt cgtgttcttc atgttcaact
     2161 tctgcatctg ataaagtagt tttgcaatct gggcaccagt ttattattct atttcctctg
     2221 tatatgtgac ctttttcata taggcttaca aaaaattcta taactgcttc attacaccct
     2281 tcatccatag taaatctttc tttatcccaa tcacaagaat cacctagttg tttaagctga
     2341 ttagatattt ttcctccaaa ttcatctttc cattcccagg ctctctttaa aaattcttct
     2401 ctacctattt catactttgt cttgccttct tgttttttta ttctttcaac aactttaact
     2461 tctgttgcta tagaagcatg gtcagttcct ggaagccaaa aagcttcata tccatccata
     2521 cgtttccatc tgattaatat atcttgaagt gtatggtcaa gagcgtgtcc catatgcaat
     2581 tgccctgtta tatttggtgg tggcatcatt attgtaaatg gttttttatc tggatttggt
     2641 ttagatttaa aatacccttc atccatccat tttttatata gcctagcctc aaaatctttt
     2701 gggttataag tttttgataa attcgtattt tccattgtcc tgcctcctgt attttataaa
     2761 taaatttttt aaatatcttt agaaataaaa aagagctctt catcctcttt aaaaaggacg
     2821 aaaagctcgc gttaccacct taattccaaa gcttaaaata cattaacata taattaaatt
     2881 attagttaat gttattttat caactttgac tctcaaagaa tttaacggtt ctaaccgtct
     2941 aaacttactt atagttcagt ttagaaactc caaagctaca ttcagtaaat cttatactta
     3001 gaaaatctta cagccagtga attttcctct cttttagtag tatttactta ctcctcttct
     3061 tctcagtctt taatattaca tattattata tacaaatatt attctctttg tcaattattt
     3121 ttattttatt ttttctgaat tttcttaatt atgtctattc tcttttatat agttgttata
     3181 ttttaaaata tgtttttaca gttattctgt cttataatgt caataattgc aagattattt
     3241 tattttaatt ttaatgcttt ctcattaatt ttatattata ttatccttac agtatacctc
     3301 ttattcgtat tttttatatt atatgtttta ttttataaat aatttacttt atcttttact
     3361 atatttaaat ttattataag ttttcttgcc agaaattttt aggtgttata ttttctgtaa
     3421 ttggcaatat tgtatatcct ctctctttta agattcttat aatattattt aaagcattta
     3481 aactttgctc tttctcatga attaatacta ctaattcatc tctttttctt ccataatata
     3541 atatattact tactatctga cttgtagaag acttccaatc ctgtgtatcc aaattccagt
     3601 cccaaattaa ataatcattt gccataagtt tattatatga accttctggc atatatggtt
     3661 tacttccgta tggtaatctt attaattttg aactctgacc agttatttct tgtagagtat
     3721 tattgcatgt attaaattcc ccaactgtta cttctgggct tttatataac ttatgtatat
     3781 catgacttac actatgaaaa cctattgagt tttcctcttc caagactctc cttacttctt
     3841 ccttgtgatt tttcatattt tgattaagca taaaaaatgt cgctttgaca tcattttctt
     3901 ttaaaatatc aagtagtgca tttgtatatt ttgatggacc atcatctatt gttatgtatg
     3961 ctactttttc agaagtagcc cctggacctt ttgtttcttc ttgagatgct ttgtatatga
     4021 tttctcctaa agtattactt tgagaaagca gttccagtgt attttcacct tttgaactta
     4081 tattttcaac tggaacatta ttaatttttt cctccaataa tgttccagtt aaaattaaaa
     4141 cagctataag aaatatcctt ataaatacat gaaaaacagc cttattatct ttaattttca
     4201 tcccccatat ctccctttta taaaagcata agtttaagac ttaaaaagtt attttttata
     4261 tttattctct ttcttattac tttttatatc tctactaaat atttttttaa ccttttcttc
     4321 ttctttttct cctaaagatt ctactctttt gattcccaaa gaagttaaaa attgtaatac
     4381 atttaaatta tcaaatggag tttccatatt cgtactttca ctatattcat caacattctt
     4441 agtaccttct tccacactta aaatacgctt cggacctcct acacagcctc ctacacaccc
     4501 cattccttct ataaatgtag cttctatttc tttatttaga actttcttta gaccgtccat
     4561 gcactctttt gttccttcaa atgccttttc ttcaaatttt atatttttgt caattcttct
     4621 gactgataac ttaactgctt tacttacacc tcctgttcta gcataaactc tacctgaaag
     4681 ggacgcctct actctattac tctcatccat tattgctgga tttaactcta atgcatcaaa
     4741 tatttcttgc aactctttaa atgtaagcac aaaatcaact gcatctttta tatcttctaa
     4801 cattgcttct ttcttttttg ccatacaagg acctatgaat acaactttag catctggatt
     4861 taaaattttt acagctctcc cacaagcaat cataggagaa acggatggtg atacattctc
     4921 caatatctga ggaaaactat tttgtatcaa actaacccaa ataggacagc aacaactagt
     4981 tataaagcat ccttcttcgt cctttttcat atgctcataa taatcatatg cttcttttgc
     5041 agtaagcata tctgctgcca aagcaacttc tatcatatct tcaaatccta tcttttttaa
     5101 tgcagttctt aatttaccag ggcttacatc tttcccaaac tgtcctacaa aagctggtgc
     5161 aactattgca tatacagggc tctttatatc ttttaacaat tttatcattg gtataaattc
     5221 tattttatct gaaattgcac ccaacttaca tcttgataca caatcaccac aagcactaca
     5281 tacatcttcc tcattacaat taatatgctt acttcttatc ttacatgact catcttcctt
     5341 attattttca tcacaatatt tgcaagcatc tgatattaca gatattattg gtcttttgac
     5401 ttcatctaaa tttacagctt catgtagtga ctcttttaaa tttttatctg tatcttctgt
     5461 cacatccaat cccatagtta ccctaattaa atttaccata gtatctttat caaattttcc
     5521 actaaaataa ttatttaaat tatcctttaa atcttcattt aaaattttat taggtaagtt
     5581 ttcaatatcc tctatatcat cattccacac tgcttttaca agttcgccaa aaagcttcat
     5641 tttatatatt tctagtattt tagaattgtc atttctagta ttcataaaaa atagtacctc
     5701 cataaattaa acttatatat gtttaatatt tacaaagata ctatttttta tttattattt
     5761 aactactatt attaatatga tttatttagc tttctcaaca actctatttc aatcattatt
     5821 ttcattagat gatagttgaa tacggggctt ttttcttcat ctatattcca gtctagctta
     5881 tccacattat atgttttctt aaggtattta tatgtatgct ctttcaaata aagtttattt
     5941 tcaagtaact ctatagactg catatgaaaa tgtatttctc tacatatcct taaggcattc
     6001 tcaatttttt ctatattagt ttcactcaaa ctataatcca actcatcaat aagttttgaa
     6061 tatatttctt ctaatttttc tacttcttct tcaaatttct ctacatttaa attttctttt
     6121 ctaagaattt tatcttcaat aagtaacatt gaaagttctt ctatcttttt aaattcatct
     6181 ataacactat ttagataatt tggtctagcc acataataat taacaagtac tccaaacaaa
     6241 acacctacag atgtatctaa cactctatgt aaagaataat acacagggtc actatttcct
     6301 acacctagat gtatagccag aaaggttaca caggcaacta ctactgactt tattttaaac
     6361 agattgcata aatatattga gcacattact cctagaccac ataaaaaagg gtctccagct
     6421 ttaatgatgg caaatatgaa tcctattata ccacctaaaa tagtaccttc cactctattg
     6481 attcctgtct ttaaagaacc ttttaccgta tcttgaacag aaattataca tgctactaga
     6541 gaataaaaca tattctctac tagatagtta ccaagaatca tacataaagt gacactaatt
     6601 cctgttttta tagtcctcat acccatcttt tgaagtttca aagttccacc tcctaaaaag
     6661 caccttatat aaaatacgca tcctcatatt taatatgttc ctagtatatc acaatttttt
     6721 aaatttaccc attaatcata tttttttatc aattctttct taatttagac aataaaaaaa
     6781 ctgctttaaa gcagtttttt atcctatctc aaccatttta ccctcaattg caaaaattat
     6841 cttctcacat acatttgtta tatggtctcc aattctttca aggtatcttc ctataagtag
     6901 aagttttact ccttggtcta tagtatttga attttcatgc attattttta aacaatcaat
     6961 ttgtacttgt tcatacaatc catctacaat atcatcttta gttccaacat cataagctat
     7021 acttgcatca aataagatta aagcttctct agtctgagac atcatagact tacattcttt
     7081 tgccatctta ggaatatcta tcagctcttt tatataagcc tctccaccta tcttcaacat
     7141 ttctctagct atatttgctg cataatctcc tattctttcc aactctatcg atatattacc
     7201 taatgaataa ataaatctta agtcccttgc cattggttgc tttaatacta ttagctctat
     7261 actcttatct cttatttctt ctcttaattt atttatttct tcatcatctt ctactacttt
     7321 tcttgcaccc tctaaatcct tctctatcat acaagtcaca gacttttcta ttgcttcttc
     7381 acatttttcc atcataagta ctgtttgttc ttttaaagta tcaatactta tatctaaact
     7441 attattgacc attgtctaac tcctttatag ttatatattt taaccaaatc tacctgttat
     7501 atagtcttct gttcttttat ctacaggagt ggtaaacata gtttttgtat cgctaaattc
     7561 tataacctct ccatttaaga aaaaagctgt ttcatctgat atacgagcag cttgttgcat
     7621 attatgtgta actatgacta ttgtgtagtc tttttttaaa tcctctataa gttcctctac
     7681 ttttaatgtt gaaattgggt ctaaagcaga tgtaggttca tccataagaa taacttctgg
     7741 tctcatagca attgctcttg ctatacatat acgctgttgt tgaccaccag aaagtcctag
     7801 tgcagatgat ttaagcctgt ctttaacctc atcccaaata gctgcacctt ttaagctttc
     7861 ttctacaatt ttatctaatt gcttcttatc tcttagtcca tgtgtacgag gaccatatgc
     7921 cacattatca tatatactca taggaaatgg atttggtttt tgaaatacca ttcctacttt
     7981 agtacgaaga tttataacat catctgaggt atatatgtcc tctccatcaa cagaaatgtt
     8041 tcctttaatt gttacatctt cgattaagtc attcattcta tttaacgttc ttataaaagt
     8101 tgattttccg catccagatg gacctattaa agcagtaacc ttattctctt ttatatccat
     8161 atttattttc tttaatgctt gcttatcacc ataaaataaa tccaaatctt ttacactcat
     8221 ttttatctta tcgattaatt ccattattca cacctcttaa atttaataat tagctttatt
     8281 taatttctta gcaacaaatc ttgctagcat gtttagtgct aatacaatta ctattaaaac
     8341 aattcctata ctggctgctg ttgctatatc tccactctct ttagtcagta agtatgagtg
     8401 tacagttaat gttcttgcac tatcaaatat tccacctggc atcttggcta cagtacctgc
     8461 tgtaagtaat attgcagctg attctccaat tatacgacca actgataaga ttactccaga
     8521 taagattcct ggtattgcac ttggaagtac taccttatat aaagtttgaa attttgtagc
     8581 tcctaatgcc aatgatgatt ctctataagc ttgaggaact gtttttaaag cttcttctgt
     8641 tgtacgaatt attactggta atattattat tgcaactgta agtgaacctg caactatgga
     8701 atatcccatt tttaatgtaa ctacaaagaa aattcctcca aataatccat atactataga
     8761 tggtatccct gataaacttt cagttgcaaa tcttatagct gtaactgctt ttcctttttt
     8821 agcatattct tgtaaatata tagcagccaa tattcctata ggagttgcta caactataga
     8881 aactactact gtatataatg ttgtaattat cattggaagt ataccaccat cacctgatgc
     8941 tgaataattg ctaaataaga aattaaaatt catgttgcca attcccttta taaatataaa
     9001 tcccactata atgactaatg atactattgt aaatagtgct gatagatata ctaatgactt
     9061 caatagattc tctttgaact ttctcatctt aatttaccgc cttatttgaa agtttattta
     9121 aaactaagtt taaaattaat ataaatgtaa acaatactac tccagttgca aataacattt
     9181 cttgatgtgt accaaatgcg tatcccattt caagtgctat attagttgta agtggtctta
     9241 cactatctgt tattgcagtt ggcataactg gtgagtttcc tgcaacaagt attactgcca
     9301 ttgtttcacc taaagctctt cctactccta atactactgc agctaatact ccagatttcg
     9361 cagcaggtag tacaactttg aatattgttt ctatttttga tgcaccaagt gctaatgaac
     9421 cttctttgta tgcttttggt actgctctta ttgctgtttc tgatacagat attattgttg
     9481 gtaacatcat tactgctaat actattacta ttgctaacaa actttgacct tttggaagat
     9541 taaatatact ttgtatagtt ggaactatca ctgcaagacc aaatacacca tataatactg
     9601 aaggtatacc tgctaaaagt tcaactgctg gtgacattat ttttgctaat cttttaggtg
     9661 ctacttctgc tataaataca gaggttaata taccaacagg tactcctatc acaagtgctc
     9721 caagtgttgc aaatattgat gctactatca tagatgatat tccaaattta ttggcagaag
     9781 gaacccaatc tgcaccagtt aaaaagtcta taaatgaata tccttcaaat ataaatggtc
     9841 ttaagccttt ataaaatacg aatcctatta tcaaaagtaa acttgcaact gctactaaag
     9901 cactaagtag aaaaatattt tttgctactt tttcaattac gtattttgtc ttattgccat
     9961 tattgtcatt tttttctaaa cctactaatc tagattttac tatcataata ccctcccatt
    10021 aaaatatact tatcgatttt cgttctgtat tcaaaattta attttttata attcgtcttc
    10081 atcaaatttc ctgtactttt attctacttt ttttaagtta aatctatatt aggattaagt
    10141 taagcaagtg taaaattata tttacttttt taacattaat tttactttta aaactatatt
    10201 tgacatttac tttacaatat actgttgttt ctctatatta aaatagcaga tatagataat
    10261 aatacagttt atgtataatt tattacctat atctgctatt aagatttgtt aactaaattt
    10321 aacttttata ctacatatat aattatcgta tcctctagtt tatatcacta ttatttctat
    10381 caaattgtta tgatacttga tgtttgcaat aggtacgaat agccaaaaat ataaaaatag
    10441 gtatttctat cactgagaaa aacagtataa tgtgtggtgt ccaaaaactc atacctccta
    10501 agtgtaagaa attaaatgat gtcatttgat ataataaact aatcttaaga ccaattcccc
    10561 ctggtggtaa taggtatcca atccaactaa cacctattcc cataggaatt aagcaaatag
    10621 aaaaagcaat cagcatagaa gtaagagaat ccttacattt tgcagataaa aataatgtta
    10681 aactaaccat tgcaagtatt gaaattagac caccaatagc tataagaatc tgtgcttgta
    10741 gtaaatttat atttactaga ctaatgacag aaaacaacat ttgaaatgag gttttcaaac
    10801 attcagtacc aaaagctaaa tcagaaattg ccaaatggat agaaatacat acaacaaaca
    10861 ttactataaa tatagaaaat agagctaata ttttagtaaa cgctagacga gtatgtccat
    10921 gtttcgtaca acgaaggatg ctatctgatt gtgtctgata ctcaccagaa aaagtaggtg
    10981 cagtaattgc aacacatata attaataata taaaaatgta aaatattata taatcgaaag
    11041 catctttaga ataacctggg tatatctcaa atggagtatc tacttttcta taaagttctt
    11101 gagctttcat ttgtgcactg gaagtttgtc gttcaatctt cataatatca tttaaatgag
    11161 ttttgcattg ttcataaaaa gaatctaaat catttgtatt tatttctgat aattctgttg
    11221 caaatcctgt ttctgaatta gcaaatgctt caggaagtct attcaacaat gggcgtattg
    11281 gtaaaatact tttagaataa atatctagtg ggaaatcttc actacctact ttaccatact
    11341 tttcttctgt ttttttccat atatttaaag catgctttaa tttttttggt gttacaactc
    11401 cactactaat ttcactatta ttagcataaa ttgttttttt atatttaata gcatctaaac
    11461 cactcaattc aactaccttg ccattattat ctaaataatt gataccctcg taagtaattg
    11521 gaagaaaagc catcaatgca gataaaacca atgccaacaa taataaaatt aatgtacgac
    11581 gtgagtgcaa cactcgttta atttccaaat aaaaaatacg catttatttc ccctccttac
    11641 tataaactgc ttctggaaat aaccataaat ataaatcttc tagtcgtggt tcaacagcaa
    11701 tagagttatc aatttgtgac ttttctgcca agtaacgaat agatacttga ttgttttttt
    11761 cactacgctg attgattata cgtaaattca tttcatattt tgaaatatct ctatttgata
    11821 taagacattc ccatactttg ccctctactt tcttaaccag tttatcggtt gttcccacat
    11881 caagaatttt tccacttttc ataatagcat tttgagttga tatgtactca atatcagata
    11941 caatgtgagt agatattagg acaacacgat tatgagaaaa ttctgaaata aaattacgaa
    12001 atctcactcg ctcaccaggg tcaagccctg ctgttggttc atccattata aggattttag
    12061 ggtcatttaa catggcttgt gcaattccca ctcgtcgttt cattccacca gataatttaa
    12121 taatcttttt attttttaca tcagataatg taagaatttc caatagatta ttaatttttc
    12181 cttttacttc tcttggtggt acatctttca atgctgctat atattctaaa taatctttta
    12241 cagaaaaatc ctgtgggaaa ccaaattctt gtggtaaaaa tcccagtaaa tttctgtact
    12301 cagcacccat tatataaata ttttttccat tatacagaat tttgccattg gtaggtttca
    12361 taatgtctgt aataattctc atcaaggtag ttttacctgc tccgtttgct cctagaaatc
    12421 cccacacacc tggtgttaag gtaaggcaaa catcttctac agcaatttta tccttaaatt
    12481 tttttgtcac atgttcaatt tttaattcca tatttgaaac tcctctcttt atctacttac
    12541 ctgcaaaaac aaaagtgtct tgcttagtat ttattttact aaacaaagac actcataatt
    12601 ttaatattaa atagataatt tcttaagaaa atcctaatat ttgatttata ttttactaaa
    12661 tagatgtagg aagcgatata gtaaatgttg tgacttcatc tttactttga acagtaatat
    12721 caccaccatg caaatttata atttccttag ctatagaaag ccctaaacct gcaccaccca
    12781 tatcagattt tctagcttca tctaaacgat tgaacttttc aaatatagca gaaagttgtt
    12841 cttctggaat tgtctgtcca taatttctaa aagcaatatc taccttgctg tctttatgaa
    12901 ccgctgagat aataatttct gtattaggat agctgtaagc aatagcattt ttcaagatat
    12961 tattaaacac tcttgcaagt ttttcagaat ctgcttttat tgttaaactt tcatttgctt
    13021 ttagaatggc tctatttcct ttttcagaca gcaatgggta aaattcatcc tttaattgaa
    13081 gtaacatata atataggtct actttttcga aattaatttt gatttgatta gaattatatc
    13141 gtgttatttc aaaaagttca ttgataagtt tttctaaata ttgtgctttg tcaagtgcaa
    13201 cttcagtata cttagatttt tgagaattat ccatattagg tatttctttt aataagctca
    13261 aatacccaat aactgaagta agtggtgtcc ttatatcatg tgctagatac atcacaaggt
    13321 tattcttttt attttcagcc tctttcactg cttgttgact taacaaaaca gacatcttaa
    13381 tttggttcat ttgttgctct atttccttta atggcttaga tagttcaacc aattcatcat
    13441 tttgttgata aatagtatgt gttgcattga tgatttctct taaataattc catggttttt
    13501 tccaataaaa attgaaaata gtgatatatc caattataaa aaccaaaaaa aataatacat
    13561 ctcttctcaa cttaagccat ttaacaagag gatttgaaaa atttgaaaac gtataatcag
    13621 ccataaacat taaaaccaat actatacctg tatagatagc taacattata tataatttat
    13681 actttaaata cgcctctgta tttttttctc tttttataaa tttatattta tctcttagtt
    13741 tcctataagt aaaattatta atctttttca taatactaca tcccttcttg acaagaaaaa
    13801 taggtgtcaa atcttgtaac caacacccca aattgttttt atatattttg cttcatctac
    13861 agtatcacct aatttttcac gaagatggcg aatatgaact gttatagtat tgttactttt
    13921 attgtaatat tcatctttcc agatagcatg aaaaagattt tctgaattta ccacagagcc
    13981 tttatttttc aataatacat gtagaataga aaactctgtt ggagtaagtg aaagagcttt
    14041 accatttaaa tggcattcat atgtttgggt attcaattcc agacctaaaa aagaaaaaat
    14101 atgtgaaagt tcttcaccag attgtaaact tccactgtat ttcttatatc ttctaatctg
    14161 tgccttcact ctagcaacaa gttccaaagg tcggaaaggt ttagtaacat aatcatctgc
    14221 acctaaagtt aagcctgtaa tcttgtctgt ttcttcatcc ttagctgtta acataatgat
    14281 tggataagta tatttttctc ggattttttg gcataaagaa aatccattta ctcctggcaa
    14341 cataacatct aaaattgcaa ggtcaaattc atttaaatta atgcagttta gtgcatcaag
    14401 accagaataa aatttataaa caatatagtt ttcatttgta aggtagactt ctattaaatc
    14461 agctatatca cgttcgtcat ctacaactaa aatttttcca ctcatagact ttaaacatcc
    14521 tttctatata tatttatata tattatacta aatttaattt ttttatatga ttttttacat
    14581 tagaatttat taagaaattc ttaatcttat tatgtaacta ttttattatt taacatatat
    14641 taaagataaa aatgaatata tatagattta gatatacaat ttatctatct tttcaaatat
    14701 aatctataaa ataatagttc tgttacgcat tttttcatat aataaaactg actgtaattt
    14761 aactggcaaa gtctagaaga ataggcttta tcaattaaat tacagtcagc tattttataa
    14821 taatttagtt tagatatcgt tagcatttca catttataac aattattaat gagattaata
    14881 tatttattat tctttattaa aataatatcc tgctcctctt attgttataa ttttctgagg
    14941 atttttataa tctttctcta ttttctttct taatccattc actgcaacta ccacactata
    15001 gttatcctct aagtactcat tcatccatac atgttcatat atctctttag tagtcagagt
    15061 cttttcagga ttctctataa aaaagtttaa cagcttattt tctgttggag tcaattttat
    15121 tattttgtct tctaacttta ttactccact agttctatta tattcctcta attttgtatt
    15181 attttcatta ttatttacat atgagttcat tcttcttaaa atagctttta cttttgcata
    15241 taatatttct aaatttagag gctttattaa gtaatcatct ccgccagaat ttaaagcatt
    15301 taaaatgctt tgttcttcat ttatataagt catataaaca attggacaag tagttacatt
    15361 tctaattttt ttacaaagag tccatccatc accatcagtt agaattattt ctaaaaatat
    15421 taaatcatat ttattgctaa atatttttcc aatagcttct tcacaattat atgctaaatc
    15481 tatacttatt tctttttcct ccagaaatcc ttttagcttc tggcaattat ccttgtctcc
    15541 atctattatc aatatcttag tttgcattat aatcactccc aaatatcatt attcttttat
    15601 attaaataag ctattattat aaaaaacata gacttaattt tattgtaaaa acagttcctt
    15661 ttcctagttc tgaatctaca aagatttctc cgccatgctc tcttataatg gatttgacaa
    15721 tatataaccc tagcccttgc ccttttggct cattattatc tctttctgta aagaatctgt
    15781 caaatacctt tggtatattt tctggaggta taccttttcc attatcagaa actttaataa
    15841 ttgcaaatcc atcttcttta tccattgata aaattatctt tccatcaaat ggagtaaatg
    15901 tcaaagcatt ataaattaaa ttctcaaatg ctcttgtaag catctcttta tttatctttg
    15961 catatatttt tttctccaat atgtaagttt caaagtttac accacatgct tgtgtatctg
    16021 gcaagttatt ttcatatatc tctttaataa aatcatttag acatattttt tcactaatac
    16081 caatgctttt atcttgtgat gtaaattctt gcaaactacg tactctattt tgtacttcat
    16141 ttgacttttg atttatagca taaagatagg ttcttgtctc ttcatctaca tgaatattac
    16201 caacctttat caagtctata aatgattgta tagctgaaac aggtgccttt aaatcatgtg
    16261 ccacatctgc caagaatttt ttacgttcat ttaacaatgt tgtaagttca ttagttctca
    16321 cttcaacttc atgttcaaga ttccttgtaa gtttttcatt ctcttttatt attattctat
    16381 tcctgtttat catcataaga gaaaataaaa taacaattat aaatccacaa tattctgttt
    16441 gccaccctgt aaatataggc tcaaatctat tactagtaac tgcatcaaat aatatgctaa
    16501 ttccaaaaac agtgtttact gaaactaaaa tataagaact tatatgctca gagcatgtct
    16561 ttttatatat tgaaaccagc gaagacatta atatatatat aaatacaata tatttatata
    16621 tgtctattaa tttcccatat atgttgacaa agtacatatc atatggaaga agaataattg
    16681 gtatcactat agatatgata ctcattgtaa ttcctaatgg taaaattaaa aatctataca
    16741 ctttatcttc ttctattttg gatatacttc catttataca aataatacat aaaactacca
    16801 taaaatagga cgaatcttca accgcatatg taaagcttac caaaggcagt cctaacaaat
    16861 gtacaaaggg ataggataca tggatggcaa agaaaacaca catacatcca aaatataagt
    16921 aaagtttact tttgtttgaa agaaaccata cagacaacga aaatatagct attgcaaaag
    16981 ttgtgaagca aattatacta taaaaaagta atcgataaaa catcatatta cttatgtcct
    17041 ttgtttctcc taatgcaggc ggataataca aaccactata ataatgtgaa aaattcgata
    17101 cattgattat aatttctgta tctttctttg caataaaact tactactgaa tttttaattt
    17161 tgggtctata tttttctgtt cctacatctc ctaatttaga aactatttct ccatttatcc
    17221 atacttcact tgcggaaaaa atctcaggaa gctctaaact tagtagctta tcctcacctt
    17281 cattttttat tctcatacga taagtagcat tcccatatgg tgactgattc ccttttctca
    17341 tagaaaaatc tggatattga cctataaaaa catattctgg ttttatatct tgctctgtaa
    17401 aatcattcgg tttaaatatt ttatgattat aaaactccca gtcatctatc agaaagacaa
    17461 gtttaccttt agtgaaagta tcattatcta tagttaaaat tccattactt gctctaatag
    17521 acttatatgt atatttatta tcatatttat acagaagatt taatcctgct attgccaaca
    17581 gagagactat caatacaatg agagttcctt ttagtatatt atactttttc attgcatcaa
    17641 ccacatctct ttcatagtag tattaaataa aacaagaact atttattaat tacagtatct
    17701 cacttatggt acaaacttat atccttttcc ccatacggtt tgaatgtatt gatgctccct
    17761 gcttaaagaa ttaatttttt ttctcatctg tgcaatatga acctgcactg tatgttgatc
    17821 tccaatatca ggcattttcc aaacttggtt atatatctct atcttcgaaa atacttgttc
    17881 tttgttttca gctagaaaca ataatatttc aaattccata gtagttaaat ctatactttc
    17941 tccatcaaaa gttacttttc ttgaatttac atttattact aacgctgaaa actttaacac
    18001 attaggaact gatgtaatat ttttgtactg cctcatacga gcatatattc taagttcaag
    18061 ttcttttaaa ctataaggtt ttgttatata atcatccccc ccagctaaaa atccccgaac
    18121 tttttcttct tcatgctcat aattagataa aaatattata ggtatgttaa ccttttcttt
    18181 tatatcattg cacattttat atccatctat atctggcaat gaaatatcca aaattataca
    18241 gtctaaaact atacgctcta ctatatccat agcatcttta gcagtctctg atgtatatac
    18301 attaaaacct atattagaaa aataaatttg atttatattt aaaatatcaa catcatcatc
    18361 tacaaccagt aaattataca ttacaccact ccattcaaag gtattttaat cataatctca
    18421 agttttataa ttattacaaa ttataatgtt ttattttcat atataactag tattattatt
    18481 ttataatatc tttacaaact agactataat acttaagtat ttttgaacaa ttcttgaata
    18541 ttgtattgaa cattaagatt tattattaaa tactaattaa agtctccgat tgttggagaa
    18601 tggagcttaa agtcattttc acttataaat ttattatttt tctagaaact tgtctattgg
    18661 ctagtttgag tattgattta tatgatttat atggttataa tataaaataa attgtattat
    18721 tttggtaaat atattgttac aaaaggttta tattttgcat ctcaatgttt ataaaaactt
    18781 tattttctta ttataatagt attatacttt ttaaaaaatt tcccttttcc aacaaatggc
    18841 tactttaaaa gccaaaattt cacctatcaa taaaaatctt aacgactaat actcttattt
    18901 tcaaattttg caacattttt gttaatttta aagcaaaaaa agactatgca atataaaaat
    18961 tatattcata gccggttgca ccactaactc catatatctc cagatgccca ataataagat
    19021 atacttctca gtttctaaaa tatttttatt aaaaatcttt tatatatttt cataaatttc
    19081 ttttttattc taacattgta atattatttt gtcaatattt ccatattttt agatataaga
    19141 tactaaaata cctattttat ctaaagatat ttatatttct acattcaata atagacaata
    19201 ccctgcaagt taaagcatca tttttatgag cttatctcac agggtattat atgtttactt
    19261 tatattataa ttcatgttat tgattaactt taataaatcc tttttctgaa acaagtgctt
    19321 gtccttcatc acttaatata taatctatta aagctttccc tttttctgac aaaccatctt
    19381 ctttattaac taatataaat ggtcttgata ttggatattt attagccatt acatttgcat
    19441 cagttgcttc aacatcattt atttttaaac tatttacttt ctcatcaaca tatccaaatg
    19501 atatatatcc tatagcattt tcatttcctt caactgtagt ttttatattt cctgaaccat
    19561 cacttatttg tgcatcttta gttagttctt ctgaatcaaa ccctacaatt tcttggaatc
    19621 catctctagt tcctgaacct tcttctcttg atactattac tattggtgca tcatttcctc
    19681 ctacttcttt ccagttagta atctttcctg tatatatacc tttaacttgg tccattgtca
    19741 ggttttttac tgagtttgca gtattagtta tcaatgctat accatctatt gctattttag
    19801 tttcctttaa tccagcactt ttttcttcat cttttaaatc tcttgaactc attcctattt
    19861 cagatgttcc ttctatggca ttttttatac ctccggaaga accaatctgt tgtacttcta
    19921 cactaacacc ttgatttttt tcttgaaact tttctccgat agtttccata agaggaccta
    19981 ttgaagttga acctgaaaca gaaactttgc ttgaatctcc tgaatcacct gaacctcctg
    20041 agttagaact acatcctact gctaaagctc caactaacat tgtactagct aaaagaacgc
    20101 ctattttctt tttaaacatt ttacttaccc ccgcttatat tttaattttt tgttgtcatt
    20161 tttctatatt ttaataatac agattctttg ttaaatgaat attagagcag ggttaagtaa
    20221 atgtaaatat tgttaaatac atgtaaaaac ttaattttat atgatttatt cttaattaga
    20281 ttaacttttt aaagttactt taggcagata taaacacaat acaactcata ttatcagaag
    20341 tcttcattga agctatcaac ctatcacatc ctataattct ttttctagtt tattaactaa
    20401 ttcagcaaat acatttaagg cttcctctat agattctttt ttagtcatat ctacaccagc
    20461 agattttaat tgttctagtg ggtattctga ccctccactt tttaagaagt ttatatatct
    20521 atctactgca gtacttcctt ctgaaagtat ctgttgactt aaagcacttg cagcagaaaa
    20581 ccctgtggca tacttatata catagaagtt tgaataaaaa tgaggtattc tcgcccattc
    20641 tattcctatt tgtttatcta ctattgcaga ttttccgtaa tacttttcat ttaatttgta
    20701 gtatatatta gtaaattcat cagcagtaag tggttctcca ctctctaccc tttgatgtac
    20761 aattttttca aattcagcaa acatagtttg tctatgaact gtagttctaa attgttctaa
    20821 ataataattt aataagtata tagtttcatc cttagactta gaattttcta ataaataatt
    20881 tataagaagt aattcattta atgtagatgc aacttctgca acgaatatct tatagtccga
    20941 atataaaaat ggttgacttg ttcttgaata atgactgtga acagagtgcc ctaattcatg
    21001 aattaaagtg aatagagaat taaggtcatt tttatagctc attaatatat aaggatgtga
    21061 atcataactt ccccaagaat aagctcctcc ttttttacct tcattatcat atacatcaat
    21121 ccacccttca tcaaaagcac tttttatgac cttcaagtat ttttctccta aaggtttaag
    21181 tgcctctaat atgatatcct gtgctttatc atatggtata tccatgtcaa atttatctgt
    21241 caaaggaaca tacaaatcat acatgtgtat ttcattcaat cctaaaaatt tctttttaag
    21301 ctcaacatat ttatttagat taggaatact tttatctata gctgatataa gattattgta
    21361 aacatctaaa cttacatcat ctgaaaataa agacgcttct attgctgaat tatactttct
    21421 agtttttgcg taaaatatct ctgattttat tccaccataa agcgttgagg caaatgtatt
    21481 tttatatttc tcatatgttg aaaattcacc ttcaaaagcg tcttttctaa ctctactatt
    21541 cttacttttt ataaataaag agtagtttga atgagaaagc ttaaccttat taccctcctc
    21601 atcttctatc tcaggaaatt ccatatctgc atatgctaac atatcgtata cattttctgg
    21661 aattgtcgat aattctgatg tagctgcaag tatttcttcc tctcgttcac tcaaagtatg
    21721 tggtttatct ctcaatatat cctttatata ttttgtataa aaggatagct tctcatcttt
    21781 taagtattca cttaacttat tctcttctat cgccagtatt tctggaacta tataagaagt
    21841 agccacacct aaatcagtag ataacatttc tgtcttagtg gctcttcctt gattatcatt
    21901 aattctagta tcttcatgtt gtttcatatg agtatataca tataaatttt gaacaatcct
    21961 agatgcattt tcagagatat ttaatacttt atataagttc tccttactct cagaaagctt
    22021 ccctttatat tcttttactt cttggataag attttttact ttacttatgt ctttttcaat
    22081 ttcctcttta ctggagtaca tcttatctat cttccatttg tacttttctt ctattgtact
    22141 tctatcagtt cccatatcat acacctctat tttaatttgt tttatatttt attcacttta
    22201 caaaatatat tgtatatatt ttagtccaaa taatctacat ttattactcc ttctatcata
    22261 tttatttctt tcataacgtc gtgtaagtgt attctcttag cataagatac aaaaaaatta
    22321 accttccagt attcttcatt acgacattct atttccatat ttcttacgat aagttgattt
    22381 ttttcaaatt tatcatataa aaaaggtata gagtccaaat tgcttaattt taatatcaat
    22441 acattctttt cttggctaaa taaaaacgta ttgattatcc taagcacaaa taatgctatc
    22501 attacaaata atccacctag aattgccaat tcataataac catatccaac tgctatacca
    22561 atacatgcag ttgcccacat cccagcagct gtagtaagcc cttttactcc acctttattt
    22621 tttaaaattg ctcctgcacc taaaaaacca attccagata atacttgagc aggcattctt
    22681 gctgggtcag catttgtata caaattataa tcaaagaata attgaatcga agttattgaa
    22741 acaatacaag aacctattgc aattagtata tgtgtcctaa atcctgcaaa ctgtcttatt
    22801 ttttctctct ctaagcctat tattcctcct attattagtg ctaatagtaa ccttattgct
    22861 atctccttac ttcctatatc aatcataata taaaaccctc ctgacttaat tacaacttat
    22921 gtcctacaga taatttacac atcagaaata ctattttata tcttaatatt attattaata
    22981 tatgtaaaat atagccatct gttaattttt gatacaaaaa aacccacaac tgtgggctat
    23041 ttgcttaggt acatgtattt atttattaat atatctattt tcttacttga ttctactaac
    23101 tcttcttgaa atatttctgg atattctatg tatgtattta tctcttccct aactgcttca
    23161 atctcatttt ttaacgcttc taattcattg ttcgccataa taatcaccac tattacaaat
    23221 ttgtatattt ttatatacat tttatcaaac aatattatat tttgtcaata ttatgtcaat
    23281 aaaacttact ataaaaatgc tttaatttag gtattgtata cctggatact aagcctacaa
    23341 acataccagt tactaatgat gccattaaca taaatggtaa gtaccctata gcaagtatat
    23401 tttctatgat taaacttgca actattaatt gacctatatt atgccctatt gcacctataa
    23461 tgcttatccc tattagtgat aaatctttta ttttactcgc taaatacata aataaaagac
    23521 tcagataagc tcctcctata ctaaatagta gatatgataa agggcctgca aatattgatg
    23581 acaaaattac cctgatagta acaattataa cagtatcttt gacacctaac aacattaatg
    23641 aaattaaagt tataatattg ctcaaaccca attttgcccc tggaaatata actataagag
    23701 gatttggtat atatgtctct agtacatata aagctaaact ataccctatc ataagaccta
    23761 aaaatgtcat ttttctagtt ttcattaagt taactcctcc aaattttatc tatcatctta
    23821 cattataata caaaatatat aaaaacacct aatttagact aaaatatttt taatctattt
    23881 agaataaata ttagttattt caatgtgcaa ttacctctat aaatcttgac tttttgtatc
    23941 atacttgtta caattttaat gataatgaat ttcattagga ggtgttaata atgactgttt
    24001 acgatttaaa aataggagaa aaaggattta ttaatagtat agatggagat attaaattat
    24061 ctaaaagatt gcttgcactt ggatgtataa atagtactga aatagaagtt aaaaaggttg
    24121 ccccacttgg agacccaatt ataattagat ttagaggctt tgaccttgcg attagaaaat
    24181 ctgatgctaa aaatatttct ttacaataat agaggaggag ctacccgtga ttaatgtagc
    24241 attattagga aacccaaatg tcggtaaaac tactgttttt aatctactta caggttcaaa
    24301 tcaatatgta ggtaactggc ctggtgttac tatagaaaaa aaagaaggat ttcttggaaa
    24361 agagataaag gttgtcgatt tacctggtat atatgcaatg gatactttct caaatgaaga
    24421 aaaggtttct aaatcatatt tagaaaatga agatgttgat gtaatagtaa atgtagttga
    24481 tgcttctaat ttatcaagaa acctttactt aacaactcaa cttatgcaat ttaacaagcc
    24541 tatagttata ttgcttaata tgttagacat tgcagaatct aaaggagtta atatagatgc
    24601 caaaaaatta agtgaagaac ttggagtaat tgttgttcca attatagcaa aaaagaaaaa
    24661 tggtgttgat aggatagaag aagagattaa gggagctacg caaaaagctt ttatatatca
    24721 gaaaaacttt ggaagtgaaa cagaaacata taaaaaatta gaatccattt tatcgagatg
    24781 tacaaaaact acatatacac aaaagaaatc tatcagtgat aagatagaca atatagtctt
    24841 gaatcctata ttagcatatc cgatatttat tggtgtattg ttcctcttat ttaaatttac
    24901 ctttgactgg gtcggaggac cactacaaga gggatttgct agtcttatag aggcttatat
    24961 ttctgcacct gttagtgata tgttatctaa ctctagccca tggtttaaat cacttatagt
    25021 tgatggaata attggaggtg ttggtggtac tttaccattc ttccctttaa tatttacatt
    25081 attctttggt atatcgttgt ttgaagatag tggatacatg tcaagaacag catttttaat
    25141 ggataaagtt atgagaaagg ttggtctatc tggtaaagct tttataccta tagttatggg
    25201 tatgggatgt tcttctccag ctataatggc aactagaaca ttggaaagcg aaaaagatag
    25261 aagagttaca gctcttattg caccacttat gacttgtgga gcaaagctac ctatatatgc
    25321 actatttgta gctatattct ttccacataa tgctgcttta gtaactacgt cactgtattt
    25381 ggtgggtata gttatggcaa ttgtagttgc attattctta aataaaacag cctttaaaac
    25441 agaggctgaa ccatttatat tagaattacc agaatataga atccctacta tagatgcact
    25501 tattaaaaat acttggaata aatcaaaagg tttcttgata agagttgtta ctgtcatgtt
    25561 tgcaatgtca gtcgtaattt ggggactttc ttcattcaat gtttttggat atacagaaga
    25621 tataaatgta agcttcttgg ctactctagg tcatattata tctcctatat tcaaacctct
    25681 tggttttgat gattggagaa cttcagttgc tattttaagt ggtcttggag caaaagaaat
    25741 cgtagtaaac tctttaaata tactatatgg taatctaact gttgtcttac caacaatatt
    25801 taatggagtt actgcatata cattcttgat atttactgct ttatatactc catgtatagc
    25861 tgcacttgca actatgaaaa aagaatatgg caataaaatg atgtttacat catttgcata
    25921 tcaatttata ctagcatgga taatggcttt tatagttaaa agcataggtg gagtactatt
    25981 tatgggtaat tcaataatgg aagctttgat aggtggaata attatagtcc ttgcactctt
    26041 tattctgttt aataaattca agtctacaaa aaacggaaat gtctgtagtg gatgttctat
    26101 ttgctctgga tgtccaagtg ctaattcttg ctcaagtaag gaagacagca ataaaaaaag
    26161 taatacacac taatatataa atattttagt ttaaaataag ataaaagtgg gtgtctcaaa
    26221 attaactttt tagttcatga ggcactcttt tttatataaa atcaaatata ttttcatcat
    26281 ttcaacagtc aaaaagaggc ttatctctat tttgagacaa cctctttttt tgttacttat
    26341 tcagtttctt gctacctaac ttcatgtgga acctagtatc ttttggaaca cttgggtcta
    26401 cgcctcttaa tgtaggtatt tccccacata ttagttgtat aggtactata aaattaaatg
    26461 tttgatagta aggattatct gtgatatcaa tctttaaatt tttatcattt tctgtaacat
    26521 ctctacctat agcaaataca ttttccgtcc aaccagaaag tacatcaatc atcttagtta
    26581 ctctaggttc ttttcctgta tctagtataa atatagtaga atcactattt atagcattat
    26641 atataccgtg tataaactct tcaaactcat acccagttac aggtattctc attgtttcca
    26701 ataattttaa tgctgcttct aatgtatctc catatatatc agagtgacct attattctta
    26761 tttctttaga attaactaac ttttctttgt ttctttcaat ccattgttta gagagcttat
    26821 acactgcttc aaatctatta attgcatcta atatcttatt tatttcctca ttgtactttt
    26881 cactagatat tgtacctttt tctctagcta tttgaagacc taataacatt aagtttaact
    26941 ttgtacaata atatcctttt gttttagctc cagatttttc ttcaccacaa tttactgtta
    27001 atatataatc agaaatctca tctattaaag cattcttaca acctgccata gatgctattt
    27061 tacaaccctt atcttcagct aacttcatag cgttgtatgt agaataacta ctcccacctt
    27121 gagatacacc tactactagg gtattttcat tatcaaactt gaatgtatct tcagttatca
    27181 taaatggata cattttcaca acatctatat ctaataaatt ttgtaaatat ggttgcactt
    27241 gcactcctga gtgatagcta gtacctgaac ctgttattat aatctttttt agatttgctc
    27301 tcttaacttc attaaataag ctatctgcat tagatataat ttctctcatt ctaactggtg
    27361 tttctaacat ataatcttgt attgtcattt tatacacctt ccttatctat atattcaata
    27421 aattataatt aatttctata acaaacctat agcatgtaaa gcgattcctg ttactatagt
    27481 gcctatagtt aattttgtta cacttacctt tctcttcaac atgtaatata ttaaaaatgc
    27541 aaaggttaaa ggtaacatat taggtattat tttatctagt atatcttgta aaattacttc
    27601 tgcaccattt aagttaaatt tcaaaggagt agttatactc aacatagttg caaccattcc
    27661 tcctacaacg aataaaccga cagttgtagc catagacatt atcttctcca taagtccctc
    27721 tctttgtatt ctttcaagag aatttacccc tactttataa ccatacttaa gtccaaatat
    27781 tctaagggca aatgctggta tattgtataa taataagaat aatagtggtc caaagatatt
    27841 gccttctttt gcaagtgata ctcctactcc tgctgctata atcctaaatg ttccccagaa
    27901 taatgaatca ccaattcctg caagaggtcc cataagagct gttttaacag cactaattga
    27961 actttcatca aattctggat tattagcatt ttcttcttcc atagctgctg ttatacctaa
    28021 tatagcagga actaccactg tcgttgtatt aaaaatctct aaatgccttt ctattgcttt
    28081 tgcttgattt tctttcttat tatatagctt ctttattgca ggtaacattg aataacaata
    28141 acctaagttt tgcattcttt cgtaattaaa tgcaccttga agagcaaatg aacgccaaaa
    28201 catacttctt aattcttttt ttgttaattt attcaaagtc aatctctcct tccgttaaag
    28261 tattcattgc taattgagga ttttgattat tttctttgtt attgatataa aagtttagta
    28321 caaatgctac acatactcca aataaagcta tagcagttat atctaatcca ccataagatg
    28381 ctaacaaaaa ccctataaag aaaaatacag acatcttttt tgaaatcaac atatccataa
    28441 gcaacgcaaa acctactgct ggcaacaatg ttcctgcaac acccaatccg tctaatataa
    28501 ctttaggtat tgcatttatc aatgttgtaa ctttatcagc accaatcata attgctaaaa
    28561 aggttggaac tgatgtactt aaaaagaata atattactgg caaccacatc attatggtaa
    28621 ctttcttaaa atcagcctgt ttagcataga aaactgcctt ttgagaaaag tacgaattta
    28681 ttattctaac taatactcca agagattgtg ctaatactgc tactggcact gccactgcta
    28741 aagcaacttc tgcaccatta cctgataata tagcaaaagc tgtacccaat acacctcctg
    28801 ttactacgtc tggaggagta gctgcaccta tccctgcaat tcccatccaa attaattcaa
    28861 gctgtgcacc aatcataatt cctgatttta tgtctcctaa aactaatcca actaacatac
    28921 ctgtaactat tggcctatca aacatagatt gaccaaatat acgcccatct agtataccaa
    28981 ctcctgctat aatagctaac atagtagctt gtactaacat attgaacctc cattttaact
    29041 tagtttaatt tacattaaat tacattacat ttttgatttt atttcgattt tctaataact
    29101 catttacata aacaattcca ttttttgctt cctctaagcc tgatttaact attagttttg
    29161 tatcctcctc aactaataag aatatagata aaagcattgg taaatttacg cctgtcaaca
    29221 attcaaattt gaacccttgc aaaagtaagt ttgtacatat atttgccaca cttccaccaa
    29281 acacatctgt taaaacaaca aattcttcac tatctttatt atttgataat atacttctaa
    29341 tttctttctc agcatcatct gctgatttat cttttgtcat acaaaaatac tcaatattag
    29401 ctaatgaacc aattattaat ttacttgtgt caacaagttc tctagacaat tctccatgtg
    29461 ttgcaattag aaattttttc attctctttc tcctaaatta ttttattaaa tctgatagtt
    29521 gtttcttttt gtctctaggt aacattctaa gttctatatc aattcctaaa tcacctattt
    29581 ctttaaagtt atttatatca tcatcatcaa cagcaactaa atctgtaagt ttcttttttc
    29641 cttcttcata tcttaaccct cctacattta tttcttttaa tactcctcct gaatttttag
    29701 ctacaactaa agcatctctg gtatttttta ctaacactaa tacattgctt ttctttgaag
    29761 aagcaaattt ttctactatt tctccagatt cctctacccc ccttatatat aaagttacat
    29821 tgctaggttt cgctaaattc agtgacatag ctttcatttg gtcatttttt gcttcatcat
    29881 ttgcaactag tattacattt atacctagtg atgttgccca tccatatgca acctgaccat
    29941 gtatcaatct gtcatcaatt ctcatcaaag ataccatttt ccccaaatcc tccatcatac
    30001 attaaaattt ttattgttta tactctcatt tatctataaa agcaaaaagt atgccaaata
    30061 ctggcatact attttaaatt tcatttactt attttgtaat cttgtatttt actgtggtag
    30121 accatagata atattataaa tatatcctat ctctgaaatt ggtatttgca cactataact
    30181 cttttctagc acactaaatg cattttttat tagttttact tcactatgat ggtttttgat
    30241 taacaaatcc atatcagtat actcttcaat ttcagtttgt ctaactaatc tttcaatcat
    30301 acaacttaaa tgaacatata aagaaatctt tttatcattt ggaagttttt tcttttgaat
    30361 attttctata gcattgattc cttcttctat tctctctatt atcttttttg aatctaaaat
    30421 agttagactg tctattactc taattaatga aaaattcttt acaatagaat catttatgtt
    30481 ctttattttt tcattttcta ctactctact aaatattcta aaaacatcat cttctccttt
    30541 tcctgatatt atatcctcta acaatataaa atccacccca ttcacatttg gattagcagt
    30601 tcctactata gccatcacat catacatttc aaaaactggt tctttatctc ccatagaaac
    30661 aagactatca taatcataag gtattatttt gacatcaact atcccaatta aactttcgga
    30721 aagtagatgt tggattttta tagcagtacc tatccctgta aaacaagatg atattatagc
    30781 atattcttta tttttttgag gataatacaa ttgtatatta ggtttagttt cttcatccat
    30841 aatttctgca atctgttcaa tgtttttacc ttgcattaat aaatttccta cttctagtgc
    30901 agaaatagtg gatatttggt ctataaataa cattggccca tttatcttat tttttaaatc
    30961 ttcatagata agattaagag agcccatatc aaataacaca attaaaccat tctttatcct
    31021 atctccttct aggtatctag acatttgttt tgatacatca gcaatggtag catctatagg
    31081 catatcaata gctgtaaata tatttttacc caacatccga ttacatacat tcgccatact
    31141 actggcagta gcatatccat gtgctataat agtcgcatta acttgattaa atttcattct
    31201 tataattgtt gatttaataa atataatcat tatgattgta tctacattat taagatacat
    31261 atccaatcta ttcgttatta atgttgatat tttacttatt atagagtatt ctttgtaact
    31321 ctcttttttt aaatatatta gtaatttact ttctaaagct ttatactcat cagataattg
    31381 ataagattcg tccttcaaat aaagataaga cgaaaatgcc aatacattat tcccatcgta
    31441 ttttatattg ttattaactt ctaaatttct aaatatatcc tgcattatcg atattataag
    31501 ctccataagt acgttattat tttcatcatt atttgaaaag actaaattgt ccattagtct
    31561 aatcattaga ttagaactct ttttactaaa tatttctttt gttatttcat ttttttctag
    31621 tctatcaaag tagtctaaac attttatgaa actttgatag attatatttc ttttatttct
    31681 tccatttgac atttcaatac taaattgttt aggagaaaag ataatgcttt tgcttttacc
    31741 actttggaat tgaaatatat ctacattttc tatataaaga tttctaggga ggtcttgaag
    31801 agtaacaaaa atatttccat ttcttctttg attttttgca taagctcgtc cacatgcata
    31861 ttttattaca tttttacatt cacctatatt ccccttgaat tttatcttta aaatcgtatt
    31921 taatgtaatt tgagttatct ctataggcaa gccaagtacc ttactttctt cataaataaa
    31981 atgttctaca atctttcttt tttcaatagt ccctctttct tctatattgg gaacataaat
    32041 atttatgggt attcttctta aaaaagtttg caaaaatttg gatagacttt ctgttgttgc
    32101 aaatattaat cttaccctag cttttctaat tactccattc tctccaatcc tagaaaacgt
    32161 acctgtatcc ataaatgtaa ataacttttc ctgaccttca ctatttaatc tatgtacttc
    32221 atctaaaaat aaaacaccac catctgattg ttctattaga cctgctctag attcatttgc
    32281 tccagtatat gctcctttta catgcccaaa taatagacta gacaataact ccaaattatt
    32341 ataatactgc gcacagttta acacattgta tggagaattt ttttctaata cattactgct
    32401 tacactatat ttgtatatta tcttggctaa aaaagttttt cctactccac tttcacctgt
    32461 cagcattatt gtaagtccgc catttggata aagtacagcg gtttttattt gttcgattac
    32521 ttcttttaag ctattatcat atcctatgat actattaaac acagtctctt gctttaataa
    32581 tttacactca tttttaagtt catctaaatt ttcataaata cttttttttg taggtcctac
    32641 tacatcattt attttatttt taggtaaaaa aataacaggt ctactgttta tctttataag
    32701 attatcagat tttactaaat catttaataa tctacttgat tgagttctac ttaaattaaa
    32761 cttttttact atatcttctg ttattatgcc actttctttt ttaagttcat caaagttgtt
    32821 aaataataca cattcattta caaaacttaa aatttcatcc ctcatgttca acctccaata
    32881 caaatatcaa taatactata atattagtat atcatttata tatttatgaa aaagataatt
    32941 atattcctat cttgattctc ttttgtaagg ttgtaaaatc aaacttttta taagtataaa
    33001 atctagattt tttaacataa tctcaaggtt cttatctttc catatatctg acatagaatt
    33061 tatataagaa tatatttatt gtatttatta taataaaaag taaaacatta taggtatttt
    33121 aaaacttatt agcgaagaaa atatttgtaa cttttattac cttatgaata ttatttcaaa
//
LOCUS       DAMJWO010000045        32613 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.046, whole genome shotgun sequence.
ACCESSION   DAMJWO010000045 DAMJWO010000000
VERSION     DAMJWO010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32613
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.046"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(135..974)
                     /locus_tag="PC366_002144"
     CDS             complement(135..974)
                     /locus_tag="PC366_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2577671.1"
                     /translation="MSDIKNEVSKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKEELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMFILIVVGAITGIL
                     GLF"
     gene            complement(998..1756)
                     /locus_tag="PC366_002145"
     CDS             complement(998..1756)
                     /locus_tag="PC366_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2577672.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNENVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(1803..2276)
                     /locus_tag="PC366_002146"
     CDS             complement(1803..2276)
                     /locus_tag="PC366_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2577673.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITSAKRIVIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSHNGDEHLIVLVKYPKTVLGLVNSGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELISKDVKCFIQIVPDAKKIDVGTLL"
     gene            complement(2305..2721)
                     /locus_tag="PC366_002147"
     CDS             complement(2305..2721)
                     /locus_tag="PC366_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2577674.1"
                     /translation="MIHMTGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRRLEDRIEKYKDEGVLVLLDFYGGTPFNTSAIIINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLKL"
     gene            complement(2768..3820)
                     /locus_tag="PC366_002148"
     CDS             complement(2768..3820)
                     /locus_tag="PC366_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF2577675.1"
                     /translation="MKSVRFYGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGTIGLFSIQWAKIFGSTKIIAVDVFDEKLDLAKELGADICINAKEKNI
                     VEEIKRLTDGDGADIVIESAGTPMTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEK
                     IVRSELTVKGTWFGNSFPFPGKEWSAGLYHMQKGDMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIDN"
     gene            4216..4896
                     /locus_tag="PC366_002149"
     CDS             4216..4896
                     /locus_tag="PC366_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDF2577676.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSVKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(5029..5349)
                     /gene="sugE"
                     /locus_tag="PC366_002150"
     CDS             complement(5029..5349)
                     /gene="sugE"
                     /locus_tag="PC366_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000118520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HDF2577677.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     gene            5731..6558
                     /locus_tag="PC366_002151"
     CDS             5731..6558
                     /locus_tag="PC366_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HDF2577678.1"
                     /translation="MNFYKIAVCQMMTTENKIENINHAVDMVTEAAINGAKIIVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEYGKIYNTCYVFDK
                     NGALIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGIAICYDIRFPE
                     LSRLMALKGVEIVILPAAFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGRIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
     gene            7379..8053
                     /locus_tag="PC366_002152"
     CDS             7379..8053
                     /locus_tag="PC366_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2577679.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNGYEVYTAQSGKDSLKKISK
                     NPDIILLDINMPEIDGIEVCNRIRDYVSCPILFLTARIENTDKINGFRAGADDYIVKP
                     FDLDELGARVSAHLRREQRKSNQTKIKFYNDLTIDYEKRLICIYNNQISLSKKEFDIV
                     ELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKHTLENYIETVWGV
                     GYKWIK"
     gene            8041..9201
                     /locus_tag="PC366_002153"
     CDS             8041..9201
                     /locus_tag="PC366_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2577680.1"
                     /translation="MDKISNMSLKKAFFVLTLSSLIIASVLTTFAYILLNNLYNSIQD
                     KYLKTPINTGIITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNINMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIENLDENISIIAKQEGKSFTLKSQINNINLF
                     FDENIILRVVENIISNAFRYARNNVSILIYLEQELLTFVIEDDGIGFSKESLKLALRP
                     FYRDKTLNDSNPHFGMGLHISKILCEKHGGSISIENNSTNSAKITAKFSTRN"
     gene            9418..9945
                     /locus_tag="PC366_002154"
     CDS             9418..9945
                     /locus_tag="PC366_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014118918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HDF2577681.1"
                     /translation="MKSFANNITFSRIVFALLMLSSTFCSLPFWICYFWCGISDILDG
                     LIARKLRQQSGIGAKLDSIADFIFAVTILVTVGKNIALPMYLWWCIVAIALLRLISYS
                     IGFFKYRTFSSLHTLMNKITGISIFAFPLLYICFGLDVAGIMICIVAFLSSFEEIAIM
                     IKSKELNRDIKSIFM"
     gene            10231..10899
                     /locus_tag="PC366_002155"
     CDS             10231..10899
                     /locus_tag="PC366_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577682.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLKINSGEFVSVIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHTEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKDYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            10902..13370
                     /locus_tag="PC366_002156"
     CDS             10902..13370
                     /locus_tag="PC366_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577683.1"
                     /translation="MKNYLSLSIKELKSQKLMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIKKDDRVYQAGTSITIGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGHLPKDKNEIALDENTLKLMGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGTSENLLPKRYILSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRAIGAEPNQIYKIVILQILILCTVAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYMFPLVLSTNVSLI
                     FSFISALPSAIYASRVSPKIAMAGSTTKIKRKIKREKAIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNVLDVSRSVSNLKEGDFSLTNEISGFDKSTLDKIDKM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITDSILEDFK
                     NGSICFIKNPIAISTPGVKTRHTNLKPKDSITINKKQLDIYSTVDKMFFLQGNGWING
                     VDVIVYNSVYNTLTNKNKFNQINIYAKDKSKLEQIRLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIEFLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNISLY
                     KMFLWEGVYYGIFAAIFGSIAGYASAIIINMATIEKLDFTNIPITSILQATIISVLAC
                     IIATLIPLRKVKKMNIIDCIDINL"
     gene            complement(13610..15034)
                     /locus_tag="PC366_002157"
     CDS             complement(13610..15034)
                     /locus_tag="PC366_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2577684.1"
                     /translation="MKNQSLITQFRHTFIFIIIASIVATVITYVFALYLYIHSLNKDI
                     YPPNYYERQVPRIEKYINEKNITLLSQSNEEGLKRTIRGDDMPYQVVDNNGNILYGTN
                     PKKLFKTKEELFNNFINKTVRKGGYIHTVPIKGDNGKIEGAVILFYQVKITFANSRGR
                     FVFAVIIMALFSPFIYIVGFTRWLSKRFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKGSLSAQWKMEQERVEMVEALAHDLKSPLSIILGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNLVPINLPEFLRQ
                     KVQDYELQAHQKEVELILKMKGNIQSPIQIDVDRLTRIFDNIISNSLQYTPSGGNISI
                     TVKDEKNCISYEICDSGRGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(15053..15745)
                     /locus_tag="PC366_002158"
     CDS             complement(15053..15745)
                     /locus_tag="PC366_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2577685.1"
                     /translation="MSKILIIDDEMDLVMLLEDELKAKGHEVLIAYDGQAGIELSKQE
                     PDLIILDIMMPKMNGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFGKLCLYMKERAIKIDGKNIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            complement(15800..16576)
                     /locus_tag="PC366_002159"
     CDS             complement(15800..16576)
                     /locus_tag="PC366_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HDF2577686.1"
                     /translation="MIKLLSSEWLRAKRTAVQWLTLCMPIIFSLCVVFYLTTKSGSTQ
                     EFAFEGFFTVWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMSIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGEKVWAFVPWTWPVKLGMLPGIYFIKEAGTISTEA
                     FYSKVMQTASIELIVVAIGLIIFLIGGVIWFKMWEGRKSY"
     gene            complement(16573..17343)
                     /locus_tag="PC366_002160"
     CDS             complement(16573..17343)
                     /locus_tag="PC366_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HDF2577687.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QTTSWAWQSLLALIFNWWSFLFLPIGFALFATLVAFQEKKAGNYRALRTHNVSPMTLW
                     INKVIAMAVYSFISTLVLIVVTIITGLILKAGPVPFGQIIGASIVCWVVSLAILPLQL
                     WLATWKGMFLSMGVGALGMIFGVLAATKPFWIAVPWSWAVRMVCPIINIHPNGTILEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            complement(17340..18044)
                     /locus_tag="PC366_002161"
     CDS             complement(17340..18044)
                     /locus_tag="PC366_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF2577688.1"
                     /translation="MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTDGRIIFDRKPWKRESLAKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
                     DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            complement(18299..18811)
                     /locus_tag="PC366_002162"
     CDS             complement(18299..18811)
                     /locus_tag="PC366_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577689.1"
                     /translation="MKKISQEKISTHIQEVPQEKIEQWKSLYEKYKSILKVNSKSVLE
                     IIEFLKRKYVIVEETSEEFKHVVINNIKLNKPFSQKISSDKELKPIVFTIPNEGNAKK
                     LYDTQEETYSGCKIIVGMEFETGCVFVEGSDELNDEITSFKGLDKYDISNYYLVANYI
                     RCLKKYKLID"
     gene            19137..19394
                     /locus_tag="PC366_002163"
     CDS             19137..19394
                     /locus_tag="PC366_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577690.1"
                     /translation="MILNRTELFRGYSLNRFNEICNILSVNKIKYKYKVKNNAYSKKP
                     FSNEITLGNLGQKEDFSYEYLIYVHKDDYEQAESLINSKLR"
     gene            19537..20163
                     /locus_tag="PC366_002164"
     CDS             19537..20163
                     /locus_tag="PC366_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HDF2577691.1"
                     /translation="MKINIKSKLSEFIKQNNLFDDNRIISYLPNITIETDKIKTIMIN
                     EVVPTNTNDDFYSVDKDADYLKTTIPLFDSAGIEVSNINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            complement(20413..21192)
                     /locus_tag="PC366_002165"
     CDS             complement(20413..21192)
                     /locus_tag="PC366_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901940.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HDF2577692.1"
                     /translation="MNSKIYYFSGTGNSLVVSKILKETLNGSKEVIPLAIHRKENNID
                     INEDILVIVFPVYFADVPDIIKSFVEKLNFNINTHIYAIATCNGVAGHSLFTIDKLLK
                     KRGKKLSAGFLINMPGNALITPSDVEEERLKNQTNRVAEIAKCINNLEIGNIEGKNNL
                     KSHIDSVVLRLVGKNMQIATTKFFAENKCNGCGTCKRVCPVENISIVDKKPKWGNECE
                     RCLACFHWCPKEAINVKKSFLTNRKKYHHPDITVKDIFLDK"
     gene            complement(21260..21721)
                     /locus_tag="PC366_002166"
     CDS             complement(21260..21721)
                     /locus_tag="PC366_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2577693.1"
                     /translation="MGGAGDYLNGGKMKDFEKLYEATTKLVSTSLKVKDDLKKMFKQN
                     GYDITTDHYALLRFLWEQDGISQIDLCEKSCKDKSNTTRILDVMKNKGLIVRKVDVKD
                     RRKFQIFLTDLGRELEEPLNEIASIYATETFKSISDEELPLFTDILDRIGK"
     gene            complement(21697..22374)
                     /locus_tag="PC366_002167"
     CDS             complement(21697..22374)
                     /locus_tag="PC366_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2577694.1"
                     /translation="MIITVINGSPRKNGATSKVLTYLYKDIERLIPDVKINYFDLSEV
                     NPSYCIGCLNCYKMGKCINQNDKVEYIHDIITKSDGVIFGSPTYGSSVTGLFKVFTDR
                     AHMMLERLLYRKPCIAVTTYENARGSKAISFIKSMVLDSGGYVCGSLSIKTGFNQNPI
                     TEKVESKIQKVSKKFIYCIEEKKNPPVLSQIYNFIAINAVLKPMAFKDIEQYKGIIDR
                     WEEQGII"
     gene            22607..22993
                     /locus_tag="PC366_002168"
     CDS             22607..22993
                     /locus_tag="PC366_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2577695.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVATESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            22996..24795
                     /locus_tag="PC366_002169"
     CDS             22996..24795
                     /locus_tag="PC366_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HDF2577696.1"
                     /translation="MYAPFFIRFLLSTLTLSILIVIILLAKKVFKKHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSSTNRTSIIKNSPNSIINNSNALNDF
                     SVSLNQVNFDSLNILLLISWIIGILIMIAITIHCNIKIKNMKKSIQILRDEEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNKDILINYIMCFLQILYWFNPLVWYAFKEMRIDREIACDISVLKKLDKDSHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNEQTVYEDLSQYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRNNSHIPWDGKHHSNSSWNEDQDLFSAMENS
                     VNWYFQTLDKKTGLKNIQTYLKQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFKFEDKNIETVKDSLLISKKDGVSLFGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNGSSASKITLSILNDKKIYNP"
     gene            complement(25150..27024)
                     /locus_tag="PC366_002170"
     CDS             complement(25150..27024)
                     /locus_tag="PC366_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2577697.1"
                     /translation="MNKYNKIANELIEIIGENNIISITHCATRLRVMVKDREIINDKK
                     VEKVNEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEVEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIGLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVFSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDIA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
     gene            complement(27029..28693)
                     /locus_tag="PC366_002171"
     CDS             complement(27029..28693)
                     /locus_tag="PC366_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDF2577698.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDATPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSKYSDCLIYGSIEPIDIESDNVIAYRRQLDLVVIDCY
                     YNFSDKLVEIKTEEKYDIVFQNLDDINLLNKTVSLKPFQAVLLKVR"
     gene            complement(28707..29528)
                     /locus_tag="PC366_002172"
     CDS             complement(28707..29528)
                     /locus_tag="PC366_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2577699.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSIGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDVHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            complement(29627..30391)
                     /locus_tag="PC366_002173"
     CDS             complement(29627..30391)
                     /locus_tag="PC366_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2577700.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVVKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDTSTIIDFAKEMRMKGTYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            complement(30388..31137)
                     /locus_tag="PC366_002174"
     CDS             complement(30388..31137)
                     /locus_tag="PC366_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2577701.1"
                     /translation="MRLESLVNQSYNSLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KSDLFIIISLSGETKSGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            complement(31641..32246)
                     /locus_tag="PC366_002175"
     CDS             complement(31641..32246)
                     /locus_tag="PC366_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2577702.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMKIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMMKSIRELDNLKYEWICMSHGTPCIK"
     gene            32425..32523
                     /locus_tag="PC366_002176"
     CDS             32425..32523
                     /locus_tag="PC366_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HDF2577703.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFD"
BASE COUNT        11549 a         5401 c         3940 g        11723 t
ORIGIN      
        1 ttatataagt ttaaaattta atctattata aaattaccct aattgctaaa ctttttaata
       61 taaattttcc aacatcttac aaatataatc aatagatata gaatcctaat ttacacacca
      121 acatatatat ttatttaaaa tagtcccaaa atacctgtaa tagctcccac tactatcagt
      181 ataaacatta tttttattgg agaaaggcct ttttttaaag caaagagtac taataaagta
      241 agtaccaaag gaattaatcc tggaaatatc ttatcaagta aatccgtttg aagactaaat
      301 ttaaaatcac cactagtata acttattggt gtagataaat taataaacct acctacaagt
      361 ccccccatga ctaaagtacc taatatagaa gccccttcta taaccttatt tactattcca
      421 ccttgaagta tactttcaac agcttttttc ccatacttat atccatttgt ccacattcca
      481 aaagaaattg aagtcattat tatatattga gctattacaa ataatatagg acctgcaatt
      541 gatgctcctc cctcagttaa accaatacaa acagctaaca ctataggagt tataactcct
      601 tgagttaaag tatcaccaat tcctgctagt ggacccatca agcctgtttt gatagcattc
      661 ataccatctc cacttatttc atctgctcca ttagcttttt cttcttccat agctattgtt
      721 attccatgta taacacatcc acatataggt tctgtgttaa aaaatgctaa atgagtctcc
      781 acttcttgtt ttaactcttc cttatctgga tataattttt taagtactgg caacattgaa
      841 tgtgagaaag ctgttgattg caatctttca taattgtaat tagattgcgc aaagaaaaac
      901 catcttaacc atgattttat tacatctttt ttgcttaacg ttttcttaga tacttcattt
      961 tttatatctg acataatatt ttccccctca catgtattta agatgtagca ctatcttttc
     1021 cgtacttaat tgaagtaatt gtaagagcaa gtattactcc aataacagat attactatta
     1081 tatctacttt aaaataaaca gccattagta ttcctaatat gaaaaagggc atagtaaact
     1141 tgtttccaat caattttaaa ttcatagcaa tcccaagtgc tggcaacata gccccaatta
     1201 cattaaatac atgtaacaca ttctcattca ttacttccaa cataccatct atcgcatttg
     1261 gaccaaaata aacaactaat aatgctggta taaaactcat tgcaaataac agtatctgtg
     1321 gtggtactat atttataaat gctactctat caacattccc tttttgaacc tctctatcag
     1381 cccaatgtgc aaaaaaagaa tttactgtca tttttccaat ccaaagtaca gttgcaacag
     1441 ttcccaatgg tacagctatt gccattgcag tacttacatc tagcttagat gctatagcta
     1501 aagcagtacc tacatatcct gcaaaagctg ggtcccccat ctgagctccc cctgctgata
     1561 taaaacctag atatatcata tttatacctg ctcctataat tgctccttga acagggtctc
     1621 ctaatataat tcccgttaca aatccagcca atagaggtct attccatgta aaaaatccaa
     1681 cataggtcaa ccacggactc caagaaagat aataaaaaat tgctattaat actgcttgaa
     1741 ttagtgaaat gtgcatattc ttcctcccta ttttctttta aagatttaca agatagtctt
     1801 ttttataata atgttcctac atcaattttc tttgcatctg gtactatttg tataaagcat
     1861 ttaacatctt ttgatattag ttctctaaat atttcttttt cttcatctga cacagatata
     1921 tttttataaa aactttttct accaagccct gctcccatac ctccaacatt caattccttt
     1981 aaatctaccc cactatttac taaacctaag acagttttag ggtatttgac caatactatt
     2041 aaatgttcat ctccattatg tgattttaaa acttcagcac ctgattctac atcatgtact
     2101 tcaaccttaa cagttgatgg agctgccatt tgtaaaactt gaactataaa tgggtccttt
     2161 actactaaat catccacgat tactatcctt tttgccgatg taatcttaca ccaagcagta
     2221 ataacttgcc catgtattaa tctatcatca attcttgtta atgctatatt actcataatt
     2281 attcctccag atttttaatt tattttacaa ctttaaaaca gttttaacat ctttgattcc
     2341 tgatatccca acttcctcac ataaattctt caagtctttt aacttcatag tatctctgtt
     2401 taaaaatagc tctaaaagca taggtaaatt tacacctgtc aaacattcta actcacatac
     2461 cttagcaaat ttatttatta taatagcaga tgtattaaat ggagtcccgc cataaaaatc
     2521 aagcaatact aaaacccctt catccttata tttctcaatt ctatcttcta accttctact
     2581 aaactcatct atgctgtcac catggtttaa tcctaaagtt tctacatttt cctgtttgcc
     2641 tactattaat tcagcacttt ctaacattgc tttagccata tttccatgtg tggctataat
     2701 tatccctgtc atatgaatca tacctttctt aaccttgttt atatggatta ttatttagta
     2761 ctctaatcta attatctata ttaatcatta tcttaccaaa gaaaatatcc cttttgtata
     2821 ctttttcaaa ataagctggt acttcttcta aatttattct atgtgttact aatttttcaa
     2881 cattcatatc acccttttgc atatgataca atccagcact ccattctttt cctgggaatg
     2941 gaaaagagtt tccaaaccaa gttcccttga cagttaattc acttcttact atcttttcaa
     3001 attgttctct agtcaaagct acatccccat atggtacacc tgcatacaat actgtccctc
     3061 cctttttagc taacaacaat acttgcccac atgtcattgg agtcccagcc gattcaataa
     3121 caatatctgc accatctcca tcagttaacc tttttatttc ttctacaata ttcttttctt
     3181 ttgcatttat acaaatatct gcccctaact ctttcgccaa gtctaacttc tcatcaaata
     3241 catctacagc tattattttt gtagagccaa atatctttgc ccattgtatt gaaaataatc
     3301 ctattgtacc tgtaccaagt actacaacag tatctccaac tttagcttct gatctaaaaa
     3361 gaccatgccc tgctatacat actggttcta gcgcagcggc agtctcataa cttatctcat
     3421 ctggtatttt tattaaattc ctctctttca cctttgtata ctctgcaaaa caacctccaa
     3481 gttctttatt tcctattatt gctacattat tacatcttga atacaatcct tttttacatt
     3541 catcacattc aaaacatggc atagctggac aaacagcaac tctatctcct attttaaaac
     3601 tccttacttc tttaccaacc tgtgccactt ctccagaaaa ttcatgccct aaaatttctc
     3661 caaccatatg tggacctgtc tttgaatatt ttgatatatc agaaccacat attccagcta
     3721 cttttacttt aattattaca tcatcttttt ctaatatttt tggtacatcc acatcctcca
     3781 ctcttgtgtc tcttatacca tagaatctaa ctgacttcac tattaaccac ccctactttt
     3841 tatttgagaa tatatcccta ttgtttatat gttaaatatc taaagcaact ttcatgccaa
     3901 tatatgtaag cattgcattc atgcatttta taaaattatc attaaatgtg tgtcaaagtg
     3961 tgtcaaaagt ttcttatatt aaaacttatg tgtgtcaata taaacgacac taacatttta
     4021 tattagttct cttattataa gttttataaa atgtactttt tttgttattt ttataaaatt
     4081 gttcggaaat ttcccttcta tttgtgatat aatattaaat ataaggtatc aatataaatt
     4141 ttcatgcgaa tatcagaact tttttgacac taatgcctta ttcaatataa taatttaact
     4201 ttttggaggt tgtttatgaa aaaagtgtat caaggaaaga ctaaagatgt ttttgaatta
     4261 gataatggaa attacttact taaatttaaa gacgatgtaa ctggtaaaga tggagtattt
     4321 gacccaggcg aaaatagtgt aggtctaagt atagatggaa ttggtagagc taatttagag
     4381 acatctgtta agttctttga aattctaaac aatgctggaa ttaaaactca ttatgtaagt
     4441 gctaatttag aagaagcaac tatggaagtt ctaccagcaa aagtttttgg taatggatta
     4501 gaagttattt gtcgttatag agctgttggt agtttcttac gtcgttatgg ttcatgtgtt
     4561 gaagaaggtg ctaaactaga ttgctatgta gaagcaactt taaaagatga tgaccgttgt
     4621 gaccctctta taacatctga aggtttagaa gctttaaaca ttatgactca agctcaattt
     4681 gattcaatga aaagcatgac tcaaaaaatt tctaatatag ttcgtgatac tatagctgaa
     4741 aaaggtcttg aactttatga tatcaaattt gaatttggat tctacaatga tgaagtaatc
     4801 ttaatagatg aaatagcatc tggaaatatg cgtgtttata aagatggtgt aatagttgac
     4861 cctatggatt taactgctct tttattagat aaatagtata tacatataat tttcaaatat
     4921 aataaactta taaataagat aagctatgaa gtaaagactt tttaaatgtt gattattttt
     4981 aaacattttc tcgcctttaa tttcatagct tatttaaatt aatatactct aattagtaga
     5041 taatagcttt aaccctacaa ttcccaccac aataaagcct atacatgcaa ttcttgatat
     5101 actaataggc tcatttaaga tagccatgcc tacaatagct gtaccgacgg taccaattcc
     5161 agtccatatt gcatatgaag ttccaagtgg aagatgtttt agtgctaatg acaaaaaata
     5221 aaaacttaca atcattccaa caacagtaag tatacttgga gttaatttag aaaatccatg
     5281 tgaatttttt agttgaaaag cccaaaacac ttcaaacaaa cctgcaacaa acaaaaataa
     5341 ccatttcata aactcatccc tcttttcaaa tgtatctctt atttttccaa taaaataacc
     5401 tgagaaatat tataaaatat ctcccaggtt tttgtccttc cgtgttcaca acaaaaacta
     5461 tgttgtgggt tttatctcgg accaggccaa tcattaataa ttgcaaaacc ctataaaact
     5521 ctattaatta ttctatttta tctataataa tactatcaac atatataaaa aaagtcaata
     5581 tatgggttcc atctataata aaaataactt ttatatacct tttaatattc ttattcactt
     5641 ctctccatac ccatttaggt caatctaaga atatctaatt tttatttaat atgttataat
     5701 aacataaaaa tattgaaagg agtaatttct atgaatttct ataaaattgc agtatgtcag
     5761 atgatgacca cagaaaataa aattgaaaat atcaatcatg ctgtagatat ggtaacagaa
     5821 gctgccatca atggagctaa aattatagtt ttgccagaaa tgtttaactg cccatatgaa
     5881 aataaatatt ttcctaaatt tgctgaagaa tatccaggtg aaacaacaac gatattgagt
     5941 aaattagctg agaaacatgg aatttatcta gtttctggta gtattcctga gttagaatat
     6001 ggaaaaatct ataatacttg ctatgtattt gataaaaatg gagctctaat tggaaaacat
     6061 cgtaaaatgc acttatttga cattgaagtt acaggaaaag ttagttttaa agaatcagat
     6121 actcttacag ctggaaatga tgtcactgta atagataccg aatatggaaa agttggtata
     6181 gctatttgct atgatattcg tttccctgag ttatcacgtt taatggctct taaaggtgtt
     6241 gaaatcgtta tcttacctgc tgcatttaat atgactactg gtcccgccca ttgggagtta
     6301 tctataagaa tgcgtgcttt agataatcag atattctatg ttggtgctgc acctgctaga
     6361 aatatgaatg cttcttatat agcttttgga aattcaagaa tttcagaccc ttggggaaga
     6421 ataattgctc aagctgatga aaaagaatgt attatttatg ctgacattga tagagattta
     6481 attcctgaca taagacaaca gttaccactt cttaagcaca gaagaactga tttatatgaa
     6541 cttaatactt tgaaataaaa cagaacataa ccccataaat cataaattaa gtgttaaaaa
     6601 aatttatggg gttctcatta atttgattta aaattaattt aataaaaata atgctaaaat
     6661 taatttaatt aaataatact aataattact aatgattatg ctaattgtca gcatttacta
     6721 atttaatcac tattagttat ttcttttatt aaatatcttt acttttttta cttattatgt
     6781 cttctagctt tacatgtgga ttatggtatt tctttctatt tttagtcaca tctttctatt
     6841 gaattgcttg cttaaaacac caatgcacac atgccagata atgttcacaa ttatgtaaaa
     6901 atattgctct accttcttca atgttgatat tatctctcct agttaatatt atctttccta
     6961 aaatttcttt taattaaaaa acaacattag ttgatatatc aagtatattt taagcaactg
     7021 aaaaaataat aataattgat atatcaacta attaatgtag attaattcat ttttataatt
     7081 tatatacttt ttaattaatc taccttttta attaaaatcc ttcctttcta tttatccatt
     7141 ttcaacttaa attataagat ttcatcagct gtgtttttgc attccaataa atattaaata
     7201 tcaaatatat attctattaa aatttctaat aatttcatcc ttgatttatt taatatataa
     7261 aaatatacta actttaatga ttaagttttg aaatataact aagaatttga gaatttattg
     7321 agatttttat actaaaatat aaatactata caaacttaat ttagaaggga gcattcttat
     7381 gaacaataaa atactcgtcg tagatgatga ggaaggtata ataacactct taaaagatta
     7441 ctttgaaatg aatggttatg aggtttacac tgctcaaagt ggaaaagact cattaaaaaa
     7501 aatatccaaa aatccagata tcattctact tgatataaac atgcctgaaa tagatggaat
     7561 tgaagtttgt aatagaatta gagattatgt atcatgccct attctatttc ttacagccag
     7621 aattgaaaat actgacaaga taaatggttt tcgtgctggt gctgatgatt atattgtaaa
     7681 accttttgat ttagacgaac ttggagctag agtatctgca catttaagac gtgaacaaag
     7741 gaagtcaaat caaactaaaa ttaaatttta taatgattta acaatagatt acgaaaaaag
     7801 gttaatttgt atatataata atcagatttc actttcaaaa aaggaatttg atatagtaga
     7861 gcttctctct atgaatcctg gacaggtatt tgataaagaa aaaatatatg atagagtctg
     7921 gggatacaat agcaatggaa atagtgatgt tataatggaa cacattagaa aaatacgaat
     7981 caaactatca aaacatactc ttgaaaatta tatagaaaca gtctggggag ttggttataa
     8041 atggataaaa taagtaatat gtcattaaaa aaagctttct ttgttcttac tttatcttca
     8101 ctaattatag catcagtact tactactttc gcatacattt tacttaataa tctatataat
     8161 tctatacaag ataagtattt aaaaacacct ataaatacag gtattataac catagttcaa
     8221 aacaatgtga accaatttag tgattatgat aaaacattac ttaatataat caacatactt
     8281 cagcttgtac ttccacttat attttttata ggacttttat tattagctga tataattttt
     8341 tacaaggtaa aattaaaaac acccatagaa atcctcaata aaggtgcaat ggaaatatcc
     8401 aacaacaatt tagatttttg cttagaatat aataataatg atgaattagg taatctatgt
     8461 aatgcttttg aaaaaatgag gtctgaacta aataaaaaca acataaatat gtggactatg
     8521 attaatgata gaaaacaact taatgctgct ttttctcatg atttaagaaa tcccctaaca
     8581 gttctaaaag gttactcaaa ctatttaaca aaatacatac caacaggcaa acttagtgat
     8641 gagaagattt tatcaaccac acaacttatg tctgagcata ttaacagaat tgaatactat
     8701 gtagaaaata tgagtaatgc tcaacgatta gaagatttag ttgtttcaaa atctatgtcg
     8761 aatataaaca agtttataga aaacttagat gaaaatatat ctatcattgc taaacaagaa
     8821 ggaaaatctt ttacacttaa aagtcaaata aataatataa atctattttt tgatgaaaat
     8881 atcattctta gagtcgtcga aaatataata tcgaatgctt ttagatatgc tagaaataat
     8941 gtatccatac ttatatatct tgaacaagaa ctccttacct ttgtaattga agatgatggt
     9001 ataggattta gtaaggaatc tctaaaatta gctttaagac ctttctatag agataagact
     9061 ttaaatgaca gcaatccaca ctttggtatg ggtcttcata tctcaaaaat attatgtgaa
     9121 aaacatggtg gctctatttc tattgaaaat aattctacta acagtgctaa aattactgct
     9181 aaattctcaa caagaaatta aaatgatttt gtaagctttc attgttctta tataagcttt
     9241 gttagtttag aatttataaa atgtatttca atttacaacc aatatatata ctattttgta
     9301 gaagttgtaa gagttgcttc aattataata ttttggcaaa aggcatttga aacaataata
     9361 gaaatatata tttaaatatg tagaatagta tgaaactaga attttggagg tgattatatt
     9421 aaaagttttg ctaataatat tacattctct cgtattgtgt ttgcattgct aatgcttagt
     9481 tctacattct gttcactgcc tttctggata tgttattttt ggtgtggaat tagtgatata
     9541 cttgatggtc ttattgcccg aaagttgaga caacaaagtg gaataggtgc aaagttagat
     9601 agtattgctg atttcatttt tgcggttaca attttggtta ctgtcggaaa aaatattgct
     9661 cttcccatgt atctatggtg gtgtattgtt gcaatagcat tattacggtt gattagttac
     9721 agtattggtt tttttaagta tcgcacattt tcatcgcttc atactttgat gaataaaatc
     9781 actggaattt ctatctttgc ttttccatta ctctatattt gctttggtct tgatgttgca
     9841 ggaattatga tatgtatcgt ggcttttctt tcttcttttg aagaaatagc aattatgata
     9901 aaatcaaaag aattaaatcg tgatataaaa agtatattta tgtgacaact tagaatttgt
     9961 gacaaaaata atttatataa taatgaggaa gtaaaacata aaaaattatc cacaagttta
    10021 tgtgtaaaat agttttaaag caatagagtt gtattgtaaa gcctttagtg cataaattac
    10081 attttaaatt aaaaatgata ctgaaactgc ttatcagcac tgcgaattat ccgtaaatag
    10141 tgaagacttt ttagatttaa gctaaaagtt gggaaaaaat tgagttttaa aacttacact
    10201 cttcttatat agaaaaggag agtgtttttt atgattataa aagcaaaaca attatcaaaa
    10261 atatatggtt ctaataacaa taaagttata gcacttaata atgtaaattt aaaaataaac
    10321 tcaggtgaat ttgtttctgt aattggacct tctggaagtg gaaaaagcac acttttacat
    10381 attttaagtg gattagataa tcctacctct ggacaagtgt tacttgatga taaagatata
    10441 tataaacaca ctgaaaaaga actatctgca cttagaagaa aatcctttgg attcgtcttt
    10501 caacaattta atcttttacc tgttcttaca gcatctgaaa atatttcaat gcctgtactt
    10561 ctagataaaa aacaacctga taaagactat ttaaatgaaa tttcatcatt acttggaatt
    10621 gcagatagac tcaatcatct tccccatgaa ctttcaggcg gtcagcaaca aagagttgca
    10681 atcgctagag cacttattgc aaaaccagat ataatatttg ctgatgagcc tacaggaaac
    10741 ttggacagta aaagtggcag tgaagttatg aatcttctta taaaaacttc aaaacagttt
    10801 ggaaagactt tagtggtaat tactcatgat gatagaattg caaaacttgc tgatagaaaa
    10861 atttcaatta ttgatggtgt tcttatggag gtgaaataga aatgaagaat tacctttcac
    10921 tttcaataaa agaattaaaa agccagaaac ttatgactac attcatcatt atagcaatag
    10981 tactatcaac tattatgaca actgtggttg gacagtcaat tggtatccta caaaatttaa
    11041 gaattgaaca agcccgttct tttaatggtg atagacatgt atcctttcac caacttacta
    11101 aaaatcaagt tgatgacata aagaaagatg atagagttta tcaagctggt acttcaataa
    11161 ctattggcag tagtaaaata aaggattctg gtatctctgt acttgtaaaa gagtatgata
    11221 aaacaggact ttctaactac ccaaaattaa tgaaattaaa atctggacat ttgcctaaag
    11281 ataaaaacga aatagcctta gatgaaaaca ctctaaagct tatgggtata aaaccaagac
    11341 taggagtgac tatacctatg aatttagata tttcactttt aaatgatacc ataccaccat
    11401 ataattacac agctaacttt aaattgagtg gcattttaga ggatgattat acaggatatg
    11461 taagtggtat agtaaatggt attgtaggta aaggtacatc agaaaatcta ttacctaaga
    11521 gatatatttt atcctctttg gattttaaaa taaaacagca agaaaagttt caagaaatag
    11581 taaatcaatt agctaaaaaa ataaatcttt ctcacaattc aattcaatat aattggattt
    11641 acttaaatgc tcttaagata cagtttgaaa aagatgaaaa tagttctaat agtgatggta
    11701 tatctatgat tatattggta tctttatttg ttgccttatt ggttttactg gcttctggac
    11761 ttgtaatcta taatatttta aaaatctctg ttacaaagaa aattaaagag tatggatgtt
    11821 taagagcaat aggagctgaa ccaaaccaga tatataagat agttatttta caaatcttaa
    11881 ttttatgtac tgttgccata cctattggag ctgtaattgg aattatctct tctaaaggca
    11941 taactggaat ggtcactaat atcttaaatc cagatatact tctagcaaat gataataaag
    12001 aaattactga gcttatacat aaaaatacaa cagcatatat gttcccatta gtattaagca
    12061 ctaatgtatc tttgattttt tcatttattt cagcattacc atcagcaata tatgcttcac
    12121 gtgtctctcc caaaattgct atggctggta gtactaccaa aatcaaaaga aaaattaaaa
    12181 gagaaaaagc aataaaaaac tttgaaagac atctagcatg gctaaactta aaaagaaata
    12241 aaggaagaac tataataact atactatcat tatttatgag tataacagta ttcgttgcat
    12301 tgagtgagtt ctctaatgta ttagatgtat ctaggtcagt aagcaattta aaagaaggag
    12361 atttttcctt aacaaatgaa atatctggtt ttgataaatc aacactagat aaaatagata
    12421 aaatgaaaaa cgtcaatcgc acttccttta taaagtactc tgaatacaaa cagggtgaaa
    12481 tagatacaga tataaatttt gaaaatagtg gtgagatgtt aaaaatcatt ggaattgacg
    12541 agcagacttt aaaagactta atgccttcta ttacagattc tatactagaa gactttaaaa
    12601 atggttctat ctgttttata aaaaatccga ttgctatttc tacaccaggt gtaaaaacta
    12661 gacatacaaa tttaaaacct aaagatagta tcacaatcaa caaaaaacaa ctagatatat
    12721 atagtacagt agataaaatg ttctttttac aaggtaatgg ctggataaat ggtgttgatg
    12781 ttattgtata taattctgtt tataacacct tgacaaataa aaacaagttc aaccagataa
    12841 atatttatgc taaagataaa tcaaaattag aacaaataag attgtctatt gaacagattt
    12901 gtgaaaataa tcctggctct cattggatat catatattga atcagataag caacttaaag
    12961 agagttttaa acaaatagaa tttctagcat gggcagttat attatttgtg ggattgattg
    13021 gtactttaaa catcattaac acaactcata caaatataaa tactaggact aatgagattg
    13081 gagttaaaag agctattggt atgagtaata ttagcttata taaaatgttt ttatgggaag
    13141 gtgtttatta tggaattttt gctgctatat ttggttcaat tgctgggtat gccagtgcta
    13201 ttattataaa catggcaact atagaaaagc ttgatttcac taatatacca attacttcaa
    13261 ttttacaagc tactattatt tctgtacttg catgtattat agctactctt attccgttaa
    13321 gaaaagttaa aaagatgaat ataattgact gtatagatat caatttataa ctattttaca
    13381 gataataata taaattaaat tatcaatgac tgtctctatt ttctttcaaa tctaactaat
    13441 aaatcttttt aactataata taagctttaa aaaaggcctg tctcaaaata gagataagcc
    13501 ttttttcatt gtcggaataa tgaaaatata tttaacttca caaaaaaaga gtgcctcacg
    13561 aattaaaaat ttcgctttga gacactcccc tttaatttaa aatatatagt taaatgctat
    13621 gccaaaattt cacacatgct ccacctgatt ttgaattttc tattttaaca gaacctccaa
    13681 gctgttccac taattgtttg acaatgtaaa gcccaagacc agaatgtcca ccttttgtct
    13741 gcctagcttc atctcctcga taaaacttat caagagcctt ttttaaatct ttagagctaa
    13801 accctctacc agaatcacaa atctcataag aaatacaatt tttttcatcc tttacagtaa
    13861 tactaatatt accacctgat ggagtgtatt gcagactgtt ggatatgata ttatcaaaaa
    13921 ttcgtgtcaa cctatccacg tcgatttgaa ttggggattg tatattcccc ttcattttca
    13981 atataagttc aacttccttt tgatgagcct gtaattcata gtcttgcacc ttttgcctca
    14041 aaaattcagg taaatttata ggaacaagat ttaattgtat atttgacttt tctaagtcag
    14101 acgtatattg catcttttgg acaagagcag cacttttttc tgtattttct cttatcactg
    14161 taagatacct atgaagtttt tcattgtcat ctgtattatt accaataagt gcatctgtat
    14221 atcccaaaat aatagaaaga ggagatttta aatcatgtgc tagagcttcc accatttcaa
    14281 cacgttcctg ctccatcttc cactgcgcag ataaagaacc ttttaattcg tctttcattt
    14341 cagaaaaggc actacaaagt ttaccgagtt cattatctga ataatagtcg atttcaaaat
    14401 caaggtcctt ttcttttatc ttcttggacg catcaatcaa tagatgtaat ggttgattga
    14461 tattctttac aaagcgctta gaaagccatc tagtaaaacc cacgatatat ataaatggag
    14521 aaaacagagc cattataata actgcaaata caaatctccc tctactattt gcaaaggtta
    14581 ttttgacttg atagaataga ataacagctc cctcaatctt tccattatcc cctttgattg
    14641 gaacagtatg gatataacca cctttacgaa cagttttatt gataaaatta ttaaataatt
    14701 cttcttttgt tttaaatagt tttttggggt tagtaccata tagaatattg ccattattat
    14761 ccacaacttg atatggcata tcatccccac gaatcgttct ttttaaacct tcttcattcg
    14821 attgtgataa caaagttatg tttttttcat tgatgtattt ttcaattcta ggaacttgtc
    14881 gctcataata gtttggtgga tagatatcct tatttaagga atgaatatac aaatagagag
    14941 caaatacata agtaatcact gtggcaacta tactggctat tataataaaa ataaaagtat
    15001 gtctaaattg ggtaataagg gattgatttt tcatttaata acctctctct ctttacattt
    15061 tattccactt atacccaata ccccaaactg tggaaatata ttctttttct ggtgtcacag
    15121 cagaaaactt agctcgtatt ttttttactc gttcaacaac agttgaggaa tcaccttcag
    15181 aatcacaccc ccatactttt tcatagattt gttctcttga gaaaacttgt cctgcatgga
    15241 gtgctagtaa ttcaacaata tcatactcta tttttgttaa atcaatattc ttaccatcaa
    15301 ttttaattgc acgttccttc atatataagc ataacttccc aaaatacaaa gtagatctct
    15361 tgttctcttc attgatatac tgtgaacgct tttccctacg cagattagct tcaatccttg
    15421 ccataagttc acgcagtcca aatggctttg ttacataatc atcccctcca aaggtcaacc
    15481 ctttgatttt gtcggtttct gattgctttg cacttaaaaa tataattggg cataaaacat
    15541 catctctaat tgcctgacat acctcaaatc cattcatttt aggcatcata atatccagta
    15601 taataaggtc aggctcctgt tttgataact ctatacctgc ctgaccatca taagctatca
    15661 acacttcatg tccttttgcc ttcaattcat cctcaagtag cattactagg tccatttcat
    15721 catcaataat caatatttta ctcaatataa caccaccttt ctcttatggg aaggtcagta
    15781 ttaaaacaat attcgtctac taataacttt tccttccctc ccacatttta aaccaaataa
    15841 cgcctcctat caagaatata atcaaaccta ttgctactac tataagctct atactagctg
    15901 tttgcatcac tttagagtaa aatgcctcag ttgaaatagt tccagcttct ttaataaaat
    15961 aaattcctgg aagcatacct agttttactg gccatgtcca tggaacaaat gcccatactt
    16021 tttcaccaac gctagttaat ccaagtattg ctgccatcaa aattccaccg atactaatac
    16081 caatagatgc acccataccc catgcaaaac tcacccaaag atgaatagct aatagtggaa
    16141 gtgtcccaat caccacaagt cctgctgctg acaggaataa ccatattgtt gctccagatg
    16201 gcactgcaat actcattcct atgcaaagta tcaacgtagc aataaatgtg catatagtta
    16261 ggcaaaacag aagaaaaaga aattttccca gatataatct aacacgagaa atacctacac
    16321 ataaaaaacc attaaaattt ccagcaagct cttcctcctg cactataaat cctgctaaaa
    16381 tacctactcc aataggaatg atgaatacag tccatactgt aaaaaatcct tcaaaagcaa
    16441 attcttgtgt acttccagat ttagttgtga gataaaaaac cacacataat gaaaaaataa
    16501 taggcataca aagagtaagc cactggacag ctgtcctctt tgctcgaagc cattctgatg
    16561 ataatagctt tatcatttgt catccctcct attgaaccaa gctgcagtaa gcgctgttaa
    16621 tactataaac acaaccaaag aaacaacaat cccaatagga atcactgaag tattcaaaag
    16681 tgggtctcca gcttctaata tagtaccgtt aggatgtatg ttgatgattg ggcataccat
    16741 tctaactgcc caactccaag gtactgcaat ccaaaatggt tttgtcgcag caaggacacc
    16801 aaatatcata cctaaagctc caactcccat acttaggaac atacctttcc atgtagctag
    16861 ccatagctga agtggaagta tagcaagaga aacaacccag catacaatac ttgcccctat
    16921 aatctgtcca aaaggaactg gaccagcttt caatattaaa ccagttataa ttgttacgac
    16981 tattaaaact aacgttgaaa taaaactgta gactgccata gctataactt tattaatcca
    17041 aagtgtcata ggagacacat tgtgtgtacg taaagcacga taatttccag cttttttttc
    17101 ctggaaagct accaaagtag caaacaatgc aaatccaata ggcagaaata aaaatgacca
    17161 ccagttaaaa attaatgcta aaagactttg ccacgcccaa gaagttgttt gagataatgg
    17221 attttgcatg agtgttgatt gcattataaa tgcatatgct gcaaaagaca ctgggaaaaa
    17281 aacaataagt ttacccataa atgttctttt atactttaaa agttctgatt gtaaagcatt
    17341 catctgtttt gtcctccttt aagaataaca tctgtaaaaa attcttctag attttcatta
    17401 gggtcaggca ttccttgaaa tagtagtcgt cctccattta taattcctat attatctaca
    17461 acttgagcaa cctctgatag aatatggcta gaaagaatta cagttatacc tttttttgga
    17521 aaagaagcaa tcaattcacg caattcttga atgccaaagg ggtcaagacc attggttggt
    17581 tcatctagta ttaacaactc tgggtcactc aaaagtgcaa tagctattcc taacctttgt
    17641 ttcataccca tagaaaattg tgaagctctc tttttacctg tatttttcaa atttactatt
    17701 tccaacactt cataaatttt atctttaggt attcccaata tttttgtatg tactaacaaa
    17761 ttttcctctg ctgtaaggtt tccatacaat gcaggggatt ctattaaaga acctattttt
    17821 gcaagagatt ctcgtttcca aggctttcta tcaaaaataa tacgaccatc tgttgggcga
    17881 agaagaccaa caagcatttt aagtgttgtg gactttcctg ctccatttgg tcctaaaagt
    17941 ccatatatac tatttcgttc aatttgtaga gaaacattgt taactgccat ttgttctcca
    18001 tatctttttg ataagttttt tgtttcaaga attaaatctt tcatattaat ttctcccttc
    18061 ttgtaatacc ttaaatctat tactaagaga atactaacat gaaaaaataa caattctata
    18121 acacctacta attttaataa aaattaaaat aaaaaataga gttaccaatt ttattttggc
    18181 aactctattt aagtttatgt tttacagtta tattagattt aagcttagtt tcattatcac
    18241 actaacttca aatttactct ataatcctta aatcaagcac taatttatta atcaaacact
    18301 aatctattaa tttatatttc tttagacatc taatatagtt tgctactaaa taataattac
    18361 ttatatcata tttatctaat cctttaaaag aagttatttc atcattaagc tcatcactac
    18421 cttctacaaa aacacaacct gtttcaaatt ccatacctac aataatctta cagccactat
    18481 aagtttcctc ttgagtatcg tacaattttt ttgcatttcc ttcatttgga attgtaaata
    18541 caataggttt taattcttta tcactggaaa tcttttgtga aaaaggcttg tttaacttaa
    18601 tattattgat aactacatgt ttaaattcct ctgaagtttc ttctactatt acatattttc
    18661 gctttaaaaa ctctattatt tctaaaacag acttagaatt tacttttaaa atacttttat
    18721 atttttcata taaagatttc cactgttcaa ttttttcctg tggtacttct tggatatgtg
    18781 tacttatttt ttcttgagat atttttttca attaaactct cctttcaata cttaaatatc
    18841 cttataaatc tcacatgact aaagttacaa ggttcctact taatagaatt ttgcatactt
    18901 aaatatgtct tattaattct ctacaggata tctccgtagt ccctacgatt cttacataag
    18961 ttacctattt taaattgtta ttagttagat tataaaaatt atttatttta tcactaatat
    19021 aatactctta aaaactttac aaatcaattt aaatttgcta ccttttattt ataacaactt
    19081 atagtacatt tctcctatgc ttttcaatat attactttta aaaggaggtt ttccttatga
    19141 ttttaaatag aactgagctt ttccgaggat attctttaaa tagatttaac gagatatgca
    19201 atatattatc agtaaataaa attaaatata agtataaagt gaaaaataat gcttactcta
    19261 aaaaaccttt ttctaatgaa ataacacttg gcaatttagg tcaaaaggaa gatttctctt
    19321 atgagtactt aatttatgtt cataaagacg attatgaaca ggcagagtct ctaataaatt
    19381 ctaagttgcg atagattatt tataaaacat gacattctgt tgtcatgttt tatatgttat
    19441 tatactttca aatatgctac tatattttca aaattgtgtg ctttaaaact agctttttat
    19501 agtaatttaa agcttaaaac taaggagact cgttatatga aaataaatat aaaatcaaag
    19561 ttaagtgaat ttattaaaca gaacaatctt tttgatgaca acagaataat atcctacctt
    19621 cctaatataa caatagaaac agacaaaata aaaactataa tgattaatga ggttgtccca
    19681 actaacacca atgacgattt ttatagtgta gataaagatg ctgattattt aaaaactact
    19741 attcctttat ttgacagtgc aggaatagaa gtatctaaca taaatgatat cctagatatg
    19801 ggtatctata taactaatgc agtaaaactt cctaaatcag aatatacaat aactcgtgat
    19861 acaattaaat tacatatgcc tattttagaa gaagaaatta aattatttaa aaacctagag
    19921 gtagtaatgt taatgggaga tgttgcaaaa aaatctttta atatgattac taaaaagcat
    19981 ataaaaaaga atgtcatccc ttccatttca acatataaac ttcgtaataa tgaactttat
    20041 tatgataatt taagagtatt tccatcatat attatgactg gtggaaacat actgattgaa
    20101 aaatcaaaat ttgaaatggc atcagaagat ataaaaaaaa tgttcgagat tataaacggt
    20161 tgatattaca aaataataaa aactaattta gccaaataat aagtgcctca aaaacttcta
    20221 tttatgaggc acttttattt tatattagtg taactatata ctattaacat aatttattat
    20281 ttatattgtt ctttttaatc tctattccat ttagtctagg taacattact ctttacaaga
    20341 ttactttata tttcttttat atctctaacg tttttattta ataaaacaat tattaataca
    20401 agtcaaatat atctatttat ctaaaaatat atcttttaca gtaatatctg gatggtgata
    20461 cttcttccta ttcgttaaaa aagatttttt tacattaata gcctcttttg gacaccagtg
    20521 aaaacaagct aggcatcttt cacactcatt accccacttt ggctttttat caactatact
    20581 tatattctct acaggacaaa cccttttaca tgtcccacat ccattacatt tattttctgc
    20641 aaaaaattta gtagttgcaa tttgcatatt cttacctact aaacgaagta caacactatc
    20701 tatatgtgac tttaaattgt tttttccttc tatatttcca atctccaagt tattgataca
    20761 ttttgcaatc tcagctaccc tattagtctg atttttcaat ctttcttctt caacatctga
    20821 aggtgttatc aaagcatttc caggcatatt gattaaaaaa ccagcagata attttttccc
    20881 ccttttttta agtaacttat ctatagtaaa taaactatgt ccagctaccc cattacaagt
    20941 ggcaatggca tatatatgag tattaatatt aaaatttaat ttctctacaa aagactttat
    21001 tatatcagga acatcagcaa aataaacagg aaaaacaatt accaatatat cttcatttat
    21061 gtctatatta ttttcttttc tatgtatagc taaaggtata acttctttac ttccatttaa
    21121 cgtttctttt aaaatctttg aaactactag cgaatttcct gttccagaaa aataataaat
    21181 cttactattc attcttatcc ctctttctat atttctacat catcaatagt taaaaagtct
    21241 cttaaaatag gatttatatt tactttccaa ttctatccaa aatatcagta aacaaaggca
    21301 attcttcatc agagatagat ttaaatgtct ctgttgcata tatacttgca atttcattta
    21361 atggttcttc taattctcta cctaaatctg ttaggaatat ttgaaactta cgtctatctt
    21421 taacatctac tttacggaca attaatccct tatttttcat aacgtctaaa attcttgttg
    21481 tattagattt atccttacat gatttttcac ataaatctat ctgagaaatt ccatcttgct
    21541 cccatagaaa ccttaataac gcataatggt cagttgttat atcatatcca ttttgtttaa
    21601 acatcttttt taaatcatct tttactttta acgaagtact tactaactta gttgtagctt
    21661 catatagttt ctcaaaatct ttcattttac ctccatttaa ataatcccct gctcctccca
    21721 tctatcaatt attcccttat attgctcaat atctttaaaa gccattggct ttaaaacagc
    21781 atttatagca ataaaattat agatttgaga aagcacaggt ggatttttct tttcctctat
    21841 gcaataaata aattttttag ataccttttg tatctttgat tctacttttt cagttatagg
    21901 attttgatta aatccagttt ttatagataa actaccacaa acataacctc ccgaatctaa
    21961 gaccatggat tttataaaag aaattgcttt tgaaccacgt gcattttcat atgtagtaac
    22021 tgctatacat ggcttacgat acaataatct ttcaagcatc atatgtgctc tatctgtaaa
    22081 caccttgaaa agtccagtta cactacttcc ataagttggg ctaccaaata taacaccatc
    22141 actcttagta attatatcat gaatatactc tactttatca ttttgattga tacacttgcc
    22201 cattttataa caatttaaac aaccaataca atatgatgga tttacctcac ttaaatcaaa
    22261 ataattaatt tttacatctg gtattaatct ttctatatct ttatacaagt aagttaaaac
    22321 ttttgatgta gctccatttt ttctagggct tccatttata actgtaatta tcatttctat
    22381 atctcctttt tagttgttat atcaacaata agtatatcaa ctatattttt agctgtcaat
    22441 ataaaccatt tatttaaagc tatacttaca cagcttaaat aaaagtttta tttaactaca
    22501 tgtgcttatt taatcaacta taaatgaatt atttttaata attgacaaac taaattaatg
    22561 ataatatact ttatgtatta caaatgtaag tagaaggagg tatagtatga aaaagttacc
    22621 acatatttca gaagcagaat atcaagttat gaaaattatt tggaaatatg ctcctatcag
    22681 cactactgaa gtaattgaaa agttggtaga aacaagtaca tggagtccta aaacaattca
    22741 aacaatgtta ttgagattag ttaaaaaagg agctttaaca tatgaaaaaa atagcagagt
    22801 attcgtttat actccacttg ttaaagaaga agaatacgta gctacagaaa gtagttcttt
    22861 tttaaatcgt ttttataatg gtactcttaa ttctatggta ctaaactttt tagaaaatga
    22921 taaactatct gaagatgata ttgaggaact gagagaaatc ttaaataaaa ggacgactaa
    22981 gggggataaa taaatatgta tgccccattc tttatacgat ttttactcag tacattaacc
    23041 ttatcaatat taattgttat aattttactt gccaaaaaag tatttaaaaa acatatttct
    23101 gcaaagtacc aatacaatat tggatttata ttgcttataa tgttaataat tccatttgtc
    23161 cctcttaaat atattaatct tggaaatgta tttaactatt tatatacttt taatcaactt
    23221 ggaagcagta ctaataggac ttctattata aaaaatagtc caaattctat aattaataac
    23281 tcaaatgcat taaacgattt ttcagtatcc ctaaaccaag ttaattttga tagtttaaat
    23341 attttattac taatatcatg gataattgga attttaatca tgatagctat tactattcat
    23401 tgcaatatta aaataaaaaa tatgaaaaaa tcaatacaaa ttttaagaga tgaggagata
    23461 gtatttatat ttgaaaagtg taaaaaagat attggtataa ataaggattt tatactatgc
    23521 aaatcaccta ttataaatac acctattaca tttggatact ttaaaccaca cattatatta
    23581 ccagataagt ctatatctaa attatcttta aaagatataa aatatatctt acttcatgaa
    23641 ttacaacact ttaaaaataa agatatactg ataaattata taatgtgctt ccttcaaata
    23701 ttatattggt ttaatcctct tgtatggtat gcatttaaag aaatgcgtat agaccgtgaa
    23761 attgcatgtg atatttcagt tttaaaaaag cttgataaag atagtcatat agaatatgga
    23821 caaactctaa taaactttgt ggataatatt tcaagaccat caaatcttac acttacatca
    23881 gatattggtg ggtcaaaaaa acaaataaaa aagcgactat tgaagataat ggattttcat
    23941 aatgaatcaa atacgttaaa attcaaaagc attttaattt ttacattgat agctttaatt
    24001 gtatttggaa atattcccaa actatctatt atggcagata tcaacgaaaa atatagacct
    24061 acaaatgaac aaactgtgta cgaggactta agtcagtatt ttaaaggttt tgatggaagt
    24121 tttgttatgt atgatttaaa atccaagcaa tatcatattt acaataaaga aaaaagtaaa
    24181 acaagaattt ctccaaattc tacttataag atttatagtg ccttattggg attggaaaat
    24241 gggataataa caagaaataa ttcacatatc ccttgggatg gaaagcatca ttctaatagt
    24301 tcttggaatg aagaccaaga cttattttct gctatggaaa actccgtaaa ctggtacttt
    24361 cagactctag acaaaaaaac agggctaaaa aacatacaaa cttatcttaa gcaaattgga
    24421 tatggcaatt atgatgtttc aggtggtatc tcaaactttt ggctagaatc ttcattaaaa
    24481 atatcaccta ttgaacaggt agaattactt gaaagttttt atacaaataa gtttaaattt
    24541 gaagataaaa atatagaaac agtaaaagat tcattgttaa tatcaaaaaa ggatggggta
    24601 tcactttttg gtaaaacagg cactgctaat ataaatggaa aagatgtaaa tggttggttt
    24661 ataggttatg tggaaaaaaa tgaaaatact tatttctttg ctacaaatat tcaaagcaaa
    24721 gattattcta atggtagttc agcatctaag ataacattat ccatattaaa tgacaaaaaa
    24781 atctataatc cttaatatat ttactgtaca ttctaaaaaa ttcacataat tttcatatta
    24841 attatcgatt aaattcatat acaaggctta ttatataaac atagaagata gtaaaactag
    24901 cttaaaaaca taatataata ccctatacaa atagtggcaa ctctccctca catcctcaat
    24961 tgttgccact atttaatttt ttgtatgaag ttaaatatat tttcatcatt tcaacaattt
    25021 gggtgcagta caatctctat tttgagacaa cctctttaat tgttttagag tttatgaatt
    25081 atttctcata ctttaaaaag attgaattac tcttgataat cttcttttgt agtcattaca
    25141 tatcacctac tactcaacac atattctttg acctattttt acatccttgt ttatatccaa
    25201 aatatttacc ttcttaccat ctggaaacaa taccattgtc aaagtagact ttcctaattc
    25261 atgtattctc tttaaatcaa cattaacaag aacatctccc tgtttaacca tatctccttg
    25321 tttaacagca atatcaaagc catctccatt taatgcaact gtatcaattc caacatgaat
    25381 taatacttct ccattagttc ctttaatccc aaatgcatgt ccacttgaaa atactgtttc
    25441 taatttacct gaaataggag aaacaatttt tccatctata atatcaatag caaaaccatc
    25501 acctaacatt tttttagaaa atgtttcatc tggtacattt tctaatgcaa caattttccc
    25561 cttagctgga gacacaaagt tttcattatt ttcattaaac actaattctt cgtcttcatc
    25621 ttcatttata gcttctttag gcactccaaa taaacatgtt acaataaagc agaatgcaac
    25681 cacaaatatt gatactaata agtatgtgat taaattatat ccatcataga tatacattaa
    25741 ataagaaggt aaaactgcta atccatatga attagattga atatgtaaaa ttgataatat
    25801 tgctgctcct aaacctgaag atgcacacat aataatcaaa ggctttaaat tatatcgaag
    25861 ctgaatccca aataaaacag gctcacttat accaaaaagt tgagatagca ttgctccaac
    25921 tgcagtttgt ttaacttgat tatttttaga ttttttcata aatgctagac atgttccaat
    25981 attcgcaaat ccatacattg cacaaagagt aataagtgca ttaaatcctg tatttgctaa
    26041 tagtgatgtt tcaatcatta cataagtatg atgtaagcca gtaataacag ctaatggata
    26101 tgtaaatcca ataataaatc ctccaattcc taaaggtaaa ccaatcaata aactgatgat
    26161 atcaaccatt tttaattcta ttgtatgcat tataggccct acacctaaca aaataactaa
    26221 cattgttatt agcataacaa agaatggtgt gaaaataagg tctaatacat taggcatatg
    26281 tttacggaac catttttcaa gattagctcc aataaatgct gtaacaatag ctgttaaaac
    26341 acttccttga cagcctacaa taggaataaa tccaaatgcc ataattgctt caacttcatt
    26401 tgatgggtca gcaacagaat atgcattagg aagtattgga gaaactaaca taagtccaat
    26461 aacaagtcca ataacaggtg ttcctccaaa taccttaaat gctgaccata caataattgc
    26521 tggtaaaaaa gcaaatgctg tttctgtaag aaccgaaaca agtgtctgaa tatacaatgg
    26581 aatatttgca gaagacattc caaataatcc aagtacatta tcattaaaca aacaaccctt
    26641 taatcccaag aataatcctg ttgccgcaat aactggaata ataggaacaa atatatctgc
    26701 tagagttctc ataactttct taaatccagt ttcattattt ttaactaatt catcttgttc
    26761 tttttttgat aaagttttca atcccatttt ttcaacttct gcataaactt tattgactat
    26821 tcccgttcct agaataattt gatactgtcc agaagtaaag aaaacacctt taacctcatt
    26881 aaccttttcc actttcttat cattaataat ttctctatct ttaaccatca cccttaatct
    26941 tgtggcacaa tgtgtaatag aaataatatt attttcacca ataatttcaa taagctcatt
    27001 tgctatttta ttatatttat tcatttttct acctcacttt caataatact gcttgaaatg
    27061 gtttcaaact cactgtttta tttagtagat ttatatcatc taaattttgg aatacaatat
    27121 catatttttc ttctgttttt atttctacaa gtttatcaga aaaattataa taacaatcaa
    27181 taactaccaa atctaattgc cttctatacg caataacatt gtcactttct atatcaatag
    27241 gttctattga accataaatc aaacaatcag aatacttact atcttgtctc aactttatca
    27301 tctttttata aaattctaaa atactttctg aattgttaat ctgactctgt gcattaatat
    27361 ctttataatt ttcaataacc tttaaccatg gtgttgcatc tgaaaaacct gcattttctt
    27421 tatctgccca tggaaatggc gttcttgcat tatctcggct tcttaaattc acaaattcta
    27481 acgcttcttc ttctgagtaa ccttcatcta ttgaacgata gtattggtca atgctagata
    27541 aatcattaaa atcatttatg gtatctcttt taaaatttgt cattcctaat tcctgtccct
    27601 gataaataaa tggtgttcct cttaaaaaga aatacattgc tcccaacatt tttactgcat
    27661 catcattcct ttcgtattgc aaaagatact ttgttgtagc tcttggttgg tcatgatttt
    27721 caataaaatt agctgcccat ccatgttcct gaacatacat ttggctatct aaaatgcatt
    27781 ttcttaaatc tggaattgtc catgaaattc ttttaaacca ctcactacca gaagcaacat
    27841 ctaagtcagc atgtttaaag tcaaagacca ttgaaaagaa accatcttct ccaataaaat
    27901 cacctagttg gtcatagcta atacctgctg cttcagcaac agtcatacaa tcatattttt
    27961 taaacgtatt ttcttttaat tcataaagca ttttttctat tccaggctga tttctaactg
    28021 tttttgtaca tttaacaaga ccatcaacac catcactttc taaactttga aaacttaaat
    28081 tctttttgat aaatgtaata gcatcaactc taaatcctgc cactcccatt tgagaccagg
    28141 tattaatcat ttggtaaagt tcacttctta atattggatt ttcccaatta aggtcaggtt
    28201 gttttttacc aaaagaatga aaataatatt cgtctctatt ctctaccttt tcccaaacac
    28261 ttccaccaaa aacagacctc cagttatttg gtaaatcgtt tcctttttta aaaatataat
    28321 aatcatgata aggactttct ggatttttta atgcttcttg aaaccaagga tgttcatcac
    28381 ttgtatgatt aagaactaaa tctaatataa ttttgattcc tctatcttta ctttctttaa
    28441 ttaactcttt taaatcttcc atacttccaa attcacttgc aatatctaaa taatcactaa
    28501 tatcataccc attatcgtcc ataggtgatt taaaaattgg acataaccac aatgatgtaa
    28561 tacctaaatc ttttaaataa tctaaacgag aaataattcc ctgtaaatct ccaattccat
    28621 cattattact atcttgaaag cttcttggat aaatttgata aacgatttct ttttgccacc
    28681 atttcttttc cataaattac tcctttttat atgatatttc ttctttttaa ttctttataa
    28741 attccattat cgaatatgtc ctcacatata gatgtcgcta tatctttaag ttgttgatga
    28801 ctatttttca ttgcaattgt aacgtctgat gcttgaaaca tgacaatatc attttgacca
    28861 tcaccaaaac atatggtttc tttttgagtt acccctaatc tttcttgtaa tctcttaatt
    28921 gctttgccct tatgaaaatc tttttgaata atttcataat actgactaga aatatctctc
    28981 tgtgctaatt ccattttatc ttgtagtata tctttcactt cgtcaaatac cttttcattt
    29041 gaccataaac aaattttatg tacatcttgt gacttatact cttcaatatt attttcatat
    29101 gttatttttt cttggatatg ttgtttattt atacaagaat tagttccttt caactgattc
    29161 attgtttcaa atatttcttt ggctttttga ttcatgaaaa ctttttcctg actctcaatc
    29221 gaaaaagcaa cttctctctt ttttaacaaa caaacaactt cctttatcaa tctttgatta
    29281 aaagattgat tataaagtaa ttcaccatga tattgaatgt aattacctcc tcctgcaata
    29341 tatccatcaa cccctaatga taaaacatca tcttgtattg tacctatact tcttccagta
    29401 caaataacaa cactgcaatg attcttttga cataaacgta tagcgtgctt tgcagattct
    29461 gggattccat atacctcatc cctaagcgta ccatctatat caagtattaa taatttgtac
    29521 aatttcatct tcctttctta ctatcaaaat cataatagca ttcaaaaaaa aagatatcaa
    29581 tattttgata tcttttaaaa aatatgttca tttttagcac aaattttcac tttcggggaa
    29641 tatgttcact ttctaaatac atcttgtatt taatataaag cagttcaatt aaaataaaat
    29701 aaggtgttgt tacatcgtag tccagttgtt tatctacaga aatagatata gattgaatat
    29761 acaggttttc atcacataat cttgctaaag gattacttat catttttgta atagaaacca
    29821 tataagttcc tttcattctc atttctttag caaaatcaat aattgtagat gtatctccat
    29881 tcaatgagat aaagaaaatc atatcatctg tttttataaa atgattaagc gcctgaatca
    29941 tatcataacc ataaacatca tatataattt tccctgttgg taagaaaatc cttttcatct
    30001 ctttaacaac tctttcctga gaataacctt ctccaaagac gattatacga tttgcctttt
    30061 tcattctttc aaacataatc gaacaatcct tcttctctat atcatctatc accttattat
    30121 aacaatccat taattggtgt ttactttgat ttttatattc tacttctgtt tcatttaagc
    30181 gtataataac tcttaattca ctatatccag gtaattgtag tttttgagca aaacgagaaa
    30241 gtgcacttgt agatatatgg tatttgtctg caaattcatc tatagaaagt ttaatacaat
    30301 cttctttatg attaagaata cactcacaga tatacttatc atttgctgta aatgaattat
    30361 aatatttatt gaaaagtcct tcaattttca ttcttttctc cttctatact ctatgtaatt
    30421 catatgaagc aaatctaata gagcataaaa tgctcctacg acttcataag atatagcttg
    30481 taatgtatca agtttttgag tttcaacata cagattatac tcacaaagtg ttgcaattgt
    30541 attattatca agcctagtta aagaaatcgt atgtatatga ttgttgataa attttgcaat
    30601 ttcaattcct gattttgttt ctccagacaa agaaatgata ataaataaat cacttttttg
    30661 aaatgattct ctcataaatt caatttcacc tatatcaaat aagtcaataa cacatttacc
    30721 tactgaaaga aatattctct ttatttcttg agctaaactt ttctgttcat tacctgtccc
    30781 ataaatataa attgtttctg catcatatat tattttacaa atatcttgaa atgatatttt
    30841 ttgtaattca ttcattaata gtcgataatt ctcgcaaaca tcatgaaaat tattatcatt
    30901 attaacaaat tctagttgat tatttttaag taaatacttt aaatcagaga atgaatctaa
    30961 tccaattttt ctacaaagcc ttaataaagt agctctagaa acattacatt catttgcaat
    31021 tttttcacac gaaaaattac ggtattctct ttgacaaatc aatatttgtt taataataat
    31081 tttatcattt tcatttaaac tattataact ttggttaact aacgattcta atctcatttt
    31141 ttccactccc taaatattat tttaatatac attagttgct ttttctagtg aagagtctta
    31201 aataataagg ataaaataat catttgattt tatttttatt aaaataaaaa taacctgcta
    31261 aaagcaggca ccaaaaagta cttatccttt cgaacatgta ctttagatat tgctttcttc
    31321 ggaagcttca tctcttcata ctctaaaata gagttttttc taactcaaaa gtattttcca
    31381 tggtagaaat tactttaatt catctgccat ttatttttta tcttatttaa taattactat
    31441 tacttgaata tttacttctt taagtaaatt tcatagttaa caaagctaaa actattatta
    31501 tagatgttaa aatacaaaat tataagtatt gttataaata tgcttacagc tacaaatata
    31561 catgatatat taaaaagaag ctgtaaatta ttatcataca tacaagcaac tatgcctcta
    31621 ttaatccatg ttaattttta ttatttaata caaggagttc catgagacat acatatccat
    31681 tcatatttta aattatccaa ttctcttata gatttcatca tctttttata atcccaattc
    31741 catggattag gataaggaac tatatttcca ttcttatttt tgactaaatc acctgcaaat
    31801 aatacatctt caaaaatcat gcagacatgc cctggagtat gaccaggagt atggataatt
    31861 tttatattcc caatcttcat attctctcca taaggttcaa catccttaat gagccttctg
    31921 gaaattgcct ttccaataaa cttcttaaac ccaggtctat ccttctctcc tataataaaa
    31981 ggtatatcct ctacatgagc ccataccttt gctcctgttt tctctttcaa taatttaata
    32041 ttagatatat gatcaacatc atgatgagtt aataaaatat gcttaatatc tgtaagttta
    32101 atgccaagtg tttttaattc tttaattata tttttcccca taaaaggaag acctgtgtct
    32161 ataagaataa tttctttatc gaacacaata aaacaatttg aaccacgagt actatctaac
    32221 attaatacat tttcttttat cttcataaat aaattcccct tatttggtat tttacctata
    32281 taattaatta ataaagttat aaatagttat aatacttgat attaatttta ttttttatta
    32341 aagtatacta taggtataca aatattatat ttacataagt ataccatcag tatacttttt
    32401 tatcaataga aaggaataat ttatatgtca gaattatcaa aaagagataa agaaaaaata
    32461 caaagagaaa atgagattat tgataaggca gaaaaattat tttgtcttaa tggatttgat
    32521 taaaaaatag ctacgcacac tcgtgacttt agtcatgagt tagtagctaa aatagtcagc
    32581 atatagggaa acctatatgt agagatagga taa
//
LOCUS       DAMJWO010000046        30991 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.047, whole genome shotgun sequence.
ACCESSION   DAMJWO010000046 DAMJWO010000000
VERSION     DAMJWO010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30991
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.047"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            27..101
                     /locus_tag="PC366_002177"
     tRNA            27..101
                     /locus_tag="PC366_002177"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="PC366_002178"
     tRNA            116..200
                     /locus_tag="PC366_002178"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="PC366_002179"
     tRNA            210..293
                     /locus_tag="PC366_002179"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            317..391
                     /locus_tag="PC366_002180"
     tRNA            317..391
                     /locus_tag="PC366_002180"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:349..351,aa:Gly,seq:gcc)
     gene            416..492
                     /locus_tag="PC366_002181"
     tRNA            416..492
                     /locus_tag="PC366_002181"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:450..452,aa:Arg,seq:tct)
     gene            502..577
                     /locus_tag="PC366_002182"
     tRNA            502..577
                     /locus_tag="PC366_002182"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:535..537,aa:Gln,seq:ttg)
     gene            586..661
                     /locus_tag="PC366_002183"
     tRNA            586..661
                     /locus_tag="PC366_002183"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:619..621,aa:Lys,seq:ttt)
     gene            664..752
                     /locus_tag="PC366_002184"
     tRNA            664..752
                     /locus_tag="PC366_002184"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:698..700,aa:Ser,seq:tga)
     gene            756..831
                     /locus_tag="PC366_002185"
     tRNA            756..831
                     /locus_tag="PC366_002185"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:789..791,aa:Phe,seq:gaa)
     gene            838..911
                     /locus_tag="PC366_002186"
     tRNA            838..911
                     /locus_tag="PC366_002186"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Met,seq:cat)
     gene            926..1002
                     /locus_tag="PC366_002187"
     tRNA            926..1002
                     /locus_tag="PC366_002187"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:960..962,aa:Ile,seq:cat)
     gene            1020..1096
                     /locus_tag="PC366_002188"
     tRNA            1020..1096
                     /locus_tag="PC366_002188"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1054..1056,aa:His,seq:gtg)
     gene            1105..1180
                     /locus_tag="PC366_002189"
     tRNA            1105..1180
                     /locus_tag="PC366_002189"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1138..1140,aa:Lys,seq:ttt)
     gene            1188..1261
                     /locus_tag="PC366_002190"
     tRNA            1188..1261
                     /locus_tag="PC366_002190"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1220..1222,aa:Cys,seq:gca)
     gene            1269..1345
                     /locus_tag="PC366_002191"
     tRNA            1269..1345
                     /locus_tag="PC366_002191"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1303..1305,aa:Arg,seq:acg)
     gene            1358..1433
                     /locus_tag="PC366_002192"
     tRNA            1358..1433
                     /locus_tag="PC366_002192"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1391..1393,aa:Val,seq:tac)
     gene            1509..1922
                     /locus_tag="PC366_002193"
     CDS             1509..1922
                     /locus_tag="PC366_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577704.1"
                     /translation="MYIVIGNEIVDSEELKIIIDENSKFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLINEQCNLSSLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKL
                     DEVDGIVKIILAVAYADLGHLKLSDVVKRLSRQVD"
     gene            2231..5662
                     /locus_tag="PC366_002194"
     CDS             2231..5662
                     /locus_tag="PC366_002194"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HDF2577705.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            5904..7832
                     /locus_tag="PC366_002195"
     CDS             5904..7832
                     /locus_tag="PC366_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDF2577706.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGVLSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLK
                     TGDTISADKDAEALEKIDFPKPQIYYAVTPKNKGDEEKVASVLNKLVEEDPTLHWYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
     gene            8285..8749
                     /locus_tag="PC366_002196"
     CDS             8285..8749
                     /locus_tag="PC366_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HDF2577707.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            8756..9250
                     /locus_tag="PC366_002197"
     CDS             8756..9250
                     /locus_tag="PC366_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HDF2577708.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            9266..10291
                     /locus_tag="PC366_002198"
     CDS             9266..10291
                     /locus_tag="PC366_002198"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HDF2577709.1"
                     /translation="MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEE
                     DHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYAFNTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            10278..12725
                     /locus_tag="PC366_002199"
     CDS             10278..12725
                     /locus_tag="PC366_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HDF2577710.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            12905..14278
                     /gene="radA"
                     /locus_tag="PC366_002200"
     CDS             12905..14278
                     /gene="radA"
                     /locus_tag="PC366_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HDF2577711.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSENLYIFAENNLSIIESYL
                     ESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDENIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            14281..15351
                     /gene="disA"
                     /locus_tag="PC366_002201"
     CDS             14281..15351
                     /gene="disA"
                     /locus_tag="PC366_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning protein DisA"
                     /protein_id="HDF2577712.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAVTNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            15440..16534
                     /locus_tag="PC366_002202"
     CDS             15440..16534
                     /locus_tag="PC366_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HDF2577713.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            16663..18840
                     /locus_tag="PC366_002203"
     CDS             16663..18840
                     /locus_tag="PC366_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577714.1"
                     /translation="MRKKIISFLATFIIILTSASQYSFADDMSTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSINENLNFGEYGSVLGSLGQSLSENGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KEAYKNNDVVFVELGDTYRLDLYKPNLNEKTYESVKDNIEKNIDVYLKNIFSMVEEND
                     TVYIASAFPSDLDYKNKRRLSPIIKLNGEGKGILSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKNYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWSIIVFSLVILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVLFVLGVFVAIDMILGSNSHLGMFVKEIYFNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILVLMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYVIVPMITLSINLTALKE"
     gene            complement(19026..19871)
                     /locus_tag="PC366_002204"
     CDS             complement(19026..19871)
                     /locus_tag="PC366_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2577715.1"
                     /translation="MNRNNFSHEIIEPIDNLDVNFKLFDDSGSYVANHWHNSLEIIYI
                     TSGDLQINMEGYTYNLKANECMFINSGIIHSTRCTYQDTSILLQVPLSFLNKYIPDFK
                     NCYFDFKVNANDNNYKKNSGKVKLILENMREIKLSSPPAANLLFTSLLFELLFELYTN
                     FKISVGNKNMKKTVLDLSKFEPVLEYTKINYKMPISINKIAKVAHLQPEYFCRKFKQY
                     MGQTYLEYLNDVRISHIYKDLINTNDTLCSILEAHGFTNTKLFYRIFKEKFKCTPKHI
                     RKKST"
     gene            20088..21254
                     /locus_tag="PC366_002205"
     CDS             20088..21254
                     /locus_tag="PC366_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HDF2577716.1"
                     /translation="MYIKGVNLGGWLVLEKWMTSSLFEGTEAEDEYYLPRQLSREAYE
                     SRIKTHRSEYITERDFATIKSMGFNSVRIPVPYFIFGDCEPFIGCVKELDKAFAWADK
                     YGLSILIDLHTVPGSQNGFDNGGISGICSWSQNPEYVAFTLNVLERLAKRYGMRHELY
                     GIQILNEPITERMWNIMNVPNRFKAVDKEMARGSKPNSLEFLRDFYIKAYKVMRPYMR
                     EENVIVFHDAFELKAWKDFMREEEFKNIVLDTHQYLMLAESDGCEQSIDSYLKYIREN
                     YAKDILQMQKYFPVICGEWSLFNSYACGIDTNGGQSPLNGIESNIDKLSKDDKRELYR
                     KIAKAQLDAWRNGSGHYYWNYKLLLDTVNEEGWIGWDSWDLGKCVAQEWYPIEY"
     gene            21276..22922
                     /locus_tag="PC366_002206"
     CDS             21276..22922
                     /locus_tag="PC366_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HDF2577717.1"
                     /translation="MIKNPILPGFNPDPCICRKGDDYYLVVSSFEWFPGIPVYHSKDL
                     KNWELYTHILTDETKIDLKKLPSSKGIWAPCLTYCEEEDLFYIVYGIMNSMNARYFDV
                     DNYLITSKDIKGEWSEPVYIHSSGFDASILHDDDGKKWIASLDWETREGYEKPGVICL
                     VEYCTKKKEIVGYPKRIWSGGTDRGCIEAPHITKRGDYYYIMCAEGGTGYGHSVTMGR
                     AKNIWRPYEKDSMNPIVTSIPGDFYERHDPDHLKPKYYNPESKLQKSGHGSYIETTSG
                     EVYLVHLTSRPFVPELRCTLGRETAIQKMKWTKDNWLRMEDESNLAKEYVSESKLEEH
                     LVSSIPSFDDFDSNVLGLQYYAPRISPLSFADVKSRPGYVRIRGQESRTSLNKVSILA
                     RKLTSVYARITTKMEFYPEVHQHSAGLIMYYDNMNYINLRKYYSETLGQSALSIIHLE
                     NGEKTEFLNTRIPIKDIPIYLRLYIQGRKSYFEWSYDEKNYQRIGKVFDTTKFSDEYC
                     KYGEFTGTFIGLTCADRVKHKHYADFDFFEYIADESKDVD"
     gene            23019..24392
                     /locus_tag="PC366_002207"
     CDS             23019..24392
                     /locus_tag="PC366_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2577718.1"
                     /translation="MNTEVNVKATTIRYEKISFFERISYGCGDLGCNIIYSAMSAFLL
                     FYYTNYADVSAAAVGSIMLVSRILDGFSDLTMGIIVDRTKSKYGKARPWILRMAIPFA
                     IAAVLLFSVPSNLGITSKLIYIFITYNLVSTVIYTAINVPYATLNSLITQNQYERGVL
                     SIFRMILATCGTLLINGLTLPLVEYFGNNLSAWTKTFFVFGIASIMVFFITFTGTKER
                     VKAVKQDRNEVIPFKIGIKSLFRNKYWIQITLCLVCIFIVFAINGGSSVYYAKFILGD
                     EKLFGPINMVSNISQIIAMFMVAPFIKKFGKRNVLIVGSIILISSNVMFIIVGQNYIG
                     VIFASAIKGIGSAGIASTMFAIVSDTIEYGEWKTGYRTEGLINSASSFGFKVGNGLGS
                     AILGAVLSIGGYVGTSATQSDLAIVSIKVCFIYLPIFITILQIIIMFFYKLDKEYSTI
                     LNELNTK"
     gene            24837..25790
                     /locus_tag="PC366_002208"
     CDS             24837..25790
                     /locus_tag="PC366_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HDF2577719.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            25828..26790
                     /locus_tag="PC366_002209"
     CDS             25828..26790
                     /locus_tag="PC366_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HDF2577720.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLKNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            26815..27801
                     /locus_tag="PC366_002210"
     CDS             26815..27801
                     /locus_tag="PC366_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HDF2577721.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGFVPEDDYVIEIGKADIKREGTDVTVITYGRMLQSV
                     EEAAETLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            27814..28860
                     /locus_tag="PC366_002211"
     CDS             27814..28860
                     /locus_tag="PC366_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HDF2577722.1"
                     /translation="MVANKIKATPAARSQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYSGKIRKCDVEKLTAKETIVSNNTSKYSE
                     KKELKIENENSSMFNTVEGIFEKPNPMRATVAKRMSESYFSAPVFTFNIEVDATELKV
                     LRAKLIDTVKESTGVKLTMTDLIVMAVSKILPNHQALNSAWTDEGIFRYKDVNIAIAV
                     GLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            29027..30757
                     /gene="lpdA"
                     /locus_tag="PC366_002212"
     CDS             29027..30757
                     /gene="lpdA"
                     /locus_tag="PC366_002212"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDF2577723.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAVIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDIV
                     EENQNIEVKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVDVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSE
                     SLKYSLSKKGINVLTKKKVSEFKEEGNNILVCIEGEVPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPTDEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
BASE COUNT        12450 a         3412 c         5941 g         9188 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atgtaaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttat
      301 ttaatttaat aaacgagcgg gaatagttca gtggtagagc gcaaccttgc caaggttgaa
      361 gtcgcgagtt cgaatctcgt ttcccgctcc aaattttatg tttatgttgt aatgtgggtg
      421 catagctcag ctggatagag caacgccctt ctaaggcgtg tgtccggggt tcgaatccct
      481 gtgcgctcac cacatatata ttggggatta gccaagtcgg taaggcacat gactttgact
      541 catgtatgcg taggttcgag tcctgcatcc ccagccaaac agtatggtct attagctcag
      601 tcggtagagc acctgacttt taatcagggt gtcccgcgtt cgagtcgcgg atagatcacc
      661 aatggagagg tgtccgagtg gtttaaggag ctggtcttga aaaccagtga cttcgaaagg
      721 ggccgtgggt tcgaatccca ccctctccgc caaatgccca gatagctcag tcggtagagc
      781 aggggactga aaatccccgt gtcggtggtt cgattccgcc tctgggcacc aaaatgtggc
      841 ggtatagctt agttggctag agcgttcggt tcatacccga aaggtcatag gttcgactcc
      901 tattaccgct actaaaattt aatgtgggcc attagctcag ttggttagag cgcccggctc
      961 ataaccggta ggtctggggt tcgagtccct gatggcccac cacattaaat taacttatgg
     1021 tgggtatagc tcagttggtt agagcgccag attgtggctc tggaggtcgt gagttcgact
     1081 ctcattatcc accccaactt atatggtcta ttagctcagt cggtagagca cctgactttt
     1141 aatcagggtg tcccgcgttc gagtcgcgga tagatcacca aaaaggcggc gacatagcca
     1201 agtggtaagg cagtggactg caactccttg atccccagtt cgaatctggg tgtcgcctcc
     1261 aataaaatgc gctcatagct caactggata gagtgtctga ctacgaatca gaaggttagg
     1321 ggttcgagtc cctttgggcg caccatatga atagcgaggg attatagctc agctgggaga
     1381 gcacctgcct tacaagcagg gggtcacagg ttcgagccct gttaatccca ccagtgcaaa
     1441 cctctagtaa aactactaga ggttttattt ttgattgaaa aagtttttat atttaggagg
     1501 taagaaattt gtatatagta ataggaaatg aaatagttga tagtgaagaa cttaaaataa
     1561 ttatagatga aaatagtaaa tttaaagttg aaaaagattt aagtaaaagc acaaaaagag
     1621 aagatgtaat agcatatcag ttaagtatag atttaaatta cctagattct cttataaatg
     1681 agcaatgtaa tttgtccagt ttatctgatg aagagaaatt tgatgaatat atgactttgt
     1741 ctgatgaact tgcactggat ttagaagagt taatgccaaa atatacaata ataaatgcta
     1801 gagcatataa attagacgag gtagatggaa ttgtaaaaat aatactagct gtagcgtatg
     1861 cagatttagg gcacttaaaa ctttctgatg tagtaaagag gctatctaga caagtagatt
     1921 aggatatgaa tatgaactat attaaaaaaa tgtataaaat cttacgtaaa gatgaaaata
     1981 attatgtaaa catagaaaaa aacagtataa aatcaagtca attgtagaaa ttttcacata
     2041 aattcatctg aaattctata aaaaatgcct taattttaat gaggtaaatc gagtttacac
     2101 agtctaaaaa ttacttatat ttataaattt atcttattaa ttaaggaact ttcttaaaca
     2161 tcttcaaaaa taaagtattt tagtctataa tctttaatat tacacaaaca ataaaggaga
     2221 agaatagagt atgcttaaaa agtttaataa aatactagtg gctaatagag gcgaaatagc
     2281 tataagaata tttagagcct gttcagaatt ggggataaaa agtgttggta tatacagtaa
     2341 ggaagataag tatggattgt ttagaacaaa agcagatgaa tcatatttga taggagaagg
     2401 taaagggcca atagatgcat atttagatat ggatggaata atagacctag caaagagaaa
     2461 aaaagttgat gctatacatc caggatatgg ttttctagcg gagaatgcag aatttgctcg
     2521 taaatgtgaa gagaatggaa ttacttttat aggaccatca tctaaggtaa tgaatatgat
     2581 gggggataag attaactcta aaaaaatcgc aaaagaagtt aatgttcaaa ctataccagg
     2641 agtagaaaaa gcaataagaa gtactgaaga agcaaaggaa gttgcaaaca aaataggata
     2701 tcctgttatg ataaaagcat ctaatggcgg tggcggtaga ggtatgagaa ttgtacatcg
     2761 cgaagaagac ttagaacttg aatatgaaac tgcttgtagt gaatcaagaa aagcttttgg
     2821 agaagatatt atatttatag aaaaatatat agctgatcca aaacatatag aagttcaaat
     2881 attaggtgat aattatggaa atatagttca cttatatgaa agagattgtt cagttcaaag
     2941 aagacatcaa aaaataatag aatatgcacc agctttttcg ttagatgata aagtaagaaa
     3001 agagatatgt gaagatgcag ttaagttatc aaaacatgtg ggttattcta atgcgggaac
     3061 attagaattt ttagtagatg caaatggtgg gcattatttt atagagatga acacaagagt
     3121 acaggttgaa catactgtaa cagagatggt tacaggaata gatatagttc aaagtcaaat
     3181 actaatagcc caaggttaca gcttagatag tgaagaaatt aatataaaat cacaagatga
     3241 tgtggaaata agaggttact ctatccaatg tagaataact acagaagacc ctaagaataa
     3301 attcatgcct gatacaggta aaattcaagt ttatagaact ggttcaggat ttggtataag
     3361 actagatgga ggaaatggat ttacaggggc aaacataagt cctcattatg atagtttatt
     3421 ggttaagaca atatcttggg atagaacatt ccaaggagca ataaataaaa ctataagatc
     3481 tataaaagaa cttagagtta gaggtgttaa aactaatgta ggattcctag ttaatgtttt
     3541 aaataatcct atattctcaa atggtaaatg tagtactaag tttatagatg aaaatccaga
     3601 tttatttgaa ataacagaaa gtaaagacag aggaacaaaa ttacttcaat ttataggaga
     3661 tgtaattgta aatgataatg cttgtaaaga aaaaccacta tttgatgcat tacatgaccc
     3721 aagaatggat aaggatggtt caaaatcaga aggaagtaaa atacttttcg ataagttagg
     3781 taaatctgca tatatagaaa agataaaaaa tgataagaaa ttactattaa cagatacaac
     3841 aatgagagat gcacatcaat cattattagc aacaagaata agaacatatg acttattaaa
     3901 agctgctaag ccaacagaaa aatatcaaaa ggatttattc tcacttgaaa tgtggggagg
     3961 agctacttat gatgttgcat atagattttt aaaagaatct ccttggcgta gattacaaaa
     4021 gctaagagaa gaaataccaa gcataatgtt ccaaatgttg cttagagcat caaatggagt
     4081 tggatataaa aactatccag ataatgtaat agaagaattt acaaaagaat ctgctagaca
     4141 aggtatagat gtatttagaa tatttgattc attaaactgg gttgaaaata tgaaaccatc
     4201 tattaataca gctttagaaa ctggaaaaat tgttgaagca actatgtgtt atacaggtga
     4261 tatactagat aagactaaaa ctaaatacaa tctagaatat tatattaaaa tggcacaaga
     4321 attagaaagc ttgggagcag atataatagc aataaaagat atgtcaggtc ttcttaaacc
     4381 atattcagct tacacactag ttaaagagtt aaagaaaaat gtaaaagcac caatacattt
     4441 acacactcat gatacaagtg gaaatggtgt agcaacttgt ttaatggcgt cagaagctgg
     4501 agtagacata attgatgctg cattagaatc tatggcagga cttacaagtc agccatcgct
     4561 taatgctata gtagaggcac ttaagaatac agagagagat acaggaatag atttatttgg
     4621 atatgatgag ttaggaaaat attataagga tttaagaaaa gtttataata aatttgaaag
     4681 tgatttaact aattcttgtg cagaaatata taattttgaa ataccaggag gccaatatac
     4741 aaacttaaaa cctcaagctg atagtttagg attagttaat agatttgatg aagttaaaga
     4801 aaaatataaa gaagctaatg aagttgtagg agatataata aaagtaactc catcttcaaa
     4861 agttgtagga gacttagcta tctttatgac taaaaataaa ttagataaag acaatataat
     4921 agaagaaggt aaaaatttat cattcccaga ttctgttgtg gattactgta aaggtatgat
     4981 tggtcaacca gaaggtggaa taccaaaaga tttacaagag gtagttctaa aaggtgaaga
     5041 agctataaca gtaagaccag gttcattatt accagcagaa gattttgatg aaatagctaa
     5101 atatctaaat gaaaagtatg atataaatgc taatataaga aatgttataa gttatgcttt
     5161 atatccaaaa gtatatgaag attatatcaa acatctacaa cattataatg atatatctaa
     5221 acttgaaagt gatgtattct tctatggatt aaataaaaat gaagaatgtg aagtagaaat
     5281 agaagaaggt aaggtattaa caataagatt agttgaaatt ggtgaagtta aggaaaatgg
     5341 atttagaact ataggatttg agttaaatgg aatggttaga gaagtagaaa taaaagataa
     5401 gaatttctct ggaaaaatta ataatgttga aaaagctgat atgaatgacc ctcttcaaat
     5461 tggagcaagc ataccaggaa aagttataaa aataatggtt aaagaagaag atgaagtaaa
     5521 agcaaatcaa ccattaatcg ttatagaggc tatgaagatg gaaactataa tagttgctaa
     5581 gactgatgga gtaattaagt caatcaaagt aaaagaagat gatatggttg aagataaaca
     5641 attattaatg ataatgaagt aatttaatta aaataaatta aaaagcactc tgaaatgttt
     5701 aataaaaaat gttttagagt gtttttattt attttaatta aatatttgtt aaaaaaaaga
     5761 ggacaattac ctccagatgt agaaataaag ctagtaagga aaatgttatc taaaaattct
     5821 aaatatagta aatattttcc ataatatttc ttaggaaata acagcaaaga taaaatacat
     5881 aaatttaaaa ggtgggtgct tatatgaagg tttatgatag taaaatgttg agaaatgtag
     5941 cagtattagg acatagcgga tgtggaaaaa caaatctaat cgaaactata gcttacacag
     6001 caaacactaa taagatacct aaattaacag acaaggtaaa tatgacttat agcatgggat
     6061 taatacctat agagtataat gattataagt ttaacttatt ggatacccca ggatattttg
     6121 actttagcgg agacgttgtg tcatctctta gagcaagtga tgcagcaata atagtaatag
     6181 atgcaacagc gcctattcaa gttggtacag agaaatcatt agaactaact gagagtattc
     6241 ctaagataat gtttataaat aaaatagata atgaaaaggc aagatacaaa gatgcaatag
     6301 caatgttaag agaaaaatac aataataaga tagttcctat gataagtcct atatacaaag
     6361 ataaaaactt tgtaaagtta cataatgttt ttgaaaacat agatgattta gaaggtgaat
     6421 ttaaggaaca agctatgagt gttaaagaag cattaatgga acttatagca gaaactgatg
     6481 accaaatatt agataaatat tttaatggag aagaactaac tacggaagag atacaaaaag
     6541 gtattattat aggtatacaa agaggtgata ttatacctgt aatatgtggt tcaactataa
     6601 ataatatagg cacaaaggaa atattagata caatatcaag ttatttagaa cctatcttta
     6661 cagaggaaag caaaccattt aggggattag tatttaaaac tatggttgac ccatttgttg
     6721 gaaagatgtc atatataaag attactgagg gtgtactttc taaggataaa gatgttttta
     6781 atataaataa aaatgtaaaa gaaaaaatag ctaatatata tacattgaga aatagtgaat
     6841 tagtagaaat agaaaaagct aaagctggtg atatagtagt tataactaaa gttaattctc
     6901 taaaaacagg agacactata tctgcagata aagatgcaga agctttagaa aagatagatt
     6961 ttcctaaacc acaaatatat tatgcagtaa ctcctaagaa taaaggtgat gaagaaaaag
     7021 tagcatctgt attaaataaa ctagtagaag aggaccctac attacattgg tatagaaata
     7081 cagagacaaa acaagcactt ttaggaggtc aaggagaact tcatataaaa acaattaaaa
     7141 ataaaatgaa agataagttt ggtgttgatg ttgaattgaa tgaccttaaa gttccttata
     7201 gagaaactat aaaaggaaca gccgatgtac aaggaaaaca taaaaagcaa tcaggtggtc
     7261 atggtcaata tggagacgta aaaataagat ttgaaagatg tgaatctgat tttgaattta
     7321 cagaagaaat atttggtggt tctgtaccaa aacaatatat accagcagtt gaaaaaggtc
     7381 taaaagactc tatgcaaaaa ggtatattag caggttatcc tgttacaaac ataaaagcta
     7441 cgctttatga tggttcatac catgatgtag actcttctga aatggccttt aagatggcag
     7501 caagtgcagc ctttaaaaaa ggtatggaag aagcgcaccc aatactacta gaacctataa
     7561 tgaaacttaa gataactgtt ccagaagaat atatgggaga tgtcatgggt gatataaata
     7621 agagaagagg aaaaatattt ggaatggaac cagatgacaa agggaaacaa ataatatttg
     7681 cagaagctcc acaagcagag acatttaaat atgcaataga tttaagagca atgacacaag
     7741 gtagaggata ctttgaaatg gaattagaga gatatggaga ggttccatca cagtttgcag
     7801 aaaaaataat tgggttagct actgcaaagt aatgaacaaa ataaatagaa aaataattaa
     7861 tatatattat taaaaatatt tttagggttt taactaggta taggtttatg ttaggtaaac
     7921 ttatacctag tttttataca tttttgatga ataaaaaaat atataatact ttcttaaatg
     7981 ttttaataaa aagaaagtat ttttttatta ttatttttac aaatgtttag taataaagat
     8041 gagaaggtat atttaaaata taaagtattt aaagttctga aatctaatca tgaagcaaaa
     8101 aattagcatt tggttatcaa taaatataat aaataaaaac tcataattaa tgaaagaata
     8161 aattcatatc taaatttcta taaaaaattt aaatttatac aatttagggc tttaaaaatt
     8221 taaataatag gtgtaaaata atagtcaaag aaagtcaaaa ataaaaaggt gtgtggtgat
     8281 attaatggca actatgacag atataattga aaaatttatt aaagatttga tggaagaaga
     8341 taatagcata caaattcaaa gaaatgaact agcaaacttg tttagttgtg caccatcaca
     8401 aataaattat gtcttaacaa caagatttac aatagataga ggatattaca ttgaaagtaa
     8461 aaaaggtggc ggaggatatg ttcaaataga aaaaatacga aaaagtaaag atggacatat
     8521 tagagaacta ctaaatgaaa aaataggaag tcagatatcc tataaaaaag caaaggaatt
     8581 attagaaggt ttaaaagagt cggatttgat taacgaaaga gaattaaaat taatattata
     8641 tgcaatagat gataaatcat tgtgtatgcc aatatatgaa ttaaaagaga aggtaaggtc
     8701 taatatttta aagaatataa taataggatt atttagtata gaggagtgat aatttatgct
     8761 atgtcaaaaa tgcaataaga ataaagcatc tgtatattat aataagatag tcaatggaga
     8821 aaaaacagag atgtatttat gtagtgagtg tgcaaaagag aatacagaaa tgaattttaa
     8881 cttagatatg cctttttcaa tgatggatat attttctaat ttaggttttc aacctaaaaa
     8941 agaacttgag gaaaagctag tttgtcctaa atgcaataca acatatagtg agtttaagaa
     9001 taatgggaga tttggatgta gtgaatgtta taatgcattt agtagtcaag taaatccaat
     9061 gcttcaaaat atacatgggc atatagaaca tacaggaaaa gcacctaaaa aatcttttta
     9121 taagataagt gtagaaaatg agattaaaga actaaaagaa gatttagata gagctataaa
     9181 aaatgaagag tatgaattag cagctcaatt tagagataaa attaaatatt taaaaggttc
     9241 tattgactaa gattggagtg atattatgaa agagaacata gtcatgaaat caagagttag
     9301 gctagctaga aatttaaata actatccatt tccaaataaa ttagataaag aatgtgccat
     9361 ggaaataata gaaaaagtaa aaaatgcgtt tattaattct aacttagaac aaaaagaaga
     9421 atttgatttc tataaaattg aagatttaga ccaatctaaa aaaatgctta tggttgaaga
     9481 acatataata agcccagatt tagcagaaaa tgataaaagt gcagttatag taaaaaaaga
     9541 taaaactata agcataatga taaatgaaga agaccatata aggatacaaa ctatatgtga
     9601 tgatttaaac ttagaatatg catatagtgt agcaaatgaa atagatgatt tgttagaatc
     9661 aagtttagaa tatgccttta acacaaagct aggttatcta acatcttgtc caactaatac
     9721 aggaacagga atgagagctt ctgtaatgat gcatttacca gcattaagtc aactaggcta
     9781 tatggatgaa ctttataaaa tttcatcaca aataggtata gcaattagag ggatatatgg
     9841 agaacgaaca gaagcattgg gaaatatata tcaaatatct aatcaactta cacttggaag
     9901 aacagagtct aatattatag aaaatgtaag tggacttaca aaagatgcaa tttcaaaaga
     9961 aataaaagct agagaaatat tgcaaaaaaa attaggtata aaactagaag ataaaatatt
    10021 tagatcgata gggacacttg aaaattcaag agtaatgagt agcgcagagg caatgagcca
    10081 tctatcaaat ataaaaatgg gaatagaaat gaactatata gataaactag atttaagggc
    10141 tatagaacaa cttatgatag gtatacaacc agcgcatcag tcaataatgt ataagagtga
    10201 tgatgttgag aatagagata taaatagagc aacatatatt agagaaactt tggaaaaatt
    10261 aagaggaggg atgaattgtg aacttcaata gatttacaca aagagctaaa aaggcaattg
    10321 atttagcgtt tgaatctgct aaaagtctag gacacaatat tgttggaagt gaacatatac
    10381 ttttaggtct tttaagagaa gaagaaggta tagctgctaa agttctaagt aaagttggat
    10441 ttacagaagc ttatttagaa ggcaaaatag ttgatatgga aggtaaggga gaagaaatct
    10501 cagaagatat agtattaagt ccaaggagta aacaaatact tgaattatca ggaatgtttg
    10561 caaataaatt aaaaacaaat tatattggga ctgagcatat attattagca attattcaag
    10621 aaggtgaagg aatagctaat aagattttaa attatgctgg agtaaatgat aggactttag
    10681 cccaattaac aattgatatg atgggtatta gtgataaaaa tcaatacaaa gcagagaata
    10741 gttacacggg caaccagaat caagcagaat ctaaagtact tgataagtat ggaagaaatc
    10801 ttacactata tgcaaaacag aataaaatag accctgtaat aggtagagaa aaagaaatac
    10861 aaagagtaat acaaatatta agtagaagaa ctaaaaacaa tccagtgttg ataggagacc
    10921 caggtgtagg gaaaacagcc atagctgaag gtctggctac aaatatagcc ttaggaaatg
    10981 ttccagaaac actaaaaaac aaaactttat actctttaga gatgggttca ttattggctg
    11041 gggctaagta tagaggagaa tttgaagaaa gaattaaaga agttgtagat gaagttgtta
    11101 aaaatggaaa cataatctta tttatagatg agatgcacac aataataggg gctgggtcta
    11161 ctggagaagg ctctatagat gcttcaaata tattaaagcc agccttggca agaggagaaa
    11221 tacaagttat aggtgcaact acaattgatg aatatagaaa gcatgttgaa aaagattctg
    11281 ctctagaaag aagattccaa ccagttatgg tagatgaacc aactaaagag gactcaataa
    11341 aaatattaga aggattaaga gataaatatg aagctcatca taaagttaaa ataactgatg
    11401 atgctataaa ggcagctgta gaattatcaa ctagatatat atcagacaga tatctgccag
    11461 ataaagctat agacttgatt gatgaagctg catcaaaagt aagattaaaa gaaaatacac
    11521 ctccttcaga aataaaaaaa ttagaactag aaatagaaaa tatagataaa gaaaaagaag
    11581 aagcagtaag atgtcaagac tttgagaaag cagccaaaat aagagatgaa caaggtctac
    11641 ttaaaaaaca attagaagat gttagagaaa gatggaacaa gtcatctaaa cattcagatt
    11701 tagttgatgg agaagttatt gctgaagtag tgggcttatg gacaggaata ccagttaata
    11761 aaattcttga agaagaggct gatagacttt tgagacttga ggaaatactg cacaatagag
    11821 ttataggtca agaacaagca gtaaaatcta tttcaaaggc aatcagaagg tcaagagcag
    11881 gtcttaaaga ccctaataga ccaattggtt catttttatt tttaggtcca acaggagtag
    11941 gtaaaacaga attatctaag gcattagcag aagtgcaatt tggagatgaa aatcaaataa
    12001 ttagaataga tatgtctgaa tatatggaaa aacatgctgt gtcaagaatg ataggttcac
    12061 ctccaggtta tgtaggtcat gatgaaggtg gtcaattaac tgaaaaagta agaagaaatc
    12121 catattcagt tatcttattt gatgagatag aaaaagctca tccagatgta tttaatattc
    12181 tgttacaaat tctagatgat ggtagactaa ctgattcaaa aggaagaact gtagatttta
    12241 agaatactat tgtaataatg acatcaaatg ttggagcatc tacaattggt agacaaaaaa
    12301 ctttaggatt tagtatagct aaaggagacg aagaagaaaa atctcaatat gaaaaaatga
    12361 aagaaaatat aatgggtgaa ttaaaacaaa gattcagacc agagttttta aacagaatag
    12421 atgatataat tgttttccac tcactaaatg aaaatcatat atcaaaaata gtacttttaa
    12481 tggcagcgaa actacaagag agattaaaag aaatggatat aaaattagaa atgagtgatg
    12541 aggctgttaa attaatttct aaatctggat ttgacttaga atatggagca agacctctta
    12601 aaagagcttt acaaaaagag ttggaagatg agctatctga agcaatctta aaaggtaatg
    12661 tgaaaaaggg aagtaatgta gtagcaaaag tcaaagatga aaaaatagtt tttgaaacta
    12721 aataatttaa tagagttgca ttttaaaata ttgcaaatat aagttttata atctaaacaa
    12781 aattttaagg gcaatgaatc tataataatt cattgtcctt aattatttta tttaatcttt
    12841 acatattgtc tttcagatat gctaaaatta tagtatagaa taaaaaatta aggatgataa
    12901 aagtatggca aaaataaaaa caaaatatgt atgtcaatct tgtggatatg aaacagctaa
    12961 atggcttggt aaatgtccag aatgtacaaa atggaataca tttgtagaag aaatagacca
    13021 aaaaagcacc aaaaaagagg tctttataat agataaatct tcatctaaac cagtcagtat
    13081 aaactcaata gaaagtaaag aagaagagag gtttacaaca gatataaatg aattagatag
    13141 agtgcttgga ggaggtatag ttaaaggctc tttagtgctt gttggtggtg accctggtat
    13201 aggtaaatca acacttttaa tccaagtatc tagtaatgtt gccaatttag gaaaaactgt
    13261 tttatatata actggagaag aatcagaatc tcaaataaaa atgagagcta aaagattagg
    13321 tattaactca gaaaatttat atatatttgc tgaaaataat ttaagtataa ttgaatctta
    13381 tttagaaagt gtaaatccag aattaataat tctagactca attcaaactg tcttcagtcc
    13441 agaaatatcc tcggcaccag gaactgtcag ccaaattaaa gaaggtactt caaaattcat
    13501 gaaaatttct aaaaaaatgg gaatttcaac gttcatagtt gggcatgtta caaaagaagg
    13561 ttcactagca ggaccaaaat tattagagca tatggttgat actgttctat attttgaagg
    13621 agaaagatat aatacttata gattagtaag agctgttaaa aatcgatttg gttcaactaa
    13681 tgaacttgga gtatttgaaa tgagggattt aggattagta gaacttgata atccatctaa
    13741 aattttaatc tctgaaaaac caaaagatgt agcaggttca gtaataatat ctactgtaga
    13801 aggtacgaga ccaatgttac ttgaattgca agcattagtt tctcctacaa gttttggtat
    13861 accaaaaaga acatctacag gagtcgatta caatagagta ggtatgttat tagcagtatt
    13921 agaaaaacgt gttggtttgc aaatacaaaa tcaagatgtc tatataaaca tagttggagg
    13981 aataaagata aatgaaccct caattgattt agggatagcc atttctgtag catctagttt
    14041 tagaaatata ccgatagatg aaaatatagc tgttacagga gaagtgggac ttacaggaga
    14101 agttagagca gtaagcttta tagaaaagag aatagctgag tgtaaaaaac ttggatttaa
    14161 aaagatagta gttcctagaa gtaattatga tgttgtaaaa gagaccaaag gcatagaaat
    14221 atggccagta gataacttaa gacaagctat aaatatagta cttgggagga atcaataaat
    14281 atggagaatt ttctagataa taaaaatatg ctatatgcat taaaaatgat atctcctgga
    14341 actccactta gattaggtct aaacaatgta ctaagagcta agactggtgg attaattgta
    14401 attgcaacaa acgaagatgt aatgaaaata gtagatggag gatttgctat aaatgcagaa
    14461 tattcaccat catatctata tgaattagct aaaatggatg gagctatagt tttaagtggt
    14521 gatgtaaaga aaatattatt tgctaatgca caacttatac ctgactattt tatagaaaca
    14581 tcagagacag gaacaagaca tagaacagca gaaagagtag caaaacaaac tggtgctata
    14641 gtcataggaa tttcacaaag aagaaatgtt ataacagttt atagaggaaa tgagaagtat
    14701 gtagtcgaag atatatctaa gatatttact aaggcaaatc aggctataca aactctggaa
    14761 aaatataaga cagtattgga ccaagctgta acaaatttaa atgccttaga gtttaatgat
    14821 ttggtaacta tttatgatgt tgcattagtc atgcaaaaga tggaaatggt aatgagagtt
    14881 acaagtataa ttgaaaaata tgtgatagaa ttgggtgatg aaggaacttt agtaagtatg
    14941 caattagaag aattaatggg tacaaccaga atagaccaga aattaatatt caaagattat
    15001 aataaagaaa acacagaaat aaaagaactt atgaaaaagg tcaaaaattt aaattcagaa
    15061 gaactaatag aattggtcaa tatggcaaaa ctattagggt atagtggttt ttcagaaagt
    15121 atggatatgc ctataaaaac aagaggttat aggattctta gcaaaataca tagactacca
    15181 acagcaataa tagaaaactt agtaaattat tttgaaaact ttcaacaaat tttagatgca
    15241 tctattgaag aattagatga ggttgaagga ataggtgaaa taagagcaac atatataaaa
    15301 aatggactca taaaaatgaa acaattagtc ttattagata gacacatatg atgaatttta
    15361 aatgaatttt actacttttt tcttgaatat aatatacact ttggtctata atagataagt
    15421 ataactaggg ggtgaagcat tgataaggaa agtaacaaga atattgttta ttttacttgg
    15481 atttacaata ggtataacaa cctatttaac attaatgaaa gattttgaaa tattaacatt
    15541 tggaaaagaa acatatggtt atatcgcagc tgtagtagca ggtataataa tagccatttt
    15601 aggatatctt atagaaccat gggttgtaaa taaagtaaaa gaaattgcta aaatagtgga
    15661 taaagaattg tcaaaatatc ctcagactga tatattgtta gggtctatgg gtcttatagt
    15721 aggatttgtt attgcgtatt tattaagtgg attagtaaat agaataccaa tagtaggtgg
    15781 aatactatcc ttactattat atttattcct aggatatctt ggaatgaaag ttgcgcttaa
    15841 aagtaaaaat gatttattta atattggaaa actaggaaga ttagcaaatc ctattaagga
    15901 taaagataag gataaagaaa ataaaaaaga agtaaaagcc attcctccaa aagtattaga
    15961 tacaagtgta ataattgatg gaagaatagc tgatatttgt aagactgggt ttatagaagg
    16021 aaaacttatt attcctgctt ttgttttgga ggaactaaga catattgcag attcttcaga
    16081 tgatttaaaa agagtaagag gtagaagagg tctggatata ttaaatataa ttcagaaaga
    16141 attaaatata gaagttgaaa taagtgagag agactttgat gatatagcag aagttgatag
    16201 taaattatta aagcttgctc aggttttaaa tggaaaagtt gttacaaatg attataactt
    16261 aaataaagtt gctcaattcc aaggtgttga agtattaaat ataaatgagt tagctaatgc
    16321 tataaaacca gttgctatac caggtgaaga tatggttgtt caagtggtta aagaaggaaa
    16381 agaggctcaa caaggtgttg catatctaga tgatggaact atgatagttg ttgatggagg
    16441 aagaaaatat atgaatgaga ctataaaagt actcgttact tctgttcttc aaactcctgc
    16501 aggtagaatg atatttgcaa aacctaaaaa ttaatatgtt caaagaaacc tataatttgg
    16561 gctgtttatt ttaaatagat ggtccaaatt tatttattta taacgataat gtttaatgta
    16621 ttcttaaaga tggggattta aatcagaaag cagggagaat ttatgagaaa aaagattata
    16681 tctttcttag caacatttat cataatatta acatcagcaa gtcagtatag ttttgcagat
    16741 gatatgtcaa cacgtggaaa agtaatattt atagatatga atagaactag tatgagtaat
    16801 atgttaagaa taaaatcatt aagagaagaa ctagacaata gagggtatat tggcttgatg
    16861 aatataagag gcgataaagg aagtgatgat agaaggtcat atgctagtat gggtgctggt
    16921 ggtagagcta atgtggctaa tgaagaagat attaattttg aaagctcgag taaggataga
    16981 aatatagttt ttgaatcagc tacaggaaaa agtgcaaaag gtataaataa tttaactata
    17041 aataagtcta taaatgaaaa tttaaacttt ggagagtatg gttctgtatt agggtcatta
    17101 ggacaaagtt tatctgagaa tggattaaaa gcatctgtat tgggtaattc agatataatt
    17161 gaaaatggtc aacttataaa aaatagaaac ttatgtctaa ctgcaatgga tgaatatgga
    17221 agaataccta atggaaatgt agatactata aataaaaaag acttatctat gccttatgga
    17281 atatcaactg attatgataa attgattgta gagaccaaag aagcttacaa aaataatgat
    17341 gtggtttttg tggagcttgg agacacatat agattagatt tatataaacc aaatttaaat
    17401 gaaaaaacat atgagagtgt gaaagataac atagaaaaaa atatagatgt atatttaaaa
    17461 aatatatttt ctatggttga agaaaatgac actgtctaca tagcaagtgc atttccaagt
    17521 gatttagatt ataaaaataa aagaagactt tctccaataa taaaattaaa tggagaaggg
    17581 aaaggtatat tatcatcttc aactactaga agagaaggta ttgtaacaaa tttagatgtt
    17641 ggggttgaaa tattagacaa ctttaatata aaaaatcaaa atatggttgg aagaaaatat
    17701 gaacttatta acagagatga taataaagaa tttttgatgg atgaatatca aaagatagta
    17761 tctatttcaa gcataaggtc tacaatactg aatggttttg taagtatagt tttcttgtca
    17821 tggatagttg ctatgattgc aattttattt agaaagcata tatcaaaaaa ttataaagaa
    17881 acaacatttt ttatattaaa ggaactttta aaaataggaa tagtaatgcc actgtcattt
    17941 atgataacac caataatgaa tttcaaaaca ccattagcaa tatctttagg aataattata
    18001 ataacactta ctatatatct tataagtaaa gttttaataa agaatgattt aaaaaacatg
    18061 ctgtttttta ctggattaac catagtaatt atggttattg atgctgggtt tggctcatat
    18121 ttaatgaaaa gcaatgttat gagttatgac tgtataattg gagctagata ttatggagtg
    18181 ggaaatgagt atcaaggtgt ggcaatcggt agtgcaatat ttacatttgc aattttactt
    18241 acatataaaa atataccaaa gtggtctata atagtttttt ctttggttat cttaattaca
    18301 agtgcatctc caattatggg agcaaatgtt ggaagtgcta tttctgaatg tgttgcattt
    18361 ttactattta tactattgat atataatgtg aagatagact tcaaaaaaat tgtattatta
    18421 ggtatagcag tattatttgt attaggagtt tttgtagcaa tagatatgat tttgggaagt
    18481 aattcacatt taggtatgtt tgtaaaagaa atttacttta atggaccagg agaaataata
    18541 caaacattta gtagaaagat agagatgaat ttaaagctag ctcaaaccag tgcatgggta
    18601 aatatactgt taactggaat aggtgtaatt ttagttctta tgattaatca gattagatac
    18661 tttaagcaac tgatggatga gtatccaatt gtatttaaag gatttatagc atcaatagca
    18721 ggatgtttag taactctttt agtgaatgac tctgggattg tgtcatcagc tacagccttt
    18781 atttatgtaa ttgtacctat gataacatta agtataaatc tcacagcatt aaaagaataa
    18841 gtactgtatg aataatatgt aaatatgaac acattaattt aacttcttta tttacaaaat
    18901 aaagaagaaa gtttataaaa aataaattat aataaaaaag agtttacctc aaaattgatt
    18961 attctaatca aattttaagg taaacttttt ttattataaa gataaataac atataacctc
    19021 atattttagg tagatttttt tcttatatgt ttaggagtgc atttaaattt ttccttaaaa
    19081 attctgtaaa ataattttgt attagtaaat ccatgagctt ctaatatact gcataaggta
    19141 tcatttgtgt taattaagtc tttataaata tgagaaatac gcacatcatt taaatactct
    19201 aagtaagttt gtcccatata ctgtttaaat tttctacaaa aatattctgg ctgtaagtgt
    19261 gctaccttag cgattttgtt aatagaaata ggcattttgt aattaatctt tgtatattct
    19321 aaaactggtt caaattttga caaatcaagt actgtttttt tcatattttt attacctaca
    19381 gatattttaa agtttgtata taattcaaat aaaagttcaa ataataagct tgtaaagagc
    19441 agattagctg caggaggaga gctaagttta atttctctca tgttttctaa tataagttta
    19501 actttacctg aatttttttt atagttattg tcattggcat taaccttaaa gtcaaaatag
    19561 caatttttaa aatcagggat atatttgttt agaaaagaca atggtacttg caataatata
    19621 gaggtatctt gataagtaca tctagttgag tgaataattc cagaattaat gaacatacac
    19681 tcattagctt ttaaattata agtgtaaccc tccatgttaa tttgtaaatc accagaagtt
    19741 atataaatta tttctaatga gttatgccaa tgatttgcta cataactacc actatcatca
    19801 aatagtttga aattaacatc taaattatca ataggttcaa ttatttcatg tgaaaaatta
    19861 tttctgttca taataatatc ctccttataa ttttaaatta taaatagtaa atttataatg
    19921 ttcaatatta aaaagataat atagactaat aaattagata ataaacatac ttaagaaaac
    19981 ggataaaatc aaatataata actgtatatt aaaataactt aaaaaaatta ttttattata
    20041 agtgcaaaat atacctattt aaataagata agaggggagg attttatgtg tatataaaag
    20101 gtgtaaattt aggaggttgg ttagttttag aaaaatggat gacctcaagt ttatttgaag
    20161 gcacagaagc tgaagatgaa tactatttac caagacagct ttcaagagag gcatatgaat
    20221 ctagaattaa gactcatcgt agtgaataca tcacagagag agattttgca acgattaaat
    20281 ctatgggatt taattcagtt cgtataccag taccatactt tatttttgga gattgtgaac
    20341 cattcatagg atgtgttaaa gaacttgata aagcatttgc ttgggcagat aagtatgggc
    20401 ttagtatatt gatagactta catacagttc caggaagcca aaatggattt gataatggag
    20461 gaatatcagg tatatgtagc tggtcacaaa atccagaata tgtagcgttt acattaaatg
    20521 tattagaaag acttgcaaaa cgttatggga tgagacatga attgtatgga atccaaattt
    20581 taaatgagcc tataacagaa agaatgtgga acataatgaa tgttccaaat cggtttaagg
    20641 ctgtagataa ggagatggca agggggagta aacctaattc attagagttt ttacgtgatt
    20701 tttatataaa agcatataag gtaatgcgtc cttatatgag agaggaaaac gttatagtgt
    20761 ttcatgatgc atttgaatta aaagcatgga aagactttat gagagaggaa gaatttaaaa
    20821 atattgttct agatacacac caatatttga tgttagctga atcagatgga tgtgaacaaa
    20881 gtattgatag ctatctcaaa tatattagag aaaattatgc taaagatatt ttacaaatgc
    20941 aaaaatattt tcctgttata tgtggggagt ggagcttatt taattcatat gcttgtggta
    21001 tagatacaaa tggaggtcaa tcacctctaa atgggattga atcaaatata gataaattat
    21061 caaaagacga taaaagagaa ttatatagga agatagcaaa agcacagctt gatgcatgga
    21121 gaaatggaag tggtcactac tattggaatt ataagttatt actagataca gttaatgaag
    21181 aaggttggat aggatgggat agttgggacc taggcaaatg tgtagctcaa gaatggtatc
    21241 ctatagaata ttaaactaaa attggaggaa aagatatgat taaaaaccct atacttccag
    21301 gttttaatcc agatccttgt atttgtagaa agggagatga ttattatctt gtagtttcat
    21361 cttttgaatg gtttccaggt atacctgttt atcactctaa agacttaaaa aattgggagt
    21421 tatatactca tattttgaca gatgaaacaa aaatagattt gaagaagctt ccttcatcta
    21481 aaggaatttg ggcaccttgt ttgacttatt gtgaagaaga agatttattt tacatagttt
    21541 atggaattat gaactctatg aatgcaagat attttgatgt tgataattat ttaattacat
    21601 caaaagatat aaagggagag tggagtgaac cagtatatat acactcatca ggttttgatg
    21661 cgtctattct tcatgatgat gatggtaaaa agtggattgc atcattagac tgggagacta
    21721 gagaaggata tgaaaaacct ggtgttatat gtttagtgga atactgtaca aaaaagaaag
    21781 aaatagtagg atatccaaag agaatatggt cagggggaac tgatagaggt tgtattgaag
    21841 caccacatat aacaaagcgt ggagattact attatataat gtgtgcagaa ggtggaactg
    21901 gatatggtca tagtgtaact atgggaaggg ctaaaaatat atggagacct tatgaaaaag
    21961 attcaatgaa tccaattgta acttcaattc caggcgattt ttatgaaaga catgaccctg
    22021 accatctaaa gcctaaatac tataatccag aatcaaaact tcaaaaatct ggtcatggaa
    22081 gctatataga aacaacatca ggtgaagtat atttagttca tctaacatct agaccatttg
    22141 taccagagtt aaggtgtact ttaggtagag aaacagctat tcaaaaaatg aaatggacaa
    22201 aggataattg gcttcgaatg gaagatgaaa gtaatttggc aaaagaatac gtatcagaaa
    22261 gtaaactaga agaacattta gtttcatcta taccaagttt tgatgacttt gattcaaatg
    22321 tattaggttt acagtactat gctcctagga tttcaccatt atcatttgca gatgttaagt
    22381 ctagaccagg atatgtaagg attagaggtc aagaatcaag aacatcatta aataaagtaa
    22441 gcatattggc aagaaaatta acttcagtat atgcaagaat aaccactaag atggagtttt
    22501 acccagaggt acatcagcat agtgcgggtt tgataatgta ttatgataat atgaattata
    22561 taaatttaag aaagtattat agtgaaacat tgggtcaaag tgcactatca ataatacatc
    22621 ttgaaaatgg agagaagacg gaatttttaa atactaggat accaataaaa gatataccaa
    22681 tatatcttcg tctgtatata caaggtcgta agtcatattt tgaatggagt tatgatgaaa
    22741 aaaactacca aagaatagga aaggtatttg atacaactaa gttttcagat gagtactgta
    22801 aatatggaga atttacaggt acgtttatag gattaacttg tgcagatcgt gtaaagcata
    22861 aacactatgc tgattttgat ttttttgaat atatagcaga tgaatcaaaa gatgtcgatt
    22921 aataaaatca ttactaaaat tttcagagca aaggtaaatc ttatgctctg aaataagaaa
    22981 cattagaagg caaatcttac aaaaaggagt atggtattat gaatacagaa gttaatgtta
    23041 aagcaactac gattagatat gaaaagattt cattttttga aagaatttct tatggttgtg
    23101 gggatttggg gtgcaatatc atatactcag ctatgtcagc atttttgctg ttttattata
    23161 ctaattatgc agatgttagt gcagcagctg taggtagtat tatgcttgta tctaggatac
    23221 tggatgggtt tagtgactta acaatgggaa ttatagtgga tagaactaaa tccaaatacg
    23281 gtaaggctag gccttggatt ttgagaatgg cgattccttt tgctatagca gcagtattat
    23341 tattttctgt tccatcaaat cttggtatca cttctaaatt aatttatatt tttattacat
    23401 ataacttagt ttctactgtt atttatacag caatcaatgt accctatgca actctaaatt
    23461 cacttataac tcaaaaccag tatgaaagag gagtattaag tatatttaga atgatattag
    23521 ccacttgtgg taccttacta ataaatggac ttacactacc tctagttgaa tactttggaa
    23581 ataatttatc agcatggact aaaacattct ttgtatttgg aatagcatct ataatggtat
    23641 tttttataac atttactgga accaaggaaa gagtaaaagc agttaagcaa gataggaatg
    23701 aagtaatacc atttaaaata ggtattaaat ctttatttag aaataagtac tggatacaaa
    23761 taacattatg tttagtttgc atatttattg tatttgcgat aaatggtggt tcatccgtat
    23821 attatgcaaa gtttattttg ggagatgaaa aattatttgg tcctataaat atggtttcaa
    23881 atatatccca aattatagct atgtttatgg ttgctccttt tataaaaaaa tttggaaaaa
    23941 gaaatgtatt aatagtaggt tcaataatat taatatcgtc aaatgttatg tttataatag
    24001 ttggacaaaa ctatatagga gtaatatttg caagtgctat aaagggaata ggaagtgctg
    24061 gaatagcatc aacaatgttt gctattgttt cagatactat tgaatatgga gaatggaaga
    24121 ctggatatag aactgagggg cttataaata gtgcatctag ttttgggttt aaagtgggaa
    24181 atggattagg ttcagcaata ttaggtgcag tattatcaat tggtggttat gtaggaacat
    24241 cagctactca aagtgattta gctatagtat caataaaagt atgttttata tacctaccta
    24301 tatttataac aatattacaa attatcataa tgttttttta taagcttgat aaagaatata
    24361 gtactatact taatgaatta aatactaaat aatgaaaaag tttcttataa agtcttaagt
    24421 ttaattaagg tctattgtaa atgttcccta taaaaactat tatatattta tgattattga
    24481 agaattttta gagaagcgaa taataaaaat ataagaagac tttaaatgat gaaatggttg
    24541 gtcttttaga aatgatttaa taagttattt ttatttaaag cattataagt ggacaattaa
    24601 tttttaattt atggagatga tatttaacaa ttagaagtaa tatataatat gcgctaagaa
    24661 gcaatttttc aactatttat gaaggtggtg gtacaagaaa agtatcacct tttttttgtt
    24721 atacaaaaaa acagttgact ttttatatga accccttcta taatgttact gaaattaagt
    24781 aaaatgattg aacaaatgta aagataattg aaaagcttga ttttggagga aatcaaatga
    24841 aaaaaattgg agacttaaga ttaatgatga agtgttgttc actttattac gaagataatt
    24901 tgaatcaaca ggaaatagca aatcaattgg gaatatcaag accaacaata tcaagaatat
    24961 taaaagaagc ttttgaacaa ggaatagtaa aaatacagat agttgatgtt ttgaaaaatg
    25021 attaccaaaa aatagagaga agtttggaga gaaaatataa attaaaagaa gtaatagtag
    25081 tagatgataa acaagatgca ctaacacaaa aacaagaact agcaagagct gtatctgaat
    25141 atttaactag agtagtaaag gaaaatgata taataggtgt ttcaatagga acaacactaa
    25201 aagaaatacc aagatatgtg gaaaaaagta actgtaaaaa tgttacattt atacctctat
    25261 taggagggat tggagacaat gaaatagata ttcatgcaaa tcaaatagca gtaagtctag
    25321 cgagggcttt tggaggtgat tttaaattat tacatgctcc agctgttatg tctgacttgt
    25381 ctacaaaaga gaaactttgc aaagacgaaa aaattaaaga agtactagat ttaatagata
    25441 aaacaactat agcaattgtg ggtataggaa atcctatgag tttaaactca acaataatgg
    25501 cttctggata catgaatgaa gcagatatag aagatttaaa aaaatacaac tcaataggtg
    25561 caatttgttt acaagccttt gataaagaag gaaaaacttc tatacttgaa tttaatcaaa
    25621 gagtattagg agtgaaactg gaagatttaa aaaagataaa aagaacaata ggtgtcgctt
    25681 caggagatga aaaaatagag gcaataaagg catcattaaa agcgaaattt ataaatagtt
    25741 tagcaattaa tcacagttta gcacttaaat tattagaaga ttgtgactaa tagaaagata
    25801 gataaaagtt aacaggaggg aatgtatatg tcaatatcaa aagaaacatt gcttgaaatg
    25861 tataagagaa tgaatcaggc tagaaaattt gaagagaaag ttagttggtt ttttgcaaga
    25921 ggtatggttc atggaacaac tcacttatct gtaggtcaag aagcgtcaag tgtggcggct
    25981 gtaatggctt tagaaaaagg agatttagta tcattaactc atagaggaca tagtcaattt
    26041 ataggaatgg gaatagacct aaataaaatg atggctgaac ttatgggtaa agaaactgga
    26101 ttttgtaagg gaaaaggagg ctcaatgcat atagcagata ttgagtcagg taacttagga
    26161 gcaaatggag ttgtaggtgg aggtcttaca atagctccag gagctgcact tacacaacag
    26221 tataaaaaaa caggcaaaat agttttatgt agttttggtg atggagcatc aaatgaaggt
    26281 acttttcatg aaggaataaa tttatcttca atatggaaat tgccaataat attttactgt
    26341 gagaataatt tatacggtat gtcaacaagc ataaaacgtc atatgaatat agaaagtatt
    26401 gccactagag cagcttctta tggaatagaa ggaatatcaa tagatggata taacccaata
    26461 gaagtatacg aaacagtaca aaaagctgct gagaagtgta gaagaggaga aggacctgta
    26521 ttaattgaaa gtagaactta tagatggtta ggtcattcaa aatcagatgc aaatgtatat
    26581 agaacaaaag aagaaataga atcatggaaa gcaaaagacc ctattgaatt tttaaaaaat
    26641 tatcttatag aaaataatct atctaatgaa gatgaattag ataagattca agaatttgca
    26701 aagcaatcaa tagaagatgc agtagagttt gctcaaaata gcccaaatcc aaaaatagag
    26761 tctttattag aggatgtata tgcagactaa gaatggtaaa ggaggaaaat aaaaatgagt
    26821 acaagggaat taacatatgc acaagcaata aaggaagcaa tgtcagaaga aatgagaaga
    26881 gatgaaaatg taatatttat gggagaagat ataggaatat atggaggggc atttggtgta
    26941 tcagttggta tgatagatga atttggacca gaaagagtaa gggatactcc tatatcagaa
    27001 gcagctatag caggagcggc agcaggtgca gcagcaactg gtttaagacc tattatggaa
    27061 gtaatgttta tggactttgt aacaatttct atggatgcaa ttgtaaatca agcggcaaaa
    27121 atgagatata tgtttggagg aaaagcacaa gttccaatgg ttgttagatg tccaggtggt
    27181 tctggaactg gttcagcaga gcaacattca caaagtttag aagcttggtt ttgtcatgta
    27241 ccaggagtaa aagtagttgc accttctaca ccagcagatg ctaagggatt gttgaaagca
    27301 gctataagag ataataatcc agtcatattt gttgagaata aattgttata cagaaaaaaa
    27361 ggttttgtgc cagaagatga ttatgtaatt gaaattggaa aggcagatat taaaagagag
    27421 ggtactgatg ttacagtaat tacttatgga agaatgttac aaagtgttga agaagcagca
    27481 gagactctat caaaagaaaa tataaatgtt gaaattatag atttaagaac tttatatcca
    27541 ttagataaag agactatagt aaagagtgta tgtaaaactg ggagagtttt aatttgccat
    27601 gaagcagcta agactggtgg gctaggtgga gaaatatcag ccctgataac agaaagtgaa
    27661 tcatttgatt atttagatgc tccagtaaaa agaatttgtg gaaaagatgt gccaatacca
    27721 tataatccag agttagaaaa agcagttgtc ccaagagttg atgaaataga agaagcaata
    27781 aaatctttaa ttgttagata aggagggata gatatggtgg caaataaaat aaaagccaca
    27841 ccagcagcta gaagtcaggc aagaaaagac aatataaaat tagataggct gattggaagt
    27901 ggagaaaatg gaaggattca tttagtagat gtgttaaatt atttaaaaga taataaagca
    27961 aatactactc ctttagctag aagaatagca gaagatttaa atatagattt agaaactatt
    28021 gtaggtactg gatatagtgg aaagataaga aagtgtgatg tggaaaaatt aactgcaaaa
    28081 gaaactattg tatcaaataa tacatctaaa tatagtgaga aaaaagagct gaaaattgaa
    28141 aatgaaaatt caagcatgtt taacacagta gaaggaatat ttgaaaagcc aaatccaatg
    28201 agagctactg tagcaaaacg aatgtcagaa agttatttta gtgctcctgt atttacattc
    28261 aatatagaag tagatgctac agaattgaag gtacttagag caaagttaat cgacacagta
    28321 aaagaatcaa ctggagtaaa attaactatg acagatttaa tagtaatggc agtatctaaa
    28381 atacttccaa atcatcaagc cttaaattca gcatggacag atgagggtat atttagatat
    28441 aaagatgtaa atatagctat tgcagttggt ttagatgaag gcttatatgt tccggtagta
    28501 aaaaatgcaa acaaaaagtc tttaaaagaa atagcaaaag aaagcaaaga acttgcggaa
    28561 aaagtaaaga cagggaaact tatgccagca gaccaagaag gtaatacatt tacaataagt
    28621 aatgttggaa tgtatggtat aactacattt acacctataa taaatatgcc ttcaagtgca
    28681 atcttagggg taggtgctac acaagataag tttgttccag taaatggaga ggctaaaata
    28741 aaacctataa tgaacttatc attaacatca gaccatagag taatagatgg aacagtagct
    28801 gcaaaattct taaaagattt aaaagaattg ttagaaaatc ctttatcaat gcttgtatag
    28861 gttttgatat ttcgttactg atataaatag tttgaataga ttatattatt ataattgttt
    28921 cagtaaattt aaagctttta tatattaaga attattttta acagtaacta tatgtgaata
    28981 tgatttgctt aattaaaata tatgaaaata aataggagga gagcctatgt cagtagaagt
    29041 aataatgcca aaagcaggag tagccatgga agaaggtact atagtatctt ggctaaagca
    29101 agaaggcgaa gaagtaaaga ttggagaacc tatactagaa ataacaacag ataaagttaa
    29161 tatggagata gagtcagaag gagaaggtac acttgctgta atcatacata aagaggaagg
    29221 tgaagtatta ccagtattta cagtaatagg tgtaatagca gaaaaagggg aaaatcaaga
    29281 ggaagtaaaa gctaaatatt tatctggaaa tgtttcaaaa gaagatatag ttgaagagaa
    29341 tcaaaatata gaagttaaag aagaaaaaat aaacaaaaaa gagtgtaatc atgattatga
    29401 tgtagtggta ataggaggag gacctggggg atatttatca gcattaaaag cagctctttt
    29461 aggtggaaga gttgctttag ttgaagaaaa tatactagga ggtacttgct taaatagagg
    29521 ttgtatccct acaaagactt atataaaaac agcagaaata ttagaagaaa ttgaccaatt
    29581 atcaaagaga ggtgtaaaag taactgtaga taaagaacag gacattaaga aggccataaa
    29641 atataaaaat agagtagtta aaaaacttac agctggtgtt ggcggattat taaaaagtag
    29701 agatgtagat gtgtttaatc ttaaagctag tgttaaagaa gagcataaag taattttatc
    29761 agatggaaaa gttttagata cagaaaatat aataattgct acaggttcca aagtaaggat
    29821 attacctata aaaggaatag aatcaaattt aataataact agtacagaag cattagattt
    29881 ggaaacagtg ccagaagaat tagtaataat tggtggtgga gtgattggtt gtgaatttgc
    29941 agagatattc aattcaagag gttctaaagt aactatagta gaaatggaag atagagtaat
    30001 cccaagaatg gataaagagt taagcgaatc tttaaaatat tctcttagta aaaaaggtat
    30061 aaatgtatta actaaaaaga aagtttctga atttaaagaa gaaggaaata acatattagt
    30121 gtgcattgaa ggtgaagtgc caataaaagc agatttatgt ctatatgcta taggaagaga
    30181 agctaatctt tctggcatag aggacttaga tattaaaata gataaaggtt caatagttgt
    30241 aaatagtaaa atggaaacaa gtataccaag catatatgca gtaggtgatg ttactggagg
    30301 tgtaatgtta gctcatgctg cttttaaaat gggagaggta gcagcttcaa atgctctagg
    30361 tgtgaataaa gaagttgact taggtgcatt acctagttgt gtttatacaa ttccagaagt
    30421 agcatcagtt ggtattacag aagaggatgc tagaaaaaaa tataatgtaa aagttggtaa
    30481 gtttaatttt gctggaaatg gaagagcttt agcttctggt caagaacaag gatatgtgaa
    30541 agtagtagca gatgctaaat atggagaaat tttaggtata catatgtttg gatgtggtgt
    30601 agcagaactt ataaatcatg cagcatcatt taaagcatta gagataccta ctgatgaagc
    30661 aagtgagttg atatttggtc atccatgtac ttcagaagct ttaatggaag ctttggcaga
    30721 tgtaaatgga gaatgtttac acttacctaa aaaataaatc taaacataaa ttattaattt
    30781 aagtctatta ttaatattaa tttatatcat aaaattttaa aacacttact tagccatacc
    30841 ccttattatg caaataattt atttgtataa taaggggtat tttttatgga aaaatataga
    30901 atatagaatc cttgtagttt ttgttgtaca aaaaagatag taatataaaa taacattatc
    30961 attttagaat gatttcaatt gtaattagga a
//
LOCUS       DAMJWO010000047        30832 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.048, whole genome shotgun sequence.
ACCESSION   DAMJWO010000047 DAMJWO010000000
VERSION     DAMJWO010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30832
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.048"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..568)
                     /gene="yqeC"
                     /locus_tag="PC366_002213"
     CDS             complement(<1..568)
                     /gene="yqeC"
                     /locus_tag="PC366_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HDF2577724.1"
                     /translation="MELSNIIEKNEIITVVGAGGKTSFINYFANFYRDKLKVLLTTTT
                     KIYVPNDYDNIIITIDGTVIPSICHGITVCGSYINNENKLVSIDSSILDEIVDQFDLV
                     LIEGDGSKRKKLKGWNAKEPVVYHKTTKTIGILDITSFGMNINEENIHRVEIFKKIAN
                     LDTSSINSSSTVSIENLKNIVLNPNGLFK"
     gene            complement(751..2028)
                     /locus_tag="PC366_002214"
     CDS             complement(751..2028)
                     /locus_tag="PC366_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2577725.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGILNVPMSPAFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIESLKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCVKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFADDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASLNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            complement(2167..4473)
                     /locus_tag="PC366_002215"
     CDS             complement(2167..4473)
                     /locus_tag="PC366_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2577726.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDTVRFIGDE
                     VALVAAEDEKTALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     KNNIVSKEFFEFGDVEAKLKESDFVAESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRIIRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFAIDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTNGKAAEDEILSCELRQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKLLSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGMLKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPIFDKD
                     GRLLTDSFLQYKVPTKKEVGNILVDFAENFDPGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRLRELPMTFEKVYMGMKNNNKQL"
     gene            complement(4466..5260)
                     /locus_tag="PC366_002216"
     CDS             complement(4466..5260)
                     /locus_tag="PC366_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HDF2577727.1"
                     /translation="MVTIKEYSIPQSLEEAYKILISKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDEKNILIGADTSLRSLEIDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGILELSEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSVLNSAMLKENDTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            complement(5366..6724)
                     /locus_tag="PC366_002217"
     CDS             complement(5366..6724)
                     /locus_tag="PC366_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HDF2577728.1"
                     /translation="MKAKSTSKFELDGIPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     ASGLNHKMSTLLIQAALVFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVASKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNPINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLAFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKVVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLEKFPKFIETLLADSSVVSGAMVAIIIQALYMVKFPGNKSDKVEDKNK
                     SL"
     gene            complement(8071..9162)
                     /locus_tag="PC366_002218"
     CDS             complement(8071..9162)
                     /locus_tag="PC366_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577729.1"
                     /translation="MVMQVQEKILELLYTINEDVVSIKNDMSEVKQEMTVMKEDISEV
                     KQEMTVMKEDMSEVKQEINVLKGDMSEVKQEMTVMKEDMSEVKQEINVLKEDMSEVKQ
                     EMIVMKEDMSEVKQEMTVMKEDMSEVKQEMTVMKEDMSEVRQEINIMKEDISEVRQEM
                     TVMKEDMSEVKQEINVLKEDMSEVRQEINIMKEDMSEVRQEMTVMKEDTSEVKQEINV
                     MKKDMSEVRQEITVMKEDVSEVKSEVNFMQNKINNINEDMNGIKDEVSIANEKLYGIE
                     IKIDSLECEDKSMKEIQIEQNNILGSLLHNSEINKATHDNIEHNIAYIKGDTNSIKED
                     IAEIRRDLNLVELATSKNWSDIVKLKSVK"
     gene            complement(9392..10477)
                     /locus_tag="PC366_002219"
     CDS             complement(9392..10477)
                     /locus_tag="PC366_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HDF2577730.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASVGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            complement(10513..11826)
                     /locus_tag="PC366_002220"
     CDS             complement(10513..11826)
                     /locus_tag="PC366_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2577731.1"
                     /translation="MIAIKSKYLISSADEIYTNSAAVVENDIIKDILPNEEVEIKYKN
                     IEEIIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAILSLESCE
                     RISFENGLRCLDENSNLIKWSRENSKLINGIMCTHTSFTCSDRFIKKAKEDAKKLNAP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETVLASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAYVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWKF"
     gene            complement(11827..14118)
                     /locus_tag="PC366_002221"
     CDS             complement(11827..14118)
                     /locus_tag="PC366_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2577732.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDTKNALKVKGVVNIFTYKDVPNYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSKALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGADKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGRTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVRDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKQKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            complement(14108..14902)
                     /locus_tag="PC366_002222"
     CDS             complement(14108..14902)
                     /locus_tag="PC366_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HDF2577733.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKDLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMNLADFLESELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMAKALVVRMYNSIGGECDGK"
     gene            complement(14941..15387)
                     /locus_tag="PC366_002223"
     CDS             complement(14941..15387)
                     /locus_tag="PC366_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HDF2577734.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVDGQHITTLEGVLDEAKKFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            complement(15459..16865)
                     /locus_tag="PC366_002224"
     CDS             complement(15459..16865)
                     /locus_tag="PC366_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2577735.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHNHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTEKD
                     MELTKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTANEEKALKDAQDTAERLC
                     VRGTIKNRMEGHKWNSLY"
     gene            complement(16883..18253)
                     /gene="hydA"
                     /locus_tag="PC366_002225"
     CDS             complement(16883..18253)
                     /gene="hydA"
                     /locus_tag="PC366_002225"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HDF2577736.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDEKIVEIGNNLEINGDKVID
                     ATGKIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKASGNCYCDYGFHMTITCLNKDTFNHMEKLISDGIVSFKMYMAYDGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLDVLIEENIQNGNLEPKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCRESLETVKMAREKNIDMIVETCPQYLLLEDNLYNKN
                     KFEGAKYVMSPPLRKKEDINYLWEGLSSGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISVNKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKVKCKVEDVFLRGNHVVQSCNVKEHPTGQYI
                     KRKITK"
     gene            complement(18386..19573)
                     /locus_tag="PC366_002226"
     CDS             complement(18386..19573)
                     /locus_tag="PC366_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HDF2577737.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNRDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGVNAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIKTIGFGPSKENLAHTIDEYIEQEQLFIGTEGYYGILKSV
                     YGK"
     gene            complement(19700..20914)
                     /gene="dpaL"
                     /locus_tag="PC366_002227"
     CDS             complement(19700..20914)
                     /gene="dpaL"
                     /locus_tag="PC366_002227"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HDF2577738.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAQEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHAAAFVSAPDWVSAKGMRTLGNP
                     LNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRILLISTEGDTDPDKY
                     RSIVWDGEYPSI"
     gene            complement(21277..21948)
                     /locus_tag="PC366_002228"
     CDS             complement(21277..21948)
                     /locus_tag="PC366_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2577739.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            complement(22031..24247)
                     /locus_tag="PC366_002229"
     CDS             complement(22031..24247)
                     /locus_tag="PC366_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2577740.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGSLRFYEHNIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAVKLIKVEYEELPAVFTIQDAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKEIGMDLVDFQNKNAVEPD
                     DVDIIFRGSLGNPRVLDCIEQGKKMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLLTGAHDMGNGVVTMQTMMVAEVLGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKNLIVEEAEKLLETSKEDLYLDNGYVISKL
                     DENVKASLSDVAVYSQSKSLRELTVVEDYSSPAGLTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVNSYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            complement(24250..24720)
                     /locus_tag="PC366_002230"
     CDS             complement(24250..24720)
                     /locus_tag="PC366_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HDF2577741.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLAKNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIKEAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            complement(24782..26176)
                     /locus_tag="PC366_002231"
     CDS             complement(24782..26176)
                     /locus_tag="PC366_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2577742.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKKVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMVELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNVILENGKVTTIESEEQVLLNAQLAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            complement(26249..27610)
                     /locus_tag="PC366_002232"
     CDS             complement(26249..27610)
                     /locus_tag="PC366_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HDF2577743.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGTQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSITSIISSLFAALPTGVFSQNTVIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            complement(27908..29230)
                     /locus_tag="PC366_002233"
     CDS             complement(27908..29230)
                     /locus_tag="PC366_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HDF2577744.1"
                     /translation="MFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVVGGAVGVSPT
                     QITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVGGNYGLASIL
                     GAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMAGGVNSPTYA
                     SMQNWAVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIINFDPIREATW
                     FAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNITDKELSSGVI
                     GSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGFVPKFGALM
                     TTIPYSVLGGATISIFSMITMTGIKLIITEELSSRNITIVGLAIALGMGITSVPAAQE
                     AFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            complement(29586..30626)
                     /locus_tag="PC366_002234"
     CDS             complement(29586..30626)
                     /locus_tag="PC366_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2577745.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFTRIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKILE
                     YFKLNNINIKLLEESDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
BASE COUNT         9302 a         6110 c         3379 g        12041 t
ORIGIN      
        1 ttttaaataa tccatttgga tttaatacta tattttttaa gttttcaata cttactgtag
       61 aactactatt aatactactt gtatctaaat ttgctatttt tttaaatatt tctactctat
      121 gtatattctc ttcattaata ttcattccaa atgatgttat atctaatatc cctatggttt
      181 ttgtagtttt atgatatact actggttctt tagcattcca acctttaagt ttttttctct
      241 ttgagccatc tccctctatt aaaactaaat caaattggtc tacaatttca tccaaaatag
      301 aggaatcaat acttactaat ttattttcat tatttatata actgccacag actgttattc
      361 catgacaaat agatggaata acagttccat ctattgtaat aattatattg tcataatcgt
      421 ttggtacata tattttagtt gttgttgtaa gaagaacttt caatttatct ctataaaaat
      481 ttgcaaaata gtttataaac gaagtttttc ctcctgctcc aactacagtt attatttcat
      541 tcttttctat tatatttgat agttccacac tttcacctct tataaccagt tttctaatct
      601 cttaattatt atagttagac ctttttagta aaagtgattt ttgaaattcc ataaactcga
      661 aagtaaatag attctgttgt aaacaacaag gcggatccaa ttcgccgcta agctgtaagc
      721 ttacgctatc agtttatctt ttaaatataa ttaagatatt cttactctct gtggttgctt
      781 taatatttga ggattattct gtaaattaga taaattaact acttgtgatt tttttagtat
      841 attaagactc gcatttacat ctgcatttat aatgattcca acactggatt tgtactgtcc
      901 acgtgttatt ctttcccctt taaagtcata ttttttaaca ttgtccacat tgatatcagg
      961 tagaaaatca tcagcaaaaa aatcagactt actagtatag ctttcttctt gcctaataaa
     1021 attgatattt tttattttac atagatattc taattttcct tttatctctc caaatgggat
     1081 tcttataaaa tttctatata tttttctctc catattatca cttttttcta acttagcatt
     1141 atatcctaca attaaatttc caatattatt ttttacacaa taatcaatta tataaaaaca
     1201 ggttttattt acatagtctt taacttgatt atttctctta ttccaaactt taaattgttt
     1261 tcttgttatt gcagttatat tcttttttaa ttttaaggat tctattttat cattctgttt
     1321 gtttgcccac tgattcacag attttagcct ttttccatct atgataaaac tatcacctaa
     1381 attggtaaca catgtacata aattttctaa acccaagtct atagctagtg catttttttg
     1441 atttgaaact tcctctgatt tcggtatttc ataacaatac tgaatttcaa agaacctagc
     1501 tttatgttta ggtattattc ttatttcttt aatttttttc tctagtatat tttgtggaac
     1561 ttttatactt actttcccat atagtttttt aaatgctgga gacataggta catttaaaat
     1621 cccatcttct ttgattctta tttgacctat tattatgcta aaaaatcctt ctttatctaa
     1681 atatttaggt gattttatcc ctctaaagtc atatttccct tctttggcta atttaattaa
     1741 cccaaaaaat gacctaaacg aactgtctac ttcttttaat atttgttgcg ctatattact
     1801 attgagaagc ttatagttct cattttcttt gcatacatga taattagctt catagttaag
     1861 atgttctcct tgattgaaat aatgctgtct tacattatat gtaccaacat tatataagtt
     1921 cttagctaag aagcacatct ctcgtagagc ttgatattct tttttagtta agttttttaa
     1981 ttgttgtctc tgagttccat agtgtatatt ttttattctg tttgacatga actcacctcc
     2041 tttagaatat actctactag acattatata cggtattttt acaaaacacc atatataatg
     2101 tccatttaat tactttattt tacaaaataa tttaaattta cttgctttta tacaccttat
     2161 tatttattat aattgtttat tattattttt catacccata taaacttttt caaaagtcat
     2221 aggaagctct cttaaacgaa ctcctgtagc attaaatatt gcatttgcta tagctggcgc
     2281 tggtgtatgt ataactattt ctcctaatga tttagcacca taaggacctc ctgggtcgaa
     2341 attctcagca aaatctacca atatatttcc aacttctttt tttgtaggaa ctttatactg
     2401 taggaaacta tctgttaata atctcccatc tttatcaaat atagggtctt catacattgc
     2461 aaaccctata cccatcatca caccaccttc tacttgtatt ctagctaaag ttggatttat
     2521 aactgttcca caatcaggta cacatgcaaa atttatgacc ttatattcgc ctgtattttt
     2581 atctaattct atctctgcaa atcctgctat aaatggtttt atttttttca acatgccaaa
     2641 agattctgtt gcttccaaaa ctactggtac atcatcacta gcaaatccta ttcctccaac
     2701 agattctcta cccaattcct ctaatagaac aaacttgcta ttatcgtttt taacaaaaac
     2761 cctgtctttt cccaactcta aatcttcttt tttaaatcct agctttgact ctgcaactga
     2821 aagtaatata tcttttaatt tatttgctgt ctttattgtt gcatttcctg taaccgttgt
     2881 tgtacaagaa gcaaatgctc ctgtatcata gggacataaa tctgaatcac ctgtataaat
     2941 agaaattcta tctacagtag tatttaaagc ttccgcagca atttgagctt gaattgtatc
     3001 agccccttga cctaagtcag caagaccaga taatagttta tatgtgccat cttcatccat
     3061 tcttatagtg actgttgcca tatctacacg cggtatacca gaaccatgat ttgctactgc
     3121 catacctact gctcttactt tgttgtttcc tatatcttta catggatatt tatcatccca
     3181 attgattaat ttcttgccct tttctataca ttgtctcagc tcacaactta atatttcgtc
     3241 ttcagctgct tttccattgg tatacctatc tattatattt ttaattctaa attcaagtgg
     3301 gtccattcca atcttatgtg ccaattcatc aatagcacta tctattgcaa atattccctg
     3361 tgtagcacca taccctctaa gtgctcctgc tggtaaccta ttagtatata ctgttctagc
     3421 attaaatcta acagcatcaa tatcattata tattggtaag gtattgtgtc cagattcgga
     3481 agaaacagag acaccattcc caccataagc acctgtattg tttaatgact ttagctctat
     3541 tgcttttaaa tttccttctt tatctgcacc aactttaaca tcaaaaaaca tttcatgtct
     3601 actattagaa cctacaaaag tttcacttct tgtaaataca aattttgctg gtctaccagt
     3661 tttcatagta acaaatgcag taaatatatc tgttgctgct atattctttc ctccaaatcc
     3721 accacctatt ctaggtttaa ttactcttat ttttgaagat ggtataccca atacttttct
     3781 aattattctc tttacattgt gtggtgattg taatgatgaa actacaacaa ttctatcatt
     3841 tatatcttta tatgaatatg acctatgagt ttccatcatg caatgcgatt gactttgggt
     3901 tttgtatgaa gattcagcca caaaatcact ttctttaagc ttagcttcaa catctccaaa
     3961 ttcaaaaaat tcttttgata ctatattatt ttttgcatcc aatccaaaag ggtatggctc
     4021 tactatgtct ttttctggat gtataacaac ttcatttcct tctgcttctc ttgcatcaaa
     4081 cacaggcttt aaaacctcat aatctacctt tatcattttt aaggctttaa gtgctgtttt
     4141 ctcatcttca gcagccacta aagctacttc atctccaata aatctaactg tatcttcaag
     4201 taaaactcta tcataaggtg atgcttctgg ttctgtttga cctggcacac aatatctgac
     4261 ctgtggtaca tctttatacg tataaatacc cacaacccct ggaatttttt cggcttttga
     4321 tgtatctata ttctttatct tagcatgagc atgtggactt ctaagtagtt ttaatgtcaa
     4381 aacatcttta tgcataatga ggtcttcagt atatagaggt tttcctgtga caattgctgt
     4441 actatctatc tttcttatcc ccttattaat cattatacat tccctcctca atagcattat
     4501 acatcctttt aactaatgca cttgccatat cctttctgta ctctttacta gctctcatat
     4561 tacttccata agtaagttcc ttactagcaa caatagatgc cttatctata tctttttctt
     4621 tatttaatat attactcgct tcaagtgcta atctagcttt ttgaggtctt gccccaattg
     4681 ctattttgta agtatcattt tcttttagca ttgctgaatt taatacagaa aaatctcctg
     4741 tgcattttct tattgagtca aaaacagcta tcgcatcttt ttttggtagt attacttcga
     4801 ccaatatatc cctacttaat tcactatcca aaaactcact taactctagt attcctttat
     4861 tgtataatct caccttcgct ccaacaacca aaagcgctgg tattaagtca gaaaagccat
     4921 actttgaaaa tacacttgca ccaattctag ccccttgtct aaattgaaca ccaactatat
     4981 tagaaacagc gcttgaaagt attccactac agtaattttt tatagtttta tcaatttcta
     5041 aacttctaag tgaagtatct gcacctatca aaatattttt ttcatcctct tttatataat
     5101 ttagatttat atcttttaaa tctatcgctg ttcctatatt tttattactt aattttataa
     5161 atccacatcc acctaaaata acattatttt ttttagaaat taaaatttta tatgcttctt
     5221 ctaaactctg tggaattgaa tattccttta tagtaaccat cttatccccc atcattaact
     5281 tattaaaaca caaaagtttt taataaatct tttatttata tttataattg tagtatattt
     5341 aattcacata tattaaacct ttacattata aacttttatt tttatcctca accttatcac
     5401 ttttatttcc aggaaatttt accatatata aagcttgaat tattatggct accattgctc
     5461 ctgaaactac acttgaatct gcaagtaatg tctctataaa ttttggaaat ttttcaagaa
     5521 cttgaggagc taccatgaat ccaataccag aagccataga aagacctaat atcatgctat
     5581 tttcttgatt aaatccatcc atactaacaa gtcttaaacc agatgttgta agagttgaaa
     5641 atataacgag tgttgctcct ccaaccacac agggaggaat tgttcttatt aaattagcta
     5701 ataaaggcga tattcctgcc aaaaataatc caattcctcc aatagctagt acaaatttac
     5761 ttacaacctt tgtattggaa acgattgcag aattttgtcc aaacatcccc attggagttg
     5821 cagaaaataa tgcacctatt gtagagagta ctccatttcc taaaacagca gaagaaagtt
     5881 cttcatctgt tacttgtcta ttaagccctc ctaccgcaga aagtgtacaa gcacccatta
     5941 tatcagctat ctcaactaaa tatattattg aaaacattac aacaacttca agtcttatat
     6001 ctagcccaaa agcaagtggt tttggaagcg caaccaaagt aaactcctga attgaagaaa
     6061 aatttactat acccaaaatt aatgataaaa tgtatccaaa aattatgcta actaatattg
     6121 atgcatcttt aaataatcct tttccatact tatttaatcc taatatcata agagatacag
     6181 atattccaac tataaaatta attggattcc caaaagtctc attgcccata cccccagcta
     6241 agttttttat agctattgga aaaagtccaa gacccataca tgcaactatt gttcctgata
     6301 cagctggagt aaatataaat cgtatttttt taagaccaaa accaattata attattacta
     6361 taccagctat tatttgagag ccaaataata ctggtagtcc atacttactt gcaacagata
     6421 ccccagctcc tataaacata gctgtagctc ccattataac tggtattcct cctcctaatt
     6481 taaaaccttt aaacaaaggt attggatata attgtaataa agttgataat cctgcaaaaa
     6541 ctaatgcggc ttgaatcaat aatgttgaca tcttatgatt aagtccagat gcatttgcaa
     6601 tcaatatcgc tggtaaacaa ctacctatta ccattgccat taagtgttgt aaccctaaag
     6661 gtattgcttc ctttagtggt ggtattccgt ctaattcaaa ttttgatgta ctttttgctt
     6721 tcataataaa aactcccgtt acataaaact tattgaatta tataaatact taaaaatcta
     6781 atatattaaa ttaatgatgt tcataaatat caactatact ccaacatata tttaagtttt
     6841 tagtcttaaa aaacagatgc aataaattta attattaaca aatacacgta ttctttaatt
     6901 ttgtatacat tatataccat gctttacaaa tataagagta ttatagctat gaatttttaa
     6961 ttttttatag taaatttaat tcaatttaaa tctttcaatc ttaatcatta taagttataa
     7021 gttttcataa gtatttacat gtttcaagtt ttaaacattt acctataaac gctactttat
     7081 agatgtcact tcaaatctag tgacctcata ctttcatatg agcgtagact atttcttcat
     7141 cttcagcatt acctgctaag agcaacccgt ttccactatc aatcgcttat agtgtactct
     7201 ctctcgagat agtcgtttga ccttcctatt tctaggcttg gcgaccaaat gtccattttt
     7261 aagtacttag gctctcacca tataccatcc tcactattgt ttctggtttt caccacattc
     7321 ataaaagttt ctttctatct tttattgtag ttgcaaggct ttaggattta ctggttttaa
     7381 agttgtgtcc tacatagatt tctctatgta cggggccaaa agtacaattt atttaacata
     7441 ctttgcttta ccccctgtaa ataatattat ttactctttc actgtttttg ttattaaatt
     7501 aattaaatat caattaatct aagcataaaa taattattta atttaaactc aaaatattta
     7561 tgaatatttt ataatataat tctcataaga cagaaaaact taataagcta tgtatctcag
     7621 ttgtaccaat gtactctcct ttactatatt tgtatctgca acataaaata tacaagtttc
     7681 tatctattta tagatatata tatctataag caaaatagta atattatttt tatagtaaaa
     7741 attttattca tattactatt tataattttt atagagcaat tttagtgcca atatttgcat
     7801 acatttgtat agtataaaat ttttatgttc tcattgataa aattttactt atttcaagcg
     7861 ttttattcga ttttatcatc taaattttag gttttatttt tataaattaa ttgtatttac
     7921 ataaaaaaaa agacctaaaa acaaattttt aacggtcttt tctcaatttt ttattttcat
     7981 ttctaaaatt tataataaat agtaagaaca ctataaattc ttttatataa aattcttagt
     8041 ttgtggatga taaattagtg aattaaaata ctactttact gattttagtt tgacaatatc
     8101 actccaattt ttactagtgg ctaactctac taaatttaag tctcttctta tttcagctat
     8161 atcctctttt atagaattag tgtcaccttt tatatatgct atgttatgtt ctatattatc
     8221 atgagtagct ttatttattt cagaattatg taataaactt cctaaaatat tattctgttc
     8281 tatctgtatc tctttcattg atttatcttc acattctaga ctatcaatct taatttcaat
     8341 tccatataat ttttcatttg ctatggatac ctcgtcctta attccattca tatcttcatt
     8401 aatgttattt attttatttt gcataaagtt tacttctgat ttaacttcgg aaacatcttc
     8461 tttcattaca gttatttctt gtcttacttc tgacatgtct tttttcatta catttatctc
     8521 ttgttttacc tctgatgtat cttctttcat tacagtcatt tcttgtctta cttcagacat
     8581 atcttctttc attatattta tctcttgtct tacttcggac atatcttctt ttaatacatt
     8641 tatctcctgt tttacttccg acatatcttc tttcattaca gtcatttctt gtcttacttc
     8701 ggatatatcc tctttcatta tatttatctc ttgtcttacc tctgacatat cttctttcat
     8761 tacagtcatt tcctgtttta cttccgacat atcttctttc attacagtca tttcctgttt
     8821 tacttccgac atatcttctt tcattacaat catttcctgt tttacttccg acatatcttc
     8881 ttttaataca tttatttcct gttttacttc cgacatatct tctttcatta cagtcatttc
     8941 ttgttttact tccgacatat ctccttttaa tacatttatc tcctgtttta cttccgacat
     9001 atcttctttc attacagtca tttcttgttt tacttctgat atatcttctt tcattacagt
     9061 catttcttgt tttacttccg acatatcatt ttttatgcta actacatctt catttatagt
     9121 atataataac tctaaaatct tctcttgcac ttgcatcacc atccctatta attattataa
     9181 cattttacac aaatgctata caatgttaac atatatatca gaattattaa aattttaatt
     9241 aaacaaaatt gattcacttt attacttcaa aactaattaa tatctaaaat aactacaaat
     9301 aaacaaaaat aaggtcaaca acaaaaaagg cttatctctt tgagatagcc tttcttattt
     9361 ttatttaaaa ctttgttttt tataaaataa tctatacatt cagctctgaa catgaaattt
     9421 ttcttccaag tgcttttggt ttacaaactg atatacaaag tccacaatat ctacactctt
     9481 cttcattcaa ttccatctta tcattcaatt ttctcgcttg atatgcacaa actctctcgc
     9541 acatcttaca tttagtacat ttttcttcat cataagtaaa ctcaaagcta agtctttcat
     9601 taacatctcc catatgatta tgtactatac cacaagcatt ttctatagta ttatatccta
     9661 atctattaag attagatttt aaatcatcat gtattttaga tattacttgt gcgcctttta
     9721 aaattactac tgaacatata ccaacaaagt cagcacctgc cataatcatt tctaaggcat
     9781 catctccact tacacatcca cctaagccaa ttattggtat attaacttgt ttttttattt
     9841 catatattct ctgtaaagtt attggcttaa tagtttctcc acttaaatat cctattccat
     9901 ttccacctaa taaaggttgc cctgtttcta tgtctattct aaatgctggt cctacagagt
     9961 cacaagcagt tattgcatct gctcctgctt cttctaattt tttagcaaaa tcgcctatct
    10021 catctatcat aggaggaagt ttaactatta caggtatatt tactctttcc tttgcatctt
    10081 taagcattgg tatcaaatct ctatagtcat aagatactaa ttcaataaag tcagctcctg
    10141 catttgcaac tttctctact aattcgctac tttcttcaat tgtatgacct actgaagcta
    10201 tacagacagt cccatctctt ttcatttgtg gtatttcaaa atctatccat tgctctggct
    10261 caaaatctgt ccatttttca ttatttaaaa gagcattagc tgtatttcta accatatgtg
    10321 gtgctggatt tatagctctt tcttttctta tagtcttagt cacaactgcc cctgctcctg
    10381 catcacttaa tatcttgcat ccagctgcac tatatgttaa tggtcctgaa cctattataa
    10441 gtggtgattt taattcttta cctaaaaaat tatacattat ctgcttcccc ttttcatata
    10501 tatttacatt cgttaaaatt tccaaaattc acaagcaact tctttcattt ctttaacaat
    10561 agctttttta tctaaatcaa ctaactgttt ttcttttaaa atatgtctac catctatgta
    10621 tacatttgat ataaattctt ttttaccctg aactactatc tggtcaaata tattatcaag
    10681 agtcacagga gttttaaatt catcttccat aactattata tcagccttat taccaactgc
    10741 tattttacca gaattttgaa gtcctaatac ataagcacca tgctctgttg ccatcctaaa
    10801 tactaaattt gctggcatta ctgatgcatc ttcttcaact gatttatgca ttaaaaatgc
    10861 acctctcata acttcaaaaa aatcatttat atatccatca gtacccagtg ccacttttat
    10921 gcctttttta atcatttttg gtactggaga aaaacctcca cctacttcac agttgctaag
    10981 aggcatatga accactttta cacctttttc ttttaatata tctatttctt catcatttac
    11041 ttttacacac tgagatgcta atacagtttc atccaatata tctaaatcat tatagtagtc
    11101 aactgctttt ttgccaaaat gtttttcagc atagtttggc tcatatatac tctcacataa
    11161 atgaaattgc attggtgcat ttaatttttt tgcatcttct ttagctttct taataaatct
    11221 atcagaacat gtgaagcttg tatgtgtaca cattattcca tttattaatt tactattttc
    11281 tctactccac tttattaaat tagaattttc atctaaacat ctaagtccat tttcaaagct
    11341 tattctttca caactttcta aggataaaat cgctttcatg cctatttctt ctagtatttt
    11401 tccttgctca attaaagttc cttcttctgt atttggagct tctagggtat cacaaaaagc
    11461 taccacacca gattctataa gttctattgc tgatgcttta gttgttgcct tcacttcttt
    11521 caatccaatt ctattttcta taaatggcca ccaatagtca tttaaaaaac cttcaaagtc
    11581 agtaaaatgt acatttgccg gtattcccct agaaagaact ccatattgat gcatatgacc
    11641 attgacgaat cctggcatta ttatagcatc tgatttatct attatttctt caatattttt
    11701 atattttatt tcaacttctt catttggcaa tatatctttt ataatgtcat tttctactac
    11761 agcagcagaa tttgtatata tttcatcagc agaagatatt aagtatttac ttttaatagc
    11821 aatcatttat ttacctccct gatttaattt tttcatggcc atataaactt tctcagaagt
    11881 tataggaagt tctcttatac gaactcctgt ggcattgtat attgcatttg ctattgctgg
    11941 tgcaggtgta tgaataacta tttctcctaa agatttagct ccatatggac ctgttggctc
    12001 ataattatct acaaaatcaa caattatgtt tcctatatct ttttttgttg gaactttgta
    12061 ttgtaataga ttagaagttt gaagctttcc atcagaacca tgtctagggt cttcatacat
    12121 tgcaagccct ataccttgag ttacaccacc ttcaacttgt attctagcaa gtgcaggatt
    12181 cataactgta ccacaatctg tagaacaagc ataatttatt actttaaact cccctgttgt
    12241 tttatctaac tctatttcag caaatcctgc taagaatggt ttagcactct cttgtatacc
    12301 ataagattca gatgaatata aaacttcttg atttccacca ccaacagatt cttttcctaa
    12361 ttcacttaac aaaacaaact tctctacatc ttcactataa caaactctgt cttcatatag
    12421 tattaaatca tctattggta aatcgagttt cttctgtgct acttttaata tcttttgttt
    12481 taaactttca gcagatttta ttgtagcatt tccagttaca taagtagtac aagaagcgta
    12541 tgcaccagta tcatatggac acatatctgt atctcctgta taaacggaaa ttctatcaat
    12601 agatgtattc aatgcttttg cagctatttg tgcaagtatt gtgtcagaac cagttcctaa
    12661 gtctgaagac ccagaaaaca acttataagt tccatcttca tccatcctca tatttactat
    12721 tgccatgtct atgttggcta taccagaacc atgagttccc acagacattc caacagccct
    12781 caccttattg tttccaatat ccctaacagg gtacttttca tcccatccaa taagtttttt
    12841 acctctaatt atacattcat caagtgcaca acttcttatt ggaaaattca ttattccgcc
    12901 ttcagtttgt ttttttataa tattctttaa ctttatttct gttgggtcca tattaagttt
    12961 atgcgctaat tcatcaattg cacaatcaag tgcaaatgta ccttgtgttg ctccatatcc
    13021 tcttaatgct cctcctggaa ctaaattagt atatacagtt ctcccatcaa attttattgc
    13081 aggtacatta ttatatgttg gaagtacatt atgacctgat tcagagcaaa ctgaaggtcc
    13141 attatcacca taagcgcctg tattattcaa tgctttcata tctatagctt ttatgtttcc
    13201 ttctttatct gccccaattt ttatatcaaa aaacatctga tgtctagtat tagtcattgc
    13261 aaaagtttct tctctagtat aaattagttt tgctggtctt tttgtcatcc aagttacaaa
    13321 tgatgcatat atctctgtta cagctatgtt ttttccacca aaacctccac ctattcttgg
    13381 ttttattact ctaacttttg aaagaggtat tcccagtgct ttagaaacct gtcttctcat
    13441 atgataagct gattggtttg cagaagttac tactaatctg ccattcgtat ctatatacgt
    13501 ataagctcta tgagtttcca tcatacaatg ggcttgtgat tgagtcatat aagaatgttc
    13561 tactattaca tcactttctt taaactcttt ttctacatcc cctttaccca ttttttctct
    13621 cgatacaata ttttttgtag catccaatcc aaaatcaaat ggacaaaaca aatcatcttc
    13681 ttcatggatt aaaattttat ttccttccga ttctcttgca tccaatatag gagtcattac
    13741 ttcatattca acttttataa gtttcatagc tttaatagca gccctttcat cttcagcggc
    13801 tattatagca acttcatctc ctacatatct aactacgtct tcaagtatta attggtcatg
    13861 aggtgatgct tctggatatg actctccaac cattgaatat ctataatttg gaacatcttt
    13921 gtaagtgaat atgtttacta caccttttac ctttaatgca ttttttgtat ctatgttttt
    13981 tatcttcgca aaagcatgcg gacttctaag aagcttaatt gttaaaacat ctttatgaaa
    14041 aattaaatct tctgtatata ttggttttcc agtaacaatg gcttcactat ctatttttct
    14101 tacctcttta tttaccatca cactcacctc caatactatt atacattctc actactaagg
    14161 cttttgccat atcttttctg tattctttac ttcctcttat attacttcca aatgaaagtt
    14221 cttcacttga tacttcacca gctttttcta tatcattttc taaacttaat atttcacttg
    14281 ctttataggc aatttttgct cttcttggtc tagcgcctat cgcaatttta taaatacttc
    14341 cttcttttaa cattgctcca tttaatactg caaaatcacc tgtacatttt cttatagaat
    14401 caaatacacc tatagcatct tttttaggta atataacttc tattaatata tctttttcaa
    14461 gctcactttc taaaaaatca gctaagttca taaccccttt tttatataac ttaacctttg
    14521 catctaccac tagtaatgaa ggtattaaat ctgaaaatcc atacttagca aatacgctag
    14581 ctcctactct ggctccactt ctaaattgaa ctcctactat attagaaaca gcgtttgaaa
    14641 ttaccccatt acagtaattt ttaataacct tatttaattc taaagttctt aaacttgtgt
    14701 ctgctccaat taatatgcta tcatcagttt catttatata atctaaagct aagtctttta
    14761 aatctattgc tgagccaata tttttactac ctagttttaa aaatccacat cctccaagta
    14821 ttatgttgtt ttttcttgat attagcagtt cataagcttc atctaaactt tttggaacta
    14881 catattcctt tatagttatc atactctctc cccatatcaa cttaattttc acttaaaagt
    14941 ctaagtgttt aaatatttat gtattgctct taattgacct ttatatcctg tacatctaca
    15001 aaggttacca tttacataat ctataacttc ttcttctgtt ggattttgaa gctctctttt
    15061 cattgccaaa accatcatta taaatccagg agcacaaaat ccacactggt cagccccttc
    15121 gtctgcaaga aaatctccaa acttctttgc ttcatccaag accccctcaa gtgttgtaat
    15181 atgctgacca tctactctag cagtaagata attacatgaa agcacggcct tgtcatttac
    15241 catcactgta cataacccac atgagcctgt atcacaccct tttttaacac ttacatatcc
    15301 attttctctt aatgtatctg ctaaaaaatc atctggtctt atacttaatt ctttttcttt
    15361 attatttatg gtacatttga taatcaaata aatcacctca aaactcatat ttttaagcta
    15421 aagttttact atacttttct atgaataaat tacatttatt aataaaggct attccattta
    15481 tgaccttcca ttctattttt tatagttcct cttacacaaa gtctctcagc tgtatcttga
    15541 gcatctttta atgctttctc ttcattagct gtcaatattt ttgaatcttc cattattata
    15601 tttccatcta ctataacact ctctatattt ttcatactag aagaatatac taatgtagat
    15661 accggattat gcataggtat cgcttttggt gaaagcattg gattaaatat tagtaagtct
    15721 gcttttttac ctatctccaa tgaacctatc tcatcttcca ttccaatagc tcttgctcca
    15781 tctatagttg ccaactcaag aactttttct gccgacattg ctaatgggtc acacttatta
    15841 actttatgtt gaagtgctgt taatttcata agttcaagca tatcttgaga gttattacta
    15901 gcggctccat ctactcctaa actaactgtt attccttttt taagcatttc tggcactggt
    15961 gcaacacctg aagataagta catattactt gctgtattat gagacacttt catatcgtat
    16021 tttttagtaa gttccatatc tttttcagtt agatacacac aatgtaccat aagcacattt
    16081 ggtccaagta ttcctaattt ttctaaaaca tctatgtcat attgcccatg caattctttt
    16141 gctgcttctc tatcaaaagg agtctctgat atatgtactg taaataaagc atcatcatat
    16201 tcttttacca ctctccatag catttcaagc atttcttgag aatttgacca tattgctgca
    16261 ggagctactc ctattttgat tcttccattt tctgtattat ggtgtttttc aaacaatctt
    16321 cttacatctt tttcaaccgt ttctacatct tgcattattc caggatgaac tccaaattga
    16381 gctcctgtat tcatacatcc tcttccaagt attcctctta ttcctaattc tttataagca
    16441 tctattattc catcacaaag acctggctta ctatgaggat acatgtagtc aaccatggtc
    16501 gttataccac ttctaagtcc ttcaatacat ccaagcattg cagcatcata agtatctttt
    16561 ggctctaaat agttagctgc tggaaatgtc atagtttcta accagtcttt aagtaccata
    16621 tcatctccca atccttttaa taaagtttgg aataaatgat tatgtgtatt tataaaacct
    16681 gggaataaaa ctttaccttt agcatctata atttttttaa catcagtata tttactttct
    16741 atctctttag aatttccaat atcagcaatc ttgttatctt ttactactaa tgccccatca
    16801 aaaataactt ctctctcttt attcacagtt actattatgg cattcttaat aagtatatcc
    16861 atcattctta tttccccccg cattatttag taatttttct tttaatatat tgacctgttg
    16921 gatgttcttt aacattacaa ctttgtacta catgatttcc tctcaaaaat acatcttcaa
    16981 ctttacattt aaccttaaat ccttcatatg gagtataatc tacattttgt ttttgagttt
    17041 tataactaat tgtttcttct ttattgatat ttaaaatgac tatatctgca tcacttccta
    17101 cagctatctc acctttttta ggatacattc caaatatttt tgcagcattc gtagaagtaa
    17161 cttccacaaa cttatttaca cttattctat tttctaagac cccatatgta tataaaagtg
    17221 ctaacctatg ttcaacacca ggtgctccat ttggtatctt actaaaatca tcaattccca
    17281 agtctttttg ccccttaaaa ttaaatgaac agtggtctgt gccaactgtt tgaatatctc
    17341 cactagacaa tccttcccaa aggtaattta tgtcttcttt ttttcttaaa ggaggagaca
    17401 ttacatactt agcaccctca aatttattct tattatataa attgtcttct aataatagat
    17461 actgtgggca tgtttctact atcatatcta tatttttttc tctagccatt tttacagttt
    17521 caagtgactc cctacaactt aagtggacta cataggattt tgaattagat aatttagtta
    17581 tatcagcaag tcttgaaaca gactctttct caactatgtt aggtcttgta agtggatgat
    17641 attttggctc taaattacca ttttgtatat tttcttctat caatacatct agtaaatccc
    17701 cattttcaca atgaaatcca actatacaac ctaaatccct tgctttcttt aaaaccctgt
    17761 atattgttcc atcatctact ttcatgccat catatgccat atacatctta aaagatacta
    17821 tcccatccga aataagtttt tccatatgat taaatgtatc tttatttaaa catgtaattg
    17881 tcatatgaaa accataatca caataacaat ttccacttgc ttttttatga tatgcttcta
    17941 caccttgcag taggttttcc ccctcattgg cttctgcaaa atctagtatt gtagtagttc
    18001 ctccagctat agctgctctt gttcctgttt caaaattatc tgcagttgta atagaacctg
    18061 cattcatatc aaaatgagta tgtgtgtcta ttccaccagg aattacaatt ttacctgtag
    18121 catcaataac cttatcacca tttatttcta agttatttcc tatttcaact atcttttcat
    18181 cttctatcct taaatcactt atataagtct tatcagaggt aattatagtt ccacctctta
    18241 gtattgttcc catatatacc tcctaacttt taagctttaa agtattttct aagtatcgta
    18301 aaactttatt taaaattgta ttttctaaag gtgctatatt cagcacctct agactatatt
    18361 taaataattt attgtgaact aaatattatt ttccgtatac agattttaat attccatagt
    18421 aaccttctgt tcctataaat aactgttctt gctctatata ctcatctatt gtgtgagcaa
    18481 gattttcctt agaaggacca aatcctatag tttttattcc agcttcacct gcatagtgac
    18541 ttccattcgt acagaatgag tattgagtta tttctgaatc tattccagct tcttttaatc
    18601 ccttatatgc tgcttgaaca aattcatctt cttcgtcata taaccaacct gggaagaatc
    18661 tttcactttc tatagtattt cctgtatagc aatcagcttt ttcaaccgca taagaaactt
    18721 tcgcatttaa ttctgggtct tctttcatca tttcatctaa taaagcttgt attggagcta
    18781 atacgccttc tcttgtttct ccaactaata atcttctatc aaaagtagct ttgcaataat
    18841 ctggcactac tgatgcccct ggatatggag aagattttat atctgttaaa actaatattc
    18901 catcacctaa aactggatga gttggaggta ctaattgttg tatcttttgg attacattag
    18961 ccattttata aactgcattt acaccttttt ctggattagc agagtgagct ggtttaccaa
    19021 aagtttctac tactatttct cctctacctc tctgaccaat ctttaagttt aactctgaag
    19081 actcacctat tacaacatag tcaggttgaa cagccttact tatctctcta gccgaaacac
    19141 cttcaaatat ttcttcatga acaacacctg ctacatatag ttctccagca aaatctcgat
    19201 tagtgtcttt agcaaaatac gctacagcag acatcattgc agtatattga cctttcatgt
    19261 cagaagttcc tctaccatat atctttccat caactatttt tccttcaaaa ggaggaacac
    19321 tccatttact tgcatctgga actggaactg tatctatatg tccatcaaat aatattttct
    19381 tacctggctt gttacctttt atacatccta ctatatttcc atatctatct cttgaccaac
    19441 tatcaaaacc taatttttca aaagactctt ctattgcttt tacaacacct tcttcatttc
    19501 cagaagaact aggattttga attaattttt ggcatatttc agttacttct tgttttcttt
    19561 gttcgtttaa catttcatta tccccctaga ttttttataa tgtatgtatt ttatatactt
    19621 atatattttc taaattttag aacttatata tcttctaaat atgtaaacca atatctaata
    19681 attgcatttt agtaattcct tatatacttg gatattctcc atcccaaact atacttctat
    19741 atttgtcagg gtcagtatct ccttctgtgc ttattaaaag tattcttgaa ttttcatcta
    19801 attttaaatc ttttcttaaa tctgctaaat cttctctttc catagctgct actaaaagac
    19861 cagttgtaac tgctccagat tctccagaaa ttaccttttc atcaccattt aaaggattac
    19921 ctaatgttct cataccttta gcagaaaccc agtctggtgc tgaaacaaat gctgcagcat
    19981 gattttttaa tacttcaaat cctatagtat ttggttctcc acaagcaaga ccagccatta
    20041 tagttggcat atctcctcca acaaatcttg gttttccatc tcctgcttct gctgatttat
    20101 agtagcaatc agcttcatca gcttctacta ctactgttat tgggcattca tcgtatattg
    20161 aagcaacata tccttgaact gctccagcaa gtgaaccaac ccctgcttgc acaaatacat
    20221 gtgttggtct atctactcca tattctttta attgctctat cgcttcttga gccatagttc
    20281 catatccttg cattatccat gctggaattt cttcatatcc atcccatgct gtatcttgaa
    20341 ccattactcc atgatcatca gcttctgcat aatcattagc taatcttact gcatcatcat
    20401 agtttaagtc tgttatacta gcatctgctc cttctccttt aattttattt aatctaaact
    20461 cagaagaacc ttttggcatt aatacaacag atttttgacc taatttatta gctgtccaag
    20521 caactcctct accgtgattt ccatctgtag ctgtaaagaa agttatttct cctaattttt
    20581 cttttatttc tttcgaagtt aatttgtcat accctaactc agatatatct gtatctaatc
    20641 tttgagctaa gtatctaccc atagaataag aaccacctaa tactttaaat gcatttaatc
    20701 caaatctata agattcatct tttacatata ctcctgcaac acctaatttt tttgctaaac
    20761 cttctaggtt tgctaatgga gtttctttat attgaggaaa gcttttgtga aaatttctaa
    20821 ccttagttat ttcttcttca tttaaaaatt tgatacaatt ttccttatca ccctttggca
    20881 aattatttac tttccattta atttctttta acatctaaaa tacctccaaa ttattgttaa
    20941 atttttatac tttaatatat aagcaattaa catgccaaca ctaaatatat actagatatt
    21001 tttctatgac tctttagtat agaaattgca atgcttttat tattctttct tttctatctt
    21061 tagttcatac aatgtatgta gaatttaata actaaaaaac cttttctatc ttctcacttt
    21121 ttaattctca tttttaaaat ttaaaaataa atctcaaaac actttgtttc tatatttttt
    21181 aatataaaat ttataaaatc taaattaaaa cataaaatag tgatgcaata atctattaca
    21241 tcactatttg tatatattta ataatataat aaatctttag tggtctctaa gaggtgattt
    21301 ttcatctttt ttaacatcta attcttcttt tacgacattc catttttcaa gaccaaactt
    21361 agaaaccata actgcctctg cagcaccttt tccaagtctt tttactgtgt ccatacctgt
    21421 ctcatcctct tgggcacctt ttgcttttcc atctttactc catattgtac cacctatata
    21481 gcatccacct aaacctccag atactaacat ttcatgcatt aggaagaaat ttattatagg
    21541 aagttttgtc aattcttggc caccatatct agttccacca gtagttatag ctgcaccaac
    21601 cttattttga agttttcctg gatgaactaa atacattgga cgaagtctat taaatactgc
    21661 tgtaagttga gcagttatat tcatatcata aactggagaa cctactataa ttccatctgc
    21721 ctccaatatt ttttgctcta attcttggat atcatctttt ataatacaca tagtttcttt
    21781 tcttatacat gcatcacaat gtacacaagg acttattttt ttccctctaa ctgaccaata
    21841 ctcagtttct ataccaggta tagtttctgc ttctttcaaa gcttctaaca ctgcatattc
    21901 tgttgctcct ttacgtggac ttccacaaat acctaatatc tttgccataa taatatctcc
    21961 tcaccaaata aatctatttt tattatctat ttacaaatac aataaattgt tgtttgtgct
    22021 ttaatttcta ctattttaat tttattggca atgaatgtat ttctacatca gttgcattat
    22081 atactgcatt tgcaacagct ggcgcaactg gtacaacagc acattctcca atactcttac
    22141 caccaaaagg tccagctttt tcataactat ttacaaatgc aacttgacat tttggcatat
    22201 ctacagttct aaataattta tatgttttaa aatcagtagc tttaggtcta ccttgttcat
    22261 caaatgccaa ttcttcactc aatgcgtatc ctagacccat atgaatccca ccttctaatt
    22321 gaccttctaa atttaaagga tttataactc taccaacatc atgtacagct acaaaatcaa
    22381 ctacttttat atccttagtt tctttatcta ctaaaacttc agcaaaatgt acaccataag
    22441 aagtaagtcc agctggtgaa gaataatctt caacaacagt taactctctt aatgatttac
    22501 tttgactata tactgcgaca tcagaaagtg atgcttttac attttcatca agtttactaa
    22561 ttacatatcc attgtctaga tataaatctt cttttgatgt ttcaagtaat ttttctgctt
    22621 cttctactat aaggtttttc aatttctctg ctgtcttttt agctcctcca ccttctacaa
    22681 atacccctct acttgcatag tcaccaaggt tgaatgtaca tgcatccgta tcagtttcaa
    22741 atgtatcaac tttatcaggt gttattccta aaacttcagc taccatcatt gtttgcatag
    22801 ttacgacacc attacccata tcatgtgctc ctgttagtag tgtcaatgta ccatcttcat
    22861 ttaatttaag agtcaatgta acaacatctc tatgtgcacc aaaaactcca ttaccatgtg
    22921 cacctattgc catacctata cctcttaaat attttccttc ttcttttgga agttttttct
    22981 tttcatccca cttaaacatc ttcttacctt gctctataca atccaatact ctaggatttc
    23041 caagagaacc gcggaagatt atatcgacat catctggctc tactgcattt ttattttgaa
    23101 aatcgactaa atccatacct atttccttgg ctattttcgc aaattgagcc tgttgagcca
    23161 taaatatttg aggtgaccca tagcctctca tagctcctgc tattggtgta tttgtatata
    23221 caggcatccc agtaaacttt atatttggta ttttataaac tttaaatact ttatgactaa
    23281 gtgctcctat aacatttaaa gcacttgatg catatgctcc tgtatttgta tatattttta
    23341 tatcttgtgc tattacttca ccatctttat ttacaccagt ttttaatttt acaaaagacc
    23401 catgacgagt tcttgttgat atcatagatt cctttcttgt aagaaccatt ttaactggtc
    23461 ttcttgtcat ttttgataat gcggctgcta ctggttcaat tgtaagttct aattttccac
    23521 caaatgagcc tccaatagca ggtcttataa ctcttacttt atttaatgac atcccaaaaa
    23581 tttgagatag tattattcta aatccaaatg tattttggca aggtgtatgt acagttaatt
    23641 tatcattata atcatagtgt gcaattacac tatgagtctc tattgcacta tgatgtattg
    23701 ctggagtaga gtattcatct tcaaatatat agtcacattc cttgaagcct ttttctacat
    23761 ctcccccatt tatgttgttt tgagaaacta tatttgaatc tccatgtatg cagatagcat
    23821 cttcttttat tgcatcttgt atagtaaata cagctggcaa ttcttcatat tcaactttta
    23881 taagttttac agctttctct gctatttctg gagtctctgc agctactgct gcaacacggt
    23941 caccaacaaa tctaactgta tctgaaaata taacttcatt ttcaggtata ttgtgctcat
    24001 aaaatcttaa tgaaccattg tattttcttt gtgatgtatt gagataagta gctatagctc
    24061 taacacctac tactttctca gcttcacttg tatctatact ttttattttt gcatgtgcta
    24121 caggacttaa aagcatctta gcgtaaagta cattttgtgg tttcatatca gccacgtatt
    24181 tcatttgacc agtaactttt aaagctgcat cttttagagg gtatgatttt cctattacct
    24241 tttccataat tatctacccc ctaatctagc tgcagataat tttacagctt ctataatctt
    24301 tacatatcct gtgcatctac agagattttc tttaaaagct tctttaattt catcttcatt
    24361 aggagatgca tttctattta aaagagcttg tgttgttata atcataccag gagtacaata
    24421 tccacattgt acagctccaa cttctataaa agcttcttgt attggatgaa gattttctcc
    24481 attagcaaaa ctttctatag tgtatataac tttaccttcg cagttttttg caagaagttt
    24541 acaagatttc atgtcaactc catctatcaa aactttacat gctccacaac tgccactatt
    24601 acaaccttgt ttcgctccag ttagatttaa tttttcacga agtacatgca aaagagtttc
    24661 attcttttca acttctattt catacatgta atcattaata tttaatttta ttttttccat
    24721 tttctcctcc tacagataaa ctaatgttgt aatagaatat tattacaatc ttattttaat
    24781 attagtataa gctattccac ttatgtcctt ccattctatt agttacatta gctctcttac
    24841 ataattcttc tgctgcaagt tgtgcattaa gcaacacttg ttcttcactt tcaattgtag
    24901 ttacttttcc attttcaagt attacatttc catcaactaa aacactctct acattgtgca
    24961 tactagctga gtataccaaa gttgatacag gattgtgaag aggtattgat tttggagaaa
    25021 gcattgagtt aaatattact aggtcagctt ttttcccaat ctccaaagaa cctatttcat
    25081 cttccattct aagagttctt gctccctcaa ttgtagccat ttcaagaact ttctctgcag
    25141 aaattgccag agggtcacaa ttatttactt tgtgttgtaa agctgttaat ttcataagct
    25201 ctaccatatc ttgtgcgtta ttacttgctg caccgtcaag acctaaactc acatttatac
    25261 ctttttttaa catttctggc acaggtgcaa caccagaagc aagatacata ttacttgcta
    25321 cattatgaga aacttttatg tcatactttt taagcatttc catgtcttca tcagttatac
    25381 atacacaatg tactgctaca acttctggac ctactatacc ccatttttca agtaatttta
    25441 tatctatttc tccatgtata tcctttgttg ctgttcttgc aaattctgtt tcagatatat
    25501 gaactgtaaa atatgaatca tattctttaa ctatattcca aagcatctta cccatttctt
    25561 cagatatagc ccacattgaa gaaggagcta cacagatttt tattcttcca ttttctgaat
    25621 tatgatattt ttcgaatacc cttctcaaat ctttttcaac cgtttccaca tcttctataa
    25681 gctctttgtg aatacctaaa tctatacaac ctctacctac aacccctctt atacctaaat
    25741 ctttatatgc ctttactatt ccatctgtaa gtcctggtct attgtgagta tgcatataat
    25801 caaccattgt agttatacca ctttttaaac cttccataca tccaagcatt gcagcatcat
    25861 aagtatcttg ttctgttaag aattttgctg atggaaacat cattgtattt aaccactcat
    25921 gaagtgccat atcatcacct aaacctttta ataacacttg gaacaggtga ttatgagtat
    25981 ttataaagcc agggaatatt acttttccat tagcatctat aactttttta gcatcaagat
    26041 acttaggctc aatatcaact gtatttccta tatccaagat tctgtcacct tgaatagcta
    26101 ttgctccatc aaatataaca tctctgtctt tattaactgt aacaattatt gcatttttta
    26161 ttagtatatc aatcatctta aatccccctt tgaatacttt cattacaaca ttttaccata
    26221 tggttttctc atattatatc taatacattt atccaatatt ttcctcaaga tttgaagtaa
    26281 cgttttcagc acttttacgt gactttaatt taaataatgt ttgaagtaat atagctatta
    26341 ttgctccaga aactatactt gaccctccaa ggacagttcc aattgtttct gggaattggt
    26401 ctaaaacttg tggagcagtt gtaagaccca tacttgttgc tatagataca cctgctataa
    26461 gattgttttc ttcagtgaat ccatccatac tcataataga gaaaccagac attgctattg
    26521 atgagaaaac tactaaagtt gctccaccaa caacacaaga tggtatagtt gtcattattg
    26581 cacccaatgc tggagatatc cctgctagta ataatacaag tgcccctagt gctattacaa
    26641 atctacttgt aactttgttc atagatacaa ttactgtatt ttggctaaat actccagttg
    26701 gaagagctgc aaatagtgat gaaattatag aagttataga atttcctaaa acaactgatg
    26761 ctaattcttc gtcagttacc tctctatcca ttgctcctac tgtagctatt gtacaggcac
    26821 ccatcatatc agctatacct attatgtaaa taatagtaaa cattactatt aactctggtc
    26881 taaattctaa tccaaaagct gctggtgttg gtaaagatac tatagctgct ccttgaacgg
    26941 ctgagaaatc aaccaatcct aaaactaaag atatagcata acctactaat attcctatta
    27001 atattgaaga attttttact aaacctttac cgtatttatt tatcattatt attacaaaag
    27061 caactataac tcctactgtg aagtttattg ggcttccaaa tgtttgtgtg ccttctcctc
    27121 cagctaaatt ctttatagct gttgcgaata gtccaagtcc catacatgct attatagttc
    27181 cagaaactat tggagtgaat atatgtctaa ttttcttaac tccaaatcct acaaagaata
    27241 cgattacccc agcagcaatc tgtgctccaa atagagctgc taaaccatct ttagctgcta
    27301 ctgaaagaca agctcctaaa aatacataac tcattcccat cattacaggt aatcttgaac
    27361 ctaacttaaa tcctttaaat aaaggtattg gatataactg taaaaacgtt gctaaacctg
    27421 ctgctaacat agaaccctga atcaacattg ttgcttgccc ctggttaagt cctaccacgt
    27481 ttgctattaa tatcgcaggt accatatttc ctactatcat tgctaacaga tgttgtaagg
    27541 ccaaaggtat tgattccttt agtggtggta tcccatcgac atcatatttt gaagtattac
    27601 gtgttttcat aaaataaatc ctcccataca taaatatctt gactaaatat ttttataatt
    27661 attttctata aatattttta tgaccatgaa tttattgctc aaccgataaa cacagctaaa
    27721 ctgagctatt tttataaaaa attaacaaat ttctaaatat tccctccccg attttcaact
    27781 taaatgaaac attaattgcc tggtatatat ttatttgtta aattttttat taaaatgaat
    27841 agctatcaaa aataatctaa caatctcata ctaaataatt taaacaattc ttttaaatta
    27901 ttatatctta attagtctct tccataacag ctctttcttt agcctcatcc tctagacttt
    27961 tatttggtat tattagattt aaaacgaatg caaccaatgt tgcaattact attggagatt
    28021 ctccaaatac taactttaca aatgaaggaa atgcctcttg ggctgctggt actgatgtta
    28081 ttcccatgcc taaggcaatt gccaaaccaa caatggtaat atttcttgat gacaactctt
    28141 ctgtaataat taactttata cctgtcattg ttatcatact aaatatagat attgtagctc
    28201 ctcctaaaac agaatatggt atagtagtca ttaatgcacc aaatttaggc acaaaccccg
    28261 acaataacat aaatatacca gctattccaa gcacaaatct acttattact ttgttcatag
    28321 ctaccatccc cacgttttgg ctatatgatg atggtggtaa acctccaaac aaagctccta
    28381 tcatagtaca aattccactt cctattactc cacttgataa ttccttatct gtgatattcc
    28441 tatccatgcc tcccattgta gtagctgata aatctccaat tgcttgaaca gcattgatta
    28501 tacttacaat tactactgag attattacag gcatatcaaa ttccatccca aattcaagcg
    28561 gtttaggtat cgcaaaccaa gttgcctctc taatagggtc aaaatttatt atacccagaa
    28621 ctaaagatac acaatatcca actataattc ccaaaaatat tgctgccaat tttgcatatc
    28681 cttttgcaaa ttgactaaga cctataacta ccactaatgt tatagccgct actgcccagt
    28741 tttgcataga ggcataagta ggactattta caccacctgc catataattt attgctatag
    28801 gatacaaaga taatccaatt gtaaaaacca ctgttcctgc aactatattc ggaaaaaatt
    28861 ttcttatctt ttttatgaat atccctatta atactgtagc cactccccct attaattgtg
    28921 cacccaaaat gcttgctaat ccataatttc ctccgactgc tacaagtgtt ggtacataag
    28981 taaaaccaac tccaaaaatt ataggcaatc ttgaaccaat atttcctatt ggatatagtt
    29041 gtataagtgt tgatatacca gctattatta atgcatattg cactaaaagt gttatttgtg
    29101 tagggctaac acccacagct cctcctacga ctataggtac tgtaacagtt ccaactatca
    29161 ttgctagtat atgttgcatt gatagtggca aacactttaa aattggtggc cttccatcaa
    29221 tatcaaacat agaaacattc ttttgatatt tactcaaggt tatcactccc aactattttt
    29281 taatgacagt tattattatc tcacacaaca tcctttcttt ttttattttg tcatctcaat
    29341 ttaatatgaa gcaattataa tgccaatttt ttaacataat tgttttacat atataatttt
    29401 tattatattt gttagtattt gataatttat taaagcattt atttttttaa attcttttaa
    29461 atttttttta tttttggata ataaaatgct attacacaaa aaaacactta gaaaatagtt
    29521 ttccaagtgt tttttatcaa ttttataatt tcaaatttta gaattgagaa taaaaaacct
    29581 aattattata catctatttt tctgtacaat gtagctagtg atattccaag ttttttggca
    29641 gccagttttt tagacttagt atcatttccg taaaacttta acactttctt tatataggct
    29701 ctttcaaact cttcaagtgt aagtatgtct tgttccatac ttatctcata gtcactttcc
    29761 tcaagtaact ttatatttat attatttaac ttaaaatatt caagtatctt tctatttatt
    29821 attcctttat gtattattcc atcttcctca agaaggttta atgccagttc tatagtattt
    29881 tccaactctc taatatttcc tggccaagga tacttaagca acatttgttc cacatctggt
    29941 tctatatggt acacgttttt cttcattttt ctcgaatatt tgtctataaa attatttatt
    30001 aatatttgta tatcgtctcc tctttctcta agtggaggca cttctaaagg tattacattc
    30061 aatctatagt ataagtcttc tctaaattta ttttccttaa ccaactcaaa taaatctcta
    30121 ttagtagctg atatgattct aacatctata tcaattagtt catttgaacc tattctcgta
    30181 aacttctttt cctgtaatac cctcaataac tttgattgta gttgaattgg catatctcct
    30241 atctcatcta aaaatacaac ccctccattg gccaattcaa acttaccaat tttacctttt
    30301 gaatctgctc cactaaaagc tccttttgta tatccaaaaa gttcactttc tagtaaaggt
    30361 tctggtatag cagcacagtt tatagcaacg aatgttttat tccctctgtt tcctgcgaga
    30421 tgaatggctc ttgctattaa ttcttttcca gtgccacttt ctccagttat agctacagta
    30481 gaatcactat ttccaatttt gcaaattcta ttcttaagag cacgcattac atcagactct
    30541 ccaattatgg agtctactgt tgttgttccc caaatattat atacttccat tccaccatac
    30601 attactgaat cactgtgttt gtccataaaa tatcaactcc aaataagtat tctatataat
    30661 aatcattcac attatctatt taattatatc ataacagaaa agcttagtta taatttaata
    30721 atattatttt aaaacaaaac ttaataaaaa gtatatctac ttagttttaa tttgatagat
    30781 atactttctt cattttacaa aaatcctcta ttaaataagc aattacaatg cc
//
LOCUS       DAMJWO010000048        30461 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.049, whole genome shotgun sequence.
ACCESSION   DAMJWO010000048 DAMJWO010000000
VERSION     DAMJWO010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30461
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.049"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            230..1309
                     /locus_tag="PC366_002235"
     CDS             230..1309
                     /locus_tag="PC366_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDF2577746.1"
                     /translation="MPELLKNMYNRESLYEVAVAIQSVYNSFKVDEFIKSTMDETWNN
                     LELKARCRKISMSLGMYLPEDYKEALSILEKSVTGFYFAFFFPDFVEVYGQDEINWDL
                     SISALERNTEYWSSEFAVRAFIIKDEERMMAQMRKWSKHKSEHVRRLASEGCRPQLPW
                     GQAISKFKKDPTPVLPILEQLKTDTSTYVQKSVANNLNDISKTHPDLVISIAKDWYGK
                     NKSTNWIVKHGCRTLLKKGNRDVLALFGYDDTTSINLQDFTLETTSISIGEDLTFSFN
                     ILAKKATKTRLEYGIDYMKSNGKRNRKIFKISEVSLKENEKKSYMKKHSFADVSVRRH
                     YPGIHSITIIINGVEKGKLDFELGV"
     gene            1633..2001
                     /locus_tag="PC366_002236"
     CDS             1633..2001
                     /locus_tag="PC366_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HDF2577747.1"
                     /translation="MDVYSFWNDTLAQDAVKIRKYFHEDAYINWHDTNEHFTLEEFII
                     ANCEYPDKWNGKVERVLEFGNLVITVTHVYAINKPLSFHVVSFISLKDDKIISIDEYW
                     GEDDDVPQWRLDKHIGKPIK"
     gene            2118..2921
                     /locus_tag="PC366_002237"
     CDS             2118..2921
                     /locus_tag="PC366_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2577748.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDKQNMKKVVLIGQSAGGF
                     VAQSFIVKYPNMVEGLMMIGTCPYGTDYYSKSDIFWLKQTEWMLKLFPDKLLRNIISK
                     MCGATSEGRRSMMKMLEGYEKKELCHLMYLGFAGFMPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPSELNQIMDIFIKQLNI"
     gene            3306..4196
                     /locus_tag="PC366_002238"
     CDS             3306..4196
                     /locus_tag="PC366_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2577749.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKQAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSARFDAVKELNDSGIFCGILLTPMLPFLTDNKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVLKYQKTYGLNYVCTIQNKDSCEKLLREECARYGILTD
                     MKEIIKAYKRSESYIQIKFF"
     gene            4659..5102
                     /locus_tag="PC366_002239"
     CDS             4659..5102
                     /locus_tag="PC366_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2577750.1"
                     /translation="MIEIKTIEINKKSQIDLLMLADPCEEMIDKYLNKGTMYALYDNK
                     ELTCIAVVNEISKEICELKNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMVVGTSES
                     GVPFYEKFGFVYSHKIKNFFVDNYPEPIFEGELQCVDMLYLSYNF"
     gene            5274..5444
                     /locus_tag="PC366_002240"
     CDS             5274..5444
                     /locus_tag="PC366_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577751.1"
                     /translation="MDSNNNTIKSTVKKGISFGSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            5995..6903
                     /locus_tag="PC366_002241"
     CDS             5995..6903
                     /locus_tag="PC366_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDF2577752.1"
                     /translation="MTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFINDI
                     LKDAPYANRNIKPFTHIKRIIKAETDPTINYIGEKRPRLYILAEDEESNHINIEMQRA
                     LEDDYLERAEYYLSRVHGRKLEEGKEYKEIGKTVGIHILNHVKYNHIEDYVNCLRLTM
                     DGHPNIYSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIKR
                     ALDRLKELGSNEDYLLNLKRGAYIMNKSRNFKEEIFQEGVEKGKREEKFNIIIKLKNK
                     GYNLSEICDIIDDLNKSEVEKIYNQN"
     gene            7083..7571
                     /locus_tag="PC366_002242"
     CDS             7083..7571
                     /locus_tag="PC366_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HDF2577753.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     ITVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLSNVKLIKEFV
                     AK"
     gene            7657..8064
                     /locus_tag="PC366_002243"
     CDS             7657..8064
                     /locus_tag="PC366_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577754.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKVLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            8065..8283
                     /locus_tag="PC366_002244"
     CDS             8065..8283
                     /locus_tag="PC366_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2577755.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENNI"
     gene            9005..9310
                     /locus_tag="PC366_002245"
     CDS             9005..9310
                     /locus_tag="PC366_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577756.1"
                     /translation="MPSMIMEVVGVLFIAIGLILTFIEIKGNFPSFYGFGQNSIGKNA
                     VGIIAAGIALIFFRNGIDSIDSIATYGVFLAIELVVIVAYFLIRKKFTKEDKHLRTN"
     gene            9718..10407
                     /locus_tag="PC366_002246"
     CDS             9718..10407
                     /locus_tag="PC366_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2577757.1"
                     /translation="MDILLVEDDKNIREMVYDFLISENYFVKTAVDGNTAIEIFKNYS
                     FDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPF
                     SIVELLARIKANIRRATVYSSSRNSEDMVIQYKDLIINISKYVVSKNGIDLNLTHTEF
                     EIVKLLATNQGRAFSKEQLYNTIWKEPYYGNENVLNTHINRLRNKLSDGIEKNNYIKT
                     LWGIGYKMEEE"
     gene            10407..11324
                     /locus_tag="PC366_002247"
     CDS             10407..11324
                     /locus_tag="PC366_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2577758.1"
                     /translation="MELFLVVISIVLFAFYLKERNKSKKMESDYKYINSRLRDITNDD
                     EINYILVPSDISIVKETAVDINKLLEKFYSRQINYNRSEKAILQIFTNISHDLRTPIT
                     VLKGYIEMLYLQSQKEELSSSMRATLEKMQTNSNELVNSINNLFNMAKIQSGDMILNL
                     QKSNLTQLCHEIILEFYDLLDKENFNVEVNIEDRPIYANVDTEALQRILKNLIDNAIK
                     YGSDGRFLGISLYEKEKHVFIDIEDKGSGISETEKEHIFTRAYTADRKKGNGLGLAIS
                     QGLANSMGGSIYVNSRPNVKTVFTVKLKS"
     gene            11397..12323
                     /locus_tag="PC366_002248"
     CDS             11397..12323
                     /locus_tag="PC366_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577759.1"
                     /translation="MNYIIETHQLKKIYKDKAVVNDVNIHVKKGEIYGFVGPNGAGKS
                     TVMKMLLNLVKPNSGEIVMFSKKVAETDFEILKKIGTIIENPYFYENLTAKQNLDLHC
                     EYMGYYNKEHISEVLECVGLSKQSNKKVSKYSLGMKQRLAIARAILTKPELLILDEPI
                     NALDPEGIREMRELFRKLNTDYGITIFISSHILSEVEQIADTIGIIQDGKLIKEISMS
                     DIHKYQTDYVEVDVDNVELAGYLLEKEFGIKDFKITSESCIEIYDLRKDVKEISKIFI
                     KNQIGINSIGRKQSSLEDYFFQTTGTGGIETL"
     gene            12320..13000
                     /locus_tag="PC366_002249"
     CDS             12320..13000
                     /locus_tag="PC366_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577760.1"
                     /translation="MIHLMKLELKKVGLKRYFLFSILGILLCMFFVFTGLNDKSTSIY
                     DYDVTFRTISLVFCFYYIILFAVLNVAYIINEYTNKTILILFSYPLDRKKLILSKLLL
                     ITTLMISSMIVGYICCFTFVVVLDKYFNLVIGDFHISILSYWIPGAIKSIIVFCSLGI
                     WTFVVGMIRKSIPVTLVSSIIFINLRQFILAGTNTTQDSLISVFIIVGITVIGIYYIL
                     NHKVTEID"
     gene            13445..14146
                     /locus_tag="PC366_002250"
     CDS             13445..14146
                     /locus_tag="PC366_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF2577761.1"
                     /translation="MNNSFLDKLIETKELKNSLYNVLKHNFLYHSNKIEGSTFTTEAL
                     ALLLDKNVVTGRHTLDDVQETVNSSYVFDTVIDSLKEKITHNFLRNLHSSLIFNTTLH
                     SRGMAGIYKTIPNMILGTDVSIAQPFEVEPKLDELIEWYYSQSEVSIKVIAEFHYRFE
                     LIHPFQDGNGRIGRFVMLKQMLENNLPIKIVSWDSEDLYRNSLNSCSLGNYVPLIEYL
                     SSLEDFREVYKMLWK"
     gene            15050..15700
                     /locus_tag="PC366_002251"
     CDS             15050..15700
                     /locus_tag="PC366_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2577762.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEEEEV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
     gene            15978..18044
                     /locus_tag="PC366_002252"
     CDS             15978..18044
                     /locus_tag="PC366_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HDF2577763.1"
                     /translation="MKEVVESLKKITKERIENTMKKLFTSETFLEYQFISDCQISPDG
                     GYTAFIVKKADIKENGYTSQVYILNNKTGELKQITSINSVGAYVWEDENTILFPALRN
                     EKVKEAVKNGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYAVIDSYDNDRP
                     IVEGLPEEEQQKKINAYNKRHYEHFKEIPYAVNGEGYISRKRKRLYIYDSNINKLKAI
                     TAPMFNVVGMKISDGKILYIGQEFKDVKGLKNGVYVFDTNTNTNICILEKDKYIIKGF
                     ELYQNQVILNLTDALSYGNGENGDFYTIDIDTKEMKLLSGHQHHCIGNTVTSDVKMGA
                     GQTTKVDGEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVGCL
                     GNGLPEVYTVENGTLCKKTHLNDHILEEYKISVPEYIESKGSSKWEIQGYVYKPVDYE
                     VGKKYPAVLAIHGGPRLTYGPYFMHEIQVFTSAGYFVFFCNPRGSEGRGNAFADIRKQ
                     FGDIDYIDFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRS
                     IANWSSMEGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYADKCVTPTLFLHGEKDY
                     RCYMQEAFQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQKLQRLVEMLDWFSVYIK
                     KDNIGQ"
     gene            18061..20016
                     /locus_tag="PC366_002253"
     CDS             18061..20016
                     /locus_tag="PC366_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HDF2577764.1"
                     /translation="MEKIKIESSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKAGTTDFYTISIEGGE
                     AKEAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGVDYWTFTDKPFIRDR
                     ENFSQRRRVTLELYQEGENITKAITPKFCEVAGIDVSSDKNRILYTGQIYEDCATPFS
                     GLWEYHIDSGETKELVPQGKYQISLAKYIGKDKVMLQASTLERSITQNHDIFILDLST
                     SEINMIASPDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFNEFDTKTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSKPYLDTHKV
                     SLPEKLTFVAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDTCIEKYPGIDADRLGVA
                     GGSYGGYMTNWIIGHTDRFKAAVSQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIARANAIVDWFERYL"
     gene            20032..21222
                     /locus_tag="PC366_002254"
     CDS             20032..21222
                     /locus_tag="PC366_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDF2577765.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTAAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAENTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVIVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            complement(22070..22253)
                     /locus_tag="PC366_002255"
                     /pseudo
     CDS             complement(22070..22253)
                     /locus_tag="PC366_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427897.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22356..22730
                     /locus_tag="PC366_002256"
     CDS             22356..22730
                     /locus_tag="PC366_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2577766.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAN
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFVSTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMGILYEED"
     gene            22732..23589
                     /locus_tag="PC366_002257"
     CDS             22732..23589
                     /locus_tag="PC366_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577767.1"
                     /translation="MENILEVYNLNKTYTNFSLSNISFVLPEDCITGFIGVNGAGKTT
                     TIRSILDVVKRDSGKIKIFGKDFDGNEKELKNRIGVVFDDSYFYEELSMSEMKSIIAP
                     SYDNWCEEDYQQNMKRFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTEYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     DEHRKVKGDIQFLNDEIKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            23592..24230
                     /locus_tag="PC366_002258"
     CDS             23592..24230
                     /locus_tag="PC366_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDF2577768.1"
                     /translation="MLIHLVKKDILIVKKYVLLILFIAIGIPLFILWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFAMVFIYCTLVY
                     WIENLLIPQIGTFDLTYILIVLLISSIIYGVYMPIQYKLGYETTKFFFVMIIMASSFV
                     LPLTIAHSNFEIPFIYQYPSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            25204..25938
                     /locus_tag="PC366_002259"
     CDS             25204..25938
                     /locus_tag="PC366_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2577769.1"
                     /translation="MNLAKGLDVLKISSNVFGEDKVMYIPVIYTEDDATLIDTGLPGQ
                     GDLIIDALNKSNTSFDRLKNIIITHHDIDHIGNINYLREKSKNNIKVYAYKSEVSYIT
                     GEETPFKLYMLEQMVDKIDDKMLSMLNVMVLGFKSSYTKVDVSLDNHEKLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQVENGELTPVDVMHSNKQELKDAIKNISNYD
                     IETIVFSHGGLYQRDIIGTLKNLIIE"
     gene            27080..28336
                     /locus_tag="PC366_002260"
     CDS             27080..28336
                     /locus_tag="PC366_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HDF2577770.1"
                     /translation="MIEKFKTLIWIKMIIRIKSVYKTYGGLFLLGLIGIPVGAIIGLI
                     DTIFGTVLLKVTDIRETYPMYLIPFLAVVGVVIAYCYFKFGGKSSKGMNLIFEVGHGE
                     EEIIPLRLVPFIISGTWLTHLFGGSAGREGVAVQIGATFSHWVGKRLPIKNASSIFLV
                     TGIAAGFAGLFETPIAAILFAMEVLVAGSLEYQSLFPAFTASFTASAVSKTLGLEKFS
                     FALSSKVVFDLPIFWKLIVLGIIFGMVGGAFAWCLKLSKRKIGNRLKNPMIRIAIIGV
                     CLSVLFLLFYKGRYSGLGTNLIQNSFYGGEIYSFDWLLKFILTILTLSAGFQGGEVTP
                     LFSIGASLGVLLAGFFNLPIELVAALGYASVFGSATNTFFAPVFIGAEVFGYSYLPYF
                     FVVCAISYIFNMDKSIYSLQKISTKQ"
     gene            28399..29592
                     /locus_tag="PC366_002261"
     CDS             28399..29592
                     /locus_tag="PC366_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDF2577771.1"
                     /translation="MLTSLALIFLLGMASGGIFEKIKLPSLLGMLLTGIILGSYVLNL
                     IDNSILDISSDLRKIALIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIIGMIVL
                     APKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
                     FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIVGAVIGICLAVFFKKVHMRDSAK
                     GVLLLSISFLMISLETALEGIVPFSGLLAVMNIGIFLQIKYRVVARRLSVKYSKLWVG
                     AEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCM
                     IGYIPKATVQAAIGGVPLAMGIASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSV
                     EGKSK"
     gene            29799..30179
                     /locus_tag="PC366_002262"
     CDS             29799..30179
                     /locus_tag="PC366_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2577772.1"
                     /translation="MYLKKLSKLELVIMKFIWNLDIKTNSYEIIDYMKEEHNLPEKVA
                     LKILSKLSKKRFLYVQETGKCMYYTVAIKEKTYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEELTEEKIKSLENWVVNWEEAYI"
BASE COUNT        11595 a         3227 c         5213 g        10426 t
ORIGIN      
        1 agtaaagtat aaaattctat tactataata aaagatagaa ctagaagtct ttatgaaagt
       61 gggaaaagta tttatataaa taaatttata tggtttatag tttaacagta ggaaatatcg
      121 tatgagtgag aatatcgtat tttacataaa gatttagcaa tatgacacac tgttgtcgtg
      181 ttctgtagga tatgattaat aaatcagata tgaaaggaga gtgagtaata tgccagaatt
      241 actaaaaaat atgtataatc gtgagtcact ttatgaagtt gcagtagcta tccaatcagt
      301 ttacaactca tttaaggtag acgagttcat aaaatctaca atggatgaga catggaataa
      361 cttagaatta aaagccagat gtcgaaagat aagtatgagt ttaggaatgt atttaccaga
      421 agactataag gaagctcttt ccattcttga aaaatcagtt acaggttttt attttgcttt
      481 tttctttcca gattttgttg aagtttatgg gcaggacgaa ataaattggg atttatctat
      541 aagtgcatta gaaagaaata ctgagtattg gtcttcagaa tttgctgtaa gagcatttat
      601 catcaaggat gaagagcgta tgatggcaca gatgcgtaaa tggtctaagc ataagagcga
      661 acatgtacga agacttgcaa gtgaaggttg tcgtccccag ttgccttggg gacaagcaat
      721 atccaaattt aaaaaagacc ctacacctgt actgcctata ttggagcaac ttaaaacaga
      781 tacatcaacg tatgtacaaa agagtgttgc taataatcta aatgatatct caaaaacaca
      841 tccagattta gtcataagca ttgcaaagga ttggtacggt aaaaataaat ctactaactg
      901 gattgtaaag catggttgta gaactctact aaaaaaaggc aatcgtgatg tattagccct
      961 ttttggatat gatgatacta cttctataaa tcttcaggac tttactttag aaacaacgtc
     1021 tatttctatt ggagaggatt taactttttc atttaatatt ttagcaaaaa aagcgacaaa
     1081 aacaaggctc gagtacggaa ttgattatat gaaatctaat ggaaaaagga ataggaagat
     1141 atttaaaata tcggaggttt cattaaaaga aaatgagaaa aagtcatata tgaaaaaaca
     1201 ttcatttgca gatgtaagtg taaggagaca ttatccaggt atccactcga ttactattat
     1261 tattaatggg gtagaaaaag gcaaacttga ttttgaatta ggtgtataat tttactaaca
     1321 gcataaccta tatcagatac tttgctaaac ctatatcgta tactctaata aatctatatt
     1381 aggtagttta ctacttgttt actgaattta aatacaaaga aatacaggtg ttaatccctg
     1441 cccattaaag gaatatgagc ataacacaaa agtagaactt atcaattctg ttacgggtat
     1501 agtagtaaat ccatagaatc acaattagaa gatgaagtgt aaaaaataag ttagtgttga
     1561 ttttagttgc tagtgatatt gaatagttat acaatagcca tataaattag aatttgtaga
     1621 ggagaaatgt aaatggatgt atatagtttt tggaatgaca ctttggcaca agatgctgtt
     1681 aagataagaa aatattttca tgaagatgct tatattaatt ggcatgatac aaatgagcat
     1741 tttactttag aagaatttat tattgcaaat tgtgagtatc ctgataaatg gaatggtaaa
     1801 gtagaaaggg tgctagaatt tggaaattta gtaattacag tgacacatgt ttatgcaata
     1861 aataaaccac tatcatttca tgtcgtttca tttatcagcc ttaaagatga taagattatt
     1921 tctattgatg aatattgggg agaggatgat gatgtgccac agtggagatt agataaacat
     1981 attggaaagc caataaaata gtgtttgttc tgttttataa ctgaaatttt gataacattt
     2041 gatattttga tttgtcattg gtcaacatag tcgttagtgt aataatttaa aaaagtagaa
     2101 tttggagagt gagcactatg gaagaaaaat acatcttatc tgaccgaggt aaagtatatt
     2161 attggataaa agaaagtaat agtgtgtttg caaagaactt aatttttttg ccaggactaa
     2221 cagcaaatca tcatcttttt gatttccaga tacagtactt ttcaaaaaat cataatgtat
     2281 tggtatggga cgctcctgct catggaaaat caagacctta cttagatttc tcatattcta
     2341 acttggtaga agaattgaaa gtaattttag ataaacaaaa tatgaaaaag gttgtactta
     2401 tagggcaatc ggcaggggga tttgtggcac agtcctttat tgtaaaatat ccaaatatgg
     2461 tagaaggatt aatgatgatt ggaacttgtc catatggaac tgactattat agtaagtcag
     2521 atattttctg gttaaaacag actgaatgga tgttaaagtt attcccagat aaattgttgc
     2581 gaaacataat atctaagatg tgtggagcta cgtctgaagg cagaaggagt atgatgaaaa
     2641 tgttagaagg ctacgaaaaa aaagaactgt gtcatctcat gtatctggga tttgctgggt
     2701 tcatgccaga aattcaagac ttaaatatac attgtccagt ttgtttggtg gttggagata
     2761 aagacaagac gggtaaagtg agaaaatata atgagcagtg gcacaataag actgggtatc
     2821 cattgcacat tataaaaaat gcttcacata atgtaaatgt cgataaacct agtgaactaa
     2881 atcagattat ggatatattt attaagcaat taaatatata aaaactacat actcattagg
     2941 taaattatgt agtatatgtg tttacatatg gttatagaaa taaatatgta ataaactact
     3001 taacacttaa aaagtggatt tgtccagagc ataatacaaa gcatgatata taaattttta
     3061 agcgaaatac atcaaaagaa gtattagaat tagtggagat aaaacagcta ttagagatta
     3121 taaataaata gttttaaagg tactacgaat atagaggaag gtaaatcata cgttattcaa
     3181 ggattataaa tgagtagttt aaaagtacta tcggataggt ctctgcatat ttaaacctta
     3241 gtaaaggtag ttaaagtagt agtttaaaaa ctaaaaaatt atataaagga attaggtata
     3301 agaaaatgat tgagagtata ccagcaaaac aaattttaca aaaagtgaaa tttgacaata
     3361 caagatggtt tggaattgac tataatatga atctctatcg tggttgttct catggatgta
     3421 tatattgtga tagccgtagc acaatataca acatagagaa ttttgacaaa gttagatata
     3481 aagaaaatgt gatagagatt ttaagtaaag aattgcgttc aaaaagaaaa aaaggggtag
     3541 taggcattgg agctatgtct gacacatata atccttttga aaagcaactt tgtattacaa
     3601 agcaagcact agatttgatt tcggaaaatc attttggagt gtctattgat actaaaagta
     3661 gtttggtggt tagagatata ccgattttgc agaaaattaa aaaaaataat tctgctattg
     3721 taaagttgac tataaccact gcaaatgatg aattatcaaa gaaaatagaa ccttatgtaa
     3781 atccaagttc tgcacgattt gacgcagtga aagaacttaa tgattctgga attttttgtg
     3841 gcatattatt gactcctatg cttccatttt tgactgataa taaagatgaa atacgagcaa
     3901 ttgtagaaaa agcacacaag gctaatgcaa agtttattta ttgcatgtat ggtgtaacaa
     3961 tgcgtagtgg tcagagagag tttttttatg agcatttaag agatatatca ccaaaattag
     4021 tacttaaata tcagaaaaca tatggtttaa actatgtatg tactatacaa aataaagatt
     4081 cttgtgagaa gttgttaaga gaagaatgtg cacgttatgg tattttgaca gatatgaaag
     4141 agattataaa agcgtacaag aggtcggagt catatattca aataaaattt ttttaagata
     4201 ggctttggat gagatataat agtggtgatt gatgtgttga tattatagtt gattgttaga
     4261 gaggatatta tagatgaata ttaatattga tattctaggt aattgctaga actaatatta
     4321 tagatgaata ttagtattga tattctaggt aattgctaga gttagtatta tagatgaata
     4381 ttagtattga tattctaggt aactgctaga gctaatatta tagatgaata ttagtattga
     4441 tattctaggt aattgctaga gctgatatta tagatgaata ttagtattga tattctaggt
     4501 aattgctaga gctgatatta taatttatta ttaatattaa tattctaggg aattatcact
     4561 atattttaaa aagtaaaaat atatatcaaa atgaactaaa taagtactgt aagaagtttg
     4621 ttaaattaag gtttgaataa agtgagggtg gagaacttat gatagaaata aaaactatag
     4681 aaataaataa aaaaagtcaa attgaccttt taatgttagc cgacccatgt gaagaaatga
     4741 ttgataaata tctcaataaa ggaactatgt acgcattgta tgataataaa gaacttactt
     4801 gtatagcagt tgtaaatgaa atttccaaag aaatatgtga attaaaaaac attgctacat
     4861 atgagcattt tcaaaatatg ggttatgcct caaagatgat ttatcatctt ttagatgttt
     4921 atagtaaaaa atattcatca atggttgttg gtacatctga aagcggagtt cctttttatg
     4981 agaagtttgg atttgtttat tcacataaaa ttaaaaactt ttttgtagat aattatccag
     5041 aaccaatctt tgaaggagaa ttacaatgtg ttgacatgtt gtatctatca tataactttt
     5101 agataggata atatttttag gtagatataa ttaattaatt catataatta tcggaattat
     5161 aatttataaa ttatgtataa taagagtata atttatttag aagctgttat attgtattat
     5221 attcaaataa gatatataat aatttgttta ttttgaattt tggaggatta attatggatt
     5281 caaataataa tactataaaa tcaactgtta aaaagggtat ttcttttggt tcttgtttag
     5341 caatgattat ttcttatact gcatggaaat ctattccatg ggctattttt catggcttaa
     5401 tgagttggat atatgtactt tattattggg ttaagtatgc atagattaaa ttaataaata
     5461 agtatgtaat attgtaaagt ttaagaaaca aaatgtaagg gagtgtctcg aagtgaactt
     5521 tttagtttat aaggcactct tttttgtatt aaataaaata tattttcatt acttaaacaa
     5581 tgaaaaagat gagtatctct attttaatac atacccttat attcattcat ttatcaacaa
     5641 tagttttaaa aagaaagcta tctaaaatct attgtaatct aagtgcttct ctttaaagtc
     5701 ttaactttag taatgatata taagtttata aggttcttat ttcaataatg caaattttac
     5761 ttagaagttc agactttggt atgaagaaat gggtaataat aaaaaagagg tgttgatatg
     5821 aaagaaaaat tagaagaaaa atctaagatt attaaaacat caaaagagta taaacgaact
     5881 ataattgaag aaaaggacag agaatgaacc aaaaaattaa atgacatact tagtagaggt
     5941 gatttttcta atgaaaaatt agataaaatc aaggatttaa ttccaaaaga aatattgact
     6001 agtgaaaatg ttggagaagt tgtaactgaa gatgggtatg ctaagcctga gtatgatgag
     6061 gtatttaaat cattgtttac tttaaataat gattacgatt tacttgcaaa ttttataaat
     6121 gatatcctca aagatgctcc atatgccaat aggaatatca aaccgttcac tcatataaaa
     6181 agaataatta aggctgaaac cgacccaaca attaattaca ttggtgagaa aagacctaga
     6241 ctttatattt tggctgaaga tgaagaaagt aatcatataa atattgagat gcaaagagct
     6301 cttgaagatg attatttgga aagagctgaa tattatctta gtcgtgtaca tggtagaaag
     6361 ttagaagaag gtaaagagta taaagaaatt ggaaaaactg ttggaataca tatactaaat
     6421 catgtaaaat ataatcacat agaagattat gtaaattgcc tgagattaac aatggacggg
     6481 catccaaata tttattctag taaaactgca ttatatttta tagaacttcc aaaaattcgt
     6541 aaatccagtt gtatagcaaa cagagttcta atatggggta aacttattga taatccttct
     6601 catattgata ttagaatact atctaaaaca gattatgtta ttaaaagagc acttgataga
     6661 ttaaaagaat taggcagtaa tgaggactat ttattaaatt taaagagagg tgcgtatatt
     6721 atgaataaaa gtagaaattt taaagaagaa atttttcaag aaggtgttga aaaagggaaa
     6781 agagaagaga aatttaatat catcataaaa ttaaaaaata aaggatataa tttgagtgaa
     6841 atatgtgata ttatagatga tttgaataaa tcagaggttg aaaaaatcta taatcaaaac
     6901 taatactata attgagatgg cactagataa atataaagct tcctctttta aatttaaatt
     6961 aatataaaac cttgttattt aactatagta gatacaaaga gatatataag ctaaggagat
     7021 gattcaaaat aaaagtttga actatctcct tcttatagaa aaacaaaggg gttgatttat
     7081 atatgaaatt ttatactata cagactttag aattttggaa caacaataaa aacaataaat
     7141 atctatcaaa tgattattct tttatattag aagactttga tattccatac aaatggatgt
     7201 atagtcaaat gacaaataga atatatgaat ttgatgatag tatgatatgg gtttggacga
     7261 agagacctga tttaagatgt agtggttatt tagaaaaagg aaaaaaaggt gttttacttg
     7321 aaatagaaat aagtgaagac aatgtgttat tatcagaatt tgatttatgg catttacctt
     7381 taatggatat tactgtagag ctttatgaag atgaacaaat tgaaaagaag gtaagttggg
     7441 aaagaatatt tgacttagaa ctgtgttcaa aattaaatga agttaatata gaagatttga
     7501 cattgcaagg agtgacatct aaagtgcctc tatctaatgt aaaattaata aaagaatttg
     7561 ttgcaaaata atatttttat tgaaatttat tcaaaaaagt tatatattta taacaagagg
     7621 tgttataaat acataacttt ttaaggggga ttttatatgt ctaaacaaca aactggtatt
     7681 aaatcaacac ttatttcaga aatattggga atttcttatt gtattggagc tacattagta
     7741 aataagtatt tttttaaagg aagtagtatt gaatatcttc ctataattat ttgggtatta
     7801 gctatgggag ctcagtgggt ctataataaa aagtatgatg atttaattga tgaggcatca
     7861 aaatgtatac tatcaagagt taatgatatt gcaataaaag tattgttttt ttctgtagct
     7921 atagtatcta tatttcttgt aactttggac ataaatgtgt caaatttaaa tataggaatg
     7981 tctttattag tcattttgtt tattcaatcc ttgttgaagt taattctatt tatatatttt
     8041 gacagaaagg ggatatacaa ttaggtgtca gtattactaa agacaaaaat taaatcctat
     8101 agagaaaaga atcttatgac acaaggtgaa cttgcaaagt cagtaggagt aagacgtgaa
     8161 actattgtac atttagaaaa tggtcgctac aatccttctt taaaactggc aatggatatt
     8221 gctaaggtat ttgatacaac tgtagaagag ttgtttgaat ttattgaaga aaataatatt
     8281 taaatttcat gtattactta tgcattagag aatgaattaa tagataaaaa attcaagttt
     8341 atgtattaga gaatgaatta attataggta aaaaaccaag cttatagatt agagaataaa
     8401 tgacttatag atgaaaaacc aagctcatag attaaagaat gaatgattta tagatgaaaa
     8461 agaaagctta tagattagag aatgaattaa ttataggtaa aaaacaagct aatagattaa
     8521 aaaatgaatg atttatagat taagaagtaa gcttatagat tagagaataa atgacttata
     8581 aataaaaaga aagcttatag attagagaat gaattaatta taggtaaaaa acaagcttat
     8641 agattagaga ataaatgact tataaataaa aaccaagctt atagattaga gaatgaatta
     8701 attataaata aaaaccaagc ttatagataa gaagtccatg cttataagcc agaaaatgaa
     8761 tactttaata gattaaaaaa tacatatttg tgaattatag aatgaataac tccataaact
     8821 agaaaattta taataatatc tatatgaaaa ttagaattat tttatcacaa aaaaattaag
     8881 ttaaataaat atgaaattac ttccaaatat acttccaaaa acatgtaatc gcatatataa
     8941 tataattata aaaataataa atatttttat agtagtagtt aattattaat aaggaggggt
     9001 caaaatgcct agcatgatta tggaagttgt aggagtacta tttatagcta ttggattaat
     9061 cttgacattc attgaaataa aaggaaattt cccttctttt tatggttttg gtcaaaattc
     9121 tatagggaaa aatgctgtag gtattatagc agcaggaatt gctttaattt tctttagaaa
     9181 tggcatagat agcatagatt ctatagctac ttatggtgta tttttagcaa tagaacttgt
     9241 tgtaatagtt gcatatttct taataagaaa aaaatttact aaagaagata aacatttaag
     9301 aactaattaa ctaaattatc tactataaaa ttggaaaatt aaaaacaaat aaaagtttgt
     9361 ttttaattat ttaaaatccc aatttgatta tttttaaaga aactatattc tgtataaaac
     9421 tagaatgtgg tttctttttt atgtataaaa tattttttag caaaagttaa aaggtgtttt
     9481 ataatataaa atagttaatt gtagatgtta ataaaagaaa attatgtata tttcagataa
     9541 agataagaga gtatactata ttttaattat tttttcaata aaacttattg aaaagaactt
     9601 taacttagaa gagtatcacc aaattgcaga tacaatatca taagcagtta tttattgaca
     9661 acccttttta ataaatatat catttgaagt atactgacga aaaggagttg aataataatg
     9721 gacatcttat tggttgaaga tgataagaat attcgagaaa tggtatacga ttttctgatt
     9781 agtgagaatt attttgttaa aactgccgtt gacggaaata cagctattga aatatttaaa
     9841 aattattcat ttgatattat tttactggac ttgatgttac caaagtctag tggttttgaa
     9901 gtattaaaat atatacgaag tgtgagtgtt gttcctgtta ttattactac tgcgaaagat
     9961 agtgacacag ataaaatgct agggcttaat cttggtgcag atgattatat tacaaagcct
    10021 ttttcaatcg tagaattgct tgcaagaatt aaagctaata ttagacgtgc aacggtgtat
    10081 agcagttcaa gaaactctga agatatggtt attcagtata aagatttgat tataaacata
    10141 tcaaaatatg tagtttcaaa gaatggaatt gacttaaact taacacatac agaatttgaa
    10201 attgttaaat tactagcgac taatcaagga cgtgcttttt caaaggaaca attatacaac
    10261 actatttgga aagaacctta ttatggaaat gaaaatgtgc taaatactca tattaacagg
    10321 ttaagaaata aattgtctga tggtatagaa aaaaataatt atattaaaac tctttgggga
    10381 attggctaca aaatggagga agaataatgg agttattttt agttgtaatt tcgattgtac
    10441 tatttgcttt ctacttaaaa gaacgaaata agtcaaagaa aatggaaagt gattataagt
    10501 atatcaattc aagacttcgt gatataacaa atgatgatga aattaattat attttagtac
    10561 catctgatat ttcgattgta aaagaaacag cagtagatat aaataaactt cttgaaaagt
    10621 tttacagtag gcaaattaat tataatagaa gtgaaaaagc gatattgcaa atatttacaa
    10681 acatatcaca cgatttacga actcccatca cagtattaaa gggttatatt gaaatgctat
    10741 atcttcaaag tcaaaaagaa gaattatctt cttcaatgag agcaactttg gaaaaaatgc
    10801 aaacaaattc aaatgagctt gttaattcaa taaataacct gtttaatatg gcaaaaatcc
    10861 aatctggaga tatgatatta aatcttcaaa aatccaatct aacacaatta tgtcatgaga
    10921 ttattttaga gttttatgat ttactagata aagaaaactt taatgttgaa gttaatattg
    10981 aagatagacc tatatatgca aatgttgaca cagaagcatt acaacgtata ctcaaaaatt
    11041 taattgataa tgctataaaa tatggttcag atggtagatt tttagggatt tcactatatg
    11101 aaaaggaaaa acatgttttt atagatattg aggataaagg ttcaggtatt tctgaaactg
    11161 aaaaagagca tattttcaca agagcttata ctgctgacag aaaaaaaggc aatggtttag
    11221 gtttggctat ttctcaaggg cttgcaaact ctatgggagg ttcaatttat gtaaatagta
    11281 gacctaatgt aaaaacagtt tttacggtaa aattgaaaag ttagaaaaaa gttagattta
    11341 aaagagagaa aagataattt tattttgtat actgttttta gaaaggaggg agtatgatga
    11401 actatatcat agagacccat caattaaaga aaatatataa agataaagct gttgttaatg
    11461 atgttaatat tcatgtgaaa aagggagaaa tttatggatt tgttggacca aatggagcag
    11521 gtaaaagtac agtaatgaaa atgttgctaa atctcgttaa gccaaattct ggagaaatag
    11581 ttatgttcag taagaaagtg gcagaaactg attttgaaat attaaaaaag attggtacta
    11641 ttattgaaaa tccttatttc tatgagaatt tgactgctaa acagaatctt gatttacact
    11701 gtgaatatat gggttattat aacaaagaac atatatcaga ggtattggaa tgtgtcggat
    11761 tgtcaaagca atcaaacaag aaagtttcaa aatattcttt agggatgaaa caacgtcttg
    11821 caatagctag agcaattctt actaaaccag aattattgat tcttgatgaa cctataaatg
    11881 cactcgaccc agaggggata agagaaatgc gagaattatt ccgtaagtta aatacagatt
    11941 atggaataac tatatttatt tctagtcata ttctttcaga ggtagaacaa attgcggaca
    12001 ctattggaat tattcaagat ggtaaactta ttaaagaaat ttctatgtca gatatacaca
    12061 aatatcaaac agattatgtt gaagtagatg tagataatgt ggaacttgct ggatacttgt
    12121 tagaaaaaga atttggaata aaagacttta aaattacttc ggaaagttgt attgaaatat
    12181 atgatttacg aaaagatgta aaagaaatat ccaaaatatt tatcaaaaat caaattggta
    12241 taaatagcat tggacgtaaa caaagttctt tagaagatta cttcttccaa actacaggta
    12301 caggaggtat agaaacacta tgatacattt aatgaaacta gaattaaaaa aagttgggct
    12361 aaaaagatat tttttatttt caatactggg gattttgtta tgtatgtttt ttgtctttac
    12421 tggattgaat gataaatcta cttcaatata tgattatgat gttacattta ggacaatcag
    12481 tttagttttc tgtttttact atattatatt atttgctgtg ttgaatgtgg catatataat
    12541 aaatgaatat acaaataaaa caatcttgat tttattctct tatccacttg accgtaaaaa
    12601 acttatttta tcaaagttac ttttgattac gactcttatg atatcatcaa tgatagttgg
    12661 atatatctgt tgttttacat tcgttgttgt gttggataag tattttaatt tagttattgg
    12721 agattttcat atttcaattt tatcttattg gataccagga gcaattaaaa gtattattgt
    12781 attttgctca ttaggtatat ggacattcgt tgttggaatg ataagaaaat caatacctgt
    12841 tacccttgtc agttcaatta tttttatcaa tttaagacaa tttattttag ctggtacaaa
    12901 tacaactcaa gacagtctga tttctgtttt tattatagtt ggaataactg tgattggtat
    12961 atattatata ctaaatcata aagttactga aattgactag atactgtgga taggaaggta
    13021 gttattaatt gtatcttctt gggataataa tgatttgcta ttatatcagc tattattaat
    13081 attattagag ttttaataat attaataata gctatatatt ttttcttctt atttataaat
    13141 ttaatgattt atagtcataa aatgaactct aagaagagat aaaaatgcgt tttatatgtt
    13201 tttagattaa tatgaaatat cacaatgaaa tgttgtacaa agtgatatat aataattata
    13261 tgaactataa aattgactaa acttattgac taataaatta gatgaaaagt tgagacttac
    13321 tgaaaataaa tacaatgaaa tatatactac aagtattaaa ttaaatctga actttacata
    13381 ctattagaat aagtattata agattataat gatttaaaaa tattaaaata attgaggtga
    13441 taacatgaac aattcctttt tagataaatt gattgagaca aaagaactta aaaattcact
    13501 ttataatgtg ttaaaacaca attttcttta tcattctaat aagatagagg gcagtacttt
    13561 tactactgaa gcattagcac ttttactcga taagaatgtt gttacaggaa gacatacttt
    13621 agatgatgta caagaaactg ttaattctag ttatgtattt gatacagtaa ttgactcact
    13681 gaaagagaaa ataacacata atttcttaag gaatctacat tcaagtttaa tcttcaatac
    13741 aaccctacat tccagaggga tggctggtat atataaaact atacccaata tgatactagg
    13801 aactgatgta agcatagcac aaccatttga agttgagcca aagcttgatg aattaattga
    13861 atggtactat agtcagagtg aagtgtctat taaagttata gctgaatttc attatagatt
    13921 tgaattgata catccatttc aagatggtaa tggtcgcata ggtagatttg ttatgctaaa
    13981 acagatgtta gaaaataatc ttcctataaa aattgtatct tgggatagtg aggacttgta
    14041 tagaaactcc ttaaattctt gtagtttagg taattatgtc cctttaattg aatatttatc
    14101 aagtttagaa gattttagag aagtatataa aatgttatgg aaataattgt ttgtagcaaa
    14161 aaaagttttt atataaatat atttttaact atgctattta acgttgattt cttagttatt
    14221 cttagcttgg actataccca ctattttaac tatataaaat agtggatata gtttaactat
    14281 ctctttataa ctatttttat gtatcttagt tgtttcttaa tattgggaca gttcataaaa
    14341 ctaaaagtga tttttaattt tatcatttat aatttaccat tacatcagaa aaatgcttat
    14401 cattagaatt ttcataaaag gtacctattt tcttcaatta actaaatcaa ttctattagt
    14461 cttaatcttt cgtatttcaa attgataata caagaaaata aaaaataaaa aattttaaat
    14521 tttttattta ttgcgaaaaa aataaaaagg tgctatactt tttgtaacat attattcaaa
    14581 ttattaagag atagtaaata tttatagttt aatttgtagt acactagcat gatttgcaga
    14641 acaatgaatt aatctatagt ataatagttt aatttgaagt acaacgattt aatctatagt
    14701 acactagcat gatttgaagt ataacgattt aatctatagt acaataactt gatttgcaat
    14761 acaataattt aatctatagt ataatagcat gatttgaagt ataacgattt aatctatagt
    14821 acaataactt gatttgaagt acaacgattt aatctatagt acaataactt gatttgcaat
    14881 acaatgattt aatctatagt ataatagcat gatttacagt acaataattt aaattgtagt
    14941 acaaaagtac tatcaaataa gaatttctac tttaaaaata ttactaaaag taattaaaat
    15001 ccaataattc aatataatat ggcaaaagaa tagaaataag gtgagagtag tgaaagtaaa
    15061 gtcaaattta gatgaaattt tatatcataa gattattgaa agtcttattc gtggtgaata
    15121 ctctgtaggt caaaaaatat tactaaatga cctttgtgaa aaatttgaag taagcagaac
    15181 accagttgta caagcagtaa aaatgctaaa taaagatgga gtgcttacta ttatgacaaa
    15241 tggtaaagtg tacgtaccag agtatgaata tgatatggta aaacaagttt gtgaaacgag
    15301 aacactgatt gaaacatatg ctttagaaaa aatgatgcaa gaagaggaag aggtttttca
    15361 acaaaagcta gatgtaataa aaagatactc tgataaatgc gaggagtact atcgtcaaga
    15421 aaaatctgta gaacttgcac tagcagattt ggaattacat aaagccattg tagaaggggc
    15481 aaataatgag attttaaatg atgtatatgt tggtatacaa ggaagattta tagtagtgaa
    15541 ctatttaatt cgaccattaa aaaatcgtaa ttatgaagga acagtacaag accattttga
    15601 aatattaaaa ttcattgaag acagagatac aaaaaaagca gtagataaac taagaaatca
    15661 tattcaagga actattaaaa gattctgtga agatgaataa taagttttga agttactata
    15721 tacttatcta ttaagttgct aaatgtagtc taagtataat ctaattatag tttaaacata
    15781 atctaaatat aatctaaata tagtgtaaat aagtctaagt atgaattaaa tatagattaa
    15841 gtatgaatta agcatggatt aaatatactt taaattacaa atattacaag gaagccagaa
    15901 ggcttcctaa aaaaataacc tttataaaat tttttatttt aaatttaaaa ttttttattt
    15961 taaatttaaa ataaaaaatg aaagaggtgg tagagagttt gaaaaaaatt actaaagaaa
    16021 ggatagaaaa tactatgaaa aagctattta cgagcgaaac atttttggaa tatcaattta
    16081 taagtgattg ccaaatatca ccagatggag gatatacagc atttattgta aaaaaagctg
    16141 atatcaaaga gaatggttac acaagccaag tttatatatt aaacaataaa actggcgaat
    16201 taaaacaaat aacgtctata aactctgttg gagcatatgt ctgggaagat gaaaatacta
    16261 tcttgttccc tgctttgcga aatgaaaaag taaaagaagc tgtcaaaaac ggtaagcaat
    16321 gcatgagtta ctatgcttta tctttaaatg gtggagaagc agaagaactt tttagactcc
    16381 ctatcaaagg tggtaaattg aatcctatag gaaaaggttt gtatgcagtt attgattctt
    16441 atgacaatga ccgacctatt gtagagggat tgccagaaga agaacaacag aaaaaaataa
    16501 atgcttataa caaaagacat tatgaacatt tcaaagaaat tccttatgct gtcaatgggg
    16561 agggatatat tagcagaaaa agaaaacgcc tatatatata cgacagtaat ataaataagt
    16621 tgaaggcaat tacagcacct atgtttaatg ttgtaggtat gaaaataagt gatggaaaaa
    16681 tcttatatat agggcaagag tttaaagatg taaaaggttt gaaaaatggg gtctatgtat
    16741 ttgatacaaa cacaaacaca aatatctgta tattagaaaa agataagtat attataaaag
    16801 gttttgaatt atatcaaaat caagtgatac taaacctaac tgatgcttta tcttatggaa
    16861 atggagaaaa tggagatttt tatactattg atattgatac gaaagaaatg aaacttcttt
    16921 cagggcatca acatcattgt attggaaata cagtaacatc tgatgttaaa atgggtgctg
    16981 gtcagacaac aaaggtagat ggagaatata tttattacac ttctacagta gatatggact
    17041 gcattattga aagaatacat attccaacag gaaaacagga aaaagtaaca cagacaggtt
    17101 cagttgattt tatagatgta aaagatggca atattgtatg tgtgggttgt ttaggaaatg
    17161 gattaccaga agtttataca gtagagaatg gaacattgtg taagaaaaca catttaaatg
    17221 accatatttt agaggaatat aaaatttctg tgccagaata catagagtca aaaggaagtt
    17281 ctaaatggga aatacaagga tacgtatata aaccagtaga ttatgaggtg gggaaaaaat
    17341 atccagctgt attggcgatt catggaggac caagattgac atatggacca tattttatgc
    17401 atgagataca ggtatttaca agtgcaggtt actttgtatt cttctgtaac ccaagggggt
    17461 ctgaaggtcg tggcaatgct tttgcagata ttaggaaaca gtttggagat attgattata
    17521 tagattttat ggaatttaca gatactgtac ttgaaaaata tacagacatt gataaaacaa
    17581 aattggctgt tgaaggtgga agttatggtg gatttatgac gaattggata attggtcata
    17641 caaaccgttt tgctgttgct tgtgctcagc gttctattgc aaactggagt agcatggagg
    17701 gtacaacaga cattggttat tatttctgca aaggacaaac aggtgcttct catatggaaa
    17761 accacgagct tcaatggaaa cagtcacctc ttgcttatgc tgataaatgt gttacaccga
    17821 ctttattttt acatggtgaa aaagactata gatgctatat gcaagaagca ttccagatgt
    17881 tttcagcatt gaaaattcat gggtgtccta caaaactttg tctatttgaa ggggaaaacc
    17941 atgaactgtc tcgttctggt agaccaaaac aaaagctaca aagattagtt gaaatgctag
    18001 attggttttc tgtgtacata aaaaaagata acataggaca gtagaaagga gaatataaaa
    18061 atggaaaaaa taaagattga aagttcagat atttttgaat atatattccc tcatgatatt
    18121 tcttgttcac ctgatggaaa gcatattgct tatattatat caaatatcaa cgaggaaaaa
    18181 gactgctatg aacatgactt atatgtgatg gacatcaaaa cagaaaaaca aatacatatg
    18241 actcaaacaa aagatgtaac atcatttagt tggatttcta atacagaact actttttaca
    18301 tctaaaagaa ataagccaaa agcaggtaca acagattttt acactatttc tatagaagga
    18361 ggagaagcaa aagaagcatt ttctattcca aaagcttgta gcgtacctgt atcacttgga
    18421 aataaattgt ggttattgac aacaaaaaat ccaacggatt ctaaaaaatc agaaccagat
    18481 agggcagtag agggtgtaga ttattggaca tttacagata aaccttttat aagagataga
    18541 gaaaattttt ctcaaagaag acgtgtaaca ttagaattat atcaagaagg tgaaaatata
    18601 acaaaagcca ttacaccaaa attttgtgaa gtagcaggta tagacgtttc ttctgataaa
    18661 aacagaattt tatatactgg tcagatttat gaagattgtg caactccttt ttctggactt
    18721 tgggagtatc atatagacag tggtgaaacc aaagaacttg taccacaagg aaagtaccaa
    18781 ataagtttgg caaaatatat tggcaaagat aaagtaatgt tgcaagcttc aacattagaa
    18841 cgttctatca cacagaatca tgatattttt atacttgatt tgagtactag tgaaataaat
    18901 atgattgcta gtccagatgg tatgtatgct acattactgg atgtagatgc agtatatggt
    18961 ggtggacgta gtaataaagt tataggagat aaatttattg gtgcaagaat ttgcagaact
    19021 atgacagaat ttaatgagtt tgatacaaag acaggtaata tacgtatcat cacaaaagta
    19081 gatgctttta catcttttga tatttacgac aacaccatgt acacagtaat gttgaaagat
    19141 tatgagttag cagaaatata tagcattgat atgactacag gtacaatgaa aaaaatgact
    19201 gctttttcta aaccatattt agatactcat aaggtttcat tacctgaaaa attgacgttt
    19261 gtagcaaaaa ataaagaaga agttgatggt tttgttatac cacctataga tgctaaagaa
    19321 ggcgaaaaat atcctgctgt attgttcatt catggtggac ctaaatgggc atatggctat
    19381 atgtttacac acttgaagca gtgtgtaaca tcaaagggaa tgtatgtgat ttattgtaac
    19441 cctcatggtg gtgacggtta tggtgaaaaa ttcttagaaa tggtagaaag atgggggtat
    19501 gttgactatg agcatcttat ggaatttgta gatacttgta ttgaaaaata tcctgggatt
    19561 gatgcagacc gcttaggggt tgcaggggga agttacggtg gttatatgac aaactggata
    19621 attggccata cagaccgttt caaagcagca gtttctcaaa gaggtattag taacttgatt
    19681 acagcttctt taattattga ctttggggat agaattatga agcagacttg tggagataag
    19741 acgccttgga atcatgagga ggttctttgg aatcattcac ctattaaata tgtgaaaaat
    19801 gttaagacac caacattgtt cttacatagt gatagggatt atagatgttt tatgggggat
    19861 actttccaaa tgtttacagc attaaaacag cttggtgtag atacagaaat gtatttgttc
    19921 catggagata cacatggatt gtctagaaat ggaagaccat ctaatagaat tgcacgagca
    19981 aatgctattg tagattggtt tgaaagatat ttataataag ggggttattc tatgagtgat
    20041 atgttattat ggtttagtgt cgtattagtt ttatttgcta ttggggattt aattgcaagc
    20101 aaaacaaaag caaaagtatc agctgtattt gttacactac ttttattttt gattctattt
    20161 gtcacaaaag caataccagc tgatattatt gaaaaagcag gtatgaccgc agcagctagt
    20221 tggagtgttc caatgattat gtttagtatg ggaacaatgt tgaatgttaa acaatttata
    20281 gacgaatgga gaacagtatt gacagcatgg cttggaattg tagcagttat agtctgtgtc
    20341 tcattatgta ttcctttgtt tggaaaatca acagtattga caagcatacc agttataaat
    20401 ggagctttac ctgctactac tattatgaca caagcagcac tagaaaaagg actgacactt
    20461 gcagcagcta cagcaacagt tgtatttgca attcagaagt ttattggtac accaatagct
    20521 tcaagagcag cgttacaaga ggcaaaccgt cttttagtag aatatcatga agcaaaatca
    20581 aaaggcattg atttagcaaa tgttgatact gataagaaag aagcagagaa tacaggcaca
    20641 aaagtaaaac aagctttctg tgaaaaatac gataaatatt attctacaaa tgtttgtata
    20701 ttttttatag cactattctc ttatctaggg tatgaacttt cagagattat tcatgtaaat
    20761 tattctattg tatgtcttgt tgttggtgtt attgtaacac gtattggtat tgtaccaaaa
    20821 gacattttgg aaaaaggaaa aatcaaggga tttattaaca tggttgtgtt tgcagctgtt
    20881 attccttctt tagcaaaagt ttctttgaca gatttaatta gtctttttgt accaattgtg
    20941 ggtatgtttg cagcttctat cattggtata ttccttatga tgaaggtgtt accaggttgg
    21001 aaaattatcg gttctaaacc tcttgctttt ggagtagggt tttgtcagat gttgggattc
    21061 ccaactacat atttaatttc aaatgaagtg tgtaatgctg ttggagaaac ggaagaagaa
    21121 agagcatatt tgatgtctaa gattatgcct aagctggtag ttggtggtat ggcttgtatg
    21181 atttctattg tagtagctgg tcttatggta ccaatgttgt agataggttt catagttaaa
    21241 aagtggtgtt aatttatagg agaagctaaa aagtagtatt aatttataaa ataattttat
    21301 attagttaat ttgttataag aatattttct ttttatgatt ataattttga ttttataaga
    21361 gagcagattt tttatttgct atgctaatag ttataatttg tttttatttg ctaaaatgca
    21421 actttaattt gatttatgta taatataggg tatttaataa tatttttgaa gaatttttat
    21481 aaaaaattaa aaagaggaga aaaaagggag tgccacaaag tgaacttttt agttctaagg
    21541 cactcttttt tgtacgaaat cgaatatatt ttcaacgttt taaaagtgag aaagagactt
    21601 atctctagtt tgggatagcc aaatttaatt attaaaatta ttttttgttt tatttatcaa
    21661 agagtattcg tgttttagaa gttagtattt tttattttat atatccaagg ttttccgttt
    21721 ctaatgtttt cttttttaaa ataattaggg tattcaatta tagtaaaagg tggatggtat
    21781 tttggaatga tattatttaa agcacagtat tgaatgttga aatcctcaca ttttagagta
    21841 ttatcttttg taatcaaaaa aatcttctat acttatagca aggttacttc tgcaaatatt
    21901 ccatgcatca taatatccaa atttaaattt ttttaatata gagtttacct ctagtctaca
    21961 ctcttgaata actctttcct ctatccaaat tcttataaac tcatcccatt tattactatc
    22021 tatttattac tatctaaatt ttttagtatg tttgtaattg gaaatggatt tattccttta
    22081 tgttttttat aaatagttta taacttaatt tattattaaa caaatcattc atacagaatt
    22141 actttttctt ttagatattc aattcttact tttaataaat atttaataca ttctatctta
    22201 tgtggtttta aaaagtgttt atggctatca ataatctcta atatttcatt catatttatt
    22261 ttgtcatagt aatattttac atcttttata ttgacaaaaa agtgctctaa gtgtatagtg
    22321 tgtatataat aacatcacac tggaggtgat aaaaaatgaa agtgctcatt tctaacacat
    22381 cagataagcc attataccaa caaattaaag agcaaattaa agaagcaata tttactgaag
    22441 aactgaaaga aggggatgca atgccctcaa taagaaattt tgctaatgat ttaaaagtta
    22501 gtattttgac tattagacga gtgtatgaag aacttgaaaa tgaaggtttt cttacacgcc
    22561 aagttggaat aggaacattt gtttcaactg gaaatttaga aatactaaga gactcaaaga
    22621 ggcgtatagt tgaacaaaaa atggcagata tgattaagga tgcaaaagca ctaggaatta
    22681 cacagataga gttacaagaa atgatgggta ttctatatga ggaggattaa tatggaaaat
    22741 attttagaag tttataactt aaataagact tataccaatt tttcattatc taatataagc
    22801 tttgtattac cagaagattg tataactgga tttataggtg ttaatggagc aggaaaaaca
    22861 acaacaattc gttcgatatt ggatgtcgta aagcgtgata gtggaaaaat aaaaatcttt
    22921 ggtaaagatt tcgatggaaa tgagaaggaa ttaaaaaatc gaattggagt tgtatttgat
    22981 gattcatatt tctatgagga gttgtcaatg tcagaaatga aaagtattat tgcaccttca
    23041 tatgataatt ggtgtgaaga agattatcaa caaaatatga agcgttttaa tcttaatcca
    23101 aaacaaaaga ttgatacact ttcaaaagga atgaaaatga aatttgcttt agcattagca
    23161 ttatcgcata aagctgagtt tttaattatg gatgagccta caagtggttt agacccacta
    23221 atccgtagtc agatacttga catactaaca gaatatatga agaaatgtgg tcgtggtgtt
    23281 ttcttttcta ctcatataac atctgattta gacaaaatag cagatatgat tgttatgatt
    23341 gacaatggac gtattatatt agagcgtgaa aaagatactc tattggatga acatagaaaa
    23401 gtaaaagggg atattcaatt tctaaatgat gaaatcaaaa aattattttt aaatttagaa
    23461 attacaggtt atggttttat agggattacc tcaaaaatta atgaagtgca aaaaaatatg
    23521 ccagatattt taatagagcg tcctacaatt gaagatatta tgcttgcata tattgaaagg
    23581 agagagtaat tatgttgatt catttagtta aaaaagatat tctgattgta aaaaaatatg
    23641 tattgttgat attgtttatt gcaataggaa tcccattatt tatattatgg cgtttacctc
    23701 catttgcaca aatattggga tttgtactat caattatatt ttcagaattt atgctgtgcc
    23761 agtatctatt attaaaggag agtcaatatt caaaagcatc tgtattactt tgttcaactc
    23821 cttatcctag acgtggctta gttcaatcta agtatgtttt atttgcaatg gtatttatct
    23881 attgtacatt agtttactgg attgaaaatt tacttattcc acaaatagga acttttgact
    23941 taacatatat tttgattgtt ttattaataa gttctattat ttatggagtt tatatgccta
    24001 ttcaatacaa attaggatat gaaacaacaa aattcttttt cgtgatgata atcatggctt
    24061 catcatttgt attaccatta actatagctc acagcaattt tgaaattcca tttatatatc
    24121 agtatccatc catgatagtg aatattgtat tgttcctttt aagtttaatt atactgttag
    24181 cttcaatgtt tatttctatt aaaattttta gtaataagga gcttgtataa ggtaaggggg
    24241 aattttatat gccacatttg ccagattggg ctgttttact ttgtatctta cttccaatag
    24301 tatataaagc ttgtcagata tttaaaagta aaaaatagag tacatattta tattgccatt
    24361 tttattgagt gaagttagat ggtatgaatt taaaaggtta cttgaaaata aagttacttg
    24421 gtgtgggaga gtaacatcat aatattatag attatatgtt tcttgtgaat caatttgtat
    24481 tttttaatag ataatatcca gtaattttat tttccattga ttattttcaa ttatgagtat
    24541 gattgtgtgt attgtatacc atcttttaag gtgtttttaa aaaattatat cgtcaaaata
    24601 taaatctaag gaatcctata aataaagctt ttcaatttta gaaaactaat aaaaagtagg
    24661 aagttaataa aaagaagctg tctcaaaata gagataagct tctttttcat tgctgaaatg
    24721 acgaaaatat aattgattta atataaaaaa gagtgcttta tgaactattt attttgaaca
    24781 gtagatacac ttgcactcaa tttagttact cctaagcttt atgaactaaa agtttatttt
    24841 gaagcctatt tttctaaata atcatctata tacagtattg cgtttctttt atttattcat
    24901 aatttatttt cttattaaag tttttctata ttactttact tttaatttta tacgaattat
    24961 caaaaataaa atagttatta gaaaaaaata aaagtaattg caaagattgc aattacttac
    25021 ttctatatta attactatac cataaaataa caaaaaaatc aagtcgagta atccttcaac
    25081 ttaagtgata tactaggtat taataatttt taattaataa aatataacta gaggaaaatc
    25141 tacattttct caatttcttt aattaaattg acctctaatt aagtaattat aaggagaaaa
    25201 attatgaatt tagcaaaggg attagatgtt ttaaaaattt catcaaatgt attcggtgaa
    25261 gataaagtta tgtatattcc tgtaatctac acagaagatg atgcaacact tattgacaca
    25321 ggtcttccgg gtcaaggtga tttaataatt gatgctctta ataaaagtaa cacgagcttt
    25381 gataggttaa aaaatataat aattactcat catgatatag accatatagg aaacataaat
    25441 tatctaagag aaaaatctaa gaataatatc aaagtatatg catacaaaag tgaagtcagt
    25501 tatataacag gagaagaaac tccttttaaa ctttatatgt tggaacaaat ggtagataaa
    25561 attgatgata agatgcttag tatgctaaat gttatggtac ttggatttaa atcatcatat
    25621 actaaagtag atgtgtcatt agataaccat gaaaaattga atctaggtga ggaaatagaa
    25681 gttatacata caggaggtca cactagaggt cacatatgtc tttatttaaa agagtctaaa
    25741 gtacttattg ctggagattt gttacaggta gaaaatggag aacttacgcc tgttgatgta
    25801 atgcacagca acaaacaaga gttaaaagat gctattaaaa atataagtaa ttatgatata
    25861 gaaacgatag tttttagtca tggtggatta tatcaaagag acataattgg aacattgaaa
    25921 aacctaatta ttgagtagta ctatatgatt tacaataatt tcttaaatta cttaaaatta
    25981 tatctaaaga tgtagaatca aaattaaata taagtaataa gaattttgct ttaaaattat
    26041 acttaagtgt taagtatgat acgtagtatt acaagtattt tagaatataa ttttttatag
    26101 taattttaag gttctacaat acttcagttg aaaaatattt aacagcatag tataatagga
    26161 aagaaaatat tttaaataaa ctttagtata caaagtgaag aaaaatattt aaattatata
    26221 taatattgta gagtgaggta aaatatttaa gttatatatc ataatacaga gtgaagaaaa
    26281 atatttagat aatgtaccat aatacaaggt gagtaaaaat atttaaagca tgtataataa
    26341 tgcaaagcga agaaaaatat ttaaataatg taccataatg cagagtgagt aaaaatattt
    26401 aaataatgtg ttataataca aagcgaataa gattatttaa agcatgtatt ataatataaa
    26461 gtgagtaaaa atatttaaat catgtatcat aatataagca gagtgaagaa aaatatttaa
    26521 ataatatatc ataatgtaga gtgaggtaaa atatttaagt tatgtatcat aatacaaagt
    26581 aaagaaaatc atttaaatta tatatcataa aaataatatg aaatattgaa cactcataat
    26641 attggaggct ttaatatttt aattgatagg ttacattatt tataacatta aaaatacaat
    26701 ttacataaaa tagacatatg aaaaataaaa aattatataa taattatggg aatgaggttc
    26761 tcccttggat gataatatcc taaactgcca atgagctgat gacttctatg atatcataga
    26821 tgccaccagc tttttttgtt gtttaaatcg ataaaatgga ggtgaattac ttactaaatt
    26881 tttatttttt aaatttgaag aaatatttaa ttaatagaaa aaacagtaga ttatatgtta
    26941 attattttat taagaatggg ttaagagtat acctatatcc tatcaattta aaaaacaatt
    27001 atgatagtca ttacattgac tacagttgat gcaataaaac tttcaaaaaa tcttatgatg
    27061 caaatagaaa ggaattaaaa tgatagaaaa atttaaaact ttaatatgga ttaaaatgat
    27121 aataagaatt aaaagcgttt ataaaacata tggtggacta tttttgttag gactcatagg
    27181 tataccagtt ggtgcaatta taggtcttat agacaccata tttggaacgg ttcttctaaa
    27241 agttacagat attcgagaaa catatccaat gtatctgata ccatttttag cagtagtagg
    27301 agttgttatt gcttattgct attttaaatt tggaggaaaa agtagtaaag gaatgaatct
    27361 aatatttgag gtagggcatg gagaagaaga aattattcct ttaagattgg ttccatttat
    27421 aatatcaggt acatggttaa cccatttatt tggtggtagt gcaggacgag aaggagttgc
    27481 tgttcagatt ggtgcaactt tttcacattg ggtaggtaaa aggttgccta taaaaaatgc
    27541 ttctagtatt tttctagtaa ctggtatagc agctggtttt gcaggattat ttgagacacc
    27601 aatagcagca atactatttg ctatggaggt tttggtagct ggttcactgg agtatcaatc
    27661 gctttttcct gcgtttactg cttcttttac agcaagtgca gtatcaaaaa ctttagggtt
    27721 agagaaattt tcttttgcac tttcttctaa agttgtattt gacttaccaa tattttggaa
    27781 gcttattgtt ttaggaatta tttttggaat ggttggtgga gcatttgcat ggtgcctgaa
    27841 attgtcaaaa agaaaaatag gtaatagatt aaaaaatcct atgataagga ttgctattat
    27901 tggagtatgt cttagtgtat tattcctttt attttataaa ggaagatatt caggtttagg
    27961 gacaaattta attcaaaata gtttttatgg tggagaaatt tattcatttg actggctgtt
    28021 aaagtttata cttacaatac tgactttgtc agcaggtttt caaggaggag aggttacacc
    28081 tttgttttcc attggagcta gtcttggtgt attgttagca ggatttttta atttgccaat
    28141 tgaattagtt gcagcgcttg gctatgctag cgtctttggc agtgctacaa atactttttt
    28201 tgctcctgta tttatagggg cagaagtttt tggatacagc tatttacctt atttctttgt
    28261 agtatgcgct atttcatata tatttaatat ggataaatct atttattcac tacaaaaaat
    28321 ttcaacgaaa caataaataa aacaacataa tgtatgatta taagagaaag aatattagag
    28381 aaaggatagg gtaggaatat gttgacaagt ttagctttga tttttttatt aggaatggcc
    28441 tcgggaggta tttttgagaa gataaaatta cctagcttat tgggaatgtt acttacagga
    28501 atcatattgg gttcatatgt tttaaatttg attgataatt caatactaga tatttcttct
    28561 gaccttagaa agattgcatt gattattata ttaacaaggg ctggattatc tttagatata
    28621 aacgatttga agaaagtggg aagacctgct gtacttatgt gctttattcc agctactttt
    28681 gaaattatcg gaatgatagt tttagcacca aaattactag gcgtttctat attggaagca
    28741 gcagtcatgg gtgcagtagt aggagcagtt tctcccgcaa ttattgtacc taaaatgctt
    28801 aaattaatgg aagaaggtta tggtacagaa aaaagtattc cacagatgct tttagcagga
    28861 acttctatag acgatatttt cgtaattgtg atgtttacag tattcacagg attggcacaa
    28921 ggaaatagta tatcagctat tagtttttta caaattccag tatcaattat attaggtgta
    28981 atagttggag cagtgattgg aatctgttta gcagtatttt ttaagaaggt tcatatgaga
    29041 gattctgcta aaggggtgtt gcttttaagt atctcatttt taatgataag tttggagact
    29101 gctttagagg gtattgtgcc attttctgga ttattagcag ttatgaatat tgggattttc
    29161 cttcagataa aatatcgtgt agttgcaaga agattgtctg taaagtattc aaaactatgg
    29221 gttggtgctg aaattctctt gtttgttttg gtaggggcaa cagtagatat aagttatgca
    29281 tttaaagcag gaattggagc tgtaatttta atatttggag ttcttttatt ccgtatggta
    29341 ggagtattct tctgccttat taagacaaat ttgacaataa aagaaagatt gttctgtatg
    29401 attggctata ttccaaaggc tacagtacag gcagcaatag gaggtgtacc acttgcaatg
    29461 gggatagcat ctggacaact tattttgaca ttagcggttc tcgctatact tataactgca
    29521 cctcttggag cttttggaat tgatgtaact tataaaaaat tattaacttc tgtagaaggt
    29581 aagagtaagt aagaataaaa ataaagatta ttttaagtga taaattatat tttggaaaaa
    29641 actatattat tgagtacaat gttagaaaat catttgagtg attacagaag gtagaagttt
    29701 atatcggatt ttaaggcatg tgatgattat tagaattgat tttgtgaaat tgttattgta
    29761 atatttaatt atatagataa agaagcggag tgataactat gtatttaaaa aaattatcaa
    29821 aattagagtt agttattatg aaatttattt ggaatttaga tataaaaacc aattcatatg
    29881 agattattga ttatatgaaa gaagagcata atttaccaga aaaagtggct ttaaaaattt
    29941 tatcaaaatt atcaaagaaa agattcttat atgttcaaga aacaggcaag tgtatgtatt
    30001 atacagttgc aataaaagaa aagacatatt tagagtttat atcaagaaat gtgcaaaatc
    30061 ttttgaagaa taattttata aggaatttat tagtatcatt tcacgaagag gagctaacag
    30121 aggaaaagat aaagtcgtta gaaaactggg tagtaaattg ggaagaagct tatatataaa
    30181 tgttattatt tttattacaa tttagataat tttggttttg taagctctgc aactattttt
    30241 agatggttgc agagcttatt tttatttttt attcccttaa gcaatactta aaagtaaacg
    30301 catttatatt tactaacttc aatcacttct aatacttaga ttacttttta aaaatatttt
    30361 gatatgtcat ctctatagta atctagaact tgtttctatt ctttatataa agtttttatg
    30421 aatgatatat ataatattcg ttcatttgat taaaaataac a
//
LOCUS       DAMJWO010000049        29756 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.050, whole genome shotgun sequence.
ACCESSION   DAMJWO010000049 DAMJWO010000000
VERSION     DAMJWO010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29756
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.050"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            497..2731
                     /locus_tag="PC366_002263"
     CDS             497..2731
                     /locus_tag="PC366_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2577773.1"
                     /translation="MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNRE
                     FMYQYIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELNNMGATIIESSRELKIRLPNEKEIYSNVTFSIGSTI
                     WNGEPNMTTLILFNQVYSALKKAKSEGKNRYILFDFKDNSFYNKLENDKEFLSEISHV
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     HLFEENCKNIRRWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLAELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKEFEKLLSKENNSEKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEASEHQ
                     KYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMFDIIGYTKEQFFGEMGGNLRAIVHPDDLDFV
                     YKKSLDMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYVDVNKIKN
                     LTKI"
     gene            2762..3607
                     /locus_tag="PC366_002264"
     CDS             2762..3607
                     /locus_tag="PC366_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2577774.1"
                     /translation="MFKEIFLRTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLG
                     MTNIEIAKKLPDNIAKFFTDSHNIQLDWEKNYPYDKISNWILEFKKDTTSYWNVLEYK
                     VDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVL
                     IDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKEKNKKKF
                     DKNDY"
     gene            3847..5580
                     /locus_tag="PC366_002265"
     CDS             3847..5580
                     /locus_tag="PC366_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2577775.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDINEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQDEIPSCDINNDVFETVSEDENRCMVLGRYTVRTKENAQMIL
                     EVNQRCTFEIIEDRGKLLVKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDSTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPD
                     LPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNND
                     ALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSTYE"
     repeat_region   5972..6658
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=5972..6000
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
     gene            complement(7189..7545)
                     /locus_tag="PC366_002266"
     CDS             complement(7189..7545)
                     /locus_tag="PC366_002266"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDF2577776.1"
                     /translation="MVFETFDKVIKLHPNAKPVFHSDRGFQYTSKVFESKLLAQGMIQ
                     SMSRAGRCIDNAPMEGIWGILKVEMYYLRKFDTYEQLVKIIETYIYYYNNFRYQKRLN
                     SMSPLEFRKYLSTEIA"
     gene            7641..8134
                     /locus_tag="PC366_002267"
                     /pseudo
     CDS             7641..8134
                     /locus_tag="PC366_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429361.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            8676..10031
                     /locus_tag="PC366_002268"
     CDS             8676..10031
                     /locus_tag="PC366_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2577777.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATVLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICM
                     AFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKV
                     A"
     gene            complement(10149..10817)
                     /locus_tag="PC366_002269"
     CDS             complement(10149..10817)
                     /locus_tag="PC366_002269"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HDF2577778.1"
                     /translation="MKEVLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTIS
                     EEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAY
                     GDIDIESHRKWDTDRCEAVGMKVDLPLWQESREDLVYEFIDSGFCSVVTKVNLKHLGE
                     EFLGKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGY
                     LEIK"
     gene            complement(10884..11312)
                     /locus_tag="PC366_002270"
     CDS             complement(10884..11312)
                     /locus_tag="PC366_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDF2577779.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            11419..12012
                     /locus_tag="PC366_002271"
     CDS             11419..12012
                     /locus_tag="PC366_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HDF2577780.1"
                     /translation="MNFCYNCSIDFGGDFMYTNFNIDFNNFNKKENATKFMLMGVLLI
                     ILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVL
                     IIACILLFVFPQKIQSIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGIC
                     LILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY"
     gene            12132..13067
                     /locus_tag="PC366_002272"
     CDS             12132..13067
                     /locus_tag="PC366_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HDF2577781.1"
                     /translation="MDKFKYAFDDKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNQIDDTLKARNSYQGCKFV"
     gene            complement(13338..14282)
                     /locus_tag="PC366_002273"
     CDS             complement(13338..14282)
                     /locus_tag="PC366_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDF2577782.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLF
                     FGFIVLGVYSSIRTPQILKISKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVL
                     LYTSPLFLAIFSKVCYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGV
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSC
                     MLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI"
     gene            14598..16028
                     /locus_tag="PC366_002274"
     CDS             14598..16028
                     /locus_tag="PC366_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2577783.1"
                     /translation="MNLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKE
                     DILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGNLE
                     FTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPII
                     NTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESEL
                     FGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGS
                     LKNKKVDIRIISATNADLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKY
                     YFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPN
                     ILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFG
                     SSYKVAKHLEISQSKANRLIRKYTNT"
     gene            16228..16812
                     /locus_tag="PC366_002275"
     CDS             16228..16812
                     /locus_tag="PC366_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HDF2577784.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(16916..17695)
                     /locus_tag="PC366_002276"
     CDS             complement(16916..17695)
                     /locus_tag="PC366_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDF2577785.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRI
                     FKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(17765..19021)
                     /locus_tag="PC366_002277"
     CDS             complement(17765..19021)
                     /locus_tag="PC366_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011591286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HDF2577786.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEREAFKLIKPVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAIEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            19279..20178
                     /locus_tag="PC366_002278"
     CDS             19279..20178
                     /locus_tag="PC366_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDF2577787.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            20202..21650
                     /gene="ddlR"
                     /locus_tag="PC366_002279"
     CDS             20202..21650
                     /gene="ddlR"
                     /locus_tag="PC366_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HDF2577788.1"
                     /translation="MIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKK
                     ANELDIIKSEIPWSSDLISFKSISPDGDLFDMEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLEYMTNKGADISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
     gene            21709..22515
                     /locus_tag="PC366_002280"
     CDS             21709..22515
                     /locus_tag="PC366_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2577789.1"
                     /translation="MNLILGDNMSKKSKRRKINKLKLTIVITVLFLALLSIYEILFSN
                     PNKKGNIKSQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGK
                     SMPTDEPISFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEK
                     IKLIDDYDAVDEKSMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDV
                     TPKISTVYADRSSTKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            22541..24460
                     /locus_tag="PC366_002281"
     CDS             22541..24460
                     /locus_tag="PC366_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_071223118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDF2577790.1"
                     /translation="MNLMTLENISKSYSEKKLLENISLGINEGEKIGLIGVNGTGKST
                     LLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQ
                     EILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIAELSG
                     GQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLD
                     RVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLIRTELAWVKRGAQ
                     ARSTKQKARLQRFDELMNRDSFKPDENLDISVASSRLGNKIIEIHNISKSFEENTVID
                     NLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHM
                     NIDMRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGKLSGGERRRLHL
                     LKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRYFLDRICNKIFA
                     YEGNGKIHIYTGNYSDYLIYREIQGIEFEESKRESVKKDDSTTLKKEKPKNDKKLKFS
                     YNEQREFENIDSDIEKLESKIATLDESTAKFSTDFTKLQEILDEKSKLEKELEYKYER
                     WEYLNNLADEIANNK"
     gene            complement(24702..25049)
                     /locus_tag="PC366_002282"
     CDS             complement(24702..25049)
                     /locus_tag="PC366_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HDF2577791.1"
                     /translation="MSKSNDVLDIVFKITDGLEYEVAENSVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(25036..26964)
                     /locus_tag="PC366_002283"
     CDS             complement(25036..26964)
                     /locus_tag="PC366_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transporter, OPT family"
                     /protein_id="HDF2577792.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFFEGLAVGVGGVLFGIGIAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSAGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVSG
                     MTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGSK
                     NEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGSL
                     PWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEKE
                     KEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVLV
                     VLTTLPIVLSKVKNNEQE"
     gene            complement(27375..29564)
                     /locus_tag="PC366_002284"
     CDS             complement(27375..29564)
                     /locus_tag="PC366_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HDF2577793.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDL
                     EFVCKEEEKVLLEDFNNNQYEVPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELD
                     EVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKLGYELTEKITSSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPI
                     GAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEYNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDMYICAYYVIDEED
                     SGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKKALPE"
BASE COUNT        11150 a         4251 c         3811 g        10544 t
ORIGIN      
        1 atttctatag attaatagtt tataaattta gtaaatgaat atttattata gtctttaaca
       61 aaaaatacaa gaataaactt aattttaata actaaaatta attatgtggt attaaattat
      121 gtataaaaag ttaattatga ataaaataat tatgcctttg aaaaatcatt aaacttaaaa
      181 ttaattataa aaaaactcta ccttactaac tatacagctc acaatctatc tatttatgaa
      241 aaaatatgat ataattgcat tcaaaaagga aatctttcaa tatactataa tttaagcatt
      301 aactaatttt atctaatatt attactaaac taaaaaatat ttgtatttgt agcattggag
      361 caaataactt aatgtatatt cattttaaat acttatttaa aatttagcat ttaaattatt
      421 tacaaattaa catttaaata cttctagcat aaatacagtt gtcatcaaaa tttaaagtat
      481 cttatggagg aataccatgc aaaatcataa ttatataaaa atgttaaata aaaaggtaga
      541 agtattatct aaggaattag atagtagaaa ttttaaatta aaaaccttaa atgaaataga
      601 ttttttttct aaaataccaa acagagaatt tatgtaccaa tatattgatg actgtatttc
      661 gaaaaatata catataggaa tcatgttatt aaatatcgat aactttaaat tatttaatga
      721 tatatatgga tatctagtcg gagaaaattt attaattact ctaactcaaa acctattgca
      781 ctttattcca gaatcaaagg gaatagtcgc ttatttaaaa ggagaaggtt ttttaattgt
      841 acttccaaat gtatcaaata aagagttaaa taatatgggt gcaactatta tagagagctc
      901 ccgagaatta aaaataagac ttcctaatga aaaagaaata tactccaatg ttacatttag
      961 tatcggcagc actatctgga atggtgaacc aaacatgact actttgatac ttttcaacca
     1021 agtatatagt gctttaaaaa aggctaaaag tgaaggcaaa aatagataca ttctatttga
     1081 ttttaaagat aatagttttt acaataaatt agaaaatgat aaggagttct tatcagaaat
     1141 atcacatgtt ctacaaacta aacaaattga agtattttac caaccacttt ataatataaa
     1201 aaataatact atagttggat gtgaggcact tgcaagatgg agacacccta ttaaaggact
     1261 tcttactcca gataaattta ttcctttatt tgaacagttt ggtctgataa cggaattaga
     1321 tttgcattta tttgaagaga actgtaaaaa tataagaaga tggattgata acaatgatgt
     1381 ttttgttcca atttgttgta acttttctcg tcttcatttt tttaacccta attttccaag
     1441 tatgctaaaa ggtattactg aaaagtacag cgtctctaca tcaaatttta gcattgaaat
     1501 aacagaaaat atattaatag aaaatacaaa tacaattatt caacaactag ctgaacttcg
     1561 ttcttatggt ttttctgtat caatggacga ttttggttct ggatattcat cttttggtat
     1621 gttgcaaaat ctaccttttg atataatcaa aattgatagg atatttttat ctcataattt
     1681 aaatgatttt aaaaatacaa ccattttgta ctctataata aacattgcaa gagctcttgg
     1741 gatgcttaca gtatgtgaag gtgttgaaac agaacaacat gtagaattta ttaaaagtat
     1801 aaattgtgat atcgcccaag gttattatta tgcaaaaccc atggagtgca aagaatttga
     1861 aaaattacta tctaaagaga ataattcaga gaaaatgttt ataaaatatt ctgatatagg
     1921 aaaatcttta atagagaaga tatttgatgg attttttatt atgcaagata tgaaaaaact
     1981 aagagctaat gtcactgaag acattcaatg gtttgatttt tacaacaaaa ctgaaattac
     2041 atcttttcct aaagtaatag aacattttga aaaacatatt aaaggtaaaa aattttctat
     2101 tctttacaaa agtataaccc cacataatac tgaatcagat tcattattaa ttagtggaga
     2161 agccgtttta tcagatgaag cttctgaaca tcaaaaatat agcaatttct actttagtgc
     2221 aaattgtata atttcagaaa ataaattact cttagcaaaa ttacatttgg atttaattaa
     2281 aactgctggc tatataaatg aatttgaatc atattcaata cctaaaatga caaatacaca
     2341 tcttgatgaa agtaatattt tatcacaatt ttattcaatg ttgcctgtag gtataattcg
     2401 ctacgattta tttggtgata tgattattac ttatatgaat gaagaaatgt ttgacattat
     2461 aggttataca aaagaacagt tttttggtga gatgggcgga aatttaagag caattgttca
     2521 tccagatgat ttagactttg tttataaaaa aagtttggat atgattgaca caaataaaat
     2581 tgaaccattt ttatatagat tcataaaacg agatggtcaa attgtcacag ttatgtatac
     2641 acaatgtaac ctttctgcaa ttgatggaag gtcgattgcc caaggtatgt atgtagatgt
     2701 aaataaaata aaaaatttaa caaaaatcta gtacaaagta ttttattttg gagaaattaa
     2761 tatgtttaaa gaaatttttt taagaacttt tccaggattt ctaattataa gagattctaa
     2821 ctacagaatt atatttataa atgataattt aaaaaattta attaaaagtt atatgcaaga
     2881 taatccactt ggaatgacta atatagaaat agctaagaaa ctccctgata atattgctaa
     2941 attttttacg gattctcaca atattcaatt agattgggaa aaaaattatc cttatgataa
     3001 aatttcaaat tggattttag agtttaaaaa agatactaca agctattgga atgttttaga
     3061 atacaaagta gatgttgatg aaaaaaccta cataattact atggccaatg atataacaaa
     3121 actctatgaa gaaaataaga gaaatcttca ctactcaatt actgacccat taactggagc
     3181 atataataga aaatatttaa atgatagatt tgacatattt ataggagatt atattgtact
     3241 aattgactta gataatttca aaatgataaa tgactatgaa ggtcataatg taggagacaa
     3301 gattttatgt gattttgttt cacttttaaa taaagaatta ataaattcta cttctattat
     3361 aagattagga ggagatgaat ttattgttat attctctagt gatgttgaca aaaattatgt
     3421 ttattcacaa ctagaagcct taagagaaaa ttttttaaaa gtattctcta aatataagta
     3481 tctttcattt agttatggtg ttgatacagt aaaaagaaat ttaaaattga caatagttga
     3541 attggataaa aaaatgtata aaaacaagga gaaaaacaag aaaaaatttg ataaaaatga
     3601 ttattaacat tgttatttta aaataaatta aaattatctt tcttttttta aacttgtaca
     3661 ttagtttata aatatgtatc tatacaagat attgacatta agtactgaag catatattgt
     3721 ttcagttctt ttttgttaaa attaacttat ttgacaaaga tatcatagtt taacaaagct
     3781 tttaatttaa atatattgat gtataatata attaaaatat aatagcaaaa agaaaggagg
     3841 aatatcatga gcatactcct aaaaaaagca cccaaattag caaaacatat tataacaagt
     3901 ttttatataa atcgagatat caatgaagta ttaaaatacc tttgtgaaaa tgttacatgg
     3961 attggaccag gagaacagga atttctcact tcttttaatg aaataaaaaa ttatttttat
     4021 gcaggtcaag atgaaattcc ttcttgtgat ataaataatg atgtatttga aactgtaagt
     4081 gaagatgaga atagatgtat ggtattagga agatatactg ttcgaactaa agaaaatgct
     4141 caaatgattt tagaggtaaa tcaacgttgt acatttgaga taattgagga tagaggaaaa
     4201 ttattagtaa agcacatgca catatcaaac ccttatggtg aaatgcaact tgatgaatac
     4261 tttcccacta aaattggaac tcaaagttat gattatttgc aaagattact aaaggaaaaa
     4321 acagaagtta ttgaaatgat tacaaataat atcaatggtg gcttaaaagg tagcaatgat
     4381 gatagtacat actcattttt ctatgtcaat gagggattgc ccaaaatatt aggatacaca
     4441 tatgatgagt tcatggaaat gagtggtggt tcagcagtgg gtgctgtata tccaccagac
     4501 ttacctaaag cactagaaga ttgtgaacga tgttttgcaa aaggacctac atattcatct
     4561 gaatatagaa tccgaaaaaa agatggaaca ttaatgtggg tattagattc tggaatgaaa
     4621 tcgttaaata gtgatggcat agtaaaaatt aatagtatta ttactgacat aacccaacta
     4681 aaaaacatag aatctgaact aaaattagaa agagagcgat atcgtattgc tttgcaaaat
     4741 attacagata tcatgtttga gtatgatatt gaaaacgata cccttataaa atatcaacgt
     4801 gtagaaattg acaaaaaaat tgaattagaa aattttgaaa caaaaaatta ctccaaacta
     4861 ttagaatctg gtaaaattat tcaccttgat gatattggaa aactactaga agtacttcat
     4921 ggaaatcttc gtgaaacaat tgagataaga caagtaaatt cattaactaa aaatgaatgg
     4981 agatggattc gtgttcaatg ttcagttata tatgatagtg accataaccc tatcaaaaca
     5041 ataggcgttt taaaagacat aactgaagat aaatctaaat tagaaagctt aattaatcag
     5101 gctcaacgtg acccactaac acaattatat aatcaaagag tatcacaaaa tcttattgaa
     5161 gagtatctat gtagttctga ttccaaaaat aatgatgctc tattagttat tgatattgat
     5221 gattttaaaa ctgtaaatga tacttttggg catttagagg gaaatgaagt tttagttgct
     5281 gtatcaaaaa tactattaca taacacacat gataaagaca tagttgctcg aattggtgga
     5341 gatgaattta caatatttat aaaatcatta acaaaggatt taataataaa aattactaat
     5401 gatattttaa atgatgcaag taaaataaaa gtaaaggaca atcataaaat aacattaagt
     5461 attggtattg ccttcactga tgattcaact aaattatata aagatttatt ttctaaagct
     5521 gataaagctc tttatctatc aaaagcagat ggcaaaaatt gttatagtac atacgaatga
     5581 taaagctatt tatacgacca agaatgaacc tttagattta atttcatagt ctaacaatca
     5641 aagagttgaa gctaatctta tagctagtca actagttcct agaaaaaatt tagacaatat
     5701 atttattgat actgctcatt tttctaaaga tcaaatttat ataaaaaatt aaacttttat
     5761 gtacatacag atactaatga taaacattta gcattagtat cttctatctt aaaataaaat
     5821 gataatttat ctatataaaa aagtgctttg ttgacagagt tcactttttt atataggtac
     5881 agaatttaag tataaataca tgttttattc tatacatttt agttaatgta aaatttcttg
     5941 attgtactct ctaacttttc aacattatac tatttacata ccacttagtt aatataaaac
     6001 caaaagttgg agaaatagaa gtgccattca cattcgaatt tacataccac ttagttaata
     6061 taaaacactt taataattct acctttacta gtgctaaagt aatttacata ccacttagtt
     6121 aatataaaac caggaacata tggcaaacta taaggaaaac ctgcaaattt acataccact
     6181 tagttaatat aaaaccctct gtgactccat attttttcat aatatataat tcatttacat
     6241 accacttagt taatataaaa catagaagtt gttgcatata actacattga caagttatta
     6301 tttacatacc acttagttaa tataaaactt ttctactttt ttaatcattt aatcacctgc
     6361 ttaaaaattt acataccact tagttaatat aaaacttttg atattctaaa gaagtgacaa
     6421 tgatgtgaca caaatttaca taccacttag ttaatataaa actattatgt agtcatatat
     6481 ttcaaactct aatttcgtat ttacatacca cttagttaat ataaaaccca tttgacccat
     6541 gcatattgac ttccaccttc cttatttaca taccacttag ttaatataaa actttacaat
     6601 atagacgtac atatacttct gaaaaacctc tttccatacc acttagttaa tataaaactt
     6661 taccccaaaa taaactgggc attttcaata cttacacatg tgcaactctc ttaaatttgc
     6721 agtgaaccat gagtagtgca aatgataaag tttatcatat accctcaaca ccttatattt
     6781 caagcattaa gccctacttt gtaacaaata tcgctcactg caaaactatt tacattttta
     6841 ttatatcata aatatattat ttttgaatat ctgtaccaat ttgtggtata ataaaaacaa
     6901 gaagaactac aatctattta gacgtagagt gaagttcaaa tactaatgtt tattcttttt
     6961 gaacttgatt tttagttcaa aactaaagtc actcctgctg aactataccc actgttttat
     7021 acagttaaaa catgtaaaag tagttataaa gtactagtgt aactcattag tacttttttt
     7081 attatattca tataattaat atctatattt taaagtttac tatctaaaaa agagcacgtc
     7141 aaataaaacc ctagatattt aaattttttt agagctactt aaaataaatt atgctatctc
     7201 tgtacttaaa tatttcctaa attcaagtgg agacatagaa tttaatctct tttgatatct
     7261 aaaattatta tagtaatata tataagtctc tattatttta actaattgtt catatgtatc
     7321 aaatttcctt aaatagtaca tttccacctt taaaattccc caaattcctt ccataggagc
     7381 attgtcaata caacgaccag ctcttgacat actttgtatc ataccttgtg ctaaaagttt
     7441 cgattcaaac accttactag tatactgaaa acctctatca ctatgaaaaa caggttttgc
     7501 atttggatgt agttttatta ctttatcaaa agtttcgaat accaagttat tattattcga
     7561 ttttccaata acatatgaaa ttaatagata taacgccttc tattttacag tcttatataa
     7621 ataacatata caatgagcac atgttaaatt caataaaaaa ccaagtcgat tttataaaat
     7681 cagtattgaa agaatcttat agattaaaag aaatatcaga aaatatttgt gattttgtta
     7741 caaccccaat caaaaaaaat agttcaactt ctaagtttta tacaaagcaa gaaactcaat
     7801 tattattaga aaaatcaaaa aatattccta taggtatacc aatttttttg atactaactc
     7861 ttggattacg ttttggtgaa gctgtatcac ttatatggtc agatgtagac cttgataaaa
     7921 aatctcacat gtaaatcaaa cattagttta tgtatacaat aaaataatct tcaaagaccc
     7981 taaaatccct agatccaaaa gaaaattatt tgctcctgat gaacttataa gtttgcttaa
     8041 agggcaaaaa ttaaaacaaa ataagttaaa attacagggt atattgaaaa atgaatttga
     8101 tttgatatgc ttaaataaaa gattcaaccc gtgagttcaa ccaacttttg ttgttcattt
     8161 taaaaaacta ttaagagata ataatcctag agatataaaa gtacatgaat taatacatgc
     8221 aaatgcgact ttgatattac tttcaggtac taacataaaa gctatttata aaatattagt
     8281 acatgcagat ataaaaatag ctatgaataa atattcgata ttctcactta ttagatgaaa
     8341 tggataaaga aacatctgaa aatataagca aaatactatt caaataatgt tcagttttat
     8401 gtcaattaaa tgtcactcaa agtgcttttt ttccatttgt cagttaaatg tcacttaaag
     8461 tacctttttc ctatttgtca gttaaatgtc agtaatatat aaataagata tatttataag
     8521 acccttaaaa tcactattat ttaataaaat ttataattat atactatttg ctgttgacat
     8581 tggtattata ccatagttta tcatttatat tagaaataaa attattaatt aatagtttcg
     8641 taattttata atagatttac agggagtgat aataaatgga tacaaaaata tctataaacg
     8701 aaaacatgag tctaggtaaa agatttttta aatacctagc accatctgta gttgcaatgt
     8761 gggttttctc actatataca atggttgatg gaatatttgt aagtaaagga gttggagaat
     8821 tggctttagc tgctgtcaat atatcaatgc cttttattaa ttttatattt gcagtttctc
     8881 tattattttc aactggtgca tctaccataa ttgcaatcta tctggggaaa aaagatatta
     8941 aatctgctaa cgaagtcttt tcatttaact tagtatcaat aattatatta tcaataatta
     9001 tattagctat aacttttttt aatttagata gattagcact atttttagga gctacagaat
     9061 ctacaattgg tatggttaaa gattatttag gaataataat attttttaac ggattcttta
     9121 tagtgtctta ttctttagaa gttataataa aaactgatgg ctttccaata ttagctactg
     9181 ttggtgtaat aatatctgct cttacaaaca tcatacttga ttacttgttt gtaattgaat
     9241 ttggatgggg tgtaaaaggt gctggtattg caactgtttt gtctcaagtc ttttctacta
     9301 ttttcttctt aatacatttt ttaagaaaaa actctacttt gaatttttca aaatttagaa
     9361 ttgattttaa gacacttaga aaaattgtat ttataggttt tcctgattca actactgaat
     9421 taagttgtgg tatagttgtt ttacttttta acttaagtct tactaaatat attggagaaa
     9481 atgctcttat ttattatagt gtcataaatt atataaatac attagtactt atgactatga
     9541 tgggtataac tcaaggtatg caaccactta ctagctttta ttatggtgca ggaaatatag
     9601 ataatgtaaa aaaattatta aaaatgggga taaaagccac aataatagca tcagttgctg
     9661 tatttgcaat ttgtatggct ttttcaggac caatagtctc tttatttata cacccagaag
     9721 aaacaatgct attcaatgaa ggagttcgtg tatttaaaat attctctata tctttcttat
     9781 tggtaggaat taatgtaata atttctggat tctttgtatc agtagaaaaa ccatcaattt
     9841 ctactgttat atctcttggt agagggcttg taatagttgt tttaagtcta atttcaatga
     9901 tactaatatt tggtggacaa ggaatatgga tgactactat tgtttctgag tttatatgtc
     9961 ttattttatc attagttttt ctaaaaaaga atttttctac attagactct aatctaaata
    10021 aggttgctta gatgataaga gtagcaatat atgaaaatat ctaaataaaa aatacctatt
    10081 atacaatctt gcaaatatta gacctttgca aaaattagga ttatataata ggtattttat
    10141 ttatgtaatt attttatttc taaatatcca tagccatctt ttattaaagt tccttttact
    10201 tcatattcta caggtttttt aaatattgga ccatctacga caaatgtatg atactctcca
    10261 tgttctccac atgggtctgc accagcattt tttatcttct ccacaagttc tctagttaat
    10321 ttttttccta aaaattcctc tcctaagtgc tttaagttta cttttgttac aacactacaa
    10381 aatccactgt ctataaattc atatactaaa tcctctctac tctcttgcca taatggtaaa
    10441 tctactttca taccaactgc ttcacatcta tcagtatccc attttctatg actttctata
    10501 tctatatctc catatgcaca tatcgttgct cccatgtttt tagcttttat taaagccctc
    10561 tcaaagctct cttcatatcc ttctacacca cactcagcaa ctaataaagg taatcctata
    10621 ttgctactta cttgcttaag catattatat tctaaattat gtgtccatga ctttccatgt
    10681 tcttcactta tagttgtcaa gagtgccaca ggcttatatc cttttttcaa cattcgattt
    10741 aatgctaata tactatcctt accaccacta aatgacatta caaatttttc atcagccaat
    10801 tttaacacct ctttcatcta actttgtttt attaacataa ttataccaaa tttttgagtt
    10861 gcatagcaaa ttatattaaa ttgttaattc actataaaga atgtccctaa tattaaaagt
    10921 ataaccccta tgtatttgta taaatgcatt gtttcttgtc ccaaaattac gctatcaata
    10981 aaaaatccaa ctaaaacttg ggatacaagt gttaatataa gtgtatttga tactcctaaa
    11041 tttggaattg cctttactgt aaaatatatt attaaacctc caaatactcc tcctaataac
    11101 aacttataat taaaaccatt tatagatact agacacttta agtcacctgt aactattata
    11161 cttgccaaaa aaaatattgc tcctacagtt aaacttataa aggtggccac taatgctgtt
    11221 gtactttttc ctagttctcc atttataaaa gcttcaagag ctgtagaacc acctgctaat
    11281 aatgcaaata ttattgccca taattttgtc atggacaaac ctccttctat ataattctat
    11341 taatagaagt ctatgataca acctattaat taattactaa gtatagttta atttttatac
    11401 actaggcttt atttggatat gaatttctgt tataattgtt ctatcgattt tggaggtgat
    11461 tttatgtaca caaattttaa tatcgatttt aataacttta ataaaaaaga aaatgctact
    11521 aaatttatgt taatgggagt attgctcatt atcttaggat tattatgcct tacatttaag
    11581 acattaggta taaaattaat ttcttggact tttggtattg cacttttatt ctttgcatat
    11641 ttaaatttaa aaaatattaa tgaactaaaa agatatgcta ctaaagaaga aattaaaccc
    11701 tctattaata tccaatgggt tctaataatt gcatgtatat tactttttgt atttcctcaa
    11761 aaaatacaaa gcatattttc attattttta gggttttatt taatctttaa tcaactagta
    11821 gcacttgtaa atagtaagaa taatccttat tctaaattta caacttggaa tatagttaag
    11881 attctatttg gtatatgcct tatattatct ccactttttt tatctagatt tatagtatcg
    11941 ataatgtctt ttttcataat attatttgga ctagttctat ttttctctgg aaatacagcg
    12001 agaaaatatt aattattttc tcgctgtatt tttatattac ttaaaataga atttgtttaa
    12061 gttatctatt tgtggtaata tgttttttgt acaagctcag cgtacaattt tattagaaat
    12121 aggtgatttt tttggataaa tttaaatatg cttttgatga taaaagatat catacttgga
    12181 attactatct tagaaatact tttggagaaa aagtttttaa ggtatctata aatgcaggat
    12241 ttacctgccc aaacattgat ggaagtcttg gttatggcgg atgtacctac tgtagcaaag
    12301 aaggctcagg tgattttgct ggaaacccta aagataatct tatcagtcaa ttttataata
    12361 taaaagaaat gatgttaaaa aaatggcctc atgcaaagta tattggctac tttcaagcct
    12421 atacaaatac gtatgctcct cttgaagttt taaaagaaaa atatgagact atattagaac
    12481 ttgaagatgt cataggtctt tcaatatcca caagacctga ctgtttgcca gatgatgttg
    12541 tagaatactt atctgaacta aataaaagaa ccaatttatg ggttgaactt ggacttcaaa
    12601 caattcatga ttctacatct aaaattataa atagaggtca tgattataaa acatttgttg
    12661 aaggtgttga aaaattaaag tctaaaaata taaaggttgt cgtacacatt ataaatggtc
    12721 ttcctggtga agattataat atgatgatgg aaacagcaaa ggcagttggt aaaatgggtg
    12781 tagacggtat aaaaatccat ctattgcatg ttataaaaga tactcctatg gaaaagatgt
    12841 tacaaaatgg tatgttaact cttatggaac aagatgaata tatcaatctt gtctgtgacc
    12901 aattagaaat acttcctgaa actatgataa tccatagact cactggtgat ggtaagaggg
    12961 atgaactagt aggtcctata tggagcctaa aaaaatggga aattttaaat caaattgatg
    13021 atactttaaa ggctagaaat tcttatcagg gctgtaagtt tgtttaatac aaaataataa
    13081 ctatagaaat ggttatataa atatagtcct ttctatagtt atttagtatt tacaaaacaa
    13141 aatattaatt tgtacattta tacaatatat aataaaaaat agatagtcta aactgtatct
    13201 acttatattt tatttgtact gtccacttta ttctataaaa tttataaata gttatttttt
    13261 aataccaaat ataatttggt ataatttttg ttggattcta aaatgtatac caataaatcc
    13321 tttttaagta tataattcta aatactttca gttttttcaa tctgctttaa cttgttggat
    13381 ttataaaata ttcttatttc atcataagaa agattaagtg ctactactgc agatattaac
    13441 atcaacatca ctccaaataa cttccctaag gaaaaacttt ctcctaatat agtgcaacca
    13501 attattactg aaccaactaa ctctactgat gccacaacac ctgcaactga caactctaca
    13561 cctttagata tacctgctgc ataaaaaata tatgcaagtg cagctggaac aatgcctaac
    13621 attagcatac aagataaaac atctaaatcc ttagcataat ttaagatttc ccaaggtctc
    13681 gaagaaggaa tcataaatat agctccaaat aagaaactgt atactaatat tgttgaactt
    13741 gaaaattcct ttaaagcatt tttactaata gttggcataa gtgcatatgc tattgctgat
    13801 aataccccaa gtaaaagtcc aaaagcgttt aaaccttgaa aatccaaacg tccaccagtc
    13861 actgccataa ttgcaccaat aaaacaaaga ataagtgaaa ataatttgct tctagtaata
    13921 ttttctttat aacatacttt tgaaaatatt gctaaaaaca gtggtgatgt atatagtaaa
    13981 actgctgcaa ttgatacacc tgcaatgtca attgctttaa aataacataa attaaacatt
    14041 gcctgacata taattcctat tattactgaa tatataattc cttttttgct tatctttaag
    14101 atttgtggtg tccttataga tgaatatacg cctaaaacta taaatccaaa aaacaatctt
    14161 gtaaatgcta cttgttctga tgtcagtcca tttcccatta aaaactttcc aaataatcca
    14221 agtgtagccc ataataaccc tgctattgct ataaatacat accctttact tttttctccc
    14281 attttaaatt cccttctatt tttatttagt caatttacac tcttcttttt aagcaaaaat
    14341 tatgccatct taaaccaata tatatcgact ctaaaaccct agtctttcca ataatactaa
    14401 taagttttca attttcttat atttattttt cgcttacttt aagttgattt agacttattt
    14461 taattgtaaa atgagttata tataacttat ttaaagttaa aatagactga aacttatata
    14521 aatatcaaat tttaagtata ttaatcaatt aaacctattt taatatatca ttaaaaattt
    14581 aggaggaaaa tataaaaatg aatttagatt tggaatttta tcaaaaaata ttagaagctt
    14641 cccatgatga aatatgtgtt tctgatgata aaggaataat aatatattgt aataaagcat
    14701 ttgaagaaaa ttatggtcta aaaaaagaag atattttagg aaaaaatgtt tcttttttag
    14761 aagactctgg atattcaaca aaaagcccca taccaattgt attaaaaaca aagactaaat
    14821 tttcactgga acaagatact caaacaggga aaaagcttat cataactgct acccctatat
    14881 ttgatgaaaa tggaaactta gaatttactg ttgaaaattg tagagatata actgaactta
    14941 ataatataaa aaataaactt gaagacacaa aaaagcaagt aaaaaaatat aaatctgagg
    15001 tagaaacact atacagaact gcacttagaa ttgaagatac tgtaattatg gacggaatag
    15061 tgatgagacc aatcataaac acagtaaatc atgtttctaa aacggatgta agtgtacttt
    15121 tattgggtga atctggaaca ggaaaaagct cacttgctag atatatacac cacaacagca
    15181 atagatctaa tggcccattt ataacaataa attgtgcaac tatatctcca caacttcttg
    15241 aatctgaact ttttggatat acttcaggtg cttttacagg tgcaagtact aaaggtaaag
    15301 ttgggctcgt agaattagct aatggaggaa ctcttttttt agatgaaata ggagatatac
    15361 cacaaaatct acaggcaaaa tttttgcaat taatacagga tagaactttt actccagttg
    15421 ggagcttaaa aaataaaaag gttgatataa gaattatatc tgctacaaat gctgatttag
    15481 tttcaaaagt aaaagaaaaa aagtttagag aagatttata ctatagatta aatgttatag
    15541 aaataaaatt gcctcctctt agagaaagaa gggataatct agtggaaatt ataaaatatt
    15601 attttaatag gtactcaagt gacttcaacc taaataaaac tatttctaaa gaagctatgg
    15661 atgctattgc aaattataga ttcccaggca atataagaga attacaaaat ataattcaaa
    15721 aaatcttgct tacttgtaca gataatcata taacaataga tgacttacca aacattctta
    15781 caaaaaatat acatattacc aataatggaa ataaaacaca tatatcccaa attaataagg
    15841 ttattatatc tgactcaaaa tctactaatt ataaaaataa aaattttgac accttaatta
    15901 aagagtatga aaaaaatata attttggatg cttatgaaaa atttggtagt tcttataaag
    15961 tagccaaaca ccttgaaatc tcacagtcta aagccaatag gttaattaga aagtatacta
    16021 atacttaatt ttaaatttga taaataaaaa cttaacacta tttacatatt gtaaatttgg
    16081 ccatttactg ttattatgaa tatggttgaa attatttaaa taaatactgt tgacttagtt
    16141 tcatatattt accattaaac ttttatcata aatatcatat cataataata tatttaataa
    16201 gtctaataaa ctatacgagg tgtaaatatg ttaatgaata cccattttat tatggcaaaa
    16261 tcaatacttg ataatataga tgaaaataaa acattcttta taagcgaaaa aaattttata
    16321 tatggcaata taaagcctga tgctttttct aaatataaat taaaaaaaca ttatttagat
    16381 gagtcattta atatgattgt ttctaaaata aactatctat gcagtcttaa tatagatagt
    16441 ctttctaaat acttttcagt aagtagactt agtcaggaac taggagtcat atgtcatttt
    16501 ttatgtgatt ttttctgtgt agctcacagt gaacgttggg aatttaagca tagcttaaat
    16561 aaacatgtta cttatgaaag agaacttgga gcatttgcaa aagatgttga tttatctaaa
    16621 attaaatgtg gtactataaa tagtagtttt gagaagtttt ttactaaact ttatagtgat
    16681 tacaaaaaga aaactgatta tatgaatgat ttaaaatttt cagcttatac ttgtaatagt
    16741 gtcataaatt atatacttga ctctatttta tctaatacaa taaaatcata tcatatagca
    16801 aattgcggtt aacttaagaa tttttaaatt tatataaact tataattgaa tataattaaa
    16861 atgactgctc tatagaatat aattttatac ttctctagga cagtcatttt ttatactaac
    16921 tatttatctc cattataaca tctatggcac tttttacact atctactaca taatttgcac
    16981 tttgctttac atcttccctt gccttagaca ttgcaaaact atatttaaat ccttctaaca
    17041 tgcaaatatc atttggagaa tccccaatag tagcaacttc atctggactt acatttaacg
    17101 tttttattac atgctctata cttcctcttt ttgacacact tttaggaact atatttaaag
    17161 tatatgttcc agaaaaatat atttctaata cttcactaaa ctcacttttt agataaagtt
    17221 ctattctgga taactcttcc aaattttcag aacatacgcc tatatttcct ataagattat
    17281 caaaactact tcttttttca aaatctgggt caactataaa gtcactagaa taatgtctaa
    17341 aagcagtggt atcactaccc acaattacat cacccttata tttaaaataa agttgtgcat
    17401 cacttgattc aaatctatca atgacttttt ttactaaatt atcatctatc gttcttttaa
    17461 aaattacatt ataatcttta tcatatataa atgaaccatt ttcacataca taatatccat
    17521 tcatatctaa actatctttg ataatattat gtgcttgttt aaaaattcta cctgtagcaa
    17581 cattaaactg tactcccttt ttttctattt cttcaattgc tactatatct tcttttgtta
    17641 tggttccatt ttcatataga gttccatcta aatcacaaaa tatatgtttt atcataaatt
    17701 aaaagcctcc aaaaacaatt ttatattata gtaacacttc aaatatatcc aatatcataa
    17761 caacttaaag cttttctaat tgtattctca attcattaag taaatctcta gtagctctta
    17821 atcttatctt tcttctatcc ccattaaata tatttttctt tactattgtt tttccattta
    17881 tatatattgc agtataaact agtcccacag gcttctcttt ggttcctcca ccaggtccag
    17941 ctactccagt tgtggatata cctatattag ctttaagtcc tttagcaacg ccctcagcca
    18001 tttctatagc tgtttgctca cttactgctc caaactcttc caaagtttct ctttttactc
    18061 ctaatctttt cattttagaa tcattagaat atgttacaca tccttcaaga aatacagaag
    18121 atattcctgg atagtttata agagatgaag aaaccaaacc tccagtacaa gattcagcca
    18181 ctgctattgt tagatttttt tctacaagta acttagaaac agcatcttct aaagcagtct
    18241 ccccttcaga tatggaaata tctccttcag tatatacata tttaccaact ctacttttta
    18301 ttttttcttc tactggtttt attaatttaa aagcttctct ttcattttca gcctttgcag
    18361 ttattcttat tgtaacttct aattcttttg catataaagc aactgttgga ttagtctgct
    18421 cattaattat atcgagaatt tctaattcta gatttgactc acctattcca tataatctta
    18481 aagtcttaga tactagcatt tcatttgtga attgttgtaa gtaaggtttg acactctcat
    18541 taaacatagc tttcatttct cttggaggtc caggcaatac tattataaat ttaccatctt
    18601 tttttaaaat tgcccctgga gctgtaccat tattattttt tagtactata gcatcttttg
    18661 gaaagtacac ttgtttcata ttattttcgg ccattttttt tcctgtttta acaaagaaag
    18721 attccaaaac ctctagtgaa ggtttatgta gttctaattt ctgaccaaag tattctgcag
    18781 cagtttcttt tgtcatatca tcaccagttg gcccaagacc acctgtagta attacaaaat
    18841 cacttctctt taagctttca tcaaaacatt ctaaaagtct ttgtttgtta tctccaacag
    18901 tactctgatg gtatacttct attcccaatg atgcaagttc tttagctaaa aattgagaat
    18961 ttgtatttac tatatctccc aataatattt ctgttcctac acttattatt tcagctttca
    19021 aaatttatca ctccttgatt tatagccatt aagactagtc ttaagttcat aacaataatt
    19081 ttagcaaaaa taataacata aataaagtta aaaaatcatt taaacatatc tttaaactag
    19141 attattattc taaaaccaca cataatataa acttcgtata tagtggtact ttcatcctca
    19201 actgttaatt catataatta agtatgtaaa taaaaagttt actttaaaat aataaaaatt
    19261 aaaataggag tgtataatat gaaaatagca gttataatgg gtggaatatc atcagagaga
    19321 gaagtttctt taaattcagg aaaagagata tataataacc ttgataaaaa taaatatgaa
    19381 gttgtaaaag taataataga tgataaaaaa gatatattta caaagatacc agaagatata
    19441 gattttgcaa tacttgcttt acatggaaaa tttggtgaag atggatgtat tcaatcaata
    19501 cttgagacta tggatatacc atactctgga tgtggacctc tttgcagtgg gatgtgtatg
    19561 gataaaaata taactaaaaa aatgcttaga gattcaaacc tacctactgc tccatgggtt
    19621 ttagtaaaat cagttgatga aatcgactat gatgaaatag ataatatagg ttatccagta
    19681 tttataaaac caaactcagg aggttcaagt gtagccacat tctttattca ttctaaggat
    19741 gaagttgaag aagcagttag aaaaggtctg gaagttgacg aatttgtaat gattgaaaaa
    19801 tatataccag gtggagaata tacttcattc atattaaatg gagaagtgtt ccctacaata
    19861 tctataaaat ctgattcagg attctttgat tatgaagcta aatactcagt tgaaaaaggt
    19921 gcaaaggaag aagttgttta cttagatgaa gaacttcaaa aaagagtaaa cgaaatttct
    19981 gagacttgtt ggaaaatttt taattgcaaa gcatatgtaa gagttgatat gattataagt
    20041 gaaggtattc catatgttct tgaactaaat actcttcctg gaatgactca aactagttta
    20101 attcctagaa gtgctgctgc tagaggtatt aagtacagtg aactattaga taaacttata
    20161 gaatactctt taaattagat gaaataattt gaggtggtaa tttgatattt tcaaatctaa
    20221 aactaaatga taatgaacca atttatatac aacttaaaaa ttatataagt gatatgatat
    20281 caaaaggact aattccagac aatagtaagc tcccttctac aagggagctt agtcagcttt
    20341 tacaagttag ccgaaattct gtagttttaa cttatgaaga attaaaatca gaaggattaa
    20401 tctactctat ttcaggaaaa ggtacatttg ttaaatcaaa gaataagtct tcaaatacta
    20461 catggtcatt aaactgggat tgtttagaga atacatactc taaaaaagcc aatgaattgg
    20521 acattataaa aagtgaaatt ccttggagct ctgacctgat ttcctttaaa agtatttctc
    20581 cagatggaga tttattcgac atggaagaat taaaaaaatc ctttttaaat agaatttcac
    20641 tagaaggaca taaattactc aactatggat atgcacaagg ttataagccc cttattgact
    20701 atttactaga atatatgaca aacaagggtg ctgatataag taataaagat atactaataa
    20761 caaatggatt cacagaaggc tttgatatta ttatgtcatc ttttacccaa gaaaaagact
    20821 acataatatg tgaaaatcct actcataata ctgctataaa aattatgaaa tctcataacc
    20881 tcaatatctt aggtgtagat ataaatgaag atggtttgga cttcaatatg ctagaagaca
    20941 atttagttaa gtataaaaat aaaataaagt ttgcatacat tacaccctct tatcacaatc
    21001 ctacaggaat tgtaatgact cctgaaaata ggtacaaatt ctataatctt atgaaaaaat
    21061 acaatatagc aattatagaa gatggattta atgaagaatt actctacaat agttctcata
    21121 tatttcctat ctgttcccta gataatatga ataatggggt cgtatatatt ggtagttttt
    21181 caaaaatttt atttcctgga atgagaattg gatggatatt tgcagataaa aaagtaatca
    21241 ataaactaga aagtgtaaaa aggtgcagaa acatacatgt atccttttta gaccaaggaa
    21301 ttttatttga ttatttaagt aatggaggtt ttgaaaaata cattaaaaaa atacgtaaat
    21361 tctatgggga caaatttaac tttgcatata aatgtataaa aaaatatata aaaacagaat
    21421 atatcttggg tgatggaggt ttgcatatat ttataaaact aaaaaatata gatactagag
    21481 ttttattaga aaaatgttat gaaaaaaatg ttatatttat gcctggagat ttatttttta
    21541 cagataactc tggttttgat actttaagac tcggattttc taggttgtct tttgaagaca
    21601 ttgaaattgg aataaaaata attggagaaa ctataaatga aatgttctag gttaactaaa
    21661 tattgttagc ctagtttatt tttatgaggt ataatatata tagtttatat gaatctaata
    21721 ctgggggata atatgagtaa aaagtcaaaa cgaagaaaaa ttaataaatt aaaattaacg
    21781 attgtaataa ctgtattatt tcttgcttta ttatctatat atgagatact gttctctaat
    21841 cccaacaaaa aaggtaatat aaagagtcaa gaaactatgc agaataaaaa taatacaaca
    21901 gatgattcta aaaataatca aagctctacc aaaaagcagg aagataataa tatcaagcct
    21961 actttttcat attcttcaat accagataat ataaaaaata aaatgattgg taaatctatg
    22021 cctactgatg aacctataag ctttgatagt ctatcttatt taaaacttac atattatgga
    22081 tttgatgaaa aaactcatca aggagaaatg atagtaaaca gtgaactagc tccagaagta
    22141 gtggatattt ttaaggaatt atacgaaaaa aaatatccaa ttgaaaaaat taaattaata
    22201 gatgactatg atgctgtaga tgaaaaatct atgtctgata ataatacctc atcattttgt
    22261 tatagaacta tagctggtac aaatgtagtt tcaaatcatg gtaaaggacg tgctatagat
    22321 ataaacccat tacagaatcc tcaagtttct ggaaatgatg ttacacctaa aataagtaca
    22381 gtttatgctg ataggtctag cacaaaattt ggaatgataa aaaaaggtga tgattgttat
    22441 aatgcttttg taagcagagg ttggagttgg ggtggctatt ggaaaaaccc agattatcaa
    22501 cattttgaaa aataatagat tagaaataaa ggtgaattat atgaatttaa tgacattgga
    22561 aaatataagt aaaagctatt ctgaaaaaaa attactagaa aatatatctc ttggaataaa
    22621 tgagggggaa aaaataggac ttattggtgt aaatggtact ggtaaatcta ccttactcaa
    22681 aattattgca ggagttgaag aaagtgagac tggtaatata acaaaaacta atggtattag
    22741 gatagaatat ctacctcaaa atccaactta caatgaaaat tcaactgtac ttgaacaagt
    22801 atttaatgga acttctgaag aattaaagct acttggtgaa tatcaagaaa tcctagaaaa
    22861 acttaattca aactttacag aggaattaaa taaaaaatta ttatcagtac acgaaaaaat
    22921 agatgcctta aatctttggg atttagaaag tgaagctaag tcagtactta caaagcttgg
    22981 tataaatgac tttaatcaaa aaatagcaga actttctggt gggcaaagaa agagagtctc
    23041 tctggcatca gcccttatta caccttgtga gtttttgata ctagatgagc ctacaaacca
    23101 tctagacaat gatactatag attggcttga ggaatatctt aattcaagaa aaggctcatt
    23161 gcttatgata actcatgata gatacttttt agaccgtgtt acaaatagaa ttattgaact
    23221 ggacaagggt agattattca gttatgatgg gaattattca atatttttgg aaaagaaaat
    23281 ggaaagactt tcgctagaag caagtattga agataaaaga caaaatttaa taagaacaga
    23341 gcttgcgtgg gtaaaacgag gagctcaggc tcgtagcact aaacaaaaag ctcgtttaca
    23401 aagatttgat gaacttatga atagagattc ttttaaacct gatgaaaatc tcgatatatc
    23461 tgttgcatca agtagacttg gaaataaaat aatagaaata cacaatatat ctaaatcatt
    23521 tgaagaaaat actgttatag ataatttaga atacacttta actcgtacag atagaattgg
    23581 tataataggc aaaaatggta tgggtaaatc tacccttata aatatactta atggagaaat
    23641 agagcctgat agtggatata tttcaattgg agaaacagtt aaaataggtt gtttttctca
    23701 agacgactct catatgaata ttgatatgag ggctatagac tatgtaaaag aagctagtga
    23761 ctatatagaa acttcagatg gtactaggat tacagcttct caaatgtgtg aaagattcct
    23821 ttttaatggt actatgcaat atactttgat aggtaaatta tctggtggtg aaagaagaag
    23881 actacatctt cttaaaatcc ttatgacagc tcctaatgtg cttcttttag atgaacctac
    23941 aaatgattta gatattgaaa cgcttaaaat attagaagaa tacctagacg aatttaaagg
    24001 tgtagtagtt acagtatcac atgatagata tttcttagat agaatttgta ataaaatatt
    24061 tgcatatgaa ggtaatggaa aaattcatat ctatacaggt aattacagtg attatcttat
    24121 ttatagagag attcaaggaa ttgaatttga agaatctaaa agggaatcag ttaaaaaaga
    24181 tgactctact accctaaaaa aagaaaaacc taaaaatgat aaaaagctta agttctcata
    24241 taatgaacaa agggagtttg aaaatattga ctctgatata gaaaaactcg aatctaaaat
    24301 tgcaacactt gatgaaagta ctgcaaaatt ttcaactgat tttactaaac ttcaagaaat
    24361 tttagatgag aaatctaaac tagaaaagga acttgaatac aaatatgaaa gatgggaata
    24421 tttaaataat ctagctgatg aaatagctaa taataagtga tattaaaata atcttaagtt
    24481 taataagttt tgctttaaat ctatacttta taaatatttt aaaggtagtg tctcaaaatg
    24541 aactttttag ttttatgaga cactcttttt tatgagaaat caaatatgtt ttcatcattt
    24601 caacaataca aaagaggctt atctctattt tgagacagcc tctttcataa ttaccttcta
    24661 atttatatgc tttaatatat ctataataat tcttattata tctatatatc cagtctttca
    24721 atatagtgac aattaacttc aatatgattt aaaaatacta acaacctttc ataaagtgga
    24781 tgagattctt ctccatattt agcttctagg ttcttgccta tttctctaac agtcctttga
    24841 ccatcaattt gtaaaaaaac aaaactggaa tattcatcta gttctatttt tttgtattta
    24901 ggtattctag cttttaactt tctaaaaaac ttttgaattt tatggtcctg tttttcaagt
    24961 atagtaacaa cactattttc agctacttca tattcaagtc catcagtaat tttaaataca
    25021 atatctaaaa catcattact cttgctcatt attttttact ttagataaaa caataggtaa
    25081 tgttgtaagc acaactaaaa ctactaataa agcaattgcc attgaatttg ttgcagcaaa
    25141 tccacttggt acctttggag ttacaactcc agttacttgt aatattatac ctattaaacc
    25201 aatgatagaa ccaccagcaa caagaccaga agataaactt ataccattag aaactttaac
    25261 ttctttttct ttttcagttt tagatactaa ttcaacaaat aaacgaatta atgctccaac
    25321 taatattata gaagttgttg caattggtaa atagaatcct atagctatag tcattattgg
    25381 taaatttaat gcatatagaa ctattgccat aaatactcca acaataatca taacccaagg
    25441 taaactacct gacataatac cagaagttaa tgttgacatt aagtttgctt gtggtaatgc
    25501 aaattgtaca ttatcaccag ttgctctaag ttggtcagaa agtaataaaa ttactcctac
    25561 aacaactata acaccaacta tacttgcaat tgtaaagtaa cgttgcattt cgtttttgct
    25621 accaccaata atataagtta ctttttgaga ttgagtataa cctccagcta tagcaatagc
    25681 aacaactata aatgaaccaa ataaaagtaa tgatttatta gcttctaaat cagtccatcc
    25741 cattataaca aacactaatg ttacaataac tagagaagct atagtcatac cagaaactgg
    25801 aagatttgat gttccaattg ttcctgttaa acgaccagct actatgacaa ataataaaga
    25861 taataaaaga gatatgatag ctccaataat tgccataaca atgttaccag aaattaagaa
    25921 tgctgctaaa aatccaataa ctactccacc taataaaagt atcatttgta tagatgaacc
    25981 ttcttctcct tctccagcac ttgatttagc tttaagtgtt tcttttatag aagcgattat
    26041 agttggtata agttttattg caccaataat acctccacaa agcatcatac cagcacctat
    26101 atattttaca taactactag atattgctcc gacatccatt tggttaagag gcattgcagg
    26161 attattccat accatagctc catctttagc catatctgta aagtatccta ttaaaggtgc
    26221 tataccaaag tttgataaaa tacttcctgc aaacattgtt aaagaaactt caagccctac
    26281 tataaatcca attcctaaaa gtagaggatt tacttcaata tcaaatttcc atttgtagaa
    26341 tttgcttcct acaagactca ttacattgtt tgctacattt aagaatgaac cagttaatac
    26401 agtaataaat ccacttatta caaatccaat tcccatgtac ttaattgaat ctccaccagc
    26461 ctctgaagca acaagtgtct cagatatagc cattgattct ggatacataa gtttaccatg
    26521 ttcttcaact attagatagt tgtgaactat agcagcaatt cctataccaa ataaaactcc
    26581 accaactcca acagctaggc cttcaaagaa tgtaatttgg cttccaatta atataactgc
    26641 tggtaatacg aaaataaatc cacttgcaac agattctcca ccacttgaca tcccttggat
    26701 taagttttta ccaagaatac cctttgaacg agcaaatgct ccaacaaaag cagaacctat
    26761 tatagctcct ggaatacctg cagcaactgt aagaccggct ttcattccag agtaagttgt
    26821 agatgcggca aaaatggcag ctaaaataat accgataatc agtacagcta catttccacc
    26881 ggttctggac ttatctgtga tatatggaac gtaatctttt ccactaacct caccataagc
    26941 acccttaggt aattttttgt tcataaaatt ttcacccctt ttcaatttgt atatattata
    27001 acatatatac atataaaact taacttttta ttattttaca aatagcgagt caaaactact
    27061 aaaatttaac cctatattat taatttctac ttttagatat ttttatgcta attttctttt
    27121 tatttttcaa ttctactaaa aactattaag atataaaata aaaaaaattt ttaatgtaaa
    27181 attaattttg taaaaaaaat gctttaaaac acggaaaagt ataaaaaata caataatcat
    27241 tcttataaat aaattttcac catagtaaat atatacagaa aattcttttt tttacatcaa
    27301 ttgatttcct cagaaaaata ggtgtcataa agaaatgtat ggaatcactt tacaacacct
    27361 gtcataataa aaaatcactc tggtagtgct tttttattta cttttcctat tggtgtaact
    27421 ggtattttat ctatcctcat tattattgtt ggaatcatat atggaggtag atgctcattt
    27481 aaatattctc taatggttct ttcatttatc ttaccactat cttcctcatc aattacataa
    27541 tatgcacata tatacatatc cccgtcatca tttgttctcg atatacaaac aacactttta
    27601 atttctgtaa tattatttat tatattttca atctcatata gctctatcct aaactcatca
    27661 atttttactt gattgtccat ccttccaata taatctaaat ttccatcatc taaccatctt
    27721 actaaatcac cagttctata cattaactta ttatattcac aagttttgta aggattctct
    27781 acaaatactt gctctgttag ccctttttta tttaaatatc ctcttgatat ttgaatgcct
    27841 gatagacata gctctcctgg tgctccaatt ggacatagtt tgttcttttt atctaataca
    27901 tatgcataag tattaaatat aggttttcct attggtattt ttccatattc tctgtccaca
    27961 tgaaaagaag tcgatacaac agtaaattcg gttggtccat actcattata tagttcataa
    28021 ttacgctttc tatatccttt taatctttct cctccagtct gtacaactct aagtgaatta
    28081 ttattgcaat tttgtataaa taaccttgca aatgctgttg gcaatgctag tatagttatg
    28141 tcattttcct cacagtattc atttactgta tattcatcaa atttagcttc ttcaggcata
    28201 atatctattg atgcacctac aagcaaataa gggaatagtt gtttcattac agcatcaaaa
    28261 ctgaaactta agtatatacc acatatatca ttttctgtag cgcttataga ttttacgcta
    28321 taataacaca tatttactaa actcttatgt tctatagcta tggtctttgg cctaccagtt
    28381 gaccctgaag tagatatcgt atatgcacaa tttgatgatg ttattttttc agttaattca
    28441 tatccaagct taaacatttc ttcatcattt atatcgagta ctatggtatt ctcatttaca
    28501 accttacttt tgagttcatc tgtagttatc actacttttg cattactatc ttcaagaagg
    28561 taattcaatc tttcttctgg attactcgtg tctattggaa aaaatgctcc ccctgatttc
    28621 ataatcccta ttgctgtaat aattatgtta atatctcttg gtaacattac agctactatg
    28681 tcttcacttt ccactcctat atgatttaaa taacctgcaa gtttatcagt tacctcatcc
    28741 aattctttat atgttaactt tctattttca tccctagcag ctatattact aggtgttacc
    28801 ttaacttgct ccctaaataa atcaacataa cttttatcat agggtacttc atattgatta
    28861 ttattaaagt cttccaataa tactttttct tcttccttac atacaaattc taaatcttct
    28921 attaaaatat cattatcttc tattatttgc tctattatat aatcaaattg atttaaaatt
    28981 cttctaatag tttctctttt atatatagat ggtttatact ttatttttat tttaagtgcc
    29041 ctcttagtat atactattac agataaatca tatccttttt tttctatgtc ataatcatat
    29101 gataaatcaa aacttttagc tataaatatt gtgtttataa gcttagtatt tagatgattt
    29161 ttattctcta tatctgataa caaatagtat ccatactcta aagacctgct ccactgcctt
    29221 tttagcttcc ttacaacatc tataaatttt tcactttgtc taactcttac tcttattgga
    29281 attatattca ttgttttacc aaaaactaca tcatcttcat atatatactt ttgaagtata
    29341 aggccatata tagtttctat gatagagtct atgctaatat tgttcacttt agaatattga
    29401 attaaccttt catgtttctc aatattcatc ttaaaaacct catctactac ttcatcagaa
    29461 caatctttat aaaaaaaatc atttggaatt tttgctatat tcgtataatc atctaacaaa
    29521 tccatccaat aattcatagc tcgttctaaa ttaacttcat acatatcaaa attccccctt
    29581 actactaagt ctatagaaaa aattcttttg gaattttatt ttcacaatat ataaatatat
    29641 taataataca tatgcaagct ctaaaaacat gagcttgcat aaaattacac ttattatgac
    29701 tactaaattc gtaatattta caatgtttaa aatatattat aacacatata tgattt
//
LOCUS       DAMJWO010000050        29441 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.051, whole genome shotgun sequence.
ACCESSION   DAMJWO010000050 DAMJWO010000000
VERSION     DAMJWO010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29441
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.051"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            87..908
                     /locus_tag="PC366_002285"
     CDS             87..908
                     /locus_tag="PC366_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HDF2577794.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKEVPFAGILLKNNEDIESMQRHL"
     gene            929..2125
                     /locus_tag="PC366_002286"
     CDS             929..2125
                     /locus_tag="PC366_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDF2577795.1"
                     /translation="MFIEFFYLLRSRGLNISLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSINYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMLSR"
     gene            2291..5689
                     /locus_tag="PC366_002287"
     CDS             2291..5689
                     /locus_tag="PC366_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HDF2577796.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNTLLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVVTVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIISFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGFGFLNLSDIDLYTLSSINQDLETEDIGYRSINKSFKDEENRYKFIDGYNIQI
                     HNDLENEIYISKNASRQSGILSGIDVVHTPEFEEELAGLGMSQNFFKISDSLGVLSIN
                     NTDYSSIQRVLQLPSIIRTVSTTKMTLLGEINRGTFGGVVATEEMGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDIN
                     RAIAENDPSLSQDEVGQGTMLSGICSGLGNVNSEYAGIAEDSELIIIKLGKIDGFYNS
                     AMLFAASQYAYKKAFELRRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGN
                     EGNTQTHTSGIIPHVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKS
                     VGISNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRELLKSGTRFREVDPFYTINYPAIQDDLITVGAYNTINGSLWQSSSRG
                     PTIEDRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            5699..7372
                     /locus_tag="PC366_002288"
     CDS             5699..7372
                     /locus_tag="PC366_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HDF2577797.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPVDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSQLNIAINRND
                     GSLSQDNIGTGTLVSGILAGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     ISGEYDIYLPNKNLIAPDTRFLDPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            7646..7840
                     /locus_tag="PC366_002289"
     CDS             7646..7840
                     /locus_tag="PC366_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HDF2577798.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     misc_binding    8009..8242
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8319..9716
                     /gene="asnS"
                     /locus_tag="PC366_002290"
     CDS             8319..9716
                     /gene="asnS"
                     /locus_tag="PC366_002290"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HDF2577799.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     gene            complement(9889..11064)
                     /locus_tag="PC366_002291"
     CDS             complement(9889..11064)
                     /locus_tag="PC366_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2577800.1"
                     /translation="MNLEKIKKFFGFPLDKKHKENVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFATPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKFGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCDETDAKLKSECLRKII
                     ESCNFERDDVPLKCVTVSIGVYTKKIEKAITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            11483..12847
                     /locus_tag="PC366_002292"
     CDS             11483..12847
                     /locus_tag="PC366_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2577801.1"
                     /translation="MGEKKINNMNYSHNNYSKKTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEIASLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLINPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIRTFIL
                     GYVLVLVILLVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIRPIIVFSIYY
                     AFLMGILALFSTFILDSNINFFNTTNYGTTLIMQFKVLQAIVISFVYSFVISLIGYKL
                     NSAD"
     gene            12869..13360
                     /locus_tag="PC366_002293"
     CDS             12869..13360
                     /locus_tag="PC366_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2577802.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EKKAKIFLEMGILTYQKIREDSINDNSFDKFCDELLELDKLIYEKNMEINEMEMAESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIICGYCESEIDTEAEFCPCCGRKIIM
                     DLE"
     gene            13633..14304
                     /locus_tag="PC366_002294"
     CDS             13633..14304
                     /locus_tag="PC366_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDF2577803.1"
                     /translation="MLDKVKGRLIVSCQALENEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMERLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            14389..15255
                     /locus_tag="PC366_002295"
     CDS             14389..15255
                     /locus_tag="PC366_002295"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HDF2577804.1"
                     /translation="MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGS
                     TGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYDAISA
                     VTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENEKIIGV
                     KFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFE
                     LTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEM
                     KSRAKEIYRKYF"
     gene            15288..16790
                     /locus_tag="PC366_002296"
     CDS             15288..16790
                     /locus_tag="PC366_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HDF2577805.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSVVLAGLTGIPVNVLIVV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFIGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YRMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            16920..17372
                     /locus_tag="PC366_002297"
     CDS             16920..17372
                     /locus_tag="PC366_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HDF2577806.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEKGDFL
                     PLDGKNNGYMELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            17532..18335
                     /locus_tag="PC366_002298"
     CDS             17532..18335
                     /locus_tag="PC366_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577807.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESIIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NTGCTTLSKHYNIENKYVIWIQGESDAKYGSDALYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACNECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNMLGEDLCKNIYKYHITKEKSVLSDTIDLSEARKYICELEKISKRFV"
     gene            18393..19280
                     /locus_tag="PC366_002299"
     CDS             18393..19280
                     /locus_tag="PC366_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF2577808.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGFIIDKSSLDTEAKEKGGEGIL
                     AKIKDIVKKYIEENEISGICISTAGMVDPVEGKILFALEELIPNYKGMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEVWLGAGRGATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNINGSSFQELASTSSLIKKVAKIKNLNEKDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            19299..20147
                     /locus_tag="PC366_002300"
     CDS             19299..20147
                     /locus_tag="PC366_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2577809.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            20210..20899
                     /locus_tag="PC366_002301"
     CDS             20210..20899
                     /locus_tag="PC366_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF2577810.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKAKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITFDSSKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
     gene            21289..22296
                     /gene="asrA"
                     /locus_tag="PC366_002302"
     CDS             21289..22296
                     /gene="asrA"
                     /locus_tag="PC366_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HDF2577811.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKEVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEIIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVISKEE
                     V"
     gene            22297..23088
                     /gene="asrB"
                     /locus_tag="PC366_002303"
     CDS             22297..23088
                     /gene="asrB"
                     /locus_tag="PC366_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HDF2577812.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCNTKGVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYSGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            23101..24072
                     /gene="asrC"
                     /locus_tag="PC366_002304"
     CDS             23101..24072
                     /gene="asrC"
                     /locus_tag="PC366_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HDF2577813.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAVVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            24129..24905
                     /locus_tag="PC366_002305"
     CDS             24129..24905
                     /locus_tag="PC366_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDF2577814.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGLIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPTI
                     STVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            25176..27194
                     /locus_tag="PC366_002306"
     CDS             25176..27194
                     /locus_tag="PC366_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDF2577815.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYVFSYDLK
                     RAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAVGAVIIMIAQFVMNRNRMKNVGDKEL
                     ISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERISLIMERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEINYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKV
                     KSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIPSLIEDRLMLINAI
                     YKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIVNTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEAA"
     gene            27409..28266
                     /locus_tag="PC366_002307"
     CDS             27409..28266
                     /locus_tag="PC366_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2577816.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
     gene            28363..29232
                     /locus_tag="PC366_002308"
     CDS             28363..29232
                     /locus_tag="PC366_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2577817.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
BASE COUNT        11678 a         2983 c         5270 g         9510 t
ORIGIN      
        1 aatgtattgt attattattt ttatatcaaa aatagtaata aagtctatat acatttagaa
       61 aatactgttt aaaaggagta ggatttatga taaaaaaaga gatatctaac tttagaggaa
      121 gtagtgatta tgtagtatca ccagaattga tggcatcagt taatgttgct attgctcttg
      181 aaaagccact tttgattaag ggcgaacctg gaacaggtaa aactatgcta gcacaagcaa
      241 tttcaaatga attaaaaaaa gatttagtaa tttggaatat aaaatcaact acaaaagcac
      301 aagaagggct ttatgtatat gatactgttc aaagacttta tgatagccaa tttggaggag
      361 aaggtgtaga tgatattagc aagtacataa aatatggtaa actaggagag gcctttagct
      421 caaatcaaca agtaattctt ttaatagatg aaatagataa ggcggattta gaatttccaa
      481 atgacttgct ttgggaattg gataaaatgg agttttacat aaatgagaca aaagaaactg
      541 taagagctaa acaaagacca atagttatta taacttcaaa tgcggaaaaa gaacttccag
      601 atgctttttt aagaagatgt atatttcatt atatagaatt tcctgataga gacatgatgg
      661 aagaaatagt taaagtacat tttgataaag tagaagaaca cctattggaa caagtaatga
      721 ctacttttta ttggattaga agtttaaagg acatacaaaa aaagcctagt acatcagagt
      781 taatagactg gatacaagca ttaactttga gtggaatgcc tattgaaaaa atagaaaaag
      841 aagttccttt tgcaggaata ctacttaaga ataatgagga tattgaatct atgcaaagac
      901 acttatagtt aataggagct ggataattat gtttattgaa tttttttatt tattgaggtc
      961 aagaggatta aatatatctt taaatgaatg gatgacttta attgaagcat tggataaagg
     1021 gctgtgctat tcaaactttt caaattttta ctatctttgc aggatgattt taataaaaag
     1081 tgaaagtgat tttgataagt ttgatgcagt gtttttggag tattttaaag gtatagaaca
     1141 ccaagaagaa attccagaag agattatgaa ttggcttaaa aaaccagata tagatttaga
     1201 agagtttgaa agattggaac aaaatccaaa tataaatctt gataaattaa gagctaaatt
     1261 ggaggaacga ataaaagaac aagactctcc tcataatggt ggtaattatt ggataggcac
     1321 aggaggcact tccgagttag gacattcagg aaaagggcaa actggtatac gtataggtgg
     1381 aaattctact tatggtagag ctgttcttga agttgcagga gaaagaaaat acagagattt
     1441 tagagatgat gaagttttaa atatgcgtca atttcaagtt gcactaaaga gacttcgtca
     1501 attttctact agaatagatg ctccaaagac agagcttgat ttggataaga ctattgaaga
     1561 gacttgtaat aatgcaggat atttaaagtt attttttgag aagccaagaa aaaatacagt
     1621 gaagctttta ttgcttatgg attcaggtgg ttcaatgagg gggtatagca ctttatgtaa
     1681 tacattattt cagtctgtaa gtaaatcaaa tcattttaaa gatgtaaaga tatattattt
     1741 ccataactgt atttatgata gattatttac aacacctgaa tgttggttaa gtaaatctat
     1801 taatactgaa tggatattaa aaaatataga taaaaactat aaagttataa ttgttggaga
     1861 tgcttctatg tcgccttctg agttacttca tattggtggt aactatcgtg gtccatataa
     1921 ttacacacct ggtatagaat ggcttaaaag gtttaagaga aagtacagta aaattgtatg
     1981 gatgaatcca gaacttagag atggatggga ttcaattaat tattggtacc aaactcaaag
     2041 aatgatacaa agtgaattta atatgtttcc actgactgta aaaggtcttg aaaaagcatt
     2101 gaaaaattta atgctttcaa gataaagtaa atataaatga tggtatgatt tattcaaaat
     2161 tgtaccatca ttatttattt tttaatatat ctattataaa ttgtataact gaaacttaaa
     2221 aaattatata gtctaataca ttttagactt acacaaaaca tatacattaa taataatttt
     2281 agaagtcgag gtgattataa taaattatga attaattgta aaatacaatg gagatatatt
     2341 gagattagaa gaagaattag gtgtatcagt agagatactt aattcatcat atgcaataat
     2401 aacatcaagt aatgaagaag atgtaaatac acttttaact tatccagaaa ttgaatttat
     2461 agaaaagcct tttatattac agactcagga tgtgcaaagt ttttcaagta caggaataac
     2521 ggggtttaaa aatagaactg gtttaactgg aaagggaact ataattggta taattgattc
     2581 gggaatagat tatactctac ctgtgtttag agatagtgat gggaggtcta agatattata
     2641 ttattgggac caatctattc aaggaaatcc accagaaggt tttagagaag gaacattata
     2701 tactaatgaa gatataaata atgcaataga tggaagtatg tatataccta tttcaacaac
     2761 tagtttacat gggacacatg ttgcaggtat ttgtgcaact attgcaagtg atgccagaat
     2821 aatagtggtt agagttggaa atatacagac cgatattttt tcgagaagta cagagtttat
     2881 gagggcaatt aaatttattt tagatagggc attagaatta agaatgcctg ttacattaaa
     2941 tataagttat ggaagtaatg aaggttcaca tagaggaaca tctttatttg aacaatatat
     3001 agatgatatg tgtttatttt ggaaaaacaa tatagttgta gcagctggaa ataatgcaga
     3061 taaaggaggt cataaaagga ttaggcttca aaataatatt acagaagaag ttgagtttat
     3121 agttggggaa ggagagcgta tattaaacat aaatatatgg ccagattttg ttgatgattt
     3181 tagtgtacat ttggtaaacc catcaaacaa tcaaacacaa gcaatctctc taacttcagg
     3241 tgagataaga aatactttgg gtgaaactag aataactggt tatttttacc ctatagcacc
     3301 gtactctctt acaagaagag ttactctaca attaagttca aatacacaga taactcctgg
     3361 gttatggaaa attgtatttg aaccaataga tatagtaact ggtaatgtaa atatatattt
     3421 gccaacttct gaaggactaa atagaaatac tagatttctg attcctactc aagagcttac
     3481 tgtaacagtt cctggaacag caagtagagt tgtaacagta ggtagtttta attcaagaac
     3541 agacatagta tctatatttt ctggtgaagg agatacacaa ttaggtgttt ttaaacctga
     3601 tttattagct ccaggtgaag atataatatc ttttttacca ggaggtacaa gtggagcatt
     3661 aactggaact agcatggcta cacctcatgt tacaggggtt tgttcattgt ttatggaatg
     3721 gggaattgta aatggaaatg atttattttt gtattcacag aaattaaggg cattactttt
     3781 aaagggagca aggagattaa gtaatcaatc ttatccaaat aattcatcag gatttggttt
     3841 tttaaattta tcagatatag atttgtacac tctatctagt ataaatcaag atttagaaac
     3901 ggaggatatt ggatatagaa gtattaataa gtcatttaaa gatgaggaaa ataggtataa
     3961 gtttatagat ggttataata tacaaataca taatgactta gagaatgaaa tttatataag
     4021 taaaaatgca agtagacaat caggaatact atcaggaata gatgtagtcc atactcccga
     4081 atttgaagaa gaactagctg ggttaggtat gagtcaaaat ttttttaaga taagtgattc
     4141 attaggtgta ctatctataa ataatacaga ctatagtagt atacaacgag ttttgcaact
     4201 tccttcaatc ataagaactg tatcgactac aaagatgaca ttacttggag aaattaatcg
     4261 aggtactttt ggaggtgtag ttgcaacaga agaaatgggc gtaaatttct ttaaaaataa
     4321 tcctaatatt aatataacag gaagagggac tctaatatca attgcagata caggaataga
     4381 ctatctacat ccagatttta tttatccaga tggtacttca aaaatagtat atttatggga
     4441 ccaaacaaaa gaaggaactc cacctgatgg tttttatatt gggacagaat atacacgaga
     4501 agatataaat cgagctatcg cagaaaatga ccctagtcta tctcaggatg aagttggtca
     4561 aggaactatg ttgagtggta tatgctcagg gcttggaaat gtaaatagtg aatatgcagg
     4621 tatagcagaa gattctgagc taataataat aaaactcggt aagatagatg gtttttataa
     4681 tagtgcaatg ttgtttgctg catctcagta tgcatataaa aaagcttttg aacttagaag
     4741 accactagtt ataaatatgt ctttaggtac cagtagcttg gcaggtttaa ccaataggag
     4801 caatagtgaa aaagcattct ttactagagg gttatgtata acagcaggag caggaaatga
     4861 gggcaataca cagacacata catctggaat aataccacat gttggaggtt ctgttgaagt
     4921 tgaattagag ttaaatgaag acgaggaaga attatcatta gaactttggt taaatagacc
     4981 agataaagct gatgtaataa tagtatctcc cactggtgaa gaaagtaaaa gtgttggaat
     5041 ttcaaattat aataaagtaa caggtttatt tgatttagag gggactgaat attctataac
     5101 gtatatatac ccaacaactt tttctgggca gcaatttact aatgttactt taaagaatgc
     5161 aaaaagaggt gtatggaaga ttcgattagt aggggtttat attataacag gaagatataa
     5221 cttatacctt ccaaatagag aacttttaaa aagtggaact agatttagag aggtagaccc
     5281 tttttacact ataaattatc ctgctattca agatgattta ataactgtag gagcctacaa
     5341 tactattaat ggtagtttat ggcaaagttc atcaagagga ccaactattg aagacaggtt
     5401 aaaaccagat atagtagcac caggtgtcaa tataatagct gcttatcctg ggaacacgta
     5461 tgcaactata actggtacag cagcagcaag tgcacatgca gctggtgctg ctgcaatgta
     5521 tttccaatat acttttgttg atggtagata tccaaaccaa gcatatgtgc aaaaaataaa
     5581 aacttttatg caagctggtg ctagaaaaga ttcaaacaca gtatatccaa atacaaattc
     5641 tggatatggg cttttggatg ttagaggaat gtttgatgtt ttaagatagg agggatttat
     5701 ggaaaaatct tattgtataa tttatcaagg tgatatagaa tctgccctac aagaaaatgg
     5761 aataaatagg tatatggttt taaatagtca gcttgcagta atatatgtac ctgtagattt
     5821 tgatgaaact attttaaata atataataca agttgcttgg tgggaagaat ctgaaccaat
     5881 gagcagtcta attgaaataa ctaataatgt aaataatgga gaaaccatta caacagcagc
     5941 tgaaactgat tatatttatg aaaatccata taatgatata acaggaagag gaattttatt
     6001 agcagttata gattctggta tagattattt gcatcctgat tttataaatg atgatggaac
     6061 tagtaaagtt ctatatttat gggaccaaga agcaaataca aatccacctc cagaaggttt
     6121 tatttttgga agtgaattta caagaagtca gttaaatata gccataaata gaaatgatgg
     6181 aagtttgagt caagataata taggtactgg aactttagtt tctggtatat tagctggaaa
     6241 tggaaggata aattcgcagt atagaggtat tactacagaa tcagacttaa tagtagttaa
     6301 attaaaatca tatacagata cttattatgc tggaaggata aattatagtg tttcagattt
     6361 tttagcagct ataacgtatg ttactaatat agcaagaaca gaaaataaac cactaataat
     6421 aaatttgact attggagtta agtcaagtgc tgtagcaact acttcaatat tagatacttt
     6481 taatatattg agtagtgctg gtgtggtagt agtgagtggt gcaggaaatc aagggaatac
     6541 agatattcat tattctggca gatttagcag tgtgggagaa gttcaagatg taataataca
     6601 agatggagat gactatgctc ttgatataac actaaatacg aatggtccag ataaagtggg
     6661 agcacagata atatctcctt caggtgaagt tagtcatgat ataaggtatt ctccagactt
     6721 ttatatatat agaggaaaat ttaacttaga aaatactact tatgcaatga gatttattta
     6781 tccatatatt acctctggaa aagaaaattt ggagataaga ttaagagata taaaacctgg
     6841 agtatggatt ttaagattga cttcagaact tataataagt ggagaatatg acatatactt
     6901 accaaataaa aatttgatag ctccagacac aaggttttta gaccctgatt cagtagctac
     6961 tataactatg tatgctgcta gtgatgatgt aattacagtt ggtacattta ataataagac
     7021 tgatagtatg tggattggtt cttcgaaagg accaattaga ggaagaggaa ttaagccaga
     7081 tatagtagct tcaggtgtag atataatatc cacatataaa aatggaacat ataatacagg
     7141 aacaggaaca ggagtgagca gttctatagt cacaggtgtt ttagccttat tgatggaata
     7201 cttagaaaaa caggataatg taccgagatt atcattgttt acacaagttt taaaaacata
     7261 tttaatattg ggtgctacaa aacttgagat atatacatat ccaaatgtat cgcagggata
     7321 tgggatttta aatttaaaaa atacgattca acagatagca aatactctat agataagaac
     7381 ctatgtaaaa ttataattga ttagtaattt aattgtatca aatactttag atagagtaga
     7441 aaaatggcat aaaaaataaa tatgaaaatt aaaaaaacag ttttatattt tgaatacaca
     7501 aagtaaatat tttgtatata aataggtata aattaagtat tgaaaagata tgatgttaat
     7561 ttaaaaatca ttataattta gacttatgaa ttttatttgt aaaattgcta aaactattac
     7621 aaaataaata atagaggtga tagttttgga aagtaaaaag gcaagagcat taaaaggtaa
     7681 agataataaa agacttaaaa gttcactttt agttggaaat gagtcgacag cagcatgggc
     7741 tgatgttgaa aaattaaaac ctcatagtaa agtttcaata ccttcaatta agggtgtcga
     7801 agaagcaaaa gactgggttg acaatggaag taaattataa aattttggaa atttaagtaa
     7861 taaagaagta atgaagataa gtatttatta tcattatgca aggtagaatt attatatttt
     7921 aaataacaat cagtatcaat tatataaatt tattgactaa aaatttataa attggtataa
     7981 ttttgttaat tagtagaaat aataaaagat aaatactgtg aagagaagag tagatataaa
     8041 atgtagttct agcgagttga ggatggtgaa agctcaatac gaggtttata ttgaagaaca
     8101 tcttggagtt tctaatcgaa agcttattta gtaagtagac ttagacggaa ggcaccgtta
     8161 taggctttaa gcattgctta actaagaggt cattatgaca actagggtgg taccgcgaga
     8221 gtaatagtct ttcgtccctt tatataggga tgaagggctt tttttattga aattatattt
     8281 aaaagaaatt aataacaatt atactaggag gatttaaaat gcaaaaggaa tttataacag
     8341 taaaagaatt gtacagagaa aaagaacagt acatagggaa gactgtaaaa gtagctggat
     8401 ggataagaac atctagagta tctaaaaatt ttggatttat agagctaaat gatggaagct
     8461 tctttaaaaa tatgcagata gtatttgatg agaaagtaga aaattttaaa gaggtaggaa
     8521 aattagcaat aagctcatct atacttgtag agggagagtt agtatctaca gaaggggcta
     8581 aacaaccagt cgaaatacat gcaaaaagca tagttgtaga aggggaatca gatagttcgt
     8641 atccactaca aaagaagaga catacgcttg aatatttaag aacgatagca catttaagac
     8701 caagaagtaa tactttttca gctgtattta gagtaagatc aatagctgcc tatgcaatac
     8761 acaaattctt ccaagaaaga aactttgtat atgcacattc tccaatcata acgggtagtg
     8821 actgtgaagg tgcaggagaa atgtttagaa taacaactat ggatttaaat gatattccaa
     8881 aaactgaaga tggtaaaata gactatactc aagatttctt tggaaaagag gctaatttaa
     8941 cagttagtgg tcaactaaat gccgagataa tggcactttc ttttagaaac gtttatactt
     9001 ttggacctac atttagagct gaaaactctt atacaggaag acatgcttca gaattttgga
     9061 tgatagagcc agaaatagtt tttgcagacc ttgaagataa catggaactt gcagaagata
     9121 tgataaaata tgttataagc tatgtattag aaaatgctcc tgaagaaatg gaatttttta
     9181 atagttttat agataaagga ttgttagaaa gattaaataa gatagtaaac tctgagttta
     9241 ttagaataac gtatactaaa gcagtggaat tattaattga atctggtcat gaatttgagt
     9301 atcctgttga gtggggatgt gaccttcaaa ctgagcatga aagatatata acggagcaaa
     9361 tatataattg tccagtgttt gttacagatt atccaaaaga tataaaagct ttctatatga
     9421 gaatgaatga agacggtaaa actgttagag caatggattt attagttcct ggagttggag
     9481 aaatcgtagg aggttctcaa agagaagaaa gagaagatgt attgttagat agaattaatg
     9541 aaatgggatt aagagaagaa gattattggt ggtatttaga acttagaaag tttggtactg
     9601 ctactcactc tggatttggt cttggatttg aaagaataat tatgtatatg acaggtatgt
     9661 ctaacataag agacgttata cctttcccaa gaactcctaa aaatgctgaa ttttaataat
     9721 tatatataat aaaacttata taactttaag tataaacact aaaatgactt gcatatttat
     9781 ctattttaga gatatgcaag ttatttttat tgtactataa atatataatt tgattacttt
     9841 tattttgcga tataatactt ataggtttat ataatagtat gtaacttttt aataaaatgc
     9901 aacacaatta cgtccctgtt cttttgcagt atatagagcc ttatcacaat tacttataaa
     9961 ctcatttaat gttattgcct tttcaatttt ctttgtataa actccaatac taacagttac
    10021 acattttaaa ggaacatcat cacgctcaaa attgcaggac tctataattt ttcgtaaaca
    10081 ttctgattta agtttagcat ctgtctcatc acagttaaaa atacatataa aaaattcctc
    10141 accaccatat cgtatagcat gttcattttc agaacttgta aaatctaaaa ttactttggc
    10201 aatattttgt agacaatagt ctcccttttg atgtccataa ttatcattaa attgtttgaa
    10261 ataatctata tctatcatca ttccagttat aggttcttga tttgcatggc tgattaattt
    10321 tttttgtaga atatcttcaa ggtatctacg gttgttcatt ttagtaaggt cgtctgtcat
    10381 aactttgtcg ttaagtaaat tatttatatg agatatttct tcatattgtt gactaattaa
    10441 aagtttatca tagtaagtaa atacacgatt tctatatagc attgtagaaa caaaaatggc
    10501 aagggatgtt ataaaaaatg tgttgacaat attactaaac tcattgcctg gtatagtttg
    10561 aatcccaggt aagaataaat taagaaacaa aaagcatcct ccaaaaacta ttactgattc
    10621 tccaaatttt aatactgaga aagctgcagc tgctaacata atataactaa atacacttag
    10681 gtcatttcca cctaactggt caagtagagt aattacacaa ccccataggc agaaaaaagt
    10741 cacataaatt atccataaat ttatataaaa cgtacaacaa tccttttttt tattccaaag
    10801 ataagaaaat acaaacataa agacagaaga tacacaaaat agtgttacat acatataaaa
    10861 ataccattgg cgtcttggtg tggcaaaagg gcctccttct ctagctgaga ttgatatcat
    10921 cataattatt tgagatatta ctattattat gcaaatgatt ttacccgtat gataaagata
    10981 attgcagagt tctttttcaa cattttcttt gtgttttttg tctagaggaa atccaaaaaa
    11041 tttttttatt ttttctaagt tcatataagc ctccattaaa aataaagcat aaaaataagt
    11101 attcctttct atcattagat atttggaata cttcgtttat gatttaatta tatcaaaata
    11161 tattgtgtgt aacaatctaa aattgtgata gataaaattt attagctaat gttgagtaac
    11221 tttattaatt aatactttac tataattaag atttacagat agtttgctgc tgaaaataaa
    11281 gaatagaata aatttaaatt aagcataata aaatataaat aataaagttc gcattaacaa
    11341 actatttaaa tatcaagacc tgttaaaaaa caacagcaat aaacaaataa aatagataaa
    11401 tatatccaat taaggtataa ttaagtttta tatgatatag ttatatttga taatttacaa
    11461 tagtaaaact tggagggaaa aaatgggtga aaagaaaata aataatatga attattcaca
    11521 taataattat tccaaaaaga caggtgaacc aactagaaaa ataaaaaata gccatatcac
    11581 tcttaaaagt aaagaagaaa aaatttgttc tagttgcaat aaagaaaata atactaagga
    11641 taattactgt aaattttgtg gaaatgaact ttatgaaata gcatcattaa gaccacttga
    11701 aacaaaacta gacttgaaat ctaaaataaa agagctttca tatcatgcaa ataaaagagg
    11761 tgtattttta acaacattta caaccatatt tatattgttt attattgcat tgatatttaa
    11821 agctattata actattcaat ttaatgatat tagttattta ataaatccag cacatataat
    11881 cctagctctc aacttgggtc aaattagtgt atctatgtct accatgatgg gttctgggtt
    11941 tataaatgcc aatataggtt tgttgatatt acttataatc cctattttgg tattattaat
    12001 atcaaaccta atttttatga gaaaaagatg tagagattca aaaactgtat tagcaaattc
    12061 tctaggagtt ggaatttttt atggattagt tttagctatt ttatctattt ttactaatgt
    12121 aaaaactagt tcacatagta tgttagaata tggatatgca ttagaatata gttatgaatt
    12181 ttttagtgtt cttttaaatg gatttgtatt agggtttata tgtacataca taactactta
    12241 taaaaaaagt tatgaaaagg aaaatatgta tttatctctt ttttcaaatt ctataagaac
    12301 attcatatta ggttatgttt tagtattagt aatactattg gtactaacta tatctgatag
    12361 tagttactta aatgaactag atatgagtag ttattcaaat ggattaaatt tatttactat
    12421 actcccacaa atagctagtt atatgtgggc ttttgcaaat ggaatttcag taaccataat
    12481 aaactcaaca gtatcaatgt ttactttaag ttcttcatct ttatttggag atactaaatt
    12541 aatgttttat gcaatgggag cattgtctat gttaatatta ttattaaatg gatacaagct
    12601 aagatttaag tataatacag atagtataag acctataata gtatttagta tatattatgc
    12661 atttttgatg ggaatattgg ctttatttag tacatttata ctagatagta atattaattt
    12721 ctttaataca actaattatg gaacaacttt aataatgcaa tttaaagtct tacaagctat
    12781 tgtaatttca tttgtatata gttttgtgat atctttaata ggatataagc taaattcagc
    12841 tgattaaata tgattggagg gaatttctgt ggaaggaaat actaataata aagtagatga
    12901 taaattttct aaggttaaga aaaagtttgg tagtggaaaa tttaaagttg aattatataa
    12961 agaaaaatca aaattaaata gagagattga tgatattcaa gaaaagaaag caaagatatt
    13021 cttggaaatg ggaatactga catatcaaaa aattagagaa gattctatta atgataatag
    13081 ttttgataaa ttctgtgatg agttactaga acttgataag ttaatttatg aaaaaaatat
    13141 ggaaattaat gaaatggaaa tggcagaaag taatgtaact tgtgagtgtg gttatgttgg
    13201 aaatgtaaat gataaatatt gtgctgaatg tggtaaaaaa tttgaattgg aaaatgaatg
    13261 tgatgatttt ataatttgtg gttattgtga aagtgagata gatacagagg ctgaattttg
    13321 tccatgctgt ggaagaaaaa ttataatgga tttagaataa tattgggaaa cctatgtata
    13381 gtatacatgg gtttttttat tgaaattatt taaatggact tataacagta gttatataaa
    13441 atgaaaataa acaccaaaaa aatgaaataa aatttctttt aaatgtaaaa aacaagctaa
    13501 tatataaaat aaatcagtaa aaatatagat gcgagaaaaa aatatgaaaa aatattgcaa
    13561 agaaaaagtt ttcatgttat tattaataca taaatcaaga aaataaattt cagaaacgag
    13621 gtaatttaaa aaatgctaga taaggtaaag ggaagattaa tagtatcatg ccaagcttta
    13681 gaaaatgaac ctcttcatag tccttttata atggggagaa tggctaaggc tgctatggaa
    13741 ggtggagctg ttggaattag agctcaagga gttgaagata ttattgaaat aaaaaaagtt
    13801 actggacttc ctgttatagg tattataaag agaaactatg aagattcaga tatatatata
    13861 acgccaacta aaaaagaagt tgatgaactt ttaacaacag ggtgtgaaat gatagcatta
    13921 gatgctacca atagagttag accaaataat gaagacttaa aagaacttat aaagtatata
    13981 aaagaaaacg gtgttctagt aatggcagac atttcaaatt atgatgaggc tatcaaagca
    14041 caagagtacg gtgtagattg cgtttcaact acactatctg gatatactcc atatactaaa
    14101 acattagaag gtccagattt tgtattaatg gaaagattag ttaaagattt agaaatacct
    14161 gtaatagctg aaggaaaggt aaatactcct caagatttaa aaaaggtctt tgagttgggt
    14221 gttcattcat cagtagtagg ttcagcaata acaagaccac aattaataac agaaaaattt
    14281 gttaaagcaa ttgaaattaa ttaaaaatta atttataaat taaaaaatta ttatatttaa
    14341 ctatacttga aaattaaaat tggaggtaaa gatatgagaa caacagatat gaagggaatt
    14401 tattcagcat tattagtttc atttgataag gaagggaata taaatgaaaa agggttaaga
    14461 caaataatta gacacaatat agatgtttgt aaagtagatg gtctttatgt aggaggaagt
    14521 acaggggaaa acttcatgct ttcaactgat gaaaagaaaa gaatatttga aatagctaaa
    14581 gatgaagtga aagaagaaat aaaattaata gctcaagttg gttcagttaa tttaaaagaa
    14641 gctgtagaac ttgctaaatt tacaactgat ttaggatatg atgcaataag tgctgttaca
    14701 cctttttact ataaatttga ttttgaagaa ataaaacact attataatac aataataaat
    14761 tctgtagata atagattaat aatatactct ataccatttt taactggtgt tgatatgagt
    14821 ttagaccagt ttggagaatt atttgaaaat gaaaaaataa taggtgttaa gtttacagca
    14881 gcagatttct acttattaga gagaatgaga aaaacattcc caaataaatt aatatttgca
    14941 ggatttgatg aaatgatgtt accagctaca gttttaggtg tagatggggc aattggttct
    15001 acattcaatg taaacggtgt cagagctaga caaatattcg aattaactaa gaatgaaaaa
    15061 atatcagaag cacttgaagt acaacatgtg actaatgatt taataacaga tatattagga
    15121 aatggcttat atcaaacaat taaattacta cttgaagaac aaggtgttga ggctggatac
    15181 tgtagacaac ctatgaaaga agcaactgat gaaatgaaat caagagcaaa agaaatatac
    15241 agaaagtatt tttaataaaa tacttttagt atgggaggat tagtcaaatg gtaggattta
    15301 cttggataga ttttgcaata ctagtggttt acttattggc agttttattt gcaggattgt
    15361 tattttcaaa aaaggaaatg aagggaaaag agttcttcaa aggtgatgga actattccgt
    15421 ggtgggttac atcagtatca atatttgcca cattattaag tccaatatca tttttatcat
    15481 tagcaggaaa ttcttatggt ggtacttgga ttttgtggtt tgcacaatta ggtatgttta
    15541 tagcaatacc tttgacaata aaatttttct tacctctgta tagtaggtta gaaatagata
    15601 cagcatatga atacttagaa atgagatacg aaagtaaagg tcttagagta cttggagctt
    15661 tgatgtttat aatatatcaa ataggacgta tgtctatcat aatgtatctt ccatcagtgg
    15721 ttctagctgg tcttacagga atacctgtaa atgtattgat agtagttatg ggtgtaatag
    15781 caataattta ttcatataca ggtggattaa aggctgtctt gtggacagat tttatacaag
    15841 gtatggtatt aatagtaggt gttacaggga cattgttcta tttaatagca agtataaatg
    15901 gtggttttgg aacagtaatg gatactctta caactggaca caagttctta gcaagtaatg
    15961 aagttatgtt tgataaaaat atactatcta caagtgcatt tataatattt attggagctg
    16021 gtcttaatac tttttcatca tatgtatcga gtcaagatat agttcaaaga tttactacaa
    16081 caactgatat aaagcaactt aataaaatga catatggaaa tggtgtttta tcaatgggac
    16141 ttgcaacagt attttatcta attggaactt gtttatttat atactatact caaaacccag
    16201 atttagctca aacagttcaa caagaccaag tatttgcatc atatatagct tatgaattac
    16261 cagtgggtat aacaggaata ctacttgcag cgatatatgc agcttctcaa tcaactttat
    16321 cgacagggct taattcagtt gctacaagtt ggactttaga tatacaaact atcataacaa
    16381 aagatataag tatggaaaag caaactaaga tagcacaata tatatcatta ggtgtaggta
    16441 tactttctat agctgttgca atagtattag caaatggaga aataaagtca gcatatgaat
    16501 ggtttaatag ttttatgggg ctagtactag gtgttttagc aggaatattt gtacttggtg
    16561 cattttgtaa aaaagcgact aaaatgggag catatgttgg attcatagta tcagcaattt
    16621 tagttgttta tttaaaatac cgtatgccag aagtaacttc ttgggcatat tctctaataa
    16681 caatcacgac ttctgtagtg gtaggtacaa tagttagtgc aatagaagct aaagttaaag
    16741 caaaagtatc tttaccaaaa gctgagacta ctgtttatta tgaaaaataa tatttaaatg
    16801 ataaattgtc ttatagagtg attagataaa taatttagtt actctataag attgtataat
    16861 atactttgta tataaaagta taaaaataga ctttataatt atatagggag atagtgctta
    16921 tgatatttgg aaatataaat catagtaaga catattcaac attgcatgaa gatttactta
    16981 gatgttttga atatgctaaa gataattcat taatagatta tgaaaaaggt acttatacaa
    17041 tagatggtga tgatattttt gtgaatattg tagagtataa aacttgtgaa aaagaagata
    17101 gattctggga agctcataag aagtatatag atgttcattt gatgcttgat ggatgtgaac
    17161 gaatagatat aaattttata gaaaatttag aacaaaaaat atatgaagaa aagggcgatt
    17221 tcttgcctct tgatggtaaa aataatggat acatggaact tagaaaaggt gattttttag
    17281 tttgttatcc agaagatgct catatgacag gaataaaagt tttagaaaaa gaaaatatca
    17341 aaaaagctat ttttaaggtt ttggttagat aatgataatt tatataacca ctagggctga
    17401 aaatagtgat ttaactttca gcgattagtg agacttcgta aattttagtt agattactat
    17461 tttcagcctt agttttttat gagaaaattg aaaataatta aaagcttaaa attttgtaaa
    17521 ggagttaact tatggaaaat atagatgtat tcttattaat aggacaaagc aatgctagag
    17581 gattgggaaa tccaaaagag agcatcattc caaatgaaaa ttgttttgaa tatttgagta
    17641 ctgatgaaat tataaatatg agatgtgagc tagagacttc agaaggtgat ggtactatag
    17701 cacctgcatt ttcaaatgaa tggaataagc ttactggaaa taaagtttgt tttattcaca
    17761 atgcaaaaga tggttcaaga ataaaaaact ggaatcatga taataactgg tttctaaatg
    17821 acactataga aaaatttaat acaggctgta ctaccttaag taaacattat aatatagaaa
    17881 ataaatacgt tatttggatt caaggtgaaa gtgatgcaaa atatggtagt gatgcattgt
    17941 actataaaga aagtctaaaa aaaattgcgt ataggcttaa agaagaatgt atgattgata
    18001 aaatgtttgt aagtttaact ggttattggc ttggagaaga tgaatatttt attagaacaa
    18061 gacgaattgc agcagctcaa gaatctgctt gtaatgaatg tgatatactg tgtgtaggaa
    18121 gtaaaattgc tatgcaattt catgacagag gattaactat tgatgatgtt cattacactc
    18181 aagaaggtct taatatgtta ggagaggact tatgtaaaaa tatttataag tatcatataa
    18241 ccaaagaaaa aagtgtatta agtgatacta tagacttatc agaagcaagg aaatatatct
    18301 gtgaattgga aaagataagt aaaagatttg tgtaatataa aattttaaat agagttgtta
    18361 atttataaaa ataatttgta tggagatatg ttatgaaaaa ttacgtttgt atagatgttg
    18421 gaggtacttc aataaaatat ggttttatta gagaagatgg atttataatt gataaatcaa
    18481 gtcttgatac tgaagcaaag gaaaaaggtg gagaaggaat attagccaaa ataaaagata
    18541 tagtaaaaaa atatatagag gaaaatgaaa taagtggtat atgtatatca actgcaggta
    18601 tggttgaccc agttgaaggt aaaatactat ttgcattaga agaattaatt ccaaattata
    18661 agggtatgca attaaaaaaa gaagtagaaa aagagtttaa tataaaatgt gaagttgaaa
    18721 atgatgttaa ttgtgctgga cttggtgaag tgtggcttgg cgcaggtaga ggtgcaacat
    18781 cttctatatg tttaacaata ggtactggaa ttggtggatg tattataata aacaataaac
    18841 tgataaatgg gtttagtaat agcgctggtg aagtaggata tatgaatata aatggaagtt
    18901 cttttcaaga attggcatct actagcagtc taattaaaaa agtagcaaaa ataaaaaatt
    18961 tgaatgaaaa ggacttaaat ggaaaaataa tttttgattt agcaaagaat aatgatgaag
    19021 attgtttaaa agaactcgat aatatgataa aatcattagc agttggaatc gcaaatatat
    19081 gttatgtaat aaatccagaa gtggtaattt taggtggtgg gattatggca caagaaaagt
    19141 tcctaaaacc aaaaatagac aaagcattaa aggaggttct tatagagaga gtttacaaaa
    19201 acactaatat agaatttgca aagagacaaa atgatgcagg aatgcttgga gcattatata
    19261 attttttaaa caaaatataa agaatagaag ggtttttaat gagtatttta gaacaattgg
    19321 aatcaccaac ttttaaagtc acaaaatcag ataaattatt aatagcttat ataaaagaaa
    19381 atatagatga tgtattttat aaaccaatat cacaaatagc taaagagagc aatattggtg
    19441 aagcaactat aactaggttt gtaaaaaaaa tgaattttaa tggattacag gattttaaag
    19501 ttactttagc acaagaaata tcaactatca ataaaaaaaa tattataaat aaaaatatac
    19561 aaaatgatga gccagctttg gatacagcaa aaaaactttt aagttcaaat gtaaccactt
    19621 tagagaacac agtagagata atcaatagta aggatgtaca tgactgtgca aggcttataa
    19681 taaatgcaaa gaaagtttac ttcataggca ttggatattc tggtataata gcacaggatt
    19741 caaactataa atttatgaga ataggcctta attgtgtaag ttttgatagc agtcatacga
    19801 tgataatgat gtcttccata atggaagaag gagatttaat aattgcaatt tcacattctg
    19861 gtgaaacaga agagattata aaaactgtaa agcttgcaag agccaataat gctaaaatta
    19921 tatcaattac tgaaaataaa aattctgaat taaaggatat ttcagatgta cacttatctt
    19981 atgtatcagg agaaacagta ctggaaactg gttcaatatc ttctaaatta gcacaatttt
    20041 tcattattga tttagtatat acacaggtag taaaagaact ttctaatgaa gctattgaaa
    20101 ggaaaattaa aactacaaat gctataaaat tgtttaaaaa tgaataaaat aagaaatttg
    20161 taatgtttta tagagctctc ttaaaaattt aggaatggag agatattaca tgtctaaatt
    20221 aaaagattat aatattgata aagtaataat ttttaataat ttaagtacta aaacgaagaa
    20281 tcaacttaaa gaaaaagcta aactaaaaag attacaaaaa aaagaaattt tattttatga
    20341 aaaagatagc ttagacagtg tttatatact tttagaagga aaggtatcta tttttaagat
    20401 aagtgaaaat ggagagagaa aagtaatttt catattaaat agtggggaag tcataaatga
    20461 tattacattt gactcttcta aaaactccac tgttggctgt gaagcatttg aaaattcaat
    20521 tgtagcttat tatagtattg aagaattttt agaaattatg caaaatgatt ttcaacttac
    20581 aaaggatatt atttcttata tggaaagaag aataagacgt ttatatagac agttgaaaaa
    20641 ttctatatcc ataaaagtag ataaaaaact tgcagcaaaa ttatataggt taagtagaga
    20701 atttggagtt tgctgtggag aatggacttt actaaatgta aatattacag ttacatattt
    20761 agctgatatg cttggctgta aaagggagac tgtttccaga atgataaagg tattgcaaaa
    20821 agaagaactt attaagattg ataataaagg tttttatgtt aaagaaactg aattatcaag
    20881 gtatttcaaa aataattaat tatgattaag taaaagtatt attagaattt taattaaata
    20941 aaaatattat taagagaatc tatttataga ttctttttta ttgtctaatt tattaatttt
    21001 tattttaccc tattgaattg tataaaaaag caaataagat tctttattat tcaaaaaatt
    21061 gagtagataa tagttttatt gtatttaatg attgtatcta agtgattaga tttgaaatcg
    21121 aataatatag ataataaaaa aatattaaca gagattagta aactctatta atattttttt
    21181 attatttttg aaactgtgat aattatcaca gaagcataga aaataaagtg ttaagattta
    21241 aacaagatag caagtaagta aaactaaaat ataagaaagg tgataaaaat gaaactaaaa
    21301 ttagattcat ctaagttcaa tgaaggtctg aattatctaa aaaaagacta caagatattt
    21361 gcaccagttt taatcccatt taaaggtact ttttcagata ctgatgttat aagatacaag
    21421 gaggtaaacg cttttgaaga aatggaattt gctaagaaag caaacttttc accaaaagaa
    21481 gttgtacttc ccataaatca agtattgttt tattttactg aaaaagagtt taaggaaagc
    21541 gatttagaca acaagaaaat tttaattttc ttaagagctt gtgacataaa tggtataaaa
    21601 agacttgatg aaatatatct aaataatggt gaagaaaaag attattttta taaaaatatc
    21661 agagataaag taaagtttgc acttgtaggg tgtaaggaaa gttttagaaa ctgtttttgt
    21721 gtgagcatgg attctaacaa aactgataat tattcaattg gattaaatat agaaggagat
    21781 acactgtact tagatataaa ggatagtgaa tttgaagtat ttaatggaga agcaactgaa
    21841 tttaatgttg attatgtaac tgataattta atatctgtag atgtgccaga gaatattgat
    21901 tcaaatgaaa ttataggaaa ttcaatatgg gatgaatatg atacaagatg tataggatgt
    21961 ggtagatgta attttgtatg tccaacatgt tcatgtttta caatgcagga tattttctat
    22021 aaggaaaacg aaaatgtagg tgagagaaga agggtttggg cttcttgtca agtagatgga
    22081 tatacagata tagcaggtgg aaattctttt agaaaaaaac aaggtgaaag aatgagattt
    22141 aaaactatgc ataaaataca tgattttaaa aaaagattcg gatatcatat gtgtgttggt
    22201 tgtggaagat gtgatgatgc ctgtccgcaa tacatatcat tttcaaagtg tatagaaaaa
    22261 ataaatgatt tagtaattag taaggaggaa gtataaatga acccatatat accagtaagt
    22321 gcaaaaatac tagatatagt taaacatact gataaagaat ggacttttag agtaaactgc
    22381 aatacaaaag gtgtattgcc tggaaagttt tatgagatat ctatacctaa atacggtgaa
    22441 agtccaatat cagtatcagg atatggagag gattatattg actttacaat aagaaatgta
    22501 ggaaaagtaa ctagcgagtt gtttaattat aaagaaggag attctttttt tataagaggt
    22561 ccttatggaa atggatttga tgtatccctt tatgaaggaa gagaaattgt agtagtggca
    22621 ggaggaagtg cattagcccc tgtaagagga atagttgaat atttttataa taataaagaa
    22681 aaatgcgaaa agtttaaatt aatagtagga tttaaatcac caaaagatat tttatttgca
    22741 gatgatttaa agagatggag taaaaaactt gatattttag ttactgtaga tggagcagag
    22801 gaaggatata gtggtaatgt aggattagta acaaaataca taccagaatt ggatatgaaa
    22861 gatataaaca atacttctat agttgtagtt ggacctccaa tgatgatgaa atttacagta
    22921 gaagaatttt taaaaagaga tttagatgaa aagaacattt gggtttctta tgaaagaaaa
    22981 atgtgttgtg gaataggtaa atgtggacat tgtaaaatgg atgatactta catatgttta
    23041 gatggaccag tatttgatta ttcatatgct aaaaatctta ttgattaggg ggcgaagttt
    23101 gtgataagag atttaaatac caaaaaagta atgaaaaatg cttatagaat tacaaaaaca
    23161 aaatatgaga cttctttaag agttagagta cctggtggtc ttattgaccc tgagagttta
    23221 gctgtagttt ctaaaattgc aagtgagtac ggaaatggac aggtgcacat aactacaaga
    23281 caggggtttg aaatattagg aataaatatg gaagatatgg aagaaataaa taaaattata
    23341 caacctgtta ttgaaaaaat gaatataaat caaagtgaga aaaacgcagg ttatccagca
    23401 gcaggtacaa gaaatatagc agcttgtata ggaaataaag tctgtccaaa ggctcaatat
    23461 aatacaactg aatttgctaa aagaatagaa aaagctatat ttccaaatga tttacatttt
    23521 aaagtggctt taactggttg tccaaatgat tgtataaaag ctagaatgaa tgactttgga
    23581 attattggta tggctttacc aatatatgaa aaagatagat gtgtaaattg tggagcatgt
    23641 gtaaaaaaat gttctaaaat atctgttgga gcattaaaaa cagaaaataa taaggtggta
    23701 agagataaag ataagtgtat aggatgtgga gagtgtgtac taaattgccc aacaaatgca
    23761 tggactagag atgagaaaaa atactataga ttagctataa tgggtagaac aggaaagaaa
    23821 aaccctagac tagcagaaga ttttctttta tgggtagatg aggacagcat aataaagata
    23881 atacttaata cttatagata tgtagaaaag tatatagata aagatgcacc aggaggaaaa
    23941 gaacatatag gatatataat tgatagaaca ggatttatgg aatttaaaaa atgggcactt
    24001 gaaggtgtag agcttccaga aataactaaa atgtacgaaa acatatactg gagtggaatt
    24061 aaatatctat aaattgagta aaacatatat ttgaataaat taaaatttaa tagaaggaag
    24121 agggaattat gcataaagaa actttggata aattaactaa tgcagctata aataagataa
    24181 atttattaaa cacaagtaaa gtaaaatatt tggtatcttc tgcgtttgca ggactttatg
    24241 taggtatagg tatacttttg atatttacta taggaggact tttgactgat gcaggttcac
    24301 ctatgactaa gatagtaatg gggttatcat ttgcaatagc actaagtttg gttataatga
    24361 cgggaacaga gttatttact ggaaacaata tggttatgtc tgctggtatg ttaaataaag
    24421 gtgtaagtat aaaagatact tctaaaatat gggcatacag ttgggtaggt aatttaatcg
    24481 gagctttggt tttaggtctt atatttgtag gaactggtct agtagacaaa ggacctgtag
    24541 ctgaattttt tgcaaataca gcagctagta aagcatccat gccatttaca gctcttttct
    24601 ttagagggat tttatgtaat attctagtat gtgtatcagt gttgtgttcg tttagaacta
    24661 atagtgatac tgcaaaaata attatgatat tcttatgttt atttgctttt ataacatcag
    24721 gttttgagca tagtgtagca aatatgacaa tttatagtgt ttcattattt tcaccaacaa
    24781 taagtacagt tactattgga ggagctattt ataatttagt agctgtaaca cttggaaata
    24841 ttgttggagg agctttattt atgggtcttg gaacttatat attaggtaaa gaaaagctta
    24901 attaaattta ttgtataaat tataactctc ttgataaata catttttagt attattgaga
    24961 gagttatttt tatatttttg aaaaaatatt tgaaacaaaa aaaatatggg agcatacgaa
    25021 aatatatcgg ttatatataa aaaaaatacg tttatatatg aattatatag ttctaaatat
    25081 aaaaaaagtt aaagtcctac cgtaaaaaag cgcattttga ataagataac aaatatgata
    25141 aaattggtct tgttgaaatt tttagggggg atatgatgac aaagaaacta gtaatatcaa
    25201 aaacaaagtt gtttattttt ataatagcat ttatttctat atttatatat ttatttggaa
    25261 gtaaaaatac acttataggt gtaggtatag taacagctat gctaacactc ttggaaagag
    25321 atttaactat ttctccaatt aaaaatttac tgaagtattt agcaataaat ataatcttag
    25381 gaatactatc attttttgca gtacaaaata tgtatttagg agttttatta aattttatag
    25441 cattatttat aatagggtat gtatttagtt atgacttaaa gagagcagta tatgtacctt
    25501 ttggtctaat gtatatattt atggtaagta tacctgtagg aaaaagtgaa tttcctatga
    25561 gattgtcggc tttagctgtt ggagcagtta taataatgat tgctcaattt gttatgaata
    25621 gaaataggat gaaaaatgtc ggagataaag aactgatatc tatatgtgat gaattattag
    25681 aaaaaattag tcttttaaaa aatactatta atgatgatag ttctataatt aaatctagta
    25741 tgagaaaaat agatagctgt aattatagaa taaattctat atctaaaaat ttgaaaatgg
    25801 ttatttttga taatagaaaa gatgactttt atatcagtat tagaggtata gacataatga
    25861 atattttatt ttcattagaa agaataagtt taatcatgga aagatacaaa aaggatagta
    25921 aagaatttga agatgaagat ataaaaaata ttttagaaga aagtagcata aatagtaaat
    25981 cagatgttct agttgtagca acgaaagaaa taaactatat taagatgtgt ttagaaaata
    26041 aagataccat aactgataaa gagatattag gatttagaga ttatgttatt gctcaggata
    26101 ctaaaaatat aaatttaaaa gaaatttata gtgttttaga aaatttatat gagtttttag
    26161 tagattataa aaaagtaaaa tcaagagacg aaaagaaagc tgaaagaaaa tcaaagatac
    26221 ctcatgaatt taaacgacta tcaatatata agaaaaactt taatttaaat tctataagat
    26281 tttcttatgc agtaaagatt gctttagcta cagctgtagc gggttttatt atggattatt
    26341 tccatttaag agatggaaga tggataatgt taactgtctt ttcattaaca caaccttacg
    26401 cagaaaattg tatacaaagg tctagaaaaa gaatagaagg tacatttata ggagctgtaa
    26461 tatttattgt attattttca ataataaaag atagtacatt aaggtcgtta atagttcttt
    26521 tagcagggta tataaactct tatgtagttg attatagaaa attaatggta tgtgtaactg
    26581 tttcagctct tggttcagca gtagttatgg gagacccaaa tgttttaacc ataagcagga
    26641 tttcatatgt agcattagga gcaattattg cattaatagt aaataagttt atattaccat
    26701 atgatgctaa aacaggctat caacatgtta tagaaatgta taaaggaata gttaaaaata
    26761 taattgatga agtcaataag tctatagaaa atgtagctga tgtttactat ataaaaaatt
    26821 tattattgat accatcactt attgaagata gacttatgtt gataaatgct atatataaag
    26881 ataaacatca agaggatttt ttagaaaatc agaaattact aataagtaat atgtataatc
    26941 tatatataaa tgttaataaa aataaaataa aagatgaaga tgttgaaaaa atattgagag
    27001 atactaatta tatttcaaat tacaatgtag ataagtatga tgaaggaaga agtgtaattt
    27061 tagagagtat tgtaaatact aaaagtctag gtgacaagat aatatgtcta aacttactgc
    27121 aaactctaaa tggtgtcaaa gaaatgtata gaataagtaa tataactaaa gtttcaataa
    27181 aagaagcagc ttagatatta aattatagaa tagccatata tttaaaataa agtatatggc
    27241 tatttgtttt ataaaatact aaaagaaaat aatatataaa aaacaaaaaa catatattta
    27301 tgaattttat atgaaaatag ttaaaatatt gatttttttc attggttgaa aaaacaattt
    27361 acttaggata aactataata gtattcaaat attatggggg ttagatttat gagtaaagat
    27421 gtaaaggtaa agcgtaataa gaaatatgat acatttagta taactatgga acttgagaga
    27481 cctttacttt atgatgaggt tgagaacaaa gatgataaaa ataataatag aaaatttaac
    27541 ataaagaata agatatttaa gggaataggt atactatttg tattgatttt gcttggcttt
    27601 ttcatatgga taaataaaac atatgaacct caaaagctgg caaaagaagc tctagtcagc
    27661 aatagtaaag ttgaagtaac tgtaaatgaa aacatttcat ttacaccaaa aggaagaaaa
    27721 gtttctaaag gtttaatttt gtatccagga gctaaagtag aaatagaatc ttatgctcca
    27781 cttgcaagaa aaatagcaga aagtggatat gaggttgtaa tcgtaaagat gccacttaat
    27841 ctagctatac ttggaactaa taaggcacag aaagttatgg attcttacaa caacatagaa
    27901 cattgggtaa taggaggtca ttcattagga ggagttgcag catcaaattt tgcacgtgat
    27961 aataaattaa ttgaaggcgt tgtattttta gcttcttatc caatgggtga tgagttgaaa
    28021 gaattaggaa aaaaagttat atctatatgg gggagcaaag atggagtagt caattttaaa
    28081 agtcttgtag aatcaaaaca aaaacttcct gatgatacaa cttatgttga gattgaagga
    28141 ggaaatcatg cacaatttgg agactatgga aaacaaaagg gagataatga tgctattata
    28201 agtcaagaaa aacaacttaa tattactgcc aatagtatca ttaaattttt aaagaatata
    28261 tcttaaacta aaatttaaaa aatataattt tataagttat tatttaaagt aaatattaat
    28321 aatataatag aatgaatatt ttattacaag ggggatttta atatggaata cgatatgcca
    28381 ctttacagac caccaagtga ggcttatagt cttataatac aagtcacact aggatgttct
    28441 cataacaaat gtacgttttg tagtatgtac aaatctaaaa aatttaaaat aaagccacta
    28501 gaagtaataa aaaatgaaat tgatatattt agaagatatt ataagcatgt agaaagaata
    28561 ttcttagcag atggagatgc attgataata ccaatggaga aattaagaga tattatttta
    28621 tatataaaag aagtttttcc agagtgtgaa agaattacta tgtacggctc tcctaaatct
    28681 atagagaaaa aatctgatga tgaacttaaa gaattaagaa aacttggtgt taaaatgatt
    28741 tatctagggc ttgaaagtgg aagcaatgaa gtattagaag atattaagaa aggttttagt
    28801 agtgaacaat taataaaagt tggtagaaaa gttaaaaaaa gtgggattaa attatcagcc
    28861 actgtaatag caggtcttgg aggaactaaa aaaacacatc agcatgcagt tgatacagga
    28921 aaaatgttag gagcaatttc accagattat gtgggtgtac ttagtttaat ggtagaacct
    28981 aatactgaac tttacgattt acttaaggca ggagagttta caatactaga ggataaggct
    29041 gtgttacaag aaattaaaga gatgataaag aatatagatg ctaatgaaaa aattgtattt
    29101 agaagtaatc atgcatcaaa ttatgctaat ttaaaaggtg tattacctga tgataaacaa
    29161 cgtctaattg atgaaattga ttactatcta agtaaccaaa agctaaaaag agaagaatat
    29221 agaagactat agtttttgat atatcaatct atattgatag gtaaatacta agattattta
    29281 gatacaaaaa atcatgctac attaatagtt gcttactact gatgtagcat gattttttta
    29341 ttaaaaaaca aaatggtata ttcatatata atatatcaat aataatgaaa atgtgaacta
    29401 gtttaataga attttaccta ttataataaa aacaggaatt t
//
LOCUS       DAMJWO010000051        29203 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.052, whole genome shotgun sequence.
ACCESSION   DAMJWO010000051 DAMJWO010000000
VERSION     DAMJWO010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29203
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.052"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            726..1193
                     /locus_tag="PC366_002309"
     CDS             726..1193
                     /locus_tag="PC366_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HDF2577818.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALIARILYFSDYFIVILFLIFIINSTKYSPFILENVKRFKVMGCCLLINTIIECVIG
                     YNSNTSLIMIFGDNSGGISPLMVISFIFALMCFVIAETFDKAIKIKEDNDLTI"
     gene            1204..1419
                     /locus_tag="PC366_002310"
     CDS             1204..1419
                     /locus_tag="PC366_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2577819.1"
                     /translation="MAIVVNLDVMMAKRKISLKDLAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDEND"
     gene            complement(2189..2473)
                     /locus_tag="PC366_002311"
     CDS             complement(2189..2473)
                     /locus_tag="PC366_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577820.1"
                     /translation="MLVYNKSFYPNDIFPRLDFSKIKKQLKLIDNDLSDFGRICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYRIVYEIEKLFKSQVGRFSISTYRN"
     repeat_region   2584..3267
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=2710..2737
                     /rpt_unit_seq="tttacattccatatagttaatataaaac"
     gene            complement(4098..4970)
                     /locus_tag="PC366_002312"
     CDS             complement(4098..4970)
                     /locus_tag="PC366_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDF2577821.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
     gene            complement(5364..5942)
                     /locus_tag="PC366_002313"
     CDS             complement(5364..5942)
                     /locus_tag="PC366_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2577822.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            complement(6000..6716)
                     /locus_tag="PC366_002314"
     CDS             complement(6000..6716)
                     /locus_tag="PC366_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDF2577823.1"
                     /translation="MRINKYIASCGIASRRKSEEIILGGRIKVNGSVVKELSFNIDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVRERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKTYVASVKGIISDDEIRQFETGLKIEDYTT
                     APAKIRVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            6907..7992
                     /locus_tag="PC366_002315"
     CDS             6907..7992
                     /locus_tag="PC366_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF2577824.1"
                     /translation="MIIILKENIKYYLIVVFIGILFFKFINTPSNFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEVKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYIDSFIEKNMSNIDFLKTLIPHIQHSLDNLLKEASNFVGKIPKNFLI
                     YTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTARNKADNIIEFFRTTHD
                     IFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPP
                     IAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFG
                     FIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            complement(8147..8806)
                     /locus_tag="PC366_002316"
     CDS             complement(8147..8806)
                     /locus_tag="PC366_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577825.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KYSSKNNDKKSDSNKSDNNNSSSQNQEKPNNSNPTPAPTPQDTTGGSDSGGNSQNSNN
                     Q"
     gene            complement(9023..10315)
                     /gene="lysA"
                     /locus_tag="PC366_002317"
     CDS             complement(9023..10315)
                     /gene="lysA"
                     /locus_tag="PC366_002317"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HDF2577826.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYIEYFKAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSEYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIQLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHEAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEI"
     gene            complement(10333..11526)
                     /locus_tag="PC366_002318"
     CDS             complement(10333..11526)
                     /locus_tag="PC366_002318"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDF2577827.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHVVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     gene            complement(11887..12504)
                     /locus_tag="PC366_002319"
     CDS             complement(11887..12504)
                     /locus_tag="PC366_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577828.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            complement(12674..14374)
                     /locus_tag="PC366_002320"
     CDS             complement(12674..14374)
                     /locus_tag="PC366_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577829.1"
                     /translation="MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVLHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQSFVTDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNDLKDEVLEGTVTRISPDVRGGNTNYYVTLDSNKDIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEKTGTDENTDSKDSENQGNV
                     "
     gene            complement(14771..15334)
                     /locus_tag="PC366_002321"
     CDS             complement(14771..15334)
                     /locus_tag="PC366_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577830.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKLISDYRE
                     DYYYDTMALIYLLMNIQRQSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            complement(15493..16206)
                     /locus_tag="PC366_002322"
     CDS             complement(15493..16206)
                     /locus_tag="PC366_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HDF2577831.1"
                     /translation="MGKVAKILLSLIVIVLVLAGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLVNSQYELELRPTLKDGNLVVSLENVKIGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPITLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKTSVG"
     gene            16498..18162
                     /locus_tag="PC366_002323"
     CDS             16498..18162
                     /locus_tag="PC366_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HDF2577832.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDIPENEGKHFLEQINPNSLEILQGFVEPTQ
                     IKDSKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK"
     gene            complement(18269..19168)
                     /locus_tag="PC366_002324"
     CDS             complement(18269..19168)
                     /locus_tag="PC366_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HDF2577833.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEKNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELDIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVHIECEDSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(19195..19833)
                     /locus_tag="PC366_002325"
     CDS             complement(19195..19833)
                     /locus_tag="PC366_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003356606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HDF2577834.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KVGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKTTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(20170..21168)
                     /locus_tag="PC366_002326"
     CDS             complement(20170..21168)
                     /locus_tag="PC366_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HDF2577835.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KRISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYDYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KAFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADLIRNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(21266..21841)
                     /locus_tag="PC366_002327"
     CDS             complement(21266..21841)
                     /locus_tag="PC366_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577836.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
     gene            22157..22420
                     /locus_tag="PC366_002328"
     CDS             22157..22420
                     /locus_tag="PC366_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577837.1"
                     /translation="MIKNTKQITVEVNEILLQEISKITNDENNILTDLINESIVNYIL
                     ENKKHNIENKDLEEVIKFYKKENTEKPKSAARAIAEAKTHTLY"
     gene            complement(22849..23226)
                     /locus_tag="PC366_002329"
     CDS             complement(22849..23226)
                     /locus_tag="PC366_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2577838.1"
                     /translation="MTITKIPPAELKVMKFIWSSDFTVASKDVIEAMEKLYNWKQTTT
                     LTLLSRLVNKQFLSARKIDRHTHYTVLIGEEEYLHFETKTFLDNMHGSSIESFMKSLF
                     KKGVNEEELNSVEKWVKDIKKDE"
     gene            23567..24679
                     /locus_tag="PC366_002330"
     CDS             23567..24679
                     /locus_tag="PC366_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDF2577839.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRL
                     NEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKY
                     KIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIEAPR
                     YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTI
                     TVNKITSRINGSVILKEPKTESSVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNN
                     LLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
     gene            complement(24887..25363)
                     /locus_tag="PC366_002331"
     CDS             complement(24887..25363)
                     /locus_tag="PC366_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577840.1"
                     /translation="MVKKRLVAVVLSLAMISVGNFSYAHSGGHNSSGGHHNKNKSELT
                     RYYCGGHSAHQPNKGFCPYASTKENSGVTISSVHNEKNHKNYFAEKGYNKGYEDGCKG
                     LYNLSVTEAKSDNLYEKEILKSSYEKGYLIGYNEYKAKKVDDVMKKMLDIPMLASI"
     gene            complement(25562..27187)
                     /locus_tag="PC366_002332"
     CDS             complement(25562..27187)
                     /locus_tag="PC366_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2577841.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALFNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLESKEIQDQLAKMYGKDK"
     gene            complement(27525..28544)
                     /locus_tag="PC366_002333"
     CDS             complement(27525..28544)
                     /locus_tag="PC366_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HDF2577842.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKEII
                     KSAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
     gene            complement(28541..29110)
                     /gene="mocA"
                     /locus_tag="PC366_002334"
     CDS             complement(28541..29110)
                     /gene="mocA"
                     /locus_tag="PC366_002334"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HDF2577843.1"
                     /translation="MINAVIMASGFARRMGANKLLLNYKGCSIIEHVFREVSKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANIGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDMCGNPVIFPYSKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKMDYERIGGKL"
BASE COUNT         9865 a         4707 c         2982 g        11649 t
ORIGIN      
        1 aatattacag tattaaataa aatctaataa aattaactat aaaatatcta ttatataaat
       61 atccactctt atgtttgaaa tctgtcatat agttttatcc ttcttatctt ttatatcaat
      121 aacttttttt aataaaattg acaaaacaaa gtaaaaaacc ttattgataa tgaaacaaat
      181 gatactataa gttctgatat tatagtaatt gcatataaat agacatcata acaataatat
      241 aatattgtca ctataaaatt aaatgtaaaa atctccaatc taactaaata cacatatagg
      301 tattttttaa gtttttaggt atttcttctg aaaatgattt attgattgat accaatttac
      361 ataatctttt taatataaac aatgatacaa tatatgggac agcacatatg tatatagcta
      421 cttatattac atattacagt tggcatattc gtatttgtaa tgcttatacc aattttaaaa
      481 tacaccatca gtactaatgg cattaaaata atctataata aagttaaaat tattccaatt
      541 agtacaatat tatttaatat tttacaactc atattctttt ttatataaat ttaccacctt
      601 atacattctt atttttagtg tatattataa tggttttata tattatatca acaatttatt
      661 attgaaattc aataaattat atattataat caataatata ctttatataa aggagatgat
      721 attttatgat tacaaaattt tttagtaata tattatcagt atttctatat tttctattat
      781 cacttttagg agttgctggt ataatattct tatgtatgat acctatgttt ttatatgatt
      841 ttagttctga caaagtaatc gctttaattg caagaatact atatttttct gactacttta
      901 tagtcatctt attcttgata tttataatta atagtactaa gtattcccca ttcatacttg
      961 aaaatgtaaa aaggtttaaa gtaatgggat gttgtttatt gataaacact ataattgaat
     1021 gtgtaattgg ttataactca aatactagtc ttataatgat atttggagat aatagtggcg
     1081 gtatctcacc acttatggtt atttctttta tatttgcact aatgtgcttt gtaattgcag
     1141 aaacatttga taaagctata aaaataaaag aagataatga tttaacgata tagaggtgat
     1201 gttatggcaa tagtagttaa cctagatgta atgatggcaa aaaggaaaat atcacttaaa
     1261 gatttggcag aaaaaataga tattacaaat gcaaatttat caattttaaa aactggaaaa
     1321 gcaaaagcta ttagatttac cactctaaac gaaatttgca aagctttaga ctgtcagcca
     1381 ggtgatatac ttgaatatgt agaagatgaa aatgattaaa aaagagtgtt tagaaacact
     1441 cttttttatt atactatatg atttttattc ttttactata ttattgacat taatattaac
     1501 tttgtttaaa gtcataacaa aatacgttct aagaaagaaa ctgttccttt ttctatttgt
     1561 tatccattac ctataagaac tgtatcacac taaatcatac ttttaaattg ataattttgc
     1621 cacagattcc tatatacatt cttttctacc taatatttat ttaaactgtt agcaaaacat
     1681 ggaacttttt catttactta tacctccatt tatattattg catagtttat agctacgtgt
     1741 tataaattac attattgatg atttatctaa catttgtaat cttttagata ctctttgaag
     1801 ttacaacact gttatactct aattaagtaa actaaatctg atacaagttg gtgattatat
     1861 gaaaagaaaa ctttcaacct attttaaagg atatatttta ggtttatgta tagcattttt
     1921 attatttact tttatattaa aaaaattaat tatagaaaat atcattggaa taataattgg
     1981 aactggaatt gcatttttac tgatttacct atttaataaa aaaagaaaat aatattctat
     2041 aaaaaggtct tttagtgaat ttacaaaaaa ttaataagaa taatatatac ttagtattta
     2101 aaaagggtaa caactctctc tagctgttac cttatatatt tatctatatc tttagtatta
     2161 agttttttaa tttctacttt tttaattatc aatttctgta tgtagatata ctaaaccttc
     2221 caacttgaga tttaaataac ttttcaatct cataaactat tctatacacc ttattttcgt
     2281 actctaaatc ataatacaca tttatttcac ctatactgtt tacacttatc gtataatgtt
     2341 ctttttctat tatacatatt cttccaaaat ctgacaggtc attatctatc aattttaact
     2401 gtttttttat ttttgaaaaa tctaatcttg gaaatatgtc attaggataa aaacttttat
     2461 tatatacaag catttcatcc accccttatt tattctattt atatcatttt ataccctaat
     2521 taataattta ttaatcatct ttttccatat tattcaaatt ctcttatata aaaacaaaat
     2581 caatttagaa tatgtattat taaatataaa gtgactcaat ctttatttaa taagaaaaaa
     2641 catttatatt acatataatt aatataaaac taatgaagtg ggtgtatgaa agagaaaaca
     2701 caattttaat ttacattcca tatagttaat ataaaacagt tgtttttatt ttttctaaag
     2761 agaaaaaact agactttaca ttccatatag ttaatataaa actttctgta tattttagtt
     2821 gtgttttaat attataacac tttacattcc atatagttaa tataaaacat ggcagtaact
     2881 aagaagaaaa ctataccttt tttattcttt acattccata tagttaatat aaaacgagga
     2941 aattttatac taatgactga tgctagattt aactttacat tccatatagt taatataaaa
     3001 ctattataag gagcattata cgaccaaaag ccaaagcagc tttacattcc atatagttaa
     3061 tataaaacaa gcaacagcaa gagtcgcgac aacattaaaa acttccttta cattccatat
     3121 agttaatata aaacctttat ttttttctct atatcgagtt cgccaaattc actctttaca
     3181 ttccatatag ttaatataaa acagtccagc gttgtgtggt cgtaacacac caatcctact
     3241 ttacattcca tatagttaat ataaaacccc aaaataaatt aagtatttcc aatacttata
     3301 catatacaat tctcctaaac ttgcagtgag cgagcaatag tgcaattgat aacagttatc
     3361 atacactctc aacgctttat atttcaacta ttaaacccta ctttatcaca aaaatcgctc
     3421 actgcaaaac ttttatattt ttattatatc ataaaactca tactataaaa taaaaatggg
     3481 ataattttac aaactaaaag catctacatt cttataagta tttattatat tctctattcc
     3541 aatgattcct ttttcttttt attgcatcct tcctatgtaa tcgcacttta gctcaacaag
     3601 tcttttattt tcattaacaa ttttttaaac tattcaaaat catcaaattt ttcatcttat
     3661 acagttaaat caaaatacgt gttatatctc tttatctata tacttttctt ccttccattt
     3721 ctttttctct ttctacattt tcactttgtt actttacaat ctcaaggtta ttatctgcta
     3781 ttaaagtttt atctttccag gtttcacaaa aataaattga ataagtgcaa aaataacaga
     3841 tacaaaacca taactatttt cttttctata aaaaaatata tcatcaacaa gaaacataat
     3901 aaatgaaaat aactatgaat aaatactctc atttagaaga aatagacaaa gatattcctt
     3961 aaaatttaag caaaatattg tttaaataaa aaaactgact gtcagttaaa tgccagtcag
     4021 ctattttata tattttatcc aaacatcact atatttgaac attttaataa ttaataatac
     4081 ttattaatat acaaacttta ctcatacaca gaatatcttt tccaaatttg ctctaaatca
     4141 tcaaaatgct gtttaatatc ttctttttcc ttcattccaa cagatatagc aagggcattt
     4201 gaaatactaa gagctggaac tagagaatct acaaatgaag ccatattact cttaactaga
     4261 agagtgttat ctgcaagtga tgctactggc gcaaataagc tatctgttaa tgatattaca
     4321 tgggctcctt tttctttagc ataattgaca atttgataag atttcttaga ataacgaggg
     4381 aaactaatag caactattac atcttcttca tttattctta caatctgctc aaaagcatct
     4441 cccatatcca ttctaattat atgaacattg tcaagtatta tatctaagta aaaacctaaa
     4501 tattgagcta ctacaaaaga actcctcatt ccaagtatat atatttttct cgctcttaaa
     4561 agtttgttag aagcttcttt aaacgctctc tcgtcaattt cttctagtgt agaccttata
     4621 ttatctatat cactttttaa aactttgttt agtattgcaa aatcatcgga ataatcatgt
     4681 gccatttcaa ctctttgtac tgtagttagt ttatttttta tgagttcttg aagtgcagct
     4741 tgtaatttag gatatccact ataacctaat gcatttgcaa atcttacaac tgtagactca
     4801 cttactccta cggtttcacc caatttacat gcagtcataa atgcaacttt atcataatta
     4861 tttaaaatgt attgtgctat aagtttttga cccttactca atctcgtata ttgagattgt
     4921 atatttgata tcaaatgttt actgtccttc atttcatttg tttcttccat ttttttctcc
     4981 ttttagttat ataaactatt ttgttttatt aacactgtct ttttctctaa aaattttatt
     5041 ttttatctca atttcatctt agtttttatc atagcttctt aaactcataa aattctaact
     5101 tttctgtacc ttatacttca catagtattt tcgattaaat ttattatacc atctttcctt
     5161 gcatttttta atatttatcc aatatttctt ttaaattttt caatttttac tcatttaaaa
     5221 gttatctatc ttattttgca tatttagatg tatattttgt tttgagaata agctgttgta
     5281 tacttattat ttaaagtatt tttaataggt cacactatat atattaactc ttaatagaat
     5341 cttgtcaagt tttttagtat ttattatgct tttttctttt caattaaaat caattgtggt
     5401 gggttattga cttgatttaa aaacttagat tctaaaacat taaattcatc ttgatttaaa
     5461 ttattgacaa ggttatatat gcaatctttt tcttcttgac ctccatcatg ccctgtatat
     5521 atggcaatgc ttattactcc attttctttt aacatttcta aacttaactt tatagccttt
     5581 aaagttgtat ctggtttggt tataattgaa tgtttcgctc ttggaagata acccaaatta
     5641 aataaaacac atgaaacttc ttcttttata tattgattca ttttttcatg cccatcaaat
     5701 atcaacttta ctctatctgt atatccttct ttctctagtt tctttcttgt agactttatt
     5761 gcttcttctt gtatatcaaa agcatataca aagccctttt ctccaacctt ctcagctaga
     5821 taccttgtat catacccatt tcccatagta gcatcaatta ctatgtcccc ttcatttata
     5881 atattttcta aataaaattt atttatatct gtaattttag ttaaatactt tgcatatgcc
     5941 ataatactat ttctccctac tattaacttt atttcatttt ttctcaattt atttttatct
     6001 tattttattg attttaaata ttttatttca tcttctgtta ggtatctata ttctccaact
     6061 ttggtgtctt ttaatactat tttccccaca gaaatccttc ttaaatttaa aactggatga
     6121 tttatagctt tgcacatttt tcttacttgt ctatttctac cctcatgtat agttatttca
     6181 cacactgaat aatttttttc tttattttct ttagttaccc ttattttggc aggtgccgtt
     6241 gtgtaatctt ctatttttag tcctgtttcg aattgtctta tctcatcatc acttataatt
     6301 cccttcacac ttgccacata cgttttatca atttcatgct ttggatgggt aagcttatat
     6361 gttaaatcgc catcattagt aagtattaat aaaccactag tttcataatc taatctccct
     6421 attggatata ctctttccct tacatcttta agtatgtcta ttacactggg tctattgaat
     6481 tggtctttta ctgtagttat atatccctct ggtttattta atactatata tatataattt
     6541 tcacttggtt ttactttttt attatcaaat tctactatgt ctttttcttc atcaatatta
     6601 aaagataact cttttactac acttccattt acctttattc ttcctccaag aattatttct
     6661 tctgattttc ttcttgatgc tattccacaa gaagctatat acttattaat tctcatactt
     6721 aatccttcct tatcttaaat tatgtgtgtt taatattttt atcaatgtta attttgctac
     6781 attattatac tatactagac cttaattaaa aacaagcaaa aaaattattt aattttccta
     6841 aataattgta atttcttttc acatactatt aatatgtaat agctgactaa acactatttt
     6901 aaggaagtga ttattatttt aaaggaaaat ataaaatatt atttaatagt cgtgtttatt
     6961 ggaattttat tttttaaatt tattaatact ccatcaaact ttatatctag tattgaagga
     7021 ttcttaaagt tttttagccc atttttatta gctattttac ttgctttact tttaaatcca
     7081 cttgtgatgc tttttgaggt aaaattcaaa gcacatagac ttttagccat ttttttatct
     7141 tatatattta taggttttat tttagccttt gccattaggc tattaattcc atcaatagct
     7201 aatacattaa atagattgat aaatgaaatg cctatgtata ctgattatat agatagtttt
     7261 atagaaaaaa atatgtcaaa catagatttt ctaaaaactt taattcctca tatacaacat
     7321 agtttagata atttattaaa agaagcaagt aattttgttg gtaaaattcc taaaaacttc
     7381 ttaatctata cacttagtat atcttctatg ctatttaata tgacaatggg atttatacta
     7441 tccatataca ttatatatga caaagaaaaa attgcattgg gatttaagag atttctatat
     7501 tcttctactg ctagaaacaa ggcagataac attatagaat tttttaggac tactcatgat
     7561 attttctatg attatttact tggtagaata ttagactctc ttattattgg tataattgca
     7621 tttttaggat ttcaatttgt tatcagaata gaaaatgctt tatttttagc ttcaataata
     7681 ttcttaggta atataattcc ctattttggt ccttttattg gtgcaatccc tccaatagcc
     7741 atgactatat tatatagtcc acaaaaaact atatgggtca ttgcatttct atttatattg
     7801 caacaattag atggaaattt tatagaacca aaagttatgg gtaatcaagt tggtatagga
     7861 gctatatggg taatatctgc tattttggtg ggacaatctc tatttggttt cataggagtt
     7921 tttctttcag taccaatagc tgctgttgta aaaacttatg ttgataaata tatagataat
     7981 cgtttacaat agcttatctc tactgtgact ttaattttta gtttaaaatt taactgttat
     8041 ttattaaatt atttctcaaa aaatatctct tagtaagaaa aaattgctaa gagatatttt
     8101 ttataatata taatttgttc attaaattta tgcatatatt ttatacttat tgattatttg
     8161 agttttgaga atttccacca ctatctgaac caccagtagt atcttgtgga gttggtgctg
     8221 gtgttggatt actattattt ggcttttctt gattttgaga agaactgtta ttattgtcag
     8281 acttattact atctgatttt ttatcattat ttttagaact atatttatta tttttactac
     8341 ttccactata agaagatttc cttgcatctg attcaactct atacctatct tctccagccg
     8401 tatcttttgc ctttttcttt ctttgttcct ctgcttcgtt ttgttctttt tctaatttag
     8461 ttaactcttc tttcttttta gttgcctctt ctttaataac agaggaacca tttttgattt
     8521 tctctataag tttaagttcc ttgattgcac cctcataatt ttttaattct tcaaactccg
     8581 tcatatttga cattctcata gcttgcatat acatagctct tgcattctca ttagtactat
     8641 cttcttccag tgcagaggat aatgattcca tagctttttt atagttatgt ttttctaaat
     8701 atgtttttcc ttgctctact aaatttattt catctttttt attaaatgaa catcctacaa
     8761 gaaatataga taatatcgat attaataaaa ttactcttcc tctcattaaa tccctccttg
     8821 tcatatactt taaattttat cataattata aagtttttaa aatattttat atttattaca
     8881 agaaatttgt tagtaaaaca aaaaataagc agatatgcta cgaacgatac aataaaccaa
     8941 aaattaattt agagatacat atcctagcaa atctgctcat aataaacttt aatatttaat
     9001 ttttattata tacttttcca ttttatatct ctaaagctaa taagtcctca tagctttgtc
     9061 tcttacaaat tatcttatca tttccatcaa atactgatac tactgctgct cttggtattt
     9121 tattataatt tgaagacatt gaatatccat atgcaccagt tgatgttgtt ataagtatat
     9181 ctccactttt aatatccatt atgtttatat ctccaattaa tatatctcca ctctcacaac
     9241 attttccagc tattgttaca tgattcatag cctcatgatt aattttattc acaatactac
     9301 actcataact agcttggtac aacgaaggtc ttacattatc tgtcatacct ccatctacac
     9361 ttacataaac cctaacatct tttatatctt ttatagaacc tactgtatac aatgtacttc
     9421 ctgcatttgc aactattgat cttcctggtt ctattaccaa tgtaggtact tctattccaa
     9481 gctctttaca tgaagtttct gctttagtga ttatggtttc acaaaactct tttatagttt
     9541 taggtttatc tccttcgcta taataaacgc caactcctcc acctaagtca atttctgtta
     9601 gttgtatgtt gaatttttct tttatttctt ttaccaagtt catcattata tccactgtat
     9661 ctatgtatgg ttctacatca aatatttgtg aacctatatg agcgtgaaga cctacaagtt
     9721 taatattttt atattcactt aatttttcta ttgctctaaa taaatctcca tttactaaag
     9781 caaatccaaa tttagaatct atctgtccag tttttatata atcatgtgta tgagcttcta
     9841 taccaggagt tattctaaag tatatctctt gagttttacc tttatcttca cataatgctt
     9901 caagcaaatc taattcataa aaattatcca ctacaaattt acctacacct aaatctaatc
     9961 ccatgtttat ttcttcttta gtcttattgt ttccatgaaa gaaaactttt tccataggaa
    10021 aatttgattt ataagctgta tataactcgc ctcctgaaac tacatctaaa cacatttgtt
    10081 cttcatttat aagattacac atgtaaagag gtaaaaaagc tttccctgca taagcaacct
    10141 tattttttcc ctctctagcc ttaaaatatt ctatatattc tctacaattt tgtctaacta
    10201 aagcttcatc aaatacataa agtggagttt gatatttttt actaagttct aaacaactca
    10261 ctcctccaat atataattca tcattattta cagtcatagt tccatgaagt ttcataatag
    10321 cctccccaaa ttttatatat taaatacttc tgctattttt tctatagcta cttgcttatc
    10381 atcagaattt atagcacaag ttatacgaat ctctgatgta gttataagtt ttatcattat
    10441 accattttca ttgaatatct taaatacttt agcagcaact ccagaagtat ttttcatacc
    10501 aagacctact aaagaaaatt tagtgatatt attatcaatc actacatgtt cttcatctgt
    10561 atatttagat actatctttt tacattctcc caactcttct tttggaactg taaatgatac
    10621 acttatctta tctaaaatag gtgcagtttg gcttatcata tctacactta tacctatagt
    10681 tgctatatct tcaaataagc tagatatatt ttcagcttta aaatctttta ttgttataga
    10741 actgtcatca tcactagtag ctaatcctgt tattacttta tcctctaatt tcatgtcttt
    10801 tccccctctt atatatgttc ctttttctgt accacatgta cgtccgacat agatttcaac
    10861 accatatttt tgtgcaagct ctatacttct tgaatgcatt acttgtgctc ctaaactcgc
    10921 taactcaagc atttcttcat attcaatctc atcaagttta ctagcctttg aatattttct
    10981 tgggtctgta aaataaattc catcaacatc tgtatatatc tcacattttc catttaattt
    11041 aaccgcaaga gctacagcag acgtatctga accacctctt ccaagagtgg ttacatcacc
    11101 atcttcgttg attccctgaa atccagttac tatcacgaca tttccttcat ctaaactatt
    11161 tttaattctg tttacgttta tatcatcaat ttgagacttt ccatgaagac cactcgtttt
    11221 tatatttaac tgataagcat tataacttat agctttacat ccaagtgcat ttaatgctat
    11281 tgataataaa gatgctgaaa tcatttcacc agtagacatt aaagcatcta attccctctt
    11341 actaggttca ttactcaatt cctttgctaa agttatatat tcatcagtgg attttcccat
    11401 ggcagacaca actattacca tttgtggatt ttcttttctt cgttctatta tattttctgc
    11461 tattgatttt attttttcag tatctgctac tgaacttcca ccatattttt gaacaattat
    11521 actcatgctt tctccccctc aagctaaatt ttgataaata aaaacgccca aaggtatact
    11581 ttggacgtgt aaatttcata gaccaagtaa ccttgtagct caccacttta aaagtgacag
    11641 ccttatgcat attctgcata agtccagaaa atttgtccgt caacaaaatt tcttcggcta
    11701 tatacccttt catcaattat caatgcttac cagctcctat tgaatactat tgaatacagc
    11761 tacctctacc ctaggctcat tatttttaat taatttatta atatagtttt atcatattct
    11821 atataatatt gcaacaatta ttttacaaaa tgtggcaaat cgatagtttt cttttctaaa
    11881 gttagcttat atacaattaa atagtttatt taatcctaaa tctataaaat ttatgctata
    11941 ctcattatca tatctctcta aatcatttaa ttcggataga ttatctggtg taactaccaa
    12001 aacgtttggt actttaaaaa atggaattgt agatttatct atttttttag aaagattttc
    12061 gtatttagaa atgtctattt cattatttaa gtcaacatca actaaaactt gctttatatt
    12121 accaaattgg tctgtatatt caataaataa atcgtatttc acatcatcta cactaacatt
    12181 tcggtaaaat ctttttacat cacaacctgc agtattgatt ctaacaacta attctgatcc
    12241 tactagagcc tttattaaat catctccctt aaaaagttta ctaccgttta aataatatac
    12301 ataagagagg tctttataat tataataatc cacatcacaa ggatattttt ttagtgtata
    12361 ttcactacac atttttctca aagttttttt aaaatttttt ttattgtatc ttttttggtc
    12421 tccataaatt tttctaaatt gagactctgt aacacatcta accctgctaa ttaaaagtaa
    12481 tatctctttt tccatattcg tcatagtaca ttctccttga agtattattt gcaaagttgt
    12541 actaatatta tattaatttt atgacattaa atttacaaag aattaaaata aaatagctaa
    12601 tttttataga attaaattct ataaaaatta gctatcacta tgttaaatac tattatcaat
    12661 ctttttattt aaattataca ttaccttgat tttcagaatc tttggaatct gtattttcat
    12721 cagttcctgt tttttctttt gcttttttat cttcaaagtt tgcaatattt aggttatcaa
    12781 attctgacat ttctattaca ccagattctt cttttgaata cgatattttg actttatcac
    12841 caacctgagt caatggcaat tcgctagata cttttgaagt agccctaaat attatatctt
    12901 tatttgaatc taaagttaca taataattag tgttaccacc tcgcacatct gggcttattc
    12961 ttgtcactgt gccttctaat acctcatctt ttaaatcatt atcaagtttt aaatcattac
    13021 ccttagattc taatgcatcc ttatagtttc ttaatgcttc attcttatct tcacctattc
    13081 caagtacatt ataatcttca acagatacaa atgcaactct cttaacaaga ccagccttat
    13141 cttttaatga tgatacatat gttggctgac ccaatatatt atacattaca gggaacgtcg
    13201 cttcataatt tttttcttga acattacctt cagctgattt cattgcagcc gtttcagtag
    13261 ctcctggttg tttatataat ctagcttctt ttgttctaga atcaactaac ataaatccaa
    13321 ttgtagattc atctccacct gaagatgtta tacctgtata ccaataagac ctgttatcat
    13381 tgccataaac taatgatgta ccttctgttg gtactaaaac tcccttttct gatataacag
    13441 agtttaaaaa tccattaaca taaacacccc agtctttaat ctggtctgtt acaaagcttt
    13501 gtggttgtat tctatccacc catttaggtg tgtttttaac atcataaaca tttatttttc
    13561 cagtttctgc atcaacagtg gctattcctg ttgcatttgc tcctccatag ccaattttat
    13621 gttcatataa acttacaacc caataaggtc ttccttcatc atttatttca agagtgaaat
    13681 ctgtcatacc aacatttaca ataccatgta tgtataaatg tctttgtaaa tcctgatgta
    13741 agtaggcttc tggttggtaa actatcttta ttggctttcc atctatttct tgaactaatt
    13801 ggacgtcttg aggattacta gctgatactt ttacataacc acttgtacca cttagagatg
    13861 ttatccattt aattatgtct ctgtgaacaa gaggcgctac ccagtacaac tctccatcta
    13921 cattttgtat atgaaatttt cctaatttgg atacactccc tattgcagga acttctccaa
    13981 gctttttgtc acctaatttc attgccatat cttcatctac aagacgaatg tcatttacac
    14041 tgacagggct aatgtcatca gtaaatttac tttcagttac ttttcccaat agttctctat
    14101 atgattttgc atgaagtaca ggtgtagaag ttataaaggg aactactaca atatacacaa
    14161 gcaaagctat tgctattgaa aaattatatt tagccatttt agatgctctt tcatttctat
    14221 ctaacatcat atctagtatt cctgctacaa caaagaaaat tattcctact gaaaataaag
    14281 atgtaaaatc taatcttagt acaggtaatt taataaatgc ataaattatt acaattatta
    14341 atgcaactcc atatgtttta agatatcgtt tcatttaata ctcctctcta aaaaatgtta
    14401 ttattattat tatatccata tatttacaaa aaataaatat ttatcatatt tattatatat
    14461 taagatatct ttatatattt atagttctgc ttattcaact atatttaaca ttatacgtgt
    14521 atgtataaat actttttata cactgtttgt gctatccatc ccgcacctaa aggagtggga
    14581 tttttgcact attctgtatt atatatatcc aaaaatatta taaaaataca aatattagca
    14641 gaaatttaaa aactgaagaa agtattctaa ctaagattta caaattctta atcctatcga
    14701 agttaaacta ctatcttcag cctaattatc tagcaatatt tttttatatg aaaaactcta
    14761 aatcaagttt ttaaatgttt gcgatttttg atacataaga atgttgtcta gaattatatt
    14821 ctgataataa accttcatac tctaaggtta agccagataa attataaaaa tcatttggcg
    14881 ttacttcaaa tgcttgttta tttaaaatgt ctatctcact tttttctaac atgtcagcaa
    14941 caaagtttga acatacatat ttatattcag attgtctctg aatattcatt agtaaatata
    15001 ttaatgccat tgtatcgtaa tagtaatctt ctctataatc actaattaat tttatatttt
    15061 tatatagatt ttcatattgt aaattatcta cttctaacga atatacccta cacacagtgt
    15121 tttttcttat agcatacaat ccttgattta tattttcttc aacaaatcct ccaataaatg
    15181 gattccttgg atttagcctt ccaaaagaat acattggttt tagattttca tttaatgata
    15241 ttgacacatg tgtatacagc tttttactta tattccttat taagtaagat aatatagttc
    15301 ctgtatatgt tgttacaata tagactttat tcatcatttc cccccaatct agtaactaaa
    15361 tgatattata cacttacaat ttaatatcat aagatattct aacataataa atgtggtttt
    15421 acaaattttg attttaaggt actttaatat tatataatat aataaaaata taaatataag
    15481 ttttctatat ttttaaccaa cagatgtttt cttcaaatta atcagatgat ttagtatatc
    15541 ttgaaccttt ccagagtcct ttaaatatcc taatgcccca tttatttgtg attttaaatc
    15601 tatttctact tccatatcca aatcaacatt tccttttttt atagatatat ttttaagtgt
    15661 tattgggtaa agataacttt tttccaaagt aatcttattt ccattaacct caaatggaac
    15721 ttttttattg tagttactta atattttttc tagcatttta tcacttagtt taaattttcc
    15781 aattttcaca ttctcaagac ttacaactaa gtttccatcc tttaaagtag gtctcaattc
    15841 aagttcatat tgactattta ccaaaccaaa taccttatat ggtcctgcta cctttatttt
    15901 accatttttc atttcaacaa aattattttc aagttcatta attccatgct tctgcatcaa
    15961 tgtatatatt aaatttttaa actcttcctc tgaaacagat atttttccaa ccattctaag
    16021 tggatttttt actacctcca tagaatttat atatgagcct tttgataaat attcttcatc
    16081 tatgatttta ttattttgtg aactaacatc atatctttct tttggtgtca agatatatac
    16141 aacaattcct gcaagtacta aaacaataac aattaaactt aacaaaatct ttgcaacctt
    16201 tcccataatc gtctccttta caaatctgtc atcagattta aaataaattt agataactaa
    16261 cttcacataa tattcttaac aatatacata ctataataca gtcttttaaa aattaattca
    16321 accaatctaa tgttttgtaa ataaactgta aaaacatgtt tttagtataa aagttaatat
    16381 tttgcataat actcttaatt acacctttat ttttttctaa tcttggatta aaattaatat
    16441 tatgcaatac agtgtagtgt tctgtattat aatcaaatta aataggaggt atagaatatg
    16501 tcaaatgaaa cgaactcatc taactttata aagaatatta ttataaacga cttagaaaca
    16561 ggaaaacatg acagtatcat aactcgtttt ccacctgagc caaacggata tttacatatt
    16621 ggtcatgcaa aaagtatatg tcttaatttt ggattagcta aggagtttaa tggaaaagct
    16681 aatttaagat ttgatgatac aaacccatta aaagaggatg ttgaatatgt agagtccata
    16741 aaagaagatg taaagtggtt aggatttgat tggaacgagt taaattttgc atctaactac
    16801 tttgatgaaa tgtataagag agctttaata ctaataaaaa agggtaaagc ttatgtatgt
    16861 gatttgacac aagaggaaat gagagaatat cgtggtactc taactgaacc aggaaaagaa
    16921 agtcctcata gaaacagaac tattgaagaa aaccttgatt tatttgaaag aatgaaaaat
    16981 ggtgaattta aagatggtga aaaaacatta agagccaaaa tagatatgtc ttctccaaat
    17041 ataaacctta gagacccaat tatatataga atatctcatt caacacacca taatacagga
    17101 gataaatggt gcatatatcc tatgtatgct tttgctcatc caattgaaga tgcaattgaa
    17161 ggaataactc actctatatg tactttagag tttgaagacc aaagacctct ttatgattgg
    17221 tttgttaaag aatgtgagat ggaaaatata cctagacaaa tagaatttgc tagacttaat
    17281 ataaataata ctgtcatgag taaaaggaaa ttaaaacaac ttgtagatga gggtattgtt
    17341 gatggttggg atgaccctcg tgttcctaca atatccggaa tcagacgtaa gggatatact
    17401 gcagaagcat tgcgcaattt ctgtagtgaa ataggggtat caaaagttaa ctctacggta
    17461 gatagtcaaa tgcttgatta tttcctaaga gaaaacttac aaccaaaggc tcctcttact
    17521 atgggagttt taagaccttt aaaacttatt ataactaatt acccagaaga taagattgag
    17581 atgcttgaaa tagagaataa tgctaaagat gaatctcaag gaaagagatt agttcctttc
    17641 tctagagaat tgtatataga acaagatgat tttatggaag aacctgttaa gaaatatttt
    17701 agatttttcc caggaaatga agtccgttta aaaggtgctt attttgtaaa atgtactgat
    17761 gtaattaagg atgaaaatgg aaatgtagtt gaaatacatg gtacttatga ccctgaaact
    17821 aagagtggct ctggctttac aggacgtaag gtaaaatcta caatacattg ggttgatgct
    17881 aaatcagcta taccatgtga atttagatta tttgaaccat taattcttga tgatatacct
    17941 gaaaatgaag gtaaacattt cttagaacaa ataaatccta attcattgga aatattacaa
    18001 ggttttgttg aacctacaca gataaaagat tctaaacctt ttgataaatt ccaatttgtt
    18061 agaaatggat tctttagtat agataataaa tatacaactg acgaaaaatt tgtatttaat
    18121 agaatagttc ctctaaaaag ttcttttaaa ccaggtaaat aatcttacaa tcaaaaaatg
    18181 aagacttaaa atataaatta cttctactat aaataaactt agttagaagt aattttttat
    18241 ttgagtcttc atcatttact ttaaatgatt aacttttttc actacagatt cccataactt
    18301 ctattccatc ttttatgcat tctatgttaa gaggaaaatc tggtcctttt tctccgtcaa
    18361 tatctgttat aagtgaatct tcacattcta tatgcacctt tttagtttta aagtatagta
    18421 tttcatttcc attatattga tctaaataat cacctctaag cacacttatc aaaactggta
    18481 ttgattttgg tattggcatt cctttaaaaa taattacatc caaatatcca tcatctattt
    18541 cagccttata tgctagattt atatttcctg ctgttttgcc attaaaaatc aacataagat
    18601 acatatctcc atcataatac atttcctcag aagatacttt tatcttaaat ttcctcatat
    18661 acaatgcttc ttctattccc tttatataat aagaaattct tccaaatgaa ttttttaagt
    18721 ctgtgtttat cctttgtgat acatctgtaa acataccagc acttgcaaca tttataaagt
    18781 acttattatt gactttccct atgtctattt tctttggttt tgaatttatg atttcattta
    18841 tagcttcttt tatatcaaat gaaatttgaa gagcatttga aaaatcattt gcagttcctg
    18901 taggcaaaat tccaattgga atttttatgt ctaattcttt cattgcattt actactaaat
    18961 ctacagtacc atctccacca gctatcaata tgtgttcata agaactatca acttccttaa
    19021 atgcattctt tacaggttct ttaatagtta atctataggg tatcaataaa taattttttt
    19081 cttgatataa ttctatgata gtgtctaaat ttgataatat ctttttttca cctgaattag
    19141 gattgtatat aagttttact tttttcatta tttctcctta ctcattttat tcttttagta
    19201 tccaaaatct tcatttaaaa aaatcacatg tattctttct ggtgttaatt gtctttttat
    19261 aagtgtataa ctacagcata ttcttcctgg acttgaacag tctatacata taccagtagt
    19321 cttacatcca gtatttgtac ttaatctttt acaattggct ggagcagcta ttgtttttgt
    19381 tctttttata gcttcatcta catctttaac tattttattt actcctgcta taactattac
    19441 tttatcaggt ccatatatca tagcagcaac tctattccca ttcccatcta aattgtaaag
    19501 ttctccatcc tctgttatcg cattagtact tgtaaaataa gcatctgcag aaaatgactt
    19561 tctatatatt tctttcattt cttctggttt gatatctttt gcatatctat caagaaaatt
    19621 atatttttct cttataaaat caatcactcc tgtttcaaat aaggtcatag aacctccaca
    19681 tcctactaga gaacctactt taactatttc ttcaattttt ttaagaagct cttctttgtt
    19741 acttactaaa taccctttca tattattgtt ttccagagat tttattgttt tttctattct
    19801 tttttcatta agccaattta aattttgatc cattttaact tcccccttat ttttaatatg
    19861 tacttaatta tttataaact ttattgtctt tataagttta ttttagtaca tctaaaaaaa
    19921 aatacaatat aaaacttaaa tagttttata taattttttc caaaataact tactcaatca
    19981 aaaaaggaaa gtagatgtac tattctactt tccctatatt gtatgtagta tttattgcct
    20041 aaaatctata tattaattat atgtttcata ttatataata tcacagttaa ttaaaatgta
    20101 atactatctt ctttttaaac atataaattg tattattaaa tttaatatat ccaacttcaa
    20161 taaatcttat taatttgatg aagaagatgc tatagctgca cttgttgctg ccattacaca
    20221 tgcaatttga atagcaacaa caatatttaa aaatatatta ttagttatag agcctatatt
    20281 attctcattt cgtatcaaat ctgcataaat tgaagctaca atagcagaac taatcattac
    20341 tctattactt tttcctaaag accaatttcc aaagcctttt tcttctttaa gtttatttga
    20401 aacatttttt atctcttcta ttatttcatc ttctctataa tctaataatg aaattgctcc
    20461 tattattgga tatccataat aattcatttt acaatcattt tctttaaatg cttttttaag
    20521 ttcaatagtc tttttacatt taagcatagt tctatcatca ctaaataaaa gaatttggga
    20581 taatgcttgt aaatcatttc ctttataaaa accattttca tttagaaatt cataacattt
    20641 ttctatgtat tctaaatctt catctaaatt ttttgaatga attgcaataa gtgctatatt
    20701 acaatagtca tcactagaag ttagaaatgg atgttttttc ctcatgtaat catatattat
    20761 tttcattttt gatatacatg taagataatc cattttctct ctattttcat aaactattga
    20821 tgctgtaagt ggtaaatatg tatcgcccca aaacttttca cttttaagtt ctttgtatat
    20881 atctaaaatc atcttaaaac tactttctgg atttgattca aacgaaagta gtgttgccat
    20941 ataaaacata ttatatcctc taaaattaga gaataatcca gtattttttt taataagctc
    21001 tattcgttct tccactaatc taggacttat tctcttgttc ttaagagtaa atgcaagtgc
    21061 acaactatgt tgtatcaatc ccatttgcca agaaccttta acttcattta atgctttgta
    21121 attttctatt aataagttta cttttccatt tataaacgat tgttccatat tgccctccta
    21181 gtaatatatc tcattgtact aatagtttta tatttattat atatatatta aatactacaa
    21241 tcaatacata ttacttcaaa gaacatcatt cttcaacaat aatgtagcct tttttgtaat
    21301 gtcttcccat attattgact ctatcatagt actctgattc actttcatta ctccatttgg
    21361 gcacaaatac atctattgca ttagaattac taaaatactt actagacccc ctatccataa
    21421 cagtttttaa ttttccatct acaataatct tagttccaaa actcaagtga ttgtttgcta
    21481 caaaaccatc ttctaaatca tctcctgtag cagttatcgc tccatatcca ttttcttgat
    21541 taagacttgt gtaataacta acttcaaaag ttataggtac taacttcttt attttaatac
    21601 ctaactgatt ttgtagtttc tccttttgta ctttcaactt atactcatca ctatttttat
    21661 aatcttccat accttgatta tacttggaat taaagctttt acctgacttt actatagtat
    21721 ctatatttac tatagattct ttacaatgat ctgcatctat ttttgtttct ccatttacca
    21781 ataatggagt taaacataca ctacatacaa cacatgtaat caatgcttct ttaagcttca
    21841 taaattcccc ccttattatt ttgatatatt agcatattta atattatatg tctatattta
    21901 gatttaaata ccacacccat ttgctttaag aagttgtctt atatttaatt caccttaaac
    21961 acttataaat cctctatctt agaatcatat agaataaagc ttttatcgtt aaatattttt
    22021 tattaatctt ttaaaatcta aagctacttt atttaatttt ctctttttta gaatttaaga
    22081 attaaaattc tataatttta aaacatattg aatttatttt tttgagatga tataattttc
    22141 ttaagaggtg gttgatatga taaaaaatac aaaacaaatt acagtagaag ttaatgaaat
    22201 tttattacaa gaaatatcta agataactaa tgacgaaaat aatattttga cagatttgat
    22261 aaatgaatca attgtaaatt atattcttga aaacaaaaaa cataacattg aaaataaaga
    22321 tttagaagaa gtgattaaat tttacaaaaa agaaaatact gaaaaaccta aaagtgcagc
    22381 aagagctata gctgaagcaa aaactcatac cctgtattaa tcaaataaaa aagttcctaa
    22441 aaactaggaa cttttttata ttaataatta ttaatatatc tcaatattta tctcaaattt
    22501 atcaatataa gcatgtttaa tacaatctat tgtatactta tcttacccta gaaataatca
    22561 aaacaaaaat tatgcccttt atatctaaca attaatttac atgattaata tacaaaaatt
    22621 ctgactttta aattcgtata caatatcaaa ctaaaataat actaatgaca aacccaatat
    22681 aaattaaatt caaacaggtt tgattttaca tcaaacttat tgtattaata ttaaataaca
    22741 agacaaaata tttataaaaa ttacaaattt tacataaaac tttatatttt attcatttaa
    22801 ctaattattg taaaaactat ttattttatg ataattaact acaccaaatt attcatcttt
    22861 tttaatatct ttaacccatt tttcaacaga gttcaattct tcttcattta cccccttttt
    22921 gaacaaggat ttcataaaac tctcaataga acttccatgc atattatcta aaaaagtttt
    22981 tgtttcaaaa tgtaaatact cttcttctcc aataagaact gtataatgtg tatgtctatc
    23041 aatctttctt gcacttaaga attgcttatt tactaatctt gataaaagtg ttagtgttgt
    23101 agtttgcttc caattatata gtttttccat agcttcaatg acatcttttg atgctactgt
    23161 aaaatctgaa ctccaaataa atttcatgac ttttaattct gctggtggta tcttagtaat
    23221 agtcatatga ttttacactc ctctcaaact tctacataat taaatactat attaatagac
    23281 ttttcgagtc aaaggtttta tttaaaatat ctcatccaaa tttattaata caaaaaattt
    23341 atatttttat tcaaaattaa acacacaatc tattaatata aagataaata tctattctat
    23401 aagtataaca gattatcaaa ttaaaattct aatatttgac ataatatata cattttttaa
    23461 ataaatatat acaatgtatt aaaatgtatg caactctatt tcaaaattat tttgtgatat
    23521 atatatgtta taataaatgt ataaaatttt gattggtggg ttatatatga atgcatttat
    23581 tagaaaaaga aataaaaact atgttgttta cctggaattt gaagatgaaa agacaggtaa
    23641 aagaaaacaa aaaaatatgg gtacttttga taaaaaaagg gaagcaagta aaagactaaa
    23701 tgaggtaaaa gaaagcttat ataatgatgg ttttttagta ccaagcgaaa ttacagtgtc
    23761 agaatttcta ttagattttc taaataaata tagtgaaaat atatctttag ctacatataa
    23821 taattatgtt agtatttgta aaaattacat taatccatct attggaaaat ataaaataca
    23881 agacttacat ccggttcaca tacaaaacta catagataaa ctatcttata aactaaatcc
    23941 tcaatcaatt aagattcata taaatatatt gaaacttgca ataaaaagag cttatagact
    24001 caaattaata aaagaaaatg ttatggatag tatagaggct ccaagatata aaaaatttaa
    24061 aaatgagatt tatgatagag aacaaatgat aaaattatta gatttagcaa aaaatacaga
    24121 aatggaatta cctattaatt tggctattgg attaggtctt agaatttcag aagttttagg
    24181 tctaacttgg gataatattg attttgaaga aaatacaata acagtaaata agataacttc
    24241 ccgaattaat ggttctgtta ttctcaaaga gccaaagaca gaaagctctg ttagaaaaat
    24301 atcttctccc aaagaattaa tgtctttatt aaaagaatat aaaataaaac agaataaaaa
    24361 tttattaaaa tcttccatta gaaataataa taatttgttg tttttcaata agaaatgtga
    24421 acctattgct gaagatgtta tgagtaaaaa atttaaaaga tttttagaaa agaatgaatt
    24481 acctcatatt agattccatg atttaagaca ctcacatgtt actttactta taaattctaa
    24541 agtacctata aaggttatat ccgagagagt aggacactca aatataagta ctactctaag
    24601 cgtttattct catgtactta aagaaatgga taaagaggct tctgacaaaa tttctgaaag
    24661 tttatttaat gctaattaat attaatttat cttagcttta aattagctta gcttattgag
    24721 atagattcat taatattaaa tgtatctatc tcaaattaat aactacttaa ataatctgtt
    24781 ttattttaat ttatcgcctc agttattata cttttttatg aaaaattata ctttacaata
    24841 aaaaagatat ttccttatag aaagtatctt tttaaatact attttattat atacttgcta
    24901 acattggaat atctaacatc ttcttcatta catcatctac tttttttgct ttatattcat
    24961 tgtatccaat taaatatcct ttttcatatg aactttttaa aatctctttt tcatataaat
    25021 tatcagattt ggcttctgtg acacttaaat tataaagccc tttacaccca tcttcataac
    25081 ctttattata ccctttttct gcaaaatagt ttttatgatt tttttcgtta tgtactgaag
    25141 atattgttac tccagaattt tcttttgtac tagcataagg acaaaaacct ttatttggtt
    25201 gatgtgctga atgtcctcca caataataac gtgttaactc tgatttattt ttattatgat
    25261 gacctcctga tgaattatgc cctcctgagt gagcatatga aaaattccct acactaatca
    25321 tagctaaact caatactaca gctactaacc ttttcttaac cataatctat tccccccaaa
    25381 atgttatata tttttattat atcatctact atattatatt taaattctta atatacaaaa
    25441 tattactcga ttctgctaat aaacatattt aaacaacata aaaaacctcc taatatttga
    25501 ttaaaaattt acacactcat gcatagcatg tatcaaatat taaaaggttt tatactaata
    25561 attatttatc ttttccatac attttagcta attggtcttg tatctcttta ctttctaaat
    25621 actcatcaaa gtccattttt ctatccatta ttccatttgg agttatctct ataattctat
    25681 ttgctatagt agatataaat tcatggtcat gagaagtaaa taaaagcact cctgggaact
    25741 tttcaagtcc tttatttaca gaagttatac tttctaggtc taagtggtta gtagggtcat
    25801 ctaatacaag tacatttgca tttgaaagca ttagcttact aagcatacat ctaacctttt
    25861 ctcctccaga tataacttga gcttctttta atgcttcttc acctgagaat aacattctac
    25921 ctaaaaatcc tcttataaaa ctttcacttt tttcttcaga gaactgtcta agccagtcaa
    25981 ccaaagaata ttctactccg tcaaaaaact tattatgatt ttttggaaga taatcttgag
    26041 aagtagttac tccccattta tactctccac tgtctggttc aagttctccc ataactatgt
    26101 tgaaaagtgc agtagtagct atttcatctc ccataaatac tactttatca tctctatcca
    26161 atctaaatga cacattatca agaaccttaa ccccatctat agttttagtt aaattgtgta
    26221 cttctaaaac ttcattccca atttctcttg caggtgtaaa tcctacatat ggatatcttc
    26281 ttcttgatgg ttgtatatct tcaacttcta atttctctaa ctgtttcttt cttgatgttg
    26341 cttgtttagc ctttgaagca ttagaactaa atctagctat aaattccttt aattgagcta
    26401 tcttttcttc agtcttttta ttttggtcct tagccagttg taaagccaat tgacttgact
    26461 cataccagaa atcatagttt ccaacgtaca tttgtatttt accaaaatct acgtcaacta
    26521 tattagtaca tatttgattt aggaaatgtc tatcatgtga tactattata actatagact
    26581 cttctaaatc cattataaaa ttatttaacc agtttattga tttaaaatct aagtggtttg
    26641 taggttcgtc cattaatagt atttcaggct taccaaaaag tgattgtgct aacaatacct
    26701 taaccttttc cccaccaact agttccttca tttgtttgta atgcatatct ttcgttatgc
    26761 caagacccat aagtattttc tcagcattag tttctgcatc ccatccgtca agctctgcaa
    26821 actcaccttc aagttcggca gcttttatcc catcttcttc attaaagtct tccttcatat
    26881 acaatgcatc tttttctttc attatgttcc aaagtctctc atgacctctt ataacaacat
    26941 ttaaaacagt ttcttcttca tattcaaagt ggtcctgttt taaaactgac attctttctt
    27001 tatcagttat agatatacta cctgtattag gctctatttc tcctgataat atttttaaaa
    27061 aagtagattt tcccgcacca ttagctccta ttattccata gcaattacct ttagtgaatt
    27121 ttaagttaac atctttaaat agttccttat caccaaatct aagtccaaca cctgtaactt
    27181 gtaacattaa tatattttcc tttctttttg ctcataattt attttatcat aaaactttga
    27241 taacattttt attatatatt atcacgtaaa tagtatattt tttatactaa atttgtgaaa
    27301 tatttattaa aataatacta aaaattgtaa atttataaaa attaacaatc tcttatatta
    27361 tacttataaa gaaatcaaat tgcaacttta ttcattcttt tacacattga aaataagtta
    27421 ttataatttc taaataaata tgcttttctt aaaacatcat tctagctgtt ttgtttcata
    27481 tttaaaaaga gtacttaatt tgtaaatact cttttttaat aactttatat tttagcaaaa
    27541 ttacatgcag gataagtaca tacatcacag ttcatacaaa ggccaccatg accatatcta
    27601 gctatatcat acttatcaag cttttcatca attaaaaccc tagataaaac tatatcaaat
    27661 actgtagttt tatgatacat tgcgcatcct ggtataccca taattggaac ttctccataa
    27721 taagcaagta aaaacatagc tcctggtaat attggtgaac catatgtcac taaatcagct
    27781 ccagtttctt ttatagctgt tggcgtaaca tcatctgggt ctacactcat cccgccagta
    27841 caacagataa gttctgctcc ttgacttata aattctttta ttgcactctt tataatttct
    27901 ttatcatctg ggcatatagt ctgtcctata acttcacaac caaagccttt tactttttct
    27961 tctattactg gtccaaattt atcaacaatt ctgctataaa acacttcatt tcctgtagta
    28021 acaattccta ctttcttagg tttaaaaggt actacattta ctatttttct attaccaact
    28081 actttttttg catcttctaa ttttttctca tctataacca aaggtatcac tcttgttcca
    28141 gctactttta aacctttatt tactataaaa ttattatgaa gagtagccat cattatttct
    28201 ccaacacaat tcaaatcaaa aagtgcatca acatctatct ttaatagacc atcacatgct
    28261 gctataaaat ctatttttcc ttcttttatt tcactaaaat ctaaattttc tccagcagtt
    28321 agttctttta aaaacaatgc gccttcattt tcatgaacca ttccttctga cttttcccat
    28381 acatacaaat tatctttacc aagagataat aacactggaa tatcttcttc ttttactatg
    28441 tgaccctttt taaattttct tcctttaaat tctccaggta ttatttgagt tatgtcgtga
    28501 cataaaactt gtccaacagc atctatagtt tttattagct tcataattta cccccgattc
    28561 tctcatagtc catttttgta tcgatatcaa ataacatttc tttaggaact tctacatact
    28621 ttatttttga tgaatttttt aaaatggttt tacctttttc atcttcttta agtgccaaca
    28681 attcttcttt cttactatat gggaatatga ctggatttcc acacatatct ttgtatcttg
    28741 gaattactat aaaatctcta tctaatttaa aagtatttat aattttatct atatataagt
    28801 tatcaataaa tggctggtct cctacaaaga acatataacc atcacatttt gagctattta
    28861 aaactcctaa ttttatagat tcactttgac ctatatttgc atttttatta tctatatatt
    28921 caaaaccata tttattacac aataacaaaa cctcttcata ttgacttact actacaactt
    28981 gatgaaaatc aatcttgcta acttctctaa atacatgttc tattatagaa cagcctttat
    29041 aatttaataa aagtttattt gctcccattc ttctggcaaa gcctgatgcc attatcactg
    29101 catttatcat atatatcatc cttggtattt ataatatatt gatagttcta tgatttttat
    29161 aatatctcta ttgatattat ctatatatat aatatcatat aaa
//
LOCUS       DAMJWO010000052        28435 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.053, whole genome shotgun sequence.
ACCESSION   DAMJWO010000052 DAMJWO010000000
VERSION     DAMJWO010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28435
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.053"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            584..1957
                     /locus_tag="PC366_002335"
     CDS             584..1957
                     /locus_tag="PC366_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2577844.1"
                     /translation="MNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMNRHDILANSF
                     FDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGKEITAINTTIPIDIKGEFVGAL
                     EISKNMTTIENLLNRNYKKNLVNKVSSRQKKGYEFDDILGESNLIKEAIEKSKKACKS
                     DASVFIYGETGTGKELFSQSIHYGSNRRNYPFIAQNCAALPESLFEGILFGTSKGGFT
                     GAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTKDIPIDVRII
                     ATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDILLLCKKFISKYNKKLNK
                     KVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINLNDYYNLKEN
                     KESNNYSLNDLEGKTLSKIISEIEEKYIYESLEKASYNITKAASILGMNRQNLQYKIK
                     KYNIKIL"
     gene            2213..3280
                     /locus_tag="PC366_002336"
     CDS             2213..3280
                     /locus_tag="PC366_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-binding protein"
                     /protein_id="HDF2577845.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     DVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKIIFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMEEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGDVLIEMEHPQQIIPEVE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            3377..3685
                     /locus_tag="PC366_002337"
     CDS             3377..3685
                     /locus_tag="PC366_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-ketopentanoate thiolase"
                     /protein_id="HDF2577846.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKVNPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            3678..5108
                     /locus_tag="PC366_002338"
     CDS             3678..5108
                     /locus_tag="PC366_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent lyase/thiolase"
                     /protein_id="HDF2577847.1"
                     /translation="MNNSTSIKDMSYQAVMGRNNEIMKNAIGLDYSSFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGAKIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKVIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            5186..5560
                     /locus_tag="PC366_002339"
     CDS             5186..5560
                     /locus_tag="PC366_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HDF2577848.1"
                     /translation="MKKREDDFEVRRKHLQELSDDELKERFWNLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            5554..7758
                     /locus_tag="PC366_002340"
     CDS             5554..7758
                     /locus_tag="PC366_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HDF2577849.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKSNICLSTVPPTAPPAPCLRIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIVMITMMLPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            7758..9167
                     /locus_tag="PC366_002341"
     CDS             7758..9167
                     /locus_tag="PC366_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate mutase L"
                     /protein_id="HDF2577850.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIEYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELYIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            9152..10216
                     /locus_tag="PC366_002342"
     CDS             9152..10216
                     /locus_tag="PC366_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HDF2577851.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERSIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKKLQDINLPKILIRIPMLSELEEVINYCDISFNSELETI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFNNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            10246..11667
                     /gene="nhaC"
                     /locus_tag="PC366_002343"
     CDS             10246..11667
                     /gene="nhaC"
                     /locus_tag="PC366_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDF2577852.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDV"
     gene            12096..12560
                     /locus_tag="PC366_002344"
     CDS             12096..12560
                     /locus_tag="PC366_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDF2577853.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVEFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLAKLDVEVGFPVATYIDGKNEILQRIVPAQKIITAIDL
                     GPYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            12858..13220
                     /locus_tag="PC366_002345"
     CDS             12858..13220
                     /locus_tag="PC366_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2577854.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQD"
     gene            13815..14675
                     /locus_tag="PC366_002346"
     CDS             13815..14675
                     /locus_tag="PC366_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2577855.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIIANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLASMSDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     CVEERDNRQN"
     gene            14933..17047
                     /locus_tag="PC366_002347"
     CDS             14933..17047
                     /locus_tag="PC366_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2577856.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEHDVELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMAEKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHIVIDEMQDYTPIQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REEYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYVGTLTQLISM"
     gene            complement(17309..19552)
                     /locus_tag="PC366_002348"
     CDS             complement(17309..19552)
                     /locus_tag="PC366_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2577857.1"
                     /translation="MSNIIIKGLTQNNLKNISFKIPKNKIVVFTGVSGSGKSSIVFDT
                     IAAESQRQMNETYSSFIRNRLPKYRKPQVELIDNLTASVIVDQTPLGGNARSTVGTIS
                     DLYSSLRLLFSRIGEPYIGTTSYFSFNDPNGMCKNCSGIGRVKVINIESIINPENSWN
                     TGCINDSLFKPNSWYWKQYAESGLFDLDKPIKDYSFEEYNLLLYGSKNKDGKQENPKI
                     EGIFNKYNQTYLNRDISNMSKHTKEKSERLITDKECPVCHGKRLNKETLNCNILGYSI
                     ADMCNMELTDLYDLLLQIKDKRTETVIKTLTDGLKRMIDIGLPYLHLNRESSSLSGGE
                     AQRLKLVRYMGSSLTGMTYIFDEPSAGMHPRDVHRMNQLLKKLRDRGNTVLVVEHDKD
                     VISIADEVIDIGPSAGTQGGHVVFQGSYDKLLLANTLTSNAMNLSLPIKTDSRHPKGT
                     LPIRDACINNLKHIDVDLPVGIMTVVTGVAGSGKSTLISRVFAQKYEKDVIKIDQSPV
                     TATNRSMPATFLGFFDEIRKVFAKENNVEEGLFSFNSKGACPVCDGKGVLVTELVFMD
                     PIINTCEACKGTRYSEEVLSKLYKGKCIVDVLSMTVDESLEFFTEKKLCKILQTMKDV
                     GLPYMTLGQPLSTLSGGERQRIKLAKNLNKKGTIYILDEPTTGLHGSDIEKLMLIFEH
                     IVDKGNTVIIIEHNLDVLKQADWVIDIGPDGGKNGGQVVFEGTPLEMFERGCTITSDF
                     LRKSINI"
     gene            19884..20600
                     /locus_tag="PC366_002349"
     CDS             19884..20600
                     /locus_tag="PC366_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577858.1"
                     /translation="MILIVILSIFIIASINIIILGKENIRDIVIPLTLFIVSDFLFLC
                     GNIICRGGVMLLFIGLFAIPLMLIAFIWICVHMIKLYYKKDLNKRKMIGCIFSIFISI
                     GTIFIPSPSESFRFKLYEKDYSVVAKAILKVYDEKKLSSESVFYIQSDKNELEKIFSK
                     EVIKKMKKLNRNLDVVKISGNRNLVYFFFGAELQSIDGIVIFKDLKHVKPKLDFINRS
                     IQAPRLEYITNNVYYFKGEL"
     gene            20628..21566
                     /gene="blaCDD"
                     /locus_tag="PC366_002350"
     CDS             20628..21566
                     /gene="blaCDD"
                     /locus_tag="PC366_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HDF2577859.1"
                     /translation="MKRKNNFIWIVILLVVVAMGVYYVGRKHNNTKQKHDKNHINSEL
                     NKSKVENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETRRSPCS
                     TFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYYKKLID
                     KVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQTMAKI
                     FEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGMLEREGD
                     TYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            21910..22593
                     /locus_tag="PC366_002351"
     CDS             21910..22593
                     /locus_tag="PC366_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577860.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            22590..25250
                     /locus_tag="PC366_002352"
     CDS             22590..25250
                     /locus_tag="PC366_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577861.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAQKSKGESFKKISETTLTIVGKVDVSTSSVIPAYTALGYLDRTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKMS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYINSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKTVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNTRSRRQEFAMLRSVGLSPE
                     GIKKMLVLEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(25431..26612)
                     /locus_tag="PC366_002353"
     CDS             complement(25431..26612)
                     /locus_tag="PC366_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2577862.1"
                     /translation="MKTPRNINSTVVFIIFCLIITFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(26612..27274)
                     /locus_tag="PC366_002354"
     CDS             complement(26612..27274)
                     /locus_tag="PC366_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2577863.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCGNISLNKVEVKAYLDNVEVLLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            complement(27419..27961)
                     /locus_tag="PC366_002355"
                     /pseudo
     CDS             complement(27419..27961)
                     /locus_tag="PC366_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
     gene            complement(28079..28435)
                     /locus_tag="PC366_002356"
                     /pseudo
     CDS             complement(28079..28435)
                     /locus_tag="PC366_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT        10850 a         3414 c         4865 g         9306 t
ORIGIN      
        1 ataatttata atgtatacaa tttattataa aaaatttaat tttaattttc tatttttgat
       61 actataatat ataatcttga taatttaatt aaaaatctag attttacata ccaaactggt
      121 ttcttatttc gctatcttta cttatgaact catatattcc tataaaggtt attttagaaa
      181 aagttggtta tttaaacatt aataccacaa tttctataga ttgtttgttg aataatctat
      241 aattatatta tggactaaaa aatccaatga gttaatttat tgttttttta tatttgagag
      301 attacaactt attagtttgt atatctcttt ttttaataaa atcaataata tataaaacta
      361 ttggcatatt taatgacaat tcaaatattg tatataacca taatgaaaga tatataaata
      421 aaattttaaa tatacttaaa aatatattaa tataatgtac ataaaaaata tcataaatat
      481 atgataagat aaatacaata gcaatatttt attaattttt tgggttttta tatatttagg
      541 tactggggtg atatagttga accaagagat attttttaaa ataatgaatg aaatattgga
      601 aaatattgat gaaggggtac attttgttaa taaagacggg aaaactataa tctacaataa
      661 ttctgtacaa aaaatggaaa aaatgaacag acacgatatt ttagccaatt cattttttga
      721 tatagtcaac aaaatgaaaa taaacaggag tacactatta gaagttttgg aaaaaaggga
      781 agttatcaaa gacaatattc aaaaatatct ggacaaaaat ggaaaagaga taacagcaat
      841 taatactaca ataccaattg atattaaagg cgagtttgta ggggcacttg aaatatcaaa
      901 gaatatgaca acgatagaaa atttactaaa cagaaattat aaaaaaaatt tagtcaataa
      961 agttagtagt agacaaaaaa agggttatga atttgatgat attttagggg aaagtaattt
     1021 gattaaagaa gcaatagaaa aatctaagaa agcttgcaag tctgatgctt cagtatttat
     1081 atacggtgaa actggaacgg gtaaagagtt atttagccag tccattcatt atggaagtaa
     1141 taggagaaac tatccattta tagcacaaaa ttgtgcggct ttgccggaat cactattcga
     1201 aggtatcctt tttggaacta gcaagggagg atttacagga gcaatagata ggccaggctt
     1261 atttgaacaa gctaacaaag ggacattgtt attggatgag ataaattcca tgcctattat
     1321 gttacaggct aaactattaa gggttttaca agaaggttat gtaagaaggg ttggaggaac
     1381 taaggatata cctatagatg taagaattat tgcaacgaca aatgaaagtc caaaggtaat
     1441 tttaaacgag cataaaatgc gaaaagattt atattatagg cttaacataa ttcatataaa
     1501 aattcctcct cttagagata gaaaagagga catacttcta ttgtgcaaaa aatttatttc
     1561 aaagtataat aaaaagttaa ataaaaaagt ggtaggaatt tcagatgaag ctattaaaat
     1621 tttaaaaaat tacgattggc aaggtaacat aagagagcta gaaaacataa tttattgtac
     1681 tatgagtatg atggaagatg aggtacaaat agaaacaagt atgattaatc taaacgacta
     1741 ttacaatctt aaagagaata aagagagtaa caattattct ttaaacgatt tggagggcaa
     1801 aacacttagt aagattatca gtgagataga agaaaagtat atatatgaat cattagaaaa
     1861 ggcatcgtac aatataacta aagctgcatc aattttaggt atgaataggc aaaatttaca
     1921 gtataaaata aaaaaatata atatcaaaat attataaata agcaagataa aaaaacaaaa
     1981 tagaagtaaa ataaaaaagc aaaatatagg agcaaaatta ttataaaaga gcaaaatatt
     2041 ttgctctttt ttttatttct cataagaaat attatttttt atttatgaaa atacataata
     2101 aaataattat agtttcaacg ttccaataaa tatttacttt aattttaaag ttggcacgat
     2161 ttatgcttta actaattatt gagaatatat aaatttttag gagggtgtat atatgagaaa
     2221 agtaagagta ggaatatggg gatttggagc tatgggaata ggtatggcta atatgattct
     2281 aaagaaagaa ggtatagaaa tagtatctgt ttgtagtaga agtacttcag ggaaaagtat
     2341 gtatgatgtt ttaggaattg aaagaggaga aagaccagaa gttattatca ataaaaatta
     2401 tgaagaagtt tttagagaaa aaagtgtaga tgttgttttg ttagcaactg attcatttac
     2461 taaaaaggct tttgataaaa taattttctt attaaataga aaaataaatg ttatatcaac
     2521 agcagaacaa atggcatatc cacaagctga tgatgcagat ttagctaaaa aaatggatga
     2581 agttgcaaag gaaaatggag taagtatact tggaacagga ataaatccag gatttgtatt
     2641 agatttacta gtattggcac tttcaggtac ttgtgaagaa gttactagta taaaagctaa
     2701 gagagtaaat gatttatctc catttggaaa atctgttatg gaggaacaag gtgttggagt
     2761 aacaagggaa gaatttataa aaggtgtaga agataagact atagcaggtc atgtaggttt
     2821 tgtagaatca ataaatatga tagctgatgg attaggttgg aaattagata agatagaaca
     2881 aacaaaagag ccaataatga ctacagtaga tagaaaatct aaatacggag aggcattggc
     2941 tggaaatgtt gctggttgta gacaatgtgg atatggatat gtaaatggag acgttttaat
     3001 tgaaatggag catccacaac agataatacc agaagtagaa ggtattaaaa caggagacta
     3061 tgtatcaata aaaggtatac caaacattga tttacaaata aatcctgaaa tacctggagg
     3121 agtaggtact tatgcaatga tagtaaactc tattccatta ataataaatg ctagaccagg
     3181 tcttaaaact atgttggata taccagtgcc tagagcaata atgggagaca taagaaatca
     3241 gatagaagtt gaattggaag aagaatcaaa ggctaattag taagataaca gttagctaat
     3301 tggtaaaata atgtttaatt taaaataaca gtaaattaat tagtaaggaa tagtcaatta
     3361 ataaggggat gaaaaaatgg atgctaaaat taatgattgg gttattatac acaatatagt
     3421 attgactcca gaagaaagag ctccacaagt tccagaggat actaagaaag tatccttaga
     3481 aatgtgggtt aaaggtttta tacaaagtga tgcttctata ggcgacttag tagaagttaa
     3541 aacaattaca ggtagacttg taaaaggtaa tttacttaaa gtaaatccat attatactca
     3601 tgattatggt aaatgtatac cagagttact ccaaatagga atccaagcta aagaaatatt
     3661 atttggaggt gtatataatg aataattcaa catcaataaa agatatgagt tatcaagctg
     3721 ttatgggaag aaataacgaa ataatgaaaa atgcaatcgg attggattat tcttcttttg
     3781 aacaagaggg aatagggttt gattatgaga aaatgatgag tgaaacagga tatacattac
     3841 aagatattga agcaattcaa tcacagtatg ctgttggaaa tactcctcta atagagctta
     3901 aaaatttgac taaattagct agaaaatgtg ctaaagaagg taaaggagct aaaatatttg
     3961 taaaagatga agcaatgaat gcatctggta gttttaaagc aagaagagca gctactgcag
     4021 tatatcatgc caaacaaatg ggatataaag gtgtaatagc agctaccagt ggtaactatg
     4081 gtgcagctgt agcatcacaa gcggcaatgc agggattaaa atgtataata gttcaagaat
     4141 gttatgattc taatggtgta ggtcaacctg aaattataga aaaagcacga aaatgtgagg
     4201 catatggagc agaagttgtt cagttaactg ttggaccaga gttattttat acgttcttag
     4261 ttttattaga agaaacaggc tattttaacg catcattata ttcaccattt ggaattgcag
     4321 gtgtagaaac tttaggttat gagttagcta tccaatttag agaaaagtat aaaaaagacc
     4381 ctgatatagt tgtttgtaca aatgcaggtg gtggtaatct tactggaact gcaagaggat
     4441 tgataaaagc tggttccatt aatactaaag tagtaggagc aagtgtagat ttaaaaggat
     4501 tacacatggc tagtgataat caatttaata aaaaatcatt tacaacagga catacaggtt
     4561 ttgggatacc atactgtaca tggcctgata ggtcagatgt acctaggtct gcagctagac
     4621 cacttagata tatggataga tatgtattag taaaacaagg agaagttttt tatacaactg
     4681 aattattggc acagctagaa ggtatagaaa gaggtccagc aggaaataca tctttagcag
     4741 cagcattctc tttagctcaa gagttagatg aggataaagt tatagtggta caagaaacag
     4801 aatatacagg cgcaggtaaa catatatgtc cacagcttac ttttgcaaga gaaaatggaa
     4861 tagatataaa atttggaaat ccaagagaag aaattgcagg agtaaactta atattaccag
     4921 aaagaccaga attattgaaa tgtgttgata ttgatatgaa taaaataaga aagtcattta
     4981 taaaaaattg catatctaat aatcacattg ataatattga taagctaagt aatcgagata
     5041 tagaattttt aatggaagaa gtaaaaagtt caagagattt tgttgttgat gtattaaata
     5101 atttatagta attattgttt ttttatttaa tataaaataa aaattcggaa aattctatta
     5161 aatcaatgcg aatggaggaa tgttcatgaa aaaaagagag gatgattttg aagttagaag
     5221 aaaacatctt caagaactga gtgatgatga gttaaaagaa aggttttgga atttagctac
     5281 ccagatagta gaaccaatga tagaacttgg taaaaagaat acaacaccat caatagaaag
     5341 gtctgtcttg ttgagaatgg gattttcttc tcttgaagta aaacctattt tagaaggggt
     5401 tatggaaaga ggtcttatag gtaaaggagc agggcatgta gtttataaat tggctaaatc
     5461 taaaaatata acggttagag aagcaggttt gttattagtt aagggtgaat attgggatga
     5521 agttacatgt ttatttagag aaggggtaga atcatgttaa aggaaaataa aaaattggat
     5581 atagactata tattaaaaga tttggataaa tataaaccaa aacgaagagg ttgggtttgg
     5641 agagaacact tggaaaatct tgaaatggga ccttttaaat ataaagactg tacaaaacct
     5701 ttaaagaaga gtgtagggct accatcatct aagtatttca ataatataga ccctcaacca
     5761 agtccagtta ttactactga aatagcttct ggtagatttg aggatgatat aagaagaatg
     5821 agaatggcag ctcatcatgg agctgaccat ctaatggtta tcagaactgc tggacaatca
     5881 cattttgatg ggcttataga aggaactcca caaggtatag gtggagttcc aataacaaga
     5941 aaacaagtaa gagctcaaag gaaggctctt gattttatag aagaagaagt tggtagacct
     6001 attaattacc attcatatgt aagtggtgtt gctggtcctg aagtagcagt aatgtttgct
     6061 gaggaaggag tcaatggagc acatcaagac ccacaatata atgttctgta taggaatata
     6121 aacatggtaa ggtcttttgt agatgcttgt gaggcaaaga aaataatggc ttttgccaat
     6181 atagctcaaa ttgatggagc acataatgct aatgctactg ctagagaagc atggaaggta
     6241 atgcctgaac ttatggttca acacgcttta aactctatat tctcagaaaa aataggtata
     6301 gataaaagta atatatgctt atcaacagtt ccaccaacag cacctccagc accatgttta
     6361 agaatagact taccttacgc tgttgcactt agagaattat ttagtgatta taagatgaga
     6421 gctcaaatga atactaaata tatggaatca tcaactagag aagcaacagt tactcatgta
     6481 ttaaacttat taacatcagt attaactaga gctgacatac aatcaactat aacacctgat
     6541 gaaggtagaa atgtaccttg gcatatatac aatatagaag catgtgatac agcaaagcaa
     6601 gctttagttg gtatggatgg gcttatggat atgatagaac ttaaagatgt cggtgaatta
     6661 agagacaaag caagagaact taaagaaaga gctgtattat atatggaaga aatatctgaa
     6721 gttggtggat attttgaatc tgtggaacaa ggattttttg ttgattctgg aaattatcca
     6781 gaaagaaatg gtgatggaat atctagaaaa ataaaaggtg gagttggtga aggtactgtt
     6841 tatgaaagag aagaagatta tttagcacct gtaactgctc actttggata caataatgta
     6901 gctcaatatg atgaaaatgc tatagataat ccatcaatgt taatagatgg atgtacattt
     6961 gaaaatccag acaaaataat atatattgat gagcttgacg attttgataa tgtagaaaat
     7021 agactaaaag aatcatatga gtacagaaat ggaactaaaa ttaagcctga aatggaatgg
     7081 tgtgcagatg gaattgtaat gataacaatg atgcttccta ctgataaaag aacagcagag
     7141 tttgcagctt tggaatttgt caaaaaaatg aacttacaag aaattgaggt cataagtaga
     7201 gaagttatgc atgaatctga agggactaga atagaagtga aaggaagagt tccgtttgat
     7261 atagatttaa acaatttagt aataccagaa gaacctaagg tactaactga tgaagaaata
     7321 agagcagata tagaagaaaa acctatgaaa atagtttcag ctacggttgg agaagatgaa
     7381 cattcagttg gtttaagaga aataatagat ataaaacatg gaggtattga aaaatatggc
     7441 atagaatgcc actatctagg gacttctgta cctgtagaaa aattggtaga tgcagcgatt
     7501 gaactgaatg cagatgcaat acttgcatct acaataataa gtcatgatga tattcactat
     7561 aaaaacatga aaaaattaca cgattattgt gtagaaaaag gtataagaga taaagtaatg
     7621 attgcgtgtg gaggaacaca agtaacacct gaaatagctg ttgaacaagg catcgatgct
     7681 ggatttggaa gaaacagcaa aggcatacat gtagccactt tcttagttga aaaaagaaga
     7741 gaaatgagta ataaataatg gaaaatagca aagtttcttt aaaaatagat gtgttggtag
     7801 ctgaaattgg aagtactact acagtggtaa acgctttcca cgatattaat actaacaatc
     7861 ctatattttt gggtcaaggt caagctccaa caacagtgtt tgaaggtggc gatgtaagaa
     7921 atggcttatc aggtgctatt aaagatttag ctaataaatt atctgtagat gatatagagt
     7981 ataatgatat gtttgcaact tctagtgcag ctggtggatt aaaaatgact gttcatggat
     8041 tagtctatga tatgacagta aaagcagcta aagaagcagc tttaggggct ggagctgtta
     8101 ttcgtcaaat aacatcaggt agaattaaaa gaactgattt aaataaaata aaagaaataa
     8161 acccaaacat aattttaata gctggtggag tcgattatgg agaaagagat acagctattt
     8221 ataatgcaga aatgatagct tctatgaatc taggcatacc agttatatat gctggtaatg
     8281 ttgaaaatca agaggaaata aggttaatat ttgaagatac taattataag ctttatataa
     8341 ctgaaaatgt ataccctaaa atagatttat tgaatataga acctacaaga agaatcattc
     8401 aaagtgtatt tgaagaacac ataactacag caccaggaat gaaatacatt aaagaaatgg
     8461 ttaatgaaaa tattactcca accccaggag ctgtaatgga agcttctaaa cttttatata
     8521 aaaatattgg agatttatta actttggatg taggtggagc aactactgat gtacattctg
     8581 ttacagatgg aagtgactat attaataaaa ttttggttaa tcctgaacct actgcaaaga
     8641 gaagtgttga gggggattta ggtgtatatg taaatatgaa gaatatagta gaagttatag
     8701 gtaaagaaaa cttacaaagt gaactatata tagatattga tgcagtaata gagaattatc
     8761 ctccaatacc aaaatcaaaa gaagaaatat tatttgttga gaggttgaca aaagaagctg
     8821 ttgttaaagc tatgctaaga cattcaggaa aaataagaaa tatctatgga acaactggaa
     8881 aagtcaaaat tgcagaaggg aaagatttaa cagaagtaag atatatagtt ggtacagggg
     8941 gagcacttac taggctccct agtagaattg aaatattaga taatatgctc aaatacaata
     9001 aaaataatga attactattt ccaaaggaaa aaacaaagat attaatagat aatgactata
     9061 ttatggcatc tatgggtgtt ttatctaaaa aatatgaaga agcatctctt aagctcctgt
     9121 taaaaagttt gaattttgag gaggaaagat tatgtatcct aggttagaaa tagatataga
     9181 aaagttaaag cataatgcaa aattaatttc gcagatgtgt catgaaagaa gtattaagat
     9241 atcttttgtt actaaatcat tttgtgcaca aaaagaaata gtagaagaaa tatgtagtga
     9301 aggaatagac catatagcag attcaagaat acaaaactta aaaaaattac aagatataaa
     9361 tctacctaag atattgatta gaatcccaat gttaagtgaa ttagaagaag ttatcaatta
     9421 ttgcgatatt agttttaact cagaattaga aacaataaag aaattaaatg aattatgtga
     9481 aagtaaaaat attattcata agatagttct tatgtttgac ttaggcgatt tacgagaagg
     9541 atacttttat gaagaagact tttttaataa tgtaagagag atagtaagat taaaaaatat
     9601 tgaaataatt ggtatagcta caaacttaac ctgttatgga gctattatac catctaggga
     9661 aaatataggc agactggtaa gtatagcaaa aagaatggaa gaaaaatttg gaataaatct
     9721 agaaatagta tctggaggta attcaagttc tattcatctg ttgataaata ataatatgcc
     9781 agaaggtatt actaatttga gaataggcga gtccattcta cttggtagag aaacggcata
     9841 cggtgaaaat ataaatggaa catatcaaga tgcatttaaa ttaatatgcc aagtagttga
     9901 atgtaaagaa aaaccatcag ttcctattgg agaaatagga gttgatgcct ttagaaataa
     9961 acctgtttat gaagataagg gaatcttaaa aagggcaatc atagctatag gtaaacaaga
    10021 tataaatatt gactctttaa ttccaataga cactgatata aaaatattag gggcaagttc
    10081 agaccacatg atactagatg taagtaacac aaaatatgat tataaattag gtgacaattt
    10141 agaattttta ttaacttatg ggggtatcat gtcatctagt acaagcaaat atgtttcaaa
    10201 aaaaattata gtgtagtgtt taaataatta ggaggaaact attttatgaa agagcgagaa
    10261 tgtagaaaag caagtctgtt tgatgcaatg ataccaatta cttgtttgat attattttta
    10321 agtctaggag tattagtgta tggttcatca cctcatgtac cactaatagg agcagcagca
    10381 gtagcaggac ttgtggctgt atatagactt ggatttaaat ggaaagagtt agaattaagt
    10441 atgtttaata gtataaagat ggcaatgcaa gcaatcttaa tcataattat aataggcgta
    10501 cttataggaa cttggatagt aagtggagta gttccatgta tgatttactg gggactaaaa
    10561 attttatcac caaatatttt tttagtagca tcaacattag tctgtgcaat agtatctctt
    10621 gcgacaggtt catcttggag cacaatgggt acagtaggag tagctctttt aggaattggt
    10681 caaagtttag gtatgccaat tggattaatc gtaggttcta taatatctgg agcttacttt
    10741 ggagataaac tatcaccttt atctgaaacg actaacttag ctccagcaat ggcaggaaca
    10801 gatttgttta cacatataaa atatatgtta tattcgacta taccatcatt attaatttgt
    10861 ttagtaattt atggtgtaat tggaatgaag tattcaggtc aagcactaga tataaaacaa
    10921 atagaattaa ttaggtctac attagattct acatttaata ctttatcacc agtattatta
    10981 ttagctccag caatagtaat tggattagtt gtatttaaag ttcctgctat accagggctt
    11041 atagtaggtg ctgtattggg agtattgttt gcagtagttt ttcaaggaga atctatgaat
    11101 acgatattag atgcagcaca aaatggatat gtttcgtcaa cacaaataca ggaggtagat
    11161 gctttattat ctaaaggtgg gattatgaat atgatgtcca ctgtatcctt aacaatatgc
    11221 gctttatctc ttggaggtat tttagaaaaa acaggtatgc ttgaagtagt agcatcttct
    11281 ttactaagat tagcaaaggg tgtatttgga acagtattat gtactatggt aacttgtaca
    11341 attaccaata taatagcagg tgaacaatat ctatctatag ttataccagg aagaatgtat
    11401 aataaggaat ataaaaagag aggtatacat cctaagatgt tgtcgagagc tttagaagat
    11461 agcggaactt taacttctcc attagtacca tggaatacat gcggggcgta tataacagca
    11521 acattaggtg tatctgcact aacatatggt ccatacgctt tattaaatat tataaatcca
    11581 atagtatctt tagtattaat tgcatgtaag tttaaaatag caagaataga agatgaacct
    11641 gaaacttgtt taaattttga tgtttgataa tagataactt atgtaagaac gtaggaacta
    11701 gggggggagc ctgtggggaa ttagtaagac atattttagt gtgcgaaatt ctataaatca
    11761 gtaatcttgt gactttagcc atgggaggtt cagattagta aatttatagt tttatattag
    11821 tctatacttt gatcttttaa ttgtttgtat aaatttttta tagaaaaaga tttcttttag
    11881 acttgcctaa aaattaggca agtcttttaa gtatgttctg attataagag cactgtgtga
    11941 caagaatgat gagattattt ttgctatact ttcgatataa gaaatggaag gaggttatgt
    12001 tttatattta tatgaaataa ttagttacac agtgaatttt cgtataattt ggtataaaaa
    12061 gattagaaat gaaaataaag taatggagga ataaaatgac tagaatatcc aatataacaa
    12121 tagctgaaca atctgagtac tgttttttgg caatacgaaa aacaattgac tttatggtag
    12181 agttttcaga gttttcaaaa caaagttttg aaaaaatttc taaatatctg gaggagagag
    12241 gaattttatc ttcaggagca ccgattgtat gttttcataa catggattta gcaaaattgg
    12301 atgttgaagt agggtttcct gtagccactt atatagatgg gaaaaatgag attctacaaa
    12361 ggattgttcc tgcacagaaa ataataactg caattgattt aggaccttat gaattacaag
    12421 accctacttt agaagactta ttttcatggg caaatagcaa tggatataaa cttcatggcg
    12481 atatatatta ccagtattta aatgatatca atcgtccagc tagtgaatat cttacgaaaa
    12541 tgatgttacc cattatatag aaagttaaag attatcgttt gttagttgat aattagaaga
    12601 acatttaatg ctactgcata aattttatcc taaataatat caaggtgatt taatttatgt
    12661 attctaatgt aactgtagat aatcaattta taactaactt agtgtaattt agatttaatt
    12721 tattattcta atgtaacccc aatatattgt taaggtctac ttaagatgct caaaaggcta
    12781 tgcttaattt attgttatat aatttgtaga gtggtataat ttagaagtga tactatatag
    12841 atatataggg ggaaaatatg aaaatatatg atatattaac acgtttttat attcaagata
    12901 tagaaaaagc catacctttt tatgagaatc ttttaaaaga aaaatgttct ttgcgttttt
    12961 cttataaaga agttgggttg gaattagcgc aaataggaaa tgttttacta ttatctggtt
    13021 ctgatgatgc tcttaaacca tttatagaaa caaaatctac ttttatggtt gattctgttg
    13081 atgaatggag aagttatcta ttggataatg gagcagttgt agtaagagat aagaaaaaag
    13141 ttcctacagg atataatatg acattgagac atccagatgg tacaattata gaatatgttc
    13201 aacatacaaa gcaggattag ttaaaaatag attttactac tgagcaacta attagaatct
    13261 attcttagac gtacaattta ttatttttgg tattaataga ttataagtca aattataata
    13321 tttcaaaata gaatagaaat ttatttacat aaaagagagt gtttaaaaat gaacttttta
    13381 gttcacgaag cactcctttt tgtatgaaat caaatacatc aatatataaa acaaactgat
    13441 gaagagctta aattaaaata aaaagattca taacaggacc ccattaaact ttaagatagg
    13501 gtaagtttgt aatcatatta aataattgta aaaagctgtt tttagtcgta taatataaat
    13561 atttatcatt taattaagga atctaaaagg aatctaataa gaagaaaata ataaataact
    13621 ttttagattt actaaatgaa aaattattga aaattaaagg attagagtct ttaatcagaa
    13681 agtaaaaagt aatatattaa atttatgaat tgaaaactta aacaacaaat ttgtttataa
    13741 aatagcaaga ttcattaaat ataactaagt aataattgat ataatgttgc atggataaaa
    13801 ggagggaagc tgcaatgtct tacaaagtaa ttaatgtcat aactgctatt gactatatag
    13861 aggagcattt atcagaaaag ctggatttag atataattgc taatgctgtt cattactcaa
    13921 aatatcacct gcatagaact ttcacaactt ctgttggtct aacaatgcat gattacataa
    13981 agcggagaaa gttgacagaa gcagcaaaat tattggtatt ttcaaagaaa ccaattattg
    14041 aaattgcatt gatagctgga tatgaaagtc aacaggcatt cacttctata tttaaagcta
    14101 tgtataaaaa atctccaaat aaatatagga aagaacaaga attttatcct ttgcagctaa
    14161 gatttgtttt gaaaaaagat aacctatttt caaagaatgt actagagttg gaaaaagaaa
    14221 ttaaacttgc aagtatgtct gacataccat tatggatgaa tttagtgaga ttagtcatag
    14281 atggatttcc aaatttgcaa gaggaagaat atatatatca attagaacag tatattttag
    14341 aagaaagagc tttaatatta aaacttaata atgtcgctat tgcaaatatg gtgtttaata
    14401 gagaaactag aagtattgat ttttttggaa tacatccaca gtatcgtaat tcagacattg
    14461 cacaagtgtt tttgaagaaa gttattgaag atttcttgat agatacagat atctcaatta
    14521 ctacctttcg agagggtgac aaagctgata caggacatag agatatgata aagaagttgg
    14581 ggtttgcaga agcagagttg cttgtggaat ttggatatcc tactcaaaaa tttattcttc
    14641 cttgtgtaga agaaagagat aatagacaaa attaattgta gattaaatgc aaagtttacc
    14701 acatattttt tgtttgaatt attttatata taagagtatt tctgctttta atgtattttg
    14761 cttgtaagtg tacttatggt aataaatata gaaagattta gttttttaaa aaaagaactt
    14821 taaagctaaa aagctaacat ttaagttaaa tagcaagaat gattaaaaac tccaaaacac
    14881 aattaagtat aatgattcag tgtaagtact taattaacaa aggaggattt aaatgtctga
    14941 aaataaacaa gtagtaaatt gcgatattat tgcatccaat tctaaacata atatgtgtga
    15001 acatgatgta gagttattaa ctttttttcc agatgagatt gcacatctaa tagagataaa
    15061 taacaagcta gacaatgctt ttaagaaagc tgaaaatctt gttgacaagc ttgataagga
    15121 ttatatggac gctaaaatgt atatggtaaa aaatcgtggt gaaatagacc cacatgaaat
    15181 gtttcaaaat gaacaaggac taaaacaaat agataactat ggggctttta tggtaaaagt
    15241 tcgagataag attaataaaa tcaaagattc tccatacttt gctagaatag attttaggct
    15301 gaaagatatg gatgatgaat ctaagtatta tattggtaga tttgcatttg attatgaaga
    15361 tgagcttata atacttgact ggcgttctcc aattgccagt atgttttatg attatgaaat
    15421 cggaaaagct ggatatgatg ctccaatagg atgggtggat ggagaaataa caagaaaacg
    15481 acaatttaaa attaaaaatg gaaaattgga atatgcacta gaaagttcca ttaatataca
    15541 agatgatatt cttcaaaaag aacttagtca cacttcagat gaaaaaatga agtcaatcat
    15601 ttcaacaata caaaaggaac aaaatcaaat tattagaaat gataaagctg atacactgat
    15661 tattcaaggg gtagctggtt ctgggaaaac atctatagca ttacacagaa ttgcttttct
    15721 tctttatcga tttaaagata aaatatcagc aaataatgta attatcctat cacctaataa
    15781 agtctttgga gactatattt ccaatgtcct tcctgagctt ggagaagaac cattatgtga
    15841 attaagtttt gaaaatatag cagaggtaca attagataga gttattaatt ttgaaagtga
    15901 gaaagaccca ttagaaataa atgatgctaa atggtctgaa agagtgcgtt ttaaatctac
    15961 acttgatttt gtaaaactta ttgatgatta tataaaacaa atgccaaata agatttttat
    16021 tccaaaagac tacacttttg gaagttttac agctaaaagt gactggatac agagtagatt
    16081 tgaggcatat aacagatatc cagttaagaa gagattagaa aaggtagctg aagacattca
    16141 ttataaattt gaatcagata atattatgga agaagattta ccaaaggtaa aaagtatact
    16201 taaaagtttg aatggaatgt tgacaataaa aaatactctt acactatata aggatttctt
    16261 taaacaaatg aatatatcaa acatgtttgt gatggcagaa aagaaaacac ttgaatggtc
    16321 agatgtatac ccatttatat atattcatgc tgcatatgaa ggtatacaag aagataagat
    16381 tataaggcat attgttattg atgaaatgca ggactataca cctattcaat atgctgtaat
    16441 aaacttactt tttaagtgta aaaagactat tcttggagat tttggacaat tggttaatcc
    16501 taatcatact catacattag atgatatgaa acagctatat aatgatgggg aactagttat
    16561 gttgaacaag agttaccgtt ctacttttga gattattaat ttcgccaaaa agattcaaga
    16621 tatatcttca ttagagccta ttgaacgaca tggtgaagaa ccggctttat taaaatgtaa
    16681 taacgagcaa gatgaaataa ataagataaa aatagaaatt gaagaattta aaaagagtga
    16741 taatgcgact cttggtatta tattaaagac agataatgac gctaaagctg tatatgatgc
    16801 gttaagagaa gaatatagtg ttcacttaat atcttctgaa agttctagct ttacaaaagg
    16861 agtatccata acttctatta aaatgtcaaa aggtttagag tttgatgaag ttattgtacc
    16921 ttcagtaaat aataaaacat attatagtga ttatgaccgc agtttgttat atattgcttg
    16981 tacacgagct atgcacaaac ttaagttaac atatgttggt acattaactc aacttataag
    17041 catgtagatt atatcttata tgcatttatt atcgtaaata taaattggga caaagattca
    17101 tcaataaatc aacaaaaaat aatacttata aatttataaa aaatgaaagc tataaattac
    17161 atttgaaatt ttataaaatt ttgtgattta tagcttttat aatattaatt tcttttaaaa
    17221 taaagttaaa ctttaaattt atgaaataaa acaaagtagt aatatatatg taatagttct
    17281 taatttttta atattagtat tatattatct atatatttat tgattttcta aggaaatctg
    17341 atgttatagt gcaacctctt tcaaacattt ctagtggtgt accttcaaat acgacctgac
    17401 caccgttttt gccaccatca ggaccaatat caattaccca gtctgcttgt ttcaatacat
    17461 ccaaattatg ttcaattata attacagtat tacctttatc aactatatgc tcaaaaatca
    17521 acataagctt ttcaatatca gaaccatgaa gccctgtagt tggctcatct aaaatatata
    17581 tagtaccttt tttgttgagg tttttagcta acttaattcg ttgacgttct cctccagata
    17641 gtgtgctaag tggttgacct aaggtcatat aaggtaaacc aacatctttc attgtttgta
    17701 agattttaca tagcttcttt tctgtaaaaa attcaagaga ttcatctact gtcatagata
    17761 gtacatcaac tatacattta cctttatata attttgacaa aacttcttca ctatatctag
    17821 tacctttgca agcttcacat gtattaataa tagggtccat gaatacaagc tctgtaacaa
    17881 gtactccttt accatcacaa acaggacaag ctccctttga attaaagctg aataaacctt
    17941 cttcaacatt attttcttta gcaaatactt ttcttatctc atcaaagaaa ccaagaaatg
    18001 tagcaggcat agaacgattt gtagctgtaa ctgggctttg gtcgatttta ataacatctt
    18061 tttcgtattt ttgtgcaaaa acacgagaga ttaaagtact cttgccagaa cctgctactc
    18121 cagtaacgac agtcataatt ccaactggta aatctacatc aatatgtttt agattattta
    18181 tgcaagcatc tctaattgga agggtacctt ttggatgacg agagtcagtt tttataggta
    18241 atgatagatt cattgcattt gaagtaagag tgtttgctaa aagtaattta tcataagagc
    18301 cttggaatac aacatgtcca ccctgagtac cagcacttgg gccaatatct ataacttcat
    18361 ctgctatgga gataacatct ttatcatgct ctactacaag gacagtattt cctctatctc
    18421 taagtttttt taatagctga ttcatacgat gtacatctcg tggatgcata ccagcactag
    18481 gttcatcgaa aatataagtc atacctgtga gactgctccc catatagcgt acaagtttta
    18541 atctttgagc ttctcctcca gatagagatg atgattctct atttagatgt aggtaaggga
    18601 gaccaatatc aatcattctt tttaaaccat cagtaagagt ctttattaca gtttcagttc
    18661 ttttatcttt tatttgtaac aataaatcat aaaggtcagt aagttccata ttgcacatat
    18721 ctgcaatcga atatcctaaa atattacagt taagagtttc tttatttaat ctttttccat
    18781 gacatacagg acattcctta tctgttataa gtctttctga tttttctttt gtgtgtttgc
    18841 tcatattgct aatatctcga tttagatatg tttgattgta tttgttaaaa ataccctcta
    18901 tttttggatt ttcttgtttt ccatctttat tttttgaacc ataaagcaat aaattatatt
    18961 cttcaaaaga ataatctttt ataggtttat ctaaatcaaa aagtccagac tctgcatact
    19021 gcttccagta ccatgaatta ggtttaaata aagagtcatt tatacatcct gtattccatg
    19081 aattttcagg atttataata gattcaatat tgattacttt aactctacca atcccagaac
    19141 aatttttaca cataccattt gggtcattaa aagaaaaata tgaagttgtt cctatgtagg
    19201 gttctccaat tctagaaaat aataatctta atgatgaata caaatcactt atagtgccaa
    19261 ctgtagaacg tgcattgcca ccaagaggag tttggtctac gattacagaa gcagttaaat
    19321 tatcaatcag ctccacctga ggttttctat atttaggtag cctatttctg ataaatgaag
    19381 aatatgtttc attcatctgc ctttgtgatt ctgctgcaat tgtatcaaat acgatactgg
    19441 attttccaga accagaaact ccagtaaaaa caacaatttt atttttagga attttaaatg
    19501 atatattttt taggttattt tgtgtaagtc cttttattat aatatttgac atgaatgtta
    19561 aatcctttct gagtacattt tagtaaagca attatattat gtaaccatat tataataaaa
    19621 ttaaaatcta ctttcttgat atattctgct atgttataga aggtatttct aaatttaacc
    19681 aatcccatac aatctgaata aatgatagtt gataatagat aaaaaagtat ataatagata
    19741 ctcgtaattt gataagtaca aagataatta tacaattaaa acgacttgac atttaaaact
    19801 tactattgta atatttaaat attacaatag taagttttaa atagagaata aataattacc
    19861 tcacaaactg aaaggaggac ataatgatac taatagttat attgagtata ttcatcatag
    19921 cctcaatcaa cataattata ttaggtaaag aaaatataag agatatagtt atccctttaa
    19981 ctctatttat tgtaagtgat tttttatttt tgtgtggaaa tataatatgt aggggaggag
    20041 taatgctact atttataggt ttatttgcaa taccattgat gctaattgca tttatatgga
    20101 tttgtgtaca tatgattaag ctttactata aaaaagattt aaataaaaga aaaatgattg
    20161 gatgtatatt tagtatcttt ataagtatag gtactatatt tattcctagt ccaagtgaaa
    20221 gttttagatt taaactttat gaaaaagatt atagtgtagt agctaaagct attttgaaag
    20281 tttatgatga aaaaaagtta agctctgaat ctgtctttta tattcaatct gataaaaatg
    20341 aattggagaa gatattttct aaagaagtaa taaaaaaaat gaaaaaacta aacagaaatt
    20401 tagatgtagt taaaatttct gggaatagaa atttagtcta ttttttcttt ggagctgaat
    20461 tacaatctat tgatggtatt gtgattttta aagatttaaa acatgttaaa ccaaagttag
    20521 attttataaa tagaagtatt caagctccta gattggagta tattacaaat aatgtatatt
    20581 attttaaagg tgaactataa acttatgtag aggagatggt ataaagtatg aaaagaaaaa
    20641 ataattttat ttggatagtt attcttctag ttgttgtagc tatgggagta tattatgtag
    20701 gaagaaagca taacaacaca aaacaaaaac atgataagaa tcatataaac tctgaattaa
    20761 ataaatccaa agttgaaaac aatgataaaa acaaaaaaga aaaaattaat atggttgact
    20821 atagtgactg ttttgaaggt attagtggag gagctatttt ttataatact aaaaataaag
    20881 aatataatat atataacaaa gaattaattg aaacaagaag gtcaccatgt tctactttta
    20941 aaatagtttc aactttaatt ggtttagaaa aaggggtaat aaactcaaaa gaatcagtta
    21001 tgggatatga tggtacagag tatccaaata aaaattggaa taaaaatctt agtttagaag
    21061 aggcatttaa ggagtcttgt gtttggtact acaaaaaatt gatagataaa gttgatgcta
    21121 aatctgtcca aaacatttta gatgatttaa agtatgggaa ttgcgatatt agcgaatggg
    21181 aaggagattt aaaaaatgga aagggacatt taaatggatt ttggttagaa tcttcattac
    21241 aaatatctcc aaaagaacaa gtgcaaacaa tggcaaaaat atttgaggga gatacaaact
    21301 ttaaaaaaga gcatattaat attttaagag atattatgaa aatagatgta aatgataaaa
    21361 acataaatgt atatggaaaa actggaacag gatttgatga aaaaaataaa cgtgtggatg
    21421 catggtttgt tggtatgcta gagcgtgaag gtgacaccta ttattttgct attaaatcag
    21481 atgattccaa taaagaaatt acagggccaa aggtaaagga aattgcaatt aatataatta
    21541 agaaatatta tagtgtaagg gaataaactt aattttattt gtaaatatta tttacctata
    21601 gtctgtaata tttattaaat aattttacta aattgagtct atatagagca aaactccttt
    21661 agtacataaa atacttgcta ttgattatta aattgaatac ctatagattt aaagttaata
    21721 ccttttaaag actatgtaat atattaaaag tataaataaa atatattgca tagtttttgt
    21781 tttatattat aattttaaat aatgtgcaaa aactaaacaa tatttttaat agtaatttat
    21841 atttgtattc atgtcactat aatgtcattt taggttgcta aaatttaacc ataaaggaga
    21901 tgattgtata tggaaatatt aaaatgtgaa aatctcacaa aaatatatgg ttcaaatcaa
    21961 accagagtga cagcccttaa taatgtaaat ttatcagttc aaaaaggtga ttttgtatcc
    22021 attgtaggag catctggttc tggcaaatct acattgttac atctgcttgg gggagtagat
    22081 agacctacat ctggaaagat ttatgttgaa gatacagaaa tatcaagttt aaaggaagaa
    22141 gctcttgcag tttttagacg tagaaaagta ggtcttattt atcaatttta taatcttata
    22201 cctacccttg atgttagaaa aaatatatta ttacccatgt tacttgataa aagaaaggtg
    22261 gatgaggata gattctctga gattgtatct atattgggat tatctgatag attaaaccat
    22321 cttccaagtc aactttcagg tggacaacaa caaagggtat ctatagctag aagtttaatc
    22381 tatagaccag ctattttatt agcagatgag ccaactggta atcttgatag aaaaaattca
    22441 gaagaaattg tagacttgtt aaacttatca aataaacgat ttaatcagac aatacttctt
    22501 attactcatg atgagaaaat agcactagag gcaaatcgta ttgtaactat ggaagatgga
    22561 gtgattgtct ctgaaaaggt ggtgaagaaa tgaatattct tcaagaatac accttagact
    22621 ttgtacgacg caataaacgt agtagtatag ctataatgtt agctatatta cttactacaa
    22681 ccatgatgtc ttctttgtgt ggactgttgt ataccatgtg gacagatttt ataagacttt
    22741 caattgagaa agaaggtaac tggcatggtg aattgtttga ctatacttat ggaagtgact
    22801 taccattaat tgaaaatttt tcttcagttg atgatgtaat ggtaaaagga caatggtatg
    22861 taggcaaaat taatgatgag aaaagagatt atataattta tagaaatgct acatcagagt
    22921 attggaattc tatgccagaa aaggatacta taatagaggg tcgtcgacca aataatgcta
    22981 atgaaattgc attatcaaaa caatattttg agaataatcc aagtgtaaaa attggggata
    23041 aaattactct tccaatagga gatagaatcc taaatggaaa gcctcttgaa cccatagctc
    23101 aaaaatcgaa aggggaaagt tttaaaaaaa tttcagagac tacattgaca atagtaggaa
    23161 aggtagatgt ttccacttca tcagtaatac ctgcatatac agctcttgga tatcttgata
    23221 gaacaagtat aaaacctaat gatagtataa ctgtgtactt gcgatttaaa aatataagag
    23281 acacatacaa ggaacttcca aaacttgcta aatcattggg gtggaagact aatgaatatg
    23341 gaaaatacaa tcttaaatat aatagtaatt atcttttaaa aatgttagtc ttttccccag
    23401 aacagaaagc atctatgagc agtatatcaa aattttcaac tcctattatg tatcttacaa
    23461 tagcaatttt tacagtagct gtgtttgtaa tggtgattta caacgcgttt tcactatctg
    23521 caaatgctag acttactcaa ttagggatat tatctagtgt tggtgcatca ccaaaacaga
    23581 ttaaaatgtc tgtagtgttt gaaggttttt tgcttacaat tataccattg ccaataggtt
    23641 tatttttagg atggttattg tgtaataggc ttatagttta tattaattca gttaattatc
    23701 atactgatgt tccagaagtg gtatttactt atggtattcc tgcttttctg ccagcagttt
    23761 tacttacaat agtaacagtc tggatttctg cacttatacc agcacgaaaa gtatcaaaga
    23821 tatctcctat agaagcaata cgacaaggag atagtgttaa aatcaaaaag tcgcataaat
    23881 attcattagg aaagatattt ggaatagaag gagaacttgc atcaaacgca ctacgtgctc
    23941 gtaaaaaatc ttatcgtact gcaacaatat ctttaacatt atctttttta ttacttacat
    24001 gttttttgca tataattgca aatcaagaag gagcaaaagc tgtttatgga agtgataatt
    24061 ataaggacca aagagatata gcagtttatt tggaaaatag tgaacctgta gagtctgctt
    24121 tcattgaaaa attagataat acagaaggtg taaaaagttc actatattat caaaaaatgt
    24181 ctgcttccac ttggctgact gaaaaagatg catcaaaaga acttgcgaaa aatggaggat
    24241 ttaaaagtat agtttcatct aaaaaatact ctcctataga acgtgatggc aagtttcgta
    24301 taatttcaaa tataattggg cttgatgata agagttttac agaatattgt aggcaaattt
    24361 ctgtagaccc aaagttattt tatgatacaa aaaatccaac ctcaattgta tataataagg
    24421 aggaagatat taatcgtagt acacgtagaa ataaagtata tatagattat ttaaatcttt
    24481 caataggaga taacattaaa ttaaatgaaa aagtatatga cgaagataaa ggggattata
    24541 cttacaacat gaaagtggga gctattacaa gcacacttcc taaaacagta gatactagtt
    24601 caaaatatac attaatgcaa atagtgccaa tgtctatggt gcaggaaata tctaaaaatt
    24661 atgatgaagt aagtaggtta cgttcaaata ggctgatagg agtatttaaa gtaaataatc
    24721 gtgaggacat tcctagagta agagaaaaat tagagtccat ttataataaa gactatggtt
    24781 caggagatta tagtattgag gatgttttag aaagtgaaaa acaaaaggct agtggaataa
    24841 agaccatgaa tttaatagta ggctttatta caggtttatt ggctatgatt ggattatcaa
    24901 atgtacttgc tacagtgtca ggaaatacta gaagtagacg acaagagttt gctatgttgc
    24961 gttctgttgg attatctcca gaaggcataa aaaagatgct tgttttggaa ggtttgttct
    25021 taggaattac accattacta cttagtattc ctgtgcaaat aggaatagtg tatgcttttc
    25081 tacgtataaa tgaaatatat tttatagagt atttaccatt tgcacctata tctacaataa
    25141 taggttttac tatattgata ctttttattg taatagcatc atatatgaca ggatacaagc
    25201 agttgaagaa tgaaaatata gtagaatcta taaaaaatga aacaatataa acaaaagcta
    25261 tttgaactta tttaaaggtt tcgatttaag actacttaca agtataggga tagttaattt
    25321 gtttgtttaa taaaacctta aatgtaaata gaagtatatt actaaaacaa tagataacat
    25381 agaatataga tatagctgga ttataggtat tttacctata atccagcatt ttatgtgtaa
    25441 aatttaatta tgaatcttgc accaccatta tggcaatttt ctgcatgtag agtaccattt
    25501 tgacgttcta taatagactt tgatagagca agccctatac caatactgtc cttactagca
    25561 tttttaccac gataaaatct attaaaaata tatggaagtt cttcctgagc aaacccttta
    25621 ccattatctt ctatgataat ctcaacatat agaggatttt gactataata agcaactata
    25681 tatccaccat cttctatatg ctcactacaa tttttaagaa tatttaaaag agcttctaaa
    25741 gtccaattaa tatcgatttc aaattctacc gaaggagaag cctcgatagt aaatgtctga
    25801 tgtttttctc ttaaagaacc ttctataggc tcaattgcat aagtaagaag agaatgtaca
    25861 tctataagtt tgctttcaaa tattaaagta cttgcatcca attttgataa tgtaagtaaa
    25921 gatgaaacta gtctctcaag tcttgagatt tgatttgtaa gtctgttaat ataatctatt
    25981 tcttcatctg gacaattttc tgaaagtaat tgtgccataa gtgacataga agtaattgga
    26041 gtcttaagtt gatgagcaat atctgcaaga ttatctgaaa gagtttgtct ttcttttaaa
    26101 gcaaattctt ttgaacaacg aagttcccca actgttttat atatctcatc ttcaaggtga
    26161 gaaaattcat cttcacatcg taaaagtaca gactcttttc ctaaattcac ttcttctaag
    26221 tattgagtaa gattgtttat tctactcagt ttttgcttat ttgttctatg tttgattata
    26281 tatacaactg tagccattgt tgaaattata ccaaacgata tcactagaaa ataaaaaaag
    26341 tttttactcc aaaatgtact tttagaatat ccatgttttg ataaaatttc atttcctgtt
    26401 ttaaaatcct tatcactaga atttttcagt gattttagta tactttctgt agacttagga
    26461 ttgtactcat atgatgcacc aagagcctta gacagtacat tgtattcatt aaaagaagtt
    26521 atagttgtta gaattacact taataaaaaa gttataatta agcagaatat tataaaaaca
    26581 actgtactgt tgatatttct tggagttttc actagctgtc ctccattcta tatcctatgc
    26641 ctcttaatgt ttttatacaa ggtggatttt ttaatttttc tctaagacgc tttattgtaa
    26701 cagtaagagt gttatcattt acgaaattac catctacatc ccagagcatt tctagtaact
    26761 ttgtacgggt catagctcta tttttatttt ccataagact tagaagaagt ttatattctc
    26821 ctgctgtcaa aagtacttca acattatcta aatatgcttt gacttcaact ttattcaagc
    26881 ttatatttcc acatgtaata gtattgttag tatttgaatg agttcttcta agaactgcat
    26941 taattctgga ttgaagtact gagagcagaa atggtttaac cacatagtca tctgcaccca
    27001 tatctaatcc acgtataatg tctttttcat catcacggac tgtcaaaaat atcactggag
    27061 tatcttctat acttttaaca tattggcaaa actcgtatcc aataccatca ggtagattta
    27121 aatcaagcag aattaaatca atagttttat caaaattttt tttagcttca gcaatcgtat
    27181 tataacaaca tacagtgtga tttttctttt caagggaagt ttttattcca aatgtaattg
    27241 tatcatcatc ttctaaaaga agtattttag ccatttactt ttagtccttt cagtaattta
    27301 gttatttcat taactaagtt attagtttta tgtttaatat tttttatgtt agagatagaa
    27361 gttagagata gaaaaaatta tcatttaagt atataaactt taatttataa acttaggttt
    27421 atgctttaat tgaatctatt aaaagagcaa gagttgtttc aataaatttt tcctcatcta
    27481 tattaaagtt gttcaggtat gactttcctg ttacagatag taaattaaaa aatcctgtaa
    27541 gtgtaaatat tgatgaatac atgagagtag gtatttcaat atcatgccta atacttctat
    27601 cattttttcc aatttcaaac attccttgta tttcatcaaa cataaattta ttaaaagaaa
    27661 aaaacttttc tttaaacagc atatcagtat ccgatttttc agagtttaca ataccaatca
    27721 ttcccataag gcataataga gaaggttcta cagagtaaaa tttatgaaaa gcaaagtatg
    27781 aaagttttat tttttcaaac cctgttttgc cttttgcact ttctatttta acattatccc
    27841 aaagtctttt atatcctctt aagacaacag caaagaataa atcttcttta catgaaaagt
    27901 acttgtatat ggtgcgttta gtatattcaa cttcttttgc caactcattc atagttgtat
    27961 tctgaacctc ccatgactaa agtcacaggg ttcctgcttc atagaatttt gcatactaaa
    28021 atatgtctta ctaattctcc acaggccatc cccgtagttc ctacggttct tacataagtt
    28081 atttattttg aatcgttatt agtcttaatc cttcttttaa tatatttata cttgcattta
    28141 tatctctatc gtgagtttca ttacaactag gacaaatcca ttctcttata tttaagttct
    28201 taacttcctc gtttttatac ccacatttat tgcatatttg tgaacttgca aagaatttac
    28261 ctactttata caatttgtct accataccaa ttagccttgt attctaattg acgaataaat
    28321 tctgaccatg atacatcaga aattaagcga gatagtttat gatttttaat catattcttt
    28381 acttgtaaat cttctatgca aataatatca ttctctttta ttaatttagt agata
//
LOCUS       DAMJWO010000053        28139 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.054, whole genome shotgun sequence.
ACCESSION   DAMJWO010000053 DAMJWO010000000
VERSION     DAMJWO010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28139
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.054"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            191..820
                     /locus_tag="PC366_002357"
     CDS             191..820
                     /locus_tag="PC366_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577864.1"
                     /translation="MNKYLLINPVAERMYGEKFHLIKANLIKKGYIIAECEPQLEYVK
                     KQYKEYTKKTENTMLDCRCPESISLLKRNNLINNFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLVVTCPCTQLRDFASEKFKDKGNAMFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGFEDKYDIVEMFYCKDGCNNGDGL"
     gene            821..1603
                     /locus_tag="PC366_002358"
     CDS             821..1603
                     /locus_tag="PC366_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577865.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAINTAIGVPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVEAYE"
     gene            1596..2474
                     /locus_tag="PC366_002359"
     CDS             1596..2474
                     /locus_tag="PC366_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577866.1"
                     /translation="MNNLVCDSGYIIRNLYKSYKVDNEEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLEGINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     AFHNQRKNTILNKVLRKFKHNKRIIGKIINDNFRSLETNDNLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLLMDEPFSALDYFTRIDMQN
                     EVIKIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKIKEFNIEDGYNRDLTSEYYI
                     KLKKDILMTMKSNKDI"
     gene            2507..3466
                     /locus_tag="PC366_002360"
     CDS             2507..3466
                     /locus_tag="PC366_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2577867.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSVDVALIAGPAALKAMKSGSKLVANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYA
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            3780..4472
                     /locus_tag="PC366_002361"
     CDS             3780..4472
                     /locus_tag="PC366_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2577868.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSHIRRVYGEYSPKIDERIVELDGLKFYPERLELELNGENLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     VRGLGYKLNKNW"
     gene            4482..5486
                     /locus_tag="PC366_002362"
     CDS             4482..5486
                     /locus_tag="PC366_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2577869.1"
                     /translation="MKLFLKDYKGYIFIYYIGIVMTIIYCNLMKFISFGESLYILLFS
                     SFILLCFLIYKYYKNREVYNLFEKGIHSLEESFLYLGSSFLGRNISVILKQQHKLYQS
                     MIQEHKKIHSEHLTFINQWIHQMKTPISVISLQLQDYEGEEVTENIRKEIDRLNKGLD
                     MAMHFARADNFQKDFIVEKAKLNEIVSSIVNEEKRLFIKSGMIPKIQVDKFTYVYTDV
                     KWMKFIIGQLITNGVKYSKDYSNYLTIKSEENNKYVILSIIDEGIGIVSKDLKRVFDP
                     FFTGENGRKFGESTGMGLYLVKKVCDDLGHKVSIKSEVGKGTEVSIYFNKDVNSLIKM
                     "
     gene            5734..6585
                     /locus_tag="PC366_002363"
     CDS             5734..6585
                     /locus_tag="PC366_002363"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDF2577870.1"
                     /translation="MSLDVIFILKSVIIAIVEGFTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVIEFFKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQA
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSIMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAVYRIIMGVVLAVLA
                     FTNIISV"
     gene            6689..7435
                     /locus_tag="PC366_002364"
     CDS             6689..7435
                     /locus_tag="PC366_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001637630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577871.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKGKNPLLLRGEELALFRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDERLNEVSTILGIKDLLGKRTFEVSGGQAQRTAIARALINN
                     PSILLADEPTGNLDSKSSKVVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     SIYNEIYKGSSREQFYQEIMDVLTLLGGDN"
     gene            7435..9351
                     /locus_tag="PC366_002365"
     CDS             7435..9351
                     /locus_tag="PC366_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577872.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDL
                     DVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVVMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSIFTYFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITST
                     DQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMMFIENNLKKENVDYTRTNGEFKTVFPKKSDFNVRIMKESKYLEITETIG
                     VKPISFEDNECISLLSSSLPGNNNVKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFNNESGMQPYLFFSKELMIGT
                     GKLIYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKA
                     STIEIGIVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFLIVR
                     NNYLKEIRLNLVNF"
     gene            9630..10547
                     /locus_tag="PC366_002366"
     CDS             9630..10547
                     /locus_tag="PC366_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDF2577873.1"
                     /translation="MMILIQSRGKMKCKELSEELEVSERQIKSYKMYLEQAGIFINST
                     PGIYGGYEIDKCNSISLIKLLDSEVSILDMINSQLEYNNDIYKNEFNNIVEKIKAVLN
                     TGEKSDTYMDYFTVQAQRNCDYKSEKNKCNEIIRAYTTKHKFWIEYYSLNSGNSERIV
                     HPYGLFNYKSDTYMVAFCEKRFKFIDFKLCRIKDYKVLEEKYNVDKSFSWDEYSKNSI
                     GIYKGEEINVVIKISHPFSIIIKEKVWVNNQQIIEYDDKSIMFKAKMRGYEEIKSWIL
                     SMGAYVEVVEPDRLRNDILSEIEKMKKIY"
     gene            10625..11362
                     /gene="cas6"
                     /locus_tag="PC366_002367"
     CDS             10625..11362
                     /gene="cas6"
                     /locus_tag="PC366_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HDF2577874.1"
                     /translation="MKMKIEFSTGCIPISYNSLFMSIIKEAIRKSNEDYYKNMYYYKE
                     KNNKKTKNFTFSVYIKKYSIEGDNFIIEDKVILNISTPDLELGFHIYNGLMTSKKCLY
                     KAYELTRIRIDLSREKKVTEERVLFNALSPICVKSKEGKFLEITDDRYIEELNYITNE
                     VVKNYRGNGLKRKLEFENIGLKKIVVKESLREFKKITGKEYQYINGYKGKFILKGDID
                     DLNLIYNLGIGFRRAQGFGDVDILEWR"
     gene            11368..13245
                     /gene="cas8a1"
                     /locus_tag="PC366_002368"
     CDS             11368..13245
                     /gene="cas8a1"
                     /locus_tag="PC366_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas8b1/Cst1"
                     /protein_id="HDF2577875.1"
                     /translation="MKLRVYRGDWFFNMGIVGFLNIIKKADKQAEIFIMEDYIEFDSL
                     FLENFHEYYFNYFMDEYDVSKRIKKNIDYSINFIKSKPDRIKDGIKKIKDSVKQQNDK
                     IKKFDEEKFNLIKEKLDSMSKIKSYDEFDSLEALVDETIDIFKIKSINDRLTANLYKY
                     VVQDNYFGQVSFFNVAKAKLDLDGLKQIMFNDYLRQIIYFGELADLLEENDYDKLKNY
                     LNDRLNSIAKDINEKKVSKSSINTIEKIMKEINKNFIKKNKSIEDIKEYMDSLEVCEM
                     CGLYKGILDEYSESNFAPLGVSTNNARNMFWNQAYVPSICDICKLILFCTPAGATYTR
                     KNYLINEENEFYLFVNMDTSINELFERNNSLKAQKSEYSDSKDENPFNQLIKSIVEEN
                     TLKSEWQLRNILFVEFKASIDSKKCKINYFNIPTYLAKFFTDKYANKKIQSIYDYKLK
                     SNVLDLLLKNRDLKHLTNNILRNKVKNDMESNNKSNISGIDCFRVVQLRALINSYKKG
                     VYKMDSKNLEKNDEKLRIIYYLGCDIHDYFVNKNSKNKIDGVSYKLLNSVKVGNKSDF
                     MDTIIRVFMSAEKQIPAFILDIEIEKDLDFESIGHAFISGLISGKYEGKDKLPNEKEE
                     K"
     gene            13247..14161
                     /gene="cas7i"
                     /locus_tag="PC366_002369"
     CDS             13247..14161
                     /gene="cas7i"
                     /locus_tag="PC366_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HDF2577876.1"
                     /translation="MKRGLTFTVIAQAQSLNYGEGIGNISELKKLSRDDGNIYTFASR
                     QCLRYDIVRLAAELFNWNLQVVDKEKGTIQFKDNISIRESEEMDLFGYMKTNKKDEKD
                     KKGGSLTREATVRLSNAISLEPYRSDMDFLNNKGLADRIGEHPNLANIEQHLSYYTYT
                     VTIDLSKIGKDGDIELDNKEKCRRVVEFLEIIKVLNRNIRGRQENLSPLFVVGGVYEI
                     ANPFFLGRIKLKGDKNGFKINKQAIEEVIQGTFLGKDLKEFTYVGMVDGVFINKEEFK
                     GLFEDNFLSVDKFFGQLVKEVKEYYGVN"
     gene            14163..14864
                     /gene="cas5b"
                     /locus_tag="PC366_002370"
     CDS             14163..14864
                     /gene="cas5b"
                     /locus_tag="PC366_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5"
                     /protein_id="HDF2577877.1"
                     /translation="MKVLKLDLFQETACYKKPFAMKITETYPLPPYSTINGLIHKILN
                     ATEYIPFNISVQGTYESIFNNYQTTYFYKKDSITSMPMNSHMLLNVNLIIHIGGDFDL
                     LEEIYDSLLNYDEHLSLGRKEDLVRINDIRFVEVNKFEVDEDIQLDDYENYKLSECNI
                     RMPIYIPKTSLQDTDIDGISYRLNNYYDNNAVEDKKRVWNKVDSYYVEDGNTISIGDI
                     LLDNEGDLLYFNNIN"
     gene            14875..17196
                     /locus_tag="PC366_002371"
     CDS             14875..17196
                     /locus_tag="PC366_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HDF2577878.1"
                     /translation="MLYAKSNPVETLREHTDELLKQMNVLRESYGKNINSLDFLEEEI
                     FWQLLDFVIEFHDIGKAFSPFQELIKSRMDTKINEPKIVTHLENNVGHNYLSPAFIDY
                     SYIDRKKNKELRAVLNQVIVYHHERDIFIDKDFKNLIQKILDEDLINKVYELQREFKV
                     RYPIKTEKLSKVYLQSVEKRIDKNHKYYNLYIMLKGILHRLDHSASAHEVVECNNVIN
                     IGEQTENYLMKEFGSLREAQSFAKSNRNKNIILIASTGMGKTETALIWIDKDKAFFTL
                     PLRVSINALFDRAKNIIGVGEANDTFLGLLHSTAIDYLEESNQENSSEIVDLAKLLSC
                     KLTFSTIDQIFKFPFLYRGYEKVYSTLAYSKVVIDEIQAYSPEIAAVLVKGIEMIHKI
                     GGRFMIMTATMPTIYIDELKKRGVMNSNLADLTCNTEKIRHCVSIVENSIDENLGKII
                     QSGMNKKVLVIVNTVKSAVEKYELIEEIVKPKGIDVNLNLLHSMYIQEDRAKLEKYIK
                     EFADSDSNGIWITTQLVEASLDIDFDELHTENSTLDSLFQRFGRCYRSREYEENSPNI
                     FIYTEKATGIGSIYDKDIVEKGLELLKTFINGKECVKMKEKYKVEMVKILYSKESLEG
                     TAFEKRFTSALNILDTITPYSLGSKDAQNILRNIEGYTVIPEDIYNKIEETLIKDYEE
                     LGQELINAYSNDDRQLINKIKSKRKKARREIIKKTVNLPIYKAKQNVIDIQVKGLEDL
                     KILLYKYDIHENKHTKQIFGKGVLISNEIDQFI"
     gene            17211..17762
                     /gene="cas4"
                     /locus_tag="PC366_002372"
     CDS             17211..17762
                     /gene="cas4"
                     /locus_tag="PC366_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HDF2577879.1"
                     /translation="MWLKFTKEGDFVPIDLEVLKVQGVKINYYYVCKRKLWLFSKGIT
                     MEQNSSRVLSGKIVHEDSYKRMKNKEMLIDDILKLDIIKDEYVKEVKISSKMKEADEM
                     QLYYYLYYLKNSMGIEKKGTINYVKEKKQEELILTEEKEKIIENTLININEINMQLSP
                     PKIEKKHYCTKCAYYEFCFVKEE"
     gene            17765..18745
                     /gene="cas1b"
                     /locus_tag="PC366_002373"
     CDS             17765..18745
                     /gene="cas1b"
                     /locus_tag="PC366_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1"
                     /protein_id="HDF2577880.1"
                     /translation="MYKDYYIISNGNIKRKENTIYYYNLEGEKKILPVEQVDDIHIYG
                     EVDLNTKLINYISKYGVMLHFYNYYGYYSGTYYPRKKNVSGFSLVCQSACYLDKNERL
                     YLAKSFVESASYHILRNMRYYKVDESLIDTIKDELNDLNDVKEISELMGKEGRIRKTY
                     YKSFNQILKDDFEFYKREKRPPKDPVNTLMSFGNSIMYTNVLSEIYKTQLDPTISFLH
                     EPSTKRFSLSLDIAEIFKPIIVDTIIFSLINNKRINKNDFEYQDKICYLSEKGKKKFL
                     QEFENKMQTTIKHRNLNRKVSYRMFIRLECYKLIKHFINDERYKVLKVWW"
     gene            18748..19014
                     /gene="cas2"
                     /locus_tag="PC366_002374"
     CDS             18748..19014
                     /gene="cas2"
                     /locus_tag="PC366_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HDF2577881.1"
                     /translation="MFVIVTYDIVEARSLNRIRRILRKYLTWTQNSVFEGNITDGKLH
                     KCISEIENIIDNSEDSIYVYEIKNPNSIKKKCYGIDKYSDEMFI"
     repeat_region   19198..20815
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=19198..19226
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaat"
     gene            21005..21433
                     /locus_tag="PC366_002375"
     CDS             21005..21433
                     /locus_tag="PC366_002375"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDF2577882.1"
                     /translation="MIKKLNNKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEY
                     IPISDTFVYDDGDEIKGFISIIDKSFIGALFIEPKYQNLGIGGKLLDYATKKYKSLSL
                     AVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK"
     gene            complement(21889..22668)
                     /locus_tag="PC366_002376"
     CDS             complement(21889..22668)
                     /locus_tag="PC366_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577883.1"
                     /translation="MKVNENNINNIDEELDELSRKVYLESPDFWISISDKIIDKVFDE
                     MLLFFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYL
                     LSLNKGNNLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDIT
                     YKFSSKEAEPIEMSSEVSSIRCCNCDELLEDITLNKLYNLCKIQNCNNCGSNLTKVGI
                     IAKKKMNFDENTEKFKDVSTSYCCGNCDSEINLSQREHFKI"
     gene            22992..23537
                     /locus_tag="PC366_002377"
     CDS             22992..23537
                     /locus_tag="PC366_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HDF2577884.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRRNL"
     gene            23569..24705
                     /locus_tag="PC366_002378"
     CDS             23569..24705
                     /locus_tag="PC366_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HDF2577885.1"
                     /translation="MKEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQ
                     CNLIIAGGFESSSLQPMRTYHKNDKRYNTNNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIERADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMP
                     PILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKTKIINTCTIGTDATLSPT
                     SAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIERYNIFGGALAYGH
                     PYGASGAIITLHLLKALEKTKGRYGICSIAAAGGLGSALLLERV"
     gene            24709..26100
                     /locus_tag="PC366_002379"
     CDS             24709..26100
                     /locus_tag="PC366_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HDF2577886.1"
                     /translation="MNYYELLRIKKERHKNKNFLIIDGEKYTYENILSYSEQLGKQIS
                     LGENISILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNFSIFNPKFNLYMYQYKNLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRTIKQYNVTNIYLIPTKLQLLVKHLKEPVLKVVSIFTGSQLLFEYTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRPFPGIDIYIRGGKIFVNT
                     EYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDIVNIGGFKVSSAKIENEVKKIPQIE
                     DAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            26176..27051
                     /gene="dpsA"
                     /locus_tag="PC366_002380"
     CDS             26176..27051
                     /gene="dpsA"
                     /locus_tag="PC366_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HDF2577887.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYALDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTI
                     PECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEVGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            27054..27644
                     /locus_tag="PC366_002381"
     CDS             27054..27644
                     /locus_tag="PC366_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HDF2577888.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(27852..28052)
                     /locus_tag="PC366_002382"
     CDS             complement(27852..28052)
                     /locus_tag="PC366_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577889.1"
                     /translation="MKKLKTISIFSLIISVILTIGGIGIVTYYVDNLFIRGLSVFVLI
                     MSSSFVSTTVRLIFEESKRYKF"
BASE COUNT        11310 a         2689 c         4685 g         9455 t
ORIGIN      
        1 attattagta agatgtatgc attattaatt aaaataaatt acatatacta tttaatattt
       61 catttaaaat attaaaaaat gtagataaaa attgttttat taaggaaaaa ttaatatatt
      121 gacaaaattt aagtgctcat ttaaactatt aattgataat aatattcaat attaaataat
      181 aggaggcgtt atgaataaat atcttctaat aaatccagtg gcagaaagaa tgtatggaga
      241 aaagtttcac cttattaaag caaatttgat aaaaaagggg tacataatag cagaatgtga
      301 accacagtta gaatatgtaa aaaagcagta caaagagtat acaaaaaaga ctgaaaatac
      361 aatgttggat tgtagatgtc cagaaagtat aagtctttta aaaagaaata atttgataaa
      421 taattttgaa gtacctatga tagaaccaat attagtaagg acttgtaggg ttttatacga
      481 taaatatata aaaagtaaag atgatatgtt ggtagtaacc tgtccatgta cacaattaag
      541 agactttgca agtgaaaagt ttaaggataa gggtaatgct atgttttata catggaaaga
      601 gtttgctgaa caagaaggtg taaaatcact tggaaaaata gatgaatcac caattccatt
      661 aggatatttc aaagatactt ttgaaaaagt tcttgaagta tcaagtgaag acgaaatatt
      721 aagtgaaata caaaaaataa gaaatggctt tgaagataag tatgacatag tagaaatgtt
      781 ttattgtaaa gatggttgta ataatggaga tggtttgtaa atggtcaata aatttaataa
      841 taagttttta aggctagtaa agagtgttct gatatttttt ataattcttt tattatggaa
      901 aattacaaat tatcttggta tttggagtga ttatatatta ccatcacccg aaaaggtata
      961 tagtacattt ttaaatatga taagtgatgg ttcaatattt attaatgtat atgcaagtat
     1021 gaaaagagtt ttgataggtt ttgcaataaa tactgctata ggtgtgcctt tagggatatt
     1081 ctttggaatt tatagtggag tatacgaata ctttaaatct ctaataaatt ttttaaggaa
     1141 tacacctccc cttgctttaa taccaatgct tatattatgg tttggtatag gagaggaatc
     1201 aaaaattata attatagttt tagcatcctt tttcccaatc tttacaagca cattgaaagg
     1261 gattaaaaat tgtgactcaa aactgattga agtgggtaga gtatttgagt tttcaaagct
     1321 tcagataata tttaaaataa taataccaaa tgccattctt gatattgctg ttgggttaaa
     1381 gttagctctt ggatatagct ttagagcaat tattggggca gaacttgtag cagcttcatc
     1441 tggtcttgga tacttgatat ctgatggaaa agaaatgtct agaacagatg ttgttattgt
     1501 aggtataatc gtaattggac ttttaggaat aattacagat tacatatttt cgattattgt
     1561 gaagaaggta agtaagggaa agatggtgga agcatatgaa taatttagta tgtgactctg
     1621 gatatataat tagaaattta tataaaagtt ataaagttga caatgaagaa catgtagttc
     1681 ttagtgatat ctctttaaac atagatagaa accatataac agtaatttta ggtgaaagtg
     1741 gttgtggaaa gactaccttg cttagagcaa ttgcatcact tgaaggtata aatagtggtg
     1801 agattaggtt tattaatgat aataaagagt atagacctaa tgttggtttt gtttttcagg
     1861 agagcagatt aatgccttgg ttaaacgtaa gtgaaaatat agcttttcat aatcaaagaa
     1921 aaaatactat tttaaacaag gtgcttagaa aatttaaaca caataaaaga attattggta
     1981 aaattataaa tgataatttt agaagcttag aaacaaatga taatttgaac aaatcaaata
     2041 aatataatag gaaaagtaat attgatgtag aaaaatatct taagatgatg aacttgcaga
     2101 aatttaaaaa ctcttatcca aatgaattgt caggaggtat ggcacagaga gtaagcatag
     2161 ctagagctct ttctttcaat ccagatatgt tgcttatgga cgagcctttt tcggcattag
     2221 attattttac aaggattgat atgcaaaatg aagttataaa aatacataag tcaactaata
     2281 aaggcgtaat atttgtaact catgatattg atgaagcgtt aaagataggc aaaaaaatag
     2341 ttgttttcac agacgaaaga aaaataaaag aatttaatat agaagatggt tataatagag
     2401 atttaacttc agagtactat attaaattaa aaaaagatat tttaatgaca atgaaatcaa
     2461 ataaagacat ttaaagaaat taataatatt ttaaggagta gagtaaatga aattaaaaaa
     2521 gctattgata ggtataacga tattaacact tgcaacagca tctttagctg gatgtgctaa
     2581 aaaaaataat ggagaaaaac tttcagaaat aaatttaact tatgtaaaat caccattaaa
     2641 tgttccttct ataattcaga aacaggatga tttatttgga aaggaattta aaaaggataa
     2701 tataaaagtt aactttcacg aaattactac aggtccagag caaacacagg ctttagctgc
     2761 tggagaaata gacttcttac atgcactagg tggtacgtca gctttaatag ctgcatctaa
     2821 tggagtagag ttaaagatat taaacactta tagcaggtca ccaaaaggat ttatgatttt
     2881 gactaataat aattcaataa aatcagcagc agatttagta ggtaagaagg tggcaggtcc
     2941 aaaagggact atattacatc aggtattgat ttcagcactt gataaagaag gattaagtat
     3001 ggatgatgtg gaatttgtta atatgggtat tccagaagca tcagcagctc tttctgatgg
     3061 tagcgtagat gttgcattga ttgctggtcc agcagctctt aaagctatga agtcaggtag
     3121 taaacttgta gcaaatggtg aaggtttagt agatggtata atagtaactg ctgttagcac
     3181 agactttgca gagaaacacc cagaaatagt tgaaagattt atgaaggttg aaaaggaaac
     3241 tttagaatat gtaaataata attttgatga agctatggaa aaagtagcta aagaagttga
     3301 tttaagtctt gaagaaacta aagaattata tgcttggtat gattttagtt tagatataac
     3361 agataaagat atatcttcgc ttgaagatac acaagacttc ttaataaaaa ataagttaca
     3421 agagaaaaaa gtgaatataa aagaattaat ctataatgct aagtagaaac tatgctaaaa
     3481 taatactaag taagaaatat aataaaagtt taagttacct tattaaggta actttttcta
     3541 ttttgaatta gtaatttcaa tttattttag aatgattagt tgataataat gattaattaa
     3601 tcataaaaag atactttttt atagagtttt attaagatgt ctaataatat ggttatactt
     3661 atgaagtcag taattgtgaa gttaataata tgattaaatt tatatattgt aaaaagatta
     3721 taatatatta aaattggact gttatatgat gagtaaatag gtatattagg aggaattata
     3781 tgagttataa agtatatatt gtggaagatg atatatcaat aagtacatta cttaaagatt
     3841 atattgagaa atatggattt gaagtgattg ttgaagagaa ctttgatgat ataatgatta
     3901 catttgaaag ttttaagcca cacttagttc tattagatgt aaatttacct aaatttgatg
     3961 gtttctactg gtgtagatgt attagacaac agtcgaattt acctataatt tttatatcag
     4021 ctagagatgg caatgtagac caaattagag ctttagaaag tggagcagat gattatataa
     4081 caaaaccttt ttactatgat gtagtaatgg caaaaataaa gagtcatata agaagggtat
     4141 atggtgaata ttcacctaaa atagacgaaa gaatagtgga gctagatgga ttaaagtttt
     4201 atccagaaag gttagaacta gaattaaatg gtgaaaatct aattataact aaaaaagaag
     4261 gtatactgat tgaatgtctt atcaagagat acccaaaagt agtaagtaga gattatcttt
     4321 tagaaaagat atgggatgat attgagtttg tagaagaaaa tactttaaat gtaaatgtta
     4381 gcaggataag gaaaagattt gaggaattag gtatagataa tgctgttcag actgtccgag
     4441 ggttaggata taaattaaat aagaattggt aaggagaaag tatgaagtta tttttaaaag
     4501 attataaagg ttatattttt atatattata taggcatagt tatgacaatt atttactgta
     4561 atcttatgaa gtttattagt tttggagaga gtttatatat tcttttattt agttctttta
     4621 tattgttatg ttttttaata tataagtatt ataaaaatag agaagtatat aatctgtttg
     4681 aaaaaggaat acattctttg gaggagtcat ttttgtattt aggaagctca ttcttgggga
     4741 gaaatatatc agttatttta aaacaacaac ataaattgta tcaatcaatg atacaagagc
     4801 ataaaaagat acatagtgaa catttaactt tcatcaacca atggattcat cagatgaaaa
     4861 caccaatatc agttataagc cttcagcttc aagattatga gggagaagaa gtaactgaaa
     4921 atataagaaa agaaatagat agattaaata aagggttaga tatggctatg cattttgcaa
     4981 gggcagataa ttttcagaaa gactttatag ttgaaaaagc caaattaaat gaaattgtat
     5041 ctagtattgt aaatgaagaa aaaaggttat ttataaaaag tggaatgatt cctaagattc
     5101 aagtagacaa atttacttat gtttatacag atgtaaaatg gatgaaattt ataataggtc
     5161 aattaattac aaatggagtg aaatattcta aagattatag taactaccta actataaaat
     5221 ctgaagaaaa taataaatat gtaattttaa gtataataga tgaaggaatt ggaattgttt
     5281 ctaaagattt aaaaagggta tttgacccat tttttacagg agaaaatggt cgtaagtttg
     5341 gagaatctac aggtatgggt ctttatctag taaaaaaggt atgtgatgat ttaggtcata
     5401 aagtaagtat aaaatcagaa gtaggaaaag gtacagaagt ttcaatctac tttaataaag
     5461 atgtaaatag tttgataaag atgtaaatta tctgttacaa tagggttttt agttaattgt
     5521 acttttttat tatacaattt attaaatgaa atattcatag ttaaataatc aaaatttaag
     5581 agagtttatt tgcaaacctt acatagatgt aaggtttgtg taatgtttgc agatagttaa
     5641 attttctaat ctaaattaca attaatataa gaaataacat gagagaaata acataaaaaa
     5701 agaaattttg taaaaaagga aggatgttta ttgatgagtt tagatgttat ttttatattg
     5761 aaatcagtca taatagctat agtagagggg tttacagaat ttattccagt ttcatctaca
     5821 ggtcatatga ttttggttgg taatttaata gattttaagg ggcaatttgc tgaaatgttt
     5881 gaggttgtaa tacaacttgg ggctatatta gcagtagtag tactttattg gaaaaagata
     5941 aaagatagcg ttatagaatt ttttaaattt atatttactg gcggaaaaga aggaaagatt
     6001 ggttttagat ttggaatgaa tgtaattata ggttgtatac catttgcgat tataggagtt
     6061 ctattttatg ataatataaa atcattgttt aatttacaat ctgtaattat aggatttata
     6121 gtgggtggga ttttattatt agtagtagaa actttgttta gaaaaaagaa tcattcaaca
     6181 gataatatag ataaaattac tccaatacaa gctttaaagg ttgggacatt acaagttttg
     6241 tctgcatggc caggtatgtc aaggagtgca tctactatta tgggtggatg gatagcagga
     6301 cttaattctc ctacagcagc tgagttttct ttctttttag cagtaccagc tatggtggct
     6361 tcttcaggaa aagatttatt tgaatttgat tattcaataa tgacaccaac attgtggatt
     6421 gctttggtag ttgggtttat agtagctttt attgtatcaa taatagttat ggaaaaattc
     6481 gtgaattttt taaagaaaaa accaatgaga gtgtttgctg tatacagaat aatcatgggt
     6541 gtagtacttg cagtattagc ttttactaac ataattagtg tatagaaaaa atagatttat
     6601 tatctataaa aattaaacta agataaatta taattaacaa ttatatatat gttatttcaa
     6661 aaattaaatt aggaaggata gttaaataat gaaaatttta actgtaaata atttaagtaa
     6721 agtatatggt aaaaaaataa ttttcaacgc attaaatgac ataaatttta gtatagaaga
     6781 tggagaattt gtaggaatta tgggtccatc tggtagtgga aaaactactc ttttaaatat
     6841 gatttctact attgacaagc caactacagg aactatggaa ttaaagggaa agaatccttt
     6901 attgttaaga ggtgaggaac ttgcattatt tagaagaaga gagttaggtt ttgtatttca
     6961 ggattttaat ttattggata cattaactat aggagaaaat atagtattgc cattgacatt
     7021 agataaggtc agtgtaaaag agcaagatga gagattgaat gaagtatcta caatattagg
     7081 tataaaagat ttattaggaa aaagaacttt tgaagtatca ggtggtcaag ctcagaggac
     7141 tgctattgct agagcattga ttaacaatcc atcaatactt ttagcagatg aaccaacagg
     7201 taatttagat tcaaagtcat caaaggttgt aatggagcta tttcaaaaga taaataaaga
     7261 aaataaagtt actactatga tggtaactca tgacccatta gcagcgagct actgtagtag
     7321 aatcttattc ataaaagatg ggtctatata taatgaaata tataagggta gtagtagaga
     7381 gcagttttat caagagataa tggatgtact tacattattg ggaggcgata actaatgaat
     7441 ataaaacagt ttgctattaa caatatttca agaaatatta aagcgtattt aggatactta
     7501 gcaagtattg ttatatcatc ttcactgcta ttttctttta ttatgtttac aagtcatcca
     7561 gatttagatg tatctcaatt tcctgattat ttaaaagaag gtctcaagat gagtaagata
     7621 attgcatatc tattcttatt cttctttgtg ttttattcag ttagtgtgtt tcttaaaagt
     7681 agatataaag aatttggaat actttatatt acaggtatat caaaacgcca agtaatgaaa
     7741 ttaatcttta tagaaaatat gataataaat atagtatctt ctgtaattgg aataataata
     7801 ggcttaatct ttgcaaagat atttttagtg gttatgtcta cttttttaga attatcgcca
     7861 ttaaaattct atataccatt taatgcgata ttgtctactt taatctattt tatgatttta
     7921 gctgtattaa catcaatatt tacttatttt atagttaaag aaaatcaggt gttgaagtta
     7981 cttaaaggta caaaaactcc aaaaccagag cctaaaacat cactaatgct tgctatatta
     8041 agtatttgtt tgtttataat agcgtattat aatgctatta cctcaaccga ccaatataca
     8101 acatatctgc gcttagttcc agttacatcc cttactatag tagcaactta cttgttcttt
     8161 tctcaattta gtgtattttt tatgaagaag ctaaaactaa acaagagatt ttatagaaaa
     8221 aatacaaata tgctttggat ttcgaacttg atttataagg taaaggataa tgctagaata
     8281 tttttcttga taactataac ttctgcagta gcatttactg ctataggtac agtttattcc
     8341 ttttggaaag atgtagagcg tcaaattaat ttaatatatc ctaacacaat atattattca
     8401 acaatgacat tgcataatga ccctaaaaag cctgatagca aagaaaaaga caaggaaaga
     8461 atgatgttta tagaaaataa tctaaaaaaa gagaatgtag actatacaag gactaatggt
     8521 gaatttaaaa ctgtatttcc caagaaaagt gattttaatg tcagaattat gaaagaatct
     8581 aagtacttag aaattacaga aactataggg gttaagccta taagttttga agataatgaa
     8641 tgcatatcat tattatcatc aagtttacca ggaaataata acgtcaaaga aaatattatt
     8701 gtagggaata gaggtttaaa ggtggcaaaa caagtggaag aatgtgttat gccagcatat
     8761 tacaaaaata tgtatgtggt aaaggataat ttttatgata gtatagaatc aaaatttata
     8821 gtggatagat ttactgcatt tgaagtagag gattcaagta aaactataga gatatgcaga
     8881 gaatttgaaa ataaatttaa taatgagtca gggatgcaac catatttgtt tttctctaaa
     8941 gaattaatga taggaactgg gaaattaata tattctacat ttatattttt agcaatattt
     9001 ataggtttaa ttttctttgt tactacaagt agttttttat ataataaatt ttatatggat
     9061 tgccaagttg ataagaaaaa gtatgagcaa ttaaataaat tggggatgac atataatgag
     9121 attaaaaaag cttcaacaat tgagattgga atagtatttt tgtttcctta tgtagtggct
     9181 gttatacatt caatatttgc ccttactgca ctgaaaaatt cttttgatat agaagtagca
     9241 tcatcagctg ttttggtaat gggaagcttg ttcttggttc aaatagttta ttttttaatt
     9301 gtaagaaata attatttaaa agagataagg ttaaatttag tcaattttta gttactatta
     9361 ttaaatgata ataaaaaggg tttaaaatta attaatatta ctggaattat agatgtttat
     9421 tttttcagta atatttttta ttgtattaac tattaaaatt ttgtacaaat ataaaatata
     9481 atatggtaaa tgtcaaaatt ataaaaaaat tctacttata taaaatataa agaggttata
     9541 tgtacatatg tgtagaaata aataataaaa atatcaatta atgttattag ggggggttac
     9601 tcattagtaa attagctaat acacttagaa tgatgatatt aattcaaagc agaggcaaaa
     9661 tgaaatgcaa agaattatca gaagagttgg aagtaagtga aaggcaaata aaaagttaca
     9721 agatgtattt agagcaagct ggtatattta taaattcaac acctgggatt tatggtggtt
     9781 atgaaataga taaatgtaat agcatatcat taattaaatt attagatagt gaagtttcaa
     9841 ttctagatat gataaattca cagttagagt ataataatga tatttacaaa aatgaattta
     9901 ataatattgt agaaaaaata aaagcagtat taaatacagg agaaaaaagc gatacatata
     9961 tggattattt tacagttcaa gcacaacgta attgtgatta taagtctgaa aaaaataagt
    10021 gtaatgaaat aattagagca tataccacaa aacacaaatt ttggatagaa tattattcat
    10081 taaattcagg aaatagtgaa agaattgttc atccatatgg tttatttaat tataaatcag
    10141 atacttatat ggtagctttt tgtgaaaaaa gatttaagtt tatagacttt aaattatgta
    10201 gaattaaaga ttataaggtt ttagaagaaa aatataatgt agataaaagt tttagttggg
    10261 atgaatatag taaaaatagt ataggaattt ataaaggaga agaaattaat gttgttataa
    10321 aaattagtca tccattttca ataattataa aggaaaaagt ttgggttaat aatcaacaaa
    10381 tcatagaata tgatgataaa tctataatgt ttaaagctaa aatgagaggt tatgaggaga
    10441 taaaaagttg gattttaagt atgggagctt atgttgaggt tgtagaacca gatagactta
    10501 gaaatgatat attgtcagag attgaaaaaa tgaaaaaaat ttactgattt tttcaaataa
    10561 tttatacttg gaccaatata cttcacggtc tagtgttaat atattaattg agagaggtga
    10621 tattatgaaa atgaaaattg aatttagtac aggttgtata ccaatatctt ataattcgct
    10681 ctttatgagt attataaaag aagcaataag aaaatctaat gaagattact ataaaaacat
    10741 gtactattat aaagaaaaga ataataaaaa aactaaaaat tttacatttt cggtttatat
    10801 aaaaaagtat agtattgaag gtgacaattt tattatagaa gataaagtaa tattaaatat
    10861 aagtactcca gatttagaat tgggttttca tatatacaat gggttaatga cttctaaaaa
    10921 atgtttatat aaagcctatg aacttacaag aattagaatc gatttatcaa gagaaaagaa
    10981 ggtaacagaa gaaagggtac tatttaatgc attgtctcca atctgtgtaa agtctaaaga
    11041 aggaaaattc ttggagataa ctgatgatag atacatagaa gaactaaact atataactaa
    11101 tgaagtggtt aaaaattata ggggaaatgg attaaaaaga aagttagaat ttgaaaatat
    11161 aggtctcaaa aagatagtag ttaaagagag cttaagagaa tttaaaaaaa taacaggtaa
    11221 agagtatcaa tatattaatg gttacaaagg taaatttata ttgaaaggtg atattgatga
    11281 tttaaatctt atctacaatc taggaattgg ttttagacgt gctcagggat ttggagatgt
    11341 agatatttta gaatggaggt gagataaatg aagttaagag tttatagagg agattggttt
    11401 tttaatatgg gtatagttgg atttttaaat ataataaaga aagcagataa acaagctgaa
    11461 atatttatta tggaagatta tatcgaattt gatagcttat ttcttgaaaa ctttcatgag
    11521 tattatttta attactttat ggatgaatat gatgtatcaa aaagaattaa aaaaaatatt
    11581 gattacagta taaattttat taaatctaag cctgatagaa tcaaagatgg aattaagaaa
    11641 attaaagata gtgtgaaaca acaaaatgat aagattaaaa aatttgatga agaaaaattt
    11701 aacctgataa aagagaagct agatagcatg tctaagataa aaagttatga tgaatttgac
    11761 agtttagaag ctttagtaga tgagactata gatatattta aaataaaatc aataaatgac
    11821 aggcttacag caaatcttta taaatatgta gttcaagata attattttgg acaagttagt
    11881 ttttttaatg ttgctaaggc gaaattagat ttagatggat taaaacagat aatgtttaat
    11941 gattatttaa gacaaattat atattttgga gagttagcag atttattaga agagaatgac
    12001 tatgataagt tgaaaaacta tttaaatgat agattaaata gtatagctaa ggatataaat
    12061 gaaaaaaaag ttagtaagtc tagtataaat actatagaaa aaattatgaa ggaaataaat
    12121 aaaaacttta taaagaaaaa taaaagcata gaagatataa aagagtatat ggatagttta
    12181 gaagtatgtg aaatgtgtgg tttatataag ggaatattag atgaatactc agaaagtaat
    12241 tttgctccac ttggagtaag caccaataat gctaggaata tgttttggaa tcaggcgtat
    12301 gtaccatcaa tatgtgatat ttgtaagcta atattgttct gtactccagc aggggctact
    12361 tatacaagaa agaattattt aattaatgaa gaaaatgagt tttatttatt tgttaacatg
    12421 gatacttcta taaatgagct ttttgaaaga aataatagtt taaaagctca aaaaagtgaa
    12481 tattcagatt ccaaagatga aaatcctttt aatcagctta taaaaagtat agtagaagaa
    12541 aatacattaa aaagtgaatg gcaacttcgt aatatacttt ttgtggaatt taaagcaagt
    12601 atagattcta aaaaatgtaa aataaattat tttaatattc caacttattt agcaaaattt
    12661 tttacagaca agtatgcaaa taaaaaaata caaagtatct atgattacaa gcttaaatca
    12721 aatgtactag atttactctt gaaaaatagg gacttgaagc atctaactaa taacatttta
    12781 agaaataaag ttaaaaatga tatggaaagc aacaacaaat caaatatatc aggaatagat
    12841 tgttttagag tagtccaatt aagagcatta ataaatagct acaaaaaggg ggtatataaa
    12901 atggatagta aaaatttgga gaagaatgat gaaaagctga gaataattta ttatttaggt
    12961 tgtgatatac atgactattt tgttaataaa aattctaaaa ataaaataga tggagtaagc
    13021 tataaacttt taaattcagt taaagtcgga aataaaagtg attttatgga tacaattata
    13081 agagttttta tgtcagctga aaaacagatt ccagcattta ttttagatat agaaattgaa
    13141 aaagatttag actttgaatc tataggtcat gcttttatat ctggattaat ttctggaaaa
    13201 tatgaaggaa aagacaaact accaaacgaa aaggaggaaa aataagatga aaagagggtt
    13261 aacatttaca gtaatagcac aggctcaaag tttaaactat ggggaaggga taggtaatat
    13321 atcagaatta aaaaaattaa gtagagatga tggaaatata tatacatttg catctcgcca
    13381 gtgtttaaga tatgacatag tacgattagc agcagaattg tttaattgga atttacaggt
    13441 tgtcgataaa gaaaaaggta ctattcaatt taaagacaat ataagtataa gagaatcaga
    13501 agaaatggat ttatttggat atatgaaaac aaataaaaaa gatgagaaag ataaaaaagg
    13561 aggttctttg actagagaag ctactgtaag attaagtaat gcaatttccc ttgagccata
    13621 tagaagtgac atggactttt taaataataa aggattagca gatagaatag gagaacatcc
    13681 taatcttgct aacatagagc aacatttaag ttattataca tatacagtga ctatagattt
    13741 atctaaaata ggtaaggatg gagatataga acttgataat aaagagaaat gtagaagagt
    13801 agtagaattt ttagaaataa taaaagtatt gaatagaaat attagaggta gacaagaaaa
    13861 tttatctcct ctatttgtag taggaggagt atatgaaata gcaaatccat ttttcttggg
    13921 tagaattaaa ttaaaaggag ataaaaatgg atttaaaata aataagcaag ctatagaaga
    13981 agtaattcaa ggtacttttt taggaaaaga tttaaaagaa tttacctatg ttggaatggt
    14041 agatggggta tttataaata aagaagaatt taagggattg tttgaagata attttttaag
    14101 tgtagataaa ttttttggac aactagttaa agaagtaaag gaatattatg gggtgaatta
    14161 atatgaaggt tttgaaatta gatttatttc aagaaactgc atgctataaa aaaccatttg
    14221 ctatgaagat tacagagaca tatccactgc ctccatattc tacaataaat ggattaattc
    14281 acaaaatatt aaatgctaca gaatatatac catttaatat aagtgtacag ggaacatatg
    14341 aaagtatatt taataattac cagacaacat atttttataa aaaagatagt attacatcta
    14401 tgccaatgaa tagtcatatg ctattgaatg taaatttgat aattcatata ggtggggatt
    14461 ttgatttatt ggaagaaata tatgatagtt tattaaatta tgacgagcac ttatcattag
    14521 gtagaaaaga agatttagta agaattaatg atattagatt tgtagaagtc aataaatttg
    14581 aagtagatga ggatatacaa ttagatgatt atgaaaatta taagttatca gaatgtaata
    14641 taagaatgcc tatatatata ccaaaaacaa gtttacaaga tacagatata gatggtataa
    14701 gttacagact caataattac tatgataata atgctgtgga agataaaaaa agggtttgga
    14761 ataaggtaga tagttattat gttgaggatg gaaatactat atcaattgga gatatattat
    14821 tagataatga aggagattta ttatatttta ataatataaa ttaggaggga gagtatgtta
    14881 tatgctaaat ctaatccagt ggaaacactt agagaacata ctgatgaact tttaaaacaa
    14941 atgaatgtat taagagaaag ttatggaaaa aatataaata gcttagattt tctagaggaa
    15001 gagatatttt ggcaattact tgactttgtt atagaatttc atgatattgg aaaagcattt
    15061 tcaccgtttc aagagttaat aaaaagcaga atggatacta aaataaatga acctaaaata
    15121 gtaactcatt tagaaaataa tgtaggccat aattatcttt ctcctgcatt tattgattat
    15181 agttatatag acaggaaaaa aaataaagaa cttagagcag tattaaatca agttattgta
    15241 tatcatcatg aaagagatat ctttatagat aaagatttta aaaatttaat acaaaaaata
    15301 ttagatgaag atttaataaa taaagtttat gaactacagc gtgaatttaa agttagatat
    15361 ccaataaaaa cagaaaaatt gagtaaagta tatctacaaa gtgtagaaaa aagaatagat
    15421 aaaaatcaca agtactataa tttatatatt atgttaaaag gaatactaca tagactagac
    15481 catagtgctt ctgctcatga agttgtggaa tgcaataatg ttataaatat aggagaacag
    15541 acagaaaatt atttaatgaa agagtttggt agtttgagag aggctcaatc atttgctaaa
    15601 tctaatagaa ataagaatat aatactgatt gcatctacag gaatgggaaa aacagaaact
    15661 gctttgattt ggatagataa ggataaagca ttttttacac taccattaag agtaagtata
    15721 aatgcattat ttgatagggc taaaaatata attggagtag gagaagcaaa tgatacattc
    15781 ttaggtctgt tacattcaac agcaatagat tatttagaag aaagtaatca ggaaaattca
    15841 agtgagattg tagatttagc aaagttatta tcttgtaaac tgacattttc cacaatagac
    15901 caaatattta aatttccttt tttgtataga ggctatgaaa aagtgtactc aacattagca
    15961 tattcaaaag tagtaataga tgagatacaa gcatattcac cagaaatagc agctgtattg
    16021 gtaaaaggta tagaaatgat acataagata ggtggcagat ttatgataat gacagctact
    16081 atgccaacca tatatataga tgaattaaaa aaaagaggtg taatgaatag taacttagct
    16141 gacttgacat gtaacacaga aaaaataaga cattgtgtgt ctattgtaga aaattcaata
    16201 gatgaaaact taggtaaaat aatacaaagt ggaatgaata aaaaagttct tgtaatagta
    16261 aatacagtta aaagtgctgt agaaaaatat gagttaatag aagaaatagt taaaccaaaa
    16321 ggaatagatg tcaacttaaa tcttttacat tctatgtata tacaagaaga tagagcaaaa
    16381 ttagaaaaat atataaaaga atttgcagat agtgatagta atggtatttg gattactaca
    16441 caattagtgg aagcatccct tgatattgat tttgatgagc ttcatacaga aaattcaaca
    16501 cttgacagtc tatttcaacg atttggtaga tgttatagaa gtcgtgagta tgaagaaaat
    16561 agcccaaata tatttatata tacagaaaaa gctacaggaa taggtagtat ttatgataag
    16621 gatattgtag aaaaaggact tgagctactg aaaactttta taaatggaaa agaatgtgtg
    16681 aagatgaaag aaaaatataa ggtagaaatg gttaagatac tatactctaa agaaagtcta
    16741 gaaggtacag cttttgaaaa gagatttacc agtgctttaa atattttaga tactataacg
    16801 ccatatagtt taggttctaa agatgcacaa aatatactta gaaatattga aggatataca
    16861 gtaattccag aggatatata taataaaatt gaagaaactt taatcaaaga ttatgaagag
    16921 ttgggacaag agcttataaa tgcatatagt aatgatgata gacaattgat aaataaaata
    16981 aagtctaaga gaaaaaaagc aagaagagag ataattaaaa aaactgtaaa tttaccaata
    17041 tataaagcta aacaaaatgt aattgacata caggtgaaag gtcttgaaga tttaaaaata
    17101 cttttatata aatatgatat acacgaaaat aagcatacaa aacagatatt tggtaaaggt
    17161 gtgcttataa gtaatgaaat agaccaattt atttgatttt tatattaaca atgtggctaa
    17221 aatttactaa agaaggtgat tttgtgccaa tagatttaga agtattaaaa gttcaaggcg
    17281 taaaaataaa ttattattat gtatgtaaaa gaaaactatg gctattttct aaaggaataa
    17341 ctatggaaca aaatagtagt agagtattgt ctggaaagat agtacatgaa gattcatata
    17401 aaagaatgaa aaataaagaa atgttgattg atgatatctt gaagctagat ataataaagg
    17461 acgagtatgt aaaagaagta aaaataagtt caaagatgaa agaagcagat gaaatgcagt
    17521 tatactatta cttatactat ttaaagaata gtatgggtat agagaaaaaa ggaactataa
    17581 attatgttaa ggaaaagaaa caagaagaat tgatattgac agaagaaaaa gaaaaaatta
    17641 ttgaaaacac acttataaat ataaatgaaa taaatatgca gttatctcct cccaaaattg
    17701 agaaaaaaca ttattgtaca aaatgtgctt attatgaatt ttgttttgtg aaggaggagt
    17761 aacaatgtat aaagactatt atattataag taatggaaat ataaaaagga aagaaaatac
    17821 gatttactat tacaatttag aaggtgagaa aaaaatatta ccagtagaac aagttgatga
    17881 tattcatata tatggagaag tagatttaaa cacaaaactt ataaattaca taagtaaata
    17941 tggggtgatg cttcatttct acaattacta tggatattat tcaggtacat attatccaag
    18001 gaagaaaaat gtatcaggat tcagtttagt atgtcaatca gcctgctatt tagataaaaa
    18061 tgaaagatta tacttagcaa aatcctttgt ggaaagtgca tcataccata ttttaagaaa
    18121 tatgagatat tacaaagttg atgaaagttt aattgatact ataaaggatg aactaaatga
    18181 tttgaatgat gtcaaagaaa tatcagaact tatgggtaaa gaaggcagaa taagaaaaac
    18241 atactataaa tcatttaatc aaatattaaa agatgatttt gaattttata aaagagaaaa
    18301 aagacctccc aaagacccag taaatactct tatgtctttt ggaaatagca taatgtatac
    18361 gaatgtttta agtgagatat ataagacaca acttgaccct acaataagct ttttacatga
    18421 accatcaaca aagagatttt ctttaagttt agatattgca gaaattttta agccaattat
    18481 agttgacaca ataattttta gcctgattaa taataaaaga attaataaga atgattttga
    18541 atatcaagac aaaatttgtt atttaagtga aaaaggaaag aagaaatttt tgcaagaatt
    18601 tgaaaataag atgcagacaa ctataaaaca tagaaatcta aatagaaaag tttcatatag
    18661 aatgtttata aggttagagt gttataaatt aattaaacat tttataaatg atgaaaggta
    18721 caaagtttta aaggtgtggt ggtaagtatg tttgttattg ttacttatga tattgttgaa
    18781 gcaaggtcgt taaatagaat tagaaggata cttagaaaat atttgacttg gacgcaaaat
    18841 tctgtttttg aaggcaatat tactgatgga aagttacata aatgtatttc tgaaatagaa
    18901 aatattattg ataatagcga ggattcaatc tatgtttatg agataaaaaa tcctaattca
    18961 attaaaaaga aatgttatgg gattgataag tattctgatg aaatgtttat ataggtttgc
    19021 agtgagcgat atttatgcta aaataggtgt taacagttgg aatataaggg attgaaggtg
    19081 tatgataact gttatcaatt gcactactgc tcgctcactg caaattttga tgtttttatt
    19141 gaattataat tgcttgattg aagtattttc aatgtattca attataccta ttttggggtt
    19201 ttatattaac taagtggtat gtaaataagc aactatagta gaagcaaaag cgacaacaac
    19261 taaaggtttt atattaacta agtggtatgt aaatttggtt aacttaagtg ctatgaaagg
    19321 aattaatgaa gttttatatt aactaagtgg tatgtaaatt taaaggtgca agtcttaata
    19381 cttgttacat gagttgtttt atattaacta agtggtatgt aaataacaaa gaaccatttg
    19441 aatcacgaaa actaaaaaac agttttatat taactaagtg gtatgtaaat ttattaacct
    19501 tatcagaaac ctgaccatcc caattatagt tttatattaa ctaagtggta tgtaaattcc
    19561 atttgtctaa tgcttctaac tcttttttta tacgttttat attaactaag tggtatgtaa
    19621 attccaaaat gggcttggag ttaagagttg tataagaaac gttttatatt aactaagtgg
    19681 tatgtaaatt aattacacac tcccttttaa cgaacatatt ttagattgtt ttatattaac
    19741 taagtggtat gtaaatagac tcgacataga atcggttact aaatccgagg gtttcaggtt
    19801 ttatattaac taagtggtat gtaaatacta aacctttttg tttactttta tttctcattt
    19861 tacgttttat attaactaag tggtatgtaa atccggattt ttctgcttcg actgttgtta
    19921 ttgagacttg ttttatatta actaagtggt atgtaaatag taattccatg caatctttta
    19981 tattgctttt taacctgttt tatattaact aagtggtatg taaatagata tacaaggtga
    20041 aagtgttgaa atttcaatct tgttttatat taactaagtg gtatgtaaat attcttagat
    20101 gttataattt gtgttgcatt taaatcgttt tatattaact aagtggtatg taaatacaat
    20161 attattgttc atttcattta ataattctag tagttttata ttaactaagt ggtatgtaaa
    20221 tttgtttata cctttaatct ttaaaattaa atataaaagt tttatattaa ctaagtggta
    20281 tgtaaatcat tgtatactaa gcttgatata gtgcaaaatg aaacgtttta tattaactaa
    20341 gtggtatgta aatactaatt gggttaaaca aatggatata actaaattag ttttatatta
    20401 actaagtggt atgtaaatcc aacccttcgc acgaatccgt gcgacgaaat ataaagtttt
    20461 atattaacta agtggtatgt aaattgtaaa aatattgctt agcatattga tatcactaac
    20521 tgttttatat taactaagtg gtatgtaaat acaagaggtt tttcagcaat atatgtactt
    20581 ctataatgtt ttatattaac taagtggtat gtaaattcat caatattaat tttgggaata
    20641 tcaacatttt ttgcgtttta tattaactaa gtggtatgta aatgcgataa gagattcgag
    20701 tctttttact gggcttaatc gttttatatt aactaagtgg tatgtaaata ggataaagaa
    20761 aagactcaca caagacacag tgtcaggttt tatatcaact aagtggtaga taagtagaat
    20821 attagcaata tcaacgagta tttagaaact tattttatat taataaagca gtatataaaa
    20881 ttgtagaata aacaatagca tatactaaaa catccacctt atattaacta aatcatatct
    20941 aaataaaatg cacttaccta taaacattat aaaatcaata caaaaatgag gtgaaacaaa
    21001 atttatgata aagaaattaa acaataaaga cataaataaa atcatggaaa tatgggaaaa
    21061 aagtacaatc aaagcacatg actttataag taaagaatac tggcaaaata actacaatac
    21121 tgttaaaaac gaatatatac ctatatcaga tacatttgta tatgatgatg gagatgaaat
    21181 aaaaggattt ataagcataa tagataaaag ctttatagga gctttattta tagaacccaa
    21241 ataccaaaat ctaggtatcg gaggtaaact tttagattat gcaactaaaa aatataaaag
    21301 tctaagttta gcagtatata aagataataa aaaagcagtt gtgttttata ataaaaaagg
    21361 ttttaatata gtaaaagaac aagtaaatga agattcagga tttaaagagt acataatgga
    21421 atatagtaaa taatatgatt acattctatt aaaagaataa ttaatttatt ttctatttga
    21481 tttttataag agtaattttt aaaatagact atatgaagat aaagatattt attatagatg
    21541 taagttaatc agaattgata tagctacaaa agaggaaaat aaaattgtat ggtgtatttc
    21601 agatttaaca aatttactat ttaaagataa taagtttgat ataatattaa agatactttc
    21661 acctataaac tatagggtat ttgaaagaat tttgaataat tatggaatgc taataaaggt
    21721 ttgttaaaat ttaataatta ttagattata gaaaattgcc atgaaattag ttcagcaaga
    21781 actagtttca tagcaatttt aattcttata agtgtattta tttttacaga tttaaaaaac
    21841 ttatacagta tctaataatg taatcttatt actttagcct ataaatattt aaatcttaaa
    21901 atgttctctt tgagataagt ttatttcaga gtcacaattt ccacaacagt aagatgttga
    21961 gacatcttta aatttttcag tattctcatc aaagttcatt tttttctttg caataattcc
    22021 taccttagtt aaattagaac cacaattatt acagttttga attttacata ggttatatag
    22081 tttattaagt gtaatatctt ctaataattc atcacaatta caacatctga tagaagaaac
    22141 ttcactagac atttcaatag gttcagcttc tttagaagaa aatttatatg ttatgtcatt
    22201 tgatacttta taacctgtat caaatatatt agaattacaa cttggacata agtactttgg
    22261 aagatatata tctttttttt caaaagtatc actactaata ttacagttta attcatctaa
    22321 aattggtctt tcatctaggt tattaccttt atttaagctt agaagataat tataaatttt
    22381 tttatcttca ttctgttttg atgtatctaa caaatgctcc attatattag tgtatttttt
    22441 gttttttgaa ggcatgttta aatccagata attgttttca atagcaaagc atactatatt
    22501 gaaatagtta tatttaactg caaaaaataa taacatttca tcaaatactt tatctattat
    22561 tttgtcagaa atacttatcc aaaaatctgg tgactctaag taaactttcc tactaagttc
    22621 atctaactct tcatctatat tatttatatt attttcatta actttcatat catcacttcc
    22681 ttttaaatat cttgtgtata aactatttgt tactattttt tatataaaat aaaatcttat
    22741 ataaaaatat atcatattat aatttacaag tatagtctaa atagagctgt ttttaagcaa
    22801 agttttataa atgactatta aaatataaag taacagtata aagtttactt ataaattaaa
    22861 cgtaaaccta aatacttgta atggttgaca aaaaaacgtc tttattttat actaaaacaa
    22921 agctttaata gaggctttgt atatgtacat ataaactaaa tgaaataaga catatgaagg
    22981 gaattataaa aatgaaaaat actaaagtaa atattcaaga tttaactaaa atgtcaatat
    23041 gtgtagcatt attgtgtata tcatcttaca tatatatacc attgccattt actccagcag
    23101 gagtaacagc acaaacaata atgataaatt tgatagcttt gattttaaca ccaagacaag
    23161 catttagtac agttggtgta tatataatga taggtttaat tgggattcca gtatttggtg
    23221 gaggtacatc tggtattgga aagttgttaa gcccaacagg tggtttttat tttgggtttt
    23281 tgtttgcagc actaattatt agtttattaa aaggacgaaa taatgatatt aagagatata
    23341 tactaataac aatttttgtt ggaatgccta ttatatattt tatgggaaca gtatttatgt
    23401 gctattttaa tcaaatgaca gtagaagcag cactttttgc agcagtagta ccatttttaa
    23461 ttggagatac aataaagtcg gttattgcat cttttttagg cactaaactg aacaatgtac
    23521 tcagaagaaa tctatgataa atctataata taaggaaggg tgtaatgtat gaaggaagtt
    23581 tttatattag gaggattgag aagtcatata ggtctaaaaa atggaatttt tcaatttgtt
    23641 caacctgaat tactaggagc aagtgtttta aaagatttaa ttaaaaagta tgaaattgac
    23701 aaaattgatg agattatatg tggaaatgca gttgggacag gagggaatat agccagatta
    23761 atgactttaa cagcaggagt gtcaaatgaa gtacctgctt ttactgtgga tatgcagtgt
    23821 gcttctgcta tgatgagtat agacatagct ttttcaaagg ttaaatctgg tcagtgtaat
    23881 ttaattattg caggtggttt tgaaagtagt tctctacaac caatgcgcac atatcataag
    23941 aatgataagc gatataatac aaataatcca aattatacag ttgctcaatt ttctcctgat
    24001 gataatagtc aaaatagtat gctcgaaggg gcggaaagag tagcagagtt atatcaaatt
    24061 gagagagcag acttggattt ttgggtaaag gaaagtcata aaagagcaaa agaagcaaga
    24121 gaagaaaaaa tacttgagga tattatatct cctataaata atagtaccta tgatgaaggt
    24181 atacgtgata agatgagtca aaggttatta gataggatgc caccaatttt aggaaaagaa
    24241 actattacaa atgcagcaaa ttcatgtctt attaatgatg gagcttcatt tattataata
    24301 tgttctaaga agtatttaga acatgtaaaa aagaagccta aaacaaaaat tattaataca
    24361 tgcacaatag gaacagatgc aaccttaagt ccaacatcag cgatacaagc aatggataaa
    24421 cttttagaga tagaaagcct taattattta gatgtatctg ctgttgaatt taatgaagca
    24481 tttgcagtta tagatgtgtt gtttcaaaga aagtatccag agttaataga gagatataat
    24541 atatttggtg gagctttagc gtatggacat ccatatggtg cttcaggtgc aattattaca
    24601 ttacatcttt taaaagcatt agaaaaaact aagggtagat atggaatttg ctctatagct
    24661 gcagctggtg gtctaggttc agctttactg cttgaaaggg tgtagattat gaactattat
    24721 gaacttttaa gaataaaaaa agagaggcat aaaaataaaa attttttaat tatagatgga
    24781 gaaaaatata cttatgaaaa tatattaagt tatagtgagc aactaggaaa acaaatttct
    24841 ttaggtgaaa atatctcaat tttaatatat tctaaaaata taatgtttca gttgattagt
    24901 ttttttgcta ttaattattc aaaaaatatt cctattattt gtcattataa tctttctaaa
    24961 aaagtattag atgatatttt attaaaaaat aatatttcaa tcattatatc tgatgaatct
    25021 atggacgtta ttgatttata tgatgataac aataatgaag tagcaaaaaa agttaatttt
    25081 tctattttta atcctaaatt taatctatat atgtatcaat ataagaacct tataaattat
    25141 ttagataaaa gtatttgtat gggagcttta tcttcaggtt ctacaagtgt tccaaaggta
    25201 ttatatagaa catatgagag ttgggctgga ttttttccta tacaaaatgg tatttttaat
    25261 atctctgggg aatcaatctt gtttgttaat ggaacactta gttttacagg gaatctaaat
    25321 tctataatgt cagtattata tgaaggaggt agtattgtaa taagttcagg tcttaattgt
    25381 aaatcatgga taaggacaat aaaacaatat aatgtaacta acatatacct tatacctaca
    25441 aaacttcaac ttttggttaa acacttaaaa gaaccagtac tcaaagtagt aagtattttt
    25501 acagggtctc aattattatt tgaatatact gcaagaaatc taaaaaaata tatgccaaag
    25561 tctgaaatta ttttatacta tggggcaagt gaattaaatt atattacata tttatgctat
    25621 gatgaactaa ttgaaaaacc tctaagtgta ggcagaccat ttccaggaat agatatatat
    25681 attagaggag gaaaaatttt tgtgaataca gaatatgcag tatataatgc aaccaaacct
    25741 tattctgtca atgatattgg atattatgat aatgatggat acttaatatt tgaaggaaga
    25801 agtgatgaca ttgtaaatat tggaggattt aaagttagtt ctgctaagat tgaaaatgaa
    25861 gttaaaaaaa ttcctcaaat tgaagatgca attgtattgc cgtactcaga cactataaga
    25921 ggaaatcaaa ttgtattatt tgtaataact atagacaaaa ttacgaagaa agatttgttg
    25981 attaaaatga aagataatct aatgaaaaat gaaatcccaa agaaaattat ctttttaaat
    26041 tcatttccat atacctcttc tgaaaagata gatagattag cattattaaa aatgttataa
    26101 gtataatatt tagtaatttt agtgaaccaa tgtattgata aaaacatatt gtatatagta
    26161 aaggaggctt acaatatgtc aaatcaatac gatataactg ttattggggg agacctgcga
    26221 caagtgtaca tggtaaaaaa actaattaat aaagggtatt ctgtagtcac ttatgggata
    26281 tcaaatgaaa ttataaatgg aatcgttgga aaatcaactt cactagctga agcactatcc
    26341 aaaagttcca ttattttatg tccaattcca tttacaaaga atcaagttaa tattgaaaat
    26401 acggatgatt gtcttgatgc tactattgat aacttgctaa ttaatttatc tcctaatcaa
    26461 atattatttg gaggtaacat accaactaaa gtttgtaaat tttgcgagca acactctatt
    26521 cagatttatg attttatgaa aatgaatgat gttgctattt taaatgcagt tgctacagct
    26581 gaaggggcta tagcagaagc tattaaaaga agtataatca atatacatca aagtaactgt
    26641 ttagtattag gttatggaag atgtgcacaa atacttgcaa aaaaattata cgctttggat
    26701 gcaaatgtat gcgttggtgc aagaaataat gatgcaagaa gtacggctaa tgcatttgga
    26761 tattccagta tttctttaag tcaacttgat gaaaaacttt tacaatttga ttatattttt
    26821 aacaccatac cagagtgtat tttaacgaaa gaaagattag aaaaagtatc acaagaagta
    26881 actattatag atatagcttc ttctcctgga ggagtagatt attctgttgt taaagaagta
    26941 gggattaatg cgactctttg ccttgggctt cctggtaaat attcaccaaa gacatctggt
    27001 gagattcttg ttaacgctat agaaaatatt ataaatgaaa gaagggatta gaaatgagac
    27061 ttgaaggact tacaattgga gtaggattta ctggttcgtt ttgtacttat gataaaatat
    27121 ttatagagtt agagaatttg gttaaagaag gagctaatgt acacactata ttttcagatg
    27181 tatcacaaaa tatcgattgt agatttggaa attctgaaga gtttatgaaa aaagcatatg
    27241 aacttacagg aaataaacct atagttacga ttgaagaggc agaaccattt ggacctaaag
    27301 ggattgctga tattataata atagctcctt gtactggaaa tactgctgca aaattagcaa
    27361 atggtattac agattcacca gtattaatgg cagcaaaagg tcatcttcgt aatgataaac
    27421 cactagtaat atcaatatca acgaatgatg ctctaagctt taatttcaaa aatattggta
    27481 ttctccttaa ttctaaaaat atatattttg taccttttgg tcaagataat tgcaaagcaa
    27541 agcctaattc tatgattgca catactgagc taataattcc aactatagaa cttgctctag
    27601 agaacaaaca gctacagcct gttataaaaa gtccacatca atagaattgg ttcttataat
    27661 attatgtatt agatacaata ctagcaaaga ggctgtctca aaatagagag aagcctcttt
    27721 ttcattgttg aaatgatgaa aatatattta atttcataca aaaaaatgca tcatgaacta
    27781 aaaagtctat tttgagctaa tctccgtaat ttttggtata ttaaaattat ttacttaatc
    27841 caatttttaa attagaattt atatcgtttt gactcttcaa atatcaatct aactgttgtt
    27901 gatacaaaag aagaggacat aattaaaaca aatactgata gtcctctaat aaacaaatta
    27961 tctacataat aagttactat tccaatacct ccaatcgtta aaattacact tataatcaaa
    28021 gaaaaaatgc taattgtttt taattttttc atgcttatcc tccttcttat aaacttcaaa
    28081 tttatctata taatattaaa tatattttat ttcatagtat ataaaaatca tgaatatat
//
LOCUS       DAMJWO010000054        28051 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.055, whole genome shotgun sequence.
ACCESSION   DAMJWO010000054 DAMJWO010000000
VERSION     DAMJWO010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28051
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.055"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(43..1683)
                     /gene="bclA2"
                     /locus_tag="PC366_002383"
     CDS             complement(43..1683)
                     /gene="bclA2"
                     /locus_tag="PC366_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HDF2577890.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGATGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGANGTTGSTGPTGNTGATGANGITGPTGATGATGA
                     NGITGPTGNKGATGANGITGPTGATGATGANGITGPTGNTGATGANGATGLTGATGAT
                     GANGITGPTGATGATGANGVTGATGPTGNTGATGPTGSIGATGANGVTGATGPIGATG
                     PTGAVGATGPDGLVGPTGPTGPTGATGANGLVGPTGPTGATGANGLVGPTGATGATGV
                     AGAIGPTGAVGATGPTGADGAVGPTGATGATGANGATGPTGAVGATGANGVAGPIGPT
                     GPTGANGVAGATGATGATGANGATGPTGAVGATGANGVAGPIGPTGPTGANGTTGATG
                     ATGATGANGATGPTGATGATGVLAANNAQFTVSSSSLGNNTLVTFNSSFINGTNITFP
                     TSSTINLAVGGIYNVSFGIRAILSLAGFMSITTNFNGVAQNNFIAKAVNTLTSSDVSV
                     SLSFLVDARAAAVTLSFTFGSGTTGTSPAGYVSVYRIQ"
     gene            complement(2061..2600)
                     /gene="hpt"
                     /locus_tag="PC366_002384"
     CDS             complement(2061..2600)
                     /gene="hpt"
                     /locus_tag="PC366_002384"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDF2577891.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGKVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            complement(2928..4235)
                     /locus_tag="PC366_002385"
     CDS             complement(2928..4235)
                     /locus_tag="PC366_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HDF2577892.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDAAEKAESLMDTVTIQELIKNVEEIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDEKLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            complement(4660..6435)
                     /locus_tag="PC366_002386"
     CDS             complement(4660..6435)
                     /locus_tag="PC366_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2577893.1"
                     /translation="MMVMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDVCRECYKSGACVEFAEVCCPIICD
                     GDSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLEKMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            complement(6432..6569)
                     /locus_tag="PC366_002387"
     CDS             complement(6432..6569)
                     /locus_tag="PC366_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577894.1"
                     /translation="MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNK
                     E"
     gene            complement(6647..7216)
                     /locus_tag="PC366_002388"
     CDS             complement(6647..7216)
                     /locus_tag="PC366_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2577895.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            complement(7400..8035)
                     /locus_tag="PC366_002389"
     CDS             complement(7400..8035)
                     /locus_tag="PC366_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2577896.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
     gene            complement(8703..9584)
                     /locus_tag="PC366_002390"
     CDS             complement(8703..9584)
                     /locus_tag="PC366_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HDF2577897.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGVKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
     gene            complement(9704..10711)
                     /locus_tag="PC366_002391"
     CDS             complement(9704..10711)
                     /locus_tag="PC366_002391"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HDF2577898.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            complement(10731..11213)
                     /locus_tag="PC366_002392"
     CDS             complement(10731..11213)
                     /locus_tag="PC366_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HDF2577899.1"
                     /translation="MSFVGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSE
                     HNEWKTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPAVGLTIM
                     GADGLVITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKALAFLKLKMRKDAK
                     "
     gene            complement(11231..11698)
                     /locus_tag="PC366_002393"
     CDS             complement(11231..11698)
                     /locus_tag="PC366_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HDF2577900.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            complement(11713..12471)
                     /gene="prdD"
                     /locus_tag="PC366_002394"
     CDS             complement(11713..12471)
                     /gene="prdD"
                     /locus_tag="PC366_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HDF2577901.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            complement(12551..13276)
                     /gene="prdB"
                     /locus_tag="PC366_002395"
     CDS             complement(12551..13276)
                     /gene="prdB"
                     /locus_tag="PC366_002395"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(12824..12826),aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HDF2577902.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            complement(13314..13598)
                     /locus_tag="PC366_002396"
     CDS             complement(13314..13598)
                     /locus_tag="PC366_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577903.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            complement(13679..15559)
                     /gene="prdA"
                     /locus_tag="PC366_002397"
     CDS             complement(13679..15559)
                     /gene="prdA"
                     /locus_tag="PC366_002397"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HDF2577904.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            complement(15988..17748)
                     /gene="prdR"
                     /locus_tag="PC366_002398"
     CDS             complement(15988..17748)
                     /gene="prdR"
                     /locus_tag="PC366_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HDF2577905.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
     gene            complement(18218..18380)
                     /locus_tag="PC366_002399"
                     /pseudo
     CDS             complement(18218..18380)
                     /locus_tag="PC366_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011020315.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(18549..19862)
                     /gene="prdC"
                     /locus_tag="PC366_002400"
     CDS             complement(18549..19862)
                     /gene="prdC"
                     /locus_tag="PC366_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HDF2577906.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     gene            complement(20251..21015)
                     /locus_tag="PC366_002401"
     CDS             complement(20251..21015)
                     /locus_tag="PC366_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2577907.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKYDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKKTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            21306..21509
                     /locus_tag="PC366_002402"
     CDS             21306..21509
                     /locus_tag="PC366_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HDF2577908.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            21699..22235
                     /locus_tag="PC366_002403"
     CDS             21699..22235
                     /locus_tag="PC366_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HDF2577909.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(22239..23105)
                     /locus_tag="PC366_002404"
     CDS             complement(22239..23105)
                     /locus_tag="PC366_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HDF2577910.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            23253..23498
                     /locus_tag="PC366_002405"
     CDS             23253..23498
                     /locus_tag="PC366_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HDF2577911.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            complement(23612..24910)
                     /locus_tag="PC366_002406"
     CDS             complement(23612..24910)
                     /locus_tag="PC366_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HDF2577912.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKETYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLPHFNKVITTTPNNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(25043..26074)
                     /locus_tag="PC366_002407"
     CDS             complement(25043..26074)
                     /locus_tag="PC366_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HDF2577913.1"
                     /translation="MENICDMNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYI
                     FISDKFDDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNI
                     RLINLSLSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFT
                     LDGDDSFWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEK
                     PGITISDLNDKLESLATRNHWDSCDFDECSRIVNFKLDLYDKENALLMKVADVVRDCL
                     DIEDNNEKLFKGSLFNKEIGLVYDNCFNLLKKLEHRFDIKFNYMDISKYDLVSIYTLT
                     ELVERYKNL"
     gene            complement(27120..27830)
                     /gene="rgaR"
                     /locus_tag="PC366_002408"
     CDS             complement(27120..27830)
                     /gene="rgaR"
                     /locus_tag="PC366_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HDF2577914.1"
                     /translation="MFRVVICDDEKIQRSILKEFTKKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNMITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
BASE COUNT         8557 a         5210 c         3121 g        11163 t
ORIGIN      
        1 aatcatattg tttattattt tataatcttt tcatcatata aactattgta ttctataaac
       61 tgatacatac ccagctggag aagtacctgt cgtgcctgaa ccaaatgtaa agcttaaagt
      121 aacagctgct gctctagcat caactaaaaa gcttaaactt acacttacat ctgatgaagt
      181 aagcgtattt actgcttttg caataaagtt attttgggct actccattaa agttagtagt
      241 aattgacata aatcctgcaa gtgaaagtat ggcacgtata ccgaaagata cattgtatat
      301 ccctccaact gcaagattta tagtactact tgttggaaaa gttatattag ttccatttat
      361 aaatgatgaa ttaaatgtca ctaatgtatt attccctaaa cttgaagaag atactgtaaa
      421 ttgtgcattg tttgctgcta acactcctgt tgctccggtc gctcctgttg gacctgttgc
      481 tccatttgct cccgttgctc cggtcgcccc tgttgctccg gtcgttccat ttgctcctgt
      541 tggtcctgtt ggacctattg gacctgctac tccatttgct cccgttgctc ctactgctcc
      601 tgttgggcct gttgctccat ttgcccctgt tgctccggtc gctcctgttg ctcctgctac
      661 tccatttgct ccggttggac ctgttggacc tattggacct gctactccat tcgctccagt
      721 tgctcctact gctcccgttg ggcctgttgc tccatttgcc cctgttgctc cggttgctcc
      781 ggttggacct actgctccat ctgctcccgt tgggcctgtc gctcctactg ctccggttgg
      841 acctattgcc ccagctactc ctgttgctcc ggtcgctcct gttggaccta ccaaaccatt
      901 tgctccggtt gctccggttg ggcctgttgg acctaccaaa ccatttgctc cggttgctcc
      961 ggttgggcct gttgggcctg ttggacctac caaaccatct ggacctgttg ctcctactgc
     1021 tccggttgga cctgttgctc ctattggacc tgtggcacct gttactccat ttgctcccgt
     1081 tgctcctata cttccggttg gacctgttgc tcctgtattt cctgttgggc ctgtagcacc
     1141 tgttactcca tttgctcccg ttgctcctgt tgctcctgtt ggacctgtta tcccattcgc
     1201 tcccgttgcc ccagttgctc cggttagtcc ggttgcacca tttgctcccg ttgctcctgt
     1261 atttcctgtt ggacctgtta ttccatttgc tcccgttgct cctgttgctc ctgttggacc
     1321 tgttatccca ttcgctcccg ttgctccctt gtttccggtt ggacctgtta ttccatttgc
     1381 tcccgttgct cctgttgctc ctgttggacc tgttattcca tttgctccag tcgctcctgt
     1441 atttcctgtt ggtcctgtag aacctgttgt tccatttgct ccagtcgctc ccatatttcc
     1501 tgttggtcct gttattccat tcgccccggt tgctcccgta tttcctgttg gtcctgttat
     1561 tccatttgct ccggtcgctc cggttgcgcc tctaggcccc gtcggtcctg ttggaccagt
     1621 agcacctgtt ggccctgttg gacctacatc ttgatataaa cttggacctg aaatatcact
     1681 catataatta atcctccttt tttaaagtta gagtattact ctataaatat tgagtattac
     1741 tctatataat tatatgaatc gacaatttct tatgtgataa tgtatctatt tgcttatatc
     1801 aacatatatg ctttgattct taaatttcat tacttttttg taaaatcttt tacaattatt
     1861 agtactcttt tacaattatt aatacaatta aaaaactcat ttcccatcaa ttatttaaaa
     1921 tttttttatt atgttataaa aaatagataa ttaaattgca taaaattaat ttaatactac
     1981 tttaattact ttttaaataa aaaaacctca acacgattaa taaaaatcat attaaggcat
     2041 ccacaaaatt atataattgc ttatctatct tcatcagtaa cattgaatat ataaggaaca
     2101 tttctataat aatcaccaaa atcaaaccca tatccaacca caaacttatc ttctatttca
     2161 aatccacaat aatctggcac taaatcaact tttcttctgc ttggtttatc caaaagaaca
     2221 cagcatttta aactagcagg atttttagct tttagatgtt ttaacacaaa atccatagta
     2281 agtgcagaat cagtaatatc gtctacaacc aaaacatcat atcctgctat atcagtagtc
     2341 acatctgaaa ccactttaac ctttccagta ctttcttcat tgtttccata actagatgta
     2401 gtcataaaat taactctaag tggtaaattt atatttctaa ctaagtctgc acaaaatata
     2461 aagctacctt ttaatagaga aactaccata agatttttat ctttataatc tttttctata
     2521 attgctccta attcccttaa tttatcttta attttttctt ctgaatacaa tacttcccat
     2581 ttttttgttt ctatatccat aaaaagacct ccaattgtaa taatccttct taattttata
     2641 agagattgct cactttttca atactcttat tcaatattag tcaatattat tgagttttta
     2701 tgttcattca acaattatta acaatgtatc ttatatttta agtagttcat atatccacac
     2761 taaattacat actatatatt ttagacaaaa aaagaaaaaa cttgcactaa caagtttttt
     2821 ctattataca taaatttata cataatcata ttttattaga gggtactaat taaatttatt
     2881 tatgctattt ttgttatacc tcataataca aaacatatta taaagtacta gtcaacttta
     2941 ttcatatcat tcattacatt taagattatc tcatctgtta tagacatacc tttgtcactt
     3001 actctaccta agttttgtat actttgctca acacttgaac caactatacc atttagtggt
     3061 ggtacaaaac aatcttgctt agctattata gcactttgta tagctgcaga tgctgcagaa
     3121 gataatttta atgcacaacc agctttcgca ccgtcacata tcattccact taagtcagct
     3181 atcatatttt ctatagctcc ttctatttgc ttttcagtac cattcataag ccaagagata
     3241 ccagcagttg ctccagtaga agcagcaaca ccacatccac acacagcaga taatcttcct
     3301 gtatagttct taatataacc agttactaga tgagatatag ctaaagcctt tgctagtttt
     3361 tcatcagatt gtgggaattt tttattataa gcaacgattg gaagaattgc tgttaatcca
     3421 tgatttccac ttccatttga actcataaca ggcattttta cgcctgccat tcttgcatct
     3481 gaagctccag cagttaacat cattgcataa tttataacat cattacctaa aagaccttct
     3541 tctatagact ttttaattcc atatccgaca ccaataccag ttttttgttt taatccatat
     3601 tcagccatct cttcattcat ttttactcca tctagtaaaa attctatatc tttaaaatca
     3661 atttcttcta cattttttat taattcttgt atagttactg tatccattaa actttcagct
     3721 ttttctgccg catcatttga agctgatact tttggttcat tgtctaataa tacttctcca
     3781 tctttttcta agaacgtaaa attatcatgt ttagttctta ttctcacttt agcaatatga
     3841 ttttttcctt ttaacacaac ttctataaat actttctctc ttgtatcagc aggtgttatt
     3901 gatagtggag tattatccat ataatcctca gctattttaa cttcttcttt tgttagagtt
     3961 tctaacacac ttaatccatt ttcagaatgg ccacctacta tacctagagc tgctgcaatt
     4021 tttaatccta atctttcagt acctggtata cctacgcaca tgccattttt gtagatacta
     4081 ggactaacta acatacgatt ttcaactatt tcttctccta ataattcctt tgcctttgca
     4141 catgctagag ctaaggctac tggttcagta caccctactg ctggtttaac ttctgccttt
     4201 aacatttcca ctaattcttt tcttatatct ctcattatat ataaacctcc caattaagtt
     4261 tagatttagt actcaaataa ttaattaaat aatttcttat ctatatttat agcaaaatac
     4321 atgccatatt ttttatatct ttttatattt ttagtcttat attctataac cattggtatg
     4381 actgcttcta tttatgtatt ttttttattt acatagagta tttatattct ttaaaatgga
     4441 gaaacatatg acaatttcgc aaaaagacaa aaaaaagtct cagaatgaga ttctatatca
     4501 ttttgagacg gctcaaatgt gttatttttt aacttataaa aaccattttt taattcataa
     4561 aaaaagatta tgcaaaacac ttatagtata agtttaaagc tttctttaaa gttatgaatt
     4621 tagaaaaatt taaattttat atagcttttt attatattac tatgaaatta tattgtattt
     4681 ttcaattttt ctatataatg tagctcttga tattccaagt gctttagctg ttaattcttt
     4741 atctttttta taatctttgt acttatttaa agcttttatt atctcaatct tctctagttc
     4801 atcaagtgga attatcctat cgcttttaac ttctaactct tctacagagg tattcttaat
     4861 tttttgagga attacattca ttgtgattat tgaagaagaa gacatattca cactatattc
     4921 aataatattc tgcaactctc ttatattccc tggccactta tattccatca tagcatcaac
     4981 aaccctgcta tctatgtcaa taacattttt atctaatttt tttgaatact ctttaaccat
     5041 atgcttgatt ataagtggga tatcttcttt tctctctctt aaacttggta attttatagg
     5101 tataacattt aatctataat ataaatcttc tctaaaagtg ccattttgaa ccattttttc
     5161 taaatcttta tttgtagcag caataattct tacatctatt gagacatttg atttacttcc
     5221 aattttatta agttcctttt cttgtaatac tctcaataac tttgactgta aatgcaaact
     5281 catatctcct atttcatcta aaaatatact tcccttatga gctacttcaa acattccaag
     5341 ctttccacct tttttagctc cagtaaaagc tccctcttca tatccaaata attcactctc
     5401 taataaattg tctggtatag cagcacagtt tacagctata aaaggattat ctactctatt
     5461 gctatggttg tgtatggctc ttgcaaatag ctccttaccc gttccacttt ccccagtaat
     5521 aagtactgtt gatgttgatt tagaagctat tagggcttcc tttttagaat ttcttatagc
     5581 tacactttct ccaattatgt tttccaattt tattctataa tctttattca tcttattgta
     5641 gttttttata gcatctcttt tatctataaa atcaataaca tatcccttta actcattttt
     5701 taatactatt ttattgatgt tgtatattcc cttcgaatca tatccgtatc ttttataaaa
     5761 aaaactacac gatttgtctt tcttaaagtt atttatagaa ggtttcttta taaaatctaa
     5821 ttcgacaaat atgtttttgc cagttatact atcctttata ttgaaaagct ctttaaattt
     5881 tgaattatat ttatcaattt ttccatccac atcaatagac acaacagctt tgtccatatt
     5941 gtttaatagt gtctctaatt ttttcttttc taattcaagc tcataagttt taatttgtgc
     6001 ttttaattta ttagatatta agtctgccat tttgcctaaa aagtttataa gaccactttt
     6061 attattttct ataatttgtg cttgttcttt tgtaaaggct ataaggccta taacgccatg
     6121 agaatcgcca tcacatataa taggacaaca cacctctgca aactctacac aagccccact
     6181 tttatagcat tccctacata catcactact ctttgggtca tcaattagta ttgtgatctg
     6241 ttctgtaagt gattttttaa aagccgtata tttatctact ttctcaccta ttttgtctat
     6301 atatactcct gtacctgcaa tcctaaataa ctccttattt actatagtta catctatatt
     6361 gagtactgat actatagctt cagctatatt ttgaatatca gattttatat attctaaacc
     6421 tatcataacc atcattcctt atttttcttt aacataagta tttgtcttat ttctttaaga
     6481 atcaagtata tcttatttaa agtaaattgg attgacatca ggattacaaa gagcataaca
     6541 attattatta actcataatt tatttccatc taaacatctc cttataacaa aagactaggc
     6601 ttaacctagt cttttatatt atatccatat ttatatttta actcatttat cttctttttc
     6661 ccacataaat atattttaat ttatttgact ctttaatcat accatcaaag tttaatcttg
     6721 aaaatatatt aaatacttca tgtggatagt gaatctttgc aacagaacca caaaatttat
     6781 gtttaagata atttaactta acttttaaat tctttaaatt taaatcctct aatataacct
     6841 ctccattgcc ctttaacact ctttgtattt cagatgaagc tttttcacaa tctgtaataa
     6901 cattaaattg gtcaactatt attatcttgt tgaactgatt atcatcaaat ggtagaaact
     6961 ctaacttacc tttaactaca ttgcaatttt cattatacac tagagaataa cagacatctt
     7021 cataattact attctccagt atagttacag aagttccaag acctctcaat ctcttgccta
     7081 ggtttcctat atgaccaaca agcaatattt tatcacctac attatactca attgtatcca
     7141 aaaaacattc taattcatca gatgtatatt tagctttaac tggctgttta tttatctgac
     7201 ataatatgct tttcacaatg cttcacctct tcatttcctc aattataaat tatgtacaga
     7261 ttacattata ataaatggcg agcaactatt caagagatat ttcattagta tttttttaaa
     7321 caatctttat acattttaat atgatattat accaaattta ttaggatttt attcataaaa
     7381 atcagtctat tttttatgtt tattcattgt tattttcatc caattttttt attttcgata
     7441 tggatacttc atatgccatt tttttgacca cattattttc atctattttt ttctcatatt
     7501 ctctactttg aaccctaccc caaagctgta ttctatcacc aacctttaga ttctttgcaa
     7561 atttagcatt tctaccccaa actattgatg gtatataatc agatttatta taaggtctgt
     7621 ttatagcaac taataaatcg gttatttccc ttcctaaagg tgtcttccta tacacaggtt
     7681 ccttacatac atatccatct aaaaatatac tattagggtc tttattttcc tcgtctatgc
     7741 tttttatttc tctgacaaac actgtaagca ctaatctatt tttattattt aatgttttgt
     7801 tatatgatct taattggcct acgacattga ctaaattttg tttatcaagg tcaatatctt
     7861 ggagaagtct ttctgataca gtcattggaa gtatatcaaa agaatcgctt agtctgttta
     7921 tttttatttt catattataa aatttttctc caaatatctc atggctaaat tctagcttat
     7981 tgtctaactc ccctcttaag tttactacgt tattctcatc tttaacagct atcatatttt
     8041 atccctccac aattgttaat tcttatattt ctggtatcag cttatataat aaatatattt
     8101 ataagggatg tattttatta caaatctttg attgctgttt aaaagttttt atttagttat
     8161 aaatttcatt taatatttca cttttataat tataaaatta ttatcttttt gtactacata
     8221 tactaattaa actacctatt tcagttttgt attaattata aaaatcctat tatataatta
     8281 ataagtcata tataacttaa atttattcac tctatataag caacttcaac gaattaaatt
     8341 tattcaaata attcagatga atattgagtc attataaact tatttttctt aattataagt
     8401 tatattagac ttattacagc ttatattttt attaatctgt attaatatat gaacatttat
     8461 tgaacttatt gattataaaa tttaaatatt tagctttaaa ttatgcttta ttctttgaaa
     8521 atacaacgtt ttttacatta aatctactaa atcactatat atattacata attggcatgt
     8581 taattgcttt atattaattt agcaaataaa aaactgccct aaaatattaa ttcaatattt
     8641 taaagcagtt tataatcttt attattagct gtaatattta ataaacacta agtagtcttt
     8701 aactaagcag tctttttgtt tttatttgca gccattatca ttgtagcaga agtataagct
     8761 ataactacta ttactaatgc ttttaatata tccattggta gagtttttac tatatatgca
     8821 gctacgaaaa ctcctattaa accacatata gctattataa ctgatgcttt tttagtatat
     8881 gcatcttctt ttataaattt catacttgca actggcatta ataatgcaca agaacccata
     8941 actattggga atgcaacttt tgcagacatt cctaagaaat aaaccattgc catacctgga
     9001 gcatatagac ctataccagc tgtcattaaa gctcctagta taaagttacc tattacacct
     9061 attaccaatt taacaccagt aagacctaat tcatttcctc cacctggtaa tacgttaatc
     9121 caaggatgac ctaataacat taatattgct gttaatgcta aagttacacc cataacaagt
     9181 tgtatttttc tctcgtccat cttagctatt attcctgcac ctatatatga accaactgct
     9241 gctgccacaa ccatagatac taaagtaaca ccatcaactg gtatgattga tgtaaatatg
     9301 aatgcttctg taacaactgg aatagtatgt gctacgttta atgtaccagg cattttttta
     9361 tctggtatat ttaactttaa agcctttgac attgctattg ttggagcaaa tgaccctatt
     9421 cctaatgtat caaagaagtc tgttataaat cctgttacag caacttttgg agtactttgt
     9481 tcttctagtt tcccctcttt gtttgcttta gctacgtctt taccaaacac aactgcaaag
     9541 attgctgcga atactacata taatgccttt aagattgcta ccataatcca tcctcctatt
     9601 tttttatttt ttcatatatt ctgaatctta tagcctaaaa gctatagaat agcaaccgac
     9661 aagtggctac tattctattt taatttccta atttatttat tacttattta agaataaatc
     9721 catgtttaag tgggtcttct tcatctatta caaaatgatt aaatccagtt atataagcag
     9781 aaccagttat tttaggtact acagcattga aatctgcaac tttagtttct tcaactattt
     9841 cacctttgaa taaagttcct aatatacttt catatacgaa tttttctcct acttttaatt
     9901 cacctttagc atgtaaagta gctaatttag cacttgttcc agttccacat ggagatctgt
     9961 caacttgacc ttgaccaaat ataactacat ttttgtaagt agcttctgga tgagttggct
    10021 catcatatat ttcaactaag tctacagttt ttatatgagc taaagttgga tgttgtattt
    10081 ctattttctc atttattata tctctaagtt tcatagctag ttcagttaat ttaccagcat
    10141 tttgaggttc gatttttaaa cctaattgac ttgcatgtat tatagcaaag aagcttccac
    10201 caaatgatat gtcaaattta acagtcccaa cacctggtaa gtcaacttca acaccttctt
    10261 tatataagaa agctggtacg tttaagaatg atacttcttt agcttttcca tctacaactg
    10321 taacgtctcc tcttattatt cctgctggag cttccataac tacatgagtt acaggctcta
    10381 ctgctggaac tacacctgtt tctatagctg ctgtcatagc tcctattgta ccatggccac
    10441 acatgttaag gtatccacca ccatccatga agattattcc aaagtcagca tctgggcaac
    10501 aaggttgagt cattacagaa ccaaacatat cattatgtcc tcttggctct aacattatag
    10561 cagttcttaa ataatctaga ttttcctcta aatattcttt tttctcaggc atagaatttc
    10621 cttttatgtt aggtattcca cctacaacta ttctagttgc ttcacctgct gtatgagagt
    10681 ctatagcttg tatacttctg ctaaatttca tatcaaattc ccccttaggt ttattttgcg
    10741 tctttacgca tttttaattt taggaaagcc aatgcttttt taacatcaac ttcatccatg
    10801 tgattgtctc caactacttc tgtttctatg tagcctgttg tctttttata atcaattatg
    10861 gtagctttat ccaaatatgg attggtaatt actaatccat ctgctcccat aatagtaaga
    10921 cctactgcag gtatatctga ttttacaaac tctgctatag catttgtaaa atcaatgtgc
    10981 tggtttcctg ccatatctaa agttataatc actccatcag gtcgcaatga ttcaatccat
    11041 cttccaagtc tagttgctaa aaatgttttc cattcattgt gctctgatgt cccaactaca
    11101 accactccta acaagtctat gtcagaatca ttatctatca aatctagtaa cgggtctcta
    11161 aatatatgaa gtgatgtgtt tttcattgat gtagaaattc ccacaaaact cattccctta
    11221 cttaaatttt ttatccatgt tttctcattt taagttttaa aaatgctaaa gcttttttag
    11281 catctatttc atttgtgttg ttttctccaa ctacttctgt ctcaatacct tcctttgatt
    11341 tgttcatatc aactatggta tccatatatt gattgcttac aacaaactta gcttgagtcc
    11401 cattaaatgt aactccaact acaggtatat ctctttttcc tatttcctca aatgtgttag
    11461 cgtagtcaac atgtgagttt ccccaaccat ctgatgaaac tatagctcca tctactctca
    11521 tggcttccag ccaagcggcc gttctttgtc ccacaaaggt tttattttca tttccatctg
    11581 gagttcctac tactattact ccaagtaaat ctacatcctt atcactttca actatgtcta
    11641 aaagtgggtc tctaaagtga tgaagagatg tttcttttgt tgaaggtcct attcccataa
    11701 tatccacctc tcttaagtca tagctctaag ggcaccatct ctgtattcat taggagatat
    11761 aatcataggt acatttccca tatctataat tgatgttcct ccttcaaatc cactaggttc
    11821 ctttgagaat aactgattgt catacatagc accttgacct gctatttgtt ttactatgac
    11881 aacctttttt gcatttggtc gaattttgtc aaaatattca cgaacttgag tagcatttct
    11941 tccgtcttcc attttcaaag acgctcttat ttcttgtata aaatcatcac atgctctgaa
    12001 tgctgcaagt ggaagtgttc tttcaaaagg taaacctccc tttaaagtta catctacatg
    12061 gattatataa tcttcaactg atggagttcc atatctccca aataccattt ggtctttcaa
    12121 aattccttct gaagaaccaa attcatgcat ttgatttcca tcttcatctg caccagttaa
    12181 cattacatat acacccgtta aagtatgtgt gataccctct cccagtctgc ctaaaacttt
    12241 tgttgatatt ggtataatgt ccataatagt attaatttct ctatcataat ctccaggttt
    12301 tataatgtct acttttatgt ctgttattaa ctcttctctt tcttttattt catctatact
    12361 tgataaatct attgtaagta catctttctt tatagaagtt tttgaaccga aattaacttc
    12421 attcatatga aacggtttta taacaagtct tctcattatt ttttcttcca taatatccac
    12481 ctttgttctt aaaacccctc tcctaaccgt gtaggagaag ggttctatat tttcaaatat
    12541 aaattacatt ttaaacgtga gctttatatt cgtatggtaa tggaactatc ttaccagcag
    12601 atggtattgc aactaattgc tctaatgtat ctcttaatat atgtgtttgc atttctatat
    12661 tatgtggttc accagcatta gcacccattg gaactaatgg agcaactgct ctaggagttc
    12721 cgttttgtct aactactgga ggaagagctg ctattattat tgtaggtatt ccagcttcct
    12781 ctattgctct ctgcacgatc acggcagttc tatggcaagt acctcagcca gctgtcataa
    12841 ctacaccgtc tactccctct tccttaagtt tagcagcgat agcaggacca gtttcttcag
    12901 tgaagacatg ttggtttcct ccaccaccca tgaatgcata gtgcatagga gctactcctt
    12961 tgataaatcc ttctgcagct aattcatgta atctatctat agggaacata cagtttatat
    13021 ctttgtttac atctccattg tcatatccac catgtgatac catcatttca tcaactgtag
    13081 ctgtattagg tatagctcta aatgtagtat ctcctgctag attaaatctc ttgtcagatt
    13141 ttaaatgaac accagctgct gtagctaaag ctatagtcat atcttttaat tctttagtta
    13201 caggagtcca aactggagga ggtgttattg gaacgaatat ttcagattga agtccttgta
    13261 ctgttgtaag gctcatatat ttcctctccc ttctattttc aaacgattat ttattatttt
    13321 tcttcttgtt ttgattgcat ttctgcttgt ttttcttttt ctctcctaat attttctaca
    13381 tactcttgat taggctctgg acttaatacc tcaggatagc ttagcatgaa tccaacttct
    13441 tgacctatct taagttcgta gtcagttata agcattctat taggtatttt aaattgtcca
    13501 agtctacctt ttaggtctat agtcactcca ccacctttga tgtcaactat aataccttca
    13561 taaaaagtct ctgatgagat atattttaac ctatccatta taattctacc tctctatact
    13621 gttttaaact tggatctaaa tttatgttat tgtctaaatc ttagttagta tctaaatttt
    13681 agttttcgtc tttttcgtat atttctcttc tcttcttact cattggtaga gattgctcat
    13741 tctcttctaa tactattttt tctcctgtaa ctttttctat agcttctatg ttatttaatt
    13801 taacatttgg attccatttt ctttcaggag ctttaacttc tacaccttct atagcatttt
    13861 taagcatagc cattattcta acagcatctt ctggagctaa agtgttgtta gataatattt
    13921 cattctctat accttgctta gacttattgt tgtctaccat gtgagtcatg tatttattac
    13981 caacaactag agcaccttga acagctgaga aacttacacc aactactggt atacctctca
    14041 tacctatttg ctctatgtga gatgcgaaat ctatatggtt gtttccgaaa ccttcagtag
    14101 ttactacagc tccatcaact tccatagctt caactaacat acctaatctc ttagatacat
    14161 agaatttctc agcatttact tgtggagaac caacaaatac aacacctact aaatctattt
    14221 cttcgtcttc catagctctt attactaatg gctctctcca gtaatgtctt gacatttctt
    14281 ttgatgcagg tcctatacaa gttaatgcat ggataccacc atctaatact tcaagtggag
    14341 ataatacaac tggcatgttt cctaagtcaa cgtttggttg agctcctaat gtaccaactg
    14401 gctcaactgg taatattagg ttatcatgca ttgcaccttg tcccattatt tcttttataa
    14461 caacaacttt ctttttacct tctcttctgt attgctctat tacttcttca tcaactacta
    14521 aagagttgtc aactttcttt aatgcttctc ttatttcttg agttacatag tcaaatgcac
    14581 ggtgagcagc taaaggtcct ggtctttcca tgttagttcc tgcttttatt gttacttgac
    14641 ctttgatgaa tatttcacct ttgtcagcag cacctggtct accccacatt atagtagtat
    14701 ttaactcacc ttctgaagaa ccaaattcac ctatttgaac tccatcttca tctgtaccag
    14761 ttaataccat tacagctcca tctataactc tagttatacc tgaacctaat tcgccttctt
    14821 ctttagtagc gattggttgt atatctaata cagcttcact gtaagtttca tatttatcag
    14881 gagttattat ttctaacttc atatctacaa ctaactcttg agtttcatta gcttctttac
    14941 atatttcttc tgcgtttctg atgtataaag tagttccttc tattttagtt tcatcagcaa
    15001 attcaacttt atctatttta aagtgttttt tagttaagct tcttaaaagt ttcttttctt
    15061 caacttttgg agctacttct gctgctgcac ttgccactgg agcagcaacg tttgctactg
    15121 gagcagcaac tcctgcttga ccagctactg ataaaggtat ctctaagctt atgttcttac
    15181 cttcacctat gtgtatttta actgtttcac ctgcaactcc tgtgcttact ggaactactg
    15241 ctgcttctga tactggagct gcttcttcta ctgtttcttc tactacttct tctttagcct
    15301 ctcctgcttt gtatccttct acgttatctg tagtcattgg agaaagtgca tctaaagttt
    15361 cttttaactt agctcctagt acttgaccta tagttaatcc attttctggt attgttaata
    15421 atccagaatc ctctaagtct gcaaatattg ctggatcttc taagttttct ggcgctataa
    15481 ttgttcccgc ttcaaatcta caacaacaaa ctgctgggtc atttgcatgg gcttgagctg
    15541 tttctaaagt tattgacata gtataaaata cctccttaca ttattttctt atttattatt
    15601 ttaaatctca attcctcaac aggtaacccc ttaactgaga aattaagtaa attaaaacct
    15661 acataatttg ttatgattaa tattattttt ttctcactca aagtcacttt atattataag
    15721 caattcctat gccaacttat taacaaaaag attttttcta taatagattc ttcatctatc
    15781 gctattttta gccaaatatt atataaatat ttatttaaaa tatgttattt tttgtatttg
    15841 taaacatttt ctcaaacaaa aaaagtgtca attaatcaac actttttcat tttttttaac
    15901 acatctatat acacaacact tatacaagtg ttggctttac taggttttaa attaaagttt
    15961 atcattttgt caaaatttag tcatatgtca tattttagac acatctattt tgtattggtc
    16021 tatcttataa tacaaagttg ttctgggtat atttaatatc ttagctgctt tagctttatt
    16081 tccattagac attttaagtg ccttggttat attctttatt tcaatttttt gagttgcctt
    16141 cgttaaatct aagggatact cttcttcttc agtactatta tttgtagaat ccatcatata
    16201 acttggtaca tcatctacat ctattttaga attttgtgac aatacaacaa tattttcaat
    16261 cgtatttttt aattctctaa tattaccttt ccatctataa ttctgaaata tatctattac
    16321 atctttgcta attgtaagaa caggcttatt attttgttta catatctcct ctaaaaagct
    16381 atgaaccaat aatcctatgt cttcttttct ctctctaagt ggaggaatct ttatttcaac
    16441 aacatttaat ctatagtata aatcttctct aaatttttct gcctttacca ttttactcaa
    16501 atctttattg gtagctgata ttattctagg atttattttt attgtggtat ctccaccaac
    16561 tcttcttatt tctttttcct gtaatactct aagcaacttt gcttgcatac taagaggtaa
    16621 atcggcaatt tcatctaaaa atacagttcc atcttttgca agttcaaata tacctattcg
    16681 acccttttta cttgctcctg taaatgcacc tgattcatac ccaaaaaact cactttcaaa
    16741 taactcattt ggtatggcac tacagttaac aggtataaat tgaccttttc tctcactata
    16801 atcatgaata gctcttgcaa atacttcttt acccgtacca ctttcacccc aaataaatat
    16861 gctactattt gttctagcca cttgttttgc aatcgctttc gatttttcca atttataact
    16921 tttacctaaa atcttatcaa aactaccttt agataaattt ttgacttcgt tctttagata
    16981 ttttaatgta tcatttactt tttcaagttc aagagctaat atcttagctt ctgtaacatc
    17041 aacttctgta catacaacac cgataaattc ttctttataa aatataggat ttgcatgaac
    17101 taatgcatac atattttctt ttttatctgt aaaatacaag tcactcattc caactttact
    17161 atttagtact ttttctgaaa tagtattttc caaaaattca ttcatcggtc gaccaactat
    17221 atcttcagac tttatatcat acctttcctc cataaactta ttccacaaga taacaacacc
    17281 ttcgttattt atagcacaaa ttccttcttt aatttgacct ataatatact tcaaagtcaa
    17341 tccataatct tctaaatgca tatatagata gtccctaatg tgctcttgtt ttagaactcc
    17401 aataatttta ttatctctaa gaacaggaag aatccctata ttttttaata tcattatatc
    17461 tctacattca tctaaggtta aaccttcgtt gacatatatt acatccttct tcattataag
    17521 ttttactggt tgaccttcat actttttatg catctcataa agattatgta tatccgtcat
    17581 ggatataatg ccttttaatt ggtcagatga atctattacc attagagttt ttgtgttgct
    17641 ttttatcatt tcttttattg catcttcaat tcttgtgtct tcgtctatag ttgtaaattt
    17701 tgtatccatt acctcttcta ctttttttac ttctggtatc gaaaacataa agtccccccc
    17761 tttatagtag tacctcatca aaacttattt atatatattt attctagcat attataataa
    17821 ttatttatta aataattatt attaaaattt attaagtaat tagcatttaa atttatataa
    17881 tcactttaaa atttataatt aaatttatac aaatgaaatc aaatgaatta tacccttagt
    17941 atattatttt ttcaatacta ttttcacctt caaaacattt ttctattcat caaacaatta
    18001 atgaatgcct gtatccaatc ataaatttaa gaatataatt aaaatagata tttttaaaca
    18061 aactatattt gcatattata tttacataaa aaagtcccaa aatgacttat aaatcaattt
    18121 gagacttttt attttaaact taataataat ataaattaat ttctttttat aaattaaggc
    18181 gtaaaaccac tataccttta ggttggtgga tgtaaaccta tcccttactt tgtatgtatt
    18241 tttcaatcat ttctttagaa acatttccta cactgaaagc aaagtatcca tctgagcaaa
    18301 aagttttttc tgtatttaca tacaaatatc aaatgtacca ataacaaaca cttagaatgg
    18361 tttctactaa cataattcac aactccaatt caatcccttc ttaaatatat atggtttaat
    18421 tagttttaca tttggcactt ttttgatttc ttttaaagct atatattgcc ctcaaaatac
    18481 attaaaaaac atccttagaa gtaattttta agttttactt ctaaagatgt ctaacttcta
    18541 tttatctatt attttatttt taatcttacg tcacctttta ttcttcttat taatgggtga
    18601 ttaactgttc tcattacatg gtcagtaata tgatatacac ctaactttaa ttttggtgca
    18661 gaacccatta ctgtgttact acagtcagta cagtttccta ttaatataac ttctgctcca
    18721 gctttcttaa attcaataca tttttgagct tgtcctggac agtgtcctgg attttcacat
    18781 tttaatgcac ctttaatttc ttgagcttgt ttacattttt gaactgatac tatatcagta
    18841 actcccattt tagttgctat atctctcatt ctctcttcat taggtccaca tgcacagact
    18901 aaaagaccca tttttctctt ttcattaaca aatggcatag taactattat accaccacta
    18961 gttttagtta ttggagcatc taaagtagta gctttaccag tgaaaggtcc tcctaggatt
    19021 atttcaccat attcaccttt tattccacca gctctttcaa ttaattctcc gacagttgtt
    19081 ccaattggca catcttcaaa tactatagac tcttttccac tgtttaattg accaactaca
    19141 gttatatttt tagatataac tggtcttttt tgctcaacag cctctactat tctagttagt
    19201 gtttctacgt ttattactac tgcattagcc tctgaaggta attgagttgg ctcaagtaat
    19261 tttcctagaa cgtctcttac tattgctctc tcttctccca ttgggtacat atcaactagt
    19321 tctgcaactt ctatgttgtc tcctggcttt attacttttt tgaaagcttc tattgctttt
    19381 ggatgcttgc tttttattgc tagcatacct tttccagcat tagtaacttc catagcatat
    19441 tttatacctt gataaactat ttctggtctt tcttctattt cttttatatt atgagctaat
    19501 aaaggttcac attcagctgc atttgctaat attgttccac catttaaatc tatgtttaat
    19561 tttacatgag tagggaatcc tgctccaccc attcctacta ctccagcttc tttaattaag
    19621 tcaagtatac cttctccttt taatggttca aaagtatctt cttgtacttc atcagcttca
    19681 attactatcg cttggtcatt tatttcactt atttttccac taacactggc ataaatattt
    19741 gcccctaatc cagttggttc tgcgattaga gttccttttt ttactacatc tccaacactt
    19801 actactggct tatctggacc accaacgtgt tgttttaata aaatagaata tagtttgttc
    19861 aactagtacg cccccttaag tatattaatt tttttataag ctgttcaaat aatgttaatg
    19921 ctatttttct attataaggt cttaacatat tgtttatttc tatagaacat atcgcttatt
    19981 aacaaagcaa tttctatgcc aacttttaaa caaacttata ccctttggaa atactgtctt
    20041 acagcattca ttaattcttc taaattttta aatccatcaa aaaaaagtca attattagac
    20101 acttttttaa tcaatttaat ctataattat tgatattgca tacatgtata aaaagtgtca
    20161 aaaaatagac accgtctttt tatcgacact tttctaacat atactatata atttatcaca
    20221 actttactta aaatatacat ttattactta ttaattctta gttttttgca ctccattgga
    20281 atcaactaca taattatctt tatacaacaa atcagatatt ttgactagac tgtatccatc
    20341 tttttttagt cgacttatta tagtatccaa atagttatct acatcattta tattagcatg
    20401 gaataaaact attgaaccag gttgagattc ttttattact ttctcaatta catgatttgg
    20461 tccaagctcc ttccaatcta tagaatctac atcccactta attactttat aacctaaatc
    20521 actacaaatg tccatagctt tattgtttac gtccccaaaa ggaggtctaa ataaattagt
    20581 cttttttcct gttatattat atattttttc tgatgtagtt tctatctctt ttgttatgtc
    20641 ttcttttgat atttccttca aattggcatg agtgtttgaa tgatttccaa tttcatgtcc
    20701 tttttcatct atagctttta caatttcttc attatcatcc acccaactac caactaaaaa
    20761 gaaggtagct tttacattat gtttatctaa aatttttaaa atatcatcca tattatcagt
    20821 tccccatgct acatcaaaac tcaaggctat ttttttctca tttgtatcaa ctttatatat
    20881 aggcattttt gaattgtcgt atttagaaca tatgtatttt attccataaa caaaaacaaa
    20941 tattaacact aataataatg aaaaaaataa aacactatat atcaaagctt tagtcctttt
    21001 aacttctctt ttcatactat tccccctttg aaataatttc ttctatattt aaaatttatt
    21061 ttttttcagc tcaaaaaagt actgtaatat ttaatttata agacaataac taaaaaaata
    21121 aaacctatat tgacctaatt aaactctcta aaatactcat ttatttaatt tttttatatt
    21181 ttttacattt ttacctttat ttttctgtat atattatttt tattttggag aaattagtat
    21241 taacatcaca taaataaaag tgttgttaga catcataaac taattatttg aggaggaaat
    21301 ttactatgtc aaattcaaac agaacagtag ttccagaagc aaaagctgct ttaaaccaaa
    21361 tgaaattaga aatagctaac gaaataggtt tatctaacta tgaaaacata gataaaggta
    21421 acttaacagc tagagaaaat ggatatgttg gtggatatat gactaagaaa ttagttgaaa
    21481 tggctgaaag acaaatggct ggaaaataaa tagtaaattt tgacacctgg gtatcaacag
    21541 ggctgctaat tagcagccct gtttctctat atttatttat aaaattgttt tatatgaatt
    21601 attaaagatt aataatacaa tacaaattgt tcttttaatt ttgtacaaat tagtttaata
    21661 tattatatat agaaatagtt tgacggagga tgatatttat gtttgaaaac tcgtctgaag
    21721 aattagccta tcacaaactt ttaattttat atatattaga aaaaattaaa atggatttaa
    21781 ctaattctca aataactcaa gtagtattag agactgagat gatgaattat ttttcattac
    21841 aacagctttt atctcagctt atggaatcta agtttttgac tacatataaa gactctgaca
    21901 gagaatatta tgctcttact caaagaggcg tagaaagtct agaatacttc tttaatcgaa
    21961 tacctactag tgttactgaa aaaatagaca agtatataga ttctaacaaa gaaaatctac
    22021 tagcagatac tcaagtaaag tctagttttg taaaacaaag tgataatgaa tttattgtca
    22081 accttagagt catagaaaat cagtctaact taatagattt aaatctaaat gtttcatcag
    22141 agaaacaagc aaaacttatt tgcaataact ggaaaaataa tgcatcttat atgtatgccg
    22201 aagttatcga tttacttata agagacatac attaaagcct acaaacaaat tatagttgta
    22261 ggctcttttc ctaccttgat ttcttttatt aatttattgt ttgcagtttc ataaactttt
    22321 actgaatttt cttgtgtatc tgatacaaat agtagctttt catctttaga tatttctaag
    22381 ccttgaggaa tcccatttat ttcaatattt ccaatgtatc tactcgttgt ataatctaaa
    22441 attcttacat tattataacc caaatcagca acataaactt ttttgccact ataattaaat
    22501 cttatttcta ctggtaataa aaattcatat aatacctttt ttatatccat gcttacttca
    22561 tctattatta taagctttcc atcaagtgtt gatatataca tttctttctt ttgtttatca
    22621 agctctatat gccaagctct aaagtccata tttattttct tttgtatatt tttattaatt
    22681 gtatctatac atactatcga gtttatacac ggtacatata attttttact ttctctatca
    22741 aagtcaaatc catgtggcat attatcaact ccaataattc ctattggatt taatgtgttt
    22801 ttatctagta catatatact attagaatct tcatttgcca caaacaattc attatcacta
    22861 agtacaactt gactaagact tcctcctata gagacagtat caattatttt atcattactt
    22921 aaatctaaga cataaagtat cccattactt gaactaggta tgtatattaa atttttttct
    22981 ttttctatgc aaaaatggtg tggatatata ttatcttcta atactatttc tttttctagt
    23041 tcaagtgtag aataatcaac tatgctaata ctctttgata agtagttaga aatatagatt
    23101 ttcatataac ccctcctctc tacaatacat atactacaat aatatattat ttcattagct
    23161 tgtattatgc tttatagttg cattattacg catatatttg gtattattat tattgttaaa
    23221 aaaagaaata atatttaatg gaggtctttt taatgaaagt aacatttaat ccaagtggtg
    23281 tatgttgtag agaaatgatt tttgaagttg atgaaaataa tgtgattgtt gatgctgagt
    23341 ttataggagg atgtaatggt aatttatcag gacttagaag cttaataatc ggccaaaatg
    23401 ctcttgaagt tgctgataaa ttaaacggta ttgactgtgg tggaaaaggt acttcttgcc
    23461 cagaccaatt atctaaggct atacgtcaat ctatataatt acttatataa acatcagtaa
    23521 aattattaaa aacttacttt atataaaaag agttgtccat tttttagaca actctttttt
    23581 atatctttat ttgtatattt attttataaa attataattt ctttactaaa gttctcactg
    23641 taccaatcat atataatgaa cctgcactta ttataatatc atcctcactt gatgtttcta
    23701 atgtataatt tactgcatcc tctatctcat gctttgatgt tacatcatct acatatttta
    23761 atactttttc tcttaatata tctgaattta tggcccttgg gttatttggt gttgttgtta
    23821 ttaccttatt aaaatgtggc aacaatatct ctaaaacact atcaatatct ttatcttcta
    23881 acatacctat taataaggtt aattttctac ctttaaaatt cttatcaagt gcttttgcca
    23941 aagattttgc tccatcttca ttatgtgcac catctattat aaaaattgga ttttctttta
    24001 tcttttctat tcttcctggc catttagtat ttataagtcc ttttcttata gattcttcat
    24061 ttatatttgc taatttattt atgtctttta gatattttat tacactaatt gccaagatag
    24121 aattgtttat ttgatgttca cctatcaatt ttatttcaag gtctctataa gtttctttca
    24181 ttacagtaca atcgtatatt tgagaattta tatctgattt ttttatgttt atatcatcaa
    24241 aatcaacttc tatatattta gcttttttct ctttacaaac tgactttata acatccttcg
    24301 cttcatcagt ctggtcatat actagtacta ctccattttc ctttattatt ccagcctttt
    24361 cgtacgctat tttttctatt gtatctccaa gtatacctgt atggtccaaa cttatagata
    24421 ctatcacact tacaagtgat tttgttatta tatttgtagc atcatatctg ccacctaaac
    24481 caacttctaa tgccacaaag tctacctttt gttctgaata gtaataaaat gccattgcag
    24541 taaccacttc aaattctgtt ggatatgcat agccttcttt taccataatc tctatttttt
    24601 cttttattaa ctcaattatt ctagcaacat catcctgtgg tatattttgt ccatttactc
    24661 ttatacgctc agtaaaagtt tctaaatatg gagatgtata taaaccaact ttatatccac
    24721 actctcttag tatattagaa acaaaagaac acacagaacc ttttccatta gttccagcta
    24781 catgtattat attcaaagtt tcttgtggat ttcctaataa ttctaataac tttccgatat
    24841 tttctaatcc taatcttata ccgaatttat tagtttgtga tatgtactct aatgcttctt
    24901 catatttcat tatctaactc cccctgtatt ggcattttct cttatgctat ctaattatag
    24961 tatatttttt acttttaatc taccgacaaa gaatacatat aatttaatac cttctacatt
    25021 aaatttagct acaaatcttt atttataagt ttttatatct ttccactaat tcagtcagtg
    25081 tatatattga aactaagtca tattttgaga tgtccatata attaaacttt atgtcaaatc
    25141 tatgctctag ctttttcaac agattaaaac aattatcata aaccaaacct atctccttat
    25201 taaaaaggct acccttaaag agtttttcat tattatcttc aatatctaaa caatccctaa
    25261 caacgtcagc aactttcata agaagagcat tttctttgtc atacaaatcc aatttaaagt
    25321 ttacaattct actacactca tcaaaatcac aactatccca atgatttcta gttgctaatg
    25381 attcaagctt atcatttaaa tcagatattg ttatgcctgg tttttctgat aatatcttag
    25441 ctattttacc agtaagcttt gctgataaat aactattaca ttttggtggt aatctatagg
    25501 aattatttat atcacaactt atatatgaat tgctatccat aacacattga acatcatatt
    25561 ttttgttgta ccaaaatgaa tcatctccat ctaaagtaaa tcctcttaca cctataacat
    25621 tgttaaacat agctggataa cttaaatcaa aatcattagc gagtgaacat actattattt
    25681 ttccttttct aaacaattcg taacaaactt caaataagcc cttaacactc tctactccta
    25741 tgactgataa acttaaatta attaatctta tgttagtgtc taaaaggtat cttaatgctt
    25801 cttcaagaac ttttatattt gtaataccat cttttctcaa aatttttatt acaaataact
    25861 ctacatcttc atactctttc tttattattg atgcacaagc agttccatga ccatcttcat
    25921 catcaaattt atctgatata aagatataat catgcataca ttcaaaagca attcctccaa
    25981 ctaaattatc ttttaagtaa tcatgttctt tgtctattcc tgtatctaat actgcaacct
    26041 taactttatt attcatatca catatattct ccattacaaa agtttttaat atatctatgt
    26101 taatagttca tcttaaactt tgatttaagt tgcacaattt atcttttaaa tgctatattt
    26161 cttgctaaaa acataaaata agtacaccat atatttaatt tatatttatt atatcaatta
    26221 ttatcattaa atggttaaat gttaagataa aatttttaga tttatatcac aatttaggat
    26281 tatttgtaaa aaaggagatt atctttttat tagacaatcc ccttgtatat tttattaata
    26341 tttatctatg attaagcatc aattttattt tatacttttt gattttaata ctatacatct
    26401 aaatcttatt tagggggaac aattatttat atgatataaa aatgctaatt tgaatgaact
    26461 tgtcttataa tcagttttat aaaatacacc attctacaaa gtatgaatca aaaggtgaaa
    26521 aaatactaaa aataataaat caacatcaat tttaaccaat atatgaaaaa cttataccaa
    26581 gtatgcataa aaactaatat aaatattatt ttaacaacta atacttacac ctttatatat
    26641 tatatcatat ttcaataaat aaattgcata aaaggaaatc ttttcataga attaaaccat
    26701 ttattaattc attactatag gttcaataaa ctataagatg tcgctttaat atttatatta
    26761 tactccatta aatattaata taattaatta aagtatgcat agctaaatga aacaaatatc
    26821 tatagagttt tataaatagt cattatttta aaaaggtaat catattctaa aaatacatat
    26881 aatgcatata aaaatcaata atagtatatt aataatcagg ctactaatta ataatcatgc
    26941 tactgtaatg gaaactctac atatacatat taaacaatat taaaagtcta taaactgata
    27001 ttttgcataa taaaactgtc ttaatataaa taacatttta tatattaaga cagttttaat
    27061 caatagccct gtgatgacat taaatctttt ttacgatatt ttcaattacc tttttaaaat
    27121 taatacatta tatcacataa caagcttgtt aatgctactt ttaaatcttt aagtctatac
    27181 ttacttatag gtataaattg ttcattaata gtaatcatat tatccctaag atcttctatt
    27241 cttcttaaat taacaataaa acttgtatga catctaaaaa agccattttc acacagtaat
    27301 ttttctgctt gtttcatgct catattagct ttataatctc tacctattgt atgtacaact
    27361 aaatctctct ttacagtttc aacatataaa atagaatcta tcagtattct attaaatcct
    27421 tttttactat ttaaaactat ataacgctcc ttctttcttt gaaggttatc aatacaaaga
    27481 tttacaccca ttgcaaagtt actatactct ataggcttta ctaaatatct ataagcacga
    27541 acctcataac cttggggggc atactctgaa aaagctgttg taaatataat ttctactttt
    27601 tcatcaaact ttcttatttt tttagccacc tcaattccat tgatatcttt catttggata
    27661 tctaaaaata taatatcaat tttttctggg tatttggata ttaaatcttc tccacaggaa
    27721 aattccagta tttgataatt tagacatctt tcagacaaaa gtttttttgt aaactctttt
    27781 agtatgcttc tttgtatttt ttcgtcatca catataacta ccctgaacat aatatcacct
    27841 ccaaatctaa aatatcattt agtttacttt atttcaattt ccaaactgta ctcactagct
    27901 ttcaaattta aatttcttta taaatttaag ttgtcgatta aactacttat agaaattctc
    27961 tttaatattt aaacttaaat tacgataaat tcctatactt ttctagatat attatgtaaa
    28021 aaaatatagt aaaataaata taatatgtat t
//
LOCUS       DAMJWO010000055        27758 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.056, whole genome shotgun sequence.
ACCESSION   DAMJWO010000055 DAMJWO010000000
VERSION     DAMJWO010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27758
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.056"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            46..120
                     /locus_tag="PC366_002409"
     tRNA            46..120
                     /locus_tag="PC366_002409"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:78..80,aa:Thr,seq:tgt)
     gene            complement(280..957)
                     /gene="srtB"
                     /locus_tag="PC366_002410"
     CDS             complement(280..957)
                     /gene="srtB"
                     /locus_tag="PC366_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HDF2577915.1"
                     /translation="MKKLYRIVINIILVLVILYSGFNIYSKLTKYNHDTKTSSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSIDDKNIIIYGHNMKNKTMFNNLNKFKDADFFKNNNKIKITLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNNESDYQNYINDITSKSLYKSPIKVNSNDKIVTLSTCTYEFDDARM
                     VIHGRLI"
     gene            1089..1423
                     /gene="rnpB"
                     /locus_tag="PC366_002411"
     ncRNA           1089..1423
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="PC366_002411"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            1701..4244
                     /locus_tag="PC366_002412"
     CDS             1701..4244
                     /locus_tag="PC366_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HDF2577916.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSERRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVPNNVEENNEQDKVEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKSNDIESKFIDKLNSLNNESISQTIHNEYK
                     KLCGLEELHSVEGYGFGKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAQNLIKDNYSELENHEIASKRTRRNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDAEEGAKEEVDSNNQDIGDVVEDKDTTDKEYDSNKEDIIE
                     PENKKSKKKAKLFGFIKKDNEEVEQEEENLNDISPDIILDKPVENHQAKSEEIEQNEL
                     KEIKQEEPSQHIEEERSVKIEKPINNNLDEKVSSNNESKLEKESKNLEDKKAKEIKEE
                     KLENEKSVVIPIKKKENSNKKSKNSSKDKYRENKKEMKNYVSDKEDSLDDEEVVSKKS
                     RLKETIIAVVIVVIVGVGYFITVGNNKKNDKENIPKSSTQQQANNKLTEEEKKAQAEK
                     EKKEAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGVYYTVYAGSLKVEKTAKETAKE
                     YEAKGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLE
                     ELKESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            4366..6357
                     /locus_tag="PC366_002413"
     CDS             4366..6357
                     /locus_tag="PC366_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577917.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNEDTGVKYIYSFSDNKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKFYMGGINKDNEKFIFISGKNRFEIN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCDIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLKDIENEIVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKVLLNLSKNMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEQRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            6347..6667
                     /locus_tag="PC366_002414"
     CDS             6347..6667
                     /locus_tag="PC366_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577918.1"
                     /translation="MSSKYNVWTFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSGLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYLDEDIDSDIKGI
                     LDEI"
     gene            6865..7734
                     /gene="galU"
                     /locus_tag="PC366_002415"
     CDS             6865..7734
                     /gene="galU"
                     /locus_tag="PC366_002415"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDF2577919.1"
                     /translation="MTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIEEA
                     IESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHYIR
                     QKEPKGLGHAIYCAKSFIGDEPFAVLLGDDIVDSDVPCLKQLIDTYNEYKTTVLGVQK
                     IAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFSILEK
                     QTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENLKD
                     DLMDYMRKKVSEK"
     gene            7759..8772
                     /gene="galE"
                     /locus_tag="PC366_002416"
     CDS             7759..8772
                     /gene="galE"
                     /locus_tag="PC366_002416"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HDF2577920.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNSIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHVVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLAAGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            8884..10818
                     /locus_tag="PC366_002417"
     CDS             8884..10818
                     /locus_tag="PC366_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HDF2577921.1"
                     /translation="MKKSLKKYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKAINNKKYYLGTDGARVSGWKVIDGKTYYFNSDGVMQTGWQEKNGKKYYLGSDGLSV
                     TGWQEIDGNKYYFDKTGIMQTGWQQIDGKSYYLDKDGKMLTGSQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTANLPTETVEEMKLLAPKTVILIGGENAISSKLEQEIKTTFNTETKRIAGQDR
                     YQTATRIAEELGNREEIKTAYMVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAINDSVIAKMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDTDLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMDNSGLSLEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILAK"
     gene            10973..11836
                     /locus_tag="PC366_002418"
     CDS             10973..11836
                     /locus_tag="PC366_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HDF2577922.1"
                     /translation="MLSSYVKRVSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEY
                     KYAVSQGDYVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDE
                     LPLFLSRLECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARI
                     VIESRDDVSNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIA
                     DILCNPLSRARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPIV
                     EPVGPWLEKMR"
     gene            complement(12044..12925)
                     /locus_tag="PC366_002419"
     CDS             complement(12044..12925)
                     /locus_tag="PC366_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2577923.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYL
                     PPAIKNFKNFVIKNAQL"
     gene            13338..14186
                     /locus_tag="PC366_002420"
     CDS             13338..14186
                     /locus_tag="PC366_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDF2577924.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGTEEDRTEAQREKEQNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTAEDLAPVPADKIVSIQVCDVLETPYEKLRDESLHDRLA
                     PGEGYGNTEEFVKIIKEHNISPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            14265..16187
                     /locus_tag="PC366_002421"
     CDS             14265..16187
                     /locus_tag="PC366_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2577925.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YLERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKVAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEVHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVPGGIDIHDSSVIAAYLEGCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPIACLANPILGHEAELKPAEISKEVLVVGGGVGGML
                     AAWVCAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDVVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHEVTVIELREEVGADVISEHRKFLMNDFENYNIHTITGAKVS
                     KFYDDGVDYLLTDGTEHDLKGFDSVVLAMGSRNYDPLSEVIKEVVKETYIVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            16269..17132
                     /gene="aroE"
                     /locus_tag="PC366_002422"
     CDS             16269..17132
                     /gene="aroE"
                     /locus_tag="PC366_002422"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDF2577926.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFKKLDLDYRYLAFDI
                     TVDKVKEALLAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENGIEVKGKKITIMGAGGAATAIQVQCALDGAREISIFNAKDDF
                     YKRAEQTVENIKKDVPECVVNLYDLEDTNKLYEEIESSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPKKTKMIEDAEANGCKAIGGLGMLLYQGAEAFNLYTGLEM
                     PVEEVNELCFK"
     gene            17332..18549
                     /locus_tag="PC366_002423"
     CDS             17332..18549
                     /locus_tag="PC366_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2577927.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYVFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVVDAILIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLIVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            18785..20650
                     /locus_tag="PC366_002424"
     CDS             18785..20650
                     /locus_tag="PC366_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HDF2577928.1"
                     /translation="MENVFKRLQEFNGYDGYKESFEMNYLCIYESIPLREQVELANNL
                     VDEILNMYKSESNEIYLLEDSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLNVENLREVVDTFSKSGEYVFYLSNTIKKLEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEDGYKDTKYERLLMNYIISIVDLNEYLE
                     KRDLDKEKINNLARLICNYLLSVEFKYIGNKLELVNRFLPTVVNYGTNFESLYSIFLI
                     AINVLKDENIEYNKIEFEKEINDILLSEKWKNIYFEALRDASGKTEDIIKMSEIYDVN
                     LSFDDLLPYLNRDIRDFEVYWHISKKGTTSSRLKLLNFFEETFKIDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKIVKEAYEKEKNVILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSIAV
                     AGSRFRNREYLEKELEKSKIYYLTREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(20828..22192)
                     /locus_tag="PC366_002425"
     CDS             complement(20828..22192)
                     /locus_tag="PC366_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2577929.1"
                     /translation="MSQLLIKNAYLITMNADREVYETGSILIENNIIKNVGKFDINIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLIRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEIDLFRLHDVK
                     VSHNPGAAMKVVLGFASIPEMLEKGIPVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKKQASKIKDKAEVKIPSKF
                     KIIK"
     gene            complement(22339..23682)
                     /locus_tag="PC366_002426"
     CDS             complement(22339..23682)
                     /locus_tag="PC366_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDF2577930.1"
                     /translation="MVPNTNNVQPDGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     regulatory      complement(23755..23856)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            24186..24839
                     /locus_tag="PC366_002427"
     CDS             24186..24839
                     /locus_tag="PC366_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDF2577931.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVVFENCNLSNSFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKDVLGKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNLKKANFNGTKLSGIDFTTNNIEGIEIGIDEIRGAIFDVSQAIDLTKLMGIIIK"
     gene            24980..26251
                     /gene="brnQ"
                     /locus_tag="PC366_002428"
     CDS             24980..26251
                     /gene="brnQ"
                     /locus_tag="PC366_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDF2577932.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAIFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            26453..27640
                     /locus_tag="PC366_002429"
     CDS             26453..27640
                     /locus_tag="PC366_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HDF2577933.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKIIDDFKVAVVTQ
                     PLSENKVQYNMVEEMTKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISEKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSVAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
BASE COUNT        10868 a         3109 c         4833 g         8948 t
ORIGIN      
        1 taacttttaa aaattagttt tactaattta caatagaata ggtgtgctgg tgtggctcaa
       61 cggtagagca gctgacttgt aatcagcagg ttgtaggttc gattcctatc accagctcca
      121 gtaaagacta tgtttttagc atagtctttt tttattgttt tttattgttt gatgtatttg
      181 ttattttgta ttacatactt ttagtggcct aatttataaa ttataggtat aaaagatgac
      241 acagtttaaa attattgttt taaactgtgt ctgtgagttt taaatcaatc taccatgaat
      301 caccattctg gcatcatcaa attcataggt acatgtagaa agtgtaacta ttttatcatt
      361 gctatttacc ttaataggag atttatacaa tgatttagaa gtaatatcat ttatgtaatt
      421 ttgataatca gattcattgt taaaatttgt ttttagataa tcataatcag attctacaat
      481 ataagcagaa aaaacatcat ataaaaattc ttttccattc aaggttattt ttattttatt
      541 attgttttta aagaagtcag catctttaaa cttatttagg ttgttgaaca tagttttatt
      601 tttcatatta tgtccatata ttatgatatt tttgtcatca atagatttat ttctataatc
      661 cataaacagt gtaccagaaa tagaatcttt tttataaaaa tctttgtcaa gatagtaaga
      721 attatcttta gattgtacaa ctggataatt tatatttgta ttctcaacag aaagccaaaa
      781 tttaaaatca ctgttaatct ttgataaatc ctctttttta tattcttttt tttgaagttc
      841 tgaggatgtt ttagtatcat gattgtattt ggtaagtttt gagtatatat taaatccact
      901 gtaaagtatt actaatacta gtataatgtt aattactatt ctatataatt ttttcaatat
      961 atcacctcga gttaaatgga gtttatatat ctatattaca ctatttttga ataaatttaa
     1021 atttttagta taatattact ttgacatgta aaagaatttg tgttaacata actaagtaaa
     1081 ataaatatta agtaagccag ataatcgcat gtaatcttac atgaggaaag tcggagctcc
     1141 atagagcagg gtgctaggta acgcctagtg ggagcgatcc taaggatagt gcaacagaaa
     1201 taaaccgcca ctattgtggt aaggatggaa aggcgaggta agagctcacc agcagctagg
     1261 cgactagttg gctatgtaaa ccccacctgg agcaagacca agataggaat aaagagtgct
     1321 gctcgtactc tccggtaggt aggtcgcttg agcctattgg tgacaatagg cctagaaaga
     1381 tgattatcta atacagaact ccgcttatag acttgcttaa ttatttcgat agtcaaaaac
     1441 atcagtttaa actgatgttt ttttatttgt aaatttgtct aatctacttt taaaattttg
     1501 aggaatattg taatataagt tagtacagat attaaaaatg gtataatata agatagatat
     1561 aaaaagaaaa agtaaaatga tgtaaataat atgatatgat ataagatgta gcaaatttag
     1621 taaataatta tttagatatc ataatcaaat tagcaacttt gcacaatgta aatattacaa
     1681 taaaataatt gatttaagga gtgaaggttt tgagtgaaaa taatataata agaaacactg
     1741 ttttaaatgt cacagcaagt tttttaaaac aagagtctaa aataaatgaa aagctagatg
     1801 gtgttttgga aaagaaattt gaaaaagtag aatttaatga agcaaaatat gcagagcttt
     1861 taaaatttaa tatattgttt tataagacat tagcaagaaa tacagaacca cttattggca
     1921 aatggatagt agataagtac atacctgaaa tagatgaatt agaaaaagat ttagaattaa
     1981 ctacagcaaa atgtagaaag tatgtaaata aggctatgaa agagggatta gactctctaa
     2041 aagccaatga tttaaatagt tttttagctt atgataaaat ggaactatca gagagaagaa
     2101 gacgtttaga aaaggattat aaggttttaa acctatataa agacctcctt aatatatctc
     2161 ttagaaaaat aagtttagaa aagaaagaat gtggagattt atttcttaaa aatcaagcag
     2221 atgcgaaaag agaattaaaa agagaaatta tattctgtgt aaacaaaata ttagctagca
     2281 ataaagatgt ggtacctaat aatgtggaag agaataacga acaagacaaa gtagaaataa
     2341 aagcaactga aattgaggat ttgcaattag gtaaagataa ttcagaaaat gacatgctac
     2401 taaatgaaat taaaaattca aaagtaaaac atgaatcaaa atcaaatgat atagaatcga
     2461 agtttataga taagttaaat agcttaaata atgaaagtat atctcaaaca atacacaatg
     2521 aatataagaa gttatgtgga ttagaagaac ttcattctgt tgaaggatat ggttttggca
     2581 aagaaattat taaagatttt gcttgtgcaa cggttgtatt agaattttta aagagaagaa
     2641 atagagacct tatagaaggt gcaatgagac tgactataat tggagaattt ggtcctgaaa
     2701 attttaagga atttgtggac tatgtaatta aaaataaaac agaaattagt gaagatacat
     2761 ggaataaagc acagaatcta ataaaagata actatagtga attagaaaat catgaaattg
     2821 catcaaaaag aactagaaga aataaagata tcgatattga agaatacatt tacatgataa
     2881 aaaatgcaga taaagatatt tgctttagaa gtagtatttc aatagaagat gatgctgaag
     2941 aaggggctaa agaagaagta gatagtaata atcaagatat aggtgacgtt gtagaagata
     3001 aagatactac agataaagag tacgacagca ataaagaaga tataattgaa ccagaaaata
     3061 aaaagagtaa aaagaaggct aaattatttg gatttattaa aaaagacaat gaagaagttg
     3121 aacaagaaga agagaattta aatgatattt ctcctgatat aattttagat aaaccagttg
     3181 aaaatcatca agcaaaatca gaagaaatag agcaaaatga attaaaagaa ataaaacaag
     3241 aagaaccaag tcaacatata gaagaagaac gtagtgtaaa aatagaaaaa ccaataaata
     3301 ataacttaga tgaaaaagta tcttcaaata atgaatcgaa gcttgaaaaa gaaagtaaaa
     3361 acttagaaga taaaaaagca aaagaaataa aagaagaaaa attagaaaat gaaaaatcag
     3421 tagtaatacc tattaaaaag aaagaaaata gtaataaaaa atctaaaaat tcttctaagg
     3481 acaaatatag agaaaacaag aaagaaatga aaaattatgt atcagataaa gaagattctt
     3541 tagatgatga agaggttgtt tctaagaaga gtagattaaa agaaactatt atagcagtag
     3601 ttatagtggt tattgttggt gtaggatatt ttataacagt aggcaacaat aagaaaaatg
     3661 ataaagagaa tattccaaag tcatcaactc aacaacaagc taacaataaa ttaactgagg
     3721 aagagaaaaa agcacaagct gaaaaagaga aaaaagaagc agaagaaaag gcaaaagctg
     3781 aaaaagaggc tcaagaaaaa gcacaagctg aaaagaaagc aaaagaaatg gaagcatata
     3841 aagatggtaa aggtgtatat tacactgttt atgcaggttc acttaaagtt gaaaaaacag
     3901 caaaagaaac agcaaaagaa tatgaggcta aaggtatttc ttcaacaata attcaagaaa
     3961 atggatacta taaaataaaa ataggtgatt attctcaata tggagaagca caagaaaaat
     4021 gtaatgaact agctaagaaa tctattgata catatatagc tatgtatgat aagtactatg
     4081 attataagtt agaagaatta aaagaatcag ctccttcttt gagtgctgaa gaacttaaac
     4141 aaaaatatga agatttaaga agtgagttaa agaacaaatc tggatatcgt gaatatgtta
     4201 aacatttaga taaactttat gaagaaatag ttgaaggtgc ttagagcatt ataaaaaagg
     4261 agaaactatg tctcagaata aaaagtatta aaaaaatatt atttgttttg agacatttta
     4321 ttcaccttta taaaatactt ataattctgt ttaggtggtg aaggtatgtt gaaattagga
     4381 gaaaaaatca tatatgagct ttctgatggg tttgagctta gtggcataag tagatactca
     4441 aaagaatata aaaagcttca tataacaaat ctagggaata taataatcag caaatcagat
     4501 gaagttaatg aggatacagg tgtaaaatat atatatagtt tttcagacaa taaagaaaaa
     4561 ttagaggcag ttttagaaga ttctcaaata attgtctatg gaaataactt gcctttttac
     4621 ataaaaagtg aaaattcaag taaaaatgtt acagcaaatt tgactatgaa aataactttg
     4681 gatgaatatg atttaatctg caaaagtcaa agagaattta tattctatct aaaggataat
     4741 atgactatat taagtttaga tgacaataag ttttatatgg gtggaattaa taaagataat
     4801 gagaagttta tatttatcag tgggaaaaat agatttgaaa taaattttga tgatatagaa
     4861 agatacattt tagaagataa aagagtgtca ttgaagggat actttcatat ggaaagagag
     4921 gggattatag taaggtctgt atctatattt aataacaata tagatagtgt agttccatct
     4981 gatttaaatg agagagttaa agataaccaa aaaataggaa atcttcctaa agattgtgat
     5041 atagtattct gcaagatatc aggaaatata gatggatttg attataaaaa cacaaacatg
     5101 cttttagtaa aatatcaaga ccaattaatt tttataaata agaaatctaa gaagactatt
     5161 gtaaagtcag cgaaagataa ttgttctaag ttaaatttag gagaagatat aatattatat
     5221 gataataaaa atgtatttaa cctacatata aatgataaaa atagagaaat tatgcaaata
     5281 gatgacttaa aagatataga aaatgaaata gtgggatata cattaaaaca tgctccattt
     5341 tttattcaag aagatttcga tagcttgact attctaaagt cttttcaaaa agaaatcata
     5401 tctataaaaa atagtgatat aaaagacatt gtaattaata aagaacttga aaacgaaaat
     5461 tctaattttg tagaaacgga aataaaattt aataatcaaa aagtactttt aaacttaagt
     5521 aaaaatatgg ttcaaaaact tatgcaagat gtatttatat atgcaaagca acctctactt
     5581 aaagaaaatt ctattgaagt gatatataag aattggtcta aagctatgaa tgatatgata
     5641 atatttaatt tttttggaaa tatttactat atgaaatctg aatttgataa gattttagaa
     5701 aaagagttaa atgatgaaat aagaatagaa gttataaatt cactttataa gcaaatacaa
     5761 gaacaaagaa acaatttaga tttattgtca gcatatatgc caagaatatt agaaaatcaa
     5821 gaaatagatt tgtttgaaaa gtataatact aaacttgatg tacaagtgtt taagcagatt
     5881 aaaaatctat tgtctgactt atcatataat ataagcagtt atttaaatga agttgaaaaa
     5941 agtttagaca atatcatctt tgtaatttca ggagaagata agaagaaata caattataga
     6001 atgttaaaag aaagtgaaag tgcaagtctt gatgtatttt taaaacaagc catatcaaga
     6061 ttaaaccatt tagtagaaaa tatgtatcct tattatgtag atgaaactag tagggaaatg
     6121 tttaagttat ttgagttatt gtggaaaaac tatagaaata ttgatgatga tagtataaaa
     6181 gaaatattat tcgagagaat aacaaataca tatgtattta aacaattgac attaaataat
     6241 agtacaaaag aaagaagaaa agacataatt gaaaaaatat ataactctgt tgattatgga
     6301 accaataaac tagatgaaaa tatgtttttc acaggaggaa taaagtatgt caagtaaata
     6361 caatgtttgg acttttaact atgagttctt aggattggac tcaggggatg aaaaaaataa
     6421 tgaagtttat tacgagattg atttagatga aattttaaat gaaaactata tagatgaaga
     6481 tatagatagt ggtttagatt ctgatggaaa tagtatttta ggagaattaa tatcagaaat
     6541 ggatatagat gaggatgtca gtgttgatat gacatatcaa gaactagaag ttgacttaga
     6601 agatttagat tcttatctag atgaagatat agatagtgat ataaaaggca tcttagatga
     6661 aatttagtac ctgtataagt tttggataaa atataaacaa tacaatatta acttataaaa
     6721 ctaaaggtag atgaaatttc atctacctta tattatctta tagcattaaa tattgggata
     6781 atatagagtt tgaagaaaaa gtataaatat ggtatattaa tttggtacaa tagaaaattt
     6841 acgaagaagg gtgaaaaaat gcagatgaca gttaaaaaag caataatacc agcagcaggg
     6901 ctaggaacca gatttttacc agcaacaaaa tcacagccca aagaaatgct tcctatagta
     6961 gataaaccaa ctttacagta tataatagaa gaagctatag aatcgggaat tgaagaaatt
     7021 cttataataa caggtagaaa taaaaaatct atagaagatc attttgataa atcagttgaa
     7081 ttagagttag aactagagca aaaaggtaag acagagatgt tagaaatggt aagagacata
     7141 tcaaatatgg taaatattca ttatataaga caaaaagagc caaaaggtct tggacatgca
     7201 atttactgtg caaaaagttt tataggtgat gaaccttttg ccgtattatt aggtgatgat
     7261 atagtagatt cagatgttcc gtgcttaaaa caattaatag atacttataa tgagtataaa
     7321 acaactgtat taggtgttca aaagatagct aaagaagata ctaataaata tggtatattg
     7381 gatgtaaaac atatcgaaga tagagtatat aaagttaaag atatggttga aaaacctgca
     7441 attgaagaag ctccatctga tatagctata cttggaagat atataataac tcctgcaata
     7501 tttagtatat tagagaaaca gacacctggt aaaggtggag agatacaact gacagatgca
     7561 cttcaaactc ttggaaaaca agaggctatt tatgcttata actttgaagg tagaagatat
     7621 gatgtgggag ataagattgg ttttttagag gcaacaatag actttgctct aaagagagaa
     7681 aatttaaaag atgatttaat ggactatatg agaaaaaaag taagtgaaaa ataaaatatt
     7741 agaaaagagg taattacaat ggcagtttta gtagctggag gagcaggata tataggaagc
     7801 catacagcaa tagaactttt agaatcaggt tatgaagttg ttatagttga taacttaagt
     7861 aatagcaact caatagtggt tgatagaatt aaggaattat ctaaaaaacc agtaaaattt
     7921 tataatattg atatcagaaa taaagatgaa atgcatgttg tatttaaaga aaataatatt
     7981 gaatcaatta tacactttgc agctttaaaa gcagttggtg aatcagtaga aaaaccaatt
     8041 gaatattaca gcaataatct aataagtacc ttaaatttat ttgaattaat gagagaatat
     8101 ggtgttaaaa agtttgtatt tagttcttca gctactgtat atggagaccc acatacttgt
     8161 cctatattag aggatttccc actttctgta accaatccat atggaagaac taaacttatg
     8221 atagagcaga tgttagtaga tatatcaaaa gcagataagt cattggatat agctctttta
     8281 agatacttta atccagttgg tgctcataaa agtggtagaa taggtgaaga accaaatgga
     8341 gttccgagca atctaatgcc ttatataaca aaaatagcag taggtaaatt gaaggaattg
     8401 agtgtttatg gtaatgatta tccaacacat gatggaactg gagttagaga ctatatacat
     8461 gtattagatt tagctgctgg tcatgtaaaa gcattacaaa aattagaaga aaatccagga
     8521 cttgttgttt ataatttagg aactggaaag ggttatagtg ttcttgattt agtaaaagca
     8581 ttttctaaag caagtggaaa agaaatacca tataagattg taggaagaag ggctggagat
     8641 gtagccatgt gttatgcaga ttcttcaaag gcagaaaaag agcttggatg gaaagctaag
     8701 tatgaacttg aagagatgtg tgaagattca tggagatggc aaagtatgaa tcctaatggg
     8761 tatgaagagt agaatacata cttatatgta taaatgtaac aaatttgtaa atataaggta
     8821 ttggtaattt tatgttataa ttagacacat gtagtaatgt ttctaaaaga gggggaagtt
     8881 atagtgaaaa aaagtctaaa aaagtattta gtactagcac tgactttagt tttagtattt
     8941 gcatgtggcg taccagaatc aagcgcagcc agtaaacatg tgattatagt aaattcaaga
     9001 aagaatactc taggatattt tgtaaataat aaacttgtaa aagaatttag agttgcaaca
     9061 ggtaaaaagg ggtcagaaac accaacaggg aaaacaaaag tagttaacaa gataaaaaat
     9121 agaccatatt ataaaggtaa tatacctgga ggaagtccaa gaaatccatt aggagataga
     9181 tggatgggat tagcattaaa aggaacttat ggagatacat atggaataca tggaaataat
     9241 aatgagagtt ctataggaaa gcatatttct ggtggatgta taagaatgca caataaagat
     9301 gttagatggt tatttgacca agttcctgta ggttcagatg taattataga ttatagtaat
     9361 gacagctatg taaagatagc ggcaaaatat aagataaatc taaatcaaac aggatggaaa
     9421 acagaaaatg gtaagaagta ttatgtaaaa tctgatggaa cataccaaaa gaatagttgg
     9481 ctaaaagtaa atggaaaaat gtattacttt gatgcttcag gagtaatgca aacaggatgg
     9541 aaagcaatta ataacaaaaa atattattta ggaactgatg gagcaagagt atctggatgg
     9601 aaagtaatag acggaaaaac ttattacttt aactcagatg gagtaatgca aacaggatgg
     9661 caagaaaaga atggaaagaa atactatcta ggatctgatg gtttatcagt aacaggatgg
     9721 caagaaatag atggtaataa gtattacttt gacaaaacag gaataatgca gacaggatgg
     9781 caacaaatag atggtaagtc ttactattta gacaaagatg gaaagatgct aactggttct
     9841 caaaaaatag atgggaaaga ttatactttt aatgaagatg gaactataaa tcctacatgg
     9901 gatacaatta taggtgcaaa tagatttgat acagctaaaa agataagttc agttggaaac
     9961 tggaatgctg atagttcaga tactgtaata ttagtaaatg gtaatgcaat agctgatggt
    10021 ataacagcaa ctcctttagc aagtagctat gactcaacaa tactacttac taatacagct
    10081 aatttaccaa ctgaaactgt tgaagaaatg aagttattag cacctaaaac agtaatcttg
    10141 ataggtggag aaaatgcaat aagttctaaa ttagagcaag aaataaaaac tactttcaac
    10201 acagagacaa agagaatagc aggtcaagat agatatcaaa ctgctacaag aatagctgaa
    10261 gaacttggaa atcgagaaga aataaaaact gcatatatgg tttctggaaa tggggaagca
    10321 gatgctttat ctgtagcttc taaagctggg gaagaaaaac aacctataat attagtcaat
    10381 aaagatggaa ttacagaaga atcttataaa tggctaacag aaagaaaatt agaaaatgca
    10441 tactttatag gtggaccaag tgcaattaac gattcagtaa tagcaaaaat gaatgatata
    10501 actactgaag atatttcagg aaatagaata tatggagata gtagagtaga tactaatgcc
    10561 aaagtaatag aaaaattcta tggagatact gatttacagg ctgtattagt tagtaaatca
    10621 gatgctttag tagatgcttt atcagctgga ccattagctg taaaattaca ttcaccaata
    10681 gttttaatgg ataattcagg attatcatta gagcaacaaa gagtatttgc aaataaaaaa
    10741 gttgaaactc cttatcaaat aggaggcgga gtatcttata tagtaatgga taaattaatg
    10801 gatattcttg caaaatagta aaaatatata ttgaaaaata attataattg agatgtgaaa
    10861 ttcaatcaat aaaagcttga ttgttttaca tctcaatttt ttagtataaa attaagttta
    10921 agttatataa aaatcttgga atatttttaa aactcatata aaatgaatat agatgctatc
    10981 atcatatgtt aagagggtga gtaagattat aaagaaaaaa tatataatgt ttattgatga
    11041 aagtggaaga gctgatataa atcatgaaga cccatttaca ttgacaggag taatttttga
    11101 atataaatat gcagtaagtc aaggcgatta tgtatgttct ttgaggaaag aaatggatgc
    11161 atttaaagag tattgttttg gaaccagtaa cataggaata catttgacag atatatcaag
    11221 aaaatcaaga gcatttgaga agtttgatga ttcacagatt aagttattct atgatgagtt
    11281 gcctttattt ctatctagat tagagtgtac tataatatca gtaacagtag ataaagctag
    11341 attaaagaaa tattatgcac cttcaaagga accgtatgtt gtggctttta tacatgttct
    11401 tcagaatttt tattcatttg taaataatga aactgtagaa tctgcacgaa tagttataga
    11461 gtcaagggat gatgtctcaa acttaaaagt acaaaaggcg ttttttgatg tatttaataa
    11521 tggaacaata tacttagata tagatgaaga attaagagat aaggttaagg gttttataat
    11581 tgccaaaaaa gaagatgctg actatagaga aggtttagaa atagcagata ttttatgtaa
    11641 tcctcttagc agagcaagaa gagggttaat agaagctaat ccaaagtgta tgcaatatgg
    11701 agaaaaaaac aaaatattca aatctgtcag aaacaaaata tatactccaa cgagtgtgaa
    11761 tgatataaga aattggggat ttaaagaagt tcctattgta gagcctgttg gaccatggct
    11821 tgaaaaaatg cgttagatac aattgacaaa tttaaaaaaa tctgatataa tgtaaataac
    11881 ctagttattc aggaactgaa tccagttgct gttgtataac gataattact gagactcgga
    11941 tgccgactgt cagttaggaa tctatacttt taaaagtata gattttttta ttttataaaa
    12001 agaataaaag aggatattta aaaataaccc ctttattaat aaattataat tgagcgtttt
    12061 taatgacaaa gtttttaaag tttttaattg caggaggcaa atatctatct tttataaatg
    12121 ctaagtaaaa gtttctttcc caacttgggt gaataatctg aattactttt acttttgtaa
    12181 agctaagcat attcatattt gggactacag caattccgaa attttttgca actaatccag
    12241 caattacttg gtcttcctct acttcataga ctatattagg ctgttgattt atttttttaa
    12301 acatatcatc aattatatat ctaagaccac ttctctgatt aaatactatt tgaggataag
    12361 gtatggtttc ttttaaatct atagtatcct ttgcagctag tggatgacta tatggtacaa
    12421 ttagtactaa atcttgtttg gcaacaggta taaattcaat tcccttttct ttttcaagtt
    12481 tcgaacaaaa tgcaatatca tattttcttt ctttaagacc ttgaataatg tcagtagtta
    12541 caccagtatg aaatttaaaa tctattgatt tagcaggatt agattttaaa aatttatgca
    12601 ctatgtctgg gataaaatca gtaccaagtg ttctaagaaa agctaagtct atttgtcctt
    12661 caccagtacc agttattttt aatgatttta cacttgaatc taaaatttct aatgattttt
    12721 ccacatcttt taaaaatatt tttccatact tagtaaggac tatatttcta ccttcttttt
    12781 caaatagagc caccccaagt tcattttcta gtaaagaaat agcatgactt aagcttggtt
    12841 gtgttataga taaattttct gccgcttttg tatagtgttc taaatgtgcc aatgtaacaa
    12901 aatagcgtaa gtgatataaa ttcaattttt gttcatcctt tcataggtat ttttatttat
    12961 atatttgtag aagttaacct ttaagatatt tttacatttt tattatatat gattatagag
    13021 taagaataaa agcttttaaa aaaatttatc gttttttgtc tgaattataa gataaatata
    13081 tttatacaac ctaatagaaa aatacaagaa ttatcttata aataaaatct ataaacaaaa
    13141 tctatgaatt aataggaaat tatcaatttg ttattagtaa agtctcgtga tacaataaat
    13201 ttataaaatc tagataaata gaaatcaaaa aatactttta tttttaaggt aaaataatac
    13261 tactagtagg ataaataaaa atataaaatc aaagatacta ttaattataa agaaaataaa
    13321 gggggcaaat ttaagctatg aataatcaaa aaaatcttaa tattccaatt acaattagtt
    13381 cttatacatt gggaacagaa gtttcattcc gtgatagagt tcgtattgca aaagaagctg
    13441 gatttgatgg tattggattg cgtgctgaaa attatattga tgcaaaaaat gcaggtgtta
    13501 cagatgaaga aatgattgca attcttaatg aatatgatat gaaagttaca gaagtagaat
    13561 atataactca atggggaaca gaagaagata gaactgaagc tcaaagagaa aaagagcaaa
    13621 atgtttatca tatggctcac ttatttaatg ttaaacatat aaattgtgga ttattagaga
    13681 tgataccaga agaacaaatt ataactgcat tgggagaatt atgtgacaga gcaggtgaac
    13741 ttattatagg tcttgagttt atgccatata gtggtgtacc agatttggct actgcatggc
    13801 gtgttgtgaa aggatgtaat cgtgaaaatg caatgcttat attagatact tggcactggg
    13861 ctagagcaaa gcagacagca gaggaccttg cacctgttcc agcagataag atagtatcaa
    13921 ttcaagtgtg tgatgtttta gaaactcctt atgaaaaact tagggatgaa tcactacatg
    13981 accgtttggc tccaggtgaa ggatatggaa acacagagga atttgtgaaa ataataaaag
    14041 aacacaatat atcaccaaga gtcatagggg cagaagtaat atctgattct ctaatatcta
    14101 aagggttatc cactgctgct gaaactgtat ttaatgcaac taaaaaagtt ttggataaag
    14161 catggtctga agtatctcca aaataaactt atataatata aaaatataca gagtattata
    14221 atataaaact tttaaatata aaacttgaaa ggaaggaaaa ccttatgaag attagttcta
    14281 tgtttacacc tataagaatt ggttcaatga cagttccaaa tcgttttgta gttcccccta
    14341 tgggaaacaa ttttgcaaac acagacggta ctttaagtga aacttctaag gcttattatc
    14401 ttgagcgtgc tttaggtggt tttggattaa taactataga atctagtgtt gtagacaaaa
    14461 aagcaaaagg aggtcctcgt aagccttgtt tatatgatga tagcacaata gatagtttta
    14521 aaaatgtaat agatgcttgt catgatgcag gttcgaaggt atctatacaa ttacaacatg
    14581 ctggttctga aggaaatgaa aaagtagcag gacatccatt aaaagctgct tctgcaatac
    14641 ctgcatcaaa tggtcgtaat acaccactag caataacaac agaagaaata tatgaactta
    14701 tagaatctta tggagatgct gcattacgtg cacaaaaagc tggtgcagat gctgttgaag
    14761 ttcactgcgc tcatggatat ctggttagta gttttatatc acaaagaaca aataagcgtg
    14821 tagatgagtt tggtggatgt tttgaaaata gaatgagatt acctcgtctt atcattgaaa
    14881 atatacgtaa aaaagtagga aattctctag caatattatg tcgtataaac agcactgatg
    14941 atgttccagg aggaattgat atacatgata gttcagtaat agcagcatat ctagaaggtt
    15001 gtggaataga tggacttcat gtttcacgta gtatacatat acatgatgaa tatatgtggg
    15061 ctcctacgac tttacatgct ggattcagtg cagaattagt tactgaaata aaaaaagctg
    15121 ttagtatacc agtaataaca gttggacgtt atacagagcc acagtttgct gagttaatgg
    15181 tcagacaagg aagatgtgat ttagtagcat tcggtagaca aagcttggct gacccagaaa
    15241 tgcctaataa agctaaaaat ggaaaactag acgaaatgat accatgtatt gcatgcttac
    15301 aaggatgtgt accaaatatg ttccaaggaa aacctatagc ctgtcttgca aatcctatat
    15361 taggacatga agcagagctt aagccagctg aaattagcaa agaagttctt gttgttggtg
    15421 gaggtgttgg aggtatgctt gcagcatggg tatgtgctaa aagaggacat aatgtaactt
    15481 tagttgaaaa atctgaagtt cttggtgggc aaatgcgttt agctgcatat cctccaggga
    15541 aaggagatat tactaactta gttagaagtt atatttcaaa atgtaatcaa tatggtgtaa
    15601 aaatatgtac taatacagaa gctacagtag aacttataaa ggagaaatca cctgatgtag
    15661 ttattatagc tactggagca actccacttg tacttcctat accaggaatc aatgattcag
    15721 gattaattca tgctgtagac cttcttgatg gtaaaaaatc ttgtgggaaa aaagtacttg
    15781 ttgttggagg tggaatggtt ggatgtgaag tggcagcctt ccttggagaa caagaacatg
    15841 aggttactgt tattgagctt agagaagaag ttggtgcaga tgtaatttca gaacaccgta
    15901 aattccttat gaatgatttt gaaaattata atatacatac cattactggt gcaaaagttt
    15961 ctaaatttta tgatgatggt gtcgactatt tacttacaga tggcacagag catgatttaa
    16021 aaggttttga ttcagtagta cttgctatgg gttctcgtaa ttacgaccca ttaagtgaag
    16081 ttataaaaga agttgtaaaa gaaacttata ttgttggtga tgcagtaaaa gctcgtaggg
    16141 cattagatgc aacaaaagaa gcttttgaag tagcattaaa tatataaata ataaataaat
    16201 ttttctttgt aaataactga ataggttatt tgcaaagaaa atgataatat tgggaggaaa
    16261 ttatagttat ggaaatttca ggtagaacag gattatttgc attaataggt acaccagttg
    16321 gtcactctaa atcaccagtg atgtataatt atagttttaa gaaattagat ttagattata
    16381 gatatttagc ctttgatatc acagtagata aggtaaaaga ggcactttta gcaataaaaa
    16441 cttttaatat aaaaggagcc aatgttacta tgccatgtaa atctgctgtt acagaatata
    16501 tggatgaact ttctccagca gctcgtataa ttggagcatg taatacaatt gtaaatgaca
    16561 atggaaagtt agttggtcat ataacagatg gagtaggcta tgttcgtaat ttaaaagaaa
    16621 atgggataga agttaaaggt aaaaagatta caattatggg tgctggtggt gcagcaactg
    16681 ctatacaagt acaatgtgct ttagatggag caagagaaat atctatcttt aatgctaagg
    16741 atgattttta taaaagagca gagcagacag ttgagaatat aaaaaaagat gtaccagaat
    16801 gtgttgttaa tctatatgat ttagaagata caaacaaact ttatgaggag atagaatcaa
    16861 gtgatatatt gacaaatgca actcttattg gtatgaagcc ttatgacaat gaaacaaata
    16921 taaaagatac tagtgtttta agaaaagact tagtagtaac agatgtcgtt tataatccta
    16981 agaaaacaaa aatgattgaa gatgctgaag ctaatggatg taaggctatt ggtggattag
    17041 gaatgttatt ataccaagga gcagaagctt ttaatctata tactggatta gaaatgcctg
    17101 tagaagaagt taatgaatta tgctttaaat agataagagt gatatcttaa acaatgaaaa
    17161 aacatacgta tttcaatatt tttaataata aattacaaat tgtcatagtg ggttttgcat
    17221 catagtccag ttaaatttga agctttaact gactatactt taaatccatt atgaggatga
    17281 gtttattgta cacaaaaatg ttaataaatt aacaagaatg ggagaaaaat tatgaacaat
    17341 aaaaaatatt atcctactgc catagcgttg tatttttcat attttttact tggtattgga
    17401 atttcaattt taggacaata caaaccagaa ttttcatcaa tgtggggggc taaaacacta
    17461 tcagatggaa cattggatgt aagtattgtt ttagctgtta ttgctgcact aggattaggg
    17521 agacttatat cttatccatt tgcaggacct atttcagata agtatggaag aaaagtaagt
    17581 ggtcttatag gaaactttct acatgcaatt ttctttgttg gaattgtatt ttcaccaaat
    17641 ttttatatag catatgtatt tgcaataatt ggaggggcag caaattcatt cttagatacc
    17701 tgtgtaactc cttcttgtat ggagatattt gctagtttag gaacaatagc aaatatgttt
    17761 actaaattta caatagcttt agcacaattt ttgcttcctt ttataattgg atttgttgca
    17821 gcaaattcaa tatcatttaa agttattttt atagtaacag cgattcttat tgtagtagat
    17881 gccattttga tagctgtgtt accatttcca ccagctaata atgttattga taacaaaggc
    17941 aaaacagtta aatcagagaa gatgaaattt acaccaacaa gtatagctct tgtttgtatt
    18001 ggatttacat gtacatctac atttgtatta tggttaaatt gtaatcagga attgggtaaa
    18061 ttgtatggga tggctgaccc tacaaaaatt caatcctttt actcaatggg agtaatatgt
    18121 gcagtattaa taacttcttt acttattaaa aaatatatta aaccaataag aatattagtt
    18181 atatatccta taatagcttt acttatgcta ttaattgtat attttgttca aactccaact
    18241 atttgtatgt tagggggatt tgtaataggt tattcagcag caggaggtgt tcttcagtta
    18301 acaacgtcaa ctgcaaatga aatgtttcca actaataaag gaaaaataac atctatagtt
    18361 atgattgcat ctagtatagc aaactatgtt attttaaata tagcaggtat tattacaaaa
    18421 tcagggggag ttaatggacc aaaatatgtt gtattgttta atgtggcaat aacatttgtt
    18481 ggaattttac ttgcattgtt tgtaaacatg agatatgaaa aagaaaaagt gtatgattat
    18541 gatgtctaat attagtataa tatatgcata gagaagtcta aatctaggat agatttttat
    18601 taaaagtaat taaaattaat aaggatatta tttacagtta taagataggg tatttacata
    18661 attaataata aggatattac tagaatttca atttctagta atattttttt gcgtataaat
    18721 gtaaacttga cgaaataagt agtataatca atataaatta catcatgtaa aggaggataa
    18781 tttggtggag aatgttttta agcgattgca ggaatttaat ggttatgatg gatacaaaga
    18841 atcatttgaa atgaattacc tatgtatata tgaaagtata ccgttaagag aacaagtaga
    18901 acttgcaaat aatctagtag atgaaatttt aaatatgtat aaaagtgaat ctaatgaaat
    18961 ttatttattg gaggatagta attctaagtc tttaatttgt tatttcgaaa tttttatgaa
    19021 aaagataaat actttggtaa aagaaatgat tattgatgag aaatggttat ataaattaac
    19081 taaagaatta atatataaga gtaaaaaagt tgagtatgta aaactagggt tagttttaag
    19141 tgagaaatat ctaaatgtag aaaacttaag agaagttgta gatacatttt ctaaatctgg
    19201 agaatacgta ttttatctga gtaatactat taaaaaactt gaattttaca atacatattt
    19261 atttaattta tctaaaaagg ctacaggttc aataaaagta tttgctattg ttaatatgga
    19321 aaatttagat tctaaaataa attcctatct aattgaagat ggttataagg atacaaagta
    19381 cgaacgatta ttgatgaact atattatttc aattgtagat ttgaatgaat atcttgaaaa
    19441 acgagattta gataaagaaa agataaataa tttagcacgt cttatatgca attacttgct
    19501 aagtgtagaa tttaaatata taggtaataa attagaatta gtgaatcgat ttttacctac
    19561 tgtagtaaat tatgggacta actttgaaag tttatattca attttcctaa tagctataaa
    19621 cgtcttaaaa gatgaaaata tagagtacaa taagattgaa tttgaaaaag aaataaatga
    19681 tatcttgctc agtgaaaaat ggaaaaatat atattttgaa gcattaagag atgctagtgg
    19741 aaaaacagaa gatattataa aaatgtcaga aatttatgat gtaaacttat cttttgatga
    19801 cttgttgcca tatctgaata gagatattag agattttgag gtatattggc atatatctaa
    19861 aaagggaacg acaagttcta gattaaaatt attaaatttt tttgaagaga cgtttaaaat
    19921 agatgattta attggaaaaa tgaaagatat agaaaaagat aaattgactc aagaatatta
    19981 tgatgatatg ttatttttta ttgtgcttaa aggaagtaaa tcactatatc ctgaaggaaa
    20041 gaatatatct ttaaaaggaa tatttggaaa tataaatgaa gtaagaaaag aatccataaa
    20101 tatcttaaaa agatacagag agaaactatc tcttgaagaa ttaaaaattg ttaaagaagc
    20161 gtatgaaaaa gaaaaaaatg ttatattgaa ggatgaatta agaagagtat tatatgaaag
    20221 taataattta aaaaaagaat ttgtaaatat tgaaaaaata aaagtagatg aacatggtaa
    20281 ggatatctat ttgacttcaa tagctgttgc tggttcaagg tttagaaata gagaatatct
    20341 tgaaaaagaa ttggagaaga gtaagatata ctatttaact agagagaaag ataatctata
    20401 tgatgaaaaa gctattaaaa tagttggtga aactggatat gtaataggct atgtcccaag
    20461 aaaagaaaac tatattttga gcaatttatt agatggagga aaactgctgt attgtagagt
    20521 aactgaatat aatttatatg aagattgtat ctacgcaaat gtgtacttga gttataaaga
    20581 tgtaattgaa acagttgaaa actctttaaa gatggtttta gataagagta gaataaaact
    20641 tataaactaa gacgtttata tattgcttag atgatgtaat cctaactgat tggttatttt
    20701 ttctggaatt atggtgtatt ttatgagcaa tgttaatgaa tataaaataa aaaaacaatt
    20761 gttttgtata tatgatgtgt ataaatatat ttatatattc atatttacaa aacaattgaa
    20821 atttatgtta ttttatgatt ttaaatttag atggaatttt aacttctgct ttatctttta
    20881 ttttagaagc ttgtttttta actttattta ataattcaga ttcatctaca actaatactt
    20941 ttctttcctt catcaaccat ttaccatcac aaatagtaga atctacattt tcactagtca
    21001 tagaataaac tatatttcca attggattat gcattggtaa acaatgaatt gtatctggat
    21061 ttagaataat catatcagct ttttttccta cttcaagact accaatttct ttttctagta
    21121 aagcacattt tgctccattt atagtagcca tttctaagac ttcttcagct ggtacgacag
    21181 ttgggtttaa agttctacct ttatgtatta gtgatgtaag atacatatcc ctcataaggt
    21241 ccattctatt atttgaagga gctccatcag taccaattga aacaggtatt cctttttcta
    21301 acatttcagg aattgaggca aatcctagaa ctactttcat agctgcacct ggattatgag
    21361 aaacttttac atcatgtaat ctaaataaat caatttcttt atgagtaagc caaactgtgt
    21421 gagcagctaa aagatttggt cctaatacac ctagtttatc aagatattca actgttccaa
    21481 ctccgttgtt ttgctttaca aatgaaattt catcagctat ttcagcaata tgcatatgta
    21541 tacctgtatt gtatttatca gctaactctt tagtcctaat aagcaattct tcagttgtat
    21601 taaaaatagt tcttaatgca aaccatattt taatcctctc attagatgtg ttattaaact
    21661 tatggaataa gtctaattga gtgttgattt cctcatcagt agttttttgc catgcttcag
    21721 gaagaccatc tcctgtatcc ataactgatt tagctaaaca ggctctaagt ccagttttat
    21781 caacagcttc aaccatagca tctacatatt gaccaccaga ttctaaaaat gtagttaccc
    21841 cagattttat caattcaaca caacatgcag tagatgaaat caatgaatct tcatagttga
    21901 agctactttc gtatggccag attctctctc taagccaagt taaaagtaca acatcatctg
    21961 caagaccacg tcctaattgt tgggataagt gaacgtgtgt attgactaac cctggcatta
    22021 gtatttttcc tttagcatca tatatctcag catctttatc tacaatatta atatcaaact
    22081 taccaacatt ttttataata ttattttcaa taagtatact tccagtttca tatacctctc
    22141 tatctgcatt catagtaatt agatatgcat tttttataag taattgtgac ataagtacaa
    22201 cctcttttct atatattttt atatctatgt attatgataa taaattttct atacaaagtt
    22261 aatagcaaaa tcaatttata cataaattga ttttgctatt tataaattta aaatattgac
    22321 ctagaactat ttaaaatatt aacttagaac taagtttaca actgcaagta aacctataat
    22381 ccaaagtgta atactgattt tatcagtttc tttagctacc acatgcatta ttatatatga
    22441 aataaatcca aagcataaac caatacttat actataagtt aaaggcatca ataaaactgt
    22501 aacaaaagca ggtacagcta ttttgctatc agcaaaatca atctgtttta tgctttcaaa
    22561 catgaataca ccaaccatta caagtgcagg agctgcagcg taagtaggaa ctataccaag
    22621 caatggtgta aatataagtg tagctaagaa taatgctgct gttactattg aagcaagtcc
    22681 tgttcttgca cctgctgcga taccagaagc agattctcca aatgttgtaa cagtactagt
    22741 tcctaagaat gagcctatta aagtagaaga aacatctgca tataacattc ttcctaaatc
    22801 ttttatttca ccattctcat cttcaagacc catttgttta caacaagtaa taagaaatgc
    22861 taatgaatca aacatgtcta taaacatgaa agagaatata ggtccaatta atgagaattt
    22921 caatgcacct acaatatcta atttaaaagc aactggtgct atactaggag gtgttgagat
    22981 tattgctgtt ggcaactcca caaatccaaa tataacagat attattgttg caactactat
    23041 acttatcaat attccacctt taactttttt atattctagt attgccatta agataagagc
    23101 aaaaagagct attaaaactg ttggtgtaaa atctgcaagt gaaactatag tatctggatt
    23161 agctattata acacccatat tttttaaacc aacaaaagca aggaaaagac ctatacctgc
    23221 tgaagatgct actgccaatt ctctaggaat tgcgtctgca attgtctttc gaagacctgt
    23281 tactgcgagt gtaaagaaga cacatccaga tagaaaaact accccaagac ctgtttgcca
    23341 tgggattcct gcacctataa ccaaagagta tgtgaaaaat gcatttaatc ccataccagg
    23401 agctagagca aatggtgcat ttcctaaaat cgcaaatata agtgtaccaa tggctgtagc
    23461 tagtatggta actgttataa gggcggcttt atccattcca gcttcagata atattgctgg
    23521 atttacgaaa actatgtatg ccattgttaa gaatgtagta actccaccta ttacttctgt
    23581 tttaaggcta gagccacgtt cgctaaattt aaacattttg tctaaaaagc ttaatgatga
    23641 attatttcca tctggttgta cattgttagt gtttggtacc atttttacct ccaaaaaact
    23701 ttaagatata aacaaaaaaa tatatattca tatagataga atagaacata tattcaaagt
    23761 tgatattcta ttcatagaaa acccatttaa ggtgagtttg tagaaactat tagaccgtat
    23821 tactaatatt atatgaacat tttctatttg tttttctgtt gtattatatc gtaatattgt
    23881 attatttaca ataaatataa taaaattatt cgtttttttg tcgattttat aaaaaattaa
    23941 ggttatttat tggcaagaat tactgttttc aataattgaa tatgtataag tataatgtca
    24001 attattctaa cttgttttat actattatat agaagtctat tataaatgag tttgtgatat
    24061 aattataaaa gtactgaata cacggatatt tcgtaaaaac tttttaatat atcaaatatg
    24121 tatattaagt taatatatta aaaaaaataa tatcaaaaat aatataattt atagtggagg
    24181 ggaaaatgac taaaattatt aaagtgcaaa aacctaaatt tacaggagaa ttagaaatta
    24241 ttgaaaatct tgaagatata cttgaagata tatttaatga tgaaaaaata tttaataaaa
    24301 ttatagaaaa tgaagttata agtgatttag attctgtaag agttagcttt gaatcttgta
    24361 tatttagaaa tgtatccttt gaaaattgca atttaaaaaa gattgattta cttgatgtgg
    24421 tatttgaaaa ctgcaattta tcaaattcat tttttgatgg aggaagtata tacagagttg
    24481 aatttaaaaa tagtaaattg ataggagtta gatttgatga ttgtatactt aaaaacgttt
    24541 tgttcaagga tgttttaggt aagtattcta acttttcatt ctctaaattt aagatagttt
    24601 ctatcttaga ttcaaatttt gaaaattctg tatttcaaga agtaaaaggt gacaatctag
    24661 tatttgagta tacaaactta aaaaaagcaa actttaatgg aactaaactt tctggcatag
    24721 attttaccac taataatatt gagggaattg agattggtat agatgagatt agaggagcaa
    24781 tttttgatgt gtcacaagca attgatttaa cgaaattgat gggaattatc ataaaatgaa
    24841 aaaaatattc ataaaataaa ttgggaaaac gttaacaatg tgtgaatttt taccagattg
    24901 acatttttct gaaaataaag taagattatc ttaatattca aaatattttc aaagggggta
    24961 atttagtgtg agtaagcaga tgagagatat ttttatagtt ggttttgctt tattttctat
    25021 gttctttggt gcaggaaatc ttatgtttcc tccattttta gggatggaat ccggcaaaga
    25081 ctggttaatt cctcttattg gatttgttgt tgcagatgct ggtatagcaa tgcttgttat
    25141 tatagcaaca gcaagatgca agggaagcat ggatgatgta cttaggagag ctggtaaagg
    25201 gttagcaaga gtaatgagtg tagctgctct agcatgttta gcacttcttg taataccaag
    25261 aacttgtgca acaacatatg aaatgggtat tatgcctata tttggagacc atggaccagt
    25321 agctaaagct atattttcaa taatcttctt tgggttaact ttagcattta ctattaggtc
    25381 ttctaaggtt atagacataa taggtaagta tttaactcca gcgttattat tagtattatt
    25441 tgttttaata gtaaagggta taatttctcc agcaggacct atgagtcctg agcatatgat
    25501 agataaaaat ctatttggtg aaggtatatc acaaggttat caaacaatgg acgctctagg
    25561 tgcagcatct atggcaacta taatgttgat gtctataata gctaaaggat atacatcaga
    25621 taaagaccaa ataggaatga ctattaaagc tggttttgta gcctgtgtat ttctagcagt
    25681 agtatatggt ggtcttactt atttaggtgc aacagtttca actttatatg atactagtat
    25741 acctcaagca tctttattag ttgaaataac tagtatattg ttatatggtc aagtaggaaa
    25801 ggtaatttta ggtgtaattg tggcacttgc ctgtctgact acttctacag gtttaacagc
    25861 atcaatatca acttattttg aaggaataag taaggcgagt tataaacaac tggttatagg
    25921 tatatgtgta gctagtatgc ttatatcaaa tttaggtgtt gattctataa tagctatatc
    25981 agttccaatc ctacaaacta tatatcctgt tttattagca atagttgtta tggagttggc
    26041 tggtaaacat ataaagaatg ataatgcttt taaaggtgca gcatatgtta cattagtgat
    26101 tagtctatta tcagctataa atggaatgac aggagctgtt ccatttatac aaagcttgcc
    26161 actcgcaggt ttgggcttta actgggtaat accagctata ttgggtggaa tagttggtaa
    26221 ctttataaaa agcaacaaac aagtagcata ataatttgta attaatttaa ttttataata
    26281 tattaatttt tagtactatg ggtaggttta atctaaacct aatctaccca tagtactttt
    26341 tagattggat tggaatagca tgtatataat tttttataat ataatttttc tttgaagtat
    26401 gataaaatta gtaatagtga taagaaagta caaatttagg aggttttaat taatgcttag
    26461 aaaaataaca gcatttatgc tatccatatg tttaattatt ggacttacag gttgtagttt
    26521 acttgtaggc aagaaagata aagagaaaat tatagatgat tttaaagttg cagtggtaac
    26581 tcaaccatta tctgaaaata aagtacaata caatatggtg gaagagatga caaaagaata
    26641 tgaggaagag aataaaattg ataaagacaa agatggtcaa actaaagtta aacaaactat
    26701 aaaacatgtt gtattgccag agaattttac ttctaatata gatagtgcta ttaataagat
    26761 agtaaagttg gctgacgata aagaagttca ggctattgta gtttcaactg accaagcagg
    26821 gcttttacct gctttacaaa aggtaaagga aaagcgtcca gaaataataa ctatttctgc
    26881 ccctatggga gatgataaaa accaattaag ccaatttgtt gatgtgaatc taggggttag
    26941 tgcagaggaa agaggaaaag tattagctga acgttcaaaa gaaatgggag caaaagcttt
    27001 tattcattat gcctctacag atgatttgaa agatgttaat atagccaaaa gattagaaat
    27061 gattaaagag acttgtaaaa atataggatt gccatttgta caagttaata ctccaaatat
    27121 aaatactgaa gaagacaaaa acaaagttaa gcagttttta aatgaagata ttgaaaaaca
    27181 agttaaaaaa tatggaaaag atataaatgt atttggtgta aatgagtata tggatgaagt
    27241 tatattgact aaggctttag aattaaagta tatagttgca gagcaaagca atccatcacc
    27301 aatacaaacg tatcctagtg ttatgggtct aaaaatatct gaaaaagatg ctcaaaatta
    27361 tgataaaata aacgacatga taagtgaaaa ggctaaggct tttggtatgt caaatagact
    27421 tggtggatat cctatgccaa tggatgcttt tctaccatca gtagcaattt atcttgctac
    27481 tgaaatggtg aaacaagatt taacacaaga agatgtatgt gacccagatt atttagaggc
    27541 gtttacagaa ttaagatttg gaatcggttc agaatttact cctttaacag aggtacttta
    27601 taattatcaa tcagtaattt taagccaatt aatttattaa tattaaggaa gtgtctcaaa
    27661 atgaactttt tagtttatga ggcactattt ttctgttaaa tcaaatatat ttttatcttt
    27721 ttaacaatta aaaagaagct tatccctatg ttgagata
//
LOCUS       DAMJWO010000056        27540 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.057, whole genome shotgun sequence.
ACCESSION   DAMJWO010000056 DAMJWO010000000
VERSION     DAMJWO010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27540
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.057"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            226..2319
                     /locus_tag="PC366_002430"
     CDS             226..2319
                     /locus_tag="PC366_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2577934.1"
                     /translation="MNKRNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPE
                     GKVCWQVLYPEQNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRVFENYDSLITWQD
                     GTVVHMHQSIDIANSTILNKPIKINEFNEISNTKEGKGVFNFSRDNFDYNSTLLYDAL
                     IRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVENPLIYWKKIVHPEDWNRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLNIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SIQSILPDNAELYKLDGDEMGILVDNVEENEILTLYNQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTQSHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMIN
                     IVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDENFPYQNL
                     VLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
     repeat_region   2980..3273
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=2980..3008
                     /rpt_unit_seq="gttttatattaactatatggaatgtaaat"
     gene            complement(3441..3725)
                     /locus_tag="PC366_002431"
     CDS             complement(3441..3725)
                     /locus_tag="PC366_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577935.1"
                     /translation="MLVRVKIVIGATIRYLIKHKVNYCNKKSLDKLELKYGNIDREKA
                     VKLEIFYQYLIELEYIEMSLLIRRLDTAITSLALVSIITIASYYLIRKNV"
     gene            3932..4750
                     /locus_tag="PC366_002432"
     CDS             3932..4750
                     /locus_tag="PC366_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2577936.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCK
                     SKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIG
                     KYEDSYKSYEKLKKYIYENEYKIIGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            complement(4883..7003)
                     /gene="feoB"
                     /locus_tag="PC366_002433"
     CDS             complement(4883..7003)
                     /gene="feoB"
                     /locus_tag="PC366_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF2577937.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLG
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKDSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(7029..7256)
                     /locus_tag="PC366_002434"
     CDS             complement(7029..7256)
                     /locus_tag="PC366_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2577938.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            complement(7583..8023)
                     /locus_tag="PC366_002435"
     CDS             complement(7583..8023)
                     /locus_tag="PC366_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2577939.1"
                     /translation="MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKS
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIK
                     INLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
     gene            8175..9164
                     /locus_tag="PC366_002436"
     CDS             8175..9164
                     /locus_tag="PC366_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HDF2577940.1"
                     /translation="MIYGGSVLNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDF
                     IVPVFFCIICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINK
                     PTMVMDDLVYGSVFGVIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLM
                     IALFPFGMVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRSLNQFLCCSKKAFYICV
                     SYLAIFEVLKLLNVKVDSVYLKTIFISITYISVYFIIRDSCMSLQNFIIAKFRKLLYA
                     RILFLIIILLLFFIFDVTVISLIIINAFLNKKINIRLSQSNIVNKQINLLIEK"
     misc_binding    9316..9568
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            9640..10848
                     /locus_tag="PC366_002437"
     CDS             9640..10848
                     /locus_tag="PC366_002437"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HDF2577941.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKEGSVNPRDIKMNLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     gene            complement(10909..11790)
                     /locus_tag="PC366_002438"
     CDS             complement(10909..11790)
                     /locus_tag="PC366_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HDF2577942.1"
                     /translation="MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPGRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            12176..13120
                     /locus_tag="PC366_002439"
     CDS             12176..13120
                     /locus_tag="PC366_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDF2577943.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLI
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
     gene            13343..13888
                     /locus_tag="PC366_002440"
     CDS             13343..13888
                     /locus_tag="PC366_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HDF2577944.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRHFGK"
     gene            13979..15127
                     /locus_tag="PC366_002441"
     CDS             13979..15127
                     /locus_tag="PC366_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HDF2577945.1"
                     /translation="MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQNSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKIHSKKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVLLASQNPYAIDVVACKIISLLPNRVATIRGAIKRGYIQEDFSDIEILG
                     EDIKDLIIKNYKIPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            15180..16445
                     /locus_tag="PC366_002442"
     CDS             15180..16445
                     /locus_tag="PC366_002442"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HDF2577946.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASELGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKVNYTICNGEIVYNA"
     gene            complement(16731..17963)
                     /locus_tag="PC366_002443"
     CDS             complement(16731..17963)
                     /locus_tag="PC366_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577947.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLVPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVIAKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFAATNYVSKYIGFEAIPSLNSLFYAIVATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(17966..18640)
                     /locus_tag="PC366_002444"
     CDS             complement(17966..18640)
                     /locus_tag="PC366_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577948.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKALKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLVN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            complement(18648..19877)
                     /locus_tag="PC366_002445"
     CDS             complement(18648..19877)
                     /locus_tag="PC366_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HDF2577949.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRNSSFGSSGFKSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTELQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKI
                     SLSDIAENKDAIASINAQITALNSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVANSSFKIPASCVLKDNKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     GDTTPNKKVEEVTMDVN"
     gene            complement(19989..20993)
                     /locus_tag="PC366_002446"
     CDS             complement(19989..20993)
                     /locus_tag="PC366_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2577950.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTVSVIIFSPVDVFLTDTILYI
                     LVVNVVFLFLYLFISYIKKNKFLDKIKNDTFKINMNDIELARCKNEEKIYLNIIKNHQ
                     YQCNNIINNNIEKFEENKEILNMWVHDVKIPIAIIKLILEQNENLINEKISDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILDLNNLN
                     FKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRTKNYLQLRVEDTGCGIKKEDL
                     NRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIDVDSEYNQYTKFTITFKCDL
                     "
     gene            complement(21017..21691)
                     /locus_tag="PC366_002447"
     CDS             complement(21017..21691)
                     /locus_tag="PC366_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2577951.1"
                     /translation="MFKIMVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNY
                     NPELVLLDINLPFYDGFHWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSVDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIS"
     gene            21979..22746
                     /locus_tag="PC366_002448"
     CDS             21979..22746
                     /locus_tag="PC366_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003722224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2577952.1"
                     /translation="MEEILSVENIKKEYGRKGSKHEALKGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTMDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRIKEISKELNIESILDKYPGEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
     gene            22733..24670
                     /locus_tag="PC366_002449"
     CDS             22733..24670
                     /locus_tag="PC366_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2577953.1"
                     /translation="MTLFRIAMQNVKNSFFNYLMYFISIVFSVFVFFSFKSIEYNEAL
                     SSLGEKTRMSINTSSIVIVVFVFLFIYYSNSFFFNRRRREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVKTLAVFLI
                     IFIVIGIRNTIVIRNKRIIELFNKYPEKYKFKKFIKLKCVLGVLLIAISYLMSISYFI
                     AENIMLSVFILVTIIPGTFLFFSSTMYMIIDAVKKRKSFYYKGQNLIAFSELGFKLKS
                     NSSVLAVIAILIATSVTMLGFTISLYYDIDRNISENYKYSYTINLGNSYVNNEIDKLL
                     YKYKKDNKIIFDKTIELIDKDINIEMYYKNGNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELTSKESVYYVSDSYKKMFFKDFEIEKINLYIKDTNEYDINLFKVQKSILEPEIN
                     SQATFDLIVVKDDVFNQLKLHGNSRLIRLIDIKNEKKELDLTLKFKNIVSENMKFTYP
                     FNFTSSIESYNNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDKERYIMLI
                     KLGANNKDIEKIISKQLKIIFLMPLVVGTVHNLFAMSIAQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMIKE"
     gene            24895..26508
                     /gene="ggt"
                     /locus_tag="PC366_002450"
     CDS             24895..26508
                     /gene="ggt"
                     /locus_tag="PC366_002450"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HDF2577954.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLMECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYR
                     GRLADKIDEYSKKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELELEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPKHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVEPEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(26641..27492)
                     /locus_tag="PC366_002451"
     CDS             complement(26641..27492)
                     /locus_tag="PC366_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HDF2577955.1"
                     /translation="MKNIISAKELISKLEKNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNDTTIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEEKVNIPSCTGKEIRPNINNDLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
BASE COUNT        10292 a         3387 c         4170 g         9691 t
ORIGIN      
        1 taatataaga gagagatgta ttatgtaata ttaatttttt ttaaattggt aatactatat
       61 tgctgtattt ttttttatca attataattt aaaatatgaa ataataaact ttctaattaa
      121 attaaggtat ttagtgtgta tgtataagtt ataagtaaat cttctaaaaa gaataatttt
      181 aacagtgttg ttataaagag cagtaactat ggaggagata agtatatgaa caaacgtaat
      241 tttgaagtta tattaaatca actacagatt aatatatatg ttacaaatat tcatactaat
      301 gaaattattt ttatgaacaa gaaaatgaaa gaagaatata atattttaga tccagaagga
      361 aaagtttgct ggcaagtatt atatcctgag caaaattcta cttgtagttt ttgtaaagtt
      421 ttagaactat taaagaatga taaaaaagga gtattaataa agtggtatga aaaatgtaat
      481 aagttaaatc gtgtttttga aaattatgat agtttaatta catggcaaga tggcacagtt
      541 gttcatatgc atcaatcaat agatattgca aactcaacaa tcttaaataa accaattaag
      601 attaatgaat ttaatgaaat atcaaatact aaagaaggaa aaggagtttt taatttttca
      661 agagacaatt ttgattataa ttctacattg ctttatgatg ctttgattag aggtacagat
      721 gaatatatat acatttgtaa tatgaaaaca ggcgtatttc gatattcacc atcacaagtt
      781 gaattatttg acttaccagg agaaattgtt gaaaatccgc ttatttactg gaaaaaaatt
      841 gtacatccag aagactggaa tcgtttttat aagtcaaaca ctgaaatagg taaaaaccag
      901 atggattatc atacagtgga atttagggct aaaaatcgta gtggagaata tatatggtta
      961 agatgtagag gacaactaat gcgtgatgaa tttggagaac caagtatttt tgcaggaata
     1021 atgacgcaat taggtaaaca aaataagatt gattcattga cacagttact gaattatcat
     1081 gaatttatga gtgtatttga agataaaatt tcaaatccta tgattgaaaa attatgcata
     1141 gtattattaa atattgacga ttttaaaaat gttaatgaga tgtatgatag ggattttgga
     1201 gataatataa taaaaacact agcacagtct atacaatcta ttttaccaga taatgctgaa
     1261 ctttataaac ttgatgggga cgaaatgggt attcttgttg ataatgttga agaaaatgaa
     1321 attctaactc tatataatca aatacagaat atgattatac accttcaact atggagaaaa
     1381 tatggattaa atataacaat ttctgctggt tgtgtaatat atccaaaaca tggagataca
     1441 gtaaaagaac tttataaatg cgctagttac tctttacaat atgcgaaaga gcatggtaaa
     1501 aacaggcttg tttttttctc ccaagaaata ttaaaaaata aaatgtattc attagaaatg
     1561 atgcgggatt taaaggcatc aattaatgat gattttaggg gatttagtct tcgattccag
     1621 ccacaagtag atacacaaag tcataaaata ataggtgtag aagttctttt aaggtggact
     1681 aatgacaaat gcaaagcaat ttctcctttg gaatttattc caatattaga agaaaatgat
     1741 atgataaata ttgtaggggc ttgggtgctt cgaatggcat tacgtacttt taggaaatgg
     1801 attgattact atcctttttt taaagtgagt gtaaacgttt cagctgttca aatattagaa
     1861 gacacattta ttgaagatat agtaaaaatt atagatgatg aaaattttcc ttatcaaaat
     1921 cttgttttag aattgacaga aagtcataca gtacaaaata tgagtatttt acagtttaaa
     1981 tttaaggctt tacaagattt aggaatttat attgctatgg atgattttgg tactggatac
     2041 tcgtctctag aagttttaaa attttctcca atagatatag tgaaaattga tagagtattt
     2101 gttaaagata tattaaagag taagtttgat gctacattta tacattttat tgttgcaatt
     2161 tgtcatgatg taggaataaa agtatgttta gaaggtgtag aaacacaaga agagtatgat
     2221 ttagttaaac aaataaagcc agattacata caaggatatt tatttggaaa accgcagaca
     2281 gcaacagaaa tctttgacct tttaaagcta gataattaat tctaatttat caataatatc
     2341 actgaaaagc tttaaaatca aaaatacatt aaattattat attgaagata tatcaattat
     2401 aaattgcaat ataagaaaat agcatttcaa gggatgttaa attaggagta gtatatgatt
     2461 aaagtatttt aaaaagggat aactataata aaaatagata tctattttta gattaaaaat
     2521 aatatatcat aaataaaata ataagaggta gatacagttt taagggaata caaaagtttt
     2581 taattaaact atgcttgttc agatagatat ttatttaaga aaaaagacta ttaaaagcaa
     2641 tatacaagaa tgatatatta gattgattaa acaagcataa atattatgta aaaaacttta
     2701 agttatagaa tttaaatcca atgtagatag attacgtttt ttcttgcttt tattatggta
     2761 taaattggta tcaatattca aaagtaatat atttatgata taataaaatt atagaaattt
     2821 tgcagtgagc tatatttgtg ataaaatttg gcgtaacagt tgaaatataa ggtgttgaga
     2881 gtgcatgata agcgttatca attgcactat tgctcgttca ctgcaaattt aggagagttg
     2941 tatacgtgta agtgttgaaa atactaagtt tattttgggg ttttatatta actatatgga
     3001 atgtaaatct cggagaattt cctaatgtgg atttaatagg aagtgtttta tattaactat
     3061 atggaatgta aattttagca aatttttcgt aaaagtcact attttcaatg gttttatatt
     3121 aactatatgg aatgtaaata catataaaac tttcatcttc tgttaattca ttaaaacgtt
     3181 ttatattaac tatatggaat gtaaatccat cttttgttgt tttacataaa tttatattac
     3241 ttacgtttta tactaactat acggaatata aatttttata attttctttt aatgtgttat
     3301 cttatgatta tctagttata ttagcataca aaaatataat aaaattacac tatattataa
     3361 aaaccaaaag gtagtataga aatcctatta cctttttatt attaatttta tcagtgtttt
     3421 attataaata gcttacataa ttacacattt tttctgatta aataatatga tgctattgtt
     3481 ataatagata ctaatgctaa tgatgttatt gcagtatcta atcttcttat taataaactc
     3541 atttctatat attcaagttc tattaaatat tgataaaata tttctagttt aacagctttt
     3601 tctctatcta tatttccata ctttaactct aatttatcta aagatttttt attacaataa
     3661 ttaactttat gtttaattaa atatcttatt gtagcaccta ttacaatttt cactctaaca
     3721 agcataaata taatattcca tccaaaagtt aagaggggat atctttttta tgagaggaat
     3781 ggataaaata tttataactg acatctaact gatatttaag ctttaaaatc aaaaccatat
     3841 tgattttcta aaataataac tacttgattt agtaaataat aaagaatata gtaactatat
     3901 agacaacaaa aagaaaagga gtgtataacc cttggaaaaa cagtatttta caacaggtga
     3961 atttgctaaa ttgtgtggta tatctaagca gacattaatt ttctatgaca aaataggtat
     4021 tttttctcct gaatataaag ataaaaataa ttatagatat tactcagttt atcaatatga
     4081 tacacttgat atattacaat cattaagaga aataggaatg agtttagagg aaataaaaga
     4141 gtatatacaa aatagaactc cccagctttg tgtgaaaatg cttaaagaag aagaaaaaaa
     4201 gataagagaa aaaataaaaa aactaagaaa gataagctct aagatgcaaa atagaataaa
     4261 tataacagtt gaaggaattt ctaaaatgaa tagtgaagaa atttatatat ccaaaaagtt
     4321 tgaagaatat ttagttctat caagcgattt gagtaatatg agtaatagtg attttatgat
     4381 ggaattaata gatttcacca attattgtaa atcgaaaaat ttgtatcaag gatatgagtt
     4441 gggagtaata gtaagtaatg aaaatataaa aaatggggac tatttaagta tatcaagttt
     4501 ttatttgaag atagataaaa aaataaagga taaaaagcta tatgtaaagc cagaaggaat
     4561 gtatgcttgc ataaaacata ttggaaaata tgaggattca tataaatctt acgaaaaatt
     4621 gaaaaaatat atatatgaaa atgaatataa aattattgga aattcgtatg aggagagtat
     4681 acttgacttt ttttgtgaaa gtaatgaaga taattatatg actgaaattt caattcaagt
     4741 atccagataa gaattaaaat agagatatat tcaaatgtta agtaatttta cttatcattg
     4801 aatatatctc tatgctttat aataaagtat ataaattttt aaatagtttc tctaatatat
     4861 gtctaatgtc agttaatact aattatataa ataaattgta aactgtagtt gttaaaaaac
     4921 aaacaacaaa agcaagtata gtaggcatta agaatcctaa ggcagtccat tttaaactac
     4981 cagtttcttt ttttattgtt aaaagtgttg ttgcacaagg ccaatgcagt aaactgaaca
     5041 gcataacatt taaagctgtc aaataagtcc atccatgttc tctaagaact tgacctaaag
     5101 cactaaagct atctaattct atcatagaac cagttgctag gtaagccatt aaaagtatag
     5161 gtacaactat ctcatttgct gggaatccaa gaataaaagc aagtaatata aaaccatcaa
     5221 gaccaattaa tttagctaaa gggtctaaaa agtttgcaac atgtgataat atgcttaaat
     5281 ctcctatata tatatttgca aatatccaag ttatgacacc agcaggtatg gctaccatta
     5341 cagcccttcc taaaacaaat attgttctat ctattataga ggtatataaa gttcttccta
     5401 tttgaggaac tctataagga ggaagttcta atgtaaatgt agacggaact ccttttaata
     5461 gcgtcttaga aagagtataa gaaaccaaca atgttattat aacacctaga attatcagta
     5521 aagttatgca aagtgcagtt gctacgcttg atacgaaaga gttggttata actgagctaa
     5581 aaaatattgt agatatagct atcaaagtag gaaaacgacc attacaagga acaaagttgt
     5641 ttgtaagtat agctataagt ctttcccttg gagagtcaat tatcctacaa ccaataactc
     5701 cagctgcatt acatccaaat cccatacaca tagtcaaaca ctgttttcca tgtgcacaag
     5761 cttttttaaa taggtggtct aagttaaatg caactcttgg caaatatcca aaatcctcaa
     5821 gtagggtaaa taatggaaaa aatattgcca taggaggtag cattacagag attacccatg
     5881 ctaatgttct gtataatcct aaaaccaaca tatcatttaa ccatgatgga caattaatac
     5941 tatttaatat acccgaaata cttggctcaa atccgagtaa taaattagat aataaagtgg
     6001 atggatagtt agccccttct atagtaatcc acaatatagt acctaataat aagagcatta
     6061 ttggaagccc aaatatttta gatgttaata ttttatctac tttttcttct ctatcagttg
     6121 attttttagc aacattagaa caacactcat cactcagttt tttagcataa tcatagttga
     6181 ttttagtaaa ctcatctctt attttctgtt tatttatatt gtctggaatc tttttcttta
     6241 cttcattaat agcatctata gaatctttgt ctatataatt actcatagat tcaaatatac
     6301 tttcatcgcc atcaataagt ctaagtccca accatctaga atttatacct ggtataatat
     6361 tatccaattc tggttgaatt gattttacca cattctctat attttcattg tatctaacag
     6421 gtttattatt taatttgtat ttgtcaaaag atacatcatt taaagtatcc aatagttcat
     6481 ccataccaga gccatttctt gcagcagtta aaataactgg aataccaaga gaatcctcta
     6541 aaagtttttt atcaatagta atgccttttt ttctagcttc atctattaaa ttaatacaca
     6601 aaataacttt atctgtaagt tccatcactt gaaatactaa atttaaattt ctttcaagac
     6661 atgtagcatc acatactact attactgcat ctggattacc aaaacatata aaatcacgag
     6721 ctacaatttc ttcttgtgat aaggcaaata aagaatatgt tcctggtaaa tctattaatg
     6781 catattcggt atttttatat ttaaaattac cacgagctgt agctacagtt tttcctggcc
     6841 agtttccagt atgctgtcta agccctgtaa gatgattaaa tacagtactt ttacctgtat
     6901 ttggattgcc agccaatgca attacaaact ggtcttcctt attgtctata tcaaacatat
     6961 cttttaaaga actcatttta gttgagttat gtgtcaaccc catattaata tcctcctgct
     7021 agaaattttt aaatgtcaga aactaatatt aagctacttt cttcttgtcg tagagctatc
     7081 ttactacctc tgattttata gacagttaaa ttattttttg gaccttttct aactacatct
     7141 ataacagctc ctctagtaag accaagcgct aacattcttt ctcttaaatt accactagat
     7201 aatatatctt caactttgac agtttttttc acttgaatat cgttaaggtt tttcatagta
     7261 gcacctccat gcttgaaatt tagcctgggc taatcttctt attctaaact atgcattata
     7321 ttattacctt gttactttta caaaaaaaag ataggcaaga tgcctatcat acaaagttgg
     7381 gtataattct tacttttggg gaaagtagaa tatagaataa aaattaacac tttgaatcca
     7441 tataattatt gaattttgat aataaaaaag tcagaaagca aaagcctcct gactctatgt
     7501 aaggtatttt caaataccta aatatcaatt caatatttaa tttatactta aattatatat
     7561 taacaatatt agcttgtcaa cactataatc tcattttaat atgttcaata cctgcttcgt
     7621 cgtatacttc tgagatttct ttaaaaccac aagataagta aaggttcttt atataagttt
     7681 gtgctgataa ggttatatta ttttcgtgta agttaatttt tataaaatct atagcacaat
     7741 ccatcatttg ttttgctaat ccttttcttc tatgactaga aagaactaaa actctaccaa
     7801 tggaaacatc attataagag ctgtattctt taggaattat tctagcataa gcacaaatca
     7861 atccattttc ttttaaaaat atgtgataag agcttttatc tatatcatca taatcgttta
     7921 atgaaaatat cttctgttca caagcaaata cctcatatct tgattttgct atttcataaa
     7981 attcatctaa actcaaatca ttaaagtgtt taattttaaa catagtaatt acctcctagc
     8041 atcttaaaaa actgaatatt aagatacatt ataccatttt taacataaat acctttatta
     8101 aaatttatat ttattaaaaa tatttttaaa aagtgatata ctatattaaa aacaaaactt
     8161 tagttagaaa atttatgatt tatggaggca gtgttttgaa tactactaaa aaattaactg
     8221 aagcagcttt attgtcatct ttattcatag tagtaacaat tatagctgtg agtactggat
     8281 ttggatatgc tatttactta gattttatag tgccagtatt tttttgtata atctgcttga
     8341 aatgtgattt aaagtatacc attttatctg gaattacttc acttttaata atttctctgg
     8401 tacttggaaa tctaggaact gctatttggg caagtcagag tgtattactt ggtataatgt
     8461 gtggctatct aataaataag cctacaatgg ttatggatga tttagtatat ggttcagtat
     8521 ttggggttat tgtaatggtt ttcattgata tatatgcttc aacattaata ggttatagtt
     8581 ttatgaaaga atttcaagga tatagcaaat ggatttattt taatgggtat acaaatttta
     8641 tttattattt aatgatagca ttgtttcctt ttggtatggt gttttgcata tatttattaa
     8701 gtttaatttt agggaataaa ttgcatattt tagattctaa ttctttaaaa aaatttttaa
     8761 tatttaagaa ttttagaagt ttaaaccaat ttttatgttg ctcaaaaaaa gctttttaca
     8821 tatgtgtttc ttatctagcc atttttgaag ttctaaaact gttgaatgtt aaagttgatt
     8881 ctgtttattt aaaaacaatc tttatatcaa taacctatat aagtgtctat tttatcatta
     8941 gagactcatg tatgtcacta caaaacttta taatagctaa gtttagaaaa ttattatatg
     9001 ctagaatttt atttttgata ataattttat tgctgttttt tatatttgat gtaacagtta
     9061 ttagtttaat aattataaac gcatttttaa ataagaaaat aaatataaga ttgagtcaga
     9121 gtaatatagt caataaacaa ataaatcttt tgattgaaaa ataaactttg ggtattggta
     9181 aaaaatataa aaaagtagta taatgtaaaa aaacatgtat ataataataa aaaaggttga
     9241 caaaatataa aaataataat atattatgag taagttaaga aaaatttctt gtaattgatg
     9301 aaataatctg aatatataaa tgctatgaag agaagaagta gggctagatt ttatttaaca
     9361 gagagttcca gtttggtgaa atggaataaa ttgatttagt ttgaatacat ctcagagcac
     9421 tatctctgaa agataacaac cattaagaga tatcggatta gtacacgtta tagtacacga
     9481 gtatatgtaa ttgtactcta agagattaat atcgtgagat attgatgaac taaggtggta
     9541 acacgtaagc aatgctttcg tccttttaag aggatgaaag ctttttttat tataaaaaaa
     9601 aaattataga ttatataaat attttaggag gaatgaaaaa tgaaatcgat agacgagcaa
     9661 atgcgaataa ttatgaaagg tgtagatgat ttaatagatg agaaagagtt aagggaaaag
     9721 cttattaaat cagaaaaaga aggaaagcct atgatagtaa aattgggtct agacccaagt
     9781 gctccagata tacatttagg gcatacagta gttcttagaa agatgaaaca attacaagat
     9841 ttaggtcatc aaatagtaat aataattgga gattttacag gaaaaattgg agacccaact
     9901 ggaaaatcta aagctagaaa agctttaaca acagagcaag ttcttgcaaa tgcaaaaact
     9961 tatgaagaac aaattttcaa agttttagat aaagaaaaaa ctattgtaag atttaatagc
    10021 gagtggttag ccaagttaaa ttttgaagat gtaataaaat tagcagcaac tattactgtt
    10081 gcgagaatgt tagaaagaga agattttaaa aagagatatg aaggacaaat gccaatatca
    10141 gtacatgagt tcttctaccc attaatgcaa gcatatgact ctatagcatt agaagctgat
    10201 atagaacttg gtggaactga ccaaagattc aatttactaa tgggaagatc attacaaaga
    10261 gaatttggta tggagtctca aatagtaata atgatgcctt taatagaagg attagatggt
    10321 aaagaaaaaa tgagtaagag tttaggtaac tatattggaa tagatgaaga agcgggaata
    10381 atgtaccaaa aatctatgga aattcctgat gaacttataa ttaaatacta caatttagtg
    10441 acagatgttc atcctgatga agttaataaa atagaatctc agttgaaaga gggttcagta
    10501 aatccaagag atataaagat gaacttagca agagaaatag taacattata ccatggagaa
    10561 gaatctgcta aagaagctga agaaagattt aaatctgtat tccaaaaagg tcaaatacct
    10621 gaagatatac aaacaattca agttaaggaa gatggatttg acttaatcga agtactagtt
    10681 tctaatgaga ttgttaagag taagagtgaa gttagaagat tagcttctca aggtggagta
    10741 aaggtaaatg gtgaaaaagt agaggattta agcactattg taaaagagag tgaattagtt
    10801 gttcaaatag gaaagaaaaa atttgtaaaa atcgagctag taaaatagag taaagtaaaa
    10861 gcaagtctat tgagtataaa atgtacattc aataaacttg cttttttatt atattaaaat
    10921 tttaaattga taaccattgt ctttaaaata tgttataatt tggtccaatg catttactgt
    10981 ttcttgtttt ccataagtat catgcattaa aagaacaacc atttctttgc cttcagaaga
    11041 tttctttgca tgttcaaata attcttgtgc atttttcttt ttaccttctg catcagcatt
    11101 taaagcgttc caatcaattg atgccatgtt tttctctttt aagtagtttc ctagaggttc
    11161 catatttttc catgacatat acccgcctgg gcatctaact acatttgagg aaaaattctt
    11221 tcctaagact tttttcatag cttcatcagt tttgttaagt tcatttacga atgtatcgag
    11281 atttaggctt ctgccaggat atagtttttt atagtcatgg gtataagagt gatgggctat
    11341 tgcatttcct tcgtcaaatg ttctttttaa aatttcatta gctccttttc tttcaagaga
    11401 atcaccctta ataaagaaag ttcctctaac accatgtctt ttcaagatat ctagaacttg
    11461 tggagtatta gtagtagatg gtccatcatc aaatgtaaga aagactatct tttctccatt
    11521 gtttgaatag tcgtatttgt taagtttgtc ccaaactatt tttgcgtcat atccatattc
    11581 ttttacagct tctttttttg caccaataat aggttcattt ttttcttttt caattctttc
    11641 tttttctaat ctttcagctt taagtctttc ttgagtttct ttcatttctt tttttctaga
    11701 catgtccgcc catgccatag aaaaaatacc aataactatt acaacaagta tagtaagtgt
    11761 aacagttttc ttttttcttt tttttaccat aattacagca ttcccccttt tgtcgaattg
    11821 tatcaaaaat atattataat tatatcgaag aaagtagaaa aagtaaaccg acaaagttgt
    11881 aactaagata actaaagtgt aacttatatg acattatttg cataatatta aagtatcata
    11941 tatattaaaa atatctataa aaaaatttag tataggtaaa aaaatataaa aaatataaaa
    12001 atttattaaa aaggtgttta caaaaaatga ttaatatatt actgttaaat agtggatata
    12061 aatttgagct caaaatgtat gtaaatttag atttaaaata ctgaaaaaat ttactatatt
    12121 aatttatagt aatgcttata gaaaaactct cttgctgttt agggggttta taattttgca
    12181 aaaaaataaa aaggaggggg ctttattgaa aaaatacttt ggagaaatag gactaatatt
    12241 tatagcaatt atatggggaa gtggctttgt agcaacccaa tttgcattag acggtgggct
    12301 tacacctcta caaatcataa ctttaagatt tttcttggca gctataatta tgaatttact
    12361 gttttttaaa cagattcgtg ccaatatggg taaaaaatta ttaaaagcag gagggatttt
    12421 aggaatattt ttatttctag cattcacagt acaaactatt ggacttatgt acactacacc
    12481 atctaaaaat gcatttataa cagcagctaa tgttgtaata gttccgttca taggatttat
    12541 actttataga agaaaacttg ataaaatagg aataataagt agtttggtag ctcttatagg
    12601 aattgggata ctttctttag aagctgattt ctctattaat tttggagatt ttctaacact
    12661 tatatgttca ttcggatttg catttcatat attctttaca agtgagtttg caaaagataa
    12721 caacccaatg gcattgacag ctattcaatt tacagtagcg tttttaatgt ctgttgtagt
    12781 tcaaacattt gcaggtcaat taaagatgga agctgaatta tctggttata tgggaactat
    12841 gtatctagct gtatttagta ctacaattgg atttttattt cagactatat gtcaaaaaag
    12901 agttgatgga actagaacag ctataatatt atccacagag gctgtatttg gtacaatatt
    12961 ttctataata attctaaagg aacttattac agcaaaattg attattggta gtatcttgat
    13021 atttgttgca atcataactg cagaaactaa attatctttt ttaaagagca aaaaagtgaa
    13081 acttaaagat tcagaggagt cttcattaga aagtatttaa tatgacaact atttcctaat
    13141 taatcaaata agttatgtat tatgtagaaa tttgacatca aaacttggtt gatactggtg
    13201 tttcaaagtg ataaaattaa ttaggaaata aattttattt ttagtgttta agctataaag
    13261 tctggggtat atatattctt gtagcaagtt attaaactta aaaataaaaa tttaattata
    13321 taaaattggg aggaaattaa ttatgaaaaa atttgtttgt acagtatgtg gatatataca
    13381 tgaaggagat gctgcaccag cacaatgtcc agtatgtaaa gttggagctg ataaatttga
    13441 agaaatgaaa ggcgaaatgg tttgggctga tgaacataga ataggagtag ctcaaggtgt
    13501 agatgcagaa ataatcgaag gattaagagc taactttact ggtgagtgta cagaagtagg
    13561 aatgtattta gcaatgagta gacaagctga tagagaaggt tatccagaag tagctgaagc
    13621 atataagaga atagcttttg aagaggctga acatgctgct aaatttgcag aacttcttgg
    13681 agaagttgta gttgcagata caaaagaaaa cttaagagtt agagttgatg ctgagtatgg
    13741 tgcaactgat ggaaaattaa aattagctaa gagagctaaa gaattaggat tagatgctat
    13801 acatgataca gtacatgaaa tgtgtaaaga cgaagctaga catggtaaag cattcttagg
    13861 attattaaac agacattttg gaaaataata attaaaacat agattaaaag gagaaacttt
    13921 ggtttctcct tttttaaatt atacaaataa actgttgtga tagaaggatg gagataatat
    13981 gaagtcggta tctgttagga gttgtaaaac ttacaattat gaagaagtaa agttatctat
    14041 tgaaaaaaat ttagaggata ttggtggtat agataagttt gttaaaaaag gaagcaaagt
    14101 acttataaaa ccaaatttat taatgaaaaa aaagcctgaa gaagctacaa ctacacatcc
    14161 tatggttgta aaagttgtat gtgaaaaact tttagagtta aattgtgata ttacaatagc
    14221 agatagccct ggtggtccat ataatcaaaa ttctcttaag agcatttata aggcatctgg
    14281 aattgaagaa gtagcaaatg aactgggcat taagttaaat tatgatgttt cagatgttaa
    14341 gatacatagt aaaaaagcac atgttctaaa atatatggat attattaaac caatagtaga
    14401 ttcagattat ataataaatc tttgtaaatt aaagactcat ataatggcaa cctttactgg
    14461 tggtacaaaa aacttatatg gatgcatagc aggattgaaa aaagcagaga tacattatag
    14521 atttcctaca gaagagttgt tttgcgaaaa tgtactttta gatatttgtg attatataaa
    14581 accaacattg acaattatgg atggtatagt aggtatggaa ggtgatggac cttcagctgg
    14641 tactactcga gaaataggag ttttattagc atcacaaaat ccatatgcta tagatgttgt
    14701 tgcatgtaag attataagtt tacttccaaa tagagttgct acaattagag gtgctattaa
    14761 gagaggctat atacaagaag atttttcaga tattgaaatt ttaggtgaag atataaaaga
    14821 tttaattata aaaaattaca agattccaaa tgtaagtaag gatttaagat tgttttccgt
    14881 aaagctacca aaatttttaa atgaacctat ttcaaagctt ataacaccaa agcctgtggt
    14941 aagatttcaa gattgcataa aatgtggaaa atgcaaggaa gcttgtcctg catccactat
    15001 agagataggg actaaaggtg ctattataga cttaagtaaa tgtataagat gttactgttg
    15061 ccatgaactt tgtcctaaaa aggctattga tgtcaaacgt aattttgtat ttaagtatgt
    15121 aaaataatgt ataatattat atgagtctat ataaattaaa aatataaagg agaaataata
    15181 tgattttaat taaaaatggt agagtaatag accctaaaag tcaaagagat gagaatattg
    15241 acttaattat aaaagaaaat aaaatttata aaataggcaa gtttgatgaa agtgatgaat
    15301 atgaaaaaat aatagatgct agtggtaatg tagttgctcc aggtttagtg gatgtacatg
    15361 tacactttag agaccctggg tttacatata aagaagatat agaaagtgga gctaaatctg
    15421 ctgctagagg tggatttaca actgttatat gtatggcaaa tactaatcct attgtagata
    15481 atgaagatac ttttaattat gttaaagaaa agtcaaaaaa tgcatgtata aatgttttac
    15541 aagcagcagc tataactaaa ggttttgaag gtaaagagtt agttgatatg gaagctctta
    15601 aaaaagctgg tgtaccaggg tttactgatg atggattacc tttaatggat agcaatctaa
    15661 ttatggaggc aatgattaag gcaaaagagt tggatgtacc acttagtttt catgaagaag
    15721 acccttcttt agttggaaat ccaggtgtaa atgcaggaaa ggtagcttca gaactaggat
    15781 taaaaggtgc atcaagtgta gcagaagatg ttatggtagc cagagattgt atgttggcac
    15841 taaagactgg tgctaaagtt gatatacaac atataagttc aggtgtatct gttgatatgg
    15901 ttaggtttgc aaaatactta ggtgcaaatg tagttgcaga agcttcacca catcacttta
    15961 cattgactga ggaagatgta ttggagtttg gaacaaatgc aaaaatgaat ccacctctaa
    16021 gaagtaaatg ggacagagat aagattatag agggattaaa tgatggtact attgaaataa
    16081 tagcaacgga ccatgcacct catagtaaag aagaaaaaga tagagagttt ataaaagctc
    16141 caagtggaat tattgggctt gaaacttctt tagctcttgg aataacaaat ttggtgcata
    16201 aaaatcatct tagtatgatg cagttaatag aaaaaatgtc tataaatcct gcaaagttgt
    16261 acaatttaaa tattggattt atagaagaag gggctgtagc agacattgtt atattcaatc
    16321 cagaagaaga atggacagtt gaaagctttg tttctaaagc tgataattca ccgtttaaag
    16381 gtaaatcttt atatggaaag gttaattata caatatgtaa tggggagatt gtatataacg
    16441 cctaatttaa gattattttt ttaaggcgga gtgtacaatg attgaaagta aaagattgta
    16501 tatcagcaga atgagattga ttaatcaaaa ttggaagtat tagtttgaac aattagaaca
    16561 taacatcttg gtaatttaga tatagtaagg aagagaatcc tttttatgaa agaacgcact
    16621 attatatttg gaaagattaa gttcctaatc tatcatatat aatagtgcgt tatatattta
    16681 agtatgtttt atataaacta atctaaaaat cgaaaatctt tatacaattt ctacttataa
    16741 attgccttta tagggtctag tttagaagct ttaaaggctg gaatcagacc aaatacaact
    16801 ccagtcaata tagtagctac aattgcataa aataagctat ttaagctagg tatagcttca
    16861 aaacctatat atttagaaac atagttagta gcagcaaatc caactatagt tcctaaaatt
    16921 ccaccacata ctgttataaa aacagcttca actaaaaatt gaaataatat agacctaggt
    16981 tttgctccaa tagcacgtct tataccaatt tctctttgtc tttccataac agatacatac
    17041 attatattca ttacaccaat accaccaaca aacattgcaa ctacagttat tatagataca
    17101 tatttgttta cattggaatt aatgctttca agataagctg tctgttcagt tgggtctggt
    17161 gtagtataag aaccattgat accagggtgc atctcatata atttagctat aacattgttt
    17221 gcaacttcat ttacattata gcctttagaa gaaactaagt ctaactggta aatttcattt
    17281 gaataagaat tttgactcat taaagtgtca aaagcctttt taggtactag ggaagtagta
    17341 aattgcatat cttggtaacc tccaaagaat cctccagctt ggttttgctg agaatcatct
    17401 aataccccta ttatttcaaa tatagttcca tttatgttga taccatgacc taaggcatct
    17461 tctggatttt caaaaatttc acttgtactt tgtaatgtaa gtaaaattac ttttcttttt
    17521 tcatcatcta aagaaaaatc tctaccacaa attaaattta ttttagaatc tttttttact
    17581 ggtccaacat caacatacgt agttttttta tcaaaagatg cttgtgaaga gtaaactgaa
    17641 tcaaggttaa acccatctct tgaaggagct attctttcta ctccttcaac aaatgataat
    17701 tcttctaaat cttttgcatt aaagggtttt aaaaaaatac tcatatcatc agtaagacct
    17761 gtgttatcgg ctgattcaaa cgaaatagta gttttattag ggtttacatt gtttacagat
    17821 ttcttaattt ctttttgaaa tccattacct atagaactaa caagtattac tgaagttatt
    17881 cctattataa tccagagtaa agctacaaat acacgaagct tgtgaccttt taaattggcc
    17941 aaagaatttt ttaataaact catgattaca cctccgaagt aaacacacca tctttaagtc
    18001 gtataacctt agttgcatac ttagttaaat cttgatcatg tgtaaccatt attatagtct
    18061 taccttgttt gttgagcctt gttaaaagct ccataatttc tctgctagtt tcactatcta
    18121 atgccccagt cggttcatca gcaaagatta tctgagggtc atttactagg caacgtgcaa
    18181 tggctacacg ctgttgttga ccaccagata attgaagtgg tttctgctta agcttgtcca
    18241 aaagcccaac agaacttaat ttatctttaa caatttcttc tctattagat ttttttagtg
    18301 ctttattgta aattagaggc aactctacat tttgatatac atttagagtt tctattaaat
    18361 taaattgttg gaaaacaaat ccaatattaa tatttctaaa aacagaacgt tcattttcac
    18421 tcaaattagt tacatctgtt ccatcaaata tatatcttcc ttcatcaaat acatctagaa
    18481 aacctaagat attaagtaaa gtagttttac cactaccaga cttacccatt atcatgacaa
    18541 attctccaga ttcaatttct aaatttaagg attttaaaac atgtaattca tctttcccta
    18601 ctttgtaata tttttgaata ttttctaatt taattaacat atgtaaatta attcacatcc
    18661 atagtaactt cttctacttt tttgtttgga gtagtatctc cattattaga accagcagtt
    18721 acgccatcgc cttgaactgg gtctccttct ttcatttctt tagtagggtg ttttattatt
    18781 atatcgcctt gttcaagacc gcctctaact acagcaaaat catcattttg acttgctaca
    18841 tctacaattt gctttttcaa tataccatct aaatccttaa atacatatga gtgtttgttg
    18901 tctttaagta cacaagatgc tggtatttta aagcttgaat tagctacttc aagtgatgct
    18961 tgaagatgga atccatttac taatccttct tgattatcaa atgctatgtt tatatcataa
    19021 taagatagtg tattctgctg agctcccatt tcagtatttg gagtagatgg tttatcagat
    19081 ataaaactta ttctaccagt aagcttttgg tcagttgaaa aaactagtat attgaccatt
    19141 tggtcaatct tcattttagg taaatcttgt tcacttgctt gtcctttcat ataaaactct
    19201 agaccttgaa tagtcataaa tgaaactggt tggtctggat ttccagtttg gtcattcaag
    19261 tatactgtgc catcaaaagg agcagtaact ctgtcataag cttttttatc cagagaagct
    19321 atctgagagt ttaaagcagt tatctgtgca tttatagaag caatagcatc tttattttca
    19381 gcaatatcag aaagtgatat tttttgtttt ttgtattgac taagttgtga ttttaaacta
    19441 tctatttctg ctattatagt tggattttta gcagtaaaaa gaaggtctcc ttgatttact
    19501 ttttgaccat ttgtaacatt aacatcactt aactcataat ctccagatat attgaagtcc
    19561 ttagtttgct taggaacaac catcccattt ataaatattt tttcattttc aggaatagta
    19621 tatgtttcga taaaattttc attagcttgt aattcagtgt ttttcgaatc aacataagca
    19681 agaactccta gaattaaaag tatgattact gctattcctg catatatttt gaatctctta
    19741 tttttaaagg gattgttttt aaaaccttta tttttagact tgaagccact acttccaaaa
    19801 ctgctatttc taaagttgtt acttttaaaa ctgttatttc taaatctttt atttttaaat
    19861 ttttttagaa aagacatgtc ttcctccttt ttataaaaac tacttaatta tatactggga
    19921 tgtacatata gaattactat aagaagttga atataagtta atgaaaataa actatcaata
    19981 ataagatact ataaatcaca tttgaatgta atagtaaatt ttgtatattg gttgtactct
    20041 gaatctacat caattttatg accaagctta tcacaaagtt cttttactaa ataaagccca
    20101 agacctgtag atttagaatt gtttcttcca ttattacctg taaatccctt attgaatatt
    20161 cgatttaaat cttccttttt tataccacaa ccagtatctt ccactcttaa ttgtaaataa
    20221 tttttggttc ttttgcaata gatagatata ttatctccta atgaggagta ttttagggaa
    20281 ttactcaata attgctcgaa tatgaagtat agccattttt catcagataa aaccttaaaa
    20341 ttcaaattat ttaagtctaa aataattttt tttgaaataa aatattttga gtattttttt
    20401 ataatatttc taatgatttt ttcaatattt acctcttgaa ttaaaaaatc cttatgaaaa
    20461 tcttcgagtc ttgataaata taaaattttt tcaacggagt tttcaattct aaatatttca
    20521 ctatctatgt catctgaaat tttttcatta attaaatttt cattttgttc aagaatgagt
    20581 tttattatag ctataggtat ctttacatcg tgtacccaca tatttaaaat ctctttgttt
    20641 tcttcaaatt tctcgatatt attatttatt atgttattac attgatattg atgattttta
    20701 ataatgttca agtatatttt ttcttcattt ttacatctag ctaattctat atcattcata
    20761 ttaattttga atgtatcatt ttttatctta tctaaaaatt tgttcttctt gatgtagcta
    20821 ataaatagat ataaaaataa aaacacaaca tttacaacta atatatataa aatagtatca
    20881 gtcagaaaaa catctacagg agaaaatata ataactgata ctgtaaaaat taagaaagta
    20941 aaattgtata ctaaaaaacc tagtttatcc ttgagaaaat ctttaaagct cataaattca
    21001 cctacttaga attgttttaa ctgattatat aacccaatcc tctttttgtt tctataaaat
    21061 cttctaaacc aatttcattt aattttgagc gtattctatt tacattgaca gttaatgtat
    21121 tatcatctac aaaccaatca ttatcccata attttttcat gagtttattc ctacttacta
    21181 tctgcccctt atatttcata agctcatgaa gaattttgat ttcatttttt gttagctcaa
    21241 tagtattatc ttcatagttt attgttgcag ttgataaatc taaagtaaca ccattgtgaa
    21301 taatctgatt tgagttatta tcaacaaaat tataagttct tcttaaaagg gcattaactt
    21361 tagctactaa gacatctaca gaaaaaggtt tttgtatata atcatctgca cctaaattta
    21421 cacccattat tacatccata ttagaatttc ttgaagaaat aaaaattata ggaacttttg
    21481 aaatttttct tatttcatta caccaatgaa aaccatcata aaatggaagg tttatgtcca
    21541 ataaaactaa ttctgggtta tagtttttga actcttctat tatattttca agattttcta
    21601 tttgatgaac atcatgtccc catttagtaa gacactttgc tatgatattt ttcaatgaga
    21661 cgtcatcttc aactaccatt attttaaaca ttcttacctc ctaattcaaa atagttatat
    21721 taacataact atattctact tgataaatta aaatatttct accttattac ctaaaataat
    21781 tatattaata taactatatt ttacttgata aattatattt taaacataat tgcaataaat
    21841 ttgaagaaat ataattaata cttacgaaaa tgtaacctta aattaatata attaaatgtt
    21901 taaaagccat tttaatatat ataatatatt tgtgagaatt gataaataac taattgtgat
    21961 gaaaggtgat tattaactat ggaagaaata ttatctgttg aaaatataaa aaaggagtat
    22021 ggaagaaaag gttcaaaaca tgaagctcta aaaggaataa ctttcaaggt ttataaagga
    22081 gaatttgttg gtattatggg gtcttccggt gctggtaaat caacactttt aaatattatt
    22141 tctacaatgg atttaccttc atcaggagat atttatataa atggaaagaa tactattaaa
    22201 atgaagcaaa atgaattggc agattttaga cgtgataatc taggctttgt atttcaagat
    22261 tctaatcttt tggatacact tacaataaaa gaaaatataa tgttgcctct ttctttaaaa
    22321 aatgaaagag tatcagtaat agaaaataga ataaaagaga tttcaaaaga attaaatata
    22381 gaatctatat tagataaata tcctggcgaa gtttctggtg gacaaaagca aagaggagct
    22441 gtatgtagag ctatagcaac aaaaccatca ttagtacttg cagatgagcc tacaggagca
    22501 ttagattcta aatctgctag ggatttgttg aattgtctat taaaattaaa caaagacagc
    22561 aataaaacaa tattgatggt aactcatgat gctataagtg cgagtttttg caatagaata
    22621 ctctttataa aggatggaat aatattcaca gaaattgtaa agggagaaag taacagagag
    22681 ttctataata aaatagtaaa tacagtttcc ttaattggag gagttaataa aaatgacttt
    22741 atttagaatt gcaatgcaaa atgtaaagaa tagttttttt aattatttaa tgtactttat
    22801 ttcaattgta tttagtgtat ttgtattttt tagttttaaa tctatagagt ataatgaagc
    22861 gttgagttca cttggagaaa aaactaggat gagtattaat acaagttcaa ttgtaatagt
    22921 ggtatttgta tttttattta tatattattc aaactcattt tttttcaata gacgtaggcg
    22981 agaagtagga acttatagtt tacttggaat gaggaaaaat cagataggaa aaatattttt
    23041 atatgaaact tttttgatgg gtatagttgc aatactaata ggtatatttt taggactgtt
    23101 attttcaaag cttatgacta tgatgcttgt aaaattaatg aatgaaatga tagtagtaaa
    23161 tatgaactta agtataaagg ccttagttaa gacactagcg gtatttttaa taatatttat
    23221 agttattgga ataagaaata ctatagttat cagaaataag agaattatag agttatttaa
    23281 taaatatcca gaaaagtata agtttaaaaa atttataaag ttaaaatgtg tacttggtgt
    23341 tttattaata gctatttctt atttaatgtc aattagttat tttattgctg aaaatattat
    23401 gctttcagtt tttatattag ttacaataat acctggaact tttttatttt tttcatcaac
    23461 tatgtatatg attattgatg ctgttaagaa gagaaaaagt ttttattata agggacagaa
    23521 tttaattgca ttttctgaac ttggatttaa attaaagagc aatagtagtg tattggctgt
    23581 aatagcaata ttaatagcta cgagtgtaac tatgctaggg tttaccatat cactttatta
    23641 cgatatagat aggaacataa gtgaaaatta taaatacagt tataccataa atttaggaaa
    23701 ttcttatgta aataacgaaa ttgacaaatt attatataaa tataaaaaag ataataagat
    23761 aatctttgat aaaacaatag aacttataga caaagatata aatattgaaa tgtattataa
    23821 aaatggaaat agttatatag aagatagaac ttctgtagat attattagag aaagtgattt
    23881 taaaaaatta agacaatatc agaataacaa ttatgaagaa ttaacttcaa aggaatctgt
    23941 gtactatgtt tctgattcat acaaaaaaat gttttttaaa gactttgaga ttgaaaaaat
    24001 aaacttgtat attaaagata caaatgagta tgatataaat ctgtttaagg tacaaaaaag
    24061 catcttggag ccagaaataa attcacaagc tacgtttgat ttaattgtag taaaagatga
    24121 cgtatttaat cagttaaaat tacatggaaa ttctagatta ataagattaa ttgatataaa
    24181 aaatgaaaaa aaagaactgg atttgacttt aaaatttaaa aatatagtaa gtgaaaatat
    24241 gaaatttact tatcctttta attttacatc aagtattgaa agttataata acttgataaa
    24301 attaagtggt ctaatgctgt ttataggcat atttttgtct gtagtatttc ttttatgtac
    24361 aggtagtata atcttattta aacaattatc aaatatatat gatgataagg aaagatatat
    24421 tatgttaata aaacttggag caaataataa agatattgag aaaataatat caaaacagtt
    24481 aaaaattata tttttaatgc cattagttgt aggtacagtt cataatttat ttgctatgtc
    24541 tatagcacaa aagtttatac caaggtcatt acttgtacca attatcataa ctctagtcat
    24601 ttattttata ggatatttta tatattattt tttaacttta aaatatgctc taaacatgat
    24661 aaaagaataa attattttta agtcaaaaga attagatata tgttttgaat aaaataactt
    24721 atttaagtgc agatagaaaa tactagaatt gagtttaaga tatttattta aagataaaat
    24781 taaagttagg aaaaagtcta tattttatat cattttgtat cagttacatt acttgatgtt
    24841 atataataaa tctaagcaga atatcaaata aaaaatgacg aggagctgaa atttatgaag
    24901 tttaatgcct accaacataa atactcatca ataagaaatg tcgtgtatgc taaaaatgga
    24961 gcagttgcaa catcaacacc attagcatct caagctggac ttgaaatact aaaaaagggt
    25021 ggaaatgctg ttgatgcagc agttgcaaca gccgccacat tagcagtagt agaacctaca
    25081 agcaatggga ttggaggaga tgcatatgcc cttgtttgga tagaggaaga aaaacgattg
    25141 tatggtttaa attctagtgg ctttgctcca gaaaatatgg aattaaaaaa ttataataat
    25201 atgaaagaaa tgccaaaata tgggtttgga gcagtaactg tacctggaat acccgcagct
    25261 tggtcagaat taaataaaaa atatggtaaa cttagcttaa tggaatgctt atctccagcg
    25321 ataaactatg caagagaggg atacgtagta tctcctaatg tagctaaggt atggaaaaaa
    25381 tcatatgaac tctatgaaaa agaacttatt ggagaagagt tcaaaccatg gtttgataca
    25441 ttttctaaag atggtaaagc tccagaggct ggagatatat ttatatgtga agaacaggca
    25501 agtacattag aagagatagc aaatactcag gctgaaagct tttatagagg aagacttgct
    25561 gataaaatag atgaatattc taaaaaattt aatggggcta taagaaagag tgacttagag
    25621 tgtttttatc caacatgggt agaacctata agtacagaat ataagggata taaaatattt
    25681 gaaatcccac caaatggtca tggaataaca gttttaatgg cacttaacat attaaaagaa
    25741 ttggaattag aaggaaatat agaaaatgta gaagacatac ataaaattat agagagttta
    25801 aaattagctt ttgcagattc taaaacatat gtaactgata tagagcatat gaaggtaaag
    25861 attcaggaat tactaagcca agagtatgcc aaaaaaagaa gtttattaat tgacaataaa
    25921 gaggctttgt atccaactgc aggagagcca tattgtggtg gtacagtata cctttgtact
    25981 gcagataagg atggaaatat ggtttcatat atacagagca attacataaa ttttggttca
    26041 ggaattgtga taccaagaac tgggattgct ttacatagta gaggaaataa ttttaattta
    26101 gaccctaaac accacaatgt agtaaaacca tttaaaaaac cttatcatac tataatacct
    26161 ggatttttag gtaaagaaga taaagcaata ggtccatttg gtgtaatggg agcttttatg
    26221 caaccacaag gacatattca agtgttaaca aatatgattg attttggatt aaatccacaa
    26281 gaggcgctag atgctccaag atggcagtgg ataaaaggaa aggaaataga agttgaacca
    26341 gagatgccaa agcatataat agattcatta attgaaaagg gtcatgaaat aaaagtaatt
    26401 catgatactg tcgacatggg acgaggtcaa ataatattta aaacagaaca ggaaagttat
    26461 atttgtggga cggaatcaag atgtgatggt catattgcag tttattaata ttatcaacta
    26521 aaatatatat aataaattta aagagtatat gaaataatta gtaaaggcga aagtctacaa
    26581 tgactgacgc ctttacaaaa tttaagctat catatgctga ttttatatag attatgagcc
    26641 ttattcttga ccagttttga tttcattgtc atcataacta atccagtcac taaagctacc
    26701 aatataaatc ttgtgaggta tatccagttc tctaagagca agactgttaa cacaagcaga
    26761 tatccctgaa ccacaagata aaattacttc atcataatta tttaaatctt taaagaattt
    26821 ttttaaaaat tctatatctt taagtgagcc attttcaaag tcacttttta ttaaatcctt
    26881 acaaaaataa ttttttgcac ttggtatatg accagctttt gagtaagcag gttcaactaa
    26941 accctggtat ctctcattag cacggcaatc tattattaca gtatcttttt tgtataattt
    27001 agacttaaca tattccattg gaacaactaa atcattgttt atatttggtc taatttcctt
    27061 acctgtacaa cttggtatat tcactttctc ttccaattct ccaccttcct ttacgaaaga
    27121 tgttattccc ccatctagta catagacatt tttaagcccc aaatgtttta attggaaaaa
    27181 taatctgcaa gctccattta aatctccatc atcataagtt acaatcgtag tgtcattatc
    27241 aacacccatt ttttctaatt tttcttttag tattaaaggg tcttgtaaag gatttttacc
    27301 accatgttct tttgtaggag atgataaatc cttgtctata tctaagataa aactgccttt
    27361 gatatgtcct tttttataag aatcaatacc ataagttcta ttgataagat caaatctgca
    27421 atctattaca actagattat catttttttc tagttttgat ataagttctt ttgctgaaat
    27481 aatgtttttc aaagaatgta cctcctatgt ttatattatc tttattttaa tttatattaa
//
LOCUS       DAMJWO010000057        27117 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.058, whole genome shotgun sequence.
ACCESSION   DAMJWO010000057 DAMJWO010000000
VERSION     DAMJWO010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27117
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.058"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            95..1978
                     /locus_tag="PC366_002452"
     CDS             95..1978
                     /locus_tag="PC366_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2577956.1"
                     /translation="MVLGSKSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTE
                     SYEGTINYNKDPEYLNVWELQGITINSKNNPKTLNKQELEKMGLNLKDYNVTQECIIE
                     DITSRKDVNKYLRKTSAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGI
                     ISTPLATTYNAPILLVEKNNVPNSVKSELKRLNPRDVIIIGDENAISKTTANQIKSTV
                     NASQTRLKGSNRYETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPI
                     ILTDKNSITDNTYKWLKSEDLQNAYFIGGPQMISTNVINKVNDITKDNVTNNRVYGAD
                     RHETNANVIKKFYTDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYH
                     KDNLEAKSANKVYKIGGGLTSKVMNSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGS
                     DTGTTGKPLGGIKEKDYTLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSL
                     RPDLFTSIHYNASDTTGNGVEVFYKLKDKDGGTTKTVATNILNRILEKFNLKNRGAKT
                     RTLSTDPTKDYLYVLRNNDMPAVLVECAFLDNEKDMSLLNTSNKVKEMGTQIGKGIED
                     SLK"
     gene            2491..4503
                     /locus_tag="PC366_002453"
     CDS             2491..4503
                     /locus_tag="PC366_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2577957.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTGAYEGTINYNQDPE
                     YLNVWELQGITINSKNNPKTLNGQDLEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKDSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFY
                     TEDEIEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVY
                     KIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKD
                     YNLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPDLFTSIHYNGSTNK
                     QGHGVEVFYKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVL
                     RSNDMPAVLVECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK"
     gene            4731..6644
                     /locus_tag="PC366_002454"
     CDS             4731..6644
                     /locus_tag="PC366_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577958.1"
                     /translation="MEYLFEKSSLKEYGNEALDKYRELLDKTDNNSRCILLLVPNNNT
                     KIRYERALRLNYSEELKITTYISFVKKELVKYWPLIIEKCDEINTKVVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFEDITGTNKSIANSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNALSIYLYNQYLLNDDFYLKNLFTEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDIDYINEKIISKIK
                     PKEENIKKKEIRIEDLYLLPANIELNQSSQLYNEMLDLISEKVISLIEENVSPRDIAI
                     ISPINNSILEHQIRDSLIEKNIDVFSTKKDKKAVDYPYGNALVVATCIFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNIDEHSQYRDILQYIEEKKKSDIKIHE
                     FLTQFYIDKMLNLKEGKKNVGLCKKIIAESESFSESLSLLRMKKEKIFIEALKSTIND
                     YYSVVDIEELKSKDKIVITTPYSYISSNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEMEEYYKKYYLYNTVYNLLLNAKKIYAFKSEYAINGYIQESILYSI
                     LLKISHKGDKNYD"
     gene            6637..8856
                     /locus_tag="PC366_002455"
     CDS             6637..8856
                     /locus_tag="PC366_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDF2577959.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKGGKILILTYMNSAVNNFKGRIRKILEENKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKSIILNECISRFRFEGGERAFRWFLKEQKDERWKEIALEAWE
                     RGFFEFAGNAISELKYKGISPDKLEEILSRGHKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENKNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVKYVTKEFRQ
                     EECRHALEDMQIKTVPNGMGYKENPNPEHYNINVKWYESWKIEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLTFEELGPNSLNKRKVINNIAYIIDFMLHCDD
                     VEKLIVVLNKVFIDTDNEEEIKYFLEELKNYSTEEIIYNFEFSKLDNDLIEFKEESDI
                     YLSFKRGIDIIKQILEYPIIRLDLLVLFIGKKLNLEKEDKAVLDYISFYIKYLISENI
                     NMDLEDVYNLLFDVKNRVFNHIIDVVYEINGYEPEPGSITLCNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLSRLNQHIIEKRSN"
     gene            8965..9795
                     /locus_tag="PC366_002456"
     CDS             8965..9795
                     /locus_tag="PC366_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HDF2577960.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPLGIYFNEDDKNSKKFLKWMENIKKVVPIEKGKTYL
                     PEYEVRMTLNGDIIQAKYDLVVIGNNNIEIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYDEEKHEANRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            9785..13252
                     /gene="addB"
                     /locus_tag="PC366_002457"
     CDS             9785..13252
                     /gene="addB"
                     /locus_tag="PC366_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HDF2577961.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSNPTENIKIKEFNNLYSEVEEIAREIVHLVR
                     DKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQ
                     ESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIEN
                     LIVNFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDKDILKKITVKSPTFNELINVIKNYDSDDYNTEEINSIWLDIYR
                     YYLKDEIYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGDNG
                     KYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDEDININPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKG
                     LVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRH
                     AIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSTICQFDSTIKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            13252..17079
                     /gene="addA"
                     /locus_tag="PC366_002458"
     CDS             13252..17079
                     /gene="addA"
                     /locus_tag="PC366_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HDF2577962.1"
                     /translation="MSSPKWTKEQLEVIGSRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIANISQACNKSWDEAYKK
                     MASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISSVVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDIDEKGNIVP
                     SDIAVGYRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGANFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKENEIEEEEK
                     LDNIQLEARMVGNIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNETESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLSN
                     LLEEVGLDAVFNVEHNSKWYGKLWNKNDILVEKKSDEEKESIEEILEKIDVDSPDSDY
                     YSEIEKKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            17125..18336
                     /locus_tag="PC366_002459"
     CDS             17125..18336
                     /locus_tag="PC366_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HDF2577963.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITYATQGCTKLNINGENIVIATLPYPSEKRLNEVFSSE
                     DEFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDREIWSYFEINTDEIISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            18323..21850
                     /locus_tag="PC366_002460"
     CDS             18323..21850
                     /locus_tag="PC366_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2577964.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNIQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNIQLQNLKDLKSKLSQYDGITEEVYNNIN
                     QELIELKNLEKDKNNALDLAQKSYEESKTVYEEQLKLEKNELRKNELDLKNSEIKEKI
                     ALVENDSNAKKVDPYISSVQNLEKKIDEDSFVVSNLEKKLAILNQELEVTKNRYEKIN
                     KIKNEEVPKLSEEKIRLQQAIKLEEELVLLDRELKDLKESGINLNKTKVELEKVKQVS
                     ESRKDAVTKSIKEVEGKIDKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKLNKLEEI
                     LKETENINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRS
                     KANNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEELK
                     YLNLASELRRELKENMPCPVCGSKHHENHNITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKVSGYLSIEKMKTKELEDVKGKLGGIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKLKQ
                     EYLGLKTITKVSNLLSKVKEIRENEKELELLSTGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYVEKKLSRDNKYKEVINITKGDLAKNLLHNVEENICKILEQEESSKK
                     KLEEQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     TDAVKKLIEEILEHEEEQKLLSFKIKSSKEKLNGRSIKKEYFEQLKDEIYNLKVEIGN
                     ISKDIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
     gene            21981..23234
                     /locus_tag="PC366_002461"
     CDS             21981..23234
                     /locus_tag="PC366_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDF2577965.1"
                     /translation="MLESPNNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
     gene            23383..24434
                     /gene="ytvI"
                     /locus_tag="PC366_002462"
                     /pseudo
     CDS             23383..24434
                     /gene="ytvI"
                     /locus_tag="PC366_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
     gene            24525..25751
                     /gene="pepT"
                     /locus_tag="PC366_002463"
     CDS             24525..25751
                     /gene="pepT"
                     /locus_tag="PC366_002463"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HDF2577966.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPRIIENYDGKD
                     IVLNEALNVITYVKDSPELEEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFDVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIAAEISEMFPADERPETTEGYEGFWHLNSIGGNVENVS
                     MAYIIRDHCREKFENRKSIMIENIEKINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELGIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            25958..27010
                     /locus_tag="PC366_002464"
     CDS             25958..27010
                     /locus_tag="PC366_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HDF2577967.1"
                     /translation="MKIKSKKIIAFALSLGIMLPSCVYADTISKNQNAQVDMNNYLQG
                     RKSPKEEKLIGEDRFDTAIKISQSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVTEEIKRLNPAEVILIGSEGAISSSVKESLEDMEVLVSRIGGADREE
                     TSLLLTRQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTKTYIVGGEYSISKKLEGQLVNSERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
BASE COUNT        11549 a         2653 c         4807 g         8108 t
ORIGIN      
        1 aatggcaatc gtcgcaccta caatggcatt tgctactgaa tctaatgcta tggaaaataa
       61 cgctgattta aatataaact tagagaaaaa aagtatcgtt ttaggtagca aatcaaaagt
      121 cagtgtcaag tttaaagaaa aaccagatgc agatagcatt acattaaagt ataaatgcta
      181 tgatatgcca ttggatacaa ctctaaatta taatcaatca actgagtcat atgaaggaac
      241 tatcaattat aataaagacc cagaatattt aaatgtttgg gaactacaag ggataacaat
      301 aaacagcaaa aataatccta aaactttaaa caaacaagaa ctagaaaaga tgggattaaa
      361 tttaaaagac tataatgtaa cgcaggaatg tataattgaa gatataactt ctagaaaaga
      421 tgtaaataaa tatttaagaa aaacttctgc acctattaca gaacttacag gaagtgatag
      481 atacgaaaca gcagttaaaa taagtaaaga aggctggaaa aatggttcag ataaggtagt
      541 tataataaat ggggatgtaa gtatagatgg cattatatca actccactag caactacata
      601 taatgctcca atacttttgg ttgaaaaaaa taatgtacct aatagtgtaa aatcagaatt
      661 aaagcgttta aatcctagag atgtaattat aattggagat gagaatgcta tttctaaaac
      721 tactgctaat caaattaaat cgactgtaaa tgctagtcaa acacgtctaa agggctctaa
      781 tagatatgag acatctttat tgatagcaaa ggaaatagat aaaaatcatg atgtggaaaa
      841 agtatacata acaaatgcta atggcggaga agtggatgca cttactatag cagcaaaagc
      901 aggtcaagac aagcaaccaa ttatattaac tgataaaaat agtattacag acaacacata
      961 taaatggtta aagagtgagg atttacaaaa tgcttatttt ataggtggac ctcaaatgat
     1021 atcaacaaat gttataaata aggtaaatga tataactaaa gataatgtta ctaataatag
     1081 agtatatgga gcagatagac acgaaacaaa tgcaaacgta ataaaaaaat tctatacaga
     1141 tgatgagtta gaggctgttt tagtagctaa atcagatgta cttgttgatg ctttagcagc
     1201 aggtccattg gctgcgaact taaaatctcc aatacttata acaccaaaga cgtatgtatc
     1261 tgcataccat aaagataatt tagaagctaa atcagctaat aaagtatata aaataggagg
     1321 aggattgact tctaaggtaa tgaactctat agcatcatca ttatctaaac acaatacaac
     1381 tccaacagaa ccaggaaata gtgggggtaa gacagttatg attgacccag gacatggtgg
     1441 ttcggacact ggaacaacag gtaaaccatt agggggtatt aaagaaaaag actatacatt
     1501 aaatacttca cttgcgacaa ctgaatattt acgttcaaag ggattcaatg taataatgac
     1561 aagagacaca gataagactt tatctcttgg aaatagaact gctttatcta actctttgag
     1621 accagattta tttacgagta tacactataa tgcatctgat acaactggga atggtgtaga
     1681 agtattttat aagcttaaag ataaagatgg agggactact aaaactgtag ctacaaatat
     1741 attaaataga atcttagaga aatttaatct aaaaaataga ggtgcaaaaa caagaacact
     1801 atcaactgac cctacaaaag attatttata tgttttaaga aataatgata tgccagctgt
     1861 acttgtagaa tgtgcatttt tggataatga gaaagatatg agtttactta atacatcaaa
     1921 taaagtaaaa gaaatgggta cacaaatagg taaaggcata gaagattcat taaaatagtc
     1981 tacaatgaga gcatagaaaa atttaaaata aattaatctg caattttaaa tttaaactaa
     2041 agctataaga taagaatgta attataatag taataaagac tgtatataca ttgtgcatat
     2101 aagtgcgaaa tgaggtatat acagtctttt tatgattaat tgtaaaagga tttatattat
     2161 atgaagaatt tacatatctt aaggctacag ttaattgtca agagttggag tattcatttg
     2221 taatacacaa taaaagctta attactatat tttattgtgt gtttgtgtgt ttgtgtgttt
     2281 tttgtggatt tttatgtcaa taaatgatat agtatagata attaaatgta ttaaatatat
     2341 ttaatttttt tattttttga gttttataag tttattttta tatattactt atatattatt
     2401 tatattttgg gttagataca ctttgacata ttttcaaaag ttaaaagatt aaaaataaag
     2461 tagaaattta tgttaagtaa ggagattaat atgagaagaa atacaaaatt attaacaaca
     2521 gggattcttt caatggcaat cgtcgcacct acaatggcat ttgctactga atctaatgct
     2581 atggaaaata acgctgattt aaatataaac ttagagaaaa aaagtatcgt tttaggtagc
     2641 aaatcaaaag ttagtgtcaa atttaaagaa aaaccagatg cagatagcat tacattaaag
     2701 tataaatgct atgacatgcc attggataca actctaaatt acaatcaatc aactggggca
     2761 tatgaaggaa ctatcaatta taaccaagac ccagaatatc taaatgtttg ggaactacaa
     2821 gggataacaa taaacagcaa aaataatcct aaaactttaa acggacaaga cctagaaaag
     2881 atgggattaa atttaaaaga ctataatgta acacaggaat gtataattga agacataact
     2941 tctagaaaag atgtaaataa atatttgaga aaaacttctg cacctattac agaacttaca
     3001 ggaagtgata gatatgaaac agcagttaaa ataagtaaag agggctggaa aaatggttca
     3061 gataaagtag ttataataaa tggagatgta agtatagatg gcattatatc aactccgctg
     3121 gcaaccacat ataatgctcc aatacttttg gttgaaaaaa acaatgtgcc taatagtgta
     3181 aaatcagaat taaagcgcct aaaccctaaa gatataatta taattggaga tgagaatgct
     3241 atttctaaaa ctactgctaa tcaaattaaa tcgactgtaa atgctagtca aacacgttta
     3301 aatggttcta atagatatga gacatcttta ttgatagcaa aggaaataga taaaaatcat
     3361 gatgtggaaa aagtatacat aacaaatgct aatggcggag aagtggatgc acttactata
     3421 gcagcaaaag caggtcaaga caagcaacca attatattaa ctgataaaga tagtattaca
     3481 gacaatacat ataaatggtt aaagagtgag gatttacaaa atgcttattt tataggtggt
     3541 cctcaaatga tatcaacaaa tgttataaat aaggtaaatg gaataactaa ggatagtgtt
     3601 actaataata gagtatacgg agcagataga cacgaaacaa atgcaaatgt aataaaaaaa
     3661 ttctatacag aggatgagat agaggctgtt ttagtagcta aatcagatgt acttgttgat
     3721 gctttagcag caggtccatt ggctgcgaac ttaaaatctc caatacttat aacaccaaag
     3781 acgtatgtat ctgcatacca taaagataat ttagaagcta aatcagctaa taaagtatac
     3841 aaaataggtg gaggattgac ttctaaggta atgagctcta tagcatcatc attatctaaa
     3901 cacaatacga ctccaacaga accaggaaat agtgggggca agacagttat gattgaccca
     3961 gggcatggtg gttcagcacc tggaaattca tctggaggaa tgattgaaaa agattacaat
     4021 ttaaatactt cacttgcaac aactgaatat ttacgttcaa agggattcaa tgtaataatg
     4081 acaagagaca cagataagac tttatctctt ggaaatagaa ctgctctatc taattcattg
     4141 aaaccagatt tatttacaag tatacattat aatggctcaa ctaataaaca aggtcatggt
     4201 gtagaagtat tttataagct taaagataaa aatgggggga ctactaaaac tgtagctacc
     4261 aatatattaa atagaatttt agagaaattt aaacttacaa atagaggtat aaaaacaaga
     4321 gtacttccta gtgattctac aaaagattat ttatacgttt taagaagtaa tgatatgcca
     4381 gctgtacttg tagaatgtgc atttttggat aatgaaaatg atatgagttt aataaactca
     4441 tctgcaaaag taaaagaaat gggtacacaa ataggtaaag gaatagaaga ttcattaaaa
     4501 taaatggaaa taaaaatatt taaaaactta atgtaaattt atactaaagt caaaaaatga
     4561 aatataagtg tatcaatagt aagactgtat gtacatttgc acatgtgaat gcaagtatat
     4621 atacagtctt tttttgtagt taaatgcaat aatttgattg tgttttgtaa aatacacaat
     4681 atgatataat tagataatat acacttaatt taattgagga aggtgattat atggaatatt
     4741 tatttgaaaa aagtagttta aaagaatatg gaaatgaagc tttagataaa tatagagaat
     4801 tattagataa aactgataat aattcaaggt gtattctttt attagtacca aacaataaca
     4861 caaagatacg atatgaaagg gctctaagat taaattatag tgaagaactg aaaataacaa
     4921 catatataag ttttgtgaag aaagaattag ttaaatactg gccactaata atagaaaaat
     4981 gtgatgaaat aaatacaaag gttgtatctc caacatttat atcaaatagt ttaagtgaat
     5041 atttaatagt gcaaaaagtt aaggaaaaaa ggatacaaga aggatatttt gaagatatta
     5101 caggaaccaa taaatccata gcaaatagta taatgactaa cataaataaa tctgcattta
     5161 atttaattga ttttgatttt attggagaaa aaatatattc atcaaagaaa aataaagata
     5221 gtatatatag attttcatac actcagatgg atgaaattat atcatattat ataaattcgt
     5281 tactatcaaa ttcaatttta gataatgcat taagcatata tttatacaat caatacctac
     5341 ttaatgatga tttttattta aaaaacttat ttacagaagt gagatatata attgtggata
     5401 gtcttgaaag ctcaagtaat gcagaagttg attttataac agaagcattg gataatacat
     5461 tacaaagtta tatatatttt gattatagta gggattattc tgtatttaat aatgtggata
     5521 tagactatat aaatgagaaa ataatatcaa aaattaagcc taaagaagaa aatattaaaa
     5581 agaaggagat tagaatagaa gatttatact tattacctgc aaatatagaa ttaaatcaat
     5641 caagtcaatt atacaatgaa atgttagatt taataagtga aaaagttata tctcttatag
     5701 aagaaaatgt atctccaaga gatatagcaa ttatatctcc tataaacaat agtatattgg
     5761 agcatcaaat tagagattct ttgatagaaa aaaatataga tgtttttagt actaagaagg
     5821 ataaaaaagc tgtagattat ccatatggga atgcattggt agtggctaca tgtatatttt
     5881 atggatattt agattttata aaagatgatg aatacttaag ctttttagaa actcttttag
     5941 aaataaatag gataaaagca tttaagattt ttaatgaaac aagacattta agtattgata
     6001 atatagatga acatagtcag tatcgtgata ttttacagta tattgaagaa aaaaagaaga
     6061 gtgatataaa aatacatgaa tttttaactc aattttacat agataaaatg ttaaatttaa
     6121 aagaaggtaa aaagaatgtt gggttatgta aaaagataat agctgaaagt gagtctttta
     6181 gtgaaagttt aagtctactt aggatgaaaa aagaaaagat atttatagaa gctttaaaaa
     6241 gtacaataaa cgattattac tctgttgtcg atatagaaga gttgaaatcc aaagacaaaa
     6301 tagtaataac tactccttat tcatatatat catcaaatat agatagaagt atacaaatat
     6361 gggtagatat aggaagtaat gcttggaata tgaaaataga aaaagatata agtaatttaa
     6421 ttgtacttag aaaatctttt gaagaaaaaa agatttatac aaatgaaatg gaagaatatt
     6481 ataaaaaata ttatctatac aatacagtat ataatttgtt attaaatgca aagaaaatct
     6541 atgcatttaa aagtgaatat gcgattaatg gttatatcca agagagtata ttatatagta
     6601 tacttttaaa aatctcacat aaaggagata aaaattatga ttaatataaa ttatagagaa
     6661 gaccagatac caataataaa ttacgataat ggtactatgg cagtaccagc agtaccaggt
     6721 gctggaaaaa catttataat aacaaattta gtagctaaac tattacttga acagaaacat
     6781 aagggtggta aaatattaat tcttacatat atgaatagtg ctgtaaataa ttttaaaggt
     6841 agaataagaa agattcttga agagaataaa atagatgata ctaattcgta tgaagtaatg
     6901 actatacaca gtttggctgt aaaaataata aaggaaaagc cagaagttgt aatgttaagt
     6961 gaggatttta acatagctga cgatttgcaa aaaagtatta tattaaatga atgtataagt
     7021 agatttagat ttgaaggtgg agaaagagct tttagatggt ttttaaagga gcaaaaagat
     7081 gaacgctgga aagaaatagc tcttgaagcc tgggaaagag gtttttttga atttgcagga
     7141 aatgcaataa gtgaacttaa gtataaggga atttctccag ataaacttga agaaatattg
     7201 tcaagaggac acaaaggaat gcttaaaatt attttaccaa tatataaatt gtatgataga
     7261 aaattaaagc aaaatggatt gctagattat gatgatatat taattttagc agaaaaaact
     7321 ttaagcttag acgaagggct tagaaagaag tttcaaacta gatacaaata tatatttgaa
     7381 gatgagtgtc aggactcaaa tgaaattcaa ggtaatataa taaaaattat atctagtgaa
     7441 aataaaaacc tagttagagt tggagatata aatcagagta taacaggaac attttcatca
     7501 tcagacccta aattttttaa agaatttata aatagtgcag atttctgtta taggatggat
     7561 atgtcaaatc gaagttcaaa agatatactt gatttagcaa acactcttgt caagtatgtt
     7621 acaaaggaat ttagacaaga agaatgtaga catgctcttg aagatatgca aataaaaact
     7681 gtgccaaatg gaatgggata taaagaaaat cctaatccag aacattataa tataaatgta
     7741 aagtggtatg agagttggaa aattgaaata gagcaaactg ctagatacgt taagggtata
     7801 aaaaataaat atccagataa aagtataggt atattggttc catttaatga acaagtgaca
     7861 caagttgcta aagaacttag agagaataat ctaacctttg aagaattagg accaaattct
     7921 ttgaataaaa ggaaggttat aaacaacata gcatatatta ttgattttat gttacattgt
     7981 gatgatgtag aaaagttaat agttgtactt aataaagttt ttatagatac tgataatgaa
     8041 gaagaaataa agtatttttt agaagaatta aaaaactatt ctaccgaaga aattatttat
     8101 aattttgaat ttagtaagtt agataatgat ttaatagaat ttaaagaaga aagtgacata
     8161 tatttaagtt ttaaaagagg aatagatatt ataaaacaga tattagaata tccaataata
     8221 aggttagacc tcttagtttt gtttattggg aaaaaactta atttagaaaa agaagataaa
     8281 gctgtactgg attatatatc tttttatata aagtatctaa tatcagaaaa tataaatatg
     8341 gatttagaag atgtatataa tttattgttt gatgtaaaga atagggtgtt taatcatata
     8401 atagatgtgg tatatgagat aaatggatat gaaccagagc ccggtagtat aacactatgt
     8461 aactatcata agtcaaaggg gatggaatgg gattgtgtgt ttttactagg tcttgttgaa
     8521 tataatttcc ctgacaatat taatcaaaag tttcagagtg ataaatggta tctaaaagaa
     8581 aaatataaaa accctatggc aattattaaa tcagaagttg aagctatatt aaaaggaagt
     8641 atttcaacag attatgctca taaaacgaag attgattcta taaatgaaaa gattagactt
     8701 ttatatgtag ggattactag agcaaaggaa atgttagtac tttcaggaag tgcttataga
     8761 gatgaaagtg atatagggaa taagagaaaa gagcaaaaac catgtatata tttaagcaga
     8821 cttaatcaac atattattga aaaaaggtca aattaatata taataagtta ttaaaagatt
     8881 gcttgaaata tatctaaaag gggataaaac aatatgtaca gtaagtaact actaaaaaat
     8941 aaagttaaga gagaagtgat atgagtgaac gataaattaa aatatttttc ttatagtcaa
     9001 aattcaatca acacatataa atcatgtcca ttgaaattta aatataaata tattgataga
     9061 ataaattgga aaaatgatga tgttggtagt agagagtatt atgaaacttt aaaaacagga
     9121 agagattttc atttgatttg tgaaagatat tttagcaata tacctcttgg aatctatttt
     9181 aatgaggatg ataaaaatag taaaaagttt ttaaagtgga tggaaaatat aaaaaaagtt
     9241 gttcctattg aaaaaggaaa aacgtatttg ccagaatatg aagtaaggat gaccttaaat
     9301 ggggatataa tacaggcaaa gtatgattta gttgtaattg gaaataacaa tatagaaata
     9361 tgggattgga aaaccgagtc taaaaagatt gactataaac acgtagaaaa tagaatacaa
     9421 actattgttt atatgttttt agcaaaagaa gtaataccta aagttttaaa aatggacata
     9481 aatgttaaag atataaatat gagatattat caacctgaat ttgatgactt accaattacc
     9541 attttatatg atgaagaaaa acatgaagca aatagaaata aaattcaaaa ttatataagt
     9601 atgataaaaa acactaatta tgaagaacat acatacgaag acaatctata caatgatata
     9661 gaaaaggtat ataataaaga agaacgtatg tgctatagaa ataaaaagca ttgcaagtat
     9721 tgtgaattta ataagttatg taatggcaaa gaaatagatt atagtatttt ggaggcggaa
     9781 atttatggga cttaggtttg tattaggtag aagtggaagt ggaaaatcca cctatatact
     9841 agatgagatt aaaaaagaag ctcaaaaaaa tgaaacgaca tcaattatac ttttagttcc
     9901 agaacagtac acatttgagg ctgaaaatag agtaagtaag ctattcttag gaaaagaaaa
     9961 agataagtat ctaagagtta gggtacttag ctttaagaca ctaagtaata tagttttttc
    10021 tcaagtagga ggattgacag atgtaaatat aaattctagt ggaaaagcaa tgatggtata
    10081 tagagctatt gaagatgtaa gtgaagaatt aaatgtgttt tcaaaatcaa aatcgcagtc
    10141 tggttttgta agctcaatta cagatatgat atcagaaatg aaacaataca atataagccc
    10201 tgaaatgtta gaaaatatat ctggagaatt ggataatgaa actttaagtt taaaattaaa
    10261 agatataagt aaaatatata attcttttga agggaaattg catgaaaatt atgtagatgc
    10321 tcaagatatg ttaacttcat tggcaagtaa aattgaatta agcagttatt tagatggagc
    10381 ttgtgtttat atagatgaat ttacaggttt tacaccaaat cagtacaatg tcataaagag
    10441 tatattaaat aagtctaaaa gtgttaatat ctctttgact gtagatgata tcaactatat
    10501 tgggtacagt aaatctgata tgttttctag aacgaaattt acttattcaa aattgactca
    10561 attgtgcaac gaagaaggca taaaaatatt gccacaagta aatttaaaca caggtgttat
    10621 aaaaagattt gaaaaagtta aggaattaca gcacctagaa agattttata atgcttatcc
    10681 atataaaata tattcaaatc caactgaaaa tataaagata aaagagttta acaatttata
    10741 ttcagaggtg gaagagatag ccagagaaat tgtacattta gttagagata agaatgtaag
    10801 atatagagat ataaccattg ctacaagaga tttaaataga tatgattttt tagtacactc
    10861 tatatttaat gaatataata taccaaactt tatagataag aagagagagg caaaaagtaa
    10921 tccaatagtt attttaatta tttcagcttt agaaatgaag aatagacgat atgggtatga
    10981 aactatgttt aggtatttaa aaagtggact tataggaatt gataatgatg atataaattt
    11041 actagaaaat tatgtgttgg ctaatgggat taaaggtaaa aaatggtttg atgaaaaatg
    11101 ggattataga ataacacaaa gtctttcagg tcaagaaagt gaatttgaac tggaattaaa
    11161 agaaaaaata aatgaaataa aaaatagagt attagagcct atagtaattt tacaagaaaa
    11221 attaagagga aaaaatagag taaaagaaat ctgtagatat atatatgaat ttttattaga
    11281 tataaatatg ccagaaacta tagaaaattt aatagtaaat tttaaggata aaggggaact
    11341 tgatgttgca aatcaatact cacaagtttg ggacatagta gtggacatat tagaccaaat
    11401 ggtggaactt atgggtgatg aaataatttc tttagaaaaa tttataaaat taataacctt
    11461 aggctttgat gaatatgaat taggactggt tcctcctagt atagaccagg tacttgtaag
    11521 tagtgtggat agaatgaaaa atccagacac gaaatattta tacctagttg gaactactga
    11581 tggtgtgttt ccactgatta caaaggatag tggaatattg agtgataatg atagggaaag
    11641 tcttggaaac aaaggaatcg aagttgatat tgatagtaag actaggagtt ttgaagaaca
    11701 gtttcttgta tataaagctc ttacttcgac atctaagaat ttaaccataa catatccaat
    11761 atcagaccat gaaggtaaaa cgcttagacc atcaataatt atatcaagac ttaagaagat
    11821 atttccaaat atagaaaata aaagttattt agtggaagaa aataaaagca ctgataaaga
    11881 tatacttaaa aaaataacgg ttaaatcccc tacatttaat gaacttataa acgtaataaa
    11941 aaattatgac agtgatgatt acaatacaga agagattaat agtatttggt tagatatata
    12001 taggtactat ttaaaagatg aaatctatag ttctataaca aaaaaagtta taaaaggtct
    12061 tagttatact aatcaagttc ataagattga agagaaaaaa ataaggtcat tgtataaaag
    12121 taattctctt agcatatcta ggcttgaaaa atatgctgaa tgtccatttg cttattttat
    12181 acaatatggt ctaaaagcaa aaaagcgtaa agagtattca tttacaccac cagatttagg
    12241 aacttttatt cataatattt tagataggtt ttcaaaagaa cttttacaag ataatttaac
    12301 ttggagagat attgatgaaa aatatataga attaaagata ggtataatag ttgatgaaat
    12361 aattttaaag ataccaggat atatattaaa tagttctgag aggtataaat accttgcata
    12421 tagattaaag aatatgttga caactgctat aactataatt agtcagcaaa taaaacaagg
    12481 ttcatttgaa ccaatagatt atgaagttaa atttggcgac aatggaaaat atccacctat
    12541 aaaaatggtg ttagaaaatg gacaagaagt aagtttaatt ggacaaatag atagagttga
    12601 tgaatttgaa gaaggagaaa ataaatatat aagaataata gattataagt caggcaataa
    12661 gtccataagt ctaacagaaa tatattatgg tctacaatta caattacttg tgtatttaga
    12721 tgcaatcctt gaaagtgcaa aggatgaaga tataaatata aatccagctg caatactata
    12781 ttgtagaata aataatccaa tagcaaaatt taatgaagat aaagatgatg aagaaataca
    12841 agaagcaata ttaaaagaac ttagaatgaa ggggcttgta gtaaaagact ctcacatagt
    12901 taaagagatg gataaatcat taatagatgg agaaaggaaa aactctttag taataccagt
    12961 aggtcttact aaggatggaa atgtaggtaa aagtacttca gcaataagct atgaggattt
    13021 caaactgctt agaaaatatg taaggcatgc tataaaggat ttatgtgaag aaatgttaag
    13081 tggagaaata cgtatagctc catataaaca taaagatgga acatcatgtg acttttgtga
    13141 ttactctact atatgtcagt ttgattcaac tataaaagat aacaagtata aaaatttaaa
    13201 taataagagt aatgaagaga taataaaaat gatgaaagga gatgttaatt agtgagttct
    13261 cctaaatgga caaaagagca attagaagtt ataggaagta gagaatgcaa tttattggtt
    13321 gctgctgctg ctggttcagg aaaaacagcc gttctagttg agcgtataat tcaaatgata
    13381 acaagtagag aaaatccaat tgatatagat aagttattag ttgttacatt tactaatgct
    13441 gctgcgtcag aaatgagaga gaggataggg gatgctatag gaaaagcctt agatgaaaac
    13501 ccagaaaata aacatttaca aaaccaactt gttttattaa ataaatctag tattacaaca
    13561 atacactcat tctgtttgga tgttataaaa tcaaactttc atagaataaa cttagaccct
    13621 aatttcagaa taggagacca aactgaatgt gctattttga aacaagaagc aatagaggaa
    13681 gtatttgaag atttatatga agaaagagat gaggggtttt taaatttagt tgaaagttat
    13741 gcagaaagag gaggagataa agaagtacaa gatattatct tgggaatata ttcatttgca
    13801 atggcttctc ctgaacctaa aaaatggttg attgactcag cagaacgatt taatattgat
    13861 gaaaattttg atttttcaca gtctatttgg gctagagcta tattagacac tgtaaaaata
    13921 gaaattaatg gtctttgtct aaatatggaa agggcattaa aagaagtgga atcaatagaa
    13981 gaattagaaa cttttgcaga aaagttatcc gttgaatata aaaaaattgc taacatttca
    14041 caagcatgta ataaatcttg ggatgaggca tataaaaaga tggcaagtat gtcctttgaa
    14101 aattatgtaa aaggagtaaa aagaatttca aaagatgctc cttcgtatat aaaagaatca
    14161 aaagaaaagg caaaaactat aagagataag actaagaagt ctttagaaag tatagtaagt
    14221 gctacattca ataaagataa tgattctatt agagaagaaa taaaatatct ttataacata
    14281 gttaaaccaa tatctagtgt tgtactgaga tttgaagagg aatatagcaa taagaaaaga
    14341 gaaaaaggaa taatagattt taacgatata gagcattttg cattaaatat acttacagat
    14401 atagatgaaa aaggtaatat tgtaccttct gatatagccg ttggatatag aaacaagttt
    14461 tatgaaatat ttatagatga atatcaggat agtaatctag tgcaggaagt actgcttaaa
    14521 gctgttgcaa atacagaaac tccaaataga tttatggttg gtgatgtaaa acagagtata
    14581 tatagattta gacaagcaaa gccagaatta tttttgcaaa aatataataa ctataatgat
    14641 aaaaagggaa gttcccatag aaaaataatg ctttacaaaa attttagaag tagagaagaa
    14701 gttgtagatg ctgtaaatta tatatttgaa aatataatga atgagaatat aggagaaatt
    14761 gaatatacag aaaaagaaag actaaattta ggtgcgaatt ttaatgtgga tacagacgag
    14821 aaatctatta ttggtggagc aacggagata cacctaatac aaaaagataa taaacttgat
    14881 gatgatatta taaatgataa agacgataga attaataaca aagaaaatga aatagaggaa
    14941 gaagaaaaat tagataatat acaacttgag gctagaatgg ttggaaacat tatcaaagat
    15001 ttaatgaaag tcaatgaaga tggaaaaatt caaaaggtct atgataaggg aatagatgga
    15061 tatagacctg tggaatttag agatatagtt attcttttaa gagctacatc tgcatgggct
    15121 ccagtgtttg cagatgaatt gatgaatatg gatataccaa catatgctga tgttggagtg
    15181 gggtattttg atacgattga aataaaaaca atattgtcat tacttcaaat aatagataat
    15241 ccaatgcaag atatacctct tatatctgta ttaaaatcac ctatatttgg atttacacca
    15301 gaggatttga ttgatattag agttcagagt aaagataaaa ttttttatga ggttttaaaa
    15361 agtacagcag agtatgatgg atttacagat tctcaaaatg aaactgagtc tgagtttata
    15421 ccaagtgaag agtgcataaa caaaagtaaa gattttttaa ttaagctaaa ggaatttaaa
    15481 gaaaagtcaa tgtacatgag tacagatgaa tttatatggt acttgtacac aaggactgga
    15541 tactatgctt atgttggagc attgccaggt ggaagtcaaa gacaagctaa tttaaaagta
    15601 ttgtttgaga gagcaaaaca atttgaagaa accagtctta aaggaatatt caactttgta
    15661 aattttatag agaaattaaa aaaatctagt tctgatatgg gaagtgcaaa aacacttggt
    15721 gagaatgcaa atgttgttag aataatgagt attcataaaa gtaaaggtct agaatttcca
    15781 gtagtcatat gctctgcaat gggtaaaaat ttcaatactc aagattttaa aaagagtatt
    15841 ttatatcatc ataatttagg gtatggacct caatttgtag actatgagag aaggatttct
    15901 tttccaagta tagccaaaga agcattaaaa agcaaaataa atatagaaaa tttatcagaa
    15961 gagatgagag ttttatatgt tgcatttaca agagctaaag aaaaattgat tataactggt
    16021 tctactagaa atatacaaga tagtataaag agatggtcaa atggaattga aagtttagat
    16081 acaatatcac aatacgagat attaaaaggt aaaaattttt tagattggat aatgccttgt
    16141 gtattaagac atagggattt atctaatcta ctagaagaag taggattaga cgcagttttt
    16201 aatgttgaac ataattcaaa atggtatgga aagttgtgga ataagaatga tattttagtg
    16261 gaaaagaaga gtgatgaaga aaaagaaagt attgaagaaa ttcttgaaaa aatagatgta
    16321 gatagtccgg acagtgatta ttacagtgaa atagaaaaaa aattaaacta tatatatcca
    16381 tatgaattta gtacaagaaa acctgctact atatctgtta cagaaataaa aaagatacaa
    16441 aataattatg aagaagagtt aataaatact atatttgaac aaaaagtaat attaaaaaag
    16501 cctctattta ttcaaaatga agaagaaaga gaaaaaataa gtggaacaga aagaggtaca
    16561 atagtccatt tggttatgga ggttttagac ttaaaaaatg taagtagtgt aaatgatata
    16621 aaatcacaaa taagaggttt tgtttcaaaa ggtataataa cagaaaaaca agctagtata
    16681 gtaaatccat ataaaatata taaatttttt gcctctaaca taggaaaaag aatgttgaat
    16741 gctgaaatta taaatagaga aaaatcaatt tatgcacaag taaatatgaa agacatatat
    16801 atttatgaaa agcttataaa caatgatgat aaaaaacttt atgataatga aagtgtcatg
    16861 ttaagaggta tagttgatgc ttattttgaa gaagataatc aaatagtttt ggtggattat
    16921 aaaacagatt ttgtaaatga ggaaaatata aatcaaataa tagagaaata taaaaaacag
    16981 ttggatttat atgcagatat tattgaaact ttaactggta agtcagtaaa agagaaatgt
    17041 atatatttat ttggagttga tgaagctgtt tgttattagt ttttatatat aaattaaacc
    17101 taaaagatag aggaagggga aaaaatgaga tttattcata catcagattg gcatctaggg
    17161 aagtccctag aaggccattc tagaattgag gaacaagcaa agttttgtga ggaatttata
    17221 aaaatagtag aatcaaatga aatagatatg gttataattg ctggagatgt atatgatact
    17281 tctaatcccc cagcacaagc agaaaaacta ttttatcaga ctgtatcaag acttgccaat
    17341 aatggtcaga ggtgtgtatt aataatttca ggaaatcatg ataatccaga gagactttct
    17401 gcaataacac ctctagcaca tgaacagggg atacttatat atggttatcc attaagtgct
    17461 acgatagaag ctaagtataa agggtttgaa ataacatatg caactcaggg atgtacaaaa
    17521 ctgaatataa atggagaaaa tattgtgatt gctacattac cttatccaag tgaaaaaaga
    17581 ttaaatgaag ttttttcaag tgaagatgag tttgagaaac aaaaaaatta ttctgaaaag
    17641 gtaggagata tatttagaag tttagaagaa aattttagaa gtgatactat aaatatagcc
    17701 gtatcacata tatttgtaat aggtggagag agtactgaat cagaaagacc tatacaatta
    17761 ggtggaagtt ttttagttga aagaaaagat ttgccagaaa aggctcaata tactgcacta
    17821 ggtcatttac ataaacaaca aaaagcttcc gaacgtttaa atgcatacta ttctggttct
    17881 ccacttcaat atagcaagga tgaaagagcg tataccaaag gggcatacat agtggatata
    17941 aaagctggag aaaaaccaat aattgaagat gtatatttta ataattacaa acctatagaa
    18001 gtatttaaat gtaatggaat agaagaagca ctagatatat gtgagcaaaa tcaagataga
    18061 gagatttggt catattttga aataaatact gatgagataa tatcacagaa tgaaattaaa
    18121 aaaatgaagg aactattaaa agacataata gaaataaaac caataataac atcttgttat
    18181 gaacaagaaa gtgtagatat aaaagaaaag tctatggcag agttgtttag agagttctat
    18241 tcttttagta aaggtgtaga gccaaaagga gaacttatgg atttatttct agatataata
    18301 agtgaagaag gtgaatcagc agatgagacc aattagatta gaacttacag gacttaatag
    18361 ctatattgat aaacaagtta tagactttga aaaattaatt gaaagaggtt tgtttgggat
    18421 atttggaact actggaagtg gaaaatctac aatcttagat gcaataacta ttgctatgta
    18481 tggaaatata tccagaaata caaaagaata tataaacagt gtgtgcgata aggcaattat
    18541 atcatacgag tttgagatag gaagcaaaaa cactagaaga agatacattg tagatagaac
    18601 cattgctaga agcaaaacag gaacaaagac ctctaatgct agattaatag aagtattgaa
    18661 tgacaatatc caaaatgttt tagctgataa agttgtggaa gtaaatgaaa aagtagcaca
    18721 ggttgtagga ttaacggcaa atgattttac taggtcagta gttttaccac aagacaaatt
    18781 taatgagttt ctaagattat cacgtgcaga tagaagagac atgttagaga gaatttttaa
    18841 tcttgagaaa tatggaagaa gtcttggaga aaaagtgaaa aagagaaaaa atatacagtt
    18901 acaaaattta aaagatttga aatcaaaatt aagtcaatat gatggaatta cagaggaagt
    18961 atacaacaat ataaaccaag aattaataga gttaaaaaat ttggaaaaag ataagaataa
    19021 tgctttagac ctagctcaaa aatcttatga agaaagtaaa acagtatatg aagaacaatt
    19081 aaagttagaa aaaaatgaac ttagaaaaaa tgagcttgat ttaaaaaata gtgagataaa
    19141 agaaaagatt gctcttgtag aaaatgatag taacgctaaa aaggtagacc catacataag
    19201 ttcagttcaa aatctagaaa aaaagataga tgaagatagc tttgtagtaa gtaatttaga
    19261 aaagaaatta gcaatattaa atcaggagct tgaagttaca aaaaatagat atgaaaaaat
    19321 aaacaaaatt aagaatgaag aagtccctaa attgagtgaa gaaaaaataa gattgcaaca
    19381 agcaataaaa ttagaagaag agttagtttt attagataga gagttaaaag atctaaaaga
    19441 aagtggaatt aatttaaata agactaaagt tgaattagaa aaagtaaagc aggtgtcaga
    19501 gtccagaaaa gatgcagtta ctaaatctat aaaagaagtt gaaggaaaga ttgataaagt
    19561 aaatataagt gcagaattaa aacaaaaaat atttctagca tatgaatacg agaaagatta
    19621 caacaacgta ttggaagaaa aaaatcaaaa gctaaataaa ctagaagaaa tactcaaaga
    19681 gacagaaaat ataaatttaa aagttagata tattgataaa gataagaatg atgtaaatcg
    19741 taatttagaa aatttatcac ttcacttgga tgttcttctt aaaaaatgtc ctggtaagag
    19801 tgctgattta cttttaaaat ctgaatatgt tactgaatta agaagtaaag caaataatac
    19861 taaagaaaat gaaattaaga aaagcagtat acaagatgaa ttaaagataa tacttgaaag
    19921 taagtttaat actgaaaggg aagtaaattt actaaatgaa aaacttgaaa ataatagaaa
    19981 gaatagagat gacctagaaa aagaattaga agaactaaag tatttaaatt tagcctctga
    20041 acttagacgt gaattaaaag aaaatatgcc ttgtccagtt tgtgggtcaa aacatcatga
    20101 aaatcataat ataactaagt atgatgaaaa tatatctttt gtcaaagaaa aactggagaa
    20161 attagaaaaa gaaaaaataa gtataagaaa caatatagag gaattaaatg ctaaagtaag
    20221 tgggtattta tctatagaaa aaatgaagac taaagaactt gaagatgtaa aaggaaaact
    20281 aggggggatt ccatctagtc aattattaaa aaaacttgat gaagaacaaa gaaaacttgc
    20341 attgttaaaa tctaatattc aggagtggga gaaagaaaaa gagagtactg aaaataaagt
    20401 aacattagct aaagaagaaa aaaataaaat tgaaaaagaa gaattaaaaa taagagagag
    20461 tctgaataat tataagaaat taacaagaga tttaaacata gaaatagaag gtttagaaaa
    20521 taaatgtaaa aaacttaaac aggaatacct aggattaaag acgattacta aagtctctaa
    20581 tctattgtca aaagtaaaag aaataaggga gaatgaaaaa gaattagaat tactaagtac
    20641 tgggcattca aatttattaa aaaatagaga ctcactagat attaaaataa gagaaaatga
    20701 gagtaaacta catgaaatag agatagaatt aataaaggct agagaattat atgtagaaaa
    20761 gaaattgagt agagataata agtataaaga agttattaac ataacgaaag gtgatttagc
    20821 taaaaatctt ttacataatg ttgaagaaaa tatatgtaag atattagaac aagaagaatc
    20881 aagtaagaaa aaattggaag agcaaagatt agaatatgaa aaaaacattg ctgaaaagca
    20941 caatatagat ggtagactta aaactgctaa ggaacaatat aaagaccaaa aatcaacact
    21001 aaataaacta ttagcagaaa ataaatttga aagtatatat gcagtaaaaa gagctttatt
    21061 agatactgat gcagtaaaaa aattgattga agaaatacta gagcatgaag aagaacaaaa
    21121 gttattatca tttaagataa aatcatcaaa agaaaaatta aatggaagaa gcataaagaa
    21181 ggagtacttt gaacagttaa aagatgaaat ttataatttg aaagtagaaa taggaaatat
    21241 atccaaagat attggagcta atcaaaatca gttaataaca ctaaaagact ctttagataa
    21301 gataaatgat tttaataaac aacttaaggt agttgaacac aatgtggact tattggaaga
    21361 attagataaa tgtgtgcaag gaaataaatt tgtagaatat gtttctacaa accaattaaa
    21421 atatatagca ttggaagcat caaaacgatt ggatggaata acaaaaggaa gatatgcact
    21481 tgaaattgac tcaacactaa actttgtaat gagagataac tttaatggag gagaaagaag
    21541 aagcattgat actctatctg gtggagagac attcttgaca tctctatcat tagcacttgc
    21601 tctttcatct caaatacaat taaagggaag tgcaccatta gaatttttct ttttagatga
    21661 aggttttggt tcattagata gtgaactttt agaaattgtt atagaatcct tggaaagatt
    21721 gcatagtaat aatctaagtg tgggtataat aagtcatgtc gaggaactta aaaatagagt
    21781 tcctgttaag ctattagttt catctagtga ggctggaata ggttcaaaag taaaaattga
    21841 atatagttag aaaatatatg gtaattgaat atattatcta atatttccaa ataatatgta
    21901 attgtgatat aataaaaact aatattaaag ttatttataa ttaatattaa tataaaaaca
    21961 tgtaagtagg agtgtggtaa gtgttggaat cgcccaataa tttgattcag attatttttt
    22021 taatagtatt acttataggg tctgcatttt tctcagcatc tgaaacggcc ttaatgtcgt
    22081 tgagtaaaat cagaatcaga tatatgcaag atgaaggagt taaaggagct aagttagtaa
    22141 gttcattaat agaaaatcca aataagcttt taagttctat attggttgga aataacgtcg
    22201 taaatatagc agcaacatcc atatcaacat ctttgtttat aggattaatg ggagaaaaag
    22261 gagtggcact tgctacagct gttatgacag tattagtatt aatatttggt gagattactc
    22321 caaaaacaat agcagcaaat aattcagaaa aggtttctct attagtatct aaacctataa
    22381 aagcaattat atttatatta agaccaatag tatggatatt taatataatt acaaatatta
    22441 tatttaaatt atttggtata acaaataaag gagctaaatc attcataact gaagaagagc
    22501 taaaaactat ggtaaatgta agtcatgaag aaggcgtcct tgaaatggaa gagagagaaa
    22561 tcataaataa tgtttttgaa tttggagata tgcaagctaa aaatgcaatg gtacaaagaa
    22621 tagatatggt agctatagat atggaagata gttatgatga gataatacag gtatttaaaa
    22681 ctgaaaaatt aagtagaatg cctgtgtatg aagaaactat agatgatatt gtaggaatac
    22741 ttaatataaa agatattata tttttatctg atgaagaaat agagtcattt gatattaaaa
    22801 attatatgag agaacctttt ttcacgtatg agttcaaaaa gataacacaa cttcttgaag
    22861 agatgaaact tgaaaaaagt cagatggcta tagttgtaga tgagtatggt ggaacatctg
    22921 gacttttaac tatagaagat ttagtagaag tcattgttgg agatatagag gatgaatatg
    22981 atgaagaaga ggatgaaata caagttataa aagaagatga gtatattgta gatggaagta
    23041 ctaaaattgg tgatgttaat gaacttattg gtgtaaactt ggaatctgag gagtttgatt
    23101 ccataggagg ttttataatt ggacacctaa gcagattgcc agaagaaaat gaagtaattg
    23161 aagttgataa tataagattt tgtatagaaa gtatagaaaa aaatagaatt aaaaaaataa
    23221 gaatatatac ataatgtaat aatgttctta aatttattag aagtgtataa atataaaaga
    23281 tatcttttat atttatacac ttctttttat tttgtattca aataaaacta gtatgaaatg
    23341 gacaaaataa aaatataaat tagaagaaag gagattttta agatgagcat actagaaaat
    23401 aattttttat acaaattaaa aaacaacact atcttttttt gtatatatac attgttattt
    23461 atttttattt acaaagcgtt tccatacata gctccatttt ttctaggtgc tataatagca
    23521 cttatgatta atcctatatc acaaaagtta gaaaataagt ttcgtataaa taaaggtatc
    23581 tctactcttg ttctaagttt tcttgcagtg gctatagtca gtacagttac tacaataata
    23641 gtaataaatt caatgaaaga attaatggga tttttaaata atatatctgc taatcctgag
    23701 gatataagta atactattat gtatttttta aataaaataa atgactttat gaaatcattt
    23761 caagaaatag ccaattttga tgtagaacaa ttagtaaaca aattcagtgg tgaagtaatg
    23821 caaattacaa aaaatcttct tactagtata cttggattgg ctacttctat tccatatatt
    23881 ataatattta taattacctt gtttattgct acctacttta tagcaaaaga ccttgataag
    23941 attgaaaata gtttttataa tatgtttact gttgatgtta gaaagaaggt aaaaaacgta
    24001 aagaaagagg cagggctttc acttgttgga tatataaggg cctatacaat acttatggct
    24061 ataacatttt ttgcaatctg gggaagtttt gctttatttg gattgaaata cggtctaata
    24121 gtagggtttg tagggcttta atggatttaa ttccattcct aggtataata acaatatatc
    24181 ttccagtaat tgtttattat tttcttataa aaaattattt tatagctata agtatgactg
    24241 tgatattttt tgttttgtct ttgattagag aaatacttga acctaaacta gtatcagtaa
    24301 atgttggact aaatccatta gctaccctag cagcgatttt tattggaatc caagtaaaag
    24361 gaataattgg agtaattttt tgtttgggtt tggtatgtat gcatgatata cttaagaagg
    24421 tggatatttt ttaattataa taattgatag atttttttaa aaataaaatt ttattcacag
    24481 gtaaataaaa aaatattaat cttattaaga aagagggtat atacgtgaaa caaaaagtag
    24541 tggaaagatt tttaaaatat gtatcatttg atacaacatc taattctcag tgtgagaact
    24601 gtccatcttc agaaggtcaa agagttttag ctaagtatat agttgaagag ctaaaaacaa
    24661 tgggtgttga tgatgtgagt ttagatgaaa atagttatat aatggctact ttaaaaggaa
    24721 atactgatgg tgtggatact ataggattca tatcacattt agatacaatt gaagatgtta
    24781 gtggaaaaga tattaaacca agaataatag aaaattatga cggaaaagac atagttttaa
    24841 atgaagcgtt aaatgttatt acgtatgtaa aggattctcc agagttggaa gaatttaaag
    24901 gtgacgattt aatagtcact gatggaacaa ctctacttgg ctctgatgat aaagctggta
    24961 tagctgagat agtgactgca atagagtatc taataaatca tccagaaatt aagcatggag
    25021 atataaaaat aggatttaca ccagatgaag aaattggtag aggtgctgat ttatttgatg
    25081 ttgaaaaatt tggagcaaaa tatgcatata ctttagatgg aggaatagtt ggagaacttg
    25141 aatgtgaaaa ttttaatgct gcaaatgcaa ctattactat acatggtaga aatgttcatc
    25201 caggttcagc taaaaataaa atggtaaatg ctatacatat agctgctgaa atatcagaaa
    25261 tgttcccagc agatgaaaga ccagaaacaa cagaaggata tgaaggattt tggcatttaa
    25321 attctatagg tggaaatgtc gagaatgtaa gtatggctta tattattaga gaccattgta
    25381 gagaaaaatt tgaaaataga aaatctatta tgatagagaa tatagaaaaa ataaataaga
    25441 aatacgataa tagagtggaa ttggatttaa aagattctta ttacaatatg aaagaaaaga
    25501 ttgagccagt tatgtttata gttgatatag ctaaagaagc tatggaggaa ttaggtataa
    25561 aaccacgttt agttcctgta agaggtggta ctgatggagc aagattatct tttaatggat
    25621 taccttgtcc aaatatattt actggtggat taaacttcca tgggaaaaat gagtgtatac
    25681 cagttagttc tatggagaaa gctactaaac taattgtaag aatagctgaa aaatatgctg
    25741 aaagagttta gttaaaaagt atttaaaaat taagcattta aagttataat agctatatca
    25801 ttctttataa gtcaagctga ttataagctt gtgttgtatt taaaatggta tagctatttt
    25861 tgtaattatt tttataaaag ataattattt ttagtttagg gtatcaataa aaagtatgga
    25921 tatcaatagg tattaacatt taaaaggggg aattgtattg aaaattaaat ctaaaaaaat
    25981 aatagcattt gcactttcac ttgggattat gttgccaagt tgtgtatatg cagacactat
    26041 tagtaaaaat caaaatgcac aggtagatat gaacaattat cttcaaggta gaaaatctcc
    26101 aaaggaggaa aaacttattg gtgaagatag atttgataca gcgataaaaa tatctcaaag
    26161 tggttggaat aatggttcag aaagggtgtt tctagttaac tcaaattcat tgccagatgc
    26221 attggcttca actcctttgg caagtaaatt ggatgcacca atactgctta caaataaaaa
    26281 tagtatacca tataatgtaa cagaggaaat aaaaaggctt aatccagcag aagttatttt
    26341 aattggaagt gaaggagcta tttcatcaag tgtaaaagaa tctcttgaag atatggaagt
    26401 attagtcagt agaatcggtg gagcagatag agaagaaaca tctttacttc ttactagaca
    26461 gctagatgat actggtgatt taggtgtctc aaaagtggca gtggttaatg ggtataatgg
    26521 actggcagat gcaacttcaa tatcaagccc agctgcaagt gataatacag ctataatata
    26581 tacaggtaag gatagcataa gaagtgaggc aaagaatttt attacacaaa actcaactaa
    26641 gacatacata gtaggtgggg agtacagtat aagtaaaaaa cttgaaggac agttagtaaa
    26701 ctcagaaaga ctagcaggaa cagatagaaa agatactaat gcgaaagttt tagaaaagtt
    26761 ttatggaaaa tcaagtaagg ttaataatat gtattttgca aaagatggaa gtggtagaga
    26821 agctgattta gttgatgggc ttgctgctgg agtattagca tcaaaaacaa agtcacctgt
    26881 agtacttgca agtggaagtt taagtagtgc acagaaaagt tttataaaaa aagtaaaggc
    26941 tgataaattt gtacaagttg gtggaggtaa aaatagtaaa ccatatgcag aagcattagc
    27001 cttacagtaa tattgtgtaa atcaaaatta atatataata atagcaagta aaccaagttg
    27061 aacttcaata tatataataa aataagtaaa ctaagttata tttcagtata atatata
//
LOCUS       DAMJWO010000058        26377 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.059, whole genome shotgun sequence.
ACCESSION   DAMJWO010000058 DAMJWO010000000
VERSION     DAMJWO010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26377
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.059"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     repeat_region   663..1019
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=663..691
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            1258..1446
                     /locus_tag="PC366_002465"
     CDS             1258..1446
                     /locus_tag="PC366_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577968.1"
                     /translation="MKIITDSSRADYFKQRRQNKKTFSVLLDREKVEKIEEHLKKQNK
                     TKTIWLEEKINEELEKEE"
     gene            1565..2431
                     /locus_tag="PC366_002466"
     CDS             1565..2431
                     /locus_tag="PC366_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
                     /protein_id="HDF2577969.1"
                     /translation="MKNLIVKEFNGSQIYTFMWKEKSCWIANQIVGLFDYADVSKTIQ
                     DCIKAEDFEIEQEYDVLKGNEFNDFVTTLNVVANNIISNKARSITIFYEDGLYGFLQY
                     TDKPIGVQFRKWLRREVLPSIRQTGAYITNNANPEKLREKASEIEKLQLAYNSTSMLK
                     ELLDGAGFDNKSKLLTAKTLYKKAGIDLPIEINEEEHYFDTKQIASKLKIYSKSNKPA
                     QLAVCEIIKKIDLEENEVKGVWETNGSWTGTVNKYTKSVIDKVRNWIEENNRPTKIAG
                     EKKNYHVVYKIE"
     gene            3296..3823
                     /locus_tag="PC366_002467"
     CDS             3296..3823
                     /locus_tag="PC366_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HDF2577970.1"
                     /translation="MREGKRRRGCLFWFILIILFSGVVGAIAGNSTNNESTEKQKEDL
                     TKYIGEEGSIGDLKLTVNSISKASEISVASGYLAYTPDSGKYGIINLTIKNQTKESQS
                     FMLNSFTLIGPDDSKYVPSLLIDVGNKYITMDTVNPNLDVTGNIAFEIPKDLLVSDCK
                     LKYSGSEQEFILKEK"
     gene            3961..4728
                     /locus_tag="PC366_002468"
     CDS             3961..4728
                     /locus_tag="PC366_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4428 domain-containing protein"
                     /protein_id="HDF2577971.1"
                     /translation="MGLFGKKKADICCICNTEIGVLNIEDGWICNSCFKEYCDALSMT
                     KAPKILRKLDIEKTISSTKKNNELQKIFNTTNNIENYIEFDEDNKKWLVSKKSINDKK
                     TPIIHSYEDIVKFELLENGETVTKGGIGRALAGGILFGEAGAIVGGITGKKTTRKVVD
                     TFKIKITINNIDNPIEYIELINKKTKTNSSAYEKAYKDAHKILSTLSAITQSIKETDN
                     INTKSVADEILKYKNLLDMEAITQDEFNTKKKELLNL"
     gene            4794..7166
                     /locus_tag="PC366_002469"
     CDS             4794..7166
                     /locus_tag="PC366_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HDF2577972.1"
                     /translation="MATIQTSIKIFDGMTPAFRNMTTSINTTINSLERLQQRLHNPLN
                     TGGIQASQQSLNNIENILTRIEQKIGRNTNEQENFNNKIKQGSEAGSLLVSKLKSLAG
                     IYIGIRGIESITKAADTIASTKARLNLMNDGLQTTEQLNKMIYLSAQSARASYADTAA
                     QVAKLGILAGDAFGSSAEVIKFTELMNKAFVIGGTSANEASAAMYQLTQAMGAGKLQG
                     DEFRSIMENAPLLATKIADAMGKTKDQLKELSSSGAITADVIRNALFKASDEIEKKFA
                     SMPVTFSQALTMMKNDAYMIFGQTLGKISGALQSVRFSEIVVSIRNVMIAISSNIYDT
                     LNIIKNILNSEFFSNLVQGFTFCAVVITKSLGSIVNTALNIVNIFAQNWSIIKPIVFG
                     VASVFILFRGVLLATKIATIGNVIANVAHAASSSLSALMTNIQAAALMRSNGATLSAT
                     IATWGLNAALLACPITWVVLGILAFVVVVFVAVAAVNKFAGTSLTALGVIVGAVFAAV
                     AAIQNVMIWLLNGCIAVNEGITNGWNQCVYLMKQAIAKGVIFIIEKMASLNNSVNNAG
                     NALGKAFIDGANIAIRGVNKLIDLINKIPGINIGKVGEATFTPVKADNSYIKQQIDSL
                     NRWVGDAPEKVKLERMGYKDIGAAFQKGNALGTKWQNAITDKFKDTFDINKMLEDAKK
                     KLGLDDLWNKQNPLNNLGGFGGDLGKNVKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQ
                     ETINRFTGVNIKIDMNNTNNISKDTDVDGIVNVLTEKLNDAMVVSAEGIV"
     gene            7183..7872
                     /locus_tag="PC366_002470"
     CDS             7183..7872
                     /locus_tag="PC366_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDF2577973.1"
                     /translation="MAYDFYLDGVQLPIAPPKLEVKVTNKNKTVDLINTGEVNILKKE
                     GLSEISFEAEFTHNKLPFCRGQFRDVQFFLSKLELLKTDCKPFQFIVSRELGNKVLFN
                     TNIKVSLEEYAISEDADNGSDTKVAIKLKQYRDYSTKKLVLAPPKNETGRPNVKIEPK
                     RVDSVNATNTKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKSMMDKANKGKNLSKY
                     TIYKGQVLKLG"
     gene            7865..9757
                     /locus_tag="PC366_002471"
     CDS             7865..9757
                     /locus_tag="PC366_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2577974.1"
                     /translation="MVDELVLANDRDVRLVIAHWEDFYEPAVIDGITWEIERRGTPSK
                     LEFTIVMDDILEFCEGNSVRLYYKGIGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKILAKDFNLKYNVIEDTKYKISRVEENKTLFDMILTALDDTLRE
                     KKEMYTLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     SGKRDVYIAQDSAHMRSWGILQMFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     ALGDIRVRAGCLVPVFLNLGDIELQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKDEKKNGPAQSIMKKNTGKKVPAIFTAYYPGNNAMEGGKTDCNGKPL
                     DVKSRTVAGPMNREGVKKTWYTDDFLNKHPVFEYGDKVKIILPGTAYDNKVYTVKDNG
                     GRIYVETNGTYHIDILLANASECKKFGRKNGYIIIGGDEEQTYQVEGNNQSNTNNNSK
                     EDKLISIAKSKLGCNYVYGAEGPNNFDCSGFTQWCYKQIGIKIPRTASAQSKAGKAVD
                     LKDRSKWKAGDLLCRIGGGSSNHVVMYIGNNQIIHSPQTGDVVKIESVNSYRKGKAYT
                     HVRRFI"
     gene            9771..10031
                     /locus_tag="PC366_002472"
     CDS             9771..10031
                     /locus_tag="PC366_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HDF2577975.1"
                     /translation="MSQDLLQIIKKAAMDAVETSNPMRVVFGTIESISPLRVKIEQKL
                     SIGEIFLIQTDTFKRYTDKKMGDKLVLIRMQGGQQYLILDRM"
     gene            10036..10455
                     /locus_tag="PC366_002473"
     CDS             10036..10455
                     /locus_tag="PC366_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HDF2577976.1"
                     /translation="MLPSDNLDYDIEDVSIINFDVRQEPSKTFKLHIEKSKIDGICDD
                     VEALKQTIFLILNTERYEHLIYSRNYGVELNDLIGEPISYVIPELERRITEALIQDDR
                     IENIDNFEFQNIKGKVQCRFSVHTKYGNIKAEKVVSV"
     gene            10456..11505
                     /locus_tag="PC366_002474"
     CDS             10456..11505
                     /locus_tag="PC366_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDF2577977.1"
                     /translation="MFELMTFENIIKRMLDSVPDTFDKREGSIIYNALAPVAIELTET
                     YIAMDELLDQTFVDTASYYYLEKRCKERGITPLEATHTIAKGVFNIDIPLDSRFNLGE
                     YNYVAIERISEKTYKMKCETTGPVFELGKLIPIEYIDGLETAELTEILINGEDEESED
                     SLRQRYYDSLNSQSFGGNIQNYRDEVNKIQDVGGVKVYPTWDGGGTVKLVIINSNFKV
                     PSEELVNLVQEEIDPIGHQGEGLGLAPIGHRVTVEGVTSTTINISAEITYKNGYTWEN
                     IKSIAEEAIDDYLNELNMSWEDEENLIVRISQIETRLLSIDGVLDIANTMINDVKSNL
                     TIDSNSIVVRGEVVG"
     gene            11498..12115
                     /locus_tag="PC366_002475"
     CDS             11498..12115
                     /locus_tag="PC366_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HDF2577978.1"
                     /translation="MDKEINLINYLPQILQDKEEYIKVFNVENKEIKTLHDKLKDLSN
                     DQFLEDLTISGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDNV
                     VGEGNYELTINNATYNIHLESDARNQDWFEEVHSFVSNIKPCNMTLDYTRVLISKDNY
                     MNFGITTLMGQEITIYPWSPPDIETYGEIDVLTGNGVGYQEITIF"
     gene            12127..13152
                     /locus_tag="PC366_002476"
     CDS             12127..13152
                     /locus_tag="PC366_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDF2577979.1"
                     /translation="MAIDKSYYTIITDVGKAKIANASVTGNKVGFVKIQLGDGGGSEY
                     TPTESQTELKNVVWEGNIGNTTTDETAPNCIILESLIPSSVGGFMIREIGYLDDENNL
                     IAISKYKECYKPSIEQGAVVDMKVKTVLIVSNINNIELKIDPTIIFATLKDIQDLDAK
                     ISNVNTKIDTTKTELTSNIETAKTELNTRIDTENEKQNIKIDQLIAGGSNVASTQTIT
                     IDDWIDNQEGGFKATVTHGLLTQRITVSIIDATTKDNVVPDFTIIDDNSIEVRSGVKV
                     ELNVYVINGNAETHFINATVDDNRVSEMTTYSSKKIHEEIGKVAEQLTGINSNIISTV
                     NNDILPI"
     gene            13169..14695
                     /locus_tag="PC366_002477"
     CDS             13169..14695
                     /locus_tag="PC366_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577980.1"
                     /translation="MALSMSYFNLPDKRKYTKNLAFNPFAGGRQNFEWTGGDHGLNGE
                     FKETCLSCTYNGSTLNWGSGNVWVLGEYGQYTFTYNCESMHVDTQQKFPYTSNRIITI
                     KGRPVISGSDTSLGNKRKGFSVDFTVSDDTPNVNLIVRAYLDDKLIQNITPVVQNSTL
                     TATVTDSQLNSLSVDGNHKLKIQLNDGYDNFDRIFTFKKIEKGIDISTSLVTDSQAKF
                     TVTKIYSELTKIECYLDETLKETFTTDLYSEKTINYELIDNAIHTLKIVVTDAENVVE
                     EKVISISKNIMPLQPDATLQDISTKLTEIGQGVRNGKTSIINTLALKNIDASLNNTLV
                     ELSEKIKGGFDSGDASLQDLMNQLTQANNTISQLNTKYKVASGTVTSFADSTKIAYPY
                     LTDNVTKPGSWIKVSNLGFKPNIFFADFDYYDAEYKNNYKLFLFACNGVATQRGVDFS
                     SVTSFIRKSGDEYFHANGWLYSNSEGDVYFNNTGVQIPAYNFDSTQKHTYKWYAIKFI
                     "
     gene            14710..15003
                     /locus_tag="PC366_002478"
     CDS             14710..15003
                     /locus_tag="PC366_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577981.1"
                     /translation="MNVPNRIIYDQTGRTIFETGESCGDVLPHYTITELHYIDIEYGS
                     IDYTRNRVIGINIETKEPILEEIPVYITDEEKRIQELENQLLIAENEKVGGLL"
     gene            15003..15185
                     /locus_tag="PC366_002479"
     CDS             15003..15185
                     /locus_tag="PC366_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577982.1"
                     /translation="MNINNVVVRILAERILSKGLNPLKNREFQLDDVTNTEYRKAVED
                     YIIKNSGVVEGAEPTI"
     gene            15219..15785
                     /locus_tag="PC366_002480"
     CDS             15219..15785
                     /locus_tag="PC366_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577983.1"
                     /translation="MTFKELVNKVRNLVLEAKNVTIEDTESKFTSENVEGALKECIDR
                     ADEAFQEADSGKTLLSTAIGSPTTSEQTFQDYANYITGFKSNISNLETQLKSKYSIRY
                     GPIDGYDGNPFSANFGKSASYLIVYVYFRRSVYYYNPSGSSLGSNTGGSERAWITINS
                     NKTGFSVHSYDTSYESYPFTGYYIACFA"
     gene            15816..16106
                     /locus_tag="PC366_002481"
     CDS             15816..16106
                     /locus_tag="PC366_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2577984.1"
                     /translation="MEEISINLLCAVAGVVISYLAFRNNSNRKIQDETETTTKLEQQI
                     TFLCENVRDIKHDVAKFNTSFLDISERVAKIEASTKQAHLRIDEIVNRIGGK"
     gene            16110..16367
                     /locus_tag="PC366_002482"
     CDS             16110..16367
                     /locus_tag="PC366_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDF2577985.1"
                     /translation="MDNLISFIPEQLLILVAALSIIGKGCKKYKQLDNKYIPVVLLIL
                     GIGFSIWMLGLNPVAVLQGVICWGVAIGINQTYKQLKDGEK"
     gene            16628..17491
                     /locus_tag="PC366_002483"
     CDS             16628..17491
                     /locus_tag="PC366_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HDF2577986.1"
                     /translation="MVEVKEEKTFDEQIDILKSRGLIINDKEDAKFVLSNVNYYRFTA
                     YLLSFKNDDGSYKEGTTFEEVYDIYRFNKEFRILLTDLLGSIEIAFRTYIAYTLAIKH
                     GACGYLERESFKDEKFYINFLTALEREKSNNSDKLFIIHHKEKYEGKLPIWVATEIMT
                     FGMLSKLYSNMLPEDTRYIKNNLCRVNTLLVKSWLQSLTQVRNQCAHYGRIYNNNFRI
                     ITIKNEYKKYNLDNKKIFSYILAMKHLTMDKLIWNSFFIKLQKLINDYNNSIDLKLIG
                     FPNNWIEILAK"
     gene            17570..18382
                     /locus_tag="PC366_002484"
     CDS             17570..18382
                     /locus_tag="PC366_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2577987.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADTFRKE
                     GHKADVIICPEKQFKTKAEEKTYKIPRVNSGGYDLLIELHLNASDGQGKGSEVLYYSN
                     KGLEYATRICNKLGTVFRNRRAKLDKGLYILNSSNPTAVLIESFFCDNKEDYEKAKKL
                     GHEGIAKLIVEGVLNKNINNEGVKQMYKHTIVYDGEVDKISATVVGWGYNDGKILICD
                     IKDYVPGQTQNLYVIGGAACEKIGSMTKEKFTMIKGNDRFDTLYKALDFINR"
     gene            18476..20875
                     /locus_tag="PC366_002485"
     CDS             18476..20875
                     /locus_tag="PC366_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF2577988.1"
                     /translation="MIFKKYIKSLLIVVSVTLIMNKSILFVNALDLESNNNIKSYKRK
                     NVKEIDISNKFVDESFRRDIVEKVLDNRDDPLTNEVASKDNYKIYESDLNKIESCLEL
                     DLHKNPDVSNPNKIDNLDGIENFRNLEKLDCSSNNLESVDLSKNIKLKYLDISGNKIL
                     NIDLKNNNLINELHCDANKLSNLDLKNNKNLVSLFFTSNELTEIDLSNNVNLENLQFL
                     NNNLKSIDLSHNKKLKSLNCTNNKLKSLDLSNNVFLKNLSCSGNNLSKLNIKGLTSLE
                     YLGCAKNKLQDLDVSTNIKLDSLLCGKNSLTKIDISKNKELNSLECSGQYIEKSIIKN
                     GENIVVDIGIENSKLKELYPQNYNISTGFLTWENLSDFPNSISYSLEYEYGPVNDTET
                     MDVNISIDKLVKCRIRYIDYDGSIINEKEISDNSSINEIQINPQRENYEFSGWRNNKD
                     EKIYTSEQVSKLVFDDSTDFIATYKRKSTGSSGSSGGTSSKEDFNIAPSKEKITGADR
                     NETSVKISQKGWNKADNIVLINDSSISDALSATPFAKSKDAPILLTKNNNLNKLTEKE
                     INRLEAKNVYIVGGLKSVDEKVVSDLKKKGLNVIRISGNDRYETSIKLAKELDKNSNL
                     SKVVVVNGEKGLADAVSMGAISAKEEMPILLTNQNDDMKDIKDLIANKNISKSYVIGG
                     ESLFNNKEVNNTLPSVTKIAGSDRTETNSKVISHFYSKDTLNDLYVAKNGMNKQDDLV
                     DALSVGVLAGKTESPVVLVGNGLDDSQKELIKNKKFKNITQIGGNGNEKAFNEVENLV
                     K"
     gene            complement(20916..21101)
                     /locus_tag="PC366_002486"
     CDS             complement(20916..21101)
                     /locus_tag="PC366_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HDF2577989.1"
                     /translation="MILLEQRKLRIGFNKSGKGSFTPRLILPMSWIKEMNISPDERDV
                     LVTFEDGKIIIEKTENE"
     gene            21796..22473
                     /locus_tag="PC366_002487"
     CDS             21796..22473
                     /locus_tag="PC366_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF2577990.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNAVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSRLYFDLSTPGPNHNTKIDINPPS
                     FEKPLKK"
     gene            22647..24683
                     /locus_tag="PC366_002488"
     CDS             22647..24683
                     /locus_tag="PC366_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HDF2577991.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLKNVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGTFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKV
                     FEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQ
                     LKLYVDNVKSSPTGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISENFIPNAT
                     FLAKKYNEENTIIGFLNNYRLKDDKTSYYVCQSNSCSQPINDLQKLKDMILGVE"
     gene            complement(24874..25440)
                     /locus_tag="PC366_002489"
     CDS             complement(24874..25440)
                     /locus_tag="PC366_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2577992.1"
                     /translation="MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYM
                     TILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKV
                     TDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANF
                     MEYEEIDKIKSEALEEFAKRRNRVNKND"
     gene            25724..26251
                     /locus_tag="PC366_002490"
                     /pseudo
     CDS             25724..26251
                     /locus_tag="PC366_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
BASE COUNT        10655 a         2872 c         4632 g         8218 t
ORIGIN      
        1 tagaaaaaat attgtttata taaaataaaa aataaaaatt tttattaaaa aaatgaaaac
       61 ttgattataa agcaattaat ttataaaata tatataaata agtaggtatt tatttacttg
      121 aatttcattg tttatataaa aaaaatggaa aaatatgtaa taattatagg ttataataat
      181 tgtagcaagg ataataatcg aaagtgcgaa gggtgattat tttcatatta aacgccaaat
      241 tccaaataag gaaggaggtg aaattatatg ataggttttt tattaagcat actagctggt
      301 gttatatcag cttatattta tgacaaaata aaaaatcacc cagacgccaa taagggtgat
      361 ttaaaaaaat aatattttca cttaacaact gaaaataatc actctttgta ggaataaatt
      421 atttccttgc ttttattata ccacaaattg gtacagatat tcaaaaataa tatttttatg
      481 atataataaa aatgtagaga ttttgcagtg agcgatattt gtgataaatt gaagtttaac
      541 agttgcaata taaggcgttg agggtgtgtg ataaatgtta tcaattgcac tactcatggt
      601 tcactgcaaa tttaagagag ttgtatatgt gtaggtattg aaaatactca acttattttg
      661 gggttttaga ttaactatat ggaatgtaaa tgttgtaaga agtatcattc tattttttaa
      721 tctttctgtt ttagattaac tatatggaat gtaaatttca gtgagaataa gctttattgt
      781 cgatgtaaca ctcgttttag attaactata tggaatgtaa atagtacata taatgagtct
      841 ttaacatcag ttatgaaagg ttttagatta actatatgga atgtaaatga ttgtacttta
      901 gcgtctgcac tagctttgtc tatcgtttta gattaactat atggaatgta aattatttta
      961 cagatgaaca attacagtta cttcttgaat gttttatatt aactatgtgg attcaaaatt
     1021 aaatagaaaa aagaaagcac ttacttaaat agtaggtgct tttgttttgc tcaaattact
     1081 taattataaa gttgctaagt acaacttttt agaattatac aatataaaaa tgcactaaag
     1141 tgattgattt tgctcaagtt ggtcggttga gtaaaataat tagaaaaaaa tgttaaaaaa
     1201 ctcttgaaaa gtgtcgcgat acaatgtata attatattat cgcgatacag aaaagaggtg
     1261 aaaattatta ctgatagcag tagagcagat tacttcaagc agagacgaca gaataaaaaa
     1321 acttttagtg ttctactaga tagagagaaa gtagagaaaa ttgaagaaca tttaaaaaag
     1381 cagaacaaga ctaaaactat ttggcttgaa gaaaagatta atgaagagct agaaaaagag
     1441 gaataaaaaa taagagacgt tctccccgac caaagattga acatccctta ttgacgtata
     1501 ttatatacac taactatagt atacgtcatt ccttgaaaaa attcaattaa ggagtgtaat
     1561 agttatgaaa aatttaatag taaaagagtt caatggaagt caaatttata cttttatgtg
     1621 gaaagaaaaa tcttgttgga tagctaatca aatagttgga ttattcgatt atgctgatgt
     1681 atctaaaaca atacaggatt gcataaaagc agaagacttt gagattgaac aagagtatga
     1741 tgtattgaaa ggaaatgaat ttaatgattt tgtaactact ttaaatgtag tcgcaaataa
     1801 tataattagt aataaagcta gaagtataac tattttttat gaagatggtt tatatggatt
     1861 tttacaatac acagacaaac ctattggtgt acagtttagg aaatggctta gacgagaagt
     1921 tttaccaagc ataagacaaa ctggtgcata cataactaac aatgctaatc ccgaaaaact
     1981 aagagaaaaa gcaagtgaga ttgagaaatt acagttagct tacaatagta catctatgtt
     2041 aaaagaacta ttagatggtg caggctttga caataaatcc aaactattaa cagctaaaac
     2101 attatataag aaagcaggaa ttgatttacc aatagagata aacgaagaag aacattattt
     2161 tgatacaaag caaatagcat ctaaactgaa aatatattct aagagtaata aaccagcaca
     2221 gttggctgtt tgtgaaatta ttaaaaagat tgatttagaa gaaaacgaag tcaaaggcgt
     2281 ttgggaaact aatggttctt ggactggtac tgtaaataaa tatacaaaga gtgtaataga
     2341 taaggttaga aattggatag aggaaaataa tagacctact aagattgcag gtgaaaagaa
     2401 gaattatcat gtggtttata agattgagta aatttataag attgtattaa ataatttagt
     2461 ttagttttgg ggggattaat acaatgcatg agaatttact tgatagtata gatattgaaa
     2521 agagaaaaga agaatttaga attaaacttt tgaaaataag agaaacagat atagatatat
     2581 ataataagat agaaagtata gtatataaac tttcttagaa aaaattagag aaaaataatt
     2641 aaataaatag ataaagcact tggatatttc actgtttcaa gtgctttata tggtaaaaaa
     2701 tggtataata aaatatagga attttgcagt gttcgatttt tctactcaag tatagtttaa
     2761 caattggaat acaaggcatt gagaaggttt gataagtgtt atcaattgca ctattacccg
     2821 ctcactgcaa atttgagaaa gttatatgtg tgtaagtctt ggaaatacac aatttatttt
     2881 ggggttttat attaactata tggaatgtaa atctttgtaa tggtagtgta tttaagattg
     2941 aaacatcaag ttttatatta actatatgga atgtaaatca acattagtag ttgtctttat
     3001 acacatagca tcacgtttta tattaactat atggaatgta aatacagctc ccaagacata
     3061 caacgaatct gtaacatcag tgttttatat taactatgtg gtatgtaaaa gacttattta
     3121 cagctttatt tgctaaatca gaaggtttta tattaactat gtggacttaa aattaaaaat
     3181 aattaaaaaa cacttactaa tgtaggtgtt tttttattga aaggaagtga ttataatgta
     3241 aaaattttga agatatagta taatattctt ataaaatata atttaggggg atattatgag
     3301 agaaggaaag agaagaagag gatgtctatt ttggtttatt cttattattt tattttctgg
     3361 agttgttgga gcaatagcag ggaacagtac taataatgaa agcactgaaa aacagaaaga
     3421 ggatttaact aaatatattg gtgaagaagg tagtatagga gatttaaaat taactgttaa
     3481 tagcatttca aaagctagtg aaatatcagt agcatctggt tatttagcat acactccaga
     3541 tagtggcaaa tatggtatta taaatttaac aataaaaaat caaactaagg aaagccaatc
     3601 ttttatgcta aattcattca cattaatagg accagatgat tcaaaatatg ttccatcttt
     3661 attgattgat gtaggaaata aatatataac tatggatact gtaaatccta atttagatgt
     3721 aacaggtaat attgcatttg aaattcctaa ggatttacta gtttctgatt gtaaactaaa
     3781 atatagtggt tcagagcaag aatttatatt aaaagaaaaa taatatatag atttaaaaat
     3841 atgaagcatt tactttaaat aagtaagtgc ttttttaatt aaaaggaggt gataataatg
     3901 taaaaatttt acttatatag tataattaca ttataaaatt attgtactgg ggggaatctt
     3961 atggggttat ttggaaagaa aaaagcagat atatgttgta tttgtaatac tgagatagga
     4021 gtactgaata ttgaagatgg ttggatatgc aattcttgtt ttaaagaata ttgtgatgca
     4081 ctttctatga ctaaagcacc taaaatttta agaaaattag atattgaaaa gactatatca
     4141 tcaactaaaa aaaataatga acttcaaaaa atatttaata caactaataa tatagaaaac
     4201 tatatagaat ttgatgaaga taataaaaaa tggcttgtgt ctaaaaaaag tataaacgat
     4261 aaaaaaactc ctatcattca ttcttatgaa gatatcgtga aatttgaact tcttgaaaat
     4321 ggtgaaactg taactaaagg aggaatagga agagctttag cgggaggaat tttatttgga
     4381 gaagcaggag ctatagttgg agggataaca ggtaaaaaaa caacaagaaa agttgttgat
     4441 acatttaaaa ttaaaataac aattaataat attgataatc ctattgagta tatcgaatta
     4501 attaataaaa aaacaaaaac taattctagt gcttatgaga aagcttacaa agatgcccat
     4561 aaaattttat caacattatc tgctattaca caaagcatta aagagacaga caatataaat
     4621 actaaatctg tagcagatga gatattaaaa tataagaatc ttttggatat ggaagctatt
     4681 acacaagatg aatttaatac taagaaaaaa gaattattga atttgtaata taataaacac
     4741 ttactaatgt aggtgttttt ttatatggaa atttatgaaa ggagagtgag aaagtggcaa
     4801 cgatacaaac ttcaataaag attttcgacg gaatgacacc tgcttttagg aatatgacta
     4861 catctattaa tacgacaatt aatagccttg aaaggttaca acaaagattg cataatccgc
     4921 ttaacacagg tgggatacaa gcatctcaac aaagtttaaa caatattgaa aacatattaa
     4981 ccaggataga acagaaaatt ggaagaaata caaatgaaca agaaaacttt aataataaga
     5041 taaagcaagg aagtgaagca ggttctctat tagtatctaa actcaaaagt ttggctggca
     5101 tatatattgg aataagaggt atagaaagta ttacaaaagc agcagataca attgcaagta
     5161 caaaagcacg tttaaattta atgaatgatg gattacagac aacagaacaa cttaataaga
     5221 tgatttattt atctgctcaa agtgcaagag ctagttatgc agatacggca gcacaagtcg
     5281 ctaaacttgg aatattagca ggagatgctt ttggaagttc ggcagaggtg ataaagttta
     5341 cagaacttat gaataaagct tttgtaattg gaggaacatc agcaaatgaa gctagtgcgg
     5401 ctatgtatca gcttactcaa gctatgggtg cagggaaact tcaaggtgat gaatttcgct
     5461 ctataatgga aaatgcacct ttattagcca ctaaaatagc tgatgcaatg ggaaaaacta
     5521 aagaccaatt aaaggaattg tcaagtagtg gagcaataac agcagatgtt ataagaaatg
     5581 cactatttaa agcttctgat gagatagaaa agaaattcgc aagtatgcca gtcactttta
     5641 gtcaagcact tactatgatg aaaaatgacg cctacatgat ttttgggcaa accctcggaa
     5701 agataagtgg agcattgcaa agcgttagat ttagtgaaat tgttgtatct ataagaaatg
     5761 ttatgattgc aatatcttca aacatttacg atacattaaa tattataaaa aatattttaa
     5821 atagtgaatt cttttcaaac ttagtgcaag gatttacatt ttgtgcggta gtaataacta
     5881 aaagcttagg ttctattgta aatactgcat taaatatagt taatatattt gcacaaaatt
     5941 ggagtataat aaaacctatt gtatttggtg tagcttctgt ttttatattg tttagagggg
     6001 ttttgctagc gactaaaata gctacaatag gtaacgtaat tgcgaatgtt gctcacgctg
     6061 cttcctcttc actatcagca cttatgacta atatacaagc agcagcactg atgcgttcga
     6121 atggagctac tttatcagca acaatagcca cttggggttt aaatgcagct ttattagctt
     6181 gtccaatcac atgggtagta ttaggtattc tagcatttgt agtagtagtt tttgttgcag
     6241 tagcagcagt aaacaaattc gcaggtacaa gtttaactgc cttaggagta attgtgggtg
     6301 ctgtatttgc agcagtggca gcaatacaaa atgttatgat ttggttatta aatggctgta
     6361 tagctgtaaa tgaaggcatt acaaatggtt ggaatcaatg tgtatatcta atgaaacaag
     6421 ctattgcaaa aggtgtaatc tttataatcg agaaaatggc atctctaaat aattctgtaa
     6481 ataatgctgg aaatgcactt gggaaagctt tcatagatgg ggcaaatatc gcaatacgag
     6541 gtgtaaacaa attaattgac ctaataaata aaataccagg gataaatatt ggtaaagtag
     6601 gagaggcaac gtttacgcca gttaaggcag ataatagtta catcaaacaa cagattgata
     6661 gcttaaacag atgggtagga gacgcaccag agaaagtaaa attggagcga atgggataca
     6721 aagatattgg agcagcattt caaaaaggaa atgcacttgg aactaaatgg caaaatgcta
     6781 taactgataa atttaaagat acttttgaca ttaataagat gctagaagat gcaaagaaaa
     6841 aattaggatt agacgatttg tggaataaac aaaatccttt aaacaacctt ggtggatttg
     6901 gtggagattt aggaaaaaat gtaaaggaca cggcaggcaa tactgcaaag atggcaaaga
     6961 ctatggataa aagtcaagag gacttaaaat acttaagaga tatagcagag caagaaacaa
     7021 tcaatcgatt cacaggagta aacattaaaa tagatatgaa caatacaaac aacataagta
     7081 aagatacaga tgttgatgga atagttaatg tcttaactga aaaactgaac gatgctatgg
     7141 ttgtatcagc ggaaggaata gtttaggaag gagagtgaga aaatggctta tgatttttac
     7201 ctagatggag tacaactacc aatcgcacca cccaagcttg aagtcaaagt gacaaacaag
     7261 aacaagacag ttgatttgat aaatactgga gaagtaaaca tattaaaaaa agaaggatta
     7321 tctgaaataa gttttgaagc agaatttaca cataataaac tacctttttg tagaggtcaa
     7381 tttagagatg ttcaattctt tttaagtaag ctagaattac taaaaactga ttgtaagcca
     7441 tttcaattta ttgtatctcg tgagttaggt aacaaggtct tatttaacac taatataaaa
     7501 gtatctcttg aagagtatgc tatttcagaa gatgcagata atggctcaga tacaaaagtt
     7561 gcaataaaat taaagcaata tagagattac tcaactaaaa agttagttct tgcccctcct
     7621 aaaaatgaga ctggtagacc taatgtaaag atagagccaa aacgagttga ttcagtcaat
     7681 gccacaaaca ctaaaacata tacagtaaaa gcaggggata gcctttggtc aatttgtcag
     7741 aaacaacttg gtaatggttc attatataag aaagtatacg aactaaataa atctatgatg
     7801 gataaggcaa ataagggcaa aaacttaagt aaatacacta tttataaagg gcaggtgtta
     7861 aaacttggtt gatgaattag tgttagcaaa tgatagagat gtaagattag taatagctca
     7921 ttgggaagat ttctacgaac ctgctgtcat tgatggtatc acatgggaga tagaaagacg
     7981 aggtacacct tctaagttag agtttacaat agtcatggat gatatactag agttttgcga
     8041 aggaaattct gtaaggctgt attataaagg aataggcata ttttatggat atatatttca
     8101 aaagaaaaga gataaagaaa atcacattaa aattgttgct tacgaccagt tgagatattt
     8161 taagaataaa gatacttatg tatatagtaa taaaactgca agtgaacttg taaaaatctt
     8221 ggctaaagat tttaatttaa aatacaatgt catagaagat actaagtata aaatatctag
     8281 agtcgaagaa aataaaacac tctttgacat gatactaaca gcactagatg atactttaag
     8341 agagaaaaaa gaaatgtata ccttgtatga tgattttgga agaataacat taaagaatgt
     8401 tgcatcaatg aaactagata ctgtcatgaa caatgatgta attgaggatt ttgactataa
     8461 ttcatcaata gatagtgata cttacacaaa gattaaactt gtaagagaca acgaggagtc
     8521 aggaaaaagg gatgtatata ttgctcaaga ctcagctcac atgagaagtt ggggaatact
     8581 tcaaatgttt gatacagtag acaaaaacat gagtgaagca gagataaaac aaaagtgtga
     8641 tatacttcta aaactatata ataagaaaac taagtcatta agtttaaaaa atgcacttgg
     8701 agatattaga gtgagagcag gttgtttagt acctgttttt ttaaatctag gagatattga
     8761 attgcaaaat tatatgttag ttgagaaagt aaaacataca tttgaaaata attcacattt
     8821 catggatttg accttggttg atggagacga atttgcttca tattcttcaa gctcatatag
     8881 tagtggaaat actaataata aagatgaaaa gaaaaatggt cctgcacaaa gtattatgaa
     8941 aaaaaataca ggtaaaaaag ttcctgctat atttactgca tattatccag gaaacaatgc
     9001 aatggaaggt ggaaaaacag attgcaatgg aaagccactt gatgtaaaat caagaactgt
     9061 tgctggtcca atgaatcgag aaggagttaa gaaaacttgg tatactgatg attttctaaa
     9121 taaacatcca gtttttgaat atggagataa agtaaaaatt atacttcctg gtactgccta
     9181 tgacaacaaa gtatatacag ttaaagataa tggaggaaga atatatgttg aaacaaacgg
     9241 aacatatcat atagatatac tattagctaa tgctagtgaa tgtaaaaaat ttggtagaaa
     9301 gaatggctat ataattatag gtggagatga agaacaaaca tatcaagttg aaggtaataa
     9361 ccaaagtaat acaaataaca attctaaaga agataaatta attagtatag caaaaagtaa
     9421 actgggttgt aattatgtgt atggagcaga aggtcctaat aattttgatt gcagtgggtt
     9481 tactcaatgg tgttataaac aaataggtat aaaaattcct cgtactgctt ctgcacaaag
     9541 taaagcagga aaagcagtag atttaaaaga tagaagcaag tggaaagcag gagacttatt
     9601 atgtagaatt ggtggaggaa gtagtaatca tgttgtaatg tacattggaa acaatcaaat
     9661 aattcattca ccacaaacag gagatgtggt aaaaatagag tctgttaatt cttatagaaa
     9721 aggaaaagca tacacacatg tgagaagatt tatataagtg aggtggcaat atgagccaag
     9781 atttattaca gataataaaa aaagctgcaa tggatgcagt agaaacaagc aacccaatga
     9841 gggttgtatt tggaacaata gaaagtatta gtcctctaag agttaagata gaacaaaaac
     9901 tatctattgg tgaaattttt ctaatacaaa cagatacatt taaaagatat acagataaaa
     9961 aaatgggaga taaattagtc ttaattcgta tgcaaggagg gcaacaatac ttgattttag
    10021 ataggatgtg ataaagtgtt accaagtgat aatttagatt atgatattga agatgtatca
    10081 ataattaatt ttgatgtaag acaagagcca agtaagacat ttaaacttca tatagaaaag
    10141 tctaagattg atggtatttg tgatgatgta gaagcattaa aacaaaccat ttttttaatt
    10201 ttaaatactg aaaggtatga gcatcttatt tattctagaa attatggtgt tgaattaaat
    10261 gatttaattg gagaacctat ttcatatgta atacccgaac ttgaaagaag gataacagaa
    10321 gcactaattc aagatgatag gattgaaaat atagataatt ttgagtttca aaatataaag
    10381 ggtaaagtac aatgtagatt ttcagttcat acaaaatatg gaaatataaa agcagagaag
    10441 gtggtgagtg tataattgtt tgagttaatg acatttgaaa atataattaa aagaatgtta
    10501 gatagtgtac cagatacttt tgataaaagg gaaggttcta taatatataa tgctcttgct
    10561 cctgttgcta tagaacttac agaaacatac attgctatgg atgaattact agaccaaaca
    10621 ttcgtagata ctgctagtta ttattattta gagaagagat gtaaagaaag gggaataaca
    10681 ccacttgaag ccactcatac gattgctaaa ggagttttta acatagatat tccacttgat
    10741 tctaggttta atctaggaga atataactat gtagcaattg agagaatatc tgaaaaaaca
    10801 tataaaatga aatgtgaaac tactggacct gtatttgagt taggaaaact aatacctatt
    10861 gaatatatag atggtcttga aactgctgaa ctaactgaaa tcttgataaa tggagaggat
    10921 gaagagtcag aagatagttt aagacaaaga tattatgata gcctaaattc acagagtttt
    10981 ggcgggaata tacaaaacta tagggatgaa gttaacaaaa tacaagatgt tggaggagtt
    11041 aaagtttatc caacttggga tggaggtggg actgttaagt tagtaataat taactctaat
    11101 tttaaagtgc caagtgaaga attagtaaac ttagttcaag aagaaattga cccaattgga
    11161 caccaaggag aaggcttagg attagcaccg attggacacc gagtcacagt tgaaggagtt
    11221 acaagtacaa ctataaacat atcagcagaa ataacataca aaaatggcta cacttgggag
    11281 aatataaaat caattgcaga agaagcaata gacgactatt taaatgaact taacatgagt
    11341 tgggaagatg aagaaaactt aatagtccgt atatctcaaa ttgaaactag attacttagt
    11401 attgatggag tattagacat tgcaaataca atgataaatg atgttaaatc taatctaaca
    11461 atagatagta acagcatagt agtgagaggt gaggtagttg gataaagaga ttaatctaat
    11521 aaattacttg ccacaaattc tacaagataa agaagaatat ataaaagtat ttaatgtaga
    11581 aaataaagaa ataaaaacac tacatgataa attaaaggac ctatcaaatg accagttttt
    11641 agaggaccta actataagtg gtataaaaag atgggaaaag ataatgtcta taactcctaa
    11701 aagtaatgag agtttagaag atagaaggtt taggattttt agtaaatata taagtaaatt
    11761 accttactca gagagatttt taaggaactg gctagataat gtagttggag aaggcaatta
    11821 tgaattaact attaataatg ctacttataa catacacctt gagagtgatg ctagaaatca
    11881 agattggttt gaggaagttc attcttttgt aagtaatatt aagccatgta atatgacttt
    11941 agattacact agagtgctta taagcaaaga caattatatg aattttggta taacaaccct
    12001 aatgggtcaa gaaataacta tatacccttg gagtccacca gatatagaaa cttatggaga
    12061 aattgatgta ttaactggca atggagttgg ataccaagag ataacaatat tttaggaggt
    12121 gatatattgg ctatagataa aagttattac actataatta cagatgtagg aaaagcaaag
    12181 atagcaaatg caagtgtcac aggtaataaa gtagggtttg taaaaattca acttggtgat
    12241 ggtggaggaa gtgagtatac tcctactgaa agtcagacag aacttaaaaa tgtggtatgg
    12301 gaaggcaaca tcggaaatac aaccacagat gaaactgcgc caaactgcat aatattagag
    12361 agtttaatac catcaagtgt aggtggattt atgataagag aaataggata tttagatgat
    12421 gaaaataatc taattgcaat ctctaaatat aaagaatgtt ataaaccttc tatagaacaa
    12481 ggagcagttg ttgatatgaa ggttaaaact gtgcttattg tatctaatat aaataatata
    12541 gaacttaaaa ttgaccctac aataattttt gctacgctca aagatataca ggatttagat
    12601 gctaaaataa gcaatgtaaa cactaaaatt gatacaacta aaacagagtt aacaagcaac
    12661 atagaaactg ctaagacaga gttaaacact agaattgaca cagaaaatga gaaacaaaat
    12721 attaaaattg accagctaat agcaggtggt tcaaatgttg catctactca aacaataaca
    12781 attgatgatt ggatagataa tcaagaaggt ggattcaaag caactgtaac acatggttta
    12841 ttaacacaga gaataactgt aagtattata gatgctacta caaaagataa tgtagtaccc
    12901 gatttcacaa ttatagacga taattctatt gaggttagaa gtggagtaaa agttgagtta
    12961 aatgtttatg tgattaatgg gaatgcagag actcatttta ttaatgcgac tgtagatgat
    13021 aatagagtgt ctgaaatgac tacttattca tcaaaaaaga tacatgaaga aattggtaag
    13081 gtagcagagc aactgacagg aattaatagt aatattatat cgactgtaaa taacgacata
    13141 ctacctatat agaaaggagc gtgaaaaaat ggcgttatca atgagttatt ttaatttacc
    13201 tgacaaaaga aaatatacta aaaatcttgc atttaatcca tttgcaggtg gaaggcaaaa
    13261 ttttgagtgg actggtggtg accatggact aaatggtgag tttaaagaaa cttgcttaag
    13321 ttgcacttac aatggttcaa cattaaattg gggttcagga aatgtttggg tcttggggga
    13381 atatggtcaa tatacattta cttataattg tgaatcaatg catgtggata cacaacaaaa
    13441 atttccgtat acttctaata gaataataac tataaaaggt agacctgtaa tatctggttc
    13501 agatacttca cttgggaata aaagaaaagg atttagtgta gattttactg taagtgatga
    13561 tactccaaat gttaatttaa tagtacgtgc ttatcttgat gataaattaa tacaaaacat
    13621 tactcctgtt gtacaaaatt caactttaac agcaacagta acagatagtc aactaaactc
    13681 tttatccgta gatggaaatc acaaactaaa aatacaatta aatgatggat atgataattt
    13741 tgatagaatt tttactttta aaaaaataga aaagggaatt gatatatcaa catcattagt
    13801 aactgatagc caagctaagt ttactgtaac aaaaatatac agtgaattga caaaaataga
    13861 gtgttattta gatgaaacat taaaagagac ttttactaca gacttgtatt cagaaaagac
    13921 tataaactat gaacttatag acaatgcaat acacacatta aaaatagttg taactgatgc
    13981 agaaaatgtt gtagaagaaa aagttataag tataagtaag aatataatgc cattgcaacc
    14041 tgatgcaaca ttacaagata tatcaactaa gttaacagag attgggcaag gcgttagaaa
    14101 tggtaaaaca agcattataa atactttagc attaaagaat atagatgcaa gtttaaataa
    14161 tacactcgtt gagttatcag agaaaattaa gggaggtttt gatagtggag acgctagttt
    14221 acaagatttg atgaatcaat taacacaagc taataatact atatcgcagt taaatactaa
    14281 gtataaagtt gctagtggta cagttacttc ttttgcggat agtactaaaa ttgcttatcc
    14341 atatctaacc gacaatgtta ctaaacctgg ttcttggatt aaagttagta atttaggctt
    14401 taaacctaat attttctttg ctgattttga ttactatgat gctgaatata aaaataatta
    14461 taaacttttc cttttcgctt gtaatggtgt tgccacacaa agaggtgttg atttttcaag
    14521 tgttacatct tttatcagaa aaagtggtga tgagtatttt catgctaatg gatggctata
    14581 tagtaactca gagggggatg tctattttaa taatactggc gttcagattc cagcttataa
    14641 ctttgattca actcaaaaac atacttataa atggtatgct attaaattta tttaaaagga
    14701 ggaaaaaaca tgaatgttcc aaaccgaata atatatgacc aaacaggtag aacaatcttt
    14761 gaaacaggcg aatcctgtgg agatgtattg ccacattata caataacgga attgcattat
    14821 atagatattg aatatggaag tatagattat acaaggaata gagttatagg tataaatata
    14881 gaaacaaaag aaccgatttt agaagaaata ccagtatata taacagatga ggaaaagaga
    14941 atacaagagt tagaaaatca attattaatt gcagaaaatg agaaagtagg aggattatta
    15001 taatgaatat aaataatgtt gtagtaagaa tattagcaga aagaatatta agtaagggat
    15061 taaatcctct aaaaaataga gaatttcagt tagatgacgt gactaacaca gagtacagaa
    15121 aagctgtaga ggattatatt ataaaaaata gtggagtagt agaaggagca gaaccaacta
    15181 tatagagggt tcttttttta ttgaaagaag gtgactaaat gacttttaaa gagttggtta
    15241 ataaagttag aaatcttgta ttagaagcaa agaatgtaac tatagaagat acagaaagta
    15301 aatttacaag tgaaaatgta gaaggagcat tgaaagaatg tatagataga gcagatgagg
    15361 cttttcaaga agccgatagt ggaaaaacac ttttatcaac tgctatcggc tctcctacta
    15421 catcagaaca aacatttcaa gattatgcga actatattac aggatttaag agcaatataa
    15481 gcaatttaga aactcaattg aaaagcaaat attctattag atatggtcct attgatggat
    15541 atgatggtaa tcctttttct gctaattttg gcaagagtgc aagttacctt attgtctatg
    15601 tttactttag aagaagtgta tattattata atcccagtgg tagttcttta ggaagtaata
    15661 caggaggttc tgaacgtgca tggattacta taaacagcaa taaaactggt ttttcagttc
    15721 attcatatga tactagttat gagtcatatc cttttacagg ttattatatt gcttgtttcg
    15781 cataataaat tatattatta aaactaggag gatgtatgga agaaattagc ataaatctac
    15841 tatgtgcagt agcaggagtt gtaatatcct acttagcatt tagaaataac tcaaacagaa
    15901 agatacaaga tgaaacagaa acaactacaa aattagaaca acaaataact tttttatgtg
    15961 agaatgtaag agatataaag catgatgtag caaagtttaa tactagtttc ttagatatta
    16021 gtgaacgagt tgcaaaaata gaagcaagta caaaacaagc acatcttaga attgatgaaa
    16081 ttgtaaatag aattggagga aaataagaga tggataattt aataagtttt ataccagagc
    16141 agttgctaat tttagtagct gctctctcta ttataggtaa aggttgtaaa aaatataaac
    16201 aattagataa taaatacatt ccagtagtgt tactgatact tggaataggt ttctcaatat
    16261 ggatgctagg attaaatcct gttgcagtct tacaaggtgt aatttgttgg ggagttgcaa
    16321 taggtataaa tcaaacttac aaacagttga aggatggtga aaagtaatga aattaacaaa
    16381 aatattatta ctcacaaaaa tttaaaaaat ttcattaaat agagtatact tttatagcta
    16441 ataagtatat aataatagta cagaactcgt aaagcattta tatgctcaaa tatacgggac
    16501 attgattttt gaaggaaccc gccaagcttc ttttatagct caaataggcg ggacagataa
    16561 atttacccac taatattaat tggtgggttt tattatataa aagtatatct atgaaaaggt
    16621 gaaaacaatg gttgaagtaa aagaagaaaa aacatttgat gaacaaatag atattttaaa
    16681 aagtagagga ttaataataa atgataaaga agatgctaaa tttgtattaa gtaatgtcaa
    16741 ttattatagg tttacagcat atcttctaag ttttaagaat gatgatggct catataaaga
    16801 aggaactacg tttgaagaag tttatgatat atataggttt aataaggaat ttaggatatt
    16861 attaacagat ttgttaggga gcatagaaat agcatttagg acatacattg catatacatt
    16921 agcaattaaa catggtgctt gtggatatct agaaagggag agtttcaaag atgaaaaatt
    16981 ctatattaat tttttgacag cattagagag agaaaaaagt aataattcag ataagctttt
    17041 tattatacac cataaagaaa aatatgaagg aaaacttccc atttgggttg caacggaaat
    17101 aatgactttt ggtatgttgt caaaattata ttcaaacatg ttgccagaag atactagata
    17161 cataaaaaat aatttgtgta gagtgaatac tttattagtt aaatcttggt tacaatcatt
    17221 aacacaggtc agaaatcaat gcgctcatta tggtagaata tataataata atttccgtat
    17281 tataacaata aaaaacgaat ataaaaagta taacttggat aataaaaaga tattttctta
    17341 tatacttgct atgaagcatt tgactatgga taaattaatt tggaatagtt tttttataaa
    17401 acttcaaaag ttaattaatg attataataa ttctatagac ttaaagctta ttggttttcc
    17461 taataattgg atagagatat tggctaaata aaatagttac tttaagaagt ttataaacac
    17521 ttactatatg taagtgtttt tttattgaaa agaaggagga aaataaataa tgaaaatatg
    17581 tattacagta ggacacagta ttttaaaaag tggtgcatgc acttctgctg atggagtagt
    17641 taacgaatac caatacaata aatctcttgc accagtatta gcagatacat ttagaaaaga
    17701 gggtcataag gcagatgtaa taatatgtcc tgaaaagcag tttaaaacta aagcagaaga
    17761 aaagacttat aaaataccta gagttaatag tggaggatat gatttactta tagaactaca
    17821 tctaaatgca agtgatggtc aaggaaaagg ttcagaagtt ctatattata gtaataaagg
    17881 tttagagtat gcaactagaa tatgtaataa gctaggtaca gtatttagaa atagaagagc
    17941 taaattagat aaaggattat atatcttaaa tagttcaaat cctacagcag tattaattga
    18001 aagtttcttc tgtgataata aagaagatta tgagaaagct aagaaactag gtcatgaagg
    18061 tattgctaag ttaattgtag aaggtgtatt aaataaaaat ataaataatg agggagttaa
    18121 acagatgtac aaacatacaa ttgtttatga tggagaagtt gacaaaatct ctgcaactgt
    18181 agttggttgg ggttataatg atgggaaaat actgatatgt gatataaaag attacgtgcc
    18241 aggtcagacg caaaatcttt atgtcattgg tggtgcagca tgtgagaaga ttggttctat
    18301 gactaaagaa aaatttacta tgataaaggg taatgataga tttgatacac tttataaggc
    18361 attagatttt attaatagat agattatata aaatatttta gtatttcttg aaaatcataa
    18421 gtatggtaat atttagataa atattattta ttattaatag gtatgggggg agattatgat
    18481 atttaagaag tatataaaat cattactgat agttgttagt gttacattga taatgaacaa
    18541 atcaatatta tttgtaaatg cattagattt agagagtaac aataacataa aatcttataa
    18601 aagaaagaat gtaaaggaaa ttgatataag caataaattt gttgatgaat cctttagaag
    18661 agatattgtt gaaaaggtat tagataatag ggatgatcca ttaacaaatg aagttgcatc
    18721 aaaagataac tataaaatat atgaaagtga tttaaataaa attgagagtt gcttagagtt
    18781 agatttacat aaaaatccag atgtttctaa tccaaacaaa atagataatt tagatgggat
    18841 agaaaatttt agaaatctag aaaagcttga ttgtagttca aataatctag aaagtgtaga
    18901 tttaagtaaa aatataaaat taaaatatct agatattagt ggaaataaaa tattaaacat
    18961 tgatttaaaa aacaataatc ttattaatga attacattgt gatgcaaata aattatcaaa
    19021 tttagacctt aaaaataata aaaatttggt aagtttattt tttactagta atgaattaac
    19081 agagatagat ttaagtaata atgtgaactt agaaaattta caatttctta ataataattt
    19141 aaaaagtata gatttaagtc ataataaaaa gttgaaatct ctaaattgta ctaacaataa
    19201 acttaaatcc cttgatttaa gtaataatgt ttttttgaaa aatttaagtt gttcaggtaa
    19261 taacctgagt aaattaaata taaaaggact tacaagtctt gagtatttgg gatgtgctaa
    19321 gaataaatta caagatttag atgtatctac aaatataaaa ttagattctt tactttgtgg
    19381 gaaaaatagt ttaacaaaaa tagatataag taaaaataaa gaattaaatt cactggaatg
    19441 tagtggtcaa tatatagaaa aaagcattat aaaaaatggt gaaaatatag ttgtagatat
    19501 aggaattgaa aattcgaaat taaaggaatt atatccacaa aattataata tttcaacagg
    19561 ttttctaaca tgggaaaatc tttctgactt tccaaatagc ataagttata gtttggaata
    19621 tgaatatggt ccagtaaatg atacagagac tatggatgta aatatatcaa tagataaatt
    19681 agtgaaatgt agaatcagat atatagatta tgatggaagt ataattaatg aaaaagaaat
    19741 atcagataat tctagtataa atgaaattca aattaatcct caaagagaaa actatgagtt
    19801 tagtggttgg aggaacaata aagatgaaaa aatatataca tcagagcagg taagtaaatt
    19861 agtttttgat gatagtactg attttatagc aacttataaa agaaaatcaa caggatcaag
    19921 tggttcttct ggtggaactt caagtaaaga agattttaat atagcaccat ctaaggaaaa
    19981 aataacaggt gcagacagaa atgaaacatc agtgaaaata agtcaaaaag gatggaataa
    20041 agctgataat atagtgttaa taaatgactc tagcatatcg gatgctttat cagcaacacc
    20101 atttgctaag tctaaagatg caccaatatt acttactaaa aataataatt taaataaatt
    20161 aacagaaaaa gaaataaata gattagaagc aaaaaatgtg tacatagtgg gtggattaaa
    20221 gtctgttgat gaaaaagtag tgtctgattt aaagaaaaaa ggattaaatg taattagaat
    20281 atctggaaat gatagatatg aaacatcaat aaaacttgca aaagaattag acaaaaattc
    20341 taacctgtca aaagtagtag tggtaaatgg agaaaaggga ctagctgatg cagtaagtat
    20401 gggagctata tcagcaaaag aggaaatgcc aattcttctt actaatcaaa atgatgatat
    20461 gaaagatata aaagacttaa tagctaataa aaacatatca aaatcatatg taataggtgg
    20521 agaatcttta tttaataata aagaagtgaa taatacatta ccatctgtaa ctaaaatagc
    20581 aggttctgat agaacagaaa ctaactcaaa agtaataagt catttctata gcaaagatac
    20641 acttaatgac ttatatgtag ctaagaatgg aatgaataaa caagacgatt tagtagatgc
    20701 cttatcagta ggagtgcttg caggtaaaac tgaatctcca gtagtattag ttggaaatgg
    20761 attagatgat agccaaaaag agttaatcaa gaataaaaag tttaaaaata taactcaaat
    20821 tggtggaaat ggaaatgaaa aagcatttaa tgaagtagaa aacttagtta aatagattga
    20881 aaggtagtaa ctggaaatag ttactacctc cttttttatt cattttcagt tttttcaata
    20941 attatttttc catcctcaaa agtaacaaga acatcccttt catcaggaga gatattcatc
    21001 tctttaatcc atgacattgg aagtatcaat ctgggtgtaa aagagccttt gccactttta
    21061 ttaaatccaa ttctaagttt tctttgctcc aataatatca ttcctttcta ctattaataa
    21121 atgccagcaa taataaagta aataccaaag caataagagc tttaaaagta aaacttatta
    21181 ttatattaat aatatttaaa actatagtga taccaagaat aatcatacaa attctataaa
    21241 atttattatt catattaaat tagaaaatgt gttataatat tagaaagaag ctacctagaa
    21301 ggaaggtatt ttcctcctag gattgaaact tataattctt taatcaatct tagtattgcg
    21361 agtactagat taattaaaac taatgtgaaa gagaaagcat ttttaatttt attaaatttg
    21421 ttttctcttt tattttttct tctttctaat ctccccactt tcttacctcc tttctatatt
    21481 tatattatat catcacgtga cgtgaaagtc aataaatatt acatattttt caataaagtt
    21541 atattgataa actatatttt ttacaaataa aaataaatgg tgacaaaacc aaacttgcca
    21601 ccattttgcc accgaaaata aataatagaa taaatttaaa ttaaacataa taaaacataa
    21661 acaacaaaac tgaccttaat aaaacattga aataccaaca cttgtaaaaa ataacaacaa
    21721 taaacaaata acctagaata atattacaac ttaagtaaat aataattttg aataataatt
    21781 tacggaggta ttcatatgtt taaacacgat aaagcattat taaaagaagt aaaagtagaa
    21841 agaccaaatc ctcaatatgc tgttttaatg caagaacagt tgggtggtgc aaatggagag
    21901 ttaaaagcag ctatgcaata cttgtcccaa agttttagaa taaaagaccc tcaaataaaa
    21961 gatttatttc ttgatatagc agcagaagag cttagccata tggaaatggt agcacaaact
    22021 ataaatttat taaatggaca tgatgttgat tataatgcag ttaatacagg cgaaatagaa
    22081 acacatgtat taactggtct atcaccagtc ttaataaact catcaggagc tccttggact
    22141 gctaattatg ttacagttac aggggattta gtagctgact tactttcaaa tatagcttct
    22201 gaacaaagag ctaaggtagt ttatgagtac ttgtatagac aaatagatga taaatatgta
    22261 aaagaaacaa tagatttctt acttaacaga gaagaagcac ataatgctct atttagagat
    22321 gctttaaata aagttaaaga tacaggttca aatagagatt ttggagttac agaagattct
    22381 agattatatt tcgatttgtc tactccaggg ccaaatcaca atactaagat agatattaat
    22441 cctccttctt ttgaaaaacc tttaaaaaaa taatttgata ttttttatgt tgttttgttt
    22501 tagtagttat aaaaattatt tactagaaga attaattata tgaaaaatta aatatgtata
    22561 gttaaaaatg ggtatacact tattataagt gtatatctat ttgtttattg caaaacatat
    22621 aataaaataa caaatgaggt ggtattttgg acagtaatag aaaacctaat aatctaataa
    22681 atgaaaaatc tccatatctt ttacagcatg cttataatcc tataaactgg tatagttgga
    22741 atgatgaggc ttttaaaaaa gcaaaagaag aggataaacc aatattttta agtgtaggat
    22801 attcaacatg tcattggtgt catgttatgg aaaaagaatc ttttgaagat gaagaagttg
    22861 ctgaaataat gaatagaaac tttgtggcaa taaaagtaga taaagaggaa agacctgatg
    22921 tagatagcgt gtatatgaca gtttgccaag ctatgacagg tagtggtgga tggccaatga
    22981 ccataataat gacaccagat aaaaaacctt tttttgcggg aacatatttc ccaaaatatt
    23041 caaggtataa tagacctgga gttatagatt tattaaagaa tgtatctgaa aaatggaata
    23101 caagtaggga tatattaata aaatctggag atgaaataat agaagctctt aaggatgatt
    23161 ttggtgtaaa aaatactgag ggtgatttat caaaagagat gttgagttca tcagttagag
    23221 tatttaaggc catttatgat gaaaagtatg gtggttttgg taatgctcct aaatttccaa
    23281 gtcctcagaa tcttatgttt ttaatgaaat attatagcat agaaaaagat aaagatgtgt
    23341 taaaaatggt ggaaaaaact ttagatggaa tgtatagagg aggcttgttt gatcatattg
    23401 gatttgggtt ttcaagatac tctactgata aaaagtggtt ggctcctcat tttgaaaaaa
    23461 tgctatatga taatgctatg cttactatag cttttttaga tgcatataaa ataacaaaga
    23521 aagagttata taaagaaatt gctataaaaa ctatagatta tgtagttaga gagatgaagg
    23581 ataaagaagg tgggttttat tcagcacagg atgctgatag tgaaggtgaa gaaggtaaat
    23641 tttatacatt taatcctctt gagataattg aagttttggg tgaagaagat ggaactttct
    23701 ttaataatta ttttgatata actagtagtg gaaattttga aggtaaaagt attcctaatc
    23761 ttataaaaaa taaagaatat gaaagacata atgaaaagat agctgacctt agtaaaaagg
    23821 tatttgaata tagaaaagaa agaacatctt tgcataaaga tgacaagata cttacatcat
    23881 ggaatgcatt gatgatagtt gctttaacaa aggcatatag tactttaaaa aatgacatat
    23941 atttagagta ttcaaataag tgtcttaact ttataaataa taatcttgta aatgagtcag
    24001 gtagattatt agctagatat agagatggaa gttccgacta tttagcatat ttagatgatt
    24061 atgctttttt aatctgggcg tatatagagc tttatgagtc aacatttaat atgaaatatt
    24121 tagaaaaggc tttaaatttg aatgaaagct gtatcaacct tttttgggat tatgaaaaaa
    24181 gtggatttta tatatatggt aaagatagtg aaaatttaat agcaagacca aaagatttgt
    24241 atgatggagc tattccatca ggaaattctg ttcaattata caatcttata agacttgcga
    24301 aaattactgg agataataga cttgaagaaa tgtcatataa acaattaaaa ctgtatgtgg
    24361 ataatgtaaa gagttctcca actggctaca gcttttatat gctttcattg atgtttgaac
    24421 tttattctac taaggaaatt atatgtattt ttaaggaaga ttctgattta attgcattta
    24481 aagaattgat aagtgaaaat tttataccaa atgcaacttt tttagcaaag aaatacaatg
    24541 aagaaaacac tattataggt tttttaaata actatagatt gaaggatgat aagactagtt
    24601 attacgtgtg tcaaagtaat agttgtagtc aaccaattaa tgatttacaa aaattaaaag
    24661 atatgatttt aggagtagaa taatcataat agcgaaaaag gagatgcttt aaaataaaag
    24721 tctaatcatc tccttttttt gtacaaaaaa cagaaaaaga gttcctaaga acacctaatc
    24781 tatgtaatga ttgttttgtt aaaaaataaa aatgacatta tagttatata aaatattgta
    24841 ctataaaaaa gtggtattat agatgcgata gtattaatcg tttttattta ccctatttct
    24901 tctttttgca aattcttcaa gtgcttcaga tttaatttta tctatttctt catattccat
    24961 aaaattagca tcttcttcaa agccatcttg ttcttcacca ttaaaacgat acattttttt
    25021 tagtaaactc cataaggtct ctaattcatc tttggtaaat tcgtgaaata catctgccat
    25081 aaagtttatt ccagtcctac tacatgttac cataaccttt tttcctaagt ctgtaacttt
    25141 aacattaatt gctctcttat catgaggact tggaattaca tcaacatatc catttttttc
    25201 aagattagca actagtctat ttatattttg tttacttgta cccatttttc ttgcaatatt
    25261 atttaatgtt gtttcttcct ctggtaaatg aagaattgat aaaatagtca tatactgtct
    25321 tgaagtaagt ataccaaaat atttatctcc ttctatttgt attttgtttg taagggtaaa
    25381 aagagttgca tatgtttgat tcattaaaaa gagctctttt agttcatttg aataatccat
    25441 gaaatatatc tcctttattt ttagaagttg ttttgtcgaa aacagaatat catgaattaa
    25501 ttctaatgtc aatatggtgt caaaatatat taaagtatta cttttttatg taactattaa
    25561 ttaaattatt gtataattgt atgtaaaaac ttctatgtac caatgataat ttctatgagg
    25621 aattaataat tcttaaattt tttagaaaga ttttgacttg aaaatacttg taatataata
    25681 tataaattaa tatactgaat aaaatcaatc tggagggata attatgaagt gtacaaactt
    25741 tactttcaaa ggagaggaag gtttagatat atatacatat aaatgggaag atgaaaatat
    25801 aaaaaaacca aaggcagtta tccaaattgc acatggaatg gctgaaactg cacaaaggta
    25861 tgagactttt gccaaggtac ttactaaaaa tggttatata gtatatatca atgaccatag
    25921 aggtcatgga aaaactgcaa agataataga aaatgttgga catttagctg aaaaagaagg
    25981 atttagatgt cttgtagagg acatgtatac tttaacaaat attataaaga aagaaaatga
    26041 agatttgcca atttatctat ttggacacag catgggttca tttgcaagtc aaagatatat
    26101 aatggattac agtaataatt tatctggtct tatactatgt ggttcaaatg gaaagcaagg
    26161 aatcattcta aatcttgctc atctgataat caatcgtgag attaaaaagt atggaagacg
    26221 ttctaaaagt aataaaataa ataatttgat taaaaaatag ctatgcacac ttgtgacttt
    26281 agtcatgagt tagtagctaa aatagtcagc atatagggaa acctatatgt agagatagga
    26341 tagaacctat ccaatactac ttgaattgct ggaaacc
//
LOCUS       DAMJWO010000059        26235 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.060, whole genome shotgun sequence.
ACCESSION   DAMJWO010000059 DAMJWO010000000
VERSION     DAMJWO010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26235
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.060"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(187..942)
                     /locus_tag="PC366_002491"
     CDS             complement(187..942)
                     /locus_tag="PC366_002491"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDF2577993.1"
                     /translation="MLKVIINGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHS
                     DTKLYKTMTDVTEKTDVIIDFSHHETLEPILSYALKNNTPVVLATTGYDENDLNKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVIFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLIGKQSGLYKMSDILG"
     gene            1383..2372
                     /locus_tag="PC366_002492"
     CDS             1383..2372
                     /locus_tag="PC366_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HDF2577994.1"
                     /translation="MLKEEKTYQEKDAKVFNGVAALIMIVLFLVVSIGIMVFGIVKLD
                     SGFTGIGSLMLILGLVFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAVSRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVINATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY"
     gene            complement(2643..3359)
                     /gene="dapD"
                     /locus_tag="PC366_002493"
     CDS             complement(2643..3359)
                     /gene="dapD"
                     /locus_tag="PC366_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HDF2577995.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     SNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLNEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(3583..4332)
                     /locus_tag="PC366_002494"
     CDS             complement(3583..4332)
                     /locus_tag="PC366_002494"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDF2577996.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDNEMNKIREAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            complement(4399..5286)
                     /locus_tag="PC366_002495"
     CDS             complement(4399..5286)
                     /locus_tag="PC366_002495"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDF2577997.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            complement(5403..6404)
                     /locus_tag="PC366_002496"
     CDS             complement(5403..6404)
                     /locus_tag="PC366_002496"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDF2577998.1"
                     /translation="MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     gene            complement(6829..7710)
                     /locus_tag="PC366_002497"
     CDS             complement(6829..7710)
                     /locus_tag="PC366_002497"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDF2577999.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPKDFAIYSGNDDTILPLLSLGGSGVISVLANICPKETHDL
                     VTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKQELTNFGFKF"
     gene            8033..9226
                     /locus_tag="PC366_002498"
     CDS             8033..9226
                     /locus_tag="PC366_002498"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HDF2578000.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            9432..10550
                     /locus_tag="PC366_002499"
     CDS             9432..10550
                     /locus_tag="PC366_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HDF2578001.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAIGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYSKLLKYKEAID"
     gene            10681..10926
                     /locus_tag="PC366_002500"
     CDS             10681..10926
                     /locus_tag="PC366_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HDF2578002.1"
                     /translation="MKEKVQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            10913..11659
                     /locus_tag="PC366_002501"
     CDS             10913..11659
                     /locus_tag="PC366_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2578003.1"
                     /translation="MSQYSDFAFVYDELMNEVDYNGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLTKKNYDIAGIDISDEMLSVAREKAEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKKDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENLIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLEK
                     SGFKDIKYYGDFTFDKPSEESQRIFFVCKK"
     gene            11944..12819
                     /gene="hslO"
                     /locus_tag="PC366_002502"
     CDS             11944..12819
                     /gene="hslO"
                     /locus_tag="PC366_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HDF2578004.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPDDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYSEEELLEILKEM"
     gene            13210..14010
                     /locus_tag="PC366_002503"
     CDS             13210..14010
                     /locus_tag="PC366_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDF2578005.1"
                     /translation="MESKTKYIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRELGVKPQNVIILADIDKKEGTHYELMEKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREGKIKDDLYFVKPKYVKYIPRNERAIYKAMDFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            14537..16777
                     /locus_tag="PC366_002504"
     CDS             14537..16777
                     /locus_tag="PC366_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2578006.1"
                     /translation="MSNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNDIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFAESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSRDGEISEATKKKLSKLLIEDRCPICDGRRLNEGVYRSLI
                     NGYNIADLTSMQIDELAEVIKSINEPEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHVVDVGPKAGKYGGKVVYEGSYKNLLTSGTLTGNALSKFLPIKESVR
                     EHSGYLEIKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPSAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNVCEGKKFKKEVLEYRFQRKNIIEVLEMSVLDAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIS
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIELGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAKYIV"
     gene            17191..18726
                     /locus_tag="PC366_002505"
     CDS             17191..18726
                     /locus_tag="PC366_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF2578007.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTAMTISGSILIALLALIFDFILGLVEKFFQRKRKKKNRKKV
                     FAILGSLILIATIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLNVEI
                     TQGIGGGTSNIQPAMENGEFDIYPEYTGTGWNMVLKKNELYTESMFSKLQSEYKTKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNISDLKNVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVIVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSEVFKMVGDILTDKEMAKMNYDVENNNLEPREVACEFLNKK
                     GLL"
     gene            18742..19503
                     /locus_tag="PC366_002506"
     CDS             18742..19503
                     /locus_tag="PC366_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578008.1"
                     /translation="MTPIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQTDIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKSAVNKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNTPANQFVDQLLNIRKSIIDDDNLKE"
     gene            19841..20709
                     /locus_tag="PC366_002507"
                     /pseudo
     CDS             19841..20709
                     /locus_tag="PC366_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438778.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
     gene            20903..21154
                     /locus_tag="PC366_002508"
     CDS             20903..21154
                     /locus_tag="PC366_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HDF2578009.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLETNDVVNWCKTKIE
                     SPNAIINRKGKNWYISVYDCIITVNAHSYTIITAHKEKK"
     gene            21266..22045
                     /locus_tag="PC366_002509"
     CDS             21266..22045
                     /locus_tag="PC366_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2578010.1"
                     /translation="MNNTVKEKLAESLTSDTTDILPYLPYLLQDFWELGSSPEQMLQL
                     FRKHIPFNEDTKVLDLACGKGAVSVKLAKELNIHIKGIDLIPEFIDYARRKAIEYKVD
                     ALCDFEMNDANSSVKIEHDYDCVIFGAVGDILGNYKETISKLLPTIKSKGFILIDDAY
                     VVDKSTNEQLNFERVYPTYNEWCILFKELGLKLIECIPCLELENDVEEEMNWIITRAN
                     ELIKKYPSQKDMFEQYVISQKNEYTDLQQDLVGATWILQKE"
     gene            complement(22180..22830)
                     /locus_tag="PC366_002510"
     CDS             complement(22180..22830)
                     /locus_tag="PC366_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578011.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSELKQLIQNDNKVFTFKVDSTSK
                     YPDALNAILNCDRLIIAFPLYVDGIPSHLLHFLEKCEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIDHWCKKINFTWVQGIGIGAGEMFGSLESVPLGKGPKKDLGIALKE
                     LSKNILSDNIHIDDSNKSTIFISPNFPRFLYKLMGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(22827..23330)
                     /locus_tag="PC366_002511"
     CDS             complement(22827..23330)
                     /locus_tag="PC366_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2578012.1"
                     /translation="MKLLIHDLTDKELEKLLPKLDDNIKILPNTKEIHKCIGRFGCWI
                     KTPSECVVKDYYSNMGKLINESDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKQINLKAIFYGDCITEAEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            complement(23379..23894)
                     /locus_tag="PC366_002512"
     CDS             complement(23379..23894)
                     /locus_tag="PC366_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF2578013.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGSKLKKLYSITNTGKEVFLEWLKKPINFSKTKQDHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKIDVEENHCIDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            24210..24701
                     /locus_tag="PC366_002513"
     CDS             24210..24701
                     /locus_tag="PC366_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2578014.1"
                     /translation="MRTIDIKGENMRELLKWVSIINRYNTNYIDRKLADIGINNSQYF
                     YVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGVKDKRTWHLYPTE
                     KSLECYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDMNEEAKLEAKENG
                     RKI"
     gene            24685..26088
                     /locus_tag="PC366_002514"
     CDS             24685..26088
                     /locus_tag="PC366_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2578015.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIVVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFVFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQFFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
BASE COUNT         9725 a         3232 c         4337 g         8941 t
ORIGIN      
        1 gactataaaa taataaacaa tataattcca tataccaata aataagataa tctttaagaa
       61 aaatgattat atttaaaagg taagcataaa atttataaac ttttagaata gaaatctcaa
      121 tcaattagat attcaaattg atgaatatga atacctaaat agattgagat ttattatgta
      181 caaaacttat cctagtatat ctgacatttt ataaagtcca gattgcttac caattaaaaa
      241 tttagctgca actatagaac cgtttgcaaa tacttcatca gattgagaat gatggcttaa
      301 tgtaagaact tcattatcac ctgcaaatat gacatcatgg tcgctgatta tattgccacc
      361 tcttatagag tgtattccaa tttcatttgg ttttctttta caatctctac catatctacc
      421 atgtgtattt tcactttcag gcaagacttc tctaattgca ttagctatca tagtagcagt
      481 tccactaggg gcgtcttctt ttctattgtg atgtttttct atgatttcaa tatcaaaacc
      541 ttctaacatc tttgaagcat ccttaactaa ttttattaat atattcactc caagagatgt
      601 atttgatgat aataatatag gaatgttttt tgatgcttct tctattttat ttaagtcatt
      661 ttcatcatat ccagtagtag ctaatactac aggtgtatta ttttttagag catatgacaa
      721 tattggctct aaagtctcat gatgtgaaaa gtctattatg acatcagttt tttcagttac
      781 atcagtcatt gttttgtaaa gctttgtatc actatgatga cctttttcat cagcagacct
      841 agctacacca caaaccaact ctaattcatt atcttttttt acacattctg ctaaaactct
      901 tcccattgtt ccattatagc cattaattat aactttcaat ataaattcct cctatgaaat
      961 taataaaaat ttgttatatt tctataagtt tattttatca ctaatattat ttatataaaa
     1021 taatattagt gataataagc ttacaattta tcttacatta aaaaaattta agtggatttt
     1081 tcaaaatata gataaacttc tttttcattg tataaatgat aaaaatatat ttgacttcat
     1141 atcaaaaaga gtgccccatg aactaaaaag ttaattttga gataccatat tcatatatca
     1201 tatgatttat ttggaaatca atattaatac attaaaataa ctaaatacat gtatgcataa
     1261 agatgtataa aaaatatata aacatatagt attaatttta aattcaacaa tttaattgtt
     1321 aaaagtgtta ttattaaatt agaaatatct taacttaata tactgagatg ggagtgatag
     1381 atatgttaaa agaagaaaaa acttatcaag agaaagacgc aaaagtattc aatggagtgg
     1441 cagctttgat aatgattgta ttatttttag tagtttcaat aggtatcatg gtttttggga
     1501 tagtaaaact tgatagtgga tttactggaa taggttcact tatgttaatt ttgggacttg
     1561 tatttatagt agtagatttt atcctatttt ttgggctaaa aatgattaat cctaaagaag
     1621 ctatagttct agttttgttt ggtaactatt atggaactat aaaaaaagaa gggtactatt
     1681 gggtgaatcc attttgttca gcaataaacc cagcagtatc aagaattaat gtatcgaaat
     1741 cttcatctga tgaaaaggta gatatatcaa ctaattcaag gggcaaaaaa gtatctttaa
     1801 aaacaatgac tcttaataat gaaaagcaga aagtcaatga tttattggga aatccaatta
     1861 taataggagt ggttgtaatt tggaaggtta taaatgcaac aaaggcagta tttaatgtgg
     1921 ataattataa tacattctta tctattcagt gtgattctac tattcgtaat gtttcaagac
     1981 tttatccata tgatgtatct gaagatggag atgaaaaatc tcttcgtggt agtagtcagg
     2041 aaatagcaga tagattaaaa gatgaattac aatcaagggt tgacattgca ggaattgaag
     2101 tgtgtgaagt gagaattact catctttctt atgcaccaga gattgcagca gcaatgttac
     2161 aacgtcaaca agcagaggct ataatagcag cacgtaaaaa gattgttgag ggggctgtaa
     2221 gtatggtaga gatggcattg actaatttaa gtgaaaataa tgttgtgact ttggacgaag
     2281 aacgtaaagc agctatggta agtaatctgt tagttgtgct ttgtggcaat aaagatgcac
     2341 aaccagtagt aaacagcagt tctatttatt aaattataaa aagtttaata gtttattaca
     2401 ttgatatatt gaaaaattga aggaaataaa aatacttgtc atcaagaaat aaaaatgata
     2461 taagaatgaa taagagaatt gtaaaaaaat aaaatgatta taaataaaag ataaaaatat
     2521 tataaaaaag agggtgcctc tgatgaatta aattcataca gagacacctt tttaattaat
     2581 tttttaaatt agtatattat tgtttaatta atctttctaa ttaataatat agtactattt
     2641 aattagtcta aatttctaag gtcttccata agcttagttt tgtcagccgt tttttcatct
     2701 ttcattttta taactttagc aggagaacca gcaacaacgg caccagcttc tacatcagta
     2761 gttacaacag caccagctgc aacaacagca cctttaccga ttctaacacc ttcaagaata
     2821 actgcattag ctcctattaa aacatcatct tcaactataa caggagtagc agaaggtggc
     2881 tctaaaacac cagcaacaac agcaccagca cctaagtgaa catttttacc aagagttcct
     2941 ctagctccaa taacagcatt catatctacc atagaacctt caccaataac agctcctata
     3001 tttataacag ctcccatcat tacaacagca tttttttcta tagtaaccat gtctcttatt
     3061 attgcacctg gctcaattct tgcatgttca tttaaagtat tttttagagg aatagcagaa
     3121 tttcttctat catattctac atgagtatct gttatatcat tcccatgttt atctaatact
     3181 tccattatat cctcatagtc acctacaaat atataagaac cattacttcc aaatacctta
     3241 aatttatcag ttgattggaa gtgtaaagag ttagtattta catatacctt aacaggtgtt
     3301 ttctttttaa cttcttttat ataccttgct atttcataag catcgtttaa atttaccatt
     3361 tgttaattct ccttgtattt cattatattt cttttattat atacttattt gtcaatttta
     3421 gtatatactt acttcttatt atttatattt tattttagtt agtttttatt gtatagacat
     3481 agtattaaat aaatttatta tatatgtttg atttgtattg cgtattatta tatctatatt
     3541 gcatatgttt aatttatatt gtgtattatt atatttatac tattatccca acatgctgtc
     3601 catattataa aatcctggtt tttgcttaac taagtatttg gcagcagcta tagaaccact
     3661 tgcaaagata ccacgagatt gagcttgatg gcttattgta agaacctcat tgtctccagc
     3721 aaatagagca tcatgttcgc caacaatatt tccacctctt atagcatgaa taccaacttc
     3781 atttggttgt ctttttgcac tacgaccata tctaccataa ttattttcaa cgtttggcaa
     3841 aacctctttt atagcgttag caatcataac agctgtgcca cttggggcat ctacttttct
     3901 gttgtgatgt ttttctatta tttctatatc aaatccttct agtaatttag ctgcatcttt
     3961 aaccaatttt actaatacat ttacaccaag agacatatta tatgattgga atacaggaat
     4021 aactttagcc gcttcacgta ttttgttcat ttcgttatca ttatatccag tagtagcaat
     4081 tactaaaggt gttttagtct ttaaaacgta agataagata ttatctaaat tagagtgatg
     4141 agaaaaatct ataactacat cagcttcctc aactatagta ctcatatctt cataaatttt
     4201 aaggtcgcct tcatagctat ccagacctct agctgcaaca caaaccaatt ctaattcatt
     4261 atcttctctt atagtatcgg ctaaaatctt acccattttt ccatcataac cagttgctat
     4321 aacttttaac ataatttcct cctatgatta agggctaact tttgaccaaa cttacttttt
     4381 accatgcatt aatctttact atgcattaac ttttagtcca aagttaacta attctttctt
     4441 taacacttct aaatttgctg ggtccatttc tgctagaggt aatcttaaat ctccaacatt
     4501 gaatcccaat aaattcattg cagtcttaac tggtatagga tttacttcta taaataaagc
     4561 tgcgattaga gcatccatac caagttgtaa ttttctagaa ccttcaatat cgccttcaaa
     4621 gaatttagct accaaatcgt gagtttcttg agggcaaaca ttagcaagta ctgatataac
     4681 tccttgacct cctaaagata ataaaggaag tatagtatca tcattaccag agtagatagc
     4741 aaagtcatct ggaactaaac tagctatttc tgcaacttgt cctaggtctc cactagcttc
     4801 ttttacagca actatgttat caattttagc aagttcaact ataaggctag gacttatatt
     4861 tacacaagtt cttccaggga cattgtaaag tataattgga agtttaacac tgttagctat
     4921 tgtttcaaaa tgacgcttaa gtccagcttt attagcttta ttgtaataag gtgttattat
     4981 taatagagca tctactccta atttttcagc ttcttgactt aagttaactg agtgcatagt
     5041 atcattagaa ccacttccag ctataacagg aactctttta ttaacttttt caacaacata
     5101 cttaatagta gcaagttgtt cttcatcagt catagtatta gcttcaccag tagtaccaca
     5161 agatactata gcatcagtac cattagctat ttggtattca actaattcac ctaatttgtc
     5221 aaaatcaact ttgttatcct ttgtaaatgg tgtaactaga gcaacagcag aacctttaaa
     5281 tatcatataa aatcaatccc ctctttttta tttttgtgtt ttatattaca gttacttcta
     5341 atgcttgttt ttgagttact attaatattt tacaaaatta tatatttata caagtttgta
     5401 tattatacta aatcgtatga taaagccatt tcagctattt gaattgcgtt agttgcagca
     5461 ccttttctta tattgtcagc aacaacccaa agatttacac cattatcaac actaaaatct
     5521 cttcttattc ttccaacaaa tacttcatct ctatcatcaa attctacagc agttggatat
     5581 tcgtttttag caggattatc aactactaca acacctggag cttcttcaag tgtttttact
     5641 aaatcatcta actcaaatgg attgttaaac tcaacattta tagattcact atgaccattt
     5701 tttactggaa ctcttacagt agttgcagtt atttttaaat catagttatc aagtattttc
     5761 atagtttcat ttaccatttt catttcttct ttagtgtatc cattttcagt gaatgaatct
     5821 atatgaggaa gacagttgta agagatttga tgagggtaga atccagtagg attaccgttc
     5881 attcctttct ctaaatcttc aacaccttta acaccagaac cagatacagc ttggtaagta
     5941 gagtaaacaa ctctcttaat tttgtattta tcatcaagag ctttaagggg aaccatagct
     6001 tgtatagtag agcagttagg attagctatt atacccttat gattttttat ggcttctgga
     6061 ttaacctcag gaactactaa aggcacatct ggattcattc tccattgact agagttatct
     6121 actactaaga ttccatttga agcagctatt ggagcatact tttcactaat acttccacca
     6181 gcagagaata atgctatttg tatgcctcta tcagtaaatg aagtttcctt taattcttct
     6241 actatatatt ctttaccaca aaacattact ttagaaccag ctgatttaga agaagagaat
     6301 aaaaatagat tttctattgg aaaatttctt tcttctaata cttttaaaaa tgttctacct
     6361 accattccag tagcaccaac tattgctaca tttacttttt tcatataaat tcaccccaat
     6421 tttaaattat taaaacatta ttttatttta gttatacaag taagatatgt taatattttt
     6481 atatatccaa aaactttaat attatattaa caactttaat tatatacaaa aaacgtacaa
     6541 aggtatactt tgtacgtcta atttatcact caaagtaaac cctgtagctc atcacctaca
     6601 aaaataagtg acagtattac acatgttatg tgcaatccca gaaaatatta ttgcaagaaa
     6661 tattttcttc ggctgtaaat cctttttcca atcattaaca cctgccagct actattggat
     6721 actcttagtt acagctacct ctaccctagg ttaataggat attaaaattt gattattcta
     6781 ataataatac atatttaaga aaaaatcaac ttatttatat aaatattgct aaaacttaaa
     6841 tccaaaattt gtcaattctt gttttaacac attaagatta gtttcttcca tttcagctag
     6901 aggaagtctt aaatcaccaa cattaaaacc taaaatgttc atggcagttt taacaggaac
     6961 tggatttact tctataaata aagcagcaat taaagcatcc atatcaagtt gtaatttttt
     7021 tgagccttca atatcacctt caaagaattt agttactaaa tcatgtgttt ctttaggaca
     7081 tatgttagca agtacagaga taacaccact tccacctaat gataatagtg gtagtatagt
     7141 atcatcatta ccggagtata tagcaaagtc tttaggtact aatttagcta tttctgcaac
     7201 ttgagctaag tctccacttg cttccttcac agcaactata ttatctattt tagcaagttc
     7261 ggccacaaca gatggcttta tattcacttt agttcttcct ggtacgttgt ataaaataat
     7321 tggcaactta acgctatttg ctattgtttc aaagtgaagt ttaagacctt tctcattagt
     7381 cttattatag taaggagtta ttattaaaag accatccacc cctaattttt cagcttcttg
     7441 actcatatga acagacaaca tagtattgtt tgaaccagta cctgctataa caggtattct
     7501 cttattaact ttttcaactg tatattttat tacagcaaaa atttcagatt cactcatagt
     7561 agtcgcctca cctgttgttc cacaaacaac tagtgcatct gtgccattct caatgtgata
     7621 ttcgattaat tcacctaatt tttcaaagtt gacattatta tcctctgtaa atggggtaac
     7681 taaagcaaca gcagaacctt taaataacat ataatcaaat ctcctttttt atctaaattt
     7741 aattttttaa gtacaataat aattatagta caaattaatt aattttaata ggtatagtta
     7801 atatcttaac tgtttaaata agatatttat attatattaa tattagaaaa attttaaata
     7861 aatgttttat tctcaaaata tgcatattaa tttaataaaa tataccaaaa tggaaataaa
     7921 aaataaattt tatgagaatt taataactaa taattaatat atttaggtta taataaatat
     7981 gtgcgtaaaa tctaacaata agcaataata ccgtaaattt aggaggaata atatggatac
     8041 tttaaaggaa ctttttaaaa taggaagtgg accttcaagt tctcatacta tgggaccaca
     8101 aagagcagca gagagattta agaatgaaaa cccagatgca gaaagtttta gagcaatatt
     8161 atatggtagt ttggcagcta cagggaaagg tcacttaact gactatataa ttgaaaaaac
     8221 tatagcacct aaaaaagtcg aaattgtttg ggaagaagat attataaaag attttcaccc
     8281 aaatgggatg aagtttgaag ctttagataa agataaaaat gtaacagctg aatggactgt
     8341 atattctgta ggtggaggga ctatagcaga agaaggtcaa agaaacagta aaagcaatag
     8401 tatatatcac ttagatacta tggatgagat agtaaaatgg tgcaaagaaa ataataagac
     8461 tttggtagat tttgtgttgg aatgtgaacc aaaagacata aaagattata taaaaactat
     8521 aaaagatgct atgagaaaat ctattgatga tggactaagt acagatgaaa taataccagg
     8581 caagttatta ttaaaaagaa gagcaagtac attttataat gcatataaaa aagataagag
     8641 cttctcaaca cttgtatatg catatgcact agcagcttca gagcaaaacg cttctggtaa
     8701 tataatagtt acagcaccaa cttgtggttc tgctggagta ataccaggaa tattctttgc
     8761 aatgcaggat ttctataatt atgatgacga aaaaataatt gaagcactac ttgtagctgg
     8821 aataataggt aatataataa aaactaatgc ttcaatatct ggagcagagg tagggtgtca
     8881 aggtgaagtt ggagcagctt gttctatggc agcagcagca gtagcatact taaaaggtgg
     8941 aactatagac catattgaat atgcggcaga aatagcactt gaacatcatt taggaatgac
     9001 ttgtgaccct gtatatggat atgttcaaat tccatgtata gaaagaaatg caatggcagc
     9061 tcaaagagct tatgatgcag ctaattatgc attattaact gatggctcac attctgtctc
     9121 cttagaccaa gttgttgaaa caatgaaaga aactggtata gatatgatgg ataagtacaa
     9181 agaaacagct aagggtggac ttgctaaaca tttcttctct tgctaaaaat aaaattttcc
     9241 aataataatt cctctgtttt gatttatgaa acaggggaat tattattaat ggtgaattat
     9301 ttaataatgc aaaatatttt tatattcaat ttagcttttt atttttaatt agtataacat
     9361 gctatataat attttaatta taaagaaata tagaaatatt ttttaataaa ttagaaattg
     9421 gaggagatta catgagagag gcatcatatt tacaagaaca actttataaa cataggaagt
     9481 cattaaatcc tattgcagag attgggagaa aagagtataa gacttcaaaa tatataagag
     9541 attatcttga taaattagga attgagtatg aagtttattt agaaacaggt atagtaggtg
     9601 taatagaagg taaaagacct aaaaaagata ttgcttttag agctgacata gatggtcttc
     9661 atagtgaaga aggggtaaaa catttatgtg gtcatgatgg acatgctact atattacttg
     9721 gattaattga gtatttaaat gataataaag aagacttaaa tgataatata gtatttatat
     9781 tccaaccagc agaagaaggt cctgggggag caaaagcttt aatagatgaa ggagtgctta
     9841 gaaaatacaa tattgatgaa atatatgggc ttcatatata tccagagtta ccagaaggtt
     9901 atgtaggtac aagagaaggc tattttatgg ctcaaatagg agatatcgac atagaaatag
     9961 tgtctaaaag tggacatggg gctatgccac aaaatggtat tgatggtata gtgatagctt
    10021 caaactttgt aagctcactt caaactatag tgtctagaaa tataagccca atagacaatg
    10081 cagtgttgac tattggtaga attgaagggg gagctagaag aaatataata gctgaaaata
    10141 taaagatgga aggtactatg agatgtttca gcccagaagt gtatgagaaa atgaagctta
    10201 gagttagaga acttgctaga gggtttgaat tggcttataa ctgtaaggtt aatataaata
    10261 ttatagatga ttatattgct gttaaaaatg acaaggattt gtatcaagag tttgtagagg
    10321 ctattggaag tgatactgtt gtagagttag agccacttat gatatcagaa gatttttctt
    10381 attatcaaaa agaagttcca ggattatttt ttatgttggg ttcaagaaac gaagaaaaag
    10441 gatttgtaaa tggtcttcat aatataaact ttaattttga tgaaaagata tgtgtaaatg
    10501 cattgaatgt ttattcaaaa ttattaaaat acaaagaagc aatagattag gaagataaat
    10561 tataaagatt aaaaagcata aatacctaaa tttaaaaaaa atgtattaat aaatacccct
    10621 tatatatttg tataaattta ttttaattga caaaaataca aataagaagg ggtgattttt
    10681 ttgaaagaaa aagtacaaag agaaaagaag ataactaatg gcaagaatac taaaatattg
    10741 acaaatgatg atataatgaa atatgagata gcctcagaac taggtcttat ggataaagtt
    10801 ggtgaacgtg gatgggcagg acttacagct aaggaagcag gaagaattgg aggtatgctt
    10861 acatcacgca aaaagaggct taaaaagatt gtggaggagc agaataaaaa ggatgagtca
    10921 atatagtgat tttgcgtttg tatatgatga acttatgaat gaagttgatt ataatggttg
    10981 ggttaaatat atagaagata taatagatag tgaaggtgta aaagtaaaaa atatattgga
    11041 attggcatgt ggcacgggta atcttacaat tccattgact aaaaaaaatt acgatatagc
    11101 tggtatagat atatctgatg agatgcttag tgtagcaaga gaaaaggcag aaaaagaagg
    11161 agtagaatta gttttacttc aacaagatat atcagagctt gattttgaaa tatctgattt
    11221 ggactgtgtg ctttgtgctt gtgatggatt taattatata acttatgatg atgatttgga
    11281 aaatgtattt tcaaagacat atgaattatt aaagaaagat ggaatattca tatttgatat
    11341 aagttctttt tataaattag ccaacatatt gggaaataac atgtatggag aaaatagaga
    11401 agatatagcg tatatgtggc aaaattactt tgatgaagaa gagaatctaa ttgaaatgga
    11461 acttacattc tttattaaag atgaatgtgg aaagtttgaa agatttgaag agatacacca
    11521 acaaagagca tatactgaag atgagatagt tgatatgctt gaaaaatctg gatttaagga
    11581 tataaaatat tatggggatt ttacatttga caaacccagt gaagaaagtc aaagaatctt
    11641 ctttgtatgt aaaaaataag atatttttga ctatataaga taattattaa aaataaccat
    11701 gatataaaaa tatagaaaat gcagttttat agattaaaag taaagtgatg atactttatg
    11761 acttttattt tctaataatt ataaagttct atagataaaa attaaaatat aataactatt
    11821 gcttagtaaa attaaaataa aatgggtttt gcccaaggtt aatatagata agtacttata
    11881 gattaaaatt aaggtagtaa tataataaaa ataagacaat taacgggaca tggaggaata
    11941 ttaatgagag attatgtact aagagcgaca tcaggaaatg gtcaagttag agcatttgtc
    12001 gcaactacta gaaatacagt agaagaagct agaagattac atgaaactac aaaagtagca
    12061 acagcagcac ttggaagaac attaacagcc acatctataa tgggattaat gatgaaaaat
    12121 gatagtgata aattgactgt aataataaaa ggtggaggtc caattggaac tattatcgcc
    12181 acatcagatt ctaagggaat ggtaaaagga tatgtaggaa atccacaagt agaggttgaa
    12241 gactatccaa atggaaagtt aaatgtagca gcagcagtag gtacagaagg tgttgtaaaa
    12301 gttataaaag acttaggtct tagagaacca tataatggga cttatccatt ggtaagtgga
    12361 gaaattgcag aagactttac ttattatttt gctgtatcag agcagactcc atcagtagta
    12421 gctttaggtg ttcttacaaa agaagatgaa gtagagtttg ctggaggatt tatagttcaa
    12481 ttaatgccag atgcagaaga agagactatt gctaagttag aggaaaatgt agctaaatta
    12541 ccttctataa ctaacatgtt aaaagaagga aaatcaccag atgatatatt aaatattgtt
    12601 ttggatggtt tggaacctaa aatacttgat acctgtgaag tagggtttat gtgtgaatgt
    12661 tcaaaagaaa gagtaaaaac tgctttggtt gcaattggta aaaaatcatt ggctcagata
    12721 atagaagaag ataaaaaagc agaagttggt tgccagttct gtaataagaa gtatatgtat
    12781 agtgaagaag agttgcttga aattttaaag gaaatgtagg ctataaaaat agttgtattg
    12841 atataagtaa tgttatagtg atatagtaaa gtcgtattga tatagtaatt aaagtataat
    12901 ttattaataa tagacatatt tatattaaaa aataaattta ataaattttt aagcttaata
    12961 aattttaaga attaagaagc tttctggctg taatatttgc aatgttgcag ttagaaggct
    13021 tttttatttt attatagttc gtgtcaaaga ttgtatgaaa caataaaata ttgtaaaata
    13081 atttgtatat ttagacctga ttgacacaaa ggtttataag atatttgagt tgattatacg
    13141 aaattctatg aagtagtaac cctgtgactt taatcatggg aggttcagaa gaaggagaaa
    13201 attttaaata tggaaagtaa aacgaagtac ataggaataa gtatattaat attattgatg
    13261 atatttttaa ttgcaaagaa ttttaacgga aaacttgaaa tacctattcc tgagagtaat
    13321 agtagaaaat ttaaatcagc agcagtgttt tatcctcaac atcaagatga tgaggtttta
    13381 tggggaggaa gtgccattgt agatgctata aaacagtgtg gtgttgataa tgtatatgtg
    13441 gtattagtat cagatggttc tggagttaac gttttcaaag ctaacacaaa atttagaaac
    13501 ttaactagga agcaaaagga agagcttaga aataatgagt ttaaatcagc tttgagagag
    13561 cttggagtga aacctcaaaa tgtgattata cttgcagata tagataaaaa ggaaggcaca
    13621 cattatgaat taatggaaaa gactatattg gattttgaac ataagtttaa aggcaatgtg
    13681 acccatatag cccatcacta taagtatgat gaccatataa tgcatagaaa gaatggggaa
    13741 gttttaaaga aacttaaacg tgaaggtaag ataaaagatg acttgtattt tgttaagcca
    13801 aaatatgtaa agtatatacc aagaaatgaa agagctatct ataaagcaat ggattttgat
    13861 gactacaata aggttaagag tgcttgttat gaatataagg ttgtaaattc aaagcgtaaa
    13921 atgtatggta taggatatat ttcggcacat agttattttg aacatcttct aaatgaccct
    13981 gaacttacgt ctgtattaag tgaagattaa tttcttataa gtagtaagtt atgtttgata
    14041 agttgattgg aattttctat agttttgaag gtattggaaa tttagtttta tttaaagatt
    14101 taaagataga ggtttttaat gtttaaaatt ttaaagttaa gttgaataat tgtatagaat
    14161 tatttgtgaa agaagaaaca gtgtaaaaca tagtatctta tttatggttt taaaatcata
    14221 ggcaagatac tttttttatg taactaatac cattttgagg ttattaactt aagaatttta
    14281 tataatttaa cactcatata taatgatgat atttaggtag aatagatgca attacgctta
    14341 aataaaataa ctgtattttt tataaaaatc aaaccctaca ctatactacc agataaaatc
    14401 tacatgctat aatttgacct gtgtttataa aaaaaggagt aatctaataa aatagtattt
    14461 cacttatgta taactaacaa ctattattac gattttctct aaataattta aagaaaaata
    14521 atgcaggagg taaaatatga gcaatgaatt tataatttta aaaggttgca aagagaataa
    14581 tttgaacaat atttccttaa aaataccaaa aagaaaaata accatattca caggggtgtc
    14641 gggttctgga aagtcatcta ttgtatttga gacaattgca aaagaatcac aacgccaact
    14701 aaatgaaagg tttagtacat ttgtaagaag ttttttacct aagtatggag aggttaaagc
    14761 tgattgtata gaaaatctgt caacaccaat tatcatagac caaagtagac ttggtggaaa
    14821 ttcaaggtca accctaggta ctattacaga tgtaaattcc tttttaagag ctttatattc
    14881 aaggtttggt agtgagtata taggtaatgc taatatgttt tcttttaatg atattgatgg
    14941 tatgtgccca cactgtcatg ggcttggaaa aaagctagtt cctaatatga accaaattct
    15001 tgatatgaat aaatcattaa atgaaggtgc tatattgctt tcagggtttg gagtgggttc
    15061 ttggcattgg aatatattcg ctgaatcagg attttttgat attaataaga ggatatgtga
    15121 ttattcagaa gtagaattgg aaaagttttt gcatggtaaa gcagaaaaga ttaagataga
    15181 aaatgctggt caaactaaca tgacatatga gggattaatg gttaaattta atcgtctata
    15241 cttaagtaga gatggagaaa tatctgaggc tactaagaaa aaattgagta aacttcttat
    15301 agaagataga tgtcctatat gtgatggaag aagacttaat gaaggagtat ataggtcttt
    15361 aattaatggt tataatatag cagatttaac tagtatgcaa attgatgaat tggctgaagt
    15421 tattaaaagt ataaatgagc cagaagcaca acctttaatt aaaggaataa tagaaaagtt
    15481 aaacagtatc atagatatag gtcttggata tttaacactg gatagagaga catcttctct
    15541 atcaggaggg gaatctcagc gtataaagat ggttaagtat ttaaatagta atcttgttga
    15601 tttaatgtat atttttgatg aaccaagtgt aggacttcat ccaaaagatg tgtataaatt
    15661 aaataatctt ttaaaaaaat tgcgtgataa agggaataca attatagttg ttgaacatga
    15721 cccagatgtt attaagattg cagaccatgt tgtagatgta ggaccaaagg caggtaagta
    15781 tggtggaaaa gttgtgtatg aaggcagtta taaaaatcta cttacaagtg gtactttgac
    15841 agggaatgct ttaagtaaat ttcttcctat taaagaaagt gtaagagaac atagtggata
    15901 tttagaaatt aaaaattgta ataaaaacaa tttaaaaaat gtatctatta agatacctaa
    15961 aggtgtattg actctagtta ctggagtagc aggagcaggt aaaagtacgt tgattaagga
    16021 tgaattttta aagcaaaatc ctagtgctgt acttatagac caaagccctg tttcagcaaa
    16081 ttcaaggtcg agtttggcaa catatagtgg aattatgaac aacataagaa gcatattttc
    16141 aaaaacaaat ggcgtaaatg cttctttatt cagttcaaat tcagaaggag cttgtgataa
    16201 ctgtaagggt tctggaatag tagaaatgaa tcttgctttt atggagagta taaagagtac
    16261 ctgcaatgtt tgtgaaggta aaaaatttaa aaaagaagtt ttagaatata ggtttcaaag
    16321 gaagaatata attgaagttc ttgaaatgtc tgttttagac gcaattgagt tttttaattt
    16381 aaaacagatt aaaacgaaat tacaatgtat tgaaaaaatg ggtattggat accttacttt
    16441 aggacaaact cttgatactt tgtctggagg agagtgtcaa agattaaagc ttgctagtga
    16501 attaaataag gaaagttcag tgtatatatt agatgaacca acaacaggtc ttcatatggc
    16561 tgatattgag aattttataa gtataattga agagattgta gataatggaa atacggtcat
    16621 aataattgaa cacaatatag atgtaattaa aagagctgat tggattattg agctgggacc
    16681 tgaaggaggg acaaaaggcg ggagagtaat atttgaaggt atcccaaaac aattatgtaa
    16741 caataaaata tcattaacag caaaatatat agtataataa ataaaatata ataaaattat
    16801 aatgatattt taataaatat aatgggtata taaaatgata attaaactta acagtaataa
    16861 ataatgtgag aaatattcaa atttaattaa ataaagtgtc agaaatttgt ttaaatttta
    16921 gtattttaac gattctgacc ttttttctta tttttatgga gagtatcgaa gatggagtct
    16981 ctaatagtta cttttttgtg tctacttgca agtttgatta aaaaatggct atacacactt
    17041 gtgacttcag tcatgggagg ttcagattat aatcttaata tataatttgt gaaataattt
    17101 gatgacgatt tgctgatgta taaacaataa agattaacta cattaaaatt taaatcttgt
    17161 taagtaaaac ttataaaagg agagagatgg atgataaatg atattctaac cttattatct
    17221 gaaagaagtg atttttttat aaagctatcc atagaacatt tgatgatttc tattatttct
    17281 ataataattg cgattgtttt gggtggtata attggtatta ttgtaagtga atttcataat
    17341 tcttctaaac ctatattggg aactatcaat tttctataca ccattccatc tatttctatg
    17401 ctaggatttc tgataccatt ttccggaatt ggaaatacta ctgctgttat tgcacttacc
    17461 atttatgcat tattgccaat ggttagaaat acatatactg gaattactaa tgtggataaa
    17521 aatattcttg aagcagctag gggaatgggc agtacagatt ttcagatatt gtataaaata
    17581 aaacttccat tagccctacc tgttattatg tctggtatta gaaatatggt gattatgaca
    17641 attgcattag ctggtatcgc ttcatttata ggtgctggag gcctaggtgt agccatatat
    17701 agaggaatca cgacaaataa cacagcaatg acaattagtg gaagtatact tattgctcta
    17761 ttagctttaa tatttgattt tattttaggg ctggtagaaa aattttttca acgaaaaaga
    17821 aaaaagaaaa ataggaaaaa agtttttgcc attctaggaa gccttattct tatagcaact
    17881 atctttacgt cttatttatt taatccttca aagactcaaa ctattcatat tgctactaaa
    17941 cctatgactg aacaatatat tcttggtgag atgttggata ttttaattga aaaaaacaca
    18001 ggtctaaacg tggaaattac acaaggcata ggagggggaa catctaatat ccagccagct
    18061 atggagaatg gagaatttga catttatcca gagtatacag gtacaggctg gaatatggta
    18121 cttaagaaaa atgaattata tactgaaagt atgtttagta aactacagtc ggaatacaaa
    18181 actaaactta aaatgcaatg gactggtatg tatggttttt ctaatagcta tgcattagca
    18241 gttagaaaag aagttgcaga taaatataat ttaaaaaata tatcagactt aaaaaatgta
    18301 tcttctaaat tgacatttgg agctgaatat gacttttatg agagagagga tggatatact
    18361 ccattgtgta atacatatgg actgaacttt aaagatacag ttgatttaga tattggatta
    18421 aaataccaag ctatcaatga aggtaagatt gacgtaatgc ctatatttac aactgatggt
    18481 cagtatagtg tttcagatgt tatagttcta aaagatgata aaaatttcta cccatcttat
    18541 caatgtggaa atgttgttcg tttggaagta ttagaggaaa atccagaact atcagaggta
    18601 tttaagatgg ttggagatat tttgactgat aaagaaatgg ctaaaatgaa ttatgacgta
    18661 gaaaacaaca atttagaacc tagagaagtt gcttgtgagt ttctgaataa gaaaggtctt
    18721 ttataaattg gaggaaatat aatgacacct attatacaat ttaaaaatat taaaaaacaa
    18781 tataatgata aaactataat agataatctt aatttagata tagaaaaagg agagtttttg
    18841 actgtaattg gttcgtctgg ttctggtaag acaacactct taaaaatgat taatggtctg
    18901 attttgccag atggaggaaa tattttgata aaccaaacag atatcaaaaa cgaggactta
    18961 attaaattaa gaagaagaat aggatattgt gtacaaggaa gtgttctttt tcctcatatg
    19021 actgttgaag aaaatatttc atatgtacca aatctcctaa gtaaaaagaa taaattagaa
    19081 gtaaaaagtg ctgtaaacaa gtggatggaa atagtgggat tgccaaatga tatgaaagtg
    19141 cgttacccat cagaattgtc aggtggtcag caacaacgtg tagggattgc aagagcttta
    19201 gcttcttctc cagaaatttt attaatggat gaaccttttg gtgcagttga tgagattaca
    19261 cgaaagcaat tacaaaaaga gataaaagaa attcataaaa aaacaggagt tacgattatc
    19321 tttattacgc atgatattta tgaagctttg attttgggaa caaagacttt ggtattaaat
    19381 catggagttg ttcaacagta tgatactcct gagaatattt taaatactcc tgctaaccaa
    19441 tttgtagacc agttattgaa tataagaaaa tctataatag atgatgataa tttaaaagaa
    19501 taaatttaaa tttaaaatca aattgttgtg ataaaaacta ttgatttaga gctaacttca
    19561 agttgtatac ttgaagtgga aaagttagat taaggtatag aagagaattt agcagttggc
    19621 tgtagacgag gtaactgctg aaggtgcttt caataaatgg ctagaacctg tatctattga
    19681 agattataat aaattgaaat aagaagctca atatacagag tagataggca cttcaaatag
    19741 aagtgtcttt tgtgtgccat aaaataaatc aaaatattag caaagaatgt gaaaaacaaa
    19801 ataaaataat atgctatctt taaaatagga ggggtgctat atggataaca atttgattac
    19861 cattgaaaaa actttagatt atatagaaaa acatctttta gatgagatgt tagatttaaa
    19921 tgtaatttct aaagagatag gctattcaaa gtaccattta catagaatgt ttacatcagt
    19981 tgtcggattt agtatacata attatataca aagacgtaga ctaactgaag cagcaagaat
    20041 gctcattttt acagaaaaac caattattga aattgcttta atctcggggt atgacacaca
    20101 acgttctttt tcaacagggt ttaaaaaaat gtttaagcat agccctaagt tttttagaaa
    20161 acatcaagat tttttaccac tacaattaaa atttgatatt aataatagaa aaaggttaca
    20221 tggaggtatg gttttagatg ttaaaaaagt taattgtaca gatataaata ttgttggcta
    20281 ttctggtaaa gtaaaaaaag gatttcatgt tattggaaaa tgttggaggg atttgcataa
    20341 aaataaagag ttgatagaaa acaaggtaga cttggatttt ttaattggag ttaatgatta
    20401 tagtaatttt aaagaaattg aaaataatcc tacatttaca tatattgcag gtgttcaagt
    20461 agctactttt ggtaaattcc taatggaatg gaaaaattcg tattaccgaa aagtaattat
    20521 attgttttta cttttattgg gaaaaatgag gatagtatgc aaaatgttgt agaatatatc
    20581 tatcaagaat ggttccttaa ttcaagttgc cagtttaatg aaaataattt atatgatttt
    20641 gtaaaatacg gagaaaaaac tgataagaat ggtttgagtg aaattcagtt ttgggttcca
    20701 atcatttaaa agaagggatt atgtataaag taggtggatt tatataggca aagttttata
    20761 aaagtatgta tttataaata atttatagtc tgtaggaaag aaatagtttt actataagat
    20821 tatgataaaa tacacaatac tatgataaaa tagtactaaa taatagattt aattttgcaa
    20881 aggataaagt gttttaataa aaatgaatgt agaaaacgaa ttacttaaaa acctagatag
    20941 attgcataca acagagttag gcgttgtaag aattaagaaa aatctttctt tggagacaaa
    21001 tgatgtagtg aactggtgta aaactaaaat agaatctcca aatgccatta ttaatagaaa
    21061 gggaaaaaac tggtatataa gtgtatatga ttgtattata acagtaaacg ctcacagtta
    21121 tacaattatt acagctcata aagaaaagaa atgaattgaa aaatacaaag gtcaaaagca
    21181 ttttccactg tttgtagtac ctatgaagaa gtatataaaa taatattact tttgaataat
    21241 aatttaaatt ttggaggttg aaaaaatgaa taatactgta aaagaaaaat tggcagagtc
    21301 actaacttct gatactactg atattttacc ttatttgcct tatttattac aagatttttg
    21361 ggaattagga agttcaccag aacaaatgtt acaattattt agaaagcata taccttttaa
    21421 tgaggataca aaagttttgg atttagcttg tggaaaaggt gctgtatctg tgaagcttgc
    21481 aaaagagttg aatatacata tcaaaggtat tgatttgata cctgaattta ttgattatgc
    21541 gagaagaaag gctattgaat ataaggttga tgctttgtgt gattttgaaa tgaatgatgc
    21601 taatagttct gtaaaaattg agcacgatta tgattgtgtg atttttggag ctgtagggga
    21661 tattttaggt aattataaag aaactataag taagctatta cctacaataa aaagtaaggg
    21721 gttcatttta attgatgatg catatgtagt agataaatct acaaatgaac agcttaattt
    21781 tgagagggtg tatcccactt acaatgagtg gtgtatattg ttcaaagaat taggtctgaa
    21841 actaattgaa tgtataccat gtttagaact tgaaaatgat gttgaagagg aaatgaactg
    21901 gattataact cgtgcaaatg agctaattaa aaaatatcct tctcaaaaag atatgtttga
    21961 acaatatgtt attagccaaa aaaatgaata tactgattta cagcaggacc ttgttggagc
    22021 aacttggatt ttacaaaaag aataagataa atattagact agataatcaa tgttgtagtg
    22081 aattatccca tgtctagtga atataaataa cataaaaaac cgtcaagatg aatagtttat
    22141 tcgtgcttga cggtttttag tatttgttga agtaaaattt tatttcttta gtatatcact
    22201 tttagtcaat ccatttgatt tagcttgagt attccattga tgattcccca taagtttata
    22261 taggaatcta gggaagttag gtgaaataaa aatagtactt ttgttggaat catctatatg
    22321 tatattatca ctaagtatat tttttgaaag ttcttttaat gcaattccta aatctttttt
    22381 aggtccttta cccaaaggta cggattctag tgaaccaaac atctccccag ctccaattcc
    22441 aataccttga acccatgtaa agttgatttt tttgcaccaa tgatctatca tttgaattgc
    22501 caaatgatta tgttcacctt cattgaatcc acagttaact attgcataca ctggaatagg
    22561 ttttttattt tgtgttttta aaaatttttc acatttctct aaaaaatgaa gtaaatgaga
    22621 tggaatacca tctacataaa gaggaaatgc tattattaat ctatcacaat taagtatggc
    22681 attaagagcg tcaggatact tagatgtgct atctacttta aatgtaaaaa ctttattatc
    22741 attttgaata agttgtttta attcagataa aaaatactgt gaattatttt tatttacttt
    22801 tggactacca tttatcatta ctatattcat atggattcac ctcttatatc ctgtatattt
    22861 tcatagaaac aaacagagtg ttcttttata ttgaaattta tagcatttcc atttactaat
    22921 ttcgtagcag tttctttttc agcttctgta atacaatctc catagaatat agcttttaaa
    22981 tttatctgtt tatcatatct gcttttatga cgcatcatat tatcttttat tacaaagtat
    23041 ggaagaatat aattaatgct tttatcaagt acgtttttga caaaagggct aaaccctccg
    23101 taacagcatc tgcttattat aataattcca tcggattcat ttataagttt acccatgttg
    23161 ctgtaataat cttttacaac acattcagaa ggagttttaa tccagcaacc aaaacgacca
    23221 atacatttgt ggatttcttt tgtgtttgga agtattttta tattgtcatc aagcttgggt
    23281 aataactttt ctaattcttt gtcagttaaa tcatgtatta aaagcttcat aaagtccatc
    23341 tccttttatt atgtatgttt atttctaaaa attatatctt atagattttt cagtaaatct
    23401 ttacaccaat taataacaaa attataatag tcaactccat aaatcattgt ggcatacata
    23461 tatgtatatt ggtcaataca atgattttct tctacatcaa ttttttgttt acttaattta
    23521 tttagaagta attctacttc agttattaac atttttaagt ttgtttcaat tatttctttg
    23581 ggtagatact tgtaaaagaa tatattaaca aggtggtctt gctttgtttt agaaaaattt
    23641 ataggtttct ttaaccattc gagaaatact tctttaccag tattagttat ggaatatagt
    23701 ttttttaatt tgctaccatc tataacttcg tgatagtgta tatatccttt tgtttctaat
    23761 cttttaagtg caggatagat acttccaaag ctggcgtcaa aaaagtacga ggtactttct
    23821 gacattattt gttttaagtc gtatccactt aattcttttt ccattaaaaa tcctaaaata
    23881 atgtattcta acatattacc tcctggtatc aatcagatat atatcgattc gatatattta
    23941 ttattacaga taataaatat tacgtcaaga tgctttttaa aataagctaa aaagaattag
    24001 gaattattga taaatatgca aaaaaattaa tataaaaggt aattaaatat caatgaagat
    24061 ttaaaaatag ttaaattaaa gtaagagtct aatatataaa atttatagta actttatggt
    24121 ttaaatataa acttgtgtgc tattgacaaa gtataaaatt agcagtaaaa taattgcatg
    24181 agcaaataga ttattgcgaa cgcaaaaaaa tgaggacaat agatattaaa ggagagaata
    24241 tgagagagct attaaaatgg gtttccatta taaatagata caatacaaat tatattgaca
    24301 ggaaattggc ggatattgga atcaataata gccaatattt ttatgtatta cacatatgta
    24361 ataatccagg tattacacag gacactatat ttgagaaaat tcttgtgaat cctagtaata
    24421 taacgagagc tttggcaaat ttagaaaaag aaggctttat aacaagagaa ccaggtgtaa
    24481 aggataaaag aacatggcat ttatatccta cagaaaaatc tttagaatgt tatgatgaaa
    24541 tactaaaaat aacaaatggg tatgttgagg agttgttgag ttcatttgag aaagaagagc
    24601 aagagttgtt tatgtcaatg ttaaagaaag ttgcattttt agctattgat atgaatgaag
    24661 aagcaaaatt ggaggcgaag gaaaatggaa gaaaaatata aggagccatt ggaatatgaa
    24721 aaggtttcaa agttattaac taagtacgca attcctagta ttatagcaat gttagtaagt
    24781 gctttatata acattgttga ccaaatattt attgggcaag gtgttggtgt attgggtaat
    24841 gctgctacaa atgtcacttt tccactaaca acaatatgta ctgcaattgc attattatta
    24901 ggaattggag gagcgtctaa gtgttcattg gaattaggtg ctaaaaattc agaaaaagct
    24961 acaaaagcag caggaaattc tatatgcttg atggctgttt ttggaataag tttatttata
    25021 gtagtatcaa tatttttaac accactatta aaattctttg gctctacatc agaaatacta
    25081 ccttatgcac acacatatac aaaaattaca tcaattggat taccatttct tataatgtcc
    25141 actggaatga gtaaattgat acttgcagat gggagaccaa aagcttctat gttttgtatg
    25201 ttaataggag cagttattaa tacaattttg aatccattat tcatttttgt ttttaatatg
    25261 ggaattgctg ggtctgcttt agcaactgtt attgggcaac ttatatcttt tggaataagt
    25321 gttcattata taaagaattt tcaacatatt aaattacata agaaaagttt taaattagat
    25381 agtataattt ataaacatat atttgcgcta ggttcaagct catgttttaa tcaattagca
    25441 atgactgtaa cacagatagt tatgaataat acattggcat attatggggc taggtcagtt
    25501 tatggaagtg agattccact tgcttgtgtc ggtatcatta ttaaagtaaa tatgattttt
    25561 atatctataa ttattggtat atcacaaggt atgcaaccaa ttatagggta taattatggg
    25621 gctgaaaagt ataatcgtgt aaaagaagca tataagtttg cagtgggaag tgcaactatt
    25681 atatctgtta ttgcattctt atgtttccaa ttcttcccaa gacaaattac gtctatattt
    25741 ggtaacggaa atgagactta ttttatattt gcagaacatt attttagaac tttcttgttc
    25801 ttaacattta taaatggtgt tcaaatagta tcatcaactt tctttacatc aattgggaaa
    25861 tcagtgttgg gactttttac ttctttgact cgtcaaattt tatttttaat tccattgata
    25921 gtaattttac caatgtttat gggaattgat ggagtaatgt ttgcaggacc aatagcagat
    25981 gcagcagcgg caatggtatg tatatacttt gcagttcatg aaatgaaatc cttgactata
    26041 aagcaaaata atttgatgag taaccataat aagattgcag aggtataaga caatatttaa
    26101 gaagtataga aaattaattt aagaaatata ataaactaat ttaggaagtg tagaaaatta
    26161 atttaaagaa gtataataaa ctaatttagg aagtgtagaa aattaattta aagaagtata
    26221 ataaactaat ttagg
//
LOCUS       DAMJWO010000060        26074 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.061, whole genome shotgun sequence.
ACCESSION   DAMJWO010000060 DAMJWO010000000
VERSION     DAMJWO010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26074
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.061"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            113..667
                     /gene="tcdR"
                     /locus_tag="PC366_002515"
     CDS             113..667
                     /gene="tcdR"
                     /locus_tag="PC366_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin sigma factor TcdR"
                     /protein_id="HDF2578016.1"
                     /translation="MQKSFYELIVLARNNSVDDLQEILFMFKPLVKKLSRVLHYEEGE
                     TDLIIFFIELIKNIKLSSFSEKSDAIIVKYIHKSLLNKTFELSRRYSKMKFNFVEFDE
                     NILNMKNNYQSKSVFEEDICFFEYILKELSGIQRKVIFYKYLKGYSDREISVKLKISR
                     QAVNKAKNRAFKKIKKDYENYFNL"
     gene            998..8098
                     /gene="tcdB"
                     /locus_tag="PC366_002516"
                     /gene_synonym="toxB"
     CDS             998..8098
                     /gene="tcdB"
                     /locus_tag="PC366_002516"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
                     /protein_id="HDF2578017.1"
                     /translation="MSLVNRKQLEKMANVRFRVQEDEYVAILDALEEYHNMSENTVVE
                     KYLKLKDINSLTDIYIDTYKKSGRNKALKKFKEYLVTEVLELKNNNLTPVEKNLHFVW
                     IGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTIVESATNDTLESFREN
                     LNDPRFDYNKFYRKRMEIIYDKQKNFINYYKTQREENPDLIIDDIVKIYLSNEYSKDI
                     DELNSYIEESLNKVTENSGNDVRNFEEFKGGESFKLYEQELVERWNLAAASDILRISA
                     LKEVGGVYLDVDMLPGIQPDLFESIEKPSSVTVDFWEMVKLEAIMKYKEYIPGYTSEH
                     FDMLDEEVQSSFESVLASKSDKSEIFSSLGDMEASPLEVKIAFNSKGIINQGLISVKD
                     SYCSNLIVKQIENRYKILNNSLNPAISEDNDFNTTTNAFIDSIMAEANADNGRFMMEL
                     GKYLRVGFFPDVKTTINLSGPEAYAAAYQDLLMFKEGSMNIHLIEADLRNFEISKTNI
                     SQSTEQEMASLWSFDDARAKAQFEEYKKNYFEGSLGEDDNLDFSQNTVVDKEYLLEKI
                     SSLARSSERGYIHYIVQLQGDKISYEAACNLFAKTPYDSVLFQKNIEDSEIAYYYNPG
                     DGEIQEIDKYKIPSIISDRPKIKLTFIGHGKDEFNTDIFAGLDVDSLSTEIETAIDLA
                     KEDISPKSIEINLLGCNMFSYSVNVEETYPGKLLLRVKDKVSELMPSISQDSIIVSAN
                     QYEVRINSEGRRELLDHSGEWINKEESIIKDISSKEYISFNPKENKIIVKSKNLPELS
                     TLLQEIRNNSNSSDIELEEKVMLAECEINVISNIDTQVVEGRIEEAKSLTSDSINYIK
                     NEFKLIESISDALYDLKQQNELEESHFISFEDILETDEGFSIRFIDKETGESIFVETE
                     KAIFSEYANHITEEISKIKGTIFDTVNGKLVKKVNLDATHEVNTLNAAFFIQSLIEYN
                     SSKESLSNLSVAMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLP
                     VIATIIDGVSLGAAIKELSETSDPLLRQEIEAKIGIMAVNLTAATTAIITSSLGIASG
                     FSILLVPLAGISAGIPSLVNNELILRDKATKVVDYFSHISLAESEGAFTSLDDKIMMP
                     QDDLVISEIDFNNNSITLGKCEIWRMEGGSGHTVTDDIDHFFSAPSITYREPHLSIYD
                     VLEVQKEELDLSKDLMVLPNAPNRVFAWETGWTPGLRSLENDGTKLLDRIRDNYEGEF
                     YWRYFAFIADALITTLKPRYEDTNIRINLDSNTRSFIVPVITTEYIREKLSYSFYGSG
                     GTYALSLSQYNMNINIELNENDTWVIDVDNVVRDVTIESDKIKKGDLIENILSKLSIE
                     DNKIILDNHEINFSGTLNGGNGFVSLTFSILEGINAVIEVDLLSKSYKVLISGELKTL
                     MANSNSVQQKIDYIGLNSELQKNIPYSFMDDKGKENGFINCSTKEGLFVSELSDVVLI
                     SKVYMDNSKPLFGYCSNDLKDVKVITKDDVIILTGYYLKDDIKISLSFTIQDENTIKL
                     NGVYLDENGVAEILKFMNKKGSTNTSDSLMSFLESMNIKSIFINSLQSNTKLILDTNF
                     IISGTTSIGQFEFICDKDNNIQPYFIKFNTLETKYTLYVGNRQNMIVEPNYDLDDSGD
                     ISSTVINFSQKYLYGIDSCVNKVIISPNIYTDEINITPIYEANNTYPEVIVLDTNYIS
                     EKINININDLSIRYVWSNDGSDFILMSTDEENKVSQVKIRFTNVFKGNTISDKISFNF
                     SDKQDVSINKVISTFTPSYYVEGLLNYDLGLISLYNEKFYINNFGMMVSGLVYINDSL
                     YYFKPPIKNLITGFTTIGDDKYYFNPDNGGAASVGETIIDGKNYYFSQNGVLQTGVFS
                     TEDGFKYFAPADTLDENLEGEAIDFTGKLTIDENVYYFGDNYRAAIEWQTLDDEVYYF
                     STDTGRAFKGLNQIGDDKFYFNSDGIMQKGFVNINDKTFYFDDSGVMKSGYTEIDGKY
                     FYFAENGEMQIGVFNTADGFKYFAHHDEDLGNEEGEALSYSGILNFNNKIYYFDDSFT
                     AVVGWKDLEDGSKYYFDEDTAEAYIGISIINDGKYYFNDSGIMQIGFVTINNEVFYFS
                     DSGIVESGMQNIDDNYFYIDENGLVQIGVFDTSDGYKYFAPANTVNDNIYGQAVEYSG
                     LVRVGEDVYYFGETYTIETGWIYDMENESDKYYFDPETKKAYKGINVIDDIKYYFDEN
                     GIMRTGLITFEDNHYYFNEDGIMQYGYLNIEDKTFYFSEDGIMQIGVFNTPDGFKYFA
                     HQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVI
                     SE"
     gene            8220..8720
                     /gene="tcdE"
                     /locus_tag="PC366_002517"
     CDS             8220..8720
                     /gene="tcdE"
                     /locus_tag="PC366_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HDF2578018.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAVLLDAMTDEM
                     NAKDEK"
     gene            8799..8960
                     /locus_tag="PC366_002518"
     CDS             8799..8960
                     /locus_tag="PC366_002518"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578019.1"
                     /translation="MKLIMKTREQMPRDTQVLNTYNFEASVHYYMDDKVVYQTLVHKD
                     GAWSVGKIY"
     gene            9049..9231
                     /locus_tag="PC366_002519"
     CDS             9049..9231
                     /locus_tag="PC366_002519"
                     /inference="COORDINATES: protein motif:HMM:NF022413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578020.1"
                     /translation="MRDEGQNDRENKYQTLINDLIDSLKVIGKIYKEIKTLKKYKICL
                     QITIRQSPYLIEESIN"
     gene            9448..17580
                     /gene="tcdA"
                     /locus_tag="PC366_002520"
                     /gene_synonym="toxA"
     CDS             9448..17580
                     /gene="tcdA"
                     /locus_tag="PC366_002520"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021394011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HDF2578021.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKNSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     LLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTIPRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKDSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPG
                     LASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKEYGPLKTEDDKIL
                     VPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPYISSHIPSLSV
                     YSAIGIKTENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENNGTKLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNTKIKLDKDTRNFIMPTITTDEIRNKLSYSFDGA
                     GGTYSLLLSSYPISMNINLSKDDLWIFNIDNEVREISIENGTIKKGNLIEDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNGSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKV
                     NGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLNNISFWKLFGFENINFVIDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLGYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEDSKLVKGLININNSLFY
                     FDPIESNLVTGWQTINGKKYYFDINTGAASTSYKIINGKHFYFNNNGVMQLGVFKGPD
                     GFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNDSKAVTGWRIINNEKYYFNP
                     NNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKH
                     FYFDSDCVVKIGVFSGSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNS
                     KAVTGWQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAEAATGWQTIDGKKYYF
                     NTNTSIASTGYTIINGKYFYFNTDGIMQIGVFKVPNGFEYFAPANTHNNNIEGQAILY
                     QNKFLTLNGKKYYFGSDSKAITGWQTIDGKKYYFNPNNAIAATHLCTINNDKYYFSYD
                     GILQNGYITIERNNFYFDANNESKMVTGVFKGPNGFEYFAPANTHNNNIEGQAIVYQN
                     KFLTLNGKKYYFDNDSKAVTGWQTIDSKKYYFNLNTAVAVTGWQTIDGEKYYFNLNTA
                     EAATGWQTIDGKRYYFNTNTYIASTGYTIINGKHFYFNTDGIMQIGVFKGPDGFEYFA
                     PANTHNNNIEGQAILYQNKFLTLNGKKYYFGSDSKAVTGLRTIDGKKYYFNTNTAVAV
                     TGWQTINGKKYYFNTNTYIASTGYTIISGKHFYFNTDGIMQIGVFKGPDGFEYFAPAN
                     TDANNIEGQAIRYQNRFLYLHDNIYYFGNDSKAATGWATIDGNRYYFEPNTAMGANGY
                     KTIDNKNFYFRNGLPQIGVFKGPNGFEYFAPANTDANNIDGQAIRYQNRFLHLLGKIY
                     YFGNNSKAVTGWQTINSKVYYFMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIYG"
     gene            complement(17915..18475)
                     /locus_tag="PC366_002521"
     CDS             complement(17915..18475)
                     /locus_tag="PC366_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin regulator"
                     /protein_id="HDF2578022.1"
                     /translation="MFFGNISSPACSEDHEEVISNQTSVIDSQKTEIETLNSKLSDAE
                     PWFKMKDDEKKAIEAENQRKAEEAKKAEEQRKKEEEEKKGYDTGITYDQLARTPDDYK
                     YKKVKFEGKVIQVIEDGDEVQIRLAVSGNYDKVVLCSYKKSITPSRVLEDDYITIRGI
                     SAGTITYESTMGGKITIPGIAVEKIN"
     gene            19012..19257
                     /locus_tag="PC366_002522"
     CDS             19012..19257
                     /locus_tag="PC366_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pathogenicity locus"
                     /protein_id="HDF2578023.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLM
                     RGQHIDRCQLYVYRCAVYFASTENPEPEKLKWWYWKD"
     gene            complement(19474..19743)
                     /locus_tag="PC366_002523"
     CDS             complement(19474..19743)
                     /locus_tag="PC366_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF2578024.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNKGKDQGFDPMVNIGQCRKWLEETVSN"
     gene            complement(19955..20257)
                     /locus_tag="PC366_002524"
     CDS             complement(19955..20257)
                     /locus_tag="PC366_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578025.1"
                     /translation="MKYSKGFKLIYSLVEYSKKFKVIYSVMKYSKGFKLIYSLVEYSK
                     RFKLIYDVMKYSKEFKLIYSLVEYSKRFKVIYSVMKYSKRFKAIYNAVKYIQGDLK"
     gene            complement(20777..21514)
                     /locus_tag="PC366_002525"
     CDS             complement(20777..21514)
                     /locus_tag="PC366_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2578026.1"
                     /translation="MLRKSVLGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSILTAITQVFFVIFYIVAGNMFGFSGSVPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVAKPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     TICVAFITTIVFSEIANRNFRKNDVIS"
     gene            complement(21526..22287)
                     /locus_tag="PC366_002526"
     CDS             complement(21526..22287)
                     /locus_tag="PC366_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2578027.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFVAVEIMWCIVNSNRAITRNPD
                     MLGGFEYSYMLMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVTSLNSIYL
                     SKFLCSAILVSIPILMQVLSIVLFGHFRGVIESISVSLLLKYTLGTILVSIAIIALHL
                     WIATVIPNQMIAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDMNFSITILVFLIGMLIYYIGRNHLLKKEV"
     gene            complement(22287..23210)
                     /locus_tag="PC366_002527"
     CDS             complement(22287..23210)
                     /locus_tag="PC366_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578028.1"
                     /translation="MKHMEMIIRTQRLSKEYNKIFRVKDIDLRVPQGAVYGFLGPNGA
                     GKSTTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENM
                     TIMQRLLDLPKKNVNEALKIVRLENQKNKKVNQYSLGMKQRLGIAMAIMKFPKLLILD
                     EPTNGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQD
                     SIKELHNRGQSQIAIKAKNVVSAQKLLNTKGYMSLIQNGYLTIENLKDSDVAKINGML
                     VHSNIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            23372..24079
                     /locus_tag="PC366_002528"
     CDS             23372..24079
                     /locus_tag="PC366_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2578029.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAV
                     RVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
                     LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPST
                     PKHLITVRGLGYKLMIN"
     gene            24124..25530
                     /locus_tag="PC366_002529"
     CDS             24124..25530
                     /locus_tag="PC366_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2578030.1"
                     /translation="MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSD
                     NLDTSDSREIKSNLIMIEDNLILKDGKFILDDSSKEVLHKNKVWAMLIDNNGDRIWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTIKE
                     IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGIL
                     SDISKSINTVSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSS
                     LSNREQEQVSIICNQGVKIRELVNDLNLVSKLEYNMQALNCDKIRVSAFLRELISEFI
                     NNNLDNDFYVELDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLD
                     FCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIVAGIINAHRGKLDI
                     MSIDSQGLKTILKLPLIK"
BASE COUNT        10198 a         3056 c         3940 g         8880 t
ORIGIN      
        1 atataaaatt taatttattt gccgattata taattataat gactgattta attccaatgt
       61 tgtcaaaatt tttaaataaa tcatcattat aaatataaga gaggatgatt ttatgcaaaa
      121 gtctttttat gaattaattg ttttagcaag aaataactca gtagatgatt tgcaagaaat
      181 tttatttatg tttaagccat tagtaaaaaa acttagtaga gttttacatt atgaagaggg
      241 agaaacagat ttaataatat tttttattga attaataaaa aatattaaat taagtagctt
      301 ttcagaaaaa agcgatgcta ttatagtcaa atatattcat aaatcattac tgaataagac
      361 ttttgagttg tctagaagat attctaaaat gaagtttaat tttgtagaat ttgatgaaaa
      421 tatcttaaat atgaaaaata attatcaaag taagtctgtt tttgaggaag atatttgttt
      481 tttcgaatat attttgaaag aattatctgg tattcaaaga aaagttattt tttataaata
      541 tttaaaagga tattctgata gagaaatatc agtgaaatta aaaatatcta gacaagctgt
      601 taataaggct aaaaatagag catttaaaaa aataaaaaaa gactatgaaa attattttaa
      661 cttgtaatta atgaatttaa agaaatattt acaatagaaa tcaaatttta gaattaactt
      721 tattgtaaaa tcaataactt aatctaagaa tatcttaatt tttatatttt atatagaaca
      781 aagtttacat atttatttca gacaacgtct ttattcaatc gaagagcaaa ttaatcaact
      841 gagtgtcttc aatttaaaat gttaggaagt gaatgtatat gaaaacctaa gtagatatta
      901 gtatatttta taaatagaaa ggaggatata taaaagagtt ttagcattta gatgtaaaaa
      961 tattcaataa aaatattata gtaaaggaga aaattttatg agtttagtta atagaaaaca
     1021 gttagaaaaa atggcaaatg taagatttcg tgttcaggaa gatgaatatg tagcaatatt
     1081 ggatgcttta gaagaatatc ataatatgtc agagaatact gtagtcgaaa aatatttaaa
     1141 attaaaagat ataaatagtt taacagatat ttatatagat acatataaaa agtctggtag
     1201 aaataaagcc ttaaaaaaat ttaaggaata cctagttaca gaagtattag agctaaagaa
     1261 taataattta actccagttg agaaaaattt acattttgtt tggattggag gtcaaataaa
     1321 tgacactgct attaattata taaatcaatg gaaagatgta aatagtgatt ataatgttaa
     1381 tgttttttat gatagtaatg catttttgat aaacacattg aaaaaaacta tagtagaatc
     1441 agcaacaaat gatacacttg aatcatttag agaaaactta aatgacccta gatttgacta
     1501 taataaattt tacagaaaac gtatggagat aatctatgat aagcagaaaa atttcataaa
     1561 ttactataaa actcaaagag aagaaaatcc tgaccttata attgatgata ttgtaaagat
     1621 atatctttca aacgagtatt caaaggatat agatgaactt aattcctata ttgaagagtc
     1681 attaaataaa gttacagaaa atagtgggaa tgatgttaga aactttgaag aatttaaagg
     1741 tggagagtca ttcaaattat atgaacaaga gttggtagaa agatggaatt tggcagctgc
     1801 ttctgacata ttaagaatat ctgccttaaa agaagttggt ggtgtatatt tagatgttga
     1861 tatgttacca ggaatacaac cagacctatt tgagtctata gagaaaccta gttcagtaac
     1921 agtggatttt tgggaaatgg taaaattaga agctataatg aaatacaaag aatacatacc
     1981 aggatatact tcagagcatt ttgatatgtt ggatgaagaa gttcaaagta gttttgaatc
     2041 tgttctagct tctaagtcag ataagtcaga aatattctca tcacttggcg atatggaggc
     2101 atcaccacta gaagttaaaa ttgcatttaa tagtaaaggt attataaatc aaggactaat
     2161 ttctgtgaaa gactcatatt gtagcaattt aatagtaaaa caaatcgaga acagatataa
     2221 gatattgaat aatagtttaa atccagctat tagcgaggat aacgatttca atactacaac
     2281 gaatgctttt attgatagta taatggctga agctaatgca gataatggta gatttatgat
     2341 ggaactagga aagtatttaa gagttggttt cttcccagat gttaaaacta ctattaactt
     2401 aagtggccct gaagcatatg cggcagctta tcaagattta ttaatgttta aagaaggtag
     2461 tatgaatatc catttgatag aagctgactt aagaaacttt gaaatctcta aaactaatat
     2521 ttctcaatca actgaacaag aaatggctag cttatggtca tttgacgatg caagagctaa
     2581 agctcaattt gaagaataca aaaaaaatta ctttgaaggt tctcttggag aagatgacaa
     2641 tcttgacttt tctcaaaata cagtagttga caaggagtat cttttagaaa aaatatcttc
     2701 attagcaaga agttcagaga gaggatatat acactatatt gttcagttac aaggagataa
     2761 aattagttat gaagcagcat gtaacttatt tgcaaagact ccttatgata gtgtactgtt
     2821 tcagaaaaat atagaagatt cagaaattgc atattattat aatcctggag atggtgaaat
     2881 acaagaaata gacaagtata aaattccaag tataatttct gatagaccta agattaaatt
     2941 aacatttatt ggtcatggta aagatgaatt taatactgat atatttgcag gtcttgatgt
     3001 agattcatta tccacagaaa tagaaacagc aatagattta gctaaagagg atatttctcc
     3061 taagtcaata gaaataaact tactgggatg taacatgttt agctattctg taaatgtaga
     3121 ggagacttat cctgggaaat tattacttag agttaaagat aaagtatcag aattaatgcc
     3181 atctataagt caagactcta ttatagtaag tgcaaatcaa tatgaagtta gaataaatag
     3241 tgaaggaaga agagaattat tggatcattc tggtgaatgg ataaataaag aagaaagtat
     3301 tataaaggat atttcatcaa aagaatatat atcatttaat cctaaagaaa ataaaattat
     3361 agtaaaatct aaaaatttac ctgaattatc tacattatta caagaaatta gaaacaattc
     3421 taattcaagt gatattgaac tagaagaaaa agtaatgtta gcagaatgtg agataaatgt
     3481 tatttcaaat atagatacac aagtggtaga aggaaggatt gaagaagcta aaagcttaac
     3541 ttctgactct attaattata taaagaatga atttaaacta atagaatcta tttctgatgc
     3601 actatacgat ttaaaacaac agaatgaatt agaagagtct cattttatat cttttgagga
     3661 tatattggag actgatgaag gctttagtat aagatttatt gataaagaaa ctggagaatc
     3721 tatatttgta gaaactgaaa aggcaatatt ctctgaatat gctaatcata taactgaaga
     3781 gatttctaag ataaaaggta ctatatttga tactgtaaat ggtaagttag taaaaaaagt
     3841 aaatttagat gctacacatg aagtgaatac tttaaatgct gcatttttta tacaatcatt
     3901 aatagaatat aatagttcta aagaatctct tagtaattta agtgtagcaa tgaaagttca
     3961 agtttatgct caattattta gtactggttt aaatactatt acagatgcag ccaaagttgt
     4021 tgaattagta tcaactgcat tagatgaaac tatagattta cttcctacat tatctgaagg
     4081 attacctgta attgcaacta tcatagatgg tgtaagttta ggtgcagcaa tcaaagagct
     4141 aagtgaaaca agtgacccat tattaagaca agaaatagaa gctaagatag gtataatggc
     4201 agtaaattta acagcagcta caactgcaat cattacttca tctttaggaa tagctagtgg
     4261 atttagtata cttttagttc ctttagcagg aatttcagca ggtataccaa gtttagtaaa
     4321 caatgagctt atcctaagag ataaagcaac aaaagttgta gattatttta gtcatatatc
     4381 attagctgag tctgaaggag catttacttc attagatgat aaaataatga tgccacaaga
     4441 tgatttagta atatctgaga tagactttaa taacaattca ataactttag gtaaatgtga
     4501 aatctggaga atggaaggtg gctcaggtca tactgtaact gatgatatag atcacttctt
     4561 ttcagcacca tcaataacat atagagagcc acacttatct atatatgacg tattggaagt
     4621 acaaaaagaa gaacttgatt tgtcaaaaga tttaatggta ttacctaatg ctccaaatag
     4681 agtatttgct tgggaaacag gatggacacc aggtttaaga agcttagaaa atgatggcac
     4741 aaaactgtta gaccgtataa gagataacta tgaaggtgag ttttattgga gatattttgc
     4801 ttttatagct gatgctttaa taacaacatt aaaaccaaga tatgaagata ctaatataag
     4861 aataaattta gatagtaata ctagaagctt tatagtccca gtgataacta cagaatatat
     4921 aagagagaaa ttatcatatt ctttttatgg ttctggagga acttatgcat tatctctttc
     4981 tcaatacaat atgaatataa acatagaatt aaatgaaaat gatacttggg ttatagatgt
     5041 cgacaatgtc gtaagagatg tcactataga atctgataaa attaaaaaag gagatttaat
     5101 agagaatatt ttatctaaat taagtattga agacaataaa attattttag ataatcatga
     5161 aattaatttc tctggaacat taaatggagg taatggattt gtatctttaa cattctcaat
     5221 cttagaagga ataaatgcag ttatagaagt tgatttatta tctaaatcat ataaagttct
     5281 tatttctggt gaactaaaaa cattgatggc aaattcaaat tctgttcaac agaaaataga
     5341 ttatatagga ttgaacagcg aattacaaaa aaatatacct tatagtttta tggatgataa
     5401 aggaaaagaa aatggattta ttaattgttc tacaaaagaa ggtttatttg tatctgaatt
     5461 atctgatgta gttcttataa gtaaagttta tatggacaat agtaaacctc tatttggata
     5521 ttgtagtaat gatttgaaag atgttaaagt cataactaaa gatgacgtta ttatattaac
     5581 aggatattat ttaaaagatg atataaaaat ctctctttct tttactatac aagatgaaaa
     5641 tactataaaa ttaaatggag tatatttaga tgaaaatgga gtagctgaaa tattgaaatt
     5701 tatgaataaa aaaggtagta caaatacttc agattcttta atgagctttt tagaaagtat
     5761 gaatataaaa agtattttca taaattcctt acaatctaat actaagctta tattagatac
     5821 taattttata ataagtggta ctacttctat tggtcaattt gagtttattt gtgataaaga
     5881 taataatata caaccatatt tcattaagtt taatacacta gaaactaaat atactctata
     5941 tgtaggtaat agacaaaata tgatagtaga accaaattat gatttagatg attctggaga
     6001 tatatcttca actgtcatta atttttctca gaaatacctt tatggaatag acagttgtgt
     6061 taataaagtt ataatttcgc caaatatata tacagatgaa ataaacataa cacctatata
     6121 tgaagcaaat aatacttatc cagaagtgat tgtattagat acaaattata taagtgaaaa
     6181 aatcaatatt aatatcaatg atttatctat acgatatgta tggagtaatg atggaagtga
     6241 ttttattctt atgtcaactg atgaagagaa caaggtatca caagttaaaa taagatttac
     6301 taatgttttt aaaggtaata ctatatcaga taagatatct tttaatttta gtgataagca
     6361 agatgtatct ataaataaag ttatttcaac atttacacct tcatattatg tggaaggatt
     6421 acttaattat gatttaggtc tgatttcttt atacaatgag aaattttata ttaataactt
     6481 tggaatgatg gtgtctggat tagtatatat taatgattca ttatattatt tcaagccacc
     6541 aataaagaac ttgataactg gatttacaac tataggtgat gataaatact actttaatcc
     6601 agataatggt ggagctgctt cagtcggaga aacaataatt gatggcaaaa actactactt
     6661 cagccaaaat ggagtgttac aaacaggtgt atttagtaca gaagatggat ttaaatattt
     6721 tgctccagca gatacacttg atgaaaatct agagggggaa gcaattgatt ttactggcaa
     6781 actaactatt gatgaaaatg tttattattt tggagataat tatagagcag ctatagaatg
     6841 gcaaacatta gatgatgaag tgtactattt tagtacagat acaggtagag cttttaaagg
     6901 gctaaatcaa ataggtgatg ataaattcta tttcaactct gatggtatta tgcaaaaagg
     6961 atttgttaat ataaatgata agacattcta ttttgatgat tctggtgtga tgaagtcagg
     7021 atatactgaa atagatggaa aatattttta ctttgctgag aatggagaaa tgcaaatagg
     7081 agtatttaat acagcagatg gatttaaata ttttgctcat catgatgaag atttaggaaa
     7141 tgaagaaggt gaagcacttt catattctgg tatacttaat tttaacaata agatttatta
     7201 ttttgatgat tcatttacag cagtagttgg atggaaggat ttagaagatg gttcaaaata
     7261 ttactttgat gaagatacag cagaagcata tataggtatc tcaataatta atgatggtaa
     7321 atattatttt aatgattctg gaatcatgca aattggattt gtcacaataa ataatgaagt
     7381 attttatttc tctgattctg gaatagtaga atctggaatg caaaatatag atgataatta
     7441 tttctatata gacgaaaatg gtctagttca aattggtgta tttgacactt cagatggata
     7501 taaatacttt gcaccagcta atactgtaaa tgataatatc tatggacaag cagttgaata
     7561 tagtggttta gttagagttg gtgaagatgt atattatttt ggagaaacat atacaattga
     7621 gactggttgg atatatgata tggaaaatga aagtgataaa tattatttcg atccagaaac
     7681 taaaaaagca tataaaggta ttaatgtaat tgatgatata aaatactatt ttgatgagaa
     7741 tggaataatg agaacaggtc ttataacatt tgaagataat cattactatt ttaatgaaga
     7801 tggtattatg caatatggtt atctaaatat agaagataag acgttctact ttagtgaaga
     7861 tggtattatg cagattggag tatttaatac accagatgga tttaaatatt ttgcacatca
     7921 aaatacttta gatgagaatt ttgagggaga atcaataaac tatactggtt ggttagattt
     7981 agatgaaaag agatattatt ttacagatga atatattgca gcaactggtt cagttattat
     8041 tgatggtgag gagtattatt ttgatcctga tacagctcaa ttagtgatta gtgaatagat
     8101 aaaaatacgt taaatatatc ctcttatact taaatatata aaaataaaca aaatgataca
     8161 ctacataaag tgttctatct aatatgaaga tttaccaata aaaaggtgaa ctatgatgaa
     8221 tgcacagtag ttcacctttt tatatttcta atggtaacaa aatatttttt tatataaacc
     8281 taggaggcgt tatgaatatg acaatatctt ttttatcaga gcatatattt ataaagttag
     8341 taattttaac tatatcattt gatacattat taggatgttt aagtgcaata aaaagtcgta
     8401 aatttaattc tagttttgga atagatggag gaatcagaaa agtagcaatg atagcatgta
     8461 tatttttttt atcagtagtt gacattctta caaagtttaa ctttttattt atgttaccac
     8521 aagattgtat caatttttta agactaaaac atcttggaat atctgaattt ttctctattt
     8581 tatttatttt atatgaaagt gtaagcatat taaaaaatat gtgcttatgt ggattaccag
     8641 tacctaagag attaaaggaa aaaatagcag ttttactaga tgcaatgaca gatgaaatga
     8701 atgctaagga tgaaaagtaa gtaatggtag atataataaa aatattaaca aataaaaagt
     8761 gttatccaaa taagaatagc tgaaagttat cataattcat gaaactgata atgaaaacga
     8821 gggagcagat gccaagagac acacaagtat taaatacata taatttcgaa gcaagtgttc
     8881 attactatat ggatgacaag gtagtatatc aaacattggt tcacaaagat ggtgcatggt
     8941 cagttggtaa aatctattaa gctacattag ttacagatat cacaaactat aatagttaaa
     9001 catagaaata tgtgtaaatt gtgatggaaa ttattcaaaa acacaaaaat acgtgatgaa
     9061 ggacaaaatg atagagaaaa taagtatcaa accttaataa atgatttaat tgatagttta
     9121 aaagttatag gaaaaatata taaagaaata aaaacattaa aaaaatataa gatatgttta
     9181 caaattacta tcagacaatc tccttatcta atagaagagt caattaacta attgagtatc
     9241 tttaaattga aatgttagga agtgatttaa atatgaaaac ttaaattata aaaaatcaat
     9301 attaatttat ctttaaaaaa tagaaaggag tgtataagat ttattttcaa agtttaaaaa
     9361 caagaaaatc aatttaaatt tcagaaggaa taaatgtggt tatagaagtg gatttattat
     9421 caaaaataat agtactagga ggtttttatg tctttaatat ctaaagaaga gttaataaaa
     9481 ctcgcatata gcattagacc aagagaaaat gagtataaaa ctatactaac taatttagac
     9541 gaatataata agttaactac aaacaataat gaaaataaat atttacaatt aaaaaaacta
     9601 aatgaatcaa ttgatgtttt tatgaataaa tataaaaatt caagcagaaa tagagcactc
     9661 tctaatctaa aaaaagatat attaaaagaa gtaattctta ttaaaaattc caatacaagt
     9721 cctgtagaaa aaaatttaca ttttgtatgg ataggtggag aagtcagtga tattgctctt
     9781 gaatacataa aacaatgggc tgatattaat gcagaatata atattaaact gtggtatgat
     9841 agtgaagcat tcttagtcaa tacactaaaa aaggctatag ttgaatcttc taccactgaa
     9901 gcattacagc tactagagga agagattcaa aatcctcaat ttgataatat gaaattttac
     9961 aaaaaaagga tggaatttat atatgataga caaaaaaggt ttataaatta ttataaatct
    10021 caaatcaata aacctacagt acctacaata gatgatatta taaagtctca tctagtatct
    10081 gaatataata gagatgaaac tttattagaa tcatatagaa caaattcttt gagaaaaata
    10141 aatagtaatc atgggataga tatcagggct aatagtttgt ttacagaaca agagttatta
    10201 aatatttata gtcaggagtt gttaaatcgt gggaatttag ctgcagcatc tgacatagta
    10261 agattattag ccctaaaaaa ttttggcgga gtatatttag atgttgatat gcttccaggt
    10321 attcactctg atttatttaa aacaatacct agacctagct ctattggact agaccgttgg
    10381 gaaatgataa aattagaggc tattatgaag tataaaaaat atataaataa ttatacatca
    10441 gaaaactttg ataaacttga tcaacaatta aaagataatt ttaaactcat tatagaaagt
    10501 aaaagtgaaa aatctgagat attttctaaa ttagaaaatt taaatgtatc tgatcttgaa
    10561 attaaaatag ctttcgcttt aggcagtgtt ataaatcaag ccttgatatc aaaacaaggt
    10621 tcatatctta ctaacctagt aatagaacaa gtaaaaaata gatatcaatt tttaaaccaa
    10681 caccttaacc cagccataga gtctgacaat aacttcacag atactactaa gatttttcat
    10741 gattcactat ttaattcagc taccgcagaa aactctatgt ttttaacaaa aatagcacca
    10801 tacttacaag taggttttat gccagaagct cgctccacaa taagtttaag tggtccagga
    10861 gcttatgcat cagcttacta tgatttcata aatttacaag aaaatactat agaaaaaact
    10921 ttaaaagcat cagatttaat agaatttaaa ttcccagaaa ataatctatc tcaattgaca
    10981 gaacaagaaa taaatagtct atggagcttt gatcaagcaa gtgcaaaata tcaatttgag
    11041 aaatatgtaa gagattatac tggtggatct ctttctgaag acaatggggt agactttaat
    11101 aaaaatactg ccctcgacaa aaactattta ttaaataata aaattccatc aaacaatgta
    11161 gaagaagctg gaagtaaaaa ttatgttcat tatatcatac agttacaagg agatgatata
    11221 agttatgaag caacatgcaa tttattttct aaaaatccta aaaatagtat tattatacaa
    11281 cgaaatatga atgaaagtgc aaaaagttac tttttaagtg atgatggaga atctatttta
    11341 gaattaaata aatataggat acctgaaaga ttaaaaaata aggaaaaagt aaaagtaacc
    11401 tttattggac atggtaaaga tgaattcaac acaagcgaat ttgctagatt aagtgtagat
    11461 tcactttcca atgagataag ttcattttta gataccataa aattagatat atcacctaaa
    11521 aatgtagaag taaacttgct tggatgtaat atgtttagtt atgattttaa tgttgaagaa
    11581 acttatcctg gtaagttact attaagtatt atggacaaaa ttacttccac tttacctgat
    11641 gtaaataaag attctattac tataggagca aatcaatatg aagtaagaat taatagtgag
    11701 ggaagaaaag aacttctagc tcactcaggt aaatggataa ataaagagga agctattatg
    11761 agcgatttat ctagtaaaga atacattttt tttgattcca tagataataa gctaaaagca
    11821 aagtccaaga atattccagg tttagcgtca atatcagaag atataaaaac attattactt
    11881 gatgcaagtg ttagtcctga tacaaaattt attttaaata atcttaagct taatattgaa
    11941 tcttctattg gtgattacat ttattatgaa aaattagaac ctgttaaaaa tataatccac
    12001 aattctatag atgatttaat agatgagttc aatctacttg aaaatgtatc tgatgaatta
    12061 tatgaattaa aaaaattaaa taatctagat gagaagtatt taatatcttt tgaagatatc
    12121 tcaaaaaata attcaactta ttctgtaaga tttattaaca aaagtaatgg tgaatcagtt
    12181 tatgtagaga cagaaaaaga aattttttca aaatatagcg aacatattac aaaagaaata
    12241 agtactataa agaatagtat aattacagat gttaatggta atttattgga taatatacag
    12301 ttagatcata cttctcaagt taatacatta aacgcagcat tctttattca atcattaata
    12361 gattatagta gcaataaaga tgtactgaat gatttaagta cctcagttaa ggttcaactt
    12421 tatgctcaac tatttagtac aggtttaaat actatatatg actctatcca attagtaaat
    12481 ttaatatcaa atgcagtaaa tgatactata aatgtactac ctacaataac agaggggata
    12541 cctattgtat ctactatatt agacggaata aacttaggtg cagcaattaa ggaattacta
    12601 gacgaacatg acccattact aaaaaaagaa ctagaagcta aggtgggtgt tttagcaata
    12661 aatatgtcat tatctatagc tgcaacggta gcttcaattg ttggaatagg tgctgaagtt
    12721 actattttct tattacctat agctggtata tctgcgggaa taccttcatt agttaataat
    12781 gaattaatat tgcatgataa ggcaacttca gtggtaaact attttaatca tttgtctgaa
    12841 tctaaagaat atggccctct taaaacagaa gatgataaaa ttttagttcc tattgatgat
    12901 ttagtaatat cagaaataga ttttaataat aattcgataa aactaggaac atgtaatata
    12961 ttagcaatgg aggggggatc aggacacaca gtgactggta atatagatca ctttttctca
    13021 tctccatata taagctctca tattccttca ttatcagttt attctgcaat aggtataaaa
    13081 acagaaaatc tagatttttc aaaaaaaata atgatgttac caaatgctcc ttcaagagtg
    13141 ttttggtggg aaactggagc agttccaggt ttaagatcat tggaaaataa tgggactaaa
    13201 ttgcttgatt caataagaga tttataccca ggcaaatttt actggagatt ctatgccttt
    13261 ttcgattatg caataactac attaaaacca gtgtatgaag acactaatac taaaattaaa
    13321 ctagataaag atactagaaa ctttataatg ccaactataa ctactgacga aattagaaac
    13381 aaattatctt attcatttga tggagcagga ggaacttact ctttattatt atcttcatat
    13441 ccaatatcaa tgaatataaa tttatctaaa gatgatttat ggatatttaa tattgataat
    13501 gaagtaagag aaatatctat agaaaatggt actattaaaa aaggaaattt aatagaagat
    13561 gttttaagta aaattgatat aaataaaaat aaacttatta taggcaatca aacaatagat
    13621 ttttcaggtg atatagataa caaagataga tatatattct tgacttgtga gttagatgat
    13681 aaaattagtt taataataga aataaatctt gttgcaaaat cttatagttt gttattgtct
    13741 ggggataaaa attatttgat atccaattta tctaatacta ttgagaaaat caatacttta
    13801 ggcctagata gtaaaaatat agcttacaat tacactgatg aatctaataa taaatatttt
    13861 ggagctatat ctaaaacaag tcaaaaaagc ataatacatt ataaaaaaga cagtaaaaat
    13921 atattagaat tttataatgg cagtacatta gaatttaaca gtaaagactt tattgctgaa
    13981 gatataaatg tatttatgaa agatgatatt aatactataa caggaaaata ctatgttgat
    14041 aataatactg ataaaagtat agatttctct atttctttag ttagtaaaaa tcaagtaaaa
    14101 gtaaatggat tatatttaaa tgaatccgta tactcatctt accttgattt tgtgaaaaat
    14161 tcagatggac accataatac ttctaatttt atgaatttat ttttgaacaa tataagtttc
    14221 tggaaattgt ttgggtttga aaatataaat tttgtaatcg ataaatactt tacccttgtt
    14281 ggtaaaacta atcttggata tgtagaattt atttgtgaca ataataaaaa tatagatata
    14341 tattttggtg aatggaaaac atcgtcatct aaaagcacta tatttagcgg aaatggtaga
    14401 aatgttgtag tagagcctat atataatcct gatacgggtg aagatatatc tacttcacta
    14461 gatttttcct atgaacctct ctatggaata gatagatata tcaataaagt attgatagca
    14521 cctgatttat atacaagttt aataaatatt aataccaatt attattcaaa tgagtactac
    14581 cctgagatta tagttcttaa cccaaataca ttccacaaaa aagtaaatat aaatttagat
    14641 agttcttctt ttgagtataa atggtctaca gaaggaagtg actttatttt agttagatac
    14701 ttagaagaaa gtaataaaaa aatattacaa aaaataagaa tcaaaggtat cttatctaat
    14761 actcaatcat ttaataaaat gagtatagat tttaaagata ttaaaaaact atcattagga
    14821 tatataatga gtaattttaa atcatttaat tctgaaaatg aattagatag agatcattta
    14881 ggatttaaaa taatagataa taaaacttat tactatgatg aagatagtaa attagttaaa
    14941 ggattaatca atataaataa ttcattattc tattttgatc ctatagaatc taacttagta
    15001 actggatggc aaactatcaa tggtaaaaaa tattattttg atataaatac tggagcagct
    15061 tcaactagtt ataaaattat taatggtaaa cacttttatt ttaataataa tggtgtgatg
    15121 cagttaggag tatttaaagg acctgatgga tttgagtatt ttgcacctgc caatactcag
    15181 aataataaca tagaaggtca ggctatagtt tatcaaagta aattcttaac tttgaatggc
    15241 aaaaaatatt attttgataa tgactcaaaa gcagtcactg gatggaggat tattaacaat
    15301 gagaaatatt actttaatcc taataatgct attgctgcag tcggattgca agtaattgac
    15361 aataataagt attatttcaa tcctgacact gctatcatct caaaaggttg gcagactgtt
    15421 aatggtagta gatactactt tgatactgat accgctattg cctttaatgg ttataaaact
    15481 attgatggta aacactttta ttttgatagt gattgtgtag tgaaaatagg tgtgtttagt
    15541 ggctctaatg gatttgaata tttcgcacct gctaatactt ataataataa catagaaggt
    15601 caggctatag tttatcaaag taaattctta actttgaatg gtaaaaaata ttactttgat
    15661 aataactcaa aagcagttac cggatggcaa actattgata gtaaaaaata ttactttaat
    15721 actaacactg ctgaagcagc tactggatgg caaactattg atggtaaaaa gtattacttt
    15781 aatactaaca ctgctgaagc agctactgga tggcaaacta ttgatggtaa aaaatattac
    15841 tttaatacta acacttctat agcttcaact ggttatacaa ttattaatgg taaatatttt
    15901 tattttaata ctgatggtat tatgcagata ggagtgttta aagtacctaa tggatttgaa
    15961 tactttgcac ctgctaatac tcataataat aacatagaag gtcaagctat actttaccaa
    16021 aataaattct taactttgaa tggtaaaaaa tattactttg gtagtgactc aaaagcaatt
    16081 actggatggc aaaccattga tggtaaaaaa tattacttta atcctaataa tgctattgct
    16141 gcgactcatc tatgcactat aaataacgac aagtattact ttagttatga tggaattctt
    16201 caaaatggat atattactat tgaaagaaat aatttctatt ttgatgctaa taatgaatct
    16261 aaaatggtaa caggagtatt taaaggacct aatggatttg agtattttgc acctgctaat
    16321 actcataata ataacataga aggtcaggct atagtttacc agaataaatt cttaactttg
    16381 aatggcaaaa aatattattt tgataatgac tcaaaagcag ttactggatg gcaaactatt
    16441 gatagtaaaa aatattactt taatcttaac actgctgttg cagttactgg atggcaaact
    16501 attgatggtg aaaaatatta ctttaatctt aacactgctg aagcagctac tggatggcaa
    16561 actattgatg gtaaaagata ctactttaat actaacactt atatagcttc aactggttat
    16621 acgattatta atggtaaaca tttttatttt aatactgatg gtattatgca gataggagtg
    16681 tttaaaggac ctgatggatt tgaatacttt gcacctgcta atactcataa taataacata
    16741 gaaggtcaag ctatacttta ccaaaataaa ttcttaactt tgaatggtaa aaaatattac
    16801 tttggtagtg actcaaaagc agttaccgga ttgcgaacta ttgatggtaa aaaatattac
    16861 tttaatacta acactgctgt tgcagttact ggatggcaaa ctattaatgg taaaaaatac
    16921 tactttaata ctaacactta tatagcttca actggttata caattattag tggtaaacat
    16981 ttttatttta atactgatgg tattatgcag ataggagtgt ttaaaggacc tgatggattt
    17041 gaatactttg cacctgctaa tacggatgct aacaacatag aaggtcaagc tatacgttat
    17101 caaaatagat tcctatattt acatgacaat atatattact ttggcaatga ttcaaaagcg
    17161 gctactggtt gggcaactat tgatggtaat agatattact tcgagcctaa tacagctatg
    17221 ggtgcgaatg gttataaaac tattgataat aaaaattttt actttagaaa tggtttacct
    17281 cagataggag tgtttaaagg acctaatgga tttgaatact ttgcacctgc taatacggat
    17341 gctaacaata tagatggtca agctatacgt tatcaaaata gattcctaca tttacttgga
    17401 aaaatatatt actttggtaa taactcaaaa gcagttactg gatggcaaac tattaatagt
    17461 aaagtatatt actttatgcc tgatactgct atggctgcag ctggtggact tttcgagatt
    17521 gatggtgtta tatatttctt tggtgttgat ggagtaaaag cccctgggat atatggctaa
    17581 aatatatgtt tgacaaaaaa ttattcctgt gatactcaga aattattttt atataataaa
    17641 tattgagatt taattaaaag tcatgtgtta ttgtaataca tgacttttag ttaaaatttt
    17701 tctatcattt aataatctat tattcttgac tattttataa taaaattcat atatggaaat
    17761 attaatacta aataattaat agttgataga aaatagataa tatgctaaaa gcaaaaacta
    17821 atttagagcc ttgtaactgt ttatttgcaa ttataaaaac atctttaaac atattgacta
    17881 taatataaaa tattaactat aatacaaaac aatattaatt aattttctct acagctatcc
    17941 ctggtatggt tatttttcca cccatagttg attcataagt tatagttcca gcacttatac
    18001 ctcttatagt tatgtaatca tcctctaaca ctcttgaagg agttattgat tttttataac
    18061 tacatagtac gaccttatca taatttccag acacagctaa tcttatttgc acctcatcac
    18121 catcttcaat aacttgaata accttacctt caaattttac ctttttgtac ttataatcat
    18181 caggtgttct agctaattgg tcataagtaa taccagtatc atatcctttc ttctcttctt
    18241 cttctttttt acgttgttct tcagcctttt tagcttcttc agctttacgt tgattttcag
    18301 cttcaatagc tttcttttcg tcgtctttca ttttgaacca tggttcagca tcagacaatt
    18361 tgctatttaa agtttctatt tctgtttttt gagaatctat aactgatgtt tgattagaaa
    18421 tgacctcctc atggtcttca gaacaagctg gtgaggatat attgccaaaa aacacaccaa
    18481 aataaatgcc agtagagcaa tatcctttgt gctcttaaag aatttaatta ttttcttaga
    18541 gcttcctttt ctttcattac taaattcgtt accctcattt tttttagaaa acataataca
    18601 atctcccttt tattagatat attttatttt aaaatttaaa aacttaaaat aactagttga
    18661 ctaaaaatta tatattcata ttttcctaaa atatatttcc cctaagcata attttacaaa
    18721 ataaatcaag aagattcaat atattttgaa aaatgaggta aaaatgtcag attataatat
    18781 aattttcttg aaggtgaatt ttatatatta aatgaaacat aaagtatttt atttgtataa
    18841 aactatatta tgatgtaatt aaatgattca gtactttaga ggtggtaaaa tatagataga
    18901 tgaaagagca taaataaagt gatataataa aaaattaaat attaactata ataaaaaaat
    18961 atctggtact aagtataata caaaaataat atatcagaaa gaaggtgaag tatgggagaa
    19021 ctacaaaaaa ttccaggggt agggaaagca acagaaaaat ctttaatcat gttaggatat
    19081 acaactatta aatcacttaa agatgcaaac ccagcacaaa tgtatgaaaa ggaatgttta
    19141 atgcgtggac agcacataga cagatgtcag ttatatgtat acagatgtgc agtatatttt
    19201 gcatcaactg aaaatccaga accagaaaaa ttaaagtggt ggtattggaa agattaaaaa
    19261 atcaaaaaag ttagatataa aaaagagttg aatatccgtt taaataataa aaactaatac
    19321 tcaactcttt tttagtcgta aattttatgt aaatctattt gtatggctaa atatacccat
    19381 caataaatgt ataaatatac caatcaataa atgactaaac atactaccta acaaaggatt
    19441 aaataaatta cttaacaaag cattctaaaa caattaatta gaaactgttt cttcaagcca
    19501 ttttctacat tgcccaatat ttaccatagg gtcaaagcct tggtcttttc ccttatttaa
    19561 aagcatatca caagggaaag tatcacattc accacaatga ttaagttcct tactttcaca
    19621 gcaagtttta accttacatt ctccacccca aaatggtttt tccatagttg ggcaaccagt
    19681 gcaatttact tgttcttttt ttgtacaact gtcacaacag acaccacatc ttgattcaaa
    19741 catgttcaaa catcctttcc attatttaaa aatattataa aatgatttta gatgactaca
    19801 aaagtgcaaa tagttgattt taagtcatct aaatgttaaa cataaaatta ttaatactgg
    19861 taaatttata aaaactattc caaaaatatt tttgaatatt tcaaaacaca ataaattact
    19921 tcaaatccct ttgaatattc cataacacta tagattactt taaatcccct tgaatatatt
    19981 tcacagcatt atagattgct ttaaatctct ttgaatattt cataacacta tagattactt
    20041 taaatctctt tgaatattct acaagactat agattagttt aaattccttt gaatatttca
    20101 taacatcata aattagttta aatctctttg aatattctac aagactatag attagtttaa
    20161 atccctttga atatttcata acactataga ttactttaaa tttctttgaa tattctacaa
    20221 gactatagat tagtttaaat ccctttgaat atttcataac accatagatt actttaaatc
    20281 cctttgaata ttctataaca ctataaatta cttttaactt ttatataacc ataaagtttt
    20341 tatctggcac tttaaatgga gtttttatat caaatttgcc ttccatcgaa taaccaaact
    20401 taatttaatt acacattcca agagtcaaat attcattcaa tatatttgat aattctatgt
    20461 tatagccata attaaatata gattattaaa gttaaatatt tatttaatgt attgaatgat
    20521 tttttagcta tatttaatta agtttcatta tataatataa aaattgtttt tgcattaagt
    20581 tttaatataa cacataataa ttttaaataa taacattatt atatattttt ttattttagg
    20641 agtatatcta ttatatagtg agtagataaa acatataaaa ttcaaataaa agatatatat
    20701 ttttaaataa aagggatata aatttcaaac caaaaagaat ataaatttca aaccaaaaaa
    20761 tatctagcat ttaccattaa gaaataacat cattctttct aaaatttcta ttggcaattt
    20821 cagaaaatac tatagtagta ataaatgcaa cacatattgt aactatagtg tcattaacat
    20881 ttaaagcaga ttgctttata acccccatag cactacctaa catagaataa gggaaaaata
    20941 taccaacagc aggttttgct actattaatc ccataccaaa tagagaaagg caaagactaa
    21001 taccaatagg agttgcaaaa cttctaatct ttatagacat gtataattgt atagaagcta
    21061 ttgaaataga aataatccaa cctttagcaa tccaaccagt caattcttta ggtacactac
    21121 cagaaaaacc aaacatattt cctgcaacta tataaaagat aacaaagaaa acttgtgtaa
    21181 tagctgtaag tattgaaact actgtaagtt tagataaaaa gatatttttt aaattaactg
    21241 gcagtgtcat tacattattc caattatgat tcatatgttc aagcctacaa atatatgcac
    21301 aaaagattgc gattaagata ggaaagaaaa attccccata aaaaagacta acttgagtcc
    21361 ataagctgta ccattctttt ttgagtatgc cttgatttag ataaaaatta ccagaaccaa
    21421 tcaacacact tataagtggc aaagctaata atacatacca tataaaagaa ttttttaact
    21481 ttagaatttc tcccaaaact gacttcctta acatttaaat ccctcctata cttctttttt
    21541 taataaatga tttcttccaa tataataaat tagcattcca attaagaaaa ctaaaatcgt
    21601 aatagaaaaa ttcatatcaa ttctatagac agatgaacct aaaacattat cataagcata
    21661 acttaaaggt gataactcta ggtaataaga ccatataaac aatctacgaa taccttgata
    21721 aaacaaacct gatgtcaaac ctataaaact accaatcatg ccaaatgtaa ttgcaatcat
    21781 ttgatttgga attacagttg caatccatag gtgtagtgca atgatagcaa tacttacaag
    21841 aattgttcct aatgtgtatt ttaaaagtaa agatacagaa attgactcaa taacccctct
    21901 aaaatgtcca aacaacacaa tagataacac ttgcatcaat ataggtatag ataccaaaat
    21961 agcagaacat aaaaatttgg ataaataaat actatttaaa gatgtcacag aagattttaa
    22021 aagcttccat gtatctcctt tatgttctat atcgcttatg cgtgatgtaa ttattgatat
    22081 taagatagga aagaatagac catttaaact tgcaaaactc ataagcatat aggaatattc
    22141 aaatccacct aacatatctg gattacgtgt aatagcccta tttgaattta cgatacacca
    22201 cattatttca acagctacaa ataaaaaggt catcagaata atcttctttc ttttaagttt
    22261 ataaaattct agaccaaggt atttcattat aaagtcaccg ccttaccagt aagttctagg
    22321 aatatatctt ccaagctttt tttatgttct tctattctaa atacatctat atttgaatgg
    22381 acaagcatac catttatttt agccacatct gagtctttta aattttcaat agtcaagtac
    22441 ccattttgta taagtgacat atatccttta gtatttaata gcttttgtgc agatacaaca
    22501 ttcttagctt tgatagcaat ctgactttga cctctattat gaagttcttt tatgctatct
    22561 tgaaaaacca gttcgccatg atttattatt cctattgatg tggcaatttg gtcaatttca
    22621 cttaaaagat ggctagagat tagaacagtc atgccgtatt tttctggtag agattttatt
    22681 aattctctaa tttcctcaat ccctgctggg tcgagtccat ttgtaggttc atcaagtatt
    22741 aataatttgg gaaacttcat tattgccata gcaatgccaa gacgttgctt catacctaaa
    22801 gaatattgat taactttttt atttttttga ttttctaacc ttacaatttt taatgcttca
    22861 tttacatttt ttttaggtaa atctaagagt ctttgcatta tggtcatgtt ttcaagccct
    22921 gtaagatgac catagtatga tggagattct atcaaagaac ctatatcttt taaaattgat
    22981 attctatttt tttcatttaa ctctttacct aaaatattaa tatttccttg tgtgggttta
    23041 gcaagtccaa gaagcatttt aagagtggta gattttccag ctccattagg acccaaaaaa
    23101 ccatatacag ctccttgtgg aactcttagg tctatatcct ttactctaaa tattttattg
    23161 tattcctttg aaagtctttg tgttctaatt atcatttcca tatgtttcat cccctttttt
    23221 aatctgtgct tattgattct tttaacttat atcagtataa taacttggtt acatttcagt
    23281 tagctgaagt ttaccttaca ataaccttaa aagtctattt aggcaaagtt gtgaaaatgg
    23341 gtatatggta tactaaagga gggtgatgat tatggagtca ataaaagata aaaaaatact
    23401 tgtggttgat gaccacaagg aattattaaa aatgatagat gaaatcctaa gaaaagaggg
    23461 atttagtaga gtatttttag catcaagtta tgaagaagct gttagggtat ttagaaatgt
    23521 aaagccagat tgtgcaattt tagatgttgt attgccagat ggagatggtt tctctattat
    23581 gagaaaaatt agagagacat ctaagatacc agttattttt ctctctgcaa gaggtgaaga
    23641 tgaagataga ttgattggtt tgggattagg ggctgacgat tatatagtaa agccattttt
    23701 accaaaggaa cttactttaa ggcttgtggg tatattaaat cgtgtatatg tgcctataga
    23761 agaagaggag ttgccagtat ttaaactggg agattctgtt gttgtgaatt taaatagtgc
    23821 atgtgttgag aaagatgggc aagagatttc tttaacagct aaagagcatt cgttgctttt
    23881 aaagttgtat gaaaataaag ggagaattgt tactaatgat tcactatgtc aagccatttg
    23941 gggagatgat atgtatggat atgaaaatac ccttatggtt catgttagaa gggttagaga
    24001 gaagatagaa aaaactccat ctacacctaa acatcttatt acagtaagag gtcttggata
    24061 taagttgatg attaattaat tttagatatt agaataaaag aaatcaagag gagtgattta
    24121 attttggata gtgtaaagta catattgagg cgatttatag gttcaagtat cttgatttca
    24181 ttacttttta ttgtattaaa tatagcaggt tttcttctgt tttcatatat gctatttgta
    24241 tctaaatact ctgataattt agatacaagt gatagcagag aaataaaatc aaacttgatt
    24301 atgattgaag ataatttgat tttaaaagat ggaaagttta ttttagatga ttctagtaag
    24361 gaagtactac ataaaaataa agtttgggca atgttaattg ataacaatgg agatagaata
    24421 tggggatttg atttaccaaa agaaattcca agtcattata ctttgacaga tgtagcaaag
    24481 ttttcaaggt tctttttaaa ggactatcct gtgtatgtat gggaacatcc aaatggaata
    24541 ttagtaacag gttatccaaa ggacaaatac actaaattta accttactta tacgattaag
    24601 gaaatagaac aatttcctat gttaataata ggtatgtttc tggttaatgc aatagttact
    24661 tttttaatag ctctattcat aggtttaaaa atggtgaaat ctataaaacc aattattact
    24721 ggcataaagc ttatgtcaaa aggagaacca gtacttttac aagaaaaagg aatactaagt
    24781 gatatttcaa aatctattaa tactgtatct aaagagttgc aaatgaaaga tgaaaaactt
    24841 aggaagaaag aggaagctag gtctaactgg attgcaggaa tatctcatga tataagaact
    24901 ccactttcaa tgataattgg atatgctgga gaacttgaag aaagcagtag cctttcaaat
    24961 agagaacaag agcaagtgtc tattatatgc aatcaagggg ttaaaatcag agaattagta
    25021 aatgacctaa atttagtatc taaacttgaa tataatatgc aagcattgaa ttgtgataag
    25081 attagagttt ctgcgttttt gagagagctt atttctgagt ttataaataa taatttggat
    25141 aatgactttt atgttgaact tgatatacta aatgaagata ttattataga tgcagataaa
    25201 aaattattaa aaagggctat tagtaattta atacaaaata gtataactca taaccaacaa
    25261 ggatgtaata taagggttac ctctaagtct gatttagatt tttgctatat aattgttgaa
    25321 gatgatggaa aaggtatgag tcaagaaaga attaatagtt tattaaagag ccaaaatgga
    25381 ctaagtgagg catatgccaa aggtcaaaat catggtctag gtattttgat agtagctgga
    25441 attattaatg cacatagagg taaattagat attatgagta ttgatagtca gggactaaaa
    25501 acaatactaa aattacctct aattaagtga tattttataa aataataaca gataagaatg
    25561 aagaatgaag aatgaaaata ttttgaaaat aattttattc tttattgaca aaataactct
    25621 attagagtag aataaggata aattcttttc ttgtcaagtt ttattaaagt aaagagtaac
    25681 ttgtgcttta tgcgcttatg gctgagttac tcatggtatc aaaattttca tagaaataat
    25741 attttggaat tattgtaagg ttattaaatt ctttagataa ttccattttt tttatttttt
    25801 agttaatatt taattttatt attgacaaaa aaattctact aaaatagaat tatggtatag
    25861 tgttttttaa ttttaagaaa aaatataatg acatcctaaa aaagttttaa ttatacgttg
    25921 ttctgtgtag ttataatagc ttctatgtaa ctattgtaag tatattttat tataattatt
    25981 tatttaaagt acgataaatg ttttaaattg aagtattttg caccattgag ttctactaaa
    26041 gtagagtttt tgtgtagtat ttttagaaat aaca
//
LOCUS       DAMJWO010000061        26072 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.062, whole genome shotgun sequence.
ACCESSION   DAMJWO010000061 DAMJWO010000000
VERSION     DAMJWO010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26072
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.062"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(224..1072)
                     /locus_tag="PC366_002530"
     CDS             complement(224..1072)
                     /locus_tag="PC366_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDF2578031.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEREYKDRIDI
                     SGDEFYKRLREENVYPKTSQATYAQFKEIFEKYTNEDREILYIAGSATATGTYQSAVM
                     AKNDVDGKIYTYDSNLLCMGTGLLVIKAGELASEGKSVDEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMQDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
     gene            complement(1108..1578)
                     /gene="trmL"
                     /locus_tag="PC366_002531"
     CDS             complement(1108..1578)
                     /gene="trmL"
                     /locus_tag="PC366_002531"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HDF2578032.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPEPLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            complement(1772..2824)
                     /gene="nth"
                     /locus_tag="PC366_002532"
     CDS             complement(1772..2824)
                     /gene="nth"
                     /locus_tag="PC366_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HDF2578033.1"
                     /translation="MKNVNLKEINEKDVIVEEDINLKGMDKKDVIEKEEVNKKSIDKK
                     DIIEKEEIDKKNVKKVEVQKEIDKMISKKDEIIDEKDIENFRYIEEDKKSIKVSKKST
                     KKGETEKKTKKSSSNKATQKQSKEVKSKSKIKSESANKKDVNKILDELEKLYPDAKCE
                     LNYGTAFELLIATILSAQCTDVRVNKVTSELFKKYNTARDFANLSIEEISKEIKSCGL
                     YKSKSQKIKDTSEQLCELYDGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDT
                     HVFRVSNRIGIVDEPNPQKTEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASC
                     PIKEDCNYYKELNETK"
     gene            complement(3021..5258)
                     /locus_tag="PC366_002533"
     CDS             complement(3021..5258)
                     /locus_tag="PC366_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2578034.1"
                     /translation="MKYNNTSEINPLDYILGQERAVEAMELGLKINNPAYNIYIAGEP
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNRLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDKSDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQTYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNESSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEDNEEGIARFIAYQCDKNNLRHFTKSAVEEVIKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTEQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVSIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVRDGKFKIYTVERVEEAIEILTDVKFEEIKKLVKEKLISFSKIQ
                     TVSKE"
     gene            complement(5364..6278)
                     /gene="queG"
                     /locus_tag="PC366_002534"
     CDS             complement(5364..6278)
                     /gene="queG"
                     /locus_tag="PC366_002534"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HDF2578035.1"
                     /translation="MDNKELKAFCNLIGLNCVGVAGVDKYDNLEKILKDRQQKGYLTG
                     MEEPIIENRINPRHIMKDANSIIVCAFPYHINRQEKNKNSNLSKYCHGKDYHIVVKDF
                     LQQICDYISKTVTDFKYKLFVDNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYVFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSEK
                     EKVVLKNGKKVFGCDICQEVCPHNVEMPTTHILEFKENIIDYLDYDEIQNISNKEFKR
                     RYGDRAFSWRGRNIIKRNMEIILDKYDD"
     gene            7278..7682
                     /locus_tag="PC366_002535"
     CDS             7278..7682
                     /locus_tag="PC366_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDF2578036.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     FLFDFIDKDNPRVEIELYPVSKYDISYNIFEK"
     gene            complement(7939..8934)
                     /locus_tag="PC366_002536"
     CDS             complement(7939..8934)
                     /locus_tag="PC366_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDF2578037.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRNKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADEVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKDYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(9186..10022)
                     /locus_tag="PC366_002537"
     CDS             complement(9186..10022)
                     /locus_tag="PC366_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HDF2578038.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     DEKDIIKFQEIRKENNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHIGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKRELKMIKEILS
                     SK"
     gene            complement(10510..11073)
                     /locus_tag="PC366_002538"
     CDS             complement(10510..11073)
                     /locus_tag="PC366_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2578039.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            complement(11171..12100)
                     /gene="glsA"
                     /locus_tag="PC366_002539"
     CDS             complement(11171..12100)
                     /gene="glsA"
                     /locus_tag="PC366_002539"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HDF2578040.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
     gene            complement(12665..14332)
                     /locus_tag="PC366_002540"
     CDS             complement(12665..14332)
                     /locus_tag="PC366_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HDF2578041.1"
                     /translation="MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDGNKRVILIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEE
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
     gene            complement(14406..15161)
                     /locus_tag="PC366_002541"
     CDS             complement(14406..15161)
                     /locus_tag="PC366_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HDF2578042.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKY
                     KERISKLGLSIGIHLPMELNTCENIEYIRNSWINFIEKIEFELKGFDIRYFNLHLGYV
                     MTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDAYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EVLTLDAEYLVLEINYEDIEDTISKLNNIVREG"
     gene            complement(15171..15707)
                     /gene="lepB"
                     /locus_tag="PC366_002542"
     CDS             complement(15171..15707)
                     /gene="lepB"
                     /locus_tag="PC366_002542"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDF2578043.1"
                     /translation="MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            complement(15873..16409)
                     /gene="lepB"
                     /locus_tag="PC366_002543"
     CDS             complement(15873..16409)
                     /gene="lepB"
                     /locus_tag="PC366_002543"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDF2578044.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTI
                     LGKVLVRLYPFSKIGTID"
     gene            complement(16509..17819)
                     /locus_tag="PC366_002544"
     CDS             complement(16509..17819)
                     /locus_tag="PC366_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HDF2578045.1"
                     /translation="MTELPKEFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPE
                     IYPDTKKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF"
     gene            complement(17898..18614)
                     /locus_tag="PC366_002545"
     CDS             complement(17898..18614)
                     /locus_tag="PC366_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HDF2578046.1"
                     /translation="MKLDLFLLAIVPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLE
                     KYMNHSKKVFFGNLRKKKKK"
     gene            18859..20130
                     /gene="sleC"
                     /locus_tag="PC366_002546"
     CDS             18859..20130
                     /gene="sleC"
                     /locus_tag="PC366_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic protein SleC"
                     /protein_id="HDF2578047.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIVAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGADTENAVKIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            complement(20600..21256)
                     /locus_tag="PC366_002547"
     CDS             complement(20600..21256)
                     /locus_tag="PC366_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578048.1"
                     /translation="MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKF
                     AVLATMGDLLGARILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDGM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(22449..22859)
                     /locus_tag="PC366_002548"
     CDS             complement(22449..22859)
                     /locus_tag="PC366_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578049.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKLESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEQEL
                     EKIKTEGLKIMKPITIENEDGSQISIAYNYAAID"
     gene            complement(23075..24457)
                     /locus_tag="PC366_002549"
     CDS             complement(23075..24457)
                     /locus_tag="PC366_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HDF2578050.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNTSTENYTLKKASDSTGKNNSDEFEIMSNIE
                     NIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESF
                     GLTKNEQSDKSGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHE
                     ESSMSKVTNSENSEETYVNKSSNSKDVLYTDSGEVSIEQSNYNDNRFVISRKGNLLAV
                     NKEQYRTWIE"
     gene            complement(24468..24827)
                     /locus_tag="PC366_002550"
     CDS             complement(24468..24827)
                     /locus_tag="PC366_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2578051.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(25032..25811)
                     /locus_tag="PC366_002551"
     CDS             complement(25032..25811)
                     /locus_tag="PC366_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HDF2578052.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTIISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
BASE COUNT         8493 a         4765 c         2478 g        10336 t
ORIGIN      
        1 aattttttta tatacaattt acaagtacat tttgaaattt ttttaataaa tcttactata
       61 aaaaagtgtg caatagattc ttatctattt acacacttcc ctacaaacta aatctaatat
      121 atcaacactt aatttcatcc aaaataaatc caatttaaca tctcaataat taatattcta
      181 tcctaattta ataaaaaaat aaataatgtc atccaaaaat atattattta ttttttaagc
      241 atatgatacc agtgacacca ggaccagcat gcgcacctat acacacacca atttggaaaa
      301 atctaatttc tttaggtctt aattcatctt gcataacctt agataattgt tctttttcct
      361 taaaatcatc actatatcct atatacacaa tttggtctga taaatcatcc ccacaatttg
      421 attttatcaa ttccatcatc ttagaaatta cattcttctt tcctcttact tgagatattt
      481 gcgaaactag tccatctctt atttcaagaa tcggttttat atttaatata cttcctattg
      541 ctgccttagt agatgatatt ctacctccct tttgtaaata ttccaatgta tctactgaaa
      601 atataacaaa agccttctct tttaattcat ccaaaacagg taatatttca tcaacagact
      661 ttccttcact tgcaagttct cctgctttta ttacaagtaa accagttccc atacaaagca
      721 agttagagtc atatgtatat attttaccat ccacatcatt ctttgccatt acagcacttt
      781 gatacgtccc tgtagctgtg gcagaccctg ctatataaag tatctctcta tcctcatttg
      841 tatatttctc aaaaatttcc ttaaattggg cataagtagc ttgagaagtt tttggatata
      901 cattttcttc tctaagcctt ttataaaatt catctccaga tatatcaatt ctatccttgt
      961 attctctttc ctccagtata actgttaatg aaactatatc tatatcatat ttatctaaca
     1021 aatcttttgg cacgtccgat aaactgtcac agattatctt tagatttttc attaagtatg
     1081 ctcctttctc atttaggctt gttgaaacta cctcatattt gggtatccta tttgtcttaa
     1141 agcctcgtac actacaatag caactgaatt tgataaattt aatgacctag ccttttcaac
     1201 atccaacata ggcactctaa tacaagtatc catatttgct ttcaacaaag gttctggtaa
     1261 tccctttgtt tctttcccaa atactataaa acaattttct tcatatttca catctgaatg
     1321 tgactgttta gcctttgttg tagaaaaaaa gtatttacta tttggatact tttcttgtaa
     1381 ttcttcaaag ctatcgtaat attgtatatc agctatatcc caatagtcaa gcccacatct
     1441 ttttaggtgt ttatcatcca atgaaaaacc cagtggtttt actaaatgta aagttgaacc
     1501 tgttgctgca caggttctta ttatatttcc tgtattttga ggtatttctg gttctactaa
     1561 tactatattt aatgacattt taatcctccc taagtatcgc ttttatttat caaattttat
     1621 tttataaaca gaataacaat aatattatac tattatataa aataatgtta ataataattt
     1681 ttatttcatg tatataatag ttttttatct aacattttca caagtattat tatatcagaa
     1741 aatccctctt gtacaactta ctttctaaaa gttatttcgt ttcattaagt tctttataat
     1801 aattacaatc ttcttttatt gggcaacttg cacattctgg atttctagct ttacacattc
     1861 ttcttccatg aaaaattaat acatgatgtg agtgtgacca tctttctttt ggtatagctt
     1921 ccataagtgc aaattctgtt ttttgaggat ttggctcgtc cactattcct attctattgc
     1981 taactctaaa tacatgagta tctacagcta ttgctggatg attaaaagcg ttactaagta
     2041 caacccctgc cgtttttctt ccaacaccag gtaattttat aagcttttct aagctatcag
     2101 gtacttcacc atcatataat tcacatagct gttcagatgt atcctttatt ttttgagact
     2161 tgcttttgta aagaccacaa ctctttatct ctttactaat ttcttcaatg ctcaaattag
     2221 caaagtctct agctgtgttg tactttttaa acaactctga agtaacttta ttcactctta
     2281 catcagtaca ttgtgctgat aaaatagttg ctattaaaag ttcaaaggct gtcccataat
     2341 ttaactcaca tttagcatct gggtacaatt tttccaactc atctaaaatc ttatttacat
     2401 cttttttatt ggctgattca cttttaattt tagacttact tttaacttct ttgctttgtt
     2461 tttgtgtagc cttattagaa ctacttttct ttgttttttt ctccgtttca ccttttttag
     2521 tacttttttt acttactttg atactttttt tatcttcttc aatataccta aaattctcta
     2581 tatctttctc atcaattatc tcatcttttt tactaatcat tttatctatt tctttttgaa
     2641 cctcaacctt ctttacattt tttttatcta tctcttcttt ctcaattata tctttcttat
     2701 ctatactttt tttatttact tcttccttct caattacatc tttcttatcc attcctttta
     2761 gatttatatc ttcttccaca attacatctt tttcatttat ctcttttaga tttacatttt
     2821 tcataattat ccccctttaa aataccaatt tataaaacac tatttataaa tagtttagtc
     2881 atatcaacaa aaaataaaca tcaatatata aaacatacaa aataagaatt taatttatat
     2941 atatttacaa aaaaagcaaa aacctattaa agttcttgct ttttattata cataaatacc
     3001 cattaaattc tataataaac ttattctttt gacacagttt gtatcttgct gaaagatatt
     3061 aatttttctt ttaccaattt ctttatttct tcaaatttaa catctgtcaa tatctctata
     3121 gcctcttcta ctctttcaac agtatatatc ttaaattttc catctcgcac tgcatcatta
     3181 acttcatctg ataaaacgag atttctttga ttttttctag gaattatgac gccttgctca
     3241 ccatttaacc ctttagtttt acatatagaa taaaatcctt ctatcttttc acttatacca
     3301 ccaactactt gtatatcacc cttttgattt atagaacctg taacagcaat attttgttta
     3361 attgatactc cactaagaga tgataatagt acatataatt ctgcagaaga tgcactatct
     3421 ccatctattc caccataatt ttgttcaaaa caaacatatg cgtttagtga caatagtaaa
     3481 tcctgtgcaa aattctcaga aagatagcca cctaatataa gcactccttt gttatgtata
     3541 gagccactca tatttacttc tctttctata tttactatgc ctttacttcc tgggctagtg
     3601 gtcgctgtaa tccttgaagc tctaccaaaa gagtattctc ctgtacttaa gactgacaga
     3661 ccatttatca ctcctacttt tcttccctct gtttctatta gagtaaatcc attttcaatt
     3721 gattcatcca tatgtgtttc cactctattg attctttttc tcttttcact tattgctttt
     3781 ttaacatcac actgctctgt atactccgaa tttctaaact ctgcataagc acttccttct
     3841 attacaactt ccattatttt attaaactta gttgatagtt tttctaaatc accagataat
     3901 ctagtgctaa atttaataac ctcttcaact gctgatttag taaaatgcct taaattattc
     3961 ttatcacatt ggtatgctat aaatcttgct attccttctt cattatcttc atttttatcc
     4021 atttcactat caaagtctac aaatacttta aaatattttt caaaatcttc atcatatcta
     4081 tataaaatat catatatata gtggcttcca atcagtacta atttaacatc caatggcata
     4141 ttttctggtt taattgctgt ttgtgtttcc aatattactt ttttagtctg caaagtcttt
     4201 ttaagaattt cccaagacat tgtatatttt agtaattggt ctgcataaag tactaaataa
     4261 ccaccattag ccctatgaaa tgctcctgat aatagttttg tgaaatcagt ctttatattt
     4321 ccatttgcat aatcatactc tgcctttcca aatagatttg ctggacttgg gtttatctct
     4381 actacaacag gtgctgattc tttattcttt gagctttcat tgtctacaaa taggttaatt
     4441 ttgtatttaa taaaatgctc tttatcatac ttatctttta actcctcttc atctaaatag
     4501 aacaaataca tatattctat tatatctttc tttatatttt ccagataagt ttgaatctta
     4561 tcataatttt catatttttc acacaatctc ttgatatgag gttctactac aagtttagct
     4621 atctcttctt caagctctaa cactgctttt tcagctattt cttctaagtt tctaatttta
     4681 tatacgacct gtatcgccat attttctagt tctcttttag ctttgtaaaa ctcttcatca
     4741 gacttatcac tttcatcttc ctcttctttc aaagggataa aaactattcc cattttactc
     4801 tgttttaatt taaatccttt ttcttcccca tatttcttaa tttgcttcaa aagcatatct
     4861 ttttctattt catattcatc tagaagtcta tttttttcta tttcaaaatt ttcactttca
     4921 aacgcatttt taaaatcttc taaaagactt tcaattaatt tctccatatc tttcttaagt
     4981 tctcttccaa accccttttc taattcaact ataataggct ctctagggtt ttcaaaatta
     5041 tatatataac accaatcttt atgtgtattt tttttggatg catattcatt taaaaccttt
     5101 aaggcataag tacttttacc agttccaggt tcaccagcta tatatatgtt gtacgctgga
     5161 ttatttattt tcaaccctaa ttccatagct tctacagctc tttcttgacc caatatataa
     5221 tctagtggat ttatttcaga tgtattatta tatttcaata ttcccccacc tccccatatt
     5281 taactttaat gatataatat gacttttaca caacaagtgt taaagtaaat acacattaaa
     5341 gtatatgaaa cagactctta ttattagtca tcatacttat ctaaaattat ttccatattt
     5401 ctctttatta tatttctccc tctccagcta aaagctctat ctccatatct ccttttaaat
     5461 tctttatttg aaatattttg tatctcatca taatccaaat aatctattat attttcttta
     5521 aattccaaaa tatgagttgt tggcatttca acattatgtg gacatacttc ttgacaaata
     5581 tcgcatccaa ataccttttt gccattcttt aaaacaactt tttctttctc tgacaaatct
     5641 cctttttttt gagttatata tgataaacat tttttggggt tcatatcata atttcccaat
     5701 atagcatttc ccggacaata ttttacacac ttaccacatt taaaacaact tttttctagt
     5761 ggtttatctt cttcaaattt ataattattt actatatacc ctataaatac gtaagaacca
     5821 tattcatcag ttatgatatt attatttatt ccaaaatatc ctattcctga taaataagct
     5881 aaatacctgt caactaatgg tccattatca acaaataact tgtatttaaa atctgttact
     5941 gttttagaaa tataatcaca aatttgttgt aaaaagtcct ttactacaat gtgataatcc
     6001 tttccatgac aatattttga taaatttgaa tttttattct tttcttgtct atttatatga
     6061 tatggaaatg cacagactat tatagagtta gcatccttca ttatatgtct tgggttaatt
     6121 ctgttctcaa ttattggttc ttccatacca gttaaataac ctttttgttg tctgtcctta
     6181 agtatctttt ctaaattatc atacttatct acccctgcta ctcctacaca gtttaatcct
     6241 attaaattac aaaatgcttt taattcctta ttatccataa aattattcct ttttaatcta
     6301 attgactttt taaatttatt taattttttt agtcttttta accttttcta gctactaact
     6361 cttttaaata cttcgtcttt tttatttatt taactttttt acctactaac tcttttagat
     6421 acttcgtctt tttacctatt tagtttttta cctactaact cttttagata cttcatcttt
     6481 tttatttact tatttaactt ttttatttac taactctttt agatacttcg tctttttcat
     6541 ttacttattt aactttttta tctgcttaac tcctttaaat acttagtctt tttatctatt
     6601 taattatttt acctactaac tcttttgaat acttagtctt ttttatttat ttaatttttt
     6661 tatctactaa cgcttttaga tacttaatct ttttatctat ttaatttttt tatctactaa
     6721 cgcttttaga tacttaatct ttttatctat ttaatttttt tatctactaa ctcatttaga
     6781 tacttagctt ttttcattta cttatttaac ttttttacct acttaactct tttagatact
     6841 tagccttttt aatctattca acctttttta cccacttaac cttcttacct tttaatataa
     6901 actctaaaac ttcaaatatc attagttata ttttgacatt cttcctatag ttaatgcaaa
     6961 aagattgatt ttttcttata attaatatcc catttacatt gccatttatt aagtctttac
     7021 ttggcttata tggatttctt tttactctct ttactaaacc tatacttatt aatattatga
     7081 aggtcttata atagtctaat atgaatatgt ccatcatata tcaaatttta aaatttgtaa
     7141 gcaaaatact tatcttatat tactacatct aaagtggaaa attttacaaa caagccctgt
     7201 aaaaacactt taaataacaa tttgctttta aatcatatac agattataat aaatactgta
     7261 taaggatggt gaaaaatttg attaaaataa caattccagg tagacctatt agtaaatcta
     7321 attttaagct tcataacata aatggtcaag catggatgcc ttcaaaggga aaatattcta
     7381 agtatcttgc atacgaaaac atgattgcag gttttataaa ccaacagtat caaggggaaa
     7441 ctgttgaaga aaatctaata acagtcttga aattattctt tccaaataag agaatggggg
     7501 atttacataa ttatccaaaa agtatttgtg atggtattga aaaaagtgga ataataaaaa
     7561 atgataaaca acttaagcca gtatttttat ttgattttat agataaagat aaccctaggg
     7621 ttgaaattga actttatcca gtatctaaat acgatatatc ctataatatt tttgaaaaat
     7681 aaagatttta tgtgttattc gacattatat tgatactcca gtatttgaaa ctatactaat
     7741 acaacaataa taattgtgtt atgtctatac tcaaacaaat gtttttaaaa agcattaagc
     7801 aaatatttaa taagtattaa acaaatatta aatttatata atagctataa ctatgtaaat
     7861 ttaatatttg tatataagac cacatctaat aaaaagaaat cggagtaaat ttaatacacc
     7921 gatttcaata aataaaatct atcctagctt ttcaacaaca gtcttaagca tttctcttat
     7981 aggaagttca tatggacatc tactctcgca aagcccacag tcaatacact cagtaggttt
     8041 aacatccata acctcatatt tttctttagc ccactctttt aatccatatc tagtataata
     8101 accttcacat aaaaaactca atggtatatt tattcctaca gcacaaggca tacaatattc
     8161 acatcttcta cagaattttt tacctaaaga atttcttatt tcttcaattt ccttattatc
     8221 tttttcatct agaacaagat tttcaagtac agcgacattt tgtctaacct gttcaacact
     8281 ctccatacct ggtataacta catctatgta atctttagat agtatatatt taatagccag
     8341 tgttgcattg tctaaagcac ctccagctaa aggtttcatt actattatcc caattccttt
     8401 ttcatgagct tttttaaaca cttcatctgc ttgtccttca actatattgt aagggaattg
     8461 tatagtgtca aattttccat cttctatagc tttttctata gtatttaaat tgtgactagt
     8521 tataccaata tgttttatct taccttgctc ctttgcctct aaaagggcac tataagccat
     8581 tttatcttta aaaagattat catactcctc ttctttaaca ttatggaatt gatataaatc
     8641 tataaaatca gttttaaaat tatttaaact tatttcaaca tctctcttca ttgaatcata
     8701 atctctggac atacttttag tagctaagaa aaatttattt ctttttcctt caatggcaat
     8761 tccgattgct tcctcactta ttgtataccc tcttgcactg tcaataaagt ttattccttg
     8821 tttttctaac tcatttataa ctaagttagt atcatcttga gtaattcttt gtattggaat
     8881 gcccccaaag ccaactctct ttattttcat gttagtattg cctaaatttc tcatatcttt
     8941 ccccacctaa cttttaataa ttttttatat aatataaata tgttaccttt aattatacaa
     9001 caaattatga gaatctttgc aatatattta catactattc ataatataat catactttat
     9061 acccagttaa tttgtataca atttttgtta ttcctatcca ttaatttaaa ttatcacatt
     9121 tcatgattgt atctccacct taattatgtt gagggcggag tatttcacat atttttaata
     9181 aaggtttatt tactagatag tatttctttt atcattttaa gctctctctt gtgaccttca
     9241 tcatcaaaag gagtttctaa gaaaaatggt aaatgtttta gactaggatg ttccataaaa
     9301 tcaattaatg cttttaatcc tatctttcct tcccctatag gagcatgtct gtcttttttg
     9361 tctccaaatg gcatcatact atcatttaga tggacagttt tcaatctttc tatgcctata
     9421 accttatcaa attcttccaa aaccccatct aaatcattca ctatatcata accggctgaa
     9481 aaaatatgac atgtatcaag acacacacct attttttctt tatgctcaat tttgtctatt
     9541 atacttttta attgctcaaa tttaaaacct atttcagttc cctttcccga catagtttca
     9601 agaagtatag ttatattttc atcacccttt atggcattgt tcaatccttt tactattcta
     9661 tctataccaa aatctacacc accacctata tgacttccag gatgaaaaca catgtattca
     9721 attcctaatg agtccatcct tcttatatcc tcatctatca cccttgttgc aaattcgtat
     9781 acatcatcct ttgtaccacc cagattcata gtatatggtg catgtgcaag cagtggtgca
     9841 aaattatttt cttttctaat ttcttgaaat ttaattatat ctttttcatc aaattcttta
     9901 gcatttcctc ctcttggatt tctactaaaa aattgaaatg tatttgcacc aatatataca
     9961 gctgtctcag ccgcattagc aaatcctttt gctattgaaa gatgtgttcc taatttaatc
    10021 atattaatct ccttttattt gtactacgac ttgtactcaa ttttaatttt gaactactcc
    10081 accttaacta tatttagcca acatatgaag atggagattc ctatttgata gtactttttc
    10141 actaaaaatt cataagctct aagggatgtt ctatcccaac taatctcatt cctcttttaa
    10201 catatttcta gcattgattt aatttatatt aatttttaat tttaatattt acactttaat
    10261 tatacccatt ttaatcaatt tcaaatatta taatcttaca tactttgtat attatctaag
    10321 cacttctcag atagtgtata catcttacac tatacatatt atttacaaat acaataggta
    10381 taagaaaaca aaaaaataga gattaaaaat cattgtttta cccataccaa aaactatttt
    10441 ttgattatta agtaaatttt gatgttcaat ctctaatatt atatctttaa ttaatccata
    10501 attaattctc taactaggac attcctcctc aagagtagga actataacca tagctatatc
    10561 atacttagaa ccttcaacat tgtgttgtct tttatttaaa atttcatcta tctttgactt
    10621 catagtgtca ctaagttcaa ctaattcatc atgagtaaga gaaatatcat gataatcaac
    10681 tatattttca ttttctaaaa catcttcctc tgctgcctta taaaaaactt cactcatatt
    10741 ttcaaatttt gatatgtaca attcttcttt ttcttcccca ttgtctaaag aaaaattaag
    10801 tatcctattc cctataacca cattttttgc acttggataa tagtactttt ccacaatccc
    10861 cgactttatt ttttcctcaa ctaattctaa aataccaact ttgtataaca tttttatatg
    10921 gtagtttatt tttgcatgag gttcttccaa taattgagat aattgttttg ctgacaatgg
    10981 cgatttgtca aatgctttta gaatatctat tctacgtgga tgcgcaatag cctttatgca
    11041 ctccaaatct cgtaatacca atacctcttt cattgacccc tcctaaaaaa tttatttaat
    11101 tcatatttct ttacaattta attatatatt aaattatatg ttgttgtcaa aaaaatcctt
    11161 tcttaatatt ttaaaaaata tttaatttga gtttatttga caactcctct aaaactttaa
    11221 ctcctgcgac gctgttacct tttttgtcaa gcgcaggtcc ataaacacca atccccatgc
    11281 gtcccggcac agaagccatt ataccacccc caactccaga ttttgcagga atgccaactt
    11341 taatagcaaa ttccccagaa gcatcataca ttccacaagt catcataaat gtcttgacaa
    11401 tcctagaaac catttcactc attaaatgct caccattttc tatatctact ccataatttg
    11461 caagatttat tccaattctc gctaaatcta cagaatctat ctcaattgag cattgtttaa
    11521 aataaaggtc tagaacatct tctacattcc ctctgataaa tccatcactt ttcaataagt
    11581 aagccatagc tctgtttcta tctccagtca ttttttcaga cttatagaca tcatagttta
    11641 ttcctatatt atcatttttt gctaactttc taaagaaact aagcattctt tcttcttttt
    11701 cttctaaaca actcccattt ataagggaag tagttactat agcccctgca tttatcattg
    11761 gattacaggg tttttttgtg tcattaattt caagtttcat tattgaatta aatgggtccc
    11821 cacttggctc cattccaacg tttgaaaaaa cgtcttccca atcattatcc ataagtgcca
    11881 tagcaagcac aattggtttt gaaatacttt gtatagtaaa ctttgtgcta cagtttccag
    11941 cactataaag attattttcg ctatctatga tacaaattcc taaatcattt cttctagcgt
    12001 tttttaattc tggtatgtaa ctagcgactt gcccataatt agtatacttc ttattagaac
    12061 ttataatttc ttttaataat gtctcatcta acgtattcat atgcacctct tatattatgt
    12121 tatatattct attttagcac aagtttgtac tataataaaa cagtgttaaa aaaaattata
    12181 ctttaaaact attttctaca agaatcaatt catttttcaa acaatttaaa cagtttaaat
    12241 agcttaataa tttaataatc tagtaattta gtaatctaat aatccagtaa tttaaattct
    12301 tataacgtca aaaatttcta acctaacatc ttttactctt ttactctttt actcttttac
    12361 tcttttactc ttttactctt ttactctttt actcttttac tcttttactc ttttactctt
    12421 ttactctttt actcttttaa aaaattatca cataaactaa caaaatatta aacaaaaaag
    12481 taaaatttaa aataaaaagc ttgcttcata caaaagtata aaacaagcct ttttatatat
    12541 caactcaaac tttaaaatct gtatcaattt aattctccac tttacactta atatacttaa
    12601 cataaaccaa tcacactact tgctatgcca tttaatcttc ataaaacaat ctataataca
    12661 catattaatc aactatttta cttcctccaa taaattccct aagaattgaa atacctggta
    12721 tgtcagaagt atcgtccaat tcaacaaaat actgcaaaaa ctttagtaat ctagtagctt
    12781 caatatgtgc aggattatct tcctttatct cttccaacaa aggtttcgca aatcgtttta
    12841 aaactgctaa ttcatataca caagcagagt taaatatagc atctgcctcc tcttggtacg
    12901 ggaatatatt cttcttttct cctcttctaa ctgatgccca ttgtaaaata gtattatcag
    12961 cactatatcc tctaaaatta tagtctctaa caattcttct tatcattctc aaatcagcag
    13021 tagggattcg attatggtca tccaaattta tttgagtaag ggcacttatg tatatcttaa
    13081 atttatcttc atctggtata gatgatgtta aaataggatt tagcccatgt ataccttcta
    13141 atataattgg ctgatttgaa tctatcttta tttttttacc agtgtattct ctcttacctt
    13201 ctttaaaatt gaatcttata tcatcaattt cttcaccagc taaaagtttc tttaagtcta
    13261 agttaaactt ctctaaatct attgcataaa ttgattcaaa atcataattt ccatattcat
    13321 ctaaaggagt atgttttcta tctataaaat aatcatctaa agaaattgaa ataggattta
    13381 aattatttac tctaagatgt attgataatc tgtgagcaaa acttgttttt ccagatgaag
    13441 atggagctgc tattaaaatt actctcttat tgccatcctt tatcatatcc gctatttggg
    13501 ataacttctt ttcatgcaat gcttcgaatg tccttattat atctccatat tcattgtttt
    13561 ctattatttt gttaagagat actaccttgt caattcccat aagtcttgac cattcttctg
    13621 cttcataata tacacttgat agcttaggtt gaggtacaaa cttcatagga agagtcttat
    13681 cttcttcact aggccctaaa attataacgc ctccattata aagcttaata tcaaatgatt
    13741 ttatataacc agttgatggc aacatataac cataaaaatg gtctatatag tttctacact
    13801 tatatacttt agcactatca tactctttgt atttcaaaag ctctgccttt tcatacattt
    13861 cattattttc aaatatagaa atagcttcat ttcttgtaac ttcaattttt tctataacat
    13921 aatcgttgtt tactatctct ttcatcttgt tttttatatt ttcaacatct gcttctttaa
    13981 gctttctatc tatatgaact tcacaatata gcccatctga tagtgaatgt tctattgtaa
    14041 ctctgctatc ccaaaagatt tctctacaag ccattacaaa tataaatgac atgactctaa
    14101 agtaaactct ctctccatct tcattagtag tgtctaaaaa atttatctca caatccttct
    14161 taactctaca atttagctct tttagtttat tgtctacaac tgcaagtgtt atataaccct
    14221 tatgctcatc acaaaattct ttcgctatat ctcccaatct gattccaggg gaattttctt
    14281 ctaatgaata ttccttatct tttccttcta tttttaagtt tatttttttc acttcaacat
    14341 ctccttcctt ttgatgaata taaattttag ttaatgaggc atatcaacaa gataaagaga
    14401 ggtatttaac cctctcttac aatattattc aatttactta tagtatcttc aatgtcttcg
    14461 taatttattt ctaatactaa atattctgca tctaatgtta agacctcttt aatcccctct
    14521 tcagataaaa ttcctcttcc tataccaaca tgtgtatcat tgataccatc attatcactt
    14581 aagtgtatca gtcttatttt atcctttaag ttctttacat aagcatcctc atcaattaaa
    14641 cagtgtccag tatcgtaaca aaaacaaatc ttagaatttt taatcctctt aaatatatat
    14701 tcaaaatcat aagatatatt tccaatattt gaaaaatccc caccttttga ataagtattc
    14761 tctatacata catatgaatt tgtatttaat ttatctaaaa aatccacact atttcctaaa
    14821 tatttgtctc tattctttct aactctattt gtcataacat atcccaaatg aaggttaaaa
    14881 taccttatat caaatccttt tagttcaaat tctatcttct caataaaatt tatccatgaa
    14941 tttcgtatat actctatgtt ttcgcaagta tttaattcca taggcaagtg tatccctata
    15001 gataatccta acttagaaat tctctcttta tatttacata actcgctaca ttcagatata
    15061 ttgtcaattc caatctctaa atgagttatt tgctttatac tctcacaaat gtttaaagcc
    15121 tcctcaatat taaacaataa ggacgctata ccaactgcca tacaaatcac ctactcaaaa
    15181 atacctatat ctgtaaaagg aaatactctt aaaataactt ttcctttaat attttcttca
    15241 tctaccaatc ccacttcttt atatctactg tctaaactaa cttctctatt gtctcccatc
    15301 gcaaatactt ttcccttagg aatcaccata tcaatatcgc cttcagtata attatcatgt
    15361 atatatgaaa cttcatttaa taacttacca tttatataaa ccttagaatc cttaattttt
    15421 agatggtcac caggaacacc tataaccctt tttacaagct cttttttcct tccattctct
    15481 tgtaataaat cagtcttaaa tatcattata tctccacatt ttggttctga taacttatat
    15541 gtcatcctat ttgctaccaa ataatcatgt gatttaagtg tcgggtacat tgattctcca
    15601 tttactagtg ttggttttat aaaacgagtt ataataaatg caaaaaaaag tgcagtaata
    15661 attattttta tccactctac aatctcttct ttaatagttt cattcattca caaattctcc
    15721 tttatagtta tattatcttt attgataatg tctcttaaac actatctttt agataagtct
    15781 actaaataag gtgttgtctt ttttatatag acaactattg tgtatggtct ggtgatttca
    15841 gctaatcagc gattgctcca aattttatat gtttagtcaa tagttcctat cttagaaaat
    15901 ggatacaatc tgactagaac ctttcctaaa atggtatgct cgtcgaccaa tccaacctca
    15961 tcgtatctac tatctaaact tttttctcta ttatctccca ttgcaaataa ttttccttct
    16021 ggaactacga tatcaatatc tccatcagta cgattattat gtatatagga agtctcatct
    16081 aacaacttat catttacata taccttggag tcttgtattt ttacatggtc accaggaacc
    16141 ccgataactc tttttactaa atcttttttc tttccatttt cctctgttaa gtcggtttta
    16201 aatactatta tatctttgta ttttggctct cctaccttgt acgcaattct gttaactatc
    16261 aaataatcac gttcaactaa tgtaggatac attgattctc ctttgactat tgttggcact
    16321 ataaaacgag ttattgcaaa tgccaaaaca agagctatga caatcacttt tatccattct
    16381 acaacttctt ttttaactgc ttcacccact aaaatcgtct cctctgtgtt aaatattaag
    16441 tcaatctaca gcaaaataat ctaccataaa cctacaatat aaatattata cttctttttt
    16501 ctaatagttt aaaatacttt tctaagacct ttaggataat gattcttaat tacaccagaa
    16561 gattcttttc cccaacctaa aggtattcct tcaaccgaaa ccaaaaccca tcctctacta
    16621 tcattagaat tcacaacatc cccttttaaa tatttaagaa ttgattcact ctgtacactg
    16681 aagttttcaa cattttttac atcttcaact tttaagtaat gagatagtgc atgagaaggc
    16741 tcaaatctat tcttctttaa aacccctaaa tgcaaaccgt atctcaatac ttttagtttt
    16801 ttcgtatctg gatatatttc aggaagtagg tacaaatttt ctcctcttaa ataaaattta
    16861 ttttttttat tactataaaa atcaaccttt aaaaatttct tttcaaactc cctataatcc
    16921 tttatttctt tatctaaatt ttttattttt aattctttga cattacattc ttcttcttct
    16981 aattttttta ttttggcaac aaaatgacct tctcccttta tcttatgagg ccataatctt
    17041 tccatttcaa taagttctgc atgtggatat tcactgataa actcatttat aacatgctca
    17101 ttttcctccc ttgaaaaagt acaagttgag taaattaaaa tgccatcctt ctttaacatt
    17161 ttatatccat ctctgataat ctctttttgg atggattgac attctactac ctttgcataa
    17221 ctccaatctg atatggcaac ctcatccttc ctaaacatac cttgcccaga acaaggtgca
    17281 tctataataa ccttatcaaa atacccatta aacgtctttc ttaagctatt agaatcggtg
    17341 tttgttataa tacaatttct cgctccaaat cgctctaaat tttcccctag agccttaatt
    17401 ctactagcat taatttcatt agaaaccaat aaacctgtat cgtttagctt agatagtata
    17461 tatgtagatt ttccaccagg agcagcacac atatcgagaa ctttttcacc ctctttaata
    17521 tctgcctttg gtattacact cattgcagaa ggctcttgca aatagtatgc tccagcctca
    17581 tgcagtggat ttctaccagg tctgtcaatt ttatcatcat aataaaaacc ttcttctgcc
    17641 catggtattt gattcaaatc aaacaactcc aaatcaaata attttttctt gtcaattttt
    17701 aaagtattta ttctaagccc agtagtctta ctttcctcat aactttttat aaaatcatca
    17761 tattcatctt ttagtatttc ttcaatatct tctaaaaatt cctttggtaa ttctgtcaaa
    17821 tctataatcc cccttcaatc tgctttactt gtgtgtcatt tattatactt taattattta
    17881 tgtctttcct ttaaatttta tttcttcttc tttttcctaa gattaccgaa aaacactttt
    17941 ttagagtgat tcatatattt ctcaagttta tcaagattta tcttccacaa aattattaca
    18001 taaactataa gtaatataat agcccatcta tattctatca tcaatatgaa atcaaaaact
    18061 ccatgtaata aaattggaat taacactgcc ataaacaaat actcacgtct tttattttta
    18121 tttccctcaa atttatactt agaaatatag tagcccatag taattgcaaa cattacatga
    18181 gctggtatag agataactgc cctattaata ccaacttgca gtgctagatt tctactttca
    18241 gaaaaaatat aaaccatatt ttcaattgtt gcaaatccta aagctaaaaa tacagagtaa
    18301 ataataccat ctaacttttc agtaaagtgt ttttctttaa ttagggcagg aatcagtatc
    18361 agagctttta caccttcttc cacaagtcct gcaactacaa atgatacata tattagttct
    18421 gaataccctt caaatacatt aaacttcatc agtaaatttt ctaaaagtat aattataaca
    18481 cttagaaaag cacctattaa aaaaaattta attagatgga ttaggggttc tctacaatat
    18541 ctatctttag accttatcca aaacatccct atcaatatag gaactattgc taataaaaat
    18601 aaatctagct tcatagatta ttttcctttc aaaatttttg atttatttat gatttatatc
    18661 atctacttat ttttagctta tttgtgtttt aaatacatac taaaatatac attaaattat
    18721 tttaaattat ttaaatacaa atatactcaa atactcaaaa aaatttaaat ttatatctat
    18781 attatttaac aaatttcaag ctatattcat atcttgaaat ataagggaac taaattcatt
    18841 taaagaaagg gtgatttgat gcaagatggt ttcttaacag taagcataat tgatgctact
    18901 aacaatagac ctattcaaaa tgcagtagta aacatatatt caatgtctaa tggtagccaa
    18961 agctcatcaa ctttatacca aaacctaaga agtaatgaat ctggtcaagt gactggttta
    19021 gtattaccag caccagatgt agattactct ctacagccat ctgatgttag accttatagc
    19081 cagtatatag tggaagccat agcagatgga tatgagacag ttgtcataga aggaacgcag
    19141 ttgttagcta caattgtagc aagacaagga gttcccatgt ctcctagaac aagaagtaag
    19201 cgttctttct caagacaaag tgagttgatt tttgacatag gagaacatac tctatatggt
    19261 acttatcctc ctaagattcc agaaagtaac ttaaaaccat taccacctcc tactggtttc
    19321 gttgtattag ataaccctgt agtgcctgaa tttatagtag ttcatgatgg tttgccagaa
    19381 gattcatcag ctccaaacta ttggattcca tttaaagagt acattaaaaa catagcgtca
    19441 tctgaaatat attcaacttg gcctgaacag acaatctatg caaatgtaat agctataata
    19501 tcatttactt taaatagagt ctttactgaa tggtatagaa ataaaggata taactttaca
    19561 ataacttcaa caacagcata cgaccataag tttataaata atagaaactt atttgaacca
    19621 attaacgtag ttgtagatgc tatttttaat acttttataa aaagacctcc tacatcaaga
    19681 cagccactat tagcacaata ttgtgatgga caaaaatctc aatgtcctga ccaaatgact
    19741 caatggggca gtaaagactt aggtgaccaa ggatatgact atgagagtat cctaagatat
    19801 ttctatggag atgagatagt atttgaaaga gcacctatag taagtggtgt accagtgtca
    19861 ttccctggta ctacactaca agttggttct tctgggcagt atgttagaac catacaaaat
    19921 cagttaaatg ctatatctaa ttcttatcca gctgtaccaa aagttataga agatggtatc
    19981 tatggagcag atacagaaaa cgctgttaag atattccaag gaatctttgg tttacctcaa
    20041 agcggagtag tagattttaa aacatggtat gaaatatcca gagtttatgt agctacaact
    20101 agaatagctt ctttaaatcc tttaatttaa agcttgattt agaacataaa ctcaaattat
    20161 tgaataaaat tattaattta aaataaaaat ggctgttatg aactaatata taccataagt
    20221 atttttactt ataagtattg tagtcttaac agccattttt tagttataac ttgttttttt
    20281 agaatcttaa aactttaaat gggggatttt aagcttctta aaaacagtgc ttagcaactt
    20341 agatttcttt aaaatattat atttattttt aagtttaata aaatgctatt ctaacgaaaa
    20401 gcttactttt tatttaaaat ctcacttatt atttaaaatg ctacttctca cttagaatat
    20461 tactccttat tatttaaaac actatctatc acttagaata ttccttctta tctaaattat
    20521 tatttattat aaatataaat aatattaatt taaaaagtta ttcataattt aaataatact
    20581 attatcttca tcagtgaacc taaactgcaa ctttagactt attagctaaa gccaatatta
    20641 gacctaaagc tatagatgca aatgcagaag caattactct atactcagca gggaataaga
    20701 atacaattgt atgacatggt atccagaaaa atggtatagt ttttaaaaca ctaaaaccaa
    20761 ggtaagcatt ccagtccaca atatttacca catctttaag ttttacctta atcccctttc
    20821 caacctcata ttttttatct ataaaacagt ccataacctt atggaataaa aatacagttg
    20881 gtgacattag tatattcata gttgcactct taaatagagc atttgcaaaa gctattccct
    20941 caaatggaag cataccatcc acttgtgctt gacctacacc tgatgagtag attgacattc
    21001 catatgtggt aactacacct attattcccc aaactattgc tctataaaat actcctactg
    21061 gtattttcca atccttatac aaaattctag caccaagtaa atctcccatt gtagctaata
    21121 cagcaaactt taaaaaaccc ccaatatatg gatgtgcacc tgttgcttcc ataaatactt
    21181 ctctactact tggtattgct aagacagcaa taatacaaat aagaactcca ctccatataa
    21241 aatcgccttt tttcatattt ataaatacta tttaatatat aaatagttct cctttctatt
    21301 aaagatttat ttaatttaca atctatctac aattatttat taatcactta ttattagata
    21361 ttcattttcc atatttaaat ttattctatc cctttatcta tttattttct tactactcta
    21421 tccaccatta tctatatatt tattttacga ttactctttc accctaaccc tttaattatc
    21481 tatttttttc tgatattctt atctaccatc atccatatat ttattttacg attactcttt
    21541 caccctaacc ctttaattat ctattttttc tgatattctt atctaccatt atctatatat
    21601 ttattttacg attactcttt caccctaacc ctttaattat ctattttttc tgatattctt
    21661 atctaccatt atctatatat ttattttacg attactcttt caccctaacc ctttaactat
    21721 ctattttttt ctggtattct tatctactat tatccgtata tttattttat gattactctt
    21781 ttaacctacc ccctatactt tatagtaata tgtttttaac ctttttcatt attcccaata
    21841 tgctttataa ctacaaatac tctcccccct taaaaataat aataaaatta atcaataaat
    21901 ttataatcat attattactc tatgtattaa gcaattacta tgccaataaa ttttgatttt
    21961 tttaaacaaa tcttaaaaat cctaaaatgc taattttctt taacttttaa tgaatctaat
    22021 agataatatt taattttcgt tatatttttc agaatgtttc aattattatt tttaagaaaa
    22081 aaaaataatg ttaacatttc ttaacataca ttaaaaaatg ttaacattat aaatttggtt
    22141 taatactttt actttgactc gatttacttt tattctactt cttactttat ttttaactta
    22201 gactttattt ttttattact tatttgagtc ttatttattt tattctcact ccatatgttc
    22261 aattacattt gtctaaattc tttgatactt ttattacata attttaacaa gcttaagtgt
    22321 tatttgggta gtgcagttga taattattta aataatcatc aactgcatgt ttatatcatt
    22381 acagtagctt aatgtattta atcatactta cttaggattt tgaaatatct tagagattat
    22441 atttaacatt agtcaattgc tgcataattg taagcaattg aaatttgaga cccatcttca
    22501 ttttctatag tgataggctt cataattttt aatccttcag tttttatctt ttctaattct
    22561 tgttccattt tcttaattgt ttcctcaagg tctttttgac ttacatcttt gactgcatta
    22621 gggtctttag catagtcttt taattcttga atatgtttag catactcttc ataagtataa
    22681 tgctcaacac catacttttc caattcagta gggtcagtta ttcctgattt tattagagat
    22741 tcaagtttag gtaaagcaat attagatgaa tcatttccat ttgcaaatac tgctccagtt
    22801 cctcctagta ccattgcaga taccatcatt gcacttataa gggatttttt tattttcata
    22861 accaatcttc ctttcttaga gatttatttg ggtagtgtag tttaaaatga ctattgcaat
    22921 agttatcaac cacatcttta gactaccata gtagtcatat ttgtgtcaag tctttttaaa
    22981 aaacttttca ataaaaaata ctatctcaaa acaaaattaa ttattttgag atagtatttt
    23041 aattctaaat cttttatatt actaagattt atggttactc tatccatgtt ctatattgtt
    23101 ctttattaac tgctaacaaa ttcccttttc ttgatatgac aaagcgatta tcattatagt
    23161 tactttgctc aattgaaact tctcctgaat cagtataaag tacatcctta ctattactag
    23221 atttatttac atacgtttct tcactattct cagaattagt tactttgctc atagatgatt
    23281 cttcatgctc tctaaattca attacagata cttttgccgt actaaaatga gtctctccat
    23341 cacttttagc tttactaaca agaatatcag attctacttt gggagaatat aaatcagttg
    23401 atttactact tattgaaaat ccacttttat cactttgttc attttttgtt aaaccaaaag
    23461 attcaacctc attaatctct ttattttctg ttgcaaaaac aagacctgtc ccacaaacta
    23521 atacagttga aactaaaaaa gtaacataag ttgatttttt aaatttcata atattaacta
    23581 ttctcttttc tatttttgtc tttccaaatc cactacatat tgtcattgaa aatggattat
    23641 tctcctctgc tagacttatt agtgtggttg cataatcagc cctatattct tcaccaagta
    23701 tactcataac cttttcatca caactaaatt ctatgtcttt atttagtaaa aaaaacatca
    23761 cccaaactaa gggattaaac caatggacaa caagagctac aagcataaat aactttaaca
    23821 gattatcaaa gctattaata tgaaccattt catgagttaa aacaaagtct aaagtttgat
    23881 tattagcata attcatttgc tttggcaaaa taattcgtgg ttttaaaata ccagatgtaa
    23941 gtggtgtcct agtaaattca gatatgcaaa caataaatct tctaaaacgg ctattcttac
    24001 acatccattt tttaatgaac tcatgatttt ttatatgaat tgaagtttta aaaagattaa
    24061 ttattttaaa atatctaaag cataaaagta tgctaaacat aatagtaact ataaaagaca
    24121 aaatgcccaa catttccaac atcataatat tttcaatatt agacattatt tcaaattcgt
    24181 cagaattgtt tttacctgta gagtcactag ctttcttaag agtataattt tctgttgatg
    24241 tattacccaa ttctacatca aaagtcgatt caattatact ataaatacta aaaccagaat
    24301 ttaaacttac tggtattaga agtttaaata aaacaatcaa ccacaataat acaaatacct
    24361 ttttaggtaa ttttttaaat aaacatgctc ttataaaaat aactattaaa agtaatactc
    24421 cagaagtaaa actcatttct aacaatttaa tgaacataaa tcttacctca ctttaatttt
    24481 tcaacaattt gtttgagttt tgtaatctca tcacttgaaa gattttcttt attaataaaa
    24541 gctgaaagaa atttttctga agaccctcca aacattttat taattaaagt ttctgtttcc
    24601 tgtttttgta cttcctcttt gcttattaaa gctttacaaa caaaatttgg ctcaattctc
    24661 tctattgcac cttttgacac taattttttt ataacggtat acgtagtgtt tctattccat
    24721 cctgtttctt cttttaaaat ttttactaac tctccagcct tgctttctcc tctctcccat
    24781 agaacttcca ttactttaag ttctgaatca aataatttta tctccatata aaatcgctcc
    24841 tcaaatatag ttatcacaat agtcattact ataataaaaa actatcatag tagtctatac
    24901 tatgtcaatc atttattttt taataataaa aactgtcttt ttaaaaaatt cttataaaag
    24961 acagttttat caatgttata ctttaatgtt taattaaagc catattttat ttaaatgtat
    25021 aactatctat cttagtacat agtataagat ttttctttat ctaatagtat atcctctaca
    25081 tctgggtttt cttttactaa ttgtctataa aaattacaat tagtaacacc tacatatgga
    25141 attagccata gtagacctat tccaagagta gctattgaaa gtatatacca tcctataaaa
    25201 ctaaagttta gtacaaataa tttaagtaca tttcctttca tcatatctaa actagcaccc
    25261 attgatttaa atacacccat attatccttg tcttcacaaa ttaagaaagt agcttgagaa
    25321 acatataata gcaatatata aaccggtaac ataagaacaa gtattataag aactagagtt
    25381 attccagtag aaataatagt ccctattcca acattatcac ttgataaata ttcaattgct
    25441 ccactagtaa gtaaaactcc aaatgataaa aacgctccta taattgtgat tataaaagaa
    25501 taaatataaa caataattga ttcaaataaa taaaaaccaa aacttcttaa ataaattctc
    25561 ccacttacaa agatatctcc tatcttgact ttttcatctt tagtaatttt caagaacata
    25621 catgtaaatc ctgctgaaac gcaaaaagct attacagcca ctacaatagt agtcaatggt
    25681 tcaaaaggta atcctacaat tgatattaat actatcaatg caatatatac tgccatagaa
    25741 attgcacata ttccccagtt tccagataac tgagctttag atactcgttt taattcttgc
    25801 cttgatacca taaaaaacac ccctttcatt ttataaaaaa acttttaaaa atataaataa
    25861 tcttttaacg tataatatta atatatcata ttttcgacta tataagatac aattattcac
    25921 catgttttat caagatatgc cataattgta ttactagttt tatatagtca acattaccaa
    25981 atacatcaaa taaatttgat taattattca acaagtaata aaataatttc tattaattgt
    26041 actttattta gtaaacaaat tatttaataa aa
//
LOCUS       DAMJWO010000062        26005 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.063, whole genome shotgun sequence.
ACCESSION   DAMJWO010000062 DAMJWO010000000
VERSION     DAMJWO010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26005
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.063"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            221..3769
                     /locus_tag="PC366_002552"
     CDS             221..3769
                     /locus_tag="PC366_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDF2578053.1"
                     /translation="MMNRLKPRILGISILFIIIIILTCGAVFKFKFKLDNKLKETTHT
                     YLSEFTEHNIINLKTRLSGQFDMLESIANFIGNLNNINNEMVIALMDSDVKRSSLIRM
                     TISTLDGECYSNDGITHNVQDRDYFKKAKNGEKNISEPLKSIVNNKEIIVLSTPVYKS
                     GKIVGVLSGIYDSKKLNELLGLSAFDEKADVFVAKKNGDIVAQKTNKNRKTISCIFQL
                     FDKDNCDEDDCLKTIKENMKNDKSGYFNYNLDNEKFMLNYQPLGVNDWYVFSVVPNKI
                     VSIQSENISYDVYIFALEILLVILIFIIYIACIINNNTKIIINEKEKFKVLTDNILGG
                     VKTCLKDEYMTMTYVSQGFLELTGYSCEDLNKIFKNRFKDMIYKDDLDKFNCIILNQL
                     EKQDKIEVEYRIVRKDGSIIWILERSKSINDNKGSECIQGVLTDITELKKIQEELDSK
                     RFEIQAINDSIVGGIVITEINDDFDSIYLNEGYLNMIGYTRKQLEDELNNKLIKLIFK
                     DDRTELINSINKQLKLSDTFASEQRVEKRDGTIIWILLKGRKIIYDNGKSVLCCVIVD
                     ITSAKLLEQELKKSEERHEIILKQTQNIIIEWDIEKDKMNISPNWYNKFKYDPITENA
                     TKNIIKSVDIYHDDMDKFISLIKLTSQGSEYEECEIRLRTRDTIYAWFSIKATTLFDN
                     NGKPYKVVGSLTDIDESKREAEKLKERAEKDPLTDLYNKKASQSLIEEYITLDKKRKG
                     ALMIIDIDNFKGINDNLGHLYGDAVLSEIANDLINLFRATDIVGRIGGDEFIVFIKDI
                     SETRDIINKAEELVKTFERSFLGKGRNYKISLSVGIAKFPQDGMDYMTLFRNADMALY
                     SAKGKGKNCYTLYDKKIDKVQYITNTRNAGDSDNVEMSFKEHITNYIFDILYESSDIE
                     VAVNLILSIVGKHFNVSRMYIFENSDDNRVCKNTFEWCNEGVTSEINNLKNICYKDLG
                     NYLLNFNADGLFYCNDIENLGSDVKKVLKPQGIRSILQCKILEGNEFRGFIGFDECSY
                     NRMWTNDEVNTLTFISKTLSMFLLKMRIQSKLEESLTIQKSVMDNMDIWAYVVDRNTY
                     ELLFINKKMLESASNTHVGDLCYKAIWNNQDKPCKKCPMIYLKDGDDTYKSFMRNKKF
                     EVQANITTTTLKWFDGKDACLIFGSEVTSIEAEENT"
     gene            3954..5888
                     /locus_tag="PC366_002553"
     CDS             3954..5888
                     /locus_tag="PC366_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HDF2578054.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLENAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHREKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLSREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACKKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKNEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRSNKNQQKSSTKKKKKH"
     gene            5994..6989
                     /locus_tag="PC366_002554"
     CDS             5994..6989
                     /locus_tag="PC366_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2578055.1"
                     /translation="MKKYISIILLVVVTMVVLVGCSPGKDNPKNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKEGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     NYSNIKFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            6961..7746
                     /locus_tag="PC366_002555"
     CDS             6961..7746
                     /locus_tag="PC366_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF2578056.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIMLNSSFYIDILYSMGRCFFSFLLAMIFAIILSIVSYLNRFFRN
                     LLKPINALTRSIPTMILVVLALIWFEKDSTPFIVGFTIVFPILYDNVLGAILNIDKNL
                     LEMANVYKIRFIDKVLKIYLPAIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            7734..8432
                     /locus_tag="PC366_002556"
     CDS             7734..8432
                     /locus_tag="PC366_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578057.1"
                     /translation="MEKIKLSIENINKRYDSRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNRVGNKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTQLNKICDEYLELVGISDYKKFYPQMLSGGIRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFRNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSKELEKNEVLKLI"
     gene            8555..9028
                     /gene="ybaK"
                     /locus_tag="PC366_002557"
     CDS             8555..9028
                     /gene="ybaK"
                     /locus_tag="PC366_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HDF2578058.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKLTGYIRGGC
                     SPIGMKKLYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9225..10064
                     /locus_tag="PC366_002558"
     CDS             9225..10064
                     /locus_tag="PC366_002558"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HDF2578059.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTAINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKK
                     VVI"
     gene            10077..10625
                     /locus_tag="PC366_002559"
     CDS             10077..10625
                     /locus_tag="PC366_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HDF2578060.1"
                     /translation="MIKITTPVNEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10691..11872
                     /locus_tag="PC366_002560"
     CDS             10691..11872
                     /locus_tag="PC366_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HDF2578061.1"
                     /translation="MSKDYAKLALEMHEINKGKVSVESKVEVKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYIYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAIINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALEASIENLNYVQKEMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPTPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            12045..12308
                     /locus_tag="PC366_002561"
     CDS             12045..12308
                     /locus_tag="PC366_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2578062.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            12834..13517
                     /locus_tag="PC366_002562"
     CDS             12834..13517
                     /locus_tag="PC366_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2578063.1"
                     /translation="MSSILLVEDDLSLIYGLEFSIQKSGFSIDIARTVKEAMQMYEEK
                     NYDLLLLDVSLPDGNGFQICEKVREVSNIPIIFLTASDEEVNVVMGLDMGGDDYITKP
                     FKLNELISRIKALLRRYNVASNVNELSSNNITIKLLENRVFKGEFEVELTTAEYKLLC
                     LFMKNKNIVLTRKNILDKLWDGNGSFIDDNTLSVYVRRLRNKIEDNPENPKFLLTVRR
                     MGYKWNVIK"
     gene            13528..14769
                     /locus_tag="PC366_002563"
     CDS             13528..14769
                     /locus_tag="PC366_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2578064.1"
                     /translation="MKIFSNKDIKIFFLILISILVMFIIVGQIVVISITNNYKKTLIE
                     HDYNIAGYLYSIGVDKSKIPSAFVAHEDKYILKGKEILDTAGYGFDIDVSFTPSVKLF
                     QSKYIKTMSIYLLVFFTMIIFILYMYFFRQQSKIEEASYKIDLFMNGNINERLNTYEE
                     GSLSKLFSSIDVMSTSLNTHILKEKQSREFLKNTISDISHQLKTPLTALIMYNQILQE
                     ESHNSDVVEAFVQKSQSELERIETLIKNLLKITKIDSKTIVLNKNNVNLKNLIVKILY
                     SFETRAEKEGKVISINGSENTLLFCDYEWMSEALSNLIKNALDNTKENDKITIEWFET
                     TITTIVSVKDTGNGIHVEDIHHIFKRFYRSKFSKDNQGLGLGLPLVKSIVEQHNGTIS
                     VESKLSQGSTFTISFLKLTNM"
     gene            14841..15524
                     /locus_tag="PC366_002564"
     CDS             14841..15524
                     /locus_tag="PC366_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578065.1"
                     /translation="MDILVVNNLCKTYGNGYTKVEALKDVSFTVSKGEFVTVVGESGS
                     GKSTLLNLLGGLDTPTSGRIFIDGKEICSMKEEKQTIFRRRNIGFIFQAYNLIPELTV
                     EQNIIFPLLLDYKKPDTIYLDEVLTILGLKDRKNHLPNQLSGGQQQRVAIGRALITKP
                     SIILADEPTGNLDSKNSNDVISLLKVTAEKYNQTIIMITHNTNIASTADRILQVSDGV
                     LTDLGVNRE"
     gene            15521..17851
                     /locus_tag="PC366_002565"
     CDS             15521..17851
                     /locus_tag="PC366_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDF2578066.1"
                     /translation="MRSYLELVPQYAKVHKKKNRTTILCIIIAVCLVTAIFGLADMAI
                     QCQKIQFIKDDGNWHIVIRNIDEKFISEINSRVDIAHHGRGQVVDSGEFKSKEILIQG
                     LDEEVAKQFNLEIIRGRYPIGENETLIDEDAVKSFNLKIGDFIKIKLADGRNKNYKIV
                     GEYSSISSLRATDKHGLILSILGTQAIKKSETYDYYYITFKEKVNIRKATSDIKNTFN
                     LSDKQIGKNERLLSIIGQGDSDFSKPLYLTAGLLFVLVLVASIIMIYNSFNMSVIERV
                     KFFGLLRCLGSSKHQVKKFVVLESLILSIKAIPIGLVLGSLVTIISSIFLKYVNELFS
                     SMPILKVSFIGIAFGIIVGFLTVILSAIIPAKKASRVSPLSAVRGNLMSKEILNNGKT
                     SKVANTGSFKIETSMGLNHAFSRKKSFVLMTSSFAISIILFLGFSVLIDLMYQGLKPM
                     KPEAPHISIVDPNFKSVLTKEDINEISNIKGVKKVYSRMMTDIEATYNGKKTKSQLIS
                     YEKYQFNWAKKYLLKGEVNENKLQSENLALVEEGHGFDIGDKIYIKNRNAEKELEVGG
                     ILSSIPFEAKDKYIGNIITSENTFTNITGIKGYIIMDIQVDKDTPGDLIENIRRVVDD
                     NLEVRDKRQSNLEVKNSFYTMATFVYGFVFIIAIISMFNIINSMNISVTSRKNYYGVM
                     RAVGISNRQLRRMVIVEAGSYAMSGCLLGSILGLMLHRYMFISLVSSMFHLEWQVPFN
                     LLLITVLTMIIITLLSVRKPVKKICELDIIDSINAQ"
     gene            complement(18032..18874)
                     /locus_tag="PC366_002566"
     CDS             complement(18032..18874)
                     /locus_tag="PC366_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2578067.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVAHLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKAGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            19169..19903
                     /locus_tag="PC366_002567"
     CDS             19169..19903
                     /locus_tag="PC366_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2578068.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGSPIEYTISIFRTDKYQYEIVLSE"
     gene            19913..21046
                     /gene="nagA"
                     /locus_tag="PC366_002568"
     CDS             19913..21046
                     /gene="nagA"
                     /locus_tag="PC366_002568"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDF2578069.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAQVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYDQAKEAINLGVTNITHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GNYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLDNTNLKVNEAINLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGDVVYKNI"
     gene            21145..21894
                     /gene="nagB"
                     /locus_tag="PC366_002569"
     CDS             21145..21894
                     /gene="nagB"
                     /locus_tag="PC366_002569"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012425552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDF2578070.1"
                     /translation="MRVLVCKDYDGMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKLENTHLP
                     NGMADDIEKECLNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYNTVYGDITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPKDYKLV"
     gene            22084..22341
                     /locus_tag="PC366_002570"
     CDS             22084..22341
                     /locus_tag="PC366_002570"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578071.1"
                     /translation="MFSGILSSIIKLPIIGILPIGNIKKNTGISDSKKDGKQRRSNLG
                     ISIYQLPSFLYSLINNSVPSNKPIPPEEIKLIKMYLLKSCI"
     gene            23001..23705
                     /locus_tag="PC366_002571"
     CDS             23001..23705
                     /locus_tag="PC366_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2578072.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAVSRDELLNKIWGYDIEVETRAADDTVKRLRKKILDTNI
                     LIETVWGFGFRLKEKS"
     gene            23707..25194
                     /locus_tag="PC366_002572"
     CDS             23707..25194
                     /locus_tag="PC366_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2578073.1"
                     /translation="MNNGNDKNRIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTEIVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTREDDFLKNVDEMELIRECIQNEKLDLN
                     SDENTRISTRNKDYYISTVKITSIYGEQDKYLILFIDISKTLNLAQKINIVLISVMCF
                     AGILAIFTAVILSEKIAKPIKELCEFAKKMGQGDFKRTYFDFSDKELVELSTVMNKSA
                     EYLDKYDNEQKIFFQNASHELRTPLMSIKGYAEAIKYNVIDSKHASDIILEESDRLSD
                     MVEDLLYISKIDNITKDFELVECDLREVFSNCGARQNVRAINKGIKFIYEFDEEMVLF
                     ECDEKNISKAFMNLIENALRYAKSEIKIVCKYNQKNIVVIIEDDGIGIKKEDLPHVFE
                     RFYKGVGGNHGIGLSIVKSIVNKHGGRIYVENGKKGAKFTILFKL"
     gene            25399..>26005
                     /locus_tag="PC366_002573"
     CDS             25399..>26005
                     /locus_tag="PC366_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2578074.1"
                     /translation="MKEQLIFNITNLVTVVFEAFVIHMFLSDFLGQKEGYIKVVRYAK
                     LGFIICLGFCNLITLNPKITMPLIFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEI
                     VVTSIFVLFVKEGFEIMLENNSIRVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYW
                     LPLFLIPIFSLFLSVSIFDVSKFFSLESLKFLSLISSVGILY"
BASE COUNT        10377 a         2678 c         4526 g         8424 t
ORIGIN      
        1 tgataaatca aaaataaagt tatagttttt aatattaatt aagaatgatg aaatatgaat
       61 aaagatttta caaataaatc ttaagctatc ttatttaatt ctaatgcagg aagaaggtaa
      121 atgtatattg aaaaaatcat agaaatagaa gtaaacaact taaacaaata caaaggtttg
      181 caaaagaagt aatataatta tatacaatga ggatgtgagt atgatgaaca gactaaagcc
      241 aagaatttta ggtattagta tcttgtttat tattataatt attttaacat gtggagctgt
      301 tttcaagttt aaatttaaat tagataataa attaaaagaa accacacata catatttgtc
      361 tgagtttaca gaacacaata taattaatct caagacaaga cttagtggtc aatttgacat
      421 gcttgaatct attgctaact tcataggaaa cttgaataat ataaataatg aaatggtgat
      481 tgctttaatg gattctgatg taaagcgaag ttctttaatt agaatgacta tctctacatt
      541 agatggggaa tgttattcta atgatggaat cacccataat gttcaagata gagattattt
      601 taaaaaagct aaaaatggag aaaagaatat ttcagagcct ttaaaatcta ttgttaataa
      661 taaagaaata atagttttat ctaccccagt ttataaaagt gggaaaatag ttggtgtttt
      721 aagtggaatt tatgattcaa aaaagttaaa tgagttatta ggattatctg catttgatga
      781 aaaagcagat gtttttgttg caaagaaaaa tggagatata gttgctcaaa aaacaaataa
      841 aaatagaaag acgatatcat gtatatttca gctttttgac aaagataatt gtgatgaaga
      901 tgattgtcta aaaactataa aagaaaatat gaaaaatgat aagtctggat attttaatta
      961 taacttagat aatgaaaaat ttatgttaaa ctatcagcca cttggagtta atgattggta
     1021 tgttttttct gttgtgccaa ataaaatagt gtctattcag tcagagaata tatcttatga
     1081 tgtatatatt tttgcattag aaatactact agttatattg atttttataa tatatatagc
     1141 atgtattata aataataaca ccaaaattat tataaatgaa aaagaaaaat ttaaagtact
     1201 cactgataat atattaggag gggttaaaac ctgtttaaaa gatgaatata tgactatgac
     1261 atatgtaagt caggggtttt tagagcttac aggttactct tgtgaagatt taaataaaat
     1321 atttaaaaat agatttaaag acatgattta taaagatgat ttagacaagt ttaattgtat
     1381 tattctaaat caattagaaa aacaagataa aattgaagtt gaatatagaa ttgtaagaaa
     1441 agatggaagt ataatttgga ttttggagag aagtaagtct ataaatgata ataaaggaag
     1501 tgagtgtatt cagggagttt taactgatat aacagaactt aagaaaatac aagaagagtt
     1561 agattcaaaa agatttgaaa tacaggctat caatgatagt attgttggtg gaatagtgat
     1621 aactgagata aatgatgatt ttgatagtat atatttaaat gaaggttatt taaatatgat
     1681 tggatataca cgcaaacaac tggaagatga gctaaataat aaattaatca aacttatttt
     1741 taaagatgat agaacagaat taattaatag tataaacaaa caactcaaat taagtgatac
     1801 atttgcatct gaacaaagag ttgaaaaaag ggatggtact attatatgga ttttattaaa
     1861 aggaagaaag ataatttatg ataatggaaa atctgtactt tgttgtgtta ttgtagatat
     1921 cacttctgct aaattattag agcaagaact taaaaagagt gaagaacgtc atgaaatcat
     1981 tctaaagcag acgcaaaata tcataataga atgggatata gaaaaagata aaatgaatat
     2041 atcacctaat tggtataata agtttaaata tgaccctata actgaaaacg caacaaaaaa
     2101 tataattaaa tcagtagata tatatcatga tgatatggat aagtttattt cattaattaa
     2161 acttacttca caaggtagtg agtatgaaga gtgtgaaatt agacttagaa ctagagatac
     2221 tatttacgct tggtttagta taaaggcaac aactttattt gataataatg gtaaacctta
     2281 taaagtagta ggaagtttga ctgatattga tgaatcaaaa cgagaagctg aaaagttgaa
     2341 agaaagggca gaaaaagacc ctcttacaga tttgtataat aaaaaagcat cacaatcact
     2401 tatagaagag tacataacat tggataaaaa aagaaaaggt gctttaatga ttattgatat
     2461 tgataacttt aaaggaataa atgataattt aggacattta tatggggatg ctgtattaag
     2521 tgaaattgca aatgacctaa taaatctatt tagagcaacc gatatagtag gcagaattgg
     2581 tggagatgag tttattgtat ttataaaaga tatttctgaa acaagagata ttataaataa
     2641 agcagaagaa ttggtaaaaa catttgaaag gtctttttta ggtaaaggac gaaattataa
     2701 aatatcatta agtgtaggaa ttgctaagtt tccacaagat ggtatggact atatgacact
     2761 atttagaaat gcggatatgg ctctttactc agccaaaggg aagggtaaga attgttatac
     2821 attgtatgat aaaaaaattg ataaagtcca atatataact aatacaagaa atgcaggaga
     2881 tagtgataat gtagagatgt cttttaaaga acatatcaca aattatatat ttgatatact
     2941 atatgaatca agtgatatag aagtggcagt aaatttaatt ctaagtattg taggtaaaca
     3001 ctttaatgtg agtcgcatgt atatatttga aaattcagat gataatcgag tatgtaaaaa
     3061 tacatttgaa tggtgtaacg aaggtgtaac ctcggaaatt aataatctta aaaatatttg
     3121 ttacaaggat ttaggcaact atcttttaaa ttttaatgca gatgggttat tttattgtaa
     3181 tgatattgaa aatttaggta gtgatgtgaa aaaagtactt aagccacaag gcatacgttc
     3241 aatattacaa tgtaaaattt tagagggcaa tgaatttaga gggttcatag gatttgatga
     3301 atgttcatat aatcgtatgt ggactaatga tgaagtgaac actttgacat ttatatctaa
     3361 aacgctcagt atgtttttat taaaaatgcg tattcagagt aagctagaag agtctttaac
     3421 aattcaaaaa tctgtgatgg ataatatgga tatatgggca tatgttgttg acaggaatac
     3481 ctatgaatta ttatttatca ataaaaaaat gcttgagtca gcatcaaaca ctcatgtagg
     3541 tgatttatgt tataaagcga tatggaataa tcaagataaa ccttgtaaaa aatgccctat
     3601 gatatattta aaagatggtg atgatactta taaatcattt atgcgcaata aaaagtttga
     3661 ggtacaggca aatataacta caactacttt gaaatggttt gatgggaaag atgcatgttt
     3721 aatatttgga agtgaagtaa ctagtattga agctgaagaa aatacttaaa atactgtgtt
     3781 atatatatac ttaaaatcgc aatttgaatt tattagactt aaaatgtcta tataaatcat
     3841 ttaagttgtg gttttaagta ttttttatga tataattaag cgttaagaac aaaattaaaa
     3901 gatacttttg tataaaaaaa tatttgttaa atatatattg agcaggtgat aatatggaaa
     3961 ataagttttt accaataagc aaacaagata tgatagatag aggatgggaa gaattagatt
     4021 ttgttctagt tacaggagat gcttatgtgg accatcatag ttttggaaca gcaataatat
     4081 ctagagtttt agaaaatgct gggtataaag ttggaataat agctcaacca gactggagaa
     4141 ctacagatga ttttatgaag ctaggaaaac cgagacttgc atttctagtt aatgcaggaa
     4201 atatggattc aatggtcaat cattattctg taagtaaaaa gcatagagaa aaggatatgt
     4261 attctccagg tgggaaaatg ggttatagac cagatagagc tactatagta tattgcaata
     4321 aaataagaga agcatacagt gatgttgcaa tagtaatagg tggaattgaa gcgagtttaa
     4381 gaagatttgc acactatgat tattggagtg ataaggttag aaagtctatg ttaatagata
     4441 gtggagcaga tttattagtt tatggtatga gtgaaaagca gattgtagaa gtagccaatg
     4501 cacttaatga tggatatgac ccaaaatata ttagacatat tgatgggaca tgctatattt
     4561 cagatacatt ggaagaaata tatgataaat atatattaat tccatcatat aaagaaattt
     4621 gtgaagataa aatgaagtat gtagaagctt ttaaaattca atatgatgag caagacccat
     4681 ttagaggtaa tataattgtt caacctcatg gaagtaagta tctggttcaa aataagccag
     4741 aaaaaccact tagtagagaa gaactagatg aagtatatgg attaccatat cagaagacat
     4801 accatcctgt gtatgaaaaa tttggaggaa taccagctat agaagaagta aaatttagta
     4861 tagtaagttc aagaggctgt tttggtagtt gttcattttg tgcaataaca tttcatcaag
     4921 gtagagcagt gcaaagtaga agtgaaaaat caattattga tgaagcaata ggaataacaa
     4981 atttagatga ttttaaaggg tatatacatg atgttggagg tccaacagct aattttagaa
     5041 gaccagcatg taaaaaacaa attactaaag gtgcttgtaa aaatagacaa tgcttatctc
     5101 catcaccatg taaaaattta gatgcagacc acagtgaata cttacattta cttagagctg
     5161 taagaaaatt acctaaaata aaaaaggtgt ttgtgcgttc tggaattaga tacgattatg
     5221 taatggcaga taagaacaat aaatttctta gagagttgat agagcatcat gtaagtggtc
     5281 agttaaaggt agccccagaa catatatcag aagaagtttt aaagtatatg caaaaaccag
     5341 caggaaaaac ttatgataaa tttagacaga agttttttgc tataaatgaa gaattaggta
     5401 aaaagcaata tttgataccc tatttaatgt ctagtcaccc tggttctacc ttaaatagcg
     5461 ctatagagtt agcagagtat ttaagagata ctcactacca accagagcag gttcaggatt
     5521 tttatccaac tccagggact ctatctacaa ccatgtttta tacaggtatt gacccgctta
     5581 caatgaagcc agtttatgtt cctaaatcaa aacgtgacaa ggcaatgcaa agggctttat
     5641 tacaatatag agcacctaga aattatgatt tggtatactc tgcgttagtt gaagcaggaa
     5701 gagaagactt aattggtttt ggacatagat gtcttataaa gccaaaaaat gaaaagcctt
     5761 attttaatag aaataattct aaaaaaaatg tatctaaagg aacaaataaa aacaaaaaaa
     5821 ctaatacaaa taacagaagt aataaaaatc aacaaaaaag ttcaactaaa aaaaagaaaa
     5881 aacattaaag tataaataaa aatacttaaa aaagaaggat tattcgataa attaacagaa
     5941 attagtataa ataaatataa ttattttaat gacgttacct ttgggaggaa gagatgaaaa
     6001 agtatatttc tataatatta ttagtggtgg tgactatggt tgttttggta ggatgttcac
     6061 caggaaaaga taaccctaaa aataaggagc tatcagttgt caaacaagta aaagtagctg
     6121 ttccagatgg actaccagca gtggcaatag ctaaacttgc aaatgaaaat ccagagatta
     6181 aagaaggata tgaaacagtg tatagcattg aaaagacacc tgaggcgatt tccactagag
     6241 tgatgaaaaa agatgcagat atagctatag ttccttcaaa catggctgca atagcgtata
     6301 ataaaacttc atcatataat attgttggaa ctgtaggaat gggttcactt tatttggtgt
     6361 caacagaaaa tataaaagat tattctgatt tagttggtaa agaagttgga tgtactggaa
     6421 aaggacttac tccagacata actataaaaa gtcttttgtt acaaaaggat ataaattatt
     6481 caaatataaa atttaattat gtaaattcag caagtgaact ggtaccatta ttggctactg
     6541 gtaaagttaa gacaggtatt gttccagaac ctgcacttag tgctttgatg tctaaaaatc
     6601 cagacataaa aattataaaa agtttaaatg actcatggaa ggaagtaagt ggttcaaaag
     6661 acggttatcc tcaatctact ttaattgtaa agtctgaatt tttaagagat aataaagatt
     6721 ttgttgattc ttttgtaggt caattatcaa atagtataga ttgggcaaac aaaaatcctg
     6781 aagaattagg tgcatattct gaaaaaataa aaatatctac tgaatcaaag ataataggaa
     6841 aatctcttga aagagctaat ttaaaatata ttccagttaa ggacatgatt aaagattata
     6901 aaaattacta tgagaaatta gctaattttg atgataagac attaggaggc aaagtaccag
     6961 atgaagcaat atactttgtt gagaaataaa aaaaataaag aacaatttat agataaaatg
     7021 gaggtaacac tttcttgtgt tatcctctta tttttatggc aaattattgc tttaaaaatt
     7081 gataatgata tttttttacc aacagtaggt caagtattta atagtataaa agagattatg
     7141 ctaaattcta gtttctatat agatatactt tactctatgg ggagatgttt ttttagtttt
     7201 ttactggcta tgatttttgc cattatactt tcaatagtat cttatttaaa tagatttttt
     7261 agaaacttat taaagccaat caatgctttg acacgttcaa taccaactat gatattggta
     7321 gtacttgcac ttatttggtt tgaaaaggat agtacccctt ttatagttgg atttactata
     7381 gtttttccta tattgtatga taacgttttg ggcgctatat tgaatataga caagaactta
     7441 ttagaaatgg ctaatgtgta taaaataagg tttatagata aggtgttaaa aatttattta
     7501 ccagccataa aatttcaaat tatatctata ctagtatcaa cattctcttt aagtttgaaa
     7561 gttgctatag caggagaggt atatagtcaa cctacatatg gtattggaac tatgatacag
     7621 actgaaaaaa ttaactttaa tacatctgga atatttgcat ggataattat tgttctttta
     7681 atatctgcta ttttacaaat agcccaaaag tttttagcaa ggagagcttt tttatggaaa
     7741 agataaagtt gagtattgaa aatataaata aaagatatga tagtcgtatt atatttagag
     7801 attttaatat tgatttttat gtaaatgagg taaattgtat ccttggaaaa tctggttgtg
     7861 gaaaaactac actcttgaac ataataagtg ggattattaa aaatgacacc aacaatctaa
     7921 atatcaaaga aaatttaaat agagtaggaa ataagcttga agctagttac atatttcaag
     7981 atgatagact tatagactgg ttaacagtag aagaaaatat aaagatagtt gtaaataaat
     8041 actataataa aactcaatta aataaaattt gtgatgaata cttggaattg gttggaatta
     8101 gtgattataa aaaattctat cctcagatgc ttagtggagg tattagacaa agagtaaata
     8161 ttgctagagc ttttatatat ccatcaaaaa acattataat ggatgaacct tttaaatcta
     8221 ttgatgcaaa gaatacacag cttataatgg ataatttcag aaatatatta agaaaagaaa
     8281 agagaactgt attatttgta actcataata ttgaggaagc attgttttta gcagatagga
     8341 tatttatttt aggagactct ccaattagaa taaaaaaaat attaaaaaat tctaaggaat
     8401 tggaaaaaaa tgaagttttg aagttgatat agagttataa taatactgtc gttttaaaat
     8461 atatttggtt aaaatctata agactatatt aaaatagtac agaatattca aaactgtgta
     8521 taatgttcgt attttataaa aaggaagtga atgtatggtt aagactaatg ctatgagaat
     8581 attagattca aataagattg attataaagt aatgtcttat gaagtgaaaa gtgaacatgt
     8641 ggatggtgtt gaggtggcac atgatatagg aagagatgta aatgaagtgt ataagacatt
     8701 agtaactcaa ggagttagta agaatatata tgtatatgta ataccagtac atgaaaactt
     8761 agacttaaaa aaggctgcaa aagtagctaa agagaaaagt gtagagatga ttcatgtaaa
     8821 agatataaat aagcttacag gttatattag aggcggatgt tctcctatag gtatgaaaaa
     8881 gctttataaa acttttgtaa atgaaagtgc aaagaattta gatacaatta ttgtgagtgc
     8941 aggaaaaata ggatatcaaa tagaactatc tccatttgat ttacaaagac ttataaaagt
     9001 agaatttgta gatgtaataa aaaaataaga attacatata aaatatagag cttatattct
     9061 taataatagg tgttgtaata ttaataaaat gaataataat tttaaaataa atattcagtt
     9121 acttatgtgt aattggtata aaaatattga gaaattttaa aaacaatggt aaagtgtaag
     9181 tataatcacg aatatttttt ataaagtaat ggagggatgt tcgcttgaga aaaataaaat
     9241 ctgaacaaat cgtcgagcag gtaaaaaaac tttgtataga agcgagccta tatttaggag
     9301 aagatgtttt aagttgtata aaagaaaaag cgaaaagcga aaagagtgaa gttggaaaaa
     9361 atatattgaa tatattagtt gaaaatgctg aaatagctaa agaaaaaaat ataccaatat
     9421 gccaagatac tggtatggct gtattttttg ttgaaatagg acaagaagtt ttaattgaag
     9481 gagacacact tactgatgct ataaatgagg gagtaagaca agggtatgaa gaaggctact
     9541 taagaaaatc tgttgtaagt ccaattaaca gagtaaatac aaaagataat acacctgctg
     9601 ttattcatta tgatatggta aaaggtgata aaattaaaat agaatttgca gctaagggat
     9661 ttggaagcga aaatatgagt aagatgaaaa tgttaaagcc atcagatgga ttggaaggaa
     9721 ttaaaaaatt cataatagat acagtttcag aagctggacc taacccatgc cctcctatgg
     9781 taattggagt tggtataggt gggactgtgg acaaatgtgc tcaaatagct aaaaaggcac
     9841 tttttagaga actaggtgaa tttaataagg acgaaaatat agcaaaactt gaaagtgaac
     9901 tattaacagc tattaataaa cttggtatag gacctcaagg cttaggtggt actacaacag
     9961 ctttgggatt aaacatagag acttttccta cacacatagc aggtctacct gttgttgtaa
    10021 atataaactg ccatgcatca agacataaga aggtagtaat ttaggaggaa aataaaatga
    10081 taaaaataac tacacctgta aatgaaattg atatagcaaa attaaattgt ggagatacaa
    10141 ttagtttgag tggtatactt tatacagcaa gagatgctgc tcataaaaga ttgatagatt
    10201 gtataaataa aggtgaagaa ttaccatttg acgtatatgg tcaaggaata tattatgtag
    10261 gacctactcc tacaaagcca ggagaagtta taggtgctgc aggtccaacg acgagttata
    10321 gaatggatga tttgactata cctcttttag aaagaggtct tagattgatg ataggcaagg
    10381 gaaaaagaag tgatgaagtt atagaaggta tgcaaaaata cggagcagtt tatcttgctg
    10441 caataggagg agctggagcg tatatttcaa attcaataaa atcatgtgaa attattgcat
    10501 atgaagattt aggagctgaa gctataagaa agattgtagt agaagacctt aaacttacag
    10561 tagcaataga tagctatgga aataatatat atgagcaagg tcgagcaatt tatgaatgta
    10621 aataatgttt agaaataaat atgaatatca aaattaaaaa tagttgtgta tattttaagg
    10681 aggaaaattg atgtctaagg attatgcaaa attggcatta gaaatgcatg aaatcaacaa
    10741 agggaaagta agtgtagaaa gcaaggtaga agttaaaact aaggatgatt tatcaacagc
    10801 atatacacca ggggttgctg aaccttgttt aaaaatacat gaaaatcaag atgatgttta
    10861 tatatacact tctaaaggga atctagtagc agtagttagt gatggaagtg ctgtacttgg
    10921 attaggtaac attggtgctg aagcatctat acctgttatg gaaggtaaag ctatattatt
    10981 taaacaattt gcagatgtag acgcttttcc aatatgttta aagactaatg atgtagatga
    11041 gatagttaaa tctgtagagt tgatggagcc tgtatttgga ggtataaatt tggaagacat
    11101 atcttctcca agatgttttg agatagaaga gagattaaaa aaatctttaa gtatacctgt
    11161 ttttcatgat gaccaacatg ggacagcaat aatagttgca gcagccataa taaactcaat
    11221 aaagttaatt gaaaataaaa aaatagaaga tttagaaata gttataaacg gagcaggagc
    11281 tgctggtata gccatagcaa agatactact taatatgaat gttaaaaata taatcttatg
    11341 tgatagaagt ggagcattgg aagctagtat agaaaatcta aactatgttc aaaaagaaat
    11401 gttaaaagta acaaatataa gaaatgaaaa aggaccttta aaagatatta taaaaggaaa
    11461 agatgtattt attggtgttt caggtccagg agctgttaca aaggaaatgg ttgaaagtat
    11521 gtctgagaag ccaataatat tggcaatggc aaatcctact ccagagataa tgccagaaga
    11581 agcaaaatta ggtggagcat ttataatggg aacaggtcgt tcagacttcc ctaatcaagt
    11641 caataatgta ctggcttttc ctggaatatt tagaggagca ttagatgtta aggctaaaga
    11701 gataaatgaa gaaatgaaga tagctgctgc atatgcaatt gctaatacaa taagtgatga
    11761 agaaatatgc ccagagtata tattaccaga tgtatttaat aagaatgtag taaaaaatgt
    11821 tgctaaggca gttaaagaag cagcgataaa aactaaagta aatagaatat aaatttttat
    11881 aacttattaa aaactagaaa agtataaaag actagtgaaa ttatgtacag tgggatgatt
    11941 ttattagtct ttttatttta aatatgacac aataatgtca tattaagctt gatataattt
    12001 taatatggtt aggagccaaa gaaaaatata aggagtgatt taaaatggaa gaaactaaat
    12061 tttgccaatg ctgtgcaatg ccaatgggac aaactgatga attatatggg acaaataaag
    12121 atggaagtaa aagtactgat tattgtagtt attgttttaa agatggtgag tttacagctg
    12181 atataagtat ggaagagatg atagaagttt gtatccctca tatgcttcaa agtaataagg
    12241 atatgactga agatgaagca agaacaatga tgaacaattt ctttccaaca ttaaaacgct
    12301 ggaaataatt ttatgcaaaa ttagttatat gcaaaacatg aaatatggtg ttgagaataa
    12361 ggggtggtgt gctttatagc ataccacctg ttttgttact tgctagttca gttattcttg
    12421 tatgcttaaa tatgttctca tctctctttc tattttaaat tgtaaaaatc taaaatatgt
    12481 tatttatatt ctacttcttt atccatgtct ttttctacct caagtcaaat acaactacaa
    12541 aatcatcatt ttcaattcac tgtttaatag aattaacaga taaagagtta taaaattttc
    12601 tattttttat ataaaataat acaggtcaag ctgacttcta gctacttggg atagtgtata
    12661 tatttatgat agttatagga gtaataccaa tcattagact gttgatttgt gtagtctttt
    12721 gtaaaaacat ttgttttaat atattgagtt tttgaaaaag taaaattata attataataa
    12781 attaagtgta ataatgtatt agaagtaaaa ataattaaaa tagaggtgat taaatgagca
    12841 gtatattgtt agttgaagat gatttaagct tgatatatgg attagagttc tctatacaaa
    12901 aaagtggatt tagtatagac atagcaagga cagtaaaaga agctatgcaa atgtatgagg
    12961 aaaaaaatta tgacttattg cttttagatg tatccctacc tgatggtaat ggatttcaga
    13021 tttgcgaaaa agtacgagag gtttctaata tacccattat atttttgact gcttcagatg
    13081 aagaggtaaa tgtagtgatg ggtcttgata tgggtggcga cgattatata acaaaacctt
    13141 ttaaattaaa tgaattaatt tcaagaataa aagcattact tagacgttat aatgttgcaa
    13201 gtaatgtgaa tgaattaagt tcaaataata ttactattaa attacttgaa aatcgtgttt
    13261 ttaaaggtga atttgaggtg gaacttacta cagcagaata taaattattg tgcttattta
    13321 tgaaaaataa aaatattgta cttactagaa aaaacatatt ggacaagtta tgggatggaa
    13381 atggtagctt tatagatgac aatacattat cagtatatgt aagacgattg agaaataaaa
    13441 ttgaagataa tcctgaaaat cctaagtttc tattgaccgt tagaagaatg ggttataagt
    13501 ggaatgtaat taagtgaggg tattaatatg aagatatttt ctaataaaga tataaaaata
    13561 ttttttttaa ttcttatatc tattttagta atgtttatta tagtagggca aatagtggtt
    13621 ataagtataa ctaacaatta taaaaaaacg ttgatagaac atgattataa tatagctgga
    13681 tacttatata gtataggtgt tgataaatct aaaataccat cagcatttgt tgcacatgaa
    13741 gataaatata ttttaaaagg aaaagaaata ctagatacag ctggatatgg atttgatata
    13801 gatgttagct ttacaccaag tgtaaaattg tttcaaagta aatatataaa aactatgtct
    13861 atctatttat tagtattttt tactatgatt attttcatac tatatatgta tttttttagg
    13921 caacaaagta agatagaaga ggctagttat aaaattgatt tatttatgaa tggaaatata
    13981 aatgaaagac taaatacata tgaagaaggt agcttatcaa aattatttag ttcaatagat
    14041 gttatgtcga catctttaaa tacacatata ttaaaagaaa aacagagcag agaatttctt
    14101 aaaaatacaa tttcggatat atcgcatcaa ttaaaaactc cacttacagc tttaataatg
    14161 tacaatcaga tactacaaga agaaagtcat aatagtgatg tcgttgaagc ttttgtacaa
    14221 aaaagtcaaa gtgaactaga acgcattgaa acattgatta agaatttact aaagattaca
    14281 aagatagatt caaaaacaat agttctcaat aaaaataatg ttaatcttaa aaatttaatt
    14341 gtcaaaattt tgtatagctt tgaaactagg gcagaaaaag aaggaaaggt tatttctata
    14401 aatggttcag aaaatacatt gttgttctgc gattatgaat ggatgtcaga ggctttaagt
    14461 aatcttataa agaatgcatt agataataca aaagagaatg ataaaataac gatagagtgg
    14521 tttgagacga ctataaccac cattgtttca gttaaagaca ctggaaatgg aatccatgtt
    14581 gaggatattc atcatatatt taaaaggttt tatagaagta agttttcaaa agataatcaa
    14641 ggtttaggac tgggattacc actagttaaa tctattgtgg aacaacataa tggtactatt
    14701 tctgtagaaa gtaaactatc acaaggaagt acattcacca taagtttttt aaagcttact
    14761 aatatgtaag ataaaataca tcttgcagta aggtatatag attattatta tattaatcaa
    14821 ttagaaaggt gagagagaaa atggatattc ttgtggttaa taatttatgt aaaacatatg
    14881 gaaatggata tacaaaagta gaggcattga aagatgtatc ctttacagtt tcaaaaggag
    14941 agtttgtgac tgtagttgga gaatctggtt caggaaagag tacactatta aatctcttag
    15001 gaggtcttga tactccaaca tcagggagaa tatttattga tggtaaagaa atatgttcaa
    15061 tgaaagagga aaaacagact atttttagac gtcgtaacat agggtttata tttcaggcat
    15121 ataaccttat accagaacta actgtggagc aaaatataat attcccattg ttattagatt
    15181 ataaaaaacc agatactatt tacttagatg aagtattgac tattttaggt cttaaagata
    15241 ggaaaaatca tcttccaaat caattatctg gtggtcaaca acagagagtt gcaattggaa
    15301 gggctttgat tacaaagcca agtattatac tggcagatga gccaacggga aatcttgaca
    15361 gtaaaaatag taatgatgta atttcacttt taaaagtgac tgcagaaaag tataatcaaa
    15421 ccattattat gataactcat aatacgaata tagcttctac agcagataga atactacagg
    15481 tttctgatgg tgtgcttaca gacctggggg tgaatagaga atgagaagct acttagaatt
    15541 agtaccacaa tatgcaaaag tacataagaa aaaaaataga actacaattt tatgtattat
    15601 tattgcagta tgcttagtta ctgctatctt tggacttgca gatatggcta tacaatgtca
    15661 aaagatacaa tttattaaag atgatggaaa ttggcacata gtaattagaa atattgatga
    15721 aaagtttata tcagaaataa atagtagagt agatatagct caccatggta gggggcaagt
    15781 cgttgacagt ggagagttta aatcaaagga gattttgata caaggtttag atgaagaagt
    15841 agcaaaacaa tttaacttag aaataataag gggtcgttat cctattgggg agaatgagac
    15901 tttaatagat gaggatgcag ttaaaagctt taatctaaaa ataggagatt ttatcaaaat
    15961 aaaattagca gatggtagaa ataaaaatta taagatagta ggtgaatatt catcaatatc
    16021 aagcttaaga gctacagata aacatggatt aatactttca atattgggta cacaagctat
    16081 taaaaaatca gaaacgtacg attattatta tattacattt aaagaaaagg ttaatattag
    16141 aaaagccact tctgatatta aaaatacctt caatttaagt gataaacaaa tcggtaaaaa
    16201 tgaaagatta ctttctatta taggtcaagg cgactctgac ttttctaaac cactgtattt
    16261 aacagcagga ttactttttg tacttgtttt agtagcaagt attatcatga tatataatag
    16321 ttttaacatg agtgtaattg agagagttaa attttttggt ctgttacgtt gtctagggtc
    16381 atcaaaacat caagttaaaa aatttgttgt tttagaaagt ttaattttaa gtataaaagc
    16441 tattccaata ggcttagtat taggaagtct tgtaactatt atatcttcta tatttcttaa
    16501 gtatgttaat gagttattca gctcaatgcc aattttaaaa gttagtttta ttggtattgc
    16561 atttggaata attgtagggt ttttaactgt aatattatca gctattattc cagcaaaaaa
    16621 agcttcccgt gtatctccac ttagcgctgt acgtgggaat ctaatgtcca aagaaatttt
    16681 aaataacggg aagacaagta aagttgcaaa tacaggaagt tttaaaattg agacttctat
    16741 gggattaaat catgcttttt caagaaagaa atcttttgta cttatgactt cttcatttgc
    16801 cattagtatt atactatttt taggttttag tgtgcttata gaccttatgt atcaaggact
    16861 taagcctatg aagccagaag ctcctcatat atctattgtt gaccctaatt ttaagtctgt
    16921 tttaactaag gaagatatta atgaaataag caatatcaaa ggagtaaaga aagtatacag
    16981 tagaatgatg acggatatag aagctacata taatgggaag aagacaaaat cacaattaat
    17041 ttcttatgaa aagtatcaat ttaattgggc aaaaaaatat ctattaaaag gagaagttaa
    17101 tgaaaataaa ctacagtcag aaaaccttgc attagtagaa gaggggcatg gatttgatat
    17161 aggagataag atatatatta aaaatagaaa tgctgaaaaa gagttagagg taggaggtat
    17221 actttcctca attccatttg aggctaaaga taaatatatt ggaaatatta taacatctga
    17281 aaatactttt acgaatataa caggtataaa gggttatata ataatggata ttcaggttga
    17341 taaagatact cctggagatt taattgaaaa tataagacgt gtagtagatg ataacttaga
    17401 ggtcagagat aaaagacaaa gtaacttaga ggttaaaaat tcgttttata ctatggcaac
    17461 atttgtatat ggatttgtgt ttattattgc gattataagc atgtttaata tcataaatag
    17521 catgaatata agtgttacaa gtagaaagaa ttactatggt gttatgcgtg cagtaggcat
    17581 atccaacaga caattaagaa gaatggtaat agtagaggca ggttcatatg caatgagtgg
    17641 ttgtttatta ggtagtatac taggattaat gttacatagg tatatgttta tatcgttagt
    17701 aagttcaatg tttcatttag agtggcaagt accttttaat ttactactta tcactgtact
    17761 aactatgata ataataactt tattatcagt aagaaaacca gtcaaaaaga tttgtgaatt
    17821 agatataata gactcaataa atgcacaata aatatagctg ttgatttaaa ttaaaaaaac
    17881 gaagtaaaaa tgaaatagaa aatatttttc atttttactt cgttttttat attataaaat
    17941 ttttgttatg ttacaaaatt tctataaaga tgatgtgaat ctaaacatta tatgacaacg
    18001 tgagcattta agttaaaata ttttaaatat actattttag ataagttcct tcttcatctt
    18061 gataaattaa tccttttttc ataagcactc caagagctcg tttaaaattt ttcttacttg
    18121 aattaaataa tatagaaata tctttagggt cagatttatc attaaatctc atatatccat
    18181 cagaaccctc taaataactt aaaatcttat tttctaaagt atcaagttca tcctttctat
    18241 ttcctctagg agaaagacca agttttccat cttcatatat ttttatgaca tgtaaatttt
    18301 caagaacatc accagctttt agttcagtaa agtactcatt atgaagtatt acaccagcat
    18361 atttattgtc tacacatatc attgcagaat tattagtttg aaatccatat acaactccag
    18421 ttacaatatc tcctacattg taagtatggt ctgttaataa atatgaatct atatctgtag
    18481 tagcagcaat tcttttgctt ttgtctaaat atatataaaa taaatatttt tcgtctctaa
    18541 atagtggata agtcttagct ttaaaaggaa ctagtatgtc tttaggaagt cccatatcta
    18601 taaaagtacc aatgtccgta ttatcaacta cttttaaatg tgctacatcc ccaaccttag
    18661 ctaaaggcgg tattaaagtt gcagcagttc tgtcatcaga atctttaaat atgaaagcat
    18721 ttacttcatc acctatgttt atttcatttt ttccgattaa tctattatga agaagtatat
    18781 cgtcttttgt gttattagtt tgtccatcca aaaaatatcc aaattcagtt tttcttttta
    18841 ctgtaagttt attaaaatca cctatgttta tcaaattaaa atcatcctct cattttatat
    18901 ttataattta gccataatat acttatgtag tagtttgtca cagtatctat attagtatta
    18961 gtgaaattta caataaataa tatagttatt tatgtatttt tcaattctct agcttcttat
    19021 atagtataaa ctccaatttc ttttttgtct ttaggtttta ctaaaatttt tacaaaataa
    19081 gttaaaaagt attgaaataa aatttctttt aaagtataat tggtatatac caaaattggt
    19141 atataccata tcgaaaagtg gtgactatat gaaaatagta aataaatcta gtaatatacc
    19201 attgcatact caattaagtt caataataag agagatgata gaaactggtg agcttaaaga
    19261 gggtgatgca ataatgccag aaagagaact ttgcaacata caaaatgtaa gtcgtatgac
    19321 agtaaataaa accattgttg gattagtcac agaaggactt ctttataggg tacaaggtaa
    19381 agggacattc gttgcaaagc aaaaaaagaa gtatcagttt tcaaatgtaa aaggttttac
    19441 tgatgttatg aaagaaaagg gagtaaacat aaaaacggat atattatcct ttgagatgga
    19501 actaccagat gatttagtta aaagaaagct tggaataagt gataatacta caaatatata
    19561 taagattgtc agacttagat atactgatgg agagccattt ggattagaaa tagtatatct
    19621 atcagaagaa atgtgtaaag gtctaacaaa agggatattg gataattctt cattatatag
    19681 ggttttaaat gaaaaatatg gctataagat acaaaaagct gaacaagtaa tggagccagt
    19741 aatactttca gatgaagaaa gtaagcttct tgaaacagat gaaggtgctt tagctcttaa
    19801 acttcataga aattcctata atagagaagg tagccctata gaatatacca tatcaatatt
    19861 tagaacagat aaatatcaat atgaaatagt attgagtgag taggtgaata atatgaaatg
    19921 tttaattaat ggaaagataa tattaaaaaa tcaaatcttg gaaaataaag tattagtatt
    19981 tgatgaaaaa ataattgata tagctgatag tgtaccaaaa gattgtgaag ttatagatgc
    20041 tgatggaaaa tatatatctc cagggcttat tgatattcat atacatggaa atatgggaaa
    20101 agatacaatg gattcgactg atgaatctat tgaaacaatt tcaaaatcaa ttatgagaca
    20161 tggagtaaca tcttttcttc caactacaat gactatggat aaagaacatg tttatgatgc
    20221 acttgaagtt attaaaaaag cccaaaatag aaagcttgaa ggggcacaag tattaggagc
    20281 acatttagaa ggacctttta taaatgagaa ttataaggga gcacaaaatg aaaaatttat
    20341 aataaattca aaatacgaat ttataaaaga atataaagat gttataaaag ttataactta
    20401 tgctccagaa aaagatattg attttgattt tactagagaa ataaaaagat gtacagatat
    20461 agttttatct attggtcata gtaatgcaaa ttatgaccaa gctaaagaag ctataaattt
    20521 aggagtaact aatataactc acatgttcaa tgcaatgact ggtttaaacc atagagaccc
    20581 aggcgttgtt ggtgcagcac ttacaactaa tgtgtacagt gagctaatag cagatacaat
    20641 ccatataaat aaagatttat ttcaatttat actaaataat aaagggaaag aaagactgat
    20701 tttaataaca gattctatag aagctggtgg tcttgaagat ggcaattatt ctcttggagg
    20761 tcagaaagtc atagttaagg gtaatgaagc tagacttgaa aatggagcat tagctggaag
    20821 tgtgttgtct ttaaataaaa tggtatttaa cttcttagat aatacaaacc ttaaagtgaa
    20881 tgaagcaatt aatttagctt ctttaaatcc agcaacatct ttgggaataa atgacaaaaa
    20941 aggaagctta gaaataggta aggatgcaga tatagctgta tttgatgaga atttagattg
    21001 taaaatgaca ctttgcttgg gggacgtagt atataaaaat atatagtata caaaacaaac
    21061 tttaaagaca gtaaaaacaa tataaaaaat aataaattaa acttacatta gttaaagtag
    21121 tagttaaaat ttaggaggaa taagatgaga gtattagtgt gtaaagatta tgatggaatg
    21181 agtaaaaaag ccgctgaaat gatagcagct caaatagttt taaaaccaaa ttcaatactg
    21241 ggactagcta caggaagtac accagtaggt atgtatagag atttagtaaa aaaatacaat
    21301 gataatatag tagatttttc agatgtgatg agctttaatt tagatgaata ttataagtta
    21361 ccaatatcta atgaccaaag ctatgattat tttatgaaag agaatctatt taatcatgta
    21421 aacataaagc tagaaaatac tcatctacca aatggaatgg ctgatgatat tgaaaaagag
    21481 tgtctgaact atgaagcttc tatagatgca gctggtggta tagatgtaca agtacttgga
    21541 ataggtcgta atgctcatat aggttttaat gaacctgata ctaaatttgc aaaaagaact
    21601 catgtagttg aacttacaga gtctacaata gaagctaatg caagattctt taaatcaaga
    21661 gaagatgttc ctaaaaaagc tgtaagtatg ggaataggtt caatattgaa gtctaagaaa
    21721 atattgcttt tagcttcagg agaagaaaaa gctgatgcag tatataatac tgtttacgga
    21781 gatataactc cagaagttcc tggttctata cttcaacttc ataaagacac tatagttata
    21841 gtagatgaag cagcagcaag taaactgaat ccaaaagatt ataaattagt ataagaatag
    21901 aatgtagttt aagtgaaaaa tagctatcat tgaataatca aatttattta atgatagcta
    21961 tttttattta aattttttac ttctttttat ttaaattagt tattattgtt taaattactt
    22021 gcttattact ttttacgaaa actcgttatc aagaagtatc cgaataagat gttaaaaatt
    22081 attatgttta gtgggattct atcaagcata ataaaattac ctataattgg gatattacca
    22141 attggaaaca taaagaagaa tacaggcatc agtgatagta aaaaagatgg aaaacaaaga
    22201 agaagtaatc ttggaatatc aatataccaa ctaccatcct ttttgtattc tctaatcaat
    22261 aattcagttc ctagtaacaa accaatacca ccagaggaaa ttaaattaat aaaaatgtat
    22321 cttttaaagt cttgcatata accagtgtga aattgagtat agaaatcata atttaattta
    22381 acggctaaaa aatatataag caatagaatg attaaaaata aaagatatct aagagctttt
    22441 ttcattttaa attctccctt cagaaatact ttattcagtt ttattttgtt ggaatctgat
    22501 tttatcattt agtttaagaa atccataata ttagtgaaga atgaaataag tattatatat
    22561 gaataaatat ttttagaatt aaggtgaact gtagtgctta atataactat aatattaatt
    22621 gtttgaatat tcaataaaaa gtttaaaaaa tatcaatttt gatataaact gaataaatac
    22681 agttgaatat taaattatta ttttatcaaa aatatgcaaa gtactacacc ttcaaatatc
    22741 acctaaagta attaaaaggc aattaaagtg aagtagttca agtatttcta aaatgagttt
    22801 aataaattct ataataattt attttttgcc ttaaaattgc cttaaaatcc aaacaatttt
    22861 aaaactaatg tactataaaa agctggtata atttaaatat agtaaaaaat aagatttatc
    22921 ttatctattg ggatttaatt atttaatcaa tatatttata ccatttaatt taaataaaaa
    22981 gtctattaag gagtgagctt atgagtaagt taatttatat agcagatgat gaagataata
    23041 taagaaattt ggtaaagaca ttcttaaaaa atgaaggtca tgatgttatg gattttaaaa
    23101 cgggtgatga acttttagaa caatttaata taaaggagtg tgacttagta atactagata
    23161 taatgatgcc tggctcaagt ggttttgaag tatgtacaaa acttcgtgag aaaagtacag
    23221 tcccaataat catgcttact gcaagagata cagatataga ttatattaca gggataacct
    23281 taggtagtga tgattatttt acaaaaccat ttagcccaat gtctttggtt atgagagtaa
    23341 aatctatatt tagaaggata gagtttgaaa agaaacaaaa ttatgataaa tatagtaact
    23401 cgatagatat ggaattaaaa tttggtgatg taataataaa taaaaagaat aaaatcgtta
    23461 caagtaaaaa tgtaaatata gaccttacac caaatgaata taatctattg acttatttgt
    23521 ttgaaaatat agatagagca gtttccagag atgaattatt aaacaaaata tggggatacg
    23581 atatagaagt tgagacaagg gctgctgatg atacagtgaa gagattacgt aaaaaaattt
    23641 tagatacaaa tattttaata gaaactgtat gggggtttgg atttaggttg aaggagaaaa
    23701 gttaagatga ataatggaaa tgacaagaat agaattggaa agattaaatc caaatttaaa
    23761 ttaaagttct caaagaaaaa tataagcata aaaactagga ttttgttgag catactttgt
    23821 ttgataatta tagtatttat gataatatta gtatctttta atgtatttct tgatacatat
    23881 ataaaaacaa ctgcgaatga agaattgacg aagtctacag aaatagtaga acatatggat
    23941 agtaatttta gacctattaa gccaccacaa gatgatggaa agcttcctcc caaagtatta
    24001 tctaatttta tgagaaatgt acaagataaa gttaggatgg cagaaacaca atcagatgct
    24061 gatgctatgg tagttgattc taagtataac ctgatatttc caacaagaga ggatgatttc
    24121 ttaaaaaatg ttgatgagat ggagctgatt agggagtgta ttcaaaatga aaaattagat
    24181 ttaaattcag atgaaaatac acggatatct accagaaata aggattatta tatttcaact
    24241 gtaaaaatta ctagtatata tggtgaacaa gacaaatatc ttatactttt tatagacata
    24301 tcaaaaactc taaatctagc acaaaagata aatattgtat taatatctgt aatgtgtttt
    24361 gctggaatat tagcaatatt tacagctgtg attttatctg agaaaattgc taaaccgata
    24421 aaagagttgt gtgagtttgc aaaaaaaatg ggtcaaggag atttcaaaag aacctacttt
    24481 gacttttcag ataaagaatt agtagagctc tcaactgtta tgaataagag tgctgagtat
    24541 ctggataagt atgataatga acaaaaaata ttttttcaaa atgcatctca tgaattaagg
    24601 acaccactca tgtctattaa aggttatgca gaagctataa aatataatgt tatagatagt
    24661 aaacatgcaa gtgatataat tcttgaagaa agtgataggt taagtgatat ggttgaagat
    24721 ttattataca tttctaaaat agataatata actaaagatt ttgaacttgt agaatgtgat
    24781 ttaagagaag tattttcaaa ttgtggagct aggcaaaatg taagagctat aaataagggg
    24841 ataaaattta tttatgaatt tgatgaagaa atggttttat ttgaatgtga tgaaaaaaac
    24901 atttccaaag catttatgaa tcttatagaa aatgctttga gatacgctaa gagtgaaata
    24961 aaaatagtgt gtaagtataa tcaaaaaaat atagttgtga taatagaaga tgatggaatt
    25021 ggaatcaaga aagaagattt acctcatgtt tttgaaagat tctataaggg agtaggggga
    25081 aatcatggaa ttggattatc aatagttaaa tctattgtaa ataagcatgg tgggcgtata
    25141 tacgtagaaa atggcaaaaa aggagctaag tttactatat tatttaaatt gtaaaaaaat
    25201 tagagaaaat ataaagatgt ttgaagttgt tttttatata tatctgttgt atactgttga
    25261 aaaaagaaca atattaagct gacatatatt acaataattg acatttaaag taaatgctta
    25321 aatatagata cgaaaggaaa agtaaaatct gaagtgtatt taggtttaag taagcttctt
    25381 attttataaa aaatatgtat gaaagaacag ctgattttta atattacaaa tttagtaacg
    25441 gttgtatttg aagcttttgt catccatatg tttttatcag actttttagg tcagaaagaa
    25501 gggtatataa aagttgtaag atatgctaaa ctgggtttta taatatgttt aggattctgt
    25561 aatttaataa ctttaaaccc taaaatcaca atgcctttaa tttttatcct tattttttca
    25621 acatcatttt tatataaagg aaatttaaag acacgattgt ttactactgt tttattaagt
    25681 atattcttta tactgtcaga aattgtagtt acaagtattt ttgttttatt tgtaaaagaa
    25741 ggctttgaaa taatgcttga aaataatagt ataagagtat tggcgacaat tttatctaaa
    25801 attgtctttt tgttgacttg taaaattatt tgtctattta aaaaagatgt acatttagat
    25861 atgcccataa agtattggct ccctttattt ttaataccta tatttagttt atttctgtct
    25921 gtttctatct ttgatgtaag taaatttttt agtcttgaaa gtttaaaatt tctaagttta
    25981 atatctagtg ttggcatttt atata
//
LOCUS       DAMJWO010000063        25707 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.064, whole genome shotgun sequence.
ACCESSION   DAMJWO010000063 DAMJWO010000000
VERSION     DAMJWO010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25707
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.064"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(1..2493)
                     /locus_tag="PC366_002574"
     CDS             complement(1..2493)
                     /locus_tag="PC366_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2578075.1"
                     /translation="MNHNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPARTII
                     QNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLICGL
                     SSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIANIL
                     GSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGTLML
                     ICIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILSFEY
                     FLNPRILIVLILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGIAAPL
                     SGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCVSLIFMGLGMGFTMGT
                     PLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDLVGK
                     PSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKSLLN
                     KVQSADTTNITNITKEISTTMFDEKVPSIITKIQKNVQKGIDGTQSGINGIEDGENKL
                     NSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGVDKGIKGMEQGLEKQDEAIKELTT
                     AYNKIPTTEKTPTDNENNSNEQNQSNTSNSESDDTKNDSTENKNNNSSENKPNVNEQK
                     ESLNAQIQQLKKTRDDLNTKLQKNKTQKNELSKKLRSMESQKKELQSKLNNSINQKKD
                     MEKSLDTMQQQKKSLQAVLAKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTLQST
                     LNSGFKQMYITVFCVNLLAFIILLFYKENKTR"
     gene            complement(2507..3049)
                     /locus_tag="PC366_002575"
     CDS             complement(2507..3049)
                     /locus_tag="PC366_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2578076.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSNISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLNIIFTEIRNFINKVHNIQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            3292..4806
                     /gene="glpK"
                     /locus_tag="PC366_002576"
     CDS             3292..4806
                     /gene="glpK"
                     /locus_tag="PC366_002576"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDF2578077.1"
                     /translation="MEKKYVMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDEDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASVQWLRDELKIIESAKDSEMYAN
                     RVEDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVDIDRPKIVETTALGAAYLAGLS
                     VGFYIGRNEITSKWSVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            complement(4920..5549)
                     /locus_tag="PC366_002577"
     CDS             complement(4920..5549)
                     /locus_tag="PC366_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2578078.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRAVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAQTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            6138..6929
                     /locus_tag="PC366_002578"
     CDS             6138..6929
                     /locus_tag="PC366_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HDF2578079.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRSVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELEGIEVCPLENIEVCSSENIV"
     gene            6958..8178
                     /locus_tag="PC366_002579"
     CDS             6958..8178
                     /locus_tag="PC366_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HDF2578080.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVDTMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            8198..8893
                     /gene="pxpB"
                     /locus_tag="PC366_002580"
     CDS             8198..8893
                     /gene="pxpB"
                     /locus_tag="PC366_002580"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HDF2578081.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLEIDFDSLIENLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            8923..9909
                     /locus_tag="PC366_002581"
     CDS             8923..9909
                     /locus_tag="PC366_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase"
                     /protein_id="HDF2578082.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGARAYVSIAGGIDVPLAMGSKSTYTRSKIGGFEGRALKKGDYINTFIQEKDF
                     TINKKLNSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLD
                     GESIKHLNGADIISDGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(10128..10694)
                     /locus_tag="PC366_002582"
     CDS             complement(10128..10694)
                     /locus_tag="PC366_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2578083.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDICMGEKVVRLNPGDSTFIKANVP
                     HKIINPSKDTIARGYGVISPPIWPIKSK"
     gene            11046..12113
                     /locus_tag="PC366_002583"
     CDS             11046..12113
                     /locus_tag="PC366_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide epimerase"
                     /protein_id="HDF2578084.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESVILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIREAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEESKDISGGF
                     VMDGDIMNLVNKPGLGIEVNL"
     gene            12132..13292
                     /locus_tag="PC366_002584"
     CDS             12132..13292
                     /locus_tag="PC366_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HDF2578085.1"
                     /translation="MNTLFSNPGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPVSMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEETELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVSTILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            13305..15401
                     /locus_tag="PC366_002585"
     CDS             13305..15401
                     /locus_tag="PC366_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HDF2578086.1"
                     /translation="MIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKIESLKPISKEE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWEKTHKNEEIYSIRFGGNYMI
                     DMKDGIKLSTDVYLPDFVDSTKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWEPMIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPVEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPVEYYSVGFNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDNDLEEKYDSYIYNPKDPSVQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDAFSEEF
                     TVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNSFYKSEFMEE
                     GEIYKFTIITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTKEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(15560..15904)
                     /locus_tag="PC366_002586"
     CDS             complement(15560..15904)
                     /locus_tag="PC366_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDF2578087.1"
                     /translation="MEIKRYEGTGRMSRAVVHNNTVYLCGQTHAEGGVIEQTTEVLAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
     gene            16196..17086
                     /locus_tag="PC366_002587"
     CDS             16196..17086
                     /locus_tag="PC366_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDF2578088.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEVIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            17304..18590
                     /locus_tag="PC366_002588"
     CDS             17304..18590
                     /locus_tag="PC366_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDF2578089.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDICEIVAVAEPKKGRRE
                     LFTQKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKKFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF"
     gene            complement(18679..19122)
                     /locus_tag="PC366_002589"
     CDS             complement(18679..19122)
                     /locus_tag="PC366_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HDF2578090.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFGITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDRDKKKP"
     gene            complement(19146..19940)
                     /locus_tag="PC366_002590"
     CDS             complement(19146..19940)
                     /locus_tag="PC366_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HDF2578091.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKKIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            complement(20506..20982)
                     /locus_tag="PC366_002591"
     CDS             complement(20506..20982)
                     /locus_tag="PC366_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HDF2578092.1"
                     /translation="MKEILINPIGKICIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDNPELRSILETPKPYKSGPNVIGIFATRSPIRPNPIALTAVQIINIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSVDRVENPSVPKWCSHWPKSVEKSGEFNWEDEIEF"
     gene            complement(21083..22252)
                     /locus_tag="PC366_002592"
     CDS             complement(21083..22252)
                     /locus_tag="PC366_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2578093.1"
                     /translation="MLNIRTLCHEINDWIINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKNYLNVNVKFFFQPAEETIGGAQLMIEDGCLENPNVKYI
                     FGLHVNPNINKNLIELKYNTLNASTDTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIEGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIRE
                     ICDFTCKTFGGSISVEIEEGYPALINSNHLVDYVKQNAVELFGEENIILKDSPTLGAE
                     DFSYFLRHCEGAFYHLGCANREKNITSPLHTSTFDIDEDCLITGVMLHVKNVLSF"
     gene            22415..23278
                     /locus_tag="PC366_002593"
     CDS             22415..23278
                     /locus_tag="PC366_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HDF2578094.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYL
                     AGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVGKWDKFTYKSLVNALEFKDDLYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEENDLMELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            23349..23942
                     /locus_tag="PC366_002594"
     CDS             23349..23942
                     /locus_tag="PC366_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HDF2578095.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(24193..24828)
                     /locus_tag="PC366_002595"
     CDS             complement(24193..24828)
                     /locus_tag="PC366_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDF2578096.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAR
                     QGALYSPRVESLIKPIEMFTKKISNKLNRVIAFTDSHTPKSIELLSYPVHCLENDVES
                     ELVDELKSIENLQILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNIHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(24908..25639)
                     /locus_tag="PC366_002596"
     CDS             complement(24908..25639)
                     /locus_tag="PC366_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDF2578097.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLYMDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQNNKECKIPTLEEVLILISPTD
                     LILNIELKTDKINYPNIEKDVLELILKYNMKNRVLISSFNSNSLKNFHKLDPSVKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEDDILHCL
                     KLNVDGIFTNYPDIASNLLHSKQYS"
BASE COUNT         9549 a         3110 c         4196 g         8852 t
ORIGIN      
        1 ttatctagtt ttattttctt tatagaacaa taatattata aatgctagta gatttacaca
       61 gaatactgtt atatacatct gtttgaatcc tgagtttaga gtagattgta gtgtattttc
      121 tatttttgtt ctattatttt ctatggaatt tatataatcc aattttgatt tatcaaaagc
      181 ctttggtatt tcagttttta cctcttgtgt ctttgctaaa actgcttgga gtgatttttt
      241 ttgctgttgc attgtatcaa ggcttttttc catgtctttc ttttggttta tagaattatt
      301 taacttgctt tgtagctctt tcttttgaga ttccattgat cttagttttt tacttaattc
      361 gttcttttga gttttatttt tttgtaactt tgtatttaag tcatctcttg tcttttttag
      421 ttgctgtatt tgagcattta aactttcttt ttgttcattt acatttggtt tattctcgct
      481 ggaattgtta ttcttatttt ctgtagaatc attcttagtg tcgtctgatt cagaattact
      541 ggtattactc tggttttgtt catttgagtt attttcgtta tcagtaggag tcttttctgt
      601 agtaggtatt ttattataag cagttgtaag ttccttgatg gcctcatctt gtttttcaag
      661 accttgttcc atacctttta tacctttgtc aacaccagca ataccttttt ttacaccatc
      721 tattccttga ttaataccag ctctagcttt taccatattg tcaataccag tttgaactcc
      781 tttaatacca ctatttagtt tattttcacc atcttcaata ccgtttattc cactttgtgt
      841 tccatctatt cctttttgta catttttctg tattttagta attatagatg gaactttttc
      901 atcaaacatt gttgttgata tttcttttgt tatattggta atgttggttg tatctgctga
      961 ctgaacttta ttaagtaagg attttggaag tttgccacct gtcatgtcca tatttatatt
     1021 tgaagtatca ttcatatttg ggatagagac attttttaaa ttttttgcca tttcagggtc
     1081 tgattttaag tcatctatca tgttttcaag ttcttcaagt tgaactattt taggagttga
     1141 gggctttcca actaagtcca taatattatc ttgcacagat aatcctgcat gtgctataaa
     1201 tccaatcatt atagctggag aaattgaagt accaattgag cgtatcaagg ataatgttgc
     1261 aagtgctgaa ttagattctt ctaatcttgt atttgataac atcatatagt ttagaggagt
     1321 tcccatagta aagcccattc ctaatcccat aaatattaaa cttacacata cactaaatac
     1381 agtattggtt tttagagcaa ttaaaactag gtaaagagag cctatcatag atacagaaaa
     1441 tcctagtaat agtattttct ttgccccaaa cttgtcaata agtcttccgc ttaaaggagc
     1501 agcaatacct gcaaataatc ccaatatagc tacaaaatat ccaccagaac cagcatttat
     1561 ctttaatgca ttttcagcat actgtggaac gaataccata cccatcattc caataccaac
     1621 aattaaagat aaaataagta ctatcaatat tctcggattt aaaaaatatt caaagcttaa
     1681 aatagggtct ttagctctat tttcaataaa tatgaaaata ggtataagta caataaatgt
     1741 caataagtat ggataaactg atatatcttg tatagaattt ttaaaattaa aaaagtctat
     1801 attcataaga ccatataata gtgatacgat tatacatatc aacatcaatg taccaagctt
     1861 atctattttt tctttagatt cagacttatt gtttttaata cagaaaactc caccaataag
     1921 tatgattaaa caaattggaa ggtttacaaa aaatagccac ttccaatttt gagttccaaa
     1981 gatacttaga attgtgctac caatgcttga acctaaaata ttggcaatac catatgttgc
     2041 cccaactaaa cctaaagcca tgcctctttt attttctggg aaggtagttc caaattctgc
     2101 tgtagcaatt ggcatgattc caccaccacc aattgcttga ataacacgac caattaataa
     2161 aatatagaaa ttggaaaata gtgatgataa tccacatatt aatgaaccac taccaaatag
     2221 aaatatacta actagataca catattttct tcctatttta tctgctaatt ttccagagat
     2281 aggaattaca gaagcgtatg ttaatgtgta tatggtaatc atccaaattc ccgttttttc
     2341 atttactcca aggctatttt gtataatcgt tcttgctggt gatactattc cagtatcaat
     2401 agctcccata aatataccta atagataaag tgtaagtact aaaaatattt ttggattact
     2461 gtccttgttc ttaatactag tattatgatt caaggtaaac accaccttaa tgtattaatt
     2521 tttcaatata gggttttaaa tcttcaaatt ctatatgaag atatgttgaa tatgaaaaaa
     2581 acatttttat tatgatattg catactaatt tgtcattatt aaaaaaactt tctttttcta
     2641 aagcttcata tactttattt gaaagctgtt catgaaagtc gtctttgtgt tttttcattt
     2701 caaaaaatct ctctgtttca aaagtgttta aaaagtcatt gtattggata ttatgaactt
     2761 tgtttataaa atttcttatt tcagtaaaaa taatgtttag tttttttatg taatcttcag
     2821 tgtttttatt ggagtattca attcgcctta tcaataaatc ccattcagat tttgtgatat
     2881 attctattat ttcttgtttt gaattaaagt aattatatac tgtacctgca cttataccac
     2941 acctttgagc tattttcctt atgctaatat tcgagtaatc ttcttctaaa atcatatccc
     3001 gagatacttt taatatatct tcttttacat tttctaaaat ctttggcata ttaccacctc
     3061 ttttattaaa attattatga acactgttta ttatactcct ttaaaattta ttaatcaata
     3121 tgtaagctat aatgtataat attattatat agatatgata gaaaataagt gtctttttat
     3181 aaatatctat tatattaaat ttgtacttaa gtatgattat ttattgaaat atgtgatatt
     3241 aaatttttct ttttaataaa ttaaatatta tatgataagg agaatatggt gatggaaaag
     3301 aagtatgtaa tggcattaga ccaaggaaca accagttcaa gagctatact atttaataaa
     3361 aaaggcgaaa tagtgaaaat tgcacaaaaa gagttcaatc aaatttatcc aaaagctgga
     3421 tgggtagagc atgaccctat ggaaatatgg gggtcacaaa gtggtgtaat gagagaagtt
     3481 atagaaacag caggtataag accagaagaa attgcttcaa tagggataac taatcaaaga
     3541 gagactacgg ttgtttggag taggtatact ggtaaaccta tttataacgc aatagtatgg
     3601 cagtgtagga gaacatcaga aatatgtgat gaacttaaaa ataaaggatt ggaagaatca
     3661 ataaaagaaa aaacaggtct tttaatagat gcatactttt cagcaacaaa agtaaaatgg
     3721 atattagata atgtagaagg agctagggaa aaagcagaac aaggagagtt attatttgga
     3781 actatagata catggttaat atggaattta actcgtggga aagtacatgt aacagattac
     3841 tcaaatgcat ctagaacaat gatgtacaat ataaatgatt tagaatggga tgaggatata
     3901 ttacgagaat tggacatacc aataagcatg ttgccattag taaaaccttc tagctatgtt
     3961 tatggtcata cagatgagcg catgttatca ggagctaaaa tacctattgc aggatgtgct
     4021 ggagaccaac aagcagcatt atttggtcaa aattgtgttg aagaaggtac tgcaaaaaat
     4081 acttatggaa cgggttgttt cttacttatg aatacaggca gtaacatagt taaatctaag
     4141 catgggttac ttacaacaat tgcttgggga gttgatggaa aagtaacata tgcattagaa
     4201 ggaagtatat ttattggagg agcatctgtt caatggctta gagatgaatt aaagataatt
     4261 gaatctgcaa aagatagtga aatgtatgca aatagggtag aggatactaa tggtgtatat
     4321 gtagtgccag catttacagg tcttggagct ccatattggg atatgtatgc taggggttca
     4381 attttaggac ttacaagagg agcaaaaaaa gaacatatag taagagccac attggaatca
     4441 attgcttatc agacaaagga tgttttagaa gcaatgcaaa acgattcaaa attaaaacta
     4501 aaatcattaa aagttgatgg tggagcaagt aataataatt ttttaatgca atttcaatca
     4561 gatatattaa atgtagatat agatagaccc aaaatagtag aaactacagc tttaggagct
     4621 gcttatttag cagggttgtc tgttggattc tatattggaa gaaatgaaat tacttcaaag
     4681 tggtcagtag aaaaagagtt taatccaaat atgagtgaag agaagagatg taaattatat
     4741 aaaggatgga aaaaagctgt atcgagagct ttaagctggg aaaaagaaga tgaattggat
     4801 atttaaaaat taatcaaagt taaatttatt tgaatttaaa aagagcttta tgtaaaatat
     4861 gaagctcttt ttttgttgtt aattttgcat ttttatataa tcatactaaa ttatataatt
     4921 tatttttcgt tttcatataa aaacattggt atagaattgt aaatgtgttg gtcaccaact
     4981 actaagagaa tgtctccttc taaaaattca atatatggtc caggagatat tataagttct
     5041 tcacctcttt taattgcaac tattgtagca cctgtatttt gccaaaattt agtttgtgca
     5101 gctgtttgac caatatattt gcaattagaa tttatggtga actgaacggg cactaaagga
     5161 ttgattattt caagtctgtt ggaatagtct aaaattttat ttatagtatc taatatttca
     5221 ttttctaaat tagatttagt atctattaaa ttataaagtg ttgatttata tgatgatata
     5281 tttgtaatat ctctatattt ttttataaaa gaagaagctt tgtctggaga tagtacaata
     5341 acacctttac cctttatgct tttaacaacg ccaatgtcct ctaaaatttt gacagctctt
     5401 cttatcgttt ctggagatac attgtattta ccagccaaaa cagagcgtcc aaatagtact
     5461 gaatcctctt gtatttcacc cgtgtatatt ttatttgcaa tatccaacgc tattttttgg
     5521 tatattggca tcgtatagtt tttatccatt gtttttcccc caatacaaaa tttatgttaa
     5581 aaaaatatat aatcttaaca atactattgt ataatttata ggtttatatg tctacaatat
     5641 gtacaaatat tgtgcatgtt ttaaaataat attttaacat gcatttagta tacatgattt
     5701 tattatactt aaaactatat aaagaattaa ttataaaaat ataaagatat tttacttaca
     5761 aagaatgata attatataga tgaaagaaac aaataaatga agaaaaatga ttctgtcttg
     5821 catataaagt gattaaaaat gaaaaatact ttaaaaatga aggttaaggc ccttatttta
     5881 agtgaaaata attaattatt aactaaaaaa tggtaaaaag attttttgaa aaagaaatac
     5941 aaatgaatgt tcaattaaaa taattgcaaa aatattcctt aaatggtaaa attatattaa
     6001 ttaaatgcaa tagaatagtt gcaaaaataa aattgaatac aagtgataaa atatttcatg
     6061 caatatataa aataaacaaa atttaaaaat taaaactact tattctatca aaatgttagc
     6121 aaggaggggg tcataaattg tataaagtag atttaaatag tgatttagga gaaagttttg
     6181 gaacgtataa gattggttta gatgaagaag ttttaaaata tatttcatca gctaatatag
     6241 cttgtgggtt tcatgcaggt gaccctagtc atatggaaaa aacagtacag ctagctaaaa
     6301 aaaatggagt gaaaataggc gcacatccag gtttcctaga tttaatagga tttggaagac
     6361 gtgagatgaa aataacaaag caggaagcta aagattatac aaaatatcaa ttgggtgctt
     6421 taatggcatt tgcaagttca aatggatgta atatacaaca tgtaaaacca catggagcat
     6481 tatacaatat ggcagctaaa gataaagagt tagctatggg gatttgtgaa gctatatatg
     6541 aagtcgataa agatattata ctgttggggc tatataatag tgaaatgata aattctgcta
     6601 aagaaattgg acttaggttt gcaaatgaag tatttgcaga tagagcttat gataataatg
     6661 gttttttggt tccaagaagt gtagaaggag cagttataca tgatacaaaa catgcaatag
     6721 atagggttgt taggatggta aaagaaggaa ctgtagaaac tttaacaggt gaagttatac
     6781 atatcaaagc agattctata tgtgtacatg gggacaatcc aaaagcaata gagtttgtca
     6841 aagaaataag aaagcgtttt gaattagaag gtatagaagt ttgtccatta gaaaacatag
     6901 aagtttgttc gtcagagaac atagtataag actgataaca tgagggggag ataaaatatg
     6961 agtacaaaaa atattacaga taaaactaaa aataaaaaag atgtcggagc acttataggg
     7021 gctgcattta taatggcaac atcagcaatt ggaccagggt ttttaactca gactgcacaa
     7081 tttacccaag attttggacc aaatttttca tttgtaattt taattacaac aatccttttt
     7141 ataggggctc aagtaaatgt atggagagta attggtgtat caggacttag aggtcaggat
     7201 atagcaaata aaataatacc gggattaggt tatttagtag cttttttagt agctcttgga
     7261 ggattagctt ttaatatagg aaatgttggt ggagctgcac ttggtatgaa tgtaatgttt
     7321 aatatgaata tgacattagg aactgtatta agtggattaa tagctatatt tgtatttatg
     7381 tcaaaaaatt caaattctct agtcgataag ataactaaat ttttagcatt aggaatgata
     7441 attatagttg gatatgtagc aatatcaaat catcctcctg ttggagaggc agtatcaaga
     7501 atggtaaaac cagaaaatcc aaaaggattg atattcccaa taataactct acttggagga
     7561 agtgttggag gttatataac ttttgctgga ggacatagat taatagacgg tggaataaca
     7621 ggagaagaaa atataaaaga aataactaaa tcttctcttt tgggtatatt agttgacaca
     7681 atgatgagag ttcttttatt tttagcaata ctggcagtgg tttcaaaagg tcttcaactt
     7741 gacccagaaa atccagctgc ttcagctttt aaatttagtg caggagcaat aggatataaa
     7801 ttctttggac ttgtattatg gtctgctgca attacatcag ttataggagc tgcttataca
     7861 tcagtttctt tcttaaagac actaaatcct tttatagata aatatgaaaa atattttata
     7921 atagcattta tagcaatatc aacacttata atggcattta taggaaaacc agctacttta
     7981 ttaattttag caggagcttt aaatggattg atacttccaa tcacattagg aattatgctt
     8041 atagcatcta aaagaaaaga tattgttgga gattacaagc atcctacatg gcttttaata
     8101 tttggattaa tagtagtttt aatatctgca tatacaggaa taacttctct tagcagccta
     8161 ggtgctttat ttgcttaatt tagaagaggt gacatttatg gaaactagat acttgatatc
     8221 aggggataag gcagtggttg ctgaatttgg aaatgagata tcagaagata taaacaaaaa
     8281 agtaatttca tttatgagag caatagaaat atcgaatctt aaaggtattg taacagaaat
     8341 ggtaccaaca tataggtcac ttatgataag ttataatcca ttagaaatag attttgatag
     8401 tttgattgag aatttaaaaa aaatagaaga taatttggaa agtatagtat taccaaaacc
     8461 taaaatacat gagattccag tatgttatga tgaggttttt ggtatagata ttaaaaacgt
     8521 tgcaagctac aataatctca ctgtagatga agttataaaa atacacacaa gcagagagta
     8581 cttgatatat atgctagggt ttactcctgg atttccatat ctaggtggta tggatgaaag
     8641 aatagctaca cctagattag aagtgccaag gactaaaatt tatggtggga gtgttggaat
     8701 agcaggttcc cagactggtg tatatcctat tgatagtcct ggtggatggc aaataattgg
     8761 taggacacct ttaaaattat atgatgaaaa tagagaagaa cagattttgc ttagagctgg
     8821 agactttata aaatttgttc caataacatt agatgaattt atagaaatcg aaaaaaataa
     8881 cttaagtatt taaatatcgt tatagtacag ggagtggtat atatgggatt caaagttgaa
     8941 ttaggaggtt tccaaacatt aatacaagac agaggtagag ttggctatgg tcaatatggt
     9001 gtatctggat gtggagcaat ggatgagtat gcacatagag taggaaatat attagtagga
     9061 aattctgaag atgaggcttc tttagaagtt ttaatgttag gtcctacaat tacctttgat
     9121 gaatatacgc aaatagcagt aactggggga gatttagggg ctaaaataaa tggaaaagaa
     9181 attcaaaact ggaggtcata tcaaataaat ccaggtgatg tattatcatt tagaggtgtg
     9241 aaatcaggtg ctagagccta tgtgtcaata gctggtggaa tagatgttcc acttgcaatg
     9301 ggaagtaagt caacttatac aagatctaaa attggcggat ttgaaggtag agcacttaaa
     9361 aaaggagatt atataaatac ttttattcag gaaaaagatt ttacaataaa taaaaaatta
     9421 aattcaaaat atattccaac ttatagttca gaaatcgtac taagaattgt aaaaggtcct
     9481 caatttgatg ctttttctaa cggtgaagta gagaaatttt tatcaaataa atacaaagtt
     9541 acgaatgaaa tagatagaat gggttgtaga ctagatggag agagtataaa gcaccttaat
     9601 ggagcagata ttatatctga tggtatttct tatggagcta tacaagtacc tggtcatgga
     9661 aaaccgatta taatgttatc agatagacag actagtggtg gctatactaa gatagggaac
     9721 gttataagtg tagatttgta taagttagca caagcaaagc caaatgatgt agtaaaattt
     9781 gaacttgtag atatatatga agcacataga ctattgagag agcaagaaga taagattcaa
     9841 gatatctaca agagtatgaa aaatataaga gttgtaaagg caaaagtatt aaatgatata
     9901 gcagtttaat ttaattttaa caaatacaat ttttattata atttataata taacttacaa
     9961 atagctattt actatttacc ataattaaga tggtttagat tagtcaaata gctatttttt
    10021 tagtttgagt aaatatttta aatttaaata aatacttcaa ttttaaaata aaagcaatat
    10081 ttaaatttat tatattatct acaaaaagta ggtgtgttat gttgagttta tttagatttt
    10141 attggccaaa ttggaggtga tataactcca tatccacgag ctattgtatc tttacttgga
    10201 ttgatgattt tatgtggtac attagctttt ataaatgttg agtcacctgg atttaatcta
    10261 actacctttt cacccataca aatatcaacc acaccactcg ttaccaccat aatttcttct
    10321 gatgcatgat agatataatc tttagcatcc tcactttctg gtttaagttc aaactctaca
    10381 aataaaattg aaggtgtaaa ttcagttgta ggcattggag atactatctc gtaaaacatt
    10441 tcactctttg gaaatttcat cataactcta tcttcttttc taattactaa atcatcagta
    10501 ttattgtcat ccataaacat atataaagga gtgtctaaaa cttcagcgat ttttctcaat
    10561 gaagacaagg atggttcaat agcatctctt tctatttgag agatataact tatagataaa
    10621 tctgtcaatt tggaaacatc acttaatgtt tttttcttgc tttttcttat atttctcatc
    10681 ttttcaccta gcataagaac ctccaaataa taaaattaat ataaaatatt cgcttaaaac
    10741 aaagtaatta tagcacaaca tagaagtagt ggcaataaga atacatagta gattttgaca
    10801 attaaaattt aattaaatcc aaataaaagt ctatgaaaat gaattattgt taaattaata
    10861 taaagaaaat aataataaaa aaatttaata gaagagtatt aattgaatta agattatcac
    10921 attatatttt ggaaaagagt aaattttcag taaattatct tgacatatat attgaagtaa
    10981 taatataatt taaagtataa aattttaaaa attgaattat aacttcaaaa aataaggagg
    11041 gtaatatgaa gataacagat atcaaatttg aaaagcttag aattaaatta aaaaaacctg
    11101 tagtagtttc atttggagta attgaatatg gagaaagtgt aattttaaaa attgaaactg
    11161 atgaagggta ttgtggattt ggcgaagcag cacctcttgc agcagttaca ggtgaagttt
    11221 tggataatgt tctttcagta ttgcttatgt ttaaaaaaga gttaataggc aaagacccac
    11281 tagatattga aaccatacat acaatcatgg atggaattat tataggtaat acttctgcaa
    11341 aagcagctat tgacatagct ttatatgata ttaaaggaaa aattatgaat gcacctcttt
    11401 ataaagttct tggaggattt gatagtaaag tccaaacgga tattactata agtatagata
    11461 agccagaaaa aatggcagta gaagctttag aaagagtaaa agaaggtttt aggatattga
    11521 agcttaaagc aggtataaat cctgaagacg atattgaagc tgtaaaatta attagagaag
    11581 ccgttggaga gagtataaga attagaattg atgcaaatca aggatggaac gtaaatagca
    11641 gtataaatac tatcaaaaaa ttagaagaat ttaatgttga tgcaattgaa caagcacttc
    11701 cacattggga tttagatggt actgcttaca taagaaataa aagtaataca aaaattatga
    11761 tagatgaatc gttacattca ccaatagatg caattaaggc tataaaaaag aatgcagttg
    11821 atacatttaa tattaagctg atgaaatcaa gtggaatata tcctgctata aaaatcaaca
    11881 acatagctga ggcaagtgga gtaaattgta tgttaggatg tatgctggaa acgagaattg
    11941 gtataacagc agcagcaaat ttaatagcat ctaaaaagaa cataacagaa gctgaccttg
    12001 atagttttat gttttgtgaa gaatcaaaag atatatctgg aggatttgta atggatggag
    12061 atattatgaa tcttgtcaat aaaccaggtt taggaataga agtaaactta tgataaattt
    12121 ggaggttaaa tatgaataca cttttttcaa atccaggtag tatacttgct gtaatgacat
    12181 caatgattgc attgggtttt tacttacaaa gatacaaagc cattaaaagc ttaggaccag
    12241 cacttacaat aatcataatg ggaataatac tttcaaactt aaaagtagtt ccagtaagta
    12301 ctgagttata tggaactatt tcaacatatg ctatcccagt ttctatgact ataatgttga
    12361 tgagtgttga cttaaaagaa atgacaaaat tatcaagaga acctttaatt gcaatttttg
    12421 tagctgtatt aactgtaagt atcatggcat ttttatttgg attagtattt gcagaaaaaa
    12481 tatcagaagg ttggaaggtt gctggaatgt ttgtaggtac atacactggt ggaagtgcta
    12541 atcttacagc tattggaaca ggccttaatg taagtagaca aactcttgct gcagcaaatg
    12601 cagcagacta tgtaattgga gtaccaacat tgatatttat gtttgctcta ccagcaatat
    12661 taaaaaattc aaagaagttt aaaaaacttt ggccatatca tgtagaagaa acagaattag
    12721 aagattgtca aaatgaagaa tttatggagt caaaagaatg gagtattaaa gatatagctt
    12781 ggatgttggc tataggtttt gttgttacag aagtttcaac aatacttgct ggatatttca
    12841 attcaagttt tagtagtgca gcaagaatac ttttagttac aacaatttca attataattg
    12901 ctcaattaaa gccagtaaag aaactaaagg gaaatttaga tttaggatta tttgttgcat
    12961 tattcttttt atgtacaata ggtttttcag tagatataaa agagttttta ggttcaactt
    13021 ttactataac actttactgt tttagcataa tttttgcttc atttgttttt catttaggca
    13081 taactagact tttaaagata aagtatcaat atgtaatact ttctatagta ggagcaattg
    13141 ctgatggtcc tacttcagct ttagtagctg cttctgcaaa gtggaattcg cttgtaagtg
    13201 tagcagtcgt aatgggagta attggtggag tattaggaaa ttatgcaggt atatcagtgg
    13261 catatgcaat aaagatgtct ctaggattat aggggggagt ttaattgata aaatttaaat
    13321 tatacatatc tggactatac agtggaaatg taatctttga tggcgattta ttaattgaaa
    13381 agttgaatcc ttttacaaat aaaatagaaa gtttaaaacc aataagcaaa gaagaaaata
    13441 catactattt aaatcttaca aaaatagatt taaagtcttt atttaataac tttgatgtat
    13501 atactaaaag cttagtaaac acagataaag acacagttat aaataactta ggagaaacgc
    13561 attctaaact taatgaatat atatgggttc aaagaaacaa aaagttccca ctagatataa
    13621 ttattgtaga taataaaata gtaggtttta tctgtttatc cagagaaact tgtactatat
    13681 taattatgga tggatatgaa gagtatactg tattaaaaga atgggaaaaa acccataaaa
    13741 atgaagagat atattctata agatttggtg gaaattatat gattgatatg aaagatggta
    13801 taaaactttc tacagatgta tatctccctg attttgtaga ttctaccaaa aaagcaccaa
    13861 caattcttat gagaactcca tatggaaaag aaaatgataa agaaatatat tataaatatg
    13921 tacaaagagg atatgctgtt gtaatacaag atgttagggg aagaaatgaa tcagaaggta
    13981 agtgggaacc tatgattcat gagagggaag atggagatag taccataaat tggatagtat
    14041 cacaggaatg gtcaagtgga atagttggaa tgcttggagc atcatatctt ggttatgtcc
    14101 aatgggcagc tgcatcttca ggcaataagc atcttaaagc tttagttagt atagtaacat
    14161 caggaagccc ttttattgat ataccaagaa aaggaggagc ttttgtatct ggtatgcttg
    14221 catgggcatt tatggtatca agaaataaag ttgatagaag taaaatggta agagatgatt
    14281 gggatgatgt tttaaacata cgaccaatag aaaatatacc tgttgaagct cttggatata
    14341 gaattgaatt tctggaagaa tggttaaaga gagtagaaaa agatgagtat tgggatttga
    14401 tggattggca tttacaaaaa gataaaataa atgtacctgc attggttgta tctgggtggt
    14461 atgatgataa tagtatggga actacagagg ccttagatgt tataaaggac tatgaaaaag
    14521 gaaagagaaa ggctattcta ggtccatgga tgcataattc aaatacttta agagatataa
    14581 atggtatttc tttaggaaat agttcattaa gatatgattt ggattataat tatctattat
    14641 ggtttgataa atacttaaaa ggtatagaaa ataacataga tacgactgct ccagtagagt
    14701 attactctgt aggttttaat aagtggaaga cagaagaaaa ttggccaata ataaataaga
    14761 tagataaaag tatgtatcta ataagtgatg gaaatgctaa cacatcttta ggaaatggta
    14821 gattagtatt tgataatgat ttagaagaaa agtatgatag ttatatatat aatccaaaag
    14881 acccatcagt acaactaatt gatatgtcag agaatgaagt tggagttcca aataactaca
    14941 aagatttaga aaaaagaagt gatatgttgt gttatacatc agatgctttt agtgaagaat
    15001 ttactgtaac aggtgatata aagttagagt tttttgcatc aagttctgcc aaagatactg
    15061 actgggttat aaaaattatg gacgtggatt tagatggaaa ttcaattaaa ttagctgatg
    15121 gtatacttag tgctagattt agaaatagtt tttataagtc agagtttatg gaagaaggag
    15181 agatttataa gtttacgatt ataacttcaa aaatatcaaa cacgtttaaa gttggtcata
    15241 aaattagact agatataacg tctagtgcta aaaactttat tttccaaaat agcaacacga
    15301 aagagggata taatagtatt gaatatatag aagcaaagaa tacgatttac catggaggta
    15361 aatatccatc taaattgata ttgccaatag aaaataagta aatttatata gattaaatag
    15421 tgaggaggtg tctcaaaatg aattttttag ttcgtgagac actttctttt atacgaaatc
    15481 aaatatattt tcatcatttc aacaatgaaa aagaggctta tctctctgtt ttgagatagc
    15541 ctcctataag ctaaattgat tattttgtag ctgcaacaac gctcatttca actaacaaat
    15601 gctctctagc aagtctagct tcaacacaag ctctagcagg ttcaaatcct ttttcaaccc
    15661 aagcatccca aacagagttc atagcttcaa agtctttcat atctcttaaa taaatagtaa
    15721 cagatagcaa atgttgctta tctgaaccat atttgtttaa taaatcttct attttagcta
    15781 aaacttcagt tgtttgttca attactcctc cttcagcatg agtttgtcca cataaataaa
    15841 ctgtattgtt atgaactaca gctctactca ttcttccagt tccttcatat ctctttattt
    15901 ccatatttta aatacctcca tagttaagaa atctattaaa aatctaaata ataaattaaa
    15961 aaaagtctat actatataaa attatattat atattctgat aataatccat aaaaacatat
    16021 aactttttag ctataattat tattgttatt aattgaaaag acttattagt tacttgacat
    16081 agtttacact tttaattata gtataaattg gaatatttag ataattatta tttaatgtat
    16141 aagctaagtt tttaattaat atggctttat acatttatat agaaaagagg tacgtatgag
    16201 tagcacaatc aaatcaaatc gaataaaagg tataatgttt ataatagcat cagcgcttgg
    16261 ctttgcaatg atgtctgcat tcgtaaagct agctggagat ttaccaagtt ttcaaaaagt
    16321 gttctttaga aatctggtat cagctataat agctttttgg cttatcataa aacataaagg
    16381 aagtctaact ggtaaaaaag aaaatttaaa agtactttta tataggtcaa tatttggaac
    16441 tctaggagtt atatttaact actatgcaat tgacaagttg atgctttcag atgctaatat
    16501 gctaaataaa atgagtccct tccttgtagt aatattttgt gcaattgctc taaaagaaaa
    16561 aataaatgta aagcagatag gagctattat aattgcattt ataggagctt tattcataat
    16621 aaaaccaaca tttagtgtag aagtaattcc atatcttggg ggaattgcag gagctgtatt
    16681 tgcagcaatg gcatatactt gtttaagagt tcttggagat agagaagatt actatacaat
    16741 tgtatttttc ttttcagttt tttcattagt tactgtaggg ccaattgctt ttgcagtata
    16801 tgaaccaatg acccttatgc aacttatata tctattacta ggtggagtat ttgcaagtct
    16861 aggtcaattt ggaataactt tagcatataa atatgcacct gctaaggaaa tctctatatt
    16921 tgactatagt aatataatct tttcagcaat tttaagtata ttcttattca atgtctatcc
    16981 agatatgtta agtgttgttg gatatttaat agtattttcg gcagcatttt atatgttttt
    17041 atacaataag aagttagata aattagacaa agaaaagaag aagtaaacta gataaaagtg
    17101 tttttataat ttgtattgaa tatttaagtc tttgtattaa aattaaagaa aatttaatta
    17161 aaaatgtttg gtatattaac ttataacagc agttaaaatt gaaaaattat aactgctgtt
    17221 tcttttatta aaaatatcca aatgtctgta aaaatagact ataatagagt agtataaata
    17281 atataaaggg gataaattaa agtatggaaa aagtgaaagt tgctgtgatt ggagcaggta
    17341 atagaggaac gtatgcatat gctccatata tttatgaaaa ttctgatata tgtgaaatag
    17401 ttgctgtagc agaacctaaa aaaggaagac gagaactatt tacacaaaaa tataacctag
    17461 atagtaaaaa tgtatttgaa actttagaag acttttttaa acatgacaag atggcagatg
    17521 cagtaataat agctacaaat gatgatagac attatgatgt agcaaaacta gctcttgaaa
    17581 aaggttatca tgtactatta gaaaagccaa tgtctaatag tttagatggt ttggtacata
    17641 tagatgactt gtgtgataag tataaagata agatttttat gatttgccat gtactgagat
    17701 attctccatt ttataataaa ttaaaagaaa ttgtagaaag caaaaaatta ggagagctag
    17761 ttagtataca atataatgaa aatataggat attggcattt tgcacatagc tttactagag
    17821 ggaattggag aaatagcaat gaaaccagcc ctttaatttt agcaaagagt tgtcatgaca
    17881 tggatatttt gttatattta gtaggaagta gatgcaaaaa aatatctgca tttggaagct
    17941 taaagcatct taataaccaa aatgctagtg gagagatggc acaaaattgt cttcagtgtt
    18001 tagttgaaaa aaaatgtcca tattcagcaa agagaattta tttagaaaaa gatagaagta
    18061 taaatagagc tgttcacata aatccaactg aagagaatct attaaatata cttaagacaa
    18121 gtccatatgg aagatgtgtt tacagatgtg ataataatgt tgtagacaat atggtaaata
    18181 tattacagtt tgaaaatgga gtgacggcta cttttaattt atgtgcattt actaaagaaa
    18241 atggaagaac tataaagtta atgtttagtc atggtgaagt tggtggggat ttaaataaaa
    18301 atgagataag aattaaaaaa tttggaaaaa acgaagaaat agttatgaat ccatcaaatc
    18361 aacagaatat ggtagaggaa tatgatagaa atcttatagc tgaatttatt aaattagttt
    18421 caaataaaga actagaaaag ggtagagtag cagcaaaaga agctatacaa agtcatgtaa
    18481 tggcatttgc agcagaatat tctagggtca gtgatgaagt agtgtatata gaagaatttt
    18541 ttgatagtgc taagcaaatg actaaggaga tagaagaaac tatattttaa ttaataaaaa
    18601 tttattaaat aaaataaaga tagattaaat aatagaaata cgaaaatatg tgttctatta
    18661 aggaatctat cttttttatt aaggtttttt cttatcccta tcaaaaaaat ccatacattc
    18721 tgataaaaga taagaaagta aagcgaataa gatttctgta cttaaaggaa tcgttactga
    18781 atccataaag gtatcaatta tgttcatagc tagaaaagtt agtataaaat caattataaa
    18841 ttcgcaaagt ttatatattg agtatggtaa tttgtttaca tatctgaata tatctaaaat
    18901 agtagtgcat agaaaatcaa ttggagtggt tatacaaaaa tatattaaaa agaaaattaa
    18961 tacagctcca agagatttat attcaaatcc taagaatgat aagaagccaa ttcctataac
    19021 cgtgaaaata caaaaagtta taccaaaaaa aacagcaaaa aataaaaata cagaaataaa
    19081 ttcgcctaaa ggaatccttc ttttattact tatcttaatc aactccttaa tttatgatat
    19141 gaaatttata taaataataa cattcttaaa aattcataat agtcctctgt ttcaaatagt
    19201 actgtttgag aatctatttt tttcatattt ggataaaaag aggccttaaa agctttataa
    19261 tgttctctaa attttatttc tatcttaaat ttatctggca attttattaa gtgcctagat
    19321 aaatctccag ataaagcttt tttgacacct ttttcaattt tttttagtgc aaggtttgga
    19381 tggattgaaa ttgaaccatt tccaattcct tttgacacag gaacagtgac tatatttgga
    19441 tttagttttt ttgcactctc acaaagcatt tcatctccac ttaaaaatgc tacaggaaca
    19501 ttataatatg cagcaatata agcatttata gtaaattcag atgctatttc atcatttatt
    19561 ttaaaatagt cataatcaat atccatagta tgagaaagtg gattaccatt acaagtagct
    19621 ccagagtgat agccggtgaa tatacatgca tcaaagcttt catcaattcc agccatcata
    19681 actagtgggt ctttggtcca tcctctaagt attttgacgt tttcaggtaa aatatttgga
    19741 ttaatatttc taccactgtc atgtgcatct ttaacaagta tttcatgtac accagattga
    19801 gtagctccat cacatgctgc tgttatctct ttactcattt gtgttctata gtgttgtgaa
    19861 aattcacatt caagttttgt ttcatcccaa tttacaatac cacaagtacc ttctatatca
    19921 gcacttaaat acaatttcat aatatatacc cccttatgtt tattattgat gataataaca
    19981 gataacagaa aatacataat caataaaggg cataaaaata ttatgtctta ctattaatta
    20041 ttattaaatc tgtaactgaa aaataactaa attggtatta aaaaatataa cactatgtgt
    20101 catttattta tatagttttt tatatctgat gtttatataa aattgtaaca tataagtggt
    20161 tacatttact agtttaacat agttaaaata gttaggtatt atttttaagt taaattgatt
    20221 attataaaat cgtagaataa aagaaaaatt taatttatta aaatgcatga aatgtttttt
    20281 cctcaacata atgctaaatt aaactcaaaa agaaataata gaaaaatctt atgtagctta
    20341 gaaagaatgt gaatgattta agggaaaaat agaaatttat tatataatat taggctgtat
    20401 tatgtaatac agcctaatat tatatgtata tgtgacataa aatcttggta agtgtaaata
    20461 aaataaatgt ggaaaacaaa ttaatgaaat caagaaaaaa gtaatttaaa attcaatttc
    20521 atcttcccaa ttaaattctc ctgatttttc tacactctta ggccagtgac tacaccattt
    20581 aggaacggac ggattttcaa ccctatcaac gcttggagta tatggcttta agtctataac
    20641 aggactatta tcattagcat caatatatgg tatttttatt ataccatttt catggtcgat
    20701 attgataatt tgtacagcag tcaatgctat tggattgggt cttataggtg accttgttgc
    20761 aaatattcct ataacgtttg gtccactttt ataaggtttt ggggtttcta aaatacttct
    20821 tagttcagga ttatcaaacc catcagccca ccaaaataca tttaaatgac tgaaatcgtc
    20881 gagttcattt aatgcaggta catacttttt gtctaattta ataaagacct cttcgccttg
    20941 aatacatatt ttacctatag gatttattaa tatttctttc ataatattac ctccaactat
    21001 ttaatttatc atttgtaatt ttagggtata acatgacatc atgtgagggt caatataaaa
    21061 taataaataa aaatattaat agttagaatg ataatacatt ttttacatgg agcatgacac
    21121 cagtaataag gcaatcttcg tcaatatcaa aagtagaggt atgcaaaggg gaagtaatgt
    21181 ttttttcacg atttgcacaa ccaaggtggt aaaaagctcc ttcacagtgt cttagaaaat
    21241 acgaaaagtc ttcagcccca agagtgggcg agtctttaag gataatattt tcttctccaa
    21301 acaattctac agcattttgc ttgacgtaat ctactagatg gtttgaattg ataagagctg
    21361 gataaccttc ctcaatttca acagaaatac ttcctccaaa tgttttacaa gtaaaatcgc
    21421 aaatttctct aattcgtttt tttgaaaact ctctagtttc aggagtcaag gttctcaaag
    21481 taccccttat aaccactttg tcacaaacta tattttcctt gattccacct tcaatctttc
    21541 ctagagaaat aaccacagaa tcagttggat ttgtgtttcg actaacgatt gtctgtagag
    21601 ctgtaataat atgagcagat ataacaatag catcaatacc ttgatgtgga taagctccat
    21661 gacattttga accatgtaca gttaattgaa gtgtatcggt ggaagcattt agagtgttgt
    21721 attttaattc aattagattt ttgttgatat tgggatttac atggagtcca aatatatatt
    21781 ttacatttgg gttttcaaga catccatctt ctatcataag ttgagcccca ccaatagttt
    21841 cctcggcagg ttgaaaaaag aattttacat ttacatttaa gtaattcttt aatttaaata
    21901 gtatattaca agtacccagt aaaatagcag tgtgtgcatc atgaccacat gcatgcattt
    21961 taccaatatt aatagattta taagaataat taagttcttc tgttataggt aaggcatcta
    22021 tatcagctct tatagcaact gtttcaaagt ttggactcac gttaatgtat gcagttatcc
    22081 ctgtatgatt cttatattca atataattta tacctatttc atttaagtat ttaataattt
    22141 ttttcttagt ttgaaattct tctaatccaa gttctggagt cttatgtaaa tctcttctta
    22201 tatttataat ccaatcattt atctcatgac aaagagttct tatattaagc ataaaacaca
    22261 tcctaactat attaaaaatt tatttttctt cattaattat attattttat gtaaatcatt
    22321 attatgtatc aagtacaaat aaaatatctt ataattatat tagagatatt tagtatggag
    22381 aagaatatat cattttataa gaagaggtgt ttaaatgtta ggaataattg cgccatctgg
    22441 gccattaaga aatacaagtt tggaggaaat aaagtttaat ttagaaagtt atggttacga
    22501 agttaagttt tctgaaagtt gtagtttaaa ttataaaggt tatttagctg gtaatgatga
    22561 tattagagca agggatatag aagatatgtt tttagataaa gatgtagata taattatgtg
    22621 cttaagagga ggttatggaa caacaagaat attggataaa ataaattatg atataataaa
    22681 gcaaaatcca aaaccattta taggtttttc tgatataaca ggtttaaatt tagcttttta
    22741 taaaaattgt ggacttttac catatcatgg aataatggca gcaaatgtag gtaaatggga
    22801 taaatttacc tataaatcat tggtaaatgc tttagaattt aaagatgact tatatttaga
    22861 aaatccaaaa gaagaaaaga tttatactgt atgtgaaggt aaagcagagg gaataataat
    22921 gggaggaaat ttatccttaa taattgccac aatgggaaca aaatatgaaa tagatgcaaa
    22981 agataaaatt ttgtttattg aggaaattgg agaacctcaa tataaactgg atagaatgtt
    23041 aacacaacta tattcttcag gaaaacttga ggaatgtaat ggtataattt ttggagattt
    23101 taaggattgt attgaagaaa atgatttgat ggaattacta atagaatttg caaataaggt
    23161 caataaacct tctatatata atcttcagtc aggacattgt atcccaatga taactattcc
    23221 tttgggcaga atgtgcgaat tagatgctac agaaaaaatc gttaaattaa aaaaatagtg
    23281 tgtatataaa tataatagaa atatggtata atcttataca agtaaaaatt tagctaggag
    23341 gatgaaaaat gtctgatgat agaataatag actttaacga actaaagaac aaagttaaag
    23401 attctgatgt agataaattt gagcaataca tatataactt atatttttct gttatggatg
    23461 gaaagatgtc catggctgag ttttcaagaa aaatattcga ttatatgaga gataacaaca
    23521 tatctcaaga aaaatttatg aaaatacaaa agcaatttat ggagagatat ggtatggaca
    23581 ctgaagaagt agaaaaacaa cttagaaact ttggaatcga cccttctaca gcaggtttta
    23641 tgagtaataa tacttccagc aaagtatcta cagaagattt agagtcattt aagaagagtg
    23701 caggatttta tgagaaatat ggagaaaaaa tccaaccaaa gagttgtata acaacattta
    23761 taaaaaatga cttaaatgat attaatgtaa taatcgacca agaaaagata atgctttgta
    23821 gtgatagaaa aataaatctt atggattcag aactaaatga gtttttatta gaatataaga
    23881 atatgtttaa taaaaaaata aaggtagtaa tgtgcgaaac tacgaataag tatgattatt
    23941 aaaaaatgaa tttaaatact gaagtagtat caattaattg tactacttaa aaataaaaat
    24001 cgcaatttat tattccttat aaatttgtat aaggaatatc taaactgcga ttttttatat
    24061 tgtgaagatt agtcataata gatagtgttt taaattgtaa tcttctcact aaaactgtgt
    24121 ttttctatta gaaattttat taaaaataaa tatctgataa ttgtattata tgggatgtaa
    24181 agtattagag gcttaacgaa tctcttttaa tacattaact ccattttgaa tcatactgtt
    24241 gaaaaatact aagtttaaaa tctcagcagg gtgaatgtta ggaatatcat aagtatctac
    24301 taaattcata ggtacaacta tatttttttc aatattatgt tgattaaaat atgattttag
    24361 agttattgca aattgatata tgcatatatc tgtgcaatcg ccaactataa ttatattatc
    24421 tatattatca aaatccaaat tttctaatgc aaaaaatcca ttagtagaat ttttaggaag
    24481 aatttgtagg ttttctatcg acttaagttc atcaaccaat tcactttcta catcattttc
    24541 caaacagtga acaggataac tcaaaagttc tattgattta ggagtatgag aatcagtaaa
    24601 tgctattact ctatttaatt tgtttgatat tttttttgta aacatttcaa ttggttttat
    24661 taaagactct actctaggag agtataatgc accttgtctt gcaaagccat tattaacatc
    24721 aattataaat aaagcagttt tactcaaatc ataattttct attttttcta ttggtagatt
    24781 atctaaatta ctctttaaag cttcaagttc atttaataag ttatccatag ttatacctcc
    24841 aagataaatt taataaaatt gtacatatta attatataaa agtcaaggag tacaaactat
    24901 tgtataatta gctgtattgt tttgagtgta aaagatttga agcaatatct ggatagttag
    24961 taaaaatacc atctacattg agttttagac agtgtagtat atcatcctct tcatttacag
    25021 tatatacatt gacaccaagt agatttttgt gacaaagttc aattagagat tcatttacta
    25081 aaactagagg tggatgaagg taactattac ccagaaattt agcaaaattg actacattgt
    25141 ttataggtaa ataacacaat aatcctgttt ttacactagg gtctaattta tgaaagtttt
    25201 ttaagctatt gctgttgaaa ctagatataa gaactctatt tttcatatta tactttaaaa
    25261 taagctctaa aacgtctttt tctatattgg gatagtttat tttgtcagtt tttagttcta
    25321 tatttaaaat aaggtctgta ggtgaaatta gaattaatac ttcttctaaa gttggaattt
    25381 tacattcttt attgttttga tatccttcaa aagatgagtt tagagttttt aattttctta
    25441 aagtaaagtc ttttacaaaa ccatgtccat taaaagttct atcaaccttt tcatcatgaa
    25501 taactacaat ttttccatcc ttagttctgt ggacatcaag ttctattcca tatatatcca
    25561 tatacaaaca ttttttaaaa gctagaatag tattttctgg atactttcca ctaaaccccc
    25621 tatgagcata aatattcatt tatatggttc cctcctataa gtataactta tcttataaaa
    25681 atttaattaa tataatatat catattc
//
LOCUS       DAMJWO010000064        24766 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.065, whole genome shotgun sequence.
ACCESSION   DAMJWO010000064 DAMJWO010000000
VERSION     DAMJWO010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24766
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.065"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(54..569)
                     /locus_tag="PC366_002597"
     CDS             complement(54..569)
                     /locus_tag="PC366_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HDF2578098.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDIAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
     gene            complement(932..2002)
                     /gene="leuB"
                     /locus_tag="PC366_002598"
     CDS             complement(932..2002)
                     /gene="leuB"
                     /locus_tag="PC366_002598"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HDF2578099.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDEIGEPLPNKTVETCRKNEAVLLGAVGGPKWDKCKGDKRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVEKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     EIYNENEIRRIGKRAFEIARNRNKKLISVDKANVLESSRLWRSIMEDLAKEFEDVELS
                     HMYVDNAAMQVVKDPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLREDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEDAVQSVLNKGYRTID
                     IYNGVGNVVGTRAMGELIVNEI"
     gene            complement(2009..2500)
                     /gene="leuD"
                     /locus_tag="PC366_002599"
     CDS             complement(2009..2500)
                     /gene="leuD"
                     /locus_tag="PC366_002599"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HDF2578100.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIDEGDNIEVDFSTGVIKNITKEKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            complement(2515..3792)
                     /gene="leuC"
                     /locus_tag="PC366_002600"
     CDS             complement(2515..3792)
                     /gene="leuC"
                     /locus_tag="PC366_002600"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HDF2578101.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTMEYINSHKCSTITKDVNIYEADEDAVYDEVYEIDLAELKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAITGKISKPSEII"
     gene            complement(3749..5491)
                     /gene="leuA"
                     /locus_tag="PC366_002601"
     CDS             complement(3749..5491)
                     /gene="leuA"
                     /locus_tag="PC366_002601"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HDF2578102.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESIKGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTPQKKVIINLPSTVEMATPNV
                     YADQIEWFCKNISCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIIGIYEDCTKLMVHDRHPYAGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKMESDRIGEELSSEAIFNLFKKEYIEVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARISYMGNEQRIVGIGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEIK
                     NGDDYDAENISQTC"
     misc_binding    complement(5615..5861)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(6009..6455)
                     /locus_tag="PC366_002602"
     CDS             complement(6009..6455)
                     /locus_tag="PC366_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578103.1"
                     /translation="MSKNKFIYMNYYDNGYFKKGMTIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTDESNYKIRLRALSLEDEKKLLNIIDEKMKKFKA"
     gene            complement(6476..7195)
                     /locus_tag="PC366_002603"
     CDS             complement(6476..7195)
                     /locus_tag="PC366_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HDF2578104.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASKKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYSGNLDVQEDMLQHLDYIIASL
                     HRPCIASGTKEENTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGTRVILGTDSHICYSIGEFENAEKVLEAVDF
                     PDELVINYHEDEIIEFFDINF"
     gene            complement(7313..8587)
                     /locus_tag="PC366_002604"
     CDS             complement(7313..8587)
                     /locus_tag="PC366_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HDF2578105.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAELQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDVRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RIKAAKEDLFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNAKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
     gene            complement(8787..10154)
                     /locus_tag="PC366_002605"
     CDS             complement(8787..10154)
                     /locus_tag="PC366_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2578106.1"
                     /translation="MENSNTNLGSESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIITACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWMFGASESTIRYSMDYLNIYLIGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIILPVLGLGISPFIMQSTESLVLIALNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCFTYSTILWL
                     LLMIFPAFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIKE"
     gene            complement(10404..10868)
                     /locus_tag="PC366_002606"
     CDS             complement(10404..10868)
                     /locus_tag="PC366_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HDF2578107.1"
                     /translation="MSLRIGGNSLGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVY
                     VFSVIGSTLVSIPLILTFRHVLQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGII
                     LFVGIPLPTTGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            complement(10873..11502)
                     /locus_tag="PC366_002607"
     CDS             complement(10873..11502)
                     /locus_tag="PC366_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HDF2578108.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRMIPLKKAKEAIFYPIVDFSEEDLKKFFDDCIMKKINESMKKVIYKNKEED
                     NVIIMITASPYAYMKYFKYYGLADKVIGTEFFYENSRYKNQFIGENCKGIEKVKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKDGEVIEQINS"
     gene            complement(11536..12423)
                     /locus_tag="PC366_002608"
     CDS             complement(11536..12423)
                     /locus_tag="PC366_002608"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HDF2578109.1"
                     /translation="MKQTNTSIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLFLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSANILF
                     VVLALISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRDDAVEHRKILEDYDIENLNQMM
                     IVILSSTIVCYSLYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNENNPTDIVLKDN
                     ALKINVILWIITCLIILIF"
     gene            complement(12452..13690)
                     /locus_tag="PC366_002609"
     CDS             complement(12452..13690)
                     /locus_tag="PC366_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578110.1"
                     /translation="MDGDILMSKILKYKNEMFLFILVVITYLIITKIFFSKTTIFYNL
                     NNTYDVLLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTD
                     FNSAYGFGLICLQIITSAMSITLVFNHIKKIKMQRLTLILLTMIMIFSFPQLFMTLNV
                     ERFIYSQFSLIFFIVIANKMKGKNSYLVELAAIPLFGITISNIYLYFFNMIFEFKLKI
                     GKMLKHLITFILMAYICVVSTKSYESFMNLGNVIQYDTKFISGEPILEKIAMIIERLL
                     YSVFYFPGASIKKGLFLQNGEVATIPVILTLLALCFCVLSVIENSEKRVPKLCMGIII
                     FNLTLHGIVGYNLVNSSIMAINFSFAVIILLAYFTKALRKNEKNMYNIFLSLLLVTIV
                     ISNVNGFIEILNIGIKSYPV"
     gene            complement(14074..15216)
                     /locus_tag="PC366_002610"
     CDS             complement(14074..15216)
                     /locus_tag="PC366_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDF2578111.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLSGGTIPKYNKELSF
                     LSKDGESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHDIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANSVKV"
     gene            complement(15357..16223)
                     /locus_tag="PC366_002611"
     CDS             complement(15357..16223)
                     /locus_tag="PC366_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDF2578112.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVLR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRIGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLVGVKLGFPVIIESIVPIIISAFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEQSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
     gene            complement(16557..18104)
                     /locus_tag="PC366_002612"
     CDS             complement(16557..18104)
                     /locus_tag="PC366_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDF2578113.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVVVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMKHAPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEEVAHSF
                     LVKEGLV"
     gene            complement(18097..19233)
                     /locus_tag="PC366_002613"
     CDS             complement(18097..19233)
                     /locus_tag="PC366_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578114.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLVVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            complement(19489..20586)
                     /gene="dinB"
                     /locus_tag="PC366_002614"
     CDS             complement(19489..20586)
                     /gene="dinB"
                     /locus_tag="PC366_002614"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HDF2578115.1"
                     /translation="MKHYRKIIHIDMDAFYASIEQRDNKKLKGKPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKSSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVEVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            complement(20976..22481)
                     /locus_tag="PC366_002615"
     CDS             complement(20976..22481)
                     /locus_tag="PC366_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HDF2578116.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            complement(22743..23093)
                     /locus_tag="PC366_002616"
     CDS             complement(22743..23093)
                     /locus_tag="PC366_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578117.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKTVTSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
     gene            complement(23316..23507)
                     /locus_tag="PC366_002617"
     CDS             complement(23316..23507)
                     /locus_tag="PC366_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578118.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            complement(23626..24174)
                     /locus_tag="PC366_002618"
     CDS             complement(23626..24174)
                     /locus_tag="PC366_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2578119.1"
                     /translation="MGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDSLKKADIEPVL
                     LKDNMNIVINSAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGDAEEERLSEFI
                     NGNTLKYDFVKMPHHGRYDKLTETFLESTSPQYAVITCSEKKEPEEGVLKILERLNIK
                     TFLTSSGEVVINSDGKTLSVNQ"
     gene            complement(24317..>24766)
                     /locus_tag="PC366_002619"
     CDS             complement(24317..>24766)
                     /locus_tag="PC366_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2578120.1"
                     /translation="TIGSLNRNKARLKVAGLQEHIANQRNDFLQKLSTKLIKENDIIC
                     IEDLQVKNMIKNRKLSRLISDVSWSEFVRQLEYKANWHGRQIVKVGKFFASSQICNKC
                     GYKNEEVKNLNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
BASE COUNT         8122 a         4485 c         2566 g         9593 t
ORIGIN      
        1 ttattttttc taaatataaa atttatgttt taaaatataa aatttttatt taatcaaagt
       61 tcaatatatt ccactttttc tttcgattct tcaaaaaacc attcttcatt agaaaaatca
      121 ccttctgcaa tttgtccaat aggcattttc atatactttc cagttgctgt cactgctata
      181 tctccatttg gtagaattat ttctcctgta ccttcaaata attttctgtt ttctttagtt
      241 attcttccaa caacttttat agtagcatct gttggtactg gtttcttata tttcaactct
      301 aaagatactg ttactcccca tatttggtca tcatttatac ttacagctct tccaatagtc
      361 tcatctaata ttgcagcaga catacctcca tgaactctcc caggataact ttgatgccaa
      421 tcctttgtat tacaaattga tacaagctct ccattttcaa gttcataaaa atctgcttta
      481 agtcctagct cattttgtgt tccacaaact aaacaagatt tactactatt ttgcttcttc
      541 aaaactttat actttgccaa aaaatccatc tcctaaccga cattagtagt cgcttaatat
      601 taaataattc taaaatatat tatataatat taataaaatc cctgcaaact tctaataata
      661 aaaataggct acttcaatat gataagttta atttaaagta ttattttcca aaaaataact
      721 ttatcaaaat agaaactcaa agtagatata agcctctttt tcgctattaa aatagtaaaa
      781 atatatttga cttaatataa aaaagagtgt ctcattaact aataaagttt attttgagac
      841 acccctcata aaacaaatta tactacaata gatttttact aattctacaa gttatatatt
      901 taaattatat tattcaaatt aaactataat tctaaatttc atttactatt aattcgccca
      961 ttgctcttgt tcctacaaca tttcccacac cattatagat atcaatagtt ctataacctt
     1021 tattgagtac actttgtaca gcatcttcaa tacacttagc ttcttcttct aagttaaaac
     1081 tatgtcttaa catcatgctt acagatagaa tagttgcaat tggatttaca atatcttttc
     1141 cagctatatc aggcgcactt ccatgtattg gttcatacat accaaaacta tcttctctaa
     1201 gtgatgctga tggtaacata cctatagaac ccgtaatcat agatgcttca tcagatatta
     1261 tatctccaaa tatattatta gtcactatta catcaaattg gctagggtct tttacaactt
     1321 gcatagcagc attatcaaca tacatatgtg acagttctac atcctcaaac tctttagcta
     1381 agtcttccat tatacttctc caaagtcttg aactctcaag cacatttgcc ttatctacac
     1441 ttataagttt tttatttcta tttctggcta tttcaaaagc tctcttacca attcttctta
     1501 tttcattttc gttatatatt tctacatcat aagcattttc gataccatca atgatttttc
     1561 ttccacgttc tccaaaataa atgccccctg ttaattctct tacaacaaca aaatcaatgc
     1621 ctttctcaac tatatccgtt ctaagtggtg aagcttcttt tatactttca tacattgtag
     1681 ctggtcttaa atttgcaaat aaacccaatg actctcttaa ttttaaaaga ccagactctg
     1741 gtcttttatc tcccttacat ttatcccact ttggtcctcc aacagcacca agcaatacag
     1801 cttcgttttt tcgacaagtt tcaacagttt tattaggtag aggttctcca atttcatcaa
     1861 tcgcgcatcc tccagctaat acatattcac aatcgaatct atgattaaat ttacaacaaa
     1921 ttttatttag aacctttata ccttcatcta taatttccgg tccaacacca tcacctttta
     1981 tgactgctat attacaattc atactccact accccctatt tgcttttatt gagttaatta
     2041 agccttcatt taatataata ttttgcataa actcaggaaa tggttctgct ttatattctt
     2101 tttcttttgt tatatttttt atcacacctg tagaaaaatc tacttctata ttatcccctt
     2161 catctatgtt attggcagct tcttcacatt caagtatagg aagccctata tttatagagt
     2221 ttctaaaaaa tattctagca aaagtagaag caatcacaca ggatactcca ctttctttta
     2281 ttacaattgg tgcatgttct cttgatgaac cacaaccaaa gtttttagtt gcaactataa
     2341 tatctccttt ttttacctta gaaataaatt tatcatcaat atcctccata caatgcgttg
     2401 ctagttcttt ataatcagct atatttaaat atctagctgg tattattaca tctgtatcta
     2461 tattgtcacc gaatttaaaa acacttccat tggcaatcat aaattttacc tcccttaaat
     2521 tatttctgat ggttttgata tttttccagt tatagctgat gctgctgcta cagctgggct
     2581 tgcaagatac acctctgaat caacatgccc cattcttcct acgaaattcc tatttgttgt
     2641 tgaaatggat ttttctcctg ctgcaagtat acccatatgt ccccctagac atggaccaca
     2701 agttggtgta gaaactgctg ctcctgcctc tataaaagtg gtaatatacc ctttttctat
     2761 agcttcaaga tatacttttt gagttccagg aaatatcata actctaactc catctgctac
     2821 ttttttgcct ttcattatct cagctactac ttcaaggtct gatattcttc catttgtaca
     2881 agaacctatt acaacttggt ctatctttat atccttatct atctcatcta ctgttctagt
     2941 attttcagga agatgaggaa aggctactgt ttcttttagt tcggctaaat ctatttcgta
     3001 tacttcatca tagactgcat cttcatctgc ttcatatata tttacatctt ttgttatagt
     3061 tgaacactta tgtgaattta tatattccat agtcttatcg tctactggaa agattccatt
     3121 ttttgctcct gcttctattg ccatattaca aatagtaaat ctatcatcca tagataagta
     3181 ttctactcca tctccacaaa attccatcga cttgtaaagt gctccatcaa cacctatctc
     3241 ccctattata tgaagtatta tatctttacc acttatccat ttatttggtt tattcttcaa
     3301 aacaaatttt attgctccag gaaccttaaa ccaacatttt cctgtagcca tacctgctcc
     3361 catatcagtt gaacctacac cagtagaaaa tgctcctaat gctccatatg tgcaagtatg
     3421 agagtcagca cctataatta catctccagc agttactata cctttttcag gaagaagaac
     3481 atgctctatt cccatatctc ctacatcaaa aaaatttaca actccttttg attttgcgaa
     3541 acttcttgta aatttacatt gttctgcact ctttatatct ttattaggtg taaagtggtc
     3601 taaaaccatc actactttag tcttatcata aacatcttca attcctaatt tttcaaattc
     3661 tctaatggct actggtgatg ttatatcatt acctaaaact acatctaaat ctgcttcgat
     3721 taattgccct ttcttaactt catttaattt agcatgtttg gctaatattt tctgcgtcat
     3781 agtcatcccc attttttatt tcctcctcaa tataactttt atttattgca ttcataagtg
     3841 cattaatagc tgctgtattt atgttttccg atatacttac accaaaatag acttcattat
     3901 tgtgctctat tcctacataa gctacccctc ttgaatgtga cccttcctct aatgcatgtt
     3961 cccagtaata tctaaattta taatctttca tgccacattg ctttagtgca ttattaaatg
     4021 aatctacagg tccatttcct ataccaacaa tcctttgttc atttcccata taacttattc
     4081 ttgcagtcat ctcaatcatg ttagtatcat tagaatcatc attttcatag tttaattcat
     4141 ccattgattt tattttatac ttcttaactt tataagggct ctcaacttca atatattctt
     4201 tcttaaataa attaaatatt gcttcactac taagttcttc cccaattcta tcagattcca
     4261 ttttgactac atttccaaaa tcagaatgca tattcttagg tatcataaat ccataatctg
     4321 tttccattat ataaacagct cctccttttc cagattggct atttatcctt ataatttctt
     4381 tgtattctct tccaatatca tgagggtcta ttggtaaata tggaacttcc cagtaatcat
     4441 tatctctgtt tttcattgct atcatgcctt ttctaatagc atcttgatgt gaacctgaaa
     4501 aagcacaatg tacaagatta cctgcatatg gatgtctatc atgtaccata agttttgtac
     4561 agtcttcata tataccaatt atcttatcta tattgctaaa atctagctct gggtctattc
     4621 cttgtgtata aagattaagt cccacattta ctatatccat atttccagtt ctttcaccat
     4681 ttccaaatag tgttccttca agtctatcgg caccagccaa taatccaagt tcacttgcag
     4741 ccgtacaagt tcctctatca ttgtgagtat gcaaacttag tataatagaa tccctacaac
     4801 ttatattttt acaaaaccat tctatttggt ctgcatatac gtttggtgtt gccatttcca
     4861 ctgttgatgg aagatttatt attacttttt tttgaggagt tggtttccaa acatctatca
     4921 ctgcctcaca tatttcaagt gcataatcca tctctgttcc tgtaaaactc tctggtgaat
     4981 attcaaaagt aaattctgtt tctggatatt tttttacttc ttcattaaat aattttgctc
     5041 cttcaactgc tatatctatt atttcttgtt tactcatatt aaaaaccaca tctctttgaa
     5101 gaacagatgt agagttatat aaatgtataa ttgctttttt acatcccttt attgattcaa
     5161 atgttttttc tataagatga gccctagatt gtgtaagtac ttgtatagtt acatcatctg
     5221 gaatcatatt ctcatctatt aattttctta aaaatgtata ctctgtattt gatgctgatg
     5281 gaaatcctac ctctatttct ttaaatcctg tatcaataag cattttgaac attctgactt
     5341 tttcatttac actcataggc gttggcagtg actgatttcc gtctcttaaa tcgacactac
     5401 accaaattgg agccttaaat atttcattat ctggccattt acgatttact atttgcattt
     5461 tatcatattt tttatacttt ccacacttca tgttatttcc ccctttttct gttttttgta
     5521 ttcagtatac cttatatcga cgcaatcctg cacacttcat aaggataaat gtcaatttta
     5581 tcattagaat aaaaaaaacc tcatctctaa taaaattaga gacgaggttt tgctcgcggt
     5641 accactctat ttagctttct aaaaagctcc cttagtaata gccaatacaa taattataat
     5701 gactatattt cctataacgt ggaattactc cgattattct aagatttaaa tcttagaaaa
     5761 cagctcctag acaagttcag aactatcaac tactaaatca caccatcctt tagctctctg
     5821 aaagtttcat tgttcttact acttctattc atcacttttt taatcattta aattttctaa
     5881 atattttgat ttaatagtta ttatatacac attaaaatgt attgtcaaca aaaaaaataa
     5941 ttatctcaat tttttatttt tgataagcaa ttctataaaa catgctaact attgaaaaca
     6001 gtatgatatt atgccttaaa ctttttcatc ttttcatcta tgatattcaa taattttttt
     6061 tcatcttcca aactcaatgc ccttaatcta attttataat tagattcgtc agtgtatata
     6121 tttaatatat tttttactac ttctattttt tctattatct tataattaaa cttttgactt
     6181 tgtttagatt ttatactgaa tatacattga ttatttatta atattgaatg attatcgaga
     6241 gtaatatata cttttccctc atatttattt gaaaaatcac gaccttgttt aaatagaaaa
     6301 actgctgtta ttatacataa aatatataat attgtcgttg aatatataaa aattgtagct
     6361 aaaattataa gtgctaaaac catatatata gtcattcctt ttttaaaata accattgtca
     6421 taataattca tatagataaa cttattttta ctcaaatttt ttcactccca agattctaaa
     6481 aatttatatc aaaaaattct ataatttcat cttcatgata atttatgact aattcatctg
     6541 gaaaatctac tgcttctaaa actttttctg cattttcaaa ttctcctata gaataacata
     6601 tatgagagtc agtaccaaga attactcttg taccatatgt tttacacaat gtcaacatat
     6661 gacttacatt ttcccaagta cccgttctat gagagtttga acttaatgat gaattattta
     6721 tttctaaaag gatattttta tctttagctt tttttactat aggttcataa tctaaaggat
     6781 acctactgtc atctggatgt ccaattattt ttaccttagg tttatccata acttttaaaa
     6841 tagcatttgt attttcttct tttgtaccag aagctataca aggtctatgc aaacttgcga
     6901 ttatataatc caaatgttgc aacatatctt cttgaacatc taaattacca ctataatcca
     6961 ttatatttcc ttctattccc ctaagaatct ttacaccttg cacttcacgt ggaagcaaat
     7021 gcaaattata aaaatagaat ggatgtggtc ctcctggcat attaggtccg tggtctgata
     7081 ttcctaagta ttttatattc ttcttactcg cctcttcgac attttccttg aaagtactat
     7141 gtgcatgtcc acttattaga gtgtgacaat gtacatccat aatagacttt ttcattaaat
     7201 ttcctcctaa tattttacat aaattcgtga aaatagctaa agggctattt caaaactaaa
     7261 gctgtcataa tagacagtgt aacgttttaa aacagcccca ttttcaatta ttttacactt
     7321 ctaaatcttt aaatttatct ttaaataatt ctccaatact tcctaaagat tcctctactt
     7381 ctaggtattc tgttatatcc tcttctggct ctctagttgc ttcttttatt gaaaccaaca
     7441 ttcttttagt ctttggttta aaatcaagaa tcttaacttt aacctcatct ccaatattaa
     7501 caacattagt aactttagcc actctagtat cactcaattc agatattggt aaatacgcat
     7561 ctacaccttc tttaatttga acaaaagccc ctttttctat tattctaaga actttagcat
     7621 tgacaacatc atcaatttgt acttcttttg ctattaaatc ccaagggtca ttatttatgt
     7681 cttttaatgc caaggcaatt tttttagtct ctttatttac atccaacaca taaacttcta
     7741 cttcttgtcc ctctgaaaca acatcttcaa cactttcaac tcttgtccaa gctaaattat
     7801 ttatatgtgc taatccttca atcccaccaa tatccacaaa tgcaccataa ggcattatct
     7861 ttgtcacctt accatctctt ttttgtccaa cttcaagaga attaaataag tcttctttag
     7921 ctgctttgat acgagctttt tcttcttctc tttcttgctt aattcttgct ctttcagctt
     7981 ctttttctgc cttaatttga gctcttcttt cttctctctc tttatttata cgctcttgta
     8041 atacatctct atgagatgct acaagtctat tttttctaac atccaattct tttatataaa
     8101 cttctaagtt aagaccaaca aatttagatg tatctgtaat aaattttgta tcaagttgag
     8161 aaattggtat aaaaaatgta tatgtattgt aattagcaaa tacaccttta tctatattct
     8221 tttcaacatt tacagttatt attctatgtt catcataagc cttttgtaac tcggcaaaat
     8281 catttctttt gtcaagttgt aatttagata aagttattgt accatctttt tgagatactt
     8341 ttgttattac agcagttatt tcatcaccta tgtggtatat atcttctata tattgatttt
     8401 tttctatgtt caattcactt ataggtatta ttccatcaaa cccatagtct aatcctaatt
     8461 gtacttcatc atttctcact gcagttattt ttccagttgt caattctcca actttcactt
     8521 tgctgaatac ttgttcttgc tggtcaagta attcttgcat tgttaaatca ttttccatta
     8581 taaacatcct ttcctcttat tgattatcat atctgtaaat attataccat taatattgca
     8641 aatacttaca tttttcttac tataattttt aaaataaatt caacttcata tatttataca
     8701 ttatagaaaa tatcttatta aattaaaata caaattctaa tttttatcta ataaaatatt
     8761 ttcataaaaa atttatattg tatatcttat tcttttattg ctttaggttt tgatagaaaa
     8821 catttataaa atataaagaa agaaattgct gttatagtag cagctgttat atctgcaact
     8881 ggctctgcta aaattactgc aaaaagtttt tcattaaaga atgttgggag tataaatatt
     8941 aaaggtatta aaagtacaat ctttctaagt agagctaaaa ccaaagatat tgttgctttt
     9001 ccaagtgcta aaaatgtctg ttgacaagct atttgaatcc caaacataaa agcaccagca
     9061 aaatatattt ttatactcca actagtcata ctaagtaact gcggattctt attaaatata
     9121 ctaacaaaaa atgcaggaaa tatcattaat aaaagccata aaatagtaga atatgtaaaa
     9181 catgacaata aacacaactt aaatgtcttt tttactctat caagttgacc tgaaccataa
     9241 ttataactta ttattggttg tgctccttgt gtaaccccca tattaggaag cataagaatt
     9301 tgcattatac tgctcattat ggccattgaa cctactgcta aatctcctcc atacatttgt
     9361 aatttactat ttaaggctat aagtactaaa ctttctgtag attgcattat aaatggagag
     9421 attcccaagc caagcactgg taagatgata cttgcttttg gtatcatata cttctttttt
     9481 attttaagta tacttttctt tccaaagaga aacataagta cccaaatagc agaaacgcct
     9541 tgtgcaatta tagtagctaa tgcagctcct tttacaccca tattaaagcc aaatataaaa
     9601 atcgggtcaa gtattatgtt tattaaagca cctatagcaa ctgtcatcat tccagttgta
     9661 gcaaaccctt gggtatttat aaaagtattc atacccattg aaatctgaac aaacactgta
     9721 cctattaaat aaatatttaa atagtccatt gaatatctaa ttgtagattc acttgctcca
     9781 aacatccaaa gtaaaggctc ttttccaatc ttaaaaccta tagtcaaaag tattgctaaa
     9841 atcaccagta cagaaaaact gttactcatt attttctctg cctcatcatt gttttgctca
     9901 cccattttta tagcagctaa tggacctcct cccataccga ttaaataact acatgcagtt
     9961 attataatta ttattggaaa ggccactcca acaccagcca tagcaacttc tccattttcc
    10021 attctaccaa taaaaatcct atcgactatg ttgtataaaa catttacaat ttgtgcaata
    10081 atagcaggtg tagcaagttt aaataataat ttacccacac tttcactgcc taagttagtg
    10141 tttgaatttt ccattttaaa acctcctcaa tccaataatt aaaatgtatc actaaaattt
    10201 tattctatat aaaaatttca ttttatcagc agacaaattt agagtacttt ccctacaagt
    10261 aatactatac tatatttctt ttgccatagt aaacatttta gaactaactg aatttaaata
    10321 ctttatctca ttttttattt attattaaaa atttttcaca tgtactcata aaaaaactat
    10381 ccaagtatat tacttagata gttttatatt atatgtaaag aaagagctga aactataacc
    10441 cctgataaca aattgccaag aaatactccc ataaaagcat cttttattct catttttaat
    10501 atggaagcta tagcagatgc agtccatgtt cctgtagttg gcagtggtat acctacaaat
    10561 agtattatac caattatcga aacacttttt aatttcttca ttcttgagtt tatttttcta
    10621 tcaattacat cagcaatccc tttaaatagt ttcttccctc ttaaaaattg taatacatgt
    10681 ctgaatgtca atatcaaggg aatcgatacc aatgtagaac ctattacact aaatacataa
    10741 acccatatag gatttaagcc cattgcaata cctataggaa tggctcccct caattctgtt
    10801 acaggaacca tagataaaat taatatgtgt aaatatccca aactattccc tcctattcta
    10861 agtgacatta agttatgaat ttatttgctc tataacctca ccatcctttt tactaactaa
    10921 aaatgcattt ttagtcaatg aaagcattgg taaatcactc ttagagtctg aatatgcata
    10981 tgaattttca taatcaatct ctatcccaag tttacctaat acagccttta ttctttttac
    11041 tttttcaatt cccttacagt tttctccaat gaattgattt ttatatcttg aattttcata
    11101 aaaaaactcc gtgcctataa ccttgtctgc aagaccataa tacttaaaat atttcatata
    11161 tgcatatgga gatgcagtta tcataattat aacattatct tcttctttat ttttgtaaat
    11221 gacctttttc atagattcgt taattttttt cattatgcaa tcatcaaaaa acttttttaa
    11281 atcttcttca ctaaaatcta ctattggata aaagattgcc tcttttgcct tcttcaaggg
    11341 tatcattcta attaaataca taaatagaat aaaaataatg tatggcaact ttataatagt
    11401 tttaaaggtt ttatttttta aagagtaaat aaaaaaatct atcatgctat cagtatttat
    11461 aacagtataa tctacatcaa gtaataatac actttttttc ataagtattt ccccatccta
    11521 tcactaaaaa tatcactaaa aaatcaatat tattaaacat gtaattatcc ataagattac
    11581 gtttattttt aaagcattat cttttaggac aatatcagta ggattatttt catttgtagt
    11641 gttaattata taattatatc taagtacacc ataaactaca aatattgttg taaatatcat
    11701 atgtggcttt tctggattac ttgtagaata caatgaataa catacaattg tagaacttaa
    11761 tataactatc atcatttgat ttagattttc tatgtcataa tcttccaata tttttctatg
    11821 ttcaactgca tcatctctta gagtttctat ttctttttta cgttttccaa gagctaagta
    11881 cagagataag aaaaatgtac ataaaattat ccaatttgat aaactaacac ttatggctac
    11941 acatcctgca taaaccctaa gtataaaacc aagagatatt gaaaacacat ctaatagtat
    12001 tatattcttt agtttaagag aatataatat attgtttatc aaatagagac taagaattat
    12061 agaaagatta aaactaacaa ctgttgataa acagactgaa attaaagcta atactacaaa
    12121 tagtatatta gcactttttt tgcttattct tccacttgcc actggtctat tacatttttt
    12181 aggatgtttt ttatctttat ccatgtctat agcatcattc agtgcatata ctgatgatga
    12241 cattaggcaa aaacacacaa acgcaataaa cgtatttaaa aataaattta tatttagtat
    12301 gttgtttgaa aaaattatag ctgaaaatac aaagaaattc tttatatatt gctttattct
    12361 cattaacttt atataatctg aaattttagt aagaagcctt atacttgtat tggtctgttt
    12421 cataaactta ctaccctttc aatattattt tttaaacagg atatgatttt atccctatgt
    12481 ttaaaatttc tataaatcca ttgacattac tgattactat agtaaccaat aacagcgata
    12541 gaaatatatt atacatattc ttttcatttt ttctaagcgc tttcgtaaag taagccaata
    12601 aaattataac tgcaaaacta aaatttatag ccataatact tgaattgact agattatatc
    12661 ctactatacc atgtaaagtt agattgaata taattattcc catacatagc ttaggaactc
    12721 ttttttctga attttcaata actgataaaa cacaaaaaca taaagctaat aatgtaagaa
    12781 ttactggtat tgtagcaact tctccatttt gcaaaaataa ccctttttta atacttgctc
    12841 caggaaaata aaaaaccgaa tacaataatc tctctataat cattgcaatc ttttccaaaa
    12901 ttggttctcc acttataaat ttcgtatcat actgtattac atttccaagg ttcataaaac
    12961 tctcataaga cttcgttgaa actacacaaa tatatgccat taggataaat gtaattaaat
    13021 gttttaacat ttttcctatt tttaatttaa actcaaatat catattaaaa aaatacaaat
    13081 atatattact aatagttatt ccaaatagag gaatagctgc taattctact aaataagaat
    13141 tttttccttt catcttattt gcaataacta tgaaaaatat taatgaaaat tggctatata
    13201 taaatctctc tacatttaaa gtcataaata actgtggaaa agaaaatatc attatcatag
    13261 taagtaaaat taaagttaat ctctgcattt ttatcttttt aatatgatta aagactaaag
    13321 ttattgacat agcactagtt attatttgta gacaaattag tccaaaccca taggcactat
    13381 taaaatctgt tgtcccagga tttgctattg aagtacaaaa taggtatatt ggatatgcaa
    13441 aaattgatat aattgctgaa aacaatatgt gcttactatt gtcttgactt atagcaaata
    13501 catttaaatt gaataaaacc cctgtatctg tatctaacaa tacatcataa gtattgttta
    13561 aattataaaa tatagtagtc ttagaaaaaa atatcttagt tattattaag taagttatta
    13621 caactaatat aaacaaaaac atctcgtttt tatattttaa tattttactc atcaatatat
    13681 caccatccat tcattatata ggatttgctg acacctacaa tttattcctt atatttaata
    13741 gccatcttca taatgttctt acttgtttta ttgtaattga ataactcttt atttacaacc
    13801 acaatattta ctttattgat gttataatca gtcaagtatt gtttatataa catagattag
    13861 tgttgtataa aatgagaatt tgtaagcaat attaatgtaa aatatttgaa aaactttata
    13921 taaaaatata caatgttgct tatggaatta aactataaca aattaaagca taatttaagg
    13981 agacaaaatt ataatctgtc tccttaaata ttaaaactat attttaaaac attactaaat
    14041 actatacaaa tttcaaatat agtataaaat taattagact ttaacactat tagctccatc
    14101 ttcttcccat tttttaattt cttttaatct atctattata ggtaaatgct gagtacattc
    14161 aacttcacat tttccacaag atatacattc tttagctttt gccttactat tcattgtgta
    14221 attccaatgt cctaaaccat aaactaactt tgtcatttct tcatcactct ttttaaacat
    14281 ctgcttttca ttataaaaaa gcatataggc tggggtatta ataccttttg gacatacttt
    14341 acaataacca caacctgtac atatttcgtt catattctta tttaatctag tctcaatatc
    14401 atgtatatcc tcatctgaat aaattctatt ttcgtctgca attttacatg catcatctat
    14461 atcttgtttt ttattaaacc ctatcaaaga tatacttatt tgtgaaattc ctatgttgaa
    14521 tcttaaagct gattctatag tactttcgcc atcttttgat agaaaagaaa gttctttatt
    14581 atactttgga atagttccac cacttaatgg attcattgcc acaacaccat atccattatc
    14641 aacagcatat ttggcacctt ttagcctata tggaaagttt aatatattta ttcccatagt
    14701 tacaccttca aacttatttt cacttagaat atctataacc tcatctcctg gttgatgaga
    14761 tgaaaatact atatggtcta tcaatccttc ttctttacat ttcaataatc cttcatattg
    14821 acctccaggt ctcattgcta gttcgtaatg ttccatcttt ctaatattcc aaacatgata
    14881 aaaatttatt ttagatacgc ctaatcgttc tattgatttt tttacagcct ctatagcttt
    14941 ttctgatgta tcacatgctt ttggcttttc tttagttgat acataaaaat cggtcttacc
    15001 ttcctttatc atttgtctaa aggctagtcc aaatatatct tcacttctgt catcacaata
    15061 ccctggcgct gtatcaaagt aattaatacc tttttcatac gcatatttga ctaaatcagc
    15121 attttcttga ttactttttt ctaaatcaaa ccttaatcct ccatagccaa ctactgaaac
    15181 cattttccct gtctttccat attcaacgta tctcattgta aattcctcct tagatatatt
    15241 aagacttaat ttctttatag aaaatattat accataaata atttttataa attatttatg
    15301 gtataatatt ttttttataa attatatttt tttataactt gtattttata gctaagttaa
    15361 aaactataaa aaggttcaat atggactatt acttgagcat tttcattaat ttcttcttgt
    15421 atttgtttct caattttatg tgttaaatca tgagattgct ctacgcttat aaatgggtct
    15481 accattacat gcatgtcaat ataaatagaa cttttgctac ctctacttct gatattgtga
    15541 acatccctta cctcattaaa ttcaaacaca atttctttta tataatcctc atctacagcc
    15601 actctatcga ccaaaattcc aatagatggc ctaaatattc cataagccga ataaattatg
    15661 aatgcagaaa taataatagg aactatagat tctattatta ctggaaatcc taacttaaca
    15721 ccaactaaag taaccaatac acctagagac acaaatatat cacttcttgt atgcaatgaa
    15781 tccgaaatta aaacataact atttagttta gtcccaattc tatattcata catgcataca
    15841 aaaatattta taaaaagtgt aataattaaa gcaattaaac tttctatagt tatagcaggt
    15901 acaactggat tagctattct tagcactgca ctaagaatta tcttaattgc tataacaaac
    15961 aacataccac ttataaataa actggttata atttcaaact ttttatgtcc ataaggatga
    16021 tttttatctt ttggtttaga tgcaaagaaa atacctataa gccccactat attagatgct
    16081 ccatctgaca aagaatgaaa tccgtctgct gtcatactat agctttttat ttgattacca
    16141 ataatgattt ttaataatgc tactgcaaaa ttagcaaata aaattatcca caatacttgc
    16201 ttcactttct tatagttatc cataacaaat tccccctccc ttcgattcaa taaagaaagc
    16261 tatctatcaa tatcaatcac ccagataata aaatcgtata taagcacatt tactatattt
    16321 atattcaaaa ttggttgtac ttgttcattc tatttgaaac ttaattataa ataaaaatcg
    16381 taggtatggt tttggtatac ataaaaataa gagactgtct caaaataaag ataagcttct
    16441 tttttattgt tgaaatgata aaatatattt gatttcatat aaaaaagagt gcctcatgaa
    16501 ctaaaaagtt cattttgaga cactccctta aatttttgat ataaactatt aattttttat
    16561 actaagcctt ctttaactaa gaatgaatga gcaacttctt ctggtgattt accaagttca
    16621 tccacttgat agttaagttc tctcatagtt tcttcattta tttttcctga aagcatattc
    16681 ataacttttt ctaactcagg atatttcttc aaagtatctt ctcttactaa tggtgctgca
    16741 taatatggta caaagaaatt tttatcgtcc tctaatatct taagattaaa ctttttaata
    16801 agaccatcag ttaaaaatgc atctataacc tgagattcat tattatctaa agctgtatat
    16861 cttaaacttc cattcattgc ttttacatct ttgaatttta aaccataatc tctagaaagc
    16921 cctacaagac catcttctct attttcaaac tccaaagttg gtgagaatgt aaattcttta
    16981 ccatatttag tcaaatcaga aatagtattt attccatact tttcagcagt ttcaggcatc
    17041 atagctaatg tgtaagtatt attaaatcca agagggtcaa gtaaagttaa ctgattttct
    17101 ttttccatag tatcttttac aacattatat gcttcatcag catctttaat cggagcatgt
    17161 ttcattacat ttaccaaaag tgtacctgta tagtcaacat acatgtctaa ctcaccagat
    17221 ttaattgcat taaacgcaac agatgaacca cctagattta aattcttctt aactttaaga
    17281 ttcgtatttt tttctactaa ttcagcataa acattaccaa gtataagttg ttctgtataa
    17341 tctttagaac caatagttat tgtatctttt ttacttgaaa aactagaact aaaaacaacg
    17401 aacaacattg aaacaacaac cactacagat attactttaa gtgctatata atttttctta
    17461 ggtgcttttg gatttaatcc ttttggagta actgcaactt caattttact aaataaataa
    17521 tcaactaaca gtgcaattat acatgatggg attgcccctg ctaaaatcat attattattt
    17581 acagtttgaa cccctgaaaa tactaaatat cctaaaccac cagcacctat aaatgctgca
    17641 agagtcatca aaccaacagc tgtaactgca gatattctaa ctccacccat tattatagga
    17701 agtgctaaag ggaattgtat tttaaataat gtctgatttc ttgtaagacc aataccttta
    17761 gctgattcta atactactgg gtcaatactt gttataccta tatacgtatt ttttacaatt
    17821 ggtagtaatg aataaaccac taccataaat atggctggtt tacttcctat gccaagtata
    17881 ggtacaagaa gacccaaaag tgccatagac ggaactgctt ggactaagtt tacaaatcca
    17941 agtacaaact ttctaagaga tgagattctt gaaataatta ttccaagagg aacaccaact
    18001 attatagcta ttaaaataga tgtaacagtt agactcatat gttgtattaa aagctctata
    18061 atcttatctt tttgtaatag tataaagtta aaaaaattag ccaagaacac tcacctccat
    18121 ttctaagaat tgttcactta aaacagaaag taaactactt ctagtaataa gccctaccag
    18181 tttattttca tcagaaataa ccggaatata tccaaccgaa ttacgattca ttacatttag
    18241 tatttctact aaattatcac cttcatttac atgcaaaggc tcactcgaca taatatcagc
    18301 aagtaatatt gacttatcat caatatcttt catatctttt acagtaacaa taccttttaa
    18361 tgtttttgct ctatctataa ttagtaagct atcaacctta ctcgttctca taatttctat
    18421 tccttgagtt acagttctag tggaattaac agcaatagga ttttttatca taatatctct
    18481 tgcttttata tattctggat tatcccaaac tctatcttct ccgataaaat cttttacaaa
    18541 gtcatttgca ggctttctaa gtatattttc gggagtatca tattgtgcta ttcttccatc
    18601 cttcataata caaattttat cagctatctt taaagcctca tccatatcat gcgttacaaa
    18661 tattatagtt tttttcaatt catcttgaag agaaaataat tgttcttgta aagatgttct
    18721 cgttattggg tctaaagcac taaaaggctc atccatcaat attatttcag catcagtagc
    18781 aatggctctt gcaacaccaa ttctttgttg ctgtccacca ctaagttctg aaggatactt
    18841 attcaaaaat tcatcactat caagtcctac catctcaagt agttgcaacg ttcttttttc
    18901 aatttcttca acggattttt ccttttttag gcgtggaatt agctctatat tttcttttat
    18961 tgtaagatga gggaataggc ctgtgttctg tataacatat cctatttttc ttctaagctc
    19021 tatttcattt tcctgagaaa ttggtttgcc attaatatat atctcaccag atgtaggttt
    19081 tattaatttg tttataagct tcaaagtagt agtctttcca caaccacttg aaccaatcaa
    19141 aactaccaat gtacctgttt ctacaactag agaaatatca tctaatataa cattatttcc
    19201 tatttttttt gttacatttc ttatctctat cataatttat catccccttt ttcgaacaag
    19261 caaccttctc caatattata agttgttttt ataattatat catactattt tatttatgta
    19321 aacaaagtac gatttttagg tcactatttg tctgaatatt gctacaaata taaagtattt
    19381 atatatagta tataatgtca aaaaacaaaa agtataaaaa tattcataaa ataacactag
    19441 cctcaattat atagtattaa agctagtgtt atttcattta aacaaaactc acatttgaat
    19501 actatccatg tattcaaata atgtaatatc tttataagtt tcttttttat cacttaagtt
    19561 tgatattgta actcccaata gcctaatttg ttttccatta acctcaacat ttctcaacaa
    19621 attatctaca ccacttctta tatcattata ttcgtcaata tagtgttcta aactaaggct
    19681 tctagttatc tttgtaaagt cctcatattt aatttttaat gttaatgttt ttccaaactt
    19741 ctcagagctt tttaatctat gacatacttc ttcacaaagt tcatcaagaa tgttgcgtgt
    19801 ttcttcttca tcaatatcca aattatgact taatgtagtc tcagccccaa cagattttct
    19861 aaccctattt ggttccactg gtctatcgtc tattcctcta gcaaatttat ataattcata
    19921 acctcttttt ttgaatatat tttcaagttc aaataaattt aaacacctta aatcatatcc
    19981 agtttttata cctaaatttt taagagtatt tgaagtaact tttccaacac caaaaaattt
    20041 attcacaggt aatttatcta aaaagtcctg ggcattttct tcggttatta cagttaaccc
    20101 atttggcttt cttaagtctg atgcaatctt agcaagaaac ttattgtatg acacaccagc
    20161 tgaagaagta agaccaactt ctctaaatat atcttttttt atttgctttg ctatctcaat
    20221 tgatgaatca atattttttt tattttttgt tacatctaag taagcttcat ctaaagataa
    20281 tggttcaact aaatccgtgt atctataaaa tatatctctt atttgctctg acacactctt
    20341 ataaacatca aatctaggtc ttacaaaaac tgcatatgga cacctattgt aagctacagc
    20401 tgatggcata gctgaatgga taccaaattt tctagcttca taagaacacg ttgcaaccac
    20461 acctcggctt tgtggatttc caccgacaat aacaggtttt ccttttaatt ttttattatc
    20521 tctttgttct atagatgcat aaaaagcgtc catatctata tgaattattt ttctataatg
    20581 tttcattatt atcacctttt aaagtataaa tagattaatt ttatttatat tactttttaa
    20641 ttataccaaa cttatgtttc tttttggtat tttttcatta ttttctttat atattcatat
    20701 tttccataaa taaaaccatc tataatccat taacttcaat ataatttata aaaaatcctt
    20761 aaaaacactt gcaaaaacta tataaaagct ttacaatagg tattccaagg aactaaattt
    20821 aaaattcctt atggataaca gtatatatat ttaatttatg ggatgtttta aaaacaaaag
    20881 actgtcttat acaagacagc ctactgattt tattataatt gtaatggact gctcaaacta
    20941 ttactttaaa acagcccata tttttttata taattttaac tatagtaaag attttgtgaa
    21001 ggatattctg ggtcacaagt tacatctata ccaagctttc taaatgtttg ttcatcatct
    21061 ctatttaata tagtagtaga atgagcttga caccctttta ataatgctaa cttttccata
    21121 gcaaactgtg cagttggatt agttacagca caaatactaa gtgcagttaa cacctcttgg
    21181 caactaagtg aaacatttct actagctaaa gtctttgttt ttaagtttat gataggttct
    21241 aatattacag gtgatattaa gtgcatatca tcagatatat tggctaaatg tttaatggca
    21301 tttaatacta ctgctgctgt tccattcatt aaatcagaac ccttaccagt taatattgta
    21361 ccatcttcta attctaatgc aactacagga caagtatcat tcttgtcggc actttctttt
    21421 aatttattac tgtaatttct agcaggtaat acaacatttc tatcttctgg ctttaagtta
    21481 agctcttcca taatcatttt cattctatca taagcgcctt tatcaacttg tcccttttta
    21541 tactcacagg cagttttaaa gtatcttctt attatttctt ctatagaagc ttttcttatt
    21601 acttcatcat ctattattcc aaagccaact ctattaacac ccatatcagt tggagattgg
    21661 aaaattgatt cttttccagt tatcttttct attatttttt taagcactgg aaataattcc
    21721 aaatctctat tgtagtttac tgacatttca ccatacgttt caaggtggaa tgaatctatc
    21781 atattcacat cttttaaatc aactgtagct gcttcataag ctatattcaa aggatgtttt
    21841 acaggtacat tccaaactgg gaatgtctca aacttagaat atccaactac attacctctt
    21901 ttattttcat gatacaactg acttagacaa gtaccaagtt ttccactatt aggtcctggt
    21961 gctgtgacta ctactattgg ctttgtagtt tctatatatt catttgctcc atatccctca
    22021 tcactaacta tagtctcaac atctgacgga tatccctttg ttggataatg cttataaact
    22081 ttaattcctc tacgttctaa tttatttata aatacagttg tagcaggttg tccttcaaat
    22141 ctagtaatta ctacactatt tacatctagt tcataacctc ttaaatcatc tattaatctt
    22201 aaaacttcca tatcataagt gataccaaag tctcctctta ttttgtttct ttctatatct
    22261 cctgcataga cacaaattac aacttcaact ttttctttca tatgttgtaa tacttttatc
    22321 tttgcatttt catcaaatcc tggaagtact ctttttgcat gaaggtctcc catcaatttt
    22381 cctccaaact ctaaataaag tttgtcaaaa ttatttactc tttctaagat gtatttagac
    22441 tgctcttcta aatatttttt gtggtcaaat cctactttca tcttaacacc tcactaaatt
    22501 aaatttcttg ttgataacag tatatttata tatatttttt tagtaaaaca tcttataaaa
    22561 aaatgttaat actttttcac tcaaagtaat attatacaat taagattaat ttttttcaag
    22621 atagttttat ggtaaataag atatacctaa tataactaat aaaataagaa tattatattt
    22681 ttatatataa gtataatatt ctcaccttaa cattaattta tttcaatatt ttcatatatc
    22741 ttttattcta aattcaatac ttttctaata tcttctatac cttgataaac ttcttgttta
    22801 gaaaaattca tagcttctaa ttcttcatca gtcttttcca taagcatagt ataaaattct
    22861 attgctatat actgcatatt ttcactagtt acagtcttag ctttatcaaa taaaatttct
    22921 tctgcttcgt ttacatttcc ctgaaaaact aatcttttta aagttataag tataacttct
    22981 tcttctgtat tatacactaa atctttttct tcatattcac tgtatttttt tcccaataaa
    23041 agtcttgcaa ccataagttt tatctcattg aaaatcttat ccactatagc catttttaca
    23101 tctcctataa ataaatttta ttttcttttt aattatatca gactttattg taaaaattat
    23161 tatatgtaaa tgaaataatt caaaaataaa ttctaacaat aaaaaaaaga aggtagcggg
    23221 ggatttccga ctaccttcaa acactagatt gtgattggtt tggtatttta tttataccca
    23281 ccataagctt tattaaatca tctaaattga tttttttagc atccacatcc tccatcaaaa
    23341 acgtcaccac attcacaaag tattaataat aatattaaga aaggtatcca tgcacataag
    23401 tccatttcag cccaacaatc ttggaatgct aagaataaga agaataatat tattatccac
    23461 caagcacatc caccaaatcc gccttcacca aaaaatctat ccaacataat atgttacctc
    23521 ctagtcattt tgtatgtgga gtttcagctc ctaaaatata ctatgtttaa ggggtaatat
    23581 ttgctaatga tttttttaaa ttttttttag atattttaaa aaaaattatt gattcacact
    23641 caatgtctta ccatcactat tgataactac ctctccacta gaagtcaaaa atgtttttat
    23701 attcaatctt tccaatattt ttaaaacacc ttcctctggt tcttttttct ctgaacatgt
    23761 aataacagca tattggggtg aagtagactc taaaaatgtt tcagttaatt tgtcatatct
    23821 tccatgatga ggcattttaa caaaatcata ttttaaagta tttccattta taaactctga
    23881 caatctttct tcctctgcat ctcctgcaaa taaaaactta tgtgctccat agcttatatt
    23941 agtgattatt gaataatcat ttgaactctc gtacttgctt tttgaagccg gatgtatgtt
    24001 tatttctgca ctattgatta caatattcat attatctttt agtagcactg gttctatatc
    24061 agctttttta agtgagtcaa tatattcatc atattgctta ctatctttct tataatttgc
    24121 ttgtataata ttctttactt taacactaga taacacacta tctactccac ctatatggtc
    24181 cttatctaaa tgggttaaac tgaacctcct atgactaaag tcacagggtt cctgcttcat
    24241 agaattttgc atactaacat atgtcttact aattctccac aggctatccc cgtagttcct
    24301 acggttctta catacgttat ttattttgaa ttgttattag tcttaatcct tcttttaata
    24361 tatttatact tgcatttata tctctatcgt gagtttcatt acaactagga caaatccatt
    24421 ctcttatatt taagttctta acttcctcat ttttataccc acatttattg catatttgtg
    24481 aacttgcaaa gaatttgcct acttttacaa tttgtctacc atgccaatta gccttgtatt
    24541 ctaattgacg aacaaattct gaccatgaca catcagaaat taagcgagat agtttacgat
    24601 ttttaatcat attctttact tgtaaatctt ctatgcaaat aatatcattc tcttttatta
    24661 atttagtaga tagtttttgt agaaaatcat ttctttgatt ggctatatgt tcttgaagtc
    24721 ctgcaacttt taatcttgct ttattcctat ttaaactacc gattgt
//
LOCUS       DAMJWO010000065        24497 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.066, whole genome shotgun sequence.
ACCESSION   DAMJWO010000065 DAMJWO010000000
VERSION     DAMJWO010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24497
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.066"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(428..604)
                     /locus_tag="PC366_002620"
     CDS             complement(428..604)
                     /locus_tag="PC366_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578121.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     TCLHQVLLLVSRYN"
     gene            1179..2201
                     /locus_tag="PC366_002621"
     CDS             1179..2201
                     /locus_tag="PC366_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578122.1"
                     /translation="MVNWEIKKLAKSKSMFISLGILVLILMISIFITPVLETERYYID
                     KEKGCIEDTRSGIDIGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNE
                     YKDISFWKVFNYRVTNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALK
                     SKIFVALLVPLVIYSVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKY
                     VILNIGIELLMFEGWAMIAIFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLS
                     VVSNVNYYDLIFGFNKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGAMSLCFLVIK
                     SDYISR"
     gene            2215..3102
                     /locus_tag="PC366_002622"
     CDS             2215..3102
                     /locus_tag="PC366_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578123.1"
                     /translation="MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQILYNGEDIFKMDANYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRVGIAQVLLNDPKIIVFDEP
                     TAGIDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKD
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDIDSVVLRIVSEDIPSGDNIQPVQ
                     AKFEDVYMFYFDLEDAREV"
     gene            3108..3881
                     /locus_tag="PC366_002623"
     CDS             3108..3881
                     /locus_tag="PC366_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2578124.1"
                     /translation="MMYLVKAEMIKILKSKSVWIIWLFLIFLGFLLIRKFDVLDTYAD
                     IFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNEPIHNLWYFGNSNLNLTVIQMYIIVILTTIFAS
                     FIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     MVRYNVPSILIVFSIVISIILMIVLTKITYENFTSSKRF"
     gene            3993..4718
                     /locus_tag="PC366_002624"
     CDS             3993..4718
                     /locus_tag="PC366_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012450879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2578125.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFK
                     SINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDVQNESKNLNKNEEKIISFGPYILNESRAELIKDG
                     KSIGLSAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLED
                     NPSKPEYILTIKGLGYKLAVKED"
     gene            4722..6125
                     /locus_tag="PC366_002625"
     CDS             4722..6125
                     /locus_tag="PC366_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2578126.1"
                     /translation="MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSG
                     NNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTP
                     KKYTPFQMVNNYKYIETKYVNFVLEKYLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
                     TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FEEDEIREYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKINLVSLVRDIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKD
                     NIEIIIKDNGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYV
                     SSEIGIGTKIIIEIKQN"
     gene            6136..6960
                     /locus_tag="PC366_002626"
     CDS             6136..6960
                     /locus_tag="PC366_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraX"
                     /protein_id="HDF2578127.1"
                     /translation="MDFFKKGISGFTIKILALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMAVEGFYHTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGAIIINNI
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIILGIFTVALLFKVTNRVI
                     TLFMILVPVPFLVEGGPIWIILGIIFYLCRGKKFSLSICYVLMCIFIFTTMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(7285..7905)
                     /locus_tag="PC366_002627"
     CDS             complement(7285..7905)
                     /locus_tag="PC366_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2578128.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKEAI
                     PGCISCASCFETGKCIRNDKVNELIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEETIMTNFIK"
     gene            8171..8503
                     /locus_tag="PC366_002628"
     CDS             8171..8503
                     /locus_tag="PC366_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2578129.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            complement(8622..9263)
                     /gene="pcp"
                     /locus_tag="PC366_002629"
     CDS             complement(8622..9263)
                     /gene="pcp"
                     /locus_tag="PC366_002629"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HDF2578130.1"
                     /translation="MKILLTGFDPFGGELINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQEHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTII
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIK
                     GGFIHIPYTTSQVINKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(9284..10216)
                     /locus_tag="PC366_002630"
     CDS             complement(9284..10216)
                     /locus_tag="PC366_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HDF2578131.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVVFAKYEEPDENFGKEQADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFDNSSQFAIGVGSIIALISALIITKAKPATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            complement(10238..10903)
                     /locus_tag="PC366_002631"
     CDS             complement(10238..10903)
                     /locus_tag="PC366_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HDF2578132.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGVATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLKQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKASTIMAVIALVVATIQFTLYDKKLNKS
                     HKK"
     gene            complement(11450..11923)
                     /locus_tag="PC366_002632"
     CDS             complement(11450..11923)
                     /locus_tag="PC366_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF2578133.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNVTIVDINNNNKIELSK
                     FDKIIIGSSIYVGSVSKKIQVLCNDNVELLNKKQVGIFLCCGFSEQADKYLKSNFPSS
                     LLESANAIGIFGSEARLEKMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLINLNS"
     gene            complement(11926..12330)
                     /locus_tag="PC366_002633"
     CDS             complement(11926..12330)
                     /locus_tag="PC366_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HDF2578134.1"
                     /translation="MKIRNKATNKKKKYVKISIALFFVFICIIIVIVSNLKPENLVVK
                     DIDINNVKNGIYTGSADNNLVKATVSVEVNNGKIQNINILKHDHLLGKPAEKITTSII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            complement(12305..12934)
                     /locus_tag="PC366_002634"
     CDS             complement(12305..12934)
                     /locus_tag="PC366_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2578135.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMTNKLYNTVESNAIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKAIMHSRMNIIFASENTNNTPSNNGIKMLDKFLSIGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLIENFLDILVGGLYNENSQQSY"
     regulatory      13299..13342
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            13443..14411
                     /locus_tag="PC366_002635"
     CDS             13443..14411
                     /locus_tag="PC366_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HDF2578136.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLHNHEKVSIIALAPLTNIAKALIKDKKAFENLDEFVSMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNIIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYEDIIDSVEGVI"
     gene            14413..14976
                     /locus_tag="PC366_002636"
     CDS             14413..14976
                     /locus_tag="PC366_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDF2578137.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDVYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPL
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQVFTDYGD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            14984..15673
                     /locus_tag="PC366_002637"
     CDS             14984..15673
                     /locus_tag="PC366_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2578138.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLRVLKNVTGKYGVLEVINSGSCFELPKDTLEKIKCIIKEKNIKKLFLESHWSYK
                     NRLKEMREYFEIPVVFKIGVETFDNDFRNNILNKNANFKTPQDVKEYFDSPCIMIGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSSIKRDEELVKWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            15800..16528
                     /locus_tag="PC366_002638"
     CDS             15800..16528
                     /locus_tag="PC366_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDF2578139.1"
                     /translation="MMFDRGKWNKLDYNELLEYMMSIKDIKYRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISQGNWKEFLEVAEDTYYEEVRLQGMVIGNINSNFEETLYYVKRFI
                     PKIDNWSVCDGFCSGLKSMKKYKENMYDILKKYVYSKNPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKCEEETFLYIKNNNLDDFTYNKMLQKI
                     IESNRVDLEKKNIIRSMKRKTRRC"
     gene            16542..17216
                     /locus_tag="PC366_002639"
     CDS             16542..17216
                     /locus_tag="PC366_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDF2578140.1"
                     /translation="MNNNEDRIDKFLELQSKGFKFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYILKDELNYNKSLDNRNLEEEKAKEYEKSKKNTISNRKKVSTKKKISNEKAL
                     SKSVEQIEFNDTGLKNAKRKQNVKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNIKP
                     KKVSNKKDVHIDDEHIDELKTTRIRIDKEIWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            17242..18078
                     /locus_tag="PC366_002640"
     CDS             17242..18078
                     /locus_tag="PC366_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578141.1"
                     /translation="MNKIVKKSISLMIILTIFIFMLTACEKDEQPDSVDIQTEDKNEI
                     KIDEGNAKVLNIGKSEIINIDEGDKVDTSTKVENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKGVEVYAYEYEAEGKIVYVNLKENTINIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEGITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            18094..18765
                     /locus_tag="PC366_002641"
     CDS             18094..18765
                     /locus_tag="PC366_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2578142.1"
                     /translation="MKVLIVEDNKILLESVVEELSKHFETEKCEDGEEALYLVNQNIY
                     DLVILDLMLPNINGFDILKKMRVNNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            18755..19987
                     /locus_tag="PC366_002642"
     CDS             18755..19987
                     /locus_tag="PC366_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2578143.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDVGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKVNLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIALELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSIDINVT
                     SDVDIGTTFELSIPKKLK"
     gene            20137..20454
                     /gene="trxA"
                     /locus_tag="PC366_002643"
     CDS             20137..20454
                     /gene="trxA"
                     /locus_tag="PC366_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDF2578144.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            20471..21349
                     /locus_tag="PC366_002644"
     CDS             20471..21349
                     /locus_tag="PC366_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2578145.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SIDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDG
                     VFVIKDSTAPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            21619..21987
                     /locus_tag="PC366_002645"
     CDS             21619..21987
                     /locus_tag="PC366_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2578146.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIKKCCKRREK"
     gene            21990..22361
                     /locus_tag="PC366_002646"
     CDS             21990..22361
                     /locus_tag="PC366_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HDF2578147.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTAVDAVVVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(22505..22960)
                     /locus_tag="PC366_002647"
     CDS             complement(22505..22960)
                     /locus_tag="PC366_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578148.1"
                     /translation="MNINTVQGDSIEVLLRQLGATRISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(22999..24264)
                     /locus_tag="PC366_002648"
     CDS             complement(22999..24264)
                     /locus_tag="PC366_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HDF2578149.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNERAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
BASE COUNT         9449 a         2700 c         3796 g         8552 t
ORIGIN      
        1 atttatataa atattgaaat ttgtctagtt atacgttttt attgaccagt tatgcagttg
       61 atattgaata ttctaaatat tggtgttatt ttataggtgg tttaaacata ttagggggat
      121 tttatatatg atttgtatga tttatagaga atgtataaaa tagtaaaggt ttagagcatg
      181 tttagtggat tgcagaatat gcatatagaa tgattcttgt aaattaagtt agacatagga
      241 aatatataat ttgtattgga tgattgattt tatggtgtat gcttttaact tctataatgg
      301 gaaagtaaag atgtactccc aatacatctt tactttagca gaagttatag ttacttataa
      361 agtacaaaaa attatatatt tattagagta gataaatcta aaaaggtttt tctagaaaaa
      421 tttaatttta attgtatcta cttactaata ataagacttg atgtaagcag gtttcaacta
      481 ccgtttctcc atattctgat ataaaatcat ctaactgtgt atctaaaaaa ttacaataat
      541 catatgaact actgatgtaa gcagttagta tatgtgtaca tttgtctatt tctccaataa
      601 acatattatc catcccccta aaaaatttag taaaaataaa aagtcgcatt ctattagtca
      661 attaacataa tttataaaat tttttagtac tagtttctat aacttaactc cttaaggtta
      721 aatattccca gttttaccaa tttagtttta ttctacaagt atataatact agaagatgct
      781 tcattattca acatgcttgt ttgagaatag aaaatattct aaaattataa ttgtttttaa
      841 aaataagatt caagataaat aaagttatat gcaactattt aataatcttt ccataataag
      901 gacagtaggt tctattctta aaaaactcca tctttaaatt taaagaataa ctacaatttg
      961 aacaacaata aaatttccaa tcaataaaaa tatcaaaaat aataaaaata attgaaaatg
     1021 tataatttcc cagaaaaata ataaatgtaa ctccaataat aaacacacct ataaattata
     1081 aaataattta agctttattt aaggttagta ttatatttat ataagattta agttttaata
     1141 tatatgtgta attaaaatga tttaggagga gaaatatatt ggtaaattgg gaaataaaaa
     1201 aattggctaa atctaagagt atgtttatat ctctagggat attagtgtta atactaatga
     1261 ttagtatctt tattacgcct gttttagaaa cagaacgtta ttatatagat aaagaaaaag
     1321 gatgtataga agatacgaga agtggtatcg acataggtaa tgagaaattt caaaataaga
     1381 ttaatgtttt aaagcagttt tcaaatcaaa cagatacagg tgaattttct aaaaaaattg
     1441 aattaatgtc aaagaaaaaa cttgataatc taagtgtgaa tgaatataag gatattagtt
     1501 tttggaaagt atttaactat agagttacaa attcacttat aaatgtagga atgttaatca
     1561 ttatatctat aattatatcc aatatttacg tagatgaagt cgttacttcg gtaaaagata
     1621 tcatactatc atcaaaagag aagaaaaaag cattaaagtc taaaatattt gttgctttat
     1681 tagttccatt agtaatttat tctgtttatt taatgggaat atttattata acttgtatgc
     1741 aacaaggagt acctgttaat ggagacttag aatcttttag aatagtagac aatgtagttg
     1801 cattgaaaac taatttaagt ataacaaagt atgtaatatt aaatataggc atagagcttt
     1861 tgatgtttga aggatgggcc atgatagcca tatttgggtc ttttataagt aaatcttcaa
     1921 tatcttcaat aagttttttt atatttatta tatctataac taagataatg tcggtaatcc
     1981 atatattacc taaaaaatta ctttcagttg tatcaaatgt aaattattat gatttgatat
     2041 ttggttttaa taaaataata ggaaattatc taggtgatat tatgatattt aaagtgaata
     2101 tagacattgt caatatagca ataggacttt tgatggcaat attgataggt gctatgtcat
     2161 tatgtttttt agtaataaaa tcagattata taagtagata aaaggggagt taagatgaat
     2221 aaattagaaa tagaaaatct ttcaaagata tatggtaaaa aagtagcaaa cgacaagatt
     2281 acagtaactc tggaaaatgg agtttatggt cttctaggac caaatggagc aggaaaatct
     2341 acattaatga aacaaataac aacgttgata aaacctgatg aaggtcagat actttataat
     2401 ggtgaggata tatttaaaat ggatgctaat tatagaaata ttttaggata tttgccacaa
     2461 gaatttggag tttataaaaa ttttacagca aaagaatttt tacagtatat tggagcttta
     2521 aaaggtttaa ggggaaaata tttaaatagt aagataggag aattattaga tttagtaggt
     2581 ctttacgatg tgagaaataa gtctatagga aaattttcag gaggtatgaa gaggagagtt
     2641 gggatagcac aagttttact aaacgaccct aagataatag tctttgatga accaacagca
     2701 ggtattgacc cacaagaaag agctagattt aggaatttaa tagcaaaaat gtctagagat
     2761 aagataataa tactttctac tcatataatt tccgatatag aatcagttgc aaaggaaaca
     2821 ataatgatta aagatggcaa acttctaatg aaaggaacac acaaagacat attaagtcac
     2881 atggaaaata aagtatataa tgttcaagtt aaaaatgaat gtgaagttga tgatatacaa
     2941 tctaaatata aggttgtaag tattcaaagt gatattgatt cagtagtact tagaattgtt
     3001 tcagaggata ttccaagtgg ggataatata caaccagttc aagcaaaatt cgaagatgta
     3061 tacatgtttt attttgattt ggaagatgca agggaggtgt agtagaaatg atgtatttag
     3121 ttaaagctga aatgataaaa atattaaaat caaagagtgt ttggataatt tggctgtttt
     3181 taatattttt gggatttctt ctgattagaa agtttgatgt tttagatact tatgcagata
     3241 tattttacaa gatagaaggc tcaatacctc taataggttt gataatgttt ataataactt
     3301 ctggaaatta cattaaagaa tatgattcta atatgacagg tttaataaat acaactaaaa
     3361 agggaaaaaa atcagtagta ttatcaaaac tagtagctaa tggattaatt ttatctatta
     3421 ttaatatttc ttttatattg ttagtaggaa ttagaggttt tagttttttt gattttaaaa
     3481 atttaaatga accgattcat aacttatggt actttggaaa tagtaattta aatcttacag
     3541 taatacaaat gtatataatt gttatattga ctactatttt tgcttctttt atatttgcac
     3601 aaataggctt aacactttca tctatattta aatcggctgt aattccattt atactaggtg
     3661 gattgataat ggcaattcca tactttagtg taggttttat accagataaa gctataaaat
     3721 ttatgtcagt gactccaaat tggattatga tgagccaaca aatggttagg tataatgtac
     3781 caagtatttt gatagttttt tctatagtaa tctcaattat attaatgata gtgttaacta
     3841 aaataacata tgaaaatttt acatcaagca aaaggtttta actaaaaata atagtaattt
     3901 tatttatatt ttagtttaat taaaaataag ataaatgaat tttagataaa atatatgcta
     3961 atatatatgt aaattattac aggaggttgt ttatggaaaa tcgtgtttta ataatagatg
     4021 atgaagtaga aatattgaag cttttagaaa ctgtcctaaa aaaagagggc cttaataata
     4081 tatatactgc aaaaactaaa aaagaaggat tagaattatt taaaagtatt aatcctgatt
     4141 tgattgtatt ggatattatg ttaccagatg gcgaaggtta tgatatttgt aaagaaataa
     4201 gaaaaacctc caattctcca ataatatttt tatcagctaa aaccgaagaa ttagataagt
     4261 tacttggact agcgattgga ggagatgatt atgttacaaa accttttagc cctaaggaag
     4321 tggcttttag agttaaagcg catttgagaa gattaagtta ttttagtgat gttcaaaacg
     4381 aaagtaaaaa tctaaataag aatgaagaaa aaattatatc atttggccca tatatattaa
     4441 atgaaagtag ggcagaactt ataaaagatg gaaaatctat aggactgtct gcaaaggaac
     4501 taaaaatcct atctttattt gcacataatc aaaatcaaat tataagtaaa gaaaaactat
     4561 gggataaagt gtggggagaa gattatgttg gatttgacaa tactataatg gttcatataa
     4621 gaaaaattag ggaaaaatta gaggataatc cttcaaagcc tgaatatatt ctgacaataa
     4681 aaggtcttgg atataaatta gcagtaaagg aagattagaa tatgaagtgg aagattacta
     4741 gaaattttat atttacaatt gtgtttgtag ctatatcagt agtaattata aatattatat
     4801 ctatattgta tgtgatttca actaatagct tttttaaagt tgtagattct ggaaataatc
     4861 ctgaagaatt tgcacgttct tttgaaaaag atttatatga aaaagatgga gaatttaaac
     4921 tatctaagat tggagctgaa aaattagaaa aatcaaattc ctggatacag gttttaaatg
     4981 atttaggaga ggaagtttat ggagtaaatg tgccaaagga tactccaaaa aaatatacac
     5041 cctttcaaat ggtgaataat tacaagtata tagaaacaaa gtatgttaat tttgtactag
     5101 aaaaatattt aaacaaaaaa catctaaaca taatagtagg tatacctagt agagatatat
     5161 caagaataat tttaacctat tctcaaaata acattaaaaa aactttaaat aaagttatca
     5221 ttataacact agtaattgat agcgtggtag ctttaggtgt aggatattta tttagtagaa
     5281 aacttacaaa accaatttca agcgtactat ggagtattga gactatggct aatggaaatt
     5341 atagtttata tcttaaggac agaggtatat atgaagaagt ttttaaaaat ataaatatgt
     5401 tagctgatac tttaagagta aatgaagttg agagaaaaga aaatgaagag ttgagagagg
     5461 aatggctggc aaatataaca catgatataa agacacctct agcatctata caagggtatg
     5521 cagagataat taatgacaaa gattatgagt ttgaagaaga tgaaatacga gagtatacag
     5581 aaattatata taataagtct aagtatataa aagatttagt tgatgattta aatttatcta
     5641 ctcgattaaa aaataatact atagttctgg acaagaaaaa aataaattta gtcagtttag
     5701 tcagagatat aataattgat attttaaatg ataatagata taaaaatagg aatattgaat
     5761 ttgaaagtaa tgaagattta attgaagtat atgtagattc aatcttattc agaagggcta
     5821 taaccaatct tatatttaat tcaatagttc ataatagcga aggaactttg ataagtgtag
     5881 aaattgtaaa aaaagataat atagaaatta taataaaaga taatggaatt ggaataagca
     5941 aaagtgattt gaaacatatt tttaaaaaat attatagagg tactaataca ggtgagatgc
     6001 ataaaggttc aggtcttggt atggctattt ctaaagaaat aatagagatt cataaaggta
     6061 aaatttatgt aagtagtgaa attggaatag gaacaaaaat tattatagag ataaaacaaa
     6121 attaggagat atgatatgga tttttttaaa aaaggtataa gtgggtttac tattaagatt
     6181 ttagcattaa tatttatgac atttgaccat atagcagcat ttatgccaca aacaatgcaa
     6241 ataccaattt ggtttcattg ggtaggcaga atatcagcac cactgtttat attcatggct
     6301 gttgaaggat tttatcacac tagtaacaga aaaaaatata taagtagatt gtatatttgg
     6361 tctgttatta tggctatagg aaatcaaata attaataatg tattttcaca tccagaagga
     6421 gctataatta taaataacat tttttcaaca ttatttttaa tagcgattta tttacaagca
     6481 atagagttca taaagaaatt tagaaaagag aaagaaatta aatattttat tataggatta
     6541 ttgatgataa tcattcctat aattttagga atatttacag tagctttact ttttaaagtc
     6601 actaacagag ttattacttt atttatgatt ttggtaccag taccattttt agtagaaggt
     6661 ggaccaattt ggattatact tgggattatt ttttatttgt gtagaggtaa aaagttcagt
     6721 ttgagtattt gttatgtttt gatgtgtata tttatattta caacaatgtc aaatggagat
     6781 tatagtttaa aaaattctat tttacaaaat taccaatgga tgatgattgc ttctctacct
     6841 ttaatgttac tttacaatgg agaaaaaggg aagagtatga agtatttatt ttatttatac
     6901 tatccaatcc atgtatatat attgtatatc ttaggaatat acttaataaa tggtttttga
     6961 ttgtaagtga tatttttaat acaaaatgaa caatatgagg attgttttag gtctattaaa
     7021 attgttattt agatgagatt tgtagaatat ttaaatttat gagcagaaat tcagttattg
     7081 taatttcaat aacattagaa tataatatta taatttattt agaaatatat gatgttatat
     7141 atggtttggt tattaatgta ataataaaat agaggtttga tataaaattc aatacctctg
     7201 ttttagtgtt ttttatccta tatttatact tattttattt ataaattagt gttttgtttt
     7261 aattaatatt agtgcatttt ttatttattt tataaaatta gtcataattg tttcttcata
     7321 ttgtggttct ttaattccag cttttttacc tgctgatata cacttaagaa gccatgccat
     7381 gttttctcct agagttcgca tagtctgtaa tccttcttca tctttcataa catcctctgg
     7441 agtaaagcca tgtacctgat tccaatactg tgatgataca ataggcatat tgctgattga
     7501 aaaatattta tttagttggt caaatgttgc acttgcacca ccacgtctac atgacacaac
     7561 tgaagcacct aattttgtag ccatgcgact tccagctatg aaaaatagac ggtcaagaaa
     7621 agaagttaat tgaccagttg cactagaaaa gtaaacagga gaaccaataa taataccatc
     7681 aatattatcg agatcttcaa tcaattcatt aactttatca tttcgaatac attttccagt
     7741 ttcaaaacag gatgcgcaac taatacatcc tgggattgct tctttaccta aatacagtat
     7801 ttctgtttta atatcgtgtt tactcaatac tttagtaatc tcatttagtg ctgtataagt
     7861 acatccatat tggtttgggc taccgtttat caataaaact ttcattataa atttcctcca
     7921 atgaatttta tttaatagat tttctaagag atattatttt ttataaaata ggattttcat
     7981 gaatattatc aatttatata gaaatgtcta atcttagaat cctatttaaa ataactcttt
     8041 ttttagtaaa tacacctcct attataaaat tgactttcaa ttattcttac actataattt
     8101 tattataaat tattctaaaa acaagtacgc acatttttgt tcaatactaa ccaaaaggag
     8161 agtgtaatat atgagtatag actgtatatc aaatacagat ttaagtgaaa caggatttag
     8221 ttatacactt tcactgatta gtggtaaata taaaatgata attctttact gtcttgtaga
     8281 atttgaagtt gtcagatata atgcattaaa acgttatata aatactattt cctataaaac
     8341 tttgagttta tcattaaaag aattagaagc agataacttg attattcgta ctgaatatcc
     8401 tcaaatacct cctaaggtag aatatagttt atcagaaagg ggaaaatctc tgattccaat
     8461 tttagatgca atgtgtgagt ggggagagag gaatagacct taattttgta tctgtagatg
     8521 ccataaaaag actgtgagta aaattgtttg aataatctac tcacagtcta tatttaaatt
     8581 aatagttagt atttttaatt tataaaatac taaaaaattt attatgaaat ttcaccacca
     8641 atttctttta catcttcttt gtatataata caagcttcta tagctaattc taaacctttt
     8701 actatttctt ctaaagacat gaatggtgta ttttttttat ttattacctg tgaagttgta
     8761 tatgggatgt gtataaatcc accctttata ttaggatatt tcttgtctat catataaagg
     8821 attccataca tcacatgatt acaaacgaat gttcctgcag tgtttgaaac actagctgga
     8881 attttatttt cattcatatg ttttaccatg gcttttacag gtaattttga aaaatatgca
     8941 ggttcaccat cttcttttat aatagtatct ataacctggt taccttcatt atcttttatt
     9001 ctaaaatcat ctatatttat agcaactctc tcaggtgtaa tgtcaaatct acctccagct
     9061 tgtccaactg atattactat atctggattg tgctcttgaa tagctttatc tatagcttca
     9121 acagattttg tcataactgt tggtatagtt atctttatga tttctgcacc gtttatatta
     9181 ttattgaccc tttcaactgc ttcttgagct gggtttatta gttctccccc aaatgggtca
     9241 aatcctgtta acaaaatttt cattatttta cctcctaatt atattaaaat cctaaaaagt
     9301 acattactaa tatgtgggct ataattaata ccaaagcaac tggagcttga tattttataa
     9361 caatataatc atttttacat tctagcaagg ctgctggaac tatattaaaa ttagcagcca
     9421 ttggagtaag tagagttcca caatatcctg ctgttaatgc taatgctcca attatagcag
     9481 gatttccacc ttgagacaat acaaaaggaa taccaattcc tgccgttatg actgaaaatg
     9541 cggcaaatgc atttcccatt atcatggtaa atataaccat acctaataca taagctataa
     9601 caccaaataa tctgctatca gcagggacta caccagatat catggttgaa ataacttcgc
     9661 cgactccagc ctgagtaaat aaagctccta atgcaactaa aagttgtggt aacatactag
     9721 caggtcccat ttgttgaagt aatcttgagc catcttgaac tgatgtagca ggttttgctt
     9781 tagttattat aagggctgat attaatgcaa ttattgaacc cacacctatt gcaaattgag
     9841 aagaattatc aaaattagaa aggctcatag ctactactac tgcagcaaat gctaatatta
     9901 atgatggtat aaatatttta tttttaagtt tgtctgcttg ttcttttcca aaattttcat
     9961 ctggttcttc atactttgca aatacaactt gtttagaaag tgttaataaa ctagataata
    10021 ttaatattat tcctattata ttggctggaa tcaatctacc aaatatgaat ggcagtgata
    10081 taagtatcca aaataatgat gtaccatatt tcttattgtt atttatggta gtaaaagact
    10141 tatatgctat aacaatcatt aaaaatccca ttagtgcgta aaagatttcc aatgatatgt
    10201 ttataaaatt ttgcattttt attcctccta aataaaacta ttttttatga cttttgttta
    10261 attttttatc atataaggta aactggattg tagccactac aagtgctatt actgccataa
    10321 tagtactagc ctttacaata ttaagtccag ttacattgta tccaaattga gttagagtag
    10381 atgctataag taatactcca ctactacctg caaataagtt ttgaccataa aaatttccat
    10441 agttttctga tgcagcagat aatgccttta tggcttcttc atccgattct tttagttcat
    10501 cactattact taaaccagca gcttgtgcca taggattaac aagtggtctt acaaattgag
    10561 gatgtccact cattcttatt gatagagcac cagctatttg tctagctatc atgtatatag
    10621 taagtacttt tcctgttgta agtcttttta atttttctat taaagaaaca gctctttgtt
    10681 ttaaaccata tctttctaat acaccgatta ctggcagtgt taatatgaat aatgatacac
    10741 ctctgtttga gacaaaagaa tctcctaaaa ttgtaaaaat ttgattaaaa tctaatcctg
    10801 caacaattcc tgttgccact cctgctaata atacagtaaa taatgtgtca attttaagta
    10861 taaatccaat tacaactatc aatataccga ttagttttat cataaattgt tctccttcca
    10921 tttctatatg ttttaattta aatttattta atggataaag ttaaactctt tttatagtat
    10981 ttgcgttaat aggactatta ttataaaatt taataaaaaa tagggaagat gttttaaagt
    11041 atcaaagtaa ataatggttg tgtataggaa tttgagtaac aaagattata ttttaagcta
    11101 atatgaattg attttgtaag tctatggttt aagtatatgt caatatttga aataggtttt
    11161 aaattagata ttatattata aaaagagaat gtgtcaaaca tagagacaag tgtatttttc
    11221 tcttttgaaa tgataaaaat atatttgatt tcatacaaaa agagagtgtc taatgaactt
    11281 tttagttcat tagacactct ctttttgtta tgattaataa agcatatatt aagagctagt
    11341 ttcattagat ttcactaaga aaaataaaat tttgataaag tttaaagact attttgagca
    11401 atattactta taaataaaag aatttatcat agaaataatt agttttattt tagctattaa
    11461 gatttattaa aaaattatct atattatcct gtgatattct aaaactgtca taattacctt
    11521 ttgaaacagc cttcataata agtttatcta aaaatttcat tttttctaat cgagcttcac
    11581 taccaaaaat tccaatagca tttgcacttt ctaataagga tgatggaaaa tttgatttta
    11641 aatatttatc tgcttgttca gaaaagccac agcaaaggaa aatgccaact tgttttttgt
    11701 ttaataactc tacattatca ttacatagca cttgtatttt ttttgaaact gaaccaacat
    11761 atatagaact tccaataata attttatcaa attttgataa ctcaatttta ttattattat
    11821 taatatcaac aatagtgaca ttatctgata gtttattttt tagtatattt gcacagtctt
    11881 ttgtacaacc atatttactt gaatatataa taatagtatt cataattatt ctccctttct
    11941 taaagcattt tctacagctt ttcgtatagt attactgcta taagttgcag aagttatagc
    12001 atccacatct aaagactgtt gtttaataat acttgttgta attttttcag caggtttacc
    12061 taaaagatgg tcgtgtttta agatattaat attttggatt ttaccattat taacttcaac
    12121 agacacagta gcttttacca agttattatc agcacttcca gtataaatgc catttttaac
    12181 attattaata tctatatctt ttactaccaa gttttctggc tttaagttgc ttacaattac
    12241 aataataatg catataaata caaagaatag agcaatagat atttttacat attttttctt
    12301 tttattagta gctttgttgc gaattttcat tgtaaagtcc tcccactaaa atatctaaga
    12361 aattttctat aagttgagaa aaattatgta aagaatatag tttattttca acaacacata
    12421 aaacgaatcc taacaatgca cttataagca tccatgagct tttatctata ttttttttga
    12481 atattccttg ttcaattcca atggaaagga atttatcaag catttttata ccattattgc
    12541 taggagtatt gtttgtattt tcagatgcaa atataatatt cattctacta tgcatgatag
    12601 cttttgccat ctctggttca ctagaaagag tttttataaa gctagtcata atttctatga
    12661 tttgtttatc tattggtagt gatgagcaat tattcataat gtcaatagca ttactttcta
    12721 ctgtgttata aagtttattg gtcatatcgc tgataatctc tgctttgtcc ttgtagtaaa
    12781 gataaattgt agttggagaa tattctattt ttgtagcaat ttttcttatt gataaatttt
    12841 catatccatg ttggtttata atttcgatgc tagcatccat aatctttttc ttcatttctt
    12901 ctttttcatt tttacgtctt tctttgatac tcatataatc acctctttgc ttaacggtgt
    12961 taagttaatt tacactgtta ttgtataatt taattttaat actgtcaata aattattaaa
    13021 taatataagt taatatattt ttatggataa taaattaatg ttattaattg taatatttaa
    13081 gatattattg tataataata atcggtttaa atgcgccaca tcttattaaa gttggttcat
    13141 aattctaaat aaactttaat aagatacatt aaaatataat aaattctttt atgctataaa
    13201 atttatttta tagctattaa atcagatgtt taaaaatttt ttaacagtct atagttttta
    13261 agagtctata gtaagtagcc taaaaatatg attttacatc tgtacttgtt cgagaactcc
    13321 aagtataaaa aactaaggaa ttatatagtg gcagtatata attaataccc ttagacacac
    13381 ctttttgaaa gtggaaaaaa gatgtgtagt tctcctcgac cacaaatcaa ggaggataaa
    13441 aaatggaaaa gagaaaagta ataattgatt gtgacccagg aattgatgat tctttggcaa
    13501 ttcttctggc tttaaactca ccagagctag aagtaattgg aattaccaca tgttgtggaa
    13561 atgttccagc aaatataggt gcagaaaatg cactaaaaac acttcaaatg tgttcttcac
    13621 taaatattcc agtatatata ggagaagaag caccactaaa aagaaaactt gtaacagctc
    13681 aagatacaca tggagaagat ggtattggag aaaactttta tcaaaaggtt gtaggagcta
    13741 aagcaaaaaa tggagcagtg gattttataa taaatacttt acataatcat gaaaaagtat
    13801 caataatagc acttgcacca cttacaaata tagctaaagc acttattaaa gataagaaag
    13861 catttgaaaa tctcgatgag tttgtatcta tgggaggagc atttaggatt catggaaatt
    13921 gctctccagt agcagagttt aattattggg tagacccaca tggagcagat tatgtttaca
    13981 agaatttatc taaaaaaatc cacatggtag gtttagatgt aactagaaaa attgtactta
    14041 ctcctaatat tattgagttt ataaatagac ttgataagaa gatggcaaag tatataactg
    14101 aaataactag attttatatt gatttccatt gggaacagga aggaataatt ggctgtgtga
    14161 taaatgaccc tctagcagta gcgtacttta tagacagaag tatatgtaaa ggatttgaat
    14221 catatgtaga agttgtagaa gatggaatag ctatgggtca gtctatagtg gattctttca
    14281 atttctataa aaaaaatcct aatgcaattg ttctaaatga agttgatgag aagaaattta
    14341 tgtacatgtt tttaaagagg ctttttaaag gttatgaaga cattatagac tctgtggaag
    14401 gagtgatata gtgtgaaaag aaaaatatgt gtaaaaacta ttacacttat agcttttggt
    14461 atttctataa atataatagg cgcttttata gctatgggat taagattacc tgtatactta
    14521 gattcaatag gaactataat gatagcttca cttttaggac ctaaatacgc tgttgttaca
    14581 ggtgtgtttg gaagtttaat aagtggaatt acgtttgatg tgtattctct ctattttgca
    14641 ccagttcaaa tatcaaccgg attacttgct ggaatagcat ttaaaaagaa ttttttaagg
    14701 ggtttaaaaa ctccactagg agtactttta tttgctattc caacatctat aataagttca
    14761 ataatttcag catttttatt tggaggtatg acctcttcag gttcatccta tatagtgcaa
    14821 atcttgaaag tgttaggact gggagatgtt tttagtgtgt ttgtaaccca agtatttact
    14881 gattatggag ataagctgtt agcagttgtt ttagtgaatt taggattaaa tgcagttcca
    14941 aaaactttaa aggtatcatt gactggagga aaatagatag aaaatggata gatatagtga
    15001 gataacaaat aaaaatcaaa gagaaattgt tctgcttaaa ggatttcctt gtatatgggg
    15061 aaagtgttct ttttgtgatt atatagatga taattctaat ttagaagaag agatgaataa
    15121 attaaatcta agggttttaa aaaatgtaac tgggaaatat ggagttcttg aagtcataaa
    15181 ttctggaagc tgttttgaat tacctaagga tactttagaa aaaataaagt gtattataaa
    15241 agagaagaat ataaaaaaat tatttttaga aagtcattgg tcttacaaaa ataggcttaa
    15301 ggaaatgaga gagtattttg aaattcctgt ggtatttaaa attggagttg aaacctttga
    15361 caatgatttt agaaataata ttttaaataa aaatgcaaat tttaagactc cacaagatgt
    15421 aaaagaatat tttgattcac cttgtattat gattggaata aaaggacaaa caaaagagat
    15481 gatagataaa gatatagaga ttatcctaaa tacttttgaa aaagcgacag tgaatgtttt
    15541 tataaataat tcttctagta taaaaagaga tgaagagtta gtgaaatggt ttgttagtaa
    15601 gtataaattc ttggatgaaa atccaaatat agaagtttta tacaataata cagactttgg
    15661 tgtaggagat tagcattaat ttagtttaaa tttaaaattg aaaagtttct tatgtttttg
    15721 aaaaagcttc taatagttag aagctttttt tgtagagttt tatgttacaa taagaaaaaa
    15781 ggaattaagg agcaattaaa tgatgtttga taggggaaaa tggaataaat tggattataa
    15841 tgaactttta gaatatatga tgtctataaa agatataaaa tatagagatt ttaataaaaa
    15901 gcttatacct ggaacagaaa atataatagg tattagagtt cctaatttaa gaaagttatc
    15961 aaaagaaata agccaaggga attggaagga atttttagaa gtagcagagg atacatacta
    16021 tgaagaagtt aggctacaag gtatggtaat tggcaatata aatagtaatt ttgaagaaac
    16081 tttatactat gtaaaaagat ttatacctaa aatcgataat tggtcagttt gcgatgggtt
    16141 ttgttctggt ttaaagtcta tgaaaaaata taaagaaaat atgtatgata tacttaaaaa
    16201 atatgtttat tcaaagaatc catgggaaat tagatttgca ttagttatgt ttttaatata
    16261 ttatgttgat gataaacata ttaaagaaat atttgaatac tgtaataata tacaaagtga
    16321 agaatattat gttaaaatgg gtatggcatg gttgctatca atttgtttta ttaaatgtga
    16381 agaggaaact tttctctata taaaaaataa taatttagat gatttcactt ataataaaat
    16441 gctacaaaaa ataattgaat caaatagagt agatttagaa aagaagaata taataagaag
    16501 tatgaaaaga aagacaagaa gatgttgacg gaggaatatt aatgaataac aatgaagaca
    16561 gaattgacaa atttttagaa cttcaaagca aaggatttaa atttgcagag atagctcaaa
    16621 atctaaagat tagtcaaagt actttaagaa cttttttaaa taaaaaagga tataagtcag
    16681 aaaaaggtaa atacatatta aaagacgaat taaattataa taaaagtttg gataatagaa
    16741 acttggaaga agagaaagct aaggagtatg aaaaaagtaa aaagaatact ataagtaata
    16801 gaaaaaaagt aagcaccaaa aaaaagattt ctaatgaaaa ggctttaagt aaaagtgttg
    16861 aacaaattga gtttaatgat acaggtttaa aaaatgcaaa gcgaaaacaa aatgttaagc
    16921 ctaagaaaga tagaaaaata aatataactc aagaagattt agataagctt tgtgaagtat
    16981 atgattggta tttagaagta aaagattaca atataaagcc taaaaaagta tctaataaaa
    17041 aagatgtaca tatagatgat gaacacatag atgaattaaa aacaacaaga atacgtatag
    17101 ataaagaaat atggaatgat tttgaaagat tatgtagtaa ttcgaatttt gaaaaacatc
    17161 aaatacttac acaggcattg aaagaattta tgaaaaagta taaaaatcta ctataaaata
    17221 ctactatatg aggtgcttaa tatgaataaa atagtaaaaa aatcaatttc tctaatgatt
    17281 atattaacaa tatttatttt tatgttgaca gcatgtgaaa aagatgaaca gcctgattca
    17341 gttgatattc aaacagaaga taaaaatgag ataaaaatag atgagggaaa tgcaaaagta
    17401 ttgaatatag gaaaatcaga aattataaat atagatgaag gtgataaagt agatacatca
    17461 acaaaggtag aaaataattc aacatttaat atatccaatg ttgaattgat atataatgaa
    17521 tatgatgaga ataaaaaaat tatatcttcg gatagtaagg ctttgttgga tatgacttta
    17581 atgcctggga aagttgctta catagaatgt gggcataaaa cttttgtaaa gggtgtagaa
    17641 gtttatgcat atgaatatga ggcagagggt aagattgtgt atgttaattt aaaagaaaat
    17701 actattaata taagaaataa taatattaag ctagaaaata gtagtcagta tgaggtgcta
    17761 tctacatcag aacttaaaaa agtaaatgaa tcaaatgagg gaattacgta tcaagtaaaa
    17821 gtaaaaaatt catcatcaaa agatttagga aatattattc ttaagacagc agaagttaat
    17881 gaaaatggag aatatttaac agtaaatcgt gtaccatcat ataagatttt aaagccttca
    17941 gaagagacag atatagatat attgtgttca acaaaggcaa aaagtgttga aatagtggga
    18001 tatacgtatg atgatataaa agaaaaagcc aatgtggata ttgacttaaa atctcataaa
    18061 gttaagatag acaaataaag gtaggggata cttatgaagg ttttaatagt tgaagataat
    18121 aagatacttt tagaaagtgt agtagaagaa cttagcaagc attttgaaac tgaaaagtgt
    18181 gaagatggag aagaagcttt atacttagta aatcaaaata tatatgattt agttatttta
    18241 gacttaatgc ttcctaatat aaatggattt gatatcctaa agaaaatgag agttaataat
    18301 atagatacac ctgtacttat attgacagca aaagaaacat tagatgacaa agtagaagca
    18361 tttactatag gagctaatga ttatttgaca aaaccttttt atatggaaga gttagtagct
    18421 agggtatacg ctatattaag gactaatgga aagataaaag aaagaaacgg attagaattt
    18481 aaatctttat atttagatac actagaaaaa agagtgtata ttgaaaaaga agaaataaaa
    18541 cttcaaaaca aacagtttaa cttgcttgag tattttgtat taaataaagg ttcaatttta
    18601 ttaaaagagc agatttatga tagaatatgg ggaattgatt cagatgcaac tattgaaata
    18661 gtggaagtat atgtaagtaa tctaagaaaa aagctaagta aatatggata tgataaatat
    18721 attaaaacta aacgtaaggt aggatatata ttcgatgata aataagaatg tatttaccag
    18781 tactaaaaat catttaataa aaatgtatat tattgtagta ggtagttttt taataatctt
    18841 ttctatattt atatactcat attttagggg acttacatat agtggaattg atagtgagat
    18901 aaatgatgaa cttgaatata tagtctctca atttaaaaga acttcatttt tgaacccaat
    18961 aagactgaaa gatcctaaag atatggtgta tgtatatgaa gatggaagga taagttacta
    19021 tactcaaaat gaatattttg atgagttact tccagataga agactagata aaaaaaattc
    19081 gttttttaaa tacacagaaa atggatatac ttttagagaa ttaaatgtag atgtaggtag
    19141 ataccaaata cagataatta gaaatataga ttctgagatg aattctttaa gacagcttac
    19201 atctgttctt ataattggaa tattaatttc tgtaataatt acttactttg tggctgtata
    19261 tctcactaga aaagctttaa ttccaataga aacagcatgg aaaaatcaag ctaagtttat
    19321 acaagatgct tctcatgaat taagaacacc aataacaata gtttcatcaa aattagaaag
    19381 tatgttaaaa tccccagaaa gtacagtaaa tgatgaagtt gaaacaatag ctactgcaat
    19441 gaaggaaact agaagactta aaaaaatgat aactgattta ttgtctctta ctaaagagga
    19501 ctctattgtt aaagttaatt tagaagaaat agacttagaa aaattattgg aagaaatatc
    19561 agaagactat attgacattg ctgagtttca ggaaaaaaga ttcgtgttta attctaaact
    19621 gaagaataaa gttataataa cagataaaaa taaattaaga cagcttatat taattttcat
    19681 tgataatgcc tttaaatata caaaattggg tgatgagata gcattagaat taaaagaaga
    19741 tatagaggat gaggtaactt tacttataag tgacactggt ataggcataa aaaaagaaga
    19801 gatacctctt atatttgata gattttttag aagtgaaaat gtaagaaata aagatttaga
    19861 aggttctgga ataggacttt caatagctcg catgattagt ttaaacttat ctattgatat
    19921 aaatgtaact tctgatgtag atattggaac tacatttgaa ttgtcaatac caaaaaagtt
    19981 aaaataataa aaatataaaa aattgttttt agaaatgaag aatgggtata ctaattagta
    20041 taaaatataa aaagacctta taaaagtaaa tttatattta taaatttcat agtataatta
    20101 tatagggata ataaagttta ataggaggat ttaaaaatgg caaaagttat aaatacatct
    20161 gaatttagaa gtagtgttga aggtagtaag ggagtagttg tagttgattt ctttgcaact
    20221 tggtgtggac cttgtaacat gttgggacct gtatttgcag aattaggtga agagatgaag
    20281 gataaagcta gatttgtaaa agttgatata gatgagagct tagaaatagc tcaacaattc
    20341 aatgtatcta cagtaccaac tatgattata tttaaagatg gaaaaccagt agaaacttta
    20401 attggattca tgccaaagaa caaaattgaa atgcaagtaa aatcatattt ataaaaaatg
    20461 ggtgagtatt atgagatatg atatagctat aatcggcagt ggtccagctg gattgtctgc
    20521 tgctataaat gcaaaaataa gaaataaaac aattatcatg tttggtaatg ataatttaag
    20581 taataagctt gttaaagctc cttcaataga taattattta ggtttttatg atataagtgg
    20641 tgatgaatta aaagacaagt ttaaatcaca tatagatagt atggatattt caattgaaaa
    20701 taaaagaata aataatattt atgctatggg agaatacttt acaataatgt ctggaaatga
    20761 tatgtatgaa gctactactg taatccttgc aactggggta gagtatacta gaccaatcaa
    20821 gggtgaagaa gaatttctag gaagaggtgt aggctactgt gctacatgtg atgcaccact
    20881 ttatagaaat aaaaaggtag cagttatagg atataatgaa gaatctaaag aagaagcaaa
    20941 ttttttaagt gaactcactt caaagactta ttttatacct atgtacaaaa aagataatct
    21001 tatgagaagt tcagataacc tagatgattc tattgaagtt atacatgaca gaccagtaca
    21061 gatagatgga gataaacttg taaacaaagt atcttttaaa gaaaaccaca ttgaagttga
    21121 tggagtattc gttataaaag atagtacggc tccaagtgca ttggttcctg gaatagagat
    21181 tgatggcatt catattaaag ttgacaataa tatgaagact agtatagatg gatgctttgc
    21241 tgctggagat tgtgttggaa aaccctattc ttatataaaa gcagctggtc aagggcaaat
    21301 agcagcttta aatgctgttt actatttaga taaattaaag agggcttaat atttatattg
    21361 attaactttt taaagatatt tataaaaaac tgtcttgaaa taattttatt atttcaagac
    21421 agttttttat ttttaagtta ttaataaaag tattttaaaa tctatatgta attactttta
    21481 ttaataaaat tcaaagttat attagtagaa attggaatta tttataatat actccaaaat
    21541 ttaaaaataa tggttgaaaa atctaattaa gagtactata atttaattaa gtaattactt
    21601 aatcaaaacg aggtacttat ggaaaacttg gttaaaatat ttaaagcatt gagtgatgaa
    21661 actagactta acatacttat attagtatcc aagagaaata tatgtcaaaa ggggatttct
    21721 aaatatctag ggatttcaga ttctgctgtt tcacaacata taaaaatatt aaaagatgtt
    21781 gggataataa caggatataa agaaggatac tatgttttat atcatattaa taaagaatca
    21841 tttaatatat gtgtagattt tataaattct atgttaagta attctagtga aagctttata
    21901 gatgtatttg atgtaaatac aatacatcta ggatgcagta aagaatgtaa atctataaaa
    21961 aaatgttgta agagaaggga gaaataataa tgaaagtatg tataccagta gaggagaata
    22021 aaggattgga tagtaaacca tatggacatt ttggttctgc tccaattttt gttgtgtgtg
    22081 atttagaaag tggagaagtt aaatctttag ataatggaga tttagatcat gaacatggaa
    22141 aatgtcaacc attaaaagca ttgtcaggga cagctgtaga tgcagtagtt gttggaggaa
    22201 taggacaagg agctataatt aaattaaatg gaatgggaat aaaagtttac agagcagaag
    22261 gtgatactat aagtgctaat ttagacttac ttaaaaatgg aaaattagta gagtttccat
    22321 cagaccatac ttgctcacat gacggatgtg gacatcatta aaaaaaacag ctgatgaaat
    22381 atatacttca tcagctattt tttcttttaa taaatacgat tttattcttt taaaaccaaa
    22441 atttagattt ttatgttttt tgtagtatcc ttaataatat ttcaagttta caagtttact
    22501 acttttagat tttttttgta tgtttttcta tatagtcaat atcatttaat atgtcattga
    22561 gttctttatt aagtgttttt aaatcatcac catctacatt gtagtttaaa aatagttcct
    22621 ctacattatc aatgatagaa ttgacttttc tagtaacttc aacaaatgtc ttaaagttac
    22681 tactattttt agcatttaga aattttttta aatcctttga tataaatgat actatttcat
    22741 attcatcatt aaatagacct ctaccaatag gatatggttc aattctctgt aaaaaatatt
    22801 ggtctttagc attaatatta taagtataag atatttccca accgtctcct aaatcaaact
    22861 tgataaaata taatgtacta cttacttttg atattcttgt ggcaccaagc tgtcttaaaa
    22921 gaacttcaat cgaatcacct tgaacagtat taatattcat atatacacat cccctttagt
    22981 attattatac tatatttttt aaaattttat aattaaataa acagtagata taataataga
    23041 tataatcata agtggaaaac ctattttgaa atactcctta aaagagatag gatgaccgtg
    23101 tttattacct atacctgcta gtacaacatt agcagatgct cctattagtg ttccatttcc
    23161 tccaagacaa gctccaagag atgttgccca ccatagtggc attacatcaa taccttcagc
    23221 ttgcatagtc aaaataagag gaattagtgt tgcaacaaat ggaatattat ctaagaaaga
    23281 agagactata gctgataacc ataatatcaa caacattgta aatacaagat gtccttctgt
    23341 aagtccaatc aatgcttgag ccaatttgtt tattatccca acttctacta gtccaccaac
    23401 tactacaaat aatcccataa agaataaaat tgtggaccat tcaatacctg ccataatttc
    23461 atctacatct tgttttccta ttaaaagcat tatagatgct cctgtcagtg ctacaacaga
    23521 agaatctatg tggattgtac tgtgaaacat aaaaccaaaa agtatgaatg ctattaatat
    23581 aaggcttttt ataagtagag gtttatcttt aacagatttt ttttcatcta gttttaatat
    23641 tgcattttta gctctttcat tcacaacaag ttcttttcca taaataaatc taaagcatat
    23701 tatagttata gcaagtatta ctataacagc aggacctaaa tttattacaa aatccataaa
    23761 actaagattg gcagcactac caatcataat atttggaggg tctcctataa gagtagctgt
    23821 tcctcctata tttgaagcta aaatctgtgt tattaaaaat ggaactggat taagtcctaa
    23881 tatttgtgta ataactatag tcattggtcc aataagtaag acggttgtaa cattatctaa
    23941 tacagctgat aaaatagctg ttataatagc aaaacaaatc attatcttcc atgggtcacc
    24001 tttagctttc tttgcagtcc agatagctat atattcaaat aaccctgagt ttttgacaac
    24061 agctacaaat agcatcatac caactaatac accaatagta ttgaaatcta tatggcttaa
    24121 tccttcatca agtgtaagta tattgaatat tatcattaat agtgcaccac caacagctgc
    24181 tacggatctg tttacctttt ctgtaataat agctgccata actattaaaa atatacatat
    24241 agctattatt tgttgaaatt ccataatata agtacctcca tttgtattat tttgtgccta
    24301 atgctagtac tatatatagt attacttttt tattgttttt tcaatggatg tatgaaagta
    24361 tattatttaa caaagttttt gagaaattga cagaatttaa agaaaatttt tgttatttaa
    24421 ataaatttta aaattattcc attgataata atattaaacg acaaacgaaa aaatataccc
    24481 tttaaactag aatttat
//
LOCUS       DAMJWO010000066        24368 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.067, whole genome shotgun sequence.
ACCESSION   DAMJWO010000066 DAMJWO010000000
VERSION     DAMJWO010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24368
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.067"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            97..3045
                     /locus_tag="PC366_002649"
     CDS             97..3045
                     /locus_tag="PC366_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2578150.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEAISSRLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKEIQDSGDL
                     KLDKESDDKKEEIINNRENKDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFAVESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADENKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETRLTHKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKLKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIIGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LSSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPLEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRDMSEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEATTIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGINIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKCNNTKVDFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKAKLNQINNLIDTNQIGETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKKPIVWSKSKVKIILLLAVDQKCFNPLSTLLSFIETDEFKKIKNIKDRDFIRE
                     MILDGVNENN"
     gene            3023..3487
                     /locus_tag="PC366_002650"
     CDS             3023..3487
                     /locus_tag="PC366_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2578151.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKESYIQ
                     AVVAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            3600..3902
                     /locus_tag="PC366_002651"
     CDS             3600..3902
                     /locus_tag="PC366_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2578152.1"
                     /translation="MGVTNVTKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLINDVLEELEL"
     gene            3964..5328
                     /locus_tag="PC366_002652"
     CDS             3964..5328
                     /locus_tag="PC366_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425524.1"
                     /note="with GatAB forms a phosphoenolpyruvate-dependent
                     sugar phosphotransferase transporter for galactitol;
                     subunit IIC forms the translocation channel and contains
                     the substrate binding site; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDF2578153.1"
                     /translation="MEGLYMEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGL
                     TVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALI
                     IPIGLVVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMVIV
                     LVMADLTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQ
                     KKFGLFGEPLIMGSVIGVIIGIAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLP
                     VSEAAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVL
                     PFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFK
                     MPEGATMISSICDGANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKL
                     SIEE"
     gene            5363..5836
                     /locus_tag="PC366_002653"
     CDS             5363..5836
                     /locus_tag="PC366_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578154.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYINFNLNIYSL
                     LIIVCTYGIFNTFISSSNPKKIIIDSKCIHFTSFMTTHKYEIKDIEKIRIREFYNKKI
                     YLKINDGDLFKGRYWIRTNMFNNSIALYSYFIELEECLYPDSLRFRNKKFENKNI"
     gene            6008..6658
                     /locus_tag="PC366_002654"
     CDS             6008..6658
                     /locus_tag="PC366_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HDF2578155.1"
                     /translation="MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDHLYIYKHREDINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTFKKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            6832..7764
                     /locus_tag="PC366_002655"
     CDS             6832..7764
                     /locus_tag="PC366_002655"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDF2578156.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEDSIFIG
                     KNQNPYQEVHHDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKDRQLHEIDFLEHT
                     KFMQKMLSTLGLDVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSNKATESNATKSVSSKVTNIKFLLEKDINYFLDYCVEYLKSNIKNIKELELDEED
                     IKSVYNIGEDKYRKIEWTYGKTPKFQVVLPFNNESKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            8038..8751
                     /gene="ispD"
                     /locus_tag="PC366_002656"
     CDS             8038..8751
                     /gene="ispD"
                     /locus_tag="PC366_002656"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HDF2578157.1"
                     /translation="MYSVIIVAAGSGRRMNLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKKLDENCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVQETPERNLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            8748..9233
                     /locus_tag="PC366_002657"
     CDS             8748..9233
                     /locus_tag="PC366_002657"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HDF2578158.1"
                     /translation="MRIGLGYDVHKLTENRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    9328..9536
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            9600..11315
                     /locus_tag="PC366_002658"
     CDS             9600..11315
                     /locus_tag="PC366_002658"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDF2578159.1"
                     /translation="MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFDRCGLENSPVQADSGAIGGSTSAEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNLASQKEEMKELEEVHTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDQCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            11437..12882
                     /locus_tag="PC366_002659"
     CDS             11437..12882
                     /locus_tag="PC366_002659"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDF2578160.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKTKGVAVEVDDRDNYT
                     TGWKFNEWEMKGAPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            13322..14803
                     /locus_tag="PC366_002660"
     CDS             13322..14803
                     /locus_tag="PC366_002660"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HDF2578161.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHSEGVILDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSVERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLVEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEITEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALREKIEKTEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            15024..15179
                     /locus_tag="PC366_002661"
     CDS             15024..15179
                     /locus_tag="PC366_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578162.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            15324..16721
                     /locus_tag="PC366_002662"
     CDS             15324..16721
                     /locus_tag="PC366_002662"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HDF2578163.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKIFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDDFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            16706..17119
                     /locus_tag="PC366_002663"
     CDS             16706..17119
                     /locus_tag="PC366_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HDF2578164.1"
                     /translation="MEKDIKMEKTELVTMSPLVLAYLGDTVYETYIREYLIRQNTQRK
                     VNDLHKLAIKYVKAKAQATIIHEIEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKH
                     ATGFEALVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            17226..17321
                     /locus_tag="PC366_002664"
                     /pseudo
     CDS             17226..17321
                     /locus_tag="PC366_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452247.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase (FAD)"
     gene            17627..18457
                     /gene="thyA"
                     /locus_tag="PC366_002665"
     CDS             17627..18457
                     /gene="thyA"
                     /locus_tag="PC366_002665"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003518901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HDF2578165.1"
                     /translation="MSLADKIFIDMCNNILENGVSSDGEVVRAKWDDGQPAHTIKKFC
                     VVNRYDLSKEFPILTLRPTNLKAAIDELLWIWQKKSNNINDLNSRIWDSWADETGSIG
                     KAYGYQIGQKHKYKEGEFDQIDRVIYDLKYNPYSRRIITNIYNHNDLNEMNLYPCAYS
                     MTFNVTGNRLNAILNQRSNDILVANNWNVTQYAILVHMLAQISDLEVGELVHVIADAH
                     IYDRHIPLVKELINRESYDAPKLIINPNIKNFYDFRVEDFTLENYKSGPQIKKIPVAI
                     "
     gene            18470..18964
                     /locus_tag="PC366_002666"
     CDS             18470..18964
                     /locus_tag="PC366_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDF2578166.1"
                     /translation="MKVIVAVDLNWGIGYGGKLLQSIPEDMKFFKEKTVGNVVVMGRE
                     TFKSLPGKKALKDRVNIVLTRSKSFNDDRLIVCNSIDETLKELQKYENDKIFIIGGET
                     VYKQFLPYCNELYVTKIQKTYEADRFFPNIDIMSNWDLIKESEVKEYNNIRYVFSTYI
                     NNSL"
     gene            18991..20367
                     /locus_tag="PC366_002667"
     CDS             18991..20367
                     /locus_tag="PC366_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HDF2578167.1"
                     /translation="MKKDIFVNRVSNALENDRGAVFVGSGISFSSTEVDWFKLLEPLV
                     NELDITLDNKSDDLPMIAQYIVNNYSGNRGPLVNEISKTFNRKFKLNKYHKYLATTKL
                     STIWTTNYDMLLEDAFYDFDTSVKVSDDSITRNRLEYDVEIIKMHGCISRSDWNEIVI
                     TQEDYDDFSINKPAISQRLSEDLINKSFLFIGYSYRDPNIRNIMINARRLSKKHTQQH
                     YIILKKLKDSDSNITQDDVVRQELWCNDLKRLGISTLFIDEYSELEELLREISQKSRG
                     KTVYVTGSHKESNMNARKLGTKLAKHKDITLLSGQSSGIGSEVVAAFTEECIKSKEDI
                     INRMKIFPNPYSADEKYSDDITLIPDLKKCRTKMLNSTQVVVVFSGGIGTEAEIDVAI
                     KQNCNIIPVITCKEDRENPAIKKILNYSDNMKNIEIKDATYYNKIVDEDGVVTMEEIY
                     ICISKIMN"
     gene            20343..21443
                     /locus_tag="PC366_002668"
     CDS             20343..21443
                     /locus_tag="PC366_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HDF2578168.1"
                     /translation="MHIKNNELKHDIIKLKKRNGFIEVGKDKKTLVNCLIGANELEDY
                     KYEIKKIDCILNISEKPDIVSDLSTKRRKISESIWYKIVKDTPFVSATLPIYLVSKNN
                     NKIDSNELLDIIIEQMENGVGMITIHPTANKQIFEDSKNRMVPVTSRGGGMVIQDLIS
                     KNFSEDNVYLKILPEIIKYAQKHNVCISLGATFRSGNIFDSNDRAQITEIKSQIELAK
                     RIYKSNVGVIIESPGHSRPSDIIKISSILKKEGFPIMPLGPIPTDIAIGMDHIAAAIG
                     ATIMGIEGCANIISTVTREEHTGGRPSIESTVESIRTAKIAAHIIDIHQMNDINLDMS
                     VSKSRAKSNTCIFGKDTRYCDRCRELCPLCIR"
     gene            21486..21911
                     /locus_tag="PC366_002669"
     CDS             21486..21911
                     /locus_tag="PC366_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HDF2578169.1"
                     /translation="MHRIASFSQQSQRYVKLEQFEYIIPPEIEKIEKAKELFINSMKK
                     YQEDYDKLVEILFENHYNKLIKGGKNEKTSKRQVEKKAIEDARYVFPNACETKMVFTI
                     NARSLFNFFEHRCYENGSCLEGTMTCGDIVQVRKKFKNL"
     gene            21924..22661
                     /gene="rlmB"
                     /locus_tag="PC366_002670"
     CDS             21924..22661
                     /gene="rlmB"
                     /locus_tag="PC366_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HDF2578170.1"
                     /translation="MASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLDKSK"
     gene            22664..23191
                     /locus_tag="PC366_002671"
     CDS             22664..23191
                     /locus_tag="PC366_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HDF2578171.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            23256..23903
                     /gene="sigH"
                     /locus_tag="PC366_002672"
     CDS             23256..23903
                     /gene="sigH"
                     /locus_tag="PC366_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HDF2578172.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            23977..>24368
                     /locus_tag="PC366_002673"
     CDS             23977..>24368
                     /locus_tag="PC366_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HDF2578173.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDG
                     AILVCSATDGPMPQTREHILLSRQVGVP"
BASE COUNT        10094 a         2524 c         4521 g         7229 t
ORIGIN      
        1 taaatgttat tactttataa aaaaataata agtacaaaaa aaacaatata tggcatataa
       61 gttgctatat aaataataag gagggaacaa ttataaatga ggcaaagaat aaaaaactta
      121 attgaaaatg aagataagaa aaatccttta acagatgaag cgatttcaag taggttaaat
      181 attcgaagag aagatgttac ctttttgaga aatgagttaa aaatagaaga ttcaagacaa
      241 agaagaaaag ttgttttaat taaagctata aaagatattt taaaagaaga aaaaactata
      301 aataaaaatg atataacaag aagattaaac agcattgggt ttacagtatc aagatttaca
      361 gtcatacaat acttaaaaga gattcaagat tctggtgacc taaaacttga taaagagagt
      421 gatgataaaa aagaagaaat aatcaataat agagaaaata aagatatagc atttgataaa
      481 ctcataggta gtagtggtag cttaagtaca attataaaac tagccaaagc agcaattctt
      541 tatccacctc atggtcttca tactattatt atggggccaa ctggtgttgg aaagagtgag
      601 ttagcagagt gtatgtataa atttgcagta gaatcatcca gattccctaa gaatgcacca
      661 tttatagttt ttaatgcagc agattattca gagaatccac agcttttgct atcacagtta
      721 tttggacacg ttaaaggtgc ttttacagga gctgatgaga acaaagaagg attagtatca
      781 aaggcagatg gaggaatatt gtttatagat gaaatacata gattacctca tgaaggtcaa
      841 gaaatactat ttcaactgat tgataaaggt atggtcagaa agttaggaga aacaagacta
      901 acacataaaa tagatgtaat gattatttca gcaacttctg agccaataga ttctcattta
      961 cttaatacat ttaaaagacg tatacctgta acaattgaaa taccagaatt agttgcaaga
     1021 ccattaaatg agaggtttga cattataaat aatttcttct taatagaagc tcaaagaatg
     1081 ggagcaaaca tacatataaa gtcagatgta ttaaaagctc ttatgcttta cgattgtata
     1141 ggtaatgtag gtcaacttag aagtgatatt caagtagctt gtgctagggg actattaaac
     1201 caacttacaa acaaactaaa agaagtaaat ataagcatat cagatgtacc tggatatgta
     1261 aaacaaggtc ttataaaaat cagaaattgt agaggtaaaa tagaaaatta tgtagatggg
     1321 gatttaatta tagattcaaa tcttcaaggt gagatagaaa agaaaaatga agatatatat
     1381 acttttccag atgaaatata caaacttact gaaagaagac atattgattt attggaacaa
     1441 ggtttagatt ttgatgttat aaatagaatc attggaggag aattagaaag ttgcattcaa
     1501 aaatacataa aacaagttaa aaaagtttct attagtaaca atcttccaga tataagtcca
     1561 attgttggaa aatatatcgt agagctaact tatgaagtaa tcaaaatagc atcacaatac
     1621 ctaagttcac tagaaccgaa tctacattta tgtttagcag ttcacctaaa agcagctttt
     1681 gagagattaa aagaaggaaa agtaatatca aatgctcatt tgaaagaaat aataggaaat
     1741 tatccactag aatattctgt agcagaaaag gtagctcaat atttaaagga aagatataat
     1801 ataaacttac caaaagaaga aataggtata atagcaatat attttaaaat gagtagtaga
     1861 agagatatgt ctgaacaaaa aaagataggt gtacttctta tggctcacgg aagagtagca
     1921 tcttctgtat gtgaggttac aaataaacta ttaggaatta atcacgcaag gtatttagat
     1981 atgccatttg agaagaagcc ggaagaaatg attgaagaag ctactacaat aataaaagat
     2041 attgatgaag gtagaggtgt gattatatta gtagatatgg gttcactttc atattttgga
     2101 gatattattt ctggaaagac tggaattaat ataaggacaa tatctagatt tgatacattg
     2161 ctttctatag aggttatacg aagagcagtt ttaccagatt taacaataga cgagatagtt
     2221 gatgaagtta aaggtataga gccacaagta aaagaaaagg ttagtaaatg taacaataca
     2281 aaagtagatt ttagaaaacc tataatttta acattatgta ttactggatt agggggagct
     2341 tgtaagataa aaaaaatcct agaggaaaat attaaaagta taactgaaaa ggttgatata
     2401 gaacctatag gtatgattga atatccaagt cttgatttag agataaaaca aataagcaat
     2461 gataaaaatg taatcgccat agttggaaca attgaccctc agatagcaaa tatccctttt
     2521 tttagtctag tagacataaa tgataaagca aagttaaatc aaataaataa cctaattgat
     2581 acaaatcaaa ttggtgaaac aaataaaaaa tatgaattat cagatttaat acataaagaa
     2641 gatatatttg tggatttaca ggttaaatca aaagaagaag ttctaaaata tatgagtaaa
     2701 aaacttagag agaaaggtta tgtgacaaaa aatttctata aaaaagtagt ggaaagagat
     2761 aacttatttc caactgaatt atcagatgaa atagcaatac ctcacacaga tggaatagat
     2821 gtaattaggc cagctataag tatagccatc ttaaagaagc ctattgtgtg gagtaaaagt
     2881 aaagtaaaaa taatactttt attagctgta gaccaaaagt gttttaatcc attaagcact
     2941 ctactctcat ttatagaaac agatgaattt aagaagataa aaaacattaa agatagagat
     3001 tttattaggg agatgatatt agatggagtc aatgaaaata attagtagca atttaatttt
     3061 taaaaatatt gaagtgtcta acaatgaaga tgcattaaag tttttgggac aacgtttgtt
     3121 tgacgaacag tatgtaaaag aaagctacat acaagctgtt gtagcaagag aaaaaaagta
     3181 tgctacagga ttaccaacag aaatatacgg agtggcaata ccacatacag atatagtaca
     3241 tgtaaatgag ccaggaatag caattggaat actgaataaa ccagtaaaat ttataatgat
     3301 gggtacagac gatactgaaa ttgatgtaaa agttgtattt atgttagcag tgaaagagcc
     3361 acaagaacaa ttgcaactat tagaaaaact tatgactata tttcaagata agaatatact
     3421 aaataatatt gttgacttaa gtgaagaaag tgtgagtgat ttattaaact ctaaattgaa
     3481 aaattaaaca tgtaaagtat attaaaaatg taaaattaaa catgcaaagt atgttaaaaa
     3541 atataaaaag attattaaag atttctaact atagatatct ttaaaataaa ataatttcaa
     3601 tgggggtgac taatgtgact aaaaagatat tagttgcatg tggaacagga gtatgtactt
     3661 caacaattgc tataaacaaa ttaaagaaag cacttcaaga cattggtaaa ttggatatgg
     3721 ttaatattac acaatgtaaa gtagtagaag ttgcatcaaa agcacctgat tatgatttaa
     3781 taatttgtac tacacaagta tctagtagta taaaaacacc agtgataaat ggattacctt
     3841 ttttaactgg tgtcggaatg gataaattaa tcaatgatgt attagaagag ttagaattat
     3901 aattaaaaaa attaaggaac atggtctcta aaatcataag ttttagagac ttaaaattaa
     3961 ataatggagg gtctttatat ggagatatta aatttcattg ttggtctagg tgcacaagta
     4021 atgatgccaa taataatatg tatttttggt ttgatattag gtacaaaact aggaaaatct
     4081 ttaagagctg gtttaactgt gggagttggg tttataggtc ttaacactat tatagctttg
     4141 ctaacagata atttaggtcc agctacacaa caaatggtta agaatttagg gctaagttta
     4201 tcaataatag atgtaggatg gccagcagca tcagctatag cttttgcatc aacagtaggg
     4261 gctttaatta ttccaatagg tcttgtggta aatatagtta tgctaattac taatactact
     4321 caaactgttg atgtagacat atgggattac tggcattttg cttttacagg agctttagtg
     4381 gcaggggcta ctcaaagtgt aatgtgggga gtatttgcag cagtagcaaa tatggtaatt
     4441 gtattggtaa tggcagattt aactgctcca ggtatagagg aatatttagg tatgccaggt
     4501 atatctcttc ctcatggatt tacacaggca tttgttccaa ttgctatagt agtaaataaa
     4561 ttattagacc taataccagg tataaataag attgagataa atgctgatac attgcagaaa
     4621 aaatttggat tatttggaga acctttaata atggggtctg taataggtgt aataattggt
     4681 attgctgcga aatatgatat aaaaggaata ttacaattag gtgtaactat gggagctgta
     4741 ttaatattaa ttccaaagat ggcagcatta ttaatggaag gattattacc agtatcagaa
     4801 gctgcacagg aatttattga gaagagattt aaaaacagag gcaagattta tataggctta
     4861 gattcagcag taggaatagg tcatcctgtt acattatcag ttgcactagt gttggttcct
     4921 ttgactatac ttatagcagc tatattgcca ggaaataaag ttttaccatt tgcagattta
     4981 gcagtaattc catttgcact tgtattaatc gtaccaatta caaagggaaa tgtgtttaga
     5041 acattaataa taggaataat tataattact tctggattat taatcgcaac taacttagct
     5101 ccattattta cccaaatggc tttaaatgct agctttaaaa tgcctgaagg agcaactatg
     5161 atttcaagta tttgtgatgg tgcgaatcca ttaagttggg tatttgtaaa agttatgaac
     5221 tataaagtta ttggaggagt agtttttgga gttatagctt taggaatggc tatttacaat
     5281 aggaatagaa taataaatga aaataaaaag ctatctatag aagaataagg ttaaaacaat
     5341 tttattaagg agtgtatagg ttatgaaaaa atataaatat gattctaaaa ggtacttact
     5401 cagtgttaca ataccaggat tttttatgat tttaatattg atttatgcac tgtttaataa
     5461 ctatataaat tttaatttga atatatatag tttgttaata attgtctgta cttatggtat
     5521 attcaatact tttatatcat caagtaatcc taaaaaaatt attattgaca gcaaatgtat
     5581 acattttacc tcatttatga ctacacataa gtatgaaatt aaagatatag aaaagataag
     5641 aataagagaa ttttataata aaaaaattta tctaaaaatt aatgatggag acctttttaa
     5701 aggtaggtat tggataagaa caaatatgtt taataatagt atagcattat atagttattt
     5761 cattgagttg gaagagtgct tatatccaga ttcactaaga tttagaaata aaaaatttga
     5821 gaataagaat atataaaaat aaaaaattga attgaagcct aacttaatct tttttgataa
     5881 gatataagtt tgaactttat actaaatttt tagaattttc aatcaagaca ataacataat
     5941 agctaagcaa ttagaacaca actaagatgt ataaggcatg tatatgatga atgggaggat
     6001 ttaattaatg ttattagaga aattaagaaa agaagtatta caagcatctt tagacctttt
     6061 aaactataat ttagtgacat taacaggagg gaatgtaagt gggagagatg aacaaactgg
     6121 ctatatagca atcaccccaa gtggaatgga ttatagaaat cttacaccaa gtgatattgt
     6181 tatagtagat gtagatggaa atattataga tggaaaatgg aaagcatcag tggatttatc
     6241 agaccacttg tatatatata agcatagaga agacataaat agtataattc atacacattc
     6301 tacatactca agttgttttg ctattttaaa tgaacctata gaatgcgcaa gtacaactct
     6361 tgcaaatgaa gtagggggtt cagtaccagt tgcaaaattt tcaccaccaa catttaaaaa
     6421 gatgggaaaa tgtgttattg aagcaattgg tgacaaaaga gcatgtcttt tagcaaatca
     6481 tggcgtaatt gcagttggtc catctgtagg acatgctctt acagccgctg taatgttaga
     6541 agattcagca aaagtatatt acttagcaaa atcaattggc acaccagtgc tactgcctga
     6601 tgaagaaatt caaagagcga gagatgtatt ttttaatgtc tatggtcagg ataaataaat
     6661 tagataaaat tttaaaagta atatgaaaat atagatattc aatgatatta aggagattta
     6721 taatgatata ataagtttaa tagttaagaa gtaaaatatg aaatgtaata gtatataaat
     6781 tcatttaaga ctaaaaataa taagataaaa taaaaaggag tctgtatttc tatgtattac
     6841 ttattaaaca aaagcacaaa tccttacttt aatttggcat tagaagaata tctattttta
     6901 aatgataaat ataatgatga tattataatc atatggagaa atgaagactc catttttata
     6961 ggtaaaaatc aaaatccata tcaggaagta catcatgatg ttattgaaaa gggagaaatt
     7021 cctattttaa gaagaatatc tggagggggc actgtttatc atgatttagg taatatcaat
     7081 atgtcattca tacaaaaaga taggcaactt catgagatag attttttgga gcatactaag
     7141 tttatgcaaa agatgctttc aaccttagga ctagatgtat ctataactga aagaaaagat
     7201 ttatttttaa atgggaaaaa aatttcaggc tctgcacagt ctataaaaag aaaaaattct
     7261 ctttatcatg gaactcttct ttacgattca gatttaaata aattaactaa atatttaaat
     7321 tcaaataaag caactgaatc aaatgcaact aaatctgttt caagtaaagt tacaaatatt
     7381 aagtttttac tcgaaaaaga tataaattac tttttagatt attgtgttga atatttaaaa
     7441 tctaatataa agaatataaa agaacttgaa ttggatgaag aagatattaa aagtgtatac
     7501 aatataggag aagataaata tagaaagata gagtggacat atggtaaaac gccgaaattt
     7561 caagtagtgc taccatttaa taatgaaagt aaaataaata tacatgttaa cagatggaaa
     7621 gtatcaaaat tttttatttc ttatgatgat aatgtaatta atatggataa gttgttagat
     7681 ttgaatttct ttaaagaaga aataaaagag agtattttag aaaattatcc acattacata
     7741 gatttaatca atttaatatt ttaatataaa acctctaatt tgataaaatt gtcttatatc
     7801 aaactagagg tttttaatat tcttgcatat taacaaccat tacaaaattg taaaattaaa
     7861 aacaacacta ttgaaaaatc aatatatatt gtaataaata tatgtgtttt tcattagcaa
     7921 atagacatta actatttata caactgaaaa tttaatatat aattaatcag atggttaaaa
     7981 taaaaatatt aaaagtttta ataaatgatg gttaaaaata aaatacgagg tgataccatg
     8041 tacagtgtta taattgttgc agcgggaagc ggaaggagaa tgaacttaga tataaacaaa
     8101 cagttcataa aattaagaga aaaagaaatt attgctcata caattcaagt tttttatgaa
     8161 aatataaata tagatgaaat agtggtatgt ataaaaaaag aagaagagga tttttttaaa
     8221 gaaaatataa taaataagta taactttaaa aatataaaaa tagcatatgg cggaaaagaa
     8281 agacaggact caatatataa tggtttaaaa aaattagatg aaaattgtga tatagtactt
     8341 atccatgatg gagcaagacc atttgtcgac catagaataa tcaacgaatc tataaaggta
     8401 gctaaagaaa aaaaggctgt ggttgtaggt gttccagtaa gtgatactat aaagatagtg
     8461 tcagatggaa cagtacaaga aactccagaa agaaatttgt tgtgggcagc acaaacccct
     8521 caaacctttg aatataatct cataatagat gcttatgagc aagcatataa gaacaattat
     8581 tatggtactg atgattcaat gttggtagaa aatataggtc aaagtgtcac tatggtaatg
     8641 ggttcttatg aaaacataaa aataactagt ccagaagatt taaatatagc agaacaaata
     8701 ttaaatatgg aaaaaagaga tgaagttaac agtagaagga gaattatatg agaataggat
     8761 taggatatga tgtacacaaa ttaacagaga atagaaaact tataatcggt ggtgtagaga
     8821 taccacacga taaaggtttg ttgggtcatt ctgatgctga tgtattgata catgcaataa
     8881 tggattctat tttaggtgct ctagcattag gagatattgg gaagcatttc ccagatacag
     8941 atgaagaata taagggagca gatagtatga aattattaga acatgtgtat aatctaataa
     9001 caagtaaagg atataaaatt ggtaatatag atagtactat aattgctcaa agccctaaga
     9061 tggctccata tattgagagt atgagaagta atatatcaaa agttttaaac acagacattg
     9121 ataatataaa cataaaggca acaacagaag aaggtcttgg ttttacagga gcaaaacagg
     9181 gaatagcttc acaaagtatt tgtttattat tgttgacaag tcagaataat taatatatta
     9241 ttagtaataa gtttaatgga tatcaagtaa taggcctata tagaatatct ataatgtatg
     9301 aatttaagtg aaattaatat aaatataaaa ttagctatga taaagaaata gtaaaatgat
     9361 gaaatcttca cagagagaaa acggtggtga gagttttcaa gaggaagtct ttgaacctgt
     9421 cttttagctt aaaggtataa aaatctttac ggtaggaacc gttatattcc caaaagagag
     9481 ctattcatat agctaactag agtggtaccg cggaaattaa acctttcgtc tctatacttg
     9541 tatagagatg agaggttttt tatattttca ggaagttaat attcaggagg aatctattaa
     9601 tgaaaatgtc aaaaatgttt atgccgacat taaaagaaat cccagcagat gctgagatta
     9661 caagccatca attaatggtt aggtcaggca tgataaaaaa aatgacttca ggtgtttata
     9721 accaattacc aatggggtta agagtgttca aaaaaattga acaaataatt agagaagaat
     9781 taaataaaaa agattgtcaa gaaatacttt gtgcagcctt acttccttct gaattatgga
     9841 aagagtctgg aaggtggact gctatgggtg aagaaatgtt tagactaaaa gacagaacag
     9901 aaagagagta ctgtcttggg ccaacacatg aagaagcatt cactgatata ataagacaag
     9961 aaattacttc atataaacaa ttgccactga acttgtacca aatacaagta aaatatagag
    10021 acgagagaag accaagattt ggtgttatga gaactaagac ttttacaatg aaggatgcat
    10081 atagttttga tgtagatgat aaaggtttag ataagtcata tcaagatatg tttgatgcat
    10141 atgtaagtat atttgataga tgtggattgg agaatagccc tgtacaggca gattcaggag
    10201 ctataggagg ttctacatca gccgaattta tggttaagtc agaagttggt gaagatgaag
    10261 ttgtattttg tagtggatgt gattatgcag ccaatgtaga aagagcagaa tcttgtaatc
    10321 tagcatcaca aaaagaagaa atgaaagaat tagaagaggt tcatacacca ggagcagcta
    10381 caataaaaga gttagaagaa tttttaaaaa cttctccaga taagtttgct aaaactttag
    10441 tatatgaggc agatggaaaa acagttgtag tcgttgtaag aggagataga gaagttaatg
    10501 aaatcaaagt atctaatgct ataggttctg ttatagaatt tgctcttgct acagatgatg
    10561 tagtgagaaa agtaactaat gcagaagtag gatttgcagg tccaataggt ataaatgctg
    10621 actatgtatt tatagataaa gaaattgttg aacaaagaaa catagttgtt ggggctaata
    10681 aaactgagta ccatataaaa aatgctaact atggaagaga ttttgaagga atagttggag
    10741 attttagaaa tgttcaagaa ggcgaccagt gtatagtatg tggtaagcca cttgaaatag
    10801 ctagaggtgt tgaagtagga catatattta aactaggaac taagtactca gaatctatga
    10861 atgcaaactt catagacaaa gatggaaaat caaagcctat agtaatggga tgttatggaa
    10921 taggtgttga aagaacagca gcagctataa ttgaacaaca taatgatgag aaaggtataa
    10981 tatggccttt gtcagtagct ccataccatg ttgtgatagt tccagcaaat atgaaaaatg
    11041 aagaacaaat atcaatagct gaaaatatat ataatgattt gcaagctatg ggtgtagaag
    11101 ttttattaga tgacagagat gaaagaatag gtgtcaaatt caatgattca gaattaatag
    11161 gaatacctat gaggattaca gtaggtaaaa atattaatga aggtaaagta gaatttaaac
    11221 ttagacataa agaagataaa gagataattg acatagaaga aataaatgaa aaagtaaagg
    11281 cagagtttat caggaataat gttaggttag gataataact taaataagat attgtataga
    11341 taatcaaagt tgtactttat agacaccatt ttatctatat ataaggatat aaaatggtgt
    11401 ttttttataa aacaaataaa tgaggaggta attgaaatgg caaaaaatga aaaacaattt
    11461 gttgaagaaa taacaaagat ggaagatgat tttccacaat ggtacacaga tgtaataact
    11521 aagactgact tagttgatta tgcaccagta aaaggtttta tggttgtaaa gccatatgga
    11581 tatgcattat gggaaaagat gcaagaattt atggataaaa aatttaaaga aactggacat
    11641 aaaaactgtt attttccatt attaatacca gagagtttat taaacaaaga agcagaacac
    11701 gttgaaggtt ttgctccaga agttgcatgg gtaacacatg gaggaaataa aaaattagaa
    11761 gaaagattat gtgtaagacc tacttcagag actataatat gtacaatgta tgcgaaatgg
    11821 ttaaaatcat atagagaatt accatatctt tataatcaat ggtgctcagt tgttagatgg
    11881 gaaaaatcaa ctagaccttt cttaagaaca tctgagtttt tatggcaaga aggtcataca
    11941 ttacatgaaa cagcagaaga agcacaagaa gaaacaatac aacaattaga agtatataaa
    12001 gcgttatgtg aagaattact tgcaatgcca gttgtagctg gtcaaaaaag tgaaagtgag
    12061 aaatttgcag gtggtgaaag aacatatact atagaagcta tgatgcatga tggtaaagca
    12121 ttacaatcag ggacaagtca cttcctaggt caacacttta ctaaggcttt tgatattact
    12181 tttgcagata gagaaggaaa tttagctaat ccataccata catcttgggg agcatctaca
    12241 agacttatag gtggacttat aatgactcat agtgataaca gaggtttagt attaccacca
    12301 agagtagctc caattcaagt tgttatagtt cctatagctg ctaaaaaagg aaatgtaatg
    12361 gagactgttg ataaaatata tgctgattta aaaactaagg gagtagccgt agaagttgat
    12421 gatagagata actatacaac tggatggaaa tttaatgagt gggaaatgaa aggtgctcca
    12481 gtaagagttg aaattggacc aaaagatata gaaaataatc aagctatggt atttagaaga
    12541 gatactttag aaaaggattc tatgccttta gaaggattag ctgatgctat atgtgattta
    12601 tttgatgtta tacacaatga tatgtttgaa aaagcaagaa aacatagaga agacaataca
    12661 tctatagttg aaaatatgga tgagtttaga aaagctttag aagaaaagcc aggattcata
    12721 aagactatgt ggtgtggaga tgcagaatgt gaagctaaga ttaaggaaga aacaggagca
    12781 actataagat gcttaccttt tgaacaagaa aacttaggtc acaagtgtgt gtactgtgga
    12841 aaagaagcag atagtatggt agtaatggca aaagcttact aaaatacatt taaataaaaa
    12901 ctggggtaga aagtatttaa tactttatcc cagttttttt gttttttatg agtaataaaa
    12961 tgtatttgta actatgtcat aagataagtc atagatactt atattaaaaa gaatataata
    13021 gagaactatt tttaataatt acatattaat gaaagcaaaa tatttttgtt atatagattt
    13081 tcaataaagc aaacaataaa tataaatgaa tattagtaag gagtgctttt aatttttaga
    13141 aaataaatga cttaaaagaa agatttatga aattaaaact aggattttct gatataataa
    13201 acatgtgtat ttttaaataa aaaggatatt attattagat ttgattaaaa ataaacttgc
    13261 aaaacaatgt actagtttaa tattatagtt atattgaata aaatatcagg aggaagtaaa
    13321 aatgaatgta agagtaaggt ttgcaccaag tccaacagga tttgtacata taggtagttt
    13381 gagaactgct ttatataact atttatttgc aaaaaaaatg ggtggagaat atatattaag
    13441 agtggaagat acagaccaaa gtagattagt agaaggtgct atagagaata tgcttaatgc
    13501 tatgaaatgg gctggtgtca accatagtga aggtgttata ttagatgata gtggaaaagt
    13561 agtacaaaaa ggagaatatg gtccatatat tcaatctcaa agattagata tataccaaga
    13621 atatataaag caacttttag atagtggaaa agcttattat tgtttctgta caaaagaaag
    13681 actggatgaa gtaagagatg ctcaaagagc agcaggagaa acagctaaat atgatggtca
    13741 ttgtaagaat ctttctaaag aagaagtaga agcgaatata aaagcaggaa taccatatgt
    13801 tataagatta agattgccag agaatcatac aattaagttt acagacttag ttagaggaga
    13861 tatggaattt aatactaatg acctagatga ccaagtatta atgaaaacag atggatttcc
    13921 aacttatcat tttgcagtag ttgttgatga ctatttgatg aaaattacac atgttataag
    13981 aggagaagaa tgggtatcat ctactccaaa acatgtttat ttatatgaag cttttggatg
    14041 ggaagcacct gtatttgtgc atttaccaaa tatacttaat aaagaaaaga aaaaattaag
    14101 taaaagacaa ggtgatgtag ctgttgaaga ctttaagaaa aaaggatatt taccagaggg
    14161 attagtaaac tatgtagcat tagttggttg gtctcctgaa gataatcaag aattgtttac
    14221 aatggaggaa ttagaaaaag ccttctctgt agaaagagta tctaaaagtg gtggagtatt
    14281 tgatactgaa aaattaaatt gggttaatca gcactatata aaagatggtg atgatgctta
    14341 tctaacagac ttagcaatac catttttagt agaagatgga tttataacag aagaagaagc
    14401 tactaataaa tatgatttct taaagagtat gatatcagta cttaaagaga aattacaata
    14461 tgtaaaagaa attactgaac atgcaagtat attttttgga gataaaatag aggtagaaac
    14521 tgaagaggga agagagttct taagattaga acatatacct actttaatag atgctttgag
    14581 agaaaaaata gaaaaaacag aggtattaaa tgctgagttt gttcaagcta tgcttaaaga
    14641 aatacaaaaa gagtacaaaa taaaagggaa aaatttattt atgggctcaa gaataatttt
    14701 gacagggcaa atgcatggtc cagatttacc aaaagtaatg gaagttttag gaaaagaaac
    14761 ttgcttaaat agaatagctt atgtaaaaaa taatatatta tagtcataaa agtccgctaa
    14821 tttagaagcg gacttttttt gtgttagtat ttggtgaaaa tatctgctta agaaaatgaa
    14881 ggtatttaag gtaataaatt taatatataa aaagcaaagc aaaaatataa ataaaatatg
    14941 aataataaac taataaaata ttaagcatag aagaagggaa tctattattt tagtttgatt
    15001 taattattaa gggggtaatt actatgtata gtaatattga tgatgttaaa aaggaattaa
    15061 aggagctatg cttagaatat gttacaattt tagaaaaatt aaaagatgaa aaaatgatta
    15121 cagaagaaac ttttgaaaag tgctcttctc aaaaaaaaat atttttagaa gaacaataga
    15181 ggatggtaat agtattatta ttatgtagtt tgaaagatag tacgaaaaat gatagtaata
    15241 ctattattta ttgcaatttt caactataat ataatatata atgttaagaa gataatttat
    15301 aaaaatacag tgaggtgatg agtgtgaaag tttataatac attgactaga acaaaagaag
    15361 aatttgttcc attagaagaa ggaaaggtaa aaatgtatgt gtgtggtcca acagtttata
    15421 actatataca cataggtaat gcaagaccat ttataatatt tgatactcta agaaggtatt
    15481 tagagtatag aggatacgat gtaacttatg tacaaaactt tacagatgtt gatgataaga
    15541 ttataaatag aagtcatgag gagggaatat ctcctgaaga agttgcggct aagtatataa
    15601 aagaatattt tgtagactgt gatgggctag ggataaaaag agctactgtt catcctcagg
    15661 ttacagataa tatacaacag attatagagt ttataaaaga gttggaagat aagggatatg
    15721 catatgcagt aaatggtgat gtatattttg atacaaataa atttgaaggt tatggaaaac
    15781 tttcaggtca aaaacaagaa gatttagagg caggggctag aattgaggtt aatgaccaaa
    15841 aaagacatcc tatggacttt gttctttgga aggcaaaaaa agaaggtgag ccaggatggg
    15901 atagcccttg gggagaaggt agaccaggat ggcatataga atgttctgtt atgtctaaga
    15961 gatatttagg tgaaacaatt gatatacatg caggtgggca agatttaaca ttcccacatc
    16021 atgaaaatga aatagctcaa agtgaagcta gaagtggaaa aatattctca aaatactgga
    16081 tgcataatgg atatataaat ataaatgatg aaaagatgag taaatcaaaa ggtaatttct
    16141 ttacagtaag agatatatca aaattatatg atttagagat agtaagattt ttcatgttat
    16201 cagcacatta tagaaatcca gtaaacttta gtgatgagat gttaaatcaa gctaaagcag
    16261 gtcttgaaag actatataat actaaagaaa aattagaatt tacgctaagt aatttagtag
    16321 aatctccttt aacagaaaaa gaagtagagc ttgttaaaga attagatgac tttagacaaa
    16381 aattcataga tgctatggat gatgatgtta atacagcaga cgcagtaagt gtaatatttg
    16441 aattagctaa gttaataaat tctaatgtag atgaaaattc ttctttggag tttgctaaaa
    16501 aatgcttaga tgaatttaat gaacttacag gagtattaaa tattgtaaat aagaaaaagg
    16561 atactgtatt agataaagac attgaagaat tgatacaaaa aagaactgat gcaaagaaaa
    16621 ataaagagtt tcaattagct gatgatatta gacaacaatt actagatatg ggaattgtat
    16681 tagaagacac aagacaaggt gttaagtgga aaaggatata aaaatggaaa aaactgaatt
    16741 agttactatg tcaccattag ttttagcata cttaggtgat acagtgtatg agacatatat
    16801 aagagaatat ttaattagac agaatacaca aagaaaagtt aatgatttgc ataaactagc
    16861 tataaagtat gtaaaagcta aagctcaggc aactataatt catgaaattg aaattgagtt
    16921 aactgaagaa gagagtaaaa tttataaaag gggaagaaat caaaagtcaa atacttctcc
    16981 taagaatgca gatattatag actacaaaca tgcaactggg tttgaggcat tagtgggata
    17041 tttgtattta aataatgaaa tagagagact tcaatatatt atcaataaag gaatcaaaat
    17101 tattgaaaga gatatgtaaa tattaaagag tgttgtctta ataataagta ataaggcaac
    17161 acttttttta taactaatgt ataataaata tatagaaatt agtaatgaga aaggataaga
    17221 aagttatgaa agtaaaatta atatcacata cacctgaacc agaaaaagta atagctatgg
    17281 cagctaagct atgttattca ccagttggga cagacgaaat agaaaaagat ttctaaaata
    17341 tattaaagag cattcctata acaaatacta tggcggttgg aatctatgag aagttataga
    17401 tatagaatta tgtaaattat ttggaaaaaa caggtttgaa aattagccat gttggtattt
    17461 ctaggttact taaggaagat caaacataaa taagctgagt tgtcttaggt gcactatgta
    17521 caacattaga atgtgaagtt gaagatttat tacttcaaac gaacgatggt actaagaaaa
    17581 acaatgatga aatgattaat taataataaa ggtaaggagg tagtatatga gtttagcaga
    17641 taaaattttt attgatatgt gtaataatat tcttgaaaat ggagtatcat cagatggaga
    17701 ggtagttaga gcaaaatggg atgatggcca gcctgctcat acaataaaga agttttgtgt
    17761 agtaaatagg tatgatcttt caaaagaatt cccaatactt acactaagac caacaaactt
    17821 aaaagcagca atagatgaat tactttggat atggcaaaaa aaatctaata atataaatga
    17881 tttgaatagc cgtatttggg atagctgggc tgatgaaaca ggttcaatag ggaaagctta
    17941 tggataccaa attggacaga aacataaata caaagaagga gaatttgacc aaatagatag
    18001 agtgatttat gacttgaaat ataatcctta tagtaggaga attataacta atatatataa
    18061 tcataatgat ttaaatgaaa tgaatttata tccttgtgca tatagtatga catttaatgt
    18121 aactggaaat agattgaatg caatattaaa tcaaagatca aatgatattt tggtagctaa
    18181 taattggaat gtaactcagt atgcaatttt agttcacatg ttagcacaaa taagtgattt
    18241 ggaagtaggc gaattggttc atgttatagc ggatgcacat atatatgata gacatattcc
    18301 tctagttaaa gagcttatta atagagaatc ttatgatgca ccaaaattaa taataaatcc
    18361 aaacataaag aatttctatg actttagagt tgaggacttt acattagaaa attataaaag
    18421 tgggccacaa atcaaaaaga ttcctgtggc aatttagaag gagttattta tgaaagttat
    18481 agtagctgta gatttaaatt ggggaattgg ttatggtgga aagttactac agtcgattcc
    18541 tgaagatatg aaatttttta aagaaaaaac tgtaggtaat gtagttgtaa tggggagaga
    18601 aacctttaaa tcattaccag gaaaaaaagc attaaaagat agagtgaata tagtcttgac
    18661 tagaagtaaa tcttttaatg atgatagatt gattgtttgt aattctatag atgaaactct
    18721 taaggaacta caaaaatatg aaaatgataa aatttttata ataggtggag aaacagtata
    18781 taaacaattt ttaccttatt gtaatgaact atatgtaaca aaaatacaga agacatatga
    18841 ggcggataga tttttcccta atatagatat tatgtcaaac tgggatttga ttaaagaaag
    18901 tgaagtaaaa gaatataaca atataagata tgttttttca acatatataa ataatagttt
    18961 ataggtttgt ataggagaga aatttaattt atgaaaaagg atatatttgt aaatagagtt
    19021 tctaatgctt tagaaaatga tagaggcgca gtttttgtag gtagtggtat atcgtttagt
    19081 tcgactgaag ttgattggtt taaattactg gagccattag taaatgaact tgatataaca
    19141 ttagacaata aaagtgatga tttacctatg attgctcagt acatagtaaa taattattca
    19201 ggaaatagag ggcctttagt aaacgaaata tcaaaaacat ttaatagaaa gtttaaacta
    19261 aacaagtatc ataagtattt agcaacaact aaactttcaa caatatggac aactaattat
    19321 gatatgttgt tagaagatgc attttatgat tttgatacat cggttaaagt aagtgatgat
    19381 tctattacaa ggaatagact agaatatgat gtggaaatta taaaaatgca tggatgtatt
    19441 tctagatccg attggaatga aatagttata actcaagaag attatgatga tttttcaata
    19501 aataaaccag ctatatctca aagattaagt gaagatttaa taaataagtc ttttctattt
    19561 attggatata gctatagaga tccaaatata agaaatataa tgataaatgc tagaaggcta
    19621 agtaaaaaac atactcaaca acattatata attttaaaaa agttaaaaga tagtgatagt
    19681 aatattacgc aagatgatgt agtaagacaa gaactttggt gcaatgattt aaaacgtttg
    19741 ggaatttcaa ctttatttat agatgaatac tcagagttag aggaactttt aagagagata
    19801 agtcaaaaat caagaggtaa aacagtatat gtgacaggtt ctcataaaga aagcaatatg
    19861 aatgcaagaa aattaggaac caagctagca aaacataaag atattacttt actaagtggt
    19921 caatcatctg gtattggctc agaggtagtt gctgcgttta ctgaagagtg tattaagagt
    19981 aaagaagata ttataaatag aatgaaaata tttcctaatc catattcagc tgatgaaaaa
    20041 tactctgatg atattacttt aataccagat ttaaagaaat gtagaactaa aatgttgaat
    20101 tcaacacaag ttgtagttgt atttagtgga ggtataggta ctgaagcaga gatagatgtt
    20161 gctataaaac aaaactgtaa tataattcct gttataacat gtaaagagga tagagagaat
    20221 ccagctataa aaaaaatctt aaactatagt gataatatga aaaatataga aataaaagat
    20281 gctacctatt ataataaaat agtagatgaa gatggtgttg taacaatgga ggaaatttat
    20341 atatgcatat caaaaataat gaattaaaac atgacattat taaattgaaa aaaagaaatg
    20401 gatttattga agttggaaaa gataaaaaaa cgttggtaaa ctgtttaatt ggagcgaatg
    20461 aattagagga ttacaaatat gaaataaaaa aaatagattg tatacttaat atatcagaaa
    20521 aaccagatat agtttcagat ttaagtacta aaagaagaaa aataagtgaa tctatatggt
    20581 ataagatagt taaagataca cctttcgtat ctgctacact gcccatatac ttagttagta
    20641 aaaataataa taaaatagat agtaatgaat tattagatat aattattgag cagatggaaa
    20701 atggagttgg gatgataacg attcatccaa cagcaaataa acaaattttt gaggattcta
    20761 agaatagaat ggtacctgtc acatctagag gtggaggtat ggtaatacaa gatttaatct
    20821 caaaaaattt ttcagaagat aatgtgtatt tgaaaatatt gccagaaatt ataaagtatg
    20881 ctcaaaaaca taatgtttgt atcagtctag gtgcaacatt tagatcagga aacatatttg
    20941 attctaatga tagagcacag ataacagaaa ttaagagtca aatagaatta gctaagagga
    21001 tatataaaag taatgtcggg gttattattg aatcaccagg tcattcaaga ccaagtgaca
    21061 taattaaaat atcgtcaata ttaaaaaaag aaggtttccc aattatgcca ctaggaccaa
    21121 taccaacaga tattgcaata ggaatggatc atatcgctgc agctattggt gctacaatta
    21181 tgggtataga aggatgtgca aatataatat caactgtcac acgagaagaa catactggag
    21241 ggagaccttc tattgaatcc acagttgaat ctataagaac agcaaaaata gctgctcata
    21301 ttattgatat acatcaaatg aatgatatta acttagatat gagtgtatct aagtctagag
    21361 ctaaatctaa cacctgtata tttgggaaag atacaagata ttgtgacaga tgtagagaac
    21421 tgtgtccttt gtgcattaga taaaaattat attcaagtta attcaataaa aaagattgga
    21481 taaaaataca tcgtatagct agtttttcac aacagagtca aagatatgtc aaattagagc
    21541 aatttgaata cataattcct ccagaaatag aaaaaataga aaaagcaaaa gagttattta
    21601 taaattcaat gaaaaaatac caagaggatt atgataaatt agtagagata ctatttgaaa
    21661 atcattataa caaactaata aaaggtggta aaaacgagaa aacatcaaaa agacaagttg
    21721 agaagaaagc aatagaagat gctagatacg tatttccaaa tgcgtgtgaa acaaagatgg
    21781 tatttactat aaatgctaga agtttgttta atttctttga acatagatgt tatgaaaatg
    21841 ggagttgtct agaaggaact atgacttgtg gagatatagt tcaagttaga aaaaaattta
    21901 agaacttgta ggaggtgaat aatttggcga gtatagaagg aagaaatccg gtaatagaag
    21961 caataaaaag tgacagagaa atagataaaa tattaattgc aaattcagct aaagaaggtt
    22021 caattaagaa aataatagga atggctaaag ataagaatat aattattcag tatgttgata
    22081 aacataagct agatgaagta agtacaagtc attcacatca aggtgtaata gcttatgcaa
    22141 gtgagtataa gtattatgaa ttagatgagc taatagattt agcaaagaat aaagatgaag
    22201 acccattttt cattatatta gatgagataa cagacccaca taatttgggt tcaataataa
    22261 ggacagcaga tgcagtagga gcacatggag ttatcattcc aaaaagaagg tctgtacaca
    22321 taactcctgt agttgccaaa gcatctgctg gagcagtaga atatatgcca gtttgcaagg
    22381 taaccaatat agttaataca ataaaaagac tcaaagaaga agggctgtgg attgctgcag
    22441 ctgatatgga tggagaaact ttttataaac aaaatcttac tggtcctctt ggtgtagtaa
    22501 ttggaagtga aggttttgga atatctagat tggttaaaca aaactgtgac tttatagtaa
    22561 aaatgccaat gataggtaat gttacatctt taaatgcatc tgtagcaggt ggaatacttt
    22621 tatatgagat attcagacaa agactggata aaagtaaata ggcatgaaaa aaaatataaa
    22681 tcattactta ataatagatg gctacaatat tataaatgcg tgggacaatt tgaaagaact
    22741 ggctaaagag gacttagaag attctcgaga aaagcttatt gatgacatta tagaattttc
    22801 tgagtttatg ggttataaga ctataatagt ttttgatgct tataatgtta aaaattctcg
    22861 agaaaaagtt gaaaaaagaa aacacataac aatagtttat acaagagaac accaaacagc
    22921 agatagttat atagagaaat ttataacttc tttatcaaag tatgatgatg taaaagtagc
    22981 cactaatgac tatgcagaac agcaaatgat tttaggaaaa ggtgctacta gaatgtctgc
    23041 aagagaatta aagttagagt tagatcgttc caagaataaa atgaaggaaa aaaatatcgg
    23101 tttgaggaaa aaaattcagc gaaattggtt ggaggaaagg ttagataaag aaacattgtc
    23161 gaaacttgag aacattcgta gaaagcgttg aaattactag gttctttaga ctataatata
    23221 cctataaatt tgttttatat atgggggaga tttacatgtt ggtagcaaaa gaaaaaagtt
    23281 atgagttagt ggacaattgt cagcaggatg agtataacat tgtattaaga gcaagtgaag
    23341 gggataaaat agcactagag tacattatta ctaaatacag aaattttgta aaggcaaaag
    23401 caaagtcata ttttttaatt ggagcagata aagaagatat aatacaagaa ggaatgatag
    23461 gcctttataa ggcagttaga gattttgatg gaagtaagac caattcattt aaatgttttg
    23521 cggagatatg tataacaaga caaataataa ctgctataaa aactgcaaca agacaaaaac
    23581 atataccttt aaattcatat gtttctttga ataaaccaat atatgatgaa gagtcagaca
    23641 gaacactttt agatattata gctacaagta tagtaacaga tccagaagag cttataatta
    23701 gtaaagaaga gttaaaaaat atagaatcaa aaatgaacga attgttaagt gacttggaat
    23761 tagaagtact agaattatat ttaaatggaa agtcatacca gtttatagcg gacaagctta
    23821 aaagagatgt aaagtcaata gataacgctt tacaaagggt taagagaaaa ttagaaaaac
    23881 atcttgaaaa cagaaatgat taatagtaaa atacttacca taagcttatt gtgagcaaaa
    23941 ttaatttata tcgaaagata agggaggaaa ttcaaaatgg ctaaagctaa atacgaaaga
    24001 acaaaacctc atgttaatat agggacaata ggacacgtag accacggtaa aactacatta
    24061 acagcagcaa taacaaaaac attatatgac agatatcaat taggagaagc agtagatttc
    24121 gcaaacatag ataaagctcc agaagaaaga gaaagaggaa tcacaatatc aacagcacac
    24181 gttgagtatg aaacaccaaa tagacactat gcacacgttg actgcccagg acatgctgac
    24241 tacgttaaga acatgataac aggagcagca caaatggacg gagcaatatt agtttgttca
    24301 gcaacagatg gaccaatgcc acaaacaaga gagcatatac tattatcaag acaagttgga
    24361 gtaccata
//
LOCUS       DAMJWO010000067        23217 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.068, whole genome shotgun sequence.
ACCESSION   DAMJWO010000067 DAMJWO010000000
VERSION     DAMJWO010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23217
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.068"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(190..558)
                     /locus_tag="PC366_002674"
     CDS             complement(190..558)
                     /locus_tag="PC366_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2578174.1"
                     /translation="MKKIPKSELLVMNFIWDKGIDKIPAREVANYMEISHGWTKGTTG
                     KVLSRLSDKGFLEFEKDGRNTLYTIKVKHEEYLKFETKDFLELIHKNSIHSFISSLGC
                     GNEISDDDIKELEQWLKKRK"
     gene            complement(1086..1508)
                     /locus_tag="PC366_002675"
     CDS             complement(1086..1508)
                     /locus_tag="PC366_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HDF2578175.1"
                     /translation="MNTFKTEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQ
                     KNNKRFKVEITNFEKNRVYEIKTSNKRESTITRYELVHIDLENTKLIFIESESKRNIF
                     GKINSALVRVLFGKRQPEEFNKFIKKLEMELENNSVNL"
     gene            1986..4889
                     /locus_tag="PC366_002676"
     CDS             1986..4889
                     /locus_tag="PC366_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2578176.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISAILQKNKNISISEITRELMTEGFNISRRVVEELLPKESLEM
                     DVVEESEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIIGESGVGKSLFS
                     RHMYEFAKQKKIVKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDTPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILVL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     IEYTEIRKYLKNAIFIPFNLEESSVKGSLLSDEYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSNEEIFSMSDLNSFVSDSLVKLVKELMNDIVEKNM
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     ISIKIPDDEIGFITLYIKSALKNEVKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNISTKTID
                     RVDLLMALEATRKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIVTLCLTGEG
                     TAKYISKTLEEKYDNTKCYQMSALDENLFCKIENLKETNNILAIVGTINPKIPGINFI
                     PYNKELFKNLDIYLSKSKQQDDRPVKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIFDKFKHL"
     gene            4922..5368
                     /locus_tag="PC366_002677"
     CDS             4922..5368
                     /locus_tag="PC366_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2578177.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKETYINAVLERE
                     RTLPTGLDIGEMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLDVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNIKLLKNIKNASTKEEVAKLLDFIEI"
     gene            5491..5793
                     /locus_tag="PC366_002678"
     CDS             5491..5793
                     /locus_tag="PC366_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2578178.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            5974..7380
                     /locus_tag="PC366_002679"
     CDS             5974..7380
                     /locus_tag="PC366_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDF2578179.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPIITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFSDPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRINTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVISMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGLSVVIYFVLWALFRKNKTSIL
                     DYLEKQALKNVEEEPVAV"
     gene            7724..8782
                     /locus_tag="PC366_002680"
     CDS             7724..8782
                     /locus_tag="PC366_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF2578180.1"
                     /translation="MGDKMRASVLYNVGDVRYEMVDIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVKHINVGDRVAVAPLVPCGKCDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEEHILKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIRVGDSVVVLGCGPIGQFVIQWAKVFGASKIIAVDIFDEKLELSKLLGANYILNS
                     KEVNVIKEIKKITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATECILRGELTLKGSWNSYASPYPGRAWTATLDFMGKGDIIFKPMISHKIGLNEVGDF
                     LSKMSKREINFNKILVEI"
     gene            8857..9543
                     /gene="araD"
                     /locus_tag="PC366_002681"
     CDS             8857..9543
                     /gene="araD"
                     /locus_tag="PC366_002681"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDF2578181.1"
                     /translation="MLEILKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNVVDGKLRPSSDTPTHLVLYKEFEELGGIVHTHSSWATI
                     WAQIGKSIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNIMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            9561..10208
                     /locus_tag="PC366_002682"
     CDS             9561..10208
                     /locus_tag="PC366_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HDF2578182.1"
                     /translation="MLDSLKGKVVEIAIKAEHYGLCKEKTGNFSIRDKDTGYILITPS
                     GIGREELNVEHICVLDLNGNVIEVEKGIKPSSEVLMHIEIYKIRENINAISHTHSLYA
                     TAFSVAKKPIIPIVYESVNYGGYVDIAPYERPGTLKLAKSVSKLLIDTDACLLERHGL
                     TTVGNDLDEALLKSRYVEEVAEIYYRSLVLNQFKELEVVDVDEFESWKYPEEIKF"
     gene            complement(10381..11748)
                     /locus_tag="PC366_002683"
     CDS             complement(10381..11748)
                     /locus_tag="PC366_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HDF2578183.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLRSISNVATKIVPFMAV
                     IYVVICGIILISFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTVSLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(11938..12026)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            12454..14574
                     /locus_tag="PC366_002684"
     CDS             12454..14574
                     /locus_tag="PC366_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDF2578184.1"
                     /translation="MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKPIKRLWISSSTDKAIKDGFAKLRSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESILKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSKICNKLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNVLEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKEIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRIFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQNKNQETFNNPFAEALAKLKNK"
     gene            14678..15931
                     /locus_tag="PC366_002685"
     CDS             14678..15931
                     /locus_tag="PC366_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HDF2578185.1"
                     /translation="MDLSGIFKYYCKECENTWNNSSVELFEDIETYSKDSQKKREKEL
                     DKFINTISVHLERYPSDAVLRKMWVKKGEVFLQKTLEKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDDDLPIGDIMQAMRNVWISNALQLLFGKEIYYSKANFAYSMLYPYTD
                     NYLDNTNIDKNDKILFNNWLEKRLLGEHIKSKDYHESKVSQMIDYIESVYPREKFTQV
                     YESLLLIFKSQVNSLKQHGKENHLCKEDLLSISIEKGGSSVLVDGYLISGFMTKEEIE
                     FCIGYGFLLQISDDLQDIKEDLKYNHKTIITEMSKEGTLDKVVNKLINFTIELIDSFK
                     INNKNKSVITMIKNDCLMLILFSVVYNAEFFSVGYIKEVEKFIPYTIDYSLEIEEKIK
                     EKFKNIDVLNNENEYKEMIDIICAE"
     gene            complement(16085..17146)
                     /gene="ytvI"
                     /locus_tag="PC366_002686"
     CDS             complement(16085..17146)
                     /gene="ytvI"
                     /locus_tag="PC366_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HDF2578186.1"
                     /translation="MDIQKQKNFIIKFTYVVLITSIVYIVLKFLLPLLMPFVISFIIA
                     SILRPIIRLITNNTNLNRTLISIVILLIFYGLCIFLLVSFGVKIFASVSDVFFRLPEI
                     YKSSIQPTLNTLFSKIDASTPNVNLSLILGWDNISQSMMSLVASISTNALNAIASIAS
                     KTPAFMLKLIITLIASFFFTFDYQKIVNFILKQFPEKSQFMIINIKNSSINALLKLLK
                     AYAILLSVTFLELLIGLTILKVENAFTISVIIALVDILPVLGTGSILTPWMIISLING
                     NINLAIGLLILYIIITVVRQILEPKVVGHQIGLYPLITLMCMFIGAQLFGIAGLFGFP
                     IAATIIKNLHDNGIITAFK"
     gene            17420..18160
                     /locus_tag="PC366_002687"
     CDS             17420..18160
                     /locus_tag="PC366_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HDF2578187.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILKELN
                     IKYIFDYRSDEEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSYYNLPINNPSYKKLVELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVS
                     RENIMKDYLKSNDFADKEIERFIEYKPKFKDIPKENLKYIFGVNEEYMKTAFRRIDEE
                     YISVEAYLYGEFNLNKEEIRKLRNQYLE"
     gene            18172..19950
                     /locus_tag="PC366_002688"
     CDS             18172..19950
                     /locus_tag="PC366_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2578188.1"
                     /translation="MSLNITARQINIIKILLNSKDTISGIALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEGSFDEVNLNSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRILEKYSISVKSKHKQGICVLESEDKILNCIVD
                     LSNKRDNQLSLNDFLNDDIKERKLLIKKLLLDILNENGLVLTDIEFKSVLNNILVMLS
                     RHKYNEKEFIENYIENYRSKRSSILENEQNKEIIINSIKTFCKNLKLATSIDISNDKV
                     FEEFLYKHISSLCKKIKLGINQSPIMAQDIKIKYPFAFELANIAKKTIEKDLKIEINE
                     DEVANIALHIGGAVERASYNNKDKVFKTIIVCTSGIGTSMLIKAKLENIFKEKLEILK
                     IIPSYLVEYIKVIDVDFVISTVPIEVGDVPVINISPILSEKEIRLIEKYIETGNIYLD
                     LDIKSLFDSELFFTDLVFKRKEEVIDFMASKLVQKGYIDEDMKKSYFEREKIATTEIG
                     NMVTIPHGAIGKIFDNKIAIGILKKPISWEISDVRLIIMLALDKDKILDYEVIFSKIY
                     KRVDSIAKVISICENSSFEKFVNLFN"
     gene            20117..21034
                     /gene="pfkB"
                     /locus_tag="PC366_002689"
     CDS             20117..21034
                     /gene="pfkB"
                     /locus_tag="PC366_002689"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDF2578189.1"
                     /translation="MIYTVTLNPSIDYIVKLDELKTGSTNRVKEEYVYPGGKGINVSR
                     ILKELGNDNTSLGFISGFTGEYIIRTLEEKELKTDFIKIKSGFSRINVKIKALKETEI
                     NGQGPNIDDEDIDTLYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMVKYAKRLKEMGAINVLVS
                     MGKDGALLITEEDEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKQF"
     gene            21071..22990
                     /locus_tag="PC366_002690"
     CDS             21071..22990
                     /locus_tag="PC366_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2578190.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAILAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSSSEKEFKEIIDKKEREKFSEEYQD
                     EKVAEKNIIDTKENDANKYPKVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YTINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIVLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
BASE COUNT         9245 a         2519 c         3929 g         7524 t
ORIGIN      
        1 atttaatata tttaaattta ttttagatat aaacatcatt ctgactacta ttaaaagaca
       61 tataaaataa ttaaacttaa aagtatattt gcttatcttt ttagtaaata aaatgaaaaa
      121 aagaattagt agacttatgt aaatattaaa tttaataact tctataaata attccataaa
      181 atacgtctcc tattttcttt tttttagcca ttgttcaagt tcttttatgt catcatctga
      241 tatttcattt ccacaaccta atgatgatat aaagctatga atagaatttt tatgtataag
      301 ctctaaaaaa tcctttgttt caaattttag atattcctca tgtttaactt taatagtgta
      361 taaagtattt ctaccatctt tttcaaattc taaaaaacct ttatcactta atctagaaag
      421 tactttacca gtagtacctt ttgtccatcc atgagaaatt tccatataat tagctacttc
      481 tctggctggt attttatcta tgcctttatc ccatatgaaa ttcataacta acaactcgga
      541 ttttggtatt tttttcaata taatcactca cctttaactt gattatatta gacaaatgtc
      601 taatagtcaa tataatatat catcatgtat aaagaatctt tatattattt tatgcttgag
      661 aactaagtag tatagattta tagataaaaa agatattgag agttttatgg aagaggggaa
      721 tatattttct attagagata agaatatgac atatattttt tattgatttg tacaaaaata
      781 ctatatagtg aataaattaa tatcttttct aaattagaag aggataatct tattagataa
      841 agattatcct ctttattgaa agtttaaggg atattagaga ttattaattt ttctctcttt
      901 ttttaactaa aagcaataat acataaaatt attattgcta atgatactct taatgtggta
      961 tatagtcata gtgtcacatg tttatcaata gttttttcat taattattgt aacgaatagt
     1021 aggactcata aaatacttag aaatatgttt ttagatagat tttaaatata taatctaact
     1081 tatatctata aattaacact attattctcc aattccattt ctagtttttt tataaattta
     1141 ttaaattctt ctggttgcct ttttccaaac aatactctta caagagctga attgattttt
     1201 ccaaatatat tcctcttgct ctcactttca ataaaaataa gttttgtatt ttctaagtca
     1261 atatgtacta attcatatct agtaatagta ctttctcttt tattgcttgt ttttatctca
     1321 tatactctat ttttttcgaa attagttatt tcaaccttaa atcttttatt atttttttgt
     1381 tgtacaaatg ttcctactgc ttttttctca ttaaaattag gaaaatttag tcttgcagat
     1441 tttgtaaata tattaaatat gtcttttgca gaatatttta ataaaacttc agttttaaat
     1501 gtattcatat cgttttccct tctgtatata aatttaatat ttataagtta atttttaagt
     1561 taaaatagta taatatgcca tattaaatca tgttaaaact atttatatag ctaaaacctt
     1621 acctatataa gtatgtatac tatcatataa aaataaaatc ttaaaataga aagggttaaa
     1681 aacacagttt attataattt ttattgttga gtagatacgt actattatat atgattgagc
     1741 aagtttttca atcataaatt tataaagtat tttgcattaa aatttaaaca aagagttaaa
     1801 ttatttaaga ttatgaataa ctaatacatt tagtaaatta ctaaatatac aaaatgtaaa
     1861 tacttatcaa aatgtataaa tacttatgac atctagttac ttacagggtt taagtagaaa
     1921 aaaatatcaa agtaagtatg gcatgatagt tgcttatata tttatcaaga aaggagttat
     1981 taagcatgga gttgagagat aaacttgtaa acatcataaa tacagaaaat aaaaaagatc
     2041 cattaacaga tgttcaaata gcaaagtttt taagtacaac tagagagaac ataactaatt
     2101 tgagaaaaga acttaatata agtaattcaa ggcaaagaag atatccttat ttaaaatcag
     2161 caatttcggc aatattacaa aagaataaga atatttctat atcagaaatt acaagggaat
     2221 tgatgacaga aggctttaat atatcgagaa gagttgtgga ggaactttta cctaaagaaa
     2281 gtttagaaat ggatgtagta gaggaatctg aagaagaatc gaatgaccca tttgaaactc
     2341 tgataggtaa taaagggagt cttagaaatg ctgtggagca ggctaaatct gctatattgt
     2401 atccaccaaa aggattacca acgttgatta ttggggaaag tggagttggt aagagtttat
     2461 tttctagaca tatgtatgag tttgcaaagc aaaaaaagat agtaaaagaa agctccaatt
     2521 ttgttgtatt taactgtgct gattatagtg acaatccaca attattatta tctttgttat
     2581 ttggatataa aaaaggtgca tttacaggtg ctgaatatga tacaccaggt cttgtagaag
     2641 aagctgatga aggagtttta tttttggatg aaatacatag attgcctcca aaaggtcaag
     2701 aaatactatt ttctatctta gataggggaa agtttaggag attaggtgaa actaatgctg
     2761 aaagaaaagt aagtattatg ttgattgggg caactactga aaatgtagag actaatttat
     2821 tattaacatt cagaagaagg ataccaatgc taataacttt gccaccatta catgatagat
     2881 tactaaaaga gaaaatagac cttatataca atatctttca acaagagtgt aatagaataa
     2941 atgcaaaaat atttgtagat aaaaatgtga ttgaaatact tgtactaaaa aagtttagtg
     3001 gaaatatagg acaattacaa aatatgattc aggttctttg tgcaagagct tttatgaagt
     3061 ttataaattc caaagatgaa gatagtgaat cgatagtagt agtagatata aatgaagttt
     3121 taaagcttaa agattctttt aaagatgctg cctttcaaga gattgaatat acagagataa
     3181 gaaaatattt gaaaaatgct atatttatac catttaattt agaagaatca tcagtaaaag
     3241 gaagtctttt aagtgatgaa tatatattac cagaggacat atacaaaaca attgaaaaga
     3301 aatattatga cctaaaatcc ctagacattg aagatataga tatagagaat attttatgga
     3361 cttttatttt aaatagattt gctgacttaa agtttaatct cgatagtaat gaagaaattt
     3421 tttcaatgag tgatttaaat agttttgtaa gtgatagttt agttaaactg gtaaaagaac
     3481 ttatgaatga tatagttgaa aaaaatatga atttagaagt aaataaaaat atgttcaaat
     3541 atctagcaat acacttagaa gaagctataa aaagaattaa gctaaatcaa aagataataa
     3601 atgtaaattt agaaaaaata aagattgact tttcaaaaga atatgaaatt agtaaaagtt
     3661 ttgcaataaa aattgaggaa tcaattagta ttaagattcc agatgatgaa attggattta
     3721 taacactcta cataaagtct gctctaaaaa atgaagtgaa aaaagataaa gtagggttaa
     3781 taataatttc tcatggacgt atagctacag agactgtaaa tgtagttaaa gaacttttag
     3841 gtgtaaagtt tcctgtggct atagatatgc ctttagatga aaaaccaata aatatataca
     3901 ataaggcagt agaactgtca aaaataatag accaagggaa aggtatattg tttttggtgg
     3961 atattggttc acttacaaac ataggtcaaa tagtaaataa gagaaccaat ataagcacta
     4021 aaactattga tagagtagac ctcctaatgg cactagaagc aactagaaaa gtttctatgg
     4081 gagaggaaga acttgatgaa atattttttt ctttgctaaa agataggatg ggatataact
     4141 atgaattaga aaaacacata gataaatcaa atgcaattgt aacattatgt cttactggag
     4201 aaggaactgc taagtatata agtaaaacgt tggaagaaaa gtatgataac actaaatgtt
     4261 atcaaatgag tgcattggat gaaaatttat tttgtaaaat tgaaaatcta aaagagacaa
     4321 acaatatatt agctattgtt gggacaataa accctaagat accaggtata aattttatac
     4381 cctataataa agaacttttc aaaaatttgg atatctatct atcaaaatca aaacaacaag
     4441 atgacagacc agttaaatcg tatgaaagaa tgcttgatga ggatttagtg atttttgaac
     4501 cagatatata ttttaaaaag gatttattag aatatgtatg ttcaattctt ataaataaag
     4561 aatatgtaga aaaagattac ttagattctg ttttacatag agaagaaatg cttccaacat
     4621 attctaaagg agctataggt gtgcctcatg gagattcttc tactgtaaat agtacaaggt
     4681 ttgtttttgt taaactaaag aatcctattg attggggtgt aggtaatgta aatttcatat
     4741 ttatgccagt ttttcaggct aatgataaag agattgttaa aaatgttctt gagatactaa
     4801 aagatgcaga atttatgaac aatgccaata agtgttttga taaagatgct tttagaagga
     4861 ttatatttga taaatttaaa catctgtagc catagcaaaa aaattgagag gagttagagt
     4921 aatgaatgta gatttaatat cattgggttt agaatctaat gattatgaaa gtgttattga
     4981 agaattagga agtataatgt gtaaaaaaga atatgtaaaa gaaacataca taaatgctgt
     5041 cttggaaaga gaaaggacat taccaacagg tctagatatt ggagaaatgt gtgttgctat
     5101 tccacataca gattcaaagc atgtaaatga gtctaatgta gctgtaggga tattgaaaaa
     5161 tcctgtaaag tttaattcaa tgatagaccc aaaagataga cttgatgtag aacttgtatt
     5221 tttattagca gtaaagaacc cagattcaca agtaaaactg ttaaaagatt taatgtcagt
     5281 ttttcaaaat ataaagttat taaaaaatat aaaaaacgca tcaacaaaag aagaagtagc
     5341 taaattattg gattttatag aaatttaatg taggagaatt ttataaataa aaaattaaaa
     5401 tttcaacaat caaagtaagt attatttttt taataggttt aatcttatat aaaataaaaa
     5461 tttagagtga aaaattagga ggaaattatt atgaaacaat ttaatgtatt atcagtttgt
     5521 ggttcaggga cagttacatc atctatggta gcaggtaaat taaaagaagt actaggtaat
     5581 aaggggattt ctattactac aacagaagct agaccaacag aagcactaaa tttagcacaa
     5641 tcaggaagat ttgactttat aacatttacg agtccgcttc aaacaggcga ttatggaata
     5701 ccaactataa atgcatttgc ttgcctaact ggtatagggg aagaggcatt ctttgaagaa
     5761 gttttgactg ttattgaagg catagataag taagttttgg agacgtgaat ttatagtatt
     5821 taaatcaatg atttagatac tataataagc taatattaac taaatatttg tggaaaaaac
     5881 attttatatg ttgtcataaa ttaaaaaatt ataaaaatag tcacttaagt attaaattaa
     5941 gcttataaat atttataagt aggagggaaa aagatgttag aatttatgaa atctataatc
     6001 gatacatttg gttctgcaat tatagttcca attataatat tcataatagc aaagatattt
     6061 aaagtaacta ctaagaaatc gtttctttct gctgtgtatg caggagttgc tttacaaggt
     6121 tttacactga ttttaaattc atttacacca ataataacac cagttatcaa taggatggtt
     6181 gagagtacag gagtaaacct accagttttt gatgttggtt ggcaagcaac atcattggtt
     6241 gcattttcaa caagtgcagg tatgatatat ttaggtcttg gtatattatt acaaacaatt
     6301 ttatttttga taaaatggac agacgtgttt caaccatcag atttatggaa taactattct
     6361 tatatggtat ggggagcaat ggttatagga gtaacaggaa attttccttt aggtatagca
     6421 tgtatggttt tattaaactt atatagttta ttaatatcag agttagttgc aaagagatgg
     6481 tctagttact atagatatcc taattgtaca ataatagcta tgcataatgt tgaggcttct
     6541 gtgtttgcag tattttcaga ccctatatac aataaattgg gattaaataa aataaaatta
     6601 aatccaaaag aattagagaa gaaattaggg tttttaggtg aaccaattac tttaggtctt
     6661 tttttaggta tgtttatagg tatattaggt aatatgacga gaataaatac tatggaagct
     6721 tggggagaaa taatgaaagt aggtatatct acaagtgcag tgatggcgat tttccctaaa
     6781 gtagcaagta tgtttgctca agcatttgca cctataacag aagcagctag aaagattatg
     6841 caaaaagctg gaaaccgtga gtggtacata gcagtaaatg atgctgttgg atatggtgaa
     6901 cctgcaactt taatatcagg tcttatatta attccaataa tgcttgtaat atctatggta
     6961 cttcctggta ataaggtatt accagttgtg gatttgttgg caattccata tatggttcaa
     7021 ggtttagttg ccatacataa tggtaatata ccaaaagtat tagtttcagg tataatttgg
     7081 tttggattag gattatatgt ttgtacatct acagcaccat tatttacaga tatggctaca
     7141 aatataggtg tagctatacc tgcaggagca atgttaataa caagctttaa tatactagga
     7201 aaacctttga tgggattagt tttctttgca tttctaagtg caaatccaat ttatataggt
     7261 ctttcagttg taatttactt tgttctatgg gcattgttta gaaagaacaa aacaagtatt
     7321 cttgattatt tagaaaaaca agcacttaaa aatgtagaag aagagcctgt agcagtttaa
     7381 gtttataaaa atgaaataag aataattaaa ggagtttata attgatttta tataagtatc
     7441 agataatacc tgagaaatat ttaaatgaaa tatagacttc tttttatttg ataatatttg
     7501 taattataat gcattgtatt tttatagttg agttttctgt ataacctgct atttaaaaca
     7561 tactctttta tatttataca gtaatgtggt ttaattttat aaaatgtaat ctctactggt
     7621 aaaagacttt gtatataagg catttgcctg aataaaccat ttatcttttg tatggcatag
     7681 atattgctat atagaagtat atagcatgaa aggagatatt tatatgggag ataaaatgag
     7741 agcatcagta ttgtataatg taggtgatgt caggtatgaa atggtagata taccagaaat
     7801 aacagatacg caagtgcttg taaatgtaaa atatgttggg atatgtggtt cagatttgcc
     7861 taggtctatg gtaagtggtt tgagtggaaa tacaaaatat ccattgattt taggacatga
     7921 attttctggt gaagttgtta aaattggaga aaaagtaaag catattaatg taggagatag
     7981 agtagctgtt gcaccattag taccttgtgg aaaatgtgat tattgtaatg aaggtaattt
     8041 tggcttgtgt gatgattaca atataattgg aacaagagta aatggagcgt ttgcagaata
     8101 tgtaagagtt ccagaagaac atattttaaa actaccagat acattggatt atgaaactgc
     8161 tgccggaatt gaaccagcaa ctatagctta tcatgggatt tcaaagtcta atattagagt
     8221 aggagatagt gtagttgtgt taggatgtgg tccaataggt cagtttgtta tacaatgggc
     8281 aaaggtgttt ggtgcatcta agattatagc agttgatatt tttgatgaaa aattagaact
     8341 ttctaaactt ctaggagcaa actatatact taactcaaaa gaagtaaatg taatcaaaga
     8401 aataaaaaaa ataacaaatg gtggtgctga tgttgtaata gagactgctg gtagccgatt
     8461 tacacaagaa caatctctat ttgtagcaaa aaagagagga aatatagtgt ttgtaggtat
     8521 atcacacaca gaattaccac ttagtgcaga cgctactgag tgtatattac gtggagaact
     8581 taccttgaaa ggttcttgga attcatatgc aagcccttat cctggaagag catggactgc
     8641 aacattggat tttatgggaa aaggtgacat tatttttaaa cccatgattt cacataaaat
     8701 aggtcttaat gaagtgggtg actttttaag taaaatgagc aagagagaaa ttaatttcaa
     8761 taaaatccta gtagaaatat aaaaatttaa taaaaaattc taaaaacaat taaattttat
     8821 aactatgaca ttaaataaaa tataggagga agaaaagtgc tagaaatttt aaaagaagaa
     8881 gtattaaaag caaacttaga attacctaag aaaaagctaa ttacttatac ttggggaaat
     8941 gtaagtggga tagatagaga aaaaggatta gtggtgataa aaccaagtgg tgtagagtat
     9001 agtaatatga ctgtagaaga tatggttgta gttgatttag agggaaatgt agttgatggc
     9061 aaactaagac cctcctcaga tactccgact catctagttt tatataaaga gtttgaagaa
     9121 ttggggggaa tagtacatac acattcaagt tgggcaacaa tttgggctca aataggaaaa
     9181 tctataccat cttgtggtac tactcatgca gattattttt atggaagcat accatgtacc
     9241 agaaaaatga ctagagaaga aatttgcaat gaatacgaaa aggaaactgg aaatgtaatc
     9301 attgaagaat ttatgggaag aaatccaatt cattgtccag gaataattgt aaatgaccac
     9361 ggacctttta catggggaaa agatgcaaat gaggctgtac acaatgcagt agttttagaa
     9421 gaagtcgcaa agatggctta ttatacagag ttaatgagtc ctgataatat tatggataag
     9481 gttcttatga ataagcattt ttcaagaaaa catggaaaaa atgcatacta tggtcaaaaa
     9541 tgattatctg gaggtgaatt atgctagact ctttaaaagg taaagttgtg gaaatagcaa
     9601 ttaaagcaga gcattatggt ttatgtaaag aaaagactgg taattttagt attagagata
     9661 aggatactgg atatatactt ataaccccat caggtatagg aagagaagaa ttaaacgttg
     9721 aacatatttg tgtattggat ttgaatggaa atgtaataga agttgagaaa ggtattaagc
     9781 caagtagtga ggtattgatg catattgaaa tatataaaat aagggaaaat ataaatgcta
     9841 tatcacatac tcattcttta tatgcaacag cattttcagt agcaaagaaa ccaattatac
     9901 caattgtata tgaatcagtt aattatggcg gttatgtaga tattgctcca tacgaaagac
     9961 caggaacttt aaaattagct aagagcgttt caaaattact gatagataca gatgcatgct
    10021 tattagaaag acatgggttg acaactgtag gtaatgattt agacgaagca ttattaaaat
    10081 caagatatgt tgaagaggta gcagaaatat actataggtc tttagtatta aatcaattta
    10141 aagaacttga agtagtagat gttgatgagt ttgaatcttg gaaataccca gaagaaataa
    10201 agttttaatc taaataattt tcattgaagt ggttaattaa aatatatgta ttatttatat
    10261 caattactat gttttattat attaatcacc gtattttgta aatatattta ttacattttt
    10321 tcaaaaaaat atagaatccg aaagccatat aaaattgact tgggattcta tactttttat
    10381 ttatgcattt ttctttatct gattttctgg agaatttata tgttcaaaat attttttagt
    10441 ttcagatact attataggtg ataatgcaag taaagctata aggttaggta ttgccataag
    10501 cccatttaca atatcagcaa ttatccaaac aacttctaac tttaagaaag cacctaataa
    10561 caccatagcc acaaatacag ttctataccc attcatgcct tttacaccaa acagaaattc
    10621 aaaacatctt tctccataat aactccatcc caaaattgta gtaaatgcaa ataatgttaa
    10681 actaactgta agtaatattg gtccaaatgt aggaattgct ccgttaaaag ctgcttgtgt
    10741 cataacagct ccatttaggt ctgaacacca cactcctgaa ataacaagag agaatccagt
    10801 aagagtacag attataatag tatctataaa agtacctgtc atagatataa gaccttgttc
    10861 cgctggccat tcagttttag cagcagctgc agctattgga gcactaccta gaccagactc
    10921 atttgaaaat acaccacgag caataccatt tctaattgcc agtgacatag ttgctcctaa
    10981 aaaaccacca gtagcagcag taggtgtaaa tgcactttta attattaaca taaaagtttc
    11041 agggatttta ttccaaaaag atattaaaat gattccacag attacaacat atataactgc
    11101 cataaaaggt actattttag tagctacatt agatatactt ctaagtcctc caaatacaac
    11161 caaagctaca aatactgcta atacaacccc tgtaattcta gggtctatcc cgaaactatt
    11221 atttattgca tctgttattg aatttacttg agtaaaagta ccgattccta aaagtgcaac
    11281 tagtatacca cttatagcga aaaatattgc aagaggtctc catttttctc ccataccatt
    11341 tactatgtaa tacattggcc caccagacac ttgaccattt ttatctttag ttctgtattt
    11401 tattgcaaga acaccttctg aatacttagt agccattcca aagaatgctg ctatccacat
    11461 ccaaaaaagt gcaccaggtc caccagcttt gatagctgta gcaacaccaa caatattacc
    11521 agtaccaact gtagcagcta gagcagtaca taaggctgca aaacttgaaa catcaccact
    11581 acctttgttt tcagcagaga atattaactt aagagctctt ggcagtttag ttatttgaac
    11641 aactccaagc ttaacagtaa gtagtatacc agtaccaact aatagtacca gtaggggtgg
    11701 tccccaaata aaagcatcaa ctttgtttaa aatatcaatt agattcataa aaacactccc
    11761 tcattttttt tgctttacat aatcaataga atttttaatg aagtaattga caggaaataa
    11821 gtataattta ttaataattt ctagtgtaat aaaaaaagct aaatctaaaa aagattcagc
    11881 tctggatgta cactaattag caaccaaaat aaaagtatta gtaaatactg tttttggtag
    11941 ataatccctg tccttttgcc tgagagattg agcataaaag ccttgcccct tcggcgccca
    12001 taatgggtct ctccagagtt ccgtaaattt tacagtccta cttttaaaag tacctgagag
    12061 tgttactcct tcggtgtgct atatagcaac tcttctataa aatcttaacc ggatattgat
    12121 ttgtcatagc ttattgtatt aataatatta atataagttt ttatgttttg tcaactaaaa
    12181 aattaaaaaa caaagaaaaa atataaaaat gtaagcctat ttacgaatta taaacttaga
    12241 aagatgagta atatacgtaa aaatgaattt tgtaatacac atacaaatga agtgtaaaat
    12301 aagttttaaa taaaaaaata ataaaatctt aaataattaa ttagatatga ttaaattatg
    12361 gtaatattat agttacgata ttaagaaaag ttctatttag ttagatttta agcgtaatat
    12421 gagattatgt atagagaaag gatgtatttt tagatgggaa aaatattagt gctagcagaa
    12481 aaaccttctg ttggaagaga tatagcaaaa gttttagggt caaaaaatga aaaaaatggt
    12541 tatatagagg ggccaaagta tgtgataact tgggcactag gtcatttggt tacacttgct
    12601 gaccccgaaa gttatggaga aagatataaa tcatggagct tagaagacct gccaatactt
    12661 cccaagcacc ttaagactgt tgtaataaaa aagagtggaa agcagtttaa tacagttaaa
    12721 tcgcaaatga atagaaatga tatagatgaa atagttatag caacagatgc aggtcgtgaa
    12781 ggagaacttg tagcaaggtg gataatagaa aaatcacagg taaaaaaacc tataaaacgt
    12841 ctttggattt cttcaagtac agacaaagca ataaaagacg gatttgcaaa attaagaagt
    12901 ggaaaagaat atgaaaattt gtattactca gcaatagcac gagcagaagc tgattggatt
    12961 attggaataa atgcaaccag agctttgaca acaaagtaca atgcacagct ttcttgtgga
    13021 agagtacaaa ctcctactct tgcaatgttg cttaaaagag aagaagaaat aagaaatttc
    13081 aaacctaaag agtattatgg attagaatta attgctacaa agggaaattc agatataaaa
    13141 tttatttgga atgataaaaa caataattct tcaactttta gtaaagaaaa gatagaatcc
    13201 atattaaaaa aagtaaaagg tgtagacata aaaatatctg aagtaaacaa gtcatataag
    13261 aaaaaatatt cacctgcact ctatgattta acagaattac aaagagatgc aaataaaatg
    13321 tttggatttt cagcaaaaga aactttatct ataatgcaaa aactgtatga acatcataaa
    13381 gtacttactt atcctagaac tgattctaga tatttaacat cagatattgt tggaacatta
    13441 aaagatagaa taaaagctgt aaatattagt gattattcaa agatttgtaa taaattatta
    13501 aaaagcaata ttatagctaa taaatcgttt gttgacaatt caaaggtaac agaccaccat
    13561 gcaataatac caacagaaca gaaggtattc atgagtgatt ttagtgacaa agagcgaaaa
    13621 atatataatc ttgtagtaaa aagattttta gcagtactat ctcctccttt tgaatatgag
    13681 cagacaacta taagtgcaac tgtagaagga gaaatattta aggctaaggg aaacaaagta
    13741 ataaatttag gttggaaaga aagttataaa gatattgaag atgaagatga gtatgaaagt
    13801 ataccaaatg ttttagaaaa agatgtactt aaggtcaagg gattaaagat aacttcagga
    13861 aaaacaaatc caccaccata cttaaatgag ggaacattat tgactgctat ggaaaagaat
    13921 ggtctaggga cagttgctac aagagcagat ataatagaaa aattattcaa ttcattttta
    13981 atggaaaaga aaaataaaga gatatatata acatcaaaag gaagacaatt attagattta
    14041 gttccagtag acttaaagac accagaactt acagcttcat gggaaaagaa attattggat
    14101 atttcaaagg gaaaacttag taaaaataca ttcataaatg acatgaaaga ttattcaaaa
    14161 gatattgtac tagaagtaaa aaatagtgat aataaattta aacatgataa cttaactaaa
    14221 aatagatgtc cagaatgtgg taaatttatg ttagaggtaa atggtaaaaa aggtaagatg
    14281 ttgatttgtg aagatagaga gtgtaatact agaaaaacta tatcacaagt aaccaattca
    14341 agatgtccta actgtcataa aaaattagaa cttcgtggag aaggtgaggg gagaatcttc
    14401 acttgtagtt gcggatacag agaaaagttg tcttctttca acaagagaaa gcaagaagaa
    14461 aaacagaagg catcaaaaaa agatgttaat caatatttaa aaaatcaaaa taaaaatcaa
    14521 gagacattta ataatccatt tgcagaagca ttagctaagc taaaaaacaa ataattttaa
    14581 agttattatt atacacaatt ataactttaa ctgtatatta gttatatgta ctgatataat
    14641 atagtgtata gtttaggcat gaaagtaggg ctgttaaatg gatttaagtg gcatatttaa
    14701 atactattgt aaagagtgtg aaaatacatg gaataattcg agtgttgaat tatttgagga
    14761 tatagaaacg tatagtaaag attcacaaaa aaagagggaa aaagaattag ataaatttat
    14821 aaatacaata tcagttcatt tagagaggta tccaagtgat gctgtattga gaaaaatgtg
    14881 ggtaaaaaag ggcgaggttt tcttacaaaa gacattggaa aaagaaaata tttttaagtt
    14941 agaaaaaatg gatgtagagg atagaaaaaa atttttagat ataacaaaac agtttattag
    15001 agatgctaga aaatttgatg atgatttacc tataggtgat attatgcaag ctatgaggaa
    15061 tgtatggatt tcaaatgcat tacaattatt atttggtaaa gaaatatatt attcaaaagc
    15121 taactttgca tatagtatgt tatatccata tactgataat tatttagaca atacaaatat
    15181 agataaaaat gataagattt tatttaataa ctggttagaa aaaaggctcc tgggagaaca
    15241 tattaaatct aaggattatc atgaaagtaa agtatctcaa atgatagatt atattgaaag
    15301 tgtataccct agagaaaagt ttacacaagt ttatgaatcg ttattattaa tatttaaaag
    15361 tcaagtaaat agtttaaaac aacatggtaa ggaaaatcat ttgtgtaaag aagatttatt
    15421 atccatttct attgaaaaag gaggttcatc cgttttagta gatggatatt taataagtgg
    15481 atttatgaca aaggaagaaa tagagttttg tataggatat ggatttttat tacaaatatc
    15541 tgatgattta caagatataa aagaagattt aaaatacaac cataaaacta ttattacaga
    15601 gatgtcaaaa gagggtactt tagataaagt tgtaaataaa ctaataaatt ttactattga
    15661 gttaatagat agttttaaaa ttaataataa aaataaatct gtaataacta tgataaagaa
    15721 tgattgctta atgttaattt tattttctgt agtttataat gctgaatttt tttctgtagg
    15781 atatataaaa gaagtagaga aatttattcc atatacaata gattattcat tagagattga
    15841 agaaaaaata aaagaaaaat ttaaaaatat agatgtttta aataatgaaa atgaatataa
    15901 agaaatgatt gatattattt gtgcagagta gaaaaaaagg gagtgtctta gaatagactt
    15961 tttagtttat gaggcactct ttttgtataa aatcaaatgt attttcatca ttttaacaat
    16021 taaaaagagc ttatccctgt ttgagaaagc cctttttaat ttaaataaaa atgtcaaggt
    16081 taaactattt aaatgcagta ataatcccat tatcatgtaa gttttttatg attgtagctg
    16141 cgatagggaa tccaaataat ccagctattc caaatagttg agctccaata aacatacaca
    16201 ttaatgttat taaaggatat aggccaattt ggtgtcctac tacctttggt tctaatattt
    16261 gtctaacaac ggttataatt atgtatagta ttaaaagtcc tattgctaaa ttaatatttc
    16321 cattaatgag tgagataatc atccaaggtg tcaaaatact tcctgtaccc aagactggca
    16381 aaatatcaac aagtgctatg atgacagata tagtaaatgc attttcaacc tttaggatag
    16441 taagtccaat aagtagttct aagaatgtca ctgatagtag tattgcatag gcttttagta
    16501 gttttaaaag agcattaata ctgctatttt ttatatttat tatcataaat tgactttttt
    16561 ctggaaattg ttttaagata aagtttacta ttttttgata gtcaaaagta aagaaaaaag
    16621 aagcaattaa agtaataata agttttaaca taaatgcagg tgttttactt gcaatactag
    16681 caatagcatt gagtgcattt gttgaaatag aagctactaa agacatcata gattgactta
    16741 tattatccca accaagtatt aatgataggt taacattagg tgtactagca tctatctttg
    16801 aaaataaagt atttagcgtt ggttgtatac ttgatttata tatttcagga agtctaaaaa
    16861 atacatcact tacacttgca aatatcttca caccaaagct aactaataaa aatatacaca
    16921 acccataaaa aattaaaagt attactatag aaataagtgt acgatttaaa tttgtattat
    16981 ttgtaataag tcttataata ggtcttaaga tggatgcaat gataaaactg attacaaaag
    17041 gcattaataa tggcaataag aattttaata caatatatac aatacttgtt attaaaacta
    17101 catatgtaaa tttaattata aaattctttt gcttttgaat atccataata taaaacctcc
    17161 aatgtatttg atattattct aaatatggtc ttttttacag aaaatatact actgtatatt
    17221 gattataaac tataaagctt atgtaaagta aataaattat gtaaaattta ggttaatttt
    17281 gtataaagag atacttttat attttacaat taataaccaa atactaaaaa atattttaaa
    17341 taaagaactt aaaattgtga taaaattaat ttatagatat taaaaaaagt ataatatatg
    17401 gtttttaaga ggtgctaaga tgaaaaattt tagagattta ggtgggaaca aaactgagga
    17461 tggcagaact gtaaagaagg gattatttta taggtctgca aaattatcaa atctaagtga
    17521 aaatgatata aagattttaa aagagttaaa tattaaatat atatttgatt atagaagtga
    17581 tgaagaagct cgtaaacatc catcaacaat aatatcaaat ataaaaaata taagaatacc
    17641 agcaatgaga gagctagaag aatcaggagg aagttttggt tctattgaag atatgattga
    17701 tggattgttt gaaaaagatg gtgcatttaa tatgttaaat aatagttact ataatttgcc
    17761 tataaataat ccgtcatata aaaaattagt agaacttata agagactatt ctaatttacc
    17821 aatattaaat cattgtacag ctggtaagga tagaactggt gtggggagtg ctataattct
    17881 tatgatttta ggggtatcga gagagaatat aatgaaagat tatctaaaaa gtaatgattt
    17941 tgcagataaa gagatagaaa gatttataga atataagcct aaatttaagg acattccaaa
    18001 agaaaattta aaatatatat ttggtgtaaa tgaagagtat atgaaaactg catttagaag
    18061 aattgatgaa gaatacatta gtgtagaagc atatttatat ggagaattta atttaaataa
    18121 agaagaaata agaaaattaa gaaatcaata tctagagtaa aaggtgagtt tatgagttta
    18181 aatataacag caagacagat aaatataata aaaatattgt taaattcaaa agatacaatt
    18241 agtggtattg ccttaagtca agagatagga tgttcttcaa aaactataca aaatgaaata
    18301 aaggatatta ataaacaact tagaaatggt aaaattttgt caataagagg agttggttat
    18361 aaactagaag gaagttttga tgaggtaaat ctaaatagca atctctatga tgatgtagat
    18421 agagtagaat atataatcag aaaaatatta accttaagta atgaagaaaa aaatactata
    18481 aaacttgaag atttagccga ttctatgtat gtaagtgttt caacagtaaa aaatgattta
    18541 aaagaagtaa aaagaatatt ggaaaagtat tcaatatcag ttaaatctaa gcataaacaa
    18601 ggtatatgtg ttttggaaag tgaagataag atattaaatt gtatagttga cttaagcaat
    18661 aagagagata atcaattgag tttaaatgat tttttaaatg acgatataaa ggaaagaaaa
    18721 ctattaataa aaaaattatt attagacata ttaaatgaaa atggattagt attaactgat
    18781 atagaattta agagtgtgtt aaataatata ttagttatgt taagcagaca taagtataat
    18841 gaaaaagaat ttatagagaa ttatatagaa aattatagga gcaaaagaag ctcaatttta
    18901 gaaaatgaac aaaacaaaga aattataata aattcaataa aaacattttg taaaaattta
    18961 aaattagcta catcaataga tataagtaat gataaggtat ttgaagagtt tttatataag
    19021 catattagta gtttatgtaa aaaaataaag ttaggtataa atcaatcacc tataatggct
    19081 caagatataa aaataaaata tccatttgct tttgaactag ctaatatagc taaaaagaca
    19141 atagaaaaag atttgaagat agaaattaat gaagatgaag ttgcaaacat agctctacat
    19201 ataggaggag cagttgaaag agcatcttat aataataaag ataaggtttt caaaactata
    19261 atagtttgta cttcaggcat aggcacatca atgttaataa aagctaaatt agagaatata
    19321 tttaaggaaa aattagaaat actaaagatt attccttcat acttagttga atatataaaa
    19381 gttatagatg ttgattttgt aatatctact gttcctattg aagtaggaga tgtgccagta
    19441 ataaatatat ctccaatttt aagtgagaaa gaaattagat taattgaaaa atatatagaa
    19501 acaggaaata tatacctaga tttagatata aaaagcctgt ttgatagtga attatttttt
    19561 actgatttgg tgtttaaaag gaaagaagaa gttatagatt ttatggcaag taaacttgta
    19621 caaaagggct atatagatga ggatatgaaa aaatcttact ttgagagaga aaaaatagca
    19681 acaacagaaa tagggaatat ggtaactata ccacatggag ctattggaaa aatttttgat
    19741 aataaaatag caattggtat attaaagaag cctatttctt gggaaatatc agatgttcgt
    19801 ttaataataa tgttagccct tgataaagat aaaatattag attatgaagt aatattttca
    19861 aaaatatata aaagagtaga ttctatagca aaagttataa gtatatgtga aaatagtagt
    19921 tttgaaaaat ttgtaaattt atttaattag atgggtagta ttgtatatac acctgtaaat
    19981 ttggataata taaaactaaa taagataaaa acgataaatt tctcttttaa ttaagagaaa
    20041 ttttttgact ttcaaggata ttaatataaa gttaagatat aaacataaag caaataaata
    20101 aaaaagaggt ggcaatatga tttatacagt gacattaaat ccatcaatag attatatagt
    20161 taagctagat gagctaaaga caggaagtac aaatcgtgta aaagaagaat acgtttatcc
    20221 aggaggaaaa ggtataaatg tatctcgcat acttaaggaa cttggaaatg ataatacatc
    20281 tttaggtttt ataagtggtt ttactggaga atatataata agaacattgg aagaaaaaga
    20341 attgaagaca gattttataa agataaaaag tggtttttca agaataaatg taaaaataaa
    20401 ggcgttaaag gaaactgaga ttaatggaca aggtccaaat atagatgatg aagacattga
    20461 tactttatat aaaaaacttg ataagctaaa tcaagatgat attttaatat tggcaggaag
    20521 tataccatct actttagatg aaaaactata cgaaaatata atggctagat tagaaaaaaa
    20581 gaatataaaa gttgtagtag atgcaactaa aaatcttctt cttaatgttt taaaatacaa
    20641 accttttcta attaagccta ataacgacga attagaagaa ctatttggtg ttaaattaaa
    20701 ttcaattgaa gacatggtaa aatatgctaa aagattaaag gaaatgggag ctataaatgt
    20761 cttggtatca atgggaaaag atggagcatt gttgattaca gaggaagatg aagtgcttat
    20821 aagtgatgtc cctaaaggaa aagtaaaaaa ttctgtagga gcaggtgatt caatggtagc
    20881 aggatttata tctgggtatt tgaatactgg gaaatatgat tatgctctta aattgggagc
    20941 agcttcaggt agtgcaactg ctttttcata tgacttagcc aaaagagaat acattgataa
    21001 attggtaaat gagatatctg taaagcagtt ttaaaatatt aaaaaatata tagaaaggta
    21061 attaatattt atgaaaatta tagatttatt agatgaaaag tcaattaagt taaatttaaa
    21121 ttcaaaaacc aaatcagaag caatagaaga attagtagat ttggtcgcaa atagtggaaa
    21181 tttaaatgat aaagaaaact acaaaaaagc aattttggct cgtgaagaaa tgagtacaac
    21241 aggaattgga gaaggtgtag ctatacctca tgctaaaaat tcttcagtta ctaaagcttg
    21301 tatagcagca gcagtgtcaa aagaaggtat agattatgaa tcgtttgacg gaagtttatc
    21361 aaatctattt tttatgatag ctgcaccaga cggagctaac aatactcatc ttgaagtatt
    21421 atcaagatta tctacaatac ttatggatga agactttaga aataaactta taaattcaag
    21481 ctctgaaaaa gaatttaagg aaataataga taaaaaggaa agagaaaaat tcagtgaaga
    21541 atatcaagat gagaaagtgg ctgaaaaaaa tataatagat actaaagaga atgatgctaa
    21601 taagtatcct aaggttttag cagtaacagc atgtccaact ggaatagcac atacatttat
    21661 ggcagctgaa agtttaaata aaatggcaga aaacaaaggt gtatcaataa aagtagaaac
    21721 taatggttca gcaggtgtta aaaataagct tacaaaagat gaaatagaaa atgcaacatg
    21781 tataatagtg gcagcagata aaaatgttga gatggctaga tttaatggca aaaaagtcat
    21841 aaaaactaag gtggctgatg gtatacacaa agcggaagaa cttatagaca aggctgtaaa
    21901 tggagatgct ccaatttacc atggaggaga tggaagtcac aacgaatcaa atgaagaaag
    21961 tgaaagtgga tttagaaaag tatacaaaca cttaatgaat ggtgtatcta atatgttacc
    22021 atttgttatt ggtggaggga tacttatagc gatagccttt ttacttgatg attatactat
    22081 taacccttca aactttggtt caaatacacc gatagcagcg ttttttaaag ggataggaga
    22141 taaagctttt ggatttatgt tacctgtact tgctggatat atagcatact ctatatctga
    22201 tagaccagcg tttgttgtag gatttgtagg aggtgctcta gcaggtgatg gtggttcagg
    22261 atttttaggt gcactacttg caggttttat agcaggttat ttagtagaag ggcttaagaa
    22321 aatatttagt gtactaccag cttcattgga aggaataaaa ccagtattgt tatacccttt
    22381 acttggaaca cttttgatgg gaattataat gacattttta gtaatacctc cagttacagc
    22441 aattaataat gcaatggttg gatttttaaa tggtttaggc ggaacttcaa aaatagtttt
    22501 aggattagta ttaggtggaa tgatggctgt ggatatgggt ggacctgtaa ataaagcagc
    22561 atatgtattt ggagttgcat cacttgaatc agggcagttt gaaataatgg cagcagtaat
    22621 ggctggtggt atggttccgc cacttgctat agctcttgca actacatttt ttaagaatag
    22681 atttactaaa gaggaaagag attctggtaa agttaattat gtaatgggat tatcatttgt
    22741 tactgaagga gctatacctt ttgcagctgg agacccactt catgttatac cagcttgtgt
    22801 tggaggttca gcagtggcag gagcacttag tatgttgttc aacgcagctc ttcgtgcacc
    22861 tcatggagga gtatttgtta taccagtggt tacccatcca tttgcatata tattagctat
    22921 agctgtaggt gctttggttg gaatgatgct tttagcatta cttaaaaaac cattaaatca
    22981 agaagtatag caattaaagg atattcaaga acttaaaata tgatgtttta taaaaattaa
    23041 tatattgctg aattatttta aaataaggat tttattaaaa taaggatttt attaaaataa
    23101 ggattttatt aaaataagga ttttatgagg ctgttatata acgatttgta attgttatct
    23161 tgacagtctt ttatttttat ataagtaaaa taagtgtgtt ttgctttatt tgtattt
//
LOCUS       DAMJWO010000068        22974 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.069, whole genome shotgun sequence.
ACCESSION   DAMJWO010000068 DAMJWO010000000
VERSION     DAMJWO010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22974
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.069"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(763..1080)
                     /locus_tag="PC366_002691"
     CDS             complement(763..1080)
                     /locus_tag="PC366_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578191.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLEVLYRYVTGLEYISIGLFTRRLDITIIAIILVATITVILYYLVRKRY
                     ITI"
     gene            complement(1372..1941)
                     /locus_tag="PC366_002692"
     CDS             complement(1372..1941)
                     /locus_tag="PC366_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578192.1"
                     /translation="MKLRNPKIKKLLSVALLAALIGIPIGQTANAMEISNNVPSYIEN
                     NPTTIEDLEINDSQLPKPGTVTYIDINKLIKNLKENGIDTTLIENELYYRKAGTNKIV
                     WTKTGFDLYLSKGVALTLAGAGTGVAGLLAGAIPGIGQYLAAAIVGAITMHLGSNITS
                     GKIFKFKKMRYNKGGAYVTKYYLQSVRNQ"
     gene            2385..2775
                     /locus_tag="PC366_002693"
                     /pseudo
     CDS             2385..2775
                     /locus_tag="PC366_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902377.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            3095..3604
                     /gene="vanZ1"
                     /locus_tag="PC366_002694"
     CDS             3095..3604
                     /gene="vanZ1"
                     /locus_tag="PC366_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ1"
                     /protein_id="HDF2578193.1"
                     /translation="MKSRKHNITKGLFIVYIIILTWIILFKLQFDISSLETMNLRSIN
                     LVPFAGSLIINNRVDISEIILNVAIFVPFGIYVCMLKEEWSFIKKVIPIFITSLAFET
                     LQYIFALGASDITDLIGNTLGGIIGIAVFMLLSKIFKNNTIKIINVLALIVTIIVVLF
                     LGLVIFANL"
     gene            complement(3706..3900)
                     /locus_tag="PC366_002695"
     CDS             complement(3706..3900)
                     /locus_tag="PC366_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HDF2578194.1"
                     /translation="MSVIVMCSRCGKEIDKYRNKYITYYEKNTNAEIKVCINCALDLL
                     EKTRENQELNIREFQDTIIL"
     gene            complement(4415..4807)
                     /locus_tag="PC366_002696"
     CDS             complement(4415..4807)
                     /locus_tag="PC366_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2578195.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEINTTLYM"
     gene            5375..5737
                     /locus_tag="PC366_002697"
     CDS             5375..5737
                     /locus_tag="PC366_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578196.1"
                     /translation="MKIRKSGFISIECIISIAILYVAVYLVSTSLYNCYSFISRNISD
                     REMLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSRIEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            5721..6437
                     /locus_tag="PC366_002698"
     CDS             5721..6437
                     /locus_tag="PC366_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578197.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFELGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDVSNNEDEFREYFLGNNMIECIKKIKDTSYSS
                     LEELSLKVENNTIYDRGDFFEFDIESNVREKEFLKAIKVRVKIKNPWIGIDIEDYMDK
                     SNNNKIDDKTFNNYKASENNEILNQFKNESENIRNQEVVEFTEEDEEYEEELKQNIIE
                     NIKKNFDEKKLVQVYKYRGV"
     gene            6457..6876
                     /locus_tag="PC366_002699"
     CDS             6457..6876
                     /locus_tag="PC366_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578198.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNLENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKHEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDG
                     SPQKASTIEIYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            6866..7390
                     /locus_tag="PC366_002700"
     CDS             6866..7390
                     /locus_tag="PC366_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578199.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIMNVSNYEETFKKTTSIKCRYVDENNNEESISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVLITNNGQYVNIKLKLSKRSQKYE
                     TDFKIKVWNFSESI"
     gene            7702..8259
                     /gene="efp"
                     /locus_tag="PC366_002701"
     CDS             7702..8259
                     /gene="efp"
                     /locus_tag="PC366_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HDF2578200.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            8351..8806
                     /locus_tag="PC366_002702"
     CDS             8351..8806
                     /locus_tag="PC366_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2578201.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFADAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCPSCDDRE"
     gene            8969..9679
                     /locus_tag="PC366_002703"
     CDS             8969..9679
                     /locus_tag="PC366_002703"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HDF2578202.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGI
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINDDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            9733..10803
                     /locus_tag="PC366_002704"
     CDS             9733..10803
                     /locus_tag="PC366_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDF2578203.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPADTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYNPFTLEESVN
                     IVKKVLVLFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     ILQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKFGVLLKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            10831..14385
                     /gene="smc"
                     /locus_tag="PC366_002705"
     CDS             10831..14385
                     /gene="smc"
                     /locus_tag="PC366_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HDF2578204.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDVYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKILEVNSFIREIEGIEKELSEVNEHRKVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEINDIKEKLNE
                     NKQYIKELESNKLSGSEELSTLQENIKVLEASKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNIRDENINSEITELNKNIEIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSINLQDSISEHNKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKSAINYL
                     KQNNLGRVTFLPLNIIKSNKVSLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KISNIKNEISHLELKRESLDKDVKNIKNEIDSHESKIKDLEKSIIIKSTSIKNVESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKSDDVRKDMEELDDLYNKNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEAYNSIVRDIKRISGENCELEEKNKQLEESLNYEE
                     HEIIKLQDSIATEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRSLGNINIGSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAQEITDII"
     gene            14412..15692
                     /gene="ftsY"
                     /locus_tag="PC366_002706"
     CDS             14412..15692
                     /gene="ftsY"
                     /locus_tag="PC366_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HDF2578205.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDSLENLEETIFSG
                     LEEEVIDKVEDIEEKTEESVNNEGTEEIENFEKIEVEMDSNAKEVENISNNDSQEEII
                     EELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
                     EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTL
                     DIEPAPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWAN
                     RTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKI
                     VDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVK
                     SEVDVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            15795..16163
                     /locus_tag="PC366_002707"
     CDS             15795..16163
                     /locus_tag="PC366_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HDF2578206.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNRD
                     CANLIPKLENIEDVCREMIK"
     gene            16160..17512
                     /gene="ffh"
                     /locus_tag="PC366_002708"
     CDS             16160..17512
                     /gene="ffh"
                     /locus_tag="PC366_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HDF2578207.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEVDVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPVNIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMAELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIAKGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            17550..17822
                     /gene="rpsP"
                     /locus_tag="PC366_002709"
     CDS             17550..17822
                     /gene="rpsP"
                     /locus_tag="PC366_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HDF2578208.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            17887..18114
                     /locus_tag="PC366_002710"
     CDS             17887..18114
                     /locus_tag="PC366_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HDF2578209.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            18222..18737
                     /gene="rimM"
                     /locus_tag="PC366_002711"
     CDS             18222..18737
                     /gene="rimM"
                     /locus_tag="PC366_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HDF2578210.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLAVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVSREDSRELEEGEFFIA
                     DMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            18746..19441
                     /gene="trmD"
                     /locus_tag="PC366_002712"
     CDS             18746..19441
                     /gene="trmD"
                     /locus_tag="PC366_002712"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HDF2578211.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVYIYNIRDFSNN
                     KHKKVDDYPFGGGVGMVMTPQPIYDTYKHIITTHNISNPSVIYLTPKGKVYNQSIAKQ
                     MSLKEDIILLCGHYEGVDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            19626..19976
                     /gene="rplS"
                     /locus_tag="PC366_002713"
     CDS             19626..19976
                     /gene="rplS"
                     /locus_tag="PC366_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HDF2578212.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            20297..21193
                     /gene="ylqF"
                     /locus_tag="PC366_002714"
     CDS             20297..21193
                     /gene="ylqF"
                     /locus_tag="PC366_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HDF2578213.1"
                     /translation="MSNEYEEYLMDDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADRDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINNIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETL
                     ALRLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIAATV
                     LNEFRDGKIGNITLEVPENVKR"
     gene            21582..22874
                     /gene="brnQ"
                     /locus_tag="PC366_002715"
     CDS             21582..22874
                     /gene="brnQ"
                     /locus_tag="PC366_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDF2578214.1"
                     /translation="MGKTKDVIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFALSYVLTIRPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKAI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLLVSILTVISSYGVDVPVV
                     KSLPLHSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
BASE COUNT         9508 a         2224 c         3980 g         7262 t
ORIGIN      
        1 atagcaaatt tttagggtat aatttttaaa attatattct actatcaaaa gatatgaata
       61 aatgattgta tatattatat caatttttat atttcatagt ccattttttc atcacatttt
      121 cgcttgtcaa gaataatatc tttaagagtg aagcgtttga tgtaaatctg gactttgttt
      181 ttgagacatt tttgaaatat ttattaaatc cttcgattat acttgtaata tatattatag
      241 atattactta ttttagtaaa actaaaggct gatgctacaa cattccagtt atttccaaac
      301 gttttaattt ctgaagtata ctgtttacat tatttttaat ctattttatc taaagtcgat
      361 aaggcttttt attcattaac tgacctatat acagatttaa aatcacttat taattctttt
      421 gagtccttgt atgaaacata tttaaagtat ttcttatcta atgtattaaa catttttgta
      481 ttacagaatg aggataactt gtagctattg tctctttgaa ataagtcatc tgtatttact
      541 cctaaaacta cttatatctg tagattttat aagttctcca tcttatataa tttctttgat
      601 taattgtttt cttaaattat tcataaaaaa atctccgtta cgatatttga ttatatttaa
      661 atcattgcca taaagaagac ttttattaac tttgaaaaac aaattatttt acattactgg
      721 tgattagttg ctactttctt ttgatattaa ttctattaga ttttatatag ttatatatct
      781 ctttctaact aagtaatata atattactgt tatagtagct actaatatta ttgctattat
      841 tgtaatatct aatcttcttg taaataagcc tattgatata tactcaagac ctgttacata
      901 gcgataaagt acttctagtt taacagtttt tttcttatct atatttccat atattgattc
      961 taatttatta aaatattttt tactacaaaa agcagtttta ggtttaatta aatatattat
     1021 tgtagttcct attataacta ttattccaat aagtataaga ttgatatttc caaaatccat
     1081 agcagatacc tcctgttaaa tttacttttc ttaatcaaag tatatcagta acacaagtat
     1141 aaagagtatc taaaatatta caaatattaa atgagaaaaa gatggtaggt taaccccacc
     1201 atcttatttt ttatctatta ataaatgatg ctacaaaagt tagtataaaa aatgaaacaa
     1261 acaatataat gaacttgtgt aatttactta gttgaaatac tttattacaa aagaataaaa
     1321 ctagtgctga gataattgca aaaagtagat attttataat cattttatca cctattgatt
     1381 tcttacagat tgtaagtaat atttggttac ataagcccca cctttattat aacgcatttt
     1441 tttaaattta aagatttttc cagatgttat atttgaacca agatgcattg taattgctcc
     1501 aactatagca gctgcaagat actgtcctat accaggaatg gcaccagcca aaagccctgc
     1561 aacccctgta ccagcaccag ctaaagttaa tgcaactcct ttagaaagat ataaatcaaa
     1621 gcctgtctta gtccaaacta ttttatttgt tccagctttt ctataatata attcattttc
     1681 aataagagta gtgtcgatac cattttcctt aaggttttta attagcttat taatatctat
     1741 gtatgtaact gtacctggtt taggtaattg agagtcattg atttccaagt cttctattgt
     1801 tgttggattg ttttctatat aacttgggac gttatttgaa atttccattg cattggctgt
     1861 ttgtccaata ggtataccta taagagctgc taataatgct actgataaca atttcttaat
     1921 ctttggattt cttagtttca taaaatacct ccattttaaa ttagttatat atcaaagata
     1981 tatattatta ttgtagaata taattcttaa gaattaacta cattaaatat taataaaaaa
     2041 tatagtaaaa cttaagaata catataataa aacttaatat aaattaagta tatgaaataa
     2101 atatcctgta tttaagctta tagattataa tgaaatataa tacatattat aataataaaa
     2161 cgaactaaaa ttatcacact aaagcataaa acatactcta atcatgttag ataaattttt
     2221 gaatatataa tccaaaagta ctctctaaag tagagtactt cttttttatt aattattttt
     2281 atatggaata aattggaata ttatatttgt tccaatctga ttgattacat actattatta
     2341 gtataaaatt taattataca taaattggta agaggtgtaa actaatgaag attaataaat
     2401 taccacatgc agaactaaaa ctaatgaagt atatttgggg agcagatgat gtattagcct
     2461 caagagatat catagaagca atgaagttga aatacgattg gaaaaagagc acaacattga
     2521 catttttaaa aactttagta gataagggat ttttaactac ttattaaggt agatagatgt
     2581 acgcattata ctatagctat aaaagagaaa gattacttaa aagttgagac aaagagtttt
     2641 tttagtttta tgcataacaa ttcatttaag agttttattt cagcactaca tgatgatgaa
     2701 gttttagata gtaagagctt ggacaaatta gaagaatact ttaaaaattt gaaagaagaa
     2761 gatattgatg actaataaag ctatcagtat ctttttagtt tgagacaatt gagagtagcg
     2821 tttggattta atgttagttt tatgtgatgg taaaacatta tataaagaaa agtgattatt
     2881 tccttagtgt ttgatagtaa aaaatataga gaataatacc aattaaaatt taaagatata
     2941 tgaaatacta caatagctta aatcatgtaa atatgataaa gatattgaaa ttataaaagg
     3001 aatataattt tagaagaaat agttgacaga taaattacct tactatatta ttgtattaat
     3061 aaaataatac aataatatag taaggaggta ataaatgaaa tctagaaaac ataatattac
     3121 aaaaggatta tttatagttt acataattat tttaacatgg ataatactat ttaagttgca
     3181 atttgatatc tcatctcttg aaaccatgaa tcttagaagc ataaacttag taccttttgc
     3241 tgggtcactt ataattaata atagagtaga tatatcagag attatattaa atgtggctat
     3301 atttgtacca tttgggatat atgtgtgtat gctaaaagaa gaatggagct ttataaaaaa
     3361 agttatacct atttttataa ctagtttagc atttgaaaca cttcagtata tatttgcact
     3421 aggtgcaagt gatataaccg atttgatagg aaacacacta ggaggaatca taggaatagc
     3481 tgtttttatg ctattatcga aaatatttaa gaataatacc ataaaaatta tcaatgtatt
     3541 ggcattgatt gtgacaatta ttgttgtatt atttttagga ttagttattt ttgcaaactt
     3601 atagaaataa gtatataggt ttagcttaaa atagaacgta agatacagtt acatataaaa
     3661 ttatttacac ataaaaagca cctatatagg tgctttccta aattattaaa gaattattgt
     3721 atcttgaaac tctcgtatgt tcaattcttg attttctctt gttttttcta ataaatctaa
     3781 tgcacaattt atacaaactt taatttctgc attggtattt ttctcataat aagttatata
     3841 tttatttcta tatttatcta tttcttttcc acaacgacta cacattacaa ttacgctcat
     3901 atcttagttc ctccatctct aattattctt aatatattca atagtatcac ttttctgaaa
     3961 ataatgattg ttaaaactgt atcaaattta gatttacttt ttattataat gcattttaat
     4021 aaaaaaataa aggttatggg taaaatattt atagaaaaaa gtatattatt gaatagatta
     4081 taaaatttta ttatttttca tcagtcttaa atacacatta atatctataa aatgacaaaa
     4141 taaaaaatac tatttaaata gagattaaaa aattgatgcg aagtatttgt ttgctatatg
     4201 aataacaatt tatttagaag ttttgatttg acactgtata ataataaagt aattgctaaa
     4261 aaagtttgat gatttggatg tatttttaga aattagaaaa atatatactt actgactaat
     4321 gataatctta tatatatttt agtttgagtg atttaagaaa agtgttttga aaggggatta
     4381 ttttatagaa taaatatata tatatagtag aaaattacat ataaagagta gtatttattt
     4441 cattaccttc tttatctgtt ccgatggggt cttgtagaga tacttgagtt ttattttttt
     4501 tgttagatct aatattcatt aaaatctcat tttcaataca tctagaagca tatgttgcta
     4561 atcgagttcc cttatctatg ttataagttt ctatagcttt aattaatcct attgtaccta
     4621 tggatattaa atcatcctga tcttccgttg aattattata tttctttgct atataagcta
     4681 ctaatctcat gtttctttca attaatgtat cttttgcact tttatcgttt tctattttaa
     4741 atttagttaa atactcaatc tcttcttcag gggttaaggg tttttcaaaa gatttaagag
     4801 ctgccaatag gtcaccccct tttcaacggt cactttaaat tatatgaagg agacttatcc
     4861 aagttgactg ttatctaata aaataatatg catattttta gaatttaaaa catatatttg
     4921 caaacttttg aatggaatat gacataaaga gtgggaattt aaatttaagt ttttgttgta
     4981 tatatatgaa acaaggcgaa gaaattattg atttataaag tataaattgg aattgaggtg
     5041 tcaataaata taaaaggaaa tagtatttat atatgttttg gtgttgaggt aaaagattaa
     5101 tgcaaagcat tagagtctat aaaaatatga atataggagg tgtaatttta caatacttaa
     5161 aaaagtaaat gtaattaatt gtttgtataa agttgattac aagcaaaaag tatcagtcat
     5221 agttaattct gttaaggatg aaggtggtgt gttaatttat atatgtatgg gaagaaattt
     5281 tgattacaat gaaaaaactt acaaaagata tttatgaaaa aacttatagt taaatgttta
     5341 tatataaaat attatttagg ggttgttttt attattgaaa ataagaaaga gtggttttat
     5401 atcaatcgaa tgtataataa gtattgctat attatatgtg gctgtttatt tagtttctac
     5461 atcattgtat aattgttata gttttatcag tagaaatata tctgacagag aaatgttaag
     5521 tacagcaaaa aaatatatag aagatgagaa gtatagaata caaaatagta agtatgagtt
     5581 aattgaagat aagatagaaa aaaattacat aaatggatat gaaattaaca gtagaataga
     5641 gcaaatttta gattattatc aatgctatga aataaatata gagataaaaa atgaatttaa
     5701 aaaactgagg tttaatagct atgttactag aaaataaagg ctctatatta ataataacat
     5761 tgataatatt ttctattata agtactgtgt gcattatgtg tataggttta atttatacac
     5821 ataataatat gtttgagtta ggatacaagg acattcaact aaaagaaatt tctttaagtg
     5881 gaatagaaat atcagtaagt aatgtacttt cttgtgttga ggaagctatt gatgtatcta
     5941 ataatgaaga cgaatttaga gaatatttct taggaaataa tatgattgaa tgtataaaaa
     6001 aaataaaaga tacatcttat agtagtttag aagaactttc tttaaaagta gaaaataata
     6061 ctatttatga cagaggagat ttttttgaat ttgatataga aagtaatgtt agagaaaaag
     6121 aatttttaaa agcaataaaa gtaagagtga aaatcaaaaa tccatggata ggaattgaca
     6181 ttgaagatta tatggataaa tctaataaca ataaaattga tgacaaaaca ttcaataatt
     6241 ataaagcatc tgaaaataat gaaattctaa atcaatttaa aaatgaaagt gaaaatataa
     6301 ggaatcaaga ggttgttgaa tttacagaag aagatgaaga atatgaagaa gaacttaaac
     6361 aaaacataat tgaaaatata aagaagaatt ttgatgaaaa aaaactagta caggtatata
     6421 agtatagggg tgtataactt tgaaaaaaga aggaatgtga ctgtaataga attaatagta
     6481 tctatcagta taatactctt gatagttaca ttatcttttc caaaagataa tcttgaaaat
     6541 cataaaataa atttatttgc acgtcaactt tgttcagata taaggtatgt taggcgaatt
     6601 aatatgttta gcaactacaa tacatatata tattatataa atcaaggtaa acacgaaggt
     6661 tatgtattga gaaaagatgg taaaaacatt aaatcaataa tgctacctaa aaatgcaaaa
     6721 atagctagaa gtattgaaat aataaagttt aaatctgatg ggtcgcctca aaaggcgtct
     6781 acaatagaga tatataataa tagattaaga aaaactataa caataacacc tgtaagtgga
     6841 agagtacttc tgaaagaggg aaaatatgaa acataaatat ggttacttgc ttttggaaag
     6901 tgtagtatca ttgtcttcaa tggtgataat tatactagtt ttatattcta tatttttgtc
     6961 tacaataaac ttaaagttaa aagtagaaga taagatagaa ctacaacaac aaagtcttga
     7021 aatcataaaa tctatggaag gaattattag caattctatg ggaataatga atgtatctaa
     7081 ttatgaagaa acatttaaaa agacaacgtc tataaaatgt agatatgtag atgaaaataa
     7141 taatgaagaa agcataagta ataaagaaat tatattgaat gaaagacgaa ataagttatt
     7201 tgtaaattct ttaaatggcg aaagtagtca agcaggtggt tatgaaattg gagattatgt
     7261 agatgagatg tatgtattaa ttactaataa tggtcaatat gttaatatta aattgaaatt
     7321 atcaaaacgt agtcaaaaat atgagactga tttcaaaata aaagtatgga attttagtga
     7381 aagtatataa aaatacataa atttaagata aagaaatgac atcaataagt catataaaat
     7441 ataattattg agaactatat aactaaataa tatcaatatg taaagtgtat agattaagaa
     7501 tatagaggat aataataaaa atatagaata agtaatttgc caaatacttg tttatattgt
     7561 ataacttatg atattatgat attagtaaaa atttgtaatc ctgacttgac agaattcaag
     7621 taagagatat aattttaaag gcatagtaat gtaaaattta ctaaaaaata agaaatttat
     7681 tttaatatgg aggaacaaaa aatggtatca gcaggtgatt ttagaaaagg tgttacattt
     7741 gaaaaagatg gacaaccatg tttagtagtt gattttcaac acgttaagcc aggtaaagga
     7801 gctgctttcg ttagaactaa atacaaaaac ttaaaaacag gagctataag agaagaaagt
     7861 ttcaatccaa gtgaaaaatt ccctaaggct gttatagata caagacaaat gcaatatcta
     7921 tacaatgatg gtgagttata ttattttatg gatcaagaaa attttgaaca aataccatta
     7981 aactatgagc aagttgaaga tgcaattaag ttcttaaaag aaaatgaagt tgctacaata
     8041 agattttacc aaggacaacc attccaagtg gaagcgccaa actttgcaga gctagaagtt
     8101 acagatacag agccaggtat aaaaggtgat acagcaagta atgtaactaa agcagctaca
     8161 gttgaaactg gagcagttgt tcaagttcca ttatttataa atactggaga taaagtaaag
     8221 atagatacta gaacaggtga atatttatca agagtataaa aatttatgta tataaaagct
     8281 tatatgtctt aataatataa gatatatgag cttttagttt atatataaaa aagaaagcga
     8341 ggggtgttac atgaaacatt tatatgaaga agttgcatac ttaaaaggcc tagcagaagg
     8401 actagaaata agtgctgaaa gtaaagaagg gaaaatgata cataaaatag ttgatgcatt
     8461 agaagtattt gcagatgcta ttgtaacatt ggatgaagaa caagaagaac ttcaagattt
     8521 tgttgaatct atagatgaag atttagcaga tttagaagaa gatattgctg acatggaaga
     8581 agatctttat gaagaagatg acgatgagga tgatgaggac ttcagctata tagaaatgga
     8641 atgcccaaat tgtggagagt tagtagaaat agacgaagat ttgttatatg atgatgaagt
     8701 agatgttgtt tgtcctgatt gtaaggctgt gatattatca tcagaagatg attgtgatga
     8761 tgattgtaca tgtggtggtt gtccaagttg tgatgataga gagtaaaaat tcataagaat
     8821 taaaactgcc tatgatgcct atgagatatt ttgcttcata ggtagtttta tttttatgag
     8881 gaagggtatt atgtattttg gttttgcaat acttggacaa aaatagtaca ctagaattta
     8941 tagaatagga ttttggaggg atgtaaatat gaaaataagt aaaaaattac tagataatat
     9001 acaaagattt gaaaatgtta taaattataa atttaaaaat aaagaatata tactagaagc
     9061 tcttactcat agttcatatt ctaatgaaaa taaaaaatat aattttaacg aaaggttgga
     9121 atttttaggg gattcggttt taggcatagt gataagtgat tatttattta atgaagaagc
     9181 taatctgccc gaaggggaac taactaaact tagagcaaat atagtttgtg aagattcgtt
     9241 aagtgaagta gctaatgata taaatttagg tattcatatg ttattaggta gaggagaaga
     9301 agcaacagga ggaagacata ggacttcaat attagcagac gcatttgaag ctgtaatagc
     9361 tgctatatat cttgatggag gttttgaaag tgcaagacag tttatacttc atcatatgga
     9421 aaatataatt tatgattcaa gaaaaggaaa tatatttaga gactacaaaa cgcatcttca
     9481 agaagtgtta caagggaatg gagaaaataa tatctggtac aggcttatag aagaaaaagg
     9541 accagaccat aataaaagat ttgtaatgga agttggaatt aatgacgatg tattgggtat
     9601 aggagaagga aagagtaaaa aagaagctga acagttagct gctaaaatag ctttaaagaa
     9661 aaaattatgg gaaaaataaa tataatatgt aaaaatataa aaagaaatat ttatattaga
     9721 aggatgttgt agatgaaaaa gagaattata cctatatttg ttcctcacaa aggatgtcct
     9781 catgattgca tattttgtaa tcaaaaaaaa ataacaggtg tgagtactga tgttactagt
     9841 gaagatgcaa gaaatataat tgaggaatgt ttagagacta tagataaaga tgcagatgta
     9901 gaaatagcat tttttggtgg tagctttact gctatagata ttgatataca aaaaagttta
     9961 ttatcagttg ctaaagaata tgtagaaaaa ggtcttgtaa aagatattag aatgtctaca
    10021 agaccagatt gtattgatga agatatatta agtatgctaa aagaatataa gacaagtata
    10081 attgaactag gagtacaatc cttagatgaa aaagtattat tagatagtat aagaggtcat
    10141 caatctgaaa ttgtatacaa gagttcaaag atgataaaaa atagtggaat caaacttgga
    10201 ttacagatga tgattggtct tccagctgac acagaagaaa agtgtatatt tacagcaaaa
    10261 aaatttgtag agctaaaacc agattgtgtt agagtctatc caactttggt agtaaaagat
    10321 acaggtcttg aaaagttaat ggaacaaaat aaatataatc catttactct tgaagagagt
    10381 gtaaatatag taaaaaaagt tcttgtactg ttttatgtta ataatatcaa tgtaataaga
    10441 gttgggcttc aagctactga tgatatacaa attggaaaag ctgttttagc aggaccatat
    10501 catcctgcat ttagagagtt ggtagaagca gatatgataa aagattattt agaatttgtt
    10561 attttgcaaa ataaaaatat aaagcaaatg ttggtcaaat ctaataaaaa gaatatttct
    10621 aaaatcatag gaaataaaaa aacaaatgtt aaatatatgg aagaaaaatt tggtgtgctt
    10681 ttaaaaacac aagaatccga tttagatata aatcaattag aaattgtgtt agatgggaaa
    10741 agtttaatta gtgctaatat gagagacatt catagaaaat tgtatgacat ttatgacctt
    10801 tagttttaat aatgaaggga gagaaaagat ttgtatttaa aaagactaga gttaaaggga
    10861 tttaaatcct ttccagtaaa aacagatatt atttttaaag aaggaataac agccatagta
    10921 ggaccaaatg ggagtggaaa aagtaatata tctgatgctg taagatgggt attaggagaa
    10981 cagagtatta agagtcttag aggtgataaa ctcgaagatg taatatttgc aggtacagat
    11041 acaaaaaaac ctatgaatta ttgtgaagtg gctcttacta ttgataattc tgaaaatcaa
    11101 ttggaattag attttacaga agtaactata agaagaaggg cttatagaaa tggtgaaagt
    11161 gaattttttc taaataataa aagttgtaga ttaaaagata taaaagaagt ctttttagat
    11221 actggtattg gaaaagatgg ttattcaatc atagaacaag gaaaagtaga tgaaatatta
    11281 agtaataatc ctttaagcag aagaaaagtt tttgatgaag cttgtggcat atcaaaatat
    11341 agatataaaa aacaggaagc agaaaggaat ttaagtaata caaaggaaaa tttagaaaga
    11401 atagatgatg tatatataga aattgaaaat caattaaagc ctctttttaa tcaacagaca
    11461 aaggcaaaaa agtacttgga aataagtgaa aaattaaaga tacttgaagt aaatagcttt
    11521 ataagagaaa ttgaaggaat agaaaaagaa ttaagtgagg ttaatgaaca tcgtaaggtt
    11581 attgaaaagg agctcaatga aaaagaagaa caaaaaaatg ttgtagagaa aaagcaagaa
    11641 gatattaata aagaggtaga ggtattacaa gatgtaattg aaaaatctgt agattatata
    11701 aattcaatta aaggagttat atcaaaaaaa gagtcccaaa taaatttaat taaggaaaga
    11761 ataagaaatt ttacgaatga aattagtaga aaaaatttag aaataaatga tataaaagag
    11821 aagctaaatg aaaataagca atacataaaa gaattagaaa gtaataaatt atcaggtagt
    11881 gaagaactat ctaccttgca ggaaaatata aaagtattgg aggcaagtaa agataaacaa
    11941 aaaattaagt tagaatccct aaataatgag atagaattat tgaaagaaag tataattgat
    12001 atattaaata agaaacaaga gtttagtaat aagctgtcca ctttaaacgc aaataaagaa
    12061 aatatgaata tcagagatga aaatataaat tcagagataa cagagttaaa caaaaatatt
    12121 gaaataaaat catctgaatt agatactata aataaagaat ttaatatgca aaatgaaaat
    12181 ttaaagaatg taaataatag acataaagaa ttatcaatta atttgcagga ttcaattagt
    12241 gaacacaata aactagaaga tgaaatacag aaaagtaaat ataatttaaa tggatataat
    12301 tcaaagttaa atgtctatat agatatggaa aatcattatg aaggatttaa tagaggagta
    12361 aaagaagtac taaaaaataa aaatttaaaa ggagttcatg gagcattagg acaaattata
    12421 aatgtacctg aaaaatatga gaaatctata gaagcagctc ttggtgctta tatgcaaaat
    12481 ataataactg ataatgagtt tagtgctaag tctgcaataa actatctaaa acagaataat
    12541 ttaggtagag taacatttct tccattaaat ataattaaat caaataaagt aagtctagga
    12601 aatttaaaag caaatactaa gttcatagga atagcaagtg atttaattac atttgatgaa
    12661 aagtatagaa atataattga aaatatactt ggaagaacaa tacttataaa taatatagat
    12721 gagggcataa aatttgcaaa agaaactggt cataggttta aaatagtaac tttagatggt
    12781 gaaatcttaa atccaggagg ttctttgact gggggaagtc taaaaactaa tgggaatata
    12841 ctatcgagaa aaagatacat taatgaatat acagaaaaga taagtaatat caagaatgaa
    12901 atttcacatc tagaattaaa aagagaatct ttagacaaag atgtgaaaaa tatcaaaaat
    12961 gaaattgatt cacatgaaag taaaataaaa gatttagaaa aaagtataat aataaaaagt
    13021 acaagtataa agaatgttga atctgaaatt gaatcgttaa aaggtagtat tactaaatta
    13081 gaaaatgaga agaatgattt aaattctaat ctaaattata cacttgaaaa aagcgatgat
    13141 gttagaaaag atatggaaga gttagatgat ttatacaata aaaataaaga aaaaattgat
    13201 gcattgaatg aggaaataaa aagatacaat gatttatatg ataaagaaaa atctgaattt
    13261 gatgaattga acttaagttt agtgaagaaa acagaagctt ataatagtat agttagagat
    13321 ataaaaagaa tatctggtga aaattgtgag ctagaagaaa agaataaaca attagaagag
    13381 tcattaaatt atgaagaaca tgaaataatt aaattacaag attctatagc cactgaagaa
    13441 aaagaaaaag aaaatttaac aaaacaacta ggggatagta atagaaatct tgaaactaga
    13501 aaaatagcaa aagatgattt aaaaaatagt tttgatgaaa ttaataaaga attaaaaact
    13561 atagatagac agcatataga gcttaaagaa agtttattta aagttggtgg aagattagaa
    13621 agattaaaaa ctagtcaaga cacatatata aataagttgt ttgagcaata tgatatgact
    13681 ttagtacaag cattggaaat taaagatgaa gatttggata tagatagaaa attcttagaa
    13741 agtctaaaga gagaaataag aagtcttgga aatataaata taggctctat aaaggaatat
    13801 gaggaaataa aagaaagata cgatttttat agcgaacaaa agcaagattt agaagagtct
    13861 atggaagaga tagaaaaact tatacacact ttagaagaaa atatgaaatc tgaatttgaa
    13921 attaagtttg aagaaataag taaaaatttt aaatatgtat ataagagatt atttggtgga
    13981 ggttgtggag aattaactat tttagataaa gaaaatttat tagaaagtga tatactaata
    14041 acagctcaac ctccagggaa aaaaatgaaa aatttaaatc tattatctgg tggagagaaa
    14101 gctttaacag caataagtat attatttgct atattgatta caaagccaac accattttgt
    14161 atattagatg agattgaagc gccacttgat gatgcaaata tatttagatt tggagaattt
    14221 ttgaaggatt tatctaaaga gactcaattt atatcagtaa ctcataggag aggaactatg
    14281 gaagctgctg attatatcta tggagttaca atgcaagaaa aagccatttc aaaagttatt
    14341 agcttaaaat taaaagaagc tcaggaaata acagatatta tataacttag attgacatag
    14401 gaggaataac agtgttaaaa aaattatttg gttttggaaa agacaaggaa aaagaaatag
    14461 aaaaaaaaga tgctgaagaa gaaatagaag ttgaagacag tgttgatagt ttagaaaact
    14521 tggaagaaac cattttttca ggacttgaag aagaagtgat agataaagtg gaagatattg
    14581 aagaaaaaac tgaggaaagt gtcaataatg aaggcactga agaaatcgaa aattttgaaa
    14641 aaatagaagt tgagatggat agtaatgcaa aagaagtaga aaatatttca aataatgatt
    14701 ctcaagaaga gataatcgaa gaattagaaa attatgatga aattgagtct aaagagatag
    14761 aagataaaga agataagaaa gttaacttgt ttgaaagact aaaacaagga ttgacaaaag
    14821 caaagcaagg aataactgat agaatagatg aagttttaaa atcatataca aaaatagatg
    14881 aagaattact tgaagattta gaggaaattt taataacagc agatgttggt gtaaatacaa
    14941 ctatggatat aattgaaaga ctaagagata aaataaagca aaaaggtatt actgaaccaa
    15001 taaaggtaag agaagaactt aaatctatag ttgaagatat tcttacaaat gaaaactcta
    15061 cactagatat agaaccagca ccatgtataa tattaatggt gggtgtaaat ggggtcggta
    15121 agactactac aataggtaaa ctagcaaata gatacaaaaa agatggtaaa aaagttttat
    15181 tagcagcagc agatacattt agagcagcag caacagagca attagaaatt tgggcaaata
    15241 gaaccaatgt agacataata aaacatcaag agggagcaga ccctggagct gtagtatttg
    15301 atgctataaa agctgcaaaa gctagaaaaa cagatgtatt aatatgtgat acagcaggaa
    15361 gattacacaa taaggctaat cttatgaatg aacttggaaa agtatttaaa atagtagata
    15421 gagaatttcc agaagcaaaa cgtgaagtac ttcttgtggt ggatgctaca acaggtcaaa
    15481 atgcagttgt tcaagcaaag acatttaaag aagttgcaga tataacaggt atagtactta
    15541 caaaacttga tggaactgca aaaggtggag tagtccttgc agtaaaatca gaagtagatg
    15601 tacctgtaaa acttattgga gttggagaaa gtgtagaaga cctacaagat ttcaatgcaa
    15661 aatcattttc agatgcatta tttggtaact aatgttcttt taaaaataat ggttgacaag
    15721 agtgttgtta tgatataaaa tacaatagtg taaagtaaat aacctttaca gtatactgct
    15781 aggaagtgta agatatgaat atagaaaaaa tggtcgaaat tggattgtta tttgaacagt
    15841 ataaagaatt attaactgac aagcagaaag aaatagttgc tctatactat gaagaagatt
    15901 attctttagg tgaaattagt gaaaatctga atgtatcaag acaaggtgtt tatgatacct
    15961 taaagcgttc agaaaaaata ctaagagatt atgaagaaaa gttacactta gtatcaaaga
    16021 ttcaagagca ggaaaaaaat attaagatta taaaagataa aattattgac attaaagaag
    16081 atttattgca caatagagat tgtgctaatt taatccctaa gctagaaaat atagaagatg
    16141 tatgtaggga gatgataaaa tgatatttga aggattgtct gataaactac aaggggcatt
    16201 tagtaagtta aaatctaaag gaaaacttac agaagtagat gtaaaaaatg ctatgagaga
    16261 agttaaactt gctcttcttg aggcagatgt taactttaaa gtagttaaag atttcataaa
    16321 aaaagttcaa gagagatgtg ttggacaaga agttatgcaa agcttaactc cagctcagca
    16381 tgtaatcaaa attgtaaatg aagagcttac aagtttaatg ggagatgtac aaagtaaagt
    16441 aatgatttcc tcaaagcctc ctacaatttt aatgatggtt ggattgcaag gtgcaggtaa
    16501 gactactaca gcaggaaaac ttggaggata ttttaaaaag caaggtaaaa aacctctatt
    16561 agtagcttgt gatatttata gaccggcagc tataaagcaa cttcaagttg ttggagaaaa
    16621 attggatata cctgtattca atatgggaga taaagaaaat ccagtaaata ttgcgaaagc
    16681 aggtttaagc catgcgatta aaaatgctaa tgatttagtt attatagata cagctggtag
    16741 acttcatata gatgaagtac ttatggctga gttaaagtct attaaatcag aagttaagcc
    16801 acatgagata cttttggttg tagattctat gacaggtcaa gatgctgtaa atgttgcaga
    16861 aagcttcaat gaggcacttg gtgttgatgg agtagtatta actaaattgg atggagatac
    16921 tagaggtggt gctgcacttt caataagagc agttacacaa aagcctataa aatttatggg
    16981 gatgggagaa aagctagatg atatagaacc tttccaccca gatagaatgg catcaagaat
    17041 attaggtatg ggagatgtct taagtttaat agaaaaagca caagaaaata tagacttaga
    17101 gaaagctaaa gaattagagc aaaaaattaa aaaacaagag cttgattttg aagatttctt
    17161 acaacaaatg gaacaaatac aaaatatggg acctcttgac aagatacttg gtatgatacc
    17221 tggtatggga aatgtaaaag accaacttgg agatgtagat ttgaatggca aagaaatgaa
    17281 gagaacaaaa gccataattc agtcaatgac tacatatgag agaagaaacc caggagtatt
    17341 aaatgcttca agaaagaaaa gaatagctaa gggcagtgga actagtgtac aagatgtaaa
    17401 tagacttata aaacaactta atgaaatgaa aaaaatgatg aagatgtttg ctggttcaca
    17461 aaagagtatg aagaaaaggg gcggcttagg cggtttacct ttttttaaat aaaatataaa
    17521 aaagtaaaaa ttattcggag gtgactgtaa tggcagttaa aataagatta aaaagaatgg
    17581 gagctaacaa aaaacctttc tacagaatag tagtagctga ttcaagagct ccaagagatg
    17641 gaaaatttat agaagaaata ggatactata atccaatttc tgaacctaaa caagtaagaa
    17701 taaatgatga aaaagctata aaatggttag ctactggtgc tcagccaaca gaagtagtta
    17761 aaaaattact tgtaaaaaac ggagtaatag aaaaattcga agcttctaaa caagcaaaat
    17821 aattttttct tggcaattag tttaagtaag ggctcattgc taaggttact ttaggagatg
    17881 aaatatatga aagagctagt tgtagatata gctaaggctc tagttgataa tcctgactca
    17941 gttgttgttg aggaatttga agataatgat ggtatcgtct taaagcttac agttgctcaa
    18001 gaggatatgg gtaaggttat tgggaagcag ggaagaatag ctaaagctat aagaactgtc
    18061 gtaagatctg ttgcaaatag agaaaatata aaagtttctc ttgagatagt ataaaatagg
    18121 aggattaggt ataatgccta gtccttttta tataaatgcg tagtttaaga ttttatgatg
    18181 atatgaccac ataagattaa attttttaag aaggtgataa catgaaagaa aaattaactc
    18241 attttaaggt aggtcaaata gtaaatacac aaggtttaaa aggtgaagta agagtttatc
    18301 cacttactga tgatatagag aggtttgatg aattaaaaga tttctatctg ggaaaagatt
    18361 taaataataa attggctgtt gaaaaagtaa gatacaaagg ttctatggtt ataatgaaga
    18421 taaaaggcat agacagcata gagaaagcag aaaaactaaa aaataaattt atgtatgtat
    18481 ctagagaaga tagcagagag cttgaagaag gcgaattttt tatagcagat atgattggaa
    18541 tggaagtttt aactgtagat ggaaaatatg taggaatact agaagatgtt cttcaatact
    18601 cagcaaatga tgtttatgta gtaaaaggtg aagaagataa agaatttatg ataccagcta
    18661 taaaaaaatt tgtacctaca atagatattg atgaaagaaa aatgattata gaccctatta
    18721 agggaatgat agattaggtg gtaatatgag atttcatata atgacacttt ttccagaaat
    18781 atttaattcg tacatggatg aaagtataat gaagagagca gttgaaaaag gtataattga
    18841 ggtttatata tataatataa gggatttttc taataataaa cataaaaaag tagatgatta
    18901 tccatttgga ggaggagtgg ggatggtaat gactcctcaa cctatatatg acacatataa
    18961 gcatataata acaactcaca atataagtaa tccaagtgta atttatctta ctccaaaagg
    19021 taaggtatac aatcaatcta tagcaaagca gatgtcttta aaagaagata taatactatt
    19081 atgtggccat tatgaaggag tagatgagag aatcattgat ttaatagtta ctgatgaaat
    19141 ttcaattgga gattatgtat taactggggg agagctccca gcacttataa tgatagattc
    19201 tatatcaaga ttaataccag gtgtattaaa ccaagaagaa tcatttgaag aagaatcatt
    19261 taaagataac ttattggaat atcctcatta cactagacct agagattttg aaggattaaa
    19321 agtaccagaa gtgcttttat cagggaatca taaaaagata gatgagtgga gaagagaaga
    19381 atctataagg ataaccaaag aaagacgatt tgatttatat aaaaagtcta atgaaaaata
    19441 aaaatataat gaaaaattaa tatatatgta tacaataaag tacctataaa tggaattaaa
    19501 aacataaaag tgcttgtaat aactattgaa gtatagtata atataaaatg ttgaaaatac
    19561 gggcgttcct ctgtttacac tggtcgggta gttaagaacg tctatgatat ctaggaggaa
    19621 gaaagatgaa tgaaatgcta agagcaattg agcaagaaca attaaaaaat gaagttccta
    19681 attttggacc tggggacaca gttaaagtac acgttagaat tatagaagga aaaagagaaa
    19741 gaatacaagt attcgaaggt gtagtattaa agagacaagg tggaggagca agagaaactt
    19801 tcacagttag aaaaatgtct ttcaatgttg gtgtagaaag aactttccca gttcactctc
    19861 caaaaataga aaaaatagaa gttactagaa aaggtaaagt aagaagagct aaactaaact
    19921 acttaagagg tagagtaggt aaagctgcta agataaaaga agctagaaat aaataattaa
    19981 aaactttact tataaatggg gggctgattt atcagtcctc tttctatttt aatgaaaatt
    20041 acagcaaata attatactag aaataaatag aaatatttgt tgaaaatata cattatttat
    20101 ctatgaattt atagctttta aaatgaaaaa taaaattggt aaatattgga ttatattttg
    20161 taacgatatt aaaaataaga gaacagtatt atgtaaagta tgacgttaaa aagatgacaa
    20221 tattatagtt tgtgaagata gattttttaa gtggaattag aatataataa tataatatta
    20281 ataaggagtg atacatgtgt caaatgaata cgaagagtat cttatggatg acaatctaca
    20341 tataaactgg tatccaggtc atatgaaaaa aactaaggag ttagtaaaaa ataacttaaa
    20401 attgattgat gtagtaattg aacttttgga tgctagaatc ccgtttagta gtaaaaatcc
    20461 agacatagac aggcttgtag gagataagcc aagagttgtc gtacttaata agagtgatat
    20521 ggcagatagg gataaattga atcaatggat tgaatactat aagaaaatta atatcaaagc
    20581 tataccagta gatacaataa aaggtgttgg tataaataat ataatcgaag aatgtaaaaa
    20641 tgtaactaga gaaaaaatga gttctttaaa agacaaaggg agaaaagaaa gagctatacg
    20701 aataatgata gttggagttc caaacgttgg taaatcgtct cttataaaca aattaacagg
    20761 tagaaaaagc actcaaactg gagataagcc aggagtaacg aaagggaaac aatgggttag
    20821 attaaaggga aatcttgaac ttttagatac acctggaata ctttggccta agtttgaaga
    20881 ccaagaagtt gcattaaatt tagcatttag tagagctata aaggatgaga ttttagatac
    20941 tgagactttg gctttaagac ttatagaaaa acttatgaaa atagaacctg agaagttgaa
    21001 agccagatat aagttagatt gtctaggaga aactccaatt gaaactatgg atatgattgg
    21061 ccataaaaga gggtttataa caggtaaaaa agaactagat tatacacgca tagccgcaac
    21121 tgtattaaat gaatttagag atggaaaaat aggaaatata acattggaag ttccagaaaa
    21181 cgttaaaaga tagattttaa aacaaaatca aagatttaat gttaaaaaaa taaaaaagcc
    21241 ttttagcaaa ggctttttta tttttttgaa atatagacaa atatctccat ataaaagtat
    21301 aaattaggtt agaaaacctt taaaaatatt aatttaagac aaatacacct aatattttga
    21361 aaattaaaat gagtgtgatt attttaaatt ttagcatatt gacttgcttg tttcgtataa
    21421 tatataataa gcacaaataa atacaatata ttaaaaattt aatttattta attttattaa
    21481 tttaataata agttcttatt gtttaattta atttatttat gcaagcgtaa acaatcgaga
    21541 cattttatta atttaataag gttaaaaagg gggattttat aatgggtaag accaaggatg
    21601 ttatagtatt tggatttgcg ttatttgcaa tgttctttgg agcaggtaac ttaatatttc
    21661 caccttactt gggaataatt acaggtccag aatggttaat tgccttctta ggatttacgt
    21721 ttgctgatgc tggattggca cttctagcag taatggctac agctaaattc gatggaaacg
    21781 tagttgaaat gtttaaaaga tgtggtatga agttagggat tcttataggt tgtgcagaca
    21841 ttttatgtat aggtccattc ttagctatac caagaacagg tgcaacaact tatgaaatgg
    21901 gtataatgcc tttatttgga acttcaattc cagtgttatt attctgtata cttttttttg
    21961 cgctttcata tgtactaaca ataagacctt ctaaggtcgt agatatagtt ggacagtttt
    22021 taactccagc tcttttaata gctctagcat ttataattat aaaaggtatt atatcacctc
    22081 ttggagatat agtagataaa cctatgatac ctaatgtatt tgcagaaggt ataggtcaag
    22141 gatatcagac aatggatgct tttgcagcaa tagcacttgc atcagtgtta atagtatctt
    22201 taaatgataa aggatattct actattagtg acaagttaaa aatgattggt aaggcggggg
    22261 ttcttgcttg tggaggatta gctctagttt atggaggatt atgtttcctt ggagcaactg
    22321 tatcaacaat gtatggaaca gatgcagtac aatcacaagt aatagtaaat ataactgaag
    22381 gattacttgg aaatgttggg aaagcgattt tagcagtagt agtatcatta gcatgtttaa
    22441 ctacatctat aggtcttaca tctgccacag gtcaatattt ctctagactt acaaaaggta
    22501 aattgagtta tgaaaaaata gtattagctg tatctgtatt cagtgcagta gtagcatctt
    22561 ttggtgttgg aactataata aagatagcat ctcctatact aagtatagtt tatccaccat
    22621 caattgtttt aataatttta gctttcttca atgaaaaaat taagaatgat aatgtgtaca
    22681 aaggagcagt atatatgtca ttgcttgtaa gtatactaac agttatatct agttatggag
    22741 tagatgttcc agtagtaaaa tctttacctc ttcattcatt aggatttaac tgggtggtac
    22801 cagttataat agctggaata attggtaatt ttataccatc aaagagtcaa tctaatacac
    22861 ttggaacaaa ctaagttttg tttaattaaa atataatcaa ttgtaaataa atgagttaac
    22921 taaaagtaaa aggagttatt tgtacaaata actcctttta ttttgggatt ctat
//
LOCUS       DAMJWO010000069        22348 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.070, whole genome shotgun sequence.
ACCESSION   DAMJWO010000069 DAMJWO010000000
VERSION     DAMJWO010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22348
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.070"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            78..194
                     /gene="rrf"
                     /locus_tag="PC366_002716"
     rRNA            78..194
                     /gene="rrf"
                     /locus_tag="PC366_002716"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            649..1719
                     /locus_tag="PC366_002717"
     CDS             649..1719
                     /locus_tag="PC366_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578215.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGKLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGSPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVVTKEVLGNETIYCLSVLNREIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDVKVCKSMYSKIKGDIYEKAI"
     gene            1703..2572
                     /locus_tag="PC366_002718"
     CDS             1703..2572
                     /locus_tag="PC366_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDF2578216.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            2616..3476
                     /locus_tag="PC366_002719"
     CDS             2616..3476
                     /locus_tag="PC366_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDF2578217.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSMEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLILQFLVMVP
                     AAYAFSKIKFKGEKMLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYIPLIIPFMTS
                     SFGIFLLRQNFMQISDETIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            3507..4811
                     /locus_tag="PC366_002720"
     CDS             3507..4811
                     /locus_tag="PC366_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2578218.1"
                     /translation="MKLKRKLATGLAITLLLGSLVGCSNSNDANASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQERFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INRDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            4874..6136
                     /locus_tag="PC366_002721"
     CDS             4874..6136
                     /locus_tag="PC366_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HDF2578219.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKNLPNFKSILENCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKVKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNRHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNDEVDKALKMNDKWLG
                     DIIQATKDAGTYKDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKDFDAYV
                     NSSGISAQIIVNNLDRLTELRELLEEFKEELFIENIFTKEEASNLGLEGDFEMVIEGL
                     EGISFGNDFEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKGGVVIEEGD
                     LRAHAATILKMFDLKLDGVEKEAFDFIM"
     gene            6323..8293
                     /gene="uvrB"
                     /locus_tag="PC366_002722"
     CDS             6323..8293
                     /gene="uvrB"
                     /locus_tag="PC366_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HDF2578220.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIVEIENELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNIIPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            8312..11137
                     /gene="uvrA"
                     /locus_tag="PC366_002723"
     CDS             8312..11137
                     /gene="uvrA"
                     /locus_tag="PC366_002723"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDF2578221.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLITTLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFASTNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPKEVSKVDGSYTGQFLKKYFS"
     gene            11396..13213
                     /gene="uvrC"
                     /locus_tag="PC366_002724"
     CDS             11396..13213
                     /gene="uvrC"
                     /locus_tag="PC366_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HDF2578222.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSSILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVEAIKKATMEELLEVDGMNKSIADNVYNFFRKEEN"
     gene            13213..14142
                     /locus_tag="PC366_002725"
     CDS             13213..14142
                     /locus_tag="PC366_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HDF2578223.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            14356..16152
                     /locus_tag="PC366_002726"
     CDS             14356..16152
                     /locus_tag="PC366_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HDF2578224.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGFAI
                     GFYNKNIVGIFVGVLSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENVILE
                     RQRAIKELLSKDDFSIHIQILSNIIGKEQKNNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTATILSFIFCMLGFLPVLPVFLLFIIQLGFSGFGYPRLMQTLSPLFSFSRSIQ
                     VYEKMFEVLEKETFESAYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQILYIIA
                     CGVLMWNYHCAEALERWKGIYGNQIRDWFESIGEFEALISLTVISHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSKPWVISMVTTHDFELCDLSGSGDVEVVNYHFSEY
                     YVDDKIHFDYKIKDGRCKTTNAKQLMRMAGIL"
     gene            complement(16292..18073)
                     /locus_tag="PC366_002727"
     CDS             complement(16292..18073)
                     /locus_tag="PC366_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HDF2578225.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRICMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCVYGECPQECACEEAK"
     gene            complement(18096..19982)
                     /locus_tag="PC366_002728"
     CDS             complement(18096..19982)
                     /locus_tag="PC366_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HDF2578226.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            complement(19999..20496)
                     /locus_tag="PC366_002729"
     CDS             complement(19999..20496)
                     /locus_tag="PC366_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HDF2578227.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLTTKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            complement(20814..22295)
                     /gene="cls"
                     /locus_tag="PC366_002730"
     CDS             complement(20814..22295)
                     /gene="cls"
                     /locus_tag="PC366_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDF2578228.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKVGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSICSIGTANMDIRSFELNFEVNAFMYSSKKA
                     LEQRIIFENDILNSKEITLDIYNSRSTYIKIKESISRLLSAVL"
BASE COUNT         8595 a         2998 c         3739 g         7016 t
ORIGIN      
        1 taactctaaa gaaactagta ttactaggtt ctataaactt attaaaaact taatagaaat
       61 attaagcata aagattatgt ggttacaata gcagagagga tacacctgtt cccattccga
      121 acacagaagt taagctctct agcgctgatg gtacttggtg ggaaactgcc tgggagagta
      181 ggacgtagcc acgtaatttt ttttgggtaa atttataaaa attaaaaaag ttttattttt
      241 tatgtttaaa ccttgtaaat ttgggacata atataattgt aaaacttaat atagcaaaaa
      301 taaattactc aatctccccc acttaaagac ctctatcccc catagaggtc ttttttattt
      361 tcaaaccaaa ttatataaaa aataaatagt tttatatgac tcttcataaa ttaaaatcac
      421 attgtgatag caaaccatga atatgaaaaa tatagaaaat tatagctaac ataagctgta
      481 tatcatctta acttcagtat atttaacaaa aaatgtttat aatttaacct ttattttaat
      541 aagtttacta tatattcact ttgtcttaat atatccttta caaattaaga gtattattaa
      601 tctataagta aatcgtagaa ttaaattaaa tattttggga ggataaaaat ggcagatata
      661 agactagaaa atgtaacaaa atcttataat aaaaaaaata cagttataga aaatttaaat
      721 cttactatag aagatggttc ttttacagta ttggtaggtc caagtggatg tggtaaatct
      781 actacattaa gaatgattgc aggtcttgaa gatataactt caggcaagtt aaaaattgaa
      841 gaaaatgacg ttacaaaaac ggatgctagt aaaagggata tagctatggt atttcaaaat
      901 tatgcattat atccacatat gactgttaga gaaaacatag aatttggtct taaaaacaaa
      961 aaagtagaaa aagaaaaaag agaaaaactt ataacagaag ttattgatgt agtaggattg
     1021 agagaatatt taaatgtgaa accaggcaac ttatctggag gtcaaagaca aagagtggca
     1081 cttgctagag ctatggttaa aaatccaaag gtatttttaa tggatgaacc attgtcaaat
     1141 ttagatgcta aattaagaaa tcaaatgaga acagaattaa tacaattaca tcaaaaacta
     1201 aaatctacat ttgtttatgt aactcatgac caggttgagg caatgtcaat ggcagataag
     1261 atagttataa tgaacaaagg aaagataatg caaataggtt ctccaaagaa gatatatcaa
     1321 aatcctaaga atttatttgt agctcaattt atagggagtc cttgtatgaa catactagat
     1381 ataaaaaatg atattaaatt tggattcaga ccagaaaaag caacactaga gagtataaac
     1441 atagatggaa aaaatgatga tgtatttagc ctatttggaa aagttgtgac taaagaagtg
     1501 ttgggaaatg aaactatata ttgtttatct gttcttaata gagaaataag agtcaaaacg
     1561 gaaaatgata tatttgatat tggaagaact ttaagaataa gtgtattaga aaaagattta
     1621 tattattttg ataaaaatgg agaaagaata gaagatgtaa aagtatgtaa aagtatgtat
     1681 tctaaaatta aaggagatat ttatgaaaaa gcaatttaat aaagcatatt tatatataac
     1741 acctgctatt ataggaactt tattgtttat agtctatcca ataattaaga cgatatctct
     1801 aagcttcaaa tctggtagtc ttcttagttc aacctttgaa aatgtaggct taaacaatta
     1861 tacagaactt ttaaagaatc cagagtttat acaaactata acgaacactg caatttatac
     1921 tttttttatg gtgactatat ctatatcact agccatagta cttgctgttt ggctaaataa
     1981 aaattctata atacacaatt taacgcaaag tataatcttt acaccacatg taatttcact
     2041 agtatctgta gctgtattgt ggctttggat tatggagcca caatatggct ttttaaactg
     2101 gatactatcg acattacatt taccaacatc aaagtggctt tcaagtgaaa gttcagcttt
     2161 aatgtcacta attctaatag gaatatggaa gactcttgga tacaatatct taatagtatt
     2221 atcaggtctt aaatccatac caaactatat atatgaagca tctaaattag ataatgcaaa
     2281 caaaataacg aatttcttta aagtgacatt gccgctatta tcaccaacaa tattttttct
     2341 tatgataaca acaacaactg catcttttca agtatttgat gagataagta taatgacaca
     2401 aggtgggcca gtgggttcaa ctaacatgtt atcttattat atatatgagt ctggatttat
     2461 atactatgac atagggcaag cgagtgcagc gagtatgttt ttgttagcta tagttatgat
     2521 tgctacatat gctaacttta gactcttatc aaagaaagtt cattatcaat aaagaaaaag
     2581 tagatattat aagatttatc caaaaggagg agacaatgga tattatacaa cctatcaaaa
     2641 aagacaaagt tgatataaaa aaaatagcat caaaatcaat ggaaatatta attctattac
     2701 ttttatctgc aatatttata ttccctttta tatggatgct atcgacatcc tttaaaaatc
     2761 cacaagaaat gatgcaatta ccacctacta ttataccaaa tgatatagtg ttagaaaatt
     2821 atagtacagc atggcattca ggtccatttt ttagatattt actaaacagt gtatttgtaa
     2881 caggaagtgt tttaatttta caatttttag ttatggttcc agcagcatat gcattttcta
     2941 agattaaatt taaaggtgaa aaaatgttat ttgggctttt gcttgtagga cttatgattc
     3001 caccacaagt aacttttcta ccagtctata tgatgatgag taagtttgga tttataaata
     3061 cttatattcc acttataatt ccatttatga catcttcatt tgggatattt ctgcttagac
     3121 agaattttat gcagatttca gatgaaacta ttgaagcagc taaactagat aatgcttctg
     3181 acttaaaaat aatgtttaga ataatggttc ctatggcaaa accagcagta ataacattta
     3241 tattatttaa ttttatatac cattggaata attatttctg gcccttagta atgacaaata
     3301 cagatgcaat aagaacttta ccaataggag ttgcgctcct taaatcttca gaaggaatta
     3361 ctgcatggaa tgtaataatg gcaggaaata taattctaat tttaccaata attcttgttt
     3421 atatatttgc gaataaaaaa gtaaaagaag cttttatgta ttcaggaata aaataaaaaa
     3481 ttaaagacta aatttggagg atgaaaatga agcttaaaag aaaattagca acaggattag
     3541 caataacatt attattaggt tctttagttg ggtgttcaaa ttctaatgat gcaaatgcat
     3601 ctaaaggaga aaagactgat agcaatatta cgaagataga tttctgggct cctttaggtg
     3661 gaactaatgg agaaactgct caaaaaatgg ttgaccaatt taatagtgaa cataaggatg
     3721 tacaagtaaa tatgttaaaa cagaaagatt actatgaaaa tgcaacaaaa ctacaggcag
     3781 ccttaacatc taaagaccaa ccagatgtaa cattattaga aataactcaa acaggtacat
     3841 tcgcatcagc aggtgcttta gtagatatga gtaaatattt tgataaaaca tatcaagaaa
     3901 gattcttttc tggtctttta acaaattcat attatgagga taagtttgtt ggtatgccat
     3961 ttaatagaag tacaccaata ttatacataa atagagatat ggcaactaaa gcaggtcttg
     4021 acccttcagg tccaaaatca tgggaagagc ttaaggatta cgctagtaaa atgacaaata
     4081 aatcagaaga tacttatggt tttgaaacac caatagatat ttggttctat gaagctatgg
     4141 taatgcaaag tggaggagaa ataactaatg gtaaaaaagt agcatttaat aatgaggcag
     4201 gacaagcacc agttaaattc tggcaagata tgatgaaagc tggaataatg aaaatgcctc
     4261 ctggagaaga ttataatgcc tgggacgtag caaaacaaga ttttgtaaat ggtaaagtag
     4321 gtatgatatt tacatcaaca gcagatttag caggacttat gcaacaaaca gaaggtaagt
     4381 ttgaaatatc aacagcattc ctaccaaaaa atcaaaaata cgcaactcct acaggtggag
     4441 ctaatctagt tatgcttgaa ggtggaacag ataaagaaaa agaagcaagt gcagaattta
     4501 tagaatggat gacacaaaca gataaaatcg ttcagtttag ttcatcaaca ggatacttac
     4561 caacaactga agatgcaaca aactcagaaa agttacaaac attatataaa gaaaaacctc
     4621 aatataaggt tgcaactgac caattacaat atgctgttgc acttccaatg ttaaatggat
     4681 acaaggaagc aactgataag ctaatggatg agattaaaaa ggggcttact gatttaaatg
     4741 caaatccaaa agatgtagta agcaaaggaa cttctgcaat gcaagcagta atagataaaa
     4801 caaataaata attatataga cttgtaagtt gattaaaagt attcaataat atataaatga
     4861 agaggtaatg taaatgacaa aggttatagt attatcagta gattctttat ttgaaaaaga
     4921 cttggaattt gtaaaaaatc taccaaactt taaatctata ctagaaaatt gctccatagt
     4981 aaaaaatata aattgtgttt atcccactct gacatatccg tgtcatacta gtatggttac
     5041 aggagtatat cctaaaaaac atggtatata tcataatgaa aaatttgacc caaataaaga
     5101 aaataaagac tggtactggt attcaaagga cataaaagta aaaactatta tagatgtagc
     5161 aaaagaaaat aatctaacta cctctagtgt attatggcct gtaatgggag caaatccaaa
     5221 tatagattat aatattgcag aaatatgggc tcctagtaga gaagatgacc caagagaaac
     5281 ttttgaacga agctccagta aggttataat ggacggtatt tacaatagac attgtcatta
     5341 tattgattgg aaattagaac ccaacatgga tttatttgga gtaaactgtt cagtagatat
     5401 aataaaggaa tataaaccag atttaatgct aatacattta gctacattgg accatacacg
     5461 acataattat ggcttattta atgacgaagt agataaagca ttaaaaatga atgataaatg
     5521 gctaggagat attattcagg ctacaaagga tgcaggtaca tacaaagata caaattttat
     5581 aatacttggg gaccatggtc atcttagagt tgataaagtt ataaatccaa atgtcttgct
     5641 taaatcaaat ggatttataa aagttgaaaa tggagaagtt aaggattttg atgcctatgt
     5701 aaattcttct ggaatatcag ctcaaataat agtaaataac ttagataggt taacagaatt
     5761 aagagaactg cttgaagaat ttaaagaaga attattcata gagaatattt ttaccaaaga
     5821 ggaagcatct aaccttggtc ttgaaggtga ttttgaaatg gtgattgaag gtcttgaagg
     5881 aatttcattt ggaaatgatt tcgaaggaag tattataaaa gattcagata taaaagatta
     5941 caagtttgct gttgcgacac atggtcattt acctactaaa ggtaatagac ctccatttat
     6001 agcttttgga ccaaatatta aaggtggtgt ggttatagaa gaaggagacc tgagagcaca
     6061 tgcagcaact atattaaaaa tgtttgattt aaaattagat ggagttgaaa aagaagcatt
     6121 tgattttatt atgtaagttg aataaagtat ttattttcca tgaattatag acttctattg
     6181 caaagataga agtctttttt tatgttttag atttaagtaa aatttaaatg ggtaaaatat
     6241 ttaaaataac ttaaacaatt ttataaaggt atgatataat aatacatgtc aggaactaat
     6301 gttcgaaaaa aggagtgata ctatggattt taaaataaaa tcagacttca aacctacagg
     6361 tgaccaacca gaagctatta aatcaatagt ggattctata aatagaaatg agaaattttc
     6421 gacattatta ggtgtaacgg gttcaggaaa aacattcaca atggcaaata tcattcaaca
     6481 agttaagaaa cctaccctaa taatggctca taataaaact ctagcagcac aactttacag
     6541 tgagtttaaa gaatttttcc cagacaatgc agttgaatac tttgtaagtt actatgatta
     6601 ttatcaacca gaagcatatg tagctcacag tgacacttat atagaaaaag atgcaagcat
     6661 aaatgatgaa atagataaac ttcgacattc tgctacagca tctattttag agagaagaga
     6721 tactataata atatcatctg tatcttgtat atatggactt ggtgacccaa aagactataa
     6781 agaacttatg ttatctataa gaccaggtat gcaaagagac agagatgatg taataaaaag
     6841 gttaatagag atacaatacg aaagaaatga cataaacttt acacgaggta cctttagagt
     6901 tagaggagat atactagaaa tattcccagc tagtaatgat gaaaaagcaa taagaataga
     6961 attttttggt gatgaggtag atagaataac agaaattgat tatgtaacag ggaagattgt
     7021 tggtactaga aatcatgttg ttatattccc agcatctcac tatgtaacaa cgccagaaag
     7081 aattgaaaag gcaattgtag aaatagaaaa cgagcttcaa gaacaaatta aatttttcaa
     7141 ggaaaatgat aggctattag aagcacaaag aattgaacaa agaactaagt atgatataga
     7201 aatgttaaag gaaataggat tttgtcaggg gatagagaac tattctagac atattacagg
     7261 aaggtcagaa ggagaaagac catatacttt aatggatttc ttcccagatg attatttgat
     7321 aattgtagat gaggcacatg tcactatacc acaagtaaga ggtatgtatg caggagacag
     7381 gtctagaaaa acatcactta tagagaatgg ttttagatta ccttctgcac ttgacaatag
     7441 accattaaat tttcaagaat ttgaaggaaa tataaatcaa atgttgtttg taagtgctac
     7501 accaggacct tatgaaattc aacactcaga gacaatagca gaacagataa taagaccaac
     7561 tggcctttta gacccaattg tagaagtaag acctataaat aatcaaatag atgatttggt
     7621 aggagaaata actaaaacta tagaaaaaaa tgaaagagtg cttataacca ctttaactaa
     7681 aaaaatgagt gaggacttga ctaactatct taaagaaata gggataaaag ttaaatattt
     7741 acactcagat atagttacat tagaaagaac agaaataata agagatttaa gattagggaa
     7801 gtttgatgtc cttgtaggaa taaacttact tagagaagga ttggatatac cagaagtttc
     7861 acttatagca attttagatg cagacaaaga aggtttctta cgttccgaaa cagctttaat
     7921 acagactatt ggacgtgcag ctagaaatga aaatggaaga gtaattatgt atgcagacag
     7981 gataactgac tcaatgcaaa atgctattga tgaaacaaag agaagaagag atatacaaaa
     8041 tttatataat gaagagcaca atataattcc taaaactata cagaaaaata taagagatag
     8101 tatagaagct actaaggttg cagaggaaga agttgtatat ggaatatctg atacagatga
     8161 taaagacgaa ataagagcta atatagataa attaaaatca gagatgatgg aagctgctca
     8221 aaacttacaa tttgaaagag cagcagaact tagagataaa gtgaaacaat tagaagaaaa
     8281 attggaaaaa tagaaaggta aaaacaacat tatggaagat aaaattataa taagaggagc
     8341 aaaagaacat aatttaaaaa atatagattt agaattacca agagataaat ttattgtttt
     8401 tacaggtttg tcagggtctg ggaagtcttc tttggcattt gatacaatat atgcagaagg
     8461 gcagagaaga tatgtagaaa gtctatctgc ttatgcaaga caatttttag gtcagatgga
     8521 aaagccaaat gtagaatata tagagggttt atcaccagct atctcaattg accagaagac
     8581 tacctcaaaa aacccacgtt ctacggttgg aacagtaaca gaaatatatg attatttgag
     8641 actattattt gcaagagtag gagatgtgta ttgccctaca tgtggtgaaa aaataagtca
     8701 gatgactatt caagaaatag ttgataaaat gctagatttt ccagatagaa cgaaattaca
     8761 aattctttca ccaattgtta gaggacaaaa aggtacacat aaaaaagtct ttgataatat
     8821 caaaaaagaa ggatttgtaa gagttagagt taatggtgag aactatgaag ttagtgatga
     8881 tataatctta aataaaaatc aaaaacataa tatagaagtt gtagtggaca gaatagtaat
     8941 taaagatgga atagaatcaa gactagcaga ttcaattgaa actgcagtta agctatctga
     9001 tggtcttgta atagcccaaa taatagatgg agaagaaatt cttttttcaa ctaaatttgc
     9061 atgcccagaa catggaattg gcatagaaga attatctcca aggatgtttt catttaatgc
     9121 tccctttggt gcttgtgatg tttgtaatgg tcttggggaa agtaaagaag ttgacccaga
     9181 attagtagta ccaaacaaag atttatcaat aaaacaaggt gcagtggcag catggggttc
     9241 aacaggtgtt aatgatgaca cttattacag taaaatgata aaaagtttag cagagcattt
     9301 taatgtatct ttgacaacac cgtttaaaga tttaccagat gattttgtgg aggaattact
     9361 ttatggtaaa gataatataa ttgtagagtt tacttatgag tcaaaatttg gaggaactag
     9421 aaattataaa tcatactttg aaggtgtaat agtaaactta gagagaagat atagagaaac
     9481 taattcagat tacatgagag ataagattga agaatacatg gcagagagac catgtccaaa
     9541 gtgtaaaggg atgagactta aaaaggaagt tttatctgtt ttagttgatg gaaaaaatat
     9601 aatggaagtt acaaacttat ctgtaaatga attgattgac tttatggaaa atataaatct
     9661 tacagaaaaa cagagattta tagctcatga gattataaaa gagataaaag gaagagctat
     9721 gttcttaaga gatgtaggtc ttgattattt aaatttatca agaaaagctg gaactttatc
     9781 aggaggagaa gcgcaacgta taagattagc tactcaaata ggttctgcat tggttggagt
     9841 tttatatgta cttgatgagc caagtatagg gcttcaccaa agagataatg ataggcttat
     9901 aactactctt agacatctaa cagatttagg aaatacctta atcgttgtag agcatgatga
     9961 agacacaatg agagaagctg attatgttat agacattggt ccaggtgcag gtatacatgg
    10021 tggtgaaata gttgcacagg gtactttaga tgaaataatt gaaaatgaga actcaataac
    10081 gggtcaatat ttaagtggta aaaaacaaat attgcttcct gagactacta gagaaggaaa
    10141 tggaagtttt atagaaatag ttaaagcatc agaaaataat ctgaaaaata ttgatgtaaa
    10201 gttcccatta ggtaagttta catgcataac aggtgtttca ggttctggaa aaagtacatt
    10261 aataaacgat atactttaca aaggtgttgc aagtaaagtg aatagactta agcaaagagc
    10321 tggtaagcat aaggagataa aaggaattga aagtatagat aaagttataa atatagacca
    10381 aagtcctatt ggaagaacac ctcgttcaaa tcctgctact tatacaggtg tatttgattt
    10441 tataagagat atttttgcat ctactaatga agctaaagca agaggttata aaaaaggtag
    10501 atttagtttt aatgtaaaag gtggtagatg tgaagcttgt aagggtgatg gaataataaa
    10561 aatagaaatg catttcttac cagatgtata tgttccttgt gaaatttgta aaggtgaaag
    10621 atacaataga gaaacattgc aagtaaaata caaagataaa actatatctg atatattaga
    10681 tatgaatgtg gaagaagctg ttgagttttt cgaaaatata ccaaatataa aaagaaaatt
    10741 agaaacttta atggatgtag gactttcata tattaaatta ggacagcctt caactcaatt
    10801 atcaggagga gaagcgcaac gtataaaatt agctgctgaa cttagtaaaa gaccaacagg
    10861 aaagactttg tatatattag atgaacctac tactggactt catatggcag atgtagacaa
    10921 gctaatccaa gtattacaaa gactagcaga tacaggaaat acaattatag tcatagaaca
    10981 taatttagat gttataaaga cttgtgatta tgtaatagac ttaggaccag aaggcggaga
    11041 taagggtgga actatagttg caactggaac accaaaagaa gtatctaaag ttgatggttc
    11101 ttatacaggt caattcttaa agaaatattt ttcttaagtt atataaattg tgaaaaattt
    11161 tagagcagat atacgataaa ctgttttgtt ataagtaaat tagtcaaata taagttgtaa
    11221 atagtaatac aaagtaaagt ccatattact cttcatggtt aaaattgttt tcaaatcaat
    11281 tatagaaggg aatatggact ttaacttgtc taaagcactg gaaattgtat aactttttaa
    11341 aattcatatt ttagggtata attttagtat aaaatttaat gttttggagg gcgagatgtt
    11401 tgatatacaa gagcatttaa aaaaattacc ttctgagccc ggagtatatt taatgaaaga
    11461 caaatacgac catataatat atgtgggaaa agccatatct ctaaaaaata gggtaaggca
    11521 gtattttcaa tcttcaaaaa accatacatc taaagtaaaa tctatggtta agaatatata
    11581 taagtttgag tatattataa cggattcaga gttagaggca ttaatacttg aatgtaattt
    11641 aataaaaaga tacagaccaa agtataatgt agtgcttaga gatgataaaa cttatccata
    11701 tataaaagta actacgaatg aagattatcc aagaatctta aaagttagaa gagttcttaa
    11761 agataaggca aagtattttg gaccctatac caatataact gctgtgaatg ataccttgga
    11821 gcttataagt agtacgtatc caataagaag ctgtaaaata gatatagata aagcaataaa
    11881 gaataagaca agaccttgtt taaatctaca cataaataaa tgtttaggac cttgtacagg
    11941 aaatgtttct aaagaagagt atggaaaaat gatagaagag attataatgt gtttatctgg
    12001 taaagaagaa aaattgatgg aacttttaaa ggaaaaaatg aatgagagtt ctatgaactt
    12061 tagatttgaa gaggctgctg tatataggga taagataaag agccttgaag agatgataca
    12121 gaaacaaaaa atagatgcta ctgtaagtga cttaaaccaa gatgtggttg caatggcaag
    12181 agctcataat gaagcttgtg tccaggtatt ttttataaga aatggtaaga ttgtaggtag
    12241 ggaacatttt atattagaag gtgtaatgga tagtccaaga gcttctatat taagttcatt
    12301 tgtaaaacaa ttttataatg aacaagagta tatacctaaa gaattaatta tagaagatga
    12361 gatagaagat agttctatat tagaagaatg gctgtcatct aaaaaggggc aaaaagtaac
    12421 aataagagtt cctcaaaagg gagagaagaa aagcttagtt gaaatggtta ggaaaaatgc
    12481 tgtagaatat cttgaaaaat tttctgatat gaataaaaga aaatatgaaa aaagtattgg
    12541 agcattggaa gaattaaaac aaatattaaa tctagaaaag ttgccaataa gaatagaggc
    12601 ttatgatata tcaaatatac aaggtgtaga ttcgattggt tctatggtag tgtatacgaa
    12661 tgctaaaaaa gataagaagg aatataggag atataaaata aagacagtta ttggacctaa
    12721 tgattatgat tctatggctg aaattgtaga tagaagatta aaacatggaa atttacctga
    12781 cttgatattg ttggatggtg gaaaaggaca agttagtgca gtaaaaaaag tactagaact
    12841 caatgatgta gatatacctc tttggggaat gtacaaagat gataagcata gaactaaagg
    12901 attgatatgc aaagaaaaag aaatagaact agataaaaca actaatttat atagatttat
    12961 tgctagtata caagaagaag ttcataatta tgcaataaca tatcatagaa gtctaagaaa
    13021 taaagctttg acaaaatcta tcttagatga tatacaagga ataggtgaaa aaagaaagaa
    13081 atcattatta aatcacttta aagatgtaga ggctataaaa aaagctacta tggaagaact
    13141 tttagaagta gatggaatga ataaaagcat tgcagataat gtttataatt tttttagaaa
    13201 ggaagaaaat taatggaaac tagcaataaa gtatcaataa gagagataat aaaagagttg
    13261 aagttaaaag tagtatacat gcctgatgat gtagattatt atgtctactc tcaagatata
    13321 aatagaccag gattacagtt tgcaggatat tttgattatt ttgcatatga aagaatacaa
    13381 atagttggaa agacagaata taattttttt ggattaatgg atagtcatat tcgagaagaa
    13441 gtactagata gatttttctc atatgaaata ccagcgttaa taatttctag agacttggaa
    13501 atcaagccag atgtaattga aaaggctaaa aaatataaaa gaatactttt gagcacaaat
    13561 agaaatacca ctagacttat aaatagactg tcaaactatt tggataataa gttagcacca
    13621 cacacaacaa ttcacggggt gctagtagat atttatggta taggtgtact gataaaaggt
    13681 gaaagtagta taggaaagtc ggaaacagca ttagaactga ttcaaagggg taatagatta
    13741 gttgcagatg atgctgtaga aataagaaaa ttagatgaaa gtatgcttgt gggtcagtca
    13801 cctgaactaa taagacattt tcttgagata agaggaatag gaataataga tgttagaagt
    13861 ttatatggag taggggcaat caaaaattct aaaatgatag atttagtagt tcatttagaa
    13921 gcttgggatg aaactaagta ttatgataga ctaggactgg ataaagaata cgaagaaata
    13981 cttggtgtta atgtagagaa attagttgta cctgttaaac ctggaagaaa tactgctatg
    14041 atattagaag tagcagcaat gaattttaga caaagaggaa tgggatacga tgcagctcaa
    14101 gaatttacta aaaaattatc aaaattaatc gatactaagt agtactgaat aatagtgaac
    14161 tacacatcat ttaattaaat attgattagg attatgtcct acaccttata aattaaaatc
    14221 aagttgtata tatataatgt ttattaataa gatatattat ataaggataa tttaaagtac
    14281 agtgttagat tataataata ctagattaat tttatatttg agtttcatta tataacaaga
    14341 aagttggaat tttttatggg aatagaatat tttagtaaac ttttagaaag tagtactgaa
    14401 aaagaattgc tcttaagtaa aaagtcaaat aacataagta cagcaagatt aatatctttt
    14461 ttgatagtga tagcagggtt tgctattgga ttttacaata aaaatatagt aggtattttt
    14521 gttggagttt tatcaataat aatatttata gcactcttag ttattcatag taaagtaaaa
    14581 gaagaagaaa catattttaa aagtaagagc gaagtattaa ataagtatat taagagattt
    14641 ggagatggtt ggaaggaatt taaaatagat ggtaaagaat acttaaaaga tgaaaattcg
    14701 caagcaaaag atttagactt atttggaaga gcatcattgt atcaatatat ctgtgtagct
    14761 aatacatctt atgggaaaaa ttttttagcc aaatatttgt ggaatgaaaa tccagatgag
    14821 aatgtaatct tagaaagaca gagggctata aaagaacttt tatcaaaaga tgatttttct
    14881 attcatattc aaatactcag taatataatt ggtaaagagc aaaaaaataa ttcagatagt
    14941 agtatagaat cgtttataga gtatggagaa aataagaatg tgtatatacc aaaatggatg
    15001 catattttta cttggggtct accaactgca acaatcttat cttttatatt ttgtatgtta
    15061 ggatttttac ctgttttacc tgttttttta ctttttataa tccagttagg gtttagtggt
    15121 tttggatatc caagacttat gcaaactctt tctccattat tttcatttag tagaagtata
    15181 caagtatatg aaaaaatgtt tgaggtttta gaaaaagaga cgtttgagag tgcatatttg
    15241 aaagaattac aagataaact ttctaaggga agtggagttt caagaggtgt taaacaatta
    15301 aattcaatag gaaatgctgt aaacctaagg tataatcaga tactatatat aattgcctgt
    15361 ggtgttttga tgtggaacta tcattgtgca gaagctttgg agcgatggaa aggtatatat
    15421 ggaaatcaaa ttagagattg gtttgaatct attggagaat ttgaagctct aataagttta
    15481 acagttattt ctcatgtaaa ggaaaataca tgttttccag taataaaata tgaagatact
    15541 ccaagattga aagttgaaga ggtataccac ccattaatag cagaaaaaag tgtcatagca
    15601 aattcgatac aattaaattc tcagacttgt attatcacag gttcaaatat gtctggaaag
    15661 acaacatttt taagaagtat cggtgtaaac ttagtgctgg catatgcagg tgctccagta
    15721 tgcgctaaga gttttgatgc gacctgtatg gctatattta cttctatgag aatacaagat
    15781 gatgtaagtc aaggaatatc aactttctat gctgagattc ttagaataaa atcaatgatt
    15841 caatatagtt taaaagaact gccaatgttg gttctagtag atgaaatttt taagggaact
    15901 aactctgctg atagaattat tggagcaagt gaggcagtaa agaaattatc aaaaccctgg
    15961 gttataagta tggtgacaac acatgacttt gagctatgtg acctttcagg tagtggagat
    16021 gttgaagttg taaactatca tttctcagag tactatgtag acgataaaat tcattttgac
    16081 tataagataa aagatggaag atgtaaaact acaaatgcaa aacaacttat gagaatggca
    16141 ggtattcttt aattaataga taggttaatt aaagaataag tctatttaga aatataattt
    16201 aatttgtgaa attaataagg attgtcttaa attacgtaaa agtattttaa gacaatcctt
    16261 ttttaagaat aaattttata ctttgttatg actacttagc ttcttcacaa gcacattctt
    16321 gtggacactc tccatagaca caactcttat caaagtaatg agtatgaagg tatttatggg
    16381 ctacatcact atttggttct ccaaagaagt ctttataaat agcttgtaaa tcaggattct
    16441 catgagattt acgaatagcc ttatttctat ctatttcata taacgcattt gcacgtctat
    16501 caactatttc agtattacca tggtgataag gttgaccagc acctccaaca catccaccag
    16561 gacatgccat aacttctatg atatggtatt tacattctcc acttctgacc ttatccataa
    16621 tctttctagc atttttaagt gtatttacaa tacacacatt aactgtagtt ccatcaacat
    16681 ctatacttgc ttccctaatt cctttaagac ctctaacatt agtgaagttt acattatcta
    16741 aagtcttatt agttatcttc tcatatgaag tacgtagggc agcttctaaa actccaccac
    16801 ttgctccaaa tatagatgca gcacctgtag attttcctag aggattatca aaatcttggt
    16861 cttgaagatt aggtaaatcg atagcagctt cttttatcat tttagctaac tctctagtag
    16921 ttatagaaag gtcaacatct agtattccag attcacttaa ttcttctctt gaagcttcat
    16981 attttttagc cacacaaggc attacagata caacataaag ttcttcagga ttgattccta
    17041 atattttagg tgcatagtag tttttagcta tagaaccaaa cataccttga ggagacttac
    17101 agctagatgc taagtttaac ttgtctggat aattgtgttc taagaagttt acccatgcag
    17161 gacaacaact tgttaatata ggaagatttt cacctttttg gattctttct ataaattcag
    17221 tagcttcttc cattatagta aaatctgcac caaagtttgt atcaaataca tgttcaaatc
    17281 caagtgcttt taaagcagct accatttttc ctgtagagat tgaccctggt tctaatccaa
    17341 actcttcacc aatagcaact cttacagcag gagcaacttg cactactata gtcttttctt
    17401 ttttatttaa aacatcccaa agtttaggta cattatctac ttctgttaat gctccagttg
    17461 gacagacaga tatacattga ccacagaatg tacactctgt ttcaaccata tcagagttaa
    17521 agaatgtact aactaaagta ttaaatccac gattaactcc agataatgct cctactgttt
    17581 gtatgtcatt acatacagtc tcacatcttc tacataatat acacttagaa tggtctttaa
    17641 ctaaagattt agtagaagta tctttacctg caaaagattt ggaaccttga tatcttattt
    17701 ttcttactcc taaatcagca gctatagtct gtaattcaca atctccattt ttttcacaga
    17761 caaaacaatc ttgtggatgg tctgataaca ataattcaac aatagttcta cgagcattta
    17821 atgctttagc actattagtc tgaactttca taccttcctt tataactgtt ccacaagctg
    17881 gaactaagcc tctctctgtc tcaaccatac aaatacgaca agaagcacaa gtgtcaagct
    17941 tatctatttc gttcatatgt aaatgacaaa ggttgtgtat ttttatattt attaatttcg
    18001 cagcatctaa gatagaagtt ccactaggtg ctgaaacgtg tttgccatta atagttaaat
    18061 taactaaact cattgttatt cctcctccaa ataagttatt tcttgattat agcgttaaat
    18121 gtacaattat ctatacaagc accacatttt agacacttag aagtatctat tgtatgttgt
    18181 tccttaacag aacctgttat acaaccagca ggacacactc tagaacattt tgtacaaccc
    18241 ttacagtcat ctgttataaa gtaagaaagt aagttctgac atttaccagc aggacatttc
    18301 ttatctacaa catgagctat atactcatct ttgaaatatt gaagagtact taaaacaggg
    18361 tttggagcag ctttaccaag accacataat gaagcagttt gtatagtttc agcaaggttt
    18421 tctaggtcat ctaaatcttg tagagtacca ttaccttctg taattttagt taatatttct
    18481 aataatcttg tagtacctat acgacaaggt gtacatttac cacaagattc ttcaacagta
    18541 aactcaagga agaacttggc tatatctacc atacagtcag attcatcaag aacaagcata
    18601 ccaccagagc ccatcattga accgatagaa cttaatgaac caaagtctat aggagtgtct
    18661 aaatgttcag ttggtataca tccaccagat ggtccacctg tttgaacagc cttaaatttc
    18721 ttaccttcag ggattccccc accaatttca aatacaatat ctcttaaagt agtacccatt
    18781 ggaacttcaa caagtcctac attttctact tttccaccaa gagcaaagac tttagtacca
    18841 ctagaatctt cagtacctaa gttggcaaac caatctccac ccttaagtat aattgcaggt
    18901 atgttagcaa aagtctcaac gttatttaag caagtaggag atttccatag accactctta
    18961 gaagaactat aagttttcat tctaggttca ccacgtctac cttcaattga atgcattagc
    19021 gctgtacctt caccacaaac gaaagcacct gcaccatatt ttaattctaa tttaaagtta
    19081 aatccagtgc ctaagatatt ttcgccaagt aaaccgtatt tttcagcttg agctatggct
    19141 acttttaatc tttctataga ttttggatat tctgctctta tgtatatgta tcctgtatca
    19201 gaacctatag cgtatccaca tattgccata gcttctagta cactatgagg gtcaccttca
    19261 agtacagatc gatccataaa tgcacctggg tcaccttcat cagcattaca tacaacaaac
    19321 tttttatctg ttggaccagc tggatttttt gaagcagctt cccatttaga gccagtaggg
    19381 aaacctgcac cacctctacc acgaaggcca gaagttttta cctctgcaat aacttcttga
    19441 ggagtaagag aagttaaaca tttgcctaga gctaaataac catcattggc aatatattct
    19501 tctatactat ctgggtctat aagaccacaa ttttttaaag ctatacgtaa ctgttttttg
    19561 tagaaagaca tttcttcttg ttcttcaact tttttactta aagattcttc ctcatataat
    19621 aattcctcga caactgtatt tctaattaag tggctttgaa ctatcttttc agcatcagat
    19681 ggctcaactt ttacgtagaa aacgttatca ggataaactt ttacaatagg accttgagca
    19741 cagaaaccaa aacaacctgt caaacgaaca ctaactttat cttggattcc tgatttcttt
    19801 atttcatttt ctaattcact aactatttct agactgtttg aagaggtaca tccagtatca
    19861 caacaaacaa gtaattctct tcttaataca ttttccttag aataattttt tcttaagcta
    19921 agattaggtt tcagctcatc agctaaaact tttaattcat caaatgaatt tactttacgc
    19981 attatttatt cacccctctt aacaattcaa ttctaattct ctataagtat ctaatatttc
    20041 gcttacttgg tcaggtttca ctttaccata aactttacca tttacagtaa caactggagc
    20101 taaaccacat gcccccaaac atcttaaacc ctctaaagaa aatttaaaat cactagtagt
    20161 ttctccaact tttatgccaa gctgtttttc aaaagcactt aagattttgt cagcaccttt
    20221 tacaaaacat acagttccta gacagacact gattttatac ttacctacag gttctgtagt
    20281 aaaataagaa tagaatgtaa caaccccata tacctttgca ggagctactc caagttttct
    20341 agcaacatga agttgaactt cttttggaag atatccaaat ataccttggg cttcatgtag
    20401 aacttgtatt aacgcacctt cctttgttgt aagagagtca ataaatatat ctagttcgtc
    20461 aaataattgc ttgttgtgtg aaataaaatc gcacataaca aatccccctt ttctttttaa
    20521 agttattatt tttcataaaa taattaacca tgagttgacc ccaacattat gtgggtgaac
    20581 aaaaccagaa caataaagaa agaataatat acaacaattt ctttatttat aaaaacaatg
    20641 caaaaaagtt acctattaaa aataaaaact atactagtct attataatat aaaataattc
    20701 agaatagtta aaaaaaataa aaaaaatgag ctaaattcaa taaaaaaaaa ataatacata
    20761 taaaaaactt taaaaaataa accaaaatgt aaaattttta taaaataaaa gatttataaa
    20821 actgctgata atagtcttga aattgattcc ttgattttta tataagtaga cctagaatta
    20881 tatatatcta atgttatttc cttagaattt aaaatatcat tttcaaatat aattctttgt
    20941 tccaatgctt tttttgaaga gtacataaat gcattaactt cgaaattaag ctcaaaactt
    21001 ctgatatcca tattagctgt tcctatagag catatagagt catctataac tattgtctta
    21061 gcatgtaaaa atgcattttg accataagtg tagattttag ctccaaactt taaaagttct
    21121 ccagcatatg aatatgatgc ccagtataca aagggatggt caggtttaga aggaatcata
    21181 actctcacat caacaccaga taaacaagct atttttaaag tatctataaa agttgagtca
    21241 agtattaaat aaggactctg tatgtatata tactttctag ctttctgaat cattttaagg
    21301 taaccatatt taatctcatc aagttctgat atatctggac cacttgatac tatctgaatc
    21361 ccaatatttt cagaaggatg attagaattt gtatcttctt ctataaagta cttttctaaa
    21421 tctaaatctt ctttagttgt atatctccaa tcaaggatga atctcatatt taggtcaatt
    21481 acgcaatcac cagtaagctt agtatgtgta tctctccata gaccaaattt tggatttcta
    21541 cctaaatatt catcaccaac attatatcca cctacaaatc ctaccttacc atcaatgaca
    21601 acaatttttc ggtgatttct atagtttaag ttaaagttta caattttcaa gaatgatggg
    21661 aagaagcttc caactttaac accactttct ttaagtctgg aaagtgtact attttttagt
    21721 gttctaccac caactgcatc aaataaaagt cttacttcaa caccttcttt agctttgtct
    21781 ataagaatgt ctattatttc agttccgatt ttgtcatctt tgaaaatgta aaattgtatg
    21841 tttatatatt ttttagcttt tttaagttct tcaagaagac tgttaaaaaa ttgactagat
    21901 tcagcataaa tccacacatc gttattattg gtataatgag cattatttga attagccaat
    21961 gcataaatca tatccttatg ttgatgtata tctgaatcaa tttcagatgt agattggagt
    22021 ttaacctgag tatctagtat attacttttg attatcttat catccttttc tttcaatcta
    22081 aacatattgt tttttgaaat atttctgcca aaagctatat aaagtatgaa tccaagagca
    22141 ggaatcaata ctaatataag aagccatgtt aaagttgtat ttatgtttct tttttctcta
    22201 aagataaggt ttagtataac catgaaatta attatatata ttgtagtaac tgctatttca
    22261 tatattgaca tttcgaaaaa tgatatatca aacataaaat tccctccttc aaatatttat
    22321 taaaataagt aattatatat aataacac
//
LOCUS       DAMJWO010000070        22112 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.071, whole genome shotgun sequence.
ACCESSION   DAMJWO010000070 DAMJWO010000000
VERSION     DAMJWO010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22112
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.071"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            579..1886
                     /locus_tag="PC366_002731"
     CDS             579..1886
                     /locus_tag="PC366_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578229.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKADIGCVEEIDNEDDNLVLDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYVDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVVTIDKRY
                     DYRKELKSELKSKSGAIITHIGRIRRKDGRIFRTNNTINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYVPTWSDTLSNYHNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYVILVEQSKILTDEAFDCNLASKNI
                     RLLLDTCKIPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRKTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     misc_binding    1972..2234
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            2360..3163
                     /locus_tag="PC366_002732"
     CDS             2360..3163
                     /locus_tag="PC366_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2578230.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPDNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGDTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINKTLKEMKKDGTFDKIYDKWFK"
     gene            3201..3812
                     /locus_tag="PC366_002733"
     CDS             3201..3812
                     /locus_tag="PC366_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF2578231.1"
                     /translation="MLQGLEIVIAMFCITLIVSIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRVIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            3844..4515
                     /locus_tag="PC366_002734"
     CDS             3844..4515
                     /locus_tag="PC366_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDF2578232.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            4814..5176
                     /locus_tag="PC366_002735"
     CDS             4814..5176
                     /locus_tag="PC366_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HDF2578233.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQNPPSKEELKS
                     IYKTSGYDIKKFFNTSGMKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLLDGKN
                     VLLGFKEDVWKSTLLKED"
     gene            5612..6313
                     /locus_tag="PC366_002736"
     CDS             5612..6313
                     /locus_tag="PC366_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HDF2578234.1"
                     /translation="MSIEDLYDFECVPLNNEIDIDVLFEKMIEDGKEKEYTPIIVIDE
                     KVGLLRKNIDMITKEYGSLENYREYCLTKYNEIDVNQFFDFRKSEISELLKELIDLED
                     DFYDYKHFRPIINIDIFHEYNKVYIAKIPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSVKNLTKDGKKFDDLCIELVFYCEDIIIQGYETLKAL
                     KDVLKRSTIVLFWWD"
     gene            6584..7402
                     /gene="larE"
                     /locus_tag="PC366_002737"
     CDS             6584..7402
                     /gene="larE"
                     /locus_tag="PC366_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HDF2578235.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVIAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGVDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNMDDLGDYRPGLKALSELGVISPLKDSSLKKEE
                     IRSLSKILGLNTFNKPSFACLASRIPYGVEITDENLRIVEKSEEYLFNLGFSQFRVRM
                     HGEIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            7457..8605
                     /locus_tag="PC366_002738"
     CDS             7457..8605
                     /locus_tag="PC366_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HDF2578236.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            8741..10129
                     /locus_tag="PC366_002739"
     CDS             8741..10129
                     /locus_tag="PC366_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578237.1"
                     /translation="MKVLKLITVVALMMLFVTGCNIKTESPEQLAKIPDYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGK
                     MKIKDSVKFENVKNLSELYTTLGNVASSVGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGSTGNNKNTYSSKSSATIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTGTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            10158..10856
                     /locus_tag="PC366_002740"
     CDS             10158..10856
                     /locus_tag="PC366_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2578238.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     ENDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            10859..12292
                     /locus_tag="PC366_002741"
     CDS             10859..12292
                     /locus_tag="PC366_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2578239.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVASQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            12314..13051
                     /gene="truA"
                     /locus_tag="PC366_002742"
     CDS             12314..13051
                     /gene="truA"
                     /locus_tag="PC366_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDF2578240.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKTVEEVDERFHS
                     RYNVKSKTYMYKIDNNKYHNPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNVIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESKDRCQSSDTAPAKGLCLWKVTY"
     misc_binding    13162..13369
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13622..14821
                     /locus_tag="PC366_002743"
     CDS             13622..14821
                     /locus_tag="PC366_002743"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HDF2578241.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWDIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEVYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYEAHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            15068..16114
                     /locus_tag="PC366_002744"
     CDS             15068..16114
                     /locus_tag="PC366_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4872 domain-containing protein"
                     /protein_id="HDF2578242.1"
                     /translation="MRKIIEIKHHSHDYECMWNGIEDLYINKTGECLPNDFFFLLSGF
                     GSFCYMKTNKADLKRMVALGDGRTKQMYKFLAPIVGFEYKHHEFKKYEQALKKAKSEI
                     DGGYPVILGALDMYYLPYYKKLYHKEHIPFHYILMVGYDDERIYLYDCGRTELLHLSY
                     DKLRESMNCNSPGLSKENTICTIRMNTSKNKYNIAREAIAIKRDMFLNPSKGFLGYKG
                     FEKFIKELPQWNTELDKDDYDKILTNMVMFFGTVPTIPNAIKGIKEPDTVQFKGGFDK
                     MSRMLNSIGEEYKNDSFIQVADIFDKTAIIIEKISNIIIDYLTQTCDDTEQLPLLFSE
                     VLEHMKTGYLILDV"
     gene            16222..17385
                     /locus_tag="PC366_002745"
     CDS             16222..17385
                     /locus_tag="PC366_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2578243.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDES
                     IKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQ
                     TLRGEGNIDFKEFDMSEYFNVLEEFKREHRNKIIKIYGSVEKYNEYIERVKSNEEKIA
                     KMAIKQYGTIEKFAQAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDL
                     SKNPSSTDLQEIAKEITDISKKDYEIFSMYTGDDNWYYMIQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNE
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC"
     gene            complement(17474..17854)
                     /locus_tag="PC366_002746"
     CDS             complement(17474..17854)
                     /locus_tag="PC366_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HDF2578244.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKDNISVLEKSIE
                     NEDWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EVESIKTYLGNIIESVKFDVNYIF"
     gene            complement(17857..18516)
                     /locus_tag="PC366_002747"
     CDS             complement(17857..18516)
                     /locus_tag="PC366_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HDF2578245.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERISIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
     gene            complement(18622..19596)
                     /locus_tag="PC366_002748"
     CDS             complement(18622..19596)
                     /locus_tag="PC366_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HDF2578246.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGAELISIGGVLVDNEFNTI
                     DNYYSLVKPKYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDITGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVEGDIKHNSLSDAVDLMNVCKCFFFNSPKNIDILEELYNKLPALKTPLYYIPYFED
                     ENFELKFDRTPEDIIIYLKQILTILNISKKEIYFKKRSVLVNNSKIINFKNLSSSFKL
                     IKLNEFEEYPDFILKLGDKKSFVESVIKINKSNRKSIKNLILKLSKKP"
     gene            complement(19636..19983)
                     /locus_tag="PC366_002749"
     CDS             complement(19636..19983)
                     /locus_tag="PC366_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578247.1"
                     /translation="MLNLKEIREEIIKKYIGDSLISELTEELKNILITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILIDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRVIISIDSYDA"
     gene            complement(20201..21157)
                     /locus_tag="PC366_002750"
     CDS             complement(20201..21157)
                     /locus_tag="PC366_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HDF2578248.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRVKEGNPVC
                     ESGIFEILDVTDKNRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EIAKELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTIYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIQAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPVRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            21598..21966
                     /locus_tag="PC366_002751"
     CDS             21598..21966
                     /locus_tag="PC366_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HDF2578249.1"
                     /translation="MTRPSIYHSQGYTCAEALIKSYNEEHNTDIPISIGSGMGVGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELLNKVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
BASE COUNT         8766 a         2233 c         3649 g         7464 t
ORIGIN      
        1 taataaaaca acaatggtgc taatttatat gtataaatta attatgaaaa atttatataa
       61 gtaaaatata ttaacataaa ggtaaaattt tgtatactaa aagggaatat ttacagttta
      121 atggcagttt taaaataata aattaaagct gtcattttta tttaaaaatt tttagaaaaa
      181 gtacaatagt gttaatgtgt gaattagata aggtgtatat aataatttag atgatatgat
      241 ataaaatatg ttgtaaatta aatgttttct ttgacaatat atacacaagg atgataatat
      301 ctatatgaat aaaagatagt gtgtaatttg ataatatgta attataacat tatgatataa
      361 ttacaataaa gtatgtaata atctgtagaa atttcaagct agttatctaa gttttcggat
      421 aactaaatct aaacggaata cataatgtat taaataaatg atgatactaa aatgatacta
      481 tttttataga aatttattga ggtatataat tgatgaaaat aatatattaa attatataat
      541 atattgagtt ttacataaaa gcgaaggtgg gaataaaaat gaaagaaatt gctgatgcta
      601 taacatcaga gtatttaagc tatggtatca atgaagatat tagtatctat gaaggtagat
      661 tttgcatata tttagataaa aaatatagat gtaatgggaa aatttattat aaaatgacac
      721 ctccaatatc tataagtttt aaagcagaca taggttgtgt tgaagagata gacaatgaag
      781 atgacaattt agttttggat tatgataatg ctattcttga agttcatgga tacaaaatta
      841 tttctataac aataaatact ttaagtgaat ttagtgtaga aggttatatc aatgatgact
      901 gcataaaatc taagaactcc tatgttgaat atgtagattt taatataata aacttagata
      961 aaatacctgg aaaactaatt aaatacaatg ataaggtata cgcaggtaga attgaatttg
     1021 atataaatga ttatgttgta actatagaca agcgatatga ttatagaaaa gaattaaaat
     1081 cagaattaaa gtctaaatct ggagcaataa taactcatat aggtaggatt agaagaaaag
     1141 atggtagaat ttttagaaca aataatacaa taaatctttt agatagaata tcaacagctt
     1201 tgagttttat gtgtggaaga tatgtagggt tttgtttggc caaagggtat agaagtggta
     1261 atgaagttta tagaatatgg aatgaaaatc aaatatctcc ttttagatat gtaccaacat
     1321 ggtcagatac actttcaaat tatcataata tggaaaaata tataagcctt atgtgtaaaa
     1381 agctagaaga tttttattat ggttctgcta taaagagtgt tgttgattgg tacatagaat
     1441 ctcttggaag tgctaccatg gaaaacaata taatatctgt acaaattgca cttgaaactt
     1501 tgtcatatgt aattctagtg gaacaaagta agatacttac agatgaagca tttgactgta
     1561 atttggcatc taaaaatata agactcttac ttgatacatg taagatacca tatggtaaac
     1621 atgaattaaa tatatttgat aatataataa aaaataaatt tgatgatgga gtggatttag
     1681 ttatttattt aagaaatagc atagttcatc caagtagaaa gactcataga gctgtgttag
     1741 aggttgaaga tatttggaat ataatttcaa taggaacgag atatattgaa cttgttttac
     1801 tctttatttt aggttataga ggagaatatt caaacagatt agtagaaagg tgttatggtg
     1861 aagtggaagt tgtaccttgg aactagattt ttatatttat tttaaaatat atattgacat
     1921 atattgcctt atgctataaa atcaatatca taataataat tcagaataac attaaatgct
     1981 aagaaaagaa atagtaaagg tagttaatct taaacagaga gtttccgatt ggtgagagga
     2041 gcaatagatt ttactttgaa cacatctttg agcaggactc tgaaagagta gaaatacttt
     2101 attaggagat ttccggaatc cttgcacccg ttatagtgct agagtataat aattttattg
     2161 tacttaaaga ggttagtgtc gtgaggcatt aatgaacaga ggtggaacca cgagagttaa
     2221 ctcccgtcct ctagcagaag ctagaggcgg gagtttttta atataatttt ttaagcgcgc
     2281 agagaattat attgcaatag atacactttt taaaaaataa tcaaaatatt ttaaaaatta
     2341 aaaggcgagg gagaatatta tgaaaaatat attaaaaaaa gtaggaatat ttacaattat
     2401 gttaggttta ttaggtggag ttgtaggttg ttcaaaacca gataatgaaa aagataagga
     2461 tgcttcaaag gaatctaaaa aagaagtagt tgtagggttt gataatacgt ttgtaccaat
     2521 gggattttta gatgaaaagg gagatacagt aggatttgac gtagacttag ctaaagaaac
     2581 atttaaaaga cttggaatgg aagttaagtt tcagcctata gattggtcaa tgaaggaaac
     2641 tgaattaaat gattcaaaaa ctgtagatgt attatggaat ggatattcta taacagacga
     2701 aagaaagaaa atagtatcat atacagaacc atatttacaa aataaacaga taatagttac
     2761 tctaagtgat tcaaaaataa attcaaaagc tgatttaaaa gataaagaag ttggaacaca
     2821 acaaggttca acagcacttg atgcagtgga aaaggataaa gattttatga atagcttaaa
     2881 aggtggagca ccagttcttt atgatactta tgataaagca cttagagatt tagagatagg
     2941 tagaactagt gcagttgttg gtgatgaagt tttaattaga tattatatgg gacaaaaggg
     3001 tgaagacaaa tacaaggtat taaaagacga ttttggatta gaagattatg ttgtagcaac
     3061 ttctaaagaa aatccagaac tttgtgagaa aataaataaa acattaaaag aaatgaaaaa
     3121 agatggaact tttgacaaaa tttatgataa gtggtttaaa tagaagataa gttagctgtt
     3181 aagaaggggg cactaaaggc atgttacaag gtttagagat agttatagca atgttttgta
     3241 taacattgat agtatcaatt ccattgggga ttggagttgc atttttaaga ttatcaaaga
     3301 ataaattagt aagtggtatt acacaatgtt atatattgat aatgagaggt acacctttac
     3361 ttttgcaaat gatagtcata ttttacggat tacctctttt aggaattgta tttgacagat
     3421 ttacagctgg agtagtagct ttcttcttaa attatgcagc atattttgca gaaatattta
     3481 gaggtggaat acagtcaatc gatagaggac aatatgaagc ttcaaaagta ctaggatttg
     3541 ataaatttac tatgtataag agagtaatct ttccacaagt ttttaaaaga atactagcac
     3601 ctatttcaaa tgaagtaatc acattagtaa aagatacatc tttagtatat atattaggat
     3661 taaatgatat tttaagaata tctcaaatag caatgaacag ggaagcaagt ctgttaccat
     3721 tatttgaggc aggagcgata tatcttatat ttgtagctat acttactaag ggatttgaat
     3781 tacttgaaaa aaaatattct tattatagat aaagttacaa tattatagga ggaggttttt
     3841 tatatgttga aaatcaaaaa cttaaataaa tcatttaaaa aaaatagagt acttaaagat
     3901 atttcttttg agttagaaga aggtcagatt ggagttttac ttggtaagtc tggtgcagga
     3961 aagaccacaa tattaagatg tataaatggt cttgaagaat ttgatagtgg agagattata
     4021 atagataatg aggtaataaa aaataagaga gatatggcaa aaatacgagg aaaaataggt
     4081 atggtttttc aaaatttcaa cttatttcct catatgacag tccttgaaaa tataattgaa
     4141 tccccagtta atgtttttaa agttcctaga aaagaggctg aagagagggc tagagaactt
     4201 ttaagattag ttgatttaga agataaatta aattcttatc catttgaatt gtcaggagga
     4261 cagcaacaga gagttgctat agctaggtca tgtgcattga tgccaaaagt cctttgtttt
     4321 gatgaaccta cttctgcact tgatattgat actattcaaa gagtagtcaa tataatgaat
     4381 agacttaaag acaaaggtat gacaatatta ataattacac atgatgttgt cttctcaaat
     4441 aatgttgcag ataaaattat aagtataaaa gatggtatag tagaaaatgt tcaaataaaa
     4501 gaaaaaattg tttagagttt tataaatata aactagggta gaattttata atataaataa
     4561 agggcaagta aaatcaaata tactatgccc ttttgttatc tcaaaattta atcttatatt
     4621 ttatgtttaa gttacattat aatttataat aaaaataaaa ggactattta aatatataat
     4681 gtgaataaat gtttaataat ttgaaatatg ataatttttt atgttgaaag cttataatga
     4741 ttatgatata aattggttat agtatacaat ttatgggtat aacaataaaa aattagaaag
     4801 gaatttttat aaaatgatta aattatatgg atatacaaaa tgctctactg ttaaaaaagc
     4861 taaaaattgg cttaaggaaa ataatttaga atttgaagat atagatatgg ttcaaaaccc
     4921 tcctagtaaa gaggagttaa aatcaattta taagactagt ggatatgata taaagaaatt
     4981 ttttaataca agtggtatga aatatagaga attgggtctt aaagatattg taaaaactga
     5041 atctgatgat aaacttttag aaatattggt aagtgatggt atgcttatta aaagaccatt
     5101 acttttggat ggtaaaaatg tattattggg ctttaaagaa gatgtatgga aaagtacttt
     5161 gctaaaagaa gattaggaag agataggtgt gttgattaaa attattaatt aatacaccta
     5221 taaatttatg tattaaatct aatctttata aatattaatt agcaaattca aatcaaaaaa
     5281 attcatatca acaaatatat tacttcttat tacaaattat atcatatgtt ttatattaaa
     5341 atattataat attacaacga attgttacaa aattacttat tattaaccat gaacatttgt
     5401 tttgtgctat catatttata taagggaatt gtcataaaaa atatcttgtt catacagttt
     5461 tatatagaaa aaagaaatga atcttttctt tatataagta tattttgtaa attgcctcta
     5521 tatttatagt ttaaataata gtggttttaa aaatctgaca acaaaaataa aactttcaaa
     5581 aaattaaatc taaaaagaat aggagataaa tatgagtatt gaagatttat atgattttga
     5641 atgtgttcct ttgaacaatg agattgatat tgatgtttta tttgaaaaga tgatagaaga
     5701 tggaaaagaa aaagaatata caccaattat agtcattgat gaaaaagtag ggctattaag
     5761 aaaaaatata gatatgatta ctaaagagta tggttctctt gaaaactata gagagtattg
     5821 tttaacaaaa tataatgaaa ttgatgtaaa tcaatttttt gattttagga agagtgagat
     5881 ttcagaatta ttaaaggagc taattgattt agaagatgat ttttatgatt ataaacattt
     5941 tagaccaatt ataaatatag atatatttca tgaatataac aaagtttaca tagctaaaat
     6001 tccaacaatt aaaccatatg aagtatttgc atacatacct attggaggat ttaatgattg
     6061 tcctagagat gaagaacata tagctattgc aaaatattgg tatgaaaagc atggaatctt
     6121 tccaatcgca attggatgtg atacagttca atattctgta aaaaatttaa ctaaagatgg
     6181 taaaaaattt gatgacttat gtattgaatt agtattttat tgtgaggata ttattataca
     6241 agggtatgaa accttaaagg ctcttaagga tgtattaaaa cgctctacaa tagtgctttt
     6301 ttggtgggat tgatattcta tcatttagat agtattaaat tgttagtcac caagaatcca
     6361 cttactttag ttatggggag tgtgtcaaac taggttttta tacacagtgt agcatagtaa
     6421 tatgtttaaa ttacaaaggt taaaaaaata ctttaatatt tttaatatta taattaatag
     6481 atttaaaggt aattataatt tataaaataa atactttata tgttataatc attaagaatg
     6541 taaaaaaata atatatagtt ttatagttca tatttttcca gatatggagg taaattttgt
     6601 gaaggaaaaa gaaaaattag ataaattaaa aaaaatgtta cttgaattag gcagtgttgt
     6661 agttgcttat tctggtggag tagatagtaa ttttttgctt aaggtcgcaa aagatacatt
     6721 aggtgaaaat gttatagctg tgaccattca tgcaatgatg cattcaagta gggaaattga
     6781 agaggctaaa caatatactc aaaattttgg cgttaaacat atcatattaa atatagaaaa
     6841 ctttgattta aaagaattta aagaaaatgg tgttgataga tgttatcatt gtaaaaaata
     6901 tatattctct aaaataaaag aggtagcaaa agaacataat ataaagtaca tagtagatgg
     6961 gacaaatatg gatgatttag gagactatag acctgggctt aaggcattga gtgaattagg
     7021 agtgattagt ccattaaaag atagtagttt aaaaaaagaa gaaattaggt cgctttcaaa
     7081 aatattagga ttaaatactt ttaataaacc atcatttgca tgtcttgcaa gtaggattcc
     7141 ttatggagtt gagataacag atgaaaattt aagaatagta gaaaagagtg aagaatatct
     7201 attcaattta ggtttttctc aatttagagt gagaatgcat ggagagatag ctagaataga
     7261 agttgggcag gaagaactag gtaaattttt tgaaaataac aattttaata aagttgatac
     7321 taaattaaaa atatttggct ttaaatatgt tacactagat atgtcaggat ataaaatggg
     7381 aagtatgaat ttaaatgtgt agattatttt aaaaataaat aagttttata gttaatataa
     7441 ggaaacagga ggttttatga aaaattatac attaatatcg ccatgttttt ttggaatgga
     7501 aaaaatgctg gctagagaga ttactaattt aggatatgaa ataataaaaa cagaagatgg
     7561 aagaataaca tataaaactg atgagtttgg aatagcaaag tcaaacatgt ggttgagatg
     7621 tgctgaaaga gtacatctta aaattgctga atttgaggca aaaagctttg atgaattatt
     7681 tgaaaataca aaaagaataa actggtctag atatatacct tatggagctc aatttcctat
     7741 atcaaaagct tcctctataa aatcaaaatt atacagtaca ccagatgtac aagccatagt
     7801 aaaaaaggct atagtagaaa gcttaaagaa aagttattta gaggatggtt tgcttaaaga
     7861 agataaggag aaatacccta tttttgtatt tatacacaaa gataaagtaa ccatttctat
     7921 agatacaaca ggagatgctt tgcataagag aggatataga gaaaaggcaa ataaagctcc
     7981 aataagagag actttagctg ctgggcttat ttatttaact ccctggaaag caggtagagt
     8041 tttagtagac cctatgtgtg gttctggtac tatattgatt gaagctgcta tgattggtat
     8101 aaatatggca cctggcttaa atagagagtt tatatcagaa aagtggagaa ctcttgataa
     8161 gaaaatatgg tgggatgtaa gaaaagatgc ttttaataag atagataatg aatctaaatt
     8221 taagatttat ggatatgata tagatgaaga atctatagat atagctagag aaaatgctga
     8281 aatagcaggt gtagatgaat atatagagtt taatgtagga gatgcaactc aatttaaaag
     8341 tgaagatgag tttggattta taatcactaa tcctccttac ggagaaagat tagaagataa
     8401 agacagtgtt aaacagttgt ataaggagct tggttatgca tttagaaaat taaaaaattg
     8461 gtcgtattat ttgataactt cttatgaaga ctttgaatat gagtttgggc aaaaagcaga
     8521 caaaaaaaga aaattgtata atggtatgtt aaaaactaac tttttccaat atccgggtcc
     8581 taagcctcct agaaataata aataagtttt acatgattta tttgtaaaat ataaaatttt
     8641 attaaaataa gtaaaacatt atgatgcctt gaaacgtcta attattgtga ggagattttt
     8701 gtgaacaaat ttaaagattt ataggattag gaggagttaa atgaaagtgt taaagcttat
     8761 tactgtagta gccctgatga tgttatttgt tactggatgt aatataaaaa ctgaatctcc
     8821 agaacaatta gcgaagatac ctgactatga tgatacaaaa aaagtattgt atgatggtat
     8881 tgaccagtta ctaaaaccag attcatctat gatattgcct tctaatacaa aagaagtagg
     8941 aaaaataaat aaggtagatt taaacagcga tggaattgat gaattagtag tatttgaaca
     9001 aaaagaagat ttaagtaata atgtgagtca ggtagggttt gtaaccttga gttacaatgg
     9061 agaaaaatac gtacttggag accatttttt agaaaatggc gaatcaatag aatatgctaa
     9121 tttttatgat ttggactcag atggatataa ggaagttatc ttattggtta aatccaaaga
     9181 caaaacgaat atgcatatat ataaagtagt agataatgaa ataacaaaaa tatatgactt
     9241 ggatgcatca tggcttcaaa ataaagaaga ttttaatgac atgaaagtaa aaattggata
     9301 tatagatgga gatgacaagt tagacatatt gatgcttcat ttgaataata agactaatga
     9361 aatgtttgca agtgttgcaa attttgatgg gaaaatgaaa atcaaagatt ctgttaagtt
     9421 tgaaaatgta aaaaacttaa gtgaattata tacaacatta ggtaatgttg cttcatctgt
     9481 tggaaattct tctgcagcta taaaaggtat tgtacttgat attcctatat tgaaagataa
     9541 taactatatt acgcagatac tttatatgaa agatgggaaa attaacaaag cttttagtga
     9601 ttatgataaa actattacta aatcttatta tatacctgta gatgatattg acaaagataa
     9661 gattatagaa atacctatag ttgcaggcag tacaggtaat aataaaaata cttatagttc
     9721 taaatcatct gcaactataa gttggtatag atggaatgga aaagaaggtg ctgactcaag
     9781 tttaatattt acaagtcaga tatattataa ttataaatat aattttaaat tatttattcc
     9841 aaataattta tttgataaaa tacttgttga acaggaattt gttggagaaa aagcagtatt
     9901 taaattttac tattttgact attcagatcg taagaattta tttaatatag tagtagagag
     9961 taaaaacaaa cttgaagata gaaaaaatac aggtactcaa aactctattg tacttcaaga
    10021 gagcgatgaa tatactttct tactagttgt aaacaatgca aatgaaatgg ataagctaga
    10081 tatgactata gacgcattaa aagaatattt ctcattaata tatggttaat attatactca
    10141 attggaggtt ttattttatg aaggaaaaga tacttatact agaagatgaa attggtatta
    10201 gaagttttgt tagtataaac ttaaaaagag aaggctatga aatagttgag gcaggtactg
    10261 gaagagaagc tatagaaaaa atgacaacag aaaatgatat tacaatagct cttttagatg
    10321 tgatgcttcc agatataagt ggtatagaag tatgtaaatt tataagggag aattttgacc
    10381 aagtaggtat aataatgctt actgctaaag ctcaagagga tgataaaata gaaggattta
    10441 tttcaggagc agatgattac atcataaaac catttagtat aaaagagctt ttagtcaggg
    10501 tttctgctct tcttagaaga gtagcaaagg atgattcaag tgttaagtcg agtgaaatag
    10561 tttctccacc atttatactt gatatagaca agagaaaatt atttaaaaat ggaaaggaaa
    10621 ttgagcttac accaactgaa ttttcaatag tgaaatatct aatatcaaat gctaagcaat
    10681 cgttaagtag agaccagata ttagacgaag tatggggaac taactattta tatgatttta
    10741 aaatagtaga tgtaaatata agaaggataa gaaataaaat agaagatgac ccatcaaagc
    10801 caaaatatat acaaactatt tggggttatg gatactgttt tagaaaggaa gaataatagt
    10861 gttacatttt gaaggtctga gaaaaaaagt aataaaaaac tattttataa taattattat
    10921 aatggttact ctgtttgaag gattgttcat gttttacata caaaactact attatgattc
    10981 tgtcaaacaa ctacttgaat ctgaaataaa atatgctgat gaatataatg ctattacaat
    11041 ggaaactaca agttttgaga aaaaagtaaa aaatatattt gataaacaac cattaactaa
    11101 aaattcagaa tttggaattt caataataga taaagataaa aatattatat tagaccaata
    11161 tggttttaaa agtaaagaaa aagcaaacta tgaagatgtt aacaatgcat taaaagatat
    11221 aaaaactaaa aatttaacac cttatactta tagaatacca gatacagggg agcatgttat
    11281 gagtatctcc ttaccactta aggtaaataa tataatagaa ggtgttgtta gatatacagt
    11341 atcattagat gctattgata atgcaatatt aaagcaagct acatggctta tattagcagg
    11401 aatatttata cttattatag ctatactaat aagtcttaaa tttgctgaga ctcttataaa
    11461 accattacga gagctaaaga aatttgcaaa tgaattggct gtaggaaatt ataatataaa
    11521 attagaaaag atgaagattg tagatgatga gattggtgat ttagcacaga catttgaaca
    11581 catggcacat gagattgaca aaagtgaaaa attaaaagag gaatttatat catctgtatc
    11641 tcatgaacta aggactcctc ttacatctat aaaggggtgg agtgaaacct taggttatga
    11701 aagtataaca agagaagaac tagacttagg tttaggcatt atacaagatg aaacagaaag
    11761 acttataaaa ctagttgaag aattattaga cttttcaagg ctttcttcag acaggataaa
    11821 acttcatgtt gatatagttg atgttgaagg tttaattgta ggtgttgtaa atcaacttaa
    11881 agttaaagca gctgaaaaag atatatcact tttatttgaa tttgaaaatg aatttataga
    11941 gaacattcaa ggagataaaa atagattaag acaggttctc ataaatttaa tacaaaattc
    12001 atttaaattt acgagtcaag gtggttacat aaaagttgta gcttctcaag atgaagagat
    12061 aacaaccata tcagtagagg ataatggttc aggtatagaa aagcaaaatt taaataaagt
    12121 gttagataaa tttttccaag aagattataa taaggctggt agtggattag gattagcaat
    12181 tagtaatgaa attgtaaaac ttcatggtgg aagaatgaaa atagaaagtg aaaagaatgt
    12241 tggaacaaaa ataactttta atataaaaaa taaatttgct aaacaagcat aaattcttag
    12301 aaagaggatt aagatgagaa acataaaaat gatagtagca tacgatggtt caagatataa
    12361 aggatatcaa aaattaggtg acaataatat gactattcaa gaaaaacttg aaaatgtttt
    12421 aagtaaaatg actaatgaaa cagtggagat aatagggtct ggaagaactg atatgggagc
    12481 tcatgcaaga ggacaagtgg taaattttag aactaattgt atggattctt tggataaaat
    12541 tcaaaaatat ttatatgaat atttaccaga agatatagtt gtaaaaactg ttgaagaagt
    12601 tgatgaaaga tttcattcaa gatacaatgt aaaatcaaag acttatatgt ataaaattga
    12661 caataataag tatcacaatc cttttataag aaaatatgct actcatgtaa gtaaaaaatt
    12721 agatttagat agaatgagaa aagcaagtga gtatttagta ggagaacatg attttactag
    12781 ttttgcttct tctaaatcta agaaaaaatc aaatgtaaga gaaatttatt ctataaatat
    12841 aaaagaagat gataatgtta tagaaatata tgtagaagga aatggatttt tgtacaacat
    12901 ggtaaggata atagtaggtg ctttgataga tgttggtcta aaaagaagag ctccacaaga
    12961 tattaagtat atgcttgaat caaaagatag atgtcaatca tcagatactg caccagctaa
    13021 aggactatgt ctttggaaag taacatatta gtcaattata taaaactctc tttaaaataa
    13081 aaataaaata aattatatag ttgacataaa tggaaaaata aactattata tattttataa
    13141 gagagatata aaactttata tttaaatcct gtgagaaaga gagtaacttc tatgtgtttt
    13201 atagagagct gaggatggtg gaagctcagc aaataagtat tagtgaaaag aactttggag
    13261 gatactaatt gaatttagta tgttagtagg taatctcgcc ttaagagaaa gagtggataa
    13321 gtttatctta tcaattagag tggtaacgcg gatatatttc gtctcttggt ttttccaaga
    13381 ggcgtttttt aatatattta attattagtg tttatctggt atgttgaaca tttactaatt
    13441 gattagctaa gtttatcaat aagagtggta ccgcggatat ttcgcctctt agtattttaa
    13501 aatactaagg ggttttttta gtattaaaat gattttatgt gagtctaaat tctcagagtc
    13561 attcaatatt aagaatttct ataaaataaa aattataatt taagattggg aggaattaaa
    13621 aatgaaggaa aaagtagtat tagcatattc aggaggactt gacacatcaa tcataatacc
    13681 ttggttaaag gaaaattatg aagatataga tgttatagct gtttgtggaa atgtaggtca
    13741 ggaagataaa atggaagatg tatatgaaaa agctttacaa agtggagcat caaaggcata
    13801 tgtggatgat ataagtgaag aatttgtaac tgaaactata tttaaagccg taaaagcaga
    13861 ggctaaatat gaaggaaaat acttattagg aacttcttta gcaagaccta taatagctaa
    13921 aaaattagtt gaagttgctc ataaagaagg tgcaaaatat atatgccatg gatgtacagg
    13981 aaaaggtaat gaccaagtta gatttgaagc tacaattgca gctcttgacc cgactataaa
    14041 agttattgca ccttggagaa tttgggatat aaaatcaaga gaagatgcta tagactatgc
    14101 tgaaaaacat aatataaagg taacagcaac taaagctaaa atatattcag tagatgctaa
    14161 cctttggcat gtttcaacag aaggtggaga tatagagcac ctagaaaatg aacataaaaa
    14221 agatgtttat aaacaatgtg tagacccaga agatgcatgt gatgtagctg aatatgtaga
    14281 agtttacttt gaaaaaggtg tacctaaaaa agtaaatggc gaagaattat ctccagttgc
    14341 actgattcat aagttaaatg agttgggttg taaacatgga attggtgtta tagatatagt
    14401 tgagaataga cttgttggta tgaaatcaag aggtatatat gagactccag gaggaacaat
    14461 cctttatgaa gcacataata ttttagaaag tgctacttta gacaaagata cattacattt
    14521 caaacaaatg gtatcttata aatacggaga acttatttac aatggactat ggtattgtaa
    14581 attaagagaa tctatagatg catttatgga acaaactcaa gataatgtta caggaacagt
    14641 aaaagttaaa ctttacaaag gaaatataaa acctgctgga atatttactg aaaatgctct
    14701 ttatgatgaa ggaatatctt cttttggaaa tagtgaactt tatgaccaca aagatgcaga
    14761 aggatttatt aatttattca ctttaccatt aaaaatcaga gctatgaaag ctggaaaata
    14821 ataaaataaa ttatttaaga gtgtataaaa actattttta ggtttttata tgctcttttt
    14881 ttatttgaat ttattaaatt atacagtaaa tagtataaaa aaatatatta tagttccaaa
    14941 tgacttaata atgtgaaaat ataagaccta aaatataaat tttataaata caatagttat
    15001 tgactctctc attgtaagag ggtttatact gaatctaatg aaaatttata gtgaggagat
    15061 agattatatg agaaaaataa ttgaaattaa acatcattca catgattatg agtgtatgtg
    15121 gaatggtata gaagatttat atataaataa aaccggtgaa tgccttccaa acgatttttt
    15181 ctttttactg tcaggttttg gttcattttg ttatatgaaa acaaataaag ctgatttgaa
    15241 aagaatggta gctttgggag atggaaggac aaaacagatg tataaatttt tagcaccaat
    15301 tgttggattt gaatacaaac atcatgagtt taaaaagtat gagcaagcat taaagaaagc
    15361 aaaatctgaa attgatggtg gatatccagt tattttagga gctttagata tgtattatct
    15421 accatattat aagaagctat atcataaaga acacattcct tttcattata tattaatggt
    15481 aggatatgat gatgaaagaa tatatctgta tgattgtggt agaacagaat tattacatct
    15541 ttcttatgat aaattacgtg aaagcatgaa ttgcaattcc cctggattaa gcaaagaaaa
    15601 tactatttgc acaataagaa tgaatacttc aaagaataaa tataacattg ctagagaagc
    15661 tattgctata aagcgtgata tgtttttaaa tccatctaaa ggatttttgg gatataaagg
    15721 ttttgaaaag tttattaaag agttgccaca gtggaacact gaattggata aagatgatta
    15781 tgataagatt ttgaccaata tggttatgtt ttttggaaca gtaccaacaa ttccaaatgc
    15841 aatcaaagga attaaagaac cagatactgt tcaatttaaa ggtggatttg ataaaatgag
    15901 tagaatgctc aacagtattg gggaggaata caaaaacgac tcttttatac aagtagctga
    15961 tatttttgat aaaactgcta ttataattga gaaaatatcc aatattataa tagattattt
    16021 aactcaaaca tgtgatgata cagaacaact tccgttattg ttctctgagg tcttagagca
    16081 tatgaaaaca ggatatttaa tcttggatgt ataaaaaata tattgttgac cctaacatta
    16141 cgtaatagtg taatatgaaa atatagcttg aatatattag taggtattga tggctgtaaa
    16201 attaaaattt gaggtgtgga tatgagaaca gtgaaacaag tttctgattt aactggaata
    16261 agtgtgaggg cattacatta ttatgatgag ataggtcttt taaaaccaaa taaaattaca
    16321 gatgcaggat atagacttta tgatgatgaa tctattaaaa ctcttcaaca aattttattt
    16381 tttaaggaga ttgatattcc tttaagagag gttaaggaaa taatgtcaag ccaatatttt
    16441 gataaggttg aagctctaaa aaatcaaaaa aaattactta ttttaaaacg aaagagactg
    16501 gatgaattga tagagcttat aaatcaaact ctaagaggag aaggaaatat tgattttaaa
    16561 gagtttgata tgagcgagta ttttaatgtt ttagaagaat ttaaaagaga acataggaat
    16621 aagataatta aaatttatgg tagtgtagaa aaatacaatg aatatataga aagagttaag
    16681 tctaatgaag agaaaattgc taaaatggct ataaaacaat atggaactat tgagaagttt
    16741 gcccaagcta taaaaacaaa ttttagcagt gatatattga atttaggaga aaaatttgat
    16801 agatataaaa atgattgttt aaaagaaaaa catccaaaat taaaagaatt atatagaaag
    16861 cttgtagaag atttaagtaa gaatccttct tcaacagacc ttcaagaaat agcaaaagag
    16921 ataacagata tatctaaaaa agattatgaa attttctcta tgtatactgg tgatgacaac
    16981 tggtattata tgattcaaaa ttatctagta aatcctatgt ggatagaaga agtagataaa
    17041 aagtatggaa gtggagcagg caagtttatt ggacaagtac taaagactta tctaagagat
    17101 agaaaaccaa agataaatac attgtatgaa aaacttgtag aagatttgag tagagattgt
    17161 tcttcaaggg aagttcaaag cattgttgaa gaaatagaca atgaaatgaa aagaagtaat
    17221 gaattttata aaatagacaa tggtgaaaga tactttgatt atatgtcaga gctttattta
    17281 caagattcta actatataaa agtaactgat aagaattatg gtgatggtgc atctaagttt
    17341 attggagaag cttttaagat ttattttgat aataataatt gttgaaaatt tggaagtaaa
    17401 aaatatgtaa gttttataaa agcacaaaaa taaggatgta gattagctcc atctatatcc
    17461 ttatttaaag ttattaaaat atatagttta catcaaactt aacactttca ataatatttc
    17521 ccaaatatgt ttttatactt tcaacttctt ctaaagattt taatttattt tcagtataaa
    17581 ttgctttgtc cagaatatta aaccttaatc ctatttcatc aaagtactca tgatttaaaa
    17641 ctttgtacca atggtttttt tctttattcc aactcgtaga tattgaatca gcttcttttt
    17701 gagctttttc ccaatcttca ttttctatag atttttctaa aacagatata ttgtctttat
    17761 atccttctgt aaaatcatat agtttattgt taacgtaaaa tccaaataat acaaataaga
    17821 tagtccatag tataacaaat gttgtagatt tcaatattaa tcaccctttt tattttgaat
    17881 aaatattttg tcattttcat ctaaaacaca aataagaaca tctttaaaag tttctatgtg
    17941 attagatttt aaaataccca ttaaccagtt agtatctttt tgagctatgt ctagattttt
    18001 atttattatt ctaccatcca gtataagtgg gataggtaaa tgattaaaag ctcttggagg
    18061 agtactattg tagcttgatg ctggtacaac acttagatta ccatcagtct ccaaaatagc
    18121 atattgtaca tcttttaggt tgaagtatcc ttgaatccta agttgttcta ataattcatc
    18181 tatactaatt ctttcttttt taagctcttt atatacaatt tttcctttat ctattaatac
    18241 agaaggttta cctgataaaa atgaacttaa ttttctgctt tttaatgata agaatgaaat
    18301 aagagtctgc atgattacaa gaccagatat tgctgcaaca ccatttatga ttggtatatt
    18361 attattttcc attgggacag atgcaacttc tgcaattaat agtgttataa ctaaatcaaa
    18421 acagttcatt tcagctattt caccttttcc catgactcta agtgcaatta gcactgttat
    18481 gtataatata atacttctta ttaatactac tgtcatatct atcaattact cctttaaaaa
    18541 atatttacac ttagttagta tatcctatat aaaaaattta attcaaagta taaaaaacct
    18601 taaataattg gattcaacta tttaaggttt ttttgataat tttaatatta aattttttat
    18661 ggattttctg ttacttttat ttattttaat aacagattca acaaaactct ttttatctcc
    18721 taattttaag ataaaatcag gatattcttc aaattcattg agttttatta atttgaaaga
    18781 agaagataga tttttaaagt taatgatttt agagttattc actaatacac ttcttttttt
    18841 aaaataaatt tcttttttac ttatatttag tatagttaat atttgtttaa gatatattat
    18901 tatatcttct ggagttctat caaatttgag ttcaaaattt tcatcttcaa agtagggaat
    18961 ataatataaa ggtgttttga gagcaggtaa tttattatat aattcttcaa gaatatcgat
    19021 atttttaggg gagttaaaga aaaagcattt acatacgttc attaaatcca cagcatctga
    19081 aagtgagtta tgtttaatat ctccttctac agaaaaaatt tttttcatat tcagtaaaga
    19141 tatttgctta gataagattc tattattgta tgtaatatgt tgagatataa aaggttgaat
    19201 gtcaatcatc atattaaata actctaagca tttacctgta tatttatata ctctaaatga
    19261 agttagaagg ccagttatat caaaatcacc ccaattatat attgtaacat catcaaattt
    19321 acaaaaccat ttataaaaat catccataac atataaaaga ttaggagcat tattgatatc
    19381 tagttggttc aatttggtta aatttttaca tttatttgaa agtattttat tgtattttgg
    19441 cttaactaaa gagtaataat tatctattgt attaaattcg ttatcaacta aaactccacc
    19501 aatagaaatt aattccgcac cattatattc ttttggttta tttttattat catctagtat
    19561 attaaattca aagtctataa ataacttgta tttcataaat ctaaagcaca tcctcaggta
    19621 aattatttat tgagcctaag catcataaga atcaatagat ataatgactc taaacatcaa
    19681 aggttcatta caacttttat ttatttcata atttaattca aataaatctt ttaagatata
    19741 atttataagt attctttccc aacccatttt taaattaact ttagagtcta ttaatatatt
    19801 ttctatcttt ttaaatattt ctatatttgc tggtattata ctgagctcaa tattactttt
    19861 aaacgggtta gactgtaaat ctgttataag tatatttttt aattcctctg taagttcaga
    19921 aattaaacta tcacctatgt atttttttat gatttcctct ctaatttctt ttaaatttag
    19981 caatattagt acctgctact tacatagtag cttttccttt ccttttaata ctattattca
    20041 tttttgaatc ttatttagat atattttaag attaaaagtc tttagctata taatttttta
    20101 cccattttta acttatatta acatattaca ggcttatatc tccaccctgc ttacattgag
    20161 gatggagtat attgcctatt ttgataaaaa tgataggttg ttatttgcct attccttttt
    20221 ctgataattt ttctaacata tctttggtca ttttatctaa atcataacta aacttaaagt
    20281 tccattcttt tactgcacta ctactgtcta gagagttagg ccaagaatca gctatacttt
    20341 gtcttacagg gtctacatca tattctatca caaaatcagg aatatatttt tttatagaat
    20401 cagctatttc ttcaggagaa aagctcatag cagtaatatt aaaagcattt ctatggatga
    20461 gtttatccgc tggagcttgg attaaatcca ctattgattg aagtgcatca ggcatataca
    20521 tcatatccat ttttgtacct tctgctatgt aagatttata tctcttattt tttaatgcct
    20581 cataatatat atcaactgca taatctgtag ttcctccacc aggaggcgta acataagaaa
    20641 taagacctgg aaatctaaca cctctagtgt ctactccaaa ttttgagtga taataatcac
    20701 atagtaattc tccagaaact ttagtcacac catatatagt attaggtctt tgtaatgtat
    20761 cttgaggagt catatttttt ggagaatttt caccaaaagc agcaattgaa ctaggtgtaa
    20821 aaaatttaca atccaattct ttggctattt caaggccatt tattaatcca ttcatattta
    20881 agttccaagc ttctaggggt ttactttcag caactgcaga aagtaaagat gctagatgaa
    20941 ttatagtatc tacatcatat ttttttgcaa tttcaaaaaa acgattctta tctgtaacat
    21001 ctaatatctc aaatatacca gattcacata ctggattacc ttcttttact ctccttgaac
    21061 tagcgattac attttgttct ccatactcat ttctaagctt tattgttaat tctgaaccta
    21121 tttgtcctaa tgcacctgtt ataagtattt ttttcaattt tacaacctcc taagggttta
    21181 atttatgtag tactacttat ttttatttta gcaaatcttt tgtttaaata caaagaatta
    21241 aagataataa tatacgactt aattgaatga agtgcagtaa attcctaaaa atttaaagtt
    21301 gagatataat ggtctattgt ataacaataa aagactagat taaattatta tatagattgt
    21361 gtgactaagt cacagaaagt atagttaatt taatatataa taaaagcata tcaagtaaag
    21421 ctttaaatta aagtaacttt atataaaaag taatataaat tgataaaatt ataaatttat
    21481 ttatagtgaa tataggttgg attttataga tacaaaaata gtatatatga tatgtagacc
    21541 attagcatgt ttaaagtagc aaaacatata aaataaaatt tgaaaggaag tataaaaatg
    21601 acaagaccat caatatatca tagccaagga tacacttgtg cagaggcatt aataaagtct
    21661 tataatgagg aacacaacac agatatacca atctcaatag gaagtggtat gggggttgga
    21721 atgaatgttg gaagtgtttg tggagctgta aatgctgctg ttgttataat agggtattta
    21781 aatgggcgaa atagtaattt agatgaaaat atagcaagga agtattcaag agagctattg
    21841 aataaagtaa gaaataaata cagctcagaa atatgtgtat ctcttaaaaa aaataaagta
    21901 acttgtgaag aaataataaa tttcacatat gatgctctaa atgatatgct aaaaaatcaa
    21961 aaataattct aagaaacaag tattttacat tcgatagaat acttgttttt ttatgatatt
    22021 tttaataggt attagtttat tataattttt aaatcaattt tattatattt taattgaaat
    22081 aatctacttt gaaaattact aactgacaaa ag
//
LOCUS       DAMJWO010000071        22011 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.072, whole genome shotgun sequence.
ACCESSION   DAMJWO010000071 DAMJWO010000000
VERSION     DAMJWO010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22011
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.072"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(211..354)
                     /gene="scfA"
                     /locus_tag="PC366_002752"
     CDS             complement(211..354)
                     /gene="scfA"
                     /locus_tag="PC366_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HDF2578250.1"
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
     gene            complement(420..782)
                     /locus_tag="PC366_002753"
     CDS             complement(420..782)
                     /locus_tag="PC366_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HDF2578251.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEVGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            complement(840..1133)
                     /gene="yajC"
                     /locus_tag="PC366_002754"
     CDS             complement(840..1133)
                     /gene="yajC"
                     /locus_tag="PC366_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HDF2578252.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSV
                     GDKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            complement(1267..2388)
                     /gene="tgt"
                     /locus_tag="PC366_002755"
     CDS             complement(1267..2388)
                     /gene="tgt"
                     /locus_tag="PC366_002755"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HDF2578253.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITSIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPQDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            complement(2467..2952)
                     /locus_tag="PC366_002756"
     CDS             complement(2467..2952)
                     /locus_tag="PC366_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578254.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKS
                     I"
     gene            complement(2964..3989)
                     /gene="queA"
                     /locus_tag="PC366_002757"
     CDS             complement(2964..3989)
                     /gene="queA"
                     /locus_tag="PC366_002757"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HDF2578255.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFLYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGNNVICVGTTSCRTIESACNEDGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            complement(4307..5326)
                     /gene="ruvB"
                     /locus_tag="PC366_002758"
     CDS             complement(4307..5326)
                     /gene="ruvB"
                     /locus_tag="PC366_002758"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HDF2578256.1"
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            complement(5433..6035)
                     /gene="ruvA"
                     /locus_tag="PC366_002759"
     CDS             complement(5433..6035)
                     /gene="ruvA"
                     /locus_tag="PC366_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HDF2578257.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASSAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            complement(6028..6537)
                     /gene="ruvC"
                     /locus_tag="PC366_002760"
     CDS             complement(6028..6537)
                     /gene="ruvC"
                     /locus_tag="PC366_002760"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HDF2578258.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKVIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            complement(6849..7478)
                     /locus_tag="PC366_002761"
     CDS             complement(6849..7478)
                     /locus_tag="PC366_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578259.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKNNGVQTSK
                     VVSASANMDEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMNATIKGKYTIENDNGNIALYK
                     YDDSGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            7681..8004
                     /locus_tag="PC366_002762"
     CDS             7681..8004
                     /locus_tag="PC366_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HDF2578260.1"
                     /translation="MERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLD
                     ESIYSNLSSNVNNRNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCS
                     SFECK"
     gene            8272..9126
                     /locus_tag="PC366_002763"
     CDS             8272..9126
                     /locus_tag="PC366_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578261.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHNIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKLITQETIENKLESLVENRLDTLEDRFE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(9312..10748)
                     /locus_tag="PC366_002764"
     CDS             complement(9312..10748)
                     /locus_tag="PC366_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HDF2578262.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNELLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPVETNLLKSEVERLSGKLFQGEIIMPFFKEGGRF
                     TIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSDIGEWCEEKTHGKYKSSDMIYISSK
                     ELRELNIEAITEKLKKAEGFNKIIVNATDYVDVKVFTIAFIRAVNSGKEFMFRSAAAI
                     TKVLGGVSDKEMLTKDELVSKGNTNGGIILVGSHVNKTTQQLEELKNCKYPIEFIEFN
                     QHLVLQENGLKNEVKRVIKVVEEKISSGKTVAVYTRRERFDLDTNDKDKQLMISVEIS
                     DAVTSIIGMLNVRPNFIIAKGGITSSDVGTKALRVKKATVMGQIKPGIPVWMTGKESK
                     FPNMPYIIFPGNVGEISTLRESVEILMG"
     gene            complement(10819..12201)
                     /locus_tag="PC366_002765"
     CDS             complement(10819..12201)
                     /locus_tag="PC366_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF2578263.1"
                     /translation="MITGYGLLIAFVISIGILLVSIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAVLIGGWIYGKRFEKYPAYAIDENDREKN
                     LEKGKDSIKIEDDDSSKVPGFGISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKRYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMVLLLSV
                     INGIIPLPGL"
     gene            complement(12337..13242)
                     /gene="garR"
                     /locus_tag="PC366_002766"
     CDS             complement(12337..13242)
                     /gene="garR"
                     /locus_tag="PC366_002766"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HDF2578264.1"
                     /translation="MEGYKMKLGFIGLGIMGKPMAKNLLKDGCNLLVYDINKSAVDEL
                     ISCGAKYASVLEMGQECDIVFTILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTP
                     TESILCANKLKDMGLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSS
                     SILIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLAGSTI
                     LDAKIPMIMNRDFKPGGKISINLKDIKNVMQTAHNLDVPLPMTSQLLEIMQTLKVHGH
                     LEDDHSGIAQYFEKLAGVEIKKHNN"
     gene            13638..14303
                     /locus_tag="PC366_002767"
     CDS             13638..14303
                     /locus_tag="PC366_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2578265.1"
                     /translation="MATFKRLQEQAYDYLKELILSGEMIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIVEIFQIRSAIEGFCTFLITSQYKEA
                     RAVETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDVYKTTLIHMETPKYINLEDFC
                     NNK"
     gene            14411..14959
                     /locus_tag="PC366_002768"
     CDS             14411..14959
                     /locus_tag="PC366_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578266.1"
                     /translation="MIFLNENVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTIEILRKVLFERSEERAIAMRERALENGDELIADNIISTTDVPFLGWVPEFKE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            15221..15529
                     /locus_tag="PC366_002769"
     CDS             15221..15529
                     /locus_tag="PC366_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578267.1"
                     /translation="MFNKIYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(15691..17481)
                     /locus_tag="PC366_002770"
     CDS             complement(15691..17481)
                     /locus_tag="PC366_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578268.1"
                     /translation="MKKSKGFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGVPGASVNFDYVTKILVILACIYFANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQSRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADKESE"
     gene            complement(17481..19208)
                     /locus_tag="PC366_002771"
     CDS             complement(17481..19208)
                     /locus_tag="PC366_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003496244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578269.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSILLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKDTENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSARVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            complement(19453..20017)
                     /locus_tag="PC366_002772"
                     /pseudo
     CDS             complement(19453..20017)
                     /locus_tag="PC366_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426623.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
     gene            20306..21418
                     /locus_tag="PC366_002773"
     CDS             20306..21418
                     /locus_tag="PC366_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDF2578270.1"
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     AEAASKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
     gene            complement(21601..>22011)
                     /locus_tag="PC366_002774"
     CDS             complement(21601..>22011)
                     /locus_tag="PC366_002774"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDF2578271.1"
                     /translation="NVAKDLFNGEIVAYEISTKMDTKLVNKTVNQLINMNLAKDCILH
                     TDQGSQYTSRSYSKRLKDNGIIQSMSRRGNCWDNAPIESFFSHFKSELIYLIDTTDPK
                     EMISLINDYIYFYNNERIQLKNGMSPIEYRTHSA"
BASE COUNT         7341 a         3734 c         2618 g         8318 t
ORIGIN      
        1 aaaaataaaa tataagagta gctactttaa aataaatgct cttatatgat tagatatttt
       61 tgcataatta aacgataaga aatcaaattt aattttacat aagtagaata tatattttta
      121 tataataatt gaaaataaaa gaggatacct cataatgata aaagaatcac tttgagatac
      181 cctcttacaa acaactaaat caataatttt ctatctttca cactcttgat ttgcaactgt
      241 acaagaagtt ttacaagctg attgacaaga agtttgacac tctccacatc caccttttgc
      301 agcactttgc tttaaagtag cttgagataa agtttttaca tgtttatttt ccattttcaa
      361 cgcctccatt tctaattgtt tcctattgat tatatcataa aactacttta atataaactc
      421 tatttaaagt tgacacccaa tacgcctcca atgcctcctg ctgctgatat tagcaataac
      481 ttataaatca tccctacttc aaatacaaac ttttcttgtg ctaaaaacac agtcaaaaaa
      541 atacatacta tgtacaaaag tcctactaaa agtccataca taagtccttt ttctttcatg
      601 tgttttgaag tgtaaaaccc tcctatagct gcagaaatag tagttataaa tgatgagacc
      661 atagttatat tatctccacc aatatctgta aatgtcaaaa ataagttata cactaataaa
      721 acagccaaag ttattatata tgcatatcct agacctttaa aaatataatt agattttccc
      781 ataaaaaaac ctcctctcaa attaatatat attcgagaaa aggcttttaa attactaatt
      841 tagtcttctt ctatttcttc ttttttagat ttaacagttc ctatagccca tttttcaaat
      901 ggaactttag ttctatttgg tcctaattct aatattacaa catcatcttc aactttagct
      961 acattagcta ctattccacc tattgtaatg accttgtctc ctacacttag gctacttctc
     1021 atttctttta attgtttgtc ttttttcttt tgaggtctaa tcattaggaa ataaaagatt
     1081 gcgattacta ctacccatag acctatactc ataattattt gttgctgtgg cattaatttt
     1141 tcactccttt gtaaattata ctcttttgta aatcataata aatgtttata taacaattta
     1201 ctttctctat ctttgagtac tattgaatat tatatattaa aatgattata attaatagtg
     1261 caaaacctat atttcatatc catattttgc aaaaaattca tttctaaaat caagtaatct
     1321 atcttccatt atcgcttgtc ttatttgttt cattaaattt aataaaaagt gaagattatg
     1381 agtagttatt aatcttgcac ccagtatttc atttgctttt ataaggtgtc ttatataagc
     1441 tcttgaatag tttttacaag cataacaatc acattcaggg tcaagtggag taaagtcttc
     1501 agcataagtt gcatttctaa ctactacttt accttggcta gtcattgcag ttccatttct
     1561 agcgatacga gtaggtagga cacaatcaaa catgtctact cctcttataa caccttccac
     1621 taagtcatct ggactaccaa ctcccattag gtatcttggt ttatcctgtg gcataagtgg
     1681 agttgtatgc tctagcacgt catacataag tggttttggt tctccaacac taagcccacc
     1741 aatagcatat cctggtaaat caatactagt tatttctttt gctgattgtt ctcttaagtc
     1801 tttatacatc ccaccttgta ttataccaaa taaagcttgt ttgtcggtat tattatgggc
     1861 atctttacat ctttttaacc atcttgttgt tctttctaaa gaatttttta catattctct
     1921 atctgatggg tatggtgcac actcatcaaa cgccatcatt atgtctgaac ccaatgcatt
     1981 ttgtatttcc atagcttttt ctggagttag aaaatgtttt gaaccatcta agtgtgacct
     2041 aaattctaca ccttcttctt ttatctttct taaaggccct aagctaaata cttggaaccc
     2101 tccactatct gtaagtattg gtttatccca gttcataaac ttatgaagac caccagctct
     2161 ttttataagt tcatgacctg gtctcatata taaatggtat gtgttactaa gtattatttg
     2221 tgaaccaatc tcttttaatt cttctggtgt catagatttt acagttgctt gagttccaac
     2281 tggcatgaat attggtgttt caataatccc atgtggagtg tgtaatcttc ctaaccttgc
     2341 accactctgc ttacaagtct ttatcaattc atatcttact gcgtacataa agttctcctt
     2401 aaccatattt atttctcatt atttcttaag atatatttgt aataagctat tcatataatt
     2461 tattgtctaa atagatttat cttcgtcttc tttgttctgt tgctccttaa ttgcttcttc
     2521 atcatgaata ctcattatat taagagcact cttgtctttt gttactaaaa acttttttat
     2581 agcaaatagt cctgctatag ctataactcc tattaaaaca tctatcatac cttcattttt
     2641 aggcagtagc aacatttttc tagctattgc gtaaagtaat gcctcaataa atgctcctgg
     2701 tatatgaaga gatagcatta ctacaagttc aacacctatt actaaaagta atatttgtgc
     2761 taaaaaatca ttaagctgac tgtattgtac tggattttga aaatcaacta tatatgctcc
     2821 ccacataagt cttagaacat ctatagttcc taaaaatact gctattagaa ctactactgc
     2881 taaaacacgt tcaaatataa aagcaatctt taatataggg ttattctttt tttgtttttg
     2941 taaactatgc attcattacc tccctacttt ataatcatag catctccaaa actgaagaat
     3001 ctatatcttt cttttactgc ctcattatat gcatttaaaa cattatcctt tccacaaata
     3061 gcacttacta acattattag tgtagattct ggtaaatgaa aattagtaat aagtttatct
     3121 aaaactttaa atttataacc tggatatata aatatttctg tccatccact agtttctttc
     3181 atctttccat cctcattaca agctgattct atagttctac aactagtagt accaacacat
     3241 attacattgt ttccattttc cttcgctcta tttattttgt cagctgcttc ttggctaacc
     3301 atataatatt ctgaatgcat cttgtgattt aaaacatctt ctacttttac tggtctaaaa
     3361 gtgcctaaac caacgtgtag agttacaaaa gctatatcta cacctttttc ttttatttta
     3421 tttaacaatt cttctgtaaa atgtaatcct gctgtaggtg ctgctgctga accattatgc
     3481 tttgaataaa cagtctggta tctttctttt tcatctagtc tagcagtgat atatggaggt
     3541 agtggcatat ttccaagttc atccaatatt tcttcaaaaa ttccatcata aaggaatttt
     3601 ataattcttg aaccttcatc tgataaatct acaacttctc caattagctt tccatttcca
     3661 aaagaaaatt tagtccctac ttttgctctt tttcctggtt ttactaaagc ctgccaagta
     3721 tcttcctctg ttctttttaa taataaaaac tctattttac ctccagtttc aagcttctct
     3781 cctattaatc tagctggtat aactctagta ttatttaata ctaaacaatc tcctggattt
     3841 aaatattcta ttatatctct aaatacttta tgttcaatat tacctgtctc tttatctaat
     3901 accatcaatc ttgagctagc tctatcttct ataggaactt gagctataag ttcctgtggt
     3961 aagtcaaatt taaaatcact tgttttcaat gttaaacttc ctctcttaaa atttctccag
     4021 ctacaataat atcaaaaaaa caacttattt tccacaatat taccataatc tatcaagaaa
     4081 ttgctatttt taacagacac catatccaca atatatagat atttttccac gatatacatg
     4141 tcttatccac aatatataga tacaatacac acaattttta tcgtgtttat ccacagtatc
     4201 tacagatata attaccattt tgtggatata tttgaatttt tagccatttt agaaatattt
     4261 taatttaatg actcttttat tttataaata ctcgtataat ctatttttat ttttcattag
     4321 gatatggaat ttttaagtgt tcatatgcta atggcatggc tactcttcct ctaggacctc
     4381 tatttataaa tcctaattga agcaaatatg gctcatatac atcttctatt gtatttctat
     4441 cttctccaat agaagctgcc aatgtatcta aacccactgg tcctcctcta aatttttcta
     4501 ttatagtcat aagaagcttc tcatctacaa aatcgagacc caaactatcg actcctaaaa
     4561 gttccagagc atcttttgcc accttatcag ttatttttcc atcagctctg acttgtgcaa
     4621 aatctctaac tctttttagt aatctatttg ctatccttgg agtccctctt gaacgttttg
     4681 caagttctaa tgctccatta gactgtatct ctgcatctaa gatgcttgaa gacctaagta
     4741 ctatttttga aagttcatca actgtataat aatccaattt acaaataaca ccaaatctat
     4801 ctctaagtgg atttgtaagc ataccagctc ttgtagtagc tccaataagt gtaaatttag
     4861 gaaggtcaag tcttatgctt ctagcagatg gccctttccc tattattata tctaggcaaa
     4921 aatcctccat tgctggatat aaaacttctt caacacttct attgattcta tgaatctcat
     4981 ctataaataa aacatcattt tcatttaaat tcgtaagtat ggctgccaaa tctccagctc
     5041 tttctattgc gggtcctgac gtaattctta aatttacccc catctcattt gctattatac
     5101 ttgctagtgt agtttttcca agacctggtg gtccatataa aagcacatgg tctaactgct
     5161 catttctcga tttagctgct tctataaata tactaagttg ttctttggat ttttcttgac
     5221 ccaaataatc ttctaaagtt tttggtctta aactgttttc tatatctata tcttccatct
     5281 tcattgtaga agttattatc ctattttcat cttcaaaacc ttgcatttat acccctcctc
     5341 tcgtactttt gaaaatctac tttatatatt ttcaaattta cataaactcc ttaaatattg
     5401 ttttaaaatc caaatattat aaaatccaaa tactatttca aggatttact cattatatat
     5461 gtaagagctt tctttataat agcttctgta ttcataccat cttttttaca tttttgaact
     5521 gcctcttttg attccgacaa agtatagcct aaagctacaa gtgcatctac agactcatct
     5581 tgtgatatca aggtaggttt ttgtgataat aacgttggtt caaactctat gttatttttg
     5641 tctaccttat ccttaagctc taagacgatt ctttctgctg tctttttacc aacaccagga
     5701 gctttggata attttccaat gtcttcactt aaaatatatg ctcctaactg tgctgatgat
     5761 gcaaatgata gtattgaaag cgccacctta ggtcctattt tagatacaga tgttagtaat
     5821 tcaaacatct taagttcttc cctacttaca aaaccacaaa gactcatatc atcttctctt
     5881 acaattaatt tagtatatat ttttgtggct tctcccactt gtaaattcat tattgtattg
     5941 gatgatacat ttattttata tcctatccca ttattttcaa caactatact gtctatataa
     6001 atttcttcta ctgtaccttt tatataacta tacatactta ccacctatat tctttagagt
     6061 tttttcaagt ttgtttgaat gagcatggca aatagccaca gctaaagcat ctgcaacatc
     6121 atctggtttt ggaacttttt ttagacttaa aaatgaagtt accatctgtt gaacttgtgc
     6181 cttatctgct ctcccatatc caactacacc ttgttttact tgaagtggag tgtattcata
     6241 tacaggcttc ccattatgag cacatgcaag catagtaaca cctctagctt gtgcaactgt
     6301 tatagctgtt tttacattct tgttaaagaa taattcttcc attccaactt catctatatt
     6361 gtaattcttt actattgtat caattccttt atacacaagt tccaatcttc tcgatatatt
     6421 catatgggca ggtgttgtaa ctgctccata atcgattact ttaaacttgc tatttttgta
     6481 ttcaattata ccatatccaa ctatggctat acctgggtca atccccaata ttatcatttt
     6541 ttaaaattcc ccctaaaaat aaaagaaata ccaaaatgta tttctcataa aaacttatgt
     6601 tctaaatcat tatatcataa ataatattaa caaatcataa aatgctctat gtaaaatata
     6661 aaatcaaata aaaaagttat atcaaagcaa gattttacct caatataact tttatattta
     6721 ttacaaataa attattgtat ttttatagga attaaatgtg actacaattt taatactaat
     6781 ctatttaata ttaaattatt tattattaac ttacttagta tttaacttga aataatatta
     6841 atttactatt aacttgcaaa gtcttctaat cttgaatagg cctcttcttc agtatccata
     6901 actacacctt ttttgatttc atcttgaact gttttaggaa gtgaatctac tcttattttt
     6961 gttttttcta ctaatgtttt acttccacta tcatcatatt tatatagtgc tatatttcca
     7021 ttatcatttt caatagtata tttacctttt atagtagcgt tcattgcttg tacatcttta
     7081 ttatcactat atttagattc taccaatatg atttcatttt tatccatact ctttattttt
     7141 ttagttggat attctttttt aaaatatgat actatttctg attttgtctt atctaataat
     7201 gactctggaa ctatcccagc cattgtaagt gttctcttat agttagtttc attttcgcct
     7261 tcactttgaa gccaaacttc acaattttta tttaatccaa aagcttcttt tgacttttcg
     7321 tccatattcg cactagcact tacaacttta ctagtttgaa ctccattatt ttttaatctt
     7381 gtccctatat aaactccgct acttaataca aatactccaa ccagtattaa ggcagatatt
     7441 ttccaaggaa ataattcttt tttcttcttt tcaaacattg attacgcctc ctttttctat
     7501 tattttctcc aagctgtaag tttttataca atttaggtaa attttagaag aaaatatatt
     7561 tatatttcaa attactctaa gaatagatat tttctaaaag gtagttttct cttaatggtt
     7621 atattcttgt aattatatgg acataattta taataaataa tcgtttagga ggtaataact
     7681 ttggaaagaa taaactgtaa tgtaattaac tgttcacata acaacagcca tatatgttat
     7741 gcagataaaa tttttataaa tggtgaaaaa gctcacaatg acagacatac ttgttgtagt
     7801 tcatttttag atgaatctat ttatagtaat ttatctagca acgttaataa tagaaattgt
     7861 gaggaattag tttgtactgt aaaaaattgt aaatacaaca aagatggtag cttatgtaca
     7921 cttgataata tattggttgc tcctgaaact gatagagtaa acctttatat tgaaacatgt
     7981 tgttctagtt tcgaatgtaa atagtcatag tataaatata agggtgtcaa atgtaattaa
     8041 actaacatag tgtagagtat ctacaactat tagtttgatt atacttgaca cccttattta
     8101 ttttaaataa aatttcatta ttataaccat gtttataatg ttctaactgt aattaaattt
     8161 gataaatttc tataaattgg tataatcaat atgtaaattg aatttagcaa attaatcata
     8221 aaaataaaat atcgagtata tagtgttata ctaactagaa atgaggtgct tatgagtaca
     8281 ttttatattc aatttcttta ttttgtaatt tatagcttta taggatggtg ttgtgaaact
     8341 acatattgtt cagttttaca aaaacaattt gtaaatagag gttttttaaa tggtccattt
     8401 tgccctatat atggatttgg agcattagca atagttgcta ccttgactcc ttttgtacac
     8461 aatattcctt tgttattttt gtttagtata attataacta gcataatgga gtattgtacg
     8521 agctttattt tagaaaaaat atttaatatg acttggtggg attattctaa acataaattt
     8581 aatattcatg gaagagtttg tctggaaaac tcacttatgt ttggtgtatt atcattgatt
     8641 gtaatgctta tagtacatcc tattgtggtt gactttatta actctatctc taaaaatgtg
     8701 ctatttatat ttgctatatc tatagaaatt tattttgttt tagatttagt tatcacagtc
     8761 catacaattt tacaattaaa tggtaagtta aaacaaatca atcttataat taaggaatta
     8821 aaagataaga aagaatacta caaacttatt acacaagaaa ctatagaaaa caaacttgaa
     8881 tctttagttg aaaatagact ggatactttg gaagatagat ttgaaatact taaggaaaaa
     8941 gaaaactatc gctatgctaa aaatcgtatt gatgagctaa aaaataaact taatactttg
     9001 ctgtctaacc acaaattact tcatagacgt ataatcaaag cattccccaa cataagctct
     9061 aataagcata cagatatttt aaataaaatc aaagaaaata ttaaatcaat taaaaaagat
     9121 aaataataaa ataaacacat aagttaaata ataaaaatac taatacataa gattaaggtt
     9181 tagaatattt tttgtaaaat actctaaacc ctaattaata tactattatt tttaatctta
     9241 atttataatt ttagtttatt ttacttttaa cacagtaaat ttaagcgttt aaacttcaat
     9301 acactaatat actaccccat caatatctca actgattctc taagtgtgct aatctctccc
     9361 acatttccag ggaaaattat atatggcata ttaggaaatt tgctttcttt gcctgtcatc
     9421 catactggta taccaggttt tatctgtccc attactgtag ctttttttac tcttagtgct
     9481 ttagtaccaa catcactaga agtaattcca cccttagcta taataaaatt tggtcttaca
     9541 ttaagcatac caattatact ggtaactgca tctgatattt ctacagaaat cataagctgt
     9601 ttatctttat cattcgtatc caagtcaaaa cgctctcgtc tagtataaac agcaacagtt
     9661 ttaccactgc ttattttttc ctctacaact tttataactc tttttacctc attttttaga
     9721 ccattttcct gaagaactaa atgttgatta aattctataa attctattgg atatttacaa
     9781 tttttaagtt cttctaactg ttgggtagtc ttattcacat gtgaaccaac aagtataatt
     9841 cctccattgg tattaccttt tgatactaac tcatccttag taagcatttc cttatcactc
     9901 actccgccaa gtacttttgt tatggcagca gcgcttctaa acataaattc cttaccacta
     9961 tttactgctc gtataaacgc aattgtaaat acctttacat ctacataatc ggttgcattt
    10021 acaataattt tattgaatcc ttcagctttt ttaagttttt ctgttatagc ttcaatattt
    10081 agctctctaa gttctttaga agaaatatat atcatatcac tagatttgta ctttccatgt
    10141 gtcttttctt cacaccactc acctatatca gatgatttat atccaaaaga tttatccttt
    10201 gcaaattcag tcattcctgc tggtacaagt atttctcctt ctttaacata atgtacatta
    10261 tctatagtaa acctaccacc ttctttaaaa aatggcatta ttatttcacc ctgaaataac
    10321 ttccccgata atctctctac ttcgcttttt aataaattag tttcaacagg ataatgtcct
    10381 ctcatagtag aatcactacg acttatgatt ataaaatcct tattaacttt ctttgataca
    10441 tccacaatat tctttgaaat ttctttatgt gcttttgtag tttgagcaac agtaaatccc
    10501 cttgaattag taagtataaa aaacatacta tttttctcat taaaaccttg ttccatacta
    10561 tccttatccc aatcagtata aacagaaata tcatgaactg tttgtacacc tgttgggtca
    10621 tcatctaata caacaatttt tctatctaaa tgcttaagct catctgcaag aagttcattt
    10681 aatctgtcct catctacttg tttaaaagta ttaagtatat ctatgctaat tggttttact
    10741 tctctcattt aaaacgcccc tttatgtaat ttgtatagtc taaatgtaat ttatataata
    10801 taaacaatag tttgttattt atagacctgg aagtggtata attccattta taacactaag
    10861 caataaaacc attataaatg ctacaactcc agcaatggtt cctccaattg tccaagagtt
    10921 taaagtatct ttaactgata atccactaaa tcttgaaagt acccagaatc cagaatcatt
    10981 tggaagggag aaaccaactc ctccagcaca tatagcaagc cctactaaaa ctggtgacat
    11041 tccagttgcc aaaattgtag gtcctaaaat tgatgatgtt gttactaagg ctacagtagc
    11101 agaaccttga gaaattctaa gcaaagcact taataagaat ccaagcacta caactgatat
    11161 actaagacca gacatagtat caactaagaa gttacctata ccacttgcat ttataacact
    11221 gccaaacgca ccacctgaac ctgttatcaa taatattagc cctgctgaat cagcagcttc
    11281 aataactaca tctcccatag gtttatttat gtatctcttt aaaaatccta ttgccaccaa
    11341 tattccaaga agtattgcta tgtttttatc tcctataaat gcaagtactc cactcattgt
    11401 agaacctttt tctaagaaca tactaaatac atttgatata agtataagaa gtattgggaa
    11461 caataaagaa aacatagaaa ttccaaaacc tggtacttta gaagaatcat catcttcaat
    11521 ttttatgcta tcttttccct tttctaaatt tttttctcta tcattctcat caatagcata
    11581 agctggatat ttttcaaaac gttttccata aatccatcca cctataagaa ctgctggaaa
    11641 agcaacaatt atagaataaa gtataaaact acctacattt gcatttacat ttgctgcaac
    11701 tgctaaaggt cctggtgtag gtattacaag tgcatgacct actatagtcc caactcctaa
    11761 ggcacataca aaaaccatta gagatttctt agttactctc gaaacatact taattatagg
    11821 catcattata acaaaagctg catccataaa aactggaatt gaaattaaaa aacctgctgt
    11881 agttactgct aaagcactgt ttttttctcc agtcttagct aacaacccct ttgcaataga
    11941 ttctgttgct cttgattctg aaagaatatt tccaaatatt attccaagtc caattacaat
    12001 acctatacta cctaatgtat ttccaaatcc agtcgatatt gtggttgata tttcatttat
    12061 aggcattcta accataaagc ctgtaattat agatgttatc agtaatgcca aaaacggatt
    12121 tactttaaat ttaataatcg atacaagtaa aattcctata gatataacaa atgctatcaa
    12181 aagtccatat cctgtaatca taatctttac ccctttatca ttctacttta ttatttatca
    12241 attttatttt tcttttacta tgataactta acctcgctgt atttatataa tctaatccta
    12301 ataatatgta tttaattata ttgatatatt taaatattaa ttattgtgtt tttttatttc
    12361 aacacctgcc aacttttcaa aatactgtgc tattccacta tggtcatctt ccaaatgtcc
    12421 atgtactttt aatgtctgca taatttctaa taattgactt gtcataggta gcggtacatc
    12481 taaattgtgt gctgtttgca ttacattctt aatatctttc aaattaatag atatttttcc
    12541 acctggttta aaatcacgat tcataatcat tggtatcttc gcatccaata ttgtactacc
    12601 agctaggcct cctcttattg ccttatatac tttttctggg tctgcacctg cttttgctgc
    12661 aagtacaaat gcctcagaaa ctgctgctat cgtcaaatta actattactt ggtttgtaag
    12721 ttttgtaaca cttccactac cattatctcc aattaaaata gatgagcttc ccattatatt
    12781 aaaaaatggc tctactttct tataaatttc ttccttacca ccagccataa aagcaagtgt
    12841 accatcaatc gcttttggct cccctccact tactggtgag tctataaatt ctaagcccat
    12901 atcttttaat ttatttgcac acaatattga ttctgtagga gtaactgaac tcatatcgac
    12961 tactatactt ccttctttta aagtttttgc caatccatcc atcccaaata atatatcctg
    13021 aacaatagtt ccatttggaa ggattgtaaa tacaatatca cattcttgac ccatttctaa
    13081 aacacttgcg tattttgctc cacatgatat aagttcatcc acagcagatt tattaatgtc
    13141 atacaccaaa agattacatc catcttttaa taaatttttt gccattggct ttcccattat
    13201 tcctaatcca ataaatccca atttcatttt ataaccctcc atatcttcac atttttgaaa
    13261 acgtttttta tgttttagag tatactacat accagtatac cggtcaatat aaaatataaa
    13321 agtatttatt ttaacaataa atagtaattt ttaaagtcat ttattatatt tagtcatcct
    13381 atataagttt taatacatac tattgttttt aaatataata tgctactttt acagttttgt
    13441 atttttacta atttcaatta gttttaatta atctgccttt aatgttaatc atacttcaca
    13501 cttcaataat tttttatatt ttttaatctt atctgcaatt taaattgcaa aagattgacc
    13561 ttattttcac tatgttgtat gcttaaaatt atataagttt ttgtattttt atattgttta
    13621 ggggggtatt attaagtatg gctacattta aaagattaca agaacaagca tatgactact
    13681 taaaagaatt gatactatct ggagaaatga tagaaaatga aatatattct gaaacaaaac
    13741 ttgctagtga aataggtatc tctagaacac ctataagaga tgctcttcaa agacttagtc
    13801 aagatggatt tatagatata atcccaagca aaggatttag aatccatcaa attacagcaa
    13861 atgaaattgt agagatattc caaatacgct ctgcaataga agggttttgt acttttttaa
    13921 ttacaagtca atacaaagaa gctagggcag tagaaactat aagtaaatta aaacatcttt
    13981 tagataaaca aaaagatatt ttactaggtg ataaaaattt aaactcattt gcagaatacg
    14041 atacattatt tcacacaact atagtttcat atgctcaaaa tactgaattt gacaaaatgt
    14101 ttaacaacta tatgtacaga ataaaaaaat tagctctcga ttcattatca catgaaggaa
    14161 ggcttgaaac aacattaaaa gaacacacag atatttttaa taatattgca aatggatgta
    14221 ttgaagatgt ttacaaaact actctcattc atatggaaac tcctaaatac attaatttag
    14281 aagatttttg taacaataag tgattttagt attatacttt catttattaa aaatatatct
    14341 acctcaaatt aatttcctaa tttataaaaa atattctata attatattgt aactaatact
    14401 attctaagga gtgatttttt tgaacgaaaa tgttgtaact aatgaaacta ttgacaaaga
    14461 ttatgctatt gaagaagttc gtatggcatg caaacatttt ggtgacttat atttttattt
    14521 ttccaaagtg ttatttgaag agtttggtga agataaaact atcgaaatac taagaaaagt
    14581 tttatttgaa aggtctgaag aaagagctat tgctatgaga gaaagagctc ttgaaaatgg
    14641 agatgaatta attgcagaca atattattag cacaactgat gttccatttc taggatgggt
    14701 tcctgaattt aaagagttac attgccctta tggagcttcc tggcttttaa gatttgagga
    14761 aaacccttgg tttaaaaaat tcgcttctct ttactgtgat gttacagata ctactgtagc
    14821 tgaagtattt acaggagata cgtcccataa aataacaaaa aacattctat ggggagataa
    14881 aagttgtgaa agaatatatt tccatgatga caaggtatct gaaggtaaat atacttatgg
    14941 aaataaaaac tgtaaataaa taatttaaat tttctatatt catatactat attttgtact
    15001 ttttcatata aatattataa ctagtctttt attttacttt tgtttaacct aaagataatt
    15061 tacttttaat ctatatgaat tatcatataa ataatcagaa agttatcttt ataaattata
    15121 gttttagatt tataatttat aaaatattta tgttctttgt aaaatttttt agaagcttct
    15181 aatgttatgc tataaaacta tcttgagaag ggctgattga atgtttaata aaatatatga
    15241 aaagaaagaa tttatagttt ttcaagttaa aaaaggttat gtagtttata atactagaaa
    15301 gagttttgaa gaaggtcata cacatttaaa gcattttgaa gcagcaaaga cagctattga
    15361 tttagcaata aataaaaaga ttcctagaag caaagatgga tattatctga ctagtttaat
    15421 tcgcataagt gatgatggtt attacattga taagttaagc gaattgttat atgttagaga
    15481 acaaaaaggt aaaaaagaaa agtactgtaa ttctggttat cagatgtaac aagactagtt
    15541 gtgaattata agtaccaatc ataaatacct ttagtcttaa aatcaaagag tatcagtaaa
    15601 tctataaaaa aacaacttac tgatactctt tttaattata tgattaatat ttgaatttga
    15661 tacaaaattt tatacaaaag tttatgttat ctattctgat tctttgtctg caaattggct
    15721 attataaagc ttctcataaa atccaccctt ttccattaat tcatcatgat tcccctgctc
    15781 tataatactt ccattattca taactaaaat caagtcagca ttgcgaattg tagaaagtct
    15841 atgtgctata acaaaactag ttctaccatt cataagattt ctcattgctt tttgaagcat
    15901 aagttccagc ctagtatcaa cagaactagt agcttcatca agtatcaata ttgaagggtc
    15961 tgatataaaa gctctagcta tggttaaaag ctgtttttcc cctagagata tattagatgc
    16021 ttcttcattt aagaacatat tgtatccatc tggaagagtg gttataaagt gatgaacatt
    16081 tgctactttt gctgcttgta taatttcttc tttagtagct ccaaatctac catattctat
    16141 attttcaaaa atggttccat taaataacca tgtatcttga agcaccatac caaacattga
    16201 acgcaaatct ttacgtttca tatctcttat atctactcca tcaattttaa tagcaccttt
    16261 ctttacatca taaaacctca tcaataagtt tattaatgtt gttttacctg ctccagtagg
    16321 tccaacaata gctaccatct gaccactttt tacttctgca tttaaatctt ctattaaagt
    16381 tgaattttct ccatatccaa aattaacatg ctcaaatgta acatttcctt ttacattttc
    16441 tatcttaact ggattttcaa catcaggtat ttcctcttct tcgtctaaaa tttcaaatac
    16501 acgttctata gctgcaaaag aagattgtat tactgtagat aactgagtca tttgtgaaag
    16561 tggctgattt atctgccata tataacgcac aaatgcttgt aaatttccta ctgttatccc
    16621 tccacttact gcatatatag aaccgacaac tgccacagct gcaattccaa agtaagttac
    16681 taatgaaacc ataggattca tcatacttga tataaattgt gccttaaatc cattttcaca
    16741 aagttcttga tttacttttt taaattcttt tatagaatct tcttctttac catatagttt
    16801 tatttcatta aatccagtat acatttcttg tacttttcca tttaattttc caagagcatt
    16861 ttgttgcaat gaaaatctac tttgagattt ttttactaca aatttagata caaaataact
    16921 aattggaatt ataaaaagag ctataagagc catatatata ttaattgtaa acatcattga
    16981 aagtgccaaa attatgacta agattgagtt tacaatttgc ataaaactct gttgcaatgc
    17041 atttgatatt gtatctacat catttgatat acgacttaat acatctccaa aactattact
    17101 atcaaaataa ctaataggca atcttcttat tttattttcg acttcatttc ttaaatctct
    17161 cattgtgttt tgaatagcat tcgtaagtag aaaacttgaa gtatacgtaa aaattgcatt
    17221 agcaaaatat atacatgcta aaatcaccaa tatttttgtt acataatcaa aatttacgga
    17281 agcccctggt actccttttg cgatactaat tacatcttta gtcaattgtg ttattatcaa
    17341 tccttcagtt ttaggtgcaa gtgcattcat agtagctgct gaaattatac atataatagc
    17401 tataataaag gaaaatttat atttctttac aaatggaaga agtctaccaa ttgttttctt
    17461 aaaaccttta gactttttca ttattctaat tcctcctttt ttaactgaga tgttgcaatt
    17521 tcatagtata tttcacagtt ttttaataat tctttatgag ttcccattcc gacaacttgt
    17581 ccttcattga gtactataat cttatcagca tcaataatag aactaattct ctgggcaaca
    17641 atcaatacaa ttgcatcttt tgtttccttc ttcaatttag cacgaagtat tgcatccgtt
    17701 ttaaagtcaa gtgcagaaaa actatcatca aaaatgtata tttcaggtct tcttataata
    17761 gcccttgcaa tagaaagtct ttgtttttga cctcctgata catttgctcc accttcacta
    17821 atcaattcat caaactttct aggttttttt gatataaact catatgcttg tgcaactctt
    17881 gcggaatatt ctaattctga ctctcctgcc ttatgtttcc caaatctaat attatttgct
    17941 atgctaccag taaaaagcag tgatttttga ggtatgaatc ctatcttttt tcttaaagct
    18001 tttaaatcat attctcttat atctactcca tttatcttaa tgctaccctc tgttacatcg
    18061 taaaatctag gtatcaagtt aattagagta cttttcccac taccagtact tcctataaaa
    18121 gcgactgttt cacctgtttt tgcagtaaat gaaatatcct taagtacaga agcttctcca
    18181 tctggatagg taaaagttac attatcaaat tctatgatac ccttattttc agtatcctta
    18241 attccatttt caggattttt tatcaatggt tcttcattta aaagttcttt tattctattt
    18301 gcagatacct ctgctcttgg atacataata aataccattg aaaaaagcat aattgaaaac
    18361 atggcatgga aaagatattc caaaaatgca accaactgtc caacttgaag ctctccaata
    18421 tttatcttct cacttgaaat ccaaaataca gccaaaacag ctatatttaa tagtaaaaag
    18481 aatgctggtt gagtaattga cataagctta aatagtttct tagaaacatt agcataatat
    18541 gtatttgttt tttcaaatcg ctctgtttca taatcatcat ttccaaaagc tctaattact
    18601 cttattccag ttaaattttc tctcgatata aggtttaatt tatctagtcc tttttgttgt
    18661 tttgaagata ttgcctgaga tacttttgct attattgcta ctccaataat tataaaaggt
    18721 actgatatag ccaatactat agaaagttcc acacttgttc taattgtcat tattatactt
    18781 atgatgaaca taactggagt taataaggca gtccttagta gtatattaac aaattgttga
    18841 atttgaaatg catcattcgt tgttcttgta atcattgaag aaattccaaa tttattgtat
    18901 tcagtatgtg aaaattcttg tgatttctca aatatgtcat ttcttatatc tctggttaca
    18961 cttgttgata ccttagcaga acaataaccc aacaatatac tacctacaac ccctataata
    19021 gaaataataa caatcactat tcccatttgt tttatgtaag ctatattctg atttgcaata
    19081 ccattgtcaa ttattttagc tattatagtt ggaatcccca actcgactaa tgcaaaacta
    19141 aatatagcca gtatgtttaa tactattaat aacttataat tctttaaata acttaaaatt
    19201 aatttcatat ttttctcctt tcttaatttt tgagatagtg taatcatgta ataatactaa
    19261 atttataaat gcttaatttt ataaaaaaag gagaaaagag ttaacgcact ctcttctcca
    19321 gcatattctt tttaatacac cctccgacaa gtcgcttata tgttaacata tttgacaagt
    19381 aatgtcaatt catatagcta aaagtctttt aaatgcttca tctcataaca ttgtaacaaa
    19441 ttggcatgta atttattttt gttttttact gtattccaat tttacaagtt ctccaatatt
    19501 actaactttc ttaaaattca aattagtctt atctatacca gacttaaata gtgaaatccc
    19561 tctccccaat attattggca atatatatat ataataatca tcaattaagt tatctttcat
    19621 aaataatttt actatatcgc ctccaccaac tatccaaata tcttttttat ccttcttttt
    19681 tccaatttgc tcaattaatt ttttaggttc taaattagta tactttacat tctccagttg
    19741 tcccattaat tgtatttgag tatatatagc attccttacc cttatagtac cattcatttg
    19801 ggcttaattc atttgcaatc tgtacatatg tggaatttcc cataatgata gtatcaattg
    19861 tatcgtaaaa agtattataa tcatcttcct gctcattctt aaattctgaa gatatctcgt
    19921 ctaaaaaact tacactgcca ttctcttcag ctatataacc atctaaactt gtggcaatat
    19981 aaagtactac ttttctcatg tttactacct ccaacattta tagtgtgatt attctatgta
    20041 aacatcactt ttttactcat tcaataatac cctattaata aatcctcaaa ctaatttaaa
    20101 taaactttgc ataaaactaa aaatatatta tataaataat ttaaaatcac actaacttat
    20161 tgaaaattct aattattaca aataaatatt gctctctgtt aacgctagtt ttataatata
    20221 attataagct attaatatta taaagccgat attactaata taataattat agttaattta
    20281 cttttgttga aaggtggtaa ataacatgaa aatttcagaa gtcgctactc caaatttttt
    20341 gctagattta gaccagttag aaaagaatat agataaaatt caacaaattt gtacaaataa
    20401 taataaacaa ctttggccta tgcttaagac acataaaagt acttacatag cgagacttca
    20461 aaaaaatgca ggtgctagtg gttttctagt tggaacactt gatgaaggtg aagctctgat
    20521 aaaagcaggt tttgaagata ttatgttggc ttatccttac atgggagaag taaatataaa
    20581 tagaattgtg actatggcat caaaaataaa tttaatctgt gctacagata atatagaatg
    20641 tgctaaggct tatagtgaag ctttttctaa atcaaaaata gagtgcaagc tacttattat
    20701 tgtagattgt ggcttacacc gttttggggt tgaaccagaa aaagtggttg aacttgctac
    20761 tgaaatttct aagctagaaa acatcaagat tgttggtata agttcgcatc caggtcaagt
    20821 gtacggttgt agttctccag aaggtgttcc agatgtttgt gttcaagaag attcttctat
    20881 ggagaaagca tacaaagctc taactgataa tggatttaat atagaaattg tcgcttctgg
    20941 tagtactcca acagttgaag ctgaagctgc ttctaaaact ataactgctg taagacctgg
    21001 aaactatgta tactatgatg ctatacagat aggtttaggt tgtgctactg aagatatgtg
    21061 tgctcttact gttgtgtgta ctgtaatctc aaaaaatagc agtggatatt atttaattga
    21121 ttgtggaagt aagtgccttg gacttgataa aggtgcacat ggaaatagta gtattgttgg
    21181 ttatggtagg gtatgtggac atccagaact tactattgat tcactttcag aagaagttgg
    21241 aaaaattaaa gtaaatggtg aaactgatat aaaaattggt gatagaataa gaattatacc
    21301 taatcattct tgttccactg caaacttgac gagtaattta ttaggtttta gaggagatac
    21361 aatagaaaaa gtcatagaag tagatattcg tgaaaattca aaacaaatca tcctttaaaa
    21421 atatatttat tttgatatta acatcatgaa agtatatttt tcttaaaatt attgttaata
    21481 actaatgtta atgttggata aataaaaaac ataaattcta gaaatataaa tttaaaaaaa
    21541 gaggctgtct caaaattgga tatgtccctg tcaagtagac agacttaaaa aaggctatct
    21601 ttatgcggaa tgagttcgat attcaatcgg actcattcca ttttttaatt gtattctttc
    21661 attattataa aaataaatat aatcatttat tagactaatc atttcctttg gatctgtagt
    21721 atcaattaaa tatattaatt cagatttaaa atgactgaaa aaactttcta taggagcatt
    21781 atcccagcag ttgccccttc gggacataga ttgtataata ccattatctt taagcctttt
    21841 agagtaagat ctacttgtat attgtgaacc ttgatctgta tgtaaaatac aatctttagc
    21901 taaattcata tttattagtt gatttactgt tttattaact aatttagtat ccatttttgt
    21961 acttatctca tatgccacta tttcaccatt aaataaatct ttggctacat t
//
LOCUS       DAMJWO010000072        21955 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.073, whole genome shotgun sequence.
ACCESSION   DAMJWO010000072 DAMJWO010000000
VERSION     DAMJWO010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21955
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.073"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(193..900)
                     /locus_tag="PC366_002775"
     CDS             complement(193..900)
                     /locus_tag="PC366_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDF2578272.1"
                     /translation="MMNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAEPTNSPMS
                     ATVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKSVDNVTGWVNGDY
                     LTIQGGNVDAKVQNVLNLAFKQQGKPYRWGATGPNAFDCSGFTSYVYKNGAGVNLPRV
                     SRSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGDSKFIHSPQTGDVVKVTSMA
                     PGTNYARRLITATRVLQ"
     gene            complement(1099..3012)
                     /locus_tag="PC366_002776"
     CDS             complement(1099..3012)
                     /locus_tag="PC366_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDF2578273.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNAFTTNDIIISVCIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFVATLAYLI
                     PIYIINKLLGFDYPIMFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKVSNILII
                     GAGDAGEMVIQELKRNSELKKVAVAIIDDDKDKIGRIIHNVKIVGTTSDIKAVVEKYN
                     VDEIIFSIANIEKRRKKEIIDICKNTNCKIKTIPGIYEIIDGKVDIKQIREVEIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            complement(3096..4187)
                     /locus_tag="PC366_002777"
     CDS             complement(3096..4187)
                     /locus_tag="PC366_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2578274.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSIKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLAKELGIENDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKNAIIKLMENDELRLNMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            complement(4193..5536)
                     /locus_tag="PC366_002778"
     CDS             complement(4193..5536)
                     /locus_tag="PC366_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HDF2578275.1"
                     /translation="MPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLAEVGNENVV
                     CVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDVDVILIAVG
                     TPERSDGSANLDYIKAVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYINRNLKNNVK
                     VELASNPEFLSQGTAVKDTLYASRIVIGVESEWAREILEEIYKPFNQPIIVTNRNSAE
                     MIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLKAGIGYGGS
                     CFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQDMKVAVLGL
                     TFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYADSVDDAIE
                     DAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKIKDMEELGIEYYSIGR"
     gene            complement(5514..6266)
                     /locus_tag="PC366_002779"
     CDS             complement(5514..6266)
                     /locus_tag="PC366_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2578276.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENVGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            complement(6314..7222)
                     /locus_tag="PC366_002780"
     CDS             complement(6314..7222)
                     /locus_tag="PC366_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2578277.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALRGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            complement(7244..7993)
                     /locus_tag="PC366_002781"
     CDS             complement(7244..7993)
                     /locus_tag="PC366_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2578278.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYKRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            complement(8022..9197)
                     /locus_tag="PC366_002782"
     CDS             complement(8022..9197)
                     /locus_tag="PC366_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HDF2578279.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHKFNGRDIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            complement(9212..10051)
                     /locus_tag="PC366_002783"
     CDS             complement(9212..10051)
                     /locus_tag="PC366_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2578280.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNEDYKIYSCKTMDSNKVDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGNDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYTFAKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            complement(10054..11211)
                     /locus_tag="PC366_002784"
     CDS             complement(10054..11211)
                     /locus_tag="PC366_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HDF2578281.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNIDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRIILFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLPIILTLFSVIIGTIFDKSTLLNRLLASRPKFWHVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            complement(11227..11949)
                     /locus_tag="PC366_002785"
     CDS             complement(11227..11949)
                     /locus_tag="PC366_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDF2578282.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIKVLYEQGGVYMDTDMQILKDITPLLENNR
                     LICGYEDDREYINGAIIGVEKGHPFLKDLLEYYEKEVLTSSLFTIPKIMTHLMEKNYK
                     KIDPNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTFGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            complement(11961..13034)
                     /locus_tag="PC366_002786"
     CDS             complement(11961..13034)
                     /locus_tag="PC366_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HDF2578283.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDSNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKDEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEYISKYLGTKEEMEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            complement(13056..14762)
                     /locus_tag="PC366_002787"
     CDS             complement(13056..14762)
                     /locus_tag="PC366_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDF2578284.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKNLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIMKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDMANDIIAEVNKIDDYSTIKSIDFEEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDEYGKKLKIIYTPIHGTGNKPVRKVLNECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKNNDTDLIIGTDPDCDRVGIVVKDSSGEYVVLNGNQVGSL
                     LVRYILESLVEENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEESNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALID
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKDGVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            complement(14804..16363)
                     /gene="murJ"
                     /locus_tag="PC366_002788"
     CDS             complement(14804..16363)
                     /gene="murJ"
                     /locus_tag="PC366_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HDF2578285.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGDGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDDKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVATLLIYNNLYAFMGSGTIKEIISVGAGVLGGASVYTVLIVLFKVEEMDLAFEFL
                     RKGKQKLLRRR"
     gene            complement(16478..17533)
                     /locus_tag="PC366_002789"
     CDS             complement(16478..17533)
                     /locus_tag="PC366_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HDF2578286.1"
                     /translation="MIKKISTILSLVLLISISSTIEVFADANPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEESIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGIKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTAKLDFGSRSDVNEYISLGVV
                     SAKENMPILICSDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFKSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            complement(17628..18314)
                     /locus_tag="PC366_002790"
     CDS             complement(17628..18314)
                     /locus_tag="PC366_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HDF2578287.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            complement(18534..20558)
                     /locus_tag="PC366_002791"
     CDS             complement(18534..20558)
                     /locus_tag="PC366_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2578288.1"
                     /translation="MKKTTKLLATGMLSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGATRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNVTRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQG
                     TYNWLSSQGLEEAYYIGGSQSLSSKIIDQISKIAKNGTSKNRVSGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHSTNLSEKTAGT
                     VYQIGDGMKDSVINSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGAGNGVEIYYKVKDKNGGTTKTAASNILKRILEKFNMKNRGIKTRTLDNGKDY
                     LYVLRNNNYPAILVECAFIDNKSDMDKLNTAEKVKTMGTQIGIGIEDTVK"
     gene            complement(20812..21870)
                     /locus_tag="PC366_002792"
     CDS             complement(20812..21870)
                     /locus_tag="PC366_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5009 domain-containing protein"
                     /protein_id="HDF2578289.1"
                     /translation="MIVCNNPGTWMRMYPQLRHAVWHGVTLADFAFPFFVISLGVTIP
                     ISINSKLKNNKSTLSIILSIFKRSILLILFGFFLNYLGNPDLNSVRILGVLQRMGLVY
                     FVTSLVYLLLKKLNVGSTATIITFLCIATFIIVGYYILAKPYGFELEGSLAQLVDLHF
                     FKGHLYKPEFEPDGFLTSIVAISSGMLGCTMGCVLLKENIGEYKKFFKILVMSIILLI
                     GAFIFNQYFPFNKRLWSSSFVLLMAGSYGMLLSIFYFICDIKNKSKIFTPIIALGSSP
                     IFTYMCLEILSHVFWNVPKLTNKVDYPTTLVEWTTYELITPWAGTTWDSLIFSLLYVL
                     FWVIVMSIMYKKKIFIKI"
BASE COUNT         6849 a         4055 c         2292 g         8759 t
ORIGIN      
        1 tatttgatat ttgattataa tatgaaataa tttattataa aaaaaacagc aaagaaattt
       61 atcttctttg ctgtttttat aacgttcatc actattttaa tattactaaa ctcttaaatc
      121 tctatgtaaa acattaaatg taattatata tttaatgtta atattcaatc ctatgtaaat
      181 caatatctat tattattgta aaacacgtgt agcagttata agtcttcttg cataattagt
      241 tcctggagcc atgctagtaa cttttactac atctcctgtt tgtggtgaat gtatgaattt
      301 agaatctcct acatacaatc caacatgatt tattgaacca cctgaaccaa agaaaactaa
      361 atctcctggt tttaattctg ctcttgatac tttctttcct actgttgctt gtgatcttga
      421 tactcttggt aaattaaccc ctgctccatt tttatagaca taagaagtga acccagaaca
      481 atcaaaagca tttggtccag ttgctcccca tctatatggc ttaccttgtt gcttaaatgc
      541 taagtttaaa acattttgta cctttgcatc tacatttcca ccttgaatag ttaaataatc
      601 tccatttacc catcctgtaa cattgtcaac actttttatt ttaatccatc catttgaatg
      661 taattctaaa acttcaactt tgtctcctgt gtttatcttt cctactactg catcatttgc
      721 actagctcca cttcttacat ttaaaaaatc acactggtct actgttgcac tcataggtga
      781 attagttggc tctgctgcac tagccgttat tgctcctgct tctactgtga caactcctgc
      841 tattaacacc atagctataa attttttcaa tatatgtttt ttatttttaa tattcatcat
      901 aatctcaaat acctaatcct ttcgaaaatt taacattttg ttccttcgtt tccaattcct
      961 aattaacatt ctatcttaca tcaaaataaa ttgcaacctt ttttgtaatc tttttgtaat
     1021 ctttttgtaa tcttttgttt ctttttagta tatatttgtt tctttttgct ccccctggtt
     1081 acaaattaga aatatattct acttttctct agttgttgca atttctttga tattagcatc
     1141 ttctggttta atataagttg gcactaattc cctcataata ccatctattt tttcaacctc
     1201 ttcattgtta gtaatttctc ttaaaagttt taagtatttt gttatttttt ctctatcaac
     1261 atctattggt ctaccaataa aaatcttttt atgctctgta tccaacagac cttcttctga
     1321 cataagtagt tcttcataca acttttctcc tggtctaaga ccagaaaatt caatttttat
     1381 atcaacatct ggctcaaatc cactgaattt aattaagttt tttgctaaat ccaatattct
     1441 tacaggttct cccatatcaa gcacaaatat ttctccacct ttagccatag ccccagcttg
     1501 tataactaag cctactgctt ctggtattgt cataaaatat ctaatgatat ctggatgagt
     1561 aactgtcact ggtccgccat cttcaatttg cttcttaaaa agtggaatta cactaccatt
     1621 actaccaagc acatttccaa atctaacagc aacaaattca gtctggcttt cagcattcat
     1681 agtctgtata atcatttcag cagctctttt agtagctccc attatgttag tagggtttac
     1741 agccttatct gtagatataa ggacaaattt cttagctcta tattttgaag acaagccagc
     1801 tatgtttaaa gttccaaata tattattctt tatagcttcg ccagggctcg attccataag
     1861 aggaacatgt ttatgtgctg ctgcatgaaa taccacttct ggtttatatt tattaaatat
     1921 ttcatccatt cttttttctt ctcttattga tgctattact gtctttaaat ctaatttatt
     1981 tttatatttt ctaagtaatt cttgttgtat tgagtaagca ttattttcat aattatcaac
     2041 tataataagc tctttaggat taaatcctgc aatctgtctg caaagctctg aaccaattga
     2101 gcctcctcct ccagttatta ggattacttt tccctcaatg taattactta tctctcttaa
     2161 atttgttttt ataggctctc tacccaacaa gtcttctatc tctacttctc taatctgttt
     2221 tatatcaact tttccatcta taatttcgta aattcctggt attgtcttta ttttacagtt
     2281 agtgttttta catatatcaa taatctcttt ttttctacgt ttctctatgt ttgctattga
     2341 aaagattatc tcatctacat tgtacttttc taccacagct tttatatccg aagttgttcc
     2401 tacaattttc acattatgga ttattcttcc aattttatct ttatcatcat caattatagc
     2461 cactgctact tttttaagtt ctgaatttct ttttagttcc tgtataacca tttctcctgc
     2521 atctcctgca ccaattataa ggatatttga aacctttcct ctagaatatg tcttgttcat
     2581 gactattctt atagctctat aagctattct tgcgccactt gtaaacatta taataaatat
     2641 tgtatttaat acataaaaca ttataggata atcaaaccct aataatttat ttattatata
     2701 aatcggaatt aaataagcta aagttgccac aaaaatagat ataatttctt cttctcctgc
     2761 atatctccat aatgtgttgt agcacttaaa caatctaaat gatactatat gaagtactat
     2821 atatatacac actgaaatta ttatatcatt agtggtaaat gcatttaaat tacctgtcaa
     2881 gcttaaagac attcgaaacg ctactagtac gctacaaata tctagaatta atagtgttaa
     2941 atgtctaaat ttatattttt taaaaagcct attaaaaaag ctttctttct ctaaatctat
     3001 actttctcgc ataactagaa gccctccttt aaacagcaaa agctacgcac ctaagcatag
     3061 ccaacaacat ctatcttttg ctgtattttt tcattttatt ttttatattt atcaaatata
     3121 gaatcataaa ttttttctat atcattaaag tttaaattaa cctcataatt ttctctaaca
     3181 aattgacgcc ctttcttacc catattaagt ctaagttcat cattttccat tagttttatt
     3241 atagcatttt ttatttcttc tggttgtttt ggttctacaa ttaagccagt ttcattttcc
     3301 catacagatt ctggatgtcc tcctacattt gtaactataa caggtacttc acatgcttct
     3361 gattctatag ctgccactcc aaatccctct cttaaagaag gaaatacagt tacatcaaaa
     3421 gaattaaaag tcttgcttac attttctgga gatattcttc ctaaaaactg aacatcattt
     3481 tctataccca attctttagc taaatttatt aggttgtcca tctgacttcc agagccacct
     3541 attttaagaa ttattttctt atctttatat tcatctttaa gcatcttaaa tgcttgtatt
     3601 aaatattcta ttccatattt tttttctaaa ctctttataa ttcctattac aaaagcgtct
     3661 tctttttcta cttccatagg cttaaaccta tccatatcta ctccaaaaaa ggttacatct
     3721 acatgtttag ctgtatattt attagcctct ttagccatat ctctactatt tgaaaagata
     3781 tagtctgctt ttctaaagtt atgttttata atttgttttt gtataaaacc attattaggg
     3841 aaatcataaa tatcagtacc ccaaacagaa ataatatatg gatgataccc aagtagactt
     3901 cctataaatc cataactact tgcatactgt gcatgcaata tatctggctt tatttcattt
     3961 actagcttct ttatctgctt tattgaacct aagtatcccg tttttttaga aatattttca
     4021 ttttttaatt cttctacatt agaaccaaaa ttataaattt ttattccttc catgtgacct
     4081 ccatttaaag agattacatg aatgtcatat cctttatttt taaaaaaact acaccatttt
     4141 aaagtatgag gatttgaccc atcagctaaa taacaaacag tcttcataat atttaccttc
     4201 ctatcgaata atactcaatt cctaactctt ccatatcttt aattttataa caatttcttc
     4261 catcaaggac taaaggattt ttcatctttt ccttatactt atgtatatca taatttaata
     4321 catctttcca ttctgtcatt ataaaacata tctctgcatc ttctatcgca tcatctacag
     4381 aatcagcata aagtatagag tcaccaaata ttttcttagt attatttaca ccaattgggt
     4441 cgtatacagt aactcttgcc cctctttcaa gcaaatattt tatatttggt atagatggtg
     4501 cttctcttat atcatcagtg tctggtttaa aagtcaaacc taaaacagca actttcatat
     4561 cttgaaagct ctctactaac ttagatgcct ttctaactaa tttaagtttt tgactttcat
     4621 taacttctat tgcagctttt actgttttta attcataacc attatgttca gataaccagt
     4681 gaagagcttt tgtgtctttt ggaaagcaag aaccgccata ccctattccc gcctttaaaa
     4741 acttacttcc tattctatca tcataactca ttcctaaagc tacatcttct atgttagctc
     4801 ctgctatttc acaaagattt gcaatatcat tcataaatga tattttaaga gctaagaagt
     4861 tatttgatgc gtattttatc atctcagcac tatttctatt tgtaactatt ataggttgat
     4921 taaaaggctt atagatttct tctaatattt ctctagccca ttcactttct acacctataa
     4981 cgattcttga agcatataga gtatctttta ctgctgttcc ttgtgataaa aactctggat
     5041 tagatgcaag ctctactttt acattatttt ttaggtttct atttatataa tcttctatct
     5101 cttcatttgt accaattgga actgtagatt ttattactac tagagtatct tttgtcacag
     5161 tttcagctat ttgctttgca actgccttta tataatctag gttggctgag ccatcacttc
     5221 tctcaggtgt acctacagct attaatatta catctacatc ttcataagct tttttatagt
     5281 ctgtagtgta atctattctt cctctgttgt aatttttaac cataagttct tctaggcctt
     5341 cttcatatat aggtgctatt ccaagtttca ttgatttaac tttttgttca tctacatcaa
     5401 cacagactac attttcattg cctacctctg ctagacaaac acctgtaacc aaacctacat
     5461 atcccgtccc agctatagct attttcattt ttttacctcc aagtatataa aacttatact
     5521 ctttttttaa tggcattaaa aacatagaaa caaaatacat atagactttt tggtaaactt
     5581 aaattttcaa catttctata agtattccaa gttcgtttta atgcttttat cttgttactt
     5641 gatatagaat ttccaactaa tctgtaattc actaaatcct cctgaatccc atatgcatat
     5701 ttttcctttt taagtaactg taaccaggtc gcagtatctt gtcctcttct taccaaaggc
     5761 atgctgaact ctcctacaat ctccttatca atgaccactg tagaacatcc tattatagta
     5821 tttctaagta atccttcata gtcaattttc ttaggagctc ttgcaacctt attcgttttt
     5881 gacccatctt gtctcatata tctataagat gtaaaagaaa aacctacatt ttcttttaac
     5941 atatattcta tctgaatctc taattttcta ctatcccata aatcatcact atctacaaat
     6001 gcaataaatc gaccttccgc attcttaata ccaacatttc tagatactgc agctccagaa
     6061 tttttttcaa gctttatata ttttattcta gcatcttctt ttcgaaaact ttttataatt
     6121 tcacttgaat tgtccttaga acaatcatcc actaataaaa gctgccaatt tttataagtt
     6181 tgattttgga ttgactttat cgtctctgat aaaaactctt ctgaattata aacaggagta
     6241 attatcgata ctaaaggctc attcatattt ttactctcct tatatagcaa ctagcagtac
     6301 tataccaaca agtttactta gatactaatt ttctttgtcc aatatatttg taatatccta
     6361 atgggaataa tgctaaatac aacaatttat cagatacttt tcttaattca ccaaaataat
     6421 gactatcaga caacaatgag tatctggcta aatttatgta attttttatc cacatatatg
     6481 gatatctact taatggatat gtattttgat ttattaaata taaaaactct aatgctctac
     6541 ctcttaatgc atttttactt aatatattct tagtcaaacc atcatccaaa taatctctta
     6601 ttatcatagg tttatttaca catataactt tatagtattt agacatttca ttccatacta
     6661 cactttctgg taaaaatctc acttcttttc tttctggaaa aggaaatttt ataagctcat
     6721 cagttacaaa tactatgctt ttatctccct taacgccata cttaaaatat aggtctgcaa
     6781 agtgacatat tttcttatct tcaggcattt ctgtccctat caaatctcca cttggatata
     6841 cacaaagtcc aacaactcca ctaaatcctt ctttattctc taaagaatcc cactcatcat
     6901 tagcaatttc aagagaatct ttaattaaac catcatcact atctacaatg aaaaatagct
     6961 ctccatctgc attttttaca cctagattta ttgcagtatg ttttcctcca ttttctttgt
     7021 atatatatct tatatttaat ttattttctg atataaattt ttcaactaac tctttagtac
     7081 tgtcgctact tccatcatca acaatcaacc attcaaaatc attgaaatca taagtttgag
     7141 cttttaaatc attgtacaaa ttttcaagta aatgagctct gttatacgtc ggagtaaata
     7201 cagtaaattt atatttatac attaattaaa tcttcctctc tgtctaactt tttttgattc
     7261 cgtttattcc ataattaata aagtagtata tagctttgta taaaggtatt ttttctatat
     7321 ttctatatat attccaagtc cacatagcag cttttatttt attaccactt agggaattgc
     7381 tagattttct atataatgct agaacttcat ttattccatg agcaatatgc ccttttttca
     7441 atatcgataa ccataaaaca tagtcttcat gtcttacacc actcattctt atttcaaaat
     7501 ccaatttaga cttatcaatc acaacagtaa gacatcctaa gatatttcct tttaataatc
     7561 ttttataatc tacattaggt ggaactttta ttactttgtt taatttttta tcattttcat
     7621 ccatcagttc atatgaagta aatgaaatta catagtcatt ttctaacata aaatttactt
     7681 gtttttctaa cttactgcta ttccattggt catcactatc taaaaaagct ataaattgtc
     7741 ctgttgcctt acttagtgct aaatttctag cattagagac acccttatta gtctcagtct
     7801 ttatacattt tattctacta tcctgttgca tataagattt gactatatta ggactattat
     7861 ctgttgagca atcatcaata attaacattt cccattcttg ataagtttgg tttaatactg
     7921 attttatggt tgcttcaata aatttttcag aattatacat gggagtaatt atagatacta
     7981 aattcttctt catattacct tcctcatcat ttataaaata tttatttaat tttacttaat
     8041 acacaatcat atatcctctt gcagttctta ttatcattat atctgaaaaa cttatttctt
     8101 tcattttttt ggttatccat aacctcaaaa ttattttcaa taatatcaat aagtttattc
     8161 acggcttcat cattattata agccaaagac ccaaacattt cactttttaa atctatatat
     8221 gaatcaactt tttccatata ttcatccaaa tcgaattggt aaaacaagat aggtctattc
     8281 atatacaaaa agtctatggc tacacttgaa taatcagtta tatttgcagc tgattttctg
     8341 atttcatttg ctagagttac ccctttatct aaaaacacaa ttcgttttcc tgttatattt
     8401 tcttttatat catctataaa ctcatgcata agatgatgca tataaatttt tacatttata
     8461 tctttctcat ctaatatttt atttaatttg tcatcattta aaaaattcat tatattttta
     8521 aaataatctg tatccgtaaa ttttcctgaa ctaaatttta tccaatctct ccatgtagga
     8581 gtatataata tatctcgagt ttgtgcaact tcatttgttg gtaaattgtc atatcttgca
     8641 ttcccaatta tataaactga gtcatctaac attccccaat catttaccat aacatttctt
     8701 tcaaattcag aacttgctgt aactatatta tagcttttat ataggttatc tataatattt
     8761 ttgaactttt tgttcatagg ttttcttttt ttaaagctta tagtcccatg atttaaaaac
     8821 acttttatcg tttttttatg aaaataatta agaacaggta cagcaaaatt gtatggtgct
     8881 atatctgctg atggtgcatg tgaaaatact atagcttttg aattgtaata atacagatag
     8941 ttttctacac ttcctcttat taattttttg cctggaattt tatcaaatac tttactgtct
     9001 ttatttacta cccaataagt ttctacatca ttatgttctt ttagcatata ctcataaaaa
     9061 aactttgaat tatcattgta tatatcccct gaatgtccac ctataagcca gatatctcta
     9121 ccattaaact tatgcttatt aaatggatat ataaaaaaag ccaaaagcat atttattaaa
     9181 aatttaacct tgtccataaa caccatcctc attataactt gtactgtcta aatccattaa
     9241 ttcttccttt tatagtggca ctatgataat ctctattgga actcaatata agacccccta
     9301 tatttcttac aagttttgat accataactt ttgcaaacgt ataatttttt ctatagacta
     9361 tttccttttt gcaaagcgct ccaaagcctc ttccataatt ataatctttt tgatactttt
     9421 ctttagattt agaatgtttt tttgcaggat ggtaaattat atcatttcca aagtattttc
     9481 ctttaaaacc taaactcaat aagtttaaaa cataatctat ctcttcacca gcaccaaact
     9541 ctccaccaac acccaatttt tcatcaaatc ttgtataatc tttaccttca aaatcaataa
     9601 aaaaagttat ggatgttata gtatccaaaa cgttggaact tgtgatatca caagttccat
     9661 catacatttt cttaaatgca tcaactttat ttgaatccat agttttgcaa ctgtatattt
     9721 tataatcttc atttttatta aagaaattta taactttttc taatgtatca ttttcgtaga
     9781 cacaatcatc atcagggaaa cctataattt gccctacagc attatctatg cctacatttc
     9841 tgttataact caatcctttt ttagagcttt ttatatactt tatatctaac ttatcaatgt
     9901 atttatcaac tatttcttta actttgctat tatcattttg gtctactact ataagttcaa
     9961 agtttttgta agtttgattt tctaagctat ccataagtaa gtatatatca tcatatctat
    10021 ttaatgttgg cattattaat gatattaaca ttactacctc ctacttttca tcttccacaa
    10081 atctatttcc cttttatcat ttaatatcac ttcttttatt agtaatacta ctgcaaaact
    10141 aaatgaagct tctaataata aattttctgc aaaagagtat agtaaaaata taaataaagc
    10201 tactaaatat gcttttttat ctttttctat aaagctttct attcctttat acatcaaata
    10261 cataaataat atacaagcaa ctactcctag tacactaatt atatatacat aagaactatc
    10321 taatggatta gttgctttta tagcaggact atatgaattt ccaaaaggtt ttagaaaatt
    10381 ccccttttca gccaagtata catgccagaa cttaggtcta cttgctaata atctatttaa
    10441 taaagtgctt ttatcaaata ttgtaccaat aattacacta aatagagtaa gtattattgg
    10501 taatgtcttt aggagcattg gcagtccttt tatttttttt atatctatcc atcttattat
    10561 ttctacaaat attaatcctg ctaatatagt gaaaaatcca gttctactat atgtggtttg
    10621 ataaacaaaa aatgcagaac caaataaaat tattctatcc catttattat aatctttata
    10681 tcttaagaat atatatgctg catatatagt aaccatatga taaaatacac tatttggatt
    10741 accaagtcca aaatccattc ttgtaacaag catatctatt ttttctatat atctatagtg
    10801 gacttcctga ttaaatatta atgaaggaaa taaattaaat aataatatag ctaccattaa
    10861 aaaacatgcc gatattatta aataattttt aactataaat ttatcatcta tttgcttagc
    10921 tgatacagct aataaaacga ttaataatat agctccttcc ctatttaata aataaagtaa
    10981 gacacaaact ccaactagta ccatttctgt tatacttttt ctcttatcaa ataaaaaaag
    11041 tagcattagt attcctattg aagaataaaa taacgctgat ttaatcatcc ctatatctat
    11101 atttgggtca ataaatgata tcatatactt tctaagtaat atgataaaca aaacaaatat
    11161 ataaagatat tttctaatca taatatttct atcatcattt aaagtcttca ttttactttc
    11221 tcccttttag cttcgtaaag tattacttgc aaatatttta caacacttcc atatcttatt
    11281 tacacctgtt aagtgtttgc tttctaagaa ataatttctc tttttagccc aactttttcc
    11341 ccaccaatgt atcccaaaag tgttttctgt tatacattct ggtgtaaagt cttctttaaa
    11401 tccaaaagga taaaaatatt ctttgtcgta aacacgtatt ccttcttcat aattatttgg
    11461 gtcaatcttc ttataattct tttccataag atgagtcatt atttttggta ttgtaaacaa
    11521 tgaagaagta agtacttctt tttcataata ctccaataag tcttttaaaa aaggatgtcc
    11581 tttttctaca cctattatag caccatttat atactctcta tcatcttcat acccacagat
    11641 tagcctatta ttttctaaaa gaggagttat atcctttaat atttgcatat ctgtatccat
    11701 ataaactcca ccttgttcat agagtacttt tattcttgta taatcagata tgaatgccca
    11761 aagttttctt ttataacatt cttccaaaaa cttatttcct tttatttctt tctctatatc
    11821 aaagtttttt tcattccact ctactatctc atattctgga agcttttctt tccaagaatt
    11881 tatacatata ttttctatat ttccttttgg accaccaaac catacataat gtattttttt
    11941 aggaatcaaa tgaacacctc ctacatatat tcttgtctat cttcttcttt taactgttct
    12001 actatttttt tgacatcttg agctttatct tttctacaaa ccataactgc atcattcgta
    12061 gatactacta tcaaatcact aatacctatt gttgatatta atttgtcatc tgaatatata
    12121 attgaatttt tagtatctat agtaatattt tcacctcttt tgatgttacc ttcatcatca
    12181 gttggatata ttgcacctag agaatcccaa gaaccaacat cattccatcc aaaatcacca
    12241 ggaactacta taacatcatt acttctttcc ataataccat aatctataga gattgattgt
    12301 atagttgggt atatttcttt tattttttcc atttcttctt ttgttcctaa gtatttactt
    12361 atatattcta atttttcata tacttttggc aagtatctct taaaatcttc taatatttta
    12421 gataccttcc atacgaacat tccactattc catacatact ttttagagtt tacatattct
    12481 ttagcaattt catagtttgg tttttctaca aactccacta cctcatatgc aacatcttct
    12541 atcgtatttt ctctattaaa atttatgtat ccatatcctg ttgatggaaa tgtaggagtt
    12601 atcccaatag ttactagttt atcattattt tctgctatat agatagcttt ttccaaaata
    12661 gatttaaatt ctttttcatc ttttatataa tggtcagctg gatatacaca cataacacca
    12721 tcaccatatt ttttcattat gttaaatgct gcaaagccta tagctgctgc tgtatttctg
    12781 gcacatggct ctggcaatat attactatcc aaacatttat cttttactat atcctttaaa
    12841 gcttccaatt gcttctcatt ggttactata aataaatcat ctttttttgc tagagaatct
    12901 attctgttta tagtttcgtt tattaaagca tcttctccac ttaaatttat aagctgttta
    12961 ggtacttctt gtctactaag tggccagaaa cgagttcctc ctcctccagc cattatgaca
    13021 ttgtatactt tcattattta tctcccctta gctttttata tagaatccac tacatttaat
    13081 atataagata ttaaattgtt caacttaaat tctacatctt cttgattgtc tgaatttgct
    13141 ccaaagtaaa atttaatttt aggttctgta cctgaaggtc ttatagctat ccaagagcca
    13201 tcttcaagta aaaatttaag tacatctgac ttaggtaaat catcaacacc atctttatag
    13261 tctaaaattt tatctacttt tacatcagcc acattatcta ttttaacact tctaaagtaa
    13321 agcatcatct cttttatttt ttttattcca tctatacctt ttaaagttac tgactttaag
    13381 tcctctttgt agtatccaaa tttattatat gtatctatca aagcttcata caagttcata
    13441 ccttttgaag aatagtatgc tgccatttca catatcataa gtgaagatac aacaccatct
    13501 ttatctctag catgagttcc aattaagtaa ccatagcttt cctcatatcc cattataaaa
    13561 cttctatcat tgctttcttc aaacgctttt attttttctc ctataaattt aaatcctgtt
    13621 aaagtattta aacaatctac attataagcc tttgctattt ttgcacctag ttctgatgta
    13681 actatagttt ttattattgt aggattgttt ttaggaagtt tattttcttc aactaaactc
    13741 tctaatatat atctaactaa aagtgaaccg acttgatttc catttaagac tacatattca
    13801 ccacttgaat cttttacaac gatacctact ctatcacaat cagggtctgt tcctattatc
    13861 aaatcagtgt cattattctt tgccatttca atagctatat taaacactga cttttcttca
    13921 ggattaggat actttactgt tgaaaaatta gaatctggta attcttgctc cttaactacc
    13981 attacatttt caaaaccaca ttcatttaag acttttctta ctggtttatt tcctgtacca
    14041 tgaataggtg tatatattat ttttaatttt ttcccgtatt catctattat attttgtctt
    14101 aaaacttgct tcttaacagc ttttataaac tcatcatcta cttcattatc taatatagtt
    14161 attaaatttt tagataaagc ttcttcaaaa tctatacttt taatagtgct gtaatcatca
    14221 atcttattaa cttctgctat tatatcattt gccatatcta tacagatttg accaccatct
    14281 gagtcatata ctttatatcc attgtattct ttaggattat gacttgctgt tattactatt
    14341 cccatagcac actttaaata tctaacagca aaagaaagtt ctggtgtagg ctttaattct
    14401 tcaaaaatat aagcctttac accataagca cttaaagtct ttgctacttc tatacaaaac
    14461 tccctagaca tgtatctact atcatgtgct ataactattc ccttttgttt accttcttct
    14521 ccttgagtct tcatgatata atttaaaacg cccagtgtcg cacgtctaac agtataaata
    14581 ttgattctat tagttcccgc tcctattata cctcttaaac cacctgttcc aaactctaaa
    14641 ttcttataga atctatcttg tatttctttt tcatcatctt ttatgcttaa tagctcattt
    14701 tttgtttgct catcaaaata aggagaattt aaccacatct cataattatt cttataatcc
    14761 atattttcat cctttctgac tctaatttaa aatttcaagg taattatctt cttctaagta
    14821 gtttttgttt tccttttctt aaaaattcaa aagctaagtc catctcttct accttaaata
    14881 aaactatcaa tacagtatat acagaagctc cacctaatac tccagctcca actgatataa
    14941 tttctttaat tgttcctgaa cccataaatg catatagatt attatatatc aataaagtag
    15001 ctactgccat cacaccagat gctaccaaac tttttagacc agtctttata attttatccc
    15061 ctccaaaata tccatttttc tttttaagag atataaataa caatataact gtaattatat
    15121 tggatgtact agttgatata gcaatacctg catgacctaa tggtcttatc aatattaaat
    15181 taagaactat atttattatt aaagctatac ttccatttat cattggcgtt tttgtatctg
    15241 aaagagagta aaatgcccta tataagacat ctcttactcc acaagccaat aaacctagtg
    15301 aatataatct aagcgctata gatgtaagat ctgttgataa cgcatcaaat ttaccccttt
    15361 gaaataatat cctaacaaga ggctctgcta atataatagc tcctatagat ataggaagca
    15421 ccaccaatat aatacaattt gaagatttta caatagtact tataaatcct tctttatcat
    15481 ctttaccaga catttttgct agcttaggat atataactgt tattatagat gtaacaaata
    15541 atgccataac aaactcattt agcctatttg catagttaag agcagacaac tttccatcac
    15601 ccaaagtagt tgccaataat ctgtcaacaa atatatttaa ctgtccaaca gctactccta
    15661 ccaacatagg caatactagg tttactaatt cttttataga ctcatccttt aagtttatat
    15721 atggcttata cttgtaggac ttcttaaatg caaatggcag ttgaaataat agttgactcg
    15781 ccatagccaa tagtgctcct gctggtagta tccatacgtt tttacctgca cttagtgcta
    15841 ttgctgctat tattataata ttatatggga ttcctataag cccaggaatt acaaaactgt
    15901 cattcacctg taaaaacgaa ctaaatatct tacttccact taggaataaa actcctgaaa
    15961 tcattatttt agtaaataat attgctgctt ggaacttagc agggtcgttt ctaaatcctg
    16021 ctgcaaatac tgtaacaaat tgctctgtaa ataaaagccc aataatagct attactatag
    16081 ccattatata gcatatattt aaaacattat tagtaaattt taaggcacct tcatctccga
    16141 gtcttttctt tgtctcaaag tacataggta tataagttgt agcaactgca gagcctatga
    16201 ctgctatgat taaaccaggt atatttaatg ttaatacaaa tacgtctgca tacatacctg
    16261 tcccatagaa atttgcaagt acaagttctc taaggaaacc taatactttt gaaaacatag
    16321 tggctgccat aatccacaat gctgctttag ctgtttttga catcttcttt ctccttatct
    16381 aatttaaact ctaaaagtag aacttttaaa actgcttata aacattattc taattaagta
    16441 aatttaacct atgaaaagct tccttataaa ttaaaaacta tttcgactca tatctaagtg
    16501 ccctaaatgt aatcaatagt aataatagta ttaatactat acaagataag aatgttagat
    16561 taaatatgct cttaaataga ctataatcac ctactgtata cccaacttca actacatcat
    16621 ttatattgct atctttcaag aatttatctt gtgcacgact taagttatca ctacaaatca
    16681 gtattggcat attttctttt gctgatacta ctcccaaaga aatatattcg tttacatcag
    16741 atctgctacc aaagtctaat ttagcagtat agattttctt tatatctttt tcatcataaa
    16801 acttctttat taaatcaaca tttgtacttg acttatttat ttgctttatt ccttctatat
    16861 ttttcaagtt agaatcaatc tctgcaataa attcttttga atcacctaat gcatatattt
    16921 ttttaagatt cttacctttt aagaaatcaa tttgttcctc aaacccttca tctttagccc
    16981 atattattgg cattccactt ttagcggcat aagaatatac agatatggca ttctctaatc
    17041 ctgttgttga gctaagtaaa aatgcttcat caaatcctac tgttctatac atttctctag
    17101 ctatctttaa agatgtatca tatctgtctt ttcctcttat tctttctact tttattccca
    17161 ttttttctat attacgttca gcatctttag atactgcctt taaaccacct actatcgtaa
    17221 ccttctctgg acctagttct tttagataat ttcttgttac tctaccaaga tttttactct
    17281 tagttacaac tattggagca ttttttgcat atgctaaagg tgttgcactt atactatcta
    17341 caattgactc ttcatttaca agaattactt ctttagaatc cttaaatgct cttttattta
    17401 attctgtcga aatctctggt atactccctt ctatcaattc tcttttggga tttgcatctg
    17461 caaatacctc tattgtgcta gaaatagaga ttaacaaaac taacgataat atagtagaaa
    17521 tttttttaat cataagttct cattcctttt cttttttgta ttttttgaca ataaaaaagc
    17581 tctttttaaa gagctttttc attgattagt aatctaatat tttaaaatta tctagctccg
    17641 tctcctgtca atactacttt aacagtttta aagagtatct taaagtcaag taatatactc
    17701 ctatttttta tatagtaaat atcttcttta agtttttctt caggagtgat ttcgtatcca
    17761 ccatttactt gtgcccaacc tgtaagccca ggttttatag cgagcctgtt gataaatcca
    17821 ggtatttcct cattgaattg aacagtaaag ttcggtctct ctggtctagg gcctattaag
    17881 cccatatccc cctttaatat attaaacagc tgtggaatct catcaattct agttttccta
    17941 ataaactttc caaccttagt tattctagga tcatcttttt cagcccattg tgcgccaaat
    18001 ttttctgcgt ctgttctcat agatcttaat ttatatatat agaatcttct cccgcatttt
    18061 cctagtcttt cttgcttata agttattggt cctttgtcct ctattttaat aagaattcca
    18121 aatattgcta ttaaaggtaa acctatcaca agtcctatta tagataaaac taaatccata
    18181 attctttggt acaagtcgaa taaaaccgtt ccttttacta tgctatagtc aatctcactt
    18241 gcaatttctt tatctgcccc tggatagctt ttaattttag gtatttcaca ctcatcatta
    18301 gtatatccag acatagttac ctccatattg gaataaaaat ttttttaatt cttaatttca
    18361 acttatttct atcttatttt tgacttattt ctatattata ctcaataatg agcagattat
    18421 caatacaaga aacatcattg taaacaattt gattctttac aaaaatatat catctcttgt
    18481 tatattttac attataacag gagatgatat gttttgcttt aatatttttt attttatttt
    18541 actgtatctt ctattcctat tccaatttga gttcccattg tttttacttt ttctgcagta
    18601 tttaacttat ccatatcgct cttattgtca ataaatgcac attcaacaag tattgctgga
    18661 taattgttat ttcttaacac atataggtaa tcttttccat tatcaagtgt tcttgtcttg
    18721 attcctctat ttttcatgtt aaatttttct agtattcttt ttaagatatt tgatgctgca
    18781 gtcttagttg ttccaccatt tttatctttt actttgtaat aaatttccac accattacca
    18841 gctccattag acgcattgta atgtatactt gtaaataaat ctggctttat agtgtttgat
    18901 aatgctgttc tttctcctaa agccattgtt ttgtctgtat ctctagtcat aacaacattt
    18961 ataccttttg aacgtaaata ttcagtagtt gctaatgctg tattaagagt atatttcttt
    19021 tcttgtgctc caccatttaa tccacttgtt gcccctgaat cagaaccccc atgacctggg
    19081 tctatcacta cagtttttcc tgctgctgaa cccgaattat ctggttctgt tggtgcattg
    19141 tgttttgata aactagatgc tatagaattt ataacactat ctttcatccc atcaccaatt
    19201 tgatatactg ttcctgctgt tttttctgat aagtttgtgc tatggtatgc agaaacataa
    19261 gtctttggag ttataagtat tggagctttt aatttagctg ctaaaggtcc tgctgttatt
    19321 gagtcaacta ttatgtcaga ttttgcaact aacattgcac tcaactcttt atctggatag
    19381 aaagtcttaa ttacatttgc atttgtttca tgtctatctg ctccagaaac tctatttttt
    19441 gaagtaccat tttttgctat tttagatatt tggtctataa tttttgatga taaactttga
    19501 ctaccaccta tgtaataagc ttcttctaaa ccttgtgaag ataaccaatt atatgtacct
    19561 tgtggtacag agtctttatt agctaatatt ataggttgtt ggtcttcacc agcttttgat
    19621 gaaatattaa gagcatcata ttcaccagca tatccatttg ctatgtatat tttattaaca
    19681 tcatgatact tatctatttc ttttgctata agtaaagatg tttcatgtct atcaactcca
    19741 ccaatacgag ttacatttac atttacagca gatttaattt gagatactgc cttttgtgaa
    19801 actgaaccat catcacctat aattattaca tcacttggat ttagacgttt taattctgct
    19861 tttgtacttt ctggtatatc atctttattt gcaagtaata ttggtgcatc atatgtagat
    19921 gcaagtggag tagctgtaat tccatctgct gctaattctc cattaactat tacaacctta
    19981 ctagacccat ctttccaacc ttgtttactt atctcaacag cagtttcaaa tctagtagct
    20041 ccagcaagtt tttttactgg cgcagaagtt tttctcatat attcatttac tgcttttgtt
    20101 gaatttgcat cacttattat aaactcttgt gtaacatcat aatccttaag atttaatccc
    20161 atagactcta agtcttcttt gtttaaaact ttctgttcat ctttaccatt tatttttatg
    20221 ctttgaagtt cccatacatt taagtattct gggtctttgt tatagtttat tacaccttca
    20281 tatgaatctg tcttttcatt gtaatttaaa gtagcttcaa gtggcatatc ataacacata
    20341 aaatttaatg ttattgaatc agcatttaat ttttctttaa attttacact tgcattagat
    20401 ttacttccta acactacact ttttctttgt aaatttatat taatatctga attagattct
    20461 gtatttgcag tagtattttc agccgctaaa gctacgtttg gtgccaccat tgctacagac
    20521 aacattcctg ttgccaataa ttttgttgtt tttttcatca tatcccccct aattttttgg
    20581 ttctttaaat ctttaaatct tttttaatac atcttaagct tgttttatat tacataaatt
    20641 caatattatg taaatctttt ttcattatag cacaaaaaat tacaaattgt aaactttttg
    20701 taatctttta tggcatggtt tttaaatttt atcgaggaga aattttgatt atatttgata
    20761 gtttccgtat atttgaacaa atcaaagact ttatcatcta aaaatattgc actaaatttt
    20821 aataaatatt tttttcttgt acattataga cattactata acccagaata ggacatacaa
    20881 taaagaaaat ataagagaat cccaagttgt acctgcccaa ggtgttataa gttcatatgt
    20941 agtccactct accaaggtag ttggataatc gactttgttc gtaagttttg gaacattcca
    21001 aaaaacatga ctcaatatct caaggcacat atatgtaaaa atagggctac ttccaagtgc
    21061 tattattggg gtaaatattt tacttttatt tttgatgtca catataaaat aaaatattga
    21121 cagtaacata ccataactgc cagccattaa aagtacaaat gagctagacc ataatctttt
    21181 attaaatgga aaatactgat taaagataaa agcacctatt agcaggatta tgctcataac
    21241 cagtatttta aagaattttt tatattctcc tatgttttct tttaaaagta cacatcccat
    21301 agtgcatccc aacatacctg aagaaattgc tactatacta gttaaaaaac catctggttc
    21361 aaattctggc ttgtacaaat gtcccttgaa gaaatgtaaa tccactaact gtgcaagaga
    21421 accttctagc tcaaatccat aaggttttgc taatatgtag tacccaacta ttataaatgt
    21481 agctatacat agaaaagtaa ttattgtagc agtacttcca acatttaatt tttttagtag
    21541 taaatatact aaactagtca caaaatagac taatcccata cgttgaagta ctccaagtat
    21601 tctcacagaa tttaaatcag gatttcctag gtaatttaag aaaaatccaa ataatatcaa
    21661 taagatactt ctcttgaata tactaagtat tatactcagt gtggatttat tattttttag
    21721 tttactattt attgatattg gaattgtaac acctaaagat ataacaaaaa aaggaaatgc
    21781 aaaatccgca agtgttacac catgccatac agcatgtctt aattgaggat acattctcat
    21841 ccaagtccca ggattattgc agactatcat gagggctatt gatagccctc ttattatatc
    21901 tattgattta atcctactat tcgtaagttt agaatctaca acattatttg aaatt
//
LOCUS       DAMJWO010000073        21595 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.074, whole genome shotgun sequence.
ACCESSION   DAMJWO010000073 DAMJWO010000000
VERSION     DAMJWO010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21595
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.074"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            110..1561
                     /locus_tag="PC366_002793"
     CDS             110..1561
                     /locus_tag="PC366_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HDF2578290.1"
                     /translation="MNFLNGILTSINNAVVFVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLEKVSEWHRELSEEHLG"
     gene            complement(1781..2242)
                     /locus_tag="PC366_002794"
     CDS             complement(1781..2242)
                     /locus_tag="PC366_002794"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HDF2578291.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVSP
                     ENIEIVWVPGAFEIPLVAQKMAKSGRYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDSELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLN"
     gene            complement(2348..3541)
                     /locus_tag="PC366_002795"
     CDS             complement(2348..3541)
                     /locus_tag="PC366_002795"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HDF2578292.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDESRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDTYSNEEHIALTYGNINIENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRIPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            complement(3564..4229)
                     /locus_tag="PC366_002796"
     CDS             complement(3564..4229)
                     /locus_tag="PC366_002796"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HDF2578293.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTILLTKNVGDFVNLESDVIGKYVNNFMANNYKELNSNSSNHKSNIDKDFLFK
                     NGF"
     gene            complement(4263..5366)
                     /gene="ribD"
                     /locus_tag="PC366_002797"
     CDS             complement(4263..5366)
                     /gene="ribD"
                     /locus_tag="PC366_002797"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HDF2578294.1"
                     /translation="MNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKDSNIIGK
                     GYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKRVVI
                     STLDPNPLVCGNGVKKLKDNNIDVTVGILEDEARDLNEAFFYHIKNKRPLCIVKSAVS
                     LDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQEKVS
                     HPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESIKLSMLKENNVETIISPSKNNL
                     VDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNKLVDKVKLFLSPKIIGGKDAPTFVS
                     GEGINHLSDSTQLTINNVTLIDGDILIESDVLN"
     regulatory      complement(5498..5619)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            5808..8291
                     /gene="recQ"
                     /locus_tag="PC366_002798"
     CDS             5808..8291
                     /gene="recQ"
                     /locus_tag="PC366_002798"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HDF2578295.1"
                     /translation="MNKKLLEILSKYYGYTSFRKGQESIINSILSEKDVLAIMPTGGG
                     KSICYQIPALILDGMTIVISPLISLMKDQVDALKTMGISAAFINSSLSSKEFNEILNN
                     IRKNNYKILYIAPERLDAQEFIELINNNNVSQVAIDEAHCVSQWGHDFRLSYRRISDF
                     IKNLPKRPIVTAFTATASEEVRTDIINLLCLENPDYYITGFDRENLSINIVKSSSKNK
                     YILDYIQNHKNESGIIYVATRKEVENIYNGLSKRNISVSKYHAGLSKNERSKNQEDFI
                     NDNVDIMVATNAFGMGIDKPNIRWVIHYNMPQSIENYYQEIGRAGRDGEKSECVLLFS
                     PGDVHIQKYLIDIGVENPERKLFQHKKLQYMIDLVYSNSCYRKTILSYFGENYIDNCN
                     NCSNCLVEGEIVDKTIDAQKVISCVARMKRSYGVTTIVDVLRGSKNKKILQLGLNTLS
                     TYNIMRDYSSEDLKNFVNTLVSHGFLDLVETLGNGNRGSFPTIRLNEMSMKVLKGEVK
                     VEFKEIVMTKSLEVEDELYNALRELRHSIASEERIAPYMVFGDGTLRAMSSSYPINKE
                     EMLDISGVGEIKYQKYGRDFEAVIKEYVEKNNINKKIDEKNVDLKNVNSDFLEVNTDK
                     VLYEKLLVIREEYATKEKLPAYMILANKALKEISGRYPLDEEQLKDISGIGGVKFEKY
                     GANILAEVNKYVKENNINVIWEKKGKRKLILDGESRKNNEIALDLLNQGKDIQSISQE
                     IEVSLSTIIGYVHDYVKDGHSISFELGLENFYNEDKKKMILEVCEKVGYDNLNNIKRK
                     LPDSIKYENIRAVMLDSYLENLKNNIIAE"
     regulatory      8379..8490
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            8632..9933
                     /gene="thiC"
                     /locus_tag="PC366_002799"
     CDS             8632..9933
                     /gene="thiC"
                     /locus_tag="PC366_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HDF2578296.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            9987..10181
                     /gene="thiS"
                     /locus_tag="PC366_002800"
     CDS             9987..10181
                     /gene="thiS"
                     /locus_tag="PC366_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HDF2578297.1"
                     /translation="MKVNGKEIEFEKDLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            10174..10977
                     /gene="thiF"
                     /locus_tag="PC366_002801"
     CDS             10174..10977
                     /gene="thiF"
                     /locus_tag="PC366_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HDF2578298.1"
                     /translation="MVKIKIFVNELLTDVEENTTAYKVRDSYNNKCDVLVLNGYPIKT
                     DMPLCENDKLTLIQKGVKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DIFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            11040..11810
                     /locus_tag="PC366_002802"
     CDS             11040..11810
                     /locus_tag="PC366_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HDF2578299.1"
                     /translation="MDKLVLGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMA
                     RAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLGNL"
     gene            11827..12930
                     /gene="thiH"
                     /locus_tag="PC366_002803"
     CDS             11827..12930
                     /gene="thiH"
                     /locus_tag="PC366_002803"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HDF2578300.1"
                     /translation="MSFYDVIEKYRDFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEDMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEAISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYEFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPHIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            12931..13620
                     /locus_tag="PC366_002804"
     CDS             12931..13620
                     /locus_tag="PC366_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HDF2578301.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELRK
                     LYMKIKTKINCIDFQEQISDESLKTNINQKECRNKFKVNFIINSNIEFFEKVDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVEEVDYLEKLIRNQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAIMSTIMRSKDIK
                     KTISNYNEKLN"
     gene            13808..15202
                     /gene="yfcC"
                     /locus_tag="PC366_002805"
     CDS             13808..15202
                     /gene="yfcC"
                     /locus_tag="PC366_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HDF2578302.1"
                     /translation="MTDSKKKRFIIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLVGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
     gene            15719..17086
                     /locus_tag="PC366_002806"
     CDS             15719..17086
                     /locus_tag="PC366_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HDF2578303.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILNYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIINCICREYECYGEYLEEKEKLMNTFKEKI
                     IQIFE"
     gene            17111..17719
                     /locus_tag="PC366_002807"
     CDS             17111..17719
                     /locus_tag="PC366_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HDF2578304.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGKNSRMGRDKAFLE
                     LHDKLFIEIAIEAFKNFDELIIISNNEELYSKYDIKVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNNQIVERIANKMNDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYEKLTKV"
     gene            17767..18138
                     /locus_tag="PC366_002808"
     CDS             17767..18138
                     /locus_tag="PC366_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HDF2578305.1"
                     /translation="MNLLKCDSWAVILNNSDKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLSLYDELTR"
     gene            18317..18655
                     /locus_tag="PC366_002809"
     CDS             18317..18655
                     /locus_tag="PC366_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HDF2578306.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAEAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            19122..19625
                     /locus_tag="PC366_002810"
     CDS             19122..19625
                     /locus_tag="PC366_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HDF2578307.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLI
                     KDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
                     CATKKSE"
     gene            19672..20631
                     /gene="moaA"
                     /locus_tag="PC366_002811"
     CDS             19672..20631
                     /gene="moaA"
                     /locus_tag="PC366_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HDF2578308.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKIRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRIFELEKCGLNKVNISLDSLKEYKYKSVTRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLIENKCSDTNRRMYEIGG"
     gene            20635..21105
                     /gene="moaC"
                     /locus_tag="PC366_002812"
     CDS             20635..21105
                     /gene="moaC"
                     /locus_tag="PC366_002812"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HDF2578309.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDVDDYMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            21141..21572
                     /locus_tag="PC366_002813"
     CDS             21141..21572
                     /locus_tag="PC366_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HDF2578310.1"
                     /translation="MAKVVSINISEKKGVIKVPVPCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENVTTEGIEVFSLPVGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVKVLKEGIINVNDSIDVI"
BASE COUNT         8313 a         2336 c         3743 g         7203 t
ORIGIN      
        1 tttataaata ttataattaa attaatgaat ttttaacaag gaattattca tttttttgat
       61 tttaagattt attgagaaaa caaaactaaa taggggggta attaatataa tgaatttttt
      121 aaatggtatt ttaacgagta ttaacaatgc agtagtattt gtaaacaatt acttatggtc
      181 gtatatctta attataatgt tagttgtaat tggtatttac tttactatta aaacaaattt
      241 tgtacaattc agatatttta tagaaatgtt tagacttctg ggtgatggta cagcgaataa
      301 aaatgcaaaa aaggaaggaa aaatctcttc atttcaagca ttttgtataa gtacatcttc
      361 aagagttgga actggaaata tagctggaat agcaattgca gtggtagcag ggggacctgg
      421 tgctgtattt tggatgtggc ttatagcatt aattggttct gcatcaagct ttgttgagag
      481 tacattagct cagatttaca aagtgaaaga tggtcaagct tttagaggtg gaccagcgta
      541 ttatatggaa caaggtctaa ataaaaaatg gatgggtatt ttattctcaa tacttataac
      601 tatatgttat ggttttgtat ttaatgcagt tcaagcaaat actgtttcac ttgcatttaa
      661 taatgcattt ggaataagta aaatggctat gggaataggt cttggaattt taactgcaat
      721 agttattttt ggtggagtgc atagagttgc aaaagtttct gaaataatag ttcctgtatt
      781 tgcaggatta tatatattag ttgctttggc tatagttgta atgaatataa cagagatacc
      841 aagtgttata gcattgatag ttgaaagtgc atttgatttt aaaggaatgg cgattggtac
      901 atttatggga gttgtaatga ctggagtgaa gagaggtcta ttttctaatg aagcaggtat
      961 gggtagtgct cctaatgctg ctgcaacagc acatgtaact catcctgtaa aacaaggttt
     1021 aattcaatct ttaggtgttt ttacagatac tataataata tgtagttgta cagcattcat
     1081 ggtattatta tattcaggtt atagtagtag tggagcaact ggaattgaat tagctcaaga
     1141 agctttaact catcatatag gaccagttgg aaatatattt atagcagttt gtatattctt
     1201 gtttgcattt agttctatag ttggtaatta ctattatggt gaatcaaata tggagtttat
     1261 gagtggaagt aagactaaac ttaatgtatt tagagttttt gttgtaggca tggttttatt
     1321 tggttcactt actcaagtag atgtagtttg gaatcttgca gacttattta tggcattgat
     1381 ggcgataata aacttaatag caatagcact tttaggaaaa tatgcattta ttgctttaaa
     1441 agattataca agtcaaaaaa aatcaggaat aaaagaccct gtgtttattg cagatgaaat
     1501 agaaggccta gaaaaggtat cagagtggca tagggaatta tctgaggaac atttaggata
     1561 aaaaatagta taaaattata aaaccatttt gaaagactag agtatgtata tgctttatat
     1621 gaatataata ttgaattaat ttatattact ggaattttta attccagtaa tattttttta
     1681 ttatataatt tagctttatt aaaagttttt attattaaaa atagcttatt tatcgtaaag
     1741 tgaatgatat tggtttttta attattatga atgttggtat ttaatttaaa gacttaaata
     1801 aatttgccat ttctagcgca ttcatagcac aatcataacc tttatttcca gcttttgtac
     1861 ctgctctttc aatagcttgt tcaatatttt ctgtagttac gattccaaat ataacaggta
     1921 attcactgtc taaagatact tttgctatcc ctttagagac ttcactacat acataatcat
     1981 aatgagaagt agcccctctt ataacacagc ctaaacagat tatagcatca tacctaccac
     2041 ttttagccat tttttgagca acaagaggaa tctcaaaagc tccaggtacc caaactattt
     2101 ctatattttc tggagaaacg tcatgtctta aaagacagtc ttcagctcct gataaaagtt
     2161 ttgatgttat aaattcatta aaacgagaat ttattatacc tatttttaaa tcttttccaa
     2221 taagttttcc ttcatatatc atttttattt cctccaattt tatttatgtt atagatttat
     2281 atttataaat atctttaatt ttaattataa aaaactactt agtagaaaaa tatcatcata
     2341 taatcattta tataatatct aaaagatgtc ccattttatc ttttttagtt tttaaatata
     2401 gcttattaaa gtcattaatt tcttcattaa tagggattct attttcgatt tttattccat
     2461 atttctctaa ttgatttatt ttatccgggt tattacttaa aagatttata ctttttatgt
     2521 ttaaattttt taatatttga gcagccatat agaaatctct catatcttct tcaaatccaa
     2581 gcattaaatt tgcttcaaca gtatcgtaac cttcttcttg aagtttataa gccttaattt
     2641 tatttaaaag gccaatacct ctaccttctt gcttcatata aattaaaact ccacttccat
     2701 tttccacaat tttcttcata gaagattcta gctgtaatcc acaatcacat tttagagagt
     2761 ggaacacatc tcctgttaaa cattcagaat gaagtctaac tagagtattt tctatattta
     2821 tatttccata agtaagggca atgtgttctt catttgaata agtatctcta tatcctatga
     2881 tttcaaaatt tccatatttt gttggaagga aagcactaga tactttttct atagtagttt
     2941 catttatttt gcggtattct ataaggtctt ttatagtgat gatttttaaa ttatgctttt
     3001 ctttgaaaat cattaaatca tcaactcttg ccattgtacc atcatctttc attatttcac
     3061 agataagacc aatctcttta aaacctgcaa gtctagcaag gtctactgag gcttctgtat
     3121 gtccatccct gacaagaact ccaccagttt ttgctattaa aggaaatatg tgaccaggcg
     3181 ttttgaaatc tttacttgta gaattttcat cacagaacaa ttttacagtt tcagctcttt
     3241 catatgcaga tataccagtt agagtatctg ctccatctat agtaacagta aaggctgttt
     3301 gaaatgtatc tgtattttct ctaaccataa gaggtatatt aagactttta aatttttttt
     3361 cagtggcagg tagacaaatt agacctctac catatgtagc cataaaattt attgattcag
     3421 gagtagccat ttcagctgcc atcaataaat ctccttcatt ctctctactt tcatcatcaa
     3481 ctacgattac cattttccca ttttttatat cttcaatagc ttcttcaata gtattaaaca
     3541 tgtaattcac tcctttatta tttttaaaaa ccatttttaa ataaaaaatc tttatctata
     3601 tttgatttat ggttactact attagaattt aattccttgt agttattagc cataaaatta
     3661 ttaacatact ttccaattac atcgctttct aaattaacaa aatctccaac attctttgtc
     3721 aagagaatag tgttaatttt agtatgaggt ataatagaaa ccttaaatat ttcatcatct
     3781 aaatatgata tagttaaact tacaccatca atagcaacag aacctttgag tatcattgaa
     3841 gataaaagtt ttttatcagg tcgtatactt actaaaactg cattttcatc tttttcaaat
     3901 ttgcagatag ttcctttacc atcaacatga cctgttacta tatgaccacc aaatcttgaa
     3961 gaaagactca tagctctttc aagatttacc ttatcatttg catttaataa acctaaattt
     4021 gtggaacgaa ttgtctccat cataacatcg gctgtaaatt cattttttcc gaggtttgaa
     4081 acagttagac aaactccatt tacggctata ctatctccaa gatttgtgcc atctaatatt
     4141 ttatttgata gtatggttac ttttccactc ttaccattag cagtaatttt tctaagtatt
     4201 ccaacttctt ctactatgcc agtaaacatc ctaacctcct atatgaatgt attaacaaaa
     4261 atttaattta aaacatctga ttctataaga atatcgccat ctatcaaagt tacattattg
     4321 attgttaact gtgttgaatc tgacaaatga tttattcctt ctccagaaac gaatgtaggt
     4381 gcatctttac cacctataat cttgggtgat agaaataatt tgactttatc aactaactta
     4441 tttctaaaga gactgtcatt gagagtagca ccaccttcaa ctagaacaga atcaatgttt
     4501 aactctccta atttatacat tacaaattcc aaatctacta agttgttttt tgaaggagaa
     4561 attattgttt caacattatt ttcttttaac atagataatt ttatactttc tttgcaacat
     4621 gtgaaaacta tagttttact ggttttatct ttaaccaaat tactattaag tggcaacttt
     4681 aggtgtgtat ctattactat tcttgtagga tgagacactt tttcttgatt gagcctgcaa
     4741 gttagtaaag gattatcgtt caaaactgta tttatgccaa ccattatact ttggtattta
     4801 tttctgtatt tatgagttag ataccttgat gattcattag atatccattt tgattctagt
     4861 gattttgtag caattttacc atctagactt actgctgatt ttacaataca aagaggtctt
     4921 ttgtttttta tatgataaaa aaatgcctca tttaaatctc ttgcttcatc ttctaatatt
     4981 cccacagtaa catcaatatt gttatctttt aattttttta ctccattacc acaaacaagt
     5041 ggatttgggt ctaatgtaga tattacaact ctcttaatct tattttgtat aattttatct
     5101 acacaaggag gcgttttccc ataatgagaa catggttcta agtttacata aagagtagag
     5161 tcttttagac tttgtttagc actgtttata gcatttactt cagcatgatt agagccaaat
     5221 ttctcatgat atcctttgcc tattatatta ctatctttaa caattacaca cccaactaat
     5281 ggatttggat ttacaaagcc ttctccattt ttagccaatt caatagcttt tttcatataa
     5341 taaatatctt tttctttttg attcacaata tgtacacctc ctgtttaatt ggataatttt
     5401 taaacaaaaa accctgagaa ttaactcagg gtttagaata atctacaata aatgtttaat
     5461 aaaagtagaa gaaaattgct ctacaaaaac actcattaaa tatcttcttc catccagact
     5521 ttactgtcgg ctttggaatt taaccaaatc aaccaagttt taccttggct cgcgggctat
     5581 accgccgatt gggaatttca ccctaccccg aagattaagt attaaattta tatttagaat
     5641 gtatcataaa ttattttact ttgcaaacta tttttttaaa aaatatatgt taatatataa
     5701 tatagaatgt ctataaactt tgaaatacca cgattgtgaa tataaaaata aaaatttgaa
     5761 cataatcagg aaagaagtct aattaattta aattaggaga gtaatatatg aataaaaaac
     5821 ttttagaaat actatcaaaa tactatggat atacaagttt tagaaaaggt caggaatcta
     5881 taataaattc tatcttaagc gaaaaagatg tgttagctat tatgccaaca ggagggggga
     5941 aatcaatatg ttatcaaatt ccagctttga ttttagatgg aatgacaata gtaatttctc
     6001 cacttatatc acttatgaaa gaccaagtag atgccttaaa gactatggga attagtgctg
     6061 cttttataaa tagttcatta agcagcaaag aatttaatga aatattaaat aatattagaa
     6121 aaaataatta taaaatactc tatattgctc cagagagatt agatgcacaa gagtttattg
     6181 agctaataaa taataacaat gtaagtcaag ttgcgataga tgaagcacat tgtgtatctc
     6241 aatgggggca tgattttagg ttgagttata gaaggatttc tgattttata aaaaatttgc
     6301 ctaaaagacc tatagttaca gcatttactg caacagcttc agaagaggta agaactgata
     6361 taataaattt actgtgttta gaaaatccag attattatat aactggattt gatagagaga
     6421 atttatcaat aaatatagta aaatcatcta gtaaaaataa gtatatttta gattatattc
     6481 aaaatcataa aaatgagtct ggaattatat atgttgcaac tagaaaggaa gttgaaaata
     6541 tatataatgg tttatctaag agaaatatat ctgtatcaaa atatcatgca ggtttatcta
     6601 aaaatgaaag aagtaaaaat caagaagatt ttataaatga taatgtggat ataatggtag
     6661 caacaaatgc atttggaatg ggtattgata aacctaatat aagatgggtt atacattaca
     6721 atatgcctca aagtatagaa aactactatc aagaaatagg tagagctggt agggatggag
     6781 aaaaaagtga gtgtgtactt ttattttctc caggagatgt acatatacaa aaatatttaa
     6841 ttgatattgg agttgaaaat cctgaaagaa aattatttca gcataagaag cttcaataca
     6901 tgattgactt agtttacagt aattcatgct atagaaagac aatattgagt tattttggag
     6961 aaaattatat agacaattgc aataattgta gcaattgttt agtagagggt gaaatagtag
     7021 ataaaactat agatgcacaa aaagtcattt catgtgtagc tagaatgaaa agaagttatg
     7081 gtgttactac tattgtagat gtacttagag gttctaagaa taaaaagatt ttacagcttg
     7141 gattaaatac tttgtctaca tataacatta tgagagatta ttctagtgaa gacttaaaga
     7201 attttgtaaa tacattggtt tctcatggtt ttttagattt agttgagact ctaggcaatg
     7261 gaaatagagg tagttttcct actataagat taaatgagat gtctatgaaa gttttaaaag
     7321 gtgaagtgaa agtagagttt aaagaaattg ttatgacaaa atcattggaa gtagaggatg
     7381 agttatataa tgctttaaga gaacttagac attcaattgc aagtgaagaa aggatagctc
     7441 catatatggt atttggagat ggtacactta gagccatgtc tagtagttat ccaattaata
     7501 aagaagaaat gctagatatc tctggagtag gagaaattaa atatcaaaaa tatggtagag
     7561 attttgaagc agtaattaaa gaatatgtcg aaaaaaataa tataaataaa aaaatagatg
     7621 aaaaaaatgt cgatttaaag aacgttaata gtgatttctt agaggttaat acagataaag
     7681 ttttatatga aaaactgtta gtcattagag aagaatatgc aacaaaggaa aaattacctg
     7741 catatatgat tttagccaat aaggctttga aagaaataag tggaagatat ccacttgatg
     7801 aagaacaatt aaaagatatt tctggcatag gtggagtaaa atttgaaaaa tatggagcta
     7861 atattttggc agaggttaat aaatatgtaa aagaaaataa tattaatgtt atttgggaga
     7921 aaaagggcaa aaggaagtta atattagatg gagaaagtag aaaaaataat gaaatagcat
     7981 tagatttgct aaatcaagga aaagatatac aaagtatcag tcaagaaata gaagtttcat
     8041 tgtcaaccat tattggatat gtgcatgact atgtaaagga tggacatagt atatcatttg
     8101 aattaggact agaaaatttt tataatgaag ataaaaagaa gatgatttta gaagtttgcg
     8161 aaaaagttgg ctatgataat ttaaataaca taaaaagaaa acttccagat tcaataaagt
     8221 atgaaaatat aagagctgtg atgcttgact cttatcttga aaacttaaaa aataatatta
     8281 tagcagagta atttttaact taataaaaat aaaatttgta ttattgtgtt gaactaataa
     8341 ttttgctgtg ttatactgaa tttgtaaaaa taatgaaaaa ttagagctag gggcgctaga
     8401 attggctagc tgagagataa agccgtaact tacaaaccct aataacctga tcaagataat
     8461 gcttgcgaag ggaagctttt taatataatt ttattatata aataggcaaa ttattcaatg
     8521 ttaggagaaa tttgtctaag tgtatatacg attataagag tgctttccaa acgaggaaaa
     8581 gcactttttt tattttcaaa aactataact ttaatcttgg aggattgtaa tatgaactat
     8641 acaacacaaa tggatgctgc tagaaaaggc ataataacta aagaaatgga aatcgtttct
     8701 caaaaagaac aggtagatgt aaatgaatta agagaattaa tagcaaatgg acaagttgtt
     8761 ataccagcta ataaaaatca taaatcttta agtgcagaag gtgtaggtaa aaatttaaga
     8821 acaaaaataa atgtaaatct aggaatttca agagattgta aggatataga aaaagaactt
     8881 gaaaaagtta gagtagcaat agacatgaaa gctgaagcta taatggattt aagtaattat
     8941 ggcaaaacta gagaatttag agaaaaggtt gttgaaatgt cacctgcaat gataggttca
     9001 gtacctatgt atgatgcagt aggatatttg gaaaaagaat taaaagatat aacagaagaa
     9061 gagtttttaa atgtaataag acaacatgct attgatggag tagactttat tactatacat
     9121 gcaggtctta caagaagtgt ttgccaaaaa ataaaaaatc atgagagatt gactcatata
     9181 gtatctcgtg gaggttcttt attgtttgca tggatggaat taaataataa ggaaaatcct
     9241 atttatacta attttgataa aatattggat atatgtgaag aatatgatgt tacattgagt
     9301 ttaggagatg cttgtagacc aggttgtata aaagattcta ctgatggtgt tcaaattcaa
     9361 gaacttgtag tattaggtga acttactaaa agagcatggg aaagaaatgt acaagtaatg
     9421 atagaaggtc ctggacacat ggctattgat gaaatagaag caaatgtagt attagaaaag
     9481 agattatgcc atggagcacc tttttatgtt cttggaccat tggttacaga tatagcacca
     9541 ggttatgacc atataacaag tgcaatagga ggagctttag catgtgctaa aggagtagat
     9601 tttttatgtt atgtaactcc agcagaacat ttaagattgc ctaatttaga tgatatgaaa
     9661 gagggtataa tagctgcaaa gatagctgct catgcaggag atatagctaa aaatgttaaa
     9721 ggtgctcgtg aatgggataa taagatgagt aaagctagag ctgatttaga ctggtgtgag
     9781 atgtttagac ttgcaataga ccctgaaaaa gctaagagat acagagatga atcaactcct
     9841 actcatgagg atagttgtac tatgtgtgga aaaatgtgct caatgagaac agttaagaaa
     9901 atattaaaca atgaggaact taatctaata taatttttgg ctagtatgac tggaataaaa
     9961 agaagctgaa aagaggaggt gatttagtga aggttaatgg gaaggaaatt gaatttgaaa
    10021 aagatttgac tgttatagat ttattaaata aatataattt aaaaagtgat agagttgtag
    10081 ttgaagtgaa tttagagata attgaagaat ctaactacaa tacatatgta ttaaaagacg
    10141 aggacattgt agagcttatt agctttattg gaggtggtta aaataaaaat atttgtaaat
    10201 gaattattaa cagatgttga ggaaaataca actgcttata aagttagaga tagctataac
    10261 aataaatgtg atgtattggt gttaaatgga tatccaatta aaacagatat gcccctttgt
    10321 gaaaatgata aattaacact tatacaaaaa ggagttaagc catcacttga tgaattggaa
    10381 agcttgttga ttgctagaca tactccaaat atacataata aattaaaaaa agggaaagtt
    10441 gctatattgg gattgggggg acttggttcc aatatagcta tctctttagc tagaatagga
    10501 gtgggagaac ttttacttat agattatgat gttgtagaac catctaattt aaatagacaa
    10561 cagtatttta tagatgatat aggaaaacta aaaactgatg ccatgataga aaatataaaa
    10621 aaaataaatc catttataaa attaaataaa cgagatattt ttttaaacaa gaacaatatg
    10681 gatactatta aggattcaga tttaataatt gaggcctttg atgatgcttc atgtaaagca
    10741 caggtatgta attatgtatt aataaattta aaagataaat atttaatagc atcatctggt
    10801 atggcaggtt actatgattc aaatataata actactaaga agataaaaga caggttttat
    10861 atatgtgggg attttgtgaa tgaagctaaa tttggtgaag ggcttatggc tccaagggtt
    10921 gccatctgcg caaatcatat ggcaaatttg gcaacgcaaa tacttataga tatgtaaata
    10981 ttaaaattag atataaaaaa gattgaatat taaaaaaatt taacgtggag ggaaataata
    11041 tggataaatt ggtacttggt ggacatgaat ttaatagcag attattggtt ggaacaggta
    11101 aatatggttc aaataatata ttgcctgagg taataaaaga aagtggaagt gaaataataa
    11161 caatggcact tagaagagtg gatttagaca ataaacaaga aaacatatta acgtatattc
    11221 caaaagagat gacaatactt ccaaatacat caggagctac taatgcagaa gaagctgtaa
    11281 gaatagctag aatatctaga aaaatgggat gtggagattt tataaaaata gaagtaatat
    11341 cagatactag atatttactt cctgataatg aagaaactat aaaagctaca aagatacttg
    11401 ctgatgaggg gtttatagtt cttccatata tgacaccaga cctttatgct ggaagaagac
    11461 ttatagaagc taatgcagcc gcagttatgc cacttggagc tccaattggt tcaaatagag
    11521 gtcttcaaat gaaagaaatg ataagaataa tgatagatga gttggatata ccaataatag
    11581 tagatgcagg tattggaaaa ccatctcaag ctatggaggc tatggaaatg ggagctgatg
    11641 cagtacttgt caacactgct atagcttcag caggagaccc tgtacaaatg gctagagcat
    11701 ttaaattagc tgtagaaggt ggaagagaag catatattgc aaaaacagga aatgtgtcag
    11761 aatttgcaaa tgcatcttct cctttaacag gttttttagg caatttatag aaagtggtga
    11821 ttggtgatga gtttttatga tgtaatagaa aaatataggg attttgattt tgatggatat
    11881 ttaaataatg ttactgataa tgatgtttta agaagtttat caaaagacaa gcttgaagat
    11941 tttgatatat taaatttgct ttctaaaact gcagtaaaac atttagaaga tatggcacaa
    12001 aaagcacata aattaagtgt tcaatacttt ggtaaaacag tatgtttata tacaccaatg
    12061 tatatagcaa attattgtgt taatcaatgt gtttattgta gctataatat aaagagtgga
    12121 ataaaaagaa aaaaattaac tatggatgaa attagagaag agggagaagc aatttcaaaa
    12181 gaaggtttca aacatctact tgttttgact ggagaaagta gttttcactc aagtgtagaa
    12241 tatataggtg aggctataga aatattaaga gagaaatttc cctctatagg tatagaagtt
    12301 tatccaatgg aagtagaaga atataagtac attgtagata aaggtgttga aggattaaca
    12361 gtatatcaag aaacttatga cgaggaaata tataagagag tacatataaa aggcccaaaa
    12421 tcaaattatg aatttagact agatgctcct gaaagagggg caaaagcagg tatgaggact
    12481 ttatcaatag gtgcactttt aggtctaaat gattttagaa aagaaacttt ttttacaata
    12541 ttgcatggga aatacttaaa aacgaaatat cctcatattg agctttcata ttcaacacca
    12601 agaatgagac cttttaaagg gtgttttgag gaattggtag atataagtga tactgattta
    12661 gttcaagcta tggtatgtat gagattattt gaccctcatg cagctataaa tatatccact
    12721 agagaaaatt tagaaatgag aagtcatata atacctttag gagtaactaa attgagcgca
    12781 ggtgtatcta ctgatgtagg aggtcattct caagatgaac atgatactgc tcaatttaag
    12841 ataaatgatg aaagtactgt taaagatgtg gagaaaatgc taaactcaat tggttatcag
    12901 catgtgttta aagattggga aagattttaa atgtatctga taacaaacag aaaattatgt
    12961 agtgaggaac gatatttaga agttattaaa gagtctatat tgagtggtgt agaaaatata
    13021 ataataagag aaaaggattt ggaatatcaa gagctaagaa aattatatat gaaaataaaa
    13081 actaaaatca attgtataga ttttcaagag caaatatcag atgaaagttt gaaaactaat
    13141 ataaatcaaa aagagtgtag aaataaattc aaggttaatt ttataataaa tagtaacatt
    13201 gaattttttg aaaaagtgga ttgtcaaggt atccatcttc cttttaaatt attcttgaat
    13261 ttaattgaaa ataagtataa ttttaatgaa aataaaatac taggattatc tttacataaa
    13321 gtagaggaag tagattattt agaaaaatta ataagaaatc aaaatataaa aatagattac
    13381 ataacattat cacatatata tgaaactaaa tgtaaagaag gattaaatcc aaaaggaatt
    13441 gagcttttaa aagaagctaa aaagattact gatattaaaa taattgcact tgggggaatt
    13501 ttaccatcta atgtcaaaga aacattaaaa tactgcgatg attttgctat aatgtcaact
    13561 ataatgaggt ctaaagatat taaaaaaacc atatcaaatt ataatgaaaa gttgaattag
    13621 taaatatagt atattgaatt tttaacttaa ataaaaataa aaaagttatc ttttaaattt
    13681 taaaaggtag cttttttatt ttatatcttt gctaataaaa aattgtaaaa agggaaaact
    13741 ttagtcagag agattaaaca atatcctaga aagatttaaa atttagtaaa gtatggagga
    13801 cattataatg actgacagta aaaagaaacg atttattata ccacacactt ttacaataat
    13861 atttttacta atagtcttga tggcaatatt gacttggata gtaccaagtg gtgaatttag
    13921 tagagaagat gtagaaggta gaatggtagt tgtaccaggg acttatcaaa gtgtagaaag
    13981 taatcctcaa ggatttgcag atgtttttaa agcaccaata gaaggcttta tagattcagc
    14041 tgaagttgta ggttttgttt taatagttgg aggtgctttt ggtattgtaa ataggactgg
    14101 agctatagaa gcaggaatag cttcggttat ctctaagttt aagggaaaag aacttcttat
    14161 aattccaata tcaatgattt tatttggact tggaggtaca acatttggga tggcagaaga
    14221 gacattacca ttttatatga tatttgttcc actcatgaca tccttgggat atgattctct
    14281 aacagcaata gcaattgtat ttataggagc agcagcagga gccgccgctt caacaataaa
    14341 tccattttca gttggtattg cacaggcact agctcaactt gctcctggtt caggagtaac
    14401 ttacagagta gttattttta tagcatatat actaataagt atagcatttg ttatgtacta
    14461 tgctaagaag gtaaaggaaa atcctgaaag ttcaatagta tatgaaatag ataaaaataa
    14521 taaatcaata cttaatcaaa cttcaacaga aataaaagaa tttactttta aagaagtatc
    14581 tgttcttgct atatttggaa tagggatggc aataatgatt tggggtgttt taagtcaagg
    14641 atggtacatt ccagaaatat caatgtgttt tgctgcaata ggtgtgcttt ctggattggt
    14701 tggtagatta tctcaaattg aaatctcaga aagttttata gatggagcaa aagatttagc
    14761 atctgcagct cttgctatag ctttggctcg tggaatcgta ataattgctc aaaatggatt
    14821 tataatagat actatattaa attccgcagc agcctttcta ggtgggcttc caaaggttat
    14881 atttgtatat ttatcatttt tcttggaagc tgcattggca tttttaattc catcatcttc
    14941 aggtcttgct tcacttacag tacctgtact tgctcctctt ggtgatttgg ttaatatatc
    15001 ggctcaagtg atagtaaccg cttatcaatt tggtgtgggt cttacaaact ttataactcc
    15061 aacttcagga gtactgatgg gagcacttgc agtagcccat attccatttt caaaatgggt
    15121 aagatttata atgcctatct tgttgatttt gacagctgta tctctagtct ttttaacaat
    15181 aggtatttat atagggtttt aattaagtgt agttttattt aagatattta gtaatggtat
    15241 aaaatgataa tatgttttca ataaattgcc actaatttaa ttagtggtaa tttatttttt
    15301 gtatttaaaa ataaatgtat ttacttgtat tttgaattaa tatctactta gacattgttt
    15361 taattgttat attttcattt aattaagcat tgatttatcg ttttttatat ttcatataac
    15421 aatgcaaaaa ataattttta tatagtaaat gacaaaagtt tacaataaat gtatattttc
    15481 ttactcattc cttaaaatta ctcatttagt ttaataactc tcatttcata tgtaaagttg
    15541 gtaaaaaaat taaaattaaa agtaaaaaac taaataaatt aatgttaatt tgaaatatat
    15601 atgaaggttt ttggagaata cttacttatg ataggaaaaa atgttaaaat aatagtgtaa
    15661 tcaaatataa aggactgaaa taattaacag ttattaaata ttaggagtgt aaaaatttat
    15721 gggattaaaa gaatttgatt ttattgaaga gtctattgat atgttgagga caatgtcacc
    15781 aacattagaa actatatcag atgaaataga agagtatttt gaaaatatct tggatgaaaa
    15841 gaatcaagaa tatataaatg taacctctag aataaaatca gaatcaagtt taagagaaaa
    15901 gataattaga aatagatatt taaaaaaata tggagaagca agtaatctta ttcataatgt
    15961 ttctgactta ataggcctaa gaattgagtg tagatttatt gaggatgaaa acaaaatata
    16021 tagacttttg agaagatatt ttaataaaac agatgacaaa ataaactatt ataataaaga
    16081 gaataagaat attaaattaa aactatctga gaggcaaccc aataagcaaa aaaatggatt
    16141 tgaaatatat aaaatagatg gagtttttgc gtatttagat agagaagtaa aatttgaact
    16201 tcaaattaaa tctcttgtaa atgtgttttg gagtgaaata gaacataaaa taatttataa
    16261 aaataataca tatttacttg ctgataaatt tataaaggat atgatggact ctataaagaa
    16321 taatcttact atgatagata atcagctttt aagtatttat aaaaactttc attcagggaa
    16381 gtcttttaat atgaaagtaa gtaaaaaaga aattgaaaaa ttatttgcga aactagtcta
    16441 tgacgctttt tctgaaaaga tgaataaaag tataggtttt gttgtagatt ttaaaaaacc
    16501 atgtgaaact atattgaact attcttttaa taaacaagat ataagtgatg aagttttagg
    16561 taattttatg cttgatgagt ttgcaagatt aaatgaaatt gtaaacaagg atatagattt
    16621 taatgagcaa atagaatttg aaagagaacc aacatttgat gataagtttt gtaaagacct
    16681 aggaaatcat tttagaagta gattaaacac agaatttcca tggaacctat tttttagaat
    16741 attatttgaa atagagccat ataacaatac caaagacttt gaaaactttg tagagtttat
    16801 aaaagaaaat gtgctactag aagaaaatag ggagcaatta ttatgccaat ttgaagaaga
    16861 tagcaagctt ataattgaag atatatatga ttgtatattt aatagtataa gtgagattga
    16921 tagtgttgaa attttatata actataatct tgaaaaaata aactttacat caagtgaaat
    16981 cataaattgt atatgtagag aatatgagtg ttatggtgaa tacttagaag aaaaagaaaa
    17041 gcttatgaat acatttaaag aaaagattat tcaaatcttt gagtaatagg tcaatgctga
    17101 agtggcgcta atgcgccatt tttcaaatat atatgaatta agtaaaatta ttttggagga
    17161 ggcgatttgt atagagaaaa caggtgtaat tttggcaggg ggaaaaaatt ctagaatggg
    17221 tagagataaa gcctttttag agttacatga taagcttttt attgaaattg caatagaagc
    17281 atttaaaaac tttgatgagt tgataataat atctaataat gaagaattat attctaaata
    17341 cgatattaaa gtttataatg atatagtaaa agatgttggt ccaattggag gaatatatac
    17401 tgctcttgaa tatgcaaagt atgatatagt tacaattgca tgtgatatgc catatctaaa
    17461 taatcaaata gtcgaaagaa tagctaataa aatgaatgat aaaagtgtga tttcagtgac
    17521 aaatggaaag ttacaaccat tgtgttctgg atataaaaag agtataataa ataaagtatc
    17581 tttatgtata agggaaaatg atttaaagct cagaagcttt atagataaaa tagataaaag
    17641 ttatatatac tttgatgaag aagatttatt tttaaatgta aacactgttg atgagtatga
    17701 aaaattaact aaagtttaat tagctatggt tgtaaaatag agtaggattt atatggagga
    17761 gagtttatga atttacttaa atgcgattct tgggcagtaa tattaaataa tagcgataaa
    17821 gaaagtaaag catataaaat attagatgaa cttaaaagga atatgtacaa agttgttgct
    17881 atagatgaag agaaaaaacc tattgaagga atagatgtgt atgaatgttt aaaagatgtt
    17941 ccacacaata ttgatgttgt agctattatt gataaacaat ctaagatgga tgtgatttta
    18001 gaagaagtag agcttttgga tatacaaaat atgtggtttg aaaaaggaag ctttagtgaa
    18061 atgatgatta aaaagactaa agatttaaaa ttaaatatag aatataattt aagtttatat
    18121 gatgagttga ctagataaaa ttatatttct taataataaa aatataatta gttaataaaa
    18181 catattattt tatagtatag attggttaat aaaagtacag attggttaat gaaacattaa
    18241 attacaatat ttgttaaaag aattgtgagt tacatgatat aatgtattaa ataggatact
    18301 aaggagttga tatattatgt taatagtaac tacagaaaaa gtagaaggta aaaagatatc
    18361 aaaggtttta ggattagtga gaggaagtac aataagagca aaacatgttg gaaaagatat
    18421 aggagcaagt tttaagaatc ttgttggagg agaacttact ggatataatg aaatgctcac
    18481 tgaagcaaga caaattgcca taggtagaat ggttgaagat gcagaagcta aaggtgcaaa
    18541 cgcagtaata gcatttagac tgtcttcagc ttcagttatg caaggggcag cagaaatgct
    18601 tgcttatgga acagcagttg ttttagaaga tgataatagt attcttgaaa aataaaatat
    18661 aaatagttaa aaagaggcat cttttaaaaa ttttatggat gccttttttt atttgaaaaa
    18721 actaatttga gaagaaattt taactattat gacaataaaa ttagggtgat attatataaa
    18781 taagtaaaat tatattatat aatgtatggt atagacttta aaaattttat ttgtagagaa
    18841 aaatatggac aatgttataa taattataga aattaaaagt acttacattc attatgtatg
    18901 tgacatgtat aattagtttt atatttaata cagttttgaa gtaatatctt cattttgaga
    18961 acgttggaat aataaaaaat gtatgtatta taggtgatat aaataaaaaa taaatataat
    19021 atgttatatt gctgatagaa aagagaataa aagaaaatag gttttattaa aagagatttt
    19081 tatttatagg acttaatcaa tgtatagagg ggtgagaaca tatgtttaat gttgcaatta
    19141 taacacttag tgataaagga tatgaaggaa aaagagaaga tataacagga aaaaagttaa
    19201 ctgaatttgt tgaaaataca ggagcttata aagttactga gtatgtactt ataaaagatg
    19261 ataaggaaat gctaaaggaa aatattataa gactttgtaa tagtaataaa atagatttaa
    19321 ttcttacaaa tggaggtact ggtttttcaa aaagagatat aaccccagaa gcaactaagg
    19381 aagtgttgga aaaagaaata ccaggtctga gcgaatatat gagaatgaaa tccacagaaa
    19441 ttactaaaaa ggccatacta agtaggggtg tgagtggaat aagaaataat tctataataa
    19501 taaatttacc tggaagtcct aaaggtgcag ttgaaaatct aagttttata attgatgttt
    19561 tagaccatgg catagaagtt ttaagaggag aagctacaga atgtgccact aaaaaaagtg
    19621 aatagtatat aatctagata gataaaaaat agacaaagag gtagataaag tatgattgat
    19681 aagtatggaa gaaaaataga ctaccttcgt atttcactta cagataagtg taatttaagg
    19741 tgtgtctatt gtatgccacc agatgtaaaa tttgataaaa attatataaa tgaaaatcta
    19801 agctttgaag actacaagtt tattataaag gctatggctg aacaaggtat aacaaaaatt
    19861 agatttactg gaggagaacc tcttttatat cctaaattaa atgagcttat aaaatttaca
    19921 aaagaagaat gtggaataaa taacatagga atgactacta atgctattgg gctttctgat
    19981 agaatttttg agcttgaaaa atgtggctta aataaagtta atataagttt agattctttg
    20041 aaggaatata agtataaatc cgtaacaaga ggaggaaact taaaagatgt cttaaaatcg
    20101 attgaatctt gtttaaactt aggtataaaa gtaaagttaa attgcgttgc tataagtggg
    20161 tttaatgatg atgagcttaa agattttatg tttttaacag ttaaatcacc aattgatgta
    20221 agatttatag agcttatgcc attaggtgag gctaatagag tttataagaa gggttatttt
    20281 aatgtaaaag aaatgattga aaaaatatat ggtttatata aagtcaaaaa tgatgaaaaa
    20341 agtacagcag aatattatat gtttaaagga gctaaaggaa gaataggaat tataactcca
    20401 ttaagctgtt cattttgtaa cacttgtaat cgtattagac ttacttctag tggtgcaata
    20461 aaattatgtc tacattcaaa agaagaaata gatataaaac catttttaca taaaccattg
    20521 ttatttagag aatctatgaa agatataata aaacaaaaac cagaaaaaca tcatttaata
    20581 gaaaataaat gtagtgatac aaataggcgt atgtatgaaa ttggaggata agtaatgtta
    20641 acacatataa atgaaaaagg gtatgccaag atggtggaca taagtgaaaa agatgatact
    20701 aaaagaacgg ccgtagctac agctacaatt actcttagta aggaagcatt agaaaaagta
    20761 aaaaatggtc agataaaaaa aggagacgta ttgtctgtag ctcaagttgc aggtataatg
    20821 ggagctaaaa atacatcttc aaacatacca atgtgccatc agattaaatt agttggatgt
    20881 gatttagaat ttgatgtaga tgattatatg tctgctatta agatatacgc aacctgtaaa
    20941 tctcttggga aaactggagt agaaatggaa gctttaaatg catgttcttt agcagcactt
    21001 acaatttatg atatgtgtaa agcagttgat aaaaaaatgg ttataagtaa tatccatctt
    21061 gtggagaaga ctggtggaaa atcaggagat tttaagttcg agtaaattaa taatatattg
    21121 ggttaaaatt tggaggaaat atggcgaagg tagtgtcaat aaatataagt gagaaaaagg
    21181 gtgtaattaa agttcctgta ccatgtgcag agctaaaaat aaatcatggg atagttggag
    21241 atgcacatgc aggaaactgg catcgtcaga taagcttact tggaaaagaa agcatagata
    21301 aaatgaaaat gaaaggcttt gaccaattaa aatatggaga ttttgctgaa aatgtaacta
    21361 cagaagggat agaagttttt tccctgcctg ttggtacaaa gttaagaata gggcaatgtg
    21421 aagttgaagt aactcaaata gggaaaaaat gtcacaatgg atgtgaaatt aagaaattga
    21481 caggtgactg tgtgatgcca cgagaaggaa tttttgtaaa ggttctaaaa gaaggaatta
    21541 taaatgtgaa tgattcaata gatgtaatct aatgaagtca ctattaaaat ataat
//
LOCUS       DAMJWO010000074        21245 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.075, whole genome shotgun sequence.
ACCESSION   DAMJWO010000074 DAMJWO010000000
VERSION     DAMJWO010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21245
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.075"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            270..791
                     /locus_tag="PC366_002814"
     CDS             270..791
                     /locus_tag="PC366_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2578311.1"
                     /translation="MDIAKLILNPARLRILQYIRLHGSARTSDIVKYLNDIPRATVYH
                     HVKILEENNMIEVIKENRVRGTIEKVYALKEYTTSMEGETFVALSTAFYVGLMQEMNE
                     YFSRKEQDHKKDNVFFSSALLYMSDNEYENLLKSIADLLKPYIEQKPKSNLKLRKLSI
                     ISSPPVVDNDKTK"
     gene            825..1601
                     /locus_tag="PC366_002815"
     CDS             825..1601
                     /locus_tag="PC366_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2578312.1"
                     /translation="MKFHEFGDKNKPHIMLIHGGGNAWWNYLRQAEVLSNNYHVILPT
                     LDGHGEEYETTYISTEDTADKLISYIDENCSGHLFALCGVSLGGQIVMELLSRKPNIT
                     KKAIIDGSICYPRPLMARFCIAGIRFFGGLLFSEKACRFQIAMMPKLLPENMQYPDEI
                     KAYYMTDMPHVRKETFYNMYRTYMMNYTLKENVKKTTAQVMYWYGEKEMKCVKKSAKM
                     FQSYVPSCEIYEAKGYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            1944..2897
                     /locus_tag="PC366_002816"
     CDS             1944..2897
                     /locus_tag="PC366_002816"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HDF2578313.1"
                     /translation="MINVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDRQGAEIMNKDIGKYITLESNLMKFDDDESREEMISYLKEELVDIFGQDKNKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            2915..3934
                     /locus_tag="PC366_002817"
     CDS             2915..3934
                     /locus_tag="PC366_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HDF2578314.1"
                     /translation="MFKKCIKVVTLTFILACILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTENKKNNKNKETSKENKEESKEENTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNTTSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            3965..4216
                     /locus_tag="PC366_002818"
     CDS             3965..4216
                     /locus_tag="PC366_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578315.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRILFLITMIIGTSVCVFIVDSNA
                     KSMLGMKQYDFPSIKFDITKFDFDIPNFDIHEIIKKFNK"
     gene            4498..6303
                     /gene="lepA"
                     /locus_tag="PC366_002819"
     CDS             4498..6303
                     /gene="lepA"
                     /locus_tag="PC366_002819"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HDF2578316.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDERRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            6454..7791
                     /locus_tag="PC366_002820"
     CDS             6454..7791
                     /locus_tag="PC366_002820"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HDF2578317.1"
                     /translation="MINIEIPKKVDYIIKELETNGYEAYVVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMIEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSKTGLVDPFNGYEDIQNKYIRCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFKIAEGTKQSIHKKADLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLISTEVIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILRRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVELFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGHILNKMLEIVINNPELNEKEILKEKALNIYTF"
     gene            8024..9337
                     /locus_tag="PC366_002821"
     CDS             8024..9337
                     /locus_tag="PC366_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2578318.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIVFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITVGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKTLLKVNSGGSPVNSI
                     LLITVLACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLHRPYKVPLYP
                     IIPIIAILGGLFVIINQILTSTIISLGGIFITLLGLPVYYYMKKR"
     gene            9509..10684
                     /locus_tag="PC366_002822"
     CDS             9509..10684
                     /locus_tag="PC366_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HDF2578319.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDSKKRYIEDLKIEMKLY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFISIKEMFDIDEN
                     AEITIECNPGTLTLEKLKTMKEIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINVDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENVDIEMYEYTINYLKSKGYNQYEISNYSKEGYNCEHNILYWECEHYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFREKYNKQIEMLLARKLINQSFEGIQLTQKGREISNSVFIEFME"
     gene            10787..11806
                     /gene="hrcA"
                     /locus_tag="PC366_002823"
     CDS             10787..11806
                     /gene="hrcA"
                     /locus_tag="PC366_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="HDF2578320.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            11836..12456
                     /gene="grpE"
                     /locus_tag="PC366_002824"
     CDS             11836..12456
                     /gene="grpE"
                     /locus_tag="PC366_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HDF2578321.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSSEKT
                     DEKEVDDENVTDINSKLAEKKLQDELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGVEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            12548..14395
                     /gene="dnaK"
                     /locus_tag="PC366_002825"
     CDS             12548..14395
                     /gene="dnaK"
                     /locus_tag="PC366_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HDF2578322.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLADEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSEAEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSGEKEDIEKAIADLKAVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            14606..15760
                     /gene="dnaJ"
                     /locus_tag="PC366_002826"
     CDS             14606..15760
                     /gene="dnaJ"
                     /locus_tag="PC366_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HDF2578323.1"
                     /translation="MSTKRDYYEVLGISKDAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRARRRGPQRGADIRQSVTISFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSACNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            16726..17661
                     /locus_tag="PC366_002827"
     CDS             16726..17661
                     /locus_tag="PC366_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDF2578324.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKRRFPD
                     AEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKDYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EDLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            17697..19070
                     /locus_tag="PC366_002828"
     CDS             17697..19070
                     /locus_tag="PC366_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2578325.1"
                     /translation="MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEGNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
     gene            complement(19258..20025)
                     /locus_tag="PC366_002829"
     CDS             complement(19258..20025)
                     /locus_tag="PC366_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2578326.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNAIYVIDF
                     LDKNNLDNLKGNFYLIYQSHIDFEYLKNIFYNLFEDINIIQHNGFFIVNSKYNLDINV
                     TTQNIIETETYQSTYIFYLGELDSKADFYFRLQLCSDLLPHIIKDNAENKFLNLFDLI
                     RYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGIKFINNDLNISKTSTSMFLHRNTL
                     VYRLEKINEILGFDLKNFENAMIFYLSVKSYFLYKKI"
     gene            complement(20055..21164)
                     /gene="ugpC"
                     /locus_tag="PC366_002830"
     CDS             complement(20055..21164)
                     /gene="ugpC"
                     /locus_tag="PC366_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HDF2578327.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNDIEPKDRDIAMVFQNYALYPHLSVYENMAFALK
                     LRKLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDKIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRVHIFDKETTLAIR"
BASE COUNT         8301 a         2398 c         3748 g         6798 t
ORIGIN      
        1 aatgaaaaat tataaaaata taaatttata tgcttaatta agataatttt tccaataatc
       61 aagataattt ttttcattag tatgtatgat agatgcatca aacaatataa ctaatatgtt
      121 agaaggttat atgtaattaa tctcagtgtt tatatagaat agcatttgta gcatttatta
      181 tagttgtaat tactacttat atcatagact tgaatagtct aaaaaaatag actataatat
      241 ttttatagac taaagaaagg gctgataaga tggacatagc aaaactaatt ttaaatcctg
      301 caaggcttcg tatcttacaa tatattcgac ttcatggcag tgctcgcaca tctgatattg
      361 taaagtattt aaatgatatt cctcgtgcaa cagtttatca ccatgtaaaa attttagaag
      421 agaacaatat gattgaagta attaaagaaa atcgtgtgcg tggtactatt gaaaaggttt
      481 atgcactaaa ggaatataca acatctatgg aaggagagac cttcgttgca ctttctacag
      541 cattttatgt aggtctgatg caggaaatga atgaatactt tagcagaaaa gagcaagacc
      601 ataaaaagga taatgtattt ttctcttcag cattactata tatgagtgat aatgaatatg
      661 aaaatcttct taaaagtata gctgatttat tgaaaccata tatagaacaa aagcctaaat
      721 caaatctaaa acttagaaaa ctttcaatta tatcttctcc acctgtggtt gataatgata
      781 aaacaaaata acatgaatct tatttttata aaaggaggtt gtatatgaaa tttcatgaat
      841 ttggagataa aaacaaacca catattatgt tgattcatgg gggagggaat gcgtggtgga
      901 actatttgcg acaagcagaa gttttgtcta acaactatca tgtgatactt cctacattgg
      961 atggtcatgg agaagaatat gaaacaacat acatttctac agaggataca gcagataagt
     1021 tgatatcata tatagatgaa aattgcagtg gacatctttt cgctttgtgt ggggtatcac
     1081 ttggtggtca aattgtcatg gaacttttat ctcgaaaacc taatattact aaaaaagcaa
     1141 ttattgatgg tagtatttgc tacccaagac ctcttatggc aaggttttgt attgctggta
     1201 ttcgattttt tggaggactt ttgtttagtg agaaggcttg tcgctttcaa attgctatga
     1261 tgccaaaatt gttacctgaa aatatgcaat atccagatga aataaaagcg tattatatga
     1321 cagatatgcc acatgtaaga aaagaaacat tctataatat gtatcgtact tatatgatga
     1381 actatacact taaagagaat gttaaaaaaa ccacagcaca agtaatgtac tggtatggag
     1441 aaaaagaaat gaagtgcgtt aaaaaatctg caaaaatgtt tcagtcttat gtaccctctt
     1501 gtgagattta tgaagctaag ggctataatc atgggtattt atcgctttat cttccaaatg
     1561 aatggttgga aattgcagaa ccatttttcc aaaaggaata aaggtgttag gtgattattg
     1621 tataattatt gctgtttttt tatatagtaa ataaattagg tataaatata aaaaagttat
     1681 tttagttaat atattagtga aagcttaata ggaaaattat aaatagatta aaggtagcgc
     1741 ctatataaat agttgctacc tttttttgct tgtaaataaa tgatagataa gaaagtttac
     1801 tgacaaatca ctgactaaac ccaattttct tacattgaaa gccttaattt tacttgtttt
     1861 aaataaattt acaatttctt gttataaaat actaaatttt gttaacaatt ataattagca
     1921 tttaatttat actggaggtt tatatgatta atgtaagaac agatttagct ttagaagcta
     1981 gtgaaatgtg tgaaaagtct caagaaggaa gtagtattcc tggtgtaaaa atagaaacta
     2041 aagaattaga aaattgcatt gtaactaaag ttgaagtaat agacaggcaa ggcgcagaga
     2101 taatgaataa agatatagga aagtatataa ctctggaaag taatcttatg aagtttgatg
     2161 atgatgagtc gagagaagaa atgataagtt atttaaaaga ggagttagta gatatatttg
     2221 gccaagacaa aaataaaaaa accctggtaa ttggtcttgg aaatagaaat attacttctg
     2281 atgcgttagg accaaagagt gtatcaaaaa cacttgtaac tagacatctt tttaaaaatt
     2341 ataataaaga ctatgatgat gatttcactg aggtatcagc tttaagccca ggagttatgg
     2401 gtgttactgg aatagaaact agtgaaatag taaagtcatt ggttgaaaaa gtaaaaccag
     2461 atagagtagt agcaatagac gcattggctt caagaaaaat ggaaagagta aactctacta
     2521 tacagatatc aacagcagga atatcacctg gtggaggtgt tggcaatact agaaaatctc
     2581 taactaaaga aactttaggc gtggatgtta ttgcaatagg cgttccaacg gtggttgatg
     2641 cagcaactct tacaatagat gtcttagata tggcaataga caatttaata gctcaatcag
     2701 aagaaacaga aagtttttat gaaatgttga aaaaacttaa agaagaagaa aaatatcatc
     2761 taataaaaga ttcgttagac ccatatgaca agaacttaat agtaacacca aaggatatag
     2821 atgatacaat cgaaaatcta tctataataa taagtgaagg cttaaatagg tctttacatc
     2881 caggtagatt ggtataaaat aaggaggagc aattatgttt aaaaaatgca ttaaagtagt
     2941 aaccttgact tttatattag catgcatttt accaggaaaa tcattagctt tgaatcagga
     3001 tgatttttta aagtttttag taaattcatc ttatccagaa gctaaagtcg aaggaaatga
     3061 tacagaaaat aaaaagaata ataaaaataa agaaacaagc aaagaaaata aggaagaaag
     3121 taaagaagaa aacactaaat ctaaagatgc aagtaaagtt gataataaaa aagagagtga
     3181 aaaagaatat ataaaacttt atgttggtaa agaaaatgtt ccagatattg agtcaaaaaa
     3241 ttcagacaca actgaaacta acacaacatc tagttcagat tataaggatg atttaagagt
     3301 aaccaaagaa aatccaagaa ttttgatata tcatactcat ggatgtgaga cttattcaaa
     3361 ttcacctgat ggaaattatc attcaagaga taagaaaaat tcagtaatgg aagtaggaag
     3421 tgcattaact agtgctttag atagcaaagg atggggtgta gtccatacta ctaaatacca
     3481 tgactatcca tcttataata actcttatgc aagtagctta aaaacaatac aaagtatatt
     3541 acctaaatat aactcagtgg atatagcgat agacttacat agagatgcta gggatttaac
     3601 taatccagcc actaaggaaa aagaccattt aaaatataca actatgataa atggagagag
     3661 agtatcaaag ttcttctttg ttgtaggagg taaaaataca aatagaaaac aacttagagc
     3721 tttagcagaa gatataactg cttttgctga gaaaaagtat cctggtctag tatctccaat
     3781 agtagaaaaa gactatgcta gattcaatca gtttgcagtt aagaatcata tgttagtaga
     3841 aatagggaat aacgcaacaa gtgtagaaga atctaaggct actacaaagt atttagccga
     3901 gattttagat gaatatttta aacaaaaaaa ttagagcttt aagttataat taggagcatg
     3961 ctaaatgagc cgattagaaa aaaatataga aagtaaaagt aaactaagaa aatacaagta
     4021 tattatgaga atcttatttt tgattactat gattataggt acatcagttt gtgtatttat
     4081 agtagacagt aatgcaaaaa gtatgctagg aatgaaacaa tatgattttc caagtattaa
     4141 atttgatata acaaaatttg attttgacat accaaatttt gatatacatg aaatcataaa
     4201 aaaatttaat aagtagtaat aagtgaataa ggtttattga ttaaaataag ccttatttta
     4261 gttatatatt tttaatgtat aaaataaaaa ttcattaact gtattttata ggatttactt
     4321 taagtttacg atattatata atatttagtg ttagacttga taatccacat ataatgtgga
     4381 taattttgtt tagtgccaat tagtttatat tcaaaaattt taaatttggt atataaagag
     4441 tttttagata atgtaaaata ataactataa gaataatcaa gaggagggaa ttttaaggtg
     4501 gacaataaac aaagtagaac tagaaatttt agtataattg cacatataga ccatggaaag
     4561 tctaccttag ctgatagatt aatacaacaa actgggcttg ttagtgaaag agacatgaaa
     4621 agtcaattac ttgacaatat ggaccttgaa agagaaagag gaatcactat aaagcttcaa
     4681 aacataagat taatgtataa agcgaaggat ggaaatgaat attatttaaa tcttatagat
     4741 acacctggac atgtagactt taactatgag gtatcaagaa gtttagctgc atgtgaagga
     4801 gcactattag tagttgatgc agctcaaggt gttgaggcac aaactttagc caatgtttat
     4861 cttgctatag accaagattt agaaatatta ccaataataa ataaaataga tttaccaagt
     4921 gcaagaccag aggaagtaaa aaatgaaata gaagatttaa tagggcttga ttcaagtgaa
     4981 gctcctctta tttcagctaa aactggttta aacatagaag atgttttaga agatattgta
     5041 aaaaatgttc ctccacctaa gggagataat gaagctccat taaaggcatt aatattcgat
     5101 tcttactatg atgcttacaa aggtgttgta gcttatgtta gagtatttga aggaactgtt
     5161 aaaaagggta tgacaataaa aatgatgaat accaataaaa agtttgaggt aactgaagtt
     5221 ggtgttatgg ctccaggtca aactgaactt agtgaattat cagcaggtga tgttggttat
     5281 attgctgcta gtataaaaga tataagaagt tgtcgtgttg gtgatacaat aacagattca
     5341 aataatccta cagaagaacc tttaccagga tacaaaaaag ctactccaat ggtatattgt
     5401 ggtatatatc caggagaagg agaaaagtat gagaatgtta gagatgctct tgaaaagctt
     5461 caagtaaatg atgctgcact tgaatatgaa gctgagactt cagcagcact aggatttggt
     5521 tttagatgtg gtttcttagg tcttttacat atggagataa tgcaagaaag acttgagaga
     5581 gaatttaacc ttgatataat tactacagct ccatctgtta tatatagagt tacaaaaatg
     5641 gatggagagg ttgtaatgat acaaaatcct gcaaacttac cagaaccatc tgagataaag
     5701 atgatagaag agcctatagt aaaaggagat ataatagttc ctaaagacta tgtgggtgtt
     5761 gttatggagc tttgccagga aagacgtgga aatatgttaa atatggaata tatagatgag
     5821 agaagagtaa tgcttcacta tgaccttcct ctcaatgaag ttgtttacga tttctttgat
     5881 gctttaaaat cgagaactag aggttatggt tctcttgatt atgaggttaa aggttatgta
     5941 gcatctacac ttgtaaaact tgatatatta atcaataaag aacaagtgga tgcacttagt
     6001 tttattgtcc atgagacacg tgctttccct agaggaaagg caatgtgtga gaaattaaaa
     6061 ggagaaattc caagacatca gtttgctata cctatacaag ctgctgttgg taataaggtt
     6121 attgcaagag aaacaataag cgctctaaga aaagatgttc ttgctaaatg ttatggtggg
     6181 gatatatctc gtaagaagaa acttcttgaa aagcaaaaag aaggtaagaa gcgtatgaga
     6241 caaattggtt ctgttgaagt tcctcaaaaa gcatttatgt ctgtacttaa actagatgaa
     6301 taaattctta taaatttaga taaatatatt taaaagctag agtgatttta gaattatttc
     6361 taaattaatc tagctttttt gtggtatatt ttaagtaaac tcatagagaa tataagtaag
     6421 aatatattaa agaagaataa aaaggtgata tttatgatta atatagaaat tcctaaaaaa
     6481 gtagactata taattaaaga attagaaacg aatggttatg aagcttatgt agttggagga
     6541 tgcgttagag attgtttatt agaaagagtt ccaaacgatt gggatataac aactagtgct
     6601 agaccagaag tggtagtaga attatttgaa aaaacaattc caactggtat acaacatggg
     6661 actgtaacag ttatgattga acatgaacca tttgaagtga caacttatag aattgatgga
     6721 aattatagtg atggtagaca tccagattca atagaattta caaataacat agttaaggac
     6781 ttgtcaagaa gagattttac tatcaattca attgcataca attcaaagac aggattagtc
     6841 gacccattta atggctatga agatatacaa aataagtata tacgttgtgt tggaaatcca
     6901 gtagatagat ttgaagaaga tgcacttaga atgcttaggg cagttagatt ttcagcacaa
     6961 cttaatttta aaatagctga aggtactaag caaagtattc ataaaaaagc agatttgata
     7021 aaaaatgttt ctatcgaaag aatccagaca gagtttaata aaatattagt atctgattca
     7081 tctaaattaa acttattaaa atcaacaggt ttgttgaaat ttataattcc tgaaatatgt
     7141 gaattagaag atgttactca acacaatcca tatcacatct atgatgtaca aaaacatact
     7201 ttaatatcta cagaagtaat tgaagatgaa ctgtatttaa aacttacaat gttgtttcat
     7261 gatttaggta aaaaagtaac taaaacaact gataaaaatg gtgttgacca tttttatact
     7321 catagtagag aatctgtaaa gattgcaaag aagattttga gaagacttaa gtatgataat
     7381 tatactatta ataaagtttt aatattaata caatatcatg attatagaat agaacctaaa
     7441 aggaagataa ttaaaaagtt attaaataaa cttgaagatg ttgaattatt tgaagattta
     7501 ataaaagtta attgggctga tacacttgcc aaaaacccaa agtatgcaaa acaaaagata
     7561 ttaaatctta ttgagtgtga aaaagaattt aaacatataa taaatcaaaa ggagtgcttt
     7621 aatcttaaag atttagctat taatggaaaa gatttgatat ctataggtat aaaaccaggt
     7681 aaagatatag gacatatttt aaataagatg cttgaaatag tcataaataa tccagaatta
     7741 aatgaaaaag aaatactaaa agaaaaagca ttaaatatat atacatttta gattcaaata
     7801 taaaaaattt aattacttta aaaaattata gaagaaaata cttatttaga taaaataaat
     7861 aatttttaga gaatatttta gaagttacga ttgtatgatt tttaaacgca tagcatttac
     7921 tctaggacta tagactaata taaaaaaaaa ctttgggaat actaaaacca taaatttata
     7981 aaattaatat tttatatact gtaaaacagt gaggagggac agtatgcata ctcaactaca
     8041 aaagactatt ggtctttcag cggctctttc tactgttgta ggtatggtta taggttcggg
     8101 agtttttttt aagccacaag caatatacac tacaactaat ggagctccag gtctaggtat
     8161 tatagcgtgg cttttaggtg gttttataac aataactgct gggcttacag ctacagaaat
     8221 ttcagctgct ataccaaaaa ctggtggtat gatgatttat atcgaagaaa tatatggaga
     8281 aaagttaggc tttttaactg gatggatgca aactgtatta tttttcccag gtacatcagc
     8341 agcattagga gtaatatttg ctcaacaagc atctgaactt ttaggaatga gcccaaataa
     8401 tatggcaaat gtacttccta tagcaattgg agttatacta tttttagcgt tattaaatat
     8461 aataggttca tccttaggag gaaaagttca gacagtagcc actattggaa agatgatacc
     8521 tttaatttta ataatagtct ttggatttat taaaggtcaa agtagtgaag tattaaatcc
     8581 atttgtagga gatggtgtaa atgcatcaaa tgcacttgga caagtattaa tagctacttt
     8641 gtttgcatat gatggttgga taaatgttgg agctatatca ggagaaatga agtctccaga
     8701 gaaagattta ccaagagcaa tagttggtgg tttatcatta gttatggcag tttatattat
     8761 aataaatata gcttatcttt gggtagtacc agcaagtgaa ttagcaacag ttacttcccc
     8821 agctacatta gtagcaacaa gattgtttgg aaatataggt ggaaaagtaa taactgtggg
     8881 tatattaata tcagtatttg ggacattgaa tggatattta ttaacaggtt caaggatacc
     8941 ttatacatta gctgaaatgg gaactttacc agcatctaaa actcttttaa aagtaaattc
     9001 tggaggttct cctgtaaatt caatactact tataactgtg ttagcctgtg tatatgcatt
     9061 atctggtcaa tttaatcttt tgacagactt aactatattt tcaatatggg tattttatgt
     9121 attgactttt ataggtgtta tgaggcttag aagacaaaag ccagatttac acagaccata
     9181 taaagtccct ttatatccaa taataccaat tatagctata ctaggtggac tgtttgtaat
     9241 aataaatcaa atattgactt caacaattat atctttaggt ggaatattta taacactatt
     9301 aggtttacca gtttattatt atatgaaaaa aagataacta cttaatttaa gttagataaa
     9361 tttgggtaaa ggtgaaaatt aacttttatc caaatttttt atactgttat acaatataag
     9421 cattatatat tacttgatgt gttattttgt ttgatttata atttagtaat tgatgcttta
     9481 agataattta agaaatgagg aataaaaaat gctaggactt tatgtacata ttccattttg
     9541 tgtgaaaaaa tgtaagtatt gtgattttaa ttcttataaa atggacatag attcaaaaaa
     9601 aagatatata gaagacttaa aaatagaaat gaaattatat agtaataaat tatataaaga
     9661 taataaatat aaaaataaag aatgctgtag tctaaataaa aatgacaaaa taacgagtat
     9721 atttgtaggg ggaggtacac ctagtatact aacatctgat gaaataagag aagtatttat
     9781 aagtataaaa gaaatgtttg atatagatga gaatgcagaa ataactatag agtgtaatcc
     9841 tgggacatta acattagaaa aattaaaaac tatgaaagag attggcataa atagacttag
     9901 tatagggcta caggccattc aagaaaagca tttgaatttt ataggaagaa tacatactta
     9961 tgaagaattt gagaaaaact ataaagatgc attaagtgta ggttttaaaa atattaatgt
    10021 agatttaatg tacagtcttc caaatcaaac tctatgtgac tggaaggaaa ctcttgaaaa
    10081 agttgtacac ttaaatccaa cacatatatc agcgtattcc cttatactag aagaaggaac
    10141 tgaactatat aatatgtatg aaagtaataa atttgagctt atagatgaaa atgtagatat
    10201 agaaatgtat gagtatacaa taaactactt aaagtcaaaa ggatataatc aatatgaaat
    10261 atcaaattac tcaaaagaag gctataattg tgagcataat attttatatt gggaatgtga
    10321 acattatata gggattggag caggagcttc tggctatatt aatgagaaca gatacaataa
    10381 tgtagaatct ttagaagatt atcatttaag tttggtaaaa agagaaaaac caatacaaga
    10441 aaatgaaatt ctttctgaga aagatatgat agaagaaaag atatttatgg ggcttagaat
    10501 gaataaaggc ataaaatttg aagattttaa aaaaaaattt ggaatagatt ttagagagaa
    10561 gtataataag caaatagaaa tgctattagc tagaaagctt ataaatcaga gctttgaagg
    10621 tatacaatta actcaaaaag gaagagaaat atctaatagt gtatttatag aatttatgga
    10681 ataattttta aggtgttgac aaaataaatt tataatggta tataatatat ataatctttt
    10741 tagcactcga acttagtgag tgctaacagc taggaggtat aataatatgg aattaaatga
    10801 aagaaaatta aatatcctca aagctatagt taaagattat atagaaacag ctgaagctat
    10861 aggttctaga acaatatcta aaagacatga tttaggtgtt agtgctgcta ccataagaaa
    10921 tgaaatggct gaccttgaag aattagggta tttaattcag cctcatactt ctgcgggtag
    10981 agttccatct gaaaaaggct ataagttata tgtaaactct cttatgagta aaagcgaatt
    11041 ggatgataat gataagattc ttattgaaca atgtatgaat cataatataa atcatataaa
    11101 agaattgatt catgaaacct ctaagctatt atcgcaacta acaaactata caactgtagc
    11161 agttactaag agtttaataa atcaaagtgt tataaagcac atacagttgg ttgctatgaa
    11221 tgacaataat attttactta tagttgtaac agataaaggg gacttaaaaa aagctaacct
    11281 tacaactaat gtatatttag atcaatctaa gttaaatttg atttctgata atcttacaag
    11341 gaagctttta ggtaaaagta taacagattt ggatgataat ctaattgctt ttattaaata
    11401 cgaaataagt gagtattctg gacttataga tgagctttta aatgctttga actcaaatat
    11461 gaaagaagaa gatttttctc tatcattaaa tggagctact aacatattta gttatccaga
    11521 atttaatgat gtattaaaag caaagtcatt tttaaatatg ttggaaaaaa aggaaacaat
    11581 agctgacata attaaatcaa agggaataca aaaagacaat ctaaatataa taattggtag
    11641 tgataatgat tgtgaactgg cacaggattg tagtatagtt acagcaactt ataatgtaga
    11701 tagagacttg gttgggcgaa taagctttat aggccctacc agaatggatt atgctagaat
    11761 ttactctata ataaattata tgagtttatt aattaataga aagtaaagaa attttaaatt
    11821 gcgaggtgta aagtcttgga taaaaaaaat gagcaacagg aagtaagaga agaaaatgat
    11881 acttctatta accaagaatc ggaaactcaa gtagagttag aagaggaagt tgttaatgaa
    11941 gaatgtgaaa catcaagtga aaaaactgat gaaaaagaag ttgatgatga aaatgtaaca
    12001 gatataaatt ctaagttagc agaaaaaaaa ttgcaggatg agttggatga attaaatgat
    12061 aaatatcaaa gacttcaagc cgaatatgca aactacagaa gaagaactca acaagagaaa
    12121 gagacaatag gcgtatttgc aaatgaaaaa ataataactg agttgatacc agttatagat
    12181 agtatggaaa gagccttaga tgcatgtgaa gataaggaag atactatgta taagggtata
    12241 agccttgtac ataaacaatt aatagacact ttggtaaaat ttggagtaga agaaatagaa
    12301 gcagaatcta aggaatttga ccctaatcta catctagcag ttatgcaaga aagtgtagat
    12361 ggagttgaag caaatcaaat agtaatggta cttcaaaaag gatataagct aggaactaaa
    12421 gttgtaagac cttcaatggt taaagtttct tgctaagtat aaattaaagg ttaaattatt
    12481 taacctaata taaaatatta aaataagtaa aacttaatta tataattact cgaggaggat
    12541 tttagtcatg ggaaaaataa taggaataga tttaggaaca acaaattcat gtgttgcagt
    12601 gttagaaggt ggagaagcac aaataatagc aaatagtgaa ggtatgagaa ctactccatc
    12661 agtagtagca tttacaaaag atggtgagag aatagttgga gaacctgcaa aaagacaagc
    12721 agttacaaat gcagataaaa caataacttc tataaaaact catatgggaa ctgattataa
    12781 agtaaatata gatggaaaat catatactcc acaagaaata tcagcaataa tattacaaaa
    12841 attaaaatca gatgcagaaa gttacttagg acaaacagta acagaagcag ttataacagt
    12901 accagcttac tttacagatg ctcaaagaca agcgactaaa gatgctggta gaatagcagg
    12961 gcttgatgtt aagagaataa taaatgagcc aacagcagca gctcttgctt atggtatgga
    13021 taaattagac caagaaaaga aaatattagt atttgactta ggtggaggaa cttttgacgt
    13081 atctatactt gaaataggag atggaacttt tgaagtttta gctacagctg gtaacaatag
    13141 attaggtgga gatgactttg accaaatagt aatagattat ttagcagatg aatttaaaaa
    13201 agctgaaggt gtagatttaa gaaatgataa aatggctctt caaagattaa aagaagcagc
    13261 agaaaaggct aagaaagaat tatcatcaac aatgagttca aacataaact tacctttcat
    13321 aactgctaca gcagaaggac caaaacactt aaatatagat ttatcaagag ctaaatttga
    13381 agaattaact agaggtttag ttgaaaaaac tatggaacca actaagacag ctttacaaga
    13441 tgcaggactt tctacaggtg atatagatga tgtattatta gtaggtggtt ctacaagaat
    13501 accagcagta caagaagctg ttaagaagtt tataggaaaa gaacctcata aaggtataaa
    13561 cccagatgag tgtgttgcag caggtgcttc tatacaagct ggagttttag caggggatgt
    13621 taaagattta ttattactag atgttactcc attatctctt ggtatagaaa ctatgggtaa
    13681 tgtaatgact aagataatag aaagaaatac tacaatacca actaagaagt ctcaaatatt
    13741 ctcaactgct gctgataacc aaacagctgt tgatatacat gttcttcaag gtgaaagaag
    13801 tatggcttat gacaatacaa ctttaggaag attccaatta acagatatac caccagcaca
    13861 aagaggaata cctcaaatag aagttacttt tgatatagat gcaaatggta tagttaatgt
    13921 ttcagctaaa gatttaggta caggaaaaga gcaaaaaata actataacat caaacactaa
    13981 tttatcagaa gcagaaatag agcaaaagat aaaagaagca gaaatgaatg cagaagctga
    14041 caaacaaaag aaagaaaaaa tagaagcatt caatcaagct gaatctacta tatatcaaac
    14101 tgaaaaaact ttaaatgaac ttggagataa aataagttca ggtgaaaaag aggatataga
    14161 aaaagctata gcagacttaa aagctgtaaa agataatcaa gatgctacag cagaagaact
    14221 taagaaagct acagatgaag taatgactaa gttccaaaaa gtatctcaag aaatgtacca
    14281 aaaagcagct caagaacaac aagcggcaca aggtgcagaa caagcacaag acaatggacc
    14341 taaagatgac aatgtagtag atgctgactt taaagaagta gatgaagata aataagctat
    14401 ataatatgta acactaaatg ataattggaa catatatgat ttgtgaaaat catatagatg
    14461 ttaaagatat atggacaata cacatcataa agaatataat atatcataga ttatataact
    14521 taaagtagaa tataagaatt aatgatagct tgtagtttat tattctacaa gctatcgttt
    14581 tgtaaaatga aggtggtgtc aatttttgag tacaaaaagg gattattatg aagtcttagg
    14641 tatcagtaaa gatgcagaag ctcaagagat aaaaaaagct tatagaaaat tagcaatgaa
    14701 gtaccatcca gatagaaatc ctggagataa agaggcggaa gaaaaattta aagagataaa
    14761 tgaagcttat gaagttctat ctgatgatac aaagagaaaa acttatgacc agtttggaca
    14821 tgatggatta aatggtcaag gtggttttgg tggtcaagga ggatttggcg gtcaaggctt
    14881 tggtggtttt gaagatatgt tcggagatat atttggtgac atgtttggag gaagcttcgg
    14941 aggtggaaga gcaagaagaa gagggcctca acgtggtgca gatataagac agagtgttac
    15001 tatatctttt gaagaagctg catttggtaa aaagatgtct ataaaagtaa atagaagtga
    15061 agagtgtgaa gaatgtaatg gaactggagc aaaaccagga acatcaaaga aaacttgttc
    15121 aacttgtaat ggaactggcc aagttagaac tgttcaaaga actccatttg gtaatatagc
    15181 aagttcaaga ccatgtagtg cctgtaatgg aactggagaa gtgattgaat ctccatgtag
    15241 taaatgtcat ggaactggaa atacaagaaa agttaagact atagaagtag atatacctgc
    15301 tggtatagat gatggtcaaa tgataaaact ttctggtcaa ggtgaagtag gagaaaaagg
    15361 tgctccaaga ggagacttat atattgtagt taatgttaag tcacatccac tatttactag
    15421 agatggaaat gatatttatt ttgaaatgcc aattacattt gttcaagcaa ctttaggtga
    15481 tgagatagaa gtacctactt tggatggaaa agttaaatat agtgtgccag aggggacaca
    15541 aactggaact gtatttagac ttaaagagaa aggaatccct agaattagag gtaattcaag
    15601 aggagaccaa tatgttaagg ttgtagttga aattcctaaa aaattaaacg ataagcaaaa
    15661 agaactattg agagaatttg cgaaggagtg tgggtcgaac gtccacgaaa agaagaaaac
    15721 cttcggacaa aagatagaag atatgtttaa gaaaaagtag ttaaagtagc caatatataa
    15781 tcatattttt gaaatcttag ttatttataa gattgtcaaa ggagatatta tgatttttat
    15841 attggctatt tttgtataaa aaataaatgt gcataaaata aaactgaata taaataattt
    15901 tctgaaaaat acttgtccta aaatatataa tgtgctataa tataatcaaa taaaagaaag
    15961 gggtgattcc agtgggaacg gatgtggcac tgccaaatga tgaagaaaac tttattgtaa
    16021 tatacaaaat aaaattagat acttttagtg ctagattaag tactggaaaa actcatgagc
    16081 tgggataatt attgtaatta cctagactca aacttttagt agtaaaatag taatattata
    16141 tagacaaggt atctaatttt taaatctttt gtatgagtta aaatttttat aaagggtata
    16201 tctgattaga atgtaattag ggaaacctag ttgtgaatta cttttagtat atacatgtgt
    16261 aaagaaatat gtatatggta ttggttattg tgctagatgt gtatgtaaag gaatatgtgt
    16321 ctagttgggt atatgtaaag aaatatactt ataatctatg aaaaattttt agtataaatt
    16381 gctaaaacat tgagattgtt ttttatagaa agttagttta taccaactaa aaatgtgctt
    16441 aagatttgtt tgatgtttaa ttataaataa ggttgtagat aaaaaaataa gtaaagacaa
    16501 aggtttaaaa tacttgcttt aaatatagtt tgttttgaac acttgccaaa ttaaaataat
    16561 taataaaata gacatcttct catagtaaaa tatactgtga gaggatgttt ttgctttgtt
    16621 cataaacttt tatgaaaaat ttgcatagtg tcacatttta atatactata tatataataa
    16681 aatatagata aaattaaatg attcaaaaga gaaaggtgaa aagagatgta ttatataggt
    16741 gtagacatag gaggaacagg tatacaagca ggagtagttg ataactatgg gaagataatt
    16801 tttaggtcag agtgtaaaac agtaattgaa aaaggctttg aaggaatact taatgacata
    16861 aaaataatga tttataagtt gttggaagat aataaactta ctatgagtga cataaaatct
    16921 attggatttg gtgttccagg ttttataaat aaagaaggat tagtaacttg tgtaaattta
    16981 aaatggaata aaaaagcttt taataaagag ttaaaaagaa gatttccaga tgctgaaatt
    17041 catggagaaa atgatgcaac agtagcagca cttggagaag caaagtttgg aagtatgaaa
    17101 ggtgctaatg ttggagtatt atatacttta ggaactggtg taggtggagg aatagtaatt
    17161 aatcaaaaag tcttttctgg agcacatgga ttgggttcag aaataggtca tcaaattata
    17221 ggagaaaact attttaattg taattgtgga aataatggtt gtgtagaaac tttttgttca
    17281 gcaactgcaa ttataaagta ttctcaaaaa ctgatagaag aaggagaaaa gagtaggatt
    17341 ttagatttgg cagagggaaa tttagaaaat gtaaatgcaa agatggtgtt tgatgcatat
    17401 agagaaaatg atttagtggc aattaaagta ataaatagat ttaaagatta tttagcaaaa
    17461 acttttgcaa acacaataaa ttctttagac ccagaaatta tatctatagg aggaggcatt
    17521 tctaaatcta gcgatataat acttgatgga atagaagatt tggtaagaaa atttgtatta
    17581 tacaaaacag aagatatagc tacaattaca tgtgcaactt taggttcaga cgcaggaatt
    17641 ataggagcag cttttttata atgtaaatga actgcttatt ggaggcgtga tgatatatgg
    17701 gtaaaacaaa tgctagaaga acgctttttt tgatagcaat aggttcagga actatgctga
    17761 atcctcttaa ttcttctatg atttcacttg ctttacatag tatacaaaat gattttcata
    17821 ttagttttac aactgtatct tggattgttt cagcatttta cctagctagt gctattgcac
    17881 aaccagtttc aggtaagata ggagatttaa taggtagaaa ggtcttattt ttgagtggtt
    17941 tgatgcttgt aattttatca gcatccatag taccacttgt tcaatcattc tttatattga
    18001 tttttataag agtaattcaa gcaattggaa caagtaccct atatccatct ggagttgctc
    18061 ttatacaaaa taatataaaa gaaagacaat cttctgcatt agcagttcta accatttttg
    18121 cttcaactac agcaggatta ggtccgacac ttggaggatt attgttggac ttaggaggat
    18181 ggcatgctat atttcttgta aatatacctg ttgttttggt ttctatatgc ttagggtatt
    18241 ttttattccc aaaagaagta aaagaaaaga aatctataaa agaaacttta aaaaatgttt
    18301 tgtcaagatt agatattatt ggcatacttc tattttcaat tgcaatgatt tttatattac
    18361 tatttttgct atctatgaag gaatctttta acttagaaca acttgtattt ggtataatac
    18421 tgatgtgtct ttttatttgg catgaattga gaacaaaatt gccatttata gatattaagc
    18481 tttttgtaag taatcctaaa ttgtcaaaag tttacttgca atttattata ttaaatttct
    18541 ttaattatat tttgtttttt ggtcttccta gttattttca agatgcctta cattatagtg
    18601 caaagtcgac tggattattt atgctattta tgtctggtat aggtatattt atatctccat
    18661 taactggaaa atggatagat aaatctggaa ctagatttcc tcttgttaca tcatcaatct
    18721 ttatgtttat tagtgcagta cttctttcag tagtttttat ccatatacct gtaataggaa
    18781 agggtattat attatcatta gcaggtatta gttatggagt tggtaatgta gccctgcaat
    18841 cctctatgtt tgaagaaagt cctcgtgaca gtatagggac agcttctggt ctgtttcaaa
    18901 ctagtcgtta tttaggttct attttagcaa ctgttttact tggaatggta tttgaaggaa
    18961 atataacatc agaacaattt cagatattag gttatgttat ggtggtctta ggtacaataa
    19021 gttttttatt aaattttata ttaaagaaag aattaagaaa agtagaatag tggatttatg
    19081 gatttaataa gtctaataac tgataagttt aaaaatattg tttgtaaaac ataactggtt
    19141 tgatatttat taattctaag ttttgaagca tagagtactc gataagtata caatattttg
    19201 aattaaaatt aagcagaaat ttgaactagt ctttcaaatc tctgcttaat ttagtagtta
    19261 aattttttta tagagaaaat aagatttgac acttagataa aaaatcattg cattttcaaa
    19321 attctttaaa tcaaacccaa gtatctcatt aatcttttcc aatctatata ctagcgtgtt
    19381 tctatgtaaa aacatactag tagatgtctt agaaatattt aaatcattat ttataaattt
    19441 tattcctgta tatagaagtt cttcgtcaat agatttaatc ttattaaaat ctattaattt
    19501 attgagtata ttatcctcat taattaaatc taaagtttta tatctaataa ggtcaaacaa
    19561 atttaaaaac ttattttcag cattgtcttt tataatatga ggtagtaaat cagaacataa
    19621 ctgtaatcta aaataaaaat cagctttact atctaattca ccaagataaa aaatataagt
    19681 actttgataa gtttcagttt caattatatt ttgtgtagtt acattaatat ctaaattata
    19741 tttagaattt actataaaaa aaccattgtg ttgtattata tttatatctt caaataaatt
    19801 ataaaaaata ttttttaggt attcaaagtc tatatgagat tggtaaatta aataaaagtt
    19861 gccttttaaa ttatcaagat tatttttatc tagaaaatca ataacataaa tagcattatt
    19921 gaaagtaact aaatggctac tagcatctaa cttttggttt tcatagggat agatatttat
    19981 ttttttatta agctgtcttt ctaaaaaatc ttttaactct tccataaagt ctccttaaaa
    20041 ataagattat attcttatct tatagctaaa gtagtttctt tgtcaaatat gtgtactcta
    20101 ctattgtcaa ctgaaagtgt taagtcatca ccaacattaa ttctgttttt actgtcaaat
    20161 ctaattgtta tcgtattttc gcctagtttt aagtgagcat aagtttctgc tcccataagt
    20221 tcttttattt caattcttga tttaaaacaa gtatctggat tagatttaat aaaagtatct
    20281 tctacatgaa tatcttctgg tctgatacct ataacaactt cattattaat ataattgtct
    20341 tttattaaat catagtgttt ttctttattc aatttaagct taatatgttc attttgtgca
    20401 taaattttat cattttcttc tattaatatt acatcaataa aattcatctg tggtgctcca
    20461 ataaatcctg caacaaatat attagctgga taatcgtata catcttgtgg agttgcaatc
    20521 tgctgaacta ctccatcctt cattactacg attctatcag ccatagtcat agcttcaact
    20581 tggtcgtgtg ttacatagat aaatgtagtt ccaagctgtt ggtgtagctt agttatctct
    20641 gttctcatag cagttctaag ttttgcatct aagttggata gaggttcatc cattaagaat
    20701 accttaggat ttctaactat tgcacgtcct aaggcaaccc tttgtctttg tcctccagat
    20761 aatgttttag gttttttatt taaaagaggt agtaagtcta atattttagc agcttcttta
    20821 acttttttgt ctatttcatc tttaggcaat tttctaagtt taagtgcaaa tgccatgttt
    20881 tcgtaaacag ataagtgggg atataaagca tagttttgaa aaaccatagc tatatctcta
    20941 tcttttggtt ctatatcatt gacaagttta tctccaatgt atagttctcc ttcagagatt
    21001 tcttcaagac cagcaatcat tctaagtgta gtcgatttac cacaaccaga tggtcctact
    21061 aaaacgataa attctttatc tttaatgtct atatttatat tttttactgc gttaaatcca
    21121 tttgagtaaa gttttgatat attttttaaa attacttctg acataatatt ctccttgata
    21181 tttaaatttt aatgatatag tatcaaattt ttttattata ttaaatgtgt aaaatgacta
    21241 aatgt
//
LOCUS       DAMJWO010000075        21041 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.076, whole genome shotgun sequence.
ACCESSION   DAMJWO010000075 DAMJWO010000000
VERSION     DAMJWO010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21041
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.076"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            245..1306
                     /locus_tag="PC366_002831"
     CDS             245..1306
                     /locus_tag="PC366_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HDF2578328.1"
                     /translation="MRDFLKNYKSSIILLACTIIGVIVGLVLGPKASILKPFGDLFIN
                     ALLMIVVPLVFLSVSSGVASIKNMERFGKIMKSTAIVFMGTTLVIAFLGITSALLFNP
                     SKGLDVSSVKSLMVAQDAETLESKGTLLDQVVSSITVKNFGDLFSSSNLLQLVIFAVL
                     VGTAIAMMGDRGNTIRKFLSEGTEAILKVVSIVMLYAPIGLGCYTATIIGELGSKIIQ
                     GYVRVFVIYSLTAAMYFLLFYSLYAFLSAGKQGFRQFWRNAIKPIATALATSSSSACI
                     PSNLEASKNIGVPDDISETVIPLGINIHKDGSVLAVIIKVAFLSGILGSGMANPATIG
                     QLFITVFVVGVFMAPVAGG"
     gene            1319..1516
                     /locus_tag="PC366_002832"
     CDS             1319..1516
                     /locus_tag="PC366_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HDF2578329.1"
                     /translation="MLVVSIFGFPVEAIPLLTVITTITDIPNTILNTTGNTVSSMLVS
                     RLVEGKDWLIDKTAITTKKIS"
     gene            complement(1680..2408)
                     /locus_tag="PC366_002833"
     CDS             complement(1680..2408)
                     /locus_tag="PC366_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF2578330.1"
                     /translation="MKTNYRLHMQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEM
                     LECLGVVDKTYPKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLF
                     GEVFACTRLHKSNVTVTTTSSCEVLFIKFKSVTGICSSACVFHNRLVENMLQLIAEKN
                     ILLHNKIELLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRE
                     LGKMRDEGLLSFNKNKFEIFYFQK"
     gene            2549..3274
                     /locus_tag="PC366_002834"
     CDS             2549..3274
                     /locus_tag="PC366_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2578331.1"
                     /translation="MMRKIIKIDEGKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKAQKKTLACGCPGSQSKSINRE
                     VSNSTSISNDIVEIKGSQLNQWPVQIKLVPTNASYLKNASLLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEVDYAEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            3334..4926
                     /gene="hcp"
                     /locus_tag="PC366_002835"
                     /gene_synonym="priS"
     CDS             3334..4926
                     /gene="hcp"
                     /locus_tag="PC366_002835"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HDF2578332.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGGTANLQDELTGVLIGL
                     SRATIGNKNRPTSETDKIMIEGLFTTITNVSFDDEAIKRQIEKTEVEKSKLVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYREDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGAIRHFLLVGGCDGAKLG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDIGGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            5290..6195
                     /locus_tag="PC366_002836"
     CDS             5290..6195
                     /locus_tag="PC366_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF2578333.1"
                     /translation="MKSSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKYIFNKSYAEILRPKYENKNLKEVLLSIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFKLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKDVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            6319..7272
                     /gene="msrA"
                     /locus_tag="PC366_002837"
     CDS             6319..7272
                     /gene="msrA"
                     /locus_tag="PC366_002837"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDF2578334.1"
                     /translation="MIKLATFAGGCFWCMVKPFDKYDGVIKVVSGYTGGHVENPTYQE
                     VCSGTTGHLEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESREHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTPIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRIEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPRENMEVLGYGEYLKLFE"
     gene            7425..8555
                     /locus_tag="PC366_002838"
     CDS             7425..8555
                     /locus_tag="PC366_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2578335.1"
                     /translation="MNLKDFNGKRLKSARIFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEYFYKNENINIVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPNRKVMSDINISDIESLAYKTREFWDLNSTPIVNMVSLLES
                     KGIIISGMNVDRKGATIFTQKQRISKESKYLISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPSKQFSEDEYACAFLLPKESFLKDLTHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LEKINYKKYNYLMNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLEEFGINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDGKK"
     gene            complement(8672..9640)
                     /locus_tag="PC366_002839"
     CDS             complement(8672..9640)
                     /locus_tag="PC366_002839"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HDF2578336.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTKL
                     RRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPNTYSNLDLP
                     SIVEKNKKTGISIINGKDCTEFGIGTALVEIVKAILHNEKKVLPVSTLLEGQYNERNV
                     FAGVPCVIGKDGIEEIIEINMTEYEQNEFNKSCSVLRECIALSKTL"
     gene            9975..10163
                     /locus_tag="PC366_002840"
     CDS             9975..10163
                     /locus_tag="PC366_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578337.1"
                     /translation="MNYHTKEELMEVLRVASSRIINCEKVQKKFSEETSHHTRFKNII
                     EAMYISKSLIMDEISKRD"
     gene            10423..11622
                     /locus_tag="PC366_002841"
     CDS             10423..11622
                     /locus_tag="PC366_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA editing protein AlaX-L"
                     /protein_id="HDF2578338.1"
                     /translation="MEKLYYTNQYIRDFTAEIIEIKEVENKYHVLLDKTAFFPGGGGQ
                     FGDLGKIENDDVINVYEDGKNIYHVLDKKPIKIHKVKCSIDWDRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGNEYSTVDIEGNLEENKIREIELFANEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVIKIGDLDTNACCGVHPKSTGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDEVLKRDIYLTKICRYLSCSEEDAINGIVNLNSKVEEALIKKRRLE
                     EVVSTYQVKEMIEKANKVGNISVIKKIYDDEDLKYVNKIANKIAEYENSIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAISLIDGKGGGSKVLAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            11674..12177
                     /locus_tag="PC366_002842"
     CDS             11674..12177
                     /locus_tag="PC366_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2578339.1"
                     /translation="MEQQKDYIELYENEELIEIREARMDDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENINAKATYESLNMYECDYNMY
                     EYEVIHS"
     gene            12284..12601
                     /locus_tag="PC366_002843"
     CDS             12284..12601
                     /locus_tag="PC366_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578340.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSYYPNNNLIGKFIASLFFIFGVAGVMLKEKNFLYARLLLTVVIVFSTLRLF
                     VIQ"
     gene            12759..13718
                     /locus_tag="PC366_002844"
     CDS             12759..13718
                     /locus_tag="PC366_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF2578341.1"
                     /translation="MIESKKSEKLLLSIIYIIFLVYILMIIRIILFRDVPIYAIFKGT
                     FRNVNLIPFYTIYQFIVDSNLDFMKATVNIIENIGIFIPMGIFLPIVCKNLNKKTIII
                     VIILVSLAFELTQYIFALGSSDIDDVILNSLGGIIGINIYINMNKLFPNDIKRFKAII
                     ATSLVLGVLGLGVISKNYHNLLTFKFRPDRKISKILIEENREIIKDINKDTVDIVGTF
                     ESFKKGIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYE
                     EFDVKNLDLLRRYDTINVWIDKENQPKDKHGIMASKLLIGLYE"
     gene            13833..14618
                     /locus_tag="PC366_002845"
     CDS             13833..14618
                     /locus_tag="PC366_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HDF2578342.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDRKFN
                     IKGRVCLKNAIYFGVMSVLIIRFIHPFIKYFVSIIPYRILISMAIITTLWTILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDGLEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            14910..16229
                     /locus_tag="PC366_002846"
     CDS             14910..16229
                     /locus_tag="PC366_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2578343.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMSIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(16304..16732)
                     /locus_tag="PC366_002847"
     CDS             complement(16304..16732)
                     /locus_tag="PC366_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578344.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RKKDDKKKGNKKKNTNTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAILII
                     TKLTDSTNKGNYSRNTVSDTHKNDIRNIVFNESNNFLICG"
     gene            complement(16823..18199)
                     /gene="hydG"
                     /locus_tag="PC366_002848"
     CDS             complement(16823..18199)
                     /gene="hydG"
                     /locus_tag="PC366_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HDF2578345.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIKEEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLIAEEIGKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(18200..19285)
                     /gene="hydE"
                     /locus_tag="PC366_002849"
     CDS             complement(18200..19285)
                     /gene="hydE"
                     /locus_tag="PC366_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HDF2578346.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSPDEILE
                     CCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNKDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(19321..20529)
                     /gene="hydF"
                     /locus_tag="PC366_002850"
     CDS             complement(19321..20529)
                     /gene="hydF"
                     /locus_tag="PC366_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HDF2578347.1"
                     /translation="MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
                     IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDNGAISIVTKEDSLKETLSNLGKKPKLVITDSQVFPQVNKDTPKDIPLTSFSILFAR
                     QKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGILIAYVKGI
                     LERSLELFNY"
     gene            complement(20544..20795)
                     /locus_tag="PC366_002851"
     CDS             complement(20544..20795)
                     /locus_tag="PC366_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-only hydrogenase system regulator"
                     /protein_id="HDF2578348.1"
                     /translation="MKKVAVISAILEEPKECQFKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDTINSLTGKLGNIPHVSVKTSISKKEV"
BASE COUNT         7930 a         2472 c         3402 g         7237 t
ORIGIN      
        1 taaaattaat ctagaaaaaa agttttaaaa gcagaatttt attaatattt atatatagat
       61 atgaactatt aataaaatat taaagataca aaaaaactat agaaattgac atatattcca
      121 gtatttgcta aagtagctgt tggggaaaat tacaaaaatt attaatgcgc attagataat
      181 ttactttaat ttttttagga tttagggtaa tttataatat aaaacattag aaaggaaaat
      241 ataaatgagg gactttttaa aaaattataa gtcatcaatt atacttttag catgtactat
      301 aataggggtg atagtaggat tagtacttgg tccaaaagct tcaatactaa aaccatttgg
      361 agatttattc ataaatgctc tattaatgat agtagtacca ttagtttttc ttagtgtttc
      421 ttcaggtgtt gctagtataa aaaatatgga acgttttgga aaaataatga agagtacagc
      481 tatagtattt atgggaacaa cacttgtaat tgcattttta ggtattacat ctgcattatt
      541 atttaatccg tctaaaggat tagatgtatc aagtgtaaaa agtttaatgg tggctcaaga
      601 tgcagaaact ttagaatcaa aaggaacgtt attagaccaa gtagtatcaa gtattacagt
      661 taaaaatttt ggagatttat tttccagtag caatttacta caattagtta tatttgcagt
      721 tttagttgga acagcaatag ctatgatggg agatagggga aatacaataa gaaagttttt
      781 atcagaagga acggaagcaa tattaaaagt agtaagtata gtcatgcttt atgctcctat
      841 agggctaggc tgttatacag ctacaataat tggggaactt ggaagcaaaa taattcaagg
      901 atatgtaagg gtgtttgtaa tttattcact aacagcagcc atgtatttct tattatttta
      961 cagtctgtat gcttttttat ctgcaggaaa acaagggttt agacaattct ggagaaatgc
     1021 tataaaacca atagcaacgg cactagctac ttcttcaagt tcagcatgta taccatcaaa
     1081 tttagaagct agtaaaaata taggagttcc tgatgatata tcagaaacag ttatacctct
     1141 tggaataaat atacataaag atgggtcagt tttagcagta ataataaaag tggcattttt
     1201 atcaggtatt ttaggcagtg gaatggcaaa tccagcaacg ataggtcaat tatttataac
     1261 tgtatttgtt gttggagtat ttatggctcc tgtagcaggt ggctgactta ttggtgagat
     1321 gctcgtggtt agcatcttcg gttttccagt ggaggcaatt ccattgttaa cagttataac
     1381 tactataact gatattccta atactatatt aaatacaact ggaaatacag tatcatcaat
     1441 gttagtttca agattagtag aaggaaaaga ttggcttata gataaaacag caattactac
     1501 aaagaaaata agctaattgt acacttaatt aataaagtta ataggtatct taattttaat
     1561 aaattagata tctattaact ttttaagtaa aaatataaat ttaagattca aatatgatat
     1621 ttataatttg aattaactaa tatagtatat attgaaataa atatgtttaa atatctagtt
     1681 tatttttgaa agtaaaagat ttcaaattta tttttattaa aagataacaa gccttcatct
     1741 cgcatcttgc caagctctct tgacatagaa cttctgtcaa cacataaaaa atcagccatt
     1801 tcatttcttg aaaagggaat tgtaaactgg tggctacctg tttgttctat ctgttttgaa
     1861 aaatacataa gcaatttctc gcgagttgtt ttacgagaaa gtaattctat tttattgtga
     1921 agtaaaatgt ttttttcagc tattaattgt agcatatttt caacaagcct attatgaaat
     1981 acacatgcag atgaacaaat accagttaca cttttaaact ttataaataa aacttcgcaa
     2041 gaagatgttg tggttactgt aacattactt ttatgtagtc tagtacatgc gaatacctct
     2101 ccaaataaat ctccaggcaa gagttcagct acaatattcc tattcccttc gatatcttcc
     2161 tttattatat gagcacttcc tttaagcata attccaatag aagtaacttc acttccaaca
     2221 gagaatatta tactatcttt tgggtaagtc ttatctacaa cacctaaaca ttccaacatt
     2281 tcttcaagct catcactttt aattccttca aatagaggaa tttttttaag taggtctata
     2341 tgcttttcta aaaatttttt caaataatca cttccttgtt gcatatgcaa ccgataattt
     2401 gttttcattg tactatacta agtttataaa agcaagggga tataaaaatc ctactacaag
     2461 aaatttgaaa taaagaaata taggtattaa aaataaatat ataagaaatc aatactttaa
     2521 attaaaaaaa ttttatgagg tgatataaat gatgagaaaa ataattaaaa ttgatgaggg
     2581 aaagtgtaat ggttgtggac tatgtgttga agcttgtcat gaagaagcta taggaatggt
     2641 aaatggaaaa gcaaaacttt taagagatga ctattgtgat gggctgggag attgtctgcc
     2701 aacttgtcca acaaatgcga tttcatttga gtatagagaa gcagcagaat atgatgaagc
     2761 tgcagtaaaa gcaaatatgg aagcaaagaa agcacaaaag aaaactttag catgtggatg
     2821 tccaggttct cagtctaagt caataaatag agaggtttca aatagtacat ctataagcaa
     2881 tgatatagta gagataaaag gttctcaact taatcaatgg ccagtacaaa taaaattagt
     2941 accaactaat gcatcatatt taaagaatgc aagtctttta atagcagcag actgtacagc
     3001 gtatgcatat ggaaattttc ataataaatt tatgaaaaat aaggttacat taatcggatg
     3061 ccctaaactt gatgaagttg actatgctga aaaactgaca gagattttaa aagaaaatga
     3121 tattaaaaat atagtagtaa cacgtatgga agttccttgc tgtggtggta tagtaaatgc
     3181 tgttaagaca gctctacaaa atagtggaaa aatgatacca tggcaaatag ttactatatc
     3241 tgtagatgga aaaattgtag atggagaaat ttaattaagt gaatcataga aaaatataat
     3301 aaattttaat aaataaaaag ggaggaataa aaaatggaaa aaatgttttg ttttcaatgt
     3361 gaacaaacag caggaggtaa aggttgtact ataaatggtg tttgtggtaa aaaggggggt
     3421 acagctaact tgcaagacga gcttacagga gtgttgattg gtctttcaag agcaactatt
     3481 ggaaataaga atagaccaac aagtgaaaca gataaaatta tgatagaggg gctattcact
     3541 actataacga atgtaagttt tgatgatgaa gctataaaaa gacaaattga aaaaactgag
     3601 gtagaaaaaa gtaaacttgt acctagatgt tcagattgtt caacaacttg taatagaaat
     3661 gataactatg atatgaagga tttatggaat gataatgagg atatacgttc attaaaatca
     3721 ttaatcttat ttggattaag aggcatggct gcctatgcat atcatgcaat ggtacttggt
     3781 tatacagaca aagacgtaaa tgaatttttc tatgaaggat taatagcagt tggaggagac
     3841 ttgtctattg acgaactttt aggtctagtt atgaaaactg gagaaataaa cttaaaatgt
     3901 atggaattgc ttgatagagc aaatactgaa acttatggaa caccagaacc gactcaggta
     3961 tctatgaaaa tcgagaaagg gccatttatt gtagttacag gacatgacct ttatgattta
     4021 cacaaattat tagaacaaac gaaagataag ggtataaata tatatactca tggtgagtta
     4081 ttaccagcac atgcatatcc aaaactaaaa gaatataaac atctaaaagg taattttggt
     4141 acagcatggc aaaaccaaca aaaagaattt gataatattc ctgctccaat attatttaca
     4201 acaaactgtt taatgcctgt taaagatagt tatagagata gagtatttac tacagaagta
     4261 gttgcttatc caggtatggt tcatattgat gaagataaag atttttctag tgtaatagaa
     4321 aaagctcttg aacttggagg atatagagaa gatgttcata tgactggtat taatggagga
     4381 gatacattaa ctactggttt tgcaagaggt acagtttcat ctgtacaaga taaagtagta
     4441 gatgctgtaa agagtggagc tataagacac tttttattgg ttggaggttg tgatggtgca
     4501 aaacttggaa gaaattatta cactgaattt gtaaaacaag ctcctaaaga tactgttata
     4561 ttgacacttg catgtggaaa atatagattt aatgatttag accttgggga tataggtggc
     4621 ttacctcgtt taatggatat gggacaatgt aatgatgctt atagtgcaat taaagtggca
     4681 gtttcattgg caaatgcttt tgaatgtgga gtaaatgatt tgcctcttag catggtactg
     4741 tcatggtatg agcagaaagc tgtttgtata cttcttacac tacttcattt aggtatcaaa
     4801 aatatctata tagggccttc tttgccagca ttcttatcta agaatgtatt agatatattg
     4861 gttgataaat ttgcattgac acctatatct actcctgaag aagatatgaa gaagatttta
     4921 ggataaataa atatatctat acttaaagat atttatagtt aaaatatttt taagtatgtc
     4981 acaattaaga taaggggtta aacttaaaat ttgattaaaa aatcaatttt gagacgaccc
     5041 tttatttatt ttttgtaata attgaaaaat aaacctgctt tcagtatatt cttttaagaa
     5101 tttttgtatt aaatttataa tacttagata tataatatct tatatatttt attttaagta
     5161 ctaaaggttt gaatgtaact taaatattaa aagaggaaca ttgtaatatg taacttgcat
     5221 aaaatatata tactatagtg aaattatttt gattaaaata taaggtgttt tatgtggggg
     5281 tatatgtata tgaaaagttc taattttaat atattggcat ttgatggtgg tggattaaaa
     5341 ggggcattga gtatatccat acttgagagg atagtaaaag agtatccaaa tctattaaac
     5401 aatataaata tgtttggagg gacatctaca gggagtctaa ttgcactagg acttgcgtat
     5461 ggtgtaagcc ctaaagagat aaaagaactt tactcaattg aaaattctaa gtatattttt
     5521 aataaaagtt atgcagaaat actcagacca aagtatgaaa acaaaaactt aaaagaagtt
     5581 ttattaagta tatttccaga ggaactagaa ttaaaagatt taaataaatt agtaatgata
     5641 ccaagttttt atataggaaa tgaggaaaat gcatggaaac cagtgtttta taacaatatg
     5701 ccaaattctt ttacaaagac tagcaaagtt gtagatgtag caatggcaag tagtgctgct
     5761 ccagtatttt ttccaacata taatcgtcat gttgatggag gaataatagc aactgaccca
     5821 agtttagcgt gtataattca tgccattgac agtggattta aacttaagaa tacaagactt
     5881 ttttcaatag ggactggata tgtatataat agtataaagg cagatactac tgaatgggga
     5941 gctattgact ggataattaa taaagaaccc gatttaccaa ttatatctat taccttagaa
     6001 ggaaattctc aaatgagtca gttattttct caaaaacttc ttggagataa ttactataga
     6061 ttaaatccta agatggaaaa agatgtagct atggatgatt gtgatgcatt agaatatcta
     6121 atgtctttag gagaaaattg tgatataaaa gatgcttttg gatggataaa gaaaaagagc
     6181 ttttatagaa attagattca atttgcaatt gtatttttgc acatgatttc attgagtagg
     6241 taaaaataat aaaatgcaga ttattaagtt acttcttagg gaataaataa agtataattt
     6301 atttaaggag tgatgaaaat gataaaactt gctacttttg caggtggatg tttttggtgt
     6361 atggtaaaac ctttcgataa gtatgatgga gttattaaag tagtttctgg atatacaggt
     6421 ggtcatgttg aaaaccctac atatcaagag gtatgttcag gaactactgg tcatttagaa
     6481 gcaattcaaa taacatatga tgatgatata ataagttatg atgaacttct aaatatcttc
     6541 tggaaacaga ttaatcctac agatgatggt ggacaatttg gtgatagggg aactcaatat
     6601 aagactgcta tattttatca tgatgaagaa caaaaaaata tagctttaga gtcaagagaa
     6661 catctggaaa atagtaaaat atttgatagt aaaatagtga ctgatataat tccagcaact
     6721 aaattctacg aagcagaaga aaatcatcag gattattata aaaaaagacc attaaactac
     6781 aatatgtatt ataaagggtc tggaagatat aattttgtaa aaagtcattg ggatggaaac
     6841 aatataaata gggaagagtt aaaaaagact ttaactccta tacaatttga agtcactcaa
     6901 aatgatatga cagaagtacc ttttgaaaat gaatattatg ataataacaa agagggaatt
     6961 tatgttgata ttgtaagtgg agaagtgtta ttttcttcaa aagataaatt tgattctgga
     7021 tgtgggtggc caagtttttc aaagccagtt atagataaat ctatcattga gagaagtgat
     7081 ttctcacaag gtatgtacag aattgaagta agaagtgcta aaggaaattc tcatttaggt
     7141 catgtatttg atgatggtcc aaaagaactt ggaggtttaa gatattgtat aaattctgct
     7201 tctcttaaat ttataccaag agaaaatatg gaagttttag gatatggaga atatttaaaa
     7261 ctttttgagt aattaggaat atttattata aacttatcta aaaggtgaaa atataaaaaa
     7321 atattttcac cttttgtttt tttgtcaata atatgataaa ttattaattg taatcttatt
     7381 tataccaata gattaagaat ttaattttga aagagagaaa acaaatgaat ttaaaagact
     7441 ttaatggaaa gagattaaaa tcagctagaa tttttagagc aaagacgata gaacagttgt
     7501 ctaaagaaac taaaataaat aaaaaagatt taaaagcttt tgaggaaaat aagtatgtac
     7561 caaatataga aaatacatta aaattatcta atatattaaa ttttccaaaa gagtattttt
     7621 ataaaaatga aaatataaat atcgttgtag aggatagcca ttttaaccct caatctaaac
     7681 tacctagagt agaagagatt tcttatagag aaaaaataat tataatacat aaaatatatt
     7741 catttatgga gaattatatt aagtttccaa aagaaaactt gccaaataga aaagtaatgt
     7801 cagatattaa tataagtgat atagaatctc ttgcatataa gactagagag ttttgggatt
     7861 taaatagtac tccaatagta aatatggtaa gtttgttaga atctaaaggg attataatat
     7921 caggtatgaa tgtagataga aaaggggcaa ctatctttac tcaaaaacag agaattagta
     7981 aagaatctaa atatctaata tctctgggta atgacaaaaa gtcagcatca attagaaatt
     8041 atactttggc atgtgagctt ggatatataa tatcaagtga attaagaata ccaagtaagc
     8101 aattttcaga agatgagtat gcctgtgcat ttttattgcc aaaagagagt tttttaaaag
     8161 atttgactca tccagaagat ttagattatt atgtagaact aaagaaaaaa tggattgtac
     8221 ctatatctgc tatgattttt agagcatata atctagaaaa gataaattac aaaaaataca
     8281 attatcttat gaatgaaatg gataaaaaag gctggttgat agaagaacca ctagacaaaa
     8341 tgaaaggttc aagcccaacg tatttaaaaa gagcagttga attattgata gaaaataaaa
     8401 taatgagtgt aaatagtata gtatcaagtt tagaggaatt tggaataaat ctttatccag
     8461 aagacttaga attattgatg ggattgaaaa aaggattgtt atctcaagag gtaaataaaa
     8521 aaagtaaagt tataaaattt gatggtaaaa aataggttta tattttagta ttaaaattaa
     8581 aagcaggtat aaatgattta aacattaact tagttaaaag tcttttcaat aagtcattta
     8641 cctgctttta gtgtaagaaa gaatattgaa tctaaagtgt ttttgaaagt gcaatacatt
     8701 ctcttaaaac agagcaagat ttattaaatt cgttttgctc atattcagtc atattgattt
     8761 caataatttc ttcaatacca tcttttccta taacacatgg aacacctgca aatacatttc
     8821 tttcgttata ttgaccttct agtaatgtag aaactggaag aacttttttc tcattgtgta
     8881 gtatagcttt tacaatttct actaaagcag tacctatacc aaattctgta caatctttac
     8941 catttattat acttatccct gtttttttat ttttttcaac tattgatggt aagtctaaat
     9001 tgctataagt atttgggttg tcttttatca tgtccaagat tggtttacca ccaattgaaa
     9061 catgagacca aggaaccatt tgagaatctc catgttcacc catagaataa gcttgaattg
     9121 attgttgagc gattccagtt tcttcagata aaatccttct aagttttgtt gaatctaaag
     9181 ctgttccagt tccaatgact ttatttttag gaaagccaga tttttcccaa atataatttg
     9241 taactacatc aacaggatta gatatgacta caaatatacc atcaaagcca gaatcaacta
     9301 tgggttttac tatagatttt atcattccaa tagttggtct tagtaaatct aatctagttg
     9361 tgttttgtct acgtaaaggc ccttctgaag agtctgcaac acttatcact actatgtcag
     9421 aatctttaca gtcagaaaaa gttccttttt ctatatgtac tttatgtggt agatatgaaa
     9481 ctgcatcagc taaatctaaa gcttgagctt ttgatttaga ttcatctata tcaatcataa
     9541 agagttcatc acaaactcct tgagttatta aactaaatcc acaatgagaa ccaacatgcc
     9601 ctgaacctac aatagatatt tttcttggct ttattgccat tttaaatcac tccccctaaa
     9661 ataacgatac attgaaaatt atagatgtta tcaaaagctg tttttggata ttttaatatt
     9721 ttattatttc agaaaattta tttaatatga ttttatacta aaatttttaa aaaagcaatg
     9781 ttaatatact ctctattaat gaatgttaaa gtattatatg tatattaata attattaaaa
     9841 tatgtaatgt cactgatagt tagaatattt aagtgttaaa agatatatat aaataataat
     9901 gatatcagtt gataatgata ttaaattgag gtatactgtt tctctaaatt aaaaaacaaa
     9961 ggagtaaatg tgttatgaat tatcatacaa aagaagagtt gatggaagta ctgagagtag
    10021 catcttcaag gattattaat tgtgaaaaag tacagaagaa attttctgag gagacatctc
    10081 atcatacacg ttttaagaat attatagaag caatgtatat ttcaaaatca ttaataatgg
    10141 atgaaattag taaaagagat tgaagcttat tttgcaattt aatatgtttt aatatacatt
    10201 ttattatata agaaaataag taagcatact tgttataaaa tattgaaata atataaaatt
    10261 ataaatttgt taacactaat atctatatgt taaaatatag tagaagatgt tagtaaataa
    10321 taggatgagt tctattttaa tacaattaaa ttaagcttag cttgaaattt gtatttaaaa
    10381 agtaaagtag tctataatta agaaaatgga gatagaatta taatggaaaa gttatattat
    10441 acaaatcagt atataagaga ttttacagca gaaataattg aaataaaaga agtagaaaat
    10501 aagtatcatg ttttattaga taagacagct ttttttcctg gtggaggagg tcagtttgga
    10561 gacctgggaa aaatagagaa tgatgatgta ataaatgtgt atgaagatgg aaaaaatata
    10621 taccatgtat tagataaaaa acctataaag atacataagg taaagtgtag tattgattgg
    10681 gatagaagag aagatggaat gcatcaacat tttggacaac atgtattatc tggatgtttt
    10741 tttaaaactt ttaatgcaaa tacgacaggt tttcatttag gaaatgagta tagtacagta
    10801 gatatagaag gtaatttaga agagaacaaa attagagaga tagagttgtt tgccaatgaa
    10861 attattcgcc aaaatataca agtagagaca ttacttccaa cgaaaaaaga actaaaaaag
    10921 atttggttaa gacgtgattt gccaaatact gatgaagaga taagagtaat aaaaataggt
    10981 gatttagata cgaatgcatg ttgtggagtg catccaaaat caactggtga attgagaatg
    11041 ataaaaataa agaaatggga aaaacataag tcaagtacaa gaatagagtt tctagcaggt
    11101 aaaagggcag tggatgaagt attgaagagg gatatatatt tgactaaaat atgtagatat
    11161 ttaagctgta gtgaggaaga tgctataaat ggtattgtaa atctaaatag taaagtggaa
    11221 gaggctttaa ttaaaaaaag aaggcttgaa gaagtagtat ctacatatca ggtcaaagaa
    11281 atgattgaaa aagcaaataa ggttggcaat atttcggtca ttaaaaaaat ttatgatgat
    11341 gaagatttga aatatgtaaa taagatagca aataaaattg cagaatatga aaatagtatt
    11401 gcattattag ctgttaaatt taatgataaa ataaatttag tttttgcatg ttctaaaaat
    11461 ttaaaagata ttaatatggg agttttatta aaggatgcaa taagtcttat agatggcaag
    11521 ggtggtggaa gtaaagtatt agctcaagga ggaggtaaga ataatggaaa tttagaggct
    11581 acacttgatt atgcatttat gaagatagaa aaaactctat aaatatatta tataaaaaac
    11641 cttagtagat aaaatagata tggaggaata agtatggagc aacaaaagga ctacatagag
    11701 ttatatgaaa atgaagaact aatagagata agagaagcac gtatggatga tttggataca
    11761 atagcaaaat ttaattataa tttggctaaa gaaactgaag gaaaagaact tgatatggat
    11821 gttttaacta aaggtgtaaa agcattgtta ttagatgaga gaaaaggaaa atatcatgta
    11881 tatacagtat ttgataaagt tgttgcacag attatgtata catatgagtg gagtgattgg
    11941 agaaatggaa atttcctttg gattcagagt gtatatgtag ataaggaata tagaagaaaa
    12001 ggtatcttta attatttatt taattatata aaaaatatat gtgataaaga tgaaaatata
    12061 gttggaatga gattatatgt agaaaaagaa aacataaatg caaaagcaac atatgagtct
    12121 ttaaatatgt atgagtgtga ttataatatg tatgaatacg aagtaataca ttcgtaatat
    12181 aaatttgtaa tactgttata ctgatgttat aaagtattga ttatattgac gattatatga
    12241 aataaactgg atattataat tagaattttt agggggtata aaaatgggcg ttttaaaagg
    12301 aatgttttat gtatttttat ttttagattt agtgtcaata ttctgtttct ttttcaataa
    12361 aggaaaaata gcatctaata aaattgtgtt taatgcaata ggagtactta catttgtact
    12421 ttgttttatg ctttttagtt attatcctaa taataatctt attggaaaat ttattgcttc
    12481 tctatttttt atatttggag ttgcaggagt tatgttgaaa gaaaaaaatt ttttatatgc
    12541 tagacttctt ttaactgtag ttatagtttt ttctacatta agattgttcg ttattcaata
    12601 aaatgtattt gtatgaaaat ttattaaagt ctacacattt aagtgtaggc ttttttgatt
    12661 ttttgtttga aaattaagga aattttaagg aaattttaaa atcgtcttaa atatttattg
    12721 atatacttaa aatattaata gcgaaaggag acttatcagt gatagaaagt aaaaagtcag
    12781 aaaaattgtt actgtcaatt atatacataa tatttttggt atatatttta atgattataa
    12841 gaataatttt atttagagat gtaccaattt acgctatttt caagggaacg tttaggaatg
    12901 taaatttaat tccattttat acaatatatc aatttatagt agatagtaat cttgacttta
    12961 tgaaagctac tgtaaatatt atagaaaata taggtatatt tattcctatg ggaatttttt
    13021 tacctatagt atgtaaaaat ctaaataaaa aaactataat tatagtaatt atacttgtta
    13081 gcctagcatt tgaattaaca caatatattt ttgctcttgg aagtagtgat atagatgatg
    13141 ttattttaaa ttcattaggt ggaataattg gaattaatat ttacataaac atgaataaat
    13201 tatttcctaa tgatattaaa agatttaagg ctataatagc tactagttta gttttaggag
    13261 ttttaggatt aggagttatt tctaaaaatt atcataactt actaactttt aaatttagac
    13321 ctgatagaaa aatatcaaaa atattaattg aagaaaatag ggaaataatt aaagatataa
    13381 ataaagatac agtagatata gttgggacat ttgagagctt taaaaaagga ataataacta
    13441 ttaaagcagg ttctaataac aaagtaaaga gaccagagaa tttaattgat tctgatggaa
    13501 atataagaat ttatttaaat gaaaatacaa aattagtatc ttatataatt accaaagaat
    13561 caaaaatgga tatagttaaa tatgaggaat ttgatgtgaa gaatttagat ttattaagga
    13621 gatatgatac tattaatgtt tggattgata aagaaaatca gccaaaggat aaacatggta
    13681 ttatggctag taaattatta attggattgt atgaataaaa tattaaacaa gaataaaaga
    13741 ataacaaata taaaaaacga aaaaactatt tctataatta tttttacgtt gtgcataaaa
    13801 taagaacatt agtgaaggag tagagataaa ttatggagat aataaaatat atcttgtact
    13861 tttttatata ttcattttta ggatggacag tagaaagtat aggatgttct atagcaagca
    13921 aaagaataat caacagaggt tttttaaatg gtccaatatg ccctgtttat ggttttggag
    13981 cagtaattgt gatatcacta ttaggaagat ttaataatgt agtaatagta tttctattag
    14041 gaatgatttt aactacgata ctagaatatt ttacaggatt tattttagaa accttatttc
    14101 atgctaaatg gtgggattat tctgacagaa aattcaatat aaagggtaga gtatgtttaa
    14161 aaaatgcaat atactttggt gtaatgtctg ttttaataat aagatttata catccattta
    14221 taaaatattt tgtaagtata attccatata gaatattaat ttcaatggct ataattacaa
    14281 cactttggac tatacttgat ttgattgtta ctattataac acttaaaaaa ttagatataa
    14341 agttaaactt actagacgat ataattacag accttaatga tataaatgtg aaattggata
    14401 aatttgatag aggagaaata caagctttat ttaaaacaat aaataacgac ggattagaag
    14461 ttagagaaaa aataaacaaa ataaatagta agttggaccg tatagagtct aatattattt
    14521 tacaaaaaag agttataaaa gcatttccac atataaaaca taaaaaacaa caagagcaac
    14581 tagaacattt taaaaaaatt attaatgaga aaaggtaatt atacaattta atgaagacga
    14641 atagaataat ggtatttata agattatttt cagaggactc tataaaaata gaatagagtc
    14701 ctttattttt tgaaaaataa tgtttatttg ataaaaataa aatatattgt ttctaaataa
    14761 caaatatttt gaaaattata aaaacatata ttgacaattt gtgtcaaaaa tactaacatt
    14821 aagtatataa agaattttat atgagaatat ctttataaat cgcaataatt ttagaacata
    14881 aatttattta aagaggggat gatttgccaa tgagcgagat aactagtcaa atgataagta
    14941 cagaagaaaa aaaatatgtt gctaaaactc aaaagatacc ttattatcca gtagcattta
    15001 aatcaggtga tggtgcaatg ctatatgatt atgaaggtaa tgaatatgta gattttttag
    15061 caagtgcagg ctctgcaaat gtaggtcatg gtaataagga aatctcacaa gcagttaaag
    15121 aacaaatgga tgatataaca caatatacac ttgcatattt ccatagtgat cctcctgtaa
    15181 aattagctga gaagcttgtg gaaatagccc ctggagataa tgataaaaaa gtactataca
    15241 gtgcaactgg ttctgcttgt atagatgctg ctataaaatt agcaagaggg tatactggaa
    15301 gaacaaagat aatatctatg tgtgaatctt atcatggaag tacttatgga gctatatcta
    15361 tatctgcttt aagtacaaat atgagaagaa aaatgggtcc attgttacca gaagtttatc
    15421 acttccatta tcctgataaa aatagaacag ctaaagaatg tttagatgag atagaatatg
    15481 cttttgcaca ctatctacca gcagaagagg tagctgcaat atttatagag ccaattgcag
    15541 gagatgcagg aataatagtg cctccagtag agtgggtaca aggtttaagt aaaatatgta
    15601 aagaaaatgg aatattactt gtaagtgatg aaatacaaca aggtatggga agaacaggta
    15661 agtggtttgg tatagaaaat tttggtgttg aagcagacct tatagttctt ggaaaatctg
    15721 ttggaggtgg attaccttta ggagcagttg ttggaagaac agaaataatg caaagtcttg
    15781 atgcaccagc acatttattt actttagctg gaaatacaac agtgtgtgtc gctgctttaa
    15841 aatctataga gataattgaa aaagaaaact tacttcaaaa gagtatagaa atgggagatt
    15901 atattaaagc aggatttgaa aaactaaaag aaaaatacga tataattgga gaaataagag
    15961 gaatagggtt atctatagga gttgatatag ttaaaggaaa aggttctaat gaaaaacatc
    16021 cagatgctac agctaagata tgttatagat gtatacaaac tggattaata atgatattct
    16081 taggacaatc tactttaaga gtacaaccac ctctagtaat aactaaggag caagtagata
    16141 aagcaatgag catcatagat tctgcaatag atgattattt aaatggtaga attggtgatg
    16201 aagtatatga agtaactcaa ggttggtaaa ataaatatta aatgaaaaaa agagttatct
    16261 caattttaga aagtaatttc tgaaatgaga taactctttt aagttaccca caaataagaa
    16321 aattgtttga ttcattaaag actatatttc ggatgtcgtt tttgtgagta tcagagacag
    16381 tattacgaga ataattacct ttattcgtac tatctgttaa tttagttata attaagatag
    16441 ctaaaagaat aagaattact gtgtataaag caataacata tggttttctt ttatatttgt
    16501 atttgttatt gaaaaaagaa tggccataat tatttttatt tactttagat gtatttgtat
    16561 tctttttctt gttacctttc tttttatcat ccttttttct atttttaggg taaggaatga
    16621 ctttgtgtgt attatcaagt ttgatatttt tatttttttg aatattgttt tccaggctag
    16681 cctttttttc tccaaattga atagttttat tggtattgtt gttatctttc aatgttaatc
    16741 tccctccctt aaactttccc tttagataat attactacta acctatggaa tatacaataa
    16801 ataatatata agtaataaaa ttttataggt ataaatctct ttctccacgc tctaaggcag
    16861 tcatattgtt agatactatg tttcttatat cttctctttc tatcttacct atttcttctg
    16921 cgataagttt tttacccata attttaagtt cttcatctcc ataatcgatt aaaaattcat
    16981 ttaatgtagt aagagcattt ggcgtacata cattatggat ttgtcgactt ttagctaagc
    17041 tcatgaatct atcgccagtt ctacctttac gataacaagc tgtacaataa ctaggtatat
    17101 atccatcagt aatcagttct ttaagcacct caacagggct tctatggtct ccaacttcga
    17161 attgttctgt attgtcacca tcttcatatg ctttatatcc tccaacacct gttagagaac
    17221 ctgcactaat ttgtgataca ccatatttta gtaactcatt tctcatttca gcagtttctc
    17281 tagtggacat tatgattcca gtaaaaggaa cagccaatct agttatagct actatttttt
    17341 tgaacatatc gtcagaaact aagtgaggaa aatcttctaa gctcatacct tcagcttttt
    17401 tcaatctagg gaaagatata gtatggaaac ctacaccaaa tttttcctct aagtgttcgt
    17461 tgtgcatcat aagtcctaga acttcaaatt tagggtcaga taaaccaaat aaaactcctg
    17521 caccaacatc atcaacacca gcttccatag ctctatcaaa agctgttaaa tggtaataat
    17581 agtcattttt tatagattga ccatgcattt ttataaatgt tggtttgtga taagtttctt
    17641 ggaataatat ataagttcct attccttttt cttttagtaa tttatactca tctacacttg
    17701 tagctgctat gttaacgttt acccttctta tatttccgtt ttcattatat gttgaataaa
    17761 ttgcatctaa gcaatctaag atgtaattta tatcacaatt tttagggtct tcaccagctt
    17821 ctagagcaag tcttttatga cccatttttt ctaatatttt aacctcttcc tttatctctt
    17881 ccatggtaag tttttttctt ttaaatttgt tgcatttact aaaaccgcaa taaacacatt
    17941 catttacaca gtagtttgat acataaagag gggcaaataa aaccactcta ttaccatata
    18001 tttcattttt tatttgccca gctatactaa ataatctatc tagttgtttt ttatcttcta
    18061 cttcaagaag tgtagctata tctttataac taagtttttc ccttctatca gccttatcaa
    18121 gtaccttttc aatatcatca gaagttgaat tttttgcatc ttctaataaa gaattaataa
    18181 gttcatggtt tatgaacatt tacaaacgcc tccattcaat attatcaccg cgagaatagt
    18241 caacttcaag tcctaatgac ttgatgtttt cttctaaact ttggtgatat tcacaagctt
    18301 cttgaccagt aaaggctttg ttatcgtaaa gagaatattg ttttctaaat tcttgaggag
    18361 aaaggtttgg cataattaca ttgcaaccag ctaaaagacc tgcatttcta ccactagggt
    18421 ttatagatgc caaggctgtt gtagcgggta ataaaacttt tggaagtaga agtcttgtaa
    18481 ttgaaagcat aagtaatgtc ttctctaaat ctccatgttt ataatcctta aaaattgtat
    18541 catggtgtgg aataaaaggt cctattccaa ccatatgagg atttaactct tttaggtata
    18601 ataaatcacg aacaaggtct ttgttgttct gaaatggtga ttcaaccata aatccagcac
    18661 ctacctgata accaatttct ttaaggtttt ttaggcattc ttttctagtt ctaagctcaa
    18721 tgtttggcgg atgtaatttt ttataatgac tgtctgtagc agtttcatgt cttaaaagat
    18781 atctatctgc accacataaa aagtattttt tatacgaatc ataactcttt tctcctagtg
    18841 acagagttat ggcacaatcc tcatatttat tttttatact tgaaacaatt tcacatattt
    18901 tatcatcagt aaaatatgca tcttcaccac cttgcaaaac gaatgttctg tatcctattt
    18961 tataacctat atcacaacat tcaagtattt catcaggtga aagtctgtat cttatgatat
    19021 ttttattaga agattgtatt ccacaatagt agcaattatt tttacaatag tttgtaagct
    19081 ctataagtcc tctcaagtag actctatttc cataatgttt atttctcatg tcgctagctt
    19141 gtttataaag atagtttctt aaattttgtt cgaagttata ttcctcattg tcgatatttt
    19201 ctattaaata tagtagttca tcaaaactta atgaattaat gctgtaaagt ttatctataa
    19261 agtatttaat cttattttta gtcatattca aatatgtaat tattaagtat agttaaattt
    19321 ttaataattg aaaagttcaa gtgatctttc caaaatacct tttacatatg ctattaagat
    19381 accatagttt acaataggta cattgaaaga ttttgccttt tctattctag ataacattcc
    19441 agctctattc atcatacaag ctccacagtg aactacaagg gcatatttat ttatatcttc
    19501 agtgaaggat actccagaac taaattcaaa agtaatattt ttgccagttt tctttctaat
    19561 catattagga atttttactg ttccaatatc atcagtttgt ctatgatggg tacatccttc
    19621 agccatcaag attttatcac catcttttaa attttctaaa gcataagctc cattaatcaa
    19681 ttctttaagg tctccctttt gtctagcaaa caatatagaa aaagatgtaa gaggaatatc
    19741 ttttggtgta tctttattta cttgtggaaa tacttgagag tcagtaataa caagttttgg
    19801 ttttttgcct aaattagata gagtttcttt taaactatct tcttttgtaa ctatagaaat
    19861 tgcaccatta tccaaaatat ctcttataac ttgctgttga ggaagtataa gtctaccttt
    19921 tggagctgct ttatctattg gaacaactaa aacaactaaa tcatttggtt caattaaatc
    19981 tgataccaat ttgaactcag tgctatcctt aggcaaaact tttattattt cattttttaa
    20041 attttcaatt ccaattttat ctgttgatga gacagaaaca actggacatt taactttatt
    20101 tttagttaag tttaaaattt ctgattgatt cttaatagta tcaattttgt tgagaattag
    20161 aatatgaggg atattcttat cattaaactt ttcaattagt gacaaatctt cttgtgatat
    20221 accaatttgg caatccacta ctagtaaagc tatatctgtc ttttctaaaa catctagtga
    20281 tttacctatt ctaagttcac caagttcacc aacatcatca agaccagcag tatctataag
    20341 aacacaaggt cctataggaa ggatttccat tggtctaaat actgggtctg tagtagttcc
    20401 agcaatatct gagactattg cagcactttg atttgttata gcatttatta tgctagattt
    20461 acctgcattt cttttaccaa agagacctat atgtactctt accgattgtg gagtagaatt
    20521 tagactcatt tgtactcacc accttaaact tctttttttg atatactagt ttttacagat
    20581 acatgaggta tgttgcccaa tttaccagtc aaactattaa tagtatccat ttcgccaaca
    20641 actgctatac atacgattga gacaccttct tcttcgcaag gaatgcccat tcttccttta
    20701 ataatacctt taaaacctga tacaacctca ttgaatttaa attgacattc ttttggctct
    20761 tccaaaatag cacttataac tgcaaccttt ttcataaata tcctcctaac tcagaaaata
    20821 tgtcttaaac aaatccaaaa tcaaaaaact tttctttgta aagaaaagtt tctacaaaag
    20881 aaaagttatt aattacacaa gtataatgtg ctatattaaa ctatttcctt acagattaga
    20941 taactctttt ctggtagggt tagcttgtaa aaatttaatt taacaacaag taactgaaga
    21001 aaatttttat acaatttata taaattataa taaaaattaa c
//
LOCUS       DAMJWO010000076        20714 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.078, whole genome shotgun sequence.
ACCESSION   DAMJWO010000076 DAMJWO010000000
VERSION     DAMJWO010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20714
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.078"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            358..669
                     /gene="rpsJ"
                     /locus_tag="PC366_002852"
     CDS             358..669
                     /gene="rpsJ"
                     /locus_tag="PC366_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HDF2578349.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            761..1390
                     /gene="rplC"
                     /locus_tag="PC366_002853"
     CDS             761..1390
                     /gene="rplC"
                     /locus_tag="PC366_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HDF2578350.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            1420..2043
                     /gene="rplD"
                     /locus_tag="PC366_002854"
     CDS             1420..2043
                     /gene="rplD"
                     /locus_tag="PC366_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001127258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HDF2578351.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNVIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2043..2333
                     /gene="rplW"
                     /locus_tag="PC366_002855"
     CDS             2043..2333
                     /gene="rplW"
                     /locus_tag="PC366_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HDF2578352.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTASFKKAVVKLTADSKEIEFFQGM"
     gene            2363..3193
                     /gene="rplB"
                     /locus_tag="PC366_002856"
     CDS             2363..3193
                     /gene="rplB"
                     /locus_tag="PC366_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HDF2578353.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3228..3509
                     /gene="rpsS"
                     /locus_tag="PC366_002857"
     CDS             3228..3509
                     /gene="rpsS"
                     /locus_tag="PC366_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HDF2578354.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            3541..3876
                     /gene="rplV"
                     /locus_tag="PC366_002858"
     CDS             3541..3876
                     /gene="rplV"
                     /locus_tag="PC366_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HDF2578355.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            3899..4714
                     /gene="rpsC"
                     /locus_tag="PC366_002859"
     CDS             3899..4714
                     /gene="rpsC"
                     /locus_tag="PC366_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HDF2578356.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            4750..5181
                     /gene="rplP"
                     /locus_tag="PC366_002860"
     CDS             4750..5181
                     /gene="rplP"
                     /locus_tag="PC366_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HDF2578357.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5183..5386
                     /gene="rpmC"
                     /locus_tag="PC366_002861"
     CDS             5183..5386
                     /gene="rpmC"
                     /locus_tag="PC366_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HDF2578358.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            5410..5664
                     /gene="rpsQ"
                     /locus_tag="PC366_002862"
     CDS             5410..5664
                     /gene="rpsQ"
                     /locus_tag="PC366_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HDF2578359.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            5690..6058
                     /gene="rplN"
                     /locus_tag="PC366_002863"
     CDS             5690..6058
                     /gene="rplN"
                     /locus_tag="PC366_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007885948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HDF2578360.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6082..6387
                     /gene="rplX"
                     /locus_tag="PC366_002864"
     CDS             6082..6387
                     /gene="rplX"
                     /locus_tag="PC366_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HDF2578361.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            6417..6959
                     /gene="rplE"
                     /locus_tag="PC366_002865"
     CDS             6417..6959
                     /gene="rplE"
                     /locus_tag="PC366_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HDF2578362.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEMISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            6977..7162
                     /locus_tag="PC366_002866"
     CDS             6977..7162
                     /locus_tag="PC366_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HDF2578363.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7195..7593
                     /gene="rpsH"
                     /locus_tag="PC366_002867"
     CDS             7195..7593
                     /gene="rpsH"
                     /locus_tag="PC366_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HDF2578364.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            7624..8166
                     /gene="rplF"
                     /locus_tag="PC366_002868"
     CDS             7624..8166
                     /gene="rplF"
                     /locus_tag="PC366_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HDF2578365.1"
                     /translation="MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8202..8570
                     /gene="rplR"
                     /locus_tag="PC366_002869"
     CDS             8202..8570
                     /gene="rplR"
                     /locus_tag="PC366_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HDF2578366.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            8591..9100
                     /gene="rpsE"
                     /locus_tag="PC366_002870"
     CDS             8591..9100
                     /gene="rpsE"
                     /locus_tag="PC366_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HDF2578367.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9115..9300
                     /gene="rpmD"
                     /locus_tag="PC366_002871"
     CDS             9115..9300
                     /gene="rpmD"
                     /locus_tag="PC366_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HDF2578368.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9333..9776
                     /gene="rplO"
                     /locus_tag="PC366_002872"
     CDS             9333..9776
                     /gene="rplO"
                     /locus_tag="PC366_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HDF2578369.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            9820..11088
                     /gene="secY"
                     /locus_tag="PC366_002873"
     CDS             9820..11088
                     /gene="secY"
                     /locus_tag="PC366_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HDF2578370.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11105..11755
                     /locus_tag="PC366_002874"
     CDS             11105..11755
                     /locus_tag="PC366_002874"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HDF2578371.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVDYYSKQGIIADIKGDQAIDKVFEDIVAALGSGK"
     gene            11756..12502
                     /gene="map"
                     /locus_tag="PC366_002875"
     CDS             11756..12502
                     /gene="map"
                     /locus_tag="PC366_002875"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HDF2578372.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            12524..12793
                     /locus_tag="PC366_002876"
     CDS             12524..12793
                     /locus_tag="PC366_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HDF2578373.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYDFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            12831..13049
                     /gene="infA"
                     /locus_tag="PC366_002877"
     CDS             12831..13049
                     /gene="infA"
                     /locus_tag="PC366_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HDF2578374.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13085..13198
                     /gene="rpmJ"
                     /locus_tag="PC366_002878"
     CDS             13085..13198
                     /gene="rpmJ"
                     /locus_tag="PC366_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HDF2578375.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            13351..13722
                     /gene="rpsM"
                     /locus_tag="PC366_002879"
     CDS             13351..13722
                     /gene="rpsM"
                     /locus_tag="PC366_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HDF2578376.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            13758..14156
                     /gene="rpsK"
                     /locus_tag="PC366_002880"
     CDS             13758..14156
                     /gene="rpsK"
                     /locus_tag="PC366_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HDF2578377.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14188..14811
                     /gene="rpsD"
                     /locus_tag="PC366_002881"
     CDS             14188..14811
                     /gene="rpsD"
                     /locus_tag="PC366_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HDF2578378.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            14889..15836
                     /locus_tag="PC366_002882"
     CDS             14889..15836
                     /locus_tag="PC366_002882"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HDF2578379.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            15857..16198
                     /gene="rplQ"
                     /locus_tag="PC366_002883"
     CDS             15857..16198
                     /gene="rplQ"
                     /locus_tag="PC366_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003357477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HDF2578380.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16318..17151
                     /locus_tag="PC366_002884"
     CDS             16318..17151
                     /locus_tag="PC366_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HDF2578381.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQ
                     L"
     gene            17139..18005
                     /locus_tag="PC366_002885"
     CDS             17139..18005
                     /locus_tag="PC366_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HDF2578382.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDISFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            17999..18802
                     /locus_tag="PC366_002886"
     CDS             17999..18802
                     /locus_tag="PC366_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDF2578383.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWP
                     YIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAIT
                     KQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            18834..19565
                     /gene="truA"
                     /locus_tag="PC366_002887"
     CDS             18834..19565
                     /gene="truA"
                     /locus_tag="PC366_002887"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDF2578384.1"
                     /translation="MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETS
                     LIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            19685..20116
                     /gene="rplM"
                     /locus_tag="PC366_002888"
     CDS             19685..20116
                     /gene="rplM"
                     /locus_tag="PC366_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HDF2578385.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20145..20537
                     /gene="rpsI"
                     /locus_tag="PC366_002889"
     CDS             20145..20537
                     /gene="rpsI"
                     /locus_tag="PC366_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003515879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDF2578386.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
BASE COUNT         8271 a         2443 c         4325 g         5675 t
ORIGIN      
        1 atggatttaa tataaaaaaa agaggggggt aactcctctc ttttttgttt tttgttgaca
       61 agtagcgcta aagcatatat actaaactag tgccttgaga cagattaaca atcaagttta
      121 aggttatgat gttgtaatag aaaataaaat tgaaaaaaac agaaaaaaaa cttgaaaaaa
      181 tgtaacagat gatataaaat ataatagtgt gcttgagaga ttaagaaaat aataattaaa
      241 tcctagtgaa atacgaactg atatcgattt aaaagttaca acacacccgg agcagtgtat
      301 cggtattggt tgtacgcaac ttgaaaatta aacacgtgat aaaggaggga aaacaaaatg
      361 gctaagaatg aaaaaataag aataagatta aaatcatatg atcacaaatt attagatttt
      421 tcagcaggta aaatagttga aactgctaaa aaggctggat cacaagtttc aggacctgtg
      481 cctctaccaa cagaaaaaca agttgtaact atattaagag ctgtacataa gtacaaagac
      541 tctagagaac aatttgaaat aagaactcat aaaagactaa tcgacatagc taatccaaca
      601 cctaagacag ttgactcatt aatgagatta gacttaccag caggtgtaga tatagaaata
      661 aaattataag aacccctaag atattatcct atagatgatt atcttagaat gattactcta
      721 aaagatgtaa tccgctgtaa gaattatagg aggtgctaat atgaaaggaa tattaggcaa
      781 aaaagttggt atgactcaaa tattcactga taaaggtgta gttatacctg taacagctgt
      841 tgaagcaggg cctatggtcg ttactcaaat aaaaacagtt gataaagatg gatacaatgc
      901 tatacaaata ggttttgaag atgctaaaga aaaagcttta aacaaaccta aaaaaggaca
      961 tttagctgct gctaatgttt taaagaaaca tttaaaagaa tttagagtag attctgtaga
     1021 aggatacaca gtaggacaag aaataaaagc tgatgtattt gaagcaggtg caaaaataga
     1081 tgttactgga ataagtaaag gtaagggatt ccaaggtcca ataaaaagac atggacaaag
     1141 tagaggtcct gaaactcatg gttctagata ccacagaaga ccaggttcaa tgggagcttg
     1201 ttcttaccca ggtagagtat ttaaaaacaa aaaattagct ggacatatgg gaagcgtaaa
     1261 ggtaacagtt caaaacttag aggttgttaa agtagatgct gacaagaacc ttatattagt
     1321 taaaggagct ataccaggag ctaaaggttc agtagtaact ataaaagaag ctataaaggt
     1381 ttctaaataa tgactaacct agagaaagga ggaataacaa tgccaaaatt aaatgtacta
     1441 aatgttagtg gacaaaacgt tggagaaata gaattatcag attctatatt tggcgtagaa
     1501 gttaatggac atgttttata cgaagttgta aaaaatcaat tagcaaataa gagacaagga
     1561 actcaatctg ctaaaactag agcagaagtt agaggtggcg gaagaaaacc ttggaaacaa
     1621 aaaggaacag gtagagcaag acaaggttct acaagatctg tacaatgggt aggtggagga
     1681 gttgcttttg cacctaaacc aagaagctac aaatatacat tacctaagaa ggtaagaaga
     1741 ttagctatga agagtgcttt atcttcaaaa gttcaaaata gtgaagttat agtattagat
     1801 gcattaaaca tggatgctcc taagactaaa gaatttgctc aaatattaaa caatataaat
     1861 gctgctaaaa aagctttagt agttatagct gacaaaaacg ataacgtaat aaaatcagct
     1921 agaaatatag aaggtgttca aactgcatta gttaatacta tgaatgtata tgatatatta
     1981 aaatacgatt catttataat aactacagat gctgttaaaa aagtggagga ggtgtacgca
     2041 taatgactaa tccacatgat gtaataataa gaccagttgt aactgagcac agtatggctg
     2101 aaatgggtga aaaaaaatac acttttgttg tggctaaaga tgcgaacaaa actgaaataa
     2161 aaaaagcagt agaaaaagta ttcggagtta gtgttgataa agtaaatact ttaaactacg
     2221 atggaaaagt taaaagaatg ggtagaactc aaggaagaac agcaagcttt aagaaagcag
     2281 tagttaaatt aactgctgat agtaaagaaa tagaattctt ccaaggaatg tagtattata
     2341 acaaacgaag gagggaaaac agatggctat aaaaaagttt agaccaactt ctcctgcctt
     2401 aagacaaatg acagttttag tttctgatga aataacatgt aatcaaccag aaaaatctct
     2461 tttagttaac ttaaagaaaa atgctggtag aaacgtacat ggtagaataa ctgttcgtca
     2521 tagaggtgga ggacaaaaaa gaaaatatag aataatagat tttaaaagag ataaagatgg
     2581 tatacctgct aaggttgcta ctatagaata tgatccaaac agaactgcaa atatcgcatt
     2641 attaaactat gctgatggag aaaaaagata tatattagct ccagttggaa ttaacgttgg
     2701 agatactata ttatcaggat taggtgctga tataaaacca ggaaactgtt tagcattaaa
     2761 agatatgcca gttggtacta tcattcataa tatagaatta aagccaggaa aaggagctca
     2821 attagttaga tctgctggag tttctgcaca attaatggct aaagaaggaa aaaatgcttt
     2881 attaagatta ccatcaggtg agatgagatt agtaagcata aactgtaaag ctactatagg
     2941 tcaagttgga aatatagagc atggtaacgt agttatcggt aaagcaggta gaaaaagaca
     3001 tatgggaata agacctactg taagaggttc tgtaatgaac cctaatgacc atccacacgg
     3061 tggaggggaa ggtagatctc caataggtag accatctcct gttactccat ggggtaaacc
     3121 agctcttgga tacaaaacta gaaagaaaaa taaagcttca aataaactaa tagtatcaag
     3181 aagaactaag tagtaaattt atttttgctc ggaaaggagg aatataaatg tcaagatcaa
     3241 ctaaaaaagg gccttttgtc catgcaagac ttttaaagaa gatagaagct atgaatgcta
     3301 gtggaaataa agaagttata aaaacttggt caagatcttc aactgtattt ccacaaatgg
     3361 tagaaaacac tatagctgtt catgatggaa gaaaacatgt tccagtatat ataacagaag
     3421 atatggttgg acataaatta ggtgagttcg ttcctactag aactttcaaa ggacataagg
     3481 atgacgaaaa atctaataag agaaaataat taaattatga ctaagaaagg aggaataaca
     3541 atggaagcaa aagctactgc taaatacgta cgtgtatcac caagaaaagc aggccaaata
     3601 tgtgaccttg ttagaggaaa gaatgttgat gaagcattag caatattaaa gtttactcca
     3661 agaggagcag cttcaataat agctaaggtt gtaaaatcag ctaaagctaa cgcagaaaac
     3721 aatcacgaaa tggatactga aaaattatat atagcatcaa tagttgctaa tcaaggacca
     3781 acaatgaaga gattcatgcc tagagctatg ggtcgtgcaa ctacaataag aaaaagaact
     3841 tctcatatag aggttgttgt taaagaaaaa aaataattaa tagataggag ggaaagtaat
     3901 gggtcaaaag gttaatccac acggcttaag ggtcggtgtt ataaaagatt gggactcaag
     3961 atggttcgct actgataaaa aagagttcgg aaacttatta ttagaagacc ataatatacg
     4021 taaattctta aagaaaagat tatactcagc tggagttgct aagatagaaa tagaaagatc
     4081 agctaacaaa ataaaaatgg acttacacgt tgctaagcct ggtgtagtta taggaagagc
     4141 tggtgcagga atcgaagcat taaaagctga attagaaaaa atgacaaaga aaactataat
     4201 agttaatata gtagaagtaa gaagtacaga taaaaatgct caattagtag ctgaaaatat
     4261 agctttagct atagagagaa gggttgcttt cagaagagca atgaaacaag ctatacaaag
     4321 agcaatgaaa tctggtgcta aagggataaa agtttctgct tcaggaagat taggtggagc
     4381 tgaaatggct agaactgaag gttatagtga aggaaatgtg ccactacaaa ctttaagagc
     4441 agatatagat tatggtttcg ctgaagctga tacaacttat ggaaaaatcg gtataaaagt
     4501 ttggatatgt aatggtgaag ttttaccaac tagagacggt gtaaatccaa gagaagaaag
     4561 cagaaagagc gatagaagag acaacaagag agataataga agaaacgata gaagaggaaa
     4621 tgacagaaga ggaaatgata acagaggaaa ctacagagga caaagacctc aaggtggatc
     4681 aagacctcaa agaactgaaa acaaaggaaa ttaataatag ttaggttcaa ggaaggagga
     4741 aaaatactca tgttaatgcc aaaaagagta aagcgtcgta gagttcatag aggaagcatg
     4801 gctgggcaag ctcataaggg taataaagtt acttatggtg agtttggatt agtagcatta
     4861 gaagcttctt ggataacttc taatcaaata gaagctgcca gaatcgcgat gactagatat
     4921 ataaaaagag ggggaaaggt ttggataaaa atattccctc ataaaccagt aacaagaaaa
     4981 ccagcagaga ctcgtatggg tgcagggaaa ggttctccag aatattgggt agctgtagtt
     5041 aagccaggaa gagttatgtt tgaattagca ggtgtttctg aagataaagc aagagaagct
     5101 atgagacttg ctgcacataa attaccaatc aaatgtaaat ttgttaaaaa agaagattta
     5161 gaagtaaagg gtggtgaata ggatgaaagc taaagaatta agagatttaa caagcgaaga
     5221 gctaatgaac aaattaaacg acttcaaaag tgaattattt agcttaagat tccaattagc
     5281 tactggtcaa ttagaaaata cagctagaat aaagtttgtt aagaaggata tagcaaaagt
     5341 taaaactgtt cttgctgaaa gaaagttata cgaaactaga gcttaatttg gaaaggaggc
     5401 tttttaaaca tggaaagagg aagaagaaaa gttagaatag gccgtgttgt tagtgataag
     5461 atggataaaa caatagtagt agctgttgaa gaattcgtac gtcatccact atataataaa
     5521 cgtgttaaga gaactaagaa attcaaggct catgatgaaa agaatatatg taacatcgga
     5581 gatagagtta aaataatgga aactagacca ttatctaaag ataagagatt cagactagtt
     5641 gaagttgttg agaaagttaa gtagtttttg aagaaggagg gattacgata tgatacaaca
     5701 agaatcacgt ctaagagttg ctgataactc aggagctaaa gaacttttat gtatacgtgt
     5761 tctaggcgga agtaaaagaa gatatggtaa cataggcgac gttatagttg ctactgttaa
     5821 aagtgcaaca cctggtggag ttgtaaaaaa aggtaaggtt gttaaagctg ttatagtaag
     5881 aagcaaacaa ggcgtaagac gtaatgacgg aagctatata tcttttgatg aaaatgctgc
     5941 tgttataata aaggacgata aaactccagt aggaactcgt atattcgggc ctgttgctag
     6001 agagttaaga gacaatgaat tcatgaaaat agtttctctt gctccagaag tactataatt
     6061 aaggaggtgc aataggacat gatgcgtgtt aaaaaaggtg acactgttgt agttatagca
     6121 ggtaaagata aaggtaaaaa aggttcagtt ttaaaggtat atcctaaaac tagcaaagtg
     6181 ttagttgaag gtgtaaatgt aataactaaa catcaaaaac caagtgctat gaaccaacaa
     6241 ggtggaataa taaataaaga agccccaata cacatatcta atgtaatgcc atttgatcct
     6301 gaaacaggaa aaggcgttag agtaagatat gaagtaaaag atgggaacaa agtaagagta
     6361 tcagcaaaga gcggaaaaga attataataa atattgcttg aaaggaggga ccttaaatgg
     6421 cttctagatt acaagaaaaa tacatgaaag aagttgctcc tgctttaatg gagaaatttg
     6481 gatacaaaaa cgtaatggag atacctaagt taaataaaat agttattaac atgggtatag
     6541 gtgacgctag agaaaatcca aaaggattag aaaaaggcgt tgaagaatta gaaatgatat
     6601 caggacaaaa gcctgttata actaaagcta gaaaatctgt tgctaacttc aaattaagag
     6661 aaggaatgcc aataggaaca aaagttacat taagagctga caaaatgttc tactttatgg
     6721 acaaattagt ttcagtttct ttaccaagag ttagagattt tagaggagtt aaccctaatg
     6781 cttttgatgg tagaggaaat tatgctttag gagttaaaga acaattaata ttccctgaaa
     6841 tagaatatga taaaatagat aaagtaagag gaatggatat aatatttgtt actacagcaa
     6901 aaactgacga agaagctcgt gaattattaa aattattagg aatgccattt tctaagtaag
     6961 caaaggaggg attcccgtgg ctagaaaagc gatggttgtt aagcaacaaa gaaagcaaaa
     7021 gtacgctact agagaataca ctagatgtac tatatgcgga agaccgcatt cagttttgaa
     7081 aaaatttggt atatgccgta tatgctttag agaattagct tataaaggtc aaatacctgg
     7141 tgttagaaaa gcaagctggt agaagcttga ttagaatgga aggagggcaa caaaatgaca
     7201 atgacagatc caattgcaga tatgcttact cgtataagaa atgctaatgt tgttaagcat
     7261 gaaactgtag atgttccagc ttctaatatg aagaaagaat tagctagaat cttattagaa
     7321 gaaggtttca taagaggtta tgatgttata gaagatggaa aacaaggtat cataagaata
     7381 caattaaagt acggacaaga aggcgaaaga gttataacag gtcttaagaa aatatctaag
     7441 cctggaatga gagtttacgc tgctaaccat gagataccaa aagtattaaa cggattagga
     7501 atatcagtta tatctacttc aaaaggaata ttaactgaca agcaagctag aaaagaaaat
     7561 gttggtggag aagtaatctg ctacgtttgg taattaatat gaacaatgta aggaggtgcg
     7621 accatgtcaa gaataggtgt taagccaata ataataccag caggtgttga agttactata
     7681 gctgaaggaa atttagttac agtaaaaggt ccaaaaggaa ctttaactaa acaattaagt
     7741 gctgagttaa acataaaaaa agaagaaaat acaataatgg ttgaaagacc aactgataat
     7801 aaaaaacata gatctttaca cggactaact agaactttat tagataatat ggttgtaggt
     7861 gtaaatactg gtttcgaaaa gaaattagaa ttaaaaggtg ttggatatag agctcaaaaa
     7921 caaggaaaga aattagttat gaacttaggt ttctctcatc cagttgagat ggaagatcca
     7981 gaaggaataa ctgttgaagc tccaaaccaa acagagttaa tagtaaaagg tatagacaag
     8041 caattagtag ggaattatgc tgctaagata agagcttgga gaaagccaga gccatacaaa
     8101 ggtaaaggta taaaatacgt tgatgaagta atcagacgta aagaaggaaa aactggtaaa
     8161 aaataatacc aaaacttaaa cgctagaaag gagtgagcta ggtgttaaaa aaggctgata
     8221 aaaatgctaa tagacttcaa agacataaga gagttcgtag aaaaataagc ggtacttctc
     8281 aaagaccaag attatgtgta tttagaagtg ctaacaatat atatgctcaa ataatagatg
     8341 acacaaaaag agtaactcta gttgctgcat cttctttaga agcagaagtt aagagtgctg
     8401 tcaatcatac aggaaacaag gaagcagcta agaaagttgg agaattagtt gctaaaaaag
     8461 ctgttgaaaa aggaatcact gaagttgtat ttgacagagg tggatactta tatcatggaa
     8521 gaattcaaga attagctgaa ggtgctagag aagctggtct taagttctaa tacgaaggag
     8581 ggaaaaatac atgctacgtc gtaagccgat agatgcagga caacttgact tacaagaaaa
     8641 agttgttgaa gtaagacgtg ttactaaggt tgtaaaaggt ggtagaaatt tcagatttgc
     8701 agcattagta gttgttggag atgaaaacgg acacgttggt ataggtgctg ggaaagcaat
     8761 ggaagtacca gacgctataa aaaaagcagt tgaagatgct aagaaaaatc taatagtagt
     8821 gccaatagtt gggactacaa ttcctcacga agtacgcgga cactttggtg ctggaaatat
     8881 attaataatg cctgctgtag aaggtacagg agtaatagct gggggacctg ctagagccgt
     8941 acttgagcta gctggactaa aagacgttag agctaaatct ttagggtcta acaatccaag
     9001 aaatatggta aatgctacaa tagaaggact taattctcta aaaacagttg aagatatagc
     9061 taaacttaga ggtaaaaaag ttgaagaact tctagggtaa ggaggtagtg taaaatggct
     9121 aaattacaaa taaagttagt tagaagtgtt ataggaacta ctcctaacca aaaaaagaat
     9181 gttgaagcgt taggattaag aaaaagagaa caagttgttg taaaagaaga caatgctcaa
     9241 acaagaggta tgataaataa agtaagtcac ttattagaag taactgaaat agctgaataa
     9301 tttttataaa gtagtgcaag gaggtgcaat ccatgaagtt acatgagtta aaacctgctg
     9361 aaggtgcagt aagagctaag agaagattag gtagaggtac tgcaactgga caaggtaaaa
     9421 ctgcaggacg tggacaaaaa ggtcaatggt ctcgttctgg tggtggagta agagtaggat
     9481 ttgaaggtgg acaaatgcca ctagctagaa gacttcctaa gagaggtttc aataacatat
     9541 ttaagaaagt ttacacagaa gttaatgttg aagttttaaa cagatttgaa aatggaacag
     9601 aaataactgc agaattatta aaatctacta aaactataag caaaataggt aaagacggaa
     9661 ttaaaatctt aggtgaaggt aatttagaga aagctttaac tgttaaagct gctaaattta
     9721 cagcttcagc tcaagaaaaa atagaaaaag ctggtggaaa agcagagtta gtataataac
     9781 ctgctaatct cctagccagt acaggcgggg tgaattagcg tgctgtcaaa attaaaacaa
     9841 gcttggaaga ttaaagcagt aagaaaaaaa gtaatgtata cacttatgat gatcgtgata
     9901 ttcagaatag gtactactat accagttcca ggcatagaca ctagtattat acaaaagatg
     9961 gtaggcggca atagtctact ttctctgtat aatatgttta ctggtggagc atttagtaac
    10021 ttttcactat ttgctttagg tataagtcca tatatcactg catcaatcat aatacaactt
    10081 ctaacagtag gttttgaaag tttagcagaa cttcaaaaat ctggtgaaga aggaaagaaa
    10141 aaaatcaata agtacactaa atatacagca ctagctctag cagttgtaca agctttggga
    10201 attacattag gaattgtaag aagtgcttta atatcaaata gtgtgttttt tatcacaact
    10261 gttgtaataa cattagtttc agcaagtatg ttagtaatgt ggattgggga caaaattact
    10321 gaaaaaggaa tcggtaatgg tagttcagta ataatatttg caggtataat atcaagaata
    10381 cctacagatg ttattaaaat atcgcaacaa gttaaatctg gcgaagttgc accttgggtt
    10441 atagtgattc tagctgtagt tatattactt acagtaacag gagttacatt tatacaagaa
    10501 gcaactagaa agatacctgt acaatatgct aaaagagttg ttggaagaaa aatgtatgga
    10561 ggacaaagtt ctcatatacc aatgaaagtt aaccagtcag gagttatgcc tataattttt
    10621 gctagttcac ttttagcttt ccctcaaaca atagctatgt ttatgggtcc aaatgctcag
    10681 gcttttgttc aaaaatactt aagtatggca acagaacaag gattttggac atatagatca
    10741 attgagattc tacttataat tttcttctca tatttttata caactgtatc atttaataca
    10801 gaagacatat ctaaaaatat gaaaaataat ggtggattta taccaggtat aagaccaggt
    10861 gagcctacta tggattattt aaatagaatt ttaactagat taactttagc tggagctact
    10921 ttcttagcaa taattgctat ggtgccagct cttacaacac attatatgaa agtaaatatg
    10981 agtctagctg ggacttcatt gctaatcgtt gttggagttg ctttggagct taagagacag
    11041 ttagagtcaa acttagttat gagaagctat caaggtttct taaaataaaa tggagatgga
    11101 taatatgaga ataatattac ttggacctcc aggtgctggt aaaggtactc aggcggcagg
    11161 aatagtagaa aaatacaata tacctcatat atcaacagga gatatattca gaaagaatat
    11221 aaaagaggga acagaacttg gaaaaaaagc taaagaatac atggaccaag gtttattagt
    11281 accagatgag ttaactgtag gtttagttac tgatagaata tctcaagaag attgtaaaaa
    11341 tggatttatg ttagatggat ttccaagaaa tgtagcacaa ggagaacatt tagatatctt
    11401 cttaaaaaat gctggtatat cactagataa agttgtcaat attgaagttg ataagagtat
    11461 attagtgtct agagcagttg gtagaagaat atgtaagtct tgtggagcta cttaccatgt
    11521 tgagtttaat cctcctaaag tagaaggtgt atgtgatgta tgccaaggag aattatatca
    11581 aagagctgat gataatgaag aaactgtatc taagagaata caagtttatc tagatgaaac
    11641 taagccttta gtagattatt atagcaaaca aggtataata gcagatataa aaggtgatca
    11701 agcaatagat aaagtatttg aagatattgt cgcagcctta ggaagtggaa aataaatgat
    11761 tatcttgaaa tcaaaaaaag aaatagaact tttaagagaa gcaggtaaaa tagttgctga
    11821 cactcatgaa gttttaagaa aagctatttc tccgggaata tctactttag aattagataa
    11881 aatagctgaa gagaatataa gaaaatacaa tgcagagcct tcttttaaag gatatggagg
    11941 ttttccagga agtatatgtg cttctatcaa tagagaggta gtacatggta ttccaggaga
    12001 aactatatta caagaaggtg acattgtaag tttggatata ggagcctatt ataaaggata
    12061 tcatggtgat tctgcgaaaa ctcacggagt aggcatgata tctgaagaag ataggaaatt
    12121 gatagaagta actagagaaa gcttctatga aggaataaaa tttgctaaat taggatatag
    12181 actttcagat atctcacacg cagtacaaac acacgttgag aaacatggtt tctcggtagt
    12241 tagagattta gtgggtcatg gagttggagc aaatcttcat gaagacccac aagtacctaa
    12301 ttatggactc ccaggaaaag gaccaagact tagagaagga atggttattg ctatagagcc
    12361 aatggttaat gcaggtcgtt atcatgtaaa gactctatca gatgggtgga cgactgttac
    12421 aatagatgga aaaaaatcag ctcattatga gcatacgata gcaattactg aacatgaacc
    12481 tttgatattg acaaagttgt aatttaaaaa gtaggtgaaa aaagtgctat cagataattt
    12541 aagtataggt caagttgtta aagtttcatt aggacgagat aaaggaaatt tattctttgt
    12601 agtcaaaata attaataatg aatatgtatt aatagctgat ggaaaaaaga gaaaacttga
    12661 caaacctaag ttaaagaaag tgaagcactt aaaaaaatat gattttatta atgatgaagt
    12721 tagaaaaaga gtagtatctg gacaagagat tacagattct tttttaagag ctgaacttac
    12781 taagttaaat tagataattt aacttattga aatggagggc tggttagtta atggccaaaa
    12841 aagatgttat agaattagaa ggtacagttt cagaagcttt acctaatgct atgttcaaag
    12901 ttaaactaga aaatggacat gagatattat gccacatttc tggaaagcta agaatgaact
    12961 tcataagaat tcttgaaggt gacaaggtga atgttgaact ttctccatat gaccttacaa
    13021 gaggaagaat tacttggcgt aagaagtaga ctatattaat atttagtcta aggagggatt
    13081 aataatgaag gttagaccat cagtaaaacc aatatgtgaa aaatgtaaag taataaaaag
    13141 aaaaggaaaa gtaatggtta tctgtgaaaa tccaaagcat aagcaaaagc aaggataaga
    13201 aattattact agcattttgt taaattttat agtataatac tatattgtga tgttaacaaa
    13261 agaacgttaa aatcgttgaa caatctggcg taggattggc atatgatgtg aagttttaaa
    13321 cactaaaaac tatgtgtagg aggtgcgatc atggcaagaa tagctggggt agatttacct
    13381 agagaaaaaa gagcggagat aggcttaact tatatatatg gtataggtaa agcaactgct
    13441 aacgaaatat tagctaaggc tgagataaat ccagatacta gaataaaaga tttatcagaa
    13501 gatcaagtta atgagttaag aaaagttata gatgacgatt tcttagttga aggtgactta
    13561 agaagagaaa ttgctttaaa cataaagaga ttaagagata taaaatgtta tagaggaata
    13621 agacacgcta aaggtcttcc attaagagga caaagaacta agactaatgc tagaactaga
    13681 aaaggtccta gaaaaacagt atctcgtaaa aagaaaaaat aaataaataa taactagatg
    13741 aaggagggaa aaggaaaatg gctaaaccaa aaaagaaagt tacacgtatt agaagaagag
    13801 aacgtaaaaa tatagaacgt ggtcatgctc atatacaatc aactttcaat aatacaataa
    13861 taactttaac tgacgttcac ggaaatgcta tatcttgggc aagttctgga caattaggat
    13921 tcaaaggatc aagaaaatca actccatttg catctcaaat ggctgctgaa acagctgcaa
    13981 aagctgcgat ggaacacgga ctaaaaagtg ttgaggtatt cgtaaagggg ccaggttcag
    14041 gaagagaagc tgcaataaga gctttacaag caactggact agaagtaact atgataaaag
    14101 acgttactcc aatcccacat aacggatgca gaccaccaaa gagaagaaga gtgtaattaa
    14161 taagagtaca ataggaggtg tagataaatg gcaagatata caggtgcatc atgtagacaa
    14221 tgccgtagag agggaatgaa attattcctt aaaggtgata gatgttatac agacaaatgt
    14281 gctatagtaa aaagaaacta tgctccaggt caacatggcc aaggaagaaa gaaagtttct
    14341 aactatggat tacaattaag agaaaaacaa aaagttaaaa gaatatatgg agttttagag
    14401 actcaattta gaaatttata tgaacgtgct gaaaatatgc ctggtaaagc aggtgagaac
    14461 ttattaagtt tattagagag aagattagat aatgtagttt acagaatggg actagcatct
    14521 tctagaaaag aagctagaca attagtgact catggtcatt tcactttaaa tggaaataaa
    14581 gtagacatac cttcattaat agttaaggtt ggagatgtta tagaagttaa agagaaatca
    14641 agatcttctg caaaattcaa aaatttagta gaagttaact caagaatagc tcctaagtgg
    14701 ttagaagcta atgtagaagg aatgacagca aaagtagttg gtgttccaac aagagaagat
    14761 atagatcttg agatagcaga gcacttaatc atagaacttt actctaaata ataagcacac
    14821 ttttaaaaat tattttaaaa ttttgtttac cctcagtgga ttactgaatt ttaaggaggg
    14881 ttttgtccat gatagaaata gaaaagccaa aagtagatat agttgagctt agcgaagact
    14941 atagatatgg taagtttgtt atagagcctc tagaaagagg atatggaata actataggta
    15001 acgcattaag aagaatatta ttatcatcat taccaggtgt agcagtgaat gctataaaaa
    15061 tagatggagt tcttcatgaa ttttcaacaa tacctggtgt taaagaagat gttactgaga
    15121 taatattaac tttaaaagag ctttcagcaa ctatagatgg tgaaggaagt agaacactta
    15181 aaatagaagc tcaaggacca tgctctatca caggtgcaga tataatctgt cctccagatg
    15241 ttgaaatatt aagtaaagat ttagcaatag ctacattaga tgataatgct aaacttaata
    15301 tggagatatt tgtagataaa ggtagaggtt atgtttctgc tgaagaaaat aaaacagaga
    15361 atgttccaat aggtgtttta cctgtggatt caatatatac tcctgttgag aaggttagtt
    15421 atcatgtgga aaacacaaga gttggtcaaa aaacagatta tgataaatta gtactagaag
    15481 tttggactaa tggtagtata aatcctcaag agggaatatc attagctgca aaggtattag
    15541 ttgagcattt aaacttattt atagacttaa ctgaacatgt aagtagtgtt gaaatcatgg
    15601 tagaaaaaga agaagatcaa aaagaaaaag ttcttgaaat gactatagaa gaattagatt
    15661 tatcagttag atcatataac tgtttaaaga gagcgggaat taatacagtt gaagaattag
    15721 ctaataaatc tgaggatgat atgatgaagg ttagaaacct aggtaagaag tcattagaag
    15781 aggtaataca aaaactagaa gaacttggat tgggattaaa accaagtgaa gaatagcgag
    15841 caaaggaggg ataagaatgg ctaagtaccg taaattagga cgtgaaacag ctcacagaaa
    15901 ccttatgtta agaaacttag taacttgctt actaagaagt ggaagaatag aaactacagt
    15961 gactagagcg aaagaaactc gtagaatggc tgaaaagatg ataactcttg ctaagagagg
    16021 agatcttcat gctagaagac aagttttagc ttatgttatg gatgaaacag tagttaataa
    16081 cttattcaca gatttagctc caaaatatgc tgagagaaat ggtggataca ctagaataat
    16141 aaaaataggg ccaagaaaag gcgatgctgc tgaaatggct tttatagaat tagtatagta
    16201 aggaaaggat taggcttgat ggcttaatct tttttttatt tttttgacta aggtatgata
    16261 taataatgtg taaaatgatt tttataagtt attgcttact aaaaggagta tgagttaatg
    16321 gataatatag taaaggtaaa taatatttcg tttgagtata ttacagatga agcaaaactt
    16381 aaagcaatag ataatttaag cctagatgtt aaaaaaggag aatttgttgc gataatagga
    16441 cataatggtt ctggtaagtc tactttatct aaaaacttaa atgctattct tatgcctact
    16501 gaaggaaata ttcttattga tgatatggat actaaagaag aagaaagatt atgggatata
    16561 agacaaactg caggcatggt atttcaaaat ccagataatc aaatagttgc tactatagta
    16621 gaagaagacg ttgcatttgg acctgagaac ttaggtatag aaccaaaaga aataagacga
    16681 attgtagagg agtctttaaa aagtgtaggt atgtatgatt taagagatag acagcctcat
    16741 ttgttatcag gaggtcaaaa gcaaagagtt gcaatagcag gaattattgc tatgaggcct
    16801 aaatgtataa tatttgatga agcaacagca atgttagatc catctggaag aaaagaagtt
    16861 atgaaaacaa taaaaagact taataaggaa gaaaatataa ctgttataca tataacgcac
    16921 tttatggaag aagcagtaga agctgataga gttgtagtta tggaaaaagg aaagaaaatc
    16981 ttagagggaa ctcctagaga agtattcagt aaaataaaga tgttaaagga aatcggttta
    17041 gatgtacctt gtatgacaga gttatctagt ttattaatag aagaaggtat aaatattagt
    17101 agtgatatat taactgtgga tgagatggtg atggaattat gtcaattata gtaaagaatt
    17161 taacacatat atataatgaa gggatgcctt ttgcaagtaa ggcacttgat gatatttctt
    17221 ttgagattaa agatagagat tttgttggtc ttataggtca tacaggctca ggaaaatcta
    17281 cattaataca acatttaaat ggattactaa agccttcctc aggagaaata tttataaatg
    17341 attttaatat aacagataaa aacttgaatt taactgagat tagaaaaaga gtaggggttg
    17401 tatttcaata tccagaatac caattgtttg aagaaacgat tgataaagat atagcttttg
    17461 gaccctctaa tttaggctta gaggagtctg agatacataa cagggtaaaa gcatcaatgg
    17521 aagctgtagg acttgattat gagggattta aagacaaatc tccttttgaa ttatctgggg
    17581 gacaaaagcg tagagtagca attgctggag ttatagccat gaacccagaa gttctcatat
    17641 tggatgaacc aactgctggt cttgaccctg gtggaagaga tgaaattttt aacttaataa
    17701 aagacttaca tgaaaaaaag aatatgacta taatactatc atcacatagt atggatgata
    17761 tggcaaagtt agcaaaaact ttaattgtta tgaatcatgg tagcgtagaa tttatgggaa
    17821 ctcctagaga agtgtttaaa tcaaatgcta gtaaattaaa agatatagga ttagatattc
    17881 cacaagtttt agagcttgca ttgaaattga gagaaaaagg ctttgacatc agtgaggata
    17941 tattgacttt agaagaagca aaacaggaaa tattaaaagt tgtgagagga cgaggattat
    18001 gttaaaagat ataactatag ggcaatacta cccaacaagt tctgctattc ataaattaga
    18061 tccaaggata aagcttgtag cgacaattgt atttatggta tctatatttg tagtaaataa
    18121 attttggcct tatatagtag ttttattatg tttattagct atgataaaat tggctaatat
    18181 accagtcaaa tatattgtta agggtgttaa acctcttaaa tggattattt tgtttacatt
    18241 tcttataaat atttttttct taccaggtga tgaaatatgg tcatttggat ttttagctat
    18301 tacaaaacag ggtctaagac aagcaatttt tatggcaata agattaatat ttttagtagt
    18361 tggtacatca ttgcttactt taacaacttc accaatagaa ttaactgatg gaatagagag
    18421 attgttgaat ccatttaaga aaattggttt gccagttcat gaacttgcaa tgatgatgac
    18481 aattgcttta cgttttattc ctacattgtt agatgagaca gacaaaataa tgaaggctca
    18541 gatgtctaga ggtgcagatt ttgaaagtaa gaatcttata aatagagcaa agaatttagt
    18601 accacttttg gtacctttat ttgtaagtgc atttagaaga gctgatgaat tggctatggc
    18661 catggaggcc agatgttaca gaggtggaca taataggact aagatgagag agtctgttat
    18721 atcaagaagg gattatatgg catgtgtatt tcaggttgtt tatctgggag caattatagc
    18781 tactagattt atagcaattt aattaataag ttatagatat aatgaggtaa agtatgagaa
    18841 atataaaaat taaaatccaa tacaatggta agaattattg tggatggcaa aagcaacctg
    18901 attctttagg gatacaaggt acaattgaaa gggctatata tgatataaca aaagaagaaa
    18961 ccagtcttat agggtctggt agaactgatt caggagttca tgctattggt cagattgcaa
    19021 attttaaaat taattcaggt ataagtatag aaagtatacc aatggcacta aatgccaagt
    19081 tgccaaaaga catatcagtt atagaagcat gtgaagtaaa tgatgatttt cactccagat
    19141 acagtgcaaa aggtaaaaca tataaatatt tagtatataa tagcaagttt agaaatccaa
    19201 tacttagtga gatatcatat caagtaaaat atgaacttga ttttgataaa atgtgttcag
    19261 aagcaaaaag tttattagga acacatgatt ttaaaggttt tatgagttct ggttcatctg
    19321 taaaagatac agttagaacg atatatgata ttgatataag taaaaaagat gacttgatta
    19381 cttttgagat tagtggtaat ggttttttat ataacatggt gaggattatt gttggaacac
    19441 ttgttgatat gggtcgtggc agaattaacg aaccattttt agatataata caatcaaaaa
    19501 ctaggtcaag atgtggacat acagctccag cacaaggatt atttctcaaa aaagttcatt
    19561 attaacttga cacaccaggc tacatgtatt aaaatatatg agaatgtgtt aataagtcca
    19621 cttgccccgg acttgacata aacggtaaaa aaattttatg aaaagtagtt aaggagggac
    19681 agttatgaaa agttatatag ctaagccagc tgatgtacaa agaaaatggt acttagttga
    19741 tgctgaagga aaaacattag gtcgtttagc aacagaaatt gcgacagtat tgagaggtaa
    19801 acataaacca acatttactc ctcacgttga tggtggagat tttgttgttg tagtaaatgc
    19861 agaaaaaata gttttaagtg gtaagaaatt agatcaaaaa tattacagat accatactgg
    19921 ttatgtaggt ggattaaaag aaatatctta cagagatatg atggataaga aaccagaaga
    19981 agttatatca catgctgtaa gcggtatgtt acctaaaaat aaattaagaa gcagaatgat
    20041 gactagatta agagtatttg caggtgctga gcacactcat gcagctcaaa atccagaagt
    20101 tttaaacttt aaataagatt aataggtgaa aggaggagtt tataatggct aacgttcaat
    20161 attatggaac tggaagaaga aaaagttctg ttgctagagt aagactagtt gcaggtgaag
    20221 gaaatatatt agtaaatgga agagcattag aaaattattt taattatgag acattaataa
    20281 gagatgttaa acaaccatta gttttaactg gtaatgaaaa taaatatgat gttatagtaa
    20341 aagttgaagg tggaggattc actggacaag ctggagctat aagacatgga atatctagag
    20401 ctttattaaa agctgattta gatttaagac ctgctttaaa gaaagaaggt ttcttaacta
    20461 gagatgcaag aatgaaggaa agaaagaaat acggattaaa agcagcaaga agagctccac
    20521 aattctcaaa aagataatta cttatttttt tggaaaagca aaatccttta tttactgtta
    20581 ttcagaaagt attggtattt taaaaatgtt gggttaagtt aattattgat atataataaa
    20641 ataataagat atcttattag gatgtttttc attaagaaga acatcctttt tattttgact
    20701 atttaataaa aaac
//
LOCUS       DAMJWO010000077        19820 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.079, whole genome shotgun sequence.
ACCESSION   DAMJWO010000077 DAMJWO010000000
VERSION     DAMJWO010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19820
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.079"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            165..1316
                     /locus_tag="PC366_002890"
     CDS             165..1316
                     /locus_tag="PC366_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDF2578387.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     AIKEVRQDIAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKNAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRPSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDVVISKVNNLKNILKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSYV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
     gene            1362..2537
                     /gene="thiI"
                     /locus_tag="PC366_002891"
     CDS             1362..2537
                     /gene="thiI"
                     /locus_tag="PC366_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HDF2578388.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGRFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIEA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDRINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEEATILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSIVPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            2693..3496
                     /locus_tag="PC366_002892"
     CDS             2693..3496
                     /locus_tag="PC366_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2578389.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEESSKDKNEVIKEVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGIESIAKVYVTCTKHPDGIEMARDIHQSMKDLIASFAQDPSIIPGASKGNDDFRKY
                     LLDNKYKNGWPTIPDEFKAKYGLSKDTLYIQPYAYNPTKSDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            3739..4380
                     /locus_tag="PC366_002893"
     CDS             3739..4380
                     /locus_tag="PC366_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HDF2578390.1"
                     /translation="MNNNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKEISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDIGILTGNITTAAQALGLGSCIIGMVRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYRELLDIPEGYSVPFGIAVGIPDGNLPNAREVVYKVSRV"
     gene            5793..7463
                     /locus_tag="PC366_002894"
     CDS             5793..7463
                     /locus_tag="PC366_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF and EAL domain-containing protein"
                     /protein_id="HDF2578391.1"
                     /translation="MREESNSLSLDHIEIFFELLSQSTEDYIFFWDINRNKFKISSAI
                     FDEFNLSKEIESDLVNCWSKIVYPDDVQIWKDDIQELLHGKKGEHNLEYRLINKYEEI
                     VWISCRGKVYVSDDPKTIFLVGRIKNIGEKNKFDSITGTWNREQFEHRMNYLIKEKIY
                     KNGAMFIMDIDNFKNINEKYGHSYGDKVLRAIATEVLEYLPKDVRLYRLDGDEFAFFY
                     PMCTKETIEKIYEKIQMYTNTQHEIESNKYYCTVTAGVAMYPEDGDNYLDLFKHADIA
                     LDIAKISGKNRIKFFSQELYENKLKVISMQQKLRECVENNFNDFELFFQPQVNAVTKE
                     VIGAEVLLRWHSSTYGEVSPVEFIPILEQSNLIIPVGKWIIKEAVKQCKEWHKINPDF
                     KISVNVSYIQLKEDFFRDFIVECLVEYQLRPEFLILELTENCWIPDINLLNDKFISLK
                     GIGVYIAIDDFGTGYSSLNYLKELSVNIIKIERSFVKNITYNSYEYTFLEYIIKLAHI
                     INLKVCVEGIESYEEYDIVKSLGVDIIQGFLFGRPVSASEFYKFQLSK"
     gene            complement(7585..8319)
                     /gene="pflA"
                     /locus_tag="PC366_002895"
     CDS             complement(7585..8319)
                     /gene="pflA"
                     /locus_tag="PC366_002895"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HDF2578392.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSGGGITASGGESTLQPEFLSELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNTDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDIDNLEKLGQFVATLKNVERFELLPYHSMGIHKWESLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(8479..10710)
                     /gene="pflB"
                     /locus_tag="PC366_002896"
     CDS             complement(8479..10710)
                     /gene="pflB"
                     /locus_tag="PC366_002896"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDF2578393.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDEAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPAALGKDMTERINNLSAMMDGYFS
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
     gene            11003..12064
                     /locus_tag="PC366_002897"
     CDS             11003..12064
                     /locus_tag="PC366_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HDF2578394.1"
                     /translation="MEKRKSIHLHKLNIYLIGGGDRLFITVVLFLVGFLLITKGADIF
                     INCTVEIGRKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICN
                     TGLALGLVVFISPFNVDKKMFFSKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIF
                     YMVNNYRSVVGKSDTKNRNIKNNTIKDISTKKGKNYRGFSVLEIVKILLLFATGLIMM
                     IIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNI
                     LGANILNIVSVIAVSAIPNNIPILSQNRQLDIPFMILLLLIVIIPTLKSNRLSRIQGI
                     LMLFTYFLYISILYFMYII"
     gene            12155..13768
                     /locus_tag="PC366_002898"
     CDS             12155..13768
                     /locus_tag="PC366_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2578395.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLEGFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            14043..16028
                     /locus_tag="PC366_002899"
     CDS             14043..16028
                     /locus_tag="PC366_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDF2578396.1"
                     /translation="MSMTYMDPRVFLILEMVLEEDTNTLEQFSNVLGVSTRTIRNYIN
                     QINRELKGGIAKIVKNEKGTYSIRIEDESKLIEIVNFNRGKLSNFINLNSPDERINYV
                     LDILTMTNNPITIDDLAEEICIGRTTLIKDLKKADRILAEYDLELKRKPNIGMILVGE
                     EMDIRLLILDRLYENYIDVLENVNQINLVKDYDIECLRDELKKLFKKEELYITEQVLR
                     DVERYIIMSVLRNLNGYKFEKIDKRFEVIRCSDEYTLGLKLKALLEKIFNIVLNEKET
                     IFLTMPLIGRKAPSTKLALSSIKINDSVKEVVDEVTSFLLETSGIDFKEDKKLIENLE
                     YHLYFALNRMRFNIRVKNPLLQEIKERYTFPYSVAKIAAMIIEEKFDLKICDHEIGYI
                     ALHFGSYFEKNSRKVLNVNRVAVVCGTGLGTAQLIRIKIGKILGESVEVNTFSDIEAK
                     ANLDLLKYYDLVFTTVDFKTDLDVPIFRVNALFNEESIKKEIENAILLKNSINLKSIK
                     KIEKNIPFIGKLIEEDKFFILNKSTFMENLEDMLEKLVHKGIIDIEFKKKVLKREKKS
                     STALDNYIALPHSVNTNGENLYLSFGILEKPVVWDTKEIRIIILMIIPDKNVDSTDLI
                     IKSYEEVLEVGRDKKMIEELAKVKSFDEFYKIITKRR"
     gene            16033..16467
                     /locus_tag="PC366_002900"
     CDS             16033..16467
                     /locus_tag="PC366_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HDF2578397.1"
                     /translation="MDPVIFIIASLITVYLLNIFLGYLQLKDFNKNYIELKRKGRVAI
                     GRKKGRISSGTIVLILINDDGVIVETRKMQGVTVLARVKSFEGLVGKSLEYIEKSDLT
                     VYNKLLKKAILDAVKQYITFEKNKCEDTNNLSTDEECRMEVV"
     gene            16496..17056
                     /gene="srlA"
                     /locus_tag="PC366_002901"
     CDS             16496..17056
                     /gene="srlA"
                     /locus_tag="PC366_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418408.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDF2578398.1"
                     /translation="MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTM
                     NAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTFVFANPMTLSLGRFLPEKFKPSY
                     FAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIK
                     GVVTDYTTKFVEKQQGIALNSDIKIG"
     gene            17120..17488
                     /locus_tag="PC366_002902"
     CDS             17120..17488
                     /locus_tag="PC366_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbose transporter subunit IIB"
                     /protein_id="HDF2578399.1"
                     /translation="MAFNKVKIVKGSGGWGGPLIIEPTEKKNKVVYVTGGAKPETAVK
                     IAELTGCELIDGFSQGVKDDEIACVIINCGGTLRCGIYPQKKIPTINIMKTGKSGPLA
                     MFIKEDIYVSGVKPTNVEQL"
     gene            17513..18079
                     /locus_tag="PC366_002903"
     CDS             17513..18079
                     /locus_tag="PC366_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDF2578400.1"
                     /translation="MAYDTKKKISEQSQGIVAKIGIALGNVTSTLFQAGRDTIDTLIH
                     TILPFMAFVAVLIGIINQSGIGNWVANLLTPLIGNVGGLVVLSIICSFPLLSPFLGPG
                     AVIAQIVGVLVGTEIGKGNIPPSLALPALFAINSQAACDFIPVGLGLAEAEPDTVQVG
                     VPSVLYSRFLTGAPTVLLAWLASFGLYK"
     gene            18120..18485
                     /locus_tag="PC366_002904"
     CDS             18120..18485
                     /locus_tag="PC366_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDF2578401.1"
                     /translation="MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHS
                     ENNLVKEILTNDVLSINNVDYKITSVGELVNQNLSELGHITFKFTGEKDGAIGGTLYL
                     EEKEIAPIGVGTILKIIRK"
     gene            18586..19359
                     /gene="srlD"
                     /locus_tag="PC366_002905"
     CDS             18586..19359
                     /gene="srlD"
                     /locus_tag="PC366_002905"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HDF2578402.1"
                     /translation="MRKVALVVGGGRSLGEYLSKHLAKVGYDVAIADLNEDNAKKVAE
                     EIETEFGCKSVGYGCNAIDERQVISTVKAIENDFDRIDLLVYNAGVAVSKKITDFGYK
                     DFKFIVDVNLNGYFLFAREVSKVMIAKGIEGRIIQINSKSGRVGSKHNSGYSAGKFAG
                     VGLTQSLALDLAEHKITVNALMLGNLLDSDMFESLIPQYAVKLGIPESEVKQVYIDKV
                     PLKRGCRFIDVANMLTFYASKEAEYCTGQSINITGGQVM"
BASE COUNT         7704 a         2222 c         3434 g         6460 t
ORIGIN      
        1 ttttactata aaaatttgta ataaagtgaa aaaactagct tttcatgaaa taatatttta
       61 taatttaaga ttgtcttttt aataaagatt aacaaaaaaa atactataat tagtggtata
      121 atagttagag ttgaagattt taaataaagg taggtgtaat taagttggaa atatacttag
      181 acaatagcgc aactacaaaa ccttatcaag aagttataga taaaatggtt tatgcactta
      241 atacggaata tggaaatcct tcttctgtcc atagaaaagg tgtagaagtt gaaaaagcta
      301 taaaagaagt aagacaagat atagctaaat ctctaggagc gaaagaaaag gagatttatt
      361 ttacatcagg tggtacagag tgtaataata ctataataag aggtattact agtttaaata
      421 aaaaaagaaa aaatcacata atatctacta acatagaaca tccttctgtt ttaaatacat
      481 taaaagattt agaagaagat ggttttgaag taacttattt agaggtcgga aaagatggga
      541 aaataaatat agaggattta aaaaatgcga taaagtcaac tacatgctta gtaagcatga
      601 tgcatgttaa caatgaaata ggaactatac agccaatagg tgaagttgga aagtatttga
      661 agggtttaaa agaaaaaatt tatttccatg ttgatgctat tcagtcatat ggaaaaatta
      721 attttagacc atctaaatac aatatagatt ttatgagtgt aagtgcacat aaatttcatg
      781 gtccaaaggg aattggattt atgtatataa aagaaaataa tcgccttaag cctatgttaa
      841 caggtggtgg tcaggaaatt ggaattaggt cgggaacaga aaatgtacct ggaatatatg
      901 gtcttggaga agctgttaga atactaaaca aagatttaga tgttgttatt tcgaaagtaa
      961 ataacttaaa aaatatatta aaaaatgaaa taattgataa tatagaagat ataaaaatca
     1021 attctccaga agatggagta tgtcatatat taaatgtatc atttagaggg acaaaaggag
     1081 aagttttact tcattaccta gagcaaaaag gtatttatgt atcaactggc tctgcatgtt
     1141 cttctaaaaa gaaaggtagt tacgtattaa atgctatagg tcttacaaat gaagaaataa
     1201 atggaacaat aagatttagt ttatctgata tgaatacaga agaagaaatg ttagaagctg
     1261 tgaaagtttt gaaagaatca atttgtgact taaggtcaat aatgaaaaga aaataaagaa
     1321 tactgtatag atagtgataa taaattagtt taagaggtga aatggtgtat aatatattaa
     1381 tagtaaagta tggagaaatt ggagtaaaag gaaagaatag atatatattt gagaataggc
     1441 ttataagaaa tataagaaat atgttaaaac caattggaag atttaatgta tataaagagt
     1501 atggaagaat atatgttgat ttagaagact atgattatga agaagtaatt gaagaagtta
     1561 gaaaagtatt tgggatagtg ggtgtgtgcc ctggagtaag agctaaaaaa gattatgata
     1621 cattaaaaga aatagcttta aaaatgttag aagaaaaaat agaggctgga tataaaactt
     1681 ttaaggtaga gtcaagaaga ggagataagt ctttcgggtt gacttctcaa gaaatgagta
     1741 tggatatagg tggatactta ttatcaaagg taggagatag gattaatgtt gatgtaagaa
     1801 atccagaagt taaaataaag tgcgaataca gagaatttca tactatggtc tatagtgata
     1861 ctatacctgg atatggtgga ttgccacttg gaacgaatgg tagagctatg tctcttttat
     1921 caggaggtat agatagtcca gtagctacat ggatggttgc aaaaagaggt atggaggtag
     1981 aggcagttca cttccatagt tatccattta caagtgaaag gtcacaggaa aaagttaagg
     2041 atttagctaa aatactggca aaatactgtg gtagagtaag acttcataaa gttaacatat
     2101 tagaaataca aaaagcaatt ggtgagaatt gtaatgaaga agaagctact attctttcaa
     2161 gaagatttat gatgaggata gcacagagac tttctgaaaa aagacattgt gatgctttaa
     2221 ttacaggtga aagtattggg caggttgcat ctcaaactat acaagggctt acttgtacta
     2281 atgccgttgt agacttacca gtgtttagac cacttatagc aatggataaa tcagatatag
     2341 ttgatatagc caaaaaaata gggacttttg aaacatctat agtgcctgaa gaagattgtt
     2401 gtagtgtatt ttctcctaga aagcctgtca ctaaacctag attagagaaa atagaaaaat
     2461 ctgaaacagc acttgatatt gaaaaattag tacaggatgc tattgacaaa atagaggtag
     2521 aggatattga gttttagcat acaagttatt taattactaa attgaatatt gagtatatta
     2581 gtagttctgt aagtatatta gtagttctgt tgaaaggatt tatgtagaca atttattaat
     2641 atatagtatt taaaaataag tactataatt ttatttaatg ggaatgatta ttatgaataa
     2701 aaagggtttt acattaattg aattgttggt agttatatct ataataggaa ttttagttat
     2761 agtagctgtt ccagcgttat ttagaaatat agaaaaaagt aaggcagtta catgtctttc
     2821 taatagagaa aatataaaga ctcaaattgt tattgcaatg gctgaggaat caagtaaaga
     2881 caagaatgaa gtcataaaag aggtattaga aaacaaagat ggtaagtact ttgaaacaga
     2941 accaaagtgt aagtcaggtg gaatatattc agcaacgttt gatgatggtt atgatggaat
     3001 aactggaata gaaagcattg caaaagtgta tgttacttgt acaaaacatc cagatggtat
     3061 tgaaatggct agggatatac atcaaagtat gaaagatttg attgcatcat ttgcacaaga
     3121 cccttctata ataccaggag cttcaaaggg caatgatgat tttagaaaat atttattaga
     3181 caataaatat aaaaatgggt ggcctacaat tccagatgaa tttaaggcaa aatatggatt
     3241 aagtaaggat acactatata tacaaccata tgcatataat cctactaaat ctgatgctac
     3301 tgtagttgta tttgcaaata ataagactgg aggtaattgg tatacttccc tagtttacga
     3361 ttatgatgaa ggtagatggt ataaaggtaa aaatggtatt tctgttgcag gtaggtcatg
     3421 ggatgttgac acagatagtg ttaagtctgt aaaaacagag attcattcta aagagggatg
     3481 gggtccttta aattaatata tcatgtttta ttaatctggt attgattaaa ctatagaaaa
     3541 gagcagtttc tatagatgac gaataccaga ttttcattta tatgtataat taagatatat
     3601 taaaagtatt tatattttta agtcttcaca tacaagctaa agataattat aataatattg
     3661 taaagaaatt taattataag attaattttc tgaagattta gtatttgtac taagaaatac
     3721 ataaaaaggg gaatagatat gaataataat tttcaagaca accaaacaat aaatttaata
     3781 caaagtcgta gaagtatacg aaaatttaca acagagcaaa ttagtgatga gcaagtaaac
     3841 acattattac actgtgcatt tgcagcacct tcaggatgta ataaacagcc ttggcacata
     3901 actgttgtgc aagaccagaa acttttaaaa gagattagtg atgatacttt atctaggatt
     3961 catgaagtga gtaatgttga gataaataaa aactttaagt tattttatgg tgctccaacc
     4021 gttttattta tttcttatga tgaaagtagt tcatgggctc catatgatat aggaatactt
     4081 acagggaata taacaacagc tgcacaagca ctagggcttg gaagttgtat aataggaatg
     4141 gttagaggtt tatttacacc tgttgaacaa ggggatattg aaggtcttgt gagtgtattg
     4201 gataaagaag atgtaaagga atcagagtca ataaagatga agtttgatac aaataaaaaa
     4261 tacagagaac tacttgatat accagaaggg tattctgtac catttggtat tgctgtaggt
     4321 attccagatg gaaatttacc aaatgctaga gaggtagttt acaaagtttc cagagtttag
     4381 gataaagtat tgcaagaacc aatcagttac ttgaagaatt aaaccagtaa tatacaaata
     4441 aattgatgga agaggaagct atttaaaaag tagtttagat ttttcattgt aaaataatta
     4501 aataaagaat aaggtgataa gtattttatt tattatctta ttctttttta tttttgtttt
     4561 gtagaatgat aaaaataagg attaagtgta ataaaataga aaacaagtat gttaatttta
     4621 agtatatgct ttaaaattta tccaagttaa aaatttaaga tatcttttca gtataatgga
     4681 aaaaatgtca aaatattgaa atagggaaaa aatagtgata taataaaaaa aatagagaaa
     4741 aaaagtaacc cttagttgta aaaaagttac tatttattga aaatttagat acttttctaa
     4801 aaattatcta tgttaatagt taaatttatg aacatttttt gtttttatgt taggatattt
     4861 cttagaaatg aaatacttct taatttgatt tgatatgtat atttttatag ctattttatt
     4921 ataaaaaaaa agaacccttt tacaacaaat ggaaactatg tacgtaataa ttaaaataaa
     4981 aaatattatt ttatatttat aaacattgac attctaattc tgtagtgtaa tcgtattttt
     5041 tattaattct tataaaatca atgaaaataa ggatatccat tttaaagtac ataaatttaa
     5101 aaatccagaa aaatatactt aaattatgta agcaaaagag gggttgaatc ggctgaaaat
     5161 gtaatactag taaatagtac atcaatccta gataccctgt aagcaactct attttcatgt
     5221 actaaaaatg tacctatttt attaactgaa aagaataaat taaatgtaag tacataataa
     5281 gagataaaaa attaaaagca aaaaatattt atataaataa atataaaaaa tgatataatc
     5341 cctattaaaa aatttataga tgatgaagaa atatcaaaat cttatattat aggaagaggc
     5401 acttctttgc caaaatatat agaaaagcaa taccaaatcc aaagagaata ggctgagaaa
     5461 aaataaaaca aattcaagag taatagaaaa gctttataga ataaagaact gagaactctt
     5521 tatataataa aaaatggact tttaagagaa aatgatttaa taaatgattt aacatggtgt
     5581 tttagcaggt gaaaataaat caccagtaat gattgtagaa aaattacttt atgaatctca
     5641 aaaaaactta gttaagagta agagatttga taagataact aaagttgggg aaatgtgttt
     5701 gatgagataa aaaaattagt aaaatagtat aatctaaata agaatatttt gttgattaaa
     5761 ctacactaat agtaatattg tagggggaaa agatgagaga agaatcgaac tctttaagtt
     5821 tagaccatat agaaattttc tttgaacttt tatctcaaag tacagaagat tatatatttt
     5881 tttgggatat aaataggaat aaatttaaaa tttcttcagc aatttttgat gaatttaact
     5941 taagtaaaga gatagaatct gatttagtca attgttggag taaaattgtt tatccggatg
     6001 atgttcaaat atggaaagat gatatacaag aattactaca tggaaaaaaa ggtgagcaca
     6061 atttagaata taggttgatt aataaatatg aagaaatagt atggatttct tgtagaggta
     6121 aagtttatgt gtcggatgac ccaaaaacta tatttctagt cgggagaata aagaatattg
     6181 gtgaaaaaaa taaatttgat tctatcacag gaacgtggaa tagagaacaa tttgaacata
     6241 gaatgaatta tcttataaaa gagaaaattt ataaaaatgg tgctatgttt atcatggata
     6301 ttgataattt taaaaatata aatgaaaaat atggacattc ttatggtgac aaagtattgc
     6361 gtgcaattgc tactgaagta ttagaatatc ttccaaaaga tgtaagattg tataggttag
     6421 atggagatga atttgcattt ttttacccta tgtgtactaa agaaactata gagaaaatat
     6481 atgaaaagat acagatgtat acaaatactc agcatgaaat tgaatcaaat aagtactatt
     6541 gcacagtgac tgcaggagtt gctatgtatc cagaagatgg agataattat ttagatttat
     6601 ttaaacatgc tgatattgca ttggatatag caaaaattag tggtaaaaat agaattaagt
     6661 ttttttcaca agagctctat gaaaataaac taaaggtaat ttcaatgcaa caaaaactaa
     6721 gagagtgcgt tgaaaataat tttaatgact ttgagctgtt ttttcaaccc caggtaaatg
     6781 ctgttacaaa agaggtaata ggggcagagg tacttttaag atggcattcg agtacttatg
     6841 gagaagtatc tcctgttgaa tttataccaa tactagaaca gagtaattta attataccag
     6901 ttgggaagtg gattataaaa gaagctgtaa aacagtgtaa agaatggcat aaaataaatc
     6961 cagactttaa aatatctgta aatgtatcgt atattcagtt aaaagaagat ttttttagag
     7021 attttatagt agaatgttta gtagagtatc aattaagacc tgaattttta attttggaat
     7081 taacagagaa ttgttggata ccagatataa atttactaaa tgataaattt attagtttaa
     7141 agggtatagg agtatatatt gcaatagatg actttggtac agggtattca tctttaaatt
     7201 accttaaaga actgtctgtt aatataataa aaattgaaag aagttttgtt aagaatatta
     7261 catataatag ttatgaatat acttttcttg aatatattat taaattagct catattataa
     7321 atttaaaagt ttgtgttgag ggaatagagt cttatgaaga gtatgatata gtaaaaagct
     7381 taggtgtaga tattattcag ggttttttat ttggaagacc tgtaagtgcc tctgaatttt
     7441 ataaatttca actatcaaag tgatgtacat aaaatgagat atatagtata taaaaatagg
     7501 gcaaagtgga agttttgaag tttattaaaa atttacactt taccctattt tgttatgtct
     7561 tctataaagg attaatatac tacactaact attatatact ttcactccaa atttagagat
     7621 tatttcacta gctttttgga catcttcctt agtggcatca ggaacatctt ttagttcata
     7681 atcgatacct aaactttccc atttgtgtat tcccatagaa tggtatggta gcaattcaaa
     7741 tctttctaca tttttcaatg tagctacaaa ttgacctagt ttttctaaat tatctatatc
     7801 atcagtaatg ccaggaacta aaacatgtct tatccataca ggaatatttc ttgattctaa
     7861 gtgtctagca agttttaatg ccttatccat accaacacca gtcaaatcaa tagatttttc
     7921 ctcaaccata tgttttaaat caagtaaaac caaatcagta ttatctaaaa ctgggtctat
     7981 agtttctata tctacgaatc cagatgtatc caagcaagtg tgtatatcat tttcttttgc
     8041 ttttttaaat aattcactta aaaattctgg ttgaagagtg gattcaccac cagaggcagt
     8101 tatacctcca ccagaaaact tcataaaaga agtatactta agagcatccg ttattatttc
     8161 atcaactgtg tattcttttc ctgatttaat atcccatgta tccctgttat gacagtattt
     8221 gcatctaaga ggacacccct gaaaaaataa tatatatctt attcctggtc catctacagt
     8281 accaaacgtt tctatagaat gtatctttcc cttaatcata gagttcacct cacaatatat
     8341 tttaataacc ttatcaatag ttataatatt tgtctaaaaa aggccatctt ataccagaaa
     8401 taattcaaat ataagatagc cttttatttt tattttttac acagtagtaa tcttagttaa
     8461 agtataaaaa tttaaagact aagccatttt accgtggaat gttctgttta taacatctaa
     8521 ttgttgctct ttagttaatt ttatgaagtt aactgcatat ccagatactc ttatagttaa
     8581 ttgtggatat tcttctggat gttccatagc atcttctaaa gtagctctat caaatacatt
     8641 tacatttaag tgatgagcat tttgagagaa gtatccatcc atcattgcag aaagattgtt
     8701 tattctttca gtcatatctt ttcctaaagc agcaggtact atagagaaag tattagatat
     8761 accatcttga gcatgttcat atggtaattt agcaactgaa gataatgaag ctaaagcacc
     8821 attagtatct ctaccatgca ttgggttagc accaggagca aatggagcac cagctcttct
     8881 accatctggt gtattaccag ttttcttacc ataaacaaca tttgaagtta ttgtaagtat
     8941 agattgagtt ggataagaat ttctataagt tttatttttt cttattttat tcataaagct
     9001 ttcaactaac tctacagcta tactatcaac tctatcatca ttgtttccgt attttggata
     9061 atctccttct atttcaaaat caacagctat tccttgttca tttctaatag ttttaacctt
     9121 agcatgtttt atagcagata atgagtctgc acaaactgat aacccagcca taccacaagc
     9181 catagttcta aatatatctc tatcatgtaa tgccatttct aatgcttcat aagaatattt
     9241 atcatgcata taatgtatta catttaaagt atttacatat aatgttgcta accaatcagt
     9301 gaatggttca aatttactca taacttcatc ataatctaag tactcagaag ttataggttc
     9361 aaatcttggt ccaacttgaa caccagattt ctcatctaca ccaccattta tagcgtataa
     9421 taaagtttta gctaagttaa ctctagctcc aaagaactgc atttgtttac caattctcat
     9481 tgcagataca caacaagcta taccatagtc atctccccag tatgctctca ttaaatcatc
     9541 attttcatac tgtactgaac ttgtatctat agatacttta gaacagaaat ctttgaatcc
     9601 ttgaggtaat ttagttgacc atagaactgt taagtttggc tctggagaag gtcctaatgt
     9661 atatagagta tttaacattc taaatgagtt tttagtaact aatgttctac catctattcc
     9721 catacctcct atacactcag ttacccaagt tgggtctcca gagaataggt tattgtaatc
     9781 aggagttctt aggaacttaa ccattcttaa tttcataaca aaatggtcca tatactcttg
     9841 taattcttct tctgttacga ttccagcttt taaatctctt tcaaagtata tatctaagaa
     9901 agtagatgtt ctacctaaag acattgcagc accattttgg tctttaacag cacctaaata
     9961 accaaagtat aaccattgta cagcttcttt tgagttagtt gctggttttg atatatcaaa
    10021 tccataagat tcagccattt ttttaagttc atttaaagct gatatttgct cagttatttc
    10081 ttctcttaat ctgataactt cctcatccat gcaagaaact tctaatgatt tcttttgctc
    10141 atttttatct tctattaaag catcaacacc gtatagagca actcttctgt agtcaccaat
    10201 tattctacct ctaccataag catctggaag acctgttatt ataccagatt ttctagcagc
    10261 tctcatttct ggagtataaa catcaaaaac tccttggttg tgtgtttttc tgtatttagt
    10321 aaatatatct tttatttctg ggtctaattc atatccaaaa gcttcgcatg aattttcaac
    10381 catctttata ccaccatatg gcatgacagc tctttttaaa ggggcatccg tttgtaaccc
    10441 aactattgtt tctaattctt tatctaaata tcctggagca tatgcagcta ttccagaaac
    10501 agtttttgta tcaacatcta aagtaccacc attttctctt tcttttttaa ataggaccat
    10561 tgcttcgtcc cataattttt tagtattttc agtggcacca gctaagaaag agtcatttcc
    10621 ctcatatgga gaatagttta attgtataaa ctctctaaca tttatttctt tagtccatct
    10681 tcctgtttta aatccttgcc atgcattcat taagtatttc ctccttagat ttaaatgata
    10741 aataatacta ttaaaattat tttttatata cttaatttat tttatatatt tttttaaaaa
    10801 tatattttct aatataataa tatcatatta ttcgtatcct gtatacataa aaaataaaaa
    10861 attgtcgctt taaagtataa aacagattat atgttaataa tgtggtgaaa ttatacccat
    10921 atataaataa aataaaacaa ataaatagct aattaaggag aaaatatttt ttattttttg
    10981 tttaggataa ataaatttta ttatggaaaa aagaaaaagc atacatcttc acaaattgaa
    11041 tatttattta atagggggag gtgatagatt gtttatcaca gtggtattat ttttagtagg
    11101 tttcctatta attactaaag gcgcagatat ctttataaat tgcactgtag agataggtag
    11161 aaaaacgaat atatcagaaa ttatacttgg agctactata gttagttttg caacaacatt
    11221 acctgaattt acagtgtctc tacttgcttc tattgatggt catactacta tgagtttagg
    11281 aaatgcagtt ggttctataa tatgtaatac aggattagca ttagggttgg ttgtttttat
    11341 aagtccattt aatgtagata aaaaaatgtt tttttctaag tctttactat taatagtatc
    11401 cgttatagtt ttaattttat tgagtttaga tggagttata acaagaggtg attcattatt
    11461 acttataata atattaatct tttatatggt taataattat agaagtgtcg ttggaaaatc
    11521 tgatactaaa aatagaaata ttaaaaataa cactattaaa gacatatcta ctaaaaaagg
    11581 gaaaaattat agaggttttt ccgtattaga aattgtaaaa atactattac tttttgctac
    11641 aggattgata atgatgataa taggttcaca aatccttata gagagtggag taataatagc
    11701 tagtttttta aatatacctc agggtatagt aagtttaact ataatagcac ttggaacttc
    11761 tctgccagag atagtttcgt cgattactgc tataagaaaa aatcatcatg aaatatcagt
    11821 aggaaatatt ttgggtgcaa acatattgaa tatagtatca gtaatagctg tatcagcaat
    11881 accaaataac ataccaatac tatctcaaaa tagacaattg gatataccat tcatgatatt
    11941 attattatta atagtaataa taccaacact taaatctaat agacttagta gaatacaagg
    12001 tatattgatg ttattcacat attttctgta catatcaatt ttgtatttca tgtatattat
    12061 ttaactatac tgtttaaaat attaattgca gaatatccta aaaaagtata taatggatag
    12121 gttaagatta attgataacg gagaggaata atatatgaat ataacaaagt ttgaagattt
    12181 accaataagt gagggaataa aaaaagctat agctgaaatg gggtttgaag aaccatctcc
    12241 tatacaagca cagtctatac ctgcgatttt gtcaggtaaa gacgttatag gacaagctca
    12301 aactggtacg ggaaaaacag ctgcttttag tatccctata ctagaaacaa tagacccaaa
    12361 taatagaagt ttacaagctg tagtgctttg tccaacaaga gaactggcaa tacaagtatc
    12421 aacagaaata agaaagttag ctaagtattc gcacggaata aagacattac ctatatatgg
    12481 tggccagcca atagatagac aaataaaatc tctaaagagt ggtgtgcaag ttgtaatagg
    12541 tacaccagga cgtacaatag accatatcaa tcgtaaaaca ttaaagatgg ataatgtaaa
    12601 aatgattata ttagatgaag cagatgaaat gctagatatg ggatttagag aagatataga
    12661 aatgatttta agtaagattc cagaagaaag acaaacaact ttcttttcag ctactatgcc
    12721 aagaggaatt ttggaattaa ctaagagata tcaaaaagac ccagagcata taaaagttgt
    12781 tagaaaagaa cttacagttt caaatacaaa gcaatactat atagaaacta ggtcatcaaa
    12841 taaattagaa gtattatgta gattagtaga tgtatatgac cctaaactat ctgttgtttt
    12901 ctgtaatact aagagaaaag cagatgaatt ggtaggagat ttacaagcaa gaggatattt
    12961 tgcagatgca ttacatggtg acttaaaaca gactcaaaga gatatagtaa tggataagtt
    13021 tagaaatggt acaatagata tacttgttgc tactgatgtt gcagctagag gtatagatgt
    13081 tgatgatgtt gaatgtgtat tcaactatga cttaccacaa gatgaagagt attacgttca
    13141 tagaattggt agaactggtc gtgctggtag agaaggtatg tcatttactt ttgtatttgg
    13201 aaaagaaatg agaaagatga aagatataga aagatatact aaatctaaac taataaagca
    13261 taatatacca acaataactg atgttgaaga gaaaaaagta ggtactttct ttgcacaagt
    13321 taaacaaact atagaagaag gtcacttaac taaacaatta caatggttag aaggtttctg
    13381 taatgatgaa gattatgcaa tggttgatat agctgctgca cttgtaaaac tatctctagg
    13441 tgaagaaatg aaagaagaaa taatagaaga aaaacctaga agagagcgtg gagatagaaa
    13501 aggtggtact ggagctaaag atggtatgat tagattattt atcaatattg gtagaaatca
    13561 aagagtacaa gcaaaagata tagttggtgc tatagctgga gaagttggaa taccaggtaa
    13621 agtagtaggt actatagata tatatgataa gtatactttt gttgaaatac ctaaaaaaga
    13681 tgcaaaaaca gtaattgaaa agatgaaaga tattaagata aaaggtaata agattaatat
    13741 agaaaaagca aataagaaga aaaaataacg tatagtatac aaaactataa ttagaaaata
    13801 tataaaataa tatattggat atttaaaaag cctgatgtgt tttcaaaaca gatagtagat
    13861 aatctgtaag agttaacagc ataaggcttt tcttgtttta tatgatatta tgattttcca
    13921 gatcgttgtg aaaaatgtat attagttcct ttttttcaaa tctgatttga aaaagagaat
    13981 attaattatc tatatagttt agattataat aaaaaatgta agataacaaa ggggagaaaa
    14041 agatgtcaat gacttatatg gaccctaggg tttttttgat tttagaaatg gtgttagaag
    14101 aagacacaaa tactctagaa caattttcaa atgttttggg tgttagtact aggactatca
    14161 gaaactatat aaaccagatt aatcgagaat taaaaggtgg tattgctaaa atagttaaaa
    14221 atgaaaaagg tacatatagt ataagaattg aggatgaaag taaattaatt gagattgtaa
    14281 attttaatag aggaaagcta tcaaatttta taaatttaaa ttcacctgat gaaagaataa
    14341 attatgttct tgatatttta actatgacca acaatccaat taccatagat gatttggctg
    14401 aagagatatg tataggaaga acaacattaa taaaggattt aaaaaaagca gacagaattt
    14461 tagctgaata tgatttagaa ttaaaaagga agccaaatat aggtatgatt ttagttggtg
    14521 aagaaatgga tataagatta ttaatccttg atagattgta tgaaaattat attgatgtct
    14581 tggaaaacgt taatcagata aatttagtta aagattatga tattgaatgt cttagagatg
    14641 aattaaaaaa gttgtttaaa aaagaagaac tctacataac agaacaggtc ttgagagatg
    14701 ttgaaagata tataatcatg tctgtcttaa gaaatctaaa tgggtacaaa tttgaaaaga
    14761 tagataagag atttgaagtg ataagatgtt cagatgaata tactttagga ttaaagctca
    14821 aagctttatt ggaaaagata tttaatatag ttttaaatga aaaagaaacc atatttttga
    14881 caatgccatt aataggtaga aaagctccta gtacaaaatt agcacttagc agtataaaga
    14941 taaatgatag cgtaaaggaa gttgtagatg aagtaactag ttttttatta gagacctcag
    15001 ggattgattt taaagaagat aaaaagctta tagaaaattt ggaatatcac ttgtattttg
    15061 cacttaatag aatgagattc aacataaggg taaaaaatcc tcttttacaa gaaataaagg
    15121 aaagatatac atttccatat agtgttgcaa agatagctgc aatgataatt gaggaaaagt
    15181 ttgacttgaa aatatgtgac cacgaaatag gatatatagc attacatttt ggaagttatt
    15241 ttgaaaaaaa ttcaagaaaa gttctaaatg taaatagggt agctgttgtt tgtggaacag
    15301 gtcttgggac tgcacaactt attagaataa agataggaaa aatacttgga gaaagtgtag
    15361 aagtaaatac tttttctgat atagaagcta aagctaattt agatttatta aagtattatg
    15421 atttagtatt tacaacagta gatttcaaaa cagacttaga tgttccaatt tttagagtaa
    15481 atgcgttatt taatgaagaa agtataaaga aagagataga aaatgcaata cttttgaaaa
    15541 atagtataaa tcttaagtct ataaaaaaga ttgaaaaaaa tatccctttt ataggtaaat
    15601 taattgaaga ggataagttc tttatattga ataagagtac gtttatggaa aatttagaag
    15661 atatgttaga aaaattagtt cataaaggaa ttattgatat agagttcaaa aaaaaggtat
    15721 taaaaagaga aaagaaatct tcaacagcat tagataatta tatagcattg cctcactcag
    15781 ttaatactaa tggggaaaat ctttatctgt catttggaat attagaaaaa ccagtggttt
    15841 gggatacaaa ggaaattaga ataataatat tgatgataat tccagataag aatgtagata
    15901 gtacagacct gataataaaa agttatgaag aagtacttga agtagggaga gataaaaaaa
    15961 tgatagaaga acttgctaaa gtaaaatcat ttgatgaatt ttataaaata attaccaaga
    16021 ggaggtaata atatggaccc agtaattttt attatagcat cacttattac agtgtattta
    16081 ttaaatattt ttcttggata cttacagctt aaagatttta ataaaaatta tattgaacta
    16141 aaaagaaaag gaagagtggc aataggcaga aaaaaaggaa gaatttcatc aggtacaatt
    16201 gtgttgatac ttataaatga tgatggtgtg attgtcgaaa ctagaaaaat gcaaggtgtt
    16261 acagtattgg caagagtaaa gtcatttgaa ggtttggtag gaaagagctt agagtacata
    16321 gaaaaatcag atttaactgt ttacaataaa ctacttaaaa aagcaatact agatgcagtc
    16381 aaacagtaca taacatttga gaaaaataaa tgtgaagata caaataatct gagtactgat
    16441 gaagagtgta ggatggaagt agtttaaaaa aatatattta taaggaggag ttaatatgac
    16501 gcaatttttt caagtattag caagtggtgc agatagtttt atgaatttat ttagggcagg
    16561 tgggcaacaa tttgtaggtt ttgtaacaga tatagtacca cttttagtag cattattagt
    16621 tacaatgaat gcaattatca actttattgg tacagataga gtcgagagac ttgcaaaaaa
    16681 atgttctgca aatatattta ctagatattt gatattacca gtccttggta catttgtatt
    16741 tgcaaaccca atgacactat cactaggaag attcttgcca gaaaagttta aacctagtta
    16801 ctttgcagca gcaagctttt catgccatac aatgaatgga ttattcccac atatcaatcc
    16861 aggtgaacta tttatatatc taggaattgc aaatggtata acaactttgg gattctcaac
    16921 agcagattta gcagttagat atttgttagt gggtatagtt gcaaacttta ttaaaggtgt
    16981 agttactgac tatacaacaa aatttgtaga gaaacaacaa ggaatagcat taaattcaga
    17041 tataaagatt ggataattac tttaaggtat aaataaattt ttcaaataaa aagatagtgt
    17101 atagaggagg ataaattata tggcatttaa caaagttaaa atagtaaaag gttctggagg
    17161 atggggtgga ccattgataa tagaaccaac agaaaagaag aataaggtag tatatgtgac
    17221 tgggggagca aagccagaaa ctgcagtaaa aatagctgaa cttacaggat gtgagttaat
    17281 agatggattt tcacagggtg ttaaagatga tgaaatcgca tgtgtaataa taaattgtgg
    17341 tggaacattg agatgtggta tatatcctca aaagaaaata ccgactataa atataatgaa
    17401 aacaggaaaa agtggaccat tagcaatgtt tataaaagaa gatatatatg tttcaggggt
    17461 aaaaccaaca aatgtagagc agttataatt gaggtagtag gagggaagaa atatggctta
    17521 tgatactaaa aagaagataa gtgagcagag tcaaggaatt gttgcaaaaa taggtatagc
    17581 actaggaaat gtgacaagta ctctttttca agctggtagg gatactatag atacattaat
    17641 acatactata ctgcctttta tggctttcgt tgcagtccta ataggtataa taaatcaatc
    17701 aggtatagga aattgggtag ccaatttact tactccatta atcggaaatg ttggaggttt
    17761 agttgtctta tcaataatat gttcatttcc gttgttgtct ccgtttcttg gaccaggagc
    17821 tgttatagct cagatagtgg gggtattggt tggtacagaa ataggaaaag gaaatattcc
    17881 accaagttta gcattaccag cattgtttgc aataaactca caagcagctt gtgactttat
    17941 accagtaggt cttggtcttg cagaagctga acctgataca gttcaagtag gagttccgtc
    18001 agttttatat tctagatttt taacaggtgc accaactgtt ctattagcat ggttagcaag
    18061 ctttgggtta tataaataga agaatacttt ataaataatt agagagaggt tcagttgata
    18121 tggaattaat atacagtact caaataaata aaataggaga taatgcaaat gaatttttac
    18181 aacataatat gtttgtaact ttcaaagata atgctcctca agagttagaa aattactgtt
    18241 atatacattc tgaaaataat ttagtaaaag aaatacttac gaatgatgtg ttatcaataa
    18301 ataatgttga ttacaaaatt acttctgttg gtgagttagt aaaccaaaat ctttcagaat
    18361 taggtcatat aacatttaag tttacaggtg aaaaagatgg agcaattgga gggaccttat
    18421 atcttgaaga aaaagaaata gcacctattg gcgtaggtac tatactaaaa ataattagaa
    18481 aataaaattt aaaacgaatc taatcatatt ataagtaaat tatagataaa agtcaattta
    18541 actaatcaag ttaactttta atgtgataaa aaaggggaaa tgaaaatgag aaaagtggct
    18601 ttagttgttg gaggaggaag aagtttaggt gaatatttat ctaaacattt agctaaagta
    18661 ggttatgatg ttgctattgc agatttaaat gaagacaacg caaaaaaagt agctgaagaa
    18721 atagaaactg aatttggttg taaatctgta ggatatggtt gtaatgccat agatgaaaga
    18781 caggttataa gcactgttaa agctattgaa aatgattttg atagaataga tttattagtg
    18841 tacaatgcag gagtggctgt aagtaaaaaa ataactgatt ttggatacaa agattttaaa
    18901 tttattgtag acgtaaattt aaatgggtac tttctatttg caagagaagt atctaaagtc
    18961 atgatagcaa aaggtattga gggtagaatc atacagataa attcaaaatc aggtagagtg
    19021 ggaagcaagc ataattcagg atattcagca ggtaaatttg ctggagtagg acttactcaa
    19081 agtttagcgc tagatttggc agaacataag ataactgtaa atgcactgat gctcggtaat
    19141 ttacttgatt ctgatatgtt tgaaagttta attcctcaat atgcagtaaa attgggaata
    19201 cctgaatcag aagtcaagca agtttatata gataaagtac ctttaaaaag agggtgtaga
    19261 tttatagatg ttgcaaatat gcttacattt tatgcttcaa aggaagctga atactgtact
    19321 ggtcaatcta taaatattac tggtggacaa gttatgtaag gtttttatgg agtgtctcaa
    19381 gatgaactct ttagttcatg aggcactttt tttgtataaa attaaatata ttttcatcat
    19441 ttaaacaatg aaaaagaggt ttatctttat tttgagatag cctcattttt gtaattaaga
    19501 aacatagtgt ttaagtaaac atataagatt gttagttttt taaaagagaa ttttttaata
    19561 atattatatt tatgaagtat ttttaaactt aatttgatta aaaaatagct acgcacactt
    19621 gtgactttag tcatgagtta gtagctaaat tagtcagcat atagggaaac ttatatgtag
    19681 agataggata gaacctatcc aatactactt gaattgctaa aaacccctaa agctaaccaa
    19741 actaaaacat aagggtgaaa taaacctaag tgtgaaagtt acgaaagtag aaaaaattgg
    19801 ttagatggta taaggttaaa
//
LOCUS       DAMJWO010000078        19797 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.080, whole genome shotgun sequence.
ACCESSION   DAMJWO010000078 DAMJWO010000000
VERSION     DAMJWO010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19797
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.080"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            129..1493
                     /locus_tag="PC366_002906"
     CDS             129..1493
                     /locus_tag="PC366_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HDF2578403.1"
                     /translation="MDIKELVKMQRKYYNTGKTRDISFRIEQLKKLKLVVSQNEEKIL
                     LALKKDLNKSNFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKVVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLAAGNCVILKPSEYSVSTSSVVKDIVENTFSKE
                     YVAVVQGSQEESEKLLLERFDYIFFTGSTNVGKIIMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDRKNELIEKIKYYTNKYFGDNPC
                     NNEQFPKIINQRHFNRILSLIDKDKIVYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKLLEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKVL
                     KKIM"
     gene            1632..2798
                     /locus_tag="PC366_002907"
     CDS             1632..2798
                     /locus_tag="PC366_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF2578404.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAIF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGLLLTYATATLIL
                     YLFMHFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIIGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVMFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVESKLDKKGLPTDTSDYM"
     gene            2915..3697
                     /locus_tag="PC366_002908"
     CDS             2915..3697
                     /locus_tag="PC366_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HDF2578405.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQSSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMAYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYAESLGVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(3816..4469)
                     /locus_tag="PC366_002909"
     CDS             complement(3816..4469)
                     /locus_tag="PC366_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2578406.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(4493..5857)
                     /locus_tag="PC366_002910"
     CDS             complement(4493..5857)
                     /locus_tag="PC366_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HDF2578407.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSVFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLAAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKGATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
     gene            6515..7945
                     /locus_tag="PC366_002911"
     CDS             6515..7945
                     /locus_tag="PC366_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2578408.1"
                     /translation="MSSQESKPKGNLISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAVAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIEDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            8048..9151
                     /locus_tag="PC366_002912"
     CDS             8048..9151
                     /locus_tag="PC366_002912"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HDF2578409.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAIEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMTYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENKKFVAVLKEILNIKGEPSIG"
     gene            9166..9402
                     /locus_tag="PC366_002913"
     CDS             9166..9402
                     /locus_tag="PC366_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2578410.1"
                     /translation="MKRGVDMNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAH
                     VEVDESKCILCGICYQVCPDNVFEIIKEKACQEA"
     gene            9419..10468
                     /gene="vorB"
                     /locus_tag="PC366_002914"
     CDS             9419..10468
                     /gene="vorB"
                     /locus_tag="PC366_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HDF2578411.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVMEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREGDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RITENEQQWEDYQVEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALASKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            10470..11210
                     /locus_tag="PC366_002915"
     CDS             10470..11210
                     /locus_tag="PC366_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HDF2578412.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSVNGRDIKTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWGV
                     SLEKSIKWMEEEIVPYYALGEFKQRDGE"
     gene            11213..11752
                     /locus_tag="PC366_002916"
     CDS             11213..11752
                     /locus_tag="PC366_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HDF2578413.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENVT
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLLEKELALKTMCDFFEEKGK
                     GKFNVQNEAAFMEGYNNAI"
     gene            11876..13975
                     /locus_tag="PC366_002917"
     CDS             11876..13975
                     /locus_tag="PC366_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HDF2578414.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKETDRVYYVN
                     PKREELFGRKCYKMIQEVPEVVDCVVVCTPRNVVPSVLKDSGELGTKAAVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWALDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDDYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPANSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMKKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDDSVGFTMVGANIRDEE
                     NEMHETLCKAVSEAREQGLKKPVFAVPTLEGNRYLDYRTRLEDNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNTKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIKNRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(14242..14757)
                     /locus_tag="PC366_002918"
     CDS             complement(14242..14757)
                     /locus_tag="PC366_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HDF2578415.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLAAVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YAAPTNPPVTI"
     gene            complement(14849..16060)
                     /locus_tag="PC366_002919"
     CDS             complement(14849..16060)
                     /locus_tag="PC366_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HDF2578416.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIREIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKCLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVDFIKEMSDFPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
     gene            16736..18178
                     /locus_tag="PC366_002920"
     CDS             16736..18178
                     /locus_tag="PC366_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF2578417.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGLI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPNETKQRLKNVKKIY
                     IIGKELSISKSVETELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSAAQNNGDSSTKGESPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            18220..18573
                     /locus_tag="PC366_002921"
     CDS             18220..18573
                     /locus_tag="PC366_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578418.1"
                     /translation="MKKSNIFSIIFPTIIMVLMFLTFATDIFNIPDIQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTNWILSLIVSLVTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HITAKLYYKIKTFKN"
     gene            18764..19585
                     /locus_tag="PC366_002922"
     CDS             18764..19585
                     /locus_tag="PC366_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HDF2578419.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNVPVPSKAYFKGLSKEDAYYKYFNSILETNREFGDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDVIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFVNIKKVKSNNIA"
BASE COUNT         7532 a         2350 c         3366 g         6549 t
ORIGIN      
        1 tttttttatt ggaagattta tgttatattg agatgaattt attatgatat aaaaaataat
       61 gttaggataa atttaaatct ttttctaaaa atgtattaat ataattctta aagaaaggat
      121 ttttaacaat ggatataaaa gagttagtta aaatgcaaag aaaatattat aatacaggta
      181 aaacaagaga tatatcgttt cgtatagaac agttgaagaa acttaagtta gttgtatcac
      241 aaaatgaaga aaaaatactt ttagcactaa agaaagattt aaataaatcg aattttgaag
      301 gttttatgac agaggtaggc atgttttata gtgaattaaa ctttgctata aagaatataa
      361 gaaaatggag caaaataaaa agagttaaat caagtatggt taattttcca tctatatcca
      421 aagttgttcc acaaccttat ggtgttactc tcataatgtc accttggaat tatccctttc
      481 aattagcact tataccatta gtttggtcat tagcagcagg gaattgtgtt atattaaaac
      541 cttctgaata ttctgtgtca acatctagtg tagttaaaga catagttgaa aatacttttt
      601 caaaagaata tgttgcagtt gttcaaggaa gtcaagaaga aagtgaaaag ttactattgg
      661 aaagatttga ttatatattt tttacaggaa gtactaatgt tggtaaaata atcatgaaat
      721 cagcatcaga gcatttaact cctattactt tagaacttgg aggaaaaagt ccttgtatca
      781 ttttaaaaga tgctaatata gaccttactg ccaaaagact tacttgggga aaactaataa
      841 atgcaggaca aacctgcgtg gctccagatt atgttttagt gcatgaagat agaaaaaatg
      901 agttaataga gaaaataaaa tattatacta ataagtattt tggagataat ccatgtaata
      961 atgagcaatt tcctaaaatc ataaatcaga gacattttaa tcggatatta tctcttattg
     1021 ataaagataa gatagtctat ggtggaaatt ataataagga gacattaaag atagagccaa
     1081 ctatagtaga caatgttaat tgggatgata atataatgaa ggaagaaata tttgggccta
     1141 tatttcccat tttaacatat aaagatttag atgaagtaat acaaaaaatt atacaaatgc
     1201 caaatccatt ggcactttat atttttacaa aaaataagta cctagaaaat aaacttttag
     1261 aaatgattcc agcaggcgga tgttgtatca atgatacagt tactcatata gctacgaatt
     1321 acttaccttt tggtggtatt ggtgaaagtg gtatgggctc atatcatgga aaagctggat
     1381 tcgatacatt tactcactat aagagtgtgt taaaaaaatt aaatttggat gtccctatta
     1441 gatatgctcc atacgataat aaattaatta aggttcttaa aaagataatg taggttatat
     1501 tgtagaataa taaatataaa taaaattgag tatttgtatt ctgaatatat tttattttta
     1561 atttggtata tttgttataa aagtggtgat tttgtgataa aatttaatta tatagaaata
     1621 aggaggaaaa aatgaaaatt aattggaata caaaatacac aacaatagca atttatacat
     1681 ttataatagc tgctagtagt attatatttt atctagtatc atcacaaatt gatgtatttt
     1741 ctaataattt agatgctata tttacaacat tacaaccttt tataatagga tttgctattg
     1801 catatcttct taattttatt ttaaagtttt atgaagacag aatttttata aaaagtgaga
     1861 aattaaaaaa actaaaacaa agttcaaaaa gaggcttggg tcttttatta acatatgcaa
     1921 cagctacatt gatactttac ttatttatgc atttcgtatt gccacaagta attgagagta
     1981 ttgttggact agcaaatgat atacctatgt atgtaaacaa tgcaactaag cttattgata
     2041 aattaatgac tgatttaaat cttgatgagc aatactttaa tttggcagtt gataagtgga
     2101 atgagtttgt tacatatatt ataaagtttg taacagattt aatcccaata ttaggaagta
     2161 tgttaaagaa tgtagcctct agtatatgga atattgtact aggattaatt gtttcagtat
     2221 acttattaat tgataaagaa aaattctatg gattaagcaa aaaaataact tatgcagtat
     2281 ttacagaaaa acaagctgcc agaattttag aattaactca tagaagtaac tatacatttg
     2341 gaagattttt aggtggcaaa atattagatt cattcattat aggtattcta acatttgtaa
     2401 tacttacatt agttaaaatg ccatatacat tattaatatc agttataatt ggtattacaa
     2461 atattatacc tttctttgga cctttatttg gagctatacc atctactcta atagtgatgt
     2521 ttgtatctcc tataaaagct ttctggttat tgttgattat attaataata caacagatag
     2581 atggaaatat tataggacct aaaatacttg gagattcaat tggtatatct gcattttgga
     2641 ttttgttctc cttattggtt gcaggaaaat tattaggttt tattggaatg gttataggag
     2701 ttccaatgtt tgcagtaatt tattctataa ttaaggatat tgttgaaagt aaattggaca
     2761 aaaagggatt accgacagat acttccgatt acatgtagct aaaaaatatt atgtataatt
     2821 aaaaatatat aaattaagca atatttaaag cactgagaaa gttaaactct tggtgctttt
     2881 tagatataaa attattatag aagaggtgtt ttttgtggca tttatagaat gtaaatttaa
     2941 atctaaatat actggaggag aaactgatat aattgtaatt ttgcctgtag caaatggaaa
     3001 agaacttttt agtggtaaag agatatatga ttttgaaggt aaatttaaaa cattatactt
     3061 atttcatggt ttagaagatg accaaagctc atggattaga tatactaatg tagagcatta
     3121 tgctaaaaat aaaaatatag ccctagtaat accaagagta gaaactagtt tttatacaga
     3181 tatggcgtat ggacaccaat attttacttt tgtaagcgag gaattaccta aatttgttag
     3241 agctatattt cctttatcag ataaaaggga agataacttt gtagctggta tgtctatggg
     3301 gggatatgga gctttaaaat tagcactttc aaaaccaaaa gagttttcgg cagttgcaag
     3361 tttttctggt tcgcctgata tgattcatga gttagaaaat caacaaatag aaaccaatgc
     3421 agacatttta tttcacgatt ttggtagacc agaagacgct agaaatagtg agaatgattt
     3481 actttacata cttaagaacc ttaaagaaag aaatgaagat attcctaaaa tttatcaatt
     3541 ttgtggtgat agagattttt tatataaaaa taatcagatg tttaaaaaat atgcagagtc
     3601 tctgggtgta gatgttgaat atgaagagtg tgtagggggg catgaatggc gtctttggaa
     3661 tttatggata aagaaattta tagatataat tgggtagtac acttatggta ttaacaggta
     3721 tactataaaa tatctttaaa tatgataaag actgaaatcc taaaatcaaa ttatgatttt
     3781 aaaatttcag tctataagaa tttaataaaa ttttattaag ttcttacacg agttattatt
     3841 ggagtaaaat tgtcaactat atctatatag tatttactca attcctctaa aatctcttcg
     3901 cataaatccg tactatgacc aagattaata agaaactgtt ttgtaaaatg ctttattaca
     3961 gcttgagaag atatatcgta cttgtgtgaa gtataaactc taattatttc aggtttcata
     4021 gcaagtatac caatacaaga aagtattaat tcatcatgtt ctatagattc tttatcatta
     4081 acatatcttt tcatgaccat ttcggttaca cttctttgat agcttaaaat agcttcttca
     4141 taagctatat ccaaataaaa atttctatat gcttcgtttt ttagaaggaa acaaaggtca
     4201 gcattcatag caagaaagaa catcatcata gtaccttctt catggtagtt atagattaaa
     4261 gactgcattt catttcttat atcttcatat attatagctc ctatttcgct tttacttgag
     4321 aagtaatagc ttattagacc taaatttata ttagctcttt ctgcaatttg cctagttgtt
     4381 gtcttatgat aaccttgctc aaaaaataat tctctagcag cacttataat actagctttt
     4441 gtttctttgc ccttttctga ttttgacata tttactgtgt atacctctct tttcaatctt
     4501 tttttgaaaa tttgctaact ataaatattg taatagaacc acctattata ggaaccaaaa
     4561 ttctgtcaaa tacagtaaga ataccaatca tatttaataa tgccaatata acacttacta
     4621 taacagcata gatagctcct ttttttgtag cgcctttcca gcaaagacca attacaaatg
     4681 gtgcaaatat tacacctgta cataatggag ccggccaaaa caataattct aataaactat
     4741 caaatttaag tgctatgatt gcacctatta tagctgtcaa agctgatgca atttgagaat
     4801 actttagagt attttttaaa tcattaaatt ctatattagg atgtaataat ttgttataaa
     4861 tatctcttga tataatagca ctcattgagg tcattaatga atcggcagta gacattatgg
     4921 cagccaatat agcagctaag aataatacag atattaaagg tggcaaagta gtcgatatca
     4981 tttgaggtaa aacctgaaca gatgatatgt ttggaaataa actaccacca atagctccaa
     5041 ttattcctat agggaaggca agaaataata gtataaatcc tgcaattaca ctacttttaa
     5101 ctgcattttt agcattatca gcacattgat atcttaaaaa actttcataa gaaaatattg
     5161 agcctaaaac taatggtaaa actgtataca taaaatcact aatcgattta tttcctggaa
     5221 agaatggttc ttttaccatt gattgtaaca taagtaaagg gttgtcgcca actaatttta
     5281 agcttatata agctactatt ggcaaaaaca ctatacaaat agcaagttga ataaatgctg
     5341 atactgcaac tccccacatt cctgatgtat aagtatatat aattataact ataactccta
     5401 taattacagc tatatcataa ggaataccaa atgcagtaga tacagaacca aaagaaatta
     5461 attgactacc cataatagct agtatagata ttggtgttac aagactttga taagctctta
     5521 aaaatacact atgaccatat ctagtttcaa tataatcagc aggtgttata tcacaagata
     5581 agcttcttaa ttttcctgcg aaaaaggcat ttataaagca agctaaagct gcacctatag
     5641 tagaatacat tccaacccaa agtcctcttt cagctcccca ttgaactcca ccaactaagc
     5701 accctcctcc aaaagatgta gcagcaatgg ttgcagctag tataggcaaa ggaagatttc
     5761 tacctgcgat taggaaatcg gatgctgttt taactttttt tgaaaaataa aaaccaatcc
     5821 atatgtatat tgcacacgta acaattaaaa gtaacatagt cttttctcct ttataaaata
     5881 ttttaataaa atatataaaa tatatttaaa atatatttta tataaaagta gtacgatatt
     5941 tgttttattg gttttagatt aatatagcta taataattta tgatattaga tggaaattac
     6001 gtaaaaatag aaaattgaaa attctgaaat ttttgcatat tgatatttat ctcatagatt
     6061 cttttttgta attgtaacac gcttttattt ttaaatcaat agtacatgta taaaaataaa
     6121 aggaatctaa ataagaaaaa gatattttta atatctggat gtagtataga aatatcttga
     6181 ataaattatt cttgaataaa attataaaaa tttaaaatca ctagaaatat gataaaataa
     6241 tttaaaatac gcatttcaat gacatttcaa gacaagaaaa taataaaaaa caaatctaaa
     6301 ttaagcctaa atagcttttt agttaatttt agtagtaaaa aataaaactt aaaaagtgtt
     6361 tgacaattat gaattttaag aatataatta aattaaaatt atacacatat aaaaatatac
     6421 tcctgaatca agaatgagat atttaagatt caaaatatat attattatac gtgaataatg
     6481 aaaagtaaga aaattttata agggaggggt agatgtgagt agtcaagaaa gcaaaccaaa
     6541 aggaaatctt atatcaaatt ttagagatga tatgagagac cctaagaaaa gagcaatata
     6601 cacatattca agttctataa acttagcgta caattttata ggttactttg tatcaactgt
     6661 tacaaatatt tttttaactg atgtggcaaa acttggtgta attatggcag gtggtatgca
     6721 aattatacaa tctttcataa aaattgctgt agctcctata acaggtacag tatttgacaa
     6781 acaaccattc aaaaaaggaa agtattatcc atggcttaga tatgcaccag cagcgttagc
     6841 attaacatat ggaatatttt tcatagttcc attaatgaaa ataagtccag cattactttt
     6901 acctttgatg acagctttat tattaatagc atcttgtgct cagcaagtag ttttcactat
     6961 aatttatgct atttaccctg tagttgctaa gacacctaga gaccgagtta taggctcaac
     7021 tactactaat atatttaaag aagttggtaa attcttagta ggtttttcat atccgttatt
     7081 attagtttta tttgcagatg tattaggtgg agaaggaatg ggttatttag gtacctactt
     7141 attctttgca gcaggatgcc ttttagtatt ttggttttct tcaacagaga taataaaatc
     7201 tggagcagaa gaagaagttc ttcaaaaaga agagaagcca aagattaaag caagtgaaat
     7261 ggcaaaagct ctattcacta atgtaccact tatgatggca ttttgtttag aatttcttat
     7321 atgtataaga tctataggat taggaccttt ggctccatat tattttaaat atgtaataga
     7381 agatgaacgt ggattagcag tatttttatc aatcatgcct ttggtaagtg tagcattcat
     7441 gtttttcgca ccagtgttta taaaaatctg tagagagcaa aaactagctt caataatttc
     7501 tttttctata tgtgcactat gccacttatt ggttgcatgg actccttggg ggaaaactac
     7561 tttaggagta actatgttgc tggcaattgg tggaggtttt tcaaatgtag tatcaataat
     7621 aaatcttaat ttctttgccg gttcttgtga ttatgggcat tggaaatcag gaaaagactt
     7681 acctggctta agtatgtcac tatatccagt tgcaatacaa gtaggagtat tacttgcaac
     7741 tactataaga acagttttaa tgaactcaat gggatatcaa gctgatatgg tagtcacaga
     7801 agcagttaaa tcaggtttta taaatatgat ttcttattct atggcaatac ctttaataat
     7861 agctgttgtt atagcaatac tatatccagt aagtgacaag aaattaaacc aaataagaga
     7921 agagttaaat caaagaaatg cttagttaaa agaaagttaa gtagatggtt aatttaagct
     7981 attaaagtaa gtagacgcaa tagcgtttat ataaatcaaa atacatatac agagggggct
     8041 tttaaaaatg atagaaaaat tattgagaaa taccgtaaaa gaattacatc aatatgttcc
     8101 aggtgaacca atagaaaaag ttaaggaaaa atatggtgta aaagaaataa taaaattagc
     8161 ttcaaatgaa aatcctctag gaccatcacc aaaagcaata gaagctatga ttgaaatgct
     8221 aaaacaaggt caactttatc cagagccaga agctaacgaa cttagaagaa aattagctga
     8281 aaagctagat ttaaaaccag aaaattttat tgttgctaat ggtgcggata acgttatcac
     8341 tctaataggt gaggctttta taaatagagg agatgaagtt atatattgta acccaacatt
     8401 tccatcatat agaactgcaa ctataaaaaa tgaagggata ccagtagaag tgcctttaac
     8461 agaagattat aagtatgatt tacaaggtat attagataag attacagata aaacaaaatt
     8521 aatatgtgta tgtaacccta ataatccaac aggaacaatt gtggatgata aagagttaga
     8581 agaattttta aagaaagtcc ctgaaaatat tataactata ttggatgaag catatataga
     8641 atttttaaca gttcctaatt atgtggatgg acttaagtat gtaagggaaa attataacgt
     8701 tatagtaaca agaactttct ctaaaatata tggtcttgca gggcttagag taggatatgg
     8761 tattgctaaa gatgagataa taagaacttt atttacagta aaagagcctt tctctgcaaa
     8821 tcgtgttgct ataagtggag caacagcagc acttgatgat gaagagttta taaaagaaac
     8881 atatgaatta aatagagttg gaatgactta ctttaaagaa gagtttacaa aaatggggtt
     8941 tgatgttgta gattcacaat caaatttcct ttatgtagat atgaaaacag atatacctaa
     9001 gttatttgaa gacttgaaaa aaagagggtt tgtaataaga ccaagtgcta cacatgcacg
     9061 tgtaagtatt ggaactatgg aagaaaataa gaaatttgta gcagttttaa aggaaatatt
     9121 aaatattaaa ggagagccaa gtattggata atagatagaa atattatgaa acggggtgta
     9181 gatatgaact taaaaataaa cgcagagaga tgtaaaagtt gtgaatactg cgttatatct
     9241 tgtaaaaaag gagcattaaa aatatcaagt aagataaata aagaaggtta tgctcatgta
     9301 gaagttgatg agagtaaatg catactttgt ggaatttgct atcaggtgtg tccagataat
     9361 gtttttgaaa taattaaaga aaaagcatgt caagaggctt agaaggagtt gggataatat
     9421 gaaaaagatg tggaagggga accacgccat tgcagaagca gccctaagag gaggttgtga
     9481 attttatgca ggatatccaa ttacaccaca aacagaggta atggaatttt tatcacatag
     9541 aatgtctgaa cttggaagaa cttttataca gtccgaaaat gagatggctg ctatatatat
     9601 ggtatatgga gcatatgcaa gtggaatgag gtctatgacg agttcttcag gaccaggaat
     9661 atctttaaaa caagaaggga tttcttactt atgtgcaaat cattaccctt gtgtaatcgt
     9721 aaatgtacag agatgggggc ctggtcttgg ctcattggac tcagcacaga cagactatct
     9781 aagagatact agagggggag gaaatggaga ttatcatttg atagtttatg caccaaacag
     9841 tattcaagag actgtagatt tgatgtataa ctcatttgat gtagcggaaa aatacagagt
     9901 gcctgtcgaa attttgacag aagcagcttt aggtcaaatg atggaaccag tagaatttcc
     9961 agaatttaag aagagagaag gagatttagg ttggacttat gatggaagta atagagacca
    10021 tgcaaaggtt gcagataacc aaaagccaac tttttgtatg gagaaacgta tgagaataac
    10081 tgaaaatgaa caacaatggg aagattatca agtagaagat gcagaatatg tgtttgtagc
    10141 gttcggtata ccatcaagaa caactatgaa tgctgttaga agacttagag aacaaggtga
    10201 aaaagttgga ataataagac caataacagt atggcctttc ccatataaag catttgaaaa
    10261 ggtaagtaaa gatgtaaaag gatttatctc agtagaatca acagacacag gtcaattagt
    10321 agaagatgtt gctttagcct caaagaaagt atgtaaagaa aatgtacctg tgtatggttt
    10381 atttagtgga aatcatatac caaaaacatt gcaagtaatg gacacttata gcaaaataaa
    10441 atctggcgaa atcaaggagg tgttctaata tggctacaga aaaattaaca cctagcgttg
    10501 tttcaatacc aaacaagttt tgcccaggtt gtggtcatgg aatagtaaat cgtataatag
    10561 cagaggtaat agaagaacat ggatatgaaa aaaatcatgt attaacatta ggagttggtt
    10621 gtgtctgcaa tatgaatttt agctggaatg gtgataagat gcaaactgca catggtagag
    10681 cttcatctac agctatagga gttaaagtag cacttccaga tacattagta atgacttacc
    10741 aaggtgatgg agatgcttat gttataggtc tttctgaaac tttaaataca gcatatagaa
    10801 atcataatgt gactgtattt gtaataaaca ataataattt tgcaatgact ggtggacaaa
    10861 tgtcatggac cactatgccg ggtcaagtca caacaacaag tgtaaatgga agagatataa
    10921 agactactgg tagtccactg aaagttcctg agatggtggc aaacttcttt gatgtagcat
    10981 atgtagcaag aggttcagtt catagcccaa aggaaataat taatctaaaa aaatatataa
    11041 aaaatgcaat agaagctcaa ttaaatggag agggatattc cttagttgaa atattagcac
    11101 cttgcccaac taactggggt gtatcactag agaaatctat caaatggatg gaagaagaaa
    11161 tagtgccata ttatgctctt ggcgaattta agcaaaggga tggtgaatag ttatggaaaa
    11221 agagctagta tttgcagggt ttggtggtca aggagtttta actcttggtc tgattgtagc
    11281 tgagtcagca cttgaattgg ggaaacaagt aacttggatg cctgcatatg gtccaactat
    11341 gagaggtgga aaagcctata gtgtagtaaa gttttctgat gagagtatag gtgggcctga
    11401 tatggaagaa atagatgttt tagtagcaat gaataaacca tctttagatt atataaattt
    11461 agttaaagaa ggtggaacag tagttattaa tacatctgca atagatgaga atgtaacatt
    11521 aagagaagat ataagtgtag ttaaaataaa ttgtcaggaa ttagctcaaa aagtaaacaa
    11581 tccaaaagca gcaaatatag tagtacttgg agcattaatt gctaaaactg ggttacttga
    11641 aaaagaatta gctttaaaaa ctatgtgtga tttctttgag gaaaaaggaa aaggaaagtt
    11701 taatgttcaa aatgaagcag cattcatgga aggctataat aacgccattt gataaattac
    11761 ccttatctta agtgatttat ctcaagattt aataatcttt agtgccaaga gaaacttcat
    11821 cttgagataa aattcactta aaatcacaac tataaacata taggagcgtg aatttatgag
    11881 tttggaaaaa cttattagac caaaaagtat tgctatagta ggagtgactg ataaacttgg
    11941 ttttggaaga agtgcagcac ttagtatagt aaaaagtaag gaaacagata gagtatatta
    12001 tgttaatccc aaaagagaag aattgtttgg gagaaaatgt tataagatga tacaagaagt
    12061 tccagaagta gtagactgtg tagtagtatg tacgcctaga aatgtagttc catctgtatt
    12121 aaaagattct ggagagttag gaacaaaggc agcagtggta tatgctagtg gatttgcaga
    12181 ggaaggtaca gaggaaggta cagatttaga aaatcaactt atagaaatat caaatacata
    12241 cgatatgaaa atattgggtc caaactgcat ggggttgcta aattgtatag ataaggttaa
    12301 tctatgggca ggaggttcta aatgggcttt agatactaaa aaacctggta taggaattgt
    12361 aggtcaaagt ggatttataa ctgctgaaat tgtttcaagt gattatttta atatatctta
    12421 tggtttttca acaggaaatg gaaatatagt tacactagaa gatgcagtag atttccttgt
    12481 agatgatgat tatgcatcag taatagcaat ttaccttgaa ggtttaaaaa atcctcaaaa
    12541 atttatagat gctttaaaaa gggcagcaca aaaaagaaag ccagtaataa tattgaaatc
    12601 aggaaggtca gaaaaaggtg ctatttctgc tgcctctcat acaggaaatt tagctggttc
    12661 gagtaaagct tttgaaagta tttttgaaaa atatggagta atttctgtgg aaaatttaga
    12721 acagtttatg tgtttagcac aagcttttag tgttttagat ggtaatttac ctgcaaattc
    12781 taattttgca gcaataaact tctcaggagg agaaaatact atttgtgcag atttagcaga
    12841 agaaaatggt gtagaacttg cagaaatatc ttctgaaact aaagaagaaa tgaaaaaata
    12901 tcttccagga tttgcaacac ctaaaaatcc actagatgct acaacagcat tattccatga
    12961 aaaggatatg atagtaggtt tattacatac ctttgaaaag gatgatagtg ttggatttac
    13021 tatggtaggt gcaaatataa gagatgaaga aaatgaaatg catgaaaccc tttgtaaagc
    13081 tgtaagtgaa gctagagaac aaggattgaa aaaacctgtg tttgcagttc ctacacttga
    13141 aggaaataga tatttagatt ataggactag attagaagat aatcaagtgc ctataatgtc
    13201 atcagttgga actacattta cttgttttaa taaaatggct aagtttatag attatgatta
    13261 ttcaaaaaga actttagaat ttaaagctgt taagaaaaga gagtcaaata atgtagtagc
    13321 attatcagaa ttagatagta agattgagat gaaaaaatat ggagtaccag ttccaggaca
    13381 aggtaataca aaaagtattg atgaattaga tgaaatctta aaatatatta agtatcctgt
    13441 tgttttaaaa ataaattctt ctgaaatatt gcacaaatct gatgttggag gagttaaaat
    13501 aggaattaag aatagagatg aggcagtaga tgcatataat gagattttaa ctaatgtaaa
    13561 aaaagcaaaa ccagatgcta atattgatgg tatattagtt caagaaatgg tagaaagtgg
    13621 tatagaaatt attattggta taactaatga tgaccaattt ggaccaatgt tattagtcgg
    13681 tttaggagga gtatttgtag aggtatttaa agatactaca ttatatccat tacctataaa
    13741 tcatgatgaa gctattatga tgcttaaaaa actaaaatca tttaagcttt taaatggcta
    13801 tagaggaagt gagccttgtg atattgatgc tcttgcagat atgatggtca aattaggaaa
    13861 atatgcttat gaaaataagg atgaagtcaa ggaaatagac ttaaatccag tgtttgtata
    13921 tcctaaagga aaaggcgtat gtgcagtaga tgccttaata gttaaatata aatagtttat
    13981 aagttttggt attcaaccat aattaaagca ccgactgaaa atcacatttt gtaagttaga
    14041 tagtgtgatt ttcagtcacc ccaaatttaa tttaaaaata ttttaaaatg aaagtatagt
    14101 tttgagttta attgtgaaat agcactgtat aaacaataaa atactacgta taaaacgaat
    14161 aataaaaggt gttttaatga taagaatcaa tcttgatttt cattaaaaca ccttctttat
    14221 tatattaaaa atttttaaac gttatattgt cacaggtggg tttgttggag ctgcatatgt
    14281 acgattagca aattcttggt caacaaagaa tagaccaccc tctccagcaa gtttaacacg
    14341 ttttatattg tcttcacaat ttgtttcttc ttctgcttgt tcagatataa accaaagtaa
    14401 gaattgagaa gttctaaagt ctgattcaga gtttgctaca gctgctaagt tgtttattaa
    14461 agctgtaacc tttttttcat gagctaacgt acgctcaaga atatccattg cagaagtaaa
    14521 gtctgaatct ggcattggga tagcatcaag ctgaaccttt cctcctacat tatgtaagta
    14581 tttgtaaaaa aacatagcgt ggtctgtctc ttctttatat tgaacataaa accaattaga
    14641 aaatccttta agtccttctg cttcaaggta agaagacata gaaagataaa gatacgcaga
    14701 atataattca tggttaatct gctcattaag taatttttcc attttagctg aaatcatttt
    14761 tatacctcca aattttaaat gctcttataa aatataataa tattaaatgg aaaaatattc
    14821 aataaaagtg tttaaatatt ttacatattt aataaaaatt tatactacca ttaaaaaaat
    14881 tataacttac aatggctata gagccaatta atggtgcatt tgctccaaaa tttgaatgcc
    14941 ttacacttat ttttttatat ttagaaaaac ttgctgaagc agtcaatttt tttaataatg
    15001 tattttctat aaatgtacca ggtatattaa agtcatagcc tattattata gaactacaat
    15061 caatcaatgt aagtgtatta actaatgcat atgatacgta tgtacaaaat tcatcaagca
    15121 aaaacatggc aagactatct ttattatttg cctcatctat taacttgact aaagaaaaat
    15181 ctttacagtt aattaatggg gagttaggat aaatatggct caatgattca attcttttaa
    15241 ttagattact gacacttgta taataatcta aacatccatt gttaccacaa ctgcacaatg
    15301 gtccactaaa attaattgat gtatgtccta tttctccact ttgtcctagg ttgccagtat
    15361 gaagtttatt ttctagaact agaccagctc caataccatt cattatgtgt aggtatatat
    15421 aatttgatat atttttacct aaaccataca ttttttctgc taatgcaccc gaattagcat
    15481 catttatcaa aaatattgga aaatcagaca tttcttttat aaaatctact atatttaggt
    15541 ttgatacatt tccaaagtct gggggattta gtatggtacc atttatatca tctactggac
    15601 ctattgaaga aataccaatt ccaattatat ctctcttgtt gattttcatt attttagtaa
    15661 acattctttt tattatatct tttaaaacat catttgatag acatttaggg taagtttcag
    15721 aaagttgttt tacaatatta ccttttaaat ctgaaataat taccttacat atatttcttc
    15781 ttattaggat tccacaaata caaggcgata tattagaaat atctaataaa ataggtttac
    15841 gacctgatga atgtgcattt aaagttgatg actctatttc cctaatcata ttttcattaa
    15901 taagttcagt aactagattt gataaagtca ttttagtaag tcctgtagac ttagctaaat
    15961 caactctgga cataggtgta tttgtagaaa gtaatttcaa tattattaac ttatttttaa
    16021 tttttacatc tttgatgtta gaaccttgtt tgttactcat cataaatctc cttaaataaa
    16081 gttaagtgtt ttatttattt tcaagtatac tatcacctta taatagagta acattttttt
    16141 acttgaaaat atcattaatt agaatatatc acattatata tcataaaaca tataaaaaaa
    16201 tgttagaatt aaattaaaag tgaaaagtag attgatatat aaatagtaaa tacttaatta
    16261 aaaaaagata atgatagcaa taattattgt taccaagaat ctactacttc aagtgttacc
    16321 ttaggtattt aagttgatag tggtttgcac gtaataaact tgatgtaata tatattctta
    16381 ataatatcga taaaagattt acttaaaaat aatatagatt atgtaaacat ataatctatt
    16441 tattgtatac aataaaattt cattttgtaa aacagtgaat taaatatgta atatagatat
    16501 cgatttttat tacaaattgt tactaaatat aggtacatta gaacaaaaat ctagtaaatt
    16561 gtaactaaaa tgtaaatttt tcctttaatc tatacaatat tatggaaact ttttgtaatt
    16621 tatgatataa taacaaatat ataattatta aattataata aatgactata gcgtagatgt
    16681 aatactatgt tatagtcatt tttgaattaa acttgatata tcaaggggga agaatatgag
    16741 aacaattaga agagttttag cattaggttt aacattagct atatttctaa taaatgtacc
    16801 taatgtagat gcattaacat cagatacaat taaaggtaac aatatatatg agacggctgg
    16861 attaatagca gataaaaaga gttatgatac agcaattatg gtaaatatgg ataattctat
    16921 agcagatggt ctttcagcaa gtggtcttgc aggtgctgtt gatgctccaa ttttgcttgc
    16981 acaaaaaaat aagataccaa atgaaacaaa acaaagatta aaaaatgtta aaaagatata
    17041 cataataggt aaagaattat caataagtaa gtcagtagaa actgaactaa aaaacacagg
    17101 ggcacaggta actagattgg gtggagatga cagaataaag actagttata gtgttgctaa
    17161 agaggtaaat ggtatcaaaa aagttgatga agtgatatta actaatgcat ataaaggaga
    17221 agcagataca ataagtgctg cacccgtatc agtaagagat atagctccta tagtacttac
    17281 agatggaaag agtgtgcctt tttcaacaag caatgtaaaa acatatgcag taggtgggag
    17341 tatatcaatg agcactagtt tagttaataa aactaatgct aaaagacttg gtggttcaga
    17401 tagatatgat acaaataaga aagttataaa agagttttat ccagatgcat cagaatttta
    17461 tttgagtgat ggatatgatt tagtaaatgc acttacaggt tctacaattg ctaaggaaaa
    17521 tccaattgta ttggtgtcag aaagtagtga taagtctata ttagcaggag cagataagat
    17581 tactagatta ggttcaataa gtgacagtgt gtataataag tgtgtttctg ctgcacaaaa
    17641 taatggcgat tcgtctacaa aaggtgagtc acctatgaaa aatgagacaa gcatattagg
    17701 tcagccaaca gctagtttag aagcgtgctt aaaatgggca aaatctaaaa aagctaatga
    17761 tttatttata gagttaatac caatattata tgatactgct gttcaggaag gtgttaatcc
    17821 tgttttggca gtagctcaat ctgcaaaaga aactggtttt tgtaattttg gtggagtatt
    17881 agatgcatca tttaagaatc cttgtggact taaaacttct gtaggtggtt ctgatactga
    17941 taagaatgcc cattcaagat ttgatacttg ggaagaagga atattagctc aaattcaaca
    18001 tttatgctta tatgcaggac aagatggtta cccactttca aatccagtag accctagaca
    18061 tgaaaaatct ttatttggta aggctaaaac agttgaaagt ttatctaata attgggctgg
    18121 aggtcaatat ggacaagatt tagtaagaat gatgggagaa attgaggcaa caaaataatt
    18181 gaagattatc aaatatccaa taaataagga ttgattatta tgaaaaagag taatattttt
    18241 agtatcatat ttcctacaat cataatggtg ctaatgtttt taacttttgc tacagatata
    18301 tttaatattc cagatattca atctaaaagt atttttgttg tgggaatggt tttgattttt
    18361 ccaatttctt ttttaataca agggataatt tgtgtattaa ataagactaa ttggatttta
    18421 tctcttattg tgtctttagt aacttatata gtattaatgt atatattttt aaatgattct
    18481 gcatatatat atgttttact ttatacagct ttttatatga ttggacatat aacagctaaa
    18541 ctctattaca aaattaagac ttttaaaaat taaattgaag tatataaaag taacattaag
    18601 agaagtatcc ttaatgattt tctaaaatca gaaataggtg cttctctttt ttgtaaaaat
    18661 aaaagtatgt aaataaaatt taaccattat aattttcttt taacaaatgt atacaataaa
    18721 cttgttgtat aattaagata gataaaataa agggagggat aatatgaatt taatagataa
    18781 tcatattcat actaattttt caagtgatgg aaaggattcc atggaagata caataaaaaa
    18841 agctataagt attggtgtta gatatttgac ttttacagac catttagaac atgatgaaga
    18901 tagaggattt tgcataaatt ataatgacta tgttccagta tttaataagt ttaaagaaaa
    18961 atataaaaag gatatagagt tattactagg tgttgaagta ggttacagaa aacatctaaa
    19021 aaatgaaata gaagaaataa taaattctaa tccttttgat tttgtattgt gctcaactca
    19081 tacaattgac aatgtacctg ttccatcaaa ggcgtatttt aaaggtctta gcaaagaaga
    19141 tgcgtattat aaatatttta atagcatact tgaaactaat cgtgaatttg gagattacaa
    19201 tatatatggt catttggatt atatatctag gtatggaata tattcagata atagagttat
    19261 atacaatgac tttaaagatg ttattgatga ggtcttaaag tcaataatca ataatgggag
    19321 tggtatagag ctaaatactt ctggttatag atatggatta aatgctatac atccaaatga
    19381 agatattcta aaaagatata aagaacttgg aggatttata gttactgtag gttctgattc
    19441 tcatagggta gaagatatat gtaaagattt tgatgtggcc tatgatatgc ttaagtatct
    19501 tgactttaaa tatgtatctt tatttaaaga aagagaaact tattttgtaa atataaaaaa
    19561 agttaaatct aacaatatag cttagagtat gttttgaagt aaattaatgg atagttaaaa
    19621 agttaatagt tataatattg tatcctctag aaaaatacta gaggttttta ttttgctaaa
    19681 ataactaaat agaattaaat ttaaatagta tagtttattt taaattgaat agtttattgt
    19741 tgatatattt tactattata tatttttatt gtgatataat agtaaaatat attaacc
//
LOCUS       DAMJWO010000079        19246 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.081, whole genome shotgun sequence.
ACCESSION   DAMJWO010000079 DAMJWO010000000
VERSION     DAMJWO010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19246
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.081"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(18..860)
                     /locus_tag="PC366_002923"
     CDS             complement(18..860)
                     /locus_tag="PC366_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2578420.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKSK
                     IERTFVIQDESFLDKISKLASQVDEKFFEISTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENITIKNDLLHEIKRIHKKEYEIGKWAVDYINKEFDVKFPVDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     KEKINDTNNEIIDIIKVKYEKDYDCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
     gene            complement(1107..1601)
                     /locus_tag="PC366_002924"
     CDS             complement(1107..1601)
                     /locus_tag="PC366_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDF2578421.1"
                     /translation="MSTLVTLLGLLVCTKISTVFSKKWSNIPLAIYQIVLGIILSILP
                     FKLSFSFNPEIFVICIIAPLLFSEGQNVSRKELLELRKPILLLAFGLVLITVFAGGIF
                     IHFLIPRMPLSVSLALAAVISSTDLVAVKSITQGLNFPKNMMSILEGESLLNDDDRII
                     NIME"
     gene            complement(1753..2724)
                     /locus_tag="PC366_002925"
     CDS             complement(1753..2724)
                     /locus_tag="PC366_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HDF2578422.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFDKEIKCVKAVDGISFDLKKG
                     ETLAIVGESGCGKSTAGRTILRLIEKTEGKVEFNGVDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHNLVPKNEIKDNILNVVESCGLSKYHLNRKPDEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKGELYLHSQHPYTRALMSAVPVQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEIPVLKEISRNHFVACHLV"
     gene            complement(2725..3702)
                     /locus_tag="PC366_002926"
     CDS             complement(2725..3702)
                     /locus_tag="PC366_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578423.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNEVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFRGKDILKMNEDELMVIRGNEISMIFQEPMTS
                     LNPAFTVGSQIIEGIMIHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVLVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPVLGKNKDKRLYSIPGQV
                     PNPIGIPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
     gene            3921..5480
                     /locus_tag="PC366_002927"
     CDS             3921..5480
                     /locus_tag="PC366_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2578424.1"
                     /translation="MKFKKLASLILVSSLMLTFTACASNDKDKSSGSKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNAD
                     YFGGEPKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQDTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAEIDAL
                     WEKGFTELNKEKRKEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIKDAKPSPAI
                     LFEDWSKLYVE"
     gene            5586..6545
                     /locus_tag="PC366_002928"
     CDS             5586..6545
                     /locus_tag="PC366_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2578425.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     SQDIENIRVNMGLDKPVYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            6548..7360
                     /locus_tag="PC366_002929"
     CDS             6548..7360
                     /locus_tag="PC366_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2578426.1"
                     /translation="MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQRHIFDKLYLAVFPGLLIFLTVISLTIISKKFSSNT"
     gene            complement(7575..8477)
                     /locus_tag="PC366_002930"
     CDS             complement(7575..8477)
                     /locus_tag="PC366_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2578427.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKVRIGIPPL
                     ILGIAFSDVVAQLVANNPDIEFDIVEKGAYDLNRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNHPITWKVILCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            8832..10010
                     /locus_tag="PC366_002931"
     CDS             8832..10010
                     /locus_tag="PC366_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HDF2578428.1"
                     /translation="MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVGLN
                     LSEIDEVIIGNVLQTGLGQNVARQIAINSGIPNSVPSYTVNKLCGSGLKSVQLAAQSI
                     TSGENDVVIAGGTENMSQAPYIVPTARFGSKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDE
                     YPKLGMTFEGLAKLKPAFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKI
                     KSYASAGVEPEVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR
                     "
     gene            10019..10675
                     /locus_tag="PC366_002932"
     CDS             10019..10675
                     /locus_tag="PC366_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HDF2578429.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKITIVEADEIVEIGDIDPNEVNTPGIFVNYIVEGGNL
                     "
     gene            10675..11340
                     /locus_tag="PC366_002933"
     CDS             10675..11340
                     /locus_tag="PC366_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HDF2578430.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDNVNV
                     ILQSENGFLGLGSAEDGNSSDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     ILGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPAFTLDDVISATEAPLILSDSLNGKI
                     SVV"
     gene            11445..12221
                     /locus_tag="PC366_002934"
     CDS             11445..12221
                     /locus_tag="PC366_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HDF2578431.1"
                     /translation="MVKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALNNT
                     ITELQKKGYDCMSVKCDVTKEEEINHAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            12283..13617
                     /locus_tag="PC366_002935"
     CDS             12283..13617
                     /locus_tag="PC366_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDF2578432.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVLLNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKVGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSIVGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSKLEEESLDRELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            14114..15040
                     /locus_tag="PC366_002936"
     CDS             14114..15040
                     /locus_tag="PC366_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein"
                     /protein_id="HDF2578433.1"
                     /translation="MMRRNIPTKLKTILALGVLTLATASSAVTASASSLENNVNISNK
                     SLVYSNTKYKFSAKPNCSVKPELKPDKDNSCKDKNHNDKNCNNTNKPEDNNNSDSTNK
                     PDNNKPESNKPEDNNNSGSTNKPDNNKPESNKPEDNNNSGSTDKPNNNKPESNKPEDN
                     NNSDSTNKPDDNNNSGSTSENFSAYQKEVVDLVNIERAKAGLNPLTLDSSISNVATKK
                     SQDMIDNNYFSHNSPTYGSPFDMLKKFGISYKTAGENIAMGQKTPKEVVNAWMNSEGH
                     RKNIMNPNFSKIGVGVAQKSGGSIYWTQIFVG"
     gene            complement(15432..18971)
                     /gene="nifJ"
                     /locus_tag="PC366_002937"
     CDS             complement(15432..18971)
                     /gene="nifJ"
                     /locus_tag="PC366_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HDF2578434.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLIAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     GIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGITMSHLRFGDTPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHACIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRIQV
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKVDVMPANT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMDICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVLEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
BASE COUNT         6692 a         3003 c         2734 g         6817 t
ORIGIN      
        1 tattaaacta ctctttatta taaattcagt acagatataa ctcttttgat atgtaatgtt
       61 aaataaagta gttcatcttg acttacatag taatcataat tcttttctac atgagttttt
      121 attttatatg cacaatcata atccttttca tactttactt taattatatc tataatttca
      181 ttatttgtat cattgatttt ttcttttttt actaatcgtt ttgcaaagaa ttttaaatga
      241 gtcaaaagcc tatcataatt tatatcatct tctttaaatt caactctata ataatatctt
      301 ataatattta gtatgtcttt tacaatttta gtaattaaca gtgattcctt tgaacttccc
      361 ttatagtttg aatttactat atgcattgct ataaaaccag cttcatctac tggaaatttc
      421 acatcaaatt ctttatttat ataatctaca gcccatttac caatctcata ttctttttta
      481 tgtattcttt ttatctcatg tagtaaatca ttctttatag ttatattttc atgatatctt
      541 ttaattgcaa atgcaatatg gtcagtaagt gctacataaa tatattcata aagcttagta
      601 ttcaaattct cctctgcata agcaattatt tcagtactaa tctcaaaaaa tttctcatca
      661 acctggcttg ctagtttgct aattttatct aaaaagcttt catcttgtat tacaaaagtt
      721 ctttcaattt tacttttatc tatttcttga cctttctttt tttgaaaccc aatcccacat
      781 cctgttagta ttaattcttt ttttatattt tcatctaaaa ctaatacaac attattatta
      841 taaatttgtt gaataatcat aatcaatatc tctcccaaaa tacaatttcc cttattcata
      901 aaaaaatacc taaattaaga tacaattcac ctgtatacct taacctaggt attgcctgct
      961 taccagtaac aatccagctt gttaattctt atatattgta ttcaatttat ggttttattc
     1021 tattataaat aaatatatat gtcaagtaaa ttattgaaaa ctatttccta ttttttagta
     1081 ttatttttaa catcaaaaat caaattttat tccattatat ttatgattct atcatcatca
     1141 tttaataaag attcaccttc aagtatactc atcatatttt taggaaaatt taatccttgt
     1201 gtgattgatt ttactgctac taaatcagtt gaagatatta ctgctgccaa agcaagtgaa
     1261 acagataatg gcatcctagg aataagaaaa tgtataaaga ttccacctgc aaacacggtt
     1321 atcaaaacta aaccaaatgc aagaagcaaa attggttttc taagctctag taactctttt
     1381 cttgatacat tttgtccttc actgaataat aatggagcta tgatacatat tacaaatatt
     1441 tctggattaa atgaaaatga taatttaaac ggcaaaatag acaatataat ccctagtaca
     1501 atttgatata ttgcaagagg aatattactc cactttttgc taaatacagt tgaaatcttt
     1561 gtacaaacca ataatcccaa caatgttact aaagttgaca taactacctc tcttttcaat
     1621 aataatatta taaattaaac ttatatatca actaacttaa tattaacaac atgaaatccc
     1681 atcttaatca aaaaaatttt cagtttattc tattattctt attatataca tcaaatttaa
     1741 tttttgaaat atctatacta gatggcatgc aacaaaatga tttcttgata tttcttttaa
     1801 aactggaatc tcttttttgc atatttcctt acaataaggg catcttgtat gaaacttaca
     1861 tccacttggt ggatttgttg gagatggtat gtctcctttt aatataattc tatttttctt
     1921 aattgtaggg tcttgtactg gtactgcgct cataagtgct cttgtatatg gatgttgaga
     1981 atgtaagtaa agttctcctt tagttgcaat ttctattata gaacctagat acataacaca
     2041 aactctatgt gcaatatgat ttactacact caaatcatga gatataaata aatatgagag
     2101 tttatattta tcctgtaaat ccataagtaa atttataatt tgagattgaa tagaaacatc
     2161 tagtgcagaa acaggttcat cacaaactat aaattctgga tttaatgcta atgctcttgc
     2221 tatacctatc ctctgtcttt gacctccaga aaactcatct ggttttctat ttaaatggta
     2281 cttagaaaga ccacaacttt ctacaacatt taatatatta tcttttattt cattctttgg
     2341 cactaaatta tgttctataa ctgcctctga tattatttgt tccacattta atcttggatt
     2401 taatgaacta tatgggtctt gaaatatcat ttgcattttg ggtcttaact ttctaagttc
     2461 ttccttctct aacttatata tatctacacc attaaattca actttacctt cagttttttc
     2521 aattaatcta aggatggttc ttcctgcagt tgattttcca catcccgatt ctccaactat
     2581 agccaaagtt tctccttttt ttaaatcaaa agaaattcca tctactgcct ttacacattt
     2641 aatttcctta tcaaataatc cagatttaac ttcaaagtac tttttaagac cttctacttt
     2701 taataaactc tcttcttttt tcaattatat ctcctccttt ttatataacc aacatgcaat
     2761 actatgacca ctattcaatt ctattaaagg aggtatctga gttctacatt tatcacatac
     2821 tttttcacat ctatcactaa aataacatga atctggtatt ccaattggat ttggtacttg
     2881 tcctggaatc gaatacaatc ttttatcttt gttttttcca agaacaggct ttgattttag
     2941 aagtccaata gtataaggat gttttggatt tttaaataat tcaacaacct ctgccacttc
     3001 tataatttta ccagcataca tcactaatac tttgtcacac atttctgcaa ctactcccaa
     3061 atcatgtgtg atcatcatta tagatgtgtt taatttttct tttatatttt tcattatatc
     3121 taaaatctga gcttgaatag taacatctaa agctgttgtt ggttcatcag ctataagtaa
     3181 ttttggatta catgataaag ccatagctat cattattcgt tgtctcatac cacctgataa
     3241 ttcatgtgga tatgaattat atatttcttc agctcttggt atttctacca gttttatcat
     3301 atcgattacc tttttcttag cttcttcctt tgataaatct tgatgtatca taataccttc
     3361 aatgatttga cttccaacag tgaacgctgg gtttaaagat gtcattggtt cttgaaaaat
     3421 cattgatatc tcattccctc ttattaccat aagttcatct tcattcatct ttaaaatgtc
     3481 tttgcctcga aagattattt ctccaccttc tatttttgat gttggaagta acttcatcaa
     3541 agacatggct gttacagact taccacatcc tgattctcca actattccaa tagtttcacc
     3601 ttcatttata ttaaaactta cttcatttac actctttaca atccctttat ctgtatgaaa
     3661 ataaactttt aaatctttaa cctcaattag tgctttactc attattttct cctctcagca
     3721 aaattactta aaataacata caccttttga ttgtatttta taaaaattta aattacaaca
     3781 ttttcttaca ttttattatt tttttctatt aattataata atataatagt taatttctat
     3841 atatattgat ttaataatga ttactattat acaatgaaaa atatgtgtta aatattattt
     3901 tatggaggtt ttataagaat atgaaattta aaaaattggc atcattaatc ttagtttcat
     3961 cattaatgct tacatttaca gcctgtgctt ccaatgataa agacaagtct agtggaagca
     4021 aatctggtgg aactgttgta atacctatgg caagtgaccc agatataatc aatggagctt
     4081 ttgcaaacgt taaagaagac tctcttgcat caaatatagt ttatgctcct ctttatactt
     4141 atgaaaaagg gaatttagta aattatttag cagaaaaagt agattttaaa gatagtaagg
     4201 aattaactat aaaattaaaa tccaatttaa aatggcatga tggaaaacca ataactgctg
     4261 aagatgtctt atttacattt aatacagttt tagacgaaaa acaaaattca ccatcaagac
     4321 aatacttatt ggtgggtgaa aaaccagtta aagtagaaaa aattgatgat ttaacagtta
     4381 agattacttt accaactgca agtgaatctt tcttatatgg tatatctaaa atttctccaa
     4441 taccaaaaca tgtatttgaa ggagaatcaa atatagctaa gtcagaaaaa aataataatc
     4501 cagttggttc tggtgcattc aagtttaagg aatggaaaaa aggtgaaagc atagtatttg
     4561 aaaagaatgc agattatttt ggtggagaac ctaaggcaga ttctatagcg ctaaaaataa
     4621 ttcctaatga agcatctcaa gaagcagctt taaataatgg cgaaatttca cttatgaaga
     4681 catctgctga aggatatgaa aaggcaaaat caaactcaaa cttacaaact tatacttata
     4741 gtgaagaaag attaaactac attgtattta accaaaatat atcaaacatg gctaacaaag
     4801 aagtaagaca agccttatca tatgccttaa atagaaatga aatgatagaa tcagcatatg
     4861 gaaaagaagg ttctgtacct gctaaatcta tattagttcc agaagcagac ttctatacag
     4921 aagaaggtgt tgaaggatat gaccaagata caaataaggc taaagactta ttggataaaa
     4981 gtggtgttaa aattgataaa ttaaaaatag gttataacac aggtagattt gggcataaaa
     5041 actatgcctt agtagctcaa caagagttga aaaaaattgg tatagaagct gaaatagttc
     5101 cttatgaaag taaggcattc tttaatatac tatttagtaa tagcactgaa tgtgatatgt
     5161 atgtaaatgg ttatgcttgg ggattagaac caaacccata tagaggtatg tttgaaactg
     5221 gtcaatattg caaccaaact aaatattcta atgctgaaat agatgcttta tgggaaaaag
     5281 gatttactga gttaaacaag gaaaaacgta aagaaatata caaacaaata caacaggata
     5341 tatctaagga tgcacctatt tacactatag attatgaaca aaatttaatg gcagctcaaa
     5401 aaaatctaaa aggaataaaa gatgctaaac catctcctgc aatattattt gaagattggt
     5461 ctaaactgta tgtagaataa ttgatgtaaa attttatatt attaattaga aaaggagatg
     5521 tctaaaaata atattgtttt attattttaa aacgagacat ctcttttaat taggagaatt
     5581 tacttatgtt aaaattaata ttgaatagag taaaagtttt aatacctatg ttaatcttaa
     5641 tatctatatt atcatttgga cttttagaat tagctcctgg tgacccagca gatgcatata
     5701 taaatccttt aatgtcttca caggatattg aaaatataag ggttaatatg gggcttgata
     5761 aaccagtata tataagatat ttaaactggt tgaaaaacac tttaagtgga aacttaggta
     5821 tttcttatat aaaccatatg cccgttacag aacaaattat ggaaaaaatg ggaaatacat
     5881 ttattcttat gggtacttct ttgatatttt caatattggt agctatacct cttggaatat
     5941 ttttagctgt aaataaaaat tcaataacta gtaaagtatc atctgttttt aattatatag
     6001 gtgtttctat cccttctttt tggataggta tgatactcat ttcaattttt tcagttaaac
     6061 ttaacatttt cccatcagga ggtatgcata ctattggaaa tgatagtatt ggagatttag
     6121 taaaacattt agttttgcct gtaataactt taggtctata taatactgct atttttacaa
     6181 attatgtaga agctagtgta aatgaacaat taaaaaaaca atatgttatt acagcaagag
     6241 caaaaggatt atcagaaaaa gtcatactat ttaaacatgt cttgaaaaat tcactgacat
     6301 cattggttac aatcctaggc atgagtatac aaaaattagt cactggtgca tttgttacag
     6361 aagtagtttt ctcttggcca ggtatgggaa gattaatgat tgattcaatt ttttcaagag
     6421 attatactgt aattatggca ataactatgt tatcagcact atttttaatt ttaggtaatt
     6481 tagttgctga tatactatac ttattaattg accctaaaat aaaatctagc aaaggaggat
     6541 tctagttgtg tttacaagta tcttaaaaaa attaaaaaaa gataaatcct ttgcttttgc
     6601 atgtattact cttagcataa taatcatatt aattatagct tcttttatat taaatataga
     6661 ctctaatgca attgatacta cttctaaact tcaagaacct agcttaaagc atatctttgg
     6721 tacagacgaa cttggtagag attacttctc tagagctctt tatggtggaa ggatttcact
     6781 tagtgttggt attttatcaa tgcttatctc tgtagtattt ggtactgctg taggtgttat
     6841 tagtggatat attggaggta agctagacca attcttgatg agattagtag atatgcttat
     6901 gagtatacca agtttcttag ttttgattgt attaaatact tatctaacac ctaaagtttc
     6961 cactattata ctaattattg gattcttaag ttggatggaa gtttcaagaa ttgtacgtgg
     7021 cgaaacatta aaaataaagg aaaatgaata ctgtttagct gctaaagcta ctggtatcaa
     7081 gactagaaat atactattaa gacatatagt tttaaactta aaagagacta ttgtagtcgc
     7141 tggttcgtta aatattgcta atgctatctt aactgaatcc gctcttagtt ttttaggtct
     7201 tggaatccaa ttacctcttg catcatgggg taatatgctt caagatgctc aaagacatat
     7261 ttttgacaag ttatatttag ctgtatttcc aggattactt atatttttaa cagtcataag
     7321 tttgactata ataagcaaaa aattttctag taatacttaa caaattttat atagaaaata
     7381 aaaacagtga ttatctaaag atatacactg tttttatttt tcgtttaaaa aatacatatt
     7441 ttgtatatta taactttaaa tactactcta ccatgttatg taaagcctat tattgctctc
     7501 aaacatatag atgaaaaact aatagtttat tgtaataaaa attgatttat ttatttgtta
     7561 ttttaataac atttttaaga gttcttttta ctaaagaaat ctataataaa tttaaataca
     7621 tgttggtcta catggctata acgttctttt ttaggtctac atagtataac tttccatgta
     7681 ataggatgat taaaaggctt ttctataatt ttgctatttt caaaaaaatc atgaactggt
     7741 gatggtaaaa ttgttataaa atcagaattt gtggttgata gcaacaaaaa atcccatgaa
     7801 ccagacatta tatatctttt taacttaaca ttttcatcag taaatttttg cattagctta
     7861 tgatgtatca taaaagtagg attaaatatt gcaagtaatt gctcattcaa atcgttccaa
     7921 tctatcttat ccttcttagc aagtggatga tttatattta aaaatgctgt aagttcatct
     7981 tcttgaagca catgttcagt tactacactt ttatcaattt tatgtggatg taacagtact
     8041 gcataatcta gttcctgcaa gataagcatt ctatttaagt catatgcacc cttctctact
     8101 atatcaaatt ctatatctgg attatttgca actaactgtg caactacatc tgaaaatgct
     8161 attccaagta taagtggagg tattcctatt ctaacttttc ctttaaattg aactgaatct
     8221 tctcttaaat cttccatcat atttttgtat tcatttataa tatgttctgc atttacataa
     8281 aatctttctc ctgctggtgt taacccattt aacctacctt tatacctttc aaataaatat
     8341 acatcttcac tttcttcaaa attttttata atttgactta atgctggttg agatatgtga
     8401 agtgtcttag atgctattga taaattaaaa ccagatttca ctatttcaac aaaatatttc
     8461 aactgtttta tatccatttt aaaccccctt ccccaaaagt ataatttaga ttatattttt
     8521 tcttctaatg atattttata ggaaaatcaa cataatttca ttaatatttt aacaaaatat
     8581 ttttctaaat ctactataaa tttttatcct ataaattttt cttatacact atataaaaaa
     8641 ttagacttag acaaaatgct tttttcgccg taatctataa ttagaaacag gaaaacctaa
     8701 agcattagga ataaaagtaa ttgaaatact taaaaacaag cttgtattaa aaaagtactt
     8761 tattatagtg ttccctaatt tctttattca gaaaattttt aattatcatt caagaaaggt
     8821 aactattaga tatgaaagat gtagtaatcg tatcagcagt cagaacacct ataggaagtt
     8881 ttggaggtgt atttaaaaat acttcagctg ttcaacttgg aactatcgct gttaaagaag
     8941 cgatatcacg tgtaggactt aatttatctg aaatagatga agtaataatt ggaaatgttc
     9001 ttcaaacagg gcttggacag aatgttgcta ggcaaattgc tataaattca ggtataccaa
     9061 attctgttcc aagctacaca gtaaataaat tatgtggttc agggcttaaa agtgttcagc
     9121 tagctgccca atcaatcaca tctggtgaaa atgatgtggt aattgcaggt ggtactgaaa
     9181 atatgagcca agctccttat atcgttccaa ctgctcgctt tggtagtaaa atgggtgaca
     9241 taaccatggt agatagtatg ctaacagatg gccttattga tgctttcaat cagtatcata
     9301 tgggaataac tgcagaaaat attgcaacta aatttgaatt tactagagaa atgcaagata
     9361 aattggcatt agaaagtcaa aataaggctg agaatgctat aaaaaacaac cgctttaaag
     9421 aagaaatcgt tccagtagat gttttaatac gtcgaggaaa aatagaaact attgataaag
     9481 atgaatatcc taaattaggc atgacatttg aaggtttagc taaacttaaa cctgcattca
     9541 aaaaagatgg tactgtaaca gctggaaatg cctcaggtat taatgatggt gcggctatgt
     9601 taatactaat gagccaacaa aaagcagacg aactaggtat tagaccactt gctaaaataa
     9661 aatcctatgc ttcagctggt gttgaacctg aagtcatggg tactggtcca atccctgcaa
     9721 ctagaaaagc actgaaaaaa gctggactta gcatcaatga tatagactta atagaagcaa
     9781 acgaagcgtt tgctgcccaa gcattagctg ttaaaaatga acttcaaata gattcatcaa
     9841 agttaaatgt taatggtggt gcaatagcat taggacatcc aataggagca agtggagcta
     9901 gaatacttgt taccttaatt tatgaaatgc aaaaacgtaa agttgaaact ggacttgcaa
     9961 cactttgtat tggtggtggt caaggaatat caatggtggt ttcacgatag gaggaaatat
    10021 gaataaaata gttagcattg atgaagctct atctcatgta aaagatggag atacaataat
    10081 ggttggtgga ttcatggcca atggttcacc agaaaattta attgattatt tatgtagtaa
    10141 aaatataaaa gatttgacac taatttgcaa tgatactggc tttattgaca aaggagttgg
    10201 caaaatggtt gtaaataagc aatttaaaaa gataattgct tctcatgtag gattaaataa
    10261 agaaactgga agacaaatga acaacaatga aacagatgtt gagttagttc ctcagggaac
    10321 tcttgctgaa caaatacgtg cagctggtta tggtctagga ggtatactca caccgactgg
    10381 tattggtact cttgttgagg agggaaagca aaaaattgtt gtcgatagca aagaatacct
    10441 tcttgaaaaa ccaatttatg cagatgttgc tcttctattt gcatcaaagg tcgataaagc
    10501 aggtaatcta gtttataaag gctctatgaa caattttaat aatttaatgg catctgctgc
    10561 caaaattaca atagttgaag cagatgaaat cgttgaaatt ggtgacattg acccaaatga
    10621 agttaataca ccaggtattt ttgtgaatta catcgttgaa ggaggtaatt tataatggat
    10681 aaattagaaa tgcaagaata tattgcaaat agagtatcta aagaattaaa agacggagcc
    10741 gttgtaaacc ttggaatagg tctaccaacc aaagtagcaa attatattcc ggataatgta
    10801 aacgttatct tacaatctga aaatggcttt ttaggtttag gttcagccga agatggaaat
    10861 tcaagtgatg aaactattgt aaatgcaggt ggtcaaccag ttactatact tcctggagga
    10921 tgtttctttg atagtgctac ttcttttgga ataatcagag gaggtcatgt tgatataact
    10981 attcttggcg cacttcaggt tgacaaatat ggcaatatag caaactatat gattccaggt
    11041 aagatggttc caggtatggg tggagctatg gacctagtaa ctggagctaa aaaagttatt
    11101 gtagcaatgg aacatacttc aaaaggttct gcaaaaatat taaataattg tactcttcca
    11161 cttactgcaa caaatgctgt agatttgata gttactgaaa tgggagttat ggaagtaaca
    11221 tcagatggaa ttttacttaa agaaataaat ccagctttca cattagatga tgttatttct
    11281 gctactgaag ctcctttaat attgtcagat tcattaaatg gaaaaatatc tgttgtttaa
    11341 aataattaaa actagaaaat aaaaatctct tagacgtatt acatataaat ttgtattgct
    11401 taaaatatta atataaaaat aaaataaaat tggaggaaat gaaaatggtt aaagataaag
    11461 ttgtattcgt aacaggagct gcaagtggaa taggtaaaca aatagctgaa tcgttcttaa
    11521 aaaatggtgc taaagtaatg ttctctgata taaatcaaga agctttaaat aataccataa
    11581 cagagttaca aaaaaaaggt tatgattgca tgagtgtaaa gtgtgatgta actaaggaag
    11641 aagaaattaa ccacgctata gataaaactg ttgaaaagta tggcagatta gatatattaa
    11701 taaacaatgc tggacttcaa catgtttcta tgatagaaga tttcccaact gataaatttg
    11761 aatttatgat aaaaataatg ctgacagcac cttttatagc tactaaaaaa gcatttccta
    11821 taatgaaaaa acaaggcttt ggtcgtataa taaatatggc ctcaatcaat ggtgtaatag
    11881 gatttgctgg aaaggctgct tataactcag caaaacatgg acttattgga ctaacaaaag
    11941 ttgctgctct tgaagctgcc gattctggta taacagttaa tgctttatgc cctggatatg
    12001 tagatactcc acttgtcaga ggtcagttta atgacctttc aaaaactcgt aatataccat
    12061 tagaaaatgt cttagaggaa gttttgtacc cacttgtacc acaaaaacgc ctattagatg
    12121 ttcaagaaat tgccgactat gctatgttcc tagcaagtga taatgctaag ggtattacag
    12181 gacaagcttg cttactagat ggaggatata ctgcacaata gttattatat ttagggcttg
    12241 aagaaagtat tcttcaggtc cttctactaa ggagggatat ttatgagtat tatcgcacca
    12301 attggtataa ttattggtat catagctatt atatattttt cagttaaaga aattcatata
    12361 actatagctg ctccaatagc aactttaata gttgttctct taaataaaat ggatgttgta
    12421 acatcaatgc taggtgctga caaaaacaat tatatgggtg cacttggaaa ctatataatg
    12481 agttattttg caatattctt attaggctca atacttgcta aatttatgga agaaagtgga
    12541 gccactgtat caatagctga ttttatttta aataaagttg gctctaatca tccttataga
    12601 gttttagttg ctatatttat agtaagtttt atattaacgt atggtggtat aagcttattt
    12661 gtagttatgt ttgcagtcat tccacttgca agaactctat ttaaaaaact tgatatttct
    12721 tggaacctta ttcagatacc actttggctt ggtattgcaa caattactat gactataatt
    12781 cctggaacac cagccattca aaatgttata cctattcaat atctaaatac gtctcttact
    12841 gcagctacta taccaagtat tgtaggtagt ataggttgtg ctacgtttgg acttgtctat
    12901 atgaaatatg ctctaaacaa aagtattaga aaaggtgaaa cttacgcaac ttacacttca
    12961 aaattagaag aagaatcttt agatagagaa ttaccaggat tttttgcaag tatttttcct
    13021 ctattagcac tcgtaattat agctataact ggaagtactt ttggttcaga atttatgaaa
    13081 aaaaatgtaa tttacatagc tttaatagtt gcaattcttt tatctgcttt tttattccat
    13141 aaatttctat catctaagat acagacattg agcataggtg ctagtggttc tataggtcct
    13201 atatttgcta catcttctgc agttgcattt ggagcagtaa taatggctgc acctggtttt
    13261 gatgtattta gcaaacttat aatgtcaata ccaggtagtc cacttataag tcttactgtt
    13321 ttgacttcaa caatgtcagc aataacaggg tcctcttctg gtgcattagg aatagtaatg
    13381 ccaaactttg cagattatta tttaagtact ggtctaaatc cagaattaat tcaccgtgtt
    13441 gctacaatag cctcaaatat actaactata gttccacaaa gtggtgtttt tcttacattc
    13501 ttaagcttat ctaagttaac acataaaact ggatttaaag aaactttcat tgtagttgca
    13561 gttggttcac taatagcaga aattattgta attacattag gattactaat gtattaatat
    13621 aaaacaaatt aaaattcata atatgaaagg tggtgtctca aagtgaactt tttacttaat
    13681 gagacactct ttttgtatga aatcaaatat attttaatca tttcaacaat aaaaaagaac
    13741 ctttctctat tttgagacaa acccttttta ttccttaaag atttaaacaa ttataatttg
    13801 ttactaatac gaaaacatct attgaataaa tttaaccaaa taaaaaaaaa tttatcataa
    13861 ctataaattt acgttatgga attattataa aaatattatt ttctctaagt aagtaattcc
    13921 atactataca ggcttttaat acaaattttc aaacacactg aaatatacct atttattcca
    13981 tatatatctt ttttacatat ctttacagta aaaaaagtct taatcttatg ttagtataga
    14041 ttcacgggta ccccctacac taaaggttac aaatcagtaa catttttaga atttttagat
    14101 taagaggtgt ttaatgatga gaagaaatat accaacaaaa ttaaaaacta tattagcttt
    14161 aggagtgtta actttagcaa cagcttcaag tgctgttact gcaagtgctt catcacttga
    14221 aaataatgta aatataagta acaaaagttt agtatatagt aatactaaat acaagttttc
    14281 tgcaaaacca aattgttctg taaaaccaga acttaaacct gataaagata actcttgtaa
    14341 ggataagaat cataatgaca agaattgcaa caacactaat aaacctgagg acaacaataa
    14401 ttcagactct actaataagc ctgataacaa taaaccagag tctaataaac ctgaggacaa
    14461 caataattca ggctctacta ataaacctga taacaataaa ccagagtcta ataaacctga
    14521 agacaacaat aactcaggct ctactgataa acctaataac aataaaccag agtctaataa
    14581 acctgaagac aacaataatt cagactctac taacaaacct gatgataata acaactcagg
    14641 ctctacaagt gaaaattttt cagcttacca aaaagaagtt gtcgacttag taaatataga
    14701 aagagctaaa gctggattaa atcctcttac tcttgattct tctatatcaa atgttgctac
    14761 aaaaaaatct caagatatga ttgataacaa ctatttttca cacaattctc caacttatgg
    14821 ttctccattt gacatgttga aaaaatttgg aataagctat aagacagcag gtgaaaatat
    14881 agctatgggt caaaaaactc ctaaagaagt tgtaaacgca tggatgaatt ctgaaggtca
    14941 cagaaaaaat ataatgaatc caaatttcag taaaataggt gttggagtag cacaaaaaag
    15001 tggtggttca atttattgga cacaaatctt tgtaggataa aatactcttt ttccatgcat
    15061 atcaaaagag tatctctaag tgataaaaaa cacaaatgag atactctttt gtatctattt
    15121 taaaattatc aaatccaaat atacatacta taaatattat ttgttctctt aattttagtg
    15181 tgtagaacaa tatataaaaa gtattggcaa gatgaaaatg gaaaacttaa aaagatattt
    15241 aataggtaaa aacaggatct taatatcttc ataaaaaaag gctgtctcaa aatagagata
    15301 aggccttttt cattgttgaa atgattaaaa tatatttgat ttcatacaaa aagagtgcct
    15361 catgaactaa aaagctcact ttgagacact ctcttttatc aattctatat aagcattata
    15421 atactttaat attattcagc taattttttg tatccttcat atctttcttt agcatcagct
    15481 tcagctttag caaataatcc atcagcttcc tctgggaatt gtttagctat agcagaatat
    15541 cttacttgtg caagtatgaa atctttgaag cttgcagttg gttcttttga atctaaagtg
    15601 aatgggtttt taccttcagc ttttacttct ggattgaatc tgtataaatg ccagtatccg
    15661 caagcaacag cttgtgcttc attagccaca gttcttccca taccttcttt taatccatgg
    15721 tttatacatg gagcataagc tattattaga gatggcccat catgtttttc agcttctaaa
    15781 acggctttga taaattgatt tttatcagcc cccatagcaa cttgagctac atatacgttt
    15841 ccatatgtca tagccatcat tcctaaatct ttctttctag attttttacc tgaagcagca
    15901 aacttagcca tagcagcagc tggagtagct ttagaagctt gacctcctgt atttgaatat
    15961 acttctgtat caaatacaag tacgtttaca tcttcaccag atgcaagaac atggtctaat
    16021 ccaccgtaac caatatcata tgcccaaccg tctccaccta gtatccattg agatctctta
    16081 actagataat cttttctatc ttttatagct tttactaatt ctttagcttt ttcatctgta
    16141 caatcacaag ctggtttttc taataattca acaaccttag cacttgctac tttagaagct
    16201 tctccatcat ttctagaatc taaccactct gtaaatactg ctttagcatc ttcacagata
    16261 tccatagaaa ctaactctgt catagcatct actattttat ttcttatttg cttaacagct
    16321 gtgtacatac caaatccata ttcagcatta tcctcgaata aagaatttgc ccaagatgga
    16381 cctttacctt catggttaca agtataagga attgatggtg cagaagctcc ccatatagaa
    16441 gaacatccag tagcattagc tatcatcatt ctatctccat ataattgtgt aactacttta
    16501 atgtacgcag tttctccaca tccagcacat gctcctgaaa actccattaa tggttgtcta
    16561 aattgacttc ctttaacagt atttgcaggc ataacatcaa cttttggagc tacttcatca
    16621 ggatttactg caaatgccca attatctaac tctgtatcaa gttgagtatc tattggcttc
    16681 ataactaaag ctttttcttt agctggacat atgtcagcac agtttccaca tcctgtacag
    16741 tcaagtggac taacttgaat tctatatttt aatccttcta atcctttacc taatgctttt
    16801 ttagcttcaa atccttctgg agcattagct aattcttctt cagtaactaa tactggtctt
    16861 atacatgcat gaggacatat aaaagaacat tggttacatt gaatacagtt atctattatc
    16921 cattcaggaa catcaacagc tataccacgt ttttcataag ctgcagtacc acaagggaat
    16981 gttccatctt ctataccatt gaatgtactt actggtaagt tgtttccttc ttgtgcagtc
    17041 attggtctta gtatattttt tataaattct ggttctttaa cttctccttt atctgcatca
    17101 acagcatttt cccaagaagc tggaacttca actttaacta aagcatttat tcctgcatca
    17161 acagcagcat agttcatatt aactattttt tcaccttttt taccataagc tttaactata
    17221 gaatctttta agtatttaac agcatcttct tctggtatta tttcagctaa tttaaagaat
    17281 gcagattgca ttatcatgtt tattctgttt ccaagaccta tttcttgtcc tagtttaaca
    17341 gcattaactg tatagaattt tatatcattt ttagctatat attgtttcat atgagctggt
    17401 aaatgttctt caagtcctgc ttggtcccat atagtgttaa gtacaaatgt accacctttt
    17461 ttaagacctt ttaataaatc atattgataa acatatgatt gtttatgaca ggcaatataa
    17521 tcagcttcat ctattaaata agtagctctt attggagtat caccaaatct taagtgagac
    17581 atagttatac caccagattt tttagagtca taatcaaagt aagcttgagc atatttttca
    17641 gtatggtcac cgattatttt gatagcttgt ttattagctc caacagtacc gtcagaacct
    17701 aatccccaga acttacatct tatagttcct ttagaagcta tttttattgg ctcagatgga
    17761 gttaaagaag tattagttac atcatcaact atacctactg taaatccatt tttaggttgt
    17821 tctgaaacta agttatcaaa aacagttttt atatctgaag gagtagtatc ttttgaacct
    17881 aatccgtatc ttccacctat tatcatagga gcattttctt ttccatagaa tacatcacgt
    17941 acatctaagt ataatggttc accagttgaa cctggctctt tagttctatc aagtacacat
    18001 attctttcaa cagtagatgg catagcatct aagaaatgtt tcattgagaa tggtctatat
    18061 aaatgaactt taactaaacc atatttttct cccttagcat ttaagtaatc tatagtttct
    18121 tctattgttt ctgttactga acccatagct attaatacgt atttagcatc ttctgctcca
    18181 tagtaatcaa ataaactatg ttttctacct gttaaattac tcattttttc catgtatttt
    18241 tcaactatac ctactatatt ttgatagtat ttattagaag cttctctagt ttggaaatat
    18301 atatctgggt tttgagcagt accacgagca actggatgat ttggagataa agcattatct
    18361 ctaaatgctt gaactgcttc aaagtttaat aaacttgcat aatcttcatt ttctagtaat
    18421 tcaacttttt ggatttcatg tgaagttctg aatccatcaa agaaatgtat aaatggtaat
    18481 ctaccttcta ttgcagctaa atgtgcaaca ggtgctatat cagctacttc ttgaactgaa
    18541 ccagaagcta ataatacaca tccagtttgt ctagcagcca taacgtcttg gtgatcccca
    18601 aatattgata acgcttgaga tgccaaagca cgagcactta catggaatac tcctggtaat
    18661 aactctcctg caactttata catgttaggt atcattaata ataaaccttg agatgctgta
    18721 aaagtagaag ttaaagctcc tccttgtaaa gaaccgtgga atgttcctga tgcacctgct
    18781 tctgactgca tttcaacaac attaactgtt tgtccaaata tattttttct tccttgtgat
    18841 gcccactcat caactacttc agccatagtt gaagatggtg tgattggata tatagctgct
    18901 acatctgtaa acgcataggc aacatgagct gcagctgtat ttccatcaag tgttttcata
    18961 aacttagcca taatatgtat cctccttgat agctacaatt gtacttgttt ataacaagtc
    19021 tattttttta tatttacata taatttacac aacaaaaata taaacacaca tatagtcgcg
    19081 caaatactct atcttctaat ataatactac agattagata aaattccttt gaaaattgta
    19141 aattaattac atatttaagt agattttttt taaaattaaa tatgttaagt ttttttcata
    19201 attttgtata caatatataa taaattaagt tagacttttc aaactt
//
LOCUS       DAMJWO010000080        18843 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.082, whole genome shotgun sequence.
ACCESSION   DAMJWO010000080 DAMJWO010000000
VERSION     DAMJWO010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18843
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.082"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(4..2028)
                     /locus_tag="PC366_002938"
     CDS             complement(4..2028)
                     /locus_tag="PC366_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2578435.1"
                     /translation="MDKKKLILITYDKLNSDHYKEELTNFFGDEIIIETQNILDGIKE
                     NLEGEVVLSLSPLTSNFLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTN
                     KTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
                     RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTID
                     EIGDGLIFFNTFNKVTFVNKSLLNMLELDEKLIKSPSLMEYMPKSFLDKITKNLNIDN
                     MIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKY
                     KFNNIIGNSSIIKDCIKRAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFV
                     AINCASLPSELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQV
                     KLLRVLQEKEIRKIGGTSIIPIDVRILAATNKDLEKLIIENKFRMDLFYRISMFTLDL
                     PPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCVEYMAYM
                     GSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKL
                     MKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSSITEKGIKIIENNII"
     gene            2418..3086
                     /locus_tag="PC366_002939"
     CDS             2418..3086
                     /locus_tag="PC366_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578436.1"
                     /translation="MSKLESTTEKVEVKWYGYVALILGALFFSGIFKDAPGPLKVLDF
                     NNVLGSFGTLGTINDGVGTLASNFRGDGGTGPRDGWLYALTLIPSVMFALGVVRVIDH
                     LDGMKAAQKLLSPLLKPLLGLPGFAGLTLIASLQSTDAAASMTKELKDDGYIDEKQKA
                     VFCAFQFSGASAITNFFASGAALFPFIGDVPIFIPLALILIMKFVGANLLRLYLNKFD
                     KGEA"
     gene            3088..3573
                     /locus_tag="PC366_002940"
     CDS             3088..3573
                     /locus_tag="PC366_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HDF2578437.1"
                     /translation="MSEVAKKEVKVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVAATAIMTIFISMGGASGVIAGLFTAGQI
                     SQAHVAILLPMLLLSGAQIQFMGRLLGTAELKTKYYPHMFVIATLNGCIAMLIMNYFV
                     V"
     gene            3634..4755
                     /locus_tag="PC366_002941"
     CDS             3634..4755
                     /locus_tag="PC366_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HDF2578438.1"
                     /translation="MGTNKDYIEYVHKVYDYLHTIPEKGFEEYKTSEFVLKELEKMGF
                     ENINKGVAGTGIIVTIDSKKEGPVFAIRADMDALEFIIDGEKKMIHACGHDGHTSMLL
                     TAAKLIKERNLVKRGKLKILFQPGEEKLYGALRVIDSGLLDDVEEMVGMHLRPGQDCR
                     LGKAIPAMYHCASCIMQFTIKGITCHGSKPHLGVNAVDAVCLAVNAINAIRVNPAIPN
                     SIKVTNISVKGETYNNIPDEAFMALDIRAESNDIIEELKEKAIHAVKTAVSSINAEAV
                     LISKDGVPAAEFDEELVNLAEETIKDVLGADASIGIFKNSGGEDFHYYTQKLKCKTTY
                     IGLGADATPGFHNPNVTFDTKALEYGVDIWCRLVEKRLG"
     gene            5036..6226
                     /locus_tag="PC366_002942"
     CDS             5036..6226
                     /locus_tag="PC366_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2578439.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQKDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEINRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIVQKPVYYPFEAKIKSNNRDIVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLVRKGFKH
                     TPLQSLCPEYKDKIITCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNESEDWLNELNDYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMDRLKTI
                     FENL"
     misc_binding    6360..6615
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6674..7675
                     /locus_tag="PC366_002943"
     CDS             6674..7675
                     /locus_tag="PC366_002943"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HDF2578440.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEGIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     gene            7779..8168
                     /locus_tag="PC366_002944"
     CDS             7779..8168
                     /locus_tag="PC366_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HDF2578441.1"
                     /translation="MEFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIVDKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDAIVLIWSIGIVNEEIN
                     KYRVIIKKDKHSNIIENVEFSIKDEEE"
     gene            8329..9537
                     /locus_tag="PC366_002945"
     CDS             8329..9537
                     /locus_tag="PC366_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HDF2578442.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFAVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGNKEEQSA"
     gene            complement(9624..10700)
                     /locus_tag="PC366_002946"
     CDS             complement(9624..10700)
                     /locus_tag="PC366_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDF2578443.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSIDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSIEKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTDTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNLDLWNINIIASKMGEIMFSDLDFISNTISLMNTERDY
                     LLKELKNIKSLDIYNTKGNFILCKIKTKELTAKSLREQLLPQKIIIRDCCSFEGLDEY
                     FFRVCILKPNENKLLISSLKAIFK"
     gene            10929..11456
                     /gene="hpt"
                     /locus_tag="PC366_002947"
     CDS             10929..11456
                     /gene="hpt"
                     /locus_tag="PC366_002947"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDF2578444.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            11545..12477
                     /locus_tag="PC366_002948"
     CDS             11545..12477
                     /locus_tag="PC366_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HDF2578445.1"
                     /translation="MDIQLNILLFFQNLRNPILNFIFLVFTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYLHLIGAVMVLGVGLSRLYLAVHWPIDVIVGWMLGIFFTVIF
                     IKIFDYIDDNKNYILLVVLLIPFIIVAIFLNSPEYFEKFGIIVGFVFGYMVEDRFVKF
                     NTDNNNKKINFSNKNKGSKNIIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNISD
                     STMSIIFMNFIKNTVVVFYGIAGAPALFKLLKLN"
     gene            12539..13765
                     /locus_tag="PC366_002949"
     CDS             12539..13765
                     /locus_tag="PC366_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2578446.1"
                     /translation="MKKVVIIGGGPAGMIAASTACEKGYDVTLIEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNDDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNDKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIIDTKPSLIGIEVQESFTKDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTRFGLDGPIIKSASCRMKDTRKENYTILLDLKPALDEEKL
                     DKRVQKDFQKYTNKKFEKALDDLLPKKLIPIIINLSEINANTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIEEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            13849..14070
                     /locus_tag="PC366_002950"
     CDS             13849..14070
                     /locus_tag="PC366_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HDF2578447.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            14259..14429
                     /locus_tag="PC366_002951"
     CDS             14259..14429
                     /locus_tag="PC366_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578448.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
     gene            complement(14522..14983)
                     /locus_tag="PC366_002952"
     CDS             complement(14522..14983)
                     /locus_tag="PC366_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578449.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILRKYQKGITSGKLTADKFADNIL
                     SQHFISSILNEKIVNETNFKISYRNYIETLINIQNENLSNLRKKSTKTAKCFNISQIT
                     QLKNLLSNTGYNLLIPYKYLTARDIEGIVTLINTGSIELGNERIYNYISKA"
     gene            15166..15633
                     /locus_tag="PC366_002953"
     CDS             15166..15633
                     /locus_tag="PC366_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578450.1"
                     /translation="MKMLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKI
                     DSVFFKLLKLAFGSILLMIAFNLNMILGIGVFLIGVVYILYKRNMEEQVKEHINNVKN
                     NIDISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            15676..17439
                     /locus_tag="PC366_002954"
     CDS             15676..17439
                     /locus_tag="PC366_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HDF2578451.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYITEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDTIVSCYNVEQKKKTNLYPMIDMFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNETIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYATKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMKDATYE
                     NNTLSMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            17447..18055
                     /locus_tag="PC366_002955"
     CDS             17447..18055
                     /locus_tag="PC366_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2578452.1"
                     /translation="MDSNDKKGLKSTEIIIINGSPRINKNCSFIANKVKAMLEECGLS
                     CKIFNIYNMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYVLNKPSIDRNKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNNTDDVSYIDNQEFKDIIYKNLKIYIDSI"
     gene            18127..18696
                     /locus_tag="PC366_002956"
     CDS             18127..18696
                     /locus_tag="PC366_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HDF2578453.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
BASE COUNT         7212 a         1991 c         3193 g         6447 t
ORIGIN      
        1 ggtttaaatt atattatttt ctattatttt tatgcctttc tcagttattg atgagccttt
       61 tcttccttta ctagaaatta agtatccatt gcgtgtcaaa tattctagca tatttcttac
      121 ttcgtattct gtgacattat attccataaa tttcattaac tttgtcctcc ccattggttt
      181 catgtgcaat gattttagga tagaaatgca tatgtttttg tcatattggt ttaaatcatt
      241 gaatatagac atattacttg acatatgatt attatttaat tttgaagata tgttttgagg
      301 taaatcattt attgtaagat aattggaacc catgtaagcc atatattcaa cacaatttct
      361 cagttctcta atattcccca tccaagtgta tgaatttaaa gcttctaaaa gactcttatc
      421 gagttttatg tttttatagg gaagttcttt taaaaatgat tctaaaagaa gaggtatatc
      481 ttctaatctc tttctaagag gaggtaaatc taaagtgaac atacttatcc tataaaataa
      541 atccatccta aatttatttt ctataattaa tttttctaaa tctttatttg tggcagctaa
      601 tattctcaca tcaattggaa taatacttgt accaccaatt tttctaattt ctttttcttg
      661 taagactctt aaaagtttaa cctgtaaatc atgtggcata tctcctatct catctaaaaa
      721 tatagtgcca gtatgagcta attcgaataa tccttttttt ccaccttttt ttgctccagt
      781 aaaagaacca tcttcatatc caaatagttc actttcaagt aattcacttg gtaatgaagc
      841 acaatttatt gctacaaaag gtttattttt tctatttgaa tgattgtgta ttgactgagt
      901 aaaggcttct ttacctgttc ctgtttcacc tgttattaat ataggattat ctgtaagagc
      961 catttttttt gcccttttaa tacaatcttt tataatagaa ctatttccaa taatattatt
     1021 aaatttatat ttagctacat aacctctttt gacagaatca cttcttattt tttgttctaa
     1081 tatttctata ttgtttacat cttttaatgt aattaagcaa ccctctatat ttttataaag
     1141 ataaaatggt tttttagaaa gtatgaattt tttatctatt tcgtctatgt atataatcat
     1201 attatcgata tttaagttct ttgtaatttt atctaagaaa ctctttggca tatattccat
     1261 taaggaaggt gattttataa gtttttcatc tagttccaac atattaagta aagacttatt
     1321 tacaaaagta accttgttaa aggtgttgaa aaatattaga ccatcaccta tttcatcaat
     1381 ggtcatgtaa agtatagttt ttaatttaga tatattatct aatgacgtat ttaagaaatc
     1441 atgacttagt gtctccttgg acaatttgta tagtttttct ataaatttct cattttttag
     1501 ttttaatact actaataatg acatatatgt atctaatgag atttttctcc aacctaaatc
     1561 aacaatattt tttatgtatt ttggtataaa tctaatctga cctggtgtta tagctgtatc
     1621 taaatcatat atttcatcac aatctggata tgtcggtaca aaatctatat gatttatacc
     1681 aattttatat agataagtag ccatctcaaa tgctgaagtt ttattggttg tcataagtaa
     1741 cgattttgta cctggaggta gtttcatcat tttttcatat ccaagttttg aaagtgcttt
     1801 cgttccatga ataatttcaa tatcttcctt aaaatgtttt attaaaaaat tactagttaa
     1861 aggtgataga gaaagcacta cctctccctc taaattttct tttattccat caagtatatt
     1921 ttgtgtttct atgattattt cgtctccaaa aaagtttgtt aattcttctt tgtagtggtc
     1981 actatttaat ttatcatatg ttataaggat taacttcttt ttatccattt tatttctcct
     2041 aacaaaatag tatttatttt taaagtattt aaagtataag gtaagttata ttatacaaca
     2101 aatagtagta taaatttata tatttgatta aataataggt ttttttagga ttttatccta
     2161 taaaaaccta ttttaaaatt atttttgcaa gataaggaaa atagcttttt atattgtaat
     2221 gtatatttta aatagttaat aaaaaaatat tatattttta aacttgaaaa gtaagtaatt
     2281 ataagctatt taatcgctgg aataaattta caataaaaaa ataaatacaa aggctttatc
     2341 attaaggtat tggcataagt tttgcttatt aaacaagtat actaataaaa ttcatttaaa
     2401 caggagggag aatttatatg agtaaattag aatcaacaac agaaaaagtt gaggtaaaat
     2461 ggtatgggta tgtagcatta atattgggag cattattttt ttcaggaata tttaaagatg
     2521 caccaggacc attaaaagta ttggatttta acaatgtatt aggttctttt ggaacattgg
     2581 gaacaattaa tgatggtgta ggtacattag cttcaaactt tagaggtgat ggaggtactg
     2641 gccctcgaga tggatggcta tatgcattga cattaatacc atcagttatg tttgcacttg
     2701 gagtagttag agttatagac cacttagatg gaatgaaggc agctcaaaag cttcttagtc
     2761 cactattaaa gccattatta gggttacctg gatttgcagg actaactttg atagctagtt
     2821 tacagtctac agatgcagct gcatctatga ctaaagaact taaagatgat gggtatatag
     2881 atgaaaaaca aaaagctgta ttttgtgcat ttcaattttc aggtgcgtct gcaattacga
     2941 atttctttgc ttctggagca gcactatttc catttatagg agatgtacca atatttatac
     3001 cacttgcttt aatattaatt atgaagtttg ttggggcgaa cttacttaga ttatatttaa
     3061 ataaatttga caagggggaa gcttaacatg agtgaggtag caaaaaaaga agtaaaagtt
     3121 aaaaaaggaa atgtgataga tgcgtttatt ggaggagcta gaaatggatt ccaaataagt
     3181 acaaattcaa tggctccaaa tgtcatcttc ggttttgcta taatttctgt gttcaattta
     3241 acaggtcttt tggatgtaat agggacaata tttacacctg taatgagtat ctttggactt
     3301 ccaggtgttg cagcaacagc tataatgaca atatttatat caatgggagg agcatctgga
     3361 gtaatcgcag gtttatttac agcaggtcaa ataagtcaag cacatgttgc aattctattg
     3421 ccaatgttat tgctttcagg agcgcagata caatttatgg ggagactttt gggaacagct
     3481 gagttaaaaa ctaaatatta tccacatatg tttgttatag caactttaaa tggttgtatt
     3541 gcaatgctta taatgaatta tttcgtagta taggtaatta taataaaaat ttaatataaa
     3601 tggaaagttt aaattttaag gaggagctag attatgggaa ctaacaaaga ttatattgag
     3661 tatgtacata aagtgtatga ttatctacac actataccag aaaaaggatt tgaagaatat
     3721 aagacatcag agtttgtttt aaaagagctt gaaaaaatgg ggtttgaaaa tattaataaa
     3781 ggagttgcag gaactggtat tatagtaact atagattcta aaaaagaagg accagtattt
     3841 gctataagag cagatatgga tgcattggaa tttatcatag atggagaaaa gaaaatgata
     3901 catgcttgtg gtcatgatgg tcatacttct atgcttttaa cagctgcaaa gttaataaaa
     3961 gagagaaatt tagtaaaaag aggtaagtta aaaatacttt ttcaaccagg tgaagaaaaa
     4021 ttatatggag cattaagagt aattgattct ggtttgttgg atgatgtaga agaaatggta
     4081 gggatgcatt taagacctgg acaagattgt aggttgggaa aggcgatacc tgcaatgtac
     4141 cattgtgcta gctgtataat gcaatttacg attaaaggta tcacttgtca tggttctaaa
     4201 ccacatttag gagtaaatgc agtagatgct gtctgtttag cagtgaatgc aataaatgca
     4261 ataagagtaa atccagctat accaaattct ataaaagtaa caaatatatc agttaaggga
     4321 gaaacttata ataatatacc agatgaagca tttatggctt tagatataag ggcagaaagt
     4381 aatgatataa tagaagaatt aaaagaaaaa gcaatacatg ctgtaaaaac tgctgtaagt
     4441 tctataaatg cagaagctgt actaatttcc aaagatggag taccagcagc agaatttgat
     4501 gaagaacttg taaacttggc tgaagaaact ataaaagatg tattgggagc tgatgcatct
     4561 ataggtatat ttaaaaattc tggtggagaa gatttccatt attatacaca aaaactaaaa
     4621 tgtaaaacta catatattgg attaggagct gatgctacac caggatttca taatccaaat
     4681 gtaacatttg atacgaaagc tttagaatat ggtgtagata tatggtgtag attggttgaa
     4741 aagagattgg gataatatcc aaactaataa ttctacattt aaaattataa ttatagaagt
     4801 tatagaaaaa gattgcttat gttaattaga aaataattaa tatgagcaat cttattttga
     4861 tataatgaaa ctgattttgg aatattgaaa aaatatgatg gaaaagtaat tatattttaa
     4921 atctattgga caaaaaagtg atattattat aatattaaga attgtaaaat aataccaaag
     4981 tgcatctagt aatggactta acaattataa aaattttatt cttaggaggg aaaaaatgag
     5041 taagtataat tttgacagag taatagatag agtaggaaca gattgtgtaa aatgggattt
     5101 tagaactaat tgttcaacaa aagcacaaaa agatggtttg cctttttgga ttgctgatat
     5161 ggattttgaa tgtgcagaac caataataga agcattacgt aaaaaagttg aacataaaat
     5221 atttggatat agttcaaatg atagtgataa atactttaat gcagtttgtg attggtataa
     5281 aaggagattt aactgggaaa taaatagaaa agatattatt tttagtcctg gtgttgtacc
     5341 tgctgttgct attttagtaa gaatattaac taattctaat gaaggtgtaa tagtccaaaa
     5401 accagtgtat tacccatttg aagctaagat aaagagcaat aatagggaca ttgtaaacaa
     5461 tcctctaata tatgagaatg gtacttatag gatggattat gatgatttag aagaaaaagc
     5521 taagtgtagc aacaataaag tactgatact ttgtagtcct cacaaccctg ttggaagagt
     5581 ttggagagaa gatgaattaa agaaggttgt agaaatatgt aaaaaatatg acctatggat
     5641 aatagctgat gagatacatt ctgatttagt tagaaaagga tttaaacata ctcctttaca
     5701 gtcattatgc ccagagtaca aggataaaat aattacatgt atagctccaa gtaaaacatt
     5761 taatctggca ggaatgcagt tgtctaatat aatagtgaat aatgatgaac taaaaaagaa
     5821 atatcaagaa gaggttacag ctgttggagt tgcaacttca ccaaatccct ttgctattgt
     5881 agctacaata gcagcatata atgaaagtga agactggctt aatgaattaa atgattactt
     5941 agataataat atacaattta ttgatgaata cttaaaagaa aacctaccaa aagtaaaact
     6001 tgtttatcca gaaggaacat atctagcatg gttagatttt actgcttatg gattaaatga
     6061 agtagaactt gaggatttaa tgtttaaaaa agctaatgta ttatttgatg aaggttatat
     6121 atttggaaaa gaaggaatag gatttgaaag aataaatgta gcttgtccac agtctttatt
     6181 aaaagaatgt atggacagat taaagactat atttgaaaat ttataaagta taggtaaaaa
     6241 tttataaagt gtttaaaaat aaaaaaataa taaacttgac aaattttaac taatcactta
     6301 tcatactatt atgaataaat agaaaacata agagagctaa attttattga attaaactct
     6361 taaagacttt gaaaggaaga gtagttatag aatgtaatta aagcgagttg gtgatggtgt
     6421 gagaccaata tgaagtctat aatgaagaac atcctggagt tgctaaccga aattttaaaa
     6481 gagtaggctt agtcggaacc aaaccgttat catattgggg tgtatcgagt aatatctgta
     6541 cattgtgagc tgggtttgaa tttatttcaa actaatcagg gtggtaccgc ggaaaagcaa
     6601 cctttcgtcc cttttatata gggatgaagg gtttttttaa tggaaaaata tataaatata
     6661 gggagtgaat gatatgagca caataatacc aaaggattat aaaagtagtt tgaacgtaat
     6721 tgatacacaa atagctataa aaaaattaaa agattttttt gaaatgagac taagtaatga
     6781 attaaatctt ataagagttt cttctccgtt atttgtattg ccagaaacag gtgcaaatga
     6841 taatttaaat ggagaaaagg ctgtaagctt tgatatacca tttatgaata aaaatgcaga
     6901 aattgttcaa tcacttgcaa aatggaaaag attagccctt aaaaaatatg ggtttgaagt
     6961 tggtagtggt ttatatacag atatgaatgc aataagaaaa aatgaagaat tagacaatat
     7021 acattctctt tatgtagacc aatgggattg ggaattggtt atagataaaa gtagtagaaa
     7081 tgaaaagact ctaaaagatg ttgtaaaaag attgtatgga gtatttaaag atactgaaat
     7141 ttttgtatgt agtatgtatg aaggtataaa agaaatatta ccagaagaaa taacttttat
     7201 aacatcacaa gagttagaag atatgtatcc agaattatca ccgaaggaaa gagaagataa
     7261 aattgtaaaa gagaagaaag cagtatttat aactcaaata ggaaaaacat taatatcagg
     7321 agaaaaacat gatggaagaa gccctgatta tgatgattgg gaattgaatg gggatatatt
     7381 attttacaat cctgttttag attcagcatt agaattatct tcaatgggaa ttagagttga
     7441 tgaagaatct cttgatagac aattgaaact tgctggatgt gaagagagaa aagagtttga
     7501 ctatcataag atgcttttaa atggcgaact tccgtataca attggtggag gaattggtca
     7561 gtcaagaata tgtatgtatt tcttacaaaa agctcatata ggagaagtac aagttggagt
     7621 atggccacag gatatgattc aaaattgtag tagtgcagga attgaattat tataatttaa
     7681 atataaacta attgataaaa tttatatcta atatgttcat caaattaatt atatcggtta
     7741 taatgtagaa taacctataa ttataagagg tgataaatat ggagttttta aaaataatca
     7801 ttaatatagt tttagatatt ttaaaaaaaa ttttggtcag atttaaaaat gctaaatttg
     7861 gtttggtttt tgtatttgat ttacttaaac tacctgattt tatgacagat aaaagaatca
     7921 atatagttga taaaataaag gtaatttctg tattaatttt tactatatcc tactttgtat
     7981 ctggggttga tataattcca gagatgattg caggggcatt tggttttata gatgatgcta
     8041 tagttttaat ttggagtata ggtatagtga atgaagaaat taataagtat agagttatta
     8101 taaaaaaaga taaacattca aatataattg aaaatgtaga attttctata aaagatgaag
     8161 aagaataaca atttatatat gttattcttt tttttattaa caaaaaatgg ttaaattgtt
     8221 gacggagagg taaaactcta ttatcataat aagtggatat ccaatattta actaagtatt
     8281 caatgtgcaa gaatgcttaa tttaaaaaag ttatggaggg taaatattat gaagaaaaaa
     8341 ataggtttag tgcccaaact aatcatcggt atcatagtcg gtattttaat cggaagttat
     8401 gcaccagaaa taatagtaca aatattagta acagttagta ccttattctc agcattccta
     8461 aaatttgtta taccatttat aattataggt tttgtaacag caggtatagc tgatttagca
     8521 acaggtgcag gaaagttatt ggggataact acgggaatag catatggttc taccttaata
     8581 gcaggattat tatcatttgc agtatctaca ttaatcttcc caaattttat tgatgcaagt
     8641 gttgcaagtc aaattggaga cccagaggca ggaatgttag ctccaatatt cacaattcca
     8701 ttagagccta tggtagatgt aacagctgca atcgtatttg catttgtaat gggacttgga
     8761 atatcagctt taagaaatca tggaaaagga gagactttat ttaatttctt ccaagaattt
     8821 caaggaatcg taacgaaaac gttgtcaaca gtgattatac ctttattacc tttatacata
     8881 gcaggaactt ttgcaaatat aactatagca ggggaagtat ggacaatatt aggggtattc
     8941 tggaaagtat acttagtagt aataccttta cattttgtat atatggcatg tcaattcaca
     9001 gcagcaggtg tattttcagg aaaaaatcca gtaagaatgt taaaaaatca agtacctgga
     9061 tatttaacag ctataggaac tcaatcttca gcagcaacta taccagttaa tgttggttgt
     9121 gcagaaaaaa atggagtaag taagcaaata agagaatttg ttgtacctct ttgtgcaaca
     9181 atacatttat caggtagtat gatatcaata acaggattta caactgcagt tttaatgatg
     9241 aatggtatgc cacatggaat aggtgtatta ttcccttata ttgcaatgtt aggtatagca
     9301 atggttgcag caccaggagc accaggtggg gctataatga gtgcacttcc tttcctacca
     9361 atggttggaa taccatcaga tggtgggctt gcaagtttaa tgatagcttt atacttaact
     9421 caagacagtt ttggtacagc atgtaatgta tcaggagata atgcaatagc agtagtagta
     9481 gataaaataa atgatggaat gagtaaaaaa ggaaacaaag aagagcaaag tgcttagttt
     9541 tttaataatc aaaaatgagt tatctcaaat agagatagct cattttttat ggtataaaaa
     9601 aattataaaa taaagggatt tttttattta aaaattgctt taagagatga tattaataat
     9661 ttattttcat taggttttaa tatacatact ctaaagaaat actcatctag accttcaaat
     9721 gaacaacaat ctcttattat tattttttgt ggaagcagtt gttctcgaag cgatttagca
     9781 gttaattcct ttgttttgat tttacacaat atgaaattac ctttagtatt gtatatatct
     9841 aagcttttta tattcttaag ctctttaagc aggtaatctc tttcagtgtt cattaaggaa
     9901 atagtatttg atataaaatc taaatcacta aacatgattt cccccatttt agaagctatt
     9961 atgtttatat tccataaatc tagattttta tttatttcat ttttgacatt agtgttagat
    10021 ataagaccat atccaagcct tattccaggc gttgaaaaaa attttgatgt acctcttata
    10081 acgaataaat tagaataatc atcaactaat tgagtacaag agtatgtatc tgtatcagta
    10141 aactctacat aagtctcatc aatcattaaa aatgagtctg tattttttaa aatttctctc
    10201 acttctactt tagtaaatgc aaatccagtt ggattactag gattacagat tactaccaaa
    10261 tcataatctt tagcattgat agtttttata agattttcta aatttatatg aaaattatct
    10321 tcttcttttg caaagtattt ttctatagaa caattaattt tagataactc tttttcatac
    10381 tctgaatagg ctggagagag taaaagagcc tgtttaggat taattgtatg tataaatgat
    10441 gaaattagtt ctgtagctcc actgccaagt actatattat ctatagaaca tttgcagtaa
    10501 ttggatatag aagtttttaa gtctatgtaa tcagggtcag gatacataga taccatatct
    10561 atattgttta caatgtattg tttggctaaa cttgatgtac caaaaggatt tatatttgag
    10621 ctaaaatcca taaattcttc ctttgaaaag ccatacttac tagataaact atataaatta
    10681 gctccatgat ttgtgctcat aaaagtacct ccaaaaataa aattatataa tcgataaaaa
    10741 taactgatta atatatgtac atatagatta taatacaaag gaatcgttat tccaaatttt
    10801 taatggaaaa agcaaaaaag tatggataag ctgttaattt aggtctaaaa atgatgaaaa
    10861 agattttaat tgatattttg gtatgctata atatataagt taatagaagg aaagcgggag
    10921 gatacaaaat gtacaaagtt acaggaaaaa tgttgacaga agaacaaata aaagaaaaag
    10981 tttatgaatt aggaaaaaag atagaagaag actttaaagg cgaagattta ctagtggtag
    11041 gtatacttaa aggagctagt gtatttgttt cagatttaat aagatgtata gatttggatg
    11101 taaatataga ttttatgagt gttacaagtt atggaaactc aacagagtct tctggaacag
    11161 ttaaaatatt aaaagattta gatgtagata ttgaaggaaa gaatgtgttg attgtagagg
    11221 atataataga ttctggttta acattaagta atctagttgc agctttaaaa actagaaatc
    11281 caaaatcttt aaaactatgt actctacttg acaaacctca gagaagaaaa gctaatatac
    11341 ctgtagacta tgttggattt gttatagaag acaaatttat tgttggttat ggaatagact
    11401 atgctgaaaa gtatagaaat ttaccttata taggtatagt tgaggatgta gaatagattt
    11461 aaatgtgaat caaaagcact aatttctaag ggagttagtg ctttttagtt aattatataa
    11521 aattttagta aaggagacat ctatatggat attcagttaa atatattatt atttttccaa
    11581 aatttaagaa atccaatttt gaactttata tttcttgtct ttacaataag cacagaagca
    11641 ccgttattaa tattaattac aacaattata tactggtgta taaataaaaa atgtggacag
    11701 aaaatactgt ttgctataat tggaaatttt gttgtaaatt taggcatcaa agagtttgta
    11761 aaagctccca gaccaatagg aataaaaggt cttgaatcat tgagagtttc tactgctggt
    11821 ggttattctt ttccaagtgc tcatactcaa actgcaacaa cattttgggt tagtattatg
    11881 actatattta aaaagagata tcttcattta ataggtgcag ttatggtttt aggagtagga
    11941 ttgtctaggc tgtatttagc tgttcattgg ccaatagatg tgatagtggg ttggatgtta
    12001 ggaatatttt ttacagttat atttataaaa atatttgact atattgatga taataaaaat
    12061 tatattttac ttgtagtttt acttatacca tttataatag tagctatatt tctaaatagc
    12121 cctgaatatt ttgaaaaatt tggtataata gtaggatttg tatttggata tatggttgag
    12181 gatagatttg ttaaatttaa tacagataat aataacaaaa aaataaattt tagcaataaa
    12241 aataagggga gtaaaaatat aattttttca agaatatgta ggtttttggt tgggatagta
    12301 acaataggaa tgttatatat tggcattaag ttgtttattt caatgttaat agtcacttta
    12361 aatataagtg actctactat gagtataatt tttatgaatt ttattaagaa tacagtagtt
    12421 gttttttatg gaatagcagg agctccagca ttatttaaac ttttaaaatt aaattgattt
    12481 taaggtatag agtcaatagt ttaaattaaa aaaattaagg gtagaaaaga gtgattattt
    12541 gaagaaggta gtaataatag gtggtggacc agcagggatg atagccgcat caactgcatg
    12601 tgagaaaggc tatgatgtaa cattaattga gaaaaatcat aaattaggaa aaaaacttgc
    12661 aataacagga aaaggtagat gtaatattac taacgcttgt gaaatagagg aattaataga
    12721 aaatgtacct acaaatggaa aatttcttta tagtgctttt tatactttta caaatgatga
    12781 tgtaataagt atgtttaata atcttggagt aaagactaaa acagaaagag gaaaaagggt
    12841 ttttccagag agtgataaag cctttgatat tgtaaatgct cttgaaagac aacttaaaag
    12901 taagaaagta aatatattat taaattcaaa agtagaaaaa ataatatcta aaaataataa
    12961 aattgagaaa gtaattttaa acgataaaaa agaaattaag tgtgattcag ttgtagtagc
    13021 aactggtgga ttaagttatc cacttactgg ttctactggt gatggatata aatttgcaat
    13081 ttcacagggg cacacaatta tagatacaaa accatcttta attggtatag aagtacaaga
    13141 aagttttaca aaagatttag aaaaattatc attgagaaat gttgaaataa gggtgtttaa
    13201 tagcaaacaa aagaaagttt atagtgattt tggagaactt gaatttacta gatttggttt
    13261 agatggacct ataatcaagt ctgcaagttg tagaatgaaa gatacaagga aagaaaatta
    13321 cactatatta ttagatttaa aacctgcatt agatgaggaa aaactggata aaagagttca
    13381 aaaagatttt cagaagtata caaataaaaa atttgaaaaa gcattagatg atttacttcc
    13441 aaaaaaacta atacctataa taataaactt aagtgaaatt aatgcaaata cggttgttca
    13501 ccaaatttct agagagcaga gaaaaaactt agtccattta ttaaaaaatt taaagtttac
    13561 agtaaagaga tacagaccta ttgaagaagc tataataact tctggtggtg taaaagtaaa
    13621 cgaaataaat tcaagcacaa tggaatcaaa attagtagaa ggtttatttt ttgctggaga
    13681 agtaatagat atagatgcat atacaggtgg attcaatttg caaatagctt tttctactgg
    13741 atatttggca ggttttaatt gctaaaaatt acctgaatta aaaatgttta aaatcacata
    13801 atattatcag caacacaaaa taaattaaac agaaggaagg taatcaacat ggcaagtaac
    13861 aataacaaca acagaacagt agtaccagga gcaaaagagg ctttaaacca aatgaaatta
    13921 gaaatagcta atgaacttgg tatgagtaat tatcaacaag ttgataaagg aaaccttact
    13981 gcaagagaaa atggttatgt aggtggatac atgactaaaa aattagttga aatggctgaa
    14041 caacaaatgg ctggaaaaag caacagatag ttataaataa ttatttataa ctattggcta
    14101 ttagtttagc tagagctatc tcaaatatag aaagtaattt ctaaattgag atagcttttt
    14161 tttattaaat tattaaatag atatattttt atgtaataaa ttttatgtat ttggataaaa
    14221 taatacaaat gaatatgtta cataaggagt gatgtaaaat gagtagtgta aattttgagg
    14281 atttaaaaaa caaatttatt aatagtgact tagatgaaaa aataagaata tatacaacaa
    14341 cagaaggttt atcagtagaa caatttaaag agctactaaa atattatcca atacaacatt
    14401 tatctaaact agaaaaagca cttggatagc agtatttagt ccaaaattaa aaaggcaatt
    14461 tatttaatat taaaaatatt ttttattaaa taaattgcct ttttataata ggtttaaatt
    14521 attatgcttt tgatatataa ttatagattc tctcatttcc aagttcaata gacccagtat
    14581 taataagagt aacgattcct tctatatctc tagcagttaa gtatttatat ggaattaata
    14641 aattataacc agtattactt agtaagtttt ttaattgggt tatttgagag atattgaaac
    14701 attttgcagt tttagtagat ttttttctta agttagataa attttcattt tgaatattta
    14761 ttaaagtttc tatatagttt ctataagata tcttaaaatt tgtctcattg actatttttt
    14821 cattaagtat actactgata aaatgttgag acaatatatt atctgcaaat ttatctgctg
    14881 ttaattttcc agatgttatg cctttttgat attttctaag aattttttta gtatagcagt
    14941 atattttatt tctcgtttct aaatcgagtt gttctatttg cacaaaacca cttccttcta
    15001 attataaaaa tatttattaa aaatctatac ttaactaata aagcttcaat aatttattta
    15061 cagtaaatac taaatcataa aatatttgtt attttttatt attaccaagt ataaaaaata
    15121 ttataattgt aaaacttaca aatatatgta aaatatttag gagtgatgaa aatgttaaat
    15181 gggataataa agctttttta ttctgaaatt gtaaaaacaa agattaataa cctagactca
    15241 agtggatatt ctttaagaga tgaatgtaaa gaaatcagaa atataactct aaagatagat
    15301 agcgtatttt ttaagctttt aaagttggct tttggttcaa tactgcttat gatagctttt
    15361 aatttaaaca tgattctagg tataggagtg tttttaattg gtgtagttta tatactatat
    15421 aaaagaaata tggaagaaca agtaaaagag catataaata atgtgaaaaa taatatcgac
    15481 atctctaaaa taacttttat ggatgaaaaa gggagaacag gtctaaatgc attgattaca
    15541 ttacttctta taggattatt gacaggattt aactggatat tagttgctag ttttgtcgtt
    15601 gtttttgttt ttactataaa gaatgtatgt taaaatacta ataaatagtt taatatatag
    15661 ggggagaaat tgagtatgac taatggcagt tataaaatga agaatttagt ggagatatcc
    15721 gctatggtga cggaatctac agattttttt aatataaaag atgacataat agaaaaaatg
    15781 ttagaagttg ttcaccctac aaaggcatgt gtaaatctat tttataaaaa tgattctaaa
    15841 tatgcctact tagtatgttc gcaaacctta gaatatgtac ctcaaatttt tccaataaat
    15901 agtcttaaag gtgcaaaaat tgattttgac acatatccag agtatataca tgaggctgta
    15961 aatgaaaaaa agataatata tgtggaaaat gtatttgaag attctagagc agaaggtgaa
    16021 cgagatttag caaaagctga aggttatatt gggagaatag tttttccttt tataataaat
    16081 aatgtagttg ttggatttat gacttgtttt ttaaaagagg atgattatat aacagaacaa
    16141 gatatagatt ttatatcatc tgttgcatca ctcttaagtt tatcaataga aataactaat
    16201 aaaaataata atgtacaaat tttaattgat aaactaagag gctcaataag tgccataaat
    16261 gaagctacta aaaaactata ccttaataag agtattgatg gctttttgga aaatttaagt
    16321 aaacaagcgt gtaatattac taatagtaaa gaagctttaa taattataaa tagtcatcat
    16381 aataaggata ctatagttag ttgttataat gttgagcaaa aaaagaaaac aaatttatat
    16441 cctatgattg atatgttttt aaagaaagag tcattagggg gatacctaaa taatttaaaa
    16501 ccatgctcaa aaaagggcat aaatttggaa agttatatat attacaaact tcaggataaa
    16561 aatgagacta taggatgtat agtttgtgca aatagtaaaa actatactag tgatgattta
    16621 aatattctta gtatattgtc caaacaagtt tctgttggga tgcaattata tgaacataat
    16681 gaaaaggaag taaaacacaa agttcttgaa aatgagttga acatattaaa taaacaacaa
    16741 cagcttatta tggataaagg taaaatggat tgtaatgatg agaaagaact ttatttttac
    16801 cataaaccag caagggtagt aggtggagat ttttattatg ctacaaaagt ggatgacgaa
    16861 catatagttt atattgttgc tgatgtaatg ggacatggaa tggtatcaaa ttatgttgtt
    16921 gcaatgataa aaggtgcttt taaagtatta tgcaatcaat acaatacacc aagagaaata
    16981 atgacaaatt taaataggat gttatatgat gaatttgaca agatgggagt atttacaact
    17041 tgtttgatag gtattataga tactaaagaa aatatgatta ctgtgtctaa tgcaggtcac
    17101 tatagtcctg tagttgtaaa gaaagatggc acaatagaaa ataatttaaa ttgtaaaaag
    17161 ggcataccta ttggaataat gaaagatgct acttatgaaa ataatactct ttcaatggaa
    17221 gattatgcaa tggtatgtat gtacactgat ggaattttag agataaaaaa ttcatcaaaa
    17281 gaagagtatg gtataaacag attagaaaac tttctaaaag aaaattttag attaaatcaa
    17341 cagttaatag tagaaaatct aaaattggat ttaaagaatt tctcatcaaa agataattat
    17401 gatgatgata ttttaatagt tatgttaaag gataggtaga ttgattatgg attcaaacga
    17461 taaaaaagga cttaaaagta cagagattat aataataaat ggaagtccaa gaattaataa
    17521 aaattgcagt tttatagcaa ataaagtaaa agctatgcta gaagagtgtg ggttaagttg
    17581 taaaatattt aatatctaca atatggatat tgaatattgc acagcatgtg gattttgtga
    17641 aaaaacaggg tattgcaagt ttaatgatga tatgaagcca ttatataaaa tgtttgatga
    17701 ttcaaaagga actatagtaa taagtcctgt acattttgat tcaatatcag ctaaattaaa
    17761 gactgttgtt gatagaactc aagctatata tgcaagtaaa tatgtattaa ataaaccttc
    17821 aattgataga aataagaaac ggataggaat gtatattgca gtggggggga gtaaatcata
    17881 tgattcacag tttaaaggtg gacagattgt tatggatttt ttctttaaga gtataaatac
    17941 taaactttta cacaatatat atttaaacaa tacagatgat gtatcttata tagataatca
    18001 agaatttaaa gatataatat ataaaaattt aaagatatat attgattcaa tataatttga
    18061 ttttgtaggt aatattatgt ataattgtat tgcaataatt taaataatta aaaggaggga
    18121 atttcaatga aattaccaat agcattatct aataaacatg ttcatttgag tcaagctgat
    18181 atagacgtat tatttggggc gggtcatgag ttaactaaat ttaaaccatt atctcaacca
    18241 gggcaatatg cctgtgaaga aaaagtggat ttagtaggac caaaaggaac tttaaaggga
    18301 gttagagtac taggaccagc tagagctcat actcaagttg aaatatcttt agcagatggt
    18361 ttcccattag gagtaaaagc accaataaaa gaatctggtg atatagctgg aactccaggt
    18421 gttaaattag taggacctgc tggagaagtt gaaatgaaag aaggagttat agttgcttct
    18481 agacatatac atatgagcaa tgaagatgct gctaaatttg gtgtaactga taagcaaata
    18541 gtaaaagtta aaacatctgg accaagagca ttagtatttg aaaatgtatt agtaagagct
    18601 agtgatagct ttaatctaga aatgcatgtt gatatggaag agggaaatgc agcaggcgtt
    18661 aaaaatggag atttagtaga attaatagtt gattaatatt ataaatagac tttatgctag
    18721 tagatatttt atttgctagc atatttttaa atgtaataaa tttctatagg ataaatttaa
    18781 tcgattagat taatttataa aataaagggg tattataaaa aatgtaataa aaacttacaa
    18841 aaa
//
LOCUS       DAMJWO010000081        18722 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.083, whole genome shotgun sequence.
ACCESSION   DAMJWO010000081 DAMJWO010000000
VERSION     DAMJWO010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18722
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.083"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            100..1701
                     /locus_tag="PC366_002957"
     CDS             100..1701
                     /locus_tag="PC366_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HDF2578454.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADRQTYETVILVNTEKSLADGLSASGLSGATKAPILFTQQNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELDSKNIEVKRIGGEDRLKTSYLIAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKSVPFDVKNIQSYCIGSEEIMSNPLVKNTNSVR
                     IEGTDRFETNKNVIDYFFNSADGFYVSDGYQLVDAIAAAPLTKNSPMVLVNDGSDKTV
                     LEGAKNITSVGEINEKVIQQCINASKSNGQPPTITVGSTEIYKGEKFDTGKLNIVAKD
                     NTGKVLPIEVDGFIDTNRVGTYILTLKATDEWGKSTGKRVEIKVLDDKSYDYNSPEFK
                     KMVSTEMYNLINSYRKEKGKEPLVVSSRLEGMANAWSKYMMDKKVFAHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKNVQTTQDAKNLAKAIFEVWKKSPEYNANMLSDEFYSTG
                     FGLYILSDGQVHATQEFLNGNEGSL"
     gene            1920..3509
                     /locus_tag="PC366_002958"
     CDS             1920..3509
                     /locus_tag="PC366_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp12"
                     /protein_id="HDF2578455.1"
                     /translation="MKVNKRVLSIGLTISLIMAGAPNINALSSIEKIQGKDRYETAAK
                     IAQKQTYENVVLVNTDNTLADGLSASGLAGTVKAPILLSQRNSIPSDTEKMLKDVKKV
                     YIIGTEDSIGKSVENELKQKGIEVKRIGGNDRIETSYLIAKEIASIKPIDKVFITNGY
                     TGEADAMSASSVASRDGSPIILTNGKNVPFEKKEGVQCYALGSEEIISNDLVKKTNAV
                     RLAGEDRFETNKKVIKHFYSSAKEFYLSKGYQLVDAVAGSSIAKNAPIVLVDGNSDKS
                     VLRSADKITALGGIDEKTLEQCLSASSLDASAPTITVGNLNIYQGDKFDISKLNIVAK
                     DSNGNDLTPELIGNIDTDKVGKYKVTIKATDIGGKTTSISVEVNVLEYKTNDMNSSEF
                     KRMVSSEMYSLVNSYRKEKGKEPLQVSKNLEGLSNSWSKYMADKGQFSHVINGKKSVE
                     VFTGYGLRSEENIAFVPLVTKSTYTTKDAREVANVIFTVWKKSDKYNENMLNSDFVYT
                     GFGLYILPNGEVYATQEFLNK"
     gene            3735..6011
                     /gene="slpA"
                     /locus_tag="PC366_002959"
     CDS             3735..6011
                     /gene="slpA"
                     /locus_tag="PC366_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HDF2578456.1"
                     /translation="MNKKNIAIAMSGLTVLASAAPVFAAEDMSKVETGDQGYTVVQSK
                     YKKAVEQLQKGLLDGSITEIKIFFEGTLASTIKVGAELSAEDASKLLFTQVDNKLDNL
                     GDGDYVDFLISSPAEGDKVTTSKLVALKNLTGGTSAIKVATSSIIGEVENAGTPGAKN
                     TAPSSAAVMSMSDVFDTAFTDSTETAVKLTIKDAMKTKKFGLVDGTTYSTGLQFADGK
                     TEKIVKLGDSDTINLAKELIITPASANDQAATIEFAKPTTQSGSPVITKLRILNAKEE
                     TIDIDASSSKTAQDLAKKYVFNKTDLNTLYRVLNGDEADTNRLVEEVSGKYQVVLYPE
                     GKRVTTKSAAKASIADENSPVKLTLKSDKKKDLKDYVDDLRTYNNGYSNAIEVAGEDR
                     IETAIALSQKYYNSDDENAIFRDSVDNVVLVGGNAIVDGLVASPLASEKKAPLLLTSK
                     DKLDSSVKAEIKRVMNIKSTTGINTSKKVYLAGGVNSISKEVENELKDMGLKVTRLAG
                     DDRYETSLKIADEVGLDNDKAFVVGGTGLADAMSIAPVASQLRNANGKMDLADGDATP
                     IVVVDGKAKTINDDVKDFLDDSQVDIIGGENSVSKDVENAIDDATGKSPDRYSGDDRQ
                     ATNAKVIKESSYYQDNLNNDKKVVNFFVAKDGSTKEDQLVDALAAAPVAANFGVTLNS
                     DGKPVDKDGKVLTGSDNDKNKLVSPAPIVLATDSLSSDQSVSISKVLDKDNGENLVQV
                     GKGIATSVINKLKDLLSM"
     gene            6247..8592
                     /gene="secA"
                     /locus_tag="PC366_002960"
     CDS             6247..8592
                     /gene="secA"
                     /locus_tag="PC366_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDF2578457.1"
                     /translation="MSVLDAILDKADEQEIKKLNLIVDKIESLEKDMEIKENEQLKEM
                     TNTFRLRLDKGESLDDILPEAFAVVREVSKRVLGMRQYKVQLIGGIVIHQGKIAEMKT
                     GEGKTLVEVAPVYLNALTGKGVHVITVNDYLAERDKELMRPVYEFLGLTVGVILSNQD
                     PSIRKEQYKCDITYGTNSEFGFDYLRDNMVPDLSHKVQRELNFAIVDEIDSILIDEAR
                     TPLIIAGDGDEDLKLYELANNFVKTVKEEDFEMDRKDKTIALTASGISKAESFFGITN
                     LTDIKNIELYHHINQALRGHKLMEKDVDYVISNGEVMIVDEFTGRVMDGRRYTDGLHQ
                     AIEAKEGVEIKNESKTMATVTYQNFFRLYEKLSGMTGTAKTEEGEFESIYKLNVVQIP
                     TNRPVIRADLHDKVFKTEEEKYSAVVEEIIRIHKTRQPILVGTVSVEKSEKLSKMLKK
                     QGIKHQVLNAKQHDKEAEVISKAGKLDAITIATNMAGRGTDISLGAGDKEEEEKVKNL
                     GGLYVIGTERHESRRIDNQLRGRSGRQGDPGTSRFFVSLEDDVIKLYGGKTIEKLMKR
                     TSSKENTAIESKALTRAIERAQKGVEGKNFEIRKNVLKYDDTINEQRKVIYNERNKVL
                     NDEDIKEDIQKMVKDIIQEAGETYLIGRKRDYYGYFKHLYSTFMPADTLLIPGVDKKS
                     VQEIIDSTYEISKRVYDLKKMMIGIDKVAELEKTVLLKVVDQYWIDHIDAMEQLRQYI
                     GLKSYAQKDPFKEYALEGYDMFEALNKNIREATVQYLYKFN"
     gene            9007..10878
                     /locus_tag="PC366_002961"
     CDS             9007..10878
                     /locus_tag="PC366_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp2"
                     /protein_id="HDF2578458.1"
                     /translation="MNKKNLSVIMAAAMISTSVAPVFAAETTQVKKETITKKEATELV
                     SKVRDLMSQKYTGGSQVGQPIYEIKVGETLSKLKIITNIDELEKLVNALGENKELIVT
                     ITDKGHITNSANEVVAEATEKYENSADLSAEANSITEKAKTETNGIYKVADVKASYDS
                     AKDKLVITLRDKTDTVTSKTIEIGIGDEKIDLTANPVDSTGTNLDPSTEGFRVNKIVK
                     LGVAGAKNIDDVQLAEITIKNSDLNTVSPQDLYDGYRLTVKGNMVANGTSKSISDISS
                     KDSETGKYKFTIKYTDASGKAIELTVESTNEKDLKDAKAALEGNSKVKLIAGDDRYAT
                     AVAIAKQTKYTDNIVIVNSNKLVDGLAATPLAQSKKAPILLASDNEIPKVTLDYIKDI
                     IKKSPSAKIYIVGGESAVSNTAKKQLESVTKNVERLAGDDRHMTSVAVAKAMGSFKDA
                     FVVGAKGEADAMSIAAKAAELKAPIIVNGWNDLSADAIKLMDGKEIGIVGGSNNVSSQ
                     IENQLADVDKDRKVQRVEGETRHDTNAKVIETYYGKLDKLYIAKDGYGNNGMLVDALA
                     AGPLAAGKGPILLAKADITDSQRNALSKKLNLGAEVTQIGNGVELTVIQKIAKILGW"
     gene            10985..11692
                     /locus_tag="PC366_002962"
     CDS             10985..11692
                     /locus_tag="PC366_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDF2578459.1"
                     /translation="MVDATLFFTPHQDDETLSMGSAIIEHVEKSDTHVILCTDGSKSI
                     IRKVLDDGGSCSYHIKDVHKYSLSESEFSKDRDEEFKDSCEAMGVKESNIHIEDNRAH
                     DGELSKEKAREIILKYLEEYPDAKVKTVTPFKASGIHEDHRALGEAALELYKEGKIKD
                     LRFYVEPYDYKDFKKVNPNVEVWKVLPSQEEKLLSAMNAYKKWNPESGHYAIGYHSVK
                     SHFDELAINKIQYVHAP"
     gene            11725..13560
                     /locus_tag="PC366_002963"
     CDS             11725..13560
                     /locus_tag="PC366_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF2578460.1"
                     /translation="MKISKKIVSLLTMTFLTVTLYGNTSNASTKDTLTGSGRWETAIK
                     ISQAGWKKSENAVLVNDNSIADALSATPFAKAKDAPILLTQSNKLDSRTKAELKRLGV
                     KNVYLIGGSIALSSEIEKQLNAENISFERISGNSRYDTSLKLAEKLDREKSISKIVVV
                     NGEKGLADAVSVGAIAAQENMPIILSDSENGTEVADNFIDSKDIEKSYVIGGTYSISN
                     SVERSLPNATRIAGSSRSETNAKIIEEFYKDTDIKNIYVTKDGTRSKHDLIDSLAVGV
                     LASKNGSPILLAGNKLDSSQKDVLNTKIIDKVIQIGGLGNENVVEDVIDMQEETKYTV
                     ETIDELNVAIKKSDANDIIRFKPEKDKNITNSFKIETNKAITIEFDGIYKQSITIDMP
                     NGDIKNFGDIDNDLVINNIKNETLVNEGSIQGIDVYDENGCKIENEDSGEIWLITILK
                     NSKDVYILNRGEITKISNNSSSVTIKNSGNINTISGSEEPSISGKKPITNDTDKDEDK
                     KARGLYPKVESCIPALKDYVRITISTKPESSKYKIYYRVVDEKPSAKYVGEKISTKGW
                     SMVTISNQSFIERAKDGSYIEAVEIDTSNNEVSRWGKSSITDDGI"
     gene            complement(13608..14003)
                     /locus_tag="PC366_002964"
     CDS             complement(13608..14003)
                     /locus_tag="PC366_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HDF2578461.1"
                     /translation="MILKKHRETILYLFFGAFTTLVNIVSYLFFTRVILFNFMVANAL
                     AWILAVLFAYVTNKFFVFESKRIEIRFVFKEFLSFVSFRLLSGVVEMLIMYVMIDLLF
                     VNDVIVKIFTNIVVIVLNYLFSKMIIFKK"
     gene            14230..16641
                     /locus_tag="PC366_002965"
     CDS             14230..16641
                     /locus_tag="PC366_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp84"
                     /protein_id="HDF2578462.1"
                     /translation="MRKYKSKKLSKLLALLTVCFLIVSTIPVSAENHKTLDGVETAEY
                     SESYLQYLEDVKNGDTAKYNGVIPFPHEMEGTTLRNKGRSSLPSAYKSSVAYNPMDLG
                     LTTPAKNQGSLNTCWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDM
                     SGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLNK
                     DKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGWDDNYSKD
                     NFASDVKPESNGAWLVKSSWGEFNSMKGFFWISYEDKTLLTDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETD
                     IDGYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKAELQRLGTKKVYLIGGENSLSKNVQTQLSNMGISVERISGSDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISIGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKSQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKNVLKSKKIETPIRVGGNGNESAFNELN
                     TLLGK"
     gene            16938..18515
                     /locus_tag="PC366_002966"
     CDS             16938..18515
                     /locus_tag="PC366_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HDF2578463.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLIGNGRYETAVK
                     ISQKAYSSSSNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRTEKEIKRLGA
                     KDIYLIGGTAVLNKDIENKLKGNGLNVERINGKDRYETSLILANKLKDIKDIKEVAVV
                     NGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVIGGTNSVSR
                     AVEKSLPNAERVSGKDRNETNAKVIEKFYTDTNLSNLYVTKDGSKNENQLIDSLAVGV
                     LAAKNESPVVLVGNKLNTKQRDILSTKKLNTITQVGGNGNEEAFDEIKSLQEKTVFEA
                     KTVEELTDMINIASPNDIINFKPKENTVNEAFRMVTNKPITVNIKGDCSKTLTVDMPN
                     GEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDIDTLMILASA
                     NDTKLINDGYIGKLIDNSSNSDITNNGTIDKKVNQVENLEAKVDSIEKAIDSISQKVN
                     KIQDILDKIGFLKKFLS"
BASE COUNT         7752 a         2073 c         3469 g         5428 t
ORIGIN      
        1 ttcatatcat atatactcta taatatatgg aaaataaaga gaaaataaat agaaaataat
       61 cacaatataa atataaaata taaaaatcat cagggggata tgaaaatgaa caaaaaaata
      121 ttatcattag gtctagcagt atcattaatc ttagtaaact tcaaaagtgt aaatgcatca
      181 tcagtagtag aaaaaatata cggtaaagat agatatgaaa cagcagcaaa gatagctgat
      241 agacagactt atgaaacagt aattttagta aatacagaaa aatcacttgc agatggatta
      301 agtgcaagtg gattatcggg agctacaaaa gctccaatac tatttacaca acaaaataag
      361 ataccagcag acacaaatag atgtctaaaa aatatcaaaa aagcatatat aataggtaca
      421 gaagatacta taagtaaatc agtagaaaaa gaactagatt ctaaaaatat agaagtcaaa
      481 agaattggtg gagaagatag actaaaaaca agctatttaa tagctaaaga aatagcaact
      541 ataaaaaaag tggataaagt actattaact aacgcatata gtggagaagc agacgcaatg
      601 agtgtatcat cagtagctac tagagatgga gctccaatca tacttacaga tggaaagagt
      661 gtgccttttg atgtaaaaaa tattcaatca tattgtatag gttcagagga gataatgagt
      721 aaccctctag ttaaaaatac aaactcagta agaatagaag gaactgaccg atttgaaact
      781 aacaaaaatg taatagacta cttttttaat agtgcagatg gattctatgt atcagatgga
      841 taccaattag tagatgcaat agcagctgca ccacttacta aaaactctcc aatggtacta
      901 gtaaatgatg gaagcgataa aactgtatta gaaggagcta agaatataac ttctgtaggt
      961 gaaataaatg agaaggtaat acaacagtgt ataaatgctt caaagtcaaa tggacaacca
     1021 ccaacaatta cagttggaag tacagagata tataagggtg aaaagtttga cactggcaag
     1081 ttaaacatag tggctaaaga taacactggg aaggtattac caatagaagt tgatgggttt
     1141 atagatacaa atagagtagg tacatacata ttgacattaa aagctacaga cgaatgggga
     1201 aaaagtacag gaaaaagagt agaaataaaa gtgttggatg ataaatccta tgattacaac
     1261 agcccagaat ttaaaaaaat ggtatctact gaaatgtata acttaatcaa ttcctataga
     1321 aaagaaaaag gcaaagagcc tttggtagta tctagtaggc tagaaggtat ggcaaatgca
     1381 tggtctaagt atatgatgga taaaaaagta tttgcacatt atatagatgg aaaaaatgct
     1441 ccacaagtat tttctgagtt tggaatgaga agtgaggaaa atatagcata tatttatata
     1501 gattctaaga acgttcaaac gacacaagat gcaaaaaact tggcaaaggc tatatttgaa
     1561 gtgtggaaga agtctccaga gtacaatgca aacatgctta gtgatgagtt ctatagtact
     1621 ggatttgggc tttatatatt atctgatggt caagtgcatg ctactcagga gtttttaaat
     1681 ggcaatgaag gtagtttgta aaaaattcca taaatcttgt ttttttgtta atttactgat
     1741 attataaaat gaaaatcaca tctaaagtac tttttgtaat ctgttttgtt attgctttac
     1801 aggctatggt attttaggtg ttttttgttt tagtagttta tagattttga gggaatcact
     1861 actgaggatg taatttatga ttagctgaat tatataaaaa aattagtagg aggagttcga
     1921 tgaaggtaaa taagagagta ttatcaatag gattgacaat atcattaata atggcaggag
     1981 caccaaatat caatgcactt tcgagcatag aaaagataca agggaaagat agatatgaga
     2041 cagctgccaa aattgcacag aaacaaacat atgaaaatgt agtattagta aatacagata
     2101 atacactagc tgatggatta agtgcaagtg gattagcagg aacagttaaa gcacctatat
     2161 tattatcaca aagaaacagt ataccatcag acacagaaaa aatgttaaaa gatgtaaaga
     2221 aggtttatat aataggaact gaagattcaa taggaaaatc agttgaaaat gaattaaagc
     2281 aaaaaggaat agaagttaaa agaataggtg gtaatgatag aattgaaaca agttatctta
     2341 tagcaaaaga aatagcttca ataaaaccta tagataaggt ttttataact aatggttata
     2401 caggtgaagc agatgctatg agtgcgtcat cagtagcatc aagagatgga tcacctataa
     2461 ttttaactaa tggtaaaaat gttccatttg agaaaaaaga aggtgtgcaa tgttatgctc
     2521 ttggttcaga ggagataata agtaatgatt tagttaaaaa aactaatgca gttagattag
     2581 ctggagaaga tagatttgag actaataaaa aagttataaa acatttttat agttcggcaa
     2641 aagaatttta tctttctaaa ggttatcaat tagtagatgc agttgctggt tcttctatag
     2701 caaaaaatgc acctattgta ttagttgacg gaaatagtga taagtctgta cttagaagtg
     2761 ctgataagat tacagcacta ggaggaatag atgaaaagac actagaacaa tgtttaagtg
     2821 catcatcact ggatgcaagt gcaccaacaa taactgttgg aaatttaaat atttatcaag
     2881 gtgataagtt tgatataagt aaactgaata tcgtagcaaa ggatagcaat ggtaacgatt
     2941 tgacaccaga gcttatagga aatattgata ctgataaggt gggtaaatac aaagttacta
     3001 taaaagctac tgatattggt ggaaagacta catcaataag tgtagaagta aatgtacttg
     3061 aatataagac taatgatatg aatagtagtg agtttaaaag aatggtttct agtgaaatgt
     3121 atagtttggt aaattcatat agaaaagaaa aaggtaaaga gccattacaa gtttctaaaa
     3181 acttagaagg actttctaat tcctggtcta agtacatggc agataaaggt cagttttcac
     3241 atgtaataaa tggtaagaaa tctgttgaag tatttactgg atatggcttg agaagtgaag
     3301 aaaatatagc ttttgtacca cttgttacaa aaagtactta tacaacaaag gatgctagag
     3361 aagtagcaaa tgtaatattt acagtttgga aaaagtcaga taaatataat gaaaatatgt
     3421 taaatagtga ttttgtatat actgggtttg gattatatat attgcctaat ggagaagtgt
     3481 atgctacaca agaattttta aataagtaat ttaaataagt aaaatcaaat tttttaagtt
     3541 attaaatatt ggagtttaag ggtataaaaa ctcatatgct tgggaaaaat aataatttca
     3601 aaaaaatgac ttgcaaaaag aataaaaatg gattattata gagatgtgag aaatattagg
     3661 aatatatgga tgattattct atgtacataa tgaagagatg taattttaat ataatgttgg
     3721 gaggaattta agaaatgaat aagaagaata tagcaatagc tatgtcagga ttaacagtat
     3781 tagcttctgc agcacctgtg tttgcagcag aagatatgtc gaaagttgag actggtgatc
     3841 aaggatatac agtagtacag agcaagtata agaaagcagt tgaacaatta caaaaagggt
     3901 tattagatgg aagtataaca gagattaaaa ttttctttga gggaacttta gcatctacta
     3961 taaaagtagg agctgagctt agtgcagaag atgcaagtaa attattgttt acacaagtag
     4021 ataataaatt agacaattta ggtgatgggg attatgtaga tttcttaata agctctccag
     4081 cagagggaga taaagtaact acaagtaaac ttgttgcatt aaaaaattta acaggtggaa
     4141 ctagtgcaat aaaagtagct acaagtagta ttattggtga agtcgaaaat gctggtactc
     4201 cgggagcaaa aaatacagct ccaagtagtg ctgcagttat gtctatgtca gatgtatttg
     4261 atacagcttt tacagattca actgaaactg ctgtgaaact tactataaaa gatgctatga
     4321 aaactaaaaa gtttggttta gttgatggaa ctacttattc aacaggtctt caatttgcag
     4381 atggaaaaac agaaaaaatt gttaaattag gagatagtga tactataaat ttagccaaag
     4441 aattaataat aacacctgca agtgcaaatg atcaagctgc gactattgag tttgctaaac
     4501 caacaacaca atctggaagc ccagtaataa ctaaacttag aatattgaat gcaaaagaag
     4561 agacaataga tattgatgct agttctagta aaacagcaca agatttagct aaaaaatatg
     4621 tatttaataa aacagattta aatactcttt acagagtatt aaatggggat gaagcagata
     4681 ctaatagatt agtagaagaa gttagtggaa aatatcaagt ggttctttat ccagaaggaa
     4741 aaagagttac aactaagagt gctgcaaagg cttcaattgc tgatgaaaat tcaccagtta
     4801 aattaactct taagtcagat aagaagaaag acttaaaaga ttatgtggat gatttaagaa
     4861 catataataa tggatattca aatgctatag aagtagcagg agaagataga atagaaactg
     4921 caatagcatt aagtcaaaaa tattataact ctgatgatga aaatgctata tttagagatt
     4981 cagttgataa tgtagtattg gttggaggaa atgcaatagt tgatggactt gtagcttctc
     5041 ctttagcttc tgaaaagaaa gctcctttat tattaacttc aaaagataaa ttagattcaa
     5101 gcgtaaaagc tgaaataaag agagttatga atataaagag tacaacaggt ataaatactt
     5161 caaagaaagt ttatttagct ggtggagtta attctatatc taaagaagta gaaaatgaat
     5221 taaaagatat gggacttaaa gttacaagat tagcaggaga tgatagatat gaaacttctc
     5281 taaaaatagc tgatgaagta ggtcttgata atgataaagc atttgtagtt ggaggaacag
     5341 gattagcaga tgccatgagt atagctccag ttgcatctca attaagaaat gctaatggta
     5401 aaatggattt agctgatggt gatgctacac caatagtagt tgtagatgga aaagctaaaa
     5461 ctataaatga tgatgtaaaa gatttcttag atgattcaca agttgatata ataggtggag
     5521 aaaacagtgt atctaaagat gttgaaaatg caatagatga tgctacaggt aaatctccag
     5581 atagatatag tggagatgat agacaagcaa ctaatgcaaa agttataaaa gaatcttctt
     5641 attatcaaga taacttaaat aatgataaaa aagtagttaa tttctttgta gctaaagatg
     5701 gttctactaa agaagatcaa ttagttgatg ctttagcagc agctccagtt gcagcaaact
     5761 ttggtgtaac tcttaattct gatggtaagc cagtagataa agatggtaaa gtattaactg
     5821 gttctgataa tgataaaaat aaattagtat ctccagcacc tatagtatta gctactgatt
     5881 ctttatcttc agatcaaagt gtatctataa gtaaagttct tgataaagat aatggagaaa
     5941 acttagttca agttggtaaa ggtatagcta cttcagttat aaataaatta aaagatttat
     6001 taagtatgta atataaatat aataatataa aaaggcttct tatatgagaa gtctttttat
     6061 attatgtttt cgaatacaaa aaaagagact aaatttagtc tcttttttat gtgagaaata
     6121 cttaaatata taaagatgta atttatttaa gtatgattat tatactatac aataaaataa
     6181 ttgtctacta ttctataatt ttaaggtata ataataattg tatgataaaa gaggaggtca
     6241 aaaaatatgt cagttttaga tgcaatctta gataaagcgg atgaacaaga aattaaaaaa
     6301 ttaaatttaa tagtagataa aatagaatct ttagaaaaag atatggaaat caaagagaat
     6361 gaacaattaa aagaaatgac aaatactttt agacttagat tagacaaagg tgaaagtttg
     6421 gatgatatac ttccagaagc atttgctgtt gttagagagg tctcaaaaag agttttagga
     6481 atgcgtcaat ataaagttca gttaattgga ggtatagtaa ttcatcaagg aaagatagct
     6541 gagatgaaga ctggtgaggg gaaaacttta gttgaggtag ctccagtata tctaaatgct
     6601 ttaacaggaa aaggtgtaca tgtaattaca gtaaatgatt atttggcaga acgtgataaa
     6661 gaacttatgc gtccagtata tgaattttta ggattgactg taggtgtaat tttatctaac
     6721 caagacccaa gtataagaaa agaacaatat aaatgtgata taacttatgg aacaaatagt
     6781 gaatttggat ttgactattt aagagataat atggtgccag atttgtctca taaagtacaa
     6841 agggaactaa actttgccat agtagatgag atagactcaa tattaataga tgaagctaga
     6901 actccactta ttattgcagg agatggtgat gaagatttaa aactttatga gttagcaaat
     6961 aactttgtaa aaactgttaa agaagaagac tttgagatgg atagaaaaga taaaactata
     7021 gcattaacag caagtggtat aagcaaagct gagtcatttt ttggtataac aaaccttact
     7081 gatataaaga atatagaatt atatcatcat ataaatcaag ctttaagagg tcataagctt
     7141 atggaaaaag atgttgacta tgttatctca aatggagaag taatgatagt tgacgaattt
     7201 acaggaagag taatggatgg tagaagatat acagatggac ttcaccaagc tatagaagcc
     7261 aaagaaggtg ttgagataaa gaatgaatct aaaactatgg ctactgtgac ttatcaaaat
     7321 ttcttcagac tatatgaaaa actttctggt atgactggta ctgcaaagac agaagaaggg
     7381 gaatttgagt caatctataa attaaatgtt gtccaaatac caactaatag accagttatt
     7441 agagctgatt tgcatgataa ggtatttaaa acagaagaag aaaagtatag tgctgttgta
     7501 gaagaaataa taaggataca taagactaga cagccaatac tcgtgggaac agtttctgtt
     7561 gaaaaatctg agaagttatc taaaatgctt aagaagcaag gtattaagca tcaagtctta
     7621 aatgctaaac aacatgataa agaggcagag gtaatttcta aagctggtaa attagatgct
     7681 ataacgattg ctacaaatat ggcaggtaga ggtacggata tttctctagg tgcaggagat
     7741 aaagaagaag aagaaaaagt taaaaattta ggtggtcttt atgttatagg aacagaaaga
     7801 cacgaatcaa gaagaattga caatcagctt agagggcgtt ctggtcgtca aggagaccca
     7861 ggtacatcaa gattttttgt aagtcttgaa gatgatgtaa taaagcttta tggtggaaaa
     7921 actatagaga aacttatgaa gagaacaagt tcaaaggaaa atacggctat tgaaagtaaa
     7981 gcacttacaa gggctataga aagagcacaa aaaggtgtag aaggtaagaa ttttgaaata
     8041 agaaaaaatg ttcttaaata tgatgatact attaatgagc aaagaaaggt tatatataat
     8101 gaaagaaata aagtgttaaa tgatgaagat ataaaagaag atattcaaaa aatggttaaa
     8161 gacatcatac aagaagcagg agaaacttat ttaattggaa gaaaaagaga ttattatgga
     8221 tattttaaac atttatatag tacatttatg cctgcagata cattactaat acccggtgta
     8281 gataaaaaaa gtgtccaaga gataattgat agcacatatg aaatttcaaa aagggtttat
     8341 gacttgaaaa agatgatgat tggtattgat aaagttgcgg agttagaaaa aacagtactt
     8401 ttaaaagtgg ttgatcaata ctggatagat catatagatg ctatggaaca gttaagacag
     8461 tatataggtc ttaaatctta tgctcaaaaa gatccgttta aagaatatgc tttagaagga
     8521 tatgatatgt ttgaagcttt aaataaaaat ataagggaag caacagtaca atacttatat
     8581 aaatttaact aaaaaagttc atgtaatttt tattaaatga aaaataaaat attttgattc
     8641 tttatattgt aattacaatt aaataattaa ggaatacaaa tgaaaaagaa gctgaaaatc
     8701 agcttctttt tctgtgtgag aaatacggaa aaaagagatg cttgaaattt ctttcttcca
     8761 tttaatatta tactataaag aagatgaaaa gtctattagt tataaactgg attattaaaa
     8821 aaaattacaa ttttgttact tttttgtata cataaatatt aaaaaaataa aatataagaa
     8881 aaagtttata tcttttggtt aattattaca ataagtctca tttattgaaa taatatcaaa
     8941 tatatattat aattggtaaa taaggaaaaa ataataaaaa tttgaatttt ttagggggaa
     9001 aataccatga ataaaaaaaa tctttctgta attatggctg ctgcaatgat aagtacatca
     9061 gtagctccag tttttgctgc agaaactaca caggtaaaaa aagaaacaat aactaagaaa
     9121 gaagctacag aactagtttc gaaagttaga gatttaatgt ctcaaaagta tactggtggt
     9181 tctcaagttg gacaaccaat atatgaaata aaagttggcg agactttatc aaaattaaaa
     9241 ataataacta atatagatga attagagaaa ttagtaaatg ctttgggaga aaataaagaa
     9301 cttattgtaa ctataacaga taaagggcat ataacaaata gtgcaaatga agtagttgca
     9361 gaagcaactg aaaaatatga aaattcagca gacctttccg ctgaggctaa ttctataaca
     9421 gaaaaagcta aaactgaaac taatggaatt tataaagttg cagatgtaaa agcttcatat
     9481 gatagtgcta aagataagtt agttataact ttaagagata aaacagacac agtaacttct
     9541 aaaactatag agataggtat tggtgatgaa aaaattgatt taacagcaaa tccagttgat
     9601 tcaacgggaa caaacttaga cccttctaca gaaggattta gagtaaataa aatcgttaaa
     9661 ctaggtgtag caggagctaa aaatattgat gatgtccaat tagctgaaat aactataaaa
     9721 aatagtgacc taaatacagt ttcaccacaa gatttatatg atggatatag attaactgtt
     9781 aaaggtaata tggtagcaaa tggaacatca aagtcaatta gtgatatttc atcaaaagat
     9841 tcagaaacag gaaagtataa atttactatt aagtatactg atgcatctgg aaaagcaata
     9901 gagcttactg tagaaagtac taatgaaaaa gatttaaaag atgccaaagc tgcattagaa
     9961 ggtaattcaa aggttaaatt gatagctgga gatgatagat atgcaactgc agtggctata
    10021 gcaaaacaaa caaaatatac tgacaatata gttatagtta attcaaataa actagttgat
    10081 ggattagcag ctacaccact tgctcaatct aaaaaagcac ctatattatt agcatccgat
    10141 aatgaaatac caaaagtaac tttagattat ataaaagata taattaagaa aagcccatca
    10201 gctaaaatat atatagtagg tggagaatca gcagtatcaa atacagctaa aaagcaatta
    10261 gaatcagtaa ctaagaatgt tgaaagacta gctggagatg atagacatat gacttctgta
    10321 gcagtagcaa aagctatggg gtcttttaaa gatgcatttg tagtaggtgc gaaaggggag
    10381 gctgatgcta tgagtatagc tgccaaagct gctgaactta aggctcctat aatagtaaat
    10441 ggctggaatg atctttcagc agacgctatc aaattgatgg atggaaaaga gattggtata
    10501 gttggtggtt ctaacaatgt atctagtcaa attgaaaatc aacttgctga tgttgataaa
    10561 gatagaaaag ttcaaagagt tgaaggagaa acaagacacg atactaatgc taaggttata
    10621 gaaacatatt atggaaaatt agataaacta tatatagcaa aagatggata tggaaataat
    10681 ggtatgctag tagatgcatt ggcagcagga cctctagcag caggtaaagg tccaatactt
    10741 ctagctaaag ctgatataac agactcacaa aggaatgcac ttagtaaaaa attaaatctt
    10801 ggtgcagaag taactcaaat aggtaatgga gttgaattga cagtaataca aaagatagct
    10861 aaaatactag gttggtaata acttatactg tggagaagat tccttaatta atacaggaat
    10921 ctttttctat aattatgcta tttattgtaa attataacat tttataaagt aggaggatgt
    10981 agtagtggta gatgcaactt tattttttac accacatcaa gatgatgaaa ccttaagtat
    11041 gggaagtgct ataattgaac atgttgaaaa aagtgataca catgtcatat tatgcacaga
    11101 tggtagtaaa tctataataa gaaaagtttt ggatgatgga gggtcatgtt cttatcatat
    11161 taaagatgtt cataaatact ctttatcaga aagtgaattt tcaaaagata gagatgaaga
    11221 atttaaggat agctgtgaag caatgggtgt aaaagaaagt aatatacata tagaagataa
    11281 tagagcacat gatggtgagt taagtaaaga aaaggcaagg gaaataatac ttaagtactt
    11341 agaagaatat ccagatgcaa aagtaaaaac tgttactccg tttaaagcta gtggaataca
    11401 tgaagaccat agggcattag gagaagctgc actagagtta tataaagaag gcaaaataaa
    11461 agatttaaga ttttatgtag aaccatacga ctataaggat tttaaaaaag ttaatccaaa
    11521 tgtagaggta tggaaggtat tacctagtca agaggagaag ttattaagtg caatgaatgc
    11581 atataaaaaa tggaatcctg aaagtggaca ttatgctata ggatatcatt cagtaaaatc
    11641 tcattttgat gagctagcta taaataaaat acagtatgta catgctccat aaaatattat
    11701 gaaagaatta ggaggtaaga attaatgaaa atatcaaaaa agatagtgtc tttgttaact
    11761 atgacatttt taactgttac attatatgga aatacatcta atgcatctac aaaagataca
    11821 ttaacaggtt ctggaagatg ggaaacagca ataaaaataa gtcaagcagg atggaaaaag
    11881 tctgaaaacg ctgtgctagt aaatgataat tcaatagcag atgctttatc agctactcca
    11941 tttgctaaag caaaagatgc accaatatta ttaactcaaa gtaataaatt ggatagtaga
    12001 acaaaagcag aattaaaaag acttggtgtg aaaaatgtat atttaatagg tggttcaatt
    12061 gcattaagtt cagagattga aaagcagtta aatgcagaaa atataagttt tgaaagaata
    12121 tctggaaata gtagatatga tacttcttta aaattagctg aaaagctaga tagggaaaaa
    12181 tctatatcta aaatagtagt agtaaatgga gaaaagggtc ttgctgatgc agtgagtgtt
    12241 ggagctatag ctgctcaaga aaacatgcca ataatacttt ctgattcaga gaatggaact
    12301 gaagtagctg ataattttat agatagtaaa gatatagaaa aatcgtatgt aataggtggt
    12361 acatattcta tttctaattc tgtagaaaga agtttaccaa atgcaacaag aatagcaggt
    12421 agtagtagaa gtgagacaaa tgcaaaaatt atagaagaat tttacaaaga tactgatata
    12481 aaaaatattt atgtaacaaa ggatggtaca aggagtaagc atgatttaat agattcttta
    12541 gctgtgggtg tattagcttc taaaaatggt tctccaatac ttttagcagg aaataagcta
    12601 gatagttctc aaaaagatgt gttaaacact aaaattatag ataaagttat tcaaattggc
    12661 ggattgggta atgaaaatgt tgtagaagat gtaatagata tgcaagaaga aactaagtat
    12721 actgttgaaa ctattgatga acttaatgtt gctataaaaa aatcagatgc aaatgacatc
    12781 ataagattta agccagaaaa agataaaaat ataactaatt cttttaaaat agaaacaaat
    12841 aaagctataa ctattgaatt tgatggtata tataaacaat caataactat agatatgcca
    12901 aatggagata taaaaaactt tggggacata gataatgatc tagtaataaa taatataaaa
    12961 aatgagactt tagttaacga aggaagtata caagggatag atgtttatga tgagaatgga
    13021 tgtaaaatag agaatgagga ttctggagaa atatggctta taacgatact taaaaattca
    13081 aaagatgtat atattttgaa tcgtggagaa ataactaaaa tatctaataa ttcttctagt
    13141 gtaacaataa aaaattcagg taatattaat actataagtg gaagtgaaga accatcaata
    13201 agtggtaaaa aacctataac taatgataca gataaagatg aagataaaaa ggcacgtggt
    13261 ttatatccta aagtagaatc ttgtatacct gctttaaaag attatgtaag aataactata
    13321 tcaacaaaac cagagagttc aaagtataaa atttattata gagtagttga tgaaaaacca
    13381 tctgcgaaat atgttggaga aaaaattagt actaaaggtt ggagtatggt tacaatatca
    13441 aatcaatctt ttattgaaag agccaaagat ggatcatata tagaagcagt agaaatagat
    13501 acctcaaata atgaagtttc acgatgggga aaatctagca ttacagatga tggaatttag
    13561 acattaaact tattcatttt gcagattact atttagtaat ctgctattta ttttttaaaa
    13621 attatcatct tgctaaacaa gtaatttaaa actataacaa ctatattagt aaatattttt
    13681 acaataacat catttacaaa aagcaaatca atcattacat acataattaa catttcaacg
    13741 acaccagaaa gtagcctaaa actaacaaaa gacaaaaatt ctttaaatac gaaccttatt
    13801 tcaattcttt tactttcaaa tacaaaaaac ttattagtaa cataagcaaa taaaacagca
    13861 agtatccatg ccaaagcatt tgcaaccata aaattaaata aaataactct agtaaaaaat
    13921 aaatacgaaa ctatatttac aagagtagta aatgctccaa aaaataaata taatattgtc
    13981 tctctatgct tttttaaaat caaatataat cctcctaatc taatttaata taaatatact
    14041 taaagatact aacaaacatt agtatagcac atctattaat aaatcaatat atcttaaaat
    14101 attataaaaa taaaactata atattctata attaatatgt actcataatc catattttat
    14161 caaaataaaa tatgacctta atttagaaat ctgatataat aaaaattaaa tacatataag
    14221 ggggtaaaca tgagaaagta caaatcaaaa aaattgtcaa agctactggc attgttgaca
    14281 gtttgctttt taatagtgtc aacaatacct gtctcagcag aaaaccataa aactctagat
    14341 ggagtagaaa ctgcagagta ttctgaaagt tatcttcaat acctagaaga tgtcaaaaat
    14401 ggagacacag caaaatataa tggagtaata ccttttccac atgaaatgga aggtacaaca
    14461 cttcgaaata agggcagaag tagtcttcca tcagcatata aatcaagtgt agcatacaac
    14521 ccaatggatc ttggtcttac tacaccagca aaaaatcaag gaagtcttaa tacatgctgg
    14581 tctttttcag gtatgtcaac tttagaagca tatcttaaat taaagggata tggaacgtat
    14641 gacttatcag aagaacattt aagatggtgg gcaactggtg gaaaatatgg atggaactta
    14701 gatgatatgt caggtagttc aaatgtaaca gccataggat atctgacagc atgggcaggt
    14761 cctaagttag aaaaagatat accatataat cttaaatctg aggcacaagg tgcaactaaa
    14821 ccttcaaata tggatactgc acctactcaa tttaatgtaa cagatgttgt tcgtcttaat
    14881 aaagataagg aaactgtaaa aaatgctata atgcaatatg gttcagtgac atcaggttat
    14941 gcacattatt cgacatattt taataaagat gaaacagcat ataactgtac aaataagagg
    15001 gctccattaa atcacgctgt agcgatagta ggatgggatg ataattattc aaaagataac
    15061 tttgcatctg atgtaaaacc agaatcaaat ggagcatggt tagtaaaaag cagttgggga
    15121 gaatttaatt ctatgaaagg attcttctgg atttcttatg aagataaaac tctactaaca
    15181 gatacagata actatgcaat gaaatcagta tcgaaaccag atagtgataa aaaaatgtac
    15241 caacttgaat atgctggtct tagtaagata atgtcaaata aagtaacagc agcaaatgta
    15301 tttgatttta gcagagattc tgaaaaactt gactctgtta tgtttgaaac agactctgta
    15361 ggagcaaaat atgaagtata ttatgcacca gtagtaaatg gagttcctca aaacaactca
    15421 atgacaaaac ttgcaagtgg aacagtatca tattctggat acataaatgt acctactaat
    15481 tcttacagct taccaaaagg taaaggagca atagtagtag ttatagacaa cacagcaaat
    15541 cctaatagag aaaaatcaac tttagcatat gaaactgata tagatggata ctatctatat
    15601 gaggctaaag caaacttagg tgaaagctac atacttcaaa acaataagtt tgaagatata
    15661 aatacatata gtgaattttc tccttgtaac tttgttataa aagctataac aaaaacatct
    15721 tctggacaag ctacttcagg agaatcttta actggagcag atagatatga aacggcagtt
    15781 aaagttagtc aaaaaggatg gacttcttca caaaatgcag tattagtaaa tggagacgca
    15841 atagtggatg ctttaacagc tacaccattt acagcagcaa tcgactctcc aattctttta
    15901 acaggaaaag ataacttaga ttcaaaaact aaggcagagt tacaaagatt aggaactaaa
    15961 aaagtttatc taataggtgg agaaaattct ttaagcaaga atgtacaaac tcaacttagt
    16021 aatatgggta tatcagtaga aagaatttca ggtagtgata gatacaagac tagtatatct
    16081 ctagctcaaa agttaaatag tataaaatct gtttcacaag ttgcagtggc aaatggtgta
    16141 aatggacttg cagatgcaat aagtattggt gcagcagctg ctgataacaa tatgccaata
    16201 atacttacta atgaaaagag tgagttgcaa ggtgctgatg agtttttaaa ttcatcaaaa
    16261 ataactaagt cttatataat tggtggtaca gctactttat catcaaattt agaaagtaag
    16321 ctttcaaatc caacaagact tgcaggaagt aatagaaatg aaactaatgc taagataata
    16381 gataaattct accctagctc agatttgaaa tatgcttttg ttgttaaaga tggttcaaag
    16441 agtcaaggag acttgataga tggactagca gtaggagcat taggtgctaa aactgattca
    16501 ccagtagttc tagttggaaa taagttagat gaaagtcaaa aaaatgtact taagtctaag
    16561 aaaatagaaa ctcctattag agttggtgga aatggaaatg aaagtgcttt taatgaacta
    16621 aatactcttt taggaaaata gtgaatggaa agatagtaag gatatacatt ttattattaa
    16681 aaaatattca atagaagttt ataaatataa aataacaaaa aggggtgtct caaaatgaac
    16741 tttttagttc atgaggcact cttttttgtt gttttatatt tttatcattt aaataatgaa
    16801 aaataggctt gtctatattt ttagatagtt ttcttattat tgatgaaaaa tgtaataatt
    16861 ttaaactgta aaatagtgta aagttatttt ataatataaa tatagtaaga ttttaaacaa
    16921 aataaggggg aataataatg aaagcaccaa aaactatttt aacaatactg acaatagcgc
    16981 ttactttaag tagcatttct ataataccat catatgcact tacagaggaa aaattaatag
    17041 gtaatggtag atatgaaact gctgtaaaga taagtcaaaa ggcatacagt tctagttcta
    17101 atgtagtgtt agttaatgac aattcattag ctgatgcact ttcagctaca ccatttgcaa
    17161 aggctaaagg agcaccaata cttttgacag aaagtgataa gctagatgat aggactgaaa
    17221 aagagataaa acgtctagga gctaaagata tttatttgat aggaggtact gctgtactta
    17281 ataaagatat agagaacaag ttaaaaggta atggacttaa tgtagaaaga attaatggta
    17341 aggatagata tgaaacttca ctgattttgg ctaataagct taaggatata aaagatatta
    17401 aggaagttgc tgtagtaaat ggtgaaaaag gattaagtga tgctgttagt gttggagcac
    17461 cagcagctca aaataagatg cctataattt tgtctagtcc taaggacgga gtagaagcat
    17521 ttgataaatt tataagagat gagaaagtta taaaagcata cgtaattgga ggaacaaatt
    17581 ctgtttcaag agctgtagaa aagagccttc ctaatgcaga aagagtgagt ggaaaagata
    17641 gaaatgagac taatgccaaa gttatagaaa agttttatac tgatacaaat ttaagtaatt
    17701 tatatgtaac taaggatggt agtaaaaatg agaatcaact aatagactcg ttagctgttg
    17761 gagtattggc tgcaaaaaat gagtctcctg ttgttttggt tggtaataaa ttaaacacga
    17821 aacaaaggga tatacttagt actaaaaaat taaatactat aacacaggta ggtggaaatg
    17881 gaaatgaaga agcttttgat gaaattaaga gtttacaaga aaaaactgtg tttgaagcaa
    17941 aaactgttga ggaattaact gatatgataa atatagcaag tcctaatgat attataaact
    18001 ttaaaccaaa agagaatact gtaaatgaag cttttagaat ggtaacaaat aaaccaataa
    18061 ctgtgaatat aaagggtgat tgttcaaaga ctcttacagt agatatgcct aatggtgaag
    18121 tgaataacta tgctactttg gtaaatgtta tagttagaaa tattggagaa ggtggattta
    18181 ataaccatga tacaatcact atattgtcag ttcgtgacaa aaatggtaga gttatagaaa
    18241 atactagaaa ttcagatata gatacgttga tgatattagc ttctgctaat gatacaaaat
    18301 tgattaatga tggatatata ggaaagctta tagataattc atctaatagt gatataacta
    18361 ataatggtac tatagataaa aaagttaatc aagttgagaa tttagaggct aaagtagatt
    18421 caattgaaaa agctatagat tctataagtc aaaaagtcaa taaaatacaa gatatactag
    18481 ataagattgg atttctaaag aaatttctta gttaagaata tgtatattta agtgaagtgt
    18541 gtgttgtaat tgttctaaag ttatatagtt aaacaggttt atatacaaac agacttatag
    18601 ataaatatgt agtttagtat atatttgaat aagctttggg gaggtaacat ggggattgga
    18661 attgaatgta acaaaaaaat aaataaaagt attgacaaaa ctagaataaa gaaaaataat
    18721 ct
//
LOCUS       DAMJWO010000082        18634 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.084, whole genome shotgun sequence.
ACCESSION   DAMJWO010000082 DAMJWO010000000
VERSION     DAMJWO010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18634
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.084"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..962
                     /locus_tag="PC366_002967"
     CDS             <1..962
                     /locus_tag="PC366_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sensor domain-containing diguanylate cyclase"
                     /protein_id="HDF2578464.1"
                     /translation="KLSMKYEILEKEIIHKEELRLSNECYKIIVEQTDSVVFEWNIKE
                     NKSFVSQAWTEKFGYNNACKNIFKEIKDKDLVHSEDKAIFEGFLESIKKKNIHSQAVY
                     RLKKSNGEYIWCRTSITSIYNDENELLRVVGVIVDVDSDIKKYEELRTRAESDSLTNI
                     YNKGTFEKLVEETIVMNTGDKKDALFIIDLDDFKEINDNFGHPFGDFVLKTFADKIQA
                     SFGNKDLVGRIGGDEFVVYMQDYVTEVNLHKKAKELNRVLSDNYTDLSFSFDSSVSIG
                     IARYPQDGTSFFELFKNADRALYSIKASGKNSYCLFEEELYVQ"
     gene            complement(1652..2482)
                     /locus_tag="PC366_002968"
     CDS             complement(1652..2482)
                     /locus_tag="PC366_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2578465.1"
                     /translation="MSQVSKNYFTTGEFAKICGINKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLREVKMPLKEIKAYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKNACNIDANTITLKEHEEEYLVKTPITYKEQFLGDEEENFLYECI
                     NFMDNYELSDYGTIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKPKGLYVTA
                     YHKGSYETIYKAYEKLLNFFNQNNLRIGDFVYEEYLLYDISVRDSNEYLTQISAEVKI
                     "
     gene            2555..4282
                     /locus_tag="PC366_002969"
     CDS             2555..4282
                     /locus_tag="PC366_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578466.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGV
                     VKGDIDYIVKTGLIMMIVAGITALSAVLVCKVSANLSSGFCRDIREAVFVKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKAMTIIIV
                     VVMFLFMLSAFLVGKKLIKLFKMMQIKMDNMNRVLREVVTGVRVIRAFNREHFEKKRF
                     DRTAIDYSETAISINKVFAVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALI
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNGRKDTVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISI
                     NGQDVKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEIKHAASIAQADE
                     FISDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            4319..6181
                     /locus_tag="PC366_002970"
     CDS             4319..6181
                     /locus_tag="PC366_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578467.1"
                     /translation="MSEKRIDEQDIEVLSFEDGMSAEKVKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLISAVFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRRAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPKGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHKELIEKKGFYEELYNSQFSSEYDEEVV"
     gene            6514..7203
                     /locus_tag="PC366_002971"
     CDS             6514..7203
                     /locus_tag="PC366_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HDF2578468.1"
                     /translation="MNKKLNYRFEMKHKITEADVLALKSRLYPIMKKDENASKDGKYL
                     IRSLYFDTPEDKALLDKLNGVAIREKFRIRFYNNNCSYIRLEKKIKHYNMTSKLSTNL
                     TKKEVINILNNDIEFLKESTNCLLREFYLKLKCERLEAKSIVDYNREAFIYPVGNVRV
                     TIDSDIKTSVNSIDLFNKDLPTVSVIDENMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            7308..7994
                     /locus_tag="PC366_002972"
     CDS             7308..7994
                     /locus_tag="PC366_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HDF2578469.1"
                     /translation="MILIMTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMV
                     YKKTYMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDP
                     MDLVFLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNED
                     SEDIATDKIKKVFTKYQIKSKSVTPEKGIELVFEVRMKYGETSLINDLSQVDGVTNAV
                     LVSYNGDYVA"
     gene            8011..9918
                     /locus_tag="PC366_002973"
     CDS             8011..9918
                     /locus_tag="PC366_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HDF2578470.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGVYSTSSNKSVDLYSDVYIEKYF
                     NRDKVMEVNIEIDESDLKDMNENAIKEEFKVAKVTVDGDTYGNVGIRTKGNSSLTSVA
                     NSDSDRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLATPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGNVTGDLYKSDEGSSLQYKGDDPESYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETHKTKYHKYLEEIVTKYLDSDYLENMTTKLHDMIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDNNNSNNSDSNNNSNSENKRSGNQSDKKEVNAELTSSVVKT
                     NTDNETENKTTNDSESKNNTDKDKSGNDNNQKLEGPRGKGGKSIPGVLEVAEDMSKTI
                     KSQLSGETSSTKQNSGDESSSGIKGSEKFDEDMSGMPEPPEGMDGKMPPGMGNMDKGD
                     MNGKNGNMNMDRNQDNPREAGGFGNRGGGSVSKTTTYFKLILGGASMIIMSIMLVGVS
                     RVKRRRFIKSK"
     gene            10371..11060
                     /locus_tag="PC366_002974"
     CDS             10371..11060
                     /locus_tag="PC366_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578471.1"
                     /translation="MLQKVLWKFLKLVVGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADS
                     LFVGIIMLILGLVLLSVGMVFYMGSGLGSGPRDGLMVAIQKKTGKSLKLIRGTIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAAVQNIVK"
     gene            11496..12035
                     /locus_tag="PC366_002975"
     CDS             11496..12035
                     /locus_tag="PC366_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2578472.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            12054..13097
                     /locus_tag="PC366_002976"
     CDS             12054..13097
                     /locus_tag="PC366_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578473.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKENN"
     gene            13099..13935
                     /locus_tag="PC366_002977"
     CDS             13099..13935
                     /locus_tag="PC366_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2578474.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYMKVFGRSILLAGGATLICLIVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            14040..14714
                     /locus_tag="PC366_002978"
     CDS             14040..14714
                     /locus_tag="PC366_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2578475.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGIK"
     gene            14714..15766
                     /locus_tag="PC366_002979"
     CDS             14714..15766
                     /locus_tag="PC366_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2578476.1"
                     /translation="MIKFKKTISLIAVGMMTVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPMDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITQNPVAYPSKEVLDKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            16210..17058
                     /locus_tag="PC366_002980"
     CDS             16210..17058
                     /locus_tag="PC366_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDF2578477.1"
                     /translation="MNRINKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSVVGLITSSIIIFMYTSYILYNNITHNMDVEFISYMWIIATPVSSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGENKTNKIVKYIGSNIIECTRNEDIIYSLQKDMIGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYKSSFGDSINFKNIVEE
                     ELQYDV"
     gene            17048..>18634
                     /locus_tag="PC366_002981"
     CDS             17048..>18634
                     /locus_tag="PC366_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2578478.1"
                     /translation="MMFKIFNKSLLKLVIVLSIVLTISNFSLFSYASEITSSTDKVLI
                     IYDSKKETAYNRDILNIMRTLLGRFSSDIELLKLSNYDGEINENYYSHIFILGINENS
                     YNNDKNTKNLISSLNSYKVTICWLGYGIENLLEHKKYNLDYVGKTNNIVSVNYRGKSY
                     NLDEHYVFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKTFDKGRIFVRIEDVHAFREPKNLVEIADYLSSKNIPFTIALIPAYVNPK
                     NHKVITLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLNGLRVCIENGIYPLAFEAPHYAMESEGYKELKKYFSTYMGQHQNND
                     KKFSTNTYPYIIRDTEEFNIFIPENLGYIDPEDKFTFQNIKENLDKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDKDLDE
                     ITKSDTRFKYISNISKILIFI"
BASE COUNT         7291 a         1902 c         3232 g         6209 t
ORIGIN      
        1 ctaaactatc tatgaaatat gaaatacttg aaaaagaaat aattcataag gaagaattaa
       61 gacttagtaa tgagtgttat aaaattattg ttgaacagac tgattctgtc gttttcgaat
      121 ggaatatcaa agaaaataaa tcatttgtat cgcaggcttg gactgaaaaa tttggatata
      181 acaatgcatg taagaatatt tttaaagaaa ttaaagataa agacttagtt cattctgaag
      241 ataaagctat atttgaaggt tttcttgaaa gtattaaaaa aaagaatata cacagtcaag
      301 cagtatatcg tttaaaaaaa tctaatggtg aatatatttg gtgtagaaca tcaattacaa
      361 gcatttataa tgatgaaaat gaacttttaa gagttgtagg agtaattgta gacgtagata
      421 gtgatataaa aaaatatgaa gagttaagaa ctagagcaga aagtgactca ttgaccaata
      481 tatacaataa aggtacattt gaaaaattag tggaagaaac tatagttatg aatacaggtg
      541 ataaaaaaga tgcattattc attattgatt tagatgattt taaagaaata aatgataatt
      601 ttggtcatcc atttggtgat tttgtactaa aaacatttgc tgataagata caagctagtt
      661 ttggtaataa agacttagtc ggaagaattg gtggagatga atttgttgta tatatgcaag
      721 attatgttac agaagtaaat ttgcataaaa aagctaaaga attaaataga gtactttcgg
      781 ataattacac tgatttgagt tttagttttg attcttctgt cagtataggt attgcaaggt
      841 atcctcaaga tggaacttca ttttttgaat tgtttaaaaa tgcagataga gcactttata
      901 gcataaaagc atcaggtaaa aattcatatt gtttatttga agaagaacta tatgtacagt
      961 gaatttgaat ttagatttta tgtgagagta agatttatat atacttgtgg ctgtctgatt
     1021 tataaaatat gttactttgt atatttttat atgtttcagt aaggttaatt aacataagca
     1081 aaggtgtaag taaatttata ttagtttaag tttacttaca cctttataaa aataaatttt
     1141 gtaaatttaa acagttggtt ttataaggat ttttatttat tttaatatct tagatattcc
     1201 tttttgtatt ccttagagaa aataaataat gaaaggagta cagaaaaaat taaacatcct
     1261 aatataccac ttgaattaag tcttaaagca ttaaagttta aaaaagcatt atttaaatcg
     1321 gtatccaaaa gaaaaggatg ctttgatttg ctatatatgg aaaaattaaa aatatattca
     1381 taatcaaatt tataaaatta atatctttcc atcctaacat tacatttact tagattaatt
     1441 attattataa aaataaaaat acaaataata gattcattta cattcttaaa tgattaaagc
     1501 tctttaccct ttaaacatgc ataacatatc gttataattc cagtaaataa gactaaaatg
     1561 cccattccta aaattgcagt ttcatcatct attactccaa atgcttttaa agtaacttat
     1621 ttcgctttgt ataataataa tttgtctctt tttatatttt aacttctgct gagatttgag
     1681 ttagatattc gttagaatct cgcacactta tatcatatag aagatattct tcataaacaa
     1741 aatccccaat acgtaaatta ttctgattaa aaaaatttaa taacttttca taagccttgt
     1801 aaatagtttc ataactacct ttatgataag cagttacata aagtcccttt ggtttgattg
     1861 atacaggata tttcttgtac tctttattaa cttttgtaaa taaatatgaa tatgattcaa
     1921 agtctttatt aattatatct tcacctttaa tgattgagcc aatcgtacca tagtcactca
     1981 attcatagtt gtccataaag ttaatacatt catataaaaa attttcttcc tcatctccta
     2041 aaaactgttc tttatatgta ataggtgttt tgaccaagta ctcttcctca tgttctttta
     2101 aagtaatagt attcgcatct atattacagg catttttagt gaatgaaata gtagattcca
     2161 ttagagcttg aatattattt agtttttcaa tttcattttt aatatcaatg gttttctttt
     2221 ctaaaagctc aattagtaaa ttaggtgttc ttttgtctat ataagcttta atttctttta
     2281 aaggcatttt tacttcccta agtgaagaaa ttataccaaa aatgctaagt tgatggtatg
     2341 agtagtatct atatccattt tctttcttta attctggtga gaaaagacct atatcatcat
     2401 aatggaaaag tgttttttta ttgattccac aaatctttgc aaattctcca gttgtaaaat
     2461 aattttttga aacttgactc ataattataa ttcctccttg actatcctgt tacagtatag
     2521 tttatcatag tattttgtaa aggagtgtga ttatatgaaa aaattaattc attttttaaa
     2581 accatataga gttttaattg ttgtagtttt gatatttacg tttttacaaa cacttggaac
     2641 tttgtatata ccaacactta cagcaaatat agtaaacaat ggtgtagtaa agggagatat
     2701 agattatatt gtaaaaacag gtttaataat gatgatagta gctggtataa cagctttatc
     2761 agctgtgtta gtttgtaaag tatcagcaaa tctttcatct ggattttgta gagatattag
     2821 agaagcagta tttgtaaaat cacaagattt atcaataaat gattttaata atataggtac
     2881 agcatcaatg attactagga gtactagtga tattacttta ataggtcagt ctgtgtttat
     2941 gtttattcaa ttggtattac cagcaccaat tataactgtt tctggtctat tcttagcata
     3001 ttctatagat aaagcaatga caattattat tgttgtagta atgtttttat tcatgctttc
     3061 agcattttta gttggtaaaa agcttataaa gttgtttaaa atgatgcaaa taaagatgga
     3121 caatatgaat agggtattac gtgaggtagt aactggagta agagttataa gagcttttaa
     3181 tagggagcat tttgaaaaaa agagatttga tagaactgca atagattatt ctgaaacagc
     3241 aatttcaata aataaagtat ttgcagtact tatgcctatt gtaatgttaa taatgaattt
     3301 aggtatagta agtattattt ggtttggtgg gatgagagtc agtaatggaa atatggagat
     3361 aggtcatata atggcactta ttgaatattg tatcttaatt ttattctatt taatcatggg
     3421 agtaatggta tttatgtaca tacctagagc aggtgcatgt gcagatagag taaatcagat
     3481 attagatata gaacctgaaa ttgtagatgg aaatggtcgt aaagatactg tctcagagag
     3541 gggacattta gtatttaaaa atgtaacatt ttcatatgca caatcagaag aacctgtgtt
     3601 aaataatata acatttgaag caaaatctgg agaagtaact gcaattatag gaagcactgg
     3661 ctcaggcaaa tctactattg caaatataat accacgtttt tttgaaattc aatctggaga
     3721 aatatctata aatggtcagg atgttaagaa gattcctcaa aaagaactta gagataagat
     3781 tggatttgtg ccacaaaaag cttttttatt tagtggaaca atagaagaaa atataaggta
     3841 tggaaaagaa gatgcaagta ttgaagaaat aaagcatgct gcaagtatag ctcaagctga
     3901 tgaatttatt tctgatatgg aagacaagta tgactcattt gtagcacaag gtggaaataa
     3961 tttgtcaggt ggtcaaaaac agagaatatc cattgcaaga gcgttagtta gaaagcctga
     4021 agtatatgtc tttgatgata gtttttctgc attagatttt aaaacagata aaagacttag
     4081 aaaagcgttg aaaaatgaaa tcaaagattc atcagctata attatagcac aacgtataag
     4141 tacaatcatg gatgctaatc agattatagt tttaaatgat ggaaaaattg taggtattgg
     4201 aaaacataaa gatttacttg aaaattgtga agtttataag caaattgcgg attcacaact
     4261 tagtaaagaa gaacttgcat aaaatgaaga attaatctga tatttggagg tgtatgatat
     4321 gagtgaaaaa agaatagatg aacaagatat agaagtactt agttttgaag atggcatgtc
     4381 agcagaaaaa gttaaggatg caaaaaaaac tactaagaga ttattaaaat atatggcaaa
     4441 acaaaagttt aaaatattaa ttatttttat ttcagtattg ataagttcag cgcttacagt
     4501 tttagcacct atggttatgg gaaaagctat tgaccaacta tttaatggaa taaaaactgc
     4561 agtccaaaca ggtacaaaat tcagtgtgaa ttttagtact atggggggga tagtatcaat
     4621 acttctaggg ttgtacttaa ttagtgcagt atttatatat attcaacagt atattatgtc
     4681 aggagttgca caaaatctag ttcttagcat gagaaaagat ttaagtgata aactcaataa
     4741 acttcctctt aagtactatg attctcataa aaagggggaa acacttagta tagtaacaaa
     4801 tgatttagaa aaagtagcag atagtttaca agaaggatta atgcaactta ttacagcagt
     4861 agttacagta gttggttcta ttgtaatgat gataagtata agtgtaccac ttacaatagt
     4921 atcagctata acattacttg tttcattggg tattactgtt gtaattgcaa gaaaatcaca
     4981 agaaagattc tctgaaaatc aaaaggcact aggagagtta aatagcaata tagaagagat
     5041 atttactggt caaatagtgg ttaaagcatt tagtaaagaa aaggatacta taagaaactt
     5101 taaaatatta aatcaaaatc tttataatgc aagtagaaga gcacagtttt cgtcatatgc
     5161 aatatctcca attattagat ttataaacct aattggctat gttattatag cagttgtagg
     5221 tgggatattt gcatcaactg gagcaatgac tcttggtagt atacaagcgt ttattcaata
     5281 tgtaaatcaa gcatcagagc ctactacaga aatatcttat attgtaaata tgcttcaagc
     5341 agcaatagca tctgcagaga gagtttttac agttatggat gaggtggaag agataaagga
     5401 tgaagaatct tcaaaggtta ttagcatgcc taaaggtaaa gtacaatttg agcatgttaa
     5461 atttggatat agtgatgatt ttattcttat gaaagatatt aatatcaatc taaatgcagg
     5521 agacaagatt gcaattgttg gacctacagg agctggaaag acaactcttg taaatttact
     5581 tatgagattt tatgagatac aaggtggaag aattactatt gatggtgtta atataaaaga
     5641 cttaaagcgt ggagaactta gaactatgtt tggtatggtt cttcaagata catggctgtt
     5701 taatggaagt ataaaagaaa atattgcata tagtaagtca gatgccacaa tggatgaaat
     5761 tgtaagagca gcaaaatcag caagagtaga ccattttata aggactttac cacaagggta
     5821 tgacactata ttgactgagg atgcttctaa tctatctcaa ggtcaaaagc aacttctaac
     5881 aattgccagg gcaatacttt cagacccatc agtattgatt cttgatgaag caacatctag
     5941 tgtagatact agaacagagg tagaaattca aaaggcaatg aataacttga tgaagggaag
     6001 aactagtttt gttattgcac atagattatc aactattcga gatgctgatt taatattagt
     6061 aatgaaagaa ggcactatta ttgaacaagg aagccataag gaacttattg aaaagaaagg
     6121 attctatgaa gaactttata atagtcaatt ttcaagtgaa tatgatgaag aagttgtatg
     6181 attatcaagt tttaggcaac taaatgattg ataaatatta agttaaatat agtaacatgt
     6241 aaggttatat ggaataagag tatttctcta tttcatataa ccttttttat ttatcaaaat
     6301 aagataaaat tttctttcta aattagattg aagaaagtat ttatcaatat aaaagtaaaa
     6361 taatcattat tattagtgaa gtaaatattg tttgccacat atatgccata aagatgcact
     6421 tattttacgg agatttaaca aagtagtgta aagtatactc taaatataaa ataaatcaaa
     6481 tagagttaaa taaattgaga ggtgatataa atagtgaata aaaaattgaa ctatagattt
     6541 gaaatgaagc acaaaataac tgaagcagat gtgttagctt taaaatcaag actctatcca
     6601 ataatgaaga aagatgaaaa tgcatctaaa gatggaaaat atcttattag gagtttatat
     6661 tttgatactc ctgaagataa agcactttta gataaattaa atggcgttgc aataagagaa
     6721 aagtttagga taagatttta taataataac tgctcttata taaggttaga gaaaaaaatc
     6781 aaacattaca acatgacatc aaagctatca actaatttaa ccaaaaaaga agtaataaat
     6841 atactaaaca atgatattga atttctaaaa gagtcgacaa attgtttatt aagagaattt
     6901 tatttgaaat taaaatgtga aagattagag gcaaaaagca tagttgatta caatagagaa
     6961 gcttttattt atccagttgg aaatgtaaga gttacaatcg atagtgatat taaaacttct
     7021 gtaaattcga tagatttatt taataaagat ttgccgactg tttcggtaat tgatgagaat
     7081 atgactgtat tggaggttaa atatgatgaa tttataccag attttataaa ggatttaatt
     7141 caaattaata agactacttc tacagcagtt tcaaagtatg cttcaagtag attatatatt
     7201 taagaataaa ggctatgatt tatataaaga tatacataaa taaggttaaa aaacaaatag
     7261 gttaaaaata aataaaataa aaaataaata agttaaaaat aggaaggatg attttaatta
     7321 tgacatttaa tgatattttt aaatcaagtt ttatagaaaa cgtatcaggt ttttcatttg
     7381 tggacagtgc tttagcacta ggttcagctt ttttagtagg tttgtttata tatatggtct
     7441 ataaaaagac ttatatggga attatgtatt ctcgaccatt caatgtgtcg cttgtagcac
     7501 ttacaatgct tacaactttt gtaatattgg cggttacttc aaatgtagtt ttatccttag
     7561 gtatggttgg tgctttatct atagtaagat ttagaacagc aattaaagac ccaatggatt
     7621 tagtatttct attttggtca ttgggttcag gtatagtttt aggagcaggt ttgattccct
     7681 tagctgtcat gggttcaata attatgggat tgattctaat attcttttca aataaaacaa
     7741 tatctgaaac tccatatata ttgatggtaa attgtaataa tgaagattca gaagatatag
     7801 caactgataa aattaaaaaa gtatttacta aatatcaaat aaaatcaaaa agtgttacac
     7861 cagaaaaagg aatagaatta gtgtttgaag taagaatgaa atatggagag acaagtctta
     7921 taaatgactt gagtcaagta gatggagtta ctaatgcagt tcttgtaagc tataatggtg
     7981 actatgtagc atagagagga gtaatctttt atgaaagata aaaaatttac ccttcttatc
     8041 tctattatga ttatattttt atgtgctgta gttggagttt atagtacatc tagcaacaaa
     8101 agtgttgatt tatatagtga tgtatatatt gaaaaatatt ttaacagaga caaggttatg
     8161 gaagttaata tagagataga tgaaagtgac ttgaaggata tgaatgaaaa tgctataaaa
     8221 gaagaattta aggttgcaaa agtaactgta gatggagata catatggaaa cgtaggtata
     8281 agaactaaag gaaattcaag tcttacatct gtagcaaata gtgatagtga tagatacagc
     8341 tataagatta attttgataa gtataatact agtcaaagta tggaagggct tactcaatta
     8401 aatcttaata actgttactc tgacccatct tatatgagag agtttttaac atatagtatt
     8461 tgcgaggaaa tgggattagc gactccagaa tttgcatatg ctaaagtctc tataaatggc
     8521 gaatatcatg gtttgtattt ggcagtagaa ggattaaaag agtcttatct tgaaaataat
     8581 tttggtaatg taactggaga cttatataag tcagatgaag gaagctcgtt gcaatataaa
     8641 ggagatgacc cagaaagtta ctcaaactta atcgttgaaa gtgataaaaa gacagctgat
     8701 tggtctaaaa ttacaaaact attaaaatct ttggatacag gtgaagatat tgaaaaatat
     8761 cttgatgtag attctgtcct taaaaatata gcaataaata cagctttatt aaaccttgat
     8821 agctatcaag gcagttttgc ccataactat tatttatatg agcaagatgg agtattttct
     8881 atgttaccat gggattttaa tatgtcattt ggtggattta gtggttttgg tggaggtagt
     8941 caatctatag caattgatga acctacgaca ggtaatttag aagacagacc tctcatatcc
     9001 tcgttattaa aaaatgagac acacaaaaca aaataccata aatatctgga agagatagta
     9061 acaaaatacc tagattcaga ctatttagag aatatgacaa caaaattgca tgacatgata
     9121 gcatcatatg taaaagaaga cccaacagca ttttatactt atgaagaatt tgaaaaaaat
     9181 ataacatctt caattgaaga ttctagtgat aataagggat ttggtaataa agggtttgac
     9241 aacaataact ctaataacag tgattctaat aataattcta atagtgaaaa taagcgctct
     9301 ggaaatcaaa gtgataaaaa agaagttaat gctgaattaa catcaagcgt agtcaaaact
     9361 aatacagata atgaaactga aaataaaact acaaatgata gcgaaagtaa gaataataca
     9421 gataaagata aaagtggaaa tgataataat caaaagctag aaggtcctag gggtaaagga
     9481 ggtaagtcaa taccaggggt tttggaagtt gcagaagata tgagtaaaac tataaaatct
     9541 caattaagtg gagaaacttc ttcgacaaag caaaactctg gtgatgaaag ttcaagtgga
     9601 attaaaggta gtgaaaagtt tgatgaggat atgagtggta tgccagaacc acctgaggga
     9661 atggatggta aaatgccacc aggaatgggt aatatggata agggagatat gaatggtaaa
     9721 aatggcaata tgaatatgga tagaaatcaa gataatccaa gagaagctgg aggttttggc
     9781 aatagaggag gaggctctgt gagtaaaaca acaacatact tcaaattaat tttaggtgga
     9841 gcttcaatga taataatgtc gattatgtta gtaggtgtat caagggtaaa gagaagaaga
     9901 tttataaagt caaaataaga ttaaaattga atataaataa ttttaatact gttaagtcta
     9961 aatatttact tagcagtatt tttttagaaa ataatgtgtt tgattaataa tataaggtaa
    10021 taaattgata aaaattaaat acagcatatt aataatacat aataaagtaa taaaaaaact
    10081 gtttaagtat aataacttat atttagacag tttttttcat ttataaataa tataaatgaa
    10141 attgaaaaca tttgaaggat agaaattggt tggataaatg tataaattac ttcaccaaaa
    10201 aataatgaca agagttgtaa ctaagttgta ataaaatggt agttatttag cataaaataa
    10261 tgtatcatag aagtatatta taaaattaat aaaataagat ttttgtaaga aaactgctgg
    10321 cttttgatat ttagagtgag tagttaaatt atgtttagga ggggtagaat ttgttgcaaa
    10381 aagtattatg gaaattttta aagctagtag tcggtttatt tatatgttca gttggtatag
    10441 tattgacgat aaattgtaac cttggattat ctccctggga tgtatttcat caaggacttt
    10501 caaatcatat aggaataact ataggaactg cttctataat tgtaggctct atagtagtta
    10561 ttgctgatgt cgttcttgga gaaaatgtag gatggggaac tgtttttaac atgctactaa
    10621 ttggattctt tatggattta cttttatata gtaatttaat tccagaggct gatagtttat
    10681 ttgtaggaat aattatgttg atattaggat tggttctttt gtctgttgga atggtatttt
    10741 atatgggaag tggtttagga agtggaccta gagatggttt gatggttgca attcaaaaga
    10801 aaacaggaaa atcacttaaa ttaataagag gtactataga agttggagca ttaatagtag
    10861 gatttttatt aggtggaaaa gttggtatag gaactataat aagtgcattt ggattggggt
    10921 atttcacaca aatggtattt ggcttattta aattagattg tagtaagatt aaacatagat
    10981 ttatagtaga tgatataaaa tttatcaaag tgtatatgag tggtgagaaa aaagctgctg
    11041 ttcaaaatat agttaagtaa tttaagaata aattcaacga aatgttaagt attttaaatt
    11101 aacattttat ttagatggat aaattgaata ttaaaagaat attaaaatat gaggattgct
    11161 agaacactat aaaatataga tttctagcaa ttttttattt gttcaatgtt tttttagtac
    11221 tagaagtctt attctctatt taatgaatga attaatttat aattagagat actaaacttt
    11281 atagatatta atataaacac ctttaaactg tgtattttcc aaagccttta aaatgcttgt
    11341 atttattcta aataaaaaaa taaaaaaatg tcaaaaaaac tcttgtatta tatccaaatt
    11401 ttatatataa ttacctatgt tgtttagaaa ttttaaactc aatgtttagt aaacaaaatg
    11461 tttagtaaaa taaaacagaa actaggaggt gcaacatgga tataggtgaa aagataaaaa
    11521 gattaagaac agaaaaacaa ctgacccagg aagagctagc taatagatgt gaattgtcaa
    11581 agggatttat ttctcaatta gaaaataact taacatcacc atccatagct acccttatag
    11641 atatacttga aatactaggt acaaatttaa gggaattttt taatgaaata gatgatgaaa
    11701 gaatcagttt tacaaaagaa gatatgtttg aaactgaaga tgaagattta aaatataaat
    11761 taaagtggtt aattccaaat tcacaaaaaa atgaaatgga gccaataata ataacattgt
    11821 atccaggagg acagtataaa gaagaaaagc cacatgaagg tgaagaattt ggatatgtat
    11881 tagcaggttc aatatatgtc catataggcg aaaagaaaaa taaagtaaaa aaaggagaga
    11941 gtttttactt tagaccaaaa gcaaatcact atatatcaaa cgaaggcaaa actacagcaa
    12001 aagtgatttg ggtaagtacg ccaccatcat tttagaatag aggtgtttaa taattggtag
    12061 aaaatataat agaattaagg gatatatcta aacattatga ggaacttact gttttagata
    12121 atttcaattt agatataaag aaaaatgagt ttttaacatt acttggacca agtggatgtg
    12181 gaaaaactac aacattaaaa ataatagcag gatttgagta tgctgatgat ggtaaagttt
    12241 tatttgaagg taaggagata aataacttgc caccatatga aagacaagta aacacagtat
    12301 ttcaaaaata tgctttattt ccacacatgg atgtttatga aaatgtagct tttggattaa
    12361 aaattaaaaa gactccaaaa gatgtaatag atgctaaagt aaaagaggtt ttgaaacttg
    12421 ttgcactaga aggttttgaa agacgacaag ttgaatcatt gagtggagga caacaacaga
    12481 gaattgcaat agcaagagct ctagtcaatg aaccaaaggt attattacta gatgaaccac
    12541 ttggagcact tgatttaaag ttaagacaag agatgcaaat agaattaaag agaatccaaa
    12601 aaaaattagg aataacattt gtttttgtaa ctcatgacca agaagaggct cttactatgt
    12661 cagatactat tgttgtaatg tataagggca aaattcaaca aatgggaaca ccacaagata
    12721 tatacaatga acctaaaaat tcatttgtag ctaaatttat aggtgaaagt aacatatttg
    12781 atggaattat gatagaagat tataaagtta atttctgtaa tagagatttt gagtgtgttg
    12841 ataaaggatt cgaaaaaaat gaaaatatag aagtagtaat aagaccagaa gatataaaaa
    12901 tggtaaagcc agaagaagga atgttaaagg ggaaagttac atctacagtg tttaaaggag
    12961 tgcattacga gatagaattg aatgaaaatg gaagattgtg gatacttcat aataccaaaa
    13021 atgctgaggt tgggactgaa ctaggcatgg atatatatcc agaagatatc catataatga
    13081 gaaaagagaa taactaagat gaaaagaaaa tcttttttag catatccata tgtagtttgg
    13141 agtgcgatat ttgtaataat tcctttaata ttagtggtat tttttagttt tacaaaagaa
    13201 tcaggtggag gttatgcctt tacacttgag aattataaag aagtaattga ccctatatat
    13261 atgaaagttt ttgggcgttc tattctttta gcaggaggag ctacattaat atgccttata
    13321 gttggttatc cagtggcata tataatttca aaggctcgtg taagtagaag aggttcatta
    13381 atattattgt ttattcttcc tatgtggatg aactttcttt taagaacata tgcatgggtt
    13441 gctatattag gaaaaaatgg acttttaaat acatttttag gttggtttgg aatacaacca
    13501 ttagcaattt tgtatactaa ttttgctata cttttaggta tggtgtataa ctttttacca
    13561 tttatggttc ttccaatata tacagcacta tcaaagatgg ataatgattt gataaacgct
    13621 gctcatgact tgggtgcaaa taatatgaca gtttttagaa aaattatatt tcctttgagt
    13681 ttgccaggtg taatgtctgg aataactatg gtatttatgc cagcagtcac tacttttgca
    13741 atatcaagac tgttaggtgg aggtaaaata atgctggttg gagatttgat tgaacaacag
    13801 tttacagttg ttggagattg gaactttggt tcagctatat cgatatttat gatgatagta
    13861 atattaatat ctatgtctat aatgtcaaaa tttggagatg aatctgacaa agaaggcggt
    13921 gggttactat tttaaaatta aagaaaataa cttctaatat atatttagca ttagtattct
    13981 tatttttgta tgcacccata tttgctttgg tactattttc tttcaatgat tcaaaatcaa
    14041 tggcaagatg gaatggattt acatggaagt ggtatggtca attacttcaa aatgagagta
    14101 taatgagtgc tttatattat actattgtaa tagctatatt agcgtctgta atatctacaa
    14161 tagtaggaac tataagtgct ataggaatac ataagatgag aggtaagagt aagaaattaa
    14221 tactaaatgt aaactatctt cctattttaa atacagagat agttacagca gtagctctta
    14281 tgagcctgtt tgtatttgta aaaatggaat ttggatttac aacaatgcta ttggcacata
    14341 taatgttttg tttgccatac gttatacttt cagttttgcc aaaaatgaag caattacctg
    14401 ataatataga agatgcagct atggacttgg gagcaacacc tatatacgct cttagaaaag
    14461 taattttacc acaaataaaa ccaggtatag tttctggatt tttaattgca tttactatgt
    14521 caatagatga ctttataata agtttcttta atgctggaaa tggtgtaagc aatctttcta
    14581 tagaaatcta tggaatggct agaagaggta taaaacctga aataaatgca ttatcaacaa
    14641 taatgtttgc agtggttcta ggtttacttt tactagctaa taaaaaagaa tctatagtaa
    14701 gggggattaa ataatgatta agtttaaaaa aacaatatcc cttatagctg taggtatgat
    14761 gacagttact ttatttacag gatgtaataa agcaactgat tctacaaaag ttttaaatgt
    14821 atataatgtt ggagattata tagatgagtc tcttatagat aagtttgaaa aagaaacagg
    14881 aatagatgtt caatattcaa cttatgatac taatgaaatg atgtatcaaa aagtaaagag
    14941 tggtagtaca cactatgatt tagtatttcc ttcagactat atggtagaga aaatgaaaaa
    15001 tgaaggtctt ttggaaaaat tagattttaa gaatatacct aatatgaaat atttagataa
    15061 gagtttttta aatcctgtat acgacaaaac taatgaatat agtgttgcat atatgtgggg
    15121 aactcttgga atattgtaca ataagaaaga agttaaagac cctatggata gctggaatat
    15181 actttggaat ccaaagtata agggaaatat aatgatgttt gactctgtta gagatactat
    15241 agggataact cttaaaaaat taggatatag catgaatagt gtaaatccaa aagaaataaa
    15301 tgaagctaaa aatcttttaa tgaaacaaaa ggatttagta ttggcttatg taaatgatga
    15361 aggtaaggat agattgcttg gtggagaagt ggcaatgggt atgctgtatt ctggagatgc
    15421 agttacgcta atggagcaaa atcctgacct tgattatgct atacctaaag agggaactaa
    15481 taaatgggta gatgctatgt gtgtacctac aacagcacaa aataagaaag aagctgagct
    15541 gtttataaac tttttattag acccagagaa tgcaaaagta aatgctgagt acattgggta
    15601 ttcaacacct aatacaggag cactaaaatt attagaccca gaaataactc agaatcctgt
    15661 tgcatatcca tctaaagaag tacttgataa atgtgaaact tttgaagata ttggtgaaaa
    15721 tataaaatta tatgacaagg cttggataga gttaaaatca aaatagggtc ttgttggttt
    15781 aagtaaattt acttaataaa tacttaataa aactgttctt ttttagaaaa tttattttct
    15841 aattattgaa cagttttatt ttttgtttag gtcatgtttt tattttgagt ttatttttat
    15901 gagaatttaa agtacagtaa gtttcattga ttactatttt tataataata actataaaga
    15961 ggttgtctcg aaattgagat aagcctcttt ttcattgttg aaatgatgaa aacatgtttg
    16021 atttcataaa aaaagagtga ttcatgagct aaagaatttg ctttgagaca gtatttttta
    16081 ttaagttata ttcatatgca atttaaatag tttattaata aatgaaaact tatttgtata
    16141 atgattttaa taataattag aaaaaatggg caacttaata gaataattgg aggtgtaaat
    16201 ttataaaaaa tgaataggat aaataaaaaa atagatttat taatattggc tttgctcgtt
    16261 tttatatttt taattgttgg aatagtaata ctatcgatta ggacagaaaa taaattgaat
    16321 gtgttcataa tgttagcaat aatttttttt ataataatgt taacttattt atcaaattca
    16381 gtagtggggt tgataacaag ttcaataatt atatttatgt atacatccta tattttatat
    16441 aacaatatta ctcacaatat ggatgttgaa tttatatcat atatgtggat aatagcaaca
    16501 ccagtatctt caattataat gggtaatctg aacaaaagca taaatgaatt gcaaaataca
    16561 aataaaaaac tatctgaaca gtataaggaa ttagtgacta ttgatagtga aactggactt
    16621 agaaatttaa agatttttta taatgatgta aatatggaga taagtaaatc tattagacat
    16681 aatactgatt tttctcttat gatagtaaaa ttaccatact acggaaacct acagactata
    16741 tttggtgaaa acaaaactaa taaaatagta aaatatattg gttcaaatat tatagaatgt
    16801 acaagaaatg aagatataat ttatagttta caaaaagata tgatagggat actaatgcca
    16861 aatacatctt tggaaggttc gaaagttgtt aaagacagaa taaagaaaag gataaaagaa
    16921 ttaaatttag atttaaacaa taggggaaaa tatgtaaata tagatgtcaa aattgcattt
    16981 ttacaatata agagtagttt tggagatagt ataaatttta agaatatagt tgaagaggaa
    17041 cttcaatatg atgtttaaaa tatttaataa aagtttatta aaattagtaa ttgtattatc
    17101 aatagtactg acaatatcaa attttagctt attttcatat gcatcagaaa ttacttccag
    17161 cacagataag gtattaatca tatatgattc taagaaagaa acagcttata atagagatat
    17221 tttaaatatt atgagaactc tattgggaag atttagttca gatatagagc tattaaaatt
    17281 gagtaactat gatggtgaga taaatgaaaa ttattacagt catatattta ttttaggaat
    17341 caatgaaaac tcatataata atgataaaaa cactaaaaac ttgattagtt ccttaaattc
    17401 atataaagta actatatgtt ggttaggata tggtatagaa aatcttttgg aacataaaaa
    17461 atacaattta gactatgtag gaaaaacaaa caatatagtt agtgtaaatt atagaggtaa
    17521 atcatataac ttggatgaac attatgtttt taacattgta gaatcaaaag atacaagtaa
    17581 taaagtaata ggaagtatta atgatacctt aaataagtat ccatatataa taaatgataa
    17641 aaatcttttt tatgtatcaa aattagattt agatggagtt ttattttata tattttgcga
    17701 ttcacttaat gatattttta atattaagac gtttgataaa ggacgtatat ttgtaagaat
    17761 agaagatgta catgctttta gagaaccaaa aaatcttgta gagatagcgg attatttaag
    17821 tagtaagaat ataccattta cgattgcatt aataccagca tatgtaaatc ctaaaaatca
    17881 taaagtaata actttatcag aaagccctga aattgtcaaa gcaataaaat atatgcaaga
    17941 taaaggtgga actgtgatat tgcatggata tactcatcaa tacaagaaag aagaagtttc
    18001 tggagaaggg tatgaatttt gggatggtaa aaaagatgaa cccttaaaag aaaatatgaa
    18061 gatatttgtc aaagatagag ttttgaatgg tcttagagta tgtatagaga atggaattta
    18121 tcctcttgca tttgaagcgc cacattatgc aatggaatca gagggatata aagaattaaa
    18181 aaaatatttt tctacttata tggggcaaca tcaaaataat gataaaaaat ttagcacaaa
    18241 tacatatcct tatattatta gggatacaga ggagtttaat atatttatac ccgaaaattt
    18301 aggatatata gacccagaag acaagtttac ttttcaaaat ataaaagaaa atttagataa
    18361 attatctatt gtaagaggtt ttagtggagg gttcttcttt cattcatatt taaacataga
    18421 gtatctaaaa aacacaatag aatatttaga aaaacagaat atagaattta tgaatttaag
    18481 agattttaat aattgggtaa aagttgatga aatacaaata agaaataatg gagatgaaat
    18541 tatagtcaac tatgataagg acttagatga aataactaaa agtgatacta gatttaaata
    18601 catatccaat attagtaaaa ttttaatatt cata
//
LOCUS       DAMJWO010000083        18578 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.085, whole genome shotgun sequence.
ACCESSION   DAMJWO010000083 DAMJWO010000000
VERSION     DAMJWO010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18578
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.085"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(266..1045)
                     /locus_tag="PC366_002982"
     CDS             complement(266..1045)
                     /locus_tag="PC366_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HDF2578479.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVHPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINGFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
     gene            complement(1058..1792)
                     /locus_tag="PC366_002983"
     CDS             complement(1058..1792)
                     /locus_tag="PC366_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HDF2578480.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            complement(1821..2024)
                     /locus_tag="PC366_002984"
     CDS             complement(1821..2024)
                     /locus_tag="PC366_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578481.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQNINYTVKSIEGKKDKEKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            complement(2027..2584)
                     /gene="frr"
                     /locus_tag="PC366_002985"
     CDS             complement(2027..2584)
                     /gene="frr"
                     /locus_tag="PC366_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HDF2578482.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDTLLSKKEKDIMEV"
     gene            complement(2610..3314)
                     /locus_tag="PC366_002986"
     CDS             complement(2610..3314)
                     /locus_tag="PC366_002986"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HDF2578483.1"
                     /translation="MDKPMYKRVLLKLSGEALAGERGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            complement(3399..4310)
                     /locus_tag="PC366_002987"
     CDS             complement(3399..4310)
                     /locus_tag="PC366_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HDF2578484.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            complement(4389..5102)
                     /gene="rpsB"
                     /locus_tag="PC366_002988"
     CDS             complement(4389..5102)
                     /gene="rpsB"
                     /locus_tag="PC366_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HDF2578485.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            complement(5309..6493)
                     /locus_tag="PC366_002989"
     CDS             complement(5309..6493)
                     /locus_tag="PC366_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDF2578486.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADGKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHICKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDHYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMVVNKNEKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGMKELEVTLKAKDELYTILKDDE
                     SIKSEVKIKNIEYPVKKGDTMGVIKYYTSSGDLLGSVDIVSNNSIDNVSLKTKLKMKF
                     AN"
     gene            complement(6597..7655)
                     /locus_tag="PC366_002990"
     CDS             complement(6597..7655)
                     /locus_tag="PC366_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HDF2578487.1"
                     /translation="MNCKWISKIDERKKCHREADSSGYCIFHKENKSDEEIQLMMDTI
                     HKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FRDKVLFNGCIFLENCDFNRTIFSKNYINDRIFEKVKFKGPDLVVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMK
                     RSNYPTFSDYLVEKFFDQIARYTTGYGEKPWNILLVIIAIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFKMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            complement(7869..8513)
                     /locus_tag="PC366_002991"
     CDS             complement(7869..8513)
                     /locus_tag="PC366_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2578488.1"
                     /translation="MEQHSKVGNFGDLLKVLLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQRPNINHLEKMAIHLNINLEELLKASGYEFRNSNNQIFNADSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
     gene            8698..9321
                     /gene="ytaF"
                     /locus_tag="PC366_002992"
     CDS             8698..9321
                     /gene="ytaF"
                     /locus_tag="PC366_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HDF2578489.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFLLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLELNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLLGCLLGNMFVKNVNLNLSWLSGLILLVIGFMKIC"
     gene            complement(9384..11294)
                     /locus_tag="PC366_002993"
     CDS             complement(9384..11294)
                     /locus_tag="PC366_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDF2578490.1"
                     /translation="MNSNTFERLQLNEVKDLIKIHCVSSLGKNLIDKLTPSGNIGVVR
                     RKLAENKEARKIIENSNHIPLEGLFNAGSTIDKIEKGMIIEPVELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKSIEDEINYCIKSNKVDSNASKELKKIRRNIEIT
                     EGKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVNGTILDTSSKGNT
                     VFIEPISVSNLSTELTMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMVF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMSLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNIEDKNSSEVILSYTDYNVGDKVKLLDEDDFGIVYKPMDKFN
                     NVEVLFNDNFISVNIKRLQLSIKASELYPEGYDLDVLFTSFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(11831..12898)
                     /locus_tag="PC366_002994"
     CDS             complement(11831..12898)
                     /locus_tag="PC366_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HDF2578491.1"
                     /translation="MSNIKIIASNKCWIEDIARKQLEDISKLNGILRVVGLPDLHTGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGVLKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFVEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYDKDGLEVESEKAIDYIKKHDNALMWAERNREAISKKIMQSIGTSEDVET
                     IFSINHNFIEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTEISLYSLSH
                     GAGRKWSRSVCKSRLKSKYSKDTIKQTKFKSQIICNDVNLLFQEAPEAYKNIEQIIES
                     LIEYELIQVVATMKPLITYKG"
     gene            complement(13144..14139)
                     /locus_tag="PC366_002995"
     CDS             complement(13144..14139)
                     /locus_tag="PC366_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HDF2578492.1"
                     /translation="MYEEVTWLNFIGNRYEVVNSDDVLEINKIYKARDVFYRRNVLIK
                     VIKHNNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGI
                     GLDELILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDF
                     GITKANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNS
                     EEKMLQSIDKGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKA
                     YIEVEDEKEEEQKQDKVIQVKKEYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            complement(14398..15657)
                     /locus_tag="PC366_002996"
     CDS             complement(14398..15657)
                     /locus_tag="PC366_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HDF2578493.1"
                     /translation="MGRRTTRVSRLGKEKKRSVLIVLAALVLIMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKAEALKAITDKYTPEDLNLTYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLSYTDSVVGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLSGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSSGKVIKKEHISNSSYKELKK"
     gene            complement(15896..16525)
                     /locus_tag="PC366_002997"
     CDS             complement(15896..16525)
                     /locus_tag="PC366_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HDF2578494.1"
                     /translation="MKIVTYNIHKGMDSNNRLTLTKMGLYLKQLDCDVICLQEVLYPQ
                     FLALKAVLNMDGVFATNVKKVNMIYGICTFTTSKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVILCGDFNEKNVFLSMFNDMA
                     ISLNKSYLPTFEKSNSRIDYIFVNKNTELKGYTVEKIYLSDHYPVIGYI"
     gene            complement(16718..16879)
                     /locus_tag="PC366_002998"
     CDS             complement(16718..16879)
                     /locus_tag="PC366_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578495.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            complement(17222..18382)
                     /locus_tag="PC366_002999"
     CDS             complement(17222..18382)
                     /locus_tag="PC366_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HDF2578496.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGTYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGADSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPKFNKWTKCDTSFIDEVTSKLEKENKDNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISKLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALVVTQILHMLA"
BASE COUNT         5861 a         3226 c         1856 g         7635 t
ORIGIN      
        1 ataataaagc taaaaatatc gaaattatta aacaaaaaaa tattttttaa tgatagttat
       61 agtataaaaa atatactcac tacaaatata gtatactatt ataaagtaat acttattctt
      121 ataaaattcc ccaaggtctt ctaaattttt gaacaatgaa aatagccatg taactaataa
      181 ctgcagaata tctctgcatt taaaagttac atagctattt tcattactag caattataga
      241 ttgctctttt aaatccaacc aatctttatc taataaaaaa tttaatcgca ctatatacaa
      301 aaggtgcaac taatataaca ctatcaaatc tatctaatat acccccatga ccaggtatta
      361 tctttccata atcctttatc cctacatatc tctttataga agatgcaaat aaatctccta
      421 attgagctat tacacttcct atacttccta ttatcgctaa ttgaagcaaa tcaatgccaa
      481 ataaatatcc aaataaaata caacaaagtg tacttcctat tattcctcca atagctcctt
      541 ctatagtctt tttaggacta actttaggaa ttagcttatg ttttccaagt aaataaccac
      601 taaaatatgc aaatatatct gtcataaaag atatcacaaa tataagccat acatatatac
      661 tacctttttc aaatccattt atagttataa ttataaaatc taaaaatact cctatataaa
      721 aaactcctaa aaacgtaatc gaaacatcta taacattgtt tttgcccatc aacatataaa
      781 ttatacttgc taaaaataaa ataaaaatta ctgcataagt atattctaat ggtaaattaa
      841 aaatattttt tacagctaaa taaatagaaa ataaatatcc tataatgaat attggatgta
      901 catcttttat tttaaatgcc ttataaaact catgcaatgc aatataaact attgctgtct
      961 cagctatata tagaggaata cctccatata caacaaatag aaataatgga accagagcta
     1021 gtgaagcaat aattcttgta agcataaaat aatctcctta cttaagtcct ccaaatcttc
     1081 tatcccttct ttgatatacg tatatagcct tctgtagttc ttctttttta aaatcaggcc
     1141 aatgtatatc agtaaagtaa aactcagaat aagcaacttc ccaaagtaaa aagttactca
     1201 atctttgttc accacttgtt cttattacca agtctggatc tggtatagac tttgtgctta
     1261 aatagttttt tataatatct tcatcaatat tgtttatatc tattttacca ctttcacaat
     1321 tttttactat atctataaga gcatttttta tatctgctct acttccgtag tttaatgcta
     1381 aatttaagtt aactcctgta ttgttttttg tcagttcctt agctgagttt aattctctta
     1441 tacaagtttt tggtaaagca cttatatctc ctatagcagt tacttttaca ttgttttggt
     1501 gaagttcagc tatttcattt cttaagtatg tagataataa gttcataagt gtgtcaactt
     1561 caagtttcgg tcttttccag ttttctgttg aaaatgcata taatgttaag tgcttaacac
     1621 ctaattttga gcattctttt actatatctc ttatagtttc tactccagcc ttatgtcctg
     1681 cagttcttgg aagaaatcta gcttttgccc atcttccatt tccatccatt ataatagcaa
     1741 tatgagtagg tatgttattt aagtctatat catatataat gttgttattc atattttgcc
     1801 tccaatattg ttctgactcc ttaaactaag gagtcagaaa agtatgtgat tatcagttct
     1861 acactatcac ctatctcaga tatttttata actctaggaa ctacaagttt ttctttatcc
     1921 tttttacctt caatagattt tacggtataa tttatatttt gctcatcaaa atattgtttt
     1981 acctcatcta catgaagacc taaaaggtta taatattttt tcaatattat acctccatta
     2041 tgtccttttc ttttttagat aataatgtat ctatttcttt tataaattta tcagtcattt
     2101 tttgaacttc atcttgtgct ttttttaatt catcttcagt taattctccg cctttttcca
     2161 tctttttaat tttctcattg gcgtctcttc tttcatttct tattctaact ttaaattctt
     2221 ctgcagcttt actagctttt ttagctaatt cttttcttct ttcttctgtt aaagcaggta
     2281 cagaaagtct tataacctca ccatcgtttg atggatttaa tcctaagtct gagttagcta
     2341 tcgctttttc tatttcatgc atagcagatt tatcccaagg agatatcatt aatattcttg
     2401 gttctggtac agatatagca cctatttgat ttattggagt tggagttcca taataatcaa
     2461 ctcttatttt gtctagcatt tgtgcattag ctcttcctgc tcttatagtt ccaaattcaa
     2521 actttaaagc atcaattgtc ccattcattt tctcttctaa ttgcttatgt atttccagtt
     2581 tcataatttt actcctcctt cattcttcat tattttacag tagttcctat attttcgcct
     2641 tttactgctc ttattatatt ctctgttgta agctcaaata cctttattgg aattttatta
     2701 tccatacata aagatgtagc tgtagaatcc attactttta attctttctg tataacttcc
     2761 atgtaactta attctgtaaa tttcttagca tctgcatgta cttttggatc cttgtcatat
     2821 actgcatcaa catttttagc tagcaatata acttctgctt ccatctcagc agcacgtaaa
     2881 gcagcagttg tatctgttgt aaagtaaggg tttcctgttc ctgcaccaaa tataacaact
     2941 ctttcctttt ctaagtgtct aactgctctt cttcttatat atggttctgc aatttgtctc
     3001 atgtctatag cagtttgaac tcttgtagca acatctatat tttctagtgc atcctgtagc
     3061 gccattgcat tcataactgt agctaacatt cctatatagt cagcagtagt tctatccatt
     3121 ccttcactgg ttctgcctct ccagaagttt cctccaccta ctactacagc tacttcaaca
     3181 cctatttctt gtattttttt tatagcaata gcaatatcat taactacatc attatttata
     3241 ccaaaacctc tttctcctgc taatgcttct ccacttaatt ttaacaatac ccttttgtac
     3301 attggtttat ccatcagaaa cctcctattt caatccttca tatccaattt tttctatttt
     3361 ttaaaaaaga gaacacctgc gtgttctctc tttggttatt acttaagttg cttagcaact
     3421 tcttctgcaa agttttcttc tctcttttgt ataccttcac caacttcgaa tctcacaact
     3481 ttaacaactt ttatatcaga acctactgcc ttagcaacat cagcaactaa ttgtttaaca
     3541 gttatatctg gatttttaac gaaagtttgc tctaataaac aaacctcttt taattctttt
     3601 tctaatcttc ctttaaccat tttttcaact atattagctg gttttccttc atttaaagct
     3661 tgttgagtta atacttctgt ttcatgtgct atgtattcag catctacttc atctcttgaa
     3721 acatacttag gattcatagc agcaacttgc atagctacat ctttacctaa ttctaaaact
     3781 ttagcatctc tagcttctgt ttccatttca acaagaacac ctatttttcc accaccgtga
     3841 atgtatccag caacttgtcc attagttaca actttagcaa atcttctaaa gtctaatttc
     3901 tcacctattt ttgcaactct attatttaaa acttcttgta aagttattcc ctctttatga
     3961 gtttcaccta ataaagaagc tatatcttct ttatcagtag ctaatgccat acaagcagca
     4021 tctttaacga acactttgaa gtcttcgttt ttagcaacga aatctgtctc tgagttaact
     4081 tctaccatag aagcaactgt attatcatca ttcatttcta ttgcaactag accttcagca
     4141 gcaactctac cagctttttt agcagctttt gataatcctt tttctcttaa taaatctact
     4201 gctttttcca tgtttccttc agcttcttgt aaagctttct tgcagtccat cattcctgcg
     4261 cctgtacttt ctcttaactc ttttaccatt tgagcagtta tattagccat tttttaagtt
     4321 tcctcctact tattctattc catattataa atggtaaggg cgacccttac catttaattg
     4381 tcaaattatt attcttggtc ttcagctact tcttcctcag caccttgtct accttcaatt
     4441 acagctgttg ccatagcacc agttattaat tttacggctc ttatagcgtc atcatttcct
     4501 ggtatagcaa agtctaattg ttctgggtca cagttagtat caactatacc aactactggt
     4561 atacctaatc tatgagcttc ttgaatagct atgttttctt ttcttgggtc aactacgaac
     4621 attgcacctg gtaattcagg catgtctttt attccaccta agtatttttc tagtttttct
     4681 ttttcagctc ttaattttat aacttctttt ttaggaagaa cattaaatac gccttcttct
     4741 tccatttttt ctaattctct taatttattt attcttgttt ttatagtttt gtggtttgtt
     4801 aacattccac ctaaccatct ttcattaaca aagtacattc cacatctttc agcttcatct
     4861 tttatcgcat cttgagcttg ttttttagtt cctacgaata agattggctt tcctgtttca
     4921 gctacttctt tagtgaactt gtaagcttct tcaacttttt taactgtttt ttgtaagtcg
     4981 attatatata ttccatttct ctctgtgaat atatacttag ccattttagg gttccatctt
     5041 cttgtttggt gaccaaagtg aacacctgct tctaataatt gtttcattga tattactgac
     5101 atatcttacc tcctggtttt atacctccag cttgatcttc tccctaaaaa accatgtaat
     5161 aggcaccttt taaggatccc aatgctgtgt gtgatttatt ttattttttc acctctagta
     5221 gtatatcaca gaggcgaaga aataacaata ttttttccat attttctatt tttatatttt
     5281 tttgtgtatt ttataccatt ttttgaattt aatttgcaaa tttcattttt aattttgttt
     5341 ttaatgatac gttatctata ctattattac ttactatatc tacacttcca agtaagtcac
     5401 ctgaactagt ataatatttt ataacaccca tagtatcacc ttttttaaca gggtactcta
     5461 tatttttaat cttaacttct gattttatac tttcatcatc ttttaatatt gtataaagtt
     5521 catcttttgc ttttaatgta acctctaact ctttcattcc ttttatatat ttcttaccaa
     5581 taaagctatc tttatcaatt acttttttca tattgaaatt ttcttttcca tatttcagta
     5641 gagctaatga agcagaggtt cttttatttt tatggttagt acctaataca acccctatta
     5701 ctctacgttt tttctcattt ttctcatttt tatttacaac catagaaaat gataagcaat
     5761 atccagcatt gccagtatat ccagttttta taccatctac ttctggtata attcttaata
     5821 atgcatttgt attgcttttt tcaaaacttc tatctgaatt tgtatatgtc tccatatcag
     5881 ttatagctgt tacttgtttt tcataatggt caaacatgta ttttccaaga atagctatat
     5941 cttttgcagt agagatattt tcttttgctg gttttttggg gttgcttaaa tcgtatattg
     6001 gaagaccatt tggatttaga aaatgtgtat tactcattcc tatttctttt gcttttttat
     6061 tcattctatc tacaaatgct tctttcgttt tacaaatatg ttttgctata gcaattgccg
     6121 catcatttcc tgatacaatc ataagacctc tcataagctc tataagtggc acttcttcac
     6181 catctttaag tttataactt gaccctttta ctgatgcaat agatttgtct atttttacct
     6241 tatcagtttc ttttacttct ttattttcaa tagcttctat tgcaagtaaa aaagtcatca
     6301 tcttacttaa actagctaat ggtaccttca tatcaggttc tttactatat aaaactctac
     6361 ctgtttcttg gtctataagt atagatgttt ttgaatactt gtctacagat ttaccatctg
     6421 catatgaata atttggtatt ataaaaacta gaatcatggc taatgatata atttttttta
     6481 gtgcattttt caaatttttc accttcttgg attattaagt atatttatat ttaaattttc
     6541 cctatttggt ccaatttata tctagtaatt aatacctatc catatttaca caaatattac
     6601 cttatcattc ttttaataat cacagatgcc caaattgctc ctattgtaac tccaaaaaat
     6661 acttctatac ctgccaatgc tttcccaatc aaacttgtag caaccatatc tccatatcct
     6721 actgtactaa atgtagccat gctaaaatac cataaatcca tatacatttt gaaaatctca
     6781 cttagtgagt aatcacctat attgtttata tctaaagcta caagtgtgct atttgaactt
     6841 tctatgccta caaataagta taataaagca aaaacactta ttattgctat aatcactaat
     6901 aatatattcc atggcttttc tccataacct gttgtgtaac gtgctatttg gtcaaaaaat
     6961 ttttcaacta aataatcact gaaagtagga taattagaac gtttcattat tttactacta
     7021 taaattcttt ccttataata gtaaaatcct atcatctcat attctccaat ttttgttgct
     7081 tgatttctag ctattctata atttatcttg ccatgctcat actcactttt tccatattca
     7141 acattcttta acacaaattt tgtacacatg ctaaaaatta ttccatccat tcgtggaaaa
     7201 ttttctactt tattaactac caaatcaggt cctttaaatt tcactttttc aaatatacgg
     7261 tcatttatat agtttttact aaatatggtt ctattaaaat cacagttttc taagaatata
     7321 caaccattaa ataaaacttt atctctaaat tctgtatagt taaaaataat attcttttta
     7381 aaaatatatt ttttaaaatt tgctttttgt ttaaatatgg attcagaaaa atccagtatt
     7441 ttataattgt aagttaatat ttcttccgca ttaaattcat tttcaaaaac aaatccatta
     7501 aattcactta tctcttcttt atgaatagta tccatcatca actgtatctc ttcatcagac
     7561 ttattttctt tatgaaagat acaatatcca gaagaatctg cttctctatg acattttttt
     7621 ctctcatcta tcttagatat ccatttacaa ttcataaata tatatcctcc agtacaaaac
     7681 aattattact attttgtatt agtttggata ttattttatt ttatatactt aaatagttac
     7741 aaaatatata ttagattctt agttttaaat ttttaatcta cttcattgtg cttttaattt
     7801 gtttcatata aaaaataata aattttatat actttgattt atttatatat taaatattat
     7861 tctaaaactt acttatcatt tttaagtaat tttgtaacta tatttaatgc tactaaatca
     7921 tccataaatc ctattgggaa cacgaagtct ggaatcacat ctgttgatat aacaaagtaa
     7981 agtagcatac ttccaatcaa taaatatttc tttattgtaa gtccatctgt acaaaaatca
     8041 gcatacattt gtcttaatct atctgtaaat tgaccttgtt tttcaataga atctattttt
     8101 ttattaaaat tatcaaaaag taatttttta ccttcatctg tttggacata taacttacac
     8161 ttacttaact ctttttcaat atttccatta aagttcttat cattgattaa atttgcaaat
     8221 ccaagaatat catcaaagtt actaaaatca ctatctgcat taaatatttg attattgctg
     8281 tttctaaatt catatcctga agctttcaac agttcttcta ggttaatatt taaatgtatt
     8341 gccatctttt ctaaatgatt tatatttggc ctttgtttat tattagctat acgagatata
     8401 gtagatttat caattccact ttttttactt agttctccca ttgataattc tttttcatct
     8461 aataaaactt tcaacaaatc accgaaattc ccaaccttac tatgttgttc cattattttc
     8521 acctgcttta ttatgattgg ttttatatta tatgatatga ttcttttgtt atttaggtgt
     8581 tgtatgatgt tgaaatttta tcaacaattt attggattat ctgtaacaat ttatccattt
     8641 ttacaatact ataactaata taagtacaaa atttaagaga aaggatgtta atctactgtg
     8701 attgaatcaa ttttattagt tacttctctt tgtatagatg cctttgtgac aagctttgga
     8761 tatggagtaa ataaagttaa agttccctta tattcaaata taattatcag cgtagtttgt
     8821 tcagctattt tagcaatatc gctttttgca ggtacaatag ttagagattt tttacctcaa
     8881 aatataacaa tgttaatatg tttctttatt ttatttttat taggaagtgc tagactaatt
     8941 gaaagttttt ttaaatctta ttttaagaaa aaatctatac actcaaagaa ttataatttt
     9001 aatatgttag accttgaatt aaattttaat gtaagtatcg aacctgatgt cttagataca
     9061 agtaaatcta aagtgcttaa atctgctgaa gcatttacac ttgcacttgc tttaagttta
     9121 gatggattag ctatcggttt tggtagtggc cttgtaggtg tgaattatat acaagttatt
     9181 ctattttctt taatatcaaa tataattgca gtattacttg gttgtttact aggaaatatg
     9241 tttgttaaaa acgtaaattt aaacttatct tggttaagtg gtttaatctt gttagtcatt
     9301 ggatttatga agatatgtta ataagaaagc aatctaaaga taaacttttc tctttagatt
     9361 gctttctttt gtgcttttta tatttatttt ctattctctc taatttcttt ctgaatcttt
     9421 ttaagagctt tttttgaacc tctttgaata tctttttcta attttctttc tttaaaacta
     9481 gtaaataata catctaaatc atacccttct ggatacaatt ctgatgcttt tatgctaagt
     9541 tgtaatcttt ttatatttac tgaaataaaa ttatcattaa acaatacttc tacattatta
     9601 aacttgtcca taggcttata tacaattcca aaatcatctt catctagtaa ttttacctta
     9661 tcccctacat tataatctgt atagcttaaa atgacttcag aactattttt atcttcaata
     9721 ttagattgta gcttacttct tttaactaaa tctaaattgt agtttctatc aattacatat
     9781 tctttagctc tatctaaaac tctatttttt attcccattt ttttagaaat aaaaagagca
     9841 ttactatctt cagattttcc aatagttaac ttatacaatg gttctaacgt ttctttatca
     9901 aacatcatac cagcattttc aaattctgga tgtaatgtag caaacttttt tatctctcca
     9961 taatgagttg atgctatagt tatacatccc attttgtaaa actcttctaa taatgatatt
    10021 gctaaaccag ctccttcatt aggttcagtt ccacttccta tttcatcaaa cagaacaaga
    10081 gtagaattat ttgataaact cataatctct gcaatatttt ttatatgtga tgaaaaagta
    10141 cttaaggcat tttcaatact ttgattatcc cctatatcta caaaaacttt ttcaaataca
    10201 ctaaattcac taccttcttt tgcagaaata tcaaatccac attgaaccat taaagttagt
    10261 aaaccaacag tcttaagggt tacagttttt cctcctgcat taggacctgt tattataaga
    10321 cttctataat ttttgcctat ttcaaaatct aaaggtactg catctcctgt tagaagtgga
    10381 tgtttacctt taattatttt tatatagcca ttattattta tttttggagt aattcctttt
    10441 attttttgac tatacttagc ttttgcaaat accatatcgt attctgaaag tatctctata
    10501 tttaatttta tctgacttat cttctcaaat ataagttctg ttaaataaga taatattttg
    10561 tattcttcaa tagtttcatc agcttttagc atagttaact ctgtacttaa atttgaaaca
    10621 ctaataggtt caataaatac agtatttcct tttgatgatg tatctaatat agtaccatta
    10681 acttcatttt tataagaaga tttaattggt attacatatc tatcatttct tttacttatt
    10741 ataaactctt gtatatactt tttatttaca gttgatgtta taaatttatt taatctatct
    10801 tttatctttc cttctgtaat ttctatattt cgtcttatct tttttaattc tttactagca
    10861 ttagaatcaa ctttattaga ttttatacag taatttatct catcttctat acttttacat
    10921 tctgttatat ttaaagcata agaacttaat gtaggtgaat aaaattcttt ttctaacata
    10981 aaagctttca tcttcctaca acctcttaaa aaatcttcaa tatttacaag ttcaacaggt
    11041 tctattatca ttcctttttc aattttatct attgtagaac ctgcattaaa caatccttca
    11101 agtggtatgt gattactatt ttcaattatc tttctagctt ctttattttc tgctaatttc
    11161 cttcttacta ctccaatatt cccactagga gttaatttat ctattaaatt ttttcctagc
    11221 gaacttacac aatgtatttt tattaagtct ttaacttcat ttagttgcaa tctttcaaat
    11281 gtattactat tcattatttt ttctccttta tttataagtc atcgtctttt aaatcaccct
    11341 atcatttact ttgataatag ttattttgcg aacaacttaa taaataagga gttattatat
    11401 atcaaactcc ttatttatta agaagtttaa ctccggactc attaatgtta gtattttttt
    11461 tcataaaaca cttctccttt tctattctta tttaaacact tataccagtg cttctaatat
    11521 tattccataa attatatatt tatgtcaata aaaataatgt tattaatgtt tttgtacagt
    11581 gaaaattttt atagtgaaaa taagcttata ctttcattta tattttggaa ttacttatat
    11641 tgtcatcaat tcatgtatgt gtagtttcca atacaatcta actttgtaat cattatatat
    11701 caaagaattt agctctataa attatcgtct ctataaaata aaaaaatagc taataataat
    11761 aaaacacttt taaatgttcc ataaaattag ctatttataa tataatttta atctttttta
    11821 actttaaaaa ttatccttta taagtaatca atggcttcat agttgccact acttgaataa
    11881 gttcatattc tatcaaactt tcaataatct gctctatatt cttatatgcc tctggagctt
    11941 cttgaaataa taaatttaca tcattacata taatctgact tttaaattta gtttgtttta
    12001 tagtatcttt actatactta cttttaaggc gcgatttaca aactgaacga gaccattttc
    12061 tacctgctcc atgtgataga gaatataaag atatctctgt attttcagta ggcataacta
    12121 tatatgatag actgcctctt gaacctggta taatcacagc tcctctttca cttgaaacag
    12181 caccttttct atgtataaat ttatcttccc ttttctctat aaagttatga tttatagaga
    12241 atattgtttc aacatcttca gatgtaccta ttgactgcat aattttttta ctgatagctt
    12301 cacgattacg ctctgcccac attaaagcat tatcatgttt tttaatataa tctattgctt
    12361 tctcactttc aacttcaagt ccatctttat cataaaattt ttttaaaata tcttctccat
    12421 aatttcttga cccacagtga actaacatca taatatcatc agatgaaaat tttaattgtt
    12481 caaattgttc tttattataa atttcactta tacattgaat ttctacaaaa tgatttccac
    12541 tccctatagt tcctaaattt aaaattggac attcttcttt atatgtgttt tttatttcta
    12601 tatcggacaa atctttaatc ttactaagtg acttaatcca tttgtctttt ttaaatttct
    12661 tttttagaac cccagtttta aataaagtca ttccgcatcc tatatcattt ccaattatat
    12721 gtggataaat aatattttta gtctcaactg ctaaacctac aggtatttta cctgtatgta
    12781 agtcaggtaa tcctactact cttaaaattc catttaactt tgaaatatct tctagttgtt
    12841 tccttgctat atcttcaatc caacatttat tacttgctat tatttttata ttgctcataa
    12901 tttgctcctt tttaatattc tcctgccttt aaaaagtagc aaaaagctgt gacctttagc
    12961 cacagctttt ttattctaaa ctgtaaaagc aggtggctat ttgttaaaat actcctagac
    13021 gtttaatacc tcattatttt ttgttaacat aataaccact tcctttcata atttaagact
    13081 acactaaaat ttctatgtat atcatttata gacattgatt ttaaaatact taatatacaa
    13141 tttttatatt atggaactaa taataatcat tgaaatcatg actatagcta gaccggcaac
    13201 aacaagtttt ttatgtaatt tttttctcat tttactttta tattcttttt taacttgtat
    13261 aactttgtct tgtttctgtt cttcttcttt ctcatcttca acttctatat atgctttttc
    13321 atacattact ttacttaaat caataataat atcattggct ctagtatact tattatttct
    13381 tccaagaagc ctttttataa catttataag ttctgtattt ccattaattg cttttatact
    13441 attccaatct aatcccttat caatagattg tagcattttt tcttctgaat ttgattctcc
    13501 aaaaggcaat tttttaaata tagattcaaa tagaataaga cctgttgcaa aaaaatcact
    13561 ttctttatca gtataattta tacatagttg atgtgggcat aaatatctcc tgtttccata
    13621 gcttcttgta ttaaccccat tatttgcttt tgtaattcca aaatcacaaa tttttatatt
    13681 gtattctgta tctactatta tactactcga ttttaaacta ccatgatatg aatgattcct
    13741 atgtatcatt tctaaagctt ttaaaacttg tatcattatg tttacaattg cttctaaatg
    13801 aagataatta cctagaatta attcatctag tccgatacca ttaaagtctt cacttacaac
    13861 ataatataat gttgtttctt ctgtacagtg aatcccaaca tctattattt ttagtatata
    13921 aggagagttt atctcatcta aagcagtact ttcatcaatt aaatttgaaa caaaatcttc
    13981 acaaatataa ttattgtgct ttataacttt tattaacaca tttctcctgt aaaaaacatc
    14041 tctagcttta tagattttgt taatttctaa aacgtcatca gaatttacta cctcatatct
    14101 attgcctata aaattcaacc atgtcacctc ctcatacatt ttatataact aaatctattt
    14161 acaattatac caatatatag gaatattttc tatatattaa tgattgtaat attaaaacaa
    14221 gaactaatag tgttaatttt tacaaaaaag gctgtctcaa aatagagata cgcttctttt
    14281 gtattgttga aatgatgaaa atatatttga tttcacataa aaagagtgtc tcataaacta
    14341 aaaagttcat tttgagacac tcccttttat attacaaata tttctctaaa aaattatcta
    14401 tttttttaat tctttataag aactatttga tatatgttct ttttttatga cctttccact
    14461 tgaatcttta aatattcgat atgtagaata tttattctga ccagtttgtt ttacctctat
    14521 agatatattt ggtttgtcac cagaattacc atagattact gatgatacac ttcctccacc
    14581 tgcataattt ttaatatata caggatgctt atatggattt ttaaacttta agtttaatcc
    14641 tccatcgctc acagtagcat ctcttccttt aggcacataa gtagatgcag atgaatgatt
    14701 tgtaacttga gttatctcca tacccgaaag aagagccgca ttataaactg ttgaagatgt
    14761 ttgacaaaca cctcctcctg ctgattgttc tagcttacca taaactataa caggtgcatc
    14821 tttgtaacca tttgctttat tactaggtcc tgtaagttta ttgtatgaaa attcttcacc
    14881 tggcattaat aatacatcac tagtttttct tgctgataat cctacattat atgacctacc
    14941 ctctacagct tgtgaataag tagttgaata ttgacctata acagaattta cagtttttac
    15001 ttgttcagtt gttatatctg gtttttgaag atttacttta agttctaaag ttttatgctc
    15061 tttatttttt atcatattat atatagactc tttatttgct gccaaatcaa attctctacc
    15121 tacaacagag tctgtataac ttagtccacc acttccaaca ctaatagaag catttttcat
    15181 cttaacattt atactatctg ctattgaaga cactttggaa ctaagttttg cctcatcata
    15241 ttcagctttt atcttcatat ttgccttatt cactcttata tcaatatatt tttttaagtt
    15301 ttgaaaatag gacccttttt ttgtactttc ataagcatct tttacaacat cttctgtatc
    15361 atattttaaa tcaatatctt ttggtgatat tgtatatttt ttcccatcat aagtaagatt
    15421 taagtcttct ggagtatact tatctgttat agcttttaat gcctctgctt tagtcatatc
    15481 agatacattt actccttcta tatatacatt tttagcgatt ttcccattgt acagaaattt
    15541 actgttaaaa aaataagtaa atccacccat tattagaact aaagctgcca atacaattaa
    15601 aacacttcgt tttttttctt tacctaatct tgaaactctt gttgttcttc tgcccataac
    15661 ttcacctcat tttgacacta gcttaaattt gcataataga gttcccattt caaaactacc
    15721 ttagattata tttgaatagc ttttgttaaa caaggaattt aatcaaatgt aactttattg
    15781 taaatttatg tcttataatt agttttattt ttgatatttt ttattatatt tcttttacta
    15841 tttcttaaca aaaaattgtt tattttataa caactaattt catttatatt gaaatttaaa
    15901 tgtaacctat tacaggataa tggtctgaca ggtaaatttt ttctactgtg tatcctttta
    15961 attcagtatt tttattaaca aaaatgtaat ctattctaga gtttgatttt tcaaatgttg
    16021 gtaagtaaga cttgtttagt gaaatagcca tatcattaaa catacttaaa aagacatttt
    16081 tctcattaaa atcaccacat aaaataacta tccccactaa tctgttccta tagtctatta
    16141 tttcgtctaa ttgttttgct ctctcctgcc tatcaagtcc caagtgagta tttattacat
    16201 ttataattct tccatatgca tctatagtta tacaaagagc tccccgttgt tcttttttgc
    16261 tagttaagaa aaaatgatta ctgtttaaca ttttagatgt tgtaaatgta caaataccat
    16321 atatcatatt tacttttttt acatttgtag caaagacacc atccatattt aaaacagctt
    16381 ttaaagctaa aaattgagga tataatactt cttgcaaaca aattacatca caatccaatt
    16441 gttttaaata taaccccatt ttagttagag ttaatctatt atttgaatcc atacctttat
    16501 gaatattgta ggttactatt ttcataataa tatcacctct tatgcaatat aatacttact
    16561 aaaatttaaa cttatttact tttcacttaa gaccattatt tatcttataa aattgagtac
    16621 ttataaactt tatcacaaaa aaacctaact taagtattta tattctacat aagttaggtt
    16681 ttataaacta ttataatatt tattatttca ttcatttcta atgatgattc tcctttttta
    16741 tctttttcaa tttgccttca ctaacaacaa ataaaaatcc catcttcttg tatatttcat
    16801 ccaattcaat taaagttact tcaccatttt ttaaatttgt taatgttata tcttgtattc
    16861 ttcttgatgg aattatcata agttatcaac actcctttaa attcttttta atctttatat
    16921 ttaaatatat ttatgcattc tgatatatat tcataaatta ttaaaataaa ttcaaaaaac
    16981 acccgttctg caaacattcg ttctgtatat ttattataca tcatacagac gttcgattca
    17041 atataaaaat taaatatatc tcgtttttag taaattttac aatattatac actaaatatg
    17101 tcaaaacatc ttcttgaaat agattatctt gtcaaacaaa aaaaaccatt tcagtaaaag
    17161 cttctgctta aattgaaatg acttttctta tttaaattat taattttata ccatattttt
    17221 attaagctaa catatgtaat atttgagtta ccacaagagc acaataagtc cctataatat
    17281 ttcctagaag ccccataagt acacctactg gtattaatac aggattgtga accccagcaa
    17341 tcattggagc tgtagttact cctcctatat tagctatact tcctacttca caagtaaata
    17401 aatcaagttt aaatagttta gcaagcccta taaatgaaat agcatgtaca aggactacta
    17461 ccaatccaaa cattatgtaa acaggtgctt ctgacaatcc aaagaaattt gctttactac
    17521 ctgtagctgc aaggagtaaa tacataaaca catttcctac cagtgtactc cctttaagct
    17581 ttgatatttt tgtcataccc aataatattg atactgtaga tgcaacaagt actacccaca
    17641 tagtttcatt aagtatacct gaagttggaa gtatcttgga tacaatttgt gcaaaagacg
    17701 caactccaaa cccaacagaa agtaaaatca taagttctac aaacgtaggt gccgtattat
    17761 ctttattttc tttttcaagt tttgatgtaa cctcatctat aaaacttgta tcgcactttg
    17821 tccatttgtt aaatttaggt ccaaatttca cagacattag acaaacagac atccatactg
    17881 tatatcctat agaacccata agtattgcat aactaagtcc ttcttctgca actcctagag
    17941 cattagctgc tgcaatcata tttgatgagc cacctatcca tgaaccagat gctgccccaa
    18001 gaattttcca tgaatctgca cccattgaat ttttaaaaat tatgaatgct ataacaaatc
    18061 caagcataaa tgtaaatgta gcacagaaaa atgataataa cattttaggc cccatcttta
    18121 atatttttct taaatcacat tgaattaaca agaacactaa cattaatgga aggaagttca
    18181 ctgttattat gttttgatac gttccaacat cttcattctg tgcaaataaa ccaaatgatc
    18241 caagtatagc tgaacctaag tatattaaaa gcattggatt aataacatca aataccttcc
    18301 atttcaattt atcaaccata aaaaaaatta cacctacgaa tacaaccaag aaactacaat
    18361 atacaaatcc agtctcaatc acattataca caccctttct tttcctaatt aatttgattt
    18421 ttatgatttc taagtaaaga ctttttcaga taatagacaa ttaaaataaa tacttttatc
    18481 tatatcatgc taattaaata catatatacc taactattga catatattaa taaagatttg
    18541 cacattaatt actttagaaa tgaataatct gaatttaa
//
LOCUS       DAMJWO010000084        18237 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.086, whole genome shotgun sequence.
ACCESSION   DAMJWO010000084 DAMJWO010000000
VERSION     DAMJWO010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18237
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.086"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(247..1344)
                     /locus_tag="PC366_003000"
     CDS             complement(247..1344)
                     /locus_tag="PC366_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HDF2578497.1"
                     /translation="MKKTYLFSPGPVMVTDKVRNSLLHYDICHRGNEFMDLFKDTQQK
                     INKLYNATSNYYSLIVSGSGTSVNECVLSSIFDKEDAVLLVSNGVFGERLEEILFTYN
                     VKTYKPNFEWAEYPDLDILEKYIIENSDIKVIAMVFHETSSGMINPVPELGKLAKKYN
                     KIFFVDAISASAGEYIDVEEFNIDIITGVGGKALGAFPGSAYLCAKESILQNIKENQC
                     KNVYLNLYKHYKVAKSSSQTPNTPNVTLIFALNEALTEFLEDDSKIERYKECSAILRN
                     GMEELGLTFLLPDKYMSNTVTSVFLPKEINVNEFILGLERESGYVVYPGKGKFLDANI
                     FQVANMGEIYPEDCYKFLDILKSKLEIKKVI"
     gene            1637..3163
                     /gene="glpK"
                     /locus_tag="PC366_003001"
     CDS             1637..3163
                     /gene="glpK"
                     /locus_tag="PC366_003001"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDF2578498.1"
                     /translation="MKYVLAIDQGTTGTRAVLINEKSEFVFSDYMEHTQIYPQSGYVE
                     HDPIEIWNNTKTVSNNVLQQAFESGINESDIKGIGIDNQGETVMLWDKNTGKPLYNAI
                     VWQCRRTYDYVENLKNIPGLENKIIDKTGLIIDPYFSGTKIKWVIDNVKGVKEKIKNG
                     EVLAGTLDSWLIWKMTGGKSFLTDVSTAARTMLFNIRDMDWDRELLDIIGVPRSILAD
                     IMPTSGDFGTTDKEAFCGVSIKITASMVDQPAALFGNGCFEPGMVKNTYGTGCFLYMN
                     IGEELNIAGNGILTTVAWKIGDKVTYAYDGGVYIAGAAIQWLRDGIGVIKNYSETDDM
                     ANSISSTGGVYFVPAFAGIAAPYWDQYARGTMVGITGSTKKEHIVRATLESVALQVKD
                     VVDSMNLASGKEIKMLRVDGGITKNNFTMQFQSDILDIPIEIAENPETTVLGVGYMAG
                     LSCGVWNSIDEIRSEFTISKKYIPNMTKQKREEILLGWNQAVKRAMNWENDTKKVCAN
                     "
     gene            3204..4319
                     /locus_tag="PC366_003002"
     CDS             3204..4319
                     /locus_tag="PC366_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HDF2578499.1"
                     /translation="MPFDKIILYIMAVGVLLGALDRIIGNKFGLGEQFEEGFNSMGPL
                     ALGMVGIVCLAPVISDVLGPIIIPIFNLCGADPSMFATILANDMGGYPLAMELAHNKE
                     AGMLAGLVVSSMLGCTLVFSIPVGLGLIEYEDRPFFAKGLLIGLITIPFGGIIGGLIA
                     GFNLSMVIINMIPVIILAVILAVGLKFNSTLMINGSLVFGKFISILITIGLGAAAFQE
                     ITGIVLIKGMTPIREGIQVIGSIAIVLLGTFPILHLLVKVLNKPLTIVGGKLGMDATS
                     AAGLVFTLANSIPVYKMMKDMSPKGKVVNTAWLVCATAALGDHLGFTAGVVPEMITPV
                     VIGKLVGGVLAIALAILMTKDLTLEEEQSIKMKKDAV"
     gene            complement(4600..5364)
                     /locus_tag="PC366_003003"
     CDS             complement(4600..5364)
                     /locus_tag="PC366_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDF2578500.1"
                     /translation="MLPQERYEKILSILKSDNIIKINDIVQMFDISIETARRDLAHME
                     SIGLLKRVYGGAIPVIASSVELNYVKRKKINSNDKKQIAIKCSEFINTNDTIFMDTGT
                     TVLEVSKNLKDKKNLTVITNSILVANELMNTNIKVYVLGGYLRETEGSFSGPLTLSAI
                     EQFNVDKAILGAGGITLENGISDYHLEEALVRKKMIERSRKSIVVVEPPKFGINSFAS
                     VAPIEHIDTIITSASIDHNIIIEFSQKGIPLVIADN"
     gene            5623..5713
                     /locus_tag="PC366_003004"
     tRNA            5623..5713
                     /locus_tag="PC366_003004"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5657..5659,aa:Ser,seq:gct)
     gene            5801..6589
                     /locus_tag="PC366_003005"
     CDS             5801..6589
                     /locus_tag="PC366_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HDF2578501.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHIGVLFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLAFKNKKPNNIENIIYFKEIATKARKEGLLSVDKEISEND
                     ELDPFIRKGLELMVDGVDAVTIRNILESQIQITSKRHKEGIAIFDSAGGYAPTLGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEISE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            6610..7350
                     /locus_tag="PC366_003006"
     CDS             6610..7350
                     /locus_tag="PC366_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDF2578502.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEPGSNDLDSLQNAKFKKVGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAVVKDNSRDKIIQIGKMLNEMNSYMRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSKDK"
     gene            7528..7902
                     /locus_tag="PC366_003007"
     CDS             7528..7902
                     /locus_tag="PC366_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578503.1"
                     /translation="MGNKNKNTKYKDKTRERYNKKVENLNKEKLNKDNKQSKKVDKID
                     DIINKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVK
                     ALFSIFVIVCFLIAFKYVVNPV"
     gene            7994..9454
                     /locus_tag="PC366_003008"
     CDS             7994..9454
                     /locus_tag="PC366_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDF2578504.1"
                     /translation="MNRCKFAKLIITSMIVLLLTGCSLKKEDNYKLDPENPTSIQIWH
                     YYNGQQKMAFDKLVKEFNDTIGAEKGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELNEYIDEYVEEGRINSKDEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIEEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFKGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLNVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDSNKINELV
                     KSGTSKKDAVAQFNNDKNFETWFESFKAELENAIKK"
     gene            9507..12383
                     /locus_tag="PC366_003009"
     CDS             9507..12383
                     /locus_tag="PC366_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2578505.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEATINSSVKKILNEKNALIEDVGNNE
                     EINKDIIKSISNDLIYLLRKNSVTGAFIILNDKNINDKPIDSKGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQEGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRLMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNNDMAFENVISNGYSLKEKFWDGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLDLYNSNTPFENERWALLGIIEEKSLLSFSKRIEKLVIISI
                     AISLLIGLIGIYIASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNAENVFCTKDKKLKWIRMNIFEDELKVLG
                     VVVDVTKEFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKIAAFIMWDLD
                     NLKYINDTYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRD
                     IINSVKKQMNNTLLKLHDGTEFKIRASAGISWYPDDSTNYDELMRYADFAMYQIKNTI
                     KGEVSEFDINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPK
                     IKTFSSPIDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLS
                     KVDFEEIEDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNG
                     DAVLLYIMPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVISEGVETKGEME
                     TLINLGVDYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            12460..14526
                     /locus_tag="PC366_003010"
     CDS             12460..14526
                     /locus_tag="PC366_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDF2578506.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLNNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLICSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVYTANRLIDKNKNRYEKVIKCSQGDGGSVTYISPHDSEEEAL
                     YIAKEIIDEIQKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDEKDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     misc_binding    15118..15328
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15554..16369
                     /locus_tag="PC366_003011"
     CDS             15554..16369
                     /locus_tag="PC366_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF2578507.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDNGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKDVTEGMAAAIKKSDNNKDFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     gene            16397..17074
                     /locus_tag="PC366_003012"
     CDS             16397..17074
                     /locus_tag="PC366_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF2578508.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            17133..17855
                     /locus_tag="PC366_003013"
     CDS             17133..17855
                     /locus_tag="PC366_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004398740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDF2578509.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEILLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
BASE COUNT         7180 a         1929 c         3243 g         5885 t
ORIGIN      
        1 tgaataaaaa acgattgcgt caaaaataaa aaacaattaa atgtaagaat aattatgtca
       61 aaaatataaa ataaattaaa agaaaaagat tatactgaag gaaaaagatt tgaaataggg
      121 gtgaacttta catattatag ttcaccctta tacaaaaata taaaatataa tttattatag
      181 gaaaatttaa aaaaatcagt ctatttaatt tatactgatg tattgtagga ttttacaaac
      241 aaactgttat ataacttttt ttatctccaa ttttgatttt aagatatcta agaatttata
      301 acaatcttct ggatatattt ctcccatatt tgcaacttgg aatatgttag catctaggaa
      361 tttgcctttt cctggataga caacatagcc actttccctt tctaggccta atataaactc
      421 atttacattg atttctttag gtagaaatac agatgttact gtattagaca tatacttatc
      481 tggaagtaaa aatgttagcc ccaattcttc catgccattc cttaaaatag cagaacattc
      541 tttgtatctt tctattttac tgtcatcttc caaaaactca gttaaagctt cattaagggc
      601 aaatattaaa gtaacattag gtgtatttgg tgtttgagaa gatgatttag caactttata
      661 gtgtttataa agattaagat atacattctt acattgattt tctttaatat tttgtaaaat
      721 actctcttta gcacaaaggt atgcagaacc tggaaatgct ccaagagctt taccaccaac
      781 acctgttatt atatctatat taaactcttc tacatcaata tattcacctg ctgaggcact
      841 tattgcatct acaaaaaata ttttgttata cttcttagca agttttccta gttcagggac
      901 tggatttatc attcctgaac tagtttcatg gaacaccata gcaattactt ttatatcaga
      961 attttcaatt atatattttt ctaaaatgtc caggtctggg tattctgccc attcaaaatt
     1021 aggcttatat gtttttacat tataagtaaa taatatttct tctagccttt ctccaaaaac
     1081 accattacta actagcagaa ctgcatcttc tttgtcaaag atagaagata gtacacattc
     1141 atttacagat gttccagagc cagatacaat taatgagtag taattagaag ttgcattata
     1201 tagtttattg attttttgtt gtgtatcttt gaataaatcc ataaactcgt ttcctctatg
     1261 gcatatatca tagtgaagaa gtgaatttct gactttatct gtaaccatta ctggtccagg
     1321 actgaataga tatgtttttt tcattgtaaa gcctccttaa aaagttaaat ttaaattttc
     1381 gaatgactga ctatgtgtaa atattaaaat attgtgtgtt attttaacta gattatagaa
     1441 taaaataatg aatattgcaa taatatttca ataaaaatac ttttttaatc accataatta
     1501 aaaataacaa aaaatattgt aatgaatatt gcataaatcc acatgatgat ataaaatata
     1561 aataacttga atagattata tattcaaaaa ataaaaaaga atttattaat tctgaaaata
     1621 aagggggaca ttttaagtga aatatgtatt agcaattgac caaggaacaa caggaacaag
     1681 agcagtattg ataaacgaaa aatcagagtt tgtttttagc gattatatgg aacatactca
     1741 aatatatcca caatctggat atgttgaaca tgaccctata gaaatttgga ataatacaaa
     1801 aactgtgagt aataatgtat tacaacaggc ttttgaaagt ggaatcaatg aaagtgatat
     1861 aaaaggaatt ggtatagata atcaaggtga aacagtaatg ttatgggata aaaatacagg
     1921 taaaccactt tacaatgcta tcgtatggca gtgtaggaga acttatgatt atgtggaaaa
     1981 tttaaagaat ataccaggtt tagaaaataa gataatagat aagactgggt taattataga
     2041 cccatatttc tcaggtacaa aaattaaatg ggtaatagat aatgtaaaag gtgtaaaaga
     2101 aaaaattaaa aatggagaag tacttgcagg aacattggat agttggttaa tatggaaaat
     2161 gacaggagga aaatcttttt taactgatgt atctacagca gcaagaacaa tgctttttaa
     2221 tataagagat atggattggg atagagagtt gcttgacatt ataggagtgc ctagaagtat
     2281 tttagcagat ataatgccta ctagtggtga ttttggaact acagataagg aggcattttg
     2341 tggggtttct ataaaaatta ctgcttcaat ggtagaccaa ccagcagctt tatttggcaa
     2401 tggatgtttt gaaccaggaa tggttaaaaa tacttatggt acaggatgtt tcttatatat
     2461 gaatataggt gaggagttaa atatagcagg taatggtatt ttgacaacag ttgcttggaa
     2521 gataggagat aaagttacat atgcttatga tggtggagtg tatatagcag gtgctgcaat
     2581 acaatggctt agagatggaa ttggagttat aaaaaattat tcagaaactg atgacatggc
     2641 aaattccata tcaagtactg gaggggtata ttttgtacca gcatttgcag gtatagcagc
     2701 accttattgg gaccaatatg ctagaggcac aatggttggg ataacaggaa gtactaaaaa
     2761 agaacatata gtaagggcta ctcttgagtc tgttgcactt caagtcaagg atgttgttga
     2821 ttccatgaat ttggcttcag ggaaagaaat aaaaatgttg agagtagatg gtggaattac
     2881 taaaaataac tttacaatgc aatttcaatc tgacatatta gatataccaa ttgaaattgc
     2941 agaaaatcct gaaacgacag tacttggtgt agggtatatg gcagggcttt cctgtggtgt
     3001 ttggaacagt attgatgaaa ttagaagtga atttacaata agcaaaaaat atattccaaa
     3061 tatgactaag caaaaaagag aagaaatatt acttggatgg aatcaagcag taaaaagagc
     3121 tatgaattgg gaaaacgata ccaaaaaggt gtgtgctaat taagttacaa tagagtattt
     3181 tacatgtata ggaggaatta aaaatgccct ttgataaaat tatattatac ataatggctg
     3241 tgggagtgct tttaggagcg ttagatagaa taattggaaa taaatttgga cttggagagc
     3301 agtttgaaga agggtttaat tcaatgggtc cattggcttt aggaatggtt ggtatagttt
     3361 gtttagctcc agtaatttca gatgtactag gtcctataat aataccaata ttcaatctct
     3421 gtggagctga cccatctatg tttgcaacta ttttagcgaa tgatatggga gggtatccat
     3481 tggctatgga acttgcacac aataaagagg caggaatgct tgcaggatta gtcgtgtcat
     3541 ccatgcttgg atgtacatta gtattttcaa ttccagtagg actaggtctt atagaatatg
     3601 aagacagacc attctttgca aaagggttac tgataggctt gataacaata ccttttggag
     3661 gtattatagg aggattaata gcaggattta acttatcaat ggtaattata aatatgatac
     3721 cagtgataat attggcagta atattggcag taggtttaaa atttaattct acacttatga
     3781 taaatgggtc attagttttt ggaaaattta tatctatatt gataacgata ggtttgggag
     3841 cagcagcatt tcaagaaata acaggtatag tacttataaa aggcatgaca cctataagag
     3901 aaggtattca agtaattgga agtattgcaa tagtgttatt aggtactttt ccaatattac
     3961 atttattagt taaagttctt aataaaccac ttacaatagt gggtggaaaa ttaggtatgg
     4021 atgccactag tgcagcagga ttagttttta ctttagccaa tagtattcca gtatataaaa
     4081 tgatgaaaga tatgagtcca aaggggaaag tagtaaatac tgcttggctg gtttgtgcta
     4141 cagcagcttt gggggaccat ttaggattta cagcaggagt agttccagag atgattacac
     4201 ctgttgtaat tggaaaattg gttggaggag tattggcaat tgcacttgct atacttatga
     4261 caaaagattt aactttggaa gaagaacaaa gtattaaaat gaagaaagat gcagtgtaga
     4321 ataaacaata cttaagtcaa atttaagtta ttttaaagta ggagtttaaa taactaaaaa
     4381 taaattaaaa agacagacaa ttaaaaaata atcgaataac caaaactgat aaattaaata
     4441 aaatggcaat caaataacta aaaatgataa gctaactgaa agtagttaca taattaaaat
     4501 ataaagtata gtttagacat aagtggagct aaataaataa ttatttggct ccttaatttt
     4561 aatttattac atcaaggaac taaaaatcaa tcatacaagc taattatcag ctatgactaa
     4621 aggtattcct ttttgagaaa actctattat tatattatgg tctatactag cagaggtaat
     4681 aatagtatct atgtgttcta taggagctac tgatgcaaat gaatttatac caaacttagg
     4741 aggttcgaca actactatag attttctaga cctttcaatc attttttttc taaccagtgc
     4801 ttcttctaag tgatagtcag agattccatt ttcaagagtg atacctccag cacctaaaat
     4861 agctttatca acattaaatt gttcaatagc tgagagtgta agtggaccag aaaaagaacc
     4921 ttcagtttct ctaagatagc caccaagcac atatactttt atattagtat tcataagttc
     4981 atttgcaact aaaattgagt tggttattac agttagattc tttttatctt tcaaattttt
     5041 tgaaacttca agtacagtag ttccagtatc cataaaaata gtatcatttg tatttataaa
     5101 ctcactacat ttaatagcaa tctgtttttt atcgtttgag tttatttttt ttcttttaac
     5161 atagttaagt tctacgctac ttgctataac tggtatagca ccaccataaa ctctttttaa
     5221 aagaccgata ctttccatat gggctaaatc tcttcgtgca gtttctattg atatatcaaa
     5281 catttgaact atgtcattta ttttaattat attatctgat ttgagaatac ttaaaatctt
     5341 ctcgtatctt tcctgtggta acataaaata tcctccttgg actagtatta ttttagtttt
     5401 ggcataactt acaattaagt cagagtttag gtatatttgt taatgtatgt atatttatca
     5461 aataatatta taagtgttat gcaagataat tttaccatat ttaaaactta catttaagca
     5521 aaaaagtaaa aatagatgtt taataattca aaataactca aattttataa aacaattgac
     5581 taaaatatga ttttattata taatttacta gtatagagat atggagaagt actcaagtgg
     5641 ctcaagagga tcccctgcta agggattagg ctgggtaacc ggtgcgaggg ttcgaatccc
     5701 tccttctccg ccaattgtta aaggctattt ttattaaaga tagtcttttt ataatgtcat
     5761 aaatgattag atatgtataa ttaaagaaag gagggaatag atgacaactt taattttttt
     5821 catagtgggg atagcatctt tggtagttgc ttttgttatt gatgggggac atattggagt
     5881 attatttgta ttttcatcag cacttgttgt gtttggtgga actataggcg ctgttggagc
     5941 ttcgactcca ttccctgtgt ttaaaaagtc tataaagata atgttattag cttttaaaaa
     6001 taaaaagcct aataacatag aaaatataat ctatttcaaa gaaattgcaa caaaggctag
     6061 gaaagagggg cttcttagtg ttgacaaaga aataagtgag aatgatgaat tagacccttt
     6121 tattagaaaa gggcttgaac ttatggtaga tggggtggat gcagttacta taagaaatat
     6181 attggaatca cagatacaga taacatcaaa acgacataaa gaaggaatag caatttttga
     6241 ttcagcaggt ggatatgcac ctacactggg gataataggt acagttatgg gattagtaca
     6301 tattttaggt aatctttcaa gtaatccaga tgcattagga cctcaaattt ctgttgcatt
     6361 tttggctact ttgtatggtg ttggttctgc caatttaata tggttaccaa tagcatcaaa
     6421 acttaaggct ataaatcaac aggaaataag tgaaagactt ttggtgatag aagcaatatt
     6481 atccatactt gagggtgata attctaattt aatgacagaa aaattaaaaa tatttttaaa
     6541 ttcaaaagaa ctaattgaac ttgaagaaat tggtggtaga gctgaataat ataaaaggat
     6601 ggaatgttta tgttgtatga tgaagatgaa aaagaagaaa acaatgagcg atggctttta
     6661 acttattcag acctcataac attacttatg attttctttg taataatgta ttctatgagt
     6721 aatgttgatg cggagaaata taaacaatta tctcaatctc taaattctgc ttttggtggt
     6781 tcttctggag ttattgaagg tggtaatagc aaaatagaac cagtagttga accaggaagt
     6841 aatgatttag atagtttaca aaatgctaag tttaaaaaag ttggtgaaga aatccagaag
     6901 tatttaaatg aaaatggtat ggctaattca gtatcattaa gagttcaaga tagaggatta
     6961 gtaataagcc ttaaagatac aatactattt gatacaggaa aagcagttgt aaaggataat
     7021 tctagagata agattattca aataggtaag atgttaaatg aaatgaatag ttacatgaga
     7081 gtagaaggtc atacagacaa tatgtctata aaaaattcag agtttaagtc aaattgggat
     7141 ttatcagtta tgagagcaac caatgttgtt caacttctta ttgacaatgc aggtatagca
     7201 ccagataaat tatctgctgt aggatatggt gagtttagac caatagcaga aaattcatct
     7261 gaagaaggta ggtcaaaaaa tagaagagtt gatatagttt tagttgatag taaatatgat
     7321 aatgtagaaa atgtttcaaa ggataaatag ttaaattagc tgtctcaata cagaattaat
     7381 tctaaaggag atggcttttt tatgcgaaaa ttaaaaatag atacatagta agttaccttt
     7441 ttgtaggaat atatggtatc ttaaatatat aatatttaaa taatatataa gctcaattaa
     7501 aaaaatttta tagaggatgg gaaataaatg gggaataaaa ataaaaatac gaaatataaa
     7561 gataaaacaa gagaaagata taataaaaaa gttgagaatt taaataaaga aaaattaaat
     7621 aaagataata aacagtctaa gaaggtagat aagattgatg atattattaa taaatctagt
     7681 attgtattat gtgtacttct agtggtgttt tcattacttt acttatttaa attggttcaa
     7741 cttaatataa taatgatact tttagtaatt acagtagcta ttcaacaagg attggtgtca
     7801 tttggtgcat ttagaaataa aaattatgta aaagctttat tttctatatt tgtaatagta
     7861 tgtttcttaa ttgcttttaa atatgttgta aatcctgttt aaatatatca ataaacgttc
     7921 tataattaat ataaatagtg aagttacagt tttaatgcta ttataaattt tataatttga
     7981 aggagtagat tttatgaata ggtgtaagtt tgcaaaatta attatcacat caatgattgt
     8041 tttattactt acaggatgta gtttaaaaaa ggaagataat tataagttag acccagaaaa
     8101 tccgacatca atacaaattt ggcattatta taatggacag caaaaaatgg cttttgataa
     8161 gcttgttaag gaatttaatg acactatagg tgctgaaaaa ggaattattg ttgaagcgtt
     8221 tagtcaaggt aatgtagttg atttatcaga gaaagtttta gattctgcaa ataaaaaagt
     8281 tggctctgaa gatgtgccaa atatatttgc agcatactca gatactgcat atgaaatgga
     8341 taaattaggg ttactagtag atatggataa gtacataagt aaagaagaat taaatgaata
     8401 catagacgaa tatgtagaag aaggcagaat aaattctaag gatgagttta aacttttccc
     8461 aattgcaaaa tcaactgaaa ttttgatgtt aaataaaact gattgggata aatttgcaaa
     8521 agctacaaat tcaaatataa atgatataaa aacaattgaa ggattagtag agacatcaaa
     8581 aaaatattat gaatggacag atagtttaac gaaagagcct aatgatggta aagcattttt
     8641 tgggagagat gctttagcaa attatattat tataggaagt aaacaactag gagtagaaat
     8701 tttttctgtt aaagatggta aagttacact aaatattgaa gaaaaagtta tgaaaaagct
     8761 atgggataat ttctatgtac catatataaa tggatatttt gcttcttatg gtaagtttcg
     8821 ttctgatgat gcaaaaacag gtgatatatt agctcttgta ggctctagtt caggagcagc
     8881 atactttcca gatagagtaa tgctaaatga taatgagagt tataatattg aaacatctgt
     8941 ttttcaagca ccacgtttta aaggagaagg aaaatatgct gtacaacaag gtgcaggaat
     9001 ggctgtaaca aaatctacta aagaagaaga atatgcatca gtagaatttt taaaatggtt
     9061 tacagataaa gagcctaata taaaattctc tattgcttct ggatatttac cagtaaagaa
     9121 aaaaacgaat gatttgaatg ttataaaaga agttatgaag aaagataatt tgagtttatc
     9181 tgataaagtt gaaggttcaa tagcctcatc tattgaacaa attaacagtt gtaatttata
     9241 cactaataaa gcatttgatg gtggaactaa agctagacaa atacttgaat attcaatgct
     9301 tgataaagct aaagaagatt caaataaaat aaatgaattg gtaaaaagtg gaacttctaa
     9361 gaaggatgcg gtagcacaat ttaataatga taagaatttt gaaacttggt ttgaaagttt
     9421 taaggctgag cttgaaaatg ctataaaaaa atagatgaat tggcagttag tgtgtagaca
     9481 agcacaaagg tataggtgga ataagtatgg aaaacaatct aagaaaaaac aattcaataa
     9541 tgaaaaagat gatatttccc ctaattattg ttatgctaat tcaaacaagt ttattttgtg
     9601 ccacaatttt atggggagga actattaaga aattaaatga taattcgttt gacatcttaa
     9661 atgaaagagt aattaatcgt aaaaattata tacaaaatga aatgttacaa agatggtcaa
     9721 atacaagtga aacggaagct acaattaatt cctctgtaaa aaaaatatta aatgaaaaaa
     9781 atgccttaat tgaggatgta ggcaacaatg aagaaattaa caaagatatt ataaaaagca
     9841 tatcaaatga tttaatatat cttttgagaa aaaactctgt tacaggagct tttataattc
     9901 taaatgacaa aaatattaac gataagccaa tagatagtaa aggtgaaata agtaggactg
     9961 gattgtatat aagggattta gaccctaagt ttaatccaaa tgataattct gatttgttaa
    10021 ttgagagagg ttcatcagat atagcaagaa gttttggaat atctatggac agttattggg
    10081 aacctaaatt ttcatttaaa agtgaaaatg agcaagaggg agatgatttt ttttataaac
    10141 catttagagc tgcaattgat aatccaaacg tatcaagttc taatttggga tactggggaa
    10201 gtaagttttt attgacaaat gcaggtgata ggcttatgac atatacagtt ccccttattt
    10261 atgaagatgg aactgtatat ggagtacttg gaatagattt aagtgtaaat tatttaagag
    10321 aattacttcc atactcagag ataaatggaa ataaaaaagg taattatatt ttaggtgtag
    10381 atagaaataa tgatatggcc tttgaaaatg taatttcaaa tggatactca ttaaaagaaa
    10441 aattttggga tggtttacat tctaatttag agcagaagga atcgtataaa aatatatata
    10501 agattaaaaa taaagataat gaatgtggta atggcaacat ttatgctagt gtacaatact
    10561 tagatttata taactccaat actccatttg aaaatgaacg ttgggctctt ttgggtatta
    10621 ttgaagaaaa aagtcttttg tcattttcaa aaaggataga gaaattagtt ataatatcta
    10681 tagcaatttc tttattaata ggtctaatag gtatttacat tgcatcaaga ttatttacaa
    10741 aaccaattgt tcttttagcc aacaaagtta gaaacagtaa tccatcaaaa ccagtaaatc
    10801 ttgataagat aaatatatct gaaatagatg aattatcttc agctatagag ttactcagtg
    10861 caaatgttgc agattcttca tcaaaattat cacagattat tgaaatggta gatatgccaa
    10921 tcggggcttt tgagttatac aaaaacgcag agaatgtttt ttgtacaaaa gataaaaaac
    10981 ttaagtggat aagaatgaat atctttgaag atgagctaaa ggttcttggt gttgttgttg
    11041 atgtcacaaa agaatttatt gagaaaagga agatagaata tgaaagagat tttgatattt
    11101 taacgaatct tttaaatagg agagcttttc attcacagat acaagaaaaa tttaagaata
    11161 aagatgaact taagatagca gcatttatta tgtgggattt agataatcta aaatatatta
    11221 atgatacata tggacatgat gctggtgatg aatatattag gtgtgctgca gacatactta
    11281 agaagtttat atcatggaat ggtatagtat ctagactttc aggtgatgag ttttatgtat
    11341 ttatatatgg atatgaaagt aaagatagta taagagatat tattaattct gttaagaaac
    11401 agatgaataa taccttatta aaacttcatg atggaacaga atttaaaata agggcatcag
    11461 caggaatttc ctggtaccct gatgattcaa ccaactatga tgaattaatg agatacgcag
    11521 attttgctat gtatcaaatt aaaaatacaa tcaaggggga agttagtgaa tttgatatta
    11581 atatatataa taaggattca ttcttattga gtaatagaga agaattaaac aagttaattg
    11641 atggtcaatt agttgagtat gcatttcagc ctattgtaga ttgtaaaggt aaagtatttg
    11701 catatgaggc acttatgaga cctaaaataa aaacttttag ttcaccaata gatgtaatta
    11761 gattagctcg ttcacagtct aaattatatc aaattgagcg tattacatgg tttaaagcac
    11821 ttaaatcatt taaaaaatac aaagaaaaat ttggcgattg caaactgttc ttaaattcta
    11881 ttcctaataa taatttatca aaagtagatt ttgaggaaat tgaagattta tatggtgaat
    11941 atttaaatag agtagtatta gaaataacag agaatgataa gattaatgaa gattttattg
    12001 agaaaaagaa agcatatata gaccattgga atatagaaat tgctttagat gactttggga
    12061 caggttacaa cggagatgct gtactattat atataatgcc agactatgta aagattgata
    12121 tgtctattgt aagaggtatt gataaagatg aaaacagaca gaaaatatta aaaaatctta
    12181 tctcatattc taacgaaaga aatattaaag tgatatcaga aggtgtagaa acaaaaggtg
    12241 aaatggaaac actgattaat cttggagtag attatatgca gggttactat attagtaaac
    12301 catcatttat acctgaagat ataagtgaca aaattaaaaa agagctcaag atatgtcatg
    12361 aaaataggaa tgatgtggtt taatagagga aaaattaaat ttatttttat gaacttttag
    12421 tttataatta aaaagaaaat aatataatta taaattaagg tggtggagct aataatcaca
    12481 acaaacatag atataagaaa gttaaatgaa aatcaattag aagcagttga acatatagat
    12541 gggccttgca tgatacttgc agggcctggt tcaggtaaga ccagagtaat tacatataga
    12601 atagccaata tggttgtaaa caaaaatata gcaccaacaa gaatcttggc aataagtttt
    12661 accaaggcat cttcaataga aatgaaaaat agagctttga atttaagtga tgatataaga
    12721 cttaataagg taacctatgg tacttttcac tctgtatttt ttaaaattct aagatacttt
    12781 gaaagataca atttagacag tatatttgat gaaaagtcaa agcgaatgac aatcaaggca
    12841 atcctaaaaa gtttaaatat agagaatgct gatgatgatg agaatatagg acaagttata
    12901 aatgaaatct cctatgtaaa aaatgaactt atggataaaa atgaatttaa ttcagaagta
    12961 ttaacaaaag atgagttttt aaaagtatac aacttatacg aagaacaaaa atctaaagtt
    13021 aacaaaatag attttgatga tatgcttata agaacttatt atttactttt gaacaataag
    13081 tctgcactag aaatggttag aaatgtgtat aaatatatat tgatagatga atttcaagat
    13141 ataaataaag tacagtttga agttttaaag ttaatttgta gcccattaaa caatatattt
    13201 gcagttggag atgaagacca aagtatatat ggatttagag gtgctagacc agattttttg
    13261 cttgaatttg aacaatactt taataatact aaaaaaataa tattagatat aaattatagg
    13321 tctaaaagtg agatagtgta tactgcaaat agacttatcg acaaaaataa aaatagatat
    13381 gaaaaagtca ttaagtgtag tcagggggat ggaggaagtg ttacctacat ttctccacat
    13441 gattcagagg aagaagcctt atatattgcc aaggaaataa ttgacgaaat acaaaaagat
    13501 tatgtagagt attcagattt tgcagtaatt tatagaacaa atatacagtc aagagcatta
    13561 gtagatgtat ttatggatat gaggattcca tttgtagtaa aagactcagt aattacaata
    13621 tatgaccatt gggcaagtca agatatacta gcttatttaa gaataggtat taatccaaaa
    13681 tcaaataaag attggttgag aattataaac aagcctttta gatatatatc caaagacagt
    13741 ataaatatgg ttaaggatga aaaagacttt ataacagcat taataaataa gtgtaatctt
    13801 catcctaaac aagttaaaac aataaatgat ttggaaatag atttaagtta tttaaatact
    13861 ttaaatccta aaaatgcaat atcttatatt agaactagtc ttgattatga tagatacgtt
    13921 ttagattatt gtagcaacag aaagataaaa actaatggac ttgtagagat attaaatgaa
    13981 cttgagagtt cagcaactaa ttttaatact gttacagagt ttttagagca tattgataga
    14041 gtaaagactg agttaacgga aaataacaag aataagcaga ctgagggtgt catatttaca
    14101 actatgcata gtgcaaaagg attagaattt agaaatgttt atattatagg tgtaaatgaa
    14161 ggaacaatac ctcatgaaaa atcatatgat atttgtaagg aagagaaaaa agaagaacaa
    14221 ttagaagaag aaagaagact tatgtatgtt gctattacaa gagctgaaga aaagttatgt
    14281 ataagctcta ctttaaataa gtatggtaag aaagttgata aatcattatt tattaatgat
    14341 ataaaatctc caacgaaaaa agaaattgac agtattggtg taggggataa ggtataccat
    14401 aaaaaatttc atgaaggaga aataattaaa aaagatggaa ttatgtttac aataaagttt
    14461 aaagatagag agcgaatctt ggatttgaaa acttgtttat tgaagaatat aatttatact
    14521 atttaattta gaatctaaat ttagatagaa atataatgta ttatttatta tgtgcaagac
    14581 aaatagatat gtgtaaaatg tattatttaa cttattagaa aaagaaataa ggatttaata
    14641 tattatttat agttgtttag aaaaagcaac aatgtggaaa atattattta gtattattaa
    14701 agaaaagcaa caatgtgaaa gatattattt agtgtaattt aagaaaaagc aacaatgtga
    14761 aagatattat ttagtattat taaagaaaga gcaacagtgt gaaagatact atttagtatt
    14821 attaaagaaa aagcaacagt gtgaaagata ttatttagtg taatttaaga aaagcaacaa
    14881 tgtgaaagat attatttagt attgtttaag aaaaagcaac aatgtgaaag atattattta
    14941 gtattattta agaaatagct aaaaatatga aatatactat ttataattac aaaaataata
    15001 tcaataaata taaacagtag tatttagata atttacaagt aaaaattatt aaaaaaataa
    15061 aaaacttatt gacaaaaata ttataaggaa gtacaattgt attaacaatt taaggaaaca
    15121 aatccaatga tagagaaagt agcatatatg gatttacagc gagttagggg ttggtgtaag
    15181 cctagcaatg aagtctatgt gaagagagct ctggaggaga ttatcagaaa ctttagtatg
    15241 ataattggtt tacccgcctt aagggattga gaggataagt acttacttat caaaaagagt
    15301 ggtaacgcgg atataattcg tctcttagct gtaaagctaa gggacttttt tgatttaaaa
    15361 ataaaaatat ccatacagct taaatgctaa cagtcacaaa ttttgaaagt aatataagta
    15421 tttatcaata agagtggtaa cgcggtaaag tcgtctctta gtcattaaag actgagagac
    15481 tttttttgta actcgaaaca tttaagtatt aaaatctgag ggaaattata attaaaagag
    15541 aggggtagtt aaaatgaaag tatttaaaaa attattaagt ttaggattag tattaggatt
    15601 gacattatcg ctagtaggat gtagtggtgg aggagaaaaa acaaagttag aacaaataaa
    15661 agacaatgga aaattagttg ttggtactag tgcagaattt cctccatttg aatttcataa
    15721 ggtagtagat ggaaaagatt caataaaagg attcgatata atgttggctg aagaatttgc
    15781 aaaagagctt ggtgtaaagg ttgaaattaa ggatatgtca tttgatggat taataggtgc
    15841 tttaaatgca gaccaagttg atattgttct tgcaggtatg tctccaacac cagagagaga
    15901 aaagagtgtt gatttttcag aattatatta tttaagtaga aatgcagtta tagttaaaga
    15961 tgcagatata gacaaagtaa aaactgaaga tgatttaaag aaacttagag ttggagttca
    16021 agcaggaagt atccaagaag aatatgtagt taacacttta aaaatgacaa ctacaaaatc
    16081 tttaaaagca atacctgatt taattacaga attaaaaaat ggaaacatag atgcagttgt
    16141 tactaatgaa gcagtttctt taataaatgt taaaaaatat gatggaataa aaatggcaaa
    16201 tactgaagtt ggtaaagatg taacagaagg tatggcagca gcaatcaaaa aatctgacaa
    16261 taacaaagat tttatagaat tattaaacaa aaagataaaa gaattacaag atggtaagaa
    16321 gatagaagaa tttttaaatg aagcatctac tgaagctgct tcaaattagt aagaaagtta
    16381 tgtgggagat gaaattatga gtttagattt tagtttttta agtagatttg ggacttcttt
    16441 tttggaagga acaggtgtga cagtatcaat ttctcttgtg gcattatgct ttggatttat
    16501 aataggtata attatctgta tggcaaaaat atcaaagagc aaagtattaa gagcaatatc
    16561 atcaatctat attgaggttt taagagggac accattatta gtacagatat atatagtatg
    16621 gtttggttta cctcaattag gaataagatt ccctatgttg tttggtatac caagtgaatt
    16681 tatagctagt gcatttgcat tatcagtaaa ctctggtgca tacgtggcag agatacttag
    16741 atcaggtata caatcagttg ataatggaca aatggaagca agtagatcat taggattaaa
    16801 ttattggtca actatgagat atataataat acctcaagct ataaaaaata tattaccttc
    16861 attagcaaat gagtttatta cacttgtaaa agaatcttca ataatatctg taataggagt
    16921 tgttgagata atgcgtactg ctgatatagt aaaaaatgca gcatttagag cattagagcc
    16981 attaatagta gcagcagcaa tttactttgt tataacattt actctatcaa gattagttgg
    17041 attattagaa aagaaactat ctgtgtctaa ctagatgaga gcatgtttag catttaggga
    17101 aaacatagaa tagtaaaaag gaaagtgata atatgattac aataaaaaat ttaagtaaat
    17161 cttttggaga tttaaatgta ttaaaaaata tagacttaga aatcgctaaa ggcgaaataa
    17221 tggttatagt aggtccaagt ggttctggta aaagtacact tcttagatgt atgaatttac
    17281 tagaaatacc tacaggtgga gaaataatat ttgaaggaaa aaatttggtc gataaaaaaa
    17341 ctaatattga tgaggttaga caaaatatag gtatggtgtt tcaaaacttt aatttattcc
    17401 cacataagac tattttagat aatataacat tagcaccaat taaattaaaa aagatgacta
    17461 aggaagaagc agaaaaaaaa gcagaaattt tgttgagtag agttggtctt ttagataaaa
    17521 aagattcata tccatcacaa ttatctggag gacaaaagca aagaatagca atagctagag
    17581 cacttgctat ggaaccagat atgatgttgt ttgatgagcc aacatctgct cttgacccag
    17641 aaatggtaaa cgaagttttg gatgttataa aagaacttgc taaagaaggt atgacaatgg
    17701 caattgtaac tcatgagatg ggatttgcta aggaagttgc agatagagtt atttttatag
    17761 atggaggaag tatacttgaa gataatactc cagaagaagt tttcggaaat ccaaaacatg
    17821 aaagaacaaa agcattttta gcaaaagtgc tataatatat aaaaaggatg ttattgatat
    17881 tagaaattca atacatcctt ttttagtgat ggttaatatt aattttaaaa ttaaagttat
    17941 attaatatta actttatttt tacgattttt tgcagaaaaa aaaagagctc ggggtaagct
    18001 ctttttttcc accgaattaa tttccgttac taatccgatt tttaataaat ataaaatata
    18061 tccttatgaa agggtattgg gaatagatat attaactaac tagggttacc agggggataa
    18121 ccttaattta ttataacaaa atgcgacaca aaaatcaata ttttttttga aataaattat
    18181 aaaagttatt tttataacaa gtaagcttat aaatttaact tttatagtaa aaataag
//
LOCUS       DAMJWO010000085        18160 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.087, whole genome shotgun sequence.
ACCESSION   DAMJWO010000085 DAMJWO010000000
VERSION     DAMJWO010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18160
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.087"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            288..746
                     /locus_tag="PC366_003014"
     CDS             288..746
                     /locus_tag="PC366_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2578510.1"
                     /translation="MEFINFVSDKVIDLKMDCKTKEDFFKEIHNKVFDLGFVKEEFGE
                     KILARENVFPTGLNLGDYGVAIPHTDAEYIKEQFISVCTFNEPVVFSSMEDQDEKVPV
                     NLAFILGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLRTLKSL"
     gene            807..1082
                     /locus_tag="PC366_003015"
     CDS             807..1082
                     /locus_tag="PC366_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2578511.1"
                     /translation="MKKILVACGAGIATSTVVCDKVERLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            1141..2415
                     /locus_tag="PC366_003016"
     CDS             1141..2415
                     /locus_tag="PC366_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012951111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDF2578512.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKFVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLFLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPE
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            2545..3597
                     /locus_tag="PC366_003017"
     CDS             2545..3597
                     /locus_tag="PC366_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDF2578513.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DDHGMLGAKSFGAFAEYVNIKATNVLPIGDMDFEDAAMIEPLAVAMHGVLNIGVQVGD
                     AVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDIDPVEK
                     IKELTGGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            3597..4628
                     /locus_tag="PC366_003018"
     CDS             3597..4628
                     /locus_tag="PC366_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HDF2578514.1"
                     /translation="MKAVVKTKPGYDNVEVLEVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKDIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCPTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     EESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMASGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            4720..5532
                     /locus_tag="PC366_003019"
     CDS             4720..5532
                     /locus_tag="PC366_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDF2578515.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVNPVDDKFKSFGWNVIVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            5535..6455
                     /locus_tag="PC366_003020"
     CDS             5535..6455
                     /locus_tag="PC366_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HDF2578516.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILASIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGINVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTTEDIVKNIKELL"
     gene            6630..7076
                     /gene="rpiB"
                     /locus_tag="PC366_003021"
     CDS             6630..7076
                     /gene="rpiB"
                     /locus_tag="PC366_003021"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HDF2578517.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEVEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
     gene            7115..7780
                     /locus_tag="PC366_003022"
     CDS             7115..7780
                     /locus_tag="PC366_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDF2578518.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVKADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYISLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIEELKE
                     SIK"
     gene            7890..9392
                     /locus_tag="PC366_003023"
     CDS             7890..9392
                     /locus_tag="PC366_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HDF2578519.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVKKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSTVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGAIMITASHLPYYYNGLKFFTESGGLEKTNIKEMLDIAVKNDSVDYEEVNKKGEV
                     IVKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNNSNLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRFKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAQEEKEVRIGINKEDFRPYAEDILKDLDSHVKSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLKGL"
     gene            complement(9704..11296)
                     /locus_tag="PC366_003024"
     CDS             complement(9704..11296)
                     /locus_tag="PC366_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2578520.1"
                     /translation="MVTKLKNLIINDSKAKFILLLLLFLLVSILFEAVYDLNNNFSYN
                     INCYYKEFALPYFYFFGTPVHLSKVELEFVCIGIILSSFLLTILCFTLYKKNKQTKVK
                     FLENVISLFSKVKIELTLILTLILLTLRFHAFTSNKMFYNTNLIIYNFIIISIVYIIY
                     ENIKYNNYNLKDMSITYVFFSNLLSMYNKKTINKKLAIVFLISIVVQAIIQYLVLIFF
                     MYIYYSEAIAIVILFTLVNTVFHFYIYNFLSVKFNYINNISKNIKNIENGNLKYKLEV
                     IGDDEISTLAKSINNITGGLETAVDANIKNERMKAELITNVSHDLKTPLTSILSYVDM
                     LKNNDFDRETINDYINILDKKSQRLKLLIDDIFEASKLSSGDVEFNITKTDIRELLIQ
                     SIVEFEDKIQNSSLDFIIETPEYAVFTMIDGKKTWRVFENLICNILKYSMPNTRVYID
                     MFIKEENIILTFKNISNDKLNLKPEELIERFRRGDISRKTDGSGLGLSIAQNIIELEN
                     AHMEIIIDADLFKVMLTFRRVN"
     gene            complement(11265..11981)
                     /locus_tag="PC366_003025"
     CDS             complement(11265..11981)
                     /locus_tag="PC366_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2578521.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLRPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKIIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSREIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
     gene            complement(12522..13322)
                     /locus_tag="PC366_003026"
     CDS             complement(12522..13322)
                     /locus_tag="PC366_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDF2578522.1"
                     /translation="MTFKNKKFTINKYEILSIILVLCLILTGFSSYVNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTNIQK
                     SEYRNREFLASLNSLGVIRENIILLPETNTNGNTDFNYMEKIALTFEEKFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNVGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEYREGIGYKSDHKSFDKLLNNKDVPAILHTPNL"
     gene            complement(13637..14368)
                     /locus_tag="PC366_003027"
     CDS             complement(13637..14368)
                     /locus_tag="PC366_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578523.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIVGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLHDNPHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEVCAKKFPEFIKMEFGNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTGSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLKRLCFCSK"
     gene            complement(14355..15050)
                     /locus_tag="PC366_003028"
     CDS             complement(14355..15050)
                     /locus_tag="PC366_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2578524.1"
                     /translation="MLKIKNLSLDLPNFKLQENSLNINNHEYFVLLGASGSGKTLFLE
                     TLAGRYPSAKGNVSYKENLISNLPPENRNIGFVYQNFELFPNMNVEDNIRFPLKLRKI
                     PIDEQILKANHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAEPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKNKGESFFYEYI"
     gene            complement(15052..15843)
                     /locus_tag="PC366_003029"
     CDS             complement(15052..15843)
                     /locus_tag="PC366_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2578525.1"
                     /translation="MKNKFFTTLLTGFFAIVFFFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAITLSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKIFKLDFIFTKQGIVLAQVFVNLPLTIKILHTSLNESNEKMI
                     FVARTLGCNSWEAFRFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFISLTCLMLFEIFFNREVDKN"
     gene            complement(15853..16665)
                     /gene="modA"
                     /locus_tag="PC366_003030"
     CDS             complement(15853..16665)
                     /gene="modA"
                     /locus_tag="PC366_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2578526.1"
                     /translation="MFKKLSVLALAMIISLSITACNSKENKANDESNTKVTTADDSKE
                     KETLFVYSGAGLKKPMDEIAKKFEKENNVKVEYSYAGSAQLIAQIETSHKGDVFIVGS
                     EPIYSKAFEKELVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNKDGVKLILGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIESDEAKQIFKKYGFEPVK"
     gene            complement(17300..17500)
                     /locus_tag="PC366_003031"
     CDS             complement(17300..17500)
                     /locus_tag="PC366_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF2578527.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
     gene            complement(17725..17901)
                     /locus_tag="PC366_003032"
     CDS             complement(17725..17901)
                     /locus_tag="PC366_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578528.1"
                     /translation="MFRDKMDKCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGEKVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(17955..18044)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
BASE COUNT         6914 a         2250 c         2832 g         6164 t
ORIGIN      
        1 acataaaaaa ccatttgtaa aaaacaaaaa aatcatttct ctaacaaaaa aaaccacaaa
       61 aaatataaaa aagtatggct agttaagtga ttaacaagta aaaattgaaa taaaaatcaa
      121 aaaaaattta tcaatgaaag tcagctaaaa tcctggaaga gagcattatt ttcgggaaaa
      181 cattttcttt tgtttcacaa aaaaagccac tttttggcac gcaacatgct ttatataaag
      241 tcaagaaaaa ctaaggtata agacaaaggc aattaggagg tgtaaatatg gagtttataa
      301 attttgtaag tgataaagtt atagacctta aaatggattg taaaacgaaa gaagatttct
      361 ttaaagaaat acataataaa gtttttgatt taggctttgt aaaagaagaa tttggagaaa
      421 aaatattagc aagagaaaat gtatttccaa caggtttaaa tttaggtgat tatggagtag
      481 caataccaca tacagatgca gaatatatta aagagcaatt tatatcagtc tgtactttta
      541 atgaaccagt agtatttagt tctatggaag accaagatga aaaagtacct gtaaatttgg
      601 ctttcatatt aggacttaat caaccacaca gtcaattatc tgtattaaca gaattaatgg
      661 gaattatgca aaataaagag ttagttgata agttgatgag ttctactgat aaagaagaag
      721 ttttaaggac actaaagtct ttataaaaat aaaaaagtac taaaaataaa aaatataaaa
      781 ataaaaatta ttaggaggaa ataaaaatga aaaaaatatt agtagcatgt ggagcaggaa
      841 tagcaacatc aacagtagtt tgtgacaagg tagagagatt agttaaggaa aataatatac
      901 aagcagaagt tatacaatgc aaaatagctg aatgtgcaac aaagcaagaa ggagcagatt
      961 taatagtatc aacaactata ctaccaacaa cttataatat accagcaata aaagcaacag
     1021 catatataac tggagtaaat acagcagcat tagataaaaa aatattagat gctttaaaat
     1081 aatcctatca tagatacatt gaaataatat tttataaaac agaaaaagga ggatttataa
     1141 atggataaat tattagcagt agtacaatac attttaaata tgggaccgac agtaatacta
     1201 ccaataacaa ttgtagtact aggaatgata tttagaatta agtttacaaa agctttaaag
     1261 tcaggtctta caattggtat aggatttgtg ggtataaact tagttgtaaa cctattaaca
     1321 tcaacactag ggccagcggc tcaaggaatg gttgaaagat tcggacttaa tttaacagta
     1381 atagatgttg gttggccaac aacagcatca gcaacatggg cttcaccagt tgcaccaata
     1441 ttaataccag tttgtttatt agtaaactta ctattattat acttcaataa aacaaagata
     1501 ttaaacgttg atatatggaa ttattggcac tttatagtag caggtgcagt tggatatata
     1561 gtaacaggaa gttatgtttg ggctatattc tgtgcaatac taatggagtt attagtactg
     1621 tttattgcag aaaagacagc aaaaaatgtt caggagtttt atgatttaga aggtatagca
     1681 ttaccaactg gttcaacagc ttcatttgct ccacttggat atttagtagg taaatttgtt
     1741 gaaaaaatac caggaataaa taaaatacaa gcagacccag actctataca aaaaagattt
     1801 ggtatatttg gagaaccaat gatgatgggg attatactag gtataatact tggagcactt
     1861 gcgggatatg atgtagcagg aatattcaat gtaggtatat caatgggtgc agtaatgtta
     1921 cttatgccta gaatggttag aatattaatg gaaggtttaa ttccaatttc agaatcaata
     1981 agagatttct tacaagcaaa atatggagac agagaacttt atataggtct ggatgcagca
     2041 gtagcaacgg gacatccagc agttatatca acagctctta tacttgttcc tataacgttg
     2101 ttcttagcag ttatactacc aggaaacaaa gttttaccat ttggagactt agcgacaata
     2161 ccattttata tggcatttat agtgtgcttt agaaaaggta atatagttca atcagttata
     2221 acaggaacaa tagtaatagc tatatcactt tatatggcta caaactttgc agatgttcat
     2281 acacaattat tacaacaagc aaatatgatg ccagaaggaa caacaatggt tacaagtata
     2341 gatacaggtg gaaacttgct aaaatgggga atattgaaat tatctcaatt agtttcttca
     2401 tttggaatat tctaatatgt agttaataga gattactctt ttttagtaaa gtatgcgaaa
     2461 atttaacatt tagcagctac taaaaaagag taatattttt tataaatttt taaaaataca
     2521 aaatacaaga ggaggagatt tatcgtgaaa gcagcagtat tacatggcac aaatgatatg
     2581 agatttgaag atatagaaat aaaaccatgt gaaagtgatg aagtaaaaat aaaagttatg
     2641 gcagcaggaa tatgtgggtc agatcctcca agagtattaa aacattggaa atatccagtt
     2701 ccagctatac caggacatga gttttctgga gtaattgctg aagttggtaa ggatgtaaaa
     2761 aatgtaaaag ttggagatag agtagttgca attcctttta taccttgtaa tgaatgtgaa
     2821 tattgtaaaa gaggattatt ttcattgtgt gatgaccatg gaatgttagg agctaaaagt
     2881 tttggagctt ttgcagagta tgtaaatata aaagctacaa atgtacttcc aataggagat
     2941 atggactttg aagatgctgc aatgatagag ccactagcag ttgctatgca tggagtactt
     3001 aatataggtg ttcaagttgg agacgctgta gccgtaatgg gtagtggaac aatggggcag
     3061 ttggtaatac aaggacttaa aatagcagga gcaggaacaa ttatagcagt tgatatatct
     3121 gataataaat taagagaatc aaaggaatta ggggctgata taataatcaa tgctaaagat
     3181 attgacccag tagaaaaaat aaaagaactt actggtggaa aaggcgttga catagctctt
     3241 gaatgtgcag gttcaaaaat aactcaagaa caatgtttac ttataactaa aaagaaaagt
     3301 aagataggat ttttagggat agcatattca gatataactt tatcagaaga agcatttgaa
     3361 aatatattta gaaaagaact agaattaaaa ggtttttgga actcttattc tgcaccattt
     3421 ccaggacaag aatggactaa gggaatcaat ctagttaatg aaggaaagat aaaattaaaa
     3481 gaaatggtat ctcatagatt ctcacttgaa gatacttaca aagcatttga aatgataaga
     3541 gatagaaaag aagaatttaa caaaatatta attttaccac aaggggttga aaaataatga
     3601 aagcagtagt taaaactaaa ccaggctatg ataatgtaga agttttagaa gtagaagaac
     3661 caaaagctac aggagacaag gttaaaataa aagtagaata tagtggtata tgtggttcag
     3721 atatacattc atttaaaggt gaatatgcaa atataaaagc cccagtaaca ttaggtcatg
     3781 aattttctgg aattgttgta gaagtaggag aagatgttaa agatataaaa gtaggagata
     3841 gagttacatc agaaactact tttgcaactt gtgagaaatg tatatattgt gaaactaaag
     3901 attataactt atgcccaact agaaaaggta ttggtactca agtaaatgga agttttgctg
     3961 agtatgtact atcaagagaa gaaagcatac atgtacttcc tgaaaatgta tctttattat
     4021 cagcagccct tacagagcca ctagcttgtt gtgttcatgc agctcttgaa aagactacta
     4081 tagaaagttc tgatacagtt ttaataatag gaccagggcc aattggttta ttattagctc
     4141 aagttgttaa atctcaaggt gctacagtta taatgtctgg tgttacaaaa gataaggaaa
     4201 gattagaaat agctaaaaat cttggagtag atagaactgt aaatgtaatg gaagaaagtt
     4261 tggcagatgt agtgaatgaa atgactgatg gaaatggagt aaacaaagga tttgattgtt
     4321 ctgggtttat gccagcagtt aacgaagcct taagactgct tagaaaaaaa ggtactttcg
     4381 tacaagttgg aatctttgct aaaaaattaa atgaaatgga ccaagaagca ataatccaaa
     4441 gagagttaca atatatagga agtagatctc aaaagccaag ttcttggatt acagcattag
     4501 atttaatggc aagtgggaaa gtaaatacag aagctttagt tactagaact gttggtttag
     4561 acgaatttaa agaaggtatt acagctttaa tgaacgggga agaaataaaa gtagcagtaa
     4621 aatcttaaaa aaacatttgt attattttaa aaaaaattgt aaaatctact gtaggataaa
     4681 aaaatgtaag gtcttaaaaa ataacaggag gaagaaagta tgagcactct tagagatcat
     4741 tctaataata ttagaaaaaa cataataaaa atggttgcag aagctaaaag cggacatcca
     4801 ggtggttcat tatcaatagc tgatatgttg acagtattat attttgataa gatgaacgta
     4861 tgtgcagaaa atccaaaaat ggctgataga gatagatttg ttctatcaaa aggtcatgca
     4921 gcaccagctt tatatgctac attagcagaa aaaggatttt tcccagaaga agaattaata
     4981 acactaagaa aatttggttc taagttacaa ggtcacccag acatgaaaaa agtagcagga
     5041 atcgatatgt ctactggttc tcttggtcaa gggctatctg cagcaaatgg tatggcactt
     5101 gcaggaaaat tagataacaa agactataca gtatatacta tattaggtga tggagaaatc
     5161 caagaaggtc aaatatggga agctgcaatg acagcatcac attacaaatt agataattta
     5221 attgcatttg ttgacttaaa tggattacaa atagatggtt ctaatgaaga agtaatgaat
     5281 gtaaatccag tagatgacaa attcaaatct tttggatgga atgtaatagt aataaatgga
     5341 cattcttttg aagaaatagg aaatgcagtt gatgaagcta aaaaagttac aggaaaacca
     5401 actgtaataa tagctaaaac agtaaaaggt aaaggtgttt catttatgga aaataatgct
     5461 gcatggcatg gaacagctcc aaatgcagaa caagcagagc aagcattgaa agatttagaa
     5521 ggaggtctat aggaatggga atagcaacta gagaagctta cggacaagtg ttaaaagaac
     5581 ttgcagaaaa taaagatata gtagtattag atgcagattt aggaaaagct acaaaaagta
     5641 tatcatttaa agaagttgcc ccagatagat tttttgacat ggggatagca gaaggtgaca
     5701 tgattggtac agcagcaggt cttgctactt gtggaaaaat accttttgcg agtacttttg
     5761 caatatttgc agcaggaaga ggctatgagc aaataagaaa ctctgtagca tatccaaatt
     5821 taaatgtaaa aatagcagct actcatgcag gtgtaacagt aggtgaagat ggtggtagcc
     5881 atcaagctat agaggatata tctctaatga gaggtatacc aaatatggtt gtattaaatc
     5941 cagcagatgc tttagaagca agacaagcta ttcttgcatc tattgattat aatggacctg
     6001 tttatataag attaggtaga gctgcaactc ctgatgtaaa cagtgaaaat tataaatttg
     6061 aaataggaaa aggaactgtt ttaagagaag gttctgacat aacagtaata gctacaggaa
     6121 taatggtagc aaaagcctta gaagcagcag aagaacttgc taaagaaggt ataaatgtag
     6181 aagttgttaa tatatctaca ataaaaccat tagatgaagc attaataaaa gaaactgcta
     6241 agaaaactgg aaaagtagtt acagcagagg agcacagtat aataggtggt ttaggttcag
     6301 ctgtatgtga agctttagca gaaactaaag atgtagtagt tagaagaatt ggtgttaaag
     6361 atgtatttgg tcaatcaggt acaccagctg atttattaaa acactatggt ttaactacag
     6421 aagatatagt aaaaaatata aaagagttgt tatagatata aatatatcta aataacaaat
     6481 tgatttgaca taagtcaatt aaagctgtct taaaaataga aagaaatttc tacaatggga
     6541 cagctttatt tttacaatac tttattttta tgataattat aaaatagtct gaaagtaatc
     6601 aaaaaaatta taaaaagagg tgctatttaa tgaaaatatc tattggatgt gaccatggtg
     6661 gttatgaatt aaaggaatat ataaaggaaa atttaataaa taaaggtata gaagttgaag
     6721 atgtgggtac aaattcaaaa gaaagtgtag attttccaat atatgcaaaa aaggtaagtc
     6781 aaaatgttca aagtaaaaaa tctgatttag gcatactttg ttgtggaaca ggaataggca
     6841 tgtctattgc agcaaataag tttaaaggaa tcagagcagc tgttgtttct gactgttttt
     6901 cagctaaggc aactagagaa cacaataata caaatgtact ttgtttagga gaaagagtta
     6961 ttgggaaagg attagcaatg agaattgttg aagaatggtt aaattcaagt tataatggag
     7021 aaagacatgc aagaagatta caaatgattg atgatataga aaaagaaaat ttataaatat
     7081 atataatata taatttataa caagggggag cgttatgtct attatttgtg cttcaataat
     7141 gtgtgcagac caaatgaagt taaaagagga attagaagct cttgaagaag caggtgtaaa
     7201 attacttcat tgtgatgtta tggatggaat atttgttaaa aacttggcta tgggaccaga
     7261 gttattaaaa tcaataagtg aaaatacaac aataccttta gacatacact tagccacaga
     7321 aactccagat aaatatattg atatgatgtc ttatataaag ccaaaatata tttcttttca
     7381 tgtagaatca agtacaaatg taaaagctga tatacaaaag ttaagaaatt atggtatagg
     7441 gccagtgtta gcaataagcc ctcaaacaag tgtggataaa atagaagaat atataagttt
     7501 agttgagggt atcttagtaa tgacagtaaa tccagggttt gcaggtcaaa agtttaatct
     7561 ttctgtattg gataagttgg ataaacttac agagatacta aaagattatg ataatcctcc
     7621 atttatagag gttgatggaa atataaataa ggatactatt aaacttatga atggtaaaaa
     7681 agtagatata tatgttgttg gtacttcagc tttatttaat gataagcctc caatttcata
     7741 taaagataaa atagaagaac taaaagaaag tataaagtaa ccatgtaata aaattataat
     7801 atgtttctgt ttaatagtaa aaatttaggt ggaaacaaga aattttataa tatttaataa
     7861 aaattttggt tgagtaagga gaatttttta tgggagacct atataaacta caaaatggta
     7921 ctgatattag aggaatagcg tatgaaaatg attctaaaga agttaaccta actgtagaag
     7981 aagtaaaaaa aatagctaaa gcgtttcata tttggctaaa agaaaagact aagaaagata
     8041 aagtaactgt tgccatagga actgattcta ggataacagg aagccaattt agaagtactg
     8101 ttattgaaac tttaactaat gatgattgta atgtaattga ttgtgagatt gctacaactc
     8161 cagctatgtt tatgacaact attatggatg gatacaattc tgatggggcg attatgatta
     8221 cagcaagtca cttaccttat tactataatg gtttaaagtt tttcacagaa agtggaggtt
     8281 tagaaaaaac taatataaaa gagatgttgg atatagctgt taaaaatgat agtgtagact
     8341 atgaggaagt aaataaaaaa ggtgaagtta tagtaaaaaa tttaatagaa gattattcta
     8401 atttattgat agataaaatt agaaaaggtg taaattcaag taaaaattat gaaaagcctt
     8461 tttctgggct taagatattg gttgatgcag gaaatggagc tggtggattc tttgctgaaa
     8521 aagttttaca catactggga gcagatacga caggcagtca gtttttgaac ccagatggta
     8581 tgttcccaaa tcatatacct aatcccgaaa acaaagaagc aatggaaagc atatgtaaag
     8641 ctgtgttgga taataatagc aacctaggaa taatctttga tacagatgta gacagagctg
     8701 ctattgtagg taaaaatggc aaaccaataa ataaaaatgc tcttatagct gttatatcat
     8761 caatagtatt agaagaacat ccaaaaacag ctatagtaac agattcgatt acttctgaag
     8821 gacttgctaa atttataaat gaattacaag gaagacatca tagatttaaa agaggatata
     8881 aaaatgtaat aaatgaagct ataagattga atagtgaagg tgaagagtgc catttagcta
     8941 tagaaacgtc tggacatgct gctttaaaag aaaattattt cttagatgat ggggcatatt
     9001 taatagctaa aattttaata aaagtagcaa agctatcctt ggaaggaaag actatagaag
     9061 aattgataga aaaccttgaa gaagctcaag aagagaaaga agttagaata ggcattaaca
     9121 aagaagattt tagaccatat gcagaggata tattaaaaga tttagattct catgttaaga
     9181 gtattgatgg atggtctgta gcaccaaata attttgaagg aataagagtt aattgtgatg
     9241 aatcaaatgg agatggatgg tttttactta gaatatcact acatgaacca ttactagctt
     9301 taaatattga atcaaataaa attggtggag cagaacaaat ttattctaag ttaaaacttt
     9361 tcttagaaaa atatgattta aaaggtcttt agggtaaata gaaagaatat atttatatta
     9421 aagaacaaat gtaaatttgt acctaagatt acaaatatta caaaattgta atcttaggta
     9481 acagagatgt aactgattat ggaaacacta tgtgatatta tagatacaga gagatgaaat
     9541 atgtgatgaa ttatagagaa atataattta aaatgtatta atatcacacc aaaaaggtat
     9601 aatcaaaaaa tatgtaaata taaaccccaa catttagaaa aagacctcta aggaggtttt
     9661 tttcttgttt aaataactta aaatatattt ttatattaat atatcaatta actcttctaa
     9721 aagtaagcat taccttaaat aaatcagcat ctataattat ttccatgtgt gcattttcta
     9781 attcaattat attttgagca attgataaac caagaccaga gccatctgtt tttctagata
     9841 tatcacccct tctaaatctt tctattaact cttctggctt tagatttagt ttatcatttg
     9901 aaatattttt aaacgttaat attatatttt cttcctttat aaacatatct atatagaccc
     9961 tagtgttagg catagagtat tttagtatat tgcaaattag attctcaaaa actctccaag
    10021 tttttttacc atctatcatg gtaaaaacag catattcagg tgtttctatt ataaaatcta
    10081 aactgctatt ttgaattttg tcttcaaact ctacaatact ttgaattaaa agttctctta
    10141 tatcggtttt tgttatatta aattctacat ctccactact tagcttagat gcttcaaata
    10201 tgtcatctat taataatttt aatctttgtg attttttatc taaaatattt atatagtcat
    10261 ttatagtctc tctgtcaaag tcattatttt ttaacatatc aacatagctt aatatagatg
    10321 taagtggagt ttttaagtca tgagatacgt ttgtgataag ctctgccttc atcctttcat
    10381 tttttatatt agcatctaca gcagtttcaa gaccacctgt tatattattt atacttttgg
    10441 ctaaagtaga tatttcatca tctcctataa cttctaattt atactttaaa ttgccatttt
    10501 ctatattttt tatatttttt gatatgttat ttatgtaatt aaacttaaca gataaaaagt
    10561 tgtatatata aaaatgaaaa actgtgttta caagtgtaaa taaaattact atagctattg
    10621 cctcagaata atatatatac ataaagaata tcaaaacaag atattggata atagcttgta
    10681 caactataga tattaaaaat actatagcta attttttatt tatagttttt ttattataca
    10741 tactaagtaa gtttgaaaag aatacatatg ttatagacat atcttttaga ttatagttat
    10801 tatatttaat attttcatat attatataga ctatagatat aattataaaa ttgtagatta
    10861 ttaaattagt gttgtaaaac attttattac ttgtaaatgc atgaaacctt aaggttaata
    10921 gtatcaaagt taatataagt gtaagttcta tttttacctt agaaaaaagg cttatgacat
    10981 tctctaagaa tttgacttta gtctgtttat tttttttata caatgtaaaa catagtatag
    11041 tcaataaaaa acttgataat ataataccta tgcagacaaa ctctaattct acttttgaca
    11101 aatgtacagg agtaccgaaa aaataaaaat aagggagagc aaactcttta taataacaat
    11161 taatattata agaaaagtta ttattcaaat cataaactgc ttcaaataat atagaaacta
    11221 atagaaacag taataataat aaaataaatt ttgctttaga atcattaata attaagtttt
    11281 tcaattttgt aaccaatgcc ccacaccacc tttaaatatt ttggttcttt tggattaatt
    11341 tcaatttttt ctctaattct tctaatatga acagcaatag ttctctcaca actataagca
    11401 tcttcattcc agacattttc ataaatttca cgggaagaga aaattttacc ttttcgtgac
    11461 ataagaagtg taagtatttt atattcaagt ggtgtcattt taatttcctc accatctaaa
    11521 gaaactattt ttgtatctgt atttagctct aggccaccac tttttagaat ataattagta
    11581 tcatttgagt tatttgtatt actaaaatca cctaaattta tataccttct aagttgagat
    11641 tttactcgag cagtaagttc tagtggatta aatggtttag ttatatagtc atcagcaccc
    11701 atattaagac ctataatttt gtccatatct tctgattttg cagataagag aattattggt
    11761 atattccttt tttctcttat tttaagtgta gttttaagcc catctaaatt gggcatcatt
    11821 acatccatta ttattaactt aatatcattt tcgattagta tgtccaatgc ttcaagtcca
    11881 tcatatgcct ttaaaacatt aaagttatca ggtctcaaat agaactctat agcatcaact
    11941 atctctctat catcatctac aaccaatata ttttgattca atttattaac ccccttgaaa
    12001 ttttattttt aaccaatttt tattttatac caaaaagagg tattagaaaa cagtaagccc
    12061 gttcattatg aaataaaaac tagtactttt aatatattgt caatgcatat agtaaattta
    12121 aaagtataga cgcccatatt aatctgaagg taaaagttta tgaaaatatc tagggtaatc
    12181 tatcacactc cttatgttat tttgggttta ttaatttttt aggtttaaac atatattaac
    12241 aaatataaat aacaaatgag tttcataatt attaagaatt tataacaaat atttatttta
    12301 atgtagttta atataaatag gtagtttaat gtagatatgt ataaagtatt taataaggct
    12361 tataggtttt aatgatgata tctttatata ttttaagaga tgatgaaatt agatatgggt
    12421 aatagttgaa tgagaaaaag tagtatagca caaaaagtgc tatatcacaa aatctcaaat
    12481 aatttccttc ttataactta aattaaaaga ataaatattt cttataaatt aggtgtatga
    12541 agtatagcag gaacatcttt attatttaat aacttatcaa atgatttatg gtcagactta
    12601 tagccaatac cttctctata ttctaattca tcaacaattt tgtattgttg acaggcattt
    12661 ttaacctttt catagtcttc agtagaatga gctttataaa ctatcttatt attaaaagtt
    12721 attttatcag caaatttagg ttttacaaaa tatttagcat cttttatttt accaacatta
    12781 tataaatttt ggataacaga accatttttt aaatgttgta aatggtcatc taacttataa
    12841 gtatgtgcta tatgagttac atttttaaat ttttcttcaa atgtaagagc aattttttcc
    12901 atgtaattga agtcagtatt accatttgta tttgtttctg gtaataatat tatattttcc
    12961 cttattacac caaggctatt aagagaagct aaaaattctc tatttctata ttctgatttt
    13021 tgtatatttg ttaggttttc atatttttta tatttatcaa agacggatat accacatcca
    13081 gtagatacta aaactacaaa tacatgattt tttcctcttt cttttatagc attaacaata
    13141 gcactcccag cccacaacac ttcatcatct tgatgctgaa catagaagac aacataatct
    13201 ttaaattttt tatgactata attcacatag ctactaaaac cggttaaaat caagcataaa
    13261 actagaataa tagatagaat ttcatattta tttatagtaa attttttatt cttaaatgtc
    13321 atttaatcat ctcctgaaaa gttgtcttag ttatattatc aaacaaagta ctaaaaatta
    13381 tttcttaaat gctgaaaaat atagagtaga ttaatggaat aaaatttttt ttattagttt
    13441 aaaataaaga aaacatttat gtataagact aatcaaaata ttaataattg ataggaattg
    13501 agatttaaag ggattgtaca tttattcggg attcatttta atagaatttt actttagtac
    13561 ttagaataaa agtaataact ttttaaattt aaagagtaca catatatatt tgtgtactcc
    13621 ttgatgatat gattgcttat ttactacaaa aacagagtct ttttaaacct aaaatatttg
    13681 atgcaccagc tatcgtagtt ccataatagt aaactggttt gttaagtgat agaaaattta
    13741 taattgagtt attacataat gtacttcctg tgcaaatcac taaatcagcc caagatatta
    13801 catcttcata atctcgtata ccatcttcaa tcttaacatt atattgaata gtatccacaa
    13861 attcaggatt taaatctaat actcttgttt cgaaaaagtc cttaatatta tcaattatgg
    13921 ctggttgata tcctataatt gctacttttg gattaccaaa ttccattttt ataaactcag
    13981 ggaatttttt tgcacatacc tctggctcgt tatttttaca atgaatggtt ctatccgtct
    14041 tgcctaagta tttcataact gcatttaatg atgctataaa aagacttcta tcatgaggat
    14101 tgtcatgtaa atctaatgat aatatgtctt ttaaagaacc ttcaaatgta gatggagtag
    14161 aagtaaatgc ttgtccttta gctcctttaa agtcagcttc aagcattatt tctttaccaa
    14221 ctataattgg gaaatcttta cgcttagtat ttccaattgc ttcttttgaa gatagagatt
    14281 tggacacaat acttatcata tccatattta aattatattt atcgacttgt actaatagat
    14341 aatctctcaa aatatcaaat atattcatag aaaaaagatt ctcctttatt ttttatttct
    14401 tcatttaaat caaaaatatg atttattttt ccattgttca ttattcctat cttatgagca
    14461 aaaaacattg cttcagaaat atcatgagta acatgaatca ctgttggttt gtattttatg
    14521 tagacatcct tcaaaatttt gcttatatgt ttttttgtaa tataatccaa tgaactcata
    14581 ggttcatcta aaagtaatat atcaggttca gctattaagg cacgtgcaaa agcaactcgt
    14641 tgcttttcgc ctccacttaa atttttagga tacctatttt ttatatcttc tatctgcatt
    14701 aatttagaca agtggttagc cttaagaatc tgttcatcta taggtatttt tcttaattta
    14761 agtggaaacc ttatattatc ttcaacattc atatttggaa ataattcaaa attttgatat
    14821 acaaatccta tatttctatt ttctggaggt aagtttgata ttaaattttc tttgtatgat
    14881 acatttcctt tagcagatgg atatcttcct gctaatgttt ctaggaatag agttttacct
    14941 gacccactag ctcctaataa aacaaagtat tcatgattat taatatttaa actattttct
    15001 tgtaatttaa aattaggtaa atcaagagat aaatttttta tttttaacat attaattctt
    15061 atcaacctct ctattaaaaa atatctcaaa aagcatcaag catgtaagtg agataaatat
    15121 caaaattaca gctattccga ttgcaatgtc tatatcacca gtagacatat ttaaatatat
    15181 agatgtagga ataatttcag ttttcatacg tgtagaacct gctatcatag ctactgcacc
    15241 aaattcacca agtgctcttg accaagtcat tacagttgca gatatgattc cagtttttag
    15301 atttggaaga attataaatc taaatgcttc ccaactatta catccaaggg tacgtgcaac
    15361 aaatatcatc ttttcattac tttcatttag tgaagtgtga agtattttaa tagtaagtgg
    15421 aagatttaca aatacttgtg ctaaaactat accttgcttt gtaaatataa aatcaagctt
    15481 aaaaatctta taaatggaat ctccaatccc cattcttcca aacaaaagta aaagagcaat
    15541 tcctgatact aagtgtggaa gagacatagg gagatttatt atctgtataa tcagtttttt
    15601 aaatggtaat ttagtaatat gtaaaaaata tgctactgga atagctaata aaaggcatac
    15661 tatagtagat attaaagatg ttttaatact aagtgttatt gcatactgta cttccacgga
    15721 ttttaagcat ataggaacat aacttatccc tttaatgatt aacataagaa gtggtgatac
    15781 aataaaaaaa aagactatag caaaaaatcc agtaagtagt gtagtaaaaa atttattttt
    15841 caagtttaat cactacttaa caggttcaaa accatatttt ttaaatatct gtttagcttc
    15901 atctgactct atataattta taaatttatt agctaaatct tttttatcac tatagtttac
    15961 gattcctgct gatatgagtt ggtctatatt tttatcttgg gcaatttcta taacttctac
    16021 atcttcattg ccaaagaccg aatcttttgt ggctattgta gcatcagctt tacttgatgt
    16081 taactgtaca atcatttcat ttacagttgc agctgtagag acaacattat catttataga
    16141 ttttaaatta tttttttcaa gtattttttg tgtagtctta cctatagcat tagactcttt
    16201 gtctcccaaa ataagtttaa ctccatcttt atttaagtct tccaattttt gaatattagc
    16261 tggatttcct ttaggtacaa ctattgcagg tgtatgatgt gcaaccgttt tatgttcacc
    16321 tacaagttct ttttcaaagg cctttgaata aattggttca gaaccaacaa taaatacgtc
    16381 tcctttgtga cttgtctcaa tttgagctat tagctgtgca gaacctgcat agctatattc
    16441 aactttgaca ttattttctt tctcaaattt ttttgctatt tcatccattg gtttctttaa
    16501 acctgcccct gaatagacaa aaagagtctc tttttctttt gaatcatcag ctgttgtcac
    16561 tttagtatta gattcatcat tagctttgtt ttctttagaa ttacatgcag taatacttaa
    16621 tgaaataatc atagctaaag ctagtactga aagtttttta aacataagat attccccctt
    16681 agtaaattag tgtaaattct tttttagtat atcatactaa gaaaacgatg tctaagtttt
    16741 tgttatgttt tataatgttt tgttatgttt tattatgtat agttaagaaa aaatctattt
    16801 ataatgtcat ttccataggt agttatttta tttttaattt ttattaatac tttaaagtat
    16861 tttaaattta aaaacttaaa tcaaattaac ttattgtaga ttttttactt tttaactaat
    16921 tttatattta ttatatttca gtgaaaaaat agaacattga aacatataga tatgttttaa
    16981 ttgcttttta ttaacaaatt actaaaagtg ttatatcaga attgaataca aaagaaagag
    17041 tatgtattta tgagatagtt gaaaattttg atgtgccaca actaaaatta ttatattact
    17101 atatattcta attaaaagag tacttgtagg tttaagtaca tactttataa atatattttt
    17161 gtcagattta ttttataaaa agtatttaga ctaagtatta tttttaagta ttttcttgtt
    17221 gaagttattt tttccttttt tacaaaatgc gtaaataaaa aaaagactct taaaagagtc
    17281 tttccgaaaa atctatatat tataatatag ttatattttc tgcttgagga cctctagcgc
    17341 ctttaactat atcaaagctt actttttgac cttcttctaa tgatttaaat cctgaagttt
    17401 gtatagctga gaaatgagca aatacgtcat ctccactttc cattgatata aatccaaatc
    17461 ctttttcatt attaaaccat tttactattc cattattcat taaaaatact cctattaacc
    17521 tatatcaaga tatacttgat ttacttgtgt attaccacaa atactattat atcatagatt
    17581 aacataaatg tctatttaat tataattttt agttaacatt tttatttatt cttaatatga
    17641 aaataaattt aaacatttta tattaccaat atattaatgt aaatgtagat aaaactaaaa
    17701 agggttttct agaagaaaat ctgtctaatt atacttactt accaatacca tcacttgatg
    17761 caagcaagat tccacaactt tttctccgta ctctaatata aaatcatcta actgtgtatc
    17821 tataaaatca caataatcat atgaactacc aatataagca gttagcatat gtgtacattt
    17881 atccatttta tctctaaaca taatgtattt atccccctaa aaaactttca tgaaaaacaa
    17941 aaagaaaata tctttttggc aactggctga cataacttat tttataagcg ttagtcccta
    18001 tagctttgcg tcactaaatt tctctagttt tgccgattta gttttattct acagattaat
    18061 aatacaatag aattagctat tattcaacat atctagctga aaaattaata aatttatata
    18121 tgaacgttaa attatttgaa aaaataaaaa gcccctctgt
//
LOCUS       DAMJWO010000086        17372 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.088, whole genome shotgun sequence.
ACCESSION   DAMJWO010000086 DAMJWO010000000
VERSION     DAMJWO010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17372
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.088"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            116..862
                     /locus_tag="PC366_003033"
     CDS             116..862
                     /locus_tag="PC366_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HDF2578529.1"
                     /translation="MKIENLSIDDIKRGYIFNDDLNCYSCIKCTKTYEVGEIYKIGNR
                     FFEASKAIELHMELEHSDYLEQLLNSDSKYNTLTENQKQLFQLFISDLPDKEIAKQVG
                     VSTSTIRHQKFIFREKAKQAKLYLALYESVFEDKSNKSSTIIPIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKKYSEKEVNQILES
                     IYDDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            924..1598
                     /locus_tag="PC366_003034"
     CDS             924..1598
                     /locus_tag="PC366_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2578530.1"
                     /translation="MNDELKSILYNKGVDIVRFVDISEFPINQTQGFSKAILFCIGLS
                     KKFITDIYNNLPTDSDEFLEKEEKVEELADWISKYIQNKGYRAYSQSEKNNLEHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RYPLIDSKCLNCNVCVENCPAKAIHGNEWTLPGKRESIIDVSKCFCALRCMMSCPWSL
                     RYANQK"
     gene            1966..3312
                     /locus_tag="PC366_003035"
     CDS             1966..3312
                     /locus_tag="PC366_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HDF2578531.1"
                     /translation="MEIETKTPDWINVLELNSKIDITWKYDVSNMIQDIVSDKSLEGS
                     IIYFPKGNYLFEKGIKISQQITLQGDSYYGGDNQVSNLDKKQSIVGTTNFITRGVSNI
                     SIITLEGTSQCIKNINFYYDSHDIEKIPPKNVSAITEYGETQGLFHFEHLFISGFSGI
                     GIEIPYYSTGNDIIVSSCGLGMRLGEKSMLSSSKIYECKNGMEITTGVSLNNVRIEEI
                     REIGINNKGFGFNLIMNLMVDQCGYCGFMFEKMCYSQITARITKCGQYYKSVDYNTYE
                     NMEDRKEEAYSIFYGDILENCNIVLMNSNIDTLENDSLDEHKIYVIKANETNKVMLTC
                     YAEADELIQCAKGNLLLENGENTYKFYNGEICSVGGVQISDIDEKDLIKIIENTLYID
                     DKGKYLMVPRLKKNTVIYSVLDSIEEINKLHGGIWEQIDVKVLAGESMYYYKKIKD"
     gene            3339..4739
                     /locus_tag="PC366_003036"
     CDS             3339..4739
                     /locus_tag="PC366_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HDF2578532.1"
                     /translation="MEESIIIKDISGWINVLDYGICNDETKDVSSKLQEIIDAAPEDS
                     IIYFPKGKYLFESGVKIKKRLTLCGDSYILANVPKNTAGVTQFTFKGKKNPKSENIAI
                     ITAKSVRHCIKSICFYSDSCDRDMTSNHEPPTDGKPRFHHNVIINYRNISAIVCEDKQ
                     GEPGHYENLFFSGFSGIALDMPNNSTANDITVFTSGLGISTGENSTIANSKVWGCVDG
                     MIISTGTFINGMRVEEIKKVGIKNIGRGLNFITNITIDQCGYCGVWFDSISNVQISGN
                     ITRCGQYYYDVSYDNYLMLDNRVKEAYSLFYGNLLESSNIVLSNTNKDNWEDFKEDKH
                     KVYLVEALETKNVLLTCNIDATDWIVKSEKGNLTYNNMRQTVIFYDGKLSSINGIGIS
                     DEDYGDKVKIKKGNIYINSKDKVIKMHKPEVGDIMSTIIKDENILSAHYGGTWGKIGE
                     KIEFGITVHYYKLIEK"
     gene            4949..6385
                     /locus_tag="PC366_003037"
     CDS             4949..6385
                     /locus_tag="PC366_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HDF2578533.1"
                     /translation="MEGRTGIKDGRWINVVERGIKNDGSYNIGPDLQDIIDEIETDFC
                     VLYFPKGKYLFTSGVKINKEIVLQGDSNSPTETTQFITRGVENMSIITLTGKKQCIKN
                     INFYSDSCEIQVNEEPPTKGNPKYHYEMIINKNEKNVEMNNVSAILYDNSKNMIKGLG
                     HYENIYISGFSGTGIRIPYYSIVNDITVSSCGLGIDTGIDTIISNSRISKCQNGMRIR
                     TGTSINNVRIEKIQKVGLISSQVKDYEGYGSYKINNITIDQCGYCGFLFDSVKGSYFS
                     GIIRRCGQYYYNTDYDTYLSIKDRVEEAYSLFYGNYFTECNIDLVSDNKDNWDDGLEY
                     KHKVYVFKTLQIPKLTLRCNIDAYDYIVKSVHGGGNLMLKNNFNNYIFIDSSSPEVIN
                     GINFNYQKNGNLLRLNNGKLSYKNGKEETAIFRPNYGLIVASTDSECEQIETSYGGKW
                     EKLGSEVIGKETVYYYKHHEPDKTNQIK"
     gene            6729..7673
                     /locus_tag="PC366_003038"
     CDS             6729..7673
                     /locus_tag="PC366_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HDF2578534.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLKEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMLYDLNKLKDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELSRKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEISKIAHKHGIILEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEDNKLLIDTLRDDAKISIRDMKTIKVDKNKQISIFD"
     gene            7842..8774
                     /locus_tag="PC366_003039"
     CDS             7842..8774
                     /locus_tag="PC366_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HDF2578535.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGFIGFILY
                     AIYIVKIILLRKGVKEQLENPLISSTFPTITMATMIFATYIKPLSLELSIMIWSIGIV
                     GHLVLIVLFSKKFLVKFSIKTVFPSWYIVYVGIVAASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLMNGYLTKSGHFISWISY
                     ASKLEEIIATVIILYVLVLFIIYLSKSETTSKAK"
     gene            8879..9346
                     /locus_tag="PC366_003040"
     CDS             8879..9346
                     /locus_tag="PC366_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C_GCAxxG_C_C family protein"
                     /protein_id="HDF2578536.1"
                     /translation="MKTKEEYLKEVRNISEEYFRKGEFFCSEAVLQTINDALGQPLSP
                     EITKLASGFPIGLGKAQCLCGAISGGEMALGIVYGRVHGETMNPKMFEHAKGLHDYIK
                     KEYGATCCRAITKKWDGDNFMSPERKEHCIKITGQVTEWVADKLIEDEKLNIK"
     gene            complement(9590..10444)
                     /locus_tag="PC366_003041"
     CDS             complement(9590..10444)
                     /locus_tag="PC366_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009912760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HDF2578537.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMISGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVYRENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKEKKNKKEWLAIFIGIILIMSG
                     VFMLSIIK"
     gene            10610..12574
                     /locus_tag="PC366_003042"
     CDS             10610..12574
                     /locus_tag="PC366_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2578538.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIADDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLIRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLSEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIDILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKGEYIEESLYIGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVAADQHRDTNELKNTSTNPCETSTNNISNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDDECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSCCTSKK
                     YKSFRNLIFEENILLNIEASNYEDAIKYITDNLIKKGFVKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLLEESI"
     gene            12574..13035
                     /locus_tag="PC366_003043"
     CDS             12574..13035
                     /locus_tag="PC366_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2578539.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSDAVKKSSIIFAKTKHKIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            13038..13358
                     /locus_tag="PC366_003044"
     CDS             13038..13358
                     /locus_tag="PC366_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF2578540.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            13374..14474
                     /locus_tag="PC366_003045"
     CDS             13374..14474
                     /locus_tag="PC366_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF2578541.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIAVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDEAEWES"
     gene            14594..17194
                     /locus_tag="PC366_003046"
     CDS             14594..17194
                     /locus_tag="PC366_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HDF2578542.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLHKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKHVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSLKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKIKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARIH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLINTWKKLLEGQAHD
                     SLAGCVTDTVTDYILHRIREANEICDSIENTIVKKISEGLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDATIIEETYVKPRENVLEETPAGNVFIEESGYYILKVR
                     INVQLPALGYKVVSFESSDKEMVSLDKSNDTFISNDNYKIIYEDGSLNLQLKDGTYIS
                     NFLILKDSGNAGDTYDFSPLKNDEDIKLSFDRVYTEKTLGYEKLVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVSIVLSKENPLMDVKLCVDNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRENGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTVFTRGIKEYQHIEDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQMLKKLEFSFAIYMDSKS
                     FDELEIANLTHNYLRECVNYQLQDYNFFLYRIDNKIQKSIVNKTVSRELEIISLPEKY
                     LISACYPSYYSKDKFIIRVENPSSNRMILDEQIFKNRNGKIVNAIEDVEEEQVYEIAP
                     FDVISILLDL"
BASE COUNT         6919 a         1789 c         2996 g         5668 t
ORIGIN      
        1 tcaaattaat aaataattag aattgataaa caaaaaataa aaatgttgat tatattaata
       61 aactttaata taatatattt atgaaaaatg taaattgtga aatggaggta gtaacatgaa
      121 aattgaaaat ctttctattg atgatattaa acgaggctat atatttaatg atgatttaaa
      181 ttgttatagt tgcattaaat gtacaaaaac atatgaggta ggagaaatat ataaaatagg
      241 taatagattc tttgaagctt caaaagctat tgaacttcat atggaattag aacatagtga
      301 ttatttagag caattgctta atagtgattc aaagtacaac acattgactg aaaatcaaaa
      361 acaattattt caattattta ttagtgattt accagataag gagatagcaa aacaggttgg
      421 agtatccaca tctactatac gccatcaaaa atttattttc agagaaaaag caaaacaggc
      481 taagctctat ttagcactat atgaatctgt atttgaagat aaatctaata aaagtagtac
      541 tataatacca atccatgaac atgctcgaat ggtagatgaa agatatgtag taactgaaga
      601 agagagaaaa cacattttgg atacatcatt tgaaagtatg aatcctttaa aattaaaagt
      661 attttcttca aaagaaaaga aaaaggtcgt aattttatct aagattttgg aacaatttga
      721 acgtgggaag aaatattcag aaaaggaagt taatcagatt ttagaatcta tatatgatga
      781 ttttgcaaca attagaagat atttaattga gtatggcttt atgagtagaa ataaagaatg
      841 tacaaagtat tggttaacat aattaaaata ataaatttta ctaatgtgta atgttatttt
      901 tatctagggg ggaggagtta aatatgaatg atgaattaaa atctatttta tacaataaag
      961 gtgtagacat tgttcgcttt gttgatatat ctgaatttcc aataaatcaa acacaaggtt
     1021 tttctaaagc aattttattt tgtatagggt tatcaaaaaa atttattaca gatatataca
     1081 ataacttacc tacagatagt gatgagtttt tggaaaaaga ggagaaagta gaagaattag
     1141 ctgactggat ttcaaaatat attcaaaata aaggatatag agcgtattct caatcggaga
     1201 aaaacaatct agaacatgga tattttgaaa aagcctatat taatccagaa atgcaatcag
     1261 ggattagtcc tttaccacat aagacaatag caaatattag tggcattgga tttatgggaa
     1321 aaaataattt gtttgtaaca gaggaatacg gatgtgcttt tagcatgtgt acagtactta
     1381 cagatgctcc aatttctgtt gaaagatatc ctttgattga ttcaaaatgt ttaaattgta
     1441 atgtttgtgt agagaactgt cctgcaaaag ctatacatgg aaatgaatgg actttacctg
     1501 gaaaaagaga atctattatt gatgtttcaa agtgtttttg tgcattgagg tgtatgatga
     1561 gttgcccatg gtcattaaga tatgcaaatc aaaaataact ttactagaga aggtattaaa
     1621 ttgaatatta taaaattttt aaaatgtaag attatataag atttctcaaa ataaaaattt
     1681 gtatagaaca ctcagaaatg agtgtttttc tattgggatt aaattatatt gatacaaagc
     1741 ttaactattt taatcattat ataaaatttg tattaaaaaa ttaagaataa cttgctaata
     1801 gtaaaaatat aatgagatta taattgattt ataatataac tgtaatgatg ttgtaaaatg
     1861 aaaattgtca tctcaaaatt cccaaaaaga gtaaaagtca cttcggttat agtcaaaaaa
     1921 ttttttctgt gaaaagaatt tagatttaaa agggaggaat taatcatgga aattgaaact
     1981 aaaactccag attggattaa tgtactagaa ttaaacagta aaatagatat tacttggaaa
     2041 tatgatgtaa gtaatatgat acaagatatt gtctctgata agtcactaga aggttccatt
     2101 atatattttc caaaaggtaa ttacttattt gagaaaggta ttaaaattag tcaacaaata
     2161 acacttcaag gagattctta ttatggagga gataatcaag tatcaaattt agataaaaaa
     2221 caatcaatcg taggaacaac caattttata acccgaggag tttctaatat aagtattatt
     2281 acattggaag gaacaagtca atgtatcaaa aatattaatt tttattatga tagtcatgat
     2341 atagagaaaa taccacctaa aaatgtatct gctattacag aatatggaga aacacaagga
     2401 ctatttcact ttgaacacct gtttatttct ggattttcag gaatagggat tgaaattcca
     2461 tactattcaa ctggcaatga tatcattgtt agttcatgtg gtcttggtat gaggcttgga
     2521 gagaagtcaa tgctttctag tagcaagatt tatgaatgta aaaatggaat ggagattact
     2581 actggtgtta gcttaaataa tgtgagaata gaagaaataa gagaaatagg tattaataat
     2641 aaaggatttg gttttaacct gattatgaat cttatggtcg accaatgtgg atattgtgga
     2701 tttatgtttg aaaaaatgtg ttatagccag ataactgcca gaattactaa atgcggtcag
     2761 tattataaaa gtgttgatta taatacttat gagaatatgg aagatagaaa agaagaagct
     2821 tattccattt tttatggaga tattttagaa aattgcaata ttgtattgat gaatagtaat
     2881 attgatacct tagaaaatga ttcacttgat gaacataaga tatatgtaat caaggcaaat
     2941 gaaacaaaca aagtaatgtt aacatgttat gctgaagcag atgagcttat acagtgcgca
     3001 aagggcaact tgttgctaga aaatggtgaa aatacttata aattttataa tggtgagatt
     3061 tgttctgtag gaggtgttca aatttctgat atagatgaaa aagatttaat caaaataatc
     3121 gagaacactc tgtatataga tgataaaggt aagtacttaa tggttcctag attaaaaaag
     3181 aatactgtaa tatattcagt actagattct atagaagaaa taaataaatt acatggtgga
     3241 atatgggaac agattgatgt aaaagtatta gctggggaat ctatgtacta ttataaaaag
     3301 ataaaagatt aaattatcaa actaggaggt agtgattaat ggaagagtct ataataatta
     3361 aagatataag tggctggatt aatgtacttg attatgggat ttgtaatgat gaaacaaaag
     3421 atgtaagttc caagttgcaa gagattatag atgctgcacc agaagattct attatatatt
     3481 ttccaaaagg aaaatactta tttgaaagtg gtgttaagat taagaaacga ttaaccttat
     3541 gtggagattc ttatattttg gcgaatgttc ctaaaaacac tgctggagta acacaattta
     3601 cttttaaagg aaagaaaaat cctaaaagtg aaaatatagc aattataaca gcaaaaagtg
     3661 taagacactg tattaagagc atttgctttt attcagatag ttgtgataga gatatgacat
     3721 ctaatcatga acctccaaca gatggaaaac ctagatttca tcataatgta attataaatt
     3781 atagaaatat atcggctatt gtatgtgaag ataaacaggg agaaccaggt cattatgaaa
     3841 acttgttttt tagtggtttt tctggaattg cacttgatat gcctaataat tctacagcaa
     3901 atgatattac agtttttaca tccggacttg gaattagtac aggggaaaat tcaacgattg
     3961 ctaacagtaa ggtttggggc tgtgttgatg gaatgataat ttctactgga acttttataa
     4021 atggtatgag ggtagaagaa ataaaaaaag ttggaattaa aaatattggt agaggtttaa
     4081 attttattac aaatatcaca attgaccaat gtggatattg tggagtttgg tttgattcta
     4141 tatccaatgt tcagatatca ggaaatatca caaggtgcgg acagtactat tatgatgtaa
     4201 gctatgataa ttatttaatg ttggataata gagttaaaga agcatattct ttattctatg
     4261 gtaatttatt ggagtcaagt aatatagttt tgtcaaatac caataaagat aattgggaag
     4321 atttcaaaga ggataagcat aaggtgtatc ttgtagaagc acttgaaacc aagaatgtac
     4381 tattaacatg caatatagat gctactgact ggattgttaa gtcagaaaaa ggaaatttaa
     4441 cgtacaataa tatgcgacaa actgttatat tttacgatgg aaaactaagt agtatcaatg
     4501 gaattggtat atctgatgaa gattatgggg ataaagtcaa gataaaaaaa ggaaatatat
     4561 atataaatag taaggataag gttattaaga tgcataaacc agaggtaggt gacattatgt
     4621 caacaattat taaagatgaa aatatacttt ccgctcatta tgggggaaca tgggggaaaa
     4681 ttggtgaaaa aatagagttt ggaataactg tacactatta taaattgata gagaaataag
     4741 taaatacgta gtatttgaat agatgtattt tattggagag ctaggactat agttttaatg
     4801 taaatggttt ggtaatagca tggattgaat aatataaaaa taatataaaa aattaatttg
     4861 attatgtaaa attctatgaa gtagtaaacc tgtgacttta gtcatggtag gttcaaatta
     4921 agtaaatggg aaaggaatat ataatattat ggaaggaaga actgggatta aagatggaag
     4981 atggattaat gtagtagaaa gaggtattaa aaatgatggt tcgtacaaca taggtcctga
     5041 tttacaggat attattgatg aaatagaaac agatttctgt gtcttatatt ttccaaaagg
     5101 aaaatactta tttacaagtg gtgttaaaat taataaagaa attgtattac aaggtgattc
     5161 taattcacct acagagacta cacaatttat aactcgtgga gtagaaaata tgagtattat
     5221 tacattgaca gggaagaaac aatgtattaa aaatataaat ttctattctg atagttgtga
     5281 gatacaggta aatgaagaac caccgacaaa aggtaatcct aaatatcatt atgagatgat
     5341 tattaataag aatgaaaaaa atgttgagat gaataatgta tcagcaattc tgtatgataa
     5401 tagtaagaat atgattaaag gtctaggtca ttatgaaaat atttatataa gtggtttttc
     5461 gggtacagga attaggatac catattactc aattgtaaat gatattacag tttcatcttg
     5521 tgggttgggt attgatacag gaatagacac aattatttct aatagtagaa tatctaagtg
     5581 tcaaaatgga atgaggatta gaactggaac tagcataaat aatgtaagaa ttgaaaaaat
     5641 acagaaagtt ggtcttataa gtagtcaagt taaggattat gagggatatg gaagttataa
     5701 aattaataat attacgattg accaatgtgg gtattgtggt tttttatttg actcagtgaa
     5761 aggtagttat ttttctggta ttataagaag atgtgggcag tattattata atacagatta
     5821 tgacacatat ttaagtatta aagatagagt agaagaagca tattctttat tttatggaaa
     5881 ttattttaca gaatgtaata ttgatttagt tagtgataat aaggataact gggatgatgg
     5941 cttagaatat aaacataaag tttatgtatt taaaaccctt caaataccaa aattaacatt
     6001 gagatgcaat atagatgcct atgattatat cgttaaatcg gtacatggag gaggtaattt
     6061 aatgttaaaa aataacttta acaattatat atttattgat tcatctagtc cagaagttat
     6121 taatggaatt aattttaatt atcaaaagaa tggaaacctg ttaaggttaa ataatggtaa
     6181 attaagttat aaaaatggaa aggaagaaac agctatattc agacctaatt atggtcttat
     6241 tgtagcatca acagattcag aatgtgaaca aatagagact agctatggag gaaaatggga
     6301 gaagcttggt tctgaagtaa ttggaaaaga aacggtatat tattataaac atcatgaacc
     6361 agataaaaca aaccaaataa aataaaattt gtattatata atgatataaa gttttaatat
     6421 atagtgttta cctttaatgt aatattggta tatttgtata gtattaaatt tgttaaaaag
     6481 taaaattgta gggtgcttga aaatagcacc ttttttagtt tcattataaa attagttttg
     6541 aaagtttagg aataatgtat atttattttt aaagaattat aaccttatta aggatatttt
     6601 aaatgctaga aatgaatcag taaatcatac tggaattatc ttaaatgttt tgattaaatt
     6661 aagtatttag agctataatt atattaaaaa tatattagga cataattata ttactatgga
     6721 ggttaaatat gatagtaagt gtgagtagaa gaactgatat acctgctttc tatagtaagt
     6781 ggttttttaa cagacttaaa gaaggttttg tttatgtaat taatccaatg aatccaaaac
     6841 aggttagtaa gatagagtta aatccacata ctgttgattg ttttgtattt tggacaaagg
     6901 atgtaactcc aatgttatat gatttaaata aattaaaaga ctataaatat tattttcact
     6961 atactataac atcatatgga aaagaagtag agacatgtat tttagataaa agaaaggtaa
     7021 tagattcatt taaggaattg tctagaaaaa taggcaaaga aagagtaatt ttaagatacg
     7081 acccgatttt cttaagtgaa aagtacacag tagattatca tatcaaagca tttgcgagtt
     7141 tatgtaatca gcttgatgga tttacagaaa aatgtataat aagttttatc gatttatata
     7201 agaaaacaaa atttaatact aaagcattac atataaagcc aatagaaatt acagaaatag
     7261 aaacattatc aaaagaaatt tctaagattg ctcataagca tgggataata cttgaaatgt
     7321 gttctgaaga atataattta agtaaatttg ggattggaaa aagtaagtgt attgatgata
     7381 gattaatatc aaaaattata ggatgtgaag tagaggtaaa aaaagatagt acacaaagag
     7441 atatttgtgg atgtgttaaa agtgtcgata taggacaata caatacttgc agacattatt
     7501 gtctgtattg ttatgctaac tttaattatg caaaagtaga agaaaactgt aggctttata
     7561 aagaagataa taaattactc atagatactt taagagatga tgcaaaaata agcattagag
     7621 atatgaagac tattaaagta gataagaata aacaaattag tatatttgat taaaataaat
     7681 atactaatta ccttaatata tcaagaatat agatactttt gataacaaaa ttaaacttaa
     7741 tagatatttt ctatataaga aagatggtca taatatgtca atttgaccat ctttttgata
     7801 taattaaaac acaaataatt tagtaacaaa ggaggcagaa cttgaattta ttaaaaaaat
     7861 atcctatacc tattgcaagt ttgattttgt caatttttac tttaggtaac ttattacaat
     7921 cttatagtga atcattacgt aatgtaattg gatttatagg atttattttg tatgcaattt
     7981 atatagtcaa aataatatta cttagaaagg gtgttaaaga gcaattagag aaccctttaa
     8041 tatcaagtac atttccaact ataacaatgg caacaatgat atttgctaca tatataaaac
     8101 cattatcttt agaattaagt attatgattt ggagcatagg aattgtgggt catcttgtgt
     8161 taatagtttt atttagtaag aagttcttag ttaaattctc aataaaaacg gtatttccat
     8221 cttggtatat agtatatgtt gggatagttg cagctagtgt tacggcacca gcatttaatc
     8281 aacttttgat tggcaaaatt gctttttgga taggatttgt atcttatata gttcttatac
     8341 cagtaatttt aaagagagta tggataatca aggaaatgcc tgaaccatct ttaccaagta
     8401 tagctatatt agctgcacca gggtcactat tattgtctgg atatattaat tctttttcag
     8461 ataaaaataa tgtagtatta tacttgttat tcatattatc aattgtattt tatattatag
     8521 ttttgggata cttaccgaaa ttattaagat tgccttttta tccgagtttt gctgcattta
     8581 cattccctat ggcaataagt gcaatgggta tgaaactaat gaatggttat ttaactaaat
     8641 caggtcattt tataagttgg atttcatatg cttctaagtt agaagagata attgctacag
     8701 tgattatttt atatgtttta gttttattta ttatatatct tagtaaatct gaaactacat
     8761 ctaaagctaa ataagaatta ttaaatatgt gtatttaata ggaatattga tataaatata
     8821 tgaagataag ataaaccata gaaacttaat ttagcttaat tttattggag gaaaacaaat
     8881 gaaaacaaaa gaagaatatt taaaagaagt tagaaacata tcagaagaat actttagaaa
     8941 aggagagttt ttttgctctg aagcagttct tcagacaata aatgatgctt taggccaacc
     9001 tttaagtcca gagataacta aattagcatc aggatttccg ataggacttg gaaaagctca
     9061 atgcctttgt ggagcgatat ctggaggaga gatggcttta ggtatagtat atggaagagt
     9121 acatggagaa actatgaatc caaagatgtt tgagcatgct aaaggtttgc atgattatat
     9181 taaaaaagag tatggtgcaa catgttgtag agctattaca aagaaatggg atggtgataa
     9241 ctttatgtct cccgaaagaa aagagcactg tattaaaata acaggtcaag ttacagagtg
     9301 ggttgcagat aagcttatag aagatgaaaa acttaatatc aaatagtgta atattagttg
     9361 gtgaatttat aaagttaaat ttacttatag tataagatac ttgatattct cgtattgata
     9421 gaaaaattta tagcatatgt atttaatgaa atatacttat atttagagtg tggtttaatt
     9481 tcataaatac atatgctatt attttaagta tataagcaaa tttatttaaa taaatagaaa
     9541 cagttaattt atatgtacaa aactatatat gattagtgta aataaatacc tattttataa
     9601 tactcaacat aaagacacca gacatgatta gtattatacc aataaaaata gcaagccatt
     9661 cttttttgtt cttcttttct ttaaaaaata taatccctcc taaagtggct actatcacac
     9721 aactctgaga gatagaaaaa cttattgtaa ctcccaatgt attagtcgtt atgaacatac
     9781 ctaaatttgc tattgaccac aatataccag taattaaatt gaataaaaca ttttccctat
     9841 atacaatctc tttagaaaaa tacttgacaa taatagatga agttatcaac ataccaacag
     9901 attgaggtaa tataattcta tatccttcaa ttaaaaatat ttgattagtt acaacatata
     9961 atgataaaaa tagagatgat aataatacaa ctccaacaca ttttaacata tttttatctg
    10021 tagatttttt agtttgataa ttagtgagaa gtataccaag tattatacat aatattgata
    10081 aagaaccaat cagtaacatt ttagaactgg tccattcatt aaacaagatt acagctaata
    10141 atgtcgtaaa agttaattgt gaaccatttg aaattggcat tactttagat acactagcaa
    10201 tttgaattgc tttaaactgc attaattgtc ccaaactcca gaatatgcca gaaatcatac
    10261 ttatacaaaa tgaaaaaaat gtaatttcag gatgtataac cagagttatt atagtggaaa
    10321 atataaacgc acttatggat gtacctaaaa gctgttcatg aggagaactt ttctttagat
    10381 ttgcaactat gggcatcaat ccccatccca ttacaggaag taaagcaata attattgtca
    10441 gcattaaact atttcctttc atattaaatt tagacagctt ttaatttatc atctaaaatt
    10501 aaagtgttca atacataaaa attaccgtat ttaatcagga aatattagta gttttttaga
    10561 aaaacatttt ccattaaaat aaagataaag ggaaggagta aaattgaaaa tgttaactga
    10621 tatgattcaa aatcgtgaaa ttaaaataat aaagttttta ttaaaagaag gtcatacaac
    10681 tgtaaaagca atagcagatg atttagatgt ttcagaaaaa acagtttcaa aatctcttaa
    10741 agaagtagaa gcagtgctta aaaagatagg tctttcttta ataagaaaac ctaagatagg
    10801 tgtttatatt gatggagatt taaaaaaaat acttccttac ctagataata aaggaagtca
    10861 aattcctaca accagagagg agagagttat ctatatatat tcagtacttt taaagagtaa
    10921 tgattatatt actatacaac aactttctga tgaactatat ataagtcgtg gaactattga
    10981 aagggattta tcagaagttg aaaaactgct aaaaaacgaa gggatttcca tatataagaa
    11041 acctagtaag ggaataaagt taaatataag tgaaagagat aaaagacaac ttactgctaa
    11101 gtttatacat aaattttgga gtagaaactg gtatattaag caagagcaag aaagctttta
    11161 tcaagcattt gaaaagatac aggcagatgt aaatggtatt ttttcggaag atgatttatc
    11221 aataattatt gatattctta ggaatttcag cagagaaaga aaatttgagt tctctgatta
    11281 tgaatttcag tcattagtta ttcatttggc aatagctgta gagagaatta gaaaaggcga
    11341 atatatagaa gaaagtttgt atattggtaa tatagaaaat aatcaaatgt caaataccaa
    11401 ttatttagca aaacaattag aagaaaaatt ttcaatatta ttaccaaaat ctgaaattgg
    11461 atatataaat ttacatttag tagcggctga ccaacataga gatactaatg aactaaaaaa
    11521 tacttcaact aatccttgtg aaacaagtac aaataatata tcaaatcttc gggaaattat
    11581 aaaaaataca ttgtatgaga cagcttatga caaggattta attgatggat tgacttcaca
    11641 tgtacattca tcaataaata gactgaaata tggacttagt attaaaaacc catatgtaaa
    11701 tacaatcaaa caaaactttt ctttatcatt tgagcaagct ttagatttaa agaaagtaat
    11761 tgaatttata tatgatatta gaataaatga tgatgaatgt gcttatatag cattacattt
    11821 tgaagctttt agagaaagaa tgaaagaact tccacaaaat attagagtaa ttctagtatg
    11881 cagtacagga ttaggttcat ctaggttatt gtctgcaaga ataaaaaaat actttccaat
    11941 gataaagatt gaaaaagtac tttccgtaca agaattagta tccagtaaaa ttgatgcaga
    12001 tttagtaata agtactattt atttagagtt agaaacaatt ccaaccatag tagttagccc
    12061 tattttaaat gaaagtgata taagaacctt ggaaagaaat atacaaaatg tttcatgttg
    12121 tacttctaag aagtataaat ctttcagaaa cctaatcttt gaagaaaata tattgttaaa
    12181 tattgaagct tcaaactatg aagatgcaat taagtatata acagataacc taataaaaaa
    12241 aggttttgta aaagaaggta tagctaaaag tgcaattgag agagaaaatt tatcttacac
    12301 gtcttttcag tcaatagcta cacctcatgc taatcctagt tatattaaaa aatctaatat
    12361 atctgttgca acgttaaaaa atcctattac atggggaaat gaaaaggtgg aagttatttt
    12421 ctttatttca ttagaaaatg acaaaaacct agagcttgat gaaatatatg aagtttttta
    12481 tgactttatt gacaataaaa aaaatataaa tgacatatta agtgcaactt ccacaaagga
    12541 agtgtacgat ttgctattgg aggagagtat atagtgaaaa tatcagatgt attgaaaaaa
    12601 gagcaaattg tttttaatct tgatacaaat acaaaggaag aaacaataaa aaaattaagt
    12661 agtatatttg ttgaaaatgg gattgtggac aatgaagaag aatatgttaa gtctgttttg
    12721 gaaagagaag aacattcaac tacaggtatt ggtaatggta ttgctattcc tcatggaaaa
    12781 agtgatgctg tcaaaaaatc ttctataata tttgcaaaga ctaagcataa gattgagtgg
    12841 gatgctttag atgaaaaacc agtagatagt attttcttat tggctataag caatattgat
    12901 aaggatagca atcatcttgt actattatct aaattagcaa ctaaacttat ggatgatgac
    12961 aatgtagatg cactaaaatt agccaattca gaacaagaaa taatcaatat atttagtgaa
    13021 gaaggagaga tgtagaaatg aaaagaaaaa ttatagcagt tacagcatgt gcaacaggag
    13081 ttgcacatac atatatggca gctcaagcgt taaagaaagc ttcaaaaaag atgggtcacc
    13141 ttataaaagt tgaaacacaa ggagctacag gaatcgataa tgagttaact acaaaggatg
    13201 cacaaattgc agaagtagta atatttgcag tagatactaa agtcagaaat gctgaacgtt
    13261 ttgagggaaa agaaatacta gaagtaccag ttaatgcacc tataaaggat gcagagaaag
    13321 taataaatga tgcattaaag ttaattgaca ctaaataaat ggagggaaat gtaatgttga
    13381 aaaagatagt ctctgagtta aaaaagcatg tcttaactgg aatctcatat atgattccat
    13441 tagtaattgc aggtgctatg ataatggcaa tatctcgtgt aggtggttct ttctataata
    13501 taccagatat atgggatgct aaatacgcag aaagtgctag tagtattgtt agattattac
    13561 atgatctaga tggatttgga ggtactgcat taggattaat gtttcctgta attgctgcat
    13621 ttataggatt ttctatagct gataaattag ctattgtacc aggtcttgtt ggaggtatga
    13681 ttgctaaaga tataggtgca ggatttttag gagctttggc agttggtctt atagcaggat
    13741 atacatgttt gtttattaaa aatcatgtta aattaccaaa atcagcagct tcaatagtac
    13801 caatatttat agtaccagta tttggaacat taatcactgt tgtattaatc aattatgtga
    13861 taggtatacc ttttgccaca ttaaatactg gattagaaaa ttggttaaat ggattatctg
    13921 gtacaaatca gatattaatg gcagctatta taggggctat gatggcagtt gacttaggtg
    13981 gaccagttaa taaagcagct ttaacaacat cacttgcatt attaacaagt ggaatttatg
    14041 cacctaatac tgctgcaatg gtaggaatag ttataccacc actaggattg ggacttgcta
    14101 ctatactagc aaaacaaaaa tataataaac agttacgtga agctgggaaa tcatctctta
    14161 taatgggttt aattggagta agtgaaggag caattccttt tgcggtagaa tctccattaa
    14221 aagtaatacc ttcatgtgta attggaacag caattgcttc agctatggca gttggtttag
    14281 gttcagtaaa tgcaactcca attagtggat tttatggatg gtttacagta gagaattggc
    14341 caatgtatgt gttatcaata gcagttggaa cagtaattgt agctggatta gttatagtat
    14401 tgcgtggaaa tccagtgatt gaggatgatg aatttgaaga tgatgatttt gatgaagcag
    14461 agtgggaatc ttaaaattta ataactattt aagacgtgtt ataagctata ttcaatatga
    14521 atcttatact aaataaagtg ttaaatattc agtttagact taaatataaa agataaagaa
    14581 cagaggagaa taaatgataa aagcacatat tgttaatcat acacactggg atagagaatg
    14641 gtattttact tctggagatg cattagtact tagtgaacaa ctatttacag atgtaattga
    14701 tgaattagaa cgtaatccag atgtaagttt tgtacttgat ggacaacttt ctattttgga
    14761 tgattatgta caattacaca aagaaaaaat agaaatcatt aaaaagttaa taaaagaaga
    14821 tagactacat attggaccat ggtttactca aactgatgca ttctttgcta gaggagagtc
    14881 tattttaaga aacttaatga ttggaatttt tgaaagtaaa aagtatggta agtatatgaa
    14941 aattgggtat ttgccagata catttggatt taatgcacag atgcctatac tattaaagca
    15001 tgtaggtctt gataatatat tcttttggag aggtatacat cttggtaaac atgttcaatc
    15061 accatatttt aagtggaaaa gcttaaatgg agaaagttat atatatgcag taaatatgcc
    15121 acatggatat ggaactggta tgcttttaga gccttcatta aagtatgtta atggacgctt
    15181 agacccagct attgatttta ttaaatcata tactgatgta gatgaggtgt taataccttc
    15241 tgggaatgac cagttaaata taataggtga tttcaaaaat aaaattaaag cgattaatga
    15301 tatcggaaag tattcatata taacgagttc atatcaagag tttttaaaat atataaagtc
    15361 catagaatca ctagaaagct atagaggtga atttagagaa cctgtattag caagaataca
    15421 taaatcaatt ggttctagta gaatggatat aaaattagca tgtgataaac tagaaaacaa
    15481 gctgattaaa agaatagagc cattattagt aattgctaaa aagagtaaaa ttgaaataag
    15541 caatcagtta cttataaata catggaaaaa acttttggaa ggacaagcac acgatagtct
    15601 agctggatgt gtaactgata ctgtaacaga ttatattctt caccgtataa gagaagcaaa
    15661 tgaaatatgt gacagtattg aaaatactat tgtaaaaaag atttcagaag ggcttaaatt
    15721 atctaaaaat gatattttag tatttaatac agaagctaag cgttttaatg gatataaaga
    15781 gatacaagtt gtaagtgata gtaaaaatat ttattttaaa gataatttag atgctactat
    15841 aattgaagaa acttatgtaa aaccgagaga aaatgtatta gaagaaacac ctgctggcaa
    15901 cgtatttatt gaagaatcag gatattatat attaaaagta agaataaatg tacagcttcc
    15961 tgcacttggt tataaagttg ttagttttga atcaagtgat aaagaaatgg tatcacttga
    16021 taaatctaat gacactttta tatctaatga taattataag ataatctatg aagatggaag
    16081 cttaaattta caacttaaag atggaactta catatcaaac tttttaatat taaaagatag
    16141 tggtaatgca ggcgatacct atgacttttc tccattaaaa aatgacgagg atataaaact
    16201 ttcatttgat agagtgtata cagaaaaaac tttaggatat gaaaagttgg tggttaaagg
    16261 tactacttta ctaccactta cattagaaga tagaaaaaac aaatatctta atgggaaatt
    16321 aaatgtaaaa gtaagtattg tcttatccaa agaaaatcca ttgatggatg taaaactttg
    16381 tgttgataac acgatatata atcatagact acgtgttcat ataaaaactg atataaaaga
    16441 taataaaaac atagcatcat tgccatttgg atatataaca agagaaaatg gagttttaga
    16501 caactgggaa gatatttaca gtgaaatgcc tatagattta gaacctttgg aaagtaatat
    16561 tactctaaca aaccaaaata gaagctgtac tgtatttact agaggaataa aagagtatca
    16621 acatattgaa gatgaaattg cattgacctt acttgctact acagatgaac taggaaagcc
    16681 tgatttatta tatagaccag gacgtgcttc tggtgataca actaaaaaag gtcatataag
    16741 aattaaaaca gataaagctc aaatgcttaa gaaattagaa ttttcatttg caatatatat
    16801 ggattctaaa tcatttgatg aattggaaat tgcgaattta acccacaatt atctaaggga
    16861 atgtgtaaat tatcaattac aggattacaa tttcttttta tatcgtatag ataataagat
    16921 tcaaaaatca attgtcaata aaactgtaag tagagaatta gaaataatat ctttaccaga
    16981 aaaatatctt atatcagcat gttatccttc ttattacagt aaagataaat ttataataag
    17041 agtggaaaat ccaagtagta atagaatgat attggatgag caaatattta aaaatagaaa
    17101 tgggaaaatt gtaaatgcaa tagaagatgt agaagaagaa caggtatatg aaatagcacc
    17161 ttttgacgtt atttcaatat tattggattt ataagtgtaa aagtaagttt attgtttaaa
    17221 gtctgacaga tattaatctg ccagactttt taatttgtat aaatttgggt aaatattaat
    17281 gaatagtttt agtatttaaa tatgaattta gtatttaata tagaatttat tgaagtagaa
    17341 taattagttt aacaggataa gcagtttaaa ta
//
LOCUS       DAMJWO010000087        17138 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.089, whole genome shotgun sequence.
ACCESSION   DAMJWO010000087 DAMJWO010000000
VERSION     DAMJWO010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17138
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.089"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(214..738)
                     /locus_tag="PC366_003047"
     CDS             complement(214..738)
                     /locus_tag="PC366_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2578543.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQIMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(803..1555)
                     /locus_tag="PC366_003048"
     CDS             complement(803..1555)
                     /locus_tag="PC366_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF2578544.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDISKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(1586..2884)
                     /locus_tag="PC366_003049"
     CDS             complement(1586..2884)
                     /locus_tag="PC366_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HDF2578545.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEDIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMEDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQQGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREVNVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(2901..5165)
                     /locus_tag="PC366_003050"
     CDS             complement(2901..5165)
                     /locus_tag="PC366_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HDF2578546.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(5420..6238)
                     /locus_tag="PC366_003051"
     CDS             complement(5420..6238)
                     /locus_tag="PC366_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF2578547.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGIDEKIIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIIL
                     LDEPTAGLDPVSTRSIVDIIKGLNKDNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFVNENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(6231..6929)
                     /gene="cbiQ"
                     /locus_tag="PC366_003052"
     CDS             complement(6231..6929)
                     /gene="cbiQ"
                     /locus_tag="PC366_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HDF2578548.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIKNIFVLSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEIFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKMHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(6932..7216)
                     /locus_tag="PC366_003053"
     CDS             complement(6932..7216)
                     /locus_tag="PC366_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2578549.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPDYEPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGVQKGKRS"
     gene            complement(7206..7958)
                     /locus_tag="PC366_003054"
     CDS             complement(7206..7958)
                     /locus_tag="PC366_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HDF2578550.1"
                     /translation="MKQNIKLGVIAALMLIVLTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLVGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIISFLIFKALKKKDG
                     NNAMPVFLAAAIGDLATYTVTSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(8147..8339)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(8471..10243)
                     /locus_tag="PC366_003055"
     CDS             complement(8471..10243)
                     /locus_tag="PC366_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HDF2578551.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYNMDKHPALDSMTRRIVNDIRNIDTN
                     QDMMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(10257..11186)
                     /locus_tag="PC366_003056"
     CDS             complement(10257..11186)
                     /locus_tag="PC366_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2578552.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            11415..11603
                     /locus_tag="PC366_003057"
     CDS             11415..11603
                     /locus_tag="PC366_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2578553.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRAKRRKEVQYE"
     gene            11596..12297
                     /locus_tag="PC366_003058"
     CDS             11596..12297
                     /locus_tag="PC366_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2578554.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHCGAEGLHLLDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSINNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            12299..13222
                     /locus_tag="PC366_003059"
     CDS             12299..13222
                     /locus_tag="PC366_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2578555.1"
                     /translation="MNTSVYLLLILALSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            13379..14302
                     /locus_tag="PC366_003060"
     CDS             13379..14302
                     /locus_tag="PC366_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578556.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGCEKRVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDHTLRLYNTTLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            14295..15032
                     /locus_tag="PC366_003061"
     CDS             14295..15032
                     /locus_tag="PC366_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2578557.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPTKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFASIALGRRK"
     gene            15043..15816
                     /locus_tag="PC366_003062"
     CDS             15043..15816
                     /locus_tag="PC366_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2578558.1"
                     /translation="MWKLLWAECQKIRRSKIVWITFFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETKLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            15832..15984
                     /locus_tag="PC366_003063"
     CDS             15832..15984
                     /locus_tag="PC366_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578559.1"
                     /translation="MKKIKKLIILIVFLFLFGMLHCYTEWKFNNDPPKGVIERINEWT
                     DKIGLD"
     gene            complement(16357..16965)
                     /locus_tag="PC366_003064"
     CDS             complement(16357..16965)
                     /locus_tag="PC366_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDF2578560.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
BASE COUNT         5524 a         2979 c         2150 g         6485 t
ORIGIN      
        1 aaataaatat ataaacaatc ataataaaat ttttttaata aaactttatt ttttagttaa
       61 aatcatacaa tatatagctt tccacaatac aaataaatta aaaagtgaaa tgtatttgtc
      121 taaaaacata ataacatttc actttatcct catttttaag taatatatat ttttaatttt
      181 tatttataac tcaatctagt ttttatataa gttttagttt ttttctacat ctgagtaatc
      241 tattccaaaa gtttctacag taacagactt cataatttgt ggagtttgtg gcttatcagc
      301 tgaatctgtt ctaactgatg ctatttcatc aactgtatcc ataccttcta tcactctacc
      361 aaaacctgca tactgaccat ctaagtgtgg tgagttttta tgcattatga aaaattgaga
      421 accagctgaa ttaggtgcca tagttctagc cattgatatg actcctcttt catgttttaa
      481 attgttagta aatccattac cactaaattc accttttatt gagtgacctg ggccacccat
      541 tcctgtacca tttgggcatc ctccttgtat cataaatcct ggtattactc tatgaaatat
      601 tattccattg taatatcctt catttactaa tgatacaaag tttttaactg tatttggagc
      661 tatatttgga tataactcaa ttttgatttc ttttccattt tccatttcta tagttactat
      721 aggattttta ttttccataa tttattacct tccttttcat tagttaaatt acataattac
      781 atttattata ttatactcta aattaaagtc tatcaagtat attttttcct atttcgtatc
      841 cttcttgata aatagtttta caaaactcat catcaaagtt aagcgtatct ttaggagcaa
      901 attgagtatt aggtctaact actattattt tatcttcatc atatactttt ttaatatcct
      961 ctggcaactc ataattatat tttgtggata ttaaaataat tttatccaca ttatccccaa
     1021 ttaatggttc aattaatgca ctcctaatta aacctccatc taatttgaaa ccatcataaa
     1081 ttccttcttg cacatctttc acaaattgtt ctttaaatcc aagagttgcg tttggatttg
     1141 atggtaacaa cccactgtat gaaatgctga taatggcttc attacgaggc atttttgata
     1201 tgtcaacaat cttttctgat actactttat tatcaacttc aacataatta acataaaagt
     1261 tcatttcttc tatattacta tcatctagtt cccttaggtt gtctatagca ggagaattat
     1321 ccacagtatt atttactatt tttacatttc cattctggat atcttttata tttgtccaca
     1381 ttttctccaa gttatcaaca ttccctgtgt acaaataata tccatttatt gctcctattg
     1441 atgtccctga aatcgaataa aatttattta ttcctccatc atacaaggct ttaactactc
     1501 ctgcttgata agcccctttt gctcctccac cttctaaaca taatcctaat ttcatagtct
     1561 catctccaaa ttgtttatct tatatttata tttcaaaaaa cttactaaat gttttatata
     1621 tactatagtg gtcctcaaca tttcctaatt ctcttataga gtgcattgct aaaattggac
     1681 ttcccacatc cacagatggt atatctatat gagtagaaga tattggacct atagtacttc
     1741 ctcctctttc atctgaccta ttaacaaatt cttgatactc aacattaact tctctacata
     1801 tatttttata aatagctata gaatatccat cactagtata tgcctgacta gcatttatct
     1861 ttataactgg accttttccc attattggtt tattagttgg gtcatgcttt tctggaatgt
     1921 ttggatgaat agcatgagct aaatctgatg atatcataaa agatgaataa atagactcaa
     1981 agaatccctc tctatcctta cccattgata tgcaaattct ctccaatata tttaacaaca
     2041 tgtttgaatc tgcaccttgt ttagtagagc taccaacttc ttcattgtca aatacagcca
     2101 ttacatttac accttgttga cctttagtat taacaagagc attcaaacta gcatgtacca
     2161 ttgcaagatt atcttgtctc ccaatagata taaattcatc attagcccct attaaacttc
     2221 ctttttcaaa ttcatataaa aataaatcaa aatctataat atcttccata tttacatcta
     2281 agttagatgc tatttgcttt ataagaaaat tatctttttc taatgtatca tttaacatcc
     2341 caactaaagg taacatatct ttttgcttat tatatgaatg accatcattt atacttctat
     2401 ttaaatgtat tgctagattt ggtattatac aaattggctt tttaaagtct ataagccttt
     2461 catttggttt taatatacta tcacctttta aaactactct accagctatc ccaagaggtc
     2521 tatccaacca tgtacttaat attgctcctc catagcattc tgtatttaac ttcaaataag
     2581 atttttcagc ttctatttct gcatttggtt taatactaaa tgtaggagaa tctgaatgag
     2641 agcctattat tctaaatcca tctctttcta tatcttctga atttactaca aaagctacta
     2701 tagctgatag attcttagta acataatact ttccaccaac tcttagattc catctttgat
     2761 tcaaaactaa ttcttcaaat ccatttttat ctaagatttc cttagtactc tcgactgcat
     2821 gaaaagacga cggactatca tatatgaagt ctattaagtt tttagcaaag tttatactat
     2881 ccattcctca tttacctcca ttataaaata tttagtgttg tatattcttt atttattttt
     2941 ttaattccct gttggtcaaa agctatagta acatctgtac caattataga aaccactgtc
     3001 ccaaccccaa atttaggatg atgtacctta gaaccaagtt ttatatcatc tggattagtt
     3061 tctttattag aatcttttat tgtagcatta actttatctg caactttaga tttgcttata
     3121 gtactcatat actttttagt atatttatct aacatattat aacttgcttt agaatagctt
     3181 agttcttttt ttactttgta caatctttct atacattctt ctggcagttc ttccataaat
     3241 cttgaagcta ttgcaacatt tgttttacca tataatgttc tcttctctgt caatgacata
     3301 tatagctctt ctttagctct agttatacca acataacaaa gtcttctctc ttcttctatt
     3361 tgtgaatcac tcatagattt tatagctctt gatataggaa ataacccttc ttccatacct
     3421 gttaaaaaca caacagggaa ctctaaacct ttggatgtat gaattgtcat aagcgaaacc
     3481 ctatcattgt cttcttcatc atttgattca gatgtaagtg ctatacttgt taggaatgtc
     3541 tctaagtctt tattttcata agtatcatca ttactacttt caaactccaa agctatagaa
     3601 ataaattctc tcaaattatc aattctgtct tgagcttctt cacctttgcc tgttaaatct
     3661 ttttcatttt tatttcttat ctctacaagc tcgtccatat atcctgtagt atccaagact
     3721 ttttctataa gtttgctaac aggataaact tcttttatag ttctaagagt ccctataata
     3781 tcaacaaatc cacttatact tgcccttgcc ttagtagata tatctgaatt tgtttctata
     3841 tcaattaata ctgagtatat actttcctgt tttaagttag ctctatcttc aattttttct
     3901 atagttctaa gccctatacc tcttctagga acatttataa tcctttttat agatatatca
     3961 tcttgtggat tttgaataac tcttaaatac gccaacaaat cctttatttc ttttctctcg
     4021 tagaattttg taccaccata tatattgtat ggaatttgac ttctatttaa agcgtcctct
     4081 acaggtcttg cctgtgcatt tgctctataa agtactgcaa aatccttata aggtctattt
     4141 tcttttctag ctatttgtgc aattgaatca gcaatgaaat cagcctcttc tatttcgcta
     4201 ccagttaatt gtatctttat aagttctcct tctttttttt cactccaaag cttttttctt
     4261 tttctttcta tattattaga tataacttta ttagctgcat ctaatatcac ttgtgtagac
     4321 ctataatttt gttctaactt tacaacatgt acattgtcat aatctttctc aaattcaagt
     4381 atgtttctta tatctgcgcc tctccatcca taaatacttt ggtcatcatc tccaacaaca
     4441 caaatatttt gatgttctct tgctaataat tttatcaatt catattgagc tttacttgta
     4501 tcttggtact catctaccat tatgtatcta aatctacttc tgtaatatgc taatacttca
     4561 tcattagcct tgaaaagttc tacagtttta agtattaaat catcaaagtc aagtgcacta
     4621 tttcttttta aacggtcttg atataacgca taaatatctg caatcttaac cattctatta
     4681 tctgccatgt tgatatcttt aaactgcttt ggagtataaa gtttgtcttt tgctcctgaa
     4741 attgcactta taactgcttt tggttcaaac actttatcac ttaaatttaa ttcttttaga
     4801 cagtctttaa ccaatgtaac ttggtctgct gaatcataaa ttacaaaact tctattgtaa
     4861 ccaatcttat ttatatcttt tcttagtata cgaacacagc aagaatggaa tgtacttatc
     4921 cacatatcct tagtttcagg acctatattt tgttcaactc tctctctcat ttcatttgca
     4981 gctttgtttg taaatgttat agctaatata tttggtgctt gtacaccttt atcttctata
     5041 agatatgcta ttcttgttgt taatacctta gttttacctg aaccagcacc agccagtata
     5101 agtactggac cttcagtctt ttctactgct tctctttgag caggatttaa tgtatctaaa
     5161 ttcatatttc tcctcctgtt aacagccata aatatatttt aatctaaaat atgaattact
     5221 tcaaattata attatgtatt atattaatag attatttcca atatattaca attaaataac
     5281 atttttccat ataatttatt taattgttta ataaaaaaaa taaccttatg atttggggaa
     5341 tcataaggca cctttaaggg gtctaggtta agggttatta tatataaatc tattttttta
     5401 aaataggttt agggcttaat tatttatttg tattaagttc tctttccttc caatacttat
     5461 acaaatcttc ttctttctta aataagggta aattcatatt tctatgtact tttactaacc
     5521 atggggattc taggccagct tgtataatgt tattttcatt tacaaataca ttttctgcct
     5581 ttccttcatc aattaaaatc cccttatcca atacatatat ataatcgcat atttcataca
     5641 ttaaattcat atcatgactg gatattacta tttttatatt atctttattc aatcccttta
     5701 ttatatctac aatagaccta gtacttactg ggtctaaacc agctgtaggc tcatcaagca
     5761 atataatttc attttccatt gctataactg atgctatcgc tacccttttt ttctgaccat
     5821 aacttaaaaa atgtactggt ctatctataa aatctattcc attaacagct actagagctt
     5881 tgtttattct ctctttaatt attttttcat ctataccaat atttctcatt gcaaaggcta
     5941 tatcatcata tacttttgaa taaaaaattt gtttttctgg gtcttggaac acaataccta
     6001 cattttttct aaggttgtat aaacttctct tatcatattt taacttttct tctttaaaaa
     6061 gaatttctcc agatgtaggc tttaatatac ccattaaatt cataaataat gttgattttc
     6121 ctgaaccatt tgaacctatt atacctataa catttccctt tgaaaaatcc atattaatat
     6181 ttaatagtgc attggtattc ttttcatatt gataagttaa attatttatt ttaaacatca
     6241 ttatccccta ctatgtgaaa tttaccatca tacaatttta tgtctaatga tatacacata
     6301 tcatcatacc ttgtcataag tcttttgtac agcatactgc caagaattcc taatgattta
     6361 tatgaagttt ttaaatttat gtacccaaat cttagttctt gtgacttata tatttctgaa
     6421 aattcttcta aaaatatgaa tataaaccta tatattaaca ttgatagctc aacaaaagta
     6481 tcaggcaaat gcattttttt aaagaagaat attaattgat taaaaggtgt tgtaagtata
     6541 caaaagtata cacaagtcaa acaagacata gctctaaata acacatgaat agacatgtca
     6601 atagatgctt ttgatattcc tacattgaaa ctaaaaattt caaaactata taataagtct
     6661 gccttattaa aagatatatt tacaagagtt attcctatac taagaaataa aaagtacatt
     6721 ggtattctga gtaattttaa ataattcttt aaatctattc cagctacaca aacaactaga
     6781 atactcatta aaatcataat tccacttaaa acaaatatat tttttattac catagaagca
     6841 atcagaaaga ttactcctat ggctactttt ttatttggat ttactttact taatctattt
     6901 gtatatgcat atttatcaat tataagcata attaacttct ctttcctttt tgaacaccta
     6961 atatgtaccc tattacacca gcacctaacg ctgcttgtgc agagaataat aaactttcta
     7021 tttctccact tggtggctca tatgggctac taaaccatgg ttcataatct ggatttatct
     7081 tagtaatttc actctcagct tgaccatctg ctcctccata ttcagctccc gaattaacaa
     7141 gtaatgggaa tatgataaga gctactacta ataaaagtag taatatatta gttttcgtct
     7201 ttgttttagc actcattagc tttaactcct ttatcattat tttctagtat gcttttttct
     7261 ccattttctg taattaaatt atatacaatt acagtaagaa taccctctgc tattgctatt
     7321 ggtatttgag tcataaagaa aattcctaaa aacttaattg ctgaagccat cactccacct
     7381 gatgggtctg ggaaagccag tgctaactgt atcgaagtta ctgtatatgt agccaaatct
     7441 cctattgctg ctgcaagaaa tactggcatt gcattatttc cgtctttttt ctttaatgct
     7501 ttaaatatta agaatgatat aattggtcct ataatagcca ttgaaaaagc attagctcct
     7561 aaagtagtta ttcctccatg tgccaatagt aatgcttgga atattagaac tatagttcca
     7621 agaacaaaca ttacacttgg tccaaacatt attgctccaa gacctactcc agtaggatgt
     7681 gaacaacttc ctgttactga aggtatcttt agtgctgaca atacaaatac aaatgctcca
     7741 cacagcgcta ataatacttt ctttttaggg tcttgcttta ctatttttcc tattgatttt
     7801 agtcctacta aaaaaaatgg tataaatata actccccatg ctatagacca ttttactggt
     7861 aagtatcctt ccattatgtg cattgcattc gatgtaactg gagttaaaac gattaacata
     7921 agtgcagcta taacccctaa tttgatattt tgtttcattt tactatcccc tctctccctt
     7981 tctaataatt aaaatataaa taatatatgt ctgatttatt ttaaaaataa aaataaaaaa
     8041 gcctaactcg atggctaggc ttctaatttt cgataatcca aatacaaaca cataaaatga
     8101 acatatctgt ataattatta taagaaactt tctccatccc cgaagaaatt actttaatat
     8161 tttaggcagg tctcctgact tagcttcttc ctactcctct tccttcccat gagatataaa
     8221 aaatatcatc atagtggcta acaaaagttt cgtctgcatc acagtagcgg gggctgtaaa
     8281 ggaatttaac ctttttccct attaatcttg cttaaagaac ctataatatt atatatttaa
     8341 tttttaaatt attcttaaat cattttctat ataaatcatt gtataccttt tctgtgaaaa
     8401 tttctacatt ttttataaat tttattcatt tttatatttt tatgtatata aattcttttt
     8461 tgtaagttta ttaatttcta attatcttct ttaaatacat tgaaactaca tcagaaaatc
     8521 tagttatatc tcttgaatat ataaaatcat ttccatatat taatctttca gcttcaagtt
     8581 ctgattcttt tcctgtaaat actcctagta ctaatatatt ttgctttcta gcttttctca
     8641 cttcattggc tgtatctctc aaaccaacta tacccctata agccttttct cctcttaatg
     8701 ttctctcact actttttcct atctttacat catttggtct tccatcgctg agaactatca
     8761 ggattttatt ttcttcatct ctatttatta gaccactaca tatagatttt attgccaaac
     8821 catctctatt attaccagca caaaaatatt caaatatatt ttcactattt tttatactat
     8881 catcataatc tttaaatctt tttaatattg tatagtctaa aaaactagaa aatcccatca
     8941 ctctatttgg tatgccaact tctgttagag catttgcaat tatgtaagct tgaattgcca
     9001 catttccctg atttctactt tgagagccac ttgcatccaa taatatatca ataacgtatt
     9061 tccctttttc attttctata tctttataaa atattttatt attattactt ctaccaactc
     9121 tccaagctct atttgctaat atagtaccac aatcagaata tactctactt ttagcatttt
     9181 cttctattaa aattcttgac agactttctt ttaatctctt tatttgctgt ctatacattc
     9241 tagcatgttc tctaaatttt cctaaattat tttctttttg tcttgttaca tattttagtt
     9301 gaaatacatt attacactca cttctaagaa ctccatctgt aaagtgtatt ctacaacctt
     9361 catgaacatt tctacaattt tgtgtctcaa tttttttaat ttcaccttta ctcaaataag
     9421 tttttccata ataatgttct atttttgaat atatcttatt tgcagtgtct tcatcaacat
     9481 atataactcg gtctgctgaa ttgctacatt tagaatcatc aaaatcccct acaccttcta
     9541 caagcatgga tgaagatatt gaatctatat cactttcaat aatattttct tcttcatcac
     9601 tataaagttc ttcatacatg aaatcagcaa atgtatcaaa atttacttct acactttcta
     9661 cattattttc atcaataaga ctattttctt ctccatttaa tatgtattcg aaataagtta
     9721 aatatataac atctaatgct tttaaaatct ccatcatatc ttgattggta tctatatttc
     9781 ttatatcatt aactattctt ctagtcatac tatctaatgc tgggtgcttg tccatattat
     9841 aaagtacaaa tgtgtattta attttatcca taatattatc attgtgtatt ttggtaaaac
     9901 gtgaaacaat atctttataa gcatttcttc ttatgtcttc tatccctggc ctatctttaa
     9961 tgaccttttc ttcaactatt gtatttaata taacttgaat tagacccagt ataatatctt
    10021 tgttgtatcc ttttcttatt ctatttgtaa gatatttttt aactatatcc caatctacat
    10081 actttcttct agcacctgca attattgcaa aatatagacc tatttctttt gaagagtaat
    10141 ctttttctga tatatctata ctttcattgt aatcaccagc tattgtccat gataagttat
    10201 tagctctatt ttcaaattca taatcatcat atatccattt cataatctca cctatattaa
    10261 atatgactta ttggaaatac atctatactc tcccatttat taggtattct agttttaatt
    10321 acatctccaa ccatttcttt ctcatataca tcaaaagtct ttcctgtaag tcccatatta
    10381 attgcaagag ttggttttaa tcctcttctt atagtcttaa gagatgccat aagaccacgt
    10441 aaatcaatag ctttactaga tatctctcca ttttgagact tcaattgtaa atctaaaaat
    10501 attcctgcaa agtgtattaa tttttcttca tcagcatctg aaaattcatt ttttaaaatc
    10561 atcattaact tatcttcttc tataggagga atatctatta ccataaatct agataccagt
    10621 gcttcattaa gttcttttgt tcctgcatat tcataattca tagtcccaat aaatcttgtt
    10681 gctggatgta gattgactct ctcataccca ggtacatcaa ttattcttct atagtctaaa
    10741 gctgaatgta ccacaactat agcatcattt tttgccatat taatttcatc aaatactcca
    10801 aaacctccat taatagcaca ctcataaact gagcctcttc taagtttaac ttcattgtct
    10861 ataaatgtat ctgtacctat aagtgttgaa ctgtctgtat ttatatgaaa tgatgtattc
    10921 cactgaggtc tattaaatat ttcccctaga ttatcagcaa gtaaattttt tcccgttgcc
    10981 tttggtcccg ataataatat attttcttct tctaaaatag ctgctataca catagacaag
    11041 atatctttac cataaaaata agttttagac tttgttactc tgtattctaa atctttttct
    11101 aaaccataat aatttctaaa atacagtaca tcttcaataa gtttttcatc taccccttgc
    11161 acccttagat tatctattat atccatattt ttaccccttt tatataaata gtatttgttt
    11221 catttcttat caccatttta gcataaaagg atataagcta aaattgattt tttaatctcc
    11281 cccattttaa gtaaaaccat gcaccatttt atcactacaa aattaagagt actacttact
    11341 gatatttctt gattttgttc gtctatacgt atataatata tgctgataaa ttatgaggaa
    11401 aggatgattg aaatatggaa tatatgtctt gcccagaagt agcaaaaaaa tggggcattt
    11461 ctgaaagaag agtacaaaaa ctatgtgaag aaagtcgcat accaggagtt tcaaaactcg
    11521 ggtatatgtg gctgatacca aagaacgcag aaaagcctgt tgatggtaga gcgaaaagaa
    11581 gaaaggaagt acaatatgaa tagcgttttg attatagatg atgacaaaga actttgtgct
    11641 cttatgaaaa aatgtgttga gcaagaaaat ttatctgcta ttactgcaca ttgtggtgca
    11701 gaaggtctac atttgctcga taaaaataga cacacactct ctcttgtaat tttagacata
    11761 atgatgccag atatagacgg ttttcaagtt ctgaaaaaaa ttagagaaac aagtaatatt
    11821 ccagtaatta tgcttactgc taaaaatgac gaggatgata aagtttccgg actacgttta
    11881 ggtgctgacg attacctaac aaaaccgttc agcataaacg aacttatggc tcgtgtcaat
    11941 tctcttattc gtcggtatac tatgttaaac cctgctttta taacagacac agattgcata
    12001 ataataaatg gcatgattat tgacaagaca aaccgaattg tttctatcaa taatattcct
    12061 gttcaactta caagcaaaga atttgattta cttgcttttc tggcttctaa taagggacgg
    12121 gtatttacca aaaaacagat ttatacacaa gtatgggaag aagaatatgc ttttgacgat
    12181 agtaacatca tgtctttcat cagtaaattg agaaaaaaga ttgaaccaga ccccaaccat
    12241 ccattttata ttttgacagt tcgtggtgtc ggttatcgtt ttaataagga ggcttaacat
    12301 gaatacaagt gtctatctac ttttgatatt ggctcttagc ctgattatta tagcgtacct
    12361 tgtttctgtc ctgctacgtg tccgaataca acttacactt ataaaagatg ctttagagga
    12421 tataaaaaat ggaaacctta atcgccgtat tttaacagat gaaaacgaca ttacaaaaca
    12481 aatttgctat gatattaacg aaatagcaat caatagccaa tttcaactta ttcagcaaaa
    12541 acaatcagaa caagcctaca aacagctaat gacaagtctc tcccatgatg taaaaactcc
    12601 acttgcttct ttggtcggtt atttggaagc agtagaaagt aaaattgttg taggagagga
    12661 aaaagacgag tatatccatg ttgcgtctaa taaggctcat tacttaaaga attttgtaga
    12721 aaatctattt gaatgggtaa aattggattc taaggaacaa gtttttcatt ttgatatttt
    12781 tgacttgaat gaattatccc gtaatattat atctgattgg atacctgttt tagaaagcag
    12841 tcattttgaa tatgaatttg atataccaga aatagagtac ttcttacgta tagacgcaaa
    12901 tgcatatacc cgtatcatta ataacctatt acaaaatatt attacccata gtagtggcaa
    12961 caaaatgaca ttgagaattt ttgaaaacaa agagcaagct caaattataa taacagataa
    13021 tgggaaaggt atatcttcag acaatctccc acatattttt gaaaggttgt accaatgcga
    13081 ccattcacga gcttcaaagg gaaatggttt aggcttggcg attgcaaagg aacttattaa
    13141 cgctcataag ggaaatatta ccgccaacag cactcccggt atgggaacag aatttacaat
    13201 attgcttcct aaagccctgt aaaagtacga ggctttctta ctctaaaaca agataaaagc
    13261 aagattatgg caaggttttg gcaaggttca tgttttataa ttctaattgt agttgatttt
    13321 gacgttgtat caactatctt ttgtagaaac aaatttatta aaagtgagga aattatatat
    13381 gaatgatttt gtgattgaaa caaagcaact tacaaaaatt tatgggaatc aaacagtagt
    13441 tgacaaagtc aatctccatg taaaaaaagg ccgaatatat ggtctgttag gacgcaacgg
    13501 agctgggaaa accacaatta tgaaaatgat tttaggattg acttcaatca cgtatggcga
    13561 ggtagatgta tttggagaga atattaaggg atgtgaaaaa cgagtatatc cccgtatcgg
    13621 tgcaattatc gaaacgccag gattttatcc taatctgaca ggaacggaga acttggagat
    13681 ttttgcaaaa cttcgtggta cagccgcccc taattctgta aaaagagcat tggagattgt
    13741 aggcttacct tataaaaata aaaagctgtt tagtaaatat tcacttggca tgaaacagcg
    13801 acttggtatt gccaacgcta tcctgcatga cccggaactg ttagttttag atgagccaac
    13861 caatggactt gaccctattg gtattgcgga gatgagaaag tttattaggg acttgagcgt
    13921 tgagcatgga aagacaattc ttatctccag tcatattctt tcagaaatct cattgttggc
    13981 tgatgatatt ggaattatcg accacggtgt tcttttggaa gaaagtagta tgagtgaact
    14041 agaaaagaaa aacagtaaat atatcctgct acaagtttca gatattccaa agacatcact
    14101 tattttagag cgtcaattta acacgaagga ttattccgtt caagatgacc acactttacg
    14161 cctttataac actactctgg atatgggtga aatcaataaa gcacttgtaa tgcagaatgt
    14221 aactgttatt agttctcaac tttgtaatga tactttagag gactacttta aaaaaatcac
    14281 aggaggagag ggcattgctt aaacttattc aaacagaatt tcttaaactg cgtcgtagga
    14341 aacttatttg gctgatgttg ttgtctgctc tcattatgcc gtttttcgca ctactatact
    14401 tcaattattt tggtaaaaca ggtgttgagc caacaaagtt ttataaatgg tctgcatttg
    14461 gttatacact ttggattatt ttgcccgttg ttttgggtat attttgcacc atgcttatac
    14521 acgaagaaaa ccagtatgat atgctcaaac agctttggat tgtacctatt agtaaaatgg
    14581 gatacttttt tagtaaattt ttcgttgttt tgatttactc tatttgtttt atgctgatta
    14641 cagccgttgc ttctgtgtta tttagtgtac tttctggata tgtcgtattt agctgggcaa
    14701 gcattttata tttgttgaaa aaatgtttag aaattggtgt aatcactgct tttgtaatgt
    14761 tgccgatttt ggcaatcgct acatctcaaa aaggatacat tctcccaatt tgtatcacat
    14821 tggtatatgc cttttccggt tttgttataa tgacaataaa tatgtattta cacccattat
    14881 ccagtatggg agttattatc atgagaaata aagacattcc aggtcttata ttttcacagg
    14941 aaattaatgt cccattagca tttctttgta tttgtatttg gagtattgta tcagtattgt
    15001 ttgcaagcat tgcactagga agaagaaagt gaggtgtaga taatgtggaa attactttgg
    15061 gctgaatgtc aaaaaattcg tcgttcaaaa attgtttgga ttacattttt tgcatccatt
    15121 atgatagcag tcatagtttt tgcaggaggg caggatgtat ataatgaccc agatttacat
    15181 tatggcttaa agagcgttta tgacggttca cggtatatag acaatgcagg ttggtatatg
    15241 gacgcggtac aaccttggtc aacttttttt gttcttcctg ctgtcattgc cctattagga
    15301 agctatatta tttgtcgtga agaagaggag gacactatta aatccctgcg tcttattccc
    15361 ataaatgaaa caaaattaac catagcaaaa atgattatta cttttatatt cagtatactt
    15421 ctttatttgt tactctttac tataacattt ttgactgaat ccgttttaca tttttccgat
    15481 ttatcgacaa aactggtttt aagttgcatg aaagagtatt ttcttgatgg cataggtgta
    15541 ttctttgcaa tttctcccat tattgccttg gtatcgcgca tgaaaaaagg atattggctt
    15601 gcattagtat tcacagaagt ttattctatt gctggactat ttgcgggtat gtcaaatgtc
    15661 ttacaaacct tttttcctat tgcagcaata tttaatattt ctggatacta tataactact
    15721 ggagaaaaaa ttatggggag tatcataagt ttattacttt gtgcctgcct ttctgcattt
    15781 atactgaaag ggctaaaaca caatgaaaaa aattgaaata ggtatatcaa aatgaaaaag
    15841 ataaaaaaac tgattattct aattgtattc ttgtttcttt ttggcatgtt acactgttat
    15901 actgaatgga aattcaacaa tgacccacct aaaggggtaa tagaaagaat aaatgagtgg
    15961 actgataaga ttggactgga ttagtaactt atgttaatta tagtgaatgt aatattagca
    16021 agttattgtt tcgtatttta atactataac tttaaatatt tggttttaat cttccgaacg
    16081 aatataaaaa aactgtcaca gaggcaacat atttttgaat atttataaag tggtagtttt
    16141 gattttcaaa gctgccgcct tttcttctat ataagcaaac ttatcctcaa caaagtgtaa
    16201 aacatggtac attttaagaa aaaagtacca cagacacaag caataaaaga aacgccgaga
    16261 acctacaaaa acgtagtgct tatgcagatt tacgacgcct tctattttct caaccgtctt
    16321 aatgaccttg tacaaaagaa atttttctaa tattttttat aatcttatct tgtgatgttt
    16381 tttatgtata aatgacttaa taacaaatcc aataaaaatt atggatattg gtataattag
    16441 aacgaggaat ttataatcat tataatgtga cattattctt acccaactct cagaaaaaat
    16501 atatcctata ctgattaatg aagtattcca tatggttatt cccacgatag atgatattac
    16561 aaaagttata atattttgac ctgctatacc tgctataaaa gatatgtatg ttctacataa
    16621 agggattaat ctacatacac aaacagaaat agaagagtat ttattaaaat aatcttgaga
    16681 tgcaaatatt cctttctttg cctttggaca tatctctatt attttattta tgatagattt
    16741 acctccccaa tttcccactg tataacaaaa tatcgaacca agtatacctg caattatact
    16801 taaaattaaa attgtcagaa atccaaaatg atttcttgca gcaattgctc cacataaagg
    16861 taaaacaact tcgctaggta atggaaaaca agcatactca atcataatta atacaaatac
    16921 agagattaat ccatattgta aaataaaact attgattaca gacacttact tatctatctc
    16981 ctttcttatt taaaggtttt aagggtacat attctaagga ttctcaccct atatttaaag
    17041 aatcaatctc tttaaactat tatatgtatt tacacaaagc atttataaca tactttaaaa
    17101 atagtacctt aaaataagaa acttaataaa taaaaaaa
//
LOCUS       DAMJWO010000088        17067 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.090, whole genome shotgun sequence.
ACCESSION   DAMJWO010000088 DAMJWO010000000
VERSION     DAMJWO010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17067
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.090"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            61..930
                     /locus_tag="PC366_003065"
                     /pseudo
     CDS             61..930
                     /locus_tag="PC366_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426876.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
     gene            1836..2543
                     /locus_tag="PC366_003066"
     CDS             1836..2543
                     /locus_tag="PC366_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2578561.1"
                     /translation="MIFTKSNKYDKDFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLAKEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISIDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSITWWNKLWSESESVIVEKCEALNCHDEAWKDWINCDNSYAINDKKMME
                     VENGKYFNTISLIARTK"
     gene            3155..3655
                     /locus_tag="PC366_003067"
     CDS             3155..3655
                     /locus_tag="PC366_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2578562.1"
                     /translation="MIEGIKFIKAEEKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNTINKNLPQLFIIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSSLL
                     KQIIDLSKEYGYEKIELDVFKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
     gene            complement(3905..4684)
                     /locus_tag="PC366_003068"
     CDS             complement(3905..4684)
                     /locus_tag="PC366_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578563.1"
                     /translation="MNKNILNNSFPEVPESFHNSLSKTLNSLPEREENYKMINNKTHK
                     LPFRKGLVATLAITLILSTTALAVGHIYSLVGKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNKKALDKENNVLGKSKALSFEYKNGNDEISLDTANNVLEKS
                     SDNLKVVDTYKDINISYEAFAQKFVPEGYKMTEQDKIDEKSGKYTFSVGPNNESDKVE
                     VNEFKFLTWKQDGVYYSFTVQDSNLSMNDLVKMAHEVIDAK"
     gene            complement(4681..5160)
                     /locus_tag="PC366_003069"
     CDS             complement(4681..5160)
                     /locus_tag="PC366_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2578564.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAVNNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKSLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRTLLKTKLENTEVII"
     gene            5966..6667
                     /locus_tag="PC366_003070"
     CDS             5966..6667
                     /locus_tag="PC366_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HDF2578565.1"
                     /translation="MKFQEMINSPGLWIVSSFLVIISVVQAIVFMKSALKEASNLGIE
                     RKGIKAAIRSASVTAIGPSLSPVITLLSLVAVIGAPTTWMRLCDVGAARTELGVISLT
                     SNLSGVEVGSAAFGAEAFSYALWGMALNNLGWLLVVFILGHRMRGIVEKMNVKYNPTW
                     VKKLLAGATVGLFAYLLSNQIKTFEIPKLTPAVISAIVMLVLTTLFKKNQRLQELSLG
                     IAMLIGMFGTQIVLS"
     gene            6693..7349
                     /locus_tag="PC366_003071"
     CDS             6693..7349
                     /locus_tag="PC366_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578566.1"
                     /translation="MYDKKMIKIGRISIGLAIIANFIPAIYVGLRFGQMPMLSVIFQI
                     WGLVATTYGVSWIVQPIAYYPTLGAPGSYIGWLAGSVGDIRMPAASMAQKIAGVEAGT
                     HEGEVVGTIGTCCSIFVSASMITIFTIVGYKVIPLLPEFITDSFNYILPALFGAIYVD
                     IARKDIRAGGCTIAVALAIMYFGEKIGIPGGLLTLFIVLGGILITRVFFVIDSNKTKE
                     "
     gene            7556..9196
                     /locus_tag="PC366_003072"
     CDS             7556..9196
                     /locus_tag="PC366_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HDF2578567.1"
                     /translation="MFDVKIANGIIIDGTGNSRYKGDVGIVGDKIMAIGDLSQKEAKE
                     TIDATGKFVSPGFIDFHTHSDLSLVYDKYTRSRIHTGVTTDVIANCGIGVAPIREEKK
                     QELIDYLGTRIIGTIPIKLNLHWNTMQEYFDYLTENSPAVNVVAYVAQGPVRINEMGF
                     SKEPATLEQLKNMKLEVRKAMEAGCVALSSGLVYLPGAYTKKEEMAELCKELIPYNGY
                     YISHIRDEGDEEMEALDEAIYIAKTAGVPLHISHLKVMGHKNFGTIDKVFKKLDEAEA
                     DGLEVTFDCYPYTAGMTSLGALLPPWAFEGGVENMVKRLEVQENRDRIIKELEEGIPG
                     WQCFYQLAGGWDGVVLASVMTEANKYVEGKTLMEVAKINGENPFDTFFRLLIEEKSKI
                     QVVVHTQGQEDTDKVVCHPKSCIGSDSMDLSTEGLLSLGKPHPRAFGTFGRIFSYYVR
                     EKGMLTFEEAVKKITYLSAKRLGIYKERGLLKENYFADIVVFDPDTIEDKATYSNPKQ
                     YTVGVEYVLVNGKIALAGGKQTDVCAGRVIKNPLSIAK"
     gene            9555..10877
                     /locus_tag="PC366_003073"
     CDS             9555..10877
                     /locus_tag="PC366_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578568.1"
                     /translation="MKILYVGPGMVIDKILAVSKKNFPNIEADFLRYDRYIEVPDLLE
                     KYRGRVDAVLFTGKSPFKFFEKRQKDFVLSDYIPRHETTLYRVLLEITYLLKFDISRL
                     SIDTYDKAMLKRLYKEIGVEFKDEHMFFAEQKYLEEDYIKFVLEFHKYNYQNNDICCC
                     ITGLEEAYHAMKKENIPVVLALPSEDVMVQSIKNIQMRYIAKKNNENQIVVLAIKLNM
                     PSEYSLMKEDEYAYLSQRIKILDKLYHFNSRIDGVLVEQSRSEFMIFTTKKILELETK
                     KYRDIYLLDMIREVSVINTYIGIGYGKTANEAKFNAYESIKMAQSQKNDAAYVVFENG
                     EIMGPLKPNPAVKEKNSFDERFYQIATETGLSANTVYKVFNKIINSGKTEFTSKELAI
                     ICGVSIRTMDRIILRLCDSGYCEVVSEQLMSKYGRPSRILRFKPFLLF"
     gene            11074..12081
                     /locus_tag="PC366_003074"
     CDS             11074..12081
                     /locus_tag="PC366_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HDF2578569.1"
                     /translation="MGKYQDSKKVVRNYFEALENATGDEVENVLKQHMKSDYNWKGVY
                     PFREQEGTENVADVFWKPLKKSLSNMQRRQDIFIAGTNEIDNSEWVMSMGHFMGLFDK
                     DWLGIKHTRKMISLRYAEFNCVQDGKIAKTGLFVDIIGFMIQAGVNPLPPQTGSYFVY
                     PGPIDHNGLLFEDADEVEGVKTLALVNKMVDDLSELNESGTMGCPPEILKKSWAKDMI
                     WYGPGGIGASYTIPRYQEQHQLPFRNNLKGKTFNGHVCRFAEGNFACFFGWPNLTNVP
                     CGGFLGLPGGEVKADMQVVDVYYRKGDKLQENWVLIDIPYWLKQQGLDILERTKSIFN
                     A"
     gene            12119..13516
                     /locus_tag="PC366_003075"
     CDS             12119..13516
                     /locus_tag="PC366_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ester cyclase"
                     /protein_id="HDF2578570.1"
                     /translation="MASTNKNNVTSKEEEKEVSTSGLESCTVKENKAKMNQTNFSNIN
                     ENQTNENKTNTYKGNIDKINTNKSDINKVNIDTVDTDKLNTNTLTEKNKKVIFKGEDN
                     MSSTKIYYGDSLEVTPVGVMDYNDFSKQTKREQEIPGFDSKYRDFVDYIMKITHNIWE
                     EKGIGVIYDTYHNNVTMHCGSSNLVGIKDVISNTLQTLHAFPDRRLIGQNVIWSNFGA
                     DGFLSSHRVLSTATNLGDSNFGPATGRKINFRTVIDCATTNNRIHEEWLVRDNLWIVT
                     QLGLNPQEVAKSMAKASESKVLSLQSTYGICESMDGQFMPTKYQAKDDSVGEMMLEMT
                     SRIYNYKYINEVKKYYHDNAVVHFICDKDLNGYDEIQGMIVSLLASIPNGSYEVERVT
                     CNQREKNEGYDVSIRWRLRGINEGIGFFGQPSGKHIEVMGINHYHILQGKVKEEWITF
                     DGMDVLKQMYMGVEE"
     gene            13661..14926
                     /locus_tag="PC366_003076"
     CDS             13661..14926
                     /locus_tag="PC366_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2578571.1"
                     /translation="MKTTVEIENDIILGKDYSNLKRGIAFFSIALIYFFYCYNFMVGT
                     FIKPTMIYALADGGFGFSLKQTEEIFAVMSFGTIPGTFIFGVISTKIGKKRTLISVAL
                     LIGLTTFIPMLSPTDIMLWKIARLCTGVVLGGVFGTAMPLVADMFPSKYRGKLAAILT
                     ALFSLAMIFGGKVYGVLGDANWQILMYTAIIPPIVGAILAIFFVPDDLEYTKELVKKG
                     KETGEKISYISMYKGKYLWIGLGTILLSGANFTAYSAFSNNATTYLVTGIGMSAAVAG
                     SIYSLQGIGQLVGYLFWGSIADKFGRKIPFIGMALAAVFVFIYTKLGGDNTTTFYMIS
                     VLLGVAVGYSGAWGAYYTELFPSKYRSLSSGMSFNGGRIISTFAIPAIAGTASGTLGM
                     MTIFYISIAVFVAGAIVWLFLPETLNNKK"
     gene            14968..16007
                     /locus_tag="PC366_003077"
                     /pseudo
     CDS             14968..16007
                     /locus_tag="PC366_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432878.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
     gene            16042..17064
                     /locus_tag="PC366_003078"
     CDS             16042..17064
                     /locus_tag="PC366_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2578572.1"
                     /translation="MNQKKVHYNKSATSKDVARLAGVSQSSVSRAFGSANGKGVKPEV
                     RERIFRVANEIGYVPNLVARGMISGKTNVIGLIVGDSLGPFYNRIINLFVEKIQEIGK
                     QCLVFKVPRQQSIDSIISKVIQFQVEAVIITASAMNKVMAETCEENNIPVILFNRFIP
                     GIKISTVYVDPIEGGGMVAEYLLKKGHKNIGYIQFTRETSEEMEKKIGFYSKLRQSGI
                     HNLKEESANYDYDSGYEAGKRMLALSNPPTAIFCTSDLIAIGVMDAARFEYKLRVPED
                     LSVIGYDDIQMASWKSYNLTTIRQPLDLLIEKTINILKSLLNEENPESVVEMLKPELI
                     ERGSTL"
BASE COUNT         6268 a         1874 c         3120 g         5805 t
ORIGIN      
        1 aaagtttatt atcggaaatt tctatattaa tatgtagtaa ttcaatatta ttataaagga
       61 gtggttatta ttaaggcaat tgaactttat aaaaaattag atttagaatt taatattaaa
      121 aatattaatg atgattggag ttttatgaat tttgaaaatg attttatcac tccagaattt
      181 agaaaaaagt acatatgatt agtattagat aatgctcaaa atattaataa agtatacaca
      241 actacttttc ctgataaaga aataattaag caagttatag ataaagatga aaaagatatt
      301 ttaatttttt cacatcacgc aatgggatac atagcatcag atgaaggttt tccatttcac
      361 gacataccac tatcttatat ggaagagatg aaaaatcgta gaatttcttt ttatgtatta
      421 cattctccac tagacaacta tagtgactat tcaacttctg ttagttttgc aaaagctatg
      481 ggtttagaaa tagtcaaacc attttgtaaa tatgacgata aaattgaggt aggagttata
      541 tgtaaaacat cactaaaatc aatagaagag attaaggaat taattaaaaa atctgttggt
      601 catgatgtga aattgtatga ttatggagat tctgtattaa aagatggttt agttgctatt
      661 gcagcagggg gaggaagtta tccatttgta gcaagagaag ttgctgaact tggtataaat
      721 ctatatatta ctgggtttac taagccttta aaacattttg aaccagtatt agagttccat
      781 caaatagcaa aagataattt aattaatgtt ataggtgcta ctcattattc tacagaaaaa
      841 tttgcgtgta tgggcatggt tgattatttt aaaaatctag gtttagaatc agagtttttg
      901 caaggaaaat attacttaga ggatttatag gacatattaa acaataaaaa taaacagtta
      961 gtaaaaattt attttactaa ctgtttattt ttttacctat ttatccagtg ttttgaaaaa
     1021 atctatcttt attttttaaa ctaagaaaat agacttttaa ttgttgatta gaagatttag
     1081 ttttgatgtc ttttaaatta tttttcgata ttttttagtt tattttttga tgtattttag
     1141 attattattt aggattgatt agaatttata aatatttatt ttagattatt gtaaatattt
     1201 atttaaaaaa aatagaatta ttatatttat gataataaat ggtataataa aaggtaaagt
     1261 gtcaaatatg cactaaatta aataagttaa ttagtatata ggttaaagtg gaagtaatta
     1321 aaacttatta agtattagaa aatgacttct tattagagta agtatctaaa atgatataaa
     1381 aattatgatt actcattaaa gtgactatta tagagtagat aaaattgccc ataaaaatag
     1441 ctataataga gtggataaga ttactcatta aagcaattac tatagagtag ataaaattac
     1501 tcactaaaat aactataata gagtggataa gattattcat taaagcgatt actgtggagt
     1561 agataaaatt actcactaaa ataactataa tagagtagat aagatactca ttaaggtgat
     1621 tattgtagag tagataaaat tacccatcaa agttaattat cacatattag ataagattat
     1681 tcattaaagt tactatcaca gagtggataa aattacacat taaaattgtc tgttaaagaa
     1741 tgaataaaaa agagattgct caatataaga agcatataaa aaatcaaaca tataaaattt
     1801 aataaataat aactgatagg gaaaggaaag atagaatgat atttacaaaa agcaataaat
     1861 acgataagga ctttctcatg aaaaatatga tgggacctaa ttgtataaaa atattggaag
     1921 aattaacaag taagataaaa ctagaaaagg gaatgcgtat tttagactta ggttgtggta
     1981 agggtatatc ttcgatattt ttagcaaagg aatttgatgc tactgtattt gcaacagatt
     2041 tatggataga accaactgaa aactataaaa gatttaaaga gtttaaattg gatgataaaa
     2101 tatttccaat acaggcagag gcacatgaac taccttatgc agaaggtttc tttgatgcgg
     2161 tgataagtat cgattcttat cactattttg gaaacaaaga aggattttta gacaatcata
     2221 tatcacctct tgtaaaagag gggggaatac ttgctatggc aatgcctgga ttaaaagaag
     2281 attttgtgga ttgtatacca gatgaactca ttccattttg gcaagataat atgaacttcc
     2341 attcaattac atggtggaat aaactttggt ctgaatcgga gtctgtgatt gtagagaaat
     2401 gtgaagcttt aaattgtcat gatgaagctt ggaaggattg gataaattgt gataattcat
     2461 atgctataaa tgacaaaaaa atgatggaag tagagaatgg aaagtatttt aatacaattt
     2521 ctttgatagc gagaactaaa taattgtgat gaatttataa aagtataaga taagtagaaa
     2581 tataagttga atgagagtat aagaagcata gaaatataag ttgaattaaa gtagaaggta
     2641 aataaaaatg taagttaaat aaagagttta tacaaaaatg attttttaga ttatttatac
     2701 ccaatcgagt tgcttaggtc agttgggtat ttttattttt ttaaagttaa attgcaaata
     2761 ctattgtgtg atatatattt taatactaaa tgtttgtttt ataagaaata aactaataga
     2821 aaaaatagtt ttaacaatga aagcaaaaaa ggtattgatg aagattaaaa attttatagt
     2881 accattttat atattttttt atatatttta ttatacttta aatcaaattt caaaatgatt
     2941 aagtatatat acccaaaaga ttaaagaact atatttatta tactattaaa aattatttta
     3001 atagagatac aagagataga tatattggtt ttaattttat agaaatatac aaagatattt
     3061 taagctaata tatagtaatt tatatagcat tataaactag aatcatataa aataagttaa
     3121 ctacaatcat aaattaaaaa ggagaaatgt taagttgata gaaggaataa aatttataaa
     3181 ggcagaagaa aagtatattt attcgtattg gcaaactttt gataaaatag caaaagagag
     3241 gaaatatcta gctatggatg aagcctttcc ttttgaagaa acagttgaat ttataaaaaa
     3301 tactataaat aaaaacttac cacaactgtt tataattgat ttagaatcag ataactgtat
     3361 tggttggtgt gacgttttac ctaaaactga aaaagttggt tatttaggca tgggtattct
     3421 taaagagtat agggaaaaag gtatcggaag tagtctttta aaacaaatta ttgatttatc
     3481 aaaagaatat gggtatgaaa aaattgagct tgatgtattt aaaagtaata gtagagctat
     3541 tcatgtttat aaatctttag ggtttgtaga ggtaaataca atatctagtg gttttacatg
     3601 gaatgataga cctgtaaaag aagaagtaat tcaaatggag cttacactta tataaaataa
     3661 agttaaagtc tttaaaattc catatacact tgtataaaat aaagttaaag cccttaaaat
     3721 tccatataaa agaaatattt ttaagggctt tttaataatg gttcttttga aggtagctaa
     3781 atatctaaaa ttttatatat taaatttaaa gaaaatataa agatggaaga tacaaccatg
     3841 tttactaata aaaaaattaa agtcataaat aataaactca taaacaactt attattactt
     3901 atgtttattt tgcatctatt acttcatgag ccattttaac taagtcattc atagataaat
     3961 ttgagtcttg aactgtaaaa gaatagtaaa ctccatcttg tttccatgtc aaaaacttaa
     4021 attcattaac ttcaactttg tctgattcat tatttggccc tacactaaat gtgtatttgc
     4081 ctgatttttc atcaatttta tcctgttctg tcattttata accttctggt acaaactttt
     4141 gtgcgaatgc ttcataagaa atattaatat ctttgtaagt atctacaact tttagattgt
     4201 cagaactctt ctcaagtaca ttatttgctg tgtcaagaga tatttcatca ttgccatttt
     4261 tatattcaaa actaagtgct tttgattttc ctaaaacatt attttctttg tcaagtgctt
     4321 ttttatttac agtatatgct cctttaaatt tatatccatt actaaattca gaaactatat
     4381 taggggtaaa gttaaagtct ttttttactt gttctgtagt tgggatagat gtataggtag
     4441 ccttagtact tgattttcca actaaactat atatatgtcc tactgcaagg gctgttgtgc
     4501 tcaatatcaa agtaatggct aaagttgcaa ctaagccttt tctaaatggt aatttgtgtg
     4561 ttttattatt aatcatttta taattttcct ctctttctgg taaactattt agtgttttac
     4621 ttaaactatt atgaaaactt tctggaactt ctggaaacga attatttaat atatttttat
     4681 tcatatgatt acctccgtgt tttctaattt agtttttaat aatgttcttc ctcttgataa
     4741 tctacttttt acagttcctt gaggtatatc taatatttcc ttaacctcat ctactgaata
     4801 accttcaata tagtaaagga ctattggaat tttaattttt ttaggtagac tttgaatagc
     4861 agtatacaaa tcgctatagt catctttttc atcaattttt ttgtttttga agacatcttc
     4921 aaatgataga gattttaatc gtttgcgtct taatgaatta cattcattta tgactattct
     4981 aatcagccat gttttaaagt attgttcttc cttaagagaa tccaactttt catatgcttt
     5041 taaaatagca ttgttgacgg catcttcaca gtcttggtcg tttcctagaa tagacttaga
     5101 tactcgatac aaagtctgtt ctgattcaag tatattgttt gtaaatgtag ttttatccaa
     5161 ctgagttcct tcccttctat gcaaatcgta gcgctacttt tttgcctttc acttattaga
     5221 taaaatttta ctatagatgg ttcacttttt ttatgattat ttgataaatt taagtttgaa
     5281 agttttgcct attctataca aatattctat aatatatttt tttctagtat tttcccctca
     5341 tatataaagc catgtagata tattaaactt tagaagccat ttatatattt agttttatag
     5401 taagtgttta tattaagtaa ttataaaata gtaagtattt gatgttgagt agttagaaaa
     5461 taatgctttt ggattattta cttcatgtat agatttaaaa taagtttttt aattaatgac
     5521 taaagataac ggtattttga ctaaaagtag gcttttaaga aaaaacaatg aaacttaaat
     5581 gagaatcaag agttagaaat gtcattattt tagatagata tgaacataaa taaacttaaa
     5641 aaatataaat tataaaaata ataatttttt taaaataaca aagttttttg attaaaagtt
     5701 ttatattgaa atgtcaaagt aataaaatac cttataagtt aattacaggt taaaaaaata
     5761 atatgtgaat tttctgatat ttactaatta tcaataaagt atttaagtat taatgttttt
     5821 agtgagactt taagacagat aatctcctat taaagatact atatcttaga taaaataaat
     5881 taaaacaata taaaaacata acaagattac agaaagaaag ctcataataa aacactaaaa
     5941 aatttatttt aaggaggaat aaagtatgaa gtttcaagaa atgattaata gcccaggtct
     6001 ttggattgtt tctagttttt tagtaattat ttcagttgtt caagcaatcg tatttatgaa
     6061 atcagcactt aaagaggctt caaatcttgg tattgaaaga aaaggaatta aagcagcaat
     6121 tcgctcagct agtgttacag caattggacc ctctctatct cctgttatta cattattatc
     6181 actggtagct gtgattggtg ctcctacgac ttggatgagg ctttgtgatg taggagctgc
     6241 cagaacagaa cttggagtaa tatctcttac atcaaattta tctggagtag aagtaggtag
     6301 tgctgcattt ggagcagaag ctttttcgta tgcactatgg ggaatggctt taaataactt
     6361 aggttggttg cttgttgtat ttattttggg tcatagaatg cgtggaattg ttgaaaaaat
     6421 gaatgtgaaa tataatccta cttgggttaa aaaactactt gcaggggcta cagttggatt
     6481 atttgcttac cttctttcaa atcaaataaa aacattcgaa ataccaaaac ttacaccagc
     6541 agttatttca gctatagtta tgctagtatt gacgacttta tttaaaaaga atcaacgatt
     6601 acaagaatta tccttaggta ttgccatgtt gattggtatg tttggcacac agattgtact
     6661 atcatgatta aaacagataa gaggtgataa ttatgtatga taaaaagatg ataaaaatag
     6721 ggagaatttc tataggtctt gcaattattg caaattttat tcctgcaatc tatgtaggtc
     6781 ttcgctttgg tcagatgcca atgctttctg ttatattcca aatttgggga ttagttgcta
     6841 caacttatgg agtgagttgg attgttcaac ctatagctta ttatccaaca ctaggagctc
     6901 caggttctta tataggttgg cttgcaggtt ctgttggaga tatacgtatg cctgcagcat
     6961 caatggcaca gaaaattgca ggtgtagaag caggaactca tgagggtgaa gttgtaggaa
     7021 caattggtac atgttgttca atctttgtat cagcttctat gattactatt tttaccattg
     7081 taggctataa agtaattcct ttgttacctg aatttattac tgattcattt aattatatac
     7141 ttccagcatt gtttggggca atttacgttg atattgcgcg taaagatatt cgagctggtg
     7201 gatgtacgat tgctgtagca ttagctatta tgtactttgg tgaaaaaatt ggtataccag
     7261 gtggattgtt gacattgttt attgtgttag gtgggatact tattacaagg gttttctttg
     7321 taattgatag caataaaacg aaagaatagg attgtttact aggaagaaag actagaatta
     7381 tttgctgaga aaaagaatag gattgtttac taggaggaaa gactagaatt atttgctgag
     7441 aaaaagaata ggattgttta ctaggaggaa agactagaat tatttgttga gaaaaaagaa
     7501 taggattgtt tattaagaaa tatgaatata aataagtctt gaaaggagaa gaagaatgtt
     7561 tgatgttaaa attgccaatg gaataatcat tgatggtaca ggaaattcaa gatataaagg
     7621 tgatgtaggg attgtaggag acaaaatcat ggctattgga gatctaagtc aaaaagaggc
     7681 taaagagact atagacgcaa ctggaaaatt tgtatcacct ggttttatag atttccacac
     7741 tcattctgat ttatctcttg tgtatgacaa atacacaaga agccgtatcc atacaggtgt
     7801 aacaacagac gttattgcaa actgtggtat aggagttgct ccgataagag aagagaagaa
     7861 gcaggagtta attgactatc ttggaacgag gataattggt acaattccaa taaaattgaa
     7921 ccttcactgg aatacaatgc aggaatactt tgattactta actgaaaatt ctccagcagt
     7981 aaatgttgta gcttatgtag cacaaggacc tgtacgtatc aatgaaatgg gattttcaaa
     8041 ggagccagct actttagagc aacttaaaaa tatgaagttg gaagttagaa aggctatgga
     8101 agctggatgt gtagctcttt cgtcaggatt agtttattta ccaggagcat atacaaagaa
     8161 agaagaaatg gctgaattat gtaaggaatt gataccatac aatggatact atatatctca
     8221 tattagagat gagggtgatg aagaaatgga agctcttgat gaagcaattt atatagctaa
     8281 gacggcagga gttcctctac atatttctca tttaaaagtc atgggtcata agaattttgg
     8341 aactattgat aaggtattta aaaagctaga tgaagctgag gcagatggct tggaagttac
     8401 ttttgattgt tacccatata cagctggaat gacatctttg ggtgcacttt tacctccttg
     8461 ggcttttgaa ggtggtgtag aaaacatggt aaaacgatta gaagtgcaag aaaataggga
     8521 cagaattata aaagagctag aggaagggat tcctggatgg caatgtttct accagttagc
     8581 aggtggttgg gacggtgttg tactagcctc tgtaatgact gaagcaaata aatatgtaga
     8641 gggtaaaact ttaatggagg tagctaaaat caatggtgaa aatccatttg atacgttctt
     8701 taggcttttg attgaagaaa aaagtaaaat tcaagtagtt gttcatacac aaggtcaaga
     8761 ggatacagat aaggtcgttt gccatccaaa gtcatgtata ggttctgata gtatggacct
     8821 ttctacagaa ggcttacttt ctcttggaaa gcctcatccc cgtgcatttg gtacttttgg
     8881 acgaattttc tcttactatg ttagagaaaa aggtatgttg acttttgagg aagcagttaa
     8941 aaagataact tatctttcag caaaacgctt aggaatttat aaagaaaggg gtctacttaa
     9001 ggaaaattat tttgctgaca ttgtggtatt tgacccagat acaatagaag ataaagcgac
     9061 ttatagtaat cctaaacagt atacagtggg agtggaatat gtattggtaa atggtaaaat
     9121 tgcattggca ggaggaaagc aaactgatgt atgtgctgga cgtgtaatta aaaatcctct
     9181 tagcatagca aaatagaata cattaagaac ttttataaaa atagtctttc tttgaatatt
     9241 aaggaaggct atttttgtta aattaataaa gattactcta cttgtgtttt ctagagaatt
     9301 taactttaag tagaaaaaac aatatattaa ttgtaaaatg taattaatat taatggataa
     9361 gatttaaata caaaaactta aatacaaaaa tgttttaaca gatagtcata attaaaaaac
     9421 ttaaagtaac tttttatata agatataatt gattatgcaa aattttatga agcagcaacc
     9481 ttgttacttt aagtcaaggg aggttcagaa agtgtcttaa gagataatag tatctttagg
     9541 aaaggagaaa cgaaatgaaa atactttatg taggaccagg catggtaatc gacaaaatac
     9601 tagcagtaag taaaaagaat tttcccaata ttgaagcaga ttttcttaga tatgatagat
     9661 atattgaagt acctgattta ttggaaaaat atagaggtag agtagatgca gttcttttta
     9721 caggtaaatc gccatttaaa ttttttgaaa aaagacaaaa agattttgtg ttgtctgatt
     9781 atattcctag acatgaaaca acattataca gagtattgct tgaaattaca tatttgctta
     9841 aattcgatat tagtagactt agtatagata cttatgataa agctatgctg aagagattgt
     9901 ataaagaaat tggagttgaa tttaaggatg aacatatgtt ttttgcagag caaaagtatt
     9961 tagaagagga ctacataaag tttgtgcttg aatttcataa atataattat caaaataatg
    10021 acatatgttg ttgtattaca ggtcttgaag aagcatatca tgcaatgaaa aaagagaata
    10081 ttccagtagt tttagccttg ccttctgagg atgtaatggt acaaagtata aaaaacattc
    10141 agatgcgtta tattgcaaag aaaaacaatg agaatcagat tgttgttctt gctatcaaac
    10201 ttaatatgcc ttcagaatat tcactgatga aggaagatga gtacgcttat ctttcacaaa
    10261 ggattaagat tcttgataaa ctataccatt tcaatagccg tatagatggt gttttggtag
    10321 agcagagtag aagcgaattt atgattttta caactaaaaa aatacttgag ttagaaacaa
    10381 agaagtacag agatatttat ttgttggata tgattcgtga agtttcagtt ataaacactt
    10441 atataggaat tggttatgga aaaacagcaa atgaagctaa atttaacgct tatgagagta
    10501 ttaagatggc tcaaagtcaa aaaaatgatg cagcatatgt agtttttgaa aatggagaaa
    10561 ttatgggacc actaaagcca aatcctgctg tcaaagagaa aaatagcttt gatgaacgat
    10621 tttatcaaat tgctacagag acagggctaa gtgctaatac tgtatataaa gtgttcaata
    10681 aaataataaa tagtggaaaa actgaattta catcaaagga attagctatt atatgtggtg
    10741 taagtattag aactatggac aggattatac ttagattgtg tgattctggt tattgtgagg
    10801 tagtgagtga acagcttatg agcaagtatg gtagacccag tagaatatta cgttttaaac
    10861 cttttctgtt gttttaaata gatataagtt aaaaattaaa tttttatgat aacattttct
    10921 ttacaatttt ttagatatat gttaatattt agaaaaatgc atatgtattc ataaaataaa
    10981 ctcaaaatag ctaaaaaatc attaaaaagg aaatcgtatg cataaaatga gaaagttaat
    11041 ttataactta aataaatctg ggaggagata attatgggaa aatatcagga ttcaaaaaaa
    11101 gttgtaagaa attattttga agcattagaa aatgctactg gggatgaggt tgaaaatgtc
    11161 ttaaagcaac atatgaaatc agattataac tggaaaggtg tgtatccatt tcgtgaacaa
    11221 gaaggcactg aaaatgtagc agatgtattt tggaagcctt taaaaaaatc attgagtaat
    11281 atgcaaagac gacaagatat tttcattgca ggaacaaatg agattgacaa tagtgaatgg
    11341 gtaatgagta tggggcattt tatgggactt tttgataagg attggcttgg cattaaacat
    11401 actcgtaaaa tgattagttt aagatatgca gaatttaact gtgttcaaga tggtaaaatt
    11461 gctaaaactg gattatttgt agatataatt gggtttatga ttcaagcagg agttaatcca
    11521 ttgccaccac aaacaggttc atattttgta tatccagggc caattgacca taatggatta
    11581 ctttttgaag atgcagatga agttgaagga gtaaaaactt tagcattagt aaataaaatg
    11641 gtagatgatt tatctgaatt aaatgaaagt ggtactatgg gatgcccacc agaaatactt
    11701 aaaaaatctt gggctaaaga tatgatttgg tatggtccag gtggaattgg tgcttcttat
    11761 actataccta gatatcaaga gcaacaccag ctaccattta gaaataattt aaaaggaaag
    11821 actttcaatg ggcatgtatg tagatttgca gaaggtaatt ttgcttgttt ctttggatgg
    11881 cctaatctga ctaatgtacc atgtggaggt tttttaggat taccaggtgg agaggttaaa
    11941 gcagatatgc aagttgttga tgtttattat cgtaagggcg ataaacttca agaaaactgg
    12001 gtgttaattg atattcctta ttggttgaaa caacaagggc ttgatattct tgagagaact
    12061 aaaagtattt ttaatgctta gttatgcata cgtattctaa aacaaagggg gatataaagt
    12121 ggcatctacc aacaaaaata atgtaacaag taaagaggaa gaaaaagaag tttctacaag
    12181 tgggcttgaa tcatgtacgg ttaaagaaaa caaagctaaa atgaatcaaa ctaattttag
    12241 taatataaat gaaaatcaaa caaatgagaa taaaacgaac acatataaag gaaatataga
    12301 taaaataaac acaaataaat ccgacataaa taaagttaac atagatacag tggatacaga
    12361 taaattaaat acaaatactc ttactgaaaa aaataaaaaa gttatattta agggggaaga
    12421 taatatgtca tctacaaaaa tttactatgg agattcatta gaagtaacgc ctgttggagt
    12481 aatggattac aatgattttt caaaacagac aaaaagggaa caggaaatac ctggatttga
    12541 ttctaagtat agagattttg tagattatat tatgaagatt acacataata tctgggaaga
    12601 aaaaggtata ggtgttattt atgatacata tcacaataat gttacaatgc attgtggctc
    12661 ttcaaattta gttggtatta aagatgttat ttccaatact cttcaaacat tacatgcgtt
    12721 tcctgataga agattaattg gtcaaaatgt aatatggtct aactttggtg ctgatggttt
    12781 tttatcttct caccgtgttt tgtctacagc aactaactta ggtgatagta attttggacc
    12841 agcaacaggt agaaaaataa actttagaac tgtaattgat tgtgccacaa ctaacaatag
    12901 aatccacgaa gaatggttgg ttagagataa tttatggatt gttactcaat taggattaaa
    12961 ccctcaggaa gtagcaaaga gtatggcaaa ggcaagtgaa tctaaagtgc ttagcttaca
    13021 atcaacttat ggtatctgtg aatctatgga tggtcaattt atgccaacta agtatcaagc
    13081 aaaagatgat tctgttggcg aaatgatgct tgaaatgaca agccgtattt ataattataa
    13141 atatataaat gaagttaaaa aatactatca tgataatgca gtagtacatt ttatatgtga
    13201 taaagattta aatggttatg atgagattca aggaatgatt gtaagtttac ttgcatcaat
    13261 tccaaatgga agttatgaag tggaaagagt aacttgtaat caaagagaaa aaaatgaagg
    13321 ttatgatgta tctataagat ggagattacg tggaataaat gaaggtatag gattttttgg
    13381 acagccttct ggaaagcata tagaagtaat gggaatcaat cattatcata tacttcaagg
    13441 taaagtaaag gaagagtgga taacttttga tggtatggat gtattaaaac aaatgtatat
    13501 gggagtagaa gaataaagct gtttagagta taaataattt tgaaatgtat atagggaagt
    13561 attgctttat aaaatttaag tggggaatgt atatgaaaaa tagatgttta aacttttagc
    13621 aaaaattatg actaaattta aaagggggaa ttataaaaat atgaaaacaa cggttgaaat
    13681 agaaaatgat atcatattag gaaaagacta ttcaaaccta aaaagaggaa ttgcattttt
    13741 ttcaattgct ttaatatact ttttttattg ctacaatttt atggtgggta cttttattaa
    13801 accaacaatg atttatgctt tagcagatgg gggatttggc ttttcattaa aacaaacaga
    13861 agaaatattt gcagttatgt cttttggtac aattccaggt acatttattt ttggggtgat
    13921 ttctacaaaa attgggaaga agaggacttt aattagcgtt gctttactga ttggattgac
    13981 aacatttata ccaatgttat ctcctacaga tattatgtta tggaaaatag cacgtttgtg
    14041 tacaggagta gtgttgggag gcgtatttgg aacagctatg cctttagttg cagatatgtt
    14101 tccaagtaaa tatcgtggta agttagctgc tatattaact gctttatttt cattagcaat
    14161 gatttttggt gggaaagtat atggcgtttt aggtgatgca aattggcaaa tattgatgta
    14221 tactgcgatt ataccaccta tagttggagc tatcttagca atcttctttg tgccagatga
    14281 tttggagtat acaaaggaat tagttaaaaa gggaaaagaa actggtgaaa agattagcta
    14341 tataagtatg tataagggaa aatacttatg gattggattg ggaacgattc ttttatcagg
    14401 tgcaaatttt acagcatatt cagcattttc aaataatgca actacatacc tagtgacagg
    14461 aataggaatg tcagcagcag tggctgggtc tatatatagt ttacaaggaa ttggtcaatt
    14521 agtaggatat ttattctggg gttcaattgc agataaattt ggaagaaaaa taccttttat
    14581 aggtatggca ttagcagcag tatttgtttt tatatataca aaattaggtg gagataatac
    14641 aacaacattc tatatgatat cagtattact aggtgttgct gttggatatt ctggagcatg
    14701 gggagcatac tacacagagt tgtttccaag taaatatcgt tcgttgtcat ctggtatgtc
    14761 atttaatgga ggaaggatta tatctacgtt tgcaatacct gctatagctg gtacagcttc
    14821 tggtacttta ggtatgatga ctatctttta catatcaatc gcagtctttg tagcaggtgc
    14881 tattgtatgg ttattcttac cagagacgtt aaataataaa aaataaaata ctaggaattt
    14941 attttgttac ttagaaaggg gtggcttatg atttcatcaa ttgatgtatg tattataata
    15001 ggatatttgc tattaatgtt agttattggt tattattcag gaaaagataa taaaaatcaa
    15061 gaagattatt tcttggcagg taggtcaatg ccatggattc caattgcttt atcagttgca
    15121 gctactatga ttagtgcaaa tggctttata ggtggtcctg gatgggcata tgtagatgga
    15181 atgtatccag taatgtaaaa tgtgcaaaaa attcttttgt agttagtgca tttgttatga
    15241 atttagttta ctactttatg ctattggtag gagtaatttt atttgttttt tatgggggaa
    15301 ggacatttga aacttcaaat gaaataatga ttacttttat tttaaatgaa cttccagtag
    15361 gagccattgg aattattatt gcaggtgtgt ttgcagcagc aatgtctagt atcgactcta
    15421 tattaaacag tatgacaact gtttttacga aggatattta tgagttttat ttcaaaaaag
    15481 acaacaaaga atcatcatta aaagttacaa tgattataac tgtagttata ggagttgtta
    15541 tgacaggttt tattattatg ggatttggag gaagcatcaa atcaattctt gaccttgttg
    15601 gtaactatat ctcatacttt gctggaccag ctacaggtgc atttgtacta gcaatgttta
    15661 catataaagc taatgataaa ggagtatcta ttggttttat tgtagggtta gttttaggat
    15721 tttttatttc taataaatat aatgtgagtt ggttgtggaa tccagcaata ggtgctacaa
    15781 taacattgat atttggatat atttttagtg tcattttaaa gaaaaatcat aaagtagatg
    15841 atattaaaaa atacactgca tttggtatga gaaatcacct tatttctcaa ggaatggata
    15901 aagtagatgg agtatctata gtgccatttt ctttaggtaa acaagaacta attgtattag
    15961 ctttttttat tatccaatat attatattat ttttgataca attttaagaa gaaatactag
    16021 atatttaagg agaaatacta aatgaatcaa aagaaagttc attataataa atcggctaca
    16081 tcaaaagatg tcgcaagatt ggcaggagta tctcaatcat ctgtttcaag agcatttggt
    16141 agtgcaaatg gaaagggcgt aaaacctgaa gtaagagaaa gaatttttcg tgtagcaaac
    16201 gaaatagggt atgttcctaa tttggtagca cggggaatga ttagtggaaa aactaatgtt
    16261 ataggtttga tagttggtga tagtctaggt ccattttaca atagaattat caatttattt
    16321 gtagaaaaaa ttcaagagat aggtaaacag tgtctcgttt ttaaagttcc tagacaacaa
    16381 agtatagata gtataatttc aaaagtaatt cagtttcaag tagaagctgt gattattaca
    16441 gcttcggcca tgaataaggt gatggctgag acttgtgaag aaaacaatat tcctgtgatt
    16501 ctttttaatc gttttatacc tggtataaaa ataagtacag tctatgtaga cccaattgaa
    16561 ggtgggggca tggttgctga atatctgctt aagaaaggtc ataagaatat aggatatatt
    16621 caatttacga gagaaacaag tgaagaaatg gaaaagaaaa ttggatttta ttctaagtta
    16681 agacaaagtg ggattcataa ccttaaagaa gaatctgcaa actatgatta tgattctgga
    16741 tatgaagcag gtaagagaat gttagcatta tcaaatcctc caacagcaat tttttgcaca
    16801 agtgacttga tagctattgg tgtaatggat gctgcaaggt ttgagtacaa gttgagggtg
    16861 ccagaggatt tatcagtgat aggatatgat gatattcaaa tggcttcatg gaagagttat
    16921 aatttaacga cgattagaca accactagat ttgttgattg aaaaaacaat taacatactt
    16981 aagtccttat taaatgaaga aaatccagag tcagtcgttg aaatgttaaa acctgaattg
    17041 attgaaagag gttctacact ttaagtg
//
LOCUS       DAMJWO010000089        15959 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.092, whole genome shotgun sequence.
ACCESSION   DAMJWO010000089 DAMJWO010000000
VERSION     DAMJWO010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15959
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.092"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            235..384
                     /gene="rpmG"
                     /locus_tag="PC366_003079"
     CDS             235..384
                     /gene="rpmG"
                     /locus_tag="PC366_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004402360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDF2578573.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            410..631
                     /gene="secE"
                     /locus_tag="PC366_003080"
     CDS             410..631
                     /gene="secE"
                     /locus_tag="PC366_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HDF2578574.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTS
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            651..1193
                     /gene="nusG"
                     /locus_tag="PC366_003081"
     CDS             651..1193
                     /gene="nusG"
                     /locus_tag="PC366_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination factor
                     NusG"
                     /protein_id="HDF2578575.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDVDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            1229..1654
                     /gene="rplK"
                     /locus_tag="PC366_003082"
     CDS             1229..1654
                     /gene="rplK"
                     /locus_tag="PC366_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HDF2578576.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            1724..2422
                     /gene="rplA"
                     /locus_tag="PC366_003083"
     CDS             1724..2422
                     /gene="rplA"
                     /locus_tag="PC366_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HDF2578577.1"
                     /translation="MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     misc_feature    2474..2602
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            2645..3151
                     /locus_tag="PC366_003084"
     CDS             2645..3151
                     /locus_tag="PC366_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HDF2578578.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     gene            3209..3574
                     /gene="rplL"
                     /locus_tag="PC366_003085"
     CDS             3209..3574
                     /gene="rplL"
                     /locus_tag="PC366_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HDF2578579.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            3966..4754
                     /locus_tag="PC366_003086"
     CDS             3966..4754
                     /locus_tag="PC366_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDF2578580.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEGKIDILVNNFGSTNPSLDKDL
                     VTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPEFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            5225..8941
                     /locus_tag="PC366_003087"
     CDS             5225..8941
                     /locus_tag="PC366_003087"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDF2578581.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGQSFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     VEATEDEDIENLEEFTEDDLFEEEIDFESDDFDM"
     gene            8983..12468
                     /gene="rpoC"
                     /locus_tag="PC366_003088"
     CDS             8983..12468
                     /gene="rpoC"
                     /locus_tag="PC366_003088"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HDF2578582.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVLVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            12757..13179
                     /gene="rpsL"
                     /locus_tag="PC366_003089"
     CDS             12757..13179
                     /gene="rpsL"
                     /locus_tag="PC366_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HDF2578583.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            13302..13772
                     /gene="rpsG"
                     /locus_tag="PC366_003090"
     CDS             13302..13772
                     /gene="rpsG"
                     /locus_tag="PC366_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HDF2578584.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            13821..15887
                     /gene="fusA"
                     /locus_tag="PC366_003091"
     CDS             13821..15887
                     /gene="fusA"
                     /locus_tag="PC366_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDF2578585.1"
                     /translation="MARKFPLEKTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFINKMDILGADFYNVISMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
BASE COUNT         6246 a         1985 c         3249 g         4479 t
ORIGIN      
        1 atggattaaa aggaataaca aaaagagggg ttaggctcct ctttttttaa catagaaata
       61 caaaaacatt gacacagcat aggattttgt gataacttat acaaggtaat gattatagga
      121 agttaataat atcttgaata ctgtagattt ttaataaata catattttaa agatattata
      181 ttcacatata ttaacaatat atattattgt attacaaagt tggaggtgta tcagatgaga
      241 gttaaagtaa ctttagcatg tacagagtgt aagcaaagaa actacaacac tactaagaat
      301 aagaaaaata atccagacag aatagaatta caaaaatatt gtagattctg taaaaagcat
      361 acaactcata aagaaacaaa atagtttttt ataaggatgt gagtatggaa tggctgccca
      421 aaaaaatgac ggtgcaaaaa ctaaaaaaag gtttagttta tttggatatt taaaagaaac
      481 taagcaagaa ttaaaaagag ttacatggcc gacaaaaaag gaactgttta aaaacacaag
      541 tatagtttta actgtagtta tttcatgcac tatattagta tggggtatag acactatatt
      601 atctggtgca ctagcgttat tactaaaata gacgaaaaga ggtaagttaa atgtcagaat
      661 tacaagaagc aagttggtat gtagttcata cctattcggg acatgaaaat aaagttaaag
      721 ctacaattga gaaagcagtt aaaacaagag gtatggaaga ctgcataaga caagtagttg
      781 ttccaacaga agaggtagtg gaaactacta aaactggaaa agaaaaaact agacaacgta
      841 aagtttatcc aagttatgtc ttggttaaaa tgataataac tgatgaatct tggtatgtag
      901 taagaaatac taagggagtt acaggtttcg ttggacctgg ttcaaaacca gtaccattaa
      961 gtgaagatga agtcaaagct atggggatag atacaacaga ccctaaagta gtaaatagcg
     1021 atgttgattt tgaaatagga gacacagtaa aagtatctca aggaccattt agtggacaaa
     1081 taggtaacat agaagaaatt gacttagaaa atagagaagt caaagtatgc ataaatgcat
     1141 ttggtaaaag gactctattt gtaatagagc ttgaaggtat agaaaaaatc taatactata
     1201 tagaaaaatc tgaggaggtg cgctcaaaat ggctaaaaaa gttataggtc aaataaaatt
     1261 acaaatacct gcaggaaagg ctactccagc gccaccagtt ggaccagcat taggacaaca
     1321 tggtgttaat ataatgggat tcacaaaaga atttaatgct aaaactgcag atcaagctgg
     1381 aatgataata ccagttgtta taactgtata tcaagataga tcattcagtt ttataacaaa
     1441 aactccacca gctgcagttt taattaaaaa agcattaaac ttaaaatcag gttctggaga
     1501 accaaacaaa aagaaagttg ctaaaatgac ttcagctcaa gtaagagaaa tagctgagtt
     1561 aaaaatgcct gacttaaatg ctgcatcagt agaagctgct atgagtatga tagctggtac
     1621 tgctagaagc atgggtgttg taatcgaaga ctaattaaaa gatacacttt ttttataaag
     1681 tgggaggcga gaagccgaaa ttaaccacaa ggaggaaaat aaaatggcta aaaaaggtaa
     1741 aagatatgca ggtgcattac aaaaagtaga tagaactaaa ttttatgatg catcagaagc
     1801 attaacatta gtttcagata tagctggagc taaatttgat gagacagtag aagcacacat
     1861 taaattaggt gttgactcaa gacatgctga ccaacaagta agaggtgcag ttgtattacc
     1921 tcatggaact ggtaaaacaa aaagagtttt agtttttgct aaaggtgaaa aagctaaaga
     1981 agctgaacaa gctggtgctg actttgtagg agctgaagaa ttagttcaaa aaatacaagg
     2041 tgaaaactgg tttgactttg atatagtagt tgctactcca gatatgatgg gtgtagtagg
     2101 tagattaggt agagtattag gacctaaagg tttaatgcca aaccctaaat caggaacagt
     2161 tacatttgat gtagctaaag ctatagatga aataaaagct ggtaaagttg aatacagatt
     2221 agacaaaact aacataatac acgttccagt aggaaaagta tcatttggtg gagaaaaatt
     2281 aactgaaaac tttactgcat taatggatgc tataataaaa gctaaaccag ctgctgctaa
     2341 aggacaatat ttaagaagta taacagtagc ttcttcaatg ggacctggag ttaaaataaa
     2401 cccagcaaga acagctgaat aataaaactg ttgacacagg ttgacaaaaa tgttattata
     2461 tcacttgtca atgtaaaaaa gaatagattt gccgtagata gtgggtgcga aagcttaata
     2521 tcccgccgag gttttagata aattgagatt actaaagctt ttgatgtcta cttttggcaa
     2581 caaaagcttt ttataatgtt gcggtaaata ttaagcctat ttggtgaagg aggtgcacat
     2641 ctatatgaga aaagctatag aaattaaatc agaagttgtt tctgagatag ttgaaaagtt
     2701 acaaaaatct tctgctgctg ttgttgtaga ttacaaagga ttaacagttg aagaagtaac
     2761 tgagttaaga aaacaaatga gagaagctgg tgtagattac aaagtataca aaaatacttt
     2821 agttagaaga gcagctaaag aagttggtat agagcaattt aatgatgaat tattagttgg
     2881 aactaatgcc atagcatttg gatatgatga tccagttgct ccagctagaa tattaaaagg
     2941 attcatggat tctcatccaa aaatgaaatt aaagatgggt attgtggaag gtgcattcta
     3001 tgatgaatct aagattgttg aaatggctaa cataccatca agagaagttc ttatcgctaa
     3061 attacttggt agcttaaaag ctccagtatc aaacttcgca tacttaatag atgcaatagc
     3121 gaaaaaggca gaaggtcaag aagaagctta attgcttaac taaaaaatta taaatattaa
     3181 tttgaaataa aattcggagg tgctaaaaat gacaatagaa caaatattag aagctataga
     3241 aaatatgaaa gttttagaat taaatgaatt agttaaagct gctgaagaaa aattcggtgt
     3301 atcagcttca gctccagtaa tggtagctgg tgcagctgct ggtggaccag ctgctgaaga
     3361 aaaaactgag tttgatgtag tattaactga cgttggttct tcaaaagttg gagttataaa
     3421 agcagttaga gaaataacag gattaggatt aaaagaagct aaagaagtag ttgacaatgc
     3481 tcctaagaca gttaaagaag gagcttctaa agaagaagct gatcaaataa aagagaaatt
     3541 agaagctgct ggagctaaag tagaagttaa gtagtttctt taaaaagata cccattgggt
     3601 atcttttttt atttataaaa aactataaag aaagtatttg gaattataaa gaaagtgttt
     3661 ttataaaata aaaaaaattt atataatagt actaaattaa gggtatcata tatggtgtaa
     3721 tggtatttta atttaacatt attatcaaat taaaatataa acaattgttg taatgtctgt
     3781 atataaagta tataattaaa ctaaaatgta aaattttaca ttttagttta aaaaaataca
     3841 cgagtgtttt ataaataaaa tgtaataaat aattaattaa caaatataaa ttttaaaata
     3901 agttagatat ttagaaaaat cgaaatttgt aggatttaaa ggacatattc aaggaggagt
     3961 taataatgga aaaattacaa ggaaaaattg cagtagttac tgcagcaaca aaaggtattg
     4021 gattagcatc agcagagata ttagcaaaaa atggagcaac tgtgtactta gcagctcgtt
     4081 cagaagaatt agctaatgaa gttataaata aaataagtgc agaaggtggt tgtgctaagt
     4141 ttgtttactt taatgctcgt gaagaagaga cctttacctc aatgatagaa gaggtagtta
     4201 aaaaagaagg taagatagat atacttgtaa acaattttgg ttcaacaaac ccttctcttg
     4261 acaaagacct tgtaactggg gatacagata atttctttga cacagtaaat actaatttaa
     4321 aaagtgtgta tttaccatgt aaagcagcaa ttcctcatat gataaagaat ggaaaaggaa
     4381 gtatagtaaa tatatcaagt ataggttcag tattacctga tttatctaga atagcttact
     4441 gtgtatcaaa agcagcaatc aactcattaa ctcaaaacat agctacacaa tatgctaaag
     4501 acaatgttag atgtaatgct gtacttccag ggcttattgc aactaaagca gcattagaca
     4561 atatgtctcc agagttcata aaagaatttt taaagcatgt tcctttaaat cgtatagggg
     4621 aaccagatga tatagcaaaa gctgttctat tctatgctag tgatgactca tcatttataa
     4681 caggggattt acttgaagtt gcaggaggat ttggtttacc tactccacaa tttgcagata
     4741 atatattagg ataattaaat tactaatatg caatgaaagc ttatgcatta gttatagtag
     4801 aaatgatatt tttataaagg ccatagatat aatttatatt ggaaaggttt gaggttcaaa
     4861 attccaagtt aaatttattt atggtcttta ttttgtatat tttaataaat tgtatatatt
     4921 tgtataaatg taattattta caatcatttt aatatggaat tataattaaa taggggggat
     4981 ggtacttgta taaaattttt tatagaaaat tagacctata aatgaaaaat atggatttta
     5041 tattggaaaa ttgtacataa tacataatat atgcttaaaa taatttacaa aaaatcaaaa
     5101 ataatgcata gtttacatat aagataaaaa atatattgaa aaatacttga cattatgcta
     5161 aaattattag atgcgttaga atgaactatt gttttatttt taattattga gaggtgaaaa
     5221 gtgaatgcca catcctgtca cgataggtaa aagaactaga atgagctttt ctaaaattaa
     5281 ggaaatagct gatgtgccaa atcttataga aattcaagta gattcctatg agtggttttt
     5341 aaaagaaggt ttaaaagaag tgtttgatga tatttcacca atagaagatt atactggtaa
     5401 tcttatattg gaatttgtcg actattctct agatgataaa ccaaagtacg atatagaaga
     5461 gtgtaaagag agagatgcta catattgtgc acctctaaag gttaaggtaa gacttataaa
     5521 taaagaaaca ggtgagataa aagaacaaga agtgtttatg ggtgacttcc ctttaatgac
     5581 agaaagagga actttcgtta taaatggagc agaaagagtt atagtaagtc aattagttag
     5641 atctcctggt gtttactatg cggaagaaag agataaaaca ggtaagagat tgatttcatc
     5701 tactgtaatt cctaatagag gagcatggtt agaatatgaa acagattcta atgatgtaat
     5761 atctgtaaga gttgatagaa caagaaaaca accagttaca gttttactta gagctttagg
     5821 aataggaaca gatgcagaga taattgacct tttaggagaa gatgagagat tatctgctac
     5881 attagaaaaa gataatacta agacagtaga agaaggtctt gtagagatat acaaaaaatt
     5941 aagaccaggt gaacctccta ctgtagaaag tgcatcatct ttattaaatg ctttattctt
     6001 tgacccaaaa agatatgacc tagcaaaagt tggtagatat aaattcaata agaaacttgc
     6061 tttatgttat agaataatga ataaaatttc agcagaagac ataataaatc cagaaactgg
     6121 agaagtattt gtaaaagctg gagaaaaaat aagctatgat ttggctaaag ccatacaaaa
     6181 tgcaggtata aatgtagtaa atctactaat ggatgatgat aaaaaagtta gagttatagg
     6241 aaataatttt gtggatatta agtctcacat tgattttgac atagatgatt taaacataaa
     6301 agaaaaagta cattatccaa ctttaaaaga aattttagat ggatatagtg atgaagaaga
     6361 aataaaagag gctataaaat caagaattaa agaacttata ccaaaacata tattattaga
     6421 tgatataata gcttcaataa gttatgagtt caatatattc tataatatag gaaatattga
     6481 tgatatagat cacctaggaa acagaagaat aagatctgta ggtgaattgt tacaaaatca
     6541 agttagaatt ggtctttcaa gaatggaaag agttataaaa gaaagaatga cggttcaaga
     6601 tatggaagct ataacgcctc aagcgttagt taacataaga ccagtttcag ctgcaataaa
     6661 agaatttttt ggtagttctc agttatctca gttcatggat caaacaaatc ctctatctga
     6721 gttaacgcat aagagaagat tatcagccct tgggcctgga ggtctttcaa gagaaagagc
     6781 tggattcgaa gtgcgtgacg ttcaccattc acactatggt agaatgtgtc caatagagac
     6841 tccagaggga ccaaatatcg gtcttataaa ctctctagga acttatgcaa aaataaatga
     6901 atttggattt atagaatcac catatagaaa atttgataaa gaaacatcaa cagttactga
     6961 tgaaatacat tatttaactg ctgacgaaga agatttattc gtaagagctc aggcaaatga
     7021 gccattaaca gaagatggta aattcgtaaa ccatagagtt gtttgtagaa ctgtaaatgg
     7081 tgctgttgaa atggttcctg aaagtagagt agattacatg gatatatctc ctaagcaggt
     7141 tgtatctgtt gccactgcta tgataccttt cttagaaaat gatgatgcca accgtgccct
     7201 tatgggagcg aacatgcagc gtcaggcagt gcctctagtt agaagagaag caccaattat
     7261 aggaactggt atagaataca gagcagcaaa agactctgga gcagttgttg ttgctagaaa
     7321 ttctggtata gcagaaagag taacagcaga tgaaataatt ataaaaagag aagatggaaa
     7381 cagagataga tataatctac ttaagtttaa acgttcaaac tcaggtactt gtataaatca
     7441 aacacctata ataaataagg gtgaccagat aataaaaggt gatgttatag cagatggtcc
     7501 agcaactgat ttaggagaag ttgcacttgg aagaaactgt cttatagcat tcatgacttg
     7561 ggaaggttat aactacgagg atgctatatt aataaatgaa agattagtta aagaagatag
     7621 attatcaaca attcatatag aagaatatga atgtgaagct agagatacaa aactagggcc
     7681 agaggaaata actagagata tacctaatgt tggagatagt gcaatcaaaa acttagatga
     7741 tagaggtata ataagaatag gtgcagaagt agactcaggt gatatattag ttggtaaggt
     7801 aactccaaaa ggagaaactg aacttactgc tgaggaaaga ttacttcgtg cgatattcgg
     7861 agaaaaagcc agggaagtta gagatacttc acttaaagta cctcatggtg aatctggtat
     7921 aatagttgat gtaaaagtat ttactagaga aaatggagat gatttatctc caggagtaaa
     7981 tgaattagta agatgttata tagctaaaaa gagaaagata aaagttggag ataagatggc
     8041 tggtcgtcat ggtaataaag gggttatctc gagagtatta cctgaagaag atatgccatt
     8101 catggaaaat ggaacgccat tagatataat acttaaccca caaggtatac catcacgtat
     8161 gaacatcggt caggttctag aagttcattt aggacttgct gctaagacat taggatggta
     8221 tgtagcaaca tcagtattcg atggtgctaa tgagtatgac ataatggatg ctcttgaaga
     8281 agctggatat cctagagatg gtaaattaac tttatatgat ggtagaacag gtcaatcttt
     8341 tgacaataga ataactgttg gatatatgta ttacttgaaa ctacatcact tagtagatga
     8401 aaaactacat gcaagaagta ctggaccata ctcattagtt actcaacagc cactaggtgg
     8461 taaagcacaa tttggtggac aaagatttgg agagatggag gtttgggctc tagaagcata
     8521 tggagcggct cacatacttc aagagatact tactgttaag tctgatgatg ttgtaggtcg
     8581 tgttagaact tatgaagcta tagttaaagg tgaaaacata cctgagccag gaatcccaga
     8641 atcatttaag gttcttataa aggaacttca aagtttatgc ttagatgtaa aagtattgac
     8701 agatgaagac caagaaatag aagtaagaga atctgtagat gaagatgata cgataggtga
     8761 atttgagcta gacgttgtaa atcacatggg agaagttgaa gaaagtaata taatagaaga
     8821 aattgaagat gattttgtgg aagccacaga agatgaggat atagagaatt tagaagaatt
     8881 cactgaagat gatttatttg aagaagaaat agattttgaa agtgatgact ttgatatgta
     8941 aatttaatta atgtaaatct caaatagaag ggagagaact ccttgtttga attaaacaat
     9001 ttcgagtcga taaaaatagc attggcttct ccagaaaaaa taagacaatg gtctagagga
     9061 gaagttaaaa agccagaaac tataaattac cgtactttaa agccagaaaa agatggtctt
     9121 ttctgtgaaa ggatatttgg accacaaaaa gactgggagt gtcattgtgg taaatataga
     9181 agagttagat ataaaggtgt agtttgtgat agatgtggag tagaagtaac taaatcaaaa
     9241 gtaagaagag agagaatggg acatatagag ctagctgctc ctatgtctca catctggtac
     9301 ttcaaaggta taccaagtag aatgggactt ttacttgata tgtcaccaag atcgttagaa
     9361 aaaatactat atttcgcctc atatgtagta gttgatccag gtgaaactgg attgaatgaa
     9421 aaacagttac ttacagaaaa agaatacaga actgctcttg aaaagtatgg atatactttt
     9481 actgtgggta tgggtgctga agctgtaaaa acattactac aaaatataga tttagaacaa
     9541 caaagtaaag acttaagagc ggaattaaaa gatagtacag gacaaaagaa agtaagaaca
     9601 attagaagat tagaagttgt agaagcattt aaaaaatctg gaaataaacc agaatggatg
     9661 attttagatg caataccagt aataccgcca gatttaagac caatggtaca acttgatggt
     9721 ggaagatttg caacttcaga cctaaatgat ttatacagaa gagttataaa tagaaataat
     9781 agacttaaaa gactattaga gcttggagct ccagatataa ttgtaagaaa tgaaaaaaga
     9841 atgcttcaag aagctgttga tgcattgata gataatggta gaagaggtag acctgtaaca
     9901 ggacctggaa atagaccact taaatcttta tcagatatgt taaaaggtaa gcaaggtcgt
     9961 ttccgtcaaa acttacttgg taagcgtgtt gactactcag gacgttctgt tatagttgtt
    10021 ggaccagaac ttaaatttta tcaatgtgga cttccaaaga agatggcatt agaattattc
    10081 aagccatttg ttatggataa attagttaaa gaaggttatg cacataatat aaaaagtgcg
    10141 aaatctatag tagaaaaagt taagccagaa gtttgggatg ttttagaaga tgttataaaa
    10201 agtcatccag ttcttcttaa ccgtgcaccg actctacata gattaggtat acaagcattt
    10261 gaaccaatct tagttgaagg taaggctata aaactacatc ctcttgtatg tacagcttat
    10321 aatgcagact ttgatggtga ccaaatggca gtccatgtac ctttatcagt agaagcacaa
    10381 gcagaagcaa gattcttaat gctttctgta aataatatac ttgctcctaa agatggttca
    10441 cctataacta ctccatctca ggatatggtt ttaggttgct attatctaac aatagaagcc
    10501 caagatggag ctaaaggaac aggtatggta tttaaagact ttaatgaact attacttgct
    10561 tattacaata aatcagttca tctacatgca ttagtgaaac tgaaggtaac acttgaagat
    10621 ggaagaagtt cattggttga aagtactgtt ggtagattta tatttaatga aaatatacct
    10681 caagacttag gttttgtaga tagaaaagaa aatccatttg cacttgaagt tgatttctta
    10741 gcagataaaa aatctcttgg taaaataata gataaatgct ttagaaaaca cggaaataca
    10801 gaaacagctg aattactaga ttatataaaa gctctaggat ttaaatattc tacattaggt
    10861 ggtataacag ttgctgttga tgatatgagt gtcccagaag aaaagaaagt atttatagct
    10921 gaggcagaag ctaaagttga taagtatgaa aaagcataca gaagaggtct aatctctgat
    10981 gaagaaagat atgaaaaagt tatagagaca tggacagaaa caactgataa agttactgat
    11041 gctcttatgg gtggactaga tagattaaat aatatatata taatggcaca ttcaggagcc
    11101 agaggttcta aaaaccaaat tagacagctg gcaggtatgc gtggtcttat ggcaaatgca
    11161 tctggtaaaa cagtcgagat accagttaaa tctaatttcc gtgaaggttt atcagtacta
    11221 gaatacttta catcttcaca tggtgccaga aaaggtcttg ccgatacagc tatacgtaca
    11281 gctgaatctg gatatttaac aagaagactt gttgatgtaa gtcaagatgt tattgtaagg
    11341 gaaatagatt gtggaacaga agatactaca gagatttatg ctataaaaga aggaaatgaa
    11401 gttatagaag agatatatga tagaattgta ggaagatata ctatagaccc tatattaaat
    11461 cctgaaactg gagaagttct agttgaggct gattcaatga tacaagaaga tgaagcagaa
    11521 actatagtag ctttagggat tgaaaaaatt aggataagaa cagttcttaa ctgtaaaact
    11581 aatcatggag tttgttctaa gtgttatggt agaaacttgg caacaggaaa agaagttaat
    11641 ataggtgaag cagttggtat aatagcagct caatctatcg gtgagccggg tactcagctt
    11701 acaatgcgta cattccatac tggaggagtt gcaggagctg atataactca aggtctacca
    11761 agggttgaag aattatttga agctagaaaa ccaaaaggat tagctgtaat aactgaagta
    11821 tctggtagag ttgaaattga tgaaacagga aagagaaaag aagtaaatgt aataccagaa
    11881 gaaggcgaga ctcaaacata tgtaattcca tatggttcta gattaaaagt taagcaaggt
    11941 caaatgctag aggctggaga ccctctaaca caaggattta taaatcctca tgatatagta
    12001 agagtaaatg gtgttaaggg agttcaagaa tatatagtta aagaagttca aagagtgtat
    12061 agacttcaag gggttgatgt taatgataag catatagaag ttatagtaag acaaatgcta
    12121 tctaaagtaa aagttgaaga cccaggagat acagatttat tgccaggtgg atatgaagat
    12181 gtattaacat tcaatgaatg taataaagat gctatagata aaggtctaag accagcagtt
    12241 gctaaaagag ttttacttgg tataactaaa gcatctcttg caactgattc attcttatca
    12301 gcagcttctt tccaagaaac aacaagagta ttaacagagg cagcaataaa aggtaaagaa
    12361 gaccacttaa taggacttaa agaaaatgtt atattaggta agttaatacc agcaggaaca
    12421 ggaatgaaga aatatagaaa tatagctgtt gaaaaaattg aagattaata gcatatagag
    12481 taaagaaatc ttgacaacca ttatttgtgg tgttaaaata gtaaagtgtg ttgtttaaaa
    12541 gtacactaag ggcttgaaca agttcttagt gacttttaga tggcaataaa tgagaactaa
    12601 aaagcatcaa gctagaaaag tgctaatatc acatatttat gtgttataga cattaaattg
    12661 taagtaacga atgttacaat cagtcagtat gaatattcat attgatgtag ttggcggtca
    12721 ctgataagat cgaaaatttg gaaggaggtg cagatgatgc caacaattaa ccaattagtt
    12781 cgtaaaagta gaaaagcgct agagaagaaa tctactgctc cagcattaca aaaaggttac
    12841 aactctttaa ataagaaagt aactgacgct agtgccccac aaaaaagagg ggtttgtact
    12901 tcagtaaaaa cagttactcc taagaagcct aactcagctt taagaaaagt tgccagagtt
    12961 agattaacta atggtataga agtttctgct tatataccag gagaaggaca caacttacaa
    13021 gagcatagtg ttgttcttat aagaggagga agagtaaaag accttccagg ggttagatac
    13081 catatactaa gaggtactct agatacagca ggtgttgata agagaagaca atcaagatct
    13141 aaatacggtg cgaagagacc taaagaagct aaaaaataaa acaattaatg attgattata
    13201 gttcggtgct ttaaatatat atatatttac ggcatcacgg cattaaatga tttatgtcga
    13261 gtacctatga tttaagttaa ataattaagg agggaagcga aatgccaaga aaaggtaata
    13321 ttccaaaaag agaagtttta ccagatccta tgtatgggag taaggtagtt actaaattaa
    13381 taaataatct aatggtagac ggaaaaaaag gaaagtctca aagaatagtt tatgatgctt
    13441 tcgcaattgt tgctgaaaag acaggagaag aagctttaga agtatttaat aaagcaatgg
    13501 ataatataat gcctgtttta gaagtaaaag caagaagagt tggtggggca aattaccaag
    13561 tgccaatcga agttagacct gaaagaagac aaacattagg tttaagatgg ctagtaaaat
    13621 atactagagc tcgtggagaa aaaggaatgg ttgaaaagct agctaaagag ataatggacg
    13681 cagctaacaa cactggagct tcagttaaga aaaaagaaga tactcataaa atggcagaag
    13741 ctaataaagc atttgctcat tacagatggt aggatatata gatatcttat aaattcaagg
    13801 atatcataag gaggataacc atggctagaa agtttccttt ggaaaaaact aggaatatag
    13861 gaatcatggc tcatatagat gcaggaaaga ctactactac agaaagaatc ctgttttata
    13921 ctgggcaaac tcataaaata ggagaaactc atgaaggagc ttctcaaatg gactggatgg
    13981 agcaagaaaa ggaaagaggt ataacaataa cttctgccgc tactactgct tcatggaaag
    14041 accatagaat aaacataata gatactcctg gacacgtgga cttcacagtt gaggttgaaa
    14101 gatctctaag agttcttgat ggttcagttg ctgtattctg tgcaaaaggt ggggttgagc
    14161 ctcaatctga aaatgtatgg agacaagctg aaacttatgg agtacctaga atagctttta
    14221 taaacaaaat ggatatatta ggtgcagatt tctacaatgt tataagcatg atgaaatcta
    14281 gattaaattc taatgcagtt cctatgcaat taccaatagg taaagaagat tcatttatag
    14341 gtataataga cttattaaaa atggatgctg ttatatacaa agacgaccta ggggttgaaa
    14401 tggaagaaac agatatacca gaagatatga aagaattagc tgctgagtgg agagaaaaat
    14461 tagttgaatc agtagctgaa actgatgaag aattaatgat gaaatacctt gaaggtgaag
    14521 aacttactat agatgaatta aaagttgcta taagaaaagc tactatagct tgtgaaatga
    14581 acccagtttt ctgtggtaca gcttatagaa acaaaggtgt tcagttagta atagatgcag
    14641 ttttagatta cttaccagca ccaactgata taccagctat aaaaggtata ttagcagatg
    14701 gagaagaagc tgaaagacat tcttctgatg aagagccatt ctctgcatta gcattcaaaa
    14761 taatgactga cccattcgtt ggaaaactag cgttcttcag agtttattct ggaacattag
    14821 aatcaggttc ttatgtttta aatgcaacta agaataagag agaaagaatt ggtcgtatat
    14881 tacaaatgca tgctaataca agagaagaaa taactaaagt gtatgctgga gatatagcag
    14941 cagcagtagg attaaaagat actactactg gagacacatt atgtgaccct gctaatccaa
    15001 taatacttga atctatggaa ttccctgagc cagttatatc tgttgctata gaaccaagtt
    15061 ctaaagcagc tcaagaaaaa atgggtatag ctcttcaaaa attagctgaa gaagacccaa
    15121 ctttcacagt taagactgac caagaaacag gacaaactat aatatctggt atgggtgaat
    15181 tacacttaga gataatagta gatagattat taagagaatt taaagtagaa gctaaagttg
    15241 gtgcaccaca agttgcatat agagagacta taactcaacc agttgatgtt gaatacaagt
    15301 actctaagca atcaggtggt agaggacaat acggtcacgt taagattaga gttgctcctc
    15361 aagagccagg tgaaggatac aagttcacaa acaaaactgt tggtggatca gtaccaaaag
    15421 aatatgttgg tccagttgac atgggtatac aaggagctat gcaatctggt atagttgctg
    15481 gatatccagt tgtagacgtt gctgttgagt tatatgatgg ttcttaccat gaggttgact
    15541 cttctgagat ggcgtttaag atggctggtt caatggcatt caaagatgct atgaagaaag
    15601 gtaatgcagt tcttttagag ccttacttca aagtagaagt tgttactcca gaagattaca
    15661 tgggagatgt tatgggtgac ttaaactcaa gaagaggatt aatccaaggt atggaagcta
    15721 gaagtggtgc acaagttata aatgcattcg ttccactttc agaaatgttt ggatactcaa
    15781 cagacctaag atcttcaact caaggtcgtg caacttacac aatgatattc gatcactatg
    15841 agcaagttcc agcttcagtt gctaagaaaa tagctgaagg aaaataattt aaaaataatt
    15901 aataatataa atataaaaaa taatcagcta gatgagatat atctcatcta gcacaagat
//
LOCUS       DAMJWO010000090        15530 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.093, whole genome shotgun sequence.
ACCESSION   DAMJWO010000090 DAMJWO010000000
VERSION     DAMJWO010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15530
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.093"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(131..865)
                     /locus_tag="PC366_003092"
     CDS             complement(131..865)
                     /locus_tag="PC366_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine biosynthesis protein TtcA"
                     /protein_id="HDF2578586.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMIYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
     gene            991..1707
                     /locus_tag="PC366_003093"
     CDS             991..1707
                     /locus_tag="PC366_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2578587.1"
                     /translation="MKKFKLIGAIILVVFISVFISKDRLLKKDKDPIVAAQHDSEQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            1841..2533
                     /locus_tag="PC366_003094"
     CDS             1841..2533
                     /locus_tag="PC366_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2578588.1"
                     /translation="MNNTVLVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMILDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIKVGVVIIDKEKHSVTVAGNEIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            2523..3704
                     /locus_tag="PC366_003095"
     CDS             2523..3704
                     /locus_tag="PC366_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HDF2578589.1"
                     /translation="MKNKSLLNHMFRPILDLIISCALTSMLILTSMYIIKLLYFNSEI
                     SVINQLVYQLRDFRSLIGESLFYPFLFTITSLAIYSMISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDKEKDDIDELAHKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVVSQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGHYVDIVTEKMEDMAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHDGEITVSSDKYQTVFEVQLPIIQS
                     A"
     gene            3986..4441
                     /locus_tag="PC366_003096"
     CDS             3986..4441
                     /locus_tag="PC366_003096"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HDF2578590.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            4431..5156
                     /locus_tag="PC366_003097"
     CDS             4431..5156
                     /locus_tag="PC366_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vitamin B12 dependent methionine synthase,
                     activation domain protein"
                     /protein_id="HDF2578591.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKYTIDECVAIT
                     KNKINPRYLSRIYPIRINKDNVVELEGTNLTLESKDVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSNLTKGLIIDSCGTTAIEEVCDIVQNNLEKVFLNQDKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISNTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            5128..7509
                     /locus_tag="PC366_003098"
     CDS             5128..7509
                     /locus_tag="PC366_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HDF2578592.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDNAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVQSPTVVGERLNPTGRKSLQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVNRAVSCGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKSDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDEI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(7714..8943)
                     /locus_tag="PC366_003099"
     CDS             complement(7714..8943)
                     /locus_tag="PC366_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDF2578593.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWSIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPKGHVWLSGASKDPNGISFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGNWAF"
     gene            9543..10457
                     /locus_tag="PC366_003100"
     CDS             9543..10457
                     /locus_tag="PC366_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578594.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKNFEEDEEDDLDYLAGVKTEEDDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKRPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEETQEENVTLEKEESQDE"
     gene            10481..11116
                     /locus_tag="PC366_003101"
     CDS             10481..11116
                     /locus_tag="PC366_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HDF2578595.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     RKIAYNAGLVEAEGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTAQKIFEHH
                     GFEVFSVICKNGAMPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEAKVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            11492..12208
                     /gene="pyrF"
                     /locus_tag="PC366_003102"
     CDS             11492..12208
                     /gene="pyrF"
                     /locus_tag="PC366_003102"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HDF2578596.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDRLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVRAAVRDNVWLMTIHVSDMEGMRQCAL
                     IAREEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGADFITVCPGIRPKSAEVGDQKRVVTPSDAIKKGAHYLVVGRPI
                     TKAENPRESAINIVREIENA"
     gene            12234..13277
                     /gene="carA"
                     /locus_tag="PC366_003103"
     CDS             12234..13277
                     /gene="carA"
                     /locus_tag="PC366_003103"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDF2578597.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKEAIGEVVFNTSMAGYGEILTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     IENIKGTGAKVVVIDFGVKNSVLESLKACNCDITIAPAMTTVEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            13330..>15530
                     /gene="carB"
                     /locus_tag="PC366_003104"
     CDS             13330..>15530
                     /gene="carB"
                     /locus_tag="PC366_003104"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) large subunit"
                     /protein_id="HDF2578598.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEVADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIADNEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVANELGYPVLVRPSYVLGGQGMEITYNEEKLSQYL"
BASE COUNT         6253 a         1715 c         2794 g         4768 t
ORIGIN      
        1 tattaagaac tattaaaata tagattaaag ataataacat ataataaata aaaaagtaag
       61 attgtgtaga ttatataaag attatttata attaatacaa tcttgctttt ttatttaaaa
      121 attttaatta ttatttaaaa ttttttatct tctctttatc ccatataaac aatttctcag
      181 aattatttaa agcgccaaat acatttcttt taaaatcagg catctcttta tttaaattag
      241 caataagatt ttttatgtac tctctcctag tatgaccatt tgcagggcag ggatttgtga
      301 taataggata gttagaatct tttgaaattt tcttagtcat atactcttct atgtaaatca
      361 taggtcttat aactgttaaa tcctgtctat ctaggtatgt ctttggggaa aaacaattta
      421 ctctaccctc ataaaacata gacattaaaa atgtctcaat tgcatcatct ttatgatgac
      481 caagagctac tttattacat ccaagttttt tagcattatc gttcaaagca cctcttctta
      541 aattagcaca taatgcacaa ggattttttt cttgtcttat atcaaataca atttctttta
      601 tgtcagtttg aaattcataa aaaggaacat ttatttcttt acacaattta tctagtggag
      661 aattatcaac acctccagta tttaatgtta tggctatcaa ttcaaagttt tgtggagaaa
      721 atctttgata acttttaagt atatgaagta gagttaaact atcttttcca ccagaaagtc
      781 caaccgcaat tttatcattt tcttgtatca tatcaaaatc ttgtatagcc ttacgagctt
      841 tacttagaag tttttgtata gacattttat caccatcctt taaaaatatt aaatttaaga
      901 tttatttaag atttacttat aaaatactta agtcttatac tctaaaatta acattataga
      961 caaacataac aaaaaggaga agatttaatt atgaaaaaat ttaaattaat aggagccatt
     1021 attttagtag tatttataag tgtatttata tctaaagata gattacttaa gaaagataaa
     1081 gatccaatag tagctgctca acatgattca gaacaagatg ttgaggcaaa ttctcaaaat
     1141 aaaaatcact caaatagtat atcaaatata ttattggtaa acaagacaaa tggaattagc
     1201 aaaaactata ctcctgaaaa tattactaag gtaaacatac cttttgttga agaagcaaca
     1261 gaggaagaaa aacaaatggc aggagaacct gcaaaggcag ttgaagattt agttaagcaa
     1321 gctaattcag aaggaataca gtttttaggg tcttcagcat acagatctta tgatactcaa
     1381 ctggatactt atacaagaag ggtaaaatct cagggacgag aaaaggcaga tgcatatgta
     1441 gcaaagcctg gttacagtga gcaccaaact ggactttgta ttgatttaac aaatccagaa
     1501 agatggtttg ttggaagtac aaaagaagct aaatggttgg cagaaaatgc tcacaagttt
     1561 ggatttataa taagatatcc tgaaggtaaa gaagatataa caggtacagc atatgaacca
     1621 tggcatatta gatatgttgg taaggatgct gccgaggaaa tttattcaaa aggattaact
     1681 ttagaagaat atttacaaaa taaataatat aaatgtgtaa ataatttgta ttatattgga
     1741 aatttagaaa tgaataaatt tatagattac actaactaaa atatagtata attttatatg
     1801 aataaagcta tatacaaaga ttaagttagg atgtgtaaaa atgaataata cagttcttgt
     1861 tgtggatgat gaaaaggaaa taagagacct tatagagata tatcttttaa atagtggata
     1921 taatgtaatt aaagctgaag atggaaaaga ggctctagat attttaaaaa aggaaaatat
     1981 tcatttaatg atattggata taatgatgcc taaaatggat gggatagaag tttgtagaaa
     2041 agttagagaa agtttgaata taccaatact tatgttaagt gcaaaatcag aagatatgga
     2101 taaaatacaa gggataatga ctggtgcaga tgattatttg acaaaaccat ttaacccact
     2161 tgaacttact gtgagagtga aatcactgat tagaagagca tattatttta gtggtgctaa
     2221 taatgaagat aaagatgtca taaaggttgg agtagtaatt atagataagg aaaaacatag
     2281 tgtaacagtg gctggaaatg aaataatttt gacatcaaga gaatttgata tattatattt
     2341 actagcaaat aataaaggca gagtatatag tacagaagaa atatttgaaa aggtatggaa
     2401 agagaaatat taccaatcta ataatactgt aatggttcat atgagcagaa taagggataa
     2461 aattgaaaaa tatacagatg gagaaaaaat aattcatact gtatggggag taggatataa
     2521 aattgaaaaa taaaagttta ttaaatcata tgtttcgacc catattagat cttataataa
     2581 gctgtgcttt aacttcaatg cttattttaa caagtatgta tataataaaa ttattatatt
     2641 tcaatagtga gatatctgta attaatcaac ttgtatatca gttaagagat ttcagaagtc
     2701 ttataggaga gagtttattt tatccatttt tatttacaat cacatcatta gcaatttatt
     2761 ccatgatatc gtacaagaga aataagcaaa ttgtagattt tataagaaag actaatagaa
     2821 aaaatcaaaa attagaaatc attaaaagtg ctgtaaattt aatggatgaa ggtaacttag
     2881 aaaaaagtat agatattgag tatgatttag atatattaaa ggataaagaa aaggatgata
     2941 ttgatgaact agcacataaa atcaataata tagtccatca acttagaaat ataactattg
     3001 aagagagaca agctcagcag acaaaaacag atttaataac aaatgtgtca catgacttaa
     3061 gaacaccttt gacatccata atgggttatt taggagtgat agaagaaggt aagtataaag
     3121 atgaagttca gatgatgtat tatgttgata ttgcatatga aaaatcgaaa aatttaaatg
     3181 ttcttataaa tgatttgttc gaattgacta aaatgcaaaa taatacaata aaactaaaca
     3241 aaatagaaat aaatttagta gagttattaa gtcaagtagt atctcaattt gaaatttatt
     3301 ttaaacaaga atttatggtt agtagaatta attttaatga agaaaaatta attgtgaaag
     3361 ctgatccaaa taaattggta agagcatttg aaaatcttat aactaatgct gtgaaatatg
     3421 gaaaagatgg gcattatgta gatatagtca cagagaaaat ggaagatatg gcggttgtaa
     3481 aagtgataaa ttatggagaa ccaattccag tgttagattt accaaatata tttgatagat
     3541 tttatagagt tgaaaaatcg agaaatagaa atgttggagg ttctggattg ggtcttgcga
     3601 ttacaaaaaa tattgtaaat ttacatgatg gagaaattac tgtttcaagc gataaatatc
     3661 aaactgtgtt tgaggtacaa ctgccaataa tacaatcagc ttagttataa aataaaagta
     3721 cgattatgtg atataaatat tataacaata aagtgtttac aaaaataaaa aagtgatata
     3781 taatttaagt cagtttaata agatacttat caagaattag gggagagagt tagctcagtg
     3841 atcctatacc aaccttttat caggtggtcc tgctaacaac gatgagatga cttgaaataa
     3901 tatactcttc ttatcaataa tagataggaa gagttttttt tagaattaat gtaacaaact
     3961 ttaaagtata atggaggatt aaataatgga aaaagtagaa agttttaagc tagaccatac
     4021 aaaagtaaaa gctccttttg taagaaagtg tagtgtactt gatggagtaa agggagataa
     4081 agtaactaaa tttgacttga gatttttaca gccaaatgta gaaagttttg gaactgctgc
     4141 tatgcacggt ttagagcatc ttttagctac ttatttaaga gatacattag atggtgtaat
     4201 agacttatct ccaatgggat gtagaacagg attttattta atactatggg gagatgtaga
     4261 tgccaaaaca gttaagattg gtttagaaga agcattaaaa aaagttcttg aatcagataa
     4321 aatgccagca gctacagcca tagaatgtgg aaactacaga gacttatctt tatttggggc
     4381 aaaggaatat gcaaaagatg ttttagataa aggattttct ttaaatatat atggagaata
     4441 atttaattgg aagagaagat ataagcataa atcaaagtga agttttaaga tatttacaat
     4501 acagaggtca agagatagat aaagacctta aatatactat tgatgaatgt gtagctataa
     4561 ctaaaaataa aataaatcct agatatttat ctaggattta tcctattaga ataaataaag
     4621 ataatgttgt agaattagag ggaacaaatt taacattaga gagtaaagat gtatatgaac
     4681 ttttaaaaga atgtaatgag tgtgtaatta tggcagctac tatagggata gatatagaaa
     4741 aagaaataag acgacactct tattcaaatt taacaaaagg actaataatt gattcatgtg
     4801 gaacaacagc aatagaagaa gtgtgtgaca ttgttcaaaa taatttagaa aaggtttttt
     4861 taaaccaaga taaatttata actatgcgat atagcccagg atatggagat ttaccaatag
     4921 aaaaaaatat agatatatta aacgttttga atgctcaaaa acaaataggt ctaacaatta
     4981 cttctaatgg aattatgata ccgagaaagt cagtagtggc tattataggt atttctaata
     5041 caagaataaa taaatctaag aaagaaaagt cgtgtgaaaa ttgtaaaaac tatagaaact
     5101 gtacatatag aaaaggagcg aactcttgtg gaaataagac aatatctgaa aaataatata
     5161 ttaatatttg atggtgcaat gggaacaatg cttcaacaaa aagggttaaa gttaggtgaa
     5221 aatccagaag tatttggtct tcaaaatcca gataaactta tagaaataca tacagcatac
     5281 ttagaggcag gttcgaatgt aattcttaca aatacttttg gatgtaatga actaaaatta
     5341 gatagtaagt atactgtaga agaggtgatt gacaatgctg ttttggtggc tagaaaagct
     5401 atagaaaatg tagataatac taaaccaaga tatgtagctt tagatattgg tcctatagga
     5461 gaaatgctag agcctatggg tactttaagt tttgataatg catatgagat atttaaaaga
     5521 caagtactac aaggcgttaa atctggagtt gatgtaatag taatagagac tatgatggat
     5581 ttatatgaag ctaaagtagc tgtattagca gcaaaagaaa actctgattt acctattttc
     5641 tgtactatga catttgatga aggtggaaga agttttactg gatgtatgcc agaatgtatg
     5701 gtggctacta tagaaggtct aggtgtagat gcaataggag ttaattgttc attaggacct
     5761 aaacaacttt taccaatagt tgaaaaaata gcatcaagag ctacagtccc tgttatggtt
     5821 caagcaaatg caggtcttcc aaatatagtt gatggagagg ctatatatga tgttgatgca
     5881 aaagaatttt ttgaaggggt taaaaagttc gttgaagttg gtgctactat aataggtgga
     5941 tgttgtggta cgaatccaag ttttataaaa gaaatatctg agaatataaa ttctgttaca
     6001 aagggatgta tcgagaaaat tgataaatgt gtagtctgtt caccatcaaa atttgtggaa
     6061 gtacaatcgc ctacagttgt tggagaaaga ttgaatccca caggtagaaa atctctacaa
     6121 gaagcattaa aaaatgaaaa tgttgattat gctataaatt taggcttaga acaagtaaat
     6181 gctggagcac aaatacttgg agtaaatgtt ggtcttccag agattgatga aaaaaaacta
     6241 atgccaaaat taataagaga gattcaagca gtagtagata cacctttaca agttgattct
     6301 tccaatgtag aggccttaga gcaaggactt agatattata atggtagaac aatagtaaac
     6361 tctgtaaatg gcaaagagga gtctttagaa agtatattac caatagttaa aaagtatggt
     6421 tcatgtgtgg ttggacttac acttgatgaa aaggggatac ctaaaaaggc tgaagaaaga
     6481 tttgaaatag caaaaaggat agtcaataga gcagtttctt gtgggataaa accaaaagat
     6541 atatttatag actgtttatc attaactgtt tcagcacaac aagaagaagc aatagaaact
     6601 ataaaagcta taacaatggt aaagacacta ggagtaaaaa ctatattagg tgtttcaaat
     6661 atttcatttg gtcttccaaa taggaaagca cttaatgctt cttttctaac attagcttta
     6721 ggggcagggc ttgatttagc aattataaat ccaaatgaat atagtatgat ggaagctatc
     6781 aattctttta aaatattaaa taacacagat aaaggatgta taaactatat aaatcaatat
     6841 agtaatataa ataattcaaa aaaatcggat tcatctacaa agattgacaa agatttgcca
     6901 ttggatattt tagttgaaag aggattaaaa gatgaagcaa aaaatgtaac actgaatctt
     6961 ttaaaagaga aggatgaaaa ttacatatta gatgagattt taattcctgc tcttgataaa
     7021 gtaggaaaaa gatatgatag cggagatata tttttaccac aattgattca atcagcagaa
     7081 acggtaaaag tttcattaaa tacaataaag gaaactttat taagtaaaag tagcaataat
     7141 gtatccaaag gaaaaataat agttgctaca gtaaaaggtg atatccatga tattgggaaa
     7201 aatatagtaa aaataatgct agaaaattat ggatatgagg ttatagattt aggtaaagat
     7261 gtccctattg aagaagtagt ggaagttgct aaaaagagaa atataaaatt agtaggatta
     7321 agtgcactta tgactacgac tgttcaaagt atgaaagata caattcaggc actgagagat
     7381 aatgagataa atgcaaaggt atttgtagga ggtgcagttt tgacagaaga atacgctgaa
     7441 gaaatgggcg ctgattatta ttcaaaggat gcaaagtctg ctgttgaaat agcaaagtta
     7501 aatttttagc atataaatta aaataaaggt tttactaaat aggatatttt atatataata
     7561 taaatataag ttttagatac ttatgtttaa aacaatagga attaatctat aataatgaga
     7621 ttaattaata taaaaaatat ttatcatcaa cattaaaaag ggctgggaag tctggtataa
     7681 cttccattag ccctttttag ttaaaatcat atgttaaaaa gcccaattac catttttaaa
     7741 aatctgtatt tgttttccat cataagtctc accaataata tccatatcag cagaaccaat
     7801 cataaaatct acatgtgtta aactgtcatt tacaccatgt tcatctaatt cttcatcttt
     7861 taaattgttt ccaccttcca gacaagtctt ataagcagaa ccaattgcaa agtggcaaga
     7921 agcattttca tcatatagag tattataaaa aattatatcc gtattggata ttggtgagtt
     7981 gtatggaaca agagcaactt ctcctaaata atgagagcct tcatccgttt caataagttt
     8041 ttctagtgta tctaatccct tttcagcaga gaaatctatt attttaccat ctttaaatgt
     8101 taagaagaaa ttgtcaatta tgtttccacc ataaacaaga ggttttgtac tataaacagt
     8161 cccatttact ttaaacttat gtggcattcc aaaaatctct tcagttggaa tattcggatt
     8221 aaaacttatt ccattagggt ctttggatgc tccacttagc caaacatgac cctttggcaa
     8281 gtctagagtc aaatcagttt ttgaggattt atattttaaa gttttaaagt tatttttatt
     8341 tagaaagtcc attttagatt taagattttc attatgttct tcccatgctt ttatagggtc
     8401 ctgaccatct actcttgaac atttaaatat agcatcccac agtttttcta ttgctttatc
     8461 ttctgataaa tttggaaaca ctttttttgc ccaatctttt gttggcacag agactatact
     8521 ccatttacat ttatcagtta gagtgtaaga acgccattct tttaaagctt ttccagatgc
     8581 cttctgaaaa tttgcaactc tttcagggtc aacatctttt aataaatctg gattttgggc
     8641 atagactgat aaaaatgccc caccttcttt tgctatatct acatattgtt ctgctgtcca
     8701 tttggggaac tcatgaaatg cttcatctgg agcatacaag tatttaataa gagtactttc
     8761 ttcatcagac cactctatat aaacattttt agcaccacat ttatatgctt ctttaagtgc
     8821 atttcttgca aaatcagcac attctattgg tgactttata agtagaattt gacctggctg
     8881 tatgttaact ccaactttta ttgctaattc agcgtatttt tctaaatttc tatttaaatt
     8941 catatttatc ctcctatatt tttaatattg aataacttat aaagtattat aacattactt
     9001 atgtttttaa tattgaacaa cttataaaat attataactt tacttagatt ttgggtcata
     9061 ttcaaaatat ttatacttta tagattgaga aataaaaaaa atattttaat taaaacagat
     9121 tatgaggata acaaacttat ttaagcagta tgttttttgt tgataataat attaaagtag
     9181 aaataaaaat acttttttag tgaaaagcta tacaagaata ccgaaaaaaa cttataatat
     9241 aataatgaga tagatattta taaatgaaaa aaatttttct ggcaaagctt aattaaaaag
     9301 gtaatagcta gtgttgttat ttaaattagc atagaaaatc aaataaaaaa attatgctaa
     9361 tgtatagaca ttgataaggt agaatttaag ccttttgaat gctatattaa actagagtag
     9421 atattcttat gaatttcaaa atagggcagg aggaaaaagg aaataaaact ataaaaaata
     9481 taaagtattt atataaattt atagagttta tacgtcagaa gatttcagtt aggagggcat
     9541 aaatggagct ttatgaagcc attttttata gaaaatctgt aagaaatttt tccagtaaga
     9601 agataaaaaa gccattgatg gaagaaataa aaagaagttg taaaaattta gaatacttaa
     9661 atgaagattt aaatattaaa gcacatgttg ttgatagagg tcatataata cattttttga
     9721 tgggtaagga atgtaaagta aaggcacctc attatatagt agttacatca gacaaaggtg
     9781 aggactattt acagaatata ggatttgcta cagaaggtgt agttttgcgc cttacaacat
     9841 tgggaatagc tacttgctgg ttggaaggaa acttaaagag agaagatatc ttggaatttg
     9901 tagatattgg gaataagaat tttgaagaag atgaggaaga tgatttagat tatctagctg
     9961 gagtaaaaac agaagaagat gatgaaaaca aaatagaaaa tccttatata ataatagcat
    10021 ttggatatcc agcaaaaaat gaagagttgt ttaggacgag atatgctaga cctgatagaa
    10081 agccagtaaa agatatgata aataagataa ataggaatag aaagtggaaa gatatcttag
    10141 aattgacaag aagagctcca tctgtaaaaa attctcaacc gtggtatttc cataaggatg
    10201 aacgaggtct tcatttattt gaaaagagac ctaagaaaca ctgtgaagat atgaataagg
    10261 ttagcttagg tgtagcctta agacattttg atatagcttg tataaaaaat aaaatagatg
    10321 tttcatatga aaaacttcct ataaggaata aaataggaaa atcatatttt ataactgtag
    10381 tcgagcatgt gaaaccagaa gaagaaaccc aagaagaaaa tgtaactcta gaaaaagaag
    10441 aatcacaaga tgaataaaat tttggaaggg gatattggat atgtataagt gtggaaaatg
    10501 taatcttaga ggctgttcta atggaaatat ggataaatta atgaagatat gtccaactag
    10561 agaaattgaa ctacaacaaa aagcaaagca actttatgaa gaagaagaga atagaaaaat
    10621 agcttataat gctggattag ttgaagcaga ggggtattgt caatatacta gactaaaaga
    10681 gattatagag tttgctaaaa agtgtggtta taaaaagatt ggcatagcat tttgtattgg
    10741 actaaaaaga gaaatgcaaa cagcacaaaa aatatttgaa catcatgggt ttgaagtatt
    10801 ttctgttata tgtaaaaatg gggcaatgcc taagagtaca attggactag aagcatctca
    10861 aacaatatca aagtgttcag atgaggtaat gtgcaatcca ataggacaag ctttattttt
    10921 aaatgaagct aaggttgacc ttaatgtaat tcttggatta tgtgttggtc acgatacttt
    10981 agccatgaaa tatatggaag ctcctataac aactttagtt gtcaaagata gagtaactgg
    11041 gcataatcca gttgctgcaa tatataatgc agaatcatat tttgagaaaa aattgtttga
    11101 taaagatgaa gaataattca aagacttatt gacataaaaa gcaattagtg gtttaattat
    11161 aaaaaagata aaactttaaa ttatcctata gatacataaa gttatataaa taaagaaaaa
    11221 tattacagct aaattcctta aagtagtcca gagagactaa agggttatag ataatgttag
    11281 tatataacct ctagtaaatc ttctagaggt ttttgatgag tataaaataa aaatttaaat
    11341 ataataaagt cttttaaact agtccagaga gactgggaaa gatatctcat agctaatgaa
    11401 tggagttatg tatagataaa atccttatgc ctcttttggt gtgaggattt ttttatgatt
    11461 atttaggctt tattaaaaag gagatgtaaa aatgataaat ggtaaagaaa aattgatagt
    11521 tgcaattgat actgacgaat ttgataaagc taaagaacta atagacagat tagaagatag
    11581 tgtagacata tttaaggtag gtctagagca atacgttgcc acaaaaggta aaacaataga
    11641 ttatcttaaa gaaaaaggga aaaaaatatt tttagacctt aaattccatg atataccaaa
    11701 tactatgaaa agtgcagtga gagctgcagt gagagataat gtttggttaa tgacaataca
    11761 tgtatcagat atggaaggaa tgagacaatg tgcactaatt gctagggaag aagcagaaag
    11821 attaaatata gaaaagccat tagtagttgg agtaacagtt ttaacttcat taagtaacca
    11881 agatttacag gacataggat gtaatatgac aacagaagag ttagctataa agagagctaa
    11941 actggcaaaa gaatcaggca tagatggggt tgtttgttca gcgcaagaag tagataaaat
    12001 agtagaagca tgtggagctg attttataac agtttgccca ggaataagac ctaaatcagc
    12061 agaggttgga gaccaaaaaa gagttgtaac tccatcagat gcaataaaaa aaggtgctca
    12121 ttatttagtt gttggaagac ctataacaaa agcagaaaat ccaagagaat cagctattaa
    12181 tattgtaaga gaaatagaaa atgcttagat aaaatatttg ggaggtagct tatatgaagg
    12241 ggaaattaat tttagaagat ggaacagtat ttgaaggaaa agcatttgga tatctaaagg
    12301 aagctattgg agaagttgta tttaatactt caatggctgg gtatggagaa atattgacag
    12361 acgcaactta ttatggacaa atagttacta tgacttatcc acttatagga aactatggaa
    12421 taaatttaga agatgttgaa tcaaataagg tgcaagtaaa aggacttatt gtaagagaaa
    12481 aaagtgataa cccaaataat tttagatgtg aaatggatat agacacatat ctaaagcaaa
    12541 ataaggtaat aggacttgaa ggaatagata caagagcatt aactaaaatt attagaaaca
    12601 atggaactaa gagaggaatt ataactttag aaaatgtatc attacaagat gttcagtcta
    12661 aattagaaga gcattgtaac aaagattcag taaaaaatgt tacaagaaaa gaaattgaaa
    12721 atataaaagg tactggagct aaagttgtag ttatagactt tggtgttaaa aatagtgtac
    12781 tagagtctct taaagcttgt aactgtgata taactatagc accagcaatg actacagtag
    12841 aagaaatttt aaatataaat cctgacttaa tcttattatc taatggacca ggaaatccag
    12901 aggatataaa tgatatagtt gaaaatataa aaaaattaat aggcaaaaag ccattgacag
    12961 gaataggttt aggacatcaa attttagcat tggcattagg aggaaagact tcaaagcttg
    13021 tatttggaca tagaggaggt aatcacccag ttaaatgttt agaaactgga aaggtattta
    13081 taacttctca aaatcatgga tataatgttt cagaaatgcc agaaaataca gaggtaactc
    13141 acataaattt aaatgacaat actatagaag gaatgagaca taaggaatta ccaatatata
    13201 gtgttcagta cattccagaa tacacaacaa aagaagattt agattgtata tttaataaat
    13261 tcttagcatt aatatagatt tagtattatt tacagatagt aaaaaccatt tagataagga
    13321 gaaaaattta tgcctaaatt agatagtata aagaaaactt tagtattagg gtcaggacca
    13381 ataataatag gtcaagctgc agagtttgac tattcaggaa cacaagcttg ccagtctttg
    13441 aaagaggaag ggattgaagt tgtattaata aatagtaatc cagccactat aatgactgat
    13501 aaagaagtgg cagataaaat atatatagaa ccattaacaa tagaatttat agaaaaaata
    13561 atagaaaaag aaagaccaga cagtttactt gcaggtatgg gtggacaaac agggctaaac
    13621 ctagcagttg aactttatga aaaaggcata ctagataaat atggagtaaa gataataggt
    13681 acttcagtag aatctatcaa aaaaggtgaa gatagagata tatttagaga agtaatgaaa
    13741 gaaataaatc agcctgtaat agttagtgat atagttacag atttacaagc aggtcttgat
    13801 tatgcactta caattggtta tccagtagtt gtaagaccag catacacact aggtggaact
    13861 ggtggtggta tagctgataa tgaggaagaa ttaagagaaa tactttcaca tggtctacaa
    13921 ttaagtcctg ttggacaagt attaattgaa aagagtataa aaggttggaa agaaatagaa
    13981 tatgaggtaa taagagattc aaagggaaat tgtatagttg tatgtaacat ggaaaatata
    14041 gacccagtcg gagttcatac aggagacagt atagttgttg ctccaactca aactttaagt
    14101 aacaaagaat gtgcaatgct taaaaaagca tctttagata tattaaatgc agtagaagtt
    14161 caaggtggtt gtaacgttca atttgcactt aatccacata gttttgaata tgcagttata
    14221 gagataaatc caagagttag tagatcatca gctttagcat caaaagctac aggatatcca
    14281 atagctaaag tttcatcaaa aatagcttta ggttatactt tagatgagat agaaaatgca
    14341 gtaactaaaa aaacttatgc ttgttttgaa ccaactatag attatgtggt ggcaaaaata
    14401 ccaaaatggc cttttgataa atttaaaaaa gcaaatagaa aattaggaac taagatgatg
    14461 gcaactggtg aaattatgag tataggaagt aactttgagg ctgctattct taaagggata
    14521 agatcacttg aaacaggaaa atattcatta gttcacacac catctgagga gagaagcatt
    14581 gaggaattaa agaaaagagt tgtagtacct gatgatgaga gactatttga cttagctgaa
    14641 atgataagaa gaggctataa agtagagatg atagaacaaa ttacaggtat agataaatgg
    14701 tttataaata aatttaaatg gatagtagag caagaagaaa aattaaaagt tatgaaaatt
    14761 gaagatttaa ctaaagacta tcttcttgaa ttaaagaaaa agggattctc tgataaaggt
    14821 atatctgact taatgaagat aagtccagaa aaattatatg aattgagaag tctatacaat
    14881 atcaaaccag catataaaat ggttgatact tgtgcaggtg agatagatgc tatatctcct
    14941 tactattatt caacttatga gcaatatgat gaggtagttg ttagtgataa gaaaaaggtg
    15001 atagtattag gttctggtcc aataagaata ggtcaaggta tagaatttga ctattgttca
    15061 gttcattgtg taaaatcttt aagaaaaatg gacatagaaa ctataatcat aaacaataac
    15121 cctgaaactg taagtacaga ctttgataca tcagataagc tgtattttga accattaaca
    15181 gaagaagaag ttttaagtat aatagaaaaa gaaaagccag aaggtgtaat actacagttt
    15241 ggtgggcaaa cagctataaa attggctaag tttttacatg aaaaaaatat acctatactg
    15301 ggaacagatt ttgatgatat agatgcagca gaagatagag aaaaatttga tgatttacta
    15361 gagagactag atataaatag accaaaagga aagggtgtat ggtcacttaa cgaaggtatt
    15421 gaagttgcta atgaattagg ttatccagta ttagttagac catcttatgt acttggtggt
    15481 caaggtatgg aaataactta taacgaagaa aaattatctc aatatctaca
//
LOCUS       DAMJWO010000091        15459 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.094, whole genome shotgun sequence.
ACCESSION   DAMJWO010000091 DAMJWO010000000
VERSION     DAMJWO010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15459
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.094"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            165..1556
                     /locus_tag="PC366_003105"
     CDS             165..1556
                     /locus_tag="PC366_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF2578599.1"
                     /translation="MSSTESVSKKSGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSIAMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEK"
     gene            1809..3602
                     /locus_tag="PC366_003106"
     CDS             1809..3602
                     /locus_tag="PC366_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2578600.1"
                     /translation="MNIKDRLSGLRKFMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDGIWPDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILDELAKENVQIKPYNDVYEFVKNIDKTEKVLLDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEVELENIRNSHVKDGVAFTKFMYWLKKNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKAKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIVPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(3683..5065)
                     /locus_tag="PC366_003107"
     CDS             complement(3683..5065)
                     /locus_tag="PC366_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF2578601.1"
                     /translation="MSVLKTQEKLKQPRDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLAWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGLSISMYGYRYVFLFSSITVLIGLFFFIFGNRKFYKPLN
                     NNPSNGRESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVIQTGTDPNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISFLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSN"
     gene            5323..5670
                     /locus_tag="PC366_003108"
     CDS             5323..5670
                     /locus_tag="PC366_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF2578602.1"
                     /translation="MIRKKSELQVEVKENLNGGIGKVKLENIIQNEELKGKGRLFKRV
                     ALPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            5688..6722
                     /locus_tag="PC366_003109"
     CDS             5688..6722
                     /locus_tag="PC366_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578603.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKETNSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLKESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARSKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVVWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(6771..7820)
                     /locus_tag="PC366_003110"
     CDS             complement(6771..7820)
                     /locus_tag="PC366_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2578604.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEVGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MVGFAVMSFRENRVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSAGKGGISMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            8095..9630
                     /locus_tag="PC366_003111"
     CDS             8095..9630
                     /locus_tag="PC366_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578605.1"
                     /translation="MIFVKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKNPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNKVSAVGVGKATIYAKCGNKEIERTFRIQARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPVERAISLSSNGNVVGL
                     REGKDRVRITCGDKSKVITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNIDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMRVENISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFNLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNSSQNSDVI
                     NVR"
     gene            complement(9816..10502)
                     /locus_tag="PC366_003112"
     CDS             complement(9816..10502)
                     /locus_tag="PC366_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HDF2578606.1"
                     /translation="MKTIGLIGGMSWESTITYYQVINTVIKERLGGLHSSKCILYSVD
                     FQEIEECQSSGNWEKSAKILADAAIKLQEAGADFIVICTNTMHKVSDKIQESIHIPLL
                     HIADVTATVLREKEIKKVALLGTKYTMEQDFYKNVIINNGIEVLIPNEEDRIIVNDTI
                     FNELCLGIISESSKKAFLSIIDKLGKQGAEGVILGCTEIGLLIKQNDTSIPLFDTTVI
                     HAIEAALSSI"
     gene            10627..12009
                     /locus_tag="PC366_003113"
     CDS             10627..12009
                     /locus_tag="PC366_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2578607.1"
                     /translation="MPINSFENYPMTWKPKLDNRKPPIYKTLAMLLEEDIKRGNLNPG
                     DKLPPQRELADFLDLNLSTITRAFKLCEEKGLICAKVGKGTFISSDVNVSNTLLYQTE
                     SKDIIELGTVHPPYEQNTYIIDFIKNVLKQPEMDRFLQYMSPSGTYMQKKSIAKWIER
                     NNVYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFSGIKSIAKMIGIQLVPI
                     PQENNEISIEYLESYCKNENIKGIYLIPDYHNPTTHTMSDLSRKKIAKIAKQYNIIII
                     EDAINSIFRDGIQTPIFSLASDNTIYIFSTSKFLCAGLRVAFVVAPKRYIENLENALY
                     NMNLMVSPFTAEIVHRLLYSPIIDKIIEEKRDAIIERNEVADKVLSDYNLIGDKNCSF
                     RWLLLPDELDGKSFEISAKNLGVQVYCAERFSVGNSTVPKAVRICVTAPKDVEELEKG
                     LNIIKSLLKS"
     gene            12411..13679
                     /gene="eam"
                     /locus_tag="PC366_003114"
     CDS             12411..13679
                     /gene="eam"
                     /locus_tag="PC366_003114"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HDF2578608.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPY
                     YLSLIDPEDICDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPVYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(13772..14128)
                     /locus_tag="PC366_003115"
     CDS             complement(13772..14128)
                     /locus_tag="PC366_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578609.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(14279..15373)
                     /locus_tag="PC366_003116"
     CDS             complement(14279..15373)
                     /locus_tag="PC366_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDF2578610.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTLMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTIALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
BASE COUNT         5986 a         1912 c         2488 g         5073 t
ORIGIN      
        1 aaataatatt tttcataatt ttaaaaataa taataaaaaa atgaaaatac aggcgataat
       61 ctattgagta aacatagaaa agatgatatt ataagtatgt gctaaaatgg ttaaagcaat
      121 attaatatta aattcaacta taaaacaaaa gggggcgttt ttttatgtca agtacagaaa
      181 gcgtatctaa aaaaagtggt catccgaaga gtttttggct tatttgcatg acaattttgt
      241 gggaaagatt tagttattat ggtttaacag ctttattggt attatttttt acagcaagtg
      301 tagctcaagg tggtttaggt ctttctactc aagaagcaac atccatgttt ggcttattta
      361 caggtcttat atatcttaca ccattagtcg gtggctggtt agcagataaa gttttaggtc
      421 aacaaaaatg tatttctata ggtgcacttt taatagcaat aggagatttc gtactatttg
      481 cttcatctac atctattgcc atggtttggg taggtctatc aataattatt ttaggaaatg
      541 gtttttttaa atcaagttgt tcaaatatag ttggggatat atatcctaaa actgatgtgt
      601 caagaaaaga tgcagcatac agtttattct atatggcagt aaatgtagga gcatttatag
      661 ctccaataat atgtggattg ctttctgata atgtatttgc agtaagagga gcaagtggag
      721 atatagtatc ttatggatat aagatggcat ttttaatttg tggtataggc atgatgttag
      781 gtatgattat atttacactt cttgcaccaa aattattaaa tgaagtcgga aaatatcctg
      841 tgactaaagg taataaaggt gaaaaaattg agtatggacc acttactaag ttggagaaaa
      901 ataggataat agcaatggtt attttatttt tatttgtggt cttattctgg acagcatact
      961 atcaaacaca aagttctttt atgatttatg taagggataa tgtaaataga actctatttg
     1021 gatttgaaat gccagtagca tggcttacat cactaaatgc tatattatgt gtggctttat
     1081 gcccagtatt agctacccta tgggttaaat tatctcatac caaaagaggt gatttctcta
     1141 ttccagttaa aatgggatta ggaatgataa taatgggtgt tgggtttata gttatggtat
     1201 ttgctacatt agctaatggt ccagatggaa tggtaaaggc tagtatattg tttatagtat
     1261 tgacttatat atttacaaca gtaggtgaat tattcttatc tcctatagga cttgcaatgt
     1321 tcaataaatt agctccagct aagtatgcta cattatctat gggagcctgg tatctaacaa
     1381 gtttttttgc aagtttatta tcaggaaaga ttgctggttt tacagccaca cttggttttt
     1441 tacagatatt tggaggaata gcaacagttt taataatatt tggtttaata ttattgggaa
     1501 taagaaatgt attaacaaga ttaatggcta tggatttact aacaaaagaa aaataattca
     1561 tgacgaatta ttgtaaatag atgaattact tcaaataaag gaagttacat ttaaatataa
     1621 aattaaatgt aatttcctct ttgattatga aaaaaagctt tacacaaata gatattataa
     1681 ttaaaattat aattgtgata attagagtgt ataagattta tataaattat acaaaaaata
     1741 tttatgtaat aaactttaca tacttatata tttagttatt caaactatta tttcgaggag
     1801 gtcttgttgt gaatataaaa gatagattaa gtggattaag aaaatttatg gaagaaaaaa
     1861 atatagatgc ctatatgatt ccatcttctg ataatcacca aagtgaatat gtaggagatt
     1921 acttcaaatc aagagaattt atatcagggt ttaatggttc agcagggacg gttattgtga
     1981 ctaaagacga agctgggtta tggaccgatg gaagatattt tatacaggca gaatctcaat
     2041 tagaaggaag tacaataaaa ttattcaaaa tgggacaaga aggttgccca actacagatg
     2101 aatatttata taaaaatatt cctgaaggag gaactttagg atttgatggt agagttatat
     2161 ctgctagaga aggagctaca ttagctgaaa aattatctaa aaaaggtata aagatagaat
     2221 atcagtatga tttaatagat ggtatatggc cagatagacc tgctttatca gatagtaaag
     2281 catttttatt agatgttaaa tattgtggag aaagttttag ctcaaaatta gctagattaa
     2341 gagaaaaaat gagtgaaaaa ggtacttcta ctcatgtaat aactactctt gatgatatag
     2401 catggttatt caatataaga ggtggagatg ttaaatataa tccagttgta ctttcttatg
     2461 cagtaataac tttaaaagaa gtttatttat ttgttgatga aagtaagtta aatgaagaaa
     2521 tattagatga actagctaag gaaaatgttc aaataaagcc atataatgat gtgtatgaat
     2581 ttgtaaaaaa tatagacaaa actgaaaaag ttttattaga tggaactaag cttagttata
     2641 caatttacaa taatatacct tgtgaagttg agaaagttga tgagttcaat ccagtaatgt
     2701 tttttaaagc tcaaaaaaat gaggtagaat tagaaaatat aagaaattca catgtaaaag
     2761 atggtgtggc tttcactaaa tttatgtact ggttaaagaa aaatgtaggt aagatggaaa
     2821 tcactgaaat aagtgctact caaaaattag aggacttaag aagagagcaa gaaggtttct
     2881 ttgagccaag tttcaataca attgctgcat ataaagagca tgctgcaatg atgcactata
     2941 gtgcaactcc agagtcaaat tataaattag aggcagaagg attattttta gtagattcag
     3001 gtggacaata ttatgatgga actactgata taactaggac tacagtttta ggacctataa
     3061 gtgatgaatt aaaactacac tttacttctg tagcaagagg aatgataaat ctttctaagg
     3121 ctaagttctt gcatggttgt agaggatata acttagacat actatctaga agttgcatgt
     3181 ggaatatggg aattgattat caatgtggaa ctggacatgg tataggattt gtgctaaatg
     3241 ttcacgaagc tccaaatgga tttagatgga gagtagtacc tgaaagattt gatagtgcag
     3301 ttcttgaaga aggaatggta actactaatg aaccaggtat atatatagaa ggttctcatg
     3361 gtataagaac agagaatgaa attgtagtta gaaaagctga aaagaatttc tatggtcaat
     3421 ttatggaatt tgaagttgtt acgttagctc ctattgactt agatggtata gtaccagaat
     3481 taatgaataa ggatgaaaaa gattatttaa actggtatca taagttagtt tatgataaaa
     3541 tatcaccttt cttaactgat gaagaaagag aatggttaaa agtttacact agagctatat
     3601 agtttgtact agatacaata aaaatcgagg tattataatg cctcgatttt ttattgtata
     3661 ttttattaac tttaaaaaat ttttaatttg ataattctac taatttttta ttcattataa
     3721 gtagtataat tccaaatatc aataaaaatg atggtatcac tatgaagact tgtaacatac
     3781 caagttggtc tataatagct tgcgtatagc cagataattt atttgctgca aatttgccta
     3841 aaaaccaaac acccattagg aatgaaatat acttttcagg cgaaagttta tttaccatac
     3901 catacccgac tggagaaaag caaatttctc ctatactttg gaatgttaaa aatccaacta
     3961 cccaaaatac acttgctttg tgaattgaat tagggtctgt tcctgtttgt ataactgcta
     4021 ctatcataaa caaaaatgct atagctaata gtataaaacc taagctcatt ttttttggca
     4081 cacttaaatc gcctttttta gtttgagata attttaccca tactaaagca gagataggtc
     4141 caagaataac acaaaggaga ccattgtatg aatctatcca tgaagtagga atttgaaaat
     4201 tgccaacagt aagatttatg tgttcctttg tatagagtgc aatagacata gaggcttggt
     4261 tatatgctat ccaaaaaaat actgtgaaaa aagctaacac caatattact attattcttt
     4321 ttttctcaat caaagttaaa ggtcttgaag cgagcatttt cttatattct agtgattttc
     4381 ttatagactc tctcccgtta ctagggttat tattcaaagg tttataaaac tttctgtttc
     4441 caaatataaa gaagaataaa cctattagaa ccgtaattga tgaaaataaa aatacatatc
     4501 tatatccata catacttata gataatccgc ttttcatagc aaaccattca ttagcaacta
     4561 aaccgcatat taaagggcca aataaagtac ctagattagt agccatatac gtaatagaga
     4621 aagctccatc ttttcttggg tcatcattgg tatataagtt tccaaccata gtatgtaagt
     4681 ttcctttata aaaacctatt cctaatccag ataaaaatat catgatgttt atatccatct
     4741 tactatttgc tatgtatcct agaaaataac caattgaaac cattagcatt ccaagtataa
     4801 tacagttttt gggacctaaa aatctatcac tgacccatcc accaataact ggagagaaat
     4861 aagtccatgc taaaaaagat gcaagcattg atgcggattc tgctggtgtt aaccctaaac
     4921 cacctttgga gacttgttca gctaaaaaca ataataatac caatttcata ccatagtatg
     4981 caagtcctac aaaggtaaat attgaacagc agaaatataa atctctaggt tgtttaagtt
     5041 tttcttgcgt ttttaaaact gacatatgtc gagaacctcc agataaatag tttaacaaaa
     5101 ttttaccata ctatatgagt atatgttttt ttcatataga cgtcaacttg taagataatt
     5161 taattaagtc gaaatatatg taaaaatagt atcatttttg tgtattcagt aatatttttt
     5221 tatgataata tatgttatta ttatattaaa atacaaacat atttatggaa aggatatgcc
     5281 aatttagtag ttagattgat tgtttggcag gtgggatgag ctatgataag aaagaaatct
     5341 gaattacaag tagaagtaaa agaaaattta aatggtggta taggaaaggt taagcttgaa
     5401 aacataatac aaaatgaaga gcttaaagga aaaggaagac tatttaaaag agtagcttta
     5461 ccagtaggaa gttcaattgg tgtgcatgac catacaacag attttgaagt atattatata
     5521 ctaaagggaa aaggtaaagt atttgataat ggggaatttg tagaagtaaa tgagggtgat
     5581 gtagtgtata cagctgatgg cgaaaaacat tctatagaaa atataggaga agaagatctt
     5641 gagtttgtag cactagtttt atatatgtaa aatatggagg aggagtcatg acaggcaaga
     5701 tagaagaaat taaggacaag ataaatagat tttgcaactc caatttaaat caagaataca
     5761 aagatataag ctttaaaatt ttgcaaaacc ttttagataa taataaagag ataattcatt
     5821 cttctagagc tgatatatgg tcttcagcta tactaaatat agttttagaa caaaatcttt
     5881 tatacaataa gaagcatcca ctacatataa caaaaaaaga gttttcaaaa caaataggtg
     5941 tttctttaaa tactataaat aataaatcgt ctttaataaa agatgtttgt agtattgact
     6001 ttttaaatca agatactata gctatttcta atgtagaatt ttgggtaaaa gagaccaatt
     6061 ccaaatcaaa gtctgtagat ttagatttag aaaagaaaaa aatactatat aaaagatata
     6121 ttaagctatc acaagatgcg aatagtgata ttgaatcaat tagatatatg gaggaagctg
     6181 taaatatagg taaaagtatg attactaaag aagataaaga acttggattt tggaaaggtt
     6241 tatctaccag agcctatatg atagcacttg aatcccttgc tagaaagtta gaaagtatta
     6301 ataatctaaa ggagtccaaa aaagtattag aatatttaat agaaattaat cctagtgatg
     6361 agcagggaat aagatacaaa ttattaaatg tattaattag attaaatgat agaacttcaa
     6421 taaataaatt atttgaactt tataaagaag aaaaatctgc tacatggatg tacagtaaag
     6481 ctctttatta ctttaaaaat aaaagtatgt ttttggcaaa tgattctatt aaggttgcta
     6541 gaagtaaaaa taagtacgtt ggattatatt tgttagattg gcgaaatgct tttggtagag
     6601 aatttgttac agaggaagaa aaggcagaag ctgtctatta ctatgatgaa aacatagtgg
     6661 tttggaatga agttaaaggt tctatggatt ggctattaaa aaaaatgttg gaattttcat
     6721 aaaaaaaact actccttact tttatataag taaaaggagt agtttttaat ttatacatct
     6781 agttttaaat cttcaggttt tattagacct ttttttctca taaattctga aatcaacaaa
     6841 gttacaatag caggaagtat aaaattaagt aaaagtatac caacccacat agatatacct
     6901 ccttttccag cactttgcat agcagttact gttccaaatt gtccaaccaa tccacaagta
     6961 cccataccag aaccaatagg aatattctcc attttgaata ttgttgtaga taatggtcca
     7021 agtaatattg aagctacagt aggtggtatc caaattttcc aattttttat tatattaggt
     7081 acttgcaaca tagatgtccc aagaccttgt gccacaaggc caccaactct attttctcta
     7141 aagctcataa cagcaaagcc taccatttgg caacaacaac ctacagttgc tgcaccacca
     7201 gcaagaccac ctaaacttaa catcatacaa atagctgcac tacttatagg taatgtaaga
     7261 gctattccaa caagtgcaga gactaaagct cccattatta taggttgcat agttgtagct
     7321 tgcattatta tatttccaaa tgaagtcata aaagcagaaa cagctggacc aataagttca
     7381 gctacaagta ctccaattag tattgtcaca gcaggtgtaa ccaatatatc tatttttgtt
     7441 tcttttgaaa ctaattttcc aacctctaca gcaaaaagtg tagcgacaaa tgctccaaca
     7501 ggtcctccta attcattacc acaagctcca acaagtgcac aagaaaatag tacaagtgga
     7561 ggtgcttgaa gtccatacgc aatagccact gctatagctg gaccagtaac ctgtttagca
     7621 agagggctta taacttcagt aaaaagagaa atattgaaat tatctcctaa tgtattgaaa
     7681 attgttccaa ttaaaaggga cgaaaaaaga ccaagtgcca tataacttag tgcgtcaata
     7741 agataccttt gaacagaaat ttcaatattt tttcttttag caaatgattt gaaatttctt
     7801 tttttataat tgatttccaa tttaaaatcc tcctcatata atataagtat aatttctttt
     7861 taattaatta tataactttt cagctgacaa gacaaatgtt atttcactaa aattagacta
     7921 ttgtaatagt aagaaattaa cattaatttt agttttaaat tttaaattta tggtttataa
     7981 ttagtatagg gatattctga aatataataa ttttccagtt tatcccaata tttaacttag
     8041 gtagattgct tacaaaacaa atgattatat attaggctaa aaggaagtgg atagatgata
     8101 tttgtaaaaa ataagaaata cagaaaaatt gccataatta tatctattcc tatattgctt
     8161 gttgcgcagt actacctttt taaatttgga atacttagac caatggtaaa gggagtagaa
     8221 attgaaattg tagatgggga atatgttaaa gatatagata aatatgtagt aaaattaaat
     8281 gaaacagtta ctttgtctac aggtgaatat attaaggttc cttcgtatgc taaaaatcca
     8341 aatatttggt ttaatgtatt ggataactca gggactttaa aaatagatgg aaataaaatg
     8401 acagcattaa aggttgggta ttcttctgtg ggtatcatga aaaattcaag agtattaaaa
     8461 aaggctacta taaaagtagt agacccagag gtagaatcac tagatatgga gattaatggg
     8521 gatttaaaac atgttggtga tagtgctact atagaaagta caatagaagt tgattatgat
     8581 aagtttaaaa aatcatataa gccagtttat aagagtagca atgaaaatat tttaaaaatc
     8641 aaaggaaata aagtaagtgc agttggagtt ggtaaagcta caatatatgc taagtgtgga
     8701 aataaagaaa ttgagagaac atttaggatt caagctagag ttgctgaaat aaatatggat
     8761 gatataaaaa tagaagttga ccaaaatgaa aaattgaaac cagatataat aacttctcca
     8821 cctggtttag aaccaccaaa aatatattat gagttagtag attcaaaatt acctgtagaa
     8881 agagcaataa gtttaagtag taatggaaat gttgtaggtc ttagagaagg taaagatagg
     8941 gtgagaataa cttgtggaga taaatctaaa gtaataacag taacagtagt caaagaaact
     9001 ataacgaatg actatataca aaacttggtt ggttcacata aaatagtaaa caataaagtt
     9061 attattaaac ttgaatggga ttatatgaaa gatgtctttg attatgatat atatcttaaa
     9121 gataagttgt caggagaatc atttaagaaa attaaatcta taactataaa tgaaagtgat
     9181 ttaggtaagt ctaacaaggt atatgcaact atagaagtag atatgaaggg taatcaaaat
     9241 atagattttg atatttatgt catagggaaa aaggattcag atacaactaa gccaagtaat
     9301 gtaataaata ttactaatgg aaatggaaat tcaaataatg ataataatat taaagatatg
     9361 agggtagaaa atatatcagc taatgttgat agagataata atgtcattag agttaactgg
     9421 agtagtatat ctcataagga ctgtacttac agtatatatg taaaaaataa tactaatgga
     9481 gatggagaat ttaatctata tcaaagtgat atacagggaa atgagcatac tataagtatt
     9541 cctgaaggag atttaaatct agatatttat gttgttgcaa attataatgg aaatagctct
     9601 caaaatagtg atgttataaa tgtaagatag atttgtatac aaattgaaag tgttgagttt
     9661 atttaaatat taaattaaga aaaaggatag tatagggtaa ttatactatc ctttttttgt
     9721 tacaatatat aggtttaaaa tctctagtaa tataaattat aaaaagtctt atttacacaa
     9781 atctatagat atttttttta ttaatcaata ttgtcttaaa ttgaacttag tgcggcttct
     9841 attgcatgta ttactgtcgt atcaaatagt ggaatagaag tgtcattttg tttaattaaa
     9901 agacctattt ctgtacatcc taatataaca ccctctgcac cttgtttgcc aagcttatct
     9961 ataatagata agaaagcttt ttttgaagat tcagatataa ttcctaagca aagttcgtta
    10021 aatattgtgt catttactat tatacggtct tcttcatttg gaattaagac ttcaattcca
    10081 ttattaataa ttacattttt ataaaaatct tgttccattg tatatttagt acctaataag
    10141 gccacttttt ttatttcttt ttcccttaat actgtagcag ttacatctgc tatgtgaagt
    10201 aatggaatat gtatactttc ttgtatttta tctgatacct tatgcatagt attagtacag
    10261 ataacaataa aatctgcccc tgcctcttgt aatttaattg cagcatcagc taaaattttg
    10321 gcgctttttt cccaatttcc actagattgg cattcttcaa tttcttgaaa atctacactg
    10381 taaagtatac atttagaaga gtgtagtcca cctaatcttt cttttattac tgtattaata
    10441 acttgataat atgtaatggt actttcccaa ctcataccac caattaagcc tatagtcttc
    10501 atattatacc tctcttattt atttattttg aaatagctat ttacaaatac aagtatagca
    10561 tctaaaatag aagcatacaa taataaaatt gtatggagta caattataat taagaggagt
    10621 aattatatgc caataaattc ttttgaaaac tatcctatga catggaaacc aaaattagat
    10681 aaccgaaaac caccaatata taaaacttta gcaatgttat tagaagaaga tattaaaaga
    10741 ggaaatttaa atcctggaga taaactgcct ccacaacggg aattagcaga ttttctagat
    10801 ttaaacttaa gtacaataac acgagcattt aaactttgcg aagaaaaggg actaatatgt
    10861 gcaaaagtgg gaaagggaac attcatttct tctgatgtaa atgtaagtaa tacattatta
    10921 tatcaaacgg aatcaaaaga cataattgaa ttagggacag ttcatcctcc atatgagcaa
    10981 aatacatata ttattgactt tattaaaaat gtactaaaac aaccagaaat ggataggttt
    11041 ttacaataca tgtctccatc tggcacatat atgcaaaaaa agtcaattgc aaaatggata
    11101 gaaagaaata atgtatacac cagtgaagaa aatatattat tatctacagg agggcaaaat
    11161 gctatatgtg caactttact aggattattt aaagctggtg atagaattgc tacagattct
    11221 ttaagttttt ctggaattaa gtcaatagct aaaatgatag gtattcaatt agtcccaatt
    11281 cctcaagaaa ataatgaaat atcgattgaa tatcttgaaa gttattgtaa aaatgaaaat
    11341 ataaaaggca tatatcttat accagattat cataatccaa cgacacatac tatgtctgat
    11401 ttatctcgta aaaagatagc caagatagca aagcaatata atataataat tattgaagat
    11461 gctataaata gcatttttag agacggtata caaactccca tattttcttt agctagtgat
    11521 aatactatat atatttttag tacatctaaa tttttatgtg ctggtcttag agtagcattt
    11581 gtagttgctc caaaacgata tatagaaaat ttagaaaatg cactatataa tatgaatcta
    11641 atggtttctc catttacagc agaaatagta catcgtttat tatattctcc tattatagat
    11701 aaaattatag aagagaaaag agatgcaatt atagaaagaa atgaagttgc tgataaagtt
    11761 ttgtcagatt ataatttgat tggtgataag aattgcagtt ttcgttggtt acttcttcct
    11821 gatgaattgg atggaaaatc atttgaaatt tctgcaaaaa atctaggagt tcaagtatat
    11881 tgtgctgaac gattttcagt aggaaactct acagttccaa aagcagttcg tatttgtgta
    11941 acagctccaa aagatgtaga agaattagaa aaagggctta atataataaa gtcacttctt
    12001 aagagttaaa tttattttac tattatttaa ttaaataaat aaaaaggcgg agaaatttat
    12061 tataataaac ctccgctttt attatttaat gaaatacttt actttttatt aaaaaattta
    12121 attttaataa tcttgaaaat ataatcgttt tatggtaaaa taattcttaa aaatagaaaa
    12181 aattaatcat ttgttaaaaa aaatgcataa tttattgtaa tttattgacg aaggttgaaa
    12241 aatattcata aatgtgcgaa ataacagaaa aaatgcaaaa attaattcaa tttcatttgt
    12301 tataaaatct atatggcaaa attaaatctg cctatcagaa tgatataaac acatcagaaa
    12361 ggaggacgct atcaaataat acaagtagtt aactttgata gcaaaaaatt atgaatgaac
    12421 aaactagaat atccttagag agagctgctg aattaaaatc aaaaattgat gattatattc
    12481 aggctagaaa aacgattaac agaggtcttg aaaaagaaga agagataaat aaacgaaaac
    12541 agaaaatatt aagtatctta aatggaactg aagaggattg gaataactac aaatggcaat
    12601 tatcaaatag aataacagat gtagatactt tatcaaaaat tataactcta actaaaaaag
    12661 aaaaagaata tataaaagag gttggtactc aatttagatg ggcaatatct ccatattatt
    12721 tgagtcttat agacccagaa gatatatgtg acccaataaa attactgtct ataccaacac
    12781 atatagagtt ggaagatgag caagaagatt tggacccaat gggagaagag tatacaaacc
    12841 cagcaggatg tataactaga agatacccag atagattaat aataaatgta acaaatgagt
    12901 gtgctatgta ttgtagacac tgtcagagaa gaagaaatat tggacaacaa gattctcata
    12961 agtcaaaagc tattatccaa gaatctatag actatatcag agaaaatgaa gaaataagag
    13021 atgtactagt aactggtgga gatgctctta cattaaaaga tgattattta gagtggattc
    13081 ttagccaact taaagagata ccacatgttg attatgttag attaggtact aggactcttg
    13141 ttacaatgcc acaaagaatt acagatgaat tttgcaatat gctaaaaaaa tatcaccctg
    13201 tatatataaa tactcatttt aatcatccaa tggaaataac taaggaatct aaagaagctt
    13261 gtgaaaagtt agcaaatgca ggagttccat taggaaatca ggcagtatta ttaaatggaa
    13321 taaataatga taaatttgta atgagatgtt taaatcaaga attactaaaa ataagagtaa
    13381 aaccttatta tatattccaa agtaaacatg taaagggaac aaaacatttc aatacatcag
    13441 tagatgatgg tcttgaaatc atggagtatt taagaggata tacatcagga atggctatac
    13501 caacatatat agtaaatgcg ccaaaaggag gaggaaagac tcctttgctt ccgcaatacc
    13561 ttgtatcaaa aggaacagat tacgttatgc ttagaacatg ggaaggaaaa gttataaaaa
    13621 tggaagatga acctgctgta gatataaaga aacttataaa agagcaagca caggattaaa
    13681 aaagtattta aagtttataa aaagaaacaa ctttaaaata aaaagaaaat ggatgtcaaa
    13741 tttatatcaa tttgcatcca ttttttatta gttatttatt attttgttgt tgattaacta
    13801 attcaagata tccacttggg tggaagtaat atatctcaga agtattttca tttacaaagt
    13861 aaccaatatc accatctgca tctggtaaaa atacataacc attaagattt ttagctttta
    13921 atgcttcaaa atcactagca tttccttgat atatgtaatc aacttcattg ttgtatttta
    13981 ctaaaagttc tttagcttgt tcttgagtca atttagtatt ttggcttaca ggaacattct
    14041 tttgagaatc tgcataagaa gattcattta ctggtgcagt taataacaaa caagataaaa
    14101 ctaataaaga tataagtgct tttttcatac taaaaccctc tttcatgttt aattatataa
    14161 gattcattac ttaataatat tgtatgtttc ctataattaa atattaccat taaagagaat
    14221 aatattacag ttacacagct gtaacttttg attacaaaat cgtaattaaa ttgtattttt
    14281 attccatttg tattttatca tgtctacgat ttacaaactc acagaagtat atctttataa
    14341 cgcccatcac aggagcagat agaatcatac caggtatacc aaagaatcct ccaccaacag
    14401 taactgctag gattgtaaag aatgggctaa gacctagttg tccacctacg atttttggct
    14461 ctataaatgt aacttcaact tgttgaatta ttattaagta aattaaagaa gttaaagcaa
    14521 ttgttggatt ggagaataaa ttaattatta caactggtgc catacctatt actggaccaa
    14581 aatatggaac catattcatg acacccataa gtgtaccaaa taatagtgca tattcagatt
    14641 ttaaaaagta aagaccaatt ccagaaagta ctccaactat aaaagaatct aaaatcttac
    14701 ctgtaaagta tttaccaata tttaaattta agctttgaca tagttctatt ataaagtctc
    14761 catatttttt acctagggaa atataaacta ctttttttgt aaacagtaag aatttttctt
    14821 tttctaataa tatatagaaa caaattataa aacctaaaag aaattgtact ataaattttc
    14881 caactgaaaa tgtagtgcta aatatcccac caagtgaacc aataagcaag ttactaaatt
    14941 taggcattac actcataatt ttgtcaccat actcttttaa tgtattaggg tcaactgatt
    15001 gtaaactctt acctaagtcg aataagaact gctctgtttt atctatgtat gtaggaattt
    15061 gagcaactaa atcagctaaa ctatttacta tggatggaac tgtaaataat ataaaggaaa
    15121 ttagtataac tatgagtaca ccataagtaa gaagtaacga atatattctc ttaaaattta
    15181 atttactttc taagaacttt actagtgggt tgaatatata tgctaataca aatgctatta
    15241 taaatggtgt tagtagtgac attaataaac ttatcactcc aaaaaaatat ttgtaattat
    15301 caataacttt aatcaagata tatgaaacaa ctacagtgag tacaatattt agataaattt
    15361 ttttatcttg caaaataaca caacctttct tatatttatt aaatttagat atacttaaat
    15421 ctaagttaaa gttaatattt atagcttatt atacaataa
//
LOCUS       DAMJWO010000092        15149 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.095, whole genome shotgun sequence.
ACCESSION   DAMJWO010000092 DAMJWO010000000
VERSION     DAMJWO010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15149
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.095"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..391
                     /locus_tag="PC366_003117"
     CDS             <1..391
                     /locus_tag="PC366_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2578611.1"
                     /translation="AKDLKKVYAAITEEVALSELSLLEEKWGNQYAIALRSWRSNWNE
                     LATYFKYPQEIRTLIYTTNSMESYNRLLRKVTKSKSIFPSDDSLHKSLYLATMDISER
                     WTQKIRNWTQILAHLSIYFEERILTLN"
     gene            868..1479
                     /locus_tag="PC366_003118"
     CDS             868..1479
                     /locus_tag="PC366_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578612.1"
                     /translation="MNIKRINLLLSTVMAAVIISLPLAVTANAMEKTESDNNVKIELS
                     DKEVEELHNYWPEDKIFSDEKIDEILIKTGQFTQKELDKINQEVDDSAKKVNQNSRVK
                     YINGYNKYRTFTKNGKNYLYIYVSGKTLKKIKAGTDLASTFGGFLPKIWVELDVVAIG
                     KIITINMDGINTNYGIVLSYIEDKWNFQGATYTYRYDHWFYQT"
     gene            1507..1689
                     /locus_tag="PC366_003119"
     CDS             1507..1689
                     /locus_tag="PC366_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578613.1"
                     /translation="MKKRLYKVFLKTIPNLIIVILSLALSFYTNTFDIDLKILLLIPL
                     AYVLLFIYYYIKTKKD"
     gene            1929..2471
                     /locus_tag="PC366_003120"
     CDS             1929..2471
                     /locus_tag="PC366_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2578614.1"
                     /translation="MLIYLAILELEEDKIKFEKVYEKYRQIMFYVANKILKDDHLSED
                     AVHNAFLRIIKNIDKIDEVDSPRTKAFIVIIVERIAIDFYRKRKREKVSDIEEEYKNR
                     EINFSIEDKVCESNLAIALAKLNESYFQVLSLKFQYGFSNKEIANALNLGEENVYKRI
                     QRARKKLKEILEEMEVGNIE"
     gene            2503..3165
                     /locus_tag="PC366_003121"
     CDS             2503..3165
                     /locus_tag="PC366_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4367 domain-containing protein"
                     /protein_id="HDF2578615.1"
                     /translation="MLRESIPIATKIIIDDLLSDDELNHVFSKGFERKMKKLIKQQKR
                     SSLTNKIIFYSKQTAIVFLIVLASLLTITMSSEALRSRFFRLVIRVYEDLTSFVFSTN
                     GEDNLSLKNKEPEYIPKGFKEVDRVDDFVITYRNDENIEIQYVTDKISSNSIILDTEN
                     AKVKDIFVNGHKAKYIVKGTFLQLFWNDNNFIYLLNVDYQNSGESEFYEDILIKIAKS
                     IK"
     gene            3355..3672
                     /locus_tag="PC366_003122"
     CDS             3355..3672
                     /locus_tag="PC366_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578616.1"
                     /translation="MKSDLYLCKSNKLYRDNEVLEKFMEDLSFLIDDYKFSLETISIL
                     CKINIEKLTNFYAGKGYILYEEMSLIESVLAPFLSAIDIAKHNYDVVIKSRESDKPLI
                     FEN"
     gene            3694..4137
                     /locus_tag="PC366_003123"
     CDS             3694..4137
                     /locus_tag="PC366_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578617.1"
                     /translation="MKRLFALLLTLSLVILPSTLVFANEKAENDSIYAEAPLVFQSNE
                     KAYTHGSGGTAYIGYMSSKHLNWRITSSKGIVILFSGTVEIRNSKNMLVASYPISGGG
                     SSTISGQIDVKYLKKGDYKAILKGTSTTGGGVLVVKSGLVQMFTI"
     gene            4355..4798
                     /locus_tag="PC366_003124"
     CDS             4355..4798
                     /locus_tag="PC366_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578618.1"
                     /translation="MNLRKTVISGMCALVCSSAVAIPAFADEYQDKNIEQYSAVNYID
                     DTMVKMSYIKSGTCNLSISGSTAKVTCFVRGASNVTSTSIIARLQKSNDNGKTWSTIQ
                     TWNASGNISCSLSKSKTIGKGYYRVHSTIKANSESKNIISSTKKY"
     gene            complement(4929..5349)
                     /locus_tag="PC366_003125"
                     /pseudo
     CDS             complement(4929..5349)
                     /locus_tag="PC366_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894307.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
     gene            complement(5327..6604)
                     /locus_tag="PC366_003126"
                     /pseudo
     CDS             complement(5327..6604)
                     /locus_tag="PC366_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899679.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
     gene            complement(6627..7169)
                     /locus_tag="PC366_003127"
     CDS             complement(6627..7169)
                     /locus_tag="PC366_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578619.1"
                     /translation="MLLCDPASAGGSKHDYSAFLVGSESENGLLCGRLAELAKINART
                     DFDKYILHMIYLLKVYPDITHVYIEKNTFNGTAANQLELKIKNDDVLYYRDIEIINEH
                     QKKNKDDKISTLIPVLNKGQMIFAEEDKAFIQQILNFTGQKYSLHDDAPDISAEFINR
                     IFNIKVNESITLLDRRNLGL"
     gene            complement(7209..7427)
                     /locus_tag="PC366_003128"
     CDS             complement(7209..7427)
                     /locus_tag="PC366_003128"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578620.1"
                     /translation="MLFDFKNTNHLEDAKEFYWENEKEIKFPILWPSFWNCLDMALSY
                     YENPTSFKQEVQNDVNSIGEKWFKTIRT"
     gene            complement(7623..8366)
                     /locus_tag="PC366_003129"
     CDS             complement(7623..8366)
                     /locus_tag="PC366_003129"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578621.1"
                     /translation="MDNLERNIQLIFSYMAKTFIRNGATIREAEKEANEIIKTNSSNL
                     WGVNGLAYQLGKINLEFFCMYFIQDTYLPKEDNVAAPIAKVHHELWEDIQESIIGDGS
                     QQLGRIYPRGTGKSAFGDLATTVWSHCYKHKTYTLICSDIGSTAEKFVKDIKNALLEN
                     EYIKKAFGVLLNDNDRKYICNSTQLELTNKTFIEAISSSSPMRGKKYNNNRPDLIILD
                     DYQSEENVRTEDAREKKFKKFSDDVKYAA"
     gene            complement(8666..9223)
                     /locus_tag="PC366_003130"
     CDS             complement(8666..9223)
                     /locus_tag="PC366_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDF2578622.1"
                     /translation="MVVGYMRVSTAEQNEDRQLVTMKKHNVEKMYQEKISAKDTKRSK
                     LNAMLDFVREGDTIIVHDFSRLARSTKDLLEIVELLEKKHVKLISDKENLDTSTPTGK
                     LMLTMLGAIYEFERTNMLERQREGISIAKEQGKYKGRKEVKIDNFGSYYDRYKTRELN
                     KTQLAKELGVSRPTLDRLIKSHESN"
     gene            complement(9418..9606)
                     /locus_tag="PC366_003131"
     CDS             complement(9418..9606)
                     /locus_tag="PC366_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578623.1"
                     /translation="MNNKKKSFLISGTINVILLIIVFALFSYNIIENSTRNMIITVIL
                     IFIFEIIKIKILEKYYNL"
     gene            complement(9617..10192)
                     /locus_tag="PC366_003132"
     CDS             complement(9617..10192)
                     /locus_tag="PC366_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578624.1"
                     /translation="MLKKKIISFLMAGIFVLSSGYNLVYASTFEENEYKQELVNENEF
                     TIINSNENEMIVDKKGNNTYVSTKVTPGSWKNVKYLGQKSRKLSSPYTRERIIQTIQW
                     GLGYLSGGSSFLLGLAESIYREKVYDITKYGGVYTKTYYRRQITDIRNSHANVPVPYR
                     YEYVTYFYSSSNFKKVVYTERVGDGIKLANN"
     gene            complement(10525..11664)
                     /locus_tag="PC366_003133"
     CDS             complement(10525..11664)
                     /locus_tag="PC366_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF2578625.1"
                     /translation="MVIKLTIEEYKNKYSTGDKIILSLKSFDNKELYYHETDNILNSK
                     DEIDRLTSSKIFKIIEDKNDLALESYYSSVIEGAFSTRKIAKSIIRGKMKPSNKSEYM
                     IYNNHRALEYGLDNLDKLYSHKFIYNLHHILGENCLDSEEYEYRTEKVYVCDSKGEII
                     HTGLDPLKIYNFMDELIIFMENSKVNDLVKSTIIHFYFVYVHPFSDGNGRTSRALSYL
                     YLINKGYDTFKEFSISYIISKNRTKYYKAILDVENKGYNLTVFIEFMLKSIIQSINEM
                     RDMHDRKSLESILKEELFENDITLSATEEHILKYICSKDNYSMTLENYIKKNKGRYLK
                     AGIKEIELVDQLMEVFNNLEEIEILSREKDVYKVNEKYLNMLEIS"
     gene            12001..13254
                     /locus_tag="PC366_003134"
     CDS             12001..13254
                     /locus_tag="PC366_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HDF2578626.1"
                     /translation="MLNKKNISSIIMTMILSLSTTVFVFADENTNVKGQDVTKYNEEM
                     VSKNLEDLSIEQLIDIRDKAIDKNLEGLRKFGEDSVKERKDSILNFEFGLVAFVNKNY
                     SNLTEKEKLIRQINIVEYENSINDIMDPSGDFFKVTNQSYQINEFVLKNGKNYKEWSY
                     EYVEFLIEHLEDLCNFVDFDAKYVIEMVDPSIKPDLSDNQKKSLNNELIKMYSSNTLS
                     TNIKDEIENWENNLNINEKNSNEPLPRVSPSSYRQQALAYAKKHGYTNGYYGSTNRKN
                     NAPSPYYNFQKDGYGDCANFVSQCLHEAGVTFWTNNNPWYYYSTSNRSPSWAGAREFK
                     IHWMNRIAYQTLTVSNSLSFLRPATPVSILNSSGVATHTLISTDKHSNGYNFSYAAHS
                     DEGARTNLLKKLEGKKISYYKVYWE"
     gene            13588..14319
                     /locus_tag="PC366_003135"
     CDS             13588..14319
                     /locus_tag="PC366_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578627.1"
                     /translation="MLNKKNVSLIVLVIVLSLFTAIFVFNNRNTNDKSKEIAKNNEEI
                     VPKNLEALSIEQLTKIRDKAIDKNLEGLREFGEDSVKQRKDSILNFEFGLVAFVNKNY
                     SNLTEKEKLIRQINIVNYENSINDIMDPSGSFFELANQSYEINEFMLKNKKNYKEWSY
                     EYIEFLIDHLDELCKFVDFDIKDVIDIIDPTIKTDLSEEQKKSLNDKLKKVSSSDTLS
                     EDIKKEIKNWENNLNSLNMNKNNSN"
     gene            14561..>15149
                     /locus_tag="PC366_003136"
     CDS             14561..>15149
                     /locus_tag="PC366_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HDF2578628.1"
                     /translation="MFNKNEILKKLIEEYDVKTTTDIQDMLKDLFASTIHQMLEAELD
                     DHLGYDRYGNKNKNTKNSRNGYRNKNVKSDFGEITLNIPRDRNGDFEPKVISNYKNDI
                     SGIENQVIGMYSKGMSTRDISSHLKSIYGIDISHSLVAKITDRVLPLAHEWQNRPLDM
                     VYPIVFMDAIHYKVRSEGRIINKAAYIAIGVNLEGI"
BASE COUNT         5629 a         1915 c         1942 g         5663 t
ORIGIN      
        1 tgcaaaagat ttaaagaaag tatatgctgc aattacagag gaagtagcat taagtgagct
       61 atcgctctta gaggaaaaat ggggtaatca atatgcgata gcattaagaa gttggcgaag
      121 taattggaat gagctagcaa catactttaa atatcctcaa gagataagaa cattgatata
      181 tactacaaat tcaatggaaa gttacaatag attattaaga aaagttacta aatcgaagtc
      241 tatttttcct tcagatgatt ctttgcacaa atcattatac ttagcaacta tggatatttc
      301 tgaaagatgg actcaaaaga ttagaaattg gactcaaatc ttagctcatt taagtattta
      361 ttttgaagaa agaattttaa ctctaaatta ataaagaaat atttcaaaaa aattaagaaa
      421 ttttcttaaa gggataataa tttttacaaa aatggaaaaa atatcaaaat aaggctatga
      481 tttttaaagc catagcctta ccaataaatg tttaattatc actaaaaaaa taaattttta
      541 ttcaaagaat acacataaat atttccagac tcacttattg tataagttat attctatttt
      601 gtatgaagtc aattaaaaac tgaactatat taaaattaat tttataaata acaaatataa
      661 ataattacaa aaccttaact gcgttaagtt tgaaatataa taatattaaa aacacttctc
      721 tcaaatcaag tatcttttgt tatattttca taagttttaa aaatataaat tttttaaaac
      781 ttgtgtccaa aaaacaaaat taaatatgtt atatatgtaa agggttaatt ttaaaacctt
      841 aaatttatta tagttagggg gatttaaatg aatatcaaaa gaattaatct ccttttatca
      901 acagtgatgg cagctgtgat aatatcttta ccacttgctg ttacagcaaa tgcaatggaa
      961 aaaacagaat cagataataa tgtgaaaata gagttgtctg acaaagaagt agaggaatta
     1021 cataattact ggcctgagga taaaattttt tcagatgaaa agattgatga gatcttaatt
     1081 aaaacaggtc aatttactca aaaggaattg gataaaatca atcaagaagt ggacgattct
     1141 gctaagaaag taaatcaaaa ttctcgtgtg aaatatataa atgggtataa caaatacaga
     1201 acttttacta aaaatggtaa aaactattta tatatttatg taagtggaaa gacattaaag
     1261 aaaataaaag ctggaacaga tcttgcatct acttttggag gttttttacc aaaaatttgg
     1321 gtagagcttg atgtagtggc aattggaaag ataataacaa ttaacatgga tggtataaat
     1381 actaattatg ggattgtttt atcatatata gaggataagt ggaattttca gggtgcaaca
     1441 tatacttata gatatgatca ttggttctat caaacttaaa agacatgctt ttttaggagg
     1501 aataatatga aaaaaaggct ttataaggtt tttttaaaaa caattccaaa cctgataatt
     1561 gtgatattat cacttgcatt atcattttat actaatacat ttgatattga tttaaaaata
     1621 ttgcttttaa tacctttagc atatgtactt ttgtttatat actattacat caaaacaaaa
     1681 aaagattaat ttttatggaa ttagatatat acgaaaataa ttaatttaaa aatttaactt
     1741 tgagaatcat ttgtagagtt aaggccctta taatcccgaa aatggatttg aagggccttt
     1801 ttactagata tctttaaaaa gcttgttaag catagttata ttctatttaa gtagagttaa
     1861 ttatatattt atgttataat tgaactttaa aatattaatt cagaattttt atattggagg
     1921 aattctaaat gttaatttat ctagctatac ttgaactcga agaagataaa ataaagtttg
     1981 aaaaggtata tgaaaagtat agacaaataa tgttttatgt agccaataaa atattaaagg
     2041 atgatcattt atcagaagat gcagtacata atgctttttt aagaataatt aaaaatatag
     2101 ataaaattga tgaggtagac agtccaagaa cgaaggcttt tatcgttata atagtagaaa
     2161 ggattgctat agacttttac agaaagagaa aaagagaaaa ggtatctgat attgaagaag
     2221 agtataaaaa cagggagata aatttttcta tagaagataa agtatgtgaa agtaatttag
     2281 ctatagcact tgcaaaactt aatgaaagtt actttcaagt gctttcctta aagttccagt
     2341 atggtttttc aaataaagaa atagcaaatg cattaaattt aggggaggaa aatgtatata
     2401 agagaattca gcgtgctaga aaaaaattaa aagaaatatt agaagaaatg gaggttggaa
     2461 atattgagta ataaaaaaga tgattttgat attacggatg atatgcttag agaaagtatc
     2521 ccaatagcga caaaaattat tattgatgac cttctttcag atgatgaatt aaatcatgtt
     2581 ttttcaaaag gttttgagcg aaaaatgaaa aaactcatta agcaacaaaa aagaagtagt
     2641 cttacaaata aaatcatttt ttattcaaaa caaacagcta ttgtattttt aatagtttta
     2701 gctagtttac ttactattac tatgagtagt gaggcattgc gttcacgttt ctttagatta
     2761 gtaataagag tatatgaaga cttaacttca tttgtttttt caactaatgg agaagataat
     2821 cttagtttaa aaaataaaga acctgagtat ataccaaaag gatttaaaga agttgataga
     2881 gttgatgatt ttgttattac atatagaaat gatgaaaata ttgagataca atatgtaaca
     2941 gataaaatta gttcaaattc tattatatta gatacagaaa atgcaaaagt taaagatata
     3001 tttgtaaatg ggcataaagc aaaatatata gtaaaaggaa ctttcttaca gttattttgg
     3061 aatgacaaca actttatata tttattaaat gtagattatc aaaatagtgg agaatctgaa
     3121 ttttatgaag atattttgat aaaaatagcg aaaagtataa aataattttt ttaagtgtcc
     3181 aagggtagcc tcttcattcg ttatacaagt atatatgaaa atgtgaggtg atttttatgg
     3241 ttttaaaatc tacatttacc tgagcgttaa aaatattgtt ataggaaaaa ttaatacatt
     3301 atagttataa catgcttgca ataggaataa aactttaaaa ttgaggtgta aaaaatgaaa
     3361 tcagatttat atttatgtaa aagtaataaa ttgtatagag acaacgaagt tctagaaaaa
     3421 tttatggaag atttaagttt tcttatagac gattataaat tctcgttaga aacaatatct
     3481 attctatgca aaataaatat tgagaaatta actaatttct atgcaggaaa aggatatata
     3541 ctgtatgaag aaatgtctct tattgaaagt gtacttgcac cttttttaag tgcaattgat
     3601 attgctaaac ataattatga tgttgtcatt aaatcgaggg aaagcgataa acctttgata
     3661 ttcgaaaatt aatttaaaac tgggggaata cacatgaaaa gattatttgc gttattactt
     3721 actttaagtt tagttatatt accatcaact ttagtatttg ctaatgaaaa agctgaaaat
     3781 gattcaattt atgctgaggc gccattagtg tttcaaagta atgaaaaagc atatacacat
     3841 ggtagtggag gaactgcata tataggttat atgtcaagta aacatcttaa ttggaggata
     3901 acatcttcaa aaggaatagt tatactattt tcaggaactg ttgagattag aaattcaaaa
     3961 aatatgcttg tagcatcata tccaataagt ggtggaggat cttcaactat atctggacaa
     4021 atagatgtta aatatcttaa aaaaggggat tataaagcta tattgaaagg tacaagtaca
     4081 acaggaggcg gagtcttagt agtaaaatct ggtctagttc agatgtttac aatttaatat
     4141 tataagtaaa ataaaaatca tgaatttatt gggggatagt cacaatacat attatttaca
     4201 gatattcata actattatag ttaaagacat tctattataa agaaaatgta taatttaaaa
     4261 ttataataaa aaaaattatc attagtgtcc aaaaatcact tcttcattcg ttatataagt
     4321 tatataaata gaaaacaaat gaagaggtga ttttatgaat cttagaaaaa cagttataag
     4381 tggtatgtgt gctttagtat gttcatcagc agttgcaata cctgcatttg ctgatgaata
     4441 tcaagataag aatattgaac aatattcagc agtaaactat atagatgata ctatggtgaa
     4501 aatgtcttat attaagtctg gtacttgcaa tttaagtatt tcaggaagta cagctaaagt
     4561 aacatgcttt gttagaggag catcaaatgt tacaagcaca tcaattattg ctagattaca
     4621 gaaaagcaat gataatggga aaacatggtc aacaatccaa acatggaatg cttcaggaaa
     4681 tatttcatgt tctctttcta agtcaaaaac tataggaaaa ggatattaca gagttcattc
     4741 cacaataaaa gctaactctg aaagtaaaaa tataataagt agtacaaaga aatattaaaa
     4801 atagatattg tatttatgag ttgtagtaaa caagaataat agttttttaa aagcaaatat
     4861 aattaatttt aaatagagtg ccaatataaa ataggtgtat aatatttata cttttttata
     4921 ttggcactct attttataaa ataagttatt atagaaaatg aaacataatt tatatataaa
     4981 ttttctgttt gacctggtat ataatctttt atatcacata tcagtatttt cccatcatta
     5041 taaccccaac caatcacagt tgcaggtatc atatcagctt ctccatcata aatgattgta
     5101 tgtttataca tgatttttcc ctcgctatta tctatagttt tattcaaaat accttctgct
     5161 attaatttag caactatgtc tttaatagtc tgtatctgct ttactgtcta caaaacatac
     5221 ttcaattaat atcgctggag cttttgtatg actaagccaa tacaattccc ttacgtccga
     5281 ttttgcacct ctattttcag cagatttata tatatcttca gtcaatttag ttataatctt
     5341 ttgattcatc taataaaatc tctccctctg aaactatttc ctgttctttt ttagcctttt
     5401 ccatttctgc atgaggatta tcaataaaac ttggttgaga taatccggtt tcagtagata
     5461 atttatctcc aagttgactt aatatatttg ctacaactaa atcattatgt ggtatcttag
     5521 gggtaaattt agccttaata tctttataat catagtcaaa accatatttt ttattaagcc
     5581 aaatgcacaa taatttgtac ctattaaata aagtatctgc aatactatca ttattctggc
     5641 tacaaatcca ttctgtactg attaatcttg ctacaactgc taaacttgat gtattacttt
     5701 gcattttttc attgtgattt atatgagatg taattttata tatgttttct tttattgaag
     5761 atagtgtatt ttgaacaaat gtatcattca tgtctttaat aagccattct atttttccat
     5821 ctccattaac ttgaagtatt ccaagttctt tcatccttgg caaatcatct tctttaatat
     5881 tacattcaga gaaggttaaa taagcatttc taaaatcact aatttcatta cttatatcac
     5941 ttaaattagt ttcataagca tcttgtaatc cttttatatc attgaatatt gtattttttc
     6001 ctagttcttc acttctttta caaattgata ttggaacatt accattaaat atattattta
     6061 ctgtaggttt ttctatctct ttaaaatttg aatcaaaatg atatatgtat tctttatcat
     6121 atacatctat ataaatatca tctttaaaat cttttttaaa ttctctaaaa aaatagatgg
     6181 tctctccatc ttcattttca taatggcagc catctgttgg ttttattatt cttactttca
     6241 tttcattgtt ttttacatag taaagttcat agcaaaatcc aaataatagt gtatatctca
     6301 ataaatctga atcgtgcttt ttactccaat ggcaagtata gtattctaaa tcatttataa
     6361 tcttctcatc acctaatcta cttgtatagg tgattttatt tgcaagagaa taagcgacct
     6421 cttcattaat aaactttttt aagaaattag tgtttatctt attattagac ctcttggtaa
     6481 ccattttata gttactaata gcatctgttt cacctttata atacttatac atagtgttgt
     6541 attcttgctt ttttaaactc tagtcttcat atatttctct taataaactt aaatctattt
     6601 ccatttaatg catcacctcc atacaatcaa agacctaaat ttcttctatc taatagtgta
     6661 atactttcat ttactttaat attaaaaatc ctatttataa attctgctga tatatctggt
     6721 gcatcatcat gtagagagta cttttgtcct gtaaaattaa ggatttgctg tataaatgcc
     6781 ttatcctctt ctgcaaaaat catttgacct ttatttaaaa caggtattaa agtagagatt
     6841 ttatcatctt tatttttctt ttggtgctca ttaatgattt ctatatctct gtagtaaaga
     6901 acatcatcat tttttatttt aagttctaat tgattagcag ctgtaccatt aaatgtattt
     6961 ttttctatat aaacatgtgt tatatctgga tacactttta ataaataaat catatgcaat
     7021 atatatttat caaaatcagt tctagcattt attttggcta gttctgccaa tctgccacat
     7081 agtaaaccat tttctgattc acttccaaca agaaaagcac tatagtcatg tttagaacca
     7141 cctgcagatg ctgggtcaca taataacatt gtctttttga atgtatgagt ttctatacat
     7201 tctctagatt aagttctgat tgttttaaac catttctcac ctattgaatt tacatcattt
     7261 tgtacctctt gtttaaaaga tgttgggttt tcgtaataac ttaaagccat gtctaaacaa
     7321 ttccaaaaac ttggccataa tataggaaat ttaatttctt tttcattttc ccagtaaaat
     7381 tctttagcat cttcaagatg atttgtgttt ttgaaatcaa ataacaactc tttgaaatta
     7441 agccataaac cagaattaaa taattcatct acattatcaa ctaaaactcc tttttcacat
     7501 ttaaatttcc aagttggtaa attctttagc ctactataga aacattcttt atgttgtaag
     7561 gttcctaatg ctataaaagt tgttcctctt tttataatct taccatttct tattactggt
     7621 ttttaagcag catattttac atcatcagaa aattttttaa attttttctc tctagcatct
     7681 tctgttctaa cattttcttc tgactgataa tcatcaagta tgataagatc tggacgatta
     7741 ttattgtatt tttttcctct cattggtgat gaagatgata ttgcttcaat aaaggtttta
     7801 ttagttaatt ctaattgagt actattgcaa atatattttc tatcattatc atttaagaga
     7861 actccaaatg cttttttaat atactcattt tcaagtaatg cattttttat atcttttacg
     7921 aatttttctg ctgtagagcc tatatcagag caaattaaag tatatgtctt atgtttataa
     7981 caatgtgacc atacagttgt tgctaaatct ccaaatgcac ttttacctgt tcctcttgga
     8041 taaattcttc ctaattgctg tgaaccatct ccaattatag actcttgtat atcttcccat
     8101 aactcatgat gaactttagc tataggagca gcaacattat cttcttttgg taaatatgtg
     8161 tcttgtataa aatacataca gaaaaattct aaatttattt ttccaagctg ataagctagg
     8221 ccattaactc cccaaagatt gcttgaatta gtttttataa tctcatttgc ttctttttca
     8281 gcttctctta tagttgctcc atttcttata aaggtctttg ccatataact aaatattaat
     8341 tgtatatttc tttctaaatt atccactcgt atttacttcc tcttaattct tctatttttt
     8401 taggttcagt gagtaataca attaataaaa taaacaatgc aaattttttt ctaataaaat
     8461 caccctcttt gaaatatgtc tctggttttt aatttttgct agaaaatttc tagaactcat
     8521 tttctataaa taatactttt ttgaaataga aggatacccc ctatactgaa aaacagttat
     8581 ttataattat tttaaacata attaaagggc ataattctat gaatttgccc cactaaaatt
     8641 aacttaagca tatatattgc tcttcttagt tactctcatg gctctttatt aatctatcta
     8701 atgttggtct acttactccc aattctttag ccaattgagt cttattaagt tctctagttt
     8761 tatatctatc ataataacta ccaaagttgt ctatcttaac ttctttacgt cctttatatt
     8821 taccctgttc tttagctata gagatacctt ctcgttgtct ttctaacatg tttgttctct
     8881 caaattcata tattgcgcca agcattgtaa gcataagttt tcctgtaggt gtacttgtat
     8941 ctaaattttc tttatcacta attaacttta catgtttctt ttctaagagc tcaactattt
     9001 ctaataagtc tttagtactt ctagcaagtc tactaaagtc atgtacaatt attgtatctc
     9061 cttctcttac aaaatctaac attgcgttta gttttgatct tttagtatct ttggcactta
     9121 ttttctcctg atacattttt tctacattat gctttttcat tgtaactaat tgtctatctt
     9181 cattttgttc tgctgttgaa actctcatat aacctactac catctttgat acctccacct
     9241 atgtttactc tataaataat attatagcat aaatgtaaaa ctagagttaa agatttgcca
     9301 tgctttttgt aaattaattg gagttttgat tttattttta catcagaata gatagtttgt
     9361 aatgtaaatt tgtaccagca tactttacaa tatgctctta ggaaagatat ttcttgttta
     9421 tagattataa tatttctcta gtatctttat ttttataatt tcaaaaataa aaattaaaat
     9481 tacagttatt atcatatttc gtgtactatt ttctataata ttataactaa acaatgcaaa
     9541 aacaatgatt aataaaatta cgtttatagt gccagaaatc aagaatgatt ttttcttatt
     9601 attcatatat ttcctcctag ttatttgcta gttttatacc atctcctact ctttcagtat
     9661 atacaacttt tttaaagtta gatgagctat aaaaatatgt aacatattca tatctgtatg
     9721 gaacaggaac attagcatga ctgtttctaa tatcagttat ttgtctccta tagtatgttt
     9781 ttgtatatac gcctccatat ttagtaatgt catatacttt ttctctataa atactctcag
     9841 ctaaacctaa taaaaaagat gaccctccag aaagataacc taatccccat tgaatagttt
     9901 gtataattct ttctcttgta taaggagaac ttaatttgcg tgatttttga cctagatatt
     9961 taacattttt ccaactacca ggtgtaactt ttgttgaaac ataagtgtta ttgccttttt
    10021 tatccacaat catttcattt tcattgctat taataatagt aaattcgttt tcattaacaa
    10081 gttcttgttt atattcattt tcttcaaaag tagatgcata aaccaaatta tatccactag
    10141 ataaaacaaa tattcctgcc attaaaaaac ttattatttt tttctttaac ataatatttt
    10201 actaccttta cttaaatatt tattctataa acactgtcat ataacctgtt agttatatta
    10261 aaaataatct ttttatataa cttcacaatc aaaccttgtc ttatttcata atagttttat
    10321 ttaatatcat ataatttaga cctccttata agattattta tatatataac gaataataaa
    10381 agtaattttg gacaaaataa aaatcttttt attttaagaa tgaaaaattt aaccctctaa
    10441 gaaaactcaa ttaagagcga ttcatagagg gcttattatt atattatata actttatata
    10501 ctttttattt ttatatgctt caatttaact tatttcaagc atattcaagt acttctcatt
    10561 aactttatat acatcctttt ctctagataa aatctctatt tcttcaagat tattaaacac
    10621 ttccatcaac tggtcaacta attcgatttc ttttattcca gcctttaagt atctaccttt
    10681 attctttttg atatagttct ctaatgtcat agaataatta tctttactac agatatattt
    10741 taatatatgt tcttctgttg ctgatagagt tatatcattt tcaaataatt cctcttttaa
    10801 tatactctct aaagacttcc tatcatgcat atcacgcatt tcattgatag attgtattat
    10861 agactttagc atgaactcta taaatacagt taaattatat cctttattct ctacatctag
    10921 tatagcctta taatacttag ttctgttttt agatattata tatgatattg aaaactcttt
    10981 aaaagtatca tatcctttat taattaaata tagatatgat aaggctcttg atgttcttcc
    11041 attaccatca ctaaaaggat gaacatatac aaagtagaaa tgaattattg tactctttac
    11101 taaatcattt actttactat tttccataaa aattattaat tcatccataa aattatatat
    11161 tttcaaagga tcaagtcctg tatgtataat ctcacctttt gaatcacata catatacttt
    11221 ttcagttcta tattcatatt cttctgaatc taaacagttt tcacccaata tatgatgtaa
    11281 attatatata aatttgtgac tatataattt atctaaatta tctaatccat attctaaggc
    11341 tctatgatta ttgtaaatca tatactcact tttattactt ggtttcatct ttcctctaat
    11401 tatagatttt gcaatctttc tagttgaaaa ggcaccttct attacactag aataataaga
    11461 ctctaaggct aaatcatttt tatcttctat tattttaaat atcttgcttg atgttaatct
    11521 atctatttca tcttttgaat ttaatatgtt atcagtttca tgatagtata gttctttatt
    11581 atcaaaactc tttaaggaaa gtataatttt atctccagta gagtatttat ttttgtattc
    11641 ttctattgtc agtttaatca ccaccttagt ttatctttat ctattaatat taacaaaaag
    11701 tattagtttt tacactattt ttgattgttt attttatata ttatgattct actcttgata
    11761 attaaatctt acttaaaaat taattcttga taattaataa aaaaatttat atataagtgt
    11821 ctaaaaaacg attctttatt cgttatatat ataaataata ctagaaaggg aggattatat
    11881 tatgatattt agtaaacgct cttttagaaa aaaacggtga taaacttgtt ttaaatttta
    11941 gtagaatatg atttttgttt tggcaagtat taatacatat attaaagagg gaggtttaat
    12001 atgttaaata aaaaaaatat aagttcaatt attatgacaa tgattttaag cttatcaact
    12061 actgtatttg ttttcgctga tgaaaatact aatgtgaaag gacaagatgt aaccaaatat
    12121 aatgaagaaa tggtctctaa aaacttagaa gatttaagta tagaacaatt aatagatatt
    12181 agagataaag ctattgataa aaatttagaa ggtcttagaa aatttggaga agattcagtg
    12241 aaagaacgta aagattcaat tttaaacttt gaatttggat tagtagcttt tgttaacaaa
    12301 aattatagta acttaacaga aaaagagaaa ttaataagac aaatcaatat tgttgagtat
    12361 gaaaattcta taaatgatat aatggatcct tcaggcgatt ttttcaaagt aacaaaccaa
    12421 agttatcaga ttaatgaatt tgtattaaaa aatggaaaaa actataaaga gtggtcgtat
    12481 gaatatgtag agtttttgat tgagcattta gaggatttat gtaattttgt agattttgat
    12541 gcaaaatatg taatagaaat ggttgatcct tcaataaaac cagatctttc agataatcaa
    12601 aagaaatctc taaataatga attaataaaa atgtattcaa gtaatactct aagtacaaat
    12661 ataaaagatg aaatagaaaa ctgggaaaat aatttaaata ttaatgagaa aaattcaaat
    12721 gaacctttac caagagtaag cccttctagt tatagacaac aagcattagc ttatgctaaa
    12781 aaacatggct atactaatgg ttattatggt agtacaaata gaaaaaataa tgcaccttct
    12841 ccatattata attttcaaaa agatggatat ggagattgtg ctaactttgt ttcacaatgc
    12901 ttacatgaag ctggagtaac attctggacg aataataatc catggtatta ttattctact
    12961 agtaatagat caccttcttg ggctggagca agagaattta aaatacattg gatgaatcga
    13021 attgcatatc aaacacttac tgtatcaaac tctttaagtt ttttaagacc agcaacacct
    13081 gtaagtatat taaatagtag tggagtagca actcatacac taatatctac agataagcat
    13141 tcaaatggat ataatttttc atatgctgca cattcagatg aaggtgcaag aacaaatttg
    13201 ttaaaaaaac ttgaaggaaa gaaaatttct tattacaaag tttattggga ataaataaaa
    13261 atttatactt ttaattaaat gaaaattgaa aagaataaat atctatttca agatccaata
    13321 agtatttagt tgaagcagct attaaatttt attacataat cataaaaaag agactagtgg
    13381 aatttagtct cttttttatg atttaaaaat ttaataaaag aattatataa atttgtctaa
    13441 aaattagttt atcattcgtt ataattatat aaactatatc aaaaaagtgt tctattgtat
    13501 tctttagaat aatcagtaat aaaggttatt ctaataaact gagttatttt ttcacaaata
    13561 aaatacttat taaaaaggag atttgatatg ttaaacaaaa aaaatgtaag tttaattgtt
    13621 ttagtaatag ttttaagttt attcactgct atatttgttt tcaataatag aaatacaaat
    13681 gataaatcaa aagaaattgc taaaaataat gaagaaatag tgcctaaaaa cttagaagct
    13741 ttaagtatag aacaattaac aaaaattaga gataaggcta ttgataaaaa tttagaaggt
    13801 cttagagaat ttggagaaga ttcagtaaaa cagcgtaaag attcaatttt aaattttgaa
    13861 tttggattag ttgcttttgt taacaaaaat tatagtaact taacagaaaa agagaaatta
    13921 ataagacaaa ttaatattgt taactatgaa aactctataa atgacataat ggatccttca
    13981 ggttcattct ttgaattagc aaatcaaagt tatgaaatta atgagttcat gttaaaaaac
    14041 aaaaaaaatt ataaagaatg gtcatatgaa tatatagaat tcttaattga tcatttagat
    14101 gaattatgca aatttgttga ttttgatata aaagatgtaa tagatattat tgatcctaca
    14161 ataaaaacag atctttcaga agaacaaaag aaatctttga atgataaatt aaagaaagtg
    14221 tcttcaagtg atactttaag tgaagacatt aagaaggaga taaaaaattg ggaaaacaat
    14281 ttgaatagtt taaatatgaa taaaaataat tctaattaac tgatagtgta aaatgtacat
    14341 aattataaat aaaataggga tgtcttaaaa ttgattattt tctaatctaa atattttagg
    14401 cctatctaaa aacataagat tatggtctaa aatttgaaat tttagaccat gctttatctt
    14461 tacaataaat gggtctttaa aataaagtgt gtattcttct aaaaagtggt gataattaaa
    14521 atattaaata tcactatata aaggaaggtg cacacttttt atgtttaaca aaaacgaaat
    14581 attaaaaaaa cttattgaag aatatgatgt taaaacaact acagatattc aagatatgct
    14641 aaaagattta tttgcgagta caattcatca aatgttagaa gcggagcttg acgaccattt
    14701 aggttatgat agatatggca ataagaataa aaatactaaa aactctagaa atggatatag
    14761 aaataaaaat gttaaatcag attttggaga aataacttta aatattccaa gagaccgaaa
    14821 tggagatttt gaaccaaagg taattagtaa ttataaaaat gatatatcag gaatagagaa
    14881 ccaagtgatt ggaatgtact caaaaggcat gtctactcga gatatatcaa gccaccttaa
    14941 gagtatttac ggaattgata tatctcattc tctagtagct aaaattactg atagagttct
    15001 acctttagct catgaatggc aaaacagacc tcttgatatg gtttatccaa ttgtatttat
    15061 ggatgctata cattataaag ttagaagtga aggtagaata ataaacaaag ctgcatatat
    15121 agccataggt gttaacttag aaggtataa
//
LOCUS       DAMJWO010000093        14897 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.096, whole genome shotgun sequence.
ACCESSION   DAMJWO010000093 DAMJWO010000000
VERSION     DAMJWO010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14897
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.096"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(72..608)
                     /locus_tag="PC366_003137"
     CDS             complement(72..608)
                     /locus_tag="PC366_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HDF2578629.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRVMLENKDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEVDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDIEEEN"
     gene            complement(626..1939)
                     /locus_tag="PC366_003138"
     CDS             complement(626..1939)
                     /locus_tag="PC366_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HDF2578630.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEENIEDIEPYWVCLPMATRTAV
                     GNYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRAAESLQRYCSIVNKQHGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGVAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVKLPYGHTWKSFTYFLLDTLPENIRNSYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            2275..2715
                     /locus_tag="PC366_003139"
     CDS             2275..2715
                     /locus_tag="PC366_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HDF2578631.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKDGYARLCKLETYLETQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVLIQIGDKQVPAVEKTLVSLTPKA
                     KELWVTRYTCGNNGGWIKYRILEDADLLDIIQYIRAKKSPPKQN"
     gene            complement(2900..3088)
                     /locus_tag="PC366_003140"
     CDS             complement(2900..3088)
                     /locus_tag="PC366_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578632.1"
                     /translation="MNKNNNLVIICMFIGMILGMAIGCAIGISKGNVGITMCYGLIFG
                     MIIGICIGTVIKNSNKKE"
     gene            4149..4544
                     /locus_tag="PC366_003141"
     CDS             4149..4544
                     /locus_tag="PC366_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578633.1"
                     /translation="MNILKMKKTGIFLGGVLFGTVGVKILSSDCVKKTCTRATAGALK
                     VKDSVLETTTKIQENVEDILAEAKEINEQEDLSTSKVNVVQDTLKCEQEVLKTETIKT
                     VEDTNSNNIKCEEIKDNVIEEKNNTCTTE"
     gene            4587..6686
                     /locus_tag="PC366_003142"
     CDS             4587..6686
                     /locus_tag="PC366_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HDF2578634.1"
                     /translation="MNFYIKHEIRGRIRFDLQLGKLNNKQSDTLLYYLTSINGITKAK
                     VYDRTGDAVIYYTGEREYIIREITKFSFNNSKIENLVPEHTSRELNNYYRDKLANKLL
                     VKSISKIFFPKSLRFFLIGLHSIKYFKKGLSSLLNKKIEISVLDATAIGISIFRKDIN
                     TAGSVMFLLGIGELLEEWTRKKSIDDLAQSMSLNIEKVWLKKDATEILVPISEIKEGD
                     LVSVTMGNMIPLDGVIVSGEAMVNQASLTGESLAVNKKEGSYIYAGTGIEQGNIVMCV
                     KEKAGTTRFQKIVTMIEESEKLKSSVESKFEHLADTLVPYSFLGSILTYAITRNPIKS
                     LSILMVDFSCALKLSIPISVLSAMRECNNHSIAVKGGKFLEGVACADTIVFDKTGTLT
                     KAQPTVSDIITFQNYNKKDMLRLAACLEEHFPHSIANAVVYEAEKQGLSHKEMHTEVE
                     YIIAHGISTKVDDKKVVIGSKHFVFEDEKCTIPDGEEDKYNNLSDEYSHLFMAISGKL
                     SAVICINDPLRKEAKYVISNLREYGIKKIVMMTGDSEKTAKSIASKVGVDEYYSEVLP
                     EDKANFVKSEKLKGRKVIMIGDGINDSPAISESDVGIAMSEGAEIAREISDITISADN
                     LNNLIVLKQISNKLMKRVDLSSKFIIGFNLGLILLGVSGFVRPSTSAFLHNASTVGIS
                     LNSMTNLLENTNTYNYY"
     gene            complement(6911..12121)
                     /locus_tag="PC366_003143"
     CDS             complement(6911..12121)
                     /locus_tag="PC366_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HDF2578635.1"
                     /translation="MANKLYSEIVNLLEEGRDELRKYDLKEKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDEETGQIYITAKDSAVEIGNGVYSKTLCPEVVDIANRNFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRHTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKTLIGNVTEEKIRNILEKAKEDLDSQEKDYDGCKELVYL
                     LNVALSDGVSIKLCNPLDRQPEKLLDEMKNLPETFEKTDLGLMLTASCKIEIQKAVDV
                     TYKDLEKLLVPYIESVKKGMEDSISILSSINSLKDKKTQLDKMYTDLCSRTNNMKELM
                     EFVQELSYGDGVQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYREEEAKKLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLTK
                     IISGYQLNILSSIYMYGDCELKIDCNMEKEVFSGKNIVLLTEKLCIPEGIYSINVSGK
                     DAEKLVGEGSIYDGMNGRNGNNAGTSGDILLSFKEIEKRGELKLYVDGGRGGNGQDGK
                     RGDTGITGEAGENAKIGSKKESKEFAKVKGTKYYVVKAEKGKQGGTGGTGGNGGNAGL
                     GSKSGQVYLLGKASLLKGAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GTSAPIDDSDRNYYYFDRYVFNHASNENQVADDGEKLNALYEKHKDWTISKREDSGLV
                     GAEGKDGRSGDALKEKELLKQEYSLSIDTFFYEFFERFGFSGIKGYRNLRLLCAVGIL
                     EADILELSHIYEIFHAVEKIEMQLNREILQKYYSFEKKNKAVLSLDDMNIKKEFYKEA
                     KEIYEYLINKLMQSDRIESFIGEKKNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKTLRELEQGKKDELKEGYFNTYKESILTQIESGNQQIEVLKDELENK
                     MLSVNAKMNLLIQEIIKMKEEEQEDIEELKKKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYQWTNRMVDFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEERRTKFDQIKEIIVKSIDDDNYAEKADDIQRAKEGLSESE
                     YKEIYTKIQKKEIGMLEANYNNKQQKDKLAALEKSKQAIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLNVKSSFESKIEVVKEAIKDKENNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELSTKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSGSGNQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVINQAKEQNRQIREFLDQDAYQWQ
                     KTDNHILKVALTGSLDGKSRVGFENTYSLYDCNEEEVKKLLTGDEISFEVPLNKNFDA
                     IKYVTMYANIPNLRRNILEDSLKVKVHIHLYDSGYFSLYDDKKDVYYQYVFPQNYIDI
                     THGLDVKYNDSDSINSIWSSVEDKGIEKFKNAGLNSGRSPYSMAKISLKAHFNKKLSY
                     DSLTNEQKKKLESYFDKPSKYAWSESIDILKSLGYIDLKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVDLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIIC"
     gene            complement(12136..14259)
                     /locus_tag="PC366_003144"
     CDS             complement(12136..14259)
                     /locus_tag="PC366_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2578636.1"
                     /translation="MQNSVKQEPCDFSHGRFRPEADILDSRLTKVLDLFQQLNMCLHK
                     DNFRGSITFFISKSFLGRTEKQIYNVIKRKYEQLCENLDSNIEEKAWLFEELLKDNGK
                     NIHLCKPLESDEREGLLKQVLELDEVKDKTSAFQYPISADARLVLDTLIKEIQNNIVS
                     SLEDYVKAYTEDFISIIGSITMIQEIAKYDEVVKVFKNWLESTTTLTIERFINVLAKQ
                     SGLFLQDSCMELQNKIKGNLDIIDALSKYTEHGTGEILLPSVHMEFIIEKASKKIMEQ
                     NFIIIRKNLEKVLVSYEVQKQVFTLPNREKLMEVANKKDYVYSVSDFNSILTNVTVTQ
                     NEELEDSITRLSAYGEEGNEIIREFIGKYILNPFIVKTININDKKGIEIRALIPNLVI
                     SSVLEYFKNRKVDDNVSTFMFFAKDTIYMDDNLGMDFASEKNIILACNNLDVGSNVKI
                     NVSGKSGELVDSSMYGKNGEDGRDAGNIYLYIKEEIRNYRLTLIANGGNGSKGIDGKN
                     GETGDSGSNGADAGYTSSFHGQMFKGYFAKGTSGKKGDKGGAGGNAGRGGNAGNKGNI
                     YFISDSEEQKNRIINHCDITVKDGEAGPNGRPGSGGYGGSGGYHGYNTLSFSPSGIDK
                     TVYYTGYFTSWDYKLDSIIKYHIEFSGGSWNEGKTGPAREYAEYGDRGDDGGFNAPNT
                     KLSTAVSKVEENLIKEKYQGYCSEI"
     gene            complement(14324..>14897)
                     /locus_tag="PC366_003145"
     CDS             complement(14324..>14897)
                     /locus_tag="PC366_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2578637.1"
                     /translation="GLDLGIKEFCISSCGDFIENPKYLKKSLNKLAKLQRELSRKTIG
                     SLNRNKARLKVARLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNMIKNRKLSR
                     LISDVSWSEFIRQLKYKANWHGRQIVKVGKFFASSQICNKCGYKNEEVKDLSIREWIC
                     PSCNETHDRDINASINILKEGLRLITIQNK"
BASE COUNT         4882 a         2712 c         1664 g         5639 t
ORIGIN      
        1 aagctcttta ttttcaatat atattttaaa ttttctcttt ttaatatatc tttttctttt
       61 aataaatctc tttaattttc ttcttctata tcagagccaa agggaatcca tgcattacca
      121 aactctttat ctttaaataa ataagctaat ccagttattt gcttcaatct aagaatttca
      181 tcaacttcca tacccaggtg ctttgatatc cattcatcag attttccaat ttcacaaagt
      241 tcagttataa ttttactcat taaatccaca ttatgagaac ctcttgcacg attgtgtcga
      301 atagtacttg ccattctttc atcaagagat ttatcaatta ctgaaacagg aagaagtccg
      361 ttttctctat catatatatc cttattttca agcattactc tatatctatg aaaaccatct
      421 acaataatat acttatcctt ttcctcatta taataacaga caattggcat tgtataccca
      481 tcttctttta tacttttata caacaactgc atttctggtg gggctactgc atttggatta
      541 tagtcgttag attctatctt ttcgattggc actgcgatga ttccatatac aggactttta
      601 tattccatag catcttaact cctatctaat gaattttttc atatttcttc ttaatatatt
      661 ccgttctaat tctctgttct tttgtaggac caaatcccat aaatctacac atatggtcat
      721 tttttaaaat acaataacac attcttttcc aacttggtat atctttggta aatttaatat
      781 catccgtatc atcaggtata tcatccaaaa atatgactct actcttttta tcttttgtat
      841 gatttgaaac tccatttaat tctattttat aaccttttct caacaattca cgtataacta
      901 tttctgacaa accaccacct gtattctgcc aaaactcaat agatgttgaa aattttttaa
      961 tatagctatt ccttatattt tcaggtaagg tatcaagcaa aaaatatgtg aaacttttcc
     1021 atgtgtgtcc atatggcaat ttaacactac gatatcccat agcttttgtt tttccataaa
     1081 tagaagtaaa attaactcct tgtactctag caaccaattt cacccataca tctgggtcca
     1141 atattctgta taaatttaaa ctctcttttg ctgaatcatt aaaaggtgat gccactctca
     1201 tttttcttgg agctactcca gctttataga ataagtcata aattttatta tagtcataat
     1261 caaatttata gtgggctaac catatatctt ctatttccca atcatatata ggagatgccg
     1321 tccagacatt tttaaattcc ttagttatcc agcactttcc tttatatcca tgctgtttat
     1381 tcacaataga acaataacgt tgtagagatt ctgctgctcg tgttcctaat aagcaaacaa
     1441 cttttgcacc ttcatgtata tctctaatcc atctaccaaa ttgctttgcc aaactttctt
     1501 gtctcatttt atacttataa taagtaaaag gattattttt ttgatttatt atgtattctt
     1561 tgactggcat ttctcttacc cataattctt ctttctcatc atcccatgga taccaataca
     1621 tttcataatt tcctacagca gttcttgtag ccattggtaa acacacccaa tatggttcaa
     1681 tatcttcaat attctcttca aatacttttt caacatattc agtagtcaaa ctatattgag
     1741 cctcaaaatc ttgatgaaat actcctattt tggaacttat attattcttt ctcttataat
     1801 ccaaaactaa atttagcagt aagccactat cttttcctcc actaaaagat acatagatat
     1861 aatcaaattc attaaaaaga taagaaagtc tttcttgaaa agcttcaaat acatcggatt
     1921 ctaaatatct cttatccatt tgaattatcc cctttcaatt agaagtttat aaaaccttac
     1981 aatacaatat tattatgctt ttttagcagt aatcagcata aattatacat tatttaaata
     2041 cacaaatcca actaaacaca tataattata atgtaattat acttttgtat tataaactat
     2101 attttatcat tattttacat ttttttccaa tatatataaa tatcatattt ttctattagc
     2161 taaaaataat tactttatat ttttacatgt tagtataata agacataaaa acttgacata
     2221 ctgttgtcat aattactttg ctataattaa aagtaaaaat ggaggtaaat tataatgtat
     2281 gaacgtatgc ttgataaaag caataaaccc tgtttgtctc aaataataga atatataggt
     2341 aaagatggat atgcacgatt gtgtaagttg gaaacttact tggaaactca atataattta
     2401 tcaagagaac ttcgatttcc ttttggaaac aattatggtt ggggttacaa atatagccat
     2461 aaatcttttc atttatttta tgcttttttt gaaaaaggtg catttactgt tctgattcag
     2521 ataggtgaca agcaagttcc agcagtagaa aaaacgttgg tatctttgac accaaaagct
     2581 aaagaactct gggtcactcg ttatacttgt ggcaataatg gaggttggat taagtatcgt
     2641 attttagaag atgcagactt acttgatatt attcaatata taagagcaaa aaaatctcca
     2701 cctaaacaaa attaactttt attttttgtg atttaaatat agtgtatata aattccattc
     2761 tttccatatt aaaaaaataa tataaaaaat atctattagt atatcttatt tagtatgtct
     2821 tattctactt tttacagata attaaaaagt tttatcataa ataaatcata actaaacatc
     2881 ctagtaaatc aaaattcatt tattcttttt tattagaatt tttgataaca gtccctatac
     2941 atatgccaat tatcattcca aaaattagac cataacacat tgtgataccc acatttcctt
     3001 tagaaatacc tatagcacaa cctatagcca ttccaagtat catgcctata aacatacata
     3061 taataactaa attgttgttt ttattcatag tttttctcca ttcaatatat tttaaattgc
     3121 ctagctcgcc ttcttagctt aaaacaaaga aatataaatt aactttcttt cattctaata
     3181 tctgcttgta taaatgtcaa acaacacatt tcttgtcata acctcctctt tttgaagtaa
     3241 gtacaatctc ccagacacaa taatatcaat ttcctaaaac catttaagta acttttatat
     3301 ttacataata tttacaatca taaactatat tgttattcat ttatacatca taaacactcc
     3361 ctcctaatca ttattatact taaaataatg ttcatttata ataatatatc taacgcactt
     3421 taattgaaaa aactaaaact ttgcctttca ttcccatata taaataagta tactttttga
     3481 tgctctatta caaatcaact aaattaattg atataaatta tcattttctg ttgaaaatac
     3541 catttacaca tgctatactt aattgcataa atggtaataa atgtcatatg attttacaaa
     3601 tctattaata acaattatta cttttactgt attttaaagt ttttggacta aatatcaaga
     3661 actttctaaa atacaaagta caaaaaattt atataagtta taaatttata tgaactagat
     3721 aagctcaaac aatatgttat gtataaactg tgtagtattc ggttataaat ttatataaat
     3781 tatataagct atataaagta ttacctcaac tatataagct agatatataa attacataca
     3841 taagctagat atataaattg catatataag ctatataaga attatttcaa ctatataaac
     3901 tacatatata aattacatac ataagctaga tatataaact agatatataa actgcatata
     3961 taagctatat aaaaattatt tcaactatat aaactacaca tgtaaaattc atgtaaattt
     4021 actaatataa atcaaataaa attactaaac tctctaaact aattttgtaa aacatactct
     4081 atttttaaca tttgttacct tatacataag tataaacaaa atctaactaa atgaaaggat
     4141 aatgtaaaat gaatatttta aaaatgaaaa aaacaggaat atttttagga ggagtacttt
     4201 ttggtactgt aggtgttaag atactttcaa gtgactgtgt aaaaaaaact tgcactcgtg
     4261 caacagcagg agcattgaaa gttaaagatt ctgttcttga aacaactacg aaaattcaag
     4321 aaaatgtaga agatatttta gctgaagcaa aagaaatcaa cgagcaagaa gacttatcta
     4381 catctaaggt aaacgttgta caagatactc ttaaatgcga acaagaagtt cttaaaactg
     4441 aaactataaa aactgtagaa gatactaatt ctaataacat taaatgtgaa gaaatcaaag
     4501 ataacgtaat tgaagaaaaa aataatactt gtacaacaga ataaatttaa tgattattat
     4561 gattaataat atcaggagga agtaaattga atttttatat aaaacacgaa ataagaggtc
     4621 gtatacgctt tgacttacaa cttggcaaat taaacaacaa gcagtccgat actctcttat
     4681 attatttaac ttctataaat ggtattacca aagcaaaagt ttacgataga actggtgatg
     4741 cagtcattta ttacactggt gaaagagaat acataataag agaaatcact aaattcagtt
     4801 ttaacaatag caaaatagaa aacctagttc ctgaacatac cagcagggaa ttaaacaatt
     4861 attatagaga caaattagca aataaactgc tagtcaaaag tatctccaaa atattttttc
     4921 caaagtcctt aagatttttt ttaattggac ttcattctat aaaatatttt aaaaaaggtc
     4981 tctcttccct actaaataaa aaaatagaaa tttctgtttt agatgccact gctataggta
     5041 tttctatttt tagaaaagat atcaatacgg ctggttcagt tatgtttctt cttggtatcg
     5101 gtgagttatt agaagaatgg actagaaaaa aatctataga cgacttggct caaagtatgt
     5161 cactaaacat tgaaaaagta tggttaaaaa aagatgccac tgaaatacta gttccaattt
     5221 cagagataaa ggaaggagat ttagtcagtg taactatggg aaatatgatt ccattggatg
     5281 gagttatagt atcaggagaa gcaatggtca atcaggcatc acttacaggt gaatcccttg
     5341 cagttaacaa aaaagaaggc tcttacatat atgctggaac tggaatagag caaggcaata
     5401 ttgttatgtg cgtcaaggaa aaagctggta ctactagatt ccagaaaata gtaactatga
     5461 ttgaagaatc tgaaaaacta aaatcttctg tagagagtaa atttgaacat ctagcagata
     5521 cattagttcc atacagcttt ttaggaagta tattaaccta tgcaattact agaaacccta
     5581 taaaatcact ctctatattg atggtagatt tctcttgtgc attaaaactc tctatcccta
     5641 tttcagtact atcagccatg agagaatgta acaatcacag cattgctgta aaaggtggaa
     5701 aattccttga aggtgttgca tgtgcagata ctattgtatt tgataagaca ggcacattaa
     5761 caaaagctca accaactgtt tcagatataa ttacattcca aaattataat aagaaggata
     5821 tgttaagact tgcagcttgc ttagaagaac acttcccaca ctccatagca aatgcagtag
     5881 tttatgaagc tgaaaaacaa gggcttagtc acaaagaaat gcatacagag gtagaatata
     5941 ttattgctca tggcatttca acaaaggtcg atgataaaaa ggttgtaata ggtagcaaac
     6001 attttgtatt tgaagatgag aagtgtacta tcccagacgg tgaggaggat aagtacaaca
     6061 atctatcaga tgagtattct cacctattta tggcaatatc gggtaaatta tcagcagtta
     6121 tttgcataaa tgacccttta cgaaaagaag caaaatatgt aatttcaaat ttaagagaat
     6181 atggaataaa aaagattgtg atgatgactg gagatagcga aaaaacagct aaatctatag
     6241 caagtaaagt tggtgttgat gaatattatt cagaagtctt accagaagac aaagccaatt
     6301 ttgttaaaag tgaaaaacta aaaggtcgca aagtaattat gattggtgat ggaatcaatg
     6361 attctcctgc tatttcagaa tcagatgtcg gaattgcaat gagtgaaggt gctgaaatag
     6421 caagagagat ttcagatatt accatatcag cagataattt gaataattta atcgttttaa
     6481 agcagattag taataagctt atgaaaagag ttgatttaag ttctaagttt attatcggct
     6541 ttaatttagg tctgatttta cttggcgtaa gtggatttgt tagaccaagt acatctgcct
     6601 ttttacacaa cgcatctact gttggaataa gtttaaacag tatgacaaat ttattggaaa
     6661 acaccaatac ttataactac tattaatccc cattatataa aacatatgta tataaaaaat
     6721 ttataattca tcttttaaaa agaaactgtc ttaaaaggag cttttttcta atcaaaatta
     6781 tataaaacat attttacaaa ttttaaactc aacttatttc tattttttac aaaaaggaga
     6841 tgattcaaat tttcattttg aaacatcccc ttttgtaaat ttctttaaaa cttatatatt
     6901 aattatattt tcaacaaata attgtatttt caaccaatct ttcttcatag cattttaaat
     6961 cattttgctt tagataatta aattcagact ctacataaat accacagcct accaattcaa
     7021 ttgtcaaatt aggtatattt tcctttagta tactagtctg ctcataaata attctttcca
     7081 ataaatcaac ttgtaatata gaaaaatgct tcataatctc cccatcacta tctatatctt
     7141 tcttgatttc ataccaactc tttgacaaaa ttcccttcaa atcaatatac cctagactct
     7201 tcaatatatc tatactctcg ctccatgcat acttactagg tttatcaaag tatgattcta
     7261 gtttcttctt ctgctcattt gtaagtgaat cataagaaag cttcttatta aaatgtgcct
     7321 tcaaagaaat cttagccata gaatatggac ttctaccaga gtttaatcct gcatttttga
     7381 acttttcaat tcctttatct tctactgaag accatattga gtttattgaa tctgaatcat
     7441 tgtatttaac atcaagacca tgtgtaatat ctatatagtt ttgtggaaat acatattgat
     7501 aatagacatc ttttttatca tcatataggg agaagtatcc actatcatat aaatgaatat
     7561 gcacctttac ttttaaacta tcctctaaaa tatttcgtct aaggttcggg atatttgcat
     7621 acatggttac atattttatg gcatcaaagt ttttatttaa tggaacttca aaactaattt
     7681 catctcctgt caaaagcttt ttcacttctt cttcattaca atcatataga gaatatgtat
     7741 tttcaaatcc cacacgtgat ttcccatcta aactgcctgt taatgctacc ttcaaaatat
     7801 ggttatccgt tttttgccat tggtaagcat cttggtcaag aaactctcta atctgtctat
     7861 tttgctcttt cgcctgattt ataacctcgt tttcatcttc tgtaatacct acatggcatc
     7921 tatttaagat atttactata ttgcttccaa atggaaacgt ccatagttga aaagctgctg
     7981 cctcaacctg acacaaatat ctaacctgat ttaattcaat ttgatggata agttttttct
     8041 gatattcatt catctgatta ccactacctg acatttgata aatcaattct cccattgcaa
     8101 gattatcttt tttcttatca atcttatcag taatgataat ttgagtttcc atcatatcct
     8161 gtactttttt aaatattata gaaatctcct ctgaattttc catttttaag cttccaaact
     8221 ttgtgcttaa ttcagttaaa acttccttca tctttaattt acttatctca ttttcaaaaa
     8281 tatcttgatt tttaactgta ctatcgaatt tttctacaaa tggtataaca gattctttca
     8341 aagttttatc tttaaattcc accatttgag tattcaattc atctaatttc ttaatattat
     8401 tttctttatc tttaattgcc tctttaacta cctctatttt actctcaaaa ctagatttta
     8461 cattaagaca attattaaca ccactaatcg cagtatttat aagagaacaa gcagaacttc
     8521 caatactcaa tgcattttta attttagatg tcttttgctg tctttcaata gcttgtttac
     8581 ttttctctag tgcagctaac ttatcttttt gctgtttatt attgtaattt gcctccaaca
     8641 tacctatttc ttttttctgg atttttgtgt aaatttcctt atactcgctt tcacttaacc
     8701 cctcttttgc tctttgaata tcgtcagctt tttctgcata gttatcatca tctatagact
     8761 taactataat ctccttaatt tggtcaaatt tagttcttct ttcttcatca acacctgcca
     8821 aattataagt cattttatct aaagcatttt ttctatcttc acttagctgt tctccaagta
     8881 caaatctcat accatcagaa tccaatttaa aatctgaaaa atcaaccatc ctgttagtcc
     8941 attggtattc ctcttcttta gctgaaagat tttccttcaa agattttgca ctgtcaaatg
     9001 cccctagaca agcttgacca acaccactaa atgcagtcag taaactcaat gcgctttgta
     9061 ttccagaaag aattaactgt gttttcattt gttcctcaag ttttgcctgt ttctttttta
     9121 gttcctctat gtcttcttgc tcctcttctt tcatctttat aatttcttga atcaacaggt
     9181 tcatctttgc attaacagaa agcattttat tctcaagttc atcttttaaa acttctattt
     9241 gttgatttcc agattcaatt tgagttagga tactttcctt ataagtattg aaatatcctt
     9301 cttttaactc atctttcttt ccttgttcca attctcttaa ggtcttgtcc agataatctg
     9361 tcaaagaacg aatatctgta acacgatttc ctccaatttc actttcttca atcatctgca
     9421 catagaatgc tgttttttgt tcaagtgcaa ataaaatcat actccattcg ctaaaattct
     9481 tcttttctcc tataaaagat tctattctat cagactgcat caatttattt ataaggtatt
     9541 catagatttc ctttgcctcc ttataaaatt ctttctttat attcatatca tccagagaaa
     9601 gcactgcttt atttttcttc tcaaaactat agtacttctg aagtatttct ctatttaatt
     9661 gcatctctat tttctcaact gcatgaaaaa tttcataaat atgtgaaagt tctaaaatat
     9721 cagcttctaa aattcccact gcacacaaca gtctaagatt tctataacct ttaattccag
     9781 aaaaaccaaa tctctcgaaa aattcataga agaaggtatc tattgacaaa gaatactcct
     9841 gctttaacaa ttccttttct tttaatgcat ctccagagcg accgtctttt ccctctgctc
     9901 cgactaaacc tgaatcttca cgtttgctaa ttgtccagtc cttatgtttt tcataaagag
     9961 catttaattt ctctccatca tctgctactt ggttctcatt tgaagcatga ttaaacacat
    10021 atctatcaaa ataatagtaa tttctatcac tgtcatctat tggagcagag gtacctatat
    10081 atcttattgt ttcttcatat atacctctaa ttccaccaag acctcctgca ccaccagctc
    10141 ctccagagcc tccttttcct gctagaccat gatttccatc ttttttactt atagcacctt
    10201 ttaataaaga agcttttcca aggagataaa cctgtccaga cttgctccca agacctgcat
    10261 ttccaccatt acctcctgtg cctccagttc caccttgttt tcctttttct gcttttacca
    10321 catagtattt tgtaccttta accttagcaa attcttttga ctctttttta gaacctattt
    10381 tagcattttc cccagcttct ccagttatcc ctgtatctcc tctttttcca tcttgtccat
    10441 ttccaccacg tccaccatct acgtaaagtt taagttctcc tcttttttct atttctttaa
    10501 aagataataa aatatcacct gaagtacctg cattattgcc atttcttcca ttcattccgt
    10561 cgtaaataga accttctcca accaattttt ctgcatcctt accagatacg ttgattgaat
    10621 aaatcccttc tggtatacat aatttttctg taagtagtac aatattctta cctgagaaga
    10681 cttctttctc catattacag tcaattttca actcacaatc tccatacata tatatagatg
    10741 acaaaatatt aagttgataa ccagatatta ttttagtcaa atccgataaa ttcactttag
    10801 gtataggaat atatatagaa agtacatttt ctttctcata tgattttata tatgtacaac
    10861 tttgaatctt ctctatccta tactctgcat cttcaagctt tttggcttct tcttccctat
    10921 attcttcttc tgctatccaa tatttgatat cttttaatgt atcttctaaa gtatttttta
    10981 gcaatgattt taacaactca cttagaccaa caatatgagt ctcactacag tagctattta
    11041 actctaaaag aagacgtgtt tcttctaata tattcacttt ctgtacgcca tcaccatatg
    11101 aaagttcttg tacaaactcc ataagctctt tcatattatt agtcctacta cataaatctg
    11161 tatacatctt atctaattga gtctttttat cctttagact atttatagaa gatagaatgg
    11221 aaatagaatc ttccatacct tttttgacac tttctatata aggaactaaa agtttttcta
    11281 ggtctttata ggttacatca acggcttttt gtatttctat tttacaagaa gcagtaagca
    11341 tcaatcccaa atctgttttt tcaaatgttt caggtagatt tttcatttca tccaacaact
    11401 tttctggctg tctatctagt ggattacata atttaataga tacaccatct gataatgcta
    11461 catttaataa gtacactaat tccttacaac cgtcgtaatc tttctcttga ctatctaggt
    11521 cttcttttgc tttttccaat atattcctta ttttttcttc tgttacatta ccgattagtg
    11581 ttttaggtat tttattgata agaaagaaga aattttcttt atactttgca taatcaccaa
    11641 gcatatcttt caaatttttg cctgtttcta tcaataatgt atgtctagag tccagtaagg
    11701 attgatagtc taaaataact accatccctt tcacctttga agatgtagaa atagtttccc
    11761 ttacaagcat agcaccagca atcatatact ctgctccacg gttatcaaaa aaacctgggc
    11821 aatcacataa tgaaaaattt ctatttgcaa tatctacaac ttctggacat aaagtcttag
    11881 aatatacacc atttccaatt tcgacagctg aatcttttgc agttatatat atttgtccag
    11941 tctcttcatc cgttttttct tccatcacgc aaccttttaa ataatttata caagtactct
    12001 ttccaacgcc tgaagcacct aagaataaca aaattgactt ttcttttaag tcatattttc
    12061 taagctcgtc tcttccttct tccaaaaggt ttacgatttc actataaagt ttatttgcca
    12121 tacatccatc cctttctata tttcggaaca atagccttga tatttttctt taataagatt
    12181 ctcttctacc tttgaaacag ctgttgataa cttagtattt ggagcattaa atcctccgtc
    12241 gtctcctcta tctccatatt cagcgtattc tcttgctggt cctgttttgc cttcattcca
    12301 acttccgcca ctaaattcta tatgatattt aattatacta tctaacttat aatcccaact
    12361 tgtaaaatat cctgtatagt aaacagtctt atctatacca cttggagaaa atgaaagtgt
    12421 attatatccg tgatagccac cacttcctcc atatccacct gaacctggtc taccatttgg
    12481 acctgcttct ccatctttca ctgttatatc acaatgatta attattctat ttttttgttc
    12541 ctctgagtct gaaatgaagt aaatattacc tttattacca gcatttccac ctcttccggc
    12601 atttccacca gctccacctt tgtcaccttt tttaccactt gtaccttttg caaaataccc
    12661 tttaaacatc tgtccatgga aactacttgt atatcctgca tcagctccat tacttccaga
    12721 atctcctgtt tcaccatttt taccatctat tcctttagaa ccatttcctc catttgcaat
    12781 cagtgttaaa cgataatttc taatttcttc tttaatatat aagtaaatat tacctgcatc
    12841 tctaccatct tcaccatttt tcccatacat agaactatct acaagttctc cgctctttcc
    12901 acttacatta atttttacat tactacctac atcaagattg ttacaagcaa gaataatatt
    12961 tttctctgat gcaaagtcca ttccaaggtt atcatccata taaatagtat ctttggcaaa
    13021 gaacataaat gtagaaacat tgtcatctac ttttctattt ttgaaatatt ccaatacact
    13081 actaattact aagtttggaa ttaatgctct tatttcaata cctttcttat cattaatatt
    13141 aattgttttt actataaatg gatttaaaat gtatttacca ataaattctc taattatctc
    13201 attaccttct tctccatatg cacttaatct tgttatactg tcttctaact cttcattttg
    13261 tgtaactgta acatttgtca aaattgaatt aaaatcactt acactatata cataatcctt
    13321 tttatttgca acttccatta atttttctct atttggtaat gtaaatacct gtttttgtac
    13381 ttcataagaa actaaaactt tttctaaatt ctttcttatt ataatgaagt tttgttccat
    13441 tatcttctta cttgcctttt ctataataaa ttccatatgt acagaaggta ataaaatttc
    13501 cccagttcca tgttctgtat atttacttaa agcatcaatt atatctaagt ttccttttat
    13561 cttattttgt aattccatgc aactatcttg taagaataag ccactttgtt tggctaatac
    13621 gttgataaat ctctctatag taagagttgt tgtactttcc aaccagtttt taaatacttt
    13681 tacaacctca tcatattttg ctatttcttg aatcattgtt atacttccaa taatactgat
    13741 aaaatcttct gtatacgcct taacataatc ttctaggcta gatacgatat tgttttgaat
    13801 ttcttttatc aacgtatcta aaactaatct tgcatctgca ctaattggat attggaatgc
    13861 tgatgtctta tctttaactt catctaattc tagtacttgc tttaataagc cttccctctc
    13921 gtctgattca agtggcttac aaagatgaat atttttacca ttatctttta gcaattcttc
    13981 aaataaccaa gctttttcct ctatattact atctaaattt tcacataatt gttcatattt
    14041 tctttttata acattatata tttgtttttc tgttcttcct aagaaacttt ttgaaatgaa
    14101 aaaagttata ctgcccctaa aattgtcttt atgaagacac atatttaact gttgaaacag
    14161 gtctagtact tttgtaagtc tagaatctaa tatatctgct tctggtctga acctcccatg
    14221 actaaagtca cagggttcct gcttcacaga attttgcata ctaaaatatg tcttactaat
    14281 tctccacagg ccatccccgt agttcctacg gttcttacat aagttattta ttttgaattg
    14341 ttattagtct taatccttct tttaatatat ttatacttgc atttatatct ctatcgtgag
    14401 tttcattaca gctaggacaa atccattctc ttatacttaa gtccttcact tcctcgtttt
    14461 tatacccaca tttattgcat atttgtgaac ttgcaaagaa tttacctacc tttacaattt
    14521 gtctaccatg ccaattagcc ttgtatttta attgacgaat aaattctgac catgatacat
    14581 cagaaattaa gcgagatagt ttacgatttt taatcatatt ctttacttgt aaatcttcta
    14641 tgcaaataat atcattctct tttattaatt tagtagatag tttttgtaga aaatcatttc
    14701 tttgattggc tatatgttct tgaagtcttg caacttttaa tcttgcttta tttctattta
    14761 aactaccgat tgtttttctc gataattctc tttgtaattt agcaagtttg tttaatgact
    14821 tcttaagata cttaggattt tctataaagt ctccacaact tgagatacaa aattctttaa
    14881 ttcctaaatc taaacct
//
LOCUS       DAMJWO010000094        14536 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.097, whole genome shotgun sequence.
ACCESSION   DAMJWO010000094 DAMJWO010000000
VERSION     DAMJWO010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14536
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.097"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..1028)
                     /locus_tag="PC366_003146"
     CDS             complement(<1..1028)
                     /locus_tag="PC366_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HDF2578638.1"
                     /translation="MKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVMYDEKTKNIDKF
                     KSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYTFGN
                     LDLTCFNNTDMRSAKKNNHPRFVNNIRDLFVDIKEKYINCGMRCMNYISLKNLLEFVN
                     LEFSGDAHDPLNDAYNLFILDEAITNNVDIQNLLIIRDIIRPPFNDINSNLDNCFNKF
                     KESLYKKEGNYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEIMKDINKKMDTIDKLKDI
                     EEGYFYLLEDVYLDMKDVLEDLMLYRMNEDEYKYEIKNIIKMFDEDLDNEKIYINKCN
                     NLNVVNKI"
     gene            complement(1076..1936)
                     /locus_tag="PC366_003147"
     CDS             complement(1076..1936)
                     /locus_tag="PC366_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HDF2578639.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKSI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            2215..2424
                     /locus_tag="PC366_003148"
     CDS             2215..2424
                     /locus_tag="PC366_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HDF2578640.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            2424..2690
                     /locus_tag="PC366_003149"
     CDS             2424..2690
                     /locus_tag="PC366_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HDF2578641.1"
                     /translation="MKDSSRAELMRKVQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            2719..3291
                     /locus_tag="PC366_003150"
     CDS             2719..3291
                     /locus_tag="PC366_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF2578642.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(3525..4715)
                     /locus_tag="PC366_003151"
     CDS             complement(3525..4715)
                     /locus_tag="PC366_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF2578643.1"
                     /translation="MNFNQKRIAASIMATAIIMPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKEGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTNENVENSSNDLVKGTKVVTAKSLNVRTGPGTSHSKIATL
                     SYGTEVGSISESGGWTKVSYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGADSVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSAGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLVFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(4975..5406)
                     /gene="dut"
                     /locus_tag="PC366_003152"
     CDS             complement(4975..5406)
                     /gene="dut"
                     /locus_tag="PC366_003152"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HDF2578644.1"
                     /translation="MYNLKVKKLNDDAIIPNFAHKGDAGMDLYSIEEVVIPPGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIVKPIYDINIEEVKELSDSERGKGGFGSTGF"
     gene            5519..7747
                     /locus_tag="PC366_003153"
     CDS             5519..7747
                     /locus_tag="PC366_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HDF2578645.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFVPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEYEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAEAGEYKGKYVKGKESKFDTLEDANKIIASITSETGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKSLSKDEQLVYDA
                     IKDRFVANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKISQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEAYTFDSKTKKFTKTKEKKQKKDVTNT
                     EKEVAISKDSNNKKEVKNGDENQSLGKCPICQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDATLKYDKNPDTGYFNWKIEF
                     DN"
     gene            complement(7858..8343)
                     /locus_tag="PC366_003154"
     CDS             complement(7858..8343)
                     /locus_tag="PC366_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2578646.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFKESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFKLFDAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            8595..9818
                     /locus_tag="PC366_003155"
     CDS             8595..9818
                     /locus_tag="PC366_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HDF2578647.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTKESEPEKPIAVSVQKAVGGEIE
                     NTNSFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPELENSVKQSK
                     ASLDLAKASYSSATGGSLEAQVNQAKTALDNAKIQYEESQRNYDNNKILYEQEVISLD
                     QFKKIEFSLEQTKQQLDSAQRAYDTATSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTSPVDGTITAKNFDSKEMITQSQPAFIISNPNILEVDLNVAESDIGKFKKDGNVD
                     VIIEDQRILGKIDYVPSVVDPQTSLYPVKVLVNNANNKFKAGMSAQVNLSIEKENGAV
                     TVPKKAIFEENGKKYVYIATKDNIAKKHLVQTGIVTEDKIEIKSGVSDKDTVIIGGIS
                     LISDGTKIFPVEKEK"
     gene            9822..12956
                     /locus_tag="PC366_003156"
     CDS             9822..12956
                     /locus_tag="PC366_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HDF2578648.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQVSQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGEKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     SNLLISAVIAFIVIFAFLKSVRASLVVAVAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSLDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTEGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSRGKNSQKMQEKDSPIFDK
                     VSEAYKKLLSVCLRHQRLVVISSLLIFVASLFGMGFIGMDFMPAADKGELSISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNSKASIAIELESQKNRKRTTDE
                     IEKEIIDRVATVPDCKINVSQNSSVMGGAGGADFTLEMKGPDLDVLKILGKEAEKEFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGVNTAEIAGMLRTAINGDSVTTATIDD
                     YKVDVNLKFKADTIDSLEDIKQLKVNSATGKEVPLGAFSDIKMADGLQSISRTDGDFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGETEMMNESMASLGFSMVIAI
                     ALVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTVSTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGSI
                     KRKIIKKPKLKAKV"
     gene            12990..14288
                     /locus_tag="PC366_003157"
     CDS             12990..14288
                     /locus_tag="PC366_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HDF2578649.1"
                     /translation="MSKIVAIGCGVGIITANLIPVYADNNTSSINNVDNSILSDSNKR
                     TSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFPYDQI
                     GLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMKLKKD
                     LGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEYRFES
                     FRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPNLTRPVAPTKP
                     EQGNLTDDEYKVLMDKYEKDYKRYEKEVEAYNLERQTYAAGLTTYANYLQQKFNTENG
                     LVTLEDSKKALKKGLIDSYAQLLALEDTIQITKKQLDLSEKQLKNTKLRYDLGLITLT
                     DYKKQVVSNQDAKNSYDTLIVNYNSLKNGIEKPWILNTGK"
BASE COUNT         5364 a         2124 c         2134 g         4914 t
ORIGIN      
        1 tatatcttgt taacaacatt taagttatta catttattta tatatatttt ttcattatct
       61 aagtcttcat caaacatttt tattatattt tttatctcat acttgtactc atcttcattc
      121 attctataaa gcattaaatc ttctaataca tctttcatgt cgaggtacac atcttctaat
      181 aaataaaaat agccttcctc tatatctttc aatttatcta tagtatccat ttttttattt
      241 atatctttca taatttctaa attttgtata tttacatcta tgattgttaa taagtacatt
      301 ctcacagttt ttattatttc aacagaaaaa tctacaatat tataatttcc ttctttttta
      361 tataatgact ccttaaattt gttaaaacaa ttatctaaat tagaatttat atcgttaaat
      421 ggtggtctta ttatgtcacg tattattaaa agattttgta tatctacatt atttgtgatt
      481 gcctcatcca aaataaataa attatatgca tcatttaatg ggtcatgggc atctccacta
      541 aactctaagt taacaaattc aagtaaattt ttcaatgata tatagttcat acatctcata
      601 ccacaattta tatatttttc ttttatatct acaaataaat ctctaatatt atttacaaac
      661 cttggatggt tatttttttt agcacttctc atatctgtgt tattgaaaca tgtcaaatcc
      721 aaattaccaa aagtatatat tcctttaata tcagaaaata tgccaagcca ttttttaaat
      781 tttctcatga cctcttcata acttggtgca ctcttcaatt cttcagaaga tatatgtgtt
      841 aattcttgta tatgaggata taactcctca ttacttactg gtcttattaa agatttaaat
      901 ttatcaatat tttttgtttt ttcatcatac ataactgctc cgattgcaat tatatcagaa
      961 ttaaatactg ctctttttga tttagaattt ggcatattca tttcaaaatc tatatatact
     1021 cttttcaata taaacaccct ttccaattgt ttatagtgat tctttttaac tatttttatt
     1081 caaaattttc taagaaagaa tgtttctccc catctttttg ccaaccaagt actgaatcaa
     1141 gatttacatt ttctgctgcc ttaaatatag atttttctac atttttaaaa tttgattcta
     1201 agctctttat taagtctttt atctcatatc ttttattacc tgttttttta gcagcaacca
     1261 tacatgcaca atttaatggc catataccac tattttgaat aaatcttata atatgttctt
     1321 ctcttatata ataaagtggt cttataattt ttataccttc aaaattagta gaattaagtt
     1381 taggaagcat tgttttaaaa tttccagcac acaataagtt aagcattgtt gtctctatta
     1441 catcatcata atgatgacct aatgcaagtt tgttacaccc taattcttct gcctttgaat
     1501 ataatgctcc tctcctcatt cttgcacaca tatagcatgg ataatctttt gctatttcat
     1561 ctgctatctc aaatattctt gaatcaaata aatgtattgg tatatttaga tactcacaat
     1621 tatctataag taattgtctt atatttgcat ggtatccagg gtccatagca ataaattcaa
     1681 catcaaaatt aacttgtcca tgttttttta actcttgaaa cattttagcc ataagaatac
     1741 tgtcttttcc accagaaatc gctacagcta tcttatcccc ttcttcaacc aatttataat
     1801 ctcttattga cttcataaac ttagaccata aattttttct atatttcttt attatacttt
     1861 tttctatatc tcttactgga agtctttcct caaaaggaac tataatttca cagccttttc
     1921 ctgatagttc actcatctaa tcacctcgta tatttatgta tatttatgtt aataatattt
     1981 tacaaaaaag tctaccttca tccacaaaat actataattt ttactttaat tttactaaat
     2041 aatttatagt ttacaataac acataaactt ataataacat aaataacctc tttcttttat
     2101 tatctttttt atttttctca tttaatattt tattattagt aacgattttt aaatgattga
     2161 atattataca ctagatagag ttacctatct atttacaaca aggaggtttt catcttggaa
     2221 aataagacta gagatatcaa aaaaaattgt ggtccatctt tggctagacc atacattaat
     2281 aatcaaattt tcacagaaat gtactgcctt tctgatgcat taaaatttgg aactatattt
     2341 ccagaactaa acttactaga gtctgaaatg tacaacaaag aattatatgc taagccaaaa
     2401 aaatatagag gaggtagaag ataatgaaag actcatctag agctgaactt atgagaaaag
     2461 ttcaggaaac atcttttgca tgtgttgata tgaacttata tttagacaat caccctgatg
     2521 ataaaaatgc tatcaacact tataattcat tatgtaatca atttgcgcaa gctagatatg
     2581 cttacgaaaa taaatacggt cctttaacta actttgggta tgctccaagt agatgccctt
     2641 ggcaatgggc tgaccaacct tggccttggg acagagaatt taattattag acatcaagta
     2701 ttggaggatt gaaaattcat gtggatatat cagaaaacta tacaacaccc agttaatata
     2761 aaaacttgtg accctagaat ggctaaattt cttataactc aatttggtgg gccaaatgga
     2821 gaacttgctg catctttaag atatttaagc caaagatata caatgcctac tggtaatatg
     2881 cgtgcacttt taacagatat tggtacagaa gagctagctc acgttgagct tatatgtact
     2941 atggtttatc aattaacttc tgatgcaagc ccagaagagt taaaagctgc aggtcttggt
     3001 tcaaactatg ctcaaaatgg atatggaatt tatccaacag attcaaatgg tgttccattt
     3061 gatgtaagac ctatagcagt tatgtcaaat cccgtaaccg acttacatga ggatatggca
     3121 gctgaacaaa aagcacttgc aacttattat caacttataa acctaacaga tgacgttgat
     3181 gttatagatg tattaaaatt cttaggtcaa agagaaataa ttcactatca aagatttggt
     3241 gaagctttaa tggatgctta cgagttagaa gaatctcaaa aaatgttcta aaatttttat
     3301 ttgtataact attattattt gataatttat aatttactgt tgtgttaaaa tttataaaaa
     3361 atataaatat aatttatttt ctataaacag agaaaataaa taaaaagcag gtatcaatca
     3421 aatagtaaca tgtattatac tatacattac tatcaatatt gtacctgctt tcatattata
     3481 agcaataaag aaaaatctat ttattaggtt ttataataaa acaattataa aactcttctt
     3541 gcatttacat atctacttga atagtagcta ctatttatat tagatattgt tacttttttt
     3601 gatgaacctg aagatgcatg tatcatatct ccatttccta tgtatattcc aacatgactt
     3661 acagaaccat tatttgaacc ttgtgtatca aagaatacta aatctccact tctaaggtct
     3721 cctctattta catatgttcc atacttactt tggtctctag atactcttgg tatactaact
     3781 cctgcagatt ttttcataac gtactgtgtg aatccagaac agtcaaaact atttggacct
     3841 tctgctcccc atacatatgg ttttccaagt agtgtctttg caaaacttat tacactatca
     3901 gctccttgac ttggagaatt agtcgaataa gatggaattg aagtatcaac agaacctttt
     3961 tcagcaaggt attgacttga cacatatcca gtttgattgc cataacttac ttttgtccat
     4021 cctccacttt cagaaatact tccaacctca gtaccataac ttaatgtagc tattttagaa
     4081 tgacttgtac ctggtcctgt tctaacgttc aatgactttg ctgttacaac ctttgtaccc
     4141 tttacaaggt catttgaact gttttcaaca ttttcatttg tagagtcatt tacactagtt
     4201 cctaaatatt tacttgaaac ataacctact ctaccattag aacttatttt tgaccatcca
     4261 tttgactcag atatgtatcc gacttcagtc ccatatccta gtgttgatat tttagaacta
     4321 cttgtacttg gtcctgttct aaaatttaat ccttttgctg ttacaacttt tgtcgactta
     4381 actgaagtat cactactttc attgctactt ccaaggctat ttattgctac ataatttcca
     4441 tgcacataac ctgtgtttcc attatattta acttttaccc aagaaccttc ttttcctacg
     4501 tactcaactt tatcaccttt gtaaagtttc cccattgatt catggtttgt acctggtcct
     4561 tttctaaaat ttaccgcatt ccctgttatt gttctgcttt ctatactcac actctctact
     4621 tcagactcat tagcatatgc taaattcccc atagtaggca ttattatcgc agttgccatt
     4681 atactggctg ctattctctt ttgattaaaa ttcataactt tccactcatc tcctcttttc
     4741 tactatcttt atttcacttc aaaatataaa agaaataatt gacactatta aaatatcaat
     4801 tatttctttt atattaatat tattacaaat ttgtaactat ttgtctatag taatatttgc
     4861 ttaccataaa ttaccatgta taaattttaa tcttcaatag cctgtaattt agtaatatag
     4921 ccatctttta ccttttttaa aaatggctat attttttaac ttttttgtaa ctttttaaaa
     4981 tccagttgag ccaaacccac cttttcctct ttcggagtca cttaattctt ttacttcttc
     5041 tatgttaata tcatagatag gttttactat catttgagca attttcatat gcttttcaac
     5101 cttaaaatca tttttcccat gatttattaa tataatttta agctctcctc tgtatccttc
     5161 gtcaatagtt cctggtgtat ttaatacagt aacagaatgc tttaaggcaa gcccacttct
     5221 aggtcttacc tgcgcttctg tcatagtagg aagctctata catatcccag ttttgataag
     5281 tttagtctct ccaggaggta ttacaacctc ttctatagaa tacaaatcca taccagcatc
     5341 acctttgtga gcaaaattag gtattatagc atcatcattt aattttttta cttttaaatt
     5401 gtacatctta tatctccttt caactttcta taaatattat aacttaaatt tcgacctctt
     5461 gaagtttttt atttttttgt ggtaatataa ttattagtgt tttaaaggag gattttttat
     5521 gaaacttgta cttgctgaga aaccatctgt ggcaaaaact atagcatcat ttttaggtgc
     5581 aaagaccaga caagatggtt actttgaagg aaatgattat ataattactt atgcagttgg
     5641 acacttagta tcattatatg atatgaagga ttatgataaa gataaatact ctggctcttg
     5701 gaaaatgaac aatttcccat ttgttcctga ggataagttt aaatttaaga ttgatagttc
     5761 taaaactaaa caattcaaca ctgtaaaaaa gcttttgaat agaaaagatg tagaatatgt
     5821 aataaatgcc actgacaatg accgagaagg agaacttata gcatttttaa tatttttact
     5881 ggcaaaaaat aaaaaaccag taaaaagaat cttggtaaat gaatggacac cagaagatat
     5941 tacaagaggt ataaaaaacc taaaagatga atatgaaatg agaaatcttc aagctgctgg
     6001 atatactagg cttattactg actggttgat tggaataaat ttcacttctg ttgctacatt
     6061 gaaatatgga aatgggaaac tattaaacat aggtagggta attcttccaa cagttaaatt
     6121 agtctatgat agagatatgg aaatactaaa ctttgttcct aaaacttatt atgaaataga
     6181 aggacatttt aaagctgaag ctggtgaata taaaggtaaa tatgttaagg gtaaagaaag
     6241 taaatttgat acacttgaag atgcaaataa aattatagct tcaattacat ctgaaactgg
     6301 taaaatacta gataaaaaag ttactatgtc aaaggaatat gcaccaaaac tttttagttt
     6361 gacatcactt caaggatata taacttctaa gtattccaat tttacatctg ataaggtttt
     6421 aaatgtctgt caatctctct atgagggtaa tggtaagggt ggatacataa cttaccctag
     6481 aactgattcc attttcttag aagaaagttt ggcttcaaaa gcttctcaaa ctttagataa
     6541 attaaaggtt ggtcttgaat atgaaaataa aattaaattt tctaaaacta aaagagtttt
     6601 tgattcttct aaagtagact cccatagtgc tataattcca acttatataa ttccaaaaag
     6661 tttatctaag gatgaacaat tagtttatga tgccataaaa gatagatttg tagcaaactt
     6721 tatgcctcct gctgaatatg agaatacaga aattaagact gaagtagata attgtacttt
     6781 cttaacaaaa ggtaaagtgc ttaaatcaaa aggatacctt gaggtatata ataaggaaga
     6841 aaaaaacgat ttacttccac ttgtaaataa agatgatgtt gtagatgtgt tagaaataaa
     6901 accattaact aagcaaacta ctccacctaa accatatact gaggacaccc ttttaaaggc
     6961 tatgaaaaat tgtggtaaaa atgtgcctga agaagataca acagtgctat ctggatattc
     7021 gattggaaca tcagccacac gtgctgatgt gttaaagaag ataagtcaag tgggctatgt
     7081 aaagaaaaaa gggaaatctt attctataac agaccttggg aaaaatttag ttgaaatttt
     7141 tcctgttaaa gacttatttg atgtagatta tactggaaaa cttgaaaaaa gtttaagcga
     7201 tattcaaaaa ggaaagtata caagaaaaga atatcttact aatatcatta gttttatata
     7261 tcaaaatgtc aatattataa aacaagatgc ttcaaaaaat ataaacacag aagcatatac
     7321 tttcgattca aaaactaaaa aatttactaa aacaaaagaa aaaaaacaga aaaaagatgt
     7381 aactaatact gaaaaagaag ttgctatatc aaaagattct aataacaaaa aagaagttaa
     7441 aaatggtgat gaaaatcaat ctcttggcaa atgccccatt tgtcaaggtg atgtactaga
     7501 atttgacaaa ggctttgctt gtaaaaatca taaagaatgt aaatttgtta tttggaaaaa
     7561 tgataagtat ttaagtcttt ataaaaagaa agttaacaaa acaatggtca aaaatatttt
     7621 aaaaaaaggt gaaactaaag taaaatcttt aactgctaaa aacggtaata aatttgatgc
     7681 tacattaaaa tatgataaaa atccagatac cggctatttc aattggaaaa tagagtttga
     7741 caactaaata ttcataagaa aagaaatagc agtagtataa taatctatat tatattactg
     7801 ctatttcttt tcttatgaag ttttaacttt tttaatagtg acttttacaa tcacactcta
     7861 acctaatttc tttactattt ctgataactt taatgtatgt tcatctaata aagttagttc
     7921 ctcttcagaa agattagata atttttttac tagagattct ttgagaatag cttttactgc
     7981 atcaaataat ttaaatgctt tatctgttaa ttcaacccta agaatccttc tatcttttgg
     8041 gtcaggaaat ttattgacta aaccatgttc cactaatctg tcaataatcg gagtcatatt
     8101 tgattttaaa attcctaaat tagaagctat ttgagaaatt gatgatgaat ttgatgtcat
     8161 aagataaaga attaccttag catgtgatgg agccattgga cattcttcaa aataagcttt
     8221 cattatatca gagttatttt gaaacttttt taacaaatcg ctttctttaa atatattatt
     8281 ttcaagcaca aataaaaaat ctaaaaaaga gtccgctatt ttaagtatat tgttgttatc
     8341 catatttgta acatcccttc aatagataat ataataaaac attgttgttt aatatagtat
     8401 aaattataaa ctattaataa atttaaaaca agaaaaagtt attgactcat aataattata
     8461 aatttataat caaattagag aattataaat tgccaataaa gggaagtttt ttaattagtc
     8521 taaaactaaa cttaaattat aagacacttt aaattctaca acaagctagt gtgcaatata
     8581 taataggagg agatatgaaa agatatttaa tagttttctt aatgtgtagt tcactgtttt
     8641 tagttggatg tggaaaaaca aaagaatctg aacctgagaa accaatagca gtttctgttc
     8701 aaaaagcagt aggtggagaa attgaaaaca caaattcttt ctcaggaact acaaaagtta
     8761 aagatgaaac agctgttact gcacagactg ttggcacagt tcaagaagtg tatgtaaaac
     8821 ttgggcaaaa tgtaagaaaa ggagatgaat tattgagtat aagcagtcca gagctagaaa
     8881 atagtgtaaa gcaaagtaaa gcctcactag atttagcaaa agcaagttat tcaagtgcca
     8941 ctggtggttc attagaggca caagtaaatc aggcaaaaac agctcttgac aatgcaaaga
     9001 ttcaatatga ggagtctcaa agaaattatg acaataataa gattctttat gaacaggaag
     9061 tcattagttt agaccaattt aaaaaaatag agttttcttt agagcaaaca aaacaacagt
     9121 tagattctgc tcaaagagca tacgatacag caacttcaaa aagtatacct caagctaaag
     9181 cacttgctaa aaaacagctt gaccaagctc aagtatcata taatttagca atgagtaatt
     9241 tagacaaatt aacattaaca tctccagtag atggtacaat aacagctaaa aactttgatt
     9301 caaaggaaat gataacacaa tcacaaccag cttttattat ttctaatcct aatatactag
     9361 aagttgattt aaatgtagca gaatcagata taggtaaatt taagaaagat ggaaatgtag
     9421 atgttataat tgaagaccaa aggattttag gaaaaataga ttatgtacct tcagtagttg
     9481 accctcagac atctttatat cctgttaaag tacttgtaaa taatgcaaac aacaaattta
     9541 aggcaggtat gtctgcacaa gtaaacttaa gtattgaaaa agaaaatggt gctgttacag
     9601 tgcctaaaaa agcaatattt gaagaaaatg gtaaaaaata tgtatacata gcaacaaaag
     9661 acaatatagc aaagaaacac ttggttcaaa ctggaattgt aacagaggat aaaatagaaa
     9721 ttaaaagtgg tgtaagtgat aaagatacag tgattattgg aggaataagt cttatttctg
     9781 acggaactaa gatatttcct gtagaaaagg agaagtagac tatgaattta acacagactt
     9841 ccgttaaacg tcctctcaca atcataatgg tctttttagt attaatagtt tttggtggta
     9901 ttggatataa aaaaatgtca ataaatctaa tgcctgatat agaaatacca gttgtaatgg
     9961 tcatgactac ttggacaggt gctggtcctc aagacgttga tgaacaagtt agtcaaaaag
    10021 ttgatgaaag tttatctgcc gtttcaaatg taaaatctac tatatcaagt tcacaagaaa
    10081 gtgtttctat ggtagttgct cagtttgaat ttggaactaa tttggatgaa ataatgaatg
    10141 atgttaggtc taaagttgat gcattacaga ccagcctccc agatgatgca gcaaaaccaa
    10201 cagttttaaa gctggatatg aatgcacagg ctataggtca acttgtcata tctggaggaa
    10261 atgaaaatag ttcacaagcc ttaagaaaat acgctgaaga tgtaattcag cctaaaatag
    10321 aatccataga tggtgttact tcagcagacc ttaaaggtgg agaaaaagca caggttaatg
    10381 taatagctga cccagctgtt ctttcaaatt atggagttag tttatccact ataaaaggtg
    10441 tcttatcctc tagtaataaa acattccctt atggttcaat tactcaaggt gaggataaaa
    10501 tagttttaag agcaattgat aaattagaat ccctagatga tataaaacag attcaaattc
    10561 ctgtaaaagg aggaaataca gttagattag ataatctttg tagtgtagat tatggatatg
    10621 cagacaaaga tagtatttat agatacaatg gaaaagacag tttggtaata gatatttcta
    10681 aacaacaaga tgccaacact gtaaaagtta tgcagagtgc atacaaatac gtagatgaat
    10741 tgaataagga aaatcctcaa tttaaaatta aaattgctaa tgatacaagt tcatacataa
    10801 gtgaatcaat aaacagtgta atgagcaact tgcttataag tgctgttatc gcatttattg
    10861 taatatttgc tttcctaaaa agtgtaagag cttcactagt tgttgcagtt gcaataccaa
    10921 tttctataat aggtgctata gcaattctct actttactgg tgaaagttta aatcttatta
    10981 ctgcaagttc attggtaatt tcagttggta tggttgttga taatgctaca gttgtaattg
    11041 aaaatatatt taaatatagg aaaagtggca gattgagtct tgatgattgt gctattgagg
    11101 gaacaagaac tgtaacaaat gcaatacttg catcaacatt gaccacgata gcaatattct
    11161 tacctatcat gtttacagaa ggtatagcta aaataacttt tggggcatta ggtaaaacac
    11221 taatagcttc actagcattc tcctttatag gtgcaattac actcgttcct agtgtatttg
    11281 caaaattaag cagaggaaaa aatagtcaaa agatgcaaga aaaagatagt cctatatttg
    11341 ataaggtaag tgaagcatat aaaaaattat taagtgtatg tttaagacat caacgcttag
    11401 ttgtaatatc aagtttactt atttttgtag cttccttatt tggaatggga tttataggta
    11461 tggactttat gcctgcagca gacaagggtg aattatctat ttctatagaa cttccaaaag
    11521 gtcttagcct agaatccaat gattactatg tatctatgac tgagaaaaaa gtctcagata
    11581 ttccagaaat taaaacttta ataacaactt tgacatcaga ttcaaataat agtaaagcaa
    11641 gtatagcaat tgaattagaa tctcaaaaaa atagaaaaag aactactgat gaaatagaaa
    11701 aagagataat tgatagagtg gctactgtac cagattgtaa aataaatgta agtcaaaaca
    11761 gtagtgttat gggtggagct ggaggagcag acttcacatt agaaatgaaa ggtcctgatt
    11821 tagatgtatt aaaaatactg ggaaaagaag ctgaaaaaga atttagctct ataaaaggat
    11881 ttagaaatgt tgaaacttct cttacagata caacacaaga agctcaattt actatagata
    11941 aacataaggc tcaagaatat ggtgtaaata ctgctgaaat tgcaggcatg ttacgtacag
    12001 caataaatgg tgactccgta accactgcta ctattgatga ttacaaagtg gatgtaaacc
    12061 taaaatttaa agcagatact attgatagct tagaagatat aaagcaacta aaagtaaact
    12121 ctgcaactgg aaaagaagtt cctcttggtg ctttttcaga tataaaaatg gcagatggtc
    12181 tacaatctat atctaggact gatggagatt tttctgtaaa tataactgct acacttgaca
    12241 atttagatgc tggtactgct acaaaactag cactagaaaa aacgaataaa atggtaattc
    12301 ctaaagatta ctctataggt gttggtggtg aaacagaaat gatgaatgaa tctatggcaa
    12361 gtcttggatt ttcaatggtc atagctatag cattagttta tatggtaatg gtagctcagt
    12421 ttgaatcatt tagtaaacca tttataatca tgttctgtgt tccatttgca ttcgttggag
    12481 ttgtgctttc gcttctagtt agtggtcaaa gtttaagtac tgtcggtatg ctaggtataa
    12541 tcttacttat cggtattgtt gttaataatg gtatagttct tattgactac atagagcaac
    12601 ttagaaaaac aaatcgtaac aatgatttaa ttggtttggt ttcaattggt tgtgcagcaa
    12661 gattaagacc agtcttaatg actacagcaa caacaatttt aggtatgttg ccaacagcac
    12721 tatctcttgg tgaaggtgga gaaactatgc aaccactagc catagttata atgggtggtc
    12781 taactgtatc tacacttata actttggtgc ttatacctac tatatactta atatttgata
    12841 aatgggaaaa taagttttca gacaaaatgc ctaaaatatt tggtaagata acagataaaa
    12901 taggaagtat aaaacgtaaa ataataaaga aaccaaaatt gaaagctaaa gtttaaatag
    12961 aatggagggt gattgtattg aataaaaaaa tgagcaaaat agttgcaatt ggctgtggtg
    13021 ttggtataat aactgccaat ttaatcccag tttacgcaga taataatact tcttctataa
    13081 acaacgttga taattctatt ttaagtgact caaataaaag aacatctgaa aaggaaattt
    13141 tgactgctag agaagctgtt agtgctgcac ttaaaaatag tgaaaaatta aaaatgaaat
    13201 cagaagaaat aaaaatgtta aaagaaaagt tagaagtaca agatgagttt gatagtttta
    13261 ctggaagtga caactcgttt ccatacgacc aaattggact tcttaaaaat caaagtgaac
    13321 aggctaaagg ctttatggag gaccaaatag caaatgatat tactaataaa tttaacgatt
    13381 tagtttcaag agaaaatgag ctagataaga taaaaaacaa tcttgaaata aaaactaaag
    13441 aaattaaaga tatgaaatta aaaaaagatt tagggttagt aacatcttta gaaactgaat
    13501 cagctgaact tgaacttcaa acactacaaa atactcaaaa agctaaactt caagaactaa
    13561 aaaacaatca agactatttt aagttattga ctaatataga tttaaataat tatcaattgg
    13621 ataaagaata tagatttgaa tcttttagag taggtggctc agttgattca tatatggaag
    13681 gtaaggttaa tgaatattta aaatacgacc aattgatttt agaacgtaca gaagaaagct
    13741 ttaatgataa agatgagaac aaagcagatt taccagatag acctaatctt acaagaccag
    13801 ttgctcctac aaaaccagag caaggtaacc taactgatga tgaatacaag gttcttatgg
    13861 ataagtatga aaaagactac aagagatatg aaaaagaagt tgaagcatac aatcttgaaa
    13921 gacagactta tgctgctggc cttactactt atgcaaatta tcttcaacaa aaatttaata
    13981 ccgaaaatgg tctagtaaca ttagaagaca gtaaaaaagc tcttaaaaaa gggttaattg
    14041 atagctatgc tcaattactt gctttagaag atacaattca gattactaaa aaacaacttg
    14101 atttatcaga aaaacaatta aaaaatacta aattaagata tgatttagga ttaattactc
    14161 taactgatta taaaaaacaa gtggtaagta atcaagatgc taaaaatagc tatgacactc
    14221 ttattgtgaa ttataactca ctaaaaaatg gtatagaaaa accttggata cttaatactg
    14281 gaaaataatt ctggtaaata gaaagattac tttaacatac gtttgattaa aaaatagtta
    14341 tgcacactcg tggctttagt catggaagat tcagaaggca aataatagaa atagattagt
    14401 aaaaatatat ttacttataa aactgtatac ttttatagag gctatctcaa aattggatat
    14461 gtccctgtca agtagacaga cttaaaaaag gctatcttta tgcggaatga gttcgatatt
    14521 caatcgaact cattcc
//
LOCUS       DAMJWO010000095        14117 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.098, whole genome shotgun sequence.
ACCESSION   DAMJWO010000095 DAMJWO010000000
VERSION     DAMJWO010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14117
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.098"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            436..1329
                     /locus_tag="PC366_003158"
     CDS             436..1329
                     /locus_tag="PC366_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HDF2578650.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELRNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     ILKLEEGDSHHHSNCGCGGNK"
     gene            1329..2723
                     /gene="gltA"
                     /locus_tag="PC366_003159"
     CDS             1329..2723
                     /gene="gltA"
                     /locus_tag="PC366_003159"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HDF2578651.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLNINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKTKVNA"
     gene            3089..5308
                     /locus_tag="PC366_003160"
     CDS             3089..5308
                     /locus_tag="PC366_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2578652.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIEASKRELENYLEVNISLLKALSQDDRFSNGETSLIEKGKLLRPYQKEYNLFMIGI
                     TDTKGNASSTYRENVNSIKDKPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIVKN
                     NEMIGTIFASFYFQDVNNLISRSNFDDSIKFLMIDKDYTIISHPNKKYVNDKSKMLDL
                     EGNIIGTTKSEILKNINKKCQGDFLSWDNWRLYNVKYTNIKWTNWTLVSKCNIFKNFK
                     NLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIACNTEDELLNRLSKINKEICNLNTTNSSKYKIVMSSGIYKITKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEDTRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LDDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLKEIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            5455..6201
                     /locus_tag="PC366_003161"
     CDS             5455..6201
                     /locus_tag="PC366_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578653.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIEKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVVLDGYDVSKLKGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIMLPLTLEGASIKDMNIQTKSISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PTILLADEPTGNLDSKSTDDVLKLFTRINKEQNVTTLMVTHEVYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            6201..8081
                     /locus_tag="PC366_003162"
     CDS             6201..8081
                     /locus_tag="PC366_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2578654.1"
                     /translation="MDFRKFAYNNIVRNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     TKSGMQSGSTAFMALMTSELTILGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTEIYFPVKAILLTIVS
                     FMILFLITGPMSLKLLRKKSILELLVGTKKPKKEIKSSRLFGIIGVICLILGYAMILF
                     GNKLKINGGMYTTALLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLIYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGEASKNNFPMVYSYFSEHNNEKEYEE
                     LQQIREAIKGYDYKELSFPVLKYNREVLLSVKNYNKLSKELGLDKISSKLEKYEGIII
                     PSSNSQEHINSLKQLKNYSIKNLNIEVKKSKNKIIFPTGLFSKVVVISDDLYDEVKGE
                     FSKINFHGFDYKNWQSSAKITENLKEKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEIEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFRLENLGILLLISSIYSLYFYLLKKIYTRKVWF
                     FD"
     gene            8200..9591
                     /locus_tag="PC366_003163"
     CDS             8200..9591
                     /locus_tag="PC366_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2578655.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAILTIGYYIS
                     GKSNLRFSKSNLKLDKKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLVVATIILCMGMV
                     VVMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            9698..10738
                     /locus_tag="PC366_003164"
     CDS             9698..10738
                     /locus_tag="PC366_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDF2578656.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISIDSSVNKVEKA
                     VEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDDSL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            11227..11880
                     /locus_tag="PC366_003165"
     CDS             11227..11880
                     /locus_tag="PC366_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDF2578657.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFINKFMEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVSASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKASEKIHGIIDGMKF"
     gene            11956..12165
                     /locus_tag="PC366_003166"
     CDS             11956..12165
                     /locus_tag="PC366_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578658.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNIVMIDDGTGTLKQAVF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(12305..12871)
                     /locus_tag="PC366_003167"
     CDS             complement(12305..12871)
                     /locus_tag="PC366_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HDF2578659.1"
                     /translation="MMNNELNTIILETLNNADITSNDIPSIDLYMDQIISLIDNKLSP
                     NKRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRI
                     LHGVYEKDNFSEKDLVSCYEKFMLIKENQRKNIPDFIESNFENISINPENKDDLLIAL
                     LSLTSMADQLKNISEKLVDRYFPDITKK"
     gene            13032..13685
                     /locus_tag="PC366_003168"
     CDS             13032..13685
                     /locus_tag="PC366_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HDF2578660.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVTLQETSLL
                     MIVSVSVFGLSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
     gene            complement(13843..14019)
                     /locus_tag="PC366_003169"
     CDS             complement(13843..14019)
                     /locus_tag="PC366_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578661.1"
                     /translation="MYKYDDYVNLTNDLDLPVEIRNKCVRIVSVSENLEDIIIVHKFK
                     LYVVNEKYIKGIME"
BASE COUNT         5533 a         1394 c         2370 g         4820 t
ORIGIN      
        1 tatataatat gaaagctggt attgcaatag attaaagcct tatacacgtt tagtttttaa
       61 agaaattagt gttattatga aaacctaagt taatttatta aataaataat tgaataaaaa
      121 aattttatta tgtatttata aaatttttgt tacaaatttg gcataatata gtatacttta
      181 agtgtgtatt aggttaaatc tataacaaat tagacgtatg atatagactt agtgtttatt
      241 ggcatttaca agaaatttgt taatatcaac tatttgtagt ttgggcagtt ataattacta
      301 taggggggat gtccaataca aaacaatcaa ccaagaacta atattatatt ataaagagtt
      361 atagttttgt gtgtttatgt ttttaattaa atttaaagtg ggaaaaatat atttgttaga
      421 atggagaata gcgagatgag taataaaata gttagtaaga gacaattaac agatagtatt
      481 tatttaatgg aaatagaggc acctagagtt gcaaaatctt ctcaaccagg tcaatttata
      541 ataattaaaa atgatgaaaa gggagagagg attcctctta caatagctga ctatgataga
      601 gaaaaaggaa cagtaactat tgtattccaa acagttggtg cttcaactaa aaagttagca
      661 atgtttgaag aaaacgattt tgtaatggat tttgtagggc cattaggaca agcaagtgaa
      721 tttatacatg aagatataga agaattaaga aataaaaaga tattatttgt agctggtgga
      781 gttggttctg ctccagttta tccacaagtt aaatggttta aagagcatgg attagatgta
      841 gatgtaataa ttggtgcaag aactaaagaa ttaattatat tagaagatga tatgaaaaaa
      901 gtagctaaaa atgtatatgt atcaacagat gatggtacat atggatttaa tggaagagtt
      961 acagacctat taaaagattt agttgataat caaggtaaaa aatatgacca agcaatagta
     1021 attggaccaa tgataatgat gaaatttatg tgccaattaa ctaaagaact aaatatacct
     1081 actatagtaa gtttaaatac aataatgata gatggaacag gtatgtgtgg tggttgtaga
     1141 gttagtgttg gaaatgaaac taagtttgca tgtgtagatg gtcctgaatt tgatggtcat
     1201 ttagttgatt ttgatcaagc aatgagaaga cagtctatgt acaagactca agagggaaga
     1261 gctattctaa aacttgaaga aggcgatagt catcatcata gtaattgtgg atgtggaggt
     1321 aacaaataat ggatgctaaa aaagtaaaag taccagttag agaacaagaa cctgctgtga
     1381 gagcaacaaa ttttgatgaa gtatgcttag ggtataataa agaagaagct atggcagaag
     1441 ctaatagatg tttagcttgt aaaaaaccaa aatgtgtggg tggatgtcca gtaggaatcg
     1501 acataccagg gtttataaca aaaattaaag aagatgatat agaaggtgct gctaaagtaa
     1561 tagctaagag cagttcatta ccagctgttt gtggtagagt atgcccacaa gaaagtcaat
     1621 gtgaaggtgt atgtatactt ggaataaaat cagatgctgt atcaataggt aaattagaaa
     1681 gatttgtagc agattggtca aaagaaaatg acataaattt atctgataca gagcctaaga
     1741 aaaatcaaaa agtagcagta ataggaagtg gtccagcagg tctagcttgt gctggtgatt
     1801 tagctaaaaa aggctatgat gtaacaatct ttgaagcaat gcatgagcca ggtggagttt
     1861 taacttacgg aatacctgag tttagacttc caaaacaagc tgttgttcaa cctgaaatag
     1921 acaatataag aaaattaggt gtaaaaatag aaactaatgt aattgttggt aaaacaatta
     1981 cagtagatga acttatagaa gatgaaggat ttgaagctat attcataggt tcaggagctg
     2041 gtcttccaat gtttatgaat ataccagggg aaaatgcaaa tggagtgttt tctgcaaatg
     2101 agtttttaac tagagtaaac ttaatgaagg cttatagaga tgactatgat acacctatta
     2161 gttctggtaa aaaagttgct gtagtaggtg gtggaaatgt tgctatggac gctgctagaa
     2221 ctgcattaag attaggttca gaatcatata tagtttatag aagaagtgaa aaagagcttc
     2281 cagcaagagc tgaagaagtt catcatgcaa aagaagaagg cattatattt aatacattaa
     2341 caaatcctaa ggaaatttta gtagatgaaa atggatatgt taaaggtatg gtttgtataa
     2401 gaatggaatt aggagagcca gatgattctg gaagaagaag acctatagaa atagaaggtt
     2461 ctgaatttgt acttgatgta gacacagtta taatgtcact tggaacaagc ccaaatccac
     2521 taatatcttc tacaacaaag agtcttaata taaataagaa gagatgctta ataacagatg
     2581 aaaatggtca gacttctaaa gagggtgtat ttgcaggtgg agatgctgtt actggagcag
     2641 caacagtaat atctgcaatg ggtgctggta aaacagcagc agcatcaata gatgaatatt
     2701 taaaaacaaa agttaatgct taatttgtaa attaaagaga gggtgtctca aaatgaactt
     2761 tttagttcat gaggcacttt ttttgtacaa aatcaaatat gttttaatca tttcaacaat
     2821 gaaaatttca ttcctgtaga aagtctaact tttaagtctt agtacaatct ctattttgat
     2881 gtaggcactt ttttagatgg tttaataatt tatcagttat tattgtaata tttgatacta
     2941 agtaacataa ctttgtctaa ctatgataaa atagttatac aataaaggtc ttgtaaggag
     3001 tgaataatgt gtggctaata aaatcagatt tgtcaaatct aacattaaat aatagaaaaa
     3061 taaattgtgt aattaatggt attttaatat gaaaaaaaga gaaaaagtat ttgatgggct
     3121 agtttttaag catatattaa tcttattaat actattagtt ttgattgatt taacaagtac
     3181 catcatatat gcaagtaact ctatggaaat tacttctaga aatatgattg aggcatcaaa
     3241 aagagaactt gaaaactatt tagaagtaaa catatcttta ttaaaagctc ttagtcaaga
     3301 tgatagattt tctaatggtg aaacatcact aattgaaaag ggaaaattat taaggccata
     3361 tcaaaaggaa tataatcttt ttatgattgg tataacagat acaaaaggaa atgcttcaag
     3421 tacatatagg gaaaatgtta actcaataaa agataagcct agttttgaga aagcaattaa
     3481 aacaaagcaa gtagtagttt cagatattga agtcagtaat gtaacaggtg acaaagtatt
     3541 tatcatatat gtaccaattg taaaaaataa tgagatgatt gggaccattt ttgcttcttt
     3601 ttattttcaa gatgtaaata atttaataag tagaagcaat tttgatgatt ctattaaatt
     3661 tctaatgata gataaagatt atactattat ttctcatcca aacaaaaaat atgtaaatga
     3721 taaaagtaag atgcttgatt tagaagggaa tattatagga accactaaaa gtgaaatctt
     3781 aaaaaatata aataaaaaat gtcaaggtga ttttttatct tgggataatt ggagattata
     3841 taatgtaaaa tatacgaaca taaagtggac taattggact ttagtatcaa aatgtaatat
     3901 atttaagaac tttaaaaatc taatagttaa ttttatgata aagttgtatt tttatatagt
     3961 aatatttatg atattgtgga aattaagtaa tgctaaatta atagaacaac ttaaaaaatt
     4021 ggcttattat gattctttaa gtggaataaa aaataaagaa aagtttagaa aagattctat
     4081 gtatatttta aagaattatt atcaagataa tttttactta gtacaattgg atgtcaataa
     4141 atttaaatat ataaatgaga tgtttggata tgctgaaggg aataagatat taattcatat
     4201 atcacaggtt ttaaataata atacaaataa atatgaaatt tgtgctagga tggataatga
     4261 ccattttata ttgttgattg cttgtaatac tgaagatgaa cttttaaata gattatctaa
     4321 aataaataaa gaaatttgta acttaaatac tactaactca tctaagtata aaattgttat
     4381 gtcaagcgga atatataaga ttactaaaaa ggatgatatt aaaaagattg acctgttaat
     4441 tgatagagca aatattgcag caaaaagtaa aaaggaaaaa tatgaacatt catattcgtt
     4501 ttttaatgaa gatacaagaa atcgattgta caaggaaaaa cgattggaag ataatatgaa
     4561 taaagcttta gaaaaaggtg aatttatagt atattatcaa cctaagtata gtttagatga
     4621 tgtaaatgaa attgaaggag cagaagcctt gataagatgg aatagtccag aatttgggtt
     4681 tatttcacct atagattttg tacctttatt tgaaaagaat ggttttattg taaatattga
     4741 tatgttcgtg tttgaagaag tatgcaaaac attaaacaag tggataaata aagggtatac
     4801 tcctgtacca atctctgtaa atatgtctag agttcattta tatagggata attttataga
     4861 aaatataact gatttgataa gtaaatacaa tatatctcct gagtttattg aacttgaact
     4921 aacagaaagt gttgtgtttg ataatttaaa tatattgatt gatataatga aaaagattaa
     4981 agagatagga ttccttatat caatggatga ttttggttcg ggatattcat ctttaaatct
     5041 gttaaaagac ctttcttttg atattttaaa attagataga ggatttttaa tcgaaacaac
     5101 agatacaaaa cgtggaaaaa ttattatttc taagattgtg gaaatggcaa aagcgattga
     5161 tattaaagta atctgtgagg gcgtagaaac ttatgaacaa gtagagttct tgaaagagat
     5221 aggttgtgat aaggttcaag gatacttatt tgctaaacct atggtattag atgaatttga
     5281 aaaacactta aactttaaat ttgattaatc attaataatt attagactat aatataccct
     5341 aacaacttac ttacaaatat gtaagttaat tgttagggta tttttatggt taaagtagta
     5401 tattcacgat attatggtat tgtagtaaaa ataaaaaatt atggagaata taaaatgaac
     5461 atattgagta ttagaaatat atcaaaaaca tattgcggaa atattccatt taaagcatta
     5521 gataaggtta gtctaaatat agaaaaggga gaatttgtgt ctgttatggg accatctgga
     5581 agtggtaaat ctactctttt aaatataata tctacagttg atagacagag tgaaggtgag
     5641 gttgtattag atggatatga tgtaagtaaa ttgaaaggag aaaaacttgc tgaatttaga
     5701 aggaaacaac ttggttttgt atttcaggat tttaatttga ttgacacttt aactgttggc
     5761 gaaaatatta tgttgccact tacactagag ggggcaagta tcaaagatat gaatatacaa
     5821 actaaaagta tatctaaatt tttaggaata gataaaattt tagatagaaa aacctatgaa
     5881 atttcaggag gtcaagctca aaggtgtgct attgctagag ctattataaa taaacctacc
     5941 atacttcttg cagatgagcc aactggaaat cttgattcaa aatctactga tgatgttttg
     6001 aaattattta ctaggataaa caaagaacaa aatgtaacaa cacttatggt aactcatgaa
     6061 gtatatagtg caagttattc agatagagta atttttataa aagatggttg tatatataca
     6121 gaaataaaaa aatctgaaag cagtaattct ttctattctg atatactagc tgttttgtct
     6181 caaataggag gtgtaagata gtggatttta gaaagtttgc ttataataat atagttagaa
     6241 atttcagggc atatttagca tattttttaa gttctgtttt ttctataatg atattttttg
     6301 tttttgcagt gtctatgttc catccgatta taacaaaatc tggaatgcag agtggttcta
     6361 ctgcatttat ggctcttatg acttcagaat taacaatatt aggttttagt ctacttttta
     6421 tattgtactc tttaggaaat ttcttgaaat atagattgaa agattttgga gtattgatga
     6481 taattggaat gagcaacaga caactgaaaa aattgatatt aattgaaaat ttgataatag
     6541 gatttttagc agtgatgtta ggaatattac ttggtttatc aatttcaaaa ttgtttttat
     6601 tgtatttaag caaactgttt tatatgaatt taactgaaat ttattttcca gtaaaagcaa
     6661 tactattgac tattgtatca tttatgattt tatttttgat aacaggacca atgagcttaa
     6721 aattattgag aaaaaagagt attttagagc ttttagtagg tacaaaaaag cctaaaaaag
     6781 agataaaatc ttcaaggcta tttggaataa ttggtgtaat atgtcttata ttaggatatg
     6841 ctatgatact atttggcaat aagttaaaaa taaatggagg tatgtataca acagcactat
     6901 taattacttt ggggatattt ttattttttt ctcaatttac tattttgata ttaaagtatt
     6961 taaaaaataa agaaaaattt tataagaaca aagtaaatat gttacttata agtaatttga
     7021 tatataaatt aaaggataat acacgattgt tatttttaat aacaatactt ttatcggcta
     7081 ctttagtagc atttacaaca acttcaacac ttgtaagttc tcaaggagaa gcttctaaaa
     7141 ataatttccc aatggtttac tcatattttt cagagcataa taatgaaaaa gaatatgaag
     7201 aactacaaca aattagagaa gcaatcaaag gatatgatta taaggagtta agttttcctg
     7261 tacttaaata taatagggaa gtcttactaa gtgtaaagaa ttataacaaa ttatcaaagg
     7321 aattgggatt agataaaatt agttcaaagt tagaaaaata tgaagggatt ataattccta
     7381 gtagcaattc acaagaacat ataaattctt taaaacaatt aaaaaattat agtataaaaa
     7441 atttaaatat agaagtaaaa aaatcaaaaa ataaaataat ttttcctaca ggactgttta
     7501 gtaaagttgt agttataagt gatgacttat acgatgaagt aaaaggtgaa ttttcaaaaa
     7561 ttaattttca tggatttgat tataaaaact ggcaaagcag tgcaaagata actgaaaatt
     7621 taaaagaaaa acattttaat ttggatagag aatataacag gtcatatttt ttaacattac
     7681 cagatatgta tttagtagag ttacaacaaa gtaaaattct tcaatttatg ggtgttttta
     7741 taggagtgat attatttata gcagttttta gttttttata cttcagatta tatacagacg
     7801 agatagaaga taatgtaaag tacaaaaaac tatcaaaaat aggtctatct tttaaaaata
     7861 tgaataagat tgttagtata gagataggta cattgttttt tataccgtat tttatagcaa
     7921 ttataaatag cataatttct ttactgtttt taaatcaagt attaaataat agttttaggt
     7981 tagaaaattt gggtatatta ctactgatat catctatata ttcactttat ttttacttat
     8041 taaaaaaaat ttatactaga aaagtttggt tttttgatta aagtggtata taatagatat
     8101 ataaattaat atttaaaaag tagttaatat taggggaggg catttgcacc tcccttgtaa
     8161 tatgtggaaa attgaatatt agaagaagga ggagacttga tggaaaatca acaattatta
     8221 ggaacagaac gaattagtaa attactacta aaatattcta taccagctat aataggtatg
     8281 ttggtaaata gtttatataa tgtagtagat agaattttta ttggaaatat accaggggtt
     8341 ggaccacttg caataacagg tcttggtgta acaatgccaa taatgacaat aatacttgca
     8401 tttgggatgt tgataggtat aggaactact actaccatat caataaaact tgggcaaggt
     8461 aaagtagaag aggcaagaaa acttatagga aatgcaatga cgttatctgt aataacagga
     8521 attatcataa tgatacttgg aatattattt gcaaataaaa tacttacatt gtttggagca
     8581 agtgaaaata ctttaatata tgcaaaatca tatataaata ttatattatt aggtacagta
     8641 gtaaatcttc tttccttttc tttaaaccac tcaataagag ctgatggtag tcctaaaatt
     8701 tcagcaggaa taatgatagt aggatgttta actaatatag ttttagactg gatattaata
     8761 tttggattca atttgggaat acaaggagct gcaattgcta cagtaacttc tcaggctctt
     8821 acagctattt taactatagg gtattatata agtggaaaat caaacttacg attcagtaaa
     8881 tctaatctaa aattagataa aaagctaata aaagcagtgt ttgcaatagg tatgtcgcca
     8941 tttgcgatgc aacttgcagc aagtttagtt caagtaatat caaatattgc acttaaaact
     9001 catggtggag atttagctat aggggctatg gctactattt cttccattgc aatggtattt
     9061 ttgatgccta tctttggaat aaatcaagga gcgcaaccta ttataggttt caattatgga
     9121 gctgaaaaat atgatagggt taaaaaagca tatttaggtt cattagtagt agctactata
     9181 attttatgta tgggtatggt agtagttatg cttttcccag aagctattat aggtatattt
     9241 aataaagacc ctgaacttat gaatatatct gttaatggat taagaatata cttacttatg
     9301 ttgccaattg taggcttatc agttacagga acaaacttta tacaatctat aggaaaagca
     9361 aaaatggcta tgttattgag ccttttaaga caagtaattt tattgatacc agcagtatta
     9421 attcttccta cattcttagg tttacagggt gtatggacag ctcaaccagt gtctgatttt
     9481 atagctacag taattacagg tatagttgta tttagagaat taaaaagata tactcctaaa
     9541 actgaaaaat taaatgaaaa tgaaagacta aatgagataa ctactgagta aaaatataaa
     9601 ttcagataat tgagcaagaa attgcaaaaa atacgattat atgataaaat aaaaccgctg
     9661 tcaaggataa gagaaattct aattatggag tgattttatg gaatttacaa agaaaagcaa
     9721 attaaaaaat atgtatgtaa acatgaatgt agctagaatg ttgtctaaga taaatgagta
     9781 taagggtagg caactgcttt acaaaaaaca accaaaagaa attttagaaa acctagaaaa
     9841 aaaatcttta gtagattgtt ctgaatctac atacattgga aatcaaagag atagtagtaa
     9901 ttttaatcta gaaaagttga taagtaatga agttacacct agaagtagag aggaattgag
     9961 tattgttgaa tacagagatg tggtaaaaac tattaacagt gcttatgaga gtattcccat
    10021 cagttcacaa acgattcttg agcttcatgg gtacttatat aaattttcat ctactagagg
    10081 aggaagttat aagtcagata atgattttat tgaacacaat ttaaaaccta gcgaatttat
    10141 aagtattgat tcaagtgtca ataaagttga aaaagctgta gaagaaatat gtgaagctta
    10201 taatacattg atagaggaag atgaaattga tatattaata ttaatttctg catttgtgtt
    10261 agatttcata ttgatacatc cattcaaaga aggtaatata aaaatggcga gagtacttat
    10321 cctattgtta ctaaataaaa atgggtatga agttggaaga tatataagtt taggaaagat
    10381 atttgatgat agttcatatg aatattatag taatttaaat tatttgaaag cctcaatagg
    10441 tagtgaaaaa gcagatatga atgcatggat tgagtatttt ttagagacga tattaactgc
    10501 atatgagaag ctggatgata gtttaaatat atctgataag aaaagacaaa caaaaactag
    10561 tagaatagaa aaaataataa attctaccct tggatatttt acaaaagaag atataagaga
    10621 tttatgtcct gacattccag aacctactat aaatagagtt tttaataatc taagaaaaca
    10681 agataagata gaagttgttg caagaggaag aagtgcaaaa tggaagaaaa aatattaaaa
    10741 aatgtttaaa taactaaaat ggtatagtgt tttacactat accattttta atgtcattag
    10801 catgagcaat aatttaacaa cttaagcaat atcaatttta tttattgatt atttttgaac
    10861 tgaaaaatgg ggttatatgg tatactacaa taataattaa ttttggatga gaatatataa
    10921 cgttacagaa tatcttagga gtatatgtat aaaaaatata ataaaagtgt gaggtttagt
    10981 aattaacaaa ttatgtggct tcacactttt ttataaaata aaaatactta gcagaagaat
    11041 attttagttg atatgtttat aagatagtac ttgtttgggt aaaagtataa atagtaaaaa
    11101 agtagaagta atgtgtataa aaacataagt tacattctgt aataatagtt attttataat
    11161 tcaacaaaag aatagaatgg gtatatttgt gaaataataa tataaaataa tcttaggagt
    11221 gatcttatga agaaaaaatt attatatata aatgtaaatt caaaacctga agacttatct
    11281 tcaagtaaaa ctgtagcaag aaaatttata aataaattta tggaaaaaaa caaagatttt
    11341 gaggttgaag agatagacct ttataaagaa catataccga gacttgagta tcagtacttt
    11401 gaaaaaagaa atagcatagt tagtgaagaa aatgctaaaa atttagacga taaggataga
    11461 aaagagctta caaagattag aaatctttgt gaccaatttg tgagtgcaag tgtttatgta
    11521 atagcagcac ctatgtggag tttatctttt ccagcaccac ttaaagagta tatagattgt
    11581 ataattcaag atggaaaaac tatatctttt gaaggcaatg ataaaccaca aggaatttta
    11641 aatgatattg atagaagtat ggtatatata caatcttctg gtggacacat accatgggtc
    11701 ttgaagccag ttatgaataa agggttaaat tatgtggaaa gtattatgaa atttatagga
    11761 attaaaaaat ttgatgaatt gttagtagat ggaactggaa ctagtgaaga agaaagacaa
    11821 gctgcaatag aaaaagcatc tgaaaaaata catggtataa tagatggtat gaaattttaa
    11881 ttataatatt ttattaaaaa tataaaggaa aaacctcttt taatgtagaa acttatattg
    11941 aaggaggcga gaatcatgcg agaagaaaaa agtaatgaaa agtatgattg ttattggtgt
    12001 aatcaagaaa ataatttctg tgtagaaata aaagataata tagtaatgat agatgatggc
    12061 actggtacgt taaaacaagc cgttttcata gggtataaac aaatccaaat taatttaaat
    12121 tgttcacatt gtcaaaactt aaatagaata aaattaaatt tgtagaattt taaaatggaa
    12181 attattgaag gaattaaaaa tagaaagtgt taatatttag actgaaaatt atattttata
    12241 caataaaagt ttatttaaat aacattgtat tttaatattt attttcagtc ttactttatt
    12301 aaaattattt tttggttatg tctggaaaat atctgtctac taatttttct gaaatatttt
    12361 ttaattggtc agccattgaa gtcagactta ataaggctat caataaatca tctttatttt
    12421 ctggatttat actaatattt tcaaaattag actctataaa gtccggtata ttctttcttt
    12481 gattttcttt tattaacatg aatttttcgt aacatgaaac taaatctttt tcactgaaat
    12541 tatccttttc atacacacca tgtaagattc ttttaatttc ttgtattgta agtgtatttt
    12601 tcatagaata aataattatc atctgtaaaa tttgttcttt agtatacttt tttcccttaa
    12661 ctggtttgat taatccctct ttgctgtaat tatttatcat ggttttagta agaattttat
    12721 cactttcaaa tcttttatta ggagaaagtt tattgtcaat tagagaaata atttgatcca
    12781 tatataagtc aatagaggga atatcgtttg aagttatatc tgcattattt agtgtttcta
    12841 gtattatagt attaagttca ttattcatca tatgttacct ccataatata tataatacac
    12901 taaattagaa agtaaaacaa tattaagact tgtaaaaaaa acataaagtg gtataattaa
    12961 atatataata tagtaatgaa aactatattt atgaatctga tttttaaaat acataattgt
    13021 aggaggacga aatgtatcaa ttttttttaa agggtagaga cccaataagc agtttaactc
    13081 attttatagg tgcttgttta tctcttttag caactataat tttagttttt caatctgtta
    13141 cattacagga aacttctctc ttgatgatag tatctgtatc ggtatttgga ctttcactaa
    13201 ttgctttata tagtgcaagt tcgtattatc attttttaaa ggggacacca gaacaagaat
    13261 tgttttttag aaaagtagac catgcaatga tttatgtatt gattgctggc tcttatacac
    13321 caatatgtct gaattttatg gaaaaaaaag aaggcataat atttgttaca gcaatatgga
    13381 tagttgcatt tattggcata ataataaaaa tattttggat ggatgcacct agatggttat
    13441 ctaccagtat atatttactt atggggtggg caattgtttt tgatataaat gcattcaatt
    13501 caattcctaa ggattgcctt agactattaa ttatggaagg tgtatcttac tctataggtg
    13561 caattattta tataattaaa aagcctaata taagtcctga gtttggattt catgaaatat
    13621 ttcatatttt tattatgata ggttctttat ttcacttttt agcagtttta ttgtatgttt
    13681 tatagtttta aaagatttga ttaattgata ctaaaattct acaatgaata aaatggaact
    13741 gccttatata gattatatct tcgacaataa gacagttcct tattataaat attaaattct
    13801 acttataata aaattttgat aaaaatagtc cattcaaaat gcctattcca taattccttt
    13861 aatgtacttt tcatttacga catatagttt gaatttatgt actataatta tatcctctaa
    13921 attctctgaa acactaacaa ttctgacaca tttgtttcta atttctacag gtaaatctaa
    13981 atcatttgtt aaattcacat agtcatcata tttatacata aaatcatccc tttacattaa
    14041 gatatactta ttatactata ttttaataag tttttttaaa ttattacaat ttttcccgaa
    14101 atttcatttt ttataca
//
LOCUS       DAMJWO010000096        13392 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.099, whole genome shotgun sequence.
ACCESSION   DAMJWO010000096 DAMJWO010000000
VERSION     DAMJWO010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13392
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.099"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            125..1312
                     /locus_tag="PC366_003170"
     CDS             125..1312
                     /locus_tag="PC366_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HDF2578662.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGINAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYNGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIRTIGFGPSKENLAHTIDEYIELDQLFKGAEGYYGILKSV
                     YKK"
     gene            1328..2911
                     /locus_tag="PC366_003171"
     CDS             1328..2911
                     /locus_tag="PC366_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HDF2578663.1"
                     /translation="MRTLIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDYNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDTIGKSLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIKDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            2939..4267
                     /gene="ssnA"
                     /locus_tag="PC366_003172"
     CDS             2939..4267
                     /gene="ssnA"
                     /locus_tag="PC366_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HDF2578664.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTEEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEMAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISAEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIINGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            4466..5818
                     /locus_tag="PC366_003173"
     CDS             4466..5818
                     /locus_tag="PC366_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HDF2578665.1"
                     /translation="MSQDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLKFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVLLNIFFNELGSKKEKNNKVEEAK
                     "
     gene            6010..7119
                     /locus_tag="PC366_003174"
     CDS             6010..7119
                     /locus_tag="PC366_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2578666.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKETGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMAARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            7402..8793
                     /gene="hydA"
                     /locus_tag="PC366_003175"
     CDS             7402..8793
                     /gene="hydA"
                     /locus_tag="PC366_003175"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HDF2578667.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGVTKTADNFETGTKAAIVGGTTTILDFATQAKGCSLK
                     DGLEEWHEKAKDKSYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKSENNLSPKYHQLTRPAIMEAE
                     ATSRLMKIAEVANSKVYVVHLSCKESLEEVLKAKQRGVDVIVETCPQYLLLNDELYDL
                     DGFESAKYVMSPPLRNKENNEILWNAILDNQIDTIGTDHCSFNYKGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNAAKLFGMYPNKGTIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            8787..11348
                     /gene="xdh"
                     /locus_tag="PC366_003176"
     CDS             8787..11348
                     /gene="xdh"
                     /locus_tag="PC366_003176"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HDF2578668.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLAGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTADALREDAPKIHETGNILVKEHLVRGNAKEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEDDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAMAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     MTQVVCETASLLPENIVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASNKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVILDENGKLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVNSVPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            11500..12846
                     /gene="rpoN"
                     /locus_tag="PC366_003177"
     CDS             11500..12846
                     /gene="rpoN"
                     /locus_tag="PC366_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HDF2578669.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
BASE COUNT         5368 a         1547 c         2709 g         3768 t
ORIGIN      
        1 atttaataaa taaaatataa agaaataaaa aatcaataga ttaagtgaaa tgctaataaa
       61 ttaaaaaagt gaaatatcaa aataaaacgt caacaaatta aaaattatat gggggaatat
      121 caaaatgtta aatgaaacaa gaaaaaaaca attaactgaa gtatgccaag acttaataag
      181 aaatgctagt tattcaggtc aagaagaaaa cgtagtaaaa gctatagaag aaaattttgc
      241 tttactaggt tttgatagtt ggtcaagaga tagatatgga aatatagtag gatgtataaa
      301 aggaaataaa ccaggtaaaa aaatattatt tgacgggcat atagatacag ttccagttcc
      361 agatgcaagt aaatggagtg ttcctccttt tgaagcgaga atagtagatg ggaaaatata
      421 tggtagagga acttctgata tgaaggggca agtaagtgct atgatggctg ctgtttcata
      481 ctttgcagaa gatactaaca aagactttga aggtgaattg tatgtagcag gtgttgttca
      541 tgaagaaata tttgaaggtg tttcagctag agagataagt aaggctgttc aacctgatta
      601 tgttgtaata ggtgaatctt cagaattaaa cttaaagata ggtcaaagag gtagaggaga
      661 aatagtagta gaaacttttg gtaaaccagc tcactctgct aatccagaaa aaggtataaa
      721 tgcagtttat aaaatggcta atgtaatcca aaagatacaa caattagtac ctccaactca
      781 tccagtttta ggtgatggaa tattagtttt aacagatata aaatcttctc catatccagg
      841 agcatcagta gtgccagatt attgcaaagc tacttttgat agaagattat tagttggaga
      901 aacaagagaa ggcgtattag ctccaataca agctttatta gatgaaatga tgaaagaaga
      961 cccagaatta aatgcaaaag tttcttatgc agttgaaaaa gctgattgct atacaggaaa
     1021 tactatagaa agtgaaagat tcttcccagg ttggttatat gatgaagaag atgaatttgt
     1081 tcaagcagcg tataatggat taaaagaagc tggaatagat tcagaaataa ctcaatactc
     1141 attctgtacg aatggaagtc actacgcagg tgaggctgga ataagaacta taggatttgg
     1201 tccttctaag gaaaatcttg ctcatacaat agatgagtat atagaattag accaattatt
     1261 caaaggtgca gaaggatatt atggtatatt aaaatcagtt tataaaaaat aattaggaga
     1321 tggttttgtg agaactttaa taaaacatgg gcttatagta gatggaaata aaacaccagc
     1381 atatgaagga gatattttaa tagaaaacga gaaaatatta aaaatatcac aagatttaaa
     1441 cgaagaagct gacaaagtta tagatgcaaa aggtagagtt atatgtccag gtttcataga
     1501 tactcatagc cattcagacc tagttatttt agttaatcca tataatgagg taaagattag
     1561 acagggaatt acaacagaag tgttgggcca agatggtata tctatggccc ctctacctca
     1621 agagcatata tcttcttgga gaaaaaattt agcaggtcta gatggtgaaa gtgatgaaat
     1681 tgattggaaa tatgaaacaa cagagaatta tttaaaaatg atggattaca atggggtagg
     1741 tttaaatgaa acttatttag tacctcatgg aaacgttaga atggaagcta tgggacttga
     1801 agatagacct gctactaaag aagaaattca aaaaatgtgt gaaatcacag agagagaatt
     1861 aaaagcagga gctataggat tgtctactgg acttatatat ataccttgtg catactcatt
     1921 gactgaagaa attatagaga tgtgtaaggt agtagcaaaa tatgacggag tatttgtagt
     1981 tcaccaaaga agtgaagcag atacaatttt aacttcaatg gaagaaatca tagaaattgg
     2041 aaaacaatca ggagtaaaag ttcatttttc acattttaag gtttgtggta aagcaaactg
     2101 gaagtatata ccacaagtta tagagctttt agaaaaagca gaaaaggaag gaataagagt
     2161 atcttttgac caatatccat atgcagcagg aagtacaatg cttggagtag ttttacctcc
     2221 ttgggcacat tctggaggaa ctgataagtt aatagaaaga ttaagcgatg aaaacgaaag
     2281 agcaaaaatg aaaaaagata tagcaaatgg aatagaaggc tgggataatt ttatagaatt
     2341 tgctggaata gaccaaatat ttgtaacaag cgtaaaaaca gaaaagaata aagatacaat
     2401 tggtaagagc ttattagaaa ttggaaaaat gagaggaaaa gacccattag atgcaacgtt
     2461 tgatttatta aaagaagaag aaaatgcagt tgggatggta gatttctatg gattagaaga
     2521 acatataata ggattcatga aaagagacga gcaaaatgtg tgtacagatg gtcttttagc
     2581 aggtaaacca catccaagag cttatggttc tttccctaaa atactaggaa gatatgttag
     2641 agagttgaat gtactaacaa ttgaagaagc tgtttataaa atgactaaaa aggcagctac
     2701 aagctttagt ataaaagata gaggcgaatt aaaagaagga tattttgcag atatagttat
     2761 atttgacaag gatacagtta gtggttgtga tgattttatc aactctatgc agtaccctac
     2821 aggtatagat tacgtaatta taaatggaaa ttgtgttgtt gaagaaggaa aatacaataa
     2881 aattaaagca ggaaaagtac ttaaaaatta aatcttagct ttaaggagga ataaatttat
     2941 gattttagtg gggaatggga ggctaataag ccaagattct ttaaatccct atatggaaga
     3001 tggatgtgta gtaataaatg ataatctaat tgaagatata ggtactacag aagaaatgaa
     3061 agctaaatat ccagtacatg aatttataga tgcaggcaag aaaataatca tgccgggtct
     3121 aataaattca catatgcata tatacagctc atttgctaga ggaatggcag ttccaggaaa
     3181 accttctgag aactttttag agatactaaa taatttatgg tggagacttg acaaacagct
     3241 tacactggaa gatacaaaat acagtgcata tgcaacgtat atagaatgca taaaaaatgg
     3301 tgtaacaaca gtttatgacc atcatgcaag tccaaatgca attgaaggca gtttgtttac
     3361 aatatcagat gttgcaaagg atttgggaat tagaacgtgt ctttgttatg aagtgtctga
     3421 tagagatggt ggaaatacaa tccaacaagg tatcaatgaa aacgtaaact ttataaaata
     3481 cgctcaaaaa gatgatacag acatgataaa aggaatgttt gggcttcatg ctgcatttac
     3541 actatctgat gatacattaa ataaatgtgc ttcagagatg gctggtcttg atacaggtta
     3601 ccatgtacat gttgctgaag gactagcaga cttacaatat aatgtagata aatatggaaa
     3661 aagggtttta gaaagattca atgattttgg agtactaaaa gaaaaaacaa tagcagttca
     3721 ttgtatatat ataagtgcag aagaaatcag tcttttaaat aaaacaaata catttgtagt
     3781 tcataatcca gaatctaata tgggaaatgc agttggatgt tctcctgcaa tagagttatt
     3841 aaaaagggga gttacagtag gattaggaac tgatggatat actagcgata tgtttgaatc
     3901 attaaaagtt gccaatataa ttcacaaaca tcacttaaaa gacccaagag ttggatttga
     3961 agaatcacaa acaatgttat ttgataacaa tagaaaaata gctaaagctt attataaaaa
     4021 tgacctagga gtacttaaaa aaggtgctta tgcagatgtt atagtagttg attatatacc
     4081 acatactcca ttgacagaaa atacaatagg gggacacact atttttggaa tgagtggaag
     4141 aagcgtagat acaactatta taaatggaaa agtacttatg aaagatagaa agttaataaa
     4201 catagatgaa gaaagtattc tagcaaaaag tagagaatta agtcaaaatc tatggaatag
     4261 aatttaaata attgattatg caaaattcta tgaagcagga accctgtgac tttagtcatg
     4321 ggaggttcag attaatatac aagtaagaaa caagaattta gatgttaaaa acagagctta
     4381 aacaaaaata ggaatttaaa tgaagtatat aaataaaaaa tatacggaat agaatattaa
     4441 attaaatata gaagggagac ccaaaatgtc tcaagataaa agccctaaaa tagctccagt
     4501 agatgaaagg ttacctgtat ccaaatcttg ggtattttca ctacagcacg ttttagcaat
     4561 gtgtgcagga gcagtagcag ttcctatgat gataggaagt gctgcacgac tagatcatgc
     4621 tagtattgtt tttttaataa atgcttgctt gtttatggca ggtataggaa cactcataca
     4681 aagtgttggt ataggaaata ttgtaggtgc taaaatacca gtaatagaag gaactagttt
     4741 tgccgctgtg gcaggtatga cagcaatagc ctcatcatat agtgattcac aagttgcaat
     4801 acagacagta tttggctctg taatagtagc tggattgttt tgtatattac ttgctccagt
     4861 atttgaaaaa ttaataagat ttttccctag tgtagttact ggaacagttg ttatggtaat
     4921 aggtatttca ctatttccag ttgggataaa atggataact gacaacaaat tggaagcggt
     4981 tgaaccaaac tcattagcat tagctttagc agtattggca ataactttac tttcatttaa
     5041 attcttaaaa ggaatttgga atagcacagc tatattggta ggtatagtac ttggtacact
     5101 actttccatg gcagttggaa tggcagattt tagtgcagta aatggagttg gttggcttaa
     5161 cttaaatgta cctttaaaat ttggaatgcc tagatttgaa ccatctgcaa tactatcatt
     5221 gtgtttgatt atgttggtac ttatgacgga atcagttggt aatatgatag ctattcatga
     5281 aatggtagac aaagaagtaa caggtaaaaa tattaaaaga ggtctatttg gagatggaat
     5341 atctacagca ttatctggaa tattcaattc atttccaata actccatttg gtcaaaatac
     5401 aggaatagta ggtcttacag gtataaaatc aagatttata gcagtttacg caggggttat
     5461 attgctagta cttggattct taccaaaatt tgcagcaata ataggagcaa tacctaagcc
     5521 tgttctcgga ggcgtaggat ttgcaatgtt tggaatggta atggttggag gagtaaaaac
     5581 tttaagcaaa gtgaaatttg atggaactaa aaatggggtt atagtagcag ttagtgttgg
     5641 tttgtctatg ataccactaa caaatcccga tttctatcat aatttcccaa cttgggtaca
     5701 aacaatattc catagtggaa taacaacagg tagtttatca gcagtgcttt taaacatatt
     5761 cttcaatgaa ctaggttcta aaaaagaaaa aaataataaa gttgaagaag caaaataaaa
     5821 ataaaacaag taaaaatcta tattgactta aagtcattaa gcattaataa aaataattca
     5881 gagatattaa taattcaaca aaactatctt atattttaaa taatataaaa aagtaaataa
     5941 ataacgaata caaataaaag aatacaatct aaatattaaa aatatttaat ttaagggaga
     6001 gataataata tggctaattt aaaagttaat ttatatggaa tggaattttt aaacccaatt
     6061 atgacagcgg caggacctgg agcaaaagat ggtgctctct gtcaagaggc agcaaaaggt
     6121 ggagcaggag ctatatgtac aaaaactata tctgtattac cagctgatgt accaagacca
     6181 tgtatggcaa aaactaatag tggtttttta aacacagaat tatggtcaga gcttccaaaa
     6241 gagcaatgga tagaggaaga atacaaaaag gtaaaagaaa cagggcttcc agtaatagta
     6301 agtatgggat attcagcaga gcaaatagct gaggttgctc ctttagtaaa gccttatgca
     6361 gatgcagttg aattatctac tcattatgta ggtacagacg ttgcaccaat agtaaatgct
     6421 ttaaaagctg caaaagctgt tttagatgta ccagtattta tgaaaatgag tcctcatact
     6481 gacattcaaa ctattgcaaa agctgttgaa gaagcaggtg cagatggact tgtaatgata
     6541 aactcatttg gaccatgtat ggcaatagat gtaaatacag gataccctat aatgggaagt
     6601 aaagctggat acggatggtt atcaggtgca ccaataagac ctctagcaat aagatgtata
     6661 tatgaagctt ctcaagttgt aaatatacca ataatcggtg ttggtggaat cacttgtgga
     6721 aaagacgtgg ctgaaatgat gatggctgga gcaagtgctg ttcaagtatg tacagaagca
     6781 atccttaaag ggccttctat ctatggaaaa attgctaaag aattaaatga atttttagat
     6841 gagaatggat atgctgatgt taatgaaata aaaggattaa ctcataagaa aatggcagct
     6901 agagggttta gaactcattc agtagctcca gtagtggatg ataacaagtg catcaaatgt
     6961 aagcaatgtg taacaagctg tgtatacgaa gctttagaag ttacagataa gttgaacata
     7021 gatgcagaca agtgttttgg atgtggatta tgtgtaacta gatgtccaaa aggagcttta
     7081 agcatctgct acaatcaagt agaagctatg aatgagtaat aattatatag aattttggta
     7141 attaacttag agtaataggt attaggataa taaaatatat cagataaaca aacacacatt
     7201 atgcattaat aatacagtct aaagttaata attttattat attgatttaa ctaaatatta
     7261 gtttagctga atattaattt aattaggtat tggtttaatc ttaatataga tttactacgt
     7321 ataagtgaac taactagatt actttaagtt aattttttca tataaaataa attgatacat
     7381 tacaagtaag gtggagtcta tatgggaatt gttttaaaag gtgggaaagt agtaacaagt
     7441 gaaaaaactt actgtgcaga tgtaagaata gaagatgaaa aaatagtcga tataggtctt
     7501 gatatatcaa aagaaaatga tgaaatagtt gatgttagtg attcttatgt tataccagga
     7561 ggtatagata cacacacaca ctttgactta gatacaggcg ttactaagac agcagataac
     7621 tttgagacag gaacaaaagc tgctatagta ggaggaacta ctactatatt ggattttgct
     7681 acacaagcta aaggatgttc tttgaaagac ggattagaag aatggcatga aaaagctaag
     7741 gataaatcct attcagatta tggctttcat atggctataa cagattggaa tgactcggtt
     7801 tgtaatgaaa tggaggatat ggtgaaagag ggagtatctt catttaaact gtatatggcg
     7861 tataaaggaa gccttcaagt tgatgatggt gtaatctttg aagcattgag aaaagcagaa
     7921 gagataggag ggattattgg tttccattgt gaaaatgggg acataatatg tgaacttgtg
     7981 gataaagcaa agtcagaaaa taatttatct ccaaaatatc atcaattaac tagaccagct
     8041 ataatggagg cagaagctac atcaagactt atgaagatag ctgaagttgc aaactcaaaa
     8101 gtatatgtag ttcacttaag ctgtaaagaa tccttagagg aggttttaaa agctaagcaa
     8161 agaggtgtgg atgtaatagt tgaaacttgt cctcaatacc ttctattaaa tgatgaatta
     8221 tatgatttag atggatttga aagtgctaag tatgtaatgt caccaccttt aagaaataaa
     8281 gaaaataatg aaatattatg gaatgctatt ttagataatc aaatagacac tataggaaca
     8341 gaccattgtt cttttaatta taagggacag aaggaacttg ggataaacga tttcagtaag
     8401 ataccaaatg gttctccagg tgtagaacat aggatgagtc ttttatacac atatggagtc
     8461 tgtaaaaata aaatatctat caacaagatg gtagaagtaa catcaactaa tgcagcaaag
     8521 ttgtttggaa tgtatcctaa taaaggaact atagaaatag gcagtgatgc agatatatta
     8581 gtcttaaatc caaacaaaaa atccaaaata gaagcaaaaa aacaattaca aaatgtagat
     8641 tatacacctt atgaagggta tgaagtggat tgtcaaatag aacatgttta tttaagagga
     8701 aaagaagtag ttagagatgg agaattaatt tgtaatactc caagtgggag atatataaat
     8761 aggcgtctaa caaagggggc tagagaatgg tagaatttat attaaatgga gagaaagttg
     8821 ttgcaaaaga aggcaaaaaa cttttagact tccttagaga agatatgaat ataacttcag
     8881 ttaaaaatgg ctgttcagaa ggtgcttgtg gaacatgtat ggttataata gatggtaaag
     8941 ctactaaagc atgtgtattt aaaactgata aattagctgg gaaaaacata acaactatag
     9001 agggattatc agagagagaa agagatgttt ttgcatattc ttttgctagt caaggagctg
     9061 tacaatgtgg attttgtatt ccaggtatgg taattagttc aaaagcactt atagatgtta
     9121 ataataatcc tactgaagat gatataaaga aagctttaaa aggtaatata tgtagatgta
     9181 cagggtatgt aaaaataatt aaagctgtcg atttagcagc aaagattttt agagaaaata
     9241 tagatgtgcc aaaagtaaac tgtaagggtc tagtaggtga aaatcttcct agagttgatg
     9301 cagttggcaa agcacttgga tattctgaat atgtagatga tatgagaatt gagggtatga
     9361 tttatggttc agcagttaga gctaagtatc ctagagcttt agttaaaaaa atagatatag
     9421 aagaagcaaa agcttatcca ggagttgttg cagttctaac agctaaagat attccaggaa
     9481 ctataaaggt agggcactta aagaaggatt gggatacttt aataccagaa ggtgaaataa
     9541 ctagatattt aggagatgga atagttttag tagcagcaga aactagagaa gcgttagaag
     9601 aggccaaaaa gctagttaag atagattatg aggaattaac accattaagt actacagcag
     9661 atgcacttag agaagatgct ccaaagatac atgagacagg gaatatactt gttaaggaac
     9721 atttagtaag aggaaacgct aaagaaaaga tagaaaattc aaaatatgtt gtaactaaaa
     9781 gatatactac acctgctaca gaacacgcat ttttagagcc tgaatgtgca gtagctggtc
     9841 cttatgaaga tgatggagta ataatctatt caacagacca aggggtgttt gccactcaac
     9901 atgaatgtgc agatatgtta gggttaccat atgagaaggt aagagttata aacaaaatgg
     9961 taggaggagg gtttggtgga aaagaagaca tgagtgttca acaccatgca gccttacttg
    10021 cataccatac aaagagattt gtaaaagtac agttaacaag aaaagaaagt attattgttc
    10081 atccaaaacg acatgccaca gaaatggaat ttacgacagc atgtgatgaa aatggatact
    10141 taacgggtat gaaggcaacg ataatatctg acacaggtgc atatgcctct cttggaggac
    10201 cagtgctaca aagactgtgt actcatgcag caggaccata caattatcaa gatattgata
    10261 taacaggaac agcagtatat actaataacc ctcctggagg agcatttaga ggatttggag
    10321 ttacacagag ttgttttgca actgaatgta atctaaattt acttgctgaa atggttggaa
    10381 tatctccttg ggagataaga tataaaaatg caataagacc tgggcaagtt ttaccaaatg
    10441 gtcaatttgc agatgaagga acagcaatgg cagagacact agaagctgta aaagaagagt
    10501 atgaaaagca tccacgtgca ggtatagctt gtgctatgaa aaatagtggg gttggagttg
    10561 gtatacctga tgttggaaga tgtagattgg tgataaaaga tggcaaagtt cacataagaa
    10621 caagtgcttc ttgtataggt caagggcttg gtactgttat gactcaagta gtttgtgaaa
    10681 ctgctagcct acttcctgaa aatatagtgc atgaagttcc agatactcat ttaacaccag
    10741 actctggtaa tactacggct tcaagacaga cagtatttac gggagaagct actaaggttg
    10801 catcaaataa gttaaaagaa gctttagact ctggcaaaac tttacttgat ttagagggag
    10861 aagagtttta tggagaatat gaaagtatta cagataaaat gggttgtgac aaagaaaatc
    10921 cagtaagtca tgttgcttat ggatatgcaa cacaagttgt aattctggat gaaaatggaa
    10981 aactagaaaa agtagtagca gcacatgatg ttggaagagc tataaatcca atcagtttag
    11041 aaggtcaaat agaaggtgga gtagttatgg gtcttggata tgctctaacc gaagattacc
    11101 cagtagttaa ctctgttcct acagctaagt ttggtacatt aggtttattt aaatctacag
    11161 atataccaga aatacaagct ttaatagttg aaaagaacaa agatttattg gcttatgggg
    11221 caaaaggtgt aggagaaatt tgtacagttc ctactgcacc agcagtacaa aatgcctatt
    11281 atgtatttga taaagaattt agaactgagc taccactaca aaatactcca tatagtaaaa
    11341 aaaagtaaca aaaaaaagaa atattaaata aaaaaataga tgaaattgta aataaaaaaa
    11401 acccttttgc ataaggtata ttttaaatga tagaatatac atatacagga gggtttttct
    11461 tttataaaat aagtttaata aaattgagag gtgagcagaa tgaattttaa taatagtcta
    11521 gaattaactc agtctcagaa gctaataatg actacacaac ttaagcaatc attatcaata
    11581 ttaaatatga gtaagttaga gttagaagaa gagataaaaa gagaagcaga gaataaccca
    11641 ttagttgaag tcgagaaaag tggggagata aattgggaag agtatataaa agacatggat
    11701 aggtcaagac gtttagatag aacagagata agctataatc ctgataatga agttaatcta
    11761 gaaaatttag ttaaatattc gtcaaattta tatgaagatt taaaatttca gataagcctg
    11821 tataaactta cagacaaaga attggaagtc tgtgagtata taattgatag tttagatgag
    11881 gatggatatt taagaactga ggaaaaagta attgttgata ccttaaagat agatgaagaa
    11941 ctttttgaaa aatgtttaat tagtgttcag cagttggaac ctagtggagt aggggcaaga
    12001 agtctttcag aatgtctgat gatacaaatg gctagtttag gaatatataa tgaaatttta
    12061 gaggaaatcg ttacaaaaga cttaaattta attgcaaata ataaatataa agagataagt
    12121 aaaaagtaca atatgtcatt acaaaaatgt gttgaactaa taaacataat taagacatta
    12181 gaccccaaac caggaagaac ttgttcagta gagaaaagtg tatacattca acctgatgta
    12241 acagtagaaa agattgatga tgaatttatt gtatatttaa atgagaaaga ttcttaccaa
    12301 ataagaatca atagttatta taaagacata ttaaaaaatt cacagtctga tgaaagtgca
    12361 aaagaattta taaaagaaag actaaattca gcaacaggac ttatgaaaaa tatagagagt
    12421 aggaaaacta cagtacttaa gattgcagaa gagatagtaa aagctcaaga tgaatttttg
    12481 agaaaaggga caaaatatat aaaacctttg aaaatgaaag acatagcaga aaaattagaa
    12541 tttcatgaat ctactataag tagaggtgta aatggtaaat atatgctaac accttttggc
    12601 gtatatgaat ttaggtactt tttcagtagc gccattgaga ctgagaataa tgaaatggca
    12661 tctagtacaa gcataaaaaa aattataaag gaaacaataa aagacgaaaa taaaaagaaa
    12721 cctttaagtg atgaccatat atctaagtta ttaaaagaaa aaggaatcaa tgttgcaaga
    12781 aggacagttg ccaaatatcg tgaagaatta ggaatcccat cttcaagtaa gagaaaagaa
    12841 tactaataag taaaagacaa atatcagtat ggtaagggga aaaggctaat taagagatga
    12901 atgtagattg ggctaaaaat tttataaagt aaaataatag aatatggaaa agtattaaaa
    12961 tgctataagg tattaaaaaa ctggggaaca ttaaaacatt aagatagcaa agaacataaa
    13021 aaactaaaga agattaaaac attaaagaac attaggcttt gaggaatatt agaactttaa
    13081 agaatattaa aatttataaa atataaaaat actaaaaaga attgaaaaac tggggaacat
    13141 taaaatattg taaaatgcta aaaaactaga aaacataatt aaataagtgc ttataaagaa
    13201 tgattaaatt aaataagtgt ttgtaaagaa taattagata ttagaaaaag aagaatacct
    13261 agataaataa actattatta aatttaataa tcacaaaagg aaaacacgta gggtataaat
    13321 aaaaatctta actagataaa agtaaactta gttgtagata aaaataacta gaaataaaag
    13381 taactagaaa ta
//
LOCUS       DAMJWO010000097        12969 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.100, whole genome shotgun sequence.
ACCESSION   DAMJWO010000097 DAMJWO010000000
VERSION     DAMJWO010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12969
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.100"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            179..2038
                     /locus_tag="PC366_003178"
     CDS             179..2038
                     /locus_tag="PC366_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2578670.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVC
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICINKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVVRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEEILDKEFVYNS"
     gene            complement(2330..2929)
                     /locus_tag="PC366_003179"
     CDS             complement(2330..2929)
                     /locus_tag="PC366_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2578671.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(3032..3829)
                     /locus_tag="PC366_003180"
     CDS             complement(3032..3829)
                     /locus_tag="PC366_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDF2578672.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(3942..4047)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(4139..5125)
                     /locus_tag="PC366_003181"
     CDS             complement(4139..5125)
                     /locus_tag="PC366_003181"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDF2578673.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLNEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     gene            5609..7339
                     /locus_tag="PC366_003182"
     CDS             5609..7339
                     /locus_tag="PC366_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HDF2578674.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
     gene            7449..7529
                     /locus_tag="PC366_003183"
     tRNA            7449..7529
                     /locus_tag="PC366_003183"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7483..7485,aa:Leu,seq:tag)
     regulatory      8426..8530
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            8740..11214
                     /gene="gcvPA"
                     /locus_tag="PC366_003184"
     CDS             8740..11214
                     /gene="gcvPA"
                     /locus_tag="PC366_003184"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HDF2578675.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRK
                     SAGIFDVSHMGEVQIKGAESEKFIQNLVTNDISTLKINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSTKVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSK
                     EKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATAAIEACIMAMNQTRKSKIVVSKTIHHETLSVLRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYMATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            11214..12671
                     /gene="gcvPB"
                     /locus_tag="PC366_003185"
     CDS             11214..12671
                     /gene="gcvPB"
                     /locus_tag="PC366_003185"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HDF2578676.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIEDMIDQDMARQSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVPFLPIPLIERKEDKYVLNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
BASE COUNT         4870 a         1539 c         2142 g         4418 t
ORIGIN      
        1 tatattagaa aaaaattttt gtatatataa aggactctaa agatgaacta tataaaacaa
       61 ggtttatata ttctaatagt atagaaaatt ttattgtaaa cgcatgtata ttattagaaa
      121 aaatagtttg aaggtattca ataaacataa aaaacaatat aggggataaa ggtgttttat
      181 gaagagattt ttgaggagaa ttatcttagt tttatttatt ttgttgattt ttataagttt
      241 tatttctatt aaattaattc ataatgttgg agattatgga aaattgatta attatgttgg
      301 gattgtttgt ggagctagcc aacgtctaac taaactagag atgaatcatc aaccaaatga
      361 tgaattaata gaatatattg atgaaatcct acaggagttg attacagggc atggagatta
      421 tggtttagta atcactgatt gtaatgaata caatgaggac ttacttttat tagaaaaaaa
      481 gtgggaagat ttaaatattg aaattaaaaa agtaagaatg aaagaacaga ataaccagtt
      541 attaagtata agtgaagagt ttttttctct tgcaaatgat acagtgttta aaatagaaaa
      601 cttttctaaa gaaaaaagta attacttaat gactttaata ataattatat ctattatagg
      661 tatattagca tgtatcatat tgattttaca atatagtaaa aaaatggtta gactggaaaa
      721 attaaatgta gatttaaaaa atattgcata taaagatgaa ctaacaggag taaatactat
      781 agaaaaattt aaattggatg caaatcaaaa tatttgtata aataaggata agaaatttgc
      841 tgtattctat attgattttg aaaactttaa atacattaat gatatatttg gatatgatta
      901 tggtgacatg atactgaaaa gatatgctaa tcttatgatg aatgacatag ggaaatatga
      961 aatatttgca agagaaattg cagatagatt tgttgcgtta agatgctatg tagataagga
     1021 agatttagta gtaagacaac gagatgtaga caatgaacta attaatataa caaatgaaat
     1081 taaaaataaa catagtatta ctgttgtcag tggaatttgt tgcattgaag atgtaaatga
     1141 aaaattaagt atagatggtt taataaatag agcaaatttt gcacaaaaaa ctgttaagaa
     1201 taaaccaggt actaattatg ctttttataa tgacagtatt cgtaaaaaaa tgattgaaga
     1261 aaatactatc aagagtagaa tacatgaagc tattgaaaaa agagaattta tagtttattt
     1321 acagcctaaa gttaatttac atagtcaaaa aataaattgt gcagaagctt tagttcgttg
     1381 gcttactccg gataaaggta ttatatctcc agcaatattt attccagtac ttgagaagaa
     1441 tttttttatt gccttagtag ataagtatgt ttttgaggag gtttgtaaat ggattagaaa
     1501 gaggttagat gaaaataaac cttttgttca gatatcagtt aatgtttcaa gaatacaatt
     1561 ttataacact aaatttgtag aaacttattc caatatacaa aataaataca ggatacctaa
     1621 aaatactata gaaattgaat ttacagagag tgttgctttt gagaatcaaa aacatctttt
     1681 ggaaattata catgatttgc atgaaaatgg atttacttgt tctttagatg attttggaaa
     1741 aggttattcg tctttaagtg ttttaaaaga tttaccattt gatgttttaa agcttgactc
     1801 tatgtttttc aaggctagtt tagataaaga taaagagaaa atagtaataa aaaatattgt
     1861 acatatgtta aaagagctta atatcacaac tgttgctgag ggcattgaat gcaaggaaca
     1921 agttgaattt cttagggata ttgggtgtga tttagttcag ggatttgtat tttataaacc
     1981 aatgccaata ttagaatttg aagaaatatt ggataaagag tttgtttata atagctaaaa
     2041 tgtactttat aaaatatgaa ctaattaagt aaaattattt tgtactgaat aaatttttac
     2101 tttatttaca gaatagtgat tatttacaga aaagggcgaa aagtgtattc ctttaagtat
     2161 gggatggata gcacaaatag gggagaaaaa atattggcca tataagaatg cataataata
     2221 taaatatttg aaaggtcagc attatataaa aattaaaaag aaaataaata atttttctat
     2281 aaaaaagaga ctatgagaaa agttactcat agtctcctaa ataatgtatt tattttcttc
     2341 ctgcaaccca ttttaagccc caatgaaatt cagtatccat ttctctatga cctttgaagt
     2401 atttaactac tttttcaaca ctgaatgtct catcatttac attttctatc aatgctattg
     2461 aacacatatt atagccattt ttatgttcat caagtttgac aactaagtct gaatcttgtt
     2521 tttgtttgat tgttacaatt ccatcagctt cagaccagtt agctacacct tcgtatataa
     2581 aagcataaat aagtattctt tttatatctt ttattttatt accatttatt cttaaatttt
     2641 ctccttgtgt attacttcct gttctgtcat ctccatctaa ttgagcaaaa ggtggattgt
     2701 ctaaactacc aaaagcattt cctaatgctt gaacagcacc ttttacacca tttttcatct
     2761 caaataggca acccaaatct aaatctatat tactgcttct taaagagcca aaaaaaccct
     2821 ttttttgtac tttttgattc caatttaaat taactaagat ttcacctaaa tcgctatttt
     2881 ccttttttgt aaggtttatt ttttgtccct tttttaattc tatagccata gtaatcttcc
     2941 tccacaaaca tagatttatt taaatggtag cacttaataa gtcaatattc aacaagatta
     3001 gaataataat attaaaacta tactaaatat actaaaaagt aggaatcaca atacctttgt
     3061 atttttcttc aattaagctt cttgctttat ctgatgtaag aacatcttgt agaactttaa
     3121 tcttttcact gtctttatct tcagttctaa atgctaaaag atttgcatac tcgtcattta
     3181 taggagctgt ataaattccg tttttcttgg catcaagacc agcaggtaca gcataagtag
     3241 tatctataaa tgcagcagta acatctggaa gagaagatgg aatttgagca atatctaact
     3301 ctttgaattg tattcccttt ggattttcta ttatgtcctt aggactaact aatccatccc
     3361 ctttaggtaa cgttaaaagt ccaatacttt caaggtatct aaggttctta gagcaagaag
     3421 atgggttatt gcttattgca attgtatctc cttttttaaa ttcatcaaca gattttatct
     3481 tataagagta aagtattgct gggcatacat atagtttttt accagccatt attttgtaac
     3541 ctttggcctt aacagcttct tttagataag gttcatgttg aaatagattt gcatcaattt
     3601 caccattatt taaagcttcg tttggaagta tgtaatcatc aaagttttta acttctaaag
     3661 tatatccttt ttctttaata agtggtttta attcttctaa taactctcct cctggaacta
     3721 aagtagcacc aacaacaatt tttttatcat ctttagcttt agaacatcca accacagcta
     3781 aagttagtac tagacataat aacaaacata ataatttttt gaatttcata taaattccct
     3841 cctgaatata attgattagt taaaaataaa ataccattct ttatcacact gcaaaataaa
     3901 aataagcctg agtttaaact caggctttaa aagctaattt agactcatct ttcagtataa
     3961 tactgcagga tttagcacca atgtatataa aaatatactg gttgctgggt ttcatagggc
     4021 cagtcccttc accactctgg ataagaagta tcaattttta attatgttat aaatattatc
     4081 atgatttttt acgtctgtaa acataatttt ataaatattt taaaatcttt aatgtatttt
     4141 atttaacacc taaaattcca gaaactagaa tatcagtatc agcacctaag aaatagtcat
     4201 ttatttcaat agaatccaga gtatttctca aagcattttc ttcatgcctt ataccaataa
     4261 gtttattttc tacaaatgca acatcacatt ttccaaaaaa atctccaaaa aattttatac
     4321 tagttattat gcctttatca acatttaaat taaactcaac atttccacca gaatatttta
     4381 attcatttga aagagtatat tttggtgaat taccaaaatt ccaatcccaa gtttcgtatt
     4441 ttgatttagt aagcttttct atttgtttta tatcatgctc attcaaacaa taattagtat
     4501 tatcagtatt tgttttagaa agataatcca ttatagcatc tttaaattct aatatgtcca
     4561 tttttgaatg taaatgttca cttatattgg ttacacgaga ttttacagat tttattcctt
     4621 ttccttcaaa ttttataggt ttaaccttta atgcttttga gaggtcattt atttcagatg
     4681 aaaataaaag agtaccatga tgcattactt tgtttttgta gttgtattga gcatttccag
     4741 aaaatttctt gccatctata agaaggtcat ttcttccaga aaattcggca ttgacatcta
     4801 gtgttttaag taaatctatt atgggctgag tgaatcttct gaaatcacta aaattattat
     4861 tgttacaagc tataaatgta aaatttatat ttcccaaatc atgaaataca gctccaccac
     4921 cagactgtct cctaacgaca ggtatagaat attcttttat atattctaaa tttatttcag
     4981 aaagtgtgtt ttggtttttt ccaacaatta tagaaggttc attcctccat aaaataaata
     5041 agtcttcatc aaaatttttt agaagatatt cttccattgc taaattaaaa taagggtttg
     5101 ttttttcatt ataaattaat aacattaaag tagttcctcc atagaattga taaaattttt
     5161 attatgaata caattaattt tataattcga caataatata aaaactcctt taaattagaa
     5221 attttaaaaa ctaccttgca aagtttaaat aaataatata tactcaaaat atgtttaata
     5281 aaagtgaata gaagggtaga ggcgcaataa tctatcagta ctaataagga gttaagcaca
     5341 gagagttatt aggaaaggag atattgccga agttttataa tcgatgcttt aagattatat
     5401 tgctgggggt acatagaaaa tatgtacaac tgtcacaggt ttatttgtgg tgagctatca
     5461 tttaaggaat tatattatat ttatttttac tattgttgat atattgtaat gtttaagcct
     5521 tgagtgttta ccactcaagg cttttttagt tttattgtaa cataataccc tgtacagttc
     5581 acaaaattaa aaggagaggg agatttatat gaggaacaaa aaaattaata ttatttttct
     5641 gacgacaatc atgttcataa tgtcaacagt aatggttttt gcagaagaag atatagacac
     5701 tattgcacta gctaatgcag aaaaatttgg gattttaact ttaataccac cattagttgc
     5761 tataatactt gcatttataa ctaaaaacgt aataatttct ttacttatag gtattctttc
     5821 tggtagtttt ataattaaag ctagtggtat taatgttttt gcgacattta tacaggcatt
     5881 tttagattta gtagatagag ctttagtatc tttagcagac ccttggaatg cagggataat
     5941 actacaggtt ttggcaattg gaggagtaat aaatcttgtt gctaaaatgg gaggagctaa
     6001 agctatagct gaagcacttg ctaaaagagc aaagtcagca aaagggacac agcttataac
     6061 atggtttttg gggcttttag tattctttga tgattatgcc aattcactaa tagtaggtcc
     6121 tatgatgaga cctgttgcag ataaaatgaa aatatcaaga gaaaagctag catttataat
     6181 agatgccaca gcagcaccag ttgctggttt agctataata tctacatgga taggtcttga
     6241 ggttggttta atacatgatg cttttgaaag tataagtata gatgtagatg catttggtat
     6301 atttttaaat acaataccat ttagatttta caatatatta atattagctt tcattgtaat
     6361 atcagcatta ttattaaaag aatttggtcc aatgagaaaa gctgagataa aatctagaag
     6421 tagaaaaatt agtatagacc ttgatgaagg cgtagaagag ttggatgatt tagctccaaa
     6481 aaatggagta aaattgagtg tatggaatgc tataatccca ataggaacat tgataatagt
     6541 tgcattagca tcattttatt atagtggata tacatctata atgggaggag acgataaggc
     6601 tctgatacaa ctatttacaa attctccata ttcttttgaa gcaataaaag aagcatttag
     6661 tgcatctgat gcatctagag cattatttca gtctgcactt gttgcaagtt tagttgctat
     6721 tataatggct gtagtaaaaa agatttttac aatatcagaa gcaattgatg tttggataga
     6781 tggaatgaaa agtttagtaa tcactggtgt aatattaata cttgcatggt cattaagttc
     6841 agtaataaaa gagttaggta cagctaagtt tttaatacac ctattatcag gttcactacc
     6901 accattctta ttaccaagtt taatatttgg tttaggagca ataatatctt ttgctactgg
     6961 aacagcttat ggaacaatgg gtatacttat gccacttgca attccattag catactcatt
     7021 aaatcctgat atgtcttatg taatagtaag tactagtgca gttttaacag gtgcaatatt
     7081 tggagaccat tgttctccaa tttcagatac aacaatactt tcttcaatgg gagctggctg
     7141 taatcatata gaccatgtta acactcaaat gccatatgct atatttacag cagtaatcac
     7201 tattgtattt gggtatatac cagctggact tggattgcca atatatatag tattaccagt
     7261 ggcaatagct gctatatttg taggtattca aataattggt aagaaagttg atgaagcgga
     7321 aatagaactt gtagaataaa gatataaata agtttcacct tttattatca ctattttgtt
     7381 agtttttaga taattttaaa aagttattga aaataatggc gaaatatagt aaaataaaag
     7441 agtgataagc ggatgtggcg gaattggcag acgcactaga cttaggatct agcgccattg
     7501 gcgtgggggt tcgactccct tcatccgcac tttacagtac ttaattgtac tgaaaaaaac
     7561 tggggttgct ggctttcgga gtgggctatc ccgtttttat ttttttgtat atataataga
     7621 ttggcacttt agtataaggt gcttttttta taggcaaaaa cagtacattt atttctgttt
     7681 tattatcatt catctattag aatatacttt atttaagaat gtgttaataa gcagtgttca
     7741 cattcttgat aaaatgtgga ataatatgcc taccaataag catttggtgt ataagtaaga
     7801 gtatttatat agttgattgt gaaatgagta caacaattct gtacagtata attggcatta
     7861 taattgtagc attgaattta aagtttgcac agtcgctgat tggaaaattt acaaagtgga
     7921 tgtcaaacat ataaatttta gtttattgga cagttcaagg aatcagaaat tggaatttta
     7981 tagtattaat attttatagt attaatataa tgtataaaat tttatagcaa tgtatttcat
     8041 aagtataaag tgactagaat tttaagaaat atacaaattc tataaaaact aaataatttc
     8101 aagtatattt taaaaatctt atttttcaca agtttaaaat tgtaaacgat ttcatcaagt
     8161 ctatgaatat acttttaaca tgttatagta aatctcaata taaatttaca tttggttctt
     8221 tgtgtgttat tttaataata aattaagtga aaatgttatt ttacattaat atataatatc
     8281 tttgcataag agtgaataat ataaaagaga aagaattgat aataaaaact taacaaaaaa
     8341 attaatacat aaaaaaaaat aaatataatg tgttgacatt taattgaaat attcatacaa
     8401 taaaattgaa aataaatatt tccaaatgag attagcgaga gagtccttta tacgaaaagg
     8461 cgccgaagaa gaaatttaag aaatgccaat ttttagagaa gctttcaggc aaaaatatcg
     8521 ctaattgatg ggactctgga gagacttaag ttaagatact ataagtcacc gaagaagcaa
     8581 aataatatta aattattaaa tctttcaggt atacaaacag ggatatatag gctaggatta
     8641 ttttccatgc tgatatatct tttttttatg aaaaagtaca ggaaataata tcaaagttac
     8701 ttaaatacag taggtctaat tttctaggga gggttatata tgaatgaatt gaaaagagta
     8761 tctttgtaca atatacacaa agagcttgga gcaaaacttg ttgaatttgc tggctgggaa
     8821 atgcctttag aatatgaggg tataaataaa gagcatgaga aggttagaaa aagtgcaggt
     8881 atatttgatg tatctcatat gggagaggta cagataaagg gagcagagtc agaaaaattt
     8941 atacaaaacc tagttacaaa tgatataagc acattaaaga taaatgacat tatatataca
     9001 cctatgtgtt atgaaaatgg tggagtagtt gatgatttat taatatataa atttggtgaa
     9061 gaagattatt tattagtaat aaatgcaggt aatatagata aagatgtagc atggataata
     9121 aaacaaagtg aaggatacaa tgtagatata aaaaatatat ctagtgaagt gagtcaatta
     9181 gcaattcaag gacctaaagc agaagaaatt cttcaaaaaa tcacagatat agacttaaac
     9241 tcaataaaat tttataagtc aattccatca acaaaagtat gtggttgtcc ttgtttagtt
     9301 tcaagaacag gatatactgg ggaagatggg tttgagatat actgtaaaaa taaatatgta
     9361 gaaataattt ggaatgaagt tctaaaggtt ggaggagaag atatatgtcc agctggtcta
     9421 ggttgtaggg atactttgag atttgaagca gctctacctc tatatggtca tgaaataaat
     9481 gaacacatat ctccaattga aggtggttta tctatatttg tgaaaacaaa taaagaatca
     9541 tttattggta aatcaatttt atcaaaagaa aaagaaagtg gagctaaaag aaagttagta
     9601 ggatttgaaa tgcaaggtaa aggaatgcct agaaatggat atgatataag gattggtgat
     9661 aaaacagttg gatttgtaac aacaggatgt gcatctccaa cgacaggaaa aattttaggt
     9721 atgggaatta tagattctga atatgcaaaa gtaggaaatg aaataggtat agcaatcaga
     9781 aaaaaagttg ttcctgctgt gatagttaag aaaccttttt ataaaaaaca atataaaaaa
     9841 gataatatta tattaaacaa agaaaataaa ttttcatata tacctgctac aagtgaagat
     9901 aaatcaaaaa tgttaaaagt agttggatta aattcggttg atgaattatt ttcagatata
     9961 ccagaagaag taaaattaaa aagagattta aatttggaaa ttggaaaatc tgaattagag
    10021 gtaagcaaaa tagtaaaaag attgtcagaa gaaaacttaa gtttagaaga cttgacttgt
    10081 tttcttggtg ctggtgcata tgaccattat ataccatcaa ttataaaaca tataacttca
    10141 agatctgaat tttatacagc atacactcca tatcaagctg aaataagtca gggaacttta
    10201 caagtagttt ttgaatttca atctatgatt gcagaaatta caggtatgga aattgcaaat
    10261 gcatcaatgt atgatggagc aactgctgca atagaagcat gtataatggc aatgaatcag
    10321 actagaaaaa gtaaaatagt agtgtcaaaa actattcatc atgaaacttt gtcagtatta
    10381 agaacttact tacaatataa agattgtgag atagtagaaa ttgacttttg taatgaatat
    10441 gggactacag atatagaaaa attaaaagct tctgtagaca aggatacagc atgtgttctt
    10501 atacaaactc ctaatttctt tggaattatt gaagaaatgg aagaaataga aaagataact
    10561 catgaaaata aggctatgtt aattatgagt gtagacccaa tatcattagg agttttaaaa
    10621 acaccaggtg agataggtgc agatattgtt gttggagaag ctcaatcact tggaaaccct
    10681 cttaattttg gaggtcctta tgtaggattt ttagctagca aatctaaata tactagaaaa
    10741 atgccaggaa gaatagttgg gcaaagttta gatgtagaag gtaaaattgc atatgtatta
    10801 actttacaaa ctagagaaca gcatgtaaga agagaaaaag caacttctaa tatatgttca
    10861 aatcaagctt taaatgctct tgtagcttca atatatatgg ctactatggg taaagaagga
    10921 tttaaagagg ttggtatgca gtctatgaaa aaagcacatt atacttacaa taagcttgta
    10981 caaactggaa aatataagcc aatatttaaa ggtaagtttt tcaaagaatt tgctgtacaa
    11041 ggaaatctta atatagaaac tataaatgat aagctcttag aagaaaatat attaggtggt
    11101 tataatttag aatacaatta tccagaatta aaaaattcaa ctttgctttg tgtgactgag
    11161 aaaagaagca aagaggaaat agataagtta gttggaataa tggagggatt ataatgaaag
    11221 aatacaatag tttgttgata gatatatcta aaaaaggtag gaaagcatac tcacttccaa
    11281 agttagatat agatgatata aaaatagaag atatgattga ccaagatatg gcaagacaaa
    11341 gtgagttgaa tttgccagaa gttggtgaat tagaattagt tagacattat acattattat
    11401 caaataaaaa ctttggagtt gatacaggtt tttatccttt gggttcttgt actatgaaat
    11461 ataatcctaa aataaatgaa gatatggcag cacttccaaa ctttactgga atgcatccat
    11521 accaatcttc ggatacagct caaggttctc tttctttgat gtatgattta tcaagaagac
    11581 ttgcagaaat tacaggtatg gatgaagtta cactacagcc ttcagcaggt tctcatggtg
    11641 agtttacagg gcttatgatt ataaaagcat atcatgaaaa tagaggtgac cataagagaa
    11701 ctaaagtgat aattccagat tctgcacatg gaacaaatcc agcaagtgca gctatggcaa
    11761 actttgatgt gattcaaata gcatctgata aaaatggagc tgtagacata aatgcattaa
    11821 aagaggtttt gaatgatgaa gtagcagctc ttatgcttac taatccaagt actcttggtt
    11881 tatttgaaaa aaatataaaa gaaatagcta ctcttgtaca tgaagcagga ggacttttgt
    11941 actatgatgg tgcaaacatg aatgctatta tggggataac aagacctgga gatatggggt
    12001 ttgatgtggt tcatcttaat cttcataaga ctttttcaac tcctcatgga ggtggaggtc
    12061 caggagctgg tcctgttgga gttaaaaaag aattagtacc ttttttacca ataccattaa
    12121 ttgaaagaaa agaagataag tatgtactaa attatgatag agaaaaatct attgggaaaa
    12181 ttaaaaattt ctatggtaat tttggagttc ttgtaagagc ttacacatat atactaacta
    12241 tgggaaggga tggacttaaa gaggctagtg aaatggcagt tttaaatgct aattatataa
    12301 aggaaagtat aaaagatgat tatattttgc caatagatac cttgtgtaag catgagtttg
    12361 tattaggtgg attgccaaga ggagaggcca atataaaaac tatcgatatt gcaaaaagac
    12421 tactagatta tggataccat cctccaacaa tgtactttcc tcttattata aatgaggcac
    12481 ttatgataga acctacagaa agtgagagta tagagacatt agatagtttt atagaagcta
    12541 tgaaaagtgt tgctaaagag gcaaaggaag aaccagaact attgaaaact gctccacata
    12601 atactttggt caaaagagta gatgatgcaa gggcagtaaa gaaacctata ctaacatggt
    12661 cacaaagata aataattaaa aagtagagat ttaaagtata aagagaatta aatttgtaag
    12721 aaaaagctat ctaacttaat ccagtttaga tagctttttt gtatattagt atgtatggta
    12781 ttttctatat aaagttttaa attatattag tgcttatata gaatattgat atgatgatta
    12841 tgtatagata ttaataagaa ttgttgaatt tatcttgcct taactttatt tactctttta
    12901 tcttaagaaa aacttaacta aaatatagcg aaattcataa aaatttagga aatcttaaga
    12961 attataata
//
LOCUS       DAMJWO010000098        12859 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.101, whole genome shotgun sequence.
ACCESSION   DAMJWO010000098 DAMJWO010000000
VERSION     DAMJWO010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12859
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.101"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            123..311
                     /locus_tag="PC366_003186"
     CDS             123..311
                     /locus_tag="PC366_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HDF2578677.1"
                     /translation="MAKVCSVCDKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            complement(471..623)
                     /locus_tag="PC366_003187"
     CDS             complement(471..623)
                     /locus_tag="PC366_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HDF2578678.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(721..1197)
                     /locus_tag="PC366_003188"
     CDS             complement(721..1197)
                     /locus_tag="PC366_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDF2578679.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDIIYKVFSKSGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            1416..2177
                     /locus_tag="PC366_003189"
     CDS             1416..2177
                     /locus_tag="PC366_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2578680.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKEHHNKLLAKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIREKYGKDIIDTSNKKLKNMSK
                     QDYENWQNLNIEIISKLKKAFKTGDASSELAQEVAKLHHKWLSYTWNTYSKEAHSSLA
                     QMYVYDERFTSYYDREQPGLAKFLRDAIVIYTRDK"
     gene            complement(2437..4365)
                     /locus_tag="PC366_003190"
     CDS             complement(2437..4365)
                     /locus_tag="PC366_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDF2578681.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSING
                     TLEKNGAIIKIKKGEGYYIDILNLALYQQYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQRVVLSEINKFNINFLDFNLK
                     NFIIHLAITISRILDGYCLDNVLDVVLTDFQSNTTVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRVDTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEITLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQNNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSHIYSNLLDNFFDKNLF
                     IVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMELS
                     SIRTKICISILNEPIYWSEDSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNDFDNFLSIIKSIV"
     gene            4599..5051
                     /locus_tag="PC366_003191"
     CDS             4599..5051
                     /locus_tag="PC366_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDF2578682.1"
                     /translation="MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGIATNKEALLKDL
                     LKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HKNEGNIHLKTLSKLATCLMEDDFTSEVKNASDASHLVKYITNKMKEE"
     gene            5054..5362
                     /locus_tag="PC366_003192"
     CDS             5054..5362
                     /locus_tag="PC366_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDF2578683.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
                     "
     gene            5476..6582
                     /locus_tag="PC366_003193"
     CDS             5476..6582
                     /locus_tag="PC366_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDF2578684.1"
                     /translation="MSKKNKSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAM
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPAMGAGFIGGL
                     IASNTNAGFLGAVIAGFFAGYVCKFLKKKIKISGSASGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGAMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSKFSNALAETGKGNIVMGIIGITEGAI
                     PFTLTNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISIGSGWAYLVGAIF
                     GALVIAILSTTLVDFNEDETTENTEFDEIELDIM"
     gene            6657..9335
                     /gene="mngB"
                     /locus_tag="PC366_003194"
     CDS             6657..9335
                     /gene="mngB"
                     /locus_tag="PC366_003194"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HDF2578685.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNG
                     FDQAPIRKNLPDILKKANEIDNENEYEISNIENYIDSVKNERNEFTELKGEFLNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENA
                     AHDSIGSCNSDTANEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGF
                     PEVRNEVVEFDTYIPGQDFVIKNKNGEILNYIIKEKEDITNYILTQTIRLNPSKKIYI
                     PKTVYRAKIALSVKDIPPMGYTQLVFELDTKNKCEIETSNCKEIENKYYKITANKNGS
                     LEILDKESSKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNIQEE
                     MILKYSLTIPASLEERSIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLLFAFNDEKQ
                     IYENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYS
                     AMLDEIYDNNSKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(9652..11985)
                     /locus_tag="PC366_003195"
     CDS             complement(9652..11985)
                     /locus_tag="PC366_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2578686.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQAGAKGGA
                     KNPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSDENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKVINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKVISKGDSVEYGY
                     GNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLL
                     RIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIREYFTKHTVTGMFFVWLKKAGKTVINQIRTINLK
                     EKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSGD
                     VYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(11960..12676)
                     /locus_tag="PC366_003196"
     CDS             complement(11960..12676)
                     /locus_tag="PC366_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2578687.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMRLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVNIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAINTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
BASE COUNT         4798 a         1790 c         1662 g         4609 t
ORIGIN      
        1 taagaaattc ttcaatatgt gtaaggcaaa tatatatttc tattgcaaat ttttgttatt
       61 tatgataata taaatatgtt tttagtcttt aaatagttat cattttaagg aggtgtgcgt
      121 agatggcaaa agtatgtagc gtatgtgata aaggtaaggt ttctggaaac caagtatcac
      181 actcaaataa acataataaa agaacatggt cagctaactt aagaagcgta agagcgatta
      241 tagatggagc tcctaagaga gtaaaagttt gtactagatg tttacgttct ggtaaaattg
      301 aaagagctta gtaaccacgt ttaaaagcct acttccgtaa gtaggctttt taatttaatc
      361 atttttactc tttctcataa attttaggat tatacttgaa atccattttg gtaattttat
      421 tgttactact ttcatcaata ctcaccccac actttatagt taaaactatt ttaacaaaaa
      481 aataataatg ctccacatcc aataagtatt aatgcggtaa gtgctgacca aatccagcca
      541 ggaagcaaca ttgacagaat tacagccatt cctgttgcta gacaaagtat tcctagcaat
      601 accttagact tgttatttct catggaacac ctccacatag aacctgtatc tataaatatt
      661 ttcatattca agtttatgcg acagttttcc attttagacc aataaacaca ttatgtaatt
      721 ttaatttttc atactagaat tattactgaa ctccgatata gattctacaa tatccaaaat
      781 tccttttttt ctacttaacc tttcaggtcc actatataaa accactggta taactttagg
      841 aagtttaaaa tttttatctt ctatttcttc aaggcttttt ttcataataa aacttttcca
      901 aatttgttct ctatacgatt tcaatcttgg gacaatttca gtatccattt ctgtttgaaa
      961 ttctaacact atataatgtg atactttgcc acttttagaa aataccttat aaattatatc
     1021 aacttctttt cctttatatt cacatataaa agatgtttct aactctatat ttttaagagt
     1081 taattctttt gctattgaga cacttgtaaa attttgaatc aaacttaaaa aactttcttt
     1141 atctgaatac attcttctgt actcttctcg tttttcattg cttcttttta aattcataca
     1201 gttcctccta ggctatagac cttctatatt ttagtaaaga tagtctataa attttatttt
     1261 ttaattttca ttagtgagta ttgacagttg tgtgtaaaat atccagtaaa gatatttttt
     1321 tatattttta ttaaaagata taaattttta tattttaata tattgacatt tacgttgcgt
     1381 aaaagtgtat atttaattta taggaggtat tacttatgga atatacagtt caaaaattaa
     1441 gtaaactagc tggtataagt actagaacac ttagatatta tgatgaaata ggtcttctta
     1501 agccacttaa aataaattct tcaggttatc gtatatatgg tcaaaatgaa gttaataaac
     1561 ttcaacaaat acttttttat agagaattag gaattaactt agaaaatata aaaaacatta
     1621 taaattcacc aaacttcgat agtttaagtg cgttaaaaga acaccataat aaattactag
     1681 ccaaaagaaa gcaaattgat ttactaatag aaaatgtaac taaaactata gctctgaagg
     1741 agggaaaata cactatgaca gatatagaaa aatttgaagg ttttaaagaa aagatgattg
     1801 atgaaaatga aaaaaattat ggaactgaaa ttagagagaa atatggtaaa gatattatag
     1861 atacatcaaa taaaaagctt aaaaatatgt ctaagcaaga ttatgaaaat tggcaaaacc
     1921 taaatatcga aataattagt aaacttaaaa aagcttttaa aactggtgat gcctctagtg
     1981 aactggctca ggaagttgca aaattacatc ataaatggtt gagttacact tggaacacat
     2041 actctaaaga agctcattcc tctctagcac agatgtatgt atatgatgaa cgttttacat
     2101 catattatga tagagaacaa cctggattag ctaagttttt aagggatgct atagtaatat
     2161 atacaagaga taaataatat aaaataataa aggtggtgtc tcaaaatgaa ctttttagtt
     2221 catgagacac tcttttttgt atgaaatcaa atatattttt atcattttat caatgaaaaa
     2281 caagtttctc tctctatttt gagacagaat ctttattgta taataattat aatcaataca
     2341 aaataataac aaattataca aaacttactt atactattta tgctaaaaac aaaaaatatt
     2401 ttattaaagt ttttaaaact tatgtaatat aaaaatctat actatagact tgattatgga
     2461 aagaaaatta tcaaaatcat tacaattaga tatactatct ctaatatcat tgtcatgaat
     2521 tatctttaaa aggatatcat aaatggagtt tatttttata taatcatctt tatttatagc
     2581 taacatcatg attaatttaa cagtagaatc ttcactccaa tatattggtt cattcaatat
     2641 ggaaatacaa atcttagttc ttatagagct taattccata ggatgaggta tagctaaaaa
     2701 atcatctata ttggtagaag ataaactttc tctgtaaaat acagattcag caaatgatgg
     2761 aaatacaatt tcactttgag ttaatttgtt gcacatcaac tttataagct catctttatc
     2821 tttgatttta ggattaacaa taaataaatt tttatcaaag aaattgtcca aaagattact
     2881 ataaatatgg gaattattag tgattgactt agatatattc tctatatctt tttttaatag
     2941 ttttaaatcc actaatacaa taggaatact atcatgattt aaaggaattg tcgatattat
     3001 tatatctaca tctgacaatt cactagctaa aaattgatta aatgatagac attgaagtat
     3061 atttatttta tcatgaaaaa ctttgtttaa ttgaacctct aataacctac ttgaaccata
     3121 ccctgaacca catactaata ctacgttttt acacttaata ttattttgaa aaaatctctc
     3181 tattccagca cctatatgca gggatacata tccaatttca tcttctgtta aagagtaaat
     3241 actattttta aaaacttttt ctatagcatt taaagttatt tcaaatgcta aaggataatt
     3301 actctttatt gtatttataa ggggattcac cttatttaaa ttataagatt tagaattgag
     3361 aattgattta aagtgcagta ctaaatcatc aaataataca ctatcatttc taaggtcaaa
     3421 agtatattga ttgttgatta cttctaaaat ttcttcaaca tactctataa ttttagtatc
     3481 caccctattg gaaacgttat ccaaaagaga acttttagtt ataaaatgat tatatagata
     3541 aactctgtct gcctttgaaa taattatagt atatttactc tcaatataat taaatatatt
     3601 ttcaacagtt gtattcgatt gaaaatctgt taaaacaaca tctaaaacat tatctaagca
     3661 gtaaccatca agtattctac ttatagtaat agctaaatgg ataataaagt tttttagatt
     3721 aaaatctaga aaatttatat taaatttatt aatttcactt aacactaccc tttgaagctc
     3781 tattaaatct acattattaa ataattctat ttctctatct gtaattccaa ttatatagtt
     3841 ttcaaaattc ctatttatca tattattaga aatacatctt cgaatatcta tttccttccc
     3901 ttcaacttta actccataat atggcttaga aactaatatt aaattatact ttgacaaaat
     3961 aggctttatt ctttttatgt catttagtat tgtaaattta ctcacataca agctattagc
     4021 taaatcttct agttttatat atgtattgtt atagagaata tattttaaaa tatattgatt
     4081 tctttctata ggagaatctg gtatttcact tgaatccata atatcatcag atattaatgc
     4141 tagatactgt tggtataatg ctaaattaag aatatctata taatatcctt ctcctttttt
     4201 tattttaata atagcaccat ttttctctaa agttccattt atagaagtaa tatcatttct
     4261 tatagttctc tcactcactt ttaaatgatt acttaaagtt ttacaagtaa ttttatcatc
     4321 actttcattt aataatttaa acaacgtgag caatctcttg tgcataaata tcccccctta
     4381 tagaatttct tctaaattat actatttaca ctcatataat acaattactc taataaaatt
     4441 gtattataat aatttctttc cacttctata tggaaattag ttattatcat aatataaatt
     4501 tccatgtcga agtggaaatt agttatattt aatttaatta ggataatgat tacaatataa
     4561 atataagtta agacattacg aatggagtgg aaaaatatat ggtactacaa gaaaaatata
     4621 tatttataga taaagactta aaaagcaaag aagaagtatt aaattttatt gcagatagtg
     4681 cttatatact aggtattgca actaataaag aggctctttt aaaagacctt ctaaaaagag
     4741 aaaatgaatt tccaacagga ataaaagatg gatttgcgat acctcataca aaaagtgtaa
     4801 atgtaaagga agcttccata ctctatatta aaacaactaa cgagttagag tggaaaactt
     4861 tagatgatag taaggttaga tatgtattta gtttgttagc cccacataaa aatgaaggaa
     4921 atatacattt aaaaactcta tctaaattag ccacatgttt aatggaggat gattttacaa
     4981 gtgaagttaa aaatgctagt gatgcaagtc atttagtaaa atatataact aataaaatga
     5041 aggaggaata attatgaaaa tagtagcaat aacatcatgt atagcaggat tagcacacac
     5101 acctatggca gcaaaagctt tagaacaagc tgcatcaaaa atgggtcatg aaatcaaagt
     5161 agaacaacaa ggtgctatgg gacgagtaaa tactataaca aaagaagaag cacaagatgc
     5221 ggactttata cttatagcat ctgaccaaac tatatctgga atggaaagat ttgatggtaa
     5281 aaaagtgata aaagtcaaaa taggtatagc gttaaaaaaa ccagaagctg tcttaacaaa
     5341 gtgtatagaa gctatttctt aataaaaaaa tctcactcta atatagaatg agaaaaataa
     5401 aaaattaaaa aattgtctaa tgtaattata acatattatc aaaaaatata acaaacttat
     5461 ataggaggat taaaaatgag taaaaaaaat aaatctcttt taagtgaact taagggacac
     5521 ttaatgacag gtatctcata tatgttgcca cttgtaatag gctcatcttt agttgtagct
     5581 atcccaaagc ttacagcttt agcaatgggt ataacaagtt tagatgctta taaaaatgta
     5641 tctggttttt atcatattct ttacttaatg gaacaagttg gttggactgg cataggtcta
     5701 ttaaatacgg tattagcagg atttatagca ttttcaatag gtgagaaacc agctatgggt
     5761 gcaggtttta ttggtgggct catagcaagt aatactaatg caggattctt aggagcagta
     5821 atagcaggtt tctttgctgg gtatgtttgt aagtttttaa agaaaaaaat taaaatatct
     5881 gggtcagcat caggaatgat gccacttata ataatgccac ttataacagt tggattaact
     5941 ggttttttaa tgagtgttgt attagcagga cctttaggaa acataaatac ttcattaaat
     6001 gcttgggtag ctgaaatgtg tcaaaatgga acaaattcgg tggtattggc tttaatttta
     6061 ggcgcaatga taggattcga tttaggtgga ccagtaaata aagcagcttg gatggcagga
     6121 aatgcattat tgttagaggg aatctatcta ccagcgatat tggtaaactg cgcaatagtt
     6181 atacctccac taggatatgg tttagctaca ttcataagaa aatcaaaatt ttccaatgca
     6241 ttagctgaaa caggaaaagg caatatagtt atgggtataa ttggaataac agaaggtgca
     6301 attcctttca ctttaacaaa tccattaaaa ttagttcctg ttaatatgat aggatgcgct
     6361 ttgggtgtag gattatcagc tttgttaggt gtacatgcta taatgcctcc agttggtgga
     6421 ttatatggat ttatatcaat aggttctgga tgggcttact tagtaggtgc aatatttgga
     6481 gctttagtaa tagcaatatt atcaacaact ttagtagact tcaatgaaga tgaaactacg
     6541 gaaaatacag aatttgatga aatagagtta gatataatgt aaattaaaaa cttaatttta
     6601 gataattgag aattgagtgt actctcaatt ctcaattaaa ttttgggagg atttttatga
     6661 aaaagacaaa agtacatgta gttccacaca gtcattggga tagagaatgg tattttacaa
     6721 catcaaggtc aaaaatatat ttaatgaaag attttcaaga tatattagac atattggaag
     6781 aaaaagagga ctttaaatac tttactatgg atgcacaagc ttctctctta gatgattatt
     6841 taaaatggag acctcaggat gaatatagaa taagagattt agttcaaaga agaagattag
     6901 ttattggacc ttggtatact caaacagacc aattggttat atcaggagaa tctataatta
     6961 gaaaccttta ctatggaata gatagatgca atgaatttgg tgaacctatg agggttggat
     7021 atgtaccaga ttcttttggg caatcagctc aaatgccaca aatatacaga ggttttggaa
     7081 tagatagttc attattttgg cgtggagttt ctgatgatat ggtagataca acagagttta
     7141 tatggaaagg ttctgatggt tcaaaagtat tagcagttca aataccattt ggttattact
     7201 atggaggtaa tataccagaa gatgattcag atttaaaaga atatttaaaa gatataattg
     7261 gaaaacttaa ggttaaagct tctactaata acgtatattt tccaaatgga tttgaccaag
     7321 caccaataag aaaaaacctt cctgatatat taaaaaaagc taatgaaata gataatgaaa
     7381 atgaatacga aataagtaat atagaaaact atatagattc agtaaaaaat gaaagaaatg
     7441 aatttacaga gcttaaaggt gaatttttaa atgctaaaca tatgagaata cacaaatcca
     7501 tattctcctc aaggtcagac cttaaaataa tgaataacaa attagaaaat tatatcacaa
     7561 atgtacttga accattatta acattaagtt attcacttgg aaatgaatac cctcatctag
     7621 ttataaaaga tatatggaaa cttatgtttg aaaatgcagc tcatgacagc ataggttctt
     7681 gtaatagtga cacagcaaat gaggatgtat acacaagata caaacaagcc agagatttga
     7741 gtataaattt attagatttg catatgagac ttataagtac tcaaatcaaa aataataatg
     7801 aagaaataac attaacagta ttcaatggat tcccagaagt cagaaatgaa gttgtagaat
     7861 ttgacactta tattccaggt caagattttg tgataaagaa taaaaatgga gaaattctta
     7921 attatataat aaaagaaaaa gaagatatta caaattatat attaactcaa acaataagat
     7981 taaacccaag taaaaaaata tatataccca aaactgtata tagagcaaaa attgcacttt
     8041 cagtaaaaga tataccacca atgggatata ctcaactagt ttttgaattg gatactaaaa
     8101 ataaatgtga aatagaaaca agtaattgca aagaaataga aaacaaatat tacaaaataa
     8161 cagccaataa aaatggttca ttagaaatat tagataaaga atctagtaag acttataaaa
     8221 accaagctgt aattgaagac aatggagatg atggagattc atacaactat tctcctccaa
     8281 gaaaagatat ttatgtttca tctttagatt ctgtatcttc agtagaagtg ctaaaatcaa
     8341 atattcaaga agaaatgata cttaaatatt cattgaccat accagcttca ctggaagaaa
     8401 ggtctatagg taaagtttct gtgaaaatgc cagtaacaat gaaaattacc ttagaaccta
     8461 aagaacaaat aattaagttt aatgttaata taaaaaataa ccaagcacta tctcatagag
     8521 taagagtttt atttaataca gaaatagcat ctaagttttc tatagcagat caacaatttg
     8581 gaataataca aagaccaaca gtattagaaa aagaccttgc attatggaaa agagacaatt
     8641 actcatggca agaaaaacct ataactatcg aaccaatgca aagttttgtt actttagagg
     8701 atggacaaag aggaatagca ttaataactg gttgtgtaag agaatatcaa atagttggtg
     8761 ataatttaga tacaatagca ttaacactat tcaggtcatt tggatatatg ggaagagaaa
     8821 atttacttta tagaccagga agagcttctg gagaaaaaat aatagcaaca ccagatgcac
     8881 aattacttaa agagttaaac tttgactttg gtctttacat atataacaat aaatttgatg
     8941 aagcaaatgt agctaataca gctaagagat tcttaacacc tatacaaata tatgaatatg
     9001 ctgatttttt aaatggtaga cttctatttg cattcaatga cgaaaaacaa atatatgaaa
     9061 atgaatttag tttgatgaat gtaaataatt caaatttcac agtaagtgca ataaagaaag
     9121 aagaaaaagg agatggaatt gtagttagaa tcttcaatgg tatgaaaaat gaggatgcta
     9181 agggaagtct taacatcaat aaaaatgtca atgatgctta tagtgcaatg ctcgacgaaa
     9241 tctatgataa taatagcaag cttaaagtaa atactaaaac tgtagaggta aattctttat
     9301 cacattgtaa agtacaaaca atagtaatta aataatataa aatagcttat acaagatttc
     9361 aaaataaatt gctagtacta tgttaatagt aaacccagat attatgctat ttataagctc
     9421 tgtaacacta aataacattt tgtaaaataa aaaggtgaac cttgtatatt aggattcacc
     9481 ttttttaaat aaatcaacat tctgttttaa aataacattt ataagctgtt ttgaaataat
     9541 acttacaaat tattttaaaa caatacctat aaatttttat ttaaagaata cacataaata
     9601 tttccagact cttttattct atagacttta taattattaa agaagtctaa tctaattttt
     9661 gttaaaagta attgtaactt taaataaatc accatccaca cttatattca tcttaccacc
     9721 ctgtaattct ataaaacttt ttgctattgc taaaccaaga ccagaacctt ctgtgttacg
     9781 tgatttatct cctcttacaa atctctccat tatatcatct acactaaaat caatctcaga
     9841 tgcagacata tttttaagca taatatttac tttattatct gtttctaaaa tatcaatata
     9901 cactcttgaa tttggcattg catatttgct tatatttatt ataagatttt caaatactct
     9961 aaatgtacgc tgactatcta atggtaatat tattttttca ttagaaaagt tattctttac
    10021 tattagagat gaatctgcaa gtttgtcatc taattctaaa agtgtctgct tcattagaga
    10081 tacaatatcc acatttacta tattcaaata aacatctcca ctatttgcct tgcttacttc
    10141 aaacaaatct tctattagat gttgcaatct ttgtgacttt ctgtctaatg tatcaatata
    10201 caacttacga ttttcatctg ttatactttc atcttttaat aaatctatat aagtgattat
    10261 agatgttaga ggtgttttta agtcatgtga tacatttgat ataagctctg ttttcatctt
    10321 ttgactctta acctcttcgt caacagcttt tttaaatcca gtttgaatat ttcctaattc
    10381 gtcttttata ggattaaaaa atcctaaatc tttttccata tttacatcta agtttccatc
    10441 tgaaattttc tttgtaacat ctaaaagttg attatattca tatattgtct ttttagagta
    10501 atctgacagt atcttaaata atactactga atatattaat gcgagtatta ttccaaagaa
    10561 ccacatacta cacattataa ctataatcaa taaatttatt cccaaaattg taactatagt
    10621 tttatttggc ttttctttta gatttattgt tctaatttga ttaataactg tttttcctgc
    10681 tttttttaac catacaaaaa acattcctgt cacagtatgt tttgtaaaat actctcttat
    10741 tccaacattt aaaatatgtt ttaaaagtat tataaataca aatattattg agaatattac
    10801 aaaccaataa gttaaattca ttaaacttac caatatgcta gccattttag cacttatgtc
    10861 attgtttata aggtactcta cataattccc actcaaggta ttacttatta taacagtagg
    10921 atataaatct acaagcccct gtataatagc aagagcaata aagagtatct ctaacggtat
    10981 tcttaataat gtatcaaatc ctagcaactc tttagatttt ctatatggga atgctaaagc
    11041 tacaataaca actatagcta atataatttt taaaatcatt ccagaaatct tataataaga
    11101 attattttct acattgctta tatatgaaat tataccatca tcaaaataag tatttccata
    11161 accatactct acactatcac ctttacttat tactttaggt acagcatata ctaatgttat
    11221 attttttatt ggagataact tatatgaaat tgaatttcct cctaaacttg tatccattaa
    11281 atcttctctt gctttagata acaacatttg attaataact ttttgattta ctccataaga
    11341 atccacaata tttacttttc catctttatc aaaattcatt acaacgtaga atctatagtt
    11401 ttcctttata tctgtaatct gcttttgtct ttcctcatca ttcatttctg tattttttga
    11461 ctgattttca tcagaatttt cttttgaagc atcattcttt gttgtatcaa gtactcctaa
    11521 ttctttatta tcattaaaaa attcaaaatt gctttcttta tcaactaaat agtactttaa
    11581 attctttcct gacgctttaa tgaaatgctc ccaattttca aagttttcat taaaatctgc
    11641 attaatacta tcatctgtat aataagtttc tgaaccatca taagtatctt tttctttact
    11701 tacatttttt atatagttca tagtttcttc attgataaat agctttgatg gttgtatcat
    11761 cttaccttct tgttcttcct tcatattatg atataaaaca taacttcctt tatatatact
    11821 atctacaaag ctttcctgtt caaatggatt ctttgctcca cctttagcac ctgcttgtat
    11881 agtagaatat tgactaatca tacctaatga tgctgataac ataagtataa aaactataat
    11941 agtaactata tatttatctt taaatttttt caattttgta tccaacaccc cacaccacct
    12001 ttaaatattt aggatttttt gggtcaattt ctatcttttc ccttatattc ctcacatgta
    12061 ccataactgt atctgtattt atagcatttt cattccaaac tctttcatat atttcatcag
    12121 cagaaaaaac tcttcctgca tttctcataa gtaaacttag tattttaaat tctataggag
    12181 ttgtttttat atattttcca tcaatattaa cttcttttgt attttcattt aattctaatc
    12241 cgcctattgc aaacacacta tcatcacttt ctaccttttg ctctttattt ccaaccatgt
    12301 ttagatactt agtgtacctt ctaagttgtg aattaactct agccaatagt tctaatggct
    12361 taaaaggttt tgttacataa tcgtctgctc ctatattaag ccccattatt ttgtcaactt
    12421 cttctgattt tgcagatagc attattactg gaaaattata gttttctcta agcctcattg
    12481 taagtgttat accatccatt ttaggcatca ttatatcaac tatagctaaa tgtatttctt
    12541 ggttttctat aaccttaaga ccttctaatc cattgtatcc cttaaaaaca ttatatcctt
    12601 gatttaatag atatatctct atagcatctg cgatctcctt ttcatcttct accaccaaaa
    12661 tattatatga attcatttta atctccttta tattaattta taaattttct ttacatatat
    12721 gattatacaa tatgatagaa gtttttccat ttatatatat atttatatct tttgttctgg
    12781 ttatttgtat ttaatgtcca tcttagaaac ctccttctag tttaaactta atattttttc
    12841 attttgtttt atatactta
//
LOCUS       DAMJWO010000099        12702 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.102, whole genome shotgun sequence.
ACCESSION   DAMJWO010000099 DAMJWO010000000
VERSION     DAMJWO010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12702
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.102"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(142..2022)
                     /locus_tag="PC366_003197"
     CDS             complement(142..2022)
                     /locus_tag="PC366_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp10"
                     /protein_id="HDF2578688.1"
                     /translation="MSKRKSFIRTIAVSTMAVAVTGSVTCAYAAPVLQGTKTYEKVNT
                     IDISVDSVENIVYSFQASIKVQGEVEVVDNEQKEKITWSDNIKSQIKSGNANATCRVE
                     YNKSSNTTTLDIYVTSNEDLLDGNRLNIGRISVKKSGSNSNADYKVLGKGTSDKPALK
                     IVTYNNKTVDYENINSDEGLIFTLINESEVKPIGGTGSSKNDPEKYKVEKSEALEYLL
                     NNIRINYSIVSKETQESGSNVILKLGLAQKITKGRKATINKYVEVTLPKSLEYIVENE
                     LSKPDELPPDNGNGGNNGGGSNSGGSSSGGSSGGGSSSNSTSNVTVKKLKGADRFETA
                     TKISQSGWTKSDTVVIVNGEDKSMVDGLTATPLASVKNSPILLSSNEKLPQKTVEELK
                     RLNPSKVIVIGGNNSMPNSVVEAIKAVNSKISVQRIGGDTRYQTSINIAKEIDKTNNV
                     SKLYIGAGNGEADSLSIASLAGKEKTPIVLTQKDGVDNEAVQFIKSNKVSNIYFIGGI
                     EKISNKAIEQVGKIANKDISNNRVAGQTRQETNAKVIDKFYSQSKLDGVVVANQDKLI
                     DALAVGPLAAKNNSPVILATNTLDKSQESSLKGKNSSKLFEVGGGIASSVVDKIKSLI
                     EK"
     gene            complement(2232..8195)
                     /locus_tag="PC366_003198"
     CDS             complement(2232..8195)
                     /locus_tag="PC366_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin type III domain-containing protein"
                     /protein_id="HDF2578689.1"
                     /translation="MKKAISCVLAVSMCSAPLNVFAEPILEGKLRAVEKSVTEKLRGN
                     LEVDLNFSLPIKNSESESMTNMQLRLKDDSNNSGIIKLGEKDSGTVNIGTDNIEYTIK
                     KLSASRSEIKNKDENVSYYNIVFNNLPVGKYNIEVSGAGFKNKEIKDIDISSYSQRVL
                     LSNRASVDNKNKPLNYELFLMGDVNGDGKVDKSDYNKVLENIDSNKREFDLNRDGKVD
                     IVDLDYVQKNLGQSEDAKSLESIVSTNPIVDTSKVELKGNSDVDINGNVENLFSGENN
                     GVTISSKNDEISEEKPAVMDIALSEALNMEVINIKAPEGTAPAKGIVEVTDEDGNVQQ
                     IPYENKEYMKNLKDKEQQEEVNNEQEEVNQEEVNNKDENKNQTDNNSNNKDENNDKQQ
                     ENSDKQEVNSNTNQDKNNDKENSSMDKPNSDEDTPKEGDNISKDDNSTTSTYSRAALE
                     TYTDVQNSDIVINLGKQVAVKKITIKITATTANDRNLAEISKVEFLNNVYKEIPKPEM
                     NIPKINKISTSTAVGNEKVSFYWNNEVNVSAYELILDKIDSKGKVLSTKKLQTSKNTI
                     EVRDIEAYGLYRVSIQSLNGDWSSGYKDATPENLDGVPENVDSNYKPIQFSPDSILEF
                     QVVPDTKPEPPEGINVKGKFKSLDVSWKNHKQAKDFDLYYKEKGSNGSWIKYNDKLIR
                     GTSLKIEGLKDNTTYEVRMTATNHLGTSGMSKTYIGTTESIDAPTTPNYRLINTPKEN
                     GGFGIPTNHIVDVVYPAGYDKSEYSDKNPFDKFNVVDGDFTTHWTFPTYNAAEGTNRG
                     PIITFDKSYTMDTFMATPRFDVSDKTINDFEIRYWDENGQLHNLGDVPFETKTDPVNN
                     NKYVMVRLKEPITATKIQVSVCSSYSYKSNISELKFYEYDSIEDDVRNLFMDDLQVEL
                     KEDVTQEKITELKDRLNTPDKASGEYHPYKTVIDRELKLAQDLYNDRATLTDVTTVNQ
                     EINKSGKYKDKNGQYTVNSNNLGMQNDWQALGVAARAGDEITVYVGSKSGKTPKLIYT
                     QYYGESGAYKSGEINLKTGKNVIQLSKLHSLDIECGGSLYIRYPEDTPSGGDIKVRVA
                     GATKIPHLNLNGTINDKSPAGVSESKKKIKAYIEELAKYKDAVKGEPYYPGTNIGNSY
                     EYSEKTGVLNTTDIESDKVTLNVPATAVYQGISKGNADLNTQVDRLYNSMLAWEQIMD
                     LVYSERGVFKTQDLDGNGTVDDNEFNLTKNDMAPKSRMNIKYQRMFIGAFMYASGLHV
                     GVEYGSVPGLMNGVPFQIDDSGKATGGNLFGWGIGHEIGHVTDIGKMTYSETSNNVLA
                     LLAQTFDDKTHSRLEGSTMDKIYEHVTSNSLGIPSNVFERLGMLWQLHLAYDDDFTGS
                     MLKNNSDADLSNDTFYAKISRKYRALSSSDPINSLPKDQMLVAMASSVVEKDLRDYFK
                     AWGVEITPELNSIMDSKNYEKESRKIQYVNDEARRKILNENIASMAKDTKVSASFSDG
                     IQSGSLVKSNKISIDLDVDKDKDKILGYEIIRSDGNYLDGENGTQVKYRTVGFVDAKG
                     NSKAKFTDSISPLNNRAFTYKVVAYDYHLNPTEEFEVGTVKLSDEGKINKSAWSFITN
                     TVSDGDVRTENDSHGPLQNPEIDNIKDNDVSTTYKGKIISKAEWNKDPQKDPDINVEE
                     NPYIIVDMKETLPIVGLKYTKPEAETRKFSLKGLFNFRKNTSTTYNPLTNYKIQVSND
                     KKNWEDVSQGTFEYGQDLVGGGKDQDNEARVTFNKDDKLWTYQARYVKLISNNKSNIE
                     VAELDIIGPPGDNIEIGTMNNADQTRTNGIGKLAEDYVYQSDDPSTSEDETGKIPAGS
                     IIITGEYSGNPAFNLPLLIDKNNKTISGEALLFAEVPEKGELGEISKGTWVYYMPKEN
                     FDSLSDKVKAELYRYNDLQGDTPVGQRFVSDTMYVPVGAKNYDELKTISLTDSNSKAR
                     KATRNAIDVSNKKVITVSNKVKGNIVRDK"
     regulatory      complement(8319..8404)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(8576..9979)
                     /locus_tag="PC366_003199"
     CDS             complement(8576..9979)
                     /locus_tag="PC366_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HDF2578690.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILINSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKAKTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGF
                     TGEADAISASPVAARDGVPIILIDGNSVGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALVASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     DNGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKISDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
     gene            complement(10441..12336)
                     /locus_tag="PC366_003200"
     CDS             complement(10441..12336)
                     /locus_tag="PC366_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HDF2578691.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAEDSDNKLTATIKSTN
                     TVEVKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKSYSDIDSKELHTITVKN
                     ADLQDISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKSETISVSSKNHKLVRDLHKVLTDVKDGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRV
                     LGSNLSSKKIYIVGGESKVSKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
BASE COUNT         3520 a         2344 c         1402 g         5436 t
ORIGIN      
        1 ttaaacttaa tatagctcaa attattatac attttaacct caatattatt aaattgttaa
       61 gataatgaaa ataaaataag aatgcatcta aatatataac tttatatcta aatacattct
      121 tattttcgat ttacttaata tttatttttc aattaaactc ttaatcttat ctactacaga
      181 tgaggctatt cctccaccta cttcaaacaa ctttgatgaa tttttacctt ttaatgatga
      241 ttcttgtgat ttatctaacg tatttgtagc aagtataact ggtgaattgt ttttagctgc
      301 taatggtcca actgctaaag catctataag tttatcttga tttgcaacta caactccatc
      361 tagtttagat tgagagtaga atttatctat tactttggca ttcgtctctt gtctagtttg
      421 acctgccacc ctattgtttg atatatcttt gtttgctatt tttccaactt gttcaatagc
      481 cttgttagat attttttcta ttccaccaat aaagtatata tttgacacct tatttgattt
      541 aataaattgt acagcttcat tatctacacc atctttttgt gtaagtacta ttggagtttt
      601 ttctttaccg gccagtgatg ctattgataa tgaatctgct tctccatttc ctgcccctat
      661 atacaatttg cttacattat tcgtcttatc tatttctttt gctatattaa tagaagtttg
      721 atatcttgta tctccaccta ttctctgtac tgatattttt gaatttacag ctttgatagc
      781 ttcaacaact gaatttggca ttgagttgtt tccacctatc acaattactt ttgatggatt
      841 tagccttttc aattcttcta cagttttttg aggaagcttt tcatttgatg ataaaagaat
      901 cggtgagttt tttacactag caagtggtgt agctgtaagc ccatccacca tgcttttatc
      961 ttctccattt actattacaa ctgtatctga ttttgtccaa ccactttgag atattttggt
     1021 agctgtctca aatctatcag caccttttaa ttttttgact gtgacattag atgtagaatt
     1081 acttgaactt cctcctccag aacttccacc actagacgag ccgcctgaat tacttccacc
     1141 accattattt ccaccattgc cattatctgg tggtaattca tccggttttg ataattcatt
     1201 ttcaactatg tattctaaac tttttggaag tgtaacttca acatatttat ttattgtagc
     1261 ttttcttccc ttagttattt tttgtgctaa tccaagtttt aatattacat ttgaaccact
     1321 ttcttgtgtt tctttactaa caatagaata gtttatccta atattgttta ataaatattc
     1381 aagtgcttca cttttctcta ccttatactt ctcagggtca tttttactag aaccagttcc
     1441 accaattggt tttacttcac tctcattaat aagggtaaat attaatcctt catcagagtt
     1501 tatattttca taatccactg ttttgttgtt atatgttaca atttttaaag ctggtttatc
     1561 gcttgttcct tttcctaaaa ctttatagtc agcatttgag ttactgccag atttttttac
     1621 agatattctt cctatattca atctatttcc gtctagtaaa tcttcatttg atgtaacata
     1681 tatatctaat gtagttgtat tacttgattt gttgtattct actctacaag tagcatttgc
     1741 atttccactt tttatctgag attttatatt atcagaccaa gtaatctttt ctttctgctc
     1801 attatctact acttcaacct caccttgtac ttttatactg gcttgaaatg aatatactat
     1861 gttttctact gagtccacag atatatctat agtatttact ttctcatacg tttttgttcc
     1921 ttgtaaaact ggagctgcat atgcacatgt aacactacca gttacagcta ctgccatagt
     1981 tgatactgct atagttctta taaaagattt tcttttactc attaacaccc gtccttatct
     2041 atcattaact aagtggataa atttacttat ccacctagct tttatattta atttataaat
     2101 taccctaaac ttatagttac atttatatac tttgctttta atatctacta ttttaaaact
     2161 attctagtac ctaatcatat tagatataca atgttagtat tagtattttt acgtttttag
     2221 agttccacct actatttatc tctaacaata ttacccttta ctttattgct tacagttata
     2281 accttcttat tactgacatc aatagcattt cttgtagctt ttctagcttt actattacta
     2341 tcagtaagac ttattgtctt taactcatca taattcttag ctcctacagg tacatacatt
     2401 gtatcactta caaatctttg acctactggc gtatctcctt gaaggtcatt gtatctatat
     2461 agttcagcct taaccttatc acttaaagaa tcaaagtttt cttttggcat atagtaaacc
     2521 catgtacctt tactgatttc acctaattca cctttttctg gaacttctgc aaataaaagt
     2581 gcttctccag atatagtctt attgttttta tctataagta gtggtaaatt aaatgctgga
     2641 tttccactgt attcacctgt aataattatt gaacctgctg gaatcttacc tgtttcatct
     2701 tcacttgtgc tagggtcatc actttgatat acataatctt ctgctaactt tccaattcca
     2761 ttagtacgag tttggtctgc attattcatt gtgccaattt ctatattatc acctggaggt
     2821 cctattatat ctaattctgc aacttctata ttagacttat tgtttgagat tagttttaca
     2881 tatctagctt ggtatgtcca aagtttatca tctttattaa atgtaactct agcttcatta
     2941 tcttggtctt ttcctccacc aactaaatct tgtccatatt caaaagttcc ttgacttaca
     3001 tcttcccagt tctttttatc attacttact tgtatcttgt aattagttaa aggattgtat
     3061 gttgtgctag tattctttct aaagttaaat aatcctttta atgagaactt cctagtttct
     3121 gcctctggtt ttgtatattt tagtcctact ataggtaatg tttctttcat gtctactatt
     3181 atatatggat tttcttctac atttatatca gggtcttttt gagggtcttt gttccactct
     3241 gctttactta ttatctttcc tttatatgta gtacttacat cattatcttt tatattatca
     3301 atttcaggat tttgtaatgg tccatgtgag tcattttcag ttctaacatc accgtcagaa
     3361 acagtatttg ttatgaatga ccatgctgat ttatttattt tcccttcatc tgataatttt
     3421 acagtgccaa cttcaaattc ttctgttgga tttaggtgat aatcatatgc aactacctta
     3481 tatgtaaatg ctctgttatt aagaggagat atactatcag taaatttggc cttactattt
     3541 ccttttgcat ccacaaatcc aactgttctg tattttacct gtgttccatt ttcaccatct
     3601 aaataatttc catcacttct tattatttcg tatcctagta tcttatcttt atccttatct
     3661 acatctaggt ctatagatat tttattagat ttaactagag aaccactttg tattccatca
     3721 gaaaaactag cacttacttt agtatctttt gccatactag ctatattttc atttaaaatc
     3781 tttcttctag cttcgtcatt tacatattgt atctttcttg attctttttc atagttctta
     3841 ctatccatta tactgtttaa ttctggtgta atttctactc cccatgcctt aaagtaatct
     3901 cttaaatctt tttcaacaac acttgatgcc attgctacta gcatttggtc ttttggtaaa
     3961 ctattaattg ggtcactact tgaaagtgct ctgtattttc ttgaaatctt tgcatagaat
     4021 gtatcattac ttaaatcagc atctgagtta ttctttaaca ttgaacccgt aaaatcatca
     4081 tcataagcta gatgtaattg ccataacatt ccaagccttt caaatacatt gcttggtata
     4141 cctaagctat ttgaagttac atgctcatat atcttatcca ttgttgaacc ttcaagtctt
     4201 gaatgtgtct tatcatcaaa ggtctgagca agtaaagcaa gtacattgtt actagtttcg
     4261 ctatatgtca tctttccaat atctgtaaca tgtcctattt catgacctat tccccatcca
     4321 aataagtttc ctcctgtagc ttttccacta tcatctattt ggaaaggtac tccattcata
     4381 agccctggaa ctgaaccata ttctactcct acatgtaatc cagaagcata cataaatgct
     4441 ccaataaaca ttctttggta ttttatgttc atacgagatt ttggagccat atcattttta
     4501 gttaagttaa attcattatc atctacagtt ccattaccat ctaaatcttg tgttttaaat
     4561 actcctcttt ctgagtaaac taaatccatt atttgttccc atgcaagcat actattatat
     4621 aatctatcta cttgtgtatt taaatcagca tttccttttg atattccttg atatacagct
     4681 gttgcaggaa catttaatgt tactttatca ctttcaatat ctgtagtgtt taacacacca
     4741 gttttttctg aatattcata tgaattacca atatttgttc ctggataata tggttctcct
     4801 tttacagcat ctttatattt agctaattct tctatatatg cttttatctt tttcttagat
     4861 tcagaaactc ccgcaggact cttatcattt attgttccat ttagattaag atgtggtatc
     4921 ttagtagctc ctgctacacg tacttttata tctcctccac ttggagtatc ttcagggtat
     4981 cttatgtata aacttcctcc acattctata tctaaactat gaagtttgct taattgaatt
     5041 acattttttc cagttttaag atttatttct ccactcttat atgcaccaga ttctccatag
     5101 tactgtgtat atatcaactt aggagttttt ccacttttac ttccaacata tactgttatt
     5161 tcatctcctg ctctagcagc tactcctaat gcctgccagt cattttgcat gcctaagtta
     5221 ttggaattta cagtatactg tccgttttta tctttatatt ttcctgattt atttatttct
     5281 tgatttacag tagttacatc agtaagtgtg gctctatcat tatataagtc ttgagctaat
     5341 tttaattctc tatcaataac tgtcttatat ggatgatatt ctccactagc tttatctgga
     5401 gtatttaatc tatcttttaa ttcagttatt ttttcttgag ttacatcttc ttttaattca
     5461 acttgtaggt catccataaa tagatttctt acatcatctt ctatactgtc atactcataa
     5521 aacttaagtt ctgatatatt agacttatat gaataagatg aacaaacact tacttgtatc
     5581 ttagtagcag ttattggttc ttttaatcta accattacat acttattatt atttacaggg
     5641 tctgtctttg tttcaaaagg aacatccccc agattgtgta attgaccatt ttcatcccaa
     5701 tatcgtatct caaagtcatt tattgtctta tcagaaacat caaaacgagg tgtagccata
     5761 aaagtatcca tagtataaga tttatcaaaa gttattattg gtcctctatt cgttccctca
     5821 gctgcattat atgttgggaa tgtccaatgt gttgtgaagt ctccatctac tacattgaat
     5881 ttatcaaatg gatttttatc actatattca cttttgtcat atcctgctgg ataaacaaca
     5941 tctacaatgt gatttgttgg tattccaaat ccaccattct ccttaggagt attaattaat
     6001 ctatagttag gtgttgttgg tgcatctatg ctttcagttg tacctatata tgttttagac
     6061 attccactag ttcccaagtg gttagtagct gtcattctaa cttcatatgt tgtgttatcc
     6121 ttaagacctt ctatttttaa acttgtccca cgaataagct tatcattgta ttttatccaa
     6181 gacccattag agcctttttc tttatagtac aagtcaaagt ctttagcttg tttatgattt
     6241 ttccagctta catcaagaga tttaaattta cctttaacat ttataccttc tggtggttct
     6301 ggttttgtgt ctggaacaac ttgaaattct aatatgctat ctgggctaaa ttgtataggt
     6361 ttatagtttg agtctacatt ttctggtact ccatctaagt tttctggcgt tgcatcttta
     6421 taaccactag accaatctcc atttaaagat tgtatgctaa ccctatatag tccatatgct
     6481 tctatatctc taacttctat tgtattttta ctagtttgta attttttagt agataatact
     6541 tttcccttac tatcaatttt atctagtata agttcgtatg ctgatacatt tacttcatta
     6601 ttccaataaa aagatacttt ttcatttcca acagcagtgc tagtcgatat tttatttatt
     6661 ttaggtatgt tcatctctgg ctttggtatt tctttatata cattgtttaa aaattcaact
     6721 tttgatattt ctgcaagatt tctatcgttt gctgttgtag ctgttatttt tatagttatc
     6781 ttttttactg ctacttgttt accaagattt attactatat cgctattttg aacatctgta
     6841 tatgtttcta atgctgccct actatatgta gatgttgtag agttatcatc tttactgata
     6901 ttatcccctt cttttggagt atcttcatct gaattaggtt tatccattga tgaattttct
     6961 ttatcattat ttttatcttg attggtatta gagtttactt cttgtttatc gctattttcc
     7021 tgttgtttat cattattttc atctttatta tttgaattat tatcagtctg atttttattt
     7081 tcatctttat tatttacttc ttcttgattt acttcttctt gttcgttatt tacttcctct
     7141 tgttgctcct tatcttttaa gtttttcata tattctttat tttcataagg aatctgttga
     7201 acattaccat cttcgtcagt aacctcaact attccttttg ctggagcagt accttctgga
     7261 gcttttatat tgatgacttc catattaagt gcttctgata aagctatatc cattactgct
     7321 ggtttttcct cagatatttc atcatttttt gaagatattg taactccatt attttctcca
     7381 ctaaataaat tttctacatt accattaata tctacatcac tatttccttt taattcaacc
     7441 ttacttgtat ctactatagg attggtagat actatacttt ctaggctttt tgcatcttca
     7501 ctttgtccta aatttttctg tacataatct aagtcaacaa tatctacctt tccatctcta
     7561 tttaaatcaa attctctttt atttgaatct atattctcta aaaccttatt ataatcactc
     7621 ttatctactt taccgtctcc atttacatca cccattaaga ataattcata atttaaaggt
     7681 ttatttttat tatctacact tgctctattg cttaataaga ctctttgtga ataacttgat
     7741 atatcaatgt ctttaatttc tttgttctta aatccagctc cagagacttc tatattgtat
     7801 tttccaacag gtaaattatt aaatacaata ttataatatg atacattctc atctttattt
     7861 tttatttcac ttctacttgc agataatttt tttatagtat attctatatt atctgtccca
     7921 atatttactg ttcctgaatc tttttctcca agctttatta ttccactatt gttactatca
     7981 tcttttaatc gtaactgcat attagtcata ctttctgact cgctattttt tattggcagt
     8041 gaaaaattta aatctacttc aagattcccc cttaactttt ctgtaactga tttttcaact
     8101 gcccttagct tcccctctaa tataggttct gcaaaaacat ttagtggtgc actacacata
     8161 gatactgcta gtacacaaga tattgccttt ttcatgaaac aacaatcctc ccttaataaa
     8221 tctctaattt ttcatgaatt taaatactat aagtttcaga caataaaaaa agacactcaa
     8281 agagaatctt aattataaaa taaaaagact ttactctttt tagcaactgg ctgatatggc
     8341 tttaaaagct ttaatcccta tagttttgcg tcattagatt tccctaattt tgccatttaa
     8401 ttttcactac tttcttaccc attttatact atatttaaac tttttaatac aattttttta
     8461 cattaaatta taaaaaaata acatttatat taataaatta atataaatgt tattttccat
     8521 tataatttaa ttatttatat agcttcctta caagcataat tttgtgtata ttttcttatt
     8581 ctttatatct tccataaaat tcatgtgtag catatagatt cttatctcct gttatagcta
     8641 taccaaatcc cattatttca taccctttat gcaacatatt agttccttct tctggatttg
     8701 tcttccactc attaaaaata aagtttccta tatcatctgc atctctattt gtatatacag
     8761 gtttatctga aattttatat ttaattatat tttcaccttg aactgctata tatccaggtt
     8821 taatctcact ccaatctaag tatttcaaaa aagtagaata tgaatttttt ccatttatcg
     8881 tatgagataa agtcttctta tttgccatta aattagacca atcatttgct agaccctcta
     8941 atctgcttgc tacagataac gctcttactc cattatcttt tctatactgc tttgtaagag
     9001 catatacttt accctttatt ctctctttaa atgctctatc atttggattg taatataacc
     9061 cttgttgatt tggtgaagct tgatttatac attgcttgat aacattctga tttatgcctc
     9121 ctagtacagt caatttgtct gcaccactta aaatactctt gttactgcca ttttcaacta
     9181 aaactacagg agcatttttt gctattgtag aggcgaccaa agcgtctgtt aattgcaagc
     9241 ctttacttag ataaaattct ttactatttt tataaaactc ttgtataact atcttattag
     9301 tttcaaatct atctgtgcca cccaatctaa tagaatttgt gctcttaact aattcgtcgc
     9361 tgattatttc actagaacca agcgcataac tctttaagcc tgtcgtgtca aatcccacac
     9421 tatttccatc tataagtatt ataggtactc catctctagc agctactggt gatgcactta
     9481 tcgcatctgc ttctcctgta aatccattgg ctataattac tttatctatt ggcttaattt
     9541 ctttgatttt ttcagctatt tttatacttg tatcaaatct attttcacca aatattcttt
     9601 gtacaacctt ctttttggat aataactgat tctcaacatt tttacttatt gttgattctg
     9661 agcctattat atacacagtc tttgctttgt ttaatctttc catagttgtg tttggaatct
     9721 gattttgctt tgtcattaaa ataggcgcat ttaaggctcc agctaaacca cttgcactta
     9781 gaccatctgc taagctatta tctgagttga ttagtattgc tgtattgtag ttttgcttat
     9841 ctgctatttt tgctgctgtc tcatatctgt cattcccttt tatttgctca actgatgtca
     9901 acgcatttac cataggagta tttaccatta ctaaaaatag tgtaagtcct atagctaata
     9961 tctttttact attcttcata ttattttcta cccccaatgt acttttcata ttttttatta
    10021 gtactcatac ttatttttaa tcaaaagtta caattttgtt accatatttt atatatgata
    10081 ccatagttat ccatacaact caaacaatat acctaaagtt tttattctct ataaattcaa
    10141 aacattataa tttattttat ttaattaagt tataagttca aaataattta tgttagtaat
    10201 atgtttaatc attataagaa gtatcttttt ataataattt ttgcaatatg aatttctcca
    10261 cattataatc aaaaaataaa ataaggtatc tcaatctaat tctaaatgag acaccttatt
    10321 tttattattt tatcttgtta tttgtatatt ttataatatc tacactatgt cttacatatt
    10381 aacgcattgt ataatcatat attatctaaa taaactttta atattaattc ctatatctta
    10441 ttagttctta gtaaataagt ttattttttc tgctattttt tcaatagcgt ttttagctat
    10501 tccttcacct atttgtacta acttagtagc attcttaagt cttaactcaa ctacttcttc
    10561 ttgtgattta gaaagttctt ctgtagttaa tactattgga gcctttgaac tagctgcaag
    10621 tggtgctgct gtaagtgcat caactaattg tccatttcca cctacataac catcttttgc
    10681 tacatatgct ttagttgcac ctgcatagta tttattgatt actttagcat tagtatcttt
    10741 tctattttct ccagctaatc tttcaacttt attatttaaa tctatatcaa ctaatttgtc
    10801 ttcaacttct tttgatacag aattttctcc acccactatt tctaattctt ttccttttaa
    10861 taatttttca gcatttgcat ctaattcgtt acctgtaact attattggag caccaaattg
    10921 agcagctcta gctgatatac tcatagcatc agcttctcca tttccaccta ctacaaaagc
    10981 agtcttaaat gtatctttta attgttttgc tatttctaaa gaagtttcaa atctatcttc
    11041 tccagaaact ctctcaactt tacttacacc taatttagaa agtttttctt cagtttcttt
    11101 tgatacttta gattctccac ctactatata tattttctta gaagatagat tacttccaag
    11161 tactcttaat atttcagctt ctatttctga tggtagtgaa tcttttttag ataataatat
    11221 tggtgcattt ttttgagagg caagtggtgc tgatgctaat ccatcaacta tagcatcttc
    11281 tccaactaaa attatagctt ctgcttctcc atctttgaat ctctctttac taacttctac
    11341 tgctgttgta aatcttgaat caccagataa aacctctact tttaattctt ttccatcttt
    11401 tacatcagtt aatactttgt gtaagtctct aactaactta tggtttttac ttgaaacact
    11461 tattgtttct gacttttcat ttgccttgct taaaactata tcaaagcttg atttttctgg
    11521 tttatcttta tcatcactat cttcttgttc ttgagtaagg attgcttcat tttcaaatgt
    11581 taaagcatat ccatttttaa ctttattaac tatttctctt cctaatgtag ttaatctaat
    11641 tccatcaaat aattcttctg ctgatatgtc ttgtaaatct gcgtttttaa ctgttatcgt
    11701 atgtaattct tttgaatcta tgtcactata actcttttca taaccttcaa aagtaccttc
    11761 ttctgatgtt atcacttttg agaaatctaa atgttggtct cctacattta atgtaataac
    11821 atttgctgaa tcttttgctc tttttacttc aactgtattt gtagatttta tagttgctgt
    11881 taacttgtta tcagaatctt ctgctaaagt tgcattgtaa gcattaactg catctactat
    11941 ttcttgagca gttttgtagt tttcaatttt atagtcaact acttttccac ctaacacttg
    12001 atgtccttta tcttgaatag taacttttaa actttgccct tctgttaaag agtttatttt
    12061 attttgtaat tgagttgcat tagttaagtt tacattgtct acttttatat cgtaaactct
    12121 atcatttaca tttgctcctg cttttgtatc ttcaaactta acttctaatg cttttctaac
    12181 ctcttcgatt agtttagcag aatctttcgc acttactgtg taatttttat caacattttc
    12241 tgtcacagta ttgtctgcga atattggtgc tgctgcactc ataactgtag cacctgccat
    12301 tactattgcc atacttctct ttttgttgct taacatattt atgtcctccg aatattattt
    12361 tttatttttt atattcgtat ttcccacaca taaataatat tatatataat attatttttc
    12421 aatatatttt atgtgtttac ataatttact aacacaaaca ctaataatat cttcttgaac
    12481 cccttccccc tacttagctc tctataatta tgctcaaaga tagaaatccc tattttatag
    12541 tgattttcta ctaaacaatc atatactaac aaaagtattc aaactccatt tttatatact
    12601 actatgcact aatttttgct ttgctcttat tacttaaata tatatcacta aattaatatc
    12661 tacctccata tattaaaata tataacatat tataaaatca tc
//
LOCUS       DAMJWO010000100        12133 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.103, whole genome shotgun sequence.
ACCESSION   DAMJWO010000100 DAMJWO010000000
VERSION     DAMJWO010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12133
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.103"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(172..2283)
                     /locus_tag="PC366_003201"
     CDS             complement(172..2283)
                     /locus_tag="PC366_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2578692.1"
                     /translation="MTINKLYSKLRAYNWKNYTTLFFCIILSVVLVTSYALIYFSPTI
                     QNILPTGGDSRKQATMIFSVAILGCAVFTTYASSLFLKFKSKEIGIFMALGTDKKKLK
                     KLLFSEILLISIVCCFLGLILSIPVSFGIWKIFQLVIIDTREMTYHFGTQGFIYGFIF
                     SVFVTLCIFILSVKFINRTNIIDILNDQRISEPIQDVKDWYGILGIIFIILGIFLGYI
                     VPSLTINKLNYRLPSVWSFTYLLSLIGIYMIMTYIVVHAKRGKHPEKYYKNIISTSMM
                     RFMGRQTVKNMCVISFLIAGALFAVFYVPNMVAGIYDTLKNNPIDYTFTYNQRDKQVS
                     KKDIEQLADKHNIKIQNYMEIPSIELIVDGVESIYHKDGTIERVYMKKSSYDMFFNSK
                     DFSKLIDKPITIKNGEYLAVVNKGNENQDYKYTKFISSPVTEKEIPFRYAGKIIFNGS
                     FFQNRSMNAYVLNDEDYKSFTKDLSIKNYNNSILFNVDKDTYAFANDLKKEIIKRTSK
                     EMGMFSGYDEYVKKRYESTGRKYFMDEEYPSGEGHLKLDPNNNQLYLNWKYYPNFKIL
                     QSQDMIKNMAVFLMLFIYVAIICFTAVGIIAYTRGVTIAINHKQVFMDLNRLGANNDY
                     IKFCIRNQLKKVFSYPLIAGSFLIYLFNFMIMLNNDGRIVNSEVNALLINLGFIGICG
                     VYMYLIYLLTYKKFKKIIGIL"
     gene            complement(2273..3025)
                     /locus_tag="PC366_003202"
     CDS             complement(2273..3025)
                     /locus_tag="PC366_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578693.1"
                     /translation="MLKVNQLCKSYKTGNKTYPVLKNISFEINKGEFVAIMGSSGSGK
                     TTLLNCISCFIPIDNGEIILGNNNIRNLKEKELSEVRNQQLGFVFQDFMLFDGLSVFE
                     NICVPQIIKGSQVLQMENRAINLCELFGIEHIRKKYPAEISGGEKQRTAVARALMNNP
                     DLILADEPTGNLDSKSCRTVIESFLKAKQELDATILMVTHDSFAASFCDRVIVLKDGI
                     IYKEVVKSNSRHKFLDELLEVLKEMGGAQDDN"
     gene            complement(4321..4497)
                     /locus_tag="PC366_003203"
     CDS             complement(4321..4497)
                     /locus_tag="PC366_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578694.1"
                     /translation="MFFTFIGVISAILLLCTIICGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
     gene            complement(4601..5209)
                     /locus_tag="PC366_003204"
     CDS             complement(4601..5209)
                     /locus_tag="PC366_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2578695.1"
                     /translation="MEKLLRGKIMKADSTKEQLINATIQLLSSHRDVSSITAREIVAK
                     ANVNLAMINYYFKSKEELINISIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFD
                     FIGEHSQFIKISVPYILIQEEIVYPFEILPLIKAHYENQNNKKTEAEYRTIAYQITSF
                     IQLLFLRSNAFFKYSGIDILNVEQRNGLIDFQLDLLLVDITK"
     gene            complement(5308..6132)
                     /locus_tag="PC366_003205"
     CDS             complement(5308..6132)
                     /locus_tag="PC366_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2578696.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAEIDKYTGHRLYSVE
                     QISILQRIVLLRDSKFSVAEIANIVHNWNDEFVIKELNRKKNEIQKEIKHEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISLREVVPDYQSEGILWEKLSKFIKEEHIE
                     VSRQPNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHKGEHNEINPENYLTEIQIPLIKV"
     gene            complement(6310..7203)
                     /locus_tag="PC366_003206"
     CDS             complement(6310..7203)
                     /locus_tag="PC366_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2578697.1"
                     /translation="MQLYNTPFNTNKHLIYFFTSTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEIRIKWILLTILFFALTFIT
                     SLIIGNYFNVKTSDIDWIHIAVFRPSKIAYMLLASFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFNIQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDW"
     gene            complement(7460..7897)
                     /locus_tag="PC366_003207"
     CDS             complement(7460..7897)
                     /locus_tag="PC366_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HDF2578698.1"
                     /translation="MKIHVEQGINCDDIEITIKCSALDNNIEKIISLLSTPLLDIKGK
                     KSGEIYKLNVCDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLKNNEKVIINRRYIKNIKEKLNI"
     gene            complement(8154..8303)
                     /locus_tag="PC366_003208"
     CDS             complement(8154..8303)
                     /locus_tag="PC366_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HDF2578699.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LIFKK"
     gene            complement(8316..8546)
                     /locus_tag="PC366_003209"
     CDS             complement(8316..8546)
                     /locus_tag="PC366_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HDF2578700.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIE"
     gene            complement(9238..9459)
                     /locus_tag="PC366_003210"
     CDS             complement(9238..9459)
                     /locus_tag="PC366_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HDF2578701.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVVKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            10039..10296
                     /locus_tag="PC366_003211"
     CDS             10039..10296
                     /locus_tag="PC366_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2578702.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVAKLYGGTNTYIPTYKGL
                     FRYARNRDIVKQFNGVNHNELAIRYNMCVSNIKRILNENNV"
     gene            10745..11983
                     /locus_tag="PC366_003212"
     CDS             10745..11983
                     /locus_tag="PC366_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HDF2578703.1"
                     /translation="MNKGFYKLNSVVLNFDIKNDVNKIRFNHYIMRKENIQRLQGTLP
                     NGQFYMTVRRAATDLQLSISTISRLVKEFLDLGIIRLVSKGVKGNRSVYSYVSIEFNG
                     SLFDDSKYMELDCVCNDEFIDNSGIEFDCDSKDNSFNGDINVETVHCINEYFSDDDVE
                     HNYNNFHNKDTIKDKAISNISTIKKYIDESFDTNKSENSNLQQESINFNFNDTCNEID
                     KRTNNSIENNQNKRPMRLSDISVLSDKGMTNKKNYFNHNHGIQKRNKSATKKKESLNK
                     FNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEVKVAKWK
                     NTIMEMYIRPETLFSYKFESYVNENISMKSQSNVHPCKEGNSNDSSNYIHSDYTTYDG
                     SVRERKKYENVRYWNPICEI"
BASE COUNT         4526 a         1446 c         1631 g         4530 t
ORIGIN      
        1 aatataatgg attttcatat tataaaaagc aaataattat cttactataa aaatacaatg
       61 acttttcata tcataaaaat ctaataacct tttttaattt aaaatgctaa tgcttttctt
      121 attataaaaa gtaatgattt tattacttta aaaatctaac aaccttcctt attataaaat
      181 accaataatt tttttgaatt tcttataagt taatagatat ataaggtaca tataaactcc
      241 acaaatccct ataaaaccta agtttatcaa aagagcattg acctcactat tgacgattct
      301 accatcatta tttaacataa tcataaaatt aaacagataa attaaaaaac ttcctgcaat
      361 aagagggtat gaaaatactt tctttaattg atttctaata cagaacttta tataatcatt
      421 gtttgctcct aatcgattta aatccataaa gacctgcttg tgatttatag ctatagtaac
      481 accccttgta tatgcaatga ttcctactgc tgtaaaacat atgattgcca catatatgaa
      541 taacattaag aagactgcca tgttttttat catatcttgg ctttgtaaaa ttttaaagtt
      601 aggatagtat ttccaattaa gatacaactg attgttgttt gggtctagtt ttaaatgacc
      661 ttcaccactt ggatattctt catccataaa atattttctt ccagttgatt cataacgttt
      721 ttttacgtat tcatcataac cactgaacat gcccatttcc ttagatgttc tttttataat
      781 ttctttcttt aagtcattgg caaaagcata ggtatcttta tctacattaa atagtataga
      841 attattgtaa ttttttatgg ataaatcttt agtaaatgat ttataatcct catcattaag
      901 gacataggcg ttcatacttc tattttgaaa aaaagaacca ttaaatatta tttttccagc
      961 atatctaaag gggatttctt tttctgtgac tgggcttgat ataaatttgg tatatttata
     1021 atcttgattt tcatttcctt tatttacaac agcaagatat tcaccatttt ttatagttat
     1081 tggtttgtca attagcttgg aaaaatcttt agaattaaag aacatatcat aggagctttt
     1141 tttcatatat accctttcga tagttccatc tttatgatat attgattcta caccatcaac
     1201 aattaattct atagaaggaa tttccatata gttttgaatt tttatattgt gtttatctgc
     1261 taattgttca atatcttttt ttgatacctg tttatctctt tgattgtagg taaaagtata
     1321 atctataggg ttatttttaa gagtatcata gatacctgca accatattag gaacatagaa
     1381 tacagcaaat aatgctcctg caatcaaaaa tgaaataaca cacatgtttt ttactgtttg
     1441 tcttcccata aatctcatca tgctagttga tatgatgttt ttatagtatt tttctggatg
     1501 ttttcctctt ttagcatgta caactatgta tgtcataatc atatatattc caataagaga
     1561 gagtagataa gtaaagctcc atacagatgg tagtctataa tttaatttgt ttatagttag
     1621 tgaaggtacg atatatccta gaaaaatacc tagtataata aaaattatac ctaatatacc
     1681 ataccagtcc tttacatcct gtattggttc agatattctc tggtcattta atatatcaat
     1741 tatatttgta cgattaataa attttacaga aagtataaat atgcataatg tcacaaatac
     1801 actaaatata aatccatata tgaatccttg agttccaaaa tgatatgtca tttctctggt
     1861 atcaataatc actaattgaa atattttcca tataccaaaa gatacaggaa tacttaatat
     1921 aagacctaaa aaacagcata ctattgaaat taacaatatc tctgaaaata gaagtttttt
     1981 taatttcttc ttatctgttc ctagagccat gaaaatacca atttccttgc ttttaaattt
     2041 taaaaagagg gaagaagcgt atgtagtaaa gacagcgcat cctaatatag caactgagaa
     2101 tatcattgta gcctgttttc tgctatctcc accagttgga agtatgtttt gtattgttgg
     2161 gctaaaataa attagagcat atgaagttac taataccaca gaaagtatta tacaaaagaa
     2221 taaagttgta tagttcttcc aattataggc tcgaagtttg ctgtataatt tattaattgt
     2281 catcttgagc gcctcccatt tcttttaaaa cttctagtaa ttcatctagg aatttatgtc
     2341 ttgaatttga ttttacaact tctttataaa ttattccatc tttaagcaca ataactcggt
     2401 cgcagaagct tgctgcaaag ctatcgtgtg taaccatgag tatagtagca tctaattctt
     2461 gctttgcttt taaaaatgat tcaatgactg tacgacaaga cttactatca aggttaccag
     2521 ttggttcatc tgctaatatt aaatctgggt tgttcatgag tgctcttgct actgctgtac
     2581 gctgtttttc tccaccagat atttcggcag ggtatttttt tctgatatgt tcaataccaa
     2641 atagctcgca tagattaatt gcacggtttt ccatttgtaa gacttgacta cctttgataa
     2701 tttgtggaac acatatattt tcaaagacac taagaccatc aaatagcatg aaatcttgga
     2761 atacaaatcc tagttgttgg tttctaactt ctgaaagttc cttttctttt aaatttctta
     2821 tattattatt tccaagaatt atttccccat tatcaattgg gataaaacat gaaatacaat
     2881 ttaaaagagt agtttttcca cttcctgatg aacccatgat tgcgacaaac tctcctttgt
     2941 tgatttcaaa agaaatattt tttaatacag gatatgtttt attgcctgtt ttatatgatt
     3001 tacataattg gtttacttta agcatatata tcatcctcac tttcatttat cttgtaagtc
     3061 aatgatagca tttgaaaggg gaggagggat atgagcaata ttgtaatagt tggatgtttt
     3121 tttgtaatgt ttgaaaatat attgtttgga tagtgtgaga ggttattatt atagttaaat
     3181 tgattatatt attggaggat ttagagggtt atttttaggt attaattgtt gtgctaaagt
     3241 aatatgatgt ggaacattga aggtgtagtt agaaaaaagg tatatagtaa aagtaaaaag
     3301 gttatagaat aacgaatgtt gtattgaaaa aaatgatgta aataatgtat agtagggtta
     3361 aaaagaaaaa aagaattata gagcagtaag attatttaat ggaatgtatt gtaaataatt
     3421 tgaaaggatt taggggttat taacacaatg taattgagaa aatatattgg agttttggaa
     3481 ataaataggt cgttaaaaac aattgaaatg tataataaaa aggttaaaaa gtattattag
     3541 tataggtatg atagataatt ttagaaagtg gaagtatttt agactatgct gaaaagtgat
     3601 tgatatgatt ttgagatatt aaaatattac tatattatag taaagacgtt aaaataataa
     3661 aatgttgtaa taataaaggt ttgtagtata ataaagaact gtaataaata agactttgca
     3721 atgtaataga aatgctgtaa taataaaagt ctgtagtata ataaagaact gtaataaata
     3781 agagattgta atataataga aatgttgtaa taataaaagt ctgtagtata ataaagaact
     3841 gtaataaata agactttgca atgtaataga aatgttgcaa taataaaggt ctgtagtata
     3901 gcaaagaact gtaataaata agagattgta atagaaatgc tgtaataata aaagtctgta
     3961 gtataacaaa gaactgtaat aaataagact ttataatata atagaaatgt tgcaataaca
     4021 aaacaccata ataaataaga gtttgcaata taatagaaat actgtaataa caaaacactg
     4081 caataaataa gagattgtaa tataataaaa gtctgtaata taacaaaatc ctataataaa
     4141 taagatttta caatataata aaaatcctat aataaatagg actctgtaat ataataaaat
     4201 gctgtaataa caaaacacta taataaataa gaccctgtaa tataataaaa atactataat
     4261 atagtaaaaa tcatgcaata ataaaaatct ataataataa accccagcat aacaaagaca
     4321 ttaatttctt actaaaaagg ccaccacaat taacagtgaa aaagcaattg aaagtattga
     4381 aaaagtaaag tgagaattag agtcattatt acgattatta agttttatcc ataaaccaca
     4441 tataattgta cacaacaata aaattgctga tattactcct ataaatgtaa aaaacattaa
     4501 aattcctccc ccttatttaa tgcaagtatt tttagtcaat gagaatattt tcaaacgtta
     4561 ccataaaata aaaaaatgta cataaaaaat taatatagta ttattttgta atatctacca
     4621 ataataaatc taattgaaaa tctattaaac catttctctg ttcaacatta agaatatcaa
     4681 taccactata cttgaaaaaa gcattagaac gaagaaaaag caactgaata aatgaagtta
     4741 tttgatacgc aatagttctg tattcagctt cagttttttt gttattctga ttttcatagt
     4801 gagccttaat taaaggtagt atctcaaatg gataaacaat ttcttcttgt atcaatatat
     4861 agggtacaga aatctttata aattggctat gttcacctat aaaatcaaaa aatgcaatta
     4921 gtatttccct taattgctgt ttaggtgcta aatttttagt atcatgtgta gccttatatt
     4981 catccatatg acgctttaaa aattttttaa tagaaatatt aattaactcc tctttagatt
     5041 taaaataata attaatcata gctaaattga catttgcttt agctacaatt tctctagccg
     5101 taatgcttga aacatctcta tgtgaagata gtaactggat tgtggcatta attaattgtt
     5161 cctttgttga atctgctttc ataatttttc cccttaaaag tttctccata aaaaaattaa
     5221 acatgtttaa tacacgttta gatactatca tgaaaatttt gggatgtcaa tgggtgatta
     5281 gtacttaagt atttaagtac taatcgatta gacttttata agggggattt gaatttctgt
     5341 aagataattt tcaggattta tttcattatg ctcaccctta tgaccgattt gtctatttat
     5401 acctgatatt tgataatcac tatttttatc taaccaataa cagaacgatt catatgcacc
     5461 agctatattt tcatatggac cataaaccat agtacatgcc atcatatcaa tttcttctgt
     5521 ctcacgatat ataaatccag atttgttctt tccaatcttc tttacaacca ttccaacttc
     5581 aatatctaca ccattatctt tgacttcttc atcatggtaa aaagctatat tattgttggg
     5641 ttgacgtgat acttctatat gttcttcttt aataaattta gataactttt cccagagtat
     5701 accttcagat tggtagtctg ggactacctc tctaagtgat atgattttat aacttggaat
     5761 ctttttaaag acaacattgt aatgaatttc atctttatca cagtttatag cttctataaa
     5821 tttatcaatt ttatttattc tttgttgttc gtgctttatt tccttttgta tttcattctt
     5881 ttttctattc aattctttaa ttacaaattc atcattccaa ttatgtacga tatttgctat
     5941 ttctgcaacg ctaaattttg aatctctcaa taatacaatt ctttgtaata ttgaaatctg
     6001 ttcaactgag tataatctat gacctgtata tttgtctatt tctgcaggct ttaaaatacc
     6061 aagttcatca taataacgca acatacgaat agaaatttgt gttagttttg aaacctctcc
     6121 tattttaaac atgaaaatat gacctccttt tcacttataa ttagtatata ttttgttttt
     6181 atatacttca agcgattgtg gaaatacaat tattttccag atgttgcaat aaattataga
     6241 gagtaaatta tatttaagta gtaatcgtat caaatcatag attatcttaa tttataattc
     6301 atattaaaat taccagtcta actcaaattc aaaatcatcc gactttatct gttcaatttc
     6361 agaatttacc ttctgtttaa atttattaga agaaatcata tatacaagaa atattaaacc
     6421 aaatattatt tgtacatatt gagctattac acataattta atagggtagt gtagaagtaa
     6481 ttgaatgttg aaaaaatagt acatcatatg aactaaccca gctgataaaa tgcttctact
     6541 tgtattgata tatacaaaat taattataaa gtttaaaagt acaatgtttg gtataaataa
     6601 aaaagcatca aatagggagt attgtgccaa attatatggt atttgattag gtgtaaaata
     6661 cgaccctaga taccagattc cacaaacaag ccctaaaata attgaagagc ctataaatcc
     6721 aaatctaact aataatttgt caatggcgta tcctctccat ccagcttctt gactaagtat
     6781 actcaatata aaacttgcta atagcatata agctatttta gaaggtctaa acactgctat
     6841 gtgtatccaa tctatatcag aagtttttac attaaagtaa tttccgatta ttaacgaagt
     6901 aataaaagtt aaagcaaaaa ataatattgt taatagtatc cattttattc taatttcttt
     6961 aaagcttagg tatctataaa taaaatcttg ttttgcactt tgtggataga ttgtagaaat
     7021 aaaaaataga cctacaatag ctggtgatgt atatgcaaga taaaaaatga tttctccaag
     7081 tattgtattt gtaattccga gcaacgcagg tgtaagactg aatatccagt tcaatactag
     7141 cgtagatgta aagaaataga ttaagtgttt gtttgtatta aagggggtgt tatatagttg
     7201 cattttttca ctatccttcc gttttataat gaagttttaa tttttattaa ttgtttattt
     7261 atttttatat gtattaagtt atcgtttgat gttagttatt gcctataata atatcctatt
     7321 ttttatattt tgattaatta tttttacact aaatataatt aattagtatt taatattgaa
     7381 catattatat tattattaat tattaaatag gtcaataaat ttgcaattag tgatattaat
     7441 aaattacttt agatttttat taaatgttta gcttttcttt aatatttttt atataacgac
     7501 gatttataat aactttttcg ttgtttttta aagtagcttg catgcgatta tgtgatatta
     7561 cttttatact ttttatgtag tccatattta aaatcatgga tttagatatt cgtgagaagg
     7621 atgtattagc taataatttt gataatttat atatttttaa atcaatttca aatacatcat
     7681 cttcataata agcaaatgtt ttatttccaa ctgtttcaaa gtataaaata tcacagacat
     7741 tgagtttata aatctctcct gattttttac cttttatatc aagtaatggt gtactcaata
     7801 atgaaattat tttttcaatg ttattatcta gagcagaaca ttttatggtt atttcaatat
     7861 catcacaatt aataccttgt tcgacatgta ttttcattaa tcatcacctc attttattac
     7921 tgtcattaga atagcattat atcttattga gtccaactag atgcgttcta aatttcaaat
     7981 taagcatagt gaaattcaaa aataaaatag tgaaattcaa atttgaggtg gtaaaattca
     8041 aaaaaatact atggatattt ggataaatta tccaaatatc ctagtattta gcatagaata
     8101 tgtctaatta ttttacaaat agacctattt tatgacttac atatattgtc aaattacttc
     8161 ttaaatatca aaatattttt ggataatgta tcaatactgt ttgataaagt atttaattta
     8221 ccctcaattc taaccaacaa gtacatggat agagctatag gaaaaccaac attggttatt
     8281 aacagttgta aactatcatc cataaaatta gccccctatt ctataactaa gtcataagga
     8341 gtggtatttg tttccacaac cttggcttca acaacagaag ctaggtcaaa tcctccaacc
     8401 gaaaaaatat ttttagatac tatcaaatcc atgacagatt ttatattttc ttcagttaaa
     8461 tcatcctttg gattttctat agaaaaagaa acttgtttat cctttacatt tttaaagctc
     8521 atgactaatt ttttcttaat ttccatataa ttacctccga tataataatt tatattttaa
     8581 ttgtttgctt gttaatattg gtattttaat tgtcaatatt agtgttttgc ttgttagtat
     8641 taatatttca attgtcaata ttaatgtttt acttgttagt attagtattt caattgtcaa
     8701 tattagtgtt ttgcttgtta gtattaatat ttcaattgtc aatattagtg ttttgcttgt
     8761 tagtattaat atttcaattg tcaatattag tgttttgctt gttagtatta gtatttcaat
     8821 tgtcaatatt agtgttttgc ttgttagtat tagtatttca attgtcaata ttagtgtttt
     8881 gtttgttagt atcagtgttt caattgtcaa tattagtgtt ttgtttgtta gtatcagtgt
     8941 ttcaattgtc aatattagta ttttaattgt tgactctagt tattgctgat atagaaaata
     9001 tttaatttat ttcaattaat tagattaaag tagggtagca tttaaaatag ctaacatgtt
     9061 taagttgaaa tacgtttaat atattaattt ttcaaagcat taatatatta aagttataac
     9121 caaaattgaa gttataatct gccaaatcta tagcgtatta agtgcgttat ataacttaat
     9181 cttttatata aagagttaat ttttttaatt tgtaaagcag agtacgttta aaagatacta
     9241 tttagataat gatgtactat ctaattttaa aatatctaca atagggttct cttgaagact
     9301 tgctattgct tctgcaacag cataaacatc ttcatttaat gcctctgctt ttacatttgc
     9361 aaatgattta cttttaacaa ctgccttacc cttatcatca aaaccagcat ccaattttag
     9421 ttttatacta gataaatttt ttgttgaaac aacttccata aaattacctc ctaaaaattt
     9481 aatttcaaag atttgtcgac tttctttgtt agctataata ctatcatcta agataatatc
     9541 ggagttaaac agtaatttct aaagattttt tgtgtaaatt tttataggaa aaattttact
     9601 tttctgatga tgaaaaagtt tacaagttat ttttgaagat atgttcttag tgttttgaaa
     9661 tagtatttgt atatattcat gcttagttga gatagttttg tatggatttt catatgtgta
     9721 gagttaaatg ttaggtacca aagtttatgt taaattaaat gttaaagctt atgttaaaaa
     9781 ttttattaaa tttaatctgt aaataaaaaa gttaaaagtc caatattaac attttacttt
     9841 taaaccatta aaatctttat taaagctaac aaagttataa gttatgagaa attttattaa
     9901 agttaataca aaaattaatt ttaaagctaa gaaatttttt attagattca ataaaactaa
     9961 taaatatagt ttagtcaata atgtattaaa taaaaacttt gttaagtcta taaaaatatc
    10021 ttaaaggagg tgtaacttat gaagataaaa gtggaggata taccagttca atttcatgca
    10081 atggtagaaa taatcggaat tgataagttc atagaggttg ccaagttgta tggaggaaca
    10141 aatacttata tacctacgta taaggggctt tttagatatg ctagaaatag ggatatagta
    10201 aaacaattta atggagtcaa ccataatgaa ttggctatta gatataatat gtgtgtaagc
    10261 aatattaagc gaatactcaa tgaaaataat gtttaaacat aatgaaaata gccttgttaa
    10321 atgtaagagt aaagacaaag aagatgtttt ataaagtttt tttagacaaa ttaactaaat
    10381 ttactactta ttaatttaaa tacattgtat attctataaa aaaatttgtt aaatactgga
    10441 gatatattga gaatacaaag aaaatggtcg aaaatatttg ttggctaaaa aatagataaa
    10501 atgatacaat tgcttgtata aaggggaaaa ataaataaat aaactatata aataaagaaa
    10561 tagcaattaa tatgacataa tatatttata aaattaagaa tataaataga tattttaagg
    10621 gattagttgt taaattagga aatattaaaa aaatatatat atttatattt aaactatttt
    10681 gttatttata taaaaatact tatctagtta ctagcaatta ttagtagaaa tgggggaaat
    10741 agagatgaat aagggatttt acaaattaaa ttcagtggta ttgaactttg atattaagaa
    10801 tgatgttaac aagataagat ttaatcatta tataatgaga aaagaaaaca tacaaagact
    10861 tcaaggaact ctgccaaacg gacaatttta tatgacagtg agaagagctg ctacagattt
    10921 acaactttct atttctacta taagtaggct tgtaaaagag tttttggatt tagggataat
    10981 aagattagtg tctaagggtg taaaaggtaa tcgttctgta tatagttacg taagtataga
    11041 gtttaatgga agtttatttg atgatagcaa atatatggaa cttgactgtg tatgtaatga
    11101 tgaatttatt gataatagtg gcatagagtt tgattgtgat agcaaagata attcttttaa
    11161 tggagatata aatgtagaaa ctgtgcattg cattaatgag tatttctctg atgatgatgt
    11221 agagcataat tataacaatt tccataataa agatactata aaggataaag ccatttctaa
    11281 tattagcact atcaaaaaat atattgatga atcttttgat acaaataaat cagaaaattc
    11341 taacttacaa caggagtcaa taaatttcaa ctttaatgat acatgcaatg aaatagataa
    11401 aagaacgaat aatagtatag aaaataatca aaataaaagg cctatgagat tgagtgacat
    11461 cagtgtttta agtgataaag gtatgacaaa taaaaagaat tactttaatc ataatcatgg
    11521 tatacaaaaa aggaataaat ctgcaacaaa gaaaaaagaa tccttaaata aatttaataa
    11581 aaaaaatata cagcaaagca ttataaatat gctaaataaa aaatcaggta agaattttaa
    11641 aatcgattct ccaataagca taaaacttat caatgaaagg ctaaaggagg gctatgtctt
    11701 agaagatttc tataaagtta ttgaggtaaa agtggctaag tggaaaaata ccataatgga
    11761 aatgtatata agaccagaaa ccttgtttag ctataagttt gaatcctatg taaatgaaaa
    11821 catatctatg aaaagtcaaa gtaatgttca tccatgtaaa gaaggcaata gtaatgatag
    11881 cagtaattat atacattctg attatacaac atatgatggc agtgtgcgtg agagaaaaaa
    11941 atatgagaat gtaagatact ggaatcctat atgtgaaatt taattagttt aagaatgtat
    12001 ttatgataaa taagatatta atagagaata gtgagctata gcaaatgata tatcaatagt
    12061 tggtagtaag ttatattaag caagatatta ctatcaggta gtgaattata gtgaacgata
    12121 tatcaataat tgg
//
LOCUS       DAMJWO010000101        11756 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.104, whole genome shotgun sequence.
ACCESSION   DAMJWO010000101 DAMJWO010000000
VERSION     DAMJWO010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11756
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.104"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            242..1567
                     /gene="cdeA"
                     /locus_tag="PC366_003213"
     CDS             242..1567
                     /gene="cdeA"
                     /locus_tag="PC366_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HDF2578704.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQDEANSTFSFIVLFSLIV
                     GISFTVISYFFIKEISILLGATDKLLPYCITYGKVMILCTPFYILKFIFNYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGIIYFLSNKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGITTFLFNVVALKLAGENGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFVSSLLVFIIALVFA
                     PFIVRVFVSPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNMTGLWLTVPFAEVITIFISILFIKKYKGRYKY"
     gene            complement(1662..2456)
                     /locus_tag="PC366_003214"
     CDS             complement(1662..2456)
                     /locus_tag="PC366_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2578705.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIVGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYSIELSVLLKRDMIWTSISALIDPSTSSMPLTYLNYF
                     VQICINEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMVIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(2457..3332)
                     /locus_tag="PC366_003215"
     CDS             complement(2457..3332)
                     /locus_tag="PC366_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578706.1"
                     /translation="MRSSIKIENLSHSFKKQNIFNNMSLNFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSPDFKVGQIFEFSSS
                     FYKSYDKGLEEELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHVIILNEGKIIIDEEIDVIK
                     QKAHYITGNKEELEKLECIKNIKPKKAFGNAVAYFYYGDFSENDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(3336..3704)
                     /locus_tag="PC366_003216"
     CDS             complement(3336..3704)
                     /locus_tag="PC366_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2578707.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFVKNLLQEA
                     NKLEINREELVDIIINFKED"
     gene            complement(3887..4546)
                     /gene="deoC"
                     /locus_tag="PC366_003217"
     CDS             complement(3887..4546)
                     /gene="deoC"
                     /locus_tag="PC366_003217"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDF2578708.1"
                     /translation="MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYV
                     KRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDY
                     DNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
                     ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTD
                     Y"
     gene            complement(4582..6126)
                     /gene="murJ"
                     /locus_tag="PC366_003218"
     CDS             complement(4582..6126)
                     /gene="murJ"
                     /locus_tag="PC366_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HDF2578709.1"
                     /translation="MSKVAKATFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDISSKQGEKQALKFLNNVLNIIVGICIVVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTKILITGIIFIGITSVMSAFLQIKENFIVVGF
                     GSIPYNIVIIISIMLSTVFGPYILPIGAVVAMVVQLLFYMFFVKKTNYKYLYYLNFKD
                     DSLIKLLALLSPVFIGVAVNQVNSLVDTTLASTLVKGSIPALTYSDRLNGFVTGTFTA
                     SIVSVMYPMLSKLSAENNQKKFTSSVKSSINMIIISMIPISVASIFFATPVVRIIFER
                     GAFDARATQMTATALIFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIISVGVNIVL
                     DLVLIKPMAHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIKATLKSVVASLIM
                     GVLSYFTYKFIFGILGVGTFNEFVSLAISVIVGGGIYTLLMTIFKVEEVDMILNIAKR
                     KLHLKK"
     gene            complement(6600..7484)
                     /locus_tag="PC366_003219"
     CDS             complement(6600..7484)
                     /locus_tag="PC366_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDF2578710.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVIHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGKVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(7775..8251)
                     /locus_tag="PC366_003220"
     CDS             complement(7775..8251)
                     /locus_tag="PC366_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HDF2578711.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGVLDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQAKDLEEHHHHDKNCGCGCNHHHEN"
     gene            8518..9693
                     /locus_tag="PC366_003221"
     CDS             8518..9693
                     /locus_tag="PC366_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HDF2578712.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQNYDYNSMKNTLDNVSDNVNEQLKKLGESVKGSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     NDSDTNSSKNDTSSNNENNDSSQTNENNTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(9774..10577)
                     /gene="proC"
                     /locus_tag="PC366_003222"
     CDS             complement(9774..10577)
                     /gene="proC"
                     /locus_tag="PC366_003222"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDF2578713.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQGTLDRI
                     DANFGINTTKDSKEVTRTSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIIGEDKKIVRTMPNTPALVNEAMSSLSINKNINNEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(10617..11201)
                     /locus_tag="PC366_003223"
     CDS             complement(10617..11201)
                     /locus_tag="PC366_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2578714.1"
                     /translation="MNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLTSV
                     ATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLKEK
                     TMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYNSE
                     KNNHNWVNYTNKVVKILVVSIPNPFEKSDAVKEA"
BASE COUNT         3936 a         1899 c         1298 g         4623 t
ORIGIN      
        1 ttataaagct taagattata tacatatatt tctaaaaatt ttcttaagaa acagttattc
       61 cttactaatg caatatacct atttttacta atataagttt attaattagc attatactaa
      121 tttatcttaa tatgattttt tgttgatttt aagctgttta tcgtataaat aaaatttttc
      181 ttgacatata gttactatat agcttattat agatagagag taataaaagg aggtaaaatt
      241 tatggaaaat ttatttacaa gaaaattcac tacttttgaa tttctaaaat ttgtttctcc
      301 tgcaattata tccatgatat ttatatcttt gtacacaata atagatggca tctttgtatc
      361 aacattagtt ggttccgatg ctcttgctag tataaatatt gtactaccta taattaacct
      421 tgtttgtgga tttggaataa tgatggcaac gggtggaggt gctatcgttt ctatacgtat
      481 gggtgaaaat agacaggatg aagccaactc tacattttct tttatagttt tgttttcatt
      541 gattgttggg atttcattca cagtaatctc atatttcttt atcaaagaaa tatctatttt
      601 gcttggtgca acagataagt tattaccata ttgtataact tatggtaaag ttatgatttt
      661 atgtacacca ttttatattt taaaatttat atttaactac tttgcaagaa ctgatggaaa
      721 ttctaaattt agtttatttc tatcagtcat tggtggtgta acaaatataa tattggatta
      781 tgtatttatt aaatattttg gaatgggtct tttaggagct gcagttgcaa ctgctatagg
      841 tattatttta acttgtgttt taggtattat ttacttctta tctaataaat ctacactcaa
      901 attaagaaaa ccaaaaaccg attttagact tataagagat actatgataa acggttcttc
      961 tgaaatggtt acagaattat ctacaggaat tacaacattc ttatttaatg tagtagcttt
     1021 aaaattagca ggagaaaatg gacttgctgc tcttactata gtattgtatg ctcatttttt
     1081 aatgacatca gtctatctag gattcgctgc tggagtgtct ccattaataa gctataattt
     1141 tggtgctgaa aacagtgata aattaaaaga aacatttaaa cattctctaa aatttatatt
     1201 tgtttcttct cttttagtgt ttattattgc tttagtattt gcaccattta ttgttagggt
     1261 ttttgtaagt ccagataaca cagtatttaa actagcctta caaggattaa aaatatttgc
     1321 atttgctttt ttgtttgttg gtataaatat atttgcatca ggatttttta cagcatttca
     1381 caatggaaaa atttcagcta ttatatcttt tagtcgtgcc tttgttttta taatcatagg
     1441 aatcataatt cttcctccta tgttaaacat gactggatta tggcttacag ttccatttgc
     1501 tgaggttata accatattta tatctattct atttataaaa aaatataaag gtagatataa
     1561 gtattaaaaa ttaatgctta aaatcaacat ttattaaaac taataaacct gctttaaaat
     1621 acaaatttac aaatttgatt tttaagcagg ttttatttta gttataataa gtcatttgca
     1681 tactctttaa ttggtgcttt tctaagtaat aaaattataa atattatgca aataactata
     1741 attcctacct ttgttccaaa taaaataaaa ggattctgaa atgaataaat aattttttct
     1801 aaatacaata gcattttatg catattttta gttgcaaaat taactatata aattaccatt
     1861 aatatcggta atcctatcaa tatagtaata ctagtaactt ttctaactct atatgtaaaa
     1921 gctccaagta atactcctat aaaacctata catatttcat ttatacatat ttgtacaaaa
     1981 taatttaaat aagttagtgg catacttgat gttgaaggat ctatcagtgc tgatatagat
     2041 gtccaaatca tatctctctt tagtaaaact gatagttcta tactgtaacc tgttataatt
     2101 tctataaata acttcgataa aaaaatcaaa actataccta aaatagaaat cacaaagctt
     2161 aaaataatta aatctatgac aatagctttt atacaacttt ttcgatctgc tcttatactt
     2221 aaagctcctg aaaagtcttt atttgctata tttactccat acacaaatag cagtatagtt
     2281 atatatgtta aaataggatt cacaatcgtg gataaattag ttttagatgc ttctccaaaa
     2341 atcttgagga taaacactgg caaaatattc ataacaattc ccacaatcat aaatataatt
     2401 atatacaatt tagtattttt attaaaaaat tttatatatg gctttaattc attcaattac
     2461 aattcctcct tcttagtcat gttaacaaac atatcttgta gccctatgta tcctacatca
     2521 atatttgaat ttttaagtat tttttcatca ttttcactaa aatcaccata gtaaaaataa
     2581 gcaactgcat ttccaaatgc ctttttaggt tttatatttt ttatacattc taatttttct
     2641 aactcttctt tatttccagt aatataatga gctttttgtt ttatgacatc aatttcttca
     2701 tctataataa tttttccctc atttaatatt attacatgct ccagtaaatc atctatttca
     2761 tcaatcaaat gagttgatat tattattgtc cttggatttt ttatataact atctaaaatt
     2821 atgttataaa actcttgtct atttactgca tccaaaccaa ttgttggctc atcaaatatg
     2881 gtgatagctg aattagaaca aatacctatt atatttgaaa gtatagtttt catacctctt
     2941 gacagttgtt tatacttttt tttagtattt aaatcaaaat atttgcataa ttcttcttct
     3001 aagcctttat cataactttt ataaaaacta gaagaaaatt caaatatctg acctacttta
     3061 aaatctggac tataaaattc tttttccctg acgatacaaa cttcttccaa aacttttata
     3121 tcttcttttg ggttctttcc taatatttct atctcacctt cattttgaat taactgattt
     3181 accattatat ttaataatgt tgtttttcca gctccattct tacctaataa accatatatc
     3241 ttattttttt caaagtttag agacatatta ttaaaaatat tttgcttctt aaaactgtga
     3301 gataaatttt ctatcttaat agaactcctc atatattaat cctccttgaa attaattata
     3361 atatcaacca attcttctct atttatttct aatttgttag cttcttgaag taggtttttt
     3421 acaaaattat gtttaaaatt ttcttttcta gcttctttta taatagtttt tgcaccatct
     3481 gatacaaaca tccctatccc cctcttctta tataaaatat ttttatcaac caatatattt
     3541 atacctttta atactgtagc tggattaatt ttataaagct ttgaaagctc tgttgttgat
     3601 ggaacctgtt cttcttcttt tattccattt gatagtatct catcttcaat tgctcgtgct
     3661 atctgaataa atataggttc ttcattattt aatactaatt tcataggttc ctcctttctc
     3721 cattagttag ttactcaact aattaactat ataacttata atatcttgaa aaatattttc
     3781 tgtcaatact aaataaaaaa cagagggaaa attccctctg ttttttgttc tttatattta
     3841 taattaaatt ttgatttttg taatcctatc ccataagtta aaaactttaa taatctgttg
     3901 tatcttcatt ttttaatatt ttacatattg agctagttcc taacctttct gctcctgcct
     3961 ctataaattt ttctgcatca gaaattgatt taactccccc tgcagctttt atttttacat
     4021 tttttccaac atgctctttc ataagcttta tgtcttctaa agtagctcca cctgttccca
     4081 ttccagtaga tgtttttata aaatctgaac ctgacattgt tactatttca cacattttta
     4141 ttttttcatc ttcatctaaa taacatgtct ctataatgac ttttaatact ttatctccta
     4201 tagctttttt tatttctttt atttcttttc ctatattatc ataatcttta ttttttatat
     4261 ctgaaatgtt tacaaccata tcaacttcat ctgctccatt ttcaatagca tcttttgctt
     4321 caaatacttt tgtagcagta gtttgatatc ccaaagggaa ccctatcact gtacatatct
     4381 ttattttacc ttttagatat tctgatgctc ttttcacata tgatggtggt atgcaaactg
     4441 atgctacact catatctaca gcttcatcac ataaaatttt aatatcttcc catgtagttg
     4501 tagcttttaa aatagtatgg tctactgttt ttaatatatg tttcataaaa tcctcctaaa
     4561 tttataatta atataattag attacttttt taaatgcaat tttctctttg caatattcag
     4621 tatcatatca acctcttcaa ctttaaaaat agtcattagt agtgtataaa ttccacctcc
     4681 aactataact gaaatagcta gtgatacaaa ctcattaaat gttcctactc ccaaaattcc
     4741 aaatataaat ttatacgtaa agtatgataa aacacccata attaaagatg caactaccga
     4801 tttcaaagtt gcttttatta ttttatcttg tccaaaatat ccaacttttc tctttaggtt
     4861 caagaagagt aacaatatac atgcaattga tgatgaacta gttgcaagag caagaccacc
     4921 atgagccatt ggttttatta aaactaagtc caatactata tttaccccta cagatataat
     4981 cccatttacc ataggtgttt ttgtgtcttg taatgaataa aaaacctttc ccaaaatatc
     5041 tcttaatcca aatgcagtca taccaactgc ataaaaaatt aaggcagttg ctgtcatttg
     5101 ggttgccctc gcatcaaaag cacctctttc aaaaatgatt ctaacaacag gagttgcaaa
     5161 aaaaatagaa gcaactgaaa taggaatcat agaaattatt atcatattta tactagattt
     5221 aactgaacta gtaaacttct tttgattatt ttctgcactt aacttagata acataggata
     5281 cataacagat actattgaag ctgtaaatgt ccctgtaaca aaaccattta atctatctga
     5341 ataagtaagt gctggaatgc ttcctttaac taatgttgag gctaaagttg tatctaccaa
     5401 tgagttcact tgattaacag caacacctat aaatactggt gaaagtaatg ctagtaattt
     5461 aataaggcta tcatctttaa agtttaagta gtataagtat ttgtagttcg tttttttaac
     5521 aaaaaacatg taaaagagca gttgaactac catagcaacc acagcaccaa ttggaagtat
     5581 gtatggtcca aatacggtac ttaacattat tgaaataatt attactatat tatagggtat
     5641 actcccaaat ccaactacaa taaagttctc tttaatttgc agaaatgctg acataacact
     5701 cgtaatacct atgaatatta ttcctgttat caatatttta gtaaatttta cggtaagtaa
     5761 aaacctctct ccttcaaatc ctatagcaaa tatacttaca agttgctttg agaaaataac
     5821 tcctaatata gctacaacta tgcatatacc aactattata tttaaaacat tgtttaaaaa
     5881 ctttagtgct tgcttttcac cttgtttact acttatatct tgatacattg gaataaaagt
     5941 agtaactata gcagtaccta ttgctgcaaa tataatattt ggtatattca tagctgttaa
     6001 ataactctct gtatataagc ctgtaccata aattgatgat aatactaatt ctctacccat
     6061 tccaagaatc ttagagatta tagtaactat catcaaataa aaagttgctt tagctacctt
     6121 gctcatttta tcactccact tctaacatac ctctttttaa tcaagtaaaa tttggctcat
     6181 tagatataat tctatcaact aatttgcctt gcttagccct atcaaaatat aattaacacc
     6241 tatttcttaa tatatcacaa actacattat tcttcatatt tttttatttc tccaataagt
     6301 tttacatctt tcctatataa attgtatagc ttcaattata ttcaaagaaa tggagttgct
     6361 acccgataac tttaaaagta aaaaacagat tttattatct ttttaaacta tattctaaca
     6421 tattttgtcc atattgagaa attttactaa actattatgt actttattaa ataaataaaa
     6481 taacagcaca cctataaaat acaagtgtgc tgttcataaa cagattttat aaaaaaataa
     6541 ttcctaagta gagattaaca tgctttctca tactctcata tataatgtgt ctaaaaatat
     6601 taataaaaat gctttaattg ttttaactta cttggatgtc ttaattttct tattgcttta
     6661 gcttctatct gtcttattcg ttctctggta actccaaata cctttccaat ctgttctagt
     6721 gttttagggt catcatcatc aattccaaat ctcattctta aaacttgctg ttcttgctca
     6781 ccaagacctg taagtagttc ttctatcttt tcttttaaat tatgctgttc aacttcgtgt
     6841 attacaacat ctttaaaatc agcatctgat ggtataaatt caactaaact actatcctca
     6901 tcttctttta atggagtatc caaagataca acatttttat ctcttcttaa taattccaac
     6961 actttgtcaa cttctaagcc acatgcatct gcaatctcat ctatagttgg ctctcttaat
     7021 aatacattta aaagttcttg tttctttttc tttacaaaat ttattctctg atgaagatgt
     7081 ataggtatcc taatagtatt ttcgcaatcg tcgatatatc ttgttatact ttgttttatc
     7141 caccaagttg cataagtgct aaatttgtat ccttttttat aatcgtactt ttctacagct
     7201 tttataagtc ctatatttcc tgcttgaatt aaatccaaca tatcaatact atctctttta
     7261 tatctctttg ctatgctcac taccaaccta taatttgaat ttataaattt ttcttttgct
     7321 actgaagatg agttgattat ttccttagcc agctctacct cttctcctgc tgacaacatt
     7381 ttgtattcct ctatttcctt taaatacatt ttcatcgcat ttgatacatt tgatgaaccc
     7441 acacaaatat aattttcata attattttct tttttagtat ccataatcaa accccttcta
     7501 ttcatagaat ttgctaaaac aaaaataaat aatttaaacc tacataatct acaattacat
     7561 aatatcccat tctttaaatg aattgttttg tatattatgt atacaaattt ataaaaacta
     7621 tacctataat attattctac ttctaaccgc aatatcctcc ttatatatat aatttatttt
     7681 attatatgtt gttatattct tagttttttg aatgatatat gtctaaaaaa agactgttta
     7741 ctaaacagtc tttttttata tatatgctca atatttaatt ttcatgatga tgattacatc
     7801 cacatccaca atttttatca tggtgatgat gttcttctaa atcttttgcc tgttgttcca
     7861 tttcatgaaa ctcttttacc attatatcat aagttggaag agctgcctca gtatcgtatt
     7921 cttcccctct ccaatcagcg tacatcatag catccccatt agttaaaacc aatctacctg
     7981 acatagttat attatccact tcttctaaaa attctatttg tttttgtaaa acttctcctt
     8041 ctaactctac atcttcatct aaacattgca ctatcattac aggtgcataa taatcttctt
     8101 catctttaac atttacaaca atatctaaaa ctccttctgc accttcttca aattctgcca
     8161 actcaacatt tgtatcaatc atatcttgag ggactaataa atcttctatt aaatatttta
     8221 ttactctatc ttttactaat tcttttgaca tttatttttc tccttccgat tctataacat
     8281 tatcataatc atttctatat tatagtatac tacattaatt gttttttcaa tctcttacaa
     8341 aaattatttt tttattatct tccttatatt ccctttttta ttacaaagtt gtaatcgcat
     8401 tgatttaaaa aatagtttat atttagtata atagaaatgt agcacatatt tttattcaat
     8461 atattaataa aaaaatagat tgaaaatgta atgtatgtta aatctaggag gaatattatg
     8521 aagtttaaaa aacaaattag ttctattgtt gtgtctacta tgcttgtact tgggagtatg
     8581 aacctttctt atgcagatgg tacaaatgta gttacacttg gagctaactt atcagagtct
     8641 caaaagcagc aaatgcttaa ttactttgga gtaaaaaaag accaagtctt agttttagat
     8701 gtaacaaatg cagaagaaag acagtattta caaggtgttg caacagaggg tcaacttgga
     8761 aaagttacta tctcttgctc atacgttgaa cctactaaaa aaggaaatgg aattaatgtt
     8821 aaaacagcaa acttaacttg ggtaactagt tcaatgattg cttcaaccct tacaacagct
     8881 ggtcttgaag atgcaaatgt tattgctgct gctccatatc ctgtaagtgg tactggagca
     8941 ttgacaggaa tcatgaaagc atttgaggat gcttcaggaa agaaacttga tgaaactaag
     9001 aaagaaattg cttctgaaga attggtagtt acaggtgact taggagatga tatagggcaa
     9061 gaaaaagcaa caggtgtaat gaatgatata aaaacagaaa ttgtaaagaa tggtacaaaa
     9121 gataccaatc aaatagcaaa tacaataaat aatgttgtaa ataattacaa tattactatt
     9181 acaccagaac aaaaagaaca aattaaaggt gtaatgaaaa aaatagctga ccaaaattat
     9241 gattacaata gcatgaaaaa tacactagat aatgtatcag ataatgtaaa tgaacaatta
     9301 aagaaattag gtgaaagtgt taagggttct ggtatactag atactattgg tggatggttt
     9361 agtggaatag gagactggtt ctctggttta ttctcaggcg gagataaaaa agatttggga
     9421 atcttaaata acactaatga tgagtctctt ggctctgatg ctgtaataaa ttctacagaa
     9481 ggtgttcaaa taaatccaca aaataatact aattctaaca atgatagtga tacaaatagc
     9541 tcaaaaaatg atacttcaag taataatgaa aataacgata gttctcaaac aaatgaaaac
     9601 aacacaacaa ataattcaga aaatcaatca aataataatg actcagttgg tttctttgaa
     9661 aaaataaaaa attggctttc aggcttattt tagaaattaa acaaataaaa agaattgcct
     9721 aaaatggaaa ttttctataa aaggcaattc tctttattta caataaattt ttattactca
     9781 ctcatttttt tagatttttc tatacatgca catattgctt ttatcacaga agctctaaaa
     9841 ccttcttctt caagtacttt aactgcttct atagtagttc caccaggtga acataccata
     9901 tcttttaatt caccaggatg ttttcctgtc tcaagtacca tttttgcaga acccataaca
     9961 gcctgtgatg caaacttata tgcttgtggt cttggcattc ctgcaattac tgctgcatct
    10021 gctatagctt ctataaataa aaatacatat gctggtgcag aaccacttgc accaattaca
    10081 gcttctataa gatactctgg tactacctca gtatttccaa aagaattaaa tacttctgta
    10141 actgcttcta agtcttcatt gtttatattt ttatttatag aaagagaaga catggcttca
    10201 tttacaagag ctggagtatt tggcatagtt ctaactattt ttttatcttc tcctataatt
    10261 gactctatat cctttataga ttttcctgct gctattgtaa ctataatttt attgtcatct
    10321 ataaagtctt ttatctcttc caaaatatca tcatatatat ctggtttaac agctacaatt
    10381 actatatcag aggttctagt tacttccttc gagtcttttg tagtatttat tccaaaattt
    10441 gcatctattc tatcgagagt tccttgacta tatgctgatg ctataaccat attaggttca
    10501 actaattttg aatttactat tccccctatc atagcgcttg ccatatttcc tgcacctatg
    10561 aatccaattt ttttcacttt agtacctcct tattgactaa tagtaatcgt taaaatttaa
    10621 gcttctttaa ctgcatcaga cttttcaaat ggatttggta tacttactac caaaattttc
    10681 actaccttat tagtatagtt gacccaatta tgattgttct tttcactatt atagtgtatt
    10741 gtgtctcctg gatacatttc tatttgttca tctcccaaaa acactgtaag agtaccctct
    10801 aatacataca caaattcctc accttcatgt acgtaacaac aaatttcctc actactctta
    10861 cttggaagaa tttcaattaa tcttggtagc attgtttttt cctttaaact agatgataaa
    10921 tgataatgta taaatgttga gttttctaca tcaaatactt ctttttcata acttcttaat
    10981 acagctcttt tatgctcttt tggcttcata aaaaagtaag ttaattctac atctagtaca
    11041 cttgctattt ttcctaagga atctgttgcc acacttgtta atcctctttc aagttgtgat
    11101 aaaaaaccaa ttgacaagtt tgttttttca ctcatatcct tcagcgtcat ttgcttttga
    11161 gttctgagtt gctttatttt tgctcctatg tccttattca aaaccatcac ccctaaataa
    11221 ttttaatttt ttcataatat aaatacaaaa atataaatat aggtactgaa cctatcttta
    11281 tttcatttaa aaaaaatttt tataagtatt actataattt atcaatcttt ttttgtctac
    11341 atttttacga ttatttacga tttatttttc acatatgtat atttaatctt gccaactaaa
    11401 gatacatttt ttataagcat ttactcttta tataataaaa cttaagttgt tcatgtagtc
    11461 ttcttctggt ttaattatta aaatttcaaa ttatattatt atttctacac attattacat
    11521 cctttagtac aattataaca taattttaca atttaatgat atctattcaa tgtctttttt
    11581 tactctacaa catattttat tttagagttt aatactatat atatttttta tatacagcct
    11641 tgtcattttt tagattgtca agagttattg aagtatttta tgtagattta tattttattt
    11701 tctaatttct catttaacaa gaattgctta tgataaaaaa taatatcatc tcaata
//
LOCUS       DAMJWO010000102        11738 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.105, whole genome shotgun sequence.
ACCESSION   DAMJWO010000102 DAMJWO010000000
VERSION     DAMJWO010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11738
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.105"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(65..265)
                     /locus_tag="PC366_003224"
     CDS             complement(65..265)
                     /locus_tag="PC366_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2578715.1"
                     /translation="MPKFICNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     gene            complement(267..617)
                     /locus_tag="PC366_003225"
     CDS             complement(267..617)
                     /locus_tag="PC366_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HDF2578716.1"
                     /translation="MIQKKIFMGFCGFLGFLSLRYFSSGNVTDLTYIGFFAFFSNFII
                     AKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNVELMCVLLSITYAIT
                     LNVYAIKLYILEEK"
     gene            779..967
                     /locus_tag="PC366_003226"
     CDS             779..967
                     /locus_tag="PC366_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2578717.1"
                     /translation="MTKYDFNFKLKVAKFYLNREGRDILIVKQYGVYDHSQVERWVNI
                     LGEGALKIKKFSILYGSS"
     gene            complement(1443..1593)
                     /locus_tag="PC366_003227"
                     /pseudo
     CDS             complement(1443..1593)
                     /locus_tag="PC366_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897489.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1990..2484)
                     /locus_tag="PC366_003228"
     CDS             complement(1990..2484)
                     /locus_tag="PC366_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDF2578718.1"
                     /translation="MKNKKGFTLVELLVVIAIIGILAIIALPALFKNIEKAKIAKLEA
                     DISAIKSASLSYYADESKYTDGGMISWVKKDGKIIINGGFKDDPLADKIENLGMPYNG
                     SYLLMSSPGHEKYLELSILPEGEISKSGLDKLKNDYGNLIDITNDQNKINIVIKLLNN
                     KSNT"
     gene            3290..3667
                     /locus_tag="PC366_003229"
     CDS             3290..3667
                     /locus_tag="PC366_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2578719.1"
                     /translation="MKEEILIEKLLRAELIVMEYLCKKDTLMPKKEIVKEIKQIYGWH
                     KSTIKILLKRLVAKRYLARYIINFQYHYKIIIDNKEYYTFKKKVLKSSKSIKIMRSLT
                     TTHKNVSKEKLDLLDEYYRNLKE"
     gene            3772..4147
                     /locus_tag="PC366_003230"
                     /pseudo
     CDS             3772..4147
                     /locus_tag="PC366_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            4759..5451
                     /locus_tag="PC366_003231"
     CDS             4759..5451
                     /locus_tag="PC366_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2578720.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIIGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            5647..7707
                     /locus_tag="PC366_003232"
     CDS             5647..7707
                     /locus_tag="PC366_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HDF2578721.1"
                     /translation="MEKYRALKLVSLIIISISFPLTILLATIGLAEPKYNIQKTSTKS
                     GIFNISNDFYDSNIFDEGTVESLLSNFKISVDSQLTSEEKSKLQTKSKSIDLSSNDSE
                     YDKIMINKQASEEYLSYLKNIKVYVINTYTGVFYTNTSYGNLDDFKQKTKSYCNIEII
                     NNVGKSSYIKTINGEKFELNNLSMELNGVDEAFEAYVSFPEEPTIEDGIVYTNFQIFK
                     QATEKVRLFFVACLSLAIVCLLSIILYSRIKGEVLKRNNVFLLIYSKIPMEFNVILVF
                     ISIAILTMYALAVSYHIDVIVLVSLSLLIVSNNIFFINVQLSYLENKMCIFKTSIIVR
                     VILWLIKTVREVSNAIKKVSLARKVIVIVIISLALIMVISTRSIGMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYIKVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVALQGGKFYIEIDGDLFKANLEFQKYEEEI
                     TNME"
     gene            complement(7913..8236)
                     /locus_tag="PC366_003233"
     CDS             complement(7913..8236)
                     /locus_tag="PC366_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HDF2578722.1"
                     /translation="MNNNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLYLSIANPKIISFMIVLLVAYKFKSIGISIITGVISIYL
                     FGIIL"
     gene            complement(8229..8930)
                     /locus_tag="PC366_003234"
     CDS             complement(8229..8930)
                     /locus_tag="PC366_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HDF2578723.1"
                     /translation="MERTQQLKESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEESYE"
     gene            complement(9208..10593)
                     /locus_tag="PC366_003235"
     CDS             complement(9208..10593)
                     /locus_tag="PC366_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDF2578724.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALAEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIIKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTSDSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGIQLIPIK
                     QEDNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYREALSSALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPDGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESTEELKAGL
                     SVLKRLLEEKK"
     gene            complement(10701..>11738)
                     /locus_tag="PC366_003236"
     CDS             complement(10701..>11738)
                     /locus_tag="PC366_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HDF2578725.1"
                     /translation="YKHNLDNYIPYDQGITLDIFMYIWILGIIAISFYYLRTNFKFYN
                     YIENFKKEILEIDITSILDEQAKELSINKKLQIYKVKGIYSPAIIGLTRCKIIIPEKK
                     YNNKELRFIFKHELIHYKRKDNLFKLLISIICIIHWFNPILYLLKKYFHELCELSCDE
                     IVIDKCTTSEIKEYAYIILNTIKYQKTLKYSSFVSQFLNKKNIILKKRLNSMFNQDKK
                     KINLGLKFLLTFIIIGSIFSINSNFKQNEDVEYTIAKINYNKNGETYGTHIIDSNGNS
                     IEPELIQTIGRGKKVGYVKKRDLYDCDNQPKTPEEAVLYTRKRNFNIFKKTIPLYDKE
                     GIKIIGRFEIN"
BASE COUNT         4627 a         1325 c         1563 g         4223 t
ORIGIN      
        1 tcaggagtga cttaaagatt gaatttaagt ttgtatttaa aacacatttt taataatgca
       61 aaaactaatc aaaaataaac aattcatcaa taggtgtatc tactattttt gatatatcta
      121 ttgctaattt caaagaagga ttatactttc ctgcttctaa acgcataatg gtttctcttc
      181 taactcctac tttttctgct aattgttctt gagttaattc ttttaattgt ctatattttt
      241 ttaggttaca aatgaatttg ggcatattat ttttcctcta aaatataaag ttttatagca
      301 taaacattta aagtgattgc atatgtaatt gatagtaaaa cacacattaa ttctacattc
      361 ctagacacta tagtaataca ccataaaatg aataattcta taatagcaag ctgtcctgta
      421 aatgccatag ctgctttttc atcttgtaca tacctttcat ctgctttatc accatttatt
      481 tttgctataa taaagtttga gaaaaaagca aaaaatccaa tatatgtaag atcagtaaca
      541 ttgccagatg aaaaatatct aagacttaaa aatccaagga aaccacaaaa acccataaaa
      601 attttttttt gaatcatttt ttatcctcct tagtaatttt aaaagagata tatttgtatc
      661 tttataatac aaatatatct cttttatatt cttttgtcaa tagaaaatca gtattataca
      721 atatttgtac tgcaccataa ttgttagagt aaaaatctaa cgcttgagat gtttatgtat
      781 gactaaatat gattttaatt tcaaattaaa agtagctaaa ttttatttga atagagaagg
      841 aagagatatt ttaatagtaa aacaatatgg agtttatgac cattctcaag ttgaaagatg
      901 ggttaatata ttaggagagg gtgcactaaa aataaaaaag ttttctatac tatatggttc
      961 aagttagatg ttataaacta tatgatgata actaagtata gtgtacaata aatcgctaag
     1021 tattttggaa taaacaatag cacagttata gcaacatgaa aacaaaaatt tttacatagt
     1081 ggtgttgatg cctttttcaa aatgaaagga agaccataat gaataaaaac aaaaacacta
     1141 aagaaaaaat aaattaacaa gagaacaaga attagaatat gaaaataaat ttttaaaaga
     1201 tgagcttgag tttttaaaaa agatgtgtgc ctcagggaag ccacattaaa aatagtggta
     1261 tcattattaa tcaaaagaaa gttagatgta ttatcaaaaa attagaactt aaatgcatag
     1321 cattttttca taaatcacat aaatataact cctataaagg tacaattgga aaagtaaaaa
     1381 ataataaaat aaatagaaga tttaaaacat caatagcata tcagaaaata acaaatgata
     1441 tgctagaatt tataaaatat atctaattat aaaaaaggca tatctcgatt cattttttgt
     1501 tatattgtca aataagaata ctatagatga aagatacgat tttgcagatg tattaagtaa
     1561 gtattctgat gtttttggtt gatacacatg caataaagaa gttgtgtttg cagataaatt
     1621 agcaaaacta tagtataagt tgcaacaata aagagaatga aaattatcat actaaagcat
     1681 aagacatgtt acaattttat tagataggac attaacatac actaaagtac tttttattat
     1741 aaagagtgct tatttttttg aaattcatta atgtataaac tatcaagaat attactcaac
     1801 acaatttaaa aacaacttaa ataggtattt ttagcaacat aaattatgtg atataataaa
     1861 aaatagaagt gtatgccaat acacttctgt agttataact aagcattcta ttcttgggga
     1921 gtgctttttt catttctcca aacaagattg tttatttcat cagtaattat taaatcaaat
     1981 ttattgtatt taagtattcg atttattatt taaaagtttt attacaatat ttattttatt
     2041 ttgatcgttc gttatgtcta ttaaatttcc ataatcattt tttaatttat ctagaccact
     2101 tttgcttatt tctccttctg gaagtatgct taattctaga tatttttcat gaccaggaga
     2161 tgacattaac agatatgaac cattataagg catccctaaa ttttctattt tatctgctaa
     2221 tgggtcatct ttaaaacccc catttattat tatttttcca tctttcttta cccatgatat
     2281 cattcctcca tcagtatact tggattcatc agcatagtaa ctaagagatg cactttttat
     2341 tgcacttata tcagcttcaa gtttagctat ctttgctttt tctatatttt taaataatgc
     2401 tggaagtgct attattgcca atattcctat tatagcaatt actactaata attccactag
     2461 agtaaatcct tttttatttt tcatttattt cccctccata taaaattaat aatatataaa
     2521 tttttatttt gttgatttct actttctata ttttaccata tatagacaaa aaaatcactt
     2581 tctatgacaa atatactatt attttacaat ttatagaaat gatttaaaat gacatttctt
     2641 gttagaaaag atataagcaa tggattaaaa taaagaaaac tacagtcata tcaatgtcaa
     2701 taatattatt taaaagcaga tgaaaataaa aagaggaccc agaaaataat gtctatttaa
     2761 ttatacttac ttaccaatac cataacttga tataaacaag attatactac atttttttta
     2821 tgctctatta taaaatcatc taactgtgta tctataaaat caaaataatt atatgaatta
     2881 tcagtataat aagtcaaaat atgtatacat gaatacatat ttttaaaaga tatatattat
     2941 tacataccta aaaaactttc ataaaaacaa aaataaaata tgcttttagt aacttgttaa
     3001 cataacttat aatttatttt ataagcatta gcctatatag ttttgtgcta ctaaatttct
     3061 ttgattctaa cgatttagtg ctattctaca actaaaataa tacaatagag ctatttattg
     3121 tttggtagca ttgtttgcaa attaaacaaa tatatatata tgaatattat tttacgttta
     3181 aaaaaacaga ctaaatatgt agaatatttg gtaaaactta cctctagttt ttgtcttaaa
     3241 aagctcctat tattaattta agttagaaga attaaggaag tgacataaat tgaaagaaga
     3301 aatattaata gaaaaattat taagagcaga attaatagta atggagtatt tatgtaaaaa
     3361 agacactcta atgcctaaaa aagaaattgt aaaagaaata aaacagattt atggatggca
     3421 taaaagtaca ataaaaatac tactaaaaag gctagttgct aaaaggtatt tggctagata
     3481 tattataaat tttcaatatc attataaaat aataatagat aataaagaat attatacttt
     3541 taagaaaaag gtactaaaat ctagtaaaag cataaaaata atgcgttcac ttaccactac
     3601 acataaaaat gtaagtaaag agaagttaga cctattagat gagtattata gaaatttaaa
     3661 agaatgatat agtaaaaatc gaatgtaatt atttacctta attcttttgt ttgtaaaact
     3721 ttattgatat agaatttaac atatacataa attggtaaag ggatgtatac tatgaaaatt
     3781 agtaaattac cagaagcgga attaaaagtt atgagatata tttgggaatc agaaaaggta
     3841 ttaatatcaa gagaaatcac caagtctatg gaacaaaaat atgaatggaa agatacaact
     3901 atatttacag tattaaaaag attactaaag aagagagttt ttagaaacgg agaaaataga
     3961 taagcgtaca cactataatg tattagtaaa agaaaaataa tatcagagat tttaaacaaa
     4021 agaattttta aagaatacac ataaaaattc aatattaagt ttaatgtcag cactatgtag
     4081 taaggatgat gaagtagatg gtgatatttt aaatttatta gaagaatatt ttaagaattt
     4141 aaaataagaa aatgacagct agatacataa taaataaaat gaaggtatga aattataact
     4201 ttttctacat tcattttgtt tattattctg aacatgttaa aaaaatgaaa taagtttgta
     4261 ttttatttat ataaatttta atagaatatg tacagtatat agtagataga atgtataaaa
     4321 atagaattta aataagtagc tattattgca gtgaaataaa tgtttctaag tatatttggg
     4381 tggaagaatg gtggaagaaa attagtgaaa tgtaattctt ccaccattct tccaccccaa
     4441 aaataaaaac tgttcaataa gaattaatat acattaattc agctgaatcc aatcaaaata
     4501 cttaaataaa agtaatctga aaataacata attcaaatca atttattcaa ataaatctca
     4561 atttatctta aatcttaaga aatatttaag aattaggata atattttctt aagatttata
     4621 ttttattata tagttataag ggaaagttac aaaaatgtaa gccaaagtaa tataacaatt
     4681 tagtcattgt tgagaaagta agtgaaagat attgtataat atagataagt attattatac
     4741 aatagaggaa gtgaaaatat gtacaatata ttagtagtag acgatgataa agaaattgtt
     4801 gattcaatag aaatatatct taaatcagaa ggatttaaaa tatataaagc atatgatgga
     4861 atgaaagctt tggaaataat aacagagaat gacattcatc taatactaat ggatataatg
     4921 atgcctaaat tagatggaat caaagcaact gtaaaaatac gagaagaaag aaatattcca
     4981 ataattttaa tttcagcaaa aagtgaagat acagataaaa taataggatt aaatattgga
     5041 gctgatgatt atataacaaa gccatttaat ctattagagc ttatagctag ggttaaatca
     5101 aacttaagac gatatgtaac tttaggtaat tatgaagata catgtaaaga aattttaaaa
     5161 agtggagctt tggagttaaa tacactaaca aaagaagtta aaattgatgg tgaaaacata
     5221 aaaatgaccc caattgagta taaaataatt gaacttcttt tagaaaataa aggacgagtt
     5281 ttctcaatag atgagatata cgaaaaagta tggaatgagg aaagttttaa ttcagaaaat
     5341 acagtagcag tacatatcag acgaataaga gaaaagattg aaataaatcc aaaagaacca
     5401 agatttttaa aggtggtgtg gggagttggt tataagattg aaaaatttta gtggaaaaat
     5461 tataaaagaa aagagtttaa tatttaattg cattttgatt ttagtcattt ttacatttac
     5521 acaaatgtta ggaattttaa tatgttttaa ttttttctct gagagtttaa tttactctat
     5581 ggggattatg cttttcttaa actttatttt atataaaata ctgacaatgt agatgaggtg
     5641 ggcaacttgg aaaaatatag agcattaaaa ttagtttcat taatcataat atctatctca
     5701 tttccattaa ctatattgtt ggctacaata ggacttgctg agcctaaata caatatacaa
     5761 aaaacttcta caaagagtgg gatttttaat atatctaatg atttttatga tagtaatata
     5821 tttgatgaag gaacagtgga aagcttatta tctaatttta agatatctgt ggatagtcag
     5881 ttaactagtg aagaaaaaag taaactccaa acaaaaagta aaagtataga tttaagtagt
     5941 aatgattctg agtatgataa aatcatgatt aataaacaag cttctgaaga atatttaagt
     6001 tatctaaaaa atataaaagt gtatgttatt aatacatata caggagtatt ttatacaaat
     6061 acatcatatg gtaatttaga tgattttaaa caaaaaacta agagctattg taatatagag
     6121 ataataaata atgtaggaaa gagctcgtat attaaaacaa taaatggaga aaaatttgaa
     6181 ctgaataatc tgagtatgga actaaatgga gtagatgaag cctttgaggc atatgtctct
     6241 tttccagaag agccaactat agaagatgga atagtataca ctaattttca aatatttaaa
     6301 caagctacag aaaaagtaag attatttttt gtagcttgtt taagtttagc aattgtgtgt
     6361 ttattatcta tcattttata tagcagaata aaaggtgaag ttttaaaaag aaataatgta
     6421 tttttactaa tatacagtaa gatacctatg gaatttaatg taatactagt atttatttca
     6481 attgcaattt taactatgta tgctcttgct gtatcttatc atattgatgt aattgtatta
     6541 gtttctttat ctttactgat agtatcaaat aatatatttt ttataaatgt gcaattgagt
     6601 tatttagaaa ataaaatgtg tatatttaag acaagtatta tagtaagagt gattttatgg
     6661 ttaataaaaa ctgtaaggga ggtcagtaac gctataaaga aagtatcttt agcaaggaaa
     6721 gttattgtta tagtgataat atctttagct ttaatcatgg taattagcac tcgaagtata
     6781 ggtatgggat tactgttttc tatatgtatt tttttaggat ttacaatata tataactaaa
     6841 agactttcat atcttagtta cgtaatagaa ggtacagaaa gaataaaaaa gggagaatta
     6901 gattataaga taaaaattac tgggaatgat aattttacgt ctttagctga aaatataaat
     6961 aatattggag aaggtcttga tagagctata gaagagcaag taaaaagtga aagaatgaag
     7021 tctgatctta taacaaatgt atctcatgat ttgaaaactc cacttacttc tataataaat
     7081 tatgtagatt taattaaaaa agaagaatca atacaaccag agtatataaa tgattatata
     7141 aaggtacttg agtcaaagtc aaaaagacta aaattattga tagaagattt atttgaagcg
     7201 agtagagtaa gtagtggcaa tatagaatta caaattagca agattgattt agtgcaacta
     7261 ttaagacaaa gcataggtga acttgaagaa aaattatcta aaaataattt atatttaaaa
     7321 ttaaatgttc caaatgataa ggtgtatata tgggcagatg gaagaagaat gtatagagta
     7381 tttgaaaatc ttttatctaa tatagcaaaa tattccttag aagaaactag agtctatatt
     7441 gatgtatatg actatggtga aaatgtaaag gtaactatga aaaatatatc ttcttatgaa
     7501 ttaaattttg acccaagtga gattatggaa agatttaaaa gagctgatga atcaaggaat
     7561 actgaaggaa gtggattagg gcttgctatt gcaagagatt tagtagcttt acaaggtgga
     7621 aaattttata tagaaataga tggagattta tttaaagcaa atttagagtt tcaaaaatat
     7681 gaagaagaaa taacaaatat ggaatgagat agtatttaag tatatatatt ttttttactg
     7741 tcgaaagctt ttattataat atattagaat atttacagta gagaatgaag agtaaaaaca
     7801 gagtaacttt aagtcactct gttttttatt taaaatcaat aatataacaa cttaaattaa
     7861 aattgtacac atagttttaa aataacttat acaataaaac attatccaaa tatcacaaga
     7921 taattccaaa taaatatata gatatcactc ctgtaataat agaaatacca atagatttaa
     7981 acttatatgc aacaagaagt acaatcataa aagatataat tttagggtta gctatagata
     8041 aatatagact atctccatta aaaaatacat ctttagcagt taaggaagta agtattgcta
     8101 caggtataaa tttcatgatt tttttcaaaa aatcaggcat ctcttttttt gaaaaaatta
     8161 acataggaag cactcttggt agatatgtaa caatgtacat tccaattata ataaaaaata
     8221 tataattatt attcataaga ttcctccttt ttacagtaag attcttctat aaagaaacca
     8281 attaaagatg ctaaaattga tgcaactatt attactaaat tgcttttgaa taatgcatat
     8341 aaaataacag aaataatgat tgatgatata aatactacaa tataaatctt attttttatt
     8401 tgagaaacta ttaaagctat aaacatagaa gtcaatatga agccagaaat agaactgtct
     8461 atagatatac tttctcctaa aaatgctcca ataaaattag ctaaaactga tgaaattaag
     8521 cagaagaaat taagataaat agcatttcta tcagaccaat ttccagcagt aaatttttca
     8581 taattaactg caaaagtttc atctgttata gtatgacaaa atggcaatat aaattttgga
     8641 cttttatttt ttatgtacat gttcaaatta gaactcatta gaaaatgtct taagttaact
     8701 ataaatgtag tcaaaacaat agatgttaca cttgcaccag tagaaatcat tgaagctgca
     8761 atgaattgag aacttcctcc aaatactaaa gttaccatta gtgctatttg aaaaggtgaa
     8821 agaccagatt tttgtaatag tattcctcct actataccta taggtatata acctaagaat
     8881 ataggaattg aagcaataaa gctttctttt aattgttgag ttctttccac aataaatcac
     8941 tccttttgta ttaaatgtat taaagtatta gtaaaacaga aaaatagatt aattgtataa
     9001 ttgcaattat aattaaaaat aaatttggat taatatataa aatactatac aacaaataaa
     9061 taatcttaaa cggttattaa attttatcta tttgttatta tgatgtaata atacatatta
     9121 atctctataa gttaattact atctggtgta attttatttt aacaacaaaa aaaaatacac
     9181 acaattaaaa tattgtgtgc aatacaatta ttttttctct tctaatagtc tttttaatac
     9241 gctcagacca gctttaagtt cttctgtgct ttctgtagca catacagcta ttcttattgc
     9301 agaaattggt ttttcttttc caacagcaaa acgttcagaa gcatagacct gtacaccttc
     9361 tttaagtgct tgtatctcaa atttttctgc cattattcca tcaggtagaa tcaaccatct
     9421 aaatatacat tcttcatttc ccaaaagatt atatccagat aaatattgat taataatctt
     9481 gtttcttctt cttgcagatt tacggcgtgc attaattaat ttatcggctt cacctgatgt
     9541 aatcatgcga taagcaattt ctgttaaaaa ataagattga gatagattaa tgttgtataa
     9601 tgcgcttgat aatgcctctc gatactgttt aggtgtagag atatatgcta gccgtaaact
     9661 aggtgcaata atttttgata aactcgtaat ataaattgtt tgattgggca gataggaagc
     9721 cactggattt aaatgtgttt cattaagtaa actatgaata gcatcctcaa taacaattaa
     9781 attgtattta gatgcaatat ttgcaatcat ttttcgtcca ttttgtgaca ttatatgtgt
     9841 agttggattt tgataatctg gtattatgta tagaccttta atattttcat ttttacaagc
     9901 atataatagt ccttcttcac taatctcatt atcttcttgt ttaattggaa ttagttgaat
     9961 cccaagcatt ttagctgctg tctttattcc aggataagtt aatgggtcta cacctattct
    10021 atctccatgt tgaaacaaac cagctaaaat agcaacaatt gcattttgtc caccacttgc
    10081 aggaagtaag ctatctgatg tagtttcaag cccagcttta taaattaatt tggcaatagc
    10141 ttctttttgc catttagcac catctctttg tccatattgg aatatagttt taaaatctat
    10201 ttccttaatt atatgtttaa acaaagtatt catttcttct agtgtgaaat ctggattcat
    10261 tgtgcccatt tcaataaatg taattttatt attactggac atcaagaata gatttgaacg
    10321 cgtatcataa gatacaaaag ttccacttcc tgtaactcca cttattagac cttttttttc
    10381 acaaatttta aaagctctag agatagtact cacattaaca tctaagaaat ctgccaattc
    10441 acgttggggt ggtaatttag tacctggtaa taaaaatcca ttgttgatat cttgttctag
    10501 ttgttctgca agcgccttat ataatatttg cccttttgaa ggtctctttg gtttccagtt
    10561 cataggataa ttttcaaaag aattaattgg cataagtttt cacctcacat tattaatttg
    10621 attttttctt tatctaaaac aataaattct aaagatacaa ataaaaactg ataggaaata
    10681 attctatcag tttttgtctt ttaattgatt tcaaatcttc ctataatttt tataccttct
    10741 ttatcataaa gagggattgt ttttttaaat atattaaaat ttctttttct tgtatataaa
    10801 acagcttctt ctggtgtctt tggttgatta tcacaatcgt acaaatctct tttttttacg
    10861 tagccgactt ttttacctct acctattgtt tgtataagtt ctggttcaat ggaatttcca
    10921 tttgagtcta ttatatgtgt accataggtt tctccatttt tattataatt aatcttagca
    10981 atagtatatt ctacatcttc attttgttta aaattggagt tgatagaaaa tattgaccct
    11041 attattataa aggttaataa aaacttaaga cctaaattaa ttttcttttt atcttgatta
    11101 aacatagaat ttaacctctt ttttaaaata atattttttt tatttagaaa ctgagatacg
    11161 aatgatgaat acttcaaagt tttttgatac tttattgtat ttaatattat atatgcatac
    11221 tctttaattt cactcgtggt acatttgtca atcacaattt catcacaaga taattcacat
    11281 aattcatgaa aatatttttt taataagtat aaaattggat tgaaccaatg tatgatacat
    11341 attatactaa ttagaagctt aaataagtta tcttttcttt tataatgaat taattcatgt
    11401 ttaaagataa atcttaactc tttattattg tacttttttt ctggaattat tattttacag
    11461 cgtgttaaac ctataatggc aggggaataa atacctttaa ccttatatat ctgaagtttt
    11521 ttatttatac ttagttcttt tgcttgttca tctaagatac tagtaatatc tatttctaaa
    11581 atttcttttt taaaattttc tatgtaatta taaaatttaa aatttgttct taaatagtaa
    11641 aaagagattg ctataattcc taatatccag atgtacataa atatatctaa agtaatgccc
    11701 tggtcatatg gtatataatt atcgagatta tgtttata
//
LOCUS       DAMJWO010000103        11502 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.106, whole genome shotgun sequence.
ACCESSION   DAMJWO010000103 DAMJWO010000000
VERSION     DAMJWO010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11502
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.106"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            193..738
                     /locus_tag="PC366_003237"
     CDS             193..738
                     /locus_tag="PC366_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDF2578726.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNRATNKA"
     gene            751..1764
                     /locus_tag="PC366_003238"
     CDS             751..1764
                     /locus_tag="PC366_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDF2578727.1"
                     /translation="MEENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEIVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVNPNCISVVDGEDMPQKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     ARVISPLAGNIGGLLIISVICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPIAVIIAYGVAVF
                     ALR"
     gene            1986..3959
                     /locus_tag="PC366_003239"
     CDS             1986..3959
                     /locus_tag="PC366_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDF2578728.1"
                     /translation="MSVTEKIPSIDRKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAVIKYIKGQGYKLEIKDEQILNKIIDMNRKNVFSLNSKEDRVEF
                     ILNYLIELDGFITLDSLADEMCVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFSNSKYFKGIKKEEIINLEEKLLTLFKENNFYVTDEML
                     REVINYIVVLVYRVKEEKKVKDYDVKFDLLKSYDEYFIAREIKHIISGMFECTLNDEE
                     IIYLTIPLVSGNAPASECALNSSRISKNIDELMENIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILASLEKMMDHLMDLGCIDDKFRKNIVNREEKSPTVFD
                     KGLLFPHSVNEKSDKFLMAVGILEEPIEYANRSIKIILMTMFPCENKIDSDLLVKIYE
                     EVLKIGQDVKLTNKISKCRTFLEFKKVLLKNLI"
     gene            4028..4387
                     /locus_tag="PC366_003240"
     CDS             4028..4387
                     /locus_tag="PC366_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578729.1"
                     /translation="MKLLVILFVAYILNTIFIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAIISSDSDGFIKFGEILKGRTVMAKFKEIEEIEGLDIYSAEQKFKDEES
                     IVQAIKFIKEKINVSFN"
     gene            4422..4778
                     /locus_tag="PC366_003241"
     CDS             4422..4778
                     /locus_tag="PC366_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDF2578730.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     IATLKSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKCEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            4815..6107
                     /locus_tag="PC366_003242"
     CDS             4815..6107
                     /locus_tag="PC366_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDF2578731.1"
                     /translation="MLDLNRKLAKLEEEGKKIKVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDINLELAHKAFTDAGIDEEIIDNVTNEKDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAERKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLDHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEFMDGYGAYTCYGTIEKYDVAKAMNAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            6543..7181
                     /locus_tag="PC366_003243"
     CDS             6543..7181
                     /locus_tag="PC366_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2578732.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            7188..8030
                     /locus_tag="PC366_003244"
     CDS             7188..8030
                     /locus_tag="PC366_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HDF2578733.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            8091..10718
                     /locus_tag="PC366_003245"
     CDS             8091..10718
                     /locus_tag="PC366_003245"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HDF2578734.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRAEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDKALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGIEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            10932..11177
                     /locus_tag="PC366_003246"
     CDS             10932..11177
                     /locus_tag="PC366_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDF2578735.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKK"
     gene            11389..>11502
                     /locus_tag="PC366_003247"
     CDS             11389..>11502
                     /locus_tag="PC366_003247"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2578736.1"
                     /translation="MSKKHKKYSKELKLKAVNLYIKEGYSSYKIAEMLNIRS"
BASE COUNT         4592 a         1175 c         2198 g         3537 t
ORIGIN      
        1 ttagtacaat tttttccttt ataaaattga aaaaagatgt atttatttat caaaaatatt
       61 atattaaaat gatattaata aaaaaacatt tacaatatta gcatatagta cagaaaaaag
      121 atgtaatttg taaaatttat gttaagcagt aaaattaaaa atttaaagat attataggga
      181 ggttataatt ttatggaaaa cgttattaca ggtctaagta aaggtgcaga gtggtttatc
      241 ggtttgtttc agaaaggggg agaacaattt ataggtcttg tttcaggtac tcttccaacg
      301 ctaattgtat taatggtagc tattaactct ttgattaaga taattggtga ggaaagagtt
      361 aataattggg cttctaagct aggaaagaac tcttttacaa gatatattct acttccatta
      421 gtatcagtat ttttcttggg aaatcctatg tgctatacat ttggtagatt tttaaaagaa
      481 gagcacaaag caggatttta tgatgcagca gtttcatttg tacatccaat tacaggtctt
      541 tttccacatg caaatgcagg agaacttttt gtatggttgg gaatatcagc aggtttgact
      601 actttaggta aagaaactac tacactggca ttgtggtatt ttatagttgg tctaattgta
      661 atttttataa gaggtatagt aacagaaaaa atgtatgctt ttctaacaag aaaaaataga
      721 gcaacaaata aggcttagga ggtagataaa atggaggaga ataaaatatt aaaaatagaa
      781 aagggaactt caggctgggg aggtcctttg tatataaaaa aagaagggaa tagaaataag
      841 atactatcaa tgactgctgg tggtatccat gaagtaacat taaaaataaa agaactactg
      901 ggttgtgaaa ttgtagatgg atttaaaact ggagtttctg atgaagaagt agcagtagtt
      961 attattgatt gtggtggaac tgctagatgt ggagtttatc caaagaaaaa aatacctaca
     1021 ataaatgtaa atccagttgg aaaaacaggt cctttagcaa aatttataac agaagaatat
     1081 tatgtatcag atgttaatcc taactgtata agtgttgtag atggggaaga tatgccacaa
     1141 aaatctcaag aaaataaaag cgaaaataag agttctatta gaaagcctga taattatgat
     1201 gaggttaagt caaaagcaca aggtgaatat gctaaaaaga acataatact ttctattggt
     1261 caaggggcag ggcaagtagt atcaaaattt tatgatgcag gtcgagacac tatccaaatg
     1321 gtaatgaata acgtaatacc atttatggca tttgtaagta tgcttatggg aattatttta
     1381 gcatctggac tgggagactg gattgcaaga gttatatctc cacttgcagg taatattggt
     1441 ggattattga ttatatcagt aatttgcaca cttccattct tatcaccaat actaggacct
     1501 ggtgcagtta tagctcaagt agtagggact cttgtaggta cacaaattgg tcttggtgca
     1561 ataccagcat atttagcact tccagcttta tttgcaataa atgggcaagc tggatgtgat
     1621 tttgtaccag taggattaag tttgggagaa gcagaaccag aaactgtaga gtatggtgtt
     1681 ccagctttat tttactctcg tttaataact ggtccaatag ctgttattat tgcatatgga
     1741 gttgcagtat ttgcattgag ataatattta atgtcaatat aaggcttgga attaattaat
     1801 aaaattgtaa atataaattt aagctagtca agattttttg ttaatgaaag actagctttt
     1861 atactattaa ttagctgtaa ttatcgagtt agattaatac taaattttcc tttattaaag
     1921 tgaaatttta tgtattaatt tggtttcaaa tttgtactag aatgaaatca aggaggagat
     1981 acaaaatgag tgtaactgag aaaattcctt ctattgaccg caagatattt aagatattga
     2041 ttatgtgtag taaaaaagag tttgtgagta ttaattcaat agcaaatgaa ttgaatgtca
     2101 caactagaag tgtaaggacg tatataaaac aattgaataa agatttaggt aatgatatag
     2161 cagtaatcaa atatataaag ggtcaaggct ataaactaga aataaaagat gagcagatac
     2221 tcaataagat tattgatatg aatagaaaaa atgtattttc attaaattca aaagaagata
     2281 gagtagagtt tatactaaat tacttgatag aactagatgg atttattaca cttgatagtt
     2341 tagctgatga gatgtgtgta ggaagaacta ctttagtaaa tgatttccag tatgtagaaa
     2401 aagttttggc ttcatataat ttaaacttga ttaaaaaaca gaatacaggt atgaaattaa
     2461 atggaaatga acttgatatt agactgttta tattaaatca gttgtataaa aactcaagga
     2521 aagatttcag taattcaaag tattttaaag gaatcaaaaa agaagaaatc ataaatttag
     2581 aagaaaaact attgacttta tttaaagaaa ataattttta tgttacagat gaaatgttaa
     2641 gagaagttat taactacata gtagttttag tctatagagt aaaagaagaa aagaaagtaa
     2701 aagactatga tgtaaagttt gatttactta aatcatatga tgaatacttt attgctaggg
     2761 aaataaaaca tataatatca ggaatgtttg aatgtacttt aaatgatgaa gaaattattt
     2821 atttaactat accattagtt agtggaaatg caccagcatc agaatgtgct ttaaatagta
     2881 gtagaattag taaaaacatt gatgagttga tggaaaatat atttaatcaa atatatgtcg
     2941 atatgggtat ttttataaat gaggatgaat taagagtagg tctaggatat catcttagtt
     3001 ttactttaaa caggctatta tttaatataa agttaaaaaa tgttttgtta gaagagatta
     3061 agcaaaatta tatacttcca tttaaattag cacaaatagc aggaaaagta atagagaaaa
     3121 agtataactt agaagtttca gaagatgaga ttggatatat agcaatccat ttcagtggat
     3181 atttagaaag aaatagcagt agattctatt caataaaaaa aatagcaatt atatgtagta
     3241 caggtctagg aacagcaaaa ctattgaaaa taagagtaga aaaactgata ggaaataatc
     3301 ctaaaattga tactctttca agttttaatt tgagaaatat taacttagat gaatacgata
     3361 tagtttttac aactattgat ttagacacat cgaatataaa tacaatagta ttaaaaataa
     3421 atacaatatt tgatgaaaac aaattaagag aacaattaaa aacagtattg tgcctaagag
     3481 aagggaatat tgacactact aattctacaa atttactaat aaataatttg ttagatgaag
     3541 ataaatttat gatattaaat gaaaagacta tacttgcttc attagaaaaa atgatggacc
     3601 atcttatgga tttgggatgt attgatgata agtttagaaa aaatatagtc aatagagaag
     3661 aaaaatctcc cacagtattt gataaaggtt tattatttcc tcactctgta aatgaaaaat
     3721 cagataagtt tttaatggca gttggaattt tagaagaacc aatagaatat gcaaatagaa
     3781 gtataaaaat aattcttatg acaatgtttc catgtgagaa taagatagac tcagacttat
     3841 tagtaaaaat ttatgaagaa gttttaaaga taggccaaga tgtaaaatta acgaataaga
     3901 taagtaaatg tagaactttt ttagaattta aaaaggtgtt acttaaaaac cttatataac
     3961 tattgtacag catttatagt tgttatacag atttaaaaat aatgtgattt ttggaaggtg
     4021 tataaatatg aaattattag taattttatt tgttgcttat attttaaata ctatatttat
     4081 aatgaagcag aataaattgt attttaaaac tttaaataga gctaaaaaaa agggtgatat
     4141 agtgtctaca ggcaaaaaga aaagctattt ttctaaagga agtatagcca ttatatcttc
     4201 agattcagat gggtttataa agtttggaga aattttaaaa gggcgtacag taatggctaa
     4261 atttaaagag attgaagaaa tagaaggatt agatatatat agtgcagagc aaaaatttaa
     4321 agatgaagag agtattgtac aagctataaa atttataaaa gaaaaaataa atgtttcttt
     4381 taattaactc aatataaata taaattatca ggaggaatgt catgaaatat gaagttaaga
     4441 taagtgggat aggcagttta gttaaagagt taatggatga aagcaattgt cttattatat
     4501 atgatgaaac cattaatgat gacgacttaa aggatatatc tgtaattcat tcgatagcaa
     4561 cattaaaaag tgatgttgaa ataggagata cacttactat agggaataga gattattgta
     4621 tagtttcagt tggtgatatt gctcagaaga ctcttagaga aattgggcat tgtacaatca
     4681 aatttgatgg aaaatgtgaa gtaaatttac caggagaaat acatgtggaa ataggaaatc
     4741 cagatataac tattggagat ttaataacta tttcttaatt tgaaaataaa attattataa
     4801 caggaggaat tggtatgtta gatttaaaca gaaaacttgc aaaattggaa gaggaaggta
     4861 aaaaaataaa agtagctctt ataggagctg ggcatatggg aaatggaatg gtaagccaaa
     4921 tggcaaatat gaaaggtatt gaagcttcta ttgttgtaga tataaatttg gagttggctc
     4981 ataaagcttt tactgatgca ggaatagatg aagaaattat agataatgta acaaatgaaa
     5041 aggatgcaga aataaaatta caagaaggaa aagtattgac atgtaatgac tttcttgtgg
     5101 cttgtaaaac taagtcaata gatgtagtta tagatgcaac tgggggtatt gcaattggtg
     5161 cagagatagc attaaactct attttaaata aaaaacatat agttatgtta aatgctgaaa
     5221 ctgattgtgt tgttggacca atacttaaaa aattagcaga tgatgctgga gtgatattta
     5281 caggttctgc aggagatgag ccaggtgcag taatggaatt atttgatttt gcagatgcaa
     5341 tggggtttga agttagagtg ataggtaaag gtaaaaataa taaattagat ttagattgta
     5401 atcctgatac agttagagaa gaagcagaaa gaaaaggagc ttcacctcat atgatagctt
     5461 cttttaaaga aggaactaaa acaatggtag aaatggcttt aatgtgtaat gcaactggat
     5521 ttgtgcctga tgtaagaggt ggtcatggta ttgaagctac agttaatgaa gtacctaaga
     5581 aatatgcatt aaaaagcgaa ggtggagtat tagataatta tggtgtagtt gattttgtaa
     5641 atggtatagc acctggagtt ttcgtagtag tagcccataa attaaaagca gttaatgatg
     5701 aactaaaata tttaagtatg ggtgatggac ctaattacat attatataga ccatatcatt
     5761 tatgtagttt agagactcct ttatcagcag ctatggcagt cttagaccat aaggctacaa
     5821 tagtacctaa agctggacta gtagcagaag ttatgactat agctaagaaa gatttgaaaa
     5881 aaggtgagtt tatggatggt tatggagcat atacatgcta tggtactata gaaaaatacg
     5941 atgtagcaaa ggctatgaat gctgtaccta ttggtttgat aagtaaaaag actaaagttg
     6001 taaaagatat taaaaaaggt gaagttataa cttacgatat ggtagagata gaaaaagata
     6061 ctactttata tcatttaaga caattgcaag aaaaaatatt tgggtaagat ttgatggtaa
     6121 tataaataga tattagtaaa aagggttgat ggttattttt aaatcaaccc ttttaaattt
     6181 ttatatattc ttgttaggat actttcttta aaagtatatt ataggttatt tgtagtcgta
     6241 aaaattattt tgaattagtt ctgcaatttt atattcacat tgaaacaata ttattaaaaa
     6301 ttttaatata aaatgaatta aaatgaccaa ttatgtatta taatattaac tgtaatacta
     6361 atatagttct attaattaaa gaaatatccc ccattaatat ataataaata tctttaagcg
     6421 agagaactta gtaaaaaata tatcgtattc aataaaaaat ctgtttacag aatggtatat
     6481 atagttatat aatatactat ataagatgcg aaaagataaa aagtatagca caatgaaaga
     6541 aggtgattat tattcagctt aatgaaagac aactaaaaat tatagatata gttaaggaaa
     6601 atgaaccaat aacgagtgaa agtattgcct ccagcttgaa tgtgactcgt gctacactta
     6661 gatctgattt agctatatta acaatgacag gaatattaga cgcaagacca aaagttggat
     6721 atttttattc aggagttagt gaaataaatt taattggtaa aagtgtaaaa gaaaaaacag
     6781 tagaggatat aatgagcatg cctgtactag ctaagaagga tgaaagtata tatgatgtaa
     6841 tagtcactat gtttttatct gatgtaggga gtatagttat tatagatgag aatgaagagt
     6901 tatgtggagt tgtttccaga aaagacttgc taaaagcaac tataggaggt tctgatataa
     6961 ataaaatgcc aataggtatg ataatgacaa gaactccaaa tgtagtcact ttaactaaag
     7021 gagcaagtgt tttattagct tcaagaaaaa taatagaaca tgaagtagat tcgattccga
     7081 ttgttgaata taagggagaa gacaaaaatc atatgagagt tgttgggaga atatcaaaaa
     7141 ccaacataac taagctattc ttagaaatag ttgacaatta aggaggtatg ctggtgaaaa
     7201 acctaattat atatgcagta tcagattcag taggggagac tgcacaacaa gttgcaaagg
     7261 catgtatgtc tcagttttat gtgaatgaaa cttatgaaat aaaaagattt ccatacatga
     7321 ttaataaagg agtactactt gaaactttgg agaatgcaaa agctgaaaac gctttaattg
     7381 tatatacatt agttgatgaa gaattatgca gtattgttga aagatattgc gaaagagaag
     7441 gtcttagttg tatagattta atgacagata tactaagaga aataagcaag agaacaggaa
     7501 gaaaacctaa aagagaagct ggtataatta gaaaattaga tgaatcttac tttaagagag
     7561 ttgaagctat agaatttgca gtgaaatatg atgatggaaa agaccctaga ggtgttcttc
     7621 aagcagacat aattttagtg ggaatatcaa gaacatctaa aactcctttg agtatgtatt
     7681 tagctaataa aaatataaaa gtagctaatg ttccattagt tccagaaata ccaattccta
     7741 aagaagtgtt tgagatagat actaaaaaga taataggtct tactaattca cctgaaaagc
     7801 tgaatgagat aagaacccaa agattaaaag ctttaggatt gtccagtaaa gcaaactacg
     7861 ctaatttaga aagaatactt caggagttag attattcaga agagataatg aaaagaattg
     7921 gatgcccagt aataaacgtt tcaaataagg caatagaaga aacagcaggt ataattttag
     7981 acataatgaa agaaaatggt ctaaagatat acaaagaaat agaaatttaa taatgtctat
     8041 taataaaaat gatataaatt aaaataaaaa gattaatggg ggatttaaca atggaaacta
     8101 agtatgttta tagttttggt gaaggaagca aagacatgaa atctttacta ggaggtaaag
     8161 gtgccaattt agcagaaatg actaagatag gcttacctgt ccctcctgga ttcactataa
     8221 caacagaagc atgtaatgat tattatgtta acaatgaaag tataagagca gagataataa
     8281 aagaaataga agagcattta gctactttag aaaaagactt aaataaaaca ttaggatgca
     8341 ataagaatcc attattagta tcagttcgtt ctggtgcagt attctctatg ccaggaatga
     8401 tggatacaat tcttaaccta ggtcttaatg acaatagtgt tgttggctta gcagaggcta
     8461 cacaaaatga aagatttgca tatgatagtt acagaagatt catacaaatg ttttctgatg
     8521 ttgctatgga agttccaaaa tataaatttg aaaatgtatt agacagagta aaagaagcaa
     8581 agggatacac agttgataca gaacttacaa ctgatgattt aaaagaaata gtaaaagaat
     8641 ttaaagcaat ttataaaaaa gaaataaaaa atgatttccc acaagaccca aaagagcaat
     8701 taatgcttgc aatagaggct gtatttagat catggaataa tcctcgtgca atcgtatacc
     8761 gtaaattgaa tgatatagct cataacttag gaacagcagt aaatattcaa tcaatggtat
     8821 ttggtaatat gggagaaact agtggtacag gtgttgcatt tactagaaat ccagctacag
     8881 gagaaaataa attatttggt gaatttttaa tgaatgcaca aggtgaagac gttgttgcag
     8941 gtataagaac tcctcaaaat atatcaactc ttgcagatgt aatgccagct gtattcgatg
     9001 aatttgtaaa aattactcat atacttgaag gtcattataa agatatgcaa gatatagagt
     9061 ttactataga aaatgaaaga ttatatatac tacaaactag aaatggtaag agaacagcag
     9121 cagcagcaat aaatgtagcg gttgatttag ttgaagctgg aataattgat gaaaaagaag
     9181 ctatcatgag aattgagcct aatcaattag accaattatt acatccaaaa tttgaagata
     9241 aggcattaaa agaagccaag gttatagcaa aaggtttacc agcatcacca ggtgcagcaa
     9301 gtggtaaagt ttatttcaat gctgatgatg tagtaaaagc aaatgaaaaa ggagaaaaag
     9361 tagttttagt tagattagag acatctccag aagatataga aggaatggtt aaagcagaag
     9421 gaatccttac agctagaggt ggaatgacat cacatgcagc agttgttgct agaggtatgg
     9481 gtaaatgttg tgttgctgga tgtggagaaa taaaagttga tgagtttaat aaagaaataa
     9541 gagcacttga tgatgtagtt ataaaagaag gtgaatacat ttctatagat ggttctacag
     9601 gaaatgtgta cctaggagat gttaagaaaa cagaagtatc tttaactgga aactttgaaa
     9661 aattaatgaa ctgggtagac aaacacaaat gtatgatggt tagaactaat gcagataatc
     9721 ctagagatgc tcgtgcagct atagagtttg gtgcagaagg tataggtcta tgtagaactg
     9781 agcatatgtt ctttgatgaa gctagattgc cagcagttag agaaatgata ttatctaata
     9841 cagtagaaca aagagaaaaa gctcttgaaa aaatattacc aatgcaaaga gaagattttg
     9901 tagagttatt taaagttatg gatggaaaac cagttaatat aagattacta gacccaccac
     9961 tacatgaatt tttgcctcat gatgatgaga ctatagaaga actttcaaaa tctatgggaa
    10021 taaaagtaag tgatattaag aagagaatag ttgatttaga tgagtttaac ccaatgcttg
    10081 gacacagagg ttgtagactt gcaataactt atcctgaaat atgtgtaatg caatctaaag
    10141 ctataataca aggtgctata gaagcaatca aagcaggtgt taaagtttct ccagagataa
    10201 tggttccatt agttggagaa gtaaatgagt taaaaataat aagaaaaatg atagtagaaa
    10261 ctgttgacgc tataataaaa gaagaaggta tagaagttcc ttatactgta ggtactatga
    10321 tagaaatacc tagagcttgt ttaactgctg atgaaatagc acaagaagca gacttcttca
    10381 gttttggtac taatgactta actcaaatgg catttggata ttcaagagat gatgctggta
    10441 aattcttagg tcaatatgta gatgaagaaa tattagaaaa agacccattc caagtactag
    10501 accaaaatgg tgttggtaag ttagttaaga tgggagctaa attaggtaga gaagttaaac
    10561 cagaattaaa actaggaata tgtggagagc atggaggaga accatcttca gtagagttct
    10621 gttatagtgt aggacttaac tatgtatctt gttcaccatt tagagtgcca attgctagac
    10681 ttgcagcagc tcaagcatct ataaaaaatc ctagataata atagactgca aaatatgtaa
    10741 ctaaataaaa ataaaatccc ctattgttca atgtatcaaa ttaagtattt gtaaattgaa
    10801 tataggggat ttttattata aaaatttaac ttatacagtt gtaagtgaaa cgtatttaat
    10861 tatattgcat atattattgt agagagaaat ttcaactatc aattaaattg agtttactgg
    10921 aggggataaa gttgacaaag tgtcctaaat gtggaaagga agtatcatca cgtccaggta
    10981 gtatatgccc acgatgtgga tttaaagtag cagatgagag tctaaaaata agatgtccag
    11041 aacctagttg tagggctttg gtatctagga aactggatta ttgtcctaaa tgtggatgca
    11101 aacttagagg atataatatt tctgaatttg ttaacatggt aagatgtaaa atagatgaga
    11161 catttgataa aaaataatta aatttagagt taagcttttg agggtgtctc aaaatgaact
    11221 ttttagttca gaaggcactc tttttgtatg gaatcaaata tatttttata atttaaacaa
    11281 taaaaaagag gcttatctct attttagtat aatcccctta tagtagacat ttaaataaaa
    11341 ggctattata ataagtctaa aaagcgtata ctctaagggg gtttttctat gtctaaaaaa
    11401 cataaaaaat atagcaaaga acttaaacta aaagctgtaa atttatatat aaaagaagga
    11461 tactcatcat acaaaattgc tgagatgctg aatataagaa gc
//
LOCUS       DAMJWO010000104        11498 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.107, whole genome shotgun sequence.
ACCESSION   DAMJWO010000104 DAMJWO010000000
VERSION     DAMJWO010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11498
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.107"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(72..497)
                     /locus_tag="PC366_003248"
                     /pseudo
     CDS             complement(72..497)
                     /locus_tag="PC366_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
     gene            complement(970..1257)
                     /locus_tag="PC366_003249"
     CDS             complement(970..1257)
                     /locus_tag="PC366_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578737.1"
                     /translation="MRLNVTKQNTIEVENSRKEDVYFVIVDNVFFERQGDVFNSITNN
                     NLNNYDVKILPTDNVFLELKITSTKDLEPVFIVVEDRQYNHGSIMFKPVLV"
     gene            complement(1277..1552)
                     /locus_tag="PC366_003250"
     CDS             complement(1277..1552)
                     /locus_tag="PC366_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578738.1"
                     /translation="MSLFVGGWSKFRAVEEEDLKVFNEAIGMLKGVDYEPLIVATQVV
                     AGTNFKFICNATSVTNPPHDYLAEIIVFKPLPCDEHNATITSINIIK"
     gene            1740..2559
                     /locus_tag="PC366_003251"
                     /pseudo
     CDS             1740..2559
                     /locus_tag="PC366_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418025.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            complement(2818..5385)
                     /locus_tag="PC366_003252"
     CDS             complement(2818..5385)
                     /locus_tag="PC366_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HDF2578739.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQIFVETNHIQSRINKLLDGIDSNNTNQLEDVSKKIGELFHNGEMPQEVSDAIKTAY
                     AGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDAVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSKP
                     LLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMDGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIALQSEKE
                     LWGLSEWVKQNNSINLYLQNSPAIKIAEDFMSSVMPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAYSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAELKKYMGYVSPSKLPEKNKKTISQ
                     APQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKSGQMITVDGLAGTVTFDE"
     gene            complement(5388..5993)
                     /locus_tag="PC366_003253"
     CDS             complement(5388..5993)
                     /locus_tag="PC366_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2578740.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDGEPSPQQCLRKIMLNHLRFP
                     EQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRPSDSSEKMLDETMNIFLHGIMNDGGE"
     gene            complement(6367..7827)
                     /locus_tag="PC366_003254"
     CDS             complement(6367..7827)
                     /locus_tag="PC366_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HDF2578741.1"
                     /translation="MFNELKTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEVIKNTKESIKVWAEMPVYKRANIFHKAADLLLENIDEIANILVLEIAKD
                     IKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGVLNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVGKIKPLVEKLTIGNPMDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLITGNVRKNNLFYPTLLDNVNVDMKIAWEEPFGPVL
                     PIIRVKDINQAIEIANQSEYGLQSSVFTSDIDRAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVREL"
     gene            8158..8736
                     /locus_tag="PC366_003255"
     CDS             8158..8736
                     /locus_tag="PC366_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2578742.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGSFYTFFDSKEKLFFEVLNGIQNRLISSVDEILSNMPPKEGFAKSLKMLYRLYDKN
                     PFLYSPNNPDFISLINKLPQDMFLQLESNNIQSFYDLIKRHNLKLKIEKEKAFGVCNS
                     LLSSLLVKENIEYNYIEVFDFMVDNLVEHILE"
     gene            9028..10278
                     /locus_tag="PC366_003256"
     CDS             9028..10278
                     /locus_tag="PC366_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2578743.1"
                     /translation="MVKSSNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIVFSPIGGAIADIFNRRNLMVIFDFSSSLTVLILAVFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQNSNIIKTIFTDIKDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKHLKITNLHISFIICAVMFIPMAVSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYVITVTQLKTPNELLGKVMSILFAGTAIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLLIAFVSKITLRNENL"
     gene            10439..11008
                     /locus_tag="PC366_003257"
     CDS             10439..11008
                     /locus_tag="PC366_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDF2578744.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVDFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAVAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
BASE COUNT         3802 a         1994 c         1588 g         4114 t
ORIGIN      
        1 gtttccctat atgctgacta ttttagctac taactcatga ctaaattcac gagtgtgcgt
       61 agctattttt taatcaatac aattactgca catatagatg cagaattttt aaatacttca
      121 cctaatgaaa ctgctgcact aatatcatgg gctactcccc tattgtcgct aaaacctgca
      181 gtatcacata attttgcatc cattccttct attggttttc tcatatttac aatgtttggg
      241 tataaagttt gagaaacagc tcctgaacca atctctgcca cagggtctaa gcaatcaata
      301 tatgatatac cagtatcttc atcttctact tccatcatta cacatcctgc aagatagtta
      361 attgcagtac ttttgccaca tcctgtccca ccaagaatta gaattaaatt ttgattttca
      421 gccttattta ttgctacttt tccttcattt aataagagtg ttatttcttc taaaagttga
      481 ttgttatttt ctggcattta ttttccccct tggttatata ttttatttaa ataaagttta
      541 atcccttaag tagattacaa agtttttaga ctatatttaa atttgttttt tatttttaat
      601 aaatttgcat tttcactcaa taattattct tctttgttta ttaaaataac tgtgttgtat
      661 aatataattt ttaccaacac agttatttta tttaatgcgc ttattttatt gtattttatg
      721 taatacagtt gtttttttat attatatgtc cactattttc ctatggttat tacatataga
      781 tttttaatta tatttgtacc attaatttaa acattcctat actactgctt aagttttaca
      841 cctataccag cttgaatatt ttatttttat ttgcttaaat agttcaacta tactggttta
      901 ataggtttcc tttagtttaa atagttcacc tatacctact tgaatagttc acttttattt
      961 gcttaaattc tataccaata ctggcttaaa cattatacta ccatgattgt attgtctatc
     1021 ttcaactaca ataaaaacag gttctaaatc tttagtagat gttattttta attctaaaaa
     1081 aacattatca gttggtaata tttttacatc ataattattt aaattattat tcgtgatact
     1141 attaaataca tcaccttgac gttcaaaaaa aacattatca actattacaa aataaacatc
     1201 ttcttttcta ctattttcaa cctctatagt attttgttta gttacattta gtctcatctt
     1261 ccacctccta ttaatattac ttaattatat taatacttgt aattgttgca ttatgttcat
     1321 cacaaggaag aggtttaaaa acaattatct ctgctaaata atcatgtgga ggatttgtaa
     1381 ctgaagtagc attgcaaata aatttaaaat ttgttcctgc tacaacttga gtagcaacaa
     1441 taagtggttc ataatcaacc ccttttagca ttcctatagc ttcattaaat acttttaaat
     1501 cttcttcttc gacagcccta aattttgacc atccaccaac aaaaagactc atataaaaac
     1561 ctcctttata tatatattta tttatatgat agtaccaatt ttcttaatat tcaatatatt
     1621 acgtctaact ggtcaataaa aatgcataac tggataaaaa gacttataaa atagcttaac
     1681 tttacatata ataagattat tctaaaatat gagacatatc ttgctttgaa tatattctat
     1741 acaacaattt tccaggcctc attgccaagt ttaaggtaac tgactttgga ttccaacttc
     1801 ttgatgctaa taaaaaatat tttgatatgt tcaaagataa tgtaaatttt ctattagatg
     1861 atataaattt agaaggttat cttaacaatg tgtataaata tcataatgat tttaaatctg
     1921 ggagatgcgt ttgtttttct atttctccac aaactattaa tggagatatt tttcacatgc
     1981 aagttgtagc tgaatgtata gattgggaag atgataagcc tatatatctt ttaatatatt
     2041 cagatgtaac gacattggta aaacaatatg tctcattatc atttttcatc caagaatttt
     2101 atcaagaaat atgataaaat agctaaaaaa tatgatattc cttctcacct tatagaaatt
     2161 gagattacag aaacaattgt atttgaagat gtcaaagtat ttagtgaaat aataaatgaa
     2221 attcataaaa atgactttaa atgctctatt gatgattttg gaagtggcta ttcttcaatc
     2281 aatatgctta agggtattta tgttgataca ttaaaattag atagagcatt ttttcaatca
     2341 gaagatttag attctcaacg tgaaagaaat ataattgtat ctataatcga actagctaaa
     2401 aagttaaaaa tgaccactgt agctgagaga atagagacca gttttcaaaa agatttcttg
     2461 caagaaataa actgtgatat gttacaagga tacgtgttct ctagaccttt gcaaataaaa
     2521 gactttgaaa aacttatgtt tcaaaactcc tccaattaac aatataaaat tgcttattat
     2581 aagtgtatta ttgtatcaac aaataaagga attgtctcaa aattgatttt ttctaatcaa
     2641 atttttattt tgagacattc tcattttttt gcataagaaa atacccacca agctacggtt
     2701 tttcttaccg ctgttcggtg ggtattagta gtattatgaa atctgaaaac tttaagtatt
     2761 actacttccg ctaacgcaat cacaaaggtc gaaagcttca aagcgaaaat aggcttttta
     2821 ctcatcaaac gtcaccgtac ctgccaaccc gtccaccgtt atcatttgtc cgctcttaat
     2881 agttcgtgtg gcaatgtgtg tagccataac ggctgggatg ccatattcac gtgcgacaat
     2941 gcttgaatgg ctaagaggac caccaatgtc cgttacaatc gcacttgcag atgaaaataa
     3001 tggtgtccat gctggagttg tggtaactgc aaccaaaaca cttccaggtt gaaagctttc
     3061 aaaatctgct ggactattca gtacacaagc tggagccgtc acaacaccag tactggtacc
     3121 aatgcccgtc aacacaattt tcccatcttt ctgcttctgt ggtgcttgtg atatagtttt
     3181 tttgtttttc tctggcaact tggacggtga cacataaccc atgtattttt taagttcagc
     3241 ttttcgaaca ggtattatcc cgttcatatc agatagagac ttgtttttat ccaactgctc
     3301 tataagtacc tccaattccg attttgtgag ccaataaata tcatctaaat gtgaaatagc
     3361 tcctcctcgt atgaatcgtt ctgagatttc ctgaaacata caacgaatca gaggatgtcc
     3421 cattcccatc aaataaatag cattttcacg cataggagag gtttcctgtg cccaatggag
     3481 caacttaaaa aatagttttt tacgcaatcc acctatgtgt tgtaaaatct cttcttctgc
     3541 atgttttcta cgcttttcaa acgtggtctg gcgtaaaaaa ggactttccc cttttccttc
     3601 cacaaatgtt tttacggatt caaaagttgg tgtaagtgtt tcctgcggtg tggaatacgc
     3661 aaaatcaaac tcataagcgg tacgaccaaa ctctttaaag tacttattga ttcgattttt
     3721 ccattctatc catacttcct gtgaaactcc aacaggcata actgaagaca tgaaatcttc
     3781 tgctatcttt attgcaggac tgttttgcag ataaaggttg atgctgttat tttgctttac
     3841 ccattctgaa agaccccaca actccttttc cgattgcaga gcaatcgtat caaacccaag
     3901 caggaaaacg gaagtatccg ttataccagc acgtcgaact gctccttgaa ataattttgt
     3961 aaataatgtt tcactgatag aagcagcagg caatgtaagc tgaatccttg tgaaataaat
     4021 acatgcggca taaaatattg tctgaatacc atccataatt tgatgggcgt tcatcgtatg
     4081 caggggcttt tcttcccatt gtttaatagc atcctcatat ccttttcgtg ccgtttccca
     4141 gcgtgcaacg ctgttcataa gtgtcctacg taaagagcgt ggggaaaggg atttgatagc
     4201 aatcaaaagt ggctttgatt tagcagaaag ataaacatat ccattaataa ccgtatatgc
     4261 gccgtttttt ggtaataatt ttttcgcact tttaccaaac atatctatcc ataaaagctc
     4321 cgatgcacgg tttacgattt caagaccaag cgtggcgaac aaaggtgtaa caggatttgg
     4381 caagtgttct gccaaacttc cctttgtgta tacaacatcc tgttctggca atacccattc
     4441 cggtggcaga acagtaattg gacgagcttg aacaatgtac aatttatctt tttccagtgc
     4501 ccactctaca tccataggca tttgataata cttctcaatt ttctttccaa gctgtatcag
     4561 ttgcattacc tgattacgag taagagcata tttttttctc aacctttcag gaaccatggt
     4621 ttcttctgtt ccttctgaag tacgaaccgt cataatctct ttatttgcca cttcatacga
     4681 tataattcgt tcggagtcct tatccactac gattgtatcg ggtgtaacta agctagaaac
     4741 caccgcttca ccaagccccc atgcagcgtt aataatcatt tcgctacgtc taccattgat
     4801 tgggtttaac gtaaacataa taccagatga atcggaaaat gcaagctttt gtactacaac
     4861 agcaagtgcg acaatctcgt gctttatatt attcttcaca cgataagcaa tagcacgagc
     4921 tgtccataag gaagcccagc atctctttac agcgtcaata actttatctt caccttgtat
     4981 gttaagataa gtttcctgct gacctgcaaa agaagcgtca ggtaaatctt cagcagtcgc
     5041 agacgaacga acagccaccg atatgttccc taatccggca taagctgttt taattgcgtc
     5101 cgacacttcc tgtggcattt ctccattatg gaaaagctcc cctattttct tagatacatc
     5161 ttcaagttgg ttggtattat tggaatcaat accatctagc agtttattaa ttcgagactg
     5221 aatatggttc gtctcaacaa aaatctggta tgaagcagtc gtaacatgaa aaccgtctgg
     5281 cacagggatg cctgctgtca atagttttga taaagacatc ccttttccac caacaatttc
     5341 aatggttgct tgtttatgtt ccagtggcaa gacataataa atcataatca ttcacctcca
     5401 tcattcataa ttccgtgcag aaatatattc attgtttcat ccaacatttt ttccgaacta
     5461 tccgatggtc gtgacgtgta gctgattgat aacatggagt taattaacaa acgtgtcaca
     5521 agagcggtat ccgttttgcg aaagatgcct gtggtcacac cattatcaat taccgatttt
     5581 ataatatctt gatatgcata acgagcatct ttaagtctct ttcgatactc ttcttctaaa
     5641 taatcagatt ctgtatttaa ccacatcagt acagttctat actgctctgg aaatctaaga
     5701 tgattaagca tgatttttct aaggcactgt tgtggtgaag gttcaccatc aataatccta
     5761 tgaacttgtt ggatagtttt ttctatttct ttctcaactg catatacaac aatctcgtct
     5821 ttcgttttga aaaaatcgta tagacttgac tttcccatgt tggctaaaac tgcaatttct
     5881 ctcattgatg ttttttggaa tccattttca gccatgagac tcaaagcaac agcaactatt
     5941 ttttctcggc gttctgcttg ttgttcaggt gtaagcacaa ttccttttgg catagggcga
     6001 tacctccttt tagcgaccaa tggtcgtttc ttttttattt atcatacagc gaccatcggt
     6061 cacttgtcaa ggttaatttt tttcattgta tatggtactc gagataaaaa tgttcatttt
     6121 agaaattgct ctatttaagt agaaataggc ttcatcatta gaaaacaaga ctataaattt
     6181 gagatattta tcatgttcaa atttcatcaa tatcaaagtt taagatatta ataaaaaaag
     6241 aattactaag aaataacata taaagattca aaaaaggagt tgaacttaaa attcaattac
     6301 aaaaaatcaa atttaagaca actcctttat tctttatctc tactattctt tatctctatt
     6361 tatttattac aactccctaa catttaccac tactgcctta ggtctagtca tagcctcgat
     6421 tgaatactta acaccttgag ttcccatacc agatgccttt acacctaaaa atgggaagtg
     6481 gtctggacct ctttcagtct tattatttat ttgaacagta ccaacttcaa gtttatcagc
     6541 tatataaaat gccctatcaa tatcacttgt aaatactgat gattgaagcc catactctga
     6601 ttgattagca atttcaattg cttgatttat atctttaact cttataattg gaagtactgg
     6661 accaaatggt tcttcccaag caattttcat atcaacattt acattatcta acaatgttgg
     6721 atagaataaa ttattttttc taacattacc tgttattaac tttgctcctt tatgtaatgc
     6781 atcatcaacc aacccttgaa caaaatcagt tgctttatta tctataagag gagtgataac
     6841 tacttcatcc attggatttc caattgtcaa cttctctacc aatggcttta tttttccgac
     6901 taatttatcc gccacactct cttgtactaa aattctcttt actgccgtac atctttgtcc
     6961 tgaatatgaa tacgctccag atactatatt cttagctgca aaatctaagt ctgcatcttc
     7021 taatactata gccgcatctt ttccaccaag ctccaataat agtggtacca ttccagatat
     7081 tttagatata tgctgaccaa cttcagtact accagtaaag ttaataaaat taattccttt
     7141 atgcgttaca acataatccc ctatctcact acccctacct gtaatagtat taagtactcc
     7201 atctggtatc ccagcttttc tcatgatttc taccacatga agtgcgctaa tagccccttg
     7261 tgtagcaggt tttaatacaa ctgcatttcc accaataagc gctggagcaa tctttgacat
     7321 tgataaattt acaggataat taaaaggaga tatagctaaa acagtaccta atggaaccct
     7381 tgaaacataa gacatcttat ttcttgttcc accagggaaa ttatctccac taatggcttc
     7441 accctccata ttttttccca catcagctgt gtatcttaaa aaatctgctg ttctctcaac
     7501 ttctgccctt gcagatttta tgtctttggc tatttcaagt accagtatat tagctatctc
     7561 atctatattt tctaacaata aatcagcagc cttatgaaat atattggctc tcttgtatac
     7621 aggcatttca gcccatactt ttatactctc ttttgtgttt tttataacct catctacctc
     7681 atgttttgtc atagattgta ctttcccaac aagagaatta tctattggtg agtaaatttc
     7741 tattggcttt ctcgaattag attctaccca ttttccattt attaaatttt tatatacatt
     7801 ttcttttgtt ttaagttcat taaacatatt tttattcctc tctctgatat aactttgtgt
     7861 atttaaatta tagccattta ttcgttatgt aaacatttct ttttttcata aacgtttacc
     7921 tataaaaaaa attttaagtt aacgtttttc tagattcttc tattttaata acatactcgc
     7981 tccaaatcta tataggtcac actttaatat caatatacca atataccaat ataccaatat
     8041 aaatattata aacataaatc acttgacaaa tttataagta gacaatatta tatatctatg
     8101 acttaaaata tttttaaagt catagatagc atatgcagat agaaaggatt gataaaaatg
     8161 gctaaaagtt ttacagaaat agaaaaagac aatataagaa aaagactaat ttcagaatgt
     8221 gaaatcaact ggtctaaata tggatacaaa aaaactaaca ttgatgaact ttgttcaaaa
     8281 tcaggaatcg caaagggttc tttctataca ttttttgatt caaaagaaaa gttatttttt
     8341 gaagtactaa atggaatcca aaacagactt atatcatcag tagatgaaat tttaagtaac
     8401 atgcctccaa aagaaggctt tgcaaaatcc ttaaaaatgt tatatcgatt atatgataaa
     8461 aatccatttt tatattcacc aaataatcct gatttcatca gcctaataaa taaactacct
     8521 caagatatgt ttttacaact tgagtccaat aacatacaaa gtttttacga cttaattaag
     8581 agacacaatc tcaagttgaa gatagaaaaa gaaaaagcct ttggtgtttg taattctcta
     8641 ctatcaagtc tattggtaaa agaaaatatt gaatataact atattgaagt atttgatttt
     8701 atggtagata atcttgtaga acacatactt gaataacaat ttaaaataat ttttctaaat
     8761 atttctttat actaaagagg attaatatga ttgaattaat gaaaaaaata aacaatatca
     8821 tttacaaaat aaatgataaa ctaaatatac acacaaaact tatagacccc agagttaact
     8881 cattccactc tactctaagc catctataat agttcgtata tttctaataa tattagatat
     8941 taaagtaaga aaaaaattcc ttataataat tgctattata tcaattatta taaatatttt
     9001 aataatctta gataggtagg tatatatatg gtaaaatcct caaacacttt taataaaaac
     9061 ttcaacttga tgatattagg tcaaataatc tcattgtttg gtgcatcaat acttaaattt
     9121 gctttatctt tatacatact tgatataact ggtaaagcag aaatatttgc tactatacta
     9181 gcagtatctt caatcccaat tatagtattc tcccctattg gtggagctat tgcggatata
     9241 ttcaacagaa gaaacttaat ggttattttt gatttttcaa gcagtcttac agtactaatc
     9301 ttagcagtat tcttattcaa caataatggt tcaatattac ttgtaggaat tattatgacc
     9361 atattatcag ttataagcac aatgtatcaa ccaactgttc agtcaagtac acccctttta
     9421 gttgataatg agcatttaat gaatgcaaat ggtattgtag ctggagttgc atctcttaca
     9481 aatattgcag gacctgtatt aggaggtgtc ttgtatggtg tgattggaat taatgcaatt
     9541 atagttataa gttgtgtaag tttctttcta tctgcaatta tggagatatt tatacagatt
     9601 ccttttatca aacaagagca aaacagcaac attataaaaa ctatatttac tgatataaag
     9661 gatggtattg ttcatatatg taaagaaaat agatttatac taaaaatact ttttttagct
     9721 atagcaataa acttattttt aagctctatg ttaatagttg gtatccccta tatagtaaaa
     9781 atcactatgg gagctagtaa cttcttatat ggtctagcag aaggagcaat ttcttttagt
     9841 tcactggtag ctgctgttag tattggtatt ttctcaaaac atctaaaaat cactaatttg
     9901 cacatttcct ttattatatg tgcagttatg ttcataccaa tggcggtttc agtatatcca
     9961 tttatattaa acacaggatt tccagttcca tttttaatct ttatagtatc atctatgcta
    10021 atatttttta caacgactct tatctcaata tatgttataa cagtcacaca attaaaaact
    10081 ccaaatgaac tcttaggaaa agtaatgtca attctttttg caggaacagc aattgcaatg
    10141 cctcttggtc aggttatgta tggtaaactt tttgatttat tatcagatag agtgtacatc
    10201 attatactag gagttggatt tattacacta cttatagcat ttgtatcaaa gataacattg
    10261 aggaacgaaa atctttagat acaaagaatt tagatataaa gatttaattt tcactaattt
    10321 ctgaatttaa atgcaaaatt gcgtatcagt atgttgacgt tttagaaatt gattgatata
    10381 atcaatggaa aataaacttt ataaaaattc aaaatattca gctagaggag tgataaaaat
    10441 gagttacatg ccaactttag aacaagcatg ggaaatatta agaaaataca ataaggaaga
    10501 atttcatata agacatgctc aaattgtatc tggagttatg agatactatg caaaggagta
    10561 cgaccctgag agagtagact tttgggaaat agttggactt ttacatgatt tagattttga
    10621 aatgtatcct gatgaacatt gtgttaaaca aagagaatta atgacagagc ttgatttaga
    10681 taaatcaata atcgattcta caataagtca tggatatgga ttaactggtt cagatgttaa
    10741 accagagcaa tttatggaga aagtattatt tgctgtggat gaacttactg gtttaattgg
    10801 tgctgttgca ataatgcgtc cttcaaagag cgtttctgat ttagaattaa aatctgttaa
    10861 gaagaaattt aaagataaat catttgctgc tggctgttct cgagacgtta taagaagtgg
    10921 tgcagaaatg cttggatggg aacttgataa gcttatccaa acaactatag aagctatgag
    10981 aagcttgatt ccagagatgg caatatagct cctcatacat ataccataga agttacatct
    11041 ttaaagagca tttctctttt tgatgcaact tctttttata ttttgtagaa taaaaagttt
    11101 aatattttaa actcactata taatctataa taaatactat aaataatata atgtataata
    11161 gtcataaact ttctaacctt aaaagtttct aatactcaat aaacaattct aatatacaag
    11221 tggcattata tgatttaatt atatatcttc aatttatata ttaaaataaa tatatatatt
    11281 aaattcttat acaccaaatt tttacattaa acttctatgc accacattta tacatattaa
    11341 attcttatat attaaatttc tatgcatcac ttttatacat attaaattcc tatatattaa
    11401 acttttatgc gtcactttta tacatattaa attcctatat attaaacttt tatgcatcac
    11461 ttttatacat attaaattct tatatattaa acttttat
//
LOCUS       DAMJWO010000105        11040 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.108, whole genome shotgun sequence.
ACCESSION   DAMJWO010000105 DAMJWO010000000
VERSION     DAMJWO010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11040
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.108"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            165..929
                     /locus_tag="PC366_003258"
     CDS             165..929
                     /locus_tag="PC366_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaP domain-containing protein"
                     /protein_id="HDF2578745.1"
                     /translation="MQIIDININNIDSRHICCSISEKKGENCVFSKKAWMKNNFDKGL
                     AFKRFDVRGKAFIEYIPAENAWCPITADNYIFINCFWISGKFKGQGYSNLLLQECVDD
                     AKSKGKYGLVVLSSSKKMPFLSDAKYLKYKGFCLADTSEPNYELLYFPFTDNAPIPCF
                     KNCVKKRKLNENGIVLYYSNQCPHTEKYAPILKKIANSRGIDVNLIKFETAKEAQNAP
                     APFTTYSLFFNGEFVTNEILSEKKIEKFLDTNIKKI"
     misc_binding    1152..1365
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1619..2653
                     /locus_tag="PC366_003259"
     CDS             1619..2653
                     /locus_tag="PC366_003259"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HDF2578746.1"
                     /translation="MNKIKVGIIGATGYVGAELIRLLMNHDKVEVTAIGSNSYVGKNI
                     VDIYPSIGYKNNMICIENEKVIDMCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKEDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKNNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCKEKVSVVFTPNLIPVNRGILSTIYCTKEDNISINDIHRKLTDYYEFKEFIEVL
                     PLDKVASLKNVRFSNKCVISLHENGDTLIICSAIDNMIKGAAGQAIQNMNIIFGIEEN
                     TGLKNIAPSF"
     gene            2695..3912
                     /gene="argJ"
                     /locus_tag="PC366_003260"
     CDS             2695..3912
                     /gene="argJ"
                     /locus_tag="PC366_003260"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HDF2578747.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     NIKENDVLVASTGVIGKPLNINLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEEHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            3927..4787
                     /gene="argB"
                     /locus_tag="PC366_003261"
     CDS             3927..4787
                     /gene="argB"
                     /locus_tag="PC366_003261"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HDF2578748.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGMDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFEEGIITGGMIPKIEGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKENE"
     gene            4817..6004
                     /locus_tag="PC366_003262"
     CDS             4817..6004
                     /locus_tag="PC366_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HDF2578749.1"
                     /translation="MNNNNTISKWNEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYSGEKIINSSGMAKVYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYIERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLEIVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVVLKTKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYKEIDEALEILKDILL
                     EIN"
     gene            6113..7135
                     /gene="argF"
                     /locus_tag="PC366_003263"
     CDS             6113..7135
                     /gene="argF"
                     /locus_tag="PC366_003263"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HDF2578750.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAYVTYLGPNDCHMGKKESVSDTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGDIMLTE
                     NIDDVKGADVIYTDVWVSMGEEEQYEARINQLKDYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQKIYEKFGLSELEVTNEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLI"
     gene            7262..7879
                     /locus_tag="PC366_003264"
     CDS             7262..7879
                     /locus_tag="PC366_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HDF2578751.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTIDSFFNSAKKFDFEGM
                     NKVMENNDEKYKDILKELDTKDPNAQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMIGMSFSGQDLTDEKTTEMLVSIMKEKQKSVKETYVTK
                     TVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSMNTLE"
     gene            complement(8099..8797)
                     /locus_tag="PC366_003265"
     CDS             complement(8099..8797)
                     /locus_tag="PC366_003265"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HDF2578752.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSLPTPFYIDRPINHELMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKESINI
                     PILNIVEETVKKLPTISQKVTLFSTSSTFESTIYQNGIIHNGHEFIFKDEWQIKLNNL
                     IQNIKMDKENPHNIDIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDSSKC
                     LAESVVNKYLKLVK"
     gene            complement(8959..10176)
                     /locus_tag="PC366_003266"
     CDS             complement(8959..10176)
                     /locus_tag="PC366_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HDF2578753.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWME
                     GLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNRSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TKFGFNTKNLTNLHPRKDVDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTADLVATVGKMNFYPSSSNVVPERA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDNLDLK"
     gene            complement(10367..10780)
                     /locus_tag="PC366_003267"
     CDS             complement(10367..10780)
                     /locus_tag="PC366_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2578754.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKTEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYYRKIL"
BASE COUNT         4341 a         1201 c         1821 g         3677 t
ORIGIN      
        1 aatgtattta attatatatg caatttgata attcaaataa tctaaaaata atattatgta
       61 aaataaaaat atatatgaca tgatgttgtt gtattcaaaa tattaagata aaaatatata
      121 gaatatattt aaaaattatt atgtaattag aaaaggagat aagtatgcag attatagata
      181 taaatataaa taatattgac agtagacata tatgctgttc aatttctgaa aaaaaaggag
      241 aaaattgtgt tttttctaaa aaagcttgga tgaaaaataa ttttgataaa ggtctagcct
      301 ttaaacgatt tgatgtaaga ggtaaagctt ttatagaata tattccagca gaaaatgcat
      361 ggtgtcctat tactgcggac aattatatat ttattaactg tttttggata tctggaaaat
      421 ttaagggtca aggatattct aatctattgc tacaagagtg tgttgatgat gcaaaatcaa
      481 aaggtaaata tggattagtt gtgctttcgt ctagtaaaaa aatgcctttt ttatctgatg
      541 ctaaatatct aaaatataag ggcttttgtt tagcagatac atcagaacca aattatgagc
      601 tattatattt tccctttact gataatgctc ctattccatg ttttaagaat tgtgtaaaaa
      661 aaagaaaatt aaatgagaac ggtatagttt tatattacag taatcagtgt ccacatacag
      721 aaaaatatgc tcctattttg aaaaaaattg caaattctag aggtattgat gtaaatctta
      781 taaaattcga aacagcaaaa gaagcacaaa atgctcctgc accatttact acatacagtc
      841 ttttttttaa tggtgaattt gtaaccaacg agatactttc tgagaaaaag attgagaaat
      901 ttttagatac caacattaaa aaaatttaac taaaaataga tgtaaatatt gtattttgag
      961 attacattat tttataatcc aatatatttt ggaaatttct taagttgatg aatgataata
     1021 taaagattat aactcaattt agatacaaaa tgctggaaat taaccatata gaaaatattt
     1081 ccaaaaattt aaaaattata ttgacaaagt taaaaaaata aactatcata taaaacaata
     1141 agaaaataaa ttgaaatcct gtgaaaaaga gagtagcata aagctagttg atagagagct
     1201 gggaatggtg gaagcctagt aacgaatttt attgtgaata gagctttgga ggagattacc
     1261 agaagtaata gtatggtaat tggtgaatct cgccttaaga gattagagtg ggtaagatta
     1321 tcttatcaat tagagtggta acgcgggtgt atattcgtct cttggtcttt gaccaagagg
     1381 cttttttaat tttaaatgta cattttgtag atacttttta atttgagttt taatgattat
     1441 tgtaatttta ccaatgagag tggtaccgcg gaaaatcgcc tcttagtatt tataatgcta
     1501 aggggttttt tgttttaatt agaatatttt aatctacata ttatcaaatg attatcatat
     1561 agtaaagtgg aaagatagaa ttttaatact atttgaatat aaaaatggag ggaacaaaat
     1621 gaataaaata aaagttggta ttattggcgc aactggatat gtcggggcag agttgattag
     1681 attattaatg aatcatgata aagtcgaagt gacagcaata ggttcaaatt cgtatgttgg
     1741 aaaaaatata gttgatatat atccaagtat aggatataaa aataacatga tatgtataga
     1801 aaatgaaaaa gttatagata tgtgtgatgt tgtgtttaca gcccttccac atggagttag
     1861 tgaaaagttt gtaataaaag caattaaatc gaaaaagaaa gttatagatt taggtgctga
     1921 ctttagaata aaagatgaag aagtatatag taaatggtat ggagtatctt ttatagataa
     1981 aatcttacat aaaaaagctg tatatggatt aagtgaaata tacaaagaag atataaaaga
     2041 tgcagatata attgcaaatc ctggatgtta tccaactagt atttctttac cattgatgcc
     2101 attactaagt tctaaattga taaaaaataa taatataata attgattcta aatcaggtct
     2161 tacaggtgct ggtagagaat tatcgattag tagtcacttt acggaggtta atgaaaatat
     2221 cactgcatat aaaataggga aacacagaca tactccagaa atagaacaaa atttaagtga
     2281 atcctgcaaa gaaaaagtaa gtgtagtttt tacaccaaac ttaataccag taaatagggg
     2341 aatcttatca actatatatt gtacaaaaga agataatatt tctataaatg atatacatag
     2401 aaaattaact gattattatg aatttaaaga atttatagaa gttctcccat tagataaggt
     2461 agcttcttta aagaatgtta ggttctcaaa taaatgtgtc atatcattac atgaaaatgg
     2521 agatacattg ataatctgtt cagctataga taatatgatt aagggagcag caggtcaagc
     2581 tatacaaaac atgaatataa tatttggtat tgaagaaaat acaggtttaa aaaatattgc
     2641 accatcattt tagtaatgaa aaaatactaa actcatataa ttaggaggat aaatatggag
     2701 attataaagg gtggagttac agtttcagaa ggattttttg cttcagggat tcactgtggc
     2761 ttgagaaaaa ataaagaaaa aagagattta gctttggttt attcagatgt tttatgtgat
     2821 gcagcagcag tagtaactca aaataaagta aagggcaatc ctgtttatgt tacacaggaa
     2881 cacattaaaa atggaaaagc acaagctatc atagtaaata gtgctaatgc taataccttt
     2941 aatggaaaag aaggacttat aaatgcttat aaaatggcta aattcactag tgataaatta
     3001 aatattaaag aaaatgatgt tttggttgca tctacaggtg tcataggaaa gccattaaat
     3061 ataaatttaa tagaagaaaa tatggatgaa ttagtgaata atctaagtaa acaaggtcat
     3121 attggagcaa gagaagctat tatgacaact gatattataa aaaaagaaat agcagtagca
     3181 ataatgtatg gagataaaaa aataactatt ggaggtatgg caaaaggttc tggcatgata
     3241 catcctaata tggcaacaac gttaggattt ataactacag atgcaaatat tgatggagtt
     3301 ttgctaaaag aagctttgaa aattgctgtt gataaaagtt ttaatagagt tagtgtagat
     3361 ggagatacaa gtactaatga tatggtgatg attctagcaa atggaaaagc aaaaaatgat
     3421 agaataaaca aaaaagatga acattatcaa gtatttttga gtgcacttac atatgtctgt
     3481 atagaacttg ctaaacttgt tgcaaaagat ggagaaggat gtacaaaact aattgaatgt
     3541 tatataaatg gagcattaag tgaagaacat gcagtaaaat tagcaaaaac agttatatct
     3601 tcttcattag taaagacagc tgtatttgga gctgacgcaa attggggtag aatactgtgt
     3661 gctttaggtt atgcaggtga agaaatagat atggaaaaag ttgatattat ttttgagagt
     3721 atgaaaggat atattgaagt atgtaaaaat ggaaatggat tagattttaa tgaggaaaaa
     3781 gcaaaaaaaa tccttgaaga tgacgaaata agtatattag tagatttaaa tatgggcaat
     3841 gccagaggaa atgcatgggg atgtgattta agctatgatt atgtaagaat aaatggaagt
     3901 tatagaaatt aggaggatat actttaatga ttaatataga aaaagcaaat acacttatag
     3961 aagctttacc atatatagaa aaacatcagg gaaagactat tgtagttaag tatggtggaa
     4021 gtgcaatgaa aaaagatggt ctaaaagaat ctgttatgga agaccttgta ttaatgagtt
     4081 atgttggaat caatatagtt ttagtacatg gtggaggggc agaaatcaat aagatgctag
     4141 caaaagtgga tatagaaagt aaatttgtaa atggtcttag atatacagat gaagagacca
     4201 tggaaattgt aaaaatggta cttgctggaa aggttaataa agacctagta aataaaatac
     4261 atacaaaagg tggaaaagca gtagggcttt gtggaatgga taataatatg attttatgtg
     4321 acccatataa aaattatgaa cttggatttg taggagaaat caaaaaagta aatgttgagc
     4381 ttatagaatc ttgtctaaag tcaggttata tttcagtaat tgcaactata ggtgttggag
     4441 atgatggaga gacttataat ataaatggtg acacagcagc ttctgctata gctaaagagt
     4501 taaatgcaga taaattgata cttcttacag atgtccctgg tttgttaaga gagccagatg
     4561 aagaaaaatc attaataaca gaagttatat tagaggatgt tgataaatta tttgaagaag
     4621 gtataattac tggaggtatg atacctaaaa tagagggatg cgtagatgcc ttaaataacg
     4681 gagtaaatag ggtacatatt ttggatggaa gagttccaca ttctataata acagagctat
     4741 ttactgatag tggaataggt acattaataa gaaaagaaaa tgaataaaat tataagttta
     4801 agaggggaga ataagaatga ataacaacaa tacaatttca aaatggaatg aatattttat
     4861 agatacatat aaccaaccca attttgtcat agattatggt gaaggaagtt gtttttttga
     4921 tactaatggc aataaataca tagattttac aagtggatat ggagtatctt ctcttgggta
     4981 tagtaatagt aatttaaaga atgctctaaa agagcaagta gataaattat tacatacttc
     5041 aaatttatat tttaatgagc cagtgttgta ttcaggagag aaaataatta attcaagtgg
     5101 aatggctaaa gtatattttt gtaattctgg aacagaagca aatgaaacag cattcaaaat
     5161 agcaagaaag tatagtagtg acaaatatgg taatggtaga ggaactatca taagtttaaa
     5221 agactctttt catggtagaa caatgatgtc tttaatggca actggtatgg acaaatacca
     5281 taagtatttt tatcctcttc ccgaaggttt taaatatata gaaagaaata atattgaaga
     5341 tttaaaaaat aatcttgatt ccacagtttg tgcaataatt cttgaagcga ttcaaggcga
     5401 aggtggagtt aatgttcttg aaaaagatta tgttttggaa atagtaaaaa tatgtcaaga
     5461 aaaggatatt gtagtgattt ttgatgaagt ccaatgcggt ataggaagaa ctggtaaact
     5521 ttttggctat gaatattttg atgtaaaacc agatatagtt accgtagcaa aagggttggg
     5581 agcaggaata ccagtaggag gagtattggt aaataaaaaa ctttcaaaag tactaggaaa
     5641 aggagaccaa ggtacaactt ttggaggtaa tttattagct atggtggcag cttcagttgt
     5701 attagatgag atatctaaag atggttttta taatgaagta ttagaaaaag gaaattatat
     5761 aagaaaatct attgaaagtt ttaataataa agttgtatta aagacaaaag gtattggtct
     5821 aatgatagga attgaaacta atattgaatc tagtattata gaagagaaag ctagaaaaaa
     5881 aggattgctt attttgactg ctggaaaaaa tgtattgaga tttttaccac cattaacaat
     5941 cagttataag gaaatagatg aggctcttga aatcctaaaa gatatattac tagagattaa
     6001 ctaaatattc aaaaaatagt taattaaaga taaaaattag aagtaaataa aaaagtaaag
     6061 tgctaacaag tttaattgaa tttaagaagt ttataagaag gggcgaatta atatgaataa
     6121 tataagttta aaaggtaaga gttttttgac attaaaggat tttacaaaag aagagattag
     6181 atatttatta actttatcaa gttatttaaa aactaagaaa aaagttggca taaaaggcga
     6241 tttgctacaa ggaaaaaata tagctttatt atttgagaaa acatcaacaa gaactagatg
     6301 ttcatttgaa gtagcagctc atgatgaagg agcatatgta acttatctag gtccaaatga
     6361 ttgtcatatg ggtaaaaaag agtctgtatc agatacagca aaagttctag gaagattcta
     6421 tgatggaata gaatttagag gctttaaaca agaaacagtt gaaagtctag caaaatattc
     6481 tggtgtacct gtttggaatg gacttacaga tgaatatcat ccaacacaaa tactggcaga
     6541 ttttttaaca gtaattgaaa atgtagataa agatttgaat aaagttaaat ttgtatatgt
     6601 tggtgatgct agaaataata tgggaaactc actgatgata ggatgtgcta aaatgggaat
     6661 acatttcgta gcactagcac ctaaggaact ttggccaaat gaagaattgg ttaaggaaat
     6721 gaaggaaata gccaagaaat ccaaaggaga tataatgttg actgaaaata ttgatgatgt
     6781 taaaggtgca gatgttatat atacagatgt atgggtttct atgggagaag aggagcaata
     6841 tgaagcaaga ataaatcaac ttaaagatta tcaagtaaat atggatatga taaagaaaac
     6901 tgaaaatgaa aatgttatat ttttacactg tcttccagca tttcatgatt tagaaactaa
     6961 ggttgctcag aagatttatg aaaagttcgg attatcagaa ttagaggtta caaacgaggt
     7021 atttaattca aaatattcaa aggtatttga agaagctgaa aatagaatgc atacaataaa
     7081 agctgttatg gtttctacta tgactgatgt aaatatgaac aataatttaa tatagatatg
     7141 ttttaatata gactttactt taatgaaaat ttataaaata ttttaaatat attattcaaa
     7201 aactctcatt atatgttaaa ataacttatg tatcaacaaa ttaagaggga ggatttgaga
     7261 tatgaaaaaa atcatattag ctttaacaac ttttttatta gcaatatctt taacagcatg
     7321 ttcaagtgca aaaccagaag atacaattga tagttttttt aacagtgcga aaaagtttga
     7381 ctttgaaggc atgaataagg taatggaaaa taatgacgaa aaatataagg atatattaaa
     7441 ggaattagat acaaaagacc caaatgccca atatgtttta gattatctaa aacagaatgc
     7501 atctaaaatc acgtatacaa taaaagacag cgaggttaaa ggtgataagg ctacaatcaa
     7561 agtagaatgt aaatttatag attcaacacc attacttcaa gaaatagtag ctgaggcatt
     7621 tacaaagatg attggtatga gtttttcagg acaagactta actgatgaga aaacaactga
     7681 aatgttagta tcaattatga aagaaaaaca aaaaagcgtt aaagagactt atgttacaaa
     7741 aactgtagag tttgaatgtt ctaaaaagga taataaatgg ataataagtt cagtaaatga
     7801 tgcagtagct gatgtattgt tatctaatct tgttacagca ggacaagaat tttctaactc
     7861 tatgaataca cttgaataat attgtttagg tgtagtaaag taataaatat atgattattt
     7921 ttataaataa acatataaat atttatgaag gataccattt ttggtatcct ttttattaat
     7981 ataatgaaat acatggttaa tttctatatt gtcaagaaac tatgatatat gttataagtc
     8041 tatactattt aaaataaact tataacatat attttttata atatagtgca tgaaaaattt
     8101 atttaactaa ttttagatat ttattgacaa ctgattcagc caagcatttt gatgaatcaa
     8161 caatatttat tgaaggatat gatttttcta aaactacatt taaatcagta caagcaatta
     8221 ctatattttc tatagattca tttttaacat cttcgataag tttattccaa atatcaatat
     8281 tgtgtggatt ttctttatcc atttttatat tttgaataag attgtttaat tttatttgcc
     8341 attcatcttt aaatataaat tcatgtccat tatgtattat accattctgg taaattgtag
     8401 actcaaaagt tgaactagtc gaaaaaagag ttactttttg tgagatagta ggtaattttt
     8461 taactgtttc ttctacaata tttaatattg gtatattaat agactctttt aattctttaa
     8521 agtatatatg tgctgaattg catggcattg caataaaatt tacaccagtt gattcaagct
     8581 tttgtaatcc atcaattata gtttctttca taagttcatg atttattgga cggtcaatat
     8641 aaaatggggt aggtaatgaa tatatcatca tctttggaaa ttcatcatca tattttgctc
     8701 catattgaga ttgacactca tcaataatta aatcaacaaa aggggctgtt gaccttggac
     8761 ccattccagc caaaatacca attaattttt cattcataaa aattatctcc tttatatata
     8821 aatatattta tgtataaaat aaaaatctat aaaagcataa aattatattt tataatagat
     8881 tatattgtac acttgtataa tataaatata aagtgatttt ttagattata tattttaata
     8941 tactttctta tataaaaatt attttaaatc aagattatct agtattttta aaaatatttt
     9001 tacagcagta tccaagtcat ctacagaaac actttcatta ggattatgac ttacgccccc
     9061 agcacatctt ataaatacca taccaatatc agttatatta tccatttcct gagcatcatg
     9121 gccagcacca ctataaatat aaaaaggatt aagatttaaa tctataaaac ttttttctat
     9181 gatttttgtt attttattag aacatggtac aggaacattt tcaaaagcaa gttcacttgt
     9241 ataattaagt tttctatttt cacatatatg tgatatttca ttaaatatct tttctacaga
     9301 attatcaaga atttcttgtg aacaagagcg tacatcgagt gtaaattcag ctctttcagg
     9361 taccacattt gatgaagatg gatagaaatt catctttcct acagtagcaa ccaaatcagc
     9421 agtcgtttta gctacttttt cgatagctaa tacacattca caggcacaac atccagcatc
     9481 aagtctcata ttcattggaa gtgtaccagc atgtccagac ttaccattta ctgatatctt
     9541 aaaactttta aatcctgtaa tacttgatac aattccagca ggaagagatt cattttctaa
     9601 aacaggaccc tgctcgatat gaaattctaa atatgcatct acatcttttc taggatgcaa
     9661 atttgttaag ttttttgtat taaatccaaa ctttgttaca gcttcttcaa gtgtaattcc
     9721 attttcatca acagatttaa gaagttcctc tttaaaagta ccagcaaaaa ctttacttcc
     9781 cattaaagaa gtttcaaatc tagttccttc ctcttcagcg aaagcaatta gcttaatatt
     9841 gaaaggataa gacctattat tgtgttttgc ttcttcaaga ccaactagag gcactattat
     9901 acctaacata ccatcaaata tacctccaca ctttacacta tcttgatgag atgcaactac
     9961 taatgtggga gcatttggaa agcttgattt atatgtacct ataacgtttc caatgtcatc
    10021 aatttcaata tcaagattta aaccttccat ccatgaacta attaaatcaa tagatttttt
    10081 atgttcttga gtcaagataa gtcttgtaag accatttgtt gttgaactta tttttcctaa
    10141 tgtttgtaga taatccatac atttttttcc taacatattt acctcctaaa aatataattt
    10201 ttatttaagc taagattagc ttttatactt ataatttttg aactttcaaa taattttgta
    10261 tgtatagtaa aatactattt tagtattaat aatgatataa aaacataaag tctgtagacg
    10321 aagagcagaa gttttaagtt aaaaatataa aatatgattt ttattattat agtatttttc
    10381 tataataata tctctttcca gttagaggat aattttcaag tgaaaatact ttatggtatc
    10441 caaatttctc ataaaattta ggtgcttgaa aactgaatgt atctaaaaaa acatatttac
    10501 aacctcgttc tttagcaatt ttttcagtct tatataaaag ttgacttcca gtacctttat
    10561 atctaagctt ctcactaacc cataagtatt ttatagaaag ccaattacca tgagtaacac
    10621 ctataaaacc tgcaacaatt ttacctgctt tatctcgaat atatattcct aaatccactg
    10681 ggtttttatc ttcaagtcta gcaagattat attttaataa tccttgaaaa atagtatctt
    10741 catcttgttt ttctattttt tctgtaattt ctaattccat atttgaactt tctccttgta
    10801 taatcttttg tatattggta ttttttaata aaatcagtag aaagaatata gtttaacatt
    10861 attctaatag gcatttatgc taatgtcaaa ctaataatac ttattcttaa ttttatattg
    10921 ttgatattaa attttttaaa ataaaaatgt agtttaagtt atataaaaag aaatcatcaa
    10981 taaatttagt aaacctaaat tgttgaatat taaaataagt taatttaata cataaaaact
//
LOCUS       DAMJWO010000106        10405 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.109, whole genome shotgun sequence.
ACCESSION   DAMJWO010000106 DAMJWO010000000
VERSION     DAMJWO010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10405
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.109"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..589)
                     /locus_tag="PC366_003268"
     CDS             complement(<1..589)
                     /locus_tag="PC366_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2578755.1"
                     /translation="MFNKNEILKKLIEEYDVKTTTDIQDMLKDLFASTIHQMLEAELD
                     DHLGYDRYDNKNKNTKNSRNRYRNKNVKSDFGEITLNIPRDRNGDFEPKVIRNYENDI
                     SGIENQVIGMYSKGMSTRDISSHLKSIYGIDISHSLIAKITDRVLPLAHEWQSRALDM
                     VYPIVFMGAIHYKVRSEGRIINKAAYIAIGVNLEGI"
     gene            complement(776..1933)
                     /locus_tag="PC366_003269"
     CDS             complement(776..1933)
                     /locus_tag="PC366_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HDF2578756.1"
                     /translation="MYLVISKKKAIFLGVILVIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGAAKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKTVELTILREDKQLNFKVKTDQIIEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTAAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
     gene            2087..2656
                     /locus_tag="PC366_003270"
     CDS             2087..2656
                     /locus_tag="PC366_003270"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HDF2578757.1"
                     /translation="MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIR
                     EPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFDSIPKETHDAQLDYIVTETRIITPNN"
     gene            complement(2838..3254)
                     /locus_tag="PC366_003271"
     CDS             complement(2838..3254)
                     /locus_tag="PC366_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578758.1"
                     /translation="MNVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(3480..4574)
                     /locus_tag="PC366_003272"
     CDS             complement(3480..4574)
                     /locus_tag="PC366_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578759.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDKLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPVIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDKHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            complement(4997..5938)
                     /locus_tag="PC366_003273"
     CDS             complement(4997..5938)
                     /locus_tag="PC366_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HDF2578760.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKSF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVPVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGINAR
                     VINMSSIKPIDKDLILESAKETNAIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIIKTVKEAIIAKRM"
     gene            complement(5931..6758)
                     /locus_tag="PC366_003274"
     CDS             complement(5931..6758)
                     /locus_tag="PC366_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDF2578761.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            complement(6929..7312)
                     /locus_tag="PC366_003275"
     CDS             complement(6929..7312)
                     /locus_tag="PC366_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDF2578762.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            complement(7281..7568)
                     /locus_tag="PC366_003276"
     CDS             complement(7281..7568)
                     /locus_tag="PC366_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HDF2578763.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            complement(7601..8758)
                     /gene="alr"
                     /locus_tag="PC366_003277"
     CDS             complement(7601..8758)
                     /gene="alr"
                     /locus_tag="PC366_003277"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDF2578764.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEESVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            complement(8773..9363)
                     /locus_tag="PC366_003278"
     CDS             complement(8773..9363)
                     /locus_tag="PC366_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578765.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQGDKILVKNP
                     KISDVVELPNTGKNNQYLFVGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            complement(9384..9845)
                     /locus_tag="PC366_003279"
     CDS             complement(9384..9845)
                     /locus_tag="PC366_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDF2578766.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            complement(9860..10240)
                     /locus_tag="PC366_003280"
     CDS             complement(9860..10240)
                     /locus_tag="PC366_003280"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HDF2578767.1"
                     /translation="MNIFDIGVDIIEIDRIRKAVDKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRLFNFKDIEVLRNEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
BASE COUNT         3302 a         1946 c         1100 g         4057 t
ORIGIN      
        1 ttataccttc taagttaaca cctatggcta tatatgcagc tttgtttatt attctacctt
       61 cacttctaac tttataatgt atagcaccca taaatacaat tggataaacc atatcaagag
      121 ctctgctttg ccattcatga gctaaaggta gaactctatc agtaatttta gctattagag
      181 aatgagatat atcaattccg taaatactct taaggtggct tgatatatct cgagtagaca
      241 taccttttga gtacattcca atcacttggt tctctattcc tgatatatca ttttcataat
      301 ttctaattac ctttggttca aaatctccat ttcgatctct tggaatattt aaagttattt
      361 ctccaaaatc tgatttaaca tttttatttc tatatctatt tctagagttt ttagtatttt
      421 tattcttatt gtcatatcta tcataaccta aatggtcgtc aagctccgct tctaacattt
      481 gatgaattgt acttgcaaat aaatctttta gcatatcttg aatatctgta gttgttttaa
      541 catcatattc ttcaataagt ttttttaata tttcgttttt gttaaacata aaaagtgtgc
      601 accttcctta tatatagtga tatttaatat tttaattatc actacttttt agaagaatac
      661 acactttatt ttaaagaccc acaaaagagt gcctcataaa ctaaaaagtt aattttgaga
      721 cactcctttt attaaggttc tttattttac aatataagtt tataaaaatt aaactttatt
      781 tatcaatctg ttctctaagc catttagtcg ctacatctaa ctgtttattt tcatcttttt
      841 cttcaatagt aggctttatg cctttttcat tgatataatc tccattaggt gtaaaatatt
      901 gagcagtagt taacttgtat cctgttccat ccttcaatct tacaactgat tgtaccaacc
      961 ctttaccaaa agttgtagtc cctacagaaa taccttcttt attatcaacg attgcagctg
     1021 ttaatatttc agcagcagaa gcactttctc cattagttaa cactactatt ggaagtccca
     1081 atttttcttt atcagatttc aagtactcag tatttccctt attatctttt gtatatacta
     1141 tagttccttc accaattaac tcatcagcaa cttctttaca tatatctagc attccaccag
     1201 gattatttct aaggtctatt actaatccct tgatattttt tgcttttaat tcttttaaag
     1261 ctttatcaaa gtcagtatat gtacttgata taaattgggt aatttctata tatcctaaat
     1321 cattatcaat tactttactt tctatactct tctcaattat ctggtctgtt tttactttaa
     1381 agttcaattg tttatcttct cttaatatag tcagttcaac tgttttccct tttttaccct
     1441 tcatcatacg aacagcttca tctgaatttt tatatgagac agattttcca ttgactttta
     1501 ctaatttatc ccctgatttt acacctgctt tctctgctgg agaatctttc atgggaacta
     1561 ctactaagcc accatctttt gatgccccta tatacatacc tacaccaaca taagaacctt
     1621 cactatcatt aattagattc tccatttcat ctttagtata ataaccagaa tacttatcat
     1681 ttgttcctag aaatagacct tttgctgctc catttaccaa atcagtatct gatacttttt
     1741 tataaaaatc ttgttttata atagattcta gtcctaacaa cttatcatat tttttatagt
     1801 cttcatagag ttctttcgat attacaactt tattccccaa tgtcaactga aatgctgatg
     1861 taaccatagc tgttataatt actaaaatca cccctaaaaa aatagctttc ttctttgaaa
     1921 tcacaagata catctccttt tacataaact attattatta tatgactagc tgttattttt
     1981 attacattta cccaaatata ttgctttatt acaataaatt atactaaaat ttatattaaa
     2041 tacaattgct gtacacatta taacatatta agggaggaat tattttatga aaaaagaatt
     2101 tagaaaaaaa gttattgaat caagaaaaaa taagagtgca aactttgtac ttagtaattc
     2161 aaatttaata actgaaaaat tacttcaaat ggaagatata agaaatgcaa ctaatataat
     2221 gctttatcta aattttaaca atgaagttca aacagataat ttaatcaaaa aacttttgtc
     2281 tctaaagaaa atagtatcaa gtcccatcac aataaaagaa aatcatacat taatccctac
     2341 tcaaataaca gatttaaaag agggattgag aattggagca tatggaataa gagaacctaa
     2401 cgaaaaatca cctacaattg atattaaggc cttagatgtt gtaattgtac cagctgtagc
     2461 atatgatata cattgctata gattaggata tggtggagga ttttatgata gatttttaga
     2521 aaacttaaga aaagatgcta taactattgg catagcattt gacttccaga tattcgattc
     2581 tattccaaaa gaaactcatg atgcacaatt agactacata gttactgaaa ctagaattat
     2641 cactccaaat aattagaaca ttaagtattt ccagacccca tttaatatag taataaatac
     2701 tactgttaat atcttacttt ataagcattt taagtcatgg cttttacaac aataagaacc
     2761 atatacaatt tacttacatt aataaaaacc atgactttat tgtacaatat gcagttattt
     2821 aattataaaa taccttctta tttcgtcgca tttaattcta ttctatctgg aagttcactc
     2881 atatttgttt caacaactat gtatggaaaa gaatcttcct tatctttata ctttatcttg
     2941 actctcaaaa catcctttcc ttcctcaacc acactttcta ttttgtccat ttctatacca
     3001 tatttattat ttcctctagt cactataatg tatattttgt tatcgatttt agccgctaat
     3061 gctctttctt catttgtata cttatccatc acatctaata tcttttctgg tattgaattt
     3121 ctttgtaata ctgtataatc tatgggttta gatttctcta caaacatact tggtatgaat
     3181 ataaatcccc ctataacgaa tacaagagct ataactccat aaattatacc tttaatatta
     3241 aattttacat tcaatcttat cactcctccc atatattcta aatatatgat ttataagctt
     3301 atcttagact ctaaattatt gattagtata tatttatcca taattataaa tatatgtaat
     3361 gtaactaaaa aacatgtttt tcctatttca taataaacga gctaaaaaat aaaaagagct
     3421 atatgaaaac attttcattg ttttcatata gctcttgagt ttacaatatt aaaaaatact
     3481 tatttgtcac tgattccttc ttgatatcca gatgtttttg taatctgtct ataaagaaca
     3541 caaaccagta ttatgacgcc catatatcca gtatatggat ataaaatacc aaccagctta
     3601 tcaaatggta ggaagccacc tataagacct aatatagctg ctattaaagt tattaattta
     3661 aacttaggat gtttatcatc tacaaatcta ttagttactg accataataa aggtacagct
     3721 gttgtatata tacctaatat aagaattatt gagaataaaa ctccaattac tggtgaaatc
     3781 ttatctgcta agaataatga tggtattgct tttgaatata agtttcctat atcagaaaga
     3841 atagctaagt gcatcattat agctgcagcc ataagtgcta ctccacctaa tataccacca
     3901 caaatagctt cttttttgtt agcagcactt gctcctaatc cagttaagaa tgccataaca
     3961 acaattgtgt tataagtagt atatattaca ccagatagat aggcatttgg aactggttta
     4021 gctatcttta cagtgctaag aacttgtgca gcttctccta tattacctat gtttttagct
     4081 aaacttatac caccaactaa aagtgtaaag attattatta taggccctat tccacctagt
     4141 atctttgata atttatcaag acctagtgaa acagttaata atgctactac tgccatacct
     4201 actctaccta caaatggatt taatccatag tattcagtta aagttgctcc tgctcctgaa
     4261 atcattacta cgaaaacacc aaataagaat aaaggtccaa accattcaaa gaatatccct
     4321 aaatacttac cacaataaac acgataaatt ttgataggtt ctttaagttg aagctcttta
     4381 ccttttgaca taactgaagc acccatccat gagaataata ccattgaaat tatcccacca
     4441 ataatacctg caaaaccata aaaagagaag aattgcatta tttcctgtcc tgttgcaaat
     4501 ccagaaccga ttactgttgc tacatacgca cctgcgaaac tgatgactgt tttaacattt
     4561 actttttctg acatatctca gttacctccc catgtgaaat tttttcttct gattaaataa
     4621 ttcgataaac tacctacaat ttcctttaac ataaaataca tgataactgt tttatagctt
     4681 tttagtataa taacttaaaa cttataatct gattttatac cctactcctc ctctcataat
     4741 ttttttagat tcttttatct aagtagtcat tatatataaa attagtttct ctatagatta
     4801 tatattagtc atatttttct gaatagtcaa tatatatttg aatattttct ctatttttgt
     4861 aaaaatttga atattttatt acatttttga tatattgata tcatataaaa aaaagagaga
     4921 tataaattaa tataacactt tatacctctc ttttaaatat attatattat taacaaacat
     4981 gaataattta tatctcttac attctttttg caataatagc ttctttaaca gtctttatta
     5041 tgtcatcaca agttaattca tattttttta acaattcatt tggagtacca gattctccaa
     5101 atgtatcttt aattccaact ttctttacaa tggttggaca agactctcct actacctcac
     5161 ttacagcaga acctaatccc ccaattatgc tatgttcttc tacagttaca atagcattcg
     5221 tttcttttgc tgattctaat attaaatctt tgtctatagg ttttatcgag gacatgttta
     5281 taactctagc atttatacct tcttcttgca acttttcttg tgctaataga gcttcattta
     5341 ccataattcc acaagctata attgatacat cctttccttc tcttaagact gtaccttttc
     5401 ctatttcaaa tttataatct tcatcaaata aaactggtac tgaacttctc cctaatctaa
     5461 cataaacagg tccattatac ttagctattt caaaaataat tttttctgtt tcaactccat
     5521 cagctggaac aagaactgtc atatttggta tagctctcat tatagcaata tcttccacac
     5581 tttcatgaga tgctccatcc tctccaacag taagacctgc atgagtagca catattttta
     5641 catttagctt tggataacaa actgaatttc ttataatctc aaaagccctt cccgtagcaa
     5701 acatagcaaa agtacttgca aaaggtattt taccagcagt tgataatcca caagcagcgc
     5761 ctattaaatt ttgttcagct atacccatat taaaaaatct atctggaaat gacttgtaaa
     5821 aatcatgtgt ttttgtagac tttgataaat ctgcatctaa tactacaaca ttgtcattta
     5881 tttgacctaa ttttactaat gctttaccat atgcttctct cgtcgccatt ttactcattg
     5941 tcagcacctc ctaattcaag caaggctttt tctagctcct catcacttgg agctgtccca
     6001 tgccatcctg cttgattttc cataaaagat attcctttgc cttttatagt ttttgcaact
     6061 atcattgtag gttttttaac tgttgattta gctatatcaa gagccgcaaa tatttggtca
     6121 aaatcatgtc catctatctc aattacattc caaccaaaag ctttaaattt atcaactatt
     6181 gaacctaaac tcattacgct ttctatatct ccatctattt gaagtccatt attatctaaa
     6241 aaagcaatta aattatcaag tttataatgt gcagcactca tagcagcttc ccaaacaatt
     6301 ccttcttgaa cctcaccatc accaagcaaa gtatacacat tccacggagc attatccaac
     6361 tttgatgcca tagccatacc acatgctact gaaaaacctt gacctaaaga accagtagat
     6421 atttccacac ctggcgtgcc tttcatgtct ggatgacctt gtaacatcct tcctatcttc
     6481 cttaatccat tcagttcttc cttatcaaaa tagccttttt cagccaatgt agcatataat
     6541 gctggtgcag catgtccttt tgataataca aatctatctc tatcctccat tttaggattt
     6601 gaagaatcca cattcatttc atcaaagtat aacgcagtaa gtatttcaac tactgataat
     6661 gaccctcctg gatgtccaga tttggctcta tgtatcattg aaactatatc tcttcttatg
     6721 atacgcgcaa tctcatttaa tcctttatgg tctctcatgc aattacctcc cttgagttcg
     6781 taattttata tcaattccat attattatat cacttttatg ctattttttt gcgttatttt
     6841 taattttatt aacatagtac attaaaatta aaccttaaga gatatttaaa agaaaaaagg
     6901 gattgtctaa taaaagacaa atccctcttt aaaaagtaaa caatcctaaa cttatttgaa
     6961 gtccatcatc tacttttatc atcatatttt catctagaca accaattttt tccctcagtc
     7021 tctttttatc gatagttcta atttgctcta aaagaattac tgagtcttta ttaagcccat
     7081 attcattgga acttatctct acatgagtag gtaatttggc tttattaatc tgagatgtta
     7141 tagctgatac tataactgta ggactatatt tattacctac atcattttgt attatcagaa
     7201 caggtctaac gcctccctgc tctgaaccaa caactggact taaatcagcg taatataaat
     7261 caccacgctt tatttcacaa ttagtactca ccttgggcaa tcttcccttc atttttatca
     7321 tcagaagata cttcttcaac tgtcatacct aattcagcta gtgacagatt aatttgaccc
     7381 atttctctat aacccgtttt catagattct ttaatatgaa ttttcttttt ctgagttata
     7441 tagaactgaa aagcagcttt tgcaaaatct tctctgttac tgttctccat ctgaactata
     7501 ctatcaactt cagaaatcag agagtcaggt aaagtaactt ctattttttc tttactctta
     7561 tcgtacacaa aatcgcctcc cagattataa tatcatggtt ttattttagc aaataactgt
     7621 ttatttgtac aagctcatta ttttccatat aaacacggtc aactcttctt gatatcatac
     7681 ataacacttc atagtttata gttcctaagt ctttagctat acgctcagct gtaacttcgc
     7741 cttctccaaa tagtataacc tcatctccaa cttttatgtc tatatctttg tcaattctaa
     7801 ccattatttg atccatacat attctaccaa ctacatcaaa cacttctccc ttaataagaa
     7861 cctttggatt tttttggatt ctagtaaatc catctgcgta tcctattgga actgtagcta
     7921 ttgtttcttt acctgtagtt gtgtatttta gtccataact tattcctaca cctggttcaa
     7981 cttgttttat atgtccgatt tttgatttta atttcatggc tggtcttaat tctaatctat
     8041 ctttaaatac atcatcagat ggataatgac catataatat tattcctgct cttaccatat
     8101 ttaatcttaa atcagggcaa tccataatag ctgcactgtt tgatacatgt tttatagcta
     8161 tttttacacc agcctcatct aatttatcag acataaattt ataattatta gcttgtttat
     8221 aagtgtactc tttacttact tcatcagctg tagcaaaatg agtaaacata ccttctaaat
     8281 cgatatattc taatttattt aattctatta tttcctgtac tgactcctca ttaggttgga
     8341 aacctattct agtcatccct gagtctattt taacatgaac acaggctttt tctcctaaag
     8401 attttgcaat ttcatttatc ttttgtgctg tttctaaaga ataaactgtc atagttattt
     8461 tattttttat agaatcttca aaagcttcgt ctggagtata tcccaagttc aaaataggaa
     8521 gtgttatgcc attttgtcta agttcaattc cttcagcagt tcttgctact gctaagtaat
     8581 ctactttttc tttttctagc aattttgcaa cttctactgc accatgtcca tatgcatcag
     8641 cttttattac tccacaaatc ttaatatctt cttctaataa atttttaata ttatttaagt
     8701 taaatcttaa gttatctaga tttatctctg cccatgtagg cactgttatt ttttgcatgt
     8761 ctttagtccc ccttagtttc tgtattcaaa atctttgtat tttactgtaa atcttggcac
     8821 tccctcttta tctaacactt ccattttttc aggatttttt gtgtcagcat ttacatataa
     8881 tacttgcttg ttaaaatatt tattatcccc aggaataaaa gtctctaaaa ccaaatgtcc
     8941 tttggataac tttactttca tctcctcatt ttgaagatag ttttttataa agtctcctac
     9001 aaaaagatat tgattatttt ttcctgtatt aggtaactcc actacatcac taatctttgg
     9061 atttttaact aatattttat caccttgata ttctatactt ttccctttta aatgttttgg
     9121 ggaaattact tctaatttat agttatcggt ttttttataa gtatgaatta aaacataatt
     9181 gtgtgggctt ttatttccaa ctacttctac ttcagcttta caactgtaat aattcatatc
     9241 agaaatctgc ttttgaaaat ctttgtatac ttcttctttt gtggactgtc gtttttggca
     9301 tcctattaca attataacca gtgccaagaa cataatacat actatggtcc acttttttct
     9361 cacatcacac ctcctacttc agtttattca ttgtataaag cttttattat atcatatcta
     9421 caaattatac ctttaagttt gttgtcatca tctactacag gaactctgtt tattgatttt
     9481 ttaatcatta cattagctac atcatcaaac ttatcatctt catgaacctt tattatatct
     9541 ttagacataa gttctccaac cttataagca gctacttgtt ttatatcttt ttcaactttt
     9601 tttaagtcat ctaagaaaat caatccttgt aatagattta tatagagagg tgcttctata
     9661 tatttttctt ttttaagaat atctgtttca gaaattattc caacaactct attctctgaa
     9721 tctacaactg gcagacctcc tattttttct gcaattagca tattagctac atctgctata
     9781 ctatcatctt gttttgctac tattacatct gttgtcatta tttcttttgc tgttttatcc
     9841 atcataatgt aatcactcct tagtccttaa ttatggttat cgcatttgct atagcataat
     9901 cttttgaatg tgatattgaa acttttattt ctaaaacatt ataatctatg cacatttttg
     9961 ctagattatt ataagttttt actattggtt ttcccatttc atttctgaga acttctatat
    10021 ctttaaaatt aaacaatcta attcctgtac ctatagattt acttatagct tccttggctg
    10081 cgaaattacc tgctatactt tctgctttaa aattcttaga attaaaatac tctatttctc
    10141 tatctgtaaa tatcttctcc aaaaacctat tatttttgtc tacagccttt cttattctat
    10201 caatttcaat tatatctacg ccaatatcaa atatattcat tgttcctcca gaaaatttat
    10261 aatacttctt tcaataatta ataatgaatt tataaattta ctatcgataa tacacattat
    10321 tatttagttt atgttactta tcttaattta ataatcatta taataaaact gtaactttta
    10381 aaattatttg taatgaatat tatat
//
LOCUS       DAMJWO010000107         9695 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.111, whole genome shotgun sequence.
ACCESSION   DAMJWO010000107 DAMJWO010000000
VERSION     DAMJWO010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9695
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.111"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            203..1606
                     /locus_tag="PC366_003281"
     CDS             203..1606
                     /locus_tag="PC366_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDF2578768.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFMLKKHDIASTYTIASMTPKLNMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     TSLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
     misc_binding    1697..1937
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1980..2678
                     /locus_tag="PC366_003282"
     CDS             1980..2678
                     /locus_tag="PC366_003282"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HDF2578769.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILKGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     gene            2701..3702
                     /gene="trpS"
                     /locus_tag="PC366_003283"
     CDS             2701..3702
                     /gene="trpS"
                     /locus_tag="PC366_003283"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HDF2578770.1"
                     /translation="MSEKKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANAIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
     gene            complement(4354..6984)
                     /gene="cdtB"
                     /locus_tag="PC366_003284"
     CDS             complement(4354..6984)
                     /gene="cdtB"
                     /locus_tag="PC366_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094607992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylating binary toxin binding subunit
                     CdtB"
                     /protein_id="HDF2578771.1"
                     /translation="MKIQMRNKKVLSFLTLTAIVSQALVYPVYAQTSTSNHSNKKKEI
                     VNEDILPNNGLMGYYFTDEHFKDLKLMAPIKDGNLKFEEKKVDKLLDKDKSDVKSIRW
                     TGRIIPSKDGEYTLSTDRDDVLMQVNTESTISNTLKVNMKKGKEYKVRIELQDKNLGS
                     IDNLSSPNLYWELDGMKKIIPEENLFLRDYSNIEKDDPFIPNNNFFDPKLMSDWEDED
                     LDTDNDNIPDSYERNGYTIKDLIAVKWEDSFAEQGYKKYVSNYLESNTAGDPYTDYEK
                     ASGSFDKAIKTEARDPLVAAYPIVGVGMEKLIISTNEHASTDQGKTVSRATTNSKTES
                     NTAGVSVNVGYQNGFTANVTTNYSHTTDNSTAVQDSNGESWNTGLSINKGESAYINAN
                     VRYYNTGTAPMYKVTPTTNLVLDGDTLSTIKAQENQIGNNLSPGDTYPKKGLSPLALN
                     TMDQFSSRLIPINYDQLKKLDAGKQIKLETTQVSGNFGTKNSSGQIVTEGNSWSDYIS
                     QIDSISASIILDTENESYERRVTAKNLQDPEDKTPELTIGEAIEKAFGATKKDGLLYF
                     NDIPIDESCVELIFDDNTANKIKDSLKTLSDKKIYNVKLERGMNILIKTPTYFTNFDD
                     YNNYPSTWSNVNTTNQDGLQGSANKLNGETKIKIPMSELKPYKRYVFSGYSKDPLTSN
                     SIIVKIKAKEEKTDYLVPEQGYTKFSYEFETTEKDSSNIEITLIGSGTTYLDNLSITE
                     LNSTPEILDEPEVKIPTDQEIMDAHKIYFADLNFNPSTGNTYINGMYFAPTQTNKEAL
                     DYIQKYRVEATLQYSGFKDIGTKDKEMRNYLGDPNQPKTNYVNLRSYFTGGENIMTYK
                     KLRIYAITPDDRELLVLSVD"
     gene            complement(7037..8428)
                     /gene="cdtA"
                     /locus_tag="PC366_003285"
     CDS             complement(7037..8428)
                     /gene="cdtA"
                     /locus_tag="PC366_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylating binary toxin enzymatic subunit
                     CdtA"
                     /protein_id="HDF2578772.1"
                     /translation="MKKFRKHKRISNCISILLILYLTLGGLLPNNIYAQDLQSYSEKV
                     CNTTYKAPIERPEDFLKDKEKAKEWERKEAERIEQKLERSEKEALESYKKDSVEISKY
                     SQTRNYFYDYQIEANSREKEYKELRNAISKNKIDKPMYVYYFESPEKFAFNKVIRTEN
                     QNEISLEKFNEFKETIQNKLFKQDGFKDISLYEPGKGDEKPTPLLMHLKLPRNTGMLP
                     YTNTNNVSTLIEQGYSIKIDKIVRIVIDGKHYIKAEASVVSSLDFKDDVSKGDSWGKA
                     NYNDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPVNNPNPELDSKITNIENALKR
                     EPIPTNLTVYRRSGPQEFGLTLTSPEYDFNKLENIDAFKSKWEGQALSYPNFISTSIG
                     SVNMSAFAKRKIVLRITIPKGSPGAYLSAIPGYAGEYEVLLNHGSKFKINKIDSYKDG
                     TITKLIVDATLIP"
     gene            complement(8818..9564)
                     /gene="cdtR"
                     /locus_tag="PC366_003286"
     CDS             complement(8818..9564)
                     /gene="cdtR"
                     /locus_tag="PC366_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family response regulator CdtR"
                     /protein_id="HDF2578773.1"
                     /translation="MDILIFDNDVCFGIKLKEKINNILIKEGFDNDVIRLYYNANLLL
                     KELTEKNKVKIYFIVVDAKYKISNELCDGLWIAQKIRESDYISPIIFLTNHIEMILGI
                     FDYRLEVMDFILKHDMEIAESKIKACIKIAHKRYVKEKNYRSNFFTIYSDSSLWKISF
                     DEVIYFETSAIPHKIKLVTTSRIFEFYKSLRSLSDLDACFIRVHKSFVVNKYHIVSLD
                     LKKNNIKMSNGHICRISNTYRNILKNIIKT"
BASE COUNT         3337 a         1273 c         1398 g         3687 t
ORIGIN      
        1 tatcattaga attaaagtgg taaaactttt aaatttatca tttttaataa gatttgattt
       61 caaagtattt aaggtttatt attaaaactg tttttgaata tgcaaatatt ttgaaaaata
      121 tcagtttaat aataatgaat ctattttatt aattttgaaa ttaaatttaa aataattaat
      181 agagagggga aatgaaatta ggatggaaaa gaaaaaaata ggcctatgga gtttggtatt
      241 tatgaatgta tcagctttat atggtataag atggatagct aagtctacag catcaagctt
      301 tggtttagga ttaggtgcaa tacctatgtg gttattattc tcatttatat actttgtacc
      361 aggagcttta atttgcgctg aattagcttc tacatatcaa aagggtgatg gaggtcttta
      421 cgattgggtt aaggaagcct ttggagaaaa gtatggattt ttagtttctt ggttaaactg
      481 gacagctaaa atattttggt attcttcatt tttaactttc ttagcagtaa atgtttctta
      541 tacaatagga aatccagctc ttgctgataa taagatgttt gtacttatat tatctttaat
      601 aatattctgg gcattatctc ttatagcaac taaaggaata agttttacaa aaatatttac
      661 taatacaggt gcattaggtt caacaatacc aagtgctata cttataatat tttcatttgt
      721 agcagtattt atgttgaaaa aacatgatat agcttctaca tatacaatag cttcaatgac
      781 tccaaaactt aatatggatg catttgttgc tatatcagct ataatgtttg gtttagcagg
      841 agcagagact gctgctaact tcataacaga aatagataag cctgaaaaga acttccctaa
      901 ggcaatatta atatcagctg gaatagtagc ttcattatat gtattaggtt caattgcaat
      961 aacaatgata ataccaccag accaaattac tgcttctaaa ggtgtattag atgcactttc
     1021 tgctgtttgt acgtctttag gaattggttc ttggttggtt caattaatag cttttggtat
     1081 agctttctca gtattaggag caatagttct ttatatagca tcaccaataa aaatgttatt
     1141 tggtagtgtt aaaaaaggaa tatttccaga tagtttggta gaggtaaatg aacacaagat
     1201 accttctaaa gcagttatac ttcaagcaat aatagttact ataatactat tggtgactac
     1261 attaatgcct tctgttgatg ctatatacaa tgttcttgta actatgacag cattaactgc
     1321 attattccca tatgtattat tatatgcttc ttatattaaa ctaagaaaag agagaccaga
     1381 tgaaattaga ccttatacta tggcaaaatc aacaagtact tgcctaggtt tagcaaaaat
     1441 ggttttagtt gtaactgtag ttggtatatt attatctgca gcaccagtta tgccgacatt
     1501 tgctgaaaat gttatatatg agatagagat gattggtgga ggtcttctag ttatattatc
     1561 tggtctatgg ttatggaata gatatgaaaa gaaaacagct aaataaaatg tattttaaaa
     1621 atttcttttg gatattataa tatatagttg acaatttata gtgtaaggaa tattataaaa
     1681 taaagaaatt aataaattaa atcctgagat aagaaatagt aaataaatat atttttgcac
     1741 agagaattaa ggatgctgag aacttaataa aaagtattta ttgaatgggt ctttgaggag
     1801 taaaatgaaa tgtaatttaa gattacagag tatttgatat cgtgtatgca cgttatagca
     1861 tatattaaga tatatatatt cagttttgag tgtatataaa tttaggtggt accacggaaa
     1921 atatatccgt cctattgatt taggacggat tttttaatat agaaaattta ggaggaaaaa
     1981 tgaacgtaat aggaattata ggtgcaatgg atgaagaagt tagtatttta gttgatttaa
     2041 tggatattag agagactata aaaaaagcta gcttagaatt ttataaggga attttgaaag
     2101 gtaagaatgt agtgttagta aagtgtggta taggtaaggt taactctgct ctttgtgccc
     2161 agatactaat aagcgaattt aaggttgatg ctattgttaa tacaggtgtt gcaggagctt
     2221 taaatgaaaa acttgatgtt aatgatatag taatatcaac tgatgctata cagtatgatg
     2281 tagatactac agcatttgga gaccctaagg gagttatacc aagaatgaag acttctgtat
     2341 ttaaagcaga tgaaagactt atagatgctg cttacaaatc ttctgtggaa gaagtaaaga
     2401 ctcataaagt attaaaagga agagtagtta caggagataa atttataaat tctaaagaat
     2461 taaaagaaga attagtaaat gattttggtg gatattgtgg agaaatggaa ggtggagcta
     2521 tagctcatgt atgctattta aataatactc cattcgtaat aataagagca atgtctgata
     2581 aggcagatgg aagtgctgat gttacttatg atgtatttgt acatgatgct gccaataact
     2641 ctaaagacat agttttaaat atgttaaaat caatataaat atataaggag gtacaaaaaa
     2701 atgagtgaaa aaaaagttat atttagtgga gcacagccat caggcaaaat gactttagga
     2761 aattatttag gagctataaa aaactggact gaacttcaag ataattatga ttgctattat
     2821 agtatagttg atttacatgc aataacagta cctcaggacc ctaaagtttt aagagcgaat
     2881 gctatagaat tacttgctca atatatagct tgtggattag acccagaaaa aaatactata
     2941 tttatacaat cacatgtcaa agagcatgtt gaacttatgt gggtattgaa tactatgact
     3001 tatatgggtg aattaagtag aatgactcaa ttcaaagata aatcacaaaa gagtgaagca
     3061 aatctaaatg caggtttatt cacatatcca gttcttatgg ccgctgacat attgttgtat
     3121 caaactgacc tagttccagt tggagatgac caaaaacaac atttagaatt agctcgtgat
     3181 ttagcaaata ggtttaataa tagattttca cctacttttg tagttccaga aggatactac
     3241 ccaaaaggtg gagcaagagt gatgagtttg caagagccaa ctaaaaaaat gagtaaatcc
     3301 gattcaaatg aaaatgcatt tatactatta gcagatgatt cagattctat aaagagaaag
     3361 ataaaaagaa gtgttactga ttctttaggt gttgtaaaat acaatgatga acaaccaggt
     3421 attaaaaatc taattgatat atattctaat ttaagtaaaa agagtgtaga agagattgta
     3481 aacatgtatg aaggaaaggg ttatggcata tttaaagaag atgtggctga agtagtatca
     3541 gaagctttaa gacctataag agaaaaatat gttgaccttc ttaataataa agattattta
     3601 gaaaaaatat atagtatggg agcagaaaaa gccgaaaaac aagctagaaa aactcttaga
     3661 aaagtttata aaaaagttgg atttatagag agaagatact aattattagc tatctttact
     3721 tgataaataa attttaaagt tattaaaaag gtatatgata tgaaagagag agtctcaaag
     3781 tgaacttttg ttcatgagac actctttttt gtatgaaata aaatatattt taatcacttc
     3841 aacaatgaaa aagaggatta tctctatttt gagacagcat cttttgataa taaaaaaaga
     3901 tgagcttttg ctcatctcaa aggggttaga ttattcttac tttggggaaa gtagaataaa
     3961 ggtaaaagtt aactgatgtc aactttgtct tttttgcata tcactactga gcataaaaaa
     4021 atcagaaaac catagccttc tgaaacaact tctaacatac attgtatttt atacccaata
     4081 tgtaatttat gagttaattt taactcttat aatggaaatt gtcaataata tatcaaaaaa
     4141 atatttttta aatttatata attaaatgaa tttatgttta tatataggtg atatgataca
     4201 gataattatc tttataatac aatatagttc taaaaaagaa tatgttagaa gaagagaata
     4261 tttaaataaa aaatacctta taaagttaat tttttagtac tttataaggt aaatatatat
     4321 tgtattgtgg ggacaaattt aaatcatttg atactaatca acactaagaa ctaataactc
     4381 tctatcgtct ggagtaattg catatattct taatttcttg tatgtcataa tattttctcc
     4441 acctgtaaaa taactcctaa gattaacata attagtttta ggctgatttg gatctcctaa
     4501 ataattacgc atttctttat ctttagttcc aatatcttta aatccagaat attgtaaagt
     4561 agcttcaact ctatattttt ggatataatc gagagcttct ttattagttt gtgttggtgc
     4621 aaaatacata ccatttatat aagtatttcc tgtacttgga ttaaaattta aatctgcaaa
     4681 atatatttta tgtgcatcca ttatttcttg gtcagttgga attttaactt ctggttcatc
     4741 aagtatttca ggagtactat ttagctctgt aatagataag ttatctaagt atgttgtacc
     4801 actaccaatt aatgttatct ctatattaga agaatctttt tcagtagttt caaattcata
     4861 actaaatttt gtatatcctt gttctggtac caaataatcc gttttctctt cttttgcttt
     4921 tatctttaca attattgaat tagatgttaa aggatccttt gaatatccac taaaaacata
     4981 acgtttataa ggttttagct cagacatagg gattttaatc ttcgtctcac catttaattt
     5041 atttgctgag ccttgtaaac catcttgatt cgtagtattg acattactcc atgtactagg
     5101 gtaattatta taatcatcaa aattagtaaa gtaagttggt gtttttataa gtatattcat
     5161 tcctctttca agtttaacat tatatatctt tttatcagac aaagttttta aactatcttt
     5221 aatcttattg gctgtattat catcaaatat gagttcaaca caactttcat ctattggtat
     5281 atcattaaaa tataacaaac catctttttt agtagcgcca aaagcttttt caattgcttc
     5341 tccaattgta agttcaggtg ttttatcttc tggatcctgt aaatttttag cagtaactct
     5401 tctttcgtaa gattcattct ctgtatctaa tataatagat gcagaaatac tgtcaatttg
     5461 acttatatag tctgaccaac tatttccttc tgttactatt tgtccagaac tattttttgt
     5521 accaaaattt ccacttactt gtgttgtttc taatttaatt tgctttccag catctaattt
     5581 ttttaattga tcataattta taggaatcag tctagagcta aattgatcca ttgtgttaag
     5641 agctagaggt gaaagccctt ttttgggata agtatctcca ggagatagat tattgccaat
     5701 ttgattttct tgtgctttga tagttgataa tgtatctcca tctaacacta aatttgttgt
     5761 tggtgtcact ttgtacatag gtgcagtacc tgtgttgtaa tatctaacat ttgcatttat
     5821 atatgcagat tctcctttgt ttatacttaa tccagtattc catgattctc cattactatc
     5881 ttgaacagca gttgaattat ctgttgtatg ggaataattt gtagttacat tagctgtgaa
     5941 tccattttga tatcctacat taacagacac accagctgta ttagattcag ttttactgtt
     6001 agtagtagct ctggaaacag ttttaccttg atcagtagag gcatgttcat ttgtagatat
     6061 aattaatttt tccataccta ctccaacaat tggatatgct gcaactaacg gatctcttgc
     6121 ttcagtcttt atagccttgt caaaagaacc tgaagctttt tcataatctg tatatggatc
     6181 tccagcagta tttgactcta aataatttga tacatatttc ttatagcctt gttctgcaaa
     6241 actatcttcc cacttaactg caattaagtc cttaatagta tatccatttc gttcatatga
     6301 atctggtata ttatcattat ctgtatccaa atcttcgtct tcccaatcag acatcaactt
     6361 tgggtcaaag aaattgttat ttgggataaa tggatcatct ttttctatat tagaataatc
     6421 tcttaagaat aaattttctt ctggtataat tttcttcata ccatctaatt cccaataaag
     6481 attaggtgat gataaattat ctattgaacc taaattttta tcttgtagct ctattctaac
     6541 tttatattct ttaccctttt tcatattaac tttaagtgta tttgatatag tactctcagt
     6601 atttacttgc attaagacat catctctatc agttgataat gtatattcac catccttaga
     6661 aggaattatt cttcctgtcc atcgtataga ttttacatct gatttgtctt tatccagaag
     6721 tttatctact ttcttttctt caaattttaa attaccatct tttatgggtg ccattaattt
     6781 taaatcttta aagtgctcat ctgtgaaata atatcccatt aatccattgt ttgggagtat
     6841 atcttcattt acaatttctt ttttcttatt agaatgatta cttgtactag tttgagcata
     6901 tacaggatat actagtgctt gactaactat agctgtaagt gttaaaaaac ttaatacctt
     6961 tttattcctc atttgtattt tcattgtttc tcctccttaa atttgaaaaa tattaaatta
     7021 tttatgtgaa aaaatattaa ggtatcaatg ttgcatcaac aattaatttt gttatagtac
     7081 catctttgta agaatcaatt ttattgattt taaatttgct tccatgattt aaaagcactt
     7141 catattcacc tgcataacct ggaatagctg atagataagc tccaggagaa cctttaggta
     7201 tagttatacg tagtactatt tttcttttag caaatgcact catattcaca ctaccaatac
     7261 tagtactaat aaagtttgga taagacagtg cttgtccttc ccattttgat ttaaaagcat
     7321 ctatattttc tagtttgtta aaatcatatt caggggaagt aagagttaaa ccaaattctt
     7381 gaggaccaga tcttctatat acagttaaat tagttggaat aggttcacgt tttaatgcat
     7441 tttcaatgtt tgtgatttta gaatctaatt ctgggttagg attatttact ggaccatttg
     7501 atattaaata attattaatt gcagtatatc ctccacgcat ataatcattt acatcagcaa
     7561 gttcattagg tgttaattta ttactccaat cattataatt tgctttaccc caagaatccc
     7621 ccttacttac atcatcttta aaatcaagac tacttacaac agatgcttct gctttaatat
     7681 agtgcttccc atctataact atacgaacaa ttttatctat ttttatacta tatccttgct
     7741 ctattaatgt acttacattg ttagtatttg tatatggtaa cataccagta tttctaggta
     7801 attttaagtg cataagtaat ggtgtaggtt tttcatcacc ttttccaggt tcatataaag
     7861 aaatatcttt aaatccatct tgcttaaata atttgttttg tatagtttct ttaaactcat
     7921 taaatttttc taatgaaatt tcgttttgat tttctgttct tattacttta ttaaatgcaa
     7981 atttttctgg agattcaaaa taatagacat acataggttt atctatttta ttttttgata
     8041 tagcatttcg aagttcttta tattcttttt ctcgagaatt tgcttctatt tgataatcat
     8101 aaaaataatt tcttgtctga gaatatttac ttatttctac agaatctttt ttatatgatt
     8161 ctaatgcttc tttttcagat ctttcaagtt tttgctctat tctttctgct tcttttcttt
     8221 cccattcttt agccttttct ttatctttaa gaaaatcttc tggtctttct ataggagcct
     8281 tgtaagtagt attgcaaact ttttcactat agctttgtaa gtcttgtgca taaatgttat
     8341 taggtaacaa accacctaaa gttagatata atatcaacaa tatagatata caattactaa
     8401 tccttttatg tttcctaaat tttttcattt attctccctc ccaatattag tttaattaac
     8461 tcttgaactt taatttattt agattatata atctaaataa gaatttttta tataaatttc
     8521 ataaaatatg taactatata tcataaaaat atgtatttat atgatatgtc agtacaaaat
     8581 aacaactgaa tattttaaag agactatttc atacttttat gatttaatga gctatcttgt
     8641 tgaatcataa tctaggaaca atggttgcaa tgtctaatag aaattgtata tgatatagtc
     8701 attatgtgtt ttttcacaaa acgattatta tatagaggat tcttaggaac tacttttttt
     8761 gtataaaaaa agagatggtt caaattctta tcttgagaca tctctttttt ctatttatta
     8821 tgttttaata atgttcttta aaatatttct atatgtatta gatatacgac atatatggcc
     8881 attactcatt ttaatattat ttttctttag gtcgagagaa acaatatgat atttattaac
     8941 tacaaaagat ttatgtacac gaataaagca tgcatctaaa tctgataaag accttaaact
     9001 tttatagaat tcaaatattc ttgaagtagt cactaatttt attttatgtg gaatagcgct
     9061 tgtttcaaaa tatataactt catcaaatga aattttccat agtgaggaat ctgagtagat
     9121 agtaaaaaaa ttagagcgat aatttttttc tttaacgtat cttttatgag caattttaat
     9181 acaagctttt attttacttt cagcaatttc catatcatgt tttaatataa agtccataac
     9241 ttctaaccta taatcgaaga tccctaaaat catttctata tgatttgtaa gaaatatgat
     9301 tggactaata taatctgatt ctctaatttt ttgtgctatc cataatccat cacataattc
     9361 attacttatc ttgtattttg catctacaac tataaaatat atttttactt tatttttttc
     9421 agtaagttct tttaataaca aatttgcatt ataatataat cttataacat cgttatcaaa
     9481 accttctttt attaaaatat tatttatttt ttcttttagt tttattccaa aacaaacatc
     9541 attatcaaaa attaatatat ccactaaata ccctcctata aaaaattcaa aagtaaaaaa
     9601 actaaaagta ttttataaaa aatacgtaaa ataacactag gagataaata aaattaagga
     9661 tagttagaat taaggtatat ttatgcttgt ttata
//
LOCUS       DAMJWO010000108         9538 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.112, whole genome shotgun sequence.
ACCESSION   DAMJWO010000108 DAMJWO010000000
VERSION     DAMJWO010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9538
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.112"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(118..771)
                     /locus_tag="PC366_003287"
     CDS             complement(118..771)
                     /locus_tag="PC366_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2578774.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKFMRENDLENVERVLREHWKTIPIAEMKKEKLL"
     gene            complement(1016..2881)
                     /locus_tag="PC366_003288"
     CDS             complement(1016..2881)
                     /locus_tag="PC366_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase C-terminal domain-containing
                     protein"
                     /protein_id="HDF2578775.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVNEGYNIKSISL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDN
                     PKKNSFIYGNWEDIPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDN
                     DSVINKWVNMGIKGWRLDVADELPTKFIRELKKELKKADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYRDVIKIRNKNKLLSSGNTEFIYTNNDSVFSFIRVDENNDRMLILVN
                     RSENVESISLCIESSFIEEIPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN"
     gene            complement(2886..5306)
                     /locus_tag="PC366_003289"
     CDS             complement(2886..5306)
                     /locus_tag="PC366_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HDF2578776.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIE
                     AEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNIDNLFDKVAIHINDTHPTLCIPELMRILL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMMKELLPRIYMIIEEINRRYVE
                     ELNNKGYEQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            complement(5320..6762)
                     /gene="glgA"
                     /locus_tag="PC366_003290"
     CDS             complement(5320..6762)
                     /gene="glgA"
                     /locus_tag="PC366_003290"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011053260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HDF2578777.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTDAVLEAISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNRDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSID
                     KKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            complement(6791..7921)
                     /gene="glgD"
                     /locus_tag="PC366_003291"
     CDS             complement(6791..7921)
                     /gene="glgD"
                     /locus_tag="PC366_003291"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HDF2578778.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGS
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            complement(7923..9083)
                     /locus_tag="PC366_003292"
     CDS             complement(7923..9083)
                     /locus_tag="PC366_003292"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HDF2578779.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKRSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
BASE COUNT         3028 a         1739 c          924 g         3847 t
ORIGIN      
        1 ttattctatc gtagtgcctt agagttttta tttgtattta aagttaaatt tattcttgtt
       61 tttcctttaa tatttaatag taaaataaca aaattataaa aaaaataaag agaaacttta
      121 taaaagcttc tcttttttca tctctgctat aggtatcgtt ttccaatgtt ctctcaaaac
      181 tctttcaaca ttttctaaat cattctccct cataaatttt actacttcaa tatgttgatt
      241 attgctgtat gtcaacattt tatataactc atcttcatta tcactagtat atgactttga
      301 cataaaatta tatcttaaag agttcaatag atttactaac acctgattat ctgatttagt
      361 tatgtatata tcgtgaaatt cattacttaa ttttaaatag ctattgtaat ttttatactt
      421 tatagagacc gccatcattt ctgttaattc ttccattttt actaggtctg attcagttaa
      481 attttgtaat gctgaagaac cggctaacgc atccaatact ccaattacgg aataggtgtc
      541 taatttctcc ttttcctgaa attcttttac tacaaatccc ttattaggta ttttttctag
      601 taaattttca cctgctaacc tagttaatgc ttctctagct ggtgttctac taactccgat
      661 agatttacaa atctcagatt cagtaattct ctgattagct tcatactctc cattttggat
      721 tttctttgat atatagtcat atacttgagt tgtaagtgga tctaccttca taagacgttc
      781 ctccatatta agattataaa agttaaatct ccctacaact ttggtagaga gttcagtttt
      841 atcttactaa tttatataat atcacaatta tgatattttt tatacttctt tgtaatattt
      901 tgaaacacta aaattcttat gataatttat acaaaaaaag tagaaaaagt tttgataaaa
      961 caaaactctt tctacattca ccttattttc tatttatttt tctaaaaaaa gatatttaat
     1021 ttactctaaa aattctaaat gatttagagt ctaaatctac tttcaactca ttattttcaa
     1081 tttgtatagt actatttgca tttttaagac tatactttat aggtatttcc tcaataaaac
     1141 tactctctat acataatgat atactttcca cattttcact tctatttact aaaattaaca
     1201 ttctatcatt attttcatca actctaataa aagaaaatac agaatcatta ttagtatata
     1261 taaattctgt atttccagaa cttaaaagtt tattcttatt tctaattttt ataacatctc
     1321 tataaaaatt aagcatatct tcgtcttcat ttttccatgg ataagttctt ctattatctg
     1381 ggtcaacacc tccacaaaga cctgcttcat ctccataata tatatatggt actccttcaa
     1441 atgtcatctg tatagctaca gcaagcttca ctaaatctac atcatcattt aattccgttt
     1501 tagctcttgt aacatcatgt gttccaatta aatttaaatt agacctaaat gattcttttg
     1561 gataattttc tttaatctgc atatatctat tacaaagttc atatgaatta atttctcctt
     1621 ttaagaaaga aaacatgtta tttctaaaag gataacccat aacagaatct aattcttcac
     1681 ctaataaata acttcttctc tgaccatagc taatcttatt tgatgcatct tcccatactt
     1741 cacctataag aattgagtca tcatctgcct tttttaattc cttttttaac tctcttataa
     1801 acttagttgg taattcgtct gcaacatcta gtctccagcc cttaataccc atatttaccc
     1861 atttatttat aacgctatca ttgtcatata ttatataatc catatagcta tgttctaatt
     1921 catttatatt tggcaatgtc ttaacatccc accaactttt atacttttga ggaaattctt
     1981 caaacatata ccatgaataa tatggagatt ctttagattg atatgcccct aaactattat
     2041 agtttccata catattaaaa tatttactat ctgctccagt atgactaaaa actccatcta
     2101 atactattga tatacctttt tcttttgctt tatcaataag ttctttaaat gtatcttcat
     2161 ccccaaacat tgggtcaatt tttttatagt cacctgtgtc atatttatga ttactagaag
     2221 cttcaaatat agggcttaga tatagtatac ttacacctaa tttttttaaa tatccaagtt
     2281 tattgattat ccctcttaaa tttccaccat ggaaatccca tcttataaca tccccttgac
     2341 tatcctttat gtacataggt atatcttccc aatttccata tatgaaacta ttttttttag
     2401 gattatcaac cttaccacta cgatttccat tattgaatct atctacaaat atatgataaa
     2461 gtattccttc tttgtaccat gttggtactt taaaatcttt gtaaacagtg atttgatatt
     2521 tattaatatc actataatta tattcacaag aatatccatt atctctgttt tttccataaa
     2581 ataaagtctt tatctgacca tccatttcaa catcaacttt aaagtaataa aaataaacac
     2641 ctgtaccatc aaacttttca atcttaccac aaaagcactt tccaagttta tcattatcta
     2701 attcttcatt taaagttatt gttctcattt cttcttctct atttatttct agggaaatag
     2761 acttgatatt gtatccctca tttactttaa cacaaatggt caattcctca tcaaatttta
     2821 aagctccaaa cggagcctta aaatttttat cccaagagtt atattctatt acactttgca
     2881 tttaatcaca cccttttaaa ccaaatgtct tttgcatact cagaaattgt tctatcagaa
     2941 gaaaaaaatc cagagttagc tatattaact aaagacattt tattccattt ttctttatct
     3001 ctatataacc tgtttatatc tgcttgagct tgaccataat tttcaaaatc tctcaataca
     3061 aaatactcat cattgtaagt agtgagtgaa ttataaatac ttcttccttc ttcgccaaga
     3121 ttaggaataa atccatttat taaatcatct accacccttt ttatatccat attagaatga
     3181 tataagtcaa gtgaagaata tccaccatat ttattataat ttagtacttg ttctgcacta
     3241 agtccaaata aaaacatatt ttctttacca acctgttcac atatctctac atttgcgccg
     3301 tcaagtgtag ccaaagttat agcaccattc atcataaact tcatattact tgttccagat
     3361 gcttccttag ttgtagttga aatttgctca ctaacatttg ctgctggtat tattatttct
     3421 gctaatgata ctccataatt ctctaaaaat actactttta acttgtcctt tactctaaca
     3481 tcattattta tagtacttgc aacagaattt ataaatttaa ttatacattt agccaaataa
     3541 tatcctggtg ctgcttttgc accaaatata aaagttcttg ggtcaagatt caaattagga
     3601 ttatcaagta attcatgata catatgaagt acattaaata tattcagtaa ctgtctttta
     3661 tacgcatgca atctcttaac ttgaacatca aatatcgaac ttgggtctac atttaaatcg
     3721 tatttatctt ttataaactt tgctagattt gctttattat tgtattttat atcatcaagt
     3781 ctttgtaaaa cagaggaatc atttttaaat ttttcaatat tttttaattg taaggtatcc
     3841 ttcttccatg aatcaccaat taaatctgta attaaattgc taagttgagg atttgaactt
     3901 ataagccatc gcctatgtgc aattccatta gtcttattat taaatttatt tggttcatct
     3961 tgatagaaat cttttaatac ctctgtttca agaatatgag tatgaagctt agcaactcca
     4021 tttacactat gacttgtgac aatacataag tttgccatat tgatattgtc acagtctatt
     4081 atactcattc tttttattct atcctgctca tatcctttat tatttaattc ctctacatat
     4141 cttctattta tttcttctat tatcatataa attcttggta atagttcttt catcatactt
     4201 acaggccatt tttccattgc ttctgacatt atagtatgat tagtatagga cactgttttt
     4261 ttagttattt cccatgcttc atcccaagat aaattttctt catcaagcaa aattctcata
     4321 agttctggta tgcataaggt aggatgtgta tcatttatat gaattgctac cttatcgaat
     4381 aaattatcaa tatttaattt gttcttttta tattttctta ttatatcttg tatccctgca
     4441 cttacaaaaa agtattcttg tttcaacctc aacaacttac ctgcatagtt tgaatcatca
     4501 ggatataata cctgtgatat ttcctcagta taatacttat gttttaaagc ctcttcatag
     4561 ctaccagaat aatttagagc atttgaggta agttcaccaa aatctctctt tggtatttca
     4621 ctcttaaaca atcttaaagt atttatacat tggttttggt atccgattat tggtatatca
     4681 taaggcattg ccattacagg aaggtagttt ttatgaatta cttttaaatg actaccttcc
     4741 ttgattaatt ctacctcacc accaaacttc accattgttg cttcatttgg tcttacagtt
     4801 tcccatgcat atcgtccttc tgtaagccag ttatcaggca cttctacctg ataaccattt
     4861 acaaattttt gttcaaacag accatattta taccttattc catatccttg accacttatg
     4921 ttcaaagatg ccatagaatc taaaaagcaa gctgctaatc taccaagtcc accatttcct
     4981 aaggctgggt ctacttcagc ttcaattaaa tcatccaagt tgattcctaa ttcagataaa
     5041 ccttctctaa cttcttcttc aatatttaaa tttaataaat tagattttaa ctgtctccct
     5101 attaaaaatt ctaaactaaa ataataaact tcttttttct tatctaactt tgtagcaacc
     5161 catttttttg ctatctcatc tttcaataga ctacataata catttaacaa ttgttcatca
     5221 gtagcttcct tgatagattg tgcatataag ctatacattt ttacttcaaa tttttgcttg
     5281 aatttctttt tgcttattgt taccaaaaaa accactcctt taatcacata tgtctctata
     5341 tgtttctata tactccttag ctgatttttt ccaactatta tctgttttca ttgcattttc
     5401 aactaattta atccattttt ctttgtcctt aaatactttg attgcatttt tcaaacagaa
     5461 aaacatctca tgagcattgt aatttttaaa actaaatcca ttgccttctc cagtaaattt
     5521 attataaggt gttactgtat ctctaagccc tccagtctct ctaactattg gtaaagaacc
     5581 atatctcata gctaacattt gacctatacc acaaggctca aataatgatg gcattaagaa
     5641 catatcactt gcagcatata tctgttgagc caatgatgca ttaaaagtaa ttctagctga
     5701 tactttatct gaaaaattag aatcgtaata gttgaacatt gattgatatt gatgttctcc
     5761 agttcctaaa acgacaatct gtaaatcttc tctcataagt tctggcatca tgtatgctat
     5821 taaatcaaat cctttttgag aaactaatct cgaaactata cctatcaacg gaatagatga
     5881 atctttttta agtcccaata tatcttgtaa tctcaattta ttttctactt ttttgtcaat
     5941 tgagtctaca tcataatgaa caaatatatc tttatctttt gcagggtcgt ttaaatcata
     6001 atctatacca tttaatatac cttttaattt tcctgactct tttctaagta atccatctaa
     6061 ttgttcacca taaaaagatg tttgtatttc atttgcataa gtaggactaa cagttataat
     6121 tttatctgca aaatttatac cagctttcat aaaatttatt gagccataat actctatatc
     6181 tctattatca aagtattttt gtggtaagtc caatatatca tataaaacat gcttatcaaa
     6241 tacaccttga tattggagat tatgtatagt atacatagtt tttatatttt tatacccctc
     6301 aagggttgca tatctttctt ttagaattaa tggtaacatc cctgtatgcc aatcatttat
     6361 atgtattaca tctggataaa aatcaattct acttatagct tctaaaactg catctgtaaa
     6421 gaaagtatat ctttctgcat catctccata tccatagata ctctttcttt catcttctct
     6481 tctaaaataa aattcattat ctataaagta aaattttaca ccatccaatt ccatttctaa
     6541 aagaccacag tattgatttc tccatccaac acgtacacta aacacagcta tttcttttag
     6601 ttgatctttt aaataacttg gtatagttga atatttgggc attattaccc ttacatctac
     6661 accttctttt tttaattctt taggcaatgc ataagaaaca tctcctaatc ctccagtttt
     6721 tgcaaagggc caacactctg ctgttacata aaaaaccttc attagtcatt cccccttcta
     6781 aaaaatttat ttatatattt gtattctttt ccactacaag aggatatttt tcatctcctc
     6841 ttaattcttt cccatttgat acactcgtat ttttatctaa tattgcatta tatagttttg
     6901 catttgactt tattacacaa ttttgcatta ctattgagtt ctctataact gttccttttt
     6961 caacatttac ctttctaaat atgatactat cttttacagt accttctatt aaacaaccag
     7021 atgctataaa gctattttct actttagcac tatctgtata aattgtaggt gattcattct
     7081 tttcttttgt aaatatcttt ctttcagagt ataataattc atctgcaact tctaaattta
     7141 ataaatcttt gctcatttca aaatatgatt caacagaatt tacacatttt agatatcctg
     7201 tatattcata agctcctatt ttcatatttt ctgcttcttc aataataaat tcttctaaat
     7261 aacaataact gcctttattt acaatgttat atatacattc aacaaaatct tcacgcttca
     7321 taatatatgt ctccatacat atgtttgctc tagggaattt gcctaaatta tttcctacat
     7381 ttattaccct attgttacta tctaaattta gtgttaagtt accagcaaaa tctttatttg
     7441 cattatttac atttttatat attatagtta tatcattatg agatttttta tggtattcca
     7501 atgcttgaga ataatttaaa ttgcatagca tatagcttgg agctattaaa atatattctt
     7561 cttcactctt ttctatataa tctagattag ctaagatagt atatatatca ccttctctat
     7621 gtgagtaagt atttctatac ttagtgtttt ctggactaaa aattgatagg ccaccttttt
     7681 ttctacttaa atcccaatct ttaccactac ctatatggtc tgtcaatgat ctgtattttt
     7741 cttttgcgaa tattccaact ttagtgattc ctgaatttat catattagat aaagcaaagt
     7801 ctattattct atatcttcca gctattggtg tagatgctat tggtcttcca tagttaagtt
     7861 tgtttattgc tgggtctcct tttttgttta aatttattat ccctaaacat tcatttctca
     7921 tcttaaagac ctccttctat taatacgcat ctaggttcga tattttcata ctcagaaact
     7981 acatttattt cattatttac attctttatc tgaacattat catttatagt tgcacactca
     8041 cctatcatag ctttttctat agttacattt tcacctatta caacatttgg cattattact
     8101 gaatcaatta ctttacttcc tttaccaaca acaactccat gtgataatac agagttgcct
     8161 acttcaccta aaattctaca accatcagct atcattgatc tatgaacatt tgcattttta
     8221 cctatatatt gtggaggcat tgccatagta tttgtatata tcttccattt agggtctgct
     8281 aaatcaagtg tttctggaga ttttattata tccatattag catcccatag actttgtata
     8341 gttcctacat ctctccagta tcctttaaat ggataagcat acattccaac attatcttct
     8401 aacattttag gtattaaatt ttttccaaaa tcatcataat ttatttctgg atttttttct
     8461 gcttccttaa aataatttct caacattttc caatcaaata tgtatactcc catagatgcc
     8521 aaattgctct taggttcact tggtttttct tcaaattcat agatacttga atcttcattt
     8581 gtattcatta tcccaaatct tgaagcttca tcccaaggaa cttcaatcac tgctattgta
     8641 gctttagagc gtttttcctt atgaaatttt aacattttgc tataatccat cttgtatata
     8701 tggtcaccag ataatatcaa tacatattct ggattatagg tatctacaaa gtccatattt
     8761 tgatatatcg catgtgctgt accattatac caatttcctt ctttttcatt cataaatggt
     8821 tgtaaaacat agacaccacc atttattctg tccaaatccc aatgacttcc catgcctata
     8881 tgtgaattta atatcaacgg tctatattga gttaaaacac ctacagtatc aataccagag
     8941 tttgaacaat tacttaacac aaaatctata attctatact tacctccaaa tgatacagct
     9001 ggtttggcaa ttctttttgt aaaaacacct aatcttgaac cttgccctcc tgccaaaatc
     9061 atagctaaca tctctttttt catttaatga cactcccctc atctagtaat taatatttat
     9121 aattgcattt ttacttttat aaactttatc agtcaataaa tgccgtgtat aaatgttgct
     9181 taaataatac cttaataaaa ataaaataat atcaactata caattgatat aatgtatacc
     9241 ccataatgaa cttaccgacg tatacattat tttccataag cactatagta tttattaata
     9301 ttcaattatc ggttaaaaaa taatacaaat tttattttat aaatataaaa acatttttta
     9361 taaatccctt gtgtcatata aacatgctta ttttttaatt tgttaaattc gtaatagcaa
     9421 aatataatct aatatttgtt aaataattat ccaaagaaaa tcaagtaatt attaatcaac
     9481 tttatttttt aattgatact tctttgtcta taatttaaac aaaaggatat aaactttt
//
LOCUS       DAMJWO010000109         9417 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.113, whole genome shotgun sequence.
ACCESSION   DAMJWO010000109 DAMJWO010000000
VERSION     DAMJWO010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9417
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.113"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(384..1787)
                     /locus_tag="PC366_003293"
     CDS             complement(384..1787)
                     /locus_tag="PC366_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2578780.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEICYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
     gene            2664..3173
                     /locus_tag="PC366_003294"
     CDS             2664..3173
                     /locus_tag="PC366_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009528606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HDF2578781.1"
                     /translation="MSKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLD
                     LVQISPNANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTK
                     ANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
                     MVVIIDPKK"
     gene            3201..3395
                     /gene="rpmI"
                     /locus_tag="PC366_003295"
     CDS             3201..3395
                     /gene="rpmI"
                     /locus_tag="PC366_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HDF2578782.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAFKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            3451..3807
                     /gene="rplT"
                     /locus_tag="PC366_003296"
     CDS             3451..3807
                     /gene="rplT"
                     /locus_tag="PC366_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HDF2578783.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGIEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            4117..4662
                     /locus_tag="PC366_003297"
     CDS             4117..4662
                     /locus_tag="PC366_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578784.1"
                     /translation="MNEKLMDCFVNPIKCKLLLEVFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKEGSGFSVCPVYASIDEIVEVSKKIASILEPLRNNSHE
                     EGRRMHSIGVIITPPKEDEGK"
     gene            4649..4822
                     /locus_tag="PC366_003298"
     CDS             4649..4822
                     /locus_tag="PC366_003298"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578785.1"
                     /translation="MKGNKSDLHEVEPIYTENRFMIYICIQSKVSLHGLYFIVPFHPM
                     TWSGTMKFFNFSY"
     gene            5098..7023
                     /locus_tag="PC366_003299"
     CDS             5098..7023
                     /locus_tag="PC366_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2578786.1"
                     /translation="MKIKFVIMPLVIFLIVLFVGCQSTKDTEVKAKDTEIKILGTGDL
                     HSILTDSMVSYVNEEREKNKNLLMVDAGDFYGTQSREMWEWSSGKKLINIKRNGRAEY
                     DDIIKSSKDEVPIVKDMAKLKYDAVVLGDNEFISNDKQSLDKLVSDFKNNNMPLVSAN
                     IYEQSGENYVQPYVMKNIKTDEGNVKVGILGLTIKEVGETLGLEDFEKDKKARELGEQ
                     ADYKGKLYANDLVEDAKKWIKVMEKESPDIIVAVVHSGEEPKTDRNPGNRIKELATTV
                     DGIDAIVAGHTHEKIDEHKYKNKSGDEVIVTQPGWHGDRVSEINFKLNKENGKWDIKE
                     KSSKLKIIDKEVSIVATADLHSHFSDKLTVDLVNERSNPIEPVVVDAGDFLDPQTDEM
                     TQWYKEWKSIRDNNSDKTISRCPMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLLD
                     AVIEDFEQVAISVLSANIYRQSGKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKGL
                     KNVNLQEQFQYKDKLYANDLVEDAKKWVKVMKKKKPDIIVAVVHSGEEPKNPKHPGNR
                     IKELATTVDGIDAIVASHTHEKIDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNKE
                     KGSWIINDKFSKTIEVE"
     gene            7424..9328
                     /locus_tag="PC366_003300"
     CDS             7424..9328
                     /locus_tag="PC366_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2578787.1"
                     /translation="MKIKFIIVASIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LISYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLVRFKDGIPEYKKIAEPRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNNIPLVSANVYEQSGEN
                     YVKPYVMKNINTDKGTVKVGILGLTIKEVGERSRFKSFKQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVKVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKV
                     FGKEVNIITTSGLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNTKEMTKWAKEW
                     QYNENKGIYKKINEWPIVYLGYDAVVLGSHEFTEDKETFEGKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDEEDLSSSSLSKDSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
BASE COUNT         3765 a         1046 c         1641 g         2965 t
ORIGIN      
        1 aagtgataga tacctaatta agttgtagat atctgataag aaatttttaa gttttcaatc
       61 gttctaaatt gtgagtataa aaatctacta aatttagtta tgtaaaatat aaattataag
      121 tgtagaaact aggctactag cttttatacc acttcaaaca ttactggaag tagttaagtt
      181 tacagcagtt tagttttatg tagatataat attctgtaaa tagacaaaat taaaatatgt
      241 aattaaaata tgtaagtgtc tcaaaatgaa atttttaatt tatgaggcac ttttttgtat
      301 aaaatcaaat atatttttat aactttaaca ataaaaagag gcttatctct attttgagac
      361 agcctcaaat ttttaaaact atattagttt acagcttctt ttcctatcaa atcttttaac
      421 tcttcatgag tcatagtttc tttttcaaat aagaatttag aaacagaatg taaatcttca
      481 agattatcct ttaacatctc taaagtctct ttataacaaa tttcaactat acgatttgct
      541 tccttttgaa ccttatcaca taagaaagtc ttatcatttc catcaatagt cataaatcct
      601 aagttactca taccatattc acaaaccatt tggttagcta tttcagtgac tttctttaag
      661 tcgtcctttg caccagtaga tttatgatta aatattaatt cttctgaagc ctttccagca
      721 agtaatattt ttatttttcc aatcaactca tccttagtat aaatatatct atcttcatca
      781 ggtaattgaa gaacataacc taatgcttgt cctctaggaa ctatagatat tttttgtata
      841 ggacaaattc ctactatatc acttacaaga gcatgtccag cttcatgata tgctactatt
      901 tttttctctt tttcaaccaa tgcagagttt ttagattcta gccctgcaat aactctttca
      961 agtgccttgt caaaatgttc tgatgtaata cactcactgt catctctaac tgcaaatata
     1021 gctgcttcat ttgctatatt tgaaagatga gccccattga aaccatgagt ttttttagct
     1081 aaaagttcta gatttacaga tttgtctata ggtttgtcat ctgtatgtac ctttagaatt
     1141 tcaaatctag tgtgatagtt tggtgcacct atatgaatgt gtctgtcaaa tcttcctggt
     1201 ctaagtaaag cttcatctaa taagtcaagt ctattggtag cacctattat taatacattg
     1261 gaatctttat taaatccatc catttcaact aaaagttggt ttagtgtttg gtctttttcg
     1321 ttgttacttt caagatgtct ctttgctcct acagcatcta tttcgtctat aaatattata
     1381 cttggagctt cttttctagc tttttcaaat agagttctaa ctctttttgc tcccacacct
     1441 acatattttt caacgaactc tgaaccagta acattgaaaa atgatgagtt tgtttcacca
     1501 gctacagcag atgcaagtag ggttttacct gttcctggag gaccataaaa taatactcct
     1561 ttaggtattt ttgcacccat tttttgatat ttttgtggtg acttcataaa atcgactatt
     1621 tcaaatagtt cttcttttac ttcgtctaat ccagcaacgt ctctaaatgt agtctttggt
     1681 tttgtagaaa gtgaatcatc tgtttgatta tctctttcca tttttgtctg tgcaaagaca
     1741 ggagctggat tgttgatttt cttaaaaaag ttgtttagca ttttcatatt cacacctcag
     1801 gtaattaatt attgttaatc aattttatat tttccatatt tactattttt tattatttat
     1861 ttttcatgga aaaaatatac atgttatcta aataaaaata aatttgtaag atgtatgaaa
     1921 aaatgaattt atgtatatag agatttctac ttatgtattg aataaagtat tacaaattat
     1981 aaattatgta ttgattatat attgagtaaa gtattataaa gcatgtattg attaagtatt
     2041 tattaagtat tgaataaaat attacaaatt tagttgaaat gaaaatgata aaaaatgttg
     2101 tgctatattt tacaaatcat ataaatagag aaattgttgt agcacaaagt aataggtagt
     2161 atattagaat ataatatagg atttgttgtg tagtatagta gcatattaga atataatata
     2221 ggatttgtta tgtagtatag tagcatatta gaatataata taggatttgt tatgtatata
     2281 gtagcatatt agaatataat gtaggatttg ttatgtagaa tatatagagt catgtagaat
     2341 ataaatatat aaaaggattt tgggtataaa tttaaaaatt aatagcaaaa tgagtagtat
     2401 agacatataa ttagtagtag gaagtaatta aatttttcct aaacaaaaaa aatagttgca
     2461 aataatttga ttaagtgata tagtaaataa ggtaagaata aaacaaagaa gaagtccgct
     2521 tctcacctta cgccggaggt tagtaaggta aatataagtt aaagcttaat tttaatttaa
     2581 gtttgtttaa atttggtaac ttatattgcg gatgattacg tcatccgctt tttattttat
     2641 aaaaattttg gaggtgtcct acaattagca aagaattagc aatcaatgaa caaataaaag
     2701 ataaggaaat aagagtcctt tcaccaacag gtgaacaact tggagtaatg cctactaaag
     2761 aagctcaagc aatggctaat agcaaaaact tagatttggt tcaaatctcg ccgaatgcga
     2821 atccaccagt atgtaagata atggattatg gaaagtttag atatgagcaa gcgagaaaag
     2881 agaaagaagc taagaaaaaa caaaaaacta tagttgtaaa agaagtaaga cttagaccag
     2941 gtattgaaca aaatgattta aatacgaaag ctaataatgc tataaagttc cttaaaaaag
     3001 gggataaagt caaagttgaa cttagattta gaggaagaga attaggacat aaagacatag
     3061 gtaaagaagt tatgcttaag tttttagata taataaaaga gtttggagaa ccaacaaaag
     3121 cccctgcatt tgagggtaat aatatggttg taattataga tccaaaaaaa tagatgatta
     3181 actgagagga ggaatttgtc atgcctaaaa tgaaaactca tagaggtgca gcaaagagat
     3241 taaagaaaac aggaactgga aagttaaaga gagctaaagc ttttaaaaaa catatattaa
     3301 ctaaaaaatc tgcaaaaact aaaatgaact taagaaaatc aactttagta agtgatggag
     3361 atgccaagag aatagcacaa ttattaccat actaagatac agattgtaaa taataactat
     3421 agaagaggga tataaaagga ggtcataacg atggcaagag ttaaaaaagc tatgaacgct
     3481 cgtaaaaagc ataagaaaat attaaaactt gcaaaaggat tcagaggatc tagaagcaaa
     3541 ttatatagac cagcaaatac attcgtaatg aaagcattaa aaaatgctta tataggaaga
     3601 aagttaaaga agagagactt cagaaaactt tggatacaaa gaataaatgc agctgctaga
     3661 atgaatggaa tatcttattc aagattaatg aatggattaa aattatctgg tattgaagtt
     3721 aacagaaaaa tgttatctga aatggctata caagacccag aaggatttgc aaaattagca
     3781 gaagttgcta aagcaaaatt agcttagtat tgaatcatga gatgtaaagt ctttgagtta
     3841 tataaataat tcaaggactt ttttattttt tgaaaaatac ttattagtgt catgtacaac
     3901 caattttata atgataaata aaataagcaa tacaatagaa ttttatgaga tttattataa
     3961 gaattgttac aattatttat catagctata aaaagtcata gtaaaaatga tattgatgta
     4021 tgtttatata tgtataaagc tttcaatcaa tcttgaatta atattatcaa catgataata
     4081 ttatcttatt aataatataa ataaggggga gataatatga atgagaaact aatggattgt
     4141 tttgtaaacc caattaaatg caagttattg cttgaagttt tttcaaataa tcgaactaca
     4201 gctaaacaat taggagaaaa atttcaagat atatcaaagg caacacttta tcgttacctt
     4261 aataaaatgt tgaaagatga tattataaaa gtggttgaag aaaataaaat aaggggaact
     4321 gttgaaaaag tatatgctat gaagttagat atagctgatg atgtgaacaa aattatagat
     4381 gagaactctg gagaagaata tgctcaactg tttactcaat atatgatggg atttttaaga
     4441 gaattttatg aatacgctga aagaaaggaa aaggatatcc taaaagaggg ttcaggattt
     4501 tctgtctgtc cagtatatgc tagtattgat gaaatagttg aagtgagtaa aaaaattgct
     4561 agtatactag aacctctaag aaataactcg cacgaagaag gcagaagaat gcattctata
     4621 ggagtgataa tcactccacc taaagaggat gaagggaaat aaatctgatt tacatgaggt
     4681 agagccaatt tacacggaaa atcgttttat gatttacata tgtatccaga gcaaagtatc
     4741 tctgcatgga ttgtacttca ttgtaccatt tcatccaatg acttggagtg gaacaatgaa
     4801 gttttttaat ttttcatatt aatgcctaaa gaaatgaact ttagaccaca tatgcaatta
     4861 ggctacatta tacaattaga ccagatatac agaataaaaa ttagtatttt tatagcagat
     4921 aaattgactg ttattcttct taaaaatcat ctattagtta ttgttagcat attgaaagaa
     4981 attatagtaa tccattgaat aaatgaatat tgcccataat catataaact gctatagttt
     5041 aaaataaagc aggacgttaa attttatagt aatcttaaaa tttaagaggg ggattttatg
     5101 aaaataaaat ttgttattat gccattggtg atatttttaa tagtattatt tgtggggtgt
     5161 caaagtacaa aagatacaga agttaaagca aaagatacag aaattaaaat attaggtaca
     5221 ggtgatttgc attcaatttt gacagactct atggtttcat atgtaaatga ggaaagggaa
     5281 aagaataaaa atctgcttat ggtagatgcg ggagatttct atggtacaca aagtagagaa
     5341 atgtgggaat ggtcttctgg aaaaaagtta attaatatta aaagaaatgg tagagcagag
     5401 tatgatgaca taattaaaag tagtaaagat gaagtaccta tagttaaaga tatggcaaag
     5461 ttgaaatatg atgctgtagt tttgggagat aatgaattta tttcaaatga taagcaaagt
     5521 cttgataaac tagtttctga ttttaaaaat aataatatgc cattggtatc agcaaatata
     5581 tatgaacaat ctggagaaaa ttatgtacaa ccatatgtaa tgaaaaatat taagacagat
     5641 gagggcaatg taaaagttgg aatactaggt cttactataa aagaagtagg ggaaaccctt
     5701 ggtcttgagg attttgaaaa ggataaaaaa gctagagagc ttggagaaca agctgattac
     5761 aaaggaaaat tatatgcaaa tgatttagta gaagatgcaa agaaatggat aaaagttatg
     5821 gaaaaagaaa gtccagacat aatagttgca gttgtacact caggggaaga acctaaaaca
     5881 gatagaaatc caggaaatag aataaaagag ttagcaacta cagtggatgg aatagatgca
     5941 attgtagctg gtcatactca tgaaaaaata gatgaacaca aatataaaaa taaatctgga
     6001 gatgaagtaa ttgttacaca accaggttgg catggagata gagtatcaga gattaatttc
     6061 aaattaaata aagagaatgg aaagtgggac ataaaggaaa agtctagtaa attaaaaata
     6121 attgataaag aagtaagtat agttgctact gcagatttac attcacattt ctctgataaa
     6181 ttaacagttg accttgttaa tgaacgtagt aacccaattg aacctgttgt agtagatgca
     6241 ggcgacttct tagaccctca aacagatgaa atgactcaat ggtataaaga gtggaaaagt
     6301 ataagagata ataatagtga taaaacgatt agtagatgcc caatggtcat ggatatgaat
     6361 cagggaatgt atgatgcagt agtacttgga aatcatgaat ttgtatctga aaaagatgaa
     6421 ttttggtcag atgaacgcct tttagatgct gttatagagg attttgaaca ggtggcaatt
     6481 tctgtgttat cagcaaatat atataggcaa tctggtaaaa attatgttaa accatatatt
     6541 ataaaagatg tggagacgag tgaaggtaat gtaaaagtag gaatattggg acttactata
     6601 aaagaagtag gtaaaggtct taaaaatgta aacttacaag agcaatttca atataaggat
     6661 aaattgtatg caaatgattt agtggaagat gcaaagaaat gggtaaaagt tatgaaaaag
     6721 aaaaaaccag atataatagt tgcagttgta cattcaggag aagaaccaaa aaatccaaaa
     6781 cacccaggaa atagaataaa agagctagca actacagtag atggtattga tgcaattgtt
     6841 gctagtcata ctcatgaaaa aatagatgag catgaatata aaaataagtc tggagaaaaa
     6901 gttatagtga cacaaccagg tgagcatggt aaatattatt ctaaaattac ctttaaagta
     6961 aataaagaaa agggttcgtg gattattaat gataaattca gtaaaacaat tgaggttgaa
     7021 taactttata aaatttatag ataaagtaaa ttatctgata ttgacatgat atataagata
     7081 aagtttctaa tattagtata atgcataatg tgaaatattt taataataag agaataaaca
     7141 agacaaataa aaatatttta acatgtaaga tatagtatga actattatac taatgcttac
     7201 tttataattt gaacatgtta gaataagtct tatttgaaaa ttttagtgta ttagagtaag
     7261 tattatttta ccagtaaaaa atattgagaa ctatatgtag atttgcttaa aaaggaattt
     7321 acatatagtt cttttcgtat aataaatagt acaatcttat atggtaaaga taaagtgtga
     7381 tattaaattt tattatcatc caaaatctaa ggaggagtct cttatgaaaa taaaatttat
     7441 tatagtagca tcaataatat ttttaatagt attacttgtg gggtgtcaaa gtactaaaga
     7501 cacagaaatc aatgtactcg ccacaagtga tttacattca attattccag ataatttaat
     7561 ttcctatgta gaagaggaga gaaaatatga tgagaatcta cttatggtag atgcaggaga
     7621 tttttttgac atgcaaagtg gtgagatgaa taagtggttt actggtcaaa aattagtaag
     7681 atttaaagat gggataccag agtacaaaaa aatagctgaa ccacgtgaag gagaagttcc
     7741 attggctaaa aaaatggcaa agctgaagta tgatgcagtt acatttggga atcatgaatt
     7801 tgtatctaat gacaagcaga gccttgataa attggtttct gattttaaaa ataacaatat
     7861 accattagta tcagcaaacg tatatgaaca atctggagaa aactacgtaa agccatatgt
     7921 aatgaaaaat ataaatactg acaagggaac tgtaaaggtt ggtatacttg gtctgactat
     7981 aaaagaagta ggggaacgtt caaggtttaa aagttttaaa caagataaaa aggctagaga
     8041 acttggggaa caacctcaat acaaagggaa attatatgca aatgatttag tagaagatgc
     8101 aaataagtgg gtaaaggtta tggaaaaaaa agaaaagcca gatataatag ttgccattgt
     8161 acattcaggt gaagagccaa aaaatcctaa aaatccagga aatagaataa aagaactagc
     8221 aacaactgta gagggaatag atgctattgt agcaggtcat acacatgaaa aaatagaaca
     8281 gcatacatat aaaaataatt ctggtgaaga agtaatagta acacagcctg gagctcatgg
     8341 taatagtata tcaaagatta attttaagtt ggataagaag aatgataagt ggtttataaa
     8401 agacaaatat agtgaattaa aggtttttgg aaaggaagta aatataatta caacttctgg
     8461 tctgaatcca aaattttcag atgaaatggc agttaatttg tttaatgaaa gagatagaga
     8521 tgttcaacct atctttatag atactggaga ttttttaaat actaatacaa aagaaatgac
     8581 taagtgggct aaagagtggc aatacaatga aaataaaggc atctataaaa aaataaatga
     8641 atggccaatt gtatatcttg gttatgatgc tgtagtactt ggtagccatg aatttacaga
     8701 ggataaagag acttttgagg gaaaaaaatc tacattggat tatattatag aaaactttga
     8761 agaaatgaag ataccagtat tatcagctaa tatatatgat gaatctggag aaaattatgt
     8821 aaaaccttat ataattcata atgtagaaac tagggaagga aatataaagg ttggagtatt
     8881 aggtcttact actactgata aggatgaaga agacttaagt agctcaagct taagcaaaga
     8941 ctcaaagact tcgaaaattc ctgaagaaac aggaaagtta tatactaata atctagtaaa
     9001 agatgcaagc gaatgggtaa aagttatgca aaaggaaagt cctgatgtga ttgttgcagt
     9061 tgtacattca gataataata gtactctaaa aaatccaagt agtgaagtca aaaaacttgc
     9121 aatgtcagta gatggaatag atgctattgt tgtaggtcat acgaaaaata aggtagaaga
     9181 acatatttac aaaaataagt ctggagatga ggttatagta acacaatctg gagaagattg
     9241 ttattcaaaa ataagtcttg aactaagaaa agaaaatggc aagtggaata tcataaacaa
     9301 atatagtaaa gcaataaaaa tgaagtgaat ttattgatat ataaaccatt attaacactg
     9361 atttttataa tataataaat actgattcta caatataatt aacactactt ttttaaa
//
LOCUS       DAMJWO010000110         9134 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.114, whole genome shotgun sequence.
ACCESSION   DAMJWO010000110 DAMJWO010000000
VERSION     DAMJWO010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9134
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.114"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            207..1412
                     /locus_tag="PC366_003301"
     CDS             207..1412
                     /locus_tag="PC366_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDF2578788.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVGPSKIRTFGIPVEKSFLSHRDKD
                     IVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIE
                     KKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNVKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1483..1704)
                     /locus_tag="PC366_003302"
     CDS             complement(1483..1704)
                     /locus_tag="PC366_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578789.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(1845..2444)
                     /gene="recR"
                     /locus_tag="PC366_003303"
     CDS             complement(1845..2444)
                     /gene="recR"
                     /locus_tag="PC366_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012634696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HDF2578790.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2457..2807)
                     /locus_tag="PC366_003304"
     CDS             complement(2457..2807)
                     /locus_tag="PC366_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HDF2578791.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(2866..4503)
                     /gene="dnaX"
                     /locus_tag="PC366_003305"
     CDS             complement(2866..4503)
                     /gene="dnaX"
                     /locus_tag="PC366_003305"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HDF2578792.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKYSIDENESK"
     gene            complement(4580..4844)
                     /gene="ffs"
                     /locus_tag="PC366_003306"
     ncRNA           complement(4580..4844)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="PC366_003306"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(4882..4973)
                     /locus_tag="PC366_003307"
     tRNA            complement(4882..4973)
                     /locus_tag="PC366_003307"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4937..4939),aa:Ser,seq:gga)
     gene            complement(4974..5429)
                     /locus_tag="PC366_003308"
     CDS             complement(4974..5429)
                     /locus_tag="PC366_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HDF2578793.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(5749..7020)
                     /gene="serS"
                     /locus_tag="PC366_003309"
     CDS             complement(5749..7020)
                     /gene="serS"
                     /locus_tag="PC366_003309"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDF2578794.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKKIPQLIKEGKDVTEEKTRLKELSDKIKGIDEKVKEVEAKMEYTLM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEYKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIK"
     misc_binding    complement(7145..7351)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7478..8359)
                     /locus_tag="PC366_003310"
     CDS             complement(7478..8359)
                     /locus_tag="PC366_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HDF2578795.1"
                     /translation="MNFLSLAKAASTNSNITKRTLENMLNNFSDNIPNIIYAIIVFVI
                     GIYISKIVRKMVSRFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGVIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFINEKR
                     ILDDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENNIKVPFVP
                     SSLLFNNMSNSNTMDKR"
     gene            complement(8371..8880)
                     /locus_tag="PC366_003311"
     CDS             complement(8371..8880)
                     /locus_tag="PC366_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HDF2578796.1"
                     /translation="MNSDERRSKLIDILKESKCPVKGGMLAEILNVSRQVIVQDIALI
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHRNSKEIYDELKIIVDLGGIVKDVIVNH
                     PTYGQITAELNIHSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIETLKEETIEVITK
                     ELEDRGILS"
     gene            complement(9007..9123)
                     /gene="rrf"
                     /locus_tag="PC366_003312"
     rRNA            complement(9007..9123)
                     /gene="rrf"
                     /locus_tag="PC366_003312"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         2914 a         1617 c          998 g         3605 t
ORIGIN      
        1 atttaaattt tttatttaca agaatatttt taatataaca tatttgataa aattaattta
       61 catttctttc acttgtaatt tttgcaatct tgtattagat taatattaaa aataatttat
      121 caataacctt attcacaaag acagttttta tatatcaaaa tataatacaa tataaatact
      181 atgctacatt ttaggaggat tttattatga gcaaaaaagt attaataatg tctgcttcca
      241 ctggtggtgg gcataatagg gctgctctag ctattaaaga agaacttact tccaaaacac
      301 ttgatggaga gccaattgaa tgtgaaataa tagatagttt gaaattagtt aataatacaa
      361 tggataaaat aatttcaaga ggatacgaaa aatctgctat atatactccc aaagcctatg
      421 gaagtgtata tagattatct gaaacaaatc ttttgtcaaa aaatgaattt aaagataatc
      481 tactaataac attcatggct aaaaaattta aaaagcttat tagaagcgaa aaaccagact
      541 tgattatagg aacacatcct tttccaatga ttgctctaag cacattgaaa aaaaacttta
      601 atttacataa taatgaatca aatgcttaca cagagcattt ttataaacat tatacaaata
      661 ccattaatgt tcctccgctt atttctgtat taaccgatta tactactcat tctacatgga
      721 tacaaaatga aattgattac tatattgttg gtcatgaata tgtaaaagaa ttattggtgt
      781 ttgatggagt tggaccgagt aaaattagaa catttggaat ccctgttgaa aaatcttttc
      841 tctctcacag agataaagat attgttcttt ctgagttgaa tttatctcct gataaattaa
      901 ctgttttact tatggggggt agctttgggg ctggaaatat aaaagagaca cttgatgaat
      961 tactggatac tgatagagat tttcaaatac ttgtaattac tggtaagaat gaaagcctaa
     1021 aagaaaaaat cgaaaaaaaa cttatgtctc gttatcatga taaaaatgta tgtgttcttg
     1081 gatacactga taagatgaat gatattttag cttctataga tgtattagta agcaaacctg
     1141 gtggacttac tacaactgag gctcttttaa aagatgtacc tatgatagtt ccttattata
     1201 taccaggtca ggaagaagag aatcttgatt tcttatctaa ttgtggtgca gcacttagaa
     1261 ctacaaaaaa atataacttg tcaatattac taaaagttct aatagatgac cctagcagat
     1321 tagaaatgct aaaaagaaat gttaaatcaa taagaaagtc aaattcagcc caaaatatag
     1381 ctaatttaat tttaaatata atttctggtt gataaaataa ataaaatccc tatagtatat
     1441 atattatcta ttagggattt tttattttct aattatttaa tattaaattg gttcataaaa
     1501 gtcttcttca taatcatact gataattttt ataattattt ctaaattcag catttttatt
     1561 tcgtacattt tttttagttt ttttcttatt agaaaaactt atatcctcaa aatcatcata
     1621 tttaggttta tcttttgatt tcattttttt aactcttttt tctttcattg cattatgttc
     1681 ttctaagttc ataattggtt tcatgttgca cccctatcaa aatttttaaa tgatttatac
     1741 aacaaattat acaatacaga agaaatttat tcaataaatc taaatcaaaa ttaatttgaa
     1801 tttaactcaa aaaactacaa aaatcgaggt attaacctcg atttttatat ttctcttctg
     1861 ccttctagtg cttttgatat tgtgacctca tctgcatact ctaaatcgcc tccaacagga
     1921 agaccatgag ctatccgagt gactttgatt cccattggtt ttactaacct agcaatatac
     1981 atggctgtcg cttcaccttc aatagtagga tttgttgcca ttattatttc tttgacttcc
     2041 tgattgccaa gtctttggat aagttccttt atttttaaca tatctggtcc aattccatcc
     2101 attggagaaa ttactccatt taatacatga tactgtcctt taaactctct cgttctctcc
     2161 atagctgcta catctcttgg atcttccaca acacatataa cacttgaatc tctactttta
     2221 tttgaacaca tgctacatgg gtctgtatct gttatattac aacaaattga gcaatatctt
     2281 atttctcttt ttgcatctat aatcgcttta gataaagctt ccacatcatt agtattcata
     2341 ttaataatat gaaaagccaa tctttgagca gtctttcttc ctactccagg aagctttgaa
     2401 aattcctcta taagtctcgt tatgggacct gtataaactt gcataaatac cacctactag
     2461 aataacccag gtatattcat acctccagtt accttactca tttgacttgc ttgtatatca
     2521 tcaatatttc tcaatgcttg atttactgca cttaaaacta aatcttgtag catttctata
     2581 tcatctggat caactacttc tggcttgata gttatatcta taacttcttt tttaccatta
     2641 acttttacag taactgctcc tccaccaact gaagcttcta cttctttact ttctaactct
     2701 tgttgagctt tttgcatatt ttcttgcatt ttttgagcct gctttaacaa gttgttcata
     2761 tttccaccac caggcatcat tccgcctcca aaaccttttt tagccataaa cactattcct
     2821 cctaaactta ttttcatttt attattatat cataatagta ttttattatt tactctcatt
     2881 ttcatcaata ctatatttta tttctaatat ctcttcactc actatgttct ttaatatctc
     2941 ctcaccaatg tcctttttct ctttaacttc aagatttata tctttaactt ctgatgtcag
     3001 tactattttt acattaaaac ttctatttaa aacatctctt attgtttttt ctaaataatt
     3061 tattgtatct tgagagctca gtctagtttt tgcaaaatca aatttatcat caaatataac
     3121 atacaacata ttagaatata cattaaaact ttttacttca cttaagagtg cgtatattgg
     3181 cattttttta tcttttttaa tttgtttaag tatattcttc caagatgact ctataagtat
     3241 aacgtcctca ttttttacat cttcataaac tacattttct tgttttacat ctatttctct
     3301 atcgacctca tactcttttt ctttattatt cccaattttt tcagacttaa agttccccag
     3361 ttcaatcatt ttttctaagt tctcaactct ttttataaga gcttctttac tttcatcaaa
     3421 cattggttga gcaattttca ttatggttat ttccactaaa acccttggat ttgaagatga
     3481 ctttatatca tcctgagtta ttgataatat atttaaaatc cttattaaat catttatatc
     3541 tatattttta gactgaattt taagttgttc tatagtttct tctggtaatg aaattatttc
     3601 atccaattct gatgaaacct tacataccat taaatttcta aaatgatcaa ttaagtcatt
     3661 tataagattt cttatatctt tgccccataa gacaaattca tttaatatct caagagactt
     3721 tttagtgtcc tgctctacaa tacattgaga caattcaaat aattgttcta tatttacgct
     3781 tcccattaat tcaacaacat ctttataatc tatcttactt tctccaaaag acatacattg
     3841 gtctaatata ctaagtgcat ctctaagagc tccttgagaa tttctagcta ttaaattaag
     3901 agctttatca tctatatcaa ttccttcatc ttcacaaatc tttttcattc taagggtcat
     3961 atctttaact gtaactcttt taaaatcgta tctttggcat cttgataaaa tggttgcagg
     4021 tattttgtga ggctctgtag ttgctaatat aaaaattaca tatgatggag gttcctctaa
     4081 ggtctttaat aatgcattaa aagctccttg agacaacata tgaacttcat ctattatata
     4141 tactttatat ttagcattgg ctggagaata tttcacactt tctctaagct ctcttatatc
     4201 atctacacta ttatttgaag ctgcatctat ttctacaaca tccattgtat tatcttttaa
     4261 tacagattca catatctcac actcattaca cggttcttca tttattttat tcaaacagtt
     4321 tactgctctt gaaaaaatct ttgcagtaga tgttttacca gtacctcttg ttccacaaaa
     4381 caaataagca tgtcctatat tatcactata tatttgattt tttaaagtct taataatatg
     4441 atcttgacca ataacatctt caaatttttg tggtctatat gctctatata atgctttatg
     4501 catcttttta cctctcttta gcaaaattaa taaaaaaatc cctcattatc taagggatta
     4561 gtcttttata tattaaatgc tgtacaccat ctatcgactt aattccatag gcgttaccaa
     4621 aacagttagc tcaacttagg cacccccacg gcacacaaaa gtgatcactt accgctgctt
     4681 ccttccggat ctgacggggt tcatgagctt tcattgcgca ggacctaagc atcaacacca
     4741 cttatttagg gcggccctac agaaaataag cctttagatg gaattcaatc ctgctatagc
     4801 ggattgcagg ttacagggca ccgctacctc cccatctagt acagcaaaat tacaaccata
     4861 tttaattact ttcattgttt ctggcggaga gagtgggatt tgaacccacg atacagtttt
     4921 acccatatac tcgctttcca ggcgagcgcc ttcgaccact cgaccatctc tccttaatct
     4981 ctttttctca atgccttaaa aaattcttgc aatatgatcg agcattcttc ttgcaaaaca
     5041 tcaaaagcta cttttacatt attattatta aaataatcta atttaaactc atgctgtttt
     5101 tctatatatg aattttttac atgtcttgtc cctattataa gcttttttat tctagaatta
     5161 actattgcgc cactacacat tatgcaaggt tccattgtaa catataaatc acaatcagtc
     5221 aacctccaac cacctaattt ttctgatgct tgttttatcg ctaaaatttc tgcatgtgcc
     5281 gtagagtctt ttaacgtttc tgtaaggtta tgagctctag ctattatttg attatcttta
     5341 actataatag cacctattgg tgtttctttt ttattatatg ctttatatgc ttcttttaat
     5401 gcttctttca tataaaatga actttccata attcctccca aaacttataa caaacttatc
     5461 ttatcataat tcattttata attcaactta attttatttt gtttatttaa ttattactat
     5521 atatagcgat atttttttta attagttcta aaataatttt tagatattca tacaagagtg
     5581 ttttataaaa atatttagtg ttttatgatg aaaattctgc tgtgtaaatt aacataaaaa
     5641 aactatgaaa ttaatattta taataatttc atagtttttt tatttattgt ttactcataa
     5701 tatattctct tcatcaaagc atactctaca tatacaatta atataaattt attttataac
     5761 atcaacaccc atataaggtc ttaattcttc tggaactact acagaaccat ctgcctgctg
     5821 ataattttct aatatagcag ccaaacatct tcctatcgct aatccagaac catttaatgt
     5881 atgaacatat tctgcttttg attttttatc tcttttaaat cttattcctg ctcttcttgc
     5941 ttggaaatct tcaaaatttg aacaagaaga tatttctaca tatctattgt aacttggcat
     6001 ccaaacttct aaatcatatt taaatgcagc tgtaaatccc aaatctcctg tacatatttt
     6061 tacaactcta tatggaagac ctaacatttg taacatagtt tcagcatcat gagttaatga
     6121 ttctaattca ttataagaat cttctggttt aacaaattta actaattcaa ctttattaaa
     6181 ttgatgttgt ctaactaaac ctcttgtatc tcttcctgct gaacctgctt cagatctaaa
     6241 acaaggagta tatgcacagt atttaattgg aagctctgca acatctaata tttcattagc
     6301 atgtatatta gtaacaggaa cttcagctgt tggtattaag aaatactcta atccttctat
     6361 tttaaacata tcttcttcaa atttaggaag ttgaccagtc cctataaaac tatttctatt
     6421 ggccataaat ggaggtaaga cttctgtata gccatgctta gctgtatgag tatttaaaaa
     6481 gaaattcatt aaagatcttt ctaatctagc tcctaatccc ctatataaag taaaccttga
     6541 cccagttatt ttccctgctc tttcaaaatc taaaatacct agacctgtcc ctatatccca
     6601 atgcgcttta tactcaaaat caaatttagt aggttctccc caagttctta tttgaacatt
     6661 gtcttcatct gtttcacctt gtggtacctc tggatgagga acatttggta ttctcattaa
     6721 tgtatattcc atttttgctt ctacttcttt tactttctca tcaatacctt ttatcttatc
     6781 tgataactct ttcaatcttg tcttttcttc tgttacatct tttccttctt ttattaattg
     6841 aggtattttt ttagaattta catttaactc atttttcata acttcaactt cttgaagtat
     6901 ttctcttctt ttattatcta gttccactac agcatcaagg tcaaattctc tttcacctct
     6961 tctttccata gcttttttga tatcatctag attttctctt attcttttaa tatctaacat
     7021 attaattcct cctaataatt ttgataatat aaattataat tccaattaat ttacaagtat
     7081 tctagctgta aacttttaat ttaaacaaat ttgaaaaata aaaaaagacc tccgtttacc
     7141 ctataaaagg gacgaaaatc ttttatccgc gttgccaccc taattgatta tactaaaacg
     7201 tataatcctc tcagacctat aacgtaggta aaccgtctag ctttaactag aagctctaga
     7261 gtagattcaa aaaccattgt aatgagttct caccatccac tcattctctg aatacaatct
     7321 gttttttact attttccttc accgcttttt aactaattgt tttatttgat aatcattata
     7381 ttatatatat taacatcttt caatactatt attcaaattt ttttagaatt ttctttaatt
     7441 ttttatatta aattcacttt tttacttaat tgaaattcta tcttttatcc attgtatttg
     7501 aattgctcat attattaaat aataacgagg aaggaacaaa tggaactttt atattatttt
     7561 cgtcaaattt atttttgact ttttccatta catcaaagta aacatcccag taatcatcag
     7621 ttttaaccca tggtctagca actatttgca tagtgttgtt tcctatagag tttaaaccta
     7681 taattggttt tgggtcatcc aatatccttt tttcatttat aaaaatttca ttcaatatgg
     7741 acttaactac atcaatatca ctatcatatg aaatattata tgaaaaatct atccttcttt
     7801 tattttgatg tgtgtaatta attatattgt tacttgtcaa ttgaaagttt ggtataatta
     7861 tggttttatt atctggggtt ttaagaacag tactaaatat ttgtatatca gaaactgtgc
     7921 cttctacacc tgagccttga atataatcac ctatattaaa tggcttaaaa aataaaataa
     7981 tcatacctga acctaaattt gataatattt ctttaaatgc taaacctata ctaaatccag
     8041 cagctcctaa tacagctaca actgatgtag tttgtatccc tataacaccc aagcttatca
     8101 atgatataat agataacata gatatgtata ttccatatac aatgaaatta tttacacctt
     8161 tactcattcc atatttgatt aaaaaccttg aaaccatctt tcttactatc ttagatatat
     8221 agatacctat tacaaatacg attattgcat atataatatt tggtatatta tcactaaagt
     8281 tattaagcat attttctaaa gttcttttag ttatattact atttgttgaa gcagccttag
     8341 ctaatgataa aaaattcatt taactcctcc ttatgataat attcctctgt cctctaattc
     8401 ttttgttata acttctatag tctcttcttt taatgtctca attgtatgaa tatgactaca
     8461 ttcagttaga actgataact gtttaaattc atttgtctca accttcttca taaaattatc
     8521 tatatccatt ttagagtgaa tattaagctc tgcagttatc tgaccatatg ttggatgatt
     8581 tacgatgaca tccttaacaa ttccacctaa atctacaata atctttaatt catcataaat
     8641 ttctttagaa ttcctgtgat tcttacattt tatttgcttt gtaaaatatg gttgattata
     8701 tattatatat ccttgaggtg tagctattat ttcaaatcct ctagctctta taagggctat
     8761 atcttgtact attacttgcc tacttacatt taatatctca gctagcattc caccttttac
     8821 agggcactta gattctttta aaatatctat taatttgctt cttctttcat cagaattcat
     8881 attacacctt ctttctaaat caaaaacttt acctatacta tataattcta tattttatct
     8941 tattataaat caatattgat tttatattct atttaatatt aaactttatt gcaaataaaa
     9001 aagattacgt ggctacgtcc tactctccca ggcagtttcc caccaagtac catcagcgct
     9061 agagagctta acttctgtgt tcggaatggg aacaggtgta tcctctctgc tattgtaacc
     9121 acataatctt tatg
//
LOCUS       DAMJWO010000111         9116 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.115, whole genome shotgun sequence.
ACCESSION   DAMJWO010000111 DAMJWO010000000
VERSION     DAMJWO010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9116
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.115"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            51..311
                     /locus_tag="PC366_003313"
     CDS             51..311
                     /locus_tag="PC366_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578797.1"
                     /translation="MFKTVFEDKEYVLLCKNYSKSDGVKAIFIYLISMLLLFFQGYLY
                     TTNLSSTILTNSQMILSILILLIGLGFVLLSKEKLNTIGITM"
     gene            330..758
                     /locus_tag="PC366_003314"
     CDS             330..758
                     /locus_tag="PC366_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2578798.1"
                     /translation="MYGVIGATVLVIFVILTAGIMQGKKVDFQLPTVFMIVTFIVSAI
                     SEEIVFRGYIQTRLTGLIKNSVLSSCINAFLFLSTHYPVKWISSGDFSFAILSGFYVI
                     CLILLNFSCDLVYRKTNCLWGAWLLHILYNIGTGVLIFTT"
     gene            878..1486
                     /locus_tag="PC366_003315"
     CDS             878..1486
                     /locus_tag="PC366_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HDF2578799.1"
                     /translation="MVDNLIKYIHKSNIAIVVLHEIYGVNNFIKDVCQKYYKGGYDVF
                     CPELLGEKRVFSYLKAQEAYDFFINNVKFDIYKKVEKLINGLKSEYKHVFVVGYSIGA
                     TIAWRCSENSLCDGIICCYGSRIRDYMDVIPTCPILLVFAKYDSFDVDYVSSQLSRRQ
                     NIQIEILDANHGFIDTYSKNYSNAQTEVFNIKEKNFLSKCLG"
     gene            2010..2222
                     /locus_tag="PC366_003316"
     CDS             2010..2222
                     /locus_tag="PC366_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2578800.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            2235..2456
                     /locus_tag="PC366_003317"
     CDS             2235..2456
                     /locus_tag="PC366_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2578801.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEVTVRDYELSIRKSDAEKIIVE"
     gene            2556..4712
                     /gene="feoB"
                     /locus_tag="PC366_003318"
     CDS             2556..4712
                     /gene="feoB"
                     /locus_tag="PC366_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF2578802.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTIIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKDAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISSIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKIPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHVPSAKGVLIHM
                     WDRGKAFIIKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVASAFAFMAF
                     NMLCAPCFAAIGAIKREMGSWKWTWITLGFQTLTAYIIALLINQVGSLVLGTGGSIAG
                     AIISIFIAVAVVFVVLTYSNKNMKKEKMGKLSYMKN"
     gene            4738..4890
                     /locus_tag="PC366_003319"
     CDS             4738..4890
                     /locus_tag="PC366_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HDF2578803.1"
                     /translation="MATFIIAAIVVVLMALAVMYMVKNSKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            5070..5780
                     /locus_tag="PC366_003320"
     CDS             5070..5780
                     /locus_tag="PC366_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HDF2578804.1"
                     /translation="MFKFDVTNELMCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPS
                     NGGGLGRALLGHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESE
                     NLLAFSEQLNYSVKLIGSGVISQKGLFTTHLVNKTGQNQDVAIITDGNPLILEGPCCV
                     DPDALVAWTGREPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKT
                     DSTPSDRMSSGGLRLGID"
     gene            5865..6635
                     /locus_tag="PC366_003321"
     CDS             5865..6635
                     /locus_tag="PC366_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2578805.1"
                     /translation="MFEKIHKRFKGYYIFLIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVVFGVNKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SKKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            6628..7359
                     /locus_tag="PC366_003322"
     CDS             6628..7359
                     /locus_tag="PC366_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578806.1"
                     /translation="MVRSGFLLENIYKKYLVDNKEHLVLDNISLNISSEEITVILGES
                     GCGKTTLLRILAGLENATSGNIYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVNIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            7393..8352
                     /locus_tag="PC366_003323"
     CDS             7393..8352
                     /locus_tag="PC366_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2578807.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNDNIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDEVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(8450..9046)
                     /locus_tag="PC366_003324"
     CDS             complement(8450..9046)
                     /locus_tag="PC366_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HDF2578808.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DVNREEKINDIYKYLYKCKKIDFIVIDKEKKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVNKLKSDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
BASE COUNT         3406 a          963 c         1659 g         3088 t
ORIGIN      
        1 gataaaatat gagaaataaa taagaattta attagaaagg agtatttata gtgtttaaaa
       61 ctgtatttga agataaagaa tatgttttat tatgtaagaa ttattctaaa agtgatggag
      121 taaaagcaat atttatttat ttgatatcta tgttactatt gtttttccaa ggttatttgt
      181 atacaacaaa tttaagttca acaattttaa ctaactcaca aatgatattg tcaatcttga
      241 ttttacttat agggctggga tttgtactac tttcgaagga aaaactaaat acgattggga
      301 ttacaatgtg aaatttaaat aaaagtcttt tgtatggagt tattggtgct actgtactcg
      361 taattttcgt tattttaaca gctggaatta tgcaaggaaa aaaagttgat tttcaattac
      421 ctactgtttt tatgattgtt acatttattg tttctgctat ttcagaagaa attgttttta
      481 gagggtatat tcaaacaagg ttaactggat taataaaaaa tagtgtactt tcatcttgta
      541 ttaatgcttt tctttttcta tctacacatt accctgtaaa atggatttca agtggagatt
      601 tttcatttgc aattctatct ggattttatg tgatatgcct tatattactt aacttttcat
      661 gtgatttagt atatcgaaaa actaactgtc tgtggggggc atggctactg catatcttgt
      721 ataacattgg cacaggagtg ctgattttta ctacttagtc aattttactt tgcagaaagt
      781 ttatcgtaag aaacggatta ttttataagt caaattttag agctagtaaa ttgacatact
      841 taaaataatt taaactagat gtaaaaaata tcgacaggtg gtggacaatc tgattaagta
      901 tatacataaa agtaatatag ctattgttgt actgcatgaa atttatggag ttaataattt
      961 tataaaagat gtttgtcaaa agtattataa aggtgggtat gatgtgtttt gtccagaact
     1021 cttaggagaa aaaagagttt tttcatactt aaaagctcaa gaagcatatg atttttttat
     1081 aaataatgtt aagtttgata tttataaaaa agtagaaaaa cttataaatg gtttaaaatc
     1141 ggagtataaa catgtatttg tagttgggta tagtataggt gcaactattg catggagatg
     1201 tagtgaaaac tctttgtgtg atggtataat ttgttgttat ggctcccgaa ttagagatta
     1261 tatggatgta attccaacat gtcctatttt gctagtgttt gcaaaatacg attcattcga
     1321 tgttgattat gtttcttctc aactttctag aaggcaaaat attcaaattg aaattttaga
     1381 cgcaaatcat ggttttattg atacatactc aaaaaactat tctaatgctc aaacagaagt
     1441 ttttaatatt aaagaaaaaa actttctatc taaatgttta ggctaatatg ttttattata
     1501 aaatatagaa aatttaatca atttgaaaaa cataatgaca ctactaatgt taaaaaatat
     1561 tagtagtgtc attatatttt ttgagataga gatagtcagt agaatcatag aattaattat
     1621 gtttttatga ttgtattaga ttaatattta aattacattg aaaagaaaaa aatcattact
     1681 atagaataat atctttatca aaagaacatt cttatgcaga atatggttat gagtatctaa
     1741 gagaaatctc aaaatatata ggatagcagt atgaattttt atagatttta ttaatacaat
     1801 aaatcaaatg agaaaaaaaa tcaaaagaat acaataatca cttgcaaaaa atatgctatt
     1861 gtgatagact taaatcaaaa ttaggaattg taagaataag gaaaaagata agtaattatt
     1921 ttaacgagtc aaaatttaag aaattgtgat ttatatataa gatagaggtt gtttgtaaat
     1981 ttaaattggt tgaagaggag gaatattata tgatgccatt gatattatca aatacaggtg
     2041 aagaagtagt tataaagaaa atttcgggaa gtgataagac gaggactttt ttaaatagta
     2101 taggttttgt agtaggtaca aatgttaaaa tagtttctaa gatagatggt aacttaataa
     2161 tagacgtaaa agatactaga gttgcattag ataaaaaaat ggcaagtaga ataataatat
     2221 agggaggtaa tgacatgaac agactgaagg atattaagtg tggagagact gtaaaagtca
     2281 aaaagttaga aggagaagga gctacacgaa gacgtataat ggatatgggg attacaagag
     2341 gtgttaatat atttataaga aaagtagctc ctcttggtga tccaattgag gtaacagtca
     2401 gagattatga actatcaatt cgtaagtcag atgcagaaaa aattattgtg gaataataaa
     2461 gattaattag agtagggtta atgtaattat ataatgagaa tgattttctg tatcacaaac
     2521 agtgatgtat ttaaataata atggagggaa tggaaatgtc aataaaaata ggtctcatag
     2581 gaaatcctaa ctgtggtaag acaacaatgt tcaatgggct tacaggctcg tcgcaatatg
     2641 ttggtaactg gccaggagta acagttgaaa aaaaaggtgg aaaattaaaa ggaaataaag
     2701 atgtggaaat agtagattta ccaggtattt attctttatc tccatataca ttagaagaag
     2761 tagttacacg taattttatg ctagatgata agccggatgc agtaataaat attgtagacg
     2821 catcaaatat agagagaaat ttatatctta caactcaagt tttagagcta ggtataccga
     2881 ccattatagc tcttaatatg atggatattg taaataagaa tggtgataag ataaatatta
     2941 aagaactatc tgaagttata ggttgcccag tggtagaagt aacagcagtt aaaggtcaag
     3001 gaattatgga ggctgctgaa aaggcagttg aacttgcaag tagtaacaat aaattaaatt
     3061 tcaaattacc ttttgttgat gaaagtaagg acgcaataga aaaaattgaa aaaataatag
     3121 aagaaaagac tccatatata gatgtagaaa cacgctggtt agctataaag ctatttgaga
     3181 gagatgaaaa tgttatacaa aaacttgata tttctaaaac aatattgaat agtattgaag
     3241 aaataactag aaattgtgaa gatgaattgg atgatgatag tgaaagtata ataacagcca
     3301 atcgttatga atttattagt tcaataattt caagtataat aaagaagaat cgaaaaggta
     3361 aggaaactgt atcagataag atagataaga ttgtaacaaa tcgtatacta gcattaccta
     3421 tttttgcact tataatgtgg ggagtttact atatagcagt aagttcattg ggtactatag
     3481 caactgattg gacaaatgat gtactgtttg gagaaattat tcaaggcaat gtaagtaatt
     3541 ttctagcttc tttaaatgta gcagagtggt tacaaggact tgtagttgat ggtctaattg
     3601 gtggagttgg agcagtacta ggatttgtac cacaaatcat gcttttattc ttattattgt
     3661 caatattaga agattgtggg tatatgtcac gtgtagcttt tataatggat agaattttcc
     3721 gtaagtttgg tctttcagga aaatcattta taccaatgct tataagttca ggttgtggag
     3781 ttccaggagt tatgtcaact cgtactatag agaatgatag agatagaaaa atgactatta
     3841 tgttaactac attcattcca tgtggagcta agattccaat aatagcatta tttgcagggg
     3901 cattatttgg aggtgcttca tgggtagctc catcaatgta tttcttaggt attgcaatga
     3961 taatcatttg tggaattata ttaaagaaaa ctagtttatt tgcaggagaa ccatctccat
     4021 ttgttatgga attacctcaa tatcatgttc caagtgcaaa aggtgtttta atacatatgt
     4081 gggatagagg aaaagcattt ataatcaaag caggaacaat tatatttgtt gcttgtggag
     4141 taatctggtt cttacaatca tttaattggt cattacaaat ggtagatgct ggagatagta
     4201 tattagctag cttaggaaat atagttgcac caatatttgc tcctcttgga tttggaaatt
     4261 ggcaatcatc agtagcaaca gttacaggtc tagtagctaa ggaaaatgta gttggaacat
     4321 ttggagtttt atttggtata tcagatgcaa cagagcaaga cccaacactt cttgcttcag
     4381 ttgcaagtat gtttacagta gctagtgcgt ttgcatttat ggcatttaat atgctttgtg
     4441 caccttgttt tgcagctatt ggagccataa aaagagaaat gggttcatgg aaatggacat
     4501 ggattacatt aggattccaa actttaacag cgtatataat tgctcttctt ataaatcaag
     4561 ttggaagttt agttttaggt actggaggaa gtattgctgg ggcaataata tctatattta
     4621 tagcagtagc agtagtcttt gtagttttaa cttattcaaa taaaaatatg aaaaaagaaa
     4681 aaatgggtaa attaagttat atgaaaaatt aattcatata aataaggagt gatgaatatg
     4741 gctacattta ttatagcagc tattgtagta gtattaatgg cactagctgt aatgtatatg
     4801 gttaaaaatt caaaaaagaa tggtagcagt tgtggatgtg gttgttctgg atgctcaagt
     4861 agtaagagtt gtcatagcgc taagagataa ataggataag agcctgataa aaagttaaat
     4921 tgctttatta tcaggttctt attttttata taaataacaa atttcatatt tgaagtaggt
     4981 tagactatgc tgtaatttta ctgtataatt atatataaat atatgattag gagggattat
     5041 tgctaaatta agcaatataa gtgaatatta tgtttaaatt tgatgttaca aacgagctta
     5101 tgtgtatagc aaggggaagt ggtaaatttt ttgcaaaaaa aggtgctatg gtagccttta
     5161 aaggaaattt taattttgaa aaattgctgt taggtccaag taatggcggt ggattgggaa
     5221 gagcattatt aggtcatgtt cagaggtcat tgacaggaga acaaatgcca ataatggtgg
     5281 ttgaaggtga aggtgaaatt tacctagctc aaaatgctta ccatgtagat gtaatatcaa
     5341 ttgacccagg tgattccatt tatgttgaga gtgaaaactt attggcattt tctgaacaat
     5401 taaattacag tgtaaaattg attggttcag gggtaatatc tcaaaaaggt ctttttacta
     5461 cacatttagt aaataaaaca ggtcaaaatc aagatgttgc tataataaca gatggtaatc
     5521 ctctaattct tgaaggacct tgttgtgttg acccagatgc attagtagct tggactggaa
     5581 gagaaccata tcctaaagta tcaaaactat catggaagac ttttattggt cagacttcag
     5641 gagaatctta tcatatggaa tttgttgaac ctggacaaat agtcattata caaccatctg
     5701 aaagattgtc tggcttaaaa acagattcta caccttctga tagaatgagt tcaggtggat
     5761 taagacttgg catagattaa atcttatgat atagcttaat tattatttaa gatattaaaa
     5821 aataaaaagg gtagcaggga tagatatgtt aaaaggagtt ttatatgttt gagaaaattc
     5881 ataaaaggtt taaaggatat tatatttttt taataatttt aattttatgg aagatagtat
     5941 gtgttttggg tatatggagt agctatattc tgcctcctcc tgaaatagtc ttagatactt
     6001 ttataaaaat gatatatgac ggttctattt tcttaaatgt ttatgccagt gtaagaagga
     6061 tattaatagg ttttttaata agttcattga tggctatacc acttggagtt gtatttggag
     6121 taaataaaaa aatgtatgaa tatttcaaac cactatttga atttatgcga agtacacctc
     6181 cactagcttt ggtgccaatg cttattttat ggtttggtat aggtgaagaa tctaaaatta
     6241 taattattat tttggcatcc ttttttccaa tatttttaaa tacattgaaa ggtataaaaa
     6301 attgtgacaa taaattaata gaagtaggta aatcttttaa tttatctaaa aagagaattt
     6361 tttataaaat aataatccct aattctatgc tggatattgt tgttggactt agtttagggc
     6421 ttgggtatag ttttagggct ataattggag cagagcttat tgcagcttct tcaggactag
     6481 gatatttgat ttctgatgga aaagatatgt ctagaactga tgttgtattg gtaggaattt
     6541 ttgttattgg atttttaggt atactttcag attatctatt ttcaaagata ataacaaaat
     6601 ttagcaaagg gaagcaggtt gatttaaatg gttagaagtg gatttttgct agagaatata
     6661 tataagaaat atttagttga taataaagag catttagttc ttgataatat atctttaaat
     6721 atatctagtg aagagataac tgttatatta ggtgaaagtg gatgtgggaa aacaacgcta
     6781 cttagaattt tagcagggct tgaaaatgct actagtggaa acatatattt ttttaataat
     6841 gataaaaagt gtactccaaa agtaggaatg gtatttcaag aaagtagact tatgccatgg
     6901 ctgaatgtaa gtgaaaatat acttttacat actgaaaaag ataatagaaa taaagttgat
     6961 ttagacaagt atttaaaaat gatgaagctt gaaaagttta aaaactcata tccaaatgaa
     7021 ttatcaggag gaatggctca cagagtaagt atagcaagag cactttcctt caatcccgat
     7081 attttgctga tggacgaacc atttgcagcg ctagattact tcacaagaag aaaaatgcaa
     7141 aaagaagttg taaatatcca taaaaatact aaaaaaggtg tagtatttgt aactcacaat
     7201 attgaagaag ctatggaaat agcaaagaaa ataattgttt ttagtaaaaa taaaaggatt
     7261 aaacaattta gtgtcgaaga tgaatataat agagatttaa ctaaaaacta ttatataaac
     7321 ttgaaaaaag aaatattaag ggaattgggg gagttttaat tgattaaaag aaacaaaaag
     7381 attttagcag taatgacatc tttaataatg gtgttggttg ggactgtagg atgttcaaca
     7441 acaaatgata agaaagatga acctgcaaaa aaagaggcta gtttacctaa ggaaataaat
     7501 ttaacttatg taaaatcacc acttaatgtt cctagtatat tagaaaaaaa ggatgattta
     7561 tttggaaagg aatttaaaaa ggacaatata aaagtcaact tccatgaatt gacaacagga
     7621 ccagagcaaa ctcaagcatt agcagcaggt gagctagact ttttacatgc attaggagga
     7681 acgtctgcaa taatagctgc atcaaatggt gttggtctta aaattacgaa tatttatagc
     7741 cgttcaccaa aaggatatat gcttataact aataatgata atattaaatc tataaaagac
     7801 ttaaaaggta aaaaaattgt aggtccaaaa gggactatac ttcatcaact gttgattgct
     7861 gcacttgcta aagaaggcta tactatagat gatgttgaat atgtaaatat ggatattcct
     7921 agtgctgctt ctgcattaga aagtaaaagt gctgatgtag caatgcttgc aggtccagtg
     7981 gcattgaaaa cgataaattc aggtgccaaa atgattgtaa atggagaagg attagtaagt
     8041 ggaataatag ttactgctgt aagtgatgac tttgctgaaa aatatcctga attagtaaaa
     8101 agatttatga aggttcatga agaaacttta aaatatatga atgaaaacaa ggatgaagtg
     8161 atggatgttg tatctaaaga agttggttta tctttagatg aaacaaaaga aatgtattct
     8221 tggtatgact ttagttctaa aataacggac aaggatataa aagaattaga agatacacag
     8281 gaatttttga tgtctaatgg aatgcaacaa aagaaaataa atattaaaga tatgttgtac
     8341 aatcaaaatt agaatacttt aaaatattaa agtggaaaat acacccttat ttattatgga
     8401 aactgtatgg taaaagaggg tgtattttta ttattataca aaaatacaat taaaaacaac
     8461 ttactatttt atctacactt atgtagtcta gtaattttct cattttctta cggtgaagta
     8521 aaaactttga atatgtgtcc tcggattgtt ttgtgtcacc ataaactttc caatatttaa
     8581 tcatagaaac ttcataatta ctatatccca taaatccaat cacatcttta agaggatatc
     8641 ctaaaaaaat acctatttca tcaggaaaaa catcactctt aagtttattt actaaatgct
     8701 ctaaataagc attaacattc gtattttgtt tgtatcctaa aaactttaaa aagtttactg
     8761 tttttttaca ttttaatttt tctgataatg cttttttatt tacaaataag atttttaatc
     8821 cctttttttc tttatcaata actataaaat ctattttctt acatttatat agatatttat
     8881 aaatatcatt aattttttcc tctctattta catcagtaaa cgaaatattt attatttcag
     8941 caggtttaga gcctaaaaag actggaccta aaacctctaa aagccatttt atatatgatg
     9001 attcaatttt atttttacaa caaaattgtg aattacaaca agacataaaa gataacctcc
     9061 ttcaaatgaa aattaatatc aagtaattag attatactat gaatgataat caatat
//
LOCUS       DAMJWO010000112         9026 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.116, whole genome shotgun sequence.
ACCESSION   DAMJWO010000112 DAMJWO010000000
VERSION     DAMJWO010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9026
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.116"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(355..1251)
                     /locus_tag="PC366_003325"
     CDS             complement(355..1251)
                     /locus_tag="PC366_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2578809.1"
                     /translation="MKDKNTYFNRKGQENFIDIFLKDDIKKGANFKRHWHEHLQIYYF
                     IDGIAYLECGLDNFKVVPGNIVIANSNELHYLESLSDNLKFYSIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDFLILKCITTILDEYHNKEVGYELSIKANIYQLIVL
                     LLRSHIDKIYSEDEFIKRKYSLEKFECIFDLIEEKYMDKITLKELASRVNLSAHHFCR
                     TFKQITGKTTIDFINGIRLDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKRNYNI
                     SPTKYRNEHREVSNVILKEDMK"
     gene            1393..2820
                     /locus_tag="PC366_003326"
     CDS             1393..2820
                     /locus_tag="PC366_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2578810.1"
                     /translation="MTNSFKKDDNRKKITVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLASIEWVIASYSIIICSTLLFFGRLGDIIGKSRVFQVGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKESRGKALGILVTAVAIGNMVGPSVGG
                     FILSIFDWNVIFFINIPIGLIVIFLNTKFLPNSKKSSENMDKTGAILQFLGTTLFFSA
                     LISAQQTGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRNFKFSLNLICAL
                     TSFICIASSSILIPFYLQSTMKLPPIQAGLFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLVMSFGFFLMSRLKESSALILFVIYISIISIGQAIFQPANNALIMSSCSRSKL
                     GVVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYVINNDKIFVFGMRNVYI
                     IVTLVCLIGAILIGFYLFKYNKNEQ"
     gene            complement(3017..5611)
                     /gene="clpB"
                     /locus_tag="PC366_003327"
     CDS             complement(3017..5611)
                     /gene="clpB"
                     /locus_tag="PC366_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HDF2578811.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNDFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSDDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(5648..6244)
                     /locus_tag="PC366_003328"
     CDS             complement(5648..6244)
                     /locus_tag="PC366_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578812.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIAKSKEVFDF
                     FNSDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            complement(6261..6665)
                     /locus_tag="PC366_003329"
     CDS             complement(6261..6665)
                     /locus_tag="PC366_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HDF2578813.1"
                     /translation="MDKTLKKDLNQEYTESKSLVMNKSKYMNICFKNYIKVVEGMYTK
                     RDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIAYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            7032..7406
                     /locus_tag="PC366_003330"
     CDS             7032..7406
                     /locus_tag="PC366_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDF2578814.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            7403..8266
                     /locus_tag="PC366_003331"
     CDS             7403..8266
                     /locus_tag="PC366_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578815.1"
                     /translation="MISMDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGK
                     TTTLKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIM
                     SKIYKNWNDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHKPKLLILDEATS
                     SLDPIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDE
                     LIDTMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRNPNCIVDNTSIE
                     EIMLFYVRGDK"
     gene            8266..8904
                     /locus_tag="PC366_003332"
     CDS             8266..8904
                     /locus_tag="PC366_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDF2578816.1"
                     /translation="MKGLILKDLLNLKGNVKFILLFIIMFGFMSSLGDGNVNNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGTERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
BASE COUNT         3019 a         1323 c         1041 g         3643 t
ORIGIN      
        1 tttcttttaa ttctttagga tggatttaaa ttttctataa aaatcatact attttagctg
       61 tttacttgct tatttgatag ttttatttct ttgattaaat atctttcaga atctaagcca
      121 gatgtctcaa aaaaactgat ttataatata atcatttttt ctgctattct tatttttcca
      181 attttagttt catattaaaa tatacttttc atagacacta cattctttca tactcatttt
      241 cacatttaac tatacaagta gtcttactca tttatgtact atactttatt aatatttatt
      301 aagaaaaact caaagattta aaaatatata ttttctataa agtatattta tgaattattt
      361 catatcttct tttaaaataa cattactaac ttctctatgt tcatttctat acttagttgg
      421 agatatatta taattccttt taaataagcg actaaaataa tttatgctat caaagccaca
      481 tctcatagca atttctgtca tatttaaatc tgtttccttt aaataatata tagctttatc
      541 aagcctgatt ccatttataa aatcgattgt agtcttacct gttatttgct taaatgttct
      601 acaaaagtga tgtgcactca agttcacacg actagcaagt tcttttaatg taattttatc
      661 catatatttt tcttctatca agtcaaagat acattcaaat ttttctaaag aatactttct
      721 ttttataaat tcatcttcag aatatatttt atcaatatga cttcttaata agagtactat
      781 taattgatag atattagctt ttatagataa ctcatatcca acttctttat tgtgatattc
      841 atcaagtata gttgtaatac attttaaaat cagaaaatca ttttgaatta aattattaaa
      901 tacaatatga tttaaagcca atggtgctaa gtacttagtt tgtaacaaat caacttgatt
      961 actaaaaagg aatgtgggct caatacgaat actatagaat tttaaattat ctgataagct
     1021 ttctaaataa tgtaattcat tactgtttgc tattacaata tttccaggca ctaccttaaa
     1081 attatccaat ccacattcaa gatatgctat accatcaata aaataatata tttgtagatg
     1141 ctcatgccaa tgtcttttaa agtttgctcc ttttttaatg tcatccttta aaaaaatatc
     1201 tataaagttt tcttgacctt tcctattaaa atatgtattt ttatccttca ttattccccc
     1261 ctcatcaaaa tagtgctaat tataagcaat atagttattg tattcattat ttcatatcgc
     1321 tattatataa aatgtaacta tcattgtaaa cattaacata atgccagtca ttataataag
     1381 gaggtaataa aaatgacaaa ctcttttaaa aaagatgata atagaaaaaa aatcacagtt
     1441 ttatttgtag tcattgccat gacttttatg gcaacattag attcgagtat tataaatgtt
     1501 gctctcccag ttcttgcaag caaactaaat gtatctctag catctattga atgggtaata
     1561 gcaagttact caattattat ttgttcaaca ctattatttt ttggaagact tggagatatt
     1621 attggtaaat caagagtatt ccaagtaggt actattctct ttacatcagc ttcattacta
     1681 tgtggattaa gtaattcttt aactttactt atagtttgcc gctttattca aggaataggc
     1741 gcttctgcct acatggcaaa caatcatgga attatcacag aactatttcc aaaagaaagc
     1801 agaggaaaag ccctagggat tctagttact gcagttgcta ttggaaatat ggttggacca
     1861 tctgtgggag gatttatttt gtcaatattt gattggaatg ttatattttt tataaatatt
     1921 ccaatcggtc ttattgtaat ctttttaaat acaaaatttc ttcctaatag taaaaaatct
     1981 tcagaaaata tggataaaac tggtgctata cttcaatttt taggaacaac attatttttt
     2041 agtgctctaa ttagtgctca acaaacagga ttactaaatc catatatatt aattgcacta
     2101 ttattatcaa ttatttttat tatattattt ttgatattag aaaaaaaaca tcctcaaccg
     2161 cttcttgatc ttgaaatttt tagaaatttt aaattttcat tgaatttaat ttgtgctctt
     2221 acatcattca tttgtattgc atcatcaagt attttaattc cattttactt acaaagtact
     2281 atgaaacttc cccctattca agcaggttta tttatgatac tatcaccttt gattttagcc
     2341 attttttcac ctatatttgg gaatatatca gataaaatca agtcagaaaa aattatttta
     2401 attggtcttc tcgttatgag ttttggattc tttctaatgt caagattgaa agaaagttct
     2461 gcccttattt tatttgtaat ttatatatcg ataatatcaa taggacaagc tatatttcaa
     2521 cctgctaaca atgctttgat aatgtcaagc tgttctagaa gtaagctagg agttgtagga
     2581 agcataaatt cccttgtaag aaatttagga caagttatag gtattactat ttctacaaca
     2641 cttttatata attttatgag tattaaagct ggatataggg tcaatgatta tgtgattaat
     2701 aatgataaaa tatttgtatt tggaatgaga aatgtttata ttattgttac acttgtttgc
     2761 ttaataggtg caatattaat tggcttttat ttatttaaat ataataaaaa tgaacagtag
     2821 ttttttataa ttatattcaa attatgatta tattataaga aacttactaa aatacttcct
     2881 ttgagttaaa tttaatttgg acatattgac ttaaaaatgt tttattaatt tgataaaata
     2941 tttcttttcc tatagtttat aaataaaaat cagctgagca aaatatttag tatattatgc
     3001 tcaactgatt cttttattat ttaactaaaa cttcaatatt ttcatctttt ccatctataa
     3061 ctatagtaca tccattatac acatctccag caataagttt ctttgcaatt atagtttcta
     3121 atgtatttcc tatatatctc ttaagaggtc ttgctccata tacagggtca tatccttctc
     3181 tcaccataac atcttttgct gaatttgtaa cttcaatagt aatatctttt tcttttaatc
     3241 tattttttaa atctttcata aatatatcta taattttctt gatattttct tggtctaaag
     3301 gcttaaacat tataatatca tctactctgt ttaaaaactc aggtttaaat ctatgcttca
     3361 tttcattcat tactaaattg ttagtagtct ctgttatatt tcctcctgct tctaatagat
     3421 aattacttcc tatattagaa gtcattatta taagagtatt tttaaagtct actgtcttac
     3481 ctttattatc agtaagtcta ccatcatcta atatctgtaa gaacatgtta aatacatcct
     3541 catgtgcttt ttctatctca tcaaatagta ttacagaata aggagcacgt ctaactgctt
     3601 ctgtaagttg accaccctct tcatatccca cgtaccctgg aggaggtcca actagtcttg
     3661 atacagcatg tttttccatg tattcagaca tatctattct tattatatta tcgtcactat
     3721 cgaataaatt tctagcaaga gtttttgcaa gttcagtttt accaacacct gtagggccta
     3781 agaaaataaa tgaaccaatt ggttttcttt catcttttaa tcctgctctt gcacgtatta
     3841 ctgcatttga aactgctgta actgcttcat cttgtccaat aactctttta tgaagttcat
     3901 cttctagttt aagtaatttt tctctttctc cttcaactag tttagttact ggtatacctg
     3961 tccactttga tacaatgcta gatatttctt cttcagtaac ttcttctttt aaaagagaat
     4021 tttcagaacc atcattcata ttttcttcgt actgctttat ttgttcttct aacttaggta
     4081 tttcaccata tttaacctct gctgctttgt tgaaatcata ttctctttca tacttttcag
     4141 ctttaccttt agcttcgtct aattgagcct ttaagttttt aatatctaat atttgactct
     4201 tttctttttc atattttgct gtcatttcat catttttaga ttttaactct gctatttctt
     4261 tttgaatatc atccaatctt gatttgcttt tatcatcatt ttctttaagt aatgcttctc
     4321 tttcagtttc taatgtaaat aactttcttc taacaacatc taattctgtt ggcaatgaat
     4381 ctatttcact acgaatcata gctccagctt catcaattaa atcaattgct ttatctggta
     4441 aaaatctatc ttgtatatat ctatgagaaa gttttgctgc tgctacaata gcattatcat
     4501 gtattcttac tccatgatgt atctcaaatc tttcttttaa acctctaagt atagatattg
     4561 tgtcttcaac agtaggttct tctgcaatta caggctgaaa acgtctttca agagccttat
     4621 ctttttctat atactttcta tattcatcaa aagtagttgc accaatacag ttcaattcac
     4681 ctcttgcaag cataggttta ataagattac ctgcatccat tgaaccttct gttttaccag
     4741 ctccaacgat agtatgaatc tcatctataa acagtataat ctttccatca gaactttgaa
     4801 cttcttttaa aactgccttt aatctttctt caaattcacc tctatatttt gcaccagcaa
     4861 ttaaagctcc catatcaagt gagaatacaa tcttatcttt taaaccttct gggacatctc
     4921 ctcttactat tctctctgct aacccttcta caattgcagt tttacctaca cctggctcac
     4981 caatcaatac aggattattt tttgttcttc ttgataaaat tcttataatc cttcttattt
     5041 cttcatctct cccaattaca gggtctaatt tatttttctt ggctaaatct actaagtttg
     5101 ttccatatct agcaagtgca tcatatgtgc cttctgggtc ttgtgtttct actctttgac
     5161 tacctctcac ttgtgataaa atatttaaaa agtcattctt atttatatta tattgtttta
     5221 atattttacc aacagctgat tttgattctg tttccatcat tgcaagcata acatgctcta
     5281 cacttatata tgaatcttta aattctttag aaatactctc tgcctttata agcacctcat
     5341 ttatttttct agtagctgat actccttgtg agtcagcacc ttctccatat acttttggaa
     5401 gcttatcaat ttcaaagttt acagtatttc tcaaagaatc aattgatata ttcatttttt
     5461 cgattatatt tggtatcaat ccatcctctt gattaataag tgctgagaaa agatgaatta
     5521 catctacttg ttggttatga ttttttactg cttcgttata agcctcattt aaactttttt
     5581 gaactcttaa agtcattttt tctacgtcca tataaatccc tccattttaa tattatatcc
     5641 aaataaatta aattctctca tttataatta ttgattttct aagctctaaa agactatcaa
     5701 gtaaattctc gtttttttgt atatcgaaac tcaatgttaa attaaatgtt ccatctgaat
     5761 taaaaaaatc gaatacttct tttgattttg ctattaaata caagtcttca tctataagtc
     5821 ttttttcacc tattaataaa tactgacatt tatctataaa actcttttta aaatcaatag
     5881 tgtatagatt ttctaaaata ttatattgat aaatagcaat attattaaac acttttaata
     5941 tgtttgaatt tacaaaattg taaatttgat tattgttata cagtgatatt tgttcgtata
     6001 tatattccct aaataaagga tgaatgtttt gcttaagttt taaagtaact tcagctggta
     6061 tttcaaaata aagcttccag tacttagagt tatttttttc taaaataaaa gctactttgt
     6121 tcaaactggt agaactaatc tcctttagtg tacaattaaa attatagtgt ctcaaactag
     6181 ttttttcatt ctcaaataca tagtcaaacc actgtagaac atttctatca agttttaaac
     6241 tcatataaaa accttcttcc ttatttacta accttattag gtctttttat ctgattatat
     6301 tctgctaata aactttcttt atcagctcta ctacctttat atgctatatg tggatttatc
     6361 atatactcac catttttcac tctttgtaaa aaatccattt ttttcaactc cgtaaacaat
     6421 gaagataaag aagtttttgg atattcaaat tcacaagata attcatataa tgtttttcta
     6481 atcttattat ttttatccat agagtttatt aattttaatg gaattaaatc cctcttagta
     6541 tacattcctt ctactacttt aatataattc ttaaaacaaa tattcatata cttactttta
     6601 ttcataacta aacttttgct ctctgtatat tcctgattta aatccttttt taatgtctta
     6661 tccaaattaa atatctcttc tcactctcct tatctctaat tgataatata aatatattac
     6721 aaaaaaatat gtatgtcaaa actgaaaatg caaaaagttt accttataag taaacttttg
     6781 tttagctata agctaaactt tattattttt ttaatttagt atttccaatt tattggcagg
     6841 atttttgaat aatatttata aattttttaa aaaaatttaa atctatttaa tatggcagcc
     6901 tttcataaaa tacattacat ttattaaatg tataatattg gtaattagtt ttttctaaaa
     6961 tcagttgaca tattatatat atatttatat aatgtgtata tactatatat acaatttaag
     7021 gaggtgactt attgaatata gttattagta attcgagtgg gaagccaata tatgaacaga
     7081 ttactacaca aattaaaagt atgattataa gcggagagtt accagaaggc tcagctcttc
     7141 caagtatgag actattggca aaggaactta gaataagtgt aattactaca aaacgagcat
     7201 atagcgattt agaacgagac ggatttattg agacagttac tggtaaaggc agttttgtat
     7261 ctagtaaaaa catggatttt gtcaaagaag aacaatttcg tttaattgaa gaatacctac
     7321 aaaaagcagt tgatacagca aaaagtagtg atattacata tgacgaatta aaagatattt
     7381 tatttttatt atataaagga gaatgataag tatggatgca ataactataa aaaatttaaa
     7441 taaaacttat aaagatttta gcctacaaga tatatctttt tcagtaccaa aagggagtgt
     7501 aatgggattt gtaggtgaaa atggtgcagg aaaaacaact acattaaaag caattttaaa
     7561 tttaatatct tatgatagtg gaaatataga aatatttggt cttgatagta aaaaaaatga
     7621 aaaagaaatt aaagagcaaa ttggggttgt atttgaggga agcaactttc atgaaaattt
     7681 aaacactgac catgtttcaa aaatcatgag taaaatctat aaaaattgga atgacacatt
     7741 atttaaagac tacttaaaaa aattgagagt accagacaat aaattaatta aggagttttc
     7801 aaaggggaat aagatgaaac ttagtattgc tgtagcctta tctcataaac caaaattatt
     7861 aatactagat gaggcaacta gttcacttga ccctatcgtt cgtgaagaaa tactagatat
     7921 atttttagat tttatacaag atgaagaaca ctctattatc ttatcttcac atattacaag
     7981 tgatttagat aagatagcag actatattac atttatacat aaaggaaaaa ttgtatttag
     8041 tgaaaataag gatgaattaa ttgatactat gggagtttta aaatgtaaac ctagtgattt
     8101 tgataacctt tcaagagagg attattcata ttatcgtaaa agccaatttg gatatgaagt
     8161 acttcttaaa gataaacata gatttatatc aagaaatcca aattgtattg ttgataatac
     8221 gtctatagaa gaaattatgt tattttatgt gagaggtgat aaataatgaa aggtttaatt
     8281 ttaaaagatt tacttaattt gaaaggaaat gtaaagttta tacttttatt catcattatg
     8341 tttgggttta tgtcttcttt aggagatgga aatgttaata actttatagg tgttattata
     8401 gttttatgta ctacaatgat tgtttcaaca ttttcatatg atgatttaaa taaatgggat
     8461 agttatgtac ttacaatgcc tattaatcgc aatgatattg tattaagtaa atatttaact
     8521 atgttaatat ttagctttat aggtgttctt gtttcactta ttgttagtgt aactattggt
     8581 tattttaaaa atacacttat attaaatgaa acactactta ttaatgcact aatcttatca
     8641 atttcagtat gttttggtag ccttattcta ccacttattt ataaatttgg tacagaaaga
     8701 gctcgtttat taatgatttt atgcttttta gttccaacac tagctttatt agtttttaaa
     8761 agtattttag aaaatattag ttcacctatt tctatagaaa ttatacttaa tacactagta
     8821 tattctcttc catttgttgc tattttacta tttgtgattt catattttat atcatcaaaa
     8881 atctatagta aaaaagaagt ataaaatata ctatacatgt ctctgtattt aagtatttta
     8941 aataaaatac tatcaagttt attttggtag tattttattt ttttattatt aatatctact
     9001 aggtatttat tgttttatta cttata
//
LOCUS       DAMJWO010000113         8915 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.117, whole genome shotgun sequence.
ACCESSION   DAMJWO010000113 DAMJWO010000000
VERSION     DAMJWO010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8915
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.117"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            92..658
                     /locus_tag="PC366_003333"
     CDS             92..658
                     /locus_tag="PC366_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HDF2578817.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
     gene            963..1424
                     /locus_tag="PC366_003334"
     CDS             963..1424
                     /locus_tag="PC366_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2578818.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNKVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEDEKYF"
     gene            1492..3738
                     /locus_tag="PC366_003335"
     CDS             1492..3738
                     /locus_tag="PC366_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011009877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578819.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELNKITLFMDKSSKDKVLDNYTLLNKKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNVIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFESMPESMITQSSVSYVRSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMISMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEAQEFKEDKKGLVEFKNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKDATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            3731..5563
                     /locus_tag="PC366_003336"
     CDS             3731..5563
                     /locus_tag="PC366_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578820.1"
                     /translation="MSRMGRGPMGKSMEAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILTFLLFLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISAKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAVLILPISMFVISRIIKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEVQIVENAVSIDGLEGKIDFENVNFGYNPNKTIINDFSVNVK
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYKMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            6282..7559
                     /gene="hflX"
                     /locus_tag="PC366_003337"
     CDS             6282..7559
                     /gene="hflX"
                     /locus_tag="PC366_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDF2578821.1"
                     /translation="MDMTKKGITVGLNINNKSEDFNELMIELENLCSACDIDVVGSIT
                     QNAKQVNRAFYIGTGKVEEILNLIKKENIEIVIFYNELSTSQLKNLEEKLNCEIIDRT
                     ALILDIFAQRAKTREAKLQVEVASLKYMLPRLIGSNENLGRQSGGVGTKNRGSGEKKL
                     ELDRRRIEEKITSLNRELYDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLV
                     DIFKNSEEKKVFEKNMLFATLETSVRNIVLANNKEFLLSDTVGFVSNLPHDLVKAFRS
                     TLEEACEADVLLHVIDISNPSYKSHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVEVL
                     DRILDSIDKEGIFVSVKKDINIDKMIKCICDSIFKDCVRCKFLIPYDKGHVVSYFNEN
                     TSIINTEYREDGAILDVECSNIEYNKYKKYALE"
     gene            7792..8289
                     /locus_tag="PC366_003338"
     CDS             7792..8289
                     /locus_tag="PC366_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDF2578822.1"
                     /translation="MDAESLMKKYMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIQIEQNEKDSRAI
                     CLVTKDRVQEYSKKVRGMQEKVLQLLFEDFTEKEVEQLFFGIMKLSIGIENVKNYVEN
                     NDVGE"
     gene            8339..8863
                     /locus_tag="PC366_003339"
     CDS             8339..8863
                     /locus_tag="PC366_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF2578823.1"
                     /translation="MKSVVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFLKKNYKDLQKKNLVVFGVGAAPYDDEVIKKLREVNFKDE
                     LNKVPCFYCRGAWDETKMSFIDYTLCSFFKKSIAKKERQGLKPAEAPLLSGEAFDWCN
                     KENLTPILNYIRKL"
BASE COUNT         3532 a          898 c         1616 g         2869 t
ORIGIN      
        1 ttaataaata taaattaaat tatatgtgta tatattgtac tttaatagtg atataataat
       61 aaaaaaattt ttaaagaggg tgatattaca tatgagaaaa cttgaagaga tattagaata
      121 taataaatca tttgtagaga acaaagaata tgaacaatat gtgacatcaa aacatccaaa
      181 taaaaaaata gtagtcttat cttgtatgga tacaagatta actgagcttt tgcctaaggc
      241 tatgaatttg aaaaatggag atgtgaaact aataaaaaat gcaggagcta ctataatgca
      301 tccttttgga agtattatga gaagtgtttt agttgcaatt tacgaatttg atgtagatga
      361 ggttatggtt gtagggcatc atggatgtgg tatgtgtaat gttgatacag ataagttact
      421 tggtaaaatt ttagatagag gaatatctaa tgatgtaata cttacacttc gtagtgctgg
      481 aattgataca aaacaatggt tacatggatt cgattctgca gaagaatctg taaaagatag
      541 tattgattta ataaaagggc atcctttaat tccagatggt attattgtac atggtctaat
      601 tatatcacct gaaactggga agttagacgt tgttgtaaat ggatatgaag ataagtagag
      661 tattgtaatg ttatataatc aagatactgt tgaatatgat gttgtttcaa aatttatttt
      721 gggacaactt ttttatttga aaatatatga aaaggtttat tttaagcttt acaataaaaa
      781 atataagtag ctgactaatt aaaaatctta ctattattta ttaaaattat aactatatga
      841 tataaaaata tttaataaat gaaatttata tgaatttttt ataaatatat tgaaaaaatg
      901 catgcagtat agtaaaataa tgcttagccg actaagtaat ataaaaaata aggagggcaa
      961 gtatgaatag caattctgaa gaaaaattaa atgatgtttt cttgcaatta atgcgaatat
     1021 attttataag aactcatttt tattttgata aattaggctt atatcatggt caaccccaaa
     1081 tacttttttc tttaaagatg aaagatgggc aaagtcaaaa agaattagca gataaaagga
     1141 aagtaaaagc atctacaact acagttatga taaagaggat ggaaaaagct ggacttgtgg
     1201 aaagaaaaca agatgaaaag gaccaaagag tatctaggat ttttttgaca gacaaaggtt
     1261 tagaaatatg taataaagtt gaagaattta acaaggaatt ggaaagagag ttttttttag
     1321 gatttagtga agaagaaaaa atagtactta gaagacttct aatgcaagta cgagataatt
     1381 taaaagcagg atgtcataag catgaagatg aaaaatattt ttaaagttta aaataatgtt
     1441 tttcaattta atgttattag actaattaat attacagaag ggaagaaatg tatgtttaaa
     1501 ttaattaaat atttaaagaa atcggcatta tcaatagtaa taatagtctg tctattggta
     1561 attcaagcgg tatgtgacct ttctttacca gaatacacat ccaatatagt aaatgtaggt
     1621 atacaacaag gtggagtaga aaactctgtt ccatctgtga ttagagagag tgaattaaat
     1681 aaaattactt tatttatgga taaaagtagt aaggataaag tactagataa ttatactttg
     1741 ctgaataaaa aggattatgt taagtataaa gataagtacc caggtctaaa agatgaatct
     1801 ctttatgagt taaatactaa agacaaagac actatagatg atttaaatgt tatttttggt
     1861 aaagctattt taatagtatc agggcttgag ggcgatagta aagaggtaaa agctatgaaa
     1921 gctcagttaa tgagtaaact tccaccacaa gctactcaaa gtggagatgt tgatatattt
     1981 aaattgttat cagcaatgcc aaaggaacag ttagatacat tgactaaaga gatgagcaaa
     2041 ggctttgaaa gtatgccaga gagtatgata acacaaagct ctgtttcata tgtaaggtca
     2101 gaatatgaga aaataggtat tgatacagaa aaaactcaaa ataattatat attatttact
     2161 ggtgctaaaa tgcttggtat agcaatgatt agtatggtag ctacaataac agtaggattt
     2221 ttagcagcaa gagtagcagc aagtgtaggt agaaatttaa gaagtggagt atttagaaaa
     2281 gttatgtcat tttcaaatac tgaaatgaat gaattttcta cagcttcatt aattactcgt
     2341 agtacaaatg atattcaaca gatacaaatg ttgatggtta tgttgcttag aatagtattc
     2401 tatgcaccta taatggctat aggtggagtg ataaaggttt taaacacaaa tacttcaatg
     2461 gcctggatta tagcagtagc agtagttgct atcttatcat taattgtagt gttattctca
     2521 gtggttatgc ctaagtttaa actggttcaa aagcttgttg ataagttaaa cttagtaagc
     2581 cgtgaaataa ttactggtat tccagttatc agagctttta gtactgaaaa acatgaagaa
     2641 gaaagatttg ataaagcaaa taaaaattta actaaaacaa atctttttgt aaatagagtt
     2701 atgacatgta tgatgcctgc tatgatgctt ataatgaacc ttatcacagt tcttatagtt
     2761 tggagaggtg catacagtgt tgattctgga gcaatgcaag ttggagatat gatggcattt
     2821 atacaatata caatgcaaat aataatgtca ttcttaatga tatcaatggt atctattatg
     2881 cttccaagag catccgtttc agctacacgt atagatgaag tattagtgtc agatataagc
     2941 ataaaagacc cagaaaaatc agaggcacaa gagtttaagg aagataaaaa gggtcttgtt
     3001 gaatttaaaa atgtttcgtt catgtatcca gacgcagaag aacctatatt aacaaatata
     3061 tcttttacag caaagccagg agaaacaact gcctttatag gaagtactgg tagtggtaag
     3121 tcaactctta taaatttaat tcctcgtttc tttgatgtta ctgaaggaga aatattactt
     3181 ggtggagtta atataaaaaa tgtttctcaa catgatttaa gggaaaaaat tggatatgta
     3241 cctcaaaagg gagtattgtt ttctggtact atagaatcca acttaaaata tggtagaaaa
     3301 gacgcaacag atgaagaaat gagaacagca gctgaaatag ctcaagctac agaatttata
     3361 gattctaaac cagaagcttt taaaactgaa atttctcaag gtggaacaaa tgtatctgga
     3421 ggtcaaaaac aaagactttc tattgcaaga gcaatagcaa aaaatccaga agtttatata
     3481 tttgatgata gtttttcagc acttgactta aaaactgatg cagctcttcg taaggcttta
     3541 aaatcaaaaa ctgctgaaag tacagttcta atagttgcac aaagaattag tactatctta
     3601 aatgcagaac agataattgt tttaaatgag ggagaaatag ttggaatagg aacacataaa
     3661 gagcttctaa aaaattgcga agtttatgag caaatagctt tatcacaact ttcaaaggag
     3721 gagctagcta atgagtagaa tgggaagagg tcctatggga aaatctatgg aagcaggaca
     3781 aaaagcaaat gactttaaag ggactatgcg aaaactaatt gcatatttat ctaaatttaa
     3841 aatatcaata attttagtaa ttgtatttgc tattggtagt gcatcgtttt ctatagtagg
     3901 tccaaaaatt ttaggaaagg caactacaaa gatatttgaa gggttagtga gtaaagtttc
     3961 tggaggaaac gtaggtatag attttaatgc aattggaaaa atcttaacct ttttactttt
     4021 cctttatttg ataagtgcac tgttctcttt tatacaagga tttataatga gtggaatttc
     4081 tcaaaaagta tcctataatt taagaaaaga gatttcagca aaattggata gattaccaat
     4141 gaagtatttt gatactaaga cgcatggtga aatattatcg agaattacga atgatataga
     4201 tactttaaat caaagtttaa atcaaagtat gacacagctt ataacatcag taacaactat
     4261 gataggtgtt ttgataatga tgttatctat aagtggaatt atgacattag tggcagtttt
     4321 aatattacca atatcaatgt ttgtaatttc aagaataata aagaaatcac aaaaatactt
     4381 tagatatcaa caagaatatt taggaaatgt aaatggtcaa gttgaggaaa cttatagtgg
     4441 ccaaacaata gtgaaagcat ttaatcgtga agatgaagta attgaagagt ttgataaact
     4501 aaatgatagc ctgtataatt cagcgtggaa atctcaattt ttatcaggta taatgcaacc
     4561 acttatgatg tttattggaa acttgggata tgtaatggta tcaatcttag gaggttggct
     4621 tgcaattaag aaaacaattg aggttggtga catacagtca tttatacaat atgtaagaaa
     4681 ctttacacag ccaatgactc agattgcaca ggttgccaat ttattgcaat caacagcagc
     4741 agcttctgaa agagtatttg agtttttaga agaggaagaa gaagtccaaa ttgttgaaaa
     4801 tgcagtttca atagatggtt tagaaggtaa aattgatttt gaaaatgtca actttggata
     4861 taacccaaac aagactataa taaatgattt ctcagtaaat gttaaacctg gtcaaaaagt
     4921 tgctattgtt ggacctacag gagcaggtaa aactacaata gttaaactgt taatgagatt
     4981 ttatgatgtt aatagcggtt caatactgat tgatggtcat aatattaaag attttaatcg
     5041 tagtgagctt agagaaatgt ttggtatggt tcttcaagat acatggttat ttagtggttc
     5101 aattatggaa aatataagat atggtaagtt gaatgctaca gatgaagaag ttatagaggc
     5161 tgctaaatct gcacatgttc atagatttat taagacgtta ccagatggat ataagatgaa
     5221 attaaatgaa gaagcaagta atgtttctca aggtcaaaaa caattattga ctatagctcg
     5281 tgctatttta gctgatccta aaattttaat attagatgaa gctacaagtt ctgtcgatac
     5341 tagaacagaa gtattgattc aaaaagctat ggataatctt atggaaggta gaacaagttt
     5401 tgttatagcc cacagattat caactatacg tgatgctgat atgattcttg taatgaatga
     5461 aggagatata gttgaacaag gaaatcatga ggaacttcta aagaaaggcg gattctatgc
     5521 caatctttac aattctcaat ttgaagaaga tgaagcaatg taacaaaaaa ctatcttagc
     5581 atagacatgt aattaataag ataaaataaa tgagggtgcc ttaaaatgaa ctttttaatt
     5641 cataaggcac tcttttgtgt atgaaataaa gtgtattttt atcattttaa caatgaaaaa
     5701 gaggattatc tatattttga gatagccaca taattttatg tctttacaaa gtgtttattt
     5761 tattataata tgtagtaagg aaaatgttgg aggtgattat caaaatgtat atttaatttt
     5821 attctttaaa ttttattata aatagaattt aattttaata gttgatgatt atattgaagt
     5881 atatgttttt attactttta ttaatcatgc aaataactac ttaaatttaa gaatagggtt
     5941 aaatataaaa tgataattac atataagtta attaaactaa tgtattttta atatatattt
     6001 agaattttaa tccttcttat gatataagta gcttgttttg tattacttag atttgtaagg
     6061 agttttttta ttgaaaaaac tgcataatat atttgggagg aggtgtaaga aagtgatttt
     6121 ttatataaga ttgagaaaat aatgcacgat tatggttatt ataatagtaa ataagaagtg
     6181 tcatttaagg ataagataaa aagcaaaatt cttgatgaat ttaattatag agccataatc
     6241 tcgtgctata gattaaataa aaaatagcag ataaggagaa tatggatatg acgaaaaaag
     6301 gaataacagt aggattaaac ataaataata aatctgagga ctttaatgaa ctaatgattg
     6361 aacttgaaaa cttatgttca gcatgtgata ttgatgttgt agggagtata actcaaaatg
     6421 caaagcaggt taatagagca ttttacattg ggacaggtaa agttgaggaa atattaaact
     6481 taataaagaa agaaaacata gagatagtta tattttacaa tgaactttct acatcacaac
     6541 taaaaaatct tgaagaaaag cttaattgtg aaattataga tagaacggca ttgatacttg
     6601 atatatttgc acaaagggca aaaactagag aagctaaact tcaagtagaa gtagcaagtt
     6661 taaaatatat gttaccaaga cttataggtt caaatgaaaa tttaggacgt caaagtggtg
     6721 gagttggtac taaaaataga ggttctggtg agaaaaaatt agaacttgac cgtagaagaa
     6781 tagaagaaaa gataacatct ttaaataggg agttgtatga tttaaaattc caaagagaaa
     6841 ctcaaagaag tatgagaaga aaatcaaatc ttccaaatgt agctctagtc gggtatacaa
     6901 atgctggtaa atcttcaata atgaataaac tagtagatat atttaaaaac tctgaagaaa
     6961 agaaagtgtt tgagaaaaac atgttatttg ctacacttga aacttctgtc agaaatatag
     7021 ttcttgcaaa taacaaagaa tttttattat ctgatactgt tggttttgta agtaatctac
     7081 cacatgactt agtaaaagca tttaggtcaa cattagaaga agcatgtgag gcagacgtac
     7141 tgttacatgt tattgatatt tcaaatccaa gctataaaag tcatattaaa gtgacagaag
     7201 atactttaaa acaaataggt gcagatggta tacctatgat acatgtgtat aataaaattg
     7261 atttaataga tgtagaagta ttggatagaa ttttagatag tatcgataaa gaaggtatat
     7321 ttgtttcagt taaaaaagat ataaatatag ataaaatgat aaaatgtatt tgtgatagca
     7381 tatttaaaga ttgtgtaaga tgtaagttct taattccata tgataaaggt catgtagttt
     7441 cttattttaa cgaaaatacg agcattataa atacagaata cagagaagat ggagctattt
     7501 tagatgtaga atgtagcaat atagaatata ataagtataa aaagtatgct ttagagtaaa
     7561 ttttgaaaaa cttattatag cctaaaatat atttaattta taatttatta taaattgatt
     7621 gtaaatatga ttttatgaaa cggtatagcc ataatgctat gccgttttgc catttataat
     7681 aaaaataaat ttattgacac aatagtaact aattactata atataaagta actagttact
     7741 atttaaaatt atcaaaaaat taaaatctaa gataaagaga agtgtataat aatggatgca
     7801 gaaagtttaa tgaaaaaata tatggtagat gatgatagta gaaaacaagc tatatttgca
     7861 agtatatttg taatgcaaaa taaacttcaa actacatgtg ataaattaga cccagaatta
     7921 acaatgaaac aatggttact tttagctatt gcggactctg tagatgaaac tcttacatta
     7981 accaaacttg gagaattaat ggggtgctca agacaaaatg taaaaaaact agctattgct
     8041 ttagaaaaga aaggttttat acaaattgag caaaatgaaa aagattcaag agctatctgt
     8101 cttgtgacaa aagatagagt gcaagagtat tctaaaaaag taagaggtat gcaggaaaaa
     8161 gtattacagc ttttatttga agattttaca gagaaagaag tggaacagtt attttttgga
     8221 attatgaaat taagtatagg aattgaaaat gtgaaaaatt atgtagaaaa taatgacgtt
     8281 ggagaataag caagtatcaa atcaactttg tatgacatca gagagggggg taatttatat
     8341 gaaaagtgta gtagtgattt ataagagtaa gtatggttca acaaaaaaat atgctaaatg
     8401 gctttcagaa ttattgtctt gtgatatttt tgaaactaag aatattaata tagaaaaggt
     8461 tatgaagtat gatacgatta ttttaggagg aggtctttat gcttgtaata tagcgggaat
     8521 ttctttctta aaaaaaaatt ataaagattt gcagaaaaaa aatttagtag tatttggcgt
     8581 aggagctgct ccatatgatg atgaagtaat aaagaaatta agagaagtaa actttaagga
     8641 tgaattaaac aaagttcctt gcttttattg tcgtggggca tgggatgaga caaaaatgtc
     8701 ttttatagat tatactcttt gtagtttttt taaaaaatct atagctaaaa aagaacgtca
     8761 aggtcttaaa ccagcagaag cacctttatt gtctggagaa gcctttgatt ggtgtaataa
     8821 agaaaattta actccaatac ttaattatat aagaaaactt taagaggtat atatttataa
     8881 ttatttatta tctaaagtta gatttcatag aaact
//
LOCUS       DAMJWO010000114         8724 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.118, whole genome shotgun sequence.
ACCESSION   DAMJWO010000114 DAMJWO010000000
VERSION     DAMJWO010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8724
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.118"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(160..492)
                     /locus_tag="PC366_003340"
     CDS             complement(160..492)
                     /locus_tag="PC366_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HDF2578824.1"
                     /translation="MNTREMKEYRGFYNKKLSETDEFFRVFGSLDDKTYSEGAISKKN
                     KELMGLAISILSRCDECICYHIEGCINSGASKDEIIEAIKIGVIGGGSITYPNARFAI
                     KILEEFNI"
     gene            complement(736..1377)
                     /locus_tag="PC366_003341"
     CDS             complement(736..1377)
                     /locus_tag="PC366_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HDF2578825.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVILQI
                     LMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKQNYSVGIILPWTLDDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFIYSYLMYKISGKNN"
     gene            complement(1358..1651)
                     /locus_tag="PC366_003342"
     CDS             complement(1358..1651)
                     /locus_tag="PC366_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2578826.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            2045..2104
                     /locus_tag="PC366_003343"
     CDS             2045..2104
                     /locus_tag="PC366_003343"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578827.1"
                     /translation="MIEYIYYYNNKRIKKINLA"
     gene            complement(2620..3288)
                     /locus_tag="PC366_003344"
     CDS             complement(2620..3288)
                     /locus_tag="PC366_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HDF2578828.1"
                     /translation="MPVLMAIGVPVHLAIGTNKFAASAGCISSAYRYAKSGKINNDLL
                     KKLVPFTIIGSVLGVRCVLSISEEILNVLVVVMILIVAIYTFISKNLGQEDNFEAVNK
                     KNLRLGMLMALIMGFYDGFFGPGTGTFLTFGFIKIYGYDFLHASANTKILNLTSNITS
                     LLLFMINGQVDYKIAIVFALVMIMGAYVGAKVAIKKGSKMIKPIFLVMALFMVVKLVY
                     QTLV"
     gene            complement(3233..3373)
                     /locus_tag="PC366_003345"
     CDS             complement(3233..3373)
                     /locus_tag="PC366_003345"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578829.1"
                     /translation="MFSVIFLCIGGFLAAFVDSIAGGGGTYKHACSYGNWSASTSCHW
                     YK"
     gene            complement(3432..5087)
                     /locus_tag="PC366_003346"
     CDS             complement(3432..5087)
                     /locus_tag="PC366_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2578830.1"
                     /translation="MVDFIESNNEVQKFDWGEVMWIHEPSKTQFNRLSAGIVRFFPGN
                     CQEKHFHLSEEQLLYVIQGEGIQMIDGKKVNIKETSIVYCPPYSEHEIINTGKIDLVI
                     LITYVPHKFSSLRQIPIVFSENNIQELVNVNIIENLANQISNILKLRISVYDLKYKGI
                     FETKKENKFCDICKNIKPCTKKLVKSINNDNFEKVYHCEYGVSSLEIPIVLEENIVGY
                     IECGNFIVYKSIDIDKNLSELSSSSGIDIKYINKIYNEFPLNPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKSRKENIRLEEALKKANSRLLEEEYIINPIDMFN
                     NSSKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLRYNDVRDTIQEMIFVLSRTVLRD
                     LEDLKLISYLRNKYNKKISLVDSDEDLWNVLFEFSKECIDKNRAFWRKDKGNLIENIN
                     EYIKKYYKENINLNSISDVFFISPNYLSSIFNERNKVSITEYINLLRIEESKKYLLDR
                     SMSISDICKKVGFNNSSYFSQIFKKFNSITPNEYRKNMLDNKY"
     gene            complement(5316..5684)
                     /locus_tag="PC366_003347"
     CDS             complement(5316..5684)
                     /locus_tag="PC366_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2578831.1"
                     /translation="MKYSITDVSKITKISSSAIRFYEEKGLLLPINRKPSGVRYFSEE
                     DVERLIFIKELKNTGLSIKDIHECFHFCDMGDGTIDKRIQLFQQHKQNIKNKIHELES
                     CMDKIDEKIYYLKEKKMCKK"
     gene            5833..6627
                     /locus_tag="PC366_003348"
     CDS             5833..6627
                     /locus_tag="PC366_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase"
                     /protein_id="HDF2578832.1"
                     /translation="MEKYATMIKEKLNEGKVLCGVAVSLSDSVVSELIGISGYDFIWI
                     EGEHSALDRKDIQQHMIAAHAGGAASLVRLVNSDPDLVKPIMDMGTDIICFPFINTVE
                     DAQKAVAACTYPPNGIRGYNPQRASYYGNMNYFDYVKNANNETLKMMLIEQKAGYDNL
                     EEIVKVEGIDIIALGPGDLSLDMGFSGYMNRIEIKDMISHAAEICKKYKMPFIIFPTI
                     EKKSIEEWVNIGANMLCFAQDTTFITYVINQLLSFYNEIVPIQKQH"
     gene            complement(6780..7208)
                     /locus_tag="PC366_003349"
     CDS             complement(6780..7208)
                     /locus_tag="PC366_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF2578833.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFVAEGVKLKGKTPEVLDVSLLKPS
                     DLKEEDKFALGCPSMGAEQLEEGYMEPFVSELESMVSGKQIGLFGSYGWGNCEWMRDW
                     EERMQNAGATIIGGEGITAMEDPNEEAKDECIELGKTLAE"
     gene            complement(7684..8622)
                     /locus_tag="PC366_003350"
     CDS             complement(7684..8622)
                     /locus_tag="PC366_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HDF2578834.1"
                     /translation="MNKRMKLIPYEINENLRGAKNKFPYGIKQMNARGMWDEGYTGKN
                     IVVGIIDTGCDISHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKNLK
                     NAVMQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMDNKLAIMSGTSMSAPYVSGSLALIKEWAREEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNNSKR"
BASE COUNT         3032 a         1418 c          841 g         3433 t
ORIGIN      
        1 atgatgtaaa taatttaaaa ctactatatt atttaaaaat ttatatttat atatgcaatt
       61 ctaaaaactt aataagaagt gaacttagaa aataaagctt aatttcaaag acttaaatag
      121 aatattatta ttagtctaaa taaactacgt gtatcaaaat tatatattaa attcttctaa
      181 aatttttatt gcaaatcttg cgtttggata tgtaatagac ccgccaccaa ttacacctat
      241 ttttatagct tctataattt catctttact tgctccagaa ttaatacaac cctcaatatg
      301 ataacaaata cactcatcac atcggcttaa aattgaaata gctagtccca ttaattcctt
      361 atttttttta cttatagccc cttctgaata agtcttatca tcaagacttc caaatactct
      421 aaaaaactca tctgtttcac ttaatttttt attgtaaaat cccctatatt ctttcatttc
      481 tctagtattc atcttctacc tcctatgttt ttcttataag agtatcacac tgtacttata
      541 ttttcaatat taaatacaaa ttttcatttt atgttcatta gcctaattta tattattttt
      601 tgaaatctca ataagttatc atataagtaa gattttttca gaactaaaat agaaatctta
      661 gtaatttctt tattatctat ctcagttctg aaatatatta ttcttatcca aacattatta
      721 tagtgattaa ttatattagt tatttttacc tgaaatttta tacatcaaat aagaatatat
      781 aaatggtagt attacaatta caaagattac aaagatatta taaaaaggaa tattaataaa
      841 tgcattaata attaataata ttccaccaat aagccaaatc catccagcta aatggtgtgt
      901 cttattccaa ttatcttcat catcaagagt ccatggcaaa attattccta ctgagtaatt
      961 ttgtttacat ttaggaagat agtttccaaa taaaataact attattccta aaattaatcc
     1021 tgtataaaaa ttagactcca aactaactcc tgttgaatat aaaaccatca gtatttgtag
     1081 aattactgaa agtatagcaa ctccccattt tgataaattt tgtataacat ttgaaaaatt
     1141 agctttttta ggctcattct caagtctaaa ccatgtatac aaatggatac atagcattaa
     1201 caatggtaca ccaaaagctg ctataacctt tggagcataa ttatctggat ttccataatt
     1261 atcaaaatga attgcaactt catttggtaa tctattataa aaatatattg atacaataaa
     1321 tggtataaaa catattaaag tagataaaat aaattgttta tttatcgctt ttttcattat
     1381 ctttttctcc cttctccata aattgtgaaa accaaagcat aacctcttcg aaaactgaaa
     1441 tatttatttc gtagaaaata aagttcttat actttgtttc aaatatgagt cctgcctttt
     1501 ttagttgaga tagatgataa gaaattgtag cattcgtcat attaaatttt tcactaattt
     1561 ctcctgctga cattttattc tccctcaaca taaccaatat ttctcttctt atagggtctg
     1621 aaagagcttt gaatgtttct ggaaacccca acaccatcac ctcgctattt agaatttcat
     1681 ctaaatagaa tataacataa catccatttt atttcaataa ctatttagaa aaatttctaa
     1741 atagttattt ccaaatattt attgaaaatt ttcatattaa gattctcaat ttacttaagt
     1801 cgcttttata taatcttatt ttatctaatt tttttaattt aacaaaagtg tattgcacca
     1861 caattgttaa agcaaaaacc taatgactga tatacttata tatattacat atacttttaa
     1921 tttcaaatta aaagtagcta aatccaattt aaaaagtagt taagtcctat ttaaatagaa
     1981 aagaatgaaa taagaaatat actgtataaa aatgcataaa aacctctact aattagatac
     2041 aactataata gaatatattt attattataa taacaaaaga attaaaaaaa ttaatttagc
     2101 ataaccttgt taaatataga tttgaatatg aatttaaagt tatgtaaaat taaaaataca
     2161 ggaatgaaaa ttccattcct gtataaaatc taacttttga gtctcaatac aatcttattt
     2221 tgagacaatc ttttttgttt tatattttct tatatttaaa atataacgca tatcttatgc
     2281 aacatattca tatttttctt tatattcttt catcgcatca ttccaagcgt cttgtactgt
     2341 tacacctctt ttattagcaa ttttttgtgc cagttcaatt atcttcatag ctcttcttga
     2401 tatgttcata aacattcctc ctacaaatta ccatatattt catatatata aatcaaggtt
     2461 atatttttat gatatataat ccttctattg taatattaca atttatatgt gtattatata
     2521 tgaactatat tagaagataa ttagaatttt tataaagcta tatgattaga ttaaatataa
     2581 aagctttaca attacttata aatttaaaaa gtctataaac taaactaatg tttgatatac
     2641 caattttacg accataaata atgccattac taaaaatatt ggttttatca tctttgaacc
     2701 tttctttata gcaactttag cacctacata agctcccatt atcatcacta atgcaaacac
     2761 tatagcaatt ttataatcta cttgaccatt tatcatgaat aataacaatg aagttatatt
     2821 acttgttaag tttaatattt ttgtatttgc agaagcatgt aaaaaatcat atccatatat
     2881 ttttataaat ccaaaagtca aaaaagttcc tgtacctgga ccaaaaaaac catcataaaa
     2941 acccattata agagccataa gcatccctag tcttaaattt ttcttattaa cagcttcaaa
     3001 attatcttct tgacctaaat ttttagaaat aaaggtgtaa atagccacta ttaaaatcat
     3061 aaccacaacc aaaacattta atatctcttc acttattgat aatacacatc tcacacctag
     3121 aacactacca ataatagtaa atggtactaa tttttttaaa agatcgttat taatttttcc
     3181 agactttgca tatctatagg cactacttat acatcctgct gatgctgcaa atttatttgt
     3241 accaatggca agatgtactg gcactccaat tgccataaga acaggcatgc ttataagtcc
     3301 ctcctcctcc tgctatagaa tctacaaaag cagctaaaaa cccccctata cataaaaaaa
     3361 taactgaaaa cataaaattc ctccatcatt ctctttcaat ttttcttaca atatatatta
     3421 tataatctta tttaatactt attatccagc atattctttc tatattcatt tggagttata
     3481 ctattaaact tcttaaatat ttgtgaaaaa taactactgt tattaaaacc tactttctta
     3541 caaatatcac taatactcat gcttctatct aacagatatt ttttagattc ttctatccta
     3601 agaagattta tatactcagt tattgaaact ttatttcttt cattaaaaat agaactcaaa
     3661 taatttggac ttataaaaaa aacatctgat atactattca aatttatatt ttctttataa
     3721 tattttttta tatattcgtt tatattttca attagatttc ctttatcttt tctccaaaat
     3781 gctctattct tatcaataca ctctttggaa aattcaaata atacattcca taaatcttca
     3841 tcactgtcta caagtgatat ttttttatta tatttatttc ttaaataaga tataagtttt
     3901 aaatcctcta aatctctaag cactgttcta gacaatacaa atatcatttc ctgaatagta
     3961 tctctaacat cattatatct taatttgttt gtatctatta gattataaac accttctaaa
     4021 ttcatatttt taatttcttt ttcaatataa agttctaatt caaagggata ttcttttgaa
     4081 gaattattga acatatctat cggattaata atatactctt cttctaataa tctactattt
     4141 gcttttttaa gtgcctcttc aagtcttata ttttcttttc tactctttaa tatctcctca
     4201 tcttttatac taagttgatt ttcaaaaaaa ttcctcttag ctatttcctg aataaattca
     4261 gacatcatta ataaattttc ttttaataca tataatctac ttttaggatt taatggaaat
     4321 tcattgtaaa ttttgtttat gtattttata tcaataccag aactacttga taattcagat
     4381 aaatttttat ctatatcaat agacttatat actataaaat taccacattc tatatatcca
     4441 actatatttt cttctaatac tataggtatc tctaaactgg aaacaccata ctcacaatgg
     4501 tacacttttt caaagttatc attatttatg cttttaacaa gttttttagt acacggtttt
     4561 atatttttac aaatatcgca aaatttattt tctttcttag tctcaaatat tcctttatac
     4621 tttaagtcat atacagatat tctaagcttc aatatattag atatttgatt tgcaagattt
     4681 tcaattatgt ttacattaac taactcttgt atattgtttt cagaaaatac tataggtatt
     4741 tgtctcaaac tcgaaaattt atgaggaaca taagtaatta atattactaa atcaatttta
     4801 ccagtgttta taatttcatg ttctgaatat ggtgggcaat aaactataga tgtttccttt
     4861 atattgacct ttttaccatc aatcatttgt attccttctc cctgaatcac atataaaagc
     4921 tgttcttcac ttaaatgaaa atgcttttct tggcagtttc ccggaaaaaa tcttacaatt
     4981 ccagcactaa gtctattgaa ttgtgttttt gatggttcgt gtatccacat aacctctccc
     5041 caatcaaatt tttgtacttc attatttgac tcaataaaat ccaccataaa ctcacctcgt
     5101 agtttttatc taaatatttt tttattcctt taaatatctc cttataatat acattatcat
     5161 aattttcttt tttattgtat agataaatag ttatatagaa cattgtccaa ttcttcctaa
     5221 aaatatagtg taaaaaatct ttcctcaaat gtttccaatt gaatttactc tttatattag
     5281 aaaaatcaaa aaattatttc tttattctat aaggattatt ttttacacat ctttttttct
     5341 tttaagtaat atattttctc atctatttta tccatacaac tttctagttc atgtatttta
     5401 tttttaatgt tttgcttatg ttgttgaaat aattggattc ttttatctat tgtaccatct
     5461 cccatatcac aaaaatgaaa gcattcatgg atatctttaa tagataaacc agtatttttt
     5521 aattctttga taaatattag acgctctaca tcttcttcag agaaatagcg aacaccactt
     5581 ggttttctat tgataggaag taataaacct ttttcttcat aaaatcgaat agcagatgaa
     5641 gaaatttttg ttatttttga tacatcagtt atagaatatt tcataatctc tacctcccta
     5701 aattttatat gaataagaat attataaaaa taccttatac agtagtcaac aaaaaagtat
     5761 tgacttcaag ttaggttgaa gttgtactct ttgaagtgta aaagaaaact tacaaaagaa
     5821 aggatgatat aaatggaaaa atatgcaact atgattaaag aaaagctaaa tgaaggaaag
     5881 gtcttatgtg gagtagctgt ttcactgtct gattcagttg taagtgagtt aatcggtata
     5941 tctggatatg attttatttg gattgaagga gaacatagtg ctttagaccg taaagacatt
     6001 cagcaacata tgatagctgc ccatgctggt ggtgctgctt ctttggtacg attagtaaac
     6061 agtgaccctg accttgttaa gcccataatg gatatgggaa cagatattat ttgtttccca
     6121 tttattaata cagtagaaga tgcacaaaaa gccgtagcag cttgtactta tcctccaaac
     6181 ggtataagag gatataatcc tcaaagagcc tcttattatg ggaatatgaa ttattttgac
     6241 tatgtcaaaa acgcaaacaa tgaaacatta aaaatgatgt taattgaaca gaaagcaggt
     6301 tatgataatc ttgaagaaat agtaaaagtc gagggtattg atattatagc attaggccct
     6361 ggtgacttat ctttagacat gggtttttcc ggatatatga atagaattga aataaaagat
     6421 atgatttctc atgctgctga aatatgcaaa aaatataaga tgccctttat tatttttcct
     6481 acaatagaaa agaaaagtat tgaagaatgg gttaatattg gagcaaatat gctttgtttt
     6541 gcacaagata ctacctttat cacttatgtt atcaatcaat tattatcttt ttataatgag
     6601 attgtaccaa ttcaaaaaca acattaaatt ataaatctaa ttttatatta aaagagacta
     6661 atattttatc tatctctatt aaggatattt tcttatgtat cataatatta gtctctctta
     6721 ttattatata ctgctatcat cattagttgc tatttatact atttttataa tatacaaatt
     6781 tattcagcta acgttttgcc taattctata cactcatctt ttgcttcttc atttgggtct
     6841 tccattgctg taattccttc tccaccaata attgtagcac cagcattttg catacgttct
     6901 tcccagtctc tcatccattc acaatttccc catccatatg aaccaaataa tccaatctgt
     6961 ttacctgata ccatagattc taattctgaa acaaatggct ccatataccc ctcttctagt
     7021 tgctctgctc ccatagatgg gcaacctaat gcaaatttat cttcttcttt taaatcactt
     7081 ggtttcagta agctcacatc taaaacttct ggtgtcttac cttttaactt cacaccttca
     7141 gccacaaaat ttgccatttt ttcagtattt cctgttccac tccaataaac aatatatatt
     7201 ttactcattt ttacctcctg tagtattttt taattaatca atagttagtt atagctaact
     7261 aacatctaaa aaacaaaaga tttctttatc tgaaatctct ttatttttct aaatatagaa
     7321 tatcacaatt gattttgaaa ttcaatattt attgataata tttatcattt atattttata
     7381 ttcattttat aatatcaaaa cactgtatcg tatttctaat ctttcataga aaaatttcta
     7441 acttatagta cttttgcatc tcttataaat cttttatatg tataagtaca tagaaaaaca
     7501 caccttttcc agatgtgcta tctataatat cgtatattta tttttcaatt ctaactagct
     7561 aatatgttta taaattttat cacttaatac ctttatacat tgatgtaaaa tcttacacct
     7621 aagtaatttt tattatttgt ctcgactcta tataatatag ctattttatc atcaaatcaa
     7681 aaattatctt ttgctattat tcttgtattt ataaagattt aaatataagt atccatttcc
     7741 ttgttccgtt ctaggtattc caagcgctct cgtacatttt attaattgtg catacagttc
     7801 agcttcatct aaatctcttt caaactcctc tcttgcccat tctttaatta gtgctaatga
     7861 gcctgatacg tatggtgcac tcatactagt accactcata atagcaagtt tattatccat
     7921 ataagtcgat ataatatttc ttcctggagc caccaaatct attgtagtat ttgaattact
     7981 aaacttttca accaaatagt tttcatttat tgcacctact tctattacct cagcataact
     8041 ggctggataa ctatactcac ttgtactaga atcaccatct ccattattac ctgctgcaca
     8101 cactacagaa atattatttt ttactgcttg catgacagca ttttttaaat tcttatcatc
     8161 tttgtttccc ccaagagaca tagatataat atcaaccttg ttatttacag caaagttaat
     8221 agcattaatt atactttgat atgttccggt accatcttta tttaatgctt ttgctattaa
     8281 taatttacaa tctggagcta ctcccataac ttcattatta tagttagatg cagctataat
     8341 acccgccaca tgagttccat ggccattaaa atcctcatat atatttttat ttccattact
     8401 gtcatcacta aaatttgcac caccaattat ttttcctttt aaaagaggat gagatatatc
     8461 acaacctgta tctattatac caactacaat atttttacca gtataacctt catcccacat
     8521 tcccctagca ttcatttgtt ttattccata tgggaattta ttttttgcac ctcttagatt
     8581 ttcatttatt tcatacggaa ttagtttcat tcttttattc atcatatatc ctcctaaaaa
     8641 ttttattgct tataaaaatc atgaatttta ttttataata ggtttataaa tcaaattaaa
     8701 acctatatct acttatttat attt
//
LOCUS       DAMJWO010000115         8680 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.119, whole genome shotgun sequence.
ACCESSION   DAMJWO010000115 DAMJWO010000000
VERSION     DAMJWO010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8680
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.119"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            16..2193
                     /locus_tag="PC366_003351"
     CDS             16..2193
                     /locus_tag="PC366_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2578835.1"
                     /translation="MYNKYNNLYLLLGKENVNMDSYRQLKAKIPCKETGIEIKRTLCD
                     ICSPGVHCGIDAYVKDGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKPISWDEAYREIAEKLNRVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLI
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQKDLIDREYIE
                     KHVHGFNEYKEYVKLFDLDTVSRITGVSKDNIVKAVEMLSQGPFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFPNSGRLFKALHSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANVMNIDDDLLKAGYEASIRHMFKKTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDNEYTHLLTSGARISNAL
                     HSRLHDIKLSRILKNEASCDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYRESDINSIIDDNFDPYSGFPAYRSCKCKIEKMNR"
     gene            2207..2629
                     /locus_tag="PC366_003352"
     CDS             2207..2629
                     /locus_tag="PC366_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2578836.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GENIEYFSLACIHCNEPKCLGACPKNCFKKEEGFVVLDNQNCIGCKLCEKACEYGALI
                     YGNDGKANKCNGCIERYKCGMDSPCVMVCPTGALKFNK"
     gene            3036..3839
                     /locus_tag="PC366_003353"
     CDS             3036..3839
                     /locus_tag="PC366_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDF2578837.1"
                     /translation="MKKLKLIIMLALVLALLITGCSSGNNKNKEEQKTIRVATSGTYY
                     PFAFKDKDKLKGFEVDFWDEFAKRTNCKVEWVLTDFSGLFGLLEADKADVVSAQLTAT
                     PEREKKYAFSDAYNYSGTNIIVREDDTSIKSIDDLVGKKVGVGTGAVANEILKEKYPN
                     DEIKIVNYSSATLKGNYQDLEMGRLDAVVAQDVEALIAIKEQKLNLKMVEPPIQFGAC
                     SFAIQKNEKGEKWTKEINEVIEEMHKDGTLTKISEAWLGKDITKEPINE"
     gene            3832..4500
                     /locus_tag="PC366_003354"
     CDS             3832..4500
                     /locus_tag="PC366_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF2578838.1"
                     /translation="MSNFNFEFCLSIFPFLIKALGITILISIVAFFLSILLGVILAFF
                     TQTKSKVLQYITRVYVSFFRGTPLLIQIFFFYFGFPMIFSFMKDCSPYLAIVICLGVN
                     SSAYMTEIIRASIESVDKGQQEACYAFGLSKYQSMVKIILPQAATSAVPPIVSCTLDI
                     IKGSSLGLTIGIQDLMGVAQVEAASSFKYFEIYMITILIYWAVSIILSNIQSKVEKRI
                     GKAY"
     gene            4736..5398
                     /locus_tag="PC366_003355"
     CDS             4736..5398
                     /locus_tag="PC366_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDF2578839.1"
                     /translation="MIFNMKYFLELFPIIMKSFNVTVILAISSLVFSLIIGTIVALSS
                     YYKVKVLNQICKVYVSIFRGTPLMPQLFFLYFGLAYMNDFVKNMDPVFATSIVLSLNM
                     GAYMSETIRASILSIDKGQIEAAYVMGLTNLQTMKRIVIPQAVRVALPSLFNNFIDLI
                     KGSSVAFVVGVNDIMGAAKSQGALSFKFFEVYGAVMVIYWCIITPLGWGQKKLEKKIS
                     NY"
     gene            5458..6255
                     /locus_tag="PC366_003356"
     CDS             5458..6255
                     /locus_tag="PC366_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2578840.1"
                     /translation="MVKRNIIKCLVAVLSLTFVVAGCSKKEEVKDEKVITVASSNSAD
                     PYSYVDNGEHKGFEVDMWKEIGKRSGYKIKMEPTGFSSIFGMLDSGKVDVAANFFGMS
                     KERLEKYDASIPYGSDSVCIAVKDGNNEINKLEDLKGKVVAVSEGSQGQQVAASVNKD
                     NLFEEKVYGDGTNGLQDLDLGRVSAWIDAELTVVGDAKKANMKVRVLDEKLSVTNIAY
                     FFKKNDEKSKTIKEDVNKAIEEMLSDGTVKKISEKWFGMDVSADIQK"
     gene            6388..7563
                     /locus_tag="PC366_003357"
     CDS             6388..7563
                     /locus_tag="PC366_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDF2578841.1"
                     /translation="MIETKIKSIALKNREKIIKIRRQIHSNPELAFKEFKTSKLIKEE
                     LNKLKIEYIDVAGTGVLATIKGKNNGGKTILLRADMDALPIKEENDLEFKSINDNMHA
                     CGHDAHVSWLLGTAMILNDIKEELNGNVKLLFQPGEEKGGSDIVIKENVLEGVDALAT
                     GHCWPTIESGKIGIARNCAMAATNTFEITIIGKGGHGAEPHNCIDPIAVGNAVYSSIQ
                     QIVSRKIDPVVPVVVSVCSFNSGVSKNIIPDVCTLQGTIRAISKEQVIEVSKILENIV
                     RNVCRAYGADCKFEKSTGGDAVINDKNMIELGRESACKILGVENVEIIDFPAMTGEDF
                     AIYMKEKPGLFMYIGVGNKEKNINYRLHSNKFNIDEKCLSIASSLFSQLAVDYLCQL"
     gene            7672..8421
                     /locus_tag="PC366_003358"
     CDS             7672..8421
                     /locus_tag="PC366_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDF2578842.1"
                     /translation="MIKVENLHKSFKGTEVLKGINLEINQSEVVAILGPSGTGKSTLL
                     RCLNYLVEPTKGKIMIGDVKVDVEKATKKDIANLRKHTSMVFQNYNLFKNKTALENVM
                     EALIVVHKKSNKEAREISLKLIDKVGMLDRKDFYPSKLSGGQQQRIGIARAMAVNPNV
                     ILFDEPTSALDPELVGEVLSVIKSLAKEGITMLIVTHEINFAKEVADKIIFMDNGVIA
                     EEGTPDEIFNNPKNERTAKFLNIVRKEEVFS"
BASE COUNT         3451 a          875 c         1603 g         2751 t
ORIGIN      
        1 atttgaataa aaagaatgta taataagtat aataatttgt atttattatt gggaaaggaa
       61 aatgttaata tggatagtta tagacaactt aaagctaaaa taccctgtaa ggaaacaggt
      121 atagaaataa agaggacttt atgtgatatt tgttctccag gagtacattg tggaattgat
      181 gcatatgtta aagatggtaa agtaataaaa atagaaggta caaaagaaca tccaatgaat
      241 aaagggttgt tatgtaccaa aggtctttgc aatagagaat atatatatag agaagataga
      301 ataaaaacac ctctaaaaag aattggaaaa agaggtgaag gaaaatttaa accaatatca
      361 tgggatgaag cttatagaga aatagcagaa aaattaaata gagtaaaatc tgagtatgga
      421 gcaaagcatg tagctttttt tacgggttat ggaaagtggt atagaccttt tttgcaaagg
      481 tttgcatctt catttggttc acctaattat ggtacagaat ctagttcatg ttcaacatca
      541 gcacagatgg ctggaaatgt tgctactgga agaaacttta caatgcaaga tatggagaat
      601 gcaaaaactt atttagggtg gggatttaat ccatactact ctaaattttt aaatagtgtg
      661 aatctaataa aattaaaaga aaaaggtcta aaatttataa ttgtagaccc tagaataaca
      721 ccgacaactc aaaaactagc agatttacat ttaagaatta aacctggaac tgatggagct
      781 ttagctcttg gaatggcgaa tctatttata caaaaggatt taatagatag agaatacata
      841 gaaaagcatg tacatggatt taatgaatat aaagaatatg taaaattatt tgatttagat
      901 actgtaagta gaattacagg agtttctaaa gataatatag taaaagctgt tgagatgttg
      961 tcacaaggtc cattttgtat aaatgaaagt gcagctccaa tagttcatca tcaaaatgga
     1021 tttcaaaact atagagcaat gatgtcttta tctgctataa caggtaatta tgatagaata
     1081 ggtggaaaca taccaaaaca agattacttt gctggtaaga taggtggatt ccaaacacta
     1141 gaaaaagagt ttgtaaaaga agttctacct aaaaatataa atgaaagaat tggtggagaa
     1201 agatttcctc tatggaatga aatggtaact caatttcaag ctatggattt acctaggcaa
     1261 atagaagaaa agacaccata tgaaataaga gctttgtttt gtcatgggat aaatgctaga
     1321 atgtttccta attcagggag actttttaaa gcgttgcata gtgtagattt ttttgtgaat
     1381 atagatttat ttatgacaga tacatcaaaa tatgcagata tacttttacc tgcgtgtaca
     1441 tcatttgaga gagaagaatg taagagttac ccaggagggt atattacata taccaaaaaa
     1501 gttattgata aattatacga ttcaaaatca gatgtagaaa tactttcaga tttagcaaat
     1561 gttatgaata tagatgatga tttattaaaa gcaggttatg aagcaagtat aagacatatg
     1621 tttaaaaaga cgtgtgtaga tgtagataaa cttaaagaaa gtgatttacc attaaaatgt
     1681 aaagatttta agccatatat agtaggctca tatacaagag aggggtatga tactagcact
     1741 tctaggtttg aattaaaatc tacaattatt gaaaaatata aagattttgg actggatgca
     1801 ctaccaacat atagaggatt taatgataat atagataatg aatatactca tttattgaca
     1861 tcaggagcaa gaatttcaaa tgcactacat tcaagacttc atgacatcaa actttcaaga
     1921 atattaaaaa atgaagctag ttgtgatatt tccagcttgg atgcaaaaga attgggtgtt
     1981 atcagtggag attatataaa aataactact aagataggaa gtttggatgt aaaagtcaat
     2041 gttactgata gagtcttata taagaatata catatgtatc atggatatag agaatctgat
     2101 ataaatagta ttattgatga taattttgac ccttatagtg gattccctgc gtatagaagt
     2161 tgcaagtgta agattgaaaa aatgaataga taaatggaga gatataatga aaagtttatt
     2221 taaatttaat aaagaattat gtacagcatg tggagcatgt ttgcttgcat gtatagacca
     2281 aaatgataat aatatagaca atggtgaact ttttagacat gtatttacaa tagaggaagg
     2341 tgaaaatata gaatattttt cattagcatg tatccattgt aatgagccaa aatgtttagg
     2401 tgcatgtcct aaaaattgtt ttaaaaaaga agaaggattc gttgtattag acaatcaaaa
     2461 ctgtataggg tgtaaacttt gtgaaaaagc ttgtgaatat ggagccttaa tttatggaaa
     2521 tgatggtaag gcaaataagt gtaatggttg tattgagaga tataagtgtg gtatggattc
     2581 accttgtgta atggtatgtc ctacaggagc attaaaattt aataaataaa ttaaatatag
     2641 agagtgactt atacttggta taagatattt ttacaaaaag ctatattgag tttgttataa
     2701 taaaaactca atatagcttt tttatggata tagttggata ctataatgtg atttttagta
     2761 atagtttttt gctattggac aaagactgta aaacatatta aacttatgtt gttcaaagtc
     2821 gaagtataat ataataacta gaaaattgat ttatagtgtt ataaaagcaa atttagtaag
     2881 gtataaaata agaggcaatc ttttactaca gtatcaatat ttgggagtta tgttatggca
     2941 gagccattaa acaattataa tggtacaagt gattcaacct ttgaaaatgt attatataaa
     3001 aaattaaaat aagattaaaa aggagagaat aaattatgaa aaaacttaaa ttaattatta
     3061 tgcttgcctt ggtattagca cttttaatta caggatgttc atcaggaaat aataaaaata
     3121 aagaagaaca aaaaactata agagttgcaa catcaggaac atattaccct tttgctttta
     3181 aagataaaga taaacttaaa ggatttgaag tagatttttg ggatgaattt gctaaacgaa
     3241 ctaattgtaa agttgaatgg gtattaactg attttagtgg attatttgga ttattagaag
     3301 ctgataaagc agatgttgta tctgctcaac ttactgcaac acctgaaaga gagaaaaaat
     3361 atgctttttc agatgcttat aattatagtg gaacaaacat tattgttaga gaagatgata
     3421 ctagtataaa atcaatagat gatttagttg gcaagaaagt aggtgtgggt actggagcag
     3481 tagcaaatga aatactaaaa gaaaagtacc caaatgatga aataaaaata gtaaattatt
     3541 caagtgcaac tcttaaaggg aattatcaag atctagaaat gggaagatta gatgcagtag
     3601 ttgcgcagga tgttgaggct ttaatagcta taaaagaaca aaaattaaat cttaaaatgg
     3661 tagaacctcc aattcaattc ggagcctgtt cttttgcgat tcaaaaaaat gaaaaaggtg
     3721 aaaaatggac aaaagaaatt aacgaagtaa ttgaagagat gcataaagat gggactttga
     3781 ctaaaatatc tgaagcctgg ctaggaaaag acattactaa ggagcctatt aatgagtaat
     3841 tttaattttg aattttgtct aagtatattt ccatttttga ttaaagcatt gggaataaca
     3901 atactaatat ctattgttgc atttttttta tcaatattat taggtgtaat acttgccttt
     3961 ttcacacaga caaaatcaaa agttttgcaa tacataacaa gagtgtatgt ttcattcttt
     4021 agaggaacac cacttttaat tcaaatattt ttcttttact ttggatttcc aatgatattt
     4081 tcttttatga aagattgttc accttattta gcaatagtaa tttgtttagg tgtaaattca
     4141 tctgcatata tgactgaaat tatacgagca tctattgaga gtgttgataa aggacaacag
     4201 gaagcatgtt atgcttttgg gttaagtaaa tatcagtcaa tggttaaaat aattctacct
     4261 caagcagcta catctgcagt acctcctatt gtaagctgta cactggacat aattaaaggt
     4321 tcttctttag gtctaactat aggaatacaa gatttaatgg gagtagctca agtagaggct
     4381 gcttcaagtt ttaaatattt tgagatatat atgataacga tattaattta ctgggcagta
     4441 tctataatat tgagtaatat acaaagcaaa gttgaaaaaa gaataggaaa ggcatattag
     4501 atttcaatat ttaaaaatgg gatgatgtag atatattatt acttgtaaat aaatttttaa
     4561 ttttagaaaa ataaacttag taatctaaat tattgagaaa atatagtatc aaaatggact
     4621 gtataatcaa gttaaaaaat agtttttcta ttgaaaaaat aaataaaatt ctattgtaat
     4681 ttaatattcg acaaagtttt ataaaaaaca acattaagct agggggactt attttatgat
     4741 ttttaatatg aaatattttt tagaattatt tccaataata atgaaatcgt tcaatgtaac
     4801 tgtaattttg gcaataagtt cattagtatt ttcattaatt ataggtacaa tagtagcatt
     4861 atcatcttat tacaaagtga aagtattgaa tcaaatatgt aaagtatatg tatctatctt
     4921 tagaggtacg cctcttatgc cacagttatt ctttttatat tttggactag cgtatatgaa
     4981 cgattttgtt aaaaatatgg acccagtatt tgcaacatct atagtactta gtttaaatat
     5041 gggagcttat atgtccgaaa cgataagggc atctatactt tcaattgata aaggtcagat
     5101 agaagcagca tatgtaatgg gattaacaaa tttacaaaca atgaaaagga tagtgatacc
     5161 acaggccgta agagttgcac tgccatcatt attcaataat tttatagatt taattaaagg
     5221 gtcttctgta gcttttgttg ttggagtaaa tgatataatg ggtgctgcca aatcacaagg
     5281 agcgttgagt tttaagttct ttgaagtgta tggagcagtt atggtaattt actggtgcat
     5341 aataactcct ttagggtggg ggcaaaaaaa attagaaaag aaaataagca attattaagt
     5401 tattaagaaa atacataaaa gtatttttat ataaaaaatg gtgtgaggag aagagatatg
     5461 gtaaaaagaa atattataaa atgtttagtg gcagttttat cgttaacatt tgtagttgct
     5521 ggttgttcaa aaaaagagga agtaaaggat gaaaaagtta taactgtagc ttcatctaat
     5581 tcagctgacc catattctta tgttgataat ggtgagcata agggttttga agttgatatg
     5641 tggaaagaga ttggtaaaag aagtggatat aagataaaaa tggaaccaac aggttttagt
     5701 tctatatttg ggatgttaga ttctggtaaa gttgatgtgg cagccaattt ctttggaatg
     5761 tctaaagaaa gattagaaaa atacgatgct tctatacctt atggttctga ttctgtatgt
     5821 atagctgtaa aagatggaaa caacgaaatt aataaacttg aagatttaaa aggaaaagtt
     5881 gtagcagttt cagaaggttc tcaagggcaa caggttgcag ctagtgttaa taaagataat
     5941 ttgtttgaag aaaaggttta tggtgatgga actaatggtc ttcaagattt agatttagga
     6001 agagttagcg catggattga tgcagaactt actgttgtag gagacgctaa aaaagctaat
     6061 atgaaggtaa gagtattaga tgaaaaatta tcagttacta atatagcata cttctttaag
     6121 aaaaatgatg aaaaatctaa aactataaaa gaagatgtaa ataaagcaat agaagaaatg
     6181 ctttcagatg gaacagtgaa aaaaatatct gaaaaatggt ttggaatgga tgtaagtgct
     6241 gatatacaaa aataaatact ttaaaattaa aatataaaac tgtgataact atagataagt
     6301 atactaaatt tatctatagt tatctgtgta ttacaatgta tttagattag tctttataaa
     6361 ttaaaatgag ttatggaggt cttgcaaatg attgaaacta aaataaaatc cattgcacta
     6421 aaaaatagag aaaaaatcat aaaaataaga cgacagatac acagtaatcc agagttagca
     6481 tttaaagaat ttaaaacatc caaacttata aaagaagagt taaataaact taaaatagaa
     6541 tacatagatg ttgctggtac aggagtatta gctactataa aaggaaaaaa taatggtggg
     6601 aaaactatat tgcttagagc ggatatggat gcccttccaa tcaaagagga aaatgattta
     6661 gaatttaaat caataaatga taatatgcat gcttgtgggc atgatgccca tgtttcatgg
     6721 ttgttaggaa cagcaatgat tttaaatgac ataaaagaag aattgaatgg aaatgtaaaa
     6781 ttactatttc aacctggcga agaaaaaggt ggttctgata ttgtaattaa agaaaatgta
     6841 cttgaaggtg tggatgcatt agcaactggt cattgttggc caactattga atcaggaaaa
     6901 attggaatcg ctagaaattg tgctatggca gcgactaata cttttgaaat aacaataatt
     6961 ggcaagggcg ggcatggagc agagcctcat aattgtatag acccaattgc agttggaaat
     7021 gcagtatatt catccattca acagatagtt tcaagaaaaa ttgacccagt tgtacctgta
     7081 gtagtgtctg tttgttcttt taattctggt gtttctaaaa atataatacc agatgtatgc
     7141 acacttcaag ggactattag agcgataagc aaggaacaag taattgaagt aagtaaaatt
     7201 ctagaaaata tagtaagaaa tgtatgtaga gcatacggag cagattgcaa atttgaaaag
     7261 agtacaggag gagatgctgt tataaatgac aaaaacatga tagagctagg aagagaaagt
     7321 gcttgcaaaa tacttggagt tgaaaatgtt gaaataattg attttcctgc aatgacaggt
     7381 gaggattttg ctatttatat gaaagaaaaa cctggtttat ttatgtatat aggtgtagga
     7441 aataaagaaa aaaatataaa ctacagattg catagtaaca agtttaatat agatgaaaaa
     7501 tgtcttagta tagcatcttc attattctca caacttgcag tagattattt atgtcaacta
     7561 tagagtacat tcataaaaat atatttagcc tatttttaaa tttaatgcta gtatattaat
     7621 tttgatgtag aacatattat ttattatatt tatttaaaaa ggtggataac aatgataaaa
     7681 gtagaaaatt tacataaaag ttttaaaggg acagaagttc ttaaaggtat aaatttagag
     7741 ataaatcaaa gtgaagtagt agctatactt ggaccatctg gaacaggtaa atctacgtta
     7801 cttagatgtt taaattattt agttgagcct acaaaaggaa agataatgat tggtgatgta
     7861 aaagtagatg tagaaaaagc aacaaaaaaa gatatagcca atttaagaaa acatacatct
     7921 atggtatttc aaaattataa cttatttaaa aataaaacag cattagaaaa tgtaatggag
     7981 gcattgatag tagtacataa aaagagtaat aaagaagcta gagaaatatc tttaaaatta
     8041 atagataaag taggtatgtt ggataggaaa gatttttatc catcaaaatt gtctgggggg
     8101 cagcaacaaa ggataggtat agcaagagcg atggcagtaa atccaaatgt aatattattt
     8161 gatgagccaa catctgcact tgacccagaa cttgttggag aagttttaag cgttataaaa
     8221 tcgcttgcga aagaaggaat aacaatgctt attgtaactc acgaaataaa ttttgcaaaa
     8281 gaagttgctg ataaaattat atttatggat aatggtgtaa tagctgaaga aggaactcct
     8341 gatgaaatat ttaataatcc taaaaatgaa agaactgcaa aatttttaaa tatcgttagg
     8401 aaagaagaag tatttagtta aaagtgtata aattaagtat tagaagatat gtaagatact
     8461 cccattaaat ttataagtta gataataaat ttaatggaag tatcttttta ttattagatt
     8521 tattatttaa tttaaaatta gaaatgtaac tatttgaaaa ttctttttaa aagtatatca
     8581 aaaatatcaa gtacatgaaa aaataatatt tgacaaaata tcatatatgt ttacaaaatt
     8641 aacttgatgg aatgataaag cataggaatt acaatgagta
//
LOCUS       DAMJWO010000116         8492 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.120, whole genome shotgun sequence.
ACCESSION   DAMJWO010000116 DAMJWO010000000
VERSION     DAMJWO010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8492
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.120"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            256..1242
                     /locus_tag="PC366_003359"
     CDS             256..1242
                     /locus_tag="PC366_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2578843.1"
                     /translation="MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMMAIDEELKELKYTSLIINTNRKI
                     RSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPMVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQ
                     ETSIQRSGEMLESENPDIIICATDNIAIATMKEINKRGKNIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            1465..1548
                     /locus_tag="PC366_003360"
                     /pseudo
     CDS             1465..1548
                     /locus_tag="PC366_003360"
                     /inference="COORDINATES: protein motif:HMM:NF012587.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIB"
     gene            1579..3060
                     /locus_tag="PC366_003361"
     CDS             1579..3060
                     /locus_tag="PC366_003361"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HDF2578844.1"
                     /translation="MYKEPKYRTILESIKEELNKLRNISLNDKYKPLFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDATHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNAIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMNKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKRKDKYFMLLGAQTSDKKGVIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDEKDILIFSPQGVEPKGFDYQNIYNVVYAIGNMDLDNLTFEIDTMK
                     ELEKGFDFYAPQTFIKDSQIILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELIKLRYDETSGQNTIKNNINIIENDENVYELNINIKNIDSNKFGLELFSSQD
                     EGVKLEFNKLGNIVTLDRSNFKKVFGVEYGTNRKEYINIDENTNIKVLADRSVLEIFI
                     NDGEVVFTSRIFAKENSNQIRVYSDKIVEYEYTKFKLKQGIEL"
     gene            3086..4057
                     /locus_tag="PC366_003362"
     CDS             3086..4057
                     /locus_tag="PC366_003362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HDF2578845.1"
                     /translation="MKKVISIGEALIDFIPNQNGCKLKNVSEFRRVAGGAPANVSVVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFMTGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLN
                     DIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFIKNL"
     gene            complement(4313..4915)
                     /locus_tag="PC366_003363"
     CDS             complement(4313..4915)
                     /locus_tag="PC366_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDF2578846.1"
                     /translation="MEICILMGSPKKKGNTAAILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKILMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPALWAGKPVALITTCGYRPEKGADIWENGMKRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEKHSRQFAKQIYYILDNSIEVDNC"
     gene            5196..6407
                     /locus_tag="PC366_003364"
     CDS             5196..6407
                     /locus_tag="PC366_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HDF2578847.1"
                     /translation="MYSNEDYKFIEENAPCYIYDETNIIEKCKELKNNILGFDFLYSI
                     KTNPYNKIVKSIAEQGFGADASSTNEVMISSECGVSKYDIYYSSPGKTEIDIETVLDK
                     CIIIADSITEIELINKISKKHNQKVKIGIRINPDFTMDDDSAKSSKFGIDIEDMSSVF
                     KMLSMCDYVSVVGIHIHIKSQVLDFEKLGHYYEKCFFIALNLNKSKYINIEFINFGSG
                     LGVAYDNLRENPLNLKELSKLTQKIVFTNSNTLKSRLLIESGRFIVCKSGNYYVKIVD
                     IKVSRGKKYLIVKNGLNGFMRPIISNLIENITCGVELEGQEPLYTSNHAFSLSVLNNL
                     KEEEYVNVVGNLCTSLDVIANNVKLKKANIGDLISISNAGSYSYSLSPLLFSSYEFPK
                     QYYKRKDGYIE"
     gene            6475..6672
                     /locus_tag="PC366_003365"
     CDS             6475..6672
                     /locus_tag="PC366_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HDF2578848.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILPLYIKQLGVTDVSLI
                     QQYSGIIFGCTFVVAAFFSPI"
     gene            6706..7677
                     /locus_tag="PC366_003366"
     CDS             6706..7677
                     /locus_tag="PC366_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2578849.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGSLIGPTVGGYIESILGLKSTFIITGGLLFVSFI
                     ISILFVVDNFKPKEIKESISIPKEQLNILPNKFLIASIFVTTFITQLALYSIEPIVTI
                     YISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMSDKIGPQKVLLISLLWAGIIF
                     IPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKIAPEEYVGKIFGYNASAQYIGC
                     SSGAFLGGQISAHLGIRTVFFSTSLLLFMNALWMYKFTGLFIKDKTK"
     gene            7864..8241
                     /locus_tag="PC366_003367"
     CDS             7864..8241
                     /locus_tag="PC366_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2578850.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMERKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFESHFKNLEEE"
BASE COUNT         3450 a          878 c         1360 g         2804 t
ORIGIN      
        1 aaaaatcata gccttatttt tatattataa ataaattaga gtatttatca attcatagta
       61 gataaaattg aaattaaata taacaacaaa aaatgaaaat tacaattaat ttaatgttaa
      121 agactcaatt atttggatgt ggaatggata gtacaagtag tatataaaaa gtattgactg
      181 gacaaataac tatattttat tttaaatata taatataatg taataaaata tatcaaatgt
      241 agaaggtgat aacctatgaa aaaaataaca ataaatgata ttgctaactt ggcaggagta
      301 tctaaaagta ctgtatcaag atatctaaat aataaagata tcagtgattc tactaaagag
      361 aaaataaaga caataataga tgaatatgga tatgagccga atgcatttgc tcaaagtttg
      421 agagctaaaa aaacatactt tattggtatt ataacaccgt gtttagattc ttttgtaaaa
      481 tctaaaatta tgatggcaat agatgaagaa ctcaaagaat taaaatatac atcactaatt
      541 attaatacta atagaaaaat aaggtcagaa atagatagta tatcaaagtt agctagtcta
      601 aaagttgatg gaataatact aattggtacc gaaataacta aagaacataa gaatgaaatt
      661 gaaaagttag atataccaat ggttgtagtt ggacaaaaag ttgatggtat caatagcata
      721 gtgaatgatg attatggagc aggatataaa atgggtcaat atattgctaa taaaggttac
      781 aaaaacattg tatatttagg tgttgatgaa agtgatatat cagttggttt aaatagaaaa
      841 aatggagtac ttaatgggtt aaaagataaa gggtatgatg caaaagtatt ttatactgac
      901 tttgaccaag aaacgtctat acaaagaagt ggagaaatgc tagaaagtga aaatccagat
      961 ataataatat gtgcaactga taatatagca atagcaacaa tgaaagaaat caataagaga
     1021 ggtaaaaata taccacaaga tatatctgta gctggatttg ggggatatga tgtattgtct
     1081 attataagcc ctaaacttac aacaataaag tttgaaaata aaaatgcagg taaagtagca
     1141 gcaaatacga tagtgaactt aatacaagaa agaaaagaac cactattaaa ggagattaaa
     1201 tttgaattaa tagaaggtga aagtacaata aataaaaatt aagatacaca ttacatatat
     1261 tagtaatgtg tattttttta ctaaaaaaac tataattcta aaaattagga aaactttttt
     1321 gaaagaaata ttgcatctga aataaattta tgctaatctt taattaaacc ggtttcgaaa
     1381 ccggtttaat taaaccgaaa gaatagcaca atgagtgcaa aaataactga ttgtaacaaa
     1441 gtatcaaagt aattattaga gtacatagga aataaacaaa atataaaagg tgtagcacat
     1501 tgtgtaacaa gattaagaat tgttttagat agtaataata aagcaaatat aaaattacaa
     1561 aagaaaagga ataaaaatat gtacaaagag cctaaatata gaaccatatt agaatcgata
     1621 aaagaagaat taaataaatt aagaaatata tctttaaatg ataaatataa accactattt
     1681 catatacatc cacaacatgg actacttaat gatccaaatg gattagcata ttataatggt
     1741 aagtaccatg tattttatca atggtatcca tatgatgcaa ctcatggaat gaagcattgg
     1801 gcttatgtaa gttctgatga ttttgtaaac tggaatagag aagatgtagc attaatacca
     1861 atcgaaagtt atgaatctca tggagcatat tcaggtaatg cgatagaggt agatggaaaa
     1921 ttgcatatgt attatacagg gaatataaaa tatagtgcag aagatagata tgcatatcaa
     1981 aacttagcta taatgaacaa ggatggtaaa ataactaaat atgaaaataa tccaatagta
     2041 agtgaaatac caaaaggata tacaggacat gtaagagacc caaaagtatt taaaagaaag
     2101 gataaatact ttatgttact tggagcacaa acaagtgata aaaaaggagt tataatagta
     2161 tatgaatcta aaaactctat agattggaat tttaaaggag aattaaatgt aaaaaatata
     2221 gatgaagatt ttggttacat gtgggaatgt ccagattata ttaatataga tgaaaaagat
     2281 atattaatat tttcgccaca aggagtagaa cctaaaggat ttgattatca aaatatatat
     2341 aatgtagtat atgctattgg taatatggat ttagataatt taacatttga aatagataca
     2401 atgaaagaac tggaaaaagg atttgatttc tatgctccac aaacatttat aaaggactca
     2461 caaataatac tatttgcatg ggctggaatg ggagaagttt tataccctac agataaaaac
     2521 aaatgggcac attgtctaac tgttccaaga aaattaaata taaaaaataa caagctattg
     2581 caaatgcctg tagatgaatt aattaaatta agatatgatg aaacaagtgg gcaaaatact
     2641 ataaagaata atatcaatat tatagaaaat gatgaaaatg tatatgagct taatattaat
     2701 ataaaaaata ttgacagcaa taaatttggg ctggaattat tttcatcaca agatgaaggt
     2761 gtaaaattag aatttaacaa attaggaaac attgtaactt tagacagaag caactttaaa
     2821 aaagttttcg gtgttgaata tggaacaaat agaaaagaat atataaatat tgatgaaaat
     2881 actaatatca aagtactagc ggatagaagt gttttagaaa tttttataaa tgatggagaa
     2941 gtagtattta ctagtagaat atttgctaaa gaaaattcta atcaaataag ggtttatagt
     3001 gataaaatag tagagtatga gtatactaaa tttaaattaa agcaaggtat tgaattataa
     3061 aaacacatta taaggggtag aaaagatgaa aaaagtaatt agtataggag aagctttaat
     3121 agactttata cctaatcaaa atggttgtaa attaaaaaat gtatcagaat ttagaagagt
     3181 agcaggagga gctccagcaa atgttagtgt tgttgtagca aagcttggag gaaaatcaag
     3241 ttttatatct aagttaggaa aagatgcatt tggtgattat ataatagatg tattaaatga
     3301 agtaaatgta aatactgatt atgtattgag aacaagtaaa gcaaatacag gacttgcttt
     3361 tgtatcatta aaagaagatg gtaatcgtga tttctcattt tatagaaatc caagtgcaga
     3421 tatgctttta gaagctgatg aggttaaaaa agagtggttt aataattgtc atatcttaca
     3481 tttttgttca gtagatttaa tagatagtcc aatgaaatta gcacataaaa aagcaataga
     3541 atacgcactt gaaagtaata gtataataag ttttgaccct aatataagat tacctttatg
     3601 ggatagtgag caatcttgta aaaaggcaat atcagaattt ttaccttttg ctcatattgt
     3661 taagatatct gatgaagaat tagaatttat gacaggagaa aatgatatag aaaaatcatt
     3721 acataaactc tttgtgggga atgttgaact agtattatat acaaaaggaa aagatggagt
     3781 agatgcatac actaaaaaag taaaaggtat gtgtaaaggg gttaaagtaa atgcaataga
     3841 tacaaccgga gcaggagatt cttatatagg ttcattttta tacaccttat tgtataaaca
     3901 aataacattg aatgatataa aagaaatgaa acaagaaacg ttaaatgagt atttagaatt
     3961 ttctaattat tatgcagctc gtagtacaac tattaaaggt gcgataagtt catatgcaac
     4021 aaaggaagag ataactgaat ttataaaaaa tttatagtag gaatgagtaa taggttttga
     4081 aggaagtaac atgtaaagag tttttaagga tgtttactat gaaaataatt aacatataaa
     4141 aagcaataaa gaggctgtct caaaatagat ataagcctct ttatcattgt tgaaatgata
     4201 aaaaatattt taattattgt tactttttag aagaatatat atcttatttt aaataagcaa
     4261 attatgtaag atttatttat attatcaata ctttacttgg agtattatgt ctttagcagt
     4321 tatctacttc aattgaatta tctaaaatat aataaatttg ttttgcaaat tgacgagaat
     4381 gtttttcttt ttctttattc ataaaattag gtttacctaa atcacgttca acaagcattc
     4441 ctatatattt taactgtgaa tgcttacagt agcgcttcat accattttcc caaatatcag
     4501 cacccttttc aggtctatat ccacatgttg taataagtgc tactggtttt cctgcccata
     4561 gagcggggcc tttctcatta ccatagtact tattcattcc atacaccaat ctgtcaagta
     4621 gtgctttcat tggagaagtg cagtaccaag aataaattgg agtagcaaaa acaattaaat
     4681 cacacataag aattttcttg aaaattttct gaacatcatc tttacaataa catccaaaat
     4741 caaataagtt atcctgacat tttttacaag caatacatgg ctctatttta caatcatata
     4801 accatattac ttcaatattt gaattataat tttctaattc ctcaataaaa ggttttaaaa
     4861 tagcagcagt attacctttt ttcttaggac ttcccataag aatgcatatt tccatattga
     4921 tacctccaca gtattttaaa atagttttta gtgcttaata tagttttagg atactatgag
     4981 aatacgttaa caacaataca ctttgtatat ttttaataaa attgaaacaa attgttttat
     5041 caataaaagt tggaatgtat ctataattaa aaatatttta ggtatgtttt tacatatatg
     5101 tgtgtagtta actatggtaa tttattgtaa aattatctta taggattata attgcttaat
     5161 ttatgattat atttaaaatc ttggaggtaa aaaatatgta ctcaaatgaa gactataaat
     5221 ttatagaaga aaatgcacca tgttatatat atgatgagac taatataatt gaaaaatgta
     5281 aggaattgaa aaataatatt ttaggttttg attttttata ttctataaaa acaaatccat
     5341 ataacaaaat tgtaaaaagc attgcagagc aaggttttgg agcagatgct tcttcaacta
     5401 atgaagttat gatttcatca gaatgtggag tttctaaata tgatatttat tattcatcac
     5461 caggcaaaac agagattgat atagaaactg ttttagataa atgcataatt attgcagata
     5521 gtattacaga aatagaactt ataaataaga tatctaaaaa gcataatcag aaagttaaaa
     5581 taggaataag aataaatcct gattttacta tggatgatga tagtgctaaa tcaagcaaat
     5641 ttggtataga tatagaagat atgagcagtg tttttaagat gttaagtatg tgtgattatg
     5701 tatctgtagt tgggattcat atacatatta aatctcaggt attggatttt gaaaagttag
     5761 gacattatta tgaaaaatgt ttttttatag ctttaaattt aaataaaagt aagtatatta
     5821 atattgaatt tataaatttt ggtagtggac ttggagtagc ttatgataat cttagagaaa
     5881 atccacttaa tcttaaagag ctttcaaaat taactcaaaa gattgttttt actaattcaa
     5941 acacactgaa atcaagactt cttattgaat caggacgttt catagtttgt aaatcaggta
     6001 attattatgt taaaattgta gatattaaag tatcaagagg gaaaaaatat cttattgtaa
     6061 aaaatggact taatggattt atgagaccta ttatttctaa tttaattgaa aatattactt
     6121 gtggagtaga attagaaggt caagagccat tatatacatc aaatcatgcc ttttctcttt
     6181 cagtattaaa taatttaaaa gaagaagagt atgtaaatgt tgttgggaat ctctgtacat
     6241 cattagatgt aattgcaaat aatgttaaat tgaaaaaagc aaatatagga gatttgattt
     6301 caattagtaa tgctggaagt tactcctatt ctttatcacc actattattt tcgagttatg
     6361 aatttcctaa acaatattat aaaagaaaag atggatatat tgagtaaaca ataggataaa
     6421 ttaataaact tagtattatt gaaaaaattt aaaatgcagg gggtgtaatt ctatatggaa
     6481 ttgtggaaaa gaaatttatt tgtatgttgg ataggtatgt tttttagttc tatagggatg
     6541 agccaaatag cacctatact tccattatat attaaacagt tgggggtaac tgatgttagt
     6601 ttaatacaac agtattcagg tataattttt ggatgtacct ttgtagtagc agcattcttt
     6661 tcgccaattt gagggaaagc tgctgataaa tatggaagaa aatcaatgct tttacgtgca
     6721 agtattggga tgggaatagt tatatttacc atggcgtttg ttcaaaatgt ttatcagtta
     6781 ttaggattaa gaatacttca aggagttttt acgggttatg ctactgcatg tactactctt
     6841 attgcaacac agacagataa aaatcattca ggatgggctt tgggtactct tgcaactgca
     6901 tcaactactg gctcattaat tggtccaaca gtaggaggat atatagaatc aatcttgggt
     6961 cttaaaagta catttattat aacaggagga ttgttgtttg tatcatttat catctctatt
     7021 ttatttgtag tagataattt taaacctaaa gaaataaaag aatcaatttc tatacctaaa
     7081 gaacaattaa atatattgcc aaataaattt ttaattgcat ctatttttgt aaccacattc
     7141 attactcaac tagctttata ctctatagaa ccaattgtaa ccatatatat atcacaactt
     7201 acaaattttg catcaaatgt agctttaata gctggattga cattttctgc atcaggatta
     7261 gcaaatttat tagcagctca aaaacttgga aaaatgtcag ataaaatagg tcctcaaaaa
     7321 gtattgttaa tttcactttt atgggctggg attatattta taccacaagc ttttgtaaaa
     7381 actgcatggc aactgatgtt gttgagattt ttattagggt tgtcagttgc agggcttaat
     7441 ccttctgtta acagcttgct taaaaaaatt gcaccagaag aatatgtggg aaaaatattt
     7501 ggatataatg catctgccca gtatataggt tgttcatcag gagcattttt agggggacaa
     7561 atatcagcac atttaggtat tagaacagta tttttttcaa caagtttatt gttgtttatg
     7621 aatgcacttt ggatgtataa atttactgga ttgtttatta aagataagac taaataatca
     7681 tactatttac atttctaatt ttatgatgta aaataaatat tttttatgta atttatcata
     7741 gaattatata aaaaataact ctatggtaaa aattggaaaa tattattatc gacaaaatct
     7801 ttgacttaaa aactatattg cgatagtatt aatttaataa aagtttgaga ggggcgtaag
     7861 gttatgacaa tttcaaaaat accacaagca gaattaaaag ttatgaagtt tatttgggaa
     7921 aaaaatgata cagtaacatc aaaagaaact attgaagcta tggaacgaaa atatggttgg
     7981 aaacaaacaa ctacattgac acttttatca agacttgtta aaaaacattt tttaagtgca
     8041 gaaaaaatag atagatacac tcattataca atagttgttg gacataagga gtatttaagt
     8101 gttgagacaa aagatttttt aagcaatata cacgacaatt ctttacagag tttaatttca
     8161 gcactacatg atgatgaagt tgttgataaa gatatgttgg atttatttga aagtcatttt
     8221 aaaaatttag aagaagagta attatatcag gataaaactc taagaattta attaatctat
     8281 ggctgaaaac cataaatggt attatttaat cagctactca ctattcataa agtaatatta
     8341 aataggttct ctaattagta aaatacctaa aataattgga atagggagta tcaagttaaa
     8401 tgataccact tatttaaata agaaatgatt tttaaaattt aaaataattt tataacttgt
     8461 caatattcat taatctaaag tattatttct at
//
LOCUS       DAMJWO010000117         8155 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.122, whole genome shotgun sequence.
ACCESSION   DAMJWO010000117 DAMJWO010000000
VERSION     DAMJWO010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8155
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.122"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..597
                     /locus_tag="PC366_003368"
     CDS             <1..597
                     /locus_tag="PC366_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2578851.1"
                     /translation="GLIKESSGQVLLNKHNLSNLAEHRRTQIVSRVFQDPSLGTCPSM
                     TVRENLSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLDLKKYLDVQVKFLSGGQRQS
                     LSLIMSCLTSPSVLLLDEHTAALDPKTSNEVIELTNKIVREKNITTLMVTHNLKHALH
                     YGDRLIMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
     gene            728..1750
                     /locus_tag="PC366_003369"
     CDS             728..1750
                     /locus_tag="PC366_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2578852.1"
                     /translation="MINKKRLASLILAGALSISMLTGCSQGGDSGNSKQESNSKGKEV
                     KKIGITQLVEHPALDATRIGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILITAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNENISY
                     VKTKQE"
     gene            complement(1914..2471)
                     /locus_tag="PC366_003370"
     CDS             complement(1914..2471)
                     /locus_tag="PC366_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDF2578853.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEDEYEK
                     REDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APNVQIYTAYHPIDAQLRNSGIEYGSPVKIGDNVWIGGGVIITPGITIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(2477..3553)
                     /locus_tag="PC366_003371"
     CDS             complement(2477..3553)
                     /locus_tag="PC366_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HDF2578854.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISKLNRLDKNTIYATDWGCELTLNREIGDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIVENPFTYTIYVRKTDLSNECVPIQIELEKSKMRFKK
                     GDRIYLDFPQEYLFCFRYNYNKKE"
     gene            complement(3554..4237)
                     /gene="modB"
                     /locus_tag="PC366_003372"
     CDS             complement(3554..4237)
                     /gene="modB"
                     /locus_tag="PC366_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HDF2578855.1"
                     /translation="MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(4386..5198)
                     /gene="modA"
                     /locus_tag="PC366_003373"
     CDS             complement(4386..5198)
                     /gene="modA"
                     /locus_tag="PC366_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2578856.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNEDKTDDGKQEKTTKSSDSVE
                     LNISAAASLKEAMAKIEEEYKKVDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSSVSGMKDLTTDKVKKIAVGEVESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSESGQKIFEEFGYKKVE"
     gene            5391..6320
                     /locus_tag="PC366_003374"
     CDS             5391..6320
                     /locus_tag="PC366_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2578857.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     TKDVEEYINSQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEITTWEDLTKPSITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGLGGYDLTDTGKTIAKV"
     gene            complement(6481..6930)
                     /locus_tag="PC366_003375"
     CDS             complement(6481..6930)
                     /locus_tag="PC366_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578858.1"
                     /translation="MKNKNNKDKNMLNIKVLRVLGVLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGTDCIVFLLFIVECVYLVGRYILKVKINWSEIIENEKGNFINNLLVEKI
                     QEESNIVYNLLNSYVLPHIYKKARVLMFKTYHMLIYIKEKYYYVNIY"
     gene            complement(7133..8113)
                     /locus_tag="PC366_003376"
     CDS             complement(7133..8113)
                     /locus_tag="PC366_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2578859.1"
                     /translation="MKNSFKNCISLRNKFIIISIVFLLILLIVSYIFGKLVYNSSVGL
                     EQLIKNEDIVKIFSERKDKPLEKLKNYKTSELMIQSSNNYKLESLFITSNIKTRDTMI
                     LVHGIGSSYYEMLKVAYRYLDKGYNVLVYNQRNTGNSGGDNYTFGLYERYDLDSLVKF
                     VKNKFPEGRLGVHGFSMGAGTAAMHSEINSKDDKVDFYILDSPYSEMKDAIRMGVLEK
                     RIPDILINYVVICGDLYNKFKSGFWYSDVKPYESVEKSNVPILFIHGTKDTVCNYQNS
                     KKMYDLVKHDKKDLWLIEGIGHVDGFEHDSTVYFNKIFKFIDSNVLSDKS"
BASE COUNT         2822 a         1340 c          982 g         3011 t
ORIGIN      
        1 gggcttataa aagaatcttc tggtcaagta ttattaaata aacataactt gtctaattta
       61 gctgaacaca gaagaactca aatagtaagt agagtttttc aagacccaag tcttggaact
      121 tgcccttcta tgactgttag agaaaacttg tctttagctc ttaacaaagg aaaactatta
      181 aatctaagaa aatgtcttcg ttacaaaaga gatttcttag aaaatttatt ggaaggtgta
      241 tctcttgatt taaaaaaata ccttgatgtt caagtaaaat ttttatcagg aggtcaaaga
      301 caatcattat cactaattat gtcgtgctta acaagtccat cagttttatt acttgatgaa
      361 catacagcag cacttgaccc aaaaacatca aatgaagtaa ttgaattgac taataagatt
      421 gtaagggaaa aaaatataac tacacttatg gttactcaca acttaaaaca cgctcttcat
      481 tatggtgata gattgataat gcttcataag ggtgaagttg tattagatgt aaaaggtaaa
      541 gaaaaagaac aattaacagt tgaagaaatc ttagaaaaat ttgaatatgc agtttaaaat
      601 aatatatcta ttgtattaaa ctcggcttta aaataaagtt aaaattacaa taattatggt
      661 tactttgtaa taattcatat gaatatatga acatatataa taataaattt ttgaggggga
      721 tataaaaatg attaataaaa aaagattggc aagtttgatt ttagctggtg ctcttagtat
      781 atctatgctt acagggtgtt cacaaggagg agactctggt aattcaaaac aagaaagtaa
      841 ttctaaaggt aaagaagtta aaaaaattgg tataactcaa ctggttgaac atccagcatt
      901 agatgccact aggataggtt ttgtaaaagc attagaaaag aacggattta aagatggaga
      961 aaatattgat atagacttcc aaaatgctca aaatgacatg cctactacac aaagtattgc
     1021 gagtaaattt gcatctgata agaaggactt aatatttgct atatctactc catcagctca
     1081 ggcagcattt aatgctacta aagatatacc tatacttatt actgctgtga gtgaccctgt
     1141 tgctgctgga ttagttaaaa ctcttgaaaa gccaggcaca aatgtatctg gaacatcaga
     1201 ttttgtttct gtagacaaag gtttagaact tcttaaaata tttgctccta aggcaaaaac
     1261 tataggagtt atgtacaata ctagtgaagt aaattccaaa gttcaagttg atgctttaaa
     1321 agaatatgca tctaaaaatg gatttaaagt tgttgaaaaa ggtataacta cttcaaatga
     1381 agttaaccaa ggtatttcta gtttagttgg caaaatagac gtattatatg ttcctacaga
     1441 taacttagtg gcttcttcta tgcctatagt ctctaaaata gctactgaga ataaaatacc
     1501 tgttatagca gctgaatctg ggccagttga aaaaggtgct cttgcttgtc aaggtatcaa
     1561 ctacgaaaaa ctaggttaca aaacaggtga aatggcagtt aaaattttaa atggcgaatc
     1621 agtatctgat atgcctgtgg ctacatcaga tgatacagat atcattgtta atgaagatat
     1681 attaaaagct ttaggtatgg aaaaaccttc taatgaaaat atttcttatg taaagactaa
     1741 acaagaatag aaagatattt tctatatacg attaatatgc ctgtttctat aaattaattt
     1801 atagaaacag gcatatattt ttattttaat gtattatcta tttaaagatt atatgtaaat
     1861 gctcttaata tgattgtata aattttactt gtataaactt tatacaatca tatttattct
     1921 tctattttct ttattactct acatggattt ccaacagcta cagtatttgg tggtatatct
     1981 tttgtgacta cacttcctgc acctattact acattatcac ctatagtaat tcctggtgtt
     2041 atgattactc ccccacctat ccatacatta tcacctattt ttacaggaga accatactct
     2101 atgcctgaat ttctaagttg tgcatcaatt ggatgatagg ctgtatagat ttgaacgttt
     2161 ggagctaaca ttacattgtc acctatttca attttacata catctaaaaa aatacaatca
     2221 taatttgcaa agaaattttc gcctacatgt atgttatatc cataatcaca cctaatgttt
     2281 tgttctacat ttatttgctt gccaactgaa ccaaatagtt gtcttaaaat atcttctctt
     2341 ttttcatatt catcctctaa agtattatta aacaatctag ttaatttttt acaatactct
     2401 ctttctttta ctaacaattc atcatttgca tagtatcctt ttccagacaa cattttttct
     2461 ttttcagtca tatagtttac tcctttttgt tataattgta tctaaagcaa aataaatatt
     2521 cctgtggaaa atctaaatat attctgtcac ctttcttaaa tctcatttta cttttttcca
     2581 attctatttg aataggtaca cattcgttag ataaatcagt ttttctaaca tatatagtat
     2641 atgtaaaagg attttctaca atgttaatca attcgaaaca taacttttca tttaaatctt
     2701 cattagaatc caagacctta atatgatgct ccctgattcc cacatattct atattatcac
     2761 ctatttctct atttaatgtc aactcgcatc cccagtctgt agcataaata gtatttttat
     2821 ccagtctatt taatttggat atatttttac accctgttat cttagcttct ataaggtact
     2881 ttggagattc aaagagctct tttttaggtc tctttggaag accttctcct ttgttgtaca
     2941 ctataatatc atcacaaact cggtaagctt cttcaatatc atgagtaaca aatagtatat
     3001 ctcccttgta atcttttaac atattcataa gttctttttc catattactt cttaaatgat
     3061 ggtccagtgc tgagaaaggt tcatctaaaa gtaatatatc tggagatgtt gccaatgctc
     3121 tagctagtgc taccctttgt tgttgaccac cagataattg ccaaggatat ctcccttcaa
     3181 acccatttaa tttaagtata tctaagtacc ttgctactat ttcctttttt tcactcttac
     3241 ttagttttaa aagcccaagt tctatatttt gacttacagt catatgtgga aacaaagcat
     3301 agttttgaaa taaaaatcct acctttctat cttgtgttga taaatttatc ttcttttcag
     3361 aatcaaatag aactctatca tttaatacaa ttttacctct tgttggtttc tcaagccctg
     3421 ctatacattt taatgtcata ctttttccag aaccagattc ccccaaaaac cccagagtac
     3481 ctttttcttg tttaatttct acctttagtt taaaagagga taaatctttt tcaatatcca
     3541 cgtataagct caactatcca cacctctttc ctataatttt ttgctgaaat tccgaccaat
     3601 aatttagtaa taaaatcatt gctatagata ttgctacaat aatcataacc cacatcatag
     3661 ctttattcat atctccgcct tcaacagcaa aaaatatagc tattggcata gtttgagttt
     3721 ttccaggtat atttccagct atcataagtg tagcaccaaa ttcgccaaga gctctggcaa
     3781 acgacagcac caatccacca attattccag gccatgctaa tggaactgca atcttaaaaa
     3841 atactttcca ttcattaaga cctaatgttc tagcagctga cagcatatta ttatcaatct
     3901 gttcaaaagc tgaccttgaa gttctataca tcataggaaa agacaccact actgctgaaa
     3961 ttacagttgc tgtccaacta aatattaaag tcctatcgaa atttaataaa aactttccta
     4021 taaatccatt cttcccacat agtaataata aaaagaaacc tacaactgtt ggtggcaaaa
     4081 ttagtggaag tgtaaatagt ccatctataa gacccttcca cttacctcta tagttagcca
     4141 taatatatga cacaaatatt cctattacaa aagttattat tgttgacaaa atagatgtct
     4201 taagtgatat ccataagggt gaccaatctg ttcccatctt tccctcctta attttaaatg
     4261 gaaatagtga aactaataac tctattaatt tcactatttc cattttatta taatacacaa
     4321 ttattttcaa ttttcattta tttatatata atttatactt aattacacat aatttattta
     4381 taagtttatt ctactttttt atatccaaat tcttcaaaaa tcttttgtcc tgactcactt
     4441 aataaaaatt cttcaaattt cttagcagca tctacgtttt tactagcttt aattactgaa
     4501 actggatatg taataggtga atgagttttt tcgtctgttt tttcaactac ttttatctta
     4561 tcattattga cagtatcact gaagtaaacg aatccaacat cagcatttcc tgattgcacc
     4621 catgctaaaa cttcttttac atcttttgca aatactagct tatcttttaa cttatctttt
     4681 aaatttaaat tagttaacac ctcatctgca tacttaccag ctggaacact ttcaacttca
     4741 ccaacagcaa ttttcttcac tttatctgta gtcaaatctt tcatacctga tacactactg
     4801 tcagcagaag aaataagaac taaatcattt tttactaaat ctttcatagt atcagaaact
     4861 aataacttct cttcatccaa agctttcatt tgtttttgac ctgctgaaat aaataaatca
     4921 caaggtgctc cttgttctat ttgttgttgt aatgagcctg atgctccata gttaactgta
     4981 agttttacat ttgaatcaac ttttttatat tcttcttcaa tctttgccat tgcttctttt
     5041 aaacttgcag cagccgatat atttaactct actgaatcac tacttttagt tgttttttct
     5101 tgttttccat catctgtttt gtcttcatta ctattgcacc caactgtccc caaagttaaa
     5161 catgcaacta atcctaatat tcccaatatt tttttcataa caatctccct ttttgtaaat
     5221 ttgatacaca ttttaatatg ttttattatg ttttatcatg ttttgttata tatagtttaa
     5281 ttatatatac atgataataa attttcaagt aatttattta cactactttt aaatattttg
     5341 ctacattttc ctttttttaa tgttaaaata accttatatg gaggtggatt atggactcat
     5401 tatcatcttt gacacctgtc gaggtagctg aattattaaa gataacaaaa aatactgtat
     5461 atgaattaat caaaagaggt gaacttcctt cttataaagt agggaaaaaa ataagagttg
     5521 atactaaaga tgttgaagaa tatatcaaca gccaaaaaac tggtaaagta aaggatacac
     5581 atttcaacaa taaaaatata gatataaata ataatttcaa aattattatt tctggtcaag
     5641 atgtaatatt agacatttta gctaggtctg ttgaaaaaaa attggatgga ataagtacat
     5701 ttcgctctta tataggtagt tataatgctt tgtatgagtt atataatggc agagtttcta
     5761 tagcatcatc ccatctatgg gatttcgaaa cggatgaata taatagcact tttgttaaaa
     5821 agctattgcc aggaatacca tgtgtactta taaatctagc ttatagaatg caaggtttct
     5881 atgttgctaa aggaaatcct aaagagataa caacctggga ggatttaaca aaaccaagta
     5941 taaccattgt aaatagggaa aaaggttctg gaactagggt tttactagat ggtaaactta
     6001 gacttctaaa ctttaatggt aaacatataa aaggttatga taatgaagaa ttatcacatc
     6061 ttggagttgc aagtactgtt tctcgtggaa tagctgatgt tggtttggga aatgaaaaag
     6121 ctgctttaca agtaaataat atcgacttta ttcctcttca caaagagcgc tatgatttag
     6181 ttattaaaaa agaagactta caaaatccag tttaccaaac tataattaac ataataaact
     6241 ctcctgagtt taaagctgaa cttcaaggtc ttggcggata tgatttaact gatactggaa
     6301 aaactatagc aaaagtttaa gattaaaatc gcaatctatt ttataagatt tataattttt
     6361 cacaaaattt ataacttaaa cacgaaataa attgcgattt tagtgtctca aaaaatttat
     6421 gtctttcatt ttatcatcca atacaaaata taatataatt aattgtgcaa tcatattata
     6481 ttaatatata tttacataat agtatttttc tttaatgtag attaacatat gatatgtttt
     6541 aaacatcaac acccttgctt tcttatatat atgtggcaac acatatgagt ttaataaatt
     6601 atatacaatg ttgctttctt cttgtatttt ttcaaccaac aagttattta taaaattacc
     6661 tttctcattt tcaataatct cactccaatt tatcttaact tttaatatat atcttcccac
     6721 taggtataca cactctacaa taaataataa aaatacaata cagtcagtac ctgttgtctt
     6781 atataaatta cccgatacta atggctttgc gaagaaatta taaaaattca aagtatcacc
     6841 cgtataatca aaaagtatta atagcactcc tagaactctc aatactttaa tattcaacat
     6901 gtttttatct ttattatttt tgtttttcat atatactacc tctcttttct ttagatttga
     6961 ttgtaatcta atactaactc ttttatttga ggtataaatg aatttaattg gtagttattt
     7021 tcatttttac tagaaattaa ttcacattac taaacaaaac ttatatttaa acataaaaat
     7081 agcctatcta ttttttaata aatacaaaaa taaataagct actaatattc aattaacttt
     7141 tatcacttaa aacattacta tctataaatt taaatatttt attgaagtat actgtactat
     7201 catgttcaaa tccatcaaca tgaccaatac cttctataag ccataggtct tttttatcat
     7261 gtttaactaa atcatacatt ttcttgctat tttgataatt acaaacagta tcttttgttc
     7321 catgtataaa cagtatgggt acattagatt tctcaactga ctcatatggt tttacatcac
     7381 tgtaccaaaa tccagattta aacttattat ataaatctcc acaaatcacc acataattga
     7441 ttaatatatc tggtattcgt ttttctagta ctcccattct aattgcatct ttcatttcag
     7501 aataaggaga atccagtata taaaaatcga ccttatcatc ttttgaattt atctctgaat
     7561 gcatagcagc tgtccctgct cccatggaaa atccatgcac tcctaatctt ccttcaggaa
     7621 atttattttt tacaaattta actagactat ctaaatcata cctttcataa agaccaaatg
     7681 tgtaattatc tccaccacta ttaccagtat ttctttgatt ataaactaat acattataac
     7741 ctttatctaa atatctatat gctaccttta acatttcata gtaactactt ccaattccat
     7801 gaacaagtat catagtatct cttgtcttta tatttgaagt tataaaaaga ctttcaagct
     7861 tgtaattatt agaactttgt atcattaatt cagatgtctt gtagtttttt aatttctcca
     7921 gtggtttatc ttttctctca gaaaatattt ttactatatc ttcgtttttt attaactgct
     7981 ctaaaccaac cgaactatta tacactaatt tgccaaatat ataagataca attaatagga
     8041 ttaatagaaa cacaattgat ataattataa atttatttct taaactaata caatttttaa
     8101 aactattttt catatttatt taccatacaa ttttcctata ttatattttc taagt
//
LOCUS       DAMJWO010000118         8031 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.123, whole genome shotgun sequence.
ACCESSION   DAMJWO010000118 DAMJWO010000000
VERSION     DAMJWO010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8031
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.123"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            89..424
                     /locus_tag="PC366_003377"
     CDS             89..424
                     /locus_tag="PC366_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2578860.1"
                     /translation="MYNIDDMIYNCPVEALSNILGKKWVAIIIWKIQEDKKRFGELQR
                     AIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNVVESTYFLSESGLRLLPVMEKMIMWS
                     NKNLNCDKY"
     gene            561..1838
                     /locus_tag="PC366_003378"
     CDS             561..1838
                     /locus_tag="PC366_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HDF2578861.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMKAITAFILGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIKSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNTSQNSKIESKQEENKRENSTDKEENSDGNNSQKDSNNDNNDNG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPYIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKDQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            1959..3347
                     /locus_tag="PC366_003379"
     CDS             1959..3347
                     /locus_tag="PC366_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDF2578862.1"
                     /translation="MKKTFDAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTC
                     VNVACIPTKSLENSANSVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENEIYELVADNIFINTGSRPFIPNIKGIENKNIVYD
                     SESLMNLRVLPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEI
                     IKLLAKRNVKIVNNANIKEIKEVSESAIVEYEVDGKSKELTSNMILVATGRKANTEGL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGD
                     KTRTTNDRKNIPNSIFISPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKAD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPNMIKEV"
     gene            3718..4431
                     /locus_tag="PC366_003380"
     CDS             3718..4431
                     /locus_tag="PC366_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017208807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HDF2578863.1"
                     /translation="MNKISKRGFDDSDKRWFSSKELTRLIKAKEEIEWLLNRDYKIDP
                     VVTFVGDRYQFSIRQRDALKRAVCTDEKNIIRQSKRLFLDKIKEDTVNIDGFNLIISI
                     EVALSGGTLVIGSDGNIRDLAGLRGTYKIIDKTEEALNLIGKFFNKYNAQNLKFYLDA
                     PVSNSGNLKYRILEHAKTWGIETEVELVKNADVVLEKLDRVVSSDAVIVDKCISYFNV
                     ARGIIEEYIKECNIINLNK"
     gene            4549..5418
                     /locus_tag="PC366_003381"
     CDS             4549..5418
                     /locus_tag="PC366_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF2578864.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANVNLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKDLVSVSEYAWSNLNLREDKSITSNIITV
                     IPEKSRVEVLQVDGDWSKIVYDDKIGYVFNYFLSTDGNKPNELDYKYFYTDMIKFVNE
                     NNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRK
                     PSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(5573..6718)
                     /locus_tag="PC366_003382"
     CDS             complement(5573..6718)
                     /locus_tag="PC366_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDF2578865.1"
                     /translation="MSTYYVPPINLLGKGCLNEAKDSIKSLGTKKAFVVSDKFLVSNG
                     TVKKVTDILSQIDVDFVVYDEVKQNPTVTNVDKGLKILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIVAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDTNSLATMTVNDPELMISKPSNLTAATGMDALTHAVEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSAPAKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENSMKDACAGANPVFFDKEKIIELFMKIS"
     gene            complement(7051..7827)
                     /locus_tag="PC366_003383"
     CDS             complement(7051..7827)
                     /locus_tag="PC366_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDF2578866.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
                     GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
BASE COUNT         3101 a          919 c         1308 g         2703 t
ORIGIN      
        1 aataaagcta ggtatattta taatattaat aaatatattg ctataaaagt ttgtttaata
       61 aattaaataa agaaaagagg agaataaaat gtacaacata gatgatatga tatataattg
      121 tccagtagaa gctttatcaa atattttagg taaaaaatgg gtggctataa ttatatggaa
      181 aatacaagaa gataagaaac gatttggaga gctacaaaga gctataccag actgtagtaa
      241 gaaaatgtta gttcaacaac tagatttttt aattgaacag gggattatag tcaaccaaaa
      301 aaagttggtt aataatgttg tagagtcaac atatttttta agtgaatcag gattacgatt
      361 gcttcctgtc atggaaaaaa tgattatgtg gagcaataaa aatttaaatt gtgataaata
      421 ctaaaattta ctctgtaagt aatgaaaatt taattaagct atgagtagaa aaatgtatta
      481 aaattacata attttttagt tagattttaa tttagaaatg ggattgtaat attggaaata
      541 aaataaggag gaattttaat ttgcaaaatg taaatttatt tttagtattt atagaaggta
      601 tagtatcatt cttttcacca tgtatactgc caattttgcc tatttatttg agtatattgt
      661 caaatagtag tgtagaaaat ctaaaagaag gaaagacgag ttttatagga agttctttat
      721 ttaaaaatac tatatttttt gctcttggaa tctcaacaac attctttata ttgggttcat
      781 cagtaaaagt attgagtatg ttttttaatg aaaataaaga tttaataatg tttattggtg
      841 ggattataat tattatcatg ggattatttt acatgggaat aattaaatct tcaatattga
      901 atagagaaaa aagatttaat gttaagttta aagaaatgaa agcaataaca gcttttatat
      961 taggttttac gtttagtttt ggatggacac cttgtattgg tccaatattg gcatctgtat
     1021 tagtcatggt ttcaagttca agtaatcatc ttagtgccaa tcttttaata gcagtatata
     1081 ctattggttt tattttgcca tttataatta cagctatgtt ttacagtaaa ctatttaaaa
     1141 ctatagataa gataaaatct aacatggaaa ttattaaaaa aataggtggg attatactta
     1201 tagtatcagg aatattaatg atggtaaatg gatttggaag tataagcaaa cactttaata
     1261 cgtcacaaaa tagcaaaatt gaaagcaagc aagaagaaaa taagcgagaa aattctactg
     1321 ataaagaaga aaattctgat ggtaataata gtcaaaaaga ctctaataat gacaataatg
     1381 ataacgggtc taatgatgaa gatagaataa agtctattga ttttacttta acagaccagt
     1441 atggtaaaac acataaatta agtgattatg aaggcaaagt tgtattctta aatttctggg
     1501 ctacatggtg tcctccatgt aaagaagaaa tgccttatat agaacaactg tataaagact
     1561 ataataaaaa caatgatgat gtagtaattt taggagtagc ttcacctaat ttaggtagag
     1621 aaggttcaag ggaacatgta gttaacttct taaaagacca aggttataca ttccctgttg
     1681 tacttgatga agatggagca ttagcatatc aatatggaat taatgctttt ccaactacat
     1741 ttataattga caaggaagga tatgtaactc agtatattcc aggagctatg gataaggcaa
     1801 ctatggcatc atttattgaa aatcagagaa ataaataaaa gtatttaagt atatgtttat
     1861 gaatcaattt aaggttacaa aaaagtgcct aattgtacca cctaaataat cttgttatag
     1921 taaaagtata aacaatacaa gaaagggttg aattttatat gaaaaaaaca tttgatgcta
     1981 taataatagg atttggaaaa ggtggaaaaa cattagcagg agatttggca aacaggggat
     2041 taaaagtagc tttaatagaa aagtcaaaca agatgtatgg tgggacatgt gtaaatgtgg
     2101 catgtatacc aacaaaaagc ttagaaaatt cagcaaacag cgtaaaaaca aagaatataa
     2161 attcttggga tgaagtacaa gctgaatatg agaaagctat agataaaaaa gaaactttaa
     2221 ttacaaaact cagagaagct aactataata aattaaattc aaatgagaat gtaactatat
     2281 tcacaggaat gggaactttc attgatgaaa aaacagttca agttaaaact gaaaatgaaa
     2341 tttatgagtt agtagcagat aatatattta ttaatactgg ttcaagacca tttataccta
     2401 atattaaggg aattgaaaat aagaatatag tatatgatag tgagtctctt atgaatctaa
     2461 gagttttacc taaaaaaatg acaattatag gagctggatt tataggttta gagtttgctg
     2521 gtatttatag ttcatttgga gcagaagtta caatattaaa ctctaataat ggcattttac
     2581 caaatgaaga tgttgaggat tcagaagaaa taataaaatt acttgcaaag agaaatgtaa
     2641 aaattgttaa taatgcaaat ataaaagaga ttaaagaagt ttctgaatca gcaatagtag
     2701 aatatgaagt agatggtaaa tctaaagaat taacaagtaa tatgatactt gtagctacag
     2761 gaagaaaagc aaacactgaa gggctagggc tagaaaatgc aggtatagaa ttaaatgaaa
     2821 gaggatttat taaagtctca gaaactctta agactaataa agagcatata tgggctatag
     2881 gagatataaa tggaggtcca caatttactt atatatcatt ggatgattat cgcatagtta
     2941 ttaatcagtt atttggagat aagactagaa caactaatga tagaaagaat atcccaaatt
     3001 ctatatttat aagtccagca ttttcaagag ttggtcttaa tgttaaacaa gctaaagaaa
     3061 agggatatga agtattagtg gcaaagatgc cagtagaagc aattccaaga gctaaacaga
     3121 ttggcaaggc agatgggttt ataaaaatag tgatagataa aaaatccaat aagatacttg
     3181 gagctagtat gatatgtgaa aattcaagtg agattatcca tcttattcaa ttagctgtag
     3241 atttagaagt agagtataca tatttaagag accgtgttta tgcacatcca actatgacag
     3301 aagctcttaa tgatattcta tctcctaata tgataaaaga agtataacat aagtttaata
     3361 tataaaccta aaattatcat tataagtaga ttttagaaag aggctatctc aaaaaataga
     3421 gataagtctc ttttttactt tttaaatgat aaaaatatat ttgattttat aaaagaagat
     3481 tatcttatga actaaaaagt ttattttaaa acactaccta tttatgttat aaacttataa
     3541 atataatata gaatctatta ttctgtatta ttaagtgagg ttaagcgtta taattaatta
     3601 taaatattga ataatctaaa tggataagat aatggtatta aaaattatct taaaaggtga
     3661 aataatctgt atttaatgta gtacagttat atctttaaag caaggtggtg aaatgatata
     3721 aataagatat ctaaaagagg gtttgatgat agtgataaaa gatggttttc aagtaaagaa
     3781 ttaacaagac ttataaaggc taaagaagaa atagaatggt tattaaatag ggattacaaa
     3841 atagacccag tcgttacttt tgttggtgat agatatcagt tttctataag acaaagagat
     3901 gcattaaaaa gagcagtctg tactgatgaa aaaaatatta taagacaatc aaaaaggctt
     3961 tttctagata aaatcaaaga agataccgta aatatagatg gctttaattt gataatatcc
     4021 atagaggtag cattatctgg tggtactcta gtaataggaa gtgatggaaa tataagagat
     4081 ttagcaggtc ttaggggaac ctataagatt atagataaaa cagaagaagc tttgaatctg
     4141 ataggtaaat tttttaataa atacaatgca cagaatctta aattttattt agatgctcca
     4201 gtttctaatt caggaaattt aaagtatagg atattagagc atgccaaaac ttggggaatt
     4261 gaaactgaag tagaattagt aaaaaatgca gatgttgtat tggaaaaatt agatagagta
     4321 gttagtagtg atgcagtcat agttgacaag tgtataagtt attttaatgt ggctagaggt
     4381 ataattgaag agtatattaa agaatgtaat atcataaatt taaataaata gataaataga
     4441 ggtgagaata tataagtata tgtagcaata ttattagtaa tacaagtaaa gtttgaaaat
     4501 aggagaacga atacatatcg aatttcataa aatgttgtaa aaagacatat gagaggatgg
     4561 atatgtgtga aattaactaa actaaatatt aaaaaatata gagcacctat atataaatat
     4621 gctttagcaa atgtaaattt gaggtctgct aaatctacta attcaagtat cataacagta
     4681 atacctcagg gagctaaaat ggaagtattg gatgaagaag atgactggat taaggtgatg
     4741 tacaattctc aagaaggata tgtgtataag gatttggtat cagtaagcga atatgcttgg
     4801 agtaacttaa acttaagaga agataaatct ataacttcca atataattac agtaattcct
     4861 gaaaaatcta gggttgaagt ccttcaagta gatggagatt ggagtaagat tgtatatgat
     4921 gataaaatag gatatgtttt taattatttt ttatcaactg atgggaataa accaaatgaa
     4981 ttagattata agtattttta tactgacatg attaaatttg ttaacgaaaa taatattaaa
     5041 agtactagcg attatctaat tgtaacagac cttagaaata aatatactta tatttttaag
     5101 aaagataatg gaggctgggg gcaactttac aagtggcaat gtactatagg caagcctgag
     5161 actccaacta taacaggtat attttatata agtggaagaa aaccttcttt tggaacggat
     5221 gagtattcag ttaagtatgc tactagaatt aaaggtggat attactatca ttctgtgcta
     5281 tatgattcaa caggaagtta tataatagat ggcagacttg gtgaagctct tagtcatgga
     5341 tgtataagat taagtacgga aaatgcaaag tggatatatg ataatatacc agatacaaca
     5401 acagttataa ttcattaaga aaaattttga gtttttattg ggataatgat tctcaaatta
     5461 ataggattat atattaactt cttcataaag agtactattt aaaaagtgta ataagagagt
     5521 gctattaaca aaacaaagat attttgaggc actctcttat aaatatacat aattaagata
     5581 ttttcataaa caattctata atcttctcct tatcaaagaa aacaggatta gcaccagcac
     5641 aagcatcttt catagagttt tctgcaagca attcaaaatt aggattatca acacctacat
     5701 cttttaaaga ttttgggatt ccaacctctt cagaaagagc ttttatctta tctattacaa
     5761 agtcaacaca ctctttatct gatttattat ttacatccat tccaataact tcagctattg
     5821 gtcggaattt ggcaggggct gatttagcat tttcctcctc aactattgga agtagcatgg
     5881 cattacatac tccatgaggt aaatcatata aacctcctaa ttgatgagcc atagcatgta
     5941 catttccaag acctgcatta ctaaaggcaa ttccatttaa aaaacaagca taacacattt
     6001 gttctctagc ttctatgtca ttaccatttt taacagctct tggaaggtat ttaaatatct
     6061 gctttatagc atataaggca gttgaatctg taacatcata agcaccatta gctactacag
     6121 cttctacagc atgagttagt gcatccatac cagttgctgc tgttaaatta gatggtttgc
     6181 taatcattaa ttctgggtca tttactgtca ttgtagctag tgagttggta tcaaccatta
     6241 tcatctttac atgtctgtct tcatcagtta taacatagtt tattgtaact tcagcagatg
     6301 taccagcagt agtagttata gctacgatag gaagacattt tttagaagtt ttgttgatac
     6361 cttcatagtc tctaatatct cctccattag tagctaatat agagatagct ttaccacagt
     6421 cttgtggaga acctcctcct atagttataa cgaagtcaca attttctgat tttaatattt
     6481 taagtccttt atccacatta gttacggttg gattttgttt aacttcatca taaacaacaa
     6541 agtctacatc tatctgagat aaaatatctg ttactttttt tacagtacca tttgaaacta
     6601 gaaatttatc actaacaaca aatgcttttt tagttcctaa tgatttaatt gaatctttag
     6661 cttcattaag acatcctttc ccaagtaaat ttattggtgg tacataataa gtgctcataa
     6721 ctaaaatctc cttttatttt cattgatttt tatgtaaaaa tatatatcta acaattttca
     6781 ctaatttact cataatatat cgtatcttag attgagatag ggttactggt tcttatataa
     6841 gaacttaatt cgtaattacg attatgatta gaatttaaca tagtattttt atcatgtcaa
     6901 taaaaatata aaaaatatta taaaaaaaac aaagttactg tagttaaatc agcaactttg
     6961 tttttatagt ataaatcaaa taaatacatt agtttaaaac aaaattttta attattatgt
     7021 tttgatatct tccatataca gaatattaat ctaatttatt acaatgtctt cattacgttc
     7081 ttccatcatt gattgaatat ttttctgagc atttaagagt aattttttta tcagttctat
     7141 tttttcgtca ttagctctaa ataaaggcag tgttacacta acagcagctc ttatacatcc
     7201 attttttctt attggtacgg caagacattt taggtgttcc attgattctt cacactctga
     7261 agctatttgt gttctttgaa cttcaagaag ctggtcgtat aaaacatcaa aatctgtaat
     7321 tgatttttct gtaaaacctt ttagaccatc tggatataag cttattagtt tttccttgtc
     7381 aaaatcacat aaaagagctt ttccaagacc tgtacaatta gcaggtattt tttttccaac
     7441 ataagaaata agtctaattg gttctggaga atctactttt ccaatataaa gaacttcatt
     7501 attgtcaagt ataccaagct gacaagtttc agaacaggaa ttaactatat tagtcatttc
     7561 gtcaattata tagttaaaaa tagttctttt ttcaaaaaat gaagacccta atgtgtaaga
     7621 acgtatccct atagaatatt tggatgtgtt tttatcaata gtaatgtatt ttctagcatt
     7681 aagtgtatga actataggaa agatgctact ttttggagca ttgataacat ctgctatttc
     7741 tgtaagagta tatccatttt cggattctgc taatgcttct aaaatatcta atatcctagc
     7801 tgttgggcga tgattatctg aagtcataaa tttccccctc tttttattaa tttaaagtat
     7861 tagaatatgt tgattttagc acactatacg atattttaca atgtagaaaa taaatatgta
     7921 aatttatata taaataagct cttgatttag atacagatag atattttttt agactgtaca
     7981 ttaaggaata actaatttcc aaaatatacc taaagaaagt aagtgatatt t
//
LOCUS       DAMJWO010000119         7921 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.124, whole genome shotgun sequence.
ACCESSION   DAMJWO010000119 DAMJWO010000000
VERSION     DAMJWO010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7921
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.124"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     misc_binding    109..320
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            483..1772
                     /locus_tag="PC366_003384"
     CDS             483..1772
                     /locus_tag="PC366_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HDF2578867.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGISVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIIATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSTKNKQEIDKAV"
     gene            1826..2905
                     /locus_tag="PC366_003385"
     CDS             1826..2905
                     /locus_tag="PC366_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HDF2578868.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     NKSDSKGAVENILKELCGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            2926..4470
                     /locus_tag="PC366_003386"
     CDS             2926..4470
                     /locus_tag="PC366_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020246462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HDF2578869.1"
                     /translation="MYRVGIDVGGTNTDACILDGELKVIHSVKVATTKDVETGVYNAL
                     KKVIDESKIDHSLIKYAMLGTTHCTNAIVERKRLNNVAMIRIGKPATTAILPFIDWPE
                     DLREKIELDSILVSGGYEFDGRKINELCKDEVVEFCNRIKGKVESVAISGVFAPVNKQ
                     QEEEVAKWVREILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALK
                     DLGIDAQIYFSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGG
                     TTSDLGVLYNGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPES
                     VGYRITEDAIIFGGDTLTLSDVVTKLDMAFEDRKSNVENLDKEYCNEVYKKVILKLED
                     AVDQMKTSQDDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVE
                     KVYSLDKMSREDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVK
                     VVGDLI"
     gene            complement(4633..5175)
                     /locus_tag="PC366_003387"
     CDS             complement(4633..5175)
                     /locus_tag="PC366_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HDF2578870.1"
                     /translation="MKSYIALLRGINISGKNKIIMSELKASFVELGYSEVSTYLNSGN
                     VVFLSDVDDNKVISNTIRLMIKKQFELEIPVFIISQEELKDILNNAPNWWGDNNKEIY
                     DNLIFMFPDLSYDEFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYKKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(5323..5607)
                     /locus_tag="PC366_003388"
     CDS             complement(5323..5607)
                     /locus_tag="PC366_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2578871.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYIL
                     VYRENEDKEKNEHDKNLNETINEFKKEEEKRMQAKSAARAIAEAKKRVLY"
     gene            complement(5670..6434)
                     /locus_tag="PC366_003389"
     CDS             complement(5670..6434)
                     /locus_tag="PC366_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HDF2578872.1"
                     /translation="MNNYLKFATYQLIGFTSSIPSLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSIAQASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMINTIENFRKSNKTFKEF"
     gene            complement(6716..6982)
                     /locus_tag="PC366_003390"
     CDS             complement(6716..6982)
                     /locus_tag="PC366_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF2578873.1"
                     /translation="MIESRCGILCYECGYKEKVNCKGCTDIEKPFWGEQCPVKSCCED
                     KNLIHCGLCDTFPCEMLNQFAYDKEQGDDGKRISQCKKWAVLAL"
     gene            complement(7025..7834)
                     /locus_tag="PC366_003391"
     CDS             complement(7025..7834)
                     /locus_tag="PC366_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2578874.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKEKL
                     TLIPDASGCMIFKFDKKGIESAFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIKELVEQLDMLFLSYLLKSNIVDMT
                     IPILENARKQNSIMSVKNISQISCYSERHLNRIFNNSLGMSVKSYLRLLRINLVLQEV
                     QNNKRPFATLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
BASE COUNT         2758 a         1004 c         1291 g         2868 t
ORIGIN      
        1 gaaaatttac atataaaact aaaaaatgta agtaattgac tttttaagtt gacaaaatat
       61 tgcatatata ttatgatata aatcataaat taactacaaa tcaatattat atattcgtag
      121 aagaagaaag tagcataaag gaattttaca gagagttaga tttggctgag aactaatatt
      181 ggaatttatg tgaaaaggac tttggagaat actattgtaa ttatgttaga atagtggttt
      241 aattcgcctt aagaaaatga gtgagtaaaa ttaattttta ctaataagag tggtaacacg
      301 gatttatatt cgtctcttgg atttttccaa gaggcgtttt ttattataaa cttatttcag
      361 aaaatttaaa actatatatt aaatgaaaat tataaaaata tgatagttaa taaatttata
      421 aattagaaaa ttgtaaaata tgctaaggtc agtagtttta cgatttaaat ggagggatga
      481 aaatggaaga agaaaaaatt aactatgctc tggaacagat tccagagaat caaaaacgtg
      541 gttgggtagc tatgttttca gttttagtag caataggtgt ggatttatca tctgttattt
      601 taggcgctga gttggcacag agtatgccaa tgaaacaagc aatattgtca gtaattgttg
      661 gttcattttt ttctgcaatt ttgtatacta catgctcttt ggttggttca tctacaagtt
      721 tatctacatc tatgataaca aagtatgtat ttggagaagc tggagcaaaa atattttctc
      781 tagttatagg ggtttctcta ttaggttggt ttggagttca agtaggtttc tttgcacaaa
      841 atgcacagat aataataaaa gatatattta atttagatgt cagtatgcag attttaagcc
      901 taataggtgg tctcttgatg atgagtactg caatttatgg atataaggcc atggagaagt
      961 tgagtgtgta ttcagtacca tttttattag ttcttatgat gctaactata ttcttagctt
     1021 ttagagcaaa tggaatttca gttgatgata atatgaaatc tactatgaca tttgcaggtg
     1081 gagtttctct gtcaatgagt ataataatag ttggtgcaat tgtatctcct gatataagtc
     1141 gttgggctaa aagtagaaga gactgtgctc tttcaagctt tttgggaata caatttggaa
     1201 atgcttttat gataatagtt tcgatagtat tagtaaaatg tatgggaact tcagatatta
     1261 tgagaatttt tattacatta ggaattgcta taccaggtat aatagtactt acattagcac
     1321 aatggactac aaatacaagt aatgtatatt cagcatcatt aagtatagct cttgtactta
     1381 agaaggctcc tgagaaagta ttaactatag tccttggtat tatagcaaca ttattggctg
     1441 tatttggaat atatgaaggt tttataggat ttttaaattt acttggaatt gtaattgcac
     1501 ctgttggtgg tgtatataca gcagaatatt acatagtaaa gcaagaactt aaaggctttg
     1561 ataaaggagt attatataaa ccaatagtta aacgttcaat agtgtcttgg ataattggta
     1621 tattaataac ttacctttca acatatggat ttataactct tactactata gcacctttag
     1681 atggttttat agcagggttt gtagtacaat ctattattgg aaaagtgctt tgttcaacaa
     1741 aaaataagca agaaatagac aaagcagtat aaagaaattt gtttataaag tataaaataa
     1801 attagaaata tgaggagaaa gtaacatgag atttttaaca gaagaaagtg tagataaaat
     1861 agcagttggt gcagcagtgc ttggaactgg aggtggaggt gacccatatg taggtaaatt
     1921 ggttgcaaaa caagccatta aaaagtatgg tcctgtaaaa gtaataagtt tagatgaact
     1981 tgatgatgat gctttggtag ttccagtatc tggtatgggt tctcctgtaa ttacaataga
     2041 aaaattactt tcagaagtag agttaactac ccctttagaa ataatggaga aattattaaa
     2101 tagaaaagtg gatgttataa ttcctataga aataggaggg ataaactcac ttatgcctat
     2161 agcagttgct gctaaaaaag gacttcctat cttagatgca gattctatgg gtagagcttt
     2221 ccctgaagct caaatggtaa ctttttatct tgaaggatat gaggcatctc ctgccgtaat
     2281 gtctgatgaa aaaggtaatt ctgccatcct ttatcctgtg gatggaattt ggtcagaaag
     2341 attagctaga actttaactg tagaaatggg aggaagttct tctattagtg actataattt
     2401 aagtggagct caagttaaaa aagctgctat aggtaatact cttacaatag ctgaaactat
     2461 aggagggttt ttacttgaaa ataaatctga ttcaaaaggt gctgttgaga atatactaaa
     2521 agaattgtgt ggatacaagt tatttgaagg aaaagtaatt gatattaaga gagagttgaa
     2581 aggtggattt actagaggac atgccttttt tgctgggatt aatgagtatg atggagagta
     2641 ttctatatta ttccaaaatg agaatttaat tgccaaaaaa ggtgatacac cactttgtat
     2701 tacaccagat ttaatagcag tattagattt agaaactgga tttccaataa ctacagagag
     2761 aataaaatat ggctctcgtg ttatggtagt agcttttcct tgtaatgaaa agtggagaac
     2821 agaaaaagga attgagacag ttggacctgg atactttgga tatgatgtgg aatataaaac
     2881 agtagaagaa ttacaaggaa aataaaagtt taggaggaaa ttttgatgta tcgtgtagga
     2941 attgacgttg gaggaacaaa tacagatgct tgtatactgg atggggaatt aaaagtaatt
     3001 cattcagtta aggtggcaac tacaaaagat gttgaaactg gtgtttacaa tgccttaaaa
     3061 aaagttatag atgaaagtaa gattgaccat tcattaataa aatatgctat gcttggtaca
     3121 actcattgta caaatgctat tgtagaaaga aaaagactta ataatgtagc tatgataaga
     3181 ataggaaagc cggccactac tgccattctt ccatttatag attggccaga agacttaaga
     3241 gaaaaaatag aattagattc aatattggta tctggtggat atgagtttga tggtagaaag
     3301 ataaatgaac tttgtaaaga tgaagttgta gagttttgca atagaataaa aggcaaagtg
     3361 gaaagtgttg caataagtgg agtatttgct ccagtaaata aacaacaaga agaagaagtt
     3421 gcaaaatggg ttagagaaat tttaggggat attcctatat ctttatcaaa tgaaataggt
     3481 aatataggta tattagaaag agaaaatgga gctattttaa attctgcatt gtctcaagta
     3541 ggtaaagctg tatctttagg atttgaaaaa gcacttaaag acttaggtat agatgctcaa
     3601 atatatttca gtcaaaatga tggaacatta atgaatttag agtatacaat gaaataccca
     3661 atttttacaa ttggatgtgg aataacaaat tctataagag gagcttcctt cttatcaaaa
     3721 gtaaaaaatg caatagtatt agatgttggt ggaactacaa gcgacttggg tgtactatat
     3781 aatggattcc ctagagaatc atctattcca gttacaattg gaggagtaca tacaaacttt
     3841 agaatgccag atgttttaac tattggtctt gctggtggta catgtgtaaa aggcgaaaaa
     3901 gataatataa agataggtcc tgaaagtgtg ggatatagaa taactgaaga tgcaataata
     3961 tttggtggag acactctaac tttatcagat gttgttacaa aattagatat ggcgtttgaa
     4021 gatagaaaaa gcaatgttga aaacttagat aaagagtatt gtaatgaggt atataagaag
     4081 gttattttaa aattagaaga tgctgtagac caaatgaaga ctagtcaaga tgatgttgaa
     4141 ttggttttaa ctggtggagg aagtataatt gttcctgaaa aactaaaagg cataagcaat
     4201 gttataagac ctcctcatta tactgctgca aatgctattg gtgcagcttt aggacaaata
     4261 agtggagatg tagaaaaagt atacagttta gataaaatgt cgagagaaga tgccatagaa
     4321 gatgcaaaaa aagaggctgt aaataaagct ctaaaagctg gtgctaaaga agatactata
     4381 gaagtattaa atatagaaga tgttccactt gcataccttc ctggtaatgc acttcttata
     4441 aaagtaaaag ttgttggtga tttaatttaa agaataaata taagtatttc cagaattata
     4501 taaatatttc tggactcatt tttaaactta ttttatcaat aaaaacagca taacttttga
     4561 ctatattctt ataagtttcc gaacagccga tatataccta ttttttgagg tttatcggct
     4621 gtttgttatc ttttatcgca ttccaactat ttttcttacc gtatttgctg tacgaattgt
     4681 aatcttatca cttacatttg aactggcagt ctttgaccac caatttgtct ttttataatc
     4741 tttacgacta aaagaccaaa agatagcatt tttataatga tatacttttt catactcttc
     4801 tttaggattt ccaacctcat cataaaactc gtcataagat aagtcaggaa acataaaaat
     4861 aagattatca tatatttctt tgttgttatc tccccaccaa ttaggagcat tatttagtat
     4921 atcttttaac tcctcttgtg aaataataaa aactggtatt tccaattcaa actgtttttt
     4981 tatcattaat cttattgtat ttgagataac cttgttgtca tctacatcac ttaaaaagac
     5041 aacattacca ctattaaggt atgtagaaac ttctgaataa ccaagttcta caaagcttgc
     5101 ttttaattca gacataatta tcttgttctt accacttata ttgatacctc ttaataatgc
     5161 gatataactt ttcatataat aagttcacct ctaaacattc acatttttct atgtagtaca
     5221 aactggaatt tgcatctttt ataattcttt caaaacttct tcatatgtaa tttttttaat
     5281 ataaaaaaat cggtgcttaa tttgtaccga tttttatttt tcttagtaaa gaactcgttt
     5341 ttttgcttct gctatagctc tagcagcact ttttgcttgc attctttttt cttcttcttt
     5401 tttaaattca tttattgttt catttagatt cttatcatgt tcattttttt ctttatcttc
     5461 gttttctctg tatactaata tataatctat tattgattcg tttattatct gagatatact
     5521 tttattttca ttaattccta ttctcttaac ttccttaagt agagtctcat caatatgaac
     5581 cgttgtttgc tttgtatttt ttgccacctt aatcacctct taaaaaaaat tctaacatta
     5641 aaattttttt tagtcaataa attttaatat taaaattctt taaatgtttt atttgatttt
     5701 ctaaaatttt ctattgtatt tatcatctta ttttttatat tttcacctag tacagaagac
     5761 tttagtctag gattttctat atggtcataa attggttcta aaaattcgac ttcgacagga
     5821 acagagttaa ttttaccaat aggttggtat ccttcataag tatcttttga attttttatt
     5881 acgagtggaa caatagggca ttttgcttta tatgctatct ttaaagctcc acttctaaac
     5941 tccgaaacca atgaatttgg ttctttaatc catgttaaat ctccttctgg aaacactgcc
     6001 atactttgac ctgtaagtat attttgagag gcttgggcta tactctttat accctcacga
     6061 ttgttttttc tgtttacata tacacatctt agtaattttg cccattcttt aaatataggt
     6121 atatttctcc aaactggttc atctgcaatt acacatccaa ttggtctttc tacacttgct
     6181 gttagtatga agctgtcaag catactagaa tgatttacaa caaatagaag tggttctttt
     6241 ggcagtgttt ccttaccaat tatattaagc tctatgttca ctatatctaa agatttttta
     6301 gcttgttttt gcataaattc aaatttttcc tttaagctaa atttatcagg attcttttta
     6361 attttaataa ggctaggtat agaagatgta aaacctataa gttgatatgt agcaaatttt
     6421 aagtaattat tcataaaatt atctccttaa aataaaatta tttattactg taaagatttt
     6481 aacataaaat aaaatttaag tctattttaa ttcaattttg taacatatat tttaaataga
     6541 cagagattga gattttatat ttctaatttt agtaatcaga ttttatcaat aaattactat
     6601 tctattaatt taattaaata acctttaaat ttaattataa aaactgttgc agaaatttct
     6661 acaacagttt aaaaaattta ccttacaaaa acttatttta taacaagaga gtatattata
     6721 aggctagtac agcccatttt ttgcactgag aaattctttt gccatcatca ccttgttctt
     6781 tgtcatatgc aaattgatta agcatttcac atggaaatgt atcacataga ccacaatgta
     6841 taaggttttt atcttcacaa caagatttta caggacattg ttcaccccaa aatggtttct
     6901 caatatctgt acaaccttta caattgactt tttccttgta tccacattca taacataaaa
     6961 ttccacatct tgattctatc attttaagtc actccttaaa tataaatttt attatgattg
     7021 tatatcaaaa tttatacttt tcattgtaaa aatcggacaa attttttata taggttgttg
     7081 gattaacacc acaaatagat ttaaaatcat ttataaaatg agattggtcg taataaccaa
     7141 tatcttgtgc taaagttgca aatggtcttt tattgttttg tacttcttgt aatacaaggt
     7201 ttatacgaag taatctaagg tatgatttaa cactcatccc aagagaatta ttaaaaattc
     7261 tatttaaatg tcgttcacta taacaactaa tttgtgaaat gtttttaaca gacataatag
     7321 agttctgttt tctagcattt tcaagaattg gtatagtcat atctactata tttgatttca
     7381 ataagtatga taagaataac atatctaatt gttctactaa ttcctttata gtacttgttc
     7441 tttcaaaaat ggaattaacc tctaagctaa ataatgtgtt aaaatcttca agtgaaattt
     7501 ttaaatctgt agattctctt tgagaaagac ctgtcaaata atatactcca cctgggcgaa
     7561 actcaacgaa tactctaaaa agtacatttt ctatatcatt ttttacaata gtagtttttg
     7621 ttgtggctcc ccagaatgcg ctttctatac cttttttgtc aaatttaaat atcatacatc
     7681 cactagcatc aggtattaat gtaagctttt ctttaatact tgtatctgga atagatattg
     7741 tatagtgtgc tatatactgt cttaacaatt tatgtggcaa aatatatgta tactgtttgc
     7801 aggtatttaa aatgttattg attattttat tcataagtat atcctcctga tatataaaaa
     7861 ataagtatac taatttattt tttatataat aaaccagttt tgttttaatt gaaatattct
     7921 a
//
LOCUS       DAMJWO010000120         7850 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.125, whole genome shotgun sequence.
ACCESSION   DAMJWO010000120 DAMJWO010000000
VERSION     DAMJWO010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7850
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.125"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            249..2561
                     /locus_tag="PC366_003392"
     CDS             249..2561
                     /locus_tag="PC366_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HDF2578875.1"
                     /translation="MDIIKKLSHGCTLDCHDCCKFNVYTKENNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDGVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGGPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYVQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKKYLSSLELSFLIDECGVKENDIREL
                     VDLYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSQSYGEDREFYVSNISKFIEESLKNTSNKVNYASDELDTTSNKVNYISDELD
                     TTSNKVNYVSDELDTTSNKVNYVSDELGMALHKVNCVSDELDMTSNKVNYVLDELDIT
                     SNKTDYISNELYNLSNKSIKDNIPIKMAVITKSNMLNQLPDLVELERVFSKIKFKVCF
                     DMFMTDTATLCDMFIPCTNTLESEDIIYSSMTNPYITYNERAVKPAHKLMDEYYFFME
                     LAKKMGLNDYPFVEKRTYLEKVIEPLKRFDKNLDIEKLKNNYFTIHNLVAWEDKKFET
                     PSGKYELYSESIKNLGISPTPVYISNKYKEIEDKNISFRLLTNHHADTLFSQHFMDKK
                     SIAQAYINQRMAKKVGIEDKDIVILRSKKAKINVQINIDDGVGNYIVKMYVGWWKKHG
                     NPNSLTDTGISDFGGQVTYNESMVEIIRQN"
     gene            2649..2984
                     /gene="spoIIAA"
                     /locus_tag="PC366_003393"
     CDS             2649..2984
                     /gene="spoIIAA"
                     /locus_tag="PC366_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HDF2578876.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            2998..3426
                     /locus_tag="PC366_003394"
     CDS             2998..3426
                     /locus_tag="PC366_003394"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HDF2578877.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            3449..4213
                     /gene="sigF"
                     /locus_tag="PC366_003395"
     CDS             3449..4213
                     /gene="sigF"
                     /locus_tag="PC366_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HDF2578878.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAVKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
     gene            4493..4930
                     /gene="spoVAC"
                     /locus_tag="PC366_003396"
     CDS             4493..4930
                     /gene="spoVAC"
                     /locus_tag="PC366_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HDF2578879.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
     gene            5084..6097
                     /gene="spoVAD"
                     /locus_tag="PC366_003397"
     CDS             5084..6097
                     /gene="spoVAD"
                     /locus_tag="PC366_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HDF2578880.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLSDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGDGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGVDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            6111..6473
                     /gene="spoVAE"
                     /locus_tag="PC366_003398"
     CDS             6111..6473
                     /gene="spoVAE"
                     /locus_tag="PC366_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HDF2578881.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            6656..7672
                     /locus_tag="PC366_003399"
     CDS             6656..7672
                     /locus_tag="PC366_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDF2578882.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFVGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDRSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAIFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
BASE COUNT         3152 a          800 c         1455 g         2443 t
ORIGIN      
        1 taataacaat tcaaaataaa taacttatgt aagaaccgta ggaactacgg ggatagcctg
       61 tggagaatta gtaagacata ttttagtatg caaaattctg tgaagcagga acactgtgac
      121 tttagtcatg ggaggttcag aaaatatagc tatgttttat atactgtagt tttgaacata
      181 gaaagtttaa taaattatag tatatattaa tttttaataa ggtaagaaag tagaaagaag
      241 gatattttat ggatataata aaaaaattaa gtcatggatg tacattagat tgtcatgatt
      301 gttgtaaatt caatgtttat actaaagaaa ataatgtagt aaaaattgaa ggagataaaa
      361 atcatcctta tacaaaaggt tttatatgca aaaaagggat ggctcattta gatagattaa
      421 atcataaaga tagaataaag actcctatgc ttaaagttga tggagtatgg aaagagattt
      481 cttttgataa ggctatagaa ataatggcag aaaagcttac atactataaa gaaaagtata
      541 catcaaagtc tgtcatgcat tatgaccaat atggaagtgg gtctgtgcta aaatacatag
      601 gagatatatt ttttaatttt tatggaggtg ttagcagaca taagggtggt ccctgttgga
      661 gtgcagggat gcatgctcaa aaatatgatt ttggagtagc taagagtcat gctatagaag
      721 atatgttaaa tagtaaaagt atatttgtgt ggggaaaaaa tccagcatat actacaattc
      781 atactatgca aataattaaa aaagctaaag aaaaagggat aaagatagta gtgattgacc
      841 ccatatatac aaaaacagct caaatagcag ataagtatgt acaggtaaat cctggaacag
      901 atggagcttt agctatagct atggcaaaaa ttatagtaga agataaatta tatgatgaag
      961 aatatataaa ctcgtatgtt attggttttg aagaatataa aaaatattta tcttcattgg
     1021 aattaagttt tttaattgat gaatgtggtg ttaaagagaa tgatataaga gagttagtgg
     1081 atttatatac taacaaatat tcaagtataa atgttggata tgggcttcaa aaatataaaa
     1141 atggtggaaa cacaataaga gcgatagatg ctttaggtgc tataactggt caaataggat
     1201 ttagtggtgg aggggtaaac tatgctaata aagtttatcc aagtgttata aattctgacc
     1261 cttacaatag ccaatcatat ggtgaagata gggagtttta tgtaagtaat atcagtaaat
     1321 ttatagaaga atctttaaaa aatacatcaa ataaagtaaa ttatgcatca gatgaacttg
     1381 atacaacatc aaataaagta aattacatat cagatgaact tgatacaaca tcaaataaag
     1441 taaattatgt atcagatgaa cttgatacaa catcaaataa agtaaactat gtatcagatg
     1501 aacttggtat ggcattacat aaagtaaatt gtgtatcaga tgaacttgat atgacatcaa
     1561 ataaagtaaa ttatgtatta gatgaacttg atataacatc aaataaaaca gattatatat
     1621 caaatgaatt gtataattta tctaataagt caatcaaaga taatattcct ataaagatgg
     1681 ctgtgataac taaaagtaat atgctgaatc aactgccaga tttagtagaa ttggagaggg
     1741 tgttttcaaa aattaaattt aaagtatgtt ttgatatgtt tatgactgat acagctactt
     1801 tatgtgacat gtttataccg tgtacaaata cactagagag tgaagatata atttatagct
     1861 caatgaccaa tccatatata acctataatg aaagagctgt aaagccagca cataaattga
     1921 tggatgaata ttatttcttt atggagctag ctaaaaaaat gggattaaat gattatcctt
     1981 ttgtagaaaa gagaacttat ttagaaaaag tgattgaacc acttaagcgt tttgacaaaa
     2041 atctggatat agaaaaactt aaaaacaatt actttactat acataacctt gttgcttggg
     2101 aagataagaa gtttgagact ccatctggaa aatacgagct ttattcagaa agtataaaaa
     2161 acttgggaat aagtccaaca cctgtatata taagcaataa atataaagaa atagaagata
     2221 aaaatatttc ttttagatta ttaactaatc atcatgcaga tactttattt agtcagcatt
     2281 ttatggacaa aaaatctata gctcaagcat atataaatca gagaatggct aaaaaagtag
     2341 gtattgagga caaagatatt gtgatattga ggtcaaaaaa ggcaaaaata aatgtacaaa
     2401 taaatataga tgatggagta ggtaattata tagtaaaaat gtatgttggt tggtggaaga
     2461 aacatggaaa tcctaatagt ttaacagaca ctggtatatc agattttgga ggtcaggtaa
     2521 catataatga aagtatggta gaaataatac gacaaaacta gttaaatttc attgaaggaa
     2581 taaaaatata attatagaat tgattaaaag ttactatttt tacaaaacta ttgaaggagg
     2641 gatttttgat ggtaaattat tccttagaac ataagaatct atacatagaa tttatgtgct
     2701 cagaactaga ccaccatgta gccaatgaaa taagggaaga aatagataac ttattaagtg
     2761 taaatcaagt aaaaaatgtt gtatttaatt ttgaaaatat taattttatg gattcttcag
     2821 gtataggcgt catcataggt agatataaaa agatttctaa tgaaggggga cgagtttcag
     2881 taattaatat aagttcacga gttaagaaga tttttgattt atctgggtta aataaaatta
     2941 ttggcattta tgatacgtat gaagaagctc taagttcttt gtagggagga gtatgtgatg
     3001 aataatatta tggaagttaa attttcggca atatctgaaa atgaaagttt agcaagagtt
     3061 atagtagcat cctttgcagc taagttagac ccaacagtag atgagttagt agatataaaa
     3121 actgctgtct ctgaggctgt tacgaatgct ataatacatg gatatgaaga agacagttct
     3181 aagtttgttt tcttaagatg tgagatagaa ggaaatacta taaagattat agttgaagat
     3241 gaagggtatg gaatagaaaa tgtggagaag gcaatggaac cactttatac atcaaaacca
     3301 gaacttgata gatcaggaat gggattcaca gtaatgaaaa gctttatgga cgatgtagag
     3361 gtaagttctg taaaagataa tgggactaga attgaaatga ctaaaaaaat aaatgtgcct
     3421 aaataaagtc caaaagtgag gttttattat ggaagtaact gttgccagag aagaaaaaaa
     3481 acctcttctt agtcatgaag agactctaga acttattgaa aaagttcaaa atggagatga
     3541 agaggcaaaa gaaatattaa tatcaagcaa tttaggtcta gttaggagcg ttgtatctag
     3601 atttttaaat ataggatatg atagagaaga tttatttcag ttaggttcta taggcttaat
     3661 aaaatcaata tataaatttg acccaaaatt taatgtaaaa ttctctactt atgcagtacc
     3721 aatgatttta ggtgaaataa agagatactt aagagatgat ggtatgataa aagtatcaag
     3781 gtcgttaaag caaatagctg taaaggcaaa gatggaaagt gaagctttaa ctaaaaaatt
     3841 aggtagagag ccaagtatag aagaattagc taaagcaata gatgtagaaa aagaagattt
     3901 agtaatggct atggaagcta atttcaatgt tgagtatttg caaggagtta ttcatgaaga
     3961 ggaaggttct ccaatatgcc ttattgataa aataagcatg aaaggagaaa gtgaagaaga
     4021 aaaagtagtg gataacatat tgttaaaaga catacttgga agactggata agagagagcg
     4081 tcaaataata gttctcagat actttgaaga catgactcaa agtgaaatag gagagatgct
     4141 caatatatca caagttcaag tatctaggat agagaagaaa gtattgtcta agttaaaaga
     4201 atatatatcg tgataatact tatgatatgt agaataacaa aatataataa atatattact
     4261 aaaataaaat gtaataactt tttatgttaa gtttttaaat tattaaaaga tactaaaata
     4321 ataaaaagca ttaaaaaagt aaaaatataa aaacaaggtg tctttatgga aaaatagatt
     4381 ttttctttat taggcatctt ttttattttt tgaccaaact ttagatagtc aaaataaata
     4441 ataggtttat ttttttaaaa ttaacaaata atactttaga gaggtgttta gtatggataa
     4501 aaattataaa aaatatgtag accaaataag cccaaaacct acatatttaa aaaactatac
     4561 acttgcattt attgtaggtg gaattatttg tatgataggg caagcaataa atgatttgta
     4621 tatgaaagtt ggaggtcttg ataaactagg tgctagttct gcaacatcaa taacattaat
     4681 atttataggg gcatttttaa ctggattagg agtttacgac ctaataggaa aaagagctgg
     4741 agctggttct ataattccaa taacaggttt tgctaactca atagtatctc cagcaatgga
     4801 gtataaaaga gaaggctatg tattaggtgt aggtgcaaac ttatttaaaa ttgcaggacc
     4861 agttttagtt tatggtatag gttcttctat tttatgtgga attatttatt atatttttaa
     4921 gatgttttag atgattttta tttaatttaa attttattaa ttatgaagaa ggtataaaat
     4981 ctgaaaatag ctactaaagt aactaattga aaaataattg tgcagattta attaatatta
     5041 aaaatttgaa tagtaaaatg caaaattaaa aaggtgtgaa aatatgaaaa ataaaagaat
     5101 tggaaaaaga acagtcaagt tagaaaataa accaaccata atatcaactg gaactatagt
     5161 gggtcctaag gaaggtgaag gaccactaaa ggactatttt gatatgatta tgactgacga
     5221 tttatatggt gaaaagactt gggaattagc tgaaagtaaa atggtagaga ctgcatccca
     5281 acaagctatc caaaaggcag gtaaaaaatt gtcagatgta aattatatgc taggtggcga
     5341 tttaataaat caaatagtgc cagcatcatt tgcagcaaga gaactggcta ttccattttt
     5401 aggtatatat ggagcttgtt ctacaatggc agaaggtctt tgtataggtt ctatgcttat
     5461 agatggtggt tttgctgatt tagtactgtc aggtacatca agtcactatt gtacagcaga
     5521 aagacaattt agattcccac ttgaacttgg aaatcaaaaa ccaatgacag ctcagtggac
     5581 agttacagga gcaggaagtg tattattagc tcctaatgga gacggtccaa aagtaaagta
     5641 tgttactgtt ggtaaagtaa tagatgaggg tattgatgat ggtaataata tgggaccagc
     5701 tatggctcca gcagcaatag atactatcta ctcttacttt gaagatacta atgatgaccc
     5761 aaatagcttt gatataattg ctactggaga tttaggtact cttggaaaac agatagcaga
     5821 agactttcta aaagaaaaag gtgtagatat atcaaaagtt tatactgact gtggtataga
     5881 gatgtttaac cttaaagaac aagatgtcca ctgtggtgga agtggatgtg ggtgttcagc
     5941 tacagtgttt gcaggatata tatatgataa gttgagaaaa aaagaattta acaaagtaat
     6001 gcttgtatca acaggagcac tactttcacc gacaagtaca ctacaaaagc agacaatacc
     6061 atgtgttgca catgcagtag taatagtaaa tgagtaggaa gtgatataat atgttaatgg
     6121 actatgtaag agtatttatt gtaggtggaa ttatatgttt aatagcccaa gtaatgatgg
     6181 attatttcaa aatgcaaact ccatatgtta tggtaacgta tgtaacaact ggtgtagttt
     6241 taacttttct aggactttat gagccattag ttaagtttgc agcagcaggt gcaacagttc
     6301 ctataatagg atttggatat tcacttgcta caggagtaat aaaatcaatt caaagtgatg
     6361 gttttttagg tattttttta ggaggtacaa ctgctacagc tggtggaata gcagcagcta
     6421 tattctttgg atatattatg tcagtagtat ttactccaaa agcaaaacca taaatcttta
     6481 ttaaaagaat aataagtttt tgaaataata actttttata aagcaggtgg atatctttta
     6541 gattccacct attttttata taaagaagcg tttacataat tgaagttgac aattatttac
     6601 aacatagtgt agtattatat tatcaaaata aaatgaagtg aagtagggga taaagatggt
     6661 aactattaaa gatattgcaa ggaatctagg tatcagttat tcaactgttt ctaggtgctt
     6721 aaacaataat cctaatgtat ctgaaaaaac aaaaaagaaa gtagtagaag aggcaaatag
     6781 actagggttc cattttaatg taaatgcaag aaatttagca aaaaaagaaa ctaacaggat
     6841 aggggtaatc ttttcaaata attttaatca tcaagatact agaaagtttt ttagtgatat
     6901 aatggatagt tctataaatt ctattgagac taataaatac gattttataa tacagcctaa
     6961 taataacatt agtggtgata gtaatgtata taaaatggta aatggacaaa tggttgatgg
     7021 attagtaatt gtgtctcaat caataaaaaa agaagagtat gattttttaa aagacaataa
     7081 ttttccacat gtatttatat attttaaacc atcttttgta ggagaagtag acaatttctt
     7141 ttgggacgat aacgtgtatg gaggttatat agctaccaag catttaattg accatggtca
     7201 taaagacata ataacagtaa cttcagatga taggagttca aaaatgcatg aagatagaac
     7261 taagggatat ttaaatgcta tggaagaggc aaatttaaag accgaagtca ttaaatctaa
     7321 aatggatttt gaatctcaag ttgaattttt agaaaaatat attgataaaa taaaaaaagc
     7381 ttcagctata tttgtacaac aagatgtacc tgcgatttct ataatacaag agttaaaaac
     7441 tacttatggt ataaatgtac cagaagatat ttccataata gggtataata atattgaatt
     7501 aatatcatat tttaggtcgc atttatcaac aatagatgac ccaagagagc aagttataaa
     7561 aaatggagta gatagtttag taaatataat aaataaaaag agtacagaac acattccaag
     7621 aaaattatat ccaaggttaa taatacgaaa tagcgttaaa agaataaagt agtaagcttt
     7681 taagtatcaa aagtttatta aaaatattat agattatgtg aagtttttta acaaacaata
     7741 taaataaaaa ttaaaaggag taggtgtata taagtacatt gtactccttt atttattgag
     7801 atagttttta taatatgaat gaataatttt attcaattat ttgaaaatcc
//
LOCUS       DAMJWO010000121         7745 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.126, whole genome shotgun sequence.
ACCESSION   DAMJWO010000121 DAMJWO010000000
VERSION     DAMJWO010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7745
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.126"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(242..2521)
                     /locus_tag="PC366_003400"
     CDS             complement(242..2521)
                     /locus_tag="PC366_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDF2578883.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEESFEVDNILSILKRQAINSSFKRM
                     GVILPNGTAYTTDGYIEDFSKRDYFLKSMQGEVVITEKLKDVIEDDKNTNSNINVYSV
                     PIYKDNEVKGVIFATHSTKLYEKILSVPTFNGKGYSYIARSNGNIVLNPSSKNANSTK
                     ENLFSYIGRSDSISKSSINNMKSNIKNFKSGSLSYSMFGKGYYLSYAPIGINDWYLFS
                     EVPKTAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRESIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTTVKRKYLKVYEIYAENLKETLIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGVFIPIFEKNGFITELDMF
                     VFAQVCKNFKRWENENFPTFPISINLSRVHLENPGFISELERITKEYEIEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRFIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSLNRKETN"
     gene            complement(2792..4246)
                     /locus_tag="PC366_003401"
     CDS             complement(2792..4246)
                     /locus_tag="PC366_003401"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HDF2578884.1"
                     /translation="MKLNDIIQGLDIINVKGELNIDINNVQYNSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVEIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTKADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAIAEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            4410..5279
                     /locus_tag="PC366_003402"
     CDS             4410..5279
                     /locus_tag="PC366_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDF2578885.1"
                     /translation="MDNKIGYLNDNFKIFNIRDKKDIQFEYHNHDFNKIIIFINGNVT
                     YFVDGIPYKLKPWDILFISNNEIHKPVIDSNVFYERIAIWISPEFMKKNSDATSDLEK
                     CFKIATENKCNRLRLNIHDIESIKSFIEQINISESNTEFGNEILRNALFIQLMIFLNR
                     IFLKNENMESTEDVFYDETIKKVLNYINSNIDDKLSIDSISSEFFISKYYLMRKFKSH
                     TGTSIHNYIVQKRLILAKSLITNGYLMSEVCNKCGFNDYSSFVRAFKKNYGVSPKNYI
                     NNKNPLDITLLDE"
     gene            complement(5493..7565)
                     /locus_tag="PC366_003403"
     CDS             complement(5493..7565)
                     /locus_tag="PC366_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2578886.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLSHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMVDNSMYASIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAIMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDESETNAEVIEMSKNELASEILIALGNKDNLKSLDACITR
                     LRLVVNDINKVDKEKLKLLGAAGVMVIGNNVQAIFGPKSDSIKSDIKDIIEGKTKVES
                     TVTKNVDKNKVKKNMEVANMENALVEKIDSLTNGEILDIEEVPDSVFSSKLMGDGFAI
                     KSSDGLIYSPVDGTIGVIFPTKHAIIIKSKKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNCLSTISPVVFTNLEQNQKLSIKKGITTAKEENRVSIL
                     RYDIEKIG"
BASE COUNT         2634 a         1284 c          819 g         3008 t
ORIGIN      
        1 ctatagaaat tactattatt actatctaaa gtattttgct ataatcccat atactcttac
       61 ctcaaaaaca ttcaaatgga aaaaatacta catattaata aactttgccc aataattcct
      121 aaaataatat cctaacaatg atttatgttt ttataatagt atatttttac ataaaaaagt
      181 gaacattgat taacaaagtt cactttttta taaattttta tgttataatt cacaatttta
      241 tttaatttgt ttcttttcta tttaaactat atctatctaa tattaatttt tcatattctt
      301 ctattggcat tggtctagca aataaaaatc cttgggccat atcacaacct ataaacctta
      361 aaaactctgc ttgctctaca gtttcaacac cttctgaaac aacttttata tcaagttgct
      421 ttgccatttg aacaatactt gaaactacaa tttgactctt ttttgcattt cccactgtta
      481 taaagaattg cctatctaat ttcaatacat caattggcat atctttaagc atatttaaag
      541 aagaataacc agaaccaaaa tcatccatag aaattttaaa tccaacagat ttcaaagttt
      601 gcattatttt aaataatatt tttgtattgt caaatattgc actttctgtc aattcaatct
      661 caattaaatt tggttcaatt tcatattctt ttgttattct ttcaagctca gaaataaaac
      721 ctggattctc aagatgtact cttgataagt ttattgatat aggaaatgtg gggaaatttt
      781 cattttccca acgtttaaaa tttttacaaa cttgggcaaa tacaaacata tccaattctg
      841 ttataaaacc atttttctca aaaataggaa taaatacacc tggacttatt agaccttttt
      901 tgggatgttg ccaacgtaca agcgcttcag cacctacaat tttagtagtt gataaatcaa
      961 ccttaggctg taaataaact ttaaattgtt cattttttaa agcatcatgc atttcttgtt
     1021 caatatcacg ttcttctatg agagtttctt ttaaattttc agcataaatc tcataaactt
     1081 ttaaatattt tctttttact gtagtttttg caatcatagc tttgtcaaga caggtagaaa
     1141 tatttgtttc tccctcttca acaaaatata cacctatgga tggaattaaa ttgagttcta
     1201 ctcccaaact tgtttttatc attgacaatt ttttacgtat aagttcacat atttctataa
     1261 ttgactctct attatttttc ttttcaaata ttatagcaaa attgtcattt gaaattcttg
     1321 aaaatacaga ttgctcttta aatatattct taattatctc tgctatttcc tttaatactc
     1381 tatctccttc ttcataccca aacctatcat ttactagctt aaacttatct atatcaaaat
     1441 aaattaaaac tagattcttt ttctcatgag aggataaaaa ttttcctcct tcaagattaa
     1501 atttatttga attgccaata cctgtaacgt tatctttaaa agcaaattct tccaattttt
     1561 ccttactctt tttatgtata aatagtatat aaattgttaa tgccgtaaag attataatca
     1621 acactacaca tgctgataat gtaagtttta taatagcgta tgatttctca gatatagcag
     1681 ttttaggaac ttcagaaaaa agataccaat cattgattcc tattggggca taacttaaat
     1741 aatatccttt tccaaacata ctataactta atgaacctga tttaaagttt tttatatttg
     1801 acttcatatt attgatacta gattttgata ttgaatcact tctgccaatg taagaaaata
     1861 aattttcttt agtagagttg gcgtttttgc tgcttggatt taaaacaata ttaccattac
     1921 ttctagctat ataagaatat ccttttccat taaatgtagg tacagaaagt attttttcat
     1981 acaacttcgt actatgtgtg gcaaatataa ctcctttaac ctcattatct ttataaattg
     2041 gcacagaata tacattaata ttactattgg tatttttatc atcttctatt acatctttta
     2101 atttttctgt tataaccact tctccttgca ttgattttaa gaaataatct cttttagaga
     2161 agtcttctat ataaccatct gtagtgtatg ctgtaccatt tggtaaaata actcccattc
     2221 ttttaaatga actattaata gcttgtcttt ttagtataga aaggatatta tctacttcaa
     2281 aagactcttc tccctcaata aatattgaaa ttgactctag taactttata tctccattaa
     2341 tttgtttttt taacacattg acgctttgat ttgctatttc tgaaagatat tgattcgttt
     2401 cttcacctaa tgtcttattc aaccttgaac cataaatcaa acaggaaatt gtaattacta
     2461 agatacttat gacagcaatt atggacaaac catacctatt attttttgca tcacttaaca
     2521 ttatgcttcc tgcctttctc gaatctatgt atgtataatc attatcttat gacaattatt
     2581 gtaaacattt tataataata cttatttttc catatttact gtaattatac aaaattataa
     2641 actttattac aacaataaat taattaatat agatattagg gtttatatta ttgcattatc
     2701 tattttacaa tcatttacat ataaaaaaat gtaatatcaa agtgaaactt gatattacat
     2761 ttttgttctt gtattttgtt taatttttat gctacatttt acttaaacac tcatttgcaa
     2821 cttctttatc atcaaaatga tgcttaactt tacctataat ttgataagtt tcatgtccct
     2881 tacctgttat aattacaaca tcatcctttt ttgccatact tatagcttct gctatagctt
     2941 gttctctatc aacaacaaca tggtaatttt cttttttctt gtcaattcct tcaagtatat
     3001 cttttattat tgcctctggt tcttcagttc ttggattatc agaagttata atacataaat
     3061 cagaatattt ttgtccaatt gctcccatca aaggtctctt ttcagtatct ctatctccac
     3121 cacatccaaa cacagaaatt atttttcctt ctgcaaattg ttgagttgtc tttagtacat
     3181 tttcaagtgc atcaggagta tgagcatagt ctacaattac acttatacct ttatcatttg
     3241 gaactgtttc aaaccttcct gatactccat tagaaagtct aagaccttct ttatatattg
     3301 gtttaggtat gccaagtaca tagcaagcag ctataactgc taaagtatta tatactgtaa
     3361 acattcctgg aactggtata aatattactt cttcatatga aggtgttatt aatctataag
     3421 atactccatc cgaatctgat tttatatctc tagccataaa atcagcctta gtatcaacac
     3481 cataagtgta acaaggtaca tttatacctt ttatattttc atatatcttt tttccacctt
     3541 catcatctat gtttattata tttgccatag tagtcttaaa aaataatttt tcttttgctt
     3601 ttctataatc ctctaaatct ttatgaaaat ctaaatggtc tggtgttaaa tttgtaaata
     3661 tgcctagttt aaagtctgtt tcatcaactc tatttaatgc caatgaatgt gatgaaactt
     3721 ccatcgcaca gtagtcacat ccattatcca acatattatt aaaatgatat tgtaaatcta
     3781 tactttctgg agttgttgaa ttggaaacaa tgtctttttc tccgtcaaaa atttttatag
     3841 ttcctataag tccaacttta ttcttattta aagttaatat ctcatttagt atagtagtta
     3901 tactagtttt tccattagta cctgtaactc ctataacgtt aaatttctga gatggatgat
     3961 tataaaaatt atcagctact tttgccatat cttttcttgt atcttttacc tttataaatg
     4021 tacatccttt tatttctaca tcttcttcaa caagaaatgc acttgctccc ttttctatgg
     4081 catcttttat atacttatga ccatctgaca caaatccttt tatacatata aataatgtac
     4141 cttttgtaac ctttcttgaa ttatattgta cattattaat atctatattt aattcaccct
     4201 tgacattgat tatatccaac ccctgtataa tatcatttaa tttcataaat gctttcctcc
     4261 ctttaaactc tttctgctaa aattacacta catataatat tatattaaga attttttact
     4321 atgtgaatgg ttaaaaatgc ttgaaatatt gcaaaaaatg ctctataatt ttctataata
     4381 taactgagga aaggtcttct ataaaaacta tggataataa aatcgggtac ttaaacgata
     4441 actttaaaat atttaatatt agagataaaa aagatataca atttgaatac cataatcatg
     4501 attttaataa gataattata tttataaatg gaaatgtaac ttattttgtt gatggtattc
     4561 cctataaact aaagccttgg gatatactct ttatcagcaa taatgaaatc cataaaccag
     4621 ttatagattc aaatgtcttt tatgagagaa ttgcaatatg gattagccca gaatttatga
     4681 aaaaaaatag tgatgctact agtgacttag aaaaatgttt taaaatagct acggagaata
     4741 aatgcaatag attgcgttta aatatacatg atattgaatc tattaagagt tttattgagc
     4801 aaataaatat ttccgaatcc aatactgaat ttggaaatga aatattgaga aatgcattat
     4861 ttatacaact tatgatattc ttaaacagaa ttttcctaaa aaatgaaaat atggaatcaa
     4921 cagaagacgt tttttatgat gaaactatta agaaagtatt aaactatata aattcaaata
     4981 tagatgataa gctttcaata gatagcatat cgtctgaatt ttttataagt aagtattatc
     5041 ttatgagaaa atttaaatct catactggaa cgtctataca caattatata gttcaaaaaa
     5101 gattaatttt agcaaagtca ctaataacca atggttacct tatgagtgaa gtttgtaata
     5161 aatgtggatt caacgattat tctagttttg taagggcatt taaaaaaaac tacggtgtat
     5221 ctcctaaaaa ttatataaac aataaaaatc ctttagatat tactctttta gatgaataga
     5281 taatttatgt aaattttatt ttaataaaaa cttgaagtat tagtgtattt atcttactaa
     5341 tacctcaagt tttttaatgt tttaaaatat atcaaaatat aatgatatat atttctatta
     5401 cttaaaatat atattaaata aattgcatgt taactgaacc tatttatata tttattaaat
     5461 ctcacataac ttttagttat actatcatat agctatccta ttttttcaat atcatatctt
     5521 aatatactta ctctgttctc ctcttttgct gtagttattc cttttttaat gcttaatttc
     5581 tgattttgtt ctaaattcgt aaatactaca ggacttattg ttgatagaca atttttttca
     5641 atatattcta agtccatttt aactaatttt tctcctgctt ttacttcatc tcctacattc
     5701 acaaatactt caaatccatt tccttctaaa tttacagttt ctatccctaa atgtataagt
     5761 atttctactc cacttttttt ggattttatt attattgcat gcttagttgg aaatataact
     5821 ccaatagttc catcaactgg tgaataaatc aatccatcac tagatttaat tgcaaatcca
     5881 tcccccatca gtttacttga aaatacagaa tctggcactt cttctatatc taatatctct
     5941 ccatttgtta atgaatcaat cttttctact aaagcatttt ccatattggc aacttccata
     6001 ttttttttca ctttattttt atcaacattt ttagtaacag tactttcaac ctttgttttt
     6061 ccctctatta tatcttttat atcagacttt attgaatccg attttggtcc aaatatagct
     6121 tgaacattgt tgccaataac cataacacct gctgctccaa gtaatttcaa tttttcttta
     6181 tctactttat ttatatcatt tacaaccaat ctaagtcttg ttatacacgc atctaggctc
     6241 tttaagttgt ctttatttcc taaagcaatt aaaatctctg atgctaattc attcttagac
     6301 atttcaatga cttcagcgtt agtttctgac tcatcttctc ttcctggtgt ctttaaatta
     6361 aattttctta tcataaatct aaatacacta tagtataata ctgcaaaacc aatacctacc
     6421 aagatagcca agtaccatgg agttctatta ggaagaacac caaataataa gaaatctatt
     6481 aatcctcctg aaaatgtgaa tccaatttta actcctaata attgcataat tgcgtatgat
     6541 aaacctgaaa ataaacaatg tattgcaaat aatactggtg caacaaataa aaacgcaaac
     6601 tctattggct cggttattcc tgttaaaaaa gaggttaatg ctgctgatgc cattatacct
     6661 gctacaaatt ttttcttttc tggctttgct tcatgcacca tagcaagagc tgctgctgga
     6721 agaccaaaca tcataaatgg aaatgcacct gtcataaaag tacctgctgt gaaatttact
     6781 ccatctttaa gttgagcaaa gaatatcttt tggtcaccca ttacaagctc accagcttta
     6841 tttacatatt ctccaaattg ataccaaaat ggattatgga aaacatgatg caaaccaaat
     6901 ggtattaata gtctttccaa agaaccttcc ataaatgctg ctagtgtttg atttgcttct
     6961 ataacatttt ttgagaaact aagtaatccc tcttgtattg gaggccaaat aaaagacaat
     7021 ataattccta ttgctatagc aactaatgaa gtaacgattg gtacaaatct tttacctgca
     7081 aaaaaaccta gatactgagg taattcaatt ttataaaact ttttataaag ataagcagcc
     7141 actatcccta taataatacc accaaatacc cctgtttgaa ttgttggtat tccaacaata
     7201 cttgcataca tagaattgtc taccatatct tctgtaacac ccgccataac acccatagat
     7261 gtattgagaa ttaaaaaacc tactatggct gccaatgctg caacaccttc tccttcagtt
     7321 aaaccaacag ctaccccaac tgcaaatata agtggtaagt tattaaatat aatttgacct
     7381 gaactttcca ttatacttat tataagttga aatgtaggat tcgccaaagc tggaaaatga
     7441 gacaacaatg cgtctcctgc taaagcatta ctcacgccaa gtaatatacc tgctgcagga
     7501 agtaatgcaa ctggtagcat tagagatttt cctacttttt gtaaaacacc aaatactttt
     7561 ttcatttact tttctctcct tattatttta tattttttta aataaaaaag acttaagttt
     7621 ataaaaagtt acattagtat acttaattct aaaattaaac ttatgttaat ataaataaac
     7681 ctatattaac ctaatttcag aattaaaaat aaactattat aattttttta taaacataag
     7741 tcttg
//
LOCUS       DAMJWO010000122         7460 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.127, whole genome shotgun sequence.
ACCESSION   DAMJWO010000122 DAMJWO010000000
VERSION     DAMJWO010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7460
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.127"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..830)
                     /locus_tag="PC366_003404"
     CDS             complement(<1..830)
                     /locus_tag="PC366_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDF2578887.1"
                     /translation="MDFINKMRIRNTTIFIVLIISMILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGACLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVKNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILIIVGILGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIRFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQIS
                     "
     gene            complement(902..2032)
                     /locus_tag="PC366_003405"
     CDS             complement(902..2032)
                     /locus_tag="PC366_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2578888.1"
                     /translation="MKFKSNVLKQFFLIAMVIFMVGGLIGCSKSDKENKQASTGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTEEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDMA
                     TSELNKTVQKVEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     regulatory      complement(2260..2441)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(2494..3387)
                     /locus_tag="PC366_003406"
     CDS             complement(2494..3387)
                     /locus_tag="PC366_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HDF2578889.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDKEGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVNKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKIEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMEKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNKLNIC"
     gene            complement(3467..4369)
                     /locus_tag="PC366_003407"
     CDS             complement(3467..4369)
                     /locus_tag="PC366_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HDF2578890.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNVSSEDIIKLKTIINESIFYNYDVFKRERCTVHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDDSFEEPQKTVYFTKRVTKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSAVPFPIK
                     LKVCSRVNGEERQSSNTGLFISDVSDIVSELSKGMTLEAGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            complement(4419..5579)
                     /locus_tag="PC366_003408"
     CDS             complement(4419..5579)
                     /locus_tag="PC366_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF2578891.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQIDKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNMD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            complement(5735..6040)
                     /locus_tag="PC366_003409"
     CDS             complement(5735..6040)
                     /locus_tag="PC366_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HDF2578892.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGNEISFKLKDKTVKTITALDNI
                     TIYHKLAIKDMAQGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            complement(6138..7112)
                     /locus_tag="PC366_003410"
     CDS             complement(6138..7112)
                     /locus_tag="PC366_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HDF2578893.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
BASE COUNT         2377 a         1427 c          800 g         2856 t
ORIGIN      
        1 tttgaaattt gtggcactgc aagtccaata aaccctatag gtcctgcaaa tgctgatact
       61 attgctgcta atatactaga tataaacact atcaaaactc taaaaaatct tatatttatg
      121 ccaatacttt ttgcatactc ttctcctaat aaaaaagcat ttaaaggttt tattatgaat
      181 acagtcatca aaagacctaa tataccaact attataagta tttctacctt ttcccatgta
      241 aatccagaaa aacttcccat agaccacata gtaaattctt ttaatttatc actatttgca
      301 aatgattgta acacatttgt tataccacta catacatatc cggtcataat tcctattatt
      361 aaaagagttg ttatattctt taccttattt gcaaataaaa tgactataga cattacaatt
      421 aaagctccta taaaagctgc tacaaatata ctcattgaat ttacactctc aaatcccaat
      481 gtgtatcctc ccaaaatcat gagagctact gataaagtag aacctgaaga tactcctaat
      541 atatacggtt caactattgg gtttttaaaa aatatctgta ataaaatacc tgatactgct
      601 aggcatgctc cacctaccat ggttgcaagt actctaggga ttcttatatt gtatattatt
      661 ttataatgtt ctgtattatc catacctctt aatacaacat ctattacttc tttaaattca
      721 atttttacag agccaaatgc tacacacact aaaaaagtaa gtatcatact tataattaat
      781 actataaata ttgtcgtatt ccttattctc attttattga taaaatccat ttgtatactc
      841 ctcttagcaa agttatatta actaaaatct ataaaaccta tctttttgtg tcctctctgt
      901 actatttatc ataatttata taatgtttga ttttttcacc tgtagtacct gggtggaaca
      961 tctcaactaa atctactatt aattcgtccg tcttatctac tgattgataa taatctggag
     1021 caaacaccca taggtttccg ttttttacaa catccaaatc agccaataca ggtgcactag
     1081 attttataga atctaaattt ggtgcataat ctgaacttga tgagtataca aatatatctg
     1141 catcttttgc aacttcatgc aattgttcaa tacttactcg cccttcattt gaatctattg
     1201 aagcacatgc atttattcca ccagccattt ttatcatatt atccacatat gaatctttag
     1261 gagctatata agcacttcct tcatatacag atgcccatac aactttaggt ttagctttgt
     1321 tttttatttt tttacttact tcttctacct tttgtacagt tttatttagt tcactagtag
     1381 ccatatcttc tttatcataa aatgcagcta ttaaacttgt ccactccatt cttccaaatg
     1441 gattttgctc tttatactca ttgtctacaa cataattaag ccctaattct tttaatttgt
     1501 caataaattt tgtatcagcc tctgataaac cactactcac tatagttaag tcaggattta
     1561 agtctactat tttttcataa tctggtgcta aatttgaacc aacgtaatgt atttttccat
     1621 ctttcattaa atctttaatt tctttaatag tccagtactg ctcttctgtt gttacggctt
     1681 ttatactatc tagttcatct attgttctca gagaacaagc ctgtgttgta gatgctatta
     1741 atacattgtc cacaggcgtt ctaactatat tagcattttt atatttttca ggaattttaa
     1801 tcttctttgg gattaaaatc agttctcgat tatctccatc agttactttt ttaattccat
     1861 cttctaaatc ttcaacacta aatccactag catattttaa ttctaatttc ttaccagtac
     1921 tagcttgttt attctctttg tcacttttac tacaccctat aagacctcct accataaaaa
     1981 ttaccatagc aattaaaaaa aactgcttta aaacatttga tttaaatttc atctctttca
     2041 ctccaatatc ttatttttta tgagtggcta aaaaacttta ataatatatg ctttttaaag
     2101 tatacttatt aaagttatcc taaagtcatc tttaataagt ataacctttt aataaaataa
     2161 aaaacttctc ctaatttaat aaggagaagt tcatatatca actttacaaa aacgaattga
     2221 tacttcattt tattataaat tacaatctcc accctaaatt gaacttatat aatactgggc
     2281 aggtctcctg actcacggct tttcctccat cacccttccc aaaattttta taaatttcag
     2341 tggattttga tttcgtatcc gtatacagta gcgggggctg tagtgaattt tcatcacttt
     2401 ccctattaaa ctaatatagt accctagtat tattttaatt taatttttat taagataatt
     2461 gtaatttatt gttgacctct ttgcaaggtt gatttaacat atatttaatt tattcatcaa
     2521 ttttttaatt tcacatactt gtttttcatt tggttttaca aatggagcag tcatataatc
     2581 acttatttgt aaccctctga tattcatagc ttttttcatt gctggtataa atggattggt
     2641 tattaagtaa aaatccattg ctttattaat atatttttga atttctataa ccttctccat
     2701 atctctatta ttgtaagctt cagcccattt ggagcaaact tctggaatta aatttgataa
     2761 tccccctata caacctgctc ccccagacat tagattatgt ataaagtttt catcataacc
     2821 actataaacc ttaaattctg ggaactctat tttcatagta tttattaaat ctctggtatg
     2881 tcccatcaaa gttactgtat ccttatatcc aactatgttt ttatgttttc ttgcaagtct
     2941 taatgtaagt tctggactta aatcataacc agttctatct ggataattgt ataaatatat
     3001 ttcagcctct gtattcttag ctatttcact ataaaataac tcaatactat catcatcaag
     3061 agagaaataa taagggctta ttatcataac gccatctgct ccactattat gtgcatagtt
     3121 tgaaagttct atagattcat ttatacacat acgacttgta cctataaaca cttttactct
     3181 cttatttaca tgactagtta ctaaatctat aagttctttt tgcatatcca tagacatatt
     3241 aaagaactct ccagtacttc ccattatgac tagtccatct acacctccat ctataagatg
     3301 gtcgtacact tttttattac cttctttatc taaatttcct tcttcatcaa atattgtaac
     3361 aactggtgtc aaaaattctg ctttcataat ttaaactcct aaaatttatt ttaatatgtt
     3421 cattaataca tcagatttag ctttaatatt aattatatta aaacatttac ttaatgtaat
     3481 tttttaaaat tccaatactc tcaatctcac attcaactac atctccacta ctcatatatc
     3541 gaggaggtga aaatcccatc cctactccag aaggtgttcc agtagctata atgtctccag
     3601 cctctaaagt catacctttt gaaagttctg aaactatgtc tgaaacatct gatatgaata
     3661 atcctgtatt agaactttgt ctttcttcac catttaccct actacatact ttaagtttta
     3721 tgggaaaagg aactgcactt ttatgtaaaa tacatggacc taaagaggta aatgtatcta
     3781 atccttttcc tctaaaccat tgaacatgtt ctttttgcaa ctttctagca gaaatatcat
     3841 ttataacagt gtaaccaaag atataatctt ctacctcttc ttttctaata ttaacacctg
     3901 ttttacctat tactactcca agttcaactt catagtctag ttgattattt atctcaaaat
     3961 gaccatctat ctcatcttct ggacctattg cctttgtcac acgttttgta aaataaaccg
     4021 ttttttgtgg ctcttcaaaa ctatcatcaa agtgagtttg agtttcttca agatggtctt
     4081 tatagttcac tcccacacat aagatatcat gtattggttt ttctatagga acatgtacag
     4141 tacatctctc tcttttaaaa acatcataat tatagaatat actttcattt ataatagttt
     4201 tcaacttaat aatatcttca ctagatacat tttgaattaa ttcatttaaa tccttaaaat
     4261 ttctactgag atttaaagag ttaacatcta taataaataa ttcatcttta gaaaaaactc
     4321 cagttctttt acattcattt tctccttcag taaaacttac aaacttcata atctcaccct
     4381 ttattaaaat tctatgtatt tattttctta cttaaagatt atacatagtt gcatactcta
     4441 gctattgcca tttcagtata tccaagggac tctgcttttg attgttttcc atttgctaca
     4501 tctacaacca tatttaacaa atcatctgtt aattcttcca ttgtttgtgg accatagata
     4561 actggactag catcaaaatc catattatct tccatatttg caaaagttat tttatttcca
     4621 gttattttta ttactggtgc tattggattt cctgatggtg ttcctcttcc tgtactaaat
     4681 accactattt gtgctcctcc tgctaccata ccagcaacag atgaagcatc atttccaggg
     4741 gtatccatta taacaagacc tttcttatca atttgtttgg cataatcata tacttcactt
     4801 atttgtctat gacctccttt atgtatacaa ccaagtgatt tttcttctaa acttgttaaa
     4861 ccaccagcta tatttccagg agatggatta ccttctctaa cttcttctcc aaccaatttt
     4921 aatgaatttt catatctatg tactatatgt aatatttttt cttttacttc ttcatttact
     4981 gctctcctag ctagtatatg ctctgcacct ataaattcag tagtttcact taaaattgat
     5041 gttgctccta aatcgacaag tttatcactt aattcaccta ttaatggatt tgctgctaat
     5101 ccacttgttg ggtcagaccc accacattca gttcctagta taagttcaga tattggaaat
     5161 tcttcttttc taagcaaaga agcttcttgt gccatttctc tagcataacg aacagctttt
     5221 tctatagttt ttaaagttcc atgttcttct tgtattacaa gagtttttat tggcttattt
     5281 gttctctctt ttattgcatc aactaccaaa tcattttggc aattttcgca tcccaaagat
     5341 acaactatta caccatatac atttggattt gctgcataac cagccataac atccatagtt
     5401 aattgttggt ctgaatgtac ttgtgaacat ccattctgat tattaaaggt aactgcccct
     5461 tgaacttgtg atgctattat tctagttgta tctgatgcac acacactcgt aggcaatatt
     5521 aatatgtggt ttcttatacc aactcttcca tctggtcttt tatatccata aaatttcata
     5581 ctgatttcct cctaaaatag tctatatact ttttataatt tttatatatt ataattttta
     5641 ttacactcac taatcaaaca gctaaaatcc tatttaaaaa ctatttgaca ctaaaagcaa
     5701 tgaatacaac ttttataact ctataaatat tattttatat attagtcata acttgtttat
     5761 ccaaatcctc tctaacactt ctaacattat gaatatgtac atgttgacca ctttttattt
     5821 cctgatttgc ttctcctata tgttcaccat atttagtaac tttatcacct tgggccatat
     5881 cttttatagc caatttatga taaatagtta tattatctag tgctgtaatc gtttttactg
     5941 ttttgtcttt taatttaaaa ctaatttcat tacctttagc tattgcttca atagctactg
     6001 caacattatc tttttcatca attatcactg catttatcat tattcttgct ctcctttata
     6061 aataatataa ttttattaat atcctaaaat ctaattaaag aatttattat tttaccaaca
     6121 actcactgta atataaatta agctgttatt gtaccatcct cattttgttt tgggaactta
     6181 ggacatccat acttcttagc ccaccaacta gttataagag gtactaatat tgcagtgaca
     6241 actactgcgg ctgccacttg tgttgtagct gttgcaacat atggttgcca tgatgggtca
     6301 actaatgcaa cagcagcagg tacagcaatt gcatttccag cggttgtagc tacagcccat
     6361 cctgcatatc ctggacgttt tcctataaat ttatcacaga atactataaa tatacctcct
     6421 acaaatacag atattaatcc aagtaatact cctgataaac ctccttttag tatacttgca
     6481 agatttatgc tactaccaag tgcaaaccct acaaaaggta cgagtaaatt acaccctggc
     6541 tctaaaaact ctttcatttt tttgtcaaaa tttcctatta tcataccaac aagtattggc
     6601 actattgcag ctaataatga caacaatggc acatttgcaa gacctgaagt cccaagagct
     6661 attaatgtaa aaaatggtcc atcatttaaa gtaagtaaac tcatagttgc acaatctgtt
     6721 tcatctccat atgaagtcat caatgaaaga tatatactac cattactatt tgtaactgca
     6781 cttataacag ccaatgttgt aagaccaagg acaccatcca ttccaaatag ctttcctata
     6841 agtataccta tcaaagcacc tatagcaaat ttagaaccaa gaagtatacc acctctcttt
     6901 aaaacttttg gcatttctct aaattgaagc tgagttccca agcataccag ttgaacccca
     6961 attatagttg cagacccaac acttgaaaat actgctgtcg taaacgaacc tatttgtaca
     7021 atatctgggc aaaaggtatt aatgaaagct gctataaaca ttggcactat catcatacct
     7081 gcaggaattt ttttaataaa atccattatc ataaagttaa tcctcctaaa acatgatatt
     7141 taattactct tattaagttt ttagctttaa ttctaacggc cgtttcggtt cgtatttaag
     7201 aactaagttt ttaattacga atctttgaat taatgatagc attttcctat ttatgagtca
     7261 ataaaaaaaa taaatttttg tcaaattttt ttcaaacttt ctgataatac cttgtatatt
     7321 atcaaatgac ttccttatat gcaaaaatac agcgtattta aaattatata gtattcaaaa
     7381 ctataaagtt tttatacagt gtaaaaaata gataaaatat aaattcataa tattttgata
     7441 tttacatata aaaataacta
//
LOCUS       DAMJWO010000123         7202 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.128, whole genome shotgun sequence.
ACCESSION   DAMJWO010000123 DAMJWO010000000
VERSION     DAMJWO010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7202
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.128"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            15..875
                     /locus_tag="PC366_003411"
     CDS             15..875
                     /locus_tag="PC366_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2578894.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPNAFIIITDIHE
                     ALGNGFKKIE"
     gene            1330..1896
                     /locus_tag="PC366_003412"
     CDS             1330..1896
                     /locus_tag="PC366_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2578895.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLVVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNVRGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLEDIPEYV
                     HKIVFGVSIYKAKKRDQDFGQMNNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            1936..2517
                     /locus_tag="PC366_003413"
     CDS             1936..2517
                     /locus_tag="PC366_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HDF2578896.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTDGKVTNDGDFIFYNNLKHASGAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(2574..3491)
                     /locus_tag="PC366_003414"
     CDS             complement(2574..3491)
                     /locus_tag="PC366_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDF2578897.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     VISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVEYGKKQARKKSRSVNSL"
     gene            3621..5252
                     /locus_tag="PC366_003415"
     CDS             3621..5252
                     /locus_tag="PC366_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2578898.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKIIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFMRTPNDAIKLRDSIENGIKRAVVIGGGF
                     IGLEIAENLSAMGIRVSVVDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIE
                     GENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNNTIIADEYMLTNDKD
                     IYVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPE
                     LNAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQV
                     MGPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGE
                     LDSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGK
                     NSYMAQNRLRRFGYTNTKVLEGGILFYPNLKVMEE"
     gene            5255..6202
                     /locus_tag="PC366_003416"
     CDS             5255..6202
                     /locus_tag="PC366_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013378669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HDF2578899.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTVELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLADTQALATEIHEEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEVCPVKAAKLTDKGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQIDRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGADKFIEMLLSDEVLERKEEILEALLHLTGGAVC"
     gene            complement(6487..6750)
                     /locus_tag="PC366_003417"
     CDS             complement(6487..6750)
                     /locus_tag="PC366_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HDF2578900.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQRNYD
                     YYGGFAKKNPCRMRVPNTGTWYLVVNQDGNSGIVNFSINTIQN"
     gene            complement(6849..7094)
                     /locus_tag="PC366_003418"
     CDS             complement(6849..7094)
                     /locus_tag="PC366_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578901.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTVYKDESSDSG
                     YYALLENKEERVVWDGEVVANNIFNNLWIVVNKVKTG"
BASE COUNT         2602 a          948 c         1152 g         2500 t
ORIGIN      
        1 atatataagg agtgatgtta ttgaaaaaag atagaataac tttttcagaa attttaatat
       61 taattgtagg ctgtatatta atggccattt ctcttaattt attttttaat ccacatgcaa
      121 tcgctgctgg tggtataaca ggacttggag ttgttttaaa ttcattattc ggtgtagaac
      181 tttggattgt caatttactt ttaaatgttc cattattcat atttgcttac aaaatacttt
      241 caaaaaaaga ttgttttaaa acggttttag gaataatttt tcttaccata gcacttaagc
      301 ttactgcaaa tatggctaca ttagatataa caaatgatat gtatcttgca attatatctg
      361 gttctatttt aatgggagtt ggtcaaggac ttatttttag aataaatggc tctacaggtg
      421 gaactgattt aatggcactc ctactaaata aatattttcc tacatttagt atacctgttt
      481 taatgggtat tgtagactgc gttgtagttg ttttatcagg tatagtaaat agacaggttg
      541 aaattgcact ttattcaact gtggctttat acattttagt aaaagttagt gacttgctta
      601 ttgaaggatt taattattcc aaatcattca ctattatatc tgacctttca aaagatataa
      661 gtaaaaaaat aatggaagat ttagatagag gtgcaactat tctaaaagga gaaggtgcat
      721 atactggaga aaataaaaat gtacttttag tagtagttga aaagaaagaa gttgtcgaat
      781 taaaaaaatt agtaaaaaat gtcgacccta atgcttttat tataattaca gatatacatg
      841 aagctttagg taatggattt aaaaaaatag aataactaac aataaatagc aagtataatt
      901 aacatataca aattcaactt tttatatgtt atattatact tgctatttat atattatact
      961 ttctatttat atattataat tgttattttt aagataaaaa ttaaatgtat caattattgt
     1021 tttatacaag tatttccaaa tacgttctca tttagatagt gtgcttagaa attttagaat
     1081 tattgagtct aactttatta cttactttac tttataacaa tcaaatacaa atttaaatat
     1141 tataaaacta caaaataatt taaatcatat aatgtcaata tgtttaaatt ataaaatatt
     1201 catgtagtta tataataaat aatttataaa tatagccaac ttagcctaaa tacgtatata
     1261 atatagctaa tatggttctt atacttgata ccatcaataa aactaaaaat ataaaaagga
     1321 gaacttaaaa tgagtgttag tttacaaaaa ggacaaagag ttagcttagt aaaagataat
     1381 aatcctgtaa aaaatctagt agtaggctta ggatgggata tgaataaatt gggtaaaaaa
     1441 aattatgacc tagatgcatt tgcaatagca ttgactaacc aagataaaat gaatgttaga
     1501 ggtgacttgg tttattttgg aaatcttaaa cacccttcta aagctattat acacactgga
     1561 gataacttaa ctggaaaagg tgaaggtgat gatgaacaaa taattgttaa tttagaagac
     1621 atacctgaat atgtacataa aatagttttt ggagtttcta tatacaaagc taaaaaaaga
     1681 gaccaagatt ttggtcaaat gaacaactct tttataagat taattgattc aaattccaag
     1741 caagaattat ttaaatataa tcttcaagaa gacttttctg gtaaagtaac agttttggca
     1801 ggagaaattt atcgtagaaa tgaagaatgg aaatttaatg ctttaggaat tggtcaaaat
     1861 gaagagcttc gtgaattaat taatacatat aagtaataat tacaataaaa aatttataat
     1921 gaggagttgg tttaaatggg tataacttta gcaaaaggac aaaaagtaag tttaacaaaa
     1981 agtaaccctg gtctaaaaaa agtaatagta ggactaggat gggatattaa taaatatgat
     2041 ggtggatttg atttcgattt agatgcctct gcatttttaa ctggaactga tggaaaagta
     2101 acgaatgatg gagactttat attctataat aatttaaaac acgcttctgg agctgttgaa
     2161 tatatgggtg ataatagaac aggtgttggt gatggtgatg atgaacaaat aaatgtagac
     2221 ttatctaaaa tacctcaaaa tattgctaaa atatcattta gtgttactat aaatgaagca
     2281 attacaagaa gacaaaattt cggacaagtt gaaaattcat atataagaat atataatgaa
     2341 gaaactaacg aggaacttat taaatatgaa ttgggtgaag attttagcat agaaacagca
     2401 atagtcgtgg cagaactata tagacataat ggagagtgga aatttaatgc tttaggttct
     2461 ggatttgagg atggacttgc aggattgtgt aaaaattttg gcgttaatat aggctaatat
     2521 atctaaataa aaataagagt atattgatat actcttattt ttatttagat atattataaa
     2581 ctgtttacac ttctactctt ctttctcgct tgttttttcc catattctac tgaaatatca
     2641 aaaaatgctg aaatattttc tgtaaaaaac ttgcttctat gatatgcaat atcgaatgtt
     2701 ctatgtaagt taataccttc aatatcacaa gcccacaaaa gatgcttttt taaataatcc
     2761 tcaataagta attcggatat aactgcaatg ccaaaattat ctacaactgc tcttaatata
     2821 gcttcagagt tataacatga ccatctaata ttcattggga tttttaattc ttttaattgc
     2881 ttttctaatt gtgctcttgt accacttcct aattcacgca taattaatgg ttgatttgaa
     2941 agttctgaaa cttttataga gtctcttttg tagaactcat gcttgtgtga acatataagt
     3001 acaagattat cattaataat gctttttgta acaatatctg ggtgcttaat ttttccttct
     3061 acaatcgcaa tatctaattc actattaagt aatttttttg caatcagtct tgtatcttct
     3121 acaaatactt caggttctat aagaggattt accttgtata attctaacat tatcgggctt
     3181 attacacatg taccaacagt tactgttgcc ccaactctta tacggatatt ttttgcacaa
     3241 tgcttcatac aatcattcat ttcttcattt acagctaaaa gatgcctccc atatccaaga
     3301 agttttttcc ctgcctcagt taaatataat ttttttgaaa ttctatcaaa taacttaaca
     3361 ccatactctt tttctatttc tgaaatagct tggctaactg atgactgggt aatatacata
     3421 tttcttgcta cttcactcat tttaccacat tcagcaacct taacaaagat ttcaagacta
     3481 cgaattgtca tattatcaca accttagcaa acattagtaa atgcttatga ttttattaat
     3541 attttagtat tttacaaata tattgtcaag aagtataatt ttattataga gttataaagt
     3601 agattggagt gtgatatatt gtgaaagtat taattatagg tggagttgct gctggaacaa
     3661 aaactgctgc aaaaataaaa cgtgaaatgg gtgataattg ctctgttaca atactaaata
     3721 aaggtgatga tatttcttat gcaggttgtg gtcttccata ttacgttggt aagataattg
     3781 aagataaatc atctttaatc gtaaatacac ctgaaagttt ttctaaacta acaggagcag
     3841 aagttcgttg tggagttgaa gttacgtcta ttgatagaaa tgcaaaacaa gtaactttga
     3901 aaacgctttc aacaggagaa aaagaaaatc taagctatga caaacttgta attgctacag
     3961 gggcagaccc aataaaacca ccaatacctg gaatagattt acctggagta ttctttatgc
     4021 gtactccaaa tgatgctata aaactaagag attctattga aaacggtatt aagagagctg
     4081 ttgttattgg tggaggtttc attggtcttg aaattgctga aaatctttct gcaatgggta
     4141 tacgtgtaag tgttgttgat atggctgaac atgttatgcc tggatttgat actgattttg
     4201 ctgaatacgt tgaaaatcat atggctgata aaggcataat gatttttaca ggtgaccagg
     4261 ttgtaggtat tgaaggtgaa aataaagttg aaaaacttcg tactaaaaat agagctatta
     4321 aaacagattt agtggttatg tcagttggaa tccgtcctaa cacaggtttt ctaaaagaca
     4381 caggtttaga atttgcccct aataatacaa ttattgcaga tgaatatatg cttacaaatg
     4441 ataaagatat atacgtagtt ggagactgtg cttttgtaaa aaattcttta acaaataaac
     4501 ctacatggtc acctatgggg tcatctgcaa atcatgaggg tagaatttgc gcacaaaata
     4561 tatctggaaa atctaaaact tacaatggtg ttcttggaac gacagtagta aaattacctg
     4621 agctcaatgc aggaaaaaca ggtctaagta aagaaatagc tgaaaaagaa ggttataatg
     4681 tttgctctgt aaccatagct accgatgata aagctcatta ttatccaggt gcatctaatt
     4741 ttattataag aatggttgct gaaaaaaata ctagaaaatt attaggtgtt caagttatgg
     4801 gacctggagc ggttgataaa atagtagata tcgctgctac tgcaataact ttaggcgctg
     4861 acctttattc attagaaagt atggaccttg catatgcacc acctttttca acagctattc
     4921 acccttttgt agtggcagta aatgttttac aaaataaact taacggagaa cttgatagtg
     4981 ttttacttga cgaaattgag gattttgaca gttggactaa acttgatgtt tcaaaagctc
     5041 cttctattcc tagtttacgt tatattcctg ttggtgaaat taatggagaa attgaaggtc
     5101 ttgctaagga tgaaaaaatt cttcttatat gtgctaaagg taaaaatagc tatatggcgc
     5161 aaaatcgctt aagacgcttt ggctatacaa atacgaaagt tcttgaaggt ggaatactat
     5221 tttatccaaa tcttaaggta atggaggagt aaatatgagt aatgttacag cagaacaaaa
     5281 aaaggaagta aaaggtagag gttttctacc aagcagggat ggagaacatt ttgcagcacg
     5341 tataataact gtaaatggtg taataaatgc atcacaagca aaaaaaattg cagaagctgc
     5401 tgaaaaattc ggaaacggtc agttagcatt tactactaga ctaacagtag aattacctgg
     5461 tgtaaaattt gaagatattg aagctctaag tgaatttatt gctagcgaaa atctaataac
     5521 aggtggaact ggatcaaggg ttcgtcctgt tgtggcttgt aaaggtactg tttgtgttca
     5581 tggtctagct gatacacagg cacttgctac tgaaatacac gaagaatttt acaaaaattg
     5641 gtatgatgta aaactacctc ataagttcaa aattggtgtt ggtggatgcc ctaataactg
     5701 tattaaacct gacctaaacg atcttggaat tgttggtcaa cgtgtacctg actatgattc
     5761 agagctttgt gttggttgta aaaaatgtgc tgttgtagag gtctgtcctg ttaaagcagc
     5821 taaattaaca gataaaggta aacttgaaat agacagtaat ctatgtaata actgtggtaa
     5881 gtgtatagaa agttgtaatt ttgatagtat tgaagaaaaa gaatctggtt ataaagtcta
     5941 tataggaggg aaatggggaa aatcagttcg tcctggaaca cagattgata gattattttc
     6001 aaaagaggaa cttatgactt taattgaaaa agcaattctt ttatttagag aacagggtaa
     6061 cacaggtgaa cgttttggaa taactatcga tagaattggt gctgataaat ttatagaaat
     6121 gcttttatca gatgaagttt tggaaagaaa agaagagata ctagaggctc ttttacacct
     6181 tacaggtgga gctgtatgct aacaataaat attttaattg tacagataac ctatggaaaa
     6241 aattttagtt aagaataatt aaaattctat atatgatata tgataaatga ggctatctca
     6301 aaacacagat acgcctcttt ttcattgttg aaatgataaa gtatatttga gtttatacaa
     6361 aaaagagtgt ctcgtgaatt ataaaattca ttttgaggca cccacattat tttataataa
     6421 ttgcttatta attttatttt aactatataa aaagtacaaa aagtaagaat atccaatatt
     6481 ctaaaattaa ttttgaattg tattgattga aaagtttact attccactat ttccatcttg
     6541 atttactact agataccatg ttccagtatt aggaactctc attctacatg gatttttctt
     6601 tgcaaatcca ccatagtaat cataatttct ttgattttta aatttcacat aatttatatg
     6661 gtctaacaat attacattgg cttgtttctc taaatttacc tctacaatat cccctttttt
     6721 taagttcatc ttactataac tatattccat tgaattactc ctccagtatc gaataatctt
     6781 tgttatttac tcatctcaaa tatgtaaaaa ttcatttaaa atattacaaa tactatataa
     6841 ttagactatt atccagtttt aaccttattt actacaatcc aaaggttatt aaaaatatta
     6901 ttggcaacaa cttctccatc ccatacaact ctttcttctt tattttctaa taaagcatag
     6961 tacccagagt cagaactttc atctttatag actgtaacat aaaactcttc atcactatat
     7021 tcaggtatat ttttaaagtc ttcagatatt ttacatgtta atatataccc ttctaattct
     7081 tcatctataa acaaagcaat tcctccaatc tctatatttt tactaattat accatattat
     7141 gtcataaact ttttatttca ttacaaattt ctattttttc tttactttat aaataaatta
     7201 ta
//
LOCUS       DAMJWO010000124         7131 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.129, whole genome shotgun sequence.
ACCESSION   DAMJWO010000124 DAMJWO010000000
VERSION     DAMJWO010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7131
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.129"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            148..3327
                     /locus_tag="PC366_003419"
     CDS             148..3327
                     /locus_tag="PC366_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2578902.1"
                     /translation="MKIDMIYKLIRRNTEPSRWSRGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSKGKSIFICKHIVAIVI
                     KSLKQIKNKRDVPPILIDILGADKDKLSNTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINVDSNKAIAEFKIGIDKMYILKNITEFAYSKLNGYELDFGKKFTYNPNIHYFADED
                     EKLVDIIEEYGTNLSYNFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPVRFDFKNIEDKIVLYSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQILSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DGNICCDVKYIYDDEDKKFVLPNIQKETTIENKLTSSQFTKENNHYVFKGTDYDLFTF
                     LDLQLESLKEFGDIYYSEKFKLKKIYNASSIQASINQTNQNYLEFNFNISDINPKEYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMDKSKNNKIYKNKALYIN
                     DVIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPANLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGNKRDREKCFMELENFDVILTTYGTLRNDLEKYSEIKFDYCILDEAQNIKNPVALV
                     TESVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKMKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSMDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIIDLFN"
     gene            complement(3612..4376)
                     /locus_tag="PC366_003420"
     CDS             complement(3612..4376)
                     /locus_tag="PC366_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2578903.1"
                     /translation="MAYFNYNDKQCYYNEIGDGTPLLFLHGNTASSKMFNDIIDFYKD
                     EYKVILIDFVGHGKSQMVDKFSADLWFDEAMQVICFLEAMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWEK
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDEFVSLISSDFFENTFSLLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(4613..6106)
                     /locus_tag="PC366_003421"
     CDS             complement(4613..6106)
                     /locus_tag="PC366_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDF2578904.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLGYNIPSRVQREVIPKLLKGQNLV
                     VRSKTGSGKTVSFAIPLCENINVDCNNIQALIVVPTRELALQVKDEISDIGRLKKVRC
                     SAIFGKQSIKDQIAELKQRVHIVVATPGRILDHINKGSIKLENVKYLVIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVSLFSATIDEEIKYICEKYMLDYSVINIEENESDTNQKTR
                     QIDDKIIKANGREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKNQKFNILVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKGNSGKAITIVTEKDEKYIENIETYIGYKVNELKDIEKSRITHGKILFEEYSKG
                     ILKKVSKRKKVDKNSYKSKDIKLNIESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKYKEIPIKKKMVKVKRDIR"
     gene            complement(6431..6973)
                     /locus_tag="PC366_003422"
     CDS             complement(6431..6973)
                     /locus_tag="PC366_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDF2578905.1"
                     /translation="MKICITVGHSILKGGKSTGVNGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDVIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGT
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
BASE COUNT         2631 a         1000 c          795 g         2705 t
ORIGIN      
        1 aataaaaatc taatagtaaa ttgttattta cacatatatt gtaatagata aaagctattc
       61 atatctgcct taattttagt cttaaattta gagtgtaaat tgaatgcatt tagattataa
      121 tatatacagt gaggtaaggt gaataatatg aaaatagata tgatatataa actaataaga
      181 agaaatacag aaccatcaag atggtcaaga ggtgtaaaat attatactaa tcaattagtt
      241 gattatatag acatagatat tgatgaccta caaaataacc tgttgacatt tcgtggtgga
      301 gtcaattctg aagataatta tagcttttat tttaattcaa taactataga tataaagcac
      361 tttaagataa ttgaaaatga ttgtagttgc gctgactgtc aatcaaaggg caaaagtatt
      421 tttatatgta agcatatagt tgctattgtg ataaaaagct taaaacaaat aaaaaataaa
      481 agagatgttc ctcctattct aatagatata ttaggtgcag ataaggataa gctttctaat
      541 acaaattcta aaacaagctt agatttaagc aagcaattac tttctttgtt agacaatact
      601 aaaagagaaa gggttaattt agatgtattg ataaatgtgg attcaaataa agcaattgct
      661 gaatttaaaa taggaattga taaaatgtac attttaaaaa acattactga atttgcatat
      721 tcaaaactta atggatatga attagatttt gggaagaaat ttacttacaa ccccaacatt
      781 cattattttg ctgatgaaga tgagaagtta gtagatatta tagaagaata tgggacaaat
      841 ctttcataca acttttcttc atcacattca aaaaaattta tggagataaa tgcaagctct
      901 ttaaaacaat ttttaaatgc tattaagtac aaggatttta cccttatttt ttctaaagag
      961 gaatatcatc caaagatatt aaatgatact ctacctgtaa ggtttgattt taaaaatata
     1021 gaagataaaa tagtcttata ttctaaagat tcactacctg ttccacttac taaaaaaaat
     1081 gatgtacttt tatatgatgg caatatctat ttattatcac ataaaaaagc tcatgattat
     1141 tcaaaaatat atcaaatatt atcaaagact aaagagttaa aatttgataa agaggattct
     1201 aaggatgttt taggattgct agttcctaga ttaaaatcta tatctcaaga agttcattta
     1261 gatgataaca taaaaaataa tataacaaaa gattttaaat ctgagttcta ctttgatatg
     1321 attgatggca acatatgttg tgatgtaaag tatatatatg atgatgagga taaaaaattt
     1381 gtgctcccca acatacaaaa ggaaactact attgaaaata aacttacttc ttcacaattt
     1441 acaaaggaaa ataatcatta tgtgtttaaa ggaactgact atgacctatt tacattttta
     1501 gatttacaat tagaatctct aaaggaattt ggagatatat attattctga gaagtttaaa
     1561 ttgaaaaaaa tatataacgc ttcatcaatt caagcttcaa tcaatcagac taaccagaat
     1621 tacctagaat ttaattttaa tatatctgat ataaatccaa aagagtacaa ggatattttg
     1681 aaagcttttc aagaaaaacg tactttttat aaacttaaag atggaaactt tatagattta
     1741 tcagaaagag aaacaaaaga tttttttgaa ttagttgaaa atctagatat aatggataaa
     1801 tcaaaaaata ataaaattta taaaaataaa gctctatata taaatgatgt aatacgtagt
     1861 aaaaatttaa agtttataga tggtaaaaaa gaactagaca gtatatgtga aaaatttaga
     1921 aattttgata gcataaattt agaaattccc gcaaatttaa atgcaaacct tcgtgattat
     1981 caaataaatg gcctcaattg gtttaaagtt ttagattatt ataaatttgg tggtatatta
     2041 gctgatgaaa tgggtcttgg taaaacaata cagactattg catttttatt atcattatct
     2101 aataaaaaaa gtcttattgt tacaccgaca tcactcattt ataattggaa aaatgaattt
     2161 gaaaagtttg ctccagatat aaaagtttta ttgatacatg ggaataaaag agatagagaa
     2221 aaatgtttta tggaattaga aaattttgat gtaatactta caacatatgg tactcttaga
     2281 aatgatttag aaaaatatag tgaaataaag tttgattatt gtatattaga tgaagctcaa
     2341 aatataaaaa atccagtagc tttagtaact gagtctgtaa aaagtataaa tgcagaaaat
     2401 aaatttgcac tcactggtac acctatggaa aataatctac tagaattatg gtctatattt
     2461 gattttataa tgcctggcta tctatatagt aaagcaaagt ttcaggaatt gtttataaat
     2521 aaagaggata atgttaaaaa cctgaaaaaa ttaataaaac cttttattct tagaagaagt
     2581 aaaaaacaag ttatgaaaga acttccagat aagattgaaa aaaacttttt tgttgaattg
     2641 aataaagagc agaaaaagat atatagtgta tattcaaaag atatacaaga taaaatgaaa
     2701 gataaaaatc taaagaaaga taaaatagtt atattttctt atttaactaa actaagacaa
     2761 ctttgtttag acccaagtat agtagtaaaa gattacaata aaaaaagttc aaaaattgaa
     2821 acatgtttag aaatacttag ggatagtata aacgaaaacc acaaaatatt attgttttca
     2881 caatttactt ctgtgcttaa gaacataagt aaggaacttg ataagtataa aattaaatac
     2941 cattatatag atggtaaaac taatgccaaa gaaagacttg aacttgtaga tgagttcaat
     3001 aatagtatgg ataaaaaagt ttttttaata tctttaaaag caggcggaac tggtttaaat
     3061 cttacatctg ctgacatggt aattcacttt gacccatggt ggaatccatc agtagaaaat
     3121 caagctagtg atagagctca tagatttggt caaaaaaatt cagtacaagt tataaaattg
     3181 attgctaaag ggactataga agaaaaaata ataaaattac aagaaagtaa aaaagagctt
     3241 ataaatcaat ttataaatgg agaactttct aatgaaggtg tattaaaaag tctatctgat
     3301 gaagagataa tagacttatt taactaaatt atttaatcct acagcttaac tatataaatt
     3361 tattctaaca tttatatagt taagctacaa tatctgaata aataaaattt catattgtta
     3421 tttaatccca actttacaat ctaatgatat ctctttctat acatattgca tatacaaatg
     3481 taataacttg actattagaa tattttgttt taacaatcct atttcatcat aataatgaag
     3541 tatatgtaca ctcacttttg taagttttgc aatccatttt acagttttca ttattgtaaa
     3601 ttttggttaa attattcctc taaaaatttc tttgctacat ttgaaaaatc taatccattc
     3661 gataaaattg caggatgacc acctttatca aacaaataca ttttaccatt tttaatcttt
     3721 tcaagaagta atgaaaaagt attttcaaaa aaatcactag atattagaga tacaaactca
     3781 tcttctctac ttcctgttaa aagcacctct ggttgcatag tttctagagg cttatgaaaa
     3841 aattttccta tagttttata atgttcaaaa atagcttctg tatcattatc tacaactttt
     3901 tcccagtttt ctccttgatt ataaatataa aaagcttttg caccatcatc ttgctttgat
     3961 gcctcacgct ctattttaac attttgtaca aatgactcta aaggaacttc tccttcaaaa
     4021 ctatctgcaa ttaccttatt cactaaatca ggtctctcaa gtgcaacatt taatgcaaca
     4081 agagctcctc cactactacc aattatgttt acttttttat agttcattgc ttctaaaaaa
     4141 catatcactt gcatagcctc atcaaaccat aagtcagcag aaaatttatc gaccatttga
     4201 gattttccat gacctacaaa atcaattaat attactttat attcatcttt ataaaaatcg
     4261 attatatcat taaacatttt ggaagaggct gtatttccat gtaaaaaaag taatggtgta
     4321 ccatccccaa tttcattata gtagcactgt ttgtcgttat agttaaaata tgccatatat
     4381 tacctccttt aatatcccta taggtatata tttattactt atatttaaaa tgactattgt
     4441 cataaacatt taaaaatagt atagcttaga atgtagataa agtcaacatt cctttcctta
     4501 acaacttcta ttgttttttg aaacttcatt tcgataacag aataattcat aaatattgat
     4561 actcttactt aaatatatga tttcatcatc agagagagca gtaataacta aattatcgta
     4621 tatctctttt cactttaacc atttttttct ttataggtat ctccttatat ttttttaata
     4681 tcaaatctcc cttataattt aatatatcta catatgaaca taaatcttga acttcaatta
     4741 cacctatatc atcattagtt atacctttta tattactaaa tgcaccaact atatctaaaa
     4801 ctcttatttt cttcttctta ccagcattta aatataattt aacaacttca ctttctatat
     4861 ttagttttat atctttactt ttgtaagaat ttttatcaac tttttttctc tttgatactt
     4921 tttttaggat tccttttgaa tattcttcaa acaaaatttt gccatgtgta attctacttt
     4981 tttctatatc ttttaattca tttactttat atcctatata cgtttctata ttctctatat
     5041 atttttcatc cttttcagtt actatagtaa ttgcctttcc actatttcct tttctcccag
     5101 ttctacctat tctatgtata tagttttctt tatcttgtgg cacatcataa tttattacta
     5161 aagaaatatc atcaatatgt attcctctgg acgctacatc actactaact aatatattaa
     5221 atttttggtt tttaaaatcc ttaattacaa aaattcttct ttcttgtgat aaatctgcat
     5281 gtaactctct tattaaaaaa ccctctttac tcatcttatt atataattta gatactttct
     5341 ctttggtatt acaaaatatt atcacactct ttggattttc gctgtatatt aattctttta
     5401 aaaggatgta cttctctctt ccatttgcct tgattatttt gtcatctatt tgtcttgttt
     5461 tttgattagt atcgctctca ttttcttcta tatttataac actgtaatct agcatatatt
     5521 tttcacatat atattttatc tcttcatcta ttgtagctga aaaaagactt actattttct
     5581 ccttaggtaa atttaataat attttttcca tttgttcaac aaaaccttta ttaaacattt
     5641 tatctgcctc atctattact aaatacttta cattttccaa cttaatagaa cctttattta
     5701 tatggtcaag tattctgcct ggagtagcta caacaatatg aaccctttgt ttcaattcag
     5761 ctatttggtc ttttatagat tgtttgccaa atatagcact acatctcacc ttctttagtc
     5821 tccctatatc tgatatctca tcttttactt gcaaggctaa ttctcttgtt ggaaccacta
     5881 taagagcttg aatattattg caatctacat ttatattctc gcataaaggt attgcaaaac
     5941 ttactgtctt tccacttcct gtttttgacc taactactaa gttttgacct tttaataatt
     6001 ttggaataac ttctctttgt actctagaag gtatattata tcctaaactc ttcaatgact
     6061 taagtatctt ttcatttaac ttaaattttt caaatgtata tttcatatat taccacctta
     6121 ttatatttat cttatctata tatttttcta cattatatta ttataataca aggttctact
     6181 atttttatat tatttattag actgaagata aaaatatata ctctataaac ctatagttta
     6241 gtagcaaatc aattaaattt ttatatttaa atacctcctt aaatatactg ataaatcaat
     6301 atttaggagg tatctcttgt caataatcaa actaatctat attttgaaag tttaaattat
     6361 actaatacat tgtattttta tttatatcta atattaaaag gtattaatca atacctaaat
     6421 caccataatc tcacatattt atatctttat tcaatatacc ttctgtaatc aatcgtgcta
     6481 tataatcata acctgattca tttgctttgt tacaatcatt cacattatca cagaaaaaac
     6541 tttcaatctg tattgcaact ggatttgtat ttctcaatat atataaattt tctctttttt
     6601 tagctcctct attttcaaat aattctccaa gtctattaga tactctttta gcatattcta
     6661 atccttcagt gccatagtaa agcacttctg taccacattg tgttccatca gctttattta
     6721 aatgtagctc tactaataaa tcgtatttac cactgtttac ttttggaact ctatagaaaa
     6781 attcttctct ttctgacata aagtgccttt ctggacaaat tattacatct actgtattac
     6841 cttgacttat aagcatctca gctaacatag gagctaattt tttattataa ttgtattcat
     6901 caactatacc atttacacct gtacttttac caccttttag tatactatga cctactgtta
     6961 tgcatatttt catttacttt tttcaccttc ttttaagcca atttttatat aatagtaata
     7021 taattttaaa gttattacta ataataatat attaattgaa gaaggtaaaa gttctccgtg
     7081 attatcattt ttttaacata tttgtcttat tttatcataa gtctatattt t
//
LOCUS       DAMJWO010000125         6949 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.130, whole genome shotgun sequence.
ACCESSION   DAMJWO010000125 DAMJWO010000000
VERSION     DAMJWO010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6949
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.130"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            94..1350
                     /locus_tag="PC366_003423"
     CDS             94..1350
                     /locus_tag="PC366_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003362983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDF2578906.1"
                     /translation="MRDLNVSEYLFVFSLFSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMISILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILEN
                     IKDRYNNYNFTIINTDSLTGGKGKSNALNIGYKVSKGDFIAVYDADNTPDKNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIEGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTTVIISDILCVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIENIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            1373..3454
                     /locus_tag="PC366_003424"
     CDS             1373..3454
                     /locus_tag="PC366_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HDF2578907.1"
                     /translation="MKKFIISIISLVLFFSNISLIYKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEEVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKIKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKVENSINEYPYPYAEIENNHKLDTTIVVPDNMTRGETTAVFNLASSFGKITKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSIKEQTLLSSNCIIKQVDSPYNKN
                     KKMMVVIGSNEDDLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIILNLRYSDNLDFEKSLVTVSIN
                     DVIVGSKKLDRSHSNNDKLELKIPKDIDNKNYYQVKLTFNLSIKNSNCVTRESNNPWA
                     YVSNNSYLALSTKENETLSFENYPYPFVRDDEFNDLTVIMPDYSGSQAMTWMFRLGVT
                     LGTNINSHNGNINVIRGKEFSDKYKDTNIVVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FISNDKISFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEVEDLAYNLKPKKEVKDSSWNMSINKTTKVFLMISFITIIVVMIL
                     SMLYIKKYKRR"
     gene            3491..4576
                     /locus_tag="PC366_003425"
     CDS             3491..4576
                     /locus_tag="PC366_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDF2578908.1"
                     /translation="MRKYMNKFKLKRSILISLIILIFIFIVYFVSIELKDGSLVNNQY
                     KGKIKSANLSVDYEINQVMKDIDKLGLNTVNVPIIINVESINSDIMSIDNNSKEKAIK
                     LIKKLNKKGISTILEAYPWVENGKLYETDWNPINKKRFFYTWQNAILNELIIDVANPL
                     DVNVLNIGSNFVHLEEYQQNWGEIIDFVQSKFDGLVTYRTNWWYTKKDDSSSKLFYEQ
                     KLNNNFFDKLDFISIAAYFELSNKPVNTVDELISALHSSTVNNRGQNIKQEIYNLYKA
                     HRKPIFFGELGFSNRESASSQPWNHTPSKAVNGEEQARCFEAYKKVFENEDWINGFSV
                     FCVGKIDDEKNFYPSKESIKVIKSWYE"
     gene            4630..5754
                     /gene="wecB"
                     /locus_tag="PC366_003426"
     CDS             4630..5754
                     /gene="wecB"
                     /locus_tag="PC366_003426"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HDF2578909.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHRE
                     MLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTT
                     LATSLTAFYNKALVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLI
                     SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKN
                     IFRAIKRIVDDFEDVQIVYPIHLNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGIQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDL
                     LINKDSYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            5832..6806
                     /locus_tag="PC366_003427"
     CDS             5832..6806
                     /locus_tag="PC366_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDF2578910.1"
                     /translation="MARKLIKNLGKSKSVKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNDKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSVTIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQALENAGYSTAEDKKGNRIYAELLIDIIRSYNLQLIDNKVETK"
BASE COUNT         2897 a          650 c         1157 g         2245 t
ORIGIN      
        1 tttatatatt ttaagagaat agataaaaag aaatttttaa aataaatgat tttatattag
       61 aatcaatatt ttaaaatatt ttaggagaaa tttatgagag atttaaatgt atcagagtat
      121 ttgttcgtat ttagtctgtt tagtatatgg tctttattgc ttataaatat tattttagct
      181 atgggtggat atatatttta ttttaaaaac tttgataaag aaataaaaga aattgatgaa
      241 tatcctatga tatcaatact tgttcctgct cataatgaag ctaaagtgat aggtagaact
      301 gtggagtctt tgttattact caattatcct aagagtaaga tggaacttat tgttataaat
      361 gacaattctt ctgataatag taaagaaatt ttagaaaata taaaggatag gtacaacaat
      421 tataatttca ctataataaa tacagatagt ttaacaggtg gaaaaggaaa gtctaatgca
      481 ttaaatattg gatataaggt ttcaaaagga gattttatag ctgtttatga tgcagataac
      541 acaccagata aaaatgcact tagatatcta gtacaaacta tagtaatgaa tgatgaatta
      601 ggtgctgtta ttgggaaatt taggactcga aataaaaata aaaacctatt aaccaaattt
      661 ataaacatag aaacattaag ctttcaatgg atgtcacaag ctggtagatg gcaacttttt
      721 aatctatgta caataccagg aactaacttt atattgagga gaagtatcat agaagaaatt
      781 gaaggatggg atagtaaagc aattgcagaa gatacagaaa taagttttag gatatataaa
      841 ttgggataca agataaagct tgtaccacaa tctataacat gggaacaaga gccagaaact
      901 gttaaggtgt ggataaagca acgtactaga tgggcaaaag ggaatatata tgtattaatg
      961 aaatatataa aaaatatatt taaacaggga agaaataaga ttgtgtttga tatagcttac
     1021 tttttttctg tatattttct atttttaaca actgtaatta tatccgatat tttatgtgtt
     1081 ttaagtatat ctaaactagt agaaatttct attccaatta acttttttct aatatggata
     1141 ctatcttatc ttttatttat tatagaagtg agtataagcc ttactataga aaaaggtgaa
     1201 gcaacaattg aaaatatatt catagttgca ataatgtatt ttacatactc tcaactatgg
     1261 ctgtttgtag ctataaaagg gatgatagag tatctaaaag atataatttt taaaagagag
     1321 gttaaatggt ataaaacaga aagattttga ttcatgtaca ggaggaatta acatgaaaaa
     1381 atttattata tcaattatat ctttagtatt gtttttttca aatatatcac ttatatacaa
     1441 agtaaatgct gatgagacta aagttaaaaa ttataagttt gaaagagata taactattga
     1501 tggtgttata ggaagtaata gtactttttt tgaagtaaat aaaaattggg atattgaaga
     1561 agttttattg catcttaatt ttagtaagag ccaaatatta aatggagatg tttcaagttt
     1621 aactgtattg ataaataatg taccaataaa atctattaaa ttaaatgcta agacaaatta
     1681 taaaaataca ttagaagtat tagttccaaa agattatata attcaaggat ataatgaaat
     1741 aaaaataaaa acatacaaaa caatatctga taaaatttgc caagatgatt ccaatactgg
     1801 gaactggatg gttattcaca aagaatcata tatatcaatt agatataagc agaaaaaggt
     1861 ggaaaactca ataaatgaat atccgtatcc atatgcagaa attgaaaata atcataaatt
     1921 agatacaact atagtagtac cagataatat gactagagga gagactacag cagtgtttaa
     1981 tttggcatca tcatttggaa aaataacaaa aaatgatgat ttaaagttag atgttaaatt
     2041 atattcagaa atgaaaaatt ggtcagatga taatattata tatattggta aacctgaaaa
     2101 tacagcagaa gaaattttgg atattttaag tataaaggaa caaaccctat tatcttcaaa
     2161 ctgtataatc aagcaagtag attcaccata caataagaat aagaagatga tggtggtaat
     2221 tggtagtaat gaagatgatt taataaaggc atcaaattta ttaatagaaa atagactttc
     2281 taaccaagtt ttatcatcat cagtgcttgt aaacaaagag actaatataa aaattaatag
     2341 ggaacaaaaa ttaaatttag gtcatttaac attaaaagac ttaggatatt ctgacttttt
     2401 gttggaagga gcatttaatc aacaagcttt gtttgatgtc aaaataccaa cgggtaaggt
     2461 attagatgat ggttcaaaga ttatcttaaa tttaagatat tctgacaatt tagattttga
     2521 aaaatcttta gttacagtgt ctataaatga tgttattgtg ggaagtaaaa aattggatag
     2581 gtcacattct aataatgata agttagaatt aaaaatacct aaagatatag ataataaaaa
     2641 ctattatcaa gttaaattga catttaattt gagtataaaa aattcgaatt gtgttactag
     2701 agagagtaat aatccttggg catatgtatc aaataattct tatttggcgt tatctacgaa
     2761 agaaaatgaa accttatctt ttgaaaatta tccgtatcca tttgttagag atgatgagtt
     2821 taatgattta actgtgataa tgccagatta ttcagggtca caagctatga cctggatgtt
     2881 tagattaggt gttactttag gtacgaatat aaattcacat aatggaaata taaatgtaat
     2941 tagaggaaaa gaatttagtg acaagtataa ggatactaat attgtagttt ttggagtgcc
     3001 acataataat tctgttataa agatgttaaa taataattta aatataaagt tcgataaaaa
     3061 ttactccaat tttatatcaa atgataagat aagctttatt gatgattatg gaaaaaatat
     3121 ttctaccatt caattaataa aatcaccata taataatcaa aaaaatatca tggtaattag
     3181 ttcaatgaat gaaaaaaact tatatttagg aatggattat ttgttgaata aaagtaaagt
     3241 taatgattta aaaggagata cattgataat tgatgaatac ggagaggtag aagatttagc
     3301 ttataattta aaacctaaga aagaagtaaa agattcaagc tggaatatga gtataaataa
     3361 gacaactaaa gtatttttaa tgatttcttt tattactata attgtagtca tgatattatc
     3421 aatgctatat ataaaaaaat ataaaagaag ataatatgat aaatttatta ttttaaaaga
     3481 ggtatataat ttgaggaaat atatgaataa atttaaatta aaaagaagca ttttaatctc
     3541 attaataatc ttaattttta tatttatagt gtactttgta agtattgagt taaaagatgg
     3601 gagtctagta aataatcaat ataaaggtaa gattaaatcg gccaatttat ctgtagatta
     3661 tgaaataaat caagttatga aggatataga taaattggga ttgaatacag taaatgtacc
     3721 tataattata aatgtagagt ccattaattc tgatattatg tcaatagata ataatagtaa
     3781 agaaaaggca attaagttaa taaaaaaatt aaataaaaaa ggtatttcaa caatattaga
     3841 ggcatatcca tgggttgaaa atggaaaatt gtatgagact gactggaacc ctataaataa
     3901 aaaaagattt ttttatactt ggcaaaatgc catattaaat gaacttataa ttgatgtagc
     3961 aaatccactg gatgtaaatg ttttaaatat tggttctaat tttgtacatt tggaagaata
     4021 tcaacaaaat tggggtgaaa taatagattt tgtacaatcc aaatttgatg gtcttgtaac
     4081 gtacagaact aattggtggt atacaaaaaa agatgattca agtagtaagt tgttttatga
     4141 acaaaaattg aacaataatt tttttgataa gttagatttt atatctatag cagcatattt
     4201 tgagttaagt aataaacctg ttaatacagt ggatgaatta atttctgcct tacactcatc
     4261 tactgtaaac aatagaggac aaaatataaa acaagaaata tataaccttt ataaagctca
     4321 tagaaaacct atattttttg gagaattagg tttttcaaat agagaaagtg caagttctca
     4381 gccgtggaat catactcctt caaaagctgt aaatggcgaa gaacaagcaa ggtgttttga
     4441 ggcatataag aaagtttttg aaaatgaaga ctggataaat ggtttttctg tgttttgtgt
     4501 aggtaaaata gatgacgaaa aaaattttta cccatcaaaa gagagtataa aagttattaa
     4561 gtcttggtat gaataatttt aaaagtgtag aatttatata gattaaatag atgattagga
     4621 gagatataaa tgaatgacat caaggttatg actgtatttg gaactagacc tgaagctatc
     4681 aaagtagcac ctttaataaa ggaacttgaa aaaagagaga atataaaaag tattgtttgc
     4741 gttacagctc aacatagaga aatgcttgac caagttatag aaaccttcaa tataaatgta
     4801 gactatgatt tggatataat ggaaaaagga caaagcctga atgatataac atgtaagatt
     4861 ttaaataaac ttcccttgat tttaaacaag gaaaatccaa atataatatt ggtacatgga
     4921 gatacaacca caactctagc tacaagtttg actgcatttt ataataaagc tcttgttggt
     4981 catatagaag ctgggcttag aacctatgat aaatattctc cttttccaga ggagttaaat
     5041 agacaactta caggtattat tgctgatatg cactttgctc ctactaattt ggctagaaaa
     5101 aacttgattt ctgaaggaaa acctaataat aatatatttg taactggtaa tactgctatt
     5161 gatgctttaa agatgacaat aaaagaaaac tataatcatc ctataattga tgagattggt
     5221 aacgatagga tgattttgtt aacctctcac agaagagaaa atttgggtaa acctatgaaa
     5281 aatatattca gagctataaa gcgaatagta gatgattttg aagatgtaca gatagtatat
     5341 cccatacatt taaatcctaa aatacgaact atagctgatg agatatttgg aaaatttcct
     5401 gaaaaaattc atattataga gcctttagat gtagctgatt ttcataactt tttaaataaa
     5461 tcttatatga taatgactga tagtggagga atacaggaag aagctccatc attaggtaag
     5521 ccagtccttg tgttgcgtga taaaacagaa agaacagaag gaattgaagc aaagacactt
     5581 aaattagtag gtactaatga agatagaata tataattcag tgagcgattt attaataaat
     5641 aaagatagct atgttcagat gagtaaagca tctaatccat atggagatgg aaatgcaagc
     5701 aaatatatag tggatataat aattaaaaaa tttaattgca aatatttaaa ttagataagg
     5761 tctaaaacat taactaattg atataagatt tatgataata ttaaggaata caatttttaa
     5821 gggggagtaa tatggctaga aaattaataa aaaatttagg taaaagtaaa agtgtaaaga
     5881 gagtgaaact tttatttaag aagattttta ttactgtatt catagtagca agtatagttg
     5941 ctatttttaa tataacgaaa tattttgagg aattatacaa agtaagggat ttaaaaagta
     6001 ctaaaattga atactatatg gatgtggctg atgaagcagg agatggaaag gtccaattaa
     6061 gttggaaggc cttacttgct atagacatgg taatacatga tgaagattta agtaatataa
     6121 aaaagaaaga cacattggat ataggggaaa agtttatagt agaagataaa aatgataaag
     6181 gcgaaaaggt gtataaggta aaaaagttta ataaggtatt aagcgaattg aaatttgact
     6241 cttctcaaaa aagtagagca agaaaataca tgaaagattt ggaatacaca taccttggaa
     6301 ataaacaatt agatagtagt gatgaaaaaa ttaaatttat aaagaagtta gaagactcag
     6361 ctataagaga atatattgat tatggaatat tgccctctgt aacaattgga caagctatat
     6421 tagaatctgg ctggggaaat tctaaactta caaaacagag taataattta tttggtataa
     6481 aagcagataa agcatggaaa ggaaaaagtg tagaaatttc aacttcagag cattataatg
     6541 aaaaaattgt agctagtttt aggtcgtata attcattaca agattctgtc aaagaccaca
     6601 gtttattttt aattaataat aaaagatata gaaaacatgg gttgtttgag gcaaaagatt
     6661 atattagtca agctcaagca ttagaaaatg caggatatag tacagcagaa gataaaaaag
     6721 gaaatcgtat atatgcagag ctattaatag atattattag gagttataat ttgcaattga
     6781 tagacaataa agttgagaca aaataattgt taactttata tgaggagata acaagataag
     6841 attcttttct acaaaaagaa tagaaaaatt gtaaaaaaaa ctaaaaaaat gtattgactt
     6901 gttatttaaa aggtgatatt attattactg tactcgaaag agaacaaaa
//
LOCUS       DAMJWO010000126         6776 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.131, whole genome shotgun sequence.
ACCESSION   DAMJWO010000126 DAMJWO010000000
VERSION     DAMJWO010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6776
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.131"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(96..704)
                     /locus_tag="PC366_003428"
     CDS             complement(96..704)
                     /locus_tag="PC366_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HDF2578911.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
                     FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(813..3551)
                     /locus_tag="PC366_003429"
     CDS             complement(813..3551)
                     /locus_tag="PC366_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HDF2578912.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNINLYTVSINMYRIILLW
                     IFGYSIVYISSFKTDEFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMST
                     FIYLTISKVKKLRISPILIFYSAFVILDYFIRNIFSDINWNMIIILINICISMFNLLY
                     LLNKLDSNIEHYKLIKDLTYFVFFTTIICFVAISKINIVDSDRLIGVIYLLLCNHTYY
                     VYVYSLNNRVVYPYYELDSINKKLSKKSEQLGKINLAIEKDMIIQRTLKNYIDQRKEL
                     LRQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMNNYYKILTFIKEDEKVAEKLKK
                     FDNDISIIDKLVELNDKIYLLSLSNNKDESNYLISLNDITNEIKIDEEIRNINKDYEN
                     IILNIPSPILVRSAEGGIKKNKVISINKKYEKSFKCVSSDLVDMTLEQYFETFNIDFF
                     DNRKFKRLNLTQEKKAEIVSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFK
                     LLTFRDITKEINILRTVNEQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRAFRELFGI
                     SSDVLGVTTQKYRNILVKKYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKR
                     SRVRIIKDLSVQRESERLKKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLIE
                     NLYKKGKIIDFQDILKEHIKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIID
                     ITERIVTSISSYAKSKGIDLIFDTDEETVMVGLDPESIERIILNILSNAIKFTLEGGE
                     ILVGIYKKDETVEIIIKDTGVGIDKEKLNDIFNRFKQIENSGISNEFGSGIGLCLTKS
                     LIEIQNGKIYIDSKVGEGTNVKVIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
     gene            complement(3699..4490)
                     /locus_tag="PC366_003430"
     CDS             complement(3699..4490)
                     /locus_tag="PC366_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2578913.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKSLDELKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIVIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(4526..5182)
                     /locus_tag="PC366_003431"
     CDS             complement(4526..5182)
                     /locus_tag="PC366_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2578914.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSTINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALIILVQIIQGVGNLAYKKLK
                     "
     gene            complement(5175..6140)
                     /locus_tag="PC366_003432"
     CDS             complement(5175..6140)
                     /locus_tag="PC366_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HDF2578915.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGSVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERKTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKKLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISDKSGEHVKQYLTSKGIRWEEMINE"
     regulatory      complement(6246..6352)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
BASE COUNT         2163 a         1145 c          617 g         2851 t
ORIGIN      
        1 aagttatttt tatcaaacta aaaattctat aaaaaaataa gatacatacc tataaaatac
       61 cttcctatag atacatatct tacctatata aaaacttatt ctatataaaa acgccataaa
      121 aaatcttttg cttcttctgc ataatctata tttatacgtt tactagtttt tatatctaac
      181 tcatctttac taaatacttt ttttccttta tcatcataat aaaaatcact tatatataat
      241 tcttcaccca ttatactctt actatttaga cttctatcta tttttaaagc tttgcaaagt
      301 tttcctggtc cgttagtaat attttttact tgatatttac tcaactcagt gtaagctttg
      361 ttgtatctat tcatagatat ctcatctaaa gaagttatag gctctacccc tcttattaat
      421 acacactctg gcacattttc tatatttgca gataaattta agcaattata cataccataa
      481 attaaataaa catatatatg tccaccatct aaatataatg gcttagttct atctgtcttt
      541 ttattgccat atacatgtgc tcctttatca tttacaccca tgtatgcttc tgtctctatg
      601 attttggtaa caattacttt attttcatat ttccttatta gatatttacc taatattgat
      661 ttggctaaat caattccatt ttttctaaaa aaatcctttt ccaaaatttc acctcataaa
      721 atttatttaa aacgcatcaa atacaactaa agtaataaat aaaattaact cttattaatg
      781 tgatatatat aaacaataaa tttagccatt tattatttat atatatcaaa aaattctatc
      841 tcaaactttt caatattatc attgtaattt gaattatcat atacttcttc aacaacctct
      901 ttaattggga atataacttt tacattagtt ccttctccta ccttactatc tatgtaaatc
      961 ttcccatttt gaatttcaat caatgatttt gtaaggcata aacctatacc acttccaaat
     1021 tcatttgata taccactgtt ttcaatttgt ttaaatcgat taaatatatc atttaatttt
     1081 tctttgtcta tgcccactcc agtatctttt ataattatct ctactgtttc gtctttttta
     1141 tatataccta caaggatttc tcctccttct aaagtaaatt ttatagcatt tgataatata
     1201 tttagtatta ttctttctat agattctggg tcaagcccta ccataacagt ttcttcatcc
     1261 gtatcaaaaa ttaaatctat tcctttagac ttagcataac tactaataga tgtaactatt
     1321 ctttctgtta tgtcaataat atcaaaatta actgctttaa tcttatatat gtctgactta
     1381 acttgagaaa tatttattat attatctatt aatctcaata atctaaacat attttgttta
     1441 gttattttta tatgttcttt tagtatatcc tgaaaatcaa ttatttttcc ttttttataa
     1501 aggttttcaa taagttgaac tgaactatat atattattta aaggtgtctt aagttcatga
     1561 gatatattag cataaaactc catcttcatt tggtcatact gtctttgttt tattaatgct
     1621 tttttaagtc tttcagactc tctttgcaca cttaaatctt taataattct cactctactt
     1681 cttttctgtc caaagtataa tgttcttgat atcattttta cttctttaat gtgattattt
     1741 tcatttacta tatggatact cttctctctt tctcctatat ttaaattgtt tatgtatttt
     1801 tttactaata tatttctata tttttgtgtt gtaactccta atacatcact agaaattccg
     1861 aacaactctc taaaggctct atttgtatat agtactcttg atgtacttaa atcctcaaga
     1921 aaaatagcct ctggtataac atcaagtaat ttttcatata ttattttttg ttcatttact
     1981 gttctaagaa tatttatctc tttagttata tctctaaatg taagcaattt aaagagttta
     2041 ttatctgacc aatagtctcc aactctaact tcttcaacat gttcttcacc ttctgagtca
     2101 gacatcacaa aattaactat acagtttgct gtgtcattgt aacttactat ttcagctttc
     2161 ttttcttgtg ttagatttaa tcttttaaat ttcctattgt caaagaaatc tatgttaaaa
     2221 gtttcaaaat attgttctaa tgtcatatcg actaaatcac ttgaaacaca tttaaaactc
     2281 ttttcatatt ttttatttat acttattacc ttattcttct ttatgccacc ttcagcactt
     2341 cttacaagta taggagatgg aatatttagt ataatgtttt catagtcttt atttatattt
     2401 cttatttctt catctatttt gatttcattt gtaatatcat ttaaacttat taagtaattg
     2461 ctttcatctt tattattact taaacttaac aaataaattt tatcatttaa ctctaccagt
     2521 ttatcaatta tacttatatc gttatcaaat ttcttcaatt tttcagcaac tttttcatct
     2581 tcctttataa aagttaatat tttataataa ttattcatat cctttgaaaa ttcatcttta
     2641 aatttattat ttgtgtaact tatattaaaa tcatagtctg ttactatcca tacatttggt
     2701 attgtatcca gagcttgtct aagtaattct tttctctggt ctatgtagtt ttttaatgtt
     2761 ctttgtataa tcatatcctt ttctattgct aaatttatct ttcctaattg ctctgacttt
     2821 ttacttaatt ttttattgat tgaatcaagt tcataatatg gatacactac tctattatta
     2881 agactgtata catatacata ataagtatgg ttacataata gtaaatatat tactcctatt
     2941 aatctatctg aatctactat attaatctta gaaattgcta caaaacatat aatagttgta
     3001 aaaaaaacaa aatatgttaa atcttttatt aacttatagt gctcaatgtt actatcaagt
     3061 ttattcaaca aatatagtaa attaaacata gatatacaaa tattaattaa tataataatc
     3121 atattccagt taatatcact aaaaatattt cttataaagt aatctaatat cacaaaagca
     3181 ctataaaaaa ttagtattgg gcttattctt agttttttta ctttagaaat ggttaagtat
     3241 ataaaagtag acatattaat tatgcttaag ttaagcaata caatttggaa tttttgaatt
     3301 tttaaattta ctactcctaa aatacttaca aaaactaata caagacaccc tactttcaat
     3361 atatttataa attcatctgt tttaaagcta cttatataaa ctatagaata tccaaatatc
     3421 caaagtaaaa ttattctata catatttata gaaactgtat acaaatttat atttaaaagt
     3481 gcaataacca aaaataaccc attagctagt atatagacct tattcttact taaagttcct
     3541 ttagattcca tattccccac cacttcttca tttttatata gttttaccta taaatatgtt
     3601 accacaattc ttccaaaaaa tttgtcactt tctagttata aaaaaaaatg agtaaatatt
     3661 tttaatttta ctcattttgt agattttgta tattcagttt aaaaagctgg aactatactt
     3721 cctttatatt catcttgtat aaatttttta acttctttac tattcatagc ctctgataaa
     3781 gccttaatct tatcactatc tttattattt tctctacaag ctattatatt tacatatgga
     3841 gaatcacttg attctattac tattgcatcc ttagtaggat ttaagttagc tgttaaagca
     3901 taattagaat ttattactgc tccgtcaaca tcttttaata ctgttggtaa ttgctctgca
     3961 ttcatttctt ttattactat atttttagga tttttagtta tatctttttt agttataagc
     4021 tctccatctt ttacttctat caatttattt tttgctaata atttaagtgc tctagctcca
     4081 ttagttgcat catttggcac agctataaca gctccatctt ttaattcatc taatgactta
     4141 actttttctg aatagaatcc cattggctct atatgaactt tagatgtata agtaagttta
     4201 tatcctttct ccttcacagt ttcctctaaa aatggaatat gttgaaagaa gttagcatcc
     4261 aaagaccctt catctaaagc tgtatttgga agtacataat catcaaatat ttttacttct
     4321 aaatcatatc ctttttcttt taacaaaggt tttgcaactt ccaatatctt tgcatgtgga
     4381 tttgatgaag ctcctactag tattttttta tcctctttgt ttgaacaacc tactgctgat
     4441 attgctattg ctgacaccaa tgctactgat aataatttct ttaatttcat ttttactccc
     4501 cctctttaaa atgtttataa ttaatttatt ttagtttctt ataagccaga tttcctactc
     4561 cctggattat ctgaactaat attataagtg ctattacagt atataccatt actgctgtat
     4621 caaatctttg atatccataa ataagtgcta tattacctaa tcctccagct cctactgcac
     4681 ctgccatagc tgtataacca agtatagata ttattgataa tgtaattcca gatactattg
     4741 aaggcatagc ttcctttatc ataactttaa atactatttg tctttttgta gctccaaaag
     4801 attttgctgc ttctatcaat cctttatcaa cttcatttaa tgagctttct ataattctag
     4861 cgataaacgg tgctgcccca atagttattg gcactattgc agcagtttcc cctatacttg
     4921 ttccaacgat taatctagtt attggaatca ttgcaactat aagtatcata aatgggaaac
     4981 ttctaaatat atttactata aatcctaatg cactatttat tgtgctattt ggttttaatc
     5041 catctggttt tgtaactact aatatgattg ctaatataaa tcctaatatt gttgccacta
     5101 tagttggtac tataaccata tacaaagttt gtaacaatgc atttggaaat agtgttgtta
     5161 aaaagtcaat taaactattc atttatcatt tcctcccatc ttatgccctt actagttaga
     5221 tattgtttta cgtgctctcc acttttatct gaaatgttta taataagtga acctaaaata
     5281 tcatctttaa attgttctaa tttcccaaat attatagaca catctatatt tagttctctt
     5341 gccatagtcg taataatagc ttcattagaa atatctttag ggaatagtat ctttatattt
     5401 gttccttttg gcaatattat actttcttca cctattaatt ttctaagtcc tttagtattt
     5461 cttaagaata tttcttctgt atctcctacc tctaatactt ctccattttc cattattgct
     5521 actcttccac aaatctgctt tataacttcc atttgatgag ttacaactat tattgttatt
     5581 cccaattttt tatttatatc ttcaagcaat gaaagaattg actttgtagt atttgggtct
     5641 aatgctgaag ttgcttcatc acaaagaagt acttgtgggt ttagtgctaa agctctagca
     5701 attgcaaccc tttgtttttg tccgccactt agatttctgg gtttatcatt tttcttttca
     5761 gatattccaa ctacttctaa taactctaaa actctttttt taatttctgc ctttgagtat
     5821 ccaaaacatt ctaatggcaa tgctacatta tcaaatacag tttttctttc aagcaatgaa
     5881 aagtgttgaa aaatcattcc taactctttt cttaaatctc tcatttgctt ttcattcaat
     5941 gactttactt ctttatcaga aacaagtaca ctgccttctt ggtattcttc taatccgttt
     6001 atacatctca gtagtgttga tttccctgca ccactatgac ctattattcc aaaaatttct
     6061 ccagattcta tttcaatact tacatcttta agcacttgaa tctttccata atacttatta
     6121 acatttttta tgctaatcat aaaatttcct cccatatatt ctgctcagtt tttatgttta
     6181 tcctctctta tgtattacaa caaaataaaa gcccgagtat aaactcaggc ttagaaagct
     6241 atttatactc atctatcaac tatattagtt gcaggattta gcaccaatgt atataaaata
     6301 tactggttgc cgggtttcaa agggccagtc cctccaccac tcttgataag acgttattta
     6361 attcaattct attatcattt gttgctatgt tatatatgat atattcatta atagtatttg
     6421 tcaataaatt tatttaaatt ttttattttt tattatcgtt aattaactat ttttaattag
     6481 ttttctagct cctaacactt tatattttaa tgtctatata actatagaac atcattataa
     6541 gaaataaatt aaataacatc aatctatcta aatcatctgt aaagtaaatt aagaaaatta
     6601 acattttatc caaactctat cctactatta aataaaataa tttaaataca atgatgatta
     6661 tatagctcta atactttaga ctttctgaac ctcccatgac taaagtcaca gggttcctgc
     6721 ttcatagaat tttgcatact aaaatatgtc ttactaattc tccacaggct atcccc
//
LOCUS       DAMJWO010000127         6750 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.132, whole genome shotgun sequence.
ACCESSION   DAMJWO010000127 DAMJWO010000000
VERSION     DAMJWO010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6750
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.132"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            40..282
                     /locus_tag="PC366_003433"
     CDS             40..282
                     /locus_tag="PC366_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDF2578916.1"
                     /translation="MQNSMKQEPCDFSHGRFRFKTSDNRVLIPVVIFLGSIVTALCDL
                     ISRVILSPVELPISTITSLLGAPIVVMLLVKRKDRA"
     gene            285..1481
                     /locus_tag="PC366_003434"
     CDS             285..1481
                     /locus_tag="PC366_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578917.1"
                     /translation="MLKTNNLSVGYNNKVVISNINVEVKNGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINCISRKALSKKMALVLTNRLLGDLMTVQDIVNIGRYP
                     YTGFFGSLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKKLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDEDIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFEPISDESFDLAIRNLNDSKIIIDT
                     GFSVGETNKRNIDIIKEALKLDKKVYSFRNRDESKKYYDSLDSKIEHIDKVSQIINSA
                     DINNLL"
     gene            complement(1601..2326)
                     /locus_tag="PC366_003435"
     CDS             complement(1601..2326)
                     /locus_tag="PC366_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDF2578918.1"
                     /translation="MKTISKQELEKTLEKHYLWLKNNNAGEKADLKELRLENMDLRGY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGANFRFCDLS
                     NSDIRGANLENSNLEHATLNGVISDESTPFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSIDGKESFKSARAYADENFIYRVGETIVAEDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
     gene            2804..4903
                     /gene="nrdE"
                     /locus_tag="PC366_003436"
     CDS             2804..4903
                     /gene="nrdE"
                     /locus_tag="PC366_003436"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HDF2578919.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEEFIQPKLRKFN
                     NLEERLKYLIDEGYYLKEVINQYSIDVIKNIYDMIDKHKFEFQSYMSANKFYQNYALK
                     SNDGKEILETYNDKVLIVALTLGNGDKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDEWYDKLVNDSDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIERNQT
                     FEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            4916..5887
                     /gene="nrdF"
                     /locus_tag="PC366_003437"
     CDS             4916..5887
                     /gene="nrdF"
                     /locus_tag="PC366_003437"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HDF2578920.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKVWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNLEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKKMLEEKMYSILYSLMENEIEYTNVIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            5963..6589
                     /locus_tag="PC366_003438"
     CDS             5963..6589
                     /locus_tag="PC366_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDF2578921.1"
                     /translation="MKYEWRKRDKELYLPKKNPVIIEIPEQKFIMLKGSGDPNSKEFI
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKGLDVLIKEDLIYT
                     IMIRQPDFVTQDLLDKATDIVKKKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYTHREIYISDARKVSPESLKTVLRFEVEREV"
BASE COUNT         2655 a          742 c         1175 g         2178 t
ORIGIN      
        1 ggggatggcc tgtggagaat tagtaagaca tattttagta tgcaaaattc tatgaagcag
       61 gaaccctgtg actttagtca tgggaggttc agatttaaaa catcagataa tagagttttg
      121 ataccagtag taatattttt aggcagtata gttacagctc tttgtgattt aatatcaaga
      181 gtaattttat caccagtaga attaccaata agcacgataa catctttatt aggagctcca
      241 attgtagtaa tgttattggt gaaaaggaag gatagggctt agacatgttg aaaactaata
      301 atttaagtgt aggatacaat aacaaggtag ttataagtaa tataaatgta gaagtaaaaa
      361 atggagaaat actatgtctt ttgggaagta atggagctgg aaaaactacc ctattaaggt
      421 ccttatctaa acttatatca ccaataaaag gtgaaatata tttgaatggt gtaaacataa
      481 attgtatatc aagaaaagca ttatcaaaaa aaatggcttt agtacttaca aatagattat
      541 taggtgattt aatgactgta caagatatag tcaatatagg aaggtatcca tatacaggat
      601 tttttgggag tctatctaag aaagatttaa taatggtaga tgaagcattg gagtctgtag
      661 atgccttaca tttaaagaaa agatattttg atgaactaag tgatggagaa aaacaaaagg
      721 tgttggttgc aagagctctt gttcaagaac cagaaataat tatattagat gagcctacaa
      781 ctcacttgga tataaaacat agattggagc tcataaacat actgaaaaaa ttaagtaaag
      841 aaaagtcaat atcagtaata ctttcattgc atgaaataga catagcatta aaaagttgtg
      901 ataaagttgc tcttataaaa aataataaag tcatagctta tggtcagcct gaagatgtag
      961 tagatgagga tattataaat tcgctttatg aattggatga taaaaacttt aatagtcttt
     1021 taggttcagt agaaattagt aataaatcta aaaatgaagt ttttataatt ggtggtgggg
     1081 gtaaagcaac accaatttat agagctttta ctaaaaaagg tataggtctg tattctggaa
     1141 taatacatga aaatgatatt gattatgaaa ttggtagaac tatggggata aagatgttta
     1201 cagaaaatcc atttgagccg ataagtgatg agagtttcga tttggctatt agaaatttaa
     1261 atgattccaa gattataata gatacaggat ttagtgtagg agagacaaat aagaggaata
     1321 tagatattat aaaagaggct ttaaaactgg ataaaaaagt ttattctttt agaaatagag
     1381 atgagagtaa gaagtattat gacagtttgg atagtaagat agaacatata gataaagttt
     1441 ctcaaataat caatagtgca gatataaata atttattata atttatgaaa taaaatgtac
     1501 ttatgtgcta tagaaaaaag agtatagatt ataatttttt tgaaattaca atctatactc
     1561 ttttgttatt ttgtttatat atttataaaa ctttagcatt ttatagataa ccaatagctt
     1621 cctctctagt taaaaaaaag tgaatccctg tagtcgattc tttccatcta ttttcattaa
     1681 aatcttcagc tacaatcgtt tctcctactc tatatataaa attttcatca gcatatgcac
     1741 gagcactttt aaaagattct ttaccatcta tactagtaat tgacagtact tttgccttat
     1801 cacatctaca agcatttgat gtagcagaca ctctttttgc gtcgctgggt attaataatt
     1861 gtaccattct gaaattaaaa cattttttat agcctataaa tgctcctgtt tcaggacaat
     1921 acaatttaaa aaaaggggta ctttcatctg atattactcc atttaaagta gcatgttcta
     1981 aattggaatt ttctaaatta gctcctctaa tatctgagtt agataagtca caaaatctaa
     2041 aatttgcacc acttaagtct gcatttttta atatagaatt ttttaatgaa caatccgaaa
     2101 gataagaatt attaaaaata gagttttcta aatctgcttt ttctaaattt aaattgataa
     2161 ggtcagacca cgaaaagtca atattactta agcagtatcc tcttaagtcc atattttcta
     2221 atcttaattc ttttaaatct gccttttctc cagcattatt gtttttaagc cataaataat
     2281 gtttctcaag tgttttttct aattcttgtt tagaaatagt tttcattaaa atcaccttca
     2341 taaatttatt tttatatatg tagtagcaaa atagtcatat atttaattat ataacaataa
     2401 ataaaaaact tctaaataat atataaaata tcatcttgaa agtacttttt tcaatatatc
     2461 agaatatatt tttaagctat ttagagataa tttaaatttt taaacaggac ataataagct
     2521 tgtatttttt tatatttgag ttgataaaaa tttctttaaa taaaaataat gtcaattata
     2581 aagtaataaa agtttagata taaaaaaatt tgtgtatata ctatatgtag tatataatag
     2641 ataaagcact gactatatgt agtgcttttg tttttgaaaa atacttattg catttctata
     2701 attatagatt aattttggga tttcaactga taagtaccaa aagaaataat aagcaaatta
     2761 agtgaaatta tggcacaaga ttatgttaaa aggacggtaa ataatgaatt ggatagagct
     2821 taacaatcaa gtgataatta aaaatgaaca aggtaagtac caattggaaa aggataagga
     2881 agccttaagt agttacatag aagaatttat acaaccaaag ttgagaaaat ttaataacct
     2941 agaagaaaga ttgaagtatt taatagatga aggttattat ttaaaagaag taataaatca
     3001 gtatagcata gatgttatta aaaatatata tgatatgatt gataaacata agtttgaatt
     3061 tcaatcatat atgagtgcaa ataagtttta tcaaaattat gcattaaaga gcaatgatgg
     3121 aaaggaaata ttagaaacat ataatgataa agtgttaatt gtagctttga cactaggaaa
     3181 tggcgataaa gatttagctt taaacttggc agataaaata gtaaaacaag aatttcaacc
     3241 agctacacct acttttttaa atgctggaag aaagagggct ggagaaatgg tatcatgttt
     3301 tttactatct gtagaagata gtacagaagg tatatcatat gctatatctt catcaaatca
     3361 cttatcaaag attggtggag gagttgcact aaatttatct aaacttagag catctggcga
     3421 atctatcaaa gatatagaag gtgcagctgg aggtgttgtt ggagtagcta aaatgttaga
     3481 acaatcattt agttacttta atcaaatggg agctagacaa ggttctggtg cggtgtacct
     3541 tactgtattc catcctgatt ttgaattgtt gatggatact aaaaagataa atgcagatga
     3601 aaaaataaga cttgctacat tatcattagg agctataata ccagataaat ttatggagtt
     3661 ggcagaaaaa aatgaagtag catatgcatt ttatcctcat actgtgtata agaaatatgg
     3721 agtttctctt gatgagatag aaatggatga gtggtatgat aaattggtta atgatagtga
     3781 tataagaaaa aaagaaataa atcctaggca gatgttgaca aaaatagcac aaatgcaaca
     3841 agaaagtgga tatccatatg tagtgtacat agatacagct aatagagaac atacattaaa
     3901 agatgttgga attattaaaa tgtctaactt atgttgtgag atatttcaat atcaaacacc
     3961 ttcagaaata gaggggtatg gaggaaaaaa tgaatgggga caagatataa gttgtaacct
     4021 aggttcttta aacatagcca atgtaatgga taataaaact atagaaagta cagttgaaac
     4081 agcaataaga gcactgtcat ttgtagcaga tagcacagat ataaaaccag tgccaacggt
     4141 aagcaatagt aacagcaagt ctcattctat aggattagga gctatgaatt tacatggata
     4201 cttagtaaga gaaaatattt tatatacttc agatgatgct atagattttt ctaatgtatt
     4261 ttttgcaatg gttagatact attcaattaa agcttctatg aaaatagcca tagaaagaaa
     4321 tcaaactttt gaaggatttg ataaatcaga atatgttaag ggaagaaata gcaaggtttt
     4381 atcaaaatac tatgaacaat cttatctacc taagtcagaa aaggtaagag cattatttga
     4441 agggatttat ataccaacaa aagaagattg gacaaaatta ttggatgaag taaaagaaaa
     4501 agggatatat aatgcatatt taatggcagt agcaccaact caaagcatta gttatgttca
     4561 aaatgctaca tcaagtataa tgccaattac tgagccagta gaagtaagaa catatggaga
     4621 ctctactaca atatatccaa tgccattttt aacaaatgat aatatgttgt attatcaatc
     4681 agcatacagg atggatatga gaaaggtcat agatttagtg gcaacagttc aaaaccatgt
     4741 tgaccaaggt atatcaacaa cactgtttgt tacagatgaa aagacaacta gagatatagc
     4801 tagacattac atatatgcct ataaaaaagg tttgaaaagt ttatattaca caagaacaaa
     4861 gatgacaaga gatactcatg agtgtctagt gtgttcagta tagggagaga aatatatgac
     4921 atttaattta cataaaatac ataatgcagt taactggaat agagaagaag atggatttac
     4981 acaagctttt tgggaacaaa atgtaaaaca attttggctt cctgaagaaa tatctgtttc
     5041 taaagacata aaggtatgga atgaactaag taataaagaa aaggaattat ataaaaaagt
     5101 attgggtggt ttaacattac tggatacaaa acaggggaat aatggaatac catctatgat
     5161 gagtttaaca gaaaacctac aaagaaaagc tgtcttgtct tttatgggga ctatggaaga
     5221 aatacatgca aaaagttatt cttctatatt tatgactcta ctttctaatt tagaaataga
     5281 tgaattattt gaatggatag aaacagaacc aacattacaa agaaaggctg atttagtttt
     5341 agctcaatac gaaaatacta caaatcaaga gggattatac ctatcaatgg ttacaagtgt
     5401 atttttagag agtttcttgt tttattcagg attcttttat ccattgtatc tatctggtca
     5461 aggaaagatg gtagctagtg gagaaataat atcgcttatt cttagagatg agtctttaca
     5521 tggtaagtat ataggattgc tagcacaaga aatatacgat tcatttgata aaatggataa
     5581 gaagatgtta gaagagaaga tgtattctat actttatagc cttatggaga atgagataga
     5641 gtatacaaat gttatataca gagaaagtgg gcttgaaaaa gaggttgtga actttttaaa
     5701 atacaatgcg aatagagctt tagaaaatct agggtttgag aagctatata ctgtagatgc
     5761 tataaatcca attgtattaa atggtcttag cactgaaacc aaaacacatg atttcttttc
     5821 aactaagggt aatggatacc aaaaaggagt gtatgaggaa ttagaggatg aagattttat
     5881 aatataattt ataattatga cacactgttg tcacttttag cgtgataata tcaatgtata
     5941 aaatatatat ggaggtattt ttatgaaata tgaatggaga aaaagagata aagagttata
     6001 tttacctaaa aagaatcctg taataattga aataccagaa cagaaattta tcatgttaaa
     6061 agggagtgga gacccaaatt ctaaagaatt tattgaagca ataggagtac tttattcttt
     6121 ggcatatgca ataaaaacca tgcctaaaaa aggaattgta ccagaagggt attttgacta
     6181 tacggttttt cctttagaag gtatatggga taagggagaa aaaagtaaag gcttagatgt
     6241 acttattaaa gaagatttaa tttacactat aatgatacgt cagccagatt ttgttacaca
     6301 agacctgttg gataaagcta ctgatatagt aaagaagaag aaacctcata atcttcttga
     6361 aaaagttagg tttgggtcta ttaatgaagg gctatgtgtt caaatgcttc atataggttc
     6421 atatgataat gaaccagaaa gttttgacat tatgaacgaa ttttgcaaaa aaaataaact
     6481 tataagaaaa tcttacacac atcgtgaaat ttatataagt gatgctagaa aagtatcgcc
     6541 tgaatcattg aagacggttt tacgttttga agtagaaagg gaagtataaa tattttgaat
     6601 aatttataag agttataaaa agtgaagtct gttgagactt cattttttga tgcaatttta
     6661 aaattaaatt tgatgtttca taatatttta aaaactttct acttttatta gtgtgaataa
     6721 ctgttgctat taaataataa tactaattat
//
LOCUS       DAMJWO010000128         6742 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.133, whole genome shotgun sequence.
ACCESSION   DAMJWO010000128 DAMJWO010000000
VERSION     DAMJWO010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6742
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.133"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(22..1707)
                     /locus_tag="PC366_003439"
     CDS             complement(22..1707)
                     /locus_tag="PC366_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578922.1"
                     /translation="MKYLIEIAKKERLLVFIYLALGIGIELLNSFSANYYQSLIDRFN
                     NSTINFHIIFIYGTVLVTLCLLRYIDEYPGRRLEHSFFLDLKLKALEKMSKIDYLEYQ
                     MLGTGKLIQKIENGANAGRNIFFNFLLAVVRKIIPSILFSMVFIYRIDKKVMFTILIG
                     YFIVFIITNLLIKALYQIKEHILINEEKMNHFLVRGFVEMVVFRVNKRFEYEICQSKF
                     AKKEIIDSRVKMTLIHEAFFTIFSLIVTFIKMLIIVYSWKTKTISIGSIIALITLLDN
                     AYTPIAIFNVLYIQFKLDKAAYKRYTDILELNNDGQLLAGKEVNLMYGNIEFNEISFL
                     YNNKREIFNKLSLSIKSGEKVAIVGESGSGKSTLIKLLIGLLKPSEGTIFIDDYNLLE
                     MNLNSYYNYVTYVSQDSPIFDGTLRENIVFGKTIKSNDIIEVLEKVGLKNLYLKLEAG
                     LDTKLGEKGTTLSGGEKQRLALARLWFSDAKIIILDEATSALDNITEEKVMLNVMEFL
                     KDKTTIMIAHRFNSIKNVENIIVLKEGSIIGSGSFKKLLDGNLYFRELYYTMS"
     gene            complement(2630..3211)
                     /locus_tag="PC366_003440"
     CDS             complement(2630..3211)
                     /locus_tag="PC366_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2578923.1"
                     /translation="MNNKKHWYDYLWIFSSIYLVLGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMILFKPRSWCVYCPMGTMTQMICKAKSKSV"
     gene            complement(3204..3434)
                     /locus_tag="PC366_003441"
     CDS             complement(3204..3434)
                     /locus_tag="PC366_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2578924.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            complement(4759..5034)
                     /locus_tag="PC366_003442"
     CDS             complement(4759..5034)
                     /locus_tag="PC366_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2578925.1"
                     /translation="MLELTKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELMIKLFNGKNYMELARMFEMSVINVRHIVRKK"
     gene            complement(5110..6411)
                     /locus_tag="PC366_003443"
     CDS             complement(5110..6411)
                     /locus_tag="PC366_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2578926.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLA
                     RRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKID
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
BASE COUNT         2312 a         1235 c          549 g         2646 t
ORIGIN      
        1 tttcttatac ttacataata attatgacat tgtatagtat aattctctaa aatataaatt
       61 accatctaat agttttttaa agctaccact acctattata ctcccctctt taagaacaat
      121 tatattttca acattcttaa ttgagttaaa tctgtgagca atcataatag ttgttttatc
      181 tttcaaaaat tccataacat ttagcataac tttttcctct gtaatattgt ctaaagctga
      241 tgtagcttca tctaatataa ttatcttagc atctgaaaac caaagccttg ctaatgctag
      301 cctctgcttt tctccacctg ataatgtagt tcctttttca cctaatttag tatctaaacc
      361 agcttctaat tttaagtata aattttttaa acctactttt tctaagactt caataatatc
      421 attacttttt atagtttttc caaatacaat attctcacgt aaagttccat caaatatagg
      481 tgaatcctgt gacacatatg taacataatt atagtaacta tttagattca tctcaagtag
      541 attataatca tctataaata tagttccttc gctgggcttt aataatccaa ttaatagttt
      601 aattaaagtt gatttaccag aaccactctc tccaacaata gctacttttt ctccactttt
      661 aatacttaaa ctaagtttat taaatatctc tcgcttatta ttatacaaga agctaatctc
      721 attaaattca atatttccat acattaaatt aacttcttta cctgctaaca gttgaccatc
      781 attattaagt tccaaaatat ctgtatagcg tttatatgct gctttatcta gtttaaattg
      841 aatatacaat acattaaaaa tagctatagg agtatatgca ttatctagta aagttatcaa
      901 tgcaattata gaacctatac ttattgtttt agttttccaa ctataaacta ttattaacat
      961 ttttatgaac gtcactatta atgaaaaaat cgtgaagaaa gcttcatgaa tcagtgtcat
     1021 tttaacccta gaatcaataa tttctttttt cgcaaatttt gactgacaaa tttcatactc
     1081 aaatcttttg tttacccgaa atacaaccat ttctacaaat ccacgaacta aaaaatgatt
     1141 catcttctct tcattaatta atatatgctc tttgatttga tatagagctt ttattagtaa
     1201 attagtaata ataaaaacta taaaatatcc aattaatatg gtaaacataa cttttttatc
     1261 aattctataa ataaaaacca tactaaataa aattgatgga attatttttc taacaacggc
     1321 taataaaaaa ttaaaaaata tatttctgcc agcattagct ccattttcaa ttttttgaat
     1381 taattttcca gtgcctaaca tctgatattc taagtaatct attttactca ttttttctaa
     1441 agcctttaat ttcaaatcta aaaaaaaact atgttctagt cttctacctg gatattcatc
     1501 aatatatctt aaaagacata aagtaactaa tacagttcca tagataaaaa ttatgtgaaa
     1561 atttatagta ctgttattaa atctatctat taggctctga taataattag cactaaaact
     1621 atttaaaagt tctattccta tacctagtgc taaatatata aaaactaata acctctcttt
     1681 ttttgctatt tctattaaat atttcataac tgtacaccta tccttattta ttttacttta
     1741 ttaacttaaa ataattttat agataaaatg tttctttatt tgtttaaatt tagtgtgatt
     1801 attaatcatt tcaagttaac aaaacctaaa gtttttagca gtacagttct atttgttagc
     1861 aaattattat tttactcagt acattatgct aacatataat ctaactgtac tgagtaaata
     1921 tctcgtttca tcatataaaa tctccttttt atagtttaat atatatagtt aaatttacta
     1981 tataatctga atatttattt ttctatcacc tttaccagaa ataaaatcaa ttatttattg
     2041 tataagcaaa acttcataat attttcaaca tataattatt atacagaact cctaagttaa
     2101 tttaaagtta gaatttattt ttataagaaa tgtcattgac ctacctttaa taaaacagcc
     2161 accatttttt tatgtattaa catataatat atagtaatga aaacatatta attaaaaaat
     2221 attgtataaa ttagtttatc tgtaacaaat ccagtttatg tttcaacaag cacgtaagac
     2281 ttcttgaaat ttaatctgct tcctttaaat atctattact tgttttaagc ataagtttac
     2341 aatcttctat aacatttatc atttcttcag atttctctga cgtacttaaa atacaagttg
     2401 ttacattgtt tttctattta attagtaatg tatcatgtaa aaaagaagca taaatgagtt
     2461 tactttatac aaacttcatt tatgctccac tcatatacct atcatagcta atagaaacta
     2521 ttactcatct tgaatctatt tcatatttag atatttatat ctttcttatt ttcttaaatc
     2581 aactctagct ttaaacatta aaccccttaa atcttcacaa aatctcttcc tatacagact
     2641 tactctttgc cttacatatc atctgagtca tagtacccat agggcaataa acacaccatg
     2701 aacgaggttt aaacaatatc atagtaatca aaccaagaac agttgatgta agcataacac
     2761 tataaaaacc aaatgcaaac tgtaccaccc aaggtgaaac taaagttcca tgatacgccc
     2821 attgccaagg catttttata gtccacaaca aagtcactac ttctttaaaa tttctacttc
     2881 cttcaaacac taaataagtt gaaaaaagca tattggcaaa cattaccata aaaaatgtca
     2941 aaaacccata tctaaaccac ttacttctaa taaatttagg aatatctcta tttcttgaca
     3001 gcttcaattt atttccaagc aaattaaaca gttgccctct tccacaatac ttattacagt
     3061 aagctttatt tcccttaaca atagaaatag ctagtggaac aaagaaacaa attagcccaa
     3121 tccaagcgaa aataatattt acaaatccca ataccaaata tattgaagaa aaaatccata
     3181 aatagtcata ccaatgtttt ttattattca tgacacttac cttcttcctc ttttaatatt
     3241 gttataatct caattacaga tgctggacat atcttttcac aaatcccaca tccaacacat
     3301 aaatctctat taatttttgc actaatgcca catggaactg agatagcact tcttggacat
     3361 gcttttatac agctaccaca agcaacgcac tcatttgcta aaatatttgc atacttcttt
     3421 tttttattag acataataac ctccctatat tattaatcta taagaattat atcaagatac
     3481 ttacttttta tctgtgactt aatcacataa aacctcaata ttaaaaatca cactctaaat
     3541 acaaaggagt ttcaaataaa aaacgatatg aagtcattaa gtttagcttc atatcgcctt
     3601 ttcttttgtg tatctatata aatatttatt atctaatatt taatatatct ataatatttt
     3661 cttatacagc tctataattt tacacctaat catattctat tagtaacagg ttaataccca
     3721 tctaaaacta taactttatt cacaatctta ttctattagc cacaagttaa actcatattg
     3781 aagtttatct ttagttacac tcttactcta ttaatcacaa gttaagccca tattgaagtt
     3841 tatctctatt tacactctta ctctattaat cacaagttaa gctcatattg aagtttatct
     3901 ctatttacac tcttactcta ttaaccacaa gttaaactca tattgaagtt tatctctatt
     3961 tacactctta ctctattaat cacaagttaa gctcatattg aagtttatct ctatttacat
     4021 tcttactcta ttaaccacaa gttaaaccca tattgaagtt tatctctatt tacactctta
     4081 ctctattaac cacaagttaa gcccatattg aagtttatct ctatttacat tcttactcta
     4141 tcaatcatag gttaagctca tattgaagtt tatctttagt tgcaccttac tctattaatc
     4201 acaagttaaa cccatattga agtttatctt tagttacacc ttactctatt aaccacaagt
     4261 taaacccaca ttgaagttta tctctattta cactcttact ctattaatca caggttaaac
     4321 ctattataat cttaacttta ttcacaattt tattctatta gccacaggtt aaatctatta
     4381 taatcttaac tttattcaca tattacatca ttaatcgcat atcaagattt tataataagc
     4441 tttaactaaa cacacgattt taccttattc gtatagttta atctattaaa ttattatata
     4501 atcttaagca aacatacaac tctacactat taattatagc ccctcctttt aaatactcat
     4561 aatcttatac acaaccttac cttattaatc acacatttaa ctcatatata tcatcaattt
     4621 tattcacaaa atcatgctgt taatcacact tatactcctc tataatctta aacttataca
     4681 caaattagcc acaattttat ttcaactata ataacttcta tttcagaagt atatcacact
     4741 tgtattctcc aaaaatatct atttttttct aacaatatgc ctgacattaa taacactcat
     4801 ttcaaacatc ctcgctaatt ccatataatt tttcccatta aacaatttaa tcataagctc
     4861 atttctagcc tcttttaatg ccccttccag tgttttaata taaaaatatg ttcccccact
     4921 ttgttgacac aattcaaggt attccaataa actatactta tgtaactcct ttggaatact
     4981 tacttctatc ttgtgttctt caagtaattc tataattttc gttaattcca acatattttc
     5041 acctcatatt ttataatcta tttgctattt cctgactttt aataagcttg ttattactac
     5101 tttattgacc taataattta gttcttgaaa atgtaactta tccccaaagt aacaaaaatg
     5161 cttatgccta gtctgtccat ctctacactt cgcaactatt aaatcaacca tcttaattcc
     5221 cctgtattct gatgctctaa ctgcctcctc actttctcca atatctctca ctgcttcttc
     5281 ataatcactc ccctttaatt gatgtatata aaccacattg ttgctatcgt ggtagatggc
     5341 tttgctatcc ctcataggtc tatctccata aggtcttgaa tctttcattt catcatttaa
     5401 ctgacttaat tggattacag gtatattaaa atctaaagtc atatttttaa gttctctcga
     5461 aaaagtagct acctcccttt ctctcttatc catgcttttc tgagatgtaa ggagttgcac
     5521 ataatccact attaataaat ctggctttac ctgccttatc ctctttctaa ttgcactaat
     5581 tgtatctatc ttatcattaa tataaattaa gttattttcg cttaaatcac ctatagcatt
     5641 tacaataagt ttccaatcat tttcatctat ttctttagat ttcatattcc ttgtacttac
     5701 accagttact ctgcatatat ttctcataaa tacttgctca ctggtcattt ctctacttat
     5761 aaataaagtt tttttacctt gcttaaatga atttaacatt atttgaagtg ccaaagcagt
     5821 tttcccaacc cccgatttag ctgctattgt ggttagctct cctttaaaaa gacctcctat
     5881 agtagtatca agtaatttta taccaaattt aaatccaata tcttttttgt tttctaaaaa
     5941 atcaagcacc ttccctgcta tactatttac atcatcattt tcataagtat ccttgtccaa
     6001 aatctccttt atattacttt caaatttgta aatacaagta tcgatatttt ctccaaggtt
     6061 taggctgtgt aaaaggtttt ggcagttttg atttatgctt cttctagcta aattttcttt
     6121 taaaatttta atatgaccat caagaccaaa attctgaccc caagtaatta gattagtcac
     6181 atcactcgtt tttattgcta gagattttct atctatcttt gatttcacag tggccacatc
     6241 aatcactatg ttttcttttt taagttcttt cataatttta aatatctcaa gacatatatc
     6301 attcataaac atgttttcat ttaattcatc tagcttatag cttaatttat tgtctaaaag
     6361 aattgtgcct aaaatagact tctctatttc aacatctttt gatttaccca tataaattaa
     6421 tctctctttc cttataagtt tttatatttt gatttttaaa tacattatca attataaata
     6481 cattatttgt tatgactcac tatttgttat gactatatta ttcgtcatga tatactacaa
     6541 attattaata tactatttat tctgatacat ataatttact acataatagc aatatcttat
     6601 ttgatataac ttactaccaa ttattaatac attgttcaat ataattcatt actcgatagt
     6661 aatatcttat ttgatataac ttactgccaa ttattgatat atcgttcaat ataattcact
     6721 acctgatagt aatatcttac tt
//
LOCUS       DAMJWO010000129         6741 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.134, whole genome shotgun sequence.
ACCESSION   DAMJWO010000129 DAMJWO010000000
VERSION     DAMJWO010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6741
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.134"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            411..1685
                     /locus_tag="PC366_003444"
     CDS             411..1685
                     /locus_tag="PC366_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDF2578927.1"
                     /translation="MQFMDVSKYIEGANLKVKTKNGETVKRIYFNNSATPLVLKNVVD
                     NLNCEIPWLTYINAPGIISEKNTLKYENVRSTILKLIDGDEEKDSAIYVKNATEGINF
                     LAKFFKDENPDKFIITTAMEHMANYLPFKVNFPTKVVGITEKGELDLCQLENILKNYA
                     GNVSLVTVTGASNVTGITTPIYEIARIAHKYGAKILVDIVQVIQHKPFSMMPHECDEH
                     IDFVVFSAHKCYSPLNGGALVGPKKFFEKFNPVLYGSGSTKFVNDNKILYANVPQRFE
                     AGYPEYFGTLAMGKALNTLNKIGLNRISKYERELFLYAKEEMSKIPNIIIYGDKSNNV
                     IIPNISFNISNMYYKDVAKYLVDNFGIETGAGVVGADIYVQKLLGISPKEAYVRFMRE
                     NPVGLVRISLGMYNTFDEVDSFIHAIKTLAFK"
     gene            complement(1892..2209)
                     /gene="trxA"
                     /locus_tag="PC366_003445"
     CDS             complement(1892..2209)
                     /gene="trxA"
                     /locus_tag="PC366_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDF2578928.1"
                     /translation="MVKIINNNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYEALG
                     NEMVEKANFLKVDIDQSIELAQKFEVSTVPTMLIFKDGKPVDRLIGFMPKENLKNKIE
                     SYM"
     gene            2476..3228
                     /locus_tag="PC366_003446"
     CDS             2476..3228
                     /locus_tag="PC366_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HDF2578929.1"
                     /translation="MDNIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYIPINPNELLKNKKKEFDNSMDNLKNSLQILNKN
                     KSVEYVLNIKGDKNILKKALEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKSLKGLDNIHTHGGNKTTLENKMLYKGIILIVDNDEILTGNLSEGSEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQN"
     gene            3215..4096
                     /locus_tag="PC366_003447"
     CDS             3215..4096
                     /locus_tag="PC366_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HDF2578930.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTDASNISDEIKQNVAKEMN
                     LSETAFVSESNVADFKVQFFTPGLEVDLCGHATIGTFHALLEEGRLNTNKSIFYQETK
                     AGVLSVELKEINNENIFMMEQNTPEFENLDNYRKELAQMIGVHEDRLLEYPIIKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVHHNILDKTSFIGEQGNFINRPGKVYVNITRENNDITS
                     VKIGGSAYTVLSGEIMY"
     gene            complement(4322..5677)
                     /locus_tag="PC366_003448"
     CDS             complement(4322..5677)
                     /locus_tag="PC366_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDF2578931.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYASKYLIYIFLTTAI
                     VHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDSQEELDTAFSVQYSFVNIGSFI
                     GTIAVGILYLKTFAKNGVLGFSQCFFIAAVLCVIGAIWFIYGWRFLGNAGKRPFKEGV
                     VAEKVEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVNMNVG
                     GFDVPLAWFDSLNSLVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFSRGVGAPETAKASILWIIMFGILLSLGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGKGYGYIYAFTLKFDMIKVYTIIPVILFVAAILLFLSDKTLSRLVEDD
                     K"
BASE COUNT         2598 a          958 c          836 g         2349 t
ORIGIN      
        1 tataacatat aaaatctttt tttctaatta tatacaatat attttccatt atgttctaat
       61 caatttcttt actattttta caactttatt agtcatattc ataattattt ctaattagtg
      121 tttaacattt tatgtaaaat ttataaaaaa atgtatataa attaaaataa gtgactatac
      181 taaaaatatg atacggataa acaataagtt caacctatct cccccaaaat caagtgagct
      241 acagtttccc ccaactgtag ctcattttcg tgtaatttaa taaacatctc aacaagaatt
      301 aattaacaaa accccttata aaaacataac atatattaaa caagctcttg attaaaactt
      361 gagctttttt aataaaaaac agaatagttt attagataag gggttttttt atgcaattca
      421 tggatgtatc taaatacatt gaaggtgcaa accttaaagt taaaactaaa aatggtgaaa
      481 ctgttaaaag aatatatttt aacaactctg ccactccatt agttttaaaa aacgtagtgg
      541 ataacttaaa ctgtgagatt ccttggctta cttatattaa tgctccagga ataatctcag
      601 aaaaaaatac tttaaaatat gaaaatgtac gctctactat cctcaaactt attgatggag
      661 acgaagaaaa ggattctgct atttatgtca aaaatgctac agaaggaata aacttcttag
      721 caaaattttt taaagatgaa aatccagata aatttattat taccacagca atggagcata
      781 tggctaatta cctacctttt aaagttaatt ttcctacaaa agttgttgga attacagaaa
      841 aaggagaact tgatttatgt caattagaga atatacttaa aaattatgct ggtaatgtat
      901 ctctcgttac agttacagga gctagtaatg tcacaggtat aaccactcct atatatgaaa
      961 tagcaagaat agctcataag tatggtgcaa agatattggt ggatattgtg caagtaattc
     1021 agcataaacc tttttcaatg atgccacatg aatgtgatga gcatatagat tttgttgttt
     1081 ttagtgctca taaatgttat tctccactaa atggaggagc tctggtagga cctaaaaaat
     1141 tctttgaaaa atttaatcct gtactatatg gctcaggttc taccaaattt gtaaatgata
     1201 acaaaatact atatgcaaac gtaccccaac gttttgaagc aggataccca gagtattttg
     1261 gaactcttgc aatgggaaaa gcactgaaca ctttaaataa aattggtcta aacagaattt
     1321 caaaatacga aagagaatta tttttatatg ctaaagaaga aatgagtaaa atacctaata
     1381 taataatata tggagataaa tcaaataatg taattatccc aaatatatct tttaatataa
     1441 gtaatatgta ttacaaagat gtagcaaaat atttagttga taactttgga atagaaactg
     1501 gagctggagt agtaggtgca gatatttatg tacaaaaatt attaggtata agtccaaaag
     1561 aagcatacgt cagatttatg agggaaaatc ctgtaggtct tgttaggata agcttaggaa
     1621 tgtacaatac ttttgatgag gtggatagct ttatacatgc tattaaaact ttggctttta
     1681 aataagcttt ttctattctt ttttatcaat aaatagagag tagttttgtt ttcacaaaaa
     1741 aacaaattat atcaacagtc aatttcatta gcaattagac actcatttgt aactatacaa
     1801 actattttac actatacaaa taaaaaactc attacaatga gtttttttgt ttatatatga
     1861 tatttatttt aattacttca atttacttta attacatata tgattcaatt ttgtttttta
     1921 aattctcctt aggcataaaa cctattaatc tatctacagg ttttccatcc ttaaatatta
     1981 gcatagttgg tactgtagat acttcaaatt tctgagctaa ttctatactt tggtctatat
     2041 ccaccttcaa gaagtttgct ttttcaacca tctcatttcc taaagcttca tatattggtg
     2101 atagcatctt acaaggtcca caccaagtcg caaagaaatc tacaactact aaaccatctt
     2161 tattttctac ttcatttata aattcattat tatttattat ttttaccata atatacatct
     2221 cctttattat cttcttgata ctaatatact acgccctata taacagttca attaggcact
     2281 tttttgtaac cgcctatttt taatagattt aatattatga taaatagatt tataagatta
     2341 aatatttata agactaaata tttctgatat attttatttt tttcttaata tagttgacat
     2401 tttctccctt aaattataaa atcaaattaa taactacata ggtagttact aatcttttat
     2461 caaaggagtt tctatatgga taatataatt aatgaattac aaaatatagg atttactaaa
     2521 tacgaatctc aaatatacat atcattatta aaggaaagcc ctttaacagg atatgaaata
     2581 agtaaattat caggtgtacc acaatcaaaa gtctatgaaa atataacaaa gctattaaac
     2641 aataatataa ttatcaatgt tggaactgac cctattaagt acatacccat aaaccctaat
     2701 gaattattaa aaaataagaa aaaagaattt gataattcta tggataatct aaagaatagc
     2761 ttacagatat taaataaaaa taaaagtgta gaatacgttt taaacataaa aggagataaa
     2821 aatatattaa aaaaagcatt agaaatgata aaaaatgcaa aacaagaaat tataatttct
     2881 tgcccttatg aagaaattct tgaattaaaa aaagaactcc taattgctta caaaaaaaat
     2941 attaatattg aaatactact tttagaaaac aaaagtctga aaggtcttga taatattcat
     3001 actcatggag gtaataaaac tacacttgaa aataaaatgc tttacaaagg aattattttg
     3061 attgtagata atgatgaaat attgacagga aacttatcag aaggcagtga ggccatttca
     3121 atttggacaa aaaactctaa cattttatat attggagttc aatacataaa acatgaaatt
     3181 tatatttcag aacaaataaa aggaggttat aaaaatgaac aaaattaaga ttaaacaagt
     3241 tgatgctttt acaactatac cttttggtgg aaatcctgct ggtgtcgtta ctgatgcctc
     3301 taacatttct gatgaaatta agcagaatgt ggctaaagaa atgaatttat cagaaactgc
     3361 atttgtttca gagtcaaatg ttgcagattt taaggtacaa tttttcacac caggtttaga
     3421 agttgattta tgtggtcatg caacaatagg tactttccat gcacttttgg aagaaggaag
     3481 gcttaatact aataagagta tattttatca agaaacaaaa gctggtgtat tatctgtaga
     3541 gcttaaggaa ataaataatg aaaatatatt tatgatggaa cagaatacac ctgaatttga
     3601 aaatttagat aattacagaa aagaacttgc acaaatgata ggtgtgcatg aagatagact
     3661 tcttgaatat cctattataa aggtaaatac tggactttgg tggcttgtat ttggtctaaa
     3721 atctttagat gatttaaaaa atatctctcc agatttaaat aaaatcaaaa aatttagtgg
     3781 tgataataat ataattggta taactccatt ttgtatagaa actatagata aaaagtgtga
     3841 ctaccattta agatctatag caccatatgt tggagttaca gaagaccctg tatgtggaac
     3901 tgggaacgct tgcgtatcat cttatatagt acatcacaat attttagata aaactagttt
     3961 tattggtgag caaggtaact ttataaacag acctggaaag gtatatgtaa atataactag
     4021 agaaaacaat gacataactt ctgtaaaaat tggaggaagt gcttatactg ttttaagtgg
     4081 tgaaattatg tattaatccc atacctaata aaaacaaata aaaatactag ctaactaaag
     4141 ctagtatttt tatttgttat ttttatttaa taatcacact ctaacaaata ttataattat
     4201 atatatcata atattgtatt tagaagtaaa attttatttt tattattaat tagttataaa
     4261 tcaatctaat acaacataat tacagtagat taatctataa aacataataa ttacttactg
     4321 attatttatc atcctcaaca agtctactta atgtcttatc agataagaat aataatatcg
     4381 ctgcaacaaa tagtattact ggaattatag tatatacttt aatcatatca aatttaagag
     4441 taaatgcata tatatatcca tatcctttac cagctataaa agtagcaaat gtccatactc
     4501 ccataagaac acctagaagc ttcttaggtg catacttact tacaaaagag ttaccaagtg
     4561 gtgagaataa catttcacca agacttaaaa gaataccaaa catgattatc catagtatac
     4621 tagctttagc agtttcagga gctccaactc ctcttgaaaa ttctgcacca acaagcatta
     4681 agaatgcaag acctaagaat attaatccaa gacctgtctt tttaaataaa ctcatatctc
     4741 cttgtggtct actagcaagt ttaaaccata atgctccaag aactggtcct aatactatac
     4801 atacaagtga atttaatgag tcaaaccaag caagaggaac atcaaatcct ccaacattca
     4861 tgtttacaaa tgctgcacca taatcataaa ctgcaagata agttagatac cagaataccc
     4921 agaaaattac agagaagaat gatataagta taatagccca aattctcttc ttatccatgc
     4981 ttgtaagagg agacttatct ttttcttcaa ctttttcagc aactacacct tctttaaaag
     5041 gtctctttcc tgcatttcca aggaatctcc atccatatat gaaccatatt gcacctatta
     5101 cacaaagtac agctgctata aagaaacatt gagaaaatcc aagtacacca ttttttgcaa
     5161 atgttttaag gtaaagaata ccaactgcta tagtaccaat aaaagaacct atattaacaa
     5221 aagaatattg tactgaaaat gctgtatcaa gttcttcttg actatcaaaa agctgtccat
     5281 ttaccgcaga tacgttacct ttaaagaatg cagtaccaat cgaaactaag attatcattg
     5341 catttaccat agaaactgta gttgcaatag aaccaagata gtaacctacc cccatgataa
     5401 gcatacctat aggtatagta tatctagctc ctatccatct atctgatata tatcccccaa
     5461 ttataggtgc aaggtatgtg aatgcaacaa ggttggcttg cattatagca gcttgtcctt
     5521 tatctattcc aagaccacca tgaactatag ctgttgtaag gaatatatat attaagtact
     5581 ttgaagcata atatgctgct ctttcaaatg agaaagttgt tgagcagata taaaatccca
     5641 taggaaattt acccttcttt tttactgttg agctcataat tttaaatcct ttcttaattg
     5701 tatttttatt ttttacgttt tgtccaaatt ctttctttta tgaaagatat aatattatta
     5761 ttttgtaaaa caatttgtaa ttattattaa gataattgcg catttatttg tagagtacat
     5821 attctcatgg aataaaatta atacacttct taatcataaa tttaaattat ataaattcac
     5881 tattttcaga tatagttata aattaatata ttctcatcta ataccatgaa aaaaccttcg
     5941 ccatatgcaa ttcttatttt ttacgtgata gtattttaca aactaaaatc ccccttttgt
     6001 agcaacttct gtaattacat tttagtgctt ttttaaagga gtctcgaata aagcaacata
     6061 tattttgttc aaataatgtt tttatttact ttttaaattt atatattact tcactcaacc
     6121 aattctcaac ttaaataaat aaactactat ctattcacag attagaccta tttcttacac
     6181 attagtttat aataaacact gtgaatctaa acataaaaac tgttatttta aagtaattac
     6241 ccatatattc gctttgatac tatttattga ggttatactc tttatttata atatattatt
     6301 tataaaatac ctcaaaatat attattaata aaatacctca aactgaaaac tttttcacga
     6361 atatttattt ttcacctccc cttttttatt ttaccatgta aatcgtacca taaatatgca
     6421 cttatatgca agaaaaaaat ctattaatcg acagtaaata attagaaaaa tttaaattat
     6481 atttgttaag tgtattatat aaaatatttc ctatgaaaat ataaattaaa ttaatgttca
     6541 gaatagtttt tagatatgaa atcttgattt ttttattact ttacttattt gctcaaatat
     6601 atttttgtat gcagtatata ataatcaaat tatacacttc ttataactgc gttgatttga
     6661 aaataatatt aatagttaat agaagaaaaa atttaaatta atttttaaaa aatctattaa
     6721 gttaattgaa tactttttta t
//
LOCUS       DAMJWO010000130         6626 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.135, whole genome shotgun sequence.
ACCESSION   DAMJWO010000130 DAMJWO010000000
VERSION     DAMJWO010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6626
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.135"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            9..911
                     /locus_tag="PC366_003449"
     CDS             9..911
                     /locus_tag="PC366_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HDF2578932.1"
                     /translation="MLPQDYYGLIVILGVILGVMGAFYNWFTLYVQSLYKKIPKIATF
                     GKLLIPFIMAGILGIVMPDVLGSGHNLVEELTSHEYIFGMVVLIFVIRFIFSAVSFGS
                     GAPGGIFFPLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTG
                     IILIFEMTGSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKERGE
                     KILDQFSVMFGSPVANKAIQDVQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVTMT
                     DERDSGAVYDKMENLCKEHTSHIF"
     gene            1520..2533
                     /locus_tag="PC366_003450"
     CDS             1520..2533
                     /locus_tag="PC366_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HDF2578933.1"
                     /translation="MVSSFLNDIFRTILVSCIFIVILLVFRITLFKTFSKKFNYYIWL
                     IVIIKLSLPFMNYTFIFNESKYNGNINKISLGNFNSISIVYSTVLVSVWIAITIFYLV
                     YTLLKYIKLKNMINDLSYDVEDDKIKNLYENLLKELKINKKIRLKYSYEVESPVFFNS
                     CVILPPCDYTLKELNWIFRHELMHFKSKDLYIKYLVIFLKCVYWFNPFVYIMEKFIDL
                     DCEFYCDERVLKNCTIEEKQDYALTIISAMRKGSNSSNKFVAGLHKESDIKKRVFSMF
                     NEKYRNGILIAVILCLLSSITYFEIDLITTKSIFYPLSKQTPIENRTNSKPTYQINVY
                     IDN"
     gene            2889..3458
                     /locus_tag="PC366_003451"
     CDS             2889..3458
                     /locus_tag="PC366_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HDF2578934.1"
                     /translation="MKKKLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTGILP
                     MQKIVRISHIGSTSVSTIYAKSIVDILIEIIPDYNMKDIKDLIESNGYICMSESSSRL
                     SLNKGYTVDGFEERVFHLHIRYVGDNDELFFRDYLIDHPDVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKVLYSNRYN"
     gene            complement(3795..5132)
                     /locus_tag="PC366_003452"
     CDS             complement(3795..5132)
                     /locus_tag="PC366_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2578935.1"
                     /translation="MDTYSLISTSINFILILINIFIAFFLYKLTSYFIDFRNHWIFKI
                     ILILGYSIISQMIIWLSDPVNILFTLFGYFILLIICSKSKLIPIISVVMILYPIIIGL
                     NFLFINNPIYEELIHSKEYILILSIVQIISALIKLLFWFLIHIFLKNRLVNIKQYLSN
                     KIWIFIDMVCISSFLSILIAIILPPTNLIPMGSNKNIILGNLPYGTYLIILSAILANI
                     GVILLLQPLIENVKMKIEKQANHLKEKYYNLLENQQIQIRKMRHDMNNHFQMIESYLE
                     IEDIAGAKKYFNQLKIGIGTLSGKQFCKNQALNSILNLRHTSLEENGVDVHFNIDIDN
                     HLGIEPIDLCTIFSNSLDNAIEASLKIPDLSNRKVVLKARCEKEYFSYLLTNNKVNPI
                     NRKQELFISDKKDSNSHGYGIENIREIVNKYNGKLDISYTENEFSLFLYIRLF"
     gene            complement(5572..6282)
                     /locus_tag="PC366_003453"
     CDS             complement(5572..6282)
                     /locus_tag="PC366_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2578936.1"
                     /translation="MTSICICDDEKQQRNMLNKIITREMDLWGYPYQIKEYSNGESLV
                     YNLEHENYYIDIIFLDIELEKSNGVDIAKTIRKHSKDTIIIFVTGFSDYVFHGYDVGA
                     LNYILKPYKTEKICKVLKEALKKLEQWKENFITVHIGTNLCKINTKDILYFKSELRKL
                     TVVTFDKTLEYYGKLNDMETVLPSNFIRTHQRYIVNLNHVDSITQTYAKVQNEKIPIS
                     RKKYQEVVGKFTRYMLEP"
BASE COUNT         2457 a          695 c         1001 g         2473 t
ORIGIN      
        1 ttggaaatgt gttgccacaa gattattatg gattaatagt gattttaggt gttattcttg
       61 gagttatggg ggcattttac aactggttta ctctatatgt gcagtcttta tacaagaaga
      121 ttcctaaaat tgctaccttt ggaaaactgt tgattccatt tataatggct ggtattcttg
      181 ggattgttat gcctgatgtt ctggggagtg gacacaattt agttgaagaa cttacaagtc
      241 atgaatatat ttttggaatg gttgttttga tttttgttat acgttttata ttttcggctg
      301 ttagttttgg gtcaggtgca ccagggggaa tattttttcc attgcttgtt ttaggagcat
      361 ttataggtgg aatatttggt atggtaggtg ttaaagtttt tggaatgaat cccgattatg
      421 taaataactt tgtgcttttg gctatggcag gatattttac agctattgtg cgtgcccctt
      481 tgactggtat catattaatt tttgaaatga caggttctgt tagtcaaatg ctttcactat
      541 cagtaatttc aattgtggca tatattgtgg ctacacttat gaagtctaaa cctatttatg
      601 aaagtcttct tgagaggtta cttgaaaaaa atggagaacc tgtacataaa gagaggggcg
      661 aaaagatact agaccagttc tctgttatgt ttggctctcc tgttgcgaac aaggcaattc
      721 aggatgtaca gtggcctgaa aattgtcttt tggtagcaat tcaaagaggt ggagaagaaa
      781 ttattcctag aggtaagaca attcttagac caagtgatgt aattgtgact atgacagatg
      841 agagagatag tggtgctgtg tatgataaga tggaaaattt gtgtaaagaa catacgtcac
      901 atatttttta gggataatga tgaatgttta ataatgatag aatatttaat gaagatttga
      961 ttaaaaaatt ggtaatttga aagagagtta aggaattaat agaaaatgaa aatgtgatat
     1021 cttagatgta aaagagtttg aagaaaataa ttgtatatat ttgttaatga gattatatgg
     1081 actaatggta tatttatact gtgctaaaag ttgcactatt gtatgaggaa tgggaataaa
     1141 gggtttgaaa aaataggtag aagatttttc agatattctt attgggatat tttaattaat
     1201 atattttaat tgcgatattt tgggaagaat agaatttatt tataaatgaa aataattaaa
     1261 aggggttaag gttgtattag ccccttttgc ttatagagtt tggaaatggt atcttgatag
     1321 cagttgtttt atgcttatta tattttatta catattttaa aattaacctt atcactccta
     1381 aatcattatt ctatcaactt ttaaaacact ttcaagacaa tcacctattg aaaacaaagt
     1441 taattaaaaa cctacatatc agtttagtat tcgtgtagat gattatataa atataaaagt
     1501 ataagaaagg tgagtatctg tggttagttc atttttaaat gatatcttta gaacaatttt
     1561 agtaagttgt atttttatag ttattttatt agtctttaga ataactttat ttaagacttt
     1621 cagtaaaaaa tttaattact atatatggct tattgtgatt attaagctat cattaccatt
     1681 tatgaattat acttttatat ttaatgagtc aaaatataat ggtaatatta ataagataag
     1741 tttaggcaat tttaatagta tttctattgt atatagtact gttttagtct ctgtttggat
     1801 tgctattacg atattttatt tagtttatac tttattgaaa tatattaagc ttaaaaatat
     1861 gataaatgat ttgtcttatg atgttgagga tgataagata aaaaatcttt atgaaaattt
     1921 attaaaagag cttaagataa ataaaaaaat acggcttaaa tattcatatg aagttgaaag
     1981 tccagtattt tttaattcgt gtgtcatttt accaccatgt gattatacat taaaagagtt
     2041 aaactggata tttaggcatg agttgatgca ttttaagagt aaagaccttt acattaagta
     2101 tttggtgata tttttaaaat gtgtttattg gtttaatcct tttgtgtata taatggagaa
     2161 gtttatagat ttggattgtg aattttattg tgatgaaaga gttttgaaga attgtacgat
     2221 agaagagaag caggattatg cattgacaat aattagtgca atgagaaaag gttcaaatag
     2281 ttcaaataaa tttgtggctg gattacataa ggagtcagat attaaaaaaa gagtgtttag
     2341 tatgtttaat gaaaagtaca gaaatggtat tttgatagca gttattttat gtttattatc
     2401 ttctattaca tattttgaaa ttgatttaat tactactaaa tcaatatttt atccactttc
     2461 aaaacaaaca cctattgaaa atagaactaa ttcaaaacct acatatcaga ttaatgttta
     2521 tatagataat taaaaaatac aaagtttaac aagagattaa tataaataat tttaataagt
     2581 atctttcaca tatgttaaat ttactttaat tatattaaag ccaatgaatt attctttaga
     2641 agctccaatg ccagtaaata caggtaaaga aaaatctttt actacaattg taaattaaaa
     2701 aatattctaa tatttaaaga aatgcaaaag tgtaagaagg gtaaaaatct gttataatac
     2761 attaaaaact aaatttagaa aaatttacat aattagaaaa atgatttgat aaaaaataaa
     2821 gttaaatatt aactaagtaa atttgaaaaa gaaaaaatat aaagtacaaa tttaaaagga
     2881 ggtaactaat gaaaaagaag ttggaagata tgactttaga ggagttatgg aacttgtttc
     2941 ctatattttt gactactcac aaagaatgtt ggaaaaattg gtttaaagaa gaacaatata
     3001 gactaactgg aatattgcca atgcaaaaaa ttgttagaat aagtcatatt ggaagtactt
     3061 ctgtgagtac gatttatgcc aagtccattg ttgacatact gattgagata attcctgatt
     3121 ataatatgaa agatattaaa gatttgattg agtcgaatgg atatatttgt atgtctgaga
     3181 gcagtagtag gctttcactt aataaagggt atacagtaga tgggtttgaa gaacgcgttt
     3241 ttcatttgca tataaggtat gtaggtgata atgatgagtt gttttttaga gattacttaa
     3301 ttgaccaccc agatgttgca aaggagtatg aaaaacttaa gttggacctt tggaagaagt
     3361 atgagcataa tcgtgatgct tatacagata gtaaactaga ttttgttagg gagtttactg
     3421 aaaaggcaaa ggtgttgtat tctaatagat ataattagaa ataggtacaa ttagatattt
     3481 atcttatata tcgtattata ttttttaaga aagtaattaa tagaaaaagg ggttgtttca
     3541 aaatggagag ataaatccct ttttcattgt tgaaatgata aaaatatatt tgatttcatg
     3601 taaaaaagag tgcctcatca actaaaaagt ttattttgag acacacacat ttttattaag
     3661 gtaaataaaa atatcacatt tgattaaatt ttaagttaat gaatatatgt gtaaatattt
     3721 aattataagt tattataatt ttacatagta taaaacaatc taatttgtat tatataagat
     3781 aatctaattt tagactaaaa taatctaata taaagaaata gagaaaattc attctcagta
     3841 taagagatat ccaattttcc attgtactta ttaacaattt ctctaatatt ctcaatacca
     3901 tatccgtgag aattactatc ttttttatct gaaataaata gttcttgttt tctattgata
     3961 ggatttacct tgttgtttgt caataaatag ctaaaatact ccttctcaca acgtgccttt
     4021 aataccactt ttctatttga caaatcagga attttcaaag atgcttctat agcgttatct
     4081 aaagaatttg aaaaaatagt acataaatct ataggttcta tacccaagtg attgtctata
     4141 tctatattaa agtgcacatc aacaccattt tcttccaaac ttgtatgacg aagatttaaa
     4201 attgagttaa gagcttggtt tttgcaaaat tgtttgccac taagagtacc tatacctatt
     4261 tttaactgat taaaatactt tttagctcca gcaatatctt caatttctaa atacgattca
     4321 atcatttgaa agtgattatt catatcatgt cgcattttgc gtatttgaat ttgttgattt
     4381 tctagtaagt tatagtattt ttcttttagg tgatttgctt gtttttctat cttcatcttt
     4441 acattttcaa tcaatggctg taaaagaagt atcacaccga tatttgccag aattgctgac
     4501 aagatgatta gataagtgcc ataaggtaag ttgcctaaga taatattctt attactaccc
     4561 atagggatta aattagtagg tggcagaata atagcaatta atattgataa aaatgaagat
     4621 atacatacca tatcaataaa aatccatatt ttatttgata agtattgttt tatattgacc
     4681 aatctattct ttaggaaaat atgtattaaa aaccaaaata ataatttaat tagagcagaa
     4741 attatctgga ctattgaaag tattaaaata tattcttttg agtgtataag ttcctcatat
     4801 atagggttgt ttataaaaag aaaattaagc ccaattataa taggataaag tatcatgaca
     4861 actgatatta taggaattaa tttgcttttg ctacatatta taagtagtat aaaatatccg
     4921 aatagtgtaa acaaaatatt tacggggtcg gaaagccata ttatcatttg actaataata
     4981 gagtagccca aaatcaatat gattttgaaa atccaatgat tcctaaagtc tataaaatag
     5041 gaagtcaact tataaagaaa aaaggctatg aaaatattga ttaatattag aataaaattt
     5101 atgcttgtag agattaaaga ataagtgtcc atttaatata cctttctatt aattaagatt
     5161 ctggaaacta agttttaaaa aattaaatct taaaaattaa aattctggaa attagatttc
     5221 aaagaattga ttttgaaaaa taaaattcta gaaattaagc ttcaaaaaat tgagttttga
     5281 aagattgaaa ttttaaaaat taagtttcaa aaaattaaat ttgaaacaaa actctaaaaa
     5341 ctaagcttca aaaaattaaa ttttgaaaga ttgaaattct agaaactaag ctttaaaaaa
     5401 ttaagtttca aaaaaactct aaaaactaag cttcaaaaaa ttaaattttg aaagattgaa
     5461 attctagaaa ttaagcttca aaaaattaaa tttgaaaaaa caaaactcta aaaactgagc
     5521 tttaaaaaat taagtttcaa aaataaaatt ctagagattg aacttcaaaa attaaggttc
     5581 taacatatac cttgtaaatt ttcctacaac ctcttgatat tttttacggc ttataggaat
     5641 tttttcattc tgaactttgg cataagtttg agttatacta tctacatggt ttagattgac
     5701 aatatacctt tgatgcgtac gtataaaatt agagggaaga acagtttcca tatcatttaa
     5761 ttttccgtag tattctaatg ttttatcaaa ggtaactaca gttaattttc ttagctcgct
     5821 tttaaagtag aggatatctt ttgtattaat tttacaaaga ttagttccaa tatgaactgt
     5881 aataaagttt tctttccatt gttctaattt ttttagtgct tcttttaata ctttacatat
     5941 tttttcagtt ttataaggtt ttaagatgta gttcaaagct cctacatcat acccatgaaa
     6001 tacatagtca gaaaaacctg tgacaaagat gattatagta tcttttgaat gttttcgtat
     6061 agtttttgct atgtcaacgc cattactttt ttcaagttca atatctaaaa aaataatatc
     6121 tatgtaataa ttttcgtgtt ctagattgta tactagactt tctccatttg aatattcttt
     6181 tatttggtag gggtagcccc acaaatccat ttctcttgta atgattttat tcagcatgtt
     6241 tctttgttgt ttttcatcat cacaaataca aatcgaagtc aattttttat ctcctttcaa
     6301 gttttatatt tatatagtta agtatataat atattttgct acctagatat ataaaatgaa
     6361 ataacaatta tatccagata gcaaaataaa attttttata ttagtatact tacacttaaa
     6421 actattctat taaacttatt ctgaagtgct aatgattttc ttattaaaaa atctaataac
     6481 ctttcttatt ataaaatacc aatgctttta ttattataaa aatgtaatga cttttcatat
     6541 tataaaaagc aaatgattat cttactataa aaatacaatg acttttaata ctataaaaag
     6601 caaataatta tcttactata aaaatg
//
LOCUS       DAMJWO010000131         6598 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.136, whole genome shotgun sequence.
ACCESSION   DAMJWO010000131 DAMJWO010000000
VERSION     DAMJWO010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6598
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.136"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..656)
                     /locus_tag="PC366_003454"
     CDS             complement(<1..656)
                     /locus_tag="PC366_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HDF2578937.1"
                     /translation="MKKDTSHIIKRAEHFQVILIGEGLMVGAVAGLIVLLYRILLGQA
                     GTWLSQILKFVEGSTIKIIAWFAVLAVLAWIVSKLVDWEPMISGSGIPQLEGEMTGKI
                     KQVWWRVLPTKFIGGFLSLMGGLALGREGPSIQLGAMAGKGISRALDRGKTEEKFLLT
                     CGASAGLSAAFHAPLAGVMFSLEEVHKNFSVSVLISVMTASLTADYISANFLGMESVF
                     "
     gene            complement(843..1352)
                     /locus_tag="PC366_003455"
     CDS             complement(843..1352)
                     /locus_tag="PC366_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HDF2578938.1"
                     /translation="MIGLKCGMVKLLEHQMIWDKSAKDVIILLKSIWDKTAIDIQHIG
                     STSIPSISAKPIIDIVVGVASLEEAKLYLERLEQCGIVFRGQDVPKQLLFAMGDFEKN
                     TRTHHIHVVEWNSVAWNNYINFRDYLNTFTDKAKLYDSHKQKLALQFEDNRKIYTQRK
                     QELINILLE"
     gene            complement(1427..1840)
                     /locus_tag="PC366_003456"
     CDS             complement(1427..1840)
                     /locus_tag="PC366_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HDF2578939.1"
                     /translation="MKMPKESIDTIMFAPCGMNCMVCYKHCYHKKPCAGCLNSDTGKP
                     EHCRKCKIKDCVCQKGLFYCFECFNFPCKLIKNLEKSYNKRYQASLMENSKFVQQYGL
                     EKFMQKQKERYTCSKCGGIISIHDRECSECQEKVK"
     gene            2277..2936
                     /locus_tag="PC366_003457"
     CDS             2277..2936
                     /locus_tag="PC366_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HDF2578940.1"
                     /translation="MDEKILELLQEIQGNISNMQGSISGIEGTVNGMQGNINYMQGNI
                     NYMQGTISDMQGTISDMQGSINGIEGTISDMQGSINGIEGTISDMQSNINDIEGTISD
                     MQGSISSMDGTINSMQDSITDMQGEIKEVNSRLDNMEPDIKDLKTGQVETSSRLDTIQ
                     SDVTEIKSDVKINRNTLDTVIKHTSSLVEDTSDIKNDLNNIEIVTSKNWNDIAKLKSV
                     K"
     gene            complement(3181..3336)
                     /locus_tag="PC366_003458"
     CDS             complement(3181..3336)
                     /locus_tag="PC366_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578941.1"
                     /translation="MVKFNQTLKVSKEKIITLKQEDINGKMKTRFYPFISDKGICFNQ
                     RWTFILG"
     gene            complement(3543..3722)
                     /locus_tag="PC366_003459"
     CDS             complement(3543..3722)
                     /locus_tag="PC366_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2578942.1"
                     /translation="MLQTGKQGADKKYLDNMFFVKGYVEELLFLDNSYDIVFSCIVFH
                     HCTNVQNIFCIFWKW"
     gene            complement(3947..4480)
                     /locus_tag="PC366_003460"
     CDS             complement(3947..4480)
                     /locus_tag="PC366_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDF2578943.1"
                     /translation="MQYISYYHSPIGNILLASDNVGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGEEPNFTPSLHMVGTPFQTTVWKILQQIPYGKTITYGEIA
                     HKVAQQKGISKMSAQAIGGAVGHNGISIIVPCHRVVGTNGSLTGYAGGIDRKIKLLSL
                     EKVSVQHYFIPKKGSAL"
     gene            complement(5298..5870)
                     /locus_tag="PC366_003461"
     CDS             complement(5298..5870)
                     /locus_tag="PC366_003461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDF2578944.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGSCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
     gene            complement(5932..6195)
                     /locus_tag="PC366_003462"
     CDS             complement(5932..6195)
                     /locus_tag="PC366_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HDF2578945.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDLYNRYCD
                     KFTQAVCDYESKYGALTNFGYESSEYPWSWISEPWPWDKSFYK"
     gene            complement(6195..6416)
                     /locus_tag="PC366_003463"
     CDS             complement(6195..6416)
                     /locus_tag="PC366_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HDF2578946.1"
                     /translation="MGYLKEDKQDYCCEFARPYINRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYSNPKNRVRAKKGGNMY"
BASE COUNT         2311 a         1135 c          812 g         2340 t
ORIGIN      
        1 tggaatacag actccattcc taggaaattg gctgaaatat agtctgctgt caaagatgct
       61 gtcatcacag aaattaaaac agatactgaa aagtttttat ggacttcttc aagtgaaaac
      121 ataacacctg ccagtggtgc atgaaaggct gctgataatc cagcacttgc cccacaggtt
      181 aacaggaatt tttcctctgt cttccctcgg tcaagagctc tagaaatacc tttacctgcc
      241 atagcaccaa gctgaatgga aggaccttcc cttcccaaag caagaccacc cataagtgat
      301 aagaatcctc caataaattt tgtgggcaac actcgccacc atacttgttt tattttccct
      361 gtcatttccc cctcaagctg agggatacca cttccagaaa tcattggctc ccagtccacc
      421 aactttgata caatccacgc aagtactgca agtactgcaa accaagctat tatttttatt
      481 gtagaacctt ctacaaattt taaaatttgg ctaagccaag taccagcctg ccctaaaagt
      541 atcctgtata aaagcacaat caaaccagcc acagccccaa ccataagtcc ttcaccaatc
      601 aaaattacct gaaagtgctc tgcccgtttg ataatatgag atgtatcctt tttcatactg
      661 ttcctccttc atccaataat tctacacaat ctgaacctcc aatgactaaa gtcatgagtg
      721 tgtacagata ttttttaatc aacaaaaata gatttttatt tactaaatat aagaaaataa
      781 ttgttcaatt tctcaataaa tgtaaattta ttcttttagg tatttattct ccacagtcgt
      841 gcttattcca gcaaaatatt tattagttct tgctttctct gtgtatagat tttacgattg
      901 tcctcaaact gtaatgctaa tttttgttta tgactatcat agagttttgc tttgtctgta
      961 aaagtattta gataatctcg aaaattgata taattattcc atgcgacact attccattca
     1021 acaacatgaa tatggtgagt acgagtattt ttctcaaaat ctcccatagc aaaaagtaat
     1081 tgttttggta catcctgacc tcgaaaaacg attccacatt gctctaacct ttcgaggtat
     1141 aatttagctt cctctaaaga agcaacacct acaacaatat caataatagg ctttgcgcta
     1201 atactgggaa tagaagtgct tccaatgtgt tgaatatcaa tggcagtctt atcccatata
     1261 cttttcaata atataatgac atcttttgca cttttatccc atatcatctg atgttccaat
     1321 aatttaacca taccacattt taaacctatc actatatacc acctcaatat aatccacctt
     1381 tatatatata ttacaatttt ttctatcttg ataaacagtg atctagctat ttcacttttt
     1441 cttgacactc gctacattcc ctatcatgaa tagatataat tcctccacat ttagaacaag
     1501 tatatctctc cttctgcttt tgcataaact tctctaaacc gtactgctga acaaatttac
     1561 tattttccat aaggcttgct tgatatctct tgttataact tttttcaaga ttttttatga
     1621 gtttacaagg aaaattgaaa cattcaaaac aataaaacaa ccctttttga cagacacaat
     1681 cctttatttt acacttacgg cagtgttctg gctttcctgt atcgctgttc aaacaaccag
     1741 cacatggctt tttgtgataa caatgcttat agcaaaccat acaattcatt ccacaaggag
     1801 caaacataat cgtatcaata ctctcttttg gcattttcat aacattttac tcctttcaaa
     1861 aatccaattt gtcgaattgt tatatattca tattgtaaca taaaaaatag ctaaaaaatt
     1921 catgcacttt cattgccaat aaattttcaa ggaaatatga aagtttaaaa ctaagaataa
     1981 aaagaaataa aaaggaagct actaatcaaa atattcaaac acaagtaatc aattatgata
     2041 ttaccagcag ttttaaatac aaatataacc acatatgcct caaaaacact tattatagta
     2101 tcttagacac ttagacaata cacaagattc attaataaaa aagttctcaa tatagatata
     2161 tttaaccatg ttttgaatag cagataatta tatgattaaa aattaaatat gacatagcgt
     2221 ttgtggaata taacacctaa attatgttat aataataaaa caggagtgtg atagtgatgg
     2281 atgaaaaaat attagaatta ttacaggaaa tacaaggtaa tattagtaat atgcaaggta
     2341 gtatcagtgg tatcgaaggt actgttaatg gcatgcaggg taatattaac tatatgcagg
     2401 gtaatattaa ctatatgcaa ggtactatta gcgatatgca aggtactatt agcgatatgc
     2461 aaggcagtat caatggtatc gaaggcacta ttagcgatat gcaaggcagt atcaatggta
     2521 tcgaaggcac tattagcgat atgcaaagca atatcaatga tatcgaaggt actattagcg
     2581 atatgcaagg cagtatcagt agtatggatg gcactattaa tagtatgcaa gacagtatta
     2641 ctgatatgca aggtgaaatt aaagaagtca atagtagatt agacaatatg gaacctgata
     2701 ttaaagactt aaaaactgga caagttgaaa ctagtagtag acttgataca attcagagtg
     2761 atgttacaga aattaagtca gatgtaaaaa ttaacagaaa tacattagat acagtgatta
     2821 aacatacctc ttcattagta gaagatacat cagatattaa aaatgattta aacaatatag
     2881 agatagtcac atctaagaat tggaatgata ttgctaaatt aaaatcagtt aaataatata
     2941 ccatagtaaa aaatacctga aaatttcaca tacttcttta aagttatacc aaattttata
     3001 cagaaatact gattatccga caacacactt tacttataaa taatttatta aaaaatactc
     3061 attttatcct aaaattaaca cgactaaatg agtcttgata taataataaa aaataaggga
     3121 gattgaacac taaaaagttg tgtatctccc ttatattcta taatatagtt atataatttt
     3181 tcagcctaaa ataaaagtcc atctttgatt aaaacatatc cccttatcac ttataaaagg
     3241 ataaaatctt gttttcattt ttccatttat atcttcttgc ttaagagtaa taattttttc
     3301 ttttgatact ttaagtgttt ggttaaattt aaccaatcga ctaagttttg ttcaacatct
     3361 atttttcata ttttccaata cttaatctat tttttataaa taattctttt atttctaact
     3421 cacttacatt ttttacataa aacgaagcat ataaatttca accttatctt gtatggttct
     3481 taatacttaa tgagtagctt aagtatcaat cattataaat tttcccctta tatttaacac
     3541 tcttaccatt tccaaaatat acaaaatata ttttgaacat ttgtacaatg atgaaataca
     3601 atacatgaaa atacaatatc ataactgtta tctaaaaata gaagttcttc aacataacct
     3661 ttcacaaaga acatattatc taagtatttt ttgtctgctc cttgttttcc tgtttgtagc
     3721 atataaatta ctgcatctaa acatataact actcacacga aaaaagaaaa taaacttcca
     3781 aaatacaagc tctaaaacta cctctaaagt tatataatgt ttactaggaa taaggttgta
     3841 taacatatag tttaaagaat agttttttaa aattgcaagt tattgctttc aaaattagat
     3901 gtttatatat caaataaatg attaagaatt tctaaattta atggctttat aatgcactcc
     3961 ctttctttgg gataaaataa tgttgcacag atactttttc taaagataac aattttattt
     4021 ttctatcaat tccaccagca taccctgtca aactcccatt tgttcctaca acacgatgac
     4081 atggaacaat aatagagatt ccattatgcc ctactgcacc accgattgct tgtgctgaca
     4141 ttttagatat tcctttttgt tgagcaactt tatgtgcaat ttctccataa gtgattgttt
     4201 taccatatgg tatttgttgt aaaattttcc acactgtagt ctggaaagga gtacctacca
     4261 tatggagtga tggtgtaaaa ttgggctctt ctcccgaaaa ataaatatct agccatttct
     4321 ttgtctgctc gaaaattggc aattcttttt cttgatgttc ttggtcaaga ttataagcat
     4381 aatacttttg attctcaaac caaagaccag ttaacccaac attatctgat gctaaaagaa
     4441 tatttccaat tggactatgg taatagctaa tatattgcat acaattcctc cttatattct
     4501 gaaaacttca ctcaaatcat tagacacttc ttttctatct gccattatgt aaaaacatac
     4561 taatataatt tccttctgac tacactttcg ttataatatc tatcctcata tcatattagt
     4621 tttatattta cctgaatctg ttcatccttt ttttcctttc cctttgatgg atataaaatt
     4681 catacattta agcttcctac tgtattaact tttatagaag tgtatattat aattttatca
     4741 ctaaatagac aaaaaaatat cgatataaca tcaagaaata ttttactgag tttcgcttat
     4801 taaaagcaac tgaatttcta aagggtacag atgagctaat aagtgatatt gatataaaag
     4861 ttgtttttca ttaagtaatc tattttagta aatgttttaa agaaaaaacg ggatattctc
     4921 caaaagtgta cagaaatata aaaaaagaga tatgattttt tatttctttt gattatccaa
     4981 agagtaaata aaaaatattg taaaaaactt actaacaacg gcaatgcttt gaactatggt
     5041 aatactttga acttttgatt ggactttttt tgctaaaata atatatttaa atagcaaagt
     5101 aatctgttta atcaataaaa aataagagat aaaagaaatc aactaaaacc tttacctctt
     5161 attttgatag tttatcagag ctaatattta cactcttttt atttttgata cttcattaaa
     5221 aatgatgctt attctctttt catttttaat acttcattaa aattgatgct tactctctat
     5281 tcacttttaa tacttaatta gaactgatgc ttacactctg taaactcata aacatccatt
     5341 aatgcttcac caaatctttg atagtgaact acttccctct cacccaaaaa tctcaatata
     5401 tctttcaaat cagggtcatc agttaaattt attaattgat agtacgtagc caatgctttt
     5461 tgttcagcag ccatatcctc atgtaaatca gttaccgaat cgccaaagac attaatataa
     5521 cttgtagtaa agtttactcc attagaatct actggttgaa gaccatgtcc aaaattagca
     5581 taattactac caagtccagc agccttaagc tcttccggag tacaactgcc tattaattga
     5641 tataacactg aagaaattat ctcaacatgg gccatttcct ctgtacctat atcagttaaa
     5701 agtgcgcgag attttccagt tggcatagta tatctttgtt gaagatatct agttgcagct
     5761 gccaactcac cattaggtcc tcccaactga gtcatgatat attttgccat tctagggtct
     5821 gcttgtctta tgttaactgg atgttccagt gttttttgat aaatccacat attatcttac
     5881 tcctccttaa tatatattta ataataattc taattttaaa acttaataat tttatttata
     5941 aaatgatttg tcccatggcc aaggttcaga tatccatgac caaggatatt cacttgattc
     6001 atatccaaaa ttagttaatg ctccatattt agattcataa tcacacacag cttgtgtaaa
     6061 tttatcgcag tatctattgt ataaatcaag agctttctta tcccttggat tgttatctaa
     6121 atataaattt aattctatac aggcaaattg atattctgaa attctctcta aaagttctct
     6181 tctatttaat gacattagta catgttaccc ccttttttag ctctaactct atttttagga
     6241 tttgaatata gccaatcatt atagttattt gactctatta aatctaattc aggaaataaa
     6301 gtacctcttt ttaatgctgt ttttggattg tatgtgtcat cataaatttg acgattgatg
     6361 tatggtctag caaattcaca acaatagtct tgtttatcct cttttaaata tcccattaat
     6421 tatcctcctt aatttttaga attttaaaat agcattattt ttaaaaattg tatacttgtt
     6481 ctatattata gtcagtagtt ttaataggtc tttaataaga ttaaataatt aaataagtat
     6541 ctttttttgt tcttatttta cctataaaaa ttttcctaat taatctttca taaatatc
//
LOCUS       DAMJWO010000132         6582 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.137, whole genome shotgun sequence.
ACCESSION   DAMJWO010000132 DAMJWO010000000
VERSION     DAMJWO010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6582
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.137"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            86..1828
                     /locus_tag="PC366_003464"
     CDS             86..1828
                     /locus_tag="PC366_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M3"
                     /protein_id="HDF2578947.1"
                     /translation="MVKSKKKIFVFLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSDEFYSKEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGKDTFNYLKNIG
                     KLNSKEVEDLLKKEQDLVVKYEDLLAKSTVSIDGIEVDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKMQ
                     PSIDVCEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMSLNDINKLFFDLEEEYGVSNNILREKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQEDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQDGNLEEISSTLYD
                     YFGIDNPLELKNAS"
     gene            complement(1992..2186)
                     /locus_tag="PC366_003465"
     CDS             complement(1992..2186)
                     /locus_tag="PC366_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578948.1"
                     /translation="MKIITIGSSLITVLLFLSTMVCGFWIKNNKVTDASSIKFHMNSA
                     IFTGIFLLISTILLIIYIKK"
     gene            complement(2183..2764)
                     /locus_tag="PC366_003466"
     CDS             complement(2183..2764)
                     /locus_tag="PC366_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2578949.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCITNGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEDVDVR"
     gene            2932..3750
                     /locus_tag="PC366_003467"
     CDS             2932..3750
                     /locus_tag="PC366_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2578950.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNNTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IETTIKRIGGNDIMKNYDVTIKNFAPKYMMTLRRVIPTYQDEGMLWHQAFLETKDQNV
                     QIEPPKYSKAVFYDTGYKEDSVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGNWISDNNYDVDGPMFNIYHVSPGNDSNPDNWVTEVCFPVKKK"
     gene            4475..5296
                     /locus_tag="PC366_003468"
     CDS             4475..5296
                     /locus_tag="PC366_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallohydrolase"
                     /protein_id="HDF2578951.1"
                     /translation="MKLKIVGSGGMSIIPSSFCKCKICEEARQKGGRYERLGPSLYID
                     DIKMLIDTPEDITVACNRQKISEVKHISISHHDPDHVKGIRIVEKIGCDFITGENNPI
                     GFYALPEVIEDINRTNLDCLKYYGDVINCISINETSHVKINNFDIDLINNNPDRNITF
                     YVIKENEKKVIYACCNPKPFTHSDMYFDADVLIISLVSDDGILNDGTKLEDTPFKDEI
                     FTLDEIVEIKNYYRIKKIIITHIDEMWGKSYGYYSELEKKLDNIYFAYDGMEIIV"
     gene            complement(5606..6385)
                     /locus_tag="PC366_003469"
     CDS             complement(5606..6385)
                     /locus_tag="PC366_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HDF2578952.1"
                     /translation="MNYKKIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKVFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVVLGLICIPYMQKGSHIMNISSQASFQPLPYQNIYSSTKAFIRNY
                     TRALNVELKSKGINAIAVCPGWMSTNLFKRGIVVAEKGTKNFPGIVSPDVVAKKALKD
                     AKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
BASE COUNT         2471 a          886 c          840 g         2385 t
ORIGIN      
        1 tttatgttaa attttcttaa catgcatttt ttatatttaa tatagtaaaa taattaataa
       61 ctatatccat gattggagga tttttatggt taaatccaag aagaaaatat ttgtttttct
      121 aattttaatt gcagttttta ttatatttgc atcatacata agaaattata ctaatgatac
      181 aaaaaaagat tctgttagag gaactattcc ttttgaaaaa atggaatata agcgtcctaa
      241 tatacagtca atttgcgaaa acattaacaa gtgtaacgac aaacttttaa cagctaaaac
      301 agctaaggaa caattaaatt tatttaatga agttgataaa atttatcagg atttttacag
      361 tacacttact atagcaaaaa ttagaaataa catagattca tcagacgaat tttactctaa
      421 ggaatataag tatcttatga gtaaatcagt agatgttgac atgtcataca aagactttca
      481 agatagattt gtaacttcta aattctctaa agaattagaa aaagaacttg gaaaggatac
      541 atttaattat ctaaagaaca ttggaaaact taattctaaa gaagttgaag atttacttaa
      601 aaaagagcaa gacctagttg taaaatatga agacttatta gctaaatcta cagtatcaat
      661 agatggtata gaggtagact ttgaagaagc cttgtcaaga ccaaatctta gccctgaaga
      721 atatgtgaaa atttattcag attacttaaa aaaatacaat cctatatttg gtaacatatt
      781 cttagaactt atacagacaa gaactgaaat agcaagtaag caaggattta agaattatat
      841 agattatgcc tatatgaacc taaacaaaga ctattctcaa gaagaagcta aaaaatttag
      901 acaagatgta aaagattaca tagttccatt atatagagag atttcatcta aaccatctga
      961 ttcttctatt tatattaaag tatataaaaa tcgctcattt aggaagtttg ataaagtact
     1021 tgaagatata tctccaaaac taaaagagag cttcgactat atgaaaaaat atgacttgta
     1081 cgattattct tctggaaaaa acaaatcgcc tggaggatat actacttata taaataaata
     1141 taaagcacct ttcttgttta atacatggga caattctttt ttaggtgtta ctagttttgc
     1201 tcatgagttt ggtcattttt ataattacta caacagtatt aacttaaata ataagatgca
     1261 accaagtata gatgtatgtg aagttcattc aacatcttta gaaattctat tttataaata
     1321 ttttgatgat ttttttggta aacaatctga agctataaaa aaagaacact tatcgattgt
     1381 tttaaatact attattgatg cttgtcttta tgatgaattt caagaaatta tatacaagaa
     1441 tccatatatg agtctaaatg atatcaataa attgtttttt gatttagagg aagaatatgg
     1501 agtttccaat aatatactta gagaaaaaaa tgctcctttt tggatacttg tatctcataa
     1561 cttccaagtt cctttttatt acttgagtta tggtcttgca tctgatgtat cacttcagat
     1621 atggcaatta tcacaagaag attacagaaa agctgttgat gtatatatgg attttttaaa
     1681 tcaaaatact gatgctggat ttaaagatgt ggtagaaaag gtaaatttac aattaccttt
     1741 ccaagatgga aatttagagg aaataagctc tactttatat gattattttg gtatagataa
     1801 tccacttgaa ctaaaaaatg cttcttaatt tctaatactt tatactcact cttaagattt
     1861 agtattagat tgaaataagt gatatttttt cacacacaat taatgtttaa taaaattatg
     1921 tggtaaagta tcagaaattt ttaagactct tgtctttata atttctgata ctttatttat
     1981 taataatatt attatttttt tatatatata attaaaagga ttgtggaaat caataaaaat
     2041 atccctgtaa aaatagcact attcatatgg aacttaatag aacttgcatc tgttacctta
     2101 ttattcttaa tccagaaccc acaaaccata gttgaaagaa aaagtaaaac agtgataaga
     2161 cttgaaccaa tagttataat tttcatctta catcaacatc ctctccaata atattttcta
     2221 ttaaaatatc aatgaattta tctcgctcat atttattctt tatatttata ccactgtata
     2281 actgaaatga ttctgtagat aaagcagaaa tctgtattgg taaaataatt tgcagggcaa
     2341 tgattcttag actcatttca tcttttttat ttccaaaaat tttacgaagc atagggacaa
     2401 tatcaagttc tgcttgcata tctccattgg ttatacattg attcaacaca aaaggaagca
     2461 ctttttcata atgtaatcca gtatcacaca atttttttaa taaatttttc aaatcttcaa
     2521 taggtcttag agtatataca ctatcgtcat atagctctgc tattatattt gacatcacat
     2581 ctcctatggc agtactcaac aaattatcct ttgttttaaa atgataattt attaaaccaa
     2641 ctccaacatt tgcacgctca gcaatttttc taactgtaat ctcctcaata tcatctactt
     2701 catttaaaag attcaatgta acttcaatta tacgttctct agcatcttta tcattacttt
     2761 tcataataga cctccaaaat aattaacatt ttaggttctg aacatgttca gtataatatt
     2821 tttttcatca tatgtcaata taatttaatt ataattttag ttgactctaa cattatgata
     2881 tggtttatat taatattaag ctaaaagtac ctttataaag gagacaaaaa catgtttaag
     2941 ataggcgatt tttcaaagct aagtaaaatt agtattcgta tgttacgtca ttatgatgaa
     3001 ataggacttt taactccttc tcatacgaat aacactaatg gatatagata ctatagtgca
     3061 gaccaacttt ctactacaaa tagaatccat gcactaaaag atatgggctt tggcttgtat
     3121 tctataaaag aaattttgac agaatataac gataaagaaa gtcttataaa atatctaaat
     3181 atccaccatt ctcaagtaaa agaacaatta gaagatacac agaaaaaact attaaaaata
     3241 gaaaccacta ttaaaagaat tggaggaaat gatattatga aaaattatga tgtaactata
     3301 aagaattttg caccaaaata tatgatgaca cttagaaggg ttataccaac ttatcaagac
     3361 gaaggaatgt tatggcatca agcattttta gagacaaaag accagaatgt tcaaattgaa
     3421 cccccaaagt attctaaagc agtcttttat gatactggat ataaagaaga ttctgtagat
     3481 gttgaagtac aagttgctgt atctggaaag tataaagata ctgaacatgt taaatttaag
     3541 actgttccaa gtgtgactgc tgcaactgca attgttaatg gaaatttcaa tcaagttgca
     3601 gacgcttgtg aggctattgg taattggata tcagataata actatgatgt ggatggtcct
     3661 atgtttaata tttatcatgt aagtcctggc aacgatagta atcctgataa ttgggtaaca
     3721 gaggtatgct tcccagttaa aaagaagtaa tttttatatt aattggataa tattttaatt
     3781 tgttaaacaa attactttta gtattatgta taaataccta caatttaatt aggatattat
     3841 cttaatttgt taaacaaatt acttttagtg ttatgtataa atatctacaa tttaattagg
     3901 atattatctt aatttgtcag ataaatcact tgtgatgtta tgttcgaatg actagaattt
     3961 gattaggata ttatcttaat ttgtcagata aattacttat aagattatat acaaccctta
     4021 tactctagtt aaatatttga atcactaata taaattagtt tttaacaaaa caaagagtaa
     4081 agtacaaata attcctttgt actctactct ttttaacttt ctttgtataa taatacaatg
     4141 ataaatataa aaaattatat attccattct atagaaatat gttcaccaat aacatatatg
     4201 ttattaatca atattttata tcaaaattac atgaacctta tagaataatc atatcttatt
     4261 acaagaaaaa tgtcttatct atattgaata aagtcattcg gctcatatac aaagtcaatt
     4321 tcattgagaa atatttaata taatcttata aaaatttcat actattcttt catatttaca
     4381 tgtgatataa tttattaact cataattttg ttaatcagtt gtgattgtag attatttata
     4441 taatctaata tttttagaag gtggtgtaat aactttgaaa ttaaaaattg ttggtagtgg
     4501 cggtatgtca attattccaa gttcattttg taaatgcaaa atatgtgaag aagccaggca
     4561 aaaaggcgga agatatgaac gattaggacc aagtttatat attgatgata taaaaatgct
     4621 gatagacaca cctgaagata ttacagtagc ttgtaacaga caaaaaatat cggaagtaaa
     4681 acatatttca atttctcacc atgacccaga ccatgttaag ggtattagaa ttgtcgaaaa
     4741 aataggatgt gactttatca caggagaaaa taatccaatt ggcttttatg ctcttcctga
     4801 agtaattgaa gatataaacc gaacgaatct cgattgtctt aaatattatg gtgatgttat
     4861 aaattgcatt tctattaatg aaacttcgca tgtaaagata aataattttg atattgattt
     4921 gattaacaat aacccagaca ggaatataac cttctatgtt atcaaagaga atgaaaaaaa
     4981 agtcatatat gcctgctgta atcccaagcc atttactcat agtgatatgt actttgatgc
     5041 tgatgtttta ataataagtc tagtttctga tgatggtata ttaaatgatg gtacaaaact
     5101 tgaagacaca ccatttaaag atgaaatatt tactttagat gagattgttg aaattaaaaa
     5161 ctattataga attaaaaaga ttatcattac acatattgac gaaatgtggg gaaaatcata
     5221 tggttattac agtgaattag aaaagaaact tgataacatt tattttgcat atgatggtat
     5281 ggaaattata gtctaaatca ttaagtaata agcataatgc aaaataagaa aacttcaatt
     5341 taacagtata gttaaactat gtaatatcaa catatctcag tttttacaaa atatcatagt
     5401 atttatcttt ataaaatttc aagtcctaca tattttaata cttcaatatc taaataaagt
     5461 aaaatcaaaa atatattttt tatacattat agacggctta tcggcactag ataagccgtt
     5521 ttgtcacaat tattatttgc tcaacaaaac ttcttataat atataataga ttgaatctcc
     5581 aactgatact taattaccga aactcttatt ccttaatatg ttgttgcatt aaccaaacct
     5641 tcatcatcat tttttgtggc aatagttttg ctaataaatg actggatttt gtatttatac
     5701 catacacaga aatatcctta tttttctttg catccttcaa tgcttttttg gcaacaacgt
     5761 ctggagacac tatgcctggg aaattttttg tccctttttc agctacaact atacctctct
     5821 taaatagatt tgtactcatc caacctggac atacagcaat tgcatttatc cctttactct
     5881 taagttcaac atttaatgct cttgtataat ttcttataaa cgctttagtt gaactataaa
     5941 tattttgata tggcaatggc tggaatgatg cttgtgaaga aatattcata atatggcttc
     6001 ccttttgcat atatggaata catataagtc ccaatactac aacagcacta atatttaaat
     6061 caatcatatt aatagattca tctatactta aatcattgta tgaacagaat tttgcaaaac
     6121 cagcattgtt tataaggtat tttatacata cattttcttt acttaaaaat gtaccaattt
     6181 cttttacttc ttctattttt gataaatctt ttgaaaaaac ttttacctta cttccaaatt
     6241 catctactaa ttgatttaat ctcgccttgt ttcttgcaac tgcccatatt tctgttattt
     6301 cttcttcatt tattaataac tttagaaact ctttaccaaa accactatta gcacccgtta
     6361 taattgcaat cttcttataa ttcataatta ttctccttta ccataagttt atacgctcaa
     6421 actgtaaact tattttttac aaataaaaca ccctctattc agatgttata ttcatatcat
     6481 ttgagatatt atatttatat cattttcaat aattgttata tagcataaaa aatagtgtta
     6541 atattataga atcagtattg attatattta aaaagtagtg tt
//
LOCUS       DAMJWO010000133         6419 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.138, whole genome shotgun sequence.
ACCESSION   DAMJWO010000133 DAMJWO010000000
VERSION     DAMJWO010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6419
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.138"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            295..1239
                     /locus_tag="PC366_003470"
     CDS             295..1239
                     /locus_tag="PC366_003470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HDF2578953.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFTTINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     KNTVGIKEIRQIGCEYLGEASVEADREVVKLALKILEKYNNNFILEVGSSKYIHGLLE
                     ELNLNKNCENQIKNLLYTKNTHELKVYIEELKIKREVKELLSNILSLQGNLYNVIEKS
                     NKFYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSY
                     KEILSGGRYDSLTKEYGKEIPAIGFTLSVDELMKYVYK"
     gene            1261..1887
                     /locus_tag="PC366_003471"
     CDS             1261..1887
                     /locus_tag="PC366_003471"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HDF2578954.1"
                     /translation="MDYLTIALAKGRIEGESFKKFKKMGLGDSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            1921..2970
                     /gene="hisC"
                     /locus_tag="PC366_003472"
     CDS             1921..2970
                     /gene="hisC"
                     /locus_tag="PC366_003472"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HDF2578955.1"
                     /translation="MREKESIRELRGYEPNHVNCKVKLDANEGSKRLFKYLIKEISDS
                     DIDLNLYPEDSYSDLKESIIDYINISGVNKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVINIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKREEIIKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEEREVLYE
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     SMFVGAIRDILKKEK"
     gene            2973..3551
                     /gene="hisB"
                     /locus_tag="PC366_003473"
     CDS             2973..3551
                     /gene="hisB"
                     /locus_tag="PC366_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HDF2578956.1"
                     /translation="MRIWKVERNTFETQILVELNIDGSGKAEIDTGIGFLDHMLTLMS
                     FHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESL
                     SMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            3553..4158
                     /gene="hisH"
                     /locus_tag="PC366_003474"
     CDS             3553..4158
                     /gene="hisH"
                     /locus_tag="PC366_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HDF2578957.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSDIDEIKQADSLILP
                     GVGAFRDSISALDKLGLIPIIKEHVSKGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDITLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELVAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            4155..4877
                     /gene="hisA"
                     /locus_tag="PC366_003475"
     CDS             4155..4877
                     /gene="hisA"
                     /locus_tag="PC366_003475"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HDF2578958.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGINTKIIEDIANNIDIPIQVGGGVRDKGKVKSLINAGVTRVIL
                     GSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSDVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFDIYERIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            4859..5617
                     /gene="hisF"
                     /locus_tag="PC366_003476"
     CDS             4859..5617
                     /gene="hisF"
                     /locus_tag="PC366_003476"
                     /EC_number="4.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HDF2578959.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKNMGVEVRL"
     gene            5645..6313
                     /locus_tag="PC366_003477"
     CDS             5645..6313
                     /locus_tag="PC366_003477"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HDF2578960.1"
                     /translation="MDNKCNNVYSDEVEEFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     YMNKDAIKKTLKDKVACYFSRSRQKLWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDSSKMEPEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KRRK"
BASE COUNT         2617 a          541 c         1266 g         1995 t
ORIGIN      
        1 ctgtaaattt agaatattaa taaaaattat ttgggaggaa attatcatgg tgagattaaa
       61 tatagtaaaa ttaaatacaa aattaaatca tcaccatcat catagattaa agggattgta
      121 atatgaaatt aattcataga cacaagccct gtttttagtg taattggtct tgtatctatg
      181 atgggaagta attttaggag aaaattatag ccatataggt ataaagccta tatggctttt
      241 ttattgtttt aaatttgcaa atataagagt aaatttaatg aagagggtga gaatgtgaaa
      301 tttttgagga ttgaagatga agttatttat tctaaaaaaa gatataaatt aaaaagggaa
      361 atagataaac tttttttgga tgaagaatat tttcaaatag aaccacaatt atttgaagaa
      421 tatgatgaat ttacaactat aaataataaa attccagaag aatctatggt aaaggttgta
      481 aatggaaaag taatggtact tagagctgat ataactacaa gtataataaa aagccttgta
      541 ccaagatggg aagatggttt aaagcttaag cttttttata attcatcaat atataaaaat
      601 aaaaatacag ttggaataaa agagataaga caaataggtt gcgagtatct aggagaagcc
      661 tctgtagaag cagatagaga agtagtgaaa ttagctctta agatacttga aaaatacaat
      721 aataatttta ttttagaggt tgggagtagc aagtatattc atggtttgtt agaagaatta
      781 aatttaaata agaattgtga aaatcaaatt aaaaatttac tatatacgaa gaacactcat
      841 gaattaaaag tatatattga agaactgaaa attaagcgtg aagtaaaaga gctattatca
      901 aatattttaa gcttgcaagg gaatttatac aacgttattg aaaaatcaaa caagttctat
      961 tgtaataata agatgaagca agctcttgaa gaattaaagc aagtaaataa tttaattgag
     1021 gaatgtaatt ttttagataa ggctagattt gatttatcaa tgattactat gcttgactat
     1081 tatgaaggaa ttatgtttag aggatactac ccaaactcat ataaagaaat tcttagtggt
     1141 ggaagatatg attctttaac taaagagtat ggaaaagaaa ttccagccat tggatttaca
     1201 ctaagtgttg atgagttaat gaagtatgta tataagtaaa gtttagaagg agggattgct
     1261 ttggattatt tgactatagc actagcaaaa ggacgaattg aaggggaatc atttaaaaaa
     1321 tttaaaaaaa tgggtctagg agatagtata gacacagata cgagaaaact aatttttaaa
     1381 gatgaagaaa ataaaattat atatatacat gtaaagccat cagatgtagt tacatatgtt
     1441 gaaaaaggag tcgctgacct tggtatagca ggtaaagata ctattttaga gaatgagaca
     1501 gatgtatatg aaatatatga tttaggtttt ggaaaatgta aatttgctgt agcaggatta
     1561 aagggagata gcatatatag agaagatgaa tatctaaaag tggcaacaaa gtatcccaat
     1621 atagcaaaaa agtattttaa agagaaaggt caaaaaattg aaataataaa attaaatggt
     1681 tctgtagaac tagctccaat agtagggttg tcagatgtaa ttgtagatat agttgagact
     1741 ggcaatacac ttaaagcaaa tggtcttgaa atattagaag acatatgtaa tataagtgct
     1801 agaattatat caaatagagc tagctataga tttaaatatg aacaaattca gaatataatt
     1861 cgtttatttg aagaacttga taattaaaat ataattgaac tttataagga gggatttaag
     1921 ttgagagaaa aagaaagtat aagagagtta aggggatatg aaccaaatca cgtaaactgt
     1981 aaagtaaaac ttgatgcaaa tgaaggaagt aagaggttgt ttaaatacct tattaaagaa
     2041 atttcagata gtgatataga tttaaattta tatcctgaag attcttatag tgatttgaaa
     2101 gaatctataa tagattacat aaatatttct ggagtaaata agaaaaatct tctagtagga
     2161 aacggttcaa gtgaaataat tgatttaata atacatactt ttgtagataa agatgaagta
     2221 atattgagtt tctctccaag ttttagtatg tattctatat atagtcagat aaatgggtct
     2281 aaatttatag gtgttgaaag tgatgaaaat ttagttataa atatagataa tgtgattgaa
     2341 aaagtaaagg agaataatcc taaaatagta attgtatgta atcctaataa tccaactgga
     2401 acaatattaa agagggaaga gataataaag cttttagatt caactaatag tctagtggtt
     2461 ttagatgaag catatatgga ttttggagaa gaaagcatgt taagtgatgt ttttaagtat
     2521 gataatctaa tagttcttag aactttatca aaggcatttg gattggctgg aataagaaca
     2581 ggatatatgt tatctaatag tagtttaata aattctgttg agaaagtaag acctccatat
     2641 aatttaaatt cattatcaga ctttattgct acaagagcac ttagaaataa agatgtggta
     2701 aaggcttata taaaggaagt aaaagaggaa agagaagttt tatatgaaga aatgattggt
     2761 atgggaatta aagcatacaa atcacaagca aattttatat tattttattc tgaaatcgaa
     2821 aatttatcac aaaaacttat tgatagagga gttttaataa gaaaatttgg tggaaagtta
     2881 gaaaattatt acagagttac aattggtgat aaagaagaaa attctatgtt tgttggagct
     2941 ataagagata ttttgaaaaa ggagaaatag gtatgagaat ttggaaggta gaaagaaata
     3001 cttttgaaac acagatttta gtagaattaa atattgatgg ttctggtaaa gctgaaatag
     3061 atactggaat aggattttta gaccatatgc ttaccttaat gtcatttcat ggcaagttcg
     3121 atttaaaagt gatttgtaag ggtgatacat atgtagatga ccaccatagt gtagaagata
     3181 taggtatagc tataggtgaa gcatttaaaa atgcactagg tgacaaaaaa ggaatacgaa
     3241 gatattctaa tatctatata cctatggatg aatctctatc aatggtagca atagatataa
     3301 gtaatagacc ttatcttgta tttaatgcta aatttgatac ccaaatgatt ggtagtatga
     3361 gtactcaatg ctttaaagaa ttttttagag cttttgtaaa tgaatcgaga gtaacattac
     3421 atatcaatct cttatatggg gaaaatgacc atcataagat agaaagtatt tttaaagcat
     3481 ttgcaagagc tttaaaagag ggtagtgaaa tagtttctaa tgagatagca tcttcaaagg
     3541 gggttttgta gaatgaatat aatagtagac tatggtcttg gaaatataga ttctgtgtct
     3601 aggggtttta gaaaagctgg aatagaaact aaaatttcta gtgatataga tgaaataaaa
     3661 caggcagatt cacttatact tccaggtgtt ggagctttta gagattctat aagtgcctta
     3721 gataaactag gattgatacc aataataaag gagcatgttt ctaagggtaa atttatgata
     3781 ggtatatgtc taggaatgca attactttat gaaaaaagtt atgagtatgg agaatatgaa
     3841 ggattaggac ttataaaagg aagtattgat aaactggata taactttaaa agtgccacat
     3901 atgggatgga ataatctaaa atttaataag gcaaatgatg atatacttaa atatataaac
     3961 gaagatgatt atgtatactt cgttcactca tattatgcaa attcatcaaa tgaagaacta
     4021 gttgcatttt cagaatatga aaagaaaatc cctgctattg ttagaaaagg caatgtatat
     4081 ggtatacaat ttcatcctga aaaaagtgga gaagtagggt taaatatatt aagagcatat
     4141 ggggagatga taaaatgata atatttccag caatagatat aaaagataat aagtgtgtaa
     4201 gactcacaca aggagaattt gacaaagtaa atgtatatta tgataatcca ttagaagtag
     4261 catataaatg gaaaaatgaa ggagcagaat atatacatat agtagattta aatggtgcta
     4321 gaagtgaatt tggtataaat acaaaaataa ttgaggatat agcaaacaat atagatatac
     4381 ctattcaagt tggtggtgga gttagagata agggaaaagt caaaagttta ataaatgctg
     4441 gtgttactag agtaatatta ggtagtatag cgattgaaaa tttgaatttg gttgaagaat
     4501 tggtcaatga atataaagag aaaattgtag tttctataga cgctaaagat ggaaaagtag
     4561 cagttagggg atgggaagtt gtaagcgatg tagactcatt aacattatgt aaacaacttg
     4621 aaaagatagg tgtacaaact attgtttata cagatatatc aaaagatggg atgttgcaag
     4681 ggccaaattt tgacatatat gaaagaatag caaaggaaac gtcattaaat gttattgctt
     4741 ctggaggcgt aacttctata gaagacgtaa aaagactaaa agctatgaac ttatatggtg
     4801 caataatagg taaagcgctt tatgataaaa agatagactt taaggaggca caacaattat
     4861 gcttactagg agaataatac cttgtctaga tgtgagaaat ggaagagttg taaagggaaa
     4921 aaaatttaaa gatatagtag atgttgatag tccagaagta cttggaaaat tttatagtga
     4981 ttgtggtgca gatgaacttg tattctatga tataactgca tcaaatgaag agagaaagac
     5041 atctttagaa tttgtgacaa aagttgcaga aaatataaat ataccatttt gtgttggtgg
     5101 aggagtaaat aaattagaag atttcactga tattttaaga aaaggtgctg ataaggtttc
     5161 tataaattca tcagcagtca aaaatcctga attaataagg gaagcttcat taaaatttgg
     5221 agcacaatgt gttgttttat cgatagatgc aaagaaaaat gaagagggtt catggagcgt
     5281 atacgtaaaa ggtggaagag aaaaaactaa tctggatgca attgaatggg ctgttaaagg
     5341 tgtagaactt ggagcaggag aaattgttgt aaatagtatg gacgaagatg gaatgaaaaa
     5401 tggatatgat atagaattat tatcaaagat aacttcttta gtaaatgtac ctgtcatagc
     5461 atctggaggc gctggaaaaa aggaagattt ttatgaggca gttaataaat ctaatgtaga
     5521 tggaatttta gcagcatctg tttttcattt tggcgagata aaaataaacg atttaaagaa
     5581 atatttaaaa aacatgggtg tagaagtaag attataagtt aaatactaaa aggagattag
     5641 aaatatggat aataagtgta acaatgtata cagtgatgaa gtagaggaat ttataagaag
     5701 tataaagttt gatgataaag ggttagtccc tgttgttgtt caagaggtag ttagtaaaga
     5761 tgtactgatg ttagcatata tgaataaaga tgctataaag aaaaccttaa aagataaagt
     5821 agcttgctat tttagtagaa gtagacaaaa actttgggtt aaaggtgaga catctggtaa
     5881 tactcaaaaa gtagttaaga tgtcttatga ttgtgatgta gatactatac tactttttgt
     5941 tgaacaaact ggtgtagctt gtcatacagg caattattct tgtttttaca gagacttgtt
     6001 tgatgatagt tcaaaaatgg agcctgaagt acaaacaaat atattgaaag aattatatga
     6061 tttaatcaat gaaagaaaaa ataatccagt tgaaggttct tatactaatt atctttttga
     6121 aaaaggaata gataagattc ttaaaaaagt aggtgaagag agtagtgagg taattatagc
     6181 atcaaaaaat accgataaaa gtgaacttat ttacgaaatt agcgatttag tgtatcatac
     6241 attggtttta atgatagaaa aaggtgttga aattgatgaa ataaaaaaag aattacttaa
     6301 aagaagaaaa tagaatagga tagattaatg gtaataagaa aatataccgc ttttaataaa
     6361 aagtggtata ttttttattt tatattttcg atttatagaa taatatttaa attacttga
//
LOCUS       DAMJWO010000134         6255 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.139, whole genome shotgun sequence.
ACCESSION   DAMJWO010000134 DAMJWO010000000
VERSION     DAMJWO010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6255
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.139"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(112..327)
                     /locus_tag="PC366_003478"
     CDS             complement(112..327)
                     /locus_tag="PC366_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578961.1"
                     /translation="MHINQTGFISNGLGIKQQQKKEPTSNSFSYNAPSSWKPVGRDSV
                     QYNCGFELIATLVREGSSWAFNFIVQP"
     gene            complement(510..854)
                     /locus_tag="PC366_003479"
     CDS             complement(510..854)
                     /locus_tag="PC366_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578962.1"
                     /translation="MNYRLKKSVTTILSLLIMTILLPTNASASKVEDSSMKVMYSEKQ
                     VTDMDKLYDMAKNGITDVKSSNEKGIIKNARTGESIYVDSISTTQLLEVKQSKNLTSK
                     IYSKTVFLILIQ"
     gene            981..1364
                     /locus_tag="PC366_003480"
     CDS             981..1364
                     /locus_tag="PC366_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578963.1"
                     /translation="MRKKFFIGILIVLIISVIAILNIKNDKNVFIGESENWKAKFVTT
                     EGHSKLEIKYKNSKDVVEQKFNYSYQFIDGEDAVVVVKNEILEAGQEKAIKIQRPGLY
                     SNRESSYKLIISWNGNEETINLKKK"
     gene            complement(2573..2824)
                     /locus_tag="PC366_003481"
     CDS             complement(2573..2824)
                     /locus_tag="PC366_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578964.1"
                     /translation="MSSYFITRGDVMKILQQFKPYKYDKEKNIEYDEKIIANQNTEVY
                     IVYPRISDEENRRRWEEFNEVAKEVAINIAMKKVETVES"
     gene            complement(3070..3225)
                     /locus_tag="PC366_003482"
     CDS             complement(3070..3225)
                     /locus_tag="PC366_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulator"
                     /protein_id="HDF2578965.1"
                     /translation="MALDVKIEVKIIKDVVILNIIHWKKETSLLTVKIARGQGDLSYV
                     KYFTNES"
     repeat_region   4442..5399
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=4442..4470
                     /rpt_unit_seq="ctttacataccacttagttaatataaaac"
BASE COUNT         2228 a          883 c          637 g         2507 t
ORIGIN      
        1 caattgttac tataacgtag gaattatctt taaaaacaca aattaattta cattctctaa
       61 ttttaaagta tatgtatatc tttgatttta ataaaattca cttaaaatat tttaaggttg
      121 aacaatgaaa ttgaatgccc aagaacttcc ttctcttact aatgttgcaa ttaattcaaa
      181 cccacaattg tattgaactg aatctctacc tactggtttc caactagaag gtgcattata
      241 tgagaaagaa tttgatgttg gctctttctt ttgttgctgc ttaattccta gcccattaga
      301 aataaatcca gtttgattta tatgcaccct tctatttgtt acacgaatct ggccgtctgc
      361 aatagaccag tttccagaaa ctttactaac ggaaatatat tgaaatgctc catctccttt
      421 tgatattgta tatgtaactg taccagatgc ttttacacca ccagttttat cccatccatc
      481 ttctgatata cttgcttttc taagaggctt tattgtatta gtatcaaaaa aactgtctta
      541 gaatatatct ttgatgttaa atttttagat tgtttaactt ctaataattg agttgttgat
      601 atagaatcaa cgtatatgga ctctcctgtt cttgcatttt tgattatacc tttttcattg
      661 gaacttttaa catcagtaat tccattttta gccatatcgt ataatttgtc catgtctgtt
      721 acttgtttct ctgaatacat tactttcata gatgaatctt ctaccttact agcacttgca
      781 tttgttggta atagtattgt cattatgagt aaagataaaa tagttgttac agattttttt
      841 aacctataat tcatattaat ccttactttt tatttgttat aacagacatt ctattgtaat
      901 agaatataaa tccacaatat ttttaaaatt agtattgaat aactattctc atgttataat
      961 tattcaaagg agggattgat atgaggaaaa aattttttat aggtattctt atagttttaa
     1021 taatctctgt gatagctata cttaatataa aaaatgataa aaatgtcttt attggagaat
     1081 cagaaaattg gaaagctaaa tttgtaacta ctgaaggaca ctcaaaatta gaaataaaat
     1141 ataaaaatag taaagatgta gttgaacaaa aatttaatta ttcctatcaa tttatagatg
     1201 gtgaagatgc agttgtagtt gtaaaaaatg aaattttaga agcaggtcaa gaaaaagcaa
     1261 taaaaataca aagaccaggt ctttattcaa atagagaatc tagttacaag ctaattatat
     1321 cttggaatgg aaatgaggaa actataaact tgaaaaagaa ataaccatat tatcaatttt
     1381 taaaaaatta ttattcaaat tcttataaaa agagtgttta gaaaaatgaa acactctttt
     1441 ttgtataagt ttttgaaaac tataaatgaa atatatcaaa atcgttcgaa aaattactga
     1501 aataaactct taaatatatt ataaattaag gtatattata catgaattta ttgggagttt
     1561 atgagtttta aaattggaaa ccaaacaata agggctaaaa atactttaag gaaaatatat
     1621 aaagttctat aaattatcaa aaatatttcg caaaaattga taattattac aaataaattg
     1681 ataatactaa taatattaga aatatcgaaa ttgaacaaac taggattaaa gctcaattag
     1741 aaaaatccac taatcctgag aatgctttgt tattctcatt tattactgtt gttttttcat
     1801 tatttgctaa tttatttttc agttcattaa atgttaaata taactctata aatttaattt
     1861 tacagttaat atgtattata gttcttatat ttatatatat taatacattt ttatatcgcc
     1921 tcttcaattt gagccccatc attatataaa attaacctac ttgatatctt aatttaatat
     1981 atgtacacta ttcatatctt aatagtcaat attattcatt tttaatagct ctttttagat
     2041 gtcagaatta ttatattttg aaatttatta aatttttgca ttaaaaaaac tagaaattaa
     2101 tttaagtctt gaattactta taactttcta cgtatctacc tttatattct tactctgatt
     2161 ttatatctaa tattaactct tcatcaaagc tattaaatat acctctaatt gagtcaatta
     2221 tttcacttac ttcaccttta atttttatat taacttcaac catttcaaat ctcatctttt
     2281 tatcttataa tttctataag tttttttatt tattgtgttg cttactttga ccagcacttt
     2341 tttatttaat agtctaaatg atatttttta ccagttttaa tatccttaaa tactatattt
     2401 actaaaaact tataatttct tttaatacat tcttattact aataacaata ctcaacaatt
     2461 ttatcgcctt ttttcaaata tgatttaact tttttattcc taattattta aaaatagttg
     2521 tccaattttc ttctatgaga aagtgctaag tattagcaac ttctctattc tcttaacttt
     2581 ctactgtctc aactttcttc atagctatat taatagctac ttctttagct acttcattga
     2641 actcttccca tcttctccta ttttcttcat cagatatacg tggatatact atataaactt
     2701 ctgtgttttg attagctata attttttcat catattctat atttttttct ttatcatatt
     2761 tgtatggttt aaattgttgt agtattttca taacatcacc ccttgttata aaatatgaac
     2821 tcataaactt gtcttatact tatttaattg ttacaatttt tacttaaaat cactttatat
     2881 tctatatttt aaagctaaat cctttacaaa agtaacatat tcttctataa gtttcttatc
     2941 ctcttatata gtatctagtt tgtttaactt atctctttta aacttacata cgccttcttc
     3001 tgccattcgt cttttattaa ttgttaacat tgtttcaaga gacacaccaa aactcttgtt
     3061 aagaagctct tagctctcat tagtaaaata ttttacataa cttaaatcac cttgacctct
     3121 agcaatttta actgttaata gacttgtttc ttttttccaa tgtattatat ttaatataac
     3181 aacatctttt attattttaa cttctatttt tacatctaat gccatattat tgctttatta
     3241 atttgtatcc ttaaatctta aattttctat taatacatct tctatacagc ttagtttctc
     3301 tcgcttaatc ttgaaatata ttttctctaa attgtcaaat tgttcccaag ttttatcaat
     3361 atctaatatt ttgcagtgtc tatttgcaca tctttcgatc caaaggtata attgactaga
     3421 atgttttgaa atcaactgac tattagtagg ttagttctta aattctttca aatactcgaa
     3481 ttgtaataaa acataattta cattctcttt atttctattg aagttagttt atatattgtt
     3541 tacatcattt tcatatatat ctgctagttg ctatgcattt aaaattctct tattatttct
     3601 ttatattact tgtaaattat tcatcctcat catcctctta attaaatttc tatcttagaa
     3661 atttaatttg taaaaaaatt ttctatatca taatcaagta tcttagatag tttataggta
     3721 acatatcaac tctaattgaa tattacccct tcctgtactt aaaataagtt gatgcatttt
     3781 taaaacctaa ctcttttgca acactttgta agtataaatt ttatgtatgt cttctttttt
     3841 ataaaatcat agtgtatctt tttcatatat tcaccttaat tgctatattt caataacaat
     3901 atttccaaaa cagaaatttt tcgaggtaat tatgtataga tgtaaatcaa agaattaaat
     3961 atactaggga aaatatgaat agttctcaaa aagaattgct tgaaaaaaca aatataaata
     4021 caagtgttat gaatagaatc tggtgaaaga ccaacaagag acgatgggtt aataatattt
     4081 gctaaaattt ttggtttata tactgattat gttcttggtt tatcagatac agaaaaacta
     4141 aatattggca attaaaactg aattgattgt attatatgtg tgatgaatat aaatatagaa
     4201 ttttttgaga agcttgaaat agcttagaaa aaataagaga ttcactcaag aataagttac
     4261 taaagattaa aaaataacaa aagtatctac taaaggatat gaaaatggtt taagagagtt
     4321 aagtctggaa atatttatgt gtattcttta aataaaaatt tattttttaa atgataatta
     4381 aatttttact gatatggcta tgcttttaaa agtcataacc ttattttgat attagatctg
     4441 tctttacata ccacttagtt aatataaaac taaatatagc ttgtaactcc tttgatgcac
     4501 ttaaaagctt tacataccac ttagttaata taaaacgaat ttagctatag aagcatcaaa
     4561 ttgtggcaca gcactttaca taccacttag ttaatataaa acctttaaag acaaaacgtc
     4621 gtataattaa atcatagcaa ctttacatac cacttagtta atataaaacc ttataattct
     4681 ttaagtacta gactgagcaa tttaatcttt acataccact tagttaatat aaaaccatcc
     4741 cattcagcaa caacagtcgc taaatcttct gcctttacat accacttagt taatataaaa
     4801 cttttagtat attttttagg tctgccctct ttaaaactct ttacatacca cttagttaat
     4861 ataaaacacg aggttatagt taattttgtc gtgggagttt ataactttac ataccactta
     4921 gttaatataa aacaatttat atatatatat atatatatta aagtcagacc cctttacata
     4981 ccacttagtt aatataaaac ttgttgttca gcattagcaa tcatatcatc tattcctttc
     5041 tttacatacc acttagttaa tataaaacct gtaccatcag agacagtcat taaaagattt
     5101 ataaacttta cataccactt agttaatata aaacttataa attgtctctg tacccatttt
     5161 attcaatgtc gtactttaca taccacttag ttaatataaa accatgaaaa aatgggtaat
     5221 tcaaactctt ttattttctt tacataccac ttagttaata taaaacgttg gagaaaataa
     5281 tccttcttat gatttgccaa gcggctttac ataccactta gttaatataa aaccagcgga
     5341 tgaattattt atgttaattg gagatggaga ctttacatac cacttagtta atataaaacc
     5401 ccaaaataaa ttgagtattt ccaacactta catctataca attctctcaa atttgcagtg
     5461 aaccatgagt agtgcaaatg ataacattta tcacataccc tcaatgcctt atatttcaac
     5521 tgttaggccc tattttatca aaaatatcgc tcactgcaaa actatttata attttataat
     5581 attatgaata tattattttt aaatatctgt accaatttgt agtataataa aatcaagaaa
     5641 ataatttact cctataaaga gtgattattt ttaagtgaaa atattatttt tttaaatcat
     5701 ccttattggc gtttgggaga tttttatttt atcataaata taaactgata taacaccagc
     5761 tgacatgctt gctgctttcg attattattc ttgctacaat tattataaca tataaaactt
     5821 acttattttt accaaatatt ttatacaaac aataaatatt aacttatgaa atatctactc
     5881 atttacagat atttcataag ttaatagctc tataataaaa tttttatcat tgtttataaa
     5941 aaattttact ttgcattttt ttataaacaa cagttttatt tataatgttt tgtggtataa
     6001 taaaagcaag aagaactaca atctattttg cgttagagtg gagttcatca taaacagagt
     6061 ttattttttg gatttaaata taaatttaaa ttcaactcgt aagtcactct ttgtgctgaa
     6121 ctatacccac tgttttatac agttaaaaca tgtaaaagtg gttataaagt actagtgtca
     6181 atcattagta ctttttttat tatattcata taattaatag ctatatttta aagtttacta
     6241 tctaaaaaat agcac
//
LOCUS       DAMJWO010000135         6212 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.140, whole genome shotgun sequence.
ACCESSION   DAMJWO010000135 DAMJWO010000000
VERSION     DAMJWO010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6212
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.140"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            175..1197
                     /locus_tag="PC366_003483"
     CDS             175..1197
                     /locus_tag="PC366_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDF2578966.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSLL"
     gene            1257..2264
                     /gene="gap"
                     /locus_tag="PC366_003484"
     CDS             1257..2264
                     /gene="gap"
                     /locus_tag="PC366_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDF2578967.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            2486..3688
                     /locus_tag="PC366_003485"
     CDS             2486..3688
                     /locus_tag="PC366_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HDF2578968.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEKMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKANNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEDYMGLDMGPKTIANFVKTIKESKTVVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            3714..4457
                     /locus_tag="PC366_003486"
     CDS             3714..4457
                     /locus_tag="PC366_003486"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HDF2578969.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCKVQVEKALENVLKDDLSK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            4466..5998
                     /locus_tag="PC366_003487"
     CDS             4466..5998
                     /locus_tag="PC366_003487"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003228330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HDF2578970.1"
                     /translation="MMKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTL
                     INASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFANKVLCEAMD
                     NAKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALE
                     YAKEVQASMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKANSIEEAI
                     QNSYDDGKNDEFIMPTVIMKDDKPVGSIKENDSIIFFNFRPDRARQITRALVCEEFDG
                     FKREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAH
                     VTFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVL
                     NFANPDMVGHTGSIEAAIKAVETVDTCVGKLIDKIVELGGSAIITADHGNAEYMLDPE
                     TGKTVTAHSINPVPFIVVGQEYESAKLLDGGRLSDIAPTVLDMMKLEKPEEMTGHSLI
                     SK"
BASE COUNT         2472 a          726 c         1253 g         1761 t
ORIGIN      
        1 atactgtgat ttgaaaatgg tggagaaata ttttataaaa taaaaaaata aaaaagtttt
       61 tgaaaaacta ttgaaatcta tacgcaaatc ctataaaata aaaatatctt gtgggactta
      121 aataaacact agggacaaaa aaagtcccga aaggaaagca ataaggagta tgttatgaag
      181 aacttattag aaattcaaaa gaaattgatt ccacaggcaa ttgaacttat ggaaagaaga
      241 tactctattt taagacaaat atctttaagt gaaccaatag gtaggagaac attatcaaat
      301 gtattagaga ttagtgaaag aataatcagg tcagaaactg agtttttaaa agaacaagga
      361 cttatagacg tagctgtatc tgggatgact atcactaaag aaggttctga tttgttagat
      421 aaacttaagg acatcatgag tgacatcatg ggattgtcta agttacaaga tagagtcaga
      481 gaaaagcttg gaataaaaag ggtaatacta gttcctggaa gctgtgatga aaatggaagt
      541 ttactaaaag atgtaactag atatggatgc gagtatttct taggcatttt aaaagatgga
      601 gatatcgttt caataacagg aggaagcact atgttggagt tttcaaacgt tattaaaact
      661 gataagagat atccaaactc tacaatagtt ccagctagag gaagtatggg aactgatgta
      721 gagatgcaat ctaacaatat agttgcttca ataagtaaga aattacattc taattgcaaa
      781 cttttacata taccagatga gttggatgaa agtgcaatga aaactcttag ccaagtgcca
      841 gagattaaga caactttgga gtatattaaa agaacagaca ttttagtttt tagtataggt
      901 agagcagatg tcatggcaaa gagaagaaaa cttccagaag acaaggttga tgagatatta
      961 tctaaaaatg cagttggaga agcatttgga tattatttca acaaagatgg agaaatagtt
     1021 tacaaactga acactgttgg aattgattta gaaacagtta aacaagtaaa agaaactatt
     1081 gcaatctttg cagggactga aaaagtagaa gccttattag ctatatcaaa tatgcataaa
     1141 aacatggttc ttgtaacaga tgaagaaagt gcttataaga tattgtcatt attataaaag
     1201 tcaagaccta gcacagagct agaaaacata catttacttt ataggaggta gcgaaaatgg
     1261 ttaaagtagc tataaatgga tttggaagaa taggaagatt agcattaaga aaaatgatgg
     1321 agcaacaaga taagttcgaa gttgttgcaa taaacgactt aacagacgct aaaatgttag
     1381 ctcatttatt taaatatgat acagctcaag gaagatttaa cggagaaata gaagttaaag
     1441 aaggtgcttt tgtagtaaac ggaaaagaaa taaaagtaac agcagaaaga aatcctgctg
     1501 acctaccatg ggctgaatta ggagtagata tagtattaga atgtacagga ttctttacat
     1561 ctaaagataa agctgaagct catatacaag caggggctaa gaaagttgtt atatctgcac
     1621 cagctactgg agatttaaaa acaatagtat tcaacacaaa cagtgacata ttagatggtt
     1681 ctgaaacagt tatatcagga gcttcttgta ctactaactg tttagctcca atggctaaag
     1741 tattaaatga taaatacggt atagaaaaag gattaatgac tactatacat gcatacacta
     1801 atgaccaaaa tactttagat ggtcctcatc caaaaggtga tttaagaaga gctagagctg
     1861 ctgctggaaa catagttcca aacactacag gagctgcaaa agcaataggc ttagtaatac
     1921 cttcattaaa aggaaaatta gatggggcag cacaaagagt accagttgta actggttcaa
     1981 taactgaatt agtttgtaca ttaggaaaaa atgttacagt tgaagaaata aatgcagcta
     2041 tgaaagaagc ttcaaacgaa tctttcggat atactgaaga aatgttagta tcttctgaca
     2101 taatcggaat aagctacggt tcattatttg acgctactca aacaaaagtt atggaagtag
     2161 atggaaaaca attagttaaa gttgtttctt ggtatgataa tgaaatgtct tatacttctc
     2221 aattaataag aactttagga tactttgcac aattagcaaa atagtcagtt ttgagaaaat
     2281 agaaaagtag attgacaaag tccgagtttg tagtttaata ctacggactc aggacttttt
     2341 ttaagaaaaa atatataaaa tacacctaaa taatgttaca tactatatat aaaaatatga
     2401 taatatgata tatttaatag ggtaaaagta tgtactatat tatacttggc aataaaaaat
     2461 tactttatta aaaggagaga tatttatgtc aatgcttaac aaaaaaacta tagaagatat
     2521 tgatgtgtgc ggaaaaaaag tattagtaag atgtgacttt aatgtgccat tacaagatgg
     2581 tgtaattact gatgaaaata gattgaacgg agctttacca actattcaat atttaatttc
     2641 taaaggggca aaagttatat tatgctctca cttaggaaag ccaaaaggag aagctaaacc
     2701 agaattatct ttagcaccag tagcaaagag attatctgag atgttaggaa aagaagttgt
     2761 atttgcagca gacgataatg ttgtaggaga aaatgcaaag aaagcaactg aaaaaatgga
     2821 aaacggagat gtagtattat tagaaaatac tagatataga aaagaagaaa ctaaaaacga
     2881 agagaatttc tctaaagaac tagcatcact tgctgaaata tttgtaaatg atgcatttgg
     2941 aactgctcat agagcacatt gctcaacagt tggtgcaggc gagtttttac aagagagagt
     3001 ttgtggatac ttaattcaaa aagaattaaa attcttagga gaagctgttg caaaccctgt
     3061 aagaccattt acagctatac ttggaggagc taaagtttct gataaattag ctgttataaa
     3121 cgaattatta gaaaaagttg ataatctaat aataggtgga ggaatggctt atacattctt
     3181 aaaagctcag ggttatgaag taggaacttc tttacttgaa atagataaag ttgaatatgc
     3241 taaagaaatg atggaaaaag ctaataataa gggtgttaac ttattattac cagtagacgt
     3301 tgttatggca gaccactttg caccagatgc tactccaata gtaacagaag atgctaatgt
     3361 aaaagaagat tacatgggac tagatatggg acctaagact atagcaaact ttgtaaaaac
     3421 tataaaagaa tcaaaaactg tagtatggaa tgggccaatg ggagtatttg aatttgaaaa
     3481 ctttgcaaat ggtacattat cagtagctag agctatggca gagttgactg atgcaactac
     3541 tgtaattggc ggtggagata gtgcagcagc agttaatcaa ttaggatttg gtgacaagat
     3601 gactcacgta tcaacaggtg gaggagcatc actagaattt ttagaaggta aagaattacc
     3661 aggtattgca gcattagata ataaataaac taatatatag aggagattgt aaaatgagaa
     3721 aacctataat tgcaggaaac tggaaaatgc ataaaacaat aaaagaagct ttagaatttg
     3781 taaatgaagt taaagataaa gtaaattctg ataaagtaga agctgttata tgtgcaccat
     3841 ttactttatt aaaggattta aaagaagcta ctaagggtac aaatataaag ataggtgctc
     3901 aaaatatgca ctttgaagaa aaaggagcat ttacaggaga agtttcacct cttatgttaa
     3961 aagaaataga tatggactat gttgtaatag gacattcaga aagaagacaa tacttcaatg
     4021 aaactgatga aactgtaaac aagaaagttt taaaagcatt agaagtagga atagacccaa
     4081 tattatgtgt tggagaaact ttagaacaaa gagaagctgg aaaaactaaa gatgtttgta
     4141 aagttcaagt tgaaaaagct ttagaaaatg ttcttaaaga tgatttatca aaagtagttg
     4201 ttgcatatga gccaatctgg gctattggaa ctggtaaaac tgcaactgct gaagatgcta
     4261 atgacgttat atcttatata agagaagtta taaaaggatt atatggagaa ttagctaatg
     4321 aagttagaat acaatacggt ggaagtgtta aaccttcaaa tgtagccgaa ataatgggtc
     4381 aaagtgatat agatggagct ttagtaggtg gagctagttt agctagtaat gattacctag
     4441 accttgttaa tttctaagga gtgaaatgat gaaaaaacca gttgctttaa ttattatgga
     4501 cgggtttgga tacaataagg atgttaaggg aaatgcaatt gctgagtcca aaactcctaa
     4561 tttagataga ataaaaaaag agtatccaaa cacattgata aatgctagtg gtcttgatgt
     4621 tggtctacct gatggtcaaa tgggaaattc agaagttgga cacactaaca taggtgcagg
     4681 tagaatagta tatcaagatt taactagaat aacaaaatct ataaaagatg gtgacttttt
     4741 tgctaataaa gttttatgtg aagcaatgga taatgcaaaa gaaaattctc ttcatgtaat
     4801 gggacttttg tctgatggag gagtacattc acatatagac catcttaagg ctataatcaa
     4861 aatggcaaaa gataaaggcg tacaaaaggt gtatgttcac gcatttactg atggtagaga
     4921 tactgaccct caaagtgcat tagaatatgc caaagaagta caagctagta tggatgaaat
     4981 tggagtaggt gaatttgcta cagtttctgg tagatactac gctatggata gagataagag
     5041 atgggaaaga gtagaacttg catacaatgc catggttaga ggtattggtg aaaaagcaaa
     5101 ttctattgag gaagctattc aaaactctta tgatgatgga aaaaatgatg agtttataat
     5161 gccaacagtt attatgaaag atgataaacc agttggaagt ataaaggaaa atgattcaat
     5221 tatattcttc aactttagac cagatagagc tagacaaata actagagctt tagtttgtga
     5281 agagtttgat ggatttaaaa gagaagatat taaaaacttc tttgtatgct taacagagta
     5341 cgatataact atagagaatg tgcatatagc atttggacct caatctttag ccaacacttt
     5401 aggtgagtat ctagctaaaa atggaaaaac tcaacttaga gctgctgaaa ctgaaaagta
     5461 tgcacatgta actttcttct tcaatggtgg agtagaagag ccaaataaag gtgaagaaag
     5521 actattgata ccttctccaa aggttgcaac ttatgattta aaaccagaaa tgtcagcata
     5581 tgaattgaca gataaagctt tagataaatt aggagaagat aagtttgact ttatagtatt
     5641 aaactttgca aatcctgata tggtaggtca cacaggaagt atagaagcgg ctataaaggc
     5701 tgttgaaact gtagatactt gtgtaggaaa attgatagat aaaatagtag agttaggtgg
     5761 aagtgcaata ataactgctg accacggaaa tgctgaatat atgttagacc cggaaacagg
     5821 aaaaactgta acggctcact ctattaatcc agtaccattt attgtagttg gtcaagaata
     5881 tgaaagtgca aaattattgg atggaggaag attatctgat atagcaccga ctgttttaga
     5941 tatgatgaag ttagaaaagc cagaagaaat gactggtcat tcacttattt caaaatagtc
     6001 gattctgata agtagagaat aatatataaa ctacaatata aatttaaaaa taatgcagtt
     6061 taggtttatt ttgtaaagtt tagactttat gacataagat ttagattttg taagttctgg
     6121 atattgtaag gtgtagatga aggtatattt tataaaattt acaagataga caatttataa
     6181 aataaaaaat tataatatag ataataatgt aa
//
LOCUS       DAMJWO010000136         6157 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.141, whole genome shotgun sequence.
ACCESSION   DAMJWO010000136 DAMJWO010000000
VERSION     DAMJWO010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6157
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.141"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            227..1039
                     /locus_tag="PC366_003488"
     CDS             227..1039
                     /locus_tag="PC366_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HDF2578971.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNGVTEISDDLDSILTNVVEKIK"
     gene            complement(1128..1319)
                     /locus_tag="PC366_003489"
     CDS             complement(1128..1319)
                     /locus_tag="PC366_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578972.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTQPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            1624..1830
                     /locus_tag="PC366_003490"
     CDS             1624..1830
                     /locus_tag="PC366_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2578973.1"
                     /translation="MFKKKSGYTFTNFLNKVRVEKNKKYLLKKDLSILDVTVLIGFNS
                     QNYYSIIFKKFNNLTPIEYKNIYN"
     gene            2139..3758
                     /locus_tag="PC366_003491"
     CDS             2139..3758
                     /locus_tag="PC366_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HDF2578974.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPVLGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLVLNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDERFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFRNSHMIRLNNGNCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
     gene            4132..4326
                     /locus_tag="PC366_003492"
     CDS             4132..4326
                     /locus_tag="PC366_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2578975.1"
                     /translation="MINYMVEIIYSEKISEVENMLKIENIQYEFTSRDGFIFFGFYEM
                     TDAYRFETLCSDEKIRFKRI"
     gene            complement(4886..5209)
                     /locus_tag="PC366_003493"
     CDS             complement(4886..5209)
                     /locus_tag="PC366_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578976.1"
                     /translation="MATEIFTVKITPLEAQKMIKENIDADLVFSDSYNLGDDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTEKTVIKATSTGSAIGVLKIDWGAGGNLLKRVKNIL
                     AEYII"
     gene            complement(5254..5508)
                     /locus_tag="PC366_003494"
     CDS             complement(5254..5508)
                     /locus_tag="PC366_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578977.1"
                     /translation="MENKDFKLTICIFAFVIGVVVLFCCIGLGEFSAEHIIQQNGGIM
                     DTDQYNIYLDQSISQYRNFGSILALLGGIGILFDKYIRKY"
     gene            complement(5772..6053)
                     /locus_tag="PC366_003495"
     CDS             complement(5772..6053)
                     /locus_tag="PC366_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578978.1"
                     /translation="MASKQTPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDVVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
BASE COUNT         2265 a          773 c          744 g         2375 t
ORIGIN      
        1 tttctatata tttatatgac taagttctat aactaaattg aaataatcac tttttcaaga
       61 atgttataat ttttttattg tattcttttt gctatagtct atgaataaat caatagaaaa
      121 tcttctaagt tgcttttaaa taatgacttt atggttcaat tgtactaaaa tagtatatgt
      181 aggttacaaa taatctaata aatattaaag tttggaggta atagatatgg cagattgtaa
      241 ttcatgtcca tcaaagggaa attgtaatag tcaatcaaat tgttctattg aaaataaccc
      301 taacaataaa tttggaaaaa taattggtgt tatgagtggg aagggtggag ttggaaaatc
      361 aactgtaact gctttacttg ctaataagct aaacaaaatg ggatataagg ttggtatatt
      421 agattcagat ataactggac caagtattcc tagacttatg ggtgtaaaaa atgtaaaagc
      481 ttattctgat ggctcttata tttaccctgt agaaaactca aataacataa aagtaatgtc
      541 tataaacctt atgatagatg atgagaatga acctgttgtt tggagaggac ctttacttgg
      601 aggagttgta aagcaatttt atactgatgt actttgggaa gaattagact atttattaat
      661 agatatgcct cctggtactg gagatgttgc cttaacggtt atgcaatcta ttcctataag
      721 tggaatagtt atggtttcag tacctcaaga tttggtatct atgattgtat caaaagctgt
      781 taatatggct aaaaaaatga acataaatgt ccttggagtt attgaaaata tgagttatat
      841 ccaatgtcct gattgttcta aaaaaatcaa gttatttgaa ggagaatcta ctgaaaagtt
      901 tttagatgat ttagacttag agcttttagg agaacttcct atgactaaag aaattataga
      961 tattactcat aatggagtta cagaaattag tgatgattta gattcaatat tgactaatgt
     1021 tgttgaaaaa attaaataaa taaaaatttt ataattttat atttatcaaa aaaagaggct
     1081 tgtatttatt ttataatcat acaaataaat ataaacctct tttatgttta tctatgtttt
     1141 aaatacacaa aatattcttc tacttcatct ccatttttta cttttactaa gtattcatta
     1201 taatgagcat tatatggctg tgtcattttg cattctatta cattttctat gtcttctaat
     1261 tctaaaagtt ctacatcctt taaaaatttt ctttctatga gttccattaa tctttccata
     1321 atatatcctc acttccccta taattaagat aaactatata tcctcttaat acagagttta
     1381 tctgtttatt atattatatc caatatatta cagtttctaa catcattcat aaattatttt
     1441 aacaaataga gattgatttt ttaataaata tgccttgata aaatgaaaca tagaccaact
     1501 cttagtttta tgtaaagaaa acttaaagaa aactatagat tatattcaca aaaactactc
     1561 agaagatata acagtaagta atatatgtaa tgaattacaa cttaataaaa gttatttttt
     1621 tctttgttta agaaaaaaag tggatatact tttactaatt ttttaaataa agttagagtt
     1681 gaaaaaaaca aaaagtatct attaaaaaaa gacttgtcta ttttagacgt tactgtacta
     1741 attggattca atagtcaaaa ttactatagt ataattttta aaaagtttaa taaccttaca
     1801 ccaattgaat ataaaaatat ttataactaa aaaatatcat tctaaaagga tgctattttt
     1861 ttacatattt tttacaatta tagttaattc tttgttaaat tgattgtaca taaaatacta
     1921 aaaatctaag ttcaagtatt taaattgcta tatatcataa attttctaaa attaacaaca
     1981 acttaaaaat ttaacattct cttaacgtat acttaacaaa acattaatat ttctattgac
     2041 aaaatttgtt attctatatt atggaaacaa taaattttag ttaataaagt ttataattca
     2101 gataaaaaaa ctattaattt cttaagggag gaaatatcgt gaatatagta attagcctta
     2161 tcggtggact tggacttttt ctttacggaa tgagtttaat gggagaaggt ttacaaaaat
     2221 cagcaggaga caaattaaaa aaaattattg aactcttaac aagtaatgtt gttatgggtg
     2281 tactggtagg tacagtcgtt acaggtatta tacaaagttc aagtgctact actgttatgg
     2341 ttgtaggatt tgtaaatgca ggtataatga atctaagtca agctattggt gtaataatgg
     2401 gggcaaatat aggtactaca gttactgctc aattagtttc atttaatctt gaaggaattg
     2461 caccaattgc tttaggtata ggtattttat tctatttatt tacatcaaat caaaaaacaa
     2521 agcatttatc tgagatactt ataggttttg gtatattatt tacaggaatg gagtttatga
     2581 aagatgcagt agctccactt gctgaatata aagcattcac tgatgcactt ttatatttta
     2641 gtaaaaatcc tgtattaggt atattggcag gatttgccat aactggtatt gttcaaagtt
     2701 caagtgcatc tatgggtatg ttaatagcac tagcttctca aggaatactt cctctatcat
     2761 ctgctttacc tattctttat ggagataata taggtacttg tgttacttca cttttatcaa
     2821 gtgttggtgc aagtagaaat gctcgacgtg cagctgtaat gcatttaagt tttaatgtca
     2881 ttggtacaat aatatttatg cttgttttaa ataaacctat atcagccata gttactcatt
     2941 ttgacccaac tgatacagct agacaaatag caaatgcaca tactttattt aatcttacaa
     3001 atgttataat attattacca ttttctaaat acatagttaa attagcaaat agacttatac
     3061 ctattaaaga aactgaatca gaaatagtaa ataatactaa gtacttagat gaaaggatgt
     3121 ttagcactcc atctatagca cttggtaata ctgtacaaga agttgtaaga atgggtcata
     3181 aagctacaaa ctctttggaa cattcaattg caggattttt aaataagagc aatgaagata
     3241 ttaataaagc ttttgagtca gaaaaagttg tcaataagtt acagaaagat atattgaact
     3301 atttgttaaa actttctaaa gaacctctta gagacgatga acgctttaga acagatttgc
     3361 tttttaatac tgtaaatgac attgaaagag tctctgacca tgcagaaaat atagctgaat
     3421 tggccatgag tgttaaggaa atgaacatta gtttttctga tagtgcgata agagaaatat
     3481 acgaaatata caataagaca attactaatt ttaaggatgc cttaatagtt ttagatgtta
     3541 aagattttga gttagcaaat aaagttttag aagttgaaaa tgaagtaaat tatttagaaa
     3601 aaacttttag aaattcacat atgattagac taaataatgg aaattgtaca attgatgctg
     3661 gtgtacttta tcttgactta cttactaatc tagaaagaat ttctgaccac tcaacaaata
     3721 tagtaaaaca agtattaaaa cttaaacaaa aaatatagtg attattttta tatataatct
     3781 taatcaatga gaagtaagaa gctatagata atgcttatat catttatggc ttcttatttt
     3841 ttatgtaata ctcaaatttt tatagtattc tcttattatt aaacagcttc tgcctagaat
     3901 attccatata tatatgactt ctttcataaa acttgaactg cccataacta aagtcacaag
     3961 tatacataac tattttttaa tcaattataa ccaatattta ttttatttat cttcatttta
     4021 attcttcatt caataatgta ataagattat tttttatttg gatactatta tatcatctaa
     4081 atatgttatt atatatttgg atattttcat attaatagga gggattctac aatgataaat
     4141 tatatggtag aaattatata tagcgaaaaa ataagcgaag tagaaaacat gttgaaaatt
     4201 gaaaatatac aatatgaatt tacttctcgt gatggcttta tattttttgg tttttatgag
     4261 atgacagatg catatagatt tgagacttta tgttcagatg aaaaaattcg atttaaaaga
     4321 atataataaa taaaaaaagt acatatttct aaactatttg tttttcaaat ttaggttgtg
     4381 ttttaatgta gtgttgatat cataaacaat tttaataata aaaaagtagg aatattatat
     4441 taatatgctc ctacttttta ctcatattta ttaatattat ttatcaaaac taccctacaa
     4501 actggaattt atcattcttt cataatttta aactatcata tttaaaatat ataaaattct
     4561 acttgatttt tgtataaacg taatatcaat cattatccaa tttaaaagta ttttttagta
     4621 atttccattt cattttcttt taacatatta attaaacttt tatatgtaaa tggtgtattt
     4681 acatattatt taatatccaa caattatata aagaaatgta ctctttgcct tataaagaat
     4741 tataaagcca attcgtttta ttatattatt tttctttata cattaaaaac tttaccttca
     4801 aatccttatt tatctatata ttataaaaat attcttaacc tcttttacga gattttcttg
     4861 acatattatc agttagataa aataattaaa taatatattc agcaagtatg ttttttactc
     4921 ttttaagtaa atttccacct gcaccccaat caatttttaa aactccaatt gcactgcctg
     4981 ttgaagtagc tttaataact gttttttctg tggtattttc ataaactacg attaatcctg
     5041 catcactatt atttcttgcg taatacttct caaaagttgt aattagtata aatttatcat
     5101 ctcctaaatt ataagaatca ctaaaaacta aatctgcatc aatattttct tttatcattt
     5161 tttgtgcttc taagggtgta atttttacag taaatatttc tgttgccatt ttttatctcc
     5221 tcataagaat ttattttaga caaaacataa tctctagtat tttctgatat atttatcaaa
     5281 caatatccct attcctccta acagagctaa tatagaacca aaatttctat attgagaaat
     5341 agattggtct agataaatat tatattggtc agtatccatg attccaccat tttgttgaat
     5401 aatatgctct gcactaaatt cacccaaacc tatacagcag aataatacta ctactccaat
     5461 tacaaaagca aatatacata ttgttaattt aaaatcctta ttttccatag ttatccctct
     5521 cataagttaa atttatttga ttatttttac tagattttat attactctta ttatacaata
     5581 gaacatatat ttacatctat ttccaaaatt gtaaccttta tagttttata tatttaaatt
     5641 ttttaaacaa aaaatacaca tctataaatt ataaatgtgt attctgcacc attactaata
     5701 atatattata cttttttaca aatttctaat tatttataac tattcaaaaa taaaattcat
     5761 ataaaataat tctattgtac aattgaaact ttaataatat ctccattttt tctctccaag
     5821 tgaactactt ctccagttaa atcatagtca aatgctttga ctaatatttc agtaaccttt
     5881 ttaccatcta ctacatcatc ttttccatta aataaatcca aagcattatt ctcaatcatt
     5941 ctttttgcaa aatttacagg taactttata tgtattttat cgcctgtatg tgataagact
     6001 cttattctta aaaacttttc taaattgttt cttggtgttt gttttgatgc catacgatta
     6061 aatcactctc ctttattttt tatttaataa taaattttat tcttaaaaat atctttatat
     6121 gtatttatta tgaaagtaac actattattt tctaatc
//
LOCUS       DAMJWO010000137         6027 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.142, whole genome shotgun sequence.
ACCESSION   DAMJWO010000137 DAMJWO010000000
VERSION     DAMJWO010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6027
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.142"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(214..723)
                     /locus_tag="PC366_003496"
     CDS             complement(214..723)
                     /locus_tag="PC366_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HDF2578979.1"
                     /translation="MSQQNTGNAIVNSKPKKTAVEIFMGGAKKGFYIGVEQILPAMIM
                     GYVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVVVLIAAFFAKAAGAATAANLFAQ
                     GLITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVR
                     VLLTVMGLM"
     gene            complement(725..1372)
                     /locus_tag="PC366_003497"
     CDS             complement(725..1372)
                     /locus_tag="PC366_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578980.1"
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANL
                     TGSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIF
                     NPLLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSA
                     VILNTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            complement(1386..2558)
                     /locus_tag="PC366_003498"
     CDS             complement(1386..2558)
                     /locus_tag="PC366_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2578981.1"
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNIESYTHCKESVNKLAE
                     RLKLEFEKEGLDCELVDVGENGNTLIGTLGSNIDKKPIIFSGHMDTVFETGTFGENPF
                     KIIEGKAYGPGVLDMKGGIIISLYVIKALNKIGYKERPIKIVFSGDEEIGHKDSTGAD
                     VILREAKGALCAFNMETGLVDNSLCIGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEE
                     MANKILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQ
                     VREICKETYIEGTSTEVNFISEMMPFETTEDVMRFHTFVNEVSRENGFGELNAKRLGG
                     SSDASYLTIANVPTICSFGVRGEWNHTSREYAVVDSMFERVKLISTVILNLDKFEV"
     gene            2826..4202
                     /locus_tag="PC366_003499"
     CDS             2826..4202
                     /locus_tag="PC366_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578982.1"
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNN
                     LPNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDERDFYKYLFKLLNSQ
                     KDIDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIH
                     LDLLRDNKINLSFTRNYIISCELNKLGYDCIYMVPSTESILNTFKSLVNEITLQNLDK
                     NKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEI
                     HTTKEILNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLN
                     GNCTFIVNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNS
                     NNVSAEILADYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFL
                     NKMQKLNS"
     gene            complement(4453..5286)
                     /locus_tag="PC366_003500"
     CDS             complement(4453..5286)
                     /locus_tag="PC366_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDF2578983.1"
                     /translation="MTIKEVEEKTGLTRSNIRFYENENLIKPLRNERNGYREYSDENV
                     EDIKKIAYLRTLGITIDDIRNIILQKVSLVEVVEKQEKVLETKISDLENAKTMCNKML
                     ESDELSYLNLKVEQYITELPEYWNKNKPVFKLDSVSFLYIWGGKITWGIITIACLLIA
                     ITVFPKLPPQIPIQWNNGVANYVDKKFIYAYPVICVVFRILLRPFIWRWLQIHAFYSD
                     TIADYLTNFMCFVALSIEIFSILFIYNIARHVTIIIFIDILVFIVLLIIGVYKLFKKY
                     N"
     gene            complement(5615..>6027)
                     /locus_tag="PC366_003501"
     CDS             complement(5615..>6027)
                     /locus_tag="PC366_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDF2578984.1"
                     /translation="GIDYENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMG
                     ASKKGSYGASIIEKIESIIPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHIRQ
                     QLNNHEESQSHPDEQEIYEASMFAKNMMIKASIV"
BASE COUNT         2102 a         1028 c          646 g         2251 t
ORIGIN      
        1 tttcattgtt gaaattatga aaatatactt gatttaatac caaaagagta tctcatgaac
       61 taaaaagttc attttgagat actctcttct tttttaatta atatacatat taattactat
      121 attagtttat tactatatat caattactat tcattaatta ctattcatca attcttatat
      181 atcatttata attaggttat aattttatgt tatttacatt aatcccataa cagtgagtaa
      241 aactcttact atcaacatcc ccactattgc atcaaatata ggaactgcca acagtaacat
      301 tctatactta gtactggcat ttgctacaag cactattctg gcataatgac caactagagt
      361 acccattaac atacatggca taattaatat ggttgcttgt ggtgcagtga ttagaccttg
      421 tgcaaataag tttgcagctg tagctgctcc tgctgcctta gcaaagaatg ctgctatcaa
      481 aactacaaca gattccccag gtagtccaaa aatacccatt actggaccaa aaatatttcc
      541 taaaatatca actaaaccag ttaattgtaa aaactgcact attacataac ccattatcat
      601 ggctggtaat atctgttcaa cacctatgta aaaacctttt tttgctcccc ccataaatat
      661 ctcaacagca gttttcttag gtttactatt tacaattgca tttccagtat tttgttgact
      721 catactacac agcctcctta gccttattct ttttatttct tacacctatg attaatctaa
      781 ctagattagc accaagtatt ttacagaata tctctataag gattattgga cctaatgcca
      841 ataatgctat tggtaaaagt ggagcttgag tatttattgt gttcagtata acagctgaac
      901 cagcatattg atatgctaca aatatagttc tttcatcatc tgttatttcc ccactttcaa
      961 ataattcttt cgtcattatt gaggctacat ctgaactagt aaatgaagat acaaatgcta
     1021 ttcctgctat tccaggtata ccaagcagag gtctaagtaa tggattaaat atctttgatg
     1081 ctgctttcat tcctcccata gattcaacta catctataag acctacagca aaacagacag
     1141 ttggaatcaa agtcagagca aataagaaac catcttttgc tcccgttcct cctttaccca
     1201 taaagtctac accatctgca atagtaccaa atgaacctgt cagattagca aaatctaatg
     1261 ctttaaggaa gccttgacta tctttaaata ctcctgaaaa taatactatc aatacaaata
     1321 aagataaata ccctttccat gttaccttat tatctccagc tgttacatcc atataaaatc
     1381 cccctttata cctcaaattt atctaagttt aaaataactg tagaaattaa tttcaccctc
     1441 tcaaacatag aatctactac tgcatattct cttgatgtgt ggttccattc tcctcttaca
     1501 ccaaatgaac agattgtagg aacgtttgca atagttaaat aacttgcatc tgaactacct
     1561 ccaagtctct tagcatttaa ttctccaaat ccattttctc ttgacacttc atttacaaat
     1621 gtatgaaatc tcataacatc ttctgtagtt tcaaatggca tcatttcact tataaaatta
     1681 acttctgtag aagttccttc tatgtaagtt tctttacata tctctctaac ttgttcttta
     1741 acattctcca tttcttctac tttttcaaat ctaaggtcta cttttatact acaatcttct
     1801 ggaatagaat tttccactct tccaccctta atcacactta cacttactgt agttccaaca
     1861 tctaaattag tcaatttttg tatgcgtagt atcttattag ccatttcttc tatagcattt
     1921 cttccacctt caaaatcatt acctgcatgt gtttctacac cttttacatg tatattacat
     1981 cctattcttc cttttctacc tatacataaa ctattatcta ctaatccagt ttccatatta
     2041 aaagcacaaa gagcaccttt tgcttccctc aatataacat ctgcaccagt tgaatcttta
     2101 tgacctatct cttcatctcc agaaaatact atttttattg gtctttcttt gtatcctatt
     2161 ttatttaaag ctttaataac gtataaagag attattatac cccccttcat atctaaaaca
     2221 cctgggccat atgcttttcc ttctattatt ttaaatggat tctctccaaa tgtacctgtt
     2281 tcaaagacag tatccatgtg tcctgaaaaa attatcggct ttttatctat attagaacca
     2341 agtgtaccta tcaatgtatt accattttcc ccaacatcta ctagttcaca atccaaacct
     2401 tctttttcaa attcaagctt taatctctca gctaacttgt ttacactttc tttacaatgt
     2461 gtataacttt ctatattaac aatctctttc cataatgaaa ctatttcttc tctattctca
     2521 tcaacaaact tagaaatttc atttaaatat gtattcataa tcttctcctt tattttcaaa
     2581 taaaatgtat ttctttccta aaatctaagt ttattttagg aaatcttaaa agactagtcc
     2641 ttaattacaa aatagcacaa ttattcttgc cagtcaacat atttttcagt cttttttata
     2701 ttttctgatt tttctttcaa ttatcctttt gtaaaataaa ttgacgcgtt ttatctacta
     2761 ttataaaatg aggttataaa ttgattgatt agttacaata ctctcgaaat tttaaaggag
     2821 gttttatgaa atataaaatt ggttttttga caacatctta ttttatgtca gataagttta
     2881 aacaagctct taaagaatta aatgatactt gtgaaattac atttattgag cttaaagggg
     2941 agaatccttt taataattta cctaatatat actatgagca agtagataat tttgatggat
     3001 ttgtatgcag tggtatagtt ccatatagtg aacttataat aaatataaaa gacataaaag
     3061 ttccattaaa ttttttaaag cttgatgaaa gagattttta taaatactta ttcaaattat
     3121 taaatagcca aaaagatatt gactttacaa aatcatttat ggatttttta agagaggaca
     3181 acaattatta tgatatatat tcattaatag actctaataa atgtccatat acaattaaag
     3241 attttaatat ccctcaacct gtatatgact ttaaaaaatt aaatgataaa ttattggaaa
     3301 tacatttaga cttattgcga gataataaga ttaacctttc ttttactaga aattacatca
     3361 ttagttgtga acttaataag cttggatatg attgtattta catggttcca tctacagaat
     3421 caatcctgaa tacatttaaa tctctggtga atgaaataac attacaaaac ttagacaaaa
     3481 ataaatctgc aacttgtata gttacagtaa atagttcaga gtacataaat gaagatttga
     3541 tatttaaaaa tgatgagata caaaatcaaa tatataacac tatattaaat tctctatcaa
     3601 gacatggatt ctatggagtt caggtcaaaa aaaatgatat gaaaatagag atacacacta
     3661 ctaaagaaat attaaacaat atgaccaata actatacaga tttttttatt tcagaagatt
     3721 taaaagaaat taaatatagc ttaaatatag gttggggcat tggaaataca aatattcatg
     3781 cagagcaaaa tgctcgtcag gctaatggta aatctgcttc tttgaatgga aactgtactt
     3841 ttatagtaaa tgatactaat gatacaatag gccctttata ttcaaataaa aattctaata
     3901 atattgaaga tagctcaata gccaataaag ttgcttcttt tatacctcta tctaatacaa
     3961 atgtatctaa aatcatgtgt atgattaatg atagaaattc aaataatgtg tcagcagaaa
     4021 tattagcaga ctatatgaac ataactctta gaagtgctaa tagaatattg agtatcttat
     4081 ataaagcagg aattgcaact attgtaaata caaaactcga taatcaaaga ggaaggccaa
     4141 aaaaaatata taaagttgat ttcttatctt ttctaaataa gatgcagaaa ttaaattctt
     4201 aatatttaat tttttaataa aagcaatgta ttttctctaa ttttaaagaa tcaaaatgtt
     4261 taaattttat tagaatatac aactttttac tttaaaatac ctaaaccttt tatcagtgaa
     4321 ataaaccata atatatcgta gcttattaga aaaacaaaat aatttcatat acaaataata
     4381 aaatagccac tacaatccat aatttgcagt ggctactttt tacactatca cttattactt
     4441 aatttttaaa aattaattgt attttttaaa taatttatac acacctatta tcagtaaaac
     4501 aataaataca agtatatcta taaaaataat tattgtaaca tgtctggcaa tattgtaaat
     4561 aaaaagtata gagaatattt ctatagacaa cgctacaaaa cacataaaat tcgttaaata
     4621 atctgcaata gtatcactat aaaaagcatg tatttgtaac catctccata taaatggacg
     4681 taaaaggatt ctgaatacaa cacaaatgac agggtaggca taaataaatt ttttatctac
     4741 ataattagct acaccattat tccattggat aggaatttga ggtggcaact ttggaaatac
     4801 tgttattgca atcaacaaac aagcaatagt aataattccc caggtaattt tccctcccca
     4861 tatatataag aaacttacag agtcaagttt aaaaacaggt ttgtttttat tccagtattc
     4921 tggcaactca gttatgtatt gctctacttt caaattcaaa taacttagct catcagattc
     4981 taacatttta ttacacatag tttttgcatt ttctaagtct gatattttag tttcgagaac
     5041 tttctcctgt ttctctacaa cttcaactaa agatactttc tgtaatataa tattacggat
     5101 atcatcaata gtaattccta gtgtacgtaa atatgcaatt tttttgatgt cctctacatt
     5161 ttcatctgaa tattctctat agccattacg ctcattacga aggggtttaa ttaaattctc
     5221 gttctcataa aaacgaatat tagagcgtgt caatcctgtt ttttcttcaa cttctttaat
     5281 tgtcatttta aacactacct ctctattcta ttaatttaca actataatat agtcttaaat
     5341 attttcactc tataaaattg tatatttagt atatcttaaa atcaagttaa ttatctttta
     5401 taaattttca tacaataata tctcctttca ataatatctc tttttctata tttaaaacta
     5461 tcttattttc tataaaataa tgtataaaca aggtttacag tcaagtattt ttattatttt
     5521 tttgatttca taaaaaaaag catagcaaat catttgctat acttttttac taaattattt
     5581 attctatatc ttatatgaac ttattgttta actactacac aatactagct ttaatcatca
     5641 tattttttgc aaacatactg gcttcatata tttcttgttc atctggatga ctttgagatt
     5701 cctcatggtt atttaattgt tggcgaatat gttcgttgtc aggagaaagt tttaacatct
     5761 ctttatattt tgctttcaat ccttctgcta tcttaccttg acatatgaat gaacctaata
     5821 tttcattatc ttttgggata attgattcta tcttttctat tatactagct ccataacttc
     5881 cttttttact tgctcccatt gttccaaata gtgctatctt tttattgtga atattttcaa
     5941 gcacttgttt tgaattttta tcacaaattc ccttgtccac ccaatagcct aagaatacta
     6001 tatcataatt ttcatagtca ataccat
//
LOCUS       DAMJWO010000138         6012 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.143, whole genome shotgun sequence.
ACCESSION   DAMJWO010000138 DAMJWO010000000
VERSION     DAMJWO010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6012
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.143"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            142..429
                     /locus_tag="PC366_003502"
     CDS             142..429
                     /locus_tag="PC366_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578985.1"
                     /translation="MKKILYALYSFIVIIANFRLKEKNYNFILLAIFFILLLIQNGVL
                     KTGYQNRATFYQDNYFNGEDKNDKIKFITIKIFIFLSLPLCFNILFNYLTS"
     gene            complement(967..1518)
                     /locus_tag="PC366_003503"
     CDS             complement(967..1518)
                     /locus_tag="PC366_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2578986.1"
                     /translation="MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SIHTYHNQGEKTLKAVIINYYPV"
     gene            1709..2671
                     /locus_tag="PC366_003504"
     CDS             1709..2671
                     /locus_tag="PC366_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HDF2578987.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLEA
                     CNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETA
                     AIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSSEKGKNIVLTLNDSGLKYLSTDLYEEL"
     gene            2966..4810
                     /locus_tag="PC366_003505"
     CDS             2966..4810
                     /locus_tag="PC366_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDF2578988.1"
                     /translation="MQKRILRNFIFTGKNILSKLVFIIKYNFSTLILFELFHKGLALF
                     FIWPSIRYIFDILIKSLHIVYLNMDNFIKVLTNPMSIVLIILSVIILAFYAFFEFTSV
                     IICFNKSIKYEKIGLFELFKISFKNSIKLLYPKNILLFIFVILIIPLVNTVLISGFIG
                     KIQIPEYILDYIKSDIILNIIYMIFLLIIYISVIRWIFSIHEITLNTENFKRARKESV
                     NLIKRKIIRTIIYSLILSLVVAIIGYAIYHSGIIFIGIWTKYCTDMEFLKNVFINRCI
                     AFEEYFRLILSIFIFILDIGFISATYYQYKGVNISKNNIKKEKKSISKIVFNLVLILL
                     ISYIESVAFSSHINGMFNTSFSFYTTAIAHRAGAEMAPENTLAAIEEASNAKADYAEI
                     DVQETKDGELIVLHDSNFKRTTGVDKNVWDVNYNEVKTYDAGSFYYYGKGYYDEKFVG
                     EKIPTLKEMIKYSKGKVKLLIEIKLNGHEKGDIVKKVVQLIKENNFENQCIVASMDKT
                     ILQKVKKLDENLLTCYFMAIAYGDFSKLNYVDIYGIESTFVNKTVVEKIHKMNKKIFV
                     WTVNSDSLIEKMLDLNVDSIITDNPYLIESAIYWKKNGFISQVSDYLF"
     gene            5132..5716
                     /locus_tag="PC366_003506"
     CDS             5132..5716
                     /locus_tag="PC366_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDF2578989.1"
                     /translation="MTEREKMLAGELYDCGDIELLTQWHKAKDLVRDYNQTDSSDLEK
                     KEKILNELLGGKDKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALI
                     APNVQIYTAFHPTNAGDRFGNVKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTI
                     GDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK"
BASE COUNT         2357 a          594 c          920 g         2141 t
ORIGIN      
        1 atataaagag atgtccttta aaaataaaaa ttaaaaaata tttaatgcta ctacaatagg
       61 aactagaact gcacttaata aatatacaga aattagattt ggctcaatat aaaatacaaa
      121 tatagaattt aggtgttttt tatgaaaaaa attttatatg ctttatatag tttcattgtt
      181 attatagcta attttagatt aaaagaaaaa aattataact ttattttatt agcaatcttt
      241 tttatactgc tgttaattca aaatggagtt ttaaaaacag gttatcaaaa tagagctaca
      301 ttttatcaag ataattattt taatggagag gataaaaatg ataagataaa atttataact
      361 ataaagattt ttatattttt gtcattacca ttatgtttta atatactatt caattattta
      421 acttcttaaa ttatatttag atataggagt gttatgataa aagtaagatt atgtgttgtt
      481 tatattaaat ataaagtgca tatagtgata aaacaaaagt ttcatataaa tgaagaaaaa
      541 atataaaata atttatttaa ctacttaaaa ataaactaaa agggataata aaatagcttt
      601 taggttatgg taataaaggt atttaaaaag agtgcataag cactccaatt gtgagaaata
      661 catacacaaa tcattattac aacaatgaaa aatgtacata taagagacgt tttgtatttg
      721 ttttaagtga taatatttta atactaacta aataattatc acaataataa aaaagaaaaa
      781 ggagtatttt gtactccatt tgtcaaaaat ataaaacttt tatataagct tattataaca
      841 taattgataa aagtgtaaag ctatataatg aatttataaa gaaaaataaa ataaaaaaga
      901 taaatcctaa tcaaaggatt tatctttttg tatagaaaat aattattcta ttattaaatg
      961 gcatggctaa actggataat aatttattat tactgctttc aatgtttttt ctccttgatt
     1021 atggtatgta tgaattgatt cagctgaaaa acaaatagag tcattttctc taagttgata
     1081 aatagagtca tttacttcta attttaattg accttctata atcataatat attcctgtga
     1141 tttttcagaa tgaccaacag atgtataact atgaccttct tctaattcca tttgaaataa
     1201 ttcgaagttt ctagttggtg tattgggata ataacaataa agacgataat ctttattttc
     1261 tgaaacttgt acatctatat cagtttttga tacaataaaa gtttcatttt gaggttgttc
     1321 cagtattgca gtatatggaa catttagtcc acttgcaatt ttccaaattg tgtttactgt
     1381 tgggtttgag tctccctttt caatttgcga aagcattact ttacttacgc cagataattc
     1441 agcaagttga cctagactta agttacgttc attacgtaat ctatttaaat ttttagcaat
     1501 aacagtatta atactcatag taactcctta aaatgtaaat tattgacaaa tataatttac
     1561 gaatgtataa tttatttaac attatttata atttacaaat gtataatata atgaacgtta
     1621 aatacactgt acatccgtaa tataaattat actgcataaa gagttgtttt tcaacggatg
     1681 atagttgaga gattaagggg gaattgtaat gcgtgtactt aataatgtta cagaggctat
     1741 aggcaatact catatgttac atttatccaa aatagcagat gaatttggag ttcaaggtaa
     1801 tatttatgca aagatggaat acttaaatcc gggatttagt aaaaaggacc gtgtagcatt
     1861 acaaatgatt accgaagcag aaaatgcagg tttattagtt ccaggtcaag cagttgtgga
     1921 attaacaagt ggtaatactg gaacaggact agcaatagct tgtgcatgta aaggatataa
     1981 atttatagcg tgtatgtcaa aaggaaattc tatggaaaga gcaagaatga tgaaagcttt
     2041 aggtgctgaa gtagttcttg tagaccaaat gcctaattca gttcacggac aggtatctgg
     2101 tgaagatttg gcacttgtag aaattgaggc tcaaaaaata gcaaaagaaa gaaatgcatt
     2161 tagagcagac caatttaatt tagaagcttg taatcatgca catgaaaagt atacagcaga
     2221 agaaatgtgg gaacaattgg atggaaatat tgatgtattt gtagattttc ttggaagtgg
     2281 tagtactttt gcaggatgtt caaaaacact taaaaaacat aattcttcta tcaaatgtta
     2341 tgttgttgaa cctgaaacag cagcaattta ttcaggtaaa gaaataactg accaagggca
     2401 taaaatacaa ggtggaggat attctatgga tttgccatta gtagacaaga aacttattga
     2461 tggttatatt caagttacag acgaggaggc aactgatgta gcaagaaaat tagctaaatt
     2521 agaaggtgta tttgcaggat tttcttcagg ggcaaatgtg tgtgcagcaa ttaagttgtt
     2581 aaagagcagt gaaaaaggaa aaaatatagt tttaactctt aatgatagtg gtttaaaata
     2641 tttaagtact gatttatatg aagaattgta ataatagcac aatagttatg caatgttttt
     2701 taaattaagt atatagattt aaattataaa aagtatctca atgtgatttt tgaaagttat
     2761 aaaagagata cttttttatt ttgtaaatat ggagtatcct acttataagt attaagctat
     2821 atagatattg atgattagct atgcaataaa aaagagtatg tgtttttgca tttatacatc
     2881 ataacttgga ataatacata ttaatgttct aaatgtattt aaaacatatg ataaaattag
     2941 aacaaacaga tacaaggaga taaacatgca aaagagaatt ttaagaaatt ttatatttac
     3001 gggtaaaaat attttaagta aacttgtttt tataataaaa tataatttta gtacattaat
     3061 tttatttgaa ttatttcata aaggattagc cttatttttt atatggccat ctattagata
     3121 tatatttgat attttaataa aaagtttaca tatagtctac ctaaatatgg ataattttat
     3181 aaaagttttg accaatccca tgtcaatagt tctgataata ctatcagtta taatactagc
     3241 tttttatgca ttttttgaat ttacctctgt aattatttgt tttaataaat cgataaaata
     3301 tgaaaaaata gggttatttg aactctttaa aatatcattt aagaactcta taaaattgtt
     3361 atatcctaaa aatatactat tatttatatt tgtgatatta ataattccat tagtaaatac
     3421 agttttaatt tcagggttta taggaaaaat acaaatacca gagtacatat tagattatat
     3481 aaagtctgat ataattttaa atataatcta tatgattttt cttttaataa tctatatttc
     3541 ggttattaga tggattttta gcattcatga gataacttta aatacagaaa attttaaaag
     3601 agcaagaaaa gaaagtgtta atcttataaa gagaaagatt ataagaacaa ttatttattc
     3661 attaatatta tctttagtag tagctattat tggatatgcg atttatcata gtggaattat
     3721 atttataggc atatggacta aatattgtac tgatatggaa tttttgaaga atgtatttat
     3781 aaatagatgt attgcatttg aagaatattt tagattgatt ttatcaatat tcatttttat
     3841 attggacatt ggatttatct cagcaactta ttatcaatat aaaggagtaa atatttctaa
     3901 aaataatatt aaaaaagaga aaaaatctat atcaaaaatt gtttttaatt tagtattaat
     3961 attattgatt tcttatatag agtcagttgc attttcttca catataaatg gcatgtttaa
     4021 tacgtcattt tcattttata caacagcaat tgctcataga gcaggagctg aaatggctcc
     4081 agagaatact ttggcagcaa tagaagaagc ttcaaatgct aaagctgatt atgcagaaat
     4141 agatgttcaa gaaactaaag atggagaact tattgtactt catgattcaa actttaagag
     4201 aactacagga gtagataaaa atgtttggga tgtaaattat aatgaagtaa agacatatga
     4261 tgcgggaagc ttttattatt atggaaaagg ttattatgat gaaaagtttg ttggggaaaa
     4321 gataccaaca ctcaaagaaa tgataaaata ttctaaaggt aaggtgaaat tattaataga
     4381 aataaaactt aatggacatg aaaagggaga catagtaaaa aaagttgttc agttaattaa
     4441 agaaaataat tttgaaaatc aatgtatagt tgcatctatg gataaaacta tattacaaaa
     4501 agtaaaaaaa ctggatgaga atttactgac atgctatttt atggcaattg catatggtga
     4561 tttttcaaag ttaaattatg ttgatatata tggaattgaa tcaacttttg ttaataaaac
     4621 agtagtagaa aagattcata aaatgaacaa aaaaatcttc gtttggactg ttaatagtga
     4681 cagtttaatt gagaaaatgc ttgacctaaa tgtagatagt attattacag ataatccata
     4741 ccttatagag agtgcaattt attggaagaa aaatggattt attagtcaag tgtcagatta
     4801 tttattttaa atattctata attgtattat ccagtaaaag agatattatt aaaatcaata
     4861 atatctcttt ttaacataaa taaggttgtt aaattaaggt tattcttata aaaattgtgc
     4921 ttatcagcta taaacaagga ataaaagtga aaaaattgct ctgagattat tacagttaaa
     4981 agagttttaa gatgacagag agatagattg tcaactgtat atttaataaa tcttgttatt
     5041 tattaaattt tatataagta aaatatataa attaataaat cttatgctag aatatatatg
     5101 aaaaacaata taaatttgga ggattaaaaa catgacagag cgagaaaaaa tgttggcagg
     5161 agaactttac gattgtggtg atattgagtt gttaactcaa tggcataaag caaaagacct
     5221 agtaagagat tataaccaaa cagattcctc ggatttggaa aaaaaagaaa aaatattaaa
     5281 tgaattactt ggtggtaagg ataaaaactt atggattact gcaccgtatt atgtagatta
     5341 tggaaataat atttattttg gaaataattg tgaagtcaat atgaattgta cgtttttaga
     5401 tgataataaa attatcattg gggataatgc actaatcgca ccaaacgtac aaatatatac
     5461 tgcatttcat ccaactaatg ctggtgatag atttggtaat gtcaaagaag atggttcatt
     5521 tgaattttgt aaaactcaaa cagctccagt tactattgga gataatgttt ggattggcgg
     5581 gggtgctatt atcatgccag gtgttactat tggagataat gtagttatag gtgcaggaag
     5641 tattgttaca aaagatattc caagtaatat gattgcatac ggaaatccat gccgtattat
     5701 tcgagaaaac aaataaagtt aaattttctt gcaaaatctc aaaaaacacc tttcttactt
     5761 tatacatagg gtattttcca atactttcac atccatattc atttgttaaa tttttgtgga
     5821 atgtagtttt tatcacttct atcttacatt tccaccattt tttataaaag tcattccttt
     5881 atagatttat ttataatagt atatattcta tttgatgttt gaataagcac ttatttttaa
     5941 gtaaaatact aacttttagg ttagtatttt gctatagtat gatgattaag taagaataaa
     6001 atactataat ac
//
LOCUS       DAMJWO010000139         5982 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.144, whole genome shotgun sequence.
ACCESSION   DAMJWO010000139 DAMJWO010000000
VERSION     DAMJWO010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5982
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.144"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..560
                     /locus_tag="PC366_003507"
     CDS             <1..560
                     /locus_tag="PC366_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2578990.1"
                     /translation="ITSLYIFKNFKIGILLVFYFLFSQIIFGLIISDNQFDYKNFLNY
                     ILLPIISLVYIYPFLCEEYGWRSFLQSILFDRFGKKIGIVMVGTCWSLWHLPLQFTLY
                     SPQTPIIGAIAHLIYGIGLSIFLGYVYMKTKNIWFCSIMHVLINSLGLIFNDSEIIIN
                     YHSIIQRLIFILLFYTPFLFTKEYK"
     gene            940..2466
                     /locus_tag="PC366_003508"
     CDS             940..2466
                     /locus_tag="PC366_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2578991.1"
                     /translation="MNESYWFLNSSPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VEQIIEENNIKCDFKRETSFVFTEKEDTIKNIKDEYRTCKKIGINCEYHETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKAAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMVAVLENKLADGMFISIDDPSITFRQY
                     NNGSENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKEVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            2494..3045
                     /locus_tag="PC366_003509"
     CDS             2494..3045
                     /locus_tag="PC366_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578992.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKVFLVIFLFMFSMGVASLWEIGEFLMDTFVGTTTQAGGLED
                     TMIDMVDALIGTIITIPYYSKKI"
     gene            3574..4617
                     /locus_tag="PC366_003510"
     CDS             3574..4617
                     /locus_tag="PC366_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578993.1"
                     /translation="MLKKWFGIVKKRQKSESVKEEGEVILKNEKILSEEKLIDEEGVV
                     VNIDNEILTKVEVVNDDNEIEEKIIEEDWLISENTIKLDDKEAIINDKNIELCKKEVQ
                     VESEKIGLNKFEGLDQNENYNLEKNVIEEKKVSECLTEEDLEYIKEIKIKRGKSIKAI
                     NLYTKEEWVFDTHIQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKG
                     EWSYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYRFECIDEEYD
                     EYFKKYKSIIKRGGKKKVELVNKKGDILEIFKSLEECAIYLQKEKNEVIQMLKYGDTK
                     VGRNFIRYSLRSI"
     gene            4728..5870
                     /locus_tag="PC366_003511"
     CDS             4728..5870
                     /locus_tag="PC366_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2578994.1"
                     /translation="MSEEKNPKENTLDEPKNSDNVNSKKDDVSDEKNTDNKVKKREIK
                     LNNKTLKAIVAIVAVGAICLGGGYVFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKSKVTDKEAEN
                     YYNKNKSNYLQVRASHILIKTVDDKGKQVSSSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEVKSDLVSSLTSEKQNLLIQNLKEKYNVKITDKYQMKAKE"
BASE COUNT         2479 a          500 c         1019 g         1984 t
ORIGIN      
        1 aaataacaag tttatatatt tttaaaaatt ttaagatagg tattttgcta gttttttact
       61 ttttattttc tcaaattatt tttggattaa taataagtga taatcaattt gattataaga
      121 atttcttgaa ttatattctt cttcctataa tatcattagt atatatttat ccttttttat
      181 gtgaagagta tggttggaga tcttttttac aaagtatttt atttgataga tttggcaaaa
      241 aaataggtat tgtaatggta ggcacttgtt ggagtttatg gcacttacct ttacaattta
      301 cactatatag tcctcaaact ccaataattg gagctatagc ccatttgata tatggtattg
      361 gactttctat atttttaggt tatgtttata tgaaaactaa gaacatatgg ttttgctcta
      421 taatgcatgt tctaattaat agcttaggat taattttcaa tgattctgaa ataattatta
      481 attaccatag tattatacaa agattgatat ttatactatt attttatact ccttttctat
      541 ttacaaaaga atataagtaa gaattacaat taatttatat aaaataaatt tttaagtaaa
      601 tatttttata gagagattgt tatattacat atcagaaaaa tattaaacga actaaatcaa
      661 taaaaaagtt ggtggctaac aatttataat tgttagcaca atataatctt atgtattgaa
      721 atctagaata tcctcatttt tacttagcat aaatactatt gattaagaaa ataatataga
      781 aattataaat atatataagt ttagtctggt gtataaaaca agaaaactaa gtgatttttc
      841 atttagcttt ttattaagct tattttttat actatttata ataaataaac tccatgatgg
      901 gaaaactatt actatttaat atgtaaagga gtattttaaa tgaatgaatc atattggttt
      961 ttaaactcaa gtccaaaaga atataacaaa ttaggtgaaa atataaaaac agattgtctt
     1021 atagtaggtg gtggaataac tggattgaca actgcatatt tattagcaaa agaaggtaaa
     1081 aaagtagtgc ttgttgaggc tgataaaata ggatatggaa cttctggaag gaatactggt
     1141 aaggtaactt gtcagcatga tatattttac tctaagatag agaaaaaata tggattagat
     1201 aaagcaaaat catattataa tgcaaataat gaagctttaa atttagttga acaaataata
     1261 gaagaaaaca atataaaatg tgattttaaa agggaaactt cttttgtatt tacagaaaaa
     1321 gaggatacta taaagaatat taaagatgaa tatcgtacat gtaaaaaaat aggaataaat
     1381 tgtgagtatc atgaaactat agaaaatatt ccattagata taaagggggc tattagtttt
     1441 actaatcaag gtcaatttaa cccaaagaag tatattgatg gattggcaaa agcagcagta
     1501 aatttagggc taaaaatata tgaaaataca ccagtagtag atcttgaaaa aggaaaaata
     1561 tgtagggtta aaacaagaga agataatata atagaagctg agaatgttat aatttcatct
     1621 catagtccat ggtatgatgg attgaatttt tattttgcaa aagaatatgc agagcgtgct
     1681 tatttaatgg ttgcagtttt ggaaaataaa ttagcagatg gtatgtttat aagtatagat
     1741 gacccatcaa taacttttag acaatataat aatggaagtg aaaatttact gatttttgga
     1801 ggaggagacc ataaagttgg ccagggagga actgagaaag aaatatttga tgatttagag
     1861 cattatggta aagaagtctt taaggtaaaa gattttaagg ggaaatggtc tgctcaagat
     1921 aatatgagtt ttgacaatgt tccttatatt ggttatatca acaaaagaga agacaatatt
     1981 tatgtagcta caggattctc taaatgggga attactaatg gaactgctgc tggaataata
     2041 ataaaagatt tgataataaa taataattct gattataaag atacttttaa tccatccaga
     2101 ttaggtagct acttttcaaa agattttata aaggaaaatg caaacgtagc aataaattat
     2161 gtaagtggaa aattaaaaat aggtagtgga gatatgccta aaaataatgg agaaggaaag
     2221 attgttaata ttgatggaaa aagatatggt gtatataagg atgataatgg agatttttat
     2281 attgtagaca cgacatgtac tcatttagga tgtgaactta attttaacag tgaagaaaaa
     2341 acatgggact gtccatgtca tggttctaga tttgactata agggaaatat acttgaagga
     2401 ccagctctta agccattaaa actttatgga catggtgata atgatgttaa tcctaagtta
     2461 ttataaaatt atttttagga aggtaaagtg tatatgaata aacttttaaa gccaataact
     2521 atactattgt atatagttta tattttatct gccgtatttt ttgtagcaaa caaagaatat
     2581 ggaagtctag gtctagtagc aattagttta gttggtactt tcattttgag ttttataaat
     2641 aagcaaactg aaagattatt gagtaaagaa ttatatataa tgcttgcttt atttataatg
     2701 ttttcatcat tgttaggtac ttgttttaat ttttatgata taaattatta tgatgatttt
     2761 ttgcatttat ggtcaggtat aatatcttgt attgtggctt tttctataat taaatacttt
     2821 tatacacaaa gagagataag taaaatgagt aaagtgtttt tagttatatt tttatttatg
     2881 tttagtatgg gagtagcgag tttatgggaa ataggtgaat ttttaatgga tacttttgtt
     2941 gggactacta cacaggccgg ggggttagaa gatactatga ttgatatggt agatgcttta
     3001 ataggcacaa ttataactat tccttattat agtaaaaaaa tctaatatat agttttaaat
     3061 tttttatatt aattataatg gatttaatta atcatgttga gtttcaaggt ctatatgatt
     3121 aattaaatcc atttttgtta tttataatta ttattgaatg tatttttaca tataagatat
     3181 aaggtgatag atagaaattg ttggattatg taaataatta atatataata ccattatggg
     3241 caataaatac aaatcaaatg ataatatagt ctatttatgt aaatgttata ttgtatccta
     3301 agtataatag taagtttttt gatagtggtg tagaaagtaa aaatctacta gcctaaattg
     3361 atgtatggat tagtttagga acagtaattg catatcttaa gtttgatgtc atgttgggct
     3421 actagaaata ggtcatcttt ttcacttgaa tatcttttct ttaaacatga ggagtatcat
     3481 atcaaaaaca tatgaaaatt aagtgattta taagaacagt aatattttat atgatagtat
     3541 agaatagtaa taaagtatta ggaggaacat tgagtgttaa aaaagtggtt tggtattgtg
     3601 aaaaaaagac aaaaaagtga gtcagtaaaa gaagaaggtg aagtaatatt aaaaaacgaa
     3661 aaaatattat ctgaagaaaa gttgatagat gaagaaggag ttgtagttaa tattgataat
     3721 gaaatattaa ctaaagtaga agtagtaaat gatgataatg aaatagaaga aaaaataata
     3781 gaagaagatt ggttaattag tgaaaatacc ataaaattag atgataaaga agcaattatt
     3841 aatgataaaa acatagaatt atgtaaaaaa gaagttcaag ttgaaagtga aaaaataggt
     3901 ttaaataagt ttgaaggact tgaccaaaat gaaaattata atctagaaaa aaatgttatt
     3961 gaagaaaaaa aagtaagtga atgtttgaca gaagaagatt tagagtacat aaaagaaatt
     4021 aaaataaaaa gaggaaaaag tataaaagct ataaacttgt atactaaaga agagtgggtt
     4081 tttgacactc atatacagtg tagtaaaaaa ctcaaagttc cattaggata cataagagaa
     4141 aatttaaaat atggatatat ggattacttt ggagatgcaa taaattattt aagtgaagta
     4201 ttaaatatag atgaatactg caaaggtgaa tggagctatc tcgataatag caaatctcca
     4261 tctgagatat ttaatattct aaacaataaa atatttagta taaggctttc taatgaaaaa
     4321 agaaatgaaa ttttgacaaa tgataaaatt gaagcattaa aaatgaatta tagatttgaa
     4381 tgtattgatg aagaatatga tgaatatttt aaaaaatata agtctataat caaaaggggt
     4441 ggaaagaaaa aagttgaatt agtaaataaa aaaggtgaca ttttagaaat atttaagtct
     4501 ttagaagaat gtgccattta tttgcaaaag gaaaagaatg aagttataca aatgttaaaa
     4561 tatggagata caaaagtagg aagaaacttt ataaggtata gtttgagaag tatttaattt
     4621 cattttaaat tcataagagt ttcatttctg attcacacat ttaatattat tttaatgtaa
     4681 aataataaag gtgaagtatt gcacaattaa aattaaggag ggtattaatg tctgaagaaa
     4741 aaaatccaaa agaaaataca ttagatgaac ctaaaaattc agataatgta aattctaaaa
     4801 aagatgatgt gtcagatgaa aaaaatactg ataacaaagt taaaaaaagg gaaataaagc
     4861 taaacaacaa aacacttaaa gctattgtag caattgttgc agtaggagct atatgtttag
     4921 gtggaggcta tgtttttggt aaagaagctg gaagaaaatt gcctgctact tcaaaacact
     4981 ataatagcag tgaggtagta gctactattg gggataaaaa aataacaggt gaaatgttaa
     5041 gaaagagaat ggagccatta ttttatttaa atgcaaaaac tactatgact gatgacgaaa
     5101 tacgttcata tgaatcaaat atgattgaaa ctatgattac atctgatata ttatcctctg
     5161 aagcagcaaa agagaaaata agtataacta atgaccaact agatgctcag tataataatt
     5221 taatgagtag tatagaatca gcaatgggaa tgactaaaga agagttttta aaacagtttg
     5281 atttgactga aaaatatata aaagatgata tgaaaaaaga gctagtagca tcaaaatatt
     5341 taaatgaaaa atcaaaagtt actgataaag aagcagagaa ctattacaat aaaaacaaga
     5401 gcaattattt acaagttaga gcttcacata ttttaataaa aactgttgat gataaaggta
     5461 agcaagttag tagtagcaaa aaagctgaac ttaagaaaga agctgaagaa atacttaaaa
     5521 aagcccaagc tggggaagat tttgctactc tagctaaaaa atattctgaa gatagtagtg
     5581 cagaatcagg tggagattta ggtttctttg gtaaaggtca gatggtggaa tcttttgaaa
     5641 aagcagcctt tgcattgaag aagggagagg tatctaacaa acttgtagaa agtgattatg
     5701 gatatcatat aattaagaaa actgatgaaa aatatcaacc atttgaagag gtaaaatcag
     5761 atttagtaag cagtttaaca tcagaaaaac aaaacctact tatacaaaat ttaaaagaaa
     5821 aatataatgt taaaattaca gataaatatc aaatgaaagc taaagaatag ataaagtcaa
     5881 tttattaaaa aaaagaaaaa ttaactgtat ggataaaagc tatttttact ctcaatatag
     5941 agagtctaaa gtagctttta ttattttgta ataaaatcta tt
//
LOCUS       DAMJWO010000140         5840 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.145, whole genome shotgun sequence.
ACCESSION   DAMJWO010000140 DAMJWO010000000
VERSION     DAMJWO010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5840
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.145"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            138..1319
                     /locus_tag="PC366_003512"
     CDS             138..1319
                     /locus_tag="PC366_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2578995.1"
                     /translation="MNKKYIKAGNLIDGTGNSIMQNKGIIIDGDTIVEIEDIRDDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKIYYDNVSDVELVVNTIKQVDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVNGNPVENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(1461..2378)
                     /locus_tag="PC366_003513"
     CDS             complement(1461..2378)
                     /locus_tag="PC366_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578996.1"
                     /translation="MENNKCREDFRFTQEYEEDYPNTNERYYENYQVADRYYNYPNKY
                     KEPKIKQCCCKKSMREALELLRYDALRPFVNFNQFAFISDFFIVGANLVGIDLSAPPK
                     DNLSGLDGTFERFSACNCDLIDIAGRVSYPIPVPLTLEGLINTIGTIPGVAELIALID
                     AVIPPTIDLGAILDAILAAIIDFILAASTPLANVDLASLCNLKAVAFDITPADYEDFI
                     ASLGYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVIVLGNSNDSRIYFVCVDSIDYIA"
     gene            2631..3425
                     /locus_tag="PC366_003514"
     CDS             2631..3425
                     /locus_tag="PC366_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2578997.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKVKTKKEEFFAVNNVS
                     FKVMEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINISGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEDIEESIENIVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGKIIASGTPQSLKEESGVNNLRDVFIKLARKEDI"
     gene            3426..5486
                     /locus_tag="PC366_003515"
     CDS             3426..5486
                     /locus_tag="PC366_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2578998.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKDTKNTSNDKGKIRVLDVDNYK
                     KSLEENKIDAYIKMEEKKSSINYQIYINSSQENSSNALKRIETVLDKYKRFTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMAFILVSGGISSQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLVLLIYVGSLVQ
                     IKFGMAGIIMTQFMIISLPLLFACYIKADFKEVFSLTVPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQNMEVAESLNKALFIKDSVLLNLLAIALLPAICEELFFRGFIFSSF
                     SKSKDKNKSIKLAIICSGVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSMLLH
                     FLNNSVAVVLNHYTTGNITNLYKFVEVDFSNLNVLKFALILLISLILIMLGLRVLDRK
                     SLRN"
BASE COUNT         2253 a          644 c          946 g         1997 t
ORIGIN      
        1 gtataattat aacaatttaa tttatattaa tgcacttaaa tttgaaatag aatgcttata
       61 gtggtaaaat taattattag aatattagaa ataataaata aataatacat tgtacttaaa
      121 agggggagaa atttaagatg aacaaaaaat atattaaagc agggaattta attgatggaa
      181 caggaaatag tattatgcaa aataagggta taattattga tggagatact atagttgaaa
      241 ttgaagatat aagagatgat ttaaatggat atgatgtgta cgattactta gataaaactg
      301 ttatgccagg cattatgaat tgtcatgttc acttgacaat ggagccagtt ggaaatccaa
      361 agatatatta tgataatgta tcagatgtag agcttgtagt aaatacgata aaacaagttg
      421 atgcttattt ggattcagga gtaacatata ttagaagctt aggttgtccc aaatatgtgg
      481 atgtacaact taaaaatctt atagacaaag ggtctataga tggtcctggt atagttactt
      541 caggtccagt tatatgtatg acaggagggc atggatatta ttttggtatt gaaagtgatg
      601 gagtggatga atgtagaaaa tcagccagaa cagttttaaa aaatggagta gattgtgtaa
      661 agataatggc aactggaggt gtaacaactg atggagttga gccagggtca ccacaattaa
      721 ctttggagga aatgaaggct gctgtagatg aagctataaa agcaggtaaa ataactgcca
      781 cacatgcaca aggaagaact ggtataaaaa atgcagttct tgcaggaatt acttctatag
      841 aacatggtgt ttatttagat gatgaaataa ttgatttgat gcttgaaaga ggaacttact
      901 tagttccaac tgtggctgca ccatatttta ttctaaatgc aggaaaagaa agtggaataa
      961 ctgaagctac tcttagaaag tgtgagattg ttgccattcc acataaagaa tcattcctaa
     1021 aagcatataa aaaaggaatt aaaattgcag ttggttctga tgcaggaact tcttataatg
     1081 aacatggaaa aacatattat gaaatgaagc taatgtcaga ttatggtatg gataatatgg
     1141 atataatagt tgctgctaca aaaacagcat ctgaactttt aagaattgat aaaaattatg
     1201 gaactctaga aaaaggaaag aaagcagatg ttatagttgt aaatggaaat ccagtagaga
     1261 atatagacgt acttgcagat gtgttagcag tatttaaact tggtaaaaaa gttagataaa
     1321 tagtataaaa ataaaaaaga gtgtctaaag aaatttttaa ataattatag acactctttt
     1381 ttattagtaa taattaaatc ttttatactt tagaaaatag attctatttt atatttagat
     1441 ataactcttt aaaatcattc ttatgcaata taatctatag aatctacaca tacaaagtat
     1501 attcttgaat cattagaatt tccaagtact ataacatcat ttttcttacc tagaacttca
     1561 acaccagtta gaaccaaact accagctact acagtaactt gattatttat atttgacata
     1621 taaagattat ctaggatacc tttattacaa cagcaatcat cacaatcgca gttacaatta
     1681 cattctttgt aatgtttttt atcaagatag taacctaaag atgctatgaa atcttcataa
     1741 tctgcaggtg taatatcaaa tgcaacagct ttaagattac acaatgatgc taaatctacg
     1801 tttgctaatg gagtagatgc agcaagtata aaatcaatta tagcagcaag tattgcatct
     1861 aatatagccc caaggtctat cgtaggagga ataactgcat caataagtgc aattaattca
     1921 gctactcctg gtatagttcc tatagtatta attaatccct caagagttaa agggactgga
     1981 ataggataag atactctacc agctatatct attaaatcac agttacaagc agaaaatctt
     2041 tcaaaagtac catcaagtcc agataaatta tcttttggag gagctgaaag atctatacct
     2101 accaaattag cacctactat aaagaaatct gagataaaag caaattgatt aaagtttaca
     2161 aaaggtctta gagcatcata tcttagaagt tctaaggcct ctctcatact ttttttacaa
     2221 caacattgtt ttattttagg ttctttatat ttatttggat aattatagta tctatcagct
     2281 acttgataat tttcatagta tctttcattt gtatttggat aatcttcctc atattcttgt
     2341 gtaaatctaa agtcctctct acatttatta ttttccacta aatacactcc ttttatattt
     2401 taatttaaat gtatagataa ttaagcttat ctatatagta atattatatt tataatgtaa
     2461 aaaaatgtta caaaagatat tataaacgaa taaaaaataa taatttgtca gataaacttg
     2521 taaattttta tgaataatcc attctaaaac aaaaaactgt gtataaaaaa ggtttatatg
     2581 ttatatttat ataaatataa catatgaacg agaaaggagt ggtttgataa atgattgagg
     2641 tagataaatt gtgtaagtct tttacaaggg ttgtaaaaga tgataagaat aaaagttcaa
     2701 taagaaagct aaagaaagta aaaactaaaa aagaagaatt ttttgctgta aataatgttt
     2761 catttaaagt tatggaaggt gaaattgttg gaatattagg tccaaatggt gcaggaaaga
     2821 ctacattact tagaatgtta ggtggcatat taacaccaac atcaggaagt ataaatattt
     2881 ctggatatga ttattcaata gatagaaatt cagcaaaaaa agaaataggt tatctctctg
     2941 gaaatacaaa actatatgga aggctttctc cgagagaact tctaacaact tttgcaagtc
     3001 tatatgagat gtcaaaagaa gatatagaag aatcaattga aaatattgta aaaataatgg
     3061 atatgagtga atttatagat aatagaattg aaaatctatc aactggtcag actcaaagaa
     3121 catctatagc ccgttgttta atacattctc caaaagtata tatttttgat gagccaacac
     3181 taggtctgga tgttttaagt agtgcatcta ttatagattt tatgaagaat gaaaaactaa
     3241 gaggaaaaac tgttctttac tcaactcatt atatggaaga agcagaaact ttatgtgaca
     3301 agatttttat gattcacaat gggaaaataa ttgcatcagg aacaccacag agtttaaaag
     3361 aggaatctgg agtaaataat ttgagagatg tattcataaa acttgccaga aaggaggaca
     3421 tttaaatgag aagtaagatt gtaaaataca tatttaaaaa agaaatgtta gacatattga
     3481 gagataaaaa gactttattt atgatgattg ttgtgccact tcttttatat cctttactta
     3541 tgttattaat gattcaagta atgaatatgt ctgcaagtag tatgaatagt aaggacatta
     3601 atatagcttt taataataaa cctaataagg tgttagtatc catgattgaa gatgataatt
     3661 tagaaaaaga tactaaaaat acttcaaatg ataaaggcaa aataagagtg ttagatgtag
     3721 ataactataa aaagtcatta gaagaaaata aaattgatgc ttatataaag atggaagaaa
     3781 aaaaatcatc tataaattat caaatatata taaattcttc tcaagaaaat tcttctaatg
     3841 cactaaaaag aattgaaact gttttggata aatataaaag atttaccata gaaaaaactt
     3901 tatctgaaaa aggattagat gtacaagcta ctttagaacc aataacatat agcactgtag
     3961 atgttgcaaa gacggaagaa gtggcaggat actttttagg tcagatactt ccatttatat
     4021 taataatagg agttttacta ggttcaatat atccagcaat agatgttatg gctggagaaa
     4081 aggaaagagg tacattagaa acattattta cactcccaat atcaaactta gaactggtta
     4141 tgggaaaata tatggcagtt tctcttagtg caatagtaac agcaatttta aacattttat
     4201 ctatgggact gactatggca tttattttag ttagtggagg tattagtagc caatttggct
     4261 ttggaaactt taattatgga gacttagtct taccaattat aactacttta atttgcatat
     4321 gtcttttttc aatggtagtt tcagcaataa gtatgtgtgt atgttcatta gcaaaaagtt
     4381 ttaaagatgc tcaaaactac ataacacctc ttatgttaat tattatgata ccatcatatg
     4441 tttctatgat accaaatata gtattggata gagtgacagc tgtaatacct gtagtaaata
     4501 tatctttact tataaaaagt gtattatctt ttaaaagcga tttaaattta atagccttag
     4561 ttttagcatc aaatgtagcc tttgttatat tggcaatcat actactgtct aagatgttca
     4621 attctgagga aatacttttt ggtaatagta agagtttttc tttcttagag aaaagaagta
     4681 atataaaaaa agggtctata ccaactgtaa gtgatggtgt tattttatat gcagtaggat
     4741 tagttctatt gatttatgtt ggttctttag ttcaaattaa atttggtatg gcaggtatta
     4801 taatgacaca attcatgata atttctttac cattattatt tgcatgctat attaaagctg
     4861 attttaaaga ggtatttagc ttgacagttc ctaaattaaa gcatgtgttt gggagcattg
     4921 ttctttggat tggtggatac atacttatta tgattataac acagctaatt ttattcttat
     4981 ttcctcaaaa tatggaagtt gctgaaagtt taaataaggc tctttttatc aaagatagtg
     5041 ttttactgaa tttactagca atagctttat taccagctat atgtgaagaa ctgtttttta
     5101 ggggatttat attttcttca tttagtaaat caaaagataa aaataagtct atcaaactcg
     5161 ctataatatg tagtggggta ctatttggta ttatgcatat ggattttatt agaataattc
     5221 caacatcaat attaggtatt atatttgcat acagtgtgta taaatctggt tcaatatttg
     5281 tatcaatgtt attgcatttt ttaaataata gtgtagcagt tgtgttaaat cattatacaa
     5341 ctggaaatat aaccaactta tataaatttg ttgaagttga tttttcgaac ttaaatgtac
     5401 ttaaatttgc cttaattctt ctaataagtc ttatattaat tatgttagga ttaagagttt
     5461 tagatagaaa gtctttaaga aattaagtat aaagttatta tatagattaa aatattaata
     5521 agcactaaag tatatggata tatcttgtat ataaaaatac tttagtgcta ttttatatat
     5581 tttaattata tgaattattt atcgtttcat ttatgtaatg aaaatgttat ataaatgaaa
     5641 caataaataa tttttatttt agaaatttat atttaaataa tcaagttgaa agtgagatac
     5701 taaaaaaatt aatttaggaa ttatttgatt tattcattta taaaaattaa ttactgattt
     5761 gtcgaaacca ttgtaataag aaaaaaatga aaaaataaag tgtgaatatg ttgcaaatac
     5821 tgtattttaa taaaaagtag
//
LOCUS       DAMJWO010000141         5741 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.146, whole genome shotgun sequence.
ACCESSION   DAMJWO010000141 DAMJWO010000000
VERSION     DAMJWO010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5741
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.146"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            244..426
                     /locus_tag="PC366_003516"
     CDS             244..426
                     /locus_tag="PC366_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2578999.1"
                     /translation="MFKDKIDECVHIMTAYIASLKEYYSFIETQIGDFIKKYGEDVVE
                     LCLHRVMILLCECGLA"
     gene            complement(714..916)
                     /locus_tag="PC366_003517"
                     /pseudo
     CDS             complement(714..916)
                     /locus_tag="PC366_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003381593.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
     gene            1258..2172
                     /locus_tag="PC366_003518"
     CDS             1258..2172
                     /locus_tag="PC366_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HDF2579000.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKDITT
                     RELNLQSGVNPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPL
                     LLEHIIHEANLYRSYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
     gene            2562..3209
                     /locus_tag="PC366_003519"
     CDS             2562..3209
                     /locus_tag="PC366_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HDF2579001.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTAFKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEMGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(3376..3945)
                     /locus_tag="PC366_003520"
     CDS             complement(3376..3945)
                     /locus_tag="PC366_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579002.1"
                     /translation="MKKFILCIIMFAISVLVLAGCTNDNKIKNEVDSMFNSIKTQDAD
                     TVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSIL
                     KKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITG
                     GGIDYLADYNKDYYKQLDEEQKNYENKNS"
     gene            complement(3950..4849)
                     /locus_tag="PC366_003521"
     CDS             complement(3950..4849)
                     /locus_tag="PC366_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDF2579003.1"
                     /translation="MKLLSKVNNNIRLIIQVAFTALTNGYVNGFLEGTIYGGESKKLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLIMFVIILPVAIVNVAGGGNPWFCKW
                     ICPSGTLLGGIPLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGA
                     IYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQN
                     AITTTFSKDKKENNICAKKYRGI"
     gene            complement(4860..5009)
                     /locus_tag="PC366_003522"
     CDS             complement(4860..5009)
                     /locus_tag="PC366_003522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579004.1"
                     /translation="MSNFIKDNKKGISIIAISIIFIALGTYRGETNTVLTKAIMICLE
                     CIGIG"
     gene            complement(5002..5586)
                     /locus_tag="PC366_003523"
     CDS             complement(5002..5586)
                     /locus_tag="PC366_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HDF2579005.1"
                     /translation="MKKFFMVVLGCIFVLGVISGCSKKESKPVEKNKSNSEWFSNLDT
                     EDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLV
                     VEVDKTDMRTGLSNEEKNLVKNIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVD
                     KKGNFVGEKVVGANSKEEWKKIIDERLKMVKANE"
BASE COUNT         2102 a          866 c          662 g         2111 t
ORIGIN      
        1 ttacacttat attaatttat attaaatatc tactaactca aatattcata attaaacttt
       61 aaactggata aattttcttt taagaatgaa agtttatcca gttttgcgat tataataacc
      121 agttttacat atccacttgt aaaatatatc taagcaatat atcatactat atagatttat
      181 gagtgaaata atatctgcta tttactgaat atttttattt ttcgtttttt agggggatta
      241 gttgtgttta aagataagat tgatgaatgt gttcatataa tgactgcata tattgctagt
      301 ttaaaagaat actattcatt catagaaact caaattggtg attttattaa aaaatatgga
      361 gaagatgttg tagagttatg tctccataga gtgatgattc tactatgcga atgtggtttg
      421 gcataaaatt aaatttatta aaatgggtaa gaagaatcct atataatatt cttcttaccc
      481 attttaatat atcaatttca tagcttatcg tttaaaatat tttacctcca ttactagaca
      541 actttacatt ctctttttaa ttctagtata tttaaatcat tttagttgct ccttatttat
      601 tcttattact tgttttattt tataaataaa ataattcttt ttaataatgt tttttgttga
      661 tattcctatc acacatccaa ttatttatca ttgtcttgaa attgtttgca tacttaattt
      721 aatccaattg aaacacccca gcatagaatc ccctgtaaaa tagaagttgg attaaatcct
      781 aacatccata cagaaaatac tactccaagc acaagcaata taatggaata tatttatcac
      841 ttaatttttt atacttttta aatcccatac ctaaaacatt aagtgcagct attagaatta
      901 ataattgttg tggtataaaa ttatgattgc ttcatattta ttcatttttt gctataaaag
      961 ttcttgtttc acaaaaaata tttgttttgt atcaaaataa tacttataaa ttacataatt
     1021 ctcataaaaa tttctagtat tacttgtgct cttaataaat aatagccaac aagtacctta
     1081 aatcattata tctatatcta ataagaaaca cagtaagata attttttcgc ccataactta
     1141 ataaaaactg ttgatattag tagcaattga atttagttaa tttatttata atatacataa
     1201 atttaaatat tacgaataaa gtattataaa taggatactt tctaaaggga ggaaattatg
     1261 atagataatc aaaaatatgt tattttatca ctagaattac atttattttt ttcaagaatt
     1321 atgaaagagc atgctctttt tttagaagca ggattcacaa ataaaaatta taatcttgct
     1381 atggaagctg accactataa aaagcaattt gaagatttat tatcatacac tgttagtgct
     1441 agtaatggta taattagacc tgatatatta tattcagaag agcttgtaac tactctcaca
     1501 tcagttgcag aacaaaaaac agaagagttt acagggatag aaataaacaa agacatcact
     1561 acaagagaat taaatctaca aagtggtgta aacccacaag ttggtcaaga cttagtgaac
     1621 tatgtagctc aacttaactc tgatgcaata agattacttg atgggcttat taattttaaa
     1681 gaaagagtct tagatggtgt actatcatgt actatattta catcaaacta ccctctactt
     1741 cttgaacata taatacatga agcaaattta tatcgttctt atgtagttga ccttgaaaat
     1801 aaaatagata ttgagtcaaa aaacgctaaa gaaatagaat tattctggga ccatattatg
     1861 atggaacatg ctctgtttat gagaggatta ctagacccct cagaaggtga actaataaat
     1921 acttcaaatg attttgctat aaaatttaat gaattaattg aaaaaacaaa cgaaatgact
     1981 gattctaata tcaagaacat tacagaagaa actctaaatg aaactgttga gtttaaagat
     2041 tttaaagaag caggagcatc aggaatagaa cagtgtaaga taaaatctat aatattacca
     2101 cttttagcag accatgtttt aagagaggca aatcattata ttagaatatt ggagagttat
     2161 aaaaacatgt aattaaaaat tacttttaaa ataatctttg catatttaga taaaataaag
     2221 gtacagttaa ctgtaccttt attttttata aacttataaa atttaaacaa gttattcata
     2281 aaataaaata atcatcatct ataacccaca actttatttt atattaaata aaaagtatta
     2341 gtgattatgt tttataagta tttctttatt cagttatttg ttaaaaacta atagtaaatc
     2401 ttatactaat cgcatattta tgttataact atattgtaac tattttcgta atcttaggaa
     2461 aagattactt ataaaattaa ccttatacaa taatatatcg tataatctta attagcataa
     2521 tagttacaat attaaaattt aaatatggga gtgattttag tatgataaga caaacaccat
     2581 tagagaaacg atatgacaag ctaggtcctc atattgtaac agcattcaaa aaacgttatt
     2641 ttgatgctta ttactgtaaa actagaaatg aagctttgca acaaatttta gatttaattc
     2701 ctcaaaatca tgtagtatca tggggaggat ctgaaacact taaagaaatg ggcgtacaaa
     2761 ctgctgttag agagaaagga tttaaagtta ttgatagaga tttagcaaaa actccagaag
     2821 aaagaactga aattatgcgt caagcacttc tatgcgatac ttttttgatg agtagcaatg
     2881 caattagtga agatggacaa ctctttaata ttgatggaaa tggcaatcgt gtagctgcaa
     2941 tgatatttgg tccaaaaaat gttatagttg tagctggtat gaataaaatt gtaaaaaaca
     3001 ttgatgatgc aatacaaaga actagaacaa ttgcatctcc agcagttgtt cagcgttttc
     3061 aagatgtcaa tacaccatgc tatattaatg gaagttgtat agattgcaca agtcctgaaa
     3121 gcatttgtgc atacatggtt actacaagaa tcagtcgtcc agcaaaaaaa ataaaggtaa
     3181 tattggtagg agaaaatctt ggtctataaa atatacatac atgtaaatag ctctataaat
     3241 aataaaatca tatgaaataa cttatttcta aaagtggtag aataaaagct tctacaagac
     3301 tttcattcta ccacttttat attcttttaa tttgtgtttc tatattatta attgctccaa
     3361 ttttcatata tattactaac tatttttatt ttcataattt ttttgttctt catcaagctg
     3421 tttataataa tctttattat agtcagctag ataatctata ccacctcctg taatcacatt
     3481 taataatttc attgcagatt cttgattaac tttacaaaca taattatcac cagatttaac
     3541 aagctctaat gtaatattaa attctttttt ctttgcagaa tcaatatctt tcatagttgg
     3601 atttggcatc atttctccta gtttaggagg attctttttt aaaatagaaa ccatatcagt
     3661 attgttaatt tttaaatcta cagtcacttt atccttatta ttctttatat ctgaaatttc
     3721 ccaagtcata tttttagaat acattttaaa tccttcttta tcttcgtata taagattacc
     3781 taaccctgat tttgggaaat acttatcaac agtatctgca tcttgtgttt ttattgaatt
     3841 aaacatacta tccacttcat tttttatctt attatcatta gtacaaccag ctaacaccag
     3901 tactgatatt gcaaacatta taatacatag aataaatttc ttcattaaat tatatccccc
     3961 tatacttttt tgcacaaata ttattctctt ttttatcttt tgaaaaagtt gtagtaattg
     4021 cattttgtgg acaaactttt atacattcac cacacctaat acagtctgga ctatttacat
     4081 ctttatatat tggtatatca agcttacatt ttgtttgaca tgctgtacaa tttgtacatt
     4141 tatctttatc aattttaaat ctatatattg aaataggatt aaaaaaacca tagattgctc
     4201 ctaaagggca tatatacttg caaaatggcc tataagtaat gattgacatc aataatatca
     4261 atagcaaaat acttaacttc cagctaaata aaaatcctat tgattctctt aaattctcat
     4321 ttcctaaaat aagtggtatt cctcccaaaa gtgttcctga agggcaaatc catttacaaa
     4381 accaaggatt tccaccccct gctacattta caatagcaac tggcaaaata attacaaaca
     4441 ttattaagac tatatacttt agatatttta gatatttatc accataaact ttttttatct
     4501 ttactggaaa gggtacttta tgtagtaaat cttgtacaag tccaaaggga caaagccaac
     4561 cacaaacaaa tctgccaaaa aaagcaccaa atgccattaa aaaaccaaca acataaaatg
     4621 agaatttata ctctctgctt gataaaactg cttgtaatga acctattgga catgctccaa
     4681 gtgcacctgg acatgaataa caattcaatc caggtacaca taatttttta ctttctcctc
     4741 catatatagt tccttctaaa aatccattta catatccatt tgttaatgct gtaaatgcaa
     4801 cttgaataat aagtcttata ttattattta ccttagataa taacttcatt cctcttctcc
     4861 taaccaatac caatacactc aagacaaatc ataattgctt tagttaatac tgtatttgtt
     4921 tctccacgat atgtacctaa tgcaataaat ataatactaa ttgcaataat agaaatgcct
     4981 tttttattat ctttaataaa gttactcatt ggcttttacc atttttagtc tttcatctat
     5041 aatttttttc cactcttcct tactatttgc acctacaacc ttctcaccca caaagtttcc
     5101 tttcttgtct acaaaataag ttgttggaaa ctccataact cttttaaaat cagttttttt
     5161 aagttcttca gatacagtca attgttggta agttgcatct gactttttca taatgttttt
     5221 aactaaattt ttctcttcat ttgaaagacc agttctcata tcagttttat caacttctac
     5281 aactaatccc tttatagcta cattggaatt attactctca tattcttttg ataatgcttc
     5341 aagctctggc atttcaccca cacatggtcc acaccaagta gtccagacat taataagagt
     5401 aagttcttta tttgaaaata tctcttttgt taccttattt ccatcaacat cctccgtatc
     5461 taaattacta aaccattcac tattactctt gtttttttct actggcttag attctttttt
     5521 gctacatcca gaaatcacac ctaaaacaaa aatacatcct aaaactacca taaaaaactt
     5581 tttcatatct cacactccta gaatttatat agtatataaa atggctgctt gaaataaaaa
     5641 taacttctct tctatattaa aacattatat ttaataaata agaactaatt taaaataagt
     5701 tgtataaaag atatatagtt aaaatctatt tcttttcaga c
//
LOCUS       DAMJWO010000142         5682 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.147, whole genome shotgun sequence.
ACCESSION   DAMJWO010000142 DAMJWO010000000
VERSION     DAMJWO010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5682
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.147"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(269..952)
                     /locus_tag="PC366_003524"
     CDS             complement(269..952)
                     /locus_tag="PC366_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HDF2579006.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKTKIHWRQVIIIIEMI
                     TILIVSFIPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAIIIFFISGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
     gene            complement(1294..1884)
                     /gene="zapA"
                     /locus_tag="PC366_003525"
     CDS             complement(1294..1884)
                     /gene="zapA"
                     /locus_tag="PC366_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HDF2579007.1"
                     /translation="MNKVMVKIHGAEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAETKMKELIEIIENKKQEIFELSNTTEGSRAELDVYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDAKNVE"
     gene            complement(1909..4302)
                     /locus_tag="PC366_003526"
     CDS             complement(1909..4302)
                     /locus_tag="PC366_003526"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HDF2579008.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     KDALIDFELTSNRPDCKCMMGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRNAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITSN
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVANDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNAKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFALKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEDVAKVHDKILSELSEKLNANLRSN"
     gene            complement(4319..5338)
                     /gene="pheS"
                     /locus_tag="PC366_003527"
     CDS             complement(4319..5338)
                     /gene="pheS"
                     /locus_tag="PC366_003527"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HDF2579009.1"
                     /translation="MQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     misc_binding    complement(5388..5622)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT         1736 a         1098 c          607 g         2241 t
ORIGIN      
        1 taatttatat actgcttact aaatttaaaa cattttaatt aatttgtaca ctgtttacta
       61 tacttgaaat acttctatta atctatatat tgcctactat acttaagaca ttttaattaa
      121 tttatacact gcttactata cttaaaatac ttctattaac ttatatattg cttactatat
      181 tttaaattct ttaattaatc tatacaatat ttgctatata taaagtatat caaataacag
      241 cttcattttt ttgtaaattt acagaaagtt aattttcatt aaatgaatca tctttattga
      301 taaacataat tccaaagacc actgccaaaa taaaaaaaca tattagtatt gatttttcca
      361 cgaaaatttt tgtaaaaaaa gttcctaaaa tagctccaga tataaagaat ataataatag
      421 cataatactg taaactcttt tttatcataa aaatattctt agtatgtata taatgaaata
      481 aagtttctgt agcacttctt aaatttccag tacacattgt cgttgcaaaa ctattcccat
      541 ttacttttct aaaactctct acttgcattg aacaaataaa agaaatagca acatttacaa
      601 acatattaaa tcttcctcta ggaataaatg aaacaataag tattgtaatc atttcaatta
      661 taatgataac ctgacgccaa tgaatctttg tcttattatt tgtaaaatac tttcttatct
      721 tctcggctat aaatacacct aacataaatg ccaaaatagg aatcaaataa taaaatgatt
      781 cctttacatt accttctgct atattaagcc caaataaaac tatatttcca gtttgtgcat
      841 tagcaaagac tttacctctt accacataag tataaatatc caaaaatcct cctgttattg
      901 ccaacaaaga acataaaaag aatgattcag acatctgact cttgcttgtc atatataaac
      961 ctctcgcttt ctaatgatag atacaaaatc aaaatcattt tagattctat ttttcattga
     1021 tataaaaaaa ttatttatat ttaaatatta tctatattta tacatcattt atatttatac
     1081 attatttgta tttatatatc attcatattt atttatattt aaacattatc tatatctata
     1141 tagcatttat atttatttac atttaaacat tatctatatt tatatagcat ttatatttat
     1201 ttacatttaa acattagcta tatttatata gcatttatat ttatacatta aaagaagctg
     1261 tctcaaaaaa caagagacag caaatctttt agtttattcc acattttttg catcattatt
     1321 taaccctgta cattttaact gtaaatcata agctttgttt tgaaactcag aagctaagtt
     1381 ttcagctata gtagctcttt catttgcttc ttcaagttga gtacttaact cctcaatctt
     1441 gtttttataa acatctaact ctgctctaga accttctgtc gtattactaa gttcgaatat
     1501 ttcttgcttt ttattttcta taatctcaat taactctttc atcttagtct cagcttcacg
     1561 attttctgct tctttttctg ctatcgtaag ctttaaagac ttgatttcta attgaagctc
     1621 ttcattagat gctccaacct tcttactcaa ttcttcatta gctttaatca acttctcatt
     1681 ctcatctgaa cattcaaata aaaggtctga tatatttaat gcagttagta tcgcagcaac
     1741 tgataagctc aatttcgggt tttgacgtgt tattttatcc atttctttgt ctacaaaatc
     1801 agcaatacta atcataaact tctctgattt gtctccaacc attggatatt cagcgccatg
     1861 gattttaacc attactttgt tcatcctaac ctcccccgac attagttgtt aatttgatct
     1921 taagttagca tttaattttt cgcttaattc acttaatatc ttatcatgca ccttagctac
     1981 atcttcatct gttagagttt tatctttact tctataagtt attgaatacg caattgactt
     2041 gtatccagct tctatttgag aacctttgta aacatcaaat aacttgtagc tttctactaa
     2101 tccttgacca ttttccttta ttatatcttc tatttgtttt acaaatacat catctttaac
     2161 aataagagct atatctcttg atgtagatgg atattttggt aatggcacat aattctttgt
     2221 tctatcagaa ttatcaaata caaagtcaat atctatttca gcgacataaa ctctttgacc
     2281 tagattgtag ttttctataa catctggatg caattcacct aatgtaccta catatttatt
     2341 attatacact attttagcac atctaccagg gtggaaggta gtattattat cttgaggttc
     2401 aatttcataa cctttaaatc cgacatttac aagtatagtt tctatagttc cttttagtgc
     2461 aaagaagtca acatctttac catacatacc tacacacatt ctattttctt ctttaggtaa
     2521 ttctgaatct tgtgggatga atatatgtcc acactcaaat gcagatactt cttctatttt
     2581 atgagataca ttagttgata aaacatctaa catatttggt attaaagtag ttctcattac
     2641 agaagtttct tctcctaatg ggttaagtaa tttaacaaag tttctcttag cattaccttc
     2701 tggtactctt atcttatcga ctcccttagg gcttacaaat gaatatgtta atatttcatt
     2761 taatcctaca gcagttgaat tatcttttaa agcatccatg aatttttgtt ttgaagtttt
     2821 aattcctgct gtcgtatttc cttctaattg tacagaaggt atattctcaa atccataaat
     2881 tctagctatt tcttcccata catcagcttc ttgttccata tctgttctaa agcttggtac
     2941 atctatttct aatttatcat tagctaccaa attacattta aactctaatg attctaaaat
     3001 tcctacaaac tgctccattg gtacatctac acctaatagg tggttaattc tttgaggatt
     3061 tactaccaat tttttaggtt ctggtttatt tggatataca tctacaacac cttttaaaac
     3121 ttttcctgct cctaacattt caacaagttg tgcagctcta tttgctgcta tctctgcaag
     3181 attagggtct aagtcttttt catttcttga agatgcttct gacctaatac caactttttt
     3241 agctgtcatt cttatgtttt ctggtttgaa attggcactt tcaaaaagta cagtcttcgt
     3301 attagaagtt atttctgagt tagcaccacc cattacacca gctaaaccaa gtgatttttc
     3361 tccatttgtt ataactagca tatctttatc taatgttctc tcaacatcat ctaatgttac
     3421 aagtttctct ccatctttag catttcttac tactattctt ccagtctcta cttgatttat
     3481 atcaaaagca tgaagtggtt gaccaagctc taacattacg aagtttgtta tatcgactat
     3541 gttacttata ggtcttactc ctgcttctgt aagtcttctt tgcatccaat atggagaagg
     3601 ttctattttt acatctgtaa ccattctagc aacatatctt ctacataaat ctggattatc
     3661 tatctcaact ttgaaatcta tctcttcgtc actttctttt acttcgattt caggatattt
     3721 tacttttgtt cctatagttg cagctgcttc tctagctata cccatcatgc atttacaatc
     3781 aggtctgttt gaagttaatt caaaatctat taaagcatct tttaatccta aaacatcttt
     3841 tatatctttt cctaattcat aagaatcttc gtggtctaaa atatatatac cacctctttt
     3901 atactcctca atgtaatgtt catctatacc tagttcagct gctgaacaca tcataccatc
     3961 tgataattca cctctgaaat cagtctgttt gatttcaact cctccaggta acttagaacc
     4021 atttacagct actggaatat aatctccttc tgatatattt gtagctcctg taactatttg
     4081 aacaacttta tctccaatat ctactttagt tacaaccaac ttatcagcat ttggatgttg
     4141 ttttatttct aaaatctttc caaccaatat attttctatt tcttcaccat aataatctat
     4201 tgtttcaact ttagttcctg tcattgtcat tttatcagcg aactctttta catccatgtc
     4261 tatatcaaca tagtctctaa gccattttaa agatactaac atctacatac cctcctaatt
     4321 aaaattgatt taagaatctc atatcatttt cgaataataa tctaatatca tctatttcgt
     4381 atttaagcat tgcaagtctt tcaaccccaa ctccaaatgc aaatccactg taaacttctg
     4441 ggtctattcc acaatttcta agcacatttg gatgaaccat acctgaacct aatatttcta
     4501 tccaaccttc atatttacac attgggcaac ctttaccacc acatttgaaa caagtaacat
     4561 caacctctgc acttggttct gtaaatggga agttgtgagg tctaaactta gttttgatat
     4621 cagaaccaaa caatttttca acgaagatat ccatagttcc tttaaattct gccatagtaa
     4681 catcttttcc aacaacaagc ccttctatct gatggaacat tggtgagtgt gtagcatctg
     4741 gcgagtctga cctaaaacat ctacctggtg caattacttt tattggtaac tcttgacttc
     4801 tcatagttct tacttgaact ggagatgttt gagttctaag taatacccca tcattgatat
     4861 agaatgtatc gctcatatct cttgatggat ggtctttagg agcgtttaat gcgtcaaagt
     4921 tgttttcaac agtctcaact tctggccctt ctgctataga gaatcccatt ccgataaata
     4981 tatctgttac ttcatctata atttgagtta ttggatgctt cttcccaacc tttaaaactt
     5041 ttcctggttg agtaacatct atcacttcct cttttaattt tctttctttt tcaatagcat
     5101 ttatttcttc ttttttagaa tttatgctaa gttcaatgtt ttctcttacc tcattggcaa
     5161 ccttaccaac tactggtctt tcttcagcag ataatttacc catttcttta agtatggcag
     5221 ttatctcacc tttttttcct aagtacttaa ctcttaaact ttctacactt tctatgcttt
     5281 gtgcttcttt tatttcagcc aaagctgctt cacgtaaagc aagtaatttt tcttgcacac
     5341 atatcaccct ttcgtttttt tgtataaaaa aagcccctca atccctgtct agggacgaaa
     5401 ggctatagtt tcgcggtacc accctagtag tttaacaatt taaaaatcat caaaccacct
     5461 ctaacaaact taacgcgttt ttgacgtcaa agcctactgt aaaatttcag ctctgttact
     5521 ccagagggaa cttctcatga cctcttagaa aacactccca gcctaggtgt ttatctcttt
     5581 actaagttta atcaaaatac tttcctcttt cattgcattt acaatattat attgtttatt
     5641 ttagtattat atcatttcca ttcaaattat gtgactattt tt
//
LOCUS       DAMJWO010000143         5626 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.148, whole genome shotgun sequence.
ACCESSION   DAMJWO010000143 DAMJWO010000000
VERSION     DAMJWO010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5626
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.148"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            240..1067
                     /locus_tag="PC366_003528"
     CDS             240..1067
                     /locus_tag="PC366_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HDF2579010.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPLMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGNGTVWLAPTQVMYEKLSFGAMPTNDNMNNKVSKQK"
     gene            2084..2548
                     /locus_tag="PC366_003529"
     CDS             2084..2548
                     /locus_tag="PC366_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2579011.1"
                     /translation="MNLNKVKFTEEHAIEVTNWKYEGKYSIYNLPPWEEIKKKNFSLS
                     KEDKRKNFISFINDNKELIGFINLLDEGSYVFFGIGIKPDYCGMGIGKEIISLGLQEC
                     RNKYSTKPIVLNVRTWNMRAVKCYKSQGFKIVETQVQKTHLGDGEFFVMRYQ"
     gene            complement(2815..3459)
                     /locus_tag="PC366_003530"
     CDS             complement(2815..3459)
                     /locus_tag="PC366_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2579012.1"
                     /translation="MFGQSFQNCLVLIKENFKLSTLTNLICSIILLCMIPLIQGVANL
                     DRISTAICLENYVAIIGIVMLVPVFSLEQSKEIDEIVSSKSLSQVIVQLIRILMSIIG
                     IVVLIIGFVNVLIYLGCNFPVVEYIIGSFASAMFIGSLGMFFSNLFNNTIIGYMISIG
                     YLILNMMTKGKYVGKFFIMSMSQGSFDEKYWLILGSVVLIIASLLIKPIKRKIR"
     gene            complement(3389..4678)
                     /locus_tag="PC366_003531"
     CDS             complement(3389..4678)
                     /locus_tag="PC366_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2579013.1"
                     /translation="MNLFIKECKNILKSMVYYIFIVVLVFFYISQLGSSVSNDVSKNI
                     PNDGNPLVAPQKVENIDEYYSVHNQYPYGQKESMKTEKVIPNATINLIREYQKNTYTT
                     YPTGVVKYIKLDQNKTKTIEKYIEEITGKSISEINLIWKTDESIKIDYSKVSLERFEE
                     IMQRVDDILGGGSAYAFDKLQRFGVVPVTYDEAMKNYNYTIQKDKVSNGYARIFCDYI
                     GIVLSIFPVFVAVFMSLKDKRSRMREIIYSKQVSSCKIVLSRYFALVFIMILPVLILG
                     MKDLLPLIFFAKDKGISIDNLAFIKYTLWWILPTLMIVTAVGMSITILTDTPVAIIVQ
                     LIWWLYSINSTGLKGDYSTMGLMIRHNSVLNGDIIIQNFNQIMINRIVISLGALVLVL
                     LAIFLYEQKRRGNLDVWAKFSKLFSSNKRKLQIKHFN"
     gene            complement(4675..5547)
                     /locus_tag="PC366_003532"
     CDS             complement(4675..5547)
                     /locus_tag="PC366_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2579014.1"
                     /translation="MEMKIAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTT
                     FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL
                     SDIPLRKRRKIIAKLLSKVNLTNYQNVKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP
                     TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEA
                     LAKLAEGKVYSIEVDKKDIENIKSRFIVIGMLTHGGKAILRIISDDKPFETAVNCNPT
                     IEDGYMLIMGGDNI"
BASE COUNT         2043 a          777 c          698 g         2108 t
ORIGIN      
        1 ataattttaa catgcccata aaatataata cccacaaatg ataaataata ctcaaaatat
       61 ctattgaaat aactatacat ccttaaataa cttaacttaa atctaaacat ttcaaaaact
      121 tcttaaaaat atgtaaaaat ttgatgataa agtagcgatt ttttcaaaaa aaatgtaata
      181 tagagttata tcttataata ttttagagat aaattttatc atagttggga gaaatttgta
      241 tggatttaag caaaaaagta aaaattttag aaaatgcatc agatggcaaa agcgaatttg
      301 aaatattaga atttgaaaaa cttgagggag cttctagccc attaatggca atgggattat
      361 attttgctag agaagctggt ttgaaagcta gacaaattaa gataaaatta aataattcat
      421 caataaaaac agaagctggt gcattatact attataaagg aaatatatct tctgaaacta
      481 agattggtgg tgttggaggt ctttttaaaa aaggaatatc aggagcactt actaatgaat
      541 caatgatgaa acctgtatac aaaggtactg gagaagttta tttggaacct tcttttagac
      601 attatttatt tatgagtctt gataatgatt ctataattgt tgataaagga ttattctatt
      661 gttgctctga tacaatagaa gtaaaagcat ttacacaaaa gaacttctca tctgctttac
      721 ttggtggtga aggcttcttc caaatagaat taagtggtac tggtgtaatc gttctggaat
      781 gtgttgtacc tcaaagtgaa attgtagagt atgaattgaa aaatggagaa gaattaaagg
      841 tagatggtaa ctttgcaata gcaagaacat ctggggttaa tttttctgtt acaaaatcag
      901 ataaatcttt aattggttct gctttaaatg gtgaaggttt cttaaataca tttactggta
      961 atggtacagt ttggctagct ccaactcaag taatgtatga aaaactaagt tttggagcaa
     1021 tgcctactaa tgataatatg aataataaag tttctaagca aaaatagttg ttttataaat
     1081 atttattaaa tcattattga ttttataaag tcactataaa ttttattaga ttattattat
     1141 aaaatcagag tgtggaaatg tttatgtgta ttctttaaat aaaaatttcc acattctgta
     1201 aggttattat acttgatata taaaattcaa tttaggaaca tagtctaaca tttataaaca
     1261 tattaaggta atgatttctc ttggtaatta ttctcatatc ttattctttg attatattta
     1321 tcttattcct agcccttatg tcatattata tttcttatct tattatttat aattagcatt
     1381 aacttatcta aaatcttgta tttttttaat agtaaagttt acatctatat taaaaagttt
     1441 acatctatat taatttcata aaacaatcaa ggtagtcaag agattcaact ttatttgatt
     1501 ttaaaaattt aagtgaattt gttcttatac acatcttttt aaaattatat ctgtagaaaa
     1561 tatcatttag agctataatt aaattattaa attttagaaa atttattaaa aaatataagt
     1621 taaattaata tttttaaaga ttctttttta taactactag aatactaatt tagtagttat
     1681 tgtatctcta aagtttaagc atggatagat atacatttga taatttgcct ataatttacc
     1741 tactacttgg agtattggag caaatacaat atattaataa taagttccta aaaccaataa
     1801 attaactaat acacataaag atattgatgt tgattataca actataagaa acagatttaa
     1861 cagaatttaa tcaagctaag aaattacata tatcgtgatg tttttgaatt agaaggtaat
     1921 tcaaaattag tttatagtct tctgtgaatc caataaaaag tacagggtac aagaattgtt
     1981 agtaaaattt ttaaagattt tatggataga tataaatagt tttacttatt ttgtaaaatt
     2041 taaaatacca ttaattacct taaatatttt aataggagga catatgaatt taaataaagt
     2101 taaatttact gaagaacatg ctattgaagt tactaattgg aaatatgaag gtaaatattc
     2161 aatatacaac ctacctccat gggaggaaat taaaaagaag aatttttcac tatcaaaaga
     2221 agataaaaga aaaaatttta taagttttat aaatgacaat aaagaattga taggttttat
     2281 aaacttattg gatgaaggaa gttatgtatt ctttggtatt ggtataaaac cagattattg
     2341 tggaatggga attggcaaag aaataattag cctaggatta caagaatgta gaaataaata
     2401 tagtactaaa ccaattgtat taaatgtaag aacctggaac atgagagctg taaaatgtta
     2461 taagtctcaa ggatttaaaa tagttgagac tcaggtacag aaaacgcatt taggggatgg
     2521 agaatttttt gttatgaggt atcaatagtt tataacacta gtcatattgc taatatgaca
     2581 attaaaatga aaaaatacat gtgtgtatgt catagcaata agtgtctttg aaatataaat
     2641 ttgagagcct ttgataaaat tcggtataca tatatatttt atactacaga tatataaatc
     2701 tatctacata cataaagaga ttgtaagtag gtttgtgtat ataaaaataa atttatattt
     2761 cataaatgta ctttttattt gtattacctt tattttatct aagctctcat tttattacct
     2821 aatcttcctt tttattggtt ttattaagag agatgcaatt atcaacacaa cacttccaag
     2881 tatcagccaa tatttctcat caaaactacc ttgactcata gacattataa aaaattttcc
     2941 aacatacttg cctttagtca tcatatttaa aattaaatat cctatagata tcatgtaacc
     3001 tatgattgta ttattaaata aatttgagaa aaacattcct aaacttccta taaacatagc
     3061 tgatgcgaaa cttccaataa tatactcaac tactggaaaa ttacatccaa gatatattaa
     3121 aacatttaca aaacctatga ttaataccac tatacctata attgacatca gtatcctaat
     3181 taattgtaca ataacttgag ataatgattt tgaagatact atctcatcaa tttcttttga
     3241 ttgctctagc gaaaatacag gtaccaacat tactatccct attattgcaa cataattttc
     3301 taaacatata gctgttgaaa ttctgtctaa attagctact ccttgtatta gaggaatcat
     3361 acatagcaat ataattgaac atattaaatt agttaaagtg cttaatttga agttttcttt
     3421 tattagaact aaacagtttt gaaaactttg cccaaacatc aagattcccc cttctttttt
     3481 gctcatataa gaatatagct aacaaaacaa gcaccaatgc tcccaagctt atcacaattc
     3541 tattaatcat aatttgattg aagttttgta taataatatc cccatttaat acactattat
     3601 gtcttatcat tagccccatt gttgaataat cacctttgag tcctgtagaa tttatactgt
     3661 aaagccacca aattaattgc acaataattg ctactggtgt atctgttaat atagtaatac
     3721 tcattcctac agctgtaact atcataagag ttggtagtat ccaccataat gtatatttta
     3781 taaatgctaa gttatcaata gatatacctt tatctttagc aaagaaaatc aaaggaagta
     3841 aatctttcat acctaaaatt aatacaggca atatcattat aaagacaagt gcaaaatatc
     3901 ttgataaaac tattttgcat gaagatactt gttttgaata aataatctct ctcattcttg
     3961 aacgcttatc tttaagtgac ataaaaactg ccacaaatac tggaaatata cttaaaacta
     4021 tacctatata atcgcaaaaa attcttgcat acccattact aactttatct ttttgtattg
     4081 tatagttgta attcttcata gcttcatcat aggtaactgg aactactcca aatctttgta
     4141 acttgtcaaa agcatatgca gaccctcctc ctaaaatgtc gtctactctt tgcattattt
     4201 cttcaaatct ttcaagagat actttagaat aatctatttt tatactttca tcagttttcc
     4261 aaattaaatt tatttcgcta atacttttac cagttatttc ttctatatat ttttctatgg
     4321 tcttcgtttt attttggtct aattttatat acttaactac ccctgttgga tacgttgtat
     4381 atgtgttttt ttgatattct ctaattaggt ttatagttgc atttggaatg accttttctg
     4441 ttttcataga ttctttttga ccatatggat attgattgtg tacagagtaa tattcgtcaa
     4501 tattctctac tttttgtgga gcaactaatg gatttccatc attaggaata tttttactta
     4561 catcatttga aactgaactt ccaagttgag aaatatagaa aaaaactaaa actacaataa
     4621 aaatataata taccatactc tttaatatat ttttacattc ttttataaat agattcatat
     4681 attatctcct cccattataa gcatatagcc atcttcaata gttggattac aatttactgc
     4741 tgtctcaaaa ggtttatcat ctgatataat cctaagtata gcctttccac catgagtcaa
     4801 cattcctata actataaatc tactttttat attttcaatg tcttttttat ctacttcaat
     4861 actatatact ttcccttcag ctagttttgc taatgcttct gttgagccat tgtatatgac
     4921 ttttccacta tccaatatag ctacgttttc acatgtagct tctatatctc caacaatatg
     4981 tgtagataaa ataacgattc tatcatttgc aatttcgcat agtaaatttc taaatcttat
     5041 acgttcttct gggtcaagac ctgctgtcgg ctcatccact attaaaactc tgggattatg
     5101 aattaatgct tgtgctatcc caagccttct attcatacct ccagataaag attttacttt
     5161 cacattttga taattagtaa ggtttacttt gcttaataac tttgctataa tttttcttct
     5221 ttttcttagt ggtatatccg ataaaactgc taaataatcc attgctttat atactgtcat
     5281 gttaggatac attgaaaaat cttgtggcaa ataaccaacc atatttctaa tttccttagt
     5341 attctcaata ggaactccac acatatgtat tgaaccttct gtttttgata ataaagtggc
     5401 taaaattctc ataaatgtgg tttttcctgc tccatttctt cctaaaagac caaacatacc
     5461 actgtcgatt tcaagattta tattatcaag agcttgtttt ttcccaaatc ttttactaag
     5521 attggatact gctattttca tttccatata taaatacacc cccagaaata attttataga
     5581 attttatttt tataaatttt tactgtattt tcataataaa ttctaa
//
LOCUS       DAMJWO010000144         5424 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.149, whole genome shotgun sequence.
ACCESSION   DAMJWO010000144 DAMJWO010000000
VERSION     DAMJWO010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5424
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.149"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..519
                     /locus_tag="PC366_003533"
     CDS             <1..519
                     /locus_tag="PC366_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HDF2579015.1"
                     /translation="MNKPDGYISATTDKYDPTVLDLIDLSYLAFEPFPVGRLDKDTEG
                     LLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLDDGYKTMPSQL
                     NILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLDESLELGEYRE
                     LTDEEVKLIEER"
     gene            546..1907
                     /gene="rlmD"
                     /locus_tag="PC366_003534"
     CDS             546..1907
                     /gene="rlmD"
                     /locus_tag="PC366_003534"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDF2579016.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEETCKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIMVNIVTS
                     SQEDFDMNEFKDMLLGIDLKAELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKGYGYEIKMVKCMDMFPNTPHCETVVKL
                     IRE"
     gene            2231..2386
                     /locus_tag="PC366_003535"
     CDS             2231..2386
                     /locus_tag="PC366_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579017.1"
                     /translation="MFSKNEILKKLIEEYDVKTTTDIQDMLKDLFTNTIHQIFPLSNF
                     NGLNIIY"
     gene            2430..3464
                     /locus_tag="PC366_003536"
     CDS             2430..3464
                     /locus_tag="PC366_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HDF2579018.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTTTSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKVAKETGYNLGLTGAKSNNTYE
                     KEVLKNAYDTGYSTGYNEYKTKKIEEYKAKGIEDSNKDKEKMTFEENIDSEFIDAYNN
                     AYDEIQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKVKLPKAKES
                     VYNQGYNEEDFSIPYEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGTAAVVAGV
                     VYKNKKRKKI"
     gene            3551..3754
                     /locus_tag="PC366_003537"
     CDS             3551..3754
                     /locus_tag="PC366_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HDF2579019.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     ATLSIPGTGISYTKTSTKKRKPK"
     gene            3925..5085
                     /locus_tag="PC366_003538"
     CDS             3925..5085
                     /locus_tag="PC366_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp27"
                     /protein_id="HDF2579020.1"
                     /translation="MKLSKTLLAIGMSVSLLIASCPTSNALSSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGRVSTVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFATDGLETYAIGGKVSMSDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVIIKQCLNITNNVGDSNTGIVKDTNSNNTNKPSNEPSSNNPGL
                     TDKSTVYVTPNGKSYHLTKNCSTLKRSKTINKVTLKQAKSQGKIDPCNVCVK"
BASE COUNT         2152 a          532 c         1058 g         1682 t
ORIGIN      
        1 atgaataaac ctgatggata tatatcagca actacagata aatatgaccc aacagtatta
       61 gatttaattg atttatcata cttagctttt gaaccatttc ctgttggaag gttagataaa
      121 gacacagagg gattattagt tttaactaat gatggaaagc tttctcatag agttttatct
      181 cctaagaagc atgtgcctaa gacttattat gcaaaaattg atggagtagt tactgaagaa
      241 gatgtagaag cttttttaga aggtgtagtg cttgatgacg gatataaaac tatgccatca
      301 cagttaaata tattaaaaag tgatgatgaa tcagaaatag agcttacaat acatgaaggt
      361 aagtttcacc aagtaaaaag aatgtttgaa agcgtaggca aaaaagtagt atacttaaaa
      421 agattgtcta tgggcaattt aaaattggat gaaagtttag agttaggtga gtatagagag
      481 ttaacagatg aagaagtaaa attgattgaa gaaagataat aaagatacta tagtaaattg
      541 gaggaatgtc tgtgaagaaa aaagatgtta tagaatttga agtagataaa atggaatttg
      601 gtggtacatc tttaagtcaa gttggagata gagttatcca tatgaagggt ggaataagtg
      661 gtcaaaaggt gagagctgga gttaaaaaag ttagaagtaa gaaagctgaa gttaagatga
      721 tagaattatt agagaactca ccacttgaaa ctgaagaaac ttgcaagcac tttagagagt
      781 gtggaggatg tacactattg tctgtgccat atgaaaaaca attagaaata aaagaaaaac
      841 aagttatgga tttattttta aagcaagatt tatttggatt tcagttttta gggatagaag
      901 gaagtccaga aaacaaatat tatagaaata agatggaata tacttttgga gatgaagtaa
      961 aaaatggacc tttgacatta ggtcttcata aaaaaggaaa gcatatagat atacaaactg
     1021 ttgaggagtg tatgttggtt gatgaagact tctcaaagat attagtttct agtgtagagt
     1081 ttttcaatga aaaaaagctt ccttattata gaacaatgaa tcacaaagga tatttgagac
     1141 atcttgtagt tagaaaaggg attcatacta atgagattat ggttaatata gtaacttctt
     1201 ctcaagaaga ttttgatatg aatgagttta aagatatgct tttagggatt gatttaaagg
     1261 ctgagttagt aggtgtactt catactatta atgatggttt agcagatgca gtccaatgtg
     1321 atgagttaag agtattgtat ggaagagatt atatacaaga agaaatttta ggtcttaagt
     1381 ttaagatttc accattttcg tttttccaaa ccaatactaa gggagctgag gttctttata
     1441 gtattgctag ggattttatt ggagattaca atgataaggt tgtatttgac ttgtatagtg
     1501 gtactgggtc tattggacag gttatggctg gtgctgctaa gaaagtgtat ggtattgaga
     1561 tagttgagga agctgttgtt gctgctaatg agaatgctaa gttgaatgga cttactaatt
     1621 gtgagtttat tgctggggat gtggctaagg ttgttaagga tttaaaggac aagcctgatt
     1681 tgattattgt tgaccctcct agaccaggca ttcataagga tgctattagg gatatttgtg
     1741 gatttggtgc taaggagatt gtttatattt cttgtaatcc taagtctttg gttgttgatt
     1801 tggttgattt taaggggtat ggttatgaga ttaagatggt taagtgtatg gatatgttcc
     1861 caaatacgcc acattgtgag actgtagtta aacttattag agaataacag ggtttcagac
     1921 ttttatattg tgtcttaaaa gtagatttgc cacctatttg ccaccataat tatttttggg
     1981 tggcaaattt attctacaat gatttcaaaa atatttacca tctggtttct catgttatta
     2041 gttacatgta aatatgtatc catagttgtt gaagttttag catgtccgag tatatgctgg
     2101 atatctttta tattagtacc attttctaat aacatagtat cagggttttt aaaataaagt
     2161 gtgtattctt ctagagtagt gataattaaa atatcaaata tcactataca aaggaaagtg
     2221 cacccttttt atgtttagca aaaacgaaat attaaaaaaa cttattgaag aatatgatgt
     2281 caaaacaact acagatattc aagatatgct aaaagattta tttacaaata caattcatca
     2341 aatatttcca ttgtcgaatt ttaacggttt aaacataata tattgactga tataataaaa
     2401 tcatagaata ttttaggggg aaatagatta tgtttaagaa aaagttaata gctgttgcaa
     2461 tgagtataac tatgattagt gtagggagct tttcgtatgc tcattcagga agaactgatt
     2521 catcaggagg tcatcgtgat aataaaaata aatctggatt aggaagttat cactatcatt
     2581 gtggtggtta tccagcccat ttacataata atggtggttg tccttatact ggaggaggaa
     2641 gcagttctgg aacaacaact tcggttaata atgaagaaaa gcaaaagagg tctgttggag
     2701 aaaaaggata taatcaaggg tatgaagatg ggtataaagg aaattatagt tcatcaaatt
     2761 atagtggaga ttatagtgat acatatgaat caaagtactc agaaggatat gaaaaaggta
     2821 aggctaaatt agaagaggaa gaaaaggtgg ctaaagagac tggatataat ttagggctta
     2881 caggtgctaa atctaataat acatatgaaa aagaagtttt aaaaaatgct tatgataccg
     2941 gatattcaac tggatacaat gaatataaga ctaaaaagat agaagaatat aaagctaaag
     3001 ggatagagga tagcaataaa gataaagaaa aaatgacatt tgaagaaaac atagattctg
     3061 aatttataga tgcttataat aatgcttatg acgaaataca agaacaatta aaaaatgatt
     3121 acactactca aggatttgag agtgctatca aaggagaaag atttgacaca tcaactatag
     3181 gtaatgttaa atatgctaat tggtttaaag aaggatatga taatggtaag gttaagttac
     3241 ctaaagcaaa agaaagtgta tataatcaag gttacaatga agaagatttt agtataccat
     3301 atgaaatgaa gtctattgaa actaagttaa aaggtgtata tgatgaaggt ttagaaaaaa
     3361 gagaagaaga gaaaagtaga aatgctactt atggggttgg agctggaaca gcagctgtag
     3421 ttgctggagt agtatataaa aataaaaaac gtaaaaagat atagatgcta gatataccaa
     3481 tgatgacaag tgtataacaa atataatttt aagtataaat atttaaaata tagaagggaa
     3541 ggttatatct atgggattta actttaggaa aagcataaat ctaggaggag gactcaaatt
     3601 aaatttaggt aagaagagtg taggtataag tgctggtgtt aaaggtgcta gagtgtcagt
     3661 taattcaaaa ggaagaaaat cagctacatt gagtatacct ggaactggaa tatcatatac
     3721 aaaaactagt acaaagaaac gtaaacctaa ataaatattt gatatactaa gaaatagact
     3781 gttacaaata gtctattttt tagtatatag atttaaaaag tgacaaaatt ttgaaatata
     3841 aactaatttc ataaaggaaa atattctttt atgtagaatt ataatattta agtaatatta
     3901 taaaatttat aggaggattt cattatgaaa ttaagcaaaa cactattggc aatagggatg
     3961 tctgtttcat tattgattgc tagttgtcca acatcaaacg ctcttagttc tattaattca
     4021 ataaaaggta caaataagta tgaaacagca ggtttaatag cagataaaca aaattatgat
     4081 attgcaatac ttattaattc tgaaaatgga ttatctgatg gattgtcagc aagtggattg
     4141 tcaggagcta aaaatgcccc aatattgtta actaagaaag atacaatccc ttcagaaaca
     4201 ttaaaaagat tagaaaaggt aaaagaagta tatctaattg gaggaaaaaa ttcgatagga
     4261 gcatcagttc agaaaatatt aagtgataaa aaaataagca taaatagaat aagtggaact
     4321 gatagaatag atacaagtca taaagttgca aaagaaatag gaagagtaag tacggttaaa
     4381 aaagtaatat taactaatgc ttttaaaggc gaaccagatg ctatgagtgt tgcttctata
     4441 gcagttagag ataaatctcc aatagtatta actgatggaa atactacaag ttttgctaca
     4501 gatggattag aaacttatgc aattggtgga aaagtcagta tgagtgataa gttaataaat
     4561 gaaactaaag caacaagaat aggtggagta gatagatacg atacaaataa acaaataata
     4621 aataaatttt ataatggctc aaaagaattt tacatagcaa gtgggactga tttagtttat
     4681 tctttagttg gttctacaat tgcacaaaaa acacctatag tgttagttgg aaatggaagt
     4741 aataagagta tattaaaaaa tgcaagtaaa ataactgcta ttggaaatat tgatgatgtt
     4801 attataaaac aatgtttaaa tataactaat aatgttgggg attcaaatac aggtattgta
     4861 aaagatacta attcaaataa tacaaacaaa ccaagtaatg agcctagctc taataatcct
     4921 ggattaactg ataaaagtac agtatatgta actcctaatg gaaaatcata tcatctaaca
     4981 aaaaattgtt ctacactaaa aagaagtaaa acaataaata aagtaacatt aaaacaagct
     5041 aagtcacaag gtaaaataga cccttgtaat gtttgtgtaa aataatgtat tagccaaata
     5101 tatattaaaa aagacaatta attaagattg tcttttttat tgaagaaata taaatttata
     5161 ttatgtatta ttaaaaagaa aattattaat tataaaaaat aataataaag acgataagta
     5221 ttaaaatttt atgtttccaa tatttatgat ataattaata tggcaaggaa taaatatttg
     5281 aaaaagctat gagtggtgtt tccatggaag tttcttcact ttcttatgag aggaggtgaa
     5341 aactatggaa aatctaatga tgagtattat aactggtgtt atagccagtt acatttacga
     5401 taaattaaag agccactctg acca
//
LOCUS       DAMJWO010000145         5397 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.150, whole genome shotgun sequence.
ACCESSION   DAMJWO010000145 DAMJWO010000000
VERSION     DAMJWO010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5397
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.150"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            174..1010
                     /locus_tag="PC366_003539"
     CDS             174..1010
                     /locus_tag="PC366_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2579021.1"
                     /translation="MNIKKIFNNNVVVSSLEDGTEIIVTGAGVGFKKKVGDLIDENLI
                     SKKYFVQDDQRDKYNQILNKTSIEYFKISEEIIEKANEVLNTQVNDSIILALTSHIEF
                     AVQREKQGIKLPNLILNETKQLYREEFKFGLWAIDEIEKRIGIKLPEDEAGYIAIHII
                     NGLENSQKDEGINILEFSKQVIQIIEEVHGFKLDVNSLNYTRLITHLKFFVQRILRKE
                     TYNDSDIEDMYKLVNKNYNKPKVCTEEIAALVLDRFEYKISKEEELYLMIHINKITNS
                     GC"
     gene            1363..2940
                     /locus_tag="PC366_003540"
     CDS             1363..2940
                     /locus_tag="PC366_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDF2579022.1"
                     /translation="MKKNKLGLWNFFQMLGKTFMFPIALLSVSGMMLGLGAGFTDPKM
                     IEMVPFLGNEYVNLVLNFMLTIGLFAFNNLGALFAMAIPLGLLKKEKEFGAFSGLVGF
                     IAMHIGTNFYLTRADLLVPAEQMSTNGQAMIMGIQTYNTSVLGGIVAGLIVYAIYDKV
                     SNLKIPESLGFYSGPRLVPIVSLIVMSIVGLLIPIVWPPFFNAFQSLGRWISSAGPLG
                     YFSYAVAERVTIPFGLNHLVTSVFRFTPIGGTAVIDGETYFGTLNMFMAYVENNQIIP
                     LDLAGKMEQGKLMIQYGLAGAALAIYRTAKPENRKALKGLLISGVLTVIIGGISEPIE
                     FLFLFISPALFAFHTFMNGLANMVLPYLGVLMGFTGDLIAFISFGVLRGTATGWPIAV
                     LVAVLYFAIYYFVFKWAIIKFNIKTPGREDKEIKVSEGNGSDFKNLSTYKGQQMISAL
                     GGQSNILSLDNCVTRLRLKLQDVSLINEDAIKEAGGIAVVKLDEHTIQVIIGTQVYSL
                     RKQMDKAMEGHLEACND"
     gene            2933..4117
                     /locus_tag="PC366_003541"
     CDS             2933..4117
                     /locus_tag="PC366_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2579023.1"
                     /translation="MINFDKKVDRLGTYCTQWDYVEDRFGKKDLLPFTISDMDLEFPF
                     EITEVLQERLNHRVLGYSRWKHDDFRNSVTNWYIKRFNCSVDSNWIYYSPSVMYSISK
                     LIEMLSNEGDGILINTPAYNAFYDVITNNNRNIIKSHLVNRNGFYSIDFNDFEKKCKK
                     SKIFILCNPHNPTGRVWSELELVKMIGICKNNDVKIISDDIHMDIVYDNRMTPILNVA
                     KDYLDSVFICTSASKSFNIPALTGSYVIIPNEGIRNKFENITRYRDFVNSPAILAILA
                     TMVCYDDCEYWLDELLKYLKENLKYTIDYIKDNLEPLKLVMPEGCYFAWIDFSELKIS
                     GEKFQKLLMDIGEVAIMSGSVYGEEGEFYLRLNVACSREKLEDGLNRIKKTMDYIAKR
                     TL"
     gene            4135..4734
                     /locus_tag="PC366_003542"
     CDS             4135..4734
                     /locus_tag="PC366_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2579024.1"
                     /translation="MGYLKTMVDVMTTEMNAIRCLIDEAGIEYESIVSEIANCEGKVI
                     FMGVGKSAHIGKKLAATFASTGTPSFFVHATEAVHGDLGMIESKDITILISNSGNSME
                     VVNCIKYIKAIGSKTIAFTSNRNSVLAKECDYALIYPAKDEADHLNLAPTTSSTITLV
                     LGDSIACALSKSSNFGSSDFYKYHPGGSLGEKLKTANNG"
     gene            4758..5228
                     /locus_tag="PC366_003543"
     CDS             4758..5228
                     /locus_tag="PC366_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2579025.1"
                     /translation="MFKMFKKKSIKSPISGKVIELSKIQDGVFSQKIMGEGVAIDSTG
                     DIVYAPINGKIVVVAETKHAFVIELENGMELLIHVGLDTVNLKGEGFEALVSMGEQVK
                     EGTPMLKINRPLIELKGISLITPVTITNHSEYNMNTCNVGNSVEGGKDTVIEFK"
BASE COUNT         2024 a          566 c         1032 g         1775 t
ORIGIN      
        1 atatgataaa atatgacaaa ttaattgatg acaataaaaa atattttgtt attgtagtat
       61 tatagggtaa attgcaaaat atatacgaaa gtaaaatttt aaatattgac attaaattaa
      121 atatactata ctatgtaagt gtgatgagag aattttttta gaggggattt atagtgaata
      181 taaaaaagat atttaataac aatgtagtag taagctccct agaagatggc acagaaataa
      241 ttgtcactgg tgctggagta ggatttaaga aaaaagtagg cgatttgata gatgaaaatt
      301 tgatttctaa gaaatatttt gttcaagacg atcaaaggga caaatacaat caaatactta
      361 ataagacctc tattgaatac tttaaaattt cagaagaaat tatagaaaag gctaatgaag
      421 ttttaaatac tcaagtgaat gattcaataa tattagcctt aactagtcac atagaatttg
      481 ctgtccaaag agaaaaacaa ggtataaaat taccaaactt aatattgaat gagacaaaac
      541 aactttatag ggaagaattt aaatttggat tatgggcaat tgatgaaatt gaaaaaagga
      601 taggaataaa attgcctgaa gatgaagcag gatatattgc tattcacata atcaatggtt
      661 tggaaaattc tcaaaaagat gaaggtatta atatactaga gttttcaaaa caagttattc
      721 agataattga agaagtacat ggatttaaat tggatgtaaa ttcattaaat tatactagac
      781 ttataactca cttaaagttt tttgttcaaa ggattctccg aaaagaaact tacaatgata
      841 gtgatattga agatatgtat aagttagtga ataaaaatta caataaacct aaagtgtgta
      901 ctgaagaaat tgcagcattg gtattagaca gatttgaata taagattagt aaagaagaag
      961 aattatattt aatgattcac ataaataaaa taacaaacag tggttgttag gattgtaact
     1021 gataaagcag gcaaaaccta agtcaatgag cttaactatt agattaagtt ttttgattta
     1081 ggttttttta ttagatacaa tcaaaataca gacagtgact tttaggattg taactggtta
     1141 agcaggcaaa acctaaatca ttgaatttaa ctattaggtt aagttttttg atttaggttt
     1201 ttttattaga tacaatcaaa tacagacagt gacttttagg attgtaactg gttgagcagg
     1261 caaaacctaa atcattaaac ttaattatta aattaagttt tttgatttag gtttttctat
     1321 aaatttgatt atgtttttag ataaaaatag gaggggaaaa ttatgaaaaa aaataagtta
     1381 ggtttatgga acttcttcca aatgttaggg aaaacgttta tgttcccaat agcactactt
     1441 agtgtttctg ggatgatgct aggacttggg gcaggtttta cagaccctaa gatgattgaa
     1501 atggttccat ttctagggaa tgaatatgtt aacttagttt taaacttcat gttaacaata
     1561 ggattatttg catttaacaa cttgggagca ttatttgcaa tggcaattcc actaggatta
     1621 ttaaaaaaag aaaaagagtt tggtgctttt tcaggattag taggatttat agcaatgcat
     1681 ataggtacaa atttttattt aacaagagct gatttgttag taccagcaga acagatgtca
     1741 actaatggtc aagctatgat tatgggtata caaacatata atacaagtgt tttaggtggt
     1801 attgtagcag gattaattgt ttatgcaata tatgataaag ttagtaattt aaagatacca
     1861 gaatcattag gattctacag tggaccaaga ttagttccaa ttgttagttt aatagttatg
     1921 agtatagttg gattattaat acctattgtt tggccaccat ttttcaatgc attccaaagt
     1981 ttaggaagat ggatttcttc agcaggacca ttaggatatt tttcatatgc agtggcagaa
     2041 agagttacaa ttccatttgg actaaatcat cttgtaacat ctgtattccg ttttacacca
     2101 ataggtggaa ctgctgttat tgatggagaa acgtactttg gtacattgaa catgtttatg
     2161 gcatatgtag aaaataatca gattatacct cttgatttag ctggtaaaat ggaacaaggt
     2221 aaattgatga ttcaatatgg attagctggt gctgcattgg ctatctaccg tacagcaaaa
     2281 ccagaaaata gaaaggcact taaaggactt ttaatatcag gagtgttgac agttattata
     2341 ggtggtataa gtgaaccaat agagtttcta ttcttattca tatcaccagc attatttgct
     2401 ttccatacat ttatgaatgg tctagcaaac atggtacttc catacttagg cgtgttgatg
     2461 ggattcacag gagatttaat tgcatttata agttttggtg tgttaagagg aacagctaca
     2521 ggatggccaa tagcagtatt agtagcagtt ttatattttg caatatacta ttttgtattt
     2581 aagtgggcaa ttattaagtt taatataaag accccaggac gtgaggataa agaaataaaa
     2641 gtatctgaag gaaatggttc agatttcaaa aatttgtcta catataaagg acaacaaatg
     2701 atatctgctt taggtggtca atctaatata ttatcactag ataattgtgt aactagattg
     2761 cgtttaaaac tacaagatgt atcattaata aatgaggatg caattaaaga ggctggtggt
     2821 atagcagttg ttaaattgga tgagcataca atacaagtaa ttataggaac tcaagtgtat
     2881 tctttaagaa agcagatgga taaagctatg gaaggtcatt tggaggcatg taatgattaa
     2941 ttttgataaa aaagtagacc gattgggtac atattgtacc cagtgggact atgtagaaga
     3001 tagatttggt aagaaggatt tgcttccttt tacaatttca gatatggatt tagagtttcc
     3061 atttgaaata acagaggtgt tgcaggaaag gttaaatcat agagttttgg gatacagtag
     3121 atggaaacat gatgatttta gaaattcagt tacgaattgg tatattaaaa gatttaattg
     3181 tagcgttgat agtaactgga tatattatag tccaagtgta atgtattcaa ttagcaaact
     3241 tattgagatg ttaagtaatg aaggagatgg aatccttata aatactcctg catacaatgc
     3301 tttttatgat gtgataacaa ataacaatcg taatattata aagtcacatc ttgtaaatag
     3361 gaatggattc tattcaattg attttaatga ttttgagaaa aagtgtaaaa aatctaagat
     3421 atttatttta tgtaatcctc acaatccaac tggtagagta tggagtgagt tagaacttgt
     3481 taagatgata ggaatttgta agaataatga tgtcaagata atatcagatg atatacacat
     3541 ggatattgta tatgacaata gaatgacacc tatcttaaat gttgcaaagg actatttaga
     3601 ttctgtattc atttgtacat cagcgtctaa atctttcaat ataccagcat tgactgggtc
     3661 atatgtgatt ataccaaatg aaggtattag aaataaattt gaaaatatca ctagataccg
     3721 tgattttgta aattcgccag caattctagc aatattagct acaatggtct gttatgatga
     3781 ctgcgaatat tggttagatg aactattaaa ataccttaaa gagaatctta aatatacgat
     3841 tgattatata aaagataatt tagaaccatt gaaattggtc atgccagaag gctgttactt
     3901 tgcttggata gatttttccg aacttaaaat aagtggtgag aaattccaaa aattattgat
     3961 ggatattgga gaagttgcta ttatgtcggg gtctgtatat ggtgaagaag gtgagtttta
     4021 tttaaggtta aatgtggcat gttcaagaga aaaacttgaa gatggtttaa ataggattaa
     4081 aaaaactatg gattatattg caaaaagaac tttatagtag gaagggagat agttatggga
     4141 tatttaaaaa caatggttga tgttatgact actgaaatga atgccataag atgtttaata
     4201 gatgaagcag gaatagaata tgaaagtata gttagtgaaa ttgcaaattg tgaaggcaaa
     4261 gtaattttta tgggtgtagg aaaatctgca catataggta agaaattggc agctacattt
     4321 gctagtactg gtacacctag cttttttgta catgcaacag aggcagtgca tggagattta
     4381 ggaatgattg aaagtaagga tattacaatt ttaatatcaa atagtggaaa ttctatggaa
     4441 gtggtaaact gtataaaata tattaaagca ataggttcta agacaattgc atttacttca
     4501 aacagaaatt cagtactggc aaaagagtgt gattatgctt taatatatcc tgcaaaggat
     4561 gaagcagacc atttaaatct agcaccaaca acatcatcta caattacttt ggttttagga
     4621 gattctattg catgtgcatt atctaagagt agtaattttg gttcttcaga tttttataag
     4681 taccatccag gaggaagttt aggtgagaag ttaaaaacag ctaacaatgg ataaaagcaa
     4741 aaaggagagt agtttttatg ttcaaaatgt ttaaaaaaaa atcaataaaa tcacccatat
     4801 caggaaaagt aatagagtta tctaaaatac aagatggtgt attttctcaa aaaattatgg
     4861 gagagggtgt agctatagat tctacaggag acattgtata tgctccaatc aatggaaaga
     4921 tagtagtagt agcagagact aaacatgcat ttgtaataga attagaaaat gggatggaac
     4981 ttcttattca tgttggttta gatactgtaa atttaaaagg cgaaggtttt gaggcattgg
     5041 tgagtatggg agaacaagtg aaggaaggaa caccaatgtt gaaaattaac cgtcctttga
     5101 ttgaattaaa gggtatatca cttattactc cagttacaat aactaatcat tcagagtaca
     5161 atatgaatac atgtaatgta ggcaatagcg ttgaaggtgg gaaagatact gtaattgagt
     5221 ttaaataaag aattaaaata caaggttaat atttataaat acctataaac ttatgtttta
     5281 taagattgat tgtatggatt tattgtataa aaaagaactc tttaattata aattaaggag
     5341 tttttttatt ttgtaaatat tgtttagatt tatatagaaa aacacttagt aataaat
//
LOCUS       DAMJWO010000146         5347 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.151, whole genome shotgun sequence.
ACCESSION   DAMJWO010000146 DAMJWO010000000
VERSION     DAMJWO010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5347
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.151"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(204..1388)
                     /locus_tag="PC366_003544"
     CDS             complement(204..1388)
                     /locus_tag="PC366_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDF2579026.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMIKLVNAVPVFIDTKKENGFKLTKEELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKI
                     MA"
     gene            1761..4112
                     /locus_tag="PC366_003545"
     CDS             1761..4112
                     /locus_tag="PC366_003545"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HDF2579027.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERFEVQGNKKMKNFPFLMGQGVWKGSDDLVPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            4134..4673
                     /gene="nrdG"
                     /locus_tag="PC366_003546"
     CDS             4134..4673
                     /gene="nrdG"
                     /locus_tag="PC366_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HDF2579028.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAREAKINGLDVWSYTGF
                     TFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKKVFLVEQYMKDDLSIAE"
BASE COUNT         2089 a          593 c          850 g         1815 t
ORIGIN      
        1 ttataataaa tttagaattt aacttatata gtttaatttg ataatttgat gaaaaaaata
       61 aaagacttac tgatttttaa atctataggt cttttatttt ttatctaaca tttaaattaa
      121 gttgttgaat atatcttata ttacttactt tatatattaa ttaccattaa tacattatat
      181 ctaattacta ttcatctaaa ttattatgcc attattttat atacaaattc ttttaatttg
      241 tctaatccag ataaaaaagt attttcactg caagcatagg atatacgaat atatttatcc
      301 ataccaaatg ctatgccagg aacaactgca acattatatt cttctaaaaa ttgattacaa
      361 aattctatag aaaaactatc tttatattca aatttctcag atactttaga aagatctata
      421 aatatataga atgcgccatt tggattcaca tatcctacat tatcaataga gtctagtttt
      481 gatttaatta aatctcttct tgatttatat gttttaacca tattgtctat gtcaattgag
      541 caatctttca aggctccata ggctatgtat tgtgctgtta gacttgggtg agatataaga
      601 tgtccttgta tagaactcat tgctttagca atcgttttat tagatgcagt atatcctaat
      661 cttaatccag tcattgcagc tgacttagaa aaaccattta tagttattgt tatatcttta
      721 gcttcttcgc ttaatgatgc aattgatgta aattcaccag tgtagcatat tttttcatat
      781 atttcatctg ctaaaatata tattttattt tgtatgcata catctactat ttctattaat
      841 tcatcttttg tataaacact accagtagga tttgaaggat tgtttattac aagaattttt
      901 gttttatctg ttatagattt ttcaagttct tcttttgtta acttaaatcc attttctttt
      961 ttagtatcaa taaaaactgg aacagcatta actaacttaa tcatttcagg ataactaacc
     1021 caataaggct ttggtaataa gacttcatct ccttcgtctg ttaaagctag taaagtattt
     1081 gttattgagt tttttgctcc acttgataca actatttcgt ctattgaata gttacagtta
     1141 ttttcttcaa taagtttttt acagatttcc tctctaagta tttttaatcc tggaactaaa
     1201 tcatatttag tgtaatcttt atttaaagaa tcaataccat aagattttgc gttattaggt
     1261 acattaaaat cgggttctcc tatactaaga tttattactt taactccatt actttccatt
     1321 tctttaactt tagaactaat acctattgtg taggatggtg ttataaagtt tagtcttttt
     1381 gataacataa aatgcctcct tttaaattat tatttatatt atacgacaaa tttaaagaat
     1441 ttacataagg aaatttgtag atatatacat taatatatat aatagcctac actttttgcc
     1501 taaaattagt gtaaaaaaaa gagaaaaaaa ttttaacttt caaagttgtt agaaacgcta
     1561 ctgttcaaaa tatccacata gtatttgcaa tgatttgcgc aagtttgact attatgtaca
     1621 aatttggtaa tcttaatata gcaattatta agataatccc tttaacttag ttgaagggga
     1681 tttttttaga cttaacatac tacatatagt ggtattggga ttaataaaat acaatatata
     1741 gtaacaggag gtttttttaa ttggttgaat tcgtaaaaaa aagagatgga agagtaattc
     1801 catttaatga agatagaata acaagagcta tatttttagc agcaacgaat gttgcagaaa
     1861 gagaaggaat agtacctgat tataaattat ctgagcaatt aactcaagaa gtaataaagt
     1921 ttttaaatca taaatactca gaatcagttc caagtgttga agatatacaa gattctgtag
     1981 ttaaggttct tatagaaact ggccatgcaa aaactagtga agaatatata atatacagaa
     2041 ctgaaagaag tagaataaga aattcaaaaa caagattgat gaaggcaata gaggaaatta
     2101 cctttgaaga tgcagaagat gctgatataa aaagagaaaa tgcaaatatt aatggtaata
     2161 cagcaatggg aactatgtta caatatggaa gcactgtatc taaagaattt tgtaaaacac
     2221 atatattaaa accagaacat tcttttgctc atgataatgg agatatacac atacatgata
     2281 tggatttttt aaatatggga acattaactt gttgtcaaat agatgttaaa aaactattca
     2341 atggtggatt ttcaacagga catggctttt taagagagcc acaagatata ataagttatg
     2401 gtgcattagc tgcaattgct atacaaagca atcaaaacga tcaacatgga ggtcaaagta
     2461 taccattttt cgattatgga ttggctgaag gtgtatataa gacatttaag aaattctaca
     2521 taggaaattt agctaaagca ttgaagttat ttaaaggaat tgaaaataat gatgtgataa
     2581 agaacatagt atataataca gagaaagaaa caaatcaaaa agttggtctt aagagagatg
     2641 aattgtatct aaacttagaa aaagagaaat taatacagac ttttgatata gatgatgaac
     2701 ttgtaaataa gatgcaaaac tttgcatttg aagaatcgta tagagaaact gataaaaaaa
     2761 catatcaatc tatggaagca tttatacaca atctaaatac aatgcactct agagcaggtg
     2821 cacaggtacc attttcaagt gtaaacttcg gaacagatac ttctgaagaa ggaagaatgg
     2881 taactaagaa tcttctatta tctcaagaaa gaggtttagg taatggagag acaccaattt
     2941 ttccaatttt aatatttaag gtcaaagaag gcataaattt aaatcctgaa gaccctaatt
     3001 atgatttatt taaattatca tgcagagtat cagctaaaag actatttcct aattttagtt
     3061 ttttagatgc gccttttaat gcaaaatatt ataaaaaagg tgaaccagat acagaggcta
     3121 catatatggg ttgtagaaca agagtactta gtaatgtgtg tggttcagaa acagttagtg
     3181 gtagaggaaa catatctttt actacagtaa atttaccaag attgggtata aaacatggta
     3241 ttataaataa tgaaaaggct aatttagatg gtttctttga agaattagat gagaagataa
     3301 acttaattat agaacaatta ttggagcgct ttgaggttca aggaaataaa aagatgaaga
     3361 attttccatt cttaatgggg caaggtgtat ggaaaggttc tgatgattta gtaccagaag
     3421 atacactaaa agaagtaata aaacaaggaa cattgacaat tggatttata ggtttagcag
     3481 agtgccttat tgctcttata ggtaaacatc atggagaaag taaagaagct caagaattag
     3541 gattaaaaat agtgtcacat atgagacata aaatggatga agcaacggac aaatataaat
     3601 taaatttctc cttaatgggt actccagcag aaggtctttc aggtaggttt actaaaatag
     3661 ataaaaaagt ttatggagaa attaaaggta tcacagataa agaatattat actaattcat
     3721 tccatgtacc agtttattac aatataagtg catatgataa aattgagata gaagctccat
     3781 accatgaatt gactaatgca ggtcatataa catatgtaga gttagatgga gatccatctg
     3841 ataatttaga ggcttttgaa actgttataa aagctatgaa agatttgggt ataggatatg
     3901 gaagtataaa tcatcctgta gatagagacc caatatgcgg tttttcaggt gtaataacaa
     3961 gtaatatatg ccctgtatgt ggaagaaatg aagatgaaag tgacatcaaa ttcgaaagaa
     4021 taagaagaat aacaggatac ttagttggta cagttgatag atttaataat gctaaaaaag
     4081 cagaagtaag agatagagta aaacatagat agttttattt gggggaataa gttatgaaaa
     4141 taagaatgtc atctactata agttatgaca gcatagttga tggaccagga ttaagaatgg
     4201 taatatggac tcaaggatgt attcataatt gtaaagagtg ccataatcct cagacacatg
     4261 atttatgtgg aggattttat atggatacag aagaaattat aaataaagtc aaatcattga
     4321 aattacaaaa aggcattacg ctatcaggag gagaaccatt tttacaacca gaaccattag
     4381 aagaaatagc aagagaagct aaaataaatg ggttagatgt atggtcatat actggattta
     4441 cgtttgaaca actgttagat aaaaaaaata gagcgtattt taaaaattta aatttactaa
     4501 agcaaattga tattttagtg gatggaaaat ttatagctga aaaaaaagat ataagcttaa
     4561 agtttagagg gtcatcaaat caaaggataa ttgatgttca aaaaagtttg aaatataaaa
     4621 aagtgttttt ggttgagcaa tatatgaagg atgatttatc tatagcagaa taaaatataa
     4681 ataaacagga ttaaatatat gcatatattt aatcctgttt attttcatat aatatttcaa
     4741 gtttgtataa tgtaacaatt aaaccaaaag actcattgta tatttgaaat taagtttttt
     4801 atagtttata ggtgttttat gtggattacg aatgatatag tatcgataca ttatttaatc
     4861 gattcttatt ccaagaaaca attaatttat agaaattctt aattgttaca atataaatat
     4921 ctagataagt tataagatac tgataaataa tttataaagt ttattaatct aatattgtgt
     4981 gtgaatgtta agtggtcaag tagtctaaaa aatgaaaaag atttaaaaaa gtgttttaac
     5041 taaacacata agtgttaaat tcatgtataa gtataggtta gatacataag aaataattat
     5101 gtaatatcta tctttgtaaa aaaatattaa attttgtaat ttgtggataa atatgtttat
     5161 aatgtggata atatttaatg taataagtta aagcaatatg aatcaactgt ttataatgtg
     5221 gataatatta taaatgtatg aataattgca gtatttaaaa acaaaaaaag ttaaaaaagt
     5281 tgttgactct aaaagaaaaa gttggtatag taatacttgt cctcaagaaa agggcaaaca
     5341 aataaag
//
LOCUS       DAMJWO010000147         5202 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.152, whole genome shotgun sequence.
ACCESSION   DAMJWO010000147 DAMJWO010000000
VERSION     DAMJWO010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5202
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.152"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(562..2697)
                     /gene="rnr"
                     /locus_tag="PC366_003547"
     CDS             complement(562..2697)
                     /gene="rnr"
                     /locus_tag="PC366_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HDF2579029.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIVSPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLP
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEILAKILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYIYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
     gene            3293..3907
                     /locus_tag="PC366_003548"
     CDS             3293..3907
                     /locus_tag="PC366_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDF2579030.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTSRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     VGNALRDISKKYPDLVKKELDSWDISNKKVEFVYKLASKCILAK"
     gene            3925..4287
                     /locus_tag="PC366_003549"
     CDS             3925..4287
                     /locus_tag="PC366_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2579031.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYKGYPLKVEYSLTPIRGKQILDALAIMQDIGIS
                     FMLDNGMEDILKEKGVLK"
     gene            4393..4890
                     /locus_tag="PC366_003550"
     CDS             4393..4890
                     /locus_tag="PC366_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HDF2579032.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELNENESVTATDFVQGTTSWHGKLGG
                     LDRLEASVYGGMAPPDRPHVYEIHVFALDTILDLEKGFYMNEFFKAIEGHVLDTFTLK
                     GSYSN"
BASE COUNT         1711 a          780 c          615 g         2096 t
ORIGIN      
        1 tgaaattata ttttttaata tctattctta attaggtatt tttaaattat ctgtttacat
       61 taaatatctc ttaattactt atctttcagc tagcttcttc tattaaatgt ttctcaatta
      121 cttatttttc aattagccac ttctattaaa catttcttaa ttacttattt ttcaattagc
      181 cacttctatt aaacatttct taattactta tttttcaatt agccacttct attaagcatt
      241 tcttaattac ttatttttca attagtcact tccattaaac atttcttaat tatttatttt
      301 tcagttggct ttttctatta aatgtttctt aattacttat ctttcagtta gctctttcta
      361 ttaaatattt ctcaattact tatttttcaa ttagctactt tcattaaata tttcttaatt
      421 atttatcttt aagttaacta tttccattag atatttctta attacctatt tttatcattt
      481 attttataga gtattgtgca ctatatattt atacatatca taaatactac aacttgttat
      541 ctcttatttt agctgtttta tctactcctc tattttttca actatctcaa agtcaatttc
      601 tttaaaatct acattaacac tttcaacctt tatcttaaca aggtctccta tcttatatga
      661 cttcttagtt ctttctccta aaacactata agaactctca tcataaatat agtaatcatc
      721 attcatattt gcaagtctta tcaatccttc tatagtatta tctaactcaa caaatattcc
      781 aaatgaagtt acgctagata caacaccctc aaattcttga ccaactttat ccttcatata
      841 aagagcctta tagaaatcat gtacatctct ttcagctaac tctgcctttc tttctttctc
      901 ggatgattga acagatgcat aatccactat agtagtaagc tgttcttgtc tttttccact
      961 tattttatta tttaaagatt cttttattat tctatgaatt tgaaggtcag gatatcttct
     1021 tattggtgaa gtaaagtgac agtagaattt agctgctaat ccaaaatgtc cactacattc
     1081 tggtgagtac ttagcttgtt ttaaagaacg aagcattata gtactgatag ctccttcttc
     1141 ttttttgccc tttattttct ctattatacc ttgtaatgct tttggatgta cttcctcttt
     1201 atcacctttt attatatatc caaatgtaga tataaactta ctcaattctt ccattttttc
     1261 caaagatggt gtctcatgta ttctatacac aaacggtatt cccatccagt aaaaatgttc
     1321 ggcaattgtc tcattactta taagcataaa ttcttctatt atcttattag atattcttct
     1381 ttcatatggc tttatatcta caacttcgcc ttttccattt agaattatct ttgcctctgg
     1441 gaaattgaag tctatagctc ctcttttttc tcttcttgac ataagaatct tagctaaaat
     1501 ttcagcattt ttaaaatctt caacaacatg ttcaaaagtc tttttaagtt tttcatcatc
     1561 cttttctaat atatcagata cttctgtata agtcattcta gcttttgaat ttattacaga
     1621 ttcacatatt tcatgtttaa ccacatttcc tttatggtct atttccataa atatagaaag
     1681 agttaactta tcttcaaatg gatttaagct acatactcca tttgaaagag tttttggcaa
     1741 cattggaatt actttatcta ctaaataaac tgatgtagct ctttttaagg cttccttatc
     1801 aagtttattt ttctctctta cataatgtgt aacatcagct atgtgaactc ctagtttgaa
     1861 gtttccatta ggtaatactt ctattgatat ggcatcatct aagtcttttg cgtcatctcc
     1921 atctatagta aatatgttta aatctcttaa atctcttctt ctttttatct cttcttgagg
     1981 aatctcaaca gctacagctt ctgcttcttg caatactttc tttggaaatt cttctggaag
     2041 accatgttct cttattatag aatctatttc tacgcctctt tcaccttttt gacctagtat
     2101 ctctataatt ttgccttctg gttttctatc ctcttgtggc catactgtaa tttcacatac
     2161 taccttatca ttatctactg ctccactaaa atgtttttta ggtatatata tatctttagt
     2221 aaatttcttg ttgtctggtg ttacaaatcc aaaagtttta cttgattgga aagtacctac
     2281 tattctagtt atttctctct ttattacttt tactattctt ccttctgctc tcttttcttc
     2341 agttgcaggt actactattt ctgccataac tctatcgtta tgcatagcac catttatatt
     2401 gtcacttgag ataaataaat cctgtgtata ttcaacatca gattctacaa atccaaaacc
     2461 ctttttgtgt gatacaaatt ttccaacaaa gtatcccatt tgattgggag atactatttt
     2521 tcctttttta gtaaagcaga tataaccatc ttcttctaat tcatttaaaa aattataaaa
     2581 cattggcatt tctgatgaat gtatatcaaa tatttctgct aattcttctt tttttagagg
     2641 attatatgca ctttcattta ttaatcctag caaactttct ttaagtcctg gtatcatttt
     2701 tccctcctgt tttacttttc attatattat tatttatatt gtcttttata tttcttcaga
     2761 taaaacattt tttacttatc acataatttt ctatattttc ttattattat tacaagttaa
     2821 aattacttat ttatattttt gatttaatgt aagctttgtc atactaactt caaacaaatt
     2881 atgatgtttt ataaattatt tgtaaatatc attataatta cttaagttat tctttatcat
     2941 aattgcttaa attactcttt atctcataat tatacaccat caaataggat tggtaaaata
     3001 ttcatctcat ataagtatta ctatataata atttattcta ttagtatact caaatcatgt
     3061 aaaatttata taactcaatt aattttttaa atacaacttt ataatataaa acttataata
     3121 aaagtaaatt tatatgttaa atgaggttga ttttttatta ttttttattt atgctagtac
     3181 taaagacttg caaacgtttt ttgacaagtc tttattttgt ctaaattaaa caaacttttt
     3241 tacaaataaa tacataaaat ttaaactaat ctatttattg gaggagataa aattggaaga
     3301 agtaattgca aaaattatta ctatagaaaa tggattcaaa gaaattgaaa acattgctaa
     3361 aaaaattgta aaaaataatg actcaaaaaa gtgttattat ctatcaatct acttatatag
     3421 gtcagaatat tatcaagtaa gagaattggc tgtgtttata cttggtttta tatcagtaac
     3481 tatttctgaa gctttgttat ttttaaaaga caatgtgagt aaagatgaaa actggagagt
     3541 acaagaaata ctagctaaat catttgatta ttattgcagt gaagtaggat atgaaaaggc
     3601 acttcctgtt ataaaagaat ggcttaattc tgatagtcca aacataaaaa gggctgtgac
     3661 agaaggtctt agaatttgga ctagtagaga ctattttaaa tctaatcctg acgttgctat
     3721 atcactactt tctagtttaa aagaagatga tagcgaatac ttgagaaagt ctgtaggtaa
     3781 tgctcttaga gatataagta aaaaatatcc agatttagta aaaaaagaat tagattcatg
     3841 ggatatatca aataaaaaag ttgagtttgt atataagctt gcttcaaaat gtatcttggc
     3901 aaagtaaaat ggaggtgaac ttatttgaaa cttcgtgatg agtatacttg cccattagaa
     3961 ctaacacatg atatgataaa aggcaaatgg aaatctatta tattatggag attacgcata
     4021 ggaccaacct ccttatcaaa acttgaaaag gaaatcaatg gtattaatca aaagatgtta
     4081 cttgaacaac ttaaagaatt aattgaattt ggtcttgtag ataaaaagac atataaaggt
     4141 tacccactta aagttgaata ctcacttaca cctattcgag ggaaacaaat attggatgct
     4201 ttggctataa tgcaagatat aggaattagc tttatgttgg ataatggtat ggaagatatt
     4261 cttaaggaaa aaggtgtttt aaaataaata gatacccaca aaaaagtaag taatttacca
     4321 ttattttcaa ctggtatata attaaattat agatatattc tattaattta ttataatagg
     4381 aggtaaatta ttatgaaagt aactagtaca ggtatagtaa atggtgttat agaagataaa
     4441 tacggtaaaa gaggaactca gttcaatgaa ggtggtatgc ctacatattc actacctcta
     4501 aagtttgaag atgctccaaa gaatacagta tcctttgctg tatttttaga agataaagac
     4561 tctgttcctg tatgtgggtt tgcatggata cattggttag ctgtaaatat aacaaaagat
     4621 gagttaaatg aaaatgaaag tgtaacagct actgattttg tacaagggac tactagttgg
     4681 catggcaaac taggaggtct tgacagatta gaggccagtg tatatggtgg aatggctcct
     4741 ccagacagac ctcatgtcta tgaaatacat gtatttgcac ttgatactat ccttgacctt
     4801 gaaaaaggat tctatatgaa tgaatttttc aaagctattg aagggcatgt tttagataca
     4861 tttacactaa aaggaagcta ttctaattaa ttaggtttac tatagctaat cattaattaa
     4921 atgctacatt taattgatga ttagcttaat tgttattaga atattttctg cactttatct
     4981 taatatatat tttagttgac tggtatttta atttctatta gattattatc aatttatata
     5041 aattgatttt agcttaaaac ttacttatct atttcagttt ctattagaat tattattaga
     5101 ctcattaaaa taaaagcatt aatataacta ataatatatg ttaaattcat taactctaca
     5161 taaagtttta taatctaaat gaaatacaat aatctgcata aa
//
LOCUS       DAMJWO010000148         5194 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.153, whole genome shotgun sequence.
ACCESSION   DAMJWO010000148 DAMJWO010000000
VERSION     DAMJWO010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5194
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.153"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            147..1040
                     /locus_tag="PC366_003551"
     CDS             147..1040
                     /locus_tag="PC366_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDF2579033.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYAD
                     LASKNNAQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDIL
                     DELEFSNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIAEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYNNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEV"
     gene            1088..3388
                     /locus_tag="PC366_003552"
     CDS             1088..3388
                     /locus_tag="PC366_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579034.1"
                     /translation="MKKIFSIFISCMVVVTTITGCSSGEVIKNTSPINSVKNLDFSFE
                     VKPEIFEVSVESGGSKEKISEPSKERKVSNFKKNKTEASWTYPDENIDINIKKEDSYL
                     DVNIKSNLEKETSFNWPKVEGESYILPLYEGKFIPSNDKYWKEYLNESTYNVIESFSM
                     QFFAVNKAKYSVIYIIENEFNNVIEFSSKDKINFTFKHEYPSINKNKEYGFKIYLTNK
                     NITDVAKTYKNYIVDKGEFKTLKEKSKENKNIEKLYGAPHIYFGDKSIITINDIEWNK
                     LKENLSDDLTNWMKELLSMKSGNSEFIKVINQIKTQDYIDKYQKNQIVQAFNEVMQMN
                     TFYNEKVFESKDREIKKVLDKGISKLSRVELIEFNKKLLKSKLEESVNDVATWAKYNT
                     TDVINDINKSGIKNAWIGFDDMEEGYISLEMVKRANELGYLVGPYDSYHSIHKPGEEK
                     WSTASFKDKSLYENATIENKKGEKETGFQGEGRKLNPTLSLPSVKERVQSILDEGYEF
                     NSWFIDCDATGEIYDDYSQNHITTQTQDLNARLERMSYIRDHANMVIGSEGGNDFSSS
                     TIAFAHGIETPAFAWVDKDMSKNKGSEYYVGKYYSPTGGVPEIFSKQIPVKERYKKIF
                     IDPIYSLPLFRLVYNDSVISSHQWLWGTLKIKDEVGSRMMKEVLYNTPPMYYIDRTEW
                     EKHKDEIISNNKVWSAFNKKAIKKEMTDFKFISEDRLVQMTEYGEDLKVLVNFSQKDI
                     KYNDEVIKANSLVIYDADSKVIYKPE"
     gene            3622..4113
                     /locus_tag="PC366_003553"
     CDS             3622..4113
                     /locus_tag="PC366_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HDF2579035.1"
                     /translation="MYENNKVIYNFERCEKLENALYLSQFNTYKNFKLTSKKTVINSL
                     DTSTYNMNIHSISLVDTMECISSEDEQMTGKKLILVGDIDTDVTLDYAGNKRNRNSSK
                     KNTFKLKIPFSTFIQMPRKIENKDKINLKYLIQDITSSILDDNLFISVTAIISYENSS
                     KIE"
     gene            4141..5088
                     /locus_tag="PC366_003554"
     CDS             4141..5088
                     /locus_tag="PC366_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579036.1"
                     /translation="MRITKTTFNDVFSNDANGSIIKVEKYVDKKCASVFEILTYTIIV
                     TNTSRYKTGNIFFKDYISKYIEFINNTVKVNGIIKRGLDPQQGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNLDKFPTRISIESNRVYTNVNKIVFKQLNISN
                     TLKAPKNLRDILKVNVNSKIFDVKPMKNLINKGSNLKLCNSIVFGCIEVEIDYSCKNR
                     SNFKTVNKFNDIKKDKYYKNDIQNNNENINDCKKQISFGDNKVKKITKTFGFSCFICS
                     PVGIIYEDMKNINIKIEHTSINELNPEELFVNTSLLLYY"
BASE COUNT         2237 a          470 c          841 g         1646 t
ORIGIN      
        1 agaaaactat atattataac aatagtagtg cctttaatta aatatatttc ataaatcttc
       61 ataaaatctt caaaatttcg taaagaatat gtcacaaaag taaggtatat tatattcagc
      121 agatagtata agggaggaca atatttatga agaataaaaa attcattgtt ataatactga
      181 taatatcaat tttaataggt gtattagtga aggaatattc atctagagag ataaaaaagg
      241 atgatataaa tgtcagtaag tatataaaat atgctgattt agcaagtaaa aataatgcac
      301 aagttaactg gaagtatgta gcttccattg ttgctgtgtt aaataaaaat aacttaaaaa
      361 acgttaagga ttcacagata caagaagtat cagatttatt tgttaagaat ttttctaaaa
      421 ataataaaat aaataagtta agtgatattt tggatgagtt agaatttagt aatagacaaa
      481 aaagattggt tgataattat atagacaatc ttaaggatta tggtataaaa ccagaaagat
      541 tgaagtctga tacaaaatat atgaagttta ttgctgaaat taaaacagaa gcaatacaaa
      601 attataagga ttataaaata cttccatcta taactattgc acaagctata atagaatcta
      661 gctggggcaa gtcaactttg gcaaaacaat ataacaatct atttggtata aaggctgacg
      721 cttattggaa aggtaagtca gtgactttag aaacgaaaga acatttagat acaattatag
      781 atgataaatt tagaatatat gatgataaaa atgaatctat aaaagaccat gcaaaatttt
      841 tagccacaaa taaaaggtat aaaaacaatg gtgtatttga tgcaaaaacg tatatatatc
      901 aagctaaagc attagaaaag gcaggttata gtactgcgaa ggatgaaaat ggcaatagta
      961 tatatgcagc tcgtctaata gaattaattc aacagtataa tcttcaatta atagacagcg
     1021 aaattcaaag tgaagtgtaa cttttatgta acataggagt gatatattta tcgaggaggt
     1081 ggtttttatg aaaaaaatat tctcgatatt tataagttgt atggttgttg taactactat
     1141 tactggatgt agtagtggtg aggtgataaa aaatacatca cctatcaata gtgttaaaaa
     1201 tttggatttt agttttgagg tgaaacctga aatatttgag gtatcagttg aatctggtgg
     1261 ttcaaaagaa aagatatctg aaccctcaaa agaaaggaaa gtatcaaatt ttaaaaagaa
     1321 taagacagag gcatcgtgga cgtatcctga tgaaaatata gacataaata taaaaaaaga
     1381 ggacagctat ttagatgtaa atattaaatc taatttagaa aaagaaacta gttttaattg
     1441 gcccaaagtt gaaggggaaa gttatatact accactttat gagggtaagt ttataccaag
     1501 taatgataag tattggaagg agtatctaaa tgagtcaact tataatgtta tagaatcttt
     1561 ttcaatgcaa ttctttgcag taaacaaggc aaagtattct gtgatttata ttatcgaaaa
     1621 tgaatttaac aatgtaattg aatttagttc taaagacaag attaatttta catttaaaca
     1681 tgaatatcca agtatcaata aaaataagga gtatgggttt aaaatatatt tgactaataa
     1741 gaatattaca gatgtagcaa aaacttataa aaattatata gttgataaag gagaatttaa
     1801 aacattaaaa gaaaaatcta aggaaaataa aaatattgaa aaactttatg gagcaccaca
     1861 tatttatttt ggagataagt ctatcatcac aataaatgat attgaatgga ataaattaaa
     1921 agaaaattta tcagatgatt tgactaattg gatgaaagag cttttaagta tgaagtctgg
     1981 caatagtgaa tttataaaag taattaatca aataaaaact caagattata tagataaata
     2041 tcaaaaaaat caaatagtac aagcatttaa tgaagttatg cagatgaata ctttttataa
     2101 tgaaaaagtt tttgaaagca aagatagaga aataaaaaaa gtattagata aaggtatatc
     2161 taaattaagt agggtagaac ttatagagtt taataagaaa ttattgaaat caaaattgga
     2221 agagagcgtg aatgatgttg ctacatgggc aaaatataat acaactgatg taattaatga
     2281 tattaataag tctggtatta aaaatgcgtg gataggattt gatgatatgg aggaaggtta
     2341 tatatcctta gagatggtta aaagagctaa tgagttaggt tatctcgtag ggccatatga
     2401 ttcataccac tctatacaca aaccagggga agaaaagtgg agtacagcat catttaaaga
     2461 taaatctcta tatgaaaatg ctaccataga aaataaaaaa ggtgaaaaag aaactggatt
     2521 tcaaggagaa ggaagaaaac taaatcctac attgtcttta ccaagtgtaa aagagagagt
     2581 acaaagtata ttggatgaag gatatgaatt taattcttgg tttatagatt gtgatgctac
     2641 aggagaaatc tatgatgatt attctcaaaa tcatataaca acacaaacac aagatttaaa
     2701 tgctagactt gaaagaatgt catatataag agaccatgca aatatggtca taggttcaga
     2761 aggtggaaat gatttttcaa gtagtactat agcatttgca catggtattg agacaccagc
     2821 atttgcttgg gtagataaag atatgagtaa gaataaaggc agtgaatatt atgttggtaa
     2881 atactattct ccaacaggag gagtaccaga aatattttca aagcagatac ctgtaaaaga
     2941 aaggtacaaa aaaatattta tagacccaat ttactctcta cctttattta gattagttta
     3001 taatgattct gtgatatctt cccatcagtg gttatgggga actttgaaga ttaaggatga
     3061 agttggaagt agaatgatga aagaagtatt atataataca ccacctatgt attatataga
     3121 tagaactgaa tgggaaaaac ataaagatga aataatctca aacaataaag tatggtcagc
     3181 gtttaataag aaagctatta aaaaagaaat gacagacttt aaatttattt ctgaggatag
     3241 actagttcaa atgactgaat atggagaaga tttaaaggta ttagttaatt tttctcaaaa
     3301 agacattaag tacaatgatg aagtcataaa agcaaattct ttggtaatat atgatgctga
     3361 tagtaaagtc atatataaac cggaataata gatttaatga aaataaagat tgtttaaatt
     3421 tcaagtaaaa aataatataa tattcattta gtttgtatta aagtagtgac tatattaatc
     3481 tggataatta gtatagtcac tattatttat attctttcct aaaagtaagt agtaactgaa
     3541 tcgtgaataa tcaaaaatgg taatttgaaa tagtttttat gaatagtatt aatatataga
     3601 tatagggaga ttgatgtgat tatgtatgaa aataataagg taatatataa ttttgaaaga
     3661 tgtgaaaagc tagaaaatgc tctttattta tctcaattta atacatataa aaactttaag
     3721 ttaacttcta aaaaaactgt aataaactca ttagatacat ctacttataa tatgaatatt
     3781 catagcataa gtctcgttga tactatggaa tgtatatcgt cagaagatga acaaatgaca
     3841 ggaaagaagt tgattttagt tggcgatata gatactgatg taacattaga ttatgcaggc
     3901 aataaaagaa atagaaattc tagtaaaaaa aatacattta aattaaaaat accctttagt
     3961 acatttatac aaatgcctag aaagatagaa aataaagata aaattaattt aaagtatctt
     4021 atacaagata ttacttcatc tattttagat gataatttat ttattagtgt tactgcaatt
     4081 ataagttatg aaaatagttc caagatagag taatctttaa attatagaaa ggtggatgca
     4141 atgagaataa cgaaaactac ttttaatgat gtattttcaa atgatgcaaa tggaagtatt
     4201 ataaaagtag aaaaatatgt tgataaaaaa tgtgcatctg tatttgagat tttgacctac
     4261 actattattg ttacaaatac aagtaggtac aaaactggaa atatattttt caaagattat
     4321 atttctaaat atatagagtt tataaataat actgtaaaag ttaatggcat tataaaacgt
     4381 ggattagacc cacagcaagg tttttacata gggagaatag atgcaagttg taaaaaaata
     4441 atatctttta agagtgtagt tttaccaaat tctgcacata ggattataaa gaatagtgct
     4501 aatatatact attattataa gtgtaatcta gataaattcc caacaagaat atcaatagaa
     4561 agtaatagag tttatactaa tgtaaataaa attgtattca aacaattgaa tataagtaat
     4621 actttaaaag ctcctaaaaa tctaagagat atattaaaag taaatgtaaa tagtaaaata
     4681 tttgatgtta aacctatgaa aaatcttata aacaaaggta gtaatttgaa attatgtaac
     4741 tcgatagttt ttgggtgtat agaagttgaa atagactata gttgtaaaaa taggagtaat
     4801 tttaaaacag taaataagtt taatgatatt aaaaaagata agtattataa aaatgatata
     4861 caaaataaca atgaaaatat aaacgattgt aaaaagcaaa taagttttgg tgataataag
     4921 gtaaaaaaaa taacaaaaac ttttggattt tcttgtttca tttgttctcc agttggaatt
     4981 atttatgaag atatgaaaaa tataaatata aaaattgaac atacatcaat aaatgaatta
     5041 aatccagaag aattatttgt aaatacatca cttttattgt attattaagt attttaaagc
     5101 taaaacttaa acttattaaa atagcatttg gttaaaggaa aatagatatt gatatattta
     5161 taatatatat aaatgattaa ttaaacaatt ataa
//
LOCUS       DAMJWO010000149         5141 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.154, whole genome shotgun sequence.
ACCESSION   DAMJWO010000149 DAMJWO010000000
VERSION     DAMJWO010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5141
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.154"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            63..1835
                     /locus_tag="PC366_003555"
     CDS             63..1835
                     /locus_tag="PC366_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2579037.1"
                     /translation="MENGKFQFFKGVRNCFNMIYLHDKRYLFISMFMAIFQGIVPSIS
                     LLVSQNIINNMQTFSKSVKEILVLLIMYLIINIIPSIFQSFYGYYRIKFNKNFEKHIE
                     TMMLEKSLTLSLKDFEDDNTYDMINRAQSQKGFNITILSENLISIIRESVSTLSLIVV
                     LSQFQLWLIIVVIVIPVLKSLYSIKLGKEQYDVSVNRTWKERKAWYIDYLLSKGYAYK
                     EIMVFRIGSKLINHYKKLKEDIISQDMNIAKKNFIATLLCTVLDSIVSAGIIGFIIIQ
                     GILKKILIGDATTYIQAVQSIKDNVESIFSLFSSVIQDLFYTDLLFKFLDYNCKEDSI
                     EHIKIFEKIGDINKIELINISYKYNHSSEYSLKNINLTLNKNDPIAILGKNGSGKTTL
                     LKILLGFYDDYEGDILINGKNLKDIEKDEYIRKVSCMFQDYIKYEATLKENVAMGDVY
                     KSNLEEKVKSKLKETKLKPSIYEEDGLETILGTWFGKKQLSMGEWQKVAISRTLMKDA
                     DMYIFDEPDSSLDSEAGNELLSLYKKTFENKIGIFITHHIQHAKKITNNIVVLENGKL
                     LESGRHDELMDKKGVYFNLFCNCK"
     gene            1857..3278
                     /gene="ccpM"
                     /locus_tag="PC366_003556"
     CDS             1857..3278
                     /gene="ccpM"
                     /locus_tag="PC366_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-rich peptide radical SAM maturase CcpM"
                     /protein_id="HDF2579038.1"
                     /translation="MNQKPFIHTFKAGKSYFIYDVNTDKILKVNAAVYNYLNKIEHNL
                     EKESDWNIEIEDEINTLINYGFLKNKRVNKTMHPETKYIKYHIENNLSSIILQVTQNC
                     NLRCDYCIYSGSYSNRVHTNKRMNIDVAKRSIDYLIKNSSQLNEVSVGFYGGEPLLEF
                     DLIKQIVEYVKVVGEGKEIYFNLTTNATLFNEEIIEFFVKNNITTMISLDGGKEIHDK
                     SRKFANTGEGSHDVVLKNVRYIKNKYPEYYKKNITFNTVINSENDYISIDDFISKNET
                     LKDSNFLASTLNNNYSDKEIVSSDEYILGKSYDRFLTLLNKLKFIKDESMSPLSRIER
                     ALLDDFRYEKNIEGRLELPDVWHHGGPCIPGAFRIFVTTDGEFFPCERVSESSKMGMI
                     GNLDSGVDIEKAEKLLNIGKLYEEQCSDCWAYSYCDICIAKIDDTKCNENEIKPHDCD
                     RIRHSTENNMKDYCVLKSLGYQY"
     gene            3307..4377
                     /locus_tag="PC366_003557"
     CDS             3307..4377
                     /locus_tag="PC366_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04066 family peptide maturation system
                     protein"
                     /protein_id="HDF2579039.1"
                     /translation="MEKVLIYPFNYNFFTILNHCNKISDIEINSLVSPSGWGLCNKEY
                     NVNNIITKVTNDFQSELKKNSLVWFVDSKENLDLEKFIIPKLKVALKEGKKILYTRDD
                     LNKISRYISHYEFKKINEWNLEKYEIRDIEGISQINTPIIFICGLYGGLDTFDVNIRI
                     GEELRKRGFSILQFGPKKESYLFKMIPIPEFMFDDSISSKTKIINFNHFIKDKEVEAK
                     PDLIIIEVPGELFPFSRKMVGNFGIRAFEISNAVINDCGILCIPSSIYDREYCEELKY
                     FIKGRHGINIDYFSIEKKVIDTYETEVKQKFSYMSLDENFFVEDIEDYEKTFFIHDNK
                     QLLELVDNIVNQLKEYAKVISI"
     gene            4393..4644
                     /locus_tag="PC366_003558"
     CDS             4393..4644
                     /locus_tag="PC366_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide maturation system acyl carrier-related
                     protein"
                     /protein_id="HDF2579040.1"
                     /translation="MNYTEKELLLENIFFDVTGINFNKNNNLKKELFFSPSLHIQPRE
                     LLLVFCEVIENFNIKIPEEKLLNRQFTSFDNVLKIINMV"
     gene            4695..4898
                     /locus_tag="PC366_003559"
     CDS             4695..4898
                     /locus_tag="PC366_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579041.1"
                     /translation="MSFGKRIEMNNIGVETRGVCTIMCPYTCKMMASSSCNCKNNDYN
                     ARGGSYNTYYNKLIHGQRTPDGM"
BASE COUNT         2088 a          450 c          827 g         1776 t
ORIGIN      
        1 tgttatatta tattaattaa taaaatattt tatttcaatt ttattaagta tggaggtgta
       61 ttgtggaaaa tggtaaattt caatttttta aaggtgtaag aaattgtttt aatatgattt
      121 atctacatga taaaagatat ttatttatct ctatgtttat ggcaattttt caggggattg
      181 ttccatctat ttctttgtta gtaagtcaaa atatcattaa taatatgcaa acattttcga
      241 aaagtgtaaa agaaatatta gttttgttaa ttatgtattt aatcataaat ataattcctt
      301 caatttttca aagtttttat ggatattata gaataaagtt taataaaaat tttgaaaaac
      361 atattgaaac aatgatgtta gagaaatctt taactttgag tttaaaagat tttgaggatg
      421 ataatactta tgacatgata aatagagctc aatctcaaaa aggatttaat attactatac
      481 tatctgaaaa ccttatttca ataataagag aatcagtatc tacactttct cttattgttg
      541 tattatcaca atttcaactt tggctaataa tagttgttat tgttattcct gtattgaaat
      601 cattatattc cattaaatta ggaaaggaac aatatgatgt tagtgtaaac agaacttgga
      661 aagaaagaaa ggcctggtac atagattatt tgttgtcaaa aggttatgct tacaaagaga
      721 ttatggtatt tagaattggt tctaaactta ttaatcatta taaaaaatta aaagaggata
      781 ttatatctca agatatgaat atagctaaaa agaattttat tgctacgcta ttatgtacag
      841 ttttagattc aattgtatct gcaggaatta taggatttat aataattcaa ggtattttaa
      901 agaagatttt aataggagat gcgactacat atatacaagc agttcaatct ataaaggata
      961 atgttgaatc aatattttcg ttatttagtt cagtaataca agatcttttt tatacagatt
     1021 tactgtttaa atttctagat tataactgta aagaagactc aattgaacat ataaaaatat
     1081 ttgaaaaaat aggggatata aataaaatag agttaataaa tatttcatat aaatacaatc
     1141 attcatcaga gtattcttta aaaaatatta atttaacttt aaataaaaat gatcctattg
     1201 ctatactagg aaaaaatggt tcaggtaaaa cgacactttt aaaaatatta ttaggttttt
     1261 atgatgatta tgaaggtgac atcttgataa atggaaaaaa tttaaaggat attgaaaaag
     1321 atgaatacat tagaaaagta agttgtatgt ttcaagatta tattaaatat gaggctacat
     1381 taaaagaaaa tgtcgccatg ggagatgtat ataagagtaa cttggaagaa aaagttaaaa
     1441 gtaaacttaa agaaactaaa ttgaaaccaa gtatttatga ggaagatgga ttagaaacta
     1501 ttttaggaac ctggtttggt aagaagcaac tttctatggg tgaatggcaa aaagtagcaa
     1561 tatctagaac tcttatgaaa gatgctgata tgtacatttt tgatgaacca gattcatctt
     1621 tagattctga agcgggaaat gaactccttt ctttatataa aaaaacattt gaaaataaga
     1681 ttggaatatt tataacgcac catatccaac atgcaaaaaa gataactaac aatattgtag
     1741 ttcttgaaaa tggaaagttg ttagaaagtg gaagacatga tgaacttatg gacaaaaagg
     1801 gtgtttattt taatttattt tgtaactgca aataaatatt aaagggaggt taattaatga
     1861 atcaaaaacc atttatacac acatttaaag ctggaaaatc atattttatt tatgatgtta
     1921 atacggataa gattttaaag gtaaatgctg ctgtttataa ttatctaaat aaaattgagc
     1981 ataatttaga aaaagaaagt gactggaaca tagaaataga agacgaaatt aataccttga
     2041 ttaattatgg atttctaaaa aataaaaggg taaataaaac aatgcaccct gaaactaagt
     2101 atataaaata tcatatagaa aataatctat cctctattat tttacaagta acccaaaatt
     2161 gtaatttacg ttgtgactat tgcatttatt ctggttcata cagcaacaga gttcatacaa
     2221 ataaaagaat gaatatagat gtagcaaaaa gaagtattga ctatttgatt aagaattcta
     2281 gtcaattaaa tgaagttagt gttggctttt atggaggaga acccttactt gagtttgatt
     2341 tgattaagca gatagtagaa tatgtaaaag tagttggaga aggaaaggaa atatacttta
     2401 atctaactac aaatgcaact ttatttaatg aggaaataat agaattcttt gtaaaaaata
     2461 atataacaac tatgattagt ttagatggag gaaaagaaat tcatgataaa agtagaaaat
     2521 ttgcaaatac aggagaagga tctcatgatg ttgtattaaa aaatgtacgt tacataaaaa
     2581 ataaatatcc agaatattat aaaaagaata ttacatttaa tacagtgata aattcagaaa
     2641 atgattacat ttctatagat gattttatat ctaaaaatga gactttaaaa gattcaaact
     2701 ttttagcttc cactcttaat aataactatt ctgataaaga aatagtttca tcagatgaat
     2761 atatattagg taagagttat gatagattct tgactttact caacaaatta aaatttataa
     2821 aagatgagag tatgtcacct ttatcaagaa tagaaagagc cttattagat gattttagat
     2881 atgagaaaaa tattgaaggt agattagagt taccagatgt gtggcatcat ggtggaccat
     2941 gtataccagg ggcttttaga atatttgtaa ctacagatgg agaatttttt ccatgtgaga
     3001 gagtaagtga aagttctaaa atgggtatga ttggaaattt agatagtgga gtagatatag
     3061 aaaaggctga aaaactttta aatataggaa aattatatga agagcaatgt tctgattgtt
     3121 gggcctatag ttattgtgat atatgtatag ctaagattga tgatactaaa tgtaatgaaa
     3181 atgaaataaa accacatgat tgtgacagaa ttagacattc tacagaaaat aatatgaaag
     3241 attactgcgt tttgaaatct ctaggatatc aatattaaat tttctaatga aaggaaagat
     3301 gggattatgg aaaaagtact tatatatcca tttaattata atttttttac tattttaaat
     3361 cattgcaata aaatttcaga tatagaaatt aattcactgg ttagtccttc tggctggggg
     3421 ttatgcaata aggagtataa tgttaataat attattacta aagttacaaa tgattttcaa
     3481 agtgaactta aaaagaattc tttggtatgg tttgttgatt caaaagaaaa tctagactta
     3541 gaaaaattta taattcctaa attaaaagta gctctaaaag aaggtaaaaa gatattatat
     3601 acacgtgatg atcttaataa aatatctagg tatatatctc attatgaatt caaaaagatt
     3661 aatgaatgga atttagaaaa atatgaaata agagatatag agggtatatc acagataaac
     3721 acaccaataa tatttatttg tggtctttat ggagggttag atacttttga tgtaaatata
     3781 aggataggag aagaactaag aaaaaggggg ttttcaatat tacaatttgg tcctaaaaaa
     3841 gagagctatt tatttaaaat gattcctata ccagagttta tgtttgatga ttcgataagt
     3901 agtaagacaa agattattaa ttttaaccat tttataaaag ataaagaggt agaggcaaag
     3961 ccagatttaa taattataga agttccagga gaattattcc ctttctctag aaaaatggtt
     4021 ggtaattttg gaattagagc ttttgaaatt tctaatgcag taataaatga ttgtggtata
     4081 ttatgtattc catcaagtat atatgataga gaatattgtg aagaacttaa atattttatt
     4141 aaaggaagac atggtataaa tatagattat tttagtatag agaaaaaagt tatagataca
     4201 tatgagacag aggtgaagca aaaattttca tatatgtcat tagatgaaaa cttttttgtt
     4261 gaagatatag aagattatga aaaaacattt tttatacatg ataataaaca attactagaa
     4321 ttagtggaca atatagtgaa tcaattaaaa gagtatgcta aagtaatatc tatttagaat
     4381 tggaggttaa ttatgaatta cactgaaaag gaattactac tagagaatat attttttgat
     4441 gtgactggaa ttaattttaa taaaaataac aatttaaaaa aagaattatt tttttcaccg
     4501 tctttacata tacagccaag agaattactt ttagtatttt gcgaggtaat agaaaacttt
     4561 aatataaaaa ttccagagga aaaacttttg aataggcaat ttacgagttt tgataatgtt
     4621 ctaaaaataa tcaatatggt ataggttaat aaaggtataa agtaagtgat cttatagaaa
     4681 aggggaggat atgaatgagt tttggaaaaa gaatagaaat gaataatata ggtgttgaga
     4741 caagaggtgt ttgtactatt atgtgtcctt atacttgtaa gatgatggca tcttcatctt
     4801 gtaactgcaa gaataatgat tataatgcaa gaggaggatc atataataca tattataata
     4861 aattgataca tggtcaaaga actcctgatg gaatgtaaat atttcagtaa taagtatact
     4921 attaaattga tttagcatat ttgattaaat ttatctttct tactttattt ccttttatta
     4981 taaaaatatg cagttgatta taattaagag tgtgatttta taataactgc ataaatagta
     5041 tctgttatat aaatcacctc ttcaattatt atagtggtaa atatagtgat taggggtgat
     5101 ttttacaatt taaaagtata aattaattaa aagttattat a
//
LOCUS       DAMJWO010000150         5117 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.155, whole genome shotgun sequence.
ACCESSION   DAMJWO010000150 DAMJWO010000000
VERSION     DAMJWO010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5117
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.155"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            30..1034
                     /locus_tag="PC366_003560"
     CDS             30..1034
                     /locus_tag="PC366_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2579042.1"
                     /translation="MRFKRILILMLTVAMIAGMLVGCANNPSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNAALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGIKSSSRDKFESGFREGVKFSNSSIKDISVEYADVFKDSK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIDAVRAKNKKVIATNKDQHELAPENVISSI
                     VKDFENPTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVNKNNK
                     "
     gene            1159..2271
                     /locus_tag="PC366_003561"
     CDS             1159..2271
                     /locus_tag="PC366_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2579043.1"
                     /translation="MKIKRILMACFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAKS
                     KQSESKSVPTSAEKDKLNSKSKNEEDDTEDDSYVRKTIGVLLDTENLNNESYNNNVLS
                     ALKRADEDFDVRIKLEKPKTSKSFKESIEKLHKYEPDLIIAVGARFAEPIKEAATKYP
                     KQQFAIVDYTYKVQPANVISVSFQDNVTGYLAGLIAGKMTDTGKVGFIGGVEGSSRDK
                     YESGFRKGLKTSNKDAELLVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDSKRA
                     IQVARENGGKVIAINKDQYDMAPDNVISSIIKDVEQPVYELIKNVAKDGFKGSKVMEF
                     KIKDGELGLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            2694..3455
                     /locus_tag="PC366_003562"
     CDS             2694..3455
                     /locus_tag="PC366_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579044.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTIEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            3458..4276
                     /locus_tag="PC366_003563"
     CDS             3458..4276
                     /locus_tag="PC366_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HDF2579045.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            4456..5058
                     /locus_tag="PC366_003564"
     CDS             4456..5058
                     /locus_tag="PC366_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HDF2579046.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIEPIKIPILNIE
                     IVGLIPKRRAEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPSGIKNMIQDYLGEIIESEVKQSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIAQGLITMFI"
BASE COUNT         2138 a          478 c          921 g         1580 t
ORIGIN      
        1 tatcgtaaat gtatgaggag tgaaatttaa tgcgtttcaa aagaatattg atattgatgt
       61 taactgtagc aatgatagct ggaatgttgg ttgggtgtgc taataaccca agcaataatc
      121 ctagctctag caaagataat aaaagtgata taagcgataa aagtaattca aaaaaatctg
      181 tatcaatgat actagatatt gaaggaacaa ataatgaagc tatgaataat gcagctttat
      241 tagcattaaa caatgctcaa aagaaactta atatagatac aaacaaagtg gaatcagatg
      301 attcctcaac tttttctaat agtatagata ttttatgtaa tgacaattac gatttaatta
      361 tagctgtagg agctagattt gcaaaaccat tggagatggt agccaagaaa tatccaaagc
      421 aacaatttgc aattatagac tatgagtatg acaagcaacc ttctaatata acttcaattt
      481 cttatgaaga taataaatct ggatacctag ctggattaat tgctggaaaa atgactgaaa
      541 gcgataaggt tggttttata ggaggaataa agagttctag tagggataaa tttgaatcag
      601 gttttagaga gggtgttaaa ttttctaata gtagtataaa ggatatttca gttgagtatg
      661 cagatgtttt taaagatagc aaatcagtag aatctatagc taaaaaaatg atggataatg
      721 gagtggatat tattttttct actactgaag atgattcaaa agctgtaata gatgcagtaa
      781 gggcaaaaaa taaaaaagtt atagcaacga ataaagacca acatgagtta gctccagaaa
      841 atgttataag ttctattgta aaagattttg agaatcctac ttataatctg atacaaagtt
      901 ttgtaaaagg aaattataaa ggcggaaaag ttatagaaaa cacagttaag tctggaagta
      961 ctgggcttgc ccaaaatagt tctcaaaata ttcctccaga tgtgttagaa tatgttaata
     1021 agaacaataa ataatctact ataatatcca agaatactta tgactttagt tatgaggtga
     1081 attggatgtt ataatagaca tatatagaaa gacgtatgca gaggtaggca gacctatcta
     1141 aatcagggag tgaattttgt gaaaataaaa aggatattga tggcttgctt tgtagtagtt
     1201 tttacaattt ttatattagc tatatgtaac tttgattttg gatttgataa agtaaataag
     1261 aataattcta atatagatag tgctaaatcg aaacagagtg agtctaaaag tgtaccaact
     1321 tcagcagaaa aggataaatt aaatagtaaa agtaagaatg aagaagatga cacagaagat
     1381 gattcatatg taagaaaaac tattggagta ttgttagata ccgaaaactt aaataacgaa
     1441 tcatataata ataatgtact atcagcctta aaaagggctg atgaagattt tgatgttagg
     1501 ataaaacttg aaaaaccaaa gacttctaaa agttttaaag agagtataga aaaactacat
     1561 aagtatgaac cagatttgat aatagcagtt ggagctagat ttgcagagcc aattaaagaa
     1621 gctgctacta aatatcccaa acagcaattt gcaatagttg actatactta taaagttcag
     1681 ccagctaatg taatttctgt atcatttcaa gataatgtta ctggatattt agcagggctt
     1741 attgcaggta aaatgactga tactgggaaa gtcggtttta taggcggagt tgagggttct
     1801 agtagagata agtatgaatc tggatttaga aaggggctta aaacttcaaa taaagatgct
     1861 gagttactag ttaagtattc aaatatattt gaaaaccctg aatcagctag aactattgca
     1921 aaggaaatga gagattctga tagagatgtt gtattttcag ctacagaaga tgatagtaaa
     1981 agagctattc aggtagcaag agaaaatggt ggtaaagtta tagctattaa taaagaccaa
     2041 tacgatatgg ctccagataa tgtaataagt tcaattataa aagatgtaga acaacctgtc
     2101 tatgaactga taaagaacgt tgcaaaagat ggttttaagg gaagtaaagt aatggaattt
     2161 aaaataaaag atggagaact tggcttgact tcaaagagca gtagaaatat accaccagat
     2221 gttttggaat acataaaaaa agagtataac aaagtgaaag atacatatta attattgatg
     2281 tagaagatta taaaaatata ctgtttaagt ttagattagc aataaaaaga tatatttatt
     2341 aaatttgtgc taactgtaca aaatatattg attaagttta gattggtgat aaaaagatat
     2401 atttattaaa tttagtctaa ctgtacaaaa tatattgatt gagtttagat tagcaataaa
     2461 aagatatatt tattaaattt gtgctaactg tacggaatat actgcttaag tttagattag
     2521 tgataaaaag atatatttat taaatttgaa ccaactgtac aaagctatac taattaagct
     2581 tagattaact atataaaatt ataacaataa gtgtgtgggc agaaaaattc tgctacacac
     2641 tttatttata ttcatataaa aaaattatca aaaaaaagaa aaaggagtaa aaaatggaat
     2701 ttacaagaga accatttata ctagatgacg atttgtgtct agctttggtg gacaaaagaa
     2761 ttagttatct aatggaaaat gaattaaaat taagaaatat agagataata aaaacaatag
     2821 aatgtaaaga attatatgaa agcataaaat atcacccgga tatatgtatt tgtaatttag
     2881 gaaaaggaga tataattgtt gcgccgaatg tatataatca atacaaagag ttattaagta
     2941 gatataaatt taatataatt aagggagaag ctaatttatt aaatagatac ccttatgata
     3001 taccttacaa tattgcgata gttggtgact atgctataca caattttaag tatactgaca
     3061 aagcaatatt agattatatt gaaaataata aacttaaaaa gataaatata gagcagggct
     3121 attctaaatg ctcaatctgt atagtagata gaacgtctat aataacatca gataaaggta
     3181 tttggaaaag tatgaagaat acagaaatag agtgtttatt gatagaaaaa ggtcacataa
     3241 atttatttga gatgaattat ggatttatag gtggatgtac agggttgatt tctaaggata
     3301 aactagcttt ttgtggagat gttaaaaaac atcctgacta tgaacgtata aaaagttttg
     3361 tagaaagtaa aaacaaggag atagttacac ttagctgtga aaatttacta gatataggtt
     3421 ctatagttcc tctcatgaca agaaaggagc gataactttg gttgagaagg ataatatttc
     3481 ttccatgaaa tttttgagga ataataatgt aaacgataga ttaatatata cgaatgacat
     3541 tgtagaagta gtgatagatt ctgcaaagca agaagtgtta aataaaaaaa tacttaatgg
     3601 tactaaagct gaacaaagag ctttaaatat tgatgagata tcaacggaaa taactagtat
     3661 gataataagt ataatgaaag agaaactttt gaaagaatac attctaaaat gctatgggcg
     3721 tacatatcct gaagataaaa ataatatata catatattca ctgaacatat ttgctaaaaa
     3781 agagattttt atgagagaaa cagtatttac tagggtgaga aattatatag aagaaaatga
     3841 ttttataaat gtagaaggtt ttattagatt tagaatgaga gaatttatga aatatatttc
     3901 tgctataggt gatattgcag ttgaggagta tttaataaag aaagaccaag atgaatttat
     3961 aagagtttta aaatacttta tagatactca agaagaaaag attgatttgc ttaaagttca
     4021 tataatggaa gataatacat ttgttttata cgataaaaat ggaaataaga tagacagtat
     4081 agatgatgaa gaaattataa atatggtaat aagagaaaat ttaaattatg aggacttttt
     4141 aataagtacc ttattaactc tatgtcccaa aaaaatagaa atattggatt tgttaaataa
     4201 taattgctca aaggaaatta tagatactgt agaagcaatt tttgaaaata aagttagtat
     4261 aattatggaa aactagaatc taagcatata aaagctagcc atataaaatt aaaaaaattc
     4321 tttttaaatc gacacaaaag acttataatt gtatataaag ctatagtata actagagtta
     4381 ttaagtataa agaatatcta cttgattaat gcaatatagc tggcaaatat acaattgata
     4441 aggagtaatt ttataatgga taatttaatt aggatactga tattagctgt tattggtgga
     4501 tttataggtt atgttacgaa tgtagttgct ataagactga tatttagacc aatagagcct
     4561 attaaaatac ctattttaaa tatagaaata gtaggtctta taccaaagag aagagcagaa
     4621 atagcagcaa atgtaggaga aataattcaa gaagaatttc tttctatgga cgaaatactt
     4681 gcaaatatca ttactgacga agataaggaa gaagttgtaa gatacataaa agcaagggta
     4741 aaaattataa tacatgagaa agtttcattt atcccgagtg gtataaaaaa catgatacaa
     4801 gattatctag gagagataat tgagtctgaa gttaagcaaa gtatagatga attgagtaaa
     4861 aatataataa ataaagcaaa tgaacgtata gatatacaaa aaatggtcga agataagatt
     4921 aatgaactag atttatatga attggaagag ataataataa gaatagctaa gaaagaatta
     4981 aaacatatag agtttttggg gcttgtctta gggtttttaa taggtatagc tcaagggtta
     5041 attactatgt ttatttaaat atatgagaag tagcatttat ttaagtacta attatattta
     5101 cctatttgag tgaatta
//
LOCUS       DAMJWO010000151         5109 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.156, whole genome shotgun sequence.
ACCESSION   DAMJWO010000151 DAMJWO010000000
VERSION     DAMJWO010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5109
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.156"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            95..937
                     /locus_tag="PC366_003565"
     CDS             95..937
                     /locus_tag="PC366_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HDF2579047.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTRRT
                     SNKL"
     gene            952..1416
                     /locus_tag="PC366_003566"
     CDS             952..1416
                     /locus_tag="PC366_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579048.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIITCFGQMIALKTQAQDLLIGSISG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLRLNGML"
     gene            1403..2575
                     /locus_tag="PC366_003567"
     CDS             1403..2575
                     /locus_tag="PC366_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDF2579049.1"
                     /translation="MECFKEVVNMNELKAKIKEEIKLLSEEKKTSFEKVSDYLFSNPE
                     LAFEEYKSQKALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPG
                     MGHACGHNIIGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFN
                     NVDAALILHPSDASMPDDISFAQVNLKFDFTGKASHAAAFPWEGKSALSGVIALFNSV
                     NSMRLHLKDYARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKG
                     AAISTGTNVEIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGN
                     LTHEIPAIQAYIKLKENTATHTDEFAVAAGGEEGKVALIKAIKVLAMCGVDILYSK"
     gene            2619..3554
                     /locus_tag="PC366_003568"
     CDS             2619..3554
                     /locus_tag="PC366_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HDF2579050.1"
                     /translation="MILKQVIEVYDILDKANANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKLKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(4353..4751)
                     /locus_tag="PC366_003569"
     CDS             complement(4353..4751)
                     /locus_tag="PC366_003569"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDF2579051.1"
                     /translation="MKWKELYNNARGKLNPRTISPFIDAGGVAAAILTDSGNVYTGVC
                     IDTACTLGMCAERNAIANMITNGESKITKLVCVMSNGSVGSPCGACREYLMQLDKDSA
                     CIEILVNVETEKTVKLSELLPDWWGSDRFI"
BASE COUNT         1787 a          750 c          969 g         1603 t
ORIGIN      
        1 atatatatta tacattatca atgataggtt atataataaa atcactaaca attatattat
       61 aagaaaatta taaaaattac aaggaggtat agaaatgaaa gaaaaagcag ggattagaaa
      121 tgccataata gcagccttta taatcacaat attggcagaa ttaattggac ctatttcatt
      181 taaagttatg ggaataaatg taactttact tagtatacta tgggctatat tcataggaat
      241 ggctgtttct cctcatttat tagggagagt tataccagcc ttaaaaaagt ttatagggga
      301 taatgaaata aatgtatctc catatttatt atctttgaca ctatatccat taggaataat
      361 gtttggaatt aatgcagggc ctaaagttgg tatattactt caagcaggac cagcactttt
      421 attacaagaa tttggtcata tgggtacaat gttgatagca ttacctgttg gagtagcatt
      481 aggtcttgga agaagtgcat taggtggtac tttttcatta tgtcgtgaca cagcactagg
      541 cattattgga gataagtatg gattaaactc accagaaggt ataggaacac taggaactta
      601 cataagtggt agtatatttg gaacattatt attttcattt ttagcaccag tgggtgtact
      661 tttaggattt catccatatg ctttagcaat ggcatcagga atgggtagtg gttcaatgat
      721 gggagctgca acagcatcat taatgaatac ggttccacaa atgtcagagc agattttagc
      781 atattcagct actagtggat tgattacagc tgttactgga atatatatag aattattctt
      841 atctttacca gtagccaact actattatag caaagtagct ccagttattg aaagatttag
      901 aggaagaaaa acaagaagaa caagtaataa attgtaaagg aggatatata tatggaaaaa
      961 acttttaaga ctattatgga gcagataaaa atagtattgt ttatatatat tattacttgc
     1021 tttggacaaa tgatagcact taagactcag gctcaagatt tgttgattgg aagtatatct
     1081 ggatttttgt tggtgataat tgctattata ataaagaatt ttgttaaaaa acctaattta
     1141 ccaggttttg catgggctac attagttgca ttcgttttat cgcttccaat atctccagtg
     1201 ggggatatca tagcaacaaa tgtagggaaa atcaatttta tgtctacagt aacaccatta
     1261 ttagcttttg caggaatctc tgtaggtaac caattagata tattaaagac tttgagttgg
     1321 aagttagtag ttatatcatt tatagttatg acatctactt actttggttc tgcttttata
     1381 tctcaaacag ttttaagatt aaatggaatg ctttaaggag gtagtaaata tgaatgaatt
     1441 aaaagcaaaa attaaagagg aaataaagtt attatctgaa gagaaaaaga catcatttga
     1501 aaaagtttct gactatttat tttcaaatcc agaattagca tttgaggagt ataagtcaca
     1561 aaaagcatta tgtgatttgt tagaagaaaa tgaatttaat gtaactaaag gtgtaggagg
     1621 attagaaaca tcttttgaag ctgtgtattc aaatggaact aatgggaaaa cagttgcttt
     1681 tctagctgaa tatgatgcac ttccaggaat gggacatgca tgtgggcaca atatcatagg
     1741 gacaagttct gttggtgcag gtatcatatt aaaagaaatc atgaaaaaac ataatataga
     1801 agggactgta aaggtttttg gaacacctgc agaagaaaga gtaggtggaa aaataactat
     1861 gattaaagaa ggtgtattta ataatgtaga tgctgcatta atcttacatc caagtgatgc
     1921 ttcaatgcct gatgatatat catttgctca agttaattta aaatttgatt ttactggtaa
     1981 ggcatcacat gctgctgctt ttccttggga agggaaaagt gccttaagtg gagtaatagc
     2041 actatttaac agtgtaaata gcatgagatt acatcttaaa gattatgcaa gagtacatgg
     2101 aattataact gatggaggta gcatacataa tataattcct gaaaaatcta cagctatatt
     2161 taatgtaaga gccttaagca tagaatattt aaatgagatt tgtgaaatgc ttaaaaattg
     2221 tgctaaagga gctgcaattt ctactggaac taatgtagaa atagttcaat tagatgaaat
     2281 atacaaagag attaagaatg attctgaatt agtgaatata gttagacaaa attttgaagt
     2341 tttgggtgaa gactatgttg aaagagattt aagtcaaggt ataggttcaa ctgatacagg
     2401 aaatttaact catgagatac ctgcaataca agcatatata aaattaaaag aaaatactgc
     2461 aactcataca gatgaatttg ctgttgcagc tggtggtgaa gaaggcaaag tagcacttat
     2521 aaaagcaatt aaggtgctag caatgtgtgg agtagatatt ttgtatagta aataatatat
     2581 aattttaaaa tatattaaga aaggaaatcg gattagacat gatattaaaa caagtaatag
     2641 aggtttatga cattttagat aaagcaaatg ctaatgggga agaagtaaaa acttacttac
     2701 aaggttatgg tgaagtagat gtaactgtaa aagaattgtc ttcaagtaaa ggttcaacag
     2761 atttagtaaa gcttacaatt cctgggaaaa atggaaaatt aaaaggtgga gatgctccta
     2821 ctcttggtat tttaggtaga ttaggaggga ttggagcaag accagaagtt ataggttttg
     2881 tctcagatgg tgatggagca ttggtagcaa ttgcagtggc tgctaaactt ttggatatgc
     2941 aacgaaaagg ggacatatta gatggtgatg ttgtaatttc aactcatatt tgcccagatg
     3001 ctccaactaa agaacactat cctactcctt ttatggattc tccaattgat atgatgacta
     3061 tgaatgaaaa tgaagttgat agtagttgtg atgcaatact ttctatagat actactaaag
     3121 gaaatagagt aatcaatact agaggatttg caatatcgcc aactgttaaa gaaggctaca
     3181 tattaaaaac tagtgataac cttttagata ttatgcagac tgtaacaggg aaatctccat
     3241 ttgtattccc tttgtctatt caagatataa caccatatgg aaacaatctg tatcacttaa
     3301 atagtatttt acaaccagca gtagctacag atgcaccaat agtaggagta gcaattacaa
     3361 cagagatgcc tgttgctgga tgtgctacag gtgcaactaa ttttagtgat ttagattcag
     3421 ctgggagatt tgcaattgaa gttgccaagc tatttggtag aaataagtgt gatttctatg
     3481 ataaagaaga gtgggaaatg cttattaaga gatatggcaa attaaataga tttcaaacat
     3541 ttggtataca gtaattagaa aaatattaag tttatataat ttgtgataca actatttaag
     3601 aagatataaa caattaggaa taaaagtaag aataaagcac ttagttaaaa actttaaaaa
     3661 aaaatattta tttgtttata taaaaaggag gattctggtt attgggattc tcttttttat
     3721 gaatacaaat aatatattgt aattataaaa aaaggagcgt ttcaaagtga tttttttaat
     3781 caccttgaga caactcctta tattttttat ttaaattcta ttttttattg actgtatagc
     3841 tattttcacc atcataaggt ggcatgacct tgaacagcgt ggttttgtaa agttgggcac
     3901 cacaaaacaa aaaatcaaca agcccttgtg tggtctgctg acgtgtttac tatactatac
     3961 tttcccaaaa accgcaagca ctatgggagg ctataaggcg gcgaccattc aggggcgatc
     4021 ccctcgaaac cgggataggg ttcccatgtg ggacataata aagagcgccc cggaggtatc
     4081 aactaccatc cggggcgctc tttattatgt cccgtgggaa ccatgcccac gaagcagggc
     4141 gtacaacgga cagataggtc ctaccctcct gacagactgg aatctcaatc ccatcgaaaa
     4201 caatcataac aatcatggca agattatata cactcctgta aaatattttt gtgtgtacca
     4261 tgaagtactg cttgccacta ttgagaacgg ataaaaggga agtacgtatt ataccaataa
     4321 ggtgaacgaa acaaaatact catttgataa agttaaataa acctgtcgga accccaccaa
     4381 tccggcaaga gctcactcaa tttaacagtt ttttctgttt cgacattaac taaaatctca
     4441 atacaagcac tatccttatc aagttgcatt aaatattcac gacaagcacc acatggtgag
     4501 ccaacactcc cattgctcat cacacaaact aatttagtaa ttttactttc gccatttgtt
     4561 atcatattgg cgatagcatt tctttctgca cacattccca atgtacaggc tgtatcaata
     4621 cacacgccag tataaacatt tccgctgtcg gtaaggattg ctgcggcaac cccaccagca
     4681 tcgataaaag gtgaaattgt gcgtggattt aattttcccc tagcattatt ataaagttcc
     4741 ttccatttca tcaggttgat cctcctgttg tatccatata aataatcttt tatacgcctt
     4801 ttccgcctaa ggcacacaac acattactcg cttttttcat tctaatattc gtgcgtgaaa
     4861 atgtcaaacg gtttacttcg tttcattact tcatactgct gttcataacc ctgtttgttc
     4921 acttgggcac cattcgagca ccaatttacc cgtttcaggg ttgtagcgaa cacagcagaa
     4981 atgctcattt catgggcttt tctggctaga aaaaaaattt tatcgctgcc agatatttac
     5041 tattttttat taagttgctg gagttccacc accatcagga ggagtagtag agccaccacc
     5101 attatttcc
//
LOCUS       DAMJWO010000152         5077 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.157, whole genome shotgun sequence.
ACCESSION   DAMJWO010000152 DAMJWO010000000
VERSION     DAMJWO010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5077
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.157"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(188..673)
                     /locus_tag="PC366_003570"
     CDS             complement(188..673)
                     /locus_tag="PC366_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDF2579052.1"
                     /translation="MISELMLKNFGKSSINFKTKIKLNLREKPDINSLKLKSIPEGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNNSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKVITTIPDGFKVEVCYSVGKWARVNINKNEKRYSGYVYNQYIEEHLS
                     L"
     regulatory      complement(756..849)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(1205..1588)
                     /locus_tag="PC366_003571"
                     /pseudo
     CDS             complement(1205..1588)
                     /locus_tag="PC366_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     regulatory      1815..1912
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            1967..2143
                     /locus_tag="PC366_003572"
     CDS             1967..2143
                     /locus_tag="PC366_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579053.1"
                     /translation="MFGNKMDKCTHVLTAYISGSYDYCNFLDTQLDDFILEYGESVVE
                     SCLHQVMVLVSKYN"
     gene            2369..2569
                     /locus_tag="PC366_003573"
     CDS             2369..2569
                     /locus_tag="PC366_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF2579054.1"
                     /translation="MNNGIVKWFNNEKGFGFISMEGRDDVFAHFSAIQTSGFKSLEEG
                     QQVSFDIVKGARGPQAENITIL"
     gene            complement(2733..3032)
                     /locus_tag="PC366_003574"
     CDS             complement(2733..3032)
                     /locus_tag="PC366_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579055.1"
                     /translation="MGFYINYVVCKVKILFSSFSKIILFYINYVVCKLFITLKAILLK
                     TQIIVTTHSPHILQIDSKEEMIVLDMAESGNVYKKELELGEYGVLGWTNEGLYLH"
     gene            3254..3436
                     /locus_tag="PC366_003575"
     CDS             3254..3436
                     /locus_tag="PC366_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HDF2579056.1"
                     /translation="MFKFYNNATLMFLSGTNIKTISERLGHADIKITMNSYSQFLEEM
                     DREAFENLSKILFIVF"
     gene            3507..4352
                     /locus_tag="PC366_003576"
     CDS             3507..4352
                     /locus_tag="PC366_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579057.1"
                     /translation="MNIIKSITLLLTLLIVILMTGCSPRESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISIENLEEFQNILVSTKRIISYKIGKEKIIKKYKHDGKEYKNVV
                     KLEETFNIKNLLYKKDDSLKVNRYFVVENNKYKLLLYESFKKEFGINSMDLAQLKLND
                     FGLKYFKEVDLILKKAIAINPTDSKLYYAQACNYMNFDGFPGYSDTTYNALDSINNSL
                     KYLDKNDSDYKKNASNIYNLKGVILMFHKRFDEAQQYLNKALYFNKDNEDPKYNLNTI
                     KKHLN"
     gene            complement(4576..4740)
                     /locus_tag="PC366_003577"
     CDS             complement(4576..4740)
                     /locus_tag="PC366_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579058.1"
                     /translation="MFGKPKESVRFLDFNDVAEKFGEKKAVAIFDAIAGKKSKEHIIK
                     DIEKLVKNEV"
BASE COUNT         1886 a          649 c          549 g         1993 t
ORIGIN      
        1 ttggtgtata aagtataagt taaatctact ttcaattaaa tttaccattt ataattactt
       61 tataataaaa ataaattagt taatttattc tctttagttc tgttataatg tttctacaaa
      121 aaagaatccc attaatggga ttcttttttg tgatttatta acatatttaa agctcactag
      181 tatcgtatta taaacttaaa tgctcttcta tgtattgatt atatacatat ccagaatatc
      241 gtttttcatt tttattgata ttaactcttg cccattttcc aacgctataa catacttcaa
      301 ctttaaaacc atcagggatt gtagttataa ctttagattc taatgttcta tcatttctaa
      361 gttctaaact taatccattt gttcttatat ttcctatgta attctttttt ctatttttta
      421 ttgtatcatt actattgttt ttagcattac ttaatctttc taaatattta taaagtaacc
      481 agcctttgtc ataattactc tcaacttctg cccatattcc atctacacat tttaacttaa
      541 caattttacc ttctggtata ctttttaatt tcaaactatt tatgtctggt ttttctctta
      601 aattcaattt aattttagtt ttaaaattga tgctagattt gccaaaattt tttaacatta
      661 attcagatat catcttaagc cctcctcttg ccaaatatta agttattaaa atatataact
      721 ctaaaaatac ttttaacaaa aagaattatt atctttttgg caactggctg acatgacctt
      781 tattacataa agattttagt ccctatagtt ttgcgtcatt agatttatct aatattgcct
      841 atatctgaat aataacataa tttgaacaat taaaaaataa tattacctca aattttatat
      901 tatttaaata taaattaaat ttttaattaa taataatcaa aaaatatctt tatatttatt
      961 caattactgt tctttatagt caatataaaa gacagtaatt tatctatagt gttacttata
     1021 ttttatatat atggctattt ttcaacattt tacaatatat ataacattta tttttttaac
     1081 ttttgtcagt aaaatgtcag caagacactt tatccacaat ttttatataa gttttccaca
     1141 acttatcccc agtattatcc acataaaaaa ggtagctctt atattattag ctacctttta
     1201 tttattaatc ttcatatttc cagcttttta tccaacttcc tatttctatt attttttctt
     1261 cagttatttc ttctccatca tgtaattttg aaattaattc tgataaagga ttgttatgta
     1321 aacctctaaa aactcttttt ccctctattt tgagatattc tctctctttt attaatactg
     1381 tatagtgtac atgcctccca attctctatg atattaaaaa accttttttg gttaatctag
     1441 ctaaaagtat aattgtagtt gtatgcttcc aaccatatgt tttttctatt tcatctgcaa
     1501 catcttttga tattacagtt ttataaccag tattccatat gcatttcata atttttaatt
     1561 ctgtatctgg taatttttta tttagcataa tatattcctt ctttcaattt atgtcacttc
     1621 ttcaaattta tctagcttaa attataatag gagtttttta gaacaaaaac tatagttaat
     1681 ttttaccagg tactctacgt gtttagtctg ttttttaagt gtaaaataat gttcatatct
     1741 ataaatttat ttaactttca aacaatcctg ttgaataata actaattcta ttgtattatt
     1801 ttagttgtag aataaaacta aatcggcaaa actagagaaa tttagtgacg caaagctata
     1861 gggactaaga cttatataaa tatcttatga gttatgtcag ccagttgcca aagagatagt
     1921 gttctttttg tttttatgaa agttttttag ggggataata atttatatgt ttggaaataa
     1981 aatggataaa tgtacacatg tattgactgc ttatattagc ggttcgtatg attattgtaa
     2041 ttttttagat acacaattag atgattttat attagagtac ggagaaagtg tagtagagtc
     2101 ttgtttgcac caagtgatgg tattggtaag taagtataat tagatagaca ttgatttcta
     2161 gagaaccctt tttagtttta tctacattta tattaatata tagcaatgta aaacgcttaa
     2221 atatattttt aatattaaga ataactaaaa tgttgactaa aaaatataat taagtagaca
     2281 tttctattaa tctatgatac aatagtattt gtggtaatac acaattaaat caagtatatc
     2341 ttgatatagg ttaataggag tatttttaat gaataatgga atagtgaaat ggtttaataa
     2401 tgaaaaagga ttcggtttta tatcaatgga aggtagagat gatgtgtttg ctcatttctc
     2461 agctatacaa acttcaggat ttaaatcatt agaagaaggt caacaagtaa gctttgatat
     2521 agttaaaggt gctagaggtc ctcaagcaga aaatataact atattataat atatagattt
     2581 ttcgggaaag actcttttta gagtcttttt ttattgttag tatatgtaag ataatcattg
     2641 gtgaagtaaa taaggtatat tgagtaatgt tcttgatagt ttatatgcta atgaatttca
     2701 aaaaaataag cactcctata aaaagagtgc tcttaatgta aatataagcc ttcattggtc
     2761 cagcctaata ccccgtattc tccaagttct aactcttttt tatatacatt accactttca
     2821 gccatatcta acacaatcat ttcttcttta gaatcaattt gtaaaatatg aggactgtgt
     2881 gttgtgacaa ttatttgtgt ttttaggaga attgctttta atgtaataaa aagtttacat
     2941 acaacatagt taatataaaa caaaattatt tttgagaatg agctaaataa aatcttaact
     3001 ttacatacca catagttgat ataaaacccc aaaataaact tagcatctcc aatgtttaca
     3061 catatacaat gctcttaaaa ttgcagtgaa catgcaatag tgcaattgat aatacttatc
     3121 atatattctc aataccttat atttcaactg ctaaacctca atttgtcaca aatatcgctc
     3181 actgcaaaat ttctatattt ttattatatc atagcatata attaatattt tcaattaatt
     3241 tttacattta attatgttta aattctataa taatgcaact ttaatgtttc tttctggaac
     3301 taatataaaa actatttcag aaagattagg tcatgcagat ataaaaataa ctatgaatag
     3361 ctactctcag tttttagaag agatggacag agaagcattt gaaaatttga gcaaaatact
     3421 atttattgta ttttaaagaa gatgacttat tcaatatttg atgctagaat ataattaata
     3481 aaaatttaat tataggtgat tgtattatga acattattaa aagcataact ttactcttaa
     3541 cattattaat tgtgatatta atgacaggat gttccccaag agaaagtgct agtgaagttg
     3601 caaaaaaata tattgataag atgaactctg gtgactatga aacagcatat agtttattaa
     3661 gtaaagatag taaaaaaaaa attagtatag aaaatcttga agaatttcaa aatattttag
     3721 ttagtacaaa aagaataatt agttataaaa taggtaaaga aaaaatcata aaaaaatata
     3781 aacatgatgg aaaagaatat aaaaatgttg ttaaattaga agaaactttt aatataaaaa
     3841 accttcttta taaaaaagat gattctctaa aagtaaatag atattttgta gttgaaaata
     3901 acaaatacaa gctattattg tatgaaagtt tcaaaaaaga atttggtatt aatagtatgg
     3961 accttgctca acttaagctt aatgattttg gactaaaata ctttaaagaa gttgacctta
     4021 tactaaaaaa agctattgct attaatccta ctgattcaaa gctttattat gcccaagcat
     4081 gtaattatat gaattttgat ggatttcctg gttattcaga tacaacatat aatgctttag
     4141 attcaattaa taattcttta aagtatttag ataaaaatga ttctgactac aaaaaaaatg
     4201 caagtaatat atataactta aaaggagtta ttcttatgtt tcacaaaaga tttgatgaag
     4261 cacaacaata tttaaataaa gccttatact ttaacaaaga taatgaagac ccaaaatata
     4321 atctaaatac aataaaaaaa catctaaact agatatttaa tttttgaatt tataaaatat
     4381 ttttttatgt ataattcagc actgaatcat aatctctact aaactaatta caagtttaaa
     4441 ttataaagac ttatttctat ataaatatta ctctataaca ataagtttct tatttaaatt
     4501 ttaaaatatt atctaaaaat cataaaaaag aaggtataaa gagctaccct caagctcaat
     4561 ataccttata aatatctaaa cttcattttt tactaatttt tctatatctt tgataatatg
     4621 ttctttagat ttttttccag ctatggcatc aaaaattgca acagcctttt tctctccaaa
     4681 cttttctgct acatcattaa agtctaaaaa tctaacactt tcttttggtt taccaaacat
     4741 ataacacctc tcatacattt ttatatattt attataactt ctatagactt atttttcacc
     4801 aataaacgtt agacaaatta gtccctttat ttttttaaac tagctttacc ttcaaaattc
     4861 ttaacaaaaa cagtttattc tactctataa ataaaaatag acaatttaat ttgtaggaaa
     4921 ctgataatag aatacagtaa ataaaacttt gtttaatcta tctgaaaaag ttatctatta
     4981 aaactgctat gaatttataa agaatattct agttcataaa aatacaaata tgtaaatata
     5041 atcaccttaa tattcaattt atttaaaata aaaaatg
//
LOCUS       DAMJWO010000153         5058 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.158, whole genome shotgun sequence.
ACCESSION   DAMJWO010000153 DAMJWO010000000
VERSION     DAMJWO010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5058
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.158"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            41..1924
                     /locus_tag="PC366_003578"
     CDS             41..1924
                     /locus_tag="PC366_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HDF2579059.1"
                     /translation="MFNKNKENITLSNQIKGTIQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIVMSKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQEEKLLFTEKRIIELGNENDEKELCEIGNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDPSINPEGVDKWGAIPTRDNFTGGDLQGV
                     IEHLDYLSDLGINGIYFCPITIGKTNHRYDTVDYMEVDPTLGDKETLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKNWFYIKDMSKIDTPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIKYLLDVGKYWIQEFDIDAWRLDVSNEVDHVFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVSEVIFNLLGSHDTTRILTYANGNIDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNKDIFDFMKKIIRLRKENKELRSISNEWVLADKE
                     NGTIILKKESISIIINNSSKNIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
     gene            2148..2828
                     /gene="pgmB"
                     /locus_tag="PC366_003579"
     CDS             2148..2828
                     /gene="pgmB"
                     /locus_tag="PC366_003579"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDF2579060.1"
                     /translation="MIEAFIFDLDGVITDTAYYHYMAWRKLAHKVGIDIDTKFNESLK
                     GISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGIESLLI
                     DVKSNNIKIGLSSASKNAINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSAKGLN
                     VNPQNCIGIEDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYN
                     EYIVRRII"
     gene            2825..>5058
                     /locus_tag="PC366_003580"
     CDS             2825..>5058
                     /locus_tag="PC366_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_097546124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDF2579061.1"
                     /translation="MKCLFSNVDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGVRIFIDDVELDL
                     AKCKVEDFYRELDMKNGILNRRFIVNINDKKFEVRVTRFLSISVKELAVIKYSIKSLN
                     SNTKIKFVPYLDSNIKNEDSNYEEKFWNGISSSSLEYKGSILSRTKENAFNTPVFTVG
                     SMMYIKTNGDVEAVSHESDYNYCENSITMDVLKNKVASIEKYVSITSTRDYKESELLR
                     KCEDILNIELSKSYDDILNEHTKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     DNAKKLGLKGALYPMVTFDGVECHNEWEITFEEIHRNGSIVYAIYNYTNYTGDYKYIK
                     EKGIDVIIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNINNNWYTNCIAKWCLDY
                     AVENILRLEKECNECIDRNNVTREEVEFWKIISNKMYLPYDEELQIIIQNDNFLDKEF
                     VEVKDLPKENFPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWNETLSFDPKLPKEWKNYSFNINYRDNIINVDVCSDLIKIENLKGK
                     PIKI"
BASE COUNT         2091 a          455 c          954 g         1558 t
ORIGIN      
        1 ttagattata taaattatta taaaggaggg aaattttaaa atgtttaata aaaataaaga
       61 aaatataact ttaagtaatc aaatcaaagg aacaattcaa aatagtttaa caaaagaagc
      121 tatattacat ataccaatga gcaattatgc ctatggttat gatagagaaa cactacatat
      181 aagacttaga actaaaaaaa atgaagcgaa aagagtaatt ttacgaatag gagaccaata
      241 tgtgtgggat aaaggaggtg caggaggagg aaatttaaat gcatctggag ttggttggtc
      301 tggtggaaca aatatagtaa tgagtaaaga agtagaaact gaattatttg actattggat
      361 agctaagtgt aagcctttaa ataaacgctc acgatatggt tttataatag aaggtcaaga
      421 agaaaaactt ttatttacag aaaaaagaat aatagagttg ggaaatgaaa atgatgaaaa
      481 ggaattatgt gaaataggta atttttttgg atatccatat ttaaattata tagatatacc
      541 taaagtgcca aattgggtga aagatactgt ttggtatcag atatttccag atagatttgc
      601 aaatggtgac ccgtctataa acccagaagg agtagataaa tggggagcta ttccaaccag
      661 agataatttt acaggtggag atttacaagg tgtgatagaa cacttagatt atttgagtga
      721 tttgggaata aacggaattt acttttgccc tattacaatt ggaaaaacca atcatagata
      781 tgatacggta gattatatgg aggtagaccc tacattagga gataaagaga ctttaaaaaa
      841 actaatagaa gaagcgcata agagaaatat aaaaataatg ttggatgctg tttttaatca
      901 tataggatat tattctaaac agtggcaaga tgtagttcaa aataaggaaa attctcgata
      961 taaaaactgg ttttatataa aagatatgag taaaattgat actccaatag aacagataga
     1021 tgaaaaaaat ataccttatg aaacctttgg gtgtgaaaaa tatatgccta aacttaatac
     1081 agaaaattca gaagtaataa aatatttatt ggatgtaggc aagtactgga tacaggaatt
     1141 tgatatagat gcgtggagat tagatgtttc aaatgaagta gaccatgttt tttggagaaa
     1201 gtttagagaa gaagtcaaaa aagtaaaacc agacatttat atattgggag aaatttggca
     1261 tggtagttta ccatggctaa tgggtgacca atttgattca gttatgaatt acttgatgtc
     1321 agaagccatg aaaaaattct tttgtacaga tgagataaac gccgaagaat ttaagtatat
     1381 gataaatgat gtaatggtaa gttatccaat acaagttagt gaagttattt ttaatttact
     1441 tggaagtcac gatactacaa gaatattgac ttatgctaat ggaaatattg atagatttaa
     1501 acttgcatat atgtttatgt ttgtacaaac aggatgtcct tgtatatact atggtgatga
     1561 aatcggaatg gaaggagaat taagttcaat atctgaaggt caaagaaaat gtatggaatg
     1621 gaatgaagaa aaatggaata aggatatatt tgattttatg aagaagatta ttagacttcg
     1681 taaagaaaat aaagaactta ggtctatatc aaatgaatgg gtgttagcag ataaggaaaa
     1741 tggaacgatt atattgaaaa aagaatctat ttctataata ataaataatt catctaaaaa
     1801 tataattttg acgttaccag attatttagc aaataaaaaa gtaaaagatt tatatgaaga
     1861 agaaatagtt gatttaaaag aagaactaat gttagagaaa tacaagttca ttattttaaa
     1921 ataatacaaa aagtatttat tttagatttc atgttaaatt attatacagt ttaaacaagt
     1981 ctttataaaa cataaaaaaa tatggtttac aagtgagtga attgaaagta gattttaaat
     2041 taaagactga gttagagtag ataattttat aaataatatc ttaaatacaa gatagaaaat
     2101 aaattgatta ttagtctaaa aatttcttgt agaaagagga aataagaatg attgaagcat
     2161 ttatatttga tttagatggt gtaattacag atactgcata ttatcactat atggcttgga
     2221 gaaaactagc ccataaagtt gggatagata tagacacaaa atttaatgaa tctttaaaag
     2281 gcataagtag aatggagtca ttggacagga tattagaatt tggaaataag aaatattcat
     2341 tttcagaaga agaaaaagtg agaatggctg aagaaaaaaa taattactat gtatcattga
     2401 tagatgagat aacttcaaat gatattttgc caggcataga aagcttgtta attgatgtaa
     2461 aatctaataa tataaagata ggtctatctt ctgcaagtaa gaatgcaata aatgtattaa
     2521 atcatttggg tataagtgac aaatttgatt ttatagctga tgcaggaaaa tgtaaaaaca
     2581 ataaaccaca tccagagata tttcttatgt cagcgaaagg gcttaatgta aatccacaaa
     2641 attgtatagg gatagaggat gcaagtgcag gtatagacgc tataaactca gctaatatgt
     2701 tttctgttgg tgttggaaat tatgaaaact taaaaaaagc aaatttagtt gtagattcaa
     2761 caaatcaatt aaagtttgaa tatatacaag aaaagtataa tgagtatata gttaggagaa
     2821 ttatatgaaa tgtttattta gtaatgtaga tgagtggaag attatacaag ataagattga
     2881 aatcaaagaa aatagattag cagagtccat aatgagtata ggcaatggat atatgggtat
     2941 gagaggaaac tatgaggaaa attatagtgg agatacacac aaggggtctt atatagctgg
     3001 agtatggttt ccagataaaa ctcgtgttgg ttggtggaaa aatgggtatc cagaatactt
     3061 tggtaaaatt cctaattcag tcaactatat aggtgtaaga attttcatag atgatgtaga
     3121 attagattta gcaaaatgta aagtagaaga tttttataga gaattagata tgaaaaatgg
     3181 tattttaaat cgtaggttta ttgtaaatat aaatgataaa aaatttgaag ttagggttac
     3241 taggttttta agtatatctg ttaaggaact tgcagtaatt aaatatagta taaaatcatt
     3301 aaattctaat actaaaataa aatttgtacc atatttagat tcaaatataa aaaatgaaga
     3361 ttcaaactat gaggaaaagt tttggaatgg aatttcttca agttctttag aatataaagg
     3421 tagtattctt tctcgaacaa aggagaatgc atttaataca ccagtattca ctgtgggttc
     3481 aatgatgtat attaagacaa atggtgatgt agaagctgta tctcatgaga gtgattataa
     3541 ttactgtgaa aattcgataa caatggatgt tttaaaaaat aaggttgcaa gtatagaaaa
     3601 atatgtatct ataacttcaa ctagagatta taaggaaagt gagctattaa gaaaatgtga
     3661 agacatttta aatatagaac tatctaaaag ttatgatgat atattaaatg aacatacaaa
     3721 gttatggaat aaaagatggg aaagtgcaga tgtaaaaata aatggagata aaagtagcca
     3781 acaaggtata agatataatt tattccaact attttcaaca tattatggag aagattcgcg
     3841 attaaatata ggtccaaaag gatttactgg tgaaaagtat ggaggagcta cttattggga
     3901 tacagaagca ttttgtgttc cagtatatct aggtgtagca gataaggagg taactagaaa
     3961 tcttttagaa tataggtaca atcagttaga acaggcaaag gataatgcaa aaaaactagg
     4021 gcttaaaggt gctttatatc caatggtaac atttgatgga gtagaatgtc ataatgaatg
     4081 ggagataaca tttgaggaaa tccaccgaaa tggaagtata gtatatgcaa tatataacta
     4141 tacaaattat acaggtgact ataaatatat aaaagaaaaa ggaatagatg taataataga
     4201 aatagctaga ttttgggcaa gtagagttca tttgtctaca aaaaaagatt tgtatatgat
     4261 acatggagta acaggtccaa acgagtatga aaacaatatc aataataatt ggtatactaa
     4321 ttgtatagct aaatggtgtt tagattatgc tgtagaaaat atcttacgat tagagaaaga
     4381 gtgtaatgaa tgtattgaca gaaataatgt gactagggaa gaagttgagt tttggaaaat
     4441 aatatcaaat aaaatgtatc tgccgtatga tgaggaacta caaataataa ttcaaaatga
     4501 taatttttta gataaagaat ttgtagaagt aaaggattta ccaaaagaaa attttcctct
     4561 taatcaaaat tggtcttggg ataagattct taggtcgtgt tttataaaac aagcagatgt
     4621 attacaggga atttactatt ttggaaatag atttactaaa gaagaaaaaa agagaaattt
     4681 tgacttctat gaaaaatata ctgtccatga atcttcttta tcttctagta tttattctat
     4741 tattgcctca gaaatagata acctagaaaa ggcttatgaa ttatactcaa gaacagctag
     4801 gcttgattta gataattaca ataatgatac aaatgatgga ctgcacataa cttcaatgtc
     4861 tggttcatgg ctttccattg tacatggatt tgcaggcatg agaacatgga atgaaactct
     4921 atcttttgac cctaagttgc caaaagagtg gaaaaattat tctttcaata taaattatag
     4981 agataatatt attaatgtag atgtatgtag tgatttaatt aaaatagaaa atttaaaagg
     5041 taaaccaata aaaattat
//
LOCUS       DAMJWO010000154         4873 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.159, whole genome shotgun sequence.
ACCESSION   DAMJWO010000154 DAMJWO010000000
VERSION     DAMJWO010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4873
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.159"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            190..696
                     /locus_tag="PC366_003581"
     CDS             190..696
                     /locus_tag="PC366_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HDF2579062.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTVAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHGNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
     gene            1109..1777
                     /locus_tag="PC366_003582"
     CDS             1109..1777
                     /locus_tag="PC366_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579063.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     NGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKEEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSSKEKYEGLWKDDKMHGIGKYTYRDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGVLYKNDGNKQAGIWENDEQCKSLDFKDLNNNKINNVYQNRLNNN
                     KLKV"
     gene            1936..2442
                     /locus_tag="PC366_003583"
     CDS             1936..2442
                     /locus_tag="PC366_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HDF2579064.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLDLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            2570..3586
                     /locus_tag="PC366_003584"
     CDS             2570..3586
                     /locus_tag="PC366_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HDF2579065.1"
                     /translation="MGYYNDNDNNKIRRKKISNNKDSNKKSKHSYTSANKKNKSPNTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPNDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGASTIDMQVSKNLLTS
                     NDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVSE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQVIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     gene            3940..4644
                     /locus_tag="PC366_003585"
     CDS             3940..4644
                     /locus_tag="PC366_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HDF2579066.1"
                     /translation="MKKFVIEDAFWNLFPSAKIGVIICNDIDNSIKDEDYKKIILKGE
                     EEALKYLEDSEFSNNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENSFPYEGEIIYKDD
                     GGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALNELAKIVQEKLGGN
                     CKISILDIDNKEVSVD"
BASE COUNT         2063 a          422 c          810 g         1578 t
ORIGIN      
        1 caatatattt tatctatatt ttacacttat aaaatatgaa aactacttat tgcgaaagta
       61 attgatttgt tgtattataa tttacatgaa ttatgtagga caatcaaaag tcagtattat
      121 aagagtacat atattcaaat ttttaacaat taatttatat aattaaaaaa tgaagggtag
      181 gatgaagtca tgggttttag agaagtaaaa attgaggaac tacagtttaa tccatttact
      241 aagattggca aagaatggtt acttataaca gctggtgatt cagaaaagtt taacacaatg
      301 actgctagct ggggtggtgt tggagtctat tggggtaaaa atgttgttac aacttacata
      361 agaccacaga gatatacaaa agaatttgta gatagtaatg atacatttac agttgccttc
      421 tttgatgaaa cgtatagaga ggctttaaat atttgtggta ctatttctgg tagagatata
      481 aataaaatag aaaaagcagg acttacacca tattttgtgg atgatacggt agcttttgaa
      541 gaagctaata tgattatagt atgtaaaaag ctatatcatg gtaatatgcc accagaaaac
      601 tttgatgcta aagaaaatga taaaaaatgg tatccagaga aagactatca tactatgtac
      661 atttcagaaa ttataaaagt tcttgtaaaa gaataattat aataaaaaat atatgaaaag
      721 aacttattat aagtaaatga ctgtgctttc ttatctgata tctaagtaga tgctactaac
      781 taaataaata ttaattttaa ataaatacta ttataaaaaa gatgaactat atttactata
      841 gttcatcttt ttatttatat aagcacttat ataagtagag atttatttga ataaaagtat
      901 ttatttgaaa tatttgagca tactttataa gtatttttat gctaactaga aacacttaat
      961 ttatggcatt tgtatttgat ttattttaat gtaaataatt tcaaagttaa ttttattcaa
     1021 tatagtacta taaaagtata aataacattt aataaaaata tatattatat taggtatttt
     1081 aaataaattt tttaaagggt gattttttat ggaaaatata actagttatt ttacaacaat
     1141 actatgtgta tttatatgct tatcatctgt atttatattt actcaactag ctagagtatt
     1201 tattaataag aagaagatta atcaaaaaat taaatcaaga aacggattta ggtatgatag
     1261 agattttatt gaagccagaa gagaagaaat acatataaag gataacaata ataataaaaa
     1321 taagagtaac aataagaaat taaaggaaga aaaagtattt aaatacgata atggtgattt
     1381 atataaaggt gagtttgttg atggaaagaa aaatggattt ggaatatata ttttttcaag
     1441 taaggaaaag tatgaaggat tatggaaaga tgacaagatg catggaatag gaaaatatac
     1501 ttatagagat ggttcaatat atacaggtga atttaaatac ggattaaaaa atggtttggg
     1561 aaaattaaca tatcccaata atgacattta taagggatat tttttagata ataagaaaaa
     1621 tggtaagggt gtattatata aaaatgatgg aaataaacaa gcaggaatat gggaaaatga
     1681 tgaacaatgt aaaagtttag attttaaaga tttaaataat aataaaataa ataatgttta
     1741 tcaaaataga ttaaataaca ataaattaaa agtttaatta ttctaataaa aaaatcttta
     1801 tttatgatgg aatataggat atatctatgt tgtaatttgt aaaatcttcc tatatcatat
     1861 aaaattaagt attgattagt ctattacata aatatagaat ataaatatat ccatttaata
     1921 ataaggagaa gagatatgaa agaatatgta gttgtggatt tagaaactac aggattagat
     1981 ccatataaag gttgtgaaat aatagaaata ggaataacag aaataaaaaa tgaacaaatt
     2041 gtaaaaaact attcaaggtt gataaaacct aaggggataa tttcttcatt tataacagaa
     2101 ttgacacata taagtaatga aatggtagaa aatgaagaac cactagaatt agttttacct
     2161 agatttagaa aatacatagg tgatagaact ataattgcac acaatgcgaa atttgattta
     2221 aaatttttaa attactatct taggatgtta gatttagaac caataaacaa ttatatatgt
     2281 acagtagaat tattaaaaaa atgtaaaagt tataaaggaa aaaacaagaa acttgaaaca
     2341 gcttgtgctt attacaacat agagaatata aatgctcata gagctgacag tgatacatta
     2401 gcaactgcaa aactattttt gaaaataaaa gatgaatatt aattataaat atagagaaaa
     2461 ttagtgaaaa tatcctttat aaaattgacc cttaagctta caattttgtt ctttgattta
     2521 ttttgtagaa caatgtataa tgtaccttat atgaagaagg gagactaaaa tgggttatta
     2581 caatgataat gataataata aaataagacg taaaaaaatt agtaacaaca aagatagtaa
     2641 taaaaaatct aaacattctt atacttcggc aaataaaaaa aataaaagtc ctaatacaag
     2701 ttccagtaaa agaatgagtg aaaaagtaga ttcacagaat cttataaaaa gagatagaga
     2761 tagttttaca agagataatg taagaccttt aaatacagat tacaatcaaa gagaaagaag
     2821 aagagtcgag tataaacaaa gagagaaaaa attaaaaagt aaaaaaagaa aaaaacaaaa
     2881 aaggattaga atagttaggg cattattatc tattatgtta gttgcactaa ttatattttc
     2941 agtggcaggt gcaatattta cagtttcagc tataaaaggg tcaccagaag ttactaaaaa
     3001 gttaattagg tctaaatata taagtagtga ggttgtaagt ataaaacaaa tgccaaatga
     3061 tttaaaacat gcaatagttt ccatagaaga tgagagattt tataagcata aaggagtaga
     3121 tgttatttct ctagttaggt cagtattaaa caatgtgttt acagatacaa cacaaggtgc
     3181 aagtactata gatatgcaag tttcaaaaaa cctgcttact agtaatgata aaactatgaa
     3241 gcggaaaata agggatatgt ataatgctaa gcagatgaat aagattatga ctaaggatga
     3301 aattcttgag gcatatttaa ataatatgta tctaggtaaa aatgcatatg gagctgcaaa
     3361 gggagctgaa gtctactttg gtaaaaaagt tagtgaatta aatttagctg agtgtgctat
     3421 gttagctggt atgacaaata atcctgcaag gtatattgac catggagagg ctaagaagag
     3481 acaagtgatt gtactgtata agatgcatca gcttggttat ataactgata aggagtatag
     3541 aatagcaaaa gctgatgaca ctccatttaa atcagaaatt gattaaaatt gtaagaatat
     3601 agtattttca atagtttaaa caaacaaaaa tgtaataaaa aaggtgattt gccacccatt
     3661 tgccaccata attataatct aatggcaaat tgttttaatg tacaaactag ataatagaat
     3721 attgttttaa atgctatatt atgctaaaat ttaattgtat tttgtaaatt aaaaaactta
     3781 taatttagtt ttctagggtt ccgcatttta taatggtcag gtccaagaga aaacgcgcaa
     3841 ttgttgtgta cacggaagga taaaagcctg ggagatattt aataatattt ctataggctt
     3901 ttttattttt acatatttta aatttgagga ggttttctaa tgaaaaaatt tgttattgag
     3961 gatgcatttt ggaatctatt tcctagtgca aaaattggag ttattatttg taatgatata
     4021 gataactcta taaaagatga agactataag aaaataattt tgaagggaga agaagaagca
     4081 ttaaaatact tggaggactc agaatttagc aacaaccaag tgattaaagt atggagagag
     4141 gcatttaaaa aatttaaaac gaaaaaagga gcaaggtctt ctattgaagc attattaaaa
     4201 agagttcata atggaaataa tataggaact attaaccctt tagtggatat ctacaatttt
     4261 atctcattaa aatatgcatt accttgtgga ggggaggata tagataaatt tataggagat
     4321 attaggctaa ctagagcaat tggtaatgag gagtttatcc cactagggac agatgaaaat
     4381 tcatttccat atgaaggaga aataatttat aaagatgatg gtggagcaat ttgtagatgt
     4441 tggaattggc gtgaagcagt gagaacaatg cttactgaag atactaacaa tgccttttta
     4501 tgcattgaat tagtagatga aagtagattt aaagaatttg aaaatgcttt aaatgaatta
     4561 gctaaaatag ttcaagaaaa attgggtggg aattgtaaaa tttcaatttt agatattgat
     4621 aataaagagg tatcagtgga ttaatctgga gatgctgttg taatggacta ttctagttat
     4681 aaagatactt atatttaggg taataagttc tattttagat gtaacgatta tcaaaggata
     4741 taatatagaa aataaaaatg tagaatataa aaagccttta aaataagaaa aaaatgtatt
     4801 ttaaaggctt ttattatact cttttttatt tgcataatta acaataaaaa tatattgtta
     4861 attataatat ttt
//
LOCUS       DAMJWO010000155         4823 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.160, whole genome shotgun sequence.
ACCESSION   DAMJWO010000155 DAMJWO010000000
VERSION     DAMJWO010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4823
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.160"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            141..802
                     /locus_tag="PC366_003586"
                     /pseudo
     CDS             141..802
                     /locus_tag="PC366_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            complement(1021..2058)
                     /locus_tag="PC366_003587"
     CDS             complement(1021..2058)
                     /locus_tag="PC366_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HDF2579067.1"
                     /translation="MNKKLIKAKIFIWSILAISLSIVFISLLIGTIISHSFNFPFNTL
                     NPKYNYDNYIVAKNESFSDKINDINVDWISGEVRIKRSDSNKIKLIQKIPSNFSKKKL
                     AKIMVDGNSLSIYDNSTKKFFIGINLPKPTILELYLPNKLYDKITLYTTSADIYSTYI
                     RSNTVEANTISGAIGLSGNINKINLDTTSGHIDITKLNSKNATLKSTSGEIQLSGKID
                     VLNLETTNGNINLKDIYNKNLTCSSVSGKMNLSGVFSDIKAESTSSNIKINSSKMLSS
                     LYCETTSANVDLSIPDNPGFTLNFDKVSGVLDSDFELNRHSDLYTYKNGITNLYLSTT
                     NGNLTIIKNNH"
     gene            complement(2051..2737)
                     /locus_tag="PC366_003588"
     CDS             complement(2051..2737)
                     /locus_tag="PC366_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579068.1"
                     /translation="MLDKIRTYIDSSFTGVNETKKVKELKDELFENLKEKYNDQIQDG
                     KTEQEAYNSVISGIGDLSELIESVKEPYSLPSELIEEKKKRALRASIAVALFIISPFL
                     FVVSVVSFGIEPTIAILLMLILIALGVGLLVYNQMTRTNYALYNDNLSNKFKEFEDFE
                     ENYNHINPVYKSFMNAYWIIVVSIYLITSILFNIWSFSWILFIIGAAGVNIVKGIIQL
                     KGYKEEDKYE"
     gene            complement(2749..3069)
                     /locus_tag="PC366_003589"
     CDS             complement(2749..3069)
                     /locus_tag="PC366_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2579069.1"
                     /translation="MIIASDMIRGHTETIILKHLLEKDSYGYEINKSILEKTKGLYEL
                     KEATLYTAFRRLEQSGAITSYWGDEVTGARRKYYSITNIGKEKYIKSREEWNNTKALI
                     DILI"
     gene            3430..4770
                     /locus_tag="PC366_003590"
     CDS             3430..4770
                     /locus_tag="PC366_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDF2579070.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKRISNKKINFCM
                     VGIIVFADIIYFFDVPPNIRVIISMIITIAFYKISYDVGFIKSVLISLIYWMLLIATD
                     ALSISLTVWLNSINDMSSMGTGDIYRIESIILGKILLIVSLFLYRALKIKLNIEINKR
                     TLFYIVIPIVANIASFFVIFEYIFNPGSGSLIHNFQFVMISVVLLISSITLVLIAKKL
                     QQYNTLVVENNMIKNTLKYENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDKNDIELKIGINFSCCEAVELV
                     DICHIFSNILDNAIEACNKIDSGNRVICVKGDVMQNFYLIRVENTKMNKIITKNGDIL
                     TDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKAVNHVI"
BASE COUNT         1781 a          532 c          717 g         1793 t
ORIGIN      
        1 taataacaat tcaaaataaa taacttatgt aagaaccgta ggaactacgg ggatagcctg
       61 tggagaatta gtaagacata tgttagtatg caaaattcta tgaagcagga accctgtgac
      121 tttagtcatg ggaggttcag attttggctg aagatgaaga aaataatcat ataaatattg
      181 agatgcaaag agcttttgag aacgattatt tggaaagagc tgaatattat cttagtcgtg
      241 tacatggtag aaagttagaa gaaggtaaag agtataaaga aattggaaaa actattggaa
      301 tacatatact aaatcatgta aaatataatc acatagaaga ttatgtaaat tgcctgagat
      361 taacaatgga cgagcatcca gatatttatt ctagtaaaac tgcattatat tttatagagc
      421 ttccaaaaat tcataaatct gactatatag taaatagaat tatgctatgg ggaaaactta
      481 ttgataatcc ttctagctca gatgtaagag ttatagctaa gaatgattct attattaaaa
      541 aagcacttga tagattaaaa gaattaggta gcaatgaaga atatttatta aatctgaaaa
      601 gaggtgctta tatcatgaat aaaagtagaa attttaaaga agagattgaa agagagacag
      661 caattagagt tgcaaaagaa aaagattata aaataattat aatgttgaaa aaaatggttt
      721 taaattagat gacatattga ataaatttaa tgattttgac ttaagtgaag atgagataaa
      781 agaagtatat gaaaataatt gatgataaat aaaaagtgaa cttatataag tttgctgaat
      841 ctgagcctgg aaatatttat gtgtattttt taatgaataa aaatttattt taaaaacaat
      901 aattagaggt acagttaatt atatttttat gatactgtac ttctagtttt ttctattgta
      961 gatttattat ttactaataa atctacaata gaagtgcttt tgttgtaaga atcattttat
     1021 ctaatgattg ttttttataa tagttaaatt tccatttgta gtgcttaaat ataaatttgt
     1081 aataccattt ttataagtgt ataaatcact atgacgattc aactcaaagt cactgtccaa
     1141 aacaccagaa accttatcaa aatttaaagt gaaacctgga ttatcaggaa tagacaaatc
     1201 gacattggca gaagtagttt cacagtacag agaagacaac attttgctag aattgatttt
     1261 tatattactg ctagttgact cagctttaat gtcagaaaaa actccagata agttcatttt
     1321 tccagaaact gaactacaag taagattttt attgtatata tcttttaaat ttatattgcc
     1381 attagttgtt tctaagttta aaacatcaat tttcccagaa agctgtattt caccagatgt
     1441 tgatttgagt gtagcatttt tactatttag ttttgttata tcaatgtgac cactagttgt
     1501 gtctaaattt attttattaa tattaccaga gagacctatt gcacctgaaa ttgtgttagc
     1561 ttcaactgta ttacttctta tgtaagtgct atatatatct gctgaagtag tatataaggt
     1621 tattttatca taaagcttat tgggcaaata tagttcaagt attgttggtt ttggaagatt
     1681 aattccaatg aagaattttt tagttgaatt atcatatata gaaagagaat ttccgtcaac
     1741 cattattttt gctagttttt tctttgagaa attactaggg attttttgaa ttaatttgat
     1801 tttattagaa tcacttctct taattctaac ttcacctgaa atccaatcaa cattaatgtc
     1861 atttatttta tctgaaaaac tttcattttt agccactata tagttatcat aattgtattt
     1921 aggattaaga gtattaaaag ggaaattaaa agaatgtgaa attatagttc ctataaggag
     1981 tgagataaat acaatagaaa gtgatattgc caggatactc cagatgaaaa tctttgcctt
     2041 tataagcttt ttattcatat ttatcctcct ccttgtagcc ttttagttgt ataattcctt
     2101 tgacaatgtt gacaccagca gcacctatta taaatagtat ccacgaaaag gaccaaatat
     2161 taaatagtat gcttgtgatt agatatatag aaactactat aatccaatat gcattcataa
     2221 atgatttata aactggattt atatgattat aattttcctc aaaatcctca aattctttga
     2281 atttatttga taaattatca ttgtatagag catagtttgt ccttgtcatt tgattataga
     2341 ctaataaacc tactccaagt gctattaata tgagcattaa aagaatagct atagttggtt
     2401 ctatgccaaa acttacaact gagactacaa ataggaaagg gcttattata aaaagagcaa
     2461 ctgctattga tgctcttaag gctcttttct ttttttcttc aattaattca gaaggtagag
     2521 aatatggttc cttaacactt tcaattaact cagataaatc accaattcct gagattactg
     2581 agttatatgc ttcttgttct gttttaccat cttgtatttg gtcgttatac ttttctttta
     2641 gattttcaaa taattcatct ttaagttctt tgactttttt tgtctcatta actcctgtaa
     2701 agctactgtc aatataagta cgtattttgt ctaacatatt ttcacctcct aaattaatat
     2761 atctatcaat gcttttgtat tattccattc ttcacggctt tttatatatt tctctttacc
     2821 tatgtttgtt attgaataat actttcttct agctccagta acttcatcac cccaataaga
     2881 ggttattgca ccagattgtt caagtctacg aaatgctgta tacaaagtag cttctttcaa
     2941 ctcatacaat cctttggttt tttcaagtat agatttatta atctcataac cataactgtc
     3001 tttttcaagt aaatgtttta agataattgt ttctgtatga cctcttatca tgtcagatgc
     3061 gattatcatg aaaatcacct ccaattaaat atataatact ttgatatact tcgcctgtca
     3121 aggtatatca tgagaaaaga cattttattg taatatttat aaggttttat atagaaataa
     3181 tgtaaaaact ttataaataa tatattttat acctagttat agataacttt atatagttat
     3241 tattaaaaaa agcaataaaa agtttaattc aatttagcaa atttagtgat ataattaaaa
     3301 aagaaaagaa atatggactt atttggaata attttgacaa tctatttact acacgtgtag
     3361 agtcgtatat aattaaatta tacataaaat ataaaaaaat aatttagtaa tacgttagga
     3421 gaaagtatta tgataaagtc aagcttattt tggaatattt tcattgcgat atcctttatg
     3481 atagaatggt ttctttgtaa gaaaatgcta gattatacaa gtgagaaaag gatttctaac
     3541 aaaaaaataa acttttgtat ggtaggtatt attgtttttg ctgacataat atattttttt
     3601 gatgtacctc caaatataag agtaattata tctatgataa ttactattgc attttataaa
     3661 atctcatatg atgtgggatt tataaagtct gtattaatat ccttaattta ttggatgtta
     3721 ctaatcgcca cagatgcttt gagtatatct ttaacagttt ggcttaattc tataaatgac
     3781 atgagtagta tggggacggg agatatatac agaattgagt ctataatatt gggaaagata
     3841 cttttgattg tgtctttgtt tttatataga gccttaaaga taaaacttaa tatagaaata
     3901 aataaaagga cattatttta tatagttatt cctatagtcg ctaatatagc atcttttttt
     3961 gtaatttttg aatacatatt taatccaggg tctggtagct taatacataa tttccaattc
     4021 gttatgattt ctgttgtatt gcttatatca agtatcactt tagttttaat tgctaaaaaa
     4081 ttacagcaat ataatacttt agttgtagaa aacaatatga ttaaaaatac tttgaagtat
     4141 gaaaatgagt attatgaaga tatagaaaag aaatatttaa aaactagatt actaagtcat
     4201 gatatgaaaa atcacatact gtgtataaat gctatgatta aaaaaggtat tgatgttact
     4261 tcttatttaa ataatttgca ggtagaaatt cagagtaatg acttgttatt taatactggt
     4321 aattttatat tagatgctat attaagtgaa aagaaagaag tttgtgataa gaatgatata
     4381 gaactaaaaa taggaataaa ttttagttgt tgtgaagctg ttgaattagt agatatatgt
     4441 catatatttt caaatatttt agacaatgca attgaggcat gtaataaaat tgatagtgga
     4501 aatagagtta tttgtgttaa aggtgatgtt atgcaaaatt tttatttaat aagagttgaa
     4561 aatactaaga tgaataagat tattactaaa aatggagata ttttgacaga caaaaaaggt
     4621 tctcttcatg gacttggaat aaaaagtgta aaaaactctg taaataagta tggtggtaat
     4681 gttgtaattg aatatgatga taaaaaattt gtagttaaaa ttgctattcc acttagaaat
     4741 gtgaagaaag cagttaatca tgtgatttaa atgtatataa atttgatgtg tagaaattta
     4801 atatataaga attaatgtat aaa
//
LOCUS       DAMJWO010000156         4786 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.161, whole genome shotgun sequence.
ACCESSION   DAMJWO010000156 DAMJWO010000000
VERSION     DAMJWO010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4786
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.161"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            22..420
                     /locus_tag="PC366_003591"
     CDS             22..420
                     /locus_tag="PC366_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2579071.1"
                     /translation="MIKKIEHVVITNNNIENYINFYKKFGFSSKEMSEKYKLKARNVK
                     INLNIKGYKFLPYVKNLKASRDNLCFKINTNIDEPKKYLEQNEIQIKRGIVECTGVFG
                     NMKSIYLKKTNGNLIELSNHRITESKPWKI"
     gene            408..1346
                     /locus_tag="PC366_003592"
     CDS             408..1346
                     /locus_tag="PC366_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HDF2579072.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDTHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFKLMAVAVIIIFSIFLILVFIIPKIEKDNKTRGALIQ
                     GVFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVVILEIFRGGKVNIRH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHIKTIILGVCGKLILVPSIFLPISIFLGFRNVELTSLMIMLSAPTAVSSFTMAQQ
                     MDSDSELAGQIVVFTSGFSIITVFLIIFILKQNNLI"
     gene            complement(1730..1954)
                     /gene="secG"
                     /locus_tag="PC366_003593"
     CDS             complement(1730..1954)
                     /gene="secG"
                     /locus_tag="PC366_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HDF2579073.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(2072..2578)
                     /locus_tag="PC366_003594"
     CDS             complement(2072..2578)
                     /locus_tag="PC366_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2579074.1"
                     /translation="MNLEIIRATSENAIEMGFIHSCSWRKAYKGIIPDKIIDEFTSEK
                     RAEVFQSVIPKAEEEYYLFKVNGIPAGFASLNRSQEDNAPKCVGEIYSIYFHPDFWGT
                     SVTKKGLQFCIDRLSNLGYSYITIWVLKDNTRAINFYKKNGFTCDDFEKEIHIGKKLL
                     EVRYSKKI"
     gene            2663..3091
                     /locus_tag="PC366_003595"
     CDS             2663..3091
                     /locus_tag="PC366_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDF2579075.1"
                     /translation="MNPVKELNNLWHIVSMQMKTEMCSGKYPTIHGISLVELSILEIV
                     EQYPNSMMKEISEILELPKSTLTSAVKRLELKKFIKKNPCIKDKRRYNLVLTELGLKA
                     QQEHRDIEIIVFRNLLHQLDKDEIETFIRIFSKAVNKSKK"
     gene            complement(3211..4503)
                     /gene="eno"
                     /locus_tag="PC366_003596"
     CDS             complement(3211..4503)
                     /gene="eno"
                     /locus_tag="PC366_003596"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HDF2579076.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTERLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
BASE COUNT         1647 a          764 c          575 g         1800 t
ORIGIN      
        1 ataaaatctt aaggagttgc catgataaaa aaaatagagc atgtggtcat tactaataat
       61 aatatagaaa attatatcaa tttttataaa aaatttggtt tttcatctaa agaaatgagc
      121 gaaaagtata aacttaaggc tagaaatgtt aagataaatc ttaacataaa aggttataaa
      181 tttttacctt atgttaaaaa tttaaaagca agtagagata acttatgttt taaaataaac
      241 acaaatattg atgagccaaa aaaatactta gaacaaaatg agattcaaat taagcgagga
      301 attgtagaat gtacaggtgt ctttggtaat atgaaatcta tttatttgaa aaaaactaat
      361 ggaaatttaa ttgaattatc aaatcataga atcacggaga gtaaaccttg gaaaatttaa
      421 tcctatcaat aaatgttgtt cttcctttgt ttctcacaat gtcacttgga tatgttctaa
      481 aaaaattagg tctatttgat actcatactt taaataaaat gaataatgtc tgcttcaagt
      541 ctttcttgcc attattatta ttttttaata tatacaatac agatttagat ggttctctta
      601 attttaagct tatggctgta gctgttataa ttattttttc aatcttctta atcttagtct
      661 ttattattcc taaaattgaa aaagataata agacaagggg tgcattaata caaggtgtat
      721 ttcgtagcaa tttcgttata tttggtattc ctgtgacaat ttcactattt ggcgataaga
      781 gtattggagt cacatcttta ttaattgcag ttattgtacc tatgtttaat gtattatctg
      841 ttgtaattct tgaaattttt agaggtggca aagtaaatat aagacatatg attaaaagcg
      901 tcttaacaaa tccactcata atcgcctctt ttataggatt gacaatgcta attttaaata
      961 ttaatatacc tacattttta cacaaaacta ttggtgatat ttctaaaata gctactcctt
     1021 tatcacttat aattctaggc ggatctttta gtttttctgc tataaagggg catataaaaa
     1081 ccattatatt gggcgtatgt ggaaaactta tacttgtacc ttctatattt ttaccaatta
     1141 gcatttttct tggatttaga aatgtagaat taacttcact tatgataatg ttatctgctc
     1201 caactgcagt ttcttcattt acaatggcac aacagatgga ttctgacagt gaattagctg
     1261 gacaaattgt agtatttact tctggatttt ctataattac agtattttta ataatattta
     1321 ttttaaagca gaataatctt atttaatgat atttgataac acaaattggt attatgagaa
     1381 acatatataa aattgattta attgcgtaaa aacatattat tatactattt ttactatata
     1441 atataacttt gtgtatatta tctcattaaa catggtgaaa gtagtgttgc tatatatttt
     1501 ttagtttgaa aaaaatatat aaatataaac aatatataaa tacaaataat aaatgccaac
     1561 aaatagtcaa tctataaaat aaaaactgga ctaatcatat aaaatcatta gtccagcttt
     1621 tattttacgt actttttatg ttgatgtact tttattaaaa actaaattta atttttaaat
     1681 atctagcaaa tgcactaatt aaataatggc cagttattca acaatatcac tacttcttaa
     1741 ctataagtaa tgccaatgca tttataaaaa ataatactgc tgttatcttt gtaactctag
     1801 caagaaatgc ttgttttcct tttggtttaa agtaagcttg acttccttct ccaccaaatt
     1861 ctgaaggtaa agcatttttt gaatcttgag gcattatgct aattactagt aaaatcccta
     1921 gcactacttg cacacccatt aaaatgttgc tcattattgc ccctcctatc tatttattac
     1981 ttaaatttca ttactcttta gtgtatcaca ataatatagt catttcaaga ctattgaagt
     2041 ataaataaca aacaaaaata atatgcaatt actatatctt ttttgaataa cgtacttcta
     2101 ataatttttt tccaatatgt atctctttct caaaatcatc acaagtaaaa ccattttttt
     2161 tatagaaatt tatagctcta gtattgtctt ttagaaccca tatcgttata tatgaatatc
     2221 ctaaattgct taatctatca atgcaaaatt gtaatccttt ttttgtcaca gatgttcccc
     2281 aaaaatcggg atggaaatat atagaatata tttctccaac acattttgga gcattatcct
     2341 cttgacttct atttaatgaa gcaaaaccag caggtatacc attcacttta aaaagataat
     2401 attcctcttc agcttttgga ataacacttt gaaaaacttc tgctcttttc tcagaagtga
     2461 attcatctat tatcttatct ggaataattc ctttatacgc ttttctccac gaacaagaat
     2521 gtataaaacc catttctata gcattttcac ttgtagctcg tataatctct aaattcataa
     2581 aaacaccatc ctattgacaa attaatacga ttatcgtact atattagtgc gataattgta
     2641 tcatatatgg aggtaaaagt caatgaatcc tgtaaaagag ctaaacaacc tgtggcatat
     2701 tgttagtatg cagatgaaaa cagaaatgtg tagtggtaag tatcctacta ttcatggtat
     2761 ttctttagta gaattaagta ttttagaaat agttgaacag tatcccaata gtatgatgaa
     2821 agaaattagt gaaattttag aattgccaaa aagcacatta acaagtgctg taaaacgtct
     2881 tgaattaaaa aaatttatta aaaagaatcc ctgtattaaa gacaaaagga ggtataactt
     2941 agtcttaact gaattaggtt taaaggctca acaagaacat agagacatag aaataattgt
     3001 atttagaaat ctcttacatc aattagataa agatgaaata gaaactttta ttcgtatttt
     3061 ttctaaagct gtgaataaaa gtaagaaatg aaatataaaa aaaggataag tgaattgaaa
     3121 aatcaactat cacttatccc ttataagata aatttttatc ttttatgtta tctttttaat
     3181 ctttaatgcc atatttttaa tcttcaataa ctattttttt aaattataga aagattttaa
     3241 tccacagtat ctagcttgtt ctccaaccat ttcttctatt cttaataatt ggttgtactt
     3301 agcaactcta tcagttcttg atggagcacc agtttttatt tgaccagcat ttactgcaac
     3361 agctaaatct gctatagtag aatcttcagt ttctcctgat ctgtgagata taacagcagt
     3421 atatcctgct ctcttagcca tttctatagc atctaaagtt tcagttattg tacctatttg
     3481 attaacttta actaatatag agttagctac tccattttca attccttttt ctaatctctc
     3541 tgtgttagta acaaataagt cgtcaccaac taattgtaat ttatttccta atctttcagt
     3601 taataacttc catccgtccc aatcttcttc gtctaaacca tcttctatag ttattattgg
     3661 gaagttgttt gaccaatctt catataaagc aaccatttca gcagcagtta actcttttcc
     3721 ttctcctgct aaaacgtatt ttttagtttc tttgttgtac atttctgtag cagcaacgtc
     3781 aagtcctaac ataacatctt cacctggctt atatccagct tttgttatag cttcaactat
     3841 taattctaaa gcttctctgt ttgaacctaa gtttggagca aatccacctt cgtcaccaac
     3901 accacaagct aatccttttt ctcctaaaac tttctttaat gaatggaata cttctgctcc
     3961 cattcttaaa ccttctttaa agcaacaagc tcctactggt aatatcatga actcttgaac
     4021 atcaacgtta ttatcagcat gctctccacc gtttaatatg ttcatcattg gaacaggtaa
     4081 ttgtttagca tttactccac ctaaatattg gaataatggt aaacctattt catcagcagc
     4141 tgctctagct actgccattg aaacacctaa tatagcatta gctcctaatt tacctttgtt
     4201 tggagttcca tctaattcta tcatgattgc atctatagct ggttggtcaa atgcatccat
     4261 tccttctatt tcaggtgcta ttatttcatt tacgttagca acagctgttt ctacaccttt
     4321 tcctaagtat cttcccttat ctccatctct taattcaaca gcttcaaaag ctcctgtaga
     4381 tgctcctgat ggaactattg ctcttcccat tgctccatct tctaatacta cttcaacttc
     4441 tacagttgga tttcctcttg agtctaatac ttctctagca tatactaatt caataactga
     4501 catttgtata tctcccttcg attttctatt agttaaattt tcatttactg taaacatccg
     4561 tctactattt taatctactt tctatattat agtacataaa gttgcttttg aaaattaggt
     4621 acaaatttat ttgatgggta aatttgtaaa agttcctatt tttattttat tttttataat
     4681 attttaattt atataatata aaaaaacttg tctaaaatcc aaaaccaatc ttaaatacac
     4741 aaatattata actagattta aaacattaaa cataaaatgt acaact
//
LOCUS       DAMJWO010000157         4557 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.163, whole genome shotgun sequence.
ACCESSION   DAMJWO010000157 DAMJWO010000000
VERSION     DAMJWO010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4557
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.163"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            202..1008
                     /locus_tag="PC366_003597"
     CDS             202..1008
                     /locus_tag="PC366_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDF2579077.1"
                     /translation="MGMILSTLGINLYLAPAKLLSGGVAGICVILYKLFGINQGISSF
                     LMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLTQDIAKYFPIDDTMLQCIYGGAL
                     TGIGMGLTFKARATAGGLDIIAAIMKRKYDIPMKNTFLFINFFVVCAGAFLFGAKLVM
                     YTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEISKVIMNKMGRGVTFLEAEGAYT
                     QNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNNVEEVKGGGFKDKFL"
     gene            1135..1407
                     /locus_tag="PC366_003598"
     CDS             1135..1407
                     /locus_tag="PC366_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579078.1"
                     /translation="MLRERFVVRNHHNPHTSGCCGTGGEGCCGGDNHEHSHQHSHSHG
                     HEHEHVNGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDGHTHEHK"
     gene            complement(1570..2142)
                     /locus_tag="PC366_003599"
     CDS             complement(1570..2142)
                     /locus_tag="PC366_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2579079.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKDDIIYDIADTHLEVITSAILNCVKNVKSKNSQIEMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERIRLKYIEWRTTLKSEIVESLEKYNSSENEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLVNHWI"
     gene            2326..3168
                     /locus_tag="PC366_003600"
     CDS             2326..3168
                     /locus_tag="PC366_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDF2579080.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNETFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKVEVIDSLSGSIGIGQLVLKAAILIKEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEIGSVMGTYTSKGAIL
                     ITAI"
     gene            complement(3271..4347)
                     /locus_tag="PC366_003601"
     CDS             complement(3271..4347)
                     /locus_tag="PC366_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDF2579081.1"
                     /translation="MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
BASE COUNT         1663 a          587 c          711 g         1596 t
ORIGIN      
        1 ataaatatat taaaagaagg attaagacta ataacaattc aaaataaata acttatgtaa
       61 gaaccgtagg aactacgggg atagcttgtg gagaattagt aagacatatt ttagtatgca
      121 aaattctatg aagcaggaac cctgtgactt tagtcatggg aggttcagaa taacatattt
      181 ttacaatatg gtctgattat attgggtatg attctatcaa ccttaggaat aaatttatat
      241 ctagcaccag ccaagttatt aagtggagga gtagctggaa tttgtgttat attatacaaa
      301 ttatttggta taaatcaggg aatatcaagt ttcttgatga acataccaat atttattata
      361 gctagaaagt attttgataa taaatttttg ctaataagtt ttgtcaatat gttactgttt
      421 tctctagcac tggggctaac acaagatatt gctaaatatt tcccaataga tgatactatg
      481 ctacagtgta tttatggtgg tgcattaact ggtataggta tggggttaac ttttaaagca
      541 agagctactg ctggaggact tgatataata gcagccataa tgaaaagaaa gtatgatata
      601 cctatgaaaa atacattttt atttattaat ttttttgtag tatgtgcagg agctttctta
      661 tttggagcta aattggtgat gtacacttta attacaatgt atataatttc ttttactatg
      721 gatataggaa aagattgctt tgatagaaaa aaatctatac ttttaatatc aaataaatat
      781 gatgaaatat ccaaagtgat aatgaataaa atgggtagag gagtcacttt tttggaggca
      841 gaaggtgcat atacacaaaa taagaaaaag atgatttatt gcataatatc tgcaaatgaa
      901 ataggtaaat ttaaagattt aatttatgat atggatagtg aagcttttat ttctgtcaat
      961 aacgttgaag aagtaaaagg tggaggtttt aaggataaat ttctttaaga ttatatatgt
     1021 taattatata tgttaaaaaa tgccatatgt attgagatta tacctagtta gatgtatact
     1081 gtagttaatg gggtacatga agtattcaat aatatactag gaggtataag aattatgtta
     1141 agagagagat ttgtagtaag aaatcatcat aatccacata caagtgggtg ttgtgggact
     1201 ggaggagaag gatgctgtgg aggagataac catgaacatt cacatcaaca ttctcacagt
     1261 catgggcatg aacatgagca tgtaaatggt gtaggtcacg accataatca tgatgatggt
     1321 ttttcaggta ctcatgagca tagccatgag catacacata cacatggtca tgaacattca
     1381 gatgggcata cacatgaaca taaataaaaa cattttaaat ttataagaga tttttatttt
     1441 gtgattccat gaaggtttaa ataaaaattg aatgttttaa gtaaaaatta ttgagaataa
     1501 ataagaaagt gaactgttaa agtagataac ttaaatagtt cacttttatt aattatctaa
     1561 gtattaagtt taaatccaat gattaactaa aaaagaagct atattttcat aaggtatttt
     1621 ttctgttttt aataaacttt ggacaactaa accatcaact attgacatga gtaaaaaaga
     1681 aaatgattca gcatcctgtt cattttcgct actattatat ttttctagtg attcaacaat
     1741 ttcagattta agagtagttc tccattcaat atattttaat cttattcttt cctttaaatc
     1801 attatttgaa gtaattgcct cacaaataag atacatatgt accctaccac gactttctat
     1861 agtagatatt ttctctaaga ttaagttaac catttctatt tgagaatttt ttgatttgac
     1921 attttttaca cagtttagta tagcactagt tataacttct aaatgagtat ccgcaatatc
     1981 atatataata tcatctttag atgcgtagtg ataatacaaa gtacctttac ttatatttac
     2041 atcttttgca atatcagcaa ggctagtatt ttgaactcca tttttggcta ttaaattggt
     2101 tgcagatgat aaaatagcct gtttcatatt atttgttttc ataaaaccta cctttccatg
     2161 tatatttata acaaattaat aacattataa gcttatgaat atttattgtc aataaagcga
     2221 gaatctatat ctattgactt tttttcattc aatatataaa ataataatta aatcggtcgt
     2281 acgaccgact gaataaataa aataatatct tatagtgagg ttaatatgga taaaataaaa
     2341 ttgatagtgg acagtgcatg tgacttacct gatgatataa tagaaaaata caacatagaa
     2401 gttgttggtt taaatgtatc ttttggagaa gaaagttata tatctggaaa ggaaatagat
     2461 aatgaaactt tctatagaaa aatgagtgag agtaaagtac taccaaaaac atcatgtcct
     2521 tctcctgata aatttttaga agcataccat tgtcaggaag aaagtgtatt ggtgattaat
     2581 ataagttcag gattatctgg gacttataat agtgcacttt tagcaaaaga tatgtttgaa
     2641 aaggaaggaa ataacaaaaa agttgaggtt atagattcac ttagtgggtc aattggaata
     2701 ggacaattag tgttaaaagc agcaatatta ataaaagaag gaaaagaaat tgaagagatt
     2761 gtttcaataa taaataaata taaagataat cctccatttt ttggaacact tgaaacttta
     2821 gaaaatgcta ttaagggtgg tagaataaat ccaatagcag gaaaaattat aaataccttg
     2881 aattttaagg cgataataca agttgcagat ggcgttgtaa ctcctataga taaggcaaga
     2941 ggtgaaggaa acagtttgaa aaagctgatt actttagtag agtcaaaaat taaagataaa
     3001 gaagaaaagg ttttatttat aggacatgct aattgcccag aaaaggctca aaaggtaagg
     3061 gaagttatgg aaaaggatgt aaaatacaaa gatgttgtaa tctgtgaaat tggttcagtg
     3121 atggggacat atacttcaaa gggtgcaatc ttaataactg caatataaat aatggattga
     3181 aataaatcat agattgagaa attaaagcca tataaaaatg tttaaaacat ttttatatgg
     3241 ctttttaatt ttatcaaatt gattttagaa ttaaccaact acacatattt ctttgtcatg
     3301 tttgtttaat atctcacaac catcttcagt aacaagtact aaatcttcta ttctaactcc
     3361 gaactcacct ggtaaatata tacctggctc tatagagaat atcattcctg gttgtacagt
     3421 atctgtattt atagaagata catctccttt atcatgaact tcaagtccta tagagtgacc
     3481 agttctatga gtgaagtact gtccatatcc cttttcagtt atgtagtcac gagcagcagc
     3541 atctatatca cagaatctaa cacctggttt tacaatagct tcagctctct tattagcttc
     3601 aagaactatt tcaaatattt ctctaccttt ttcaggtatt tctttataga atacagttct
     3661 tgtcatatca gcacaatagt tatcttttat acaacctata tctaatatta ttgcatctcc
     3721 tggtttcaca agtgcatttc caggttcacc atgtggatta gctccattag gtccaaaacc
     3781 tataataggg tcaaatgaaa atccatcagt acctaggtct tcatatattt tagataattt
     3841 accaacaagt tgtttctctg taagttcacc agaaacagta gctttaagtt gttccatagc
     3901 cttgtcattt aattttgaag ctattctcat taactctttt tcttcttcat ctttacacat
     3961 tcttaaagta tctattatat aagatgaatt tacaaactta cttcctccac ctaattctat
     4021 taagtttaat aagaatctag ctggccagtt tttatcaaca cccatagtag catttttgtc
     4081 tatatgttca gttattattt ctactggatt ttgagtatca ttaaaccaaa ccatttcaac
     4141 acctaaatct tctgaaactg ggaataattc atttataaat aatttattat tgccatttaa
     4201 atttaagtat aatgctaata atctttcacc tggatggatt agtactcctg taagataaaa
     4261 tatagaagta gggtcactta ctaacatttg agaaatatca tcttttttca tttgttcaag
     4321 tacagcattt aatctttgag ctttcataat aatttcctcc taatcaaaat tcaatacaaa
     4381 tcaattttag cattattaaa caaaaaagag tatacttttc ttctagaaat ataaaaaaag
     4441 tttgttatat attttttata ttaagtttaa tctctacttt tgcattaaat acggaagtaa
     4501 aatgactttt tattgtgaaa attctataaa agtaataaat taagtctata aagttat
//
LOCUS       DAMJWO010000158         4545 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.164, whole genome shotgun sequence.
ACCESSION   DAMJWO010000158 DAMJWO010000000
VERSION     DAMJWO010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4545
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.164"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            190..1665
                     /locus_tag="PC366_003602"
     CDS             190..1665
                     /locus_tag="PC366_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDF2579082.1"
                     /translation="MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
                     RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
     gene            1752..2165
                     /gene="speD"
                     /locus_tag="PC366_003603"
     CDS             1752..2165
                     /gene="speD"
                     /locus_tag="PC366_003603"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HDF2579083.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            2195..3046
                     /gene="speE"
                     /locus_tag="PC366_003604"
     CDS             2195..3046
                     /gene="speE"
                     /locus_tag="PC366_003604"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HDF2579084.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            3036..3914
                     /gene="speB"
                     /locus_tag="PC366_003605"
     CDS             3036..3914
                     /gene="speB"
                     /locus_tag="PC366_003605"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HDF2579085.1"
                     /translation="MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDV
                     LDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISDKIK"
     gene            complement(4094..4294)
                     /locus_tag="PC366_003606"
     CDS             complement(4094..4294)
                     /locus_tag="PC366_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDF2579086.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
BASE COUNT         1809 a          503 c          775 g         1458 t
ORIGIN      
        1 aaaagtttat aaatattgat atagctaatg tatatgtttt tgagtaactt caaaaaaaca
       61 cttgtaaaaa tgctggaatg ttaatataat aaatatcatg agtttaataa aagtaaaaat
      121 aaaaaataga aataataaat aataaatatt aaaaatattt gaatatagag aggagatgaa
      181 tttgaaatca tggatagcga gtttgcaaat gcagttgaat taagctatga gtgtgctcca
      241 ttattagagt cgttaaagga atactcagag aaagatatag cttgttttga tgttcctgga
      301 catgtaaaaa atagaggtgt agctatatta aataaatatc taggtgaaag tctcatgaaa
      361 atggatataa attcatcacc aactatggat aatgtatctg cgccaaatgg gattataaaa
      421 aatgcacaag atttgctagc acaagcatat atggctgatg aggcattctt tataacgaat
      481 ggcacaactc aagcaataca tgcaatgatt ttgagtgtta taaaaccagg tgaaaaagta
      541 ttacttccaa gaaatataca taaatcagta ataaatgcgt taatactttg tggaggaata
      601 ccaatattta tacaaccaga atttgatgaa aaactaggta taagtttaaa tattactctt
      661 gaaaaagtta gaacagagat agaaaaagat tgtaatataa aagcattatt tttccttaat
      721 ccaacttact atggagtttg tgcagacctt gagagtatta tagaactatg ccataaaaat
      781 aatgttttag tgttagttga tgaagctcat ggtgcacatt ttccatttca tttagattta
      841 cctccttctg caataagttt aggagctgac atggtagctg taagtataca taaaactgga
      901 ggagcattga cacaatcttc agcactctta ttgaatagag ataatgtaag ttttgaaaag
      961 gttcttcaat caatcaatat gctacaatca acatcagcat cttatttgct tatggcaagt
     1021 atagatggtg ctagagttaa tctagttgag aatggtgaaa agcaactgtc aaaagcatta
     1081 aatctatcta ggtatgcaaa atctaaattg aacaaaattg atggaataaa agttttatct
     1141 acagaaatat tgaaacaaaa aggtgttaaa tttatagatg aaacaaaatt gtgtataaat
     1201 gtaaaagaat taaatttgac tggatttgaa gtatacgatt tattatataa aaatttttca
     1261 attcaagtag aattgggaga ttcatataat atactggcac ttgtgtccat tggaacaaat
     1321 aaatcagata tagatagatt agtaaaagca ctttctataa ttgcaaagat ttatagaaaa
     1381 gaatcaacat taaatgaatt taatatggtt caaataaatc caattattaa acttaatcca
     1441 agagaagctt tttatgcacc aaaggaaagt gtagaaatca attcatgtat agatagaatt
     1501 tgtggagaat caataatggc atatccacca ggtataccga ttattgctcc aggagaattg
     1561 ataacagaag aaattatgga gtatattatt ttcttaaaaa atagcaatgc gtatcttaca
     1621 gatgtacaag ataaaaactt agatagaata ctagtaataa aataaattac tttattttgc
     1681 aagggcaagt gtttgttaag tagagtttat caaatagaac ttattaaaag tataaaggag
     1741 ttggggttga aatgaaattt gaaacactag gaagacatat actagtagaa tactataatt
     1801 gtgatgaaaa cgtacttaaa gacccacgtc ttatagaaaa ttttatgaat gattcagcat
     1861 taaatgcaaa agcgacaatt gtggattctg tattccacca ttttaatcct tggggggttt
     1921 caggagctgt tataattgct gaatctcatt tgacaataca tacatggcct gaatatggtt
     1981 atgcagcagc agattttttt acttgtggtg atatagaccc atggaaaagt tttgaattat
     2041 tagagcaact tttaaagtct gaaagaagcg agtctacaga aattccaaga ggcttaacta
     2101 caaaaattaa aaaatattca aaaaaagatt taggtaagat tactcataaa ccagaagcag
     2161 tataaaacat acaagagaaa gtgaggatta ttatatggaa ctttggtata cagaagaatg
     2221 gacagaaaat gtaagatttt ctataaaagt aaataaacat ctatttgaag gaaagtctca
     2281 atttcaaagg atagatgtat ttgatagtga tgaatttgga aaatttctaa caatagatgg
     2341 attaatgatg gtaacatata aagatgaatt tatataccat gagatgataa ctcatgttcc
     2401 tatggctaca aatttaaaca taaagaaagt attagtcata ggtggaggtg atggaggtac
     2461 agtaagagaa ttaagccgtt atcctcaaat agaaaagatt gacatggttg aaatagataa
     2521 aatggttgta gatgtatcta aggagtatat ggatatatgc tcatgtaaat tagatgataa
     2581 aagagtgagt ttatattttg aagatggtgt taattttgtt aagtgtgcac atgataaatc
     2641 atatgacctg ataatagtag attcaactga cccaatagga ccaggcgaag ggcttttctc
     2701 aactgatttt tataaggatt gttatagaat actgactgat gatggaattt tagtaaatca
     2761 aagtgaaagt ccgtattttg actttaatgc taaagagatg aaaagagcta ataaaaaatt
     2821 aaaacagata tttccaatat cagaagttta tcaagcacat ataccaacat atccatctgg
     2881 tcactggttg tttggatttg cttcaaaaaa acttaatcca gtaaaaaatc aagatagaaa
     2941 tggatgggag aaattaagtt taaaaactaa atattataat agtgatatac atttaggttc
     3001 gtttatgtta cctcaatacg tgaaggagat gctagatgaa gaataatttc tatcatatga
     3061 acacttttat gagtatggac aaaaattatg aagaatctaa tcttatagta tttggtgttg
     3121 gatttgatgg aactacttct aacagacctg gggctagatt tgcaagtagc tctatgagaa
     3181 aagaatttta cggtcttgag acatatagtc cttttttaga tttggactta gaggattata
     3241 atatatgtga ttatggagat ttagaaatta gtgttggaag tacagaacaa gtcttaaaag
     3301 aaatctatca agagacatat aagattgtta gagattcaaa ggtacccttt atgattggag
     3361 gagagcattt agttacatta ccagccttta aagcagtaca tgaaaagtac aatgatatat
     3421 atgtaattca ttttgatgcc catactgatt tgagggaaga atataataat agtaaaaatt
     3481 ctcatgcaac agtaattaaa agaatatggg atattgtagg tgataataaa atatttcaat
     3541 ttggtataag gtctgggaca aaagaagaat ttaaatttgc tacagaagaa aaacacacat
     3601 acatggaaat aggaggaata gatacgtttg aaaatatagt taatatgcta aatggaaaga
     3661 atatttatct aactatagat ttagatgtat tggatgcatc tgtgtttccg ggaacaggta
     3721 caccagaacc tggtggtgta aattatagag agtttcaaga gatttttaag attataaaaa
     3781 actctaatat aaatatagtt ggttgtgata ttgtagagtt aagccctgat tacgatacaa
     3841 caggtgtatc gacagttata gcttgtaaaa tcttaagaga gttatgctta ataatatctg
     3901 ataaaattaa atagagtatt ttatataaat agtatatatt ataatataag aagttatttt
     3961 aaaaaagtta gtttaagttt gacgcttttc taaagtaact tcttattttt gtaattaaaa
     4021 ataaatataa taaacaacaa aaaagagccc tcgatagctc cttttctaaa atatatatat
     4081 ttaaattaaa taattatatt ctatttacgt tttcagcttg aggtcctcta ttaccttgag
     4141 ttatatcaaa gctaaccttt tcgccttctt ctaaagtttt gtatccatca ttttgtatag
     4201 ctgagaaatg tacgaaaaca tcatcttctc cctctacaga tatgaaccca aatccttttt
     4261 cattgttaaa ccattttact attccgtttt tcattataag aaaacctccg cattattaaa
     4321 aaatacaaac taaaaaaata agtctgttct attaatataa cataaatttt aaataaaagc
     4381 aaataaaatt tttaaaaaaa ttaattactt ttagaattta ataaaaattg ttaaattata
     4441 cagtgagaag tattgtaaaa tttgacgaaa atgtaaatgt agataataaa tttaatgtca
     4501 aaaaatgcaa caaaaaggta tgtaagtaaa aagtaaaatt aaaat
//
LOCUS       DAMJWO010000159         4509 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.165, whole genome shotgun sequence.
ACCESSION   DAMJWO010000159 DAMJWO010000000
VERSION     DAMJWO010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4509
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.165"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     repeat_region   142..1096
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=341..369
                     /rpt_unit_seq="atttacataccacatagttaatataaaac"
     gene            complement(1292..1531)
                     /locus_tag="PC366_003607"
     CDS             complement(1292..1531)
                     /locus_tag="PC366_003607"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579087.1"
                     /translation="MECYLKRTLIIFSKAFLSISFKTRKYLFIVIFILVCPNLSEMIF
                     ILVPARRRIIRIDNIVSIYKYVGVLKLINYSILIL"
     gene            1743..3014
                     /locus_tag="PC366_003608"
     CDS             1743..3014
                     /locus_tag="PC366_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDF2579088.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIILEKGKVKGIFKEIPKEY
                     KNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPD
                     TLLENTQDSIADTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPM
                     QSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMREN
                     NVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKL
                     YWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSI
                     LERLERFIYVGDDRNIIHRYVCGKLIEEPNI"
     gene            complement(3653..4408)
                     /locus_tag="PC366_003609"
     CDS             complement(3653..4408)
                     /locus_tag="PC366_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1835 domain-containing protein"
                     /protein_id="HDF2579089.1"
                     /translation="MAHICFEDICYLLLKEAMKLKLIPHNKIVLFEDDLSIGNIFDVN
                     NYELRENIFKIRNVFENNPKLLFKPDLLEDRKLSKCRNIIIWCANNPKDLCGVYYVVS
                     KFQDKNIKIALVDEKKTEDALIRYSFTSEMSPEDFPFFLDKTLEIGFNEKLEFKNKWD
                     VLVKENSIFRALVGNEIKSVEETYFDKYILRNISDKWQPLIEVVANCMFEDEMRVKDW
                     FILWRLEKMASLKIVKIKGSKGDFYSDKEIRKV"
BASE COUNT         1725 a          631 c          495 g         1658 t
ORIGIN      
        1 ttctactttt atattttaat cattaaaact aaagtcaatg ttatctggta attatttact
       61 acaaatgata aaaaataatt atattttaaa gtagaaaatg ctgtataaat tattggggta
      121 ttttacctat acttgttgca aatttacata ccacgtagtt aatataaaac aaatttcaag
      181 cgattggaca acgaataaaa attgcaattt atatatcatg tagttaatat aaagcatatt
      241 tgtgtcgata tatagttcta actaagtata agatttacat acctcatagt taatataaaa
      301 caatgtgtcc gaattggaca catagaaagg aaaagtaaaa atttacatac cacatagtta
      361 atataaaact atgcttatat attatgttta ttctgttgtt tctaaaattt acataccaca
      421 tagttaatat aaaacgattt tttcatgcgg aggaaaattg atgtggggac atatttacat
      481 accacatagt taatataaaa cagataatct aggcacacat acaatgcgca aaactttatt
      541 tacataccac atagttaata taaaacattc agacgatata ggcgcaggag ctaagtattc
      601 tgaaatttac ataccacata gttaatataa aaccagcacg ccaagtataa gtaaaacttc
      661 cactatcacc atttacatac cacatagtta atataaaact aaatgttgct ccgtaaccta
      721 aaaacataat gctccaattt acataccaca tagttaatat aaaacgtgaa agaaaaatta
      781 atatgctatt tacattttac aaatttacat accacatagt taatataaaa ccattccaca
      841 atttatacaa ttttttctgt tctaaaacat ttacatacca catagttaat ataaaactct
      901 tcttatcttc cagttgcaaa atctatgctt gacctattta cataccacat agttaatata
      961 aaactagttt gagtggtaaa agtacgaagt acccctcttt aatttacata ccacatagtt
     1021 aatataaaac atatgtaatt caccgtttta aattatagat aaattaaatt tacataccac
     1081 atagttaata taaaacccca aaataaacta agtattttca gtacttacac acatacaact
     1141 ctctcaaatt tgcagtgaac catgagtagt gcaattgata acatttatca tacaccctca
     1201 atcccttaca ttgcaactgt taaaccctac tttatcaaaa atatcgctca ctgcaaaatt
     1261 tatatatttt tattatatca taaaattcaa actataaaat taaaatggaa taatttatca
     1321 atttaagaac acctacatat ttgtaaatac ttactatatt atctattcta ataattcttc
     1381 ttctagctgg aactaatata aaaatcatct ctgaaagatt aggacatact aatataaaaa
     1441 taactatgaa tagatatttt cttgttttaa acgatatgga taaaaaagct tttgaaaata
     1501 taatcaaagt tctctttaaa taacattcca ttttatgtaa gtaagcatta tatttttctt
     1561 aaatgtcact taagtgtcag ttatatataa taatagtaaa caactgtatt tcactaatat
     1621 ttgctattat ctaatagtat ttatagttta gatttgatat aatacatgtg gtaaaatttt
     1681 gatttgtaaa acaaaatttt acctacatat attaaaacaa atttaaaact aaggagacct
     1741 atatgttaaa agtattaaaa ggaaatataa tttttacaaa aacttcagaa actttcacag
     1801 tatttgaaaa tagttatatt atactggaaa aaggtaaagt aaagggaata tttaaagaga
     1861 tacctaagga atacaaaaac ctaaaagtag tagattacac tgataagctt ataatacctg
     1921 gtatgaatga cctccatgcc catgcctctc aatttaaaaa tcttggaatg gctatggata
     1981 aagagctttt gccatggctt gaaacttata catttccaga agagtcaaat tataaagata
     2041 tagaatatgc aacaaaaatg tataaaaaat ttgtaaaaga actttggaaa tctggaacta
     2101 caagaatagc agtgtttgca acagtacata aagaagcctc tatgaaactt atggatatat
     2161 tcaaagaagt tggtcttgga gcatacgttg gtaaagtaaa tatgaatatg aattgccctg
     2221 atactttatt agaaaacact caggattcta ttgctgatac agaagaaatt ataaataagt
     2281 atagtgatac agattctatt gtaaaaccaa taataacacc tagatttata ccaagctgta
     2341 caagtgaact tttaaaaggt ttaggagatt tatgtttaaa atataatatt cctatgcaat
     2401 cacacttatc tgaaaattat gatgagattg aatgggttag aagtctagaa cctgaatcta
     2461 aattctatgg agatgcatat aatagatata atttatttgg tcaaactcct actttaatgg
     2521 ctcattgtgt tcattgttct caggatgaaa tagatttaat gagagaaaac aatgttatgg
     2581 cagttcactg tccagcttct aactttaatg ttggtagtgg tgctatgcct atcagaaaat
     2641 taatcgataa taatattaga ttagcacttg gatcagatat aagcggtgga catacattgt
     2701 caatatttaa agcaatggta tctgcaatac aattatctaa attatattgg gttaattctg
     2761 gtaagaagta taatttctta tctttatctg aggcttttta tattgcaacc aaaagtggtg
     2821 gaagtttctt tggaaaagtt ggtagctttg aagaaggtta tgattttgat gcattgatta
     2881 ttgatgattc aaatttaaat catgacaatt attctatact tgaaagactt gaaagattta
     2941 tctatgttgg tgatgataga aatatcattc atagatatgt atgtggaaaa ctaattgaag
     3001 aacctaatat ataattataa taaaaatttt aattatatat tatggttaat ttatgcaact
     3061 ataattaata aaagagtata ttttaaatct aaaagctata ggttgaaaca tactcttttt
     3121 attttgttta tttatagctt tagttattaa tcatatataa atctacaaaa cgtattccta
     3181 gtaacttata ttttttgata tctacaatca taagactata ttattggatt catacctcaa
     3241 aaatattgcc ttctgaacat tattatattc aaagttatgt taatttacaa tgatatatct
     3301 aacatgtatt gattaaaaaa aattaaaact tgcttttcat ctcctatatc taaagaagtg
     3361 gcatttagaa taaactattg taatattaaa gttgaaattt tctagtttat ttactctata
     3421 gcaccatatt ttaatactat taagtaaaaa tgtagttaaa atatatacta atatccctga
     3481 aataagtatt tcttttttat ttagcacact tattcgtaag gtattagtta ttatattttc
     3541 aaattataga ataaatatta tacttattgc taattataat attaatactg ttaagatatt
     3601 tttcttcata gttataccca ttatttaata caatttatta taaattcaat ttttaaactt
     3661 ttcttatctc cttatcagaa taaaaatccc ctttacttcc ttttattttt actattttta
     3721 aacttgccat cttctctaat ctccaaagta taaaccaatc ttttacacgc atttcatctt
     3781 caaacataca gtttgcaacc acttcaatta aaggttgcca tttgtcactg atatttctta
     3841 atatatattt atcaaaataa gtttcttcaa cacttttaat ttcgttacct actaatgctc
     3901 taaaaataga attttcttta actaacacat cccatttatt tttaaattct agtttttcat
     3961 taaagccaat ttctagtgtc ttatctaaaa agaatggaaa atcttctgga gacatttcac
     4021 tggtaaatga atatctaatt agagcatctt ctgtcttttt ttcatctact aatgcaatct
     4081 ttatattttt atcttgaaac ttactcacta cataatatac tccacacaaa tcttttgggt
     4141 tatttgcaca ccatattatt atatttctac attttgataa tttcctatct tctaacaaat
     4201 ctggcttgaa taatagtttc ggattatttt caaaaacatt tctaatctta aaaatatttt
     4261 ctcttaattc gtagttattt acatcaaaaa tattacctat tgataaatca tcttcaaata
     4321 atacaatttt attatgtggt attaacttta acttcattgc ttcttttaat aacaaataac
     4381 aaatatcctc aaagcatata tgtgccataa aattcacctc ttttaaaatt aacaatttat
     4441 tttattataa tatataaact gtaattatca aacacttcta atctcctata ttttcatatt
     4501 aatgtaata
//
LOCUS       DAMJWO010000160         4504 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.166, whole genome shotgun sequence.
ACCESSION   DAMJWO010000160 DAMJWO010000000
VERSION     DAMJWO010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4504
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.166"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            119..766
                     /locus_tag="PC366_003610"
     CDS             119..766
                     /locus_tag="PC366_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2579090.1"
                     /translation="MNILIADDEISMLKILCAYFKKENFNVFTAKNGEEALDIFYENK
                     IDLAILDWMMPIIDGIEVCKEIKENSNTRVLMLTAKSQSEDEIEALNIGADEYIKKPF
                     DPRVLIIRAKKLINYKNTINIKDLKIDFGSSKVFKGDKELLLTKKELELIRCLINNKG
                     MVLSREKLLDLVWGLDYEGDFRTVDTHIRRLRVKIGEDIIKTYRGLGYSLEDFND"
     gene            759..2153
                     /locus_tag="PC366_003611"
     CDS             759..2153
                     /locus_tag="PC366_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2579091.1"
                     /translation="MTKLNKKLSISISIVVVVVYIISIIINSMFIHRYYLHEKRNILD
                     NVENEIKDKDIDKLKSDITLIEEKNNIDIVYIELDKNHKDKGNIDKINQDLLNAFWKK
                     GLSLNKFWIEENSLNNIDKKSINKIYNQGKTKYSLLVKFIKKDNYLFAISIPIEHSEE
                     TIGIVNRFNIIMGIFSVVIITILTFILSNRVIKPMERLKFLSKDISELNFRTEDIKTN
                     DEIEELAYSINIMSEKLEKAHNELNKRNENLKTFISDASHEMKTPIALIKAYAIGMKD
                     GLDDGTYTDTIIEQAENMTNTINSLLYWAKYEKKERSLCLVDLKERLYKSLKNYELLI
                     ERGSISVKCSVDDKELIISSDEDSIDMVFNNLISNAIKYTNNNEIEINLFEENERIIL
                     SIKNGIDYNMGDDIENMWKPFYVLEKSRSKELSGTGLGLTIVRTILEENNFRYRVEIC
                     DGIIEFYIIFIKVI"
     gene            2578..>4504
                     /locus_tag="PC366_003612"
     CDS             2578..>4504
                     /locus_tag="PC366_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HDF2579092.1"
                     /translation="MKIPKKIAAMLTVTMIAGSSTAGIASAQTVATNLTGQERYETAV
                     KISQDGWKNADEVVIVNDSSIADALSATPFAKAKNAPILLTSKDKLNDKTKAEIQRLK
                     AKKVYLIGGTSVLSTNIEKEIKDLKISFERISGAERYQTSLELAKKLDAISDVKKIAV
                     VNGEKGLADAVSVGAPAAQNNMPVILADSKNGTAVADKFIKDAGITQSYVVGGESSIS
                     EAVKNKLPNSTRLGGTDRNDTNAKVIKEFYKKTDLKNAYVTKDGMNKQDQLIDALAVG
                     VLGAKNQSPVVLVGKNLSASQKSLVNSKSFDKITKVGGNGNETAFNEMKSLQEVKTVE
                     AKTISELKSAIDKATANDVINFKPTSEVKEAFTIQTDKAITVNLNGTYTKTVTINMPN
                     GDVNNYAKVDDVVIDDVKDGTFVNYGKITNLKVNDKNGAKIENNSKGEIGSLTVASGA
                     SQVKVTNGGKITTVTNNSKGTTIDNKGTISSVKGDNSPTISGNSPSSNSSGGSSSSGG
                     SSHGGGSSSSKVDKVVLKNTITAANKLYNEAIEGTNVGEYKVGSKAIYKTAIDKAQAI
                     LDKSGVTQKEVNDAVTALNTATDTFKAGKVVAVDKTALQDAVTAATALHAKATEGTAE
                     GNYAVGSKATYKTAIDEA"
BASE COUNT         1966 a          441 c          790 g         1307 t
ORIGIN      
        1 tataatatat aactaatgta ttataaatag ttgtaaactt cctgtaacat atattttata
       61 taattaaagt aatggatata atatgaaata taataatgaa ttttagggat gtgaataaat
      121 gaacatatta attgctgatg atgaaattag tatgcttaag atactttgtg catattttaa
      181 aaaagaaaac ttcaatgtgt ttactgcaaa aaatggggaa gaggctttag atatttttta
      241 tgaaaataag atagacttag ctatattaga ctggatgatg ccaataattg atggaataga
      301 ggtttgtaaa gagataaagg aaaatagtaa tacaagggta cttatgttga ctgccaaaag
      361 tcaaagtgaa gatgaaatag aagcactcaa cattggagca gatgaatata taaaaaaacc
      421 atttgatcct agagttttaa taataagagc taagaaacta ataaattata aaaatacaat
      481 taatattaaa gatttaaaaa tagattttgg gtcaagtaaa gtttttaaag gtgataagga
      541 attattattg actaagaaag aattagaatt aattcgttgt ttaatcaata ataaaggaat
      601 ggttttatct agggaaaaac ttttagattt agtatgggga ttggattatg agggagattt
      661 tagaacagta gatactcata taagaagatt aagggtaaaa ataggagaag atataataaa
      721 aacttataga ggattagggt atagtctgga ggattttaat gactaaacta aacaaaaaat
      781 tgtccataag tatatctata gtagttgtag ttgtttatat aatatctata attataaata
      841 gtatgtttat tcatagatat tatttacatg aaaaaagaaa tatattggat aatgttgaaa
      901 atgaaattaa agataaagac atagataaat taaaatcaga cattacttta attgaagaaa
      961 aaaataatat agatatcgta tatatagaat tagataaaaa tcataaagat aaaggtaata
     1021 tagataaaat aaatcaagat ttattaaatg cattttggaa aaaaggttta agtttaaata
     1081 agttttggat tgaagaaaat agtttaaata atattgataa gaaaagtata aataagatat
     1141 acaatcaagg taaaacaaaa tatagtttgc ttgtaaaatt tatcaagaag gataattatt
     1201 tgtttgctat atctatacct atagaacatt ctgaagaaac tattggcatt gtaaatagat
     1261 ttaatataat aatgggaatt ttttcagtag ttataataac tatacttaca tttatattat
     1321 caaacagagt tataaaacct atggaaaggt taaagttttt atctaaagat atatctgaat
     1381 taaattttag gactgaagat ataaaaacga acgatgaaat agaagagcta gcttacagca
     1441 taaacataat gagcgaaaaa cttgaaaaag cacataatga attgaataaa agaaatgaga
     1501 atctaaaaac ttttatatca gatgcatctc atgaaatgaa aactccaata gcacttataa
     1561 aagcatatgc aataggtatg aaagatggtt tggatgatgg gacttataca gatacaataa
     1621 ttgaacaagc agaaaatatg accaatacaa taaattctct tttatattgg gcaaaatatg
     1681 agaagaagga gagaagtctg tgtctggtag atttaaagga aaggttatat aaaagtttaa
     1741 aaaactatga gctgttgata gaaagaggta gtataagtgt taaatgcagt gtagatgata
     1801 aagaacttat aataagttcg gatgaagata gtatagatat ggtatttaat aatttgatta
     1861 gtaatgctat aaagtatact aataataatg aaatagagat taatcttttt gaagagaatg
     1921 agagaattat attatccata aaaaatggta tagattacaa tatgggagat gatatagaaa
     1981 atatgtggaa gcctttttat gttttagaga agtcgagaag taaggagctt tctggtactg
     2041 gtcttggtct taccatagtt agaactatac ttgaagaaaa taattttaga tacagggttg
     2101 aaatttgcga tggaattata gaattttata ttatctttat aaaagtaatt tgaattaaaa
     2161 tgtaaatata aagaataatt aaaaaaatat cgcaattatt tgtttttcat atggataaaa
     2221 ttggttattt aatatataat tacaagtata aataataaaa tttatttgta aaaagagtag
     2281 cacttttaat tctaaaggct acttttttta tacaaaacca tgttttttat aacaattcat
     2341 taacataaaa atcaaactta ccttaaaata taaatttaca aatttttcaa tcaataagaa
     2401 aatttctcta ttccttacat aatgactgta atgtaacaaa ataattacaa attaattatg
     2461 aaatcattat agttagaaac ctctttaaaa ttagatatta agtatccttt agaattagaa
     2521 cgggaacaaa gttaaaaaat taagtaatat caaatggaca agggggaaga aaataaaatg
     2581 aaaataccaa agaagattgc tgcaatgctt acagttacaa tgatagctgg aagttcaaca
     2641 gcaggcatag ctagtgcaca aactgtggca acaaatttaa cagggcaaga aagatatgaa
     2701 actgctgtta aaataagtca agatggatgg aaaaatgctg atgaggtagt aatcgtaaac
     2761 gactcatcta tagcagatgc tctatctgca acaccatttg caaaagcaaa aaatgctcca
     2821 atacttttaa caagtaaaga taaattaaat gataagacga aagcagaaat acaaagatta
     2881 aaagctaaaa aagtatactt aataggtgga acttctgtat taagtacaaa tatagaaaaa
     2941 gaaataaaag atttaaaaat atcttttgag agaatctctg gagctgagag atatcaaaca
     3001 tccttagaat tagcaaagaa attagatgct ataagtgatg ttaagaaaat agctgtagtt
     3061 aatggtgaaa aaggacttgc agatgctgta agtgtaggag caccagctgc acaaaacaat
     3121 atgccagtaa tacttgctga ttctaaaaat ggaacagcag ttgcagacaa atttataaaa
     3181 gatgctggaa taactcaatc ttatgtagta ggtggagaga gttcaatttc tgaagctgtt
     3241 aaaaataaac taccaaatag tacaagacta ggtggaacag atagaaatga tacaaatgca
     3301 aaagtaataa aagaatttta taaaaagaca gatttaaaaa atgcttatgt aactaaagat
     3361 ggtatgaata aacaagacca acttatagat gcactagcag taggtgtatt aggtgctaaa
     3421 aatcaatcac cagtagtttt agttggaaag aacttatcag cttcacaaaa atctctagtt
     3481 aactctaaga gttttgataa gataactaaa gttggtggga atggtaatga gacagcattt
     3541 aatgaaatga agtcattaca agaagtaaaa acagttgaag ctaaaacaat ttctgaatta
     3601 aaatcagcta tagataaagc tactgctaat gatgttataa actttaagcc aactagtgag
     3661 gttaaagaag catttacaat acaaactgat aaggcgataa cagtaaactt aaatggtaca
     3721 tatacaaaga ctgtgactat caacatgcct aatggtgatg taaataacta tgcaaaagtg
     3781 gatgatgtag ttatagatga tgtaaaagat ggaacttttg ttaactacgg aaaaataact
     3841 aacttaaagg ttaatgataa aaatggagcc aagatagaaa ataattctaa aggtgagatt
     3901 ggtagtttaa cagtagcatc tggagcaagt caagtaaaag tgactaatgg tggtaagata
     3961 actacagtta caaataattc taaaggaact actatagata ataaaggtac aataagtagt
     4021 gttaagggag ataattctcc aacaataagt ggaaatagtc caagttctaa ctcttcagga
     4081 ggaagttcat caagtggagg ttcttcacat ggaggaggaa gttcttcatc aaaagtagat
     4141 aaagtagttt tgaaaaatac aataacagca gcaaataaat tgtataatga agcaatagag
     4201 ggaacaaatg taggtgaata taaagtaggg tcaaaagcaa tatataaaac agcaatagac
     4261 aaagcacagg caatattaga caaatctggt gtaacacaaa aagaagtaaa tgatgcagta
     4321 acagcattaa acacagcaac agacacattt aaagcaggaa aagtagtagc agtagataaa
     4381 acagcattac aagatgcagt aacagcagca acagcattac atgctaaagc aacagaagga
     4441 acagcagaag gaaactatgc tgtaggatca aaagcaacgt ataaaacagc aatagatgaa
     4501 gcac
//
LOCUS       DAMJWO010000161         4500 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.167, whole genome shotgun sequence.
ACCESSION   DAMJWO010000161 DAMJWO010000000
VERSION     DAMJWO010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4500
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.167"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(97..642)
                     /locus_tag="PC366_003613"
     CDS             complement(97..642)
                     /locus_tag="PC366_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HDF2579093.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(760..2583)
                     /locus_tag="PC366_003614"
     CDS             complement(760..2583)
                     /locus_tag="PC366_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2579094.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVKEMRSNLFLKFKNLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPIVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYERKSVNDFKEVNDRLLNISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGVLASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEQEEQEVHNMFKSEINDNKDGNLNSHFVKGEIELKDVSFSYDSKKKILDNINLKI
                     KAGTSNAIIGETGSGKTTIINLITNFYHIDEGSIFLDGKDIYSINRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANAHKFIVKMREGYSTVLSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            complement(2596..4371)
                     /locus_tag="PC366_003615"
     CDS             complement(2596..4371)
                     /locus_tag="PC366_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2579095.1"
                     /translation="MKYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGAIMIGITFLGAIFAIIRSVISARVSQHFSYDLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKIGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENQSF
                     EELNDELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRHLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLVDENEEVIEREESLDVGEKDLKFV
                     NCDIIFENVDFSYNKNTDEKILKNVSFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGRSIYSISEESLREKIGVVFQNSSVFGKSILENIVMGNEGISREDVIKSC
                     EIANANQFITKLENSYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKEYISNLREKESKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFALQNLVSEDVN"
BASE COUNT         1471 a          798 c          395 g         1836 t
ORIGIN      
        1 aaatataaaa tacaactatt aaaaaggagc atatcattat aattttaaaa atcataaatg
       61 atatactcct aaaaatctac ttaacttata ttaaatttat tttccaaaat atctatttaa
      121 taatcctaag aatgctttac catgtctagc ttcatcttta cacatttcat gtactgtatc
      181 gtgtatagca tctagtccta attctttagc ttttttagct aattttaatt ttccatcagt
      241 tgcaccatac tcagcatcaa ctctaactct taagttttct tttgtatctg caactacaac
      301 ttctccaaga agttctgcaa atttagcagc atgttcagct tcttcaagag ctattctctt
      361 ataagcttct cctacttctg gataaccttc tctatcagct tgtctactca ttgctaaata
      421 cattcctact tctgtacact caccaacaaa gttagctctt aatccttcga ttatttcttc
      481 atctacacct tgagctactc ctattctgtg ctcatcagcc caattttttt cgcctttcat
      541 ttcttcaaat ttatcagctc caactttaca tactggacat tgtgctggtg cagcatctcc
      601 ttcatgtata tatccacata ctgtacaaac aaatttcttc ataattactt tcctcctaaa
      661 ttttatatat caaattaaat tttttattta ttaagttagt ctatatatac ccgcaccata
      721 tacctttaaa caattttttt aaaagttttt tctaaatact tattttccct gtgtcaataa
      781 tatgtttcta taataatgtc cctttaattt tatcaattct ttatgatttc ctgattccac
      841 aattctacca ttttctaaaa ctattatatt atcacaattt gatatggtac ttaatctatg
      901 agctataatt atacttgtct ttccataagt taaattattt attgcttctt gaattttagc
      961 ttctgttgct atatctatgt tacttgtagc ctcatccaaa ataagtattg gagcattttt
     1021 taatactgct ctagcaatac ttattaattg tttttgacct tcacttaaat cttcacccct
     1081 atccgataat acagtactat atccttcacg cattttaact ataaatttat gtgcatttgc
     1141 tattttacta gcatatataa cttcttcatc agtagcctcc agatttccat accttatatt
     1201 ttccataact gtatcattga atatataacc ttcttgtgga actactccaa aacaagttct
     1261 caaatagttt ctgttaatag agtatatatc cttaccatct aaaaatatac ttccttcatc
     1321 tatatgataa aaatttgtaa ttagatttat aatcgttgtt tttccacttc ctgtctctcc
     1381 tatgatggca tttgatgtgc cagctttgat ttttaggttt atattatcta aaattttctt
     1441 ttttgaatca taagaaaaac ttacatcttt aagctcaatt tctcccttta caaaatgaga
     1501 gtttaaatta ccatctttat tatcgttaat ctcactttta aacatgttat gcacttcttg
     1561 ctcttcttgt tcatctataa tttcaaaaac tctttcacat ccagctatgg ctgaaagtaa
     1621 tgtattaaat agatttgcta attcatttaa aggtcttgtg aattgtctta cataacttaa
     1681 aaaactagct ataaccccta tggttataat atctttagat gcaagaacac ctcctataat
     1741 acatatagtt gcaaatccta tattactaat cacattcata ataggcatta aaagagaagt
     1801 gtaaatttgc gatttaaggg aaatatttag aagtctatca ttgacttctt taaaatcatt
     1861 tacagatttt ctttcataat taaaagattt tactacattt atgtttgata tcatttcttc
     1921 aatatgtgca tttagttttc ccaactcaac ttgttgttgc ttaaaaaaaa ctctagttct
     1981 ctttgcaata aaattactca caaacattac tatcggtatt aatattacac tgcaaaatgt
     2041 taaaattggg cttaatacaa acatcataat aaaagtcatc aatatgttta agattcctgt
     2101 aattaactgt actaatgaat ttgatattcc tgtactgata ttatcaacat catttgtcac
     2161 tctactcata atatctccag tagaactttt atcaaaaaag gttattggta gatttttaaa
     2221 ttttaaaaat aaattacttc tcatttcttt aactatactt tgagataatc tagctgtaca
     2281 tatcccctta gacagtttaa ctgaaaactc aattatataa aatgaaagta aaataattat
     2341 tccttttaag aaaatggatt ttgaataagt atcgatatct attatgtcaa ctacctttcc
     2401 aatagtatat ggtattacag ttgatataat tgaatcaatt attactagca aaaaaataaa
     2461 tctagtaatc ttcttatctt ttttaaagta cataaaaatt cttttaaacg tttttttaaa
     2521 atctttaggc ttttcttttt tctttaatct actgaccttt tgatttccag tacttaagtt
     2581 caatatactt cctccttaat ttacatcttc acttactaaa ttctgcaacg caaaaatttt
     2641 tttataaatt ggagaactaa ccagtaaatc ttcatgtgta gcaaatccaa ccacctcacc
     2701 ctcatccaag actaaaatct tatcacagtc aattatagaa ctaatctttt gtgaaatagt
     2761 tattacagta catttcttac tttccttttc tcttaaatta cttatatact cttttatatt
     2821 ctttcttata attgtctctg tattaatatc cattgcacta aaacaatcat caagaattaa
     2881 tatttgtggt tttttggcta tagctctagc tatagtaatt ctttgtctct gtcctcctga
     2941 taaattttta cccctttgaa ataaaacctc atcataagaa ttttcgagtt tagttataaa
     3001 ttgatttgca tttgctatct cacatgattt tataacatct tctctactta taccctcatt
     3061 tcccataact atattttcta gtatactttt tccaaacaca ctgctatttt gaaatactac
     3121 acctattttt tcccttaaac tttcttcaga aatactgtat atactacgtc ctccaatctt
     3181 aatatcacct ttatcaatta tatataattt ttgaattaaa tttactaaag aagtctttcc
     3241 tgaaccagtt tgaccaatca caccaatatt ttgaccttct tctattttaa aggatacgtt
     3301 ttttaatatt ttttcatctg tatttttgtt atacgaaaaa tctacatttt caaaaattat
     3361 atcacaattt acaaacttta aatctttttc tccaacatct aaactttctt ctctctcaat
     3421 tacttcttca ttctcatcaa ccaaaacctc acttattctc tcataagatg cttttgccct
     3481 aacaaaaaca ttaaaaacat gtgaaatcat tataagagat gttaatattc tagtcatata
     3541 gtttacataa gcaactataa tcccaatttt aatttctcct gaataaatta aatgccttcc
     3601 aatcagtaat attattatta tggaaacatt aatgattatt gtaattgtcg gtctaaaaaa
     3661 tgacatcata gttgtagctt ttctactatt tttaaaaagt tcatcattta actcttcaaa
     3721 gctttggttc tcataatcgt atctacaaaa tagtttaact acttttattc cacttaaaaa
     3781 ctgtcttaat tttgaattta ctttatctgt actttcttgt acatttttaa ataatctata
     3841 ccctatcttc atattaagca atattataat aaatataatt aaaactgcaa ttagaataat
     3901 tattgacatc tttaaattta attttatagc tataattaaa cttcctatac acattattgg
     3961 tgactttata aaaactctca tcattccatt aacgaattgt tgcatttgat tgatatcatt
     4021 agtaattctt gttattaacg aagctctacc aaatttatct atttgtttta atgagtatgt
     4081 atttatcttt tcaaatacat cctgtcttaa atcataagaa aaatgctgag aaactcttgc
     4141 cgagattaca cttcttatta ttgcaaatat tgcacctaaa aaagttatac ctatcattat
     4201 agctcctgtt gatagtatgt agtctaggtt cttatttgaa acccctatat ctattatttt
     4261 tgccattata gttggttgag ctaaatcaca aaaagcttcc aatgttaaaa aaaatactgc
     4321 tgttagaaat aatactatat atttttttat gtatttttta aaatacttca ttcaatcatc
     4381 ccttcataga attttctcat taccaaaagt atatcataat ggctaattta attgattata
     4441 tcaattataa atatttgatt tattattaat ttttatacca tatattttat aaattatttg
//
LOCUS       DAMJWO010000162         4341 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.168, whole genome shotgun sequence.
ACCESSION   DAMJWO010000162 DAMJWO010000000
VERSION     DAMJWO010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4341
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.168"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            284..622
                     /locus_tag="PC366_003616"
     CDS             284..622
                     /locus_tag="PC366_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2579096.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
     gene            644..961
                     /locus_tag="PC366_003617"
     CDS             644..961
                     /locus_tag="PC366_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2579097.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            1111..1788
                     /locus_tag="PC366_003618"
     CDS             1111..1788
                     /locus_tag="PC366_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579098.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(2116..2883)
                     /locus_tag="PC366_003619"
     CDS             complement(2116..2883)
                     /locus_tag="PC366_003619"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDF2579099.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKVAVMPQNERDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            3689..4321
                     /locus_tag="PC366_003620"
     CDS             3689..4321
                     /locus_tag="PC366_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HDF2579100.1"
                     /translation="MTIPNSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVSPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
BASE COUNT         1756 a          537 c          533 g         1515 t
ORIGIN      
        1 tattctacat atctaatatg taattacaat aaaaaatgct ataattaaca tattattaat
       61 tcgttttatt attgtagtat ggctatgaaa ttatgaaaat atttctctaa ttaaaaatat
      121 gatttatcca tatttgttta ttgtagatac agactataca aaaataaata gcacttattt
      181 cagtataaaa acatatatag tctatattta gactaaaaaa gtataaatag tctatataaa
      241 acaacttaaa ctatgaatat aatctaaagt ggagggataa taattggcaa atataggaaa
      301 aataatagga gatagaataa aagtctatag aacaaaattg ggatatagtc aagagtttct
      361 agcagaaaag gcaggtttac atccaacata tattggtcag attgaaagag ctgagacaaa
      421 tacatctatc aatattataa tgaaaattgc tactgcttta gacataccac ttgaattgtt
      481 atttgcaaat attattacaa cagaaggcgt tgataactct gtacctttag aatgttatga
      541 aatgattaat aaattaactg aaaaagaaca aattgcaatg ctagagttaa taaagtgcat
      601 cattaaatac aaagaaatat aagtgaggga aatagtaaca ataatgaatt atataggtaa
      661 aagacttaaa gaagaacgaa aaaaagcaaa tttaacttca aaagaatttg caaatatggt
      721 tggagtatcg ccttggtata taactcaaat cgaaagtggt aaaaagaatc caagtcttaa
      781 aacattcata aaatttgtaa atatattaaa tatttctgca gatgttctta taaaagatat
      841 tacttccact ggaaaaacat atttagaaaa tgatataaat gaagagttaa aagacttaaa
      901 ttcaagagaa ctaaatctga tatcacagat tatagacatc ataaaaaaga ataaaatata
      961 attctttata ttttatataa aaaaaaaggt tatttgaaat aaataacctt tttttgtctt
     1021 tttgtgttaa cattgtctta tagtgctaat gagtactatt agaccatgtt ctatggcctt
     1081 attttaatat aaaacgattg gagataggct atgattgtga ttgaaggtag tgataaattt
     1141 aagattgcaa aagaatatat tgatgtagaa tatactcttt ttagcaaagt aacttttagg
     1201 tatgaaaagt tgaaatttaa agataatgct gaattggaaa aaattaagat gtttaaatat
     1261 aaaaatggct acatccctaa taaattaaac ctttcttttg gatatggatt ctcttcttat
     1321 aaaaagcaaa taattagaga aactgtagat actttaagat tgacagaaat tttttcaagc
     1381 gagaacatag aagatattaa atttataaaa gatggtacaa aaaaattaga aattagcata
     1441 gagaaagttg tgaaatttaa acgtcgaaaa aaaagaaatt atgtttgttg ctattgccct
     1501 gatatgtata gagatataaa actcgacaaa gaatctatca ataagatata caacagaaaa
     1561 ataaaaatag aaagagaagt taatattttt gaagatgagg atgttataat aaacaagaaa
     1621 gtattgaagt ttccaaagtc ttggacaaag aatatgcaaa aatattggtt aagtgaaaat
     1681 aagtatccca tacattctac tgtaattgat gatgatagat ataaatgttg taatgtacaa
     1741 tatacaaaaa atagagtgat aatattatat tacatatata accattaata tacataatta
     1801 caaaaaaata atgacaaata tacataatac aaatatatct tctactttag ataaaacagt
     1861 tattatgaaa acttactatc tataaataat agaaatgcta gtataccatc tataatctaa
     1921 tgtctagtag gttttaatgg catattttaa atatgccata gttgatttat aagattttct
     1981 atatcacttt caaaatacac actaaatagt tgcttttcag atataattgc ccaatttaaa
     2041 ttttactatc tgaaaagttt tttatattta atttatatct tcaaaaatac cgtctaatat
     2101 ttctatataa ttaatttaat taatactctt atgtaataga ttaagtactg aatttaactc
     2161 tttaaatgat atttgccctg gtgctgaaac actttttgca gctccaaaag tcaatgcaga
     2221 accaaatatt tcaccacaca atctacttat aacacccatt cctgacattg acattgttat
     2281 tattggtcta tctgcataaa ttttaaacat ttcatttgta gcttcaagta gcactaacac
     2341 atctctttca ttttgcggca taacagctac tttgggtaaa tctgcgccca attcctgcat
     2401 tctacataaa cgagatacaa tctcttcttt ttttggagtt ttattaaaat catgattaga
     2461 tataattact ttcacttctt ttttatgagc aaaattaact acttcatcta tgacctcatc
     2521 tcccataaat aactctacat ctattaaatc tactaaacct gtattagaaa tttctttatt
     2581 caaagtagta taataatctc ttgatattaa tttttctccc ccttctacta cacttctaaa
     2641 tgtgaataat aaagggatat catgtatata acttcttaat tcatagagaa cttccttaac
     2701 ttctttaata ttttctacat tctcaaaaaa atcaactcgc cactctataa tatccaaaca
     2761 tgcatctttt aactctttag cctcttttat aatatctttt ttatttttcc caataattgg
     2821 tacacaaatt ttaggtctac cttctccaat agtaatattt tttacttgaa cttttctttt
     2881 catattctcc tccataatca gaaattctat aggactttaa attctatttt ctgcataatt
     2941 taattataca ttaaaaatac tatacattat aaaaatacta atttaaaaat aatttttatt
     3001 ctaattctta aaacaatccc acatatttta gaaaaggtac tctataatat acaaacactt
     3061 cttttttacc taaatttatt ttaacattct ataattttca caatattctt taaattttac
     3121 tcatataaac aatattattc tggatgctaa tagaattaat ctataaatca tagtataatt
     3181 atgcagaaat aactcgaatt tcactactta taaagagatt gaatattaat gaatctaaat
     3241 catttgcatt acttcagagt tttgactaaa gttgaacacc atacaaaagt agctactcaa
     3301 ttgtttatac cccaaccaag cttaagtaat gttatataga ttcttgaaaa agaatttggt
     3361 atctttttat ttgaaaaaca aggtagaaat gtttccctca ctaaatacgg aagttttttt
     3421 ctaacctatg ttgataaagc attaggttaa ttagaaaaag tttacatata aaatatatta
     3481 aattgttgca agttttattg ttttgatata caatcaacta aacatataat ctttataaaa
     3541 tactatacag ttaaaagtct gttttaaaaa aaaatgtata aattataaat caaaatatag
     3601 atactatcaa ggagtgattc tgtgaagaga tgtattgtag tagtggaata gtcaaaaaca
     3661 taatatatat taaaggagag atttaaatat gactattcca aattcaaata aggtatatcc
     3721 aagaagtaat gattatcaaa ctgtatatct taaaaatgta ataacaaggg aaaatataga
     3781 agttggagat tacacaatat ataatgactt ttataatgac ccaagagatt ttgagaaaaa
     3841 caatgtatta tatcattacc ctataaacaa tgataaatta ataattggta agttttgctc
     3901 aatagcatgt aatgcaaaat ttctaatgac tagtggaaat cactcaatga aatcaaaatc
     3961 cacatatact tttcccatct tttatgaaga atggaaactc gatatcaacc atataacgga
     4021 cgcttgggac aataagggta acattataat tggaaatgat gtgtggatag gttatgattc
     4081 tataattatg tcaggtgtaa atattggtga tggtgcaatt attggaacaa gagcagtagt
     4141 tactaatgac gtctcaccgt attctattgt tggaggagta cctgcaaaaa ttataaaaaa
     4201 gagatttaat aatgatacaa tttcaaaatt attagaaatt aaatggtggg attggccata
     4261 taaaaaaatt caatcaaaca ttaagcatat tcaatcagga aatattgata aattagttta
     4321 atattttata atttatttat a
//
LOCUS       DAMJWO010000163         4215 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.169, whole genome shotgun sequence.
ACCESSION   DAMJWO010000163 DAMJWO010000000
VERSION     DAMJWO010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4215
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.169"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            64..600
                     /locus_tag="PC366_003621"
     CDS             64..600
                     /locus_tag="PC366_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HDF2579101.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            632..1021
                     /locus_tag="PC366_003622"
     CDS             632..1021
                     /locus_tag="PC366_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF2579102.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            1058..1444
                     /locus_tag="PC366_003623"
     CDS             1058..1444
                     /locus_tag="PC366_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HDF2579103.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGSQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            1571..3013
                     /locus_tag="PC366_003624"
     CDS             1571..3013
                     /locus_tag="PC366_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF2579104.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVENESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLIDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            3310..4125
                     /locus_tag="PC366_003625"
     CDS             3310..4125
                     /locus_tag="PC366_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2579105.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINNFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKRVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEIRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
BASE COUNT         1619 a          444 c          811 g         1341 t
ORIGIN      
        1 tgatataata tataaatata gaaatagtaa tcattactat tattaaaaag ggaggaatta
       61 attatgaact taaaaggaac taaaacagaa aagaatttaa tggcaggatt tgcaggagag
      121 tcagaagcaa gaaataaata tacatactac gcttcaaaag caagaaaaga aggttataat
      181 caaatagctg ctatatttga agaaactgct aacaatgaaa aggaacatgc taaattatgg
      241 tttaaacttt tacatgatgg tatgccttca acagaggaaa atttaaagga tgcagcagca
      301 ggtgaaaact atgaatggac tgatatgtat gcaaaatttg ctaaagaagc tagagaagaa
      361 ggatttgaca agatagctta tttatttgaa gctgttggaa aaatagagaa agagcatgaa
      421 gaaagatact taaagctttt agaaaactta aatgaaggaa aaatatttaa aagagatgaa
      481 gaagttgttt ggcaatgtca aaactgtggt catgtgtatg taggtactga agcaccagaa
      541 aaatgcccag tatgtgacca tccaaaagcg tatttcaata taaaagctga aaattattaa
      601 aaattatcat tattaaaaag gaatgttaac tatgaaattt tctaaacaac gagaactgat
      661 tttaaatgaa atattaaata atccggttca tcctactgcg gattacctat atgaaaactt
      721 aaaaaaagat aatccaaatt taagcttagg aactgtttat agaaatttag ctcagctaac
      781 ggaacatggc tttataagaa aggttagtat tccagggtat ccagatagat ttgatggtcg
      841 aatagataat cactatcata tcatatgtga agtatgtgga gaggtatacg atttagaatc
      901 cgaagttctt aataatttac aagaattaat atctgaggag acagacataa aaataacatc
      961 ttataacata agttttaaag ggatttgtaa taattgtaaa aggtgtagcc aagtaggtta
     1021 gttttcaaat tctaaaaata attaatgagg tgagtttatg tgtagtgaac aaaaattttt
     1081 tatatgtgag acttgtggaa accttgtagg aatgatacaa agtggtggtg tacctatttt
     1141 ctgttgtgga aaacctatga aggaacttgt tcctaataca acagatgcag cagttgaaaa
     1201 acatgtacct gtaattgaag tggatggaaa taatgttact gttaaagtaa gtagcacaac
     1261 tcatccaatg actaaagaac atcatatagc atgggtgtat cttatgactg aacaaggtag
     1321 tcaacgcaaa tgtctagcag tagatggaga acctgtagtt aaatttgctt tgaatgatga
     1381 tgataaagtg atttctgcct atgcttactg taatttacat ggattatgga aggctgaact
     1441 gtaatattta aataaattga gtcaaagagg aggctataaa tgtattttca tacaaatagc
     1501 ctcctataaa tttatataaa ttcaagtttt aattttgttt aatgtcaata taatataagg
     1561 agaaaataat atgtcaattt ataaatgtag tgtttgtgga tatatttatg atgaatctaa
     1621 gaatgataaa acatgggatg aattaagtga agattgggaa tgccctgtat gtacaaaagg
     1681 tcgtagttat tttggaaaga taagcactgt ttactatgaa gaagatgaaa agatagcaga
     1741 agacatagtt gaaaatgaat ctaaattaaa tactgaaaaa gagggagatt taaattactt
     1801 aagtacatat ttaagaagag atgatgaagt tgagaaacat atggatataa ttcacgaaat
     1861 ggctgttaca ggaaaatcta taatagaacc tatgagaact aaactaccag taatttcttg
     1921 ggatgatatt ttaattatgg gtgctcaatt aaatccatta cctttaaatg agcatgatga
     1981 agtaaataca acaacaataa taggaaaaaa agcaaagaaa cctatgatta tagaaaatcc
     2041 agtttatatt tcccacatgt catttggagc tttgtctaaa gaactaaaaa tagctttagc
     2101 aaagggtgca gcccaaaata agacagctat gtgtagtggt gaaggaggta tattaccaga
     2161 agagaaggaa gcttcataca agtatatttt tgagtatgta ccaaataaat atagtgtaac
     2221 tgaagaaaat cttaaaaatt ctgatgctat agagataaaa attggtcaag gaacaaaacc
     2281 tggtatggga ggtcatcttc ctggcgaaaa agtaactgaa gaaatagcaa aagtaagaaa
     2341 taagcctgta ggtcaagatg taataagtcc atcttgtttt gaggaaatac aatccaaaga
     2401 ggatttaaag aaacttatag atgaacttag agaagtttca gaagggcgtc caataggtgt
     2461 taaaatttca gcaggtcata ttgaaaaaga tatggaattt atagcttatg ctaaacctga
     2521 ttttgtaact attgatggtc gtggtggagc tactggagca agtccaaagt tgcttaaaga
     2581 tgcaacttca attccaacaa tatttgctct ttatcgtgct agaaaataca tagatacaca
     2641 tggattagat atagatttgg ttataacagg tgggcttcgt atatctactg attttgctaa
     2701 ggcaattgct atgggggctg atgcagttgc tattgcaagt tctgctctta tggcagcggc
     2761 gtgtcaacaa tatcgtatat gtggttctgg taagtgtcct gtaggagtag ctactcagga
     2821 tgaggaattg agaaaaagat tacatataga aaatagtgct aatagagtgg caaacttttt
     2881 aaatgtaagt ttagaagaac ttaagacttt tgctagaatt tctggtcata aagatataca
     2941 tgatttaagt gttgatgatt tatatactgt taactctgaa atatcaaatt atacaaacat
     3001 acagcatgta tagattgaag tttgaaacta ttagatttta gatagctata aaagtaaatg
     3061 ataaatatat tttataaaag agagtgtctt aaaatgaact ttttagttca taagtcactc
     3121 ttttttgtat gaagccaaat atatttatca ttttagcaat gaaaaagaat cttatctctt
     3181 tattttgaga tagactcctt ctatttatga aaattaaaga tattaaattg taaaatattc
     3241 tgtgatgtcg tactattaaa ctaaagattc tgtactttaa agtaaataaa aatttaagga
     3301 gtgcttatta tggaaagatt gaagatacaa gttttagttg acaataatac ttatattgat
     3361 agatactttg ttggagaacc agcagtaagc tattatattg agattgatgg aaataggatt
     3421 ttgtttgatt cgggatattc agatgtattc atatcaaacg ctgaaaaatt aaatatagat
     3481 ttaggaaatt taactcatgt tgttttttct catggacata atgaccatac aagaggtatc
     3541 cagtttttag aaaataggta tgatttatct acagttgaac ttatttcaca tcctaactgt
     3601 tttataccta gaaaacatgg agagaaaagc ataggagctc cattttctgc tgaggaaatt
     3661 aaaaatattt ttatgtataa tcctaaggat aagccattta atctaagtaa gaattgtgtg
     3721 tttttaggtg aaataccttc tataaataat tttgaaaaaa gagctaaaat tggtaaatgt
     3781 aaaataggag atttgtggga agatgattat gttttagatg attctgctat agtttgtaaa
     3841 actgataaag gtatttttat tgttacagga tgttctcata gtggaatttg taatatagta
     3901 gagtatgcta aaagggtatg tggagatgat agagttattg gtatactagg tggttttcat
     3961 ctttttgaat tgaataatag gttagatagt acaatacaat atttggataa agaagaaata
     4021 agaatgttgt acccttgtca ctgtgtttct tttaaggtaa aagctaagat gaatgaaata
     4081 ttgaatataa atgaagttgg agtagggctg accataagta tatagtattt gaaagtatat
     4141 aagatttaag ttgaaggtta aaaagatatt ttctatataa agtatctttt ttgttacgtt
     4201 tattttaaga gaaat
//
LOCUS       DAMJWO010000164         4003 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.170, whole genome shotgun sequence.
ACCESSION   DAMJWO010000164 DAMJWO010000000
VERSION     DAMJWO010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4003
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.170"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(220..1470)
                     /locus_tag="PC366_003626"
     CDS             complement(220..1470)
                     /locus_tag="PC366_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HDF2579106.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLYEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRVIDDI
                     INDFMDNNEPLYDFITDDKIEHTVWKIDSDDIIDNLVDKFEKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLGDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1502..2443)
                     /locus_tag="PC366_003627"
     CDS             complement(1502..2443)
                     /locus_tag="PC366_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HDF2579107.1"
                     /translation="MYNILVTDGIEKEAARKLRELDFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLENADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
     gene            complement(2683..3759)
                     /locus_tag="PC366_003628"
     CDS             complement(2683..3759)
                     /locus_tag="PC366_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HDF2579108.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASMLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYEDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
BASE COUNT         1205 a          728 c          424 g         1646 t
ORIGIN      
        1 atatttaaaa ccttataaat atacaaatac aattatatga attttcatcc tcaattatag
       61 catagaatat gactatctat atcctaaaat tatccatttc taaaaaaagg taactattat
      121 taagaatatc aacttataga atttatattc cacatacgat tttcaatcaa aaaaacaagg
      181 gctaaaaagt gaattgtaca ctttttagcc ctttattaat tattcattta tttcatgtaa
      241 gaatagccca catcttactt taggttcaaa ccatgttgac ttagctggca ttatcttatt
      301 tgcatctgct actcttatta aatcttcaat actagtagga tacattgcaa atgctacttt
      361 catatcttca ttaactcttt tttctaattc ttcaagacct ctaattccac cgataaaatc
      421 aattctttta tctactctag gattgtcaat tcctaaaata gcatcaataa catagtcttg
      481 taatatagaa atgtctaatg agtcaacagg gtcttctatt tctaataaat ttttatttgc
      541 tttcatttta taccacttat cacctaggta cattccgaaa gttccttttt tgtcaggttt
      601 atatttttct tttccttcta tttcttctag ttcaaaattt tcttttattt tatttataaa
      661 ttcttcctcg cttaaaccat ttaagtcttt gataacccta ttataatcca aaaccattaa
      721 attctcatct ggtgcaatca ttgctatgaa gtaattaaat tcttctttgc cagtataatt
      781 tggattttta gctctcattt ctttggctac attttctgct gaagctgtcc tatgatgacc
      841 atctgcaatg tatagataat ctaatttttc aaatttatct actaggttat ctattatatc
      901 atcactatca atcttccata ctgtatgctc tatcttgtca tctgttatga aatcatataa
      961 aggttcatta ttatccataa aatcattgat tatatcatct atcacccttt gatgtttgta
     1021 agttacaagt atagttcccg tattagcatc acagtatttt atgtgtttag ttctatcaat
     1081 ttccttttct ggtcgagtgt actcatgttt ttttattgtt ccattcaagc tttcatcaac
     1141 tgatatacat gctactatac caacttgagc tctaccatcc atgatttgtt tatatatata
     1201 tatacactct ttgtcatctt ttactagaat ttcttgtttt cgaaactcat ataaattttc
     1261 tcgcgctttt aaataaactt tttcatcata taaatctata ttttcatcta aatcaatttc
     1321 tgatttatct atatgcaaaa atgaatatgg attcccttct gcaattcttc tagcttcttt
     1381 actattcata acatcgtaag gaagtgctgc tactttatct actatatatt tatttggtct
     1441 aatcgcctta aatggtttaa tcgttgccat tactaatttc ctcctaatta tacaaaatat
     1501 tttataatgc tacccctatt agattgttga agtcaagaaa gaaatcttga atcacattta
     1561 ctatttcgtc tcctattctt tcttgagctt ctactgtaga tgccccaata tgaggtgtag
     1621 gagaaactct tggatgattt actaagtcta aatttaatgt aggttcttgt tcataaacat
     1681 ctatagcagc tgctgataat ttaccttcat ctaatgcttt tagtaaatct ttttcatcaa
     1741 ctaaaccgcc tcttgcacag tttattaaat aagccccttt cttcatctta tttatttctt
     1801 tttcagttat tactgccccc ttattcttat caaatggtat gtgtaaagat aagaaatctg
     1861 cattttctaa aacttcttcc atatcacaga atttataatt gttaaaacct tgcgcctcac
     1921 ccattatgtc agtatatata acattcatac ctaataattc tgctctcttt gcaacttctt
     1981 ttgcaattct tccaaaacct ataagtccaa gtgtctttcc attaatttct gtacctttat
     2041 acttcttctt ctcccatttt ccatctctca tagttacatt tgcagtattt atgaatcttg
     2101 caagaacaaa taattgacct attgtaagct ctgcaacaga tatactgctt gcatttggag
     2161 tattcataac ttttatgcca ttagcttgag catatttaac atctatatta tccagaccta
     2221 ctccacctct tactatcaac ttcaactttt taccctctaa tgctttatct attacatctt
     2281 tagtaacttt agtagctgaa cgtactacaa gtacatcaac atctttaagt ttatctccta
     2341 aaacatcttt ttcataaaac tgctctatca cattaaaatc taactctctc aattttctcg
     2401 ctgcttcttt ctctattcca tcagtaacta atatattata cataacaaac tcctccaatt
     2461 tttattcact taatttttcc aatttttatt ttttaaagta ttttcatcaa taaaaaactt
     2521 tacttaattt aactttctgt ttatataatt ttcaaaatat ttttttatta aagtcatatc
     2581 aaattttcct attgtttgtt aaaaatttaa tatgtaattt ttataaaata ttatttatta
     2641 tatattctaa atttatctta aaacatacat atttttacaa tattatttat taaaacctaa
     2701 tatatcatca atattatcta ataattcttg tacatcttcg acagtatagt cacccatatg
     2761 tgaaattcta aaagtttttt cttttaaatc tccatagcca tttgctattt ggaatcctcg
     2821 ttcttgtaat tttgaattta aatttgatac actaatacct tgagtatttt ctataacagt
     2881 aagtgtattg gataagtgat tttcattggt aaaaatttgg aagtgttttt tagcccagtt
     2941 tctaactaag tttgccatgt cttcatgtct gttgaatctg ttatctaggc cttcatctaa
     3001 tatattatct aattggaaat ctaaagcgaa catgtgagaa agagatggtg ttgaagggta
     3061 ttggtagttt ttcttgatta agtattcata cattgctaac aaatcaagat atactcctct
     3121 aaaaggtact tgcttagctc tatcgattgc tttttgagaa aatgtgcaaa tagacattcc
     3181 tggtggtaat cccagtgctt tttgtactga tgttatacaa atatctattc caatcttatc
     3241 aacctcgact tttattccac cggctgaact tacagtatct acacagtaga ttacatcttc
     3301 atacttttta acaacttctc caatttcttc tattggattt cttattccag ttgaagtttc
     3361 attgtgagtt acagttatta aatcgtattc tccggtagaa agcaccttat caaccatttc
     3421 tggcgttgtt gcctctccta attcaacttt aaatatatcc gctgggacat tattagccac
     3481 tgccattttg taccatctat caccaaagga tccacaggaa aatactgctg cctttttgga
     3541 tgtacaggaa cgaatggagc cttccattaa accagttccg gatgacgtgg ataaaagtat
     3601 cgtgttgttt gtatagaata gtttttgcat cttttcactt atactctttt ggagcataga
     3661 tgcatctttt cctctatgtc ctatcattgg tgtagccatc ttttgcaaga cttcttcttt
     3721 aacatcaata ggaccaggaa taaataattt cttactcatt ataattcccc cctttttagt
     3781 ttgtaatatg gatagcgttt ttactgtcct tatttttaat aactataata tcaagctgaa
     3841 ttaactatgt caacataaaa tttatttttt atatataatt tattttatat attttatgaa
     3901 aacattcatt ttctgccttt tcataagtct gaattttctg aattattctc tcaaaaaaaa
     3961 tatacttttt atctatataa attaattttt ttagtatgta aat
//
LOCUS       DAMJWO010000165         3939 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.171, whole genome shotgun sequence.
ACCESSION   DAMJWO010000165 DAMJWO010000000
VERSION     DAMJWO010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3939
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.171"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..239
                     /locus_tag="PC366_003629"
     CDS             <1..239
                     /locus_tag="PC366_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005209661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579109.1"
                     /translation="VEESRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKIRRTAIEF
                     STEIMTSLDTLKALVEVKKKHLNKDELKVYNIAE"
     gene            497..1546
                     /gene="carA"
                     /locus_tag="PC366_003630"
     CDS             497..1546
                     /gene="carA"
                     /locus_tag="PC366_003630"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDF2579110.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESVGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITIFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            1739..>3939
                     /gene="carB"
                     /locus_tag="PC366_003631"
     CDS             1739..>3939
                     /gene="carB"
                     /locus_tag="PC366_003631"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) large subunit"
                     /protein_id="HDF2579111.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIADTEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMGIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFRDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTTNEGVEIAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYL"
BASE COUNT         1630 a          400 c          777 g         1132 t
ORIGIN      
        1 gagtagaaga atctagacca aacatattag atgctataag aaataaacaa gttgatatag
       61 taataaatac accaactaaa ggaaatgact ctacaagaga tggatttaag ataagaagaa
      121 cagctattga attttctact gaaataatga catctttgga tacactaaaa gctttagtag
      181 aagttaagaa gaaacattta aataaagatg agttaaaagt ttacaatata gctgaataga
      241 aattaagttg attgtatagt ttaagaattt aattattaaa taaaaaaaaa gaggttattt
      301 tttctaggag tttttacttt tgagataact tctttttttt aagaaatttg tagtataata
      361 gaaaaagata aaaaataaat gtaaataagt ataaaactag aatgtaaaag tgaaaaatag
      421 atatagatat ttaaaagctt atatttagtt aatgttcttt agtttgtcta aagagaatta
      481 taggaggtac tgtagtatga aagcaaggtt aatattagaa gatggaacag tttttatagg
      541 aaaggcattt ggatatttag aagaaagtgt aggagaagta gtatttaata cttcgatgat
      601 aggatatggt gaagttttaa cagacccttc ttactatggt caaatagtta ctatgactta
      661 tcctcttgta ggaaattatg gtataaattt atcatcagca gagtctgaaa aagttcaagt
      721 aaagggattc atagtaaggg agaaaagtga ttctccaagt aattttagat gtgaaattga
      781 tatagaccaa tatttaaagc aaaataaagt tatcggactt gaaggaatag atacaagagc
      841 tttgactaag atacttagaa ataatggaac aatgaaaggt ataattacat tagaagacag
      901 taaattagaa gatgttaaac ataaattgga taagttttca aatacagaag cagttagaac
      961 tgttacaaga aaagaagtag agcatataaa aggaaatggt ccaaaagtgg ctgttatgga
     1021 ttttggagta aaaagaaata tattaagatc atttatagct cgtggatgtg atataacaat
     1081 atttccagct acaacatctc cagaagatgt attgagtata aaccctgact taatattctt
     1141 gtcaaatgga cctggagacc cagaagacct agaagatgtt atagaaaata taaaagctct
     1201 tattggtaaa aaacctatag ttggaatatg cttaggacat caacttttag ctttagctct
     1261 tggaggaaaa actgctaaac ttaaatttgg gcatagaggt ggaaatcatc cagttaaaga
     1321 tttagaagaa ggaaaagtat ttataacttc tcaaaatcat ggttattatg tttcagaagt
     1381 tcctgaacaa atgaaagtga cacatataaa tttaaatgat aatactgttg aaggaatgag
     1441 acatgagaag ctagatgtat acagtgttca ataccatcct gaagcttgcc caggaccaaa
     1501 agataatgac tatatttttg ataaattttt agaattagta aaataaataa cattagaata
     1561 gctaactaaa aaacaagaat aacttaaatc aaaaagtttg gtttaattaa catagatgta
     1621 ttaaatagat gtattgatga gtaaatttga acttaagata aaataaagta attaaagttg
     1681 attgtataga tgatgaagat aagaactgtg aaaattgttt agataaggag aaagagttat
     1741 gcctaaatta gatagtataa agaaaacttt agtattaggg tcagggccaa taataatagg
     1801 tcaagctgca gagtttgact attcaggaac acaggcctgc caagcattaa aagaagaggg
     1861 aattgaagtt gtattagtaa atagtaaccc agctactata atgactgata aagaaattgc
     1921 agataaaata tatatagaac cattaacaat agaatttata gaaaaaataa tagaaaaaga
     1981 aagaccagac agtttacttg caggtatggg tggtcagaca ggattaaact tagctgtaga
     2041 attacatgat gctggtatat tagataaata taatgtaaaa gttataggaa catctataga
     2101 atctataaaa aagggcgaag atagagattt atttagagaa gtaatgaaag aaataaatca
     2161 accagtaata gttagtgata tagttacaaa tttagaagca ggtcttgagt ttgccaataa
     2221 gataggatat ccagtagttg taagaccagc atatacgcta ggtggaactg gtggaggtat
     2281 agctgatact gaggaagaat taagagaaat actttcacat ggactacagc taagtcctgt
     2341 tggacaagtt cttcttgaaa agagtataaa aggttggaaa gaaatagaat atgaagtaat
     2401 gagagatgga aatggaaact gtataactgt atgtaatatg gaaaatgtag acccagttgg
     2461 agttcataca ggagacagta tagttgttgc tccaagtcaa actctaagtg atgaagagta
     2521 tcaactactt agaaaggcat caatagacat aataaatgca atagaggttc aaggtggatg
     2581 taacgttcaa atagctttaa acccacatag tttagaatat gcgataatag aaataaaccc
     2641 aagagttagt aggtcatcag ccctagcatc aaaagctaca ggatacccaa tagcaaaagt
     2701 agcagctaag atagctttag gttatacttt ggatgagata gaaaatgcag taactaaaaa
     2761 aacttatgct tgttttgagc caacattaga ttatgtggta gtaaaaatac caaagtggcc
     2821 atttgataaa tttagacatg caaatagaaa attaggaact aagatgatgg caactggtga
     2881 aatcatgagt ataggaagta actttgaggc tgctattctt aaagggataa gatcacttga
     2941 aacaggaaaa tattcattgg ttcatgctcc atcagaaggt agaacattag aagaattaaa
     3001 ggctagagta gtagtacctg atgatgagag actatttgac ttagctgaaa tgataagaag
     3061 aggctataaa gtagaaatga tatcagaaat aactggtgtt gataagtggt ttataaataa
     3121 atttaaatgg atagtagaac aagaagaaaa gttaaaagtt ctaaaaatag aagacttaga
     3181 taaagaatat ttacatgaat taaagaaaaa gggattttct gataaaggta tatctgactt
     3241 aatgaagata agcccagaaa aattatatga attgagaagt ttatataata tacaaccagt
     3301 ttataaaatg gttgatacat gtggaggaga atttgaagct ctatcacctt attactattc
     3361 aacttatgaa caatatgatg aggtagtagt tagtgataag agaaaagttg tagtattggg
     3421 ttctggtcca ataagaatag gtcaaggtat agaatttgac tattgttcag ttcactgtgt
     3481 aaaatcttta agaaaaatgg gaatagaaac tataattgta aacaataacc ctgaaactgt
     3541 aagtacggat tttgatacat ctgataagtt gtattttgaa ccattaacag aagaagaagt
     3601 tttaaatata atagaaaaag aaaaaccaga aggtgtaata ctacagtttg gtggacaaac
     3661 agctataaaa ttggctaagt ttttacatga aaaaaatata cctatactgg gaacagactt
     3721 tagagatata gatgcagcag aagatagaga aaaatttgat gatttactag agagactaga
     3781 tataaataga ccaaaaggaa aaggtgtatg gacaactaat gaaggtgttg aaattgctaa
     3841 ggagttaggt tatccagtat tagttagacc atcttatgta cttggtggtc aaggtatgga
     3901 aataacttat aacgaagaaa aactaattca gtatttgga
//
LOCUS       DAMJWO010000166         3861 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.172, whole genome shotgun sequence.
ACCESSION   DAMJWO010000166 DAMJWO010000000
VERSION     DAMJWO010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3861
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.172"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            118..1608
                     /locus_tag="PC366_003632"
     CDS             118..1608
                     /locus_tag="PC366_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2579112.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
     gene            1866..3362
                     /locus_tag="PC366_003633"
     CDS             1866..3362
                     /locus_tag="PC366_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2579113.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACISACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFEFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            3496..3846
                     /locus_tag="PC366_003634"
     CDS             3496..3846
                     /locus_tag="PC366_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2579114.1"
                     /translation="MKKIVLKDILFLVTTLSIIVILLFVTNITTNSKIKSTSESYLKS
                     DKNSVRQNGIQRSTKNTAFKTTILSTGKSDCILIEIGDKFIMIDTGEDKNGEQIVDKL
                     KEKEINALDYLIKK"
BASE COUNT         1519 a          395 c          763 g         1184 t
ORIGIN      
        1 ctatatatat tcgataaaat aaaatttaaa catataatat tttatgtata tattaataaa
       61 aggacatatt gtgttataat ggtatcgtat aaaatcattt acgggggtgg tattaaaatg
      121 tttcaatttg aaacacaaat acacaaatta agacatgatg ttttaactgc aatagctaga
      181 cttggaaaag aagataacct taccagagaa gcaatggata atattcagta tgaaataata
      241 aaaggtgaga aacctacata cagatgttgt gtttataaag aaagagctat aatatctgag
      301 agagtaaatg taagtatggg gttacaacca ggtcaagata agatagattt agatacaatg
      361 gatatagaag aagatgaaca aattatatat attttggaag ctgcatgtga cagttgtcca
      421 ataaatgaat ttacagtaac agatatttgt agaggatgtc tagcacatag atgtaaagaa
      481 gcttgtaaat ttggagctat aacacatgtc ggaggaatgg cctatataaa tcatgaatta
      541 tgtaaggctt gtggaatgtg taaaaaagct tgtcaatatg atgccatctc agaggttgtt
      601 agaccatgta agagtgtttg tccaactaat gccttaggat ttgatagaga aaatatgaaa
      661 gctatgatac atgaggataa atgtttaaac tgtggagcat gtatgtcagc atgtccattt
      721 ggagcaatat ctgataagag tttgatagct cctgtagcta gaaagttggt tcaaaaagag
      781 aaaatgtatg cggtagtagc tccagctata acaggtcaag ttgaagcaaa tgttacatat
      841 ggtcaaataa aaaatgctat aaaatcacta ggatttgttg atgtattaga agcagcttgt
      901 ggagcagatg cagttacagt tcatgaaagc ttagaatttg ctgaaagaat ggaaaaggga
      961 gaggctttta tgacaaattc ttgttgtcca ggatttgttg gttatataga aaaaacatac
     1021 ccaaatcatg taggaaaaat atcttctaca gtgtctccta tgatagctag tggtagattt
     1081 ataaaaagtc atgaaccaga tgctaaagtt gtattcatag gaccatgtac agccaaaaag
     1141 agtgaggcag ctaagaaaga attaaaagga gctgttgatt atgtacttac ttttgaagaa
     1201 ataatggcat tatttgaggc atttgatata gacttggcta agtgttcaaa tgaagatata
     1261 gatgatgcat caatttttgg aagaggtttt ggagctgctg gtggtcttac aaaagctata
     1321 gaaaattatc ttgctgaaaa aggtattggt gttaattttg aacctgtaaa gatttctggt
     1381 tcaagagaaa tcaagaaaac tatgactatg gctaatttag gaaagctaga aggtaatttt
     1441 atagaaggaa tgatgtgtga aggtggttgt ataaatggtt ctggtaaatt cttatcaggt
     1501 gcaaaggtta aagccacttt tgatagaaaa aattctcaat caactaagaa aagtgtctta
     1561 gcaaatacaa agataaaaga ttttagtaat ataaatttag aaaaataaag ataatacaaa
     1621 gcaacaaaaa tacatattgt taatagagtt gttctaagtt gaggtttaac ttttggacaa
     1681 ctctattttt atttatatat ttaattaatg aacaactaaa ataaaaatta catatataat
     1741 attttgtata taacttaaca aagtatatgc ctatgttata ataatttata gaaataaata
     1801 aaaaatacaa tatacataat agtagaaata tagtaaaaag gtgtgattta tagggaggat
     1861 tacttatgtt tgaatttgaa acgcaactaa aaaggttgaa acatgaagtt ttaacagcag
     1921 tagcaagact atctattgaa gaaaatttaa caaaagaaaa tatagaaaaa attccatatg
     1981 aaataattaa aggagaaaag gcgagatata gatgttgtgt ttataaagag agagaagtag
     2041 ttcttgaaag ggcgcaactt gcattaagtt taactccaaa tagtaaatat ggagatataa
     2101 atccagattc agttagtttg gacacagatg agcaaattat atatatagtt gaagcagcat
     2161 gtgatagatg tccaataaat gaatttacag ttacagagct ttgtagaggg tgtttggctc
     2221 atagatgtaa ggaagcatgt aaatttgggg caatttctta tataaatggg agagcatata
     2281 taaatcatga tttatgtaag gcttgtggaa tgtgcaaaag ttcatgtcaa tatgatgcta
     2341 tatcagaagt tgtaagacct tgtaaaagcg tttgtccaac aggagctttg gattttaata
     2401 gaaacactat gaaagcaatg atacatgaag ataattgtat aaattgtgga gcatgtatat
     2461 cagcatgtcc ttttggagca atatctgata agagtttgat agcacctgtt gcaaaaaaac
     2521 ttgcaaagaa agaaaatatg tatgcaatag tagctccagc tataacaggt caaatagata
     2581 gtaatattac atatggtcag ttaaaaaatg ctataaaatc acttggattt gtagatatga
     2641 tagaagcttc ttgtggagca gatgcagtta cagttcatga aagcaatgag cttattgaaa
     2701 gaataaaatc aggagataat tacatgacaa attcatgttg tccgggattt tttaagtata
     2761 tagagaagat gttcccagat gaaaaagata gaatatcatc tacagtgtct cctatggtag
     2821 caacaggaag attagtaaaa aaaatagatt ctgatgctaa agttgtattt atagggccat
     2881 gtacagctaa aaagagtgag gcaacagaga aaagtttaaa agattcagta gattatgtac
     2941 ttacttttga agaactaatg gcattatttg aagcatttaa tatagattta tcaaaatgtt
     3001 caaatgaaga tataaatgat ggttcgattt ttggaagggg atttggagcg tctggtggac
     3061 ttgccaaatc agtacagaac tatattgctg aaaagggact tagttttgag tttgaaccta
     3121 taaaagtatc tggtccaaga caaattaaaa agacaatgac aatggctaaa ttgggaagat
     3181 tagaaggtaa ttttatagaa ggaatgatgt gtgaagaagg ttgtattaat ggagcaggta
     3241 agtttttatc aggtgtaaaa gctaaaaata cttttgatag aaaaaatgga caatctacta
     3301 aaaagagtgt tttatctaat gataagatta aagaatttga agatgtaaat ttagaaagat
     3361 aattgttttg gtacagtcat ttttttatca tgccacaaat atgcctaaaa ttttcccttt
     3421 ttatatgtgt attttacaga gttaaggttg ctatactata aatatgtaat aaataaaatt
     3481 tataggagct tttggatgaa gaaaatagta ttaaaagata tcctgttttt agttactaca
     3541 ttatctataa tagtaatatt attgtttgta acaaatataa ctactaatag taagataaaa
     3601 tcaacaagtg aatcttattt aaaaagtgac aaaaatagtg tgaggcaaaa tggtatccag
     3661 aggagcacaa aaaatactgc atttaagact actatattaa gtactggaaa gtctgactgt
     3721 atattaatcg agataggtga taaattcata atgattgata caggagaaga taaaaatgga
     3781 gaacaaatag ttgataaatt aaaagaaaaa gaaataaatg cacttgacta tttgattaaa
     3841 aaatagctac gcacactcgt g
//
LOCUS       DAMJWO010000167         3810 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.173, whole genome shotgun sequence.
ACCESSION   DAMJWO010000167 DAMJWO010000000
VERSION     DAMJWO010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3810
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.173"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     misc_binding    399..637
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            701..2620
                     /gene="thrS"
                     /locus_tag="PC366_003635"
     CDS             701..2620
                     /gene="thrS"
                     /locus_tag="PC366_003635"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HDF2579115.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     gene            3388..>3810
                     /locus_tag="PC366_003636"
     CDS             3388..>3810
                     /locus_tag="PC366_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579116.1"
                     /translation="MIEKVEEKSKIIKTSKEYKRTIIEEKDKEWTKKLNDILSRSSFC
                     NDELDKIKALIPKEILTNENVGEVVTEDGYAKPEYDEVFKSLFTLNNEYDLLVNFIND
                     ILKDAPYANRNIKPFTQIKRIIRVETDPTINYIGEKRPR"
BASE COUNT         1481 a          396 c          693 g         1240 t
ORIGIN      
        1 ttattaatag catttagata ttaattgtat ttatttattt gattgtgtta cttattaata
       61 gtatttaagt atttactgta ctacttatta actatattaa gtattgattg tatttaagta
      121 tacaaaacct aaaaagagta caaaaattag aagttagttt taataaaaat tagttttagt
      181 atttatctag tcatatctat catgcatgtg gatacgtttt aaaaatttta aatttatgaa
      241 aatattataa tatcactata aatcaagaga ttaatttaat ataaaaatat aagaatattg
      301 gtttacagct gattgagatg aaaaataatg ggtaattaat atattacatt aatgttgatt
      361 gatgtataac tatctgttat aatgaaaata tattaaaaat catagtgttg aagaggaaga
      421 gtagagtaga aaccattctc agagaatttg ggtctatggc tgagagccca tgtaataggt
      481 ctatttgaaa actaccttgg agctgagctt attagcagta tttgtatttg tactatacgt
      541 gaaagtgctc gggtgacgac cttatagtca tcaagagggt tgtatatact tgtatacgcc
      601 aacttgggtg gaaccgcgaa ttaatatcgt cccaaacata tttggggcga ttttttatta
      661 caaaaaatct aaaaattatt tcaataagga ggaaaaaaca atgattaaag ttgctttaaa
      721 agatggctca ataaaagaat ttgaaaatgc tatttctgtt atggatgtag ctaaatccat
      781 tagtgaagga ttagctagaa atgtggtagc agcgtctgtg aacggagagg ttgtaggtct
      841 ggaccacatt atagatactg attgtgactt gaatttattt aagtttgaag ataaagaagg
      901 taaggaagtt tttagacata catcagcaca tatattagct caagctataa aaagacttta
      961 cccagaagca aagcttgcta taggaccaag tatagaaaat ggattctact atgatataga
     1021 tttagaccat agattagttc cagaggacct agagaaaata gaagctgaaa tgaaaaaaat
     1081 agctaaagaa gatttaaaaa tagaaagatt tgaacttcct agaaatgaag ctttagagct
     1141 tatgaaagaa caaggagaag actataaggt agaacttata tctgatttac ctgaaagtga
     1201 aataatatct ttctacaagc aaggtgattt tactgattta tgtagaggac cacatttacc
     1261 atctactaaa aaggtaaaag ctgttaaatt acaaagtgta gcaggtgcat attggcgtgg
     1321 tgacgaaaat aataagatgc ttcaaagaat atatggaact tcttttgaga aaaacaaaga
     1381 cttagaagag tacttacatt tactagaaga agctaaaaag agagaccaca gaaaattagg
     1441 taaagaatta ggattattta tgatacctga agaaggtcca ggattcccta tgtttttacc
     1501 aaaaggtatg gaacttaaaa atgaattatt aaaattctgg agagaaatac acagaaaagc
     1561 tggatatatt gagatagaat ctccaatcat attaaataga aaattatggg agacttcagg
     1621 acactggtat cattacaaag aaaatatgta tacagttaaa atagatgatg aggattatgc
     1681 tataaaacct atgaactgtc ctggtggatt aatttactat aactctcaac tacattcata
     1741 tagagatttc ccaatgagag ttgcagagct tggtagagtt catagacatg agttatctgg
     1801 tgcattacaa ggattaatga gagttagagc atttactcaa gacgattcac atatattcat
     1861 gttaccagag caaattaagg acgaaataaa aggagtagct aacttaatag atggtatcta
     1921 caaaactttt ggatttgaat ataatttaga attatctaca agaccagaga actctatggg
     1981 aagcgacgaa gagtgggaag cagcagaaaa tggattaaga gaagctttag aagagttagg
     2041 tctaccatat actattaatg agggtgatgg agcattctat ggtcctaaga tagacttcca
     2101 tctaaaagat tgtttaggaa gaacttggca atgtggtact atccaattag atatgcaact
     2161 tccaagacaa tttgataata cttatattgg tcaagatggt gaaaagcata gaccagttat
     2221 gattcatagg gttgcttttg gtagtataga aagatttata ggtatattaa tagagcatta
     2281 tgctggtaaa ttcccagttt ggttatctcc aactcaagtt aagatacttc ctatatctga
     2341 taaatttatg gattatgcaa atgaagttaa gaaagagtta tttgataagg gtataagagt
     2401 tgaattagat gatagagctg aaaaaattgg atttaagata agagaagctc agcttgaaaa
     2461 agtgccatac atgttaatag taggtgaaaa agaagtagct gataataatg tttctgttag
     2521 atcaagagat aaaggtgaaa taggtagtat taaattagat gaatttatag ctagtatttc
     2581 aaaagaaatt gaatcaagag aaagtattat tcaagactaa tatataatat attagtagct
     2641 aagatattgt tatataagat aagtttaatc aatatgttga tatgttgata catagtgatt
     2701 aaatttatga aaagatgagt ataattagag gtacagttaa tcatattttt atgattaatg
     2761 tacctctagt tttttgtatg gtagatttat taataaatat atcatagaag tgttttgaac
     2821 atggaaatat ttatgtgcat tctttaaata aaagtttatt ttttgaatga taattaagtg
     2881 cttgttggta aggttatggc tgtaaaaatc ataactttat ttttatattt gttccatttt
     2941 cataaaaatt attatccctt taagaaaatt tcttaatcct cttgaaatat ttccttttta
     3001 gtctaaagtt aaatttcttt cttcaaaatg aatatttaaa tgaactaaaa tttaagtaca
     3061 ttttctaatc ttatgagtct atttttcata gataattgcc ctataataga agaatctatg
     3121 ttggggctat gtggtgacaa taacagcatt gtcagtgatt aattaatgct ttataaatga
     3181 ttaattagtg ttttatgtta tttttggact taccctctat acatagatta atttatttaa
     3241 ctttagatat agagagaatg tcaagtacat acacagacat tagagtttaa gaaagtgttt
     3301 atggagcaag aacttttaaa agaagtagtg acttagttta atttcaagaa atgataaata
     3361 caaaagagga aaaagagagg tgttgaaatg atagaaaaag tagaagaaaa atctaagatt
     3421 attaaaacat caaaagaata taagcgaact ataattgaag aaaaagataa agaatggacc
     3481 aaaaaattaa atgatatact tagtagaagt agtttttgta atgatgaatt agataaaatc
     3541 aaggcgttaa ttccaaaaga gattttgact aatgaaaatg ttggagaagt tgtgactgaa
     3601 gatggatatg ctaagcccga gtatgatgag gtatttaaat cattgttcac tttaaataat
     3661 gaatatgatt tacttgtaaa ttttataaat gatattctaa aagatgctcc atatgctaac
     3721 aggaatatca aaccgttcac tcaaataaag agaataatta gagttgaaac tgatccaaca
     3781 attaattaca ttggagagaa aagacctaga
//
LOCUS       DAMJWO010000168         3775 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.174, whole genome shotgun sequence.
ACCESSION   DAMJWO010000168 DAMJWO010000000
VERSION     DAMJWO010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3775
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.174"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            306..1682
                     /locus_tag="PC366_003637"
     CDS             306..1682
                     /locus_tag="PC366_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HDF2579117.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSKGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVRKRRFSKLNVHSKVVLFSTATLIFVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPSTIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            1993..2664
                     /locus_tag="PC366_003638"
     CDS             1993..2664
                     /locus_tag="PC366_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HDF2579118.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            2855..3652
                     /locus_tag="PC366_003639"
     CDS             2855..3652
                     /locus_tag="PC366_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HDF2579119.1"
                     /translation="MITNINSKDNEKLKYTRALLKSKNRNKESKFIIEGYRIVMLALE
                     CMANLDYVFINEEFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPK
                     VIRSTMGSIFDMNIIDASQDETVDMLKSLDFNIVSSYLNTENFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKYLI"
BASE COUNT         1448 a          410 c          687 g         1230 t
ORIGIN      
        1 ttcaaaaaag tatatgaaat ttatactggt aaaatgataa ataaatttta agtacaaaat
       61 agtaaaagct atgatagttt tagacccatt atatgtaaaa aatatagatg tttttggtgc
      121 aatttaaatt aaaagatata tataaaaatt taaaatattc caaacagaaa ttataaaaat
      181 tactatcatt gtctttatgc aatatttata ctataataga ataataattt agaggaaagc
      241 tctaaaaata aacaaattaa gggtcttaac agtagtgatt ttatgttaag gaggtataaa
      301 gaaagttgaa aacaatagtt agaagactta ttctctacgc agatggaatg cgtcctactc
      361 aaataatggt atctgggttt gctgcgatta ttgtaatcgg agcattgttg ttaacactcc
      421 cgatagcgtc gcagagtgga gagagtatag gcttattaaa tgctctattt acggctactt
      481 cagcggtttg tgttactggt ctagttatgg tagatacagc aacttattgg agtttatttg
      541 gacagatagt tataataaca ttgatacaaa ttggtggtct tggatttatg accgtagcca
      601 caatgttttc acttatggca cgaaaaaaaa tacaactaag agaaagatta ttaatacaag
      661 agtcattaaa tcaagctgat ttatcgggac ttgtaagact tacaagattt gtattaataa
      721 taaccataac aatagaggga ataggtgcac tggttttatc aactgtcttt attccacaat
      781 ttggtttgtc taaagggata tggtatagtg tatttcacgc aatatcagcg ttttgtaatg
      841 ccggatttga cttgatgggc agtgtaagtg gcccatttac atcgttaaat tcttatgtaa
      901 acaactttac agtatcaatg actgtttgcg cacttatagt gcttggaggg ctaggattcc
      961 ctgttgtact tgatattgta agaaaaagaa gattttcaaa attaaatgtg cattctaagg
     1021 ttgtattgtt ttcaactgct acacttattt ttgtgggtgc attatttatt tttcttatag
     1081 aatttaatca aaaagctact atggcggact tgcctttaaa gggaaaagta ctatcagcaa
     1141 tatttcaatc agtaacagca agaactgctg gttttaatac acttgattta gctactttac
     1201 gagaaagtag tgtatttgta atgataattt tgatgtttat tggagcatca cctgcatcaa
     1261 ctggtggggg tataaaaaca acaacactag ctgttttaat cattacagtt agaagttttc
     1321 tatcaggaaa atcagatata gaagcttttg aaagaagatt agctccatca actataaaaa
     1381 aatctcttgg tatatttgta atcagtatat cagcagttat ttttggaaca ttgattattt
     1441 caataactca gcctaatttt acattagttc aatcagcttt tgaggttaca tcagcacttg
     1501 ctacagttgg ttcaagttta gctggaactc caaatttaaa tgctttaggt aagattataa
     1561 taataatctt tatgtttatg ggtagagttg gttctcttac tttatttatg gctatacttt
     1621 ctggtggtag aagaaagagt caaccaatca gatatgcaga aggtaaaatt atggttggtt
     1681 aagttaccaa ggagtaatat aaatttataa tggatttaga gtagcactgt aaatctgttg
     1741 ataaaataaa tgagcctaga tgtaattata tgaagaaata aaatcaacta ataaacaaaa
     1801 ttaattaatg aaataaaaaa acagggaaat aaaatacaaa taaaaaggta aatcaaaatt
     1861 aaattaatct gtgtatataa aattatatat tgtgtataag ttttgtatgt gtaaagtata
     1921 taagttttgt atgtgtaaac aattaattta agagatatta tataaattgt gtattaggga
     1981 ggaagtttcg agatgaagca atatatagtc attgggtgtg ggagatttgg aagttcagtt
     2041 gcgtctacta tgcatctttt aggacatcaa gtaatggcaa tagacaaaaa tgaagattca
     2101 gttcaaagta tatctgacaa ggtaacccat tcacttatag tggatgttac tgatgagcaa
     2161 gcgttaaggt cattaggttt aggtaacttt gatgtagcag tagttgcaat aggttctgat
     2221 ataagggcat ctataatggc gactcttata gccaaagaaa tgggtgtaga gttgataata
     2281 tgtaaggcaa aggatgaatt acaagctaaa gtgctttata aaattggcgc agatagagtt
     2341 gtatttccag aaagagatat gggagtaaga gttgcacaca atttagtttc ggataatata
     2401 ttagaccata ttgaacttga cccagagtat tcaattgttg aaatcgtaac tccaaatagt
     2461 tgggttggca agacacttat agagcttgaa ttaagagcta gatatgagat aactgtactt
     2521 gctataaaaa caggtaaaaa tataaatgtt acaccttctc cagatgagga acttacagcc
     2581 ggaagtatcc tagttataat cggtcaaaat actagtataa cagcgataac atctggaaat
     2641 aaggggataa ttagaagaag ataatttact atttaatata tatttaattg caatgaaagt
     2701 aaagagtatc atataattat gaatagttat atgatactat ttttatttaa tcgaaggtag
     2761 tatttatttg taagattaga taaagagaag ttaaattaaa agtaaggagg ctgtgctaat
     2821 ataaaaattt ataagttatt agcatttaga taaaatgatt acaaatataa acagtaagga
     2881 taatgaaaag ttaaagtata caagagcact attaaaatca aagaatagga ataaagagtc
     2941 aaagttcata atagaaggat acagaatagt aatgcttgca cttgaatgta tggcaaacct
     3001 tgattatgta tttatcaatg aagaatttga aaataagaaa gaacatgtaa aactattaga
     3061 agatttggat aaaaaaaaca caaagatata caagactact aataaaaact ttaaagaatt
     3121 agtggataca gaaaatactc aaggaataat aggtgtagtt tcatttaaga aaaaaaaatt
     3181 aagtgaaagt ataaataaaa aagataaatt tgtattgatt ttagatagaa tacaagaccc
     3241 aggaaatatg gggactataa taaggactgc tgattctgct ggagtagatg ccataatagc
     3301 actaaaggga tgtgtcgata tatacaaccc aaaagtaatt aggtctacta tgggttctat
     3361 ttttgatatg aatataattg atgcttcaca agatgaaact gtggacatgc ttaaatcatt
     3421 ggattttaat atagtttcaa gttacttaaa tacagaaaat ttttatgaca aaatagatta
     3481 tggttcaaaa gtagcattgg tgataggaaa cgaagcaaat ggaataaatg aagaacttgt
     3541 atcaaagtct gatattttgg ttaagatacc tatatatggt aaagccgagt cgttaaatgc
     3601 tgcgataagc tctgctatac tgatgtatga aataaaaaaa tacttaattt aatgtattgt
     3661 aataaatata atgtcatgtt ataatcttga attaaatagt agagtatcaa aaatagtcaa
     3721 tatatattaa aaaaataatt aaattaatta tatattagat gtatatcata taaaa
//
LOCUS       DAMJWO010000169         3466 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.175, whole genome shotgun sequence.
ACCESSION   DAMJWO010000169 DAMJWO010000000
VERSION     DAMJWO010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3466
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.175"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            112..1710
                     /locus_tag="PC366_003640"
     CDS             112..1710
                     /locus_tag="PC366_003640"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HDF2579120.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDMDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILAVTDIIKEGSYLIYKAEDSLIANAFDVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
     gene            complement(1945..2136)
                     /locus_tag="PC366_003641"
     CDS             complement(1945..2136)
                     /locus_tag="PC366_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium protein"
                     /protein_id="HDF2579121.1"
                     /translation="MAGLTTEPGGGGVLSGYFAGFLFGGTTFTINNFSSTTVGIRNGQ
                     SAGTAATLTIFRIADTVMT"
     gene            complement(2305..2898)
                     /locus_tag="PC366_003642"
     CDS             complement(2305..2898)
                     /locus_tag="PC366_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HDF2579122.1"
                     /translation="MRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYY
                     NLRTITWNDRVSMENIRGYLPIGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNY
                     PYQIFEFTSSRDCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSIGPMG
                     ATGPTGATGNSSQPIANFLVNAPSPQTLNNGNAITGW"
     gene            complement(2899..3045)
                     /locus_tag="PC366_003643"
     CDS             complement(2899..3045)
                     /locus_tag="PC366_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium protein"
                     /protein_id="HDF2579123.1"
                     /translation="MRKIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFF"
BASE COUNT         1263 a          477 c          464 g         1262 t
ORIGIN      
        1 tataatattt tttcactaaa tttttttctt tttacaacaa atactcacta ccttttgata
       61 taatattttt atcaattatt attatattca agttttgaaa ggagtattaa aatgagttta
      121 ttagttttcg gacataaaaa tccagataca gattcaatat gttctgcaat ttcattagca
      181 catttaaaga acaaactagg aataaaagca acagcttatg ctttaggaga tatcagaaaa
      241 gaagctaaat atgccttgga ttactttaag gtagatgcac ctgaaatttt agataatgtt
      301 agaatacaag ttagagattt aaattatgat aaagtagtac ctttaacacc aacttcatct
      361 atattagagg cttataacct tatggatgaa aaaaatgtta aaacactacc tgtaacttat
      421 gatgatggaa cttttgctgg tatcattact atgaaagaaa tagctaaaaa tctacttcat
      481 caacacttta caactataca cacatcacta tcaaacattt gtaaaaacct taatggtact
      541 attcttgtgg actgtggtga agatataaaa ggtagagtag tcactttatc atttggaatg
      601 gagactctaa tagagacttt aaaagaagga gacatagcta ttgttggaga tagatatgat
      661 agtattgaat atgctattga tacaaaagtt aaacttttaa tacttactaa tcatacagag
      721 atttcaaaag atttgctagc tcttgctaag ataaatggag tgtctgttgt ttctgttgaa
      781 agtgacaatt ataaaacttc taatgtaata aatcaatgta gtttcttaga ctctatagaa
      841 gctacagaaa atttaattac attcaaagaa gatgattata tggatgaaat aaaagagatt
      901 atgctagaaa caaacttcag atcttatcca atattagatg atgataataa gtttttaggt
      961 ttagtttcaa aaggtcatct attaaaccca tctaaaaaga atgttgtttt agttgaccat
     1021 aacgaatatg ctcaaagtgc tgatggaatt gaacaagcaa acatagttga aataattgac
     1081 catcataaac ttggtggtat ttctactgat gttcctatgt catttagagt tatgcctgtt
     1141 ggatgcaata gtactataat ttatcaaatg tacaaagaaa acaatgttga gataccttat
     1201 gaaatagctg ggcttctttt atctgctata ttatcagata cattattatt taagtctcca
     1261 acaacaactg atatggataa gaaagcttgt gaagaattaa gtaaaatagc aaaagtagac
     1321 atggaaaaat acgctatgga tatgtttaaa tgcggtactt ctttagatga atatactata
     1381 gaagaaatag taaatatgga ttttaaagaa tttaatatga gtggacatag agttggtatt
     1441 ggacaagtat ttaccttaga catagactct atatttgcta aaaaagatga gtttttatct
     1501 tatataaatt cgactgatta tgacaaacta attcttgcgg ttacagatat aatcaaagaa
     1561 ggttcttatt taatctataa agcagaagat agcttaattg ctaacgcatt tgatgttgaa
     1621 ggtgttcaag gtacatttgc accaggtgtt gtatcaagaa aaaaacaatt agtccctaat
     1681 ttaactactg caatcaaaaa ttttaaataa tataaaattt ttaaataacg aaaactgtct
     1741 caaatctata tttgagacag ttttttatta tacatatatt gataataaag ttaaataaaa
     1801 atccataaat ttaaaatttt tatgaatata ttttattatt attgttattt tattcattct
     1861 aaaataggta aaactcaata tataaaaata cttttgtcat ttaaataaaa cctaaatagt
     1921 ttttaagatt attttagaca cgttttaagt cataacagta tcagctattc taaatatcgt
     1981 caaagtagcc gcagttcctg ctgattgccc atttcgtatc cctactgttg tagatgaaaa
     2041 attatttatt gtaaaagtag tccccccaaa taaaaaacca gcaaaatatc cagaaagtac
     2101 tcctccgcct cctggctcag tagtaagccc tgccaaatct tttcctccta aaattgggaa
     2161 taggatagca aaagaatatt gatttatact tgatgaacct ggttgtaatg ctactgaaac
     2221 tgatatataa tacacaccat tttcttgtac tgtaaacgta ccatttgcat ctactgttat
     2281 acttgaacta tttcctatta ttgtttacca acctgttata gcatttccat tatttagtgt
     2341 ttgtggagat ggtgcattta cgaggaagtt agcaattggc tgagaggaat tgcctgttgc
     2401 tcctgttgga cctgttgctc ccattggtcc tatacttcct gtcgctcctc ttggtcccat
     2461 tggacctgta attctaattg gaagacactc acatttagga taacaattat ctataattct
     2521 atcttcaaat gttacaagta tatacggttt gttacaatcc ctactagatg taaattcaaa
     2581 aatctgataa gggtaattta aagataaagc taacccataa ttaggatatt tattcattgc
     2641 ccatgctttt atagttcccg taatatttaa acaaatatag ttggatgtat cacttatccc
     2701 aattggtaaa tatcccctga tattttccat agacactcta tcattccatg ttatagttcg
     2761 taaattataa tattcactta ttcttttaat ttcaatatct actttttctt taaaaatatg
     2821 attcttattt gaatcaatat gaataaataa ctctgctttt aatatacttt tgtcttttaa
     2881 tatatctggt attctcactt aaaaaaaagt aatcaacttt tcttttacaa aactatttga
     2941 acatttactt cctattaagc aataatctaa attactaaag tttttatctg gatatttttt
     3001 agatataaaa gtatcatcat ttaaataaag tataattttt ctcatttata atccctccat
     3061 tttgggtcta tatcatacta tgtttaaaat acatgcttag ttacaataca attaaaattt
     3121 atagtattaa atttttatat aataatgctg atttctacaa aaaaagaaca tgtcattaga
     3181 aacttctaat agcatgttct ttttcattat tatatattac actttaaatt attccttgac
     3241 tggcttagct ggtgtaaact aaaccagtct ttctaaaata ttaagcactt ttttcttatt
     3301 atgtttttta ggatttattg tctctattat tgtaaaccaa agttataaaa ttgtaaatag
     3361 aatatattac cataacaata tttttttata agtaaaaatt ataaaaaacc ttatttttat
     3421 taaatagaat aaataaaata agtttaaaaa atactgaaat aagtgt
//
LOCUS       DAMJWO010000170         3247 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.176, whole genome shotgun sequence.
ACCESSION   DAMJWO010000170 DAMJWO010000000
VERSION     DAMJWO010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3247
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.176"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            49..660
                     /locus_tag="PC366_003644"
     CDS             49..660
                     /locus_tag="PC366_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HDF2579124.1"
                     /translation="MINDIKNKFKNYKPYINGYKNMKRASVLIPIIEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            958..1296
                     /locus_tag="PC366_003645"
     CDS             958..1296
                     /locus_tag="PC366_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HDF2579125.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSKKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVPFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
     gene            complement(1703..3139)
                     /gene="miaB"
                     /locus_tag="PC366_003646"
     CDS             complement(1703..3139)
                     /gene="miaB"
                     /locus_tag="PC366_003646"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HDF2579126.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPDMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESINSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERVRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPG
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHDRFNRVLEAVNRISAEINDGYKDRIVEVLVEGRSKNNENKFAGRTRQNKLVNFEGG
                     NDDLIGKLVMVKITEPRTFSLNGILVNN"
BASE COUNT         1122 a          477 c          368 g         1280 t
ORIGIN      
        1 taaaactcaa ttatataatt tttaataata ttattttagg aggtaaaaat gataaacgat
       61 attaaaaata aattcaaaaa ttacaaacca tatataaatg gatacaagaa tatgaagaga
      121 gcatctgttt taattccaat aatagaaata aataacacac actatatatt atttgaagtt
      181 cgctcaaaaa atttgaagca tcaacctagc gaaatttctt ttccaggtgg taaaatagaa
      241 tcaggtgaga ctccatatga agctgttatt agagaaactt gtgaggaact tggaactttt
      301 agtgacaata tagaagtaat atcaagtctt gacctcctta taacaccagt aaagtttatc
      361 atacatccat acttaggata tataaaaaat attaataatt taaatataaa caaggatgaa
      421 gttgaccata cttttttggt tcctataaaa tatcttttag agaatcctcc aaatacttat
      481 agtaatactg taaaagtttt tccagatgaa aatctaccat atggttcaat tccaaaccaa
      541 aaagattata aatttgaaag tggaagttat cctattctgt tttataaata taaagattat
      601 gtaatttggg gaatgacagc aaaaatacta gaaaactttt taaatttttt atcagaataa
      661 cactcataat aaatcatcaa aacttttaca taagaaattt ataaaagttt ctaaatttaa
      721 caattctaaa atatcaataa ctatattttg tagcactttt ttattttatt attgtttgaa
      781 tatttgatgg ttttcaatgc aatttcaaca taaatactat gtattagtgt atactgttga
      841 tgaattaaag tatgataatc tatttaataa agtatgaagt aaatgatttt aatgtgtctt
      901 tatggtaaaa ttactaataa gtaataaaat taattaaaat atatggaggt gcttataatg
      961 tttgctgtag gatttgttgt tataattgca cttgcctttt tcattttaag tgtactatta
     1021 tttaatggaa aagccagtat gctactagca ggttataact ctatgagtaa gaaagaaaaa
     1081 gcacgatacg ataaaaaaaa attatgtaga agttctagca ttgttacttt tattgtctct
     1141 ataatgctat ttattatggc atttttggga tatagaatag agagtggtca aatggacgaa
     1201 aaaaaaatgg ttcccttttc tataatattt ataatagtca tactttccag tgtatttttt
     1261 aatatcctct actctaacaa aaaatgtaaa aaataaatag ttgtaagttg agcagttaat
     1321 tataaaagat tgactgcttt ttcatgtata ttgactactc ttattaaata ttttaacatt
     1381 taaaaatcta tgtaaaaata atgaatatag tacaaacttc taataatgat tttacctttg
     1441 tggttacagt ccactatata taatttaata tgataacatg gaattactaa tgacaactaa
     1501 gtaagctttt ataaaatata ataaaacaaa aatagatgta caatgaaatt atatcttata
     1561 tcaaatttat ttttattaat agcaaaaact tacattagca taacatatga caaattcgct
     1621 taaaataaaa atttttaata taatttgttc tatagtacat ctatttcgat tagtttacat
     1681 aattttatta ttttgtacaa tattaattat ttactaatat cccatttaat gaaaaagttc
     1741 taggttcagt aattttgacc ataactaatt taccaattaa atcatcattt ccaccttcga
     1801 aatttacgag tttattttgt ctagttctac cagcaaactt attttcatta tttttacttc
     1861 ttccttcaac tagaacttca actattctat ctttatatcc atcatttatt tctgcagaaa
     1921 tcctatttac agcttctaac accctattaa atctatcatg ctttatatct tctggtattt
     1981 gattttccat tttagcagca ggagttccct gtcttttaga ataaataaat gtaaaagctg
     2041 aatcatatct aactttttca accacatcta aagtgtccaa taaatcttct tctgtttctc
     2101 ctgggaaacc aatcattaag tctgtagaaa aagcaatacc tggaacttcc tttttagctt
     2161 tttctattat ttctaaataa tattcctttg tataatgtct attcattttt ttcaaaaggc
     2221 tactgcttcc acattgtatt ggtagatgta aaaactcaca caccttatca caatctctaa
     2281 ttgcgtatat tacttcatca gatatatctt ttggatgaga tgtcataaat cgaacccttt
     2341 caattccttc tatatcattc acttttctta aaagttctga gaatgaaact ggattttcaa
     2401 gtgtcttacc ataagaatct acattttgtc caagtaaagt gatttctttc gttccatttg
     2461 caacaagctc ttttatctcg ttaattatat cttcaggagt tctacttctt tctcttcctc
     2521 ttgtgtatgg gactatacaa tatgtgcaga aattattgca tccatacatt atatttacaa
     2581 atgcttttaa ttcaaatttt ctattacttc taagaccttc tattacttct ccatccacat
     2641 cccatacatc cactaacatt ttgtcagaat ttattgattc tgtaagtaat tgcggaaatt
     2701 tatatagatt atgtgttcca aatataaggt ctacatgttt atattttttt cttaattcct
     2761 ctacaacatg tggttgttgc atcatacatc cacatacagc tattttcata tctggatttt
     2821 ttccttttag atgttttaat tgtcctaagt taccatacac ttttagctct gcattttctc
     2881 taactgcaca ggtgttatat attattaaat cactttcttc aaccatcatt gacatttggt
     2941 atcccatctc ttctaacatc gaacataatt tttctgaatc atgttcattc atttgacacc
     3001 caaaggtttg agtaaacacg agttttctct ttccagttct gttgaagtat tcttcatttt
     3061 gtctgtgtat ttgttctata tatttatctt gttcttgtat tttctctata ggtattgtta
     3121 cttgttttct tttgctcacg tctattcctc ctagttaatt tcttatatta cacataacct
     3181 taattatatc aaataagaaa aatcttttaa agatattatt atttttctag ttgtgtttta
     3241 atagtaa
//
LOCUS       DAMJWO010000171         3208 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.177, whole genome shotgun sequence.
ACCESSION   DAMJWO010000171 DAMJWO010000000
VERSION     DAMJWO010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3208
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.177"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(145..666)
                     /locus_tag="PC366_003647"
     CDS             complement(145..666)
                     /locus_tag="PC366_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDF2579127.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKAVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENIIIKTEVPETAKAVLEQQLVLAQAL
                     ETWINSLKDNMGN"
     gene            794..2158
                     /locus_tag="PC366_003648"
     CDS             794..2158
                     /locus_tag="PC366_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDF2579128.1"
                     /translation="MKESNKKIELLGSAPISKALLSMGLPTMIGMMITALYNLVDAYF
                     VGGLGTSQMGAISVAFPLGQLVVGLGLLFGNGAASYIARLLGHGDNEKAGKVVSTSIY
                     SSIIVGTLVIIVIMIFLNPILKLLGATKSIMPYAISYASIYVVSSIFNIFNVTMTNIV
                     TSEGAAKTTMCAMLLGALLNMILDPIFIYTFGLGVRGASIATAISQIASTLVYVGYIL
                     SKKSIFSFRINECCFSKEIFSEILKIGIPTLIFQLLTSLAITLTNMEATKYGDSVIAG
                     MGAVTRITSLGSLVVFGFIKGFQPIAGYNFGSKNYDKLHIAIKTSILWTTIFCVVLGL
                     ILVLFPKSIISQFTSGDILLIENGSKALRANGFSFMLFGFYTVYSTLFLALGKAKEGG
                     FLGMCRQGVCFIPIILIIPVFYGLNGILYAQPIADLMAAIIAGFMSIRLHKELNLLKI
                     NGMH"
     gene            2347..3024
                     /locus_tag="PC366_003649"
     CDS             2347..3024
                     /locus_tag="PC366_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDF2579129.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSDYKKGNPVH
                     CGDSDCIGILIIKSGTIRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQINSSVFAKLSTENIHAELFSYKLATERFSDVMWAMQQILFMSFDKRLAS
                     FLIDEIAKNGSSTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
BASE COUNT         1008 a          447 c          504 g         1249 t
ORIGIN      
        1 aaaagtttaa cattctccct caattaagtg agctttattt taaatatact tttcagttta
       61 tatcatttgt ttcatttttt ctaatatctc attattaaat atgctggttt ttgtttaatg
      121 attattaagt tagcttctct aattctaatt ccccatatta tcttttaaag aatttatcca
      181 ggtttccaat gcttgtgcta gcaccaactg ttgctccaac actgcttttg ctgtctctgg
      241 tacttctgtc tttataatta tattttcctc aatagttttc tttaactctt gaacattctc
      301 ttcaatatta ttgagacata atttctgttt ttctggtgta aggctattta aatttactat
      361 aacagcatta aaatctaaaa gaatatttat tggtttgcta gatgtatcaa acattaaatc
      421 taaaaaatgt gtctcaccta attcagttaa tgaataaact gctttttctg gcatttttcc
      481 attcttcaca gttttacttt caatatatcc cttttgttct aattgaatta cttttttata
      541 aattgatggt gtacttattt taacccaacg tgatatattc ctgtattcca ctgccttttg
      601 aatatcataa gcactcttgg gttgttgctt tactattccc aatacaatta aatctattgt
      661 agccataaaa atcatctcct ttagttttct tactattgac aaatactata aattatagta
      721 ctattttcca tacttactat aatttatagt attataattt agacttaatg tcaatagaag
      781 aggagtgtta agtatgaaag aaagtaacaa aaaaattgaa ttattagggt ctgccccaat
      841 ctcaaaagca ttgttatcta tgggattacc taccatgata ggtatgatga taactgcatt
      901 atacaatttg gttgatgcat actttgtggg tggacttgga acaagtcaaa tgggagctat
      961 atccgttgca tttccattag gtcagcttgt tgtgggatta ggattattgt ttggaaatgg
     1021 agctgcttca tatattgcca gacttttagg ccatggtgat aatgaaaaag caggaaaagt
     1081 ggtaagtaca tctatttaca gtagtattat agtgggtaca ttagttatta ttgtgattat
     1141 gatttttctc aatccaattt taaaattgtt aggagctaca aaaagtatta tgccttatgc
     1201 aatatcttat gctagcattt atgtcgtgtc atctattttt aatatattca atgtcactat
     1261 gactaatatt gtcacaagtg aaggagctgc taaaacaact atgtgtgcta tgttattagg
     1321 tgctttgctt aatatgattt tagacccgat attcatttat acttttggtc tgggggtaag
     1381 gggtgcttct attgcaacag ctatctcaca gattgcttca acacttgttt atgtaggata
     1441 tattttaagc aagaaaagta tatttagttt tagaattaac gaatgctgtt tttcaaaaga
     1501 aattttttca gaaatcctaa aaattggcat acctacatta atatttcaat tattgactag
     1561 tcttgccatt acattaacta atatggaggc tacaaagtat ggtgattctg tgatagctgg
     1621 aatgggtgct gtaacacgaa taacatcttt aggtagtctt gttgtatttg gttttataaa
     1681 aggtttccaa ccaattgctg gttataattt tggttcgaag aactacgata aattacatat
     1741 agcaataaaa acttccatat tatggactac aatattttgt gtagtgcttg gtcttatatt
     1801 ggtgcttttc ccaaaatcta taatttcaca atttacaagt ggtgacattc tattaataga
     1861 aaatggtagt aaagctctta gggcaaatgg gttttcattt atgctatttg gattctatac
     1921 agtgtattct acattattcc tagcactagg aaaagcaaag gaaggtggat ttttaggtat
     1981 gtgtagacaa ggcgtctgtt ttatccctat aattttgatt attcctgtat tctatgggtt
     2041 aaatggtatc ttatatgcac aaccaatagc tgatttgatg gctgctataa ttgctggttt
     2101 tatgtctata aggttacata aggaacttaa tcttttaaaa ataaacggta tgcattagtt
     2161 atacaaacct actatcatca aaacatatta ctttctcatt aatagcaaga atatatatta
     2221 tcatattttt tctacataaa tcatactatt actatctgac taaataatcc tcttaacaaa
     2281 ctacttgtca atttatctat tcacttgtat catgggatta taacaattta agaaaggaga
     2341 tattgtatga tttcacaaaa tgaaattgat atacttacac atagcttgcc tttttgggat
     2401 aaacttactg acttacaaaa agaattatta atttcttcag caaatacctc ggattacaaa
     2461 aaagggaatc cagtacattg tggtgatagt gactgtattg gtattttgat tataaagtct
     2521 ggaacaatac gtacatacat actttcagat gaaggtcgag aggttacact gttccgactt
     2581 gatgatggag atgtatgtat tttatcagct tcctgtattc taaaaacaat aacttttgat
     2641 gtctatgtag atgctgaaac ggactgcgat attatacaga ttaattcctc tgtttttgca
     2701 aaattatcta cagaaaatat tcatgcagag ttattttcat ataaattagc taccgaacgt
     2761 ttttctgatg ttatgtgggc tatgcaacaa attcttttta tgagttttga taagcgtttg
     2821 gcatcttttt taattgatga gatagctaaa aatggcagta gcactataaa tatgactcat
     2881 gagcaaattg ctaagtatat gggtagtgcc agagaagttg tatcgagaat gttgaaatat
     2941 tttgctagag aaggtattgt gtctttatct cgtggtggta taaaagtatt ggataaggat
     3001 aaacttcgtt ctttgacact gtaaaagtgt gtctcaaaat gaacttttta gttcatgagg
     3061 cactcttttt tgtgtgaaat caaatatatt ttcataattt caataataaa aaagatactt
     3121 atatctattt ttatatagta tcttatttga tatttacatt tattttttat gtatattttt
     3181 atattttaat aatttagttt aactattt
//
LOCUS       DAMJWO010000172         3002 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.178, whole genome shotgun sequence.
ACCESSION   DAMJWO010000172 DAMJWO010000000
VERSION     DAMJWO010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3002
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.178"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            80..2437
                     /locus_tag="PC366_003650"
     CDS             80..2437
                     /locus_tag="PC366_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HDF2579130.1"
                     /translation="MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQ
                     IFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGE
                     SDIIIKNKDDFLYSGSFVVSGEAFVRVENIGKDNYANKIVNDAKISKKHNSQLRNSLN
                     SILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAV
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMG
                     NICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEF
                     IFKEKNKKIRIEVEKYSKKGNRVIVLAHSDSYMEDNNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDNDIYEAVDK
                     YSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPF
                     VPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNI
                     VEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGG
                     LFSFVALSRELILITMALAILMPIMIKVMLFVLDEILETIVPDLN"
     gene            complement(2523..2840)
                     /locus_tag="PC366_003651"
     CDS             complement(2523..2840)
                     /locus_tag="PC366_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HDF2579131.1"
                     /translation="MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
BASE COUNT         1153 a          331 c          478 g         1040 t
ORIGIN      
        1 taaaatataa aaattgagaa ttttataata tatttgtaga tttgagtata aaaaagtgct
       61 aagttgaaag gagtaaaata tggataaggt taatttagaa aggtatagtt gtgatataaa
      121 tgttggttta aataaaaatc aacttcaaag tagaatagat gataatttaa ttaatgcatt
      181 tgataatgga aaaaccaaaa catataaaca aatttttaaa gacaatatat ttacactttt
      241 taatctcata aatattgttt tagtctgttt attagtttca gttggttctt ttaaaaatac
      301 cttatttata tttattgctg taattaatac tattatagga gtaatacaag agataagagc
      361 taaaagatta ttggacaatc tatctgttat agtttcaaat aaggtatctg tcataagaga
      421 aaaagagaaa aaagagattg atgtacaaga attagtatta gatgatatta tgattttaaa
      481 aacaggtaat caaatttgtg cagattcaaa agttttaaat ggaaaattag aggtaaatga
      541 gtctttggtt acaggtgaat ctgatattat tataaaaaat aaagacgatt ttttatattc
      601 tggaagtttt gtagtttctg gagaagcttt tgtaagagtt gaaaatatag gaaaagataa
      661 ctatgcaaat aagatagtta atgatgcaaa gatttctaaa aaacataatt ctcaacttag
      721 aaattcatta aattcaatat taaaaattgt aggtataata ataattcctt taggaattat
      781 attgtttgca aaacagcatt ttggaaatgg agattctata gctacatctg tagtaggtac
      841 agtggcagct gtaaatggta tgataccaga gggattaaca ttacttacga gcattgctct
      901 agctgtagga actataaaac ttgctagtca taaaacttta gtgcaagaac tgtactgtgt
      961 agagactctt gctagagttg atacactatg tcttgataag acaggtacaa ttacagaagg
     1021 taaaatgcaa gttgatgata tagtaatgtt ggaagaagtg gatattaatg aaataatggg
     1081 gaatatatgt aattctctca aagatgataa tgcaacacta aatgcaataa gagataagta
     1141 taatgtttta gatacgtata aagctaagaa tttaatacca ttttcttcag aaagaaaata
     1201 cagtggggtt acctttgaaa ataaaggtac atatttatta ggtgcatttg agtttatatt
     1261 taaggaaaaa aataaaaaaa ttagaataga agttgaaaaa tattctaaaa aaggaaacag
     1321 agtaatagtt ttagctcata gtgattctta tatggaagat aataatattc ctgaagatat
     1381 aaagccacta gcttttatat tgatattaga taaaattaga gatgaagcta aggaaacttt
     1441 agaatttttt tacaatgaag gtgtagatat aaaaattata tctggtgaca atcctataac
     1501 agtaagtgag gtagctagaa aagcaggtct taaaacggct agtaatttta ttgatgcaac
     1561 aacacttaaa aatgataacg atatatacga agcagttgat aaatacagtg tttttggaag
     1621 ggtaagccca caacagaaaa aacaaatgat tttagcatta aaaaaacaaa atcatacagt
     1681 agctatgact ggagatggtg taaatgatgt gctagcgctt aaagaagcag attgcagcat
     1741 tgccatggca tctggaagtg atgttactaa gaatgtttct aatttagtct tattagattc
     1801 aaactttgca tcaatgccaa aggttgttat ggaaggacga aaggtaatta ataacattca
     1861 aagagcatct tctttgtttt tagtaaagac aattttttca ttcttcttgt cactattaac
     1921 attattcttc ttcagtagac agtatccatt tgttcctata caattatcac taattggagc
     1981 tgtaacagtg ggtataccat cattcttctt agctcttgaa gcaaacaaaa gtagaatttc
     2041 aggaaacttt ttactcaata tattaaaaaa tgctttacca ggagcactat gtgtgacagt
     2101 aaatgtaatt attgtttaca atatagttga atatttaggc tatagttcaa gtgtattttc
     2161 tacaatgtgt gctatattaa ctggtgtatg tggtctttta atattaagac aacaatgttt
     2221 gccatttaat aaagaaagat tatttttaat tgtaagtatg actattgcat ttgttattgg
     2281 gattctattt ttaggtggat tattctcatt tgtagcattg agtagagaat taattctcat
     2341 aactatggca ttagcaatat taatgccaat tatgataaaa gttatgttat ttgtcttgga
     2401 tgagatatta gagacaattg ttccagattt aaattaattt taaaatgata taaataagag
     2461 cagttttagt tgaactgctc tttttagatg tgtttaattt tatataagaa tatgtatttt
     2521 tattaatcag ctatatatga gcaacagtag tcaacaactt cattaacctt taaatcaaaa
     2581 cttgaatcac taggaacatt aaatttttgc ccttctttat aagttacaaa ctcattgctt
     2641 ccaggcagtt ttacatccat acttccagca agcatctcca ttatttcttc ttctctagta
     2701 gaaaaagtat attctcctgg caacattaat cctaaagttt ttctttctcc attaggcagt
     2761 attattactc tgctacttac cttaccatca aaataaacgt ttgccttctt tactgcagta
     2821 acattcttaa attcactcat tagataaaac ctccaaaatt atttgtacat atatattata
     2881 taaaaataat gtaaaaaatg ctatatattt gcaaaaaaaa atttagtatt tattaaaaaa
     2941 attaataaga ataaaaaaga gatgaaattg cttaaattga taaaaaatat aaaataaatt
     3001 gc
//
LOCUS       DAMJWO010000173         2926 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.179, whole genome shotgun sequence.
ACCESSION   DAMJWO010000173 DAMJWO010000000
VERSION     DAMJWO010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2926
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.179"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..387)
                     /locus_tag="PC366_003652"
     CDS             complement(<1..387)
                     /locus_tag="PC366_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2579132.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLR
                     IMGKSNIPLFSFKHLFNGEISPIVLAL"
     gene            complement(1196..2233)
                     /locus_tag="PC366_003653"
     CDS             complement(1196..2233)
                     /locus_tag="PC366_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2579133.1"
                     /translation="MIKSKKILSLIIAGVLGVSMLTGCSQNDGSNASNENKKTDSKKQ
                     KNIGISQLVEHPSLDKAKKGFIKALEDKGYKDGDNIKIDFQNAQNDMPTTQSIASKFV
                     SDKKDLIYAISTPSAQAAYNATKDIPIIMTAVTDPVEAGLVKSLEKPGGNVSGTSDYL
                     SIDKTLELVKTLTPKAKKIGVIYNTSEVNSKIQVDSLHDYAKKNNYEVVEKGISTSSE
                     VNQAISSLVGKIDVLYVPTDNLIVSSMPIVSKVANENKIPIIASEEGSVSSGALACCG
                     IDYEKLGYKAGELAIEVLEGKSVGDIPVTTLDETEIIINEDTLKALDMQKLSADNIKY
                     IKSDENAKSAK"
     gene            complement(2330..>2926)
                     /locus_tag="PC366_003654"
     CDS             complement(2330..>2926)
                     /locus_tag="PC366_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003399531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDF2579134.1"
                     /translation="GLIKESSGQITLDSTTITNLAEYKRTQIVSRVFQDPSLGTCPSM
                     TVRENLSLALNKGKLLNLKKCLRHKTNNLEHLLEGISLDLKKYLDIKVQYLSGGQRQS
                     LSLIMSSLASPKVLLLDEHTAALDPKTSNEVIELTDKIVREKNITTLMVTHNLKHALQ
                     YGDRLIMLHKGEVVLDVKDKEKENLTVEEILEKFEYAV"
BASE COUNT          992 a          445 c          381 g         1108 t
ORIGIN      
        1 taaggctaaa actataggag atatttcccc attgaataag tgtttaaagc taaatagagg
       61 aatatttgat tttcccatta ttcttaaatt gatagagtat agcattccca taactaaaat
      121 accagaaagt aagttagata tcttaaactt aatgtgaaga atccctgtaa caagaccagc
      181 agtacaacca cataagatag ccattaaagt tgctactaca ggagaaatac cattagtaag
      241 agaaaatgct acaatagaag cacccattgt atagctacca tcagcagaca tgtctggaaa
      301 atctaggatt ttgtaagtta tataaacccc cagtgccata atcgataaaa ttaaactttg
      361 cgtcattaca gatataatac ctgacataaa taaaacactc ctttgaaaat atttttataa
      421 ttttaattat ttgctaattt tgtgtataaa aaaaccacat agtgtacaaa actatgtggt
      481 aaaaacacga ataagccaca tagtttaatc tatgtggctc ttatatagtt aaatgaaaac
      541 tttataaaca atatagccaa catagataca atcccaaaat tttaatagtc ttaaggggtc
      601 tgtatctatg ttaaaacgta ggtacaaacc ctaaaaatag tggctataat aataataata
      661 ttttctattg tttaataaag tattcataat tatctctccc ttttaatatt ttaattagtc
      721 agaaaattat atgtattctc gacttgttat aaattataaa ttatacaata ataaaagtca
      781 actgctaaat ttaattaaaa tactaaataa tgtatactca gaatactttt aaattaatgt
      841 attgtttgca aaaaacgtta tcctaagtta taagtgaatg tggaaatttt atcaaaatat
      901 ttactaaata tggaataact agacatgtat atcaatcaaa tatcataaaa aaaagctgtc
      961 tggagaatat taaaattctt ttggacagct caagtagtga ttagaaagtt atataacttt
     1021 cataatcagt cgtcaatata gacgactttt atggaaaatg aataacttta tatgcaatat
     1081 tcaaattgct acaataagca caattttcaa agggttaggg tggataagag tacttattat
     1141 ataaagtttt catattacct acttcatatt acctattttt tgaaattaat aagttttatt
     1201 ttgcagattt tgcattttca tctgacttta tatactttat attatctgct gataactttt
     1261 gcatgtcaag tgcttttagt gtatcttcgt taattattat ttcagtttca tctaatgtag
     1321 taactggtat atcgccaaca gattttcctt ctaatacttc aatagcaagt tctccagcct
     1381 tataacctag tttttcataa tctattccac aacaagctaa agcaccagaa gatacagaac
     1441 cttcttcaga ggctattata ggaatcttgt tttcattagc aactttagaa actattggca
     1501 tagaagaaac tattaaattg tcagtaggga catataaaac atctattttg ccaactaaac
     1561 tagaaatagc ttggttaact tcacttgaag tgctgattcc tttttcaact acttcataat
     1621 tatttttctt agcataatca tgtagagaat caacctggat ttttgaatta acttcactag
     1681 tattgtatat aacccctatt ttctttgctt ttggagtcaa tgttttaacc aattctaatg
     1741 ttttatcaat tgaaagataa tcagatgtac cagaaacatt tccacctggt ttttcaagag
     1801 atttaacaag tccagcttct acagggtctg taacagcagt cattattatt ggaatatctt
     1861 tagtagcatt ataagctgct tgtgcagatg gagtagatat agcatatatc aaatcttttt
     1921 tgtcggatac aaacttacta gcaatacttt gtgtagtagg catatcattt tgtgcatttt
     1981 ggaaatctat ttttatatta tctccatctt tatagccttt atcttcgagt gctttgatga
     2041 atcctttctt tgctttatcc agagacggat gttccactaa ttgactaata cctatatttt
     2101 tttgtttttt gctatctgtt tttttatttt catttgaagc attggagcca tcattttgag
     2161 aacatccagt aagcattgat acaccaagta ctcctgctat aattaaactt aatatttttt
     2221 tactttttat cattttattt tcctccctta aaatttaata attatatttg ttcatatatt
     2281 catatgatag attataaata tttctgatta aaactaagat tttaatttct tatactgcat
     2341 attcaaattt ttctaagatt tcttcaactg ttaaattttc tttttcttta tcttttacat
     2401 ctaatacaac ttcaccctta tgaagcatta tcaacctatc tccatattga agagcgtgtt
     2461 tcaagttgtg agtaaccata agtgtagtta tatttttttc tcttacgatt ttatctgtta
     2521 actctattac ttcatttgat gtttttgggt caagtgctgc tgtatgttcg tctagtaata
     2581 agaccttagg acttgctaag ctagacataa ttagtgatag tgattgtctt tgacctcctg
     2641 aaagatattg tactttaata tctaaatatt tttttaagtc caaagaaatt ccttcaagta
     2701 agtgttccaa attattcgtt ttatgacgaa gacatttttt taagttcaat aatttccctt
     2761 tattaagtgc tagagataaa ttttctctaa ccgtcataga aggacaagtt ccaaggcttg
     2821 ggtcttgaaa aactctactt actatttgag ttcttttata ctcagctaaa tttgttatag
     2881 tagtactatc taaagtaatt tgaccagaag attcttttat aagccc
//
LOCUS       DAMJWO010000174         2814 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.180, whole genome shotgun sequence.
ACCESSION   DAMJWO010000174 DAMJWO010000000
VERSION     DAMJWO010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2814
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.180"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            174..1097
                     /locus_tag="PC366_003655"
     CDS             174..1097
                     /locus_tag="PC366_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HDF2579135.1"
                     /translation="MGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESINLTKTKIY
                     SNLRDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSKKAG
                     ALIYSIHPIFAFSNKNTNIKKMKDICFSIEGDNEQDDLVIQNFIDGLGNQFFIRDKDT
                     SSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNGFTK
                     ALTGPVSRGDITPIRKHLSVLNKKDEDIYKILSLNLLKIIALGNDNSLKGTKNITIEN
                     AIENLISKSEKYKEIYKLLGGKNDEKYHTDF"
     gene            1072..1899
                     /gene="panB"
                     /locus_tag="PC366_003656"
     CDS             1072..1899
                     /gene="panB"
                     /locus_tag="PC366_003656"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HDF2579136.1"
                     /translation="MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGAKNALIVSDMPFLSYHVSIEDAVKNAGR
                     LIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIADMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGVFGDFVPKFVKQYANIGDIMKDSIKNYILEVNTGAFPQEKHSFSINESELEKLY"
     gene            1918..2766
                     /locus_tag="PC366_003657"
     CDS             1918..2766
                     /locus_tag="PC366_003657"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HDF2579137.1"
                     /translation="MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAV
                     KENDKVVVSVFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNINTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLN
                     PKNIKELITAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNF
                     TFELNI"
BASE COUNT         1121 a          340 c          460 g          893 t
ORIGIN      
        1 ttgtcaattt tttatgaaaa tggtaagata tttatggatg gtatcttgtt ataagaacta
       61 tactttaaat gtttttaatt attttgtctt atgtaactca tatcctcagg aatgagatta
      121 gaaattaaga tgttgtatca caaagtggag gtgatactat taaaataggc tttattggtt
      181 ctggaaaagt tggaacatct ttggcaaatt attttttatc aaaaggttat tgtgtttcag
      241 gcttttatgg aaggaatcaa ttatctttat tagaatcaat aaatttaaca aaaacaaaga
      301 tttacagcaa tttgagagat ataatttatg aaaacgatat attatttatt acaacatcag
      361 atgattctat tgaaattata gacaaaaaac tttccaaatt taatttaaaa cataaataca
      421 tttgccacac aagtggctct ttaaaatcta gtatattgtt ctgttcaaaa aaagcaggtg
      481 cattaattta ttctatccat cctatatttg cattttccaa taaaaatacc aacataaaaa
      541 aaatgaaaga catttgtttt tccatagaag gtgataatga acaagatgat ttagttattc
      601 aaaatttcat agatggtttg ggaaaccaat tttttataag agataaggat acttcatcca
      661 cttatcatct agctaatgtt ttagtttcaa atttagtatt atctttacta gatataggag
      721 taagttactt tattaaatta ggtttatctg aagaggaatc tttaaaagct atcagtcctt
      781 tagtaaaaaa aaatatagaa aatatacttg ataatggctt tactaaagct cttactggtc
      841 ctgtttctcg tggagatata acaccaataa ggaaacatct atctgtattg aataaaaaag
      901 atgaggatat ctacaaaata ctatccttaa acctactaaa aataattgcc ttaggaaatg
      961 acaattcatt aaaaggtaca aaaaatatta ctatagaaaa tgcaatcgaa aatttaataa
     1021 gtaaatctga aaaatacaaa gaaatttaca aacttttagg aggaaaaaac gatgaaaaat
     1081 accatacaga cttttaagaa cgctaaatat gaaggaaaaa aactatctat gcttactgct
     1141 tatgactact caattgcaaa aataatggat gaatgtgata taaatggtat tttaataggc
     1201 gattcattag gaatggtcat aaaaggtgaa gaaaacactc tatctgttac tatagacgaa
     1261 attatatatc atacaaaagc tgtaaaaaat ggtgcaaaaa atgccttaat cgtaagtgat
     1321 atgccttttc tatcttacca tgtttctata gaagatgcag ttaaaaacgc tggtagactt
     1381 ataaaagaag gaggagctca tgctgtaaag ttagaaggtg gctcaaacgt tataaagcaa
     1441 atagaaagca ttgtaaatgc tcagatacct gtaatggggc atttaggatt aactcctcaa
     1501 tcagtaaatt catttggtgg gtttaaggtt caaggaaata ccagtgaaac agcaagacaa
     1561 cttattgaag atgctaaatt aatagaaaaa gcaggtgcat tctctattgt ccttgaagga
     1621 gttcctacga aaatagctga tatggtaact aattctattt caattcctac aataggtata
     1681 ggggcaggaa ttaactgcga tggacaaatt ttagtttatc aagatatgtt gggagtgttt
     1741 ggagattttg ttcctaagtt tgtaaagcag tatgcaaata taggagatat aatgaaagat
     1801 tcaattaaaa attacatcct agaagttaat acaggtgcat ttccacaaga aaaacacagc
     1861 ttttcaataa atgaatctga gttagaaaaa ttatactaat attaaggatg gtacaaaatg
     1921 cttgtaaaag aaattaaatt actaagaaat ataatcaaag attggagaaa acatggctat
     1981 tctatagggc ttgttacaac aatgggattt ttacatgaag gacaccaaag tcttataaaa
     2041 aaagctgtaa aagaaaatga taaagtagta gtgagtgtat ttgtaaatcc aactcaattt
     2101 ggaccaaatg aagattttaa tagctatcca agagatatag ataaagattt taaatattgt
     2161 atggatagtg gagcaacagt agtctttaac ccatcaccag aagaaatgta tttaaaaggt
     2221 aattgtacta ccattaatgt ttctggactt acagattttc tttgtggagc taaaagacct
     2281 gttcattttg gaggtgtctg cctagttgtt tcaaagtttc taaatatagt aacacctgat
     2341 aaagcttatt ttggagagaa ggatgcccaa caattggctg taattaaaag aatggtcaag
     2401 gatttaaaca taaatacaga aataataggc tgtcctataa ttcgtgaaaa tgatggatta
     2461 gcaaaaagtt cgagaaatac atatctctct gaggaagaac gaaaatctgc tctaatatta
     2521 aataagagct taagtttagc aaaagaagaa ttagtaaaag gcaatctaaa tccaaagaat
     2581 ataaaagaat taataacagc taaaataaat tctgaacact tagcaaaaat agactatgtt
     2641 gaaattgtag atagtgagac attacaacct gttaagcaaa tagaacattc tatccttgtg
     2701 gcaattgctg tgtttatagg aaaaaccaga ctaattgata attttacatt tgagttaaat
     2761 atatagtata taattttata taatatatct aaaaaataat agaataccta aaaa
//
LOCUS       DAMJWO010000175         2803 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.181, whole genome shotgun sequence.
ACCESSION   DAMJWO010000175 DAMJWO010000000
VERSION     DAMJWO010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2803
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.181"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            389..2200
                     /locus_tag="PC366_003658"
     CDS             389..2200
                     /locus_tag="PC366_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HDF2579138.1"
                     /translation="MKKKYDFLIYSAIWLVIIIFFIFSLYHSIEHIKIISHTGTIRSE
                     TQKVVKQELNNERNDDLIKRLDNILIKLRTGNGENGFQRCDNKEFQQKLNQMDSMWES
                     MKKEIIKVRNGASGDKLYKLSEEYSVLSNQIVFISEKHSNAKLYSFATALFIYLIFST
                     ISLLIWEYYNKKRFKRIFYTDNLTKIKNQVAFENRAIEILYNASNKEYVLLNIDIDNF
                     KYINDTHGYEYGDKVLIIVAAALSKTFNIKETCARIGSDNFVILAKYRDSLLEDIREM
                     LTNAIISELDMNVTQTISYCIGAYLVEIDNLGYKSINSIMDKANIAHKVSKTRGISST
                     VWYNENLLKQLQMENSIYNYMYKAIENEEFHMYLQPKFQISSLNVVSAEALVRWFSPE
                     LGFLSPDEFIPLFEKSGFIIELDFYMLKKACSFVKKTFMKKNQYTYPIAVNFSRVTIY
                     QNSFYQRFLDTVKEYEIPFKYIEIEVTESAFNEISQPVISILEELKKLGFLISMDDFG
                     SGYSSLSLLCSLSINGLKLDKSLLKETFNREKVYSIIQCIIEMSHRIGMSVVCEGIET
                     KKDLEFLNTVKCDVGQGFYFSKPIEEKEFFNKYVTKK"
     gene            complement(2288..>2803)
                     /locus_tag="PC366_003659"
     CDS             complement(2288..>2803)
                     /locus_tag="PC366_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579139.1"
                     /translation="QSIYKFIEKIPFVKKDNSNFNYTNYYMEFEDIPEYYEVNFNNYL
                     YIITRFSFIPDGTEIFFTWEEIHYWDEKVATEKTFINGETLVDSYNFPNNEVKDYIQK
                     RESLYIETKKYYEEKGLKIERHALGSEDGEYVELTNDSILYLLDIEAVEIREQSKNIE
                     EFLYKYKKRFK"
BASE COUNT         1058 a          284 c          409 g         1052 t
ORIGIN      
        1 ataaattcaa agagttaaat tgtaggtaaa tagtatttta attatttatt aaaatataga
       61 ttatgtatat gccaaattta aaaagagaca taaagacatt atacaaatat attattgggg
      121 tgatatttta taagaaaaga agtgatgcag taaattaatt gagcaattta aaaatgattt
      181 aatgatagtg ttgatgaatg tttaaaaaga aattttagaa aaacgtatat tgctgtttgt
      241 gttggaggtg atgaatttgt ataatttata gggtataaat gattaaacta cttaagataa
      301 atacatatca ctgtaaaata ttgataatca ttttttataa gagattgatt atttgcaaat
      361 tatatatatt acaaatgagg taacaataat gaagaaaaaa tatgattttt taatttattc
      421 tgctatttgg ctagttatta ttattttttt tatattttct ctatatcata gtatagagca
      481 tattaaaatt ataagtcaca ctggtactat tcgcagtgaa actcaaaagg ttgttaagca
      541 agaattgaat aatgaaagaa atgatgactt gataaaacga ctggataata ttctgataaa
      601 gctaagaaca ggtaatggag aaaatggatt tcaaagatgt gataataaag aatttcaaca
      661 aaaactaaat caaatggatt ctatgtggga atctatgaag aaagaaatta taaaagttag
      721 aaatggtgct tcaggtgata aattatataa attgagtgaa gagtattctg tgttgtctaa
      781 tcaaattgtt tttatatctg aaaaacactc taatgcaaaa ttgtattctt ttgctactgc
      841 actatttatt tatcttatat tctcaacaat aagtctttta atttgggaat attataataa
      901 aaaaaggttt aaaagaatat tttatactga taatttaaca aaaataaaaa atcaggttgc
      961 atttgaaaac agagcgattg aaattttgta caatgcatct aacaaagagt atgtactgct
     1021 aaatattgat attgacaatt ttaaatatat taatgataca catggatatg aatatggaga
     1081 taaagttcta ataatagttg cagctgcact ttctaaaact tttaatatca aagaaacttg
     1141 tgcaagaatt ggttcagata attttgtaat acttgcaaaa tatagagatt ctcttttaga
     1201 ggatattcgg gaaatgctaa ctaatgctat aatctctgaa ttagatatga atgtaactca
     1261 aactatatct tattgtatag gagcgtactt agttgaaatt gataatttag gttataaatc
     1321 catcaattct ataatggata aggcaaatat tgcacacaag gtaagtaaaa caagaggaat
     1381 ttcctccaca gtatggtata atgaaaatct gttaaaacag ttacaaatgg aaaatagtat
     1441 ttataattat atgtataaag cgatagaaaa tgaagaattt catatgtatt tgcaacctaa
     1501 atttcaaata tcttctttaa atgttgtaag cgcagaagct cttgtaagat ggttttctcc
     1561 agaacttggt tttttatcac cagatgaatt tattccattg tttgaaaaaa gtggatttat
     1621 tattgaattg gacttttata tgttaaaaaa agcgtgttca tttgtaaaaa aaacgtttat
     1681 gaaaaaaaat caatatacat atccgattgc agttaatttt tcaagggtta ctatttacca
     1741 aaatagcttt tatcaaaggt ttttagatac tgttaaagaa tatgaaattc cttttaagta
     1801 tatagagata gaggtaactg aaagtgcttt taatgaaata tctcaaccag ttatttcgat
     1861 tttagaggag cttaaaaagt taggattttt aatttcgatg gatgattttg gatcaggata
     1921 ctcttcatta agtcttttat gttctctatc tattaatgga ttgaagttag ataaaagctt
     1981 acttaaagaa acatttaacc gggagaaagt atatagtatt attcagtgta ttattgaaat
     2041 gtcacatcgt ataggcatgt ctgttgtatg tgaaggtatt gaaactaaaa aagacttgga
     2101 atttttaaat acagttaaat gtgatgtagg acaagggttt tatttctcta aaccgataga
     2161 agaaaaagaa ttttttaaca aatatgtaac taaaaaataa tataattatt tttatcagtc
     2221 tatacattga gtcattttat atttcgttaa atgactcaat gtattgttat gtattttaaa
     2281 atataaatta tttaaaacgt tttttgtact tatatagaaa ttcttctata ttttttgatt
     2341 gttctcttat ttcaactgct tctatatcta gtaaataaag tatagaatca tttgtaagtt
     2401 caacatattc accatcttct gaaccgagtg catgtctctc aatttttaat cctttttctt
     2461 cataatattt ttttgtttct atatataatg attctcgctt ttgtatgtag tctttcactt
     2521 cattatttgg aaagttatat gaatccacta atgtttcgcc atttataaaa gttttctcgg
     2581 tagcaacttt ttcatcccaa taatggattt cttcccaagt aaaaaatatc tcagttccat
     2641 ctggaatgaa tgaaaacctg gtaataatat ataaataatt attgaaattt acttcataat
     2701 attcaggaat atcttcaaat tccatatagt aatttgtata attaaaatta ctattatctt
     2761 tttttacaaa gggtattttt tcaataaatt tatatattga ttg
//
LOCUS       DAMJWO010000176         2650 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.182, whole genome shotgun sequence.
ACCESSION   DAMJWO010000176 DAMJWO010000000
VERSION     DAMJWO010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2650
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.182"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(114..584)
                     /locus_tag="PC366_003660"
     CDS             complement(114..584)
                     /locus_tag="PC366_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HDF2579140.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYKELFEQEIELDLGKNVTFKGGFAI
                     QEDFAWLTGINPDTIIQKSNNMELYFEVDDFDEFIEKLNYYKDVEFVHKPLKHEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLSEGYSVEETSKIIQHPIEFVKQCENSKE"
     gene            complement(1329..1718)
                     /locus_tag="PC366_003661"
     CDS             complement(1329..1718)
                     /locus_tag="PC366_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HDF2579141.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYQWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEKDV"
BASE COUNT          821 a          471 c          167 g         1191 t
ORIGIN      
        1 tattttcttt attttaattt aatttatgac atttgtcaaa tactagtcct atatattatc
       61 ttgaattagt tccactacaa ttaatttcta ctaaataatt ataatttaaa caatcattcc
      121 ttactatttt cacactgctt tacaaattca attggatgtt gaattatttt agaagtttct
      181 tctacagagt atccctcaga taaatatctt ctagctataa cttccataga ctctcctatc
      241 tcaataatat gcttatctgg gtcataaata cgcactactc tttgttgcca ttcatgtttt
      301 agtggcttat ggacaaactc tacatcttta taataattga gtttttcaat aaattcgtca
      361 aaatcatcaa cctcaaaata aagttccata ttatttgatt tttgtataat tgtatctgga
      421 ttaatccctg taagccatgc gaagtcttct tgtatagcaa atcctccttt aaatgttaca
      481 tttttgccta agtccaattc aatttcttgc tcaaataatt ctttgtaaaa tttttttgat
      541 acttcaatat ccttcactgc taataatgaa acctgatatt tcataaattt tcctcctaat
      601 tttttatttc tattttttca gtatcttcta ttaacatttt tttctctatc tcttcagtac
      661 cttttattag tcctttattt ttactttttt agtatcttct attaacactt ttgtttctac
      721 ctcttcagta tattatatca atcttttatt tttatttttc aatatcttct attaacactt
      781 ttatctctat ctcttcagta ccttttatta atcttttgtt tttatttttt caatatcttc
      841 tattaacact tttgtttcta cctcttcagt atcttctatt aatcctttat ttttactttt
      901 tcaatatctt ctattaacac ttttatctct atctctttaa tatcttctat taattcttta
      961 tttttatttt ttaaatatct tcattaattc ctatttattt tatcatctta aatacgaaaa
     1021 cactgtgtca tatttgcaaa atatatattg tcatctatat taaagcttca caatttatat
     1081 ttaaaaattc tctttaatca cactacctct atttaaaaag ctaccttaat tatacttata
     1141 agtaaaggta gctttttaaa tttaattaaa tagaatatcc actatcaatt tatatttaat
     1201 ttatttagat tcacattata gtatcataat ccacttataa tcatttgtca tattacttaa
     1261 gtagactaat atattacata aatacactta catacacttt atattaatgc tataagaaat
     1321 acgtttgctt atacgtcttt ctcctcttct tttagatttt ttatccactc ttcaataagt
     1381 aagatatcat ctttgctcaa attaatattt tcatgtaatg acaacaataa actttttata
     1441 gaagaatcat gaatatttct aaaaaaatct cttgtctcaa ctcctatgta ttccttttct
     1501 ttaattaaaa cttcataatg tgtatattta tctatctttt gagaatttag aaatcttttt
     1561 actactaatc tagataaaag agtcaaagtt gtcgtttgtt tccattgata tttttgctcc
     1621 attcctaaaa caatatctct agatgttact ttggaatctg atttccatat aaatttcatt
     1681 atctttaatt ctgattgtgg caactttttt atagtcatga taaaaccttg ctactcagaa
     1741 tatagacaag caatatccat aataaaattt ttcgattaaa tacatcttat acggatttat
     1801 ataagctcag acttataaga tatttttcaa tcttaatcct aaatttagct atttgtacac
     1861 ggtaaatata tataaataat gtcaaaattc tcttgtatta tattgcttaa ttttatgaga
     1921 tattttgtac tcagctatct attttggata cttgtccagt agctctcctt tcttttaaac
     1981 tctttgattt taaatatttg tatttcagta aatcctactt cctaaatttt ttatttacta
     2041 caacttatta ctgaacttcc tacttcctaa acttttcatt tactacaact tattactgaa
     2101 cttctcactt actaaatttc ttacttacta taaattataa ctaaacttct cacttactaa
     2161 atttcttact tactataaat tactactaaa cttcctactt tctaaatttc ttacttgcta
     2221 taaattatta ctaaacttcc tactttctaa atttcttact tactataaat tattactaaa
     2281 tttcctactt tctaaatttc ttacttacta caaattatta ctaaacttcc tactccctaa
     2341 atttcttact tgctacaaat tattactact aaacttccta ctccctaaat ttcttacttg
     2401 ctacaaatta ttactaaact tcctacttcc taaatttctt acttgctaca aattattact
     2461 aaacttccca ctttctaaat ttctcgctta ctaccactta tcactaaact tcctactttc
     2521 taaatttctt gcttactacc acttatcact aaacttttta cttcttaaat ttcttacttc
     2581 ttaagaataa tgttaatttt aattttaaga ttatagtttt tgccttgttt aattgaaaca
     2641 ttctatataa
//
LOCUS       DAMJWO010000177         2554 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.183, whole genome shotgun sequence.
ACCESSION   DAMJWO010000177 DAMJWO010000000
VERSION     DAMJWO010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2554
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.183"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            78..377
                     /locus_tag="PC366_003662"
     CDS             78..377
                     /locus_tag="PC366_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579142.1"
                     /translation="MKWIKWYSITCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKKNPVDGTTTIYYSYDNSTHIVRLSHPEDYSRKINWDKVSNIRFD"
     gene            701..2356
                     /gene="ilvD"
                     /locus_tag="PC366_003663"
     CDS             701..2356
                     /gene="ilvD"
                     /locus_tag="PC366_003663"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020457899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HDF2579143.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSAM
                     EGVGACKDGTVSEEELEELAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRIAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIEFNLDFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGKTIGENIRNCEIENEEVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFGKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIENRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
BASE COUNT          989 a          275 c          483 g          807 t
ORIGIN      
        1 aaattttatc gtatgtataa atattataaa tatatggaaa taataatagt atattttggt
       61 aaagtaggag gaattttatg aaatggatta aatggtatag tattacatgc atatgtattt
      121 ttatagtagt agctttttat atgtttatat ttcctaataa aatagaaact attgatactt
      181 catctgcata tagctttgtt gaaaagaaag taccaaatag tgctgtatat caaggataca
      241 aaaagaatcc agttgatggt actactacaa tttattacag ctatgataat tcaactcata
      301 tagttagatt atcacatcca gaagactatt caaggaagat taattgggat aaagtttcaa
      361 acatcagatt tgattaatct ttaatattta taaaagtcta tatatctaag gcaaatatat
      421 tattaatctt attcatagtt gagcactttc tattatagaa gtgcttcttc tgatttatat
      481 cataaaatat tactcaacaa tttgtaaaat atattagttt ataaaatata ttgaaaagat
      541 aatattatat aatacgattg tgtaagatat tgataaaaaa tcgtaataaa ttttcattag
      601 tatatgctaa tattttttta caattttcgt aattaattaa tagaaaaata tattataata
      661 atattatgaa aatttaaaaa agtaagaaag aggtaatatt atgagaagtg atataaaaaa
      721 aggaatagaa ggagctccaa agagagcgtt aatgtatgga atgggtctta ctaaagaaga
      781 aattgaaaga ccattaatag gtatagtaaa tgcacaaaat gaggtgattc ctggtcatct
      841 gcatcttgat gaaatagcag aagctgcaaa aaatggagta agaatgagtg gtggtttgcc
      901 attagaattt cctgctatag gggtatgtga tggtatagct atggggcatg tcggaatgaa
      961 ttattccctg gcttcaagag aattaatagc agattcaata gaagctatgg ctatggcaca
     1021 tggttttgat gctttggtac ttatacctaa ttgtgacaag atagtgccag gtatgttaat
     1081 ggctgctgca agacttaata taccaagtat tgttgtgagt ggagggccta tgcttccagg
     1141 taaaaaaaat ggaaaagtat atgattttaa ctctgcaatg gagggtgttg gagcatgtaa
     1201 agatggaaca gtaagtgaag aagaattaga agagttagcc atgaactctt gtcctggatg
     1261 tggttcatgc tctggacttt tcacagcaaa tagcatgaat tgtttaacag aagctttagg
     1321 catgggtata ccatataatg gtactgctgc gtcacattct ggagaaagaa aaagaatagc
     1381 aaaatatgca ggtatgtatg ttatggagtt acttaagaac gacataaaac ctagagatat
     1441 tttaacaata gatgctttta aaaatgctat agctgttgat atggcaatgg ctggttctac
     1501 aaatacagta cttcacttac ctgcaatagc ttatgaatca ggaatagagt ttaacttaga
     1561 tttttttgat gaaataagtg aaaaaactcc ttgtttaaca aaattaagtc caagtggaaa
     1621 acatcatatt gaagatttac atatggcagg aggaatacca gctataatga acgaactttc
     1681 aaagataaat ggaataaatt tagattgcaa aaccgtaaca ggcaagacta taggggaaaa
     1741 tataagaaat tgtgaaatag aaaatgaaga agtaatacat acattaaaga atccatatag
     1801 taaccaaggt gggcttgcaa tattgaaagg aaatcttgct ctaaatggag ctgttgtaaa
     1861 aaagtcagca gttgcagaag aaatgttagt tcatgaagga ccagcaagag tttttaattc
     1921 agaagaagaa gctgtaaatg ctatttttgg taaaaaaata aacaaaggtg atgttatagt
     1981 tataagatat gaaggtccaa agggtggtcc aggaatgaaa gaaatgctat ctcctacatc
     2041 agcagttgca ggaatgggac ttgataagca tgtagcactt cttactgatg gtcgtttttc
     2101 aggagcaact agaggagcat ctataggcca tatttctcca gaagctatgg aaggtggttt
     2161 aatcggacta gttgaagaag gagatataat ttctataaac ataccagaca aaaaattaga
     2221 gttaaaagta gatgaagttg aaatagaaaa tagaaaatta aaatttaaac ctttagaacc
     2281 gaaaataaag catggatact taagtagata tgctaaattg gtaacatcag caaatacagg
     2341 agcagtttta aaatagtgaa ctatatttac gaaaattaga aaaaattaag aaaatattaa
     2401 ttggatatct taggtgttat agcactaatg aggtatcctt tttattttgt atgaaaaata
     2461 tactgtttgt atacaaaaat attaaagata ttttagtaag ttttgtatat aagcaaacat
     2521 gtatttttta atatagttat ctaaatatta tttt
//
LOCUS       DAMJWO010000178         2445 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.184, whole genome shotgun sequence.
ACCESSION   DAMJWO010000178 DAMJWO010000000
VERSION     DAMJWO010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2445
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.184"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            43..777
                     /locus_tag="PC366_003664"
     CDS             43..777
                     /locus_tag="PC366_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDF2579144.1"
                     /translation="MKQNKYDDDRFFNKYSKMERSTNGLAGAGEWHVLKKMLPDFKGK
                     RVLDLGCGFGWHCQYAVENGAISAVGVDISEKMLKEARNKTQLDNINYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGNFVFSVEHPIFTAYGSQEWYCDK
                     DGNNLHWPVDRYFEEGVRKSNFLGEEVIKYHKTLTTYLNTLMKTGFEILEIIEPQPEE
                     KLLDTIPDMKDELRRPMMLLVSAKKR"
     gene            complement(919..1410)
                     /locus_tag="PC366_003665"
     CDS             complement(919..1410)
                     /locus_tag="PC366_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HDF2579145.1"
                     /translation="MNNQQQEVYKKLDELSIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
     gene            1759..2142
                     /locus_tag="PC366_003666"
     CDS             1759..2142
                     /locus_tag="PC366_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579146.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKVVLKSPEYIGSHPKKPGKSVEFIKKIDNYILVATELDTKKGYLYV
                     SSMYAIKEAKLESRVNNGRVKQYDG"
BASE COUNT          953 a          276 c          359 g          857 t
ORIGIN      
        1 agagtgttgc taagtgaata tatttaaaat ggaggaaact ttatgaaaca aaataaatat
       61 gatgatgata gattttttaa taaatacagt aaaatggaac gttctacaaa tggattagca
      121 ggtgctggag aatggcatgt tttaaaaaaa atgttacctg atttcaaagg aaaaagagtt
      181 ttagatttag gatgtggatt tggatggcat tgtcaatatg cagttgagaa tggagcaatt
      241 tctgctgttg gagttgatat ttcagaaaaa atgttaaaag aagctagaaa caaaacgcaa
      301 cttgataata taaattacat atgtatgcct attgaagata ttaattttcc aaaagatagt
      361 tttgatgtag ttattagttc cttggcattt cattatattc aatcatttga agatatatgt
      421 aagaatataa gtaattgtct ttcaaataaa ggtaattttg tattttctgt tgaacatcct
      481 atatttactg catatggaag tcaagagtgg tactgtgata aagatggcaa taatctacac
      541 tggccagtag atagatattt tgaagaagga gtacgtaagt caaattttct aggagaagag
      601 gttataaaat atcataaaac attaacaact tatttaaata cgttaatgaa aacaggattt
      661 gaaatattag aaattattga acctcaacca gaagaaaaac tgttagatac aattcctgat
      721 atgaaagatg agctacgtag acctatgatg ttacttgtat ctgcaaaaaa aagataagta
      781 aatataaata atcattattg tagaaaaaaa ttgtagaaaa taattacact aatggagatg
      841 attataccag tggtattaat tacaccagta gtaaggaggc aaaagcattc gttgcttttg
      901 ccatttttta agttgcaatt atacttctac gtagtatatt tcgtttccat tttcttctat
      961 aagctttttc atatcttcaa attttaaaaa tacagtagca gtattatcat ttggatgtat
     1021 acctatttta tccattttta ataaatcctt atcaaataca acttttacaa cagcctcttt
     1081 atcatttaat ataccaaaag gagtcacagc tcctttagta agtttcaagt atttttgaag
     1141 tctttcttct gatgcaaaac taagaggttt actatcaatt tgttgacgaa tatcttttaa
     1201 atctgctttt ttgtctttac ctaatacaac taaaaaatgt tcttttcctt tagcatcacg
     1261 aagaaatagg ttttttacaa caaattccat atgtaatgtt tttaattctt ccatttcttc
     1321 aattgtataa actggtggat gatttacagc ctcataaggt atgcttaact catctaattt
     1381 tttatatact tcctgttgtt gattgttcat gatttcctcc cattagaaat ttattttata
     1441 tataaataat attatcacag aaaactttaa aagaaaacgt tttatataat atagacaata
     1501 gattatattt ttataaagaa gcaagaatac tcaataaaac ttaaagaaat taaacaattt
     1561 ctaaaaatac cttgaaaata gaaccttatt tgccatttat aaattatata aaaagggatt
     1621 atataaagtc atatatgaaa aaactatatt atactatctt ttctttttgg aataaactat
     1681 actttaaata tagatattta atttaaataa attttacagt attaatagta aattatctta
     1741 gaaaggaatg tgctttatat gtctacagac aaagttgttg gaatcataga tgaagaaacg
     1801 gcagaacttg caggaattga atatactggt aaaatttatg cttcttctgg tgttataaaa
     1861 catataaaga aaaaacatag atgtcaactg agtaaggata tttttaatga tataatagac
     1921 actataaaag tggtattaaa gtcacctgaa tatataggaa gtcatcctaa aaaacctgga
     1981 aaaagtgtgg agtttataaa aaaaattgat aattatattt tagtagctac agaattagat
     2041 acaaaaaaag gatatttata tgtatcttca atgtatgcta taaaagaagc aaaattagaa
     2101 agtagagtaa acaatggaag agtaaaacaa tatgatggtt aacataatat tattaatttt
     2161 ccccaaaata ttgaaaaata ttattatata agttataata ttaatataca cgtagatatt
     2221 tattagttag atttgaggtt ggaaaaggca cccaatacgc tactatagag tagttaatag
     2281 agatgcagga tacgccgccc tgccaaatct aattaaatta aaaagagagg attaattcct
     2341 ctctttttgt ttttttgaga tactaattta atctatatag aaagattgaa ggtcatttat
     2401 actaaaagtt ttcagttata tacattaaac taattaaata agata
//
LOCUS       DAMJWO010000179         2444 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.185, whole genome shotgun sequence.
ACCESSION   DAMJWO010000179 DAMJWO010000000
VERSION     DAMJWO010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2444
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.185"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            92..565
                     /locus_tag="PC366_003667"
     CDS             92..565
                     /locus_tag="PC366_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDF2579147.1"
                     /translation="MFKEYLIRELKEDDIKNALDLIWNVFEEFESPDYCDEGITTFHQ
                     FIEYNSIIEKIKEKTLFFWGCFDSKKLIGVLAIRNLNHICMLFVDKNYHKHGVAKKLM
                     TTGIQYCICNKFNLTEITVNSSPYAVEVYHKLGFEDIAVEQIVDGIRFTPMKLLI"
     gene            complement(934..1491)
                     /locus_tag="PC366_003668"
     CDS             complement(934..1491)
                     /locus_tag="PC366_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDF2579148.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAEKLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNSQMIKATIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSLL
                     SKEEAIKGLADSIDTVLLGIHKKYD"
     gene            1749..>2444
                     /locus_tag="PC366_003669"
     CDS             1749..>2444
                     /locus_tag="PC366_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDF2579149.1"
                     /translation="MEKKYFEIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPHEYQVLSVDLPEHGERKREKNSFNPWHVVPELVSIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPITQWNVPTKILYGKHDELTEIGVVEKFVEKFNCNLTILENGKHWFNTPQ
                     ELNSLYEWLNTLVK"
BASE COUNT          901 a          318 c          305 g          920 t
ORIGIN      
        1 taaatttata aaacaaattg tattgaatta aatttattta agatatataa ttataattat
       61 aattaaaata ataataaagg tgttgtttat aatgttcaaa gaatacttaa taagagaatt
      121 aaaagaagat gatattaaaa atgcattaga cttaatctgg aatgtatttg aagaatttga
      181 atctccagat tattgtgatg aaggaattac gacatttcat caatttatag aatataattc
      241 tattattgaa aaaatcaaag aaaaaacact cttcttttgg ggttgttttg actctaaaaa
      301 acttattgga gtcttagcta ttagaaattt aaatcatata tgtatgttat ttgtagataa
      361 aaactatcat aaacatggtg ttgcaaaaaa attaatgact acaggcatac aatactgtat
      421 ttgtaataaa tttaatttaa ctgaaataac tgtaaattca tcaccttatg ctgttgaagt
      481 ttatcataaa ttaggatttg aagatattgc tgttgagcaa attgttgacg gtatacgttt
      541 tacacctatg aaattgttaa tataataaat taaataaaaa gcaaagtctc ttaaatattt
      601 tatagttact ttgcttttaa accaagattt aaaataatac tatctttttt gttttttaat
      661 aatatacttt aaaagcctta ctaatatgaa ctataattta ttttttgata tcctttttga
      721 ttaacatata aattaattca attattaaac ataaactatg ttgtttctct ttatatctct
      781 tctttgtaaa caatattggg catttgaaaa taaatattct taaaatatac tgttctcctg
      841 ttgattttcc tttggtacaa atgataaaat tttaatttac atgctccgta atgaagtgtt
      901 taataaataa gttaaaataa tttatttacc tccttaatca tattttttat gaatacctaa
      961 taacacagta tcaatagaat cggctaaacc ttttatagct tcttctttac tcaaaagtga
     1021 tttcccaagt tgcaaagtcg aataaccatg aagtacactc attattaagt ttaatacttc
     1081 acctgtattc tttgtattta gattacaaga aagaataagt ttttctaata aggatttata
     1141 ttcatcaaag atttctaatg tttcattatt tccatgccaa gtagcccact gaattgtttc
     1201 ataaacacca ggattagaaa ttataaaatt aaagtatgct atacttatac actttatagc
     1261 tgtatctcca aaatttccaa tagtcgcctt tatcatttga ctattcatct ctctcattcc
     1321 tttatgagct acttcaagta ataaatcatc tagactttct atatgattgt acaaagatgg
     1381 tgtacgtatt cctagctttt ctgcaataac ttttaaagaa actttgttaa gcccatcttt
     1441 attaactata tctgatgtag cttgtataac tatttctcta ctaacacgca tgattttccc
     1501 tctttcattt aaaattaatt actttattag tttagctaat ctaattagtt tcgtcaatta
     1561 ttgtaattta taaaattctt tatactctta taaaatcttg acagtttaat tataatttaa
     1621 tataatacta attgaattag ttttaatact aatataatta gtattatatt aaattatata
     1681 ttacaacatt attttatagt ttgattaatt caacaatcac taatatatca aactgaaagg
     1741 agatttttat ggaaaaaaaa tatttcgaaa ttcatggagt tccttcaatc ctttggggaa
     1801 atccttcaag taaattatat atttacatac atggacaatg cggcaataaa gaggaggctg
     1861 aagcttttgc taatattgca gttccacatg agtatcaagt tttaagtgtt gatttgcctg
     1921 aacatggaga acgtaaaaga gaaaaaaatt catttaaccc atggcatgtt gttccagaat
     1981 tagtatctat tatggaatat gcaaagtgcc actggaatca aatttcgtta tatgcaaata
     2041 gcattggagc atggtttagt atgttaagct ttgaaaaaga gaacttaaga gagtgtattt
     2101 ttgtatctcc aattctagat atgcaacagc tcatttcaaa tatgatgctt tgggcaaatg
     2161 tatcagaaga acagcttaaa catgaactaa ttatcccaac ttcatttggg catactcttt
     2221 catgggaata tctacaatat gtaaaacaac atcctatcac tcaatggaat gtaccaacaa
     2281 aaatattata tggtaaacat gatgaactta ctgaaatcgg tgttgtagag aaatttgtag
     2341 aaaagtttaa ttgcaacctt actattctgg aaaatggcaa acattggttt aacacaccac
     2401 aagaattaaa ttcattatat gaatggttaa atactttagt taaa
//
LOCUS       DAMJWO010000180         2417 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.186, whole genome shotgun sequence.
ACCESSION   DAMJWO010000180 DAMJWO010000000
VERSION     DAMJWO010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2417
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.186"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            272..412
                     /locus_tag="PC366_003670"
     CDS             272..412
                     /locus_tag="PC366_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579150.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
     gene            complement(409..780)
                     /locus_tag="PC366_003671"
     CDS             complement(409..780)
                     /locus_tag="PC366_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2579151.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTKISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
     gene            1329..1586
                     /locus_tag="PC366_003672"
     CDS             1329..1586
                     /locus_tag="PC366_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579152.1"
                     /translation="MIIIRSQDKTNLMQINQIKIDGSQVYAVFESKIDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITSNKVRYNVNKIFQMPAK"
     gene            complement(1696..2376)
                     /locus_tag="PC366_003673"
     CDS             complement(1696..2376)
                     /locus_tag="PC366_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDF2579153.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVMIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSGLFRIDEINLIPFDSVGILTYILNIIMFMPLGFLL
                     PLIWKNFRNIINVSLTGLGFSLAIELCQLFNLRATDIDDLMMNTLGAVLGYFIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISKKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
BASE COUNT          977 a          267 c          278 g          895 t
ORIGIN      
        1 tttataataa aaatcatcct gaaaaatata taaaaataga aaaaacatac aagattctac
       61 aataatagat ttttttgtta ttattacgag ttttttattg caactgtaga ataaaagtat
      121 tattatataa ttaagataat tatctaggga aattttggat aatcaaaata tattttataa
      181 aatcaaaata caattacata aactttatta aaaatttgtt gggaatttct gactagcatt
      241 aagaacgtaa gtttgttggg ggatggtata tgtggaaaag tcaaacacta ctgttacaaa
      301 aaaagaaaaa attgaagata taggaatgaa attagaacat ttattgagtg aagatattac
      361 tttttatgaa ttattacttg agattttgta taaagaaaaa gaagagaatt aattctcttc
      421 tttaaggaat ctttttaaat aggcattatc aatcattttt tctatagctt ctctatcttc
      481 tttttcaaga gaatatattt tttctaagag cttttttgtt ttttcactta ctgataagtt
      541 ctctatgatt aatttatctt ctttgcttat ttttgtatta tcatttacgc ctaataaata
      601 atctgttgat gtttctaatg cttttgctaa tctaactatt atttcacttt taggttctct
      661 taaattattt tcataacgtg acaagctagc ctcagttata ccgactttag tagcaagttc
      721 tttttgattt atatctaatt cttttcgtag atttgctatt ctatctccta aactttccat
      781 atgtacatca ctccttaccg aaattataag ttattttgat aaaaagtaaa ataaaattac
      841 caaaaatata aaaaaaaagg gttaaaataa taaaatatat tgaaaattac catttgtata
      901 tgtataatat gaattataca aatggtaatt tgatgagagg tggtatgttg aaataagaaa
      961 ctgaattaat taataaatat atagaaagtt ttgaaaaccc ttaattgaga tataaacaat
     1021 atgtacaaaa ttttttgcaa gtaaaattac caaatgtata aaataaatca gtagcataga
     1081 taattttatg ctttaataca ttagattatt taatttagtt ataatggtca aaaatgcaat
     1141 ctacaaataa aacaaagtat tatcaaaaaa gtattcttta agagaatttt ttattagaga
     1201 tgtaatttat ataaataatc gtattaaaaa ataaaatact aagtttaaaa atttaaataa
     1261 tctataaatc aattataaaa tattatttct tagaaattaa aatgaattaa gtaaatggag
     1321 gaattgatat gataataatt agaagtcaag ataaaactaa tttaatgcag ataaaccaaa
     1381 ttaaaataga tggtagtcaa gtttatgcag tatttgaaag taaaattgat actgtaaaaa
     1441 taggagatta tgaaaataat acaagagcta tacaagtgtt ggacaatata caaaacttca
     1501 ttgaaaatgg aacaaaatat gattatataa catcaaataa agtcagatac aatgttaata
     1561 aaatatttca gatgccagct aaatagtgag tgtgcatttt agtttaataa ctaaagccca
     1621 ctttcttttg tagtatgaaa gagggcttta catatttgta aatatcgaag tacacttgtt
     1681 ttatcaataa attatttaat aaggtataat ggaccaatta aacaataaaa attctcctaa
     1741 aacagcaagt attaaatata taatagcttc atttttgtaa agagaggtaa tttttttgct
     1801 tatgtcatca tcaattgtaa tagcaatttc atcttgaata atatttttat atatagatgg
     1861 gaaaatatct tttttcttta taagattaaa taaattattt acacctaccc atataaaata
     1921 tcctaaaaca gcacctaatg tgttcatcat taaatcatca atatctgtag ctcttaagtt
     1981 aaacaattga caaagttcaa ttgctaatga aaaacctaat ccagttaatg aaacattgat
     2041 aatatttcta aaatttttcc aaattaaagg tagtaaaaat cctaaaggca taaacataat
     2101 tatatttaaa atatatgtta agatgccaac tgagtcaaaa ggtattagat ttatttcatc
     2161 aattctaaaa agcccactat accttcctat atcccatatg ctaccaattc cagctttact
     2221 aagtgctaga tagatatata ataaaaaaat atatacccat actaaatgta tcattacatt
     2281 cttttcaact ttcaaatttt ttcgttttat aacgactatt tggtatatta agcatggtaa
     2341 tataacgcaa ataaatgaat aaaatgtcca tatcatttta ttttgtcccc tttcaaattt
     2401 atgtttttag ttttata
//
LOCUS       DAMJWO010000181         2397 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.187, whole genome shotgun sequence.
ACCESSION   DAMJWO010000181 DAMJWO010000000
VERSION     DAMJWO010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2397
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.187"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(84..995)
                     /locus_tag="PC366_003674"
     CDS             complement(84..995)
                     /locus_tag="PC366_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HDF2579154.1"
                     /translation="MSRAERLIELMITINAKRSFTAGELAEEFSVSKRTILRDLQVLE
                     SVGFPLYSKVGAAGGYHVLKERILPPITFSESEVKSIFFAYQSLEYYNDLPFEQETIS
                     VLKKFLNCIPNDIQYNIENMRRKLVFWTPDRHCSTPLLKELFNIVMNEFTIKIEYSSK
                     QKNSIRTIVPIGLYAMNGLWYCPAYCIKSESVKEFRADRIVKILSIENLSNKKYKVLS
                     SIHDYLKNMEVGTDYHIKINLTDEGVKRCETEFLLARGLKILSKGGYIDMYIPKSTLN
                     WVAEYFLTFGKNATIIEPIELKHLIKK"
     gene            1106..1573
                     /locus_tag="PC366_003675"
     CDS             1106..1573
                     /locus_tag="PC366_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579155.1"
                     /translation="MENDTIKADDILNYCLSNLDDVVLMDSWGERAIYYNPNGVLKRG
                     VYVLTIKEKDSNHDKGSLVSRPNVYRVNIGLKKETFIEMFGYIPKRPGVGQIVDMDFD
                     FTKLDTIMPHPIYSWMGWICVLSPTEKTFENFKTLIEESYNFAKQKFKKRKNK"
     gene            complement(1741..2340)
                     /locus_tag="PC366_003676"
     CDS             complement(1741..2340)
                     /locus_tag="PC366_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579156.1"
                     /translation="MKLKRTLFVGLALVLAIGITACARDNEKPNENAGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKRMNDDLIAEGERLVKDIDERIEKLDKVSDEDMKKGQN
                     DFMKLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
BASE COUNT          805 a          400 c          281 g          911 t
ORIGIN      
        1 ttatcctatc tctacatata agtttcccta tatgctgact aatttagcta ctaactcatg
       61 actaaagtca caagtgtgcg tagctatttt ttaatcaaat gtttaagttc tataggttct
      121 attattgtag cattttttcc aaaagttaaa aaatattcag ccacccaatt aagtgtagat
      181 tttggtatat acatatctat gtatccaccc ttagacaaaa ttttcaatcc tcttgccaac
      241 aaaaattctg tttcacaacg ttttactccc tcatctgtca gattaatttt aatatgataa
      301 tctgtaccta cttccatatt cttaagataa tcatgtatag aagataaaac cttatatttc
      361 ttatttgata agttttctat actcaaaatc ttcacaattc tgtctgcacg aaattcctta
      421 acagattctg attttataca gtaagctgga caataccaaa gtccattcat agcatacaaa
      481 ccaataggaa caatggtacg tatactattt ttttgctttg atgaatattc aattttaatt
      541 gtaaattcat tcattactat attaaacaat tccttcaata atggtgttga gcaatgccta
      601 tctggtgtcc aaaaaacaag tttacgtctc atattctcaa tattatattg aatatcattt
      661 ggtatacaat ttaaaaattt ctttaaaaca gaaatagttt cttgctcaaa tggtaaatca
      721 ttataatact ctagtgactg atatgcaaag aatatagatt ttacctcact ctctgaaaat
      781 gtaattggtg gaagtatacg ttctttaagt acatgatatc ctccagccgc tccaactttt
      841 gaatatagtg gaaatccaac actttccaat acctgtaaat ctcttagtat agtacgtttt
      901 gatacagaaa attcttctgc tagctctccc gctgtaaaac ttctttttgc atttattgtt
      961 atcatcagtt caattaaacg ctcagctctt gacatattca tactcctaat ttaaatatag
     1021 tgacaataat tgtcaccatt atatgataag atattcttgc atctaaagca ataataatat
     1081 taaagaaaga agggattgat attttatgga aaatgatact attaaggctg atgatattct
     1141 caattattgt ctatcaaact tagatgatgt tgtactaatg gatagttggg gggaacgagc
     1201 aatttactac aatcctaatg gtgttttaaa gcgaggggta tatgttctta ccattaaaga
     1261 aaaagacagt aatcatgata aaggttcgtt ggttagtcgt ccaaatgtat accgtgtgaa
     1321 tataggatta aaaaaagaaa cttttattga aatgtttgga tatattccaa agcgtccagg
     1381 tgtagggcaa atagttgata tggattttga ttttacaaaa ttggacacaa tcatgccaca
     1441 tcctatctac tcatggatgg gatggatatg cgtcctaagc cctactgaaa agacatttga
     1501 gaactttaaa actttaatag aagaatctta caattttgca aaacaaaaat ttaaaaagag
     1561 aaaaaacaag taaaaacata aaaaaataac ctctaaataa actataatga aaatatgagg
     1621 ttacaagata aaaattagta tcttgataac atacaaaaaa gcgaagccaa aaaatatatt
     1681 aattacaagg cttcgctata tttcaaatat ttatttctaa ctttaaaact atttactcta
     1741 ttatttttta ttatttcctg ttattcccaa tctatcattc atatctttta tcatttttct
     1801 aaaaccacta ccaatatcgt ttccaacatc ttcagttcca tgaactagtt tcataaaatc
     1861 attttgacct tttttcatat cttcatcaga taccttatct aatttttcta ttctctcatc
     1921 tatatctttt actaatcttt ccccttcagc tattaggtca tcattcattc tctttaactc
     1981 tgtatcttct gttttaccgt cttttttaag agatgttaca aatgattgta ttttatctct
     2041 actatcttta tatgcagcct ttacatcact tagatatttt tcatttcctg gatattcttt
     2101 atctttaaac tgattgttta tactttctgg agtatcataa atagaatatc tatttagacc
     2161 tgctatataa tcattataac ttgttgaata ataattcata tatccttcat tattatttac
     2221 agattcatta ggattttttc ctgcattttc atttggtttt tcattatccc tagcacatgc
     2281 agttattcct atagctaata ctaatgctaa tcctacaaat aaagttcttt ttaatttcat
     2341 ttttattacc ctcctagatg ttttgtacta caaaaaattt taataatttt ctttctt
//
LOCUS       DAMJWO010000182         2374 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.188, whole genome shotgun sequence.
ACCESSION   DAMJWO010000182 DAMJWO010000000
VERSION     DAMJWO010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2374
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.188"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..344
                     /locus_tag="PC366_003677"
     CDS             <1..344
                     /locus_tag="PC366_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2579157.1"
                     /translation="IKENDIICIEDLQVKNMIRNRKLSRLISDVSWSEFVRQLEYKAN
                     WHGRQIVKVGKFFASSQICNKCGYKNEEVKDLNIREWICPSCNEIHDRDINASINILK
                     EGLRLITIQNK"
     gene            628..1074
                     /locus_tag="PC366_003678"
     CDS             628..1074
                     /locus_tag="PC366_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HDF2579158.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESI
                     FLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVDATVNVTNQ"
     gene            1095..2138
                     /locus_tag="PC366_003679"
     CDS             1095..2138
                     /locus_tag="PC366_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HDF2579159.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEVLD
                     IKEVLNDNESLKK"
BASE COUNT          973 a          247 c          447 g          707 t
ORIGIN      
        1 taataaaaga gaacgatatt atttgcatag aagatttaca agtaaagaat atgattagaa
       61 atcgtaaact atctcgctta atttctgatg tgtcatggtc agaatttgtt cgtcaattag
      121 aatacaaggc taattggcat ggtagacaaa ttgtaaaggt aggtaaattc tttgcaagtt
      181 cacaaatatg caataaatgt gggtataaaa acgaggaagt gaaggactta aatataagag
      241 aatggatttg tcctagttgt aatgaaattc acgatagaga tataaatgca agtataaata
      301 tattaaaaga aggattaaga ctaataacga ttcaaaataa ataacttatg taagaaccgt
      361 aggaactacg gggatagcct gtggagaatt agtaagacat atgttagtat gcaaaattct
      421 atgaagcagg aaccctgtga ctttagtcat gggaggttca gactactttg taacaatttt
      481 aacaaagtat gttgatataa tactattaaa ttaatcttag attagtttat tctattgatt
      541 tgtagtttaa atttatattc aaaaacattg tataaacata taatttatat agggttttat
      601 aattcatatg aaaagagggt agatagtatg aagttaatat ggttgatagt agcagtctta
      661 tttggaatag cagaaatgtt aacaccaagc ttaacattga tatggtttag tgtaggagct
      721 gtaatactta tatttttaag tagctttata gagagtattt tcttacaaat tttaatattt
      781 gcagtaattt ctatagcaat gttagtcgta gctactaaaa aaatagtaaa aaaagataaa
      841 ggctataaat ctaacactaa tttacaagca atgatgtcta aaaaaggtat tgttacagaa
      901 gagatttctc caaataacac aggtctagtt gtagttgaac atgaaacatg gacggctatt
      961 tctatagatg gtgaaaagat agaaaaaggt tctacagtag aagtattaaa aattgaaggg
     1021 gtaaaattag ttgttaaaaa agtagacgcc acagttaatg tgacaaacca atagaataaa
     1081 ggaggattta tagtatgggt actaaaattg ttttaagtat tgtattaata gtagtagtcg
     1141 tagcaataag tttaacgtgt ataagagtta taaaacaatc taaagtaggt ataataatga
     1201 gacttggtaa gtttcaaaaa gtggctgaaa caggtgtaca tttcttaata ccatttttag
     1261 ataaaatggc atatgtaatt gaccttagag aaattgtaat agattttcca cctcaaccag
     1321 ttataactaa agataatgta actatgcaga ttgatacagt tgtatattat aaagttacag
     1381 atccagttag atatgtgttt gagatagcta atccaatagc tgctattgaa aatttaacag
     1441 ctacaacact aagaaatata attggtgaac ttgatttaga tgaaacatta acatcaagag
     1501 atataataaa tgtaaaaatg agaactatcc ttgatgaagc aacagataaa tggggtataa
     1561 aagtaaatag agtagagtta aaaaatataa tgcctcctca ggatattcaa gttgcgatgg
     1621 aaaaacaaat gagagcagaa agagaaagaa gagaggcaat acttcaagca gaaggtaata
     1681 agtcagctgc aatacttcaa gcagaaggtg aaaaacaatc tgcgatatta acagcagaag
     1741 ccaaaaaaga agctatggta cgtgtagcag aaggtgaaaa agaatctgct atattagtgg
     1801 cagaaggtga agctgaagct ataagacaga ccgctattgc taaggcacaa ggtgaggctg
     1861 aaatgataaa aagaactcaa atggcaacag cagaaggttt aaaattagtt ttttcagcaa
     1921 tgaaagaggc tgatatagac aataatattc tagcattaaa atctatggaa gctcttgaaa
     1981 aaatggctga aggtaagtca acaaaactgg ttttaccttc agaagcagtt aatttcctag
     2041 gaacattcaa aggaataaag gaagttatga gtgatgataa caaagaagta cttgatataa
     2101 aagaagtttt aaatgataat gaatcattaa aaaaataaaa gagttttgtt atcataggaa
     2161 ggatatggaa attaaaggtc gaattaatta aatatagcac aaaaatgcac gttgaaaaga
     2221 agaggactta taaattttta agtcttcttc tttgttttta ttagaaagat gaaattataa
     2281 aaatgaatta acagaatctt tatacaattt atcctttact aatgtaaaaa gtgttatata
     2341 atattatata aaacatatag caaataagca tggt
//
LOCUS       DAMJWO010000183         2297 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.189, whole genome shotgun sequence.
ACCESSION   DAMJWO010000183 DAMJWO010000000
VERSION     DAMJWO010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2297
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.189"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(182..1474)
                     /gene="brnQ"
                     /locus_tag="PC366_003680"
     CDS             complement(182..1474)
                     /gene="brnQ"
                     /locus_tag="PC366_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDF2579160.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLI
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFSRAGKGLSIALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIVSPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     EKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIKFSSPILSMVYPATITLVILALFSNKIKNDNVFKCAAYMALLVSVLTVATSFGVK
                     IPLVNSLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
BASE COUNT          775 a          386 c          246 g          890 t
ORIGIN      
        1 aattataaat aaatcttttt tattttattg tctttataaa tcatactcct ccaaaaataa
       61 atttatcaaa tgagattaat aatgttcttt tctccacaat aatttaataa ttcttttaaa
      121 tataaaaagg aattgccata taatttaaag gcaattccac aattatcaat tagttttatt
      181 attatgcagt tttactgctt ttagatggaa taaagtttcc tattattcct gctattacaa
      241 ctggaactat ccagttaaat cctaatgaag caaatggtaa gctattaact agaggaattt
      301 ttacaccaaa acttgttgca actgttaata cacttactaa taatgccatg tatgcagcac
      361 atttgaacac gttgtcattt ttaattttat tactaaataa tgctagtata actagagtta
      421 tagttgctgg atataccata cttagtatag gagaagagaa ttttattatt gtacttactc
      481 caaagtttga tatgattgca ctaaatacac aaactactat aactatatgc tcatacttta
      541 attttccatc tgtaagtgtt gagaaatatt gaccagctgc tgaagaaaga cctatagctg
      601 ttgttaaaca tgctaatgca actataatag ccaataaaat tttacctgta gttccaagta
      661 aagctgctgt tattgcaact attaaagctg tttgttgaac atcttgtcca tattgttgag
      721 acacagttgc tccaagataa cataatccac cataaactaa tgccattcct attactgcaa
      781 ttacacctgc acttattgtg gctttcatct tttctttctc acctgtataa cctttagcta
      841 ttactgacat gattataatt gatgcaaata cactagctgc caatgcatcc attgtttgat
      901 aaccttgagt tataccttct gcaaatacat tttgaattaa agaactgtct cttatttctc
      961 ctaatggaga tacgatacct ttaactatta atactgctaa agctataagt aaagctggag
     1021 ttaatattga cccaactata tctacaactt ttgatggtct tattgttaaa accaatacta
     1081 gagcaaagaa tactatagag aatattactg gacttattcc agaacctatt gtaggcaata
     1141 tacccatttc ataagttgtt gctgctgttc taggtattgc taaaagtggc cctatacaga
     1201 ttaccattgc acatcctaat gcaatactta atcctttgcc tgctcttgag aacatcttcg
     1261 atgtgtctcc attgaactta gttgctgcta taactgctaa taatgccaaa ccaccatctg
     1321 caaaaaggaa tcctatgaaa gctattagcc aactacttcc agataaaact cctagatatg
     1381 gagggaagat taagttccct gcaccaaaaa acattgcaaa tagtgcaaat ccaattacaa
     1441 ttacatcttt aaaattgatt tgtttctcac ccatttaaag cacccccatt tgaattttac
     1501 taccttttac taaaaaataa gtccaatctc ttcattaaat gaaaaccttt tgacgagatt
     1561 ttatttaatt atacattttt gacttaaatt tgtcaattat gtttcataat ttataaaatc
     1621 ttcacaatat ttaatacaac tttcttaatt aaacaaaatc aacctgtata ctttaaacat
     1681 agttggtttt ttgttttttc tctaattttc cttgataaaa ttaactattc agaacaatta
     1741 aaatattaag actttttaga ttattcgttt tattattaag ttgtattgct ttatatactg
     1801 tatatatcac tctccttttt acattcatat aatcttttta attcaattta aattttaaat
     1861 attttgtgtt tattatataa tctgaaaaaa aagcagtcaa tagcattttt aattttttta
     1921 attttcaaaa ttatgattct taaaaaatcg ttttcctttt atcataacac ctattaacgt
     1981 taattcttgt agtattttgt atttattttg ctaaattgac agttaacttt attcaatttt
     2041 tattctactc acgtagattt acctcttgtc ttttagtctt aaaaccattt tttctgaaaa
     2101 ttccttatta tgatttatca acttattttt cttcatagca attactttct aacttccaac
     2161 ttacttaaac tttgcagttg ctagtattca cgtttacata cttatatgtc ataattaact
     2221 aaaaattctt aatatatctc tcaatgaaaa caatttactc atttatttaa tacatttata
     2281 taatcatatg tcttaaa
//
LOCUS       DAMJWO010000184         2033 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.190, whole genome shotgun sequence.
ACCESSION   DAMJWO010000184 DAMJWO010000000
VERSION     DAMJWO010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2033
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.190"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            140..538
                     /locus_tag="PC366_003681"
     CDS             140..538
                     /locus_tag="PC366_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579161.1"
                     /translation="MNKKKKLIGIAISFLLIISIINPLQVEAEAIIESSVYISSIKEN
                     YTYDNTKFKTIKSKSRHKSRKYNKSKVKLKKRSIRTKKYGYQTINKYKRRNARRHNIL
                     TKLVLSIIVIFLVIVLVVLIFIKRKKKKFY"
     misc_binding    974..1237
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1388..1939
                     /locus_tag="PC366_003682"
     CDS             1388..1939
                     /locus_tag="PC366_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HDF2579162.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNRDDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMNISYNMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
BASE COUNT          866 a          186 c          302 g          679 t
ORIGIN      
        1 ttttaaaaaa agtaaaagtt atgataataa aaataatatt aaagataata agatatataa
       61 gaaacttgaa aaaatttgta atttttagtt atatatatat tataatgaac tagttaaaaa
      121 tttttatgag ggggaaaata tgaataagaa gaaaaaattg attgggatag ctatatcttt
      181 tctacttata atcagtatta taaatccatt acaagtagaa gcagaagcta ttattgagtc
      241 tagtgtatac atttcttcaa taaaagagaa ttatacatat gataatacta aatttaaaac
      301 tattaaatct aaaagtagac ataaaagtag gaaatataat aaaagtaaag taaagttgaa
      361 aaaacgaagt ataagaacta aaaagtatgg atatcaaact ataaataaat ataaaagacg
      421 aaatgcaaga agacataata tcctaacaaa attagtattg tccataatag tcatattttt
      481 ggttatagtt ttagtagtgc taatatttat taaaagaaag aagaaaaaat tttactaaaa
      541 ataattaaaa gaatatcatt tttctaatca ttggtatcta tttaataata tgatgtaatt
      601 aaaatggagt aatattctgt ttcaaaggag gcatataaat acaggaatga gtattaaatg
      661 atggttaatt aagtaaattt attgataaat gtacttaatt aactttgaag aatttaattc
      721 ctcatgaatc aaaatataaa attacatcaa cagttattca caaaattaat ataagaagaa
      781 ttagagccaa agagcagact attagaccat taaagtaatt attcatagaa ttttgtatat
      841 gaaaagaaat gtatagtata atttactttt tttataaaaa atagattaca aaatatattt
      901 tttataaaaa ggtattgaca ttttttagaa aaaagaatat cattatttta acaacaaaat
      961 tcaatacaat aaattaaatc ctatgacaag gaagagtagt taaatttagg ttcagtatag
     1021 agagctgagg atggtggaat cttagcaaga aaaaatttga tgaatggccc ttagaggaat
     1081 aaattgaaat catagttttg agagtagact ttatcgtcag tcgcacgtta tagcgaataa
     1141 ggtatgtaag tacctgataa tgagatgtat gaaaattgaa ttttatatta atttttatat
     1201 aatttaggtg gcaacgcgga taatctccgt cctattagtt taggacggag ttttttattt
     1261 tactgaaaat ttaaaagata gaaggtggtg agaaagatgt tatgaatttc aaaagctaaa
     1321 gatgatgata tagtaggttg gcaaaaaaat aaattgaaaa ttaaaaaaat aggaggaagt
     1381 acaaaaaatg aaaacaaata caaaaaaatt aactttaaat gcaatacttt tagcgatggg
     1441 attattaata catcaaatca caccagctat aggattacca atgaagccag atgtaccact
     1501 agcaatgtta tttgtaatat tggttttaaa tagagatgat tataaaactt gtttgatagc
     1561 gggtatagta acaggaatat ttacagcact tacatcaagt tttccgggag gtcaaattcc
     1621 taatgtaata gataaaactc ttacagcaaa tatagtattt ttattaatga atattagtta
     1681 taatatgcct tttataaaaa aattagctaa gaaaacacaa gatactgtag tagttgcaat
     1741 aataatgcca ataggaactc ttgtaagtgg aactatcttt ttattagcag ctcaagctat
     1801 agttggtctt ccaggagctt catttacagc tttattctta gcagtagtat taccagctgt
     1861 tttaataaat ctagttgcag gaatattttt attcaagatt gttagtctat caataagaag
     1921 agttagttat caagcttaac tacgaaataa tattttactt tataaagcat tataataact
     1981 aaataacata agaataaagt agattataac tattttattc ttatgttgtt taa
//
LOCUS       DAMJWO010000185         1983 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.191, whole genome shotgun sequence.
ACCESSION   DAMJWO010000185 DAMJWO010000000
VERSION     DAMJWO010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1983
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.191"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            178..294
                     /gene="rrf"
                     /locus_tag="PC366_003683"
     rRNA            178..294
                     /gene="rrf"
                     /locus_tag="PC366_003683"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            301..375
                     /locus_tag="PC366_003684"
     tRNA            301..375
                     /locus_tag="PC366_003684"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:333..335,aa:Asn,seq:gtt)
     gene            380..454
                     /locus_tag="PC366_003685"
     tRNA            380..454
                     /locus_tag="PC366_003685"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:413..415,aa:Glu,seq:ttc)
     gene            460..535
                     /locus_tag="PC366_003686"
     tRNA            460..535
                     /locus_tag="PC366_003686"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:493..495,aa:Val,seq:tac)
     gene            541..617
                     /locus_tag="PC366_003687"
     tRNA            541..617
                     /locus_tag="PC366_003687"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:575..577,aa:Asp,seq:gtc)
     gene            628..702
                     /locus_tag="PC366_003688"
     tRNA            628..702
                     /locus_tag="PC366_003688"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:660..662,aa:Thr,seq:tgt)
     gene            717..801
                     /locus_tag="PC366_003689"
     tRNA            717..801
                     /locus_tag="PC366_003689"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:751..753,aa:Tyr,seq:gta)
     gene            811..884
                     /locus_tag="PC366_003690"
     tRNA            811..884
                     /locus_tag="PC366_003690"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:843..845,aa:Gly,seq:tcc)
     gene            895..971
                     /locus_tag="PC366_003691"
     tRNA            895..971
                     /locus_tag="PC366_003691"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:929..931,aa:Arg,seq:tct)
     gene            981..1056
                     /locus_tag="PC366_003692"
     tRNA            981..1056
                     /locus_tag="PC366_003692"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1014..1016,aa:Gln,seq:ttg)
     gene            1068..1143
                     /locus_tag="PC366_003693"
     tRNA            1068..1143
                     /locus_tag="PC366_003693"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1101..1103,aa:Lys,seq:ttt)
     gene            1146..1234
                     /locus_tag="PC366_003694"
     tRNA            1146..1234
                     /locus_tag="PC366_003694"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1180..1182,aa:Ser,seq:tga)
     gene            1252..1342
                     /locus_tag="PC366_003695"
     tRNA            1252..1342
                     /locus_tag="PC366_003695"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1286..1288,aa:Ser,seq:gct)
     gene            1351..1427
                     /locus_tag="PC366_003696"
     tRNA            1351..1427
                     /locus_tag="PC366_003696"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1385..1387,aa:Pro,seq:tgg)
     gene            1513..1588
                     /locus_tag="PC366_003697"
     tRNA            1513..1588
                     /locus_tag="PC366_003697"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1546..1548,aa:Trp,seq:cca)
     gene            1649..1725
                     /locus_tag="PC366_003698"
     tRNA            1649..1725
                     /locus_tag="PC366_003698"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1683..1685,aa:Pro,seq:tgg)
     gene            1732..1808
                     /locus_tag="PC366_003699"
     tRNA            1732..1808
                     /locus_tag="PC366_003699"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1766..1768,aa:Ile,seq:gat)
     gene            1812..1887
                     /locus_tag="PC366_003700"
     tRNA            1812..1887
                     /locus_tag="PC366_003700"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1845..1847,aa:Phe,seq:gaa)
     gene            1895..1971
                     /locus_tag="PC366_003701"
     tRNA            1895..1971
                     /locus_tag="PC366_003701"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1929..1931,aa:Met,seq:cat)
BASE COUNT          501 a          449 c          535 g          498 t
ORIGIN      
        1 aatgtattta gcttatcgat actaataggt cgaggacttg accaatatta tttgatgtta
       61 ttcattaaga tatatgtgca gtttttagag tgttaactct aaaaaaaaat aaaaaaagta
      121 ttgacaaaaa tagtaaaaaa tgttaatatt atacttgtcc tagcaacaag aaaaaaatgt
      181 ggttataata gcagagaaga tacacctgtt tccattccga acacagaagt taagttctct
      241 agcgctgatg gtacttggtg ggaaactgcc tgggagagta gggcatagcc acgtgaatgt
      301 tccaaggtag ctcaacggtg gagcaaccgg ctgttaaccg gtaggctgtg ggttcgagcc
      361 ccacccttgg agccattatg gctcgttggt caagaggtta agacaccgcc ctttcacggc
      421 ggtaacaggg gttcaattcc cctacgagtc accatttgtg ggatcatagc tcagctggga
      481 gagcacctgc cttacaagca gggggtcaca ggttcgagcc ctgttggtcc caccatttgc
      541 ggcctggtag ttcagttggt tagaatgcca gcctgtcacg ctggaggtcg agggttcgag
      601 ccccttccag gtcgccaaaa taaaaatgct ggtgtggctc aacggtagag cagctgactt
      661 gtaatcagca ggttgtaggt tcgattccta tcaccagctc catgtaaaac taatacggag
      721 gatttcccga gcggccaaag ggggcagact gtaaatctgt tgtcatcgac ttcggtggtt
      781 cgaatccacc atcctccacc aattaaatat gcgggtgtag ctcaatggta gagttctggc
      841 cttccaagcc agctgtgagg gttcgatccc cttcacccgc tccaaagaaa gcgtgggtgc
      901 atagctcagc tggatagagc aacgcccttc taaggcgtgt gtccggggtt cgaatccctg
      961 tgcgctcacc acatatatat tggggattag ccaagtcggt aaggcacatg actttgactc
     1021 atgtatgcgt aggttcgagt cctgcatccc cagccaaata aaaatatggt ctattagctc
     1081 agtcggtaga gcacctgact tttaatcagg gtgtcccgcg ttcgagtcgc ggatagatca
     1141 ccaatggaga ggtgtccgag tggtttaagg agctggtctt gaaaaccagt gacttcgaaa
     1201 ggggccgtgg gttcgaatcc caccctctcc gccaaaaaaa tgactgaatt tggagaagta
     1261 ctcaagtggc tcaagaggat cccctgctaa gggattaggc tgggtaaccg gtgcgagggt
     1321 tcgaatccct ccttctccgc cattcaaaaa cgaggtgtag cgcagtttgg tagcgcacat
     1381 ggtttgggac catggggccg ggggttcgag tcccttcacc tcgaccaact taagctttta
     1441 gttcagttgg ttagagtgcc caactcatgg ctagtaattc tagggtttga gtccatgaag
     1501 gttattcttc ataggggtgt agctcagttg gtagagcgtc ggtctccaaa accgtgcgcc
     1561 gggggttcga gtccctccac ccctgccaaa taaaaaggac ttgaaaaaag ttggatttta
     1621 gagtagtata agatagtaaa taagatttcg aggtgtagcg cagtttggta gcgcacatgg
     1681 tttgggacca tggggccggg ggttcgagtc ccttcacctc gaccaagaaa agggcctata
     1741 gctcaggtgg ttagagcgca cgcctgataa gcgtgaggtc gctggttcga gtccagctag
     1801 gcccaccatt tgcccagata gctcagtcgg tagagcaggg gactgaaaat ccccgtgtcg
     1861 gtggttcgat tccgcctctg ggcaccagga atacggcggt atagcttagt tggctagagc
     1921 gttcggttca tacccgaaag gtcataggtt cgactcctat taccgctacc atctaactat
     1981 atc
//
LOCUS       DAMJWO010000186         1884 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.192, whole genome shotgun sequence.
ACCESSION   DAMJWO010000186 DAMJWO010000000
VERSION     DAMJWO010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1884
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.192"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            160..1740
                     /locus_tag="PC366_003702"
     CDS             160..1740
                     /locus_tag="PC366_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HDF2579163.1"
                     /translation="MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIDMY
                     NSYTVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGDENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYDTSTLIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     NKLLNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTVN
                     ATDLISNISLTMKELLDI"
BASE COUNT          734 a          168 c          370 g          612 t
ORIGIN      
        1 taaataattg ttttaattca aaattttttg ttattttaaa ttatttcaaa actcttagtt
       61 ttagtgattt tatttatgat atttatggga ttaaaagatt tcaatagata tttttggtaa
      121 gtatttaaga agtctttaac tttataggag tgataattta tgctaatagg tacatctaaa
      181 ttaagcagaa atgttgatac tgcatgtgta gaagaagtag ggattccaat gattgtattg
      241 atggaaaatg cggttatatc tgcaatgaaa aatatggata tagacatgta taatagttat
      301 acagttgtat gtggtgttgg aaataatgga ggagatggtc ttggaatagc aagacatcta
      361 aatacatatg gaaaagaagt aaacgtattt ttagtaggta atcttgaaaa actaagtgaa
      421 tgctctaaaa taaattacaa tgtactttta aatatgggaa ttaatattat aaatattaat
      481 aaaaatgatt taagtgaaaa aaattatgga gatgaaaatg aagtagataa aattattaaa
      541 gttgagaaac aaaatattat aaaaaataaa aatttaacaa tttttaaaga tagagtatct
      601 aaaagtgatg ttgtagtaga tgctatattt gggactggat taaaacgtga tataactggt
      661 atttttaaag aagttattga catagtaaac gataatagca aaaatacata ttctatagat
      721 attccttcag gtatagatag cgataatgga aatgtattag gaacttgtat tagagcaaac
      781 aaaacgatta gctttgagtt ttataaaaga ggttttctaa actatgacac tagcacactt
      841 ataggtgatg tagttgtaga aaagataggt gttccagatt ttattacaag aaaataccat
      901 gatgaagagt tcataactga taagactttt gtaaaaaata atattagaag aagagataag
      961 catggtttta aaagtgattt tggaaaagta tctatagttg caggttcaaa aggattttat
     1021 ggtgcaagtt tcatagcaac tgaatctgct gttaagagtg ggagtggact tgtaacatta
     1081 attagtagtg aagatgtgca agaaaaggta tctattagac ttacagaagc aatgacttta
     1141 aattttgaag aagaaagatt aaataaatta cttaattcta gtgatgcaat tggttttggt
     1201 ccaggtatgg gagataatag tcaaacattt gataaattac ttaagatagt agaaaattct
     1261 aattgcccaa tagtattaga tgcagatgga ttgaacgtta tgaaggacag atgttataag
     1321 tttttagaat ggaaaaatag atttgtaatt acacctcatt tgggagaaat ggccaggttg
     1381 acaggagatt caattgggta tataagagaa catagagtag atgttgcaaa agaatttgct
     1441 caaaaatata atctggtggt gcttttaaaa ggttatcaaa ctgtcataac agatggtaaa
     1501 aaaacatata taaatcctac aggaaatagc tgtatggcaa ctggtggaat gggtgattgt
     1561 ttgcttggaa tgattacttc atttataggt caaggtatgg atatattgga agctacagtt
     1621 agtggagcat atatacatgg ctatatagga gataaattga gcaaagcaat gtatacggta
     1681 aatgctacgg atttaataag taacatttca ttaacaatga aagagttgtt ggatatataa
     1741 ttgattaaaa aatagctacg cacacttgtg actttagtca tgagttagta gctaaaatag
     1801 tcagcatata gggaaaccta tatgtagaga taggatagaa cctatccaat actacttgaa
     1861 ttgctaaaat cccctaaagc taac
//
LOCUS       DAMJWO010000187         1777 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.193, whole genome shotgun sequence.
ACCESSION   DAMJWO010000187 DAMJWO010000000
VERSION     DAMJWO010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1777
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.193"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            132..1181
                     /locus_tag="PC366_003703"
     CDS             132..1181
                     /locus_tag="PC366_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDF2579164.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKDESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKAGNVNVRTDVQFGVMAGAFAGGEGDFTTAFEPTATAMEKEGS
                     GYIVTSIGKDSGEIPFTAYSTTRSYMKNNKDLIQRFTNAVYKGQLWVQQASSKEVAKA
                     MQPFFEDISLEDLTTVVDRYKSIDAWSQNPVLKEEGLKKLMTVMKEAKELDKEAPYKD
                     IVNTEFANNAIKNIK"
     gene            complement(1331..1678)
                     /locus_tag="PC366_003704"
     CDS             complement(1331..1678)
                     /locus_tag="PC366_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDF2579165.1"
                     /translation="MHENKKNLLDGSLAQYNDTAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
BASE COUNT          654 a          243 c          282 g          598 t
ORIGIN      
        1 actaaacata aaactgaaaa ttattattaa gtttttgtag aaatattata agcatagata
       61 catttttgta acaactacaa taaattttta atactatata ctattcgtat gtcttatggg
      121 aggtatttat tatgtttaaa aaaatagtcg caatagcaag ctctatcatt gtaagtacaa
      181 tatgtctaac tggatgtgat tttaactcta atgacaaaaa agatgaatct tcttcgtcta
      241 aaaatctgga taaagtaact atagcagaag ttactcactc tgttttttat gctccacagt
      301 atgctgctat tacgaaagga ttctttgaag atgaaggtat aaagattgac cttataaata
      361 cccaaggtgc agataaaact atggcagctt tgatttcagg tgaagcaaac gtaggtttaa
      421 tgggtcctga agcatctata tatgtatata atcaaaacaa aaacgattat gcagtgaact
      481 ttgctcaatt gacaaaaaga gatggtagtt ttctagttgc taggaaaaaa atgcctaatt
      541 tctcttacaa tgatttaaaa ggaacagaaa tattaggtgg tagaaaaggt ggagttccac
      601 taatgacttt tgaatatgtt ctaaaagaaa aaggtcttac tattggagaa aatctaaaag
      661 caggcaatgt taatgtaaga actgatgtac aatttggtgt aatggctgga gcttttgcag
      721 gtggagaggg tgactttaca acagcatttg aacctacagc aacagcaatg gaaaaagaag
      781 gtagtggata tatagttaca tctataggaa aagattctgg agaaatacct tttacagcat
      841 actctactac gagatcatac atgaaaaaca ataaagattt aattcaaaga tttacaaatg
      901 ctgtttataa aggtcaatta tgggttcaac aagcatctag caaagaagta gctaaggcta
      961 tgcaaccttt ctttgaagat atatctttag aagatttaac aacagttgta gatagatata
     1021 aatcaataga tgcatggtct caaaatcctg tattaaagga ggaaggtttg aagaaattga
     1081 tgactgttat gaaagaagct aaagaactag ataaggaagc accttataaa gatatcgtaa
     1141 atactgagtt tgcaaacaat gctataaaaa atattaaata aaatatatta gttttagcta
     1201 gatattttct tgtttttata atgaaaatta acaaaaatat aaaaagagcc ttttaaaaga
     1261 ctctttttat atttgagatt aaagtttata taataaaata gatattaaag tactaactgt
     1321 acttatatat ctatcctctg tattctgctc cagcattaat ttttgtaatt tgaacggcta
     1381 ccatttcttc attgcttcca ttagtaattt catgccactc tcctgttggt acaaatacag
     1441 tatcgccgtt ttttacatca cattcatgct caccaagttt cattttacct tctcctttta
     1501 ggaacacaaa tatttgttca ccattagggt gtctatgagc attaagaact tgattaggtt
     1561 taaaataata aacttctgaa gttatatcgt taccagcaaa tactggtatt tttggaactg
     1621 ctgtatcatt atattgagct aagcttccgt ctaatagatt ctttttattt tcatgcatac
     1681 tagaaatacc tcttttctat attatagatt tactattatt ataccaatat aagaaaatag
     1741 tattctcact ttacacaata ggaataaaat tctttta
//
LOCUS       DAMJWO010000188         1770 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.194, whole genome shotgun sequence.
ACCESSION   DAMJWO010000188 DAMJWO010000000
VERSION     DAMJWO010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1770
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.194"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(97..1017)
                     /locus_tag="PC366_003705"
                     /pseudo
     CDS             complement(97..1017)
                     /locus_tag="PC366_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428810.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
     gene            complement(1306..>1770)
                     /locus_tag="PC366_003706"
     CDS             complement(1306..>1770)
                     /locus_tag="PC366_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2579166.1"
                     /translation="ELSRKTIGSLNRNKARLKVARLQEHIANQRKDFLQKLSTKLIKE
                     NDIICIEDLQVKNMIKNHKLSRSISDVSWSEFIRQLEYKANWYGRKIVKVGKFFASSQ
                     ICNKCGYKNEEVKDLSIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
BASE COUNT          562 a          265 c          214 g          729 t
ORIGIN      
        1 atattaacaa ataataaaaa aattaatttg attgtatata aattagtttg ttattaaatt
       61 agtattaaaa agttcaaaaa tttacttaga aagaatctat aattcgattt ctatgtttgt
      121 tgagaatgca attacagctt ttccaattat ttttacttca actggcttat tatctgaaat
      181 aattactttt actaacatct tgcctttgcg ttttattgct tctccttgaa ctgcttcaaa
      241 tataaactct gtgttgggta taggtattac tttataatgt acaaggtacg cacctaaagg
      301 tccattagca tttcctgtaa cagggtcttc tgaaatacca attgcaggag caaacattct
      361 tccatgaact tgtagagttt ctttattatg taatgtaaaa atataatatc cattacattt
      421 tatttcttga cttattttcg ataattcata taaatttgga gataaactat ttaatgttga
      481 taattccttt attccaatca taacttttga atgtcctgta gatgatatgg caataggaca
      541 atctgtacga atatcttcat ttaaaatacc aaatgcatta agtaatcttt tttgataggt
      601 ttgttgtaat ggtggagata cttcaatttt tccttgtgtc ataattattt cataatcatt
      661 atcttttttt ataatatcaa ctggtaatat tccagcacca gttttttgaa atactgtttt
      721 gttattgaat tggttttcta ctgctctaac ataatgggca gcaatagtag catgaccaca
      781 tataggaact tcattagttg gtgtaaaaaa tctgatatgt acatcataat tttcttgatg
      841 atttttagcc aatttattga aaataaaagc agtttatgaa ttatttaatt ctcttgttat
      901 tttttgcatt tgtgattcag ataagccatc agcatttgta attacaccag ctggattacc
      961 tgtgaatctt tcttttgtaa atgagtcaac ttgataaaga cgaaattttt tattcatatt
     1021 atataatcct ttctaaacat tagattagtt tatctacata gaaaacttga gataaattat
     1081 tatttattat tatctgttta aataaaatta ataaaataac atatgtctat attaaaattt
     1141 aaaaatatac atctaaaaaa gtagtattat gtaaggctct atgctacact gaacctccca
     1201 tgactaaagt cacagggttc ctgcttcata gaattttgca tactaaaata tgtcttacta
     1261 attctccaca ggctatcccc gtagttccta cggttcttac atacgttatt tattttgaat
     1321 tgttattagt cttaatcctt cttttaatat atttatactt gcatttatat ctctatcgtg
     1381 agtttcatta caactaggac aaatccattc tcttatactt aagtccttca cttcctcgtt
     1441 tttataccca catttattgc atatttgtga acttgcaaag aatttaccta cctttacaat
     1501 ttttctacca taccaattag ccttgtactc taattgacga ataaattctg accatgatac
     1561 atctgaaatt gagcgagata gtttatgatt tttaatcata ttctttactt gtaaatcttc
     1621 tatgcaaata atatcattct cttttattaa tttagtagat agtttttgta gaaaatcctt
     1681 tctttgatta gctatatgtt cttgaagtct tgcaactttt aatcttgctt tgtttctatt
     1741 taaactaccg attgtttttc tcgataattc
//
LOCUS       DAMJWO010000189         1740 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.195, whole genome shotgun sequence.
ACCESSION   DAMJWO010000189 DAMJWO010000000
VERSION     DAMJWO010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1740
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.195"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            300..767
                     /locus_tag="PC366_003707"
     CDS             300..767
                     /locus_tag="PC366_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDF2579167.1"
                     /translation="MKFLNVLIVVEDIEKSKKFYYDILGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKSDSEVKFNGNDAELYFEEDNFDTFVERLSTMKGIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEIGETMSSVCRRFLDSGLSIDEVAKRMDVTVEYIESVLE"
BASE COUNT          713 a          106 c          248 g          673 t
ORIGIN      
        1 tattagtgta tattaatatt cccttgaaat taaaaaaaca tagatatttc agtaatctaa
       61 aatagtctac aaaaataaca gttttagcaa aattaataag aatacatata gatttaaacc
      121 taaaagtatg aacatgtctg ttttttacaa gattaaaatt tatattatat gataaaatta
      181 acttaactat ttcaataaga cttataattt ttttctttat actagacctt attgaaacct
      241 ttatagttta attctaatta tatattataa ataaagtatg tgtatattaa ggaggtaata
      301 tgaagttttt aaatgtttta atagtagttg aagatattga gaaatcaaaa aagttttatt
      361 atgatatttt ggggttaaag gtaatctgtg attttggaga aaatgttgta ttagaaggta
      421 atatatcatt acaagaaaaa aagctttggt tagaatttat taataagagt gacagtgaag
      481 ttaagttcaa tggaaatgat gctgagttat attttgagga agataatttt gatacttttg
      541 ttgaaagatt gagtacaatg aaaggtatag attatgttca tctagctata gagcataggt
      601 ggggtcaaag agcaattaga ttttatgatt tagatgggca tattattgag attggagaaa
      661 ctatgtcatc tgtgtgtaga cgttttttag atagtggtct ttcaatagat gaggtagcta
      721 aaagaatgga tgtaactgtc gaatatattg aatcagtttt agaatagatg gattatatta
      781 aagtaaaact atattttgta tagaagtaag ggctgtaagt aaacttgtat ggaaacaaat
      841 ttacttacag tttttgtttt tgtaagatac agaatataat atttgttata attttatttg
      901 gatttttaaa aagtgcatga ttttccttac atattataat agaatttaat atttattgga
      961 tgatttaaat ttagaaaaat ataagtatta gcttataaaa gataattata cttactatca
     1021 agctgtagaa tcatatatac tattttatgt aattatgtta aaatttaatt gaacaaatta
     1081 aaaatatagt gaaaattgta gttttagttt atttatttaa taaatatttc aaataaaata
     1141 atgtttaaat aagaaacata aataataata ttattattgt tcttaaagac aaaaaatctt
     1201 agcttaaaaa tttgtatcat ataaaatccc tacatattat ggaagtaatg atacattata
     1261 tgatatacac aataaagtat aaaagtattt acatgttttt tctatatatt ttataagttt
     1321 taggtatgga aaattactaa ataaaaatta gattaatgat tatgatagta tagataaagt
     1381 ttattctttt tattaataga aattgttgta taaaaataat aaaagtgagg agagtgatat
     1441 ttaaataaaa aaattttaat aagtattggt aatatagttt ttagggatga ttattttatg
     1501 taaaaagttg ttatttgtaa agataaatat agaaaatatt ataagtattg atttagtgat
     1561 aatctaaaag gtgagaattg taataaaaag agaacatatc cttcaaatgg atgtaaactt
     1621 ataaataaca ttattacaag agatttatta tacatatact gcaactatta attagaattt
     1681 atactgtatt tgtatttaaa taaaaacaca aataatatta ttgtaaaaat ttataattat
//
LOCUS       DAMJWO010000190         1662 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.196, whole genome shotgun sequence.
ACCESSION   DAMJWO010000190 DAMJWO010000000
VERSION     DAMJWO010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1662
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.196"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..>1662
                     /locus_tag="PC366_003708"
     rRNA            <1..>1662
                     /locus_tag="PC366_003708"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          477 a          347 c          492 g          346 t
ORIGIN      
        1 gggacacgtg aaaccctgtg ggaagcagga gggaccaccc tccaaggcta aatactacct
       61 agtgaccgat agcgtatagt accgtgaggg aaaggtgaaa agaaccccgg gaggggagtg
      121 aaatagaacc tgaaaccctg cacttacaag ctgtggaagc acatttcttg tgtgaccgcg
      181 tactttttgt agaacgggcc aacgagttac gttaagtagc aaggttaagc acttaaggtg
      241 cggagccgta gcgaaagcga gttttaactg agcgttcagt tacttgacgt agacccgaaa
      301 ccgggcgacc tacccatgag caggatgaag cgaaagtaaa atttcgtgga ggtccgaacc
      361 cacgagcgtt gaaaagctcg gggatgactt gtgggtagcg gtgaaattcc aatcgagccc
      421 ggagatagct ggttctcccc gaaatagctt tagggctagc ctcaaggtga gagatacgga
      481 ggtagagcac tgaatgtcct agggggtatt gcacctaccg aagactatca aactccgaat
      541 gccgtcatct tatacttggg agtcagactg tgggtgataa gattcatagt cgaaagggca
      601 acagcccaga tcgtcagcta aggtccctaa atgtaagtta agtggtaaag gatgtgggat
      661 tgcacagaca accaggatgt tggcttagaa gcagccactc attcaaagag tgcgtaatag
      721 ctcactggtc gagtgatcct gcgccgaaga tttccggggc taaaacttac taccgaagct
      781 acggcatcag taatgatggg taggggagct tcccatacgg gttgaagcat gaccgtaagg
      841 acatgtggac agtatgggag tgagaatgtt ggcatgagta gcgagatgtg ggtgagaatc
      901 ccacaggccg taaacccaag gtttccaggg gaaggttcgt ccgccctggg ttagtcggga
      961 cctaagctga ggccgaaagg cgtaggtgat ggacaacagg ttgatattcc tgtactaccg
     1021 ataaccgttt gagagaaggg atgacacagt aggataagct aagcacactg ttggttatgt
     1081 gtgcccaagc attgaggcag tcaaagtagg caaatccgct ttgataatgc tgggatgtga
     1141 tggggagcga aatttagtag cgaagtagct gatttcacac tgtcaagaaa agtctctatc
     1201 gaggttaaag gtacccgtac cgcaaaccga cacaggtggg tgaggagagt atcctaaggc
     1261 cagcgagaga actgttgtta aggaactcgg caaaatgacc ccgtaactta gggataaggg
     1321 gtgccaccat caggtggccg cagagaatag gcccaagcga ctgtttacca aaaacatagg
     1381 tttctgctaa gtcgcaagac gatgtatagg agctgacgcc tgcccggtgc tggaaggtta
     1441 aggggatctg ttagagcaat cgaagcagtg aacttaagcc ccagtaaacg gcggccgtaa
     1501 ctataacggt cctaaggtag cgaaattcct tgtcgggtaa gttccgaccc gcacgaaagg
     1561 cgtaacgatt tgggcactgt ctcaacaaca gactcggtga aattgtaatt ccggtgaaga
     1621 tgccggatac ctgcgacagg acggaaagac cccatggagc tt
//
LOCUS       DAMJWO010000191         1600 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.197, whole genome shotgun sequence.
ACCESSION   DAMJWO010000191 DAMJWO010000000
VERSION     DAMJWO010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1600
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.197"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            115..1551
                     /locus_tag="PC366_003709"
     CDS             115..1551
                     /locus_tag="PC366_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HDF2579168.1"
                     /translation="MKFYKRILTLTLSISFVFANIQLVDAISSVEKIQGKNKYEIAGK
                     IADKNAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSARLKNVSKV
                     YIIGGTYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSIKKVNTVMLTNAY
                     KGEADAISIASVAARDKAPIILTNGQSIPFSTSGLKSYVIGGTASMSTTLVNNTKSTR
                     LGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHGPIVLVNDGSNKSI
                     LKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGVVKNVKPTTKTIKDGMYKVGKDIS
                     AGEYLITSNSGSYASYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYIKIEDSTMT
                     LAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNDSLGNAEGIVTN
                     DTFSGRRYITVEEGQYLILNDCYLIENE"
BASE COUNT          656 a          164 c          272 g          508 t
ORIGIN      
        1 tttgtaatat gcttaatata atttgcaatt ttacataagt ttgttaagta cataactaat
       61 ttaagaatat gtatttatat attaaaaatt tattatgagg gggacaattt tattatgaaa
      121 ttctataaaa gaatattaac attgacttta agtatttctt ttgtatttgc aaatattcaa
      181 ttagtagatg caatatcatc tgtagaaaaa atacaaggaa aaaataagta tgaaatagca
      241 ggcaaaatag cagataaaaa tgcatataaa actgctatat taattaatac tagtaactct
      301 attgcagatg gattaagtgc aagtggacta gcaggagctt taaatgcccc tatactatta
      361 actgaaaaaa atactatacc aactgagaca tctgcaagat taaaaaatgt atcaaaagtt
      421 tatataattg gaggaacata ttctattagt acatctgtcg aaaattcatt aaaatctaag
      481 aaaatgaaag ttgtaagaat taagggaaat gacagaataa aaacaagtta taatgttgca
      541 aaagaaataa attcaataaa aaaagtcaat actgttatgc taaccaatgc atataaagga
      601 gaagcagatg ctataagtat tgcatctgta gcagcaagag ataaagcacc aataattctt
      661 actaatggac aaagtatacc tttttcaact agtggtttaa agtcttatgt aataggagga
      721 acagcttcaa tgagtaccac tttagtaaac aatactaaat ctactagact aggagggagt
      781 actcgttttg aaactaataa agcaataata aataagtttt ataaggatgc tagagagttt
      841 tatatagctg gagcttatga attaacaaat gcacttgtag gatcttcttt atcaaaacat
      901 ggtccaatag ttttagttaa tgatggtagc aataaaagca ttttaaaaaa tgctaagaag
      961 ataacttcta taggatatat agattcaaat atagtacaac agtgtttaaa tataacaaat
     1021 ggaattggag atattaatac tggggttgta aaaaatgtta aacctactac aaagactata
     1081 aaagatggaa tgtataaggt tggaaaagat atatcagcag gtgaatactt aattacttca
     1141 aactcaggaa gttatgcttc ttattatgaa gttacaagtg atagtacagg taatgctgat
     1201 agtatacttt caaatgatat ttttagtggg actagatata tcaccttaaa gaatggtcaa
     1261 tatattaaaa ttgaggattc aacaatgaca ttagcaaagt atgctaaagc ccagaaggcc
     1321 aagaatggta agtttggaaa tggtatgtat aaaattggat tagaaattcc tgctggagaa
     1381 tatattataa tgtcaaattc ttctgatgca tattatgaag ttagaaatga tagcttaggt
     1441 aatgcagagg gaatagttac taatgatact ttttcaggaa gaagatatat aacggttgag
     1501 gaaggtcaat atttaatatt aaatgattgt tatttaattg aaaatgaata gatgtaattg
     1561 tatttaatag taaatcatat attttattta aggaaagatg
//
LOCUS       DAMJWO010000192         1336 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.198, whole genome shotgun sequence.
ACCESSION   DAMJWO010000192 DAMJWO010000000
VERSION     DAMJWO010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1336
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.198"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            27..101
                     /locus_tag="PC366_003710"
     tRNA            27..101
                     /locus_tag="PC366_003710"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="PC366_003711"
     tRNA            116..200
                     /locus_tag="PC366_003711"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            209..292
                     /locus_tag="PC366_003712"
     tRNA            209..292
                     /locus_tag="PC366_003712"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:243..245,aa:Leu,seq:tag)
     gene            322..398
                     /locus_tag="PC366_003713"
     tRNA            322..398
                     /locus_tag="PC366_003713"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Arg,seq:tct)
     gene            406..481
                     /locus_tag="PC366_003714"
     tRNA            406..481
                     /locus_tag="PC366_003714"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:439..441,aa:Gln,seq:ttg)
     gene            570..658
                     /locus_tag="PC366_003715"
     tRNA            570..658
                     /locus_tag="PC366_003715"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:604..606,aa:Ser,seq:tga)
     gene            662..737
                     /locus_tag="PC366_003716"
     tRNA            662..737
                     /locus_tag="PC366_003716"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:695..697,aa:Phe,seq:gaa)
     gene            744..817
                     /locus_tag="PC366_003717"
     tRNA            744..817
                     /locus_tag="PC366_003717"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:778..780,aa:Met,seq:cat)
     gene            832..908
                     /locus_tag="PC366_003718"
     tRNA            832..908
                     /locus_tag="PC366_003718"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:866..868,aa:Ile,seq:cat)
     gene            932..1008
                     /locus_tag="PC366_003719"
     tRNA            932..1008
                     /locus_tag="PC366_003719"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:966..968,aa:Pro,seq:tgg)
     gene            1016..1092
                     /locus_tag="PC366_003720"
     tRNA            1016..1092
                     /locus_tag="PC366_003720"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1050..1052,aa:His,seq:gtg)
     gene            1101..1176
                     /locus_tag="PC366_003721"
     tRNA            1101..1176
                     /locus_tag="PC366_003721"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1134..1136,aa:Lys,seq:ttt)
     gene            1184..1257
                     /locus_tag="PC366_003722"
     tRNA            1184..1257
                     /locus_tag="PC366_003722"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1216..1218,aa:Cys,seq:gca)
     gene            1264..1335
                     /locus_tag="PC366_003723"
     tRNA            1264..1335
                     /locus_tag="PC366_003723"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1296..1298,aa:Asn,seq:gtt)
BASE COUNT          320 a          310 c          355 g          351 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atgtaaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaatgcgc ggatgtggcg gaattggcag acgcactaga
      241 cttaggatct agcgccattg gcgtgggggt tcgactccct tcatccgcac catttttgtt
      301 tgatatacat atataaattg tgggtgcata gctcagctgg atagagcaac gcccttctaa
      361 ggcgtgtgtc cggggttcga atccctgtgc gctcaccaca tatattgggg attagccaag
      421 tcggtaaggc acatgacttt gactcatgta tgcgtaggtt cgagtcctgc atccccagcc
      481 aaatgatgta ttactaagct atatttgaac tatttttatt ttaaatatag ttaggttcaa
      541 ttttagaata agtttaagta tccgaatgtg gagaggtgtc cgagtggttt aaggagctgg
      601 tcttgaaaac cagtgacttc gaaaggggcc gtgggttcga atcccaccct ctccgccaaa
      661 tgcccagata gctcagtcgg tagagcaggg gactgaaaat ccccgtgtcg gtggttcgat
      721 tccgcctctg ggcaccaaaa tatggcggta tagcttagtt ggctagagcg ttcggttcat
      781 acccgaaagg tcataggttc gactcctatt accgctacta aaatttaatg tgggccatta
      841 gctcagttgg ttagagcgcc cggctcataa ccggtaggtc tggggttcga gtccctgatg
      901 gcccaccaca ttaaattaat taatataaat tcgaggtgta gcgcagtttg gtagcgcaca
      961 tggtttggga ccatggggcc gggggttcga gtcccttcac ctcgaccaat ataaggtggg
     1021 tatagctcag ttggttagag cgccagattg tggctctgga ggtcgtgagt tcgactctca
     1081 ttatccaccc caattcatat ggtctattag ctcagtcggt agagcacctg acttttaatc
     1141 agggtgtccc gcgttcgagt cgcggataga tcaccaaaaa ggtggcgaca tagccaagtg
     1201 gtaaggcagt ggactgcaac tccttgatcc ccagttcgaa tctgggtgtc gcctccaaaa
     1261 tattccaagg tagctcaacg gtggagcaac cggctgttaa ccggtaggct gtgggttcga
     1321 gccccaccct tggagc
//
LOCUS       DAMJWO010000193         1210 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.199, whole genome shotgun sequence.
ACCESSION   DAMJWO010000193 DAMJWO010000000
VERSION     DAMJWO010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1210
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.199"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            391..903
                     /locus_tag="PC366_003724"
     CDS             391..903
                     /locus_tag="PC366_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579169.1"
                     /translation="MKVKKFKSGIVMALTVMAIGASLTNVSAMELNKSKEFETKYNEM
                     KRDFQEDYGKEDKFNITLDDEFTKEEVNGAKGIIKTTNKMNNEVVVLNYFDEMKSGIE
                     FELKAKAEKNAILRDEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
BASE COUNT          542 a           84 c          209 g          375 t
ORIGIN      
        1 ttatttttag aatattcagt aaaataattt tgatatactc tatatatttt gtatgttaaa
       61 agtaaataaa ttattgttaa agaatgtaaa gacttttaaa ttttttatca caggatttta
      121 agtaaataag aaggattgga gtaattaaaa atttttattt tgcaaaaata agtatttatt
      181 tatatggata aatttgattt taaatctatc aatatagata aaatcttatt atttaacttc
      241 aactattcct taaaaaagca acttttaagg aatagttgaa acaaaaagtt tggttacata
      301 atagtaattt tagttacaag aatgaaactg taaaacttag gattttcttt atataatttc
      361 attgagaaca tttaatttag gaggtaaggt atgaaagtaa aaaaatttaa aagtggtata
      421 gtaatggcat taacagtaat ggcaattgga gcatcattga caaatgtatc agctatggaa
      481 ttaaacaaga gtaaagagtt tgaaactaaa tacaatgaaa tgaagaggga ttttcaagag
      541 gattatggaa aagaagacaa atttaatata acattggatg atgaatttac aaaagaagaa
      601 gtaaatggag ctaaagggat tataaagaca actaataaaa tgaataatga ggttgtagta
      661 ttaaattatt ttgatgaaat gaaatctggg attgaatttg agttgaaggc aaaagcagaa
      721 aaaaatgcaa ttttgagaga tgaatttcaa caaggttatg gaaaggaaga taaattcaaa
      781 gttgtgttag atgatgaatt tacaaaagaa gaggtaaatg gagctaaggg cattataaag
      841 actacagata aagagacagg tgaggttatc gtatataatt actttgatga gcttgaaaaa
      901 taatgcttaa agattacttt gattgaatga aaaggtaatt gtgttgagaa tattaaatga
      961 ctgaataaaa acagttgtat caaaaacaaa caataataga atgtaagaat gattgtgtcg
     1021 aaaatattaa atgactgaat aaaaaatagt tgcgtcaaaa acaaacaata atagaatgta
     1081 agaatgattg tatcaagaat ataaaatgat tcaacaaaaa acgattgtgt taaaaacaaa
     1141 caacaataga atgtaagaat gattgtatca agaatataaa atgactgaat aaaaacgatt
     1201 gcgtcaaaaa
//
LOCUS       DAMJWO010000194         1204 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.200, whole genome shotgun sequence.
ACCESSION   DAMJWO010000194 DAMJWO010000000
VERSION     DAMJWO010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1204
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.200"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            69..1109
                     /locus_tag="PC366_003725"
     CDS             69..1109
                     /locus_tag="PC366_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HDF2579170.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLEIKKDFENLGLDTI
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAIVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVITRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFEATESGFIKSRYIDNKSAVAMVLEICRYFKENNLTPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VDVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
BASE COUNT          466 a          144 c          197 g          397 t
ORIGIN      
        1 tttagttttc agaacatttg tatttatgtt ataatttgta taaatatatt tatttaggag
       61 gaaacaatat gaatttaaat ttaactaata ctataaattt aatgaaaaaa tatttggaca
      121 ttccaagccc agctggatat actgaaaatg cagttttaga aatcaaaaaa gattttgaaa
      181 atttaggtct tgacactatt cttacaaaaa aaggtgcact tatagctact cttcctggtg
      241 aagatgattc aaatcaaata acaatatctg cacatatgga tacacttgga gctatagtaa
      301 aagaaatatc atctgatggt actcttaaat accataaagt tggtggtgga tgttgggcag
      361 ctatagaggg agaaaactgc actgttataa ctagaaaagg taaaaaaatc agaggaagtg
      421 ttgtatttaa gtatgcttct actcatatat atggtcaaac aaaagctgcc actgaaagaa
      481 atgaagaaac aatgattatt agacttgatg aaaaagtatt tacaaagcaa gatgtattag
      541 atttaggaat aagtgttggg gattttgtat gcctagacca tagatttgag gctacagaat
      601 ctggttttat aaaatctaga tatatagata ataaatcagc tgtagcaatg gttcttgaaa
      661 tatgtagata ttttaaagaa aacaatttaa cgcctaagca tactactaac ttttatataa
      721 gtaattatga agaaattgga catggtgttt ctaaatgttt acctgaaaaa acaaaagaat
      781 ttgtagcaat agatatagca cctactggac caagtcaaac atctagtgaa catggtgtaa
      841 ctatagttgc aaaagataat ttatcattat atgattttaa tttaagaaac aagcttgtcg
      901 atgttgcaga agacaataat ttagactacg ctgtcgatgt atttactttc tatggttcag
      961 atgcttcaga agctattcgt tggggagaag atgttcaaat agcatgtgtt ggtcctggaa
     1021 caaacaatag tcaccattat gaaagaacac atatagaagc tattgaaaat acactaaaat
     1081 tacttataaa ttatatgctt aaagaataat taattatata ttttaccaaa gtcaattctt
     1141 aacaaataat taactttaat ttttattttt atacaaaaat tggtttttct atagacttaa
     1201 tttc
//
LOCUS       DAMJWO010000195         1165 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.201, whole genome shotgun sequence.
ACCESSION   DAMJWO010000195 DAMJWO010000000
VERSION     DAMJWO010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1165)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1165)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1165
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.201"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(282..773)
                     /locus_tag="PC366_003726"
     CDS             complement(282..773)
                     /locus_tag="PC366_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HDF2579171.1"
                     /translation="MGMIGCYTKISEENVFKLQQAEENLQDFVFEDANENSTINIDKA
                     WHAIHFTLTGCPFGGDDENIFSKLVLSGNILMEIDGEFPVMLITANDVKKLSKAMNSL
                     EEQAFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKKFIQEASDDGLAVIF
                     FIM"
BASE COUNT          449 a          168 c          107 g          441 t
ORIGIN      
        1 gtgataagta tccaaaagaa ttactggata taataagata gggtatttag ccttttaaga
       61 taaataaaaa tatctgcaac tatatattgc aaaaatttaa aactaattta tatatgctaa
      121 tataaatatt tataaagaca taagacaaat ttacctacag atttaaattt aacttatata
      181 ttttaaaagg ctaatataat atgtattttc ttctatacaa tcaaaaggct tcatatctaa
      241 gatatgttat gacactaata ttcacaattt tttagtaatt atcacattat aaaaaatatt
      301 acagctagtc catcatcaga tgcttcttgt ataaactttt taagctcaat tagatttgcc
      361 catacatatt caaaaaaatc atcttcactc tcatcattca taacaggata aatattattt
      421 tctaacatct cattaatatt aaatcttttt ctaaatgctt gttcttccaa actgttcatt
      481 gcttttgata gtttttttac atcatttgct gtaatcaaca tgacaggaaa ttctccatca
      541 atttccataa gtatgtttcc acttagtact aatttgctaa atatattctc atcatctcca
      601 ccaaaaggac aacctgtcaa agtaaagtga atggcatgcc atgctttatc aatattgata
      661 gtactatttt cgttggcatc ttcaaaaaca aaatcttgta aattttcttc tgcttgctgt
      721 aatttaaaaa cattctcttc acttatttta gtataacatc ctatcatccc cataattaca
      781 ttcctcctaa gtagcgtttt tttaattgta acttataatt aaacttagtt acaataaaat
      841 atattgagaa aagtattatt tcatcttaaa tttaaatacc tatattatca actaaaattc
      901 tgtgtttata gcgtaagtat tattattttt tcctaaaaat taaatgaatc agaagttcta
      961 taggcaatat tgactataaa taagaactat tacttttaaa aaaaatttaa gaaattatac
     1021 tgtagaatca tgctctactt attagcttca aataaaaaat aaatcatgtt ctcaaattaa
     1081 ataataaata acaataaatt taaattttaa actataagag tttctgaagt gttaataagc
     1141 ataccaataa ttatatgtgt aagaa
//
LOCUS       DAMJWO010000196         1146 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.202, whole genome shotgun sequence.
ACCESSION   DAMJWO010000196 DAMJWO010000000
VERSION     DAMJWO010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1146
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.202"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..>1146
                     /locus_tag="PC366_003727"
     rRNA            <1..>1146
                     /locus_tag="PC366_003727"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          293 a          253 c          352 g          248 t
ORIGIN      
        1 caggatggac ccgcgtctga ttagctagtt ggtaaggtaa cggcttacca aggcgacgat
       61 cagtagccga cctgagaggg tgatcggcca cattggaact gagacacggt ccaaactcct
      121 acgggaggca gcagtgggga atattgcaca atgggcgaaa gcctgatgca gcaacgccgc
      181 gtgagtgatg aaggccttcg ggtcgtaaaa ctctgtcctc aaggaagata atgacggtac
      241 ttgaggagga agccccggct aactacgtgc cagcagccgc ggtaatacgt agggggctag
      301 cgttatccgg atttactggg cgtaaagggt gcgtaggcgg tctttcaagt caggagtgaa
      361 aggctacggc tcaaccgtag taagctcttg aaactgggag acttgagtgc aggagaggag
      421 agtggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagttgcgaa
      481 ggcggctctc tggactgtaa ctgacgctga ggcacgaaag cgtggggagc aaacaggatt
      541 agataccctg gtagtccacg ctgtaaacga tgagtactag gtgtcggggg ttaccccctt
      601 cggtgccgca gctaacgcat taagtactcc gcctgggaag tacgctcgca agagtgaaac
      661 tcaaaggaat tgacggggac ccgcacaagt agcggagcat gtggtttaat tcgaagcaac
      721 gcgaagaacc ttacctaagc ttgacatccc aatgacatct ccttaatcgg agagttccct
      781 tcggggacat tggtgacagg tggtgcatgg ttgtcgtcag ctcgtgtcgt gagatgttgg
      841 gttaagtccc gcaacgagcg caacccttgt ctttagttgc catcattaag ttgggcactc
      901 tagagagact gccagggata acctggagga aggtggggat gacgtcaaat catcatgccc
      961 cttatgctta gggctacaca cgtgctacaa tgggtagtac agagggttgc caagccgtaa
     1021 ggtggagcta atcccttaaa gctactctca gttcggattg taggctgaaa ctcgcctaca
     1081 tgaagctgga gttactagta atcgcagatc agaatgctgc ggtgaatgcg ttcccgggtc
     1141 ttgtac
//
LOCUS       DAMJWO010000197         1049 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.203, whole genome shotgun sequence.
ACCESSION   DAMJWO010000197 DAMJWO010000000
VERSION     DAMJWO010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1049
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.203"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            115..867
                     /gene="cwlD"
                     /locus_tag="PC366_003728"
     CDS             115..867
                     /gene="cwlD"
                     /locus_tag="PC366_003728"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HDF2579172.1"
                     /translation="MEYYSVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNI
                     SEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGL
                     VILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYG
                     AQTFYPKDKQDSKELSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGF
                     LSNEKECKLLTDETYQEKIAWAIYIGIQKYLS"
BASE COUNT          467 a          108 c          161 g          313 t
ORIGIN      
        1 aaacatagtg aattaaatag gggcagaaat ataatatcat tacataataa tatattaata
       61 ccaataaata aagatatatc aatattaaaa aaatttaaat gtttgtacta atatatggaa
      121 tattatagtg tttttataag tatacatata cagggtgatg ttgtgagaaa gtacataaaa
      181 catataattt ttagttttgc aatgatatgt ctagtagtag tatccatatt tgaaattaaa
      241 aatatttctg aagatgttat caagtatatg ccagtaacaa acaaaactat aattttagat
      301 gctggtcatg gaggcattga tccaggtgca ttaaataagg ataagagtac atctgaaaag
      361 gatattaacc tagcaataac acttaagctt agagagctta tagaatcaag tggtggcctt
      421 gtaatattaa ctcgagaaga tgacagtagc ctttataaag aagaaaataa taaaactaca
      481 agacaaaaat ataatgagaa tttgaaaaat agaaaagaaa taatatctaa ttctaatgcc
      541 aatatgtttg tctctataca tcttaatgca tttgaacaat caaaatacta tggagctcaa
      601 actttttatc ctaaagacaa acaagacagt aaagaattat cgaagtgtat tcaagaagaa
      661 cttaaaagag tagtagataa gacaaacaac agagaagtca aaccaaggga tgatatatat
      721 cttttgaaag aaaataatat tccatcagta ctgatagaat gtggtttttt atcaaatgaa
      781 aaagagtgta aactcttaac tgatgaaaca tatcaagaaa aaatagcatg ggcaatctac
      841 ataggaatac aaaaatattt aagttgaaat aagtataaaa ataggtctaa atatgtaaat
      901 agcttgtatt aaagcagtta aaatgcatta atataggcta tttttatttt gacaaaaaaa
      961 tatttaaaat aaaagttaaa aagttgttga cttagaataa tatagatgat attatatatg
     1021 agtgcccaaa aggagcacca aaataagac
//
LOCUS       DAMJWO010000198          936 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.204, whole genome shotgun sequence.
ACCESSION   DAMJWO010000198 DAMJWO010000000
VERSION     DAMJWO010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..936
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.204"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..801
                     /locus_tag="PC366_003729"
     CDS             <1..801
                     /locus_tag="PC366_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
                     /protein_id="HDF2579173.1"
                     /translation="VPGDVLDYTIEVINAGPSTAQNVTLTDNIPASILSPEYSIDNGV
                     TFQPWNGSLSIGTLGAGEIRNIIIRGIVSQTAIGTIINTATVSSTTPDPNLNNNTSTS
                     EIDISSSADISVIKLANKTEACVEEQIDFVIVVSNAGPENAQNVTLIDNVSDKLKKAV
                     FSLDRGVSFQPWTGSLNIGTLPAGTLRVILLRGIIKSTCLDRLTNIAEVTSTTPDSNL
                     NNNISRVQVEIKQCCCNDCCCNNCSNCCCNDCGCKDCCCNCCKNDFWC"
BASE COUNT          368 a          123 c          156 g          289 t
ORIGIN      
        1 gtaccaggcg atgtactaga ctatacaatt gaggtgataa atgcaggacc gtctactgct
       61 cagaacgtaa ctttaacaga taatatacca gcttctattt taagtccaga atattcaata
      121 gataatggag tgacttttca accatggaat ggaagtctta gtataggcac tttaggtgct
      181 ggagagataa gaaatatcat aataagggga atagtaagtc aaacagcaat aggtacaatt
      241 ataaatacag caacagtaag ttcaactaca cctgacccaa atctaaataa caatacttca
      301 acatcagaaa tagatataag ttcatcagca gatatttctg taataaaatt agcaaataaa
      361 acagaagcat gtgtagaaga gcaaatagat tttgtaatag tagtatcaaa tgcaggacca
      421 gaaaatgctc aaaatgttac tttaatagac aatgtttcag ataagcttaa gaaagcagta
      481 ttttcacttg atagaggtgt aagtttccaa ccatggactg gaagtcttaa tataggtaca
      541 ctaccagctg gaactttaag agttattcta ttaagaggaa ttataaaatc aacatgtctt
      601 gatagattaa caaatattgc agaagttact tcaacaacac cagattcaaa ccttaacaat
      661 aatatatcaa gagtgcaagt agaaataaaa caatgttgtt gtaatgattg ctgttgtaac
      721 aactgtagta attgttgttg caatgattgt ggttgtaaag attgttgctg taattgttgt
      781 aaaaatgact tttggtgttg attttataaa ataattttgt ataccttaaa ttaaactgaa
      841 ataaaaaata aattcacata tgagtaaaat attttataaa tattaataaa ttttctatct
      901 ttgatatgga ccacattcgt aatactagtt attaaa
//
LOCUS       DAMJWO010000199          841 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.205, whole genome shotgun sequence.
ACCESSION   DAMJWO010000199 DAMJWO010000000
VERSION     DAMJWO010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..841
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.205"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(109..822)
                     /locus_tag="PC366_003730"
     CDS             complement(109..822)
                     /locus_tag="PC366_003730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2579174.1"
                     /translation="MINIIICEGKKSERVILNDYINTFFYNYNFEYNIKEFENGGDLL
                     KKYPNNVDIIFMDIDLNDENGFNVSKEIKKFDESVRIIFVSSSNKYIKKGYEIGVYRY
                     LEKPLKYSLFKEAISSYLKECYKNEAILSIKCKCKIYFIKVDDILYLEVLKNDLTIHT
                     EKGIYTFKNSMKEIESNLEEHNFFRCHKSYLINLMKVNMLDIENNIVFINQNSIIVSR
                     YKIKLLREKLNSCLVDVII"
BASE COUNT          297 a          113 c           61 g          370 t
ORIGIN      
        1 attgatgaaa ggtatatttt taactataat tagtttttat tataaatttt ttcatatttt
       61 acaatagata tattctatta gaatagaata taagggcaaa aatttacctc aaattattac
      121 atctaccaaa caactattta acttttctct caataatttt atcttataac gacttacaat
      181 tattgaattt tgatttataa atacaatatt attttctata tctagcatat ttaccttcat
      241 taaatttata aggtagcttt tatgacatct aaaaaaatta tgttcttcta gatttgattc
      301 tatttctttc atactattct taaaagtata tattcctttt tcagtatgta tagttaaatc
      361 attttttaaa acttctaaat ataaaatatc atctaccttt atgaaatata tcttgcattt
      421 acattttata gataaaatag cttcattttt gtagcattct tttaaatatg atgatattgc
      481 ttctttaaat agagagtatt ttaagggctt ctctaaatat ctataaactc ctatctcata
      541 acctttcttt atgtatttat ttgatgagga tacaaatata attcttacac tttcatcaaa
      601 ttttttgatt tcttttgaaa cattaaatcc attttcatca tttaagtcta tatccataaa
      661 tatgatatca acattattag gatacttttt taataaatcg cctccatttt caaactcttt
      721 gatattgtat tcaaaattgt aattataaaa aaaggtattt atataatcat ttagaattac
      781 cctctctgat tttttacctt cgcaaataat aatattaatc atattacacc ccttatataa
      841 t
//
LOCUS       DAMJWO010000200          752 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.206, whole genome shotgun sequence.
ACCESSION   DAMJWO010000200 DAMJWO010000000
VERSION     DAMJWO010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..752
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.206"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..>752
                     /gene="tuf"
                     /locus_tag="PC366_003731"
     CDS             <1..>752
                     /gene="tuf"
                     /locus_tag="PC366_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDF2579175.1"
                     /translation="ELLELVEMEVRDLLTEYDFPGDDTPIVRGSALMALEDPKSEWGD
                     KIVELFEQIDEYIPAPERDTDKPFLMPVEDVFSITGRGTVATGRVERGVLKVQDEVEL
                     VGLTEAPRKVVVTGVEMFRKLLDQAQAGDNIGALLRGVQRNEIERGQVLAKTGSVKAH
                     TKFTAEVYVLKKEEGGRHTPFFDGYRPQFYFRTTDVTGACKLPEGIEMVMPGDNVTME
                     VDLINSIVVEEGLRFSIREGGRTVASGVVATI"
BASE COUNT          310 a           94 c          187 g          161 t
ORIGIN      
        1 gagttattag agttagtaga gatggaagta agagatttat taacagaata tgatttccca
       61 ggagatgaca ctccaatagt aagaggttca gcattaatgg cattagaaga tccaaagagc
      121 gagtggggag ataagatagt agaattattc gagcaaatag atgagtatat accagctcca
      181 gagagagata cagataagcc attcttaatg ccagtagagg atgtattctc aatcacagga
      241 agaggaacag ttgcaacagg aagagtggaa agaggagtac taaaagtaca agacgaagta
      301 gaattagtag gattaacaga agcaccaaga aaagtagtag taacaggagt agagatgttc
      361 agaaaattat tagaccaagc acaagcaggg gataatatag gagcattatt aagaggagta
      421 caaagaaacg agatagaaag aggacaagta ctagcaaaga ctggatcagt aaaggcacac
      481 acaaagttta cagcagaagt atatgtactt aaaaaagaag agggtggaag acatacacca
      541 ttctttgatg gatatagacc acaattctat ttcagaacaa cagacgtaac aggagcttgt
      601 aagttaccag aaggaataga gatggtaatg cctggagata acgtaacaat ggaagtagac
      661 ttaataaact caatagttgt agaagaggga ttaagattct caataagaga aggtggaaga
      721 acagtagctt caggagttgt tgctacaata at
//
LOCUS       DAMJWO010000201          723 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.207, whole genome shotgun sequence.
ACCESSION   DAMJWO010000201 DAMJWO010000000
VERSION     DAMJWO010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..723
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.207"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..>723
                     /locus_tag="PC366_003732"
     CDS             <1..>723
                     /locus_tag="PC366_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003467946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HDF2579176.1"
                     /translation="KNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGD
                     STTMYPSQNISDEIKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRT
                     VPYISKVSGVPIVDLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEV
                     SLGPEMKSTGEVLGVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAK
                     DMKELGYTFVATEGTAKSLRENG"
BASE COUNT          292 a           75 c          154 g          202 t
ORIGIN      
        1 aaaaatccag tacttataga taaatatcta actggtagag aaatagaagt agatgctata
       61 tgtgataagg aagatatatt gatacctggt ataatggaac atttagaaag agctggagtt
      121 cactctggag atagtacaac aatgtatcca agtcaaaata tatctgatga aataaaagaa
      181 aagatagtag aatacactaa aaaaatagct ttagacctta atgtgcttgg tatggttaat
      241 atacaattta tagaatttca aaatgaatta tatataattg aggttaaccc tagagctagt
      301 agaacagttc catatataag taaagtaagt ggagtaccaa tagttgactt ggctactaag
      361 tgtatgttag gagctaaatt aaaggattta ggatatggta caggagttta caaagagcca
      421 aaattagtat cagtaaaagt accagtattc tcaatgtcta aattatctaa agttgaagta
      481 agtctaggac ctgaaatgaa gtctacagga gaagtcctag gtgtaggaga aaatttagaa
      541 gaagccttat ataaagggtt cttggcagca ggtagacata tgtctgatga aagaggagta
      601 gtacttgcta ctgtaaataa tcatgataaa gatgagttta tagagatagc aaaagatatg
      661 aaagaattag gatatacttt tgttgctaca gaaggaacag cgaagagttt aagagaaaat
      721 gga
//
LOCUS       DAMJWO010000202          700 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.208, whole genome shotgun sequence.
ACCESSION   DAMJWO010000202 DAMJWO010000000
VERSION     DAMJWO010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..700
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.208"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..423
                     /locus_tag="PC366_003733"
     CDS             <1..423
                     /locus_tag="PC366_003733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2579177.1"
                     /translation="TISKKYKMRSVNPLKAWVKEYNLHKEIKETPKGGLFMETRKTTL
                     DERVEIVKDCIEHDFNYNLIAKKYFVSYSQVRRWTLKYKENGIVGLEDRRGKAKKEDE
                     LTQLDEIKLELKIVKAEKHKLQLENAFLKKLKNIERGW"
     gene            495..>700
                     /locus_tag="PC366_003734"
     CDS             495..>700
                     /locus_tag="PC366_003734"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2579178.1"
                     /translation="MQLCEIAKVNRSGYYKWLNRDKSNLELENIKLATLITNIYEEKK
                     GVFCSLRMTLQLNREYKLNVNHKRV"
BASE COUNT          307 a           78 c          126 g          189 t
ORIGIN      
        1 actatctcaa aaaaatataa aatgaggtct gttaatccac taaaagcttg ggttaaggag
       61 tataatcttc ataaggagat aaaagaaacc ccgaagggag gactctttat ggagactaga
      121 aaaacaacat tagatgaaag ggttgaaatt gttaaagatt gtattgagca tgattttaat
      181 tacaatttaa tagcaaaaaa atactttgtt tcatacagcc aagttagaag atggactctt
      241 aaatataaag aaaatggtat agttggttta gaagaccgaa gaggtaaagc aaaaaaagaa
      301 gatgagttaa ctcaattaga tgaaataaag ttggaattga aaattgtaaa agcagaaaaa
      361 cacaaattac aactggagaa tgcattctta aaaaagttaa aaaacataga aagagggtgg
      421 taattacact atccaagaat gaaaataaat ataaagctat tcaatcctta ttcaatgaaa
      481 aaaaagcttc gcttatgcaa ttatgtgaaa tcgctaaagt aaatcgttct ggatactata
      541 aatggctcaa tcgagataaa agtaatttag aacttgaaaa cattaaatta gcaactttga
      601 taactaatat atatgaagaa aagaagggag ttttttgctc tttaaggatg accttgcagt
      661 taaacagaga gtataaactt aatgtcaatc acaagagagt
//
LOCUS       DAMJWO010000203          697 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.209, whole genome shotgun sequence.
ACCESSION   DAMJWO010000203 DAMJWO010000000
VERSION     DAMJWO010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..697
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.209"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            30..689
                     /locus_tag="PC366_003735"
     CDS             30..689
                     /locus_tag="PC366_003735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2579179.1"
                     /translation="MLDAFITIVSSIIEIWSCKKVFDYTSQSKTDLKKLNMYFLFSVF
                     LIISSLYINIGANSRILICIFVMFVFYKSNYKVNIYKCLVISFFYWLILIGINGLSML
                     LVATVSNLDNMNVLLSGSLYRYEAIFLGKIMLGILLYVYKASFKNFKISKKEIYICIP
                     MIANLLSFFVLYDYIINLVKISPERRTAFLVIVLLLILSNISIFVLIHIILKIKIRKI
                     R"
BASE COUNT          251 a           58 c           89 g          299 t
ORIGIN      
        1 ataatttaat catttttgag gatattatta tgttagatgc atttataaca attgtttctt
       61 ctattataga aatatggtca tgtaaaaaag tttttgatta tactagtcag tcaaagaccg
      121 acttaaaaaa actaaatatg tattttctct tttctgtttt tcttattatt tcttctttat
      181 atataaatat aggagctaat agtagaatct tgatatgtat atttgtaatg ttcgttttct
      241 ataagtctaa ctataaggtt aatatatata aatgtctggt aatctcattt ttttattggt
      301 taatattaat aggtataaat ggattaagta tgttattagt agcaacagta agcaatttgg
      361 ataatatgaa tgttttactt agtggcagtt tatatagata tgaagcaata ttcttgggaa
      421 agataatgtt aggtatatta ctttatgttt ataaggcttc ttttaaaaat tttaaaataa
      481 gtaaaaaaga gatatacata tgtattccta tgatagcaaa tttattgtca ttttttgtac
      541 tttatgatta tattattaat cttgtaaaaa tctctcctga aagaagaact gcttttttag
      601 taatagtttt actattaata ttatctaaca tttcaatctt tgtattaata catataatac
      661 ttaagattaa aattaggaaa ataagataaa ttttaat
//
LOCUS       DAMJWO010000204          659 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.210, whole genome shotgun sequence.
ACCESSION   DAMJWO010000204 DAMJWO010000000
VERSION     DAMJWO010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..659
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.210"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
BASE COUNT          238 a           71 c           76 g          274 t
ORIGIN      
        1 taaaacctat ttacactaat tatctaaata tctctttatt tttataatct tttatgactt
       61 atttatattt ttcattttta taaaaaaaca ataattaaga atataactat attctacatg
      121 taaaaatttt tttatttaaa ctcaattttc tgataacttg ataatttttc aaaatttata
      181 gttgactttt attttttact gtattaaact aattactata caaaacagaa aacaaaattt
      241 tcaaaattat taaattaaaa ggagaggtaa atatgaagac tttattaaac aaacaagtac
      301 gattttttag tagccaattt agttagggtt tgtacctaag ttaagacaaa ttgtcataac
      361 atagatacaa gccccttagg attatgattt ttaaggattg tatctatgtt ggctatagta
      421 attgttgtta aagtttttat tttatcatca taatatagag ccacatggat tatactgtgt
      481 ggcttattcg aatttttgcc atacagttat atatactgtg tggttttttt atatcaaaat
      541 cattttttaa aaccaaattt aaaaaaccat ttaaaatatt ttcaaagggg tgttttattt
      601 atgtcaggta ttatatctgt aatgacgcaa agtttaattt tatcgattat ggcactggg
//
LOCUS       DAMJWO010000205          624 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.211, whole genome shotgun sequence.
ACCESSION   DAMJWO010000205 DAMJWO010000000
VERSION     DAMJWO010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..624
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.211"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(118..597)
                     /locus_tag="PC366_003736"
     CDS             complement(118..597)
                     /locus_tag="PC366_003736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HDF2579180.1"
                     /translation="MPNKLIKNLLSGILQILFFLLGLVIVVGGFKSFMYLCFSGEATL
                     QGTISGILMFILGVSYFIIIKSLIEVLSSSEHSLFVKDNVKRFRIIGYLLLLNSIMEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVFVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
BASE COUNT          244 a          104 c           49 g          227 t
ORIGIN      
        1 taatctttta attttagcat tatagtttat gtattatacc ctaatatatt ttattttaaa
       61 ttactagtta atcactcttt tctggttatt tatctcctat atattaaagt gtcacaccta
      121 aatagttaaa tcattatcct cttttatctt tattgccttt acaaatccat ctgcaattac
      181 aaaactcata agagaagtta taaaatatac aaatactgga acagtaaaat aaaatccaaa
      241 tcctaaatct aggaatctca ttccttttcc agtagtacca aaagttgaaa taaactccat
      301 tatagagttt aaaagcaaaa gatatccaat aatcctaaat ctttttacat tatcttttac
      361 aaataagcta tgttcagaac tacttaatac ttctatcaat gattttataa tgataaaata
      421 tgatacacct aaaataaaca ttaatattcc agaaatagtg ccttgtagag ttgcttctcc
      481 actaaaacag aggtacataa aacttttaaa tcctcccaca acaattacta accctaaaag
      541 aaaaaataaa atttgtaata taccacttag taaatttttt ataagtttat taggcatcat
      601 accaactcct ttaaaatatt ttat
//
LOCUS       DAMJWO010000206          561 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.212, whole genome shotgun sequence.
ACCESSION   DAMJWO010000206 DAMJWO010000000
VERSION     DAMJWO010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..561
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.212"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..161
                     /locus_tag="PC366_003737"
     CDS             <1..161
                     /locus_tag="PC366_003737"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579181.1"
                     /translation="KTAFNEETRGRFKNISLENDNRKFKSVEEELKYLRMENEFLKKL
                     STLLDKSK"
     gene            215..>561
                     /locus_tag="PC366_003738"
     CDS             215..>561
                     /locus_tag="PC366_003738"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDF2579182.1"
                     /translation="MCKLIGVSRSGYYKWLSYSKKSSDRGIKDRIIKDYIIEIHKKYR
                     GTYGRKRICTYLNKILDSPINHKKVYRLMKELGIKSIIRKKVYRRKFKSYEVYDNILN
                     REFRANQPLEKIC"
BASE COUNT          243 a           46 c           98 g          174 t
ORIGIN      
        1 gtaaaactgc atttaatgag gaaactagag gcagatttaa aaatattagt ctagaaaatg
       61 ataatagaaa atttaaatct gttgaagaag aattgaagta cttacgcatg gagaatgaat
      121 ttttaaaaaa gttaagtacc ctattggaca agtcaaagta agcgataaat ttaaaacaat
      181 taaacttatg tctaggaagt atagtatttc tagtatgtgt aagttgatag gtgtgtcaag
      241 aagcggttac tataaatggc taagttattc taaaaaatct tccgataggg gtatcaaaga
      301 tagaattatt aaggattata taattgaaat acataaaaaa tatagaggaa cttacggtag
      361 aaaaagaatt tgtacttatt taaataaaat acttgatagc cctattaatc ataagaaagt
      421 atataggttg atgaaagaac taggaattaa atctattatt agaaagaaag tatatagacg
      481 taagtttaaa tcatatgagg tatatgataa tatattaaat cgtgaattta gagctaatca
      541 accattagaa aaaatttgta t
//
LOCUS       DAMJWO010000207          550 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.213, whole genome shotgun sequence.
ACCESSION   DAMJWO010000207 DAMJWO010000000
VERSION     DAMJWO010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..550
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.213"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            232..>550
                     /locus_tag="PC366_003739"
     CDS             232..>550
                     /locus_tag="PC366_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDF2579183.1"
                     /translation="MNLQSKWVNFLKPTYVSDEIKRKKLQVIIFFSITYGLSYSLGLL
                     AICFNHLIDSEILAQFMMILPLSSVSIAKFYTEGRNNDKYNFYSSVILFFIIYFFIFI
                     IESL"
BASE COUNT          219 a           45 c           65 g          221 t
ORIGIN      
        1 attgcataaa aatgattttt atataaattt taaacagaag aataaatttc taacgaaatt
       61 ggatatttct tctgtaaata catattcaaa aaaagaatta taagagttta gtcagcagtc
      121 gtgtaagtaa taaggacttt ataaatatat agaaatataa tgatatgagt ataagtagaa
      181 aaattttatg atttttacaa ttatttttta taaaaaggga ggttatgttt gttgaattta
      241 caatcaaaat gggtaaactt tttaaagcca acatatgtca gtgatgaaat aaaaagaaaa
      301 aaactacaag ttataatatt tttttctata acttatggtt tatcttattc actaggttta
      361 ttagcaatat gttttaatca tttaatagat tcagaaattt tagctcaatt tatgatgata
      421 ttgccattat cttcagtttc tattgcaaaa ttttacacag aaggaagaaa taatgataaa
      481 tataatttct attcatcagt aatattattt tttattattt acttttttat atttattatt
      541 gaatcattaa
//
LOCUS       DAMJWO010000208          500 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.214, whole genome shotgun sequence.
ACCESSION   DAMJWO010000208 DAMJWO010000000
VERSION     DAMJWO010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.214"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..363
                     /locus_tag="PC366_003740"
     CDS             <1..363
                     /locus_tag="PC366_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2579184.1"
                     /translation="LMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIASIIIGITL
                     FKKFTFIKDTTAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIVIIAFLATGNLNISL
                     KKTNAKLVPKINQKKEVL"
     gene            364..>500
                     /locus_tag="PC366_003741"
     CDS             364..>500
                     /locus_tag="PC366_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2579185.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KS"
BASE COUNT          178 a           71 c           77 g          174 t
ORIGIN      
        1 cttatgattt caaacggact tatagcttta tctggtagtc ttatggctca gttcttggga
       61 ttctcagatg taaatatggg tataggaact ttagttcttg gaattgcctc tatcataatt
      121 ggtattacac tatttaagaa atttactttt atcaaagata ctactgcaat aattgttggc
      181 tcttttatat accaattcac tatatacttt gcaatgagtt taggaatgtt atcaactgac
      241 ttaaaactaa taactgccat agttataata gctttcctag ctactggtaa cttaaatatt
      301 tcactaaaaa aaacaaatgc aaagctagta ccaaaaataa atcagaaaaa agaggtgttg
      361 tagatgttac aaattaaaaa tctttcaaag agtttcccta atccatatgg tgaacctaat
      421 actatctttg aaaatttatc aatcgatata gaagatggtg aatttgtaag tatcataggt
      481 agtaatggaa ctggtaaatc
//
LOCUS       DAMJWO010000209          475 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.215, whole genome shotgun sequence.
ACCESSION   DAMJWO010000209 DAMJWO010000000
VERSION     DAMJWO010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.215"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(<1..393)
                     /locus_tag="PC366_003742"
     rRNA            complement(<1..393)
                     /locus_tag="PC366_003742"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          126 a          114 c           75 g          160 t
ORIGIN      
        1 aagtcttctc gtttaacata caggactatt accttctgtg gtgggtcttt ccaaacctct
       61 tcaattacga tacctcttcg ttatgatatg tccgcaaccc caataaagaa aactttattg
      121 gtttgggcta atccgcgttc gctcgccgct acttacggaa tcgaatttct ttctcttcct
      181 tcaggtactt agatgtttca gttccctgag ttcccctcat taagctatgt attcacttaa
      241 tgatacttag acattactct aagtgagttt cctcattcgg aaatcttcgg atcaaagttt
      301 acgtgcaact ccccgaagct tatcgcagct tatcacgtcc ttcatcggct cctagtgcca
      361 aggcatccgc cctgcaccct taataacttg accagttaaa aaggtttgat agattagaag
      421 ctatcaactt cgataatttt aaaaagttat cagctttata tattacaaat tagat
//
LOCUS       DAMJWO010000210          460 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.216, whole genome shotgun sequence.
ACCESSION   DAMJWO010000210 DAMJWO010000000
VERSION     DAMJWO010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.216"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
BASE COUNT          200 a           46 c           55 g          159 t
ORIGIN      
        1 agacagtttt acatatttca actgtctcct aagaggggta tagttcacaa ctaagagtgg
       61 ctgggaactt aatataaagt tccagaaaag taaatcttca aaataattta ttgaaggaaa
      121 catcactcaa agttaagtaa aatatgtttc cttgctttta ttatatcaca aattaaaaat
      181 attaacacaa aattttgtga atatatactt attattgttc taaaaaaata tgtaaataat
      241 tgatttgatt tcatagaatt attgttgtaa tatttagtta aatatacaca atctcaatta
      301 aagaagataa gtattataaa ttcatatcaa aaaaatacat aaacttttaa gttataattt
      361 tataaaaagt cttttagtat cattatttca agaggaatta acatatgaaa aaataacttc
      421 attagaaaag tggataaaaa actggtaaga agatgactaa
//
LOCUS       DAMJWO010000211          420 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.217, whole genome shotgun sequence.
ACCESSION   DAMJWO010000211 DAMJWO010000000
VERSION     DAMJWO010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.217"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..>420
                     /locus_tag="PC366_003743"
     rRNA            <1..>420
                     /locus_tag="PC366_003743"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          106 a           97 c          130 g           87 t
ORIGIN      
        1 cgcctcccaa aaggtaacgg aggcgctcaa aggttctctc agtacggtcg gaaatcgtac
       61 gtagagtgta aaggcaaaag agagcttgat tgcaagacat acaggtcgag caaggatgaa
      121 aatcggactt agtgatccgg tggttctgcg tggaagggcc atcgctcaac ggataaaagc
      181 taccctgggg ataacaggct tatctccccc aagagtccac atcgacgggg aggtttggca
      241 cctcgatgtc ggctcatcac atcctggggc tgtagtaggt cccaagggtt gggctgttcg
      301 cccattaaag tggtacgcga gctgggttca gaacgtcgtg agacagttcg gtccctatcc
      361 gtcgcaggcg taggaaattt gagaagacct gtccttagta cgagaggacc gggatggacg
//
LOCUS       DAMJWO010000212          388 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.218, whole genome shotgun sequence.
ACCESSION   DAMJWO010000212 DAMJWO010000000
VERSION     DAMJWO010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.218"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            <1..>388
                     /locus_tag="PC366_003744"
     CDS             <1..>388
                     /locus_tag="PC366_003744"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDF2579186.1"
                     /translation="DLGDRSIVSYVIGKSNNNNLVFETFNKAIEVYPNAKPIFHSDRG
                     YQYTSRVFKSKLLTQGMIQSMSRVGHCIDNAPMEGFWGILKVEMYYLRKFDTYEQLVK
                     AIDDYIYYYNNFRYQKRLNSMSPLEFR"
BASE COUNT          150 a           44 c           68 g          126 t
ORIGIN      
        1 ggatttaggt gatagaagca tagtttcata tgttattgga aaatcaaata acaataactt
       61 agtattcgaa acttttaata aagcaataga agtatatcca aatgcaaaac ctatctttca
      121 tagtgataga ggctatcagt atactagcag ggtgtttaaa tcaaaacttt taacacaagg
      181 catgatacaa agtatgtcga gagttggtca ttgtattgac aatgctccta tggaaggatt
      241 ttggggaatt ttaaaagtgg aaatgtacta tttaaggaaa tttgatacat acgaacaatt
      301 agtcaaagca atagatgatt atatatatta ctataataat tttagatatc aaaagagatt
      361 aaattctatg tctccacttg aatttagg
//
LOCUS       DAMJWO010000213          382 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.219, whole genome shotgun sequence.
ACCESSION   DAMJWO010000213 DAMJWO010000000
VERSION     DAMJWO010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.219"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(33..326)
                     /locus_tag="PC366_003745"
     CDS             complement(33..326)
                     /locus_tag="PC366_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579187.1"
                     /translation="MISMIMMLIGVLFIVFGIILTAVEIKGKMPGFYGVGQNAVRKNA
                     IGIIAAGIALIFFRNGLDSIDSILTYGVFLVIELVVIGLYFLIRIKYDKDGNL"
BASE COUNT          149 a           76 c           20 g          137 t
ORIGIN      
        1 atatcaaaat caaaatatta ttaatttata ctttaaagat tcccatcttt atcatatttt
       61 attcttataa gaaaatataa tcctattact actaactcta tcactaaaaa tactccatag
      121 gtaagaattg aatcaatact atctaaccca tttctaaaaa aaattaatgc tatacctgct
      181 gctataatcc ctatagcatt ttttcttact gcattttgcc caactccata aaaacctggc
      241 atttttcctt ttatttcgac agcagttaaa attatcccaa acactataaa taatactcca
      301 ataagcatca taatcatact aatcatctaa ttacctcctt cacttaagga aatttcaatt
      361 tctaaaatct aaaataaata at
//
LOCUS       DAMJWO010000214          373 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.220, whole genome shotgun sequence.
ACCESSION   DAMJWO010000214 DAMJWO010000000
VERSION     DAMJWO010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.220"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            177..293
                     /gene="rrf"
                     /locus_tag="PC366_003746"
     rRNA            177..293
                     /gene="rrf"
                     /locus_tag="PC366_003746"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            300..371
                     /locus_tag="PC366_003747"
     tRNA            300..371
                     /locus_tag="PC366_003747"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:332..334,aa:Asn,seq:gtt)
BASE COUNT          118 a           61 c           80 g          114 t
ORIGIN      
        1 tttgatgtta ttcattaaga tatatgtgca gtttttagag tgttaactct atgtaaagta
       61 ctaacttcaa ttgatgaagt atatatcgta aaaacaatta ctatttagta cttcaaaact
      121 attgacattt aaaaataaag atgttaatat aatacttgtc ttataaatag gcaatatgtg
      181 gttataatag caaagaggat acacctgttc ccattccgaa cacagaagtt aagctcttta
      241 gcgctgatgg tacttggtgg gaaactgcct gggagagtag gacgtagcca cgtgaatatt
      301 ccaaggtagc tcaatggtgg agcaaccggc tgttaaccgg taggctgtgg gttcgagccc
      361 cacccttgga gcc
//
LOCUS       DAMJWO010000215          366 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.221, whole genome shotgun sequence.
ACCESSION   DAMJWO010000215 DAMJWO010000000
VERSION     DAMJWO010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.221"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(101..217)
                     /gene="rrf"
                     /locus_tag="PC366_003748"
     rRNA            complement(101..217)
                     /gene="rrf"
                     /locus_tag="PC366_003748"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(226..299)
                     /locus_tag="PC366_003749"
     tRNA            complement(226..299)
                     /locus_tag="PC366_003749"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(265..267),aa:Gly,seq:tcc)
BASE COUNT          128 a           76 c           57 g          105 t
ORIGIN      
        1 atcttcacta tatcatttat tgccaaaaaa atctataaaa gacaaataaa aacatataac
       61 aattgtaggt ttattaaatt taatacaaca aaaaaagatt acgtggctac gtcctactct
      121 cccaggcagt ttcccaccaa gtaccatcag cactagagag cttaacttct gtgttcggaa
      181 tgggaacagg tgtatcctct ctgctattgt aaccacataa tcttttggag cgggtgaagg
      241 ggatcgaacc ctcacagctg gcttggaagg ccagaactct accattgagc tacacccgca
      301 ttaaattttt ataaattagt aaaactaatt ttttagagtt agcaccctaa aaactacata
      361 tatatc
//
LOCUS       DAMJWO010000216          302 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.222, whole genome shotgun sequence.
ACCESSION   DAMJWO010000216 DAMJWO010000000
VERSION     DAMJWO010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.222"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
BASE COUNT          113 a           32 c           27 g          130 t
ORIGIN      
        1 gaacttaaaa ttaatatgga taaatattct aaacccagta tttattaaaa atgaaataaa
       61 aagaaaaaaa atacaaatta ttatcttttt ctttataaac tttggtttaa cttattcatt
      121 aggtttactg ttatattata ataaatttat tgatccagaa aactttgcat cattcatgat
      181 gatattacct ctatcttcag ttgctattgc aaagttttat actgaaggat taaataatga
      241 tatgtatgaa ttttattcac taatcatatt attttttctt atttattcat tattaattgt
      301 tc
//
LOCUS       DAMJWO010000217          241 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.denovo.223, whole genome shotgun sequence.
ACCESSION   DAMJWO010000217 DAMJWO010000000
VERSION     DAMJWO010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..241
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.denovo.223"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
BASE COUNT          124 a           18 c           30 g           69 t
ORIGIN      
        1 aataaatagg tttacttagc attaagtttt aaaaattaaa tataaagaat acatgataaa
       61 taaaaaattt aaaaaaagta aaaaattata ttgactagaa tagataaaga tgatatagta
      121 ttacttgtcc ttgaaaaaag gaaaaagaaa taaacacgaa cattgaaaat taaacagtag
      181 gttaatttat attaagaaac aaaccataaa gccagatatt ttgataacaa tagtatctga
      241 g
//
LOCUS       DAMJWO010000218       105741 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.guided.003, whole genome shotgun sequence.
ACCESSION   DAMJWO010000218 DAMJWO010000000
VERSION     DAMJWO010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 105741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 105741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..105741
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.guided.003"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            192..851
                     /gene="cprR"
                     /locus_tag="PC366_003750"
     CDS             192..851
                     /gene="cprR"
                     /locus_tag="PC366_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HDF2579188.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
     gene            1062..2120
                     /locus_tag="PC366_003751"
     CDS             1062..2120
                     /locus_tag="PC366_003751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDF2579189.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPKKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            2371..4515
                     /gene="fdhF"
                     /locus_tag="PC366_003752"
     CDS             2371..4515
                     /gene="fdhF"
                     /locus_tag="PC366_003752"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:2785..2787,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HDF2579190.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKTWGVKLSPNNGYSLTQVPDLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            4564..5397
                     /gene="fdhD"
                     /locus_tag="PC366_003753"
     CDS             4564..5397
                     /gene="fdhD"
                     /locus_tag="PC366_003753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HDF2579191.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNDKYVNTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNSLDYITCASVKSNIKINYDTIYSIMDRNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            5408..5581
                     /locus_tag="PC366_003754"
     CDS             5408..5581
                     /locus_tag="PC366_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579192.1"
                     /translation="MCTKKEEQKCSKCEICGVLIDDTDKVYNNTYNLCKKCKRNISTE
                     KIVKYINIYDESK"
     gene            5639..6190
                     /locus_tag="PC366_003755"
     CDS             5639..6190
                     /locus_tag="PC366_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2579193.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRHCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            6215..7591
                     /locus_tag="PC366_003756"
     CDS             6215..7591
                     /locus_tag="PC366_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HDF2579194.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            7591..8106
                     /locus_tag="PC366_003757"
     CDS             7591..8106
                     /locus_tag="PC366_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDF2579195.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNPDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(8184..9467)
                     /locus_tag="PC366_003758"
     CDS             complement(8184..9467)
                     /locus_tag="PC366_003758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugated bile salt MFS transporter"
                     /protein_id="HDF2579196.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSHSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     TISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKKLNKERLDKLMQ"
     gene            9655..10077
                     /locus_tag="PC366_003759"
     CDS             9655..10077
                     /locus_tag="PC366_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HDF2579197.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSEKNGENIIRDILDGNISSECENGIKSKSVIFNNTPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            10179..11117
                     /locus_tag="PC366_003760"
     CDS             10179..11117
                     /locus_tag="PC366_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDF2579198.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYIMENKPVDNVVDISRGY"
     gene            11303..13327
                     /gene="ligA"
                     /locus_tag="PC366_003761"
     CDS             11303..13327
                     /gene="ligA"
                     /locus_tag="PC366_003761"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HDF2579199.1"
                     /translation="MSVKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKDMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKANDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            13487..14836
                     /gene="rph"
                     /locus_tag="PC366_003762"
     CDS             13487..14836
                     /gene="rph"
                     /locus_tag="PC366_003762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HDF2579200.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRAIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKTIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEIADEILGMDYGNEVVIATNNAHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARAIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNVPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            14836..15306
                     /locus_tag="PC366_003763"
     CDS             14836..15306
                     /locus_tag="PC366_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDF2579201.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTNMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDDIKIEEIRI"
     gene            15500..16786
                     /locus_tag="PC366_003764"
     CDS             15500..16786
                     /locus_tag="PC366_003764"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HDF2579202.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            16935..17519
                     /gene="clpP"
                     /locus_tag="PC366_003765"
     CDS             16935..17519
                     /gene="clpP"
                     /locus_tag="PC366_003765"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDF2579203.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            17538..18788
                     /gene="clpX"
                     /locus_tag="PC366_003766"
     CDS             17538..18788
                     /gene="clpX"
                     /locus_tag="PC366_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HDF2579204.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(18859..19386)
                     /locus_tag="PC366_003767"
     CDS             complement(18859..19386)
                     /locus_tag="PC366_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF2579205.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(19374..19886)
                     /locus_tag="PC366_003768"
     CDS             complement(19374..19886)
                     /locus_tag="PC366_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HDF2579206.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            20066..22429
                     /gene="lon"
                     /locus_tag="PC366_003769"
     CDS             20066..22429
                     /gene="lon"
                     /locus_tag="PC366_003769"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HDF2579207.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFNSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLGNIPRPLLDRMEVIEVSGYIEEEKLNI
                     ARKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTAVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            22419..23030
                     /locus_tag="PC366_003770"
     CDS             22419..23030
                     /locus_tag="PC366_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HDF2579208.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(23295..24665)
                     /locus_tag="PC366_003771"
     CDS             complement(23295..24665)
                     /locus_tag="PC366_003771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2579209.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYALGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDISGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFIGLILTVFFMRK
                     TDKSIS"
     regulatory      complement(24840..24955)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            25243..26322
                     /locus_tag="PC366_003772"
     CDS             25243..26322
                     /locus_tag="PC366_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDF2579210.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKATEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     gene            26714..27394
                     /locus_tag="PC366_003773"
     CDS             26714..27394
                     /locus_tag="PC366_003773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HDF2579211.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSEEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            27387..28766
                     /locus_tag="PC366_003774"
     CDS             27387..28766
                     /locus_tag="PC366_003774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HDF2579212.1"
                     /translation="MINIILEESSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGVLLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            28937..30022
                     /locus_tag="PC366_003775"
     CDS             28937..30022
                     /locus_tag="PC366_003775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HDF2579213.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKVKNLLSIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISTVVTNNLAYIIFSFILFSIGSIYFFITNDNIKKLINSLKFKIPF
                     IKKINQLVATTRFSRALSVLISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANVFPKLFISMANTGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            30076..30435
                     /locus_tag="PC366_003776"
     CDS             30076..30435
                     /locus_tag="PC366_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HDF2579214.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            30488..31360
                     /locus_tag="PC366_003777"
     CDS             30488..31360
                     /locus_tag="PC366_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HDF2579215.1"
                     /translation="MAIIKKILNLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIVIRNVEVLNTKKKRDI
                     LSMIEFEITQYIPININNYSIKYKVINSKNDKLNIQVILFPKSIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIRETYLLSKEGK
                     SYEFIKRLLRDFKYVYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNFDADLE
                     DNRINYINSIGMII"
     gene            31361..31804
                     /locus_tag="PC366_003778"
     CDS             31361..31804
                     /locus_tag="PC366_003778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579216.1"
                     /translation="MKVDKTINFLNGFKKTKPCNKIYKIIIVLILTCILFKSFMYVKS
                     INELEDYINQNKLVDKSKHTLPTTDKTREKFSKIKLNEIKKIYETIGINSITKISIDK
                     NKLEMEGVCSDLDVLNNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            31819..32403
                     /locus_tag="PC366_003779"
     CDS             31819..32403
                     /locus_tag="PC366_003779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579217.1"
                     /translation="MRLNNREKNLLKILLILVIILASDIAVSYLEENLTSLKNEKQNI
                     INKINNQDNYQIKDNKHIDDKYIESVELNKNEELKNNFNNSFLDKKTNKDIVLLVENE
                     LRDIVNVEYINQESSLDNHNKKQVNLEIKVNGELANVLKLEGVMKKLRLNNKLEKIEI
                     NKLKVNNFDVQNIPNEYKQEKDNIVECKMTVRVI"
     gene            32656..33693
                     /locus_tag="PC366_003780"
     CDS             32656..33693
                     /locus_tag="PC366_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HDF2579218.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLSGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            33774..34139
                     /locus_tag="PC366_003781"
     CDS             33774..34139
                     /locus_tag="PC366_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579219.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINVAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            34144..34461
                     /locus_tag="PC366_003782"
     CDS             34144..34461
                     /locus_tag="PC366_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579220.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            34509..36113
                     /locus_tag="PC366_003783"
     CDS             34509..36113
                     /locus_tag="PC366_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579221.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVVLKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYINVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            36237..37865
                     /locus_tag="PC366_003784"
     CDS             36237..37865
                     /locus_tag="PC366_003784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HDF2579222.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTNLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIAKTYRRERLINDLQKAILNYLL
                     KLSKAPLDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNISFSEEGQSELD
                     VMYNRVVSAYTYALESMRTDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            38130..39479
                     /locus_tag="PC366_003785"
     CDS             38130..39479
                     /locus_tag="PC366_003785"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HDF2579223.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSAEKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            39635..40714
                     /locus_tag="PC366_003786"
     CDS             39635..40714
                     /locus_tag="PC366_003786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDF2579224.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
     gene            41059..41967
                     /locus_tag="PC366_003787"
     CDS             41059..41967
                     /locus_tag="PC366_003787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HDF2579225.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGVNIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
     gene            41972..44341
                     /locus_tag="PC366_003788"
     CDS             41972..44341
                     /locus_tag="PC366_003788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HDF2579226.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKKDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFQSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRLTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPKDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            44666..45469
                     /gene="proC"
                     /locus_tag="PC366_003789"
     CDS             44666..45469
                     /gene="proC"
                     /locus_tag="PC366_003789"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDF2579227.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAEDITVSDLSQVALDKV
                     KEEFGINTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
     gene            46067..48823
                     /locus_tag="PC366_003790"
     CDS             46067..48823
                     /locus_tag="PC366_003790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2579228.1"
                     /translation="MRDEILSFVNECVLFNNFDELKKESGIITEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYDNSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSKFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNTILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEIFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALESKL
                     LIYLKKESYKEYSIISKISTLITNRLDMYLNNVDTIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKNKINGPMLFIDQISTISALEVGNLLMQGKNIEQIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGTAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVMAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLPNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
     gene            48955..49434
                     /locus_tag="PC366_003791"
     CDS             48955..49434
                     /locus_tag="PC366_003791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDF2579229.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTRDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKEIGDLGIDIELRMLPRDKKKQLSDLIK"
     gene            49450..49872
                     /locus_tag="PC366_003792"
     CDS             49450..49872
                     /locus_tag="PC366_003792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HDF2579230.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLANIEYFCMTKDKSADDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSIFL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENRNKIKNVM"
     gene            49912..50703
                     /locus_tag="PC366_003793"
     CDS             49912..50703
                     /locus_tag="PC366_003793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDF2579231.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMFDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTTLINAIPKVILDGLGVAGTLLPAVGFALLMDMLISKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAMNTLTEGEIDFE"
     gene            50696..51496
                     /locus_tag="PC366_003794"
     CDS             50696..51496
                     /locus_tag="PC366_003794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDF2579232.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     KVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFLIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            51544..52599
                     /locus_tag="PC366_003795"
     CDS             51544..52599
                     /locus_tag="PC366_003795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDF2579233.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKRANLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGTISSEKYNEEINKILDAINRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGVDPSV
                     PKDTRFHMKLGSKKLNK"
     gene            complement(52759..54705)
                     /gene="feoB"
                     /locus_tag="PC366_003796"
     CDS             complement(52759..54705)
                     /gene="feoB"
                     /locus_tag="PC366_003796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDF2579234.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIMEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKSNTH"
     gene            complement(54723..54941)
                     /locus_tag="PC366_003797"
     CDS             complement(54723..54941)
                     /locus_tag="PC366_003797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDF2579235.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            55147..55656
                     /locus_tag="PC366_003798"
     CDS             55147..55656
                     /locus_tag="PC366_003798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HDF2579236.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            55734..55895
                     /locus_tag="PC366_003799"
     CDS             55734..55895
                     /locus_tag="PC366_003799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HDF2579237.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            56046..56711
                     /locus_tag="PC366_003800"
     CDS             56046..56711
                     /locus_tag="PC366_003800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDF2579238.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            56777..58561
                     /gene="pepF"
                     /locus_tag="PC366_003801"
     CDS             56777..58561
                     /gene="pepF"
                     /locus_tag="PC366_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDF2579239.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYTKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEKYL
                     KVIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLIHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGEPLTADEFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            58813..59655
                     /locus_tag="PC366_003802"
     CDS             58813..59655
                     /locus_tag="PC366_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDF2579240.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCSSNSGGSGDSGDSSKVSVSGS
                     TSIGPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSA
                     GLKETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREE
                     GSGTRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSL
                     KINDVEATDANVMANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFI
                     KVNQ"
     regulatory      59888..59971
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            60551..61228
                     /locus_tag="PC366_003803"
     CDS             60551..61228
                     /locus_tag="PC366_003803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2579241.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVERI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     gene            61300..63315
                     /locus_tag="PC366_003804"
     CDS             61300..63315
                     /locus_tag="PC366_003804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDF2579242.1"
                     /translation="MKKYNILKGTLIVLIVSLLAIAGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGN
                     QSPYGNATYRMRIKNEGEDKLLSLELPEIFSASEVWINGEIVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKDTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKLYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDSSY
                     FMVVLCIICINGSISKIEEDKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFIIVILFSLMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KKFLADVAHDLKAPVSAIQSFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNDFIKEIYENNLPDTQACGVNFETYILEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKVSDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            63365..64045
                     /locus_tag="PC366_003805"
     CDS             63365..64045
                     /locus_tag="PC366_003805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2579243.1"
                     /translation="MQTKILIIDGDKDNCQKLKGFLEEKEISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILTDGDGWTLCKKIRNVTTCPIVYMTYINEEQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            64427..65125
                     /gene="vanR"
                     /locus_tag="PC366_003806"
     CDS             64427..65125
                     /gene="vanR"
                     /locus_tag="PC366_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanR-ABDEGLN family response regulator
                     transcription factor"
                     /protein_id="HDF2579244.1"
                     /translation="MSGKILVVDDERDIADLIEVYLTNENYIVYKFYSGLDALNCINL
                     NEFDLAILDVMLPGVNGFSLCQKIREKYTYPIIMLTAKDEETDKITGLTLGADDYVTK
                     PFRPLELVARVKAQIRRYKKYSGSLQSGEELSHIFSFLGLELNTQTYECHLNGKALSL
                     TPTEFSILHVLLKNKGSVVNSENLFHAIWKDEYYNKSNNTITVHIRHLREKLGDTVDE
                     AKYIKTIWGVGYKI"
     gene            65161..66276
                     /locus_tag="PC366_003807"
     CDS             65161..66276
                     /locus_tag="PC366_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2579245.1"
                     /translation="MKKINNFTYRKLRDKYKFIKREKNTEAYLKYKLYIMLAIYTGIV
                     LVLMFMADYTFSNFSNPLVKWLKLRRDVLFFLVFIIGYITIFNFYWKKPWNYLREIIN
                     ATHTIYQQNDELVELSKPLKEIEQQMNQIKMSVLLSQQAVKEAENKKNNLVMYLAHDI
                     RTPLTSVIGYLSLLKEIPNMDNSQKSKYTEVALDKAQYLEKLINELFEITRYNSNQIK
                     INFEKVDLYYMLLQLKDEFYPLLSEKGNRAILKANESLTIKADSEKLARVFNNILKNA
                     IAYSYPNTEIIISAVHKDSKVDIAFRNYGQTIPEEQLSAIFEKFNRLDEARKSDMGGA
                     GLGLSIAKEIINLHGGDITVQSKDEVTTFTISLPTSI"
     gene            66421..67308
                     /locus_tag="PC366_003808"
     CDS             66421..67308
                     /locus_tag="PC366_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2579246.1"
                     /translation="MELKIEHVTKKFKDKIAVEDVCLTLTPGVWGFLGANGAGKTTLM
                     RIITDIMKPTNGKILYNGKNIYIMGAEYRNLLGFLPQEFGFPQDFSVKDYLEYIAALK
                     DVPPREVKGKINNLLEILTLSDVKNKKIIKLSGGMKRRVGIAQAMLNDPKILIMDEPT
                     AGLDPGERVRFRNFISEFSHNRVVLISTHIVSDIEYISTQNAIMKSGKILDVGTTDKL
                     VKKVEGKVWECLISNRDISKYEMNLRIINQRSEKNNQVSIRYLAEKSQIDNSIAVEPR
                     LEDLYLWLFPEAVYSKEGK"
     gene            67309..68544
                     /locus_tag="PC366_003809"
     CDS             67309..68544
                     /locus_tag="PC366_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2579247.1"
                     /translation="MRIFYLEIKRVLHSRRTLILLLLALVLSALMAFLPITYEGINYL
                     DNNGKVVELSGLDAIKYKKTIYANNSEISSGVVTPKKLKHALNIWKKTEEKYGKVGSE
                     DFPLDIYSKSILPIRPLLNRLPEAFANSETGFATELSEINTNDLDSFYEQCKTHLNDI
                     MKIERQTSSAQMKAQELYRKVDTPFEIYPGYSKDAFDYIIFYIFILLIICVAITAPTF
                     SGEYQTQSDSILRCTKHGHTRLAFTKILALFSIFIVMFVVCISIHLAISDLAFGTECL
                     KTSFQMLFSVISLVNINLLQAQILIAIGGLISILAMVSLTLFLSAKCKDSLTSMLIAF
                     SICLIPMGIGVSWIGYLLPPGGIGLKISLLYQMTSFNFLHLGGMSFWTPHIILFFSVI
                     EIPIFIFLAIRTYCKHQVS"
     gene            68926..69843
                     /gene="pstC"
                     /locus_tag="PC366_003810"
     CDS             68926..69843
                     /gene="pstC"
                     /locus_tag="PC366_003810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HDF2579248.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            69845..70669
                     /gene="pstA"
                     /locus_tag="PC366_003811"
     CDS             69845..70669
                     /gene="pstA"
                     /locus_tag="PC366_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HDF2579249.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVIIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            70688..71452
                     /gene="pstB"
                     /locus_tag="PC366_003812"
     CDS             70688..71452
                     /gene="pstB"
                     /locus_tag="PC366_003812"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDF2579250.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            71480..72133
                     /gene="phoU"
                     /locus_tag="PC366_003813"
     CDS             71480..72133
                     /gene="phoU"
                     /locus_tag="PC366_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HDF2579251.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            72291..73160
                     /locus_tag="PC366_003814"
     CDS             72291..73160
                     /locus_tag="PC366_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDF2579252.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGNYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            73247..74683
                     /locus_tag="PC366_003815"
     CDS             73247..74683
                     /locus_tag="PC366_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HDF2579253.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            74731..75558
                     /locus_tag="PC366_003816"
     CDS             74731..75558
                     /locus_tag="PC366_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2579254.1"
                     /translation="MKIKDNKAVFHVFIRIFLIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     misc_binding    75859..76121
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            76197..78863
                     /locus_tag="PC366_003817"
     CDS             76197..78863
                     /locus_tag="PC366_003817"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HDF2579255.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKAHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKVKKEKFEEMIKSVEERLTNLESKIK"
     gene            79288..79998
                     /gene="rgaR"
                     /locus_tag="PC366_003818"
     CDS             79288..79998
                     /gene="rgaR"
                     /locus_tag="PC366_003818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HDF2579256.1"
                     /translation="MFRVVICDDEKIQRSILKEFTKKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNMITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
     gene            81044..82075
                     /locus_tag="PC366_003819"
     CDS             81044..82075
                     /locus_tag="PC366_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HDF2579257.1"
                     /translation="MENICDMNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYI
                     FISDKFDDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNI
                     RLINLSLSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFT
                     LDGDDSFWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEK
                     PGITISDLNDKLESLATRNHWDSCDFDECSRIVNFKLDLYDKENALLMKVADVVRDCL
                     DIEDNNEKLFKGSLFNKEIGLVYDNCFNLLKKLEHRFDIKFNYMDISKYDLVSIYTLT
                     ELVERYKNL"
     gene            82208..83506
                     /locus_tag="PC366_003820"
     CDS             82208..83506
                     /locus_tag="PC366_003820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HDF2579258.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKETYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLPHFNKVITTTPNNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(83620..83865)
                     /locus_tag="PC366_003821"
     CDS             complement(83620..83865)
                     /locus_tag="PC366_003821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HDF2579259.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            84013..84879
                     /locus_tag="PC366_003822"
     CDS             84013..84879
                     /locus_tag="PC366_003822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HDF2579260.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            complement(84883..85419)
                     /locus_tag="PC366_003823"
     CDS             complement(84883..85419)
                     /locus_tag="PC366_003823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HDF2579261.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(85609..85812)
                     /locus_tag="PC366_003824"
     CDS             complement(85609..85812)
                     /locus_tag="PC366_003824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HDF2579262.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            86103..86867
                     /locus_tag="PC366_003825"
     CDS             86103..86867
                     /locus_tag="PC366_003825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDF2579263.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKYDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKKTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            87256..88569
                     /gene="prdC"
                     /locus_tag="PC366_003826"
     CDS             87256..88569
                     /gene="prdC"
                     /locus_tag="PC366_003826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HDF2579264.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     gene            88738..88900
                     /locus_tag="PC366_003827"
                     /pseudo
     CDS             88738..88900
                     /locus_tag="PC366_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011020315.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            89370..91130
                     /gene="prdR"
                     /locus_tag="PC366_003828"
     CDS             89370..91130
                     /gene="prdR"
                     /locus_tag="PC366_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HDF2579265.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
     gene            91559..93439
                     /gene="prdA"
                     /locus_tag="PC366_003829"
     CDS             91559..93439
                     /gene="prdA"
                     /locus_tag="PC366_003829"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HDF2579266.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            93520..93804
                     /locus_tag="PC366_003830"
     CDS             93520..93804
                     /locus_tag="PC366_003830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579267.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            93842..94567
                     /gene="prdB"
                     /locus_tag="PC366_003831"
     CDS             93842..94567
                     /gene="prdB"
                     /locus_tag="PC366_003831"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:94292..94294,aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HDF2579268.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            94647..95405
                     /gene="prdD"
                     /locus_tag="PC366_003832"
     CDS             94647..95405
                     /gene="prdD"
                     /locus_tag="PC366_003832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HDF2579269.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            95420..95887
                     /locus_tag="PC366_003833"
     CDS             95420..95887
                     /locus_tag="PC366_003833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HDF2579270.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            95905..96387
                     /locus_tag="PC366_003834"
     CDS             95905..96387
                     /locus_tag="PC366_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HDF2579271.1"
                     /translation="MSFVGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSE
                     HNEWKTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPAVGLTIM
                     GADGLVITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKALAFLKLKMRKDAK
                     "
     gene            96407..97414
                     /locus_tag="PC366_003835"
     CDS             96407..97414
                     /locus_tag="PC366_003835"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HDF2579272.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            97534..98415
                     /locus_tag="PC366_003836"
     CDS             97534..98415
                     /locus_tag="PC366_003836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HDF2579273.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGVKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
     gene            99083..99718
                     /locus_tag="PC366_003837"
     CDS             99083..99718
                     /locus_tag="PC366_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDF2579274.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
     gene            99902..100471
                     /locus_tag="PC366_003838"
     CDS             99902..100471
                     /locus_tag="PC366_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDF2579275.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            100549..100686
                     /locus_tag="PC366_003839"
     CDS             100549..100686
                     /locus_tag="PC366_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579276.1"
                     /translation="MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNK
                     E"
     gene            100683..102458
                     /locus_tag="PC366_003840"
     CDS             100683..102458
                     /locus_tag="PC366_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDF2579277.1"
                     /translation="MMVMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDVCRECYKSGACVEFAEVCCPIICD
                     GDSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLEKMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            102883..104190
                     /locus_tag="PC366_003841"
     CDS             102883..104190
                     /locus_tag="PC366_003841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HDF2579278.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDAAEKAESLMDTVTIQELIKNVEEIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDEKLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            104518..105057
                     /gene="hpt"
                     /locus_tag="PC366_003842"
     CDS             104518..105057
                     /gene="hpt"
                     /locus_tag="PC366_003842"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDF2579279.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGKVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            105435..>105741
                     /locus_tag="PC366_003843"
     CDS             105435..>105741
                     /locus_tag="PC366_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HDF2579280.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGATGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGANGTTGSTGPTGNTGATGANGITGPTGATGATGA
                     "
BASE COUNT        42524 a        11355 c        18952 g        32910 t
ORIGIN      
        1 agtaaatgcg tgtaaaatga atataaagtt tttgaaatat aaagtttttg tatctaaaat
       61 attttatttg taaaatagta attaattatt gtaagctata atatgagagt attatggtta
      121 atgtgaattt taaagatatt attaaagata taaattagaa tactattaaa cggataaatg
      181 gaggagttat tatgtctaag atattagtag tagatgatga gttagatatg ttaaagttga
      241 ttgaaaatgt gttgaaaaga gatggacatg aagtaaaggt aattagtgat gtagaaaagg
      301 ctatgaacat ggattttaat tattttaatc taataatatt agatgttatg atgcctaaga
      361 tggatggttt tgaagtatgt aaaactataa gaaataaggt tgattgtcca atactgtttt
      421 tgacagcaaa aaatatggaa agtgatatta tgtacggtct tggcataggt gcagatgact
      481 atataaccaa accttttggt gtaggagaat taagggctag gataactgct catttaaggc
      541 gagaaagtag agaaaaaaag aatttattaa ctatctcaaa tgttcaattt aactttttag
      601 gcaaagaagt ttcaattgat ggtaaaaaaa ttaattttac taaaagtgaa tatctaatat
      661 gtgaatttct agcaaaaaat aagggacaag tattttcaaa agaaagaata tatgagtcgg
      721 tatatggttt tgatggagaa agtgatataa gtactatcac agagcatata aaaaatatac
      781 gaagcaaatt aaaacaatat gatatttata caatagaaac tgtatggggg atagggtata
      841 aatgggtgta ataagtataa gtgttgctta gtgaaaatat tatatatatc tacaaaatgt
      901 ttgtaaaata ttaatctata tattaaaatt taatttatag attaatattt tttgtaaatg
      961 acaaaattgt aaggtatttt gttataaaat attaagattc atagtgtata ctaataatat
     1021 agtatttagt ataaatcttg agcaaaggat ggttatttct aatggataga ctaaagaata
     1081 ttagaaagag tttactacag tatacatttt tatttttgtt aataggtata acaatttacc
     1141 tagtgtttaa aacattggat attaaaatgc tatcaaatgt tatggttatg gtagataaga
     1201 agtttttatt cataggtgct ttggcaataa tgtgtcacat aatgcttgaa ggagtagtaa
     1261 tgaagataat tatagaaagc actcacaaag ttaatattag atttattggt tttaagctag
     1321 ccattatggg attttattat aatttaataa ctccttttgc ttcaggaagc caaccagtac
     1381 agatatatgt acttaaaaaa tgtaaaatgc cacttagtaa ggcaagtgca gttgttacca
     1441 ataagtctat tattttccaa atagtggtta ctttttattg tacaatactt gtattaatga
     1501 attttgctat gttagaaaaa caaatgaaaa tgattatgcc tctagtgttt ctagggatag
     1561 ccattaattc atttgtctta attatgataa tattagttat tttaaaccct aaaaaaataa
     1621 aatattttat gagaattact ataaagcatt tatcaaaaat taagttttta aaatttttag
     1681 ataataagat tgaatccata gaaagtttta tagatgatta tagtaaagca ataaattttt
     1741 ttgcaaagaa taaaaaggta ttaatttcaa ctataatagt aacttttatt caattaagtg
     1801 cttactttag tgtttcattt tggatatata aagcatttaa tttacaaggt tatagctata
     1861 tttatatact gacattacaa gcatttttat atatggcaat atctccaata ccaacacctg
     1921 ggaatgtagg agctaatgaa ttagcctttt tcactatatt caaatcagta ttccctcaac
     1981 ctttgatggg atatgcagta tttttatatg gtggatttat gtactattta attctgattg
     2041 gaagtggaat atttactgta attactcact atagaatgaa aaatagaatt ggcagaaata
     2101 ttgttttaag tgaaaactaa ataagtttaa agaatatata ttgagtatat taaaaaatat
     2161 gtcataagaa ctagaatatt ttaattaaat ggttgaaata taaagattat tatgacatat
     2221 tttttttgaa atttaagagg aattgtgaga aaattgttga atttaataga tagtattgca
     2281 aaatatttat gattttgcat attataaaaa cactcattat ctttaagata aattttactt
     2341 atcaggggat aaatctaagg ggggaattgt atggagaaaa aaattttaac agtttgtcca
     2401 tactgtggag ctggatgcca attatatcta gtagtaaaag ataataagat attaagagct
     2461 gaaccggcta atggtagaac aaatcaagaa agtttgtgtt taaaaggtcg ttatggatgg
     2521 gattttctaa atgaccctaa aattctaaca cctaggctaa aaaagccaat gataagaaaa
     2581 caaggtgtac tagaagaggt tgaatgggat gaggctataa actatacagc ttcaagacta
     2641 aatgaaatta aagaaaaata tggacctgat tctattatgg gaacaggttc tgcaagagga
     2701 cctggtaatg aagcaaacta tataatgcaa aaatttatga gagctacaat aggaactaat
     2761 aatgttgacc attgtgctcg tgtatgacat gcaccatctg tagccggtct ggcttactca
     2821 ttaggtagtg gtgcaatgtc taattctata ccagagatag aaaatgcaga tgttttattt
     2881 atatttggat ataatggagc agattcacat ccaatagtgg caaatagaat agtaaaagct
     2941 aaaaaaaatg gtgctaaatt aattgttact gaccctagag taactgaatc tgcaagaatt
     3001 gctgatatac atctacctat aaaaggtgga acaaacatgg ttttagtaaa tgcttttgga
     3061 aatgtattaa tagaagaagg tctttacaat aaagaatttg ttcaaaatca tacacaagga
     3121 tttgatgagt ataaagaaat tgttaaacca tatacagcta aatatgctga aaagattaca
     3181 ggaatcccag aagagcttat aagaaaagct atgagagaat atgcaaaagg gaaaaaagct
     3241 atgatacttt atggaatggg tgtctgtcaa tttggtcaag ctgttgatgt agttaaggga
     3301 cttgcatcaa ttgctctact tacaggtaat tttggtagag aaagcgttgg aataggacct
     3361 gtacgtggac aaaataatgt tcaaggagct tgtgatatgg gagctcttcc taatgtatat
     3421 cctggctatc aaaatgtaac tgatgataag ataagagaaa agtttgaaaa aacttggggg
     3481 gtaaaattat ctcctaataa tggttatagt ttaactcaag ttccagactt agtactaaaa
     3541 gagaaaaagc ttaaagctta ttatatattt ggagaagacc cagtgcaaag tgacccagat
     3601 gcatcagaag ttagagaagc attagatgaa ttggaatttg tcattgttca agatatattt
     3661 atgaataaga cagcacttca cgctgatgtt atacttccag ctacttcttg gggagaacat
     3721 gagggagtat atacatgtgc agatagagga ttccaattga tgagaaaagc tatagagcca
     3781 caaggagatg taaaaccaga ctggcaaatt ataagcgaaa tttctacagc aatgggatat
     3841 cctatgaatt ataaaaatac taaggaaata tgggacgaac ttagacaatt atgtccaagt
     3901 ttcttaggtg ctacttatga aaagatagaa actcaaggat gcgttcaatg gccttgtaag
     3961 agtgaaagta tggaagataa aggaactatg tatctgtatg aaggtcaaaa gttttctact
     4021 cctaatggta aaggtaattt gttcgctgct gaatggagac cccctatgga agttgaagat
     4081 gatgaatacc catttagttt atgtactgta agagaagttg gacactattc agtaagaaca
     4141 atgactggta attgtagaac acttagttca ttagaagatg aaccaggacg tgttcaaata
     4201 aattctaatg atgctgaaaa attaggaatt gaagatgatg aattagttag aattagttca
     4261 agaagaggaa gtgtaataac aagagcaaca gttactgata gagttaagga aggtgcaaca
     4321 tatatgactt atcagtggtg ggttggagct tgcaatgaac ttacaatagc aaatttagac
     4381 cctatatcta aaacaccaga gtataaatat tgtgctgtta aacttgaaaa acttgaagac
     4441 caagaattag cagaaaaatg tgtaagagaa gagtatcaaa gtttgaaaga caaaatgaca
     4501 gctacaaata tctaatgatt tattagattt aagatttata aaaggcagaa aggctaatat
     4561 tttatgaaca atatatactc aaaaactaaa ttacaagaaa atagtaagga taaagttttt
     4621 gaaaatagtt atagtctagt ggactacaaa tatttaaatt cttttaatgt agaagtaagc
     4681 aaaataaatg aacatgaagt atcaatagat aatgaagaaa taattgcaga atatccactt
     4741 agttttattt taaatgataa atatgtaaat acatttttat gtaccccata taatttagag
     4801 gaacttatag taggattctt gaaaacaaaa ggatacatag aaaacaaaaa aagcttatta
     4861 aaatttgaga taaatgagag tgaacgtttt gcaaaagtaa ctattcaaga gaaacaaaaa
     4921 aatcaagatg agcaaattat atttttaaat tcactagact atataacatg tgcttctgta
     4981 aagagcaata taaaaataaa ttatgatacg atttacagta taatggatag aaatttaaat
     5041 tcatcagaat tatttaaaaa tactggtggg gtacatagcg tatctgtatt taattttgat
     5101 aaaaaaatag tcacttgtga agatgtagca aggcataatg caatggataa ggctattgga
     5161 ttttgtgttt taaatgacat aacattaaaa gataaaattg tggctgtaag tggaagaata
     5221 tcattggaaa tgatattaaa agcagctatg actcaaattc ctattgtagt atcaaaatca
     5281 gcaccgacta atttatcaat agagctttct aaaaaattaa atataacgct tattggattt
     5341 gtaagaggaa gacggatgaa tatttatgca aatccacaga gagttatcaa aaagtgagaa
     5401 taagtatatg tgtactaaaa aagaagaaca aaaatgttca aagtgtgaaa tctgtggagt
     5461 attaattgac gatactgata aggtgtataa taacacatac aatttgtgca aaaaatgtaa
     5521 acgaaatata agtactgaga aaatagtgaa atatataaat atatatgatg aaagtaagta
     5581 gacatatgat gaaagtaact agagggttgg aaatatacaa attgaaaggt gggataatat
     5641 gaaaaataaa ataggctctt ttgtaatagc ggacccaaac aaatgtacag gttgtagagc
     5701 ttgtgaagta gcttgtttta caatgcataa tcagcataat aatgtgggtt atacagttgg
     5761 aacagttgat atacctgtta tacctagact ttatttagta aaaggtgaca atttctgtat
     5821 gccaatacag tgtagacatt gtgaagatgc tccttgttta aactcatgtc cacaaaaagc
     5881 tatagtcaaa gaaaacaata ttatgtctgt aaatgaagaa aagtgtatag gatgtaaaac
     5941 ttgtctgcta gcatgtcctt ttggagctat agacttactt ccacaatatg aagatggtaa
     6001 agaagtagaa caagtaattt tagatgaaaa taagaagata gcttataaat gtgacttatg
     6061 taaagacaat gaaaaaatag cttgtataag tgcatgtcct caggaagcat taaaacttgt
     6121 tactccaata gatgacaaaa aagctaagaa tagacaagct gcacttagtt tattgttaac
     6181 aaataaataa aggatacagg ggtaggtgac gtttatgata ataaatatag ataaggattt
     6241 atgtactgga tgtagagaat gttcaaaggt ctgtccagta aatgctattg aaggtgaaga
     6301 gggaaagcca caagagataa atttagatag atgtgttatg tgcggtcaat gtgttcaaac
     6361 ttgtaaatct tatgcctcag ttatagatga aggatttgag tttttacaag agaaaaaaca
     6421 agaaagagag ataccagagt ctataaatga acctatattt gcagcataca atgtatgtga
     6481 tatagataag gtaaagaaag ctttaagtga cccaaatgta ttcactatgg tccaatgtgc
     6541 accagcagtt agagttgctt taggagaaga tttcggatat tatttaggat acttaggtgc
     6601 tggaaaaatg gcagcagcac ttagagcttt aaattttgat agagtctacg atactaattt
     6661 tgcagcagat ttaactataa tggaagaagg tagtgaatta attaaaagag tgacagaagg
     6721 tggaactctt ccaatgttta catcttgttg tccagcttgg gtaaaattca tggaaaaaaa
     6781 ttatcctaaa ttaactaatc atttatcttc ttgtaaatca cctcagcaga tgggtggtgc
     6841 aatatttaaa acttatggtg cagagataaa taatgtagat gcatcaaaga tatttagtgt
     6901 ttctataatg ccatgtacat gtaaaaaata tgaatgtgat agagaagaaa tggattctag
     6961 tggatataga gatgtagatg tagtattaac tactagagaa ctagcttatt taataaaaga
     7021 catgggaatt gattttaaaa atttaagaga agaaaaattt gatagtcctt taggtagtta
     7081 tagtggagct ggaactatct ttggtgttac tggtggggtt atggaagctg ctataagaac
     7141 aggatatgag cttataactg gagaaagtat tcctgatgta gaagtaaaac aagtaagagg
     7201 agaaaatggt tttagaaagt caactattaa aataggagac ttagacttaa gagttggagt
     7261 agtaagtgga ttaaaaaatg taataccagt gcttgaagac ttggaaaaag gaaaattaga
     7321 tgtagatttt attgaagtta tgacttgtcc tgttgggtgt gtaagtggtg gaggtcaacc
     7381 aaaaatttta ctagaagaat ataaggaatt ggcttatgaa aatagaacaa aagcaacata
     7441 cgtgcatgat gaacatttag caattagaaa atctcatgag aatcctgata ttaaaaaact
     7501 gtatgatgaa tatctggtag aaccattagg agaaaaatct catcatctat tacacactac
     7561 atattgtata ggaaaggaag tggctaagtg atgaactatt ttgttatagc agaccctgat
     7621 aaatgcatag gatgtagaac ttgtatgata ggatgtgtag ttgcacattc agatgaagat
     7681 attttttacc aaaatccaga tgaaataaat tttaatccaa aactttctgt cataaagaca
     7741 aaagaagtaa gtgctccaat acagtgtaga cattgtgaag atgctccttg tgcaaaggca
     7801 tgtccaaatg gtggtatagt tagggttggg aacacaataa aaataaatga agaaaattgt
     7861 ataggatgta agacttgtat gttagcatgt cctataggtg caatagacat agttacatta
     7921 aaagatgtag atgaaggaaa gctttgcttt agagaaagaa tgacagcaaa taagtgtgat
     7981 ttttgtatag aatcgccaga agggcctgca tgtgtaaatg tttgtccaac taaggcattt
     8041 actatagtta aggatgagga tatagatagt aaagttaaaa ataagagaaa attagctata
     8101 ttgtaatata aaaaagatgg agttttattt atgattaaaa gctccatctt ttttattata
     8161 atatttatat atctaaaaat caattattgc attagtttat ctaatctttc tttattcaat
     8221 tttttcattc ctatagaagt tataataagt aaagtatagg caattataac tgataaaatt
     8281 ataatagacc aagaaaatct gtatccaaaa ttatcaacta acaatccaaa taatgttgaa
     8341 cctaatgcaa atcccactgc aaaaattaat tgtacgattc catatatgct accaaactcc
     8401 ttttgaccaa agaaagagcc agttaaataa gcaggaccaa tcatataagc aaatacagaa
     8461 agacctttca aaatggcaaa tacaaatgca aaagtagaag atttatctac caatagtaat
     8521 gataaagttg ctataagaac caatacaaaa gatataataa gtggctttgt ttgaccgaat
     8581 ttatcaaaca ataatcctcc aaataaatta ccaatgagag caaataaagc aaatgtggag
     8641 cctactgttc ctattagaat aggatttaga taatttctaa gataagttgg atattgtacg
     8701 gataatgatg aaacatatat accaacaaat ataaatccaa tagtcataat ccaaaaatat
     8761 ttaatttttt tagcttcttt taatgtataa ccccatactg aaggagaaat tgtatcagat
     8821 gctttctctt ttttaccttt agattttacc ttttcattaa tatctttagg catcctgagt
     8881 atgaataata ttacaggtat accaactatt aatgctataa ttccaaatat tagataagaa
     8941 tgactgtatc cttgagttgc taataagcga actgcaagtg gttgtagaaa tatactacca
     9001 atagaaccac cagcaaaagc aaagcccaaa gcttttcctt tgctttcttc atcaaaccaa
     9061 gcacttatta aaacaggtat tcctatagca gatataattg tagcgccaat ttgaacaata
     9121 catgatacag tgtaaaattg ccatagttca gtacatatag aaaaagtagc aaaagcaata
     9181 ctagaaatta tacaacctaa taaatatagt atcttaatat tgactttaga aaataataca
     9241 cctataaaag gtgatgcaat tgctgaggca atagtaccaa tagtgaatat tagagaaaaa
     9301 gaagctaaac taaagccttc tccttctaca acataactta taaattgagg ctgtatactt
     9361 gctacaatac taaatggaac agcttgtatt aacatacaac caagtactat aacccaagca
     9421 tttgaaaagt ttttaatgct aaatttattg tttagtaatg tattcatggt atctctcctt
     9481 taggttatga tttgtagata ttaatctaat tattctaatt ttatatatta gttttggata
     9541 gcctaactat ttaaatgtaa tttgggtatt aatataaaaa ttaactataa aaattgatta
     9601 ttttaaatgt atggggtaaa ttaaagtata taaataaatg aaaggatgga taaaatgtca
     9661 tttgaaaaaa taaataataa taacctagat aaaatacaca ataggaagtg tattatgctt
     9721 gtaaacttta ataaaaaaga attatcatta attaaaaacg taagtaactt tgctggaata
     9781 agagaccata taatcttaag tgaaaaaaac ggagagaata taataagaga cattttagat
     9841 ggaaatatat caagtgaatg tgaaaatggg attaagagta agtctgtaat atttaataac
     9901 actccaagca cacaagtaaa tgcattttta gaaggtctaa aaaaagtgag aataaataga
     9961 ccttttacag ctatggtaac agagacatct attgattgga cattgaataa tttaatagaa
    10021 aatttagttc aagaacgtaa tgctatgtct ttaggaaaaa caattgaaca taagtaaatt
    10081 taagatatct tatagtaatt ttaactaatg tacattgagt atcatattat attttagaat
    10141 ataaaatttt aaatgtgggt agatagagga gatttgagat gaaagtttta tttacaataa
    10201 attatggaaa agaaaaattt gataaaataa gagaattagg ctatgatgtc atacattact
    10261 ctgaagatag tattgaaaat aatgaggatg taaatacagc agatgtacta gttacataca
    10321 atccatttga gagattagat atttctaaga tgaaaaattt acaatatata cagacaacta
    10381 gtgtaggtat agaccaactt ccaaaagaag aggtattgaa gagaaatatt aagatagcta
    10441 ataatagagg cggatatagt gtacctattg gtgaaagtat tgtattgtat attttagaaa
    10501 tatataaaaa tagtgcaaaa ttttttaaac aacaacaaaa taaagaatgg aagatggatt
    10561 tttctgtatc agaattgtat ggacaaagag ttggattttt aggaacaggt actatatctt
    10621 cagaagcagc aaaacgatta aaagcttttg gtgtagaaat atggggtgtc aatactgatg
    10681 gaagtagtaa aaaatacttt gataagtgtt ttgctactga agatatgaat attgtatttg
    10741 aagaatgtga tatagtagtt gtagcaatgc cttctacaaa aagtacagat ggaatagtaa
    10801 acaaagatat gtttaaactt atgaaagatg gttctgtatt tataaatgta ggtagaggaa
    10861 atacagttaa tcagaaagat ttagaagaat gtgtagagaa atttagaggg gtagcactag
    10921 acgtatttga aagtgaacct ttaaacaagg acaataagtt gtgggagtgc gaaaatgtca
    10981 tagtaactcc tcataattct tgggtgtcag ataaaaacaa agagagaaca tttaatatgg
    11041 tttataataa tttgaaacac tatataatgg agaataaacc tgtagataat gttgtagaca
    11101 tatcaagagg ctattaaaaa taaaaaattt tgataaaaat aaaaactctt attagtcgta
    11161 ttaaagatac taataagagt tttttttgta ataaatttaa agtcaaaaaa gtgatatact
    11221 aaaaaatata taaataggag ataattaatt atagggaaat ttcaaaataa tttaatttta
    11281 aaaatatgaa gaggtgcaaa aagtgagcgt aaaagatgaa attaataaac ttatagagac
    11341 aataaactac cataatgaaa ggtattataa tcaagatagc ccagaaatat cagattatga
    11401 atacgataag ttaatgaagg agttaatttc tttagaagaa gaacatccag aactaaagag
    11461 aattgattct ccaacaaata gggtaggagg taagccatta gataaattca atcaaattgt
    11521 acataaaact cctatgttga gtttatcaaa tgctttttca gagcaagatt tgagagattt
    11581 tgataagaga gttcaagaat atgtgggaga aaatgttgaa tatgttgttg aatttaaaat
    11641 agatggtctt tctgtaggtc taacttataa caatggagag tttgaaaaag gagcaactag
    11701 aggagatgga gttgtaggag aagatatttc tcaaaactta atgacagtaa aaagcatacc
    11761 tcttaagata aatgataaaa aagaactaat agttagagga gaagtatata tatcaaaaga
    11821 taattttaga aaagtaaatg aacaacaaga agaacaagaa cagccattat ttgctaatcc
    11881 aaggaatctt gcagctggtt cattgagaca attagaccca aaactaacag caaagagacc
    11941 attagatata tttgtattta atatggaaaa tatagaagaa tatgatttag aaagtcacag
    12001 tgaatcacta gagtacttag aaaaactagg attttcagta agtcagagtt ataaagtttg
    12061 taaaagtata gatgaagtta ttgagcatat tgaatactgg acagataaca ggggtaattt
    12121 agactacgaa atagatggta tggtaataaa agtaaacaat ataaaacaaa gagacgaaat
    12181 gggatataca gccaaaagtc ctagatgggc aattgcatat aaattcccag cagaaaagaa
    12241 gaaaactaaa atagtagata taatagtaga agttgggaga actggtacaa taacaccttc
    12301 agcaattctt gaaccagtca gacttgcagg tactactgta agtagagcta cacttcacaa
    12361 tgaagattat ataagagaaa aagatataaa aataaatgat acagtattag ttcaaaaagc
    12421 aggggacata atacctcaag ttttagaagt tataaaagag gaacgtactg gagatgaaat
    12481 agattttaaa atgccagaaa agtgtccagt ttgttcagag ccaacaataa gattagaagg
    12541 agaggctgct gtaaaatgta tcaatatgtc ttgcccagcc caaataagaa ggggaattat
    12601 acactttgtg tcaagggatg caatgaatat agatggattg ggagaatcta taattacact
    12661 gctattaaat gaaaaaatta ttcaagatgt atctgattta tattatataa aaaaggaaga
    12721 tgtagtcgac ctagagagaa tgggcgaaaa atctgctgac aatttaataa attcaattga
    12781 aaaatcaaaa gaaaatgatt tatggagact tataaatgga ttaggtatta aatttatagg
    12841 agttaaagca gctaagatac ttgcatataa ctttaaggat ttagatgaag taatttctgc
    12901 aactagtgag caactagaag aattagagga atttggaagt ataatggcaa acagcgttgt
    12961 cgagtttttt aaggaagaca aaaatatgaa cgttataaac aagttaaaaa atgtaggagt
    13021 aaatacaaaa tcattggata atacaggtga aaaagtagaa aaaatatttg aagggatgaa
    13081 aatcgtattg actggtacac ttcctacatt aaaaagaaat gatgcgaaag atatgataga
    13141 aaaaagaggt ggaaaagcta catctagtgt tagtaaatcg acaacatttg ttttggcagg
    13201 tgaagaagct ggttctaaac ttactaaagc aaatgattta ggaattaaag ttatagatga
    13261 agagagattt ttagaattat taaagttatc atcgaaagat gaagtaaaag ctgtattaga
    13321 gagttaaaaa gtcgcttaat ttagtagaaa actactataa ttaatgatag aatagttcag
    13381 taagctaata agattacgaa aaatgacaat aattaatatt tgacaaaatt aaaaattata
    13441 aaaataaatt tataaaaaat aaaaaatatg agaaaggata taaaaaatga ccagaagtta
    13501 tgatagaagt aacgaacaga taagacctgt aaagataact agagattata caaagtatgc
    13561 agaaggttct gttcttatag aaatgggaga gacaaaggtt atatgcactg catcagtgga
    13621 agaaaaagtt cctccttttt taagaaatag tggtactgga tggataaatg ctgaatattc
    13681 tatgctacca agagcaacac aacaaagaaa gataagagat gcatctaggg gaaaaattga
    13741 tggaagaaca caagaaatac agaggttaat aggaagagca ataaggtctg ttgtagactt
    13801 gaataaatta ggagaaagaa ctatttgggt agattgtgat gtgattcagg cagatggtgg
    13861 aactagaact gcatctataa caggggcatt tgtagcagtt gcagaagcaa tatataaatt
    13921 atataaagca aagacaataa aagagatgcc aataacaaat tttgtatctg caattagtgt
    13981 tggtattgta aatggaatac acatgctaga tttatgttat gaagaagatt ctaaagcaca
    14041 ggtagatatg aatataataa tgactgataa gtgtgagttt gtagaagtac aggggacagg
    14101 agaagagaaa cctttttcaa gagcagattt aaatttattg ttagagttag gcgaaaaagg
    14161 gaataaagaa ttaataaggc ttcaaagaga agctttaggt gaaatagcag atgagatatt
    14221 gggtatggat tatggtaatg aagtagtgat tgctactaat aatgctcata agctagaaga
    14281 aataggtgaa atcttaaaag attttgaata taaagtgtac tctttaaaag atgttgattt
    14341 agcaggtata gagatagtag aagatggaaa aacatttgag cataatgcgt tgataaaagc
    14401 tagagcaata gcaaaaaaga ctaaacttat agcaatatca gatgattctg gcttagaagt
    14461 agatgcttta ggcaaaaaac ctggtgttta ttcagctaga tatgcaggag aacatgcaac
    14521 agatgaagaa aatagaaaaa aactgttaaa agctatgcaa aatgtaccaa tgagcaaaag
    14581 aaatgcaaga ttcgtctctg caatagcagt agtttttcct gatggaaaag aatttgtagt
    14641 aagaggaatt tgtgaaggaa tgataggatt tgaagaaaaa ggtaaaaatg gttttggata
    14701 tgatagctta tttatagtaa aaggatatga taagactttt ggtgaaatac ctagtgttat
    14761 aaaaaattca atcagtcata gagcaaacgc actaaaactt atgaaacaag agtttataaa
    14821 aagggtagtg aagtaatgaa aataggcata gtaagcgaca cacatatgat gattaaaaat
    14881 atggaaaaaa caataccata tttgaaagaa tgtgacctaa taattcatgc aggagataac
    14941 tttactgatt caagatatat tcatagcatg actaatgtag gtattattgc agttaaaggt
    15001 aattgtgact ttgatgctgt tgaggaagaa gttgtctttg aagtggcaaa taaaaccata
    15061 ttcttatgcc atggagataa gtatggtgta aaatatggaa ctaatatgtt agaaaaaaag
    15121 gcaactgaag ttgatgctga tatagttata tttggccata cccatacccc atttagagaa
    15181 attaaagatg gtgtacttta cataaatcct ggaagcactt cacttccaag aggagtatcg
    15241 tataaaagtt ttgtcattat ggatatagaa gaagatgaca taaaaattga agaaatacgc
    15301 atataaaggt gtatttatct aaaaaaatgg caaaaaacgc tcaaaaaatt aaattttatc
    15361 aaataagtac aacgatatta atggaacact tgtaaataaa aaaacttatg tgatataatt
    15421 aagtggttga attataaata gaatgaatta taataccgtt atcgggtatt acataaatat
    15481 cactaggagg attagaagga tgaaagcaga actaattaaa aaagagggta ataaagttac
    15541 tttaaaaata acagtagata acaataaatt tgaagcagca gtaaataagg cttataataa
    15601 aagcagaaat aaatacaata tacctggatt tagaaaaggt aaagctccaa gaattgttat
    15661 agagactcaa tatggaaaag gtatattcta caatgatgct atagaaatat tattcccaga
    15721 agtttatcca gaagctatca aggaattaga catagaccca atagacaatc cagatttaga
    15781 tatagaagaa ataagtaaag ataatgggtt ggttatggtt cttaatgtag aagttaaacc
    15841 agagtttgaa ttaggaaact acaagggtat agaaatagct aaggttgaga atactgtaag
    15901 tgacgaaaat gttgatgcta aactacaaga aatggttgaa aaaaatgcca gattagtaag
    15961 tgtagaagac aaagctttag aagatggaga tacagctata atagacttcg aaggttttga
    16021 aaatggtgta gcttttgatg gtggtaaagg tgaaaattat aacttagtta taggttcaaa
    16081 cacatttata ccaggatttg aagaacaatt agtaggtaaa aaagctggtg aagaagtaga
    16141 agttaatgtt actttcccag aagaatatca ctcacaagat ttagctggaa aaccagttgt
    16201 atttaatgta aaaataaatg atgtaaaagt aaaagaatta tctgcacttg atgatgaatt
    16261 tgctaaagat actagtgaat ttgattcttt agatgaatta aaagcagatg taagagctaa
    16321 gttagaagaa gaagctaaaa atagagcaga tgcagaaact agaaattcag tagtagaaaa
    16381 agttgctgaa aatacagaaa tagaaatacc agaagttatg atacaacatc aaatagataa
    16441 tatgttaaat gaacttaact accaattaca atatcaagga tttggattac aacaattact
    16501 agagatgact ggtagaacta tggaagaatt aagagaagag agaaaagaag atgctaaaaa
    16561 attagttaag tcttctttag tattagaagc aataactaaa gctgaaggaa ttgaagcaac
    16621 agaagaagaa tttaaggctg agttagaaaa aatggcttct gcttacaata tggaagtaga
    16681 aaaaatagaa gcttctttaa gagatgctga caaagaagat ataaaaggtc aaataaaaat
    16741 aagaaaaaca atagatttat tagttgataa tgcaacaata gcttaataaa ataaacgcta
    16801 actaatatag ttgacgttat gaaatgttta gtatataatg atgtgcaaat ataatttagt
    16861 taaatgcgta taataattta cagtagctta aaaaagctac tgtaaattat atagaataaa
    16921 gggggtatga aaccatggca ttagtacctg tagttgttga acaaacagga agaggagaaa
    16981 gatcttatga tattttttct agactattaa aagacagaat aatcttctta ggagatcaag
    17041 ttaacgatgc cacagcaggg cttatagtag cacagctatt atttttagaa gctgaagacc
    17101 cagacaaaga tatacattta tatataaatt ctccaggagg aagtataact tctggaatgg
    17161 ctatatatga tactatgcaa tacatcaaac cagatgtaag tactatatgt ataggtatgg
    17221 ctgcttctat gggagcattc ttgttggcag caggagcaaa aggaaaaaga ctagcactac
    17281 caaatagtga aataatgata catcaaccat taggtggagc tcaaggtcaa gcaacagata
    17341 tagaaattca tgcaaagaga attttaaaaa taaaagaaac tttaaatgag atattatctg
    17401 aaagaactgg tcagccatta gaaaaaatta aaatggatac tgaacgtgat aacttcatga
    17461 gtgcactaga agccaaagaa tatggtttaa tagatgaagt atttacaaag agaccgtaga
    17521 tagagagagg tgttaatatg tctaaatatg aagaaaaacg acaattaaag tgttcattct
    17581 gcggtaaaaa tcaagatcaa gtaagaagat taattgcagg tccaaatgta tatatttgtg
    17641 acgagtgtgt tgaactttgt gacgaaatta ttcaggaaga aatagaagat actatagatg
    17701 aagatactac atctttacca aaaccaaagg aaatgatgga gattctaaat gattatgtaa
    17761 taggtcaaga aaaagctaaa aaagctttat cagttgcggt ttataatcat tataagagaa
    17821 tatacagtaa aaaatctagt agtaaggata tagaaattca aaagagtaat atacttttat
    17881 taggacctac aggttctgga aagacattac ttgctcaaac tctagcaaga actctaaatg
    17941 taccttttgc aatggcagat gctacatcat tgactgaagc tggatatgtt ggagaagacg
    18001 ttgaaaatat acttttaaaa cttattcaag ctgctgattt tgatatagaa aaagctgaaa
    18061 gaggtataat atatatagat gagatagata agattgcaag aaaatctgaa aacccatcta
    18121 taactagaga tgttagtggt gaaggtgttc aacaagcact tctaaaaata ttagaaggta
    18181 ctgttgcaaa tgttccacca caaggaggaa gaaaacatcc ccatcaagaa tttttaaaga
    18241 tagatactac taatgtatta tttatattag gtggagcttt tgatggatta gagaagataa
    18301 ttcaaaaacg tggtggagat aaaacactag gttttggagc taaaatagaa agtaaaaaag
    18361 aattagattt agggaagctg tatgaaaaag tacttccaga ggatttatta aaatatggta
    18421 taataccaga gtttatagga agaataccag ttttagctac tttagagttg ttggatgaag
    18481 atgcattaat gcagatatta caggaaccta aaaatgctct agtaaaacag tataaaaagt
    18541 tattggagtt agatgatgtt gagctagaat ttgaagaagg tgctcttcgt gcaatcgcta
    18601 aaaaggctat agaaagaaat acaggagcta gaggacttag aagtatagtt gaaagcgtaa
    18661 tgatggaaac tatgtttgaa gtaccatcta gagataatat aaagaaggtt atagtaacag
    18721 agaaatctgt gaacgaagac tcagtaaatc ctatcatagt acttaaggat caagaggaaa
    18781 gtgcataaga tgatgaaaag gagctttaaa agctcctttt tttatgttaa tatgctaaat
    18841 ataaaatagg tatcattatc ataaaaatgt gagtaatata cctagaatac caaagacgaa
    18901 tacaattgca atggaaccaa tttttccttt atataaaaga taaaatgatg ctataaatgc
    18961 aattattcca tataaatccc aattaacttc tttggcagat gaaaaagctg ctgataatat
    19021 gaatcctaga gtaattggtc taagaactgt caataagttt tctacctttt tattattttt
    19081 aaatttagaa aataactttg atataatagt tagacctatt aatgcaaaaa ttgtaacacc
    19141 aatagttgca gctagagaac caaagaagcc agcagtctta aatcctacaa atgtagcact
    19201 atttattgct acaggacctg gtgtagattg tgatatagca agtaaatcca aaaactcttg
    19261 attagttata aagtgatatt tagatataaa ttcttgctgg ataaatggta gcatggcata
    19321 accgccacca aaactaaatg cccctatttt aaggaatatt aagaagagta gtattatttc
    19381 tgacatagac tatatacacc tcctccaatt attaaataaa tagggcttat attgaataca
    19441 ccaacagata aaactgctat aattaatagt agtatgttag ttttagactt tggtagtttc
    19501 ttgaacatgc tcgtaaaaga atacaatata agagctatta caacaggcgc aactccttta
    19561 aaaaatccat ctaaaatttt agatgatgaa tttttaaagt atagatacga taagactaag
    19621 actatacaaa atgatggtaa agcagagcct aaggtacata taagaactcc tggtatacca
    19681 taaagtttat atcctaataa tacagatata ttaactgcca gtactccagg ataactttga
    19741 gctatggata aataatcaat aaattcttcc tgctctaaaa gtttttgttt gtttacaagt
    19801 tcatcttgta taagaggaac catagcgtat ccaccaccaa atgtaaacgc accaattttt
    19861 aaaaaggtta aaaacaattt caacataata gaaacctcca aaagataaat aacatctaag
    19921 tatactaata ttaatattat atcataataa aaagataata tagtatgata gtattctaag
    19981 aatttatcat taatgttgaa aattaacttg ttcaaatata taatattaaa agcaaagcaa
    20041 ttagactaga aaaggagtaa tgttgatgga acaaaattat actaaaatag atcatgaatt
    20101 accattaatt cctctaagag gattagctat atttccatat atgatattaa attttgatat
    20161 aggtagagag atatctctta aagctttaga ccaagctatg atggatgaag aacttatatt
    20221 tttaacttct cagaaagaag cagaggtaga tgagccagga gaagaggatt tttatcatgt
    20281 gggaacaatc tgtaaagtta agcaaatgat aaaattacca ggagatacag ttcgtgtttt
    20341 ggttgaaggt gtatcaaggg gtagagtaaa gaaaatagaa caagaagatg ggtatttcag
    20401 agcagtaata gaagaaatag tatttaatag tgataatttg gatagtgaaa cagaagttga
    20461 aattgaagca tttgtaagaa atgtatttga tgcctttgaa gagtatataa atattggaaa
    20521 tagggtatca ccagaaatat taatatctct agctgatata gaagatgtag atagatttat
    20581 agatacgata gctgcaaaca tatatctaaa atcaagccaa aaacaagaaa tattagaaga
    20641 atttgatatt agaaaaagac ttgaacttat ttattctata ttattagagg aaatagatat
    20701 attaaaaata gaaaagaaaa taactttaag agtaaaaaaa cagatgaata aggttcaaaa
    20761 agaatattat cttagagaac aattaaaagc tatacagaaa gaattaggtg aagaagaaga
    20821 tataaattct gaagcagatg agtatagaga aaagcttaaa aaaataaaag cacctaagac
    20881 aaccaaagaa aaaatagaaa aagagataga taaattttca aaaatatctt ctatgtctcc
    20941 agatgtatct gtaagtagaa actatttaga tactatattc tcattgccat ggaataaaga
    21001 gacaaaagat aaattagata taactaaggc aaaagatata ttagatgaag accattatgg
    21061 attagaaaaa gttaaggaga gaatactaga gtatctagct ataagaactc ttgctaagtc
    21121 acttaaaggg cctataatat gtctagttgg tcctccagga acaggaaaga catctatagt
    21181 aaaatcaatc gccagagcat taaatagaaa atttgtaaga atatctttgg gtggagttag
    21241 agatgaagca gaaataagag gtcatagaag aacttatgta ggttcaattc caggaagaat
    21301 aattaatggg gtaaaagaag cccaaacaaa aaatcctgta ttcttatttg atgagataga
    21361 taagatggca gcagattata aaggtgaccc agcttcagca atgttagaag tattagaccc
    21421 agagcaaaat aaggactttg tggaccatta cttagaaata ccttttgatt tatcaaaaat
    21481 actatttgtt acaacagcaa atagtctagg taatatacca agaccattat tagatagaat
    21541 ggaagtaata gaagtatctg ggtatataga agaagaaaaa ttaaatatag caagaaaata
    21601 cctacttcca aaacagatta aagaacatgc tttaaaagaa aactttataa aaatagatga
    21661 tgaaacttta agaagtataa ttaaccatta tacaagagaa gctggtgtaa gaacactaga
    21721 aagaactatt ggtaagattt gtagaaaggt tgccaaaaaa tacgttgaag acccaactct
    21781 tgaagaggtt gttataaata agtctgacct agagacatat cttggaaaag acatgtttaa
    21841 gtatcaactt gcagaagtta atcctcaaat aggattagta aatggtcttg catggacagc
    21901 agttggtgga gttacacttg aagtagaagt aaacgtactt aaaggtaaag gagaaattgt
    21961 attaactgga aaattaggag atgttatgaa ggaatctgcg aagacaggta tctcttatat
    22021 aaggtcaata gtggacaagt ttgatataga ccctgaattt tataagacga atgatattca
    22081 tatacacatt ccagaaggcg ctgttccaaa agatggacca tcagctggta taactatggc
    22141 tcttgcagta atctcagcac ttactaaaag acctgttcct ggaaatatag caatgacagg
    22201 agagataact ttaagaggta gagtcttagc agtaggaggg gttaaagaaa agttattagc
    22261 agctcataga gctggtataa caaaagtatt aattcctaaa gaatgtgaag ctgatttaga
    22321 tgaaatacca gaaaatgtaa aagaaaaaat ggagtttgtg cttgtagaac atatggatga
    22381 agtattagaa caagctttat taaagagtgg tgaaaataat gaaaattaga agttcagaga
    22441 taactatgag tgctgtgaat aaatcacagt atccagcaga aggaatccca gagatagcat
    22501 tggctggtag gtcaaatgtt ggaaaatcat caataataaa tacattgctt aacagaagaa
    22561 acttcgctag aaccagtcaa acaccaggaa aaactagaac tataaatttt tatctaataa
    22621 ataatgaatt ttattttgta gaccttccag gctatggata tgcaaagata gctaagtctg
    22681 aaaaagaaaa gtggggaggt ataatggaaa gatatctaga aagtagacaa gagttatgtt
    22741 ctatattcct acttgtagat attagacatg agcctacagc agatgataag cttatgtatg
    22801 aatggataaa gcactttgga tataactgtg tagttattgc aactaaggca gataaaatat
    22861 ctagaggaca atatcaaaaa cacataagta taataagaaa aaaattgcaa atggaaagta
    22921 gtgaaaaagt aattcctgtt tcttcactaa aaaagactgg tgttgaagaa ttatgggaag
    22981 agattgtaaa tcaatacaat caacatggat atgaaataac agtagattaa atttaaaatg
    23041 ttaaatattg acataagatt tatttgaata ataaatgtaa taatagttag ttttaattat
    23101 attaatatta aagcaaaata taggatgcct taaaatagtt ttaatgaact ttttttggca
    23161 tccttattgt ttataaacaa taaatatcag taattttgct aaatactaat aaattttagt
    23221 aaggtatggg aaaattagta taaattagtt caactaaaaa attattgact tatgtagtca
    23281 gcaataaata gcatttaaga aatagattta tctgtttttc tcataaagaa aacagttagt
    23341 ataagcccta taaaacatac tgatgctgca atccaataag actgattgct agctataaca
    23401 taggctgatg tgtgactttt aaacttttga ttgtatgtaa gactttgtgc aaaaaaacta
    23461 ctaaaaaatg ctgttccaag agcaaatgat aaattacgaa tagttgcaag aaaactgcct
    23521 ccgtacccct gtttttgagg aggaacatct gctaaaatac tactattgtt tggtgaacta
    23581 aatgctccta gcccaagtcc aaaaataact aaacatacaa ttaaaagata caatggagaa
    23641 tctgctttta aaagtgccat tccaactagt gagatggtca taaatgaaaa agatgctgtt
    23701 agaatgtttt ttgcaccgtg tttatcagaa agtgaacctg caataggtgc tataagtacc
    23761 ataataagtg gatgtacagt cattacataa ccagccatca taggagataa attttttaat
    23821 tgttctaaat aaaatggaag tagaaaagat actgccattt gaggaaaata acaagctact
    23881 ccaatgatat tgcctacagt aaagtttcta tttttaaata gaggtaggtc aataaagctt
    23941 tgttcaaatt ttacttctct taatgccaac aataagaaga ttataagtgc tgttatacct
    24001 aaatacaatc ttgtattacc cttctcattc attgcaagta atataagcgt agtgcaagat
    24061 gcgaaaagta gaagacctga aatatcaaag ctcttgtttt gttcatccaa aacaggttta
    24121 ggcagaaatt taatgccaag aaagactgct ataataccaa taggtatatt gataataaaa
    24181 atagaaggcc atccaaaatg ttctaaaatt atacctccaa ttacaggacc actcatattt
    24241 cctataccaa ctacagctcc agtgattcct atagcttttc ctttttcatt tgctggaaat
    24301 gcattggaaa ctataccaag cccagtagcc attaaaatac ttgctccaac tgcctgaaag
    24361 attcttgaag aaattaatgt tgataaattg tttgacatac tacacagaaa agaacctatt
    24421 gtaaatataa aaaatcctaa tgcgtataga cgatttgaac ctactttatc accaagtttt
    24481 ccgaaaaata acatagtagc tgttacaaca agcatataag ctgttacaac ccactgaatt
    24541 tgtgacatgt taattttaaa gtcagcagca attgtaggat ttgcgatatt tagtatactt
    24601 ccatcaagag tagacataaa tacaccaata cagatgataa tcaatactat ccatttttgt
    24661 ttcatgataa cactccaatc ttaatagatt ttataagtac gatataattg taaaataaac
    24721 aacaaaaaaa gcacctgtat attaggtacc ttgaatgtgt ctaatttcat gaataaatac
    24781 ggtagttgaa ggatttgtat agattactca tgtaaaatta cataaaggta ctcatatact
    24841 attttcttct accatccaga ttttactgtc ggctttggaa tatgaccaaa ttatgccata
    24901 aggctcgcgg gcttttaccg ccgataggga atttcacccg tttatgaaga aaaacagatg
    24961 tattttgtaa tattatttta acataaaatt ataatggaaa caattggatt taagtaatat
    25021 ccagctgtat tacaatacaa atatttcaat atggacactt aaattgtatt tatagataga
    25081 ataaggtaca gtatgagaat ctataataat tagataaaat taatatgtta ttagtattag
    25141 atggtaagtt ttaaatttgt caaaatcaga aagctgtaat aaaattctta taatatgaat
    25201 atcttaatta agagatattg taaattatga ggaggcgcta atatggaagg aaaggtaaag
    25261 aaggcattcc caggtggaaa tacatcacaa ggctcatatt ctttttttga ctatataatt
    25321 cctgaaaatg taaaaagagt tttttgttta aagggtggac ctggagtagg aaaatcctca
    25381 cttatgaaaa aaatttataa agagtttttg catagaggat atgatattga tttatatcat
    25441 tgtccttctg acccaagttc gttggatggt ttagttataa agaaattagg cgtggtactt
    25501 atggatgcaa ctgccccaca tactatggac ccaaagctac ctggagcttt ggatgagata
    25561 attaatttag gtgattactg gaatacagaa gaattagaaa agaataaaca agaaatatca
    25621 gtttatgata aagatattag taattcattt aaaagagcat ttaagttttt aaagtcagca
    25681 gaaccaattt ttagagacat agaagaaaaa tattctgatt gtatggatta tggcaaagta
    25741 aatttggtca cagaagaatt tataaaaagg ttatttgatg gagttaaaag cacaggaaat
    25801 ctaaaaagag aaaagcattt atttggttca gctataactc ctgtagggtg tttagattat
    25861 acagaaaaca ttttaaaaga tgtaaagaaa gtctattatt tagatggaga aataggaact
    25921 gggaaaacta cattattaaa caaagtatat aagaaagcta ctgaaaaagg tttaaatgta
    25981 gaagtttatc attatccact tattccagag aaaattgaaa ctgtactatt aactgattta
    26041 gatataggca taactataag tacgactttt aaagaagaag atacaattga tttaaatcag
    26101 tttttaaata gagaaaaact acttaaatat gaagaagata ttaaatttga tgaaaaagtt
    26161 ttagatgatt taatttgttg ggcagtacta aatcttaaga gagccaagtc taaacatgat
    26221 attatagaaa gttactatag tcctaatatg agatttgatg aagtagggaa attaagagat
    26281 aagttaatta aaagaatttt aaaatatgag gaaaacttat aaacgtatat gtttaaaatt
    26341 aatgttaata ataatataat ttttagtaaa ttggtgtagc tttgaggcta tgccatttta
    26401 cttttttttg ctaaaaaatg atattaataa tctccaaagc cattatttgt ttttcataat
    26461 tattatttcc tttcctaatt tatgtttttt tataatatca caacaatgtt tattgaaagt
    26521 ttatataatt ttaagaacat ctaaaaatgc atacttgata ttggtaaatt agtgatagga
    26581 gttcaatgta tgatattata tactaaagat gaattttaat atataacttt gatataataa
    26641 gcatatgtaa atgtttaata tttaattaaa gaaaattatc atataaaaat aaatttgtaa
    26701 ggagcaatac agtatgaaaa aacaatatgt gtttataata ctagcaagta ctattttagg
    26761 tatacttgtt ggaaccatat ttagagatta tagcaatgaa gaaacagttt atacaagcaa
    26821 agacaagtca ataagaaaag aaataaaaat gacaagaaaa tctataaaag aattaaccaa
    26881 agagaaagac aagttagata aagaaattaa ttcaatgaaa caaaatcaaa aaaattctga
    26941 agaaatatca gaaatagaaa cacttagaga tagtctatca tattcagatg taaagggtag
    27001 tgggataata ttaagtatag atgctataga tgaaaaaaca gggaatatag ctaatagtat
    27061 agactataat aagattcttg taaaagttat aaatgaatta aaagtaaacg gaggaaaata
    27121 catagaaata aatggtcaaa gaattaatca atattcagaa gttgtacttg caggaagcca
    27181 tataaatata aatggagttc ctgtagcaca accatatgaa ataaagtgca ttggagataa
    27241 ggagaaatta tctaattatg tagataaagg tagtaaatat ttagatagca tacaaaccaa
    27301 ttatccaatg aaaataagca taaaaactga agaaaatatc tctatgaaaa aaatgaatat
    27361 acctaataaa ttaaagtata taaagggtga ttaatattat attagaggaa agcagtttgc
    27421 caatgttaat accagaaaaa cttgcaaaga aatataatgt atttccagtt gagtttcaag
    27481 atgataattt agttgtagaa atagaagatg aggatattta tgctctacag gacttgagat
    27541 tagctacagg taaagaaatt atattgaaga aggagaaaaa agaacttata agtgaaaaga
    27601 ttgaaaaata ttataatagc tttgaacttg atgaggatta tgcaaaaaaa ttatttgaaa
    27661 atcttttaga aaaagctata aaagaaaatg caagtgatat acatatagaa ccatttaaag
    27721 aacatttaat agtgagaatg agggtagatg gagaactaaa ggaagtatca aagtttttag
    27781 ttgatgtcta tccatcattg tctacggtta taaaattaaa ggcatcaatg gatataacag
    27841 aaaaaaggct tcctcaggat ggtagggtgg atataaagtt aggtggaaat ttaattgaca
    27901 ttagagtttc atcaatacca actgtctatg gtgaaaaaat agttttgagg atacttaata
    27961 gagatacttt tttaaaagac aaattagaac ttggtttttc agaggaagct ataaaatcta
    28021 taaatcgtat aataaataaa agagcaggag tattattagt gacaggtcct acaggtagtg
    28081 gaaagactac aacagtatat tccttattaa atgatttaaa aggaataaat aaaaatatta
    28141 tgactataga aaatcctgta gagtataaga tggatggcat aagtcagatt caagtaaatt
    28201 caaaagtagg gttgagcttt gatgtaggtc ttagagcgat attaagacaa gacccagata
    28261 taataatggt cggagaaata agagatgcag aaacagctaa gatagcagta agagcagcta
    28321 taacaggtca tttagttata agtactttac atactaatga tgcagtatct tccatagcta
    28381 gattactaga aatgcaaata ccaccatatc ttttaaatgc ctctcttata ggtgttatat
    28441 ctcaaaagtt ggttagaaaa gtttgtaatc attgtagcca tgagattatg ataaaagata
    28501 attttagtgg agatgtaaat actaaggtag ctgtagggtg tgaaaaatgt aatgataaag
    28561 gatactttgg aagaacagca atttatgaaa tcttagaaat taatgatgat ataaagacat
    28621 gtataagaaa tatggaggat tctagtacta ttaaagatgt ggcacaaaat aatggaatga
    28681 taacatttga agatagctgt aaaagactaa taaatgaaaa aataacgaca ttagaagagt
    28741 gtttagtagt aaatgaaatg atttaactga attgtatagt taaacttcgt ttggtcagtt
    28801 gtctttattt aatctatttt aattaagatg tttgagtata aattatattt aagtgaaata
    28861 aaattaaatg cattaaatta gaaaatatta agtttattta attgtaatta atataatttg
    28921 gaaggtatta tagtacatga gattatctaa aaatatattt tataatttag aaaagtttta
    28981 tttagtatta aatagaatca gtgataaaga aattagagta atttgcaaag agataggcat
    29041 attgctggaa tctggatgtg aaattacaaa aatatttgaa atcattgaga gtcagtcaag
    29101 taaaaaagta aagaatttgc ttagtatagt atcaaatcat attcaaaaag gtaactcaat
    29161 agcagaatca tttcaaataa caggtatatt ttctaaattc tttataagta tgataaaagc
    29221 aggagaaact agtggaaact tagatataat aatgagtgat ttatctaatt attatgataa
    29281 agaatacaaa ttaaaaatga aaataataac tatttcaata tatccaataa tacttataat
    29341 attatctatc ttatcaatgt tgtttatatt cgtatttgta atacctaatt ttcaggtggt
    29401 ttttaccaac aatggaattg aaccaccttt aataactaga gttttaatgg gaatatctac
    29461 agtggttaca aataacttag cttatataat atttagtttt atattgtttt caataggaag
    29521 catttatttc tttataacaa atgataatat aaaaaaattg attaattcgt taaaattcaa
    29581 aatacctttt ataaaaaaaa ttaatcagtt agtagctaca acaagatttt caagggcatt
    29641 gtccgtttta attagcagtg gaatacaaat tgtggaagct atagacatgt cagctagtgt
    29701 tatagacaac gaatttattt atgaaaggtt aaagatttct aataattata taaaaaaagg
    29761 aaatagcata ggtaaatctt tgaatttagc aaatgttttt ccaaaattat ttatttcaat
    29821 ggcaaataca ggagaagaaa gtgggaaact agataaaagt ctaaatgtaa taaataaatt
    29881 ttatgaaaat gaattaaata acaaaataga gcaaataatg aaatttatag aacctatgct
    29941 aattgtattt atgggattaa ttattggcac ttttatttta gcaatggttg ttcctatgtt
    30001 tgatgcaatt actaattttt agagagaaaa ataaatttta ttagatgaaa cttttgaaaa
    30061 ggagagaata tttaattgat aaatttgata aataaaaaac gaaaaggatt tacacttgtt
    30121 gaaatgattg tagtagtaac tattttaggc gttatatcta gtatagcatt agttaagtat
    30181 agtaaggttc aagaaagtgc caaattaaat gcagactata cgaatgctgc taatatagta
    30241 actgcagcta gcatggcaat taatgatgat gaaaagacaa tagactctct aagtgtagaa
    30301 acattgaagg aaaagggata cctaaatact gttccagttc ctcagagtac atcaggtaaa
    30361 ttcgaacttg tcataaatga tagcggaaca gatataagcg taaatataaa ttctaaacaa
    30421 ttttatccaa aataatattt tatattgatt gctgtaagtt ttaaaattat ttttatttaa
    30481 gaaggagatg gctataatta aaaaaattct aaacttagaa ataaatgatg attatataag
    30541 gcttgtattt ttaagaaaaa gtcataaaaa agtttttata gataaatcaa ttataaaaga
    30601 gattaacttt gatataaaaa atgatagtaa ttcgattgag aagattaaat atatagaaga
    30661 tgtagttaga tttgtaaaag aggagattgg taaatcaaaa atattatata aaaatttata
    30721 ctttaacatt caaattcaag atatagtcat tagaaatgtt gaagttctaa atactaagaa
    30781 aaaaagagac atattaagca tgattgaatt tgaaataaca caatacattc caataaacat
    30841 aaataactat tcaataaaat ataaagttat aaattctaaa aatgataaat tgaatataca
    30901 agtaattctt ttcccaaaga gtattattca attaattaag aacatttcag aaaatctaaa
    30961 tatgaatcca aagactataa atataaattt tgatatatta caaaagctta taaacttaaa
    31021 tttaatagag aatttttcag aagaaggggt atttatagaa tgtaaaaaaa gtcagttaat
    31081 tataaatata acaaaagata aaaaaataag agaaacatac ttgctatcaa aagagggaaa
    31141 atcatatgag ttcataaaaa gattattaag ggattttaag tatgtttatt actatggtat
    31201 agaaaattgt tttattgaag aatactttaa atatacagat aaatctattg aagtaaatcc
    31261 attaagatta aaagataaag taaaagtaga aaataatttt gatgcagatt tagaagacaa
    31321 taggataaat tatataaata gtataggaat gattatttaa gtgaaagtgg ataaaacaat
    31381 aaattttctt aatggattta aaaaaactaa accatgtaat aaaatctata aaataataat
    31441 agtcttaatt ttaacgtgta ttttatttaa atcatttatg tatgtgaaat ctataaatga
    31501 acttgaagat tatataaatc aaaataagct agtggataaa tcaaagcaca ctttaccaac
    31561 aacagataaa actagagaga aattttctaa aataaaactt aatgaaataa aaaaaatata
    31621 tgaaacaatt ggaataaata gtattactaa aatatcgata gataaaaata agctagagat
    31681 ggaaggtgtg tgtagtgatt tagatgtttt aaacaaccta aggaaaataa agtacataaa
    31741 atattattac atagacagta ttgtaagaga tggagaatat tatagattta gaataaaaag
    31801 ttagataggt gattattttt gagattaaat aatagagaaa aaaatctact taaaatattg
    31861 ttaatattag ttattatatt ggcaagtgat atagcagtaa gttatttgga agaaaaccta
    31921 actagtttga agaatgaaaa gcaaaatata ataaataaaa taaataatca agataattat
    31981 caaataaagg ataataagca tatagatgat aaatatatag aaagtgttga attaaataaa
    32041 aatgaagaat tgaaaaataa ttttaataac tcatttttag ataaaaaaac aaataaagat
    32101 atagtgttat tagtagaaaa tgaactgaga gatattgtga atgtagaata tattaatcaa
    32161 gaaagtagtt tagataatca caataaaaaa caagttaatt tagaaataaa agttaatgga
    32221 gaacttgcaa atgtgttgaa acttgaaggt gtaatgaaga agttaagact aaataataaa
    32281 cttgaaaaga tagaaattaa caaattaaaa gtcaataatt ttgatgttca aaatattcca
    32341 aatgaatata aacaagaaaa agacaatatt gttgaatgta aaatgacagt tagagtcata
    32401 taacaaaaaa gaatagataa agtaaaaaac tattatcaat taataaaatt ttatagagga
    32461 attagtttta cgataattca tttctacaag agggattgtt gatgatttta tcgaaatcct
    32521 aattaaagtt aatatattgt accaaaatat aagtgaattt aatagaatat ttacttatac
    32581 tatagattga ttaataaaaa aatggtataa taacaaattg tactttaatt taataataag
    32641 ggagtggaag tcatattgtt agggagaaat gagctatgcc cttgtggaag tggcaaaaaa
    32701 tacaagaaat gttgtttaaa taaagatatt gtttcagaaa gagcatgcag aaaaactgaa
    32761 ctttcacaaa aacaatatac agatttatat tcaaagttat atgattattc aagacaggat
    32821 aagtttaaag aagaatgtga aaaagctaaa gaaatgtttt atataatgca aaatgatagt
    32881 gtaaatgaaa aatttgaaag attttttaat acttatttaa tacaagacca cataatggaa
    32941 aataaaaagg ttatgacagt tggttttctt gaagaaaatg gtgcaaacct aagtcaatca
    33001 gaagtatcaa tattaaaaag tatgtttgaa tcatacgtaa gtatttatga ggtaaaagaa
    33061 gtttctgctg gaaaaatagt attaaaggac tgtttaagtg gaaatgaact ttgtacagaa
    33121 gatgtaaaac ttctgagaag ttttaaaatc ggaagttgta tgatagctag aatagttgat
    33181 attgaaggaa ctaacatatt gatagatata actataagta tatcaaatga ggttaaagat
    33241 ataattttaa aggatattat gaatctattc aatcaatatc aagatgtata caaagatatg
    33301 aagtcgttct taatttatca tacacatata ctatacaagt atatacaaca gcttttagac
    33361 ccaagtatag ctgaatattt aaagagagaa agagataaaa acgatacaaa agttaattca
    33421 gaaaatgaat tagctgaaga agaatgtaaa gttttagata ctcttaaaga aaatgtagaa
    33481 aaagaaaata tagatgcatg tatagagttt tggaatgaat ataagaaaaa tcatgaaaat
    33541 ataaaaggag ctgaaaatgg ttgggcagct gctgttgaat actatgttaa aaaagaagca
    33601 ggacaaccta taactcaagt tcaaatatca aagaaatacg atataagctc tagtacacta
    33661 ggaaagagat acaaagattt aaaaatatct taattaatta taaaaagctt taagtcatag
    33721 ataaagaatc tatagtataa tatatgtata atgtttagaa agaggtatta ataatgagtc
    33781 ttagtttagg aaatgcaatt gctgtatcaa cgaactttat aaaatctaac ccagctgtac
    33841 ctgtgtacaa cggagaagaa atatatgcag ttatttatca tatagaaata ggatataata
    33901 atggtgtatc acctgatacc aaacaatata taataataga ctataaagag tttgatttat
    33961 ctatggataa aaaaaatgaa ctaataaatg ttgctaaaga gtactgtaaa tctaaaggta
    34021 ttgtagaaaa cgaaaacctt gaaataaacc ttttagacaa tgaagaagca gagaacttct
    34081 tagaaaaggt gtttaataac atgaaggtta taagaggtct tataactaaa aaaggataaa
    34141 taaatggact atataggaat agaaaatata acaccttatg aaaatacata tgaatttagt
    34201 gtatatgaat atgatgatga aatcacctta ggtagtgaaa agttatatgt gtgtgaatta
    34261 agggttgtat tgattaaagt taattctctg tatgttgaaa gattgcataa atcagttgaa
    34321 gcaatggtct tagtaaaaaa cttgaaaaag gatttagata aaacacttgt tgtaaacaaa
    34381 ataaagaatt ttgtgctaga tgagatttgg gtagaaaatc tagtaaaaga gaatatagaa
    34441 gttatatttg tagaaagcta ggaataaccc tagctttttt atattacaat ctaagagagg
    34501 aaaacaatat gttaagagta tctaatgtaa aacttggaat tgataaagat atatctttat
    34561 taaaagatgt tgtacttaag aagctaaaaa taaaagaaaa aaacttagtc aaatatagta
    34621 tatataaaga atctatagat gctagaaaaa aaggaaaaat ggaatttgtt tattctgtag
    34681 atgtagaagt caaagatgaa aataaaatac ttaactcaaa aataaaagat gtaacaaaaa
    34741 taaaggaaat cagatacata aatgtacctg tgggtgataa aaaattaaag aataatcctt
    34801 tggtaattgg tagtggacca gctggtttat ttgcaggtct gcttttagct caaatgggtt
    34861 atgaaccaat catacttgaa agaggtcttg atgtagacag tagaaccaaa gatataagtg
    34921 atttttggac aactagaaaa ttaaaaaata attcaaacgt tcaatttgga gaaggtggag
    34981 caggaacttt ttcggatggt aaacttacaa ctagaataaa agatatacga tgtagaaaag
    35041 tattagaaga gttagttcag tttggagcac cagatgaaat attatactca cataagccac
    35101 atgttggaac agatatatta aaaaatgtag ttaaaaatat aagaaatgaa ataataagtt
    35161 taggtggtca agttagattt aattcaaaag taacagatat agttgtatca aatgattcta
    35221 tacaatctgt aataataaat gatactgaaa aaatagatac agatacaatt atactagctg
    35281 ttggacatag tgcaagagat acttatgaaa tgttgtattc aagaggtata aaaatagttc
    35341 aaaaaccttt tgcaatagga gctagagttg aacatccaca agatttaata aataaagcac
    35401 agtacaagga tttttataat catcctaggt taggagctgc agattataga cttatagagc
    35461 atgtttcaaa tggaagaaca gcatatactt tttgtatgtg tccaggaggt agtgtcatag
    35521 catctgcatc aaatgatttt gaaatagtta caaatggtat gagtgaacat gcaagagata
    35581 aaataaatgc aaatagtgca tttttagtaa atgtaacgcc agaagatttt aagagtgata
    35641 atccactagc aggtgttcat ttccagcaga agtatgaaaa attagctttt gaattaggtg
    35701 gaaaaaatta caatgcacca gttcagcttg ttggagattt tataaacaat aagacttctt
    35761 tgaatttagg aagtgttgag ccatcatata gaccaggata tacacttaca aatttaagtg
    35821 aatgtttgcc tagcttcgta acagagacta tgagagaagc gtttatatct cttgataaaa
    35881 aattgaatgg gtttgcaatg tatgatgctg ttttgacggg agtagaaact aggtcatcat
    35941 caccaataag aatagtaaga gatgaaaata ctttagaatc agtgagtatt aagaatctat
    36001 atccatgtgg tgaaggcgct ggatatgcag gtggtatagt tacagcagca gttgatggta
    36061 taaaatgtgc agaaaaaata atacaaaaat acaccaataa tacaaaaatt taacataaac
    36121 ttaatgattt tttaatattt aacatgaatt taacattatc actcctataa tttgataaaa
    36181 tacaataggt tataaaattt ttagatacag taatctcttt acaaggagga aataatttga
    36241 acattataat aagtctaatg ggtggattag gtctgttctt atatggtatg aaccttatgg
    36301 gagaaggtct tcaaaaatct gctgggacaa agctaaaaaa gataataaaa ctacttacta
    36361 gtaacctatt tatgggagtt ttggtaggta caggagttac agcagtaata caaagttcaa
    36421 gtgctactac tgtaatggtt gttggtttcg taaatgcagg aataatgact ttaaaacagg
    36481 caataggagt tataatgggt gctaatatag ggactactgt tacagcccaa ttggtatctt
    36541 tcgacttaac tggtatggcc ccagtagcat taggtgtagg tattatactt tatttatttg
    36601 gaaataagcc tagaataaaa aatatagccg aaatacttat aggttttggt atattattta
    36661 caggtatgga ttttatgaag atggcagtgg agccactaag agactatcaa ggatttactg
    36721 acctacttgt tacatttggt agatatccac tacttggatt attattggga tttgggatta
    36781 cagcaataat acaaagttca agtgcatcta tgggtatgtt ggttgcactg gcagcagaag
    36841 gtctagtgcc attatcagca gcactgccaa ttctttatgg ccaaaatatt ggtacatgtg
    36901 taacttcact gttatcaagt attggtgcta acaaaaatgc acgaagagca gctatgatgc
    36961 atctaatctt caatgtttta ggaacggtga tattcttaat attcttgaat aaaccagtag
    37021 taagcatggt tacaagttgg gatccaagca atgttgcaag acaaatagcc aatacacata
    37081 cattgtttaa tataatatct gtattgatac ttttaccatt tacaaatctt attataaaac
    37141 tagctataaa gcttgttcct gatagagcag gtgatataga tgaagatgaa actaaaacta
    37201 ttaaatatat agatgataga atgatagaaa ctccttctat agctcttgca aatacgataa
    37261 aagaagcact tcgtatgggt gagaaggcga aggaaagcct aaatgcatct atggaagcct
    37321 tagtagaaca ttcaactgaa aaaatagcta agacatatag acgagagaga ttaatcaatg
    37381 atttacagaa agctatttta aattacttac ttaaactttc aaaagcacct ttagatgatg
    37441 attcaagaga agttgtggat actttgttta atacagtcaa tgatatagaa agaattggtg
    37501 accacgctaa aaatatagct gaattatcgc aagttgcaat agattcaaat atttctttct
    37561 cagaagaagg acaatctgaa cttgatgtta tgtataatag agttgtttca gcatatactt
    37621 atgcattaga atcaatgaga actgataatg ttgatttagc ttgtaaggtt ataaaaattg
    37681 aagaacaagt tgatataatg gagaaatctt gtagagctaa tcacatgtat agattgaaca
    37741 ataatctatg tagtatagaa aatggagtta tttatttaga cgtaataagt aatttagaga
    37801 gaatatctga ccatgctgtc aatatagcac aacaagttat agcgaagaga ttaggaaatg
    37861 attaaaaata attaatttaa aataatataa aatttaaaat agaggataaa taaaagagaa
    37921 actttaaatg atacgtttag agtttctttt tttgtaaatt tatttgacta aaatttttaa
    37981 atttatacat agttatagta tttagaagaa tcgatttcct gataataaat gatgagatat
    38041 gtatgatttt gtggcaaact tttaaaaaaa acacctatat tttgtgttat aatctcttta
    38101 aaacgaatat gctgaaaaga gggatttaaa tgggaaaaat aaattttgat tatagtaaag
    38161 ctacagagtt tttttgtcaa aacgaaatag atgtcatgca accatatgta gatgttgcgc
    38221 acgacatgtt acataataaa actggtttag gaaatacttt tttaggatgg atagaccttc
    38281 ctaaaaatta tgataaagaa gagtttgaca gaataaaaaa atctgctgag aagataaaat
    38341 cagactcaga tgttcttctg gtaataggta taggaggctc ttatttaggt tcgagagctg
    38401 ctatagatat ggtaagtcat tcttttagga atggacttaa aaaagagcaa agaaaggctc
    38461 cagaagtata ttttgtaggg cataatataa gctcaacata tattatggat ttattagata
    38521 taattgaagg aaaggatatt tctgtaaatg taatatctaa atcaggaact actacagaac
    38581 cagctctggc ttttagaata tttaaagatt acttagagaa aaagtatggt aaggaagaag
    38641 caagaaagag aatttatgca acaacagatg caagtaaagg tgcacttaga cagttagcta
    38701 cagaagaagg atatgagact tttgtaatac cagatgatgt aggtggtcgt ttttctgtat
    38761 tgacagcagt tgggttactt cctattgctg ctgctggact tgatattgat gctatgatga
    38821 aaggcgcaaa tgatgctaga gaagcatttc aaaatcctga cttaaaaagt aatgatagtt
    38881 atagatatgc tgttgctaga acaattttac atagaaaagg aaaagatgta gagttattag
    38941 tgaactatga acctcaacta cattatgtaa gtgagtggtg gaaacagctt tatggagaaa
    39001 gtgaaggaaa agaaaataaa ggtttattcc ctgcttctgt agatttctca acagatttac
    39061 attctatggg tcaatacata caagatggaa aaaggctttt atttgagaca gtacttaatg
    39121 ttgaaaactg taagagaaat ataactataa gttcagagga agtagactta gatggtttaa
    39181 attatttagc aggtaagact gtagattttg taaatcataa agcttttgaa ggaactctat
    39241 tggctcatac agatggaaaa gtacctaatt tagtaataaa tatacctcaa ctagatgagt
    39301 ataattttgg atatttagtt tatttctttg agaaggcttg tggaataagt ggatatttat
    39361 tgggagttaa tccatttgac caaccaggag tagaagctta caagaaaaat atgtttgctt
    39421 tactaggcaa accaggttat gaaaaagaaa aggaagagct agaaaaaaga cttaaataat
    39481 tttaaatagt taaggtttaa ttaagattaa aataatataa tgaaatcatc gaaaaggagt
    39541 ttactcaaaa tagatgattt catttttttt atgaaaaatt gggaaaaata tattttgata
    39601 atttatatta tattaagata gggagtggta tgagatgtca agaagaaaga aagggataag
    39661 tttagtaata ttagttgcta taataagttc aatacttagt agttttctaa caataatttt
    39721 agttaaggac aatttagtaa gcaaatctac aggaagttct acgccgatag ttgtaaatga
    39781 tgatggtaag agtcaaaata tttatcaagc agttgcagaa aaagctacgc catctgttgt
    39841 aggtattaca acaactagtg ttgatactag taatatgttt gcaataccaa ctgaaacaca
    39901 aggtgtagga actggaatca tagttgattc aaatggatat atacttacta attctcatgt
    39961 tatatcagat ggtcaagcta caagtgtaaa tgtattattc aatgatggtt caacaacttc
    40021 aggtaaagta gtatggtttg accaacaact tgatttagct atagttaagg ttgataaaac
    40081 tggactaaca ccagcagaat ttgctgatag tgacaaagta aaagttggag atatatcaat
    40141 agcaataggt aatcctcttg gattagattt tcaaaaaaca gttactcaag ggataataag
    40201 tggattagat agaactatac aaacagaaaa aactaatatg actggtttat tacaaactga
    40261 tgcaagtata aatgcaggaa atagtggagg accattgtta aatcaaaaag gtcaagtaat
    40321 tggtataaac acagcaaaag cttctcaagc agaaggatta ggatttgcaa taccaatcaa
    40381 tacagctaag agtatagttg aagaagtaat caaaaatgga aaatatgaaa aagtaacttt
    40441 aggcataaaa ggtacagatg tatcaaatta tgaagcagca acaggtacaa aattaagtac
    40501 tgataaaggt gtttatgttg cagaagtaat atctggttca tcagcagaaa aagctggagt
    40561 aaaggtaggg gatattataa ctaaagtagg agatacagat ataacaggta tgaatgattt
    40621 aaataaaaag ttgtatactt tctcaaaagg tgctagtaca aaaataacag taaatagagg
    40681 cggaaaagca gtaacaataa atgtgaattt ctaaatatga ccagaaagaa ggagactaca
    40741 tggtaaagtg tagtctctat ttttatttaa tttttatagt atatacatct aaattaatta
    40801 aaatgatgta ttgtttatag tttattgcta tattttctta taaaaataaa tttaataaat
    40861 atttaaattt aatttacaaa aacaatataa atatcataat aaaataaaat tttttaatat
    40921 tactaaaaat atatagacaa aataataaca aatatagtat tatgtaattg tagaaatgct
    40981 tttcataggt atattctatg aagatgaatt gcataaaaat gaaaaaatgg aatggatatt
    41041 atttaggggt gaaaaatcat gaatccatta gttataaact tacaaaaatg tagcatacat
    41101 gatggaccag ggataagaag tacagtattt tttaaagggt gtccacttga atgtgtttgg
    41161 tgtcataatc cagagagtca aacatataca aaacaagttt tgtataatga agaaagatgt
    41221 tcaaaatgtg aagcatgtat aaatatatgc cctcataagg caatttacaa aggtgaaaca
    41281 aaaatatgct tagaccaaga taagtgtgag ttttgtgaaa cttgcttaga ctattgtgta
    41341 aacaatgcaa gagagattgt tggtcaagag tattctgtaa gagacttggt taaagagata
    41401 gagaaggata gaattttcta tgaagaatcg ggtggtggag taacactatc aggtggagaa
    41461 gtaatggctc aagatatgga cttcatttgt ggagtaataa acatgtgcaa atcaaaggga
    41521 atccatgtag caattgatac atgtggctat gcaaagtcag aaaattatga aagagttgct
    41581 aaatgtgcag atttgttttt atatgatatt aagcttattg atgaggataa gcacataaaa
    41641 tttacaggaa aatcaaatga cttaatactg aaaaatgtta agattttaag tgaattaggg
    41701 gttaacataa atataagaat accattaatt gtaggagtaa atgtagatga tgaaaattta
    41761 gaggttaaaa aaatgataga gtttttaaag cctttgaata tacaagcagt aagtcttctt
    41821 ccatatcata atattggtaa acacaagtat gataaaattt ataaaaagta tgaaggagaa
    41881 gaactacaaa gaccatcaga agaaaaatta gaggaaataa aaagactgtt tgaagcaagt
    41941 aatttcaata ctaagattgg agggtaataa aatggcaaga ggaacttttg agagaactaa
    42001 aaaattaaga gaagaaagta ttaatgcaga accacacata tctattgaaa gagcagtact
    42061 tatgacagaa gcttataaaa aatatgaggg aagtgtagag attcctgtac ttcgtgcttt
    42121 atcatttaag cattatattg agaatagaac tcttagcata aatgatggag aattaatagt
    42181 aggtgaaaaa ggtgattctc ctaatggagc accaacatat ccagaaattt gttgtcacac
    42241 aatggaagat ttagaagtaa tgcacaatag agatataata aattttagcg tatcagaaga
    42301 agctagaaaa atacataaag aagaaataat tcctttttgg aaaaaaagac aaacaagaga
    42361 taagataata aatgcaatga cacctgagtg gttagcagca tatgaagcag gtatgtttac
    42421 agagtttatg gaacaaagag ccccaggaca tacagtttgt ggagatacaa tatataaaaa
    42481 aggattttta gatttaaaga aagacataga agcaagatta aaagagctag attttcttaa
    42541 tgatttagat gcatataata aaaaagcaga tttagaagct atggcaatag cttgtgatgc
    42601 aatggttata ttaggtaaaa gatatgctga gaaagcaaga caaatggcag aagaagaaac
    42661 agatgaagct aagaaaaaag atttattact aattgctgaa acttgtgatg ttgtaccagc
    42721 tcacaaacca gaaacttatc atcaagctat acaaatgtat tggtttgttc atataggggt
    42781 tactactgaa cttaatatat gggatgcttt tactccagga agacttgacc aacatctaaa
    42841 tcctttctat gaaagagatg tagaaaatgg aatactagat agagatagag cacaagaatt
    42901 acttgaatgt ttatgggtta aatttaacaa tcagccagca ccaccaaaag ttggtataac
    42961 attaaaagaa agtagcacat atacagattt tgcaaatata aacactggtg gaataaatcc
    43021 agatggtcaa gatggtgtta atgaagttag ttatataata cttgatgtta tggatgaaat
    43081 gaaattgata caacctagtt caaatgttca aataagtaaa aagactcctc aaaaattctt
    43141 aaagagagct tgtgaaatat caagaaaagg atggggtcaa ccagcatttt ataatactga
    43201 agcaatagtt caagagctta tggaagctgg aaaaactata gaagatgcaa gacttggtgg
    43261 aaccagtggt tgtgttgaaa ctggatgttt tggtaaagaa gcatatgttc taactggata
    43321 tatgaacatt ccaaaaatac ttgaattaac attaaataat ggatatgacc caattagtaa
    43381 aaaacaaata ggtattgaaa ctggagaccc tagaaatttc caatcttatg aggaactatt
    43441 tgaagcattt aaaaagcaat tacattatat gattgacata aaaatagaag gaaatgctgt
    43501 gatagaaaat atatgtgcaa aacacatgcc ttgtccactt atgtctacaa tagttgatga
    43561 ttgtatagaa aaaggcaagg attaccaaag aggtggagca agatacaaca ctagatatat
    43621 acaaggtgtt ggtataggaa ctataacaga tagtttaaca gcaataaaat ataatgtatt
    43681 tgataagaaa aaattcgata tggatacatt gcttaaagca cttgatgcta attttgaagg
    43741 atatgaagct atacttaatt tagtttcaaa taagactcct aaatatggaa atgatgatga
    43801 ttatgctgat gaaataatgc aagagatatt caatgcatat tacaatgagg taactggtag
    43861 actaactgtt tgtggtggag aatacagagt agatatgtta ccaacaactt gtcatatata
    43921 ctttggagaa attatgggag caagtccaaa tggtagactt tgtgcaaaac cagtttcaga
    43981 gggaatttca cctgaaaaag gtggagatac taatggacct acagcagtta taaaatcttg
    44041 tgctaagatg gaccacataa aaactggtgg aacattatta aatcaaagat ttgcaccatc
    44101 agtagttcaa ggagaaaaag ggttagataa tatggctaat ctagtaagag catactttaa
    44161 tatggatggt catcatatac aatttaatgt atttgataaa aatgtactgt tagaggctca
    44221 aaagaatcct aaggattata aagacttaat agttagagtt gcaggatata gtgaccattt
    44281 caataattta agtagaacac tacaagatga gataatagga agaactgagc aaacattcta
    44341 ggtttgcttg taaataaaac ttcttactat ataaaatcgt aactgatata ataaagtata
    44401 aatggtttga ttccattttt aaaattttag attaattatg agctaacttt ctaaatagga
    44461 agttagctcg ttaagtttaa tgaaaaaatc gttaaattta tatttagtaa atcatacaca
    44521 tattagtaag taatacatac aaaagaataa tttattatag ttataataag gttatatttt
    44581 ataaaaataa gataatttta agcagttaaa ataaagtcaa tttagctact ttaaaataaa
    44641 actaatagaa aaaaggagat ttgatatgaa aactttagga tttattggtt cagggaatat
    44701 gggaagtgca atgataggtg gcatagtaca gtcaggatta gtaaaggcag aagatataac
    44761 tgtatcagat ttaagccaag ttgccttaga taaagtaaaa gaagaatttg gaataaatac
    44821 tacaactgat tcaaaggtag ctgttacaaa ttctgatgtg gtaatagtag cacttaaacc
    44881 taatatatgc gaaaaggctt taactccact taaagaatta atagatgcaa ataaaataat
    44941 agtatctata gcagcaggta aaactataga aagtctggaa agttttatag gttcagataa
    45001 aaaaatagta agagtaatgc ctaatactcc agcccttgtt ggcgagggaa tgtcagctct
    45061 ttgtaaaaat agtaatgtaa cagatgaaga gttaaatatg attaaggctc tgtttgaatc
    45121 ttttggtgag gcagaaatag tatcagaata tttaatggat acagttacag gtattagtgg
    45181 ttcttctcct gcatatgtat ttatgtttat agaagctatg gcagatgcag cagtattagc
    45241 tggaatgcca agacaacaag cttataaatt tgcatctcaa gcagtaatgg ggtcagctaa
    45301 gatggttctt gaaactggaa aacatccagg tgaattaaaa gatatggttt gttctccagc
    45361 aggaactact atagaagctg ttaaggtatt agaagaagaa ggctttagag cagcagttat
    45421 aaaatctatt gttgcttgta tagataagtc taaagatatg agcaaataac agatgtaatt
    45481 aagtttacta tatggtttct tgaattgttt ttttagtact tatttatatc tatacataaa
    45541 tgtatttggt ataagtaaaa taagagtaat ttactataaa aaggaattta atgattgagt
    45601 gagaatttat tacttaaata ttaataatta aatagatata tttttaacta tatttgagat
    45661 atatcattgt gaaaaaataa aatttataag tattattgtg aggttataag tagatttatt
    45721 taaaaataaa tttatttata gcctttttaa atttgaaata atattcataa ggtaataaaa
    45781 gttacaaata ttttcttcgc taataagttt taaaatacct ataatgtttt actttttatt
    45841 ataataaata caataaatat attcttatat aaattctatg tcagatatat ggaaagataa
    45901 gaaccttgag attatgttaa aaaatctaga ttttatactt ataaaaagtt tgattttaca
    45961 accttacaaa agagaatcaa gataggaata taattatctt tttcataaat atataaatga
    46021 tatactaata ttatagtatt attgatattt gtattggagg ttgaacatga gggatgaaat
    46081 tttaagtttt gtaaatgaat gtgtattatt taacaacttt gatgaactta aaaaagaaag
    46141 tggcataata acagaagata tagtaaaaaa gtttaattta agtagaactc aatcaagtag
    46201 attattaaat gatttagtaa aatctgataa tcttataaag ataaacagta gacctgttat
    46261 ttttttacct aaaaataaaa taaatgatgt agtaggacct acaaaaaaaa gtatttatga
    46321 aaatttagat gaacttaaaa atgagtgtaa attattaaag caagagactg tgtttaatag
    46381 tatcatagga tatgataata gcttaaaaga agtaatcgaa caaataaaaa ccgctgtact
    46441 ttatccaaat ggcggactta caataatgct gacaggtgaa agtggagtag gaaaaacttt
    46501 tttagccaag ataatataca aatatagtgt aagcagtaat gtattagaaa aaaattctcc
    46561 atacaatgtg ttaaactgtg cgcagtatta taataatttg gagttattgt ctagtctatt
    46621 atttgggcat gtaaaaggag catatactgg agcaaatgaa tctagagcag gtctaataga
    46681 acaatcagat ggtggtgttt tatttttaga tgaagtacat agattaaata gtgaaggtca
    46741 ggaaaagtta tttacattta tggatacagg tacgttttct aggattggag agaatggagt
    46801 aattagaaaa gctagggtaa gattaatatt tgcaacaaca gaaagtctat ccaaattttt
    46861 gcaaactttt ttaagaagaa tacccataaa tatttatgtt cccaatatag aagaaagagg
    46921 gactattgaa aaaagaaaga ttgtagaaca ttttatttat gaagaaagta aggtacttgg
    46981 cttgcctata gagataactc aaattacatt aaatacgatt ttaaagataa aattcaaggg
    47041 gaatataggt gaatgtaaaa atgtaataaa atatgcatgt ggacgagctt atgcaaaaaa
    47101 tcaaagaaga aatggaaata tttttgttac tcttcaagac ctccctagaa atctttatat
    47161 agaaaatgta gatatatttc aattccaaag tggtaaaagc aaaagcatta tcttttctcc
    47221 taaacaattt agtattgaaa tgtcaaatgg aagaaataaa agaaatataa tctatcaaag
    47281 tttcataaaa tgtttagact actttgatag actagaaaaa aatgaaataa caaaagaaat
    47341 atttagtaaa aagagttcta atctaatgat tagactaatg gacaatttag tcttttcaaa
    47401 taatgatgaa aataataacg tacttatgga gcttataata tcgataatgc aggatatatt
    47461 tagaaattta gaagttaata acaatataaa atacgatggg aataatgtat tggcattttc
    47521 gtcttatctt tatttgaagg acgaatctta tcaattatct gatgagtata aagctttaga
    47581 aagtaaatta ctaatatatt taaaaaaaga gagttacaaa gaatactcta taataagtaa
    47641 aatatcaaca ttaataacga atagattgga tatgtatctt aataatgtag atacaatcat
    47701 aatgattata tttattaaat caacaattat aagaatgaaa tttaatcaag ttaatgcgac
    47761 tattatagca catggatatg ctactgccag tagtatggcg aatgtatgta atcggatgtt
    47821 gggtaaaaat atatttacag ctattgatat gcctatagat gctaccattg ctgatgtatc
    47881 aaaacaaatg tctagatacc tagaaggaga taggataaag aatggtttaa ttgtgttatt
    47941 tgatatgggc tctcttaatc ttatctatga agatttaaaa aataagataa atgggccaat
    48001 gttatttata gaccaaatat ccactatttc tgcactagaa gtaggaaatt tattaatgca
    48061 aggtaaaaac attgaacaga ttgcagaaat tatggatgaa gaaactaaac ctaatataca
    48121 attgtattat cctcaaaaaa ataaagaata tgctataata tcatcttgtt ttacagggat
    48181 aggtactgct ataaaaatcc aacatctact ttccgaaagt ttaattggga tagttgatgt
    48241 caaaataata ccttatgatt atgatagtct tgtttctatg ggagataaag aaccagtttt
    48301 tgaaatgtat gatgtgatgg ctatagtagg aactgctaat ccaaatgtga atggggtgga
    48361 ttttatattg ttagaggata taatatcagg aaaaggagaa gatgatgttt ttagaatatt
    48421 tagtagagta gtagaaaatg aaaaaataaa gaacataaat gattctattg taaagaattt
    48481 ttcattaatt agagtaatag acagtctaac tattttagat tcaaaaaaga taatagagag
    48541 aatagaagaa ggaatcaatg ctatagaaaa tattcaaaag aaaaaacttc caaatgataa
    48601 aaagatttct ttatatgttc atttaagttg tatgattgaa agattagtta gacaaactga
    48661 aattgaagag tatactgata tggatttgtt aatcaaaaac catcatagtg aagtaaaact
    48721 aataaaaaat gcatttagtg tgctagaaaa gagttatagt gtgcaaatac caatttcaga
    48781 gataggatat atttataata ttatctatgg tctaccacag taaaatacaa gattacaaaa
    48841 taagtaaatg aaatttaaaa tagtatgcca gtatttggca tactttttgc ttttatagat
    48901 aaatgagagt ataaacaata aaaattttaa tgtatgatgg aggatttggg gaaaatggta
    48961 tctttgatga gaattgatga cagattgata catggtcagg ttgcatatgg atgggcaaca
    49021 tcactaggta taaatgtaat actagttgca aatgatgaag caaaaaatga ccaaatgaaa
    49081 gctatgtcac tgaatttagc gaaacctagc aatgtaactt tatatataag gggggtagag
    49141 gaatctggag aaatagtaga aaaatttgct tcttcaaaga aaagcaatgt attagtgtta
    49201 gtaaaaaata ccagagatgc tttagttgta gctaaaaatt caggaggagt attaaaagaa
    49261 ataaatgtag gagggttaag atatgaagaa ggaaaaaaga aacttacaga tttagttgct
    49321 gttgatgatg atgatataaa taactttaaa gaaataggtg atttaggaat tgatatagaa
    49381 cttagaatgt tacctagaga caaaaagaaa caactatcag atttaataaa ataatttagg
    49441 agaaagagaa tgaaaaaatt tctaattgca acacatggag aattgtctag agaacttgtt
    49501 gacacaagta aattaataat tggttcatta gctaatattg agtatttttg tatgacaaaa
    49561 gataaatcag cagatgatgc tgagaaagaa attagaagta tattatcaaa taataaagat
    49621 agtgaagaat ttgttgtttt aacagatgtg tttggtggaa gtgtggcaaa tatatgtaca
    49681 aacttacttt tgcaagggtt caaatttgaa ttgttgacag gcgtaaattt accaatgctt
    49741 ttatctatat tcttattagt tgaggaggat acaaaactaa tagttaaatc aggcttagag
    49801 gaagcaaaaa atggaattgt ttatgtaaat gagttattag aaaatcgaaa taaaatcaaa
    49861 aatgtaatgt aatttaatgt aaattaaact aagttaaaat ggaggttcaa tatgttagta
    49921 caagctacta tgttagctat tatagcagga gttggtatac tagatgggcg tatatttggt
    49981 caatctatgt ttgataggcc aatagttaca ggtatgttag ttggattagt tttaggagac
    50041 ataaaatcag gaattatgat tggtgcacag cttgaattaa tttggatggg aattgcaggg
    50101 ataggtgcag ctactcctcc agacgtagta acaggaggtg tattgggtac agcttttgct
    50161 atattatcag gtaatggtgc agaagttgct ttagcagtgg cagtgccagt agcagtatta
    50221 gcacaatctc ttggagtatt agttagaata ataaattcgt acttttctca aaaggcagtt
    50281 ttctatgcta aacaggctga ttttaagaaa gttaccataa tgatgtggtt gccagtaata
    50341 ttattctttt taagtacatc agttccaacc tttttagcaa ttatgattgg tgctgataaa
    50401 gttacaacat tgataaatgc aatacctaaa gttatattag acggattggg tgttgcagga
    50461 acattgttgc cagcagtagg ttttgcgttg cttatggata tgttgatttc aaaaaagatg
    50521 tctgtatttt tctttatagg gtttttgtta gcatcttatg gtggattaga tataactgct
    50581 atagctttat ttggagtatg tgtagcattt gtactaaact tttatatcaa taacaaagaa
    50641 aataatcaaa atcctcaatt agcaatgaat actttaacgg aaggagagat tgactttgaa
    50701 taaattaaca aaaaaagaat taagaagtat gttttggcgt tcatttgctc ttcaaggtgc
    50761 atttaattac gaaagaatgc aaaacttagg ttattgttat tcaatgttac ctgcaataaa
    50821 gaagctatat aataagaaag aaaatcaagc aaaagcaata gaaaggcatt tagagatttt
    50881 taatacaacg acagtggtag ttcctgctat attaggtata acagcagcta tggaagaaga
    50941 aaatgctaat aatccagaat ttgatgaaag ttcaattagt gctgttaaaa cagctcttat
    51001 gggacctctt gcaggaattg gtgattcatt attctgggga acatttagga ttatagcagc
    51061 aggagtagga gtatcacttg caaaagaagg caatatcttt ggaccactat tattcttatt
    51121 attatacaat ataccagcat ttgcccttag aatatttgga cttaagtatg gttataaagt
    51181 aggggtaaat tctcttgaaa gaatacaaag agagggactt atggagaaga taatgtctat
    51241 ggctacaact gtcggtttat tcgttgtagg aggaatggtt gcaactatgt tgagtataac
    51301 tactcctttg aaatttaact taaatggtgc agaagtaatt ttacaagata tactagataa
    51361 aataatacct aatatgttac ctttaacctt tgcattttta atatattaca tgttgaagag
    51421 aaaggtaagt gtaacaaaat taactatagg cactatagta acaggaatcg ctttacatgc
    51481 tataggtttg ttatagaaat taattataat ttattgaata tatagataag gaaggtgtat
    51541 aaaatgacaa tacaagatta tatgttagaa acaccagtta gaatgagaga aattatatct
    51601 aatgcagata gcttatttaa tgaagttaag agagcaaatc taaaaaagat tataataaca
    51661 ggttcaggta ctagctatca ctcaggagtg caagtgcaac catatttaca aaatttatta
    51721 gatatagatg ttgtgaaaat gtatccattt atgataactg aagatacatt caagtttgat
    51781 aatgaaaata ccctagtagt aggtgtatct caaggtggga gtagttattc tacatacaac
    51841 gctatgaagt tagctgaaga taagggttgt aaaatagcat ctatggcagg ttgtaagaat
    51901 gctttaatag atgagatttc tgattatata ttaacagtaa attgtggtga agaaaaatct
    51961 ggagctaaaa caaaaggata ttattgtaca aagttaaact taatgttatt aggtcttcaa
    52021 atagctagag aaaaaggtac aatatctagt gaaaagtaca atgaggaaat aaataagata
    52081 ttagatgcaa ttaatagatt tgaagcagtg tataagctct ctaaacaatg gattgaaaga
    52141 aacaaagaaa agttagttaa ttctaaagaa ataagaataa taggtcactc tgatatatat
    52201 ggagatacat tagaagcagc attaaaatta ttggaaacaa tgagaatacc tgtaactggg
    52261 tatgagtttg aagagtttat acacggtata tataatgcta taaatagtga ttctactata
    52321 tttatactag atacaggaaa agaacctaga gtaactaaga tgattgatgt actttctggt
    52381 tggacggaaa atgtatttgc tataggtaga gatgttacag aaaatgataa aaatttaaag
    52441 attgatatca cagataatcc ttactatcaa acatttaatt ttatagtacc tatacaacta
    52501 atatgtgggg aaatacctac attaagaggc gtagacccaa gtgttccaaa agatactagg
    52561 ttccacatga agttaggtag caagaaactg aataagtaac aaaaaaagag gttgtctcaa
    52621 aatagagata agcctctttt tgactgttga aatgatgaaa atatatttga ttttatataa
    52681 aaaagagtgc ctcatgaact aaaaagttaa ttttgagaca cccactttta tcttatttta
    52741 aactaaaata tttatatatt agtgtgtatt acttttttta ttgctgtctt ccttacttga
    52801 gcaagaatta gcacttggac atccagagca aatagaacat ccactacaga catttccgtt
    52861 ttttgtagac ttgaatttat taaacagaat aaagagtgca aggactataa ttattccacc
    52921 tatcaaagct tccattattg aattacccat aaatagtact ccacctatgc ttttaactat
    52981 aaaagccatt atccatgcta gtataaattg atatgcaaat gatgtaaaca tcattttatt
    53041 gccatattct tttttcatag ttgcaagtgc agctatacat ggagtatata aagcagtaaa
    53101 tatcaagaat gtatatgcag taactccatt aaatattgtt ggtaagacaa cagttagatt
    53161 accatatagt atatttaaag agtttactac gatttctttt gctccaagac cacttaaaat
    53221 agcaactgaa gttctccaat catcaaaacc aagaggtttg aatataggag atataatatg
    53281 acctagagta gccaagaagc ttacatttat atcttctgta tatccaaaaa cattgaatga
    53341 agaaagtccc caaattacga ctgacattgc aaacatgaca gtaacaactc ttatcaagaa
    53401 accttttgat ttattccaag tatttttaat aagtgcatct atagtaggga ttctatattc
    53461 tggtaattct aatataaatg gttcagcctc tgttttaaag gctgttttat ttaagaataa
    53521 tgcaactaca attgccataa ctatacccac caaatacagt gacgtagtta ctaaagcagc
    53581 attatgtgga aagaatatag ctacaaatag tgcatatata ggtagctttg ctccacaagt
    53641 cataagtggt gcaataagag ctgtaactct tctatctttt tcgctttcca atgttctagt
    53701 tgccattata gctggagaag aacatcccat acccataact ataggtataa aagctttacc
    53761 agatagacca acctttctca taactttatc cattaaaaat gctgttcttg acatgtatcc
    53821 actatcttca aacaacgata taccaaagaa taatgtaaat attaaaggga agaatggtaa
    53881 agtaccacca acacctccaa ttattccatc aactataagt gatttaaacc atgggctaga
    53941 gttagataac atatcactaa caggtgcaga aatataagcc tctataagac tagcaaatcc
    54001 ctcttgtagt ggtcctccga cccagtcaaa ggtaaattta aataagagga acaatacacc
    54061 aataaatatc ggatatgcta atataggatt caagactata ttgtctatct tatcactgat
    54121 agatttcttt tgtgtatatg tagtttttgt acatctcgat aaaatggatt ctaatttttt
    54181 atatgtttct gtttcacttc caaagttttt ctgatatata aaagcttttt gcgtagctcc
    54241 cttaatctct tcttctatcc tatcaacacc atttttcttt tttgctataa ttggaacaac
    54301 aattactcca agttcttcac ttaatttttt ggcatctata ttaactcctt tagattctgc
    54361 aatgtctaac atattaagca atataactat aggcttgtta aattgcataa gttgagttgt
    54421 taagtaaagg tttcttgata aattagaagc atcaactaca tttactatta catcaacatc
    54481 ttcattttct aaatatgatt tagaaacctt ttcttcattt gagaaagtat ccattgcata
    54541 tataccaggt aaatcgacaa cctttatctc ttttccaaga aatccttctt ttttttctat
    54601 agtaacacca ggccagttac ctacatattg atttgaacct gtaagtagat taaaaacagt
    54661 agttttaccg acatttgggt ttcctaataa tgctacatta atcacgggta gctcctcctc
    54721 tattattgta aagaaatatt tttagcatca gattttctaa tcgcaaggtc aaagcctcta
    54781 aatctaatta taattgggtc tccaagtggg gcaacctttt taacttctat ttcagtacta
    54841 tttatacatc caagtgcaag caatctttta gataatttaa tatctccatc tatactatta
    54901 ataaatcctt tttctcctat ttttaaatcg taaacagtca ttattaacac ctcctaatga
    54961 aattcattat cattaaaatt gtaacaagta tgatacaaaa agtcaagatt tatagaggta
    55021 attgcacatt gaaataacta atatttattc taaatagatt aaaaatattt tagtctaaat
    55081 taggtgtttt tatatatttt gtattataat gtaagatgat agataaaatt tggaggagtt
    55141 aacttaatga aaactagaaa aatgacattt ttaggtctta tgatagggta tagtttagct
    55201 ttatatgtac tagagacata tataccaaat cctcttatag ttatatttcc aggggcaaaa
    55261 ttgggtttga gcaatattat aactttaatt tcattaatgt tgttaggtgt caaagatact
    55321 gttataattg ttactatcag ggtaattttg tcatcaatat ttgcaggccc tttatcatat
    55381 ctactattta gtataggagg agcttatctg agtcttttat ttatgtattt agcgagtaaa
    55441 ataaaagatt tatcactaat agggataagc attataggtg caatagggca taatataggt
    55501 caattaatag ttgcaagttt aatcatagaa aatatacttg ctatagggta cttaccattt
    55561 atgttaatgg catcattagt aactggtatg tttgtaggct tagtatccag gtatacaata
    55621 cctaaattaa agcattttta tagtaagttt tattgacata atattgacaa aatataatat
    55681 tgtttgataa aatgtatata aaaatataca aatttgtaat agtggtgatt attatggcga
    55741 acaatgaatt agaagcgtta aaaaatgaga ttgaagcagt tagggaagag ataaatacat
    55801 acatagaata tccagaaata tttcaagaag agttagtaga atcaagtaag aaaatagata
    55861 tattaataaa taaatacatg tacctaagca aatagcccac agttgtgggt ttttttgtat
    55921 caaaaattaa cagatggcta tattttacat atattaataa taatattaag atataaaata
    55981 gtatttctga tgtgtaaatt atctgtagga cataagttgt aattaagtca ggagggtttt
    56041 atattatgat tgatatagga agtaaggaga tagcaataag gttactatta gcactaataa
    56101 taggaggaat aataggctta gagagagaaa aaataagaca gtttgcagga tttaggacac
    56161 atatactaat tgcaataggt tcttgtattg tttcaataac ttcgattcaa ttattctttg
    56221 attataattt gtatacaaat gctgacccag caagaatgcc tgctcaagta ttatctggaa
    56281 ttggtttttt aggtgcagga gcaattttaa aaaataaagg tggagtaaaa gggcttacta
    56341 cagctgctgg gatgtgggca actgcatgta ttggtatagc agttggatat ggttattatg
    56401 aattggcaat tctaggtgga ttatttgtaa tgatagcatt atttgtgctt aggataatca
    56461 atacgttttt atttagccaa gaaaagaatg tattgatatt aaaattaagc aatttggact
    56521 ctataccttt tttatatgat aaatttgaaa aaaatcaact tatcgtaaga aatatggaaa
    56581 tagaatgtcg taatgaagaa tactggaagg ttaatttttt tgtatcttat gctaagagaa
    56641 tacacttaca cgacgttatg aaagaaataa atatgataga aggagtaata aatgtagatt
    56701 atttggacta aaatatatac aatatatttt gtaaagtgaa taaaatataa aacaaattaa
    56761 aatagaggtg tatgatatgg gaactgatag aagtacaata gaagaaaagt acaaatggaa
    56821 gatagataag atgtactcca gtaaagagga aattgaaaaa gacataagta aagtaaaaaa
    56881 tcttatccaa gaagtaaaag aatataaagg gaagctttct gagagtaagg agaacttata
    56941 taaagtatta aatatctctg aaaatgcatc taggattgtt caaaatttat atgtatatac
    57001 tcatatgaaa caacatgaag atactagaat taatgataat caaggaagag ccactaagac
    57061 agaaatgtta tctactgatt taggtgtggc tacttcttat atagttccag aaatactggc
    57121 gatagaagag aataagttaa gtgaatactt aaaagatgag aagctatcct tttatacaaa
    57181 atatataaag gatatattga gagataaacc acatactttg agtgaacgag aggaagaaat
    57241 acttgcagct acatcagaat tatcgacaat tccagaaaat gtatacgata tgttagcata
    57301 tgcagatatg gaatttcctg agatagaaga tgaggagggt aataaggtta agctttctca
    57361 ttcaaactac tctttattta taaaaagtaa gaatagtaga gttagaaaag acgcttttga
    57421 aggtgaattt tcaacatatg agaaatataa aaatacattt gcctcaacgc tttatggtgg
    57481 aataaaatca gagatatttt acgcaaaaac tagaaagtat aattcagcaa tagaagcgtc
    57541 tttattttca gatgatgtaa gtttagatgt ttacaataat cttatatcag ctatagataa
    57601 aagtattcct aatctaaata aatatgttga gcttaaaaag aaatttttag gattgaatga
    57661 aatacacatg tatgatttgt atgttccttt gacagataaa tttgacatgg atataccata
    57721 tgataaagca caggatatca tattagaggc acttaaacct ttaggagaaa aatacttgaa
    57781 ggtcataaaa agtgcttttg atgaagggtg gattgatgta tatgataatg aaggtaaaaa
    57841 aggaggagct tattcttggg gaagttatga ttcacatcct tatatattaa tgagctataa
    57901 aaatgacctt aattctctat tcactttaat tcatgaatta gggcactctg ttcacagtca
    57961 ttattcaaga acaagtcaac catttttata ttcggactat aagatattcg ttgcagaagt
    58021 tgcatctaca ttaaatgaat tacttcttat aaattattta ttagaaaatt ctaagtctaa
    58081 ggatgaaact atatacttat taaattatta tttagaacaa tttagaacta cagttcatag
    58141 acaaactatg tttgctgaat ttgaaaaaat tgtacatcaa agggtagaga gtggagaacc
    58201 acttactgct gatgaattta ctaatatata ctacaaatta aatgaaaagt attacggaaa
    58261 atctgcaata gtagataaac aaataggaat agaatgggcg agaatacctc atttttattc
    58321 aaacttctat gtatataagt atgccacagg gttttctgct gcaagtgctt taagtcaaca
    58381 gatactttca gaaggaagta ctgcagtaga tagatatata aacttcttaa aaagtggagg
    58441 gtcagaatac ccactagaac aattaaaatc tgctggtgta gatatgacta aaaaagaatc
    58501 tatagaggaa gccttaaatg tatttgctga attagttaat aaactagaaa aagaattata
    58561 ggatgtgata ggttgatagc ttcaatgaag acttctgata atatgagttg tattgtgttt
    58621 atatctgcct aaagtaactt taaaaagtta atctaattaa gaataaatca tataaaatta
    58681 agtttttaca tgtatttaac aatatttaca tttacttaac cctgctctaa tattcattta
    58741 acaaagaatc tgtattatta aaatatagaa aaatgacaac aaaaaattaa aatataagcg
    58801 ggggtaagta aaatgtttaa aaagaaaata ggcgttcttt tagctagtac aatgttagtt
    58861 ggagctttag cagtaggatg tagttctaac tcaggaggtt caggtgattc aggagattca
    58921 agcaaagttt ctgtttcagg ttcaacttca ataggtcctc ttatggaaac tatcggagaa
    58981 aagtttcaag aaaaaaatca aggtgttagt gtagaagtac aacagattgg ttcttccgga
    59041 ggtataaaaa atgccataga aggaacatct gaaataggaa tgagttcaag agatttaaaa
    59101 gatgaagaaa aaagtgctgg attaaaggaa actaaaatag caatagatgg tatagcattg
    59161 ataactaata ctgcaaactc agtaaaaaac ctgacaatgg accaagttaa aggtatatat
    59221 acaggaaaga ttactaactg gaaagaagta ggaggaaatg atgcaccaat agtaatagta
    59281 tcaagagaag aaggttcagg aactagagat ggattccaag aaattgtagg gtttgattca
    59341 gaagaactaa ctaaagatgc acaaataagt gatggttcag gaaatataaa aactacagtt
    59401 gaaggaaatg aaaatgctat aggatatata tcatttggat atgttgatga gaaagtaaat
    59461 agtttaaaaa taaatgatgt tgaagcaact gatgcaaatg taatggctaa taaatatcca
    59521 atatcaagac catttatatt agttaataaa gaagatggtt tgtcagaaaa agggaaagct
    59581 ttaatagatt atatattaag tgatgaagga caagcacttg tttcagaaaa aggatttatt
    59641 aaagttaatc aataacatga attataatat aaagtaaaca tataataccc tgtgagataa
    59701 gctcataaaa atgatgcttt aacttgcagg gtattgtcta ttattgaatg tagaaatata
    59761 aatatcttta gataaaatag gtattttagt atcttatatc taaaaatatg gaaatattga
    59821 caaaataata ttacaatgtt agaataaaaa agaaatttat gaaaatatat aaaagatttt
    59881 taataaaaat attttagaaa ctgagaagta tatcttatta ttgggcatct ggagatatat
    59941 ggagttagtg gtgcaaccgg ctatgaatat aatttttata ttgcatagtc tttttttgct
    60001 ttaaaattaa caaaaatgtt gcaaaatttg aaaataagag tattagtcgt taagattttt
    60061 attgataggt gaaattttgg cttttaaagt agccatttgt tggaaaaggg aaatttttta
    60121 aaaagtataa tactattata ataagaaaat aaagttttta taaacattga gatgcaaaat
    60181 ataaaccttt tgtaacaata tatttaccaa aataatacaa tttattttat attataacca
    60241 tataaatcat ataaatcaat actcaaacta gccaatagac aagtttctag aaaaataata
    60301 aatttataag tgaaaatgac tttaagctcc attctccaac aatcggagac tttaattagt
    60361 atttaataat aaatcttaat gttcaataca atattcaaga attgttcaaa aatacttaag
    60421 tattatagtc tagtttgtaa agatattata aaataataat actagttata tatgaaaata
    60481 aaacattata atttgtaata attataaaac ttgagattat gattaaaata cctttgaatg
    60541 gagtggtgta atgtataatt tactggttgt agatgatgat gttgatattt taaatataaa
    60601 tcaaatttat ttttctaata taggttttaa tgtatataca tcagagactg ctaaagatgc
    60661 tatggatata gtagagcgta tagttttaga ctgtataatt ttggatattt cattgccaga
    60721 tatagatgga tataaaatgt gcaatgatat aaaagaaaag gttaacatac ctataatatt
    60781 tttatctaat tatgagcatg aagaagaaaa agttcgggga tttttagctg ggggggatga
    60841 ttatataaca aaaccttata gtttaaaaga acttgaactt agaatatatg ctcgtatgag
    60901 gcagtacaaa aatattacat cagttcctaa tgtgttaaag ttttcagcgt tagtaataaa
    60961 tgtaaattca agaaaagtaa cttttgatgg agaaagtata gatttaacta ctatggaatt
    61021 tgaaatatta ttgtttctag ctgaaaacaa agaacaagta ttttcgaaga tagagatata
    61081 taaccaagtt tggaaaatgc ctgatattgg agatcaacat acagtgcagg ttcatattgc
    61141 acagatgaga aaaaaaatta attctttaag cagggagcat caatacattc aaaccgtatg
    61201 gggaaaagga tataagtttg taccataagt gagatactgt aattaataaa tagttcttgt
    61261 tttatttaat actactatga aagagatgtg gttgatgcaa tgaaaaagta taatatacta
    61321 aaaggaactc tcattgtatt gatagtctct ctgttggcaa tagcaggatt aaatcttctg
    61381 tataaatatg ataataaata tacatataag tctattagag caagtaatgg aattttaact
    61441 atagataatg atactttcac taaaggtaaa cttgtctttc tgatagatga ctgggagttt
    61501 tataatcata aaatatttaa accgaatgat tttacagagc aagatataaa accagaatat
    61561 gtttttatag gtcaatatcc agatttttct atgagaaaag ggaatcagtc accatatggg
    61621 aatgctactt atcgtatgag aataaaaaat gaaggtgagg ataagctact aagtttagag
    61681 cttcctgaga ttttttccgc aagtgaagta tggataaatg gagaaatagt ttctaaatta
    61741 ggagatgtag gaacagaaaa atatagaccc aaaattaaaa attcagtagt aagttttatt
    61801 gcaaagaaag atacagaaat tataatcaat gtatcgaatt tttcacatta ttatagtggt
    61861 ttgtattatc cgcctgcatt aggagaaaca aaggacataa gtaatatgat gttttatcga
    61921 ttactttttt atagtataat ttgcttcaca acttttgcaa tagctatatt ttcgttgtct
    61981 gtatggtttc tttcaaacaa aagtaaactt tacttatatt ttggatgtat gtgtgttttc
    62041 tttgccatcc atgtatccta tccctttgta catttgttag gactgccttt ggtaagcttt
    62101 acatatgcgg ttgaagattc gtcctatttt atggtagttt tatgtattat ttgtataaat
    62161 ggaagtatat ccaaaataga agaagataaa gtgtatagat ttttaatttt accattagga
    62221 attacaatga gtatcatatc tatagtgata ccaattattc ttcttccata tgatatgtac
    62281 tttgtcaaca tatatgggaa attaatagac atatataaat atattgtatt tatatatata
    62341 ttaatgtctt cgctggtttc aatatataaa aagacatgct ctgagcatat aagttcttat
    62401 attttagttt cagtaaacac tgtttttgga attagcatat tatttgatgc agttactagt
    62461 aatagatttg agcctatatt tacagggtgg caaacagaat attgtggatt tataattgtt
    62521 attttatttt ctcttatgat gataaacagg aatagaataa taataaaaga gaatgaaaaa
    62581 cttacaagga atcttgaaca tgaagttgaa gtgagaacta atgaacttac aacattgtta
    62641 aatgaacgta aaaaattctt ggcagatgtg gcacatgatt taaaggcacc tgtttcagct
    62701 atacaatcat ttatagactt gataaaggtt ggtaatattc atgtagatga agagacaaga
    62761 acctatcttt atgctataaa tcaaaagtca aatgaagtac aaaatagagt acgtagtttg
    62821 caagaattta catcacaaga taaaagcatt ggtattagtg aaaaaatatg tctaaatgat
    62881 tttattaaag agatatatga aaataacttg ccagatacac aagcatgtgg tgtaaacttt
    62941 gaaacttaca tattggagaa aaaaatatat gcaaagataa ataaagagat gcttacaaga
    63001 gcatttgaga atttaattta taatgctttg acatttactc catttgatgg aaagataatt
    63061 ttatcaatgg ataaagaaga tggatttgca attattaaag tttctgataa tggaaaaggt
    63121 atacctccag aaaatatacc aaaggtattt gacagattct ttacagaaag agataataat
    63181 gagccaaaag ggcaagggct agggttatat attgtcaaat ccattataag agagcatggc
    63241 ggagaaatct ttgtagattc agaactagga aaaggaactg tttttacaat aaaattaagt
    63301 ctatgttttt tataataata gcttatttaa tataaaagaa taatgatatt tgggagtgat
    63361 tataatgcaa actaagatat tgataataga tggagacaag gataattgcc agaagctaaa
    63421 aggatttctg gaggaaaaag aaataagtat agatttagca tataattgtg aagaagctat
    63481 tggaaaaata tttagcaata aatatgattt aatattttta gaaataattc taactgatgg
    63541 tgatggatgg actctttgta aaaaaattag aaatgtaact acttgtccaa ttgtttatat
    63601 gacttatata aatgaagaac aaagcatttt aaatgcttta aattctggcg gagatgatta
    63661 cttaataaag cctctaaatt tagaaatatt atatgcaaaa gtaaaagcta ttttaagaag
    63721 aatgaactca tatgtaaata ataatgaaaa taatacaaaa ttagaggaat ataatagaac
    63781 tagtggagta ataaagttag aagacaaaat aataaaattg actccaacag aaaataagct
    63841 gttaaacttt tttatagaga atcctgaaaa gactctgact actaaagaga tatatgaaca
    63901 tgtatggatg aatgagtact tagaggataa ctatagtgtg gtagttgcag tgaatggatt
    63961 aagaaagaaa atagagaaag attataaaaa tcctcagaaa attataacaa taagaggagc
    64021 aggatattat tttaataaag aataataaat atattaatct cattaataat tgttataaat
    64081 gtgaaatgct aacgatatct aaactaaatt attataaaat agctgactgt aatttaattg
    64141 ataaagccta ttcttctaga ctttgccagt taaattacag tcagttttat tatatgaaaa
    64201 aatgcgtaac agaactatta ttttatagat tatatttgaa aagatagata aattgtatat
    64261 ctaaatctat atatattcat ttttatcttt aatatatgtt aaataataaa atagttacat
    64321 aataagatta agaatttctt aataaattct aatgtaaaaa atcatataaa aaaattaaat
    64381 ttagtataat atatataaat atatatagaa aggatgttta aagtctatga gtggaaaaat
    64441 tttagttgta gatgacgaac gtgatatagc tgatttaata gaagtctacc ttacaaatga
    64501 aaactatatt gtttataaat tttattctgg tcttgatgca ctaaactgca ttaatttaaa
    64561 tgaatttgac cttgcaattt tagatgttat gttgccagga gtaaatggat tttctttatg
    64621 ccaaaaaatc cgagaaaaat atacttatcc aatcattatg ttaacagcta aggatgaaga
    64681 aacagacaag attacaggct taactttagg tgcagatgat tatgttacta aacctttccg
    64741 acctttggaa cttgttgcta gagtgaaggc acagattaga agatataaga aatacagtgg
    64801 aagtttacaa tctggtgaag aactttcaca tattttttct tttttaggtc tggaattgaa
    64861 tacccaaaca tatgaatgcc atttaaatgg taaagctctt tcacttactc caacagagtt
    64921 ttctattcta catgtattat tgaaaaataa aggctctgtg gtaaattcag aaaatctttt
    64981 tcatgctatc tggaaagatg aatattacaa taaaagtaac aatactataa cagttcatat
    65041 tcgccatctt cgtgaaaaat taggtgatac tgtagatgaa gcaaaatata taaaaacaat
    65101 ttggggtgtt ggttacaaga tttgacacct atttttcttg tcaagaaggg atgtagtatt
    65161 atgaaaaaga ttaataattt tacttatagg aaactaagag ataaatataa atttataaaa
    65221 agagaaaaaa atacagaggc gtatttaaag tataaattat atataatgtt agctatctat
    65281 acaggtatag tattggtttt aatgtttatg gctgattata cgttttcaaa tttttcaaat
    65341 cctcttgtta aatggcttaa gttgagaaga gatgtattat tttttttggt ttttataatt
    65401 ggatatatca ctattttcaa tttttattgg aaaaaaccat ggaattattt aagagaaatc
    65461 atcaatgcaa cacatactat ttatcaacaa aatgatgaat tggttgaact atctaagcca
    65521 ttaaaggaaa tagagcaaca aatgaaccaa attaagatgt ctgttttgtt aagtcaacaa
    65581 gcagtgaaag aggctgaaaa taaaaagaat aaccttgtga tgtatctagc acatgatata
    65641 aggacaccac ttacttcagt tattgggtat ttgagcttat taaaagaaat acctaatatg
    65701 gataattctc aaaaatctaa gtatactgaa gttgcacttg acaaagcaca atatttagaa
    65761 aaacttatca atgaactttt tgaaataaca cgatataatt ctaatcaaat caaaattaat
    65821 ttcgaaaaag tagacctata ttatatgtta cttcaattaa aggatgaatt ttacccattg
    65881 ctgtctgaaa aaggaaatag agccattcta aaagcaaatg aaagtttaac aataaaagca
    65941 gattctgaaa aacttgcaag agtgtttaat aatatcttga aaaatgctat tgcttacagc
    66001 tatcctaata cagaaattat tatctcagcg gttcataaag acagcaaggt agatattgct
    66061 tttagaaatt atggacagac aattccagaa gaacaacttt ctgctatatt tgaaaagttc
    66121 aatcgtttag atgaagctag aaaatctgat atgggtggtg caggtttagg gctttctata
    66181 gctaaggaaa ttataaattt gcatggtggt gatattactg ttcaaagtaa agatgaagtc
    66241 acaacattta ctatatcgct tcctacatct atttagtaaa atataaatca aatattagga
    66301 ttttcttaag aaattatcta tttaatatta aaattatgag tgtctttgtt tagtaaaata
    66361 aatactaagc aagacacttt tgtttttgca ggtaagtaga taaagagagg agtttcaaat
    66421 atggaattaa aaattgaaca tgtgacaaaa aaatttaagg ataaaattgc tgtagaagat
    66481 gtttgcctta ccttaacacc aggtgtgtgg ggatttctag gagcaaacgg agcaggtaaa
    66541 actaccttga tgagaattat tacagacatt atgaaaccta ccaatggcaa aattctgtat
    66601 aatggaaaaa atatttatat aatgggtgct gagtacagaa atttactggg atttttacca
    66661 caagaatttg gtttcccaca ggatttttct gtaaaagatt atttagaata tatagcagca
    66721 ttgaaagatg taccaccaag agaagtaaaa ggaaaaatta ataatctatt ggaaattctt
    66781 acattatctg atgtaaaaaa taaaaagatt attaaattat ctggtggaat gaaacgacga
    66841 gtgggaattg cacaagccat gttaaatgac cctaaaatcc ttataatgga tgaaccaaca
    66901 gcagggcttg accctggtga gcgagtgaga tttcgtaatt ttatttcaga attttctcat
    66961 aatcgtgttg tcctaatatc tactcacatt gtatctgata ttgagtacat atcaactcaa
    67021 aatgctatta tgaaaagtgg aaaaattctt gatgtgggaa caaccgataa actggttaag
    67081 aaagtagagg gcaaagtatg ggaatgtctt atatcaaata gagatatttc aaaatatgaa
    67141 atgaatttac gtataatcaa tcagcgtagt gaaaaaaaca atcaagtatc tattcgttac
    67201 ttggcagaaa agtcacaaat tgataactct attgctgttg aaccacgact agaagattta
    67261 tatttatggt tatttccaga agcagtttat agtaaggagg ggaaataaat gcgtattttt
    67321 tatttggaaa ttaaacgagt gttgcactca cgtcgtacat taattttatt attgttggca
    67381 ttggttttat ctgcattgat ggcttttctt ccaattactt acgagggtat caattattta
    67441 gataataatg gcaaggtagt tgaattgagt ggtttagatg ctattaaata taaaaaaaca
    67501 atttatgcta ataatagtga aattagtagt ggagttgtaa caccaaaaaa attaaagcat
    67561 gctttaaata tatggaaaaa aacagaagaa aagtatggta aagtaggtag tgaagatttc
    67621 ccactagata tttattctaa aagtatttta ccaatacgcc cattgttgaa tagacttcct
    67681 gaagcatttg ctaattcaga aacaggattt gcaacagaat tatcagaaat aaatacaaat
    67741 gatttagatt ctttttatga acaatgcaaa actcatttaa atgatattat gaagattgaa
    67801 cgacaaactt ccagtgcaca aatgaaagct caagaacttt atagaaaagt agatactcca
    67861 tttgagatat acccaggtta ttctaaagat gctttcgatt atataatatt ttacattttt
    67921 atattattaa ttatatgtgt tgcaattact gcacctactt tttctggtga gtatcagaca
    67981 caatcagata gcatccttcg ttgtacgaaa catggacata ctcgtctagc gtttactaaa
    68041 atattagctc tattttctat atttatagta atgtttgttg tatgtatttc tatccatttg
    68101 gcaatttctg atttagcttt tggtactgaa tgtttgaaaa cctcatttca aatgttgttt
    68161 tctgtcatta gtctagtaaa tataaattta ctacaagcac agattcttat agctattggt
    68221 ggtctaattt caatacttgc aatggttagt ttaacattat ttttatctgc aaaatgtaag
    68281 gattctctta cttctatgct gattgctttt tctatttgct taattcctat gggaataggt
    68341 gttagttgga ttggatacct attaccacca gggggaattg gtcttaagat tagtttatta
    68401 tatcaaatga catcatttaa tttcttacac ttaggaggta tgagtttttg gacaccacac
    68461 attatactgt ttttctcagt gatagaaata cctattttta tatttttggc tattcgtacc
    68521 tattgcaaac atcaagtatc ataacaattt gatagaaata atagtgatat aaactagagg
    68581 atacgataat tatatatgta gtataaaagt taaatttagt taacaaatct taatagcaga
    68641 tataggtaat aaattataca taaactgtat tattatctat atctgctatt ttaatataga
    68701 gaaacaacag tatattgtaa agtaaatgtc aaatatagtt ttaaaagtaa aattaatgtt
    68761 aaaaaagtaa atataatttt acacttgctt aacttaatcc taatatagat ttaacttaaa
    68821 aaaagtagaa taaaagtaca ggaaatttga tgaagacgaa ttataaaaaa ttaaattttg
    68881 aatacagaac gaaaatcgat aagtatattt taatgggagg gtattatgat agtaaaatct
    68941 agattagtag gtttagaaaa aaatgacaat aatggcaata agacaaaata cgtaattgaa
    69001 aaagtagcaa aaaatatttt tctacttagt gctttagtag cagttgcaag tttacttttg
    69061 ataataggat tcgtatttta taaaggctta agaccattta tatttgaagg atattcattt
    69121 atagactttt taactggtgc agattgggtt ccttctgcca ataaatttgg aatatcatct
    69181 atgatagtag catcaatatt tgcaacactt ggagcacttg tgataggagt acctgttggt
    69241 atattaacct ctgtatttat agcagaagta gcacctaaaa gattagcaaa aataatgtca
    69301 ccagcagttg aacttttagc aggtatacct tcagtattat atggtgtatt tggtcttgca
    69361 gtgatagttc caactataca aagtatattt aatcttccaa aaggtcaaag tttgttagca
    69421 atagtaatag tattagcagt aatgatgtta ccaacaataa tatctgtatc agaaacagca
    69481 ataagagcag taccaaaagc atacaaagaa ggttcattag cacttggtgc atcaaaaata
    69541 gaaacaatat tcaaagttgt actacctgct gcgaaatctg gagtattagc tgcagtagta
    69601 ttaggagtag gaagagcttt aggtgaaaca atggcagtaa tacttgttgc aggaaactca
    69661 ccagttatgc caactgcaat aacagatagt gtaagaccac ttacaactaa tatagcactt
    69721 gaaatgggat acgcatttgg tacacatcaa gaaatgttat ttgcaactgg agtagtattg
    69781 tttacattta tattaatttt aaacttagtt ttaaataaac tttcaaataa ggcggtaaat
    69841 taagatgaga aagttcaaag agaatctatt gaagtcatta gtatatctat cagcactatt
    69901 tacaatagta tcattagtca ttatagtggg atttatattt ataaagggaa ttggcaacat
    69961 gaattttaat ttcttattta gcaattattc agcatcaggt gatggtggta tacttccaat
    70021 gataattaca acattatata cagtagtagt ttctatagtt gtagcaactc ctataggaat
    70081 attggctgct atatatttac aagaatatgc taaaaaagga aaagcagtta cagctataag
    70141 atttgcaact gaaagtttat cagggatacc atctatagta tatggattat ttggaggaat
    70201 tttctttgta gttacattaa aaatgggata ttccatagtt gcaggttcac ttacagttgc
    70261 aataataata ttaccagtaa taattcgtac aacagaagaa gctttaaaaa cagttcctca
    70321 agcttataga gaatcatcat tggcattagg agctacaaaa tttcaaactt tatataaggt
    70381 agtacttcca agtgcaatac caggaatctt atctggagta atcttatcag ttggtcgtat
    70441 aattggagaa tcagctgcaa tattacttac agcaggtact gtagccaaga tgccaggtgg
    70501 aatatttgat agtgcaagaa cattaactgt acactcatac ttactgacta aagagagtgg
    70561 agatatagca acagcagcca gtataggaat tgttttaata gtaattgtat tagcactaaa
    70621 catgctagca agatttgttg ctaagaaatt aaataaagct aattattaaa tttaagaggt
    70681 gtgaataatg gaattaatcg ataagataaa aatgagtgta aaagatttgg atttatttta
    70741 tggtgataag caagcattaa agaaaataaa tatggatata aaagagaata aggttactgc
    70801 tttaataggt ccatctggat gcggaaaatc aacttttata agaacgttaa atagaatgaa
    70861 tgacttaatc gaagatgtaa caattaaagg aaacatttct gttgatggag aggacatata
    70921 tacctcagat gatgttataa atcttcgtac taaagtagga atggtatttc aaaaaccaaa
    70981 tccatttcct atgagtatat atgataatgt ggcatatggt cctcgtacac atggactaag
    71041 agataagaag caattagata aaattgtaga agaaagctta aaaggtgcag ctatttggga
    71101 tgaggttaaa gacaggctta aatcatctgc actaggactt tctggtggtc aacaacagcg
    71161 tatatgtata gcaagagcaa ttgctatgag accagaagtt attcttatgg atgaacctac
    71221 atctgcttta gacccaattt caacattaaa agtagaggaa cttatagagg atttaaaaaa
    71281 agactacaca atagtcatag ttacacataa tatgcaacaa gctgctcgta tatcagatga
    71341 aacagctttt ttcttaaatg gagaggttat agaatttagc gatacaaaaa ctatgtttac
    71401 cactcctgta gataaaagaa cagaagacta tataacaggt agatttggtt aaaatatata
    71461 actataaagg agttagacaa tggtcaataa tagtttagat ataagtattg atactttaaa
    71521 agaacaaaca gtacttatga tggaaaaatg tgaagaagca atagaaaagt ctgtgacttg
    71581 tatgatagag aaggatttag agggtgcaag aaaagtagta gaagatgatg aagaaataaa
    71641 taaattaaga gaagaaataa gagataagag tatagagcta atagtattaa agcaaccaat
    71701 ggcaagggac ttaagattta tttattcatt aggtaatata tcgatagagt tggaaagaat
    71761 aggagattat gcagcaaata tagctagaga aatgttgaag ataggtggag aggcttatat
    71821 aaaagagctg atagatattc ctaagatggc aaaagaatgt aagtctatga tgtctcagac
    71881 tagagaagct ttaatcttat ttgatgcaag tatagcttat gatgttggaa ctaaagatga
    71941 tattgtagat ggattgtatg aacaagtaca aattgattgt ttaaaaataa tgcatgaaaa
    72001 ttcaaatact atagaccaag gagtaaaact tctacttata ggaagatacc ttgaaagaat
    72061 tggagaccat ataacaaatg tatgtgagaa gataattttt gcaattgagg gtaaaatggt
    72121 tgagatagga taaaaaactg ctttaaagca gtttttttat tgtctaaatt aagaaagaat
    72181 tgataaaaaa atatgattaa tgggtaaatt taaaaaattg tgatatacta ggaacatatt
    72241 aaatatgagg atgcgtattt tatataaggt gctttttagg aggtggaact ttgaaacttc
    72301 aaaagatggg tatgaggact ataaaaacag gaattagtgt cactttatgt atgattcttg
    72361 gtaactatct agtagagaat atgttttatt ctctagtagc atgtataatt tctgttcaag
    72421 atacggtaaa aggttcttta aagacaggaa tcaatagagt ggaaggtact attttaggtg
    72481 gtataatagg attcatattt gccatcatta aagctggaga ccctttttta tgtggtctag
    72541 gagtaatgtg ctcaatatat ttatgcaatc tgtttaaaat aaagtcagta gtagttgcct
    72601 gtgtaacctt tctggctata catctaggtg taggaaatag tgaccctgtg tattattctt
    72661 tacatagagt gttagataca tctgtaggtg ttttgtttgg agtacttgtt aattattatg
    72721 tggctagacc aaattatcta aatagtgtta tagatgaatt taaaaagata gaagaacttt
    72781 caatgttact tattgaagat aaaattctta gaaaagaaaa tttaaatgta gagaaatttg
    72841 aagaagaagt agaaaaatta gaagaaatat attcaaaact tattgatgag ttggattata
    72901 gtttgagtga aactaatata gaaaaaattg agaatgcctt aaggatatgt agagaaatac
    72961 attttcatat gcagtctata gagttacttg aaaataaact ttatttgaaa gagcatacat
    73021 ataaatacct taagaaaaca tataatgtgg ataagctaga ctggaatata gatgaagaaa
    73081 aaagccccgt attcaactat catctaatga aaataatgat tgaaatagag ttgttgagaa
    73141 agctaaataa atcatattaa taatagtagt taaataataa ataaaaaata gtatctttgt
    73201 aaatattaaa catatataag tttaatttat ggaggtacta ttttttatga atactagaaa
    73261 tgacaattct aaaatactag aaatatataa aatgaagctt tttggcgaac ttgtaaaagc
    73321 agtgtggaat gatgatatag aggatattga aaacttacct aataaaattt taaatgaaga
    73381 tttaaaggat aatttaaata attattttag tggaaaattt gataaagata ctatggtaaa
    73441 tttaattagg gtaactatgg gattggatgt gacagaagat acagataaaa atttaaaaga
    73501 gtcactacat gaagctgtaa atttagatga agtcaaaaga ccaataatat ctgtaatatc
    73561 agatgcttgc aaatattgtg atgaaaataa taaggaagat gagtcatgta agataagaag
    73621 taagcatatt aattgtaatg aggaagatgt atgtagtgct tgtggtgatt gtgtatcaag
    73681 atgtaagttg ggtgcaattt cagataaaat agaatttata ccaatgataa aattgttaaa
    73741 agatataaag agccctgtat atgcaatagt tgcaccagct tttgtaggac agtttgggaa
    73801 agatgtaagc cctggtaaat taagaactgc attaaaaaag ataggatttg aagatatgat
    73861 agaagttgct ttggcagcag atatgcttac tgcaaaagaa gcatatgatt attatgagca
    73921 tatgaaaaag gacgaagaag gatgctttat aactagttgt tgctgtccta tttgggttag
    73981 tttgatacaa aatagttttc ctcagatatt ggagaatgta tcaccatccg tttctcctat
    74041 gattgcttgt gggagagctg taaaaatttt aaatccagat gctaaagttg tattcatagg
    74101 tccttgtatg gcaaaaaaga aagaagcaat gttagaagat ataaaagatg cagttgattt
    74161 tgtgcttaca tttaaagagt tgcaagaaat atttgatgca ttagagttaa atccagcaat
    74221 aatggatgag agtaatagag tagaggcgtc cctttcaggt agagtttatg ctagaacagg
    74281 aggtgtaagt aaagcagtta agttatcagt cagaagaatt gacaaaaata taaaatttga
    74341 agaaaaggca tttgaaggaa caaaagagtg catggacggt ctaaagaaag ttctaaataa
    74401 agaaatagaa gctacattta tagaaggaat ggggtgtgta ggaggctgtg taggaggtcc
    74461 gaagcgtatt ttaagtgtgg aagaaggtac taagaatgtt gatgaatata gtgaaagtac
    74521 gaatatggaa actccatttg ataatttaaa tgtattacaa tttttaactt ctttgggaat
    74581 caaaagagta gaatctttag gagaaaaaga agaagaaaag gttaaaaaaa tatttagtag
    74641 agatataaaa agtaataaga aagagaataa atataaaaaa taacttttta agtcttaaac
    74701 ttatgctttt ataaaaggga gatatggggg atgaaaatta aagataataa ggctgttttt
    74761 catgtattta taaggatatt tcttatagct gttttaattt taactggaac attattggag
    74821 gaaaaaatta ataatgttcc agttgaaaat ataagttcaa aaggtgaaaa tacactggaa
    74881 ctgctttctc aaagtaatac tttaggagaa atcatataca aagcatctca agaagaaaca
    74941 aaaggtccag gggctacttc tgaaaaagta gcatacataa caatagatga tggtccatca
    75001 aaatatacaa atgcactact tgatatttta aaagaaaatg atgtcaaagc gacatttttt
    75061 atgcttaatc aaaatatgaa aaatcacaag gaagaagtaa ggagagtctt ggaagaggaa
    75121 aactcaatag gttttcatag tgtaagtcat gatatacata agttatataa aagcccagaa
    75181 gtaacagttg gggaatttaa tacatgcaat aatactctac aagaaataac tggtcagagt
    75241 tcaaaattaa taagattacc atacggaagt aaaccatata tgccagaagg ttcatataat
    75301 aaacttatgg caaatgatta tttaatttgg gactggaatt tggatacaca ggattggaag
    75361 tcttctacaa gtcagatagt aagtaatata ttatattatg gaagaaaaag agatgaatta
    75421 gtagtattaa ttcatgagaa agagcaaagt ttaaatgctt taaataatat tataagaatc
    75481 ttaaaagaga gaggatatac aatattgcca attacagaaa atataacacc taaaaatttc
    75541 tggcaagaaa acttataata aatttaaata tagtaaaaga taaagtaaat tatttataaa
    75601 ataaaacata taatataaaa aatacgaata agaggtatac tgtaaggata atataatata
    75661 aaattaatga gaaagcatta aaattaaaat aaaataatct tgcaattatt gacattataa
    75721 gacagaataa ctgtaaaaac atattttaaa atataacaac tatataaaag agaatagaca
    75781 taattaagaa aattcagaaa aaataaaata aaaataattg acaaagagaa taatatttgt
    75841 atataataat atgtaatatt aaagactgag aagaagagga gtaagtaaat actactaaaa
    75901 gagaggaaaa ttcactggct gtaagatttt ctaagtataa gatttactga atgtagcttt
    75961 ggagtttcta aactgaacta taagtaagtt tagacggtta gaaccgttaa attctttgag
    76021 agtcaaagtt gataaaataa cattaactaa taatttaatt atatgttaat gtattttaag
    76081 ctttggaatt aaggtggtaa cgcgagcttt tcgtcctttt taaagaggat gaagagctct
    76141 tttttatttc taaagatatt taaaaaattt atttataaaa tacaggaggc aggacaatgg
    76201 aaaatacgaa tttatcaaaa acttataacc caaaagattt tgaggctagg ctatataaaa
    76261 aatggatgga tgaagggtat tttaaatcta aaccaaatcc agataaaaaa ccatttacaa
    76321 taatgatgcc accaccaaat ataacagggc aattgcatat gggacacgct cttgaccata
    76381 cacttcaaga tatattaatc agatggaaac gtatggatgg atatgaagct ttttggcttc
    76441 caggaactga ccatgcttct atagcaacag aagttaaagt tgttgaaaga ataaaaaaac
    76501 aagaaggcaa gacaaagtat gaaataggta gagaagaatt tttaaagaga gcctgggaat
    76561 ggaaagatga atttggagga aaaatatcta atcagcttaa acaactaggt gattcttgtg
    76621 attgggataa agaaagattt actatggatg aagggtgtaa tgaagcagtt atagaatttt
    76681 ttgtaagcct atatgaaaaa ggtcacatat acagaggaaa tagaataata aactggtgcc
    76741 cagattgcaa aactacttta tcagatgcag aagttgaaca tgaagaacac gacggaaact
    76801 tttatcatat aaagtaccca ctaaaagata gtgaagactt tttagaaata gctacaacta
    76861 gacctgagac aatgatagga gatactggta tagcagtaaa tccagaagat gatagatata
    76921 aacatttaat aggaaaaaca gcaatacttc cattagtagg aagagaactt ccaatagttg
    76981 cagatagtta tgttgattta gagtttggaa ctggtgcagt taagatgact ccagcacatg
    77041 accctaatga ttttgaagta ggattaagac ataatcttga gcagttaaat actatgaatg
    77101 aagatggaac tatgaatgaa gtttgtggaa aatatgaagg tatggataga tttgagtgta
    77161 gaaaagctat cgtagcagac ttaaaagaac aaggttacct aattaagata aaagcgcata
    77221 atcataatgt aggaacttgt tatagatgcc atacagtagt tgagcctaga ttatcagagc
    77281 aatggtttgt taagatggaa gaacttgcaa aaccagctat agatattctt aaaaaaggag
    77341 aattagaatt tgttccagat aaatttgata aaacttattt acaatggcta gaaaatataa
    77401 gagattggtg tatatcaaga caattatggt ggggtcatca aataccagct tattattgtc
    77461 aagagtgtgg agaaatagta gttgctagaa aaatgccaga taagtgtcct aaatgtggaa
    77521 gcactcattt taaacaagat gaagatgcct tagatacttg gttcagttct gcattatggc
    77581 ctttctctac tctaggatgg ccaaataaga ctgaagcttt agattattat tatccaacaa
    77641 gtgtacttgt tacaggatac gatataatat tcttctgggt agttagaatg gcatttgcag
    77701 gtatgttctg tatgaatgaa aagccatttg accatgtttt ggttcatgga ttagtaagag
    77761 attctcaagg tagaaaaatg agtaaatctt taggaaatgg tatagaccca ttggagataa
    77821 tcgagcaata tggagctgat gccctaagat ttacattaac aactggaaat tccccaggaa
    77881 atgatatgag attctatatg gaaagagtag aatttgctag aaactttgca aataagttgt
    77941 ggaatgcatc aagatttgta tttatgaata ttgatgaaga tataattaaa aacatgacta
    78001 gagaaagtgt taaagaggac ttaactctag ctgataaatg gataatatca agagcaaata
    78061 atattgtaaa agaagcaact aataacatgg ataagtttga tttaggaata gcacttcaaa
    78121 agatatacga ttttacttgg tcagaatact gtgactggta tattgaaatg gttaaaccta
    78181 gattatatgg ggaagatgca aatgctaaat ctgcagcatt atatacatta acttatgttc
    78241 ttgaaaaaat attaaaatta ttacatccat acatgccatt tataacagag gaaatatata
    78301 ctcatcttcc tactgttgaa ggatgtataa tagtatctga atggccaaaa tataatgaag
    78361 aagataacat ggctgaagaa gaagatatga tgaacttatt gatggaaggt ataagaagta
    78421 taagaaatgt gagagcagaa atgaatgtac caccttctaa gaaagctaaa ttgataataa
    78481 tcccaagtga agaaaaaata gaagctattg agcttggtaa agactatttt ataactctag
    78541 catctgcttc aaatgtagag atagcaaaag ataaatctaa tgttccagaa gatgcagttg
    78601 gagtagttat tgatggtgtt gaaatattta tacctcttaa tgaattagtt gattttgaaa
    78661 aagaaattga gagattgtct aaagaaaaga aaaagttaga aggcgaaata aagagagtta
    78721 atggaaagct tgcaaatcaa ggtttcttag caaaagctcc tgaaagttta attgaagaag
    78781 aaaaagtaaa aaaagaaaaa tttgaagaga tgattaaatc tgttgaggaa agattaacaa
    78841 atttagaatc taaaataaaa taaatataag aattagtaaa aacatacaaa aagtatatat
    78901 tctatacttt ttgtatgttt ttctttatat atatacaaat atgatgttat aattctttac
    78961 agatgtgtta tatttttatt ttatgttgtg aatatatgaa ttttatgtct taaaatttat
    79021 aagcaataaa aatttgatat attatgatgt ttaatatagg gtaataaata catattatat
    79081 ttattttact atattttttt acataatata tctagaaaag tataggaatt tatcgtaatt
    79141 taagtttaaa tattaaagag aatttctata agtagtttaa tcgacaactt aaatttataa
    79201 agaaatttaa atttgaaagc tagtgagtac agtttggaaa ttgaaataaa gtaaactaaa
    79261 tgatatttta gatttggagg tgatattatg ttcagggtag ttatatgtga tgacgaaaaa
    79321 atacaaagaa gcatactaaa agagtttaca aaaaaacttt tgtctgaaag atgtctaaat
    79381 tatcaaatac tggaattttc ctgtggagaa gatttaatat ccaaataccc agaaaaaatt
    79441 gatattatat ttttagatat ccaaatgaaa gatatcaatg gaattgaggt ggctaaaaaa
    79501 ataagaaagt ttgatgaaaa agtagaaatt atatttacaa cagctttttc agagtatgcc
    79561 ccccaaggtt atgaggttcg tgcttataga tatttagtaa agcctataga gtatagtaac
    79621 tttgcaatgg gtgtaaatct ttgtattgat aaccttcaaa gaaagaagga gcgttatata
    79681 gttttaaata gtaaaaaagg atttaataga atactgatag attctatttt atatgttgaa
    79741 actgtaaaga gagatttagt tgtacataca ataggtagag attataaagc taatatgagc
    79801 atgaaacaag cagaaaaatt actgtgtgaa aatggctttt ttagatgtca tacaagtttt
    79861 attgttaatt taagaagaat agaagatctt agggataata tgattactat taatgaacaa
    79921 tttataccta taagtaagta tagacttaaa gatttaaaag tagcattaac aagcttgtta
    79981 tgtgatataa tgtattaatt ttaaaaaggt aattgaaaat atcgtaaaaa agatttaatg
    80041 tcatcacagg gctattgatt aaaactgtct taatatataa aatgttattt atattaagac
    80101 agttttatta tgcaaaatat cagtttatag acttttaata ttgtttaata tgtatatgta
    80161 gagtttccat tacagtagca tgattattaa ttagtagcct gattattaat atactattat
    80221 tgatttttat atgcattata tgtattttta gaatatgatt acctttttaa aataatgact
    80281 atttataaaa ctctatagat atttgtttca tttagctatg catactttaa ttaattatat
    80341 taatatttaa tggagtataa tataaatatt aaagcgacat cttatagttt attgaaccta
    80401 tagtaatgaa ttaataaatg gtttaattct atgaaaagat ttccttttat gcaatttatt
    80461 tattgaaata tgatataata tataaaggtg taagtattag ttgttaaaat aatatttata
    80521 ttagttttta tgcatacttg gtataagttt ttcatatatt ggttaaaatt gatgttgatt
    80581 tattattttt agtatttttt caccttttga ttcatacttt gtagaatggt gtattttata
    80641 aaactgatta taagacaagt tcattcaaat tagcattttt atatcatata aataattgtt
    80701 ccccctaaat aagatttaga tgtatagtat taaaatcaaa aagtataaaa taaaattgat
    80761 gcttaatcat agataaatat taataaaata tacaagggga ttgtctaata aaaagataat
    80821 ctcctttttt acaaataatc ctaaattgtg atataaatct aaaaatttta tcttaacatt
    80881 taaccattta atgataataa ttgatataat aaatataaat taaatatatg gtgtacttat
    80941 tttatgtttt tagcaagaaa tatagcattt aaaagataaa ttgtgcaact taaatcaaag
    81001 tttaagatga actattaaca tagatatatt aaaaactttt gtaatggaga atatatgtga
    81061 tatgaataat aaagttaagg ttgcagtatt agatacagga atagacaaag aacatgatta
    81121 cttaaaagat aatttagttg gaggaattgc ttttgaatgt atgcatgatt atatctttat
    81181 atcagataaa tttgatgatg aagatggtca tggaactgct tgtgcatcaa taataaagaa
    81241 agagtatgaa gatgtagagt tatttgtaat aaaaattttg agaaaagatg gtattacaaa
    81301 tataaaagtt cttgaagaag cattaagata ccttttagac actaacataa gattaattaa
    81361 tttaagttta tcagtcatag gagtagagag tgttaagggc ttatttgaag tttgttacga
    81421 attgtttaga aaaggaaaaa taatagtatg ttcactcgct aatgattttg atttaagtta
    81481 tccagctatg tttaacaatg ttataggtgt aagaggattt actttagatg gagatgattc
    81541 attttggtac aacaaaaaat atgatgttca atgtgttatg gatagcaatt catatataag
    81601 ttgtgatata aataattcct atagattacc accaaaatgt aatagttatt tatcagcaaa
    81661 gcttactggt aaaatagcta agatattatc agaaaaacca ggcataacaa tatctgattt
    81721 aaatgataag cttgaatcat tagcaactag aaatcattgg gatagttgtg attttgatga
    81781 gtgtagtaga attgtaaact ttaaattgga tttgtatgac aaagaaaatg ctcttcttat
    81841 gaaagttgct gacgttgtta gggattgttt agatattgaa gataataatg aaaaactctt
    81901 taagggtagc ctttttaata aggagatagg tttggtttat gataattgtt ttaatctgtt
    81961 gaaaaagcta gagcatagat ttgacataaa gtttaattat atggacatct caaaatatga
    82021 cttagtttca atatatacac tgactgaatt agtggaaaga tataaaaact tataaataaa
    82081 gatttgtagc taaatttaat gtagaaggta ttaaattata tgtattcttt gtcggtagat
    82141 taaaagtaaa aaatatacta taattagata gcataagaga aaatgccaat acagggggag
    82201 ttagataatg aaatatgaag aagcattaga gtacatatca caaactaata aattcggtat
    82261 aagattagga ttagaaaata tcggaaagtt attagaatta ttaggaaatc cacaagaaac
    82321 tttgaatata atacatgtag ctggaactaa tggaaaaggt tctgtgtgtt cttttgtttc
    82381 taatatacta agagagtgtg gatataaagt tggtttatat acatctccat atttagaaac
    82441 ttttactgag cgtataagag taaatggaca aaatatacca caggatgatg ttgctagaat
    82501 aattgagtta ataaaagaaa aaatagagat tatggtaaaa gaaggctatg catatccaac
    82561 agaatttgaa gtggttactg caatggcatt ttattactat tcagaacaaa aggtagactt
    82621 tgtggcatta gaagttggtt taggtggcag atatgatgct acaaatataa taacaaaatc
    82681 acttgtaagt gtgatagtat ctataagttt ggaccataca ggtatacttg gagatacaat
    82741 agaaaaaata gcgtacgaaa aggctggaat aataaaggaa aatggagtag tactagtata
    82801 tgaccagact gatgaagcga aggatgttat aaagtcagtt tgtaaagaga aaaaagctaa
    82861 atatatagaa gttgattttg atgatataaa cataaaaaaa tcagatataa attctcaaat
    82921 atacgattgt actgtaatga aagaaactta tagagacctt gaaataaaat tgataggtga
    82981 acatcaaata aacaattcta tcttggcaat tagtgtaata aaatatctaa aagacataaa
    83041 taaattagca aatataaatg aagaatctat aagaaaagga cttataaata ctaaatggcc
    83101 aggaagaata gaaaagataa aagaaaatcc aatttttata atagatggtg cacataatga
    83161 agatggagca aaatctttgg caaaagcact tgataagaat tttaaaggta gaaaattaac
    83221 cttattaata ggtatgttag aagataaaga tattgatagt gttttagaga tattgttgcc
    83281 acattttaat aaggtaataa caacaacacc aaataaccca agggccataa attcagatat
    83341 attaagagaa aaagtattaa aatatgtaga tgatgtaaca tcaaagcatg agatagagga
    83401 tgcagtaaat tatacattag aaacatcaag tgaggatgat attataataa gtgcaggttc
    83461 attatatatg attggtacag tgagaacttt agtaaagaaa ttataatttt ataaaataaa
    83521 tatacaaata aagatataaa aaagagttgt ctaaaaaatg gacaactctt tttatataaa
    83581 gtaagttttt aataatttta ctgatgttta tataagtaat tatatagatt gacgtatagc
    83641 cttagataat tggtctgggc aagaagtacc ttttccacca cagtcaatac cgtttaattt
    83701 atcagcaact tcaagagcat tttggccgat tattaagctt ctaagtcctg ataaattacc
    83761 attacatcct cctataaact cagcatcaac aatcacatta ttttcatcaa cttcaaaaat
    83821 catttctcta caacatacac cacttggatt aaatgttact ttcattaaaa agacctccat
    83881 taaatattat ttcttttttt aacaataata ataataccaa atatatgcgt aataatgcaa
    83941 ctataaagca taatacaagc taatgaaata atatattatt gtagtatatg tattgtagag
    84001 aggaggggtt atatgaaaat ctatatttct aactacttat caaagagtat tagcatagtt
    84061 gattattcta cacttgaact agaaaaagaa atagtattag aagataatat atatccacac
    84121 catttttgca tagaaaaaga aaaaaattta atatacatac ctagttcaag taatgggata
    84181 ctttatgtct tagatttaag taatgataaa ataattgata ctgtctctat aggaggaagt
    84241 cttagtcaag ttgtacttag tgataatgaa ttgtttgtgg caaatgaaga ttctaatagt
    84301 atatatgtac tagataaaaa cacattaaat ccaataggaa ttattggagt tgataatatg
    84361 ccacatggat ttgactttga tagagaaagt aaaaaattat atgtaccgtg tataaactcg
    84421 atagtatgta tagatacaat taataaaaat atacaaaaga aaataaatat ggactttaga
    84481 gcttggcata tagagcttga taaacaaaag aaagaaatgt atatatcaac acttgatgga
    84541 aagcttataa taatagatga agtaagcatg gatataaaaa aggtattata tgaattttta
    84601 ttaccagtag aaataagatt taattatagt ggcaaaaaag tttatgttgc tgatttgggt
    84661 tataataatg taagaatttt agattataca acgagtagat acattggaaa tattgaaata
    84721 aatgggattc ctcaaggctt agaaatatct aaagatgaaa agctactatt tgtatcagat
    84781 acacaagaaa attcagtaaa agtttatgaa actgcaaaca ataaattaat aaaagaaatc
    84841 aaggtaggaa aagagcctac aactataatt tgtttgtagg ctttaatgta tgtctcttat
    84901 aagtaaatcg ataacttcgg catacatata agatgcatta tttttccagt tattgcaaat
    84961 aagttttgct tgtttctctg atgaaacatt tagatttaaa tctattaagt tagactgatt
    85021 ttctatgact ctaaggttga caataaattc attatcactt tgttttacaa aactagactt
    85081 tacttgagta tctgctagta gattttcttt gttagaatct atatacttgt ctattttttc
    85141 agtaacacta gtaggtattc gattaaagaa gtattctaga ctttctacgc ctctttgagt
    85201 aagagcataa tattctctgt cagagtcttt atatgtagtc aaaaacttag attccataag
    85261 ctgagataaa agctgttgta atgaaaaata attcatcatc tcagtctcta atactacttg
    85321 agttatttga gaattagtta aatccatttt aattttttct aatatatata aaattaaaag
    85381 tttgtgatag gctaattctt cagacgagtt ttcaaacata aatatcatcc tccgtcaaac
    85441 tatttctata tataatatat taaactaatt tgtacaaaat taaaagaaca atttgtattg
    85501 tattattaat ctttaataat tcatataaaa caattttata aataaatata gagaaacagg
    85561 gctgctaatt agcagccctg ttgataccca ggtgtcaaaa tttactattt attttccagc
    85621 catttgtctt tcagccattt caactaattt cttagtcata tatccaccaa catatccatt
    85681 ttctctagct gttaagttac ctttatctat gttttcatag ttagataaac ctatttcgtt
    85741 agctatttct aatttcattt ggtttaaagc agcttttgct tctggaacta ctgttctgtt
    85801 tgaatttgac atagtaaatt tcctcctcaa ataattagtt tatgatgtct aacaacactt
    85861 ttatttatgt gatgttaata ctaatttctc caaaataaaa ataatatata cagaaaaata
    85921 aaggtaaaaa tgtaaaaaat ataaaaaaat taaataaatg agtattttag agagtttaat
    85981 taggtcaata taggttttat ttttttagtt attgtcttat aaattaaata ttacagtact
    86041 tttttgagct gaaaaaaaat aaattttaaa tatagaagaa attatttcaa agggggaata
    86101 gtatgaaaag agaagttaaa aggactaaag ctttgatata tagtgtttta tttttttcat
    86161 tattattagt gttaatattt gtttttgttt atggaataaa atacatatgt tctaaatacg
    86221 acaattcaaa aatgcctata tataaagttg atacaaatga gaaaaaaata gccttgagtt
    86281 ttgatgtagc atggggaact gataatatgg atgatatttt aaaaatttta gataaacata
    86341 atgtaaaagc taccttcttt ttagttggta gttgggtgga tgataatgaa gaaattgtaa
    86401 aagctataga tgaaaaagga catgaaattg gaaatcattc aaacactcat gccaatttga
    86461 aggaaatatc aaaagaagac ataacaaaag agatagaaac tacatcagaa aaaatatata
    86521 atataacagg aaaaaagact aatttattta gacctccttt tggggacgta aacaataaag
    86581 ctatggacat ttgtagtgat ttaggttata aagtaattaa gtgggatgta gattctatag
    86641 attggaagga gcttggacca aatcatgtaa ttgagaaagt aataaaagaa tctcaacctg
    86701 gttcaatagt tttattccat gctaatataa atgatgtaga taactatttg gatactataa
    86761 taagtcgact aaaaaaagat ggatacagtc tagtcaaaat atctgatttg ttgtataaag
    86821 ataattatgt agttgattcc aatggagtgc aaaaaactaa gaattaataa gtaataaatg
    86881 tatattttaa gtaaagttgt gataaattat atagtatatg ttagaaaagt gtcgataaaa
    86941 agacggtgtc tattttttga cactttttat acatgtatgc aatatcaata attatagatt
    87001 aaattgatta aaaaagtgtc taataattga cttttttttg atggatttaa aaatttagaa
    87061 gaattaatga atgctgtaag acagtatttc caaagggtat aagtttgttt aaaagttggc
    87121 atagaaattg ctttgttaat aagcgatatg ttctatagaa ataaacaata tgttaagacc
    87181 ttataataga aaaatagcat taacattatt tgaacagctt ataaaaaaat taatatactt
    87241 aagggggcgt actagttgaa caaactatat tctattttat taaaacaaca cgttggtggt
    87301 ccagataagc cagtagtaag tgttggagat gtagtaaaaa aaggaactct aatcgcagaa
    87361 ccaactggat taggggcaaa tatttatgcc agtgttagtg gaaaaataag tgaaataaat
    87421 gaccaagcga tagtaattga agctgatgaa gtacaagaag atacttttga accattaaaa
    87481 ggagaaggta tacttgactt aattaaagaa gctggagtag taggaatggg tggagcagga
    87541 ttccctactc atgtaaaatt aaacatagat ttaaatggtg gaacaatatt agcaaatgca
    87601 gctgaatgtg aacctttatt agctcataat ataaaagaaa tagaagaaag accagaaata
    87661 gtttatcaag gtataaaata tgctatggaa gttactaatg ctggaaaagg tatgctagca
    87721 ataaaaagca agcatccaaa agcaatagaa gctttcaaaa aagtaataaa gccaggagac
    87781 aacatagaag ttgcagaact agttgatatg tacccaatgg gagaagagag agcaatagta
    87841 agagacgttc taggaaaatt acttgagcca actcaattac cttcagaggc taatgcagta
    87901 gtaataaacg tagaaacact aactagaata gtagaggctg ttgagcaaaa aagaccagtt
    87961 atatctaaaa atataactgt agttggtcaa ttaaacagtg gaaaagagtc tatagtattt
    88021 gaagatgtgc caattggaac aactgtcgga gaattaattg aaagagctgg tggaataaaa
    88081 ggtgaatatg gtgaaataat cctaggagga cctttcactg gtaaagctac tactttagat
    88141 gctccaataa ctaaaactag tggtggtata atagttacta tgccatttgt taatgaaaag
    88201 agaaaaatgg gtcttttagt ctgtgcatgt ggacctaatg aagagagaat gagagatata
    88261 gcaactaaaa tgggagttac tgatatagta tcagttcaaa aatgtaaaca agctcaagaa
    88321 attaaaggtg cattaaaatg tgaaaatcca ggacactgtc caggacaagc tcaaaaatgt
    88381 attgaattta agaaagctgg agcagaagtt atattaatag gaaactgtac tgactgtagt
    88441 aacacagtaa tgggttctgc accaaaatta aagttaggtg tatatcatat tactgaccat
    88501 gtaatgagaa cagttaatca cccattaata agaagaataa aaggtgacgt aagattaaaa
    88561 ataaaataat agataaatag aagttagaca tctttagaag taaaacttaa aaattacttc
    88621 taaggatgtt ttttaatgta ttttgagggc aatatatagc tttaaaagaa atcaaaaaag
    88681 tgccaaatgt aaaactaatt aaaccatata tatttaagaa gggattgaat tggagttgtg
    88741 aattatgtta gtagaaacca ttctaagtgt ttgttattgg tacatttgat atttgtatgt
    88801 aaatacagaa aaaacttttt gctcagatgg atactttgct ttcagtgtag gaaatgtttc
    88861 taaagaaatg attgaaaaat acatacaaag taagggatag gtttacatcc accaacctaa
    88921 aggtatagtg gttttacgcc ttaatttata aaaagaaatt aatttatatt attattaagt
    88981 ttaaaataaa aagtctcaaa ttgatttata agtcattttg ggactttttt atgtaaatat
    89041 aatatgcaaa tatagtttgt ttaaaaatat ctattttaat tatattctta aatttatgat
    89101 tggatacagg cattcattaa ttgtttgatg aatagaaaaa tgttttgaag gtgaaaatag
    89161 tattgaaaaa ataatatact aagggtataa ttcatttgat ttcatttgta taaatttaat
    89221 tataaatttt aaagtgatta tataaattta aatgctaatt acttaataaa ttttaataat
    89281 aattatttaa taaataatta ttataatatg ctagaataaa tatatataaa taagttttga
    89341 tgaggtacta ctataaaggg ggggacttta tgttttcgat accagaagta aaaaaagtag
    89401 aagaggtaat ggatacaaaa tttacaacta tagacgaaga cacaagaatt gaagatgcaa
    89461 taaaagaaat gataaaaagc aacacaaaaa ctctaatggt aatagattca tctgaccaat
    89521 taaaaggcat tatatccatg acggatatac ataatcttta tgagatgcat aaaaagtatg
    89581 aaggtcaacc agtaaaactt ataatgaaga aggatgtaat atatgtcaac gaaggtttaa
    89641 ccttagatga atgtagagat ataatgatat taaaaaatat agggattctt cctgttctta
    89701 gagataataa aattattgga gttctaaaac aagagcacat tagggactat ctatatatgc
    89761 atttagaaga ttatggattg actttgaagt atattatagg tcaaattaaa gaaggaattt
    89821 gtgctataaa taacgaaggt gttgttatct tgtggaataa gtttatggag gaaaggtatg
    89881 atataaagtc tgaagatata gttggtcgac cgatgaatga atttttggaa aatactattt
    89941 cagaaaaagt actaaatagt aaagttggaa tgagtgactt gtattttaca gataaaaaag
    90001 aaaatatgta tgcattagtt catgcaaatc ctatatttta taaagaagaa tttatcggtg
    90061 ttgtatgtac agaagttgat gttacagaag ctaagatatt agctcttgaa cttgaaaaag
    90121 taaatgatac attaaaatat ctaaagaacg aagtcaaaaa tttatctaaa ggtagttttg
    90181 ataagatttt aggtaaaagt tataaattgg aaaaatcgaa agcgattgca aaacaagtgg
    90241 ctagaacaaa tagtagcata tttatttggg gtgaaagtgg tacgggtaaa gaagtatttg
    90301 caagagctat tcatgattat agtgagagaa aaggtcaatt tatacctgtt aactgtagtg
    90361 ccataccaaa tgagttattt gaaagtgagt tttttgggta tgaatcaggt gcatttacag
    90421 gagcaagtaa aaagggtcga ataggtatat ttgaacttgc aaaagatgga actgtatttt
    90481 tagatgaaat tgccgattta cctcttagta tgcaagcaaa gttgcttaga gtattacagg
    90541 aaaaagaaat aagaagagtt ggtggagata ccacaataaa aataaatcct agaataatat
    90601 cagctaccaa taaagatttg agtaaaatgg taaaggcaga aaaatttaga gaagatttat
    90661 actatagatt aaatgttgtt gaaataaaga ttcctccact tagagagaga aaagaagaca
    90721 taggattatt ggttcatagc tttttagagg agatatgtaa acaaaataat aagcctgttc
    90781 ttacaattag caaagatgta atagatatat ttcagaatta tagatggaaa ggtaatatta
    90841 gagaattaaa aaatacgatt gaaaatattg ttgtattgtc acaaaattct aaaatagatg
    90901 tagatgatgt accaagttat atgatggatt ctacaaataa tagtactgaa gaagaagagt
    90961 atcccttaga tttaacgaag gcaactcaaa aaattgaaat aaagaatata accaaggcac
    91021 ttaaaatgtc taatggaaat aaagctaaag cagctaagat attaaatata cccagaacaa
    91081 ctttgtatta taagatagac caatacaaaa tagatgtgtc taaaatatga catatgacta
    91141 aattttgaca aaatgataaa ctttaattta aaacctagta aagccaacac ttgtataagt
    91201 gttgtgtata tagatgtgtt aaaaaaaatg aaaaagtgtt gattaattga cacttttttt
    91261 gtttgagaaa atgtttacaa atacaaaaaa taacatattt taaataaata tttatataat
    91321 atttggctaa aaatagcgat agatgaagaa tctattatag aaaaaatctt tttgttaata
    91381 agttggcata ggaattgctt ataatataaa gtgactttga gtgagaaaaa aataatatta
    91441 atcataacaa attatgtagg ttttaattta cttaatttct cagttaaggg gttacctgtt
    91501 gaggaattga gatttaaaat aataaataag aaaataatgt aaggaggtat tttatactat
    91561 gtcaataact ttagaaacag ctcaagccca tgcaaatgac ccagcagttt gttgttgtag
    91621 atttgaagcg ggaacaatta tagcgccaga aaacttagaa gatccagcaa tatttgcaga
    91681 cttagaggat tctggattat taacaatacc agaaaatgga ttaactatag gtcaagtact
    91741 aggagctaag ttaaaagaaa ctttagatgc actttctcca atgactacag ataacgtaga
    91801 aggatacaaa gcaggagagg ctaaagaaga agtagtagaa gaaacagtag aagaagcagc
    91861 tccagtatca gaagcagcag tagttccagt aagcacagga gttgcaggtg aaacagttaa
    91921 aatacacata ggtgaaggta agaacataag cttagagata cctttatcag tagctggtca
    91981 agcaggagtt gctgctccag tagcaaacgt tgctgctcca gtggcaagtg cagcagcaga
    92041 agtagctcca aaagttgaag aaaagaaact tttaagaagc ttaactaaaa aacactttaa
    92101 aatagataaa gttgaatttg ctgatgaaac taaaatagaa ggaactactt tatacatcag
    92161 aaacgcagaa gaaatatgta aagaagctaa tgaaactcaa gagttagttg tagatatgaa
    92221 gttagaaata ataactcctg ataaatatga aacttacagt gaagctgtat tagatataca
    92281 accaatcgct actaaagaag aaggcgaatt aggttcaggt ataactagag ttatagatgg
    92341 agctgtaatg gtattaactg gtacagatga agatggagtt caaataggtg aatttggttc
    92401 ttcagaaggt gagttaaata ctactataat gtggggtaga ccaggtgctg ctgacaaagg
    92461 tgaaatattc atcaaaggtc aagtaacaat aaaagcagga actaacatgg aaagaccagg
    92521 acctttagct gctcaccgtg catttgacta tgtaactcaa gaaataagag aagcattaaa
    92581 gaaagttgac aactctttag tagttgatga agaagtaata gagcaataca gaagagaagg
    92641 taaaaagaaa gttgttgtta taaaagaaat aatgggacaa ggtgcaatgc atgataacct
    92701 aatattacca gttgagccag ttggtacatt aggagctcaa ccaaacgttg acttaggaaa
    92761 catgccagtt gtattatctc cacttgaagt attagatggt ggtatccatg cattaacttg
    92821 tataggacct gcatcaaaag aaatgtcaag acattactgg agagagccat tagtaataag
    92881 agctatggaa gacgaagaaa tagatttagt aggtgttgta tttgttggtt ctccacaagt
    92941 aaatgctgag aaattctatg tatctaagag attaggtatg ttagttgaag ctatggaagt
    93001 tgatggagct gtagtaacta ctgaaggttt cggaaacaac catatagatt tcgcatctca
    93061 catagagcaa ataggtatga gaggtatacc agtagttggt gtaagtttct cagctgttca
    93121 aggtgctcta gttgttggta ataaatacat gactcacatg gtagacaaca ataagtctaa
    93181 gcaaggtata gagaatgaaa tattatctaa caacacttta gctccagaag atgctgttag
    93241 aataatggct atgcttaaaa atgctataga aggtgtagaa gttaaagctc ctgaaagaaa
    93301 atggaatcca aatgttaaat taaataacat agaagctata gaaaaagtta caggagaaaa
    93361 aatagtatta gaagagaatg agcaatctct accaatgagt aagaagagaa gagaaatata
    93421 cgaaaaagac gaaaactaaa atttagatac taactaagat ttagacaata acataaattt
    93481 agatccaagt ttaaaacagt atagagaggt agaattataa tggataggtt aaaatatatc
    93541 tcatcagaga ctttttatga aggtattata gttgacatca aaggtggtgg agtgactata
    93601 gacctaaaag gtagacttgg acaatttaaa atacctaata gaatgcttat aactgactac
    93661 gaacttaaga taggtcaaga agttggattc atgctaagct atcctgaggt attaagtcca
    93721 gagcctaatc aagagtatgt agaaaatatt aggagagaaa aagaaaaaca agcagaaatg
    93781 caatcaaaac aagaagaaaa ataataaata atcgtttgaa aatagaaggg agaggaaata
    93841 tatgagcctt acaacagtac aaggacttca atctgaaata ttcgttccaa taacacctcc
    93901 tccagtttgg actcctgtaa ctaaagaatt aaaagatatg actatagctt tagctacagc
    93961 agctggtgtt catttaaaat ctgacaagag atttaatcta gcaggagata ctacatttag
    94021 agctatacct aatacagcta cagttgatga aatgatggta tcacatggtg gatatgacaa
    94081 tggagatgta aacaaagata taaactgtat gttccctata gatagattac atgaattagc
    94141 tgcagaagga tttatcaaag gagtagctcc tatgcactat gcattcatgg gtggtggagg
    94201 aaaccaacat gtcttcactg aagaaactgg tcctgctatc gctgctaaac ttaaggaaga
    94261 gggagtagac ggtgtagtta tgacagctgg ctgaggtact tgccatagaa ctgccgtgat
    94321 cgtgcagaga gcaatagagg aagctggaat acctacaata ataatagcag ctcttcctcc
    94381 agtagttaga caaaacggaa ctcctagagc agttgctcca ttagttccaa tgggtgctaa
    94441 tgctggtgaa ccacataata tagaaatgca aacacatata ttaagagata cattagagca
    94501 attagttgca ataccatctg ctggtaagat agttccatta ccatacgaat ataaagctca
    94561 cgtttaaaat gtaatttata tttgaaaata tagaaccctt ctcctacacg gttaggagag
    94621 gggttttaag aacaaaggtg gatattatgg aagaaaaaat aatgagaaga cttgttataa
    94681 aaccgtttca tatgaatgaa gttaatttcg gttcaaaaac ttctataaag aaagatgtac
    94741 ttacaataga tttatcaagt atagatgaaa taaaagaaag agaagagtta ataacagaca
    94801 taaaagtaga cattataaaa cctggagatt atgatagaga aattaatact attatggaca
    94861 ttataccaat atcaacaaaa gttttaggca gactgggaga gggtatcaca catactttaa
    94921 cgggtgtata tgtaatgtta actggtgcag atgaagatgg aaatcaaatg catgaatttg
    94981 gttcttcaga aggaattttg aaagaccaaa tggtatttgg gagatatgga actccatcag
    95041 ttgaagatta tataatccat gtagatgtaa ctttaaaggg aggtttacct tttgaaagaa
    95101 cacttccact tgcagcattc agagcatgtg atgattttat acaagaaata agagcgtctt
    95161 tgaaaatgga agacggaaga aatgctactc aagttcgtga atattttgac aaaattcgac
    95221 caaatgcaaa aaaggttgtc atagtaaaac aaatagcagg tcaaggtgct atgtatgaca
    95281 atcagttatt ctcaaaggaa cctagtggat ttgaaggagg aacatcaatt atagatatgg
    95341 gaaatgtacc tatgattata tctcctaatg aatacagaga tggtgccctt agagctatga
    95401 cttaagagag gtggatatta tgggaatagg accttcaaca aaagaaacat ctcttcatca
    95461 ctttagagac ccacttttag acatagttga aagtgataag gatgtagatt tacttggagt
    95521 aatagtagta ggaactccag atggaaatga aaataaaacc tttgtgggac aaagaacggc
    95581 cgcttggctg gaagccatga gagtagatgg agctatagtt tcatcagatg gttggggaaa
    95641 ctcacatgtt gactacgcta acacatttga ggaaatagga aaaagagata tacctgtagt
    95701 tggagttaca tttaatggga ctcaagctaa gtttgttgta agcaatcaat atatggatac
    95761 catagttgat atgaacaaat caaaggaagg tattgagaca gaagtagttg gagaaaacaa
    95821 cacaaatgaa atagatgcta aaaaagcttt agcattttta aaacttaaaa tgagaaaaca
    95881 tggataaaaa atttaagtaa gggaatgagt tttgtgggaa tttctacatc aatgaaaaac
    95941 acatcacttc atatatttag agacccgtta ctagatttga tagataatga ttctgacata
    96001 gacttgttag gagtggttgt agttgggaca tcagagcaca atgaatggaa aacattttta
    96061 gcaactagac ttggaagatg gattgaatca ttgcgacctg atggagtgat tataacttta
    96121 gatatggcag gaaaccagca cattgatttt acaaatgcta tagcagagtt tgtaaaatca
    96181 gatatacctg cagtaggtct tactattatg ggagcagatg gattagtaat taccaatcca
    96241 tatttggata aagctaccat aattgattat aaaaagacaa caggctacat agaaacagaa
    96301 gtagttggag acaatcacat ggatgaagtt gatgttaaaa aagcattggc tttcctaaaa
    96361 ttaaaaatgc gtaaagacgc aaaataaacc taagggggaa tttgatatga aatttagcag
    96421 aagtatacaa gctatagact ctcatacagc aggtgaagca actagaatag ttgtaggtgg
    96481 aatacctaac ataaaaggaa attctatgcc tgagaaaaaa gaatatttag aggaaaatct
    96541 agattattta agaactgcta taatgttaga gccaagagga cataatgata tgtttggttc
    96601 tgtaatgact caaccttgtt gcccagatgc tgactttgga ataatcttca tggatggtgg
    96661 tggatacctt aacatgtgtg gccatggtac aataggagct atgacagcag ctatagaaac
    96721 aggtgtagtt ccagcagtag agcctgtaac tcatgtagtt atggaagctc cagcaggaat
    96781 aataagagga gacgttacag ttgtagatgg aaaagctaaa gaagtatcat tcttaaacgt
    96841 accagctttc ttatataaag aaggtgttga agttgactta ccaggtgttg ggactgttaa
    96901 atttgacata tcatttggtg gaagcttctt tgctataata catgcaagtc aattaggttt
    96961 aaaaatcgaa cctcaaaatg ctggtaaatt aactgaacta gctatgaaac ttagagatat
    97021 aataaatgag aaaatagaaa tacaacatcc aactttagct catataaaaa ctgtagactt
    97081 agttgaaata tatgatgagc caactcatcc agaagctact tacaaaaatg tagttatatt
    97141 tggtcaaggt caagttgaca gatctccatg tggaactgga acaagtgcta aattagctac
    97201 tttacatgct aaaggtgaat taaaagtagg agaaaaattc gtatatgaaa gtatattagg
    97261 aactttattc aaaggtgaaa tagttgaaga aactaaagtt gcagatttca atgctgtagt
    97321 acctaaaata actggttctg cttatataac tggatttaat cattttgtaa tagatgaaga
    97381 agacccactt aaacatggat ttattcttaa ataagtaata aataaattag gaaattaaaa
    97441 tagaatagta gccacttgtc ggttgctatt ctatagcttt taggctataa gattcagaat
    97501 atatgaaaaa ataaaaaaat aggaggatgg attatggtag caatcttaaa ggcattatat
    97561 gtagtattcg cagcaatctt tgcagttgtg tttggtaaag acgtagctaa agcaaacaaa
    97621 gaggggaaac tagaagaaca aagtactcca aaagttgctg taacaggatt tataacagac
    97681 ttctttgata cattaggaat agggtcattt gctccaacaa tagcaatgtc aaaggcttta
    97741 aagttaaata taccagataa aaaaatgcct ggtacattaa acgtagcaca tactattcca
    97801 gttgttacag aagcattcat atttacatca atcataccag ttgatggtgt tactttagta
    97861 tctatggttg tggcagcagc agttggttca tatataggtg caggaataat agctaagatg
    97921 gacgagagaa aaatacaact tgttatgggt gtaactttag cattaacagc aatattaatg
    97981 ttattaggtc atccttggat taacgtatta ccaggtggag gaaatgaatt aggtcttact
    98041 ggtgttaaat tggtaatagg tgtaataggt aactttatac taggagcttt aatgacagct
    98101 ggtataggtc tatatgctcc aggtatggca atggtttatt tcttaggaat gtctgcaaaa
    98161 gttgcattcc caatagttat gggttcttgt gcattattaa tgccagttgc aagtatgaaa
    98221 tttataaaag aagatgcata tactaaaaaa gcatcagtta taatagctat atgtggttta
    98281 ataggagttt tcgtagctgc atatatagta aaaactctac caatggatat attaaaagca
    98341 ttagtaatag tagttatagc ttatacttct gctacaatga taatggctgc aaataaaaac
    98401 aaaaagactg cttagttaaa gactacttag tgtttattaa atattacagc taataataaa
    98461 gattataaac tgctttaaaa tattgaatta atattttagg gcagtttttt atttgctaaa
    98521 ttaatataaa gcaattaaca tgccaattat gtaatatata tagtgattta gtagatttaa
    98581 tgtaaaaaac gttgtatttt caaagaataa agcataattt aaagctaaat atttaaattt
    98641 tataatcaat aagttcaata aatgttcata tattaataca gattaataaa aatataagct
    98701 gtaataagtc taatataact tataattaag aaaaataagt ttataatgac tcaatattca
    98761 tctgaattat ttgaataaat ttaattcgtt gaagttgctt atatagagtg aataaattta
    98821 agttatatat gacttattaa ttatataata ggatttttat aattaataca aaactgaaat
    98881 aggtagttta attagtatat gtagtacaaa aagataataa ttttataatt ataaaagtga
    98941 aatattaaat gaaatttata actaaataaa aacttttaaa cagcaatcaa agatttgtaa
    99001 taaaatacat cccttataaa tatatttatt atataagctg ataccagaaa tataagaatt
    99061 aacaattgtg gagggataaa atatgatagc tgttaaagat gagaataacg tagtaaactt
    99121 aagaggggag ttagacaata agctagaatt tagccatgag atatttggag aaaaatttta
    99181 taatatgaaa ataaaaataa acagactaag cgattctttt gatatacttc caatgactgt
    99241 atcagaaaga cttctccaag atattgacct tgataaacaa aatttagtca atgtcgtagg
    99301 ccaattaaga tcatataaca aaacattaaa taataaaaat agattagtgc ttacagtgtt
    99361 tgtcagagaa ataaaaagca tagacgagga aaataaagac cctaatagta tatttttaga
    99421 tggatatgta tgtaaggaac ctgtgtatag gaagacacct ttaggaaggg aaataaccga
    99481 tttattagtt gctataaaca gaccttataa taaatctgat tatataccat caatagtttg
    99541 gggtagaaat gctaaatttg caaagaatct aaaggttggt gatagaatac agctttgggg
    99601 tagggttcaa agtagagaat atgagaaaaa aatagatgaa aataatgtgg tcaaaaaaat
    99661 ggcatatgaa gtatccatat cgaaaataaa aaaattggat gaaaataaca atgaataaac
    99721 ataaaaaata gactgatttt tatgaataaa atcctaataa atttggtata atatcatatt
    99781 aaaatgtata aagattgttt aaaaaaatac taatgaaata tctcttgaat agttgctcgc
    99841 catttattat aatgtaatct gtacataatt tataattgag gaaatgaaga ggtgaagcat
    99901 tgtgaaaagc atattatgtc agataaataa acagccagtt aaagctaaat atacatctga
    99961 tgaattagaa tgttttttgg atacaattga gtataatgta ggtgataaaa tattgcttgt
   100021 tggtcatata ggaaacctag gcaagagatt gagaggtctt ggaacttctg taactatact
   100081 ggagaatagt aattatgaag atgtctgtta ttctctagtg tataatgaaa attgcaatgt
   100141 agttaaaggt aagttagagt ttctaccatt tgatgataat cagttcaaca agataataat
   100201 agttgaccaa tttaatgtta ttacagattg tgaaaaagct tcatctgaaa tacaaagagt
   100261 gttaaagggc aatggagagg ttatattaga ggatttaaat ttaaagaatt taaaagttaa
   100321 gttaaattat cttaaacata aattttgtgg ttctgttgca aagattcact atccacatga
   100381 agtatttaat atattttcaa gattaaactt tgatggtatg attaaagagt caaataaatt
   100441 aaaatatatt tatgtgggaa aaagaagata aatgagttaa aatataaata tggatataat
   100501 ataaaagact aggttaagcc tagtcttttg ttataaggag atgtttagat ggaaataaat
   100561 tatgagttaa taataattgt tatgctcttt gtaatcctga tgtcaatcca atttacttta
   100621 aataagatat acttgattct taaagaaata agacaaatac ttatgttaaa gaaaaataag
   100681 gaatgatggt tatgataggt ttagaatata taaaatctga tattcaaaat atagctgaag
   100741 ctatagtatc agtactcaat atagatgtaa ctatagtaaa taaggagtta tttaggattg
   100801 caggtacagg agtatatata gacaaaatag gtgagaaagt agataaatat acggctttta
   100861 aaaaatcact tacagaacag atcacaatac taattgatga cccaaagagt agtgatgtat
   100921 gtagggaatg ctataaaagt ggggcttgtg tagagtttgc agaggtgtgt tgtcctatta
   100981 tatgtgatgg cgattctcat ggcgttatag gccttatagc ctttacaaaa gaacaagcac
   101041 aaattataga aaataataaa agtggtctta taaacttttt aggcaaaatg gcagacttaa
   101101 tatctaataa attaaaagca caaattaaaa cttatgagct tgaattagaa aagaaaaaat
   101161 tagagacact attaaacaat atggacaaag ctgttgtgtc tattgatgtg gatggaaaaa
   101221 ttgataaata taattcaaaa tttaaagagc ttttcaatat aaaggatagt ataactggca
   101281 aaaacatatt tgtcgaatta gattttataa agaaaccttc tataaataac tttaagaaag
   101341 acaaatcgtg tagttttttt tataaaagat acggatatga ttcgaaggga atatacaaca
   101401 tcaataaaat agtattaaaa aatgagttaa agggatatgt tattgatttt atagataaaa
   101461 gagatgctat aaaaaactac aataagatga ataaagatta tagaataaaa ttggaaaaca
   101521 taattggaga aagtgtagct ataagaaatt ctaaaaagga agccctaata gcttctaaat
   101581 caacatcaac agtacttatt actggggaaa gtggaacggg taaggagcta tttgcaagag
   101641 ccatacacaa ccatagcaat agagtagata atccttttat agctgtaaac tgtgctgcta
   101701 taccagacaa tttattagag agtgaattat ttggatatga agagggagct tttactggag
   101761 ctaaaaaagg tggaaagctt ggaatgtttg aagtagctca taagggaagt atatttttag
   101821 atgaaatagg agatatgagt ttgcatttac agtcaaagtt attgagagta ttacaagaaa
   101881 aggaacttaa taaaattgga agtaaatcaa atgtctcaat agatgtaaga attattgctg
   101941 ctacaaataa agatttagaa aaaatggttc aaaatggcac ttttagagaa gatttatatt
   102001 atagattaaa tgttatacct ataaaattac caagtttaag agagagaaaa gaagatatcc
   102061 cacttataat caagcatatg gttaaagagt attcaaaaaa attagataaa aatgttattg
   102121 acatagatag cagggttgtt gatgctatga tggaatataa gtggccaggg aatataagag
   102181 agttgcagaa tattattgaa tatagtgtga atatgtcttc ttcttcaata atcacaatga
   102241 atgtaattcc tcaaaaaatt aagaatacct ctgtagaaga gttagaagtt aaaagcgata
   102301 ggataattcc acttgatgaa ctagagaaga ttgagataat aaaagcttta aataagtaca
   102361 aagattataa aaaagataaa gaattaacag ctaaagcact tggaatatca agagctacat
   102421 tatatagaaa aattgaaaaa tacaatataa tttcatagta atataataaa aagctatata
   102481 aaatttaaat ttttctaaat tcataacttt aaagaaagct ttaaacttat actataagtg
   102541 ttttgcataa tcttttttta tgaattaaaa aatggttttt ataagttaaa aaataacaca
   102601 tttgagccgt ctcaaaatga tatagaatct cattctgaga cttttttttg tctttttgcg
   102661 aaattgtcat atgtttctcc attttaaaga atataaatac tctatgtaaa taaaaaaaat
   102721 acataaatag aagcagtcat accaatggtt atagaatata agactaaaaa tataaaaaga
   102781 tataaaaaat atggcatgta ttttgctata aatatagata agaaattatt taattaatta
   102841 tttgagtact aaatctaaac ttaattggga ggtttatata taatgagaga tataagaaaa
   102901 gaattagtgg aaatgttaaa ggcagaagtt aaaccagcag tagggtgtac tgaaccagta
   102961 gccttagctc tagcatgtgc aaaggcaaag gaattattag gagaagaaat agttgaaaat
   103021 cgtatgttag ttagtcctag tatctacaaa aatggcatgt gcgtaggtat accaggtact
   103081 gaaagattag gattaaaaat tgcagcagct ctaggtatag taggtggcca ttctgaaaat
   103141 ggattaagtg tgttagaaac tctaacaaaa gaagaagtta aaatagctga ggattatatg
   103201 gataatactc cactatcaat aacacctgct gatacaagag agaaagtatt tatagaagtt
   103261 gtgttaaaag gaaaaaatca tattgctaaa gtgagaataa gaactaaaca tgataatttt
   103321 acgttcttag aaaaagatgg agaagtatta ttagacaatg aaccaaaagt atcagcttca
   103381 aatgatgcgg cagaaaaagc tgaaagttta atggatacag taactataca agaattaata
   103441 aaaaatgtag aagaaattga ttttaaagat atagaatttt tactagatgg agtaaaaatg
   103501 aatgaagaga tggctgaata tggattaaaa caaaaaactg gtattggtgt cggatatgga
   103561 attaaaaagt ctatagaaga aggtctttta ggtaatgatg ttataaatta tgcaatgatg
   103621 ttaactgctg gagcttcaga tgcaagaatg gcaggcgtaa aaatgcctgt tatgagttca
   103681 aatggaagtg gaaatcatgg attaacagca attcttccaa tcgttgctta taataaaaaa
   103741 ttcccacaat ctgatgaaaa actagcaaag gctttagcta tatctcatct agtaactggt
   103801 tatattaaga actatacagg aagattatct gctgtgtgtg gatgtggtgt tgctgcttct
   103861 actggagcaa ctgctggtat ctcttggctt atgaatggta ctgaaaagca aatagaagga
   103921 gctatagaaa atatgatagc tgacttaagt ggaatgatat gtgacggtgc gaaagctggt
   103981 tgtgcattaa aattatcttc tgcagcatct gcagctatac aaagtgctat aatagctaag
   104041 caagattgtt ttgtaccacc actaaatggt atagttggtt caagtgttga gcaaagtata
   104101 caaaacttag gtagagtaag tgacaaaggt atgtctataa cagatgagat aatcttaaat
   104161 gtaatgaatg atatgaataa agttgactag tactttataa tatgttttgt attatgaggt
   104221 ataacaaaaa tagcataaat aaatttaatt agtaccctct aataaaatat gattatgtat
   104281 aaatttatgt ataatagaaa aaacttgtta gtgcaagttt tttctttttt tgtctaaaat
   104341 atatagtatg taatttagtg tggatatatg aactacttaa aatataagat acattgttaa
   104401 taattgttga atgaacataa aaactcaata atattgacta atattgaata agagtattga
   104461 aaaagtgagc aatctcttat aaaattaaga aggattatta caattggagg tctttttatg
   104521 gatatagaaa caaaaaaatg ggaagtattg tattcagaag aaaaaattaa agataaatta
   104581 agggaattag gagcaattat agaaaaagat tataaagata aaaatcttat ggtagtttct
   104641 ctattaaaag gtagctttat attttgtgca gacttagtta gaaatataaa tttaccactt
   104701 agagttaatt ttatgactac atctagttat ggaaacaatg aagaaagtac tggaaaggtt
   104761 aaagtggttt cagatgtgac tactgatata gcaggatatg atgttttggt tgtagacgat
   104821 attactgatt ctgcacttac tatggatttt gtgttaaaac atctaaaagc taaaaatcct
   104881 gctagtttaa aatgctgtgt tcttttggat aaaccaagca gaagaaaagt tgatttagtg
   104941 ccagattatt gtggatttga aatagaagat aagtttgtgg ttggatatgg gtttgatttt
   105001 ggtgattatt atagaaatgt tccttatata ttcaatgtta ctgatgaaga tagataagca
   105061 attatataat tttgtggatg ccttaatatg atttttatta atcgtgttga ggttttttta
   105121 tttaaaaagt aattaaagta gtattaaatt aattttatgc aatttaatta tctatttttt
   105181 ataacataat aaaaaaattt taaataattg atgggaaatg agttttttaa ttgtattaat
   105241 aattgtaaaa gagtactaat aattgtaaaa gattttacaa aaaagtaatg aaatttaaga
   105301 atcaaagcat atatgttgat ataagcaaat agatacatta tcacataaga aattgtcgat
   105361 tcatataatt atatagagta atactcaata tttatagagt aatactctaa ctttaaaaaa
   105421 ggaggattaa ttatatgagt gatatttcag gtccaagttt atatcaagat gtaggtccaa
   105481 cagggccaac aggtgctact ggtccaacag gaccgacggg gcctagaggc gcaaccggag
   105541 cgaccggagc aaatggaata acaggaccaa caggaaatac gggagcaacc ggggcgaatg
   105601 gaataacagg accaacagga aatatgggag cgactggagc aaatggaaca acaggttcta
   105661 caggaccaac aggaaataca ggagcgactg gagcaaatgg aataacaggt ccaacaggag
   105721 caacaggagc aacgggagca a
//
LOCUS       DAMJWO010000219        20730 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.guided.077, whole genome shotgun sequence.
ACCESSION   DAMJWO010000219 DAMJWO010000000
VERSION     DAMJWO010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20730
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.guided.077"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            162..1760
                     /locus_tag="PC366_003844"
     CDS             162..1760
                     /locus_tag="PC366_003844"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HDF2579281.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDMDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILAVTDIIKEGSYLIYKAEDSLIANAFDVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
     gene            complement(1995..2186)
                     /locus_tag="PC366_003845"
     CDS             complement(1995..2186)
                     /locus_tag="PC366_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium protein"
                     /protein_id="HDF2579282.1"
                     /translation="MAGLTTEPGGGGVLSGYFAGFLFGGTTFTINNFSSTTVGIRNGQ
                     SAGTAATLTIFRIADTVMT"
     gene            complement(2355..2948)
                     /locus_tag="PC366_003846"
     CDS             complement(2355..2948)
                     /locus_tag="PC366_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HDF2579283.1"
                     /translation="MRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYY
                     NLRTITWNDRVSMENIRGYLPIGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNY
                     PYQIFEFTSSRDCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSIGPMG
                     ATGPTGATGNSSQPIANFLVNAPSPQTLNNGNAITGW"
     gene            complement(2949..3095)
                     /locus_tag="PC366_003847"
     CDS             complement(2949..3095)
                     /locus_tag="PC366_003847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium protein"
                     /protein_id="HDF2579284.1"
                     /translation="MRKIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFF"
     gene            complement(3773..4297)
                     /locus_tag="PC366_003848"
     CDS             complement(3773..4297)
                     /locus_tag="PC366_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDF2579285.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQIMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(4362..5114)
                     /locus_tag="PC366_003849"
     CDS             complement(4362..5114)
                     /locus_tag="PC366_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDF2579286.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDISKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(5145..6443)
                     /locus_tag="PC366_003850"
     CDS             complement(5145..6443)
                     /locus_tag="PC366_003850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HDF2579287.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEDIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMEDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQQGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREVNVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(6460..8724)
                     /locus_tag="PC366_003851"
     CDS             complement(6460..8724)
                     /locus_tag="PC366_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HDF2579288.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(8979..9797)
                     /locus_tag="PC366_003852"
     CDS             complement(8979..9797)
                     /locus_tag="PC366_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDF2579289.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGIDEKIIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIIL
                     LDEPTAGLDPVSTRSIVDIIKGLNKDNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFVNENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(9790..10488)
                     /gene="cbiQ"
                     /locus_tag="PC366_003853"
     CDS             complement(9790..10488)
                     /gene="cbiQ"
                     /locus_tag="PC366_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HDF2579290.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIKNIFVLSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEIFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKMHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(10491..10775)
                     /locus_tag="PC366_003854"
     CDS             complement(10491..10775)
                     /locus_tag="PC366_003854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HDF2579291.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPDYEPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGVQKGKRS"
     gene            complement(10765..11517)
                     /locus_tag="PC366_003855"
     CDS             complement(10765..11517)
                     /locus_tag="PC366_003855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HDF2579292.1"
                     /translation="MKQNIKLGVIAALMLIVLTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLVGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIISFLIFKALKKKDG
                     NNAMPVFLAAAIGDLATYTVTSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(11706..11898)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(12030..13802)
                     /locus_tag="PC366_003856"
     CDS             complement(12030..13802)
                     /locus_tag="PC366_003856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HDF2579293.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYNMDKHPALDSMTRRIVNDIRNIDTN
                     QDMMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(13816..14745)
                     /locus_tag="PC366_003857"
     CDS             complement(13816..14745)
                     /locus_tag="PC366_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDF2579294.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            14974..15162
                     /locus_tag="PC366_003858"
     CDS             14974..15162
                     /locus_tag="PC366_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDF2579295.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRAKRRKEVQYE"
     gene            15155..15856
                     /locus_tag="PC366_003859"
     CDS             15155..15856
                     /locus_tag="PC366_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2579296.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHCGAEGLHLLDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSINNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            15858..16781
                     /locus_tag="PC366_003860"
     CDS             15858..16781
                     /locus_tag="PC366_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2579297.1"
                     /translation="MNTSVYLLLILALSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            16938..17861
                     /locus_tag="PC366_003861"
     CDS             16938..17861
                     /locus_tag="PC366_003861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2579298.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGCEKRVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDHTLRLYNTTLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            17854..18591
                     /locus_tag="PC366_003862"
     CDS             17854..18591
                     /locus_tag="PC366_003862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2579299.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPTKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFASIALGRRK"
     gene            18602..19375
                     /locus_tag="PC366_003863"
     CDS             18602..19375
                     /locus_tag="PC366_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2579300.1"
                     /translation="MWKLLWAECQKIRRSKIVWITFFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETKLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            19391..19543
                     /locus_tag="PC366_003864"
     CDS             19391..19543
                     /locus_tag="PC366_003864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579301.1"
                     /translation="MKKIKKLIILIVFLFLFGMLHCYTEWKFNNDPPKGVIERINEWT
                     DKIGLD"
     gene            complement(19916..20524)
                     /locus_tag="PC366_003865"
     CDS             complement(19916..20524)
                     /locus_tag="PC366_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDF2579302.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
BASE COUNT         6829 a         3471 c         2626 g         7804 t
ORIGIN      
        1 taataatttt tatattaaat ttgtagtatt tatgtaagaa ataaatttta tataatattt
       61 tttcactaaa tttttttctt tttacaacaa atactcacta ccttttgata taatattttt
      121 atcaattatt attatattca agttttgaaa ggagtattaa aatgagttta ttagttttcg
      181 gacataaaaa tccagataca gattcaatat gttctgcaat ttcattagca catttaaaga
      241 acaaactagg aataaaagca acagcttatg ctttaggaga tatcagaaaa gaagctaaat
      301 atgccttgga ttactttaag gtagatgcac ctgaaatttt agataatgtt agaatacaag
      361 ttagagattt aaattatgat aaagtagtac ctttaacacc aacttcatct atattagagg
      421 cttataacct tatggatgaa aaaaatgtta aaacactacc tgtaacttat gatgatggaa
      481 cttttgctgg tatcattact atgaaagaaa tagctaaaaa tctacttcat caacacttta
      541 caactataca cacatcacta tcaaacattt gtaaaaacct taatggtact attcttgtgg
      601 actgtggtga agatataaaa ggtagagtag tcactttatc atttggaatg gagactctaa
      661 tagagacttt aaaagaagga gacatagcta ttgttggaga tagatatgat agtattgaat
      721 atgctattga tacaaaagtt aaacttttaa tacttactaa tcatacagag atttcaaaag
      781 atttgctagc tcttgctaag ataaatggag tgtctgttgt ttctgttgaa agtgacaatt
      841 ataaaacttc taatgtaata aatcaatgta gtttcttaga ctctatagaa gctacagaaa
      901 atttaattac attcaaagaa gatgattata tggatgaaat aaaagagatt atgctagaaa
      961 caaacttcag atcttatcca atattagatg atgataataa gtttttaggt ttagtttcaa
     1021 aaggtcatct attaaaccca tctaaaaaga atgttgtttt agttgaccat aacgaatatg
     1081 ctcaaagtgc tgatggaatt gaacaagcaa acatagttga aataattgac catcataaac
     1141 ttggtggtat ttctactgat gttcctatgt catttagagt tatgcctgtt ggatgcaata
     1201 gtactataat ttatcaaatg tacaaagaaa acaatgttga gataccttat gaaatagctg
     1261 ggcttctttt atctgctata ttatcagata cattattatt taagtctcca acaacaactg
     1321 atatggataa gaaagcttgt gaagaattaa gtaaaatagc aaaagtagac atggaaaaat
     1381 acgctatgga tatgtttaaa tgcggtactt ctttagatga atatactata gaagaaatag
     1441 taaatatgga ttttaaagaa tttaatatga gtggacatag agttggtatt ggacaagtat
     1501 ttaccttaga catagactct atatttgcta aaaaagatga gtttttatct tatataaatt
     1561 cgactgatta tgacaaacta attcttgcgg ttacagatat aatcaaagaa ggttcttatt
     1621 taatctataa agcagaagat agcttaattg ctaacgcatt tgatgttgaa ggtgttcaag
     1681 gtacatttgc accaggtgtt gtatcaagaa aaaaacaatt agtccctaat ttaactactg
     1741 caatcaaaaa ttttaaataa tataaaattt ttaaataacg aaaactgtct caaatctata
     1801 tttgagacag ttttttatta tacatatatt gataataaag ttaaataaaa atccataaat
     1861 ttaaaatttt tatgaatata ttttattatt attgttattt tattcattct aaaataggta
     1921 aaactcaata tataaaaata cttttgtcat ttaaataaaa cctaaatagt ttttaagatt
     1981 attttagaca cgttttaagt cataacagta tcagctattc taaatatcgt caaagtagcc
     2041 gcagttcctg ctgattgccc atttcgtatc cctactgttg tagatgaaaa attatttatt
     2101 gtaaaagtag tccccccaaa taaaaaacca gcaaaatatc cagaaagtac tcctccgcct
     2161 cctggctcag tagtaagccc tgccaaatct tttcctccta aaattgggaa taggatagca
     2221 aaagaatatt gatttatact tgatgaacct ggttgtaatg ctactgaaac tgatatataa
     2281 tacacaccat tttcttgtac tgtaaacgta ccatttgcat ctactgttat acttgaacta
     2341 tttcctatta ttgtttacca acctgttata gcatttccat tatttagtgt ttgtggagat
     2401 ggtgcattta cgaggaagtt agcaattggc tgagaggaat tgcctgttgc tcctgttgga
     2461 cctgttgctc ccattggtcc tatacttcct gtcgctcctc ttggtcccat tggacctgta
     2521 attctaattg gaagacactc acatttagga taacaattat ctataattct atcttcaaat
     2581 gttacaagta tatacggttt gttacaatcc ctactagatg taaattcaaa aatctgataa
     2641 gggtaattta aagataaagc taacccataa ttaggatatt tattcattgc ccatgctttt
     2701 atagttcccg taatatttaa acaaatatag ttggatgtat cacttatccc aattggtaaa
     2761 tatcccctga tattttccat agacactcta tcattccatg ttatagttcg taaattataa
     2821 tattcactta ttcttttaat ttcaatatct actttttctt taaaaatatg attcttattt
     2881 gaatcaatat gaataaataa ctctgctttt aatatacttt tgtcttttaa tatatctggt
     2941 attctcactt aaaaaaaagt aatcaacttt tcttttacaa aactatttga acatttactt
     3001 cctattaagc aataatctaa attactaaag tttttatctg gatatttttt agatataaaa
     3061 gtatcatcat ttaaataaag tataattttt ctcatttata atccctccat tttgggtcta
     3121 tatcatacta tgtttaaaat acatgcttag ttacaataca attaaaattt atagtattaa
     3181 atttttatat aataatgctg atttctacaa aaaaagaaca tgtcattaga aacttctaat
     3241 agcatgttct ttttcattat tatatattac actttaaatt attccttgac tggcttagct
     3301 ggtgtaaact aaaccagtct ttctaaaata ttaagcactt ttttcttatt atgtttttta
     3361 ggatttattg tctctattat tgtaaaccaa agttataaaa ttgtaaatag aatatattac
     3421 cataacaata tttttttata agtaaaaatt ataaaaaacc ttatttttat taaatagaat
     3481 aaataaaata agtttaaaaa atactgaaat aagtgttttc cacatatttt atatatttat
     3541 ttaatacatt attatttaaa aataaatata taaacaatca taataaaatt tttttaataa
     3601 aactttattt tttagttaaa atcatacaat atatagcttt ccacaataca aataaattaa
     3661 aaagtgaaat gtatttgtct aaaaacataa taacatttca ctttatcctc atttttaagt
     3721 aatatatatt tttaattttt atttataact caatctagtt tttatataag ttttagtttt
     3781 tttctacatc tgagtaatct attccaaaag tttctacagt aacagacttc ataatttgtg
     3841 gagtttgtgg cttatcagct gaatctgttc taactgatgc tatttcatca actgtatcca
     3901 taccttctat cactctacca aaacctgcat actgaccatc taagtgtggt gagtttttat
     3961 gcattatgaa aaattgagaa ccagctgaat taggtgccat agttctagcc attgatatga
     4021 ctcctctttc atgttttaaa ttgttagtaa atccattacc actaaattca ccttttattg
     4081 agtgacctgg gccacccatt cctgtaccat ttgggcatcc tccttgtatc ataaatcctg
     4141 gtattactct atgaaatatt attccattgt aatatccttc atttactaat gatacaaagt
     4201 ttttaactgt atttggagct atatttggat ataactcaat tttgatttct tttccatttt
     4261 ccatttctat agttactata ggatttttat tttccataat ttattacctt ccttttcatt
     4321 agttaaatta cataattaca tttattatat tatactctaa attaaagtct atcaagtata
     4381 ttttttccta tttcgtatcc ttcttgataa atagttttac aaaactcatc atcaaagtta
     4441 agcgtatctt taggagcaaa ttgagtatta ggtctaacta ctattatttt atcttcatca
     4501 tatacttttt taatatcctc tggcaactca taattatatt ttgtggatat taaaataatt
     4561 ttatccacat tatccccaat taatggttca attaatgcac tcctaattaa acctccatct
     4621 aatttgaaac catcataaat tccttcttgc acatctttca caaattgttc tttaaatcca
     4681 agagttgcgt ttggatttga tggtaacaac ccactgtatg aaatgctgat aatggcttca
     4741 ttacgaggca tttttgatat gtcaacaatc ttttctgata ctactttatt atcaacttca
     4801 acataattaa cataaaagtt catttcttct atattactat catctagttc ccttaggttg
     4861 tctatagcag gagaattatc cacagtatta tttactattt ttacatttcc attctggata
     4921 tcttttatat ttgtccacat tttctccaag ttatcaacat tccctgtgta caaataatat
     4981 ccatttattg ctcctattga tgtccctgaa atcgaataaa atttatttat tcctccatca
     5041 tacaaggctt taactactcc tgcttgataa gccccttttg ctcctccacc ttctaaacat
     5101 aatcctaatt tcatagtctc atctccaaat tgtttatctt atatttatat ttcaaaaaac
     5161 ttactaaatg ttttatatat actatagtgg tcctcaacat ttcctaattc tcttatagag
     5221 tgcattgcta aaattggact tcccacatcc acagatggta tatctatatg agtagaagat
     5281 attggaccta tagtacttcc tcctctttca tctgacctat taacaaattc ttgatactca
     5341 acattaactt ctctacatat atttttataa atagctatag aatatccatc actagtatat
     5401 gcctgactag catttatctt tataactgga ccttttccca ttattggttt attagttggg
     5461 tcatgctttt ctggaatgtt tggatgaata gcatgagcta aatctgatga tatcataaaa
     5521 gatgaataaa tagactcaaa gaatccctct ctatccttac ccattgatat gcaaattctc
     5581 tccaatatat ttaacaacat gtttgaatct gcaccttgtt tagtagagct accaacttct
     5641 tcattgtcaa atacagccat tacatttaca ccttgttgac ctttagtatt aacaagagca
     5701 ttcaaactag catgtaccat tgcaagatta tcttgtctcc caatagatat aaattcatca
     5761 ttagccccta ttaaacttcc tttttcaaat tcatataaaa ataaatcaaa atctataata
     5821 tcttccatat ttacatctaa gttagatgct atttgcttta taagaaaatt atctttttct
     5881 aatgtatcat ttaacatccc aactaaaggt aacatatctt tttgcttatt atatgaatga
     5941 ccatcattta tacttctatt taaatgtatt gctagatttg gtattataca aattggcttt
     6001 ttaaagtcta taagcctttc atttggtttt aatatactat caccttttaa aactactcta
     6061 ccagctatcc caagaggtct atccaaccat gtacttaata ttgctcctcc atagcattct
     6121 gtatttaact tcaaataaga tttttcagct tctatttctg catttggttt aatactaaat
     6181 gtaggagaat ctgaatgaga gcctattatt ctaaatccat ctctttctat atcttctgaa
     6241 tttactacaa aagctactat agctgataga ttcttagtaa cataatactt tccaccaact
     6301 cttagattcc atctttgatt caaaactaat tcttcaaatc catttttatc taagatttcc
     6361 ttagtactct cgactgcatg aaaagacgac ggactatcat atatgaagtc tattaagttt
     6421 ttagcaaagt ttatactatc cattcctcat ttacctccat tataaaatat ttagtgttgt
     6481 atattcttta tttatttttt taattccctg ttggtcaaaa gctatagtaa catctgtacc
     6541 aattatagaa accactgtcc caaccccaaa tttaggatga tgtaccttag aaccaagttt
     6601 tatatcatct ggattagttt ctttattaga atcttttatt gtagcattaa ctttatctgc
     6661 aactttagat ttgcttatag tactcatata ctttttagta tatttatcta acatattata
     6721 acttgcttta gaatagctta gttctttttt tactttgtac aatctttcta tacattcttc
     6781 tggcagttct tccataaatc ttgaagctat tgcaacattt gttttaccat ataatgttct
     6841 cttctctgtc aatgacatat atagctcttc tttagctcta gttataccaa cataacaaag
     6901 tcttctctct tcttctattt gtgaatcact catagatttt atagctcttg atataggaaa
     6961 taacccttct tccatacctg ttaaaaacac aacagggaac tctaaacctt tggatgtatg
     7021 aattgtcata agcgaaaccc tatcattgtc ttcttcatca tttgattcag atgtaagtgc
     7081 tatacttgtt aggaatgtct ctaagtcttt attttcataa gtatcatcat tactactttc
     7141 aaactccaaa gctatagaaa taaattctct caaattatca attctgtctt gagcttcttc
     7201 acctttgcct gttaaatctt tttcattttt atttcttatc tctacaagct cgtccatata
     7261 tcctgtagta tccaagactt tttctataag tttgctaaca ggataaactt cttttatagt
     7321 tctaagagtc cctataatat caacaaatcc acttatactt gcccttgcct tagtagatat
     7381 atctgaattt gtttctatat caattaatac tgagtatata ctttcctgtt ttaagttagc
     7441 tctatcttca attttttcta tagttctaag ccctatacct cttctaggaa catttataat
     7501 cctttttata gatatatcat cttgtggatt ttgaataact cttaaatacg ccaacaaatc
     7561 ctttatttct tttctctcgt agaattttgt accaccatat atattgtatg gaatttgact
     7621 tctatttaaa gcgtcctcta caggtcttgc ctgtgcattt gctctataaa gtactgcaaa
     7681 atccttataa ggtctatttt cttttctagc tatttgtgca attgaatcag caatgaaatc
     7741 agcctcttct atttcgctac cagttaattg tatctttata agttctcctt cttttttttc
     7801 actccaaagc ttttttcttt ttctttctat attattagat ataactttat tagctgcatc
     7861 taatatcact tgtgtagacc tataattttg ttctaacttt acaacatgta cattgtcata
     7921 atctttctca aattcaagta tgtttcttat atctgcgcct ctccatccat aaatactttg
     7981 gtcatcatct ccaacaacac aaatattttg atgttctctt gctaataatt ttatcaattc
     8041 atattgagct ttacttgtat cttggtactc atctaccatt atgtatctaa atctacttct
     8101 gtaatatgct aatacttcat cattagcctt gaaaagttct acagttttaa gtattaaatc
     8161 atcaaagtca agtgcactat ttctttttaa acggtcttga tataacgcat aaatatctgc
     8221 aatcttaacc attctattat ctgccatgtt gatatcttta aactgctttg gagtataaag
     8281 tttgtctttt gctcctgaaa ttgcacttat aactgctttt ggttcaaaca ctttatcact
     8341 taaatttaat tcttttagac agtctttaac caatgtaact tggtctgctg aatcataaat
     8401 tacaaaactt ctattgtaac caatcttatt tatatctttt cttagtatac gaacacagca
     8461 agaatggaat gtacttatcc acatatcctt agtttcagga cctatatttt gttcaactct
     8521 ctctctcatt tcatttgcag ctttgtttgt aaatgttata gctaatatat ttggtgcttg
     8581 tacaccttta tcttctataa gatatgctat tcttgttgtt aataccttag ttttacctga
     8641 accagcacca gccagtataa gtactggacc ttcagtcttt tctactgctt ctctttgagc
     8701 aggatttaat gtatctaaat tcatatttct cctcctgtta acagccataa atatatttta
     8761 atctaaaata tgaattactt caaattataa ttatgtatta tattaataga ttatttccaa
     8821 tatattacaa ttaaataaca tttttccata taatttattt aattgtttaa taaaaaaaat
     8881 aaccttatga tttggggaat cataaggcac ctttaagggg tctaggttaa gggttattat
     8941 atataaatct atttttttaa aataggttta gggcttaatt atttatttgt attaagttct
     9001 ctttccttcc aatacttata caaatcttct tctttcttaa ataagggtaa attcatattt
     9061 ctatgtactt ttactaacca tggggattct aggccagctt gtataatgtt attttcattt
     9121 acaaatacat tttctgcctt tccttcatca attaaaatcc ccttatccaa tacatatata
     9181 taatcgcata tttcatacat taaattcata tcatgactgg atattactat ttttatatta
     9241 tctttattca atccctttat tatatctaca atagacctag tacttactgg gtctaaacca
     9301 gctgtaggct catcaagcaa tataatttca ttttccattg ctataactga tgctatcgct
     9361 accctttttt tctgaccata acttaaaaaa tgtactggtc tatctataaa atctattcca
     9421 ttaacagcta ctagagcttt gtttattctc tctttaatta ttttttcatc tataccaata
     9481 tttctcattg caaaggctat atcatcatat acttttgaat aaaaaatttg tttttctggg
     9541 tcttggaaca caatacctac attttttcta aggttgtata aacttctctt atcatatttt
     9601 aacttttctt ctttaaaaag aatttctcca gatgtaggct ttaatatacc cattaaattc
     9661 ataaataatg ttgattttcc tgaaccattt gaacctatta tacctataac atttcccttt
     9721 gaaaaatcca tattaatatt taatagtgca ttggtattct tttcatattg ataagttaaa
     9781 ttatttattt taaacatcat tatcccctac tatgtgaaat ttaccatcat acaattttat
     9841 gtctaatgat atacacatat catcatacct tgtcataagt cttttgtaca gcatactgcc
     9901 aagaattcct aatgatttat atgaagtttt taaatttatg tacccaaatc ttagttcttg
     9961 tgacttatat atttctgaaa attcttctaa aaatatgaat ataaacctat atattaacat
    10021 tgatagctca acaaaagtat caggcaaatg cattttttta aagaagaata ttaattgatt
    10081 aaaaggtgtt gtaagtatac aaaagtatac acaagtcaaa caagacatag ctctaaataa
    10141 cacatgaata gacatgtcaa tagatgcttt tgatattcct acattgaaac taaaaatttc
    10201 aaaactatat aataagtctg ccttattaaa agatatattt acaagagtta ttcctatact
    10261 aagaaataaa aagtacattg gtattctgag taattttaaa taattcttta aatctattcc
    10321 agctacacaa acaactagaa tactcattaa aatcataatt ccacttaaaa caaatatatt
    10381 ttttattacc atagaagcaa tcagaaagat tactcctatg gctacttttt tatttggatt
    10441 tactttactt aatctatttg tatatgcata tttatcaatt ataagcataa ttaacttctc
    10501 tttccttttt gaacacctaa tatgtaccct attacaccag cacctaacgc tgcttgtgca
    10561 gagaataata aactttctat ttctccactt ggtggctcat atgggctact aaaccatggt
    10621 tcataatctg gatttatctt agtaatttca ctctcagctt gaccatctgc tcctccatat
    10681 tcagctcccg aattaacaag taatgggaat atgataagag ctactactaa taaaagtagt
    10741 aatatattag ttttcgtctt tgttttagca ctcattagct ttaactcctt tatcattatt
    10801 ttctagtatg cttttttctc cattttctgt aattaaatta tatacaatta cagtaagaat
    10861 accctctgct attgctattg gtatttgagt cataaagaaa attcctaaaa acttaattgc
    10921 tgaagccatc actccacctg atgggtctgg gaaagccagt gctaactgta tcgaagttac
    10981 tgtatatgta gccaaatctc ctattgctgc tgcaagaaat actggcattg cattatttcc
    11041 gtcttttttc tttaatgctt taaatattaa gaatgatata attggtccta taatagccat
    11101 tgaaaaagca ttagctccta aagtagttat tcctccatgt gccaatagta atgcttggaa
    11161 tattagaact atagttccaa gaacaaacat tacacttggt ccaaacatta ttgctccaag
    11221 acctactcca gtaggatgtg aacaacttcc tgttactgaa ggtatcttta gtgctgacaa
    11281 tacaaataca aatgctccac acagcgctaa taatactttc tttttagggt cttgctttac
    11341 tatttttcct attgatttta gtcctactaa aaaaaatggt ataaatataa ctccccatgc
    11401 tatagaccat tttactggta agtatccttc cattatgtgc attgcattcg atgtaactgg
    11461 agttaaaacg attaacataa gtgcagctat aacccctaat ttgatatttt gtttcatttt
    11521 actatcccct ctctcccttt ctaataatta aaatataaat aatatatgtc tgatttattt
    11581 taaaaataaa aataaaaaag cctaactcga tggctaggct tctaattttc gataatccaa
    11641 atacaaacac ataaaatgaa catatctgta taattattat aagaaacttt ctccatcccc
    11701 gaagaaatta ctttaatatt ttaggcaggt ctcctgactt agcttcttcc tactcctctt
    11761 ccttcccatg agatataaaa aatatcatca tagtggctaa caaaagtttc gtctgcatca
    11821 cagtagcggg ggctgtaaag gaatttaacc tttttcccta ttaatcttgc ttaaagaacc
    11881 tataatatta tatatttaat ttttaaatta ttcttaaatc attttctata taaatcattg
    11941 tatacctttt ctgtgaaaat ttctacattt tttataaatt ttattcattt ttatattttt
    12001 atgtatataa attctttttt gtaagtttat taatttctaa ttatcttctt taaatacatt
    12061 gaaactacat cagaaaatct agttatatct cttgaatata taaaatcatt tccatatatt
    12121 aatctttcag cttcaagttc tgattctttt cctgtaaata ctcctagtac taatatattt
    12181 tgctttctag cttttctcac ttcattggct gtatctctca aaccaactat acccctataa
    12241 gccttttctc ctcttaatgt tctctcacta ctttttccta tctttacatc atttggtctt
    12301 ccatcgctga gaactatcag gattttattt tcttcatctc tatttattag accactacat
    12361 atagatttta ttgccaaacc atctctatta ttaccagcac aaaaatattc aaatatattt
    12421 tcactatttt ttatactatc atcataatct ttaaatcttt ttaatattgt atagtctaaa
    12481 aaactagaaa atcccatcac tctatttggt atgccaactt ctgttagagc atttgcaatt
    12541 atgtaagctt gaattgccac atttccctga tttctacttt gagagccact tgcatccaat
    12601 aatatatcaa taacgtattt ccctttttca ttttctatat ctttataaaa tattttatta
    12661 ttattacttc taccaactct ccaagctcta tttgctaata tagtaccaca atcagaatat
    12721 actctacttt tagcattttc ttctattaaa attcttgaca gactttcttt taatctcttt
    12781 atttgctgtc tatacattct agcatgttct ctaaattttc ctaaattatt ttctttttgt
    12841 cttgttacat attttagttg aaatacatta ttacactcac ttctaagaac tccatctgta
    12901 aagtgtattc tacaaccttc atgaacattt ctacaatttt gtgtctcaat ttttttaatt
    12961 tcacctttac tcaaataagt ttttccataa taatgttcta tttttgaata tatcttattt
    13021 gcagtgtctt catcaacata tataactcgg tctgctgaat tgctacattt agaatcatca
    13081 aaatccccta caccttctac aagcatggat gaagatattg aatctatatc actttcaata
    13141 atattttctt cttcatcact ataaagttct tcatacatga aatcagcaaa tgtatcaaaa
    13201 tttacttcta cactttctac attattttca tcaataagac tattttcttc tccatttaat
    13261 atgtattcga aataagttaa atatataaca tctaatgctt ttaaaatctc catcatatct
    13321 tgattggtat ctatatttct tatatcatta actattcttc tagtcatact atctaatgct
    13381 gggtgcttgt ccatattata aagtacaaat gtgtatttaa ttttatccat aatattatca
    13441 ttgtgtattt tggtaaaacg tgaaacaata tctttataag catttcttct tatgtcttct
    13501 atccctggcc tatctttaat gaccttttct tcaactattg tatttaatat aacttgaatt
    13561 agacccagta taatatcttt gttgtatcct tttcttattc tatttgtaag atatttttta
    13621 actatatccc aatctacata ctttcttcta gcacctgcaa ttattgcaaa atatagacct
    13681 atttcttttg aagagtaatc tttttctgat atatctatac tttcattgta atcaccagct
    13741 attgtccatg ataagttatt agctctattt tcaaattcat aatcatcata tatccatttc
    13801 ataatctcac ctatattaaa tatgacttat tggaaataca tctatactct cccatttatt
    13861 aggtattcta gttttaatta catctccaac catttctttc tcatatacat caaaagtctt
    13921 tcctgtaagt cccatattaa ttgcaagagt tggttttaat cctcttctta tagtcttaag
    13981 agatgccata agaccacgta aatcaatagc tttactagat atctctccat tttgagactt
    14041 caattgtaaa tctaaaaata ttcctgcaaa gtgtattaat ttttcttcat cagcatctga
    14101 aaattcattt tttaaaatca tcattaactt atcttcttct ataggaggaa tatctattac
    14161 cataaatcta gataccagtg cttcattaag ttcttttgtt cctgcatatt cataattcat
    14221 agtcccaata aatcttgttg ctggatgtag attgactctc tcatacccag gtacatcaat
    14281 tattcttcta tagtctaaag ctgaatgtac cacaactata gcatcatttt ttgccatatt
    14341 aatttcatca aatactccaa aacctccatt aatagcacac tcataaactg agcctcttct
    14401 aagtttaact tcattgtcta taaatgtatc tgtacctata agtgttgaac tgtctgtatt
    14461 tatatgaaat gatgtattcc actgaggtct attaaatatt tcccctagat tatcagcaag
    14521 taaatttttt cccgttgcct ttggtcccga taataatata ttttcttctt ctaaaatagc
    14581 tgctatacac atagacaaga tatctttacc ataaaaataa gttttagact ttgttactct
    14641 gtattctaaa tctttttcta aaccataata atttctaaaa tacagtacat cttcaataag
    14701 tttttcatct accccttgca cccttagatt atctattata tccatatttt tacccctttt
    14761 atataaatag tatttgtttc atttcttatc accattttag cataaaagga tataagctaa
    14821 aattgatttt ttaatctccc ccattttaag taaaaccatg caccatttta tcactacaaa
    14881 attaagagta ctacttactg atatttcttg attttgttcg tctatacgta tataatatat
    14941 gctgataaat tatgaggaaa ggatgattga aatatggaat atatgtcttg cccagaagta
    15001 gcaaaaaaat ggggcatttc tgaaagaaga gtacaaaaac tatgtgaaga aagtcgcata
    15061 ccaggagttt caaaactcgg gtatatgtgg ctgataccaa agaacgcaga aaagcctgtt
    15121 gatggtagag cgaaaagaag aaaggaagta caatatgaat agcgttttga ttatagatga
    15181 tgacaaagaa ctttgtgctc ttatgaaaaa atgtgttgag caagaaaatt tatctgctat
    15241 tactgcacat tgtggtgcag aaggtctaca tttgctcgat aaaaatagac acacactctc
    15301 tcttgtaatt ttagacataa tgatgccaga tatagacggt tttcaagttc tgaaaaaaat
    15361 tagagaaaca agtaatattc cagtaattat gcttactgct aaaaatgacg aggatgataa
    15421 agtttccgga ctacgtttag gtgctgacga ttacctaaca aaaccgttca gcataaacga
    15481 acttatggct cgtgtcaatt ctcttattcg tcggtatact atgttaaacc ctgcttttat
    15541 aacagacaca gattgcataa taataaatgg catgattatt gacaagacaa accgaattgt
    15601 ttctatcaat aatattcctg ttcaacttac aagcaaagaa tttgatttac ttgcttttct
    15661 ggcttctaat aagggacggg tatttaccaa aaaacagatt tatacacaag tatgggaaga
    15721 agaatatgct tttgacgata gtaacatcat gtctttcatc agtaaattga gaaaaaagat
    15781 tgaaccagac cccaaccatc cattttatat tttgacagtt cgtggtgtcg gttatcgttt
    15841 taataaggag gcttaacatg aatacaagtg tctatctact tttgatattg gctcttagcc
    15901 tgattattat agcgtacctt gtttctgtcc tgctacgtgt ccgaatacaa cttacactta
    15961 taaaagatgc tttagaggat ataaaaaatg gaaaccttaa tcgccgtatt ttaacagatg
    16021 aaaacgacat tacaaaacaa atttgctatg atattaacga aatagcaatc aatagccaat
    16081 ttcaacttat tcagcaaaaa caatcagaac aagcctacaa acagctaatg acaagtctct
    16141 cccatgatgt aaaaactcca cttgcttctt tggtcggtta tttggaagca gtagaaagta
    16201 aaattgttgt aggagaggaa aaagacgagt atatccatgt tgcgtctaat aaggctcatt
    16261 acttaaagaa ttttgtagaa aatctatttg aatgggtaaa attggattct aaggaacaag
    16321 tttttcattt tgatattttt gacttgaatg aattatcccg taatattata tctgattgga
    16381 tacctgtttt agaaagcagt cattttgaat atgaatttga tataccagaa atagagtact
    16441 tcttacgtat agacgcaaat gcatataccc gtatcattaa taacctatta caaaatatta
    16501 ttacccatag tagtggcaac aaaatgacat tgagaatttt tgaaaacaaa gagcaagctc
    16561 aaattataat aacagataat gggaaaggta tatcttcaga caatctccca catatttttg
    16621 aaaggttgta ccaatgcgac cattcacgag cttcaaaggg aaatggttta ggcttggcga
    16681 ttgcaaagga acttattaac gctcataagg gaaatattac cgccaacagc actcccggta
    16741 tgggaacaga atttacaata ttgcttccta aagccctgta aaagtacgag gctttcttac
    16801 tctaaaacaa gataaaagca agattatggc aaggttttgg caaggttcat gttttataat
    16861 tctaattgta gttgattttg acgttgtatc aactatcttt tgtagaaaca aatttattaa
    16921 aagtgaggaa attatatatg aatgattttg tgattgaaac aaagcaactt acaaaaattt
    16981 atgggaatca aacagtagtt gacaaagtca atctccatgt aaaaaaaggc cgaatatatg
    17041 gtctgttagg acgcaacgga gctgggaaaa ccacaattat gaaaatgatt ttaggattga
    17101 cttcaatcac gtatggcgag gtagatgtat ttggagagaa tattaaggga tgtgaaaaac
    17161 gagtatatcc ccgtatcggt gcaattatcg aaacgccagg attttatcct aatctgacag
    17221 gaacggagaa cttggagatt tttgcaaaac ttcgtggtac agccgcccct aattctgtaa
    17281 aaagagcatt ggagattgta ggcttacctt ataaaaataa aaagctgttt agtaaatatt
    17341 cacttggcat gaaacagcga cttggtattg ccaacgctat cctgcatgac ccggaactgt
    17401 tagttttaga tgagccaacc aatggacttg accctattgg tattgcggag atgagaaagt
    17461 ttattaggga cttgagcgtt gagcatggaa agacaattct tatctccagt catattcttt
    17521 cagaaatctc attgttggct gatgatattg gaattatcga ccacggtgtt cttttggaag
    17581 aaagtagtat gagtgaacta gaaaagaaaa acagtaaata tatcctgcta caagtttcag
    17641 atattccaaa gacatcactt attttagagc gtcaatttaa cacgaaggat tattccgttc
    17701 aagatgacca cactttacgc ctttataaca ctactctgga tatgggtgaa atcaataaag
    17761 cacttgtaat gcagaatgta actgttatta gttctcaact ttgtaatgat actttagagg
    17821 actactttaa aaaaatcaca ggaggagagg gcattgctta aacttattca aacagaattt
    17881 cttaaactgc gtcgtaggaa acttatttgg ctgatgttgt tgtctgctct cattatgccg
    17941 tttttcgcac tactatactt caattatttt ggtaaaacag gtgttgagcc aacaaagttt
    18001 tataaatggt ctgcatttgg ttatacactt tggattattt tgcccgttgt tttgggtata
    18061 ttttgcacca tgcttataca cgaagaaaac cagtatgata tgctcaaaca gctttggatt
    18121 gtacctatta gtaaaatggg atactttttt agtaaatttt tcgttgtttt gatttactct
    18181 atttgtttta tgctgattac agccgttgct tctgtgttat ttagtgtact ttctggatat
    18241 gtcgtattta gctgggcaag cattttatat ttgttgaaaa aatgtttaga aattggtgta
    18301 atcactgctt ttgtaatgtt gccgattttg gcaatcgcta catctcaaaa aggatacatt
    18361 ctcccaattt gtatcacatt ggtatatgcc ttttccggtt ttgttataat gacaataaat
    18421 atgtatttac acccattatc cagtatggga gttattatca tgagaaataa agacattcca
    18481 ggtcttatat tttcacagga aattaatgtc ccattagcat ttctttgtat ttgtatttgg
    18541 agtattgtat cagtattgtt tgcaagcatt gcactaggaa gaagaaagtg aggtgtagat
    18601 aatgtggaaa ttactttggg ctgaatgtca aaaaattcgt cgttcaaaaa ttgtttggat
    18661 tacatttttt gcatccatta tgatagcagt catagttttt gcaggagggc aggatgtata
    18721 taatgaccca gatttacatt atggcttaaa gagcgtttat gacggttcac ggtatataga
    18781 caatgcaggt tggtatatgg acgcggtaca accttggtca actttttttg ttcttcctgc
    18841 tgtcattgcc ctattaggaa gctatattat ttgtcgtgaa gaagaggagg acactattaa
    18901 atccctgcgt cttattccca taaatgaaac aaaattaacc atagcaaaaa tgattattac
    18961 ttttatattc agtatacttc tttatttgtt actctttact ataacatttt tgactgaatc
    19021 cgttttacat ttttccgatt tatcgacaaa actggtttta agttgcatga aagagtattt
    19081 tcttgatggc ataggtgtat tctttgcaat ttctcccatt attgccttgg tatcgcgcat
    19141 gaaaaaagga tattggcttg cattagtatt cacagaagtt tattctattg ctggactatt
    19201 tgcgggtatg tcaaatgtct tacaaacctt ttttcctatt gcagcaatat ttaatatttc
    19261 tggatactat ataactactg gagaaaaaat tatggggagt atcataagtt tattactttg
    19321 tgcctgcctt tctgcattta tactgaaagg gctaaaacac aatgaaaaaa attgaaatag
    19381 gtatatcaaa atgaaaaaga taaaaaaact gattattcta attgtattct tgtttctttt
    19441 tggcatgtta cactgttata ctgaatggaa attcaacaat gacccaccta aaggggtaat
    19501 agaaagaata aatgagtgga ctgataagat tggactggat tagtaactta tgttaattat
    19561 agtgaatgta atattagcaa gttattgttt cgtattttaa tactataact ttaaatattt
    19621 ggttttaatc ttccgaacga atataaaaaa actgtcacag aggcaacata tttttgaata
    19681 tttataaagt ggtagttttg attttcaaag ctgccgcctt ttcttctata taagcaaact
    19741 tatcctcaac aaagtgtaaa acatggtaca ttttaagaaa aaagtaccac agacacaagc
    19801 aataaaagaa acgccgagaa cctacaaaaa cgtagtgctt atgcagattt acgacgcctt
    19861 ctattttctc aaccgtctta atgaccttgt acaaaagaaa tttttctaat attttttata
    19921 atcttatctt gtgatgtttt ttatgtataa atgacttaat aacaaatcca ataaaaatta
    19981 tggatattgg tataattaga acgaggaatt tataatcatt ataatgtgac attattctta
    20041 cccaactctc agaaaaaata tatcctatac tgattaatga agtattccat atggttattc
    20101 ccacgataga tgatattaca aaagttataa tattttgacc tgctatacct gctataaaag
    20161 atatgtatgt tctacataaa gggattaatc tacatacaca aacagaaata gaagagtatt
    20221 tattaaaata atcttgagat gcaaatattc ctttctttgc ctttggacat atctctatta
    20281 ttttatttat gatagattta cctccccaat ttcccactgt ataacaaaat atcgaaccaa
    20341 gtatacctgc aattatactt aaaattaaaa ttgtcagaaa tccaaaatga tttcttgcag
    20401 caattgctcc acataaaggt aaaacaactt cgctaggtaa tggaaaacaa gcatactcaa
    20461 tcataattaa tacaaataca gagattaatc catattgtaa aataaaacta ttgattacag
    20521 acacttactt atctatctcc tttcttattt aaaggtttta agggtacata ttctaaggat
    20581 tctcacccta tatttaaaga atcaatctct ttaaactatt atatgtattt acacaaagca
    20641 tttataacat actttaaaaa tagtacctta aaataagaaa cttaataaat aaaaaaagat
    20701 tacgtggcta cgtcctactc tcccaggcag
//
LOCUS       DAMJWO010000220        16327 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.guided.091, whole genome shotgun sequence.
ACCESSION   DAMJWO010000220 DAMJWO010000000
VERSION     DAMJWO010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16327
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.guided.091"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            complement(116..808)
                     /locus_tag="PC366_003866"
     CDS             complement(116..808)
                     /locus_tag="PC366_003866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDF2579303.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMMAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(834..2021)
                     /locus_tag="PC366_003867"
     CDS             complement(834..2021)
                     /locus_tag="PC366_003867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDF2579304.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRIPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSISYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            2357..4234
                     /locus_tag="PC366_003868"
     CDS             2357..4234
                     /locus_tag="PC366_003868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDF2579305.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKTVYDEVIKIVPQSNDVGKKNESQEKQSIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSFIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            4546..5952
                     /locus_tag="PC366_003869"
     CDS             4546..5952
                     /locus_tag="PC366_003869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDF2579306.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLDFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNTVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            5980..6828
                     /locus_tag="PC366_003870"
     CDS             5980..6828
                     /locus_tag="PC366_003870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDF2579307.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            7489..8181
                     /locus_tag="PC366_003871"
     CDS             7489..8181
                     /locus_tag="PC366_003871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2579308.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            8178..9113
                     /locus_tag="PC366_003872"
     CDS             8178..9113
                     /locus_tag="PC366_003872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2579309.1"
                     /translation="MKMDEQTIILFLFLLSIGLLFLSIFAFSKLGHIHKRLKDIEEIL
                     ADVQIGNENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIGQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVDDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQISVESEIGKYTVFTVSLPLI"
     gene            9261..10184
                     /locus_tag="PC366_003873"
     CDS             9261..10184
                     /locus_tag="PC366_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2579310.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRKFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAHAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            10168..10938
                     /locus_tag="PC366_003874"
     CDS             10168..10938
                     /locus_tag="PC366_003874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2579311.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVPKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVTVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPLLSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            10948..11730
                     /locus_tag="PC366_003875"
     CDS             10948..11730
                     /locus_tag="PC366_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2579312.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGIAVLLSLFSFLCTFILGLLFCNINISVTLIVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            12107..12643
                     /locus_tag="PC366_003876"
     CDS             12107..12643
                     /locus_tag="PC366_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HDF2579313.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            12675..13064
                     /locus_tag="PC366_003877"
     CDS             12675..13064
                     /locus_tag="PC366_003877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDF2579314.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            13101..13487
                     /locus_tag="PC366_003878"
     CDS             13101..13487
                     /locus_tag="PC366_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HDF2579315.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGSQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            13614..15056
                     /locus_tag="PC366_003879"
     CDS             13614..15056
                     /locus_tag="PC366_003879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDF2579316.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVENESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLIDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            15353..16168
                     /locus_tag="PC366_003880"
     CDS             15353..16168
                     /locus_tag="PC366_003880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDF2579317.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINNFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKRVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEIRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
BASE COUNT         5905 a         2026 c         2983 g         5413 t
ORIGIN      
        1 tgaaatgatg aaaatatatt tgatttcata caaaaaagag tgcctcataa ctaaaaagtt
       61 cactttgaga cactccattt ttatatgtta gttgcattta aggtaaaata gaagtttaat
      121 catgttgaaa taactgaatt acatcttcta aatgattgta cattgatgta taacctaagt
      181 aagagtcttt actatcaaat gccatcatta tcttgttatg gtggctaatc atatccttaa
      241 gagaatttct atatttaaaa ccgaagtatt ggttagaaga aactgtttta ggtattaact
      301 cataatattt tataaaaatt ggattatgag aagctaaaat tatctctttg tgaaattgta
      361 agtcagcatc ataacattct tctatcaaac catgagaaac cttatccaat tcctctattg
      421 actttaggta agtatatttt attttttgaa gttctttaga tgtagcattt aaaattgcta
      481 gtttagtagc ttcactttcg ataagttgtc ttgctcttaa agattctaca taaaattctt
      541 gtatgttatg atttttatag atttcaccat catcaaatag gtcaactttt ttaaatcctt
      601 caactatagg acttgagtaa ggcacagctc taagtattcc ttccttacag agtatattta
      661 tggcatttct tacaggtatt ctacttatgt taaataggtc agcaatcttt ctctcacttg
      721 gtaatttact attaatttta aaagttccat ttagaatgtt taatttaata taatcaataa
      781 ttttttcagt ggcatttaag cttttcataa aaactcctaa acatataatt tttttatgat
      841 tgtattatat catagttaag agttaaatct acttttttat aatatgtata agacaggata
      901 gaggccaaaa tagctataat agccaagata aagtatccat attgtattga agtatattcc
      961 gatattttac caactatcat tggaaataca gacattccta tagcataaat tgcttgaaaa
     1021 aaacccattg cagtagattt ctgatgtttt ggtacatttt tcatagactc gctagtaagg
     1081 taagaaagga gtatacctgt agatatacct ggtagcactt gtagtacaaa tattatatta
     1141 atatttttta ttgttggaac taaaaagcaa taggctgaaa ctaaaataaa aactaaagga
     1201 atccaaaatt ttggcccata cttagtacaa aatttagtag aagcaaagcc agaagaagca
     1261 acagcacaca ccatgtaaga tatagaagat agacctatga gggtagaact agaacctaag
     1321 tttttaagaa tttgagtagt aaatgacatt gttgtagaca tttgaatacc ctgttgaatt
     1381 aatgccataa aggaaaaaaa tacaagtctt ttatctttgc agatagataa atatttttta
     1441 attgatattt tttcaggtat tttttttgaa ttatgatttt ttatatttaa ggctagaatc
     1501 gttccaataa ctgaagacaa tacactcatg atacataagg ctgtcattcc taatttttca
     1561 taaaataaag tactcataac aaatccaatc aacattccta gattgtttac caatattatc
     1621 gtactcgtag ctttttgttg atgttctgta gaaaaaaagt tggtatagtg aaccatgtaa
     1681 gaaatccaag ttgatgatga tattccagat aaaatgttag ctataagaaa accattgcct
     1741 ccaggagaaa agactcttat aagagatgct aaaccagcaa agaaaattcc agacagtata
     1801 aatattttat gtttatttat agaatcagca aatactccaa caggaatcct taataaacat
     1861 tgtgagattc catatgcacc tattattata ccaatcatat ttgtagatac attacatgca
     1921 cttaaatatg gattttggaa aggtatatat acatattgtg aaaaccagaa aaatgtaaca
     1981 atagaaagta aaagtaattt ttgattagat atttttttca tattatcctc catatggtat
     2041 ttttataatg caaataatat accatttaga ttttttaatc aagtactttc tctattaaaa
     2101 aaaatttaaa tatataatta ttatttacaa aaaaattata ctttatagtt gaattaagaa
     2161 aacgcttatg atactataaa gttaacaaat ttgaatatat aacagtagac gtgttactgg
     2221 taatgcaggc aagatcgaat caatttttat agattatcta tagagtacta tgggtataat
     2281 ctatttattt ggttcgattt ttttgtttaa ttggccataa aacaaaaagc ctatagttga
     2341 aaatggagga ttttttatgg attataaaaa tatagctcaa gaaattctac taaatgtagg
     2401 aggaaaagag aatgtaaatg aagtgactca ttgtatgaca agacttagat ttaaagtcaa
     2461 aagcgcttct aaagtgaata aggataaatt atctaaaact gaaggagtaa taactgttgt
     2521 tgagagtatg ggtcaaatac aagttgtaat tggaaataaa gtaaaaacag tatatgatga
     2581 ggttataaaa attgtacctc aatcaaatga cgtaggtaaa aagaatgaaa gtcaagaaaa
     2641 gcaaagtata attaattcta tattatcagc agtagctggt atatttacac ctacaatacc
     2701 tgctatagca ggggttggta tgattaaagg tattttatca gttcttgcta tgtattatat
     2761 gaataaaaat ggagtagata taaaagaaac gcaaagttat attatcttaa atgccatggc
     2821 cgattctata ttctatttta tgcctattat actaggatat actgcggcta aagtatttaa
     2881 tgcaaataaa ataatatcta tggtattagg agctacactt tgttatccaa cttttactgc
     2941 tttgatggca ggtgaagaat ctgttagatt tttaggattg gcagtaacaa aagctacgta
     3001 tacatcatct gttattccaa taattattgc tatatgggct ctttcatacg ttgaaaaagt
     3061 attagaaaag tatatacctg aggtaattaa aataataatg gttccaactt tatcattggt
     3121 tgtaatgtta cctgcaacat tatttttatt tggaccaatc ggaatttata taggaaatgt
     3181 cataaacttt tcttataagt atatttatga attaagccca gcgttgtgtg gagcatttgt
     3241 aggtgggtta tggtgtgtgt tggttatatt tggtgctcat agagcattat taccaatagg
     3301 tataagtgat gttgctcaaa caggaagaca gaatttattg gcatttgcag gagctgcaaa
     3361 cttttcacaa gcaggggctg ctctaggagt attctttaaa actaaaaatc aaggactaaa
     3421 aacaatttct atgtctgcaa ctataacagc tttatttggt ataactgaac ctgcaatata
     3481 cggtgccaat cttagattaa aaaaacctat ggtatgtgcc gtaatatgtg gtgcatttgg
     3541 aggtgcgata atgggaatgg gtggagctta tggtaatgca tttgcaaacc aaggtgtttt
     3601 aactatacct gtatatgctg aagcaggtgc attaggtttc ttaagttatc taggtggttg
     3661 tgctatagca ttttttggtt cagctatttc aacttatcta gttggatttg aagatttgga
     3721 agagtcttct aataaggaaa attcatttat aaaagtagaa acgaaggatg gtgttattga
     3781 tataacttca cctgtagagg gcgaatgtat agaattgtca gaagtaaagg atgatgtatt
     3841 tgcttcaaaa gctatgggag aaggtatagc tgtgttacct acaaaaggag taataacagc
     3901 ccctactgat tgtgaagtag cttctttatt tccaacatta catgcaatag gattaaaatt
     3961 agataatgga gcagaaatgt taatacatgt tggaatcaat acagtagagt taaatggtaa
     4021 atactttaca aaacatgtta atcaaggaga tttagtgaaa aaaggtgata aacttatatc
     4081 gtttgatata gataaaataa aaaaggctgg ttatgatgta actacgccag ttatagtaaa
     4141 caatacattt gattttgggc aagtagtttc ttgtaaatct agttatgttt caaccaatga
     4201 taatataatt tcattagtat tagctggtaa ttaagttaat ttgactagag ataagtaaat
     4261 tgatttaaaa ggaaataagt aaatcaacaa ttaaatacat ctaaaagtaa gtttattgca
     4321 atgaattgtt aaagaaaata attaatatgg agtaaagcta ttgcaatgaa gtaacaaaga
     4381 aaataattaa tatagagtaa gtttattgta atgaattgtt aaagaaaata attaatatag
     4441 ggtaaatcta tctcaatgaa ataacaaaga aaagagttaa tatagagtga acttattgca
     4501 atgaatcaac aaaaaaaata atcaatataa aaaggagaaa tatttatgaa tacaggattt
     4561 ccaaaagact ttttatgggg agcatcatct tctgcatttc aagtggaagg agcttgggat
     4621 aaagacaata aaggaaaaac cgtagccgac tataattctt ttaaaaagtc tcatttacag
     4681 gcagatacta aagttgcatc agacttttac cataattatg aagaagatat tgaattaatg
     4741 aaagaattag ggatgaaaac atatcgtttt tcaatttcat gggcaaggat aataccagat
     4801 ggtgaaggag agataaacca gaaaggttta gacttttata ataagataat agacaaacta
     4861 atagagtgtg atattgagcc attcgtaact ttataccatt ttgaccttcc atttaaatta
     4921 gtagagaaat ataatggttg ggaaagtaga gaaactgtct atgcttttga aagatttgct
     4981 aaaatatgct ttaagcattt tggagatagg gtaaagtatt ggcaacctca taatgaacag
     5041 aatttaattg ttagagtgga ggagagaatt aatatatatg atgaaacaga ttcatggaag
     5101 atagataaaa tgcgtgctca gatggattat aatctttgct tagcacatgc attagcagtc
     5161 aatgcatgtc atgagatgat aaaagaaagt aaaattggag cagcagtatc atcatctgta
     5221 acatatcctc ttacttctaa gccagaagat gtatatgcag ctagaatgaa tgataatttt
     5281 aaagtgtact atatgcttga tatgcatcat tatggagaat atccagggta ttatatgaag
     5341 tatcttgaaa aaagaaatac agttcctcac atggaagatg gggataaaga gatacttaaa
     5401 aaagctaaaa tggattttat agctgtaaat tattatagga caaattgtgc agaagcttta
     5461 cctgaagatt cacaacatcc atttggatta agagaaggaa ctgttgattt tagtatgtat
     5521 ggactattta aaatgtcaat gaatcctaac ttagaggctt ctgagtatgg agcagcaata
     5581 gacccatcag gtcttagagt tgccttaaat gaatattggc aaagatatca cttacctgtt
     5641 ataataacag aaaatggtct aggagctaaa gatatattag aagatggaaa aattcatgat
     5701 gactatcgta tagactattt aagaagtcat ataaatgcat gtaaactagc tattgaagat
     5761 ggtgtagaga tgattggata ttgtccatgg tcatttacag accttttaag ttcttctcaa
     5821 ggttttaata agcgttatgg acttgtttat ataaatagaa ctgaccatga agttttagat
     5881 ttaaaaagaa tcaagaaaga tagtttttac tggtataaag aagttataga gaacaatgga
     5941 atagtaaaat aaacataaat atatattgag ggttttagta tgtacattac aaaggtatta
     6001 aataattcgt tgctacttgc aaaggatgat aatgatgaag aaataatatt gatggggaaa
     6061 ggcattggcc ataattataa ggccgggtct gagttaaata aaaaagatat agaaaagatt
     6121 tttgttcttc atgatgaaaa tataaaaaag agtattatac aattggcaac agaaatagat
     6181 gcagaatatt ttggtatagc tcaaatgata attgcatatg gaatagaaaa atataactta
     6241 aaacttatga accatatata tttggcctta actgaccaca ttgcctttgc agtgagacgc
     6301 tttaaagaag gtataatgat tgaaaatcac tatttgttcg aaatcaagga atttaatcca
     6361 aaagagtatg atataggaaa atatgctatt actgttttta aggaggttct tggtttagac
     6421 ctaccagaag aagagattgg taatatagca ggccatttta taaatgcaca acaagataat
     6481 ccttatagtg atagaaataa gagaagtgct aaaattgtaa atgctatttt gcaaatagtt
     6541 cattatcact tttctattgt atataataaa gagtcatttt attataggag atttgtaatg
     6601 catctaaagg ccttttcaca aagatttctg gctaatgaac catcaagaga aaaaatagat
     6661 tttatatatg agcaagttca aaaaaattgt aaggaagagt atgaatgtgt gaaaaaggta
     6721 ggagcttata tgtataagga atactccaga gaattaccaa gacaagagga gttatatttg
     6781 atgattcata ttcataagat tttaggagaa ttatgcgaaa atagttagaa tatcttaata
     6841 tgctagtaat attataaaaa attaaaaatt aactacactt taaatatgaa caattgcatt
     6901 acttaagggg gttgtcttaa aattgatttt tttaattaaa tttgaagctc aactcctttt
     6961 ttaaaccttt atatcattac aactttaatg tttatacgcc tgtactttag atgtatatct
     7021 actttttaca tttctcaaca tgcaaaccta ccattttttg cagtatgtta attgaaataa
     7081 accattgagt taaccctaaa tttattctgg acttatagga atagttccaa agatacttta
     7141 aaatattttc tggaataatt gcttatttca catatgtttt attgtgatgt tttgatttaa
     7201 taaattcttc aactctgtat atagtaaatg tattatcatg tttgttttat tcaagcacac
     7261 ttataatacg cttgattttt tcacaatgat gaaatatact aatgggtgtt ataggtataa
     7321 gaatcgaatt acacttgaag aagtaagtga taaatgagat ataaatcctc atatgataaa
     7381 ctactatttc attgaggaac atattctaag tgatgtcaag atactacaat atgactaaat
     7441 tcctagtgat aaaaaagtct acgaatgagt gtagaaaggg gaactaagat gaataaagtt
     7501 ttaattatag atgatgataa agatctttgt attttgttaa aaaagagtat ttcaattgaa
     7561 cagattgaag caaactattg ccattctggg agagatggac tggttgaact ttcaaaacaa
     7621 gattatcagt tagtagttct agacgtgatg atgccaggta tggatggttt tgaaactatg
     7681 gaacaaatac gaaaatatag cagtattccc atcttaatgc tgacatcaaa aagcgataat
     7741 tacagcaaag tgcatggatt gcgagctggt gcagatgact atctaaccaa accatttgaa
     7801 attacagaat ttactgctcg tgtactgtct ttaatccgac gttacacccg ttttaatcca
     7861 aaaaatgagg aaccacagca actttctttc aaaggtttgt tgattgacct tgaccagcat
     7921 acagtgacta ccaatggcga acctatgttg cttccaccca aggaatttgg tgtgcttctt
     7981 tactgtgcaa ggcatcaggg taagattttg acaaaacagc agatttatga agctgtgtgg
     8041 ggtgagccat atgtatatga tgacagcaat atcatggcta ttatcagtcg cctaagaaaa
     8101 aaaattgaac tagacccatc atctcccatc tatttgcaaa caataaaagg aattgggtat
     8161 caattcaaca cggaggtatg aaaatggatg aacaaacgat aattcttttc ttattcttgc
     8221 tgtcgattgg tctacttttt ctttccatat ttgctttttc caagcttggg catattcaca
     8281 aacgcctaaa agatatagag gagatactgg ctgatgtaca aattggaaac gaaaatcgca
     8341 aaatactaat taagccatgt gatgttatgg ctccattggt ttatcagctt aatgagattg
     8401 tctacgatta tgaaaataag ttactttctc tgaaaaagtc ggataaagct agcaaacaac
     8461 ttatgacaag tctatctcat gatgttcgta caccattaac aactctgatt ggttatctgg
     8521 atgctgtaca cagtggtata gttatcggac aagaacggga ggaatacctt gaaatcgcta
     8581 ggcgtagagc ctacgacctc aaggattaca ttgatgttct ttttgactgg tttcggttga
     8641 actctgatga atttacgctg tcaatagaat ctgtggaaat tgcagagttg tcacgcaata
     8701 ttttgaaaga ctggattcct atattccatg aaaagaaact gaattttgaa attgatattc
     8761 cagaaaatcg actaatggta aatctcgacc cagatggata ttcccgtgtg gttaataatc
     8821 tggttcaaaa tgttcttgct cacagtaagg ctcggcaaat caagattacc atgagtgagg
     8881 attccagaat ggtattactc cgtgttgatg atgatggtgt tgggattgcc agagaaaatt
     8941 taccacatat ttttgagcga ctgtataagt gtgataaagg acgttcagaa aaaggaagtg
     9001 gtcttggtct atctattgtc agtcaaatgg tggagcgaat gggtggtcag atttccgtag
     9061 aaagtgagat tggaaagtat accgtattta cagtgagctt accattaata taaaattgtt
     9121 tttcccccat gtgacatgta tacacagggg gattttttgt aagttataaa gttgcaaggt
     9181 taatacaagg ttgttgcaag gttaatgtaa gattgaggtg gtatgatagc tttaataaac
     9241 aaaggaggat tttattattt atgaataatt taattattga aacaaaaaat ctcactaagc
     9301 aatatggtgc tcaaaagagc gtttctaatt tgaatattca cgttcagaaa ggtcgcattt
     9361 acggattgct aggaagaaac ggtgcgggta agacgacaac tatgaaaatg ttattgggtc
     9421 taacaaaacc aactactgga gaaattaaaa tatttggtca ggacattcac aataacgaga
     9481 agaagcttct tcctcgaatt ggatgtttga ttgaatcacc agggttttat cctaatctga
     9541 caggaacaga aaatctcaaa atctttgcaa ggcttagagg aataccaaaa aaaaatgcag
     9601 tagaatcagc actggatgta gtcggtttgc caaacaatga caaaaagtta ttttctcaat
     9661 actctcttgg tatgaaacag aggttggcga ttgctcttgc cattatgcat gacccacaac
     9721 tgttgatttt ggacgagcct atcaatggac ttgatcctat tggtattgca gaagtaagaa
     9781 agtttattcg tgatctctgc acagaacgag gtaaaactat tttgatttcc agtcacattc
     9841 tttctgaaat tgccttgttg gcagatgaca ttggtattat tgaccatggt attttgttgg
     9901 aggaagaaag tcttgcccaa ttagaagaaa aaaacagtaa atacatacat tttgctgtat
     9961 ctgatgcagc acatgcagca aggcttctgg aaacccaact taacctgaaa aatttcaaag
    10021 tagcagataa ttacaatatt atgctatatg atacagatgt ttctgttgca gaaataaatc
    10081 gtgctttcat tctaaacaac attgaggtat cagaatctca tttatgcgaa gatactcttg
    10141 aagattactt caagaaagta acagggggtg aaggaattgc ttgatataat ttcatgtgaa
    10201 ttttcaaaac tcaagcggtt aaaatttata ctgatttcta ttttaggtgc ttgcttattt
    10261 ccaattcccg caacaatttt gattgcaaag gacaacttgc cctttgagca attgttcaaa
    10321 ttagttgtca attttggata ttttttgcta ttaccaattg tattaagtat tgttgctagc
    10381 caactatttt ttatagaaag agataacgat gtattaaaaa atcttgcaac agtgccagtg
    10441 ccaaaaggaa aactggctct ggcaaaattg gctgtgttgc tgtttatatc attgttctac
    10501 tccgttgcag ggttaggagc tactatcatt ggaggtttca ttgttggaat agtagagggg
    10561 gttactgtaa aattaggaat gagcattgct tttggaatta tgttttttgt tactgtactt
    10621 cctgttgtgg tactcattgt atatttcaat cgcagctata ttttttctat tatactttct
    10681 tttgtatatg ctattttcaa ttttagtata tccttaaata ttatcaattt tgaaccaaat
    10741 aacccactat taagcgtatt acctgctcct gttataatgc gttggtggat ggcattttgg
    10801 ggagatccca ctggcgaata cacggcactt agacagccat atttgctctc aactcctgct
    10861 tgtgtaggta ttttatgttt gataaccatt atagcagtcc tgctgatttg tatgatatac
    10921 aaaaagcagg agaattagga ggtatctatg cttgatataa ttactacaga atttcaaaaa
    10981 ataaaaagat ataatattct atggattggt gttgttgctg ttctgttttc agcactattg
    11041 gcagtttttc aggttgtaag ttcacacggc agtgaccctc taacgtatga gagctttgca
    11101 aacggagtta tctggaataa tttcagtctt agttttccat ttgggattac acttattgga
    11161 ggatatctta ttaaccgtga atatacagac caaaccttaa aaaacatcct aactgttcct
    11221 atttcattac gcaaattgct agtgggaaaa ttaattgcgg ttggaggaat tgctgtattg
    11281 ttaagtcttt tcagcttctt atgcacattt attttggggt tgttattttg caatatcaat
    11341 atatctgtta cactcattgt aaaatcctta gttcagattt tgtctgttaa tctgtattgt
    11401 tatgttgctg ttttgccgat tattgcttat tttggtcgta aacaaaatgc atttctgacg
    11461 ggtgtaggga ttgcatttgt atacgggttt tgtggtgtgt ttgttgctgg aagaaatctg
    11521 acagactttt atccaatcac agcaggtctt ggtctagttg gatacaacaa tggtgctggt
    11581 actgtttatc agccacttat cggtgctatg actttgattg taattctaat cttgacaact
    11641 attctacttg tatttacacc taattatgat aaagttatga ccatatctaa gaaaaaaggg
    11701 ataaagcata aaaagtattc tcataaataa cataaatatt gtttctatta tttaagttgc
    11761 tagacagtga aaagaaaaaa tctgtcgtac agtggctata tgctcatgta ttcaagaagc
    11821 tacagttttg atttttcata actgtagctt ctttttgtat ttattaaatc acggctatca
    11881 taatacttgc aataggtata gcgacaagag agagtactgt catgtgtgtt ttatatatta
    11941 cattaagtat attctaaaat atatgtttta aataatatat ttgaaaatag gaatatttaa
    12001 ataaaaaaaa taatattata tatagttgac aaaaattggc aaatgatata atatataaat
    12061 atagaaatag taatcattac tattattaaa aagggaggaa ttaattatga acttaaaagg
    12121 aactaaaaca gaaaagaatt taatggcagg atttgcagga gagtcagaag caagaaataa
    12181 atatacatac tacgcttcaa aagcaagaaa agaaggttat aatcaaatag ctgctatatt
    12241 tgaagaaact gctaacaatg aaaaggaaca tgctaaatta tggtttaaac ttttacatga
    12301 tggtatgcct tcaacagagg aaaatttaaa ggatgcagca gcaggtgaaa actatgaatg
    12361 gactgatatg tatgcaaaat ttgctaaaga agctagagaa gaaggatttg acaagatagc
    12421 ttatttattt gaagctgttg gaaaaataga gaaagagcat gaagaaagat acttaaagct
    12481 tttagaaaac ttaaatgaag gaaaaatatt taaaagagat gaagaagttg tttggcaatg
    12541 tcaaaactgt ggtcatgtgt atgtaggtac tgaagcacca gaaaaatgcc cagtatgtga
    12601 ccatccaaaa gcgtatttca atataaaagc tgaaaattat taaaaattat cattattaaa
    12661 aaggaatgtt aactatgaaa ttttctaaac aacgagaact gattttaaat gaaatattaa
    12721 ataatccggt tcatcctact gcggattacc tatatgaaaa cttaaaaaaa gataatccaa
    12781 atttaagctt aggaactgtt tatagaaatt tagctcagct aacggaacat ggctttataa
    12841 gaaaggttag tattccaggg tatccagata gatttgatgg tcgaatagat aatcactatc
    12901 atatcatatg tgaagtatgt ggagaggtat acgatttaga atccgaagtt cttaataatt
    12961 tacaagaatt aatatctgag gagacagaca taaaaataac atcttataac ataagtttta
    13021 aagggatttg taataattgt aaaaggtgta gccaagtagg ttagttttca aattctaaaa
    13081 ataattaatg aggtgagttt atgtgtagtg aacaaaaatt ttttatatgt gagacttgtg
    13141 gaaaccttgt aggaatgata caaagtggtg gtgtacctat tttctgttgt ggaaaaccta
    13201 tgaaggaact tgttcctaat acaacagatg cagcagttga aaaacatgta cctgtaattg
    13261 aagtggatgg aaataatgtt actgttaaag taagtagcac aactcatcca atgactaaag
    13321 aacatcatat agcatgggtg tatcttatga ctgaacaagg tagtcaacgc aaatgtctag
    13381 cagtagatgg agaacctgta gttaaatttg ctttgaatga tgatgataaa gtgatttctg
    13441 cctatgctta ctgtaattta catggattat ggaaggctga actgtaatat ttaaataaat
    13501 tgagtcaaag aggaggctat aaatgtattt tcatacaaat agcctcctat aaatttatat
    13561 aaattcaagt tttaattttg tttaatgtca atataatata aggagaaaat aatatgtcaa
    13621 tttataaatg tagtgtttgt ggatatattt atgatgaatc taagaatgat aaaacatggg
    13681 atgaattaag tgaagattgg gaatgccctg tatgtacaaa aggtcgtagt tattttggaa
    13741 agataagcac tgtttactat gaagaagatg aaaagatagc agaagacata gttgaaaatg
    13801 aatctaaatt aaatactgaa aaagagggag atttaaatta cttaagtaca tatttaagaa
    13861 gagatgatga agttgagaaa catatggata taattcacga aatggctgtt acaggaaaat
    13921 ctataataga acctatgaga actaaactac cagtaatttc ttgggatgat attttaatta
    13981 tgggtgctca attaaatcca ttacctttaa atgagcatga tgaagtaaat acaacaacaa
    14041 taataggaaa aaaagcaaag aaacctatga ttatagaaaa tccagtttat atttcccaca
    14101 tgtcatttgg agctttgtct aaagaactaa aaatagcttt agcaaagggt gcagcccaaa
    14161 ataagacagc tatgtgtagt ggtgaaggag gtatattacc agaagagaag gaagcttcat
    14221 acaagtatat ttttgagtat gtaccaaata aatatagtgt aactgaagaa aatcttaaaa
    14281 attctgatgc tatagagata aaaattggtc aaggaacaaa acctggtatg ggaggtcatc
    14341 ttcctggcga aaaagtaact gaagaaatag caaaagtaag aaataagcct gtaggtcaag
    14401 atgtaataag tccatcttgt tttgaggaaa tacaatccaa agaggattta aagaaactta
    14461 tagatgaact tagagaagtt tcagaagggc gtccaatagg tgttaaaatt tcagcaggtc
    14521 atattgaaaa agatatggaa tttatagctt atgctaaacc tgattttgta actattgatg
    14581 gtcgtggtgg agctactgga gcaagtccaa agttgcttaa agatgcaact tcaattccaa
    14641 caatatttgc tctttatcgt gctagaaaat acatagatac acatggatta gatatagatt
    14701 tggttataac aggtgggctt cgtatatcta ctgattttgc taaggcaatt gctatggggg
    14761 ctgatgcagt tgctattgca agttctgctc ttatggcagc ggcgtgtcaa caatatcgta
    14821 tatgtggttc tggtaagtgt cctgtaggag tagctactca ggatgaggaa ttgagaaaaa
    14881 gattacatat agaaaatagt gctaatagag tggcaaactt tttaaatgta agtttagaag
    14941 aacttaagac ttttgctaga atttctggtc ataaagatat acatgattta agtgttgatg
    15001 atttatatac tgttaactct gaaatatcaa attatacaaa catacagcat gtatagattg
    15061 aagtttgaaa ctattagatt ttagatagct ataaaagtaa atgataaata tattttataa
    15121 aagagagtgt cttaaaatga actttttagt tcataagtca ctcttttttg tatgaagcca
    15181 aatatattta tcattttagc aatgaaaaag aatcttatct ctttattttg agatagactc
    15241 cttctattta tgaaaattaa agatattaaa ttgtaaaata ttctgtgatg tcgtactatt
    15301 aaactaaaga ttctgtactt taaagtaaat aaaaatttaa ggagtgctta ttatggaaag
    15361 attgaagata caagttttag ttgacaataa tacttatatt gatagatact ttgttggaga
    15421 accagcagta agctattata ttgagattga tggaaatagg attttgtttg attcgggata
    15481 ttcagatgta ttcatatcaa acgctgaaaa attaaatata gatttaggaa atttaactca
    15541 tgttgttttt tctcatggac ataatgacca tacaagaggt atccagtttt tagaaaatag
    15601 gtatgattta tctacagttg aacttatttc acatcctaac tgttttatac ctagaaaaca
    15661 tggagagaaa agcataggag ctccattttc tgctgaggaa attaaaaata tttttatgta
    15721 taatcctaag gataagccat ttaatctaag taagaattgt gtgtttttag gtgaaatacc
    15781 ttctataaat aattttgaaa aaagagctaa aattggtaaa tgtaaaatag gagatttgtg
    15841 ggaagatgat tatgttttag atgattctgc tatagtttgt aaaactgata aaggtatttt
    15901 tattgttaca ggatgttctc atagtggaat ttgtaatata gtagagtatg ctaaaagggt
    15961 atgtggagat gatagagtta ttggtatact aggtggtttt catctttttg aattgaataa
    16021 taggttagat agtacaatac aatatttgga taaagaagaa ataagaatgt tgtacccttg
    16081 tcactgtgtt tcttttaagg taaaagctaa gatgaatgaa atattgaata taaatgaagt
    16141 tggagtaggg ctgaccataa gtatatagta tttgaaagta tataagattt aagttgaagg
    16201 ttaaaaagat attttctata taaagtatct tttttgttac gtttatttta agagaaatca
    16261 atatactttt atatgaaata ttgtaaaaaa atttattttt aatgagaata tattttcatt
    16321 aataaac
//
LOCUS       DAMJWO010000221        10186 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.guided.110, whole genome shotgun sequence.
ACCESSION   DAMJWO010000221 DAMJWO010000000
VERSION     DAMJWO010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10186
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.guided.110"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            247..864
                     /locus_tag="PC366_003881"
     CDS             247..864
                     /locus_tag="PC366_003881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDF2579318.1"
                     /translation="MCKKTYLLVVSILIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIITPQQAMEIALKEQNG
                     MVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            972..3503
                     /locus_tag="PC366_003882"
     CDS             972..3503
                     /locus_tag="PC366_003882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDF2579319.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVKEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            3937..4638
                     /gene="vanR"
                     /locus_tag="PC366_003883"
     CDS             3937..4638
                     /gene="vanR"
                     /locus_tag="PC366_003883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanR-ABDEGLN family response regulator
                     transcription factor"
                     /protein_id="HDF2579320.1"
                     /translation="MNENILIVDDKKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KDLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            4688..5770
                     /locus_tag="PC366_003884"
     CDS             4688..5770
                     /locus_tag="PC366_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDF2579321.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            6027..7127
                     /gene="vanG"
                     /locus_tag="PC366_003885"
     CDS             6027..7127
                     /gene="vanG"
                     /locus_tag="PC366_003885"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HDF2579322.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            7124..7930
                     /locus_tag="PC366_003886"
     CDS             7124..7930
                     /locus_tag="PC366_003886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDF2579323.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            7948..10086
                     /gene="vanT"
                     /locus_tag="PC366_003887"
     CDS             7948..10086
                     /gene="vanT"
                     /locus_tag="PC366_003887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HDF2579324.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
BASE COUNT         3868 a         1067 c         1836 g         3415 t
ORIGIN      
        1 tcaaaatgaa ctttttagtt catgaggcac tctttttgta cgaaataaaa tatattttta
       61 ttatttcaac aatgaaaaag atgcttgttt ctattttgag acagtataat ttttatgtaa
      121 ctttaatttt agtaaatata aagttttaaa attgataaaa taggaggaat ttttaatata
      181 aaagggtaaa taaagggttt agagggcata atatagaata aattaatata tttaaggagg
      241 atttttatgt gtaaaaaaac gtatttatta gtggtaagta tacttatagc aggtttatta
      301 actgcatgta gtgggagccc aactaaggat tcaggacaag cacaagataa tacaaaaaag
      361 gaggcaaatg cttcaaataa tgctttaaaa gatgaaaaaa ataatgaaaa tttaatggaa
      421 caagatttta aagtgccata cacagatgca ataaacatat ttaaagataa atacaaggat
      481 gctgatatag tagatttaag tcttgagaga gatttaaata aatttgttta tactgtggaa
      541 ggtgtagatg ataataatga atataagatg aaaattgatg ctaatacaaa agatgtatta
      601 gaagataaaa cagaaaagtt agattcagaa gatttaaatg gagttgctag aaaagaaaaa
      661 ttagatttaa atgacataat tacacctcaa caagctatgg aaattgcatt aaaagaacaa
      721 aatggaatgg ttaaagaatg gagtttagac aaagatttag atgttacttt ttataaaata
      781 agaatagata aagataaaaa tgaatatgac ataaaagtag attctaaaaa gggaactgta
      841 ttgaaggtag aaaaagaaga ttagaagatt taaactatct ttaaaataat ttcttttttg
      901 aataaatttt gtttaaaata taacaagcag ggtataaaga gactaaataa ctattttagg
      961 aggagtacgg tatgtcattg aaatcactaa aaataaaaga aaatttatat tgggtaggtt
     1021 cacttgaccc tgatttaaga gtatttgaca taattatgta tacaccttat ggaactactt
     1081 ataattcata tgtattaaaa ggaacagaaa aaacagtttt gtttgagaca gttaaagata
     1141 agcattttga caattatatt gaaagattaa atgatttaaa tatagatttt gaaaaaatag
     1201 actatattgt tgtaagtcat actgaaccag accatgcagg aagcgttgaa aagcttttgg
     1261 atttagctaa aaatgcaaaa gtagtagctt cagaaacagc aattaaatat cttaaggaaa
     1321 tcgtaaacaa agactttgaa tatgttgcag ttacagatgg agatacatta tcaattgggg
     1381 acaaaacttt agaatttttc tctgtaccta tgcttcattg gccagatact atatacacat
     1441 atataaaaga ggataaaact cttgtaacat gtgattcatt tggtagtcac tatagtaatg
     1501 ataagatagt aaatacactt gatgaaaatg aagaaaagga ttacttggat gctttaagat
     1561 actattatga ttgtataatg ggtccattta aaccatctat ggtaactgct atagaaaaga
     1621 taaaagattt agatatagat actgtatgtc caggtcatgg tccagtatta actgaaaatc
     1681 ctagaaaaat tatagacctt tattataact ggagtgtaaa ggaacaaata aagttagaaa
     1741 aagaagttac aatttgttat gtttctgcac atggatatac aaagattatg gcagaagcta
     1801 taaaagcata tattgaaaaa aatagcaact ataaagtaaa tttatttgat gtaatagagc
     1861 ataagcaaga agatattttg gcaaaaatag cagtatcaca aggtgtatta tttggaacac
     1921 caacaatatt aggagatgcg ttaaagccta tatgggatat attaatatcg ttaaacccag
     1981 ttcttcatgg tggaaaagtt gcttcagtat ttggttcata tggatggagt ggagaaggta
     2041 tagaaaatgc tatggagaga ataagtcagc ttagaatgac agcagtaaaa ccttttgctg
     2101 ttaactttaa accatcaaat gaagagattg ataaattaca ttcttataca ggtaaattcc
     2161 tagataagtt aaattctact tttggaagta aaaagaaaac taagaaattt aaatgtgtaa
     2221 tttgtaatga agtttttgaa ggtgatagtg ctcctagtgt atgccctgta tgtggagcta
     2281 aggaagacca atttatagaa gttgaagaag atgaagttac ttttagaaaa gatactgatg
     2341 aatatttcgt aatagtagga aatggagcag ctggttttta tgcagcagat gctataagaa
     2401 aaagaaataa aacttgtaag ataactatga tttctaatga agatgagttg acttactata
     2461 gacctgcact ttctgatggt ataaatgaag aacttggttc agatttctac atggaagata
     2521 aagattggta tgataaaaat aatatagtag taatattagg aacgaatgta gataaattag
     2581 atgaagtgaa taaaactatt atagtgaatg atggagctat taaatttgat aagcttgtaa
     2641 tagctacagg aagtagaaac tttataccac cgattaaggg ccatgattta gaaaatgtgt
     2701 ttactcttag aaatataaaa gatttatata gtgtaaaaga agcactagaa aaatctaaga
     2761 aagttgtagt gattggtggc ggtttattgg gacttgaagc tgcatgggaa tttagactaa
     2821 aaggattaga agtagtagta gttgaagcca tggatagcat actatcaaaa caacttgata
     2881 aagagggtag taaaatatta gaacaatgtg taagagatac aggaatagat gtaagattgg
     2941 gtgtagcagt tgatggtatt gaaggtgatg gaaaagctca aaaagttgta tttaaagatg
     3001 gagatagtgt tgactgtgat atggtagtat tttcaattgg tgtaagagca aacactcaaa
     3061 tggttcagga tacatctgta aaaattgata gaggtattgt tgtagataag acattacaga
     3121 caaatgttaa agatatatat gcttgtggag atgttgcaca agtgggaaat attagtttag
     3181 caatatggcc atcttcagta gaaatgggaa aaatagcagg agcaaatgca agtggagata
     3241 atttgacatt tgaaagtgaa gtatatccag tttcattaga tgcaatgaat gtaaaagtat
     3301 ttagtattgg taatatacaa aattttgata aagaaatttc atcaaaagat gaaggtcaaa
     3361 gaatatataa aaaattattt atgaaagatg gttcattagt tggagctata cttataaatg
     3421 atttaagctg tactgttaaa ttgataagat taatatctga aaaaggtgat tttgaggata
     3481 ttatgaaggc tgatatacta taatttaaat acattaaaat aaaaaggagt tgtctcaaaa
     3541 ttgatttttt tctaatcaaa ttttaaattc aactcctttt ttgaattttt atataaaata
     3601 acatggaaat tttagtaatg tctgtggtta catacatagg tttaattgtt ttttatatgg
     3661 attgtctctg gtataataaa ttgaattgtg tttgactgat agatattttt attgaaagtt
     3721 aatacctgtt atgcgataat aaggacgtgt taggggagtt tttataataa caattaatct
     3781 cagtttttgt gttccaatag tagcatcaac acattctgat gtagtagttc ttttcttata
     3841 aaaattagtt acaaatatgc ttgtaattat ttgatatgta aatttaccaa tattataaat
     3901 gatgacctcg ataataagga gagtgaaaaa taatctatga acgaaaatat tttgattgtg
     3961 gatgataaaa aagaaatagc agatttaatt gaagtatatt taaaaaatga aggttttaca
     4021 gtatacaagt tttatacagg taaggaagct ctagaatgta ttgaatctaa agatttggat
     4081 atggctattt tagatattat gcttcctgat attgatggat ttcatatttg ccagaaaatt
     4141 cgagaaaaat actattatcc tatcattatg ttaacagcta aaattgaaga tatagacaag
     4201 ataatgggtt taaccatagg tgctgatgat tatataacaa agccatttaa ccctttggaa
     4261 gttgttgcaa gagtaaagac acaattaaga agatatatgc gatataataa ttcttatgaa
     4321 caacagtcga taattgttaa tgagtatgat attaaaggat tgattatcaa taaagaaaca
     4381 cataaatgta gtttatttgg gaaagaagta gcattaacac cgattgaatt ttctattctt
     4441 tggtatttat gtgaacatca aggaaaagtg gttccttctg aagaattgtt tgaagctgta
     4501 tggggagaaa aatatcttga taataataac acagttatgg ctcatatagg gcgattacgt
     4561 gaaaaaattc atgaaccttc taaaaacccg aaatttataa aaactgtatg gggagtaggt
     4621 tatacaattg aaaagtaaaa atattaaagt caatcctgac tttactcaag tgagaaataa
     4681 aatttttatg agaacagctt taatggcatt tatagccatt attttcatat ggattttata
     4741 ttcttttata ttgtatggta agttttctat ctggatagta tcattctttg aaaatgcttt
     4801 tcgtatggaa tataaagctg cattgaattt atatcagcag attttccgta atagcatgga
     4861 gctcttcatg atactagcta tggtgattgt gttttttata atattccgtg tttatttaaa
     4921 ttggtttaca aaatatttta gtgaaataaa tcaaggtatt gactctctta tcaaagaaga
     4981 tgttggagaa gtggctttat ctccagagtt attggcaata gaaaagaaaa taaactcaat
     5041 taaacatata cttgaacaac gtaaatttga gacacaaatg gcagaacaac gtaagaatga
     5101 acttattgtt tatcttgcac atgatttaaa aacaccactt acatcagtta tagggtatct
     5161 gacactactt cgagatgaaa gtcagatttc tgaagaactg cgaaaaaaat atttatctat
     5221 ttcgttggat aaggcagagc gtcttgaaga tttaattaat gaattctttg aaattacaag
     5281 gtttaattta tcaaatatat cacttgaata cagtacagta agcttaactc gtatgcttga
     5341 acaactaaca tatgagttta aacctacttt gatgagtaag aatttaaaat atacactgaa
     5401 tgttacacca aatatgatga taaggtgtga tgttaataaa atgcaacgtg tatttgataa
     5461 cttattacga aatgctgttt attatagttt tgaagatact actattgaaa taacagctgt
     5521 acaggaggat gattatataa agcttaaatt tataaatcat agcaatacga ttccagagga
     5581 aaaacttgag cgtatttttg aacaatttta caggttggat acatctcgta attcaaacag
     5641 tggtagagct gggttgggac ttgctatagc taaagaaata gtggagcttc ataacgggac
     5701 aataacagct catagcgaga acaatataat tacctttaag gttattattc cgattgtagg
     5761 aaatttgtaa gaatttaagt ataaaaaaat aggaaattct ttaggataaa taaagagcac
     5821 tcttgttatt gatataatta ctgtatcaaa acaagagtgc ttttattttg atacagtaat
     5881 tatatcaata gaaaaatgtg aaaatatatt atgtggaaca gatgcaattg taagtgaagg
     5941 ttgattggat ttgaaataga aaaagtattt taacatgttt ctgtagattg tataaaaata
     6001 aataaatcaa caaaggagaa tcaaagatga ataataaaaa aattgcagtt atatttggtg
     6061 gaaactcaac agaatatgat gtatcattac aatcagcttt tgcagtactt gagaatttga
     6121 atacggaaaa atatgatatt ataccaattg gaattacaag ggagggtaat tggtatcatt
     6181 atattggaga ttataataat atccagaata acacttggtt tgaaagggat actgatataa
     6241 ttccagttat tgtttcgcag aaccgtgtca aaaatggtat tattgaattt ttaattcctg
     6301 atgctgtttc tcagaatcat attccaaata gtgctattga atcatgtgaa aatgatatta
     6361 aatacactaa acttgatttt gtatttcctg tattgcatgg aaaaaatgga gaagatggaa
     6421 cagtgcaggg gttatttgaa ttggcaggta tacaggttat tggatgtggt actctttctt
     6481 cagcattatg tatggacaaa gacaaatcac ataaacttgt tcattcagaa ggtattaaag
     6541 taccaaaatc aatattacta aaatactcag ataaatttaa tgtggctgaa ctgtcaaaag
     6601 acttaactta tccattattt ataaaacctg tgcgtgcagg ttcatcattt ggtattagta
     6661 aaatttataa aaaagaagag ttacaagtag cagtagactt ggcttttgaa catgataatg
     6721 aagtaataat tgaggaaaat attgatggtt ttgaggtagg gtgtgcagtt ttaggaaacg
     6781 atgacttact tgttggaaga gtagatgaaa tagaattgtc aaaaggattt tttgattata
     6841 cagaaaaata tacattgaaa agttcaaaaa ttcatatgcc agctagaatt gatttggatt
     6901 gtgagaaaag aatacaagag acagcaaaaa ttatttatag aactcttgga tgttctggat
     6961 ttgctagagt agatatgttt ttaactccat ctggtgaaat tatttttaat gaagtcaata
     7021 caattcctgg ctttacttct catagtcgtt atccgaatat gatgaaaggt attggactgt
     7081 cttttgaaga aatattggat aagataattg aggtgtacat aaaatgatga ataatatttt
     7141 attagataaa aataaagaag ataaaatgac aaatactatc ttattgacta aagataaagt
     7201 ttatgatggg aatctaattc tagtaaatgc ttttttacca gttaaaacat ctgaagatat
     7261 agatttaatt cctgtagata caaggtttcc aagtattctt atgaaacgtg aagctacaaa
     7321 tattttacaa aatattttaa aaagtatatg tggaataaat gaaatagtac ctgtaagtgg
     7381 atatcgtact gcagaggaac aacaagatat atattcaagc tctctgcgtg acaatggaaa
     7441 agactttact aaaaagtttg tagcacttcc aaatcacagt gaacatcaga cagggcttgc
     7501 tattgattta gggttgaaga aagaggttat agattttatc tgccctgaat ttccttataa
     7561 tggtatttgt aatgagttcc gtaaggcagc actacattat ggttttatag agcgttatca
     7621 gtgtaaaaaa gaagaaataa caggaatatc tcaagaacca tggcattttc gttatgtcgg
     7681 atatccacat tctgagatta tcaataaaat gaatctcgcc cttgaagaat atatagaata
     7741 tattaagaga ttttcgtata caaattgttt aaaaatagaa gataaagaaa aaattataga
     7801 aatcttttat gtgcctattc atactaaaga agaagtgaga atctctatac ctgaacaatg
     7861 tgtatatcaa atatcgggta acaataagga tggttttatt gtgacatttt ggagaaatag
     7921 aaaggactaa gaaatggagg aacaagaatg attaggaata aatcttatgc agggcttgat
     7981 tattttagga ttatagctgc attacttata attgcaattc atacatctcc attattatca
     8041 tatagtaaaa tggctgactt tgtgttaact agtataattg ctcgtattgc tgtgccattc
     8101 ttttttatgc tatcaggctt ttttctaatt tcaacatata attataattg taataaactg
     8161 aaatcttttc taaaaaatgt attatttatt tacgggatag ctattgtaat ttatattccc
     8221 ttaaatattt acactggata tttttccatg aataatttag tgcccaatat tattaaggac
     8281 attgtatttg atgggacttt atatcattta tggtatctac ctgcatcaat tattggtgca
     8341 agtattgcat actttcttgt aaaaaaacta ggtttaaagt actcattagt aatcactatt
     8401 gttatttatg taattggtat gtttggtgat agttattatg gttttttaga aaaaatacca
     8461 ctattaaaga atttatatgg gtatattttt gaagtatcag attatacacg aaatggtata
     8521 ttttttgcac ctgtattttt catacttggt ggaataatat ctaataaatc taattatatg
     8581 tcaactaaaa atagcttgat tggatttctt atatcattct tacttatgtt atgtgaggga
     8641 atgtttttac ataaactagg ggtacagcgt catgatagca tgtatattat gttattgcca
     8701 tgtatgtatt tcttatttac agccttaaca tttttaaaag gttctcgagc taggttattg
     8761 cgaacatcat cattaattat ttatattata catcctatga tgattgttgt tattcgtatg
     8821 ttttctaaaa tattcggaat acaaactgtc ttggttgaca atagccttat tcattatata
     8881 gtggtaagta tagcatcttt tatagcttct ataattatta tattgattct taaacctcta
     8941 aaaaaagact tgaaaggaga acataaggta aataccaata gagcttggat tgaaattgat
     9001 ttaaataatt tggaacataa tgtaaagatg atacaaaaag ctatgccaga agattgtgaa
     9061 ttgatggcag ttgtaaaagc taatgcctat ggtcatagtg cttttgaagt agcgacttgt
     9121 gcaaaccaaa taggtgtaaa agcatttgca gtagcaacaa tagatgaggg gattgattta
     9181 cgtcgatatg gaatactagg agaaatattg attcttggat atactaaccc aataagggca
     9241 aaggaacttc ataaatacaa tcttacacag agtgttattg accttaatca tgctatctct
     9301 ttaaacaaac agaaatacaa cataaaatca cacattaaaa ttgatacagg tatgcacaga
     9361 ctgggttttg atgttaatga tgtgaggtca attttaaagg catttaaatt aaaatactta
     9421 gatatatgtg gcatatttac acacttgtgt gtttcagata gtctgaaaga tgaagatgta
     9481 gactttacaa ataaacaaat tgaatgtttt tataagttaa ttgattttct gttaaaaaaa
     9541 ggtataaaaa ttcctaaagt acatattcaa agtagttatg gtttttttaa ttatcccaat
     9601 cttaagtgta attatgtaag aattggaatt gcattatacg ggatattaag ttctccaaat
     9661 gatacgacta aattgcaact tgatttacga cctgttttat ccttaaaatc acaagtaatt
     9721 cttattagaa aaatacaaaa agatgatagt tttggatatg gaagagtctt tattgcaagc
     9781 agagatagcg taattgctat attatctatt ggctatgccg atggtatacc tagaaattta
     9841 tcctgtggaa aaagttacgt aataataaat ggttgtagag cagcaatagt gggtcgaatt
     9901 tgcatggacc aacttgctgt tgatattaca gatataccta atgtagaagt tggtaatacg
     9961 gcaataataa taggaagaga taatttatct gaattatctg cttctgaagt tgcaaataac
    10021 tcatgtagta tatcgaatga attattgagc agagtaggaa gaaggttaaa tgttataaag
    10081 aagtaactca attaaatagt aatatttgtt gtactgtgta atttatttta ctctgactag
    10141 acatttttag taatattatg tctaatatat attttttata acttac
//
LOCUS       DAMJWO010000222         8195 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.guided.121, whole genome shotgun sequence.
ACCESSION   DAMJWO010000222 DAMJWO010000000
VERSION     DAMJWO010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8195
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.guided.121"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            82..798
                     /locus_tag="PC366_003888"
     CDS             82..798
                     /locus_tag="PC366_003888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579325.1"
                     /translation="MILIVILSIFIIASINIIILGKENIRDIVIPLTLFIVSDFLFLC
                     GNIICRGGVMLLFIGLFAIPLMLIAFIWICVHMIKLYYKKDLNKRKMIGCIFSIFISI
                     GTIFIPSPSESFRFKLYEKDYSVVAKAILKVYDEKKLSSESVFYIQSDKNELEKIFSK
                     EVIKKMKKLNRNLDVVKISGNRNLVYFFFGAELQSIDGIVIFKDLKHVKPKLDFINRS
                     IQAPRLEYITNNVYYFKGEL"
     gene            826..1764
                     /gene="blaCDD"
                     /locus_tag="PC366_003889"
     CDS             826..1764
                     /gene="blaCDD"
                     /locus_tag="PC366_003889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HDF2579326.1"
                     /translation="MKRKNNFIWIVILLVVVAMGVYYVGRKHNNTKQKHDKNHINSEL
                     NKSKVENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETRRSPCS
                     TFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYYKKLID
                     KVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQTMAKI
                     FEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGMLEREGD
                     TYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            2108..2791
                     /locus_tag="PC366_003890"
     CDS             2108..2791
                     /locus_tag="PC366_003890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDF2579327.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            2788..5448
                     /locus_tag="PC366_003891"
     CDS             2788..5448
                     /locus_tag="PC366_003891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDF2579328.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAQKSKGESFKKISETTLTIVGKVDVSTSSVIPAYTALGYLDRTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKMS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYINSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKTVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNTRSRRQEFAMLRSVGLSPE
                     GIKKMLVLEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(5629..6810)
                     /locus_tag="PC366_003892"
     CDS             complement(5629..6810)
                     /locus_tag="PC366_003892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDF2579329.1"
                     /translation="MKTPRNINSTVVFIIFCLIITFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(6810..7472)
                     /locus_tag="PC366_003893"
     CDS             complement(6810..7472)
                     /locus_tag="PC366_003893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDF2579330.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCGNISLNKVEVKAYLDNVEVLLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            complement(7617..8159)
                     /locus_tag="PC366_003894"
                     /pseudo
     CDS             complement(7617..8159)
                     /locus_tag="PC366_003894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
BASE COUNT         3044 a         1027 c         1298 g         2826 t
ORIGIN      
        1 ctattgtaat atttaaatat tacaatagta agttttaaat agagaataaa taattacctc
       61 acaaactgaa aggaggacat aatgatacta atagttatat tgagtatatt catcatagcc
      121 tcaatcaaca taattatatt aggtaaagaa aatataagag atatagttat ccctttaact
      181 ctatttattg taagtgattt tttatttttg tgtggaaata taatatgtag gggaggagta
      241 atgctactat ttataggttt atttgcaata ccattgatgc taattgcatt tatatggatt
      301 tgtgtacata tgattaagct ttactataaa aaagatttaa ataaaagaaa aatgattgga
      361 tgtatattta gtatctttat aagtataggt actatattta ttcctagtcc aagtgaaagt
      421 tttagattta aactttatga aaaagattat agtgtagtag ctaaagctat tttgaaagtt
      481 tatgatgaaa aaaagttaag ctctgaatct gtcttttata ttcaatctga taaaaatgaa
      541 ttggagaaga tattttctaa agaagtaata aaaaaaatga aaaaactaaa cagaaattta
      601 gatgtagtta aaatttctgg gaatagaaat ttagtctatt ttttctttgg agctgaatta
      661 caatctattg atggtattgt gatttttaaa gatttaaaac atgttaaacc aaagttagat
      721 tttataaata gaagtattca agctcctaga ttggagtata ttacaaataa tgtatattat
      781 tttaaaggtg aactataaac ttatgtagag gagatggtat aaagtatgaa aagaaaaaat
      841 aattttattt ggatagttat tcttctagtt gttgtagcta tgggagtata ttatgtagga
      901 agaaagcata acaacacaaa acaaaaacat gataagaatc atataaactc tgaattaaat
      961 aaatccaaag ttgaaaacaa tgataaaaac aaaaaagaaa aaattaatat ggttgactat
     1021 agtgactgtt ttgaaggtat tagtggagga gctatttttt ataatactaa aaataaagaa
     1081 tataatatat ataacaaaga attaattgaa acaagaaggt caccatgttc tacttttaaa
     1141 atagtttcaa ctttaattgg tttagaaaaa ggggtaataa actcaaaaga atcagttatg
     1201 ggatatgatg gtacagagta tccaaataaa aattggaata aaaatcttag tttagaagag
     1261 gcatttaagg agtcttgtgt ttggtactac aaaaaattga tagataaagt tgatgctaaa
     1321 tctgtccaaa acattttaga tgatttaaag tatgggaatt gcgatattag cgaatgggaa
     1381 ggagatttaa aaaatggaaa gggacattta aatggatttt ggttagaatc ttcattacaa
     1441 atatctccaa aagaacaagt gcaaacaatg gcaaaaatat ttgagggaga tacaaacttt
     1501 aaaaaagagc atattaatat tttaagagat attatgaaaa tagatgtaaa tgataaaaac
     1561 ataaatgtat atggaaaaac tggaacagga tttgatgaaa aaaataaacg tgtggatgca
     1621 tggtttgttg gtatgctaga gcgtgaaggt gacacctatt attttgctat taaatcagat
     1681 gattccaata aagaaattac agggccaaag gtaaaggaaa ttgcaattaa tataattaag
     1741 aaatattata gtgtaaggga ataaacttaa ttttatttgt aaatattatt tacctatagt
     1801 ctgtaatatt tattaaataa ttttactaaa ttgagtctat atagagcaaa actcctttag
     1861 tacataaaat acttgctatt gattattaaa ttgaatacct atagatttaa agttaatacc
     1921 ttttaaagac tatgtaatat attaaaagta taaataaaat atattgcata gtttttgttt
     1981 tatattataa ttttaaataa tgtgcaaaaa ctaaacaata tttttaatag taatttatat
     2041 ttgtattcat gtcactataa tgtcatttta ggttgctaaa atttaaccat aaaggagatg
     2101 attgtatatg gaaatattaa aatgtgaaaa tctcacaaaa atatatggtt caaatcaaac
     2161 cagagtgaca gcccttaata atgtaaattt atcagttcaa aaaggtgatt ttgtatccat
     2221 tgtaggagca tctggttctg gcaaatctac attgttacat ctgcttgggg gagtagatag
     2281 acctacatct ggaaagattt atgttgaaga tacagaaata tcaagtttaa aggaagaagc
     2341 tcttgcagtt tttagacgta gaaaagtagg tcttatttat caattttata atcttatacc
     2401 tacccttgat gttagaaaaa atatattatt acccatgtta cttgataaaa gaaaggtgga
     2461 tgaggataga ttctctgaga ttgtatctat attgggatta tctgatagat taaaccatct
     2521 tccaagtcaa ctttcaggtg gacaacaaca aagggtatct atagctagaa gtttaatcta
     2581 tagaccagct attttattag cagatgagcc aactggtaat cttgatagaa aaaattcaga
     2641 agaaattgta gacttgttaa acttatcaaa taaacgattt aatcagacaa tacttcttat
     2701 tactcatgat gagaaaatag cactagaggc aaatcgtatt gtaactatgg aagatggagt
     2761 gattgtctct gaaaaggtgg tgaagaaatg aatattcttc aagaatacac cttagacttt
     2821 gtacgacgca ataaacgtag tagtatagct ataatgttag ctatattact tactacaacc
     2881 atgatgtctt ctttgtgtgg actgttgtat accatgtgga cagattttat aagactttca
     2941 attgagaaag aaggtaactg gcatggtgaa ttgtttgact atacttatgg aagtgactta
     3001 ccattaattg aaaatttttc ttcagttgat gatgtaatgg taaaaggaca atggtatgta
     3061 ggcaaaatta atgatgagaa aagagattat ataatttata gaaatgctac atcagagtat
     3121 tggaattcta tgccagaaaa ggatactata atagagggtc gtcgaccaaa taatgctaat
     3181 gaaattgcat tatcaaaaca atattttgag aataatccaa gtgtaaaaat tggggataaa
     3241 attactcttc caataggaga tagaatccta aatggaaagc ctcttgaacc catagctcaa
     3301 aaatcgaaag gggaaagttt taaaaaaatt tcagagacta cattgacaat agtaggaaag
     3361 gtagatgttt ccacttcatc agtaatacct gcatatacag ctcttggata tcttgataga
     3421 acaagtataa aacctaatga tagtataact gtgtacttgc gatttaaaaa tataagagac
     3481 acatacaagg aacttccaaa acttgctaaa tcattggggt ggaagactaa tgaatatgga
     3541 aaatacaatc ttaaatataa tagtaattat cttttaaaaa tgttagtctt ttccccagaa
     3601 cagaaagcat ctatgagcag tatatcaaaa ttttcaactc ctattatgta tcttacaata
     3661 gcaattttta cagtagctgt gtttgtaatg gtgatttaca acgcgttttc actatctgca
     3721 aatgctagac ttactcaatt agggatatta tctagtgttg gtgcatcacc aaaacagatt
     3781 aaaatgtctg tagtgtttga aggttttttg cttacaatta taccattgcc aataggttta
     3841 tttttaggat ggttattgtg taataggctt atagtttata ttaattcagt taattatcat
     3901 actgatgttc cagaagtggt atttacttat ggtattcctg cttttctgcc agcagtttta
     3961 cttacaatag taacagtctg gatttctgca cttataccag cacgaaaagt atcaaagata
     4021 tctcctatag aagcaatacg acaaggagat agtgttaaaa tcaaaaagtc gcataaatat
     4081 tcattaggaa agatatttgg aatagaagga gaacttgcat caaacgcact acgtgctcgt
     4141 aaaaaatctt atcgtactgc aacaatatct ttaacattat cttttttatt acttacatgt
     4201 tttttgcata taattgcaaa tcaagaagga gcaaaagctg tttatggaag tgataattat
     4261 aaggaccaaa gagatatagc agtttatttg gaaaatagtg aacctgtaga gtctgctttc
     4321 attgaaaaat tagataatac agaaggtgta aaaagttcac tatattatca aaaaatgtct
     4381 gcttccactt ggctgactga aaaagatgca tcaaaagaac ttgcgaaaaa tggaggattt
     4441 aaaagtatag tttcatctaa aaaatactct cctatagaac gtgatggcaa gtttcgtata
     4501 atttcaaata taattgggct tgatgataag agttttacag aatattgtag gcaaatttct
     4561 gtagacccaa agttatttta tgatacaaaa aatccaacct caattgtata taataaggag
     4621 gaagatatta atcgtagtac acgtagaaat aaagtatata tagattattt aaatctttca
     4681 ataggagata acattaaatt aaatgaaaaa gtatatgacg aagataaagg ggattatact
     4741 tacaacatga aagtgggagc tattacaagc acacttccta aaacagtaga tactagttca
     4801 aaatatacat taatgcaaat agtgccaatg tctatggtgc aggaaatatc taaaaattat
     4861 gatgaagtaa gtaggttacg ttcaaatagg ctgataggag tatttaaagt aaataatcgt
     4921 gaggacattc ctagagtaag agaaaaatta gagtccattt ataataaaga ctatggttca
     4981 ggagattata gtattgagga tgttttagaa agtgaaaaac aaaaggctag tggaataaag
     5041 accatgaatt taatagtagg ctttattaca ggtttattgg ctatgattgg attatcaaat
     5101 gtacttgcta cagtgtcagg aaatactaga agtagacgac aagagtttgc tatgttgcgt
     5161 tctgttggat tatctccaga aggcataaaa aagatgcttg ttttggaagg tttgttctta
     5221 ggaattacac cattactact tagtattcct gtgcaaatag gaatagtgta tgcttttcta
     5281 cgtataaatg aaatatattt tatagagtat ttaccatttg cacctatatc tacaataata
     5341 ggttttacta tattgatact ttttattgta atagcatcat atatgacagg atacaagcag
     5401 ttgaagaatg aaaatatagt agaatctata aaaaatgaaa caatataaac aaaagctatt
     5461 tgaacttatt taaaggtttc gatttaagac tacttacaag tatagggata gttaatttgt
     5521 ttgtttaata aaaccttaaa tgtaaataga agtatattac taaaacaata gataacatag
     5581 aatatagata tagctggatt ataggtattt tacctataat ccagcatttt atgtgtaaaa
     5641 tttaattatg aatcttgcac caccattatg gcaattttct gcatgtagag taccattttg
     5701 acgttctata atagactttg atagagcaag ccctatacca atactgtcct tactagcatt
     5761 tttaccacga taaaatctat taaaaatata tggaagttct tcctgagcaa accctttacc
     5821 attatcttct atgataatct caacatatag aggattttga ctataataag caactatata
     5881 tccaccatct tctatatgct cactacaatt tttaagaata tttaaaagag cttctaaagt
     5941 ccaattaata tcgatttcaa attctaccga aggagaagcc tcgatagtaa atgtctgatg
     6001 tttttctctt aaagaacctt ctataggctc aattgcataa gtaagaagag aatgtacatc
     6061 tataagtttg ctttcaaata ttaaagtact tgcatccaat tttgataatg taagtaaaga
     6121 tgaaactagt ctctcaagtc ttgagatttg atttgtaagt ctgttaatat aatctatttc
     6181 ttcatctgga caattttctg aaagtaattg tgccataagt gacatagaag taattggagt
     6241 cttaagttga tgagcaatat ctgcaagatt atctgaaaga gtttgtcttt cttttaaagc
     6301 aaattctttt gaacaacgaa gttccccaac tgttttatat atctcatctt caaggtgaga
     6361 aaattcatct tcacatcgta aaagtacaga ctcttttcct aaattcactt cttctaagta
     6421 ttgagtaaga ttgtttattc tactcagttt ttgcttattt gttctatgtt tgattatata
     6481 tacaactgta gccattgttg aaattatacc aaacgatatc actagaaaat aaaaaaagtt
     6541 tttactccaa aatgtacttt tagaatatcc atgttttgat aaaatttcat ttcctgtttt
     6601 aaaatcctta tcactagaat ttttcagtga ttttagtata ctttctgtag acttaggatt
     6661 gtactcatat gatgcaccaa gagccttaga cagtacattg tattcattaa aagaagttat
     6721 agttgttaga attacactta ataaaaaagt tataattaag cagaatatta taaaaacaac
     6781 tgtactgttg atatttcttg gagttttcac tagctgtcct ccattctata tcctatgcct
     6841 cttaatgttt ttatacaagg tggatttttt aatttttctc taagacgctt tattgtaaca
     6901 gtaagagtgt tatcatttac gaaattacca tctacatccc agagcatttc tagtaacttt
     6961 gtacgggtca tagctctatt tttattttcc ataagactta gaagaagttt atattctcct
     7021 gctgtcaaaa gtacttcaac attatctaaa tatgctttga cttcaacttt attcaagctt
     7081 atatttccac atgtaatagt attgttagta tttgaatgag ttcttctaag aactgcatta
     7141 attctggatt gaagtactga gagcagaaat ggtttaacca catagtcatc tgcacccata
     7201 tctaatccac gtataatgtc tttttcatca tcacggactg tcaaaaatat cactggagta
     7261 tcttctatac ttttaacata ttggcaaaac tcgtatccaa taccatcagg tagatttaaa
     7321 tcaagcagaa ttaaatcaat agttttatca aaattttttt tagcttcagc aatcgtatta
     7381 taacaacata cagtgtgatt tttcttttca agggaagttt ttattccaaa tgtaattgta
     7441 tcatcatctt ctaaaagaag tattttagcc atttactttt agtcctttca gtaatttagt
     7501 tatttcatta actaagttat tagttttatg tttaatattt tttatgttag agatagaagt
     7561 tagagataga aaaaattatc atttaagtat ataaacttta atttataaac ttaggtttat
     7621 gctttaattg aatctattaa aagagcaaga gttgtttcaa taaatttttc ctcatctata
     7681 ttaaagttgt tcaggtatga ctttcctgtt acagatagta aattaaaaaa tcctgtaagt
     7741 gtaaatattg atgaatacat gagagtaggt atttcaatat catgcctaat acttctatca
     7801 ttttttccaa tttcaaacat tccttgtatt tcatcaaaca taaatttatt aaaagaaaaa
     7861 aacttttctt taaacagcat atcagtatcc gatttttcag agtttacaat accaatcatt
     7921 cccataaggc ataatagaga aggttctaca gagtaaaatt tatgaaaagc aaagtatgaa
     7981 agttttattt tttcaaaccc tgttttgcct tttgcacttt ctattttaac attatcccaa
     8041 agtcttttat atcctcttaa gacaacagca aagaataaat cttctttaca tgaaaagtac
     8101 ttgtatatgg tgcgtttagt atattcaact tcttttgcca actcattcat agttgtattc
     8161 tgaacctccc atgactaaag tcacagggtt cctgc
//
LOCUS       DAMJWO010000223         4720 bp    DNA     linear   BCT 12-JAN-2023
DEFINITION  TPA_asm: Clostridioides difficile strain NR-49286 isolate JH318
            SAMN32366160-rid16589883.guided.162, whole genome shotgun sequence.
ACCESSION   DAMJWO010000223 DAMJWO010000000
VERSION     DAMJWO010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN32366160
            Sequence Read Archive: SRR22862998
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001560854.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001560854.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/05/2023 00:58:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,899
            CDSs (total)                      :: 3,816
            Genes (coding)                    :: 3,771
            CDSs (with protein)               :: 3,771
            Genes (RNA)                       :: 83
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 45
            CDSs (without protein)            :: 45
            Pseudo Genes (ambiguous residues) :: 0 of 45
            Pseudo Genes (frameshifted)       :: 25 of 45
            Pseudo Genes (incomplete)         :: 18 of 45
            Pseudo Genes (internal stop)      :: 11 of 45
            Pseudo Genes (multiple problems)  :: 8 of 45
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4720
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN32366160-rid16589883.guided.162"
                     /strain="NR-49286"
                     /isolate="JH318"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="USA"
                     /collection_date="2011"
     gene            584..922
                     /locus_tag="PC366_003895"
     CDS             584..922
                     /locus_tag="PC366_003895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2579331.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
     gene            944..1261
                     /locus_tag="PC366_003896"
     CDS             944..1261
                     /locus_tag="PC366_003896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDF2579332.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            1411..2088
                     /locus_tag="PC366_003897"
     CDS             1411..2088
                     /locus_tag="PC366_003897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDF2579333.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(2416..3183)
                     /locus_tag="PC366_003898"
     CDS             complement(2416..3183)
                     /locus_tag="PC366_003898"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDF2579334.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKVAVMPQNERDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            3989..4621
                     /locus_tag="PC366_003899"
     CDS             3989..4621
                     /locus_tag="PC366_003899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HDF2579335.1"
                     /translation="MTIPNSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVSPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
BASE COUNT         1900 a          570 c          549 g         1701 t
ORIGIN      
        1 gattattact ctactataaa tcttgtatat aacttgtatt tataagtatt tgtatattta
       61 ttttttataa tctaaactaa tattatatat tttcattatt tttttaatta taattttttt
      121 aaaattttat tctaaatgcc ttacttataa ttaatttttt atttcaccta tatataatta
      181 gatttaaaaa tgtttacctt accaatataa tgattaaact caaaagtctt attgaaaaat
      241 tttctattta cataaattgt tcaatatata aaatagaaaa tttttttaat tttcaaaata
      301 tattctacat atctaatatg taattacaat aaaaaatgct ataattaaca tattattaat
      361 tcgttttatt attgtagtat ggctatgaaa ttatgaaaat atttctctaa ttaaaaatat
      421 gatttatcca tatttgttta ttgtagatac agactataca aaaataaata gcacttattt
      481 cagtataaaa acatatatag tctatattta gactaaaaaa gtataaatag tctatataaa
      541 acaacttaaa ctatgaatat aatctaaagt ggagggataa taattggcaa atataggaaa
      601 aataatagga gatagaataa aagtctatag aacaaaattg ggatatagtc aagagtttct
      661 agcagaaaag gcaggtttac atccaacata tattggtcag attgaaagag ctgagacaaa
      721 tacatctatc aatattataa tgaaaattgc tactgcttta gacataccac ttgaattgtt
      781 atttgcaaat attattacaa cagaaggcgt tgataactct gtacctttag aatgttatga
      841 aatgattaat aaattaactg aaaaagaaca aattgcaatg ctagagttaa taaagtgcat
      901 cattaaatac aaagaaatat aagtgaggga aatagtaaca ataatgaatt atataggtaa
      961 aagacttaaa gaagaacgaa aaaaagcaaa tttaacttca aaagaatttg caaatatggt
     1021 tggagtatcg ccttggtata taactcaaat cgaaagtggt aaaaagaatc caagtcttaa
     1081 aacattcata aaatttgtaa atatattaaa tatttctgca gatgttctta taaaagatat
     1141 tacttccact ggaaaaacat atttagaaaa tgatataaat gaagagttaa aagacttaaa
     1201 ttcaagagaa ctaaatctga tatcacagat tatagacatc ataaaaaaga ataaaatata
     1261 attctttata ttttatataa aaaaaaaggt tatttgaaat aaataacctt tttttgtctt
     1321 tttgtgttaa cattgtctta tagtgctaat gagtactatt agaccatgtt ctatggcctt
     1381 attttaatat aaaacgattg gagataggct atgattgtga ttgaaggtag tgataaattt
     1441 aagattgcaa aagaatatat tgatgtagaa tatactcttt ttagcaaagt aacttttagg
     1501 tatgaaaagt tgaaatttaa agataatgct gaattggaaa aaattaagat gtttaaatat
     1561 aaaaatggct acatccctaa taaattaaac ctttcttttg gatatggatt ctcttcttat
     1621 aaaaagcaaa taattagaga aactgtagat actttaagat tgacagaaat tttttcaagc
     1681 gagaacatag aagatattaa atttataaaa gatggtacaa aaaaattaga aattagcata
     1741 gagaaagttg tgaaatttaa acgtcgaaaa aaaagaaatt atgtttgttg ctattgccct
     1801 gatatgtata gagatataaa actcgacaaa gaatctatca ataagatata caacagaaaa
     1861 ataaaaatag aaagagaagt taatattttt gaagatgagg atgttataat aaacaagaaa
     1921 gtattgaagt ttccaaagtc ttggacaaag aatatgcaaa aatattggtt aagtgaaaat
     1981 aagtatccca tacattctac tgtaattgat gatgatagat ataaatgttg taatgtacaa
     2041 tatacaaaaa atagagtgat aatattatat tacatatata accattaata tacataatta
     2101 caaaaaaata atgacaaata tacataatac aaatatatct tctactttag ataaaacagt
     2161 tattatgaaa acttactatc tataaataat agaaatgcta gtataccatc tataatctaa
     2221 tgtctagtag gttttaatgg catattttaa atatgccata gttgatttat aagattttct
     2281 atatcacttt caaaatacac actaaatagt tgcttttcag atataattgc ccaatttaaa
     2341 ttttactatc tgaaaagttt tttatattta atttatatct tcaaaaatac cgtctaatat
     2401 ttctatataa ttaatttaat taatactctt atgtaataga ttaagtactg aatttaactc
     2461 tttaaatgat atttgccctg gtgctgaaac actttttgca gctccaaaag tcaatgcaga
     2521 accaaatatt tcaccacaca atctacttat aacacccatt cctgacattg acattgttat
     2581 tattggtcta tctgcataaa ttttaaacat ttcatttgta gcttcaagta gcactaacac
     2641 atctctttca ttttgcggca taacagctac tttgggtaaa tctgcgccca attcctgcat
     2701 tctacataaa cgagatacaa tctcttcttt ttttggagtt ttattaaaat catgattaga
     2761 tataattact ttcacttctt ttttatgagc aaaattaact acttcatcta tgacctcatc
     2821 tcccataaat aactctacat ctattaaatc tactaaacct gtattagaaa tttctttatt
     2881 caaagtagta taataatctc ttgatattaa tttttctccc ccttctacta cacttctaaa
     2941 tgtgaataat aaagggatat catgtatata acttcttaat tcatagagaa cttccttaac
     3001 ttctttaata ttttctacat tctcaaaaaa atcaactcgc cactctataa tatccaaaca
     3061 tgcatctttt aactctttag cctcttttat aatatctttt ttatttttcc caataattgg
     3121 tacacaaatt ttaggtctac cttctccaat agtaatattt tttacttgaa cttttctttt
     3181 catattctcc tccataatca gaaattctat aggactttaa attctatttt ctgcataatt
     3241 taattataca ttaaaaatac tatacattat aaaaatacta atttaaaaat aatttttatt
     3301 ctaattctta aaacaatccc acatatttta gaaaaggtac tctataatat acaaacactt
     3361 cttttttacc taaatttatt ttaacattct ataattttca caatattctt taaattttac
     3421 tcatataaac aatattattc tggatgctaa tagaattaat ctataaatca tagtataatt
     3481 atgcagaaat aactcgaatt tcactactta taaagagatt gaatattaat gaatctaaat
     3541 catttgcatt acttcagagt tttgactaaa gttgaacacc atacaaaagt agctactcaa
     3601 ttgtttatac cccaaccaag cttaagtaat gttatataga ttcttgaaaa agaatttggt
     3661 atctttttat ttgaaaaaca aggtagaaat gtttccctca ctaaatacgg aagttttttt
     3721 ctaacctatg ttgataaagc attaggttaa ttagaaaaag tttacatata aaatatatta
     3781 aattgttgca agttttattg ttttgatata caatcaacta aacatataat ctttataaaa
     3841 tactatacag ttaaaagtct gttttaaaaa aaaatgtata aattataaat caaaatatag
     3901 atactatcaa ggagtgattc tgtgaagaga tgtattgtag tagtggaata gtcaaaaaca
     3961 taatatatat taaaggagag atttaaatat gactattcca aattcaaata aggtatatcc
     4021 aagaagtaat gattatcaaa ctgtatatct taaaaatgta ataacaaggg aaaatataga
     4081 agttggagat tacacaatat ataatgactt ttataatgac ccaagagatt ttgagaaaaa
     4141 caatgtatta tatcattacc ctataaacaa tgataaatta ataattggta agttttgctc
     4201 aatagcatgt aatgcaaaat ttctaatgac tagtggaaat cactcaatga aatcaaaatc
     4261 cacatatact tttcccatct tttatgaaga atggaaactc gatatcaacc atataacgga
     4321 cgcttgggac aataagggta acattataat tggaaatgat gtgtggatag gttatgattc
     4381 tataattatg tcaggtgtaa atattggtga tggtgcaatt attggaacaa gagcagtagt
     4441 tactaatgac gtctcaccgt attctattgt tggaggagta cctgcaaaaa ttataaaaaa
     4501 gagatttaat aatgatacaa tttcaaaatt attagaaatt aaatggtggg attggccata
     4561 taaaaaaatt caatcaaaca ttaagcatat tcaatcagga aatattgata aattagttta
     4621 atattttata atttatttat attaaacttt actttaataa tccttttata agagcttttt
     4681 caaaatttgt atattatttt aatatatata aatttaatac
//
